LOCUS       DAPHKZ010000001        88170 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.001, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000001 DAPHKZ010000000
VERSION     DAPHKZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 88170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88170
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.001"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            183..632
                     /gene="alaE"
                     /locus_tag="RH288_000001"
     CDS             183..632
                     /gene="alaE"
                     /locus_tag="RH288_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HDV4029114.1"
                     /translation="MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYS
                     RLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIKNLADILAYVTFQSPVYVAILLV
                     VGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA"
     gene            complement(669..1013)
                     /locus_tag="RH288_000002"
     CDS             complement(669..1013)
                     /locus_tag="RH288_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HDV4029115.1"
                     /translation="MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARM
                     GRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVAL
                     ERYLNGLFGEAS"
     gene            1165..1494
                     /locus_tag="RH288_000003"
     CDS             1165..1494
                     /locus_tag="RH288_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HDV4029116.1"
                     /translation="MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAE
                     AARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGA
                     LLSMRKS"
     gene            1742..1987
                     /gene="nrdH"
                     /locus_tag="RH288_000004"
     CDS             1742..1987
                     /gene="nrdH"
                     /locus_tag="RH288_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDV4029117.1"
                     /translation="MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALR
                     AQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA"
     gene            1984..2394
                     /gene="nrdI"
                     /locus_tag="RH288_000005"
     CDS             1984..2394
                     /gene="nrdI"
                     /locus_tag="RH288_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDV4029118.1"
                     /translation="MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYIL
                     IVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCG
                     VPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA"
     gene            2367..4511
                     /gene="nrdE"
                     /locus_tag="RH288_000006"
     CDS             2367..4511
                     /gene="nrdE"
                     /locus_tag="RH288_000006"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDV4029119.1"
                     /translation="MATTTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAF
                     IATHVRPNSVTFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHTSGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLALQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADVAISQHYDEL
                     VADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASEYDENLDYTRTGHDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSH
                     IRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYAITWHALRT
                     SMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELFTRSGITLPTREMW
                     AQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPA
                     PFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL"
     gene            4521..5480
                     /gene="nrdF"
                     /locus_tag="RH288_000007"
     CDS             4521..5480
                     /gene="nrdF"
                     /locus_tag="RH288_000007"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDV4029120.1"
                     /translation="MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLTVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMPDALTPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKISLGQREEL
                     KSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMA
                     EVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF"
     gene            5834..7036
                     /gene="proV"
                     /locus_tag="RH288_000008"
     CDS             5834..7036
                     /gene="proV"
                     /locus_tag="RH288_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
                     /protein_id="HDV4029121.1"
                     /translation="MAIKLEIKNLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGV
                     KDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRE
                     VRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHS
                     YPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTI
                     VFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSA
                     KDIARRTPNGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKTALT
                     QQQGLDAALIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRAL
                     DREGVNNG"
     gene            7029..8093
                     /gene="proW"
                     /locus_tag="RH288_000009"
     CDS             7029..8093
                     /gene="proW"
                     /locus_tag="RH288_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HDV4029122.1"
                     /translation="MADQNNPWDTTPAADSAAQSADAWGTPTTAPTDGGGADWLTSTP
                     APNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLL
                     GMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
                     VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLLTRPFIK"
     gene            8151..9143
                     /gene="proX"
                     /locus_tag="RH288_000010"
     CDS             8151..9143
                     /gene="proX"
                     /locus_tag="RH288_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HDV4029123.1"
                     /translation="MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKK
                     FYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
                     WGCEGAINHQLAAYELTNTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNEL
                     KPGKDVVWLQVPFSALPGDKNADTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLF
                     AIMQLPVADINAQNAIMHDGKASEGDIQGHVDGWIKAHQQQFDGWVNEALAAQK"
     gene            9335..10519
                     /locus_tag="RH288_000011"
     CDS             9335..10519
                     /locus_tag="RH288_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4029124.1"
                     /translation="MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAACGMLITASSQSLAMM
                     ILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISDKILRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKS
                     HHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEA
                     AN"
     gene            10643..11380
                     /gene="ygaZ"
                     /locus_tag="RH288_000012"
     CDS             10643..11380
                     /gene="ygaZ"
                     /locus_tag="RH288_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine exporter subunit YgaZ"
                     /protein_id="HDV4029125.1"
                     /translation="MESPTPQPAPGSATFMEGCKDSLPIVISYIPVAFAFGLNATRLG
                     FSPLESVFFSCIIYAGASQFVITAMLAAGSSLWIAALTVMAMDVRHVLYGPSLRSRII
                     QRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGA
                     FSGSGLLQGYPAVEAALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIP
                     VAILAGIVCGCLTALIQAFWQGAPDEL"
     gene            11370..11705
                     /gene="ygaH"
                     /locus_tag="RH288_000013"
     CDS             11370..11705
                     /gene="ygaH"
                     /locus_tag="RH288_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine transporter subunit YgaH"
                     /protein_id="HDV4029126.1"
                     /translation="MSYEVLLLGLLVGVANYCFRYLPLRLRVGNARPTKRGAVGILLD
                     TIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGASFYKTRSIIIPTLLSALAYG
                     LAWKVMAII"
     gene            11796..12326
                     /gene="emrR"
                     /locus_tag="RH288_000014"
     CDS             11796..12326
                     /gene="emrR"
                     /locus_tag="RH288_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter EmrAB
                     transcriptional repressor EmrR"
                     /protein_id="HDV4029127.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
                     RLDQMEQDGVVLEAMS"
     gene            12453..13625
                     /gene="emrA"
                     /locus_tag="RH288_000015"
     CDS             12453..13625
                     /gene="emrA"
                     /locus_tag="RH288_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HDV4029128.1"
                     /translation="MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFL
                     VLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFE
                     KAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
                     QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRI
                     ISPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYP
                     LRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG"
     gene            13642..15180
                     /gene="emrB"
                     /locus_tag="RH288_000016"
     CDS             13642..15180
                     /gene="emrB"
                     /locus_tag="RH288_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HDV4029129.1"
                     /translation="MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSL
                     NMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQI
                     MLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESMHHAQLTESVNPFNPNAQAMYSQL
                     EGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(15244..15759)
                     /gene="luxS"
                     /locus_tag="RH288_000017"
     CDS             complement(15244..15759)
                     /gene="luxS"
                     /locus_tag="RH288_000017"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDV4029130.1"
                     /translation="MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPN
                     KEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
                     LPKEKLQELHI"
     gene            complement(15909..17465)
                     /gene="gshA"
                     /locus_tag="RH288_000018"
     CDS             complement(15909..17465)
                     /gene="gshA"
                     /locus_tag="RH288_000018"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HDV4029131.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPF
                     EKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAK
                     IGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLG
                     IGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
                     ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTE
                     PFAVWLEKHA"
     gene            complement(17538..17966)
                     /locus_tag="RH288_000019"
     CDS             complement(17538..17966)
                     /locus_tag="RH288_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV4029132.1"
                     /translation="MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGISHPWVLV
                     LTATMGNSLGGLTNVILGRFFPLRKTSRWQEKATGWLKRYGAVTLLLSWMPVVGDLLC
                     LLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH"
     gene            complement(17963..18529)
                     /gene="yqaB"
                     /locus_tag="RH288_000020"
     CDS             complement(17963..18529)
                     /gene="yqaB"
                     /locus_tag="RH288_000020"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HDV4029133.1"
                     /translation="MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDIQAMI
                     ALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVRSMLLDSVEPLPLVDVVKSWHGR
                     RPMAVGTGSESAIAEALLAHLGLRHYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
                     QCVVFEDADFGIQAARAAGMDAVDVRLL"
     gene            complement(18810..18886)
                     /locus_tag="RH288_000021"
     tRNA            complement(18810..18886)
                     /locus_tag="RH288_000021"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18850..18852),aa:Arg,seq:acg)
     gene            complement(19085..19161)
                     /locus_tag="RH288_000022"
     tRNA            complement(19085..19161)
                     /locus_tag="RH288_000022"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19125..19127),aa:Arg,seq:acg)
     gene            complement(19224..19300)
                     /locus_tag="RH288_000023"
     tRNA            complement(19224..19300)
                     /locus_tag="RH288_000023"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19264..19266),aa:Arg,seq:acg)
     gene            complement(19499..19575)
                     /locus_tag="RH288_000024"
     tRNA            complement(19499..19575)
                     /locus_tag="RH288_000024"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19539..19541),aa:Arg,seq:acg)
     gene            complement(19579..19671)
                     /locus_tag="RH288_000025"
     tRNA            complement(19579..19671)
                     /locus_tag="RH288_000025"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19635..19637),aa:Ser,seq:gct)
     gene            complement(19987..20172)
                     /gene="csrA"
                     /locus_tag="RH288_000026"
     CDS             complement(19987..20172)
                     /gene="csrA"
                     /locus_tag="RH288_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDV4029134.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(20407..23037)
                     /gene="alaS"
                     /locus_tag="RH288_000027"
     CDS             complement(20407..23037)
                     /gene="alaS"
                     /locus_tag="RH288_000027"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDV4029135.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDL
                     SNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNTQIRRNL
                     PIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTR
                     QLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLG
                     STIIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVKGWVSAKLQ"
     gene            complement(23165..23665)
                     /gene="recX"
                     /locus_tag="RH288_000028"
     CDS             complement(23165..23665)
                     /gene="recX"
                     /locus_tag="RH288_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDV4029136.1"
                     /translation="MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKN
                     GPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGIS
                     REATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQEI
                     WRNFAD"
     gene            complement(23734..24795)
                     /gene="recA"
                     /locus_tag="RH288_000029"
     CDS             complement(23734..24795)
                     /gene="recA"
                     /locus_tag="RH288_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDV4029137.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     IYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNS
                     TPDFSVDDSEGVAETNEDF"
     gene            complement(24875..25372)
                     /gene="pncC"
                     /locus_tag="RH288_000030"
     CDS             complement(24875..25372)
                     /gene="pncC"
                     /locus_tag="RH288_000030"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HDV4029138.1"
                     /translation="MTDSELMQLSEQVGQALKARGATVTTAESCTGGWVAKVITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSEPVVVEMAIGALKAARADYAVSI
                     SGIAGPDGGSEEKPVGTVWFAFATARGEGITRRECFSGDRDAVRRQATAYALQTLWQQ
                     FLQNT"
     gene            complement(25517..26602)
                     /gene="mltB"
                     /locus_tag="RH288_000031"
     CDS             complement(25517..26602)
                     /gene="mltB"
                     /locus_tag="RH288_000031"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HDV4029139.1"
                     /translation="MFKRRYVTLLPLFVLLAACSSKPKPTETDTTTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTT
                     SVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
                     VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFA
                     GAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMAN
                     GQAPGLPNGFKTKYSISQLAAAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYT
                     ITRYNHSTHYAMAVWQLGQAVALTRVQ"
     gene            26858..27421
                     /gene="srlA"
                     /locus_tag="RH288_000032"
                     /gene_synonym="gutA"
     CDS             26858..27421
                     /gene="srlA"
                     /locus_tag="RH288_000032"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDV4029140.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQHRIERFAQRCAGNPVSRYLLLPCIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLNLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVHLAGATS"
     gene            27418..28377
                     /gene="srlE"
                     /locus_tag="RH288_000033"
                     /gene_synonym="gutE"
     CDS             27418..28377
                     /gene="srlE"
                     /locus_tag="RH288_000033"
                     /gene_synonym="gutE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDV4029141.1"
                     /translation="MTHIRIEKGTGGWGGPLELKATPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITVVGDATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSTVA
                     VLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLA
                     LICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPV
                     GLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ"
     gene            28388..28759
                     /gene="srlB"
                     /locus_tag="RH288_000034"
                     /gene_synonym="gutB"
     CDS             28388..28759
                     /gene="srlB"
                     /locus_tag="RH288_000034"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDV4029142.1"
                     /translation="MTVIYQTTITRIGASAIDALSDQMLITFREGAPADLEEYCFIHC
                     HGELKGALHPGLQFSLGQHRYPVTAVGSVAEDNLRELGHVTLRFDGLNEAEFPGTVHV
                     AGPVPDDIAPGSVLKFESVKE"
     gene            28763..29542
                     /gene="srlD"
                     /locus_tag="RH288_000035"
     CDS             28763..29542
                     /gene="srlD"
                     /locus_tag="RH288_000035"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDV4029143.1"
                     /translation="MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQ
                     EINAEYGESMAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            29647..30006
                     /gene="gutM"
                     /locus_tag="RH288_000036"
     CDS             29647..30006
                     /gene="gutM"
                     /locus_tag="RH288_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDV4029144.1"
                     /translation="MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGR
                     SSGRFKPRVVVAIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPH
                     DPLSQNALSLALKLKRG"
     gene            30073..30846
                     /gene="srlR"
                     /locus_tag="RH288_000037"
                     /gene_synonym="gutR"
     CDS             30073..30846
                     /gene="srlR"
                     /locus_tag="RH288_000037"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HDV4029145.1"
                     /translation="MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     HAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIILDAGST
                     VLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNV
                     VCSLESVDKLITDAGIDPAFRQALEEKGIDVIITGESNE"
     gene            30839..31804
                     /gene="gutQ"
                     /locus_tag="RH288_000038"
     CDS             30839..31804
                     /gene="gutQ"
                     /locus_tag="RH288_000038"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HDV4029146.1"
                     /translation="MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGK
                     VVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASV
                     MDAMLELSRTGLGLVAVCDAQQQVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTL
                     QSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(31801..33315)
                     /gene="norR"
                     /locus_tag="RH288_000039"
     CDS             complement(31801..33315)
                     /gene="norR"
                     /locus_tag="RH288_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417189.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HDV4029147.1"
                     /translation="MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALL
                     RYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
                     LLIEQLESQNMLPGDATPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETG
                     TGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRCLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRQGLSRVVLSAGAR
                     NLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPTPEVAAVP
                     VVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD"
     gene            33502..34941
                     /gene="norV"
                     /locus_tag="RH288_000040"
     CDS             33502..34941
                     /gene="norV"
                     /locus_tag="RH288_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HDV4029148.1"
                     /translation="MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     AETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREI
                     ARQWALAPLPQSTVNSVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGT
                     PWSEVPDNFLCPECSLGKDVFDELASEAK"
     gene            34938..36071
                     /gene="norW"
                     /locus_tag="RH288_000041"
     CDS             34938..36071
                     /gene="norW"
                     /locus_tag="RH288_000041"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HDV4029149.1"
                     /translation="MSNGIVIIGSGFAARQLVKNIRKQDATIPLTLIAADSMDEYNKP
                     DISHVISQGQRADDLTRQTAGEFAEQFNLHLFPQTWVTDIDAEARVVKSQNNQWQYDK
                     LVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
                     CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGIQA
                     TLDRQRNIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNTDIYALGDCAE
                     INGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLR
                     WQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM"
     gene            complement(36199..38451)
                     /gene="hypF"
                     /locus_tag="RH288_000042"
     CDS             complement(36199..38451)
                     /gene="hypF"
                     /locus_tag="RH288_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HDV4029150.1"
                     /translation="MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD
                     GVEVRLREDPETFLVQLYQHCPPLARIDSVEREPFIWSQLPTEFTIRQSTGGTMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ACDKEYRDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGKIVAI
                     KGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIV
                     LVDKKYVPELCDDIAPDLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISN
                     EQALADLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALALPPGFKNVP
                     PVLCLGADLKNTFCLVRGEQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVV
                     HDAHPGYVSSQWAREMNLPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALAGGDLAAKQPWRNLLAQCLRFVPEWQNYPE
                     TASVQQQNWSVLARAIERGINAPLASSCGRFFDAVAAALGCAPATLSYEGEAACALEA
                     LAASCHGVTHPVTMPRVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMRE
                     QATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAA
                     RWLAGEVQNG"
     gene            complement(38604..39131)
                     /gene="hydN"
                     /locus_tag="RH288_000043"
     CDS             complement(38604..39131)
                     /gene="hydN"
                     /locus_tag="RH288_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HDV4029151.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRTALMF"
     gene            complement(39280..40290)
                     /gene="ascG"
                     /locus_tag="RH288_000044"
     CDS             complement(39280..40290)
                     /gene="ascG"
                     /locus_tag="RH288_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator AscG"
                     /protein_id="HDV4029152.1"
                     /translation="MTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEESG
                     YRPNLLARNLSAKSTQTLGLVVTNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKHS
                     AEEERQAIQYLLDLRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRKNSSHSVW
                     CDHKQTSFNAVAELINAGHQEIAFLTGSMDSPTSIERLAGYKDALAQHGIALNEKLIA
                     NGKWTPASGAEGVEMLLERGAKFSALVASNDDMAIGAMKALHERGVAVPEQVSVIGFD
                     DIAIAPYTVPALSSVKIPVTEMIQEIIGRLIFMLDGGDFSPPKTFSGKLIRRDSLIAP
                     SR"
     gene            40550..42006
                     /gene="ascF"
                     /locus_tag="RH288_000045"
                     /pseudo
     CDS             40550..42006
                     /gene="ascF"
                     /locus_tag="RH288_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026182.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose/arbutin/salicin transporter
                     subunit IIBC"
     gene            42015..43439
                     /gene="ascB"
                     /locus_tag="RH288_000046"
     CDS             42015..43439
                     /gene="ascB"
                     /locus_tag="RH288_000046"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase AscB"
                     /protein_id="HDV4029153.1"
                     /translation="MSVFPESFLWGGALAANQSEGAFREGDKGLTTVDMIPHGEHRMA
                     VKLGLEKRFQLRDDEFYPSHEATDFYHRYKEDIALMAEMGFKVFRTSIAWSRLFPQGD
                     EITPNQQGIAFYRSVFEECKKYGIEPLVTLCHFDVPMHLVTEYGSWRNRKLVEFFSRY
                     ARTCFEAFDGLVKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLVASA
                     LATKIAHEVNPQNQVGCMLAGGNFYPYSCKPEDVWAALEKDRENLFFIDVQARGTYPA
                     YSARVFREKGVTINKAPGDDEILKNTVDFVSFSYYASRCASAEMNANNSSAANVVKSL
                     RNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGAKDEFAANGEINDDYR
                     ISYLREHIRAMGEAIADGIPLMGYTTWGCIDLVSASTGEMSKRYGFVFVDRDDAGNGT
                     LTRTRKKSFWWYKKVIASNGEDLE"
     gene            complement(43598..44068)
                     /gene="hycI"
                     /locus_tag="RH288_000047"
     CDS             complement(43598..44068)
                     /gene="hycI"
                     /locus_tag="RH288_000047"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HDV4029154.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPE
                     NDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDQLK
                     EDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWERNGGFAQLAVEEE"
     gene            complement(44061..44471)
                     /gene="hycH"
                     /locus_tag="RH288_000048"
     CDS             complement(44061..44471)
                     /gene="hycH"
                     /locus_tag="RH288_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase assembly protein HycH"
                     /protein_id="HDV4029155.1"
                     /translation="MSEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDEYLAWIATLEAGSEARRKMEGVPKYGEIVIDINHVPMLANAFDKARAA
                     QTSQQQEWSTMLLSMLHDIHQENAIYLMVRRLRD"
     gene            complement(44468..45235)
                     /gene="hycG"
                     /locus_tag="RH288_000049"
     CDS             complement(44468..45235)
                     /gene="hycG"
                     /locus_tag="RH288_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HDV4029156.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARGPGELDEQPAEILHGDMVQPLRVKVDREARRLAGYRYGRQIADDYLTQ
                     LGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR"
     gene            complement(45235..45777)
                     /gene="hycF"
                     /locus_tag="RH288_000050"
     CDS             complement(45235..45777)
                     /gene="hycF"
                     /locus_tag="RH288_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HDV4029157.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCA
                     ACVNACPSNALTVETDLATGELAWEFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
                     QKCLVPSDRIELTRHMKEAI"
     gene            complement(45787..47496)
                     /gene="hycE"
                     /locus_tag="RH288_000051"
     CDS             complement(45787..47496)
                     /gene="hycE"
                     /locus_tag="RH288_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HDV4029158.1"
                     /translation="MSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPE
                     VVEFLYYKQGGWLSVLFGNDERKLNGHYAVYYVLSMEKGTKCWITVRVEVDANKPEYP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            complement(47514..48437)
                     /gene="hycD"
                     /locus_tag="RH288_000052"
     CDS             complement(47514..48437)
                     /gene="hycD"
                     /locus_tag="RH288_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycD"
                     /protein_id="HDV4029159.1"
                     /translation="MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIFKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIATALPVVTVGSPLPQLGDLITLLY
                     LFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVAGSTNISNI
                     TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFG
                     VMKWGISLKQLVVLQMFVGVFIPWGQMETFTAGGLLLALVIAIVKLVVGVLVIALFEN
                     SMARLRLDITPRITWAGFGFAFLAFVSLLAA"
     gene            complement(48440..50266)
                     /gene="hycC"
                     /locus_tag="RH288_000053"
     CDS             complement(48440..50266)
                     /gene="hycC"
                     /locus_tag="RH288_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HDV4029160.1"
                     /translation="MSAISLINSGVAWFVAAAVLAFLFSFQKALSGWIAGIGGAVGSL
                     YTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIWLITLGLCGLFVSLYNIDWHRHA
                     QVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEIMALCAVFLTSNSKEGKLWFALGRL
                     GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILTLSLLGGNAPLWWGIALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIALGLVGGLYHLLNHSL
                     FKSVLFLGAGSIWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ATCAPLLMSVSVVALAICCVIGGVAAPWLLPMLSAAVPLPLEPANTTVSQPMITLLLI
                     ACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAFAPVLKL
                     RKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA"
     gene            complement(50263..50874)
                     /gene="hycB"
                     /locus_tag="RH288_000054"
     CDS             complement(50263..50874)
                     /gene="hycB"
                     /locus_tag="RH288_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HDV4029161.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEK
                     ESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLDIPANANTPKAPPAPPAPARVSTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK"
     gene            complement(50999..51460)
                     /gene="hycA"
                     /locus_tag="RH288_000055"
     CDS             complement(50999..51460)
                     /gene="hycA"
                     /locus_tag="RH288_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HDV4029162.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGM
                     IDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPAA"
     gene            51672..52022
                     /gene="hypA"
                     /locus_tag="RH288_000056"
     CDS             51672..52022
                     /gene="hypA"
                     /locus_tag="RH288_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HDV4029163.1"
                     /translation="MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSL
                     AFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVA
                     DDGLQIRRIEIDQE"
     gene            52026..52898
                     /gene="hypB"
                     /locus_tag="RH288_000057"
     CDS             52026..52898
                     /gene="hypB"
                     /locus_tag="RH288_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HDV4029164.1"
                     /translation="MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIK
                     APEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     KQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIACAREVNPEIEIILISATSGEG
                     MDQWLNWLETQRCA"
     gene            52889..53161
                     /gene="hypC"
                     /locus_tag="RH288_000058"
     CDS             52889..53161
                     /gene="hypC"
                     /locus_tag="RH288_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HDV4029165.1"
                     /translation="MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRV
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEEK"
     gene            53161..54282
                     /gene="hypD"
                     /locus_tag="RH288_000059"
     CDS             53161..54282
                     /gene="hypD"
                     /locus_tag="RH288_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HDV4029166.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
                     AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPH
                     QCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQENEA"
     gene            54279..55289
                     /gene="hypE"
                     /locus_tag="RH288_000060"
     CDS             54279..55289
                     /gene="hypE"
                     /locus_tag="RH288_000060"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation carbamoyl dehydratase
                     HypE"
                     /protein_id="HDV4029167.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLA
                     QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKAVVTSMAETARTAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWG
                     AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKA
                     LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLV
                     IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            55363..57441
                     /gene="flhA"
                     /locus_tag="RH288_000061"
     CDS             55363..57441
                     /gene="flhA"
                     /locus_tag="RH288_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HDV4029168.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALA
                     DNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLAHGPVRSILSRPDTLHCSYEEFC
                     ETWPQLAAGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
                     SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYF
                     DIDDISIVLRSHRKNKLNIYSTHYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     HERDDLAPYERMLFDTWGNQIQTLCLLPLMSGDTMLGVLKLAQCEEKVFTTTNLNLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVL
                     KQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAF
                     TFKIARRLGRNIDSIPAETLRTLSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDI
                     VLPEPETPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMK
                     RLGIDKSALI"
     gene            complement(57478..57831)
                     /locus_tag="RH288_000062"
     CDS             complement(57478..57831)
                     /locus_tag="RH288_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HDV4029169.1"
                     /translation="MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYEALFVYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPILTVRHLIDDKRP
                     VPELPEKYRPKKPHE"
     gene            complement(57863..58042)
                     /locus_tag="RH288_000063"
     CDS             complement(57863..58042)
                     /locus_tag="RH288_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001363568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029170.1"
                     /translation="MIPELIISGEEANGEFLMLVPGKMLFCSFCVMLMKQVRKIASVG
                     EPFFFRVIVPFKIKM"
     gene            58118..60679
                     /gene="mutS"
                     /locus_tag="RH288_000064"
     CDS             58118..60679
                     /gene="mutS"
                     /locus_tag="RH288_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDV4029171.1"
                     /translation="MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDA
                     KRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATS
                     KGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
                     ADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFG
                     TRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRN
                     LEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDF
                     TAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQA
                     LREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERL
                     EVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKE
                     YEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLN
                     YTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYM
                     RQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH
                     NATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKME
                     GVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
                     ISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            60785..61441
                     /gene="pphB"
                     /locus_tag="RH288_000065"
     CDS             60785..61441
                     /gene="pphB"
                     /locus_tag="RH288_000065"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HDV4029172.1"
                     /translation="MPSTRYQKINAHHYRHIWVVGDIHGEYQLLQSRLHQLSFFPEID
                     LLISVGDNIDRGPESLDVLRLLNQPWFTSVKGNHEAMALEAFETGDGNMWLASGGDWF
                     FDLNDSEQQEAIDLLLKFHHLPHIIEITNDNIKYAIAHADYPGSEYLFGKEIAESELL
                     WPVDRVQKSLNGELQQINGADYFIFGHMMFDNIQTFANQIYIDTGSPNSGRLSFYKIK
                     "
     gene            complement(61492..62259)
                     /locus_tag="RH288_000066"
     CDS             complement(61492..62259)
                     /locus_tag="RH288_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV4029173.1"
                     /translation="MIPVERRQIILEMVAEKGIVSIAELTDRMNVSHMTIRRDLQKLE
                     QQGAVVLVSGGVQSPGRVAHEPSHQVKTALAMTQKAAIGKLAASLVQPGSCIYLDAGT
                     TTLAIAQHLIHMESLTVVTNDFVIADYLLDNSNCTIIHTGGAVCRENRSCVGEAAATM
                     LRSLMIDQAFISASSWSVRGISTPAEDKVTVKRAIASASRQRVLVCDATKYGQVATWL
                     ALPLSEFDQIITDDGLPESASRALVKQDLSLLVAKNE"
     gene            62455..63363
                     /locus_tag="RH288_000067"
     CDS             62455..63363
                     /locus_tag="RH288_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDV4029174.1"
                     /translation="MKTGSEFHVGIVGLGSMGMGAALSCVRAGLSTWGADLNSNACAT
                     LKEAGACGVSDNAATFAEKLDALLVLVVNAAQVKQVLFGETGVAQHLKPGTAVMVSST
                     IASADAQEIATALAGFDLEMLDAPVSGGAVKAANGEMTVMASGSDIAFERLAPVLEAV
                     AGKVYRIGAEPGLGSTVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTNAAG
                     NSWMFENRMRHVVDGDYTPHSAVDIFVKDLGLVADTAKALHFPLPLASTALNMFTSAS
                     NAGYGKEDDSAVIKIFSGITLPGAKS"
     gene            63360..64622
                     /locus_tag="RH288_000068"
     CDS             63360..64622
                     /locus_tag="RH288_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HDV4029175.1"
                     /translation="MIKIGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAID
                     ALVISLKTRSCPVVEATQQSLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDAL
                     MDALDTPFTVFSPALPVNGRTVYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEA
                     QSTGRCGVVSAHVFEQGVDAVRQELARLQQEGYRYAVLDALTEHHLEIQGEALRDAPL
                     VTGGSGLAIGLARQWAQENGNQARKAGRPLAGRGVVLSGSCSQMTNRQVAHYRQIAPA
                     REVDVARCLSIETLAAYAHELAEWVLGQESVLAPLVFATASTDALAAIQQQYGAQKAS
                     QAVETLFSQLAARLAAEGVTRFIVAGGETSGVVTQSLGIKGFHIGPTISPGVPWVNAL
                     DKPVSLALKSGNFGDDAFFSRAQREFLS"
     gene            64619..65257
                     /locus_tag="RH288_000069"
     CDS             64619..65257
                     /locus_tag="RH288_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDV4029176.1"
                     /translation="MSDFAKVEQSLREEMTRIASSFFQRGYATGSAGNLSLLLPDGNL
                     LATPTGSCLGNLDPQRLSKVAADGEWLSGDKPSKEVLFHLALYRNNPRCKAVVHLHST
                     WSTALSCLQGLDSSNVIRPFTPYVVMRMGNVPLVPYYRPGDKRIAQDLAELAADNQAF
                     LLANHGPVVCGESLQEAANNMEELEETAKLIFILGDRPIRYLTAGEIAELRS"
     gene            65262..66038
                     /locus_tag="RH288_000070"
     CDS             65262..66038
                     /locus_tag="RH288_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDV4029177.1"
                     /translation="MPRFAANLSMMFTEVPFIERFAAARKAGFDAVEFLFPYNYSTLQ
                     IQKQLEQNHLTLALFNTAPGDINAGEWGLSALPGREHEAHADIDLALEYALALNCEQV
                     HVMAGVVPAGEDAERYRAVFIDNIRYAADRFAPHGKRILVEALSPGVKPHYLFSSQYQ
                     ALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRDYAGKYAHVQIAGLPDRHEPDDGE
                     INYPWLFRLFDEVGYQGWIGCEYKPRGLTEEGLGWFDAWR"
     gene            66127..67491
                     /locus_tag="RH288_000071"
     CDS             66127..67491
                     /locus_tag="RH288_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family transporter"
                     /protein_id="HDV4029178.1"
                     /translation="MSTITLLCIALAGVIMLLLLVIKAKVQPFVALLLVSLLVALAAG
                     IPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSGGAESLANYFSRKLGDKRTI
                     AALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPP
                     HPGPVAAAGLLHADIGWLTIIGIAISIPVGVVGYFAAKIINKRQYAMSVEVLEQMQLA
                     PASEEGATKLSDKINPPGVALVTSLIVIPIAIIMAGTVSATLMPPSHPLLGTLQLIGS
                     PMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAVVILVTGAGGVFGKVLVES
                     GVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLSEAVMGLNPIQC
                     VLVTLAACFGGLGASHINDSGFWIVTKYLGLSVADGLKTWTVLTTILGFTGFLITWCV
                     WAVI"
     gene            complement(67585..68577)
                     /gene="rpoS"
                     /locus_tag="RH288_000072"
     CDS             complement(67585..68577)
                     /gene="rpoS"
                     /locus_tag="RH288_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HDV4029179.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(68640..69779)
                     /gene="nlpD"
                     /locus_tag="RH288_000073"
     CDS             complement(68640..69779)
                     /gene="nlpD"
                     /locus_tag="RH288_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HDV4029180.1"
                     /translation="MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAP
                     ANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENG
                     RIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
                     QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSA
                     NKMLPNNKPTATTVTAPVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASE
                     GGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLV
                     REQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            complement(69919..70545)
                     /gene="pcm"
                     /locus_tag="RH288_000074"
     CDS             complement(69919..70545)
                     /gene="pcm"
                     /locus_tag="RH288_000074"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HDV4029181.1"
                     /translation="MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKA
                     WDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCS
                     VERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
                     QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            complement(70539..71300)
                     /gene="surE"
                     /locus_tag="RH288_000075"
     CDS             complement(70539..71300)
                     /gene="surE"
                     /locus_tag="RH288_000075"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HDV4029182.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
                     PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVD
                     EGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW"
     gene            complement(71281..72330)
                     /gene="truD"
                     /locus_tag="RH288_000076"
     CDS             complement(71281..72330)
                     /gene="truD"
                     /locus_tag="RH288_000076"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HDV4029183.1"
                     /translation="MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHI
                     LVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLS
                     AFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
                     GAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQ
                     VVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQ
                     AAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVV
                     RELINTTGDYAHIAE"
     gene            complement(72327..72806)
                     /gene="ispF"
                     /locus_tag="RH288_000077"
     CDS             complement(72327..72806)
                     /gene="ispF"
                     /locus_tag="RH288_000077"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDV4029184.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK"
     gene            complement(72806..73516)
                     /gene="ispD"
                     /locus_tag="RH288_000078"
     CDS             complement(72806..73516)
                     /gene="ispD"
                     /locus_tag="RH288_000078"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDV4029185.1"
                     /translation="MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHA
                     LLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWV
                     LVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQENT"
     gene            complement(73535..73846)
                     /gene="ftsB"
                     /locus_tag="RH288_000079"
     CDS             complement(73535..73846)
                     /gene="ftsB"
                     /locus_tag="RH288_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HDV4029186.1"
                     /translation="MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNA
                     KLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNN
                     R"
     gene            complement(74040..74363)
                     /locus_tag="RH288_000080"
     CDS             complement(74040..74363)
                     /locus_tag="RH288_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HDV4029187.1"
                     /translation="MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPML
                     IYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALF
                     MWLLG"
     gene            complement(74413..75018)
                     /gene="cysC"
                     /locus_tag="RH288_000081"
     CDS             complement(74413..75018)
                     /gene="cysC"
                     /locus_tag="RH288_000081"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HDV4029188.1"
                     /translation="MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLV
                     VLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
                     GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS"
     gene            complement(75018..76445)
                     /gene="cysN"
                     /locus_tag="RH288_000082"
     CDS             complement(75018..76445)
                     /gene="cysN"
                     /locus_tag="RH288_000082"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HDV4029189.1"
                     /translation="MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSE
                     SMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQ
                     RVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAV
                     QSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNG
                     IGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSA
                     FELELNALVRRHFPHWGARDLLGDK"
     gene            complement(76447..77355)
                     /gene="cysD"
                     /locus_tag="RH288_000083"
     CDS             complement(76447..77355)
                     /gene="cysD"
                     /locus_tag="RH288_000083"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HDV4029190.1"
                     /translation="MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST
                     TSERQGRVIDRDQAGSMELKKRQGYF"
     gene            77607..78644
                     /gene="iap"
                     /locus_tag="RH288_000084"
     CDS             77607..78644
                     /gene="iap"
                     /locus_tag="RH288_000084"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase isozyme conversion
                     aminopeptidase"
                     /protein_id="HDV4029191.1"
                     /translation="MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFF
                     PGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIA
                     AHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
                     TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGV
                     KTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSV
                     EATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIM
                     LPLVKELAKAS"
     repeat_region   78727..79547
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=78788..78816
                     /rpt_unit_seq="cggtttatccccgctggcgcggggaacac"
     gene            complement(79644..79937)
                     /gene="cas2"
                     /locus_tag="RH288_000085"
     CDS             complement(79644..79937)
                     /gene="cas2"
                     /locus_tag="RH288_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2"
                     /protein_id="HDV4029192.1"
                     /translation="MSMIVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIW
                     QQISQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ"
     gene            complement(79934..80857)
                     /gene="cas1e"
                     /locus_tag="RH288_000086"
     CDS             complement(79934..80857)
                     /gene="cas1e"
                     /locus_tag="RH288_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endonuclease Cas1"
                     /protein_id="HDV4029193.1"
                     /translation="MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHI
                     PVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQ
                     AKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKW
                     NGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYD
                     IADIIKFDLVVPKAFEIAARQPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGE
                     IEPPQPAPDMLPPAIPEPETLGDSGHRGRGG"
     gene            complement(80854..81504)
                     /gene="cas6e"
                     /locus_tag="RH288_000087"
     CDS             complement(80854..81504)
                     /gene="cas6e"
                     /locus_tag="RH288_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="HDV4029194.1"
                     /translation="MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQ
                     FLYRREELQGAFRFFVLSQERPAESETFTIECRSFTPELSTGQQLCFNLRANPTICKA
                     GKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQ
                     LRRENSWQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA"
     gene            complement(81486..82232)
                     /gene="cas5e"
                     /locus_tag="RH288_000088"
     CDS             complement(81486..82232)
                     /gene="cas5e"
                     /locus_tag="RH288_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="HDV4029195.1"
                     /translation="MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGV
                     GIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPE
                     LLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPL
                     APLLLEGNASDVLRNAYQQYQDRFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDV
                     PLNRQQWLFGERTINQGPWLSKEEPCTSQE"
     gene            complement(82243..83298)
                     /gene="cas7e"
                     /locus_tag="RH288_000089"
     CDS             complement(82243..83298)
                     /gene="cas7e"
                     /locus_tag="RH288_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="HDV4029196.1"
                     /translation="MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSL
                     KRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAK
                     NDKKPKDPLTNAETEQLVHISPAEFDAVKVLAHQLAEEKRAPKEEDLALLRKDRMAVD
                     IAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGE
                     TGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAY
                     ASWALAEKGTDQPRSLAAAFYEPINGTRQLEVAVQRITTLRENMNTVYEQKTDYASFD
                     VMNKQGSMKDVLDFICA"
     gene            complement(83310..83846)
                     /gene="casB"
                     /locus_tag="RH288_000090"
     CDS             complement(83310..83846)
                     /gene="casB"
                     /locus_tag="RH288_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="HDV4029197.1"
                     /translation="MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGF
                     RLFLKNRQIKWQDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLS
                     AVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRI
                     RWALEYYQAGDADNEQNQ"
     gene            complement(83843..85405)
                     /gene="casA"
                     /locus_tag="RH288_000091"
     CDS             complement(83843..85405)
                     /gene="casA"
                     /locus_tag="RH288_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="HDV4029198.1"
                     /translation="MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDISAPRADL
                     QGAVWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALQSLEHAFQFGPDSPSFM
                     QDFEALTGDKVPVASLLPEIPGAQTTKFNKDHFIKRGVTEYLCPHCSALALFSLQLNA
                     PSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWINVMPQDEADLPLPKKFDD
                     LVFPWLGPTRTSELAGAVVTDEQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDA
                     LLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKS
                     ENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLDKKEGQIP
                     KLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIE
                     EGQDADELLSKWNKEIWLFARQDFDERVFTNPYEPVDLERVMTARKKYFTTSAEKQSA
                     KAAREKKQEAAE"
     gene            complement(85503..88160)
                     /gene="cas3"
                     /locus_tag="RH288_000092"
     CDS             complement(85503..88160)
                     /gene="cas3"
                     /locus_tag="RH288_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001674509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
                     /protein_id="HDV4029199.1"
                     /translation="MTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCF
                     GLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEK
                     ISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGRPPDRMDELD
                     NFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGS
                     STRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQ
                     QKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANA
                     MYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGC
                     AAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYM
                     SCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWL
                     THVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDA
                     IKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRSSQVIVCTQ
                     VIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPKLLILA
                     PVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGE
                     DVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESV
                     SLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQ
                     DPEMANVILVNDDESCGYSATEGLIGKVG"
BASE COUNT        20835 a        23872 c        22575 g        20888 t
ORIGIN      
        1 aatgtacaaa aaacgagccg ttacggaata ttttatctac aaaaactgac taaataaaaa
       61 tttttcacta attgattagt catagccagc gatatacgct atgcgaaaat gcagatggca
      121 atgagatcca ctgctttcat ctccattaac atcccattac gcttttatta aggagcatta
      181 gcatgttctc accgcagtca cgcttgcgtc atgcagttgc agatacgttc gcgatggttg
      241 tttactgttc tgtcgtgaac atgtgtattg aagttttcct ctccggaatg agcttcgaac
      301 agtcttttta ttccagattg gtagcgattc cggtgaacat cttaattgca tggccatacg
      361 gtatgtaccg tgatctgttt atgcgcgcgg cacgcaaagt tagcccgtcg ggctggataa
      421 aaaatctggc ggatatcctg gcttatgtga cgttccagtc accggtgtat gtggcgatct
      481 tgttagtggt gggcgcagac tggcatcaga ttatggcggc ggtcagttca aacatcgttg
      541 tttcgatgtt gatgggggcg gtttatggct acttcctcga ttattgccgc cgactgttta
      601 aagtcagccg ttaccagcag gtaaaagcct gactcttctt ttcgcgactg gcatcgccag
      661 tcgcgtcttt aactggcttc gccaaataaa ccattcaaat aacgttcaag cgcaacacgc
      721 gaactaaagc catgcgggat accgtaatgc tcgtgtcgct cgcctgctaa atagagcgga
      781 aattgctggt aatgatcgca agttttaata tcggaagcgg gttcagccag tgtcgaactg
      841 cgttctttta atgttggatg aattaccaga gcggtacgtc ccattcgcgc ttcgcgatta
      901 acatagacat aattttcccc acggcggtaa ccatacgctt tctgggttac cacatcgaca
      961 gtaaaaccga ctttttcaag tacgcgcgcc acctcgtctg gtcgtaaata catatttgat
     1021 cctcgttatt atcaaccgcg ggcctacctt acctgattgc gcattcacaa cgctttcaga
     1081 aaagtccata aagccgcgat gaacctcagt taagaaaatt atggtctaca ctgaaaatta
     1141 catcgaattc taatggggga tcatatgttt aaccgaccga accgcaacga cgttgatgat
     1201 ggcgtgcagg atatccagaa tgatgtcaat caattagctg acagcctcga atctgtattg
     1261 aagtcctggg gcagcgacgc caaaggggaa gctgaagccg cacgcagtaa agctcaggca
     1321 ttgctgaaag aaaccagggc gcgaatgcat ggtcgtactc gcgtccagca agccgcgcgc
     1381 gatgccgttg gctgcgcgga ttcttttgtt cgtgaaagac cctggtgtag cgtgggtaca
     1441 gcagctgcgg taggtatttt tatcggcgca ctgttaagca tgcgcaaatc gtagtgcaaa
     1501 aatgataata aatacgcgtc tttgaccccg aagcctgtct tcggggtttc tttttgcctg
     1561 gtgaatcaca aaaatccccc taccccgtca cgctcatatc cagggtaatt tcgaccacta
     1621 tttgctatat attgtgtggt tgaatctttt ttcaactaca tctagtatct ctgtatcaac
     1681 agagagacaa cccgacgcgt atcatcgcgc cgtatcttca ttttaaacgg aaatacgaat
     1741 catgcgcatt actatttaca ctcgtaacga ttgcgttcag tgccacgcca ccaaacgggc
     1801 gatggaaaac cggggctttg attttgaaat gattaatgtc gatcgcgttc ctgaagcggc
     1861 agaagcgttg cgtgctcagg gctttcgtca gttgccggta gtgattgctg gcgatcttag
     1921 ctggtctggt ttccgtccgg acatgattaa ccgtctgcat ccagcgccac acgcggccag
     1981 tgcatgagcc agctcgtcta cttctccagc agctccgaaa acacgcagcg ttttatcgaa
     2041 cgtttaggtc tgcccgcggt gcgcatcccg ctcaatgagc gggaacggat tcaggtagac
     2101 gagccttaca tcctgatcgt gccctcttac ggcggcggcg gtacggctgg cgcggtgcca
     2161 cgacaggtaa ttcgcttttt aaacgacgag cacaaccggg cgttgcttcg cggcgttatt
     2221 gcttctggta atcgcaactt tggtgaggcg tatggccgcg ccggagatgt gattgcccgg
     2281 aaatgcggcg tgccgtggct gtaccgtttt gaactcatgg gtacgcaaag cgatatcgaa
     2341 aacgttcgta aaggagtaac cgaattttgg caacgacaac cgcagaatgc ctgacgcagg
     2401 aaacgatgga ttaccacgcg ctgaatgcga tgcttaacct ctacgatagc gcaggtcgca
     2461 ttcagttcga taaagaccgc caggccgttg acgcctttat tgcgacgcat gtgcgtccga
     2521 acagtgtgac cttcagtagc cagcagcagc gcctgaactg gctggtcaac gaaggttact
     2581 atgatgaaag cgttcttaat cgctactctc gcgactttgt cattacgctg tttgcccacg
     2641 cacacaccag cggttttcgt ttccagacat tcctcggggc atggaagttt tacaccagct
     2701 atacgttgaa gacattcgac ggtaaacgtt atctggaaga ttttgccgat cgagtaacga
     2761 tggtggcgct gacgctggca caaggcgatg agacgctggc gttgcaactg accgatgaaa
     2821 tgctgtcagg acgctttcag ccagccacgc caacattcct caactgcggt aagcagcagc
     2881 gcggcgaact ggtttcctgt tttttgctgc gtattgaaga caatatggag tcgattggtc
     2941 gggcggtaaa ttccgcactg cagctgtcga aacgcggcgg cggcgtagca tttttgctgt
     3001 cgaatctgcg agaagcgggc gcgccaatta aacgtattga aaatcaatct tctggcgtaa
     3061 ttccggtgat gaaaatgctg gaagacgcat tttcctatgc caaccaactc ggcgctcgtc
     3121 agggggctgg tgcagtctat ttacatgctc atcatcccga tattctgcgt tttctcgaca
     3181 cgaaacggga aaatgccgac gaaaaaatcc gcattaaaac actgtcgctt ggcgtggtga
     3241 tcccggatat cactttccat ctggcaaaag agaatgcgca gatggcgctg ttttcgcctt
     3301 atgacgtaga gcgagtttat ggcaagccgt ttgccgatgt ggccatcagc caacactatg
     3361 acgaactggt tgccgatgaa cgcattcgca aaaaatacct caacgcccgt gatttcttcc
     3421 agcgactggc agaaatccag tttgagtccg gctatcccta catcatgtat gaagacacgg
     3481 taaaccgtgc taaccctatc gccgggcgca taaatatgag taatctctgc tcagaaattt
     3541 tgcaggttaa cagcgcctca gagtatgacg agaatctcga ctatacccgc acaggccatg
     3601 atatttcctg caatttaggt tcgttgaata ttgcgcacac catggattcc cccgattttg
     3661 cccgcacggt agagactgcc gtgcgcggtt taacggcagt atcagatatg agtcatatcc
     3721 gcagcgtgcc gtccatcgaa gccggaaatg ccgcctcgca cgccatcgga ctggggcaga
     3781 tgaatttaca cggctatctg gcgcgagaag gcatcgctta tggttcgccg gaagcactgg
     3841 atttcaccaa tctctatttc tatgccatca cctggcatgc actgcgtacc tcgatgttgc
     3901 tggcacgcga acgcggtgaa accttcgccg ggttcaaaca gtcacgctat gccagtggtg
     3961 aatattttag ccaatatctg caagggaact ggcagccgaa aacggcgaaa gttggcgaac
     4021 tgtttacccg tagcggtatt acgttaccta cccgtgagat gtgggcgcag ctgcgcgacg
     4081 acgtgatgcg ctacggcata tacaaccaga atcttcaggc ggtgccgcca accggttcta
     4141 tctcttatat caaccatgct acgtcgagta ttcatccgat tgtggcgaaa gtagagatac
     4201 gcaaagaggg caaaacagga cgcgtttact accctgcccc gtttatgact aacgagaatc
     4261 tggcgctgta tcaggacgct tacgaaattg gcgcagaaaa gatcatcgac acctacgcgg
     4321 aagcgactcg ccatgtcgat caggggctgt cgctgacgct ttttttcccc gataccgcca
     4381 ccactcgcga tatcaacaaa gcgcagattt acgcctggcg caagggtatc aaaacgctct
     4441 attacatccg cctgcgtcag atggcgctgg aaggcactga aattgaaggc tgcgtctcct
     4501 gtgcacttta aggaatatct atgaaactct cacgtatcag cgccatcaac tggaacaaga
     4561 tatctgacga taaagatctg gaggtgtgga atcgcctgac cagcaatttc tggctaccag
     4621 aaaaggtgcc gctgtcgaac gatattcctg cctggcagac attaactgtc gtagaacaac
     4681 aactgacgat gcgcgttttt actggcctga cgctgctcga cacgctgcaa aatgttatcg
     4741 gcgcgccttc tctgatgccc gatgcactca cgcctcatga agaagcggta ttatcgaata
     4801 tcagctttat ggaagcggtt catgcccgct cttacagttc gattttctcg acgctatgcc
     4861 agaccaaaga tgtcgatgcc gcctacgcct ggagtgaaga aaacgcaccg ttgcagcgaa
     4921 aagctcagat tattcagcaa cattatcgcg gtgatgatcc gctgaaaaag aaaatcgcca
     4981 gtgtgtttct tgaatctttt ttgttctatt ccggtttctg gctgccgatg tatttttcca
     5041 gccgcggaaa gctgaccaat accgcggacc tgatccgtct gattatccgc gatgaagcag
     5101 tccacggtta ctacataggc tataaatatc agaaaaacat ggaaaagata tctctgggac
     5161 aacgtgaaga gttgaagagt ttcgccttcg atttgttgct ggaactctac gacaacgagt
     5221 tgcaatacac cgatgagctg tacgccgaaa ccccgtgggc tgacgatgtg aaagcgtttc
     5281 tctgttacaa cgccaataag gctttgatga atctgggcta cgaaccgtta tttcccgcag
     5341 aaatggcgga agtgaatccg gcaatcctcg ccgcgctttc gccgaatgcc gatgaaaatc
     5401 acgatttctt ttccggttca ggctcctctt atgtgatggg gaaagcggtt gaaacagaag
     5461 atgaagactg gaatttctga gggtgttatt ttcaaaaata tcactacccg cagcagggaa
     5521 ataattcccg ccaaatagct ttttatcacg caaataattt gtggtgatct acactgatac
     5581 tctgttgcat tattcgcctg aaaccacaat attcaggcgt tttttcgcta tctttgacaa
     5641 aaaatatcaa ctttctcgat ttgctctcag cccttatatc acgggaaatt ccggcgattt
     5701 gctcgcatca atattcatgc cacatttgcc atcaggggtt gcctcagatt ctcagtatgt
     5761 tagggtagaa aaaagtgact atttccattg ggtaatatat cgacatagac aaataaagga
     5821 atctttctat tgcatggcaa ttaaattaga aattaaaaat ctttataaaa tatttggcga
     5881 gcatccacag cgagcgttca aatatatcga acaaggactt tcaaaagaac aaattctgga
     5941 aaaaactggg ctatcgcttg gcgtaaaaga cgccagtctg gccattgaag aaggcgagat
     6001 atttgtcatc atgggattat ccggctcggg taaatccaca atggtacgcc ttctcaatcg
     6061 cctgattgaa cccacccgcg ggcaagtgct gattgatggt gtggatattg ccaaaatatc
     6121 cgacgccgaa ctccgtgagg tgcgcagaaa aaagattgcg atggtcttcc agtcctttgc
     6181 cttaatgccg catatgaccg tgctggacaa tactgcgttc ggtatggaat tggccggaat
     6241 taatgccgaa gaacgccggg aaaaagccct tgatgcactg cgtcaggtcg ggctggaaaa
     6301 ttatgcccac agctacccgg atgaactctc tggcgggatg cgtcaacgtg tgggattagc
     6361 ccgcgcgtta gcgattaatc cggatatatt attaatggac gaagccttct cggcgctcga
     6421 tccattaatt cgcaccgaga tgcaggatga gctggtaaaa ttacaggcga aacatcagcg
     6481 caccattgtc tttatttccc acgatcttga tgaagccatg cgtattggcg accgaattgc
     6541 cattatgcaa aatggtgaag tggtacaggt cggcacaccg gatgaaattc tcaataatcc
     6601 ggcgaatgat tatgtccgta ccttcttccg tggcgttgat attagtcagg tattcagtgc
     6661 gaaagatatt gcccgccgga caccgaatgg cttaattcgt aaaacccctg gcttcggccc
     6721 acgttcggca ctgaaattat tgcaggatga agatcgcgaa tatggctacg ttatcgaacg
     6781 cggtaataag tttgtcggcg cagtctccat cgattcgctt aaaaccgcgt taacgcagca
     6841 gcaaggtctt gatgcggcgc tgattgatgc gccgttagca gtcgatgcac aaacgcctct
     6901 tagcgagttg ctctctcatg tcggacaggc accctgtgcg gtgcccgtgg tcgacgagga
     6961 ccaacagtat gtcggcatca tttcgaaagg aatgctgctg cgcgctttag atcgtgaggg
     7021 ggtaaataat ggctgatcaa aataatccgt gggataccac gccagcggcg gacagtgccg
     7081 cgcaatccgc agacgcctgg ggtacaccga cgactgcacc gactgacggc ggtggtgctg
     7141 actggctgac cagtacgcct gcgccaaacg tcgagcattt taatattctc gatccgttcc
     7201 ataaaacgct gatcccgctc gacagttggg tcactgaagg gatcgactgg gtcgttaccc
     7261 atttccgtcc cgtcttccag ggcgtgcgcg ttccggttga ttatatcctc aacggtttcc
     7321 agcaattgct gctgggtatg cccgcaccgg tggcgattat cgttttcgct ctcatcgcct
     7381 ggcagatttc cggggtcgga atgggtgtgg cgacgctggt ttcgctgatt gccatcggcg
     7441 caatcggtgc ctggtcgcag gcaatggtga ctctggcgct ggtgttaacc gccctgctgt
     7501 tctgtatcgt catcggtttg ccgttgggga tatggctggc gagaagtccg cgagcggcga
     7561 aaattattcg tccactgctt gatgccatgc agaccacgcc agcgtttgtt tatctggtgc
     7621 caatcgtcat gctatttggt atcggtaacg tgccgggcgt ggtggtgacg atcatctttg
     7681 ctctgccgcc gattatccgt ctgaccattc tggggattaa ccaggttccg gcggatctga
     7741 ttgaagcctc gcgctcattc ggtgccagcc cgcgccagat gctgttcaaa gttcagttac
     7801 cgctggcgat gccgaccatt atggcgggcg ttaaccagac gctgatgctg gccctttcta
     7861 tggtggtcat cgcctcgatg attgccgtcg gcgggttggg tcagatggta cttcgcggta
     7921 tcggtcgtct ggatatgggg cttgccaccg ttggcggcgt cgggattgtg atcctcgcca
     7981 ttatcctcga tcgtctgacg caggccgttg ggcgcgactc acgcagtcgc ggcaaccgtc
     8041 gctggtacac cactggccct gttggtctgc tgacccgccc attcattaag taactctgca
     8101 cttgcccggt gacgccgggc attatcaccc tgccaaaaaa aggaataaca atgcgacata
     8161 gcgtactttt tgcgacagcg tttgccacgc ttatctctac acaaactttt gctgccgatc
     8221 tgccgggcaa aggcattact gttaatccag ttcagagcac catcactgaa gaaaccttcc
     8281 agacgctgct ggtcagtcgt gcgctggaga aattaggtta taccgtcaac aaacccagcg
     8341 aagtagatta caacgttggc tacacctcgc ttgcttccgg cgatgcaacc ttcaccgccg
     8401 tgaactggac gccactgcat gacaacatgt acgaagctgc cggtggcgat aagaaatttt
     8461 atcgtgaagg ggtatttgtt aacggcgcgg cacagggtta cctgatcgat aagaaaaccg
     8521 ccgaccagta caaaatcacc aacatcgcac aactgaaaga tccgaagatc gccaaactgt
     8581 tcgataccaa cggcgacgga aaagcggatt taaccggttg taaccctggc tggggctgcg
     8641 aaggtgcgat caaccaccag cttgccgcgt atgaactgac caacaccgtg acgcataatc
     8701 aggggaacta cgcagcgatg atggccgaca ccatcagtcg ctacaaagag ggcaaaccgg
     8761 tgttttatta cacctggacg ccgtactggg tgagtaacga actgaagccg ggcaaagatg
     8821 tcgtctggtt gcaggtgccg ttctccgcac tgccgggcga taaaaacgcc gataccaaac
     8881 tgccgaatgg tgcgaattat ggcttcccgg tcagcaccat gcatatcgtt gccaacaaag
     8941 cctgggccga gaaaaacccg gcagcagcga aactgtttgc cattatgcag ttgccagtgg
     9001 cagatattaa cgcccagaac gccattatgc atgacggcaa agcctcagaa ggcgatattc
     9061 agggacacgt tgatggttgg atcaaagccc accagcagca gttcgatggc tgggtgaatg
     9121 aggcgctggc agcgcagaag taatttttat tcgggcggat aaggcgtttt tgccgcatcc
     9181 gccgttctgt gcacaatgcc tgatgcgacg ctggcgcgtc ttatcatgcc tacaaaccac
     9241 atcgcacatt tcaacaatct atctttcatc ccatattcat caacatccgc tattattgat
     9301 ttccagctta atcatcacct gatgaacaaa aataatgact aaacctaatc atgagcttag
     9361 cccggcgctg atcgtgctga tgtctatcgc caccggtctg gcggtagcca gtaactatta
     9421 cgcccagcca ttgctcgaca ccatcgcgcg taacttttcc ctttccgcca gttcggcagg
     9481 ctttattgtt accgccgcgc agttgggcta tgccgcaggt ctactgtttc ttgttcccct
     9541 cggtgatatg tttgaacgcc gccgcctgat tgtctcgatg accttactgg cggcatgcgg
     9601 catgttgatt accgccagca gtcagtcgct ggcgatgatg atcctcggta cggcattaac
     9661 cggtttattc tcagtcgtgg cacaaattct ggttccgctg gcagcgacgc tggcttcacc
     9721 ggataaacgc ggcaaagtgg ttggcactat tatgagcggt ctgctgttgg ggatcttgct
     9781 ggcacggaca gttgccggat tgctggcgaa tctcggcggc tggcgcaccg tcttttgggt
     9841 tgcttcggtg ttaatggcac tgatggcgct ggcattatgg cgtggtctgc cacaaatgaa
     9901 atcagaaacc cacctcaact acccacagtt gttgggttcc gttttcagta tgtttatcag
     9961 cgataaaatt ctgcgtaccc gcgcgttgct gggctgcctg acctttgcca atttcagcat
    10021 tctctggacc tcaatggcct ttttgcttgc cgctccacct tttaactaca gcgatggtgt
    10081 cattggtctg tttggacttg cgggagctgc cggagcgttg ggcgctcgtc cggcgggcgg
    10141 ttttgccgat aagggcaaat cgcaccacac cacaactttc ggtctgctgc tgctattact
    10201 ttcatggctg gcgatctggt ttggtcacac ttccgtactg gcgttgatta tcggaatcct
    10261 ggtgctggat ctcaccgtgc agggcgtgca tatcactaac cagacggtaa tttatcggat
    10321 acatcctgat gcgcgcaatc gcctgaccgc aggttacatg actagctact ttattggcgg
    10381 tgccgccggt tcgctaattt cagcctcagc ctggcaacat ggcggttggg ctggcgtttg
    10441 tctggctggc gcgacgattg ccctggttaa cttactggtc tggtggcgag gttttcatcg
    10501 tcaggaagcc gcaaattaag caatcagcaa ccgttttcgt ggctttacac ttataagggt
    10561 gttaagaagc ccatcagtct gataaggtta agatattcat tcagtctatt tataatatta
    10621 acaatcgtta agcgtacact ctatggaaag ccctactcca cagcctgctc ctggttcggc
    10681 gaccttcatg gaaggatgca aagacagttt accgattgtt attagttata ttccggtggc
    10741 ctttgcgttc ggtctgaatg cgacccgtct gggattctct cctctcgaaa gcgttttttt
    10801 ctcctgcatc atttatgcag gcgcgagcca gttcgtcatt accgcgatgc tggcagccgg
    10861 gagtagtttg tggattgctg cactgaccgt catggcaatg gatgttcgcc atgtgttgta
    10921 tggcccgtca ctgcgtagcc gtattattca gcgtctgcaa aaatcgaaaa ccgccctgtg
    10981 ggcgtttggc ctgacggatg aggtttttgc cgccgcaacc gcaaaactgg tacgcaataa
    11041 tcgccgctgg agcgagaact ggatgatcgg cattgccttc agttcatggt catcgtgggt
    11101 atttggtacg gtaatagggg cattctccgg cagcggcttg ctgcaaggtt atcccgccgt
    11161 tgaagctgca ttaggtttta tgcttccggc actctttatg agtttcctgc tcgcctcttt
    11221 ccagcgcaaa caatctcttt gcgttaccgc agcgttagtt ggtgcccttg caggcgtaac
    11281 gctattttct attcccgtcg ccattctggc aggcattgtc tgtggctgcc tcactgcgtt
    11341 aatccaggca ttctggcaag gagcgcccga tgagctatga ggttctgctg cttgggttac
    11401 tagttggcgt ggcgaattat tgcttccgct atttgccgct gcgcctgcgt gtgggtaatg
    11461 cccgcccaac caaacgtggc gcggtaggta ttttgctcga caccattggc atcgcctcga
    11521 tatgcgctct gctggttgtc tctaccgcac cagaagtgat gcacgataca cgccgtttcg
    11581 tgcccacgct ggtcggcttc gcggtactgg gtgccagttt ctataaaaca cgcagcatta
    11641 tcatcccaac actgcttagt gcgctggcct atgggctcgc ctggaaagtg atggcgatta
    11701 tataacccac aagaatcatt tttctaaaac aatacattta ctttatttgt cactgtcgtt
    11761 actatatcgg ctgaaattaa tgaggtcata cccaaatgga tagttcgttt acgcccattg
    11821 aacaaatgct aaaatttcgc gccagccgcc acgaagattt tccttatcag gagatccttc
    11881 tgactcgtct ttgcatgcac atgcaaagca agctgctgga gaaccgcaat aaaatgctga
    11941 aggctcaggg gattaacgag acgttgttta tggcgttgat tacgctggag tctcaggaaa
    12001 accacagtat tcagccttct gaattaagtt gtgctcttgg atcatcccgt accaacgcga
    12061 cgcgtattgc cgatgaactg gaaaaacgcg gttggatcga acgtcgtgaa agcgataacg
    12121 atcgccgctg cctgcatctg caattaacgg aaaaaggtca cgagtttttg cgcgaggttt
    12181 taccaccgca gcataactgc ctgcatcaac tctggtccgc gctcagcaca acagaaaaag
    12241 atcagctcga gcaaatcacc cgcaaattgc tctcccgtct cgaccagatg gaacaagacg
    12301 gtgtggttct cgaagcgatg agctaacgcg tcatctcgct caaaaatcca gatttataaa
    12361 agaaaaaatg actggccagc atcgcaacat gctggccttt ttggcaagca ggtcggctca
    12421 gccgatgagt taagaagatc gtggagaaca atatgagcgc aaatgcggag actcaaaccc
    12481 cgcagcaacc ggtaaagaag agcggcaaac gtaagcgtct gctcctcctt ctcaccttgc
    12541 tctttataat tattgccgta gcgataggga tttattggtt tttggtactg cgtcacttcg
    12601 aagaaaccga tgacgcatac gtggcaggga atcaaattca aattatgtct caggtgtctg
    12661 gcagcgtgac gaaagtctgg gccgataaca ccgattttgt aaaagaaggc gacgtgctgg
    12721 tcactctcga cccgacagat gctcgccagg cgtttgaaaa agccaaaact gcactggctt
    12781 ccagcgttcg ccaaacccac cagctgatga ttaacagcaa gcagttgcag gcgaatattg
    12841 aggtgcagaa aatcgccctc gcgaaagcac aaagcgacta caaccgccgt gtgccgctgg
    12901 gcaatgccaa cctgattggt cgcgaagagc tgcaacacgc ccgcgacgcc gtcaccagtg
    12961 cccaggcgca actggacgtc gcgattcaac aatacaatgc caatcaggcg atgattctgg
    13021 ggactaaact ggaagatcag ccagccgtgc aacaggctgc caccgaagta cgtaacgcct
    13081 ggctggcgct ggagcgtact cgtattatca gtccgatgac cggttatgtc tcccgccgcg
    13141 cggtacagcc tggggcgcaa attagcccaa cgacgccgct gatggcggtc gttccagcca
    13201 ccaatatgtg ggtggatgcc aactttaaag agacgcagat tgccaatatg cgtatcggtc
    13261 agccggtcac tatcaccacg gatatttacg gcgatgatgt gaaatacacc ggtaaagtgg
    13321 ttggtctgga tatgggcaca ggtagcgcgt tctcactgct tccagcgcaa aatgcgaccg
    13381 gtaactggat caaagtcgtt cagcgtctgc ctgtgcgtat cgaactggac cagaaacagc
    13441 tggagcaata tccgctgcgt atcggtttgt ccacgctggt gagcgtcaat accactaacc
    13501 gtgacggtca ggtactggca aataaagtac gttccactcc ggtagcggta agcaccgcgc
    13561 gtgaaatcag cctggcacct gtcaataaac tgatcgacga tatcgtaaaa gctaacgctg
    13621 gctaatccag aggtgcgtgt gatgcaacag caaaaaccgc tggaaggcgc gcaactggtc
    13681 attatgacga ttgcgctgtc actggcgaca ttcatgcagg tgctggactc caccattgct
    13741 aacgtggcga tccccactat cgccgggaat ctgggctcat cgctcagcca gggaacgtgg
    13801 gtaatcactt ctttcggggt ggcgaatgcc atctcgatcc cgcttaccgg ctggctggca
    13861 aagcgcgtcg gggaagtgaa actgttcctt tggtccacca tcgcctttgc tattgcgtcg
    13921 tgggcgtgtg gtgtctccag cagcctgaat atgctgatct tcttccgcgt gattcagggg
    13981 attgtcgccg ggccgttgat cccgctttcg caaagtctat tgctgaataa ctacccgcca
    14041 gccaaacgct cgatcgcgct ggcgttgtgg tcgatgacgg tgattgtcgc gccaatttgc
    14101 ggcccgatcc tcggcggtta tatcagcgat aattaccact ggggctggat attcttcatc
    14161 aacgtgccga ttggcgtggc ggtggtgttg atgacactgc aaactctgcg cggacgtgaa
    14221 acccgcaccg aacggcggcg gattgatgcc gtggggctgg cactgctggt tattggtatc
    14281 ggcagcctgc agattatgct cgaccgcggt aaagagctgg actggttttc atcacaggaa
    14341 attatcatcc ttaccgtggt ggcggtggtg gctatctgct tcctgattgt ctgggagctg
    14401 accgacgata acccgatagt cgatctgtcg ttgtttaagt cgcgcaactt caccatcggc
    14461 tgcttgtgta tcagcctcgc gtatatgctc tacttcggcg ctattgttct gctgccgcag
    14521 ttgttgcagg aggtctacgg ttacacggcg acctgggcag gtttggcctc tgcgccggta
    14581 gggattattc cggtgatcct gtcgccgatt atcggccgct tcgcgcataa actggatatg
    14641 cggcggctgg taaccttcag ctttattatg tatgccgtct gcttctactg gcgtgcctat
    14701 acctttgaac caggtatgga ttttggcgcg tcggcctggc cgcagtttat ccaggggttt
    14761 gcggtggcct gcttctttat gccgctgacc accattacgc tgtctggttt gccaccggaa
    14821 cgactggcgg cggcatcgag cctctctaac tttacgcgaa cgctggcggg gtctatcggc
    14881 acgtcgataa ccacgaccat gtggaccaac cgcgagtcga tgcaccatgc gcagttgact
    14941 gagtcggtaa acccgttcaa cccgaatgcc caggcgatgt acagtcaact ggaagggctt
    15001 gggatgacgc aacagcaggc atcaggctgg attgcccagc agatcaccaa tcaggggctg
    15061 attatttccg ccaatgagat cttctggatg tcagccggga tattcctcgt cctgctgggg
    15121 ctggtgtggt ttgctaaacc gccatttggc gcaggtggcg gcggaggcgg tgcgcactaa
    15181 gtacaactaa gccagttcat ttgaactggc ttttttcaat taattgtgaa gatagtttac
    15241 tgactagatg tgcagttcct gcaacttctc tttcggcagt gccagttctt cgttgctgtt
    15301 gatgcgtacg tcacgttcca gaatgctacg cgcaatatcc tgcgcttcct gcaacgagtg
    15361 catctggtaa gtgccacact ggtagacgtt cagttccggg atctgattct gatcctgcac
    15421 tttcagcacg tcttccattg ccgctttcca ggcatcagca acacgctgct catctggcgt
    15481 accaatcaga ctcatataaa aaccggtgcg gcagcccatt ggcgagatat cgataatctc
    15541 tacaccatta ccgttaagat ggttacgcat aaaaccagca aacaggtgct ccagggtatg
    15601 gatccctctt tctggcatca cttctttgtt cggcacgcag aagcgcagat cgaacacggt
    15661 gattgcgtcg ccatgcgggg tgttcattgt tttcgccacc cgaactgcag gcgcttccat
    15721 ccgggtatga tcgactgtga agctatctaa caacggcatt tagccacctc cggtaatttt
    15781 tttaaaaatt ttctgaactc tttcttccca ggcgagtctg agtatatgaa agacgcgcat
    15841 ttgttatcat catccctgaa ttcagagatg aaattttggc cactcacgag tggccttttt
    15901 cttttctgtc aggcgtgttt ttccagccac accgcaaacg gttcggtatc agcggcttcc
    15961 atttcctgct gacggcgttc agacgcctcg cgctcggcta caaaatcctc ttcgcgcaga
    16021 atttccagcg gctcttcacg cagcagatta cggtaggctt ctgcaaatgc tttgcctgtt
    16081 ccgccaatac cagtatcaat catagacctt aagatacggg cagagaaagt cagatcggga
    16141 ttatcgaagc aggcaaccag ttcatcacac actttctgat acgcttcgcc gccgttaata
    16201 ctatccagcg tttgcgcgac gcgtttcaga tcgcggaaca gatctttacc cacctgcggt
    16261 aacgggaact gtgcggtttc gcagccgata cccagcgtca gacccggttt gcgaccttcg
    16321 aggatcaccc ggttccagtt aacgcgtgta caggcaagtt cgctactgct catttccggt
    16381 gcatcagcca gcgcacacca gaccataaac aggtcgagga atcgcacctg ctgttcatct
    16441 acaccaatcg gcgagaacgg gttgatgtcc agcgaacgca cttcaatata ttcaatgccg
    16501 ccacgtaaca gcgcatcaga aggcgactcg ccgctgcggg taacgcgttt tggacgaatc
    16561 ggcgcgtaca gttcgttttc aatctgcaac acgttgctgt tgatttgcag cctcttaccg
    16621 tctttctcaa taccaatctt cgcgtactct tccgatggcg ttttgattgc ctgtttaagg
    16681 cccgctacgt actcgtaaag atcgttgaag gtaataccaa gattgctttg cgatttattg
    16741 gtatagccga gatcgctcaa acgaagagag gtcgcatacg gcaggtaata cataccgcac
    16801 tcggttttct caaacggcag cgacgttggt tttccttgca ggaaagaaga acaaatcgcc
    16861 ggagatgcac caaacagata aggaatgacc caaccgaaac gatagtaatt gcggataacg
    16921 cggaaatagc ccgcagaaat tttctctttg gcatcagcgc ccgagatatc accgcacttc
    16981 gcttgccaga atgccattgg caaagagaaa ttgtagtgca cgccggaaat ggtttgcatc
    17041 agcgcgccgt agcgattttt cagcccttca cgatacagcg ttttaaagcg tccggtgtta
    17101 gaagtgccgt actgtgccag ttcgatgtcc tgaccttctg cgatgtagca tggcatactt
    17161 aacggccaca tccgctcatc gcccatattg cgcgccgtat aacgatgcag atcgcgcata
    17221 aaggtcagca tatgttcaat atcaccatcc actggtgtaa tgaattccag caatgcttcc
    17281 gcaaaatcgg tagtaatcca tttgtgcgtc agtgcggaac ctaatgcttc aggatgacct
    17341 gttgttgcca gtgtgccatc agcattaaca cgcaaagttt cgcgctccag cccacgctgt
    17401 atccccttta acgcctgagg atgtttttcc agccaggcca gcgcctgtga tacgtccggg
    17461 atcaaattga cctcccgcct gtcaaaatcg ttttaattag cataactgta atggtgacca
    17521 tatgtgcagg cctacaatta gtgccaccac atcatgccct gaacggtcgc tgctgcaact
    17581 gcaacatagc gtaacgcttt accaaggcac aaaaaaaaga ttaccggtcc ccacgagatg
    17641 cgcatccatc ccgctaacag acacagtaaa tcgccaacca cgggcatcca gcttaataat
    17701 agcgtgactg caccatagcg tttcagccag ccggtagctt tctcttgcca gcgcgatgtt
    17761 ttacgcaatg gaaagaaacg cccaaggata acgttagtta accctccaag gctattaccc
    17821 attgttgctg ttaaaactaa aacccaggga tgactgatcc cggaaagcaa cattgccacc
    17881 agcacgactt cggagttgcc gggtaatagt gtagcgctga gaaaactact ggcaaacaac
    17941 gagaaaagcg ataacgcttc actcacagca agcgaacatc cacggcgtcc atgcctgctg
    18001 cacgggccgc ctgaataccg aaatcggcat cttcaaagac cacacactgc gtcggttgca
    18061 cgcccatacg ctgcgcgcac aacaaaaatg tgtctggcgc gggtttatgg tgtttgacgt
    18121 gatcggcagc gacgacggcg tcaaaataat ggcgtaatcc caggtgcgcc agcaatgcct
    18181 cagcgatggc gctttcactc cccgttccta cagccattgg gcgacgacca tgccaacttt
    18241 tcaccacatc aacaagagga agcggttcga cgctatccag cagcatactt cttactgctt
    18301 ctgttttttc acgcgctaac gcatgcgggt cgagatcggc ctgattcagc tcaataattg
    18361 cctgagcaat acgccaggtg ggcgatccat taagcgcaat catcgcctga atatcgtact
    18421 gaagaccgta gtgccctaat acttcgcgcc acgctttacg gtgcgtaggc tccgtatcca
    18481 ggattgtgcc atccatatca aaaattaaac ctgcataacg ctcgtacatg gtcttctcgc
    18541 aagtcgaaaa atatgacgct actttagcgt aattgcttga ttttgtcgct gatggcgaag
    18601 gagaagaaaa ttcaggaaat ggataaagga gttatttaga aatgagatat ttttgaagga
    18661 aattttttgg agaagatggt gcatccggga ggatgactca ctgacgttcg cccttcgggc
    18721 cgttgctggc gcaacgttat ccttcctggt gcctgcggtt aataccgcta tctcttcgat
    18781 accttcattg ctgaaggtta cggagaatat ggtgcatccg ggaggattcg aacctccgac
    18841 cgctcggttc gtagccgagt actctatcca gctgagctac ggatgcatcg ggaaaactta
    18901 ttctactgct gatattgata ccgctactaa agccatatca attaagagat ggtgcatccg
    18961 ggaggattac tcgccttgcg gctcgccctt cgggccgttg ctaaagcaac gttatcatcc
    19021 ctagtgcctg cggttaattc cgctacctct tcgatacctt cattgctgaa gatttcggag
    19081 aatatggtgc atccgggagg attcgaacct ccgaccgctc ggttcgtagc cgagtactct
    19141 atccagctga gctacggatg catcgggaaa tttattttac tgctgatatt gataccgcta
    19201 ctaaagccat atcaagtaag agatggtgca tccgggagga ttcgaacctc cgaccgctcg
    19261 gttcgtagcc gagtactcta tccagctgag ctacggatgc atcgggaaac ttactttact
    19321 gcagattttt tgataccgct actaaagccg tatcaagtaa gagatggtgc atccgggagg
    19381 attactcgcc ttgcggctcg cccttcgggc cgttgctaaa gcaacgttat cctccctggt
    19441 gcctgcggtt attaccgcca cctcttccat accttcatcg ctgaaagtac gtagaatatg
    19501 gtgcatccgg gaggattcga acctccgacc gctcggttcg tagccgagta ctctatccag
    19561 ctgagctacg gatgcaaatg gcggtgaggc ggggattcga accccggatg cagcttttga
    19621 ccgcatactc ccttagcagg ggagcgcctt cagcctctcg gccacctcac cacacgcctc
    19681 ttacgagtgc ttcgaagaac ttgtttatcg ctcatcgtcg ctgcgtggcg cacatattac
    19741 tttctgagac ttataagtca aacaattttt cctacacttt tatcgtttgc acacttcacg
    19801 ttcaattagt ctgtaaaaac gtcaaaaaga gtgttttatc aacagaagaa tggaggtctg
    19861 acagatagta gtaatgcaaa aaaatggaga cttaagttga atgaacggga gtaaagcgaa
    19921 aagactatag agtgaaggag aaattttgag ggtgcgtctc accgataaag atgagacgcg
    19981 gaaagattag taactggact gctgggattt ttcagcctgg atacgctggt agatctcttc
    20041 acggtgaaca gaaacttcct tcggggcatt tacgccaata cgtacctggt tgccctttac
    20101 ccctaaaact gtcacggtga cctcatcccc aatcatgagg gtctcaccaa ctcgacgagt
    20161 cagaatcagc attctttgct ccttgaaaga ttaaaagagt cgggtctctc tgtatcccgg
    20221 cattatccat catataacgc caaaaagtaa gcaatgacaa acacattaca tctaagcagt
    20281 catggcatta cattctgtta aacctaagtt tagccgatat acacaacttc aacctgactt
    20341 tatcgttgtc gatagcgtta atgcgaatgc cgtgaagcga gtccacggca ttgcctgacg
    20401 cttatattat tgcaatttcg cgctgaccca gcctttcaca ctggctaacg ctgcaggtaa
    20461 ggccgcagca tccgtaccac cggcttgcgc catgtcagga cgtccaccac ccttgccgcc
    20521 cacctgctga gcgaccatac caatcagttc ccctgctttc acacgatctg tgacgtcctt
    20581 agatacgcct gcaatcagag aaaccttacc ttcgactacc gttgccagca cgataattgt
    20641 cgaccccagc tgatttttta aatcgtcaac catggtacgc aacattttcg gctcaacacc
    20701 gctaagctcg ctaaccaaca gcttaacacc attaacatca attgccttac tggaaagatt
    20761 tgcgctctcc tgtgcggcag cttgttcttt aagctgttgt aactcttttt ccaactgacg
    20821 cgtacgttcc agtactgagc gcactttatc agccagatta ttgctatcgc ctttcagcaa
    20881 atgcgcgact tcgcttaagc gatcgctgtc tgcatgaacg gtggcgatag caccttctcc
    20941 ggttaccgct tcgatacgac gaacgcctgc agcagtaccc gattcagaga tgatgcggaa
    21001 cagaccaata tcaccagtgc ggctggcgtg agtaccgcca cacaactcgg tagagaaatc
    21061 gcccatgctc agcacgcgta cgcgctcatc atacttctcg ccgaacagcg ccatcgcacc
    21121 tttcgctttc gccgcttcga gatccatgat gttggtttcg atcggcaaat tgcgacgaat
    21181 ctgtgtgttc accaggtctt cgaccgcacg aatctcttct ggtttcatcg cttcgttgtg
    21241 tgagaagtcg aagcgcagca ccttgtcgtt aaccagtgaa cctttctgcg atacatgagt
    21301 acccagaacc tggcgcagcg cagcgtgcat caggtgcgtt gcggagtgat tcagacgaat
    21361 acgggcgcga cgagcctcat caacatcagc ctgcaccgcg tcgcccactt tcagagaacc
    21421 cgcagcaagt ttaccgatgt gaccaatcgc ctggccgtat ttctgcgtat cttccaccgc
    21481 aaaggagaag ttagcgcctt tcagttcgcc tttatcgcca acctgaccgc cggattccgc
    21541 atagaatggc gtttgatcca gcacgaccac agcttcctgg cctgcattga tggcatcaac
    21601 cgctttacca tcaacaaaca gcgcagtcac tttgccgttc agttccagat ggtcatagcc
    21661 tttaaattca gatgcactgt caacacggat cattgcgttg taatcggcac caaagccgct
    21721 ggcttcgcgc gcgcgacgac gctgctcttc cattgcagct tcaaaaccag cttcgtcaac
    21781 tttgatgttg cgctcacgac aaacatcagc cgtcaggtca accgggaagc cataggtgtc
    21841 gtacagacgg aaagcagttt caccatccag cgtatcacca gaaagttttg ccagctcttc
    21901 atccagcaac gccagaccgc gctccagagt acgagcaaac tgctcttctt cagtcttcag
    21961 cacctgctca acctgcgcct gctggcgttt caggtcttca cccgcagagc ccataacgtc
    22021 gatcagcgga ccaaccagtt tgtagaagaa ggtttctttc gcgccgagca tattaccgtg
    22081 acgcactgcg cgacgaatga tacgacgcag tacataacca cggttttcat tggacggcat
    22141 tacgccatcc gcgatcagga acgcacaaga acgaatgtgg tcagcgatta cgcgcagcga
    22201 tttattgctc agatcggttg cgccagtgac tttcgctacc gcctggatca gcgtgcggaa
    22261 caggtcgatg tcatagttag agttaacgtg ttgcagcacc gcagcaatac gctccagacc
    22321 cataccggta tctacagacg gcttcggcag cggttccatc gtgccatcgg cctggcggtt
    22381 gaactgcatg aagacgatgt tccagatctc aatgtagcgg tcgccgtctt cttccgggct
    22441 tcccggaggg cccccccaaa tgtggtcgcc gtgatcgtag aagatttcgg tgcacgggcc
    22501 gcacggacca gtgtcaccca tctgccagaa gttgtcagat gcgtatggcg cacctttgtt
    22561 atcgccgatg cgaataatac gttcgcgcgg gatccctact tctttttccc agatttcgta
    22621 ggcttcgtcg tcgctttcat agacggtaac ccacagacgc tctttcggca gggcaaacca
    22681 tttttcgctg gtcagcagtt cccatgcaaa ctgaatggca tcgtgtttga aatagtcgcc
    22741 gaagctgaag ttgcccagca tttcgaagaa ggtatggtga cgcgcggtgt aaccgacgtt
    22801 ttccaggtcg ttgtgtttac cacccgcacg cacgcagcgt tgggaagtgg tagcgcggga
    22861 ataattacgc ttgtcgagcc caaggaacac atccttgaac tggttcatcc cggcgttggt
    22921 aaacaacaaa gttgggtcgt tatggggtac cagggagctg ctggcaacta cctgatgtcc
    22981 cttactatgg aaaaagtcga gaaacgcctg acggatctca gcggtgctct tgctcataat
    23041 tatcctgaaa tcaagctaac gaaatatcgc caccagctcc agcgtgtctt aaccgccggg
    23101 ctggtaactg aaaagtggga ataagataag ttttcttgac tgggaagtaa aataccgtat
    23161 gcgttcagtc ggcaaaattt cgccaaatct cctggatatc ttccatcaga tagccacgat
    23221 agagcagaaa acgctggatc ttaacttttt ctgaaaagac agttggcaaa ggttcgccat
    23281 attttcgcgt cgcctgatcg cgcgccagtg cgcaccagtc gatgtcacat tcacgcatcg
    23341 ctttttctgt cgcttcgcgg gaaatacctt tctgattcag ttcctggcga atacgcgcag
    23401 gtccataacc tttgcggcta cggctggcga taaagcgcgc aacaaatcgg ctgtcatcga
    23461 gatagccatg ttcatggcac caggcaataa cgcgctcgta atcttctgcc gtagcatcaa
    23521 tctcttctgg gccatttttg cccataatcg gtgccgcgag tttacgtcgc agttcttgct
    23581 cactgtgatc gcgcaccgcc agaatgcgta ccgcacgatc caacaggcga gcatatgccg
    23641 ggcgacggga tgttgattct gtcatggcat atccttacaa cttaaaaaag caaaagggcc
    23701 gcagatgcga cccttgtgta tcaaacaaga cgattaaaaa tcttcgttag tttctgctac
    23761 gccttcgcta tcatctacag agaaatccgg cgttgagttc gggttgctca gcagcaactc
    23821 acgtactttc ttctcgatct ctttcgcggt ttccgggtta tctttcagcc aggcagtcgc
    23881 attcgcttta ccctgaccga tcttctcacc tttgtagctg taccacgcgc ctgctttctc
    23941 gatcagcttc tcttttacgc ccaggtcaac cagttcgccg tagaagttga taccttcgcc
    24001 gtagaggatc tggaattcag cctgtttaaa cggcgcagcg attttgttct tcaccacttt
    24061 cacgcgggtt tcgctaccca ccacgttttc gccctctttc accgcgccga tacgacggat
    24121 gtcgagacga acagaggcgt agaatttcag cgcgttacca ccggtagtgg tttccgggtt
    24181 accgaacatc acaccaattt tcatacggat ctggttgatg aagatcagca gcgtgttgga
    24241 ctgcttcagg ttacccgcca gcttacgcat cgcctggctc atcatacgtg ccgcaaggcc
    24301 catgtgagag tcgccgattt cgccttcgat ttccgctttc ggcgtcagtg ccgccacgga
    24361 gtcaacgacg ataacgtcta ctgcgccaga acgcgccagg gcgtcacaga tttccagtgc
    24421 ctgctcgccg gtgtccggct gggagcacag caggttgtcg atatcgacgc ccagtttacg
    24481 tgcgtagatt gggtccagcg cgtgttcagc atcgataaac gcacaggttt taccttcacg
    24541 ctgcgctgcg gcgatcacct gcagcgtcag cgtggtttta ccggaagatt ccggtccgta
    24601 gatttcgacg atacggccca tcggcagacc acctgcccca agcgcgatat ccagtgaaag
    24661 cgaaccggta gagatggttt ccacatccat ggaacggtct tcacccaggc gcatgatgga
    24721 gcctttacca aattgtttct caatctggcc cagtgctgcc gccaacgctt tctgtttgtt
    24781 ttcgtcgata gccattttta ctcctgtcat gccgggtaat accggatagt caatatgttc
    24841 tgttgaagca attatactgt atgctcatac agtatcaagt gttttgtaga aattgttgcc
    24901 acaaggtctg caatgcatac gcagtagcct gacgacgcac cgcatcacgg tcgccgctga
    24961 agcattcccg ccgggtaatg ccttcaccgc gggcagtggc aaaagcaaac cagacggtgc
    25021 cgacaggctt ctcttcactg ccgccatccg gcccggcgat accactaata gacacggcat
    25081 aatcagcacg agccgctttc agtgcgccta tcgccatttc caccacgacg ggttcactca
    25141 ccgcgccatg ctgcgccagc gtctcttcgc gtacgccgat catctgcgct ttggcttcgt
    25201 tactgtaggt gacaaatccg cgttcaaacc aggcggagct accggcaata tcggtaatca
    25261 ctttcgctac ccaaccaccg gtacaagact cggcagttgt tacggttgcg ccacgggctt
    25321 tcagcgcctg cccaacctgt tcacttaact gcatcagttc actgtcagtc atcacaacct
    25381 ctgtcagtca aaaatttatg ccggacaaga tagcactttc gtcaggaaga tggtgttggc
    25441 gttgcaattt tacgaggagg attcagaaaa aagctgatta gccagaggga agctcacgcc
    25501 cccctcttgt aaatagctac tgtactcgcg tcagcgccac ggcttgtcct aactgccaga
    25561 ccgccattgc gtaatgggtg ctgtggttgt aacgggtgat ggtgtagaag ttcggcagac
    25621 cgtaccagta ctggtagccg gtgccaacat ccagacgcag caggctggct tgttgatggt
    25681 tgcccagcgg ctgctgtggc gttaaacctg cggcggcaag ctgcgaaatg ctgtacttag
    25741 ttttgaagcc atttggcaag cctggagcct gaccgtttgc cattaccgcg acctgatcgc
    25801 ctttcaccca gccgtgcgct ttgaaatagt tcgccacgct accgatcgca tcaaccggat
    25861 cccacaggtt gatatgcccg tcgccgctga aatctaccgc atattgtttg taagacgacg
    25921 gcataaactg tccgtagccc atcgccccgg caaaggaacc tttcagattg agcggatcgt
    25981 cctgctcgtc gcgcgccatc aacaggaagg tttccagctc gccagagaaa tactccgcgc
    26041 ggcgtgggta gttaaatgac agcgttgcca gcgcatcgag gatgcgagtt ttccccatca
    26101 cgcgccccca gcgggtttca acgccgataa tcccgacgat aatttccggc ggtactccat
    26161 acacctgcca cgcgcgattc aacgcatctt catactgatt ccagaaaacc acaccgttct
    26221 gcacgttgtc cggcgtaata aattttttgc gataacggag ccatgcgccg ttcggacctg
    26281 atggcggttt caccgatgtg gttggtgcct ggttatccat cagccgcagt accgaatcca
    26341 gacgcttcgc ctgggagaga atttcctgca actgctgacg atcgaaaccg tgtttgttca
    26401 ccattttgtc gatgaactgc tgggcattcg ggttattagc gaaatcgccg cccatctgca
    26461 tcacattgtg ctgcggctca agcaggaagc cgccagacgg cgttccggtg gtcgtatcag
    26521 tctcagtagg ttttggcttg ctgctacagg cggcaagcaa cacaaaaagg ggaagcaatg
    26581 ttacataacg acgcttgaac atgaggggtc catttaacag attcaaccag gggcaagtat
    26641 ggtaaagcat cacgccccgc acaaggaagc ggtagtcact gcccgatacg gactttacat
    26701 aactcaactc attcccctcg ctatcctttt attcaaactt tcaaattaaa atatttatct
    26761 ttcattttgc gatcaaaata acacttttaa atctttcaat ctgattagat taggttgccg
    26821 tttggtaata aaacaataaa tcctgaagga gagaacaatg atagaaacca ttactcatgg
    26881 tgcagagtgg tttatcgggc tgttccaaaa gggcggagag gtgtttaccg ggatggtgac
    26941 cggcattctt ccgctgttga ttagcctgct ggttatcatg aacgcactga ttaattttat
    27001 cggtcagcat cgtattgaac gttttgctca acgttgcgcc ggtaaccctg tttcccgtta
    27061 cctactgtta ccgtgcattg gcacgtttgt cttttgcaat ccgatgaccc taagcctggg
    27121 tcgctttatg ccggaaaagt acaaacccag ctactacgcg gcggcctctt atagctgcca
    27181 ctcaatgaat ggcctcttcc cccatatcaa ccctggcgaa ctgtttgttt atcttggcat
    27241 tgccagcggt ctgacaacgc tgaacctgcc acttggccca ctggcggtga gttatctgct
    27301 ggttggtctg gtcaccaatt tcttccgcgg ctgggtgacc gatctgacca ccgccatttt
    27361 tgagaaaaag atgggcattc aacttgaaca aaaagttcac ctggcaggag caacatcatg
    27421 acgcatattc ggatcgaaaa aggaacgggt ggctggggcg gcccgcttga gctgaaagcc
    27481 acgccgggaa aaaaaatcgt ctatatcacc gccggtaccc ggcctgcgat tgttgacaaa
    27541 ctggcacagc ttactggctg gcaggctatt gacggattta aagaaggtga acccgcggag
    27601 gcggaaattg gtgtcgcggt aatcgactgt ggcggcacat tacgctgcgg catctatccg
    27661 aaacgacgta ttcccaccat taatatccac tcgacgggca agtccggtcc gctggcgcag
    27721 tacattgtgg aagatattta tgtctctggc gtaaaagaag aaaacatcac tgtagtaggt
    27781 gatgcgacac cacaaccctc ttccgtgggc cgtgactatg acaccagtaa gaaaatcacc
    27841 gaacaaagcg atggtttact ggcgaaggtg ggaatgggca tggggtccac cgttgcggtg
    27901 ctgtttcaat ctggtcgtga caccatcgac actgtattaa aaaccattct gccgtttatg
    27961 gcattcgtct cggcgctcat tggcatcatt atggcttctg gccttggtga ctggattgcc
    28021 cacggtcttg ctccgctggc gagccatcca ctgggtctgg tcatgctggc gctcatctgt
    28081 tccttcccac tgctttcacc tttcctcggc ccaggcgcag ttatcgcaca ggttatcggc
    28141 gtattgattg gcgtgcagat tggtctcggc aatattccgc cgcatctggc tttaccggca
    28201 ctgtttgcca tcaacgcgca ggcggcctgc gacttcatcc cggtcggttt gtcgctggcg
    28261 gaagcccgtc aggacacggt tcgcgtcggt gtcccttctg tactggtgag ccgcttttta
    28321 accggcgcgc cgactgtact gatcgcctgg tttgtctccg gttttatcta tcaatagagg
    28381 ctgaaacatg accgttattt atcagaccac catcacccgt atcggcgcga gtgccattga
    28441 cgccctcagt gaccagatgc tcatcacctt tcgtgaaggc gcgcctgcgg acctcgaaga
    28501 gtattgcttc attcattgcc acggcgagtt gaaaggtgca ctccatcccg gtttgcaatt
    28561 ttcactcggg cagcatcgct atccggtgac cgctgttggc agcgtggcgg aagacaacct
    28621 tcgcgaactg ggtcatgtca ccctgcgctt cgatggttta aacgaagcgg aatttccggg
    28681 cactgtccat gtggcaggcc ctgtccccga cgatatcgcg ccgggatcgg ttttgaagtt
    28741 tgaatctgtt aaggagtaaa aaatgaatca ggttgccgtt gtcatcggtg gtgggcaaac
    28801 cttaggcgcg ttcctgtgcc acggtctggc tgccgagggg tatcgcgtcg cggttgtcga
    28861 tattcagagc gacaaagccg caaatgtggc acaagaaatt aacgccgaat atggtgaaag
    28921 tatggcgtac ggttttggtg ctgacgccac tagcgagcaa agcgttctgg cgctctctcg
    28981 tggggtagat gaaatctttg gtcgcgtgga tttgctggtc tacagcgccg gaatagcaaa
    29041 agcagccttt atcagcgact tccagctcgg cgattttgac cgttcgctac aggtgaatct
    29101 ggtgggttat ttcctgtgtg cgcgtgaatt ttcgcgtttg atgatccgcg acgggattca
    29161 ggggcgcatt attcagatca actcgaaatc cggcaaagtg ggcagcaaac acaactctgg
    29221 ctacagcgca gcgaaatttg gtggcgtcgg gctgactcaa tcactggcgc tggatctggc
    29281 ggagtacggc attacggtgc attcactgat gctcggtaac ctgctgaaat cgccgatgtt
    29341 ccagtcactg ttgccacaat acgcgaccaa gctgggtatc aaaccggatc aagtcgagca
    29401 gtattacatc gacaaagtac cgctcaaacg cggctgcgat tatcaagatg tgctgaatat
    29461 gctgctgttc tacgccagtc ctaaggcgtc gtactgcacc ggacagtcga tcaatgtcac
    29521 cggcggtcag gtgatgttct gatcaacagc ggagatccat taaggatctc cgtgagacta
    29581 tagaatgcct gatgcgctac gctcatcagg catacaggac ttccgccact acattaagga
    29641 aaagttatgg tatccgcact catcaccgtc gccgttatcg cctggtgtgc gcaactggcc
    29701 ttaggcggct ggcaaatttc tcgttttaac cgtgccttcg acacactatg ccagcaaggg
    29761 cgggttggcg tgggccgttc cagcgggcgc tttaaaccgc gggtcgtggt cgccatcgcg
    29821 ctggacgatc agcagcgcat cgtcgacacc ttgtttatga aaggactgac cgtcttcgcc
    29881 cgaccgcaaa aaattcccgc aattaccggt atgcatgcgg gtgatttaca gcccgatgtg
    29941 atctttcccc atgatccact atcacagaat gctctatcat tggcgcttaa actgaaacgt
    30001 ggataatttc gttgtgaatg ttacttgctt gcgaagttat cattttgaaa cctaaatcag
    30061 gtaatcacgc ccatgaaacc tcgtcagcgt caggccgcca ttctggagta tctgcaaaag
    30121 cagggtaaat gctcggttga agaattggcg caatactttg acaccacagg cacaaccatt
    30181 cgcaaagatc tggtcattct ggaacatgcc ggaaccgtca ttcgtactta tggcggagtg
    30241 gtgttgaata aagaggaatc cgatccgcct atcgatcata aaacactcat caacacccac
    30301 aagaaagagc tgattgcaga agctgccgtt agttttatcc atgatggcga ttcgatcatt
    30361 cttgatgctg gcagtaccgt tttgcagatg gttcccctgc tctcgcgctt taataacatc
    30421 acggtgatga ccaacagcct gcatatcgtc aatgcgctat ccgaactgga taacgaacaa
    30481 actatcctga tgccaggcgg aacgtttcgc aaaaaatcgg cctcatttca cgggcaactg
    30541 gcagagaatg ccttcgagca tttcaccttc gataaattgt ttatgggcac cgacggcatc
    30601 gatctcaatg cgggcgtaac cacctttaac gaggtttata ccgtcagtaa ggcaatgtgc
    30661 aatgccgcgc gcgaagtgat tttgatggcg gactcatcaa agtttggccg taaaagcccc
    30721 aacgtagttt gcagtcttga aagcgtcgat aagctgatta ccgacgcagg tatcgatccg
    30781 gcgtttcgtc aggcgctgga agagaaaggg atcgatgtga tcataaccgg agagagcaat
    30841 gagtgaagca ctactgaacg cgggacgtca gacgttaatg ctggagttgc aggaagcaag
    30901 ccgtttaccg gaacgtctgg gcgatgattt tgttcgcgcc gccaatatca tcctgcactg
    30961 tgaaggcaaa gtggtggttt cgggaattgg caaatcgggc cacattggta agaaaatcgc
    31021 cgcaacgctt gccagtaccg gcactccggc tttttttgtc catccggcag aagcgctgca
    31081 cggcgatctg gggatgatcg aaagccgcga tgtgatgctg tttatctctt actccggtgg
    31141 cgcgaaggaa ctggatctga ttattccgcg tctggaagat aaatctatcg cgctgctggc
    31201 gatgaccggc aaaccgacgt caccgctggg cctggcggca aaagcggtgc tggatatctc
    31261 cgtagaacgc gaagcctgcc cgatgcacct tgcgccgacc tccagcaccg tcaataccct
    31321 gatgatgggt gacgcgctgg cgatggcggt catgcaggcg cgcggattta atgaagaaga
    31381 ttttgcccgc tcccacccag ccggggcact gggcgctcgc ttgctgaata aagtgcatca
    31441 tctgatgcgc cgtgacgatg ccatcccaca ggtggcgtta accgccagcg tgatggatgc
    31501 gatgctggaa ctcagccgca ccggtctggg gctggtggcg gtatgtgacg ctcaacaaca
    31561 ggtacaaggc gtctttaccg acggcgattt acgtcgctgg ctggttggcg gcggcgcact
    31621 caccacgcca gtcaatgaag cgatgacggt cggcggcacc acgttgcaat cgcaaagtcg
    31681 cgccatcgac gccaaagaga tcctgatgaa gcgcaaaatc actgccgcac cggtggtgga
    31741 tgaaaacggc aaactcaccg gcgcaataaa cctgcaggat ttctatcagg ccgggattat
    31801 ttaatccttc aatcccagac gtttcgccag ccgatgcagg ttggcgacgt cggtttccag
    31861 catccgcgcg caggcagccc agttgtgatg attttgtgcc agtgcctgac gaatagtttc
    31921 acgctggaac gcttctgtcg cttcacgcag gttttgctta acaacgggca ccgccgccac
    31981 ttctggcgtc ggcaacgtca cctcaggaaa agcaaaatgt tgcgcctcaa gaatcacttc
    32041 atcgccgctg cgggtggctc tcgccagaac taccgcccga tgaatagcat gttccagttc
    32101 gcgcacgttt cccggaaaac tgtagtgttg cagtaaattt cgcgctccgg cacttaatac
    32161 cacgcgggag agcccctgcc gcaaacgaca ctgctcgcag aaataccccg ccagcagaat
    32221 gacatcatcg ccccgctcac gcagcggcgg caccgaaagt ggaaacacgc tcaggcgatg
    32281 aaacaaatcg gcgcggaatc gccctgccag cacctcttcg cgtaaatcgc ggttagtcgc
    32341 cgccagcacg cgcacatcga cccgcaaaca acggtcatcg ccaacgcgct gaatatcgcc
    32401 atactgcaac accctcagca gcttggcctg caatgccaac gacaactcgc cgatctcatc
    32461 cagaaacagc gtgccgttat ccgccatttc aaacttcccg ctgcgattac tgatagcgcc
    32521 agtaaacgct cctttcacat gcccgaacaa ctcactttcc gccacacttt ccggcagtgc
    32581 agcacagttg agatagacca gcggattcac cgcccgtggc gaggcttcat gaatcgcttt
    32641 cgccaccagc tccttaccgg ttccagtctc accgctgatc aggacgttga gatcggacgc
    32701 cgccacaatc tcaatctctt ttttcagttg cgtcatgcca ggggacaagc caatcatctg
    32761 cgtctgtttc accgcttcaa acggcgtggc atcgcctggc agcatattct ggctttccag
    32821 ttgttcaatc agcaacgcat tgcttaacgc tcccgccgcc agcgcagcaa tcagccgtag
    32881 ctcttcgtcg ctgaaaacat cgaactgatc gggctgcatc ccgtcgagcg tcagtgcgcc
    32941 gatcaggttt tgcccggcaa acaatggcag accaacgcag gcgtgaacct tcagactctc
    33001 ctgcccagga atcaaaccgt catagggatc gggcaattcg ctgtctgcgg gaaagcgcac
    33061 cacatccccg gcgcgggcaa tcgcttccag ccgtggatgc ccttccagcg caaagcgtct
    33121 accgagtaca tcctttgcca gaccgtcgat ggcaagcgga ataaactgcc gcgaatcgta
    33181 acgtagcaac gcagacgcat cgcactccag cacctgacgt agcgtggtga tcaggcgctg
    33241 aaaacgatcc tggtgaccaa tcccacgctg caattcgatg gcgatattcg ccagcacatc
    33301 aacggaaaaa ctcatctttg cctcactgtc aatttgacta tagatattgt catatcgacc
    33361 atttgattga tagtcatttt gactactcat taatgggcat aattttattt atagagtaaa
    33421 aacaatcaga taaaaaactg gcacgcaatc tgcaattagc aagacatctt tttagaacac
    33481 gctgaataaa ttgaggttgc tatgtctatt gtggtgaaaa ataacattca ttgggttggt
    33541 caacgtgact gggaagtgcg tgattttcac ggcacggaat ataaaacgct gcgcggcagc
    33601 agctacaata gctacctcat ccgcgaagaa aaaaacgtgc tgatcgacac cgtcgaccat
    33661 aaattcagcc gcgaatttgt gcagaacctg cgtaatgaaa tcgatctggc ggatatcgat
    33721 tacatcgtga ttaaccatgc agaagaggac cacgctgggg cgctgaccga actgatggca
    33781 caaattcccg atacgccgat ctactgtact gccaacgcta tcgactcgat aaatggtcat
    33841 caccatcatc cggagtggaa ttttaatgtg gtgaaaactg gcgacacgct ggatatcggc
    33901 aacggcaaac agctcatttt tgtcgaaaca ccaatgctgc actggccgga cagcatgatg
    33961 acttacctga caggcgacgc ggtgctgttc agtaacgatg ctttcggtca gcactactgc
    34021 gacgagcatc tgttcaacga tgaagtggat cagacggagc ttttcgagca gtgccaacgt
    34081 tactacgcca atatcctgac gccgttcagc cgcctggtaa cgccgaaaat taccgagatc
    34141 ctgggcttta acttaccagt cgatatgata gccacttccc acggcgtggt atggcgcgat
    34201 aacccgacgc aaattgtcga gctgtacctg aaatgggcgg ctgattatca ggaagacaga
    34261 atcaccattt tctacgacac catgtcgaat aacacccgca tgatggctga cgctatcgcc
    34321 cagggaattg cggaaaccga cccacgcgtg gcggtgaaaa ttttcaacgt cgcccgaagc
    34381 gataaaaacg aaatcctgac caatgtcttc cgctcaaaag gcgtgctggt cggcacttcg
    34441 acgatgaata acgtgatgat gccgaaaatc gccgggctgg tggaggagat gaccggatta
    34501 cgcttccgta acaaacgcgc cagtgctttc ggatctcacg gctggagcgg cggtgcggtg
    34561 gatcgtcttt ccacgcgcct gcaggatgcg ggtttcgaaa tgtcgctcag cctgaaagcc
    34621 aaatggcgac cagaccagga cgctctggag ttatgccgtg aacacggtcg cgaaatcgcc
    34681 cgtcagtggg cgctcgcgcc gctgccgcag agcacggtga attcggtggt taaagaagaa
    34741 acctctgcca ccacgacggc tgacctcggc ccacggatgc agtgcagcgt ctgccagtgg
    34801 atttacgatc cggcaaaagg cgagccaatg caggacgttg cgccaggaac gccgtggagt
    34861 gaagttccgg ataacttcct ctgcccggaa tgctccctcg gcaaagacgt ctttgacgaa
    34921 ctggcatcgg aggcaaaatg agcaacggca ttgtgatcat tggttcgggc ttcgccgccc
    34981 gacaactggt gaaaaatatt cgcaaacagg acgccactat tccattaacc ttgattgccg
    35041 ccgacagcat ggatgagtac aacaaacctg acatcagcca tgttatcagt caggggcaac
    35101 gtgccgatga ccttacccgc cagacggcgg gtgaatttgc cgagcagttt aatctgcacc
    35161 tgtttccaca aacctgggtg acggatatcg atgccgaagc ccgtgtggtg aaaagccaga
    35221 ataatcagtg gcaatacgac aagctagtac tggcaaccgg tgccagtgcc tttgtcccgc
    35281 ctgtgcctgg gcgtgagtta atgctgacgt taaatagtca gcaagagtat cgcgcctgtg
    35341 aaacgcaact gcgggatgcc cgacgcgtgt tgattgttgg cggtggtttg attggtagcg
    35401 aactggcgat ggatttttgt cgtgcaggca aagcggtcac gctaatcgac aacgctgcca
    35461 gtattctggc gtcgttaatg ccaccggaag taagcagccg cttgcagcat cggttgacgg
    35521 agatgggcgt tcatctgctg ttgaaatctc agttacaggg gctggaaaaa acggattctg
    35581 gcattcaggc aacgctggac cgccagcgca atatcgaagt ggatgcggta attgccgcca
    35641 ccggactgcg cccggaaacc gccctggcac gacgcgccgg gctgacgatt aatcgcggcg
    35701 tttgcgtcga tagttatctg caaaccagta ataccgatat ttacgcgctg ggcgattgcg
    35761 cggaaattaa cggtcaggta ttgccgttcc tccagccgat tcaacttagc gcgatggtgc
    35821 tggcaaaaaa tcttctcggc aataacacgc cgctgaaact cccggcgatg ctggtgaaaa
    35881 tcaaaacgcc ggaattaccg ctgcatctgg caggcgaaac ccagcgtcag gatttacgct
    35941 ggcaaattaa taccgaacgc cagggaatgg tggcgcgcgg cgttgacgat gctgaccagc
    36001 ttcgcgcctt tgtggtcagt gaggatcgga tgaaagaggc atttggattg ttgaaaacat
    36061 tgccgatgta ggtgggctac tgtgcctaaa atgtcggatg cgacgctggc gcgtcttatc
    36121 cgacctacgg ggacgcatgt gtaggccgga taaggcgttt acgccgcatc cggcaatggt
    36181 gtccaaatgc aacacgtttt atccgttctg gacttcaccc gctaaccaac gcgccgcagc
    36241 aataaccccc tgccccagag acaaaccgcc atcacccgcc ggtaaactct gtggaaagag
    36301 caatgtgaaa tcagcgagat aatgcgccag acgtgcacgc agcaaacggt tatgaataac
    36361 cccgccgcta aataccagcg tagtgatacc acgcatcgtg gcctgctcac gcatcaacgc
    36421 ggcaaaaccc tgcgccagcg catcatgaaa cgcccacgcg cgttgattaa ccggtgcctg
    36481 ccagttcagc cactgctgcc agaaagtggc gagatccagt tgattgtcca cccgcggcat
    36541 tgtcaccgga tgcgtcactc cgtggcatga ggctgcgagc gcctccagag cacaagccgc
    36601 ttcaccttca taacttaacg tggctggcgc acagcccagt gccgccgcca ctgcatcgaa
    36661 aaaacgccca cacgatgacg ccagcggcgc gttaattcca cgctcaatgg cccgcgccag
    36721 cacgctccag ttttgctgtt gcacactcgc tgtttcggga taattctgcc actccggcac
    36781 aaagcgcagg cactgcgcca gcaggtttcg ccacggctgc ttcgccgcca aatcgccacc
    36841 agcaagcgcc actgcaggca agccgcccag gtgctcacat tcgcgatagt tcacccgcag
    36901 gcactcgccg ccccacaaag cgccattctc ccccataccg ataccgtcga gcgtcaaagc
    36961 aatgacatca ccgccatcca gcggccactg atgctctgcc agacacgccg ctgcgtgggc
    37021 atgatgatgc agcaccgttt gcgtcggcag attcatttcg cgcgcccact ggctggagac
    37081 atagcccgga tgtgcgtcat gcacaacgta ttgcggggtg aaatcgtaga tgttttgcat
    37141 caggcgtaac gcttcgcgcc actgcatctg gatgccatcg tcacttaaat cgcccagatg
    37201 ctgactcaac accgcttgtt caccgcgcac caggcagaag gtatttttca gatccgcgcc
    37261 gagacacagc acaggcggaa catttttaaa gcccggaggc aaagccagcg catccggcac
    37321 atacccccgc gaacggcgca gcatttcgcc gctttcgcgc accaccgaat catccatccg
    37381 ctgcacgatg tcgcggttat gtatcaaaaa tccgtcggca atgccctgca aatccgccag
    37441 cgcctgttcg ttgctgatag ctggtggttt accgctcagg ttgccggagg tcatcaccag
    37501 cgggcattgc agttcctgta acagcaaatg ctggagcggg ttcgcaggca acattacccc
    37561 gacttcgtta aggtcagggg cgatatcatc acaaagctca ggaacgtatt ttttatccac
    37621 cagcacaatc ggcgcggcgg gcgtggtaag caactggcgc gcagcgtctg gtaaaccgtc
    37681 agccactggc aacatgaccg ccagcggttt cgccgggcga tgtttgcgcg cccgaagtgt
    37741 cgccaccgcg ttactgttac gtgcatcgca ggcaagatga aatccgccaa tccctttgat
    37801 ggcgacaatt ttgcccattt ttaactgtgc gatagctgcc tgtaatgccg cctcttgttc
    37861 cgcatgttca ccatgactta cccattcaag atgcgggcca cactccgggc aggccaccgg
    37921 ctgggcgtgg aagcgacgat cgagcgggtc acggtactct ttgtcacagg ccggacatag
    37981 cggaaacgcc gccatcacgg taaacgggcg gtcgtaaggc atggcgcgaa taatggtgaa
    38041 acgcgggccg cagtgggtac agttgataaa cggataacga taacgccgtt cgcctggggt
    38101 attcatttcg gcaaggcaag cagggcaagt agcggcatcg ggaacaattt gcgtattcat
    38161 ggtgccgcct gtgctctggc gtatagtgaa ctcggtgggc agttgtgacc agataaacgg
    38221 ctcacgctcg acgctatcaa tacgcgccag cggcgggcag tgctgataca attgaacaag
    38281 aaacgtttcc gggtcttccc gcagccggac ttctacgcca tcgccgtcat tacagacatc
    38341 gccgtgaaga tttaattgct gtgccagctg ccagacaaac ggacgaaaac cgacgccctg
    38401 cactttgcca cgaatacgca gttggacacc gcaagatgtg ttttttgcca ttgagttatt
    38461 cccgccatca tgaattgcgt aacccgccct gccggacacg acagcgtcgc atccggcagt
    38521 cacaggtcgg cgataccgcc cgctccgtat tctacgaata tttccgggaa ttcctttgat
    38581 gccagaacag ttctgtaaga tttttagaac atcagcgccg tacggcggcg tttttctgcg
    38641 ctcagttgtt caagtttatt acgatcgaca caaatcagcg catgagtcgg gcaagccgcc
    38701 atacacgccg ggccgtcttc acgatggttg cacaggtcgc atttattggc ttcggctttg
    38761 tcagcccgta cattcagacc cgcgccgctg ttgcggatca ccggacgtac caccacttcc
    38821 atcgcaccat acgggcaagc cacaacgcag gttttgcaac caatgcaacg ttcctgcatc
    38881 acatgaacaa accctttatc acggctgata gcaccattcg ggcagacgtt agcgcacggt
    38941 gcatcttcac actgacggca aactgtcgcc gtggaaatgt tcacaccttt aatgacatgg
    39001 atacgcggta aaaaagtttc cggggtcagc gatgcacagt cctgattttc ctgatgagaa
    39061 accacgcacg ctacttcaca ggtacggcaa ccaatacatt tactcgcgtc agcaatgatg
    39121 aaacggttca tcaaattctc cagcaatgac agttaatgcg ccgatacatt cacaaatcat
    39181 gccagttttt aatttactgt tatttaagga aattaatttc tgtaatgcag gaaaaacgat
    39241 gtcatcgaca ctagtgacga tgacatgtga tgacaatgtt tatcgcgaag gagcaatgag
    39301 tgagtcgcgg cggatcagtt ttccgctgaa ggttttcggc ggtgagaaat ccccgccatc
    39361 gagcataaaa atcagccgtc caataatttc ctgaatcatc tcagtcaccg gaatttttac
    39421 gctggagagc gccggaacgg tgtagggggc aatagcgata tcatcgaatc cgataactga
    39481 cacctgctct ggcaccgcta cgccgcgctc gtgtaacgct ttcatcgcac ctatcgccat
    39541 atcgtcgtta ctggcaacta acgcgctaaa tttagcccca cgttcgagca acatttctac
    39601 cccttcggcc ccgctggcag gcgtccattt accgttagcg ataagttttt cattgagcgc
    39661 aataccatgc tgcgccagcg cgtctttata cccggcaaga cgttcaatgc tggtggggga
    39721 atccatcgag ccggtaagga aagcaatctc ctgatgcccg gcgtttatca actctgccac
    39781 ggcgttaaaa ctggtctgtt tatgatcgca ccagacgcta tggctgctgt ttttgcgcag
    39841 gcggcgatta agcaccatta tcggctgact gtgcgcgtca atgatgtcat cgatctcatc
    39901 cacgcttaaa aaacgcgggt aaatcatgat cgcgtcgcag cgcagatcca gcagatactg
    39961 aatcgcctgg cgctcttctt ctgcgctgtg tttaccatct gccaatagca actgccgccc
    40021 tttctcttcc gccattcgcg cggcatgaaa gagtaattca ctaaaataaa tgccgtggta
    40081 aagcgtgttg gtcactacca gccccagcgt ctgagtactc ttcgccgaca gattgcgcgc
    40141 cagcaagttt ggacggtaac cgctctcttc taccgcctga aacacgcgat ctttagtctc
    40201 ctggctgacg tagccattac ctgaaagcac gcgggaaacg gtcgcttttg aaaccccggc
    40261 gcgcttcgcc acttccagca tcgtcgtcat cattttcatc cctttacacg caatcaacgc
    40321 agtgtactgc accgtttgcc gattgtcctt gcacaatcgg cgggaaaaat attcaggtga
    40381 ccggtttcac aaatataaaa aatgaacaat tcactctctt gcttatttag tgacaactat
    40441 tcatgatttt gtgaaaccgg tttcttaatt ccgtttcagc atcggcattt ttccgtcacg
    40501 tcgactgata acaactacat ctaccctact gataacagga taaaatccga tggccaaaaa
    40561 ttatgcggcg ctggcacgct cggtgatagc ggcactgggc ggcgttgata acatctcggc
    40621 ggtcacgcac tgtatgacgc ggttgcgctt tgttatcaaa gatgatgcac ttatcgacag
    40681 cccgacgtta aaaaccatcc ccggcgtgct cggcgtggta cgtagtgaca accagtgtca
    40741 ggtgattatc ggcaataccg tttcacaagc ctttcaggaa gtcgtcagcc tgctgccggg
    40801 agatatgcag cccgcacagc ccgtgggtaa acccaaactc acgctacgtc gcattggtgc
    40861 gggatcctcg atgcgctgat cggcaccatg tcaccgctga tcccggcgat tatcggcgga
    40921 tcgatggtca aactgctggc aatgatcctc gagatgagcg gcgtgctgac aaaaggatcg
    40981 ccgaccttaa ccattctgaa tgtgattggt gacggtgctt tcttcttcct gccgctgatg
    41041 gtcgcggcat ctgccgccat caaatttaaa accaatatgt cgctggcgat tgccatcgcg
    41101 ggtgtgctgg tacatccgag ttttattgaa ctgatggcga aagcggccca gggtgaacat
    41161 gtcgaatttg ccctgattcc ggtcaccgcg gtgaaataca cctacacggt gatcccggcg
    41221 ctggtgatga cctggtgcct gtcatatatc gaacgctggg tggacagcat tacaccggcg
    41281 gtgaccaaaa acttcctcaa accaatgctg attgtgttga ttgccgcacc gctggcaatc
    41341 ctgctgattg gcccgattgg tatctggatc ggtagcgcca tttcggcgct ggtttacacc
    41401 attcatggtt atctgggctg gctttcagtc gccattatgg gcgcgctgtg gcctctgctg
    41461 gtaatgaccg ggatgcaccg cgtctttacg ccaaccatca ttcagaccat tgccgaaacc
    41521 ggcaaagaag ggatggtcat gccgtcagag atcggcgcta acctgtcgct gggcggttca
    41581 tcactggcag tggcgtggaa aacgaaaaac ccggaactgc gtcagacggc gctggctgcg
    41641 gcggcatcag ccattatggc ggggatttcc gaaccggcgt tatatggcgt ggcgatccgc
    41701 ctgaaacgtc cgcttatcgc cagtcttatc agcggtttta tttgcggcgc ggttgccggt
    41761 atggcggggc ttgccagcca ctcaatggca gcgccggggc tatttaccag cgtgcagttc
    41821 ttcgatccgg cgaatccaat gagcatcgtc tgggtgttcg cggtcatggc gctggcggtg
    41881 gtgctgtcgt ttatcctcac actgttgctc ggctttgagg atattcctgt tgaggaagcg
    41941 gctgcccagg cgcgaaagta tcagagcgta caaccgaccg tcgccaaaga agtaagtctt
    42001 aattgaggat gaaaatgtca gtatttccag aaagtttttt atggggcggc gcgcttgccg
    42061 ccaaccagtc tgaaggtgcg ttccgtgaag gtgacaaagg tctgaccact gtcgatatga
    42121 tcccacacgg cgagcatcga atggcggtga aactggggct ggaaaaacgt tttcagttgc
    42181 gagatgacga gttttatccc agccatgagg cgacggattt ttatcatcgt tataaagaag
    42241 atatcgccct gatggcagag atgggattca aggttttccg tacctcaatt gcctggagcc
    42301 gtctctttcc gcagggcgat gaaatcacgc ccaatcagca gggcattgct ttttatcgtt
    42361 ctgtctttga agagtgtaaa aagtacggta tcgaaccgct ggtcacgttg tgccacttcg
    42421 atgtgccgat gcatctggtc accgaatatg gctcctggcg taaccgcaag ctggtggagt
    42481 ttttcagccg ctacgccaga acctgctttg aagcatttga tggtctggtg aaatactggc
    42541 taaccttcaa tgaaatcaac attatgttgc atagcccgtt ctccggcgcg ggtctggtgt
    42601 ttgaagaagg tgaaaatcag gatcaggtga aatatcaggc cgcgcatcac cagctggttg
    42661 ccagtgcgct agccaccaaa atcgcccatg aggttaaccc gcaaaatcag gtgggctgta
    42721 tgctggcggg cggtaacttc tacccttaca gttgcaagcc ggaagatgtc tgggcggcgc
    42781 tggagaaaga ccgggaaaac ctgtttttta tcgatgtgca ggcgcggggc acgtatccgg
    42841 cttactctgc ccgcgtattc cgcgaaaaag gggtaaccat caacaaagca ccgggcgatg
    42901 atgaaatcct gaaaaacacc gtcgattttg tctctttcag ctattacgcc tcgcgctgcg
    42961 cctcggcgga gatgaacgcc aacaacagca gtgcggcgaa cgtggtgaaa tcgctgcgta
    43021 atccgtatct acaggtgagc gactggggct ggggaattga tccactcggt ctgcgtatca
    43081 ccatgaatat gatgtacgat cgttatcaga agccgctgtt tctggtggaa aacggcctgg
    43141 gcgcaaaaga tgaatttgct gccaatggcg agattaacga cgactatcgc atcagctact
    43201 tacgcgaaca tatccgcgca atgggcgaag cgattgcaga cggcattccg ctgatgggct
    43261 acaccacatg gggctgtatt gatttagttt ccgcctctac gggtgaaatg agcaaacgct
    43321 acggctttgt ctttgttgac cgtgacgacg caggcaacgg tacgctgacg cgcacgcgta
    43381 agaaatcatt ctggtggtat aaaaaagtga ttgccagtaa tggggaagat ttagagtagg
    43441 taacagtgcc ggatgcggcg tgaacgcctt atccggccta catgtcgcac gaaccatgaa
    43501 ggcccgataa gcgcagcgca tcgggcaatt tagcatttgg catcagagct ggttcacccc
    43561 atcaagaaca tccctgtcct gattccttaa tgaaaaacta ctcttcttcc accgctaact
    43621 gcgcgaagcc gccatttctt tcccagcctt ccagtcgttg ataaacggtt tctaccgcat
    43681 ctttaatcgg ctgggtcatc gggtagtaaa agccgacgat atccggctga atgccgagga
    43741 aaatcacttc gccaatatct tctttcaact ggtcgataag gtaattcaac ggcatgttat
    43801 gggtagtcat cataaacatc tcggcgatat catccgggtc gatgatgcgg atctcgccgg
    43861 ggtttagccc catatccgtg gcgtcgacaa tcagcagtcg tgtcgggcgc agttcacgga
    43921 tagcgacgat gtcgttttcc ggtgcgctac cgccgtcaat caccacccag ttacctttcg
    43981 gcgcggcggc gcacttttcc gccagcagcg gacctgcgcc atcatcgccc atcatgctat
    44041 tgccaacaca gagtaaaacg tcagtcacgc agtctcctca ccatcaaata gatggcgttt
    44101 tcctgatgaa tatcatgcag catacttaac agcattgtac tccattcctg ctgctgcgaa
    44161 gtttgcgctg cccgggcttt atcgaatgcg ttggccagca tcggcacatg gttaatgtcg
    44221 atgacgatct caccatattt cggcacgcct tccattttgc ggcgggcttc actgcctgcc
    44281 tccagagtgg caatccatgc cagatattca tcccacgggc aggtgagcgc cgcttccagg
    44341 caatcgataa ccccaaggtg gtgaccaatc gccaggctgt aatagaccac ctgctgcgcc
    44401 tcggcgggcg tggcatcgtt ctcatcaata aatttacggc tcagttgact gaacaccacc
    44461 ttttcactca tcggatacgc gcctcttcaa caacatgatt cagatggctg acaatctcgt
    44521 tcagacgcgg atcgttttcc gcttccagcc agcgtgcaac ctgttcttcg ccctgcccta
    44581 actgtgtaag gtaatcatcg gcaatctgac gaccgtaacg ataacccgcc aggcgacgtg
    44641 cttcgcgatc cactttcacg cgcagcggct gcaccatatc gccatgcagg atctccgccg
    44701 gttgttcatc cagttcaccc ggcccacggg cgtgaatttt ctgctccagc aggccgagcg
    44761 ccattgcaaa gccgtacagc gtggcggcag gcgttggcgg gcagccaggg atataaacat
    44821 ccacagggac aattttatcc gtaccgcccc acacacagta gagatcgtgg aagatcccgc
    44881 cgctgttacc gcaggcaccg taggagatac aaattttcgg gtccggcgcg gactgccacg
    44941 cacgcagcgc aggggatcgc attgcacggg tgaccgcgcc ggtaaacagt aaaatatccg
    45001 catgacgcgg tgaaggaacg actttaatgc cgaagcgttc tgcatcaaac agcggcgata
    45061 aagtggcgaa aatttcgatt tcgcaaccgt tgcagccgcc gcagtccacg cggtaaacat
    45121 aggcagaacg tttgattttt ttcagtaacg acgccttcat gctggcgatg gattcatcca
    45181 ccgtcatggg gaccggaatg ccgttggcgt cacgggggcc taataaattg ctcatcagat
    45241 ggcctctttc atatggcgag tcagttcaat acggtcggac ggcaccaggc atttctggcg
    45301 cttacattcc gggcaagtct caaagctttc gcggtggttt tccgcgcggc tgtcgccgtt
    45361 gtgcttaagc agcgcaatgg cgtagtcgat ctctttctgg acggcgaaag gacgattgca
    45421 gacgcggcag ttgcacagcg cgaagcggga ctgttgcagg aagtcttctt tcttccacac
    45481 cgccagttcg tactcttgcg acagtttgat cgccgccgtc gggcagactt cttcgcagcg
    45541 tccacagaag atgcagcgcc caagattaaa ctcccaggca agctctcctg tggcgaggtc
    45601 agtttcaacc gttaaggcgt ttgacgggca ggcattgacg caggccgcgc agccgatgca
    45661 ctgctgcggg ttctgctctg gcttaccacg gaagttttta tcaaccgcaa tcggctccag
    45721 cggataagac gaggtcgccg tgccggtttt gatgactttt ttgataaagg taaacatggc
    45781 gattccttat ttcagcggcg agtttttacg ctcaatgctg taacgctcga gttctttgta
    45841 cggcaccact ttgctcttct tcttacgcac atcgaccacg gtcatgcggt cggtacagga
    45901 gtagcaaggg tcgaggctac cgataatcag cggcgcatcg gaaacggtgt tgccgcgcag
    45961 catgtagcgc agggtcggcc agttcgcgta ggtcgcggca cggcagcgcc agcggtacag
    46021 cttctggttg tcgccggtca tgctccagtg gatatcatcg ccgcgcggcg cttcggcaaa
    46081 gcccagcgca aagcggtgcg gaatgtaggt aaagccttcc accatcagtg ggccacccgg
    46141 caggttatcc agaccgtagt cgatcatgtt cagcgcggta tagacttcgt tgatacgcac
    46201 tttcagacgg gaaataacgt cgcagccctg ctcgctgtgg acttccattg gcagcaggcc
    46261 atagccgaca aacgggtgat cggcgcgggt atcacgggcg tgaccgctgg cacggaccat
    46321 cgggccgacg ttactgaagt cgcgagcgat ttccgggtcc agacgaccaa tgccgacagt
    46381 gcgctgttcc atgttcggag tgctcagcag cacatccacc agctcctgca cttcacgacg
    46441 catctgttgt gccagctggc gggtctggat catgtcgtct ttcagcagat cgcgacgaat
    46501 cccgccgatc aagttcaggc cgtaggtttt acgcgcaccg gtaaggatct ctgccatttt
    46561 catggaggtt tcacgcacgc ggaagaactg cataaagccg gagtcgaagc cggtaaagtg
    46621 acaggccagg ccaaggttga gcagatgcga gtgcaagcgt tctacctcca gcagaatggc
    46681 gcggatcatc tgcgcacgtt ctggcacctg aatacccatc gcgttttcca ccgacgtggt
    46741 gtaggcggtg ctgtgggcaa agccgcagat cccgcacaca cggtcagaga ggaaggtcac
    46801 ttcgttataa cccatacggg tttccgccag tttttccatg ccgcgatgga cgtagaacag
    46861 acggtagtcg gcgtcgataa tgttttcgcc atcgacgaac agacggaagt ggcccggttc
    46921 atcagaagtg acgtgcagcg gaccaatcgg cacgacgttg tttttcttgt cgcccagttc
    46981 gttgatgaac tcgtaggttt cagcatcggt ggtcggtgcc ggacgctgac gataatccat
    47041 gctgtcttta cgcagcggat aaagttcatc cggccagtca tccggcagca ccagacgacg
    47101 ttcatccggc agaccaaccg gaatcaaacc gtacatatcg cgcacttcac gctcgcccca
    47161 caccgccgcc ggaacgcgcg gcgtcacgga cggatattcc ggtttgttgg cgtcaacttc
    47221 gacgcgaacc gtaatccaac acttagtgcc cttctccatc gacagcacgt agtaaacggc
    47281 gtaatgacca ttcagtttgc gttcgtcgtt accaaacagc accgacagcc agccaccctg
    47341 tttgtagtaa agaaactcca ccacttccgg caggtagttc acctttacgg tgacagtcag
    47401 ctgatctttg gtctgccagg cgtggtccag cacgacgccc ggaaatgcct cattcagcgc
    47461 ggcgagataa tgttgaccta atttttcttc agacatgctc aaactctctt taatcacgcc
    47521 gccagcaagg agacgaacgc taaaaatgca aagccaaacc cagcccaggt aatgcgcgga
    47581 gtaatatcaa gacgcagacg ggccatgctg ttttcgaaca gcgcgataac caggacgccg
    47641 accaccagtt ttacgatggc aatcaccagc gccagcagca gtccaccggc ggtgaaggtt
    47701 tccatttgtc cccacggaat aaacaccccg acgaacatct gcaacaccac cagctgtttc
    47761 aggctgatac cccatttcat gacgccaaag ccgctgccgc tgtattcaga gagcgggcct
    47821 tcctgcagct cctgctcggc ttccgccagg tcgaacggca gtttgcccat ttcgataaag
    47881 gtggcgaacg cacaggcaca aagcgccagt accagcggga tgctctggct cagcggccag
    47941 tgataaacgg tgtcggtgat gttgctgatg ttggtggaac cggcaacctg tgcggcaacc
    48001 cacagaccaa gcagcagcat cggttcgacc agcacgccaa gcatcgcttc acggctcgcg
    48061 ccgatagcgg taaacgggct accggtatcc agaccagaaa tggcaaagaa gaaacgcgcg
    48121 atggcaaaga gatacagtaa ggtgatcaaa tcacccagtt gcggcagcgg agaaccgacg
    48181 gtcaccaccg gcagcgcagt agcgatagtc agcatgacgc ccaccatcac atacggcgtc
    48241 aggcggaaca cccagccgga ggcatccggg ccaacgctct ggcggcccag cagtttgaaa
    48301 atgtcacgat actcctgcaa cacacccggc ccacgacggt tatgcagacg ggcgcgcgcc
    48361 acgcgggtaa taccggagag cagcggcgca acggcaaata acaccagcgc ctgaattaac
    48421 ggatataaaa cactcattct caggctcctc gtgaaacaat aatcaccacc agtaccgcca
    48481 gttcaaccag cgccatccgg cggaacagca acgcactacc ttcgcactgc cagcccggca
    48541 ccagcgacac cggattcagc catttgcgca gtttcagcac tggcgcaaac gcctgtttca
    48601 ccggcatggc aaaaccgtga gcggtaatca ccattgattt ttcgtggtcg tagccgcaca
    48661 cccaggccgc gccgcgggaa cgcgatggca aacgatcgcc tttgcaaatc gccataatga
    48721 tgaatggcag cagcgggcag gcaatcagca gcaacgtgat catcggttga gaaacggtgg
    48781 tgttagcagg ctccagcggc agaggtacag cagcagacag catcggcagc agccacggcg
    48841 cagcaacacc gccaattacg cagcaaatcg ccagtgccac tacgcttacg ctcatcagga
    48901 gcggtgcaca ggtggcgttt tcggcttctt tggtacgcgg cgcgccgagg aacgtgacgc
    48961 catagacttt cgccatacac atcaccgcca gcgcaccggt aattgccaga cccacggcga
    49021 gcagcggccc cagcagacgg gcaacaaacg cgccactatt gctcagtttg aagaaggatt
    49081 gatagataac ccattccccg gcaaaaccat tcagcggcgg cagcgcagcc attgccatca
    49141 gcccgactaa catggcgatg gagataaccg gcattttctt gccaatacca ccgagttttt
    49201 cgatatcgcg atgaccggta cggaaccaga tgctccccgc tccgaggaac agtacgcttt
    49261 tgaacaggct atggttaagc agatggtaca gaccaccgac caggccaaga gcaatcagtg
    49321 ccggttgttc gagcgcgata cccgttacgc cagcgcccag ccccagcagg ataatgccga
    49381 tattttccag ggtgtggtaa gccagcaggc gctggatgtt gtgttccatc aacgcataca
    49441 gaccaccgac gaacgcggtg atcatgccga gcaccagcag cgcgatcccc caccacagcg
    49501 gtgcattacc gcccagcagt gacagggtta aaatgcccag caggccaatt ttcatgacta
    49561 ccgtagaaaa caacgcggca gctggcgcag aggcgttagc atgtgcctgc ggcacccagc
    49621 cgtgcagcgg aataatcccg gccagcaggc caaagccaat cacaccgagc agccagatat
    49681 cggaaccgag cggcagctgt tgcatacgca tatccagcag gcgcagatcc agcgtgccat
    49741 aacgctgcca cagcagccag caagcaatcg ccagcagcag agtgccaaga cgccccagcg
    49801 caaaccacag tttgccctct ttgctgttgc tggtgaggaa caccgcgcac agggccatga
    49861 tttcggccat taccacgaac atgccgaggt tgctggcaat gacggcgcag acggcggcag
    49921 ccatcaacat attgatctgc aagccgttgc acttcacctg cgcgtggcga tgccagtcaa
    49981 tgttgtagag gctgacaaac agaccgcaca gaccgagcgt aatcagccaa atcgcgttaa
    50041 gcggagaaat ttgcacatcg tagcttacca gcgacagcgc accgctcacg ccaaccgcgc
    50101 cagtcagtac agtgaagccc gcggctgccg tatacagact accaaccgcg ccgccaattc
    50161 cagctatcca gccacttaac gctttttgaa aagaaaagag aaatgccaga acagcggcgg
    50221 cgacaaacca cgccacgccg ctattgatca gggaaattgc gctcatttag cctctccact
    50281 ttgagcctgc tgaaacaagg tgagatcgcc aaagtccgtg ttaaaagtca gctcacgctt
    50341 acgtttgctg acgcgggcga tatcagtgtt atccaccaga tgcagggctt tagtcgggca
    50401 catccgcacg caggccggac cttgttcatc aaagctacaa aggtcacatt tgacggcgat
    50461 cgcgcgaata cctggcaccc agtcaagcaa tgtgctgaca cgcgccggag caggcggtgc
    50521 cggtggcgct ttcggggtat tggcgtttgc cggaatatcc agcggacggc tgccggaaaa
    50581 ttcaattgcg ccaaacgggc aggcgatgcc gcacagcttg cagcttacgc acaggctttc
    50641 attcaactgc acggccccat caacgcgggt gatggcgtta accgggcaga ccaccgcgca
    50701 gggtgcatct tcacagtggt gacagagctg cggcgcagat tctttttcat tcagcatcac
    50761 tctcaggcgc ggcattgatt gcaggccgtg ctggcgatgc gtctctgaac aggcggcctc
    50821 acaagtgtgg cagccgatac agagcgtgga gtcagcaatt acaaaacgat tcaccaggca
    50881 ttcctcaggt gattgtcatt tttgacgaaa acatgccgat gaaatgtcat tttcgacact
    50941 catcgacacg cccatcccca aacaggcgta acgcctgcaa aacgggcaaa gcctcagctc
    51001 atgctgccgg gctttgtccc tttaccagtt ggcttaaatt caccggcaca ttgttttcaa
    51061 tagcggtgta taagctgtcg taaacgccag cgattttttc gagatagtgt tccagaacct
    51121 gttcgcgatc gcggatgttg accttgccat caatcatgcc gtcaatgctc agttgcgcct
    51181 gcgcaatccg ctgtttgtct tcgccatctt ttgtttcgac gtaatactcg atggtgtggc
    51241 tgttaaagcc atccgccagg gtgacgtaaa tgcgaaaatg ttcaaaaagg acgaaacaga
    51301 gttctttgtc cggcgcgcag ctcatggcgt gatgcaggcg cgctttcgat aacgtgatcc
    51361 cctgaaccag cgaattgcag tagatgtgcc actggtcctg taggcgacga tgccgctgtg
    51421 cgatgtaatc ggctttctcg cttatttccc aaatagtcat tgtcaggtta cccgtttaac
    51481 agagatgcca gctttaagca ttttttgtgc caacttttaa tttattgtta ttaaagagat
    51541 ttttaagcta aagatgaatt tcgtcgccgt gtcgacgtgt catttcgaca tcatcgacat
    51601 tattcaccgc agggataatc aacactggca caattattgc ttgtagctgg caatagttaa
    51661 tgggaggcga tatgcacgaa ataaccctct gccaacgggc actggaattg atcgaacagc
    51721 aggccgcaaa acacggcgca aaacgcgtaa ctggggtctg gctcaaaatt ggcgcatttt
    51781 cttgtgtcga aaccagctct cttgcctttt gttttgatct ggtttgccgc ggcagcgtgg
    51841 cggaaggttg taaactgcac ctcgaagaac aagaggccga atgctggtgt gaaacatgcc
    51901 aacagtatgt gacgctactg acccagcgcg tccgccgctg tccacagtgt catggtgaca
    51961 tgctgcagat tgtggcagac gacggtttac agattcggcg gatagaaata gaccaggagt
    52021 gagcgatgtg tacaacatgc ggttgcggtg aaggcaacct gtatatcgag ggtgatgaac
    52081 ataaccctca ttccgcgttt cgtagcgcgc catttgcccc ggcggcacgc ccgaagatga
    52141 aaatcaccgg cattaaagcg cctgaattta cccccagcca gactgaagaa ggcgacctgc
    52201 attacggtca tggcgaagcg ggcactcacg caccgggcat gagccagcgt cggatgctgg
    52261 aagtcgaaat tgacgtgctg gacaaaaata accgtctggc tgaacgcaac cgcgcgcgct
    52321 ttgctgcccg caagcaactg gtgctcaacc tggtttccag ccctggttcc ggtaaaacca
    52381 ccctgctgac ggaaacccta atgcgcctga aagacagcgt tccgtgcgca gttattgaag
    52441 gcgaccagca aaccgtgaac gatgccgcac gcattcgcgc taccggcaca ccagcgattc
    52501 aggtgaatac cggtaaaggc tgccatcttg acgcacagat gattgccgac gccgcaccgc
    52561 gcctgccact ggacgataac ggtattctgt ttatcgaaaa cgttggcaac ctcgtatgcc
    52621 cggccagctt cgatctcggt gaaaaacaca aagtggcggt gctttccgtt accgaaggtg
    52681 aagacaaacc gctgaaatat ccgcatatgt ttgccgccgc ctcgctgatg ctgctcaaca
    52741 aagttgacct gctgccgtat ctcaactttg acgttgagaa gtgcatcgcc tgcgcccgcg
    52801 aagtcaatcc agaaattgaa atcatcctta tttccgccac cagcggcgaa gggatggacc
    52861 agtggctgaa ctggctggag acacagcgat gtgcataggc gttcccggcc agatccgcac
    52921 cattgacggc aaccaggcga aagtcgacgt ctgcggcatt cagcgcgatg tcgatttaac
    52981 gttagtcggc agctgcgatg aaaacggtca gccgcgcgtg ggccagtggg tactggtaca
    53041 cgttggcttt gccatgagcg taattaatga agccgaagca cgcgacactc tcgacgcctt
    53101 acaaaacatg tttgacgttg agccggatgt cggcgcgctg ttgtatggcg aggaaaaata
    53161 atgcgttttg ttgatgaata tcgcgcgccg gaacaggtga tgcagttaat tgagcatctg
    53221 cgcgaacgtg cttcacatct ctcttacaca gccgaacgcc ctctgcggat tatggaagtg
    53281 tgcggtggtc atacccacgc catttttaaa ttcggcctcg accagttact gcctgaaaac
    53341 gttgagttta tccacggtcc gggttgcccg gtgtgcgtac tgccgatggg tagaatcgac
    53401 acctgcgtgg agattgccag ccatccggaa gtcatcttct gtacctttgg cgacgccatg
    53461 cgcgtgccgg ggaaacaggg atcgctgttg caggcaaaag cacgcggtgc cgatgttcgc
    53521 atcgtttact cgccaatgga tgcgttgaaa ctggcgcagg agaatccaac ccgcaaagtg
    53581 gtgttcttcg gcttaggttt tgaaaccacc atgccgacca ccgccatcac tctgcaacag
    53641 gcgaaagccc gcgatgtgca gaatttttac ttcttctgcc agcatattac gcttatcccg
    53701 acgctgcgca gtttgctgga acagccggat aacggtatcg acgcgttcct cgcgccgggc
    53761 cacgttagta tggttatcgg cactgatgcc tataatttta tcgccagcga ttttcatcgt
    53821 ccgctggtgg tcgctggttt cgaacccctt gatctactgc aaggcgtggt gatgctggtg
    53881 gagcagaaaa tagcggccca cagcaaggta gagaatcagt atcgtcgggt ggtaccggat
    53941 gccggtaacc tgctggcgca acaggcaatt gctgatgtgt tctgtgtcaa cggcgacagc
    54001 gaatggcgcg gcttaggcgt gattgaatct tctggcgtgc acctgacgcc ggattatcaa
    54061 cgattcgatg ccgaagcaca tttccgcccg gcaccgcagc aggtctgcga tgacccgcgc
    54121 gcacgttgtg gtgaagtatt aacgggcaaa tgtaagccgc atcaatgccc gctgtttggt
    54181 aacacctgta atcctcaaac cgcatttggt gcactgatgg tctcctccga aggagcgtgc
    54241 gccgcgtggt atcagtatcg tcagcaggag aatgaagcgt gaataatatc caactcgccc
    54301 acggcagcgg cggccaggcg atgcagcaat taatcaacag cctgtttatg gaagcctttg
    54361 ccaacccgtg gctggcagag caggaagacc aggcacgtct tgatctggcg cagctggtag
    54421 cagaaggcga tcgtctggcg ttctccaccg acagttacgt cattgacccg ctgttctttc
    54481 ctggcggtaa tatcggcaag ctggcgattt gcggcaccgc gaatgacgtt gcggtcagtg
    54541 gcgctattcc gcgctatctc tcctgtggct ttatcctcga agaaggattg ccgatggaga
    54601 cactgaaagc cgtagtgacc agcatggcag aaaccgcccg cacggcaggc attgccatcg
    54661 ttactggcga tactaaagtg gtgcagcgcg gcgcggtaga taaactgttt atcaacaccg
    54721 ctggcatggg cgcaattccg gcgaatattc actggggcgc acagacgcta accgcaggcg
    54781 atgtattgct ggtgagcggt acactcggcg accacggggc gactatcctt aacctgcgtg
    54841 agcagctggg gctggatggc gaactggtca gcgactgcgc ggtgctgacg ccgcttattc
    54901 agacgctgcg tgacattccc ggcgtgaaag cgctgcgtga tgccacccgt ggtggtgtaa
    54961 acgcggtggt tcatgagttc gcggcagcct gcggttgtgg tattgaactt tcagaagcgg
    55021 cactgcctgt taaacctgcc gtgcgtggcg tttgcgaatt gctgggactg gacgccctga
    55081 actttgccaa cgaaggcaaa ctagtaatag ctgttgaacg caacgcggca gagcaagtgc
    55141 tggcagcgtt acattcccat ccactgggga aagacgcggc gctgattggt gaagtggtgg
    55201 aacgtaaagg tgttcgtctt gccggtctgt atggcgtgaa acgaaccctc gatttaccac
    55261 acgccgaacc gcttccgcgt atatgctaat aaaattctaa atctcctata gttagtcaat
    55321 gaccttttgc accgctttgc ggtgctttcc tggaagaaca aaatgtcata tacaccgatg
    55381 agtgatctcg gacaacaagg gttgttcgac atcactcgga cactattgca gcagcccgat
    55441 ctggcctcgc tgtgtgaggc tctttcgcaa ctggtaaagc gttctgcgct cgccgacaac
    55501 gcggctattg tgttgtggca agcgcagact caacgtgcgt cttattacgc gtcgcgtgaa
    55561 aaagacaccc ccattaaata tgaagacgaa actgttctgg cacacggtcc ggtacgcagc
    55621 attttgtcgc gccctgatac gctgcattgc agttacgaag aattttgtga aacctggccg
    55681 cagctggccg caggtgggct atacccaaaa tttggtcact attgcctgat gccactggcg
    55741 gcggaagggc atatttttgg tggctgtgaa tttattcgtt atgacgatcg cccctggagc
    55801 gaaaaagagt tcaatcgtct gcaaacattt acgcagatcg tttctgtcgt caccgaacaa
    55861 atccagagcc gcgtcgttaa caatgtcgac tatgagttgt tatgccggga acgcgataac
    55921 ttccgcatcc tggtcgccat caccaacgcg gtgctttccc gcctggatat ggacgaactg
    55981 gtcagcgaag tcgccaaaga aatccattac tatttcgaca ttgacgatat cagtatcgtc
    56041 ttacgcagcc accgtaaaaa caaactcaac atctactcca ctcactatct tgataaacag
    56101 catcccgccc acgaacagag cgaagtcgat gaagccggaa ccctcaccga acgcgtgttc
    56161 aaaagtaaag agatgctgct gatcaatctc cacgagcggg acgatttagc cccctatgaa
    56221 cgcatgttgt tcgacacctg gggcaaccag attcaaacct tgtgcctgtt accgctgatg
    56281 tctggcgaca ccatgctggg cgtgctgaaa ctggcgcaat gcgaagagaa agtgtttacc
    56341 actaccaatc tgaatttact gcgccagatt gccgaacgtg tggcaatcgc tgtcgataac
    56401 gccctcgcct atcaggaaat ccatcgtctg aaagaacggc tggttgatga aaacctcgcc
    56461 ctgaccgagc agctcaacaa tgttgatagt gaatttggcg agattattgg ccgcagcgaa
    56521 gccatgtaca gcgtgcttaa acaagttgaa atggtggcgc aaagtgacag taccgtgctg
    56581 atcctcggtg aaactggcac gggtaaagag ctgattgccc gtgcgatcca taatctcagt
    56641 gggcgtaata atcgccgcat ggtcaaaatg aactgcgcgg cgatgcctgc cggattgctg
    56701 gaaagcgatc tgtttggtca tgagcgtggg gcttttaccg gtgccagcgc ccagcgtatc
    56761 ggtcgttttg aactggcgga taaaagctcc ctgttcctcg acgaagtggg cgatatgcca
    56821 ctggagttac agccgaagtt gctgcgtgta ttgcaggaac aggagtttga acgtctcggc
    56881 agcaacaaaa tcattcagac ggacgtgcgt ctaatcgccg cgactaaccg cgatctgaaa
    56941 aaaatggtcg ccgaccgtga gttccgtagc gatctctatt accgcctgaa cgtattcccg
    57001 attcacctgc cgccactacg cgagcgtccg gaagatattc cgctgctggc gaaagccttt
    57061 accttcaaaa ttgcccgtcg tctggggcgc aatatcgaca gcattcctgc cgagacgctg
    57121 cgcaccttga gcaacatgga gtggccgggt aacgtacgcg aactggaaaa cgtcattgag
    57181 cgcgcggtat tgctaacacg cggtaacgtg ctgcagctgt cattgccaga tattgtttta
    57241 ccggaacctg aaacgccgcc tgccgcaacg gttgtcgccc aggagggcga agatgaatat
    57301 cagttgattg tgcgcgtgct gaaagaaacc aacggcgtgg ttgccgggcc taaaggcgct
    57361 gcgcaacgtc tggggctgaa acgcacgacc ctgctgtcac ggatgaagcg gctgggaatt
    57421 gataaatcgg cattgattta actgcaaatt gccggacaga tctgcctgtc cggcatacta
    57481 ttcatgaggt tttttcggac gatatttttc cggcagttct ggcaccggac gcttgtcatc
    57541 gatgagatga cgcacggtta agatcggatg acgccacagc attctcggcc cggcccaacg
    57601 cataatctgt ttcatctctt cacgctttgc aggctggtaa cagtgcaccg gacactgctt
    57661 acaggctggt ttctcttcgc cgaacacaca tttatccagc cgcttttgcg cgtaaacaaa
    57721 caacgcctcg taatgctccg gctccgctga cgcctgcggg catttcgctt gataaagatc
    57781 gatcattttt ttaatcgtca gtttttcacg agagatacgc ttgccggaca tgctgcctcc
    57841 acctcattaa gatgtattta tattacatct taatcttaaa gggcactatg actctaaaga
    57901 agaagggttc gccaaccgac gcaattttgc gtacttgctt cataagcatc acgcaaaagc
    57961 tgcaaaacag catctttccc ggaaccagca tcaagaactc gccgttcgct tcttcccctg
    58021 aaatgattaa ctccggtatc atgtgcgcct tatgtgatta caacgaaaat aaaaaccatc
    58081 acaccccatt taatatcagg gaaccggaca taaccccatg agtgcaatag aaaatttcga
    58141 cgcccatacg cccatgatgc agcagtatct caagctgaaa gcccagcatc ccgagatcct
    58201 gctgttttac cggatgggtg atttttatga actgttttat gacgacgcaa aacgcgcgtc
    58261 gcaactgctg gatatctcac tgaccaaacg cggcgcttca gcgggagagc cgatcccgat
    58321 ggcggggatc ccctaccatg cggtggaaaa ctacctcgcc aaactggtga atcagggcga
    58381 gtccgttgcc atctgcgaac aaattggcga tccggcgacc agcaaaggtc cggttgagcg
    58441 caaagttgtg cgtatcgtta cgccaggcac catcagcgat gaagccctgt tgcaggagcg
    58501 tcaggacaac ctgctggcgg ctatctggca ggacagcaaa ggtttcggct acgcgacgct
    58561 ggatatcagt tccgggcgtt ttcgcctgag cgaaccggct gaccgggaaa cgatggcggc
    58621 agaactgcaa cgcactaatc ctgcggaact gctgtatgca gaagattttg ctgaaatgtc
    58681 gttaattgaa ggccgtcgcg gcctgcgccg tcgcccgctg tgggagtttg aaatcgacac
    58741 cgcgcgccag cagttgaatc tgcaatttgg gacccgcgat ctggtcggtt ttggcgtcga
    58801 gaacgcgccg cgcggacttt gtgctgccgg ttgtctgttg cagtatgcga aagataccca
    58861 acgtacgact ctgccgcata ttcgttccat caccatggaa cgtgagcagg acagcatcat
    58921 tatggatgcc gcgacacgtc gtaacctgga aattactcag aacctggcgg gcggtgcgga
    58981 aaatacgctg gcttctgtgc tcgactgcac cgtcacgccg atgggtagtc gtatgctgaa
    59041 acgctggctg catatgccag tgcgcgatac ccgcgtgttg cttgagcgcc agcaaactat
    59101 tggcgcattg caggatttca ccgccgagtt gcagccggta ctgcgtcagg tcggcgacct
    59161 ggaacgtatt ctggcacgtc tggctttacg aactgctcgc ccacgcgatc tggcccgtat
    59221 gcgccacgct ttccagcaac tgccggagct gcgtgcgcag ttagaaactg tcgatagtgc
    59281 accggtacag gcgctacgcg agaagatggg cgagtttgcc gagctgcgcg atctgctgga
    59341 gcgagcaatc atcgacacac cgccggtgct ggtacgcgac ggtggtgtta tcgcatcggg
    59401 ctataacgaa gagctggatg agtggcgcgc gctggctgac ggcgcgaccg attatctgga
    59461 gcgtctggaa gtccgcgagc gtgaacgtac cggcctggac acgctgaaag ttggctttaa
    59521 tgcggtgcac ggctactaca ttcaaatcag ccgtgggcaa agccatctgg cacccatcaa
    59581 ctacatgcgt cgccagacgc tgaaaaacgc cgagcgctac atcattccag agctaaaaga
    59641 gtacgaagat aaagttctca cctcaaaagg caaagcactg gcactggaaa aacagcttta
    59701 tgaagagttg ttcgacctgc tgttgccgca tctggaagcg ttgcaacaga gcgcgagcgc
    59761 gctggcggaa ctcgacgtgc tggtgaacct ggcggaacgc gcctataccc tgaactacac
    59821 ctgcccgacc ttcattgata aaccgggcat tcgcattacc gaaggtcgcc atccggtagt
    59881 tgaacaagta ctgaatgagc catttatcgc caacccgctg aatctgtcgc cgcagcgccg
    59941 catgttgatc atcaccggtc cgaacatggg cggtaaaagt acctatatgc gccagaccgc
    60001 actgattgcg ctgatggcct acatcggcag ctatgtaccg gcacaaaaag tcgagattgg
    60061 acctatcgat cgcatcttta cccgcgtagg cgcggcagat gacctggcgt ccgggcgctc
    60121 aacctttatg gtggagatga ccgaaaccgc caatatttta cataacgcca ccgagtacag
    60181 tctggtattg atggatgaga tcgggcgtgg aacgtccact tacgatggtc tgtcgctggc
    60241 gtgggcgtgc gcagaaaatc tggcgaataa gattaaggca ttgacgctgt ttgctaccca
    60301 ctatttcgag ctgacccagt taccggagaa aatggaaggc gtcgctaacg tgcatctcga
    60361 tgcactggag cacggcgaca ccattgcctt tatgcacagc gtgcaggatg gcgcggcgag
    60421 caaaagctac ggcctggcgg ttgcagctct ggcaggcgtg ccaaaagagg ttattaagcg
    60481 cgcacggcaa aagctgcgtg agctggaaag catttcgccg aacgccgccg ctacgcaagt
    60541 ggatggtacg caaatgtctt tgctgtcagt accagaagaa acttcgcctg cggtcgaagc
    60601 tctggaaaat cttgatccgg attcactcac cccgcgtcag gcgcttgagt ggatttatcg
    60661 cttgaagagc ctggtgtaat aacaattccc gatagtcttt tgctatcggg aatattaacg
    60721 acaactgacg aataaaataa aaacaccctg tataatagga aagcttattt tacagggtaa
    60781 aaccatgcca tctacacgct atcaaaaaat caatgcccat cactatcgcc atatatgggt
    60841 cgttggtgat attcatggtg aatatcagtt attacaatcc cgcttacatc aactctcttt
    60901 tttccccgaa atcgacttac ttatttctgt cggcgataat attgatcgtg gaccggagag
    60961 tcttgacgtc ctgcgcctgc taaaccaacc ctggtttacg tcggttaaag gcaaccacga
    61021 agcgatggcg cttgaggcat tcgaaactgg cgatggcaat atgtggcttg ccagcggtgg
    61081 tgactggttt ttcgatttaa atgattcaga gcaacaagag gcaatagatc tgttgctgaa
    61141 attccatcac cttccacata ttattgaaat cactaacgac aacataaaat atgccatcgc
    61201 acatgcagat tatccgggga gtgaatatct ctttggtaaa gaaatagcgg agagcgaatt
    61261 actctggcct gttgatcgtg tgcagaaatc gcttaatggc gagttacaac aaataaacgg
    61321 cgctgattat tttatatttg gacatatgat gtttgataac attcagacgt tcgctaacca
    61381 gatttatatt gataccggat cgccgaacag cgggcggctg tcattttata aaataaagta
    61441 gtctcatgct tcttctgtga agcatgagta acccggtgtt attgcaggcc attattcatt
    61501 tttcgctacc agcaaagaga gatcctgctt caccagcgcg cgactggcac tctccggcaa
    61561 accgtcgtct gtaataatct gatcaaactc gcttaatggt aacgccagcc atgtcgccac
    61621 ctgaccatat ttcgtcgcat cacagaccaa aactcgctgg cggctggcac tggcaatcgc
    61681 ccgtttcacc gtgactttat cttccgctgg cgtagaaatc ccccgcacac tccatgacga
    61741 tgcagaaata aaagcctgat caatcatcag gctgcgcagc atggtcgcag cggcttcccc
    61801 gacacaggaa cggttttccc gacacactgc accgccagtg tgaataattg tgcaattact
    61861 gttgtcgagc aagtagtccg caataacgaa atcgtttgtg accacagtca gtgactccat
    61921 gtgaatcaga tgctgtgcta tcgctaacgt ggtcgttccc gcatccagat agatacaact
    61981 tcccggctga acaagacttg ccgccagctt gccaatagcc gctttttgcg tcattgccag
    62041 cgcagttttt acctgatgag aaggttcatg cgccacgcgt cccggagact ggacgcctcc
    62101 ggacaccagc acaacggctc cctgctgctc cagtttttgt aaatcccgac gaatggtcat
    62161 atgtgacaca ttcattctgt ccgttagttc agcaatactg acaatgcctt tttcagctac
    62221 catctcaagg atgatttggc gacgctctac gggtatcaac ttttgctcct tcctttgtcc
    62281 tgctgacatt ctacgctatt tgcctgcgaa acgtgcgcgg cgcaactaac gcttagttca
    62341 cataaaataa cacacaatgt taatttatgt gaatcagatc accatatcgt tatcttccag
    62401 cgcttatatt cacaatatca aacaaaatat cacttaaatt aacaaggaga gcagatgaaa
    62461 acgggatctg agtttcatgt cggtatcgtt ggcttagggt caatgggaat gggagcagca
    62521 ctgtcatgtg tccgcgcagg tctttctacc tggggcgcag acctgaacag caatgcctgc
    62581 gctacgttga aagaggcagg tgcttgcggg gtttctgata acgccgcgac gtttgccgaa
    62641 aaactggacg cactgctggt gctggtggtc aatgcggccc aggttaaaca ggtgctgttt
    62701 ggtgaaacag gcgttgcaca acatctgaaa cccggtacgg cagtaatggt ttcttccact
    62761 atcgctagtg ctgatgcgca agaaattgct accgctctgg ctggattcga tctggaaatg
    62821 ctggatgcgc cagtttctgg tggtgcagta aaagccgcta acggtgaaat gactgtcatg
    62881 gcctccggta gcgatattgc ctttgaacga ctggcacccg tgctggaagc cgttgccgga
    62941 aaagtttatc gcataggtgc agaaccggga ctaggttcga ccgtaaaaat tattcaccag
    63001 ttgttagcgg gcgtacatat tgctgccgga gccgaagcga tggcacttgc agcccgtgcg
    63061 gggatcccgc tggatgtgat gtatgacgtc gtgaccaatg ccgccggaaa ttcctggatg
    63121 ttcgaaaacc ggatgcgtca tgtggtggat ggcgattaca ccccgcattc agccgtcgat
    63181 atttttgtta aggatcttgg tctggttgcc gatacagcca aagccctgca cttcccgctg
    63241 ccattggcct caacagcatt gaatatgttc accagcgcca gtaacgcggg ttacggaaaa
    63301 gaagacgata gcgcagttat caagattttc tctggcatca ctctaccggg agcgaaatca
    63361 tgatcaagat tggcgttatc gccgatgatt ttaccggcgc gacggatatc gccagttttc
    63421 tggtggaaaa cggtctacca acggtacaaa ttaacggtgt tccaacaggt aaaatgccgg
    63481 aagcaatcga cgcactggtg atcagcctga aaacgcgctc ctgtccagtg gttgaagcca
    63541 cacagcaatc gctggcggct ctgagctggt tgcaacagca aggttgcaaa cagatctatt
    63601 tcaaatactg ctctactttc gacagtacgg cgaaaggtaa tattggcccg gttaccgatg
    63661 ccttaatgga tgctctcgac acgccgttta cggtcttctc tccggccctg ccggtcaacg
    63721 gacgtacggt ttatcagggg tatttgttcg taatgaatca actgctggcc gaatccggga
    63781 tgcgccatca cccggtaaat cccatgaccg acagctatct tccccgtctg gttgaagcgc
    63841 aatccacagg gcgctgcggc gtcgtttcgg cacatgtttt cgaacaaggt gtggatgccg
    63901 ttcgtcaaga gctggctcgc ttacagcaag agggctaccg ctacgcggtg cttgatgcgc
    63961 tgaccgaaca ccatctggaa attcagggag aagccttgcg cgatgcccca ctggtaacgg
    64021 gcggttctgg tctggcgatt ggcctggccc ggcagtgggc gcaagaaaac ggtaaccagg
    64081 ctcgcaaagc agggcgtccg ctcgctgggc gcggcgtagt gctctccggt tcatgctctc
    64141 aaatgaccaa ccgccaggta gcacattacc gtcaaattgc accagcccgt gaagttgatg
    64201 tggcacgctg cctctcaatt gaaactctgg ccgcttatgc acacgaactg gcagagtggg
    64261 ttctgggcca ggaaagtgta cttgctccac tggtttttgc caccgccagc actgacgcat
    64321 tggcagcaat tcaacagcaa tacggtgcac aaaaagccag tcaggcagta gaaacactgt
    64381 tttctcaact agcggcgcgg ttagcagcgg aaggcgtgac acgctttatt gtcgcaggcg
    64441 gtgagacctc cggcgtagtc acacagagcc tgggaataaa agggtttcat attggcccaa
    64501 ccatttcccc cggcgtgccg tgggtaaacg cactggataa gcctgtctca ctcgccctta
    64561 aatctggcaa cttcggtgat gacgcctttt tttcacgagc ccaaagagag tttttatcat
    64621 gagcgatttc gcaaaagtag agcagtcttt gcgagaggag atgacgcgga ttgccagttc
    64681 attctttcag cgcggctatg caaccggttc ggctggcaat ctgtcgctgc ttttacctga
    64741 cgggaattta ctggcgacac cgacaggttc atgcctgggc aatctcgatc cgcagcggct
    64801 ttccaaagtc gccgcggatg gcgaatggtt aagtggtgac aaaccctcga aagaggtgct
    64861 ctttcatctg gcgctgtatc gcaacaatcc gcgctgtaaa gcggtggtgc atttgcacag
    64921 cacatggtcg acggcgcttt cctgcctgca agggctggac agcagcaacg ttattcgtcc
    64981 gttcacacca tacgtggtga tgcggatggg aaatgtcccg ctggtgcctt attaccgacc
    65041 gggcgataaa cgcatcgcac aggatctggc ggaactggca gcagacaatc aggctttttt
    65101 actggcaaat catggcccag tggtttgcgg tgaaagcctg caagaagccg ccaacaatat
    65161 ggaagagctg gaggaaacgg caaagctgat ttttattctc ggtgaccgcc cgatccgtta
    65221 tctgaccgca ggtgaaattg cggaattaag gagttaatgc aatgcctcgt tttgcagcta
    65281 atttatccat gatgttcacc gaagtgcctt ttattgaacg cttcgccgca gcgcgaaaag
    65341 ccgggttcga tgctgtggaa tttctgtttc cctataacta ctccaccctg caaatccaaa
    65401 agcaactgga gcaaaaccat ctgacactgg cgctgttcaa taccgctccc ggagatatta
    65461 atgcggggga atggggatta tccgcccttc ccggacgtga gcacgaagca cacgcagaca
    65521 tcgacctggc actggaatat gcattggcgc tcaattgtga acaagtccat gtgatggcag
    65581 gcgtcgtgcc cgctggcgaa gatgctgaac ggtaccgggc agtatttatc gataatatcc
    65641 gctacgctgc cgaccgcttt gcgccacacg gcaagcgaat attagttgaa gcactcagcc
    65701 ccggcgttaa gcctcattat ctcttctcca gccagtatca ggcactggct attgttgaag
    65761 aggttgcgcg agataacgtg tttattcaac tagatacttt tcatgcgcaa aaagtagatg
    65821 gcaacctgac gcatttaatc cgcgactacg ccgggaaata tgcgcacgta caaattgccg
    65881 gactacctga tcgacatgaa ccggacgatg gagaaatcaa ctatccgtgg ctgttccgcc
    65941 tgttcgatga ggtgggatat cagggctgga tcggttgtga atataaacct cgtggcctca
    66001 ccgaagaagg gcttggctgg tttgacgcct ggcgctaatt cgttaaatcc ctaattacaa
    66061 cgtacccata catcccccca tctacggatg gggtaggtta actataactt tcagacaggg
    66121 tttcccatgt ccacaattac attgttatgc attgcgttag ctggcgtaat catgctgttg
    66181 ctgctggtca tcaaggcaaa ggtacaacca ttcgttgctt tgctcctcgt cagcctgtta
    66241 gtcgcacttg cggcaggtat accggcgggc gaagtgggta aagtgatgat cgccgggatg
    66301 ggcggtgtgc ttggttccgt cactattatt attggtctgg gcgctatgct ggggcgtatg
    66361 atcgaacact ctggtggtgc agagtcactg gctaattatt tcagtcgcaa gttaggtgac
    66421 aaacgaacta tcgctgcgct gactctggca gcgttcttcc tcggtattcc cgtcttcttt
    66481 gatgtcggct ttattattct tgcgccaatc atttacggtt ttgccaaggt tgccaaaata
    66541 tcgccactca aatttggcct gcctgtcgct gggatcatgc tcactgttca cgtggcggta
    66601 ccgccgcatc caggccctgt cgccgcagcg gggttactcc acgcagacat cggctggcta
    66661 accatcatcg gtattgcgat ttctattccc gtaggggttg ttggctactt tgcagcgaaa
    66721 ataatcaata agcgccaata tgcgatgtca gtagaagtac tggaacagat gcaactggct
    66781 ccggccagtg aggaaggcgc gacaaaatta agcgataaaa taaatccacc gggcgtcgcg
    66841 ctggtcacct cgctaattgt tattcctatc gcgattatca tggcgggtac ggtttccgca
    66901 acactgatgc cgccttcgca tcccctgctt ggtacgctac agctgatcgg ctcaccaatg
    66961 gtagctctaa tgattgcgct ggtgctggca ttctggttat tggctttacg tcgcggctgg
    67021 agcttacaac acaccagcga cattatgggc tcagcgcttc ctactgcggc ggtagtgatt
    67081 ttggttactg gtgctggagg ggtatttggc aaagtgctgg tggaatcggg cgtcggcaaa
    67141 gcccttgcca acatgctaca aatgattgac ctgcctctgt taccagccgc atttattatt
    67201 tcactggcgc tgcgtgcatc gcaggggtca gcaaccgtag caatactgac aaccggcggg
    67261 ttactctcag aagcggtgat gggattgaat ccgattcagt gcgtattggt gacgctggca
    67321 gcctgctttg gtgggcttgg tgcgtcacat attaatgact cagggttctg gattgtgacc
    67381 aaatatctgg ggttgtcggt agcagacggt ctgaaaacct ggacagtgtt aacgaccatt
    67441 ctcggtttta ccggattctt aattacctgg tgcgtatggg cggtaatttg accttaataa
    67501 aaaggtccga tgggcatcgg accttttatt gtgcacagaa aaggccagcc tcgcttgaga
    67561 ctggcctttc tgacagatgc ttacttactc gcggaacagc gcttcgatat tcagcccctg
    67621 cgtttgcagg atttcgcgca aacggcgcag gccttcaacc tgaatctggc gaacacgttc
    67681 acgggtgagg ccaatttcac gacctacatc ttccagtgtt gccgcttcgt accccagcaa
    67741 accgaatcga cgtgccagca cttcacgctg tttggcgttc agctcgaaca gccatttgac
    67801 gatgctctgc ttcatatcgt catcttgcgt ggtatcttcc ggaccgttct ctttttcatc
    67861 ggccaggatg tccagcaacg ctttttcgga atcaccaccc agcggggtgt ctaccgaggt
    67921 aatgcgctcg ttaagacgaa gcatacggct gacgtcatca actggcttat ccagttgctc
    67981 tgcgatctct tccgcacttg gttcatggtc cagcttatgg gacaactcac gtgcggttcg
    68041 caggtaaacg ttcagctcct ttacgatgtg aatcggcaaa cgaatagtac gggtttggtt
    68101 cataatcgcc cgttcaatcg tctggcgaat ccaccaggtt gcgtatgttg agaagcggaa
    68161 accacgttcc gggtcaaact tctctaccgc gcggatcagc cccaggttgc cctcttcgat
    68221 aaggtccagc aacgccagac cacgattgcc ataacggcgg gcaattttta ccaccagacg
    68281 caagttactc tcgatcatcc ggcggcgaga ggcgacatct ccacgcagtg cgcgacgcgc
    68341 aaaataaact tcttcttcgg ccgttaacag tggtgaataa ccaatctcac caaggtaaag
    68401 ctgagtcgcg tccaacacac gctgtgtggc tccctgcgat aacagttcct cttcggccaa
    68461 atcgttatca ctgggttcct cttctactaa ggccttttcg tcaaaaacct caactccgtt
    68521 ctcatcaaat tccgcatctt catttaaatc atgaactttc agcgtattct gactcataag
    68581 gtggctccta cccgtgatcc cttgacggaa cattcaagca aaagcctggt tccgccgatt
    68641 tatcgctgcg gcaaataacg cagcgggttt acggatttcc ccttgtaacg aatttcaaaa
    68701 tgcaagcgtg ttgaactggt tccggtgcta cccatggtcg ctattttttg ccccgcctta
    68761 acttcttgtt gttcccggac cagcattgtg tcgttatggg cgtaggcact caggtaatca
    68821 tcattatgtt tgatgataat cagattaccg tagccgcgca gcgcgttacc agcataaaca
    68881 acgcggccat ctgcggtcgc gataattgcc tgtcctttgc tgcctgcgat atcaatcccc
    68941 ttgttgcccc cctcagaagc gccaaaggtt tcgatcactt tgccctcagt cggccagcgc
    69001 caggtggaga taggcgtact ggttgatgta ctgctgacag tcggctcggt tgtgcttgct
    69061 gttggtaccg ttacaggcgc tgtgaccgtg gtcgcagttg gcttgttgtt cggcaacatt
    69121 ttgttagcac tctgttcacc cgaagactca gaatacgtaa ttgtcggttg cgacgcaaca
    69181 gcaacggtgg aattttgtgc aggcttgatc acaactcctt gctctgctgc gtcggcctgg
    69241 gtaatggcat ttccgccagt gattggcgta ccggaagcat tacccacctg caaggtctga
    69301 ccaacgttca gcgcgtatgg tgcctgaata ttgttgcgct gagcaaggtc acggaaatcg
    69361 ttgccagtaa tccaggcgat atagaaaagt gtgtcgcctt ttttcacggt ataggtactg
    69421 ccgctataac tgcctttcgg aatgttccca tactgacggt tatagacgat gcgtccgttt
    69481 tccatctgta ccggctgctg agctactggc tgcactggct ggatttgcgg ttgttgagta
    69541 gcctgaattt gtggctgctg caccggctga atttgcggtt gctgcgctgt agacgtcgtc
    69601 cccattttcg gcggcggcgt aatcaacata ccagaattag tatttgcagg cgcattgcca
    69661 ttaacggagc tgaccggtgc cggtggattt gaagtgtcag aacagcctgc cagccatagc
    69721 gaaaccagtg acaaagccgc aatgcggcga acggtgaatt ttgggcttcc cgcgctcatt
    69781 tatcccccag gaaaaattgg ttaataacca gtgacataat taccgtgcaa ggcaccctac
    69841 tgaacactgg aaaagatgtt cacgatacgc tgacctgcgg caaaataacc aggaaaaatc
    69901 caggtatttc ctcacgtttt aagccagctc acccttcact aaagggacaa agcgcacggc
    69961 ctccacggta tcgataataa attcgcctcc ccgacgacgc acccgtttca aatactggtg
    70021 ctcctcccct acgggtaaga cgagaatccc gccttcgtcc agctgcgtca ttagcgcagt
    70081 tggaatttcc ggcggtgccg ccgtaacaat gatagcgtca aacggcgcac gtgcctgcca
    70141 accttgccat ccatcgccat gacgggttga aacattatgt aaatcaagat ttttcaggcg
    70201 gcgacgtgcc tgccactgca agcctttaat ccgttcaacc gagcaaacat gctggacaag
    70261 atgcgccagg attgccgttt gatatcccga accggtgcca atttccagca cccgcgactg
    70321 cggcgtcagc tcgagtaatt cggtcattcg cgccaccata tatggctgcg aaattgtctg
    70381 cccctgacct atcggcaaag cgatattgtc ccaggctttt tgttcaaacg cttcatcaac
    70441 gaatttttca cgcggcacgg cggcaagtgc attcagcacc tgctcatcct gaataccttg
    70501 cgcacgtaat tgatccagaa gtgcttgtac gcgtctgctt accattgcgt gccaactccc
    70561 acgctgttta accagtctga aaccacatct tgcgcgctat gcgcagttaa atccacatgc
    70621 agcggcgtga tggagacata gccctcatct accgcagcaa aatcggtccc cggaccagca
    70681 tcacatttac cgcccggcgg gccaatccag tacagcgtat tgccgcgcgg atcttgctgc
    70741 gggatcacct gatctgccgg atgtcgtgta ccgcagcgcg tcacgcgaat acctttgatt
    70801 tgatccaagg gtaaatccgg aacgttaata ttaagaatac gcccggtgcg cagcggctct
    70861 ttacacagtg cgcgcaaaat tgaacaggtt accgccgcgg cagtgtcgta atgtttatgc
    70921 ccgtcaagcg agacggcaag cgccggaaaa cctaaatgac ggccttccat cgcggcggct
    70981 accgtaccgg aataaataac atcatccccc agattcggcc cggcgttaat tccggacaca
    71041 acaatgtccg ggcgcggacg catcagagca ttcacgccaa gatagacgca atcggtcggg
    71101 gttcccattt gcacagcaat atcaccattt tcaaaggtaa acgtgcgcag ggaggattcc
    71161 agtgtcagag aatttgaagc gccgctgcgg ttacgatcgg gggcgaccac ctgaacgtca
    71221 gcaaactcac gcaaggcttt cgccagcgtt tgtataccgg gtgcatgtac cccgtcatca
    71281 ttactcagca atatgcgcat aatcacctgt tgtgttgata agttccctga caacgctggt
    71341 tgcaaaacta cccgccggaa gccagaaacg gatctctacg gtgacgtcat cccaccaatt
    71401 ccagcttaat tgttgcggat acagcagcat cgctctgcgc gcggcttcaa ctttttcgcg
    71461 caccagtaaa gcttgtaatt cagtttctgc ggcgacagct gcttgttcga atgccagcgc
    71521 ttcacgctga gttccccatt cgccactgcc tggcaatgcg gcggttatca tcaactcttt
    71581 atcgttgacg cgacgctgta attccgccag ttcttcggtg gttgcgacaa accagctacc
    71641 acgtccggct aattgtagcg catcgccgtc aacaacttga ttaacgtctg cttttttgag
    71701 gcgctcagca acaatctgat taaacaacgc actgcgggct gccgacaacc aaaaactccg
    71761 tttattgcga tcgcgcaccg gagtattggt ttgcgcccag cgctgcgccc cctgcaagtt
    71821 gctaccgcca atcccaaaac gttgggcacc gaagtagttc ggtacacctt ttacgcaaat
    71881 atcgatcaga cgttgttcaa cgtcatcgcg attgctcact tcgcgcagaa ccagggtaaa
    71941 ggcgttacct ttcagcgcgc ctaaacgcag cttgcgcttg tgccgcgcat actccagcac
    72001 ctggcagcct tccagttgaa aggcgctcag atcgggcatt tccttgcccg gcacgcgagc
    72061 gcataaccac tgttccgtaa cagcatgttt gtctttttgc ccagcgaagc tgacttcacg
    72121 ggcatgaatt ttcaggaatt tcgccagtgc atccgccaca aaacgggtat tgcagccgtt
    72181 tttgaggatt ctaaccagaa tatgctcacc ttcaccatca ggctcaaagc ccaaatcttc
    72241 caccaccaca aagtcttccg gattggcttt cagcagcccg gtgccttgcg gtttaccgtg
    72301 gaggtaagtg agattatcaa actcaatcat tttgttgcct taatgagtag cgccaccgct
    72361 tcacaggcaa tcccttcccc acgtccggta aatcccagtt tttccgtagt agtggctttc
    72421 acgttaacat catccatatg gcagccgaga tcttcggcaa taaacacgcg catttgtgga
    72481 atgtgcggca acatcttcgg tgcctgagcg atgatagtga catcgacgtt gccaagggta
    72541 taacccttcg cctgaatacg acgccaggct tcgcgtagca gctcgcggct atcggcacct
    72601 ttaaatgccg gatcggtatc cgggaacagc ttgccgatat cccccagcgc cgccgcgcca
    72661 agcaatgcat cggtcaacgc atggagcgcc acgtcgccat cagaatgcgc cagcaatcct
    72721 ttttcgtaag gaatgcgtac gccaccaatg ataattgggc cttcaccgcc aaaggcatgt
    72781 acgtcaaaac cgtgtccaat tcgcattatg tattctcctg atggatggtt cgggtgaggt
    72841 aaaactcggc cagtgccaaa tcttccgggc gcgtgacttt aatgttatcc gcacggcctt
    72901 cgaccaactg aggatggaat ccgcaatatt ccagcgccga ggcttcgtcg gtaatagtcg
    72961 cgccttcatt tagagcgcgc gtcagacagt catgtaacag ctcacgaggg aaaaattgcg
    73021 gcgtcagcgc gtgccataag ccgttgcgat caacggtatg agcaatggca tttttgcccg
    73081 gttcggcacg tttcatagta tcgcgcactg gtgcggcgag gatccccccc gtgcggctgg
    73141 tttcgctcaa cgccaacaat cgcgcgaggt catcctgatg caaacaagga cgagcggcgt
    73201 catgcaccaa tacccactgc gcgtcgccag cggctttcag acctgccagc acggaatcgg
    73261 cacgctcatc accgccatct acaacggtga tttgcggatg attcgccaga ggaagttgtg
    73321 caaaacggct atcgccagga cttatggcaa tgacgacacg tttcacccgg ggatgcgcca
    73381 gcagcgcatg caccgagtgt tcaagaatgg tttgattacc gattgagaga tattgcttag
    73441 gacattccgt ttgcattcga cggccaaatc cggccgccgg aaccacggcg caaacatcca
    73501 aatgagtggt tgccatgtta attcccgggc tgatttatcg attgttttgc cccgcagact
    73561 gtgcgcgctt cgacgcgtca ggcaccagac gataaaaagt ttcgcccggc ctggtcatgc
    73621 tgagttcatt acgcgcacgc tcttcgagcg cctcctggcc gccattgaga tcgtcaattt
    73681 cggcaaaaag ttgatcgttt cgcgctttaa gtttcgcgtt tgtagcttgc tgtgccgcca
    73741 catcatcatt gacgcgggta tagtcatgta taccgttctt accgaaccac agcgaatact
    73801 gtagccagac cagaatagcc agcaacagca gcgttagttt acccatcctg ccccctgaaa
    73861 aacggcatca tcatcccatg catccgaaga cgactctaca tcctctgttg gggataccgc
    73921 gacaacgcgg gcaaatgtac cacatttgtc cattgttacg tatacccagg gcgtgcagaa
    73981 cataatctca ttattagtta cggtttgaat tatgaacaga ggagacggga aagtacaaat
    74041 tagcccagta gccacataaa cagtgcgcca aacataatgc ctactgtcac cagggtgaaa
    74101 acaatactgt agcgtagctt tccgtccatc aatgaatgca gcgcaatccc caccactacc
    74161 gcgacgggca tcagcgccag aaagaaaggc caggtgtaga taaagaagaa cagcgtgtta
    74221 gagccataaa tcaacatcgg catcgccagc gcaaataacc aggagataaa accgaccacg
    74281 gcaccaggca gtgaccatgt ggtttcttca tcctcagtaa ggctgtcgtt atttgttagt
    74341 gtaatgttat ggctattacg catatttgat cctgttactt tgacgaaccg ggcatggaaa
    74401 cccggtggtg tctcaggatc tgataatatc gttctgtctc aacagatcta ataattgctg
    74461 taccaaattt gttactaatt gttcaccatt gagatgaatt tctgccgatt caggcgcttc
    74521 gtaaacggaa tctattcccg taaagttgcg cagttcaccg gcacgcgctt tcttatataa
    74581 gcctttggga tcgcgggctt cgcaaatcgc cagcggcgta tcgacaaaca cttcgataaa
    74641 gcgcccttct cctacgcgtt cgcgaaccat ctggcgttcg gcgcggtgtg gcgagataaa
    74701 tgcggtcagc accaccagtc cggcttcaac catcaaattc gccacttcac cgacgcgacg
    74761 gatattctct ttacgatcgg catcgctaaa accgagatcg ctgcataatc cgtggcgaac
    74821 attgtcgcca tccagcagat acgtactgac gccgagttta tgtaacgcct cctccagcgc
    74881 cccggcgacc gttgatttac cggacccgga gaggccggta aaccacagca ctacaccacg
    74941 atgaccgtgg tgtagctcgc gttgttgcac agtgaccgga tggctatgcc agacgacgtt
    75001 ttcgtcatgc agcgccatta tttatccccc agcaaatcgc gcgcgcccca gtgcggaaag
    75061 tggcgacgaa ccagagcatt caattccagt tcgaatgcac tgaattcaga tggcgcagca
    75121 gttgcctggc taactggctc gtgcaccata ccggcaccca cggtcacatt gctcaggcga
    75181 tcgataaaaa tcagcccacc cgtcaccgga ttttgttgat aacgatctaa caccagcggc
    75241 tcgtcaaaag tgagatccac gaggccgatc ccattcagtg gcaggttttc aacttcacgc
    75301 tgggtaaggt tattaatatc aacctgatag cgaatgccat caacacgcgc gcgcgtcttc
    75361 ttaccggcaa ttttgatgtc gtaactctgc cctggagaaa gcggctgttc cgccatccat
    75421 accacatcca ccgacgcgct ctgcaccgcc ggtaacgctt cgtctgccgc cagcagcaga
    75481 tcgccacggc tgatgtcgat ctcatccgtc agcaccaggg tgatcgcttc tccggcaaag
    75541 gcttcttcgc gatcaccatc aaaagtcacg atccgcgcga cgtttgattc cacaccagag
    75601 ggcagcactt tgacacgttg cccgacttcc acgcgaccgg atgccagcgt tccggcgtaa
    75661 ccacgaaaat cgagattcgg gcgattaacg tactgcaccg ggaagcgcat tggctgagca
    75721 tccaccactc gctggatctc cacggtttcc agcacttcga gcagtgtcgg accgctgtac
    75781 cacggcatac tttcactttg cgatgccacg ttgtcgcctt ccagtgcaga gagcggcaca
    75841 aagcggatat ccagattacc cggcagctgc ccggcaaagg tcaaataatc ttcacgaata
    75901 cgggtgaacg tctcttcact gtaatccacc agatccattt tgttgatcgc cacgaccaga
    75961 tgtttgatcc ccaacagtgt ggagataaaa ctgtgacgac gggtttgatc gagcacgcct
    76021 ttacgggcat cgatcagtaa gatcgccagt tcacatgtcg atgcgccagt cgccatattg
    76081 cgggtgtact gctcgtgccc tggggtgtcg gcgataataa atttacgctt ctcggtagag
    76141 aaatagcggt aggccacgtc aatggtgatg ccctgttcgc gctcagcttg caggccgtcc
    76201 accagcagag ccagatccag cttttcgccc tgggtgccgt gacgcttact gtcgttatgc
    76261 agcgatgaga gctgatcttc gtagatttgg cgggtatcgt gcagcagacg accaatcaga
    76321 gtacttttgc cgtcatcgac gctaccacag gtcagaaaac gcagcaggct tttatgttgt
    76381 tgcgcaatca tccaggcttc gacgccgcct tcattggcga tttgttgtgc aagtgcggtg
    76441 ttcatcttaa aaatacccct gacgtttttt cagctccata gaccccgcct ggtcgcggtc
    76501 aatcacgcgg ccctgacgtt cactggtggt ggaaaccagc atctcttcga tgatttccgg
    76561 cagtgtttgt gcatttgact ccaccgcacc ggtcagcggc cagcagccca gcgtacggaa
    76621 acgcaccatc cgttttttaa tcacttcgcc cggttgcagg tcgatacggt tgtcatcaat
    76681 catcatcaac ataccgtcgc gttccagaac cggacgttcc gcagcgagat atagcggaac
    76741 aatgtcgata ttttccagcc agatgtattg ccagatatcc tgctcggtcc agttagagag
    76801 cgggaagacg cggatgcttt cgcctttgtt aatttgcccg ttgtagttgt gccacagctc
    76861 cgggcgctga tttttcggat cccagcgatg gaagcggtca cggaaagagt aaattcgctc
    76921 tttagcgcgg gatttctctt cgtcacggcg cgcaccaccg aaggcggcat caaaaccgta
    76981 tttgttcagc gcctgtttca ggccttcagt tttcataata tcggtatgtt tcgcgctgcc
    77041 gtgcacgaat ggattaatcc ccatcgccac gccttccggg tttttatgca ccagcagttc
    77101 gcagccgtag gctttagcag tacgatcgcg gaactcatac atctcgcgga atttccagcc
    77161 ggtatcgaca tgcagcaacg ggaaaggcag cgtacctgga taaaacgcct tgcgcgccag
    77221 atgcagcatg acgctggaat ctttaccgat agagtagagc atcaccggat ttgagaattc
    77281 tgccgccacc tcgcgaataa tgtggatgct ttccgcctcc agttgccgca ggtgagtaag
    77341 tcgtatttga tccataaccg ttcctttgca ataccgctat tttcttgcca tcagatgttt
    77401 cgactatagg gagcgtaaga gaacgaatga aattaccaat tagaatgagt agttccttaa
    77461 cggaataacg atttggcaaa gctaatatca aaaagtgctt aaggcaccgg atttcgggcg
    77521 tttaggaaga tttgaaattg ttttagcgca gcggcagttt catactatgg cggtaaaaaa
    77581 atttgcatgg tatttaagga ctcactatgt tttccgcatt gcgccaccgt accgctgccc
    77641 tagcgctcgg cgtatgcttt attctccccg tacacgcctc gtcacctaaa cctggcgatt
    77701 ttgctaatac ccaggcacga catattgcta ctttctttcc gggacgcatg accggaactc
    77761 cagcagaaat gttatctgcc gattatattc gccaacagtt tcagcaaatg ggttatcgca
    77821 gtgatattcg gacatttaat agtcggtata tttataccgc ccgcgataat cgcaagaact
    77881 ggcataacgt gacaggaagt acggtgattg ccgctcatga aggcaaagcg ccgcagcaga
    77941 tcatcattat ggcgcatctg gatacttacg ccccgctgag cgatgctgac gccgatgcca
    78001 atctcggcgg gctgacgtta caaggaatgg atgataacgc cgcaggttta ggtgtcatgc
    78061 tggaattggc agaacgcctg aaaaatacgc ctaccgagta tggtattcga tttgtggcga
    78121 ccagcggcga agaggaaggg aaattaggcg ctgagaattt actcaagcgg atgagtgaca
    78181 ccgaaaagaa aaatacgctg ctggtgatta atctcgataa cttaattgtt ggcgataaat
    78241 tgtatttcaa cagcggtgta aaaacccctg aagcagtaag gaaattaacg cgcgacaggg
    78301 cgctggcaat tgcgcgcagt cacggaatag ccgcaacgac caatccgggt ttgaataaaa
    78361 attatccgaa aggcactggg tgttgtaatg acgcagaaat attcgacaaa gcgggcattg
    78421 ctgtactttc ggtggaagcg actaactgga atcttgggaa taaggatggt tatcagcaac
    78481 gcgcaaaaac agccgcattc cctgcgggaa atagctggca tgacgtaaga ctggataatc
    78541 aacagcatat tgataaggca cttcctggaa gaatagaacg tcgctgccgt gacgttatgc
    78601 ggataatgct accgttggtg aaggagctgg cgaaggcgtc ttgatgggtt tgaaaatggg
    78661 agctgggagt tctaccgcag gggcggggga actccaagtg atatccatca tcgcatccag
    78721 tgcgcccggt ttatccccgc tgacgcgggg aacacacatg aatgtcggtt cagaccgtgt
    78781 ttttacccgg tttatccccg ctggcgcggg gaacactgag cgtcggcggc tcgctggatt
    78841 tgcgcggcgg tttatccccg ctggcgcggg gaacactttt gctgacaccg gcaatactga
    78901 acggctggcg gtttatcccc gctggcgcgg ggaacactcc tgcgcgtcag taaatacggc
    78961 agggcgtgtc ggtttatccc cgctggcgcg gggaacacag cgaccgaaat acaaatcaaa
    79021 atcagtataa cggtttatcc ccgctggcgc ggggaacaca ttcccccata attccccgca
    79081 caaaaaacag gcggtttatc cccgctggcg cggggaacac tacgtggaga atatttgcaa
    79141 cacccgcaag aacggtttat ccccgctggc gcggggaaca ctcactgagc ctcgccccta
    79201 tgtgatgcaa attcggttta tccccgctgg cgcggggaac acgccgccat gtcaggaaca
    79261 ccagagccgc ccgacggttt atccccgctg gcgcggggaa cacacgccgc cgccgttccg
    79321 gctggccgtc tcctgcggtt tatccccgct ggcgcgggga acactttcag cgcctccagc
    79381 actcgcaccg ccagcgcggt ttatccccgc tggcgcgggg aacaccagtg ctgtaaacga
    79441 ttgaaccagc tgatccaggg tttatccccg ctggcgcggg gaacacccgc gattcatcca
    79501 gcacggcaat ttaatgttcg gtttatcccc gctggcgcgg ggaacacact aagcatacat
    79561 aactgttttt aaacaaattt attccgcatc aacaatctac caactaaatt aaaacatttc
    79621 cttattttta aagaacggat aacttattga ttatcaacag gaagaaaaga aaccaaacgc
    79681 aacccatcca aatccaccgg aatacgtcta ttttcacccc aggtctgaaa ttcaaaacct
    79741 gactcggtat tggtcgccca agccatcact acatttccgc aacctgccag ttgagagatt
    79801 tgctgccaga tcatctcccg aatacgtttg gatgtatctc cgacatacac accggcacgc
    79861 acttccagta gccagatagc gagccgtcca cgtaaacgtg gaggaacatt ttccgttaca
    79921 actacgatca tactcatccg ccgcgtcctc gatgaccgct atcgcctaag gtttcaggtt
    79981 cagggatggc aggcggtaac atatccggcg cgggttgtgg tggttcaatt tcaccagcgg
    80041 caagcacttc ctcaattaac ggaattaact tgcccgttaa tttactacta cggaaaatat
    80101 cgcgacaggc caacctgact tctttatctg gttctgcggg ttgcctcgct gctatttcaa
    80161 atgcctttgg cacaaccaaa tcaaatttaa tgatatcggc tatgtcataa acaaatgaaa
    80221 gcggtttgcc gctatggata aaaccaatag cgggcgcata tcccgcagct aatactgcag
    80281 cttcagaaat accgtacagg catgatgtgg cagcactgat gcaacgattg acaacatcgc
    80341 ctttttccca gtctttagga tcgtatttgc gaccattcca tttcacacca tattgtttcg
    80401 ccagtaatgc atacgtctgg cgaacgcggg atccctcaat tccccgtaac tgctctactg
    80461 aacggcgagc tggcggtggc tcacgaaaac gtaattcata cattttgcgc accaccttca
    80521 ggcgtagatc ttccgttaaa gccagctttg cctggtagag taacttatca gcacgcgccc
    80581 caccgggttg tccggaagag tagacgcgaa cacccgcttc accgacccag accagtagcg
    80641 tccccaccgt ggcggccaga tgcaccgccg cgtgggaaac tctcgttccc ggttcgagca
    80701 taatgcaggc gaccgatccc accggaatgt gcgtgcggat cccggttttg tcgatcagca
    80761 cgaaagcgcc gtccagtacg tcgatttgac cgtactggag gaagatcatg gaggtgcgat
    80821 cttttaacgg gatcgggctc agcggtacaa acgtcacgcc tctgctccag gtttgatcag
    80881 catcagacca caaccgaacg cccggctttt gccatacccc tgactgagac gttgcagaaa
    80941 taacccagga tcggtgaccg taagcatccc cgtataatcc acactactga actggatcag
    81001 ttgccaggag ttttcccgcc ggagttgttg ttgtcggtag gcatcaaccg aggtatccag
    81061 tagtgtaaaa ccacttcttt ccccctgcgc tgccagccag tccagcgccg cctgttgttg
    81121 atgcaaccag acatcacttc cttccgcctg tcccctcacc tgccgtttcg cctccatcag
    81181 cagatcgtgg cgcttgcccg ctttacagat tgttggattc gcccgcaggt tgaaacaaag
    81241 ttgttgtccg gtactcagct cgggcgtaaa tgaccggcat tcgatggtga aagtttcact
    81301 ttccgccggg cgttcctgcg agaggacaaa aaagcgaaac gcgccctgga gttcttcccg
    81361 acgataaaga aattgccttt ctttgccgcc agggaagaga tcccacaacc actgatgcat
    81421 cacatattca ccgcgatcca ccagatgcag caactgcgca ggcgaaagct ggccggtatg
    81481 taaggttatt cttgagaggt acatggttcc tccttgctga gccacggccc ctgattgatg
    81541 gtgcgttccc caaacagcca ctgctgacga tttaaaggaa catcccggcg gcgtaatatt
    81601 ttgcttgcga ccaaaccatc gtgctcccct tcccaccagc attcatcctg aagtttcggg
    81661 agtgagactt tcagttcgcg gaaacgatcc tgatactgtt ggtatgcgtt acgtaagaca
    81721 tcagacgcgt tgccttcgag cagtaacggc gcaagtggta acgccagcgg atgacttttt
    81781 cgccccagat aaagcggaaa aaccggatgg cgtaaaccgt cctgcaactg ttcgaggctg
    81841 taaggcgcat cgggggttgt tgccaccgcc accatccacc aggcatcggt gtagtagtcg
    81901 cgccgggaga taatcgcgct caaaagctca gggtcgctca actcttcgcg acggctgaaa
    81961 taacgtgctt tacgcacctc ttttggcatc tggaccgtgt gataatcccg tgcccagcgc
    82021 gggttacggc tggcgcaaac caccagtgaa tagtggcgat taaacgcgtt taagcgttcg
    82081 gtatcatcac gccgaatccc taccccggca gccagtagcc ccagcaatgc tgagcgcgaa
    82141 ggaagttcat gggtatgacg aacttcacct ggagcatcga caccccagga cgccatcggc
    82201 ccatgaagct gaaaaatcag atattggctc ataagccgcc ccttacgcgc agataaagtc
    82261 cagcacgtcc ttcatgcttc cctgtttgtt catcacgtca aaacttgcgt aatcggtctt
    82321 ctgttcgtag accgtattca tattttcgcg aagagttgta atacgctgca ccgccacctc
    82381 taactgacgg gtgccattaa tgggttcata gaaagctgcc gccagagaac gcggttgatc
    82441 ggtgcctttt tctgccagcg cccaggaggc gtaggcacgg ctggcaaagc tgttctgttt
    82501 gccggttggg gagactttaa gtgcggcttc cgtaaaggca cgtatggtct gattagctaa
    82561 cgcttcgtca ccgccaaggt tttcgaccag cagatcttta tcaatgcaga tataggtgta
    82621 gaacagtgca gaaccgaatc cggtttcacc aagatgcccg gcaccggcat cttcagaagc
    82681 ctggcgcaaa tcatcaacgg cggtgaaaaa atcatcttcg acaatcgttt cactgacacc
    82741 aaatgcgtgc gctacctggc aggcggcttc aacattaaac tcgggtttat tcgccagcat
    82801 acgaccaaac atggcaatat ctaccgccat acggtctttg cgtaacaacg cgagatcttc
    82861 ctcttttggc gcgcgctttt cttctgcaag ctgatgggcc agcactttta cggcgtcaaa
    82921 ttctgccggg ctgatatgga ctaactgttc agtttcggcg ttagtgagcg gatcttttgg
    82981 ttttttgtcg tttttagctt tcccaagata atctgcaatt tttgccgccc attcgatggc
    83041 ttttttctct tcgattcctt tctcaatcag gatagttgcc gcctcacgcg caatacgccc
    83101 actgcgaata ccaatatggc ccgccagtgc ctgttcaaaa agtgcagaag tgcgccacgc
    83161 acgtttcaga ctttgcgagg aaacgcgcag acgcgttgct ccacccagca ccacagtttt
    83221 tggcgcaccg gtatcatcac ggttaaggtt ggcagcaggg taagcggtta acaaatgaag
    83281 ctgaataaat gttgtcatga gatagtcctt tattgatttt gttcgttatc ggcgtcgcca
    83341 gcctggtaat attccagcgc ccagcggata cggataaatt cggttggccg ctgctggcgg
    83401 cggtgatgat tgagcaggtc gtcgctctcc tggcaccaac ggaagacccc ctctgccaga
    83461 gagtcaagat tgacggaacc gtttaataat ctgactgcgc ggcgtaactg gcgcagtaat
    83521 tcatccggtg tttttactgc cgacagacga gtaaaacgcc cctttgacat taccgccgcc
    83581 agctgcgcgg caaaaggctg ccgttcatca atagctttaa cattggcgct aactgcggct
    83641 atcagcgcca gtgcggtgat acgccactca ggttcatcct gccactttat ttgtctgttc
    83701 ttcagaaaca ggcgaaatcc atccgtcaga caaacatcat taaccgtcgt actacgccgc
    83761 agactggcac gttcgccacg tttctcctgc aattcctcgt gccatttgcg cagcgtggct
    83821 ttgtgctcct cttttacaat actcattcag cagcctcctg ctttttctcc ctggcggctt
    83881 tagcactttg cttctccgcc gatgttgtaa aatatttctt gcgcgcggtc atgacgcgtt
    83941 ccagatcaac gggctcataa ggattggtga atacacgctc gtcaaaatcc tgacgtgcga
    84001 ataaccaaat ttccttattc catttgctga gtaattcatc cgcatcctga ccttcttcaa
    84061 tttggcgcac taacctcaga aagcgatgct gagttttgtt ccagaagtcg atatccacaa
    84121 aactaaaatc accccttgca ccttttggat cggagaacca tgcttctttc aatgcactcc
    84181 gtaacagact tagaatccgt gaagctgttt gcgcagccag ccgcagcttc ggtatctgac
    84241 cttctttttt atcgagcagc agcgggaaat ggtgttcgta ccaacagcgc gctttcatgt
    84301 tgtcgaaatc atagccaaat ccccacaggc ccacttttgc ctgcttgaga ctgctggcat
    84361 tgaagagttt caccaccagc gcgggaagtt ccgtattgtt ttctgattta cccgtttcga
    84421 taaggcctaa ccagtcacgc cagattaaac cgcccggttg tggtttaacg gagtaaaact
    84481 cgccaccctc tttaagtggt acacggtaag gcgttaaggg atgctgccac atggcataat
    84541 tcgcaccgta atttttggtc gtcatcaggc tcaggagcgc gtcgctctgc tcaccgcaaa
    84601 tatcgcagtt gccgactgtc gtggtattaa aatcaatacg aatacggcga ggcattcccc
    84661 agtacgcctg gagtttattg acctgctcat cggttaccac cgcaccggcc agttcgctgg
    84721 tgcgcgtcgg gccaagccag gggaaaacca gatcgtcaaa ttttttgggt agcggtaaat
    84781 cggcttcatc ctgcggcatg acattgatcc acagtttgcg ccacaaggga gtttgttgat
    84841 taccctgata ttcctgtaat tcaatcagag tggtcatcgg cccaccgccg cgtaaaccgg
    84901 tgcggtagcc tttgccacct gacggcgcat tcaactgtag ggagaacaga gctaacgcag
    84961 aacaatgtgg gcacaggtat tccgttacac cacgcttgat aaagtggtct ttattaaact
    85021 tcgttgtttg agcgccggga atctcaggca gtagcgaagc gaccggaact ttatctccgg
    85081 tgagcgcctc gaaatcctgc ataaatgaag gggaatctgg cccaaactgg aaagcatgtt
    85141 ctaatgactg caatgcttcc cgtagctttt cagcttccag tccgtcttcc cagatatcat
    85201 cccaacgacg atgatctttt ggcgcgaagc tggtttgtag tagccccagc aaaaactgcc
    85261 ataccgcacc ctggagatct gcccgcggcg cagaaatatc gacaacattt tcatccgcca
    85321 gatcgactgg cgccagtttg cctgtcgttc cgtctttaaa acgaacgggc aaccacgggg
    85381 ttgtcagaag tgaaaacgag ttcatacgca tcctctcgta aaaaagacca tcccaggtcg
    85441 gttgtccatc tttccatcct tttcggtgta tcaactattc agagagtcct gtcgcagaca
    85501 tctcaaccaa ccttgccaat caatccttcc gtagccgaat acccgcaact ttcgtcatcg
    85561 ttgactaaaa tcacgtttgc catctccgga tcttgtcgct gttcaatgca ccacagcctg
    85621 aacgcctctc cctccagtaa agaaaactca tcccgatgtt ttttccacca gcttcggcgc
    85681 actctgacaa cgctcatttc ccatgcgtga gcaccggtgg cataaggctt caccacaccg
    85741 tcaatacagg tagccagcca cagggaaaca gactcctcag ccagacgtgt cgacagtttt
    85801 tccgggaggt aatcgttgat attggcggca tagccgggcc tgaagttcag cacaaacttt
    85861 ttagccattg cgcgatcaca gtaatatttg cccacttgct cctgctcgct gcgggcaaat
    85921 ccttccggca ttaccacgtc ctcaccgtag acggattcaa taagaagccg ggctgcgtgt
    85981 ggcatctgaa tagcaccttg ctcacgcagc acacgctgcg tcagccagat tcgcccatga
    86041 tcgggataga caaatgcact gttacgcatg gcactgccaa accattcgtc gccaggagag
    86101 tcgtcccaga cgggagccag aatcagcaat ttaggggggg aacgctcgtc ctttccgtca
    86161 cgctttaact gaccattaat atcgcggata tgccgctgta atcgtcctgc tcgctgaatc
    86221 agcaaatcaa caggggccag gtcggagatc atttcgtcca ggtcaatatc cacgctttgc
    86281 tcaattactt gtgtacaaac aatgacttgc gacgatctct gtaaactaca atatttacca
    86341 aagcgtgcca gcgtttccgt ttcaattcgc tggcgatcgc taaaagcaaa gcggctatga
    86401 aaaagtgaaa ggctggaagc aggaatgacg ccgcgggcaa gcagctgacg atgaacctta
    86461 atagcgtcat cgacagaatt ccggatccag gcgatgcatt tcccctgact taccgccgat
    86521 tcgatacgcg caatacactc ttgttcacta tgaagccaac ccacgctgac gctacgctca
    86581 acgtctttgc gcgtcgctac ccggtgtgag ttcacatcgg atttcgtgac atgcgtcagc
    86641 caggggtaat catccttttc caggaacgga gcttcttgct ggccctctgt accccgcgca
    86701 aaggcagcga cgagtttgtc gcgctgctgt tgagataacg tggcagaaag caaaataacg
    86761 ctgtttccgc cacgcgcctg ccgctcgatc aacccttcaa gaatgcacga catgtaagcg
    86821 tcacaggcgt ggatctcatc agccagcagg attttgttac tcagccccag aagccgcaga
    86881 ttattatgtt tgaacggcat caccgccatc atcgcctgat ccagcgtgcc gacgccaatt
    86941 tcagccagca acgccttctt gttactgtcg gcaaaccagg ccgcacatcc ctgactgaac
    87001 gtttgttcat ccggttcttc tgacccgact aaatcaccag accagagtga ttcattaaag
    87061 cggtccatta atgtgcgggc actatgtgcc agcaccaggc tggggcggga ttctggcgaa
    87121 tagaaagcaa gccaggtttt gaccagccga tcgtacatgg cattggccgt tgccattgtt
    87181 ggcagaccaa aaaacagccc ctgagctttc cccgcagcta tcaacctgtg cgccaggata
    87241 agcgccgctt ctgttttacc tgcgccagtc acatcttcca gaataaataa ctgcggtcct
    87301 tgctggctga tatccagatc cagcaccttt tgctgtaacg gtgtcggatt ctcaataaaa
    87361 ggaaacagcg tattaattcc gttgaaaggc gcgacttttg cttttagagg aaagacggtt
    87421 aaggcgtttt gagcctgaat taaagttttc tgccagtaac ctttaatatc cattgggtgt
    87481 gcgacgcgtg gaaaaaatcg cgttgacgaa cccgtccagt ctgcgagcac gacggttgca
    87541 gagatatacc aggaaaggtg ttttataagt tcaatgccct catcatcatc ccagaatgcg
    87601 gggatctcta tgagcggaaa cagtggtttg atttcaagga gaaaatctcg tgctgcagct
    87661 ttgtcttcag gcagaaaatt atccaattca tccatacgat cagggggccg accatgatgc
    87721 cctgtcgtca cgggcatcca catttctatc actcgcctaa gtttgcgcgg agagagcgaa
    87781 gatgaaggaa gtaactcctg acattcactt aaataatgat tccacaacca gtagcccagc
    87841 gttgaatgag agattttttc gtaatttttt ctggcacctt cctgaatctt gagttcaggg
    87901 ggcaggtaaa gttgttgaaa agagcgggca aattttccaa tatcgtgcca gcacagcaac
    87961 caggcgaaaa attgagccgc ctgttccttg tcagaaatcc ctaattgacg aaaataatca
    88021 gccagcccga agcaatttct tttaaccatt aaatagccca tcgcggctac atccagcgaa
    88081 tgccagcaaa gaaggtgata gtcgtcgccc ccgtctttct cgccgcgtcg ggtttttccc
    88141 cagaaatcaa aaaaagtcac aatattttta
//
LOCUS       DAPHKZ010000002        82416 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.002, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000002 DAPHKZ010000000
VERSION     DAPHKZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 82416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82416
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.002"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..852
                     /locus_tag="RH288_000093"
     CDS             <1..852
                     /locus_tag="RH288_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
                     /protein_id="HDV4029200.1"
                     /translation="FTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESI
                     FNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIVVAWSDRTVRIQV
                     GYGLEEKVTDALAGDIIRSNMIPAFKQQKLAKGLELAINALNNQLTSQHQYPTNPSES
                     ESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVCISAIYLLDLFLFSDKI
                     FSIAVFSFFFTFTIFMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSGGGGSSGG
                     GGASGRW"
     gene            complement(912..2210)
                     /gene="eno"
                     /locus_tag="RH288_000094"
     CDS             complement(912..2210)
                     /gene="eno"
                     /locus_tag="RH288_000094"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDV4029201.1"
                     /translation="MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEN
                     KSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(2298..3935)
                     /gene="pyrG"
                     /locus_tag="RH288_000095"
     CDS             complement(2298..3935)
                     /gene="pyrG"
                     /locus_tag="RH288_000095"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HDV4029202.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQM
                     AVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVE
                     TRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARH
                     VANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVD
                     DSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK"
     gene            complement(4163..4954)
                     /gene="mazG"
                     /locus_tag="RH288_000096"
     CDS             complement(4163..4954)
                     /gene="mazG"
                     /locus_tag="RH288_000096"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDV4029203.1"
                     /translation="MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVL
                     DAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFAD
                     SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWT
                     TLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQK
                     ANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL"
     gene            complement(5025..5360)
                     /gene="mazF"
                     /locus_tag="RH288_000097"
     CDS             complement(5025..5360)
                     /gene="mazF"
                     /locus_tag="RH288_000097"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="HDV4029204.1"
                     /translation="MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPVVVLSPFMYNNKTG
                     MCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLI
                     KAKINVLIG"
     gene            complement(5360..5608)
                     /gene="mazE"
                     /locus_tag="RH288_000098"
     CDS             complement(5360..5608)
                     /gene="mazE"
                     /locus_tag="RH288_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MazE"
                     /protein_id="HDV4029205.1"
                     /translation="MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLII
                     EPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW"
     gene            complement(5686..7920)
                     /locus_tag="RH288_000099"
     CDS             complement(5686..7920)
                     /locus_tag="RH288_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDV4029206.1"
                     /translation="MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQ
                     QTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     VVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRD
                     ITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGS"
     gene            complement(7968..9269)
                     /gene="rlmD"
                     /locus_tag="RH288_000100"
     CDS             complement(7968..9269)
                     /gene="rlmD"
                     /locus_tag="RH288_000100"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDV4029207.1"
                     /translation="MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGL
                     LPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQR
                     SKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
                     QCPILAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREK
                     LERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVA
                     RALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQ
                     NVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPA
                     TLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK"
     gene            9326..12082
                     /gene="barA"
                     /locus_tag="RH288_000101"
     CDS             9326..12082
                     /gene="barA"
                     /locus_tag="RH288_000101"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HDV4029208.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFH
                     LDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTL
                     NIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR
                     GSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYS
                     PTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKL
                     KQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKL
                     IGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPE
                     VNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGL
                     VDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREAS
                     KILG"
     gene            complement(12314..13654)
                     /gene="gudD"
                     /locus_tag="RH288_000102"
     CDS             complement(12314..13654)
                     /gene="gudD"
                     /locus_tag="RH288_000102"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HDV4029209.1"
                     /translation="MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKAT
                     PLPYQSQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQV
                     PEKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            complement(13675..15015)
                     /locus_tag="RH288_000103"
     CDS             complement(13675..15015)
                     /locus_tag="RH288_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase-related protein"
                     /protein_id="HDV4029210.1"
                     /translation="MATQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHTGIGEAPGGDVIYQTLVDAIPMVLGQEVARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLLGKALNVPVCELLGPGKQREAITVLGYLFYIGDRTKTD
                     LPYVENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTQNPLEIKNGKIAVP
                     DAPGLGVELDWEQVQKAHEAYKRLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            complement(15017..16369)
                     /gene="gudP"
                     /locus_tag="RH288_000104"
     CDS             complement(15017..16369)
                     /gene="gudP"
                     /locus_tag="RH288_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HDV4029211.1"
                     /translation="MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNKKELEYI
                     AAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGM
                     LLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
                     "
     gene            complement(16804..17253)
                     /locus_tag="RH288_000105"
     CDS             complement(16804..17253)
                     /locus_tag="RH288_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDV4029212.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDW
                     LPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDSLGFQPNLRYGVIALGDSSYVNFCN
                     GGKQFDALLQEQSAQRVGEMLLIDASENPEPETESNPWVEQWGTLLS"
     gene            complement(17271..18053)
                     /gene="truC"
                     /locus_tag="RH288_000106"
     CDS             complement(17271..18053)
                     /gene="truC"
                     /locus_tag="RH288_000106"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HDV4029213.1"
                     /translation="MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDY
                     PLVEELDKIADKFAREDKGPQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLT
                     IHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS"
     gene            complement(18053..18382)
                     /locus_tag="RH288_000107"
     CDS             complement(18053..18382)
                     /locus_tag="RH288_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HDV4029214.1"
                     /translation="MTTHDRVRLQLQALEALLREHQHWRNDEPQPHQFNSTQPFFMDT
                     MEPLEWLQWVLIPRMHDLLDNKQPLPGAFAVAPYYEMALATDHPQRALILAELEKLDA
                     LFADDAS"
     gene            complement(19004..19549)
                     /gene="syd"
                     /locus_tag="RH288_000108"
     CDS             complement(19004..19549)
                     /gene="syd"
                     /locus_tag="RH288_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HDV4029215.1"
                     /translation="MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIIST
                     TEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQ
                     TWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
                     RKRTHLASNLAEFLNQLKPLL"
     gene            19617..20465
                     /gene="queF"
                     /locus_tag="RH288_000109"
     CDS             19617..20465
                     /gene="queF"
                     /locus_tag="RH288_000109"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HDV4029216.1"
                     /translation="MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGL
                     KADNLPFHGTDIWTLYELSWLNAKGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQ
                     TRFNNWDEVRQTLERDLSTCAQGKISVALYRLDELEGQPIGHFNGTCIDDQDITIDNY
                     EFTTDYLENATCGEKVVEETLVSHLLKSNCLITHQPDWGSLQIQYRGRQIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPST
                     TRLVRQ"
     gene            20577..21941
                     /gene="ppnN"
                     /locus_tag="RH288_000110"
                     /gene_synonym="ygdH"
     CDS             20577..21941
                     /gene="ppnN"
                     /locus_tag="RH288_000110"
                     /gene_synonym="ygdH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HDV4029217.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLR
                     DILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMP
                     LVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAF
                     SGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICT"
     gene            22498..23787
                     /gene="sdaC"
                     /locus_tag="RH288_000111"
     CDS             22498..23787
                     /gene="sdaC"
                     /locus_tag="RH288_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HDV4029218.1"
                     /translation="METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGDMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPVIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS"
     gene            23845..25212
                     /gene="sdaB"
                     /locus_tag="RH288_000112"
     CDS             23845..25212
                     /gene="sdaB"
                     /locus_tag="RH288_000112"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HDV4029219.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPSFIQDVNTHGRLMLANGQ
                     HEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
                     DSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRG
                     GIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVACD"
     gene            25324..26079
                     /gene="xni"
                     /locus_tag="RH288_000113"
     CDS             25324..26079
                     /gene="xni"
                     /locus_tag="RH288_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HDV4029220.1"
                     /translation="MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTH
                     AVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNE
                     ADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
                     QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(26134..27282)
                     /gene="fucO"
                     /locus_tag="RH288_000114"
     CDS             complement(26134..27282)
                     /gene="fucO"
                     /locus_tag="RH288_000114"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HDV4029221.1"
                     /translation="MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQC
                     GVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIGGGSPQDT
                     CKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHI
                     KAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVG
                     IPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW"
     gene            complement(27310..27957)
                     /gene="fucA"
                     /locus_tag="RH288_000115"
     CDS             complement(27310..27957)
                     /gene="fucA"
                     /locus_tag="RH288_000115"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HDV4029222.1"
                     /translation="MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTG
                     IPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVS
                     ILNRSIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIAC
                     EVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE"
     gene            28504..29820
                     /gene="fucP"
                     /locus_tag="RH288_000116"
     CDS             28504..29820
                     /gene="fucP"
                     /locus_tag="RH288_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HDV4029223.1"
                     /translation="MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYA
                     LGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAI
                     VLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALI
                     AMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN"
     gene            29853..31628
                     /gene="fucI"
                     /locus_tag="RH288_000117"
     CDS             29853..31628
                     /gene="fucI"
                     /locus_tag="RH288_000117"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HDV4029224.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEK
                     LRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPT
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQG
                     NSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVV
                     ATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLIN
                     SGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRL
                     TGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSA
                     WAAHGMDIEGQDYRACQNYGPLYKR"
     gene            31737..33155
                     /gene="fucK"
                     /locus_tag="RH288_000118"
     CDS             31737..33155
                     /gene="fucK"
                     /locus_tag="RH288_000118"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HDV4029225.1"
                     /translation="MKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENN
                     TWHQWSLDAILQRFADCCRQINSELTECHIRGIAVTTFGVDGALVDKQGNLLYPIISW
                     KCPRTAAVMDNIERLISAQRLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFI
                     SSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIG
                     TLQNSAAAMLGLPVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDT
                     SLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAP
                     GADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKA
                     SELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEAR
                     AQIHYQYRYFYPQTEPEFIEEV"
     gene            33157..33579
                     /gene="fucU"
                     /locus_tag="RH288_000119"
     CDS             33157..33579
                     /gene="fucU"
                     /locus_tag="RH288_000119"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HDV4029226.1"
                     /translation="MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIR
                     ADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPSPDI
                     IRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP"
     gene            33637..34368
                     /gene="fucR"
                     /locus_tag="RH288_000120"
     CDS             33637..34368
                     /gene="fucR"
                     /locus_tag="RH288_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HDV4029227.1"
                     /translation="MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQT
                     QGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDAS
                     STCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
                     LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEA
                     RIGHLDEVTHIISDERQVATSLVTA"
     gene            complement(34412..35512)
                     /gene="rlmM"
                     /locus_tag="RH288_000121"
     CDS             complement(34412..35512)
                     /gene="rlmM"
                     /locus_tag="RH288_000121"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HDV4029228.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIY
                     ECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
                     GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVC
                     DMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINA
                     QIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
     gene            complement(35505..35900)
                     /locus_tag="RH288_000122"
     CDS             complement(35505..35900)
                     /locus_tag="RH288_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HDV4029229.1"
                     /translation="MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGL
                     EYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVT
                     PVGGVSFLAGWALMLVGAIRLKRKGVSHE"
     gene            complement(35919..36836)
                     /gene="gcvA"
                     /locus_tag="RH288_000123"
     CDS             complement(35919..36836)
                     /gene="gcvA"
                     /locus_tag="RH288_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HDV4029230.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLP
                     SFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAAAEQEKFRFRYEQ"
     gene            complement(37187..37414)
                     /locus_tag="RH288_000124"
     CDS             complement(37187..37414)
                     /locus_tag="RH288_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HDV4029231.1"
                     /translation="MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVELDQ"
     gene            37606..38811
                     /gene="csdA"
                     /locus_tag="RH288_000125"
     CDS             37606..38811
                     /gene="csdA"
                     /locus_tag="RH288_000125"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HDV4029232.1"
                     /translation="MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEATQQFYS
                     LSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTTESINMVAQCYA
                     RPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPELITPR
                     SRILALGQMSNVTGGCPDLARAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAF
                     SGHKLYGPTGIGVLYGKSELLEAMSPWLGGGKMVHEVSFDGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLADYDINQAESWSRSLATLAEDALAKRPGFRSFRCQDSSLLAFDFA
                     GVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAV
                     DRALELLVD"
     gene            38811..39254
                     /gene="csdE"
                     /locus_tag="RH288_000126"
     CDS             38811..39254
                     /gene="csdE"
                     /locus_tag="RH288_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HDV4029233.1"
                     /translation="MTNPQFAGHPFGTTVTAETLRNTFAPLTQWEDKYRQLIMLGKQL
                     PALPDELKAQAKEIAGCENRVWLGYTVAENGKMHFFGDSEGRIVRGLLAVLLTAVEGK
                     TAAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAATKQV"
     gene            complement(39305..40111)
                     /gene="tcdA"
                     /locus_tag="RH288_000127"
     CDS             complement(39305..40111)
                     /gene="tcdA"
                     /locus_tag="RH288_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HDV4029234.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
                     PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGT
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG"
     gene            complement(40350..41447)
                     /gene="mltA"
                     /locus_tag="RH288_000128"
     CDS             complement(40350..41447)
                     /gene="mltA"
                     /locus_tag="RH288_000128"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HDV4029235.1"
                     /translation="MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGI
                     DAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGA
                     LSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDR
                     GEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG"
     gene            41656..41732
                     /locus_tag="RH288_000129"
     tRNA            41656..41732
                     /locus_tag="RH288_000129"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41690..41692,aa:Met,seq:cat)
     gene            complement(41806..43059)
                     /gene="amiC"
                     /locus_tag="RH288_000130"
     CDS             complement(41806..43059)
                     /gene="amiC"
                     /locus_tag="RH288_000130"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HDV4029236.1"
                     /translation="MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPA
                     SSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSAR
                     VGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
                     YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQI
                     ARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQ
                     QEVAESILAGIKAYFADGATLARRG"
     gene            43291..44622
                     /gene="argA"
                     /locus_tag="RH288_000131"
     CDS             43291..44622
                     /gene="argA"
                     /locus_tag="RH288_000131"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HDV4029237.1"
                     /translation="MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSS
                     IVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAG
                     TLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
                     IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDD
                     GDIVSELFPNEAQARVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGAL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQS
                     GLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG"
     gene            complement(44684..46510)
                     /gene="recD"
                     /locus_tag="RH288_000132"
     CDS             complement(44684..46510)
                     /gene="recD"
                     /locus_tag="RH288_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HDV4029238.1"
                     /translation="MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSH
                     DAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMIL
                     CGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGK
                     ALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTG
                     THVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTD
                     IEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFG
                     VAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGT
                     RVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELV
                     YTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE"
     gene            complement(46510..50052)
                     /gene="recB"
                     /locus_tag="RH288_000133"
     CDS             complement(46510..50052)
                     /gene="recB"
                     /locus_tag="RH288_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HDV4029239.1"
                     /translation="MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYERLLE
                     EIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETL
                     ASRHAQIVARIDTVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIDKISAWAEEE
                     TNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAE
                     IRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSA
                     PGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLMEGES
                     CGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQ
                     VRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLN
                     ALDIETLNNDEHAWDVVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITNFRVQEQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAED
                     LRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTC
                     IEALCDDDIAWQTAQTGDNQPWQVNDVSTAELNAKTLQRLPGDNWRVTSYSGLQQRGH
                     GIAQDLMPRLDVDAAGVASVVEEPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNW
                     VREKLELGGFESQWEPVLTEWITAVLQAPLNETGVSLSQLSARNKQVEMEFYLPISEP
                     LIASQLDTLIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGE
                     DSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYEHHFGGVIYLFLRGV
                     DKEHPQQGIYTTRPNAGLIALMDEMFAGMTLEEA"
     gene            complement(50045..52933)
                     /gene="ptrA"
                     /locus_tag="RH288_000134"
     CDS             complement(50045..52933)
                     /gene="ptrA"
                     /locus_tag="RH288_000134"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HDV4029240.1"
                     /translation="MPRSTWFKALLLLVALWAPLSQAETGWQPIQETIRKSDKDNRQY
                     QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP
                     QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQAL
                     KDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVE
                     GISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDEL
                     ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMT
                     PQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPELNPYIP
                     DDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQ
                     VMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGY
                     FSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSI
                     TLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVD
                     KKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQ
                     AVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVV
                     EPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE"
     gene            complement(53109..56477)
                     /gene="recC"
                     /locus_tag="RH288_000135"
     CDS             complement(53109..56477)
                     /gene="recC"
                     /locus_tag="RH288_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HDV4029241.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEIPKESAFNKQSMSWKLMTLLPQL
                     LEREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE
                     AQAWQAPLWKALVEYTHQLGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISA
                     LPPVYLQALQALGKHIEIHLLFTNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPL
                     FRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESSQELDAFVDVTPDNL
                     LHNIQSDILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHDR
                     LLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPV
                     LEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLRYLRQWVNESGIRWGIDD
                     DNVRELELPATGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGL
                     GAQYGDAVPLSLLRDELAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNS
                     ERFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGE
                     RQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVN
                     FRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGE
                     IFWETQCQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQPDGLLRWRPSLL
                     SVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREG
                     MSAPLLVLPESGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDI
                     WYQRLWRQLTPETMEAIVEQSQRFLLPLFRFNQS"
     gene            complement(56490..56813)
                     /locus_tag="RH288_000136"
     CDS             complement(56490..56813)
                     /locus_tag="RH288_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDV4029242.1"
                     /translation="MSASLKNQQGFSLPEVMLAMVLMVMIVTALSGFQRTLMNSLASR
                     NQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLH
                     CPNRQ"
     gene            complement(56798..57205)
                     /locus_tag="RH288_000137"
     CDS             complement(56798..57205)
                     /locus_tag="RH288_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417301.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HDV4029243.1"
                     /translation="MNREKGVSSLALVLMLLVLGSLLLQGMSQQDRSFASRVSMESQS
                     LRRQAIVQSALAWGKMHSWQTQPAVQCSQYAETDAQVCLRLLADNEALLIAGYEGVSL
                     WRTGEVIDGNIVFSPRGWSDFCPLKERALCQLP"
     gene            complement(57202..57765)
                     /locus_tag="RH288_000138"
     CDS             complement(57202..57765)
                     /locus_tag="RH288_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HDV4029244.1"
                     /translation="MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTSTRK
                     LALEDEIWLRVFTVAKHLQRAGYCHGICTGEGLEIVGQGDCVIVQWDANSNGIWDREP
                     VKESDQIGFRLKEHVLETLRGATSCEGKGWDKVTNPDAIIIDTFQVVRQDVSGFSPVL
                     TVNMRAASKSEPQTVVNASYSVTGFNL"
     gene            complement(57756..58226)
                     /locus_tag="RH288_000139"
     CDS             complement(57756..58226)
                     /locus_tag="RH288_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HDV4029245.1"
                     /translation="MKTQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTAS
                     QARDYLLYLREDANWHNRDHSISVIREGTLWCLVSSAAGANTCHGSSPLVFVPRWPEV
                     EMSDLTPSLAFFGLRNTAWAGHIRFKNSTGEWWLVVSPWGRLRLCQQGETEGCL"
     gene            complement(58410..59204)
                     /gene="thyA"
                     /locus_tag="RH288_000140"
     CDS             complement(58410..59204)
                     /gene="thyA"
                     /locus_tag="RH288_000140"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDV4029246.1"
                     /translation="MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHL
                     QLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI"
     gene            complement(59211..60086)
                     /gene="lgt"
                     /locus_tag="RH288_000141"
     CDS             complement(59211..60086)
                     /gene="lgt"
                     /locus_tag="RH288_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDV4029247.1"
                     /translation="MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
                     HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
                     PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVI
                     MMVWAYRRSPQQHVS"
     gene            complement(60237..62483)
                     /gene="ptsP"
                     /locus_tag="RH288_000142"
     CDS             complement(60237..62483)
                     /gene="ptsP"
                     /locus_tag="RH288_000142"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDV4029248.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
                     ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVI
                     EKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWPERFILVADELSATT
                     LAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGE
                     LLVDPEPVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVD
                     EARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQ
                     YILAVDRNNTRVANIYDSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARAKYLLRRIDYAEAENLAQRSLEAQLATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(62496..63026)
                     /gene="rppH"
                     /locus_tag="RH288_000143"
     CDS             complement(62496..63026)
                     /gene="rppH"
                     /locus_tag="RH288_000143"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HDV4029249.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQE
                     NTPKPQNASAYRRKRG"
     gene            63711..64400
                     /gene="mutH"
                     /locus_tag="RH288_000144"
     CDS             63711..64400
                     /gene="mutH"
                     /locus_tag="RH288_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HDV4029250.1"
                     /translation="MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALVGLVTPENL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEE
                     LMDMIVLGQVERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFT
                     SALLARHFLIQ"
     gene            64469..65182
                     /locus_tag="RH288_000145"
     CDS             64469..65182
                     /locus_tag="RH288_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDV4029251.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTIFSQEISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAM
                     FFSIAVESLNLIRNKKNPL"
     gene            65320..65538
                     /gene="ygdR"
                     /locus_tag="RH288_000146"
     CDS             65320..65538
                     /gene="ygdR"
                     /locus_tag="RH288_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YgdR"
                     /protein_id="HDV4029252.1"
                     /translation="MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDD
                     DTGLVSYHDQQGNAMQINRDDVSQIIER"
     gene            65646..66686
                     /locus_tag="RH288_000147"
     CDS             65646..66686
                     /locus_tag="RH288_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HDV4029253.1"
                     /translation="MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGI
                     NLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPD
                     QALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
                     LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVG
                     LAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAA
                     YVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEI
                     EAVHQVYTYPAP"
     gene            complement(66718..67911)
                     /gene="lplT"
                     /locus_tag="RH288_000148"
     CDS             complement(66718..67911)
                     /gene="lplT"
                     /locus_tag="RH288_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HDV4029254.1"
                     /translation="MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINP
                     FLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGET
                     RFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMIGIPVVPIGIGFGALFALAITALWI
                     WQRRH"
     gene            complement(67904..70063)
                     /gene="aas"
                     /locus_tag="RH288_000149"
     CDS             complement(67904..70063)
                     /gene="aas"
                     /locus_tag="RH288_000149"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HDV4029255.1"
                     /translation="MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGIL
                     LGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVI
                     FPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
                     TLHILPPTQVAMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFG
                     AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAI
                     ARRRMPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPEL
                     AVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE"
     gene            70648..71679
                     /gene="galR"
                     /locus_tag="RH288_000150"
     CDS             70648..71679
                     /gene="galR"
                     /locus_tag="RH288_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HDV4029256.1"
                     /translation="MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLS
                     YHPNANARALAQQTTETVGLVVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQMPGMVLINRILPGFENRCIALDD
                     RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIAANDRLVTFGE
                     PDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVL
                     VSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFSPTLVRRHSVSTPSL
                     EASHHATSD"
     gene            complement(71686..72948)
                     /gene="lysA"
                     /locus_tag="RH288_000151"
     CDS             complement(71686..72948)
                     /gene="lysA"
                     /locus_tag="RH288_000151"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDV4029257.1"
                     /translation="MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALK
                     QFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTAD
                     VIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVIEFGQD
                     LQAISAGGGLSVPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQ
                     SGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVE
                     TVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALELL"
     gene            73070..74005
                     /gene="lysR"
                     /locus_tag="RH288_000152"
     CDS             73070..74005
                     /gene="lysR"
                     /locus_tag="RH288_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator LysR"
                     /protein_id="HDV4029258.1"
                     /translation="MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEK
                     VIGLKLFERVRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
                     TELLSLDEVCVLPPGHPLAVKKVLTPDDFQGENYISLSRTDSYRQLLDQLFTEHQVKR
                     RMIVETHSAASVCAMVRAGVGVSVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLH
                     RPSSALVQAFSGHLQAGLPKLVTSLDAILSSATTA"
     gene            complement(73992..74684)
                     /gene="ygeA"
                     /locus_tag="RH288_000153"
     CDS             complement(73992..74684)
                     /gene="ygeA"
                     /locus_tag="RH288_000153"
                     /EC_number="5.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDV4029259.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVD
                     FHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCTLPFL
                     HIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQI
                     IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAA
                     IHAEDAVAFMLS"
     gene            complement(74813..76231)
                     /gene="araE"
                     /locus_tag="RH288_000154"
     CDS             complement(74813..76231)
                     /gene="araE"
                     /locus_tag="RH288_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HDV4029260.1"
                     /translation="MVTINTESALTPRSLRDTRRMNMFVSVAAAVAGLLFGLDIGVIA
                     GALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLG
                     SIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
                     IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVL
                     RMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNI
                     IMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVM
                     ALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKC
                     RDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETK
                     NVTLEHIERKLMAGEKLRNIGV"
     gene            complement(76546..77307)
                     /gene="kduD"
                     /locus_tag="RH288_000155"
     CDS             complement(76546..77307)
                     /gene="kduD"
                     /locus_tag="RH288_000155"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HDV4029261.1"
                     /translation="MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVE
                     PTETIEQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDAL
                     EFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRW
                     GLPSDLMGPIVFLASSASDYVNGYTIAVDGGWLAR"
     gene            complement(77337..78173)
                     /gene="kduI"
                     /locus_tag="RH288_000156"
     CDS             complement(77337..78173)
                     /gene="kduI"
                     /locus_tag="RH288_000156"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HDV4029262.1"
                     /translation="MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDR
                     IIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRD
                     ALYVGKGAKEVVFASIDTGTPAKFYYNCAPAHTAYPTKKVTPDEVSPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFH
                     MMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKD
                     LR"
     gene            complement(78460..79641)
                     /locus_tag="RH288_000157"
     CDS             complement(78460..79641)
                     /locus_tag="RH288_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417321.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDV4029263.1"
                     /translation="MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVP
                     AYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQ
                     PRTDASAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERVGWQLAEVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERD
                     E"
     gene            79896..81125
                     /locus_tag="RH288_000158"
     CDS             79896..81125
                     /locus_tag="RH288_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HDV4029264.1"
                     /translation="MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGNLITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
                     IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDR
                     REKYGEHAMDKCKKIMKVAYLIICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALS
                     MLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTLQQVGVKKSRAFNRA
                     LSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSIGN
                     LITLIVGILCVSVMFFS"
     gene            81585..82217
                     /locus_tag="RH288_000159"
     CDS             81585..82217
                     /locus_tag="RH288_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV4029265.1"
                     /translation="MGLCSRYKSLTCNSCSMHCQIMPEESPRLQYCANSCFCMWPEES
                     SYFNRGVVEGILTKNHNARLSGYIFVDFSVSFLRLFLEKDWIDYLASTDMGIVLVSDR
                     NMQSLANYWRKHNSAISAVIYNDDGLDVANEKIRQLFIGRYLSFTRGNTLTQMEFTIM
                     GYMVSGYNPYQIAEVLDMDIRSIYAYKQRIEKRMGGKINELFIRSHSVQH"
BASE COUNT        20345 a        22012 c        19936 g        20123 t
ORIGIN      
        1 ttcactttcg tatgttcctt tgttgcagcc caaccaacta ttgtcccaca attacagcaa
       61 caagttacgg atcttacgag tagcttaaac tcacaagaaa agaaagaact gacgcacaag
      121 ttagaatcta ttttcaataa tacccaagtg caaattgccg tattaattgt tcccacaacc
      181 aaagacgaga caattgaaca atatgctaca agagtttttg acaattggcg tttaggagat
      241 gccaaacgta atgatgggat actgatcgtt gttgcctggt cggatcgcac tgtccgcatc
      301 caggtaggtt atgggctgga agaaaaggta accgatgctc tggctggaga tatcatccgt
      361 agcaacatga tacccgcatt taaacaacaa aaattagcta agggattaga gctagctata
      421 aacgctttga ataaccaact cacttcacaa caccaatatc cgactaatcc ttcagaaagt
      481 gaatcagcgt cttccagtga tcattattac tttgctattt tttgggtatt tgcagtgatg
      541 ttcttccctt tctggttttt tcatcaaggc agtaattttt gtcgcgcatg taaaagtgga
      601 gtctgtattt cagcaatcta tcttttagat ttattcctgt tctccgataa aattttttcc
      661 attgctgtat tttccttctt ttttactttc accatattta tggtctttac ctgtttatgt
      721 gtacttcaga aaagagcatc tggtagaagt tatcattcag acaacagcgg ttccgctgga
      781 ggctcagata gcggcggatt tagcggcggg ggcggttctt ctggaggtgg cggcgcatcc
      841 ggccgctggt aactcaacca taaaaaatgc cagcccggag gctggcattt ttaaatcaga
      901 taaagtcagt cttatgcctg gcctttgatc tctttacgac cgttgtacgg tgctttttcg
      961 cccagagctt cttcgatacg aatcagctgg ttgtatttag caacacggtc agaacggctc
     1021 atagaaccag ttttgatctg gcctgcagca gtaccaacag ccaggtcagc gatggtagcg
     1081 tcttcagttt cgccagaacg gtgagagata actgcagtgt agccagcatc tttcgccatc
     1141 ttgattgcag ccagagtttc ggtcagagaa ccgatctggt tgaatttgat caggatggag
     1201 ttagcgatac ctttttcgat accttctttc aggatcttgg tgttggttac gaacaggtcg
     1261 tcaccaacca gctggatttt gtcgcccaga actttggtct ggtatgcgaa accgtcccag
     1321 tcagattcgt ccagaccgtc ttcgatagaa acgatcgggt actgtttggt cagttcttcc
     1381 aggaagtgag tgaattcttc agaggtgaac gctttgttgc cttcgccagc cagaacgtat
     1441 ttaccatctt tgtagaattc agaagctgcg cagtccatcg ccaaagtgat gtctttgccc
     1501 agttcataac cagcagcttt aacagcttca gcgataacag ccagagcttc agcgttggaa
     1561 cccaggttcg gcgcatagcc accttcgtca ccaacagcag tgttcatgcc tttcgctttc
     1621 agaacttttg ccaggtgatg gaaaacttca gaacccatgc ggatggcttc tttcacagtt
     1681 ttcgcgccaa ccggctgaat catgaattcc tggatatcaa cgttgttgtc agcgtgctca
     1741 ccaccgttga tgatgttcat catcggaacc ggcatagagt atttgcccgg agtaccgttc
     1801 agttcagcga tgtgctcgta cagcggcata cctttagcag ctgcagcagc tttggcgtta
     1861 gccagagata cagccaggat tgcgttcgcg ccgaatttgg atttgttttc ggtgccgtcc
     1921 aggtcgatca tgatcttgtc aatgccagcc tgatctttag catctttgcc aatcagcgcc
     1981 tgagcgatcg ggccgtttac cgcagcaaca gctttggtta cgcctttacc caggaaacgg
     2041 gatttgtcgc catcgcgcag ttccagagct tcacgggaac cagtagaagc acctgacgga
     2101 gcagctgcca taccgacgaa accaccctcc agatgtactt cggcttcaac agtcgggtta
     2161 ccacgggagt cgatgatttc acgaccgatg atttttacga ttttggacat taggttttcc
     2221 tcaagtcact agttaaactg aaactccaga caaacaacgc gtacccaggg tacgcgttgc
     2281 cgctctaact tttttactta cttcgcctga cgtttctgga actcgctggc ggctttcaca
     2341 aagcctgcaa acagcgggtg accatcacgt ggagtagaag taaactccgg atggaactgg
     2401 caagccacga accacgggtg attcggaact tcgatgatct cgaccaactg atcatccccg
     2461 gaacggcccg caacgcgcag acctgcatct tcaatctgtt tcaacagcat gttgttgact
     2521 tcgtaacggt gacgatgacg ctcaacaatt gtcggcgcat tgtacagctg gcgaaccagg
     2581 ctatcgtcaa ccaactggca ctgctgtgcg ccgagacgca tggtaccgcc gagatcgctc
     2641 ttctcgctac gaacttcaac gttgccgttt tcatcgcgcc actcggtaat cagcgccaca
     2701 accgggtact tacagtctgg cacaaattcc gtagagttgg cgttctccat gttggcaaca
     2761 tggcgagcgt aatcaattaa cgccacctgc atacccaggc aaatgcccag ataaggaata
     2821 ttgttctcac gcgcaaaacg cgcggtcgta atcatgcctt ctacgccacg atagccgaaa
     2881 ccgccaggta cgaggattgc gtccagacct ttaaggattt caacgccgcg cgtttcaaca
     2941 tcttgtgaat cgatcagttt gatgttgacg ctgacacgat tcttcagccc accgtgtttc
     3001 agtgcttcga tcactgattt ataagcatcc ggcagttcaa tgtacttgcc gaccataccg
     3061 atggtgactt cacttaccgg gttcgcttct tcgaagataa cctgttccca ttcggacaga
     3121 ttcgcttccg ggcagtttaa gctgaatcgt ttacaaatat aatcgtccag cccctgagat
     3181 ttcaacaggc ccggaatttt atagatggaa tcgacgtctt tcagagaaat aaccgctttt
     3241 tccggaacat tacagaacaa tgcaatcttc gcacgttcgt tcgccggaac agcgcgatct
     3301 gaacgacaaa tcaggatgtc aggctggata ccgatggaga gcagctcttt tacagagtgc
     3361 tgagtcggtt tggttttgac ttcaccagac gctgccatgt acggcaccag cgtcaggtgc
     3421 ataaacagag tgtgctcacg gccaatttca acagccatct ggcgaatcgc ttcgaggaac
     3481 ggcaaggatt cgatatcacc tactgtaccg ccgatttcta ccagtactac gtcatgacct
     3541 tcgccacctt ccagcacgcg ctctttgatt gcgttagtga tgtgcggaat aacctgcacg
     3601 gttgcgccga ggtagtcacc gcggcgttct ttacgcagaa cgtcagagta gatacgaccc
     3661 gtggtgaagt tgttgcggcg gctcattttg gtacgaatga aacgctcgta gtgccccagg
     3721 tccaggtcgg tttcagcgcc gtcttcagta acgaacactt ccccgtgttg gattgggctc
     3781 atagtacctg gatcgacgtt gatgtacgga tccagtttca tgatggtcac attgaggcca
     3841 cgggcttcaa gaatggctgc gagggaggct gcggcaatgc ctttacccag agaggatacg
     3901 accccgccgg tcacaaaaat atagttcgtt gtcatgctga acctgagaag ttaggttgaa
     3961 aagacgatgg aataaccaag acgggaaagc agtatacccg aacatgacct gtgccacaaa
     4021 ctttcattat ccctcctctt cgccagcgca ctattgaaat caggagtgag aaaatagccc
     4081 ctttggggta aatgtttttg acgcaaatca agcgcttgtc atttaaaaaa tgacacaaat
     4141 ggcgcttgac cgcgtaattc ccttagagat caatttcctg ccgttttacc tgttgccaga
     4201 cttcttccat tgtttcgagg tcaacacctg tcatttccag tccacgcgcg gcaacaatac
     4261 gctccacttc gcgaaaacga cgctcgaatt tttcgttcgc tttttgcaat gcgatttctg
     4321 ctttcgtccc taaatggcga gccagattaa ccgtggcaaa cagcaggtcc cccatttcct
     4381 cctccagttt agcctggtcg acaacagcct gccgcgcttc gtacatcacc tcgtcgatct
     4441 cttcgtagac tttatcgact accggaccaa gcgtcgtcca atcgaagcca acgttggcgc
     4501 aacgtttctg gattttttgc gcacgcatta aagccggtaa actacgagga atatcgtcca
     4561 gcgccgaatg ctgcgctttc tgcgcgcgct cttcggtttt gatttgctcc caacgggcaa
     4621 gcacttcact actgttttcg gcagaactat cagcaaaaac atgcggatgg cgacgctcta
     4681 atttatcgct aatagcagcg caaatatcat taaagtcaaa gcgcccttct tcctgagcca
     4741 tttgcgcgta aaacaccacc tggaatagca gatcgcccag ttcaccgcga agatcgtcaa
     4801 aatcttcacg ggcgatggcg tccagcactt cgtaggtttc ttcaagggtg taaggcgcaa
     4861 tggtggcaaa tgtctgctct ttatcccacg ggcagccgtt ttccggatcg cgcaggcgct
     4921 gcataatagt gagcaaacgg tcgatttgat tcattgaatt gtcctgaaaa ttgcgggtct
     4981 gtcaggtgga aacctgtgac cagaatagaa gtgagttagt aacactaccc aatcagtacg
     5041 ttaattttgg ctttaatgag ttgtaattcc tctggggcaa ctgttccttt cttcgttgct
     5101 cctcttgccc gccaggcgat actttttacc tgatcagcta acgctacgcc atcacgttcc
     5161 tgaccggata aaacaacttc gaacggatat ccttttgatt gcgttgtaca aggaacacac
     5221 agacacatac ctgttttgtt gttgtacatg aaaggactca ggacaacaac tggacgatgt
     5281 ccagcttgct cgctaccttt tgtcgggtca aaatcaaccc aaatcagatc gcccatatcg
     5341 ggtacgtatc ggcttaccat taccagactt ccttatcttt cggctctccc cagtcgatat
     5401 tctcgtggag gttttccggc gtgatgtcgt tgaccagttc agcaagcgta aatacgggct
     5461 ctttacgcac tggctcaata attaatttgc catccaccag gtcaatcttc acttcatcat
     5521 caatattcag attgagcgcc tgcattaacg tagccgggat ccgcaccgcc ggtgaatttc
     5581 cccaacgctt tacgctactg tggatcataa ccctttcctc aaaccgctat catatgtaga
     5641 tacagtatat atcaatctac attgtagata cgagcaaatt tcggcctaac tcccgtgcaa
     5701 ccgacgcgcg tcgataacat ccggcacctg gttgagttta cccagcacgc gccccagcac
     5761 ttgcaggttg taaatctcaa tggtcatgtc gatggtcgcc agttgctgtt tggtgtcgct
     5821 acggctggca acgccaagca cgttcacctt ctcgttggcg agaatggtcg tgatatcacg
     5881 taacaaccca ctacgatcat tagctaccac gcggaccacc agcgaatatc cggcggagta
     5941 gctctcaccc cataccgcgt caacaatgcg ttctggcgca tgggagcgca gttccgccag
     6001 ttgttcgcaa tcggcgcggt gtactgaaat accgcgcccc tgggtaatga agccgacaat
     6061 ctcatctcca ggaatcggct ggcagcagcg cgcgatgtgg tgcatcaggt tgccaacacc
     6121 ttcgactacc acgcgaccgt tatctttact gcggttttgc ggcgtgtagc ttttttgctg
     6181 aagttgcttc agcgcggcgg cgtcctgctc ttcggcactc ggcttattaa attgcgattg
     6241 caggaagttc accatctgat tgagacggat atccccgcca ccaatcgccg ccagcaactc
     6301 gtcgacatca ttgaagttgt aacgcggcag cagatgtttt tctgcttctt tcaggctgat
     6361 ccccagatgt tccagctcgt cgtcaaggat ttgccgccca gccagaatgt ttttgtcacg
     6421 gtcctgttta cggaaccagg cgtgaatttt cgaacgccca cggctggttg tgacgtaacc
     6481 gaggtttggg tttaaccagt cacggctggg gttcggctgt ttctgggtga taatttcaat
     6541 ctggtcgccc atctgcagct ggtaggtgaa cggcacaatg cgcccgccaa tttttgcccc
     6601 gatgcagcgg tgtccgacat cactgtggat gtggtaagcg aagtccagcg gcgttgatcc
     6661 cgcaggcaaa tcaacgacat cacctttcgg cgtaaagacg tacacccggt cgtcaaagac
     6721 ctgactacgt acttcgtcga gcatttcgcc ggaatcagcc atctcttcct gccacgcaat
     6781 cagtttacgc agccaggcaa tccggtcttc atgtcccgaa cgtgcgccgc cagcagccgc
     6841 gccctcttta tatttccagt gcgcagcaac acccaactct gcatcttcat gcatctgttt
     6901 ggtgcggatt tggatctcaa cggtttttcc acccggcccc agaaccacgg tatgaataga
     6961 ctgataaccg tttggtttcg ggttagcgac gtaatcgtca aactcatccg gcaggtggcg
     7021 atagtgagtg tgcactatcc ccagtgcggc atagcaatcc tgtaaacgct cggcgacaat
     7081 acgtaccgca cgcacatcaa acagctcatc aaaggcgagg ttctttttct gcattttacg
     7141 ccagatgctg tagatgtgtt tcggacgacc atacacttcc gctttaacgc cttcagcttt
     7201 catctcagcg cgcagatgac caacgaactc ttcgatgtag tgttcgcggt cgagacgccg
     7261 ttcatgcagc agtttggcaa ttcgtttgta ttcggttgga tggaggtaac ggaagcagta
     7321 atcttccagt tcccatttca gttgtccgat tccgagacgg ttagccagcg gtgcgtagat
     7381 gttggtacac tcttttgccg ccagtacacg ttcatcttcc ggcgcatctt ttacttcgcg
     7441 cagatgagca atacgctccg ccagtttgat gactacgcag cgaaaatcat cgaccatcgc
     7501 caataacatc cggcgaacgt tatcgacctg ttcggaggaa acagaatcag tgtgcgtcgc
     7561 tttcagctgg cggatcgccg ccatatcacg cacgccgtga ataaggttaa cgaccgactt
     7621 accgacgctc tcacgcagca catcttcgct gactacgttg gcatccgcca gagggaaaag
     7681 cagcgccgcc cgcagcgtgt caatgtccat acttaatgtc gagaggatct ccaccatctc
     7741 aacaccacgc cacaataaca gactggcatc cggatgcccc tgcgtctgtt gcagacaata
     7801 cgcccaggtt tcggctaagc actcacacga cttctggctg gtaataccca gacttgcgat
     7861 ccatttttcc ggatcaaatt caccagcctt attgatatgt gcacttctta ccgcaaccat
     7921 cgtcctctcc tttagggacc agacctgccg aaatcggcaa atcgcaacta tttaacgcgc
     7981 gagaaaagta ccatcgattc cagatgtccc gtgtgtggga acatatccag catcgccagt
     8041 cgcgcaatgg tatatcctgc ttttaataac gcttcgctat cccgagccag cgttgcaggg
     8101 ttacaggata cataaactat acgaataggt tccagtttta taatttgctg cataacacct
     8161 gcggcacctg ctcgcgccgg gtccagcaac actttatcga agccgttttt cgcccacggc
     8221 tgctttgtga catcttcttc aagattttcg tgataaaacg tcacattctg taagccatta
     8281 agacgcgcat tctgctggcc tttttccacc agcgccggaa caccttctac accgaccaca
     8341 ctggcagctt gtgtcgccaa tggcagtgta aagttgccca taccgcagaa cagatccagt
     8401 acgcgatctt caggttgcac gtccagccat tccaacgcac gcgctaccat tttttggttc
     8461 acacccgcat tgacctgaat aaaatcgcgc gggctaaaag ttaagcgcaa cccgtttgag
     8521 tcataccagg gcatctcacc agagacggtt tcgagtatct cactatcggg ggcgagatac
     8581 agatccaggc cttcagaatg cgaaaagcgt tccagttttt cgcgatctgc cgaacttagc
     8641 ggtgcggtat ggcgcaaaat catcagcgtg ccgctggttg cctgtaccag ttcaacatga
     8701 ccaagatggc gcatagcttg taagctgccc agacatgccc tgactttggg cagcaatgct
     8761 tcaagttggg gcgctaaaat ggggcattgt ttgacgtcga caatgtcact ggagcccgct
     8821 ttgcgaaacc ccatctgaag ttgctgtgtt ttcggtaagt agttcagact taaacgcgcg
     8881 cgacggcgat agccccaggg aacatcggcg atcacttcag agacatcgtg tttcattaat
     8941 cgggcgagtg ccgcactttt gcttcgctgc tgtaaatcca cgctggcgtg ttgttgctga
     9001 cagccaccgc atacgccaaa atgaggacag cgtggcgttt cgcgttccgg gctatcgctt
     9061 aaccggcgta cgactttagc gcgggcatac tgttttttat cttcagtaac agtaacttcc
     9121 gcgttttcct gcggcaataa tccggggata aatagcgttt tgccgttatg tcgcgccacg
     9181 ccctgaccaa aagagtcgag gtcgttgact gaaacggtta tgatctgacg cgtcgtcgtg
     9241 cgtcgttttg cagagtagaa ttgcgccatt ggcgagactt tctcaattta acagtgtgac
     9301 cttaattgtc ccataacgga actccatgac caactacagc ctgcgcgcac gcatgatgat
     9361 tctgatcctg gcaccgaccg tccttattgg tttattgctg agtatctttt tcgtcgtgca
     9421 tcgctataac gacttgcagc gtcaactgga agatgccggt gccagcatta ttgagccgct
     9481 tgcagtttct actgaatatg gcatgagcct gcaaaatcgc gaatctatcg gtcagttaat
     9541 aagcgtactg catcgtcgcc attccgatat tgttcgcgcg atttcggttt atgatgaaaa
     9601 taaccgactc tttgtcacct ccaattttca tcttgatccc tcatcaatgc agctcggcag
     9661 caacgtgccg tttcctcgcc agctcactgt cactcgtgac ggcgatatta tgatcctccg
     9721 cacgccgatt atttctgaga gttactcccc cgacgaatcg cccagtagcg atgccaaaaa
     9781 tagtcaaaat atgttgggat atattgcgct ggagctggat cttaaatcgg ttcgcttgca
     9841 gcaatataaa gagatcttta tttccagcgt gatgatgctg ttttgtatcg gtattgcgct
     9901 tatttttggc tggcgcttaa tgcgcgatgt aaccggtccg attcgcaaca tggtgaatac
     9961 cgtcgaccgc atccgtcgcg ggcaactcga cagccgggtg gaaggattta tgctcggcga
    10021 gctggatatg ctgaaaaacg gtatcaactc gatggcaatg tcgctggctg cttatcacga
    10081 agagatgcag cacaatatcg accaggcgac gtccgatctg cgtgaaacgc tggagcagat
    10141 ggaaattcag aacgttgagt tagatctggc gaaaaagcgc gcccaggaag cggcgcgtat
    10201 taaatccgag tttctggcaa atatgtcaca cgagctgcgt acaccactga atggtgttat
    10261 tggctttacc cgcctgacgc tgaaaacaga attaacacca acgcagcgcg atcacctgaa
    10321 tacgattgaa cgttcggcaa ataatttgct ggcaattatt aatgatgttc tcgacttctc
    10381 gaaactggaa gcaggtaagc tgattctgga aagtattcca ttcccactac gcagcacgct
    10441 ggatgaagtc gttactctgc tggcacattc ttctcacgat aaagggttag aactgacgct
    10501 caatattaaa agcgacgtgc ctgataacgt gatcggcgac ccgctgcgat tacagcaaat
    10561 catcactaac ctggtgggga atgcaattaa attcaccgag aatggcaaca ttgatattct
    10621 ggtagaaaaa cgtgcgctga gtaataccaa agtgcagatt gaagtgcaga ttcgggatac
    10681 cggcattggt attcctgaac gcgatcaatc gcgcttattc caggccttcc gacaggctga
    10741 tgccagtatt tcccgccgtc atggtggcac cgggctgggg ctggtgatta cacaaaaact
    10801 ggttaatgaa atgggcggcg atatttcgtt ccatagccag ccgaatcgcg gttcaacttt
    10861 ctggttccac attaatctcg atctgaaccc gaacattatt atcgaagggc catccaccca
    10921 gtgcctcgca ggtaagcgcc tggcctatgt cgaaccaaac tccgcagcag cgcaatgcac
    10981 gctggatatt ttaagtgaaa cgccgctgga agtggtttat agcccaacgt tctccgcgct
    11041 gcctcccgcg cattacgaca tgatgttgtt aggcatcgcg gtgaccttcc gcgagccgct
    11101 aacaatgcaa catgagcgat tagcgaaagc ggtatcgatg accgatttcc tgatgctggc
    11161 acttccttgc catgcacaag tcaatgctga aaaactcaag caagatggta tcggcgcgtg
    11221 tctgctgaaa ccattaacac ctacacgcct gttgcctgcc ctgacggaat tttgtcatca
    11281 caaacaaaac acgcttttgc ctgtaaccga tgaaagtaag ctggcaatga cagtcatggc
    11341 ggttgatgac aaccccgcta acctgaaact tatcggcgca ttgctggaag atatggtgca
    11401 acatgtggaa ctttgcgata gcgggcatca ggcggttgaa cgggcgaaac agatgccgtt
    11461 cgatttgatc ttaatggata ttcaaatgcc ggacatggat ggcattcggg cctgcgaact
    11521 catccaccaa ctcccgcatc agcaacaaac gccggttatc gcggtaacgg cgcatgcaat
    11581 ggccgggcaa aaagagaagc tgcttggcgc agggatgagc gattatctgg cgaaaccgat
    11641 tgaagaagag cgattgcata atttgttgtt gcgctacaag cctggcagcg gtatttcctc
    11701 tcgcgtcgtg acgcccgaag tcaacgaaat tgtggtgaac ccgaatgcga ccctcgactg
    11761 gcaactggca ctacgccagg cagcaggaaa aaccgattta gcgcgcgata tgctgcaaat
    11821 gttactcgat ttcctgcctg aagttcgcaa caaagttgag gaacagctgg ttggagaaaa
    11881 cccggaaggc ctggttgatt tgattcataa actgcatggc agttgcggct atagcggtgt
    11941 gccacgtatg aagaatctct gccaactgat cgaacaacag ctacgtagcg gtactaaaga
    12001 agaagatttg gaaccggagc tgctggaact gttggacgag atggataatg tcgcgcgcga
    12061 agccagcaaa attctcgggt aatggatgtc ttgtcgagta gcaatcggct ttttatgacg
    12121 ctggtttcag attggtgaca aagtgcctgt gtttatgccg gatgcggcgt taacgcctta
    12181 tccggcctac aaaaccaatt aaattcaatg aattaaaaaa tgatgtagac ctgatacata
    12241 gcacaacagg ctattttgcg tttagcatca gtctcaaacc ggctccagat agagccggtt
    12301 ttggttttct gtcttaacgc accatgcacg ggcgcttgtt atcgaacgtc cagccaggaa
    12361 tcagatactg cattcccatc gcatcgtcac gcgcgccaag cccgtgtttc tgatacagct
    12421 catgggcttt catcacttga tccatatcga tttctacacc cagccccggt ttttctggca
    12481 cctgtaccag cccgcctttg atctcaaacg gttctttggt caggcgctga ttgccttcct
    12541 gccaaatcca gtgcgtatca atagcagtaa ttttacccgg tgcagcggcg gcaacatggg
    12601 taaacatcgc cagggaaata tcgaagtggt tgttagagtg tgaaccccag gtcaggccaa
    12661 attcatggca catttgcgcc acacgtaccg aaccttgcat tgtccagaaa tgcggatccg
    12721 ccagcgggat atcaacggat tgcagggaga gcgtatggcc catttgccgc cagtcggtgg
    12781 cgatcatatt ggttgcagtc ggtagacctg tcgcgcgacg gaactctgcc atcacttcac
    12841 gcccggagaa accttgctcc gcaccacacg gatcttctgc ataagccagc gaacctttca
    12901 ggtatttacc gattttaatc gcttcgttca gcgaccaggc accgttagga tcgagcgtaa
    12961 tacgcgcctg cgggaagcgt tgcgccagtg ccacaataga ctcggcctct tcttccccgg
    13021 ccagtacacc gcccttcagt ttgaaatcgt tgaagccata tttttcatat gccgcttccg
    13081 ccaggcgcac caccgcatcc ggcgtcatcg cttcttcatg acgcaggcga taccagtcgc
    13141 atgagtcatc cggctggctt tgatacggca gcggcgtggc tttgcgatta ccgacgaaga
    13201 acagataacc gagcatttcg acttcgctac gctgttgacc atcgcccagc agcgatgcca
    13261 cgtttacccc cagatgctgc cccagcagat ccagcattgc cgcttctatc ccggtaacta
    13321 catgaatagt ggtacgtagg tcaaatgtct gcaaaccgcg cccaccagca tcacgatcgg
    13381 caaaagtatt acgcaccagc gtcagaacgt ttttgtattc acccagcgtt ttacctacca
    13441 ccagcggaat cgcatcttcc agcgttttac ggattttctc gccgccggga atttccccta
    13501 cgccagtgtg accagaatta tctttgataa tcacaatatt acgcgtaaag aacggtgcgt
    13561 gtgcaccact cagattcatc agcatactgt catgacccgc caccgggata acctgcattt
    13621 cagtaacaac aggcgtcgta aattgagaac tcatatttat gtcctttttc agaatcaatg
    13681 acggccgaaa acgggacgtt tacggtcaaa ggtccagccg gggatcaggt actgcatcgg
    13741 acctgcgtcg ttacgcgcac cgccaggcag acgtttatag gcctcatgtg ccttttgtac
    13801 ctgttcccag tccagttcca cgcccagacc gggcgcatca ggaacggcaa tttttccgtt
    13861 tttaatctcc agcggatttt gggtcaggcg acaatcgccc tcctgccaaa tccagtgggt
    13921 atcgatagcg gtaggattac ccggtgccgc cgcgcccaca tgggtaaaca tcgccagaga
    13981 gatatcgaaa tggttattag aatggcagcc ccaggtcagc ccccagtcgt cgcaaagctg
    14041 cgccacacgg actgcaccgg aaagcgtcca gaagtgcgga tcggcaagtg gaatatctac
    14101 cgcattgagc atcaccgcat gacccatttc gcgccagttg gtggcgatca tgttagtcgc
    14161 gacgggcaag ccggtcgccc gtcgaaattc cgccatcact tcacgtccgg agaagccctg
    14221 ttctgcgccg catggatctt cggcataggt aagaacatca ttcagccctt tgcataaaga
    14281 aatggcttca tcaagcagcc atgcaccgtt gggatcaacg gtaatccgcg catccgggaa
    14341 gcgtttcttc aatgcacgaa cagtgtcgat ttcttgctcg ccaggtaaca cgccgccctt
    14401 aagtttgaaa tctttaaagc cgtagcgatc ctgtgaggct tccgccagac gcacaacggc
    14461 ttcgctgttc attgctttct gatgccgcaa ctgataccac tcatggttgc ccggcgtatt
    14521 ttccacataa ggaagatcgg ttttggtccg atcaccgata taaaacagat aaccgaggac
    14581 ggtaatagcc tcgcgttgct tgcctggccc taacagttcg cagaccggaa cattcagcgc
    14641 cttacctagc aggtcaagca aagcggcttc cagcgccgcc acggcgttaa cgcgtaattc
    14701 aaaggtccag gcacctttac cgaaggtatc aaaatcggcg gcctgattac ctttatgcac
    14761 ctgctggacc actttattca gtcgcgcaac ttcctggccc agaaccatcg gaatagcatc
    14821 gacaagcgtc tgataaatca catctccgcc cggcgcttca ccaatgccgg tatgcccggc
    14881 gttatcggtg agtaccacaa tattgcgggt gaaatatgcg ttatgtgccc caccaatatt
    14941 aagcaacatg ctgtcatgcc cggccaccgg aatgactttc atatcagtaa taacaggact
    15001 ggattgtgtc gccatcttat tgccccgcaa caggtttcaa ctcgatacgc ttgatatcgc
    15061 ccaccagcac caggtagctc agtaccgcga ttaaggcatg aacaccaaca taaatcagcg
    15121 ccccattaaa cgagccagtc gtgccaacga tataaccaat tgcgattggc gtgacgatgc
    15181 cagaaatgtt accgaacatg ttgaacaggc caccggaaag accgctgatc tcttttggcg
    15241 cggtatctgc cattactgcc caacccagcg ccccgatgcc cttaccgaag aaggccagcg
    15301 ccataaagcc gatgatcatc cactcaacgt tgacgtagtt gcagaacacc atcaccatcg
    15361 acagcaacat gcccattacg atcggtgttt tacgcgcaat gttcagcgat cccgtgcggc
    15421 gcatcagcca gtcggaaata atcccaccca gcacaccgcc gataaaaccg caaaccgccg
    15481 gaacggaagc cacaaagccc gctttcagaa tcgacatccc gcgtgcctgc accagataaa
    15541 ccgggaacca ggtaataaag aagtaagtca gggcgttgat acagtactga ccgatataaa
    15601 cgccgatcat catccgtgac cctagcagct gtttgatctg cccccacttc acgctgaacg
    15661 gcactttaac tttggtgttt tgctgatcca tattgatcag cgcaccaccc gcggcgatgt
    15721 actccagctc tttcttattt acccccggat gttgatttgg ctcgtggatg actttcaacc
    15781 agataaagct gatgacaatc cccagaccgc ccataaagaa gaagacgtgt gaccagccca
    15841 cttcatgcgt cagccagccc ataatcggcg cgaagatcac cgttgcgaag tattgagcgg
    15901 agttaaaaat cgacaccgcc gttccccttt cctgcgccgg aaaccaggcc gcaacaatgc
    15961 gactgttgcc ggggaaagat ggcgcttcag caagcccgac caggaagcgc agcgtaaaca
    16021 gggcaacgat aatgccgaat ccactaaaga tatcgacgaa gccttgcagc aaggtaaaca
    16081 tcgaccagat aaagatcgac cagaagtaga cgcgttttga accaaaacgg tccagcaacc
    16141 agccaccagg gatctgcccg ataacataag cccatgagaa agcagagaac acatagccca
    16201 ttcccacggg atcaaggccg atatctttgg ccatttccga accggcgata gagagcgtag
    16261 cgcggtcgcc gtagttgaag gatgtgacga taaacaacat caccactatc cagtaacgag
    16321 catttgtgcg tttttccaca ctgctcgcag cctgacttaa agaactcatt gttgcactcc
    16381 tgaaaattcg cgttagccac gctcactctg gactgcgaca tcgccaggaa atcagaggtg
    16441 acgtagggtg ttttttgccg tttttatagg tcgttcgccg aatacggcgc gtgtttatat
    16501 ctggcaatag cagtataaaa agcgcgccat agcggctcac cgtgcaacaa cacaacatta
    16561 atgcgttcaa tgaggcccga ttttggcatt agccctggac ggtggaatcc acttcacgga
    16621 aatgaaaaca agaacaagaa aggaagggtt aaaacgaaga aataaagaag agtatgaaat
    16681 ggatcgcttg actccaggca aacgccagta aaaatccgcg ctatgaagca gtttttactg
    16741 gcatttgcct gaaaagattc gattcagcac cgctaaaacg acatttaccg ctcgctgaac
    16801 atatcaggac aacagcgtgc cccactgttc gacccacgga tttgattccg tttccggttc
    16861 cgggttctca ctggcgtcaa tcaacagcat ttcgccaacc cgctgagcgc tctgttcctg
    16921 caacaaggca tcgaactgtt tgccgccatt gcagaaattc acataactac tgtcgccgag
    16981 cgcaatcacg ccataacgca gattcggctg gaagcccaga ctatctttga ttccctgaaa
    17041 gagtggcaca atgctatcag gaaggtcgcc ctgcccggtc gtggacgtaa ccaccagaac
    17101 atacttatcc tgatagggca gccagtcgct taattcagga tcttcaaata ccgttgcttt
    17161 gtggccctgc gcggtcagaa tcgcttccgc ttcttcggcc actaacagtg aattcccgta
    17221 catggtgccg acaaaaatac caatttccgc cataccgttt tctccctgga ttaggaactt
    17281 atctctccat cctgacccga tggcgcactg aactcaaccc tttcattttc aggaagcaga
    17341 ccgcgccagc caaattgtga taacgcctgc atccaggtgt cgtccaggcc cgcgtgaata
    17401 gtcagcggct cgccagtaaa aggatgcgtc aatgacaact gactggcatg tagcattaac
    17461 cgctggaggc caaaatgctc agcaccgctg cgattctggc gtaaatcgcc atgtttgcta
    17521 tcgccaataa tcggatgacg caaatgggca agatgtcggc gaagctgatg tttgcgtccg
    17581 gttttcggct ccagttccac caggccgtag cgcgtggtcg ggtaacgtcc ggtcgctacc
    17641 ggcatttcta cggtcgccag accgcgataa tgcgtcactg ctggctgcgg gcctttatct
    17701 tcgcgggcaa atttatcagc gattttgtcc agttcttcca ccagtggata atccagcacc
    17761 gcttcttcca tcaaccagcc gcgcacaatc gcatggtaac gtttctggat ttggtgctgt
    17821 tcaaactgtt gtgccagcag ccgtccggcc tcgctggata atcccatcaa caacacacca
    17881 gaagtgggtc ggtccagacg atgagcagta aaaacatgct ggcctatctg gtcacgcacg
    17941 gtttgcatga ccactacttt ctcgtcgcga tccagccagc tgcggtgaac cagccagccg
    18001 gagggtttat ttaccgcaac cagccattca tcctgataga gtatttccag cattagctcg
    18061 catcatccgc aaaaagagca tccagttttt ccagctcagc cagaataagc gcgcgttgcg
    18121 gatggtccgt cgccagcgcc atttcataat agggtgcaac ggcaaaagcg cccggtaacg
    18181 gctgtttgtt atctaacaaa tcgtgcattc gcgggatcag cacccactgc aaccactcca
    18241 gtggttccat ggtgtccata aagaacggtt gggtactatt aaattgatgc ggctggggtt
    18301 catcgtttcg ccagtgctga tgttcacgca gtaacgcttc aagcgcctgc aactggagac
    18361 gaacgcggtc atgagtggtc ataaagcaac ctcaataaga aaaactgccg cgaaggatag
    18421 caggaataaa aaaagggagc actgtattca cagcgctccc ggttcgtttc gcagcattcc
    18481 agctactttt gttgctccct gctcatcctt gacaactttt cctctggcct tgcggccaat
    18541 cgttcatcct gaactattgc ttcctgctca caccaccccg atgtgatact tcatcctgaa
    18601 gtgtccctgg ccttcctgac ccaccgaatc atcctgaccg gttctcattc tccatcctgg
    18661 aggtgtcctt taacgcgtcc tgcgtcatcc tcttcgcttc atccagaagc ctttccctga
    18721 aacaccatcc tggtgtgtcc tgcagaagtg tcatcatcct gatgttcact tcgttgtctg
    18781 actccctgtc gacgaagata gaatcgtctt tttcgcgaag tcttacaagg cgcttacaga
    18841 caatgcctta aggaaaattt catatgaaag ttaagaatta acaatcaaca ttttgatttt
    18901 aaatgaaaat aacgattctt atctttttaa gtattcgctt atttcctggc gatctcctac
    18961 agagtctgta agagatctct cacaaccaga tggggtattt ggattacaga agaggcttaa
    19021 gttgattaag gaattccgca agatttgagg ctaaatgcgt ccgtttacgt gttcccagcg
    19081 tctctttgca cacttcaccg gagagattac acaccgagat gacctctaac tcttcttcca
    19141 gcgtcgcgat aaatagtgtg ggcggcagtt ttagcctttt ctgagtcacc agatgaccaa
    19201 tcagattttc ctgcacccga cggaagtcgt cttcactcca ggtttgcagc aatgtcagtt
    19261 tgatatcgcc aaactgcgcg tgcatatccc cggcaaactg agtcgtataa aaggtatgaa
    19321 ttgtgggttg tatcacaata tcaaaagcgc gttcaaccgc gtttacattt tgttccccgg
    19381 taaacggctg gggttgccag tatacggcat cttcggtagt tgaaataatg cacggtgaag
    19441 gaacaccgta cagttcctca cttaacggcc agcttttatg ctcttcatgc cacgcatcgc
    19501 agtagcgtgc agtaaaatct ttcagggctt gtgcggtcaa atcgtccact aatttctctc
    19561 ttcacttaaa ccagatacac ttgtcgttta gtttatctgg tttatgacgg tgaaacatgt
    19621 cttcttatgc aaaccatcag gcacttgcgg gcctgactct tggaaaatca accgattacc
    19681 gggataccta tgacgccagc ctactgcaag gcgttccacg cagcctgaat cgcgacccgc
    19741 tgggtctgaa agcggataac ctgccttttc acggtacgga tatctggacg ctgtatgaac
    19801 tttcctggct gaatgcgaaa ggtttgccgc aggtcgctgt cggtcatgtt gaacttgatt
    19861 acaccagcgt aaatctgatt gagtcgaaga gttttaagct ctatctcaac agttttaacc
    19921 agacgcgttt taataactgg gacgaggtgc gccagacgct ggagcgcgac ttaagcactt
    19981 gcgctcaggg taagattagc gtggcgttat atcgtcttga tgaactggaa ggccagccga
    20041 taggtcattt taatggcact tgcattgatg accaggatat cactatcgat aactatgaat
    20101 tcactactga ctatctggag aatgccacct gtggtgaaaa agtagtggaa gagacgcttg
    20161 tcagccacct gctgaaatca aactgcctga tcacccatca accagattgg ggttcgctcc
    20221 aaattcagta tcgtggacgc caaattgaca gagaaaaact gctgcgttac ctggtctcat
    20281 tccgtcatca caacgagttc cacgaacagt gcgtggaacg catctttaat gacctgttac
    20341 gcttctgcca gccagaaaaa ttgagcgttt acgcacgtta tacccgtcgt ggcggtctgg
    20401 acattaaccc gtggcgcagt aatagcgatt ttgtcccatc gaccacaaga ctggttcggc
    20461 aataaatttt ttctcaattt tgcgtgctgg attcacgcag aaggttgtga aaggtcatca
    20521 ggcagggcta ttgtaatcaa agggaatgac gatattcgtc ccataaggag tttttcttga
    20581 ttacacatat tagcccgctt ggctccatgg atatgttgtc gcagctggaa gtggatatgc
    20641 ttaaacgcac cgccagcagc gacctctatc aactgtttcg caactgttca cttgccgtac
    20701 tgaactccgg tagtttgacc gataacagca aagaattgct gtctcgtttt gaaaatttcg
    20761 atattaacgt cttgcgccgt gaacgcggcg taaagctgga actgattaat cccccggaag
    20821 aggcttttgt cgatgggcga attattcgcg ctttgcaggc caacttgttc gcggtcctgc
    20881 gtgacattct cttcgtttac gggcaaatcc ataacaccgt tcgttttccc aacctgaatc
    20941 tcgacaactc cgtccacatc actaacctgg tcttttccat cttgcgtaac gctcgcgcgc
    21001 tgcatgtggg tgaagcgcca aatatggtgg tctgctgggg cggtcactca attaacgaaa
    21061 acgagtattt gtatgcccgt cgcgtcggaa accagctggg cctgcgtgag ctgaatatct
    21121 gcaccggctg tggtccggga gcgatggaag cgccgatgaa aggtgctgcg gtcggacacg
    21181 cgcagcagcg ttacaaagac agtcgtttta ttggtatgac agagccgtcg attatcgccg
    21241 ctgaaccgcc taacccgctg gtcaacgaat tgatcatcat gccagatatc gaaaaacgtc
    21301 tggaagcgtt tgtccgtatc gctcacggta tcattatctt ccctggcggt gtgggtacgg
    21361 cagaagagtt gctctatttg ctgggaattt taatgaaccc ggccaacaaa gatcaggttt
    21421 taccattgat cctcaccggc ccgaaagaga gcgccgacta cttccgcgta ctggacgagt
    21481 ttgtcgtgca tacgctgggt gaaaacgcgc gccgccatta ccgcatcatc attgatgacg
    21541 ccgctgaagt cgctcgtcag atgaaaaaat cgatgccgct ggtgaaagaa aatcgccgtg
    21601 atacaggcga tgcctacagc tttaactggt caatgcgcat tgcgccagat ttgcaaatgc
    21661 cgtttgagcc gtctcacgag aatatggcta atctgaagct ttacccggat caacctgttg
    21721 aagtgctggc tgccgacctg cgccgtgcgt tctccggtat tgtggcgggt aacgtaaaag
    21781 aagtcggtat tcgcgccatt gaagagtttg gtccttacaa aatcaacggc gataaagaga
    21841 ttatgcgtcg tatggacgac ctgctacagg gttttgttgc ccagcatcgt atgaagttgc
    21901 caggctcagc ctacatccct tgctacgaaa tctgcacgta atctccgctc ccccggtgac
    21961 gtttgttgcc gggttttctc gtttttggtc acttactcat caactcattt catttgttat
    22021 atgaatgttt cttaccaccc tcacgcgaca aatatcatca cagttaatat gtcatacaat
    22081 ttatgttgca acgcaaacgt ttccctattt tcataaaccg tattttatcg ctatgaaaaa
    22141 gaaattatcg ccatgattaa ctaaaagtat tgattttttc agttcaacct acatatattg
    22201 cgcgccccgg aagaagtcag atgtcgttta atgggcaaat attgccctta aattctcttt
    22261 tacttttgat ttacagagta aagcgttggg ataatctatc ttccaagtag attattgtat
    22321 ttgagatcaa gatcactgat agatacataa cttgtgtgta tctttccgcc ctcaaattat
    22381 tacggcggta aatgattaag ccatcgccga tagacagatt tcatttttac ggtcaggcac
    22441 cttcccgggc tgaactggct aaaagctgaa ttatttgcat tcctccagga gaaatagatg
    22501 gaaacgactc aaaccagcac gattgcgtcg aaagactctc gtagtgcctg gcgcaagaca
    22561 gacaccatgt ggatgctggg cctttacggc acggcaatcg gcgcgggcgt gctgttcctg
    22621 ccaatcaacg ccggtgttgg cggtatgatc ccgctgatca tcatggctat ccttgcgttc
    22681 ccgatgacgt tttttgctca ccgcggcctg actcgcttcg tactgtctgg taaaaacccg
    22741 ggcgaagaca tcaccgaggt tgtagaagaa cactttggta ttggcgcagg taaactgatt
    22801 accctgctct acttcttcgc tatctacccg atcctgctgg tttatagcgt ggcaatcacc
    22861 aataccgttg aaagcttcat gtctcaccag ctgggtatga cgccaccgcc gcgtgcgatt
    22921 ctgtcgctga tcctgatcgt gggtatgatg accatcgttc gcttcggtga gcagatgatc
    22981 gttaaagcga tgagtattct ggtattcccg tttgttggcg tactgatgct gctggctctg
    23041 tacctgatcc cgcagtggaa cggcgctgca ctggaaacgc tgtctctgga cactgcatct
    23101 gcaaccggaa acggtctgtg gatgaccctg tggctggcaa ttccggtaat ggtgttctcg
    23161 ttcaaccact ctccgatcat ctcttctttc gccgttgcga agcgtgaaga gtacggcgat
    23221 atggcagaac agaaatgctc gaagatcctg gcattcgcac acatcatgat ggtgctgacc
    23281 gtaatgttct tcgtcttcag ctgtgtactg agcctgactc cggcagacct ggctgcggct
    23341 aaagagcaga acatctcgat tctgtcttac ctggctaacc actttaacgc accggttatc
    23401 gcgtggatgg ctccgattat cgcgattatc gctatcacca aatccttcct cggtcactac
    23461 ctgggcgcac gtgaaggctt caacggtatg gtgattaaat ctctgcgtgg taaaggtaag
    23521 tctatcgaaa tcaacaagct gaaccgtatc actgcgctgt tcatgctggt aacgacctgg
    23581 attgttgcca ccctgaaccc gagcatcctg ggtatgattg aaaccctggg cggtccaatc
    23641 atcgcgatga tcctgttcct gatgccgatg tacgcaattc agaaagtacc ggcaatgcgt
    23701 aagtacagcg gtcacatcag caacgtattc gttgtcgtga tgggtctgat tgcaatctcc
    23761 gcaatcttct actctctgtt cagctaagtc ctttcgcgcc gctttcgggc ggcgcttcct
    23821 ccgttttaac gcgatgtatt tcctatgatt agcgtattcg atattttcaa aatcggcatt
    23881 ggcccttcca gttctcatac cgttggacca atgaaagcgg gtaaacaatt taccgacgat
    23941 ctgattgccc gtaacctgct taaagacgtg acccgcgtgg tggttgacgt gtacggctcg
    24001 ctctctctga ccggtaaagg ccaccacact gatatcgcca ttattatggg cctggcgggt
    24061 aacctgccgg ataccgtgga tatcgattcc atccccagtt ttattcagga tgtgaatact
    24121 catggtcgcc tgatgctggc aaacggtcag catgaagtgg agttcccggt tgatcagtgc
    24181 atgaacttcc acgccgacaa cctttctctg catgaaaacg gtatgcgcat taccgcgctg
    24241 gcgggcgata aagtcgttta cagccagact tactactcta ttggcggtgg ctttatcgtt
    24301 gatgaagagc attttggcca gcaggatagc gcaccggttg aagttcctta tccgtacagt
    24361 tcagcagccg atctgcaaaa acattgtcag gaaaccgggc tgtcactctc tggcctgatg
    24421 atgaaaaacg agctggcgct gcacagcaaa gaagagctgg aacagcacct ggcgaacgtc
    24481 tgggaagtca tgcgcggcgg tattgagcgc ggtatttcca ccgaaggcgt gttgcctggc
    24541 aaactgcgcg ttccacgccg tgctgcggca ctacgccgga tgctggtcag ccaggataaa
    24601 accaccactg acccgatggc ggttgttgac tggatcaaca tgtttgcact ggcagtgaac
    24661 gaagagaacg ctgctggcgg tcgcgtggtg actgcgccga ctaacggtgc gtgcgggatt
    24721 atcccggcag ttctggcgta ctacgacaag tttatccgcg aagtgaacgc taactcactg
    24781 gctcgttacc tgctggtagc cagcgccatt ggttctcttt ataagatgaa cgcgtcgatt
    24841 tctggtgctg aagtgggttg ccagggtgaa gttggcgtgg cgtgctcaat ggcggcggct
    24901 ggtctggcag aactattagg cgcaagcccg gcgcaggtgt gcatcgcggc ggaaatcgcc
    24961 atggagcaca acctcggtct gacgtgtgac ccggtcgccg gacaggtaca ggtgccatgc
    25021 atcgagcgta acgccattgc ggcagtaaaa gcggtgaacg ccgcacgtat ggcgctgcgc
    25081 cgtaccagcg agccgcgcgt ctgcctcgat aaagttatcg aaaccatgta cgaaacaggt
    25141 aaagatatga acgccaagta ccgcgaaacc tctcgcggcg gcctggcaat gaagatcgtt
    25201 gcctgcgatt aatcgctctc cagaggcctc gttttgcgag gcctcttccc gatttctcat
    25261 ccagccgtag cctgttccgg catcgaatgt tacccttatc gcctgatctt taagggggtt
    25321 atcgtggctg ttcatttgct tattgtcgat gcactgaatc ttattcgtcg cattcatgcc
    25381 gttcaggggt cgccctgtgt cgaaacctgc cagcatgcgc tcgatcagct cattatgcac
    25441 agccagccaa cccacgcggt cgccgttttt gatgatgaaa accgcagtag cggctggcgt
    25501 catcagcgtt taccagatta caaagcgggt cgaccgccaa tgccggaaga gttgcacgac
    25561 gagatgcctg cattacgcgc cgcctttgag caacgcggcg tcccgtgctg gtcaaccagc
    25621 ggcaacgaag ccgatgactt agccgccacg ctggcggtca aagtgacaca ggccgggcat
    25681 caggcaacga ttgtttcgac agataaaggc tactgtcagt tactttcacc gacattacgt
    25741 attcgtgatt acttccagaa acgttggctg gatgcgccat ttatcgataa agaatttggc
    25801 gttcaaccgc agcagttgcc cgattactgg ggacttgcgg ggatcagcag ttcaaaggta
    25861 ccgggtgttg cgggaatcgg accaaaaagc gccacgcagc tgctggtcga gtttcagagt
    25921 ctggaaggga tatatgagaa tctggatgcg gttgccgaaa agtggcgcaa aaaattagaa
    25981 acccataaag agatggcgtt tctgtgccgc gatattgccc gcttacaaac cgatttgcat
    26041 atcgacggca atttacagca attgcggttg gtacggtaac ggcgagccgg atacgccgca
    26101 aacgtcgtat ccggcattat cacatcagcg catttaccag gcggtatggt aaagctctac
    26161 aatatcctca agcgttgctt cacgcgggtt gccaccggta caaacatcat ccagtgccgc
    26221 ctgcgccagt gccggaatgt cttccttgcg tacaccaaca tcacgcaaat gtggcggaat
    26281 accgacatca cggttgagag caaacaccgc ttcaacagcg gcattacgcg cctcttccag
    26341 gctcatacct tccactttca cgcccataac gcgcgcgata tcgcggtact tctcaccggt
    26401 aaagtcagcg ttataacgca tgacatgcgg taacaggatg gcgttcgcaa caccgtgtgg
    26461 agtgttataa aacgcgccca gtggatgcgc cataccatgc accaacccta acccaacatt
    26521 cgagaagccc atacccgcaa catactgccc gagcgccatt tcttctccgg catccttatc
    26581 accagcaacc gatcctcgca gcgccccagc aatgatttca atcgctttaa tgtgcagtgc
    26641 atcggttagc gcccacgcgc cacgggtaat atacccctca atagcatgag tgagcgcatc
    26701 gacacccgtc gcagctttca gcgctggagg cataccatcc atcatgtcag cgtcaataaa
    26761 cgccacctgc gggatatcat gcggatcaac gcaaacaaac ttgcgccgtt tctcttcgtc
    26821 agtgatcacg tagttaatgg tcacttctgc cgcagtacct gctgtggtag gaattgccag
    26881 aatcggtaca ctgggtttat tggtcgggga aagcccttcc aggctacgca catcggcaaa
    26941 ctccgggttg ttgctgataa tgccaatcgc tttacaagta tcctgtggag aaccaccacc
    27001 aatagcgatc aggtaatccg cgccgctatt ctggaataca ccgagccctt ctttgacgac
    27061 agtaattgtt gggttgggca ctacgccgtc gtaaatcgcc catgccagcc ctgcagcatc
    27121 catcttatcg gtcactttcg ccaccacgcc gcattgcacc agcgttttat cggtgacgat
    27181 cagcgccttc tgataaccac ggcgtttcac ctcatcggtt aaagccccaa cagcaccccg
    27241 accaaaccat gccgtttcgt tcagaatcat tctgttagcc atcatccttc tccttgttgc
    27301 tttacgaaat tactcttcaa ttcgtaaccc ataggttttg aatttctcca gcactacggc
    27361 aatctcttca tcgctcagca ctggcaccgg gtccgtaatc gccagggtcg tcaggtaaag
    27421 ttgcgccagc acttcaactt catgcgccag ccataacgct ttttccagat tcacctcaca
    27481 agcgataagc ccatgatgtt gtaacaaagt tgccttacga tttttgagag ccagcgcaac
    27541 atgttcagaa agttcgcgtg ttccaaaggt cgcataaggc gcgcaaggaa tagaattacc
    27601 gccagccgcc gcaatcatgt agtgaatagc ggggatcgat cggttaagaa tggaaactgc
    27661 cgtgcaatga acggcatgat tgtgaacaac cgcgttggca tccggtctgc tttgataggc
    27721 tgccatatgg aaacgccatt cgcttgaggg gagctttcct tcctcatgtt taccgttgcc
    27781 atcaataaag acaatatgcg actccgtcag tttttcatat ggaatgcctg taggcgtaat
    27841 cagcatccca tcctgataac gtacactgac gttccccgct gtcccctggt tcagtcccag
    27901 gcgggtcatt tccaggcaag tgtcaataat ctgacgagca agtttatttc gttccattag
    27961 ctacctctct ctgattcaaa acagggcaat aatgttgttc ctttcacact attgaattag
    28021 ccgtttaatt acccaccatc ttcttcctga ttaacaagaa agaaattcac aagcttatat
    28081 tttgtgacct ggttcaacta atcacagtaa ataactgcaa gttctctttt tataacccca
    28141 ttaaaaatga ccgctcttaa aaatatttat caaaacggtc atttttctat tcctccaagc
    28201 ccggaatgac cgttttcggc acaaacaatt aatacggtca tctgatttgt gttttttatg
    28261 atttattttc tgaaacgggc atgaaatttc gattattaaa gtgatggtag tcacataaag
    28321 tcaccttcta gctaataagt gtgaccgccg tcatattaca gagcgttttt tatttgaaaa
    28381 tgaatccatg agttcatttc agacaggcaa atattcactg atatgaagcc cgaactcgct
    28441 ggttttgcac ttttgaaaac ataaccgatt acgtgcttaa gcttctgaac ctaagaggat
    28501 gctatgggaa acacatcaat acaaacgcag agttaccgtg cggtagataa agatgcaggg
    28561 caaagcagaa gttacattat tccattcgcg ctgctgtgct cactgttttt tctttgggcg
    28621 gtagccaata accttaacga cattttatta cctcaattcc agcaggcttt tacgctgaca
    28681 aatttccagg ctggcctgat ccaatcggcc ttttactttg gttatttcat tatcccaatc
    28741 cctgctggga tattgatgaa aaaactcagt tataaagcag ggattattac cgggttattt
    28801 ttatatgcct tgggtgctgc attattctgg cccgccgcag aaataatgaa ctacacctta
    28861 tttttagttg gcctatttat tattgcagcc ggattaggtt gtctggaaac tgccgcaaac
    28921 ccttttgtta cggtattagg gccggaaagt agtggtcact tccgcttaaa tcttgcgcaa
    28981 acatttaact cgtttggcgc aattatcgcg gttgtctttg ggcaaagtct tattttgtct
    29041 aacgtgccac atcaatcgca agacgttctc gataaaatgt ctccagagca attgagtgcg
    29101 tataaacaca gcctggtatt atcggtacag acaccttata tgatcatcgt ggctatcgtg
    29161 ttactggtcg ccctgctgat catgctgacg aaattcccgg cattgcagag tgataatcac
    29221 agtgacgcca aacaaggatc gttctccgca tcgctttctc gcctggcgcg tattcgccac
    29281 tggcgctggg cggtattagc gcaattctgc tatgtcggcg cacaaacggc ctgctggagc
    29341 tatttgattc gctacgctgt agaagaaatt ccaggtatga ctgcaggctt tgccgctaac
    29401 tatttaaccg gaaccatggt gtgcttcttt attggtcgtt tcaccggtac ctggctcatc
    29461 agtcgcttcg caccacacaa agtcctggcc gcctacgcat taatcgctat ggcactgtgc
    29521 ctgatctccg ccttcgctgg cggtcatgtg ggcttaatag ccctgacttt atgcagcgcc
    29581 tttatgtcga ttcagtaccc aacaatcttc tcgctgggca ttaagaatct cggccaggac
    29641 accaaatatg gttcgtcctt catcgttatg accattattg gcggcggtat tgtcactccg
    29701 gtcatgggtt ttgtcagtga cgcggcgggc aacatcccca ctgctgaact gatccccgca
    29761 ctctgcttcg cggtcatctt tatctttgcc cgtttccgtt ctcaaacggc aactaactga
    29821 acatattttc cgaataaagt gaggaatctg taatgaaaaa aatcagctta ccgaaaattg
    29881 gtatccgccc ggttattgac ggtcgtcgca tgggtgttcg tgagtcgctt gaagaacaaa
    29941 caatgaatat ggcgaaagct acggccgcac tgctgaccga gaaactgcgc catgcctgcg
    30001 gagctgccgt cgagtgtgtc atttccgata cctgtatcgc gggtatggct gaagccgctg
    30061 cttgcgaaga aaaattcagc agtcagaatg taggcctcac cattacggta acgccttgct
    30121 ggtgctatgg cagtgaaacc atcgacatgg atccaacccg cccgaaggcc atttggggct
    30181 ttaacggcac tgaacgcccc ggcgctgttt acctggcagc ggctctggca gctcacagcc
    30241 agaaaggcat cccagcattc tccatttacg gtcatgacgt tcaggatgcc gatgacacat
    30301 cgattcctgc cgatgttgaa gaaaaactgc tgcgctttgc ccgcgccggt ttggccgtcg
    30361 ccagcatgaa aggtaaaagc tatctgtcgc tgggcggcgt ttcgatgggt atcgccggtt
    30421 ccattgttga tcacaacttc tttgaatcct ggctgggaat gaaagtccag gcggtggata
    30481 tgaccgaact gcgtcgccgt atcgatcaga agatttacga cgaagccgaa ttggaaatgg
    30541 cactggcctg ggctgataaa aacttccgct atggcgaaga tgaaaataac aaacagtatc
    30601 aacgtaatgc cgagcaaagc cgcgcagttc tgcgcgaaag tttactgatg gcgatgtgta
    30661 tccgcgacat gatgcaaggc aacagcaaac tggccgatat tggtcgcgtg gaagaatcac
    30721 ttggctacaa cgccatcgct gcgggcttcc aggggcaacg tcactggacc gatcaatatc
    30781 ccaatggtga caccgccgaa gcgatcctca acagttcatt tgactggaat ggcgtgcgcg
    30841 aaccctttgt cgtggcgacc gaaaacgaca gtcttaacgg cgtggcaatg ctaatgggtc
    30901 accagctcac cggcaccgct caggtatttg ccgatgtgcg tacctactgg tcaccagaag
    30961 caattgagcg tgtaacgggg cataaactgg atggactggc agaacacggc atcatccatt
    31021 tgatcaactc cggttctgct gcgctggacg gttcctgtaa acaacgcgac agcgaaggta
    31081 acccgacgat gaagccacac tgggaaatct ctcagcaaga ggctgacgct tgcctcgccg
    31141 ctaccgaatg gtgcccggcg atccacgaat acttccgtgg cggcggttac tcttcccgct
    31201 tccttaccga aggcggcgtc ccgttcacca tgactcgtgt caacatcatc aaaggcctgg
    31261 gaccggtact gcaaatcgcg gaaggctgga gcgtggaatt gccgaaggat gtgcatgaca
    31321 tcctcaacaa acgcaccaac tcaacctggc caaccacctg gtttgcaccg cgcctcaccg
    31381 gtaaagggcc gtttacggat gtgtactcgg taatggcgaa ctggggcgct aaccatgggg
    31441 ttctgaccat cggccacgtt ggcgcagact ttatcactct cgcctccatg ctgcgtatcc
    31501 cggtatgtat gcacaacgtt gaagagacca aagtgtatcg tccttctgcc tgggctgcgc
    31561 acggcatgga tattgaaggc caggattacc gcgcttgcca gaactacggt ccgttgtaca
    31621 agcgttaata cattactccc tgatgtgatg cccggtcgct ccggctaccg ggcctgaaca
    31681 agcaagagtg gttagccgga taagcaatgt tatccggcta tattgcagga gcgattatga
    31741 aacaagaagt tatcctggta ctcgactgtg gcgcgaccaa tgtcagggcc atcgcggtta
    31801 atcggcaggg caaaattgtt gcccgcgcct caacgcctaa tgccagcgat atcgcgatgg
    31861 aaaacaacac ctggcaccag tggtctttag acgccatttt gcaacgcttt gctgattgct
    31921 gtcggcaaat caatagtgaa ctgactgaat gccacatccg cggtatcgcc gtcaccacct
    31981 ttggtgtgga tggcgctctg gtagataagc aaggcaatct gctctatccg attattagct
    32041 ggaaatgtcc gcgaacagca gcggttatgg acaatattga acggttaatc tccgcacagc
    32101 ggttgcaggc tatttctggc gtcggagcct ttagtttcaa tacgttatat aagttggtgt
    32161 ggttgaaaga aaatcatcca caactgctgg aacgcgcgca cgcctggctc tttatttcgt
    32221 cgctgattaa ccaccgttta accggcgaat tcactactga tatcacgatg gccggaacca
    32281 gccagatgct ggatatccag caacgcgatt tcagtccgca aattttacaa gccaccggta
    32341 ttccacgccg actcttccct cgtctggtgg aagcgggtga acagattggt acgctacaga
    32401 acagcgccgc agcaatgctc ggcttacccg ttggcatacc ggtgatttcc gcaggtcacg
    32461 atacccagtt cgcccttttt ggcgctggtg ctgaacaaaa tgaacccgtg ctctcttccg
    32521 gtacatggga aattttaatg gttcgcagcg cccaggttga tacttcgctg ttaagtcagt
    32581 acgccggttc cacctgcgaa ctggatagcc aggcagggtt gtataaccca ggtatgcaat
    32641 ggctggcatc cggcgtgctg gaatgggtga gaaaactgtt ctggacggct gaaacaccct
    32701 ggcaaatgtt gattgaagaa gctcgtctga tcgcgcctgg cgcggatggc gtaaaaatgc
    32761 agtgtgattt attgtcgtgt cagaacgctg gctggcaagg agtgacgctt aataccacgc
    32821 gggggcattt ctatcgcgcg gcgctggaag ggttaactgc gcaattacag cgcaatctac
    32881 agatgctgga aaaaatcggg cactttaagg cctctgaatt attgttagtc ggtggaggaa
    32941 gtcgcaacac attgtggaat cagattaaag ccaatatgct tgatattccg gtaaaagttc
    33001 tcgacgacgc cgaaacgacc gtcgcaggag ctgcgctgtt cggttggtat ggcgtagggg
    33061 aatttaacag cccggaagaa gcccgcgcac agattcatta tcagtaccgt tatttctacc
    33121 cgcaaactga acctgaattt atagaggaag tgtgaaatgc tgaaaacaat ttcgccgtta
    33181 atttctcccg aactattgaa agtgctggca gagatgggac atggagatga aattattttt
    33241 tccgatgctc actttcccgc ccattcgatg ggaccgcagg tgatccgcgc tgatggcctg
    33301 ttggtgagcg acttgctcca ggcgattatc ccgttatttg aactggacag ttatgcaccg
    33361 ccgctggtga tgatggcggc ggtagaaggt gacactctcg atcctgaagt agaacgacgt
    33421 taccgtaatg cgctttcact acaagccccg agtcctgaca tcatccgcat caatcgtttt
    33481 gcgttttatg aacgggcgca aaaagccttt gcgatcgtta tcacaggcga acgagcgaag
    33541 tacgggaata ttcttttaaa aaaaggggta acaccgtaat ctcataccgg tacgcccgca
    33601 tgacgcgggc ggttatcgaa tgatggggtg aaaaatatga aagcggcacg ccagcaagcg
    33661 atagtcgacc tgctgctgaa ccataccagc ctgaccacgg aagctctctc tgaacagcta
    33721 aaggtcagta aagaaaccat tcgtcgcgat ctcaatgaat tacagacgca gggtaaaatt
    33781 ctgcgcaatc atggacgcgc taaatatatc caccgtcaaa atcaagacag tggcgatccc
    33841 tttcacatca ggctgaaaag ccattatgcg cataaagcag atatcgcgcg cgaggcgctc
    33901 gcgtggattg aagaagggat ggtgatagcc ttagacgcca gttcaacttg ctggtatctg
    33961 gcacgccagt tgcctgacat caacattcag gtcttcacca atagccatcc gatttgccat
    34021 gaactcggta aacgcgaacg cattcaactg atcagttccg gcggcacact tgagcgcaaa
    34081 tatggctgtt acgtcaatcc ctcgctgatt tcccaactta aatcgctgga aatcgatctg
    34141 tttatttttt cttgtgaagg gatcgatagc agcggcgcac tgtgggactc caatgcgatc
    34201 aacgctgatt acaaatcgat gctattaaaa cgtgccgcgc aatcgttgtt attgattgat
    34261 aaaagtaaat ttaatcgttc aggggaagcc cgcatcgggc atctggatga ggtaacgcac
    34321 attatttctg atgagcgcca ggttgcaact tctttggtaa cagcctgacg gaaagggtag
    34381 caggccggag acgacgcccc ggccttgcct gttatcgctc gtcgcgacga ccacccaccg
    34441 cagcccagat gcggcggacg tgcaccgtca cttcttcgcg atcgtgatac aactgccgcg
    34501 cctgaatctg agcatttatg ccatgttcat caagctgtgc ctgaatatac gccagattgt
    34561 gtgacacttc ttcgtagcgt tttttcatcg gcagtttgag gttgaaaatg gtttcacggc
    34621 accagccatt aaccagccac tgcgccatca atgccgcaac tttcgccggt ttttcaacca
    34681 tatcgcatac catccaggag atattgctgc gcgtcggacg gaatttgaaa ccgtcttccc
    34741 gcagccacgt cacctgtccg gtatccatca gactttgcgc catcgggccg ttgtcgacgg
    34801 aataaaccca catgttgcgc ttcaccagtt ggtaggtcca gccgccaggg caagcgccta
    34861 aatccaccgc ccacatcccg ttcgccaggc gttcatccca ctcatccgca ggaataaaca
    34921 catgaaatgc ctcttccagt ttgagcgtgg aacgactcgg cgcatctgcc ggaaatttca
    34981 ggcgcggaat gcccatatag aacggcgaat tattgttgct gtatgagtaa ccggtatagc
    35041 agcagcctgg tgcaataaag aatacatgca caaccggacg cttcggcgtt tcatagttcg
    35101 ccagcacccc ggcatcgcgc aaggcagcgc gtagcggaac agtaaattta cggcagaatt
    35161 tcagtaactc tttgctttcg ttggtatcgg caacttcaac acgcagttca ccgcccttct
    35221 ctactacgcc ctgtaacatg ccgacaatgg gggtaatacg atcttctggc ggcaaatgct
    35281 gcaggagttc ccccaccaca aaccactggc gggcaaaaat taatgaactg aacggcagct
    35341 cacggattaa cttatcgcca tcatcaggtt gataacattc ataaatgaca taacccgcat
    35401 tctctttcac gcgggcaaaa ccgaaaattt cccgctggcc ggctttatcg gtaatttctg
    35461 cggcgcactc tttttcaaag cccggacggc acagcaatac aaccttattc atgacttacg
    35521 cccttgcgct ttaaacggat agcaccaact aacattaacg cccagcccgc gaggaagctc
    35581 acgccgccaa ccggagtgac aaacgcccac aaacgcagat gggacagcgc caggcaataa
    35641 aggctgccgc tgaacaacac cgtgcctaac gcgaggaaaa cgctactcca gtaaaaccag
    35701 atactgatgc gacgctgcat tgccaccgcc agacctaaga tcgccagcgt atgaaacgcc
    35761 tggtattcga ggccggtctg gatccagccc atctcaacgg cccccatggt tttacttaac
    35821 acatgcgcgc caaaagcgcc cagagccaca aaaatgaagc cgctaatggc ggcgaaaatc
    35881 agcataaaac ggctggtcat ggtcgtaccc tacgtaaatt attgttcata acgaaagcgg
    35941 aatttttctt gttcagcagc ggctttcgcc aggatccatt ggcgaaaggc ggctatttta
    36001 cccagttctg cctgactgtc atgacaaacc agataaaaag catttttact gaccagaaca
    36061 tcattaaacg ggcaaacaag acgtccggcc tcgatttcag attgcgccat cacgttattt
    36121 gccagcgcca ctccctgccc gtggatagcc gcttgcagca ccatggcgct atggctaaaa
    36181 attggccctt gctgaacgtt gatatgattt aaccccaact gtcgggtata tgtctgccag
    36241 tcacggcgcg aagcatcatg taataacgta tgtttagcca gatcttccgg tgtcttcaag
    36301 ggtttttcgc cagtcagcag tagcggcgaa cacaccggca ataaatattc ggcgtacagt
    36361 ttttccaccc gtagccccgg ccagttgccc cgaccataaa atatcgccac atcaacatca
    36421 tccgccagct tatcttcctg acgatcaacc gcctggattc gaacgtcaat tcccggataa
    36481 gctgaattaa agctggaaag tcgcggaacc aaccaatgaa tggcgaaact ggggagtaaa
    36541 ctgaccgtca acgccccctt ggcgctacgg gcctggagtt tacgcgtcgc ttcggttaat
    36601 tgcgaaaata tctctttgat atcgaggaaa tagctttgcc cttcctcggt cagcaggagt
    36661 gaacgattac ggcggcggaa cagttttagc cccaaaaaat cctcaagaga cttgatttga
    36721 tgacttactg cggcttgggt cacaaaaagc tcttctgctg cgcgagtgaa acttaaatgg
    36781 cgtgctgcgg catcaaaaac tcgtaaggca tttagcggtg gtaatcgttt agacatggct
    36841 attaaacttt gatgttaaat gaatttaaca attagatcac actatgtaac ctattagttt
    36901 ttttaatctg agccattata aattgtccgt tgagcttcta ccagcaaata cctatagtgg
    36961 cggcacttcc tgagccggaa cgaaaagttt tatcggaatg cgtgttctgg tgaacttttg
    37021 gcttacggtt gtgatgttgt gttgttgtgt ttgcaattgg tctgcgattc agaccatggt
    37081 agcaaagcta ccttttttca cttcctgtac atttaccctg tctgtccata gtgattaatg
    37141 tagcaccgcc taattgcggt gctttttttt accttgcgat cgcgaattac tgatccagtt
    37201 cgaccatctc tttcacgtca gtacggttga tctgctgttt gttgccatta gcgtctttat
    37261 acgaaatcat accggtatcg ttatcagtct gtggtttgcc gtcagagacg atggtacgtc
    37321 cgtcattggt gtgcatcaca tagttcgaac cggaacaggc gctcagggca aaagtcagca
    37381 tacaggcaga aataattgcg gcagtctttt tcatcatctt ctccttaaag cgattaataa
    37441 atcttaatag tattgattaa taggctaaaa ttaacgccta acactattca gcatatgtta
    37501 cttacgcggc ttcgccagga tatccagata attctgatgg ttagcactct ccttgtatca
    37561 aagtgaattt tgcgtcacga tcggtgcatc aagccgagga gtaccatgaa cgtttttaat
    37621 cccgcgcagt ttcgcgccca gtttcccgca ctacaggatg cgggcgtcta tctcgacagc
    37681 gccgcgaccg cgcttaaacc tgaagccgtg gttgaagcca cccaacagtt ttacagtctg
    37741 agcgccggaa acgtccatcg cagccagttt gccgaagccc aacgcctgac cgcgcgttat
    37801 gaagctgcac gagagaaagt ggcgcaatta ctgaatgcac cggatgataa aactatcgtc
    37861 tggacgcgcg gcaccactga atccatcaac atggtggcac aatgctatgc gcgtccgcgt
    37921 ctgcaaccgg gcgatgagat tattgtcagc gtggcagaac accacgccaa cctcgtcccc
    37981 tggctgatgg tcgcccaaca aactggagcc aaagtggtga aattgccgct taatgcgcag
    38041 cgactgccgg atgtcgattt gttgccagaa ctgattactc cccgtagtcg gattctggcg
    38101 ttgggtcaga tgtcgaacgt tactggcggt tgcccggatc tggcgcgagc gattaccttt
    38161 gctcattcag ccgggatggt ggtgatggtt gatggtgctc agggggcagt gcatttcccc
    38221 gcggatgttc agcaactgga tattgatttc tatgcttttt caggtcacaa actgtatggc
    38281 ccgacaggta tcggcgtgct gtatggtaaa tcagaactgc tggaggcgat gtcgccctgg
    38341 ctgggcggcg gcaaaatggt tcacgaagtg agttttgacg gcttcacgac tcaatctgcg
    38401 ccgtggaaac tggaagctgg aacgccaaat gtcgctggtg tcataggatt aagcgcggcg
    38461 ctggaatggc tggcagatta cgatatcaac caggccgaaa gctggagccg tagcttagca
    38521 acgctggcgg aagatgcgct ggcgaaacgt cccggctttc gttcattccg ctgccaggat
    38581 tccagcctgc tggcctttga ttttgctggc gttcatcata gcgatatggt gacgctgctg
    38641 gcggagtacg gtattgccct gcgggccggg cagcattgcg ctcagccgct actggcagaa
    38701 ttaggcgtaa ccggcacact gcgcgcctct tttgcgccat ataatacaaa gagtgatgtg
    38761 gatgcgctgg tgaatgccgt tgaccgcgcg ctggaattat tggtggatta atgacaaacc
    38821 cacaattcgc cggacatccg ttcggcacaa ccgtaaccgc agaaacgtta cgcaatacct
    38881 tcgcaccgtt gacgcaatgg gaagataaat atcgccagtt gatcatgctg gggaaacagc
    38941 ttccggcatt gccagacgag ttaaaagcgc aggctaaaga gattgccgga tgcgaaaacc
    39001 gcgtctggct gggatataca gtggctgaaa acggcaaaat gcatttcttt ggcgacagcg
    39061 aagggcgcat tgtgcgcggc ctgctggcgg tgttgttgac tgccgttgag gggaaaaccg
    39121 ccgccgagtt gcaggcacag tcaccactgg cattgtttga tgagctggga ttacgtgcgc
    39181 agcttagcgc ctcacgcagc caggggttaa atgcgttaag cgaggcgatt atcgctgcga
    39241 cgaagcaggt ttaagcacag aaccgggtcg gataagacgt tcgcgtctca tccgacctga
    39301 ttgtttaacc ctgacgcgcc gctttcgcca tcatcttctt cagcgcatga gaaaccgcaa
    39361 caaacccaaa ggtggcggtc accatcgttg ccgcgccaaa tccagatgca caatccatcc
    39421 gcttcggccc ttctgccgtg gctttcatcg cacacaccgt accgtctgac tgcgggtaca
    39481 ccagcgcttc agtagaaaac acgcaatcca cgccgagctt acctttactg tttttcacta
    39541 cgccaaaatc gcttttcagg cgctcgcgca acttcgccgc cagcgggtcc tgaatcgttt
    39601 tcgccagatc ggtaacctga atctgcgtcg gatcaatctg cccacccgcg ccaccggttg
    39661 tgaccagtgg gattttattg cgccgacaat aagcaatcag cgccgctttg ggccgtacac
    39721 tatcaatggc atcaatcacg tacgaataac ccacgctcat atactgcgct acgttatccg
    39781 gcgtcacgaa atcatccacc accgttacac ggcactccgg gttaatctgg cgaatacgct
    39841 ccgccataac ttccgctttt gccagcccaa cgttatcgcg cagggcatga atttgccgat
    39901 tggtattggt gacgcacaca tcatccatat cgataagcgt gattgcgcca atccccgtgc
    39961 gcgccagcgc ttccgccgcc caggaaccga caccaccgat accaaccaca caaatatgcg
    40021 cgtcagcaaa cagttgcaac gctttttcac catacagacg cgctgtgcca ccaaaacgct
    40081 gacgccatgc atcactaatt accacagaca tagcacctca gaattaaaaa gggcgaggtt
    40141 atccctcacc ctaaacgcat aaatgcctga tgcgctacgc ttatcaggcc tacataactc
    40201 ctgcaatatt ttggatttgc atgatttgta ggccggataa ggcgttcacg ccgcatccgg
    40261 catgaacaac gcgcacttag tcaataatca ggatgtgagg ttacccctca ccctgtcata
    40321 tccgtaaaaa cggcatacag aatatcacat cagccgctaa agacgttacc tgcgcccggg
    40381 gcggttttca gcacccagac acgtccatag tggttgtacc aacctgcgcg gtgtccggct
    40441 tccggcccga tcccttgata gatatcgaag tgttggcctt tgattgcacc accgacatcc
    40501 agcgccacca tcagacgcag ttcgtactga ccattaaatt tgccgttatt atccagcaac
    40561 ggcacttctg ccagcaaggt agtacctggc ggaataatgg aacgatcaga ggcaactgac
    40621 gcgcgaccaa ccagcggcac cgcacttgcc cctttcaccg gagcaaaaga ttgcggttta
    40681 aagaagacga aagacgggtt ctgttccagc agctcgcgaa cctcggcttc actgtgtgtt
    40741 tcgccccagt gacgaatcgc ctgcatcgac atatcttctt ttttcacttc gccacggtcg
    40801 atcagcacct taccaatgct gcgataggca tgaccgtttt tccctgcata gctgaaaaag
    40861 ttaagcggac tgccatcacc aaagtcgata tacccactac cctgcacatc cataatgaag
    40921 ttatccatca gggagttact gtaagcgaga atatatttat cactcaatgc ccccgcgtag
    40981 atctccgcac gagacggcag acgaccacgt tttggcggca tacggtaaat aggatactgg
    41041 aactcgccct ggcgggtatg gcgcgcctga attaccggcg tgtaataacc ggtaaactgc
    41101 acgttaccat agttgtcggc accttccatc tgccaggcat caatgccgaa ctggcgcata
    41161 ttgcgggtat caccgcctgc gcgcagccac tcttgcaccg cgttataaac attactctgg
    41221 ttgccataca gacgcggtga cgaattacgg atatggttaa tttgctcggc aaaatcaccg
    41281 gcgttaatcg gcgcgccaac ggcatctggc tggttcacca gagagaaagg ctgggtaaat
    41341 ttcccgtctt tatattgctg tccgcgatcg gttggtttgg aagagcaggc ggcaagcatt
    41401 gccacaaccg tgcccataag aaggtacttt acccaacgtc ctttcattgt tctcttcttc
    41461 aggttaaaaa ataaggcgca acgaagataa caaaccgccg cgtttaatga aatgagcagc
    41521 ctctccctga cgcaaatttt gcacaaaaaa taggctttag tgatttgttt ttgttcaaaa
    41581 tcatgccaaa tccgtgatcg gggtaaaaaa aaggttgcat gaaaacgcga gcggagtata
    41641 gtgcgcatcc acggacgcgg ggtggagcag cctggtagct cgtcgggctc ataacccgaa
    41701 ggtcgtcggt tcaaatccgg cccccgcaac caattattga acaccctaac gggtgttttt
    41761 ttgtttctgg tctcccataa aaaagcgcca ttcagcgcct ttttatcatc cccttctcgc
    41821 cagcgtcgcc ccatcggcaa aatacgcttt aatccccgca agaatagact ccgcaacttc
    41881 ctgctggaaa gtcgccgttt tcagtttacg ctcttcctca acgttactga taaacgccgt
    41941 ttcgaccaga atggagggaa tatctggtgc ctttagtacg gcaaacccgg cctgttcaac
    42001 ttgattttta tgcagcttgt tgattttacc gagcttattc agtaccgctt taccaaactt
    42061 caggctgtcg gcaatggtca gcgactgtac catatcgaac atggtgtggt cgacatagcg
    42121 gtcaccgctt ttgctcacgc caccaatcaa gtccgaggcg ttctgggttt gtgccagata
    42181 ttttgccgca gtactggttg cacctttggt tgagagcgca aacacagagg aaccgctcgg
    42241 ctgacgactg gtaaaggcgt cggcatggat agagacaaac aggtcagcac gctgtttctg
    42301 ggcttttgct acgcgcactt gcaatggaat gaagatgtct tcattgcgcg tcatgtacac
    42361 cttcatattg ccctctttct cgatcagaga gcgcaaacgg cgagctattt gcaataccac
    42421 atctttttcg cgcgttttgt atttccccac cgcaccggag tcttcgccac cgtggccagg
    42481 gtcaagcata atgacaatcg gacgatcgcg ccctgcttta cccggttgtg gaccactttg
    42541 cgctggcggc acctgctttt cgaggtcgcc tttgttgtaa tcctccagca gcgccagcag
    42601 cgggtcctgc atatcctgtg cattggccgg atagaggtcc atcaccagac gctctttaaa
    42661 cccggcgacc ggcgcaaggg caaacagctg cggttttacg ttttgcttta attcaaaaac
    42721 catccgtacg gtttgcgggt caaattgccc gacgcgcgcc gacttgatga acgggtcgtc
    42781 tgcacgaatt tgtgccgcca tccccttgag taccgagttc aggtttacat cttcgatatc
    42841 caccaccacg cgttcagggt tactcaacgc gaactgctta tatttcagct gacgatttga
    42901 ttccaccgtc acgcgggtgt agctggacgc aggccagacg cgcaccgcca cgacctggct
    42961 gaccgcagcc agactgacct gacttacgct caatagccac atggcacccg cgccttgcag
    43021 taaacgacga cggctgattg cagtgttgga tcctgacatg cctctcccga gcaaaagaaa
    43081 tctaagctgt gtaacaagta aacgactaat ttgaccggaa actttagcga aagacgcata
    43141 atctgtcatc taataaacgg taaacattct ttttatattc acggcattac tgataaaaaa
    43201 gtcgctctcg cataaaattt acacttgcac cctgcgaaaa aacagaataa aaatacacta
    43261 atttcgaata atcatgcaaa gaggtgtgcc gtggtaaagg aacgtaaaac cgagttggtc
    43321 gagggattcc gccattcggt tccctatatc aatacccacc ggggaaaaac gtttgtcatc
    43381 atgctcggcg gtgaagccat tgagcatgag aatttctcca gtatcgttaa tgatatcggg
    43441 ttgttgcaca gcctcggcat ccgtctggtg gtggtctatg gcgcacgtcc gcagatcgac
    43501 gcaaatctgg ctgcgcatca ccacgaaccg ctgtatcaca agaatatacg tgtgaccgac
    43561 gccaaaacac tggaactggt gaagcaggct gcgggaacat tgcaactgga tattactgct
    43621 cgcctgtcga tgagtctcaa taacacgccg ctgcagggcg cgcatatcaa cgtcgtcagt
    43681 ggcaatttta ttattgccca gccgctgggc gtcgatgacg gcgtggatta ctgccatagc
    43741 gggcgtatcc ggcggattga tgaagacgcg atccatcgtc aactggacag cggtgcaata
    43801 gtgctaatgg ggccggtcgc tgtttcagtc actggcgaga gctttaacct gacctcggaa
    43861 gagattgcca ctcaactggc catcaaactg aaagctgaaa agatgattgg tttttgctct
    43921 tcccagggcg tcactaatga cgacggtgat attgtctccg aacttttccc taacgaagcg
    43981 caagcgcggg tagaagccca ggaagagaaa ggcgattaca actccggtac ggtgcgcttt
    44041 ttgcgtggcg cagtgaaagc ctgccgcagc ggcgtgcgtc gctgtcattt aatcagttat
    44101 caggaagatg gcgcgctgtt gcaagagttg ttctcacgcg acggtatcgg tacgcagatt
    44161 gtgatggaaa gcgccgagca gattcgtcgc gcaacaatca acgatattgg cggtattctg
    44221 gagttgattc gcccactgga gcagcaaggt attctggtac gccgttctcg cgagcagctg
    44281 gagatggaaa tcgacaaatt caccattatt cagcgcgata acacgactat tgcctgcgcc
    44341 gcgctctatc cgttcccgga agagaagatt ggggaaatgg cctgtgtggc agttcacccg
    44401 gattaccgca gttcatcaag gggtgaagtt ctgctggaac gcattgccgc tcaggcgaag
    44461 cagagcggct taagcaaatt gtttgtgctg accacgcgca gtattcactg gttccaggaa
    44521 cgtggattta ccccagtgga tattgattta ctgcccgaga gcaaaaagca gttgtacaac
    44581 taccagcgta aatccaaagt gttgatggcg gatttagggt aagcgatgaa aatcgtcgga
    44641 tgcgacatgc gtaacactcg tacgtcgcat ccggcaatta cgtttattcc cgtgaactaa
    44701 acaacgccgc cagaccactg cgccgctcag tacgagtggc gattgccgca cttaatatgc
    44761 gctcatcggc atacagcgac agacggcgac gcgcgcgggt caccgcggta taaaccagct
    44821 ctcgcgttac taccggcgtg cgttggctcg gcaaaatcaa cgccgcatgg tcgaactccg
    44881 atccctgcga tttatgtacc gtcatcgccc acgtagtttc gtgctctggc aagcgactcg
    44941 gttgcacaga cttaatattg ccgtccggca tcgcaaacca gacgcgcgtc ccctgcccgc
    45001 gatccagcgc aataccgata tcgccattaa acaacccaag cgcgctgtca ttacgggcaa
    45061 tcatcaccgg tcgaccttcg taccaacgag agtgcggatg acgatgaatt ttgcgcttct
    45121 gttgcataaa ctgctcaatt cgctcattca gtccagccac gccaaacggc ccttcccgca
    45181 gggcgcacaa aagctggtac tcattgaacg cctgaatgat taaatccggc tcggcacgcg
    45241 cttgcagcag atccagataa cgtccgtaac ccgcaagagc ttcctcaagc atcgcaatat
    45301 aatcttcgcc gctctgtaaa agccgttttt cgatatcagt aaaatcctgc tgaaaaacgg
    45361 ttttcactgc cgttttatca ccacggttga tcgccgcagc taactgacca atgccagaat
    45421 cgctgccgaa acgatagctt ttttgcagca ggcagagact gtcgcgcaaa gatgccgctt
    45481 ctgtgccggt tcctgccgga acgtgagtcc ccgtcaggcg gcttagctgc ctggcacgct
    45541 cggcggtaaa gcccgcgttg gcataagcgc agatatcgcc cagcacagcc ccagcctcaa
    45601 ccgaggccag ttgatcacga tcgccgagaa agatcactcg cgcatgatcg ggcaaggcgt
    45661 cgatcagtct cgacatcata ggcagatcga tcattgacgc ttcatctacc accagcacat
    45721 caagatgcag cgggttaccg gcatgatgac gtaaacgctg gctacccggc tgcgcgccca
    45781 gcaatcggtg caaagtgctg gcatcttccg gaatgcgttt cttttgttca tcggtcagcg
    45841 gtaactgtcg caaagccttg ccgagagatt cggttaagcg cgcggcagct ttacccgttg
    45901 gtgcagccag acggatacgg cagcgttcgc cgtcggccat ttgaattaac gctgccagca
    45961 acttcgctac ggtggtcgtt ttaccggtgc cagggccgcc ggaaatcacc gagatccgcc
    46021 gcgtcagcgc cactgccgcc gcaacttttt gccagttaat ttcatcgctt actggaaaaa
    46081 gtttgtccag ggtttgcgcc agtagagctt catcaacctc aatggcatga ttcacttcgt
    46141 tgaaaaagcg tgccactgtg cgctcgttac accacatgcg attcaaataa agacgatcgc
    46201 cacagaggat catcggcgtg ggttcatctc ccctgctgac cgcttgagaa gccagcaagc
    46261 attcttccca attttgtagc tcaccgattt cactgacaca ggtcgccaac agcggatgcg
    46321 acgcctcgtt attttccagt cgtgaaagcg gcaaacaaac gtgtccctct ccggcatcat
    46381 gacttaacag tgccgccgcg agggtgacgg caggatgttc atctcccgcc acggtcaggg
    46441 caaattgcac atccagcggg cgtagctgtt tgtgctccac agcttccagt aattgctttt
    46501 gcaatttcat tacgcctcct ccagggtcat accggcaaac atctcatcca tcagggcaat
    46561 caacccggcg ttgggtcggg ttgtgtaaat cccctgttgc ggatgttctt tatcaacgcc
    46621 acgcaggaac agataaataa cgccgccaaa gtggtgctca tagtcgtaat cagcaatgcg
    46681 atggcgcaga taacgatgca gcgccagggt ataaagctga tattgcagat catagcggtg
    46741 tgcctgcatt gccgctgcca tagcctgttg ggtgtaagcc gaactgtctt cacccaacca
    46801 gttggattta tagtcgagca ggtaataacg cccttcgtgg cggaacacca ggtcgataaa
    46861 gccttttaac atgccacgta cctgcatgaa ctccagcggc gggcagcctg cggatagcgg
    46921 gtcaaactgg cggattaacg tatcaagctg actggcgata agcggttcac taatcggcag
    46981 ataaaactcc atctccacct gtttattgcg ggcggaaagt tgactcaggc ttacgccggt
    47041 ttcattgaga ggtgcctgga ggacagccgt gatccactcg gtcaataccg gttcccactg
    47101 cgattcaaag ccgccgagtt ccagtttttc ccgcacccag ttcgggtcaa ccggctgggt
    47161 aaaatccagg tcttcaaaca aactgtgcaa gaacgtcccc ggtgacgcac cgcgcggaaa
    47221 ctgatgtggt gttaacgtcg gttcttcaac gacgctggca acgcctgcag catcgacatc
    47281 cagccgaggc atcaaatcct gggcgatacc gtgaccacgc tgttgcaaac cagagtagct
    47341 ggtgacgcgc cagttatcgc cgggcaatcg ttgtaacgtc ttcgcattca gctctgctgt
    47401 agaaacatca ttaacctgcc agggttggtt atcaccagtt tgtgccgttt gccaggcaat
    47461 atcatcatcg cataacgctt caatacaggt gcgaagccct gccgcatctt gcggttcccc
    47521 tttttgcagc aaacgcccga gcgcactttg gtggacgtcg gtgtcacctt ttttatcgcc
    47581 acgacggcgc accagcggtg caacgccgag actgcaatgc caaaccgaac gtgtcagcgc
    47641 cacgtaaagc aaacgcagat cttccgccag acgttcggcc tccgcgaggt cgacgctttc
    47701 tggcgcagca ttaagatcca gaactgcctc aaacgagtgg cgatcgtgat aaaacgcctg
    47761 ctcctggacg cggaaattgg tgataaacgg cagccagacc aatggatatt ccagcccttt
    47821 cgatttgtgg atcgtgacaa tctgcaccag atgtttatca ctttcgagac gcatttgttg
    47881 gctggaggca ttactgtctg gctcgaggat atgttgcgat aaccagcgta ccagcgcatg
    47941 ttcactttcc agctgcgttc cggcttcttg tagcagttcg ctgatatgca agatatcggt
    48001 aagacgccgc tcaccgcctg ccgttgccag caagttttca gcaatgttac gcgccgacat
    48061 cagcgcccgc agcatcggca taacgccacg tttgcgccag atttgccgat aaccatcgaa
    48121 ctcttcgact accacatccc acgcatgttc gtcattgttc agcgtttcga tatccagcgc
    48181 gttcagcccc atcattgacg ttgccagcgc actacgcagg gtgttctcac gttcgggcgt
    48241 catcaccgcc tgcaacaacc aaagcatttc ctgcgcttcc agagtttcaa aaacactgtc
    48301 gcggttcgaa aggtaaacgg aagggatttc cagcaacgtt aaggcatcgc gcacctgggc
    48361 ggcctcctgg cggctgcgca ccagcacact gatgtccgaa gcacgcaccg gacgcgcgtc
    48421 gtcgccgttc atcagcaacg cttcgccccg ctgtccggct tgtagccagt cgcggatttg
    48481 cgcagcacat acctgcgcca tggtactttg ataatcgcca acgccgcagc tttcgccttc
    48541 catcagccac attttcatcg caggctgtgt ttcaccttta aatacaaaac gtaacgcctg
    48601 atttttcccg gctgatttca ctggaataaa cggtatttcg cgaaacatga acgcgtcatc
    48661 agtctggctg aaaagcttat tcacgctgtt caccattcct ggtgcggaac gccagttggt
    48721 gtctaaagtg tagtgggcgt gaacttcgct acgcgccttc atataagtga agatatccgc
    48781 accccggaat gcatatatgg cctgcttcgg gtcgccaatt agcaacaatg cggtttccgg
    48841 ctgatggtgc cagatacggc gaaaaattcg gtactgctgg gggtcggtat cctgaaattc
    48901 atcgatcatt gccaccggga atcgcgtacg gatcgccgct gccaacacct caccgctttc
    48961 gctacgcagc gcggaatcga gccgacttaa catgtcatca aaacccaatt cgccacggcg
    49021 gcgtttttca cgcgctactg tttcgcggat ctcagccaat gcgcgggtga tcaccagatc
    49081 gcggatcgac aatggttctg caagcagttg atcgatcgcc tcaaacagtg gatgtcgcgg
    49141 ggtttccccc ccggccttcg tgcgatcttc taagaaacgc tgggagaatt tttccagcga
    49201 ctccggcaac tgataactgt ttgtctcttc ttctgcccag gcgctgatct tgtcgatcca
    49261 tttagcctga ttgctacggt taaacttgcg tcgatcaata ccagaagatt cgatcagcgc
    49321 atccagttca cccactgcgt cgcgccactg ctgttttacc gtatcaatac gcgccacaat
    49381 ttgcgcgtga cgggaagcca gcgtttcatc atcgggcggc ggtgctttga taaccggcgc
    49441 ttcgccttgc agataacgat taatatcgcg cagcaacgcc tgcggccctt tccaggtttc
    49501 aaagacgacc tgggctattt cacgcggcag cgggtagcag tggcgacgcc agaaatcggc
    49561 gcaggcctgg tagcgtagca gagactcatc ttcaatcagc tgctgctcaa acagcatgcc
    49621 ggattcaaag gcattcaggt tgagcatgcg ctggcaaaag ccgtgaatag taaagactgc
    49681 cgcttcatcc atctgccgtt cggctaacaa caaccactgc gcggcttgcg ctttatcgtc
    49741 gatctcttcc agcaggcgtt cgtacagtgg attgtcggtg gtttcacgca gacaggcgat
    49801 gcgcaactcg tggatattgc tacggatacg accgcgcaat tctgccgtgg cagcctcggt
    49861 aaaggtgacc accagcagtt cttcaacggt cagcgggcgg ggaaaggcgg cggaaccgcc
    49921 tagtccaagt aacaggcgca aatagagcgc cgcaatcgta aaggttttgc ctgtgccggc
    49981 agaggcttca atcaggcgct caccctgtaa gggcaagcgc aaaggatcta gtgtctcggc
    50041 gacatcactc attcttttca ctcatcaggg gcattgtttg ctgcaacgcg ctgacgttct
    50101 cccacacttt ccagccttca gggtgtacat attcggcttt cccgttctgg ctgccggaaa
    50161 tctgcgacag aatagccatg ccttgcggct cgaccaccgc ctgatggaag aaatcagcaa
    50221 gtttttgcgg cgtcagcagt tttatctggg ccacgatttt atcacgcgaa tcgaagcgca
    50281 tattgccgcg atcgaaatct ttacttaact tcgatgcttc ttcgccgagc gtttgcggtg
    50341 cctgcagcat ctgggtaatt accgcctgct ggatttgcgc aaactcatct ggcttcatcg
    50401 ctcgcaattt tgcctctgcg gttgggaaaa acgccttgta acgctcccac aagaatgaag
    50461 gctgtttatc attgctttgc aaaaggaagc ccatgcccca ctgacgcccc acgctcattg
    50521 gaaacgcaaa cacggcatag cccaattgtt cttcggtacg caactgattg tagaaccacg
    50581 gctgtacgat ctgccccaac agagagctat aggctgagct ggtgtattca tcgtagccag
    50641 tcggtacaaa taccgctgcc agtgcggagt cggtgctgtt accggctttt tcaaagatga
    50701 cggattgttt tttatcgacc actacatctt tgtttcgaca ccactctgaa ccatcagcgc
    50761 ccaactgttt ttgcacatcg cgtgccagcg ttgttgcctg ggcctcggtc atgttgccga
    50821 taaccataaa ctctggtcga gcccctgatt ttaaggcgtc gcgataggcc agcacctctt
    50881 tcaacgtaat ggagggcaaa attttacgcc gttcatctcg cgagaagtac ggcacttgcg
    50941 agagcatctg cgcgggcata atcgcctgct caaacgcttt acccttttct gcggaatcca
    51001 tcatctggtt ataccaggac ttcgcctgct caagctgatc ttccgtagcg gtatagctaa
    51061 agtacccctc gagcaatgcc tggaacagct gcggcagacg ctgggtgtaa ccattagcat
    51121 taaccataag gccgttgtta gcgttggtgg aaaaacttat gccaccaacc gacgcctggt
    51181 tgcttaactg atcaagcgcc agccctgcga gataatcatt gagcgcaaac atcacctgat
    51241 tgcgggcgct gtccatggct ttcggattac gcaaaatcag gctgacatca gctttgggct
    51301 cgctggcaaa ataacggctt ggcgcataca ccacgcgcag attcgactca tcaacaatca
    51361 gctctggatg gtcgtatttc ttctctgact taatcagcga gaaatcatca ggaatataag
    51421 ggttaagctc tggcaaagag agcgcaatgt cggcggcttt tttctgccag tcggcgaaag
    51481 tttgtgcgct gattttatcg acctgatacg gcgcatcgac aaagtaagcc gttttgttgt
    51541 gcggctcttt cgggctgata taccagatac gcgcattctg cggcgtcatc atcgccagac
    51601 gttcctttac tgctttagca tcgtaccgat cggcaatatt gactgcatcc agcgtatgct
    51661 caacaggaac gcgaatcatg gtatctgcca gccattcgac gtaatccata tcacgggtga
    51721 tcgacggata acggaagtcg atatccagca cattcgccag ttcatcgaag tattgtttat
    51781 caatgccttt ttcacgtaac agattgagat agctaaaaat tgccgccaca acctgatcgc
    51841 gattagccag gcctttatcg gttaaagacg cagagatcgc taatacgccg ctgttgccgt
    51901 tgacgatagg atcggagttg gcgctaatgc cctcaactaa tccctgcttt tgcagccagt
    51961 cagaaagtgt acctgggctg cgattgccaa tcagataggt aatcaattca tcggttttac
    52021 tacggaactt cgctgagttg ttatcgatgc gaaactcaac gcgcaacact ttacgcggca
    52081 gcgcagggac gtaatgaatg ataatgccct tttgcgcgtc ggtgactacc ggcacggtga
    52141 tttccggttt tttgctctct ttgttcggca cgcgaccaaa ggtgtccgcc gccatttttg
    52201 ccaactccgg cagcggttta ttactgtaaa taaccgcctt catcaaattg gcggaatagt
    52261 acttctcgtg gaaatctttc agcgcctgct gcaccggatt accaggtttg tcgcttaaag
    52321 tttcgaggtt accaccagaa aactttgaac cggggtgtgc cgggttaatg gtttctgcgc
    52381 tgacctgtgc catgcgcatc ccgtcacgcg tacgcgccat ggttaattca gcgttcaccg
    52441 cattacgctc acgttcggca tatttcttgt cgagcaaagg ttcagcaata gcatcggcca
    52501 ggcggtctac cgcaccaggc aaggcgtcgt tctcaacttc cagatagaaa gccgtgcgat
    52561 acggcgcagt gctggcattg tgactaccgc cgtgcatttt gagatattcg gccagactgt
    52621 cagcctgcgg gtactttttc gaccccatca gactcatatg ttcaaggtaa tgtgccagcc
    52681 cctggtacgc ctcgggatct tccagcgacc caacgggcac caccagcgcc gagagcgatt
    52741 taactgcctg cggatcagaa accagcaaga ccaccatacc gttatccaga cgtatagcct
    52801 gatactggcg gttatcttta tcacttttac ggatggtttc ctgaatcggc tgccatcccg
    52861 tttctgcctg acttaagggt gcccaaaggg caactaacaa caataatgct ttgaaccaag
    52921 tgctgcgggg cattcacgga cctcataatc aacttaattt tctgtccaga ttcaacacgt
    52981 taacgcaaat catctgccag aatttaatct tgtgctgcac gagtcagcct atgtttatat
    53041 aaccatcagt ccgtgactgg tgcgcatcat aaagtaagcg gatagattgc gcaattttta
    53101 tacagcactc atgactgatt aaagcgaaac agcggtaaca ggaaacgttg cgactgttca
    53161 acgatggcct ccattgtctc tggtgttaat tgccgccaga gcctttgata ccagatatca
    53221 tcaccttcgc cacgcaccat catgttgcct tcgtaagcct gaaggaattt cgtacgggct
    53281 ttttgcaacg tggaatcgtc atccagcatg gcatcgtttt gcgcgtcata acaggttttt
    53341 agccacgcgc cgccactttc aggtaacacc agcaatggcg cggacattcc ttcacgatac
    53401 ccctcaatca gttgtgagag gtaatgcaaa gcctgttcgg ctgcaagcgg cggaaaacgc
    53461 cactcgccgt ctttgcgtag aaaaaggcga ctttcaccat taccaccgct ggcacagtag
    53521 acaaggtgtt ccagccaaag ttgcattccc tgggccacac ttaataaaga gggacgccag
    53581 cgcaacaggc catccggctg cacctgcggc aaccagccag ttatctgcac accgttgcag
    53641 gcgagatcaa tttccatact ctgccccggc tggcgacagg caatgactct gtcggcaagc
    53701 tgctgcatct cctggcactg tgtttcccag aaaatttcac caaaagcgcc atacggtaaa
    53761 tcccctgccg ctcggaagcg gcggaacaag cgttcggcat catcctgctc aaccagtgca
    53821 ttcaataact gctgattgat ttgataacgg ctaagtcctt ccagaataaa tggctcggtg
    53881 tcggggattt cgctgtcttc agtacggaag ttcacctgca aacgcatctg gaaaaatgcc
    53941 cgcaccggat gtgcccagaa tcgttgtagc gtttccagcg gcacggtttc cggtaaggta
    54001 aacggcagcg gctgaacaaa ttcagaatgt gctttaccag cctggctggc cgcaggtagc
    54061 cattcacgag catagctttg tcgttcgcct ggctggtagt tttgtggatc aaacggcatc
    54121 cgggtatgga ggcaagtaag atgcgctttt acccttgcct cgctttcatc acagttgagc
    54181 gcttcatcgc ccggtagata atgactttgc ccgatgtagt cgatcagttc ctgcaccagt
    54241 accgacggga aacgctcact gttatcctga atggaacgac cgatatagct gatatagagt
    54301 ttttgctgcg cggaaattaa cgcttccagg aacagatagc ggtcgtcatc gcgacggcta
    54361 cggtcgccac gcttcggttt ctggctcatc aggtcaaagc ccaatggcgc aagctgacgt
    54421 ggataaacgc cgtcgttcat tcccagcagg caaaccactt tgaacggaat tgaacgcatt
    54481 ggcatcagag tacaaatgtt aaccggtccg gcgagaaaac gctggctgat acgttcttga
    54541 tccagacgct gtgccagttc atcacgcaat agtgacagcg gcaccgcgtc gccatactgc
    54601 gcacctaaac cttcggcgat aatcgcctgc cattgttgtt cgatcagcgt catcgccgct
    54661 tcggtttccg catccggcag gaagaaggcg ttgagcatat cgcgacaaac cggcaaccac
    54721 tcttccagcg gacgctcctg tgccagcccg cgacgccaga tgtttagctg cattagcagt
    54781 gaagccagat gccccaccag ttctgcaatt aagccgctcg attcatcata aggtagaacc
    54841 gattgccact cgccctgcgc gctctccatc gcgtagccca acaacatacg cgtcaggcca
    54901 aatcgccagg tgtgttgtcc ggtggcgggg agttccagct cgcgaacgtt gtcgtcatct
    54961 atgccccaac gaatgccgga ttcgttgacc cactggcgta aataacgcag cccttcttcg
    55021 gtgatgtcaa accgcgccgc cagcaccggc acatccagca acgccagcac atcctctgac
    55081 acaaaacgac tgtcaggcag tgataacagg ctgataaacg cttccagtac cggatgtgac
    55141 tgccgcgcac gacggtcgga aatggcgtaa ggtaggtaac gatccgcagg tgcgctacca
    55201 aacacagcct gaataaacgg actgtagctg tcgatatcag ccaccatcac gatgatgtcg
    55261 cgcggagtaa gtgtcgggtc ttcctccagc atcgccagca ggcgatcgtg taaaacttca
    55321 acttcacgct gcgggctatg gcaaacgtgg aaggtgatac tgctatccag tggatcaagc
    55381 gggcgtttgt tatcgctacg ggaaaactct tcgatgttca caccagcaac ggcgcggttt
    55441 tccagttcca gaatgtcaga ctgaatgtta tgcagcaggt tatctggcgt gacatcgaca
    55501 aaggcgtcca gctcctggct gctctccagg tcagaaagga gataaatgta gtcgcgccca
    55561 agcttacccc atgaagccag cagcgggttg ccgacatcct gttcaccatc gctgttaaag
    55621 agctgcccgg cattttcgct atcacgaaat agcggcaatt cgcgatcttc aaaactgtgt
    55681 cgacgctgac gggtcagcag tttcgccaga taagcaggat ctttaatatc gccccagtaa
    55741 taacggcagg ggttggtaaa caggagatgg atttcaatat gtttacccag cgcctgtagc
    55801 gcctggagat aaacaggcgg taacgcggaa ataccgcata taaagacgcg cgaaggtaac
    55861 cccggcgggc aggtcgtcgc ggactccagc gtttcgataa agcgctgata gagattggcg
    55921 cggtgccagc gcggttgccc gagttgatgg gtatattcca ccagcgcctt ccacaacggg
    55981 gcttgccagg cctgtgcttc tcccagccct tcaaccaaat gtcctgtttc ccactgtgcc
    56041 agccagtccg gacgatagac cagatactgg tcaaacaggt ccgccgcttt tgaggaaagc
    56101 tggaacagtt ttcgcttgtc gctatcgtca gtcagataat gccgcaacag ggtaaagtct
    56161 tcgcgctcca gcaattgcgg cagcagagtc atcagtttcc agctcatgct ctgtttgtta
    56221 aaggcgctct ctttggggat ttccggtaac acccggacga acatatccca gataaagctc
    56281 gctggcagcg gaaaatcaat gtttgccgca ataccaaact tttgcgacag ggtcatttgc
    56341 agccactgtg ccataccggt actttgcacc agaatcatct ctggttcgaa aggatcgtcc
    56401 agccgttcgc gttcgacaat aaactccatc aacgcttcca gcacgtccag acgattggaa
    56461 tggtagaccc ttaacatagc ggctcctgac tactgacgat tcgggcaatg caggcgggtc
    56521 atctcgcctt ctctgccccc gggtgaaact agcgtaacgc tgatgctgac acatcccgcc
    56581 tgcgatgtct gcattcggtt gacctgccag ttggcaggtg gcgaaatcgc gcgcagttgc
    56641 gtttgctgcc agccatgccg ccagagctgt tggtactggt ttctgctggc aagactgttc
    56701 attaatgttc gctggaaacc cgataacgca gtgacaatca tcaccatcaa caccatcgcc
    56761 aacattacct ccggcaggct aaagccttgt tgattcttca gggaagctga cataacgccc
    56821 tctctttcag cggacaaaaa tcgctccagc cgcgtggcga aaaaacaatg tttccatcaa
    56881 tgacttcgcc tgttcgccac aacgaaacgc cttcataacc ggcaatcaat aaggcttcat
    56941 tatctgccag taaacgcaaa caaacctggg catcggtttc agcgtactgc gagcactgaa
    57001 ctgctggctg cgtctgccag gagtgcattt ttccccacgc cagcgccgac tgaacgatgg
    57061 cctggcggcg caatgactga ctttccatgc tcacgcgaga ggcaaaactg cgatcctgtt
    57121 ggctcattcc ttgtaatagc aaactaccca aaaccagcag catcaggacc agagccagtg
    57181 acgaaacacc cttttcgcgg ttcacaggtt gaatcctgtc acgctatagc tggcattcac
    57241 cacggtttgc ggttcagact tactggcagc acgcatatta accgtcaaca ccggcgagaa
    57301 gccgctgaca tcctgacgta cgacctgaaa agtgtcgata atgatggcat ccggattagt
    57361 gactttatcc cagcccttac cttcacagga tgtcgcaccg cgtagcgttt ccagcacatg
    57421 ctccttcaga cgaaatccaa tctggtcgga ctcttttacc ggttcgcgat cccagatacc
    57481 gttactgttc gcatcccact gcacaatgac acagtcaccc tgtccgacaa tttccagccc
    57541 ttcgccggta cagatgccat gacaataacc cgccctctgg agatgcttcg cgacggtaaa
    57601 tacccgcagc cagatttcat cttccagcgc cagcttacgg gtgctcgtta aactttcacg
    57661 ctgtaacgca ggcagaaagc gtgccgcccc cagcaacaat acgctactga tcgccatagc
    57721 aatcaacact tccagcagag aaaaaccttg ctcttttaca ggcatccttc tgtttctcct
    57781 tgctgacaaa gccggagtct tccccacggc gaaaccacca gccaccactc gcccgttgag
    57841 tttttgaagc gaatatgccc ggcccatgcg gtattgcgca ggccaaagaa agcaagcgaa
    57901 ggtgtcaggt cgctcatttc gacttcgggc cagcgtggca caaagaccaa tggtgaactg
    57961 ccatgacagg tattggcccc agcagcggaa ctcacaaggc accataacgt cccctccctg
    58021 ataacgctga tactgtggtc gcggttatgc cagttggcat cttcacgtaa atagagcaaa
    58081 tagtcccgcg cctggctggc ggtttgccat agccgttgcg actgctgcca gtattgccag
    58141 ccatagagtc cacttgcgct tagcatgacc aaaatcagca tcgcgaccag cgtttcaatc
    58201 agcgtataac cacgttgtgt tttcatgccg gcagtatgga gcgaggagaa aaaaagacga
    58261 gggccagttt ctatttcttc ggcgcatctt ccggactatt tacgccgttg caggacgttg
    58321 caaaatttcg ggaaggcgtc tcgaagaatt taacggaggg taaaaaaacc gacgcacact
    58381 ggcgtcggct ctggcaggat gtttcgtaat tagatagcca ccggcgcttt aatgcccgga
    58441 tgcggatcgt agccttcaat ctcaaagtct tcgaaacggt agtcgaagat ggattcgggt
    58501 ttacgtttga taatcaactt cggcagcgga cgcggttcgc ggcttaattg cagatgagtt
    58561 tgatccatat ggttgctgta cagatgcgtg tcgccaccgg tccagacaaa atcacccact
    58621 tccagatcgc actgctgcgc catcatatgc accaataacg cgtagctggc aatgttgaac
    58681 ggcaggccga ggaagacgtc acaggagcgc tgataaagct ggcaagagag tttgccgtct
    58741 gccacataga actggaagaa tgcatggcac ggtgccagcg ccattttatc cagttcgcct
    58801 acgttccacg ctgaaacaat aatgcggcgc gaatccgggt cgtttttcag ctggttcagt
    58861 accgtagtga tctggtcaat atgacgacca tctggcgttg gccaggcgcg ccactgttta
    58921 ccatacactg gcccgaggtc gccgttttca tcggcccatt cgtcccagat ggtgacattg
    58981 ttttcgtgta gataagcaat gttagtgtcg ccctgcagaa accacagcag ttcatggatg
    59041 atggaacgca ggtggcaacg tttagttgtc accagcggga atccatcttg caggttaaaa
    59101 cgcatctgat gaccaaaaat ggaaagcgtt ccggttccgg tacggtcgtt tttctgtgtg
    59161 ccttcgtcga gcactttttg catcagttct aaatactgtt tcatggttcc tcaggaaacg
    59221 tgttgctgtg ggctgcgacg atatgcccag accatcatga tcacacccgc gacaatcatc
    59281 gggatggaaa gaatttgccc catgctgatg tactgcaccc aggcaccggt aaactgcgcg
    59341 tcgggctggc ggaaaaactc aacaatgatg cgaaacgcgc cgtaaccaat caggaacaaa
    59401 cctgagacag ctcccattgg gcgtggttta cgaatataca ggttgaggat aataaacagc
    59461 accacacctt ccagcagcag ctcgtaaagc tgtgatgggt ggcgcggcag cacaccgtaa
    59521 gtgtcgaaaa tggattgcca ctgcgggttg gtttgcagca gcaaaatatc ttctgtacgg
    59581 gagccaggga acagcatggc aaacgggaag ttcgggtcaa cgcggcccca caattcaccg
    59641 ttaataaagt tgcccagacg cccggcacca agaccaaacg gaatgagtgg tgcgataaaa
    59701 tcagagacct ggaagaagga acgtttagta cggcgggcga agataatcat caccacgata
    59761 acgccaatca ggccgccgtg gaaagacatg ccgccgtccc agacacggaa cagatacagc
    59821 ggatcggcca taaactgcgg gaaattgtag aacagaacat aaccaatacg tcccccgagg
    59881 aagacgccga ggaagcccgc atagagtaag ttttcaactt catttttggt ccagccgctg
    59941 cccggacgat tcgcccgtcg tgttgccagc cacattgcaa aaatgaaacc caccagatac
    60001 atcaggccgt accagtgaag cgccacgggt cctattgaga aaatgaccgg atcaaactcc
    60061 ggaaaatgca gatagctact ggtcatctgt caccacaagt tcttgttatt tcgctgaaag
    60121 agaacagcga ttgaaatgcg cgccgcaggt ttcaggcgct ccaaaggtgc gaataatagc
    60181 acaaggggac ctggctggtt gccggatacc gttaaaagat atgtatatga tccgcgctat
    60241 aaccctccgc gaatcagccc gcccatgccg cgacgctcca taaaggctgc aacctgatgg
    60301 cgaacttcgg tcgccagttg cgcttccaga ctacgctgcg caagattttc tgcttcggca
    60361 taatcaatgc gccgcagcag gtattttgcc cgcgctacag aacgtccgtt catagacaga
    60421 tggcgatacc caagcccaat gaggattgcc acgcacatgg gatcgcccgc catttcaccg
    60481 cacaaacgga gatcgattcc atgtatttcc gcttcccggg cgatcatcgc cagagctcgt
    60541 aacattgcag gatgaagact gtcataaatg ttcgccaccc gggtattgtt gcgatcaacg
    60601 gccagaatgt attgagtcag atcgttggtg ccaacagaga tgaaatcgac ccgctttgcc
    60661 agatgcggca gcataaatac cattgacggc acttccagca tgatgccgat acgtggtttg
    60721 ggaatttcgt aaccgatcat ctcctcgact tcacgtccgg cacgttcaat caggcggcgt
    60781 gcttcatcaa cttcatcgag gcttgtgacc atcggcaaca gaatattcag gttgcccgta
    60841 gcggcattag cacgcagcat cgcccgcacc tggatcaaga agatctccgg ctgatcgagc
    60901 gtaatgcgaa tcccacgcca acccaggcat ggattctctt cgctgatcgg catgtaaggc
    60961 agctgcttat ctgctccgac atccagcgta cgcaaggtga cgggtttatc attgaacatt
    61021 tgcagcatcc cctgatactg cgccacctgt tcttcttccg acgggaaacc actttgcagc
    61081 atgaatggga tttcagtgcg ataaagaccg atgccatcaa tacggctgcc cagtttttct
    61141 tcatgttccg ggcttaaacc agcattgagc atgactttta tacgctcacc gctttttaac
    61201 tgcgcgggta aattgacgtc atcttccgcc agacggctaa gctcaatctc ttcactaatt
    61261 agccgctgat attcttgcag cagtaccggc tccggatcga ccagcaattc accgcgatag
    61321 ccatcaacga tcagcgtcct acgatgcagc accgaaggct gaatatccgc gcccatcacg
    61381 gtagggatcc ccagcgcacg taccatgatc gcagcatggg agttggctgc gccatctcgc
    61441 acgacaacac cgactaagcg atcctggggc agctcagcaa gcgttgtcgc tgacagttca
    61501 tctgccacca gaatgaaacg ttccggccag gcgttcggcc cttgattagc gtcatcaaga
    61561 tgaaacagca atcgctgacc cagcgcacgt aaatcgccag cccgctcttt gagatagtta
    61621 tcacttagcg cggcaaactg ttcggcaaat ttttcaatga ccgtttttac cgcccactct
    61681 gccaccgagc ctttatcaac ctcggcaaac aattcgcgac gcagccgggt gtccgaaagc
    61741 aggtgcgagt aaagatcgaa aatagccgcc gtttcttttt gtgcaccggc ggcaaagcgt
    61801 ttgctgtagc ggcgaaactc gtttgccgct tcttccagcg ccccggtcag tcgttcgcgt
    61861 tccagagccg gatccagcgt tgatgcctga tacacctgtt ccattaaagg taacgtggca
    61921 tcctgccagc cttcggcaat cgccacacca ggtgctgccg gtaatgcgcg gattcgcgtc
    61981 tggcgatatt gcccaaacaa ggcagtcaac tgcgactgag aaagaatagc tgccatctgg
    62041 gtggcaagcg tcaccaggaa ggattcttca ctttcgtcat actggcgcaa ctctcgttgc
    62101 tgtaccacca gtacaccaag caactggcga cgttgaataa ttggtacgcc taaaaacgcg
    62161 cggaaacgtt cttcttttac ggaggggatg tatttgaagc tggggtgctt ttgcgcatct
    62221 gcaaggttta tcggttccgc cagcctgcca accaggccga cgatcccttc atcaaacgcg
    62281 agcgttacag tgcgaccgcg tggttttttc agcccccggg tcgccatcag gtagtaacaa
    62341 cgtcgatcat gatcggccag gtagaccgaa cagacctcgg tatccatcgc aagacagatg
    62401 tcggtaacca gaatatttaa cgcctcattc aggcgtggtg cgctggctac cttttcgact
    62461 atttcgcgca ggcgagtgag cataattggc gtgacttaac ctcttttacg tcgataagca
    62521 gatgcgtttt gtggttttgg cgtattttcc tgcagtgaca tcaccacact cgcgaactct
    62581 ttcattaccc tacggtagac atcacgttta aatgacacca cctgtctgac cggataccag
    62641 taacttaccc atcgccagcc gtcaaactct ggtgtactgc tggtttgcat attgatttct
    62701 gcatcgccgc tcaccagctg caagagaaac catttttgtt tttggccgat acaaaccggc
    62761 ttcgtgtccc aacgcaccaa acgtttcggt aatttgtagc gcaaccagtt acgcgttgaa
    62821 gcaaggattc gaacgtcttt gcggcttaat cctacttctt caaacaattc acggtacatc
    62881 gcctgctctg cggattctcc ggggttgatt ccgccttgcg gaaattgcca ggagtgctga
    62941 ccaaatcgcc gggcccacat tacctgcccc tggcgattac aaatcacgat acctacgttt
    63001 gggcggtagc catcgtcatc aatcaccgga ctacctcaaa ataaagcttt atatacgaat
    63061 gattgtttca tactccagga agacggtaaa ccactctctg cagggcatta cacactaata
    63121 acaattgaat aactcacagt tatgtgcaga gttataaaca gaggaagggg tggatagccg
    63181 tttttattca ccttttctgt ggatagagtt gtgaagaact acggaattac tacgggaaaa
    63241 cccggagcat tctgaataag cccgatatag acattttaaa atattcatta tcagtcaatg
    63301 cattacatgt aattttagta atgaaaaaga gtaattcgtg acccaggtca cacctctcat
    63361 ttacgggttg gcgaaagatc aaccaatgcc gtatttatcc acagaatgtg ccactaagtt
    63421 aagcactgaa ccactaaaaa ctggagtttc gtcgcacgtc aaggctgtaa atggaaacag
    63481 tagtggaggt ttttcacagt tatcccagct ttctgtggat aacatggtgt aagatcctgt
    63541 ttattttcag tgaccagatt tggaaaaccc gttgcagtgt tgcgcaactc gattaccggc
    63601 aacctaaaaa gcaatataaa tcagagaatt gaacaacgca tgtggaaaaa gttacactgc
    63661 gaatattcgg cacataattg ctgtttgttt tttaatcaag gtatcatgac atgtcccaac
    63721 ctcgcccact gctctctcct cccgaaactg aagaacagtt gttagcgcaa gcacagcaac
    63781 tttctggtta tacattggga gaactggcgg cacttgtcgg gctggttacg ccagagaatt
    63841 taaaacgcga taaaggctgg attggcgtgt tactggagat ctggctaggt gccagcgcag
    63901 ggagtaaacc tgagcaagat tttgctgctc tgggcgtgga acttaaaact atccctgtgg
    63961 atagtcttgg tcgtccgctg gaaacaacat tcgtttgtgt tgccccgtta acgggcaata
    64021 gcggggtgac ctgggaaacc agccacgtgc gccacaaact caaacgcgta ctgtggatac
    64081 cggttgaagg cgagcgcagc atcccgctgg cgcagcgtcg cgttggatca ccgttgctgt
    64141 ggagcccgaa tgaagaggaa gaccggcagc tacgcgaaga ctgggaagaa ttaatggata
    64201 tgattgttct cggtcaggtt gagcggatta ccgctcgtca cggggagtat ttacagatac
    64261 gaccgaaagc agcgaatgcg aaagcgctta ccgaagccat tggtgcccgg ggcgaacgga
    64321 ttctgacgct gccacgcggc ttttatttga agaagaattt caccagtgca ctactggccc
    64381 gtcattttct gatccagtag ccatcgcttt gacctgccgc tttccgggca tataattacc
    64441 gcttcatttt tttggcaggg ctttttagat gttatttgca tggataaccg atcctaacgc
    64501 ctggcttgcg ctcggtacgc tgacgctgct ggagatcgtt cttgggatcg acaatattat
    64561 tttcctttct ctggtggtgg caaagcttcc cacagcacaa cgtgctcatg cgcgccgtct
    64621 ggggttggcg ggagccatgg ttatgcgtct ggcgctgctg gcatcaatcg cctgggttac
    64681 gcgcctgaca aatccgcttt ttacaatatt cagtcaggaa atttctgccc gtgatttgat
    64741 tctgcttctg ggtggcttgt tccttatctg gaaagccagc aaggaaatcc acgaatccat
    64801 tgaaggtgaa gaagaagggc tgaaaacacg cgtttcatca ttcctcggcg ctatcgtgca
    64861 gattatgctg ctggatatta tctttagcct cgactcggtg attacggctg tgggtctgtc
    64921 agatcacctg tttattatga tggcagccgt ggtgattgcc gtaggcgtga tgatgttcgc
    64981 cgcgcgctcg attggtgatt ttgtcgaacg ccatccttcg gtaaaaatgc tggcgctctc
    65041 tttcctgatt ctggtgggct ttaccctgat tctggaaagt ttcgacatcc acgtaccgaa
    65101 aggttacatc tacttcgcga tgttcttctc tattgcggtt gaaagcctca acttgattcg
    65161 caacaaaaag aatccgctct gatactccgt acgctctcct gcgggagggc gtactcactc
    65221 cttttaccct cacagtttaa gattttcctg ctttcaagat atataacgtc ggtttataaa
    65281 cagactatta tcataggtag gccaaatgag gataaccgga tgaaaaaatg ggcagtaata
    65341 atttctgcag tcggactggc gtttgctgtt tccgggtgtt ccagtgatta cgtcatggcg
    65401 accaaagatg gccgtatgat tttgaccgat ggaaaacctg aaattgatga tgataccggg
    65461 ctggtgagtt atcacgatca gcaaggtaac gcgatgcaaa ttaaccgtga tgatgtttcg
    65521 caaattattg aacgttaaca aataaggtca gcatccggct ggccttaaga tttttctctt
    65581 tcccttttcc cttccctctg ccatttttat attccttatg tcgtgattat aaaaaggaaa
    65641 cggctatgca atatcaccgt ataccccaca gttcgctgga agtcagcacg ctggggcttg
    65701 gcacgatgac gtttggtgaa cagaacagcg aagccgacgc ccacgcacaa ctcgactatg
    65761 ccgtcgctca gggcattaac cttatcgacg ttgccgaaat gtacccagta cctccgcgcc
    65821 ccgaaacgca agggttaacc gaaacctacg tcggcaactg gctggcgaaa catggcagcc
    65881 gcgaaaagtt aattatcgcc tccaaagtga gcggaccgtc gcgcaataat gacaagggca
    65941 tccgcccgga tcaggcgctg gatcggaaga atatccgcga agcgctgcat gacagcctca
    66001 agcgcctaca gactgattac ctcgatcttt atcaggtgca ctggccgcag cgcccgacca
    66061 actgcttcgg caaactcggt tatagctgga cggattctgc gcctgcggtt tcgctgctgg
    66121 atacgctgga cgcactggca gagtaccaac gcgcgggaaa aattcgttat atcggcgtgt
    66181 cgaacgaaac tgcatttggc gtaatgcgct acctgcatct ggcggacaaa cacgatctgc
    66241 cgcgtattgt caccattcag aacccttaca gtctgttaaa ccgcagtttt gaagtaggtc
    66301 tggcagaagt cagccagtat gaaggggtcg aactgctggc ctattcgtgc ctgggtttcg
    66361 gcacgctgac cgggaaatat ctcaatggtg caaaacccgc tggcgcacgt aatacgctct
    66421 ttagtcggtt cacccgctat agcggtgagc aaacgcaaaa agccgtcgcg gcgtatgttg
    66481 atatcgccag acgtcatggc ctggaccctg ctcagatggc gctcgcgttt gtacgccgtc
    66541 aaccgtttgt tgccagcact ctgctgggcg caaccacgat ggatcagctg aaaactaaca
    66601 tcgaaagttt gcatctggag ttaagcgaag acgtattagc tgaaattgaa gcggtgcatc
    66661 aggtttatac ttatccggca ccataagatt aacgccggtt aaaaccggcg ttaaatatta
    66721 atgacggcgc tgccagatcc acagcgccgt tattgccagc gcaaacagcg caccgaagcc
    66781 aatgccaatg ggcacgaccg ggatgcctat cattaccgcc agcgagtaaa tgcccagcat
    66841 caacaacatg gcgctgtttt cgccaaggtt ttgtactgca atcgcattcc ccgccccgac
    66901 gcttttttta ccccgctcct gtagcaacgc attgagcgga acgacaaaaa agccccccat
    66961 cacgccaatc agcatcaaca aggcataggc tggcagcagc tcgtgttgca gggaaaaaat
    67021 cagtaccacc acgccaatca aaatcccggc tggcatacag cgtgacacgg tttccagcgt
    67081 aactaacttc gctgccgcac ctgcgccaac cacgatacca atcgctacca tcgcgttgag
    67141 ataggtgggc gtagcgttat cggtaatgcc cagcgccacc ggtacccaca gcaccaacag
    67201 gaaacgcagc gtgacacccg ctccccagaa taaactggtg cccaccagcg aaaaacgcgt
    67261 ttcaccattg cgccatagcg aggtgcaggc attcaggaaa ctgcgggtca tgttgatgag
    67321 attccaggac tgccccggac gcgccgccgc cagtttggga atgtagatat tggcaacgac
    67381 cgcaccaccg taggccagtg cgcatgcggc cagggcgacg aggacatgcc agtcagccag
    67441 cacaccaccg gctacggaac cgagcaaaat cgccgctatg gtagaagctt ccattaaacc
    67501 gttagctttc actaacttac tacccgtggt taattcgccg agaataccgt atttcgccgg
    67561 tgaataggct gcagcaccaa cacccaccag cgtatagccg agaaacggat tgataccaaa
    67621 gcagatactg gctgcgccca gcagcttcag gccgttggca aacatcatca cccggccttt
    67681 ggcgaagcta tccgccacct gcccgacaaa cggcgcaaaa agaatgtaag cacctacaaa
    67741 caccatttgc aggatgggct ggctccactc cggatagaac tgcgctttca gtaacgccag
    67801 agtggcaaac agtagggcat tatcgccaaa cgcagagaga aactgcgcca cgataaccgc
    67861 tttcatcccc ttcgaccaca acgaagtgtt agtgtgcact gactcactca tcgtgttgtt
    67921 ccgcttcgtc tacccagctt ttcaacgtga caaagtcagg tttgccgctg ccaagtaatg
    67981 gcatctgttt cagatagcga atatcgcgcg gtacagcaag ctccggcacg ccgtgctcgc
    68041 gggcatactg ttgcaactta tcgcgcgtca gttcgttatc tgtggtgaaa agcaccagtg
    68101 cctcgccttt gctggcatcg ctcttaatcg cagtggcatg gactttatct ggcgaaacac
    68161 caagtgccag ttgttccacc atttccagcg acaccatttc gcctgcaatt ttggcaaagc
    68221 gttttgcgcg gccctgaatc tgcacaaagc cctgctcgtc aaaacgcaca atatcgccag
    68281 tgtcatacca gccgcgctcc atttcgccgc gaacattctc ggcggtgggc acttccagta
    68341 cacctggctt ctccacccgc agatagccgt tcattatgtt cggccctttc agttgcaggc
    68401 gtccgccctc ttcgatacca gggaccgaca acaggcgcgc atccattcct ggtagaatac
    68461 gccctaccgt accgggtttc gccgccatcg gtacgttgat agaaacgaca ggcgcgcatt
    68521 cggtcacgcc gtagccttca aggatgcgca ggccaaattt atcctgccaa agctgtttgg
    68581 tactttcttg taatttttct gcgcctgcca ccacatagcg tagacgatag aagtcatacg
    68641 ggttggcgaa acgcgcgtag tgaccgagga aagtcgaggt gccgaacaac acggtgcaac
    68701 tgcggtcata caccaactcc ggcacaatgc ggtaatgcag cgggcttgga taaaggaaca
    68761 cttctgcacc tgtaagcagt ggcgtaaaca ggcctaccgt cagcccaaag gagtgaaaca
    68821 gcggtaacgc cgacataaag cgatcgttgg tggtgaagtc ggcaatcgtt ttaatctgct
    68881 cgacattcgc cagaatgctt ttatggctat ggacgacgcc tttcggatgg ccttcagaac
    68941 cggaggtaaa aaggatcagc gcctcttctt ccggctgctg tttaacctgt gccagacgcg
    69001 gcatcagcaa atgagcgaag atccatactt tgtcggcagt ggtgacatct gcttttaaat
    69061 cttccagata gacccagcgc acctgagtaa gttgctccgg cagatgccag agtttgcctt
    69121 tatcgagaaa ctggcgggaa gtgaagatgg ttttgatttc agccgccgta atagcactgg
    69181 tcagcccttt taccccggca gtgtagttca tcattgcggg catgcggcga cgggcgatgg
    69241 ccccaaaaat cactgccgca ctgatgcctg cattgggcag cattaagccg atgcgttcgc
    69301 cttcaacact gtatttttca aggatgcgtc caacaaacag cgttttcgta agcaatttgc
    69361 gataggagtc tggggtaaag ttgacgtctt cgacacattt cttcccggct ccgaagcggt
    69421 acattgcact cagtaaagat tcgtacagcg tttcacgcgg gcgcaccgcc attcgcgctt
    69481 ccatcattat ttgatgcagc atttcgccag cgattttgcg acggtcacgg gcacgcggcg
    69541 catccggcat cgccacctgc gttggtggca aaatatgcag agtaatttgc gggaacaagc
    69601 gacgtttaac cagacctttc aggcggctga agtgcgtaag ttccgcccct tcaatacgca
    69661 caggaataac cgttgcacca gacttcgccg cgacaaaacc cgcgccatcg tagattttca
    69721 tcagcgagcc tgtcgtggtg atgcgtcctt cagggaaaat caccactggt cggccctgtt
    69781 ccaccagacg taccagatgt ttaatagcca taggttgcgt cgggtcgaga ggaacaaagt
    69841 cgataaatga tttcagccaa cgcatatacc actgttggct tattgaggtg taaacggcaa
    69901 acactggacg cacaggtaaa aacagtccaa gcaaaatgcc atcaataaaa gagacgtgat
    69961 taggcgtaat tagaacgcgc tcgcccttca gtgcctgggt gtcacccgta acgcgaacgc
    70021 gatacaaaac acggcacaaa tttcgaaaaa agctaaaaag cattccaact ccctttgctc
    70081 tgattcagta aaagcgaatg gagggagatt acacgagata aagaacgcga gcgacagtaa
    70141 attaggtgcg aaaaaaaacc tgcgcatccg cgcaggttgg tgcaagagac agggtacgaa
    70201 gagcgtaccg aataatctca ccaatcaata cctctgggat cttgattgtg gtctgcacga
    70261 cgactcttcg ccagcgagaa aacgcaaagg aatgaaggga aatgcaacga ggtgtgtaaa
    70321 ttgtcggtta ctgttacaga ttgatgaccg gcaaaaaaaa cctgcgcatc tgcgcaggct
    70381 ggtgtaattc atgtgctcaa cccgaagttg acttcaccta tcaatacctc tgggatcacc
    70441 actttagcaa cctgaagcca aacgccacca gcggtcaatc gcaacagcgt ttcgcaaagt
    70501 gtaaccaaag gtttgcaatc tctttttttg tcttacttat ttgcgtttgg ctcacattcc
    70561 cacgatgaaa acacgccacc ccttgaacca acgggcgttt tccgtaacac tgaaagaatg
    70621 taagcgttta cccactaagg tattttcatg gcgaccataa aggatgtagc ccgactggca
    70681 ggcgtttcag tcgccaccgt ttcccgcgtc attaataatt cacccaaagc cagcgaagct
    70741 tcccggctgg ctgtgcatag tgcaatggag tctcttagct atcacccgaa cgccaacgcc
    70801 cgtgcgctgg cgcagcagac cactgaaacg gtcggtctgg tcgttggtga tgtttccgat
    70861 ccgtttttcg gtgcaatggt gaaagcggtc gaacaggtgg cttatcacac cggtaatttt
    70921 ttattgattg gcaacggtta ccacaacgaa caaaaagagc gtcaggccat tgagcaactg
    70981 atccgccatc gctgtgctgc gttggtcgtc catgccaaaa tgatcccgga tgctgattta
    71041 gcctcattaa tgaaacaaat gcccggtatg gtgctgatca accgtatcct gcctggcttt
    71101 gaaaaccgtt gtattgctct ggacgatcgt tacggtgcct ggctggcaac gcgtcattta
    71161 attcagcaag gtcatacccg cattggttat ctgtgctcta accactctat ttctgacgcc
    71221 gaagatcgtc tgcaagggta ttacgatgcc cttgctgaaa gtggtattgc ggccaatgac
    71281 cggctggtga catttggcga accagacgaa agcggcggcg aacaggcaat gaccgagctt
    71341 ttgggacgag gaagaaattt cactgcggta gcctgttata acgattcaat ggcggcgggt
    71401 gcgatgggcg ttctcaatga taatggtatt gatgtaccgg gtgagatttc gttaattggc
    71461 tttgatgatg tgctggtgtc acgctatgtg cgtccgcgcc tgaccaccgt gcgttaccca
    71521 atcgtgacga tggcgaccca ggctgccgaa ctggctttgg cgctggcgga taatcgccct
    71581 ctcccggaaa tcactaatgt ctttagtccg acgctggtac gtcgtcattc agtgtcaact
    71641 ccgtcgctgg aggcaagtca tcatgcaacc agcgactaac cgcagttaaa gcaattccag
    71701 cgccagtaat tcttcgatgg tctggcgacg gcgaatcaac cgcgcctgac cattatcaaa
    71761 cagaacttct ggtaacagcg gacggctatt gtagttggat gacattgatg cgccatatgc
    71821 ccctgtatca tgcagtacca gataatcacc tgccttcact tccggcaagg cgcgggtttc
    71881 aacatttccc ccttcctgct gggtaaagac atcgcccgat tcacataacg gtccggcgac
    71941 gacggtttcc accgttggcg cgtgttccag agaacgacca tcagctgcca gggcactgat
    72001 atggtggtaa ctaccgtaca ttgccgggcg catcagatcg ttgaacccgg catcaaccag
    72061 cacaaagtgg cggctcccca tttgtttgac gctccgcacc tgagtaatta atacgccaga
    72121 ctgcgctacc aggaagcgac ccggttcaat ttccagtttc acagggtggc ccaaatggcg
    72181 ggcgatttgc tcacgcgcgg cattccacag accataataa tgttcggtat caaccgcctc
    72241 ttcaccctgt tgataaggaa cagaaagccc accgcccgca gaaatagcct gtaaatcctg
    72301 accgaattcg atgacctgac gcaccatagc accacacacc tgttccagat gggcataatc
    72361 aacgccagaa ccaatgtgca tgtgaatgcc gaccagctgc agatgatgac gttgtatcac
    72421 gtccagtgcg gcgggcagat cggtgtacca gataccgtgc ttgctgtttt cgccaccggt
    72481 attggttttt tggctatgtc cgtgaccaaa ccccggatta acgcgcagcc atacccgatg
    72541 ccctggcgaa acctggccca gttggtcgag catatcaaca gaacccgcat tcaccggaat
    72601 ttgcaattca ctgacgcgtt caagcgtcgc ctgatcgata acatctgccg taaaaacaat
    72661 atcatcgggg tgcgtttgcg gattgtaacc cgccgccaac gcacgctcta tttcgcctaa
    72721 cgagacggaa tccactttca cgccctgctc acgcattaag cgcaaaatat gaatattgga
    72781 acaggctttc tgtgcaaagc gcaccacatc aaactgtttc agcgctgcaa tctgccgacg
    72841 aataatttgc gcatcgtaga cccacaccgg gcagccaaat tcagcgggca aacgcagcag
    72901 attttcggcg gtgagatcgg tatcggtgct gaacagtgaa tgtggcataa caaactccag
    72961 ataagtgctt ttttatgatt acgccacatc ataaaaagaa taaaaaatat cgatttatgt
    73021 cgagtctatg caaaaatgat atggattacc ggattgcgag agagcgctaa tggccgccgt
    73081 taacttacgt catattgaaa tttttcatgc ggtaatgacc gccggaagcc tgactgaggc
    73141 ggcacacctg ctacacacct cacagccaac cgtcagccgc gaacttgcgc gctttgagaa
    73201 ggtgatcggg ctgaaattgt ttgagcgcgt acgtgggcga ttacatccta ccgtgcaagg
    73261 actgcgtctg tttgaagaag tgcaacgatc ctggtacgga ctggatcgca ttgtcagcgc
    73321 cgcagaaagt ctgcgcgagt ttcgccaggg agaactgtct attgcctgcc tgccggtctt
    73381 ttcgcaatct tttttaccgc agctcctgca accctttctg gcacgttatc ccgatgtcag
    73441 cttaaatatc gtgccccagg aatcaccgct acttgaagag tggctctcgg cccagcgtca
    73501 tgatttagga ctcactgaaa cgctccatac gcctgcggga acagaacgta ccgaattact
    73561 ctctttagat gaagtgtgtg tgttacctcc gggtcatccg ctggcggtaa aaaaggtatt
    73621 aacgccggat gattttcagg gtgagaacta catcagcctt tcccgtactg acagctatcg
    73681 ccagttgctg gatcagctat ttactgaaca tcaggttaaa cgacgcatga tcgtagaaac
    73741 ccacagcgcc gcgtcagtct gcgcaatggt acgggcgggg gtaggtgttt cggtggttaa
    73801 cccgctcacc gcactagatt atgcggcaag cggtttagtg gtgcggcggt tcagtattgc
    73861 ggttccgttc accgtcagcc tgatccgccc cctgcaccgc ccgtcatcag cgctggttca
    73921 ggcgtttagt gggcatttac aagcggggtt accgaaactg gtcacttctc ttgacgctat
    73981 tttgtcgtca gctacgacag cataaaagcg acagcatcct cggcatggat cgccgcggta
    74041 tcaaacacag gcaaaacact gcgctcttct ggcaccagta aaccaatttc tgtgcagcca
    74101 aaaatgacgc cctgtgcgcc ctgttctgca aggcgagcaa tcacttgcgc ataataagcg
    74161 cgtgacgctt cggtaaattg ccccagacac agttcttcaa aaataatctg attaattttc
    74221 gcccgttcat ccgcttcagg aataagacaa ttgatggaaa attgttccgt cagccgcccg
    74281 cgataaaaat cctgttccat ggtgtaacgc gtacccagca gcgccacacg agtcattccg
    74341 gccccggtaa ttgcacgtcc ggtggcatcc gcaatgtgta agaaaggcag agtgcaacgt
    74401 gactcaatgg catccgccac tttatgcatc gtattggtac ataacacaat accttctgcg
    74461 cccgcccgct gtaagccaag cgccgcctca gccagaatgt ccccggtttt atcccattcc
    74521 ccgcgacgct ggcactcttc tatttcatga aaatcgacgc tatgtagcag cacttgcgca
    74581 gagtgaagcc caccaagccg ctgtttaatg ccttcattta tcaaacgata gtaaggaatg
    74641 gtggattccc agctcattcc tcccagcaaa ccaattgttt tcattcctct ctcctgatgt
    74701 gtgttaccgc aacaaggctg aataaggaac gagacaaacg cctcaacggc caagtgccca
    74761 atctctatta acgaaaaaag ggccggatgt acagcacatc cggcccgtga aatcagacgc
    74821 cgatatttct caacttctcg cctgccatca gtttgcgttc gatatgttcc agcgtgacat
    74881 ttttggtttc cggaatgagc cagaaagtaa tgcccacaaa cgcaatgttc agcgcagtgt
    74941 agagccagaa cgtaccggca gcgccaatgc tatcaagcag tgtcaggaag gtcgcgccga
    75001 taatcatatt cgacacccag ttcgtggtgg tcgaacaggt aataccgaaa tcgcggcatt
    75061 tcagcggctg aatttcagag cacaggatcc acaccactgg cgcggcgctc atcgcataac
    75121 cggcaataca catcatcgtc atgccaacag agagccagga caagccactg gaagccgtac
    75181 cgttatcaaa ctgcatcagg caatagccca gcaccagagt gcctaacgcc atcacgctga
    75241 aaccaatttt cagagccggt ttacgccctg ctttatctac cgtaaacacc gcaataaagg
    75301 tggcgaacat aaaggtcagc cctacgacca gagtcgcaat catctgttgt tctgtggtcg
    75361 taaagcccgc cattttgaag atacgcggcg cgtagtacat gatgatgttc ataccggtaa
    75421 actgctgcat cgcctgcaac aacataccga gaaacacagc acgacggacg ttacggttga
    75481 tcttaaacag tgcccaaccg ccctgtttta acttcaggct ttcacgaatt tcgttgagtt
    75541 cttctcgcgc tttttccgac gtatcgcgca gcatacgcaa tacttcttcc gcctcaatat
    75601 gacgcccctt ttccgccagc cagcgcgggc tatttggcag gaagactacc agaataatca
    75661 gcagaactgc tggtaaagca agaaccccca acattgcgcg ccagttaccg ctataactga
    75721 acgctgtatc ggataaaaac gccagcacga tgccgagtgt gaccatcaac tggtacatac
    75781 tgatcatctt accgcgaacg ttttcacttg ccatttcaga aagatacaga ggagcggtgt
    75841 aagacgcgat cccgacagca atgcccagca ccacacgagc ggcgattaac atctctacgc
    75901 tggtcgcaaa agcggaccct atagaaccga gtacaaacag gatggccccc gccatcaggc
    75961 tgtatttacg ccccaggcgg aacgacagcc aaccattaaa cagcgcacca attgctgcac
    76021 cgagcatcat gctactaacc acccattcct gcaaacgact ggtcagcaca aagtgatcgg
    76081 taatgaacgg caacgctccg gcgattacgc cgatatcaag accaaataac aatcctgcga
    76141 ccgcagcagc taccgaaaca aacatattca tacgccgcgt atcccgcaaa gaacgtggcg
    76201 ttaaagcaga ttccgtattg atagtaacca ttttttcctg ccagcagaga gtaagacata
    76261 gtgaaaaaat acgtgaacaa ctcacgcagg tgtcaggtcg gaaacagcat aaatatggat
    76321 taaattgctg cgacatgtcg ttatgtgatg gatattccaa ttttcaaatt aagttgaatt
    76381 attgagatta ttattaacca cctaatttta cagcagataa aattcataaa gttcattaat
    76441 tgataattaa tatggattat ttcataacca tgatatggat tatgatgatc tacaggtata
    76501 aaaaaccctg ccatgcggca gggtcataaa agtaagaaga atgaattaac gcgctagcca
    76561 accgccatcc acggcaatgg tataaccatt cacataatct gaagcgctgg aggcaaggaa
    76621 cactatcggc cccatcaggt cactcggcag tccccaacga ccagctggaa tgcggtcgag
    76681 aatttccgcg ctacgttgtt catctgcccg tagttgttga gtattgttgg tcgccatgta
    76741 acccggggct atcgcattaa cattaatgtt gtgtttagcc cattcgttcg ccatcaatcg
    76801 cgtcacaccc atcacgccgc tttttgatgc ggtataagaa ggcacacgga tcccgccctg
    76861 gaaggagagc attgacgcga tattgataat cttgccgcca ttgccttgcg cgataaagtg
    76921 tttcgccgct gcctgagaca tgaagaatac gctcttgata ttcaggttca tgacatcgtc
    76981 ccagtccttt tcgctgaact cgagagcatc ttcgcggcga atcaatccgg cgttattcac
    77041 caggatatca atatgaccaa actccgctac cgcgcgatcc agcagtgctg gaataccatc
    77101 aatctttcgc agatcggcgg tcaggcttaa aaaacgacgc cccagcgctg tgacctgctc
    77161 gatggtttca gtcggttcaa cgatgttaat gccaacaatg tcacagcccg cttgcgccag
    77221 ccccaacgcc atcccctgac ccagtccagt atcacaacca gtgacgaccg caactttacc
    77281 ttcgagagaa aatgcactta aaatcataac aataccttat tcgtttatgc ccacaactag
    77341 cgcaaatctt taacggccac atggtccata tcatcaaaga cctggttttc accgaccatg
    77401 ccccagataa aggtataagc tttggttccg acaccggaat ggatcgacca gctcggggag
    77461 atcaccgcct gctcgttatg catcacaata tgacgcgttt cttgcggctg ccccatcatg
    77521 tggaaaacgc aggcgtcatc atccatattg aaatagaaat aaacttccat ccggcgctcg
    77581 tgggtgtgac acggcatggt gttccacaag ttacccggag ccagctccgt cagccccata
    77641 ctcaattggc aggtttccag tacatccggg acaaaatatt tgttaatcgt gcgacggtta
    77701 ctggtgaggt tatcgcctaa cgtgactgga gatacttcgt ccggtgtgac ttttttggtg
    77761 ggatacgccg tatgcgcggg tgcgcaattg taataaaact tcgccggagt gccggtatca
    77821 atactggcaa agacaacttc ttttgcacct ttaccaacat acagggcgtc gcggtgaccg
    77881 atttcatagc attggccatc gacagtaatc gtaccggcac cgccaatatt gataacacct
    77941 aactcgcgac gttcaaggaa atagcttacg ccgagttgtt taccaacttc cccgccaacg
    78001 gaaaccgttt tagttatcgg cataatgccg ccaacaataa ttcggtcaat gtggctgtaa
    78061 accatggtgt actcatcggc gacaaatacc ttttcaacca aaaattcatt gcgcagccct
    78121 tgggtatcca gcgtttttgc gtgcgcactg tggatgctct gtcttacgtc cacatcaacc
    78181 tccgataatc agtgaagcgt gaaaatagaa aacgatagtg aaacactgtt tcgttttctc
    78241 tataaaggga tgatatgccc atgggctagg gttttcaatt aaaaataaaa caatgtttca
    78301 tttttaagtt aaggattaaa aaaagtgcag tgtcgatcac gaatatgtca tgagaatgga
    78361 aaaatgaggg agcccagaaa atgtatgtcg acttgccagc catcattatt caacagatta
    78421 atgacggcag atatttatcg gtaaggagga aatgcagagc tattcgtcac gttcaatggt
    78481 caatgccaca ccctggcccc cgccgataca aagcgttgcc agtcctttgc gggcattacg
    78541 tttcaccatt tcatgaacca gagaaaccag gattcggcaa ccggaagcgc ctatcgggtg
    78601 accgagtgcg atcgcgccac cattgacatt gacccgacgc tcatcccact caagcatctt
    78661 gccaaccgaa agcgcctgtg cagcaaacgc ttcattagcc tcgataagat cgacttcagc
    78721 caactgccag cctacacgct ccaggcaacg gcgggtcgca tacaccggcg caattcccat
    78781 caatgccgga tctacaccaa cgctggcaaa tgcgcgaatg cgggccagca cgggtaaatt
    78841 caacgctcgt gctttggctt cgctcatcat cattaccgca gctgcgccat cgtttatgga
    78901 tgatgcatta cccgctgtca cagaaccgag actatcaaat gaaggattta aacgggctaa
    78961 gccttctgcg ctggcgtcag tgcgtggctg ttcatcggta tcaacaacca acgtctgccc
    79021 gttactttgg gtcattaccg ggacgatctc atctttaaat cgtccggcgt caatcgccgc
    79081 tcgcgctttt tgttgcgagc taagtgcgta agcatcctgc aactgacggc tgatgccata
    79141 ttcgcgagcc agattttcgg cggtgacacc aatatgataa tcattgaagg catcccacaa
    79201 cccatcatgc acaagactgt caaccaactg gctattgcca agctgtgcac cggtgcggct
    79261 atcagtcaga acatgtggtg cgcggctcat gttttcctgg ccaccggcga tgacaatatc
    79321 agcctcgcca cactgtatcg cctgagtagc cagatgcagt gctttaagcc cggaaccgca
    79381 aacgtcatta atagtgattg cagaaacgct attaggcaga ccacctttaa tagccgattg
    79441 ccttgccgga ttctgccctg cccctgcagt caacacctga ccaagaatta cttcatccac
    79501 cgcatatgca ggaacgccgg tacgttctat taacgctttc acgaccagac taccaagttc
    79561 cacggcggaa tgacccgcta acgcaccacg aaagcagccg ataggtgtcc gtaacgcccc
    79621 gacaatcaca acgtctttca tcacaacctc gcaccaatta acagtgcaat agtaaatgat
    79681 tgttaattac agttatctta attgtttaaa aaaagtgatt tttatcacaa aggaaatatg
    79741 cctgagcagc agtcagagac ataactggca cgtaaggttt gcaaccacta acccaccaat
    79801 agaggggtag atagggcgtt aatctcccat acttaacctg gtttatggta aattgccctc
    79861 cattttgttt aatttgtaga tgatacgttc agataatgtc taatatttgg tctaaagaag
    79921 aaactctgtg gagtttcgcg ctctacggca cagccgttgg tgcaggcacg ctcttccttc
    79981 ctattcagtt aggttcggca ggggctgtgg tcctgtttat tactgctctg gtcgcctggc
    80041 ctttaacata ttggccacat aaagccttgt gccagttcat cctctcatca aaaacatcag
    80101 caggtgaagg gataacgggc gcggtaacac actactatgg caagaagatt ggtaatctga
    80161 ttaccacgct gtacttcatc gccttttttg tcgtcgtgtt gatatatgca gtggcaatta
    80221 ccaactcact tacggaacag ctggcaaagc atatggttat tgatcttcgc atccgtatgt
    80281 tggtgagtct gggtgttgta ttaattctga atctcatttt tctgatggga cgtcatgcca
    80341 ctattcgggt aatgggattt ttggtattcc cattgattgc ctatttctta tttctttcca
    80401 tttaccttgt cggtagttgg caacctgatc tattaacaac ccaggtagag ttcaatcaga
    80461 atacccttca ccagatatgg atatcgattc ccgtgatggt tttcgccttt agccatacgc
    80521 ccattatttc tacgtttgcc atagacagac gtgaaaaata tggcgaacac gctatggata
    80581 aatgcaaaaa aattatgaaa gtcgcttatc tcatcatctg cataagtgta ctgttctttg
    80641 tctttagctg cctgctttct attccacctt cgtatattga agctgctaaa gaagaagggg
    80701 tcaccatttt atcggcgctt tctatgctgc cgaacgcccc agcatggttg tcaatttccg
    80761 ggattattgt cgcagtagtt gcgatgtcga aatcattcct gggtacgtac tttggcgtta
    80821 ttgaaggtgc cacagaggtc gtcaaaacaa cactacagca ggttggtgta aagaaaagtc
    80881 gtgcatttaa ccgcgcacta tcaattatgt tggtatcgct gattaccttc attgtttgtt
    80941 gcattaaccc gaacgcgatt tcgatgattt acgcgatcag cggcccgctc attgccatga
    81001 tacttttcat catgcctacg ctgtcaacgt atctcatccc ggcgcttaaa ccctggcgtt
    81061 ccatcggaaa tctgattacg ctgatcgtgg gtatcctgtg cgtatcggta atgttcttta
    81121 gctaatatca gttgtggatg gttcaaaatt gctacaattt tgaaccattc catttttcat
    81181 aatattcatt tgttattatt ccaccctatc acttctctcg tcatatccta gtattatcag
    81241 ttagttaaac acacaaagag atctgaacat cttaaataag actatttaag atgcataact
    81301 tagattcgca agatatcttc tggtcattca aaaacaattt gcgatataga tattcttata
    81361 ccatgagata gttatctgga ccgctctcaa ccatgcaaga ttaaatcagt gaaacataat
    81421 catatttgat aacgagaaat gcatttttaa atgccttact cagaattata gcaaatacag
    81481 attaatcgca atttttcccg gcaaaattac aaaatcatgg tgtattgaca tcatcaataa
    81541 ccaatgaaat tatgcaatta tatacggata gggaggttct taacatgggg ctttgtagtc
    81601 gttataaaag tcttacatgc aatagttgct caatgcattg ccaaataatg ccagaagagt
    81661 caccgcgttt gcagtattgc gcaaactcgt gtttttgtat gtggcccgaa gaaagttcat
    81721 attttaatcg tggtgtggta gaaggtatct taacaaaaaa ccacaatgcg agattaagcg
    81781 gatatatttt tgtcgatttt tcagtaagtt ttttacgtct attccttgaa aaagactgga
    81841 ttgactatct tgcaagtact gacatgggga ttgttttagt cagcgaccgc aatatgcaat
    81901 cgttagctaa ttactggcga aaacacaact cagcaatatc tgctgtcata tataatgatg
    81961 atggtcttga tgttgccaat gaaaagatca gacaactatt tattggtcgt tatttatcat
    82021 ttaccagagg taacacatta actcagatgg aattcaccat aatggggtat atggtttctg
    82081 gttataatcc atatcagatt gctgaagttc tggatatgga tatccgtagc atctacgcgt
    82141 acaagcaacg aatcgaaaag agaatgggtg gtaaaataaa cgaattattt attcgttcac
    82201 attcggtcca acattgatac tcaacgacca gccagaatca tactctgttt atacgggcat
    82261 ttattgaaat gtccgtattt tataaatagg ccgtcccctc aagagtaaac accatagtat
    82321 ttaaaaccat cacacgaaaa attcagaagc attacgaaat atgaatttac aaacaatagt
    82381 ggcataaatg ttaaccatgt taatttacgt aaagtt
//
LOCUS       DAPHKZ010000003        82232 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.003, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000003 DAPHKZ010000000
VERSION     DAPHKZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 82232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82232
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.003"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..159
                     /locus_tag="RH288_000160"
     CDS             <1..159
                     /locus_tag="RH288_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HDV4029266.1"
                     /translation="FIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISISKII
                     GGCGPTAQ"
     gene            403..1791
                     /gene="frlA"
                     /locus_tag="RH288_000161"
     CDS             403..1791
                     /gene="frlA"
                     /locus_tag="RH288_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417829.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine/psicoselysine transporter"
                     /protein_id="HDV4029267.1"
                     /translation="MTANSPLQRIGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSG
                     IFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGS
                     RPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHL
                     RSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGI
                     SATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKL
                     ANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFF
                     KCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWC
                     RKRDDYKPLWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAF
                     WAKRSRQLNALS"
     gene            1812..2834
                     /gene="frlB"
                     /locus_tag="RH288_000162"
     CDS             1812..2834
                     /gene="frlB"
                     /locus_tag="RH288_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417830.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-phosphate deglycase"
                     /protein_id="HDV4029268.1"
                     /translation="MLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDI
                     DRIYFVACGSPLNAAQTAKHLADRFSDLQVYAISGWEFCDNTPYRLDDRCAVIGVSDY
                     GKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVV
                     LEMITRLAPNAEIGKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGP
                     LRPLGYKEGIVTLMEFTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTER
                     AINFVKQRTDNVIVIDYAEISQGLHPWLAPFLMFVPMEWLCYYLSIYKDHNPDERRYY
                     GGLVEY"
     gene            2884..3714
                     /gene="frlC"
                     /locus_tag="RH288_000163"
     CDS             2884..3714
                     /gene="frlC"
                     /locus_tag="RH288_000163"
                     /EC_number="5.1.3.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 3-epimerase"
                     /protein_id="HDV4029269.1"
                     /translation="MKTGMFTCGHQRLPIEHAFRDASELGYDGIEIWGGRPHAFAPDL
                     KAGGIKQIKALAQTYQMPIIGYTPETNGYPYNMMLGDEHMRRESLDMIKLAMDMAKEM
                     NAGYTLISAAHAGYLTPPNVIWGRLAENLSELCEYAENIGMDLILEPLTPYESNVVCN
                     ANDVLHALALVPSPRLFSMVDICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGASDTH
                     YIPGEGKMPLRELMRDIIERGYEGYCTVELVTMYMNEPRLYARQALERFRALLPEDER
                     "
     gene            3711..4496
                     /gene="frlD"
                     /locus_tag="RH288_000164"
     CDS             3711..4496
                     /gene="frlD"
                     /locus_tag="RH288_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HDV4029270.1"
                     /translation="MKTLATIGDNCVDIYPQLNKAFSGGNAVNVAVYCTRYGIQPGCI
                     TWVGDDDYGTKLKQDLARMGVDISHVHTKHGVTAQTQVELHDNDRVFGDYTEGVMADF
                     ALSEEDYAWLAQYDIVHAAIWGHAEDAFPQLHAAGKLTAFDFSDKWDSPLWQTLVPHL
                     DFAFASAPQEDETLRLKMKAIVARGAGTVIVTLGENGSIAWDGAQFWRQAPEPVTVID
                     TMGAGDSFIAGFLCGWSAGMTLPQAIAQGTACAAKTIQYHGAW"
     gene            4596..5327
                     /gene="phoB"
                     /locus_tag="RH288_000165"
     CDS             4596..5327
                     /gene="phoB"
                     /locus_tag="RH288_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417834.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PhoB"
                     /protein_id="HDV4029271.1"
                     /translation="MSATDRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQ
                     YNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVENALLTVSGFTDFCVSQGKATK
                     EKVIEQERVSAAPFCEKLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEI
                     YVEGSSTYQLFQERFDTRVVSDKKTIDIFAATRPQAKWLKCELGEPLFRISKIAFDQN
                     DKPVHVSELFCRANRITLTIDNKRH"
     gene            complement(5479..6564)
                     /locus_tag="RH288_000166"
     CDS             complement(5479..6564)
                     /locus_tag="RH288_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDV4029272.1"
                     /translation="MKTFPLQSLTIIEAQQKQFALVDSICRHFPGSEFLTGGDLGLTP
                     GLNQPRVTQRVEQVLADAFHAQAAALVQGAGTGAIRAGLAALLKPGQRLLVHDAPVYP
                     TTRVIIEQMGLTLITVDFNDLSALKQVVDEQQPDAALVQHTRQQPQDSYVLADVLATL
                     RAAGVPALTDDNYAVMKVARIGCECGANVSTFSCFKLFGPEGVGAVVGDADVINRIRA
                     TLYSGGSQIQGAQALEVLRGLVFAPVMHAVQAGVSERLLALLNGGAVPEVKSAVIANA
                     QSKVLIVEFHQPIAARVLEEAQKRGALPYPVGAESKYEIPPLFYRLSGTFRQANPQSE
                     HCAIRINPNRSGEETVLRILRESIASI"
     gene            complement(6576..7880)
                     /locus_tag="RH288_000167"
     CDS             complement(6576..7880)
                     /locus_tag="RH288_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfT family protein"
                     /protein_id="HDV4029273.1"
                     /translation="MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYM
                     NRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGA
                     IWGVLILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLI
                     AAVVVLMTRVVVVRYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGLSVF
                     EERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLIN
                     QAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVGYLSPNPMVAAVLGAVVISA
                     EVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAV
                     AIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA"
     gene            complement(7892..8245)
                     /locus_tag="RH288_000168"
     CDS             complement(7892..8245)
                     /locus_tag="RH288_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2620 domain-containing protein"
                     /protein_id="HDV4029274.1"
                     /translation="MKKIGVAGLQREQIKKTIEATAPGCFEVFIHNDMEAAMKVKSGQ
                     LDYYIGACNTGAGAALSIAIAVIGYNKSCTIAKPGIKAKDEHIAKMIAEGKVAFGLSV
                     EHVEHAIPMLINHLK"
     gene            complement(8256..9134)
                     /locus_tag="RH288_000169"
     CDS             complement(8256..9134)
                     /locus_tag="RH288_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase-related protein"
                     /protein_id="HDV4029275.1"
                     /translation="MSFDPTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLM
                     TRGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVACTGYYQDAFFPEHVATRSVQELA
                     QEMVDEIEQGIDGTELKAGIIAEIGTSEGKITPLEEKVFIAAALAHNQTGRPISTHTS
                     FSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYP
                     DEKRIAMLHALRDRGLLNRVMLSMDITRRSHLKANGGYGYDYLLTTFIPQLRQSGFSQ
                     ADVDVMLRENPSQFFQ"
     gene            complement(9131..10357)
                     /locus_tag="RH288_000170"
     CDS             complement(9131..10357)
                     /locus_tag="RH288_000170"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDV4029276.1"
                     /translation="MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQ
                     LPTLEKLGLINALGYAPGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRM
                     PFRDVIDRVEQALVSAGWQVERRGDDLQFLWVNQAVAIGDNLEADLGQVYNITANLSV
                     ISFDDAIKIGRIVREQVQVGRVITFGGLLTDSQRILDAAESKEGRFIGINAPRSGAYD
                     NGFQVVHMGYGVDEKVQVPQKLYEAGVPTVLVGKVADIVNNPYGVSWQNLVDSQRIMD
                     ITLNEFNTHPTAFICTNIQETDLAGHAEDVARYAERLQVVDRNLARLVEAMQPDDCLV
                     VMADHGNDPTIGHSHHTREVVPVLVYQQGMIATQLGVRTTLSDVGATVCEFFRAPPPQ
                     NGRSFLSSLRFAGDTL"
     gene            complement(10357..11520)
                     /locus_tag="RH288_000171"
     CDS             complement(10357..11520)
                     /locus_tag="RH288_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfX family PLP-dependent enzyme"
                     /protein_id="HDV4029277.1"
                     /translation="MFVEALKRQNPALISAALSLWQQGKIAPDSWVIDVDQILENGKR
                     LIETARLYGIELYLMTKQFGRNPWLAEKLLALGYSGIVAVDYKEARVMRRAGLPVAHQ
                     GHLVQIPCHQVADAVEQGTDVITVFTLDKAREVSAAAVKAGRIQSVLLKVYSDDDFLY
                     PGQESGFALKVLPEIVAEIQNLPGLHLAGLTHFPCLLWDEAVGKVLPTPNLHTLIQAR
                     DQLAKSGIALEQLNAPSATSCTSLPLLAQYGVTHAEPGHALTGTIPANQQGDQPERIA
                     MLWLSEISHHFRGDSYCYGGGYYRRGHAQHALVFTPENQKITETNLKTVDDSSIDYTL
                     PLAGEFPVSSAVVLCFRTQIFVTRSDVVLVSGIHRGEPEIVGRYDSLGNSLGA"
     gene            complement(11604..11966)
                     /locus_tag="RH288_000172"
     CDS             complement(11604..11966)
                     /locus_tag="RH288_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417841.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDV4029278.1"
                     /translation="METRLNLLCEAGVIDKDICKGMMQVVNVLETECHLPVRSEQGTM
                     AMTHMASALMRSRRGEEIEPLDNELLAELAQSSHWQAVVQLHQVLLKEFALEVNPCEE
                     GYLLANLYGLWMAANEEV"
     gene            complement(11983..12888)
                     /locus_tag="RH288_000173"
     CDS             complement(11983..12888)
                     /locus_tag="RH288_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029279.1"
                     /translation="MRRTFIKKEGVVITTLARYLLGEKCGNRLKTIDELANECRSSVG
                     LTQAALKTLESSGAIRIERRGRNGSYLVEMDNKALLTHVDINNVVCAMPLPYTRLYEG
                     LASGLKAQFDGIPFYYAHMRGADIRVECLLNGVYDMAVVSRLAAESYLTQKGLCLALE
                     LGPHTYVGEHQLICRKGESANVKRVGLDNRSADQKIMTDVFFGGSDVERVDLSYHESL
                     QRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATEAVVLTRVDDYPMQQLL
                     RAVVDKHALLAHQQRVVSGEQEPSY"
     gene            complement(13178..14182)
                     /gene="trpS"
                     /locus_tag="RH288_000174"
     CDS             complement(13178..14182)
                     /gene="trpS"
                     /locus_tag="RH288_000174"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDV4029280.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNALYGEIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP
                     "
     gene            complement(14175..14933)
                     /gene="gph"
                     /locus_tag="RH288_000175"
     CDS             complement(14175..14933)
                     /gene="gph"
                     /locus_tag="RH288_000175"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HDV4029281.1"
                     /translation="MNKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADVLMERALTWARQERATQRKTMGKPPVDDDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
                     DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     AIDLSQPDVIYQSINDLLPALGLPHSENQESKND"
     gene            complement(14926..15603)
                     /gene="rpe"
                     /locus_tag="RH288_000176"
     CDS             complement(14926..15603)
                     /gene="rpe"
                     /locus_tag="RH288_000176"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDV4029282.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSE
                     LAKVSHE"
     gene            complement(15621..16457)
                     /gene="dam"
                     /locus_tag="RH288_000177"
     CDS             complement(15621..16457)
                     /gene="dam"
                     /locus_tag="RH288_000177"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HDV4029283.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVE
                     RHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPA
                     KK"
     gene            complement(16564..17850)
                     /gene="damX"
                     /locus_tag="RH288_000178"
     CDS             complement(16564..17850)
                     /gene="damX"
                     /locus_tag="RH288_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HDV4029284.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDI
                     ELDDTDDRRPTRAQKERNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQ
                     YMMMGVGILVLLLLIIGIGSALKAPSTTSSDQTASGEKSIDLAGNATDQANGVQPAPG
                     TTSAENTQQDVSLPPISSTPTQGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVA
                     VNSTLPTEPATVAPVRNGNASRDTAKTQTAERPSTTRPARQQAVIEPKKPQATVKTEP
                     KPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGAKTA
                     GNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGV
                     YASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK"
     gene            complement(17942..19030)
                     /gene="aroB"
                     /locus_tag="RH288_000179"
     CDS             complement(17942..19030)
                     /gene="aroB"
                     /locus_tag="RH288_000179"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDV4029285.1"
                     /translation="MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNET
                     LAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVAL
                     GGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAA
                     RTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLIL
                     PLAIGKSEVRSGVSHELVLNAIADCQSA"
     gene            complement(19087..19608)
                     /gene="aroK"
                     /locus_tag="RH288_000180"
     CDS             complement(19087..19608)
                     /gene="aroK"
                     /locus_tag="RH288_000180"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HDV4029286.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            complement(20009..21247)
                     /gene="hofQ"
                     /locus_tag="RH288_000181"
     CDS             complement(20009..21247)
                     /gene="hofQ"
                     /locus_tag="RH288_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HDV4029287.1"
                     /translation="MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQE
                     KLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSIAWQNNNIA
                     RQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
                     KTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTT
                     LGSDLSVATATTHVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDG
                     KEDERRELVVFITPRLVSSE"
     gene            complement(21159..21563)
                     /gene="hofP"
                     /locus_tag="RH288_000182"
     CDS             complement(21159..21563)
                     /gene="hofP"
                     /locus_tag="RH288_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417851.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofP"
                     /protein_id="HDV4029288.1"
                     /translation="MRVKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGMV
                     GRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLTPDVLTLGTGTNCEPPQWLWQRQ
                     GDTNEAMDSRTTVDADTRRTGGKAAKSDADGG"
     gene            complement(21553..21993)
                     /gene="hofO"
                     /locus_tag="RH288_000183"
     CDS             complement(21553..21993)
                     /gene="hofO"
                     /locus_tag="RH288_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofO"
                     /protein_id="HDV4029289.1"
                     /translation="MNMFFDWWFATSPRLRQLCWAFWLLMLVTLIFLSSTHHEERDAL
                     IRLRASHHQQWAALYRLVDTTPFSEEKTLPFSPLDFQLSGAQLVSWHPSAQGGELALK
                     TLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG"
     gene            complement(21977..22516)
                     /gene="hofN"
                     /locus_tag="RH288_000184"
     CDS             complement(21977..22516)
                     /gene="hofN"
                     /locus_tag="RH288_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofN"
                     /protein_id="HDV4029290.1"
                     /translation="MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTG
                     SAEARIDAVLLQAEQQLARSLQITKPRLLEQQQLREQRSQRQRQRQFTRDWQSALEAL
                     AALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQ
                     GRWQFEYQLTRKVSDEHVL"
     gene            complement(22516..23295)
                     /gene="hofM"
                     /locus_tag="RH288_000185"
     CDS             complement(22516..23295)
                     /gene="hofM"
                     /locus_tag="RH288_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HDV4029291.1"
                     /translation="MAFKIWQIGLHLQQQEAVAVAIVRGAKECFLQRWWRLPLENDII
                     KDGRIVDAQQLAKTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQTAWL
                     SGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPD
                     ASALQRFLPFLPSHQQCLAWRDNEQWLWATRYSWGRKLAVGMTSAKELAAALSVDPES
                     VAICGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKAY"
     gene            23415..25967
                     /gene="mrcA"
                     /locus_tag="RH288_000186"
     CDS             23415..25967
                     /gene="mrcA"
                     /locus_tag="RH288_000186"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417855.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HDV4029292.1"
                     /translation="MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNN
                     KITDTLKALPTYGPLLPAAVTSANPQQATAMLADGSTVALSMEGVRWARPYRSDTQQG
                     PTPRKVTDVLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDASAGSDWQPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDT
                     QKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF"
     gene            complement(26133..26693)
                     /gene="nudE"
                     /locus_tag="RH288_000187"
     CDS             complement(26133..26693)
                     /gene="nudE"
                     /locus_tag="RH288_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HDV4029293.1"
                     /translation="MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRP
                     TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGF
                     GANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
                     DPDFNEARNVSALFLVREWLKGQGRV"
     gene            27013..29148
                     /gene="igaA"
                     /locus_tag="RH288_000188"
     CDS             27013..29148
                     /gene="igaA"
                     /locus_tag="RH288_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HDV4029294.1"
                     /translation="MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRK
                     LTPEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGIST
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETR
                     SYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFF
                     CLITPDVFVPWLAGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQE
                     QINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPL
                     QHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRV
                     GDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATAL
                     TEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLK
                     NALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARA
                     AQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNA
                     EGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQR
                     HRTRMMEIQAYYESCLNPQLITPSESLIE"
     gene            29213..29881
                     /gene="yrfG"
                     /locus_tag="RH288_000189"
     CDS             29213..29881
                     /gene="yrfG"
                     /locus_tag="RH288_000189"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HDV4029295.1"
                     /translation="MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNG
                     VTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFL
                     EALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
                     ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLI
                     PSLM"
     gene            29892..30293
                     /gene="hslR"
                     /locus_tag="RH288_000190"
     CDS             29892..30293
                     /gene="hslR"
                     /locus_tag="RH288_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HDV4029296.1"
                     /translation="MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMALAR
                     KLNALTMPHPDRRPDKKERRDLLRFKHGDSE"
     gene            30318..31196
                     /gene="hslO"
                     /locus_tag="RH288_000191"
     CDS             30318..31196
                     /gene="hslO"
                     /locus_tag="RH288_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDV4029297.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNV
                     LAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENA
                     DLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEV
                     TVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(31259..32983)
                     /locus_tag="RH288_000192"
     CDS             complement(31259..32983)
                     /locus_tag="RH288_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HDV4029298.1"
                     /translation="MDNVELSPATRWGMIATGLLQGLVCYLLIAWLSGKNHSWIVYGV
                     PATVAFSSVLLFSVISFKQKRLWGWLALVFIATLGMSGWLKWQTDGMNPWRAEKALWD
                     FGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLL
                     LWSELFKLVGITFFNTLFFATDWFIYLTLGLVTALAVILARTQSRLIDSIQKLFTLIA
                     TGLLPLVSLLTLMFIITLPFTGLSAISRHISAAGLLLTLAFLQLILMAIVRDPQKASL
                     PWTGPLRCLIKTALLVAPLYVFVAAWALWLRVAQYGWTVDRLQGVLAVLVLLVWSLGY
                     FVSIVWRKGQNPVVLQGKVNLAVWLLVLVILVLLNSPVLDSMRISVNSHMARYQSGKN
                     TSDQVTIYMLEQSGRYGRAALESLKSDAGFMKDPKRARDLLMALDGEQHLQQQVSEKV
                     LADNVLIAPGSVKPDATFWSALIQDRYNVMTCIEKDACVLVEQDLNSDGQAERILFAF
                     NDDRVIVYGFDSDRKEWDALDMSLLPNEITKEKLLTAAKDGKLGTKPKAWRDLVVDGE
                     RLNVNLNE"
     gene            33362..34984
                     /gene="pckA"
                     /locus_tag="RH288_000193"
     CDS             33362..34984
                     /gene="pckA"
                     /locus_tag="RH288_000193"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDV4029299.1"
                     /translation="MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGY
                     ERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETW
                     QHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
                     AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSM
                     MNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDD
                     GVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRV
                     SYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLA
                     GTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRI
                     SIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQE
                     KAETLAKLFIDNFDKYTDTPAGAALVAAGPKL"
     gene            complement(35060..36412)
                     /gene="envZ"
                     /locus_tag="RH288_000194"
     CDS             complement(35060..36412)
                     /gene="envZ"
                     /locus_tag="RH288_000194"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HDV4029300.1"
                     /translation="MRRLRFSPRSSFARTLLLIVTLLFASLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHP
                     LSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVR
                     GDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKEG
                     "
     gene            complement(36409..37128)
                     /gene="ompR"
                     /locus_tag="RH288_000195"
     CDS             complement(36409..37128)
                     /gene="ompR"
                     /locus_tag="RH288_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HDV4029301.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            37356..37832
                     /gene="greB"
                     /locus_tag="RH288_000196"
     CDS             37356..37832
                     /gene="greB"
                     /locus_tag="RH288_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026216.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HDV4029302.1"
                     /translation="MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCLENLKIVDYSPQQEGKVFFGAWVEIENDDGVTHR
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP"
     gene            37929..40250
                     /locus_tag="RH288_000197"
     CDS             37929..40250
                     /locus_tag="RH288_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417866.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDV4029303.1"
                     /translation="MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLSYLRELEERRQAILKSISEQGKLTDDLAKAINSTLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYVDADKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVSGKEEEGAKFRDYFDHHEPLSTV
                     PSHRALAMFRGRNEGVLQLSLNADPQFDEPPKESYCEQIIMDHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASR
                     ETERFYLDVQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETNARRGGGNERPQ
                     NNRPAAKPRGREAQPAGNSAMMDALAAAMGKKR"
     gene            40707..40934
                     /gene="feoA"
                     /locus_tag="RH288_000198"
     CDS             40707..40934
                     /gene="feoA"
                     /locus_tag="RH288_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HDV4029304.1"
                     /translation="MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALLEVEAVSC"
     gene            40951..43272
                     /gene="feoB"
                     /locus_tag="RH288_000199"
     CDS             40951..43272
                     /gene="feoB"
                     /locus_tag="RH288_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HDV4029305.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQ
                     FSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
                     LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAY
                     AGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDK
                     IVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSL
                     KDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIG
                     LLRRARSRVDIELLATRKSVSSCCAASTTGDCH"
     gene            43272..43508
                     /gene="feoC"
                     /locus_tag="RH288_000200"
     CDS             43272..43508
                     /gene="feoC"
                     /locus_tag="RH288_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HDV4029306.1"
                     /translation="MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMG
                     KAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR"
     gene            43711..44589
                     /gene="rpnA"
                     /locus_tag="RH288_000201"
     CDS             43711..44589
                     /gene="rpnA"
                     /locus_tag="RH288_000201"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnA"
                     /protein_id="HDV4029307.1"
                     /translation="MSKKQSSTPHDALFKLFLRQPDTARDFLAFHLPAPIHALCDMKT
                     LKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCLIEHQSTSNKLIAFRMMRYAIAA
                     MQNHLDAGYKTLPMVVPLLFYHGIESPYPYSLCWLDCFADPNLARQLYASAFPLIDVT
                     VMPDDEIMQHRRMALLELIQKHIRQRDLMGLVEQMACLLSSGYANDRQIKGLFNYILQ
                     TGDAVRFNDFIDGVAERSPKHKESLMTIAERLRQEGEQSKALHIAKIMLESGVPLADI
                     MRFTGLSEEELAAASQ"
     gene            complement(44618..45388)
                     /gene="bioH"
                     /locus_tag="RH288_000202"
     CDS             complement(44618..45388)
                     /gene="bioH"
                     /locus_tag="RH288_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HDV4029308.1"
                     /translation="MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHL
                     VDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQAL
                     VTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
                     LKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPML
                     DKLWPHSESYIFAKAAHAPFISHPAEFCHLLVALKQRV"
     gene            45426..46109
                     /gene="gntX"
                     /locus_tag="RH288_000203"
     CDS             45426..46109
                     /gene="gntX"
                     /locus_tag="RH288_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417872.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HDV4029309.1"
                     /translation="MLTVPGLCWLCRMPLALGHWGICSVCSRATRTDKTLCPQCGLPA
                     THSHLPCGRCLQKPPPWQRLVTVADYAPPLSPLIHQLKFSRRSEIASALSRLLLLEVL
                     HARRTTGLQLPDRIVSVPLWQRRHWRRGFNQSDLLCQPLSRWLHCQWDSEAVTRTRAT
                     ATQHFLSARLRKRNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAAAV
                     QVWCLCRTL"
     gene            46168..46743
                     /gene="nfuA"
                     /locus_tag="RH288_000204"
     CDS             46168..46743
                     /gene="nfuA"
                     /locus_tag="RH288_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HDV4029310.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            47103..48419
                     /gene="gntT"
                     /locus_tag="RH288_000205"
     CDS             47103..48419
                     /gene="gntT"
                     /locus_tag="RH288_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HDV4029311.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEE
                     MPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNI
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI"
     gene            complement(48530..50614)
                     /gene="malQ"
                     /locus_tag="RH288_000206"
     CDS             complement(48530..50614)
                     /gene="malQ"
                     /locus_tag="RH288_000206"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HDV4029312.1"
                     /translation="MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQR
                     TATKVAVTPVPNVMVYTSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPT
                     KLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
                     IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNA
                     VEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDE
                     QMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFC
                     EEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDREL
                     YCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHV
                     MSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGK
                     LRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGDLTLGKT
                     LGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRY
                     IADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWRRKLSATLESMFADDGVNKLLKD
                     LDRRRRAAAKKK"
     gene            complement(50624..53017)
                     /gene="malP"
                     /locus_tag="RH288_000207"
     CDS             complement(50624..53017)
                     /gene="malP"
                     /locus_tag="RH288_000207"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HDV4029313.1"
                     /translation="MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALA
                     EMLRAQPFAKPVANQRHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDL
                     LEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
                     DWHRSNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALERWEVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEK
                     VWAKLAVVHDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWIKQCNPALAALLDKSLQKEWANDLDQLINLEKFADDAKFRQQYREIKQANK
                     VRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     QVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAFDQMLHSIGKQGGDPYL
                     VMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            53629..56334
                     /gene="malT"
                     /locus_tag="RH288_000208"
     CDS             53629..56334
                     /gene="malT"
                     /locus_tag="RH288_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HDV4029314.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYG
                     KTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQY
                     ASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGW
                     ATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAI
                     LRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQW
                     ELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSL
                     LEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAE
                     FNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSL
                     ALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGD
                     LDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFA
                     NNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     AGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRI
                     LREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV"
     gene            complement(56377..57393)
                     /gene="rtcA"
                     /locus_tag="RH288_000209"
     CDS             complement(56377..57393)
                     /gene="rtcA"
                     /locus_tag="RH288_000209"
                     /EC_number="6.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
                     /protein_id="HDV4029315.1"
                     /translation="MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAK
                     PGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVL
                     QTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFY
                     PAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSL
                     HEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLAS
                     TAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFSLIETDGVTR
                     VSIE"
     gene            complement(57397..58623)
                     /gene="rtcB"
                     /locus_tag="RH288_000210"
     CDS             complement(57397..58623)
                     /gene="rtcB"
                     /locus_tag="RH288_000210"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-splicing ligase RtcB"
                     /protein_id="HDV4029316.1"
                     /translation="MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIA
                     VMPDVHLGKGSTIGSVIPTKGAIIPAAVGVDIGCGMNALRTALTAEDLPENLAELRQA
                     IETAVPHGRTTGRCKRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHL
                     GTLGTGNHFIEICLDESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRD
                     LAYFMEGTEYFDDYLKAVAWAQLFASLNRDAMMENVVTALQSITQKTVRQPQTLAMEE
                     INCHHNYVQKEQHFGEEIYVTRKGAVSARAGQYGIIPGSMGAKSFIVRGLGNEESFCS
                     CSHGAGRVMSRTKAKKLFSVEDQIRATAHVECRKDAEVIDEIPMAYKDIDAVMAAQSD
                     LVEVIYTLRQVVCVKG"
     gene            58812..60410
                     /gene="rtcR"
                     /locus_tag="RH288_000211"
     CDS             58812..60410
                     /gene="rtcR"
                     /locus_tag="RH288_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RtcR"
                     /protein_id="HDV4029317.1"
                     /translation="MRKTVAFGFVGTVLDYAGRGSQRWSKWRPTLCLCQQESLVIDRL
                     ELLHDARSRSLFETLKRDIASVSPETEVVSVEIELHNPWDFEEVYACLHDFARGYEFQ
                     PEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQSSPPRKKEQPRGPGEVTIIDLD
                     LSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTG
                     AGKSFLARRIFELKQARHQFSGAFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREG
                     LLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPFGSDRQVSSDFQLIAGTVRDL
                     RQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHASLTGDSVRFNTE
                     ARRAWLAFATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQES
                     RPSALTALLGAEAENIDLFDRMQLEHVIAICRQAKSLSAAGRQLFDVSRQGKASVNDA
                     DRLRKYLARFGLTWEAVQDQHSSS"
     gene            complement(60392..61150)
                     /locus_tag="RH288_000212"
     CDS             complement(60392..61150)
                     /locus_tag="RH288_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HDV4029318.1"
                     /translation="MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELA
                     EQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTT
                     PEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
                     SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC"
     gene            complement(61167..61997)
                     /gene="glpG"
                     /locus_tag="RH288_000213"
     CDS             complement(61167..61997)
                     /gene="glpG"
                     /locus_tag="RH288_000213"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HDV4029319.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQ
                     AERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMI
                     ACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
                     "
     gene            complement(62042..62368)
                     /gene="glpE"
                     /locus_tag="RH288_000214"
     CDS             complement(62042..62368)
                     /gene="glpE"
                     /locus_tag="RH288_000214"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HDV4029320.1"
                     /translation="MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLT
                     NDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPA
                     EVAYGA"
     gene            62558..64063
                     /gene="glpD"
                     /locus_tag="RH288_000215"
     CDS             62558..64063
                     /gene="glpD"
                     /locus_tag="RH288_000215"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HDV4029321.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGM
                     HLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE
                     GDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGTVSDLGEDFGHEFYEAE
                     LKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQWLVEYTQQRLSLAS"
     gene            complement(64332..64553)
                     /locus_tag="RH288_000216"
                     /pseudo
     CDS             complement(64332..64553)
                     /locus_tag="RH288_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312299.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
     gene            complement(64679..67126)
                     /gene="glgP"
                     /locus_tag="RH288_000217"
     CDS             complement(64679..67126)
                     /gene="glgP"
                     /locus_tag="RH288_000217"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HDV4029322.1"
                     /translation="MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGAL
                     EAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQ
                     IIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRL
                     LIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNELQQHCD
                     FPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEML
                     DHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDR
                     TIKEYADHIWHIDPVRL"
     gene            complement(67145..68578)
                     /gene="glgA"
                     /locus_tag="RH288_000218"
     CDS             complement(67145..68578)
                     /gene="glgA"
                     /locus_tag="RH288_000218"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDV4029323.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAF
                     PDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFA
                     YTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAEN
                     KRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            complement(68578..69873)
                     /gene="glgC"
                     /locus_tag="RH288_000219"
     CDS             complement(68578..69873)
                     /gene="glgC"
                     /locus_tag="RH288_000219"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDV4029324.1"
                     /translation="MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVF
                     DADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRD
                     VGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER"
     gene            complement(69891..71864)
                     /gene="glgX"
                     /locus_tag="RH288_000220"
     CDS             complement(69891..71864)
                     /gene="glgX"
                     /locus_tag="RH288_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HDV4029325.1"
                     /translation="MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQE
                     HRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDG
                     EFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKG
                     LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNY
                     WGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPL
                     FSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFR
                     FDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEW
                     NDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDC
                     VCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVE
                     NRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPA
                     GEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR"
     gene            complement(71861..74047)
                     /gene="glgB"
                     /locus_tag="RH288_000221"
     CDS             complement(71861..74047)
                     /gene="glgB"
                     /locus_tag="RH288_000221"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HDV4029326.1"
                     /translation="MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDAT
                     DVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETAS
                     LICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVIL
                     DWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALY
                     WIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQV
                     SGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLT
                     FGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPY
                     GFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTD
                     SMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE"
     gene            complement(74320..75423)
                     /gene="asd"
                     /locus_tag="RH288_000222"
     CDS             complement(74320..75423)
                     /gene="asd"
                     /locus_tag="RH288_000222"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDV4029327.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAA
                     PSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLR
                     MKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
                     YQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNF
                     GVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQ
                     AFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRK
                     LNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            75616..76209
                     /gene="yhgN"
                     /locus_tag="RH288_000223"
     CDS             75616..76209
                     /gene="yhgN"
                     /locus_tag="RH288_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YhgN"
                     /protein_id="HDV4029328.1"
                     /translation="MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVREL
                     LIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAG
                     EEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
                     RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG"
     gene            complement(76266..77606)
                     /gene="gntU"
                     /locus_tag="RH288_000224"
     CDS             complement(76266..77606)
                     /gene="gntU"
                     /locus_tag="RH288_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HDV4029329.1"
                     /translation="MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAH
                     YAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
                     GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(77610..78137)
                     /gene="gntK"
                     /locus_tag="RH288_000225"
     CDS             complement(77610..78137)
                     /gene="gntK"
                     /locus_tag="RH288_000225"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDV4029330.1"
                     /translation="MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHP
                     RRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPL
                     EGVVASTIEVIKKGK"
     gene            complement(78276..79271)
                     /gene="gntR"
                     /locus_tag="RH288_000226"
     CDS             complement(78276..79271)
                     /gene="gntR"
                     /locus_tag="RH288_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HDV4029331.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSKSPCLDIAV
                     GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVE
                     QSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI"
     gene            complement(79495..80190)
                     /gene="yhhW"
                     /locus_tag="RH288_000227"
     CDS             complement(79495..80190)
                     /gene="yhhW"
                     /locus_tag="RH288_000227"
                     /EC_number="1.13.11.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="HDV4029332.1"
                     /translation="MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVIN
                     DDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHS
                     EYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHAD
                     SDSEVLLFDLPPV"
     gene            complement(80313..81350)
                     /locus_tag="RH288_000228"
     CDS             complement(80313..81350)
                     /locus_tag="RH288_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDV4029333.1"
                     /translation="MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQ
                     APIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTL
                     AQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGD
                     LKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGV
                     LEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKESEVLTNLEILERGFE
                     QASPSTVTLAK"
     gene            81683..82171
                     /gene="yhhY"
                     /locus_tag="RH288_000229"
     CDS             81683..82171
                     /gene="yhhY"
                     /locus_tag="RH288_000229"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV4029334.1"
                     /translation="MSEIVIRHAETRDYEAIRQIHAQPEVYCNTLQVSHPSDHMWQER
                     LADRPGIKQLVACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMRE
                     MIEMCDNWLRVDRIELTVFVDNAPAIKVYKKYGFEIEGTGKKYALRNGEYVDAYYMAR
                     VK"
BASE COUNT        19645 a        22556 c        20812 g        19219 t
ORIGIN      
        1 tttattaaag ttgcactggt aggtgcagta ctggctacgt taactgcatg tactggtcat
       61 attgaaaacc gtgataagaa ctgctcttac gactacctgc tgcacccggc aatttctatt
      121 tctaaaatca ttggcggttg cggtcctact gcacagtaag tctctgacag aaatcggcta
      181 acaccggttt aattgcccga cgccctctgg attttccgag ggcgtatttg tttctatgtc
      241 cttcttgccc ccgcccgtaa aaatattttc actttaaatt caatttgata actacatcca
      301 ttagccacag cgcgatcctg tgcgaaattt tgtgatcttc ctccacatta cataacatca
      361 tatgttgtta tattcatcat gcattgtcat gttacctttt aaatgactgc aaactctccc
      421 ctacaacgta ttggacaaga aaaaggtatc gctatgggaa gccaggaact ccaacgcaag
      481 ctcggatttt gggccgttct tgcaatcgcc gtcgggacaa ccgtcggctc cggtattttt
      541 gtatctgtgg gtgaagtggc aaaagcagcg ggcacgccgt ggcttacggt gctcgcgttt
      601 gtcattggcg ggttaattgt gatcccgcaa atgtgcgtct atgcggaact atccaccgct
      661 tatccggaaa atggcgcaga ttatgtttat ctgaaaaatg ccggaagccg accgctggct
      721 ttcctctccg gctgggccag cttctgggcc aacgatgcgc cgtcattgtc gattatggcg
      781 ctggcgattg tcagcaatct tggcttttta acgcctatcg atccgttgct cggtaaattt
      841 atcgccgccg gattaattat cgcctttatg ttgctacacc tgcgctccgt tgaaggcggc
      901 gcagcgtttc agacgctaat taccatcgcc aaaattatcc cgttcactat cgtcattggc
      961 cttgggatct tctggtttaa agcggagaat tttgccgccc ctaccaccac tgcgattggc
     1021 gcaacgggca gctttatggc gctgctggcg gggatctctg ccaccagttg gtcgtatacc
     1081 ggcatggcct ctatctgtta tatgaccggc gaaattaaaa accccggaaa aaccatgcca
     1141 cgagcgctga ttggttcctg tctgctggtt ctggtgctct acaccctgct ggcgctggtg
     1201 atttccggcc tgatgccctt cgacaaactc gccaattctg aaacgccgat ttccgacgcc
     1261 ctgacctgga tccccgcact cggcagcacc gctgggatct ttgttgccat cacggcgatg
     1321 atcgtcattc ttggttcgct ttccagctgc gtgatgtacc agccgcggct ggaatacgcg
     1381 atggcgaaag acaacctgtt ctttaaatgc ttcggccatg tgcatccgaa atacaacacg
     1441 ccggatgtct ccatcatcct gcaaggggcg ctggggatct tcttcatctt cgtttccgat
     1501 ctcaccagcc tgctgggtta tttcaccctg gtgatgtgtt tcaaaaatac cctcaccttc
     1561 ggctccatca tctggtgtcg taaacgcgac gattacaaac cgctgtggcg tactccggct
     1621 ttcgggctga tgaccaccct cgccattgcg tcaagcctca ttctggtcgc ctcaaccttt
     1681 gtctgggcac cgattcccgg ccttatctgc gccgtcatcg ttattgctac tggtctgcct
     1741 gcttacgcct tctgggcgaa gcgtagccgc cagctcaacg ctttgtcgta atgttatctg
     1801 gagaaaataa aatgttggat attgataaaa gcaccgtgga ctttctggtc accgaaaata
     1861 tggttcagga agtggaaaaa gttctcagcc atgacgttcc gctggtgcac gccatcgtgg
     1921 aagagatggt gaagcgcgac attgatcgta tttatttcgt tgcctgcgga tcgccactca
     1981 acgcggcgca aacggcgaaa catctggcgg atcgcttttc cgatcttcag gtctacgcca
     2041 tttccggctg ggagttctgc gataacaccc cgtatcgcct cgacgatcgt tgcgcagtaa
     2101 ttggcgtttc tgactacggt aaaaccgaag aggtaatcaa agcgctggag ctgggccggg
     2161 cctgcggcgc actcactgcg gcgttcacca aacgcgcgga tagcccgatt acctcggcgg
     2221 cggaatttag cattgattat caggccgact gtatctggga aattcacctg ctgctctgct
     2281 acagcgtggt gctggagatg atcacccgcc tcgcgccgaa cgcggaaatc ggcaagatca
     2341 aaaacgatct caagcagttg ccgaatgcgc tcggtcatct ggtacgcacc tgggaagaaa
     2401 aaggccgcca gcttggtgaa ctggccagcc agtggccgat gatttatacc gttgctgcgg
     2461 gtccgctgcg tccgctgggt tacaaagaag gcattgtaac gctgatggaa tttacctgga
     2521 cgcacggctg cgtgattgag agcggagagt tccgccatgg cccgctggag attgtcgaac
     2581 cgggcgttcc gttcctgttc ctgctcggca atgatgaaag tcgccacacc accgaacgcg
     2641 ccattaactt tgttaaacag cgtactgaca acgtgatcgt catcgattac gccgaaattt
     2701 cgcaagggct gcacccgtgg ctggcaccgt tcctgatgtt cgtgccaatg gagtggctct
     2761 gctactacct gtctatttac aaagatcaca acccggatga acgccgctat tacggtggtc
     2821 tggtggaata ttaatccctc tcccggcccg gcaacgggcc ggatttacgc aaggagttac
     2881 ccgatgaaaa caggtatgtt tacctgcggc caccagcggc tgcctattga acacgcattt
     2941 cgtgatgcaa gcgagctggg ttacgacggc atcgaaattt ggggcggtcg cccgcacgcg
     3001 ttcgcgccgg acttaaaagc gggcggcatc aaacaaatca aggcgctggc gcagacgtat
     3061 cagatgccga ttatcggcta tacgccagaa accaacggct atccgtataa catgatgctg
     3121 ggcgatgaac atatgcgtcg cgaaagcctc gacatgatca agctggcgat ggatatggca
     3181 aaagagatga acgcgggtta tacgctgatt tccgcggccc acgcgggcta tctcacgcca
     3241 cctaatgtta tctggggacg gctggcagag aacctaagcg aactgtgtga gtacgcggaa
     3301 aacatcggca tggatctaat cctcgaaccg ttaacgccgt atgaatcgaa cgtcgtgtgt
     3361 aatgctaatg atgtgcttca tgcgctggcg ctggtgcctt cgccgcgcct gttcagcatg
     3421 gtcgacattt gcgcgccgta tgtccaggcg gaaccggtga tgagttattt cgacaaactg
     3481 ggcgataaat tacgtcatct gcatattgtc gacagcgacg gggccagcga cacgcattac
     3541 attcctggag aaggcaaaat gccgctgcgg gaactgatgc gcgatattat tgagcggggc
     3601 tatgagggtt actgtacggt ggagctggtg acgatgtata tgaacgagcc cagactctat
     3661 gcccgccagg cgctggaacg ctttcgcgcg ctgctgccgg aggatgagag atgaaaaccc
     3721 tggcgacaat cggcgataac tgcgtcgata tctacccgca actgaataaa gcgttttctg
     3781 gcggtaatgc ggtcaatgtg gcggtgtact gcactcgcta cggcatacag ccgggatgca
     3841 ttacctgggt gggtgacgat gactacggca caaagctgaa gcaggatctc gcccgcatgg
     3901 gcgtcgatat cagccatgtc catacgaaac acggcgttac cgcacaaact caggtggaac
     3961 tgcacgacaa tgatcgcgtt tttggcgact acaccgaagg cgtgatggcc gactttgccc
     4021 tgagtgaaga ggattacgcc tggctggcgc agtatgacat tgtgcacgcg gcaatctggg
     4081 gacatgcgga agacgcattc ccacagctgc acgctgcggg caaacttacc gctttcgact
     4141 tctccgacaa gtgggacagc ccgctctggc agacactggt gccgcatctc gattttgcct
     4201 ttgcctccgc accgcaagaa gacgaaacgc tgcgtctgaa gatgaaagcg attgttgccc
     4261 gtggcgcagg aacagtgatt gtcacgctgg gtgaaaacgg cagcattgcc tgggatggcg
     4321 cgcagttctg gcgtcaggct cctgaaccgg tgacggttat cgacaccatg ggtgccggag
     4381 attcgttcat tgccggattc ctttgcggct ggtctgcggg gatgacatta ccgcaggcga
     4441 tagcgcaggg aacggcgtgc gcggcgaaaa ccattcagta ccacggtgcc tggtaggtat
     4501 aacgttggcg tgagcatctt cacgccaacg tgctgttact tgccggaaaa cgaccctata
     4561 atccgagtaa ttcattcttt atttcagggt cgattatgtc agctacggac cgctactctc
     4621 atcaactcct ctacgctacc gtccgccagc gactgctgga tgatatcgcg cagggggttt
     4681 accaggccgg gcaacagatc cctaccgaaa acgagctttg tacacaatat aacgtcagcc
     4741 gcattaccat tcgcaaagcc atcagcgact tagtggcaga cggcgtactg atccgctggc
     4801 agggaaaagg cacctttgta caaagccaga aagttgaaaa cgccctgctt actgtcagtg
     4861 gttttaccga tttttgcgtc tcacaaggca aggcgacgaa agagaaagtg atcgaacagg
     4921 aacgggtcag cgccgcgccg ttttgcgaaa agctgaacat ccccggaaac agcgaagtgt
     4981 tccatctctg ccgggtgatg tatctcgata aagagccgct gtttattgat agttcatgga
     5041 tcccgctgtc gcgttatcct gactttgatg agatttacgt cgaaggaagc tccacctatc
     5101 agttatttca ggagcgtttt gacacgcgag tggtcagcga caaaaagacc atcgatatct
     5161 ttgccgccac ccgcccgcag gcaaaatggc tgaaatgcga actgggcgaa ccgttgtttc
     5221 gcatcagcaa aatcgccttt gatcagaatg acaaaccggt gcacgtctcc gaactcttct
     5281 gccgcgccaa tcgcatcacc ttaactattg ataataaaag acattaaccg taggccggat
     5341 aagatgcgcc agcatcgcat ccggcgatgc tggcgcgttg aattttacat cccgtacgtt
     5401 cccctcaccc taaccctctc cccaaagggg cgaggggacc gttcagtacg gaatttagct
     5461 tgacggtgct atccagcatt aaatactggc aatactctca cgcaaaatcc gcagcaccgt
     5521 ctcttcaccg ctgcgattcg ggttaatgcg aatcgcacaa tgttctgatt gtggattcgc
     5581 ctggcgaaac gttccggaaa ggcgataaaa gagcggcggg atttcatatt tcgactctgc
     5641 acccaccggg taaggcaagg caccgcgctt ttgcgcctct tccagcactc tggcggcaat
     5701 cggctgatga aactcgacaa tcaacacctt cgactgcgca ttagcaatca ccgcgctttt
     5761 cacttccggc accgcaccac cgttaagcaa agccagcaac cgttcagata cccctgcctg
     5821 caccgcgtgc atcactggcg caaacaccag accacgcaat acttccagcg cctgtgcgcc
     5881 ctggatctgg ctaccgccgg agtaaagcgt ggcgcgaata cggttgataa catcagcatc
     5941 gccgaccact gcaccaacac cctctggccc aaatagcttg aagcaggaaa atgtcgagac
     6001 attcgcgccg cattcacagc cgattcgagc caccttcatc accgcatagt tgtcatcggt
     6061 taacgctgga acacctgccg cgcgcaacgt tgccagcaca tctgccagca cgtagctgtc
     6121 ctgcggctgc tggcgcgtat gctgcaccag cgccgcatcc ggttgttgct cgtcgacgac
     6181 ctgcttcagt gccgacaggt cattgaaatc aacagtaata agcgtcagcc ccatctgctc
     6241 aataataacc cgtgtcgtcg ggtaaacagg cgcgtcatgc accagaagac gctgccccgg
     6301 tttgagcaaa gccgccagcc cggcgcgaat cgcgccagtc cccgcgccct gcaccagcgc
     6361 cgcagcctgt gcgtgaaatg catcagccag cacctgttcc acacgctggg taacgcgcgg
     6421 ttgattcagt cctggcgtta agcctaaatc accgccagta agaaactcgc tgccggggaa
     6481 atggcgacaa atgctatcca ccagcgcaaa ctgcttttgc tgcgcctcaa taatcgtcag
     6541 gctttgcaga ggaaacgtct tcataggtgc cttccttaag ccggaacgaa caggccaagc
     6601 cagtaaagaa cattcagcag aataccggtg atcattactg ccacgaccgg tgccgccatt
     6661 ttctgtaccg gacggcccag ggattcgttg aggaagtaaa tggcaaccgc gatagagaat
     6721 ccggtataac ccgccatctt aattgctgcg aaaatcgaac cgaccagcag cgccacttcc
     6781 atcagcatat tcatggcgtt acggatgtta tccgacgcat tacgcaccga cgggtagcgt
     6841 cccagccatt tgccgatcga acgaagcagc aagacttccg ccgaaataac cactgcgcct
     6901 aataccgctg caaccatcgg attcggcgag agatagccca ccgcataaac aaaggtaaag
     6961 cccgcaactg catacacacc cgttgctaac gcggtggtgg caatcaacgg cacaaacccc
     7021 agtccgcgca taaattctgc cagagccgcc tgattaatca gcgtttgcga ttgttccggc
     7081 gttacgcctg cggaatatgc tttctccagt gtgaagatcg acacttcact gccagcaaaa
     7141 atcttcatgc tggcaacggc ggcaatcaat gctcccacta tggcgatata gggtaagttt
     7201 ttgataatcc gtgacgtgcg ttcttcaaac accgaaagcc cgctggcatc aatgtcattt
     7261 tcatcacgat gacgcaggtc gtgagttatc gcgatcccca gcagcatcac catgccaata
     7321 aagatttcga tggattcagg gttaagatgt gggaaatagc gcacgactac cacacgggtc
     7381 atcagtacca ccacggcggc gatcagactt tgcttccagc caaactggta gaaaatcgcc
     7441 accagcggga acagtgcaaa agctgaaacc accggcgagc ttaattcccc caggctacct
     7501 aatacatcca ccggcagcgc ggtcagcagc tggtttactg gcaacaggca agtaaggatc
     7561 aacacgcccc agatagcgcc aagaccaaac gccatcaggc tgtttatcgc caggacgccg
     7621 aggatatcgg taggaagaaa gagtaaccat gcgttgagca gcccggtttt cagggtaaaa
     7681 gagatcccca ccgaggccac aaaaccaatg ctcagaccaa aagcgatact ccccgcctcg
     7741 cgacggttca tatagccttc aatcagttgc ggcaggatcg ggcggatgcc gtcatgaaaa
     7801 acagccgccg agcgatgcgc cagaagcgat gtcatacccg tcaggcacgc caccacgata
     7861 atctgaatat acagatccat agtcgtgcct tttatttcag atggttaatc agcatcggaa
     7921 tcgcgtgttc gacgtgctca acggaaaggc caaacgccac ttttccttca gcgatcattt
     7981 tggcgatatg ctcgtctttc gctttaatgc ctggtttggc aatggtgcaa cttttgttat
     8041 agcctatcac cgcgatggca atcgacaatg ccgcgcccgc accggtatta cacgcgccga
     8101 tgtaataatc cagttgcccg gatttcacct tcattgccgc ttccatgtcg ttgtgaatga
     8161 aaacttcaaa acagccagga gccgtcgctt caatagtttt tttaatctgc tcacgctgta
     8221 agcctgcaac gccaatcttt ttcatgagtc tgtccttatt ggaaaaattg agagggattt
     8281 tcacgtaaca tcacatccac atcggcctga ctgaatcctg actggcgcaa ttgcggaata
     8341 aaggtggtta gtaaatagtc atagccataa ccaccgttgg cttttaaatg ggagcggcgc
     8401 gtaatatcca tcgacagcat gacgcggttc agcaacccac ggtcgcgtag cgcatgaagc
     8461 atcgcaatac gcttttcgtc cgggtagtaa ctgttcttgc cgatggtgtc gaactgcacg
     8521 tacgcgccga gatcgatcat cttcaaaatg ttgtcaaggt tgtctttcag atcgcagtga
     8581 ccaacggtga cgcgcgaaag atcaaccccg tgggcttgta gcaacgccag ttgctccagc
     8641 cccatcgtgc tgaacgacgt atgcgtggag atcgggcgtc cggtctggtt atgcgccagc
     8701 gcagcggcaa taaatacctt ctcttccagc ggcgtaatct ttccttcgct ggtgccgatc
     8761 tccgcgatga tcccggcttt cagctccgtg ccatcgatac cctgttcaat ttcatcgacc
     8821 atctcctgcg ccagttcctg cacgctgcgg gtcgccacat gttccgggaa aaacgcgtcc
     8881 tggtaataac cggtacaggc caccacgttg atccccgtct cgcgcattac atcaagcata
     8941 aattgcgcat tgcgccccat gtaacggttg gtcatctcaa tcacattacg cacgccccgg
     9001 gtcatcaggt cgttcatctc ctggcaaatg aacgcatact gatcaaggcg gcagtccacg
     9061 ttgtttttaa agccggagag atcaatatgc agatgctcat gggcgagggt gtaacccgtc
     9121 ggatcaaaac tcatagggtg tctcctgcaa accggaggga ggaaagaaaa gagcgaccat
     9181 tttgtggcgg tggcgcgcgg aaaaattcac acacggtagc ccccacatca gaaagcgtgg
     9241 tgcgcacacc gagctgcgta gcgatcatcc cttgctgata aaccagcact ggcaccactt
     9301 cgcgggtatg gtggctgtga ccaatggtcg gatcgttgcc gtgatccgcc atcacgacca
     9361 ggcaatcatc tggctgcatc gcctcaacaa gccgggcaag gttacggtca acgacctgca
     9421 aacgttcggc ataacgtgcg acgtcttctg catgaccagc gaggtcggtt tcctgaatgt
     9481 tggtgcaaat aaacgccgtc ggatgggtgt taaattcgtt gagggtgata tccataatcc
     9541 gctggctatc caccagattt tgccagctca cgccataagg attgttgacg atatctgcca
     9601 ccttacccac cagcacggtt ggcacgcctg cttcatacag tttttgtggc acctgcactt
     9661 tttcatcgac gccatagccc atatgcacga cctggaaacc gttgtcataa gcgccagaac
     9721 gcggcgcatt gataccaata aagcgccctt ctttgctttc tgcggcatcg agaatgcgtt
     9781 gactgtcggt taacaggcca ccaaatgtaa tgacccgacc gacctgtacc tgctcacgca
     9841 cgatacgacc aattttgatt gcgtcgtcaa aagagatcac agagagattg gcggtaatgt
     9901 tatagacctg gcctaaatcc gcctcgagat tatcgccaat cgcaaccgcc tgattgaccc
     9961 acagaaattg cagatcatcg ccacggcgct ccacctgcca gccagcggaa actaatgcct
    10021 gctcaacacg gtcaatcaca tcgcgaaaag gcatccgcag cggcggtaac gggcgcgtgc
    10081 ctaaaatttc ctgatgcccc ataaaggtat cgccaccttc atgttgcagc tctgccacgc
    10141 cccaggttgc ggaatctgac ggctgcatat cgcctggcgc ataacccaat gcgttgatta
    10201 gccccagctt ctccagcgtt ggtagctgca aatgcggcaa ctggctcagg atgtgaccac
    10261 atgtattcgc tcccgcatct tgcggacgca ccagcgtgac atctttcatt gcccctacgc
    10321 caaagctatc aatcactaac accacaaatc gcgccattac gcccccagag agtttccaag
    10381 actgtcataa cgaccgacga tttccggttc gccacgatga ataccggaca ccagcaccac
    10441 atcgctacgg gtgacaaaaa tctgcgtgcg aaaacagagc accactgcac tgcttaccgg
    10501 aaactcgcct gccagcggca gggtgtagtc gatactgctg tcatccacag ttttgagatt
    10561 ggtttcagta atcttttgat tttctggcgt aaacaccaac gcatgttgcg catgaccacg
    10621 acgatagtaa ccgccgccgt agcagtagct gtcgccacgg aaatgatggg agatttcact
    10681 taaccagagc atcgcgatac gttcaggctg atcgccctgc tggtttgccg gaatagtgcc
    10741 cgtcagcgca tgaccgggtt cggcatgagt cacaccgtat tgcgccagta atggcagcga
    10801 agtgcagctg gtcgctgaag gcgcgttcag ttgctcaagt gcaataccag atttcgccag
    10861 ttgatcccgt gcctgtatca gcgtgtgaag attcggtgtc ggcaaaactt ttccgacagc
    10921 ctcatcccaa agcaggcaag ggaaatgggt aagtccggct aaatgcagcc ctggcagatt
    10981 ctggatttcg gcgacaatct ccggcaacac cttgagggca aaaccgctct cctggcccgg
    11041 ataaagaaaa tcatcgtcgc tataaacttt aagcagcaca gactggattc gcccggcctt
    11101 caccgccgcc gcagaaactt cccgcgcttt gtcgagagta aacacggtga tgacgtcggt
    11161 gccctgttca acggcgtcag caacctgatg acaagggatt tgtaccagat gcccctgatg
    11221 cgccacaggc aaaccagcgc ggcgcatgac tcgcgcctct ttgtaatcca ccgccacaat
    11281 gccgctgtag cctaatgcca gcaatttttc cgccagccac ggattacgac caaactgctt
    11341 ggtcatcaga tacagttcaa tgccgtaaag ccgcgccgtc tcaatcagcc gcttaccgtt
    11401 ttccagtatc tgatccacgt cgatcaccca gctgtccggg gcgatcttgc cctgctgcca
    11461 caggcttagt gcggcggaaa tcagcgccgg gttctggcgt ttcaatgctt ctacaaacat
    11521 cttgttgcct cgtttctgtt ccttgaatta aatattcatt tttttgaata tttaggttgt
    11581 gcgacgtgga tttgtcggga gcttcaaacc tcttcgttag cagccatcca taatccataa
    11641 aggttggcca gcaaatagcc ttcttcacac gggttaactt ccagtgcgaa ttccttcaac
    11701 aacacctgat gcaattgcac aacggcttgc cagtggctgg attgcgccag ttctgccagc
    11761 aactcgttat ccagcggctc tatttcttca ccacggcgac tgcgcatcag tgcactcgcc
    11821 atatgtgtca tcgccatcgt tccttgctca ctgcgcaccg gcagatggca ctctgtttcc
    11881 agtacgttga cgacctgcat catgcctttg cagatgtcct tatcaataac gcctgcctcg
    11941 caaagcaggt tgagtctggt ttccatatca gatgcctttc gtttaataac tcggttcctg
    12001 ttccccactc actacccgtt gttgatgggc gagcagggcg tgtttatcta caacggcacg
    12061 cagcagttgt tgcattgggt aatcatcgac tcgcgtcagg accacggctt cggtggcctg
    12121 taaaaatcgc ggatcgtctg tgagcggcgt cgcctctaat cccagcatgg tcagttcgtt
    12181 ttccgccacc acgttccaga tcaccgcatc gacatcgcct ttaacaatgc gttgtaaact
    12241 ctcgtgataa gagagatcga ctcgttccac atcactaccg ccaaaaaaaa catcggtcat
    12301 gattttctga tccgccgaac ggttatccag ccccacgcgc ttcacgtttg cggactcgcc
    12361 tttacggcaa atcaactggt gctcgccaac gtaggtgtgc ggccccaact ccagcgcgag
    12421 gcataagcct ttttgcgtga gataactttc cgccgctagt cgcgaaacca ccgccatgtc
    12481 atacacgcca ttaagcagac actccacgcg aatatccgcg ccacgcatgt gcgcatagta
    12541 aaaaggaatg ccatcaaact gggctttcaa tccgctcgcc aggccttcgt acaaacgggt
    12601 atagggcaag ggcattgcac ataccacgtt gttgatatcc acatgagtca gcaatgcttt
    12661 gttatccatc tcgaccagat aactgccatt gcgcccacgg cgttcaatcc gtatcgctcc
    12721 gcttgattcc agcgttttca acgcggcctg cgtcaggcca acggatgaac ggcattcatt
    12781 tgccagctca tctatggttt tcaatcgatt accgcacttt tcacccaaca aataacgggc
    12841 cagcgtcgtg atgacgacgc cttctttttt gataaacgtt cgacgcataa taaattttca
    12901 gtaaattgaa tatttatatc ttcaggaatt tgaagataag gcgcaacagc gagatgtgga
    12961 aacggcgagg cacttcacat tttttcggat tattgcaaat gaggataaaa aaaccgggtt
    13021 tccccggttt cagagtgatg ataaaagcaa aattgcctga tgcgctacgc ttatcaggcc
    13081 tacatttcct tgcaatatgt gcattacttt gtaggccgga taaggcgttc acgccgcatc
    13141 cggcatgaac aaagcgcaat ttgccagcaa tagtgaatta cggcttcgcc acaaaaccaa
    13201 tcgcttcgta caccgctttt agcgtacggg aagcgtgcgc gctggctttt tccgcgccat
    13261 ctttcatcac ctgttgcagg aaggcttcat cgttgcggaa acggtgatag cgttcctgca
    13321 attcagtcag cataccggaa acggcatcag ccacttcacc tttcagatga ccatacatct
    13381 tgccttcgaa ctgtttttcc agttctggga tgctctggcc cgttaccgct gaaaggatat
    13441 ccaacaggtt ggaaacgccc gctttgttct gcacatcgta gcgaactacc ggcggctcgt
    13501 cggagtcagt gaccgcacgt ttgattttct tcactaccga tttcggatct tccagcaggc
    13561 cgataacgtt attgcgatta tcgtcagact tggacatctt cttggtcggc tccagcagcg
    13621 acattacgcg cgcgccagat ttcggaataa acggctccgg caccttaaag atctcgccat
    13681 acagcgcgtt gaaacgctgg gcaatatcgc ggctcagttc gaggtgctgt ttctggtctt
    13741 cacccaccgg taccagatta gtttgataca gcaggatgtc cgctgccatc agcaccggat
    13801 agtcaaacag accagcgttg atgttctcgg cataacgcgc agatttatct ttaaactgcg
    13861 tcatgcgact cagttcgccg aagtaggtat agcagttcag tgcccagcct aactgtgcat
    13921 gttccggcac gtgggactga acaaaaatgg tgcttttctc aggatcgata ccacaagcca
    13981 gatacaaggc cagcgtatcc agcgtcgctt tacgcagctt ctgtgcatcc tggcgcacgg
    14041 tgatcgcgtg ttggtcaacg atacagtaaa tgcaatggta gtcatcctgc atgtttaccc
    14101 actgacgcag cgcacccatg tagttaccaa tggtcaattc acctgagggc tgtgcgccac
    14161 taaaaacgat gggcttagtc atttttcgat tcctgatttt cgctatgcgg aagccctaat
    14221 gcgggcagaa ggtcatttat agactgataa attacatcag gctggctgag atcgatagcc
    14281 tcgccgtagt tatatccgta ggttaagcca actgatgggc aacctgccgc ttttgccgcc
    14341 tgaatatcat tgcgtgagtc gccgacaaac agcatctgtt gtggggcaat tcccatccgc
    14401 tcagccacca gtaacagcgg gtccggatgc ggttttttgt tttgcacatc atcaccacca
    14461 atcaccacgc tgaagtattt ggcgatatct aaggcttcga gcagcggcgc gacgaacggc
    14521 gtcggtttgt tggtgaccag gcctagcggc aggcctttag cctgcaacgc gcccaacgta
    14581 tcggcaacgt gcgggaacaa aaacgtcccc tcttcggcaa cctcgccata gtagcgatcg
    14641 aacagtttac gcagaatacg tacctgttct tctgccggaa tgtcgtcatc aacgggcggt
    14701 ttacccattg ttttacgctg agtcgcacgt tcctgacgcg cccaggtcaa tgcgcgctcc
    14761 atcagaacat ctgcgccgtt accaatccag gtaataacgc gttcttcacc tgcgacgggc
    14821 aactccagcg catacagcgc catatctacc gcagcagcaa gaccaggagc actgtcgacc
    14881 agcgtaccat caagatcaaa agcgacgccg cgaatatctt caaacttatt catgacttac
    14941 ctttgccagt tcactgcgca tttcatcaat gacttttttg tagtctggct ggtcgaagat
    15001 tgccgaaccg gcgacgaaca tatccgcgcc cgccgcagcg atttcgccaa tgttgttcac
    15061 cttcacgcca ccgtccactt ctagtcgaat gtcaaagcca gactcgtcga tacggcgacg
    15121 tacttcgcgc agtttatcca gtgtttgagg aatgaaagac tgaccgccga aaccagggtt
    15181 gacggacatc agcaggatca catccagctt atccatcacg taatccagat agctcagagg
    15241 tgtcgccggg ttaaatacca gacccgcttt acagccattt tctttaatca gttgcagcgt
    15301 gcggtcaaca tgctcggagg cttctggatg aaaggtaatg atgctggcac cagcggcagc
    15361 gaaatcaggc acaatgcgat cgacgggttt caccatcagg tgtacgtcga taggggcggt
    15421 aatgccatag ttacgcaagg atttcagcac cattggccca atcgtcagat tgggaacata
    15481 gtggttatcc atgacgtcaa aatgcacgac atcagcgcca gctgccaggg cttttgcggt
    15541 atcttcaccc aggcgggcaa aatcagccga cagaattgag ggggcaatca aatactgttt
    15601 catccgcttc tccttgagaa ttattttttc gcgggtgaaa cgactcctgg tttgtacaaa
    15661 gccagcagtt cgtccacctt tttacgtgtg ccgccgttgc tgcttatact gcgtcgaact
    15721 ttgacgacat gcaattttgc gcgctgatac cactcacgcg ttaacatcgt atcgtgattg
    15781 gagatcagca ctggaatatg gcgctcaacc agaccttcgg cgatctccgc cagatgcgct
    15841 tgttgttcaa gcgtaaaact gtttgtgtga tacgccgtaa agttggcggt cgcagacagc
    15901 ggtgcataag gcggatcgca atagacgacg gatgcatcat ctgcgcgcgc catgctatcg
    15961 gcgtaagact cacaatagaa aaaggcattc tgcgcttttt cagcgaagtg atacaactct
    16021 gcttccggga aatagggttt tttgtagcgg ccgaacggca cgttaaactc accgcgcaga
    16081 ttgtaacgac acaggccgtt gtaaccgtag cggttcaaat ataaaaacag taccgcccga
    16141 cggaacggat cctggctttt gttgaactct tcgcggaact gatagtaaac ctcggcgcaa
    16201 tttgtttcgg gaacaaacag ctcgcgtgcg gcctgtacgt actcatcagt acgcatcttc
    16261 acaatgttat agagactgat caggtcgcta ttgatatcgg caaggatata acgagaaaag
    16321 tcggtgttga gaaacaccga cccggcacct acaaaaggct caaccagaca ttcgcccttg
    16381 ggcaaatgcc gtttaatatc atcaagcagg ggatacttgc cccctgccca cttcaaaaaa
    16441 gcgcgatttt tcttcatgct gactaactaa ttacaccttc tccggctgtg gagaaagctc
    16501 cgacagcatc cagcgcttca ggcaactccc gcaacgataa accattgcgg gagataacct
    16561 tgattacttc agatcggcct gtacctgacg cagcggtttc gcccacgggt ttttggcctg
    16621 gacatctgct ggcaatgtag ataccgcttt tttcgcctct tctttcgaag cgtacacgcc
    16681 agaaaccagg acataccacg gctgaccatt acgcgtcgtt tcatagacaa cgtagttttt
    16741 cagattctct ttcttcgccc aaccgttcag gttgtcgtag ttagaggaac tgctcagctg
    16801 cagagtgtaa tggctggacg gtgccgattt caacgaacca acattacctg cggtcttcgc
    16861 cccagcagcg ggtgttgctg tggtttgcgc cggggatgcc gtctgtactg gagccgtagt
    16921 cgccgtctct tttggtgctg gcgtagaagt cgcagccggt gccttcgtgc tcgccacagg
    16981 ggcagctggt tcagtacgct tcggcgtctg tgctaccggc ttcggctccg ttttcacggt
    17041 tgcttgcggt tttttcggtt caatcaccgc ctgctgacga gctgggcgcg tagtggacgg
    17101 acgttcagcg gtttgcgttt tcgccgtgtc acgcgatgca ttgccattgc gaacaggcgc
    17161 aaccgttgcg ggttcagtcg gcaacgtgga attgaccgcc acattgttca gctgttgctg
    17221 attttgtggc tgggtcagcg cattgttcag gtcaccctgc acttcaacac gttgttgacc
    17281 atccgttgcc accggggttt gcccttgagt cggcgtagaa gagatcggtg gcagagaaac
    17341 atcctgctga gtattttccg cagacgtggt tcccggcgct ggctgcacgc cattcgcctg
    17401 atcggtcgca ttgccagcaa gatcaatact cttctcgcca gacgcggttt gatcgctgga
    17461 agtggtcgag ggggctttta gcgcagaacc gataccgatg atcaacagca gtagaaccag
    17521 aatgccgacg cccatcatca tatactgacg agaagcgggt ttactggctg cttttttgcg
    17581 cttacgcgga cgacgctcta cgcgctcttc atccacggtt tcatcttcgg attcgtcaat
    17641 ttcttcttcg atttccggtt cctcattgcg ctctttttgc gcacgggtcg gacggcgatc
    17701 gtcagtgtca tcaagttcaa tatcatcaaa attgatctgc ggttcgccac gttcagtacg
    17761 ctcagaacgt tcagaagatt gacgagaacg accagtacga cgatcgctgg gatcgggttt
    17821 cagctcgtct tctggtttga attcatccat ttaacacccc actaaaaggt taatgcttac
    17881 cacgttgcaa ttaacctgaa gctaatagac cgcttgataa gcggcctgac ctttcttgtt
    17941 gttacgctga ttgacaatcg gcaatggcgt taagaacaag ctcgtgcgaa acgccgctgc
    18001 gaacttcact cttaccaatt gccaacggaa gaattaagcg catctctccc gcaaggactt
    18061 tcttgtcacg cagcatatgc ggtaaatacg cctgcgcgga catttcgcgc ggcccattga
    18121 ccggtaaccc agcccgcttg agcagggtta taatacgctg cgtttcggca gaactaaact
    18181 gcccgagacg ttccgacgtc cgcgccgcca tcaccatacc cgcagcgacc gcttcaccat
    18241 gtaaccaatt gccatacccc atttcagctt caatggcatg accaaaggtg tgtcccagat
    18301 tcagtaaagc acgtaacccg gtttcgcgct cgtcggcggc gacaacttct gccttcagtt
    18361 cacaacaacg gcgaatacag tacgccattg ccggaccgtc cagacgcaac aacgcatcca
    18421 gattctcttc cagccagtta aaaaacgcac cgtcaagaat aatgccgtat ttgatgactt
    18481 ctgccagccc cgacgctaac tcacgcgggg gaagcgtttt cagacagtcg agatccacca
    18541 ccactgaagc aggttggtag aacgcgccaa tcatgttttt accgagggga tggttgaccg
    18601 cagttttgcc gccaacggag gaatcgacct gcgacagtaa cgtcgtcggg acttgaatga
    18661 aacggacacc gcgctgataa ctcgccgccg cgaagccggt cagatcgccc actacgccgc
    18721 cgccaagcgc caccagcgta gtatcgcgac catgcggttt ttgtaacaac gccgtaaaga
    18781 cggtatcgag tacagccaag cttttatact gctcgccgtc agggaggata acgctatcga
    18841 cgttaacacc cgcctgttca agtacgccgc ggaccttatc gagatacaga ggagccaggg
    18901 tttcgttggt gaccaacatg acctgctcgc ccgatttcag cggtaagaat gaagctggtt
    18961 cattaaacaa accagatgcg atggtaattg ggtaactacg ttccccgaga gtaacgacaa
    19021 tcctctccat aacgcgacat ccaccttaat tactgtaccc gcagacgagt gtatataaag
    19081 ccagaattag ttgctttcca gcatgtgaat aatctggttt gcaaccactt tagcgctttg
    19141 atcatcagta cgaatggtca cgtcggcaat ctcttcatac agcggattgc gttcattggc
    19201 caacgcttcc agaacttcac gcggcggtgt ttcaacgtgc agcaacgggc gttttttatc
    19261 acgctgcgtg cgtgcaagtt gcttttcgat ggtcgtttca agataaacga caacgccacg
    19321 agcggaaaga cggttacgcg tttcacggga tttcacagag ccgccgccag tagccagcac
    19381 aataccctgt ttctcggtca actcattgat gaccttttct tcgcgatcgc ggaagccttc
    19441 ttcgccttct aaatcgaaaa cccagcccac atcagctccg gttcgtttct caatctcttg
    19501 atcggaatcg taaaattcca tattgagttg ttgagctaac tggcgcccaa tagtgctttt
    19561 tccggcaccc ataggcccaa ccagaaagat attgcgtttc tctgccattt tttcggtact
    19621 actaagacta ttcgttaatg ataaacccgc ttcgctcaga gagcgccgca ggacatgaac
    19681 tgaaacctca taagatattg cgagagtcag actgaaaatt atctcaatac tccagcgggt
    19741 ttggcaactg aataaatcac ccatccctct gcatatctgg tcgctgcaag cgcgctgcct
    19801 tgctaccacc gctctggcga taaatcaccg ggtaagatta gcgtaaaaaa gacagcaaaa
    19861 tgccgcctga atgataaatc atcatcatgg aacgcaggca gcgaagagca ccaactctca
    19921 aatcggtact ccttgtatgc taaatacctg cgcgcgtcaa atagatgaaa cacgttcagc
    19981 gtaaaaacat taccgctttt acggctgttt actcactgga aaccagtcgt ggcgtgataa
    20041 acaccactaa ctcgcgtcgt tcatcttctt ttccgtcatg acgaaataat tgcccgaacc
    20101 agggaatgtc gccaagcaac ggtacgctat cctgacccga tttattttta cgggtaaaaa
    20161 tgccgcccag cgccaacgtt tctccgcttt tgacctcgac ctgcgtttcg atctcctgct
    20221 tatcaatcgc cagcacttcg ccatcggcct gctgtagcac ctgccccgga acgttctggc
    20281 tgatgtgtaa tttcagccgg atgcgacctt tttgtaacac cgtgggcgtg acctccatcc
    20341 ccaggacggc ctctttaaat tccaccgacg tcgcgccact ttccccgctg gaaacctgat
    20401 atggaatttc gctcccctgt ttaatgctgg caggctgaag atgtgaggcc agcagacgcg
    20461 gactggcgat aatatccagc tgctgttttt gttcgagcgc ggaaagctca agatccagca
    20521 agcgtccgtt gatgcgccca atgttaaaac cgacatgcgt tgtcgccgtc gctacggaga
    20581 ggtcgctacc aagcgtggtg acttgcccaa cgccaccagc gtgttgcgca tcggccagcg
    20641 tccatttcac gcctaactca cgcaaacttt tttcattaat ggtgacaata tgcgccgaca
    20701 gctcaacctg cccgaccggc agatccattt gcgctaccca ctgttcaagc gcgcttaacg
    20761 ccgttttgtt atctcgtagc aaaaggcgat tggtgcgttt atcgacggtc atactccctt
    20821 tggcactcag tagcttctcc cccgctttcg ccagttctcc cgcgtcggcg tattgcaggg
    20881 ttatactgcg attttccagc ggcagatttg cctgcgcccg cgcctgctcc gcctcctggc
    20941 gggcgatatt gttattctgc caggcaatgg aatgcactga gagaatgttg ccttcctgcc
    21001 gcgttatcag tccggcgctt ttcactacag tttgtagtgc ctgcttccag ggaacatctg
    21061 ttagatgtaa cgacaccgta ccgctgacgt ctggcgacac gaccaggttc aacttctcct
    21121 gttcagccag cgcctgcaac acctgagcta ccggaacgtc atccaccatc agcgtcactt
    21181 tttgcggctt tgccgcctgt acgccgggta tcagcatcaa cagtagtgcg gctatccatt
    21241 gcttcatttg tatctccttg ccgttgccac aaccattgtg gcggttcgca gtttgtcccg
    21301 gtacccagcg ttagtacgtc tggcgtcagc tgtaaaattg tccagccgtt ttccagcaca
    21361 tcgttttgct gcacccgtcg ccatttcttt tgcccgtctt ttattacacc gatgatgcgc
    21421 tcgcctcgcc ctaccatccc ctgatagcgc cactggctaa gttcgctaat ccggcataga
    21481 tcttccggcg gtttaaaagg gtcacgcata ccggttaaaa ggcacaatgc aatacctgcc
    21541 aacaaccagc gtttaaccct catgcggcgt ctccagttgt agcgtgaaca aaagatcatc
    21601 accttccacg cttaacgaaa aacggctcac gctgacgttg cgctctgcca gccgtgtaaa
    21661 tgccgacggc actgcttccc acagcgtttt caacgccaac tcgcctccct gcgcggatgg
    21721 atgccaggaa accagttgcg cgccggataa ctgaaaatcc agtggcgaaa agggcagcgt
    21781 tttttcctcg ctgaagggag tggtgtctac caggcgatac agtgcggccc actgctggtg
    21841 atgacttgcc cgtagtcgaa ttaatgcgtc gcgctcttca tggtgtgtcg atgacagaaa
    21901 aatgagcgta actaacatca gcaaccagaa tgcccagcaa agctggcgga ggcggggtga
    21961 tgtggcgaac caccagtcaa agaacatgtt catcgctaac cttccttgtt aactgatact
    22021 caaattgcca gcgtccctgc gcatcctgct gcgtggctcc ccgctgattg agatgaaaag
    22081 atgcatcctg gcggagtgac gtttctagtg cgtttaacgc ggtaatgctt gttgtcagcc
    22141 ccttgatctc cagcgttccc tgctgccagc ttatcgttgt cagccaggcg tgctcgggta
    22201 aaagcgccgc cagtgcttcc agcgcagatt gccagtcgcg ggtaaattgt cgctggcgct
    22261 gccgttgcga acgctgttcg cgtaactgct gttgctccag caaacgtggc ttcgttatct
    22321 gtaagctgcg ggcgagttgt tgttccgcct gaagcaaaac tgcgtctatg cgcgcttcgg
    22381 cgctgcctgt cagacgcagt attagcgtta tcccgacggc cagcagcaga ggcgcaacga
    22441 acatcagcaa ccagaaacgc agaaaagcgg tccggcgttg ctgtcgccag ggcaaaaaat
    22501 taattggcgg gttcatcagt acgccttccc aagcgccagc cccagcgcga tggcaaagtc
    22561 tccacctggc ggcggtagcg gcggctgacg aacagaaacg gcctcccagg gatcaaatcc
    22621 gccttcgcca catatcgcga cgctttcggg atcaacggat aacgctgccg ccagctcctt
    22681 cgcgctagtc atccccaccg ccagtttgcg cccccagcta tagcgcgtcg cccacagcca
    22741 ctgttcgtta tcacgccagg ccagacattg ctgatgagaa ggtaaaaaag gcaggaatcg
    22801 ctgtaatgca ctggcatccg gggtgatcgc gctcacatga acacgcaacc tttctgccag
    22861 agtaagcagc gttgccagct ctttgctttg cgcggcagtc acgttatagg cgggactgag
    22921 tgagtcttcg ctgtaatcga agcgcaggga gtccggatcc atatccagct cgcgggccat
    22981 cgtccctgac agccaggccg tttgctcccg ctcaccaagg gacatcgacg ggcgcggaaa
    23041 tgaccgctgt aatgtgcgac tggcgggaaa cgccaacata atgtgatgac gctgcggcag
    23101 ttcgcgactc cacggtaaca acgttttagc cagctgctgc gcatcaacaa tccgcccatc
    23161 tttgataatg tcgttctcca gcggcaaccg ccaccagcgt tgcaaaaagc attcttttgc
    23221 gccccgcacg atcgcaaccg ctaccgcttc ttgctgttgt aaatgcaaac caatttgcca
    23281 gatcttaaat gccattgtga tgatctcctt atcacccgtc actctgacgg gtatatcaat
    23341 gcgtctggct tgcctttata ctaccgcgcg tttgtttata aactgcccaa atgaaactaa
    23401 atgggaaatt tccagtgaag ttcgtaaagt attttttgat ccttgcagtc tgttgcattc
    23461 tgctgggagc aggctcgatt tatggcctat accgctacat cgagccacaa ctgccggatg
    23521 tggcgacatt aaaagatgtt cgcctgcaaa ttccgatgca gatttacagc gccgatggcg
    23581 agctgattgc tcaatacggt gagaaacgtc gtattccggt tacgttggat caaatcccac
    23641 cggagatggt gaaagccttt atcgcgacag aagacagccg cttctacgag catcacggcg
    23701 ttgacccggt ggggatcttc cgtgcagcaa gcgtggcgct gttctccggt cacgcgtcac
    23761 aaggggcaag taccattacc cagcagctgg cgagaaactt cttcctcagt ccagaacgca
    23821 cgctgatgcg taagattaag gaagtcttcc tcgcgattcg cattgaacag ctgctgacga
    23881 aagacgagat cctcgagctt tatctgaaca agatttacct tggttaccgc gcctatggtg
    23941 tcggtgctgc ggcacaagtc tatttcggaa aaacggtcga ccaactgacg ctgaacgaaa
    24001 tggcggtgat agccgggctg ccgaaagcgc cttccacctt caacccgctc tactcgatgg
    24061 atcgtgccgt cgcgcggcgt aacgtcgtgc tgtcgcggat gctggatgaa gggtatatca
    24121 cccaacaaca gttcgatcag acacgcactg aggcgattaa cgctaactat cacgcgccgg
    24181 agattgcttt ctctgcgccg tacctgagcg aaatggtgcg ccaggagatg tataaccgtt
    24241 atggcgaaag tgcctatgaa gacggttatc gcatttacac caccatcacc cgcaaagtgc
    24301 agcaggccgc gcagcaggcg gtacgtaata acgtgctgga ctacgacatg cgccacggct
    24361 atcgcggccc ggcaaatgtg ctgtggaaag tgggcgagtc ggcgtgggat aacaacaaga
    24421 ttaccgatac gctgaaggcg ctgccaacct atggtccgct gctgcctgcc gcagtcacca
    24481 gcgccaatcc tcagcaagcg acggcgatgc tggcggacgg gtcgaccgtc gcattgagta
    24541 tggaaggcgt tcgctgggcg cgtccttacc gttcggatac tcagcaagga ccgacgccgc
    24601 gtaaagtgac cgatgttctg caaacgggtc agcaaatctg ggttcgtcag gttggcgatg
    24661 catggtggct ggcacaagtg ccggaagtga actcggcgct ggtgtcgatc aatccgcaaa
    24721 acggtgccgt tatggcgctg gtcggtggct ttgatttcaa tcagagcaag tttaaccgcg
    24781 ccacccaggc actgcgtcag gtgggttcca acatcaaacc gttcctctac accgcggcga
    24841 tggataaagg tctgacgctg gcaagtatgt tgaacgatgt gccaatttct cgctgggatg
    24901 caagtgccgg ttctgactgg cagccgaaga actcaccacc gcagtatgct ggtccaattc
    24961 gcttacgtca ggggctgggt cagtcgaaaa acgtggtgat ggtacgcgca atgcgggcga
    25021 tgggcgtcga ctacgctgca gaatatctgc aacgcttcgg cttcccggca caaaacattg
    25081 tccacaccga atcgctggcg ctgggttcag cgtccttcac cccaatgcag gtggcgcgcg
    25141 gctacgcggt catggcgaac ggcggcttcc tggtggaccc gtggtttatc agcaaaattg
    25201 aaaacgatca gggcggcgtg attttcgaag cgaaaccgaa agtagcctgc ccggaatgcg
    25261 atattccggt gatttacggt gatacgcaga aatcgaacgt gctggaaaat aacgatgttg
    25321 aagatgtcgc tatctcccgc gagcagcaga atgtttctgt accaatgccg cagctggagc
    25381 aggcaaatca ggcgttagtg gcgaagactg gcgcgcagga gtacgcaccg cacgtcatca
    25441 acactccgct ggcattcctg attaagagtg ctttgaacac caatatcttt ggtgagccag
    25501 gctggcaggg tactggctgg cgtgcaggtc gtgatttgca gcgtcgcgat atcggcggga
    25561 aaaccgggac cactaacagt tcgaaagatg cgtggttctc gggttacggt ccgggcgttg
    25621 tgacctcggt ctggattggc tttgatgatc accgtcgtaa tctcggtcat acaacggctt
    25681 ccggagcgat taaagatcag atctcaggtt acgaaggcgg tgccaagagt gcccagcctg
    25741 catgggacgc ttatatgaaa gccgttcttg aaggtgtgcc ggagcagccg ctgacgccgc
    25801 caccgggtat tgtgacggtg aatatcgatc gcagcaccgg gcagttagct aatggtggca
    25861 acagccgcga agagtatttc atcgaaggta cgcagccgac acaacaggca gtgcacgagg
    25921 tgggaacgac cattatcgat aatggcgagg cacaggaatt gttctgatta aaaaggcgct
    25981 tcggcgcctt ttcagtttgc tgacaaagtg cacttgttta tgccggatac ggcgtgaacg
    26041 cgttatccgg ctaacaaaat cgtgaaaact caataaattg cagaaacccc ataagcctga
    26101 taaacattgt gcatcaggca aacttcacgc atttacactc gcccctgccc tttcaaccat
    26161 tcgcgcacga ggaacagcgc actgacattg cgcgcttcat tgaagtcagg gtcttccagc
    26221 aaatccatca tatgcgccag cggccagcgc acctgtggta gcggctctgg ctcatcgcct
    26281 tccagtgatt ccgggtagag atcttgcgct accacgatat tcattttgct ggaaaagtaa
    26341 gacggtgcca tgctgagctt cttcaaaaaa gtcagatcgt tcgctccaaa tccaacctct
    26401 tcttttagct cgcggttagc ggcttcgtag acgctttcac ccggatcaat taatcctttc
    26461 gaaaaaccta attcgtagga ttcagttccc actgcgtatt cgcggatcag gatcaggtga
    26521 tcgtccacaa tcggcacaat catcactgct tcccggttgg ttggacgcat tcgttcataa
    26581 acacgccgca cgccattgct gaactccaga tccacgctct cgacggtaaa cagtcgggaa
    26641 cgggctacag tttcaacatt cagaatggtg ggtttttgta atgatttgct catcgtggga
    26701 tctatgctgt gaaatcagcg gttattgtgc gatatcggac acgctttcgg caatgtgaat
    26761 tgcatgttat ttacatttat gtaacttaat aaataatcgt cctcaaatca aattaaaagt
    26821 caataggttg aaataactcc aggaatttgc tgatattccg ccttcagagg gtttgctatg
    26881 atcagcggtt actgtgatgt gcttaatgat gctcaagtta aactccacgc ttgccgatag
    26941 ccaaccgcag aatcatgtat tgtgtccggt gcgactgacc acgcctgaca gactaagtaa
    27001 gatggggaaa gcatgagcac cattgtgatt tttttagctg ctttgctggc ctgctcacta
    27061 cttgcgggat ggctgataaa agtgcgatcc agacggcgtc agctgccctg gaccaacgcc
    27121 ttcgcggatg cgcaaacgcg taaactcaca cctgaagaac gtagcgccgt tgaaaattat
    27181 cttgagagcc tgacgcaggt attacaggtg cctggcccaa cgggagccag cgcggcaccg
    27241 atctctctgg cgctgaatgc cgaaagcaac aacgtcatga tgctgacaca cgctatcacg
    27301 cgttacggca tctctaccga cgatccgaat aaatggcgtt actacctcga ttcggtagaa
    27361 gtccacctgc cccctttctg ggaacagtac atcaacgatg agaataccgt tgaactgatt
    27421 cataccgatt cgctgccgct ggttatttca ctcaacggtc atacgctgca ggagtacatg
    27481 caggaaactc gcagctatgc cttgcaacct gttccgtcaa cgcaggcgtc gattcgcggg
    27541 gaagagagtg agcaaatcga gctactcaat attcgcaaag aaacgcatga agaatatgcg
    27601 ctgagtcgtc cgcgcgggct gcgtgaagcg ttgctgatcg tcgcctcctt cctgatgttc
    27661 tttttctgcc tgattacccc ggatgtattt gttccgtggc tggcaggcgg cgcgttactg
    27721 ctgctgggcg caggtctgtg ggggctattc gcgcccccgg caaaatcctc cctgcgggaa
    27781 attcattgtc tgcgcggtac accccgtcgt tggggattgt ttggcgaaaa cgatcaggaa
    27841 cagatcaaca atatttcact cggtattatc gacctggtct atcccgcaca ctggcagcca
    27901 tacattgctc aggatctcgg tcaacaaacc gatatcgata tctatctcga ccgccatgta
    27961 gtgcgtcagg gacgatatct ttcgctgcat gatgaagtaa aaaactttcc gttacagcac
    28021 tggctgcgca gtacgattat cgctgcgggc tcgctgctgg tgctgtttat gctgttattc
    28081 tggatcccgc tggatatgcc gctgaaattc actctctcat ggatgaaagg cgcgcagacc
    28141 attgaagcca ccagcgtaaa acaactggct gacgctggcg tgcgggtagg cgatacattg
    28201 cgtattagcg gtacgggaat gtgtaatatt cgaacttccg gaacctggag cgcgaaaacc
    28261 aattcacctt ttttaccgtt tgactgctcg cagatcatct ggaacgacgc ccgctcattg
    28321 ccattaccag aatctgaact ggtcaacaaa gcgacggcat tgactgaagc agttaatcgc
    28381 cagctgcacc ctaaaccgga agatgaatct cgcgtcagtg cctcattacg ttcagcaatt
    28441 caaaaatccg gcatggtatt gcttgatgat tttggcgaca ttgtactgaa gacagcggat
    28501 ttatgttctg ccaaagatga ctgtgtgcga ctgaaaaatg cgctggtcaa tctcggcaac
    28561 agtaaagact gggacgcgct ggtaaaacgc gccaacgccg ggaagctcga tggcgtgaat
    28621 gtgttattac gcccggtgag tgcggaatcg ctggataacc tggtggcaac ctccaccgcg
    28681 ccgtttatca cgcatgaaac ggcgcgagcg gcacaatcac taaacagtcc ggcccccggc
    28741 ggattcctga ttgtcagcga cgaaggcagc gattttgttg atcagccctg gccttcggca
    28801 tcactttacg actacccgcc gcaagaacag tggaacgctt tccagaaact ggcacaaatg
    28861 ctgatgcata cgccgtttaa cgccgagggt atcgtcacaa aaatcttcac tgacgccaat
    28921 ggtacgcagc atattggcct tcatccgatc ccggatcgtt ccggcctgtg gcgctatctc
    28981 agcaccacat tgctgctact gacgatgctg ggtagcgcca tttacaatgg cgtacaggcc
    29041 tggcgtcgtt accagcgtca tcgcactcgc atgatggaga ttcaggccta ttatgaaagc
    29101 tgcctgaacc cgcaactgat caccccttca gaaagcctta tcgaataaca cgtttgcgcg
    29161 gcaggttatg ctaccctgtc gcgcaaattg cttcactctg gagatttccc tcatgcatat
    29221 caacattgcc tggcaggacg tagataccgt tctgctggat atggacggca cgttgctcga
    29281 cctcgccttc gataactatt tctggcaaaa gctggtgcct gaaacatggg gcgcgaaaaa
    29341 cggggttacg ccacaggaag cgatggaata tatgcgccag caatatcacg acgtacagca
    29401 tacgctaaac tggtactgtc ttgattactg gagtgagcaa ctgggtctgg atatctgtgc
    29461 gatgaccacc gagatgggac cgcgtgccgt actgcgtgaa gataccattc cgtttcttga
    29521 ggcactgaaa gccagcggta agcagcgaat tttgctcacc aatgcgcatc cgcacaacct
    29581 ggcggtaaaa cttgagcata ccggtctgga cgcacacctt gatttattac tttccaccca
    29641 cacatttggt tatccgaaag aggatcagcg gttatggcat gcggtggccg aagctacggg
    29701 tctgaaagct gaaagaacgc tgtttattga tgacagcgaa gcgattctcg atgctgccgc
    29761 gcaatttggt attcgttact gcctcggcgt gactaatcct gattccggga ttgccgagaa
    29821 acagtatcaa cgccatccgt cactgaatga ctaccgccgc ctgatcccct cgctaatgtg
    29881 aaggagacgc catgaaagag aaacctgctg ttgaggttcg actggataaa tggctatggg
    29941 ctgcccgttt ttataaaacc cgcgcgctgg cccgtgaaat gattgaaggc ggtaaggtgc
    30001 attacaacgg gcagcgcagc aagccgagca aaatcgtcga gctgaatgcc acgctcactc
    30061 tgcgccaggg aaatgacgaa cgcacggtga ttgtaaaggc gattactgaa cagcgtcgcc
    30121 ccgccagcga ggcagccttg ctgtatgaag agactgcgga aagtgtagag aaacgcgaaa
    30181 aaatggcgct ggcacgtaaa cttaatgcct taaccatgcc gcacccggac cgacgcccgg
    30241 acaaaaaaga gcgccgcgac ctgttacgat ttaaacacgg cgacagtgaa taactgtcac
    30301 ctgcaagaga gatgattatg ccgcaacatg accaattaca tcgctatctg tttgaaaact
    30361 ttgccgtgcg cggcgaactg gtaaccgttt cggaaaccct gcaacagatc cttgagaacc
    30421 acgattatcc gcagcccgtt aaaaacgtgc tggcagaact gctggttgcg accagcctgt
    30481 taaccgctac gctgaagttt gatggtgata tcaccgtaca gctgcagggc gacggtccga
    30541 tgaatctggc ggttattaac ggtaacaata accagcagat gcgcggtgtg gcgcgcgtgc
    30601 agggcgaaat tccagaaaat gccgacctga aaacgctggt cggcaatggt tacgtggtga
    30661 tcaccattac cccgagcgaa ggcgaacgct atcagggcgt agttggtctg gaaggtgata
    30721 ccctggcggc ctgcctggaa gattacttta tgcgttctga acagctgccg acgcgcctgt
    30781 ttattcgcac cggcgacgta gacggcaaac cggctgcagg cggtatgttg ttgcaggtaa
    30841 tgcctgcgca aaatgcccag caggacgact ttgaccacct ggcgacgcta accgaaacca
    30901 tcaaaaccga agaactgctg accttaccgg caaacgaagt gttgtggcgt ttgtatcacg
    30961 aagaagaggt gacggtttac gatccgcagg atgtggagtt caaatgcacc tgctcgcgtg
    31021 aacgttgcgc cgatgcgctg aaaacgctgc ctgatgaaga agttgatagc atcctggcgg
    31081 aagatggcga aattgacatg cattgtgatt actgcggtaa ccactatctg ttcaatgcga
    31141 tggatattgc tgaaatccgc aacaacgcgt ctccggcaga tccgcaagtt cattaatgag
    31201 tatgtccggc agagagggct ctgccggatt ttacgactaa tacacctgat gcgctttgtc
    31261 actcattcag attcacattc agcctttcac catccactac aagatcgcgc cacgctttag
    31321 gcttcgtccc cagttttcca tccttcgcag ctgtgagtaa tttttctttc gttatttcgt
    31381 tcggaagtaa actcatatca agcgcgtccc attcttttct gtctgagtca aagccataga
    31441 caatgactct gtcatcatta aaagcaaaca ggatccgctc cgcctgacca tcactattca
    31501 gatcttgctc gaccaggacg caggcgtctt tttcaataca ggtcatcacg ttatagcgat
    31561 cctggattaa ggccgaccag aatgtcgcat caggtttaac agaaccaggg gcaattaaca
    31621 cattatcggc taatactttt tccgatacct gttgctgaag atgttgctct ccatctaacg
    31681 ccatcagcag atcccgcgcg cgtttcgggt ctttcataaa cccggcatcg cttttcagcg
    31741 actcaagcgc agcacgtcca tagcgaccgc tctgctcgag catgtagata gttacctggt
    31801 ctgacgtgtt tttgccgctc tgataacgcg ccatatggct gttcacgcta atgcgcatac
    31861 tgtccagcac cggcgaatta agaagcacca gtatcaccaa caccaataac caaaccgcaa
    31921 ggttcacttt gccctgaaga acaacgggat tttgcccttt acgccagacg atgctgacaa
    31981 aataccccag cgaccacacc agtaacacca gcaccgccag cacgccctgc aagcggtcga
    32041 cagtccagcc gtactgagcg acccgcagcc ataacgccca ggcggcgacg aacacataca
    32101 gcggagcaac cagcaaagcg gttttaatca ggcaacgcaa cggccctgtc cagggaagtg
    32161 acgctttttg cggatcgcgg acaatagcca ttaagatcaa ttgcaaaaag gccagcgtca
    32221 acagcaaccc ggcggcggag atgtggcgag aaatcgcgct caggcccgta aacggcaggg
    32281 tgatgataaa catcagggtt agcaatgata ctaacggcag caaccccgtg gcgattaacg
    32341 tgaacaactt ttgaatagag tcgattaaac gtgactgtgt tcgcgcgagg atcaccgcca
    32401 gcgcggtaac cagacctaac gtgagataaa taaaccagtc ggttgcaaaa aagagcgtat
    32461 tgaaaaacgt gatgccaaca agtttaaaca actcactcca cagtaaaagc accagccacg
    32521 tcaagccatt ggcgagaaaa atcaccagta atataagtac gttatgccat actgactggt
    32581 aaaaatagcg atagcggcta ctgtcattgc ggatgcgaag gctttgttgt atccacggta
    32641 gcaacaacat tgccatcaac agcagatagc aaccaaaatc ccaaagcgcc ttttcagctc
    32701 tccaggggtt catgccatca gtttgccact tcagccagcc gctcatcccc agcgtggcaa
    32761 taaacactag cgccagccat ccccaaaggc gcttctgttt aaaagagatc acggagaaga
    32821 gtaaaacgga tgaaaacgcg acggtcgcag gcacgccata aacaatccaa ctgtgatttt
    32881 ttccggaaag ccaggcgatc agcaggtagc aaaccagacc ctgaagtaat ccggtagcaa
    32941 tcatccccca gcgtgttgcg ggtgaaagtt caacgttatc catgttggtt atccagaatc
    33001 aaaaggtggg ttaattatcg catccgggca gtagtatttt gcttttttca gaaaataatc
    33061 aaaaaaagtt agcgtggtga atcgatactt taccggttga atttgcatca atttcattca
    33121 ggaatgcgat tccactcaca atattcccgc catataaacc aagatttaac cttttgagaa
    33181 cattttccac acctaaaatg ctatttctgc gataatagca accgtttcgt gacaggaatc
    33241 acggagtttt ttgtcaaata tgaatttctc cagatacgta aatctatgag ccttgtcgcg
    33301 gttaacaccc ccaaaaagac tttactattc aggcaataca tattggctaa ggagcagtga
    33361 aatgcgcgtt aacaatggtt tgaccccgca agaactcgag gcttatggta tcagtgacgt
    33421 acatgatatc gtttacaacc caagctacga cctgctgtat caggaagagc tcgatccgag
    33481 cctgacaggt tatgagcgcg gggtgttaac taatctgggt gccgttgccg tcgataccgg
    33541 gatcttcacc ggtcgttcac caaaagataa gtatatcgtc cgtgacgata ccactcgcga
    33601 tactttctgg tgggcagaca aaggcaaagg taagaacgac aacaaacctc tctctccgga
    33661 aacctggcag catctgaaag gcctggtgac caggcagctt tccggcaaac gtctgttcgt
    33721 tgtcgacgct ttctgtggtg cgaacccgga tactcgtctt tccgtccgtt tcatcaccga
    33781 agtggcctgg caggcgcatt ttgtcaaaaa catgtttatt cgcccgagcg atgaagaact
    33841 ggcaggtttc aaaccagact ttatcgttat gaacggcgcg aagtgcacta acccgcagtg
    33901 gaaagaacag ggtctcaact ccgaaaactt cgtggcgttt aacctgaccg agcgcatgca
    33961 gctgattggc ggcacctggt acggcggcga aatgaagaaa gggatgttct cgatgatgaa
    34021 ctacctgctg ccgctgaaag gtatcgcttc tatgcactgc tccgccaacg ttggtgagaa
    34081 aggcgatgtt gcggtgttct tcggcctttc cggcaccggt aaaaccaccc tttccaccga
    34141 cccgaaacgt cgcctgattg gcgatgacga acacggctgg gacgatgacg gcgtgtttaa
    34201 cttcgaaggc ggctgctacg caaaaactat caagctgtcg aaagaagcgg aacctgaaat
    34261 ctacaacgct atccgtcgtg atgcgttgct ggaaaacgtc accgtgcgtg aagatggcac
    34321 tatcgacttt gatgatggtt caaaaaccga gaacacccgc gtttcttatc cgatctatca
    34381 catcgataac attgttaagc cggtttccaa agcgggccac gcgactaagg ttatcttcct
    34441 gactgctgat gctttcggcg tgttgccgcc ggtttctcgc ctgactgccg atcaaaccca
    34501 gtatcacttc ctctctggct tcaccgccaa actggccggt actgagcgtg gcatcaccga
    34561 accgacgcca accttctccg cttgcttcgg cgcggcattc ctgtcgctgc acccgactca
    34621 gtacgcagaa gtgctggtga aacgtatgca ggcggcgggc gcgcaggctt atctggttaa
    34681 cactggctgg aacggcactg gcaaacgtat ctcgattaaa gatacccgcg ccattatcga
    34741 cgccatcctc aacggttcgc tggataatgc agaaaccttc actctgccga tgtttaacct
    34801 ggcgatccca accgaactgc cgggcgtaga cacgaagatt ctcgatccgc gtaacaccta
    34861 cgcttctccg gaacagtggc aggaaaaagc cgaaaccctg gcgaaactgt ttatcgacaa
    34921 cttcgataaa tacaccgaca cccctgcggg tgccgcgctg gtagcggctg gtccgaaact
    34981 gtaatgattt gaagctggag aatatctatc cagtatctta tagaaagcaa aacgggaggc
    35041 accttcgcct cccgtttatt tacccttctt ttgtcgtgcc ctgcgcccgc gttaccggca
    35101 ctggcagcca ggcgcgaatg gaaagcccgc cccgctcgct ggtgccaagc tccagcatcc
    35161 cgttatggtt atccacgata cgctgcacaa ttgccagccc taatcccgtg ccgctaatgg
    35221 tgcgcgcact gtcgccgcgg acaaacggct ggaacaggtg cttacgttgt tccggcgcaa
    35281 ttcccggacc gtcatcttcc acctggaacc aggcgcgatt cggctccgtt ccgctgctga
    35341 ctttgatcca gccattgcca taacgggcgg cgttgaccac catattcgcc accgcgcgtt
    35401 tgatcgacag cgggtgcatt ttcacttcaa tgctgccggg gtaaagcgcg gtttcaattt
    35461 cccgctcata gccactttcg gcagcaatca cctcaccgag tactgcatta agatccgcca
    35521 tttccatcgg catctcctgc ccggtgcgca ggtagtcgat aaactgctca atgatggcgt
    35581 tgcactcttc gatatcttta ttgatcgatt ctgccagata gccatcctgc tcgctcatca
    35641 tctcagtcgc caggcgaata cgcgtcagcg gcgtgcgcaa gtcgtgactt acccccgcca
    35701 tcagcagcgt gcggtcatcc gccagttgct taacaccagc cgccatatgg ttaaaggcac
    35761 gggtaacgga acgcacctcc gaagcgccat actcacgcag cggcggcgga ataatccctt
    35821 taccaacctg caaggctgcg tgttcgagat cgaccaacgg tcggttctgg atacgaataa
    35881 acagccacgc cccgcctatc gccaatagca taatcgccag cgtatagcgg aacagcggag
    35941 agaaatcgcc ctgatgaatt tcggtcagcg gcacgcgtac ccagatattg ggcgacagcc
    36001 aggttttcag ccagacgaca ggcgaacttt tgttgacctc aacgcgcact tccgtcgggc
    36061 cgcccagttg ctgcgccatc tgatggctta agaattcata gtgttgcgcc caacgcagac
    36121 ctgcctcttc ggcagcctcg ttggagtaga gagagatccc cagctcacgg tagatctccc
    36181 gacggaaagc gggaggcaca accaactgcg tgccgtcctc cagttgcagt ttgtcggtca
    36241 tcaacatacg cacttcgtac gcgaggactt tattaaactg ctggaggctc ggcaaaatcg
    36301 cgaagttcag caccaccaga taagtcgtca ccaggctggc gaacagcaag gtgacgatga
    36361 gcaataacgt acgggcaaat gaacttcgtg gcgagaagcg caatcgcctc atgctttaga
    36421 gccgtccggt acaaagacgt agcccagacc ccagacggtc tgaatgtaac gcggatgcgc
    36481 tggatcttct tccaccatgc ggcgcagacg cgaaatctgc acgtcgatgg agcgttccat
    36541 tgcggaatat tcacgaccac gggcaaggtt catcagctta tcgcgggaga gcggctcacg
    36601 cggatggctg accagtgcct tcagtaccgc aaactcaccg ctggtgagcg gcatcggctc
    36661 gtcttcgcgg aacatttcgc gcgtaccgag gttaagtttg aacttaccga aagcaattac
    36721 cgcctcttcc tgtgacggtg cgcctggcag ttcgttcgcc tgacgacgca gcaccgcacg
    36781 gatacgggcc agcagttcac gcgggttaaa cggttttgga atgtagtcgt cagcgccaat
    36841 ctccaggcct acgatacggt ccacttcttc ccctttcgcc gtcaccataa tgatcggcat
    36901 cgggttgctc tgactacgaa gacgtcggca aatcgacaag ccatcttcac caggtaacat
    36961 taaatccagt accataagat ggaaagattc acgagtcagc aggcgatcca tctgttctgc
    37021 attagcgacg cttcgaacct ggaagccttg ttcggtgaga taacgttcca gcagcgcacg
    37081 caggcgcatg tcgtcatcga ccaccagaat cttgtagttc tcttgcattg tttgtactcc
    37141 caaaggttcg caacaatttg taagcgtgta ttcttaaaaa agctcacgtt cgtcaccagc
    37201 taaatctggt atgaatttca gcctaaattg ttacaaagca tattaaacag cagcttaagt
    37261 atacaattta ttcggcgaaa cattattgat tctgttgata tgatcacgtt atacccaatg
    37321 tgcgcattat caaacagaca aagggaatca acgagatgaa aacgcccctg gttacccggg
    37381 aagggtatga aaaactcaaa caagagctta attatctctg gcgtgaagaa cgcccggagg
    37441 tcacaaaaaa ggtgacctgg gccgcaagtc tgggcgaccg cagcgaaaat gctgactatc
    37501 agtataataa aaagcgtctg cgtgaaatcg accgtcgcgt gcgctatctc actaaatgcc
    37561 tggaaaatct caaaatcgtc gattactccc ctcagcagga aggcaaagtc ttttttggcg
    37621 cgtgggtgga gattgaaaac gacgatggcg tgactcaccg tttccgtatt gtcggctacg
    37681 atgaaatttt tggccgtaaa gattacatct ctatcgattc cccgatggcc cgcgcattgc
    37741 tgaaaaaaga agtcggcgat ctggcggtgg tgaatacccc tgccggggaa gcgagctggt
    37801 atgttaatgc tatcgagtac gtgaaaccgt aaggaagagt cttaacctcc tgccgatggc
    37861 tggcattttt gccagccagt ccgtataact atcccctgat ttttgatccg aaaagatgaa
    37921 ctcaaaccat gatgaatgat tcgttctgcc gcattattgc gggtgaaatt caggcgcgcc
    37981 cggaacaggt tgacgctgcc gttcgcctgc ttgacgaagg gaataccgtg ccgtttatcg
    38041 cacgttatcg taaggaaatc accggcggtc tggatgacac gcagctgcgt aatctggaaa
    38101 cgcgtctgag ctatctgcgc gagctggaag agagacgtca ggcgatcctc aagtccattt
    38161 ccgagcaagg caaactcacc gatgatctgg cgaaggccat caactccacc ctaagcaaaa
    38221 ccgaactcga agacctctac ctgccctaca aacctaaacg ccgcacccgc gggcaaatcg
    38281 ccattgaagc agggcttgag ccgttggctg acctgctgtg gagcgatccg tcacacacgc
    38341 cagaagtcgc cgctgcacaa tatgttgatg ccgataaagg cgtggcagat accaaagccg
    38401 cgctggatgg cgcgcgctat atcctgatgg aacggtttgc cgaagatgcc gcgctgctgg
    38461 cgaaagtgcg tgattatctg tggaagaacg cgcatttggt ttctacggtg gtgagcggta
    38521 aagaagagga aggggcgaaa ttccgcgact atttcgatca tcacgaaccg ttgtccacgg
    38581 tgccttctca ccgcgcgctg gcgatgttcc gtgggcgtaa cgaaggcgta cttcagcttt
    38641 cgctgaatgc cgatccacag ttcgatgagc cgcccaaaga gagctattgc gagcaaatca
    38701 tcatggatca ccttggcctg cgcctgaaca atgccccggc ggatagctgg cgcaaaggcg
    38761 tggtgagctg gacgtggcgc atcaaggtgc tgatgcatct ggaaaccgaa ctgatgggca
    38821 ccgtgcgcga acgtgcggaa gatgaagcaa tcaacgtctt tgcccgtaac ctgcacgatc
    38881 tgctgatggc ggcccctgcc ggactgcgtg caacgatggg cctcgatccg ggtctgcgta
    38941 ctggggtaaa agtggcggtg gtcgatgcca ctggcaaact ggtggcgacc gacaccattt
    39001 acccgcacac cggacaggcc gcaaaagcag cgatgaccgt tgctgcgctg tgtgaaaaac
    39061 ataacgttga actggtagcg atcggtaacg gtacagcttc ccgcgaaact gagcgtttct
    39121 atctcgatgt gcagaagcag ttcccgaaag tgaccgcgca gaaagtaatc gtcagcgaag
    39181 caggcgcgtc ggtttactcg gcttccgagc tggctgcaca ggagttcccg gatctcgacg
    39241 tttcgctgcg tggcgcggtg tctatcgccc gccgtttgca ggatccgctg gcggagctgg
    39301 tgaaaatcga tccgaaatct atcggcgtag gtcagtatca gcatgacgtc agccagacgc
    39361 aactggcccg caaactggac gcagtagtag aagactgcgt aaacgccgtt ggcgtcgatc
    39421 tcaacactgc ttctgttccg ctgttaaccc gcgtggcggg cctgacgcgc atgatggcgc
    39481 aaaacatcgt tgcctggcgc gatgagaacg gtcagttcca gaaccgtcag caactgttaa
    39541 aagtgagccg tctggggccg aaagccttcg agcagtgcgc gggcttcttg cgcattaacc
    39601 acggtgataa cccgctggac gcgtctaccg ttcacccgga agcctatccg gtggtggaac
    39661 gcattctggc agcaacacag caggcactga aagatctgat gggtaacagc agcgaactgc
    39721 gtaacctgaa agcgtctgac tttactgatg agaaattcgg tgtgccgacg gtaaccgaca
    39781 tcatcaaaga gctggaaaaa ccgggtcgcg atccgcgtcc ggaatttaaa accgctcagt
    39841 ttgccgatgg cgtcgagaca atgaacgacc tgcaaccggg tatgatcctc gaaggcgcag
    39901 tgaccaacgt caccaacttt ggcgcgtttg tcgatattgg cgtgcatcag gacggcctgg
    39961 ttcacatctc ttcattgtcg aacaagtttg tggaagatcc gcataccgtg gtgaaagcgg
    40021 gcgacattgt gaaggtgaaa gtgctggaag tggatcttca gcgtaaacgt atcgccctga
    40081 ctatgcgcct ggatgagcag cctggcgaaa ccaacgctcg tcgcggcggc ggtaatgaac
    40141 gcccgcaaaa caaccgcccg gcagccaaac cacgcggtcg tgaagcgcag cctgccggta
    40201 atagcgcgat gatggatgcg ctggcggcgg caatgggcaa aaaacgttaa acgcccgtac
    40261 tggcctacgg ttcgaatttg cacgaaatcg tagggcagat aaggcgttca cgccgcatct
    40321 ggcaacgaac gccttgcctg acataaaagt gccggagaat atctccggca tttttattcc
    40381 acagccaaac tcataatata ttccggcaat atttatcatt tcattaacaa ctgaaacctt
    40441 aattaaacat tagccagtcc gggtaattca ctattcgaat tatattttcg ctgcgatata
    40501 accttgagcc acatcaacat tgagtcagat tattattcaa accaacattc gcacacattt
    40561 taagtattgc tgatagaaac cattctcatt atcattgtgt tgttgattat ttaatctctc
    40621 ctttgttggc aaatcatctg gtctcatgtc gctgtcaaac gccccatgag gtagttatcc
    40681 agttaatgag aaacaagtag gcacctatgc aatacactcc agatactgcg tggaaaatca
    40741 ctggcttttc ccgtgaaatc agcccggcat atcgccaaaa actgctttct cttggcatgt
    40801 tacctggctc ctcttttaat gtggtgcgcg tcgctccact cggcgacccc attcatatcg
    40861 aaacccgtcg tgtgagcctg gtattacgca aaaaagatct ggccttatta gaagtggaag
    40921 cggtttcctg ttaatacggt gataacaaca atgaaaaaat taaccattgg cttaattggt
    40981 aatccaaatt ctggcaagac aacgttattt aaccagctca ctggctcacg tcagcgtgta
    41041 ggtaactggg ctggcgttac cgtcgaacgt aaagaagggc aattctccac caccgatcat
    41101 caggtcacgc tggtggacct gcccggcacc tattctctga ccaccatctc atcgcagacc
    41161 tcgctcgatg agcaaatcgc ctgtcactac attttgagtg gcgacgccga cctgctgatt
    41221 aacgtggtgg atgcgtctaa ccttgagcgt aacctgtacc tgacgctaca actgctggaa
    41281 ctcggcattc cctgcattgt ggcactgaac atgctcgaca ttgccgagaa gcaaaatatt
    41341 cgtattgaaa ttgatgctct gtcggcgcgt ctgggctgtc cggtgatccc gctggtttca
    41401 acccgtggtc gcggtattga agcgctcaag ctggcgattg atcgctataa agctaacgag
    41461 aatgtggaac tggtacatta cgcacagccg ctactcaacg aagcagattc actggcaaaa
    41521 gtgatgcctt ccgacatccc gctgaaacaa cgtcgctggc tgggcctgca aatgctggaa
    41581 ggcgatatct acagccgcgc ctacgccggt gaagcgtcgc agcatcttga tgccgccctc
    41641 gcccgtctgc gtaatgagat ggacgatccg gcgctgcaca ttgccgatgc gcgttaccaa
    41701 tgcattgctg ccatctgtga tgtggtaagc aacaccctga cggcagaacc cagccgtttc
    41761 accactgcgg tagataaaat cgtgctcaac cgtttcctcg gcctgccgat tttcctcttt
    41821 gtgatgtacc tgatgttcct gctggctatc aacatcggcg gggcgttaca gccgctgttt
    41881 gacgtcggct ccgtggcgct atttgtgcat ggtattcaat ggattggcta cacgctccac
    41941 ttcccggact ggctgactat cttcctcgcc caaggactgg gtggcggtat taacaccgtg
    42001 ctgccactgg tgccgcagat cggcatgatg tacctgttcc tctccttcct tgaggactcc
    42061 ggctatatgg cgcgtgcggc gtttgtgatg gaccgcctga tgcaggcgct gggcttgccg
    42121 gggaaatcct ttgtaccgct gatcgttggt ttcggttgta acgtaccgtc ggtaatgggt
    42181 gcacgtacgc ttgatgcacc gcgtgaacgt ctgatgacca tcatgatggc accgtttatg
    42241 tcctgcggcg cgcgtctggc tatcttcgca gtatttgcgg ctgccttctt cgggcagaac
    42301 ggtgcgctgg cggtcttctc gctgtatatg ctcggtatcg tgatggcggt gctgactggc
    42361 ctgatgctca agtacaccat catgcgcggt gaagcgacgc cgtttgtcat ggagctgccg
    42421 gtctaccatg taccacacgt taaaagcctg attatccaga cctggcagcg cctgaaaggc
    42481 ttcgttctgc gtgctggtaa agtgattatc atcgtcagca ttttcctgag cgctttcaac
    42541 agcttctcgt tgagcgggaa aattgtcgat aacatcaacg actcggcgct ggcttccgtc
    42601 agccgggtga tcaccccggt cttcaagccg attggcgtgc atgaagataa ctggcaggca
    42661 acggttggcc tgtttacggg cgcaatggca aaagaagtgg tggtgggtac gctcaacacc
    42721 ctctacaccg cagaaaatat tcaggacgaa gagttcaatc cggcggaatt taacctcggt
    42781 gaagagttgt tcagcgcggt agatgaaacc tggcagagcc tgaaagacac cttcagcctt
    42841 agcgtactga tgaaccccat tgaagctagc aaaggcgacg gcgaaatggg taccggggcg
    42901 atgggtgtga tggatcagaa attcggtagc gcagctgccg catacagcta tctgattttc
    42961 gtcctgctgt atgtaccgtg catctcggtg atgggagcca tcgcccgtga atcaagccgt
    43021 ggctggatgg gcttctccat cctgtggggg ctgaatatcg cttactcact ggcaacattg
    43081 ttctatcaag tcgccagcta cagtcagcac ccaacttaca gcctggtgtg cattctggcg
    43141 gtaatcctgt ttaacatcgt agttatcggc ctgctgcggc gcgcacgcag tcgggtggat
    43201 atcgaactgc tggcaacgcg caaatcggta agcagttgct gcgcagccag caccaccggt
    43261 gattgccatt aatggcttca cttattcagg tacgcgattt gctggcgtta cggggccgta
    43321 tggaagcggc ccagataagc cagacattga acacgccgca gccaatgatt aacgccatgc
    43381 tgcaacagct ggaaagcatg ggcaaagccg tgcggattca ggaagaacct gacggctgcc
    43441 tctctggcag ttgtaaaagc tgcccggaag gcaaagcctg tctgcgcgag tggtgggcgc
    43501 tgcgttaacc atactccatc gcctgttttg aaaagcccgg tatgcgtttg catccgggct
    43561 tttttgcgtg cggctttcca taaaaatgca attcttgcag cgcgacgtaa gttcctctga
    43621 aagcgtctcg cagggatgaa aactggctaa tgcacaggtg tggagtggcg cgtagagtcg
    43681 cggcattcaa acaacaggtg aaggaacgcc atgagtaaaa agcagagttc caccccacat
    43741 gatgcgctgt tcaaactctt tttacgccaa ccggacacgg ctcgcgattt tcttgcattc
    43801 catttaccgg cccccattca cgcgctctgt gatatgaaaa ccctcaagct ggagtcgagc
    43861 agctttattg atgacgatct gcgtgaaagc tactccgatg tgctgtggtc ggtgaaaacg
    43921 gaacaaggac caggatatat ctattgtctg attgaacatc aaagcacctc aaacaaactg
    43981 atcgcatttc gcatgatgcg ttacgccatt gccgcaatgc aaaaccacct ggatgccgga
    44041 tacaaaacgt tgccgatggt ggtgccattg ttgttttacc acggtattga aagcccctat
    44101 ccctattcgc tgtgttggct ggattgtttt gccgatccca acctggcaag gcagctttat
    44161 gcctctgcat ttccgctgat tgatgtcacc gtcatgcctg atgatgaaat catgcagcac
    44221 cgacgtatgg cgctgctgga gttaattcaa aaacatattc gtcaacgcga cctgatgggg
    44281 ctggtagagc aaatggcctg cttattaagt agtggatacg ctaatgacag acaaatcaaa
    44341 gggctgttta attacatact gcaaactggc gacgctgtac gttttaacga ttttatcgac
    44401 ggcgttgccg aacgttcacc gaaacacaag gagagtttaa tgactattgc ggaaagattg
    44461 cggcaggagg gggaacaatc caaagccctg catatagcca aaataatgct tgaatccgga
    44521 gttcctcttg cagacatcat gcgctttacc gggctgtcag aagaagagtt ggctgcggcg
    44581 agtcagtaaa gttctgtctc gccatttcaa aagccaccta caccctctgc ttcaacgcca
    44641 ccagcaggtg acaaaactcg gccggatgcg aaataaatgg cgcatgggcc gctttggcga
    44701 agatatatga ttcgctgtga ggccaaagtt tatccagcat cggcaccact ttgcgcggca
    44761 ccagaccgtc gagatagcca tacaatcgca aaaacggcat ggacacgttt tgcagcggct
    44821 gacggagatc gaccgttttc aggatttcca gcccgccatt aagcacgtca acctccggca
    44881 tcggtaacgc cagaacggtt ttcttcaacg cccgagcatc ctggcgcgcc gtttcagtcc
    44941 ccatggtttg taacgccagg aaccgctcca ctgtacgctg aaaatcatca ctgagttgct
    45001 gctgaaatcc cgccagcacg tccggtttta tccccggcca ctcgtcacga gcactaaaac
    45061 aaggtgacga cgccacggtg accagcgcct gaacacgctc gggatgggtt aacgcaatct
    45121 ggcttgccac cagcccgccc agactccagc ctaaccaaat ggctttatca ggtgcctgtt
    45181 gcagcacggc ttcggccata tcagcaagtg acagcgcacc aaatccccgg ctacgcccga
    45241 agccgggcag gtcaacaagg tgcagcgtaa aatgcgagct aagttcctcg tcaatgcaac
    45301 gccacacttc ggcattcagt ccccatccgt gcagcagcac aagatgaaca ttcccctgac
    45361 ctttggtctg ccaccagatg ttattcatcc gctattgttc tcttttgact tacaaggatg
    45421 aacatatgct aacagtaccg ggattatgct ggctatgccg aatgccactg gcgttaggtc
    45481 attgggggat ttgttcggtc tgttcacgcg ccacccgcac agataaaacg ttatgcccac
    45541 aatgtggatt acccgccaca cactcccatc ttccctgcgg tcgctgcctg caaaaaccgc
    45601 cgccctggca aagactggtc acggttgccg actatgcgcc gccgttaagt ccgcttatcc
    45661 accagcttaa attttcccgg cgcagtgaaa tcgccagcgc cctgtcacgt ctgttactat
    45721 tggaagtctt acacgctcgt cgcaccaccg ggttgcaatt gccggatcgc atcgtcagcg
    45781 ttccgttatg gcagcggcgt cactggcgtc ggggatttaa tcagagcgat ttgctgtgtc
    45841 agccgttatc acgctggttg cactgccaat gggatagcga agccgtcaca cgtacacggg
    45901 ccactgcgac ccagcatttt ctcagtgccc ggctgcgcaa gcgcaacctg aaaaatgcct
    45961 ttcgtcttga attgcccgtg caaggtcgcc atatggtgat tgtggatgat gtcgttacca
    46021 ccggaagtac cgtcgcagag attgcgcagt tgcttttacg caatggtgcg gcggctgtcc
    46081 aggtctggtg cctttgtcga accttgtaga gcctcgatga tgggcgtatt ataaccaact
    46141 aaaatagtca actattaggc cattactatg atccgtattt ccgatgctgc acaagcgcac
    46201 tttgccaaac tgctggcaaa tcaggaagaa gggacacaaa tccgcgtatt tgtgattaac
    46261 cctggcacgc ctaacgctga atgtggcgtt tcttattgtc cgccggacgc tgtggaagcc
    46321 accgacacag ccctgaaatt tgacctgctg accgcgtatg ttgatgagtt aagcgcacca
    46381 tacctggaag atgcagagat cgattttgtt accgaccagt tgggttccca gttaacgctg
    46441 aaagccccga acgccaaaat gcgtaaagtg gcagacgatg caccgctgat ggagcgcgtg
    46501 gagtatatgc tgcagtcgca gatcaaccca cagcttgctg gtcacggtgg tcgcgtttcg
    46561 ctgatggaaa tcaccgaaga cggttacgcc attctgcaat ttggcggcgg ctgtaacggt
    46621 tgttccatgg tcgatgtgac gctgaaagaa gggatcgaga agcagctgct gaacgaattc
    46681 ccggagctga aaggtgtgcg cgatctcacc gaacaccagc gcggcgaaca ctcctactac
    46741 taagttatcc cctcttttgt agattgcccg atgcgacgct aaagcgtcat ttcgggccta
    46801 cgttgaacat gtgccagacg ttggcgcagc attgctttgt caaatcctcg gttcgtttcc
    46861 ccgcgataat atgaccaacc tctcataatt taaatttacc ccgctctggt gattctcaaa
    46921 cgccagatgt tacccgtatc attcacatgg gtaccaaaca tactcctgac atctgactac
    46981 aataattagt tttagtgggt atcagtcgtg gtgccgcaat atctctgttc ccgattggga
    47041 taattagagt ttgtcgtcag aaaattgacg ttacccataa caaatgaaag gccaggtaaa
    47101 tcatgccatt agtcattgtt gctatcggtg taatcttgtt gttgctcctg atgatccgct
    47161 tcaaaatgaa cggcttcatc gctctcgtcc tcgtggcgct tgctgttgga ttaatgcaag
    47221 gaatgccgct ggataaagtt attggctcca tcaaagccgg tgtcggcggg acgctcggta
    47281 gccttgccct gatcatgggt tttggcgcaa tgctgggcaa aatgctggca gactgcggtg
    47341 gcgcacaacg tatcgccacc acgctgattg ccaaatttgg taaaaaacac atccagtggg
    47401 cggtggtact gaccggtttt accgttggtt ttgccctgtt ctatgaagtg ggctttgtgc
    47461 tgatgctgcc gctggtgttt accatcgcgg cttctgcgaa tattccactg ctgtatgttg
    47521 gtgtaccaat ggcggctgca ctgtctgtga cccacggctt cctgccaccg catccgggtc
    47581 cgactgcgat tgccaccatt ttcaatgccg atatgggtaa aaccctgctg tacggtacta
    47641 ttctggcaat cccgaccgtg attctcgccg gtccggttta cgctcgcgtg ttgaaaggta
    47701 tcgataagcc aattccggaa ggtctctaca gcgcgaaaac cttcagcgaa gaagagatgc
    47761 cgagctttgg cgtcagcgtc tggacctctc tggtgccggt agtactgatg gcgatgcgtg
    47821 cgattgccga aatgatcctg ccgaaaggtc acgctttcct gccggtagcg gagttcctcg
    47881 gtgacccggt aatggcaacg ctgattgccg tgctgattgc gatgttcacc tttggtctaa
    47941 accgtggtcg ttcaatggat cagattaacg acacgctggt ttcttccatc aaaatcattg
    48001 cgatgatgct gttgatcatc ggtggtggcg gtgcgttcaa gcaggtgctg gtagacagcg
    48061 gcgtggacaa atacattgct tccatgatgc acgaaaccaa catttctccg ctgctgatgg
    48121 cctggtcgat tgctgccgta ctgcgtatcg cgctgggttc cgcaaccgtt gcggcaatca
    48181 ctgcgggtgg tatcgcggca ccgctgattg caacgacggg tgttagcccg gagctgatgg
    48241 ttattgcggt tggttccggt agtgtgattt tctctcatgt gaacgatccg ggcttctggc
    48301 tgttcaaaga gtactttaac ctgactatcg gcgagaccat caaatcctgg tcgatgctgg
    48361 aaaccattat ctcggtgtgc ggtctggtag gctgtctgct gctgaatatg gtgatttgat
    48421 aacactgact gccggatgcg gcgtgaccgc cttatccggc ctacgattcg ggatgaatta
    48481 gtaggccgga taagacgcgt caagcatcgc atccggcatc aaccgcactc tacttcttct
    48541 tcgctgcagc tctgcgccgt ctgtccaaat ccttcagcaa cttgttcacg ccatcatcgg
    48601 caaacatcga ctcaagcgtt gcggaaagct tgcgtcgcca gtttttatac tggtaactgg
    48661 tgccaggaat attcaccggt tcggccatat ccagccagtc ttccggctgt agtcctaaca
    48721 gagcactgtt actgtcggca atgtagcgct gcaaaccacg gttcagcgtc ggcgtcatcg
    48781 acatcaacga tgccttatgc ccggcacgtt tcggcagaca accatattta tgcagtgcat
    48841 ccagcagccc ttgcttcgcc agttcgcgat cctgatacag accgcgcagt accacttcat
    48901 ccggatacag ccccagggtt ttgcccagcg ttagatcccc gctctcccag taaccgcgca
    48961 gcgttggcag gtcatgtgtc gccgcaaccg ccatcgactg ctccggatac gctttcggtg
    49021 cacggaacgt cttctcgtgg tcgttttcga aatagagcac tttgtaagag tacacaccgc
    49081 tgctgcgcag cttaccgaca atctctaccg gtacggtacc gagatcttca ccaatcacca
    49141 tacagcgatg acgtttactt tcgagtgcca gaatcgagag cagatcatcc accggatagt
    49201 gaacatacgc gccctgatct gccgtctcgc catacggtat ccaccacaaa cgcagcatcg
    49261 acatcacatg gtcaattcgt aatgcgccgc agttttgcat attggcacgc aacagctcga
    49321 taaacggttc ataggcacgc gcggtgatga tatgcgggtc cattggcggt aatccccagt
    49381 tctgccccaa cgggccgagg atatccggcg gcgcgccaac cgatgctttc aggcaatata
    49441 gttcacggtc acaccaggtt tccgccccac cttccgctac gccaaccgcc agatcacgat
    49501 acaagccaat cggcatttca tagccctggc ttatctccca gcaggcggca aactggctgt
    49561 aagccagcca ctgcaaccag agataaaaat cgacgtcatc acgatgttct tcgcagaact
    49621 gacgcacttc tggtgaatcc acgttctgat acatctctgg ccatgcaggc cagccccagc
    49681 gcatttcgtc ctctttcact tgctgggcat gtagcgcatc aaaggctgcc tgccagaaca
    49741 ggctgtcgcc ctgctctgca acaaactggc gaaacgcggc catctgctca tcatcacgtt
    49801 gcgcgaaacc tttccacgcc attcgtaatg ctgtcatttt tagggcggta accgtggagt
    49861 aatcgaccca gtcggcatcg cgcgcctgtt gcagcgtctg ttgcgtggtc ggcaactgcc
    49921 accaggcctg agcctcttcg ctaagatgga aatcttcaac ggcgttaacg tcgatataaa
    49981 tcacattcag ccaacggcga gaagacgggc tgtatgggct ggcgctctcc ggatttgccg
    50041 gatagagcgc atgaatcggg ttcaggccaa tgaacgaccc gccacgtttt gccacatcca
    50101 ccagcatcgc tttgagatcg ccaaaatccc caatacccca gtttttttcc gatcgcagcg
    50161 tataaagctg aacgcaggca ccccacagct tttgtttatt cagcaacgcc tgcggttcgt
    50221 aacagcgttt cggggcgaca atcacccggc aatgcgcgcg ctggtcgtcc tgggtgagtg
    50281 tcagcgtgtg ataaccttcc ggcagcttcg tcggtagatt gaacgctttg ccccccgtta
    50341 catggccttt gtactgcgtt ccttcttcgg tggtcagcag ccagctatat tcgccgctgc
    50401 cctccaccac catcggcatt tttttgccgc tggtataaac catgacattc gggactggcg
    50461 ttaccgccac tttcgtggcg gtacgttgat gcatcgcgtc aagcaaacgc cgtttggttt
    50521 cggcgctaat cgactgcggt ttaccgtggg cattgatgta attggggcta atccccgccg
    50581 ccagcgcggc attatccaga cgtttgcttt ccatcgagct tccttagcgt tttgcctgcc
    50641 agatacgagc ctgataatcg cgaatagagc gatccgagct aaacataccg cagcgggcgg
    50701 tattgaggat cgccgcgcga gtccaggcct cctggtcgcg gtacagcaca tccacctgct
    50761 tttgtgcctc tacataggct gcgaaatccg ccatcaccag atacggatcg ccgccctgtt
    50821 tgccgatact gtgcagcatc tggtcgaagg catgcttatc gccgtcgctg tatttaccgc
    50881 tttccagctc tttcaatact gcgtccagca ccttatcttt cttccgccat ttcaccgggt
    50941 cgtagccttt ggccagaatt gccttcactt gttccacggt atgaccaaaa ataaagatat
    51001 tttcttcacc gactttctcg gcgatttcaa cgttcgcccc atccagcgta ccgacagtaa
    51061 gcgcaccatt gagcgccagt ttcatattgc cggtaccgga agcttcttta cctgcagtcg
    51121 aaatttgttc ggagatatcc gccgccggga tcagtttttc cgccgccgaa acgcaataat
    51181 ccggcaggaa caccaccttc aacttatcgc caaccagcgg atcgttgttg atcacgtcag
    51241 ccactttgtt gatcgcaaag ataatattct tcgccaggta gtagcccggt gccgctttcg
    51301 cgccgaagag gaagacgcgc ggtacgcgat cagcctgcgg gttttcacga atttctttgt
    51361 acaacgccag aatatgcagc agattcaggt gctggcgttt gtactcatgc aaacgtttga
    51421 tctgaatatc gaaaatcgcc tgtggattga tctcaatacc ggtacgaact ttcacaaact
    51481 ccgccagacg gactttattc gcctgcttga tctcgcgata ttgctgacgg aatttcgcat
    51541 catcagcgaa tttttccaga ttgatcagct gatcgagatc gttagcccac tctttttgca
    51601 gtgatttatc caacagagcc gccagtgccg ggttgcactg tttgatccag cgacgtgggg
    51661 taataccgtt ggtgacgtta tggaatttgt tcggccatag ctggtgatat tccgggaaca
    51721 gatctttcac caccagatcc gagtgcagcg ccgcaacacc gttcaccgcg aaaccgccaa
    51781 ccacacacag gttcgccata tgcacttgtt tgtcgtgcac caccgccagt ttggcccaca
    51841 ctttttcatc gcccggccag gttttctcta ccagcgtttt aaagcgagta ttaatttcgt
    51901 taataatctg catatggcgc ggcagtaagc ctttcaccag tttcacctcc cagcgttcca
    51961 gcgcttctgg catcagggta tggttggtgt aagcgaaagt tttgctggta atggcccagg
    52021 cgtcatccca gctcatctgg tgctcatcga tcagcacgcg cagcagttct ggaatcgcga
    52081 tagttgggtg ggtatcgttc agctgaataa cttcgtaatc cgccagttcg tgcagtttac
    52141 gccccgccag atgatgacga cgcaaaatat ccgctaccga acaggcacac tggaagtact
    52201 gctgcatcaa gcgcagcttt ttaccggcag tatggttgtc gtttggatag agaactttgg
    52261 tcagtttttc cgcattgatg ccctgctgtt cggcacgcag gaaatcaccg tcgttaaatt
    52321 tagtcagatc aaacggatgc gcgtgcgtcg cctgccacag acgcagcggc tgcgccacgc
    52381 cattacgata gccgacaacg gggagatccc acgcttgacc ggtaatggta aactccggct
    52441 cccagcgtcc gtctttcgtc actttaccgc caatccctac ctgcacatcc agtgcttcgt
    52501 tgtggcggaa ccacgggtag ttactgcgat gccagtcatc cggcgcttca acctgtttgc
    52561 catcgacaaa agactggcgg aacaaaccat attgatagtt cagaccgtaa cccgtcgcag
    52621 actgaccgac agttgccatt gagtcgagga agcacgccgc cagacgtccc agaccaccgt
    52681 tacccagcgc cgggtcgatc tcttcttcca gcaggtccgt cagattgatg tcataagcct
    52741 tcaacgaatc ctgtacatcc tgataccagc cgagattcaa caggttgttg cccgtcaggc
    52801 gaccaatcaa aaactccatt gagatgtagt taacatgtcg ctgattcgcc accggcttgg
    52861 cgaatggctg agcacgcagc atttcggcca gtgcttcact cactgctagc caccactggc
    52921 gaggagtcat ttcagccgca gaatttaagc cataacgctg ccactgacgt gaaagcgctt
    52981 cctgaaattg cttatcgtta aaaataggtt gtgacatagg agttccactt ttcttagatt
    53041 ttcaacacaa cgttatcgct agtttgccag gctcgatgtt gaccttcctc atcctgcggg
    53101 ggattaggca gggaggagtt gcggggatga gcaaggaaat gtgatctcaa ccacttaaag
    53161 ctagtgcaaa ccacaggatt agcagcaaat caatgcaata cagcgcagaa aatctgtatc
    53221 taagtgcaaa aaatggccgt tgcgtatttt caaaaagcgg aaggtaactc tataaattaa
    53281 gtaaaggagt gaaacagttt cacaagtaaa atatccagtg tgctccatct cattcttaat
    53341 agatttatta agatcatctt tttagatggc actttcatca ggaatgaaga agaaaccctt
    53401 gcttaaatga atctgatgaa cataagggaa accagtattc acgctggatc agcgtcgttt
    53461 taggtgagtt gttaataaag atttggaatt gtgacacagt gcaaattcag acacataaaa
    53521 aaacgtcatc gcttgcatta gaaaggtttc tggccgacct tataaccatt aattacgaag
    53581 cgcaaaaaaa ataatatttc ctcattttcc acagtgaagt gattaactat gctgattccg
    53641 tcaaaactaa gtcgtccggt tcgactcgac cataccgtgg ttcgtgagcg cctgctggct
    53701 aaactttccg gcgcgaacaa cttccggctg gcgctgatca cgagtcctgc gggttacgga
    53761 aagaccaccc tcatttccca gtgggcggca ggcaaaaacg atatcggctg gtactcgctg
    53821 gatgaaggtg ataaccagca agagcgtttc gccagctatc tcattgccgc cgtgcagcag
    53881 gcaaccaacg gtcactgtgc gatatgtgag acgatggcgc aaaaacggca atatgccagc
    53941 ctgacgtcac tcttcgccca gcttttcatt gagctggcgg aatggcatag cccactttat
    54001 ctggtcatcg atgactatca tctgatcact aatccagtga tccacgagtc aatgcgcttc
    54061 tttattcgcc atcaaccaga aaatctcacc ctggtggtgt tgtcacgcaa ccttccgcaa
    54121 ctgggcattg ccaatctgcg tgttcgtgat caactgctgg aaattggcag tcagcaactg
    54181 gcatttaccc atcaggaagc gaagcagttt tttgattgcc gtctgtcatc gccgattgaa
    54241 gccgcagaaa gcagtcggat ttgcgatgac gtttccggtt gggcgacggc actacagcta
    54301 atcgccctct ccgcccggca gaatacccac tcagcccata agtcggcacg ccgcctggcg
    54361 ggaatcaatg ccagccatct ttcggattat ctggtcgatg aggttttgga taacgtcgat
    54421 ctcgcaacgc gccattttct gttgaaaagc gccattttgc gctcaatgaa cgatgcactc
    54481 atcacccgtg tgaccggcga agaaaacggg caaatgcgcc tcgaagagat tgagcgtcag
    54541 gggctgtttt tacagcggat ggatgatacc ggcgagtggt tctgctatca cccgctgttt
    54601 ggtaacttcc tgcgccagcg ctgccagtgg gaactggcgg cggagctgcc ggaaatccac
    54661 cgtgccgccg cagaaagctg gatggcccag ggatttccca gcgaagcgat tcatcatgcg
    54721 ctggcggcag gcgatgcgct gatgctgcgc gatattctgc ttaatcacgc ctggagtctg
    54781 ttcaaccata gcgaactgtc gctgctggaa gagtcgctta aggccctgcc gtgggacagc
    54841 ttgctggaaa atccgcagtt ggtgttattg caggcgtggc tgatgcaaag ccaacatcgc
    54901 tacggcgaag ttaacaccct gctagcccgt gctgaacatg aaatcaagga catcagagaa
    54961 gacaccatgc acgcagaatt taacgctctg cgcgcccagg tggcgattaa cgatggtaat
    55021 ccggatgaag cggaacggct ggcaaaactg gcactggaag agctgccgcc gggctggttc
    55081 tatagccgca ttgtggcaac ctcggtgctg ggtgaagtgc tgcactgcaa aggcgaattg
    55141 acccgctcac tggcgctaat gcagcaaacc gaacagatgg cacgccagca cgatgtctgg
    55201 cactacgctt tgtggagttt aatccagcaa agtgaaattc tgtttgccca agggttcctg
    55261 caaaccgcgt gggaaacgca ggaaaaagca ttccagctga tcaacgagca gcatctggaa
    55321 cagctgccaa tgcatgagtt tctggtgcgc attcgtgcgc agctgttatg ggcctgggcg
    55381 cggctggatg aagccgaagc gtcggcgcgt agcgggattg aagtcttgtc gtcttatcag
    55441 ccacagcaac agcttcagtg cctggcaatg ttgattcaat gctcgctggc ccgtggtgat
    55501 ttagataacg cccgtagcca gctgaaccgt ctggaaaacc tgctggggaa tggcaaatat
    55561 cacagcgact ggatctctaa cgccaacaaa gtccgggtga tttactggca aatgaccggc
    55621 gataaagccg ccgctgccaa ctggttgcgt catacggcta aaccagagtt tgcgaacaac
    55681 cacttcctgc aaggtcaatg gcgcaacatt gcccgtgcac aaatcttgct gggcgagttt
    55741 gaaccggcag aaattgttct cgaagaactc aatgaaaatg cccggagtct gcggttgatg
    55801 agcgatctca accgtaacct gttgctgctt aatcaactgt actggcaggc cggacgtaaa
    55861 agtgacgccc agcgcgtgtt gctggacgca ttaaaactgg cgaatcgcac cggatttatc
    55921 agccattttg tcatcgaagg cgaagcgatg gcgcaacaac tgcgtcagct gattcagctt
    55981 aatacgctgc cggaactgga acagcatcgc gcgcagcgta ttctgcgaga aatcaatcaa
    56041 catcatcggc ataaattcgc ccatttcgat gagaatttcg ttgaacgtct gctaaatcat
    56101 cctgaagtac ctgaactgat ccgcaccagc ccgctgacgc aacgtgaatg gcaggtactg
    56161 gggctgatct actctggtta cagcaatgag caaattgccg gagaactgga agtcgcggca
    56221 accaccatca aaacgcatat ccgcaatctg tatcagaaac tcggcgtggc ccatcgccag
    56281 gatgcggtac aacacgccca gcaattgctg aagatgatgg ggtacggcgt gtaagtttag
    56341 ccggataacg cgccagatcc ggcttacatc tctgcatcat tcaatgctca cccgcgttac
    56401 gccatctgtt tctatcaaac taaaccgcac cggcaagaaa cgctccacca ccgcgatatt
    56461 ggtcagcaga tggcatgagg gatgggcgac cgtaaattcc cccgcgcccg ccagcgccat
    56521 cggtagcacc agttggtcag caagatattc ccccaccgcc gccgtgcttg ccaggtagcg
    56581 tttcacctct ttcaccaact gtgccgcaac cacctcggca ctgacgcgct tttcaccgac
    56641 gacaaaaaag cgttcggtga tattttcact ttcgacttca agcgagacgg tattacccgg
    56701 cccctggtcg cgcggcaggt tatgaatatt ctgttcatgc agggaaaaac tccccgccag
    56761 tgtagcgatt tcacgctcag caacatggcg cggcacacca gctaatagaa cttctccacg
    56821 catctgcaca atgttcccgc gctcgccaag ttgcaaggtg ttaaacgatg ccacgggcga
    56881 gacttccgtt gccaccacac cgcctccggc agggtaaaaa ccgtggcgta acagcgtggt
    56941 ttgctgatga attcctattt tcgccagcag cggctccagc acccggcgga taaaatccgc
    57001 aggcggcgcc gacgggttat cggtgccgcc gctcacttca acacgcgaag gtccatcggc
    57061 aaaccacagc gcgggcagca ccgtttgcag caccagcgta caacttccgg cgctaccgat
    57121 agcaaagcgg taatcgccgc cgcgcacggt gccgggccgg aagagcagac gctgcgaccc
    57181 cagctccgcg ccttccacgg ttgctccgca aatttccgtc gccgccttta ccgcggtcag
    57241 atgctggcgc aacagccccg gtttcgcccg cccggcacga atgctggtga tggtaaatgg
    57301 ctggccggtt atcatcgaca ggctcagcgc cgagcgcagg atctgcccgc caccttcgcc
    57361 ctgtgcgcca tccagcgcaa tcatcctttt catcatttat ccttttacgc acaccacctg
    57421 acgcagggta tagataactt ccaccagatc gctttgtgcc gccatcaccg catcaatatc
    57481 tttatacgcc atcgggattt cgtcgatcac ttcggcatct ttacggcatt ccacatgcgc
    57541 ggtggcacga atttgatctt ccacgctgaa cagttttttc gctttagttc ggctcattac
    57601 ccgcccggca ccgtggctgc acgaacagaa cgactcttca tttcccagcc cacggacgat
    57661 aaagcttttt gctcccatcg aaccgggaat aattccatat tgaccagcac gcgcagacac
    57721 cgcgccttta cgcgtcacgt agatctcttc accaaagtgc tgttcttttt gcacatagtt
    57781 gtggtgacag ttgatctctt ccatcgccag cgtttgtggc tgtctgaccg ttttctgcgt
    57841 aatgctctgc aatgccgtta ccacgttttc catcatcgca tcgcggttaa ggctggcaaa
    57901 aagctgcgcc caggccacgg ctttcaggta atcatcaaag tattccgtac cttccataaa
    57961 gtacgccaga tcacgcgacg gcaacgtctc aagcgtttcc tgcatctctt tttgtgccag
    58021 atcgataaag taagtcccga tggcgttacc aattccgcgt gaaccggagt gcagcataat
    58081 ccacacctgg tccgactcat caaggcagat ttcaataaag tggttaccgg ttcccagcgt
    58141 tcccaggtgt ttatagttat tggtattcag gaaacgggga tatttttgcg ttaaccactg
    58201 ataaccggct tcaagctcag cccatttagc atcgacgtta acaggtggat tttcccaggc
    58261 acctttatca cgtttacaac ggccagtggt acgcccgtgc ggcacggccg tttcaatcgc
    58321 ctgacgcagc tctgccaggt tttcaggcag gtcttccgcc gttaacgcgg tacgcagcgc
    58381 gttcattcca cagccaatat ccacgcccac cgccgccgga ataatcgccc ctttggtcgg
    58441 gatcacgcta ccaatggtgg aacctttacc caggtgtaca tcaggcatta ccgcaatatg
    58501 tttgaaaata aacggcatct tcgccgtatt aataagttgc tgacgcgcat cggcctctac
    58561 cggcacgcct ttggtccaca tttttaccgg ggcattttca gtggtcagta attcgtaatt
    58621 cattttgttt ttctcttttc gttgtttgct gtcctgataa ttgcaaccgt cgtgccagaa
    58681 aattaaataa gcagcttaat tttttaattc attgttttaa aaaagattat atctttacgt
    58741 ccgtaaccgg agatttcccg caaagccaat ttaccgataa tgaaatatcg tcttttataa
    58801 ggatatctaa gatgcgtaaa acagtggctt ttggctttgt cggtaccgta ctggattatg
    58861 ccgggcgcgg cagtcagcgc tggtcaaaat ggcgtccgac actctgttta tgccagcaag
    58921 aatcgttggt catcgatcga ctggaattgt tgcacgacgc ccgctcgcgc tcgctatttg
    58981 aaacgcttaa acgcgatatc gccagcgttt cgccagaaac agaagtggtg agcgttgaga
    59041 ttgaactgca taacccgtgg gatttcgaag aggtctacgc ctgcctgcat gatttcgccc
    59101 gtggttacga gtttcagcca gaaaaagaag actatttaat tcacatcacc accggtaccc
    59161 acgtcgcgca gatttgctgg tttctgctgg cagaagcgcg ttacctgccc gcccggctga
    59221 tacaatcttc acctccgcgc aaaaaagaac agccgcgcgg cccaggtgaa gtaacgatta
    59281 tcgatctcga tttaagccgt tataacgcca tcgccagccg ctttgccgag gaacgccagc
    59341 aaacgcttga ttttcttaag tccggcattg ccacgcgtaa cccccacttc aaccgcatga
    59401 ttgagcagat cgaaaaagtg gcgatcaaat cccgcgcgcc gattctgctt aacggtccaa
    59461 ccggcgcggg caagtcattt ctggcgcgac gcatcttcga gttaaaacag gcgcggcatc
    59521 agtttagcgg cgcgtttgtg gaagtgaact gcgccaccct gcgcggcgat accgccatgt
    59581 cgacgctgtt tggtcatgta aaaggcgcgt ttaccggggc gcgggaatct cgtgaaggtt
    59641 tattacgcag cgccaacggc ggaatgttgt ttcttgatga gattggcgaa ctgggcgcag
    59701 acgaacaggc aatgctgctg aaagccattg aagagaaaac cttttacccg tttggcagcg
    59761 atcgccaggt gagcagtgat tttcagctta tcgccggaac ggtgcgcgat ttgcgccagc
    59821 tggttgccga aggcaaattt cgcgaagatc tgtacgcgcg gatcaatctc tggaccttca
    59881 ccctgccggg tctacgccag cgccaggaag atattgaacc gaacctggat tatgaagtgg
    59941 agcgccacgc ctcactcact ggcgacagcg tgcgttttaa caccgaagcg cggcgcgcct
    60001 ggttggcttt tgcgacctct ccccaggcaa catggcgcgg taactttcgc gaactttctg
    60061 ccagcgtcac gcggatggcc acctttgcca ctagcggacg catcactctg gacgtggttg
    60121 aagatgagat aaaccgtctg cgctataact ggcaggagag ccgcccctcc gcgcttacgg
    60181 cgttgctggg cgcagaggca gaaaacatcg atctcttcga ccgtatgcaa ctggaacacg
    60241 ttatcgctat ctgccgccag gcaaagtcgc tttccgcagc cggacgccag ctttttgacg
    60301 tttcgcgcca gggcaaagcc agcgtcaatg acgcggatcg gctacgcaaa tacctggcgc
    60361 gttttggtct gacgtgggaa gccgtgcagg atcagcacag ctccagttga atatggtggt
    60421 ccgtcagcac ctgcatcacg cttactggcg gcggggcgtc ggtgtagacg gcatctacca
    60481 tgctgatgct gcccatattg accatcgcgt tacggccaaa tttcgagtga tcgacaacca
    60541 gcataacgtg gcgcgagttc tcaataatgg cgcgtttggt gcgaacttcg tggtaatcga
    60601 actccagcag cgagccgtcg ctatcgatgc cgcttatccc cagaatgccg aaatcaaggc
    60661 ggaactggga gataaaatcg agcgtcgctt cgccaatgat cccgccatcg cggctgcgta
    60721 attcgccacc ggcgagaatg atgcgaaaat cttcttttac catcaacgtg ttagcaacgt
    60781 tgagattgtt ggtgacaatg cgcaaattgc tgtgattgag cagtgcgtgc gctaccgctt
    60841 ccggcgtggt gccgatatcg ataaacagcg tcgagccatt ggggatttgc tccgccactt
    60901 tgcgggcgat gcgctctttt tcttcggtct gggtggcctt gcgatcgtgc cacggcgtgt
    60961 taaccgaact ggaaggcagc gccgcaccgc catgatggcg caggatcagg ttttgctccg
    61021 ccagctcatt gaggtcgcgg cgaatagtct gcgggctgac ggagaaatgc tctaccagct
    61081 cttcggtact gacataaccc tgctgtttaa ccagttcgat aataccgttg tgacgttgtg
    61141 tttgtttcat ttataaatcc ctggaattat tttcgttttc gcgcattgag cgaatcaaca
    61201 aaagccatcg ctaaacccac ggctaacccg gcgatgtgtg ctccgttcgc catcgacatc
    61261 ccaaacaaat caaaccatcc ggcgacaatc cagatcagcg caaagataat taacccacgt
    61321 tgcaggtaaa tgccactttg cggatcgcgt tcgccacgta gccagacgta gcccatcagc
    61381 gcatacacca cgccagaaag cccgccaaac cacggcccgc tgaatttttg ctgcacatag
    61441 ccgcttaaca gggcgctgat aagcgtaatg acaattagct taccgctacc gaggcgtttt
    61501 tccaccgcac cgccgagata ccaccaccag agcaggttaa agaggatatg catcagcgag
    61561 aagtgcatta acgcgtgggt gaagtaacgc cagaactcaa atttcagtgt tggatcgaat
    61621 ggccaggcca gccataacat cacttcctga tcgccgagaa tttgcatggc aataaacacc
    61681 accacgcagg cgatcatcat cacccaggtt accggacctg cgcgttcacg caaggcggca
    61741 aagaaaggat aacggcgata atgcaggcca ctgccggtat ggcctgcctg ccagctcgcc
    61801 gccagataac gcggatctgc cgggttttcg agaaaacgcg ccagctccgc ccgtacgcgc
    61861 tcggcctggg actcatccgc cagccagaca tcgctttggt tatgttgttg aatcgtgagg
    61921 ataacaccct gcgtcgccat gtaatcaaca aacgcctgcg ccacgcgggg gttagcaaaa
    61981 gaggtaatca tcaacatcgt tgctgtcgct tattccacac aaaaggggac agtataaagc
    62041 gttacgcgcc gtacgccacc tctgcgggaa actgacgttg ccaggcttca aagccgccgt
    62101 caatgctata gaccacatcg tagccctgtt gcagcagata ctgcgccgcg cctttgctgc
    62161 tattgccgtg ataacacatc accatcaccg gagtgtcaaa gtcgttatca cgcataaaag
    62221 cgcccagcgt gtcgttggtt aaatggaaag cctgcaccgc atgtcccatt gcgaaactct
    62281 gtggatcgcg aatatcgacc agcaccgcct ctttttcctg caacttctgg tgcgcgtcgg
    62341 caacgttaat acattcgaac tgatccatgc gtctctcttt ctttacaaac aagtgggcaa
    62401 atttaccgca cagtttacgt cgaagcggca gataaacgcc ataatgttat acatatcact
    62461 ctaaaatgtt ttttcaatgt tacctaaagc gcgattcttt gctaatatgt tcgataacga
    62521 acatttatga gctttaacga aagtgaatga gggcagcatg gaaaccaaag atctgattgt
    62581 gatagggggc ggcatcaatg gtgctggtat cgcggcagac gccgctggac gcggtttatc
    62641 cgtgctgatg ctggaggcgc aggatctcgc ttgcgcgacc tcttccgcca gttcaaaact
    62701 cattcacggt ggcctgcgct accttgagca ctatgaattc cgcctggtca gcgaggcgct
    62761 ggctgaacgt gaagtgctgc tgaaaatggc cccgcatatc gccttcccga tgcgttttcg
    62821 cctgccacat cgtccgcatc tgcgcccggc gtggatgatt cgcattggtc tgtttatgta
    62881 cgatcatctg ggtaaacgca ccagcttgcc gggatcaact ggtttgcgtt ttggcgcaaa
    62941 ttcagtgtta aaaccggaaa ttaagcgcgg attcgaatat tctgactgtt gggtagacga
    63001 cgcccgtctg gtactcgcca acgcccagat ggtggtgcgt aaaggcggcg aagtgcttac
    63061 tcggactcgc gccacctctg ctcgccgcga aaacggcctg tggattgtgg aagcggaaga
    63121 tatcgatacc ggcaaaaaat atagctggca agcgcgcggc ttggttaacg ccaccggccc
    63181 gtgggtgaaa cagttcttcg acgacgggat gcatctgcct tcgccttatg gcattcgcct
    63241 gatcaaaggc agccatattg tggtgccgcg cgtgcatacc cagaagcaag cctacattct
    63301 gcaaaacgaa gataaacgta ttgtgttcgt gatcccgtgg atggacgagt tttccatcat
    63361 cggcactacc gatgtcgagt acaaaggcga tccgaaagcg gtgaagattg aagagagtga
    63421 aatcaattac ctgctgaatg tgtataacac gcactttaaa aagcagttaa gccgtgacga
    63481 tatcgtctgg acctactccg gtgtgcgtcc gctgtgtgat gatgagtccg actcgccgca
    63541 ggctattacc cgtgattaca cccttgatat tcatgatgaa aatggcaaag caccgctgct
    63601 gtcggtattc ggcggtaagc tgaccaccta ccgaaaactg gcggaacatg cgctggaaaa
    63661 actaacgccg tattatcagg gtattggccc ggcatggacg aaagagagtg tgctaccggg
    63721 tggcgccatt gaaggcgacc gcgacgatta tgccgctcgc ctgcgccgcc gctatccgtt
    63781 cctgactgaa tcgctggcgc gtcattacgc tcgcacttac ggcagcaaca gcgagctgct
    63841 gctcggcaat gcgggaacgg taagcgatct cggggaagat ttcggtcatg agttctacga
    63901 agcggagctg aaatacctgg tggatcacga atgggtccgc cgcgccgacg acgccctgtg
    63961 gcgtcgcaca aaacaaggca tgtggctaaa tgcggatcaa caatctcgtg tgagtcagtg
    64021 gctggtggag tatacgcagc agaggttatc gctggcgtcg taaattaacg taaggtgatc
    64081 aggtcagatt tcaatctggc ctgagactga tgacaaacac aaaactgcct gatgcgctac
    64141 gcttatcagg cctacgtggt ttatgcaata tattgaattt gcatggtctt gtaggccaga
    64201 taagacgttc acgtcgcatc cggcatgaac aaagcgcact ttgtcaaaaa tctaacctac
    64261 tttttaattc agggaattac cgcaaagccc acgccatcat acccaacgta acaaaactca
    64321 ggcacgttcc ccactcgccc cgagaaaaat agcattaatg cgcccagcgc cagcataaaa
    64381 attttgagca gaaggtaaat tgttggcgtg ataaggatat tacaaacttc aataataccg
    64441 gcaagtccga cacccagcat ggcaataacc accgccaaaa attgcgccag tatggggatg
    64501 ccgaaaaaag tcattaccag cgaggtcaaa atccattttc tgttttgcat tattctttcc
    64561 attctttttg aatggtgaaa ttatactccc cgagtcccct tgccccttct ggacactttt
    64621 ccgaaatgat ggcggaaaaa aacgggaccc tttggccccg ttctatttat tggtgaactt
    64681 acaatctcac cggatcgata tgccagatat gatcggcgta ctctttgata gtacggtcag
    64741 aagagaagta gcccatattg gcaatgttca gcatcgcttt tgcggtccac tcttcctgaa
    64801 gctcgtagag ttcatcgact ttatcctgac aatcgacata gctgcgataa tccgccagta
    64861 cctggtagtg atcgccgaag ttgatcagcg aatcaaccag atcgcgatag cgacccggat
    64921 cttccggact gaatacaccg ctgccgattt gcgtcagcac ctgatgcagc tcctcatctt
    64981 tctcgtagta ttcacgcggt ttgtagccct gacgacgcag ttcttccact tcttccgctg
    65041 tgttaccaaa aataaagata ttgtcagcac cgacatgatc cagcatctcg acattcgcac
    65101 cgtccaacgt accgatagtc agcgcaccgt taagcgcaaa cttcatgtta ctggtgccgg
    65161 aagcttccgt ccctgccagc gaaatctgtt cagacagatc tgccgccgga atgatcaact
    65221 gcgccaggct aacgctgtag ttcgggatga acacgacttt cagcttatcg ccaatctgcg
    65281 gatcgttgtt gatcactttc gctacgtcat tgatcaaatg aataatgtgc ttcgccatgt
    65341 aataggccga agccgcctta ccgccaaaaa tattcacgcg cggtacccac ttcgcatccg
    65401 ggtcggcctt gatgcggtta tagcgggtaa tcacatgcaa cacattcatc aattgacgtt
    65461 tgtattcgtg aatacgtttg atttgtacat cgaacaacgc ctttggattc accaccacat
    65521 tcagctgctg ggcgatatac tctgccagac gctttttgtt ctccagcttc gcctgatgca
    65581 cagcgtgatt aaccattggg aaatcacagt gttgttgcag ctcattaagc aggctaaggt
    65641 cggtgcgcca gttacggccc aggtgttcgt ccagcacggc tgaaagcgat gggttcgcta
    65701 ccgccagcca gcgacgcggc gtcacaccgt tggtgacgtt ggtgaaacga cccgggaaga
    65761 ttttcgcaaa gtcggcaaac aacgattgca ccatcagatt agagtgcagt tccgatacac
    65821 cgttaacttt gtggctcaca acaaccgcca gccaggccat acgcacacga cgaccgttgg
    65881 attcatcaat gatcgacgcc cgtcccagca gatcggtatc gttcggatac tgttcctgca
    65941 aggttttcag gaaatagtcg ttgatttcaa agatgatctg caggtgacgc ggcagaattt
    66001 tacccagcat atcaaccggc caggtttcca gcgcctcgct catcagcgtg tggttagtgt
    66061 aggagaagac ctgacaacac acctcaaacg cgtcgtccca gctaaattgg tgctcatcga
    66121 tcagcagacg catcatctca ggaatcgaca gtaccggatg ggtatcattg agatgaatcg
    66181 cgattttatc cgccaggtta tcgtaggttt tatgcaactg ataatggcgg cttaaaatgt
    66241 cctgaatggt cgaggaaacc aggaagtatt cctgacgcag gcgcagctca cgcccggagt
    66301 aggtggagtc atccggatac agtacgcgag atacgttctc ggagtggttt ttatcttcca
    66361 ctgccgcgaa gtagtcaccc tggttgaatt taccgaggtt aatttcgcta ctggcttgcg
    66421 cactccacaa acgcagcgtg ttggtcgcgt cggtgtcgta accagggatt atctgatcgt
    66481 aagcgactcc cagaatctct tcggtttcaa tccagcgcgt ttttttacct tcctgctgaa
    66541 tgcgaccgcc aaaacggact ttatagcgcg tgttgtggcg tttgaattcc cacgggttac
    66601 cgtattccag ccagtagtct ggcgactctt tctggctacc gttaacgatg ttctgcttga
    66661 acataccgta gtcatagcgg atgccgtaac cgcgccccgg caaccctaac gtcgccagag
    66721 aatcaaggaa gcaagccgcc agacgtccca ggccaccgtt accgaggcct gggtcatttt
    66781 cttcatcaat cagctcttcg agatttaacc ccatcgcttc cagtgcgccc tgtacatctt
    66841 cgtaaattcc tagcgacaac atggcgttgg agagcgtacg gccaatcaaa aactccatcg
    66901 acaggtagta aacctgacga gtttcttgcg acaactgggc acggtttgaa cgtaaccagc
    66961 gctccacgag acgatcgcgc acagcaaata acgttgcgtt cagccattca tgtttattgg
    67021 cgacgaccgg gtcctttcca atcgtaaaca tcagcttgta agcgatagag tgcttaagag
    67081 cttctacgct aagcgtgggc gatgaatatg taaacggagc attcatatag gcgtttcctg
    67141 aaaactattt caagcgatag taaagctcac ggtacgactt cgccgcgacc tgccagctaa
    67201 aatccattgc catagcctga cgttgcacaa accgccacag tgaaggacgg gaccacagta
    67261 caaaagcacg tcgaatagcc cgtaacagcg accaggcatt actatcttca aagacaaacc
    67321 cactggcgac gccatctgca aggttctcaa gagaacagtc agaaaccgta tcagcaagcc
    67381 caccggtgcg ccgcactaac ggcagcgtac cgtacttcaa tccataaagt tgcgttaagc
    67441 cgcacggttc aaaacggctg ggcaccagaa tgacgtccgc gccgcccata atgcgatgcg
    67501 aaaatgcttc gtgatagcca atctgaacgc ccacctgacc ggggtattcc gctgccgccg
    67561 caaggaaacc ttcctgcagc accggatcgc ccgcgccgag tagcgccagc tgcccgccct
    67621 gctccagaag acccggtaag gcttccagca ccaggtcgag acctttctgg ctggtcagac
    67681 ggctcaccac tgcaaaaagc ggcactttat cgtcaacctt aagccccatt gcgatttgta
    67741 actggcgctt attttccgct ttatcttcca acgtatcgcg ggtgtaacgc gaggccaaca
    67801 gtaagtccgt ctctggactc cagattttct cgtccacgcc gttcagtacg ccggaaagac
    67861 gcccttcacg gtgacgctgt tgcaacagac cttccatacc gtaggcaaac tgcggttcgg
    67921 tgatctcgcg agcgtaggtt ggactgaccg ccgtaatgtg atcggcatag tacagaccgg
    67981 ccttcaggaa agagatttgt ccgttgaatt ccagcccatg aatattaaag aatgaccatg
    68041 gcaattggat gtcattcatg tgatgtgcat aaaacatgcc ttgataggcc aggttgtgca
    68101 cagtaaacac cgacttcgcc ggacgcccgc gcgccgccag atacgcaggc gcaaggcctg
    68161 catgccagtc gtgcgcatgc accacatcag gacgccagaa tgggtcaagc ccgctggcca
    68221 tttctgcccc aacccacccc agcagcgcaa aacgcaatac gttgtcggta taggcaaata
    68281 agttggtatc gtgatacggg cttcccggac gatcatagag atgcggcgcg tcaatcaggt
    68341 aaatgccaac cccgttgtaa tgaccgaaca acagcgtgat atgtccggcg aaggtatcac
    68401 gacgggatac tacctgcgca tcggtcacgc cacggcgaat atcgggaaat gcaggcaaca
    68461 gtacgcgagc gtcaacgccg tctgcgattt gtgctgcggg taatgcccca ataacatcag
    68521 ccagaccgcc ggttttaagc agcgggaaca tctctgaaca tacatgtaaa acctgcatta
    68581 tcgctcctgt ttatgcccta acttccgtag catttcgcgc gttaccagca cgatgccttc
    68641 ttctgaacga tagaaacgac gtgcatcttc ctctgcgttt tcaccaatca ccatgccttc
    68701 cggaataaca caagcacgat cgatgacgca gcggcgcaga cggcacgagc gacctaccca
    68761 tacttccggt aacaatacgg cggaatcaat gttgcagaat gaattcacgc gaacgcgcga
    68821 gaacagaacg gactgcacca ccaccgaacc ggagatcaca caaccgccgg aaaccagtga
    68881 gttaagggtc atcccgtggc taccggagcg atcctgcacg aatttcgctg gcggtaatga
    68941 ttcattgtag gtgcgaattg gccaattgcg atcgtacata tccagttccg gcaccacaga
    69001 ggccagatcg aggttcgctt tccagtaagc ttccagcgta cccacatcgc gccagtacgg
    69061 ctcggcatcc gggtcggatt gtacgcaaga gagcgggaac gggtgcgcat aggccagacc
    69121 ggcttcggtg atcttgggaa tcaaatcttt gccaaagtcg tggctggagt tctcatcgcg
    69181 atcgtcttct tccagcagtt catacagata gtcggcgtca aagacgtaga tacccatact
    69241 cgccagagat ttgctcggat cgttcggcat tgacggcggg ttagcaggtt tttcaacgaa
    69301 ttcgataatt ttatcgttct catcaaccgc cataacgcca aatgcggagg cttcttcaat
    69361 cggtactggc atacaagcaa cggtgcaacg tgcgcctttt tcgacgtgat cgataagcat
    69421 acgcgagtag tcttgcttgt agatatggtc gcccgccagg atcaccacgt attccgcttt
    69481 ataacggcgg ataatgtcga ggttttgggt gaccgcatct gcggtgccgc gataccagtt
    69541 ttcccctttc attctctgct gtgctggcag cagatcgaca aactcgttca tttcttcatt
    69601 gaagaatgac cagccgcgct gaatgtgctg caccagagtg tgggactggt actgggtgat
    69661 cacgcccata cgacggatcc cggagttgat gcagttagac agcgcaaagt cgataatgcg
    69721 gaacttaccg ccgaagtgta cggccggttt tgctcgctta ttggttaaat ccttcaggcg
    69781 ggtaccacgt cctcccgcca gtatcagggc aacagatttc aatggcagct ggcgcgccaa
    69841 cattaagtga tcgttcttct ctaaactaac catgactaac tcctttttta tcatctctgg
    69901 aacacacaca atccgtgtgc aggtccctgc cagacagccg taatcactgg gttatcctct
    69961 ccagcgaatg ggggaatggc gtgccactcc ccagcaggta aaacaatctc tgttacctca
    70021 agcgtggcgt taattgcgat caaaaagcga tccgagagca gaatttgcag ctgtttcggc
    70081 ccgttttgcc actcatccgt gcttaaaggt tgagcatatc gatttagcca acggacattg
    70141 ccgtcgcctt cttcccacca gcgattctcc accaaagcgg gaatgcgctt gcgcagatgg
    70201 attaacgcgg cggtaaatgc ggttaaacca ctgcttgcct gcgaccagtc caaccaggtt
    70261 aattggttat cctgacagta ggcattgtta ttgccatgct ggctgtgacc atgttcgtca
    70321 ccggccagta acatcggcgt accctgggag agcaacaacg ttgttaacag ggcgtgaatg
    70381 ctgtcgcgcc gccgttcaac caggtcaaga gaaccgccta acccttcttt accatgattg
    70441 ttactgtaat tgttgttggt cccgtcgcga ttttcttctc cgtttgcttc attgtgttta
    70501 tggttgaagc aaacgcagtc gcgaagcgta aaaccgtcat gcgcggtgac gagattaatc
    70561 gcggcactcg gcagacgacc attacgttta aaaacatcgc tggaggcagc aaaacgcccg
    70621 gcaaacgccc ccagaggcaa atcataatgt agccagaaac gacgggcagc atcgcggaaa
    70681 tgatcgttcc actcggcaaa cagcggcggg aaatttccca cctgataacc accaggagcg
    70741 atatcccacg gttcagcaat taacttcacc tgcgagagca ccgggcagtt ctggatagcg
    70801 gtaaacaacg gcgcatcctg acggaactct ggcgtacggc ccatgactgc cgccagatca
    70861 aagcggaaac catcgacgtg gcaggtttct acccaataac gcaggcaggc gctggcataa
    70921 tccaccaccg ccggatgact caaattgagc gtgttgccgc aaccggtcca gttgtgataa
    70981 tcgccgtctt ctcttatcca ataatagcta cggttatcga tcccacgcag cgagaataac
    71041 gggccgtcga ggtccagttc cgcactatgg ttgagcacga tatcaagaat gacttcgata
    71101 cccgctttat gcagtgcttt gattgcatcg cgaaactcat ccagcgccgt ttctggcgag
    71161 caggcatacg ccggatgcag cgcaaacatc gccaccgggt tgtaacccca gtagttactt
    71221 agccccatgc gttgcagacg tggttcactg gcaaactgcg ccactggcag cagttccagc
    71281 gcggtaatgc ccaattgttt caaatagttg atcatcaccg gatgcccgag ggctttataa
    71341 gtgccacgga tctcgaccgg gatctccggg tgcaagtacg ttaatccttt gacatgggct
    71401 tcataaatga tggtgctgcc ccacggcgtg cgcggcgggg catcatcttc ccagtcatag
    71461 tgatcaacca ccactacgca tttcggcgca atggcggcgt tgtcgcgata gtcaggttca
    71521 ttatgaccgg cgtgcagcag cgggttatct ttaaactccc cgtcaatttg ccgcgcgcaa
    71581 ggatcaatca acaacttcgc cgggttaaag cgatgcccct cggcgggttg ccaggggcca
    71641 tgaacgcgat aaccataacg caaacccggg cgcgcatccg gcagataacc gtgccaaatg
    71701 tcgccactgt gccctggcaa gtcatagcga tgttcctggc cattggcgtc aaagacacac
    71761 agttctaccc gctcggcatg agcggagaaa agtgtgaagt tgacgccctg accgtcgtaa
    71821 tgcgcgccga ggggagcggg tttgccaatg gcgagttgtg tcattctgcc tcccgaacca
    71881 gccagatagt ggccagcggt ggtagcgtca ggcttagtga atgctgacga ccgtggctgg
    71941 caatctcatc gctgtgtacc gtgccgccat tgcctgcatt actgccgtga tagtgcatgg
    72001 aatcggtatt gaggatttca cgccatttgc ccggctggtt tatgccgaag cgataatcat
    72061 gacgcggtac cggcgtaaag ttactggcaa cgatgatttc gttaccctct ttatcgcgac
    72121 gcacaaagat cagcaccgag cgttctttgt catccaccac cagccattca aagccgtacg
    72181 ggtcaaaatc cagttcatgc attgctttat ggtggcggta ggtgaggttc agatcgcgca
    72241 ccagacgctg gacaccgtgg tgccagttat cgccgccttc caacagatgc cagtcgaggc
    72301 tggcgtcatg gttccactcg cggccctggg caaattcgtt acccatgaac agtagtttct
    72361 tgcccgggaa tgcccacatc cagccatagt aggcgcgcag gttcgcgaat ttctgccatg
    72421 cgtcgcccgg catgcggtcg agaatcgatt ttttaccgtg gaccacttca tcatgcgaca
    72481 acggcaggac gaagttttca gtgtagttgt agagaatccc gaaggtcagt ttatcgtgat
    72541 gatactgacg ataaaccggg tcgagcttca tgtagtccag ggtgtcatgc atccagccga
    72601 ggttccactt gtaccagaag cccagaccgc ccatatcctg cggacgagaa acgccaggga
    72661 aatcggtaga ctcctcagcc attgtcaccg caccggaaac ctgctcacca agaatacggt
    72721 tggtattacg caagaattca atcgcttcaa gattctcgcg cccgccaaat tcgttcggga
    72781 tccactcccc ctctttacgg ctgtagtcgc gataaatcat tgacgccacc gcatcgacgc
    72841 gcagcgcatc aataccaaaa cgttcaatcc agtaaagcgc gttaccgacg aggaagttac
    72901 tgacttcacg gcgaccatag ttgtagatca gcgtgttcca gtcctgatga tagccttcac
    72961 gcggatcgct gtgttcatac aagttcgtgc catcaaattc ggcaagcgca aagtcatcag
    73021 tcgggaagtg gcctggcacc cagtcgagaa tcacgttcag accagctgcg tgtgcggcat
    73081 caatgaaata acggaagtcg tcgcgagtac caaaacggcg ggttggcgca tacaggccgg
    73141 ttggctgata accccaactg ccatcgaagg gatgctcgtt aatgggcagt agttcgaggt
    73201 gggtaaagcc catccattta gcataaggca ccagttgatc ggccagctcg cggtagctca
    73261 accagaaatt gttgtcggtg tggcgacgcc aggaacccag gtgaacttca taaatagaga
    73321 ttggcgcatc aaactgattc gcttttttgc gctcttcagt ctgtacaacc ttttccggca
    73381 gcccgcaaat aagagacgcg gtttccgggc gcatttgcgc ttcaaaggca taagggtcgg
    73441 acttcagacg caagttgcca ttggcatcaa tcatctcgta tttatagagc tgaccgttat
    73501 gcgccccagg gataaacagt tcccagatgc cgctctcttt acgcaggcgc atcgggtgac
    73561 ggcgaccgtc ccagtagttg aattgcccaa ccaccgagac ccgacgggcg tttggagccc
    73621 agacagagaa acgcgtacct gtgacgccat ccatagtatc tgcatgcgcg cctaaggttt
    73681 catacgggcg caggtgagta ccttcagata atagccaggc atccatttcc tggattagcg
    73741 gaccaaaacg gtaaggatca tcaatcaggt tttgctgacc atgccagaca acagccaact
    73801 gatagcggaa aaaattctta cgtcgcggaa tgacgccgct aaagaatccc cgtgagtcga
    73861 gacactccag ttttgcgagt ttgcgcccgg ttttcggttc aatcacccac acatcggtag
    73921 cgtcgggtaa aagggcacgg acttccagtc ccgcggtggt tttatgcatt cccagtacgg
    73981 aaaaaggatc cgcaaaatgg cctgcaatta gcgcgttaat cacgtctcta tcgatacgat
    74041 cggacatgct tgtcttcctg ttttattgtg tcaccccatc caattggatt tttgacttct
    74101 ggttgtgaca tttttttgac ctgaacggcg cagcactctg tgcatcctct ctgcgtcgtc
    74161 ctcacttcag gtaaggctgt gaatactcat gtattcagcc acccttaaag aatagccaat
    74221 gctctattta actcccggta aatcatgaaa catctgcgct tactcctgta ttacgcacta
    74281 acaggggcgg catcgcgccc cagatttaat gaataaagat tacgccagtt gacgaagcat
    74341 ccgacgcagc ggctccgcgg ccccccacag cagctggtcg cccacggtaa aggctgacag
    74401 gaactctggt cccatattca gcttacgcag gcggcctacc ggcgtggtca gcgtgccggt
    74461 aacggcagct ggggttagct cacgcatagt gatttcccga tcgttcggaa cgactttcgc
    74521 ccacggattg tgcgcagcca gcagttcttc cacggtcgga atagacacat cttttttcaa
    74581 tttaatagtg aatgcctggc tgtggcagcg caatgccccg acacgcacac ataaaccatc
    74641 taccggaatt acggaagatg tgttgaggat cttgttggtt tccgcctgcc ctttccactc
    74701 ttcgcggctc tgaccgttat cgagctgttt gtcgatccac ggaatcaggc tacccgccag
    74761 cggcacgcca aagttatcca ccggcagctc accgctacgg gttaaggttg tgactttgcg
    74821 ttcgatatcg agaatagcag aggacggggt cgcgagttca tctgccacat ggccatacag
    74881 atggcccatc tgggttaata actcacgcat atgtcgcgca ccaccgccgg aagcggcctg
    74941 gtaggttgca acggacaccc aatcaacaag atcattggcg aataaaccac ccaacgacat
    75001 caacatcagg cttacggtac agttaccgcc aacaaaagtc ctgatgccat tatttaatcc
    75061 gtcggtaatg acgtcctgat tgacggggtc aagaatgatg atggcgtcat ctttcatgcg
    75121 cagagacgat gctgcgtcaa tccagtaacc ttgccatccg ctttcacgaa gctttggata
    75181 gatttcgttg gtataatcgc cgccctgaca ggtcacaatg atatcgaggg cctttagcgc
    75241 ctccagatca aaggcatcct gaagtgtgcc agtggttccg ccaaaagacg gcgcagcctg
    75301 gccaagctga gaagtagaaa agaagacagg gcgaatggcg tcgaagtcgc gctcttcaac
    75361 catgcgttgc atgagaacgg agccgaccat accgcgccag ccgataaaac caacattttt
    75421 cataagcgtt tttttcctgc aaagatgtgt gctgtataaa tgtgccggtc tcctcttggc
    75481 acatctttca ccatacaaaa agcagccaaa gtcgcaagtg aaattaatca atgatagcga
    75541 agccatcagt aatgcgactt atcctgcttt gttagcacgc agaaagtccg cggcaattat
    75601 cagggaattt gagttatgaa tgaaatcatt tctgcagcag ttttattgat cctgattatg
    75661 gatccgctcg gaaacctacc tattttcatg tccgtactga aacatactga accgaaaaga
    75721 cggcgggcaa tcatggtgcg agagttgctt attgctctcc tggtgatgct ggtgttcctg
    75781 tttgcgggtg agaaaattct ggcatttctt agcctacgag cagaaaccgt ctccatttct
    75841 ggcggcatca ttctgtttct gatcgccatt aaaatgattt tccccagcgc ttcaggaaat
    75901 agcagcgggc ttccggcagg tgaagagcca tttatcgtgc cgttggcaat tccgttagtc
    75961 gccgggccga ctattctcgc cacgctgatg ttgttgtctc atcagtaccc gaatcagatg
    76021 gggcatctgg tgattgctct gctgctggcc tggggcggca cctttgtcat cctgctacag
    76081 tcttcgctat ttttacgtct gctgggcgag aaaggggtga acgcacttga acgcctgatg
    76141 ggattgattc tggtgatgat ggcaacccag atgttcctcg acggcattcg aatgtggatg
    76201 aaggggtaac gaggagagtt tttcgaaaag aacccggtag cgtcacaact accgggcgaa
    76261 caaacttaac tcaacagctg gaacgcaatc atcccaacga tggcaccgac agtgccgagg
    76321 atggtttcca tcatggtcca ggttttcagc gtttcggctt cggtcgcgcc ggtaaattta
    76381 ccgaacaacc agaaaccggc gtcgttaacg tggctgacaa caatcgaacc accagcgata
    76441 caaatcgaca gcgccgccat ttgcgcaccg gagtagttca gttgttcaat aaccggcatc
    76501 accagtccta ccgccgttaa acaggctacg gtggcagaac cctgaatgat gcgcactgca
    76561 gctgccagca cgaagcaggt gatagcaatc ggcaggccca tgccggttaa cgcttcgccc
    76621 agtgccggac ctacgccaga gtcaaccagc acctgtttga acacgccgcc cgcaccaatc
    76681 accagcagaa tgatccccgc cggttgcagc gcgtgaccgc aaatctccat cactttgtct
    76741 tttggcatgc cctgacgcat tgccagaccg taaatcgcca ccagacaagc aaccagaatc
    76801 gcggtaaacg gatgaccgat aaactcaaac cattcgtaag cagttgatcc ttccggcaca
    76861 aaacgcgcgg caatggtttt cagccctacc agcaccagcg gcagcaggat cagcgacagg
    76921 ctgaatccga aagatggcat tttgccttcg ccgagatgcg gttcgctgat gtcgtcagga
    76981 atatgcagct caacgtaacg gctgatgaag ttaccccaca gcggcccggc aataatcatt
    77041 cccggaattg ccgcacacag gccaatcagg atcatccagc caaagtcggc attcatctgc
    77101 gatgccagca gcatcggcgc tggtccaggc accagaaatg ccgccgctgc cgccacgcct
    77161 gcaaataatg ggattaccag cttcaccagg ttcgtaccgg tgtggcgcgc cattgagaaa
    77221 gcaacgctaa tcagcagaac tatcgccact tcaaagaaca gcggtagcgc acagaccagc
    77281 cccgcaaggc cgatggcata atgcgcgcgg ctgtgaccga aggatttgag cattttgacg
    77341 gcaatctgat cgactgcgcc ggtttcatgt aagatcttgc caaacatagc tcccagggcg
    77401 acaaccaccg ccaggaagcc gagggtgcct cccatccctt tttccatcgt cgctgcgatt
    77461 ttatcgagcg gcataccaga aaaaaggcca gcccccatgg acaccaccat taaagccagg
    77521 aaagcgtgca tacgcgcctt catgactaaa aacagcagca gtaaaacaga ccctactgct
    77581 gttaaaacaa gcgttaatgt agtcactact tatttgcctt ttttaataac ctcaatggtg
    77641 cttgccacaa caccttccag cggttgatcg atatccacca ccagtacatc ggtttcgtcc
    77701 gcacccggct cctgcagcgt ttcaaactgc gtcaccaaca tttgggtttt aaagaaatgg
    77761 cctttgcgcg ctttcaggcg gctttcaatc acatcaaaat cgcctttcaa atagatgaaa
    77821 gagagattcg gattaccttc acgcagcaag tcgcgatagt gttttttcaa tgcagaacag
    77881 acgatcagcg acactttatt agtgcgctgc atagcaaacg cggcgtcgtt cagcgcctgc
    77941 aaccacggtt tgcgatcgtc gtcattcagt ggttcgccag acgccatttt ttcgatattg
    78001 cgccgtggat ggaggaaatc gccatcaaga aacgcggcat gaagttgatg cgccacttca
    78061 ctggcgaccg cagatttgcc gctgcccgat acgcccatca agacgtaaat gtggtgatca
    78121 tggttagtcg tgctcaaagt ggtgccccca caatacaaga attaaaaatg ttacgggtaa
    78181 ctgttatcgg taacattgtc cagccggaca atatcagaag caatatccat ccatgcctta
    78241 agtgtataag tgtgagctac ttcaaatttg tgggcttaaa tagatccgcc cggtgacaag
    78301 gtgaaaccta aatctaacat tttcggtgtc acagattcgc cacgaatacg cgccagcagg
    78361 cgttcagcgc caatactgcc catccgctca cgcggcgtca gcacgctcgc aagtcgtggc
    78421 tccatcacct gaccaatgtc atgaccgtgg aaaccggcaa tcgccatatc gtcaggaact
    78481 tttaacccca gacgctgaca ttcaaacgcc gcgccgaccg ccaggtcatc attcgtacag
    78541 aacacgccat ccagctgcgg atattcccgc cgcgcctggc gaatcagttc aataccggaa
    78601 gagtaagaag aagattgctc aaccatcacg ctatatggca ccaggcctgc atccagcatc
    78661 gcctgttcgt atcccttctg tttgatgata gtacgttcgt cgagacgtgc gccgagatag
    78721 gcaatgtggc gatgcccgcg agcaataatg gcagtggtca tctggcgtgc tgcttcaaag
    78781 ttatcaaaac cgacggcgat atcaaggcat ggcgacttgc tgtccatcag ttccaccacg
    78841 ggaatacccg ccacttcaat catctttaag gtgcgcggcg tgtgggtacg ttcggtgagg
    78901 atcaggccgt cgatattcca ggagagcatg gattcgaggc gttcttgctc catttccggt
    78961 ttataaccgt agtgcgccag catggtctga taaccgtgcg cgtcggtgac gctttcgatt
    79021 ccgcgtaata cttccgcgaa aacctggttg gtgagagaag gtaacaggac gccaatcgcc
    79081 cggctggtgg cgttagagag gatatcgggc gcacgattgg gaatatagcc cagttcatca
    79141 agagccgcgg caatcttgcc gcgtagagcg acggaaacct gctccgggtt gcgtaaaaaa
    79201 cggctgaccg tcattttggt cacgcctaca cggtcagcca catcctgaag tacgggtctt
    79261 ttctttttca tcgtcctgaa ggtacaaaag agatagattc tcttagttta acacggacac
    79321 atcagaacct tcccggggaa aacagtgctt gtttacaatt attagatata cactaaatca
    79381 attgcatcgc attgtgctaa cgacgcggca aaaccccgga agcgtacatc agcacgcgac
    79441 cggagcgagc gaggaagcct gcaaaaaggc aggcttcaaa gatgccgttg agttttaaac
    79501 cggcggcaga tcgaacagta acacttcgct gtcgctatcc gcatggatgg agattgcctg
    79561 ctcatcccag attgccagac catcgctggt cgaggctttc acgccgttaa tggtgacatt
    79621 gcctttcacc acctggatcc agacgcggcg ttcagcggca atctgatgca ccgactgctc
    79681 atctttcagc aacgcccagc ggtacagttc catatcctga tgcactttca atgaaccatc
    79741 tcgcgcatcc ggcgagagca ccagctgttt gccctgtacg gcatcgaagc gacgctgttc
    79801 ataacgcggc gtaataccgt tttcttcagg catgatccag atctgataca gatgcagacg
    79861 ctcggtgctg cttgggttgt actctgagtg acgaataccc gtaccagcac tcataatctg
    79921 gaactcaccc gccggaacct gctctttatt gcccatgctg tcctgatgct caacagtacc
    79981 ttccagcacg taggtcaaaa tttccatatc tttatgcggg tgagtgccga agccctgccc
    80041 tgcttcaatc acgtcgtcgt taatcacgcg cagcgcggag aagcccataa agttcggatc
    80101 gtaatagttg gcaaaagaga aagtatgcca ggagtccagc cagccatgat ttgcatgacc
    80161 acgttcattt gctttgcgta agtagatcat ttgtattcgc cccctgaatg atttcgatgg
    80221 gcttagtgtg gacccgatct gcctgggatg atagagggtg aaaattgacc cctctgttca
    80281 aaaaaattga actattcgag gggccatcaa acttacttag cgagagttac tgtggaggga
    80341 gaggcttgct caaatccgcg ttcaaggatt tccagattgg taagaacttc agattccttg
    80401 acgtaatttg gcgcaccgtg ggtgatggtt tgatacaacg catcataaac gcgcccgtaa
    80461 tcgcccatct ccggcttcat ctcttctctg accgtcacgc cctcgtcatt gacatactcc
    80521 agcacaccga ccgaatcatc cgctgcgaat cccggttcgc ccggcataat attagccttc
    80581 aggctggttt cctgctggtc gataccgtat ttaataaacg aacctttctt accgtgaacg
    80641 ataaatttcg gataatcgat tttcaccaga tggctggttt tgacgatggc tttcaggtcg
    80701 ccataaaaca gttgcgcttc aaaggtgtcg tcaggattgg ctttattacg caggctgcgg
    80761 atgtcataag cgacgtgatc cgggcgaccg aacagagaaa taatctggtc catcgtatgc
    80821 acaccaaggc cataaaacgc gccatcctgc ggcagcccag gtttggtttc tgccaccggg
    80881 cggtaatagt caaaatggct ttccacttca acaatctctc ccaacttgcc actttcaatc
    80941 gcttttttcg ctgtcaggaa gcaggagtca aagcgacgat tctgatacgg cgtgacggtc
    81001 agccctttgc ttttcgccaa cgcaaacagc tctttcgcct gcgcaagtgt cggagtgaac
    81061 ggtttttcga ccagcacatt tttcccggct tccagcgcgc gtttcgcgta ctcgaaatgg
    81121 ctgtccgcgt gggtgcagac aacaaccagc ttaacatcgg gatcgtttag tacttcgtcg
    81181 agatcgctgg tgaaatggat atgggaataa atgggagcct gttcttccgg cttcgcatgg
    81241 cgacgaaaaa tatgcgcgac atgccagcta tccttgcggt taagtacata cggcagatgg
    81301 taacgggtgg tgcttttgcc gaagccaata aaggcgcagt tgatgaccat gatttcgtcc
    81361 tttttaaggt ggttatttac accttagcgc aaagcggacg tggttcctac tggagtgcgc
    81421 ataacgaaca caagcactcc cgtggataaa ttgagaacga aagatcaaaa aaaaagccag
    81481 cacccggctg gctaagtaat actggaagca atgtgagcaa tgtcgtgctt tcaggttctc
    81541 cgcgagggtc ttcctgatcg cgagacaata ataatcattc tcattcgcac ttgtccaaca
    81601 ctttttgcaa aaaaatgcat ttgactcgca tttgaaagtc aatgatgttg aaagggacat
    81661 ttaccccaaa gaggacaaag gaatgagtga gatagtaata cgccacgcag aaacacggga
    81721 ttacgaggcc atcaggcaga ttcacgccca gccggaggtg tattgcaaca cactacaggt
    81781 gtctcatcct tccgatcata tgtggcagga gcgactcgcc gatcgtcccg gcatcaagca
    81841 actcgtcgcc tgtattgatg gagacgtcgt gggccatctc accattgacg tgcaacagcg
    81901 cccacgccgc agtcatgttg ccgattttgg tatctgtgtc gactctcgtt ggaagaaccg
    81961 cggcgtcgcc agcgccctga tgcgagagat gattgaaatg tgcgacaact ggttgcgggt
    82021 agatcgcatt gaactaaccg tgtttgtcga taacgccccg gcaattaagg tctataaaaa
    82081 atacggcttt gaaattgaag ggactggtaa gaagtacgca ttgcgtaatg gtgaatatgt
    82141 cgatgcatat tatatggcgc gggtgaagta agatagtgcc ctttttctga gatggaaaaa
    82201 gggtgtcatt caaaatcgac ataccttcct tt
//
LOCUS       DAPHKZ010000004        81089 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.004, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000004 DAPHKZ010000000
VERSION     DAPHKZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 81089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81089
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.004"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            151..594
                     /gene="cmtB"
                     /locus_tag="RH288_000230"
     CDS             151..594
                     /gene="cmtB"
                     /locus_tag="RH288_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIA"
                     /protein_id="HDV4029335.1"
                     /translation="MRLSDYFPESSISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQ
                     AIKDSTINNGPYYILAPGVAMPHARPECGALKTGMSLTLLEQGVYFPGNDEPIKLLIG
                     LSAADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISRG"
     gene            622..2010
                     /gene="cmtA"
                     /locus_tag="RH288_000231"
     CDS             622..2010
                     /gene="cmtA"
                     /locus_tag="RH288_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDV4029336.1"
                     /translation="MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWL
                     PNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSM
                     IMGPLGGLVIKYVDKALEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANT
                     FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMV
                     ASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIA
                     GGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLI
                     LKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFR
                     KRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLD
                     TLFNQLTAEHKH"
     gene            2025..3302
                     /locus_tag="RH288_000232"
     CDS             2025..3302
                     /locus_tag="RH288_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDV4029337.1"
                     /translation="MKTKVAAIYGKRDVRLRVFELPEITDNELLVSVISDSVCLSTWK
                     AALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSG
                     YSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
                     TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQV
                     QKLLPVELAASKGIELVYVNTKGMSDPVQMLRALTGDAGFDDIFVYAAVPAVVEMADE
                     LLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQL
                     QPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKE
                     LARLVEETHGIWNEQAEKYLLAQFGVDIGEAAQ"
     gene            3299..4264
                     /gene="yggF"
                     /locus_tag="RH288_000233"
     CDS             3299..4264
                     /gene="yggF"
                     /locus_tag="RH288_000233"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HDV4029338.1"
                     /translation="MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALN
                     DVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAV
                     MAFAPRDSLLHAPDMYMKKLVVNRLAAGAIDLSLPLTDNLRNVAKALGKPLDKLRMVT
                     LDKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISAC
                     AVKALGGDMQAELIDFCQAKGDYTENRQIAEQERKRCKAMGVDVNRVYSLDELVRGND
                     ILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLH"
     gene            4286..4795
                     /gene="fumE"
                     /locus_tag="RH288_000234"
     CDS             4286..4795
                     /gene="fumE"
                     /locus_tag="RH288_000234"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarase E"
                     /protein_id="HDV4029339.1"
                     /translation="MATLTEDDVLEQLDAQDNLFSFMKTAHTILLQGIRQFLPSLFVD
                     NDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQD
                     ETPGFADDMTWDFISNVNSITRNAMLYDALKAMKFADFSVWSEARFSGMVKTALTLAV
                     TTTLKELTP"
     gene            4792..5505
                     /locus_tag="RH288_000235"
     CDS             4792..5505
                     /locus_tag="RH288_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="HDV4029340.1"
                     /translation="MKIELTVNGLKIQAQYQNEEIENVHKPLLHMLAALQTVNPQRRT
                     VVFLCAPPGTGKSTLTTFWEYLAQQDPELPAIQTLPMDGFHHYNSWLDAHQLRPFKGA
                     PETFDVAKLTENLRQVVEGDCTWPQYDRQKHDPVEDALHVTAPLVIVEGNWLLLDDEK
                     WLELASFCDFSIFIHAPAQILRERLISRKIAGGLTRQVAEAFYARTDGPNVERVLMNS
                     RQANLIVEMTEEGRYHFTS"
     gene            5790..6809
                     /gene="epd"
                     /locus_tag="RH288_000236"
     CDS             5790..6809
                     /gene="epd"
                     /locus_tag="RH288_000236"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HDV4029341.1"
                     /translation="MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV
                     YGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAG
                     ITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIV
                     DYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     TVAFR"
     gene            6859..8022
                     /gene="pgk"
                     /locus_tag="RH288_000237"
     CDS             6859..8022
                     /gene="pgk"
                     /locus_tag="RH288_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDV4029342.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVND
                     VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            8237..9316
                     /gene="fbaA"
                     /locus_tag="RH288_000238"
     CDS             8237..9316
                     /gene="fbaA"
                     /locus_tag="RH288_000238"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HDV4029343.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
                     YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFQELNAIDVL"
     gene            9674..10534
                     /gene="mscS"
                     /locus_tag="RH288_000239"
     CDS             9674..10534
                     /gene="mscS"
                     /locus_tag="RH288_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HDV4029344.1"
                     /translation="MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLII
                     ARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
                     KIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKD
                     REMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKEDKAA"
     gene            10673..11308
                     /gene="argO"
                     /locus_tag="RH288_000240"
     CDS             10673..11308
                     /gene="argO"
                     /locus_tag="RH288_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HDV4029345.1"
                     /translation="MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCA
                     ISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAE
                     VMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
                     FGLALLAAWLAPRLRTAKAQRIINLVVGCVMWFIALQLARDGIAHAQALFS"
     gene            11401..12141
                     /locus_tag="RH288_000241"
     CDS             11401..12141
                     /locus_tag="RH288_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HDV4029346.1"
                     /translation="MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQA
                     AIQFDDQVDVVFQLEPVDQQPAKTPAAQ"
     gene            12308..13204
                     /locus_tag="RH288_000242"
     CDS             12308..13204
                     /locus_tag="RH288_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417396.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4029347.1"
                     /translation="MDIFISKKMRNFILLAQTNNIARAAEKIHMTASPFGKSIAALEE
                     QIGYTLFTRKDNNISLNKAGQELYQKLFPVYQRLSAIDNEIHNSGRRSREIVIGIDNT
                     YPTIIFDQLISLGDKYEGVTAQPVEFSENGVIDNLFDRQLDFIISPQHVSARVQELEN
                     LTISELPPLRLGFLVSRRYEERQEQELLQELPWLQMRFQNRANFEAMIDANMRPCGIN
                     PTIIYRPYSFMAKISAVERGHFLTVIPHFAWRLVNPATLKYFDAPHRPMYMQEYLYSI
                     RNHRYTATMLQHIAEDRDGTSH"
     gene            complement(13201..14679)
                     /gene="scpC"
                     /locus_tag="RH288_000243"
     CDS             complement(13201..14679)
                     /gene="scpC"
                     /locus_tag="RH288_000243"
                     /EC_number="2.8.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionyl-CoA:succinate CoA transferase"
                     /protein_id="HDV4029348.1"
                     /translation="METQWTRMTANEAAEIIQHNDMVAFSGFTPAGSPKALPTAIARR
                     ANEQHEAKKPYQIRLLTGASISAAADDVLSDADAVSWRAPYQTSSGLRKKINQGAVSF
                     VDLHLSEVAQMVNYGFFGDIDVAVIEASALAPDGRVWLTSGIGNAPTWLLRAKKVIIE
                     LNHYHDPRVAELADIVIPGAPPRRNSVSIFHAMDRVGTRYVQIDPKKIVAVVETNLPD
                     AGNMLDKQNPMCQQIADNVVTFLLQEMAHGRIPPEFLPLQSGVGNINNAVMARLGENP
                     VIPPFMMYSEVLQESVVHLLETGKISGASASSLTISADSLRKIYDNMDYFASRIVLRP
                     QEISNNPEIIRRLGVIALNVGLEFDIYGHANSTHVAGVDLMNGIGGSGDFERNAYLSI
                     FMAPSIAKEGKISTVVPMCSHVDHSEHSVKVIITEQGIADLRGLSPLQRARTIIDNCA
                     HPMYRDYLHRYLENAPGGHIHHDLSHVFDLHRNLIATGSMLG"
     gene            complement(14703..15488)
                     /gene="scpB"
                     /locus_tag="RH288_000244"
     CDS             complement(14703..15488)
                     /gene="scpB"
                     /locus_tag="RH288_000244"
                     /EC_number="7.2.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA decarboxylase"
                     /protein_id="HDV4029349.1"
                     /translation="MSYQYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLN
                     RPEIRCIILRAPSGSKVFSAGHDIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISM
                     VEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKEL
                     IFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGE
                     AHTMNSDEFERIQGMRRAVYDSEDYQEGMNAFLEKRKPNFVGH"
     gene            complement(15499..16494)
                     /gene="meaB"
                     /locus_tag="RH288_000245"
     CDS             complement(15499..16494)
                     /gene="meaB"
                     /locus_tag="RH288_000245"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HDV4029350.1"
                     /translation="MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLL
                     DAIMPYCGNTLRLGVTGTPGAGKSTFLEAFGMLLIREGLKVAVIAVDPSSPVTGGSIL
                     GDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
                     ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLIVINKDDGDNHTNVAIARHMYE
                     SALHILRRKYDEWQPRVLTCSALEKRGIDEIWHAIIDFKTALTASGRLQQVRQQQSVE
                     WLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQLSEFIQTQYFD"
     gene            complement(16487..18631)
                     /gene="scpA"
                     /locus_tag="RH288_000246"
     CDS             complement(16487..18631)
                     /gene="scpA"
                     /locus_tag="RH288_000246"
                     /EC_number="5.4.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HDV4029351.1"
                     /translation="MSNVQEWQQLANKELSRREKTVDSLVHQTAEGIAIKPLYTEADL
                     DNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAGFSTAKESNAFYRRNLAAGQKGL
                     SVAFDLATHRGYDSDNPRVAGDVGKAGVAIDTVEDMKVLFDQIPLDKMSVSMTMNGAV
                     LPVLAFYIVAAEEQGVTPDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCS
                     GNMPRFNTISISGYHMGEAGANCVQQVAFTLADGIEYIKAAISAGLKIDDFAPRLSFF
                     FGIGMDLFMNVAMLRAARYLWSEAVSGFGAQDPKSLALRTHCQTSGWSLTEQDPYNNV
                     IRTTIEALAATLGGTQSLHTNAFDEALGLPTDFSARIARNTQIIIQEESELCRTVDPL
                     AGSYYIESLTDQIVKQARAIIQQIDEAGGMAKAIEAGLPKRMIEEASAREQSLIDQGK
                     RVIVGVNKYKLDHEDETDVLEIDNVMVRNEQIASLERIRATRDDAAVTAALNALTHAA
                     QHNENLLAAAVNAARVRATLGEISDALEVAFDRYLVPSQCVTGVIAQSYHQSEKSASE
                     FDAIVAQTEQFLADNGRRPRILIAKMGQDGHDRGAKVIASAYSDLGFDVDLSPMFSTP
                     EEIARLAVENDVHVVGASSLAAGHKTLIPELVEALKKWGREDICVVAGGVIPPQDYAF
                     LQERGVAAIYGPGTPMLDSVRDVLNLISQHHD"
     gene            complement(18835..19728)
                     /gene="argP"
                     /locus_tag="RH288_000247"
     CDS             complement(18835..19728)
                     /gene="argP"
                     /locus_tag="RH288_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HDV4029352.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPES
                     RMMRKVTDALLDYGHKVLRQD"
     gene            19870..20099
                     /locus_tag="RH288_000248"
                     /pseudo
     CDS             19870..20099
                     /locus_tag="RH288_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            20155..20814
                     /gene="rpiA"
                     /locus_tag="RH288_000249"
     CDS             20155..20814
                     /gene="rpiA"
                     /locus_tag="RH288_000249"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDV4029353.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
                     VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            21070..22302
                     /gene="serA"
                     /locus_tag="RH288_000250"
     CDS             21070..22302
                     /gene="serA"
                     /locus_tag="RH288_000250"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDV4029354.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDD
                     EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK
                     NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK
                     ALQAMKAIPGTIRARLLY"
     gene            22531..22590
                     /gene="ibsC"
                     /locus_tag="RH288_000251"
     CDS             22531..22590
                     /gene="ibsC"
                     /locus_tag="RH288_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsC"
                     /protein_id="HDV4029355.1"
                     /translation="MMRLVIILIVLLLISFSAY"
     gene            complement(22691..23293)
                     /locus_tag="RH288_000252"
     CDS             complement(22691..23293)
                     /locus_tag="RH288_000252"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDV4029356.1"
                     /translation="MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMM
                     TYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQ
                     SELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
                     HYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW"
     gene            complement(23314..23497)
                     /gene="ssrS"
                     /locus_tag="RH288_000253"
     ncRNA           complement(23314..23497)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RH288_000253"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(23539..23868)
                     /gene="zapA"
                     /locus_tag="RH288_000254"
     CDS             complement(23539..23868)
                     /gene="zapA"
                     /locus_tag="RH288_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDV4029357.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKER
                     TRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITE
                     KTNQNFE"
     gene            24036..24614
                     /gene="ygfB"
                     /locus_tag="RH288_000255"
     CDS             24036..24614
                     /gene="ygfB"
                     /locus_tag="RH288_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YgfB"
                     /protein_id="HDV4029358.1"
                     /translation="MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDS
                     SWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH"
     gene            24640..25965
                     /gene="pepP"
                     /locus_tag="RH288_000256"
     CDS             24640..25965
                     /gene="pepP"
                     /locus_tag="RH288_000256"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HDV4029359.1"
                     /translation="MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPY
                     RQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEK
                     LGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAP
                     ATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHH
                     EFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRT
                     FPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKG
                     DVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPD
                     AEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ"
     gene            25962..27140
                     /gene="ubiH"
                     /locus_tag="RH288_000257"
                     /gene_synonym="visB"
     CDS             25962..27140
                     /gene="ubiH"
                     /locus_tag="RH288_000257"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HDV4029360.1"
                     /translation="MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPG
                     FDGRAIALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLAAL
                     GQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLESGETLTGRVLVA
                     ADGTHSALATACGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQHGPLAMLPMSDG
                     RCSLVWCHPLERREEVLSWSDEKFCRELQSTFGWRLGKITHAGKRSAYPLALTHAARS
                     ITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAQERGEDMGDYGVLCRYQQ
                     RRQSDREATIGVTDSLVHLFANRWAPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
                     "
     gene            27163..28365
                     /gene="ubiI"
                     /locus_tag="RH288_000258"
                     /gene_synonym="visC"
     CDS             27163..28365
                     /gene="ubiI"
                     /locus_tag="RH288_000258"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HDV4029361.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVQEPLAANA
                     PPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYS
                     HLGHIVENSVIHYALWNKAHQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
                     IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPEEAQRMQQASEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYA
                     RQFASHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRR
                     YERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL
                     NDLPEWLR"
     gene            complement(28439..28522)
                     /locus_tag="RH288_000259"
     CDS             complement(28439..28522)
                     /locus_tag="RH288_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029362.1"
                     /translation="MSKNTKSKNNGIRKYNAKTEVKLVYFK"
     gene            28813..29907
                     /gene="gcvT"
                     /locus_tag="RH288_000260"
     CDS             28813..29907
                     /gene="gcvT"
                     /locus_tag="RH288_000260"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HDV4029363.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDA
                     GMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKALSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
                     NDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREH
                     GTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            29931..30320
                     /gene="gcvH"
                     /locus_tag="RH288_000261"
     CDS             29931..30320
                     /gene="gcvH"
                     /locus_tag="RH288_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDV4029364.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            30439..33312
                     /gene="gcvP"
                     /locus_tag="RH288_000262"
     CDS             30439..33312
                     /gene="gcvP"
                     /locus_tag="RH288_000262"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HDV4029365.1"
                     /translation="MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQ
                     IVPKDIQIATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQ
                     QVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAGVLTRAEAAEINLRSDILNAVGITLDETTTRENVMQLFNVLLGDNHGLDID
                     TLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQD
                     AFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ"
     gene            33579..34322
                     /locus_tag="RH288_000263"
     CDS             33579..34322
                     /locus_tag="RH288_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV4029366.1"
                     /translation="MAIALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMN
                     LITQAGGKAFVLQADISDENQVVAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAE
                     RINRVLSTNVTGYFLCCREAVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASK
                     GAIDTLTTGLSLEVAAQGIRVNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQA
                     EEVAQAIVWLLSDKASYVTGSFIDLAGGK"
     gene            complement(34379..35812)
                     /gene="bglA"
                     /locus_tag="RH288_000264"
     CDS             complement(34379..35812)
                     /gene="bglA"
                     /locus_tag="RH288_000264"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HDV4029367.1"
                     /translation="MKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHG
                     VPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEA
                     QPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASALAVKAARRINPEMKVGCMLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYALCELYERYQRPLFIVENGFGAYDKVEEDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDD
                     GTGDMSRSRKKSFNWYKEVIASNGEKL"
     gene            35857..36168
                     /locus_tag="RH288_000265"
     CDS             35857..36168
                     /locus_tag="RH288_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDV4029368.1"
                     /translation="MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRF
                     EDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTELKKVIADIYPGQTQFYVIEFKC
                     L"
     gene            36332..36991
                     /locus_tag="RH288_000266"
     CDS             36332..36991
                     /locus_tag="RH288_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDV4029369.1"
                     /translation="MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDL
                     NASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
                     VKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQ
                     A"
     gene            complement(37187..38167)
                     /gene="ygfZ"
                     /locus_tag="RH288_000267"
     CDS             complement(37187..38167)
                     /gene="ygfZ"
                     /locus_tag="RH288_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HDV4029370.1"
                     /translation="MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQ
                     VTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYA
                     VFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAER
                     FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRT
                     GTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE"
     gene            38410..38676
                     /gene="sdhE"
                     /locus_tag="RH288_000268"
     CDS             38410..38676
                     /gene="sdhE"
                     /locus_tag="RH288_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HDV4029371.1"
                     /translation="MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFI
                     RLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI"
     gene            38657..39064
                     /locus_tag="RH288_000269"
     CDS             38657..39064
                     /locus_tag="RH288_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin CptA"
                     /protein_id="HDV4029372.1"
                     /translation="MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLMPWPLSYTPLWMV
                     LLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQEWSIVKAPWMIKSGMMLRLRSD
                     GGKRQHLWLAADSMDEAEWRDLRRILLQQETQR"
     gene            complement(39104..39625)
                     /gene="fldB"
                     /locus_tag="RH288_000270"
     CDS             complement(39104..39625)
                     /gene="fldB"
                     /locus_tag="RH288_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HDV4029373.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLME
                     QYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALG
                     MLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSW
                     CEQILNEMAEHYA"
     gene            39737..40633
                     /gene="xerD"
                     /locus_tag="RH288_000271"
     CDS             39737..40633
                     /gene="xerD"
                     /locus_tag="RH288_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDV4029374.1"
                     /translation="MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRG
                     LTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            40658..41368
                     /gene="dsbC"
                     /locus_tag="RH288_000272"
     CDS             40658..41368
                     /gene="dsbC"
                     /locus_tag="RH288_000272"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HDV4029375.1"
                     /translation="MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPV
                     AGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYK
                     APQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIW
                     CAKDKNKAFDDVMAGKSVAPASCDVDIADHYVLGVQLGVSGTPAVVLSNGTLVPGYQP
                     PKEMKEFLDEHQKMTSGK"
     gene            41374..43107
                     /gene="recJ"
                     /locus_tag="RH288_000273"
     CDS             41374..43107
                     /gene="recJ"
                     /locus_tag="RH288_000273"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDV4029376.1"
                     /translation="MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERS
                     VKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDFDADGATSTALSVLAMRSLGCSN
                     IDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVEHARSLGIPVIVTD
                     HHLPGETLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIA
                     IPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDAQ
                     KLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQ
                     GMQVEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPGMILKFGGHAMAAGLSLEEDKFELFQQRFG
                     ELVTEWLDPSLLQGEVVSDGPLSPAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRS
                     LQIIIDNIWPI"
     gene            43198..44296
                     /gene="prfB"
                     /locus_tag="RH288_000274"
     CDS             join(43198..43272,43274..44296)
                     /gene="prfB"
                     /locus_tag="RH288_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDV4029377.1"
                     /translation="MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAE
                     LDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRG
                     FKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            44306..45823
                     /gene="lysS"
                     /locus_tag="RH288_000275"
     CDS             44306..45823
                     /gene="lysS"
                     /locus_tag="RH288_000275"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDV4029378.1"
                     /translation="MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDH
                     TSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGA
                     AARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(45866..46414)
                     /gene="idi"
                     /locus_tag="RH288_000276"
     CDS             complement(45866..46414)
                     /gene="idi"
                     /locus_tag="RH288_000276"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDV4029379.1"
                     /translation="MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKG
                     QLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDF
                     RYRATDPNGIVENEVCPVFAARTNSALQINDDEVMDYQWCDLADVLHGIDATPWAFSP
                     WMVMQAANSEARKLLSAFAQHN"
     gene            46469..46540
                     /locus_tag="RH288_000277"
     CDS             46469..46540
                     /locus_tag="RH288_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029380.1"
                     /translation="MINQVSVYRQPPVLSGCRQVKTI"
     gene            complement(46537..46662)
                     /locus_tag="RH288_000278"
     CDS             complement(46537..46662)
                     /locus_tag="RH288_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029381.1"
                     /translation="MNFLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF"
     gene            complement(46664..48112)
                     /gene="uacT"
                     /locus_tag="RH288_000279"
     CDS             complement(46664..48112)
                     /gene="uacT"
                     /locus_tag="RH288_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urate/proton symporter UacT"
                     /protein_id="HDV4029382.1"
                     /translation="MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAG
                     AVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFA
                     AVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGL
                     SIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILFITRYAKGFMSNVAVLLGIVFG
                     FLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFL
                     ALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVC
                     ISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYN
                     LYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHAD
                     LVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE"
     gene            48548..50467
                     /gene="ygfT"
                     /locus_tag="RH288_000280"
     CDS             48548..50467
                     /gene="ygfT"
                     /locus_tag="RH288_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     YgfT"
                     /protein_id="HDV4029383.1"
                     /translation="MNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHV
                     VGKGQAANPVACHHCNNAPCVTACPVNALTFQSDSVQLDEQKCIGCKRCAIACPFGVV
                     EMVDTIAQKCDLCNQRSSGTQACIEVCPTQALRLMDDKGLQQIKVARQRKTAAGKASS
                     DAQPSRSAALLPVNSRKGADKISASERKTHFGEIYCGLDPQQATYESDRCVYCAEKAN
                     CNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKD
                     HSGAVSIGNLERYITDTALAMGWRPDVSKVVPRSEKVAVIGAGPAGLGCADILARAGV
                     QVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDITFSDL
                     TSEYDAVFIGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESEEYPLTDVE
                     GKRVVVLGGGDTTMDCLRTSIRLNAASVTCAYRRDEVSMPGSRKEVVNAREEGVEFQF
                     NVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQ
                     AHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGR
                     QAARDMLTLFDTKAS"
     gene            50467..50955
                     /locus_tag="RH288_000281"
     CDS             50467..50955
                     /locus_tag="RH288_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417362.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDV4029384.1"
                     /translation="MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADVFLPRLKVQ
                     RLDSISAPVMCHQCENAPCVGACPVGALTMGEQVVQTNSARCIGCQSCVSACPFGMIT
                     IQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASGEN
                     PL"
     gene            complement(50991..52358)
                     /gene="ghxQ"
                     /locus_tag="RH288_000282"
                     /gene_synonym="ygfQ"
     CDS             complement(50991..52358)
                     /gene="ghxQ"
                     /locus_tag="RH288_000282"
                     /gene_synonym="ygfQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxQ"
                     /protein_id="HDV4029385.1"
                     /translation="MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLA
                     MVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTA
                     FSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
                     LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIA
                     ISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVF
                     DATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTA
                     AGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFI
                     DAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYA
                     GGWAI"
     gene            complement(52394..53710)
                     /gene="guaD"
                     /locus_tag="RH288_000283"
     CDS             complement(52394..53710)
                     /gene="guaD"
                     /locus_tag="RH288_000283"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HDV4029386.1"
                     /translation="MSGEHTLKAVRGSFIDVTRTIDNPEEIASALRFIEDGLLLIKQG
                     KVEWFGEWENGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLN
                     KHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
                     RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQM
                     AMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHC
                     VHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFN
                     MLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEP
                     TATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN"
     gene            complement(53728..55128)
                     /gene="xanQ"
                     /locus_tag="RH288_000284"
     CDS             complement(53728..55128)
                     /gene="xanQ"
                     /locus_tag="RH288_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanQ"
                     /protein_id="HDV4029387.1"
                     /translation="MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPAL
                     IVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIA
                     LGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
                     SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGL
                     CVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGD
                     ITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGV
                     ASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGL
                     KRRETLIVATSLGLGLGVSYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGY
                     RQENVLPGITSAEEMD"
     gene            complement(55293..58163)
                     /locus_tag="RH288_000285"
     CDS             complement(55293..58163)
                     /locus_tag="RH288_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     Mo/Fe-S-binding subunit"
                     /protein_id="HDV4029388.1"
                     /translation="MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFA
                     GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYND
                     PAAALIITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
                     IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHL
                     DVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVV
                     AESEEIALEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNS
                     HAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCP
                     TETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQD
                     ILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDF
                     RANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNF
                     AITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEI
                     LRQGREMIQWSSPKPQNGDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSG
                     GADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARL
                     AAENLREKILFRGAQMLGEPVADVQLATPGVVRGKKGEVSFGDIAHKGETGTGFGSLV
                     GTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGAT
                     LRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKS
                     ISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI"
     gene            complement(58160..58939)
                     /locus_tag="RH288_000286"
     CDS             complement(58160..58939)
                     /locus_tag="RH288_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     FAD-binding subunit"
                     /protein_id="HDV4029389.1"
                     /translation="MIEQFFRPDSVEQALELKRRYQDEAVWFAGGSKLNATPTRTDKK
                     IAISLQDLELDWVDWDNGALRIGAMSRLQPLRDARFIPAALREALGFVYSRHVRNQST
                     IGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLACPCDRLLTEIIIKDPYRT
                     CATRKISRSQAGLTVVTAAVAMTDHDGMRIALDGVASKALRLHDVEKQNLEGNALEQA
                     VANAIFPQEDLRGSVAYKRYITGVLVADLYADCQQAGEEAV"
     gene            complement(58990..60318)
                     /gene="ssnA"
                     /locus_tag="RH288_000287"
     CDS             complement(58990..60318)
                     /gene="ssnA"
                     /locus_tag="RH288_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417355.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDV4029390.1"
                     /translation="MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDA
                     SFKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEES
                     LYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRDAFLKVGLRAMTCFETTDRN
                     NGIKELQEGVEENIRFARLIDEAKKATSEPYLVEAHIGAHAPFTVPDAGLEMLREAVK
                     ATGRGLHIHAAEDLYDVSYSHHWYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDITLL
                     NQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGG
                     PLWPDSFAKALTNGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIA
                     FGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA"
     gene            complement(60321..63419)
                     /gene="ygfK"
                     /locus_tag="RH288_000288"
     CDS             complement(60321..63419)
                     /gene="ygfK"
                     /locus_tag="RH288_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenate reductase subunit YgfK"
                     /protein_id="HDV4029391.1"
                     /translation="MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKGKTV
                     SVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAED
                     ECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
                     PPMQQFIDNMMDASDHPKFAQYRDTLNKLLQDDAFLARHGLQEKRESLQALPARIPTS
                     MVHGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGY
                     IGLKEESFDHDLKLTQALEMLERLMALAKEKSLGFGVKLTNTLGTINNKGALPGEEMY
                     MSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKP
                     GGYLRLSACMRELEGSDAWGLDHVDVERLNRLAADALTMEYTQKHWKPEERIEVAEDL
                     PLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQ
                     YNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPAGSGSRHPVAVIGAGPAGLAAG
                     YFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVAAHGVKFEYGCSPD
                     LTIEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVV
                     VVGAGNTAMDCARAALRVPGVEKATIVYRRSLQEMPAWREEYEEALHDGVEFRFLNNP
                     ERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLLVDSLITAIGEQQDTEALNAMG
                     VPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDAILSRENIRSH
                     QNDKYWNNVNPAEIYQRKGDISITLVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPN
                     RANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLAQDFDNSS
                     NPGFLVEDCRVRVRLNNQSWVLNIDSKGQFNNVPPELNDMCRIISHVHQHHHYLLGRV
                     EV"
     gene            complement(63741..64319)
                     /gene="mocA"
                     /locus_tag="RH288_000289"
     CDS             complement(63741..64319)
                     /gene="mocA"
                     /locus_tag="RH288_000289"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDV4029392.1"
                     /translation="MSAIDCIITAAGLSSRMGQWKMMLPWEQGTILDTSIKNALQFCS
                     RIILVTGYRGNELHERYANQSNITIIHNPDYAQGLLTSVKAAVPAVQTEHCFLTHGDM
                     PTLTIDIFRKIWSLRNDGAILPLHNGIPGHPILVSKPCLMQAIQRPNVTNMRQALLMG
                     DHYSVEIENAEIILDIDTPDDFITAKERYTEI"
     gene            64422..65192
                     /gene="yqeC"
                     /locus_tag="RH288_000290"
     CDS             64422..65192
                     /gene="yqeC"
                     /locus_tag="RH288_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDV4029393.1"
                     /translation="MKSIVDPSALVIDLGAQKRPTVISVVGAGGKTSLLFWLAELLQA
                     SGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASLTSPISFCFHSWKANQGKVQGFT
                     PEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHTLGAKV
                     STENVHRWSQFADITGLTPDATLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQC
                     ENAIAQSELLQPLQQHDVEAIWLGDIQEHPAIARRFVN"
     gene            65240..66865
                     /locus_tag="RH288_000291"
     CDS             65240..66865
                     /locus_tag="RH288_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDV4029394.1"
                     /translation="MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSI
                     VGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGM
                     RPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAV
                     EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLRQLREKGVAEE
                     HIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGA
                     GDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSA
                     EAMKLTERGFIPVMVDPACSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFT
                     AGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVK
                     LGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFTSV
                     SDKARAIGGGVLEALMMLMHQGVKATKEVLEVA"
     gene            complement(67086..68018)
                     /gene="arcC"
                     /locus_tag="RH288_000292"
     CDS             complement(67086..68018)
                     /gene="arcC"
                     /locus_tag="RH288_000292"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDV4029395.1"
                     /translation="MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIV
                     THGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGI
                     NKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVV
                     ASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLA
                     EMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAA
                     ASFARSRAGREALITVLSKAKEGIEGKTGTVICQ"
     gene            complement(68066..69451)
                     /gene="hyuA"
                     /locus_tag="RH288_000293"
     CDS             complement(68066..69451)
                     /gene="hyuA"
                     /locus_tag="RH288_000293"
                     /EC_number="3.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311773.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-phenylhydantoinase"
                     /protein_id="HDV4029396.1"
                     /translation="MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEI
                     DATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCR
                     LRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKL
                     NDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAE
                     AIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYD
                     TEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCP
                     NGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVV
                     IIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRF
                     LRRKPFVPPVL"
     gene            complement(69504..70715)
                     /locus_tag="RH288_000294"
     CDS             complement(69504..70715)
                     /locus_tag="RH288_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDV4029397.1"
                     /translation="MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHR
                     IKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGME
                     TDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
                     EQSGIRPEFVVSTEPTDCQVYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPIL
                     GELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGAL
                     DEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEG
                     LFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMY
                     AAIPLSWLATE"
     gene            complement(70773..71969)
                     /gene="dpaL"
                     /locus_tag="RH288_000295"
     CDS             complement(70773..71969)
                     /gene="dpaL"
                     /locus_tag="RH288_000295"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDV4029398.1"
                     /translation="MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRP
                     TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSF
                     EHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
                     CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMR
                     EMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIV
                     NVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRI
                     ISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEG
                     KHAVAP"
     gene            complement(72027..73214)
                     /gene="ygeW"
                     /locus_tag="RH288_000296"
     CDS             complement(72027..73214)
                     /gene="ygeW"
                     /locus_tag="RH288_000296"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="knotted carbamoyltransferase YgeW"
                     /protein_id="HDV4029399.1"
                     /translation="MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAAL
                     KALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE
                     TVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC
                     DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFG
                     MDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKV
                     MEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADI
                     SGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQE
                     RVK"
     gene            73693..75471
                     /locus_tag="RH288_000297"
     CDS             73693..75471
                     /locus_tag="RH288_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HDV4029400.1"
                     /translation="MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAG
                     TGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTP
                     VILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
                     IFATMIDNMDQGVLVVDDENRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTH
                     GHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGEC
                     RVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPE
                     QLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAR
                     EILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQED
                     IELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGE
                     VIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREALSRHNSK
                     KQVADELGIGIATLYRKIKKYELLNT"
     gene            complement(75511..75990)
                     /gene="xdhC"
                     /locus_tag="RH288_000298"
     CDS             complement(75511..75990)
                     /gene="xdhC"
                     /locus_tag="RH288_000298"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase iron sulfur-binding
                     subunit XdhC"
                     /protein_id="HDV4029401.1"
                     /translation="MNHSETITIECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGC
                     CVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQ
                     CGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK"
     gene            complement(75987..76865)
                     /gene="xdhB"
                     /locus_tag="RH288_000299"
     CDS             complement(75987..76865)
                     /gene="xdhB"
                     /locus_tag="RH288_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase FAD-binding subunit XdhB"
                     /protein_id="HDV4029402.1"
                     /translation="MFDFASYHRAATLADAINLLADNPQAKLLAGGTDVLIQLHHHND
                     RYRHIVDIHNLAELRGITLAEDGSLRIGSATTFTQLIEDPITQRHLPALCAAATSIAG
                     PQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSL
                     EHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFG
                     VAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMT
                     KKVISEAVAAAGGKLQ"
     gene            complement(76876..79173)
                     /gene="xdhA"
                     /locus_tag="RH288_000300"
     CDS             complement(76876..79173)
                     /gene="xdhA"
                     /locus_tag="RH288_000300"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdenum-binding
                     subunit XdhA"
                     /protein_id="HDV4029403.1"
                     /translation="MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVR
                     SPIAHGYAVSINDEQARSLPGVLAIFTWEDVPDIPFATAGHAWTLDENKRDTADRALL
                     TRHVRHHGDAVAIVVARDELTAEKAAQLVSIEWQELPVITTPEAALAEDAAPIHNGGN
                     LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSST
                     QIPHIVRRVVGQALDIPWSCVRVIKPFVGGGFGNKQDVLEEPMAAFLTSKLGGIPVKV
                     SLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGN
                     KVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEI
                     RLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVA
                     CFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVS
                     DVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNL
                     TLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVD
                     LTVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGV
                     VRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMA
                     TGVAINTLPLTPKRLYEEFHLAGLI"
     gene            79588..80343
                     /locus_tag="RH288_000301"
     CDS             79588..80343
                     /locus_tag="RH288_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417341.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDV4029404.1"
                     /translation="MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTV
                     KRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSITRKSTAKSTT
                     KTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYA
                     AGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGST
                     DAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            80422..80495
                     /locus_tag="RH288_000302"
     tRNA            80422..80495
                     /locus_tag="RH288_000302"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:80454..80456,aa:Gly,seq:ccc)
     gene            80639..>81089
                     /locus_tag="RH288_000303"
     CDS             80639..>81089
                     /locus_tag="RH288_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001338841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029405.1"
                     /translation="MEYFMKGKSALTLLLAGIFSCGTCQATGAEVTSESVFNILNSTG
                     AATDKSYLSLNPDKYPNYRLLIHSAKLQNEIKSHYTKDEIQGLLTLTENTRKLTLTEK
                     PWGTFILASTFEDDKTAAETHYDAVWLRDSLWGYMALVSDQGNSVAAK"
BASE COUNT        19701 a        20079 c        21398 g        19911 t
ORIGIN      
        1 tgttatatct ataactcaat gttatataag aaattaataa ttcactgttt tcaaaacacc
       61 ggtttccctg ctcaattgct ttcattaaac cgcacgagta ttttattttt accgccggac
      121 ggtaccctaa aaataaaata aggataattt atgcggctta gtgattattt tccagaatca
      181 tcaatctcag ttatacattc agcaaaagat tggcaggaag ctatcgattt ctcgatggta
      241 tcattgctgg ataaaaacta tatcagcgag aattacattc aggcaattaa agattccacc
      301 attaacaatg gcccttatta tattctcgca ccaggcgtgg caatgcctca tgcgcgaccg
      361 gaatgtgggg cgcttaaaac cgggatgtct ttgacattac ttgaacaagg tgtttatttt
      421 ccggggaatg acgaaccaat taaattactc atcggactct ctgctgccga tgccgattcg
      481 cacattggcg ctattcaggc gttaagtgaa ttactgtgcg aagaagaaat actcgaacaa
      541 ctcttaacag catcatcaga aaaacaatta gcggacatta tcagccgcgg ataattactc
      601 tctcctctac aggataatat tatggaaaac aagtctgctc gtgcaaaggt ccaggctttt
      661 gggggctttt tgactgcaat ggtcatcccc aatattggtg cttttattgc ctggggtttt
      721 attactgcgt tatttattcc caccggttgg ctgcctaacg aacatttcgc caaaattgtc
      781 ggcccgatga ttacctattt attgcccgtg atgattggtt ctacaggtgg tcatctggtc
      841 ggcggtaaac gcggggcggt catgggcgga ataggtacta ttggtgtgat cgttggcgca
      901 gagatcccga tgttccttgg ctcaatgatc atggggccgc tcggtgggtt ggtcataaaa
      961 tatgtcgata aggcactgga aaaacgcata cctgccggtt ttgagatggt tatcaataac
     1021 ttctcattag gtatcgcggg gatgctcctt tgtctgctgg gttttgaagt tatcggcccg
     1081 gcggtgttaa ttgccaatac tttcgtcaaa gagtgtattg aggcgctggt acatgcgggt
     1141 tatctgccat tgttgtcagt catcaatgaa ccggcgaaag tgcttttcct caataatgcg
     1201 atcgatcagg gcgtctatta tccgctggga atgcaacagg cttcggttaa cggtaaatcc
     1261 atcttcttta tggtggcctc taacccaggt ccgggcctgg ggctgctgct ggcgtttacc
     1321 ttgtttggta aagggatgag taaacgttct gcgcccgggg cgatgattat tcacttcctc
     1381 ggtgggatcc acgaactgta tttcccgtat gtgctgatga agccgctgac cattattgcc
     1441 atgattgcgg gcggtatgtc tggcacctgg atgtttaact tactggacgg tggtctggtg
     1501 gctggcccaa gtccggggtc tatctttgct tacctggcac tgacgccgaa aggctcgttc
     1561 ctggcgacaa ttgccggtgt tacggtaggt accctggtgt cctttgctat tacttcgctg
     1621 atactgaaga tggaaaaaac ggtggaaacg gagagcgaag atgagtttgc tcagtcagcc
     1681 aatgcggtta aggcgatgaa acaagagggt gcattctcgt taagcagggt taagcgtatc
     1741 gcctttgttt gcgatgcggg gatgggctcc agtgcgatgg gcgcgaccac cttccgtaaa
     1801 cgcctggaaa aagcggggct ggcaattgaa gtaaaacatt acgccataga aaacgtgcct
     1861 gcggatgcgg atatcgtcgt tactcatgcc agtctggaag ggcgcgtgaa acgtgtgacg
     1921 gataaaccac tgatattgat taataactat attggcgatc caaaactcga cactttattt
     1981 aatcaattaa ccgccgaaca taaacactga ttacagaggt aaaaatgaaa accaaagttg
     2041 ctgctattta tggcaagcgg gatgtccgtc tgcgcgtatt tgaactgcca gaaattaccg
     2101 ataatgaatt actggtgagt gtaatttctg acagcgtctg tttatcgacc tggaaagcgg
     2161 cgttactcgg tagtgaacat aaacgcgtac ccgacgattt agaaaatcat ccggtcatta
     2221 ccgggcatga atgtgccggg gttattgtcg aagtgggtaa aaatctcact ggcaaatata
     2281 aaaaaggcca gcgttttgta ttgcaaccgg cgatggggtt accaagcgga tattcagcgg
     2341 gctacagcta cgaatatttt ggcggcaatg ccacttatat gattattccc gaaatcgcca
     2401 ttaatttggg ctgcgtatta ccgtatcacg gctcttattt tgctgcggcg tcgctggcag
     2461 agcctatgtg ctgcattatt ggtgcttatc atgccaatta tcacaccacg caatatgttt
     2521 atgagcatcg catgggcgtc aaacctggcg gcaatattgc actgctggcg tgtgcaggtc
     2581 cgatgggcat tggcgctatc gattacgcca ttaacggcgg catacaaccg tcgcgggtgg
     2641 tggtggtcga tatcgacgac aaacgtctgg cgcaggtaca gaagctgctg ccggtggaac
     2701 tggcggccag taaaggcatt gagctggtgt atgtgaatac caaagggatg agcgatcctg
     2761 tccagatgct gcgggcgctg acaggagatg ccgggttcga tgacattttt gtttatgcgg
     2821 cggtgcctgc tgtcgttgag atggctgatg aattactggc ggaagatggc tgtctgaact
     2881 tctttgccgg gccgacggat aaaaacttca aagtgccgtt taatttctac aacgtccatt
     2941 acaacagcac gcacgtcgtc ggtacatctg gcggttcaac ggacgacatg aaagaggcga
     3001 ttgcccttag cgccactggg cagttacagc cgtcgtttat ggtgacccat atcggtggcc
     3061 tggatgcggt gccagaaacc gtgctcaatc tgccggatat ccctggcggt aaaaaactca
     3121 tttataacgg cgtgaccatg ccgctcactg ccattgccga ttttgccgaa aaaggcaaaa
     3181 ccgatccgct gtttaaagag ttggcgcggc tggttgagga aacgcacggc atctggaatg
     3241 aacaggccga gaaatatctg ctggcacaat ttggcgttga tatcggggag gccgcgcaat
     3301 gatgtccctg gcgtggccat tatttcgcgt tacggaacag gcagcgttgg ctgcctggcc
     3361 gcaaaccgga tgtggcgaca aaaataaaat tgatggcctg gcggtcaccg cgatgcgcca
     3421 ggcattaaac gacgtcgctt ttcgtggacg agtggttatc ggcgaaggag aaattgacca
     3481 tgcgccgatg ctgtggattg gcgaagaggt gggcaaaggc gatgggccag aagtcgatat
     3541 cgcggttgat cccattgaag gcacgcggat ggtggcgatg gggcagagca atgcgctggc
     3601 ggtcatggct ttcgcccctc gagatagcct gttacatgcg cccgatatgt atatgaaaaa
     3661 gctggttgtt aatcggctgg cggcgggcgc gattgatctg tctttgcctc tgacggacaa
     3721 cctgcgcaac gtggcgaaag cgttaggcaa accgctggat aagctgcgca tggttacgct
     3781 ggataaaccg cgcctgagtg ccgcgattga ggaagcaaca cagctgggcg tgaaggtttt
     3841 tgccctgccg gatggcgatg tcgccgccag cgtgctgacc tgctggcagg ataatcctta
     3901 cgatgtgatg tacaccatcg gcggtgcgcc agaaggcgtg atttctgcct gtgccgttaa
     3961 agcattaggc ggggatatgc aggccgagct gattgacttt tgccaggcta aaggggatta
     4021 cacggaaaat cggcagattg cagagcagga gcgcaagcgt tgcaaggcaa tgggcgttga
     4081 cgttaaccgt gtgtactcgc tcgatgaact ggtgaggggg aacgatatcc tctttagcgc
     4141 tacgggcgtg acgggcggtg agctggtgaa cggtatccaa cagacggcga atggggtgcg
     4201 gacgcagaca ttactgatcg gcggcgcgga ccaaacgtgt aatataatag actccctgca
     4261 ttgatggtga tctatcggaa gaccaatggc gacgctgaca gaagatgatg tgcttgagca
     4321 actggatgca caggacaatt tattttcatt tatgaaaact gcgcatacca ttttgctcca
     4381 ggggatacgc cagtttctgc cgtcgctgtt tgtcgataac gatgaagaga tcgtggaata
     4441 tgcagtgaag ccgttactcg cccaaagcgg cccgcttgac gatattgatg ttgcactgcg
     4501 tttgatttat gcgttgggga aaatggataa atggttgtac gccgatatca cgcatttttc
     4561 ccagttctgg cattacctga acgaacagga tgaaacgccc ggatttgccg atgacatgac
     4621 ctgggatttt atcagcaacg tcaatagcat aacccgcaat gcgatgctct atgacgcgtt
     4681 aaaagcgatg aagttcgctg atttctccgt ctggtcagag gcgcgtttta gcggaatggt
     4741 caaaacggcg ctgacgctgg cagtaacgac caccttaaag gaattaacgc cgtgaaaatt
     4801 gaattaacgg tgaatgggct gaagatacag gcacagtacc agaacgaaga gattgaaaat
     4861 gtacataaac cgttgctgca catgttggcg gccttacaga cggtaaatcc gcagcggcgt
     4921 acggtggttt ttctttgcgc tccgccgggg acgggtaaat caaccctaac caccttctgg
     4981 gaatatctcg cgcaacaaga cccggaactg cccgctattc agacgctccc gatggatggt
     5041 tttcaccatt acaatagctg gctggatgcg catcaattgc gccccttcaa aggcgcacca
     5101 gagacatttg acgttgcgaa actgacggaa aatctgcgcc aggtcgtgga aggggattgt
     5161 acgtggccgc agtacgatcg acaaaagcat gatcctgttg aagatgcgtt gcacgttacc
     5221 gcaccactcg tcatcgtcga aggaaactgg ttgttactgg atgatgaaaa gtggctggag
     5281 ttggcatctt tctgcgattt ttctattttt attcatgcac ctgctcaaat tctgcgggag
     5341 cgcttgatta gtcgtaaaat tgcgggagga ttaacgcggc aagtagccga agcattttat
     5401 gcccgcaccg atggccccaa tgtcgagcgt gtgctgatga atagccgtca ggccaatctg
     5461 atagtagaga tgactgaaga aggccggtat cacttcacaa gctgacaatt tattccagtt
     5521 attgtagggt tattattacg ccagcctgga ataaagcttc ccacaaaagg ggataaaagt
     5581 gtgatgtgag tcagataaat gtcttcttcg gctggacaaa cattcctttt attccacgtt
     5641 tcgcttatcc tagctgaagc gtttcagtcg attaaatgtt cgacaattaa ccaatcagtc
     5701 gcagtttgcg acaggtaagg tttccccgga cgatttgctg gattactctg tctggcaaat
     5761 ttgctcaggg aaaaccttgc aggagatcta tgaccgtacg cgtagcgata aatggcttcg
     5821 gtcgcatcgg gcgtaatgtg gttcgtgctt tgtatgaatc cggacgccgg gcggaaatta
     5881 ccgtggtggc aatcaacgaa ctggcggatg ctgcgggcat ggcgcatttg ttgaaatatg
     5941 acaccagcca tggccgtttt gcatgggaag tacgacagga acgcgatcaa ctttttgttg
     6001 gtgatgacgc catccgcgta ttgcatgaac gttcactgca atcgctcccc tggcgtgaac
     6061 ttggcgttga tgtagtcctc gactgcaccg gcgtatatgg ctcccgcgag catggcgaag
     6121 cgcatattgc cgccggggcc aaaaaagtgc tcttttcaca tcctggcagt aacgatctcg
     6181 acgcgaccgt tgtttacggc gtcaatcagg atcaacttcg tgcggaacac cgcatcgttt
     6241 ctaacgcttc ctgtaccacg aattgcataa ttcccgtcat caaattgtta gatgatgcgt
     6301 acggtattga gtccggcact gtgaccacaa ttcactccgc catgcacgat caacaggtta
     6361 ttgatgcata ccatcctgac ctgcgtcgca cccgggcagc cagccagtcg atcattccgg
     6421 tcgatactaa actggccgcc ggtatcacac gattttttcc gcaatttaac gatcgctttg
     6481 aagcgattgc ggtacgtgtg ccaaccataa atgtgacggc aatcgattta agcgtgacgg
     6541 tgaagaaacc tgtaaaagcc aatgaagtca acctgttgct gcaaaaagca gcacaaggtg
     6601 catttcatgg tatagttgac tatacggaat tgccgttggt ctctgtagat tttaaccacg
     6661 atccgcacag tgccattgtc gatggcaccc aaacccgggt cagtggcgca cacctgatca
     6721 aaacgttggt ctggtgcgat aacgaatggg gctttgctaa ccgaatgctc gacacgacgt
     6781 tagctatggc tactgttgct ttcaggtaag acgcaagcag cgtctgcaaa acttttagaa
     6841 tcaacgagag gattcaccat gtctgtaatt aagatgaccg atctggatct tgctgggaaa
     6901 cgtgtattta tccgtgcgga tctgaacgta ccagtaaaag acgggaaagt aaccagcgac
     6961 gcgcgtatcc gtgcttctct gccgaccatc gaactggccc tgaaacaagg cgcaaaagtg
     7021 atggtaactt cccacctggg tcgtcctacc gaaggcgagt acaacgaaga attctctctg
     7081 ctgccggttg ttaactacct gaaagacaaa ctgtctaacc cggttcgtct ggttaaagat
     7141 tacctcgacg gcgttgacgt tgctgaaggt gaactggttg ttctggaaaa cgttcgcttc
     7201 aacaaaggcg agaagaaaga cgacgaaacc ctgtccaaaa aatacgctgc actgtgtgac
     7261 gtgttcgtaa tggacgcatt cggtactgct caccgcgcgc aggcttctac tcacggtatc
     7321 ggtaaattcg ctgacgttgc gtgcgcaggc ccgctgctgg cagctgaact ggacgcgctg
     7381 ggtaaagcac tgaaagaacc tgctcgcccg atggtggcta tcgttggtgg ttctaaagta
     7441 tctaccaaac tgaccgttct ggactccctg tctaaaatcg ctgaccagct gattgttggt
     7501 ggtggtatcg ctaacacctt tatcgcggca caaggccacg atgtgggtaa atccctgtac
     7561 gaagctgacc tggttgacga agctaaacgt ctgctgacca cctgcaacat cccggttccg
     7621 tctgatgttc gcgtagcaac cgagttctct gaaactgcac cggctaccct gaaatctgtt
     7681 aacgatgtga aagctgacga gcagatcctg gatatcggtg atgcttccgc tcaggaactg
     7741 gctgaaatcc tgaagaatgc gaaaaccatt ctgtggaacg gtccggttgg cgtgttcgaa
     7801 ttcccgaact tccgcaaagg tactgaaatc gtggctaacg ctatcgcaga cagcgaagcg
     7861 ttctccatcg ctggcggcgg cgacactctg gcagcaatcg acctgttcgg cattgctgac
     7921 aaaatctcct acatctccac tggcggcggc gcattcctcg aattcgtgga aggtaaagta
     7981 ctgcctgcag tagcgatgct cgaagagcgc gctaagaagt aaaaaatcac agggcaggga
     8041 aacctgccct tgtttcagcg cgcttttaga gcacgcaatt tttcatactc taaataattc
     8101 gagttgcagg aaggcgacaa gagagtgaat ccccaggagc ttacataagt aagtgactgg
     8161 ggtgagcgaa cgcagacgca gcacatgcaa cttgaagtat gacgagtata aggcccgacg
     8221 atacaggaca agagacatgt ctaagatttt tgatttcgta aaacctggcg taatcactgg
     8281 tgatgacgta cagaaagttt tccaggtagc aaaagaaaac aacttcgcac tgccagcagt
     8341 aaactgcgtc ggtactgact ccatcaacgc cgtactggaa accgctgcta aagttaaagc
     8401 gccggttatc gttcagttct ccaacggtgg tgcttccttt atcgctggta aaggcgtgaa
     8461 atctgacgtt ccgcagggtg ctgctatcct gggcgcgatc tctggtgcgc atcacgttca
     8521 ccagatggct gaacattatg gtgttccggt tatcctgcac actgaccact gcgcgaagaa
     8581 actgctgccg tggatcgacg gtctgttgga cgcgggtgaa aaacacttcg cagctaccgg
     8641 taagccgctg ttctcttctc acatgatcga cctgtctgaa gaatctctgc aagagaacat
     8701 cgaaatctgc tctaaatacc tggagcgcat gtccaaaatc ggcatgactc tggaaatcga
     8761 actgggttgc accggtggtg aagaagacgg cgtggacaac agccacatgg acgcttctgc
     8821 actgtacacc cagccggaag acgttgatta cgcatacacc gaactgagca aaatcagccc
     8881 gcgtttcacc atcgcagcgt ccttcggtaa cgtacacggt gtttacaagc cgggtaacgt
     8941 ggttctgact ccgaccatcc tgcgtgattc tcaggaatat gtttccaaga aacacaacct
     9001 gccgcacaac agcctgaact tcgtattcca cggtggttcc ggttctactg ctcaggaaat
     9061 caaagactcc gtaagctacg gcgtagtaaa aatgaacatc gataccgata cccaatgggc
     9121 aacctgggaa ggcgttctga actactacaa agcgaacgaa gcttatctgc agggtcagct
     9181 gggtaacccg aaaggcgaag atcagccgaa caagaaatac tacgatccgc gcgtatggct
     9241 gcgtgccggt cagacttcga tgatcgctcg tctggagaaa gcattccagg aactgaacgc
     9301 gatcgacgtt ctgtaagata ttcctttctg cttatctcaa ggcccgctct gcgggtcttt
     9361 ttttcgccaa aagcaaaatt gcctgatgcg ctacgcttat caggcctaca cgtatcctgc
     9421 aatatattga atttgcaggt ttttgtaggc cggataaggc gttcacgccg catccggcat
     9481 gacaaagcgc acattgatat ctgtctgagc cccgctctgc ggggattttt tcgccaaaag
     9541 caaggtgatt cagatgagaa atctgtgatc tatttggcaa aattatgctt tattgtttac
     9601 ccttgtcaga ctgcccgtca taaggcggcg gagtgtattt ctccattttg agtcagttga
     9661 aaaggaatat tgaatggaag atttgaatgt tgtcgatagc ataaacggcg cgggaagctg
     9721 gctggtagct aaccaggcgc tgctgctaag ttatgcagta aacatcgtgg cggcactcgc
     9781 gatcatcatc gttggtttga ttatcgcgcg gatgatttcc aacgcggtga atcgcctgat
     9841 gatctcccgt aaaatcgatg ccactgttgc tgattttctt tctgcattag tccgttacgg
     9901 tattatcgcc tttacgctaa tcgctgcact gggacgcgtg ggtgtacaaa ccgcgtcagt
     9961 cattgctgta ctcggtgccg caggcttagc tgttggtctg gctttgcagg ggtcactgtc
    10021 taacctggcc gctggcgtgt tacttgtcat gttccgcccg ttccgtgccg gagaatatgt
    10081 tgacctgggc ggcgtagccg gtactgtgct gagtgtgcag attttctcca ccaccatgcg
    10141 tactgcagac ggtaaaatta tcgttattcc gaacggtaaa attattgccg gaaatattat
    10201 taacttctcc cgcgagccag ttcgccgtaa cgaatttatt attggcgtgg cgtatgattc
    10261 cgatatcgat caggttaagc agatcctgac caatattatc cagtctgaag atcgcatttt
    10321 gaaagatcgc gaaatgactg tgcgcctgaa cgaacttggt gcatcgtcga ttaatttcgt
    10381 ggtccgcgtc tggagcaaca gcggcgatct gcaaaacgtg tactgggatg tgctggagcg
    10441 tattaaacgt gaatttgatg ccgccggtat cagcttcccg tacccgcaaa tggatgtgaa
    10501 ctttaagcgg gtgaaagaag acaaagctgc gtaatcaacg ctgaggccag ataatactct
    10561 ctggcctctc tcttattagt ttttctgatt gccaattaat attatcaatt tccgctaata
    10621 acaatcccgc gatatagtct ctgcatcaga tacttaattc ggaatatcca acgtgttttc
    10681 ttattacttt caaggtcttg cacttggggc ggctatgatc ctaccgctcg gtccacaaaa
    10741 tgcttttgtg atgaatcagg gcatacgtcg tcagtaccac attatgattg ccttactttg
    10801 tgctatcagc gatttggtcc tgatttgcgc cgggattttt ggtggcagcg cgttattgat
    10861 gcagtcgccg tggttgctgg cgctggtcac ctggggcggc gtagccttct tgctgtggta
    10921 tggttttggc gcttttaaaa cagcaatgag cagtaatatt gagttagcca gcgccgaagt
    10981 catgaagcaa ggcagatgga aaattatcgc caccatgttg gcagtgacct ggctgaatcc
    11041 gcatgtttac ctggatactt ttgttgtact gggcagcctt ggcgggcaac ttgatgtgga
    11101 accaaaacgc tggtttgcac tcgggacaat tagcgcctct ttcctgtggt tctttggtct
    11161 ggctcttctc gcagcctggc tggcaccgcg tctgcgcacg gcaaaagcac agcgcattat
    11221 caatctggtt gtgggatgtg ttatgtggtt tattgccttg cagctggcga gagacggtat
    11281 tgctcatgca caagccttgt tcagttaggc gctatctgat ggaaaaataa aacagaggcg
    11341 ctaagcttgc ctccagaggt cctgaatttt gggcaagtca attaacacgg agagactaac
    11401 gtgaagttca aagttatcgc cctggcggca ttaatgggta ttagcgggat ggcagcgcag
    11461 gctaacgaat tgccggatgg accgcatatt gtcacctccg gtacggcaag cgtggatgcg
    11521 gtgccagaca ttgccactct tgcgattgaa gttaacgtgg ccgcgaagga tgccgctact
    11581 gccaagaaac aggcagatga gcgcgtcgca caatacattt ccttccttga actcaatcag
    11641 atcgcgaaaa aagatatcag ctcagcgaac ttacgcaccc agccagatta tgattatcag
    11701 gatggtaaaa gtatccttaa aggctaccgc gctgtgagaa cggtggaagt cacgctccgt
    11761 cagttagaca aactgaattc cttgctggat ggcgcgctga aggcgggtct taacgaaatt
    11821 cgttctgtgt cgctgggcgt ggcgcagccg gatgcctata aagacaaagc gcgtaaggca
    11881 gcgattgata acgcgattca tcaggcgcag gaactggcga acggctttca tcgtaaactg
    11941 gggccggtat atagcgtgcg ctaccatgtt tccaactatc agcccagccc aatggtgcgg
    12001 atgatgaaag ccgatgccgc gccggtgtcc gcccaggaaa cttacgagca ggccgctatt
    12061 cagtttgatg atcaggtcga tgtggtcttc cagttagaac ctgtggatca acaacccgct
    12121 aaaacacctg cagcacaata atatttgtag cccgacgtat tcgtcgggct aatgccttta
    12181 cccgatattg cctccttttt ctgtaatttt ctgtaaaacc atgacgtaat cacctatctt
    12241 tgctcgcggt ttcatcaagg ataggctgac tgaaacggtt aagcggacaa ggatgcgggg
    12301 gagggggatg gacattttta tttcgaaaaa gatgcgcaat ttcattttat tagcgcaaac
    12361 caataatatt gcccgggcgg cagaaaaaat ccatatgacg gcttcgccat ttggtaaaag
    12421 cattgccgcg ctggaagaac aaattggcta tacgctattt acccgcaaag ataataatat
    12481 cagcctcaat aaagccggac aggaactgta tcaaaaactg ttcccggttt atcaacggct
    12541 ttctgcgatt gataatgaaa tccataactc agggcgtcgt tcacgagaaa ttgtgattgg
    12601 catagataat acttatccga caattatttt cgatcagttg attagtctcg gagataagta
    12661 tgaaggcgtg accgcccagc cagttgagtt cagcgaaaat ggcgttatcg ataatctttt
    12721 tgaccgccag ttagatttta ttatctcccc acagcatgta tctgcacgag ttcaggaact
    12781 ggaaaacctg actatcagtg aactaccacc gctgcgatta ggctttctcg tttctcgccg
    12841 ttatgaagag cgacaagagc aagagctgct tcaggagctg ccctggctac aaatgcgctt
    12901 tcagaaccgg gccaacttcg aagcaatgat tgatgcgaat atgcgacctt gtgggatcaa
    12961 tccaaccatt atttatcgtc cctacagttt tatggccaaa atcagcgccg tggagcgcgg
    13021 acattttctg acggtgatcc cgcattttgc ctggcgactg gtgaatccgg caacgctgaa
    13081 atattttgat gcaccgcaca ggccgatgta tatgcaggaa tatctttatt caatcagaaa
    13141 tcatcgttat accgccacga tgcttcagca tattgctgaa gatcgtgacg ggacgagtca
    13201 ttaacccagc atcgagccgg ttgcaattaa attacggtgt aagtcgaaga cgtggctaag
    13261 atcgtggtga atatgtccgc caggcgcatt ttccagatag cgatgcagat aatcccgata
    13321 cataggatgt gcacaattat caatgatagt gcgggcgcgt tgaagcgggg aaagaccgcg
    13381 cagatcggcg atcccttgtt cggtgatgat cactttgacg ctgtgttcgc tgtgatcaac
    13441 atggctgcac attggcacga cggttgagat cttgccttct ttagcaatcg acggggccat
    13501 aaagatcgac agatacgcgt tgcgttcaaa atcaccgctg ccgccgatgc cgttcatcag
    13561 atcgaccccg gctacgtgtg ttgagttggc atgcccgtaa atatcaaact ccaggccgac
    13621 gttcagagcg atgacgccca gacgacggat gatttccggg ttattggaaa tctcctgcgg
    13681 acgcaacaca atgcggctgg caaagtaatc catattgtcg taaatcttgc gcagggaatc
    13741 ggccgagatt gtcaggctgg aggcgctggc cccgctgatt ttgccggttt ccagtaaatg
    13801 caccaccgat tcctgtagca cttccgaata catcataaac ggaggaatta ccgggttttc
    13861 ccccagacgc gccattaccg cattattgat attgcccacg ccactttgca gcggcagaaa
    13921 ttccggcgga atacgcccat gcgccatttc ctgcaataag aacgtgacca cgttatcggc
    13981 aatctgctgg cacatgggat tttgcttatc cagcatatta ccggcgtcgg gcaagttggt
    14041 ttccacgacg gcgacaatct ttttcggatc gatttgcaca tagcgggtac cgacgcgatc
    14101 cattgcatgg aagatcgaca cgctattgcg ccgcggtggc gcgccaggaa tcacaatatc
    14161 cgccagttct gcaacgcgcg gatcgtgata gtgattgagt tcaatgatca ctttcttcgc
    14221 ccgcagcagc caggtcggcg cattaccgat cccgctggtt aaccagactc gaccatccgg
    14281 tgccagtgcc gatgcttcaa tgacggcaac atcaatgtcg ccgaagaaac cgtaattgac
    14341 catttgcgcc acttcgctca aatgcaggtc aacgaaactc accgcgccct gattgatctt
    14401 tttacgtaaa ccggacgatg tttgatatgg cgcacgccag gaaacagcat cggcgtcaga
    14461 aagtacatcg tcagcggcgg cgctgattga cgcacccgtc agaaggcgaa tttgatacgg
    14521 ctttttggcc tcatgctgtt cgttagctct gcgggcaatc gcggtgggta gggctttcgg
    14581 cgaacccgcc ggggtaaagc cgctaaatgc caccatgtcg ttatgctgga taatttctgc
    14641 cgcttcattg gcggtcatcc ttgtccactg agtttccatt tttactcctt cgttcgcagg
    14701 gattaatgac caacgaaatt aggtttacgt ttttcgagga aagcgttcat cccttcctgg
    14761 taatcttcgc tgtcatacac cgcgcggcgc atcccctgaa tacgttcaaa ttcatcggag
    14821 ttcatggtgt gtgcttcgcc cagtacacgc agctcttctt tgataacggc aatggctaac
    14881 ggcgctttct cagagatgtg gtgcgccatt tgtaaggtga aatcttccag ttcttccact
    14941 tccacaacat ggttgaggat gccgacagcc agcgcgcgct gggcggtgat tggcgaagcg
    15001 gtaaaaatca gctctttgac aatgtggaag cccgcgtcgc gggtcaggtt gtgaatgccg
    15061 accaggttat acgggacgcc gaggtttaca ggcgtcattg agaaggttga ggtactggcg
    15121 gcgatgatca gatcggaact catgatcatt tcaaatgcgc caccccaaac actaccttcc
    15181 accatcgaaa tgatcggttt cgggaatttt tggatcatgc gggtgatttg acgcaatgga
    15241 tcatcatagg agagcggatc gcgaccgcca gacggcagtt cgtgaatatc gtgacctgcg
    15301 gagaagactt tggatccact cggtgcgcgc aaaatgatac agcgaatttc cggccggttg
    15361 agatcgctta acgcctgcat aagatcatca ataaagactt tacttaaggc attaagtttt
    15421 cggccatagt taaactcaat gaccgccact ttgttgatag tgacaacgtt aacatactga
    15481 taagacataa aaattccttt aatcaaaata ttgcgtctgg ataaattcac tgagctgccg
    15541 caggccggtg cgcggtgaga gcgtattgtt tttgaccgct aaaagcgtct ggcggtaata
    15601 gcgatcgaaa tcttcattcg cgaacaggtg attcagtact tcttcttcgg tctgcttacg
    15661 cagccattcc accgattgtt gttgccgcac ttgttgtaaa cgaccactgg cagttagcgc
    15721 ggttttgaag tcgatgatgg cgtgccagat ctcatcgatt ccacgttttt ccagtgcgct
    15781 acaagtcaga acccgtggct gccattcgtc gtatttacgt cgcagaatat gcagggcact
    15841 ctcgtacata tgccgggcaa tggcgacatt ggtatggtta tcgccatcgt ctttgttgat
    15901 aacgatcaga tcagccactt ccatcagccc ttttttaatg ccctgcagat catcgccgcc
    15961 accggcaatt tgcaacgaga taaaacagtc caccatgcgg gcgacttctg tttccgactg
    16021 cccgacgcca accgtttcga caatcactac gtcataaccc gctgcttcgc ataacagcat
    16081 taattcccgc gctcgctgac tggcaccgcc cagatgaccg gaggatggta ccgggcgaat
    16141 aaacgccgct tcggcacgcg ccaggtcatt catgcgggtt ttatccccga gaatgctacc
    16201 gccagtgacc gggctgctgg gatcgaccgc aataaccgcg acctttaatc cctctcgaat
    16261 caacaacatg ccaaaggcct caagaaaggt acttttcccc gcgccggggg tgccggtaac
    16321 gcccagtcgc agggtgttac cgcagtacgg cataatggca tcaagcagct gcgtacttag
    16381 tgcctgatga cgcgggtgac ggctttccac cagcgtcatg gcctgggcga gtgtggcacg
    16441 ctcaccctga cgtaagcggc gaatactttc tgccagcgtg gcttcattaa tcatgatgct
    16501 ggcttatcag attcagtacg tcgcgcacac tgtcgagcat aggtgtacct ggaccataaa
    16561 tcgccgccac gccgcgctct tgcaggaagg cgtaatcctg cggcggaatg acgccacccg
    16621 cgaccacgca gatatcttcg cgtccccatt ttttcagcgc ttcgaccagt tccgggatca
    16681 gcgttttatg accggcagcc agtgaggatg cgcccactac gtgaacgtcg ttttctacgg
    16741 ccaggcgggc gatctcttca ggtgtagaga acatcgggct taaatctacg tcgaaaccga
    16801 gatcggaata ggcgctggcg atcactttcg cgccgcgatc gtgtccatcc tggcccatct
    16861 tagcgatcag aatgcgcggg cgacgaccat tgtcggcaag gaactgctcc gtttgcgcaa
    16921 caatggcatc gaactcggag gccgatttct cagactgatg atagctttgc gcaatcacgc
    16981 cggtaacaca ctggcttggc accagataac ggtcgaaagc gacttccagc gcatcggaaa
    17041 tttcacccag ggtggcgcga acgcgagcgg cattaacagc ggcagccagc aggttttcgt
    17101 tatgctgtgc ggcgtgagtc agggcgttca acgcggcggt tacggcggca tcatcacggg
    17161 tggcgcgaat gcgttccagc gaagcaattt gctcgttacg caccatcacg ttgtcgatct
    17221 caagtacatc ggtttcgtct tcgtgatcca gtttgtactt gttgacacca acgatgacac
    17281 gcttgccctg gtcgatcagc gactgttcgc gcgctgaggc ctcttcgatc attcgttttg
    17341 gcagacctgc ttcgatcgct ttcgccatgc caccggcttc gtcgatctgt tggataatag
    17401 ctctggcttg tttgacgatt tgatcggtca gcgactcaat gtaataggat ccggccagtg
    17461 gatcgacggt gcggcagagt tctgattctt cctggatgat gatctgggtg ttgcgggcaa
    17521 tgcgtgctga gaaatcggta ggcaaaccaa gcgcttcgtc aaaggcgttg gtatgcagtg
    17581 actgagtacc gcccagcgtc gcagccagcg cttcaatggt ggtgcggata acgttgttat
    17641 acggatcctg ttcagtcagg ctccagcctg aggtctggca gtgggtacgc agcgccagtg
    17701 atttcgggtc ctgtgcgcca aatccactga ccgcttcgct ccataaataa cgtgccgcac
    17761 gcaacatggc gacgttcata aacagatcca tgccgatgcc gaagaagaac gacaggcgag
    17821 gagcgaagtc atcaattttc agtccggcag agattgctgc tttgatgtac tcaatcccat
    17881 cagcgagcgt aaatgctacc tgctgcacgc agttggcacc cgcttcaccc atgtggtaac
    17941 cgctgatact gatggtatta aatcgcggca tgttgccgga acaccaggcg atgatgtcgg
    18001 cgataatgcg cattgacggt tttggtgggt aaatataggt gttgcggcag aggtactctt
    18061 tgagaatatc gttttgaatg gtgccggtca gtttatcagg tgtaacacct tgctcttctg
    18121 cggcgacgat ataaaacgcc agtactggta gcactgcgcc attcatggtc atcgaaaccg
    18181 acattttatc cagcgggatc tggtcgaaca ggactttcat atcttccacg gtgtcgatag
    18241 cgacgcccgc tttgccgacg tcgcccgcca cgcgcgggtt atcggagtcg tagccacggt
    18301 gggtggcaag gtcaaacgca acggaaagac ctttttgccc ggcggccagg ttacggcgat
    18361 aaaaagcgtt ggactctttt gctgttgaaa aaccagcata ctgacggatg gtccacggtt
    18421 gggcggtata catagtggca cgcgggccac gaacgtaggg cggcaaacca ggaagggtac
    18481 ctgtcacctc cagattatcg agatcggctt cggtatacag cggcttgatg gcgatccctt
    18541 ccgcggtttg atgaaccagc gagtcgacag ttttctcccg acggctcaat tccttgttgg
    18601 caagctgttg ccactcctgc acgttagaca ttatttgctc cgtaaaacgc aatcaaaatg
    18661 agggtatttg cgcctacggt gagcttttta cgtgggtttg tcgccagcaa aaaaaatgca
    18721 ttcagacgtc gttttttgcc gcctgagatt tgtctatttt gtgatgtgat tcaaggaata
    18781 caaaaagaag tgaggacaac gcctgatatg tgctatcagg cattatttga tggattaatc
    18841 ctgacgaagg actttgtgac cataatcgag taacgcatca gtgactttac gcatcatgcg
    18901 gctttcagga gcaaagcggt gccagtagag catccgtcgt tgaaatagcc caggcgttaa
    18961 gtcaatcagt tcaccgctgg ccagctcttt ctcgatttgc aggtgcggga tcatacagca
    19021 ggtggtgccc tggcgagcaa gttgtacgaa cgcttctgaa gaattaacga tatggcaggg
    19081 cacgctgcct ggaggcagat cgaagttttg ctgcaaaaag gcctggtgca tatcgtcaag
    19141 atggtcaaac gcgaccactg gcgctttcag taatgccgaa cgcgttacgc cgttagggaa
    19201 atatttttcg gcaaagggtt ttgagctgac gaacagatag tcgagcgcac caagtttatc
    19261 gacaagacaa ctcggcagcg cctgatgttg aatactcacc gcgccgacca cttcgccgcg
    19321 gcgcagacgt tcctgagtgc gggtttcatc ttctacctgc aagttgaggc ggataggcga
    19381 atcagccaac acaggagcca gtgcaggaag caaccacgtc gccagactgt cggcgttgac
    19441 cgccagtgaa agcagcagcg gagtcgaacc ggtttgttca tcgcccagcc actcttcttc
    19501 cagcaactcc acctggcgca gcagtgccag cagtttttgc ccttgttccg tcgggcgcgg
    19561 cggtacggta cgcaccaaca gcggctgccc gaacatattt tccagttgct taatgcgctg
    19621 tgagacggct gattgtgtaa tgcacagctt ttgtgccgcg cgctcaaatc ctcgttcacg
    19681 tatcaccgca tccagtgcct gtaatgttct gtagtccggg cgtttcattg ctgttgtctg
    19741 ctcctggtaa atgctttttc ctgcactatg acacaatttt gtgtcaggtt gcatataccg
    19801 aagccgtcgg cgggtaacat ttgtattcgt ggttaaacgc gcagcttaaa agatcaggga
    19861 tttgcgctaa tgcatttcgc tcagcgagtt cgcgccctgg ttgtgttgaa tggcgtggcg
    19921 ttattgcctc aatttgcctg taaacagggg cttgtgaacg gtgaactggt gcgcctgttt
    19981 gctccgtgga gcggcatacc cagattgttg catgccttat ttgcgggcga aaggggatgc
    20041 ctgccattgc gcgatatttt atggatgagt taaccacgcg gcttgccaac ggggtctgaa
    20101 tcgctttttt tgtatataat gcgtgtgaaa tttcatacca caggcgaaac gatcatgacg
    20161 caggatgaat tgaaaaaagc agtaggatgg gcggcacttc agtatgttca gcccggcacc
    20221 attgttggtg taggtacagg ttccaccgcc gcacacttta ttgacgcgct cggtacaatg
    20281 aaaggccaga ttgaaggggc cgtttccagt tcagatgctt ccactgaaaa actgaaaagc
    20341 ctcggcattc acgtttttga tctcaacgaa gtcgacagcc ttggcatcta cgttgatggc
    20401 gcagatgaaa tcaacggcca catgcaaatg atcaaaggcg gcggcgcggc gctgacccgt
    20461 gaaaaaatca ttgcttcggt tgcagaaaaa tttatctgta ttgcagacgc ttccaagcag
    20521 gttgatattc tgggtaaatt cccgctgcca gtagaagtta tcccgatggc acgtagtgca
    20581 gtggcgcgcc agctggtgaa actgggcggt cgtccggaat accgtcaggg cgtggtgacc
    20641 gataatggca acgtgatcct cgacgtccac ggcatggaaa tccttgaccc gatagcgatg
    20701 gaaaacgcca taaatgcgat tcctggcgtg gtgactgttg gcttgtttgc taaccgtggc
    20761 gcggacgttg cgctgattgg cacacctgac ggtgtcaaaa ccattgtgaa atgatctgac
    20821 gggggaacct cccccgttaa aaaaattctc ttcattaaat ttggtgacat gtgtcacgtt
    20881 tttacctggc tattgtcgat tgctctaaat aaatcttcta aaccagcata ttcatccaag
    20941 aattaccttt gcgtgatatt tcctcaacat cgcgacgcaa acgttcatat tgccgcaata
    21001 ttattttttg atatgttgaa aggcggacgc aaatccgcac acaacatttc aaaagacagg
    21061 attgggtaaa tggcaaaggt atcgctggag aaagacaaga ttaagtttct gctggtagaa
    21121 ggcgtgcacc aaaaggcgct ggaaagcctt cgtgcagctg gttacaccaa catcgaattt
    21181 cacaaaggcg cgctggatga tgaacaatta aaagaatcca tccgcgatgc ccacttcatc
    21241 ggcctgcgat cccgtaccca tctgactgaa gacgtgatca acgccgcaga aaaactggtc
    21301 gctattggct gtttctgtat cggaacaaac caggttgatc tggatgcggc ggcaaagcgc
    21361 gggatcccgg tatttaacgc accgttctca aatacgcgct ctgttgcgga gctggtgatt
    21421 ggcgaactgc tgctgctatt gcgcggcgtg ccggaagcca atgctaaagc gcaccgtggc
    21481 gtgtggaaca aactggcggc gggttctttt gaagcgcgcg gcaaaaagct gggtatcatc
    21541 ggctacggtc atattggtac gcaattgggc attctggctg aatcgctggg aatgtatgtt
    21601 tacttttatg atattgaaaa taaactgccg ctgggcaacg ccactcaggt acagcatctt
    21661 tctgacctgc tgaatatgag cgatgtggtg agtctgcatg taccagagaa tccgtccacc
    21721 aaaaatatga tgggcgcgaa agaaatttca ctaatgaagc ccggctcgct gctgattaat
    21781 gcttcgcgcg gtactgtggt ggatattccg gcgctgtgtg atgcgctggc gagcaaacat
    21841 ctggcggggg cggcaatcga cgtattcccg acggaaccgg cgaccaatag cgatccattt
    21901 acctctccgc tgtgtgaatt cgacaacgtc cttctgacgc cacacattgg cggttcgact
    21961 caggaagcgc aggagaatat cggcctggaa gttgcgggta aattgatcaa gtattctgac
    22021 aatggctcaa cgctctctgc ggtgaacttc ccggaagtct cgctgccact gcacggtggg
    22081 cgtcgtctga tgcacatcca cgaaaaccgt ccgggcgtgc taactgcgct gaacaaaatc
    22141 ttcgccgagc agggcgtcaa catcgccgcg caatatctgc aaacttccgc ccagatgggt
    22201 tatgtggtta ttgatattga agccgacgaa gacgttgccg aaaaagcgct gcaggcaatg
    22261 aaagctattc cgggtaccat tcgcgcccgt ctgctgtact aattcccctt ctctgaaaat
    22321 caacgggcag gtcactgact tgcccgtttt tttatccctt ctccacaccg ttgccgcgtt
    22381 gcgcattcta ctttgcgagt ctgctccaga aaataaatca aagtcagatc aatgcgttgt
    22441 gtttatttaa tggggattta cgatggcagg gcagcatggg gctgtaacgg taaagccctc
    22501 accgaagcga gggcttgaag gagaagggtt atgatgcgac ttgtcatcat actgattgta
    22561 ctgttactca taagtttcag cgcttattaa cagtcagtct caggggagga gcaatcctcc
    22621 cttaccctta ctcactaaat taggtcaaag aatcaacgat gtcaatcagg gcgatgcggg
    22681 tgtatcgccc ttaccactcc cagactttcg acggtgtaac caccgcagga agagggatat
    22741 cccactcttc aacggggagt ttttccacca actgacaatc atgcgcataa cccaccggtt
    22801 gcgttttata gtgctgccag ttttgtaagg tccgatcata aaaaccaccg cccattccca
    22861 ggcgctgacc gtactcatca aaggcgacca gcggtgtgat cagcacgtct aatcgggaaa
    22921 ggggtagcac gtcacgcaca tccaattttg gctcatggat cttcaacctg ttcatcacca
    22981 gttcgctttg cggatggtaa ttcaggaaca gcaaattacc ggcactaaag ggatgcaaaa
    23041 ctggaagata tacgcgctta ccggcgcgcc agagttgttc tatgagtggc tgggtgtcga
    23101 gttcgccatc aaaagagagg aatacagcga ccgtatgtgc catcaccacc gggggataag
    23161 tcatcatccg ggtagcggct tgttgaccca tttcctgctg ttgttccggc gttaacgcac
    23221 gacgacgttg ccgaatcatt ttgcggattt cttgtcggga taatgtcagt gggagttctg
    23281 gtagttgcgt catggctggt gccagataag aagggaatct ccgagatgcc gccgcaggct
    23341 gtaacccttg aacccttggt tcaaggtgaa tgtgtcgtcg cagttttaag gcttctcgga
    23401 cggaccgagc atgctcacca accgcggagc gccacattct tgtggtatga aatatcggct
    23461 caggggactg gcccgcttgc gaacatctca gagaaatttt gtcttcacgg ttactctacc
    23521 acagtaaacc gaaaagtgtc attcaaagtt ttggttagtt ttttcggtga tgcgaccttg
    23581 ttcaagtaac gcttgttcta tggtctgctg cagcatccga atacgctgtt ccatacttgc
    23641 cgcgtagtca cgagtctttg ctttttcttg cgctaactca tagctgatat tcaatgcggc
    23701 aatgaagacc aactgttcag tatttgtgac tctagtgcgt tctttcagat cttgcaaccg
    23761 ttggttcaga tcgtccgctg cctgattcaa cgcatccctt tggtcaggcg ggcagttcac
    23821 acgcagtgaa cggccaaaaa tttggatatc gacgggttgt gcagacatgc caccttcctg
    23881 ctgattgact gcgctgcctt cgtctttaga cccatggtct gcgaaggggc gacactatag
    23941 ctaccctgat gagaagagac aagccctttt ctggtccacc agggcccaaa gtggtagcat
    24001 atcatgaata ttcctccctt tgacgacgaa tgcttatgtc tatacagaac gaaatgcctg
    24061 gttacaacga aatgaaccag tatctgaacc aacaagggac gggtctgacc ccagctgaga
    24121 tgcatggttt aatcagcggg atgatatgtg gcggtaacga tgacagctca tggctaccgc
    24181 tacttcacga cctgacgaac gaaggcatgg ctttcggtca tgagctggca caggcactgc
    24241 gtaaaatgca ctctgccacc agcgatgccc tgcaggatga cggcttcctt tttcagcttt
    24301 atctgcctga tggcgatgat gtcagcgttt tcgatcgggc tgatgcattg gcaggttggg
    24361 tcaatcactt cctgcttggt cttggcgtta cgcaaccgaa gctggataaa gtgaccggcg
    24421 aaaccggtga agctatcgac gatctgcgta acattgcgca actgggttac gacgaagacg
    24481 aagatcagga agagcttgaa atgtcgcttg aagagatcat cgaatacgtt cgtgttgccg
    24541 cgctgttatg ccacgacacc tttactcatc cgcaaccgac cgcgccagaa gtacaaaaac
    24601 cgactctaca ctaaaaacaa aaaacgtaag gagagtgtta tgagtgagat atcccggcaa
    24661 gagtttcagc gtcgccgtca ggccctggtg gagcaaatgc aacccggcag cgccgcgctg
    24721 atttttgctg caccagaagt aacacgtagc gccgacagcg aataccccta tcgtcagaac
    24781 agtgacttct ggtacttcac cggctttaac gaaccggaag cggtgctggt gctgattaaa
    24841 agcgatgaca ctcataacca cagcgttctg tttaaccgcg ttcgcgacct gacggcggag
    24901 atctggtttg gccgtcgctt aggccaggat gccgcgccag agaaactggg cgttgaccgc
    24961 gcactggcat tcagcgaaat caatcagcaa ctttatcaac tacttaacgg cctggatgtg
    25021 gtttaccatg cccagggcga atatgcatat gctgatgtaa tcgtgaacag tgcgctggaa
    25081 aaactgcgta aaggttcgcg gcaaaatctc accgcaccgg caacgatgat cgactggcgt
    25141 cctgttgttc atgaaatgcg cctgttcaaa tcgccagaag agattgccgt actccgccgc
    25201 gcgggagaaa tcaccgccat ggcacataca cgggcgatgg aaaaatgccg tccgggaatg
    25261 ttcgagtacc atctggaagg cgaaattcac cacgaattta accgccacgg tgcgcgctat
    25321 ccgtcctata acaccattgt cggcagcggt gaaaacggct gcattctgca ctacaccgaa
    25381 aacgagtgtg aaatgcgcga cggcgacctg gtgttgattg acgcgggttg tgaatacaaa
    25441 ggttacgctg gcgatattac ccgcaccttc ccggtcaacg gcaaattcac ccaggcccag
    25501 cgtgaaatct acgacattgt gctggagtct ctcgaaacca gcctgcgcct gtatcgtccg
    25561 ggaacttcca ttctggaagt cactggtgaa gtggtgcgca tcatggttag cggcctggta
    25621 aaactcggca tcctgaaagg tgatgttgat gaactgatcg ctcagaacgc ccatcgtcct
    25681 ttctttatgc atggccttag ccactggtta ggactggatg tccatgacgt gggtgtttat
    25741 ggtcaggatc gctcgcgcat tctggaaccg ggcatggtac tgaccgtaga gccagggctg
    25801 tatattgcgc cggatgcaga agtgccagaa caatatcgcg gtatcggcat tcgtattgaa
    25861 gacgacattg tgattaccga aaccggtaac gaaaacctca ccgccagcgt ggtgaaaaag
    25921 ccggaagaaa tcgaagcgtt gatggttgct gcgagaaagc aatgagcgta atcatcgtcg
    25981 gtggcggcat ggcgggcgcg acgctggcgc tggctatttc ccggttaagt cacggggcgc
    26041 tgccggtaca tttgattgaa gcgactgcgc cagagtcaca tgctcatccg ggctttgatg
    26101 gacgagcgat agcgctggcg gcgggtacct gtcagcaact ggcgcgcatc ggcgtctggc
    26161 aatctctggc ggattgcgca actgccatca ccaccgtgca tgtcagcgat cgtggtcacg
    26221 ctggatttgt caccctcgcc gcagaagatt accaactggc ggcgctggga caggttgtcg
    26281 aattgcacaa tgtcgggcaa cggctgtttg cattgctgcg taaagcacct ggcgtaacgc
    26341 tgcattgccc tgatcgcgtg gctaacgttg cccgtactca gagtcacgtt gaagtgacgc
    26401 tggagagtgg cgagacgctg acgggccgcg tgctggtagc agctgatggc acccattcag
    26461 cgttagccac cgcgtgcggc gttgactggc agcaggagcc ttacgaacaa ctggccgtga
    26521 ttgccaacgt tgctacttcc gttgcgcatg aagggcgcgc ttttgaacgc tttacgcaac
    26581 atggcccgct ggcgatgttg ccgatgtctg acggacgctg ttcgctggtc tggtgtcatc
    26641 cactggaacg gcgcgaagag gtgttgtcgt ggagtgacga gaagttttgc cgtgaactcc
    26701 agtcgacctt tggctggcga cttgggaaaa ttacccacgc tggtaaacgc agtgcttatc
    26761 cgctggcgtt aacccacgcc gccagatcta ttacccatcg taccgtgctg gtgggcaatg
    26821 cggcgcaaac tctgcacccg attgccgggc aagggtttaa cctcggtatg cgagatgtga
    26881 tgagtcttgc ggaaaccctg actcaggcgc aggagcgcgg agaagacatg ggggattacg
    26941 gcgtattgtg ccgttatcag cagcgtcgac agagcgatcg cgaagcaacc attggcgtca
    27001 cggacagcct tgtacatctt tttgccaacc gttgggcacc gctggttgtc gggcgcaaca
    27061 tcgggctgat gacgatggaa ttattcaccc cggcacgcga tgtgctggcg cagcgcaccc
    27121 tcggttgggt ggcgcgttga aggcggtttt aaggaataaa caatgcaaag tgttgatgta
    27181 gccattgttg gcggcggcat ggtggggctg gcggttgcct gtggcttaca ggggagcggc
    27241 ttacgcgttg ccgtactgga gcagcgcgta caggaacctc tggcggcgaa tgcaccacca
    27301 caactgcgcg tttcggctat caatgccgcc agcgaaaaat tactcacccg tcttggcgtc
    27361 tggcaggaca ttctctctcg tagggccagc tgttatcacg gtatggaagt gtgggacaaa
    27421 gacagctttg gtcacatttc gtttgacgat caaagcatgg gctatagcca tcttgggcat
    27481 atcgttgaaa attcagtgat tcactacgcg ctgtggaaca aagcgcatca gtcgtcagat
    27541 atcactctgt tagcccccgc agaattacag caggtcgcct ggggagaaaa tgaaaccttc
    27601 ctgacgctga aagatggcag catgttaacg gcgcgtctgg tgattggcgc ggacggcgct
    27661 aattcctggt tgcgcaacaa agccgatatt ccgctgactt tctgggatta tcagcatcac
    27721 gcgctggtag cgaccattcg cacggaagaa ccgcatgatg cggtggcgcg gcaggttttc
    27781 catggcgaag gcattctggc ctttttaccg cttagcgatc cgcatctttg ctcgattgtc
    27841 tggtcactgt cgccagagga agcgcagcgg atgcagcagg caagtgaaga cgaatttaat
    27901 cgcgcgttaa atatcgcttt tgataatcgc ctgggcttat gcaaggttga gagcgcgcgt
    27961 caggtgttcc cactgacggg gcgttatgcg cgccagtttg cctcgcaccg tctggcgctg
    28021 gtgggcgacg ccgcacatac cattcacccg ctggcggggc agggggtaaa tctcggcttt
    28081 atggatgctg cagagctgat tgccgaactg aaacggttgc atcgtcaggg gaaagacatc
    28141 gggcagtaca tttatctgcg tcgctatgag cgtagccgca agcacagtgc ggcgttgatg
    28201 ctggctggta tgcagggatt ccgcgatctg ttttccggta ccaatccggc gaaaaaactg
    28261 ctgcgtgata ttggtttgaa actggccgac acgcttcctg gcgttaagcc gcaacttatc
    28321 cgccaggcaa tgggattaaa cgatttgcct gaatggctgc gttaaaaatt tctcctctgt
    28381 tgtttatttg atacccatca cactttcatc tcccggtttt ttcgccggga gattttcctc
    28441 atttgaaata aactaatttc acctccgttt tcgcattata ttttctaatg ccattatttt
    28501 ttgatttagt gttttttgac atttttttag ctcttaatat tgtcttattc aaattgactt
    28561 tctcatcaca tcatctttgt atagaaactg gtgtattttt tggtttttta ttctgtcgcg
    28621 atttttgcat tttttaacca taagctaatg tgatgatcaa ttttacctta tggttaacag
    28681 tctgtttcgg tggtaagttc aggcaaaaga gaacgattgc gttggggacc gggagtggct
    28741 ccgatgctgg gtttcgtggt gataatttca ccatgaaaaa gttgtcagcc ccgcttattc
    28801 aatgaggaca agatggcaca acagactcct ttgtacgaac aacacacgct ttgcggcgct
    28861 cgcatggtgg atttccacgg ctggatgatg ccgctgcatt acggttcgca aatcgacgaa
    28921 catcatgcgg tacgtaccga tgccggaatg tttgatgtgt cacatatgac catcgtcgat
    28981 cttcgcggca gccgcacccg ggagtttctg cgttatctgc tggcgaacga tgtggcgaag
    29041 ctcaccaaaa gcggcaaagc cctttactcg gggatgttga atgcctctgg cggtgtgata
    29101 gatgacctca tcgtctacta ctttactgaa gatttcttcc gcctcgttgt taactccgcc
    29161 acccgcgaaa aagccctctc ctggattacc caacacgctg aacctttcgg catcgaaatt
    29221 accgttcgtg atgacctttc catgattgcc gtgcaagggc cgaatgcgca ggcaaaagct
    29281 gccacactgt ttaatgacgc ccagcgtcag gcggtggaag ggatgaaacc gttctttggc
    29341 gtgcaggcgg gcgatctgtt tattgccacc actggttata ccggtgaagc gggctatgaa
    29401 attgcgctgc ccaatgaaaa agcggccgat ttctggcgtg cgctggtgga agcgggtgtt
    29461 aagccatgtg gcttgggcgc gcgtgacacg ctgcgtctgg aagcgggcat gaatctttat
    29521 ggtcaggaga tggacgaaac catctctcct ttagccgcca acatgggctg gaccatcgcc
    29581 tgggaaccgg cagatcgtga ctttatcggt cgtgaagccc tggaagtgca gcgtgagcat
    29641 ggtacagaaa aactggttgg tctggtgatg accgaaaaag gcgtgctgcg taatgaactg
    29701 ccggtacgct ttaccgatgc gcagggcaac cagcatgaag gcattatcac cagcggtact
    29761 ttctccccga cgctgggtta cagcattgcg ctggcgcgcg tgccggaagg tattggcgaa
    29821 acggcgattg tgcaaattcg caaccgtgaa atgccggtta aagtgacaaa acctgttttt
    29881 gtgcgtaacg gcaaagccgt cgcgtgattt acttttttgg agattgattg atgagcaacg
    29941 taccagcaga actgaaatac agcaaagaac acgaatggct gcgtaaagaa gccgacggca
    30001 cttacaccgt tggtattacc gaacatgctc aggagctgtt aggcgatatg gtgtttgttg
    30061 acctgccgga agtgggcgca acggttagcg cgggcgatga ctgcgcggtt gccgaatcgg
    30121 taaaagcggc gtcagacatt tatgcgccag taagcggtga aatcgtggcg gtaaacgacg
    30181 cactgagcga ttccccggaa ctggtgaaca gcgaaccgta tgcaggcggc tggatcttta
    30241 aaatcaaagc cagcgatgaa agcgaactgg aatcactgct ggatgcgacc gcatacgaag
    30301 cattgttaga agacgagtaa cggctttatt cctcttctgc gggagaggat cagggtgagg
    30361 aaaatttatg cctcaccctc actctcttcg taaggagaga ggttcacaat tcactgcacg
    30421 tttcaggaac catcgctcat gacacagacg ttaagccagc ttgaaaacag cggcgctttt
    30481 attgaacgcc atatcggacc ggacgccgcg caacagcaag aaatgctgaa tgccgttggt
    30541 gcacaatcgt taaacgcgct gaccggccag attgtgccga aagatattca aattgcgaca
    30601 ccaccgcagg ttggcgcacc ggcgaccgaa tacgccgcac tggcagaact caaggctatt
    30661 gccagtcgca ataaacgctt cacgtcttac atcggcatgg gttacaccgc cgtgcagcta
    30721 ccgccggtta tcctgcgtaa catgctggaa aatccgggct ggtataccgc gtacactccg
    30781 tatcaacctg aagtctccca gggccgcctt gaagcactgc tcaacttcca gcaggtaacg
    30841 ctggatttga ctggactgga tatggcctct gcttctcttc tggacgaggc caccgctgcc
    30901 gccgaagcaa tggcgatggc gaaacgcgtc agcaaactga aaaatgccaa ccgcttcttc
    30961 gtggcttccg atgtgcatcc gcaaacgctg gatgtggtcc gtactcgtgc cgaaaccttt
    31021 ggttttgaag tgattgtcga tgacgcgcaa aaagtgctcg accatcagga cgtcttcggc
    31081 gtgctgttac agcaggtagg cactaccggt gaaattcacg actacactgc gcttattagc
    31141 gaactgaaat cacgcaaaat tgtggtcagc gttgccgccg atattatggc gctggtgctg
    31201 ttaactgcgc cgggtaaaca gggcgcggat attgtttttg gttcggcgca acgcttcggc
    31261 gtgccgatgg gctacggtgg cccacacgcg gcattctttg cggcgaaaga tgaatacaaa
    31321 cgctcaatgc cgggccgtat tatcggtgta tcgaaagatg cagctggcaa taccgcgctg
    31381 cgcatggcga tgcagactcg cgagcaacat atccgccgtg agaaagcgaa ctccaacatt
    31441 tgtacttccc aggtactgct ggcaaacatc gccagcctgt atgccgttta tcacggcccg
    31501 gttggcctga aacgtatcgc taaccgcatt caccgtctga ccgatatcct ggcggcgggc
    31561 ctgcaacaaa aaggtctgaa actgcgccat gcgcactatt tcgacacctt gtgtgtggaa
    31621 gtggccgaca aagcgggcgt actgacgcgt gccgaagcgg ctgaaatcaa cctgcgtagc
    31681 gatattctga acgcggttgg gatcaccctt gatgaaacaa ccacgcgtga aaacgtaatg
    31741 cagcttttca acgtgctgct gggcgataac cacggcctgg acatcgacac gctggacaaa
    31801 gacgtggctc acgacagccg ctctatccag cctgcgatgc tgcgcgacga cgaaatcctc
    31861 acccatccgg tgtttaatcg ctaccacagc gaaaccgaaa tgatgcgcta tatgcactcg
    31921 ctggagcgta aagatctggc gctgaatcag gcgatgatcc cgctgggttc ctgcaccatg
    31981 aaactgaacg ccgccgccga gatgatccca atcacctggc cggaatttgc cgaactgcac
    32041 ccgttctgcc cgccggagca ggccgaaggt tatcagcaga tgattgcgca gctggctgac
    32101 tggctggtga aactgaccgg ttacgacgcc gtttgtatgc agccgaactc tggcgcacag
    32161 ggcgaatacg cgggcctgct ggcgattcgt cattatcatg aaagccgcaa cgaagggcat
    32221 cgcgatatct gcctgatccc ggcttctgcg cacggaacta accccgcttc tgcacatatg
    32281 gcaggaatgc aggtggtggt tgtggcgtgt gataaaaacg gcaacatcga tctgactgat
    32341 ctgcgcgcga aagcggaaca ggcgggcgat aacctctcct gtatcatggt gacttatcct
    32401 tctacccacg gcgtgtatga agaaacgatc cgtgaagtgt gtgaagtcgt gcatcagttc
    32461 ggcggtcagg tttaccttga tggcgcgaac atgaacgccc aggttggcat cacctcgccg
    32521 ggctttattg gtgcggacgt ttcacacctt aacctacata aaactttctg cattccgcac
    32581 ggcggtggtg gtccgggtat gggaccgatc ggcgtgaaag cgcatttggc accgtttgta
    32641 ccgggtcata gcgtggtgca aatcgaaggc atgttaaccc gtcagggcgc ggtttctgcg
    32701 gcaccgttcg gtagcgcctc tatcctgcca atcagctgga tgtacatccg catgatgggc
    32761 gcagaagggc tgaaaaaagc aagccaggtg gcaatcctca acgccaacta tattgccagc
    32821 cgcctgcagg atgccttccc ggtgctgtat accggtcgcg acggtcgcgt ggcgcacgaa
    32881 tgtattctcg atattcgccc gctgaaagaa gaaaccggca tcagcgagct ggatattgcc
    32941 aagcgcctga tcgactacgg tttccacgcg ccgacgatgt cgttcccggt ggcgggtacg
    33001 ctgatggttg aaccgactga atctgaaagc aaagtggaac tggatcgctt tatcgacgcg
    33061 atgctggcta tccgcgcaga aattgaccag gtgaaagccg gtgtctggcc gctggaagat
    33121 aacccgctgg tgaacgcgcc gcacattcag agcgaactgg tcgccgagtg ggcgcatccg
    33181 tacagccgtg aagttgcggt attcccggca ggtgtggcag acaaatactg gccgacagtg
    33241 aaacgtctgg atgatgttta cggcgaccgt aacctgttct gctcctgcgt accgattagc
    33301 gaataccagt aattcactga ttcgactatt ttctaaaggc gcttcggcgc ctttttagtc
    33361 agatgacaaa gtacaaaagt gctcagacag tcccctcgcc cctttgggga gagggttagg
    33421 gtgaggggaa caggccggca ctggcgcgaa tatttaccct caccccggcc ctctccctga
    33481 aagggcgagg gggaaaagcg tgccaacatt gaagattgag ccagtttgtt agcaatctca
    33541 aagatacgtc aacgaattaa tttttctcgg aaaaacaaat ggctatagca cttgtgactg
    33601 gtggcagtcg cggcatcggg cgggcaactg cattactgtt ggcgcaagaa gggtatacgg
    33661 tggcggttaa ttatcagcaa aacctccacg cggcgcagga agtgatgaac ttaataacgc
    33721 aagccggtgg caaagcattc gtgctccagg cggatatcag cgacgaaaac caggtcgttg
    33781 cgatgtttac agcaatcgat cagcacgatg aaccgctagc agcgctggtc aataacgccg
    33841 ggatcttgtt tacccagtgc accgttgaaa accttaccgc agagcgaatc aaccgagtac
    33901 tttccaccaa cgtgacggga tattttctct gctgccgcga ggcggtaaaa cgcatggcgc
    33961 ttaaaaatgg tggcagtggc ggcgctatcg tcaatgtctc ttcggtggcc tcacggttgg
    34021 gttcgccagg ggaatatgtt gattacgcgg catcgaaagg ggcgattgat acgttaacca
    34081 ccggactatc gctggaagtc gccgcgcagg ggatccgcgt taactgcgtg cggccagggt
    34141 ttatttatac cgaaatgcac gccagcggcg gcgagcctgg acgcgtcgat cgcgttaagt
    34201 cgaacatccc catgcagcgt ggtggacagg cagaagaggt cgcgcaggcc attgtctggc
    34261 tactaagtga taaagcctct tacgtcacgg gaagttttat cgatttggcg ggcgggaaat
    34321 aaaacaggga agttgtctga ccggatgcaa caagtattgc atccggtact tcatcgactt
    34381 aaagcttctc gccgttgctg gcaatcacct ctttgtacca gttaaagctc ttcttacgtg
    34441 aacgcgacat atcgccagta ccgtcgtcat gtttattcac atagataaag ccgtagcgtt
    34501 tgctgtactg cccggtggtg aacgacacgc agtcgatgca gccccacggt gtgtagccca
    34561 tcagatccac gccatcgtaa gtcaccgctt ttttcatctc ttcgatatgg gcgcgcaggt
    34621 agtcaatgcg gtagtcgtcg ttgatgctgc catcttcttc cactttgtcg taagcgccaa
    34681 aaccgttttc gacaataaac agcggcctct gataacgctc atacagttcg caaagtgcat
    34741 agcgcagacc tactggatca atctgccagc cccagtcaga tgctttaaca tacgggtttg
    34801 gtacgctgcc ttcaaaacca gagatcgcat cgccggtgcc gccttcggcc ttcactgcat
    34861 tggtcatgta atagctgaaa ccaagataat cgcaggtgcc ttcacgcagc acatccagat
    34921 cgccgtcttc cattttgatg ttaaatccgc gacgctccca ctcgttcaac acataggacg
    34981 ggtaatagcc gcgtagctgc acatcggtaa agacgtagcg ttcgcgcatc gactcctgag
    35041 cgaacatcac atcgtccggg ttacaggagt aaggatagag cggcaccatc gccagcatac
    35101 agccgacttt catctccggg ttaatgcgac gcgcagcttt caccgccagg gcgctggcga
    35161 caaactggtg atgcagcacc tgatacatcg tctcttccgg gttttcatgc tcggtataca
    35221 ccacgccgga gcagcagtaa ccgaacagcg gtgcacgcca gttacgctgg ttgttaattt
    35281 cgttgaaggt catccagtat ttgactttgt gcttatagcg ttcaaatacc acttccgcga
    35341 aacgtacaaa gaaatcaacc actttacggt tggtccagct accgtattgc tgcaccagat
    35401 gcagcggcat ttcaaagtgg gagagggtga tcaccggttc gatgttgtat ttcagcagtt
    35461 catcgaacat atcatcgtag aacttcagcc cttcttcgtt tggctgagct tcatcgcctt
    35521 ttggaaaaat gcgcgtccag gcaatggatg tacgaaaaca tttgaagccc atttcggcaa
    35581 atagcttgat gtcttcctta tagtgaccat aaaaatcaac ggcttcatgg tttggatagt
    35641 attttcctgg caagacttct ttggtgattt cgcgcggcac gccgtgtgcg ccaccggtca
    35701 gaacgtcaca aatgctcggc ccttttccgc ctttgttcca gccgccttcg acctgatgag
    35761 cggcaactgc gccgccccat aagaaatctt tcggtaaggt gagttttttc actatcatag
    35821 gctccagatg agtcaattct tacaggaaat agtaccatgc agccaaacga catcactttt
    35881 tttcaacgtt tccaggatga cattctggct gggcgtaaaa ccatcaccat ccgcgacgag
    35941 tctgaatcgc acttcaaaac gggtgatgtg cttcgtgtcg gacgttttga agatgacggt
    36001 tatttttgca cgattgaagt caccgcaacc tcaaccgtaa cgctggatac gctgactgaa
    36061 aaacatgcag agcaggaaaa tatgaccctg actgaactga aaaaagtcat tgctgacatc
    36121 tatcccggtc agacacaatt ttatgtgatt gaatttaaat gtctttaaat tgaactcacg
    36181 cctgttagtt gaaatttcgc atttaatttc atgattttta ggagattagt ctcaaatcag
    36241 aatttatttt agctaacagg tgttcactgg aactattctc agttacgctg gagaggtata
    36301 catgtgcgtg tacgtttctc cggagtaagt tatggttcag aagcccctca ttaagcaggg
    36361 atattcgctg gcagaggaaa ttgccaacag cgtcagtcac ggcattgggt tggtgtttgg
    36421 tatcgttggg ctggtgttgc tactggttca ggcggtggat ctcaatgcca gcgccacagc
    36481 gataaccagt tacagcctct atggcggcag tatgatcctg ctgttcctcg cttcgacgct
    36541 ctatcacgcc attcctcatc aacgggcaaa aatgtggctg aagaaatttg accattgcgc
    36601 tatttacctg ttgattgccg gaacctacac gccgtttttg ctggtggggc tggattctcc
    36661 gttagcgcgc gggttgatga ttgttatctg gagcctggca ttgctgggta ttctgtttaa
    36721 actgaccatc gcgcaccgat tcaaaatttt atctctggtg acctatctgg cgatgggctg
    36781 gctgtcgctg gtggtaattt atgaaatggc agttaagctc gcggcgggca gcgttacctt
    36841 actggcggta ggcggcgtgg tttattcgct cggggtgatt ttctacgtct gcaaacgcat
    36901 tccatacaac catgccatct ggcacggctt cgtgctcggc ggtagtgtgt gccactttct
    36961 ggcgatctat ttgtatattg ggcaggcgta atgggtatgc ctttgtaggc ctgataagac
    37021 gcgccagcgt cgcatcaggc atcggagcac aactgccgga ttcggcgtga acgccttatc
    37081 cgatctacgg gcctcgtccc tgttgtgata aaggcatcaa atcccagaca tgataagacg
    37141 cgccagcgtc gcatcaggcg ataaatgcct gatgcgataa agagatttac tcttcgagcg
    37201 aatacggcag cggctcgata tgcaatgtat tcgcatcgtc gcgtacgcgg aagatgctat
    37261 ccggttccat atcgttattc atgacgacct gtaccacgac ctgaccatct tccagtttta
    37321 ccgcagccag caccgtaccg gtacgacgcc agttctcgcc cattttcagc tctaagtctt
    37381 caccagcttc cggcagtcgg ctggcgctac ctgccagcaa ccagagcgca cgtttattgg
    37441 caccacggaa ttttgctcgc gccaccatct cttgtccggt ataacagcct ttcttaaagc
    37501 tgataccgcc cagcgcctgg agattggtcg cctgtgggat aaactgcccg ctgttggcgg
    37561 catcaatcac cgggaaaccc gcttcaatgt ttaatgccag ccactgttgg ctattgttca
    37621 gttccgcttc accgcgcagt ttatcggtca gcatattagc agtagcttca tcggttacga
    37681 tcaggaaacg ttctgccggg tgttcaaacc atagcaaagt ggtcgcgcct tctttgacta
    37741 cctgtttttc tttcgaaggc agttcgctaa agagatttgc cagcgcggcg cgcgcctgaa
    37801 aaccggcaac accaagcagc acacgctcgt cgtctggcgc gatggtcact ttagagaata
    37861 ccgcatattt tttcagttca gtcagctgcg gttcacgcac gctgcgccgt tcaatccatg
    37921 caaagccatc gccgtcgcgg aacagacgta aattgctcca cattttacct ttggcgtcgc
    37981 aatgggcggc gagcaggtgc tgatcttctg ccatctggct gacatctgct gtcacctgac
    38041 cctgcatata tttttcgctg tccgcgccag taatggtggc aagcgcccag tcatcaagcg
    38101 tcatcagcgt cagcggtaaa cgggcagaag ccgtaggctg acggggagga aaaggtgtaa
    38161 aagccataat agagtcctga gttgcttaac ggcgtattaa tgactaatgg taaaagagct
    38221 atgaggcaat gcaagtgctt tcactacgcg atctgtgcct tctgcgaggc gacttccaaa
    38281 aaaatgaagc cattgaattg ttgtgaatta atttcgcgat cgcgatggtg tttactgata
    38341 ttcccgtaaa agaaggcgaa aaacacgtta caatagccgg gtactggatt ttcgtgagac
    38401 aggaagaaga tggacattaa caacaaagcc cgcattcatt gggcatgccg ccgtggtatg
    38461 cgcgaactcg atatttcaat catgccgttt ttcgaacatg agtacgacag cttaagcgat
    38521 gacgaaaaac gcatctttat tcgtctgctg gaatgtgacg atccggacct gtttaactgg
    38581 ctgatgaatc acggtaaacc ggccgatgca gaactggaaa tgatggtccg actcatccag
    38641 acacggaacc gggaacgtgg tcctgtggca atctgatttg cgcgtctcct ggcgcgcaca
    38701 gtggctttcc ttgctgattc atgggctggt tgccgctgtt attttactca tgccctggcc
    38761 actcagttac accccgttat ggatggtgtt actttcgctg gtggtgtttg attgcgttcg
    38821 cagccagcgg cgtattaatg ctcgccaggg ggaaattcgc ttgttgatgg acgggcgttt
    38881 gcgttggcaa gggcaggagt ggagcatcgt caaagcaccg tggatgatta agagcggcat
    38941 gatgctgcgt ttacgttctg atggcggtaa acggcaacat ttatggctgg cagccgacag
    39001 catggacgaa gctgaatggc gggatttacg gcggattttg ttgcaacaag agacgcaaag
    39061 ataaagatga cggcaaagca tatgcgctaa gccgtcagtg agatcaggcg taatgctctg
    39121 ccatttcgtt gaggatttgc tcgcaccagc tctgaatacg ctcgtcgcta aggtcatact
    39181 ggttagtttc atccagcgcc agacccacga acagttgccc gtcagcaatc accggtttcg
    39241 ggctggtaaa ttcatatcct tccgttggcc agtagccgac gaacttcacg cctttggtcg
    39301 agagtttgtc atgcagcata ccgagcgcat cgaggaacca ctcgccgtat cccagttgat
    39361 cgccaagccc atacagcgca acaattttac cttcaaggtt caggtcgtcg agctgatccc
    39421 agacggcttc ccagtcttcc tggatttcac caaaatccca ggtcgggata cccagaatga
    39481 gcacatcgta ctgctccatt aatttcgggg agtcgtcctt gaggttatgt aaggtcacca
    39541 gttctgggcc gataatatcg cggatttttt ctgccgccat ttcggtgtaa caggtgctgg
    39601 aaccgtaaaa aagacccata ttcataacgt aagcttctcg attctgctgt ggcttttgca
    39661 gctagtgtat cagaatcgct ttagtcacgg cacaataagg cataatggat caaatgagtg
    39721 accataaggg gcgcaagtga aacaggatct ggcacgcatc gagcagtttc ttgatgctct
    39781 gtggctggaa aaaaatctgg ctgaaaatac gttgaacgct taccgtcgcg atctgtcaat
    39841 gatggtggag tggttgcatc accgcgggtt gacgctggcg acggcgcaaa gtgacgattt
    39901 gcaggcatta ctggcagaac ggctggaggg cgggtataaa gccaccagct cagcgcgttt
    39961 gctgagtgca gtgcgccgat tgttccagta tctttatcgc gaaaagtttc gtgaagacga
    40021 tcccagtgcg catctcgctt caccgaaatt gccacagcgt ttgccaaaag atttaagcga
    40081 agcgcaggtc gaacgtttat tacaggcacc attaattgat cagccactgg agctacgcga
    40141 taaagccatg cttgaagtgt tgtatgctac cgggctgcgt gtctctgaac tggtcggact
    40201 gacaatgagt gatatcagcc tgcgtcaggg cgtagtgcgg gtcattggta aaggcaacaa
    40261 agagcgcctg gtgccgttag gtgaagaggc ggtttactgg ctggaaacgt atctcgagca
    40321 tgggcgaccg tggttgttga acggtgtctc tattgatgtg ttgttcccca gccagcgtgc
    40381 gcagcagatg acgcgacaga ccttctggca ccgcattaaa cattatgccg tgctggcggg
    40441 tatcgacagc gaaaagctgt caccgcatgt gttgcgtcac gcttttgcca cccatttatt
    40501 aaatcatggt gcggatttac gcgtggtgca gatgctactg ggccacagcg acctctccac
    40561 cacgcaaatt tatacgcatg tcgctaccga gcgtctgcgg caacttcatc aacagcatca
    40621 cccgcgggcg tgatgtctga aaagaacggg aagatttatg aagaaaggtt ttatgttgtt
    40681 tactttgtta gcggcgtttt caggttttgc tcaggctgat gacgcggcaa ttcaacaaac
    40741 gttagccaaa atgggcatca aaagcagcga tattcagccc gcgcccgtag ctggcatgaa
    40801 gacagttctg actaacagcg gcgtgttgta catcaccgat gatggtaaac atatcattca
    40861 ggggccaatg tatgacgtta gcggcacggc tccggtcaat gtcaccaata agatgctgtt
    40921 aaagcagttg aatgcgcttg aaaaagagat gatcgtttat aaagcgccgc aggaaaaaca
    40981 cgtcatcacc gtgtttactg atattacctg tggttactgc cacaaactgc atgagcaaat
    41041 ggcagactat aacgcgctgg ggatcaccgt gcgttatctt gctttcccgc gccaggggct
    41101 ggacagcgat gcagagaaag aaatgaaagc tatctggtgt gcgaaagata aaaacaaagc
    41161 gtttgatgat gtgatggcag gtaaaagcgt cgcaccagcc agctgcgacg tggatattgc
    41221 cgaccattac gtacttggcg tccagcttgg cgttagcggt actccggcag ttgtgctgag
    41281 caatggcaca cttgttccgg gttaccagcc gccgaaagag atgaaagaat tcctcgacga
    41341 acaccaaaaa atgaccagcg gtaaataatt cgcgtgaaac aacagataca acttcgtcgc
    41401 cgtgaagtcg atgaaacggc agacttgccc gctgaattgc ctcccttgct gcgccgttta
    41461 tacgccagcc ggggcgtgcg cagtgcgcaa gaactggaac gcagtgttaa aggtatgttg
    41521 ccctggcagc aactgagcgg cgtcgaaaag gccgttgaga tcctttacaa cgcttttcgc
    41581 gaaggaacgc ggattattgt ggtcggcgat tttgacgccg acggcgcgac cagcacggct
    41641 ctaagcgtgc tggcgatgcg ctcgcttggt tgcagcaata tcgactatct ggtaccaaac
    41701 cgtttcgaag acggttacgg cttaagcccg gaagtagtcg atcaggccca tgcccgtggc
    41761 gcgcagttaa ttgtcacggt ggataacggt atttcctccc atgcgggcgt tgaacacgct
    41821 cgctcgttgg gcattccggt tattgttacc gatcaccatt tgccgggcga aacattaccc
    41881 gcagcggaag cgatcattaa ccctaacttg cgcgactgta atttcccgtc gaaatcactg
    41941 gcaggcgtgg gtgtggcgtt ttatctgatg ctggcgctgc gcaccttttt gcgcgatcag
    42001 ggctggtttg atgagcgtgg catcgcaatt cctaacctgg cagaactgct ggatctggtc
    42061 gcgctgggaa cagtggcgga cgtcgtgccg ctggacgcta ataatcgcat tctgacctgg
    42121 caggggatga gtcgcatccg tgccggaaag tgccgtccag ggattaaagc gctgctggaa
    42181 gtggcaaacc gtgatgcaca aaaactcgcc gccagcgatt taggttttgc gctggggcca
    42241 cgtctcaatg ctgccggacg actggacgat atgtccgtcg gtgtggcgct cttgctgtgc
    42301 gacaacatcg gcgaagcgcg cgtgctggca aatgaactcg atgcgctaaa ccagacgcga
    42361 aaagagatcg aacaaggaat gcaagttgaa gccctgaccc tgtgcgagaa actggagcga
    42421 agtcgcgaca cgctacccgg cgggctggca atgtatcacc ccgaatggca tcagggcgtt
    42481 gtcggtattc tggcttcgcg catcaaagag cgttttcacc gtccggttat cgcctttgcg
    42541 ccagcaggtg atggtacgct gaaaggttca ggtcgctcca ttcaggggct gcatatgcgt
    42601 gatgcactgg agcgattaga cacactctac cctggcatga tactgaagtt tggcggtcat
    42661 gcgatggcgg cgggtttgtc gctggaagag gataaattcg aactctttca acaacggttt
    42721 ggcgagctgg ttaccgagtg gctggaccct tcgctattgc aaggcgaagt ggtgtcagac
    42781 ggcccgttaa gcccggccga aatgaccatg gaagtggcgc agctgctgcg cgatgctggc
    42841 ccgtgggggc agatgttccc ggagccgctg tttgatggtc atttccgtct gctgcaacag
    42901 cggctggtgg gcgaacgtca tttgaaagtc atggtcgaac cggtcggcgg cggtccgctg
    42961 ctggatggta ttgcttttaa tgtcgatacc gccctctggc cggataacgg cgtgcgcgaa
    43021 gtgcaactgg cttacaagct cgatatcaac gagtttcgcg gcaaccgcag cctgcaaatt
    43081 atcatcgaca atatctggcc aatttagcgt catcttctct ataaaaaaga gcgtggattg
    43141 ggtacaatcc cgctcttatc accgcatttt gactagctca ataaaagaaa tcagaccatg
    43201 tttgaaatta atccggtaaa taatcgcatt caggacctca cggaacgctc cgacgttctt
    43261 agggggtatc tttgactacg acgccaagaa agagcgtctg gaagaagtaa acgccgagct
    43321 ggaacagccg gatgtctgga acgaacccga acgcgcacag gcgctgggta aagagcgttc
    43381 ctccctcgaa gccgttgtcg acaccctcga ccaaatgaaa caggggctgg aagatgtttc
    43441 tggtctgctg gaactggctg tagaagctga cgacgaagaa acctttaacg aagccgttgc
    43501 tgaactcgac gccctggaag aaaaactggc gcagcttgag ttccgccgta tgttctctgg
    43561 cgaatatgac agcgccgact gctacctcga tattcaggcg gggtctggcg gtacggaagc
    43621 acaggactgg gcgagcatgc ttgagcgtat gtatttgcgc tgggcagaat cgcgtggttt
    43681 caaaactgaa atcatcgaag agtcggaagg tgaagtggcg ggtattaaat ccgtgacgat
    43741 caaaatctcc ggcgattacg cttacggctg gctgcgtaca gaaactggcg ttcaccgcct
    43801 ggtgcgtaag agcccgtttg actccggcgg tcgtcgccac acgtcgttca gctccgcgtt
    43861 tgtttatccg gaagttgatg atgatattga tatcgaaatc aacccggcgg atctgcgcat
    43921 tgacgtttat cgcgcgtccg gcgcgggcgg tcagcacgtt aaccgtaccg aatctgcggt
    43981 gcgtattacc cacatcccga ccgggatcgt gacccagtgc cagaacgacc gttcccagca
    44041 caagaacaaa gaccaggcca tgaagcagat gaaagcgaag ctttatgaac tggagatgca
    44101 gaagaaaaat gccgagaaac aggcgatgga agataacaaa tccgacatcg gctggggcag
    44161 ccagattcgt tcttatgtcc ttgatgactc ccgcattaaa gatctgcgca ccggggtaga
    44221 aacccgcaac acgcaggccg tgctggacgg cagcctggat caatttatcg aagcaagttt
    44281 gaaagcaggg ttatgaggaa ccaacatgtc tgaacaacac gcacagggcg ctgacgcggt
    44341 agtcgatctt aacaatgaac tgaaaacgcg tcgtgagaag ctggcgaacc tgcgtgagca
    44401 gggaattgcc ttcccgaacg atttccgtcg cgatcatacc tctgaccaat tgcacgcaga
    44461 attcgacggt aaagagaacg aagaactgga agcgctgaac atcgaagtcg ccgttgctgg
    44521 ccgcatgatg acccgccgta ttatgggtaa agcctctttt gttaccctgc aggacgttgg
    44581 cggtcgtatt cagctgtacg ttgcccgtga cgatcttccg gaaggcgttt acaacgagca
    44641 gttcaaaaaa tgggatctcg gcgacatcct cggcgcgaaa ggtaaactgt tcaaaaccaa
    44701 aaccggcgaa ctgtctatcc actgcaccga gctgcgtctg ctgaccaaag cactgcgtcc
    44761 gctgccggac aaattccacg gcttgcagga tcaggaagcg cgctatcgtc agcgttatct
    44821 ggatctcatc tctaacgatg aatcccgcaa cacctttaaa gtgcgttcgc agatcctctc
    44881 tggcattcgc cagttcatgg taaatcgcgg ctttatggaa gttgaaacgc cgatgatgca
    44941 ggtgatccca ggcggtgcgg ctgcgcgtcc gtttatcacc catcataacg cgctggatct
    45001 tgacatgtac ctgcgtatcg cgccggaact gtacctcaag cgtctggtgg tcggtggctt
    45061 cgagcgtgta ttcgaaatca accgtaactt ccgtaacgaa ggtatttccg tacgtcataa
    45121 cccagagttc accatgatgg aactctatat ggcttacgca gattacaaag atctgatcga
    45181 gctgaccgaa tcgctgttcc gtactctggc acaggatatt ctcggtaaga cggaagtgac
    45241 ctacggcgac gtgacgctgg acttcggtaa accgttcgaa aaactgacca tgcgtgaagc
    45301 gatcaagaaa tatcgcccgg aaaccgacat ggcggatctg gacaacttcg actctgcaaa
    45361 agcgattgct gaatctatcg gcatccacgt tgagaagagc tggggtctgg gccgtatcgt
    45421 taccgagatc ttcgaagaag tggcagaagc acatctgatt cagccgacct tcattactga
    45481 atatccggca gaagtttctc cgctggcgcg tcgtaacgac gttaacccgg aaatcacaga
    45541 ccgctttgag ttcttcattg gtggtcgtga aatcggtaac ggctttagcg agctgaatga
    45601 cgcggaagat caggcgcagc gcttcctgga tcaggttgcc gcgaaagacg caggtgacga
    45661 cgaagcgatg ttctacgacg aagattacgt caccgcactg gaacacggct taccgccgac
    45721 agcaggtctg ggaattggta tcgaccgtat ggtaatgctg ttcaccaaca gccataccat
    45781 ccgcgacgtt attctgttcc cggcgatgcg tccagtaaaa taagcattac gttatgctca
    45841 taaccccggc aaatgtcggg gttttttaat tgtgctgcgc gaaagcagac aacaattttc
    45901 ttgcttcact attggctgcc tgcattacca tccacggact gaacgcccac ggcgtggcat
    45961 caataccgtg taatacatct gctaaatcac accattgata atccatcact tcatcatcgt
    46021 tgatctgtaa cgcactgttg gtgcgtgcgg caaataccgg acacacttca ttttccacaa
    46081 tgccattcgg atcggtggcg cgatagcgaa agtcaggata gatagattca ggaggcgtaa
    46141 tttccacgcc aagctcataa cggcaacggc ggatcactgc gtcttcgttg ctttctccca
    46201 gttgtgggtg cccacaaacc gagttagtcc acacgccagg ccatgctttt ttgctcagtg
    46261 cgcggcgggt aactaataat tgccccttgg cattaaacag ccaactggag aacgcgagat
    46321 gtaagagggt gtctgccgtg tgtgcggcat acttttccag cgtacccgtg ggaactccct
    46381 gtgcattcaa taaaatgacg tgttccgttt gcataatttc tcacatgtaa ttctgatcac
    46441 tcatcattat agataattga agagtgaaat gattaaccaa gtgagcgttt atcgacaacc
    46501 gcccgttttg agcggatgcc gacaggtaaa aaccatttaa aaaagtagca tcatatattt
    46561 gaagcgactt tcaatggcca ttgcaacaca gtcagaaatg acaggaatag agagagtaaa
    46621 aagcaacaac agactgaata tagcgcgcat taaaaaattc atattattct ccatgctcat
    46681 ttttcttcag cttgcgcatc agaagccaca tacgtactgt cctgactttt aaatctttat
    46741 cagagacgga ttccttcacc aggtcagcat gatgctgata gccattaaag aagacgttca
    46801 gcacaacggc gctaagggtt gcgagcataa tgccgctatg tagcagcggt tgcagtacgg
    46861 ccggtaactt agaaaagaaa tcgtgagaga gcgtcggagt catgccaacg ccgagactga
    46921 tcgccacaat atagaggttg taacggttgg tggtgtagtt acagcgcgac agaattcgaa
    46981 tccctgtcgc cagtaccatg ccgaacatca ctagaccagc gccgcccagc acaaattgcg
    47041 gaatggaggc taccagcacc gccatttttg gcaccatgcc aaacaggatt aatataattc
    47101 ccgaagaaat acacacccag cggctatgaa cgcgcgtcac gctaaccagg ccaacgtttt
    47161 gagaaaatga cgtgtggggg aagctgttaa acgtgccgcc tatcattgtc cctacgccat
    47221 cgacacgcag cccgcgaata atatcgtgcg aagagagttt acgaccgact atttcaccca
    47281 gtgccaggaa catccccatc gactcgataa acacgatgat taacacggca gtcatggtca
    47341 gaatggaaac gggatcgaaa atcggcatac caaacgacat cggcgtaaca atcgcaaacc
    47401 atgaagcatc atgtagcccg gataaattga cttcattcat catccacgaa agtaaaaagc
    47461 caaatacaat ccccagtaat acggcgacgt tggacataaa tcctttcgca tagcgagtaa
    47521 tgaacaagat aaaaattaag acggcaaagg agatacctaa ataaacggga ttaccatatt
    47581 gcggattccc tttacctccg gcggcccagt caatacccac ctgaatgatg ctaagcccga
    47641 tagaagtaat aaccacaccg gtaaccagtg gcgggaataa aggcatcaag cgaccgataa
    47701 gtggcgctaa taatgtggtg ataaaacccg cggcgatagt ggcaccaaat atccccagca
    47761 ggccgatatc cgggttcatc ccaatggcta tcattggtgt tacagcagca aaggtcaccg
    47821 acataatcac cggcaggcgg atccccataa agcggccgat accgatacat tgcaataatg
    47881 tgacgatccc gcagcaaaag agatccgagc taatgagcat cgcaatagct tcttttgaga
    47941 ggcccagtcg gtcaccaatc ataagaggaa cagcgactgc acctgcgtac atgacaagga
    48001 cgtgttgcag accgagtatg atcagctttc ctggtgataa tatgcggtca acctcatcag
    48061 ttgggcggtc ttgcccagaa gatgagggaa gttgggaatc tatggcgctc atcagtgttt
    48121 ctcctttcgc ccgccagagt aaaaagcaac cgtttacgtt aatgaaactg tctaaacaca
    48181 tgctcgtgga gtgccagttt ttgcgaggaa ggggagttag agacaggaat tgcggaggca
    48241 atcacataat cgtggttaaa ccacgaaaat gagaagagaa cctgacaatg gaattatctg
    48301 taattttctc atattgatat ttcattaatc attctggcat gtcgcactct cgcatttaat
    48361 cgtttttatc tggatagcgc tcttttgatc ggcaatgttg aaataatgaa agcggcatag
    48421 attgaggggc aataatttga actcagtcgc aaaattataa ttaaaacggt catgctacct
    48481 aatatatgcc cgtttattgc atcgcgaaat ttgagaagac ataactcatt aaatgaaagg
    48541 gatgcaaatg aataagttta ttgctgctga agctgcggaa tgtataggct gtcatgcttg
    48601 tgaaattgcc tgtgcggtgg cacacaatca agaaaactgg ccgctgagtc acagtgactt
    48661 tcgaccgcgt atccacgttg tagggaaagg ccaggctgcg aatccggtgg cctgccatca
    48721 ctgcaacaat gccccttgcg ttacggcttg tccggttaat gctctgactt tccagtccga
    48781 tagcgtacaa ctggacgagc aaaaatgtat tggttgtaaa agatgcgcaa tcgcttgccc
    48841 ctttggcgtc gttgagatgg tcgatacgat tgcgcagaaa tgcgaccttt gtaaccagcg
    48901 cagttccggc acgcaagcct gtattgaagt ttgcccaaca caggcgttac gactgatgga
    48961 cgataaaggg ttgcagcaga taaaggtggc ccgccagcgc aaaacggcag caggaaaagc
    49021 gtcatcagac gctcagccat ctcgcagtgc agcgttgctc cccgttaact cgcgtaaagg
    49081 cgcagataaa atttcagcga gtgaacggaa aacccacttt ggcgaaatat attgcgggct
    49141 ggatccacaa caagcgactt atgagagtga ccgctgtgtt tattgtgccg aaaaagctaa
    49201 ctgcaactgg cattgcccgc tgcataacgc tattccggat tacatccgtc tggtacagga
    49261 aggaaagatt attgaagcgg cagaactttg ccaccagacc agttccttac cagaaatttg
    49321 cggcagggta tgtccacagg accgtctttg tgaaggcgca tgtactttga aagatcactc
    49381 gggcgcagtc tctatcggta atctggaacg ctacatcacc gataccgcgc tggcgatggg
    49441 ctggcgtccc gatgtcagca aagttgttcc ccgtagcgaa aaagtggcgg tgattggcgc
    49501 tgggcctgca gggttagggt gtgctgatat tctggcgcgc gcaggagttc aggtcgatgt
    49561 ctttgatcgc catccagaaa ttggcggtat gctgactttt ggcattcctc ctttcaaact
    49621 cgataaaacg gtattaagcc agcggcgaga gatattcacc gcaatgggaa tcgactttca
    49681 tcttaactgt gaaattggcc gcgatattac ctttagcgat ttaacttctg aatatgatgc
    49741 agttttcatc ggcgtgggga cttacgggat gatgcgagca gatctgccgc atgaagatgc
    49801 gcccggtgtc attcaggctc taccgttcct gactgcccat acccgccagc tcatgggatt
    49861 gccggagtct gaagagtatc cgctgacgga cgtggaaggt aagcgagtcg tggtattggg
    49921 cggtggcgat acgacaatgg attgtttgcg gacttccatc cgcctcaatg ccgccagcgt
    49981 gacctgcgcg tatcgtcgtg atgaagtcag tatgccgggc tcgcgcaaag aggtggttaa
    50041 tgcgcgcgag gaaggtgtcg agtttcagtt caatgttcaa ccgcaatata tcgcttgtga
    50101 cgaagatggg cgtttaactg cggtgggcct gattcgtacc gccatgggtg agccggggcc
    50161 ggatggtcgc cgtcgtcctc gtccggtagc gggttcagag tttgaattgc ccgccgatgt
    50221 tctgattatg gcctttggtt tccaggcgca tgccatgccg tggttgcagg gcagcggaat
    50281 taaactcgat aaatggggcc tgattcaaac cggtgacgtc gggtatttac ctacccagac
    50341 gcatctgaaa aaagtctttg ctggtggtga tgcagttcat ggcgcggatc tggttgtcac
    50401 tgcaatggcc gcaggaaggc aggcggcgcg cgatatgtta actctgtttg atacgaaggc
    50461 atcgtgatga aatcgttaat tatcgttaat ccggctgact gtattggctg ccgtacttgt
    50521 gaagtagcct gtgtggtcgc tcacccttca gaacaggagt tgaatgccga tgtcttttta
    50581 ccccggctga aggtacagcg actggacagc atcagtgcgc cggtgatgtg ccatcagtgt
    50641 gaaaacgccc cttgtgttgg cgcttgcccc gtgggggcgc tgacgatggg cgagcaggtg
    50701 gtgcagacca attctgcccg ttgtattggc tgtcagagtt gcgtcagtgc gtgcccgttt
    50761 ggaatgatca ccattcagtc gttgccgggg gatacccgac aacaaattgt gaaatgcgat
    50821 ctctgtgaac agcgggaaga ggggccagcc tgcgttgaat cttgcccaac acaggcgctg
    50881 cagttgctta ctgaaagaga actcaggcga gtccgccagc agcgtattgt tgccagcggt
    50941 gagaatcctc tctgaaagaa atctccgcgc tgaaaggcgc ggagaatcta ttagattgcc
    51001 caaccacccg cgtaaaatgc gaccagtgcg gcagtaatga tcaccgtacc aatattcagc
    51061 ttttgccatt cgcgtgcaaa gacgcggcct acgaccagtg tcacaaagcc cagcataata
    51121 ccggtaacga tattacaagt cagaacgatg aacacggcac acaccaggcc agccatagcg
    51181 tcaataaaat cattgaaatc cagcttcgag acgttactta acatcagcaa acctacgtac
    51241 atcagagcgg gtgcagtggc gtaaccaggg atcaaaaatg acagcggtga taaaaacaga
    51301 attaacagga ataacgcccc cactacggtt gcggttaaac ctgttttacc cccggcggcg
    51361 gttcctgccg ctgattcgat ataaaccgct gcgggcgctg cgcccaccag gccggagaat
    51421 attgaactta ctgagtcact ggtcagggct ttgccgccgt tgatgatctg gttgtcttta
    51481 tccaacaaat tcgcctgacc ggcgacggca cggatggtgc cagtagcgtc gaacactgcg
    51541 gtcatcacca atgccagtac actcggaagt acagttggct ggagtgcacc cataatatcg
    51601 aggctgaaaa tcagagactt accatcttcg ccagtcaggc ttggcatcgc caccagaccg
    51661 tggtatttca ccgctgggtc aaagattaag ccgatgatcg aaattgcaat aatcaccaac
    51721 aagatcccgc cgggtacgcg acacttctcc aggccgaaga tgaccgccag ccccagcaag
    51781 ctcatcatca ccgggaagga ggtaaacgca ccgagcgcca ctggcaagcc ttcaatcggg
    51841 tttttgataa ccatacccac accgttagca gcaatcagca gcagaaacag cccgataccg
    51901 atacctgtac cgtgagcgat acccatcggc aaattacgta agatccaggt acgcacaccg
    51961 gttacggaaa tggcggtgaa gatgacgccc atcagaaata ccgcgcccag tgcgacagga
    52021 acgctaattt gttgcccgag taccagactg aatgcggtaa acgccgtcaa ggaaatcgcg
    52081 caaccaatcg ccattggcaa attagcccat aatcccatca gcaacgagcc gaagcccgcg
    52141 accagacagg tggcaacaaa cacagctgcg ggaggaaaac ctgctttgcc cagcattccc
    52201 ggaacgacga taacggaata aaccatggcc agaaaggtcg ttaagccagc cagtacttcc
    52261 tgacgaacgg tactgccacg agcggtaatt ttaaaataat tatccagcgc gccctgtggc
    52321 tttggtgcgt ccggtgtttg taggatgtct ccagacataa tgatgtcctc acgaggatgt
    52381 taaagtttta ttattagttg cgttcgtaca ccagacgacc atcaacgtag gtgcggtaga
    52441 tcgaacggtc atcgcccaac gtcatcatca cgaacaattt gtcgactaaa gaaacagagt
    52501 tgtcatagcg cagctgctgt agcggagtgg cggtgggttc catcaccacg aaatcagcct
    52561 ctttgccagg taaaaagttg ccaatcaaat cgtcaaggcc cagagatttc gctccgccga
    52621 gcgtggccag gtaaaacgct tcatatgccg agaggcgata gccttgtaat tgcaatactt
    52681 tgtaggcttc gttcagcgtt tgcagcatgt tgaaagtggt tccggcaccg atatccgttc
    52741 ccatgcccac tttaactttc ttctgccatg cttttttcaa gttgaataag ccgctgccga
    52801 ggtaaaggtt ggaggtcgga cagaaagcaa tgctggattt ggtttcgctg agacgatccc
    52861 actctttttc ttcgagatgg acgcagtgag caaagacaca gtttttaccg gtcaggccgt
    52921 actgatggta aacatccaga taaccatcat ggtcaggata aagcgatttc acccaggcaa
    52981 tttcatcttt gttttcacag agatgggtat gtacccacgt atccggatat tcttctttca
    53041 ggcgttgcgc catcgccatc tgttcaggag atgaggtcgg ggcgaagcgt ggcgtaatcg
    53101 catatagcag acgaccattt ttgtgccagc gttcgatcag ttctttgctt tggtgatagc
    53161 tgctttcggc agtgtcgagc agataatccg gtgcgttgcg gtccatcatc accttaccgg
    53221 caatcatacg catattgata tgactggcgg cttcaaacag cgcatcaaca gattgcggat
    53281 gaacagtgcc aaacaccagc gccgtggtgg ttccgttacg taaaagctgc ttgatgaaga
    53341 acgccgacat ttcgcgggcg tactctaaat cctcataacg acgttcagta gggaaggtgt
    53401 gtttattcaa ccactccagc aattgctcac cataggcccc caccatttca ctttgcggat
    53461 aatggatatg tgtatcgaca aagcccggta ctatcagttt gccgcgatag tcgcgcacgc
    53521 gaatggtgtc aggaatttga tgctttccgt tttcccattc gccaaaccat tccacttttc
    53581 cctgtttaat gagtaataaa ccatcctcaa taaaccgcag cgcagaggca atctcttccg
    53641 ggttatcgat cgtacgggtg acatcaataa aactgcctcg taccgctttt aacgtgtgtt
    53701 ctcctgacat cattgactcc tttactgtta atccatctct tccgctgagg taataccagg
    53761 cagaacgttt tcctgtcggt agccaccagg gaggataata tttaataaaa tcgcagttaa
    53821 cccgccagca caaatagggt tttcaactaa tacataaata gaggctggca atattttaaa
    53881 aatttcggga tcgtaggaga cgccaagccc taaacctaaa gaagtggcga caataagtgt
    53941 ttcacggcgc tttaaaccgt tggtgatgat gatgcgaatc cctgcgatgg caatcatgga
    54001 aaacatcaac gtcattgcgc ctcccagaac tgccgaggga atggtcgtga agaagccgcc
    54061 aatcatcgga aataagccga ggataaccag cattaccgcg atggttcgcc cgacataacg
    54121 tgaagcgacg ccagtcatct gaataacccc attattttgc gcaaacgtgg ttaatggtaa
    54181 tgaaccgaca gcggaggcga taacagaaac cagaccatct gccagcacgc cgcctttcag
    54241 ccgggactga tactcttccc cctgaatggg gcggcgggaa accattgccg tggcggtgat
    54301 atcgccgact gcttccagca cgctaagcag ataaatcgtg ccaaccacca ggaactgatg
    54361 gaagctaaaa ctaaagccgt atttgaacgg atgcgggatg gtgattaacg gcaaattgcg
    54421 catactgctg aaatccacca tgcccaggca taacgatgcg atatagccga cacatagccc
    54481 aatggcgatc cctcccatgc gtagcaacgg actgcgacag cagttaaagc cgatcaccac
    54541 aattaaaacc aataaaccaa cgccgagatg ttcgtaattg ccgaacgtac cgctgctttt
    54601 ggctgcaaat cctccaccaa aatcgataat gccgacttta atcaggctta agccgatcat
    54661 cagtaccaca ataccgctga cggtaggcgt aataacccga cgtaaatagg gcaagataaa
    54721 tgaagatccg acaaccagaa atgcgccaac gaaggagacg ccgagaagcg acgacatgat
    54781 taactcttcg tgaaaaccgt cgcttttcat gctgctgccc agcgcaatca tgaccgtaac
    54841 aaatgaaaaa ttgactgact gaattgagag taggccagaa ccgacgatgc cgtagcggtt
    54901 tacttgtaac caggtaccaa taccagaggc gatcatcgcc atagaaacaa gataggcagt
    54961 tgtttcagcg gaaagctgta aggccgcacc cacgattaac gcgggggtta ccatcggaac
    55021 gaaaattgcc aacagatggg taatggcacc aacgagagcc tgatgaaagg gagggcgatc
    55081 ctccagttca aatataaggt cagaacctgc atggtttata tcagacatcc cttcactcct
    55141 tttaaagtaa atttgatcat ctgaattagt aaaataaatt cccacgaatt tggggcgcag
    55201 gacgccttga gaacggctta tctcattttc gcagtcacta tttagtcatc gttcaaacag
    55261 agaaacaggc cgccgaagcg gccatttatt atttatattt tttccagcgc agtgagtatt
    55321 ttctccggtg tgaaatgcca ttcgcgtaac cagatgccgc atgcatcgtg aattgcggta
    55381 gcaatcgccg gagctgcgcc atttacaccg atttccgaga tcgatttcgc cccgaacggg
    55441 ccgactttat cgtcgctcgg caccagcaca gcgcggaaat cacgcggaat gtcaccaatt
    55501 ttcggtgcgc cgtaactgcg taaatcacgc gttaacgggt gaccttcggc gtcataaatg
    55561 atctcttcgc tcatactgtg gccgatagca cgcagggtgg caccgtagat ttgtcccaac
    55621 gctaactctg gattgaccgg tgtaccgcag tccagcaagg cgtagaattt atccaggcgg
    55681 atttcacccg tacgcgtgtt gacggcaact tcagcgaagt ttgcgccata cgggaaggcg
    55741 aaatcaggcg tgatataact gccagttccc accagtgaac caaagccggt gccggtttcg
    55801 cctttatggg caatatcccc gaaactaact tcgcctttct tgccgcgcac gacgcccggc
    55861 gttgccagtt gaacatctgc cactggctca cccaacattt gcgcgccgcg gaacagaatt
    55921 ttctcccgta gattttccgc tgccaaacgc gccgcgttac ccgagaagca agtaccggac
    55981 gaggcatatg cgcctttatc aaacaacgca tgatcggtat caccggagat aacatgcacg
    56041 tcctgcggtg ggcagtgcag cacttctgct gccagtttcg tcactacagt atccagacca
    56101 gtaccaatat ccgcaccgcc agaatgaacg ataaaggtgc cgtccgattc cagtttgatc
    56161 atgcagttag cctgatcgat atccgggata cccgatttct gcatgataat ggcgacgccg
    56221 cgaccgatgt gccagtcacc attttgcggt ttcggtgacg accattggat catctcgcga
    56281 ccctgacgca ggatctcttc cagtgcacag ctggcggcgg aaggaacgga ggtcggcgct
    56341 ttaccttcac cgattgcacc gagaattttc agctcttgcc cttcgtgtac ccggttacgt
    56401 tcgataattt ccagttggtc gatctgtaac tgttcagcca gttccgctaa tgccatggtg
    56461 atagcgaagt tacctttcgg tgcgccataa ccctgataag caccatttgg gcaaatgttg
    56521 ctgtagtagg tggtgacctg gaaatcgacg ttatcgcacg gatataacgg cagcgacagc
    56581 gccggtccgt tacacggtac ggtgagtgag tggttgccgt aagggccagt gttggcgcgg
    56641 aaatccatct tcactgccgt caggcgacca tcttttttcg ctcccagttt gacggtgact
    56701 ttcgcgacgt gacgagaggt gttagcaata aactcttctt cacgggtgta gcggaacagt
    56761 accggacgcc cggtcacgca ggttgcccag gcgcacactt cttccagcag gatgtcctgt
    56821 ttggaaccaa aaccgccgcc aactcgctct ttaatgacat gaactttatg ctgtttcatg
    56881 cccacgaggc gcgcgacctg gcggcgtaag tgccatggta cctgggtgga ggcgtggata
    56941 accagacgat cgccgtccat acgagtaaag cagatatgtg tttcagtcgg gcactgctgc
    57001 gcttgcgttg agttataggt tcgctcaatg atcacatcgg catcggcaaa gcctttgtcc
    57061 atatcgccaa tatgaccatg aatactggcg gcgatatttt tgcgagggcg agaaccgatc
    57121 gggaagttga tgatcatatg ctcgccgcgc tgggctgcat ggctgttatc gtcttccaga
    57181 gtatctggcg caccagcaac atacaccacc ggttcatcgt gcacgacagg cgcatcttcc
    57241 gccattgctt cgtcgatcga cattaccggc ttaagcactt catattcaac gtcgatgagc
    57301 ttcagtgctt cgagcgcaat ttcttcactt tctgcgacga ccgcagcaac acgatcgccg
    57361 acgtgacgca ttttcttgcc gaacatacgg cggtcaagcg gtgacggttc cggtgcgctc
    57421 tgaccacccg gggtatagta gatatccggg caattcaggt gagtaataac gtgaacgacg
    57481 cccggtaagg cttcagcttt gctgacatcc agatgagtaa tcagtgcgtg agcgtgtggg
    57541 ctacgtaaca ttttaatgac gcaggcgtca gccgttacgc ggtcttcaac atagcagggt
    57601 ttcgcctgca ccattttcgc ggcatcagtt ttaggataat gcttaccaat gacttctagg
    57661 tcgtcacgga aagtcggagc gatatcaatg gtggcctgcg gattattttt acgtgcaacc
    57721 gccagttcaa tgacctgata gtattgctgc cagccagcat cgcggctgaa caaaccagaa
    57781 agcgcgtcgt cgatctcttc gcgggtaggt gcggcgatgc gatcgagaag atcggtgata
    57841 atcagagctg cagctggatc gttataacca gactgcacca cgccaacatc aaccattgcc
    57901 tgttgaacca gacttaactc gttccatttg cccagagatt ctgcggtacg aatatctgcc
    57961 ttctctaact gtgcggcaat aagcaaggac gcgttaacga tattaccgtt aaagattatt
    58021 gcgtcagaac cggcaaaccc gaaaccatca tcactgttgc gtacagagtg cattcccatg
    58081 ttaaacaaca gcttttgcac gttttcgcct ggattaacgg ttagctcctg aggcgcgcca
    58141 tttaaagtaa agtggatgat catacggctt cctccccagc ctgttggcag tcggcataca
    58201 ggtcggctac cagaactccc gtgatatagc gtttataggc cacgctgccc cgcaaatctt
    58261 cctgcgggaa aatggcgttg gcgacagcct gttcaagtgc attgccttcc agattttgtt
    58321 tttcgacatc atgcagacgc agtgctttac tggcgacgcc atccagcgca attcgcatac
    58381 cgtcgtggtc tgtcattgca acggctgccg tcacgacggt taaacctgcc tgagaacggc
    58441 taattttgcg ggtcgcacag gtgcgatacg gatctttaat gataatttcg gttagcaggc
    58501 gatcgcatgg gcaggccagg tagtcctcga ttgacagcgt ttcgccgttg ccaaaaacca
    58561 gttcagcatc cagtgccaac aggacgggaa gcagcaccga ctcttcctgg cgggcggcga
    58621 tttcaccacc aatggtcgac tgattacgaa catggcgtga gtaaacaaaa ccgagggctt
    58681 cacgcagcgc tgcaggaata aatcgcgcat cacgcagtgg ctgcaagcga gacattgcgc
    58741 caatccgcag tgcaccgtta tcccagtcaa cccagtccag ttccagatcc tgtaaggaaa
    58801 tggcaatctt tttatcggta cgggttggtg tagcattgag tttgctgccc ccggcgaacc
    58861 agacggcttc atcctggtag cggcgcttca gttccagcgc ctgttcgaca gagtcgggcc
    58921 tgaaaaattg ttcaatcatc ttctttcctt atttaaccct cttccctgcg ggaagagggc
    58981 atctgtcatt tatgccagcg catccatccg acgccacata ctggcagcgg cttttctggc
    59041 ttgtgcataa atggaatcgc aatcgaagtt aaactgacgg tcttcataga ccatcacacc
    59101 attgaccatc acgctgtgaa cgctgcctga gcccataccg aaagcgatat gcccggcgat
    59161 attgtctgcc agcagcggcg tcggcgagtt gtaatcgcaa atggttaaat cagctttgta
    59221 accggcttcc agaagcccaa atttcgcgcc aaagttgcgg ctcatcagtt cgttaccgtt
    59281 agtcagggct ttggcaaaac tgtcaggcca cagcggacca cccgcatcgc gatgtttaaa
    59341 gaaggcaaat ttcatctctt caaacatgtc cgaaccaatg ccgtccgttc ccaacgccag
    59401 attgcggatg tcgctaaggt gatggttgta gccgacatgg ttgttcatgt ttgaacgggc
    59461 gttatgcacc aggaacgcat cgcgctgatt gagtagggtg atgtcatctt tcgacaagta
    59521 cagcccatga gcgaccagcg ttttgctgtc gatgagatcg aattgcgcca gtcgtgccag
    59581 caggtctttg ccgtaccagt ggtgactgta ggaaacgtcg taaaggtctt ccgcagcgtg
    59641 aatatgcaaa ccacggcctg tggctttcac ggcttcacgc agcatctcca gaccggcatc
    59701 cggcacggta aacggcgcgt gagcaccgat atgtgcttcc accagatacg gctcgcttgt
    59761 cgctttcttc gcctcatcaa tcaaacgggc gaaacggatg ttttcttcta caccttcctg
    59821 caactctttg atgccgttgt tacggtcagt agtttcaaaa caggtcatcg cgcgcaggcc
    59881 aacttttaaa aatgcgtcgc gcaatgtgga gagcgacccg ccgatatacg ccggagaggc
    59941 atggtgatcg ataaccgatg tacatccgct cttaatcgct tccagggaac aaatcagtcc
    60001 gctgtaatag agcgactctt catcaagggc gcgatcgagc cgccaccaga gatttttcag
    60061 cgttgagatg aaatccgggc aaggggcgat gtttgccata attccgcggg aaagccccga
    60121 gtaaaaatgg ttgtgcgagc agacaatccc tggcatcaca atccggccat gcatctcttt
    60181 gaagctggcg tcggggtagc gttgcgtcag ggcatcgccg atagcgacaa tcacatcgtt
    60241 ttcgatggcg atatcaacgc cttcctgcac ttttgccggg tgtagctgta ccgcagtgac
    60301 attcttcaga atcaacatga ttacacctcc acgcggccca gcagataatg atgatgctgg
    60361 tggacatggc tgatgatgcg gcacatatcg ttcagctccg gtggtacgtt gttaaactga
    60421 cctttgctgt cgatgtttaa cacccagctt tggttattca gacgtactcg tacccggcaa
    60481 tcttccacaa ggaagcctgg gttgctgctg ttatcaaagt cttgcgccag gctgaagacg
    60541 gtgattttgt ctttgtacgg tttaccgttc cacggacaga actgagcgca gttgccgcat
    60601 tcgttacagt aagcgtcgag gtgcagcgtc tggaaacggt tctggaagcc tgggaccgca
    60661 atggagacgt tggcgcggtt cgggcagaca tccacacact tgctgcaaac gtagttacat
    60721 tcgaggcagc gagcggcttc ctgggcgaca aacgcgtcac gatcgtcact gttcaccagc
    60781 gtgatagaga tatcgccttt acgttgatag atttccgctg gattgacgtt gttccagtat
    60841 ttatcgttct ggtgggaacg gatattttcc cgactaagga tggcatcggt cgcccgacgc
    60901 gcggttccga cagcagcgac aatggaggat ggtccgcgct gtacgtcgcc gatcataaag
    60961 acgtcagtca gacgagtttc gccattatgg tcgacgtctg gccagccgtt tttgtccagc
    61021 ggcacgccca tcgcattcag ggcttcagta tcctgctgtt caccaatggc ggtgatcagg
    61081 ctgtctacaa gcagtgttac tgtttcattg gtttcaaccg gacgacgacg acctttctca
    61141 tccggttcgc caagcgacat aacgcgcaag gttaaggtgc catcagcatc gaaacgttcc
    61201 ggattattca ggaaacggaa ctctacgccg tcgtgcaacg cttcttcata ctcttcgcgc
    61261 catgcgggca tctcttgtag tgaacgacgg taaacgatcg ttgctttttc tacgcctgga
    61321 acgcgtaacg ccgcacgagc gcagtccatt gcggtgttac ccgccccgac aacgaccaca
    61381 tgtttgccca gcttgagcgc tgtacccttg ttgtattcac gcaggaaggg gagtgatttc
    61441 cagacatttt ggttgtcgcc cgccagtttc acaccgctat ttttatcagt gccggtggca
    61501 atcagaacat agtggaagcc ctgatttttt aactgctcaa tggttaaatc gggtgagcag
    61561 ccatactcaa atttcacgcc gtgagcggca acaaaatcga tatcgtgctg aattaactct
    61621 gcaggaatac ggaactgagg aatgatattt ttcaccacgc cgcccgcatt ggcttcgcgt
    61681 tcaaacagcg taaccggatg gcccgctctg gcaaggaagt aacctgctgc cagacccgcc
    61741 ggacctgcac caatcacggc aaccggatgg cgtgaaccag aaccggctgg tttgtgccag
    61801 cgttgcttat attcatccca acctttttcc agcgcgactt ttttcagttc gcggatattc
    61861 agcgcactgt cgtaatccag gcgggtacag ttgtattggc actggtgatc gcaaatatga
    61921 ccggtaatgg cgggcagagc gttgcgttgg tagatgagtt ccagcgcgtc ggcatagcgg
    61981 tgttcgccaa gcagacggat gtattccgga atatcttgct tgatagcgca ggcagtaaca
    62041 cagggggcaa cgtagcagtc ggtcagcggc aggtcttctg ccacttcaat acgctcttct
    62101 ggcttccagt gtttctgggt gtattccatg gttaacgcat ctgctgccag tctgttcagt
    62161 cgttcgacgt caacatggtc aagtccccag gcgtcggagc cttccagctc gcgcatgcag
    62221 gcacttaagc gcagatagcc gccaggtttc agcaggtcgg ttgccatagt aatagggcga
    62281 atacctgtat caaaaatatc gcggatagtc agctgactgg caccaccgga ataagaaatg
    62341 ggcagtttgc cgtcaaaggc gcgagagaga actgctgcaa cattgatgga gagcgggaac
    62401 agcgcacggc ctgacatata catctcttca ccaggcagtg cgcctttatt gttgatggtg
    62461 ccgagagtgt tagtcagttt tacgccaaag ccgagtgatt tttcttttgc cagtgccatc
    62521 aggcgttcca gcatttccag tgcttgcgtc agcttgaggt cgtgatcaaa tgactcttct
    62581 tttaagccta tgtaaccgaa accgcagaca tcgaggatct cacgaacacg cgcgtacccc
    62641 agtaaggtcg ggttaagttt cacaaaggtg ttgagccctt tttcttccag catgtagcgg
    62701 caaatggctt cgatttcatg cggaggacag ccgtgcatgg tggagagggt gacgccatgc
    62761 accatactgg tggggatgcg agcgggtaag gcttgcaagc tttcgcgttt ttcctgcaat
    62821 ccgtggcgag ctaaaaatgc gtcatcctgg agtaatttat tcagcgtatc gcgatattga
    62881 gcgaatttcg gatggtcaga tgcgtccatc atattgtcga tgaactgttg catcggcggt
    62941 tgcttaatac cttcgaggtt gtaaccgacg ctcatattaa agatgaacga tttaccggaa
    63001 tcagaaggct ggaacatcgc ttcgagaagg tgcagggcaa accaggcttt gaggtattca
    63061 tcccaggctt taagcagggt aaattcggta gaccattcgg tgttaaagca ctcgtcttcg
    63121 gcatcgatac agggcttttc cagctccagg cggtcaagaa tttggacggt ttttagttcg
    63181 atgaagcgtc cgccagtcag ccaggaagtg acaatatttt gcgcgagctg cgtgtgcggg
    63241 ccagcggcag ggccgacggg agtggcacag gtttcaccga agacgctaac agttttacct
    63301 tttacaggtg agtaaaactg ttgctcggga ataccaaaga ttgagcgttg ttgttggtat
    63361 tcatcaaata tgcgcgtcaa aagttcctca aacggaatgg gacgcataat atcccccata
    63421 accctctcct tagcttatac agatatcatt gagtgaccgg tgttgagaaa tccggtggtt
    63481 tagggggata gagcaacaat cgcaccactc ttgccaggtt tggcgggaaa tataaaaaaa
    63541 tgtgaggcgg ctcgaaactt aagggctttt tgtgaatgaa ctcacaggtg ctaaatgaga
    63601 attaaaatca ctcctgaaaa ttattattgc cagcccattt atcaattttt ctcttttctc
    63661 aaaatcagtg attccttatc attatgataa tgagtgccgg aaggattaaa tatttgaacg
    63721 caatcgttta actacgtttt ctaaatttca gtataccttt ccttcgctgt aataaagtcg
    63781 tccggagtat caatatctaa aattatttct gcattttcta tttcgacgga ataatgatct
    63841 cccataagga gtgcctgacg catattggtg acattgggtc gttggattgc ctgcatcagg
    63901 catggttttg acactaaaat cggatggccg gggatgccat tatggagtgg cagtattgcg
    63961 ccatcatttc gtaacgacca gatttttcta aaaatatcga tggtgagggt tggcatgtca
    64021 ccgtgggtga gaaaacaatg ttctgtttgc actgcgggta ctgcggcctt gacggatgtt
    64081 agtaaaccct gcgcataatc tgggttgtga ataatagtga tattgctctg gttcgcataa
    64141 cgttcgtgca gttcattacc acgatagccg gtgactaaaa taattcggct acaaaactgc
    64201 aacgcatttt tgatacttgt atcaagaatt gttccctgtt cccagggtaa catcattttc
    64261 cattgcccca ttcttgatga taatccggca gcggtaatta tacagtcgat ggctgacata
    64321 gtggttccat tatttatagg ggctaataac gcctgataat tgcgttactt cctgatggat
    64381 taagttgggg ataatttatc ccagagaggt cataaagact cgtgaaaagt atagttgacc
    64441 catcggcatt agtcattgat ttaggtgcgc agaaacgtcc cactgtgatt tctgttgttg
    64501 gtgctggggg gaaaaccagc ttgctttttt ggctggcaga actgctccag gctagcggca
    64561 ggcgtgtgtt aatcacgacg acgacacata tgtttatgcc aacgtctcac tggcccgtgg
    64621 ttttctgtcg tgatcccgcc atgcttcctc atgcgtctct tacatccccc atttcatttt
    64681 gttttcacag ctggaaagcg aaccagggaa aagtgcaggg atttacgcca gaagcgattg
    64741 atgcactggt gcaacgacca gagtgtgacg taattctcat tgaagcagat ggctcgcgtg
    64801 gaatgccgtt aaaagcgcct gatgagcacg aaccttgcat acccaaaagc agttgctgcg
    64861 tgattgctgt gatgggagga catactttgg gcgcgaaagt gagcacagaa aatgtccatc
    64921 gctggtcgca gtttgctgat attaccgggt taacacctga tgcaaccttg caactgagcg
    64981 atctcgttgc gctggttcgc caccctcagg gggcgtttaa aaacgtaccg caaggttgtc
    65041 ggcgagtctg gttcattaac cgtttttctc aatgtgagaa tgcgattgca caaagcgagc
    65101 tccttcaacc gctgcaacaa cacgacgtag aggcaatctg gctgggcgat atacaagaac
    65161 atcctgcaat cgcgcgcaga tttgtgaatt agcggcccgg gtattccggg ttactgaaag
    65221 gatatccatt gaggttggta tgaatatttt cacagaggct gcaaaactcg aagagcaaaa
    65281 ttgtccgttt gctatggcgc aaattgttga tagccgaggc tcgactcccc gccattctgc
    65341 acaaatgtta gtgcgcgccg atggttctat cgtcggtaca attggtggcg gaatggttga
    65401 gcggaaggtg attgaagagt cgcttcaggc attgcaggaa cgtaagccgc gattattcca
    65461 tggacgtatg gctcgtaacg gtgcggatgc tgtcgggtca gattgtggag gtgcaatgtc
    65521 agtatttatc agcgtccatg gtatgcgtcc acgtctggtg ttgattggcg cggggcatgt
    65581 caaccgggcg atagcccaga gtgcggcgct attaggattt gatattgccg ttgctgatat
    65641 ttatcgcgaa agcctcaatc ctgaactatt cccaccatca accacgcttc tccatgctga
    65701 gtcgtttggt gcggcagtgg aagcactgga tattcgccct gataattttg tcctgattgc
    65761 cacgaataat caggatcgtg aagccctcga caaactcatt gaacagccca ttgcatggtt
    65821 ggggttgctg gcaagtcgtc gcaaggttca gcttttcctg cgtcaattgc gtgagaaagg
    65881 cgtggctgaa gaacatattg cccgtttaca tgcgcccgtt ggttacaaca taggtgcgga
    65941 aacgccgcag gagatcgcca tcagcgtgct ggcagaaata ttacaggtga aaaataacgc
    66001 gccgggtggg ctgatgatga aaccttctca tccttccgga caccagctgg tggtgattcg
    66061 cggtgcggga gatatcgcca gtggtgtggc gctacgtctg tatcatgcgg gttttaaagt
    66121 gatcatgctg gaagtggaaa aaccgacagt gattcgttgt accgtggcgt ttgcccaggc
    66181 cgtgttcgat ggcgaaatga cggtcgaagg cgtcactgct cgcctggcaa ccagctctgc
    66241 ggaagcgatg aaacttaccg aacgcggatt cattcctgtg atggtagatc ccgcctgttc
    66301 attgcttgat gaactgaaac cgctttgcgt ggtggacgct attctggcga aacagaattt
    66361 gggaacgcgg gcagatatgg caccagtaac aatcgcgctt gggccgggct ttactgctgg
    66421 gaaggattgt catgcggtaa ttgaaacaaa tcgcgggcac tggctcggtc aggtgattta
    66481 ctctggttgt gcgcaggaga ataccggtgt tcctggcaat attatggggc ataccacccg
    66541 acgggtgatc cgtgctcctg ctgcaggcat tatgcgatcc aacgtgaaat taggcgatct
    66601 ggtgaaagag ggcgatgtga ttgcctggat tggtgagcat gaaattaaag caccgttgac
    66661 ggggatggtg cgtggcttgt tgaacgacgg cctggcagtg gttggtggtt ttaaaattgg
    66721 tgatatcgat cctcgtggtg aaaccgctga tttcaccagc gtttctgata aagcccgggc
    66781 gattggcggc ggcgtacttg aggcgttaat gatgttgatg catcagggcg tgaaagcgac
    66841 aaaagaagtg ctggaagtgg cttaaatgaa aatggccgga tggtattacc cacccggcct
    66901 gagactgatg acaaacgcca aattgcctga tgcgctacgc ttatcaggcc tacaagtgca
    66961 ttgcaatcta ttgaatttgc gatgttttgt aggacggata aggcgctcgc gccgcatccg
    67021 gcatcaacaa agcgcactta cttgacaatc tttggccgga tggtattacc cacccggcct
    67081 ttaaattact gacaaatcac tgttcctgtt ttgccttcaa tcccttcttt cgctttgctc
    67141 aatacggtaa tcagtgcttc acgacctgcg cgagagcgag caaacgaggc ggcagcttcc
    67201 actttaggca gcatagaacc tttcgcaaaa tgaccttctt cgataaagcg ttcagcatca
    67261 cttaatgaca ggcgatcgag ccactgttca ttctctttac cgaagttaat ggccactttt
    67321 tctaccgcag tcagaatgat cagcatatcg gcatcaatca tttctgctaa acgggcgctg
    67381 gcccagtctt tatcgataac cgcgctggca ccacgcagat ggttaccttc acgaataaca
    67441 gggataccac caccgccaac ggtgatcacc acctgacctg catctaccag agctttaacc
    67501 gtttcttttt caatgatatc aaccggtttt ggcgaggcaa caacacggcg atagccgcga
    67561 ccagcatctt ctttcagagt gtaaccctgt tttgtcagtt gctctgcttc ttgctcggta
    67621 aagaacgaac cgatcggctt ggtcgggttg aggaatgccg gatcgttagc gtcgacttcg
    67681 acctgagtaa ccagcgttgc tacaggttta ttaatgcccc gagaaagcag ttcttctctt
    67741 aaagcgtttt gtagatcgta accaatataa ccctggctta atgcaacaca gacagacatc
    67801 ggcagcattg gcgagtgcgc ttcagttttt gcggcagctt caaaggcctg gttaatcatg
    67861 cccacctgcg gcccgttacc atgagtgacg ataacttcat gtccctgggc aattaaatca
    67921 acaattgcct gagaagtaat ttttaccgct ttcatttgcc cggccaggtc atcgcccagc
    67981 gcattcccgc ccagggcgag aacaattttc ttactcattt ttcctcactc atcattcttg
    68041 attgtgtata gatccctggc agtggttaga gcacgggagg gacaaacggt ttgcgtcgca
    68101 ggaaacgacc tcgcccggct ttgcctgtaa aggtgccgtc acagaaaatc gtttcaccac
    68161 gggataaggt tctgacaatc gcgccctgac aggtaaaacc ctcccatggc gagtagtcgg
    68221 cgttgtcgtg gagatggcga tgctgaattt gttggctctg acgtgggtcg ataatcacca
    68281 cgtcgccgtc ggaaccgggc gctaataatc ctttttgcgg ccacaggcca aacaacctgg
    68341 cgggcattgc gctggttaat tcaacaaagc gttccggtgt tatacgtccc gtcatcacgc
    68401 cactggaaaa cagtaactgc atgcggtttt ccacaccggg taagccattt gggcagcgac
    68461 tgaaatcgcc tttagaaatt tgcaggcgtt gagccatcga gaaggtgcag tgatcggttg
    68521 ccaccacgtc aatcgcacca tcgctgatgc cacaccacag tttgtcctgc tcgcgtacgt
    68581 tacgcagcgg tgggctaaga atgaacttca tgccatcttc tgtatcgtaa ctgcgttcgt
    68641 ccaacaggag atattgtggg caggtttcaa cccagactgg ctggtgattc gcacgggcaa
    68701 gacgcagata atccagacct aagccgttag acaggtgcac gatatagagc ggggcgttac
    68761 cggcaatttg tgccaggtta atcatgcggg cgatggcttc cgcttcgcat tccagagggc
    68821 gactcaaggc atgatagcgc ggcgcggtta accctgcggc gataaattcc gcccgcttgc
    68881 tggcgatagc cgcatcattt tccgggtgca cggtggtcag cgcgccggat tcatgcaagc
    68941 ggcgtaatgc ctgcaaaacc tcgtcatcgt tgagtttgta ttgataggtt aaatagagtt
    69001 taaaactgct cagtccttcc tcgaccatca tcgggatttc gtcgaggatt gcgtgattaa
    69061 tgtgctggat cacaccgtga aagctgtaat cgatgaccgc tttatgggcg gcataaccac
    69121 gataaacctc cagttgatgg cgtaaccgac agccgtttgg gccaaatccc atatggtcaa
    69181 taatggttgt tgtaccgcca cacgcagctg cgcgggtacc ggtaaaaaaa tcatcacaac
    69241 tgcgcgcgat gccgacatca atattgaaat gcgtatggac atccacgccg ccagggaaaa
    69301 cgtaacagcc agtggcatca atttcttcat acgggagctg cggcgaaata ttgttgccca
    69361 actggcgaac aatcccgctt tcaatcagca aatcctgttt ggcttgtcca tctgcgttaa
    69421 cgacagtgcc gtttttgatc aatacgcgca tagcaaactc caaaaaccct ccggcgaacc
    69481 ggaggggaat aagtgaagag taattactct gttgccagcc agcttaacgg gattgcagcg
    69541 tacatcgcgg cacaggtcac caggtgagat ttccaggttt tttcgttagg tgcatgcgct
    69601 tcaggttctt tacccgggcc aaagccgatc accggaatgc cgtgacggcc catgatagat
    69661 acgccgttag ttgagaaggt ccacttatca acaaccggcg ctttgccaaa cagcccttcg
    69721 taggcattca ccagtgcttt aacggtgaag tgatcttctt ccactttcca ggtcgggaag
    69781 tagcattcgg ttgggtaaac caggccagtc caggacggac ggtcgtagtt gtacatagaa
    69841 acaaccgcgt tagctttctg tactgcaggc agggcgcgga tttcgtccag cgcgccttcc
    69901 caggtttcgc cccaggtcag acgacggtcg attgaaactg cgcagctgtc tgctacagcg
    69961 caacggcttg gggatgtgaa gaagatttca gaaacggtga gggtgccttt gccgaggaat
    70021 tcgtcataac ccagacgttg ggagagttct tgtaattcgc caagaatcgg acccattttg
    70081 aaaatggcgt tatcaccgcg ttctggtgca gaaccgtggc agctaacacc ctgaacatca
    70141 atacgaattt ccatacgacc gcgctgacca cggtatacct ggcagtcggt tggttcggta
    70201 ctgaccacaa attccgggcg aatgccggat tgttcaataa tgtactgcca gcacagaccg
    70261 tcgcagtctt cttcctgcac cgtaccggta accagcaggg tatattcatc ttccagaccg
    70321 aggtctttaa tgattttacc ggcataaacc atagaggcca tgccaccttc ctggtcggaa
    70381 gtaccgcgac caccaatcag ttcatcagtt tccatgcctt cgtacggatc gaagtcccag
    70441 tttttgatgt tgccaatgcc gacggtatcg atatgagcgt ccattgccac cagacgcggg
    70501 ccgtggccga tataaccgag aacgttgccc atcgggtcga tttcaacttt atcgaagccg
    70561 actttttcca tctcttcttt aatacgatgt actacgcgtt tctcgtcgca gctttcactg
    70621 ggaatagcaa ccatgtcgcg caggaagcga gtcatatccg cctggtaatc ttttgctttt
    70681 tcaagaatca gtttgaatgg aatattctta gccattattt ttctccagat tttttactcc
    70741 ccgttttgca gggagcagtt ccaatagggt gattaaggtg ctacagcgtg tttgccttcc
    70801 cagacaactt cgcggtagtg cttcacgtcg gtgtcgcctt cagtgctgat aaccagcacc
    70861 acggcatctt tgttcagcgc cagtttttcc atcaggcttt gacgttgcgg gtgataatga
    70921 accgctgcga gaacgcccaa accgacagcg ccggattcac cggagatgat gcgcgggtcg
    70981 ttgccgtacg gattacccag cacgcgcata cctaatgcgg caacgctgtc ctggcaggag
    71041 atgaattggg tggcgcagtt acgtaggatt tcccagccca gcgggttagg ttcgccacag
    71101 gccaggcctg ccatgatggt ggccatatca ccgccaacgt tgacgatgtc gcctttgacg
    71161 ccggagcgat aaatacagtc agctttgtca ggttcaacaa taatgctgtg cagattttgc
    71221 gggctataga cgtcgaccag ataacccagc acaccaccgg ccattgctcc gacaccggct
    71281 tgcagcagaa cgtgcgtcgg ggttacgccc atttcacgca tttgctcgac ggcttcatct
    71341 gccagggttg cgtagccttg catgatccag gttgggattt tggtgtaacc ttcccatgcc
    71401 gtgtcctgta ccacttccca gccgtgctgc tgcgcgtgtt gcatggtcag gcgaacggta
    71461 tcgtcatagt tcatatccgt gacgatgcac tcggcaccga ggttcagaat ggcgtcaacg
    71521 cgttcctgag cagaaccttt cggcatgtaa atcaccgcat tttgtccgag ttgctgtgct
    71581 gcccacgcca caccgcgccc gtggttgccg tcggtggtgg tcgcgaaagt cattttttcg
    71641 ccgatggcat ttttcaggtg ctcaaatgac agcgtttcga tatcaagatg atatttttca
    71701 cacaataatt gagcgatggc gtacgcaccg ccaagcattt tgaaggcgtt cagaccgaat
    71761 cgttttgatt cgtctttgac gagaattttc ttcacaccaa aaaggtttgc gagatcgtcc
    71821 agcgcacaaa gcggtgttgg gcgataacca gctattttct ggtggaactg gcgcgccagt
    71881 ttggcctggc tttgcgaaaa gagcggtgat gtttcgccgt tgaaaaattt gttatcggcg
    71941 atatcaatct tcaatgagaa aacggacata tcctatcctt ttggcctctg gaaatagagg
    72001 gccgaccagc tgatcggccc gaggggttat ttcacgcgtt cttgcgcttc tttcagcagt
    72061 tgctcgagca gtgcacctgg tttggcgtat ttacgggaca ggatcatcgc ggcgatgata
    72121 taaggcttcc agctggcttc tttgtaggta gcgatacggt atttttcgaa tacgccttca
    72181 gtcacttcac cttctttaca ggatacgccg ctgatatcag ctggcaggca gtgcatgtac
    72241 agggcttcgc catcacgggt cagttccatc atctcttcag tacaatgcca gtctttgtgt
    72301 tgcgcgttct gtgccagaca ctgtttttcc agtgctttta agccttcgtg atcgttcgca
    72361 cgcagcaatt cagtacgctc ttccatcact ttgtaaggtg cccatgactt cggataaacg
    72421 atgtctgcgt ctttgaaggc ttcttccatg ctggtgacct gacggaagct accaccggag
    72481 gctttagcat tgtttttcgc cacttcaacc acatccggga tcaggtcgta gccttccgga
    72541 tgggccaggg tgacatccat accgaagcga gtcatcagac cgatgatgcc ttgtggtaca
    72601 gagagcggtt tgccatagct tggagagtag gcccaggtca tggcgatttt tttacctttc
    72661 aggttttcca gtgaaccaaa gtgttcacgt aaccacgcga ggtcagccat tgactgagtc
    72721 gggtggtcaa tatcgcattg caggttcact aaagccggac gctgtggcag tacaccctgc
    72781 ttgtaaccgt catcaagtgc agcgccaact tcacgcatat aggcgttgcc tgcgcccaga
    72841 tacatatcgt cgcgaatacc aatagcgtcg gcgcagaagg agatcatatt ggcggtttca
    72901 cgcacggttt cgccgtgagc gatttgtgat ttgccttcgt cgagatcttg ttgtgcaagg
    72961 ccgagcaggt taagcgcgga agcataagag aagcgggtac gggtggagtt gtcgcggaat
    73021 acggaaatac ctaatccact attaaagact ttggttgaga tgttttcagc acgcagtgct
    73081 tttaatgctg cggcaacgtc cagtacttgt ttcagttcat ctggcgtctg ttcccacgtt
    73141 aacaaaaaat ctttctcgtg aaggtgagag gtcagcgaat tgatatcctt aatcagctca
    73201 ttaacagttt tcatcataaa gtcccggtag tggaatgaca ggcaaagtgg tttatttcac
    73261 tgtgacttgc caaagtgatt ggtgttttca cagctatacc tgggactaac aataagtgtg
    73321 ccagaattat ccgcgcggct gcaaaagact aatttgacgg ataatgtgtg gggttgatca
    73381 caaattgatg ccagcttctg gttgtttgta aaatacgaaa acgtttggct ttttttatcg
    73441 cgttatttat ttgctgctaa gtatcagaaa taagataaag gggcaggcta tctctcttca
    73501 gtttgataaa ctcaccgccg taattctcat attgatatag aaatgtgata tctcttccat
    73561 aatttcatta gaaaatgata aaaatcttat gtttttatca aagccaattt cgcctgagtt
    73621 aatatcatca tgatctgtga accatcaacg tcttcaatga tcgactttta agtaagtctg
    73681 gaaggtaaag ctatggagct tgctactacg cagtcagtat tgatgcaaat tcaaccgaca
    73741 attcagcgtt ttgccagaat gcttgccagc gttttgcagc ttgaggttga gatcgttgat
    73801 gaaaacttgt gtcgcgttgc cggaacgggc gcgtatggga agtttcttgg tcgccagttg
    73861 agcggcaact cacgcctgct ccgccacgtc ctggaaacga aaactgaaaa agttgtgaca
    73921 cagtctcgct tcgatcccct ttgcgaaggt tgcgatagta aagaaaattg ccgcgaaaaa
    73981 gcatttctgg gtacgcctgt cattttacag gatcgttgtg ttggggtgat aagtttgatt
    74041 gccgttaccc acgagcaaca agagcatatc agtgataatt tacgcgaatt ttctgattat
    74101 gttcgccata tatccaccat ttttgtttcg aaacttctgg aggatcaggg gccaggagat
    74161 aacatcagta aaatatttgc gaccatgatc gataatatgg atcagggcgt attagttgta
    74221 gatgatgaaa atcgggttca gtttgttaat cagactgcct taaaaacact tggtgttgtg
    74281 caaaataata ttattgggaa acctatccgt ttcagaccat taacatttga gagtaatttt
    74341 acccatggac atatgcagca tattgtttca tgggacgata aaagtgaatt aatcattggt
    74401 caattgcata acattcaggg ccgacaatta tttttaatgg cgtttcacca atcgcatacc
    74461 agtttttctg tagcaaatgc acctgatgaa ccgcatattg aacaattggt tggcgagtgc
    74521 cgtgttatgc ggcaattaaa acgactcatt agccgtattg cacccagccc atccagcgtt
    74581 atggtggttg gtgaaagcgg cacgggtaaa gaagtcgtcg cccgtgcaat ccataagttg
    74641 agcggaagac ggaataaacc ctttattgct atcaactgtg ccgcgattcc ggagcagctt
    74701 ctggagagcg aactgttcgg ttatgttaaa ggtgcattta ctggcgcttc tgccaacggt
    74761 aaaacagggt tgattcaggc ggcgaatacg ggcacgctgt ttctcgatga aataggtgat
    74821 atgccattaa tgttgcaggc taaattactg cgcgctattg aggcacgtga aattctgccg
    74881 attggtgcca gtagcccaat acaagtcgac attcgcatca tttctgcaac taatcagaat
    74941 ttggcccagt tcattgccga aggtaaattc cgcgaagatc tcttctaccg acttaatgtt
    75001 atcccgataa ctctgccacc gctgcgtgaa cgtcaggaag atattgaact attggtgcat
    75061 tactttttac atctgcatac ccgtcgtctg ggatcggttt atcctggcat tgctcccgat
    75121 gtcgtcgaaa tattgcgtaa gcatcgttgg cccggaaacc tgcgcgagtt aagcaatttg
    75181 atggaatatc tggttaacgt ggttccttca ggtgaagtta tcgacagcac gctattgccg
    75241 ccaaatctgc tgaataatgg cacaacggag caaagtgatg taacagaggt cagtgaggcg
    75301 cacctgtcac tcgatgatgc gggcggcacg gcgctggagg agatggaaaa gcaaatgatc
    75361 cgcgaggcgc tttcacgtca taacagcaag aagcaagttg ctgatgaact gggcatcggc
    75421 attgctacgc tctatcgcaa gattaagaaa tatgagttgt taaacacata acctcagtga
    75481 atccggcctg aattcaggcc ggatatcctt ttacttcgtt ttctcgcaat ccagaactgt
    75541 atttacaatc atctgatacc ccgtgcagcg acaaagattt cccgccagtc cgcgacgaat
    75601 ttccgtaatg gttaatggct tctcgcgtgg tttcgccagc attgccgtgg tagccataat
    75661 caggccaggc gtacaaaacc cgcactgcac tgcgccggat ttcgcataag cctgctgaac
    75721 atgagaaagt tttccgcctt tcgcttcacc ttccagcgtg cggatctctt ttccttcagc
    75781 ccaggcggca aggtataagc aactgtctat tgctgtgccg tcgaccaaca ccgtacaggc
    75841 accacattca cccacgcagc acccttgttt gacacttagc agtccttgtt cgcggagtaa
    75901 ttccgagagc ggcgtgcctg gtgcggcgtg aagctgaaaa ggcatcccgt taatggtgca
    75961 ttcgatggta attgtttcgc tgtgattcat tgcaattttc cccccgccgc ggcgacggct
    76021 tcgctaatca cttttttggt catcgtctgg atgagatgca gacgaaactc tttactggcc
    76081 cgccatgaag aacgcggggc gacatcttgc aggacagatt cgctgatagc ttccagcgtt
    76141 tgcaggttta atggcgcatt ttgtgcagtc tgttcggcat gttggcagcg aatcggcgtt
    76201 ggcgcggcaa caccaaatgc caggcgtaat tcgctgaaat tgccgttatc cagtcggcaa
    76261 tgtgcggcgc agccaatcgt tgaaatatcc attgcgtcgc gcatggcata tttaaaatgc
    76321 gcgctgcccg cgtgttcttt cggctgtggc ggaaaatgaa aggcgacgag gatttcgtca
    76381 tgctcaagag acactttgcc cggcccggtg tgaaagccat taatcgggac gaaacgaaca
    76441 ccgcgcgggg agtggatctc cagtttcgcg tcataaatta gcgttggcgt ggcagaatct
    76501 gcgctggtgg caccgttgca aatatttcca ccgtaggtag cgacgttacg gatctgcggt
    76561 ccagcaatgg acgtggccgc agcacataac gccgggagat gacgttgagt tataggatct
    76621 tctattagct gggtaaatgt cgttgcagag ccgatacgta gcgagccatc ttccgccagc
    76681 gtaattcccc gcagctccgc cagattatga atatcaacaa tatggcgata acggtcattg
    76741 tgatggtgga gctgaatcag tacgtcagtg ccaccggcga gcagtttggc ctgcgggttg
    76801 tcagccagca ggttgatggc atcggcaagg gttgctgcgc gatggtaaga agcaaaatca
    76861 aacatgatgt tatcctcaaa tcaatcctgc cagatggaac tcttcatata accgttttgg
    76921 cgtcagcggc agtgtattga ttgcaacacc ggtagccatc ttcaccgcgt tacgaatagc
    76981 agcggcaaca ggaattattg gtggctcacc cagtgactta tgtccgtatg cggattgcgg
    77041 ctcattgatt tcgacgaacg cgctttccag ttgtggcaga tccggcatgg tcggcatttt
    77101 gtaatccagc agattggggt tacggaccac gccgctttta gcatcgatga tcatctcttc
    77161 aaatagcgcc cagccaatgc ccattcccat tccgccgtgt acctgacctt ctgccagcag
    77221 tggattaaga atatgccctg aatcatgaac gttgaggatg cggttgatgg tgactttgca
    77281 cagcgcaata tcgaccgtca gatcaacaaa ggtacagcca aacgccggtg ggttagtggt
    77341 ggttttgatg gagctttcag cagagagctg cccgccgcgt tcagggtggt agaaagcgtc
    77401 catcgccaaa tcttttaacg acattaacgg ctcttccggt cgttcaacca gcacgatatg
    77461 gccttttatc agggtcagat tcatcgctga ctgatgtagc atgactgcgg cgtgagcgat
    77521 gattttctct tttaataata gtgccgcact gcgcagcgca ggcgcggcaa catagctctg
    77581 gcgcgaggca aatgcgccgg gatcgaacgg cgtaacgtcg gtatcttgag ttgaaataac
    77641 gcgaacgtcg ctgaccggaa cccccacggt ttctgccacc atttgcgaga agacggtgtc
    77701 ggcaccctga ccgatttccg tcgcgccgct ttgcacgttg atggttccat cctgattcat
    77761 cagaaggcgc gcgcctgcta tttctacgcc gacaggccag gtgttagagg tgtagctaaa
    77821 acaggcgacg ccaacgccgc ggcgcaaatt gccttgctgg ttctggcatt ctgcacggcg
    77881 tttttcccat tcaaagattt tccggccttt ttcaagacac tccggcaacc ctgcgctgta
    77941 aatacgtttg cccgtgagcg gattagcatc tccttcgcgg gcggcgttgc gtaaacgaat
    78001 ttcaacagga tcaataccta acgctgtcgc ggcgtcatca agcatagact caacggcaaa
    78061 tacgacttgt ggcgcgccat aaccacgcat cgcaccagcc gaggggaggt tggtatagca
    78121 ggtctttgaa ctgtaagcgt aggcacaacg aggataaagg taagcgactt tattcccccc
    78181 cgcagaagcg atggagtgcc cgtgagatgc ataagcgccg gtgttagaca gaacatccag
    78241 actataacct ttcaatgttc cgtcgcggtt cacgcccatt tgcccgtcaa tggtaaaagc
    78301 gtggcgggta cgggttgcga ggaaacactc ttcacggcta agggaaactt tcaccggaat
    78361 gccgccaagc ttgctggtca ggaatgccgc cattggctct tccagtacat cctgtttatt
    78421 accaaaaccg ccaccgacaa atggtttgat gactcgtacg catgaccagg gaatatccag
    78481 cgcctgacca accacgcggc gaacaatgtg cgggatctgg gtgctggaaa cgatggtaat
    78541 tcgcgagtca tcctccatcc acgccagcga tgttacgctt tccatgtgac aatgttgaat
    78601 aacgggggtc tgatagtgcc cctgtacctg gtagtcggcg gcatcgattg tttgttggac
    78661 attacccgtc gacatcgtgc tttgtttcag taaattgcca ccgttatgga ttggtgcagc
    78721 gtcttctgcc agcgccgctt ctggcgtggt gataacgggt aattcttgcc actcaatgct
    78781 gaccaattgc gccgcttttt ctgccgtgag ttcatcgcgg gccacgacga tggcaacggc
    78841 gtcaccatga tgacgaacat ggcgagttag cagtgcgcga tcggcggtat cgcgcttgtt
    78901 ttcgtcaagt gtccaggcat gcccagctgt agcgaatgga atatcaggca catcttccca
    78961 ggtaaaaatc gccagtacgc ccggcaaact tctggcttgt tcatcattaa tacttacggc
    79021 ataaccatgt gcgatagggc tacgtacata tttcgcataa cacatgcccg ccataacata
    79081 atcgtcagta tatcgtgccc gcccggtgac cttagcaatg gcatcgacgc gcatgcatga
    79141 ttcacccgta gcggttgctt cccgcgcttc catagaaatc ccctcgattt gaacatttgg
    79201 ttcttatggc aaagatttag tctaagcagg caagatttac gccagaaacg acgataagcg
    79261 ttaggggagg taggaagtgt gatgacgtta aaaaaacaca gatatgatac gaaacaggac
    79321 tctgaatagg ggcagtgata cgtatcaata tgagtggcga taaaatcaat gtgataaatt
    79381 gggattatta cgcatcagga tgggaaatag ggtaaaaagt caggaagttc gatacctcta
    79441 cagcgaatat tttgctgatg atacttccct ttgccaaatg aaattaacct ctttctctat
    79501 taccacgttt ttccagaagc aagagattgg gtatcaagag gctggctgct atgataaggc
    79561 gtcttgtttt ttaagcgagg aaagattttg agtgcgggac gcctgaataa aaaatctctg
    79621 ggtatcgtga tgttgttatc ggttggactg cttttggcgg gctgttcggg tagcaaatca
    79681 tccgatacag gaacgtattc cggctccgtt tacaccgtga aacgggggga tacgctatat
    79741 cgtatttcgc gcaccacggg aaccagcgta aaagaactgg cgcgactgaa cggcatttcc
    79801 cccccttaca ccattgaagt tggtcagaaa ctaaaactgg gtggggcgaa aagtagcagt
    79861 attacacgta aatcaaccgc caaatcaacg accaaaaccg catcggttac accgtcatca
    79921 gcggtaccga aatcatcctg gccgccagta gggcaacgtt gttggttatg gccaacgaca
    79981 gggaaagtta tcatgccgta ttcgacagca gatggcggca ataaagggat tgatatctca
    80041 gctccacggg gtacacctat ttacgccgcg ggtgcaggaa aggtggtgta tgtgggcaac
    80101 cagctgcgtg gctacggtaa tctcatcatg attaaacaca gtgaagatta cattacggct
    80161 tacgcccata atgacacgat gctggtaaat aatgggcaaa gcgtgaaggc tgggcaaaaa
    80221 atcgccacta tggggagcac ggatgcggca tctgttcgcc tgcatttcca gattcgttac
    80281 cgtgcaacgg caattgatcc gctacgttac ttgccgcctc agggcagcaa gccaaaatgc
    80341 tgatggcgaa ttaatcagca gtcagcagcg tggcacttgc taaggagagc gtaaggttta
    80401 taatgcctta cgcatctcga agcgggcgta gttcaatggt agaacgagag cttcccaagc
    80461 tctatacgag ggttcgattc ccttcgcccg ctccaattta tcttcgccgt aatacttccc
    80521 cattttgttg taaataaaaa gcgtttacgc aatgcaatcc ttttgtaaca acccaggtaa
    80581 aacaccttat tttcaagttg ttaaataagt ggttatctac gcttttaaca aacgattgat
    80641 ggaatatttt atgaaaggga aatctgcatt aactcttctg ctcgctggta tattttcgtg
    80701 cggcacatgc caggcgacag gggcagaagt gacgagtgaa tctgtattta acattcttaa
    80761 ttccacgggg gcagcaacag ataaaagtta tttatcgtta aatccagata agtatcctaa
    80821 ttatcgtctt ctgattcact cagccaaatt acaaaatgaa ataaagagcc actataccaa
    80881 agacgaaatt caaggattgc taacattaac agaaaacaca cgaaagttaa cgttgacgga
    80941 gaaaccctgg ggaacgttta ttcttgcttc tactttcgaa gatgacaaaa cagcggcaga
    81001 aacccactat gatgctgtct ggttgaggga tagtttatgg ggctatatgg cattagtatc
    81061 agatcaggga aatagtgtag ccgcaaaaa
//
LOCUS       DAPHKZ010000005        79748 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.005, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000005 DAPHKZ010000000
VERSION     DAPHKZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 79748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79748
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.005"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            141..401
                     /gene="iraP"
                     /locus_tag="RH288_000304"
     CDS             141..401
                     /gene="iraP"
                     /locus_tag="RH288_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HDV4029406.1"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ"
     gene            502..1917
                     /gene="phoA"
                     /locus_tag="RH288_000305"
     CDS             502..1917
                     /gene="phoA"
                     /locus_tag="RH288_000305"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HDV4029407.1"
                     /translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGRGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNAVTEANQQKP
                     LLGLFADGNMPVRWQGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     gene            2036..2356
                     /gene="psiF"
                     /locus_tag="RH288_000306"
     CDS             2036..2356
                     /gene="psiF"
                     /locus_tag="RH288_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414918.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HDV4029408.1"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     gene            2458..3573
                     /gene="adrA"
                     /locus_tag="RH288_000307"
                     /gene_synonym="dgcC"
     CDS             2458..3573
                     /gene="adrA"
                     /locus_tag="RH288_000307"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HDV4029409.1"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     gene            complement(3590..4399)
                     /gene="proC"
                     /locus_tag="RH288_000308"
     CDS             complement(3590..4399)
                     /gene="proC"
                     /locus_tag="RH288_000308"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDV4029410.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     gene            4519..4983
                     /locus_tag="RH288_000309"
     CDS             4519..4983
                     /locus_tag="RH288_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDV4029411.1"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAAINPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRGQM"
     gene            5160..5684
                     /gene="aroL"
                     /locus_tag="RH288_000310"
     CDS             5160..5684
                     /gene="aroL"
                     /locus_tag="RH288_000310"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HDV4029412.1"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
     gene            5734..5925
                     /gene="yaiA"
                     /locus_tag="RH288_000311"
     CDS             5734..5925
                     /gene="yaiA"
                     /locus_tag="RH288_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HDV4029413.1"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     gene            6183..6860
                     /locus_tag="RH288_000312"
     CDS             6183..6860
                     /locus_tag="RH288_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HDV4029414.1"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDNHLAHVSRRKVERDLQGVVEVLDNQGYDVIILMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFNQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLV"
     gene            6932..7216
                     /gene="ppnP"
                     /locus_tag="RH288_000313"
     CDS             6932..7216
                     /gene="ppnP"
                     /locus_tag="RH288_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDV4029415.1"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            7364..7705
                     /locus_tag="RH288_000314"
                     /pseudo
     CDS             7364..7705
                     /locus_tag="RH288_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308469.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing protein"
     gene            7702..7785
                     /locus_tag="RH288_000315"
     CDS             7702..7785
                     /locus_tag="RH288_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029416.1"
                     /translation="MTQRPWSKLQRKTHNIAALKIIARRSE"
     gene            complement(7863..8774)
                     /gene="rdgC"
                     /locus_tag="RH288_000316"
     CDS             complement(7863..8774)
                     /gene="rdgC"
                     /locus_tag="RH288_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HDV4029417.1"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     gene            8899..9807
                     /gene="mak"
                     /locus_tag="RH288_000317"
     CDS             8899..9807
                     /gene="mak"
                     /locus_tag="RH288_000317"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414928.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HDV4029418.1"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFAMDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVGQLIKQFVFGGE
                     CETPVRKAKHGDSSGVRGAAWLWPQE"
     gene            complement(10054..11238)
                     /gene="araJ"
                     /locus_tag="RH288_000318"
     CDS             complement(10054..11238)
                     /gene="araJ"
                     /locus_tag="RH288_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HDV4029419.1"
                     /translation="MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMI
                     SYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSG
                     FPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTF
                     LLIAVFNIAVMASVYFWVPDIRDEAKGKLREQFHFLRSPAPWLIFAATMFGNAGVFAW
                     FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIV
                     LALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFN
                     LGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADSPVLAKP
                     LG"
     gene            complement(11364..14507)
                     /gene="sbcC"
                     /locus_tag="RH288_000319"
     CDS             complement(11364..14507)
                     /gene="sbcC"
                     /locus_tag="RH288_000319"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
                     /protein_id="HDV4029420.1"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQV
                     QSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKA
                     QPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNTWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVATALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQ
                     NVTLEQTQRNVALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGAALRGQLDALTKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDKHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRIQQLTPILETLPQSDDLPHSEETVALDNWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLAQHQQHRPDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDA
                     DNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
                     TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
                     KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
                     KINGLGYSKLESTFAVK"
     gene            complement(14504..15706)
                     /gene="sbcD"
                     /locus_tag="RH288_000320"
     CDS             complement(14504..15706)
                     /gene="sbcD"
                     /locus_tag="RH288_000320"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HDV4029421.1"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIHRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLH
                     TLAGEHEA"
     gene            15896..16585
                     /gene="phoB"
                     /locus_tag="RH288_000321"
     CDS             15896..16585
                     /gene="phoB"
                     /locus_tag="RH288_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HDV4029422.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     gene            16643..17938
                     /gene="phoR"
                     /locus_tag="RH288_000322"
     CDS             16643..17938
                     /gene="phoR"
                     /locus_tag="RH288_000322"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HDV4029423.1"
                     /translation="MLERLSWKRLVLELLLCCFPAFILGAFFGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTQLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWLRVPHGAEFSVEDNGPGIALEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD"
     gene            18345..19664
                     /gene="brnQ"
                     /locus_tag="RH288_000323"
     CDS             18345..19664
                     /gene="brnQ"
                     /locus_tag="RH288_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HDV4029424.1"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     gene            19740..21113
                     /gene="proY"
                     /locus_tag="RH288_000324"
     CDS             19740..21113
                     /gene="proY"
                     /locus_tag="RH288_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HDV4029425.1"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     gene            21269..23086
                     /gene="malZ"
                     /locus_tag="RH288_000325"
     CDS             21269..23086
                     /gene="malZ"
                     /locus_tag="RH288_000325"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HDV4029426.1"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHNMQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
                     RLDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     TALFALYQRMIALRKKSQALRHGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPFLNAVQWQCKEGHGQLTDGILALPAISATVWMN"
     gene            complement(23091..23672)
                     /gene="acpH"
                     /locus_tag="RH288_000326"
     CDS             complement(23091..23672)
                     /gene="acpH"
                     /locus_tag="RH288_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HDV4029427.1"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFV
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
                     DSWYDLDAHYDALETRFWQFYPRMMAQASRKAL"
     gene            23765..24835
                     /gene="queA"
                     /locus_tag="RH288_000327"
     CDS             23765..24835
                     /gene="queA"
                     /locus_tag="RH288_000327"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDV4029428.1"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     gene            24891..26018
                     /gene="tgt"
                     /locus_tag="RH288_000328"
     CDS             24891..26018
                     /gene="tgt"
                     /locus_tag="RH288_000328"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDV4029429.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     gene            26041..26373
                     /gene="yajC"
                     /locus_tag="RH288_000329"
     CDS             26041..26373
                     /gene="yajC"
                     /locus_tag="RH288_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDV4029430.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            26401..28248
                     /gene="secD"
                     /locus_tag="RH288_000330"
     CDS             26401..28248
                     /gene="secD"
                     /locus_tag="RH288_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HDV4029431.1"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     gene            28259..29230
                     /gene="secF"
                     /locus_tag="RH288_000331"
     CDS             28259..29230
                     /gene="secF"
                     /locus_tag="RH288_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HDV4029432.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            29359..29706
                     /locus_tag="RH288_000332"
     CDS             29359..29706
                     /locus_tag="RH288_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HDV4029433.1"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     gene            complement(29883..30767)
                     /gene="tsx"
                     /locus_tag="RH288_000333"
     CDS             complement(29883..30767)
                     /gene="tsx"
                     /locus_tag="RH288_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HDV4029434.1"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     gene            complement(31066..31605)
                     /locus_tag="RH288_000334"
     CDS             complement(31066..31605)
                     /locus_tag="RH288_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HDV4029435.1"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     QETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDADGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     ISVDQLGFVRIHDIQPVMQ"
     gene            31756..32205
                     /gene="nrdR"
                     /locus_tag="RH288_000335"
     CDS             31756..32205
                     /gene="nrdR"
                     /locus_tag="RH288_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HDV4029436.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     gene            32209..33312
                     /gene="ribD"
                     /locus_tag="RH288_000336"
     CDS             32209..33312
                     /gene="ribD"
                     /locus_tag="RH288_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDV4029437.1"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVASMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQLLRAQSHAILTSSATVLADDPALTVRWSELDEQTQAL
                     YPQQNLRQPIRIVIDSQNRVTPVHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGSDARGLC
                     TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            33401..33871
                     /gene="ribE"
                     /locus_tag="RH288_000337"
     CDS             33401..33871
                     /gene="ribE"
                     /locus_tag="RH288_000337"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDV4029438.1"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            33891..34310
                     /gene="nusB"
                     /locus_tag="RH288_000338"
     CDS             33891..34310
                     /gene="nusB"
                     /locus_tag="RH288_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDV4029439.1"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            34388..35365
                     /gene="thiL"
                     /locus_tag="RH288_000339"
     CDS             34388..35365
                     /gene="thiL"
                     /locus_tag="RH288_000339"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HDV4029440.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     gene            35343..35861
                     /gene="pgpA"
                     /locus_tag="RH288_000340"
     CDS             35343..35861
                     /gene="pgpA"
                     /locus_tag="RH288_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDV4029441.1"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGILS"
     gene            complement(35915..36889)
                     /gene="yajO"
                     /locus_tag="RH288_000341"
     CDS             complement(35915..36889)
                     /gene="yajO"
                     /locus_tag="RH288_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="HDV4029442.1"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGKNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     gene            complement(37069..38931)
                     /gene="dxs"
                     /locus_tag="RH288_000342"
     CDS             complement(37069..38931)
                     /gene="dxs"
                     /locus_tag="RH288_000342"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDV4029443.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     gene            complement(38956..39855)
                     /gene="ispA"
                     /locus_tag="RH288_000343"
     CDS             complement(38956..39855)
                     /gene="ispA"
                     /locus_tag="RH288_000343"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HDV4029444.1"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LAEQSLDTSALEALADYIIQRNK"
     gene            complement(39855..40097)
                     /gene="xseB"
                     /locus_tag="RH288_000344"
     CDS             complement(39855..40097)
                     /gene="xseB"
                     /locus_tag="RH288_000344"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDV4029445.1"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            40303..41751
                     /gene="thiI"
                     /locus_tag="RH288_000345"
     CDS             40303..41751
                     /gene="thiI"
                     /locus_tag="RH288_000345"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDV4029446.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNK
                     TWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     gene            complement(41805..42395)
                     /gene="yajL"
                     /locus_tag="RH288_000346"
     CDS             complement(41805..42395)
                     /gene="yajL"
                     /locus_tag="RH288_000346"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414958.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HDV4029447.1"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWLDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(42358..43269)
                     /gene="panE"
                     /locus_tag="RH288_000347"
     CDS             complement(42358..43269)
                     /gene="panE"
                     /locus_tag="RH288_000347"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDV4029448.1"
                     /translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     gene            43437..43928
                     /gene="yajQ"
                     /locus_tag="RH288_000348"
     CDS             43437..43928
                     /gene="yajQ"
                     /locus_tag="RH288_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein YajQ"
                     /protein_id="HDV4029449.1"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     gene            complement(44056..45420)
                     /locus_tag="RH288_000349"
     CDS             complement(44056..45420)
                     /locus_tag="RH288_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414961.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4029450.1"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWINGMFDGQGVFLAGAMLAAVWLTVASTMKEPP
                     YVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEIEQA
                     IRQA"
     gene            complement(45569..46459)
                     /gene="cyoE"
                     /locus_tag="RH288_000350"
     CDS             complement(45569..46459)
                     /gene="cyoE"
                     /locus_tag="RH288_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HDV4029451.1"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     gene            complement(46471..46800)
                     /locus_tag="RH288_000351"
     CDS             complement(46471..46800)
                     /locus_tag="RH288_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HDV4029452.1"
                     /translation="MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            complement(46800..47414)
                     /locus_tag="RH288_000352"
     CDS             complement(46800..47414)
                     /locus_tag="RH288_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HDV4029453.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            complement(47404..49395)
                     /gene="cyoB"
                     /locus_tag="RH288_000353"
     CDS             complement(47404..49395)
                     /gene="cyoB"
                     /locus_tag="RH288_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HDV4029454.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            complement(49417..50364)
                     /gene="cyoA"
                     /locus_tag="RH288_000354"
     CDS             complement(49417..50364)
                     /gene="cyoA"
                     /locus_tag="RH288_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HDV4029455.1"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAAFDQWVAKAKQSPNTMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     gene            complement(50824..52299)
                     /gene="ampG"
                     /locus_tag="RH288_000355"
     CDS             complement(50824..52299)
                     /gene="ampG"
                     /locus_tag="RH288_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HDV4029456.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNDNFISRTAYPAGYAFAMWTLAAGVSLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     gene            complement(52343..52921)
                     /locus_tag="RH288_000356"
     CDS             complement(52343..52921)
                     /locus_tag="RH288_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414968.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV4029457.1"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     gene            53226..53543
                     /gene="bolA"
                     /locus_tag="RH288_000357"
     CDS             53226..53543
                     /gene="bolA"
                     /locus_tag="RH288_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414969.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HDV4029458.1"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     gene            53887..55185
                     /gene="tig"
                     /locus_tag="RH288_000358"
     CDS             53887..55185
                     /gene="tig"
                     /locus_tag="RH288_000358"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDV4029459.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     gene            55431..56054
                     /gene="clpP"
                     /locus_tag="RH288_000359"
     CDS             55431..56054
                     /gene="clpP"
                     /locus_tag="RH288_000359"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDV4029460.1"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            56180..57454
                     /gene="clpX"
                     /locus_tag="RH288_000360"
     CDS             56180..57454
                     /gene="clpX"
                     /locus_tag="RH288_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HDV4029461.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     gene            57642..59996
                     /gene="lon"
                     /locus_tag="RH288_000361"
     CDS             57642..59996
                     /gene="lon"
                     /locus_tag="RH288_000361"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDV4029462.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            60205..60477
                     /gene="hupB"
                     /locus_tag="RH288_000362"
     CDS             60205..60477
                     /gene="hupB"
                     /locus_tag="RH288_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HDV4029463.1"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            60669..62540
                     /gene="ppiD"
                     /locus_tag="RH288_000363"
     CDS             60669..62540
                     /gene="ppiD"
                     /locus_tag="RH288_000363"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDV4029464.1"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            62691..63062
                     /locus_tag="RH288_000364"
     CDS             62691..63062
                     /locus_tag="RH288_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDV4029465.1"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAASVAKPTAVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNLAVLTL"
     gene            63156..63554
                     /gene="fadM"
                     /locus_tag="RH288_000365"
     CDS             63156..63554
                     /gene="fadM"
                     /locus_tag="RH288_000365"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HDV4029466.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLDNSDSFQWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     gene            complement(63606..64301)
                     /gene="queC"
                     /locus_tag="RH288_000366"
     CDS             complement(63606..64301)
                     /gene="queC"
                     /locus_tag="RH288_000366"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HDV4029467.1"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGFKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLR"
     gene            complement(64366..66066)
                     /locus_tag="RH288_000367"
     CDS             complement(64366..66066)
                     /locus_tag="RH288_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HDV4029468.1"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LQAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQIMPDEE
                     NRFNALKAVFSQLMTDATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     gene            66166..66984
                     /gene="cof"
                     /locus_tag="RH288_000368"
     CDS             66166..66984
                     /gene="cof"
                     /locus_tag="RH288_000368"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HDV4029469.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDRE
                     MLVSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     gene            67137..67595
                     /gene="decR"
                     /locus_tag="RH288_000369"
     CDS             67137..67595
                     /gene="decR"
                     /locus_tag="RH288_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HDV4029470.1"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            67625..69397
                     /locus_tag="RH288_000370"
     CDS             67625..69397
                     /locus_tag="RH288_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HDV4029471.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFSLLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVNDGSEPVPEGRGE
                     LDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLAQQSGWYRD
                     MYRYQQLEAALDDAPENREEAVDA"
     gene            69390..71171
                     /locus_tag="RH288_000371"
     CDS             69390..71171
                     /locus_tag="RH288_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HDV4029472.1"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSAS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     PLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAALREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     gene            71352..71690
                     /gene="glnK"
                     /locus_tag="RH288_000372"
     CDS             71352..71690
                     /gene="glnK"
                     /locus_tag="RH288_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDV4029473.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     gene            71720..73006
                     /gene="amtB"
                     /locus_tag="RH288_000373"
     CDS             71720..73006
                     /gene="amtB"
                     /locus_tag="RH288_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HDV4029474.1"
                     /translation="MKIATIKTGLASLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINW
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRG
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(73055..73915)
                     /gene="tesB"
                     /locus_tag="RH288_000374"
     CDS             complement(73055..73915)
                     /gene="tesB"
                     /locus_tag="RH288_000374"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HDV4029475.1"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     gene            74133..74705
                     /locus_tag="RH288_000375"
     CDS             74133..74705
                     /locus_tag="RH288_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HDV4029476.1"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            complement(74736..75047)
                     /locus_tag="RH288_000376"
     CDS             complement(74736..75047)
                     /locus_tag="RH288_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HDV4029477.1"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQRYRWN
                     Y"
     gene            75210..75306
                     /gene="ffs"
                     /locus_tag="RH288_000377"
     ncRNA           75210..75306
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RH288_000377"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            75426..75779
                     /locus_tag="RH288_000378"
     CDS             75426..75779
                     /locus_tag="RH288_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 domain-containing protein"
                     /protein_id="HDV4029478.1"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DVPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAANQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     gene            complement(75821..77371)
                     /gene="pdeB"
                     /locus_tag="RH288_000379"
     CDS             complement(75821..77371)
                     /gene="pdeB"
                     /locus_tag="RH288_000379"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeB"
                     /protein_id="HDV4029479.1"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTY
                     SSRVAIRANKVATQGKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVAYIDNNV
                     PQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILP
                     LPEMNISIITWASTKMLQKGWHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIRSVFEDMGDWLRQHPQQHISINLESPVLTSEKIPQLLRDMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     gene            complement(77535..78005)
                     /locus_tag="RH288_000380"
     CDS             complement(77535..78005)
                     /locus_tag="RH288_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaC family protein"
                     /protein_id="HDV4029480.1"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS"
     gene            complement(78121..78672)
                     /gene="maa"
                     /locus_tag="RH288_000381"
     CDS             complement(78121..78672)
                     /gene="maa"
                     /locus_tag="RH288_000381"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HDV4029481.1"
                     /translation="MSTEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHT
                     LRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCML
                     APGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGA
                     VVTKDVPDNVVVGGNPARIIKKL"
     gene            complement(78844..79062)
                     /gene="hha"
                     /locus_tag="RH288_000382"
     CDS             complement(78844..79062)
                     /gene="hha"
                     /locus_tag="RH288_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HDV4029482.1"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            complement(79088..79462)
                     /gene="tomB"
                     /locus_tag="RH288_000383"
     CDS             complement(79088..79462)
                     /gene="tomB"
                     /locus_tag="RH288_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HDV4029483.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSEI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
BASE COUNT        19318 a        19832 c        21348 g        19250 t
ORIGIN      
        1 agagaaacgt ttcgctggta atcaaacaaa aaatattttc gcaaagtatt tcctttgtca
       61 taaaaataat acttccagac actatgaagt tgtgaaacat aatgttaact tctccatact
      121 ttggataagg aaatacagac atgaaaaatc tcattgctga gttgttattt aagcttgccc
      181 aaaaagaaga agagtcgaaa gaactgtgtg cgcaggtaga agctttggag attatcgtca
      241 ctgcaatgct tcgcaatatg gcgcaaaatg accaacagcg gttgattgat caggtagagg
      301 gggcgctgta cgaggtaaag cccgatgcca gcattcctga cgacgatacg gagctgctgc
      361 gcgattacgt aaagaagtta ttgaagcatc ctcgtcagta aaaagttaat cttttcaaca
      421 gctgtcataa agttgtcacg gccgagactt atagtcgctt tgtttttatt ttttaatgta
      481 tttgtacatg gagaaaataa agtgaaacaa agcactattg cactggcact cttaccgtta
      541 ctgtttaccc ctgtgacaaa agcccggaca ccagaaatgc ctgttctgga aaaccgggct
      601 gctcagggcg atattactgc acccggcggt gctcgccgct taacgggtga tcagaccgcc
      661 gctctgcgtg attctcttag cgataaacct gcaaaaaata ttattttgct gattggcgat
      721 gggatggggg attcggaaat tactgccgca cgtaattatg ccgaaggtgc gggcggcttt
      781 tttaaaggta tcgatgcctt accgcttacc gggcaataca ctcactatgc gctgaataaa
      841 aaaaccggca aaccggacta cgtcaccgac tcggctgcat cagcaaccgc ctggtcaacc
      901 ggtgtcaaaa cctataacgg cgcgctgggc gtcgatattc acgaaaaaga tcacccaacg
      961 attctggaaa tggcaaaagc cgcaggtctg gcgaccggta acgtttctac cgcagagttg
     1021 caggatgcca cgcccgctgc gctggtggca catgtgacct cgcgcaaatg ctacggtccg
     1081 agcgcgacca gtgaaaaatg tccgggtaac gcgctagaaa aaggcgggag aggatcgatt
     1141 accgaacagc tgcttaacgc tcgtgccgat gttacgcttg gcggcggcgc aaaaaccttt
     1201 gctgaaacgg caaccgccgg tgaatggcag ggaaaaacgc tgcgtgaaca ggcacaggcg
     1261 cgtggttatc agttggtgag cgatgctgcc tcactgaatg cggtgacgga agcgaaccag
     1321 caaaaacccc tgctaggact gtttgctgac ggcaatatgc cagtgcgctg gcaaggaccg
     1381 aaagcaacgt accacggcaa tatcgacaag cccgcagtta cctgtacgcc taatccgcaa
     1441 cgtaatgaca gcgtaccgac cctggcgcag atgactgata aagccattga attgttgagt
     1501 aaaaatgaga aaggcttttt cctgcaagtt gaaggtgcat caatcgataa acaggatcac
     1561 gctgcgaatc cttgtgggca aattggcgag acggtcgatc tcgacgaagc cgtacaacgg
     1621 gcgctggaat tcgctaaaaa ggatggcaac acgctggtca tagtcaccgc tgatcacgcc
     1681 cacgccagcc agattgttgc gccggacacc aaagcgccgg gcctcaccca ggcgctaaat
     1741 accaaagatg gcgcagtgat ggtgatgagt tacgggaact ccgaagagga ttcacaagaa
     1801 cataccggta gtcagctgcg tattgcggcg tatggcccac atgccgccaa tgtcgttgga
     1861 ctgaccgacc agaccgatct cttctacacc atgaaagccg ccctggggct gaaataaaac
     1921 cgcgcccggc ggtgaatttt cgctgtcggg tggttttttt gctgttagca accagactta
     1981 atggcagatc acgggcgcaa acgctcatgg ttaaaacatg aagagggatg gtgctatgaa
     2041 aataacatta ctggttacct tgcttttcgg actggttttt ttaaccaccg tcggcgctgc
     2101 cgagagaacc ttaaccccgc aacaacagcg tatgacctcc tgtaatcagc aggcgacggc
     2161 gcaggcgttg aaaggggatg ctcgtaagac ctacatgagt gattgcctga agaacagcaa
     2221 gtctgcgcct ggtgaaaaaa gtttgacgcc acagcagcaa aagatgcgcg aatgtaataa
     2281 tcaagcaacg caacaatctc tgaaaggtga tgatcgtaat aagtttatga gtgcctgcct
     2341 caagaaagcc gcctgatacc tgatagtgct aacgggtgag ctacgaaagt ggctcacccg
     2401 aaatttcata cttctgcctt tagccccgtc tctataattt gggaaaattg tttctgaatg
     2461 ttcccaaaaa taatgaatga tgaaaacttt ttcaaaaaag cggcggcgca tggggaggaa
     2521 cctcctttaa ctcctcaaaa cgaacatcag cggtccgggc tgcgcttcgc ccgtcgcgtc
     2581 agactacccc gtgcggttgg cctggctggc atgttcttac cgattgcttc aacgctggtt
     2641 tcgcacccgc cgccgggctg gtggtggctg gtgttggtcg gctgggcgtt cgtctggccg
     2701 catttagcct ggcagatagc gagcagggcc gtcgatccgc ttagccggga aatttacaac
     2761 ttaaaaaccg atgcagtatt agcgggaatg tgggtaggcg taatgggcgt aaacgtgctg
     2821 ccttccaccg cgatgttgat gattatgtgt ctgaatttga tgggggcagg cggcccccgt
     2881 ctgtttgtcg cgggtctggt gttgatggtg gtttcctgcc ttgtcaccct cgagctgacg
     2941 ggcattaccg tgtcgttcaa tagtgcgccg ctggaatggt ggctctccct tcccattatt
     3001 gtcatttatc ctctgctgtt tggctgggtc agctaccaga cggcaaccaa actggcggaa
     3061 cataaacgca ggttgcaggt catgagtacc cgcgacggca tgacgggcgt gtataaccga
     3121 cgtcattggg aaactatgtt acgcaatgaa tttgataact gtcggcggca taatcgcgat
     3181 gcaacgttac tgattatcga tatcgaccat ttcaagagca tcaacgatac ctggggccat
     3241 gatgtgggcg atgaagcgat agtggcgctt acccgacagt tacaaattac cctgcgcggt
     3301 agcgatgtga ttggtcggtt tggcggcgat gagtttgcag taatcatgtc cggtacgcca
     3361 gctgagagcg ctattaccgc catgttacga gtgcatgaag ggctaaatac attacgtttg
     3421 ccgaatacgc cacaggtaac tttacggatt agtgtggggg ttgcgccgct gaacccacaa
     3481 atgagtcact atcgtgagtg gttgaaatcg gcagatttgg cgctttacaa agcaaagaaa
     3541 gccggacgta accgcaccga agtggcggcc tgacgtccgg cgaaagtcat caggatttgc
     3601 tgagtttttc tgatttttcc atacacttcg tcatcgcttc gatcactgca gcacggaagc
     3661 ctttctcttc cagtacgcgt accgcttcaa tggtggtgcc tcccggtgag cagaccatat
     3721 ctttcagtgc ccccggatgt tctcccgttt ccagcaccat ttttgcggaa cccattactg
     3781 cctgagcggc aaatttatac gcctgggcgc gtggcatccc gcccagcacg gcggcgtcgg
     3841 ccatcgcttc gataaacata aatacgtagg ctggcgaaga accgctcaca ccgaccaccg
     3901 ggtggatcat cggctcagca attacttccg cttcgccaaa gcagcggaaa atattcagca
     3961 catcagcggt atcttctggg gttaccagcg cgtttggcgt taccgaggtc atcccggcat
     4021 taaccagcgc gggagtgttc ggcatggcgc ggataatttt ccggtcatgg cccagcgcgc
     4081 gggcaagctg gtcgagcgtg acacctgcag caatagaaac gaccagagag tctttattca
     4141 ggctggaggt gatttcgcta agcactttaa tcatgatgcc aggtttaacg gcagcaaaaa
     4201 tgatatcggc gatttgcgcc acttcttgcg ccgattctgc ggcgttgatg ccgaactggt
     4261 catgcagggc ggcaacttta tccggggagg gggtgtatac ccagatttgc cctggaagca
     4321 cctgaccgct ggcaatcaga ccgccgagaa tggcttttcc catattgccg cagccaataa
     4381 aaccgatttt cttttccatt gcctcactcc tgccgtgaaa ttcattgttt tgataatcgc
     4441 tggcagaagc ataaacagaa ctatgccgga aggcaaaagc gcgacacaat agaggattac
     4501 ccaacaaagg atgactttat gacaatttgg gtggatgccg acgcgtgtcc caatgtaatt
     4561 aaagagattt tgtatcgcgc ggcggaacgt atgcagatgc cgctggtact ggtagcaaac
     4621 cagagtttac gcgtgccgcc atcgcgattt attcgtacgc tgcgcgtcgc ggcaggtttc
     4681 gacgttgccg ataacgaaat tgtccggcag tgtgaagcgg gcgatttggt gatcaccgca
     4741 gatatacctt tggctgctga agccatcgag aaaggcgctg cggcgattaa tccgcgcggc
     4801 gaacgttaca cgccagcgac cattcgtgag cgcctgacga tgcgcgattt tatggatacc
     4861 ttacgtgcca gtgggatcca gaccggcgga ccagatagtc tttcacaacg tgaccgccag
     4921 gcctttgctg cggagctgga gaaatggtgg ctggaagtgc aacgtagtcg cggccaaatg
     4981 taatttatta tttacacttc attcttgaat atttattggt atagtaaggg gtgtattgag
     5041 attttcactt taagtggaat ttttccttta caatcgaaat tgtactagtt tgatggtatg
     5101 atcgctattc tcatgacacc ggctttcgcc gcattgcgac ctattgggga aaacccacga
     5161 tgacacaacc tctttttctg atcgggcctc ggggctgtgg taaaacaacg gtcggaatgg
     5221 cccttgccga ttcgcttaac cgtcggtttg tcgataccga tcagtggttg caatcacagc
     5281 tcaatatgac ggtcgcggag atcgtcgaaa gggaagagtg ggcgggattt cgcgccagag
     5341 aaacggcggc gctggaagcg gtaactgcgc catccaccgt tatcgctaca ggcggcggca
     5401 ttattctgac ggaatttaat cgtcacttca tgcaaaataa cgggatcgtg gtttatttgt
     5461 gtgcgccagt atcagtcctg gttaaccgac tgcaagctgc accggaagaa gatttacggc
     5521 caaccttaac gggaaaaccg ctgagcgaag aagttcagga agtgctggaa gaacgcgatg
     5581 cgctatatcg cgaagttgcg catattatca tcgacgcaac aaacgaaccc agccaggtga
     5641 tttctgaaat tcgcagcgcc ctggcacaga cgatcaattg ttgattttcg agcgcctata
     5701 cttaacgttc atcccgtgaa ataaggaaga acgatgccaa cgaaaccgcc ttatcctcgt
     5761 gaagcatata tagtgacgat tgaaaaagga aagccaggac agacggtaac ctggtaccaa
     5821 ctcagagccg atcatcctaa accagactcg ttgatcagtg aacatccgac ggctcaggaa
     5881 gcgatggatg cgaaaaaacg ctatgaggac cctgacaaag agtgaccgca tcagactgct
     5941 cggaagggat tctgagtgcc actacaaggg atctgcgtca catttttcat aattcatgtt
     6001 tttcaaataa ttagaatatt aaacaataac aatccattac tggaatcatt tggaattttt
     6061 acattatgcc gtgcacgtct gctgctacgc tttttgtcat ttgtagcaca agtaagtgtc
     6121 agcagtggtg cttaacactt gcccggtaat taacgacgaa ataaaagtaa ggtggaagaa
     6181 caatgagtgc gtcgttggcg attctaacca tcggcattgt acctatgcag gaagttttgc
     6241 cgctcctgac agaatacatt gacgaagata atatttccca tcatagcctg ctggggaagt
     6301 taagccgcga agaagtgatg gcggagtacg cgccagaagc aggcgaagac acaattctca
     6361 cattattaaa tgacaaccat ctggcccatg tttcgcgtcg caaagtagag cgtgacctgc
     6421 aaggtgtggt tgaagtgctc gataatcagg gctacgacgt cattatatta atgagtacgg
     6481 caaacattag tagtatgact gcgcgtaata cgatctttct tgagccgtcg cggatattgc
     6541 caccgctggt ttcctctatt gttgaagatc atcaggtagg ggttatcgta ccggttgagg
     6601 agttgctgac cgttcaggcg caaaaatggc aaattttgca gaaaccgccg gtattttcat
     6661 tgggtaaccc cattcatgat tcagaacaaa aaatcattga tgccgggaaa gaattactgg
     6721 caaaaggggc tgatgtcatc atgctggatt gtttgggatt taaccagcgt catcgcgatt
     6781 tactgcaaaa acagctcgat gttcctgtct tgctctctaa cgtattgatt gcacggctgg
     6841 ctgcggaatt actggtgtaa ttttgcgtga cagccagcgc ctctggcccc tatagtgaag
     6901 tagatgttca actaccagac agggccagtt tatgcttcaa agtaatgagt acttttccgg
     6961 caaagtgaaa tcgatcggct tttccagcag cagcactggt cgcgccagcg tgggtgttat
     7021 ggttgaaggc gaatacacct tcagcaccgc tgagccggaa gagatgacgg taatcagtgg
     7081 cgcgctgaat gtgttactgc ctgacgcgac cgactggcaa gtgtatgaag ccggttcggt
     7141 gtttaatgtt cccggtcaca gtgagtttca tctgcaagtt gccgaaccca cctcttatct
     7201 gtgccgctat ctgtaattcc tcgccttccc cttgaacggg agggcatttt tctgaaatat
     7261 cctttcttta acccataata atatttcctt tgctgcgatt ttttcaattt ccgatatatt
     7321 catgatttat caaggttgat ataaatatca gtgaagatct ccagatattg ttgcggaact
     7381 ggctacgata aaagataaat cagatgatga atggtggcgt gcattgctgc aaagtcgcaa
     7441 tgatcattta cgccaaacgg cattgcgcaa cgcacatacc ccggcgttgt tgttaacgac
     7501 attgactgag cctcaggatc ggtcgctggc tattaataat ccacagctgg ctgccgatgt
     7561 gaaaacggcg tggttaaaag aggatccatc attactctta tttgtcgaac aacccgatct
     7621 ttcgctgtta cgtgatttag tgaaaaccgg ggcaacgcgg aaaattcgca gtgaagcgcg
     7681 tcaccggctt gaggaaaaac aatgacacaa cgtccatgga gcaagttaca gcgtaaaacg
     7741 cataatattg ctgcgctaaa aattattgct cgccgtagcg aataattata tgcctggtgt
     7801 ggcttcgtac gccggataag acgcggcagg cgtcgcatcc ggcattaaag gaaaatcagc
     7861 aattaacgtt gtgcttcgcc acctaatcct tcaatcaggt tttgaattaa cgctgccagt
     7921 tcaccagtca tcaggatgaa atcggcatca aaacgctggg cgaaatcttc acggtcgata
     7981 tcttcgtttt gatcgcgcag ctcgtcgcag aacttcagac gcttgagcga accatcgtcg
     8041 cacatcacaa actgaatgcg ctgctgccag tcgagcgcca gtttagtcac cacttttccg
     8101 gcttcaatgt gattggtgat ctcttcgctg gtcagatctt gtttcttcgc gcggatcacg
     8161 ccgccatctt ccagcaacga tttcagctcg gcttcatcaa gcagctggaa gccctgtgcc
     8221 gcactaccgg agcgaaccca ttcggtcagc gtcagttcaa tcgggttttc catgctcaat
     8281 ggtacaaccg gtaacgaccc caggctttta cgcagtaatg ccagcgtatc ttccgctttt
     8341 ttggcactgg cgcagtccac cataatcaaa ccgttaaccg tgtcgatcca catcattgtc
     8401 tggctaaaac ggctgaaagc acgcggcagc agagagtgca gcacttcgtc tttcagcgaa
     8461 tctttttcgg ttttcttcag cttacgcgcc tgttccgctt ccagtttggc gattttcgct
     8521 tccagcgcct gtttaatcac cggagacggg aggatttttt cttctttgcg cgcgcagata
     8581 acaatttgac cattggcaac gtgcgttaac gcatcgctgt gcgatcccat cggaggaacc
     8641 cagcccatct tcgccatgtc ctggctgccg catggggtaa atgccatcga ggctagctgt
     8701 ttttccatct cttctgcacg cagcgaaatc tcgcggctaa gacggtaaac cattaaattt
     8761 ttgaaccaca gcatgataat ttccacggcc ttgtcgttaa atttagcggg catgataacg
     8821 aattgtcggc ggccttgcat tgccaatccg gttgtccgtc tctacgctat tgatattgaa
     8881 aaaaataagg agagtaccgt gcgtataggt atcgatttag gcggcaccaa aactgaagtg
     8941 attgcactgg gcgatgcagg ggagcagttg taccgccatc gtctgcccac gccgcgtgat
     9001 gattaccggc agactattga aacgatcgcc acgttggttg atatggcgga gcaggcgacg
     9061 gggcagcgcg gaacggtagg tatgggcatt cctggctcaa tttcgcctta caccggtgtg
     9121 gtgaagaatg ccaattcaac ctggctcaac ggtcagccat tcgataaaga cttaagcgcg
     9181 aggttgcagc gggaagtgcg gctggcaaat gacgctaact gtctggcggt ttcagaagca
     9241 gtagatggcg cggcagcggg agcgcagacg gtatttgccg tgattatcgg cacgggatgc
     9301 ggcgcgggcg tggcattcaa tgggcgggcg catatcggcg gcaatggcac ggcaggtgag
     9361 tggggacaca atccgctacc gtggatggac gaagacgaac tgcgttatcg cgaggaagtc
     9421 ccttgttatt gcggtaaaca aggttgtatt gaaaccttta tttcgggcac gggattcgcg
     9481 atggattatc gtcgtttgag cggacatgcg ctgaaaggca gtgaaattat ccgcctggtt
     9541 gaagaaagcg atccggtagc ggaactggca ttgcgtcgct acgagctgcg gctggcaaaa
     9601 tcgctggcac atgtcgtgaa tattctcgat ccggatgtga ttgtcctggg gggcgggatg
     9661 agcaatgtag accgtttata tcaaacggtt gggcagttga ttaaacaatt tgtcttcggc
     9721 ggcgaatgtg aaacgccggt gcgtaaggcg aagcacggtg attccagcgg cgtacgcggc
     9781 gctgcgtggt tatggccaca agagtaaaaa acgtaggcaa ttggcgcatc atgcctgatg
     9841 cgacgcttgc cgcgtcttat caggcctgca aaatgtgcca gaaccgcgta gggcggataa
     9901 ggcgttcacg ccgcatccgg caataagtgc tccgatgcct gatgcgacgc ttgtcgcgtc
     9961 ttatcaggcc tacaaaatgt gccagaaccg cgtagggcgg ataaggcgtt cacgccgcat
    10021 ccggcaataa gcaacgcgca ccgtgacagt aatctacccc agtggtttcg ccagcaccgg
    10081 actatccgcc gcttgctggc gcttatagcg accatacagc agcaacgatg acatcgcagc
    10141 aaacgaaagc agggcggcag gcagcgccac gtaattatat gccagcccca gcgtcagcat
    10201 catacctccg caatatgcgc cgacggcgct accgaggtta aacgctattt gcccacctgc
    10261 ggcacctaat aactctccgc ctttggcatt ttgcagtaac aatatttgca gaggtgctga
    10321 aagggcaaat aatcccgcgc aacaaataaa agcaaaaata agcgacgttg ttttcatgcc
    10381 gccgcagaaa aagagcatca gcagtgccag tacaatgata aagtcagtca ctgctgcaat
    10441 gcgcagtggt gaataacgtc ctgaaatcct gccacttagc atatttccca gcaccatccc
    10501 tagcccaact aacatcataa taaaggtcat cgccgtttcc gaaaaaccgg aaataaacat
    10561 catgtatggc tttacgtagc tgaaccaggc aaacacacct gcgttgccaa acatcgtggc
    10621 ggcgaaaatt aaccacgggg ccgggctgcg caaaaagtga aattgttcgc gcagctttcc
    10681 tttcgcctcg tcgcgaatat ctggcaccca aaaatagacc gatgccatca ccgcaatatt
    10741 aaaaacagcg atcaataaaa aggtgtaacg ccagctaaat tcctgactta aatacgttcc
    10801 cagcggaatg cccagcaaat tggcgactgt catcccggaa accatccccg ccacggcggc
    10861 ggtgactttt ccgggtttga taatttttga taacacgatc gctccgacgc caaaaaatgc
    10921 gccatgcgga aagccggata ccagccgacc aatggcgagc atcaggtaag acgaagagag
    10981 cgtgaacatg gcgttgccaa tgacgcacaa cgccaccaga aacaacaaga tatgtttgag
    11041 tgagtagcgg ctggaaaaga gtgcgatgat tggcgcaccg accaccaccc ccagtgcata
    11101 atacgagatc atatgcccgg cggcaggaat cgaaattcct acgttatgcg ccagctccgt
    11161 gagcacgccc ataatgccaa attcggccat ccccaaacca aacgtgccca gagccaaaga
    11221 taaaatgact tttttcatac caccatcaca accaccagaa cggctaccaa tcaccgtagc
    11281 caataaagtg atagcttgca ggataacgac cagcaaggcc aagagataat tcgcccctct
    11341 gtattcatta tcctgctgaa tagttatttc actgcaaacg tactttccag tttgctgtag
    11401 cccaggccgt tgatcttttt cactttgatc tgcaccggaa tacgctcttt catcgcttct
    11461 acgtggctaa tcacaccgat ggttttgcca ctggcgttca gggcatccag cgcatcaagg
    11521 gcggtatcca gcgtttcgct atccagcgtg ccaaaacctt catcaaggaa cagcgagtca
    11581 atacgtgttt tatggctgac cagatccgaa agcgccagcg ccagcgccag actaacgagg
    11641 aaactttcgc cgccggaaag ggtacgggta tcgcgtaccg catctgcctg ccaggtatca
    11701 acaacctcga cttccagcgc ctcgctggct ttgcgctgta acagatagcg cccgtgcagc
    11761 cgggtaagtt gctgattagc gagatggact aaattatcca gcgtcagccc ctgggcaaac
    11821 ttgcggaatt tatcgccctc tttggaacct attagcgaat tcagatatcc ccagtcctca
    11881 acctgctgcg tcatttgagc aatttgctgc attaaggttt gttgttgctg acggttatct
    11941 gcatcctgct tcagctgctg gcgaatctcg ccttgactcg tggtgttttc acgcaacttt
    12001 tggtgagttt gcgctaactc ttgctgaatc tgctccaccg tcacagtgag agccaacccg
    12061 tcaggtcggt gttgttgatg ctgtgccagc gtttctgctg tctgagtgac cagcgtttgc
    12121 gcctgacggc gctggttttc cagattctgc ttgagctgtt ccagctgcgt tagtgtttgt
    12181 tcatccatta gcgccgcaag gaacgcctgc tgatcgtcaa agacgctggc ctgtagcgcg
    12241 gtgtcaaact gcgcctgggc tttttgcaga ctttgcgccg ccagaacatc ctgttgctgt
    12301 aatgtctgct gctggctgtg taatgcgaga cattgttcat gaacctgccg ccagttatcc
    12361 agcgccacag tttcttcgct gtgcgggaga tcatcacttt gcggcaacgt ttccagaatc
    12421 ggcgtcagct gctgaatacg gttttgcagc gcggttaatt cgttctggcg ttgctgccag
    12481 ctctgcgctt cttgctgacg tgtcgccaac cagctctctt cttcatcttc ctgtggcaat
    12541 gtcagtgcat atcccgccaa tgccgttaag agctgctgct ggcgttgttc aatttgctgt
    12601 tgatactgga taatttgctg attatgcgcg gcaatctgcc cttgtaattc atgtcgttgg
    12661 ctgagtaacc gcagctggcg ttcgtgctta tcttgtgcat ccagccacgg ttgaatatcg
    12721 tcctgtggct gcaaggtgat attgaggctg gccgtgacgg cttgccattg ttgagtaagt
    12781 gcttgctcat cttgtcggag gctttgcgct tcgttttcat cgcgctgaag ctgcttcgtt
    12841 aatgcatcca gttgcccgcg cagcgccgca ccttcttcgc cgagcttttt aacttcgttt
    12901 tccagcgcca gtaatcgaga ctgattaacg ccaggctcca gcgcctgata cgcctcgacc
    12961 gccggatggc tggtggaacc acaaagtgga caaggctgac ccgcctgtaa ctgtgcacgc
    13021 tgggcttcca gcgttttgat gcgcgcttcc tgctcgcaaa tggttttcac atcggcaagt
    13081 tgctgcgtct tttctttata acgctggcgc atttcgttaa gtgcgacatt acgttgcgtc
    13141 tgttccagag tgacattctg gatagcgacc tgtaactgcg ccagacgttt ttgttgggga
    13201 acaatctgcc catgcagcgc gaccaggcgc tgacgcagtg ggcgttgctc agcatgttgc
    13261 gccagggcgg tagcaacttc atcggcggtt aacgtcaacg tgatcgccgc aagcgcatta
    13321 agtttttgct cagcatgggt taactgttgc tgccattgcc gcagatgctc gcgatcgctg
    13381 gtttgttggg agaactgcgc acgccaaccc gccagttcgt tgttccactg acggaagcgg
    13441 tcgtgttcct gtaaccaggt attcaggctt tgttgctgct gctgtaattc tgctgactgc
    13501 ttcgccgcgt ggtggcgaat gctcgcgcga agcgccattg tgctctgtaa gcgagtattt
    13561 acttcttcaa tctgctggcg aatatgcgcc agcgccgcgc tgtgttctgc gatgcgttcc
    13621 cagtgtggac gaagatttcg tgccggttgt gccagactaa gcgccgccag ttgaggttgc
    13681 gctttttctt cttcggctaa cgcctgttgc aaggcctgct gacggcggct ggcttcttgc
    13741 tgcaattcgt cctgacgcgt taaccagttt agcgattgtt gttcttgctg ctgcgcggta
    13801 attaactgtt tttcttcgtc agtaagtacc tgcaaactcg ctgtcagcga ttgcacttgt
    13861 tccggcgtga gcaacgtgac gccgctggcc tgcgcttgca gcttctccag ctctgtgcgg
    13921 gccgatttgt gctgctcaaa aaccatcgcc gagatttgcc cgtagatttc agtgccggtt
    13981 aactcctcga gcaattccgc gcgttctttg ggtttggcat tcaggaaggc agcaaattgc
    14041 ccctgcgaaa gcagcatcga acgggtgaag cgcccgtaat ccagcccggt taacgtcgct
    14101 gtcagttcca gcttatcttt cactttgtcg gcgagaattt tgccgtcggc gcagcgcgcc
    14161 agctctacgc gtggcacctg caaattaccg tcgggttggt tacgcgcccg attctggctc
    14221 cagaatgcac ggtacgcttc acctttcact tcaaactcca cctccgccag acattcggcg
    14281 gtatcgcggg tcatgagatc attttgcgat tgtgaaacgt tagagagacg cggagtttcg
    14341 tgatacagcg ccagacaaat ggcgtccagc agggtggttt tccccgcacc tgttgggccg
    14401 gtaatagcaa acagcccgtt gctggcgaac ggctcgcggg tgaaatcaat cttccattcg
    14461 ccttttaatg agttcaggtt tttcaggcgc aggctgagaa ttttcatgct tcgtgttctc
    14521 cggcgagggt atgcaacgtc gtggtgaaaa gatgctgcag acgttgctgc tgcgattcat
    14581 ccagttcttc cagtgccaga cggcgattga acacctcttc gacgctgagt tcgctgaggg
    14641 tttcacgctg ttggctggct aacacacgct cgcgctgttc acgactccga cgtaccagca
    14701 atacttcgac aggcaatgat tcggttaatg cctggatttt gcgatgaata tcatgcagat
    14761 actcatcagt agtgatttcg atatccagcc agacaggtgg ctcctgcgat acatcgcgcc
    14821 actgttccag ctgtgcggta atcgacgcca gatcgccttt cagcactgcc atgggttgcg
    14881 ttaccggtac gttcaggttt tccacgctct ctaatttgcc gtttgaaaat gtcaccagat
    14941 ggacatattt actcttaccg cattcatcaa aactcagcgg aatgggggag ccgcaatagc
    15001 gaacatgttc catgccgcca ataatctgtg cgcggtgaat atgcccgagc gcgatgtagt
    15061 cggctggtgg aaagttttgt gccggaaacg cgtccagcgt gccaatataa atgtcacgca
    15121 cggcgtcact tttactggcc cccacggtcg ttaaatgtcc cgtggcgatg atgggcagag
    15181 gctgatcgcc gcgcagtttg caggcatcgg catagtgttg ttggtaataa tcggtaatcg
    15241 ctgccagtaa atgctgctgt ttttcaatac cgttaagccc cgcctggctg gtaataatgt
    15301 cacgcggacg taaaaacgga atggggcaca gcactgcgcc tggcgtcccg tcgcgacgag
    15361 gcaagatttg cggcgcatgt ccggcgctgg cgaccacggt agtattgagg aacgccatga
    15421 tatcgcgcga ttcattcagc gtggcgaccg agtcatggtt tcctgccagt accaccagat
    15481 gacagccagt ttgctgtaaa ttgacaacaa aacggttgta taacgtgcgg gcgtaactgg
    15541 gcggcgagcc ggtatcgaaa acatcaccgg caacaataat cgcatccacc tgatgggttt
    15601 gtgctgtctc cagcagccag tcaagaaaag cctgatgttc agcttcgcgg cttttactgt
    15661 agaagttctg gccgagatgc cagtctgagg tgtgaaggat gcgcataacg gttccctggc
    15721 gaaaaagcat gggcgcgatt atacccaaac agatgtgcca tttgcttttt tctgcgccac
    15781 ggaaatcaat aacctgaaga tatgtgcgac gagcttttca taaatctgtc ataaatctga
    15841 cgcataatga cgtcgcatta atgatcgcaa cctatttatt acaacagggc aaatcatggc
    15901 gagacgtatt ctggtcgtag aagatgaagc tccaattcgc gaaatggtct gcttcgtgct
    15961 cgaacaaaat ggctttcagc cggtcgaagc ggaagattat gacagtgctg tgaatcaact
    16021 gaatgaaccc tggccggatt taattctcct tgactggatg ttacctggcg gctccggtat
    16081 ccagttcatc aaacacctca agcgcgagtc gatgacccgg gatattccag tggtgatgtt
    16141 gaccgccaga ggggaagaag aagatcgcgt gcgcggcctt gaaaccggcg cggatgacta
    16201 tatcaccaag ccgttttcgc cgaaggagct ggtggcgcga atcaaagcgg taatgcgccg
    16261 tatttcgcca atggcggtgg aagaggtgat tgagatgcag ggattaagtc tcgacccgac
    16321 atctcaccga gtgatggcgg gcgaagagcc gctggagatg gggccgacag aatttaaact
    16381 gctgcacttt tttatgacgc atcctgagcg cgtgtacagc cgcgagcagc tgttaaacca
    16441 cgtctgggga actaacgtgt atgtggaaga tcgtacggtc gatgtccaca ttcgtcgcct
    16501 acgtaaagca ctggagccag gcgggcatga ccgcatggtg cagaccgtgc gcggtacagg
    16561 atatcgtttt tcaacccgct tttaacgcct tgctcatcgg acgcagggca gggcttatga
    16621 tttcttaact ggagtatctt acgtgctgga acggctgtcg tggaaaaggc tggtgctgga
    16681 gctgctactt tgctgcttcc cggctttcat cctgggtgca ttttttggtt acctgccctg
    16741 gtttttgctg gcatcggtaa cgggactgct tatctggcat ttctggaatt tattgcgcct
    16801 ttcatggtgg ctgtgggtgg atcgtagtat gaccccgcca ccggggcgtg gtagctggga
    16861 accgctacta tacggcttac accagatgca gctgcgaaat aaaaaacgcc gccgtgaact
    16921 gggcaatctg attaaacgct ttcgtagcgg cgcggagtcg ctgcccgacg cagtggtgct
    16981 gaccacggaa gagggcggta ttttctggtg taacggtctg gcgcaacaaa ttcttggttt
    17041 gcgctggccg gaagataacg ggcagaacat ccttaacctg ctgcgttacc cggagtttac
    17101 gcaatatctg aaaacgcgtg atttttctcg cccgctcaat ctggtgctca acaccgggcg
    17161 gcatctggaa attcgcgtca tgccttatac ccacaaacag ttgctgatgg tggcgcgtga
    17221 tgtcacgcaa atgcatcaac tggaaggggc gcggcgtaac ttttttgcca acgtgagcca
    17281 tgagttacgt acgccattga ccgtgttaca gggttacctg gagatgatgg atgagcagcc
    17341 gctggaaggc gcggtacgcg aaaaagcgtt gcacaccatg cgcgagcaga cccagcggat
    17401 ggaagggctg gtgaagcagt tgctaacgct gtcgaaaatt gaagccgcgc cgacgcaatt
    17461 gctcaatgaa aaggttgatg tgccgatgat gctgcgcgtt gttgagcgcg aggctcagac
    17521 tctgagtcag aaaaaacaga catttacctt tgagatagat aacggcctca aggtgtctgg
    17581 caacgaagat cagctacgca gtgcgatttc gaacctggtc tataacgccg tgaatcatac
    17641 gccggaaggc acgcatatca ccgtacgctg gctgcgagtg ccgcacggtg ccgaatttag
    17701 cgttgaagat aacggaccgg gcattgcact ggagcatatt ccgcgcctga ccgagcgttt
    17761 ttatcgcgtt gataaagcgc gttcccggca aaccggcggt agcggattag ggttagcgat
    17821 cgtgaaacat gcggtgaatc atcacgaaag tcgcctgaat attgagagta cagtaggaaa
    17881 aggaacacgt ttcagttttg ttatcccgga acgtttaatt gccaaaaaca gcgattaatc
    17941 cgcctttgtc atcttttatt gccataagcc agccgatgct ggcttatttt ctttgcagtc
    18001 aaaatacggg cgttagattt tacaacggtt ggtgattttt tgttcgcatg attagccatg
    18061 tctttttcac ggaaatagtg ttttatactg gttggtgatt tcttatcgct atatacctct
    18121 ggtttttaga tccctccttg ctttaaaacg ttataagcgt ttaaattgcg cttcaggtgc
    18181 tgtcatactg actgcattaa cgcggtaaat cgaaaaacta ttcttcgccg cgcctggttg
    18241 ggagtatttc ccgctaaaat tgtttaaata taccgctgta tcatccccag ggattggcac
    18301 aaaaatttaa cgttacaaca ccacatccac aggcagtatg atttatgacc catcaattaa
    18361 gatcgcgcga tatcatcgct ctgggcttta tgacatttgc gttgttcgtc ggcgcaggta
    18421 acattatttt ccctccaatg gtcggcttac aggcaggcga acacgtctgg actgcggcat
    18481 tcggcttcct cattactgcc gttggcctgc cggtattaac ggtagtggcg ctggcaaaag
    18541 ttggcggcgg tgttgacagc ctcagcacgc caatcggtaa agttgctggc gtactgctgg
    18601 caacggtttg ttacctggcg gtggggccgc ttttcgctac gccgcgtaca gctaccgttt
    18661 cctttgaagt ggggattgcg ccgctgacgg gtgattccgc gctgccgctg tttatctaca
    18721 gcctggtcta tttcgctatc gttattctgg tttcgctcta tccgggcaag ctgctggata
    18781 ccgtgggcaa cttccttgcg ccgctgaaaa ttatcgcgct ggtcatcctg tctgttgccg
    18841 cgattgtctg gccggcgggt tctatcagca cggcgactga ggcttatcaa aacgctgcgt
    18901 tttctaacgg cttcgttaac ggctatctga ccatggatac gctgggcgca atggtgtttg
    18961 gtatcgttat tgttaacgcg gcgcgttctc gtggcgttac cgaagcgcgt ctgctgaccc
    19021 gttataccgt ctgggctggc ctgatggcgg gtgttggtct gactctgctg tacctggcgc
    19081 tgttccgtct ggggtcagac agcgcgtcgc tggtcgatca gtctgcaaac ggcgctgcta
    19141 ttctgcatgc ttacgttcag cacacctttg gcggcggcgg tagcttcctg ctggcggcgt
    19201 taatcttcat cgcctgcctg gtaacggcag ttggcctgac ctgtgcttgt gcagaattct
    19261 ttgcccagta cgtaccgctc tcttatcgta cgctggtgtt tatcctcggc ggcttctcga
    19321 tggtggtttc taacctcggc ttaagccagc tgatccagat ctccgtaccg gtgctgaccg
    19381 ctatttatcc gccgtgtatc gcactggttg tattaagttt tacacgctca tggtggcata
    19441 attcgtcccg cgtgattgct ccgccgatgt ttatcagcct gctttttggt attctcgacg
    19501 ggatcaaagc atctgcattc agcgatatct taccgtcctg ggcgcagcgt ttaccgctgg
    19561 ccgaacaagg tctggcgtgg ttaatgccaa cagtggtgat ggtggttctg gccattatct
    19621 gggatcgcgc ggcaggtcgt caggtgacct ccagcgctca ctaaatcact gaacatttgt
    19681 tttaaccacg gggctgcgat gccccgtggt tttttattgt gttgatgggt taggaattga
    19741 tggaaagtaa gaacaagcta aagcgtgggc taagtacccg ccacatacgc tttatggcac
    19801 tgggttcagc aattggcacc gggctgtttt acggttcggc agacgccatc aaaatggccg
    19861 gtccgagcgt gttgttggcc tatattatcg gtggtatcgc ggcgtatatc attatgcgtg
    19921 cgctggggga aatgtcggta cataacccgg ccgccagctc tttctcgcgt tatgcgcagg
    19981 aaaacctcgg cccgctggca ggttacatta ccggctggac ctactgcttt gaaatcctta
    20041 ttgtcgccat cgccgatgtg accgcttttg gtatctatat gggtgtctgg ttcccgacgg
    20101 tgccgcactg gatttgggta ctgagcgtgg tgctgatcat ttgcgccgta aacctgatga
    20161 gcgtgaaggt attcggtgag ctggaattct ggttctcgtt ctttaaagtc gccaccatca
    20221 tcatcatgat tgtcgccggt ttcggcatca tcatctgggg gattggcaac ggcgggcaac
    20281 cgaccggtat tcataacctg tggagcaacg gcggcttctt cagtaacggc tggcttggca
    20341 tggtaatgtc gttgcaaatg gtgatgtttg cttacggtgg gatcgaaatt atcgggatta
    20401 ccgccggtga agcgaaagat cctgagaaat cgataccgcg tgcgattaac tccgtgccga
    20461 tgcgtattct ggtgttctac gtcggtacgc tgttcgtcat tatgtctatc tacccgtgga
    20521 atcaggttgg cactgccggt agcccgttcg tgctgacgtt ccagcatatg ggcattacct
    20581 ttgccgccag cattcttaac tttgttgtgc tgactgcttc gctgtcggca attaacagtg
    20641 atgtatttgg cgtaggccgt atgctccacg gtatggcaga gcagggcagc gcgccgaaaa
    20701 ttttcagcaa aacgtcgcgt cgcggtattc cgtgggttac ggtgctggtg atgactaccg
    20761 cgctgctgtt tgcggtgtat ctgaactaca tcatgccgga aaacgtcttc ctggtgatcg
    20821 cttcgctggc aaccttcgcc acggtgtggg tgtggattat gatcctgctg tcgcaaattg
    20881 ccttccgtcg ccgtttgccg ccagaagaag ttaaggcgct gaaatttaaa gtgccgggtg
    20941 gggtagcaac gaccatcggc gggctgattt tcctgctctt tattatcggg ttgattggtt
    21001 atcacccgga tacgcgtatc tcgctgtatg tcggtttcgc gtggattgtt gtgctgttga
    21061 ttggctggat gtttaaacgc cgccacgatc gtcagctggc tgaaaaccag taatccttgc
    21121 gttctgtaag ccggttcagg aggaaatcct gatccggcta ttccgaaagt tatccgcccc
    21181 cgtcctcctc ccccaaatat ccttcagatg atgagtgatc ctgcattagg ctatggcaag
    21241 gtgatcagat tttcatcaca ggggaattat gatgttaaat gcatggcacc tgccggtgcc
    21301 cccatttgtt aaacaaagca aagatcaact gctcattaca ctgtggctga cgggcgaaga
    21361 cccaccgcag cgcattatgc tgcgtacaga acacgataac gaagaaatgt cagtaccgat
    21421 gcataagcag cgcagtcagc cgcagcctgg cgtcaccgca tggcgtgcgg cgattgatct
    21481 ctccagcgga caaccccggc ggcgttacag tttcaaactg ctgtggcacg atcgccagcg
    21541 ttggtttaca ccgcagggct tcagccgaat gccgccggca cgactggagc agtttgccgt
    21601 cgatgtaccg gatatcggcc cacaatgggc tgcggatcag attttttatc agatcttccc
    21661 tgatcgtttt gcgcgtagtc ttcctcgtga agctgaacag gatcatgtct attaccatca
    21721 tgcagccgga caagagatca tcttgcgtga ctgggatgaa ccggtcacgg cgcaggcggg
    21781 cggatcaacg ttctatggcg gcgatctgga cgggataagc gaaaaactgc cgtatctgaa
    21841 aaagcttggc gtgacagcgc tgtatctcaa tccggtgttt aaagctccca gcgtacataa
    21901 atacgatacc gaggattatc gccatgtcga tccgcagttt ggcggtgatg gggcgttgct
    21961 gcgtttgcga cacaatatgc agcagctggg aatgcggctg gtgctggacg gcgtgtttaa
    22021 ccacagtggc gattcccatg cctggtttga caggcataat cgtggcacgg gtggtgcttg
    22081 tcacaacccc gaatcgccct ggcgcgactg gtactcgttt agtgatgatg gcacggcgct
    22141 cgactggctt ggctatgcca gcttgccgaa gctggattat cagtcggaaa gtctggtgaa
    22201 tgaaatttat cgcggggaag acagtattgt ccgccactgg ctgaaagcgc cgtggaatat
    22261 ggacggctgg cggctggatg tggtgcatat gctgggggag gcgggtgggg cgcgcaataa
    22321 tatgcagcac gttgccggga tcaccgaagc ggcgaaagaa acccagccgg aagcgtatat
    22381 tgtcggcgaa cattttggcg atgcacggca atggttacag gccgatgtgg aagatgccgc
    22441 catgaactat cgtggcttca cattcccgtt gtggggattt cttgccaata ccgatatctc
    22501 ttacgatccg cagcaaattg atgcccaaac ctgtatggcc tggatggata attaccgcgc
    22561 agggctttct catcaacaac aattacgtat gtttaatcag ctcgacagcc acgatactgc
    22621 gcgatttaaa acgctgctcg gtcgggatat tgcgcgcctg ccgctggcgg tggtctggct
    22681 gttcacctgg cctggtgtac cgtgcattta ttacggtgat gaagtaggac tggatggcaa
    22741 aaacgatccg ttttgccgta aaccgttccc ctggcaggtg gaaaagcagg atacggcgtt
    22801 attcgcgctg taccagcgaa tgattgcgct gcgtaagaaa agtcaggcgc tacgtcatgg
    22861 cggctgtcag gtgctgtatg cggaagataa cgtggtggta tttgtccgcg tgctgaatca
    22921 gcaacgtgta ctggtggcaa tcaaccgtgg cgaggcctgt gaagtggtgc tacccgcgtc
    22981 accgtttctc aatgccgtgc aatggcaatg caaagaaggg catgggcaac tgactgacgg
    23041 gattctggct ttgcctgcca tttcggctac ggtatggatg aactaacgtt ttataacgcc
    23101 ttgcgtgacg cctgcgccat catccgcgga taaaactgcc agaagcgggt ttcgagggcg
    23161 tcataatgag cgtctaaatc gtaccaggag tcacgcaggg catccagacg tgggcggcgg
    23221 cttgccatgc cgtttaacac gttctggatg aaatccatat cgcgatagcg caccagccac
    23281 tgctctgacc acaagtaatt gttcagattg ataaaacgtg gcggtgagtc cggcaaaatc
    23341 gtcatcactt gctcgcgggc ataacagaca aattcctgta gcggaaagtc cggcgacagc
    23401 tgcgaccagt ggcgggaaag aaagtgatcc cacatgacat ccagcgtaat aggcgcaacg
    23461 cggcgcgttt cactacgaaa ccactcccgt gcttcgcgga cttccggcag attgtcagtc
    23521 aatacgtcga tacgtcgatg catatgaatg ccagccacga cgtcgggcgg aaaactttct
    23581 tcaggatttc cgcgtacgaa atcagccagt aaattgccgg aaagcgagct ttccgcgaga
    23641 tgggctaaat gcaggtgagc taaaaaattc atcgattata ttctatccaa aagggggtaa
    23701 aggttgcagg gagagcgccc cggcactaga ctacccgcct cttattttag tctgagtcag
    23761 tgtcatgcgc gttaccgatt tctcctttga attgcccgaa tccctgattg cccactatcc
    23821 catgcctgaa cgcagtagct gtcgtttact gtcgctggac gggccgacgg gcgcgctgac
    23881 gcacggtact ttcaccgatt tacttgataa gctcaacccc ggcgatcttc tggtttttaa
    23941 taatacccgc gtgatcccgg cgcgcctgtt tgggcgtaaa gccagcggcg gcaagattga
    24001 agtgctggtt gaacggatgc tcgacgacaa acgcattctt gcgcatattc gcgcctcgaa
    24061 agcgccaaaa cctggcgcag aactgctgct gggcgatgac gaaagtatta acgcaacaat
    24121 gaccgcgcgc cacggcgcac tgtttgaagt cgaatttaat gatgaacgct cggtgctgga
    24181 tattctcaac agcatcggcc atatgccgct gccgccgtat atcgaccgtc cggacgaaga
    24241 cgctgaccgc gaactttatc aaaccgttta tagcgaaaaa ccgggcgcgg ttgcagcccc
    24301 gaccgcaggt ctgcattttg acgagccttt gctggaaaaa ttgcgcgcca aaggcgtgga
    24361 gatggcgttt gtgacgttgc acgttggtgc gggcaccttc cagccggtgc gcgtcgacac
    24421 cattgaagat cacatcatgc actcggaata cgctgaagta ccgcaggatg tggtagacgc
    24481 ggtactggcg gcgaaagcgc gcggtaaccg ggtgattgcg gttggcacca cttcagtacg
    24541 ttcgctggaa agcgcggctc aggcagcgaa aaacgatctc attgaaccgt tcttcgacga
    24601 tacccaaatc tttatctatc cgggcttcca gtacaaagtg gtcgatgcgc tggtgacgaa
    24661 cttccacttg ccagagtcga cgctgattat gctggtttcg gcctttgccg gttatcaaca
    24721 caccatgaac gcctataaag cagcggtaga agagaaatat cgctttttta gttacggtga
    24781 tgcgatgttt atcacgtaca atccgcaggc aattaatgag cgcgtcgggg agtaattccg
    24841 cggcgctggt ttaaaacgtt ggactgtttt tctgacgtag tggagaaaaa atgaaatttg
    24901 aactggacac caccgacggt cgcgcacgcc gtggccgcct ggtctttgat cgtggcgtag
    24961 tggaaacgcc ttgttttatg cctgttggca cctacggcac cgtaaaaggg atgacgccgg
    25021 aagaagttga agccactggc gcgcaaatta tcctcggcaa caccttccac ctgtggctgc
    25081 gcccgggcca ggaaatcatg aaactgcacg gcgatctgca cgattttatg cagtggaagg
    25141 ggccgatcct caccgactcc ggcggcttcc aggtcttcag ccttggcgat attcgtaaaa
    25201 tcaccgaaca gggcgtgcac ttccgtaacc cgatcaacgg cgatccgatt ttcctcgatc
    25261 ctgaaaaatc aatggagatt cagtacgatc ttggttcgga tatcgtcatg atctttgatg
    25321 agtgtacgcc gtatcctgct gactgggatt acgcaaaacg ctccatggag atgtctctgc
    25381 gttgggcgaa gcgtagccgt gagcgttttg acagtctcgg aaacaaaaat gcgctgtttg
    25441 gtatcatcca gggcagcgtt tacgaagatt tacgtgatat ttctgttaaa ggtctggtag
    25501 atatcggttt tgatggctac gctgtcggcg gtctggctgt gggtgagccg aaagcagata
    25561 tgcaccgcat tctggagcat gtatgcccgc aaattccggc agacaaaccg cgttacctga
    25621 tgggcgttgg taaaccagaa gacctggttg aaggcgtacg tcgtggtatc gatatgtttg
    25681 actgcgtaat gccaacccgc aacgcccgaa atggtcattt gttcgtgacc gatggcgtgg
    25741 tgaaaatccg caatgcgaag tataagagcg atactggccc actcgatcct gagtgtgatt
    25801 gctacacctg tcgcaattat tcacgcgctt acttgcatca tcttgaccgt tgcaacgaaa
    25861 tattaggcgc gcgactcaac accattcata accttcgtta ctaccagcgt ttgatggcgg
    25921 gtttacgcaa ggctattgaa gagggtaaat tagagagctt cgtaactgat ttttaccagc
    25981 gtcaggggcg agaagtacca cctttgaacg ttgattaata ttaataatga gggaaattta
    26041 atgagctttt ttatttctga tgcggtagcg gcaacgggtg caccggcgca aggtagcccg
    26101 atgtctttga ttttgatgct ggtggtattc ggtctgattt tctatttcat gatcctgcgt
    26161 ccacagcaga agcgcaccaa agaacacaaa aagctgatgg actccattgc caaaggtgat
    26221 gaagttctga cgaacggtgg cctggttggt cgcgtaacca aagtagcgga aaacggctac
    26281 attgctatcg cgctgaatga caccactgaa gtagttatta aacgtgactt cgtagctgcc
    26341 gtcctgccga aaggcaccat gaaggcgctg taattaaaat ttttccctaa gggaattgcc
    26401 gtgttaaacc gttatccttt gtggaagtac gtcatgctga tcgtggtgat tgtcatcggt
    26461 ctgctgtatg cgcttcccaa cctgtttggt gaggatccgg ctgttcagat cactggtgcg
    26521 cgcggagtcg ccgccagtga gcaaacgctg atccaggtcc agaaaacgtt acaagaagaa
    26581 aaaataactg ctaagtctgt ggcactggaa gagggcgcta ttcttgcgcg cttcgactcc
    26641 actgacaccc agttgcgcgc tcgtgaagca ttaatgggcg ttatgggtga caaatacgtc
    26701 gtggcgctta accttgcccc ggcaacgccg cgctggctgg cagctattca cgctgagccg
    26761 atgaagctcg gccttgacct gcgtggcggc gttcacttcc tgatggaagt ggatatggac
    26821 accgcgcttg gcaaactcca ggaacaaaat atcgatagcc tacgcagtga cctgcgcgaa
    26881 aagggcatcc cgtataccac tgttcgtaaa gaaaacaact acggcctgag catcactttc
    26941 cgcgatgcta aagctcgtga tgaagccatt gcgtatctga gcaagcgcca tccggacctg
    27001 gtgattagca gccagggcag caaccagctg cgtgcggtaa tgagcgatgc tcgtctgagt
    27061 gaagcgcgtg aatatgcggt gcagcagaac attaatatcc tgcgtaaccg tgtaaaccaa
    27121 cttggcgtgg cggagccggt ggttcagcgt cagggtgctg accgtatcgt tgttgaactg
    27181 ccaggtattc aggacactgc gcgtgcgaaa gagattctgg gtgcgacggc aacgctggaa
    27241 ttccgtctgg taaacaccaa cgttgaccag gccgctgcgg catccggtcg cgtaccgggc
    27301 gactctgaag tgaaacagac ccgcgaaggt cagccagttg tgctgtacaa acgcgtaatt
    27361 ctgaccggtg accatatcac cgactccact tccagccagg acgaatacaa ccaaccgcag
    27421 gttaacatct cgctcgatag cgctggtggt aacatcatgt ctaacttcac taaggacaac
    27481 atcggcaaac cgatggcaac cctgtttgtg gagtacaaag acagcggtaa gaaagatgca
    27541 aatggtcgtg cggttctggt gaaacaggaa gaggtgatta acatcgccaa catccagtct
    27601 cgtctgggta acagcttccg tatcaccggc atcaacaacc cgaacgaagc ccgtcagctg
    27661 tcactgctgc tgcgtgccgg tgcgttgatc gcgccgattc agattgttga agaacgtacc
    27721 attggcccaa ccctgggtat gcagaacatt gaacaggggc tggaggcttg ccttgccggt
    27781 ctgctggttt ctattctgtt catgatcatc ttctataaga agtttggtct gattgcgacc
    27841 agtgctctga ttgccaactt gatcttaatc gtcggcatta tgtcgctgtt gccaggcgca
    27901 acgctgagta tgccaggtat cgcgggtatc gtcttaaccc ttgcggtggc ggtcgatgcg
    27961 aacgtactga tcaacgaacg tattaaagaa gagttgagca acggacgtac tgttcaacag
    28021 gcaattgatg aaggttatcg tggcgcattc agttctatct tcgatgcgaa catcaccacg
    28081 ctgattaaag tcatcatcct gtacgcagtg ggtaccgggg caattaaagg gttcgcgatt
    28141 actaccggta tcggtgtggc gacgtcgatg tttaccgcga ttgtcggtac gcgtgccatc
    28201 gtaaacctgc tatatggcgg caagcgcgtc aagaagctgt caatctgagg agtgcgatgt
    28261 ggcacaggaa tatactgttg aacaactaaa ccacggccgt aaagtctatg actttatgcg
    28321 ctgggactac tgggctttcg gcatctctgg tctgctgtta atcgctgcta tcgttattat
    28381 gggcgtgcgc ggctttaact gggggctgga tttcaccggt ggtacggtta ttgaaattac
    28441 gctcgaaaaa ccggctgaaa ttgacgtaat gcgtgatgca ttgcaaaaag ccggttttga
    28501 agagccgatg ctgcaaaact ttggtagcag ccatgacatc atggtccgta tgccgcctgc
    28561 tgaaggcgaa accggcggtc aggtgttggg cagccaggtt ctgaaggtga ttaacgaatc
    28621 caccaatcag aatgcagcag tgaagcgtat tgagttcgtc ggtccgagcg tgggggcaga
    28681 ccttgcgcaa accggtgcga tggcgttgat ggcagcgctg ctgtctatcc tcgtgtacgt
    28741 aggtttccgc tttgagtggc gactggcggc aggggtggtt attgcgctgg cgcacgacgt
    28801 tatcattacg ctgggtattt tgtcgttatt ccatatcgag attgacctga ccattgtggc
    28861 atcgttgatg tcggttatcg gttactcgct taacgacagt atcgtggtat cggaccgtat
    28921 tcgtgaaaac ttccgcaaga tccgtcgcgg tacgccttac gaaatcttta acgtgtcctt
    28981 gacccagacg ctgcaccgta ccttgatcac atccggtact accttgatgg ttatcctgat
    29041 gctgtacctc ttcggtggtc cggtactgga aggcttctcg ctgaccatgc ttatcggtgt
    29101 ttccatcggt actgcatctt ccatctatgt ggcatctgcg ttggctctga aactgggtat
    29161 gaagcgcgaa cacatgttgc agcagaaagt ggaaaaagaa ggggcggatc agccgtcaat
    29221 tctgccgtaa tcaagttccc gttgatgttg aaaatcccgg tcagaagatc gggatttttt
    29281 ttgatgtatg gagattgcga aaatccccgc atcttgggaa actgcgcgta accctacatt
    29341 tcatccaggt aacttttcat ggctatcatc ccaaaaaact atgcgcggtt agaaagcggc
    29401 tatcgcgaaa aagcattaaa aatctatccg tgggtctgcg gtcgctgttc ccgcgagttt
    29461 gtttattcca acctgcgtga acttaccgtt caccacattg atcacgacca taccaataac
    29521 ccggaagatg gcagtaactg ggaattgttg tgtctctatt gccacgatca tgagcattcg
    29581 aaatataccg aagcggatca gtatggtacg accgttatcg caggggaaga tgcgcagaaa
    29641 gatgtcggtg aagcgaagta caacccattc gctgacctga aagcgatgat gaacaagaag
    29701 aagtgattaa aacgtaaaat tgcctgatgc gctacgctta tcaggcctac gttatttcag
    29761 caatatattg aatttacgtg cttttgttgg ccggacaaag cgtttacgcc gcatccggca
    29821 tgaacaaagc acacgttgtt aacaatcaga aatgccggga ataaatcccg gcattttcat
    29881 aatcagaagt tgtaacctac taccaggtaa ccaccccagc cggtagagcg aacgttgaag
    29941 ttgccgttgc cgaagttcag ttctgcatcg tcgttccact gaccaccgtc gtgccagtaa
    30001 cgagctacga cagagtagtg ccagtgatcg tagttcagag ccagaatatg gctggaagcg
    30061 atagagttat tagtacgggt cttaataccg ttgattgcgt taccgctgtc atcccctaaa
    30121 tcggaacccc agtcgaagtt ggtgaagccg atgtagctca gctgaccgcc ccacagatcg
    30181 gtaatcggca caaagtattt aattttgaaa cggtaaccgt cccactcgtt ttcgttcgct
    30241 gcgccatagt tctgccactg gtatttcgca tagacgttca tggacaggct catcggcagg
    30301 ccagtgtcga tatcggtacc cagacccatg taccaggtgc tctggcgacc atctttatta
    30361 cgacccatgt cgtaaatgta gttgttcgcg aagtaccact ctttgaacgg accgaagcta
    30421 aggtcagtat tggtcagctt gtcgatggag aaacgtggtt cgatttccat aaacagcgga
    30481 gaaccgtggt tccagatacc tttagcatcg gagttaccgc cgaagaatac cggcgcatcc
    30541 gcataaccat agaagtcgaa ccagtctttt ttagcgaatg cttcgtactc aaggtaggta
    30601 tcgttgcgga tctgcggtcc gaaacgggtg tgatagcttc cgacaacgtt aacgctctgg
    30661 tgccaccagt cggaaagata ctgcggtttg tcgttttcag ctgcgttgac agtaaaagac
    30721 gaagagagcg ccagtaccgc accggctgcc agtaatgttt ttttcatatg tatgccactg
    30781 tttgaaaatc ccttgcggga gtgaaaaagg cgcaaattgc gtttctaaat atttcgtata
    30841 cagaggagcc tattataaaa atcattgctc acaaaaatat gtttcgtttc acagttctat
    30901 catttacgta atcgattgcg ttcacgttta cacacattcg ggcggggatt gtactgactt
    30961 tcgcccttgt tgcaaacttt tactatcaat ccaggtgatg taagcagagt aacaaaatga
    31021 cggggaaaga tgttgcggga cgcacaaaat cgtcccgaaa tacgtttact gcataacagg
    31081 ttgaatgtcg tggatacgta caaagcctaa ctgatccaca gaaatcccct ttaactgtaa
    31141 cggaatatca acatcgctgg gggcgaggac gctggcaggg gcattaatca attgattctg
    31201 cacattgatt tcctgaaagt tgtctattgt tccctgaatt tgcccatatt caacagttcc
    31261 gctgaatgcg ggcaagggat cattcgactc accctgaata cgtagtgtaa gggtggtgcc
    31321 atctgcatca ggcgtaatat tcaccagcga catacgtaaa gtaccgatct ggctttccag
    31381 tcttgccggt gttttcgctc caggcagaag gtaaacccca ctgctggatt ttgcattcag
    31441 cctgttttgc tgagtgattt tgactgtttc ttgattgagt tgcgtcatct cctggttcag
    31501 cgtgctgacg ctgtgtttca tctgtcgcac ttcactttgc tgcacacagg cgctaaggct
    31561 gaacaggctt cccagcagga gcagtcgaaa aacgttagta ttcataggtc gtccctttct
    31621 cgtcgcaatt agcctaatgg tagagggtaa aagcagcgaa agcatcgatc ctttatctca
    31681 aaagcgttgc gcctttgttg tatcgtcagt tcagggtaaa atagatttcc gttaaccacc
    31741 tggtcaggac gccgtatgca ttgcccattc tgtttcgccg tggacactaa ggtaattgac
    31801 tctcgtctcg tgggcgaggg ttcatccgta cgccgccgtc ggcagtgtct ggtgtgtaat
    31861 gaacgtttca ccacctttga agtggcggag ctggttatgc cgcgtgttgt aaaaagcaac
    31921 gacgtgcgtg aaccgtttaa tgaagagaaa ttgcgtagcg gaatgctgcg ggcgctggaa
    31981 aaacgtccgg tgagttccga tgacgtcgaa atggcaatca atcatattaa atcgcagctg
    32041 cgcgccaccg gtgagcgcga agtgccgagc aagatgattg gcaatctggt gatggagcaa
    32101 ttgaaaaagc tcgataaagt cgcctatatc cgttttgcct ctgtctaccg cagtttcgaa
    32161 gatatcaaag aatttggcga agagatcgcg cgcctggagg actaagccgt gcaggacgag
    32221 tattacatgg cgcgggcgct aaagctggcg caacgaggac gttttaccac gcatcccaac
    32281 ccgaatgtcg ggtgcgtcat tgtcaaagat ggcgaaattg tcggtgaagg ttaccaccaa
    32341 cgtgcgggtg aaccacatgc cgaagtacac gcgttgcgta tggcgggtga aaaagccaaa
    32401 ggtgcgaccg cctatgtcac actcgaaccc tgtagccatc atggtcgtac gccaccgtgc
    32461 tgtgacgcac tcatcgccgc tggcgtagcg cgcgtggttg cctcgatgca agatcctaac
    32521 ccgcaggtcg ctgggcgtgg actttaccgt ctgcaacagg ctggcattga cgtcagccac
    32581 ggcctgatga tgagtgaagc cgagcaattg aataaaggct ttctcaagcg gatgcgcacc
    32641 ggctttcctt atattcagtt aaaacttggc gcatcgcttg atggtcgcac ggcgatggcg
    32701 agcggcgaaa gccagtggat cacttcgccc caggcgcggc gtgatgtaca actactgcgc
    32761 gcgcaaagtc atgccatttt aaccagcagc gccacggtgc tggcggatga tcctgcctta
    32821 acggtgcgtt ggtctgaact ggatgaacaa actcaggcgc tctatccgca acaaaatctc
    32881 cgtcagccga tacgtattgt gattgatagc caaaatcgcg tgacgccggt acatcgcatt
    32941 gtgcagcagc ccggcgaaac ctggttcgcg cgtacgcagg aagattctcg tgagtggccg
    33001 gaaacggtgc gtaccttgct gattccagag cataaaggtc atctggatct ggttgtactg
    33061 atgatgcaac tgggtaaaca gcaaattaac agcatctggg tggaagcggg gccaacgctc
    33121 gctggcgcat tgctgcaggc gggtttagtc gatgagctga ttgtctatat cgcacctaaa
    33181 ctattaggca gcgacgcccg cggattatgc acgctgccag ggcttgagaa attagccgac
    33241 gccccccaat ttaaattcaa agagatacgt catgtaggcc cggatgtttg cctgcattta
    33301 gtgggtgcat gatctcccgg ctcgaaaggg aagcagcgca cgaaatatta tgctaaaatc
    33361 cgcccccctg cggggccata ctcgaacccg aaggaagaaa atgaacatta ttgaagctaa
    33421 cgttgctacc ccggacgctc gcgtcgccat caccatcgcg cgtttcaaca actttatcaa
    33481 tgacagcctg ctggaaggtg caattgacgc actgaaacgt atcggtcagg taaaagatga
    33541 aaacattacc gttgtttggg tgcctggtgc ctatgagctg ccgctggcgg cgggtgcact
    33601 ggctaaaacc ggtaaatacg acgcggtgat tgcgctgggt acggttattc gtggtggcac
    33661 tgcccacttt gaatatgtcg ctggtggtgc aagcaacggc ctggcgcatg ttgcccagga
    33721 cagcgaaatt ccggttgctt ttggggttct gaccactgaa agcattgaac aagcgatcga
    33781 acgtgctggc accaaagctg gcaacaaagg tgcagaagct gcactgaccg cgcttgaaat
    33841 gattaatgta ttgaaagcca tcaaggcctg aaattagtaa ggggaaatcc gtgaaacctg
    33901 ctgctcgtcg ccgcgctcgt gagtgtgccg tccaggcgct ctactcctgg cagttgtccc
    33961 agaacgacat cgctgatgtt gaataccagt tcctggctga acaggatgta aaagacgttg
    34021 acgtcctgta cttccgtgag ctgctggccg gggtggcgac taataccgca tacctcgacg
    34081 gactgatgaa gccatacctg tcccgcctgc tggaagaact gggacaggta gaaaaagcag
    34141 tactgcgcat tgcgctgtac gaactgtcta aacgtagcga tgtgccatac aaagtggcca
    34201 ttaacgaagc gatcgaactg gcgaaatcgt tcggcgcaga agacagccat aagttcgtca
    34261 acggcgtact cgataaagca gcacctgtga ttcgccctaa caaaaagtga tatccaggcc
    34321 ggtagattca cggaagaccg ttccatgatc gccggccttt tcttttttac ctgctgaggc
    34381 ataacgtatg gcatgtggcg agttctccct gattgcccgt tattttgacc gtgtaagaag
    34441 ttctcgtctt gatgtcgaac tgggcatcgg cgacgattgc gcacttctca atatccccga
    34501 gaaacagacc ctggcgatca gcactgatac gctggtggcg ggtaaccatt tcctccctga
    34561 tatcgatcct gctgatctgg cttataaagc actggcggtg aacctaagcg atctggcagc
    34621 gatgggggcc gatccggcct ggctgacgct ggcattaacc ttaccggacg tagacgaagc
    34681 gtggcttgag tccttcagcg acagtttgtt tgatcttctc aattattacg atatgcaact
    34741 cattggcggc gataccacgc gtgggccatt atcaatgacg ttgggtatcc acggctttgt
    34801 tccgatggga cgagccttaa cgcgctctgg ggcgaaaccg ggtgactgga tctatgtgac
    34861 cggtacaccg ggcgatagcg ccgccgggct ggcgattttg caaaaccgtt tgcaggttgc
    34921 cgatgctaaa gatgcggact acttgatcaa acgtcatctc cgtccatcgc cgcgtatttt
    34981 acaggggcag gcactgcgcg atctggcaaa ttcagccatc gatctctctg acggtttgat
    35041 ttccgatctc gggcatatcg tgaaagccag cgactgcggc gcacgtattg acctggcatt
    35101 gctgccgttt tctgatgcgc tttctcgcca tgttgaaccg gaacaggcgc tgcgctgggc
    35161 gctctctggc ggtgaagatt acgagttgtg tttcactgtg ccggaactga accgtggcgc
    35221 gctggatgtg gctctcggac acctgggcgt accgtttacc tgtatcgggc aaatgaccgc
    35281 cgatatcgaa gggctttgtt ttattcgtga cggcgaacct gttacattag actggaaagg
    35341 atatgaccat tttgccacgc cataaagatg tcgcgaaaag tcgcctgaag atgagtaatc
    35401 cgtggcatct acttgctgtc ggattcggaa gtggattaag cccgatcgtt cctgggacga
    35461 tgggctcgct ggcagcgatt ccgttctggt atctgatgac ctttttgccc tggcagctct
    35521 actcgctggt ggtgatgctg gggatctgta tcggcgtcta tctttgtcat caaacggcga
    35581 aagacatggg tgtgcacgat catggcagca ttgtctggga cgaatttatt ggtatgtgga
    35641 tcacgctcat ggcgctgccg accaatgact ggcagtgggt tgccgccggg tttgtgattt
    35701 tccgtattct ggatatgtgg aagccgtggc cgatccgctg gtttgatcgc aatgtgcatg
    35761 gcggcatggg gatcatgatc gacgatattg tcgccggggt gatttccgca ggcatcctgt
    35821 attttatcgg tcatcactgg ccgctgggta ttctgtcgta gttgtgcacc gatgcctgat
    35881 gtgacgcttg tcacgtctca tcaggcctgg actcttattt aaatcctacg acaggatgcg
    35941 gtttatacgg cgtttccagt tcggcaatct gttccggctt caaagtgata tccaccgcgt
    36001 tcaatagctc atcaagctgt tcttcgcgcg aagttccgat aatcggtgcg gcaatgcccg
    36061 gtttactcaa caaccaggcc agcgcaactt gtgctcgtgt cgcccccagt tcttcactga
    36121 cgcctgttaa ccgctctgcg atctgcgcgt cattttcatc gctttcttta tagagatttt
    36181 tccccacctc atcagacacc agtcgtgcgg tagtttctcc ccacggacgc gtcagacggc
    36241 cccttgccag cgggctccat ggaattaccg ccacgccctc ctgataacac agtggtagca
    36301 tctcgcgctc ttcttcacga taaatcagat tgtagtgatc ctgcatactg acaaactgcg
    36361 cccagccgtg ctgtttttgg agttccagtg cctgagcaaa ctgcgaagcg tgcattgatg
    36421 acgcgccgat ataacgcgct ttcccggctt ttaccacgtc gttgagggct tccagcgtct
    36481 cttcgatcgg cgtgttgtaa tcccagcgat gaatttgcag gatatcgaca taatccatgc
    36541 cgagacgtcg caggctgtcg tcgatagagc gcaaaatttg cgcacgggat aatccttccg
    36601 gtaaatcacc aacgcgatgg aacactttgg tcgcaacgac cacgtcttca cgacgggcga
    36661 aatcccgcag tgcgcgaccg acgatctctt cgctgctgcc gtcagaataa ctgttggcgg
    36721 tatcaaagaa atttatgccg ccttccagtg cacgtttaat tatgggacgg ctgctttctt
    36781 ccggcagtgt ccatgcgtga ttaccgcgat ctggctcgcc aaaggtcata cagccgaggc
    36841 aaagtcggga aacgcgaagg tcggtttttc ctaaggggtt gtattgcatg ctgccactcc
    36901 tgctatactc gtcatacttc aagttgcatg tgctgcggct gcattcgttc accccagtca
    36961 cttacttatg taagctcctg gggcttcact cgtttgccgc cttcctgcaa ctcgaattat
    37021 ttagagtcta tgaataattt cttaagcata gcaggagtgg agtagggatt atgccagcca
    37081 ggccttgatt ttggcttcca taccagcggc atcgaggccg agttcggcgc gcatttcttc
    37141 ctgagttcct tgcggaataa agaagtccgg caggccaatg ttcagcacgg gtactggttt
    37201 acgatgggcc atcagcactt cgttcacgcc gctgcctgcg ccgcccataa tggcgttttc
    37261 ttctacggtg accagcgctt catggctggc ggccatttcc agaattaacg cttcatcaag
    37321 cggtttcaca aaacgcatat cgaccagcgt ggcgttcagc gattcggcga ctttcgccgc
    37381 ttctggcatc agcgtaccaa agttaaggat cgccagtttc tcgccacgac gcttcacaat
    37441 gcctttgcca attggtagtt tttccagcgg cgtcagttcc acgccgaccg cgttgccacg
    37501 cgggtagcgc accgctgacg ggccatcgtt atagtgatag ccggtataga gcatctggcg
    37561 acattcgttt tcatcgctcg gggtcataat gaccatttcc ggtatgcagc gcaggtaaga
    37621 gagatcaaaa gcaccctgat gggtttgacc gtcagcacca acaatgcccg cgcggtcgat
    37681 ggcgaacagg accggaagct tttgaatcgc cacgtcatgc agcacctgat cataggcgcg
    37741 ttgcaggaaa gtggagtaaa tcgcgacaat gggtttgtac ccaccaatcg ccagacccgc
    37801 agcaaaggtc accgcgtgtt gctcggcaat tgccacgtcg aagtagcgat ccgggaattt
    37861 acgtgaaaac tcgaccatgc cggaaccttc acgcatcgcc ggagtaatcg ccatcagctt
    37921 gttgtctttc gctgccgttt cgcacaacca gtcgccaaag atttttgaat agctcggcaa
    37981 accgccgcta cttttcggca aacaaccgct ggagggatca aatttaggca cggcgtggaa
    38041 agtgatcggg tctttttctg ccggttcata accacgacct tttttggtca tgatatgcag
    38101 gaactgcggg cctttcaggt cgcgcatgtt ctttagcgtg gtgataagcc ccagcacatc
    38161 gtgaccgtcc accgggccga tgtagttaaa gcccagctct tcaaacaacg tgccaggcac
    38221 taccatgcct ttaatatgtt cttcggtgcg tttgagcagc tctttaattg gcggcacgcc
    38281 agagaaaact tttttcccgc cttcgcgcag tgaagagtaa agcttaccgg aaagcagctg
    38341 tgccagatgg ttgttgagcg cgccgacatt ttcggaaatc gacatttcat tgtcgttgag
    38401 aatcaccagc atatcaggac ggatatcgcc cgcgtgattc atcgcttcaa acgccatgcc
    38461 tgcggtaatc gcgccatcgc caatgacaca gacggtgcgg cgatttttgc cttctttttc
    38521 ggcagcaacc gcaataccaa ttccggcact gatggaggtt gatgaatgcc cgacgcttaa
    38581 tacgtcatat tcgctttcgc cgcgccacgg gaacgggtgc agaccgcctt tctgacggat
    38641 ggtgccgatt ttgtcgcggc gtccggtcaa aattttatgc ggataagcct gatgccccac
    38701 atcccaaatc aattggtcaa acggggtgtt gtagacatag tgcagcgcca cggtcagttc
    38761 gaccgtgccc agcccggagg cgaagtgccc gctggaacgg ctcacgctgt cgagtaaata
    38821 gcggcgcagt tcgtcgcaga gtttcggtaa actctctttc ggcaacagtc gtaactcctg
    38881 ggtggagtcg accagtgcca gggtcgggta tttggcaata tcaaaactca tcaggggcct
    38941 attaatactt attgtttatt tattacgctg gatgatgtag tccgctagcg cttccagtgc
    39001 cgaggtatcg agtgactgtt cagccagttg tttcagcgac tgacgggcat cgtcgatcag
    39061 atcccgggct ttcttccggg cttgctcaag acccagaagt gcagggtagg tacttttacc
    39121 aagttgctgg tcggcaccct ggcgttttcc caacgttgca gtatctccca ccacatccag
    39181 gatgtcatcc tgaacctgga aggcaaggcc gatgctctct gcatacttgt cgagtaccgg
    39241 cagagcacga cgtcctttat ctccggcgct taatgcacca aggcgaacgg cggcgcgaat
    39301 caatgcgccg gttttatgac gatgaatacg ctcaagcgcg tccagaggta cgtgtttgcc
    39361 ttccgcgtct aaatctaatg cctgaccacc gcacattccg gcaataccac tggcgctcgc
    39421 cagttcagaa atcatcgaaa ttctgtcgcg gtccgacact tccggcatat cggcatcgct
    39481 taaaatcgag aacgccagcg tttgtaaagc gtcgccagcg agaatcgcgt ttgcttcgcc
    39541 aaacttcaca tggcaggttg gcaaaccgcg acgcagatcg tcatcatcca ttgccggtaa
    39601 atcatcatga attaatgagt aagcgtggat acactcaacg gcggcagcgg gtgcgtccag
    39661 cgtgtttgtg ctaacgccga acatatgacc ggtggcataa accaggaaag gtcgcaggcg
    39721 cttaccacct aataatgcgc catactgcat ggtttcgacc acgggagtgt tctgaaaggg
    39781 cagtggggcg ataaaacggc tcagcgcctg gttggcctgc ttaacgcagg cttcgagttg
    39841 ctgcggaaag tccattactc attgtccggt gtaaaagggg ttagagaggc gtcttcattg
    39901 tcagacagca gaatttgtac gcgctgttcg gcttgttgta atttggcctg cccctgacgt
    39961 gccagctgca cgccgcgttc gaactcgttc agcgcctctt ccagcggcag gtcgccactt
    40021 tccagacggg ttacaatctg ttccagctcg ctcagcgcct tttcaaagct ggcgggcgcc
    40081 tcatttttct tcggcataat gaatgtctga ctctcaatat ttttcgcccc gtcatggtaa
    40141 cggactcagg gcaaatagca aataacgcgc aatggtaagg tgatgtgcac agcaaagcga
    40201 tgttagtggt atacttccgc gcctggatgc agccgcaggt gtgggctgct gtatttttcc
    40261 ctatacaagt cgcttaaggc ttgccaacga accattgccg ccatgaagtt tatcattaaa
    40321 ttgttcccgg aaatcaccat caaaagccaa tctgtgcgct tgcgctttat aaaaatcctt
    40381 accgggaaca ttcgtaacgt tttaaagcac tatgatgaga cgctcgctgt cgtccgccac
    40441 tgggataaca tcgaagttcg cgcaaaagat gaaaaccagc gtctggctat tcgcgacgct
    40501 ctgacccgta ttccgggtat ccaccatatt ctcgaagtcg aagacgtgcc gtttaccgac
    40561 atgcacgata ttttcgagaa agcgttggtt cagtatcgcg atcagctgga aggcaaaacc
    40621 ttctgcgtac gcgtgaagcg ccgtggcaaa catgatttta gctcgattga tgtggaacgt
    40681 tacgtcggcg gcggtttaaa tcagcatatt gaatccgcgc gcgtgaagct gaccaatccg
    40741 gatgtgactg tccatctgga agtggaagac gatcgtctcc tgctgattaa aggccgctac
    40801 gaaggtattg gcggtttccc gatcggcacc caggaagatg tgctgtcgct catttccggt
    40861 ggtttcgact ccggtgtttc cagttatatg ttgatgcgtc gcggctgccg cgtgcattac
    40921 tgcttcttta acctcggcgg cgcggcgcat gaaattggcg tgcgtcaggt ggcgcattat
    40981 ctgtggaacc gctttggcag ctcccaccgc gtgcgttttg tcgctattaa tttcgaaccg
    41041 gtcgtcgggg aaattctcga gaaaatcgac gacggtcaga tgggcgttat cctcaaacgt
    41101 atgatggtgc gtgccgcatc taaagtggct gaacgttacg gcgtacaggc gctggtcacc
    41161 ggcgaagcgc tcggccaggt gtccagccag acgctgacca acctgcgcct gattgataac
    41221 gtctccgaca cgctgatcct gcgtccgctg atctcttacg acaaagagca catcatcaac
    41281 ctggcccgcc agattggcac cgaagacttt gctcgcacga tgccggaata ttgtggtgtg
    41341 atctccaaaa gcccgacggt gaaagcagtt aaatcgaaga ttgaagcgga agaagagaag
    41401 ttcgacttca gcattctcga taaagtggtt gaggaagcga ataacgttga tatccgcgaa
    41461 atcgcccagc agaccgagca ggaagtggtg gaagtggaaa ccgtcaatgg cttcggcccg
    41521 aacgacgtga tcctcgatat ccgttctatc gatgaacagg aagataagcc actgaaagtc
    41581 gaagggattg atgtggtttc tctgccgttc tataaactga gcaccaaatt tggcgatctc
    41641 gaccagaaca aaacctggct gctgtggtgt gagcgcgggg tgatgagccg tctgcaggcg
    41701 ctctatctgc gcgagcaggg ctttaacaat gtgaaggtat atcgcccgta atttgtggtt
    41761 tttacgtcgc atctggtcag atgcgacgtt tgccgcatcc gacactactc gtaataatta
    41821 taaatccctg ccgccatcac cagttgtgat gccacttcat gggctttttc acgcccaacc
    41881 aacaggtcga taattttcag accaaagtcg atagctgtac ccggcccctg gctggtcagc
    41941 aattttaccc gtgcatccca gacgacgcgc ttgtccagcc attgttcggc gggaattttg
    42001 tctttcagcg tcgggaagcc ggtcatatta ccaatcggga agatatcgtg cggcaccagc
    42061 acggtggctg gcgcggcgca aatagccgcg acgatacgcc cggaacggtg gaactgttta
    42121 acggtttcaa ccagcagagt gctatcgcga aaacactccg cgcctttaat gccaccaggc
    42181 agcacgatca cgtcatattc gccatcagcc acttcgacca gcggcgcatc cgccagcagc
    42241 ttcacgccgc gcgagcaggt aatcgccagg ttaccatcgc tggcgacgct ggcagtggtg
    42301 actttgatac cgccgcgaac cagcagatcg atagtggtga cggcttcagt ctcttcacta
    42361 ccaggggcga ggcaaaccag tgccgatgcg ctcatattca ctctcctttc tttttaccat
    42421 ttcaaacagg cgggtgtttt ccggtacggc aatcccatgc gcgcgggcgc ggcgtaagag
    42481 aaaaccattg atatagtcga tttcagtgtg gcgcagcgcg cggatatcct gcaacatcga
    42541 cgagatattt tccgctgtgg catcaatcac ctgcatcacg taatcacgca aatcttctgc
    42601 tgaagtatga tgcccttcgc gttcgatcac cgccgcgact tcttcgcata tctgcataat
    42661 ttcttgcgga tgatgacgta attcaccgtt cgggcaattc cagatggcag tcagtggatt
    42721 aatcacgcag ttgactgcca gcttgcgcca cagctcggcg cgaatattgt tatgccaggc
    42781 aacgtcaggc aacacggttt gcaaaatatc cgccagataa ctgtaatccc cgtcctgttg
    42841 ccgtgccggg ccaatatgcg tgataccgtt tgccacatga ataatgacat tgccgtcgcg
    42901 gcgggctgca tgggtggtgg tgcccatcag taatggctgc tgaatgtttt gcaactcttc
    42961 gatggtgccc atgccgttgt gaattaacag tattggcgta gttacaggca gtgtggacgc
    43021 gaggcttttg acggcatcgg aaacctgcca tgctttcagc gtcaccagga gcagatcgct
    43081 ggtggcgaga aaatcgggat cgttggcggt cagcgattcg ttaaatatcg aaccatctgt
    43141 ctcaaccaga ttcacgctac aataaggttg cggtacgcgc agccagccct gaacttcatg
    43201 accctgtttg caaagtgctg taagccataa ttgccctaag gcaccgcatc ccaatacggt
    43261 aattttcatt gttcctcctc acccgcaacc actccgggtg ttcaataagg ctatccctta
    43321 attgtgcatg ctgttgcgac tatgcacaat taagggatac gtcctggtgc aggactgtcg
    43381 gttatttaac tttgcgggta ttatgcttcg catcaaaaat gaagggagag gaaaagatgc
    43441 catctttcga tattgtctct gaagttgatc ttcaggaagc acgtaacgcg gtcgataacg
    43501 cgagccgcga agtggagtcc cgttttgact tccgtaacgt tgaagcctca tttgagctga
    43561 acgacgccag caaaaccatc aaagtgttga gcgagtccga tttccaggtc aatcagttgc
    43621 tggatattct gcgtgccaag ctgctgaagc gcggcattga aggcagttcg ctggatgtac
    43681 cggagaatat cgttcatagc ggtaaaacct ggtttgtgga agcgaaactg aaacagggca
    43741 ttgagagcgc gacccagaag aaaatcgtca agatgatcaa agacagcaaa ctgaaagtgc
    43801 aggcgcaaat tcagggcgat gaaatccgcg taacgggcaa atctcgtgat gatttgcagg
    43861 ctgtcatggc gatggtacgt ggtggcgatc tcggtcagcc gttccagttc aaaaacttcc
    43921 gcgattaatc gcgactatgt gcgttttgtt catgtcagat gcggcatgaa cgcctgattc
    43981 ggcctacaaa ggtttgtaat tcagaaactt tgtaggcctg ataagcgtag cgcagcaggc
    44041 aattcgccgc gttttttatg cctgacgaat tgcctgttct atctcaaagc gattcgtcac
    44101 tttgctgtcg attttcacat aagctgaatg ttcttcttct gcaatcaaca cttctttgat
    44161 gccttcagtt tctagcaaac gcacttttaa cgcctcgttt gcggcaatgt tcgccgggat
    44221 ttcaatgcgc aaactgctga catacggcgg ttctttcatg gtactggcga ctgtcagcca
    44281 cactgcggcc agcattgcgc cagcgagaaa taccccctga ccgtcaaaca tgccgttaat
    44341 ccagccgccc agcgaaccgc caatcgccac gccaagaaac tggctggtgg agtaaacacc
    44401 catcgccgta cctttgtaac ctgctggcga ctctttactg ataagtgagg gcaggagggc
    44461 ttccatcaaa ttaaacgcca caaagaaaag ctgcacgccg accaccagtt gccagaactg
    44521 cgtttgtgcg ttccacaaca caatttccgc aaccacgatc aacccgacgc agaagacaaa
    44581 gacttgcttc attttgcgct taacttcagc gtagataatg aaaggcacga ccgagccaaa
    44641 ggcgattagc attgtcgcca gatagacctt ccagtgttca gccgccggga accctgcatc
    44701 agccagttgt ccgggcaggg caacaaacgt cgacatcagc aaaatatgca gacacataat
    44761 gccaaagttg agtttcagca gccgcggttc cgccagcact ttactgaaac tgcctttcac
    44821 cattccggac tcacgattaa gtacgtgagt gctactgttg ggcacaaccc aaatggtcaa
    44881 cgcaatgccg gtcgttgcca gaatagcgat catccagaac agcgcgtgca gcccaagttt
    44941 gtgagtgatg atcgggccaa gcaccatcgc aatggcaaag gtaatgccaa agctcacgcc
    45001 gataaacgcc atcgctttgg tgcggttttg ttcgcgcgtg agatcggaaa gcagcgccat
    45061 aacggcggcg gcaattgctc cagagccttg tagcgcccgg cccagaataa ttccccagat
    45121 ggagtcggaa agcgcagcga taacgctacc ggcggcaaac accgccagcc caccgacaat
    45181 taatggtttg cgaccaatgc ggtcggaaag caggccaaac ggaatctgaa aaacggcctg
    45241 agtcagacca taaataccaa tggcaatacc gattaatgct tcgctggcac cttgcagagc
    45301 catgccgtac gtggtcagaa ccggcagaac cataaacatg cccagcatgc gcaacgagaa
    45361 tacggtccct aaaccccagg tcgcgcgcct ctcacctggc gtcattttat aatcgttcat
    45421 taccacctct gttttaaatt cgcgactagt gtaaagcggc aaacgaatgg ggtaaacatg
    45481 cggatttttt agtaaatatt tcgagaggga tatgtttcta atgctaagaa aaaaggtgcc
    45541 gtagcacctt tttaatagag aggttttgtt accacacagc agccagcagc gtatgcgagt
    45601 ccggtaccat aaaatcaacg gacatcatca ccgagagggc agtgatggcg atgatagaga
    45661 agccgaacag cttgcgcgcc cagattctgt catcagcaac tttataaccg cgcagagcca
    45721 tacctaacca ccagacgcta accgccgcgg cgaccaccag atatttatac ccagcgtaac
    45781 cgccaagaga gagcatcagc gtggcaacgg caaaggcgat gatatacagc gtgatgtgat
    45841 tcttcgccac cgaaatgcct tttaccactg gcaataccgg aatgtttgcc gcctggtaat
    45901 ccttaaagcg gaaaatggcg atggcatagg agtgaggcat ctgccacagg ctgaagatag
    45961 ccagcaggat cgctgcgccg ctatcgaact caccggttac cgcacagtag ccgatcaccg
    46021 gcggcgcagc gccggagagc gaaccaatca acgtgccgta gacagagtgg cgtttcatgt
    46081 acaggctata aacgccgaca taaaccacaa agcccatcac ccccagccag caggccagcg
    46141 gattcgcgcc aaaccacagc agcataaagc cagcaatacc cagcaacgtg gcgtacacca
    46201 gcgagacagc aggagagatc aggcctttca ccagcacccg attcttcgtc ctttccatct
    46261 ttctgtcgat atccctgtcg atgtagttgt taaacacaca acccgacgcc acaaccagtg
    46321 acaccccaac cagcgtgtag ataaacaggg gataatcaat gctgcccttt gaggccagca
    46381 ggaatccccc aatcaccgag atcaggttgc caaagatgat gcctggtttc gttacttgca
    46441 ggtattgctt aaacatcata accgccgctc ttagtgcatc atcatgttgt agttgaggtt
    46501 ccacataatc cagatggagc ctacaaccag gatagcgatg attagcacgg tgaagacaaa
    46561 cgccgtcatg ttccagcctt catctgattt ggtattcatg tgcaggaagc acaccagatg
    46621 caccagaacc tgtaccactg ccattgccag gattgttccc agaattacgg ccggagaggc
    46681 agctcctgtc atcaccatcc agaacggaat caccgtcaga atgatcgaca ggataaagcc
    46741 tgtcatgtag gtttttacgc tgccatggga cgcgccgctg tgatcggtag aatgactcat
    46801 tacatcgccc ccatcagata aacaacagtg aacacacaga tccaaaccac atccaggaag
    46861 tgccagaaca ggctcaggca catgatgcgg gtacggttag tgctggtcag gccgcgacgg
    46921 gcgatttgca ccatcagcac cgccatccag ataagaccag aagtgacgtg cagaccgtgc
    46981 gtgccgacca gcgcaaagaa cgctgacagg aagccgctgc gatccggacc catgccgtta
    47041 acaatcaggt gatggaattc atagatttcc atcccgataa atccggcacc aaacaaccag
    47101 gtcaacgcca gccaggagat aacctggctt ttgttgtttt tgtacatggc gatagccgcc
    47161 atgccgtagg tgatggagct gaacaacagc aagaaagttt caaccagaac gaacggcagt
    47221 tcgaaaatgt ccttacctgt cgggccgcct gcggtgccgt tcaccagaac ggcataggta
    47281 gcaaacaaga tagagaacag aatgcagtcg ctcatcaggt agatccaaaa tccgaagatt
    47341 ttggttccgc ctgcatcgtg gtgcccgtgt tcgtgcgcgt gggcagtcgc gtgcgtcaaa
    47401 gtatcagttg ccatttttca gccctgcctt agtaatctca tcgaaatgct ggttttccag
    47461 tttttcgatt tctgccaccg gcacgtagta atccacgtcc tcgtcgaagc ttttcacgat
    47521 ccaggtgatg atcatgcctg cgaagccaac aatcgccagc caccagatat gccagatcat
    47581 ggcgaaaccg aagatggtgg agaaagctgc aatgacgata cctgcaccgc tgtttttcgg
    47641 catatgaatt tcttcatagt ggtcaggctt tttatacgct tcgcctttct ctttcatttc
    47701 ccagaatgca tcacgttcgt gaacgtgcgg cactacggca aagttataga acggaggcgg
    47761 ggaagaggtt gcccactcca gcgtacggcc accccacggg tcgccagtca ggtcacggtt
    47821 ctggtcgcgg tcgcgaatag aaacgtacat ctgaataacg aggcagagaa tacccagcgc
    47881 aatcagtact gcaccgctgg ctgcaatcat cagcatggtg tggaactgcg ggtcaatctg
    47941 ctggctcaaa cgacgggtca tgcccatgaa gcccagcgca tacagtggca taaaggcaac
    48001 gaagaagccg atgatccaga accagaacgc gcgtttaccc caggtttcgt tcagtttgaa
    48061 accgaacgct ttaggccacc agtaggtcat ccctgcgaag cagccgaaga ccacgccgcc
    48121 gatgatcacg ttatggaagt gcgcaatcag gaacaggctg ttatgcagaa cgaagtccgc
    48181 gcccggtacg gccagcagca cgccagtcat cccgcccacc gagaaggtga cgataaaacc
    48241 gatggtccac agcatcgcag aatggaacac gatgcggccc tgatacatgg tgaacagcca
    48301 gttgaagatc ttcaccccgg tcgggatggc gataatcatt gtggtgatac caaagaaggc
    48361 gtttacgttc gcgcccgcac ccatcgtaaa gaagtggtgc agccaaacga tgaacgacag
    48421 cacggtgata cagacggttg cccataccag cgaggtataa ccaaacagac gtttacgcga
    48481 gaaggttgcc gcaatttcgg agaacacacc gaaaacaggc aggatcagga tgtaaacttc
    48541 cgggtggccc caggcccaaa tcaggttgat gtacatcatc atgttgccac ccatatcgtt
    48601 ggtaaagaaa tgggtgccca gatagcgatc cagggtcaac aacgcgacgg taaccgtcag
    48661 aattgggaag gaagcaataa tcagtacgtt cgcgcacagt gatgcccagg taaatactgg
    48721 catcttgaac atggtcatgc ccggtgcgcg catcttcaga atggtaacga agaagttgat
    48781 accggtaagc gtcgtaccta taccggatag ctggagactc catatccagt aatcgacacc
    48841 gactcccgga ctgtactcta ttcccgatag cggtggatag gccagccagc cggtctgcgc
    48901 aaattcgccc acgccgagag aaacgttaac cagaatcaca ccaacaacgg taaaccagaa
    48961 gcttaagttg ttgaggaacg ggaacgcaac gtcacgcgcg ccgatctgca gcggaaccac
    49021 caggttcatc agaccgataa cgaaaggcat cgccacgaag aagatcataa tcacgccgtg
    49081 cgcggtaaag atctgatcgt agtggtgagg tggcaggaag cccgcttcgc ccgccgaggc
    49141 aagagcctgc tggctacgca tcataatggc gtcagcaaaa ccacgcagca acatcacaat
    49201 cgccacgatg atatacatga taccgaggcg tttatggtcg acggaggtca gccactcttt
    49261 ccacaggtag gtccacttac cgaagtaagt gatcaggcca acgagcgcca gacctcccaa
    49321 aataatgcca gcgatcgtaa ccatgacgat aggttcatgg aacgggactg catcaagtga
    49381 taattttccg aacatcttta ttcttcctca acccctttaa tgggcggatt ccgcgtggct
    49441 catgtccatg ccttccatac cttcgtgtgc gctgtgctca ccttctggct gggtcatgtc
    49501 catgctctta ccgtgagcca taaacttgtt aattacatcg gcaaacaagt ctggtttcac
    49561 gttggagaaa tattccacct ggttgtattc gctaggcgcg gccagttttt cgaacgcagc
    49621 catgtcagac atggtgttcg gcgactgctt cgcttttgcg acccactggt cgaatgcggc
    49681 gcgatccggt gttgcaatag ctttgaactt catgcctgag aagcccgggc cgctgtagct
    49741 ggcggagata ccgtcataag tgccgggttc gttggcgatc agatgcaggc gagtctgcat
    49801 accggccatg gcataaatct ggctacccag acgcggaatg aagaaggagt tcatcacgga
    49861 gttggaggtc actttgaagt acaccggagt gttcgccggg aaagcgattt cattcacggt
    49921 agcaatgccc tgttccgggt agatgaagaa ccatttccag tccatggaaa ccacttcgat
    49981 ggtaatgggc ttctcgtcgt gtgccagcgg cttgctaggc tcaagagcgt gagtggtttt
    50041 ccaggtcagt actgcaagga agatgatgat taagataggt accgtccaga ccacagcttc
    50101 cactttattg gagtgtgacc agttcgggct gtacttagca tctttattgc tcgcacggta
    50161 cttccaggcg aaaccaacag ccatcaagat tgcgggaata acgacaatca acatcaggcc
    50221 aaatgccgtc agtatcagtg aacgttgctc cagaccaatc tgtcctttgg gatctaacag
    50281 cgcagaatta cagccactga gcaatacagt gcctgcaaat aatgacaacc atcccaaact
    50341 tttattgtat ttcctgagtc tcatttaacg acctcaattc cacgggatct ggtggcgttt
    50401 aaagtgtgtg ggcattttac gggaaggtta cattactgta aacatgatta aattcctgtt
    50461 gcttggattt ggctgccagg tcacatatgt tgcaaaacat atcaggttga ttttaagaag
    50521 ctgttgcaaa agggcgttat aacaaaaggg gagtgctgaa ggagtctggg cgggcaattg
    50581 gtataaccaa tgtgaaataa aacaattatt taacaaataa ttatcattag agtgacaact
    50641 gggtgatgag aaaataaaga ctcattagct gaatcgtgta agaaaaatag aatttataaa
    50701 tggcgccaat aatttccaaa cgctaagccg cacaaaagaa caaatattaa taagcgatac
    50761 tgatgtttat ttagccgtaa taattacggc gagtgattac tacagctaaa taatatttac
    50821 agattacgtc agatgcgttt ttcgtagcgc cagataatcc agcaaaccac caagcacgac
    50881 gccagaaagg gcgactaaaa ccccgacttc cagcagagca ggcaggaaag agaagtgcgt
    50941 caaatccagc gcgtccatcg tcaatagcag taaccacacg gccaacaggc tgacgcccgc
    51001 cgccagtgtc cacatggcaa aggcataacc tgccggatat gcggtacggg agataaagtt
    51061 gtcatttact cgtgtatatt caagcgtctg gcggcaaacc agcagcaaaa taagccctgg
    51121 tacggcagcg gcgacggaga atagatagaa tgtcgaccag ccgtgtgctt caacaaacca
    51181 acccgccacg gggccgacat aaactcgccc tacagcagaa agcgctgaga gcagggcaaa
    51241 ttgagtagcg gaaaatgact tattacatag cgtcattaac agcgcgacaa aggctgatgt
    51301 gcccatcccg ccacagaggt tttcgaaaaa gacggctgcg cccatgctgt agagatgctt
    51361 atcagtaatc gacagcagcc agtaaccggc gttagacgca ccttgtaaaa tgccgaaaat
    51421 cagcagtgcc cggaacagtg acaggcgctg catcaaaatc ccaccgtaca atgcgccaac
    51481 aatggtcgct agtaagccaa gcgttttgtt aaccacgcct acttcacccg catcaaaccc
    51541 gacgccgcga atcaaaaacg tggttgtcag gctcatggcg aatgcgtcgc ccagcttata
    51601 cagcacgata agaagcaaaa taagccaggc attattgcga ccaaagaaat ctcgcagagg
    51661 tgcaacaacc gcttgttcca gcgtttttgg cacaggaatg gtgtcggtcg gttctggtgc
    51721 aagcaacgtc gcgataatac aggggatcaa cagcgccgcc atcaaccagt acatgccctg
    51781 ccagcccagc catttatctg ccagccacag ggctaggccg ccggaaacca gcatccctaa
    51841 acggtaaccc agaacgctga ttgccgcgcc cgcaccacgt tcttctgccg ggagcacatc
    51901 ggttttccac gcatcgaaga caatatcctg ggaggcagag caaaaagcga tcaccaccgc
    51961 cagcgccgcc atccagcgga gttgggtgcc tggttcgaga aaacccatcg ccgcaatggc
    52021 gactaataac aggatttgcg tggcgagcag ccaaccgcgt cgccgcccaa aaaatggagg
    52081 cgtgtagcgg tccatcagcg gtgaccagag gaatttaaaa acgtaagcct ggcctaccag
    52141 agagaagaaa ccaatggttt tgagatcaat attctcgacc gtcatccagg cctgtaaggt
    52201 accggatgtc agggcgagcg gtagcccgga agcaaaaccc aggatcagca atatggctga
    52261 acgcggctgt tgaaaaatac gtaaatattg actggacatg ggcgtctaca ggcccggctt
    52321 gcaccgggcc agagggcaga aattaacgcg cgttctgctt gatgaattcg tggatgctgg
    52381 tgtcctgaga catatcagcg atggtatcgg tcagcacact gttaaccgca tcggcgatat
    52441 ttttgttgga ggcctggaac gcaccttcaa cgttgtagct ggcacgatag tttttggtca
    52501 ttttgttgcc attctgcgcg gtagcgatga tggcgatatc cgctttggtc gcgatgttgt
    52561 agcgcacgtt gccctgggac acgtcagcat acagttggct aacgatgatt tgcagattaa
    52621 ccgggccatt cggaccaacc atgtaaccac gcgcggtcat ctgtttttcc agcacttctt
    52681 gcagcaggaa acgcagatcg cgggaggcgg tcagggtaac gatttgatta tcgcgggtga
    52741 cttttgccag cgcctgatcg gtacgctgat cggcaccatt aatgcttacg gtgacgccca
    52801 tcaggcttgg atcctgctgt ggcagtgtaa tcgtcgggga aacttcaata gttgttggcg
    52861 gttttgcgca tcctgcaagc ataaacagag caactaacgg gaagaggatt tttttgaaca
    52921 tgttcgggct ctcagagact cttaagcgtg tttggtaaaa attcccgcca tcataacatt
    52981 gccaacggcg aggggaagtg ggtaaggcat gtaaattcat catgttgacg aaataatcgc
    53041 ccctggtaaa agaaacactg atgcgaggcc tgtgtttcaa tctttaaatc agtaaacttc
    53101 atacgcttga cggaaaaacc aggacgaaac ctaaatattt gttgttaagc tgcaatggaa
    53161 acggtaaaag cggctagtat ttaaagggat ggatgacatc tcagcgttgt cggaggagat
    53221 atttcatgat gatacgtgag cggatagaag aaaaattaag ggcggcgttc caacccgtat
    53281 tcctcgaagt agtggatgaa agctatcgtc acaatgtccc agccggctct gaaagccatt
    53341 ttaaagttgt gctggtcagc gatcgtttta cgggtgaacg ttttctgaat cgtcatcgaa
    53401 tgatttacag tactttagcg gaggaactct ctactaccgt tcatgcgctg gctctgcata
    53461 cttacactat taaggagtgg gaagggttgc aggacaccgt ctttgcctct cctccctgtc
    53521 gtggagcagg aagcatcgcg taaaaacgca tttgcaactg tcggcgcttt tccagtatgt
    53581 tgctaaagat tttatgaaaa acggcctgcg ggccgttttg ttttgtctgg attttgcgct
    53641 ttttgcccag cattcagacg aaaattgccc gggaattgtg aaaaaatacg cgacagcgcg
    53701 caataaccgt tctcgactca taaaagtgat gccgctataa tgccgcgtcc tatttgaatg
    53761 ctttcgggat gattctggta acagggaatg tgattgatta taagaacatc ccggttccgc
    53821 gaagccaaca acctgtgctt gcggggtaag agttgaccga gcactgtgat tttttgaggt
    53881 aacaagatgc aagtttcagt tgaaaccact caaggccttg gccgccgtgt aacgattact
    53941 atcgctgctg acagcatcga gaccgctgtt aaaagcgagc tggtcaacgt tgcgaaaaaa
    54001 gtacgtattg acggcttccg caaaggcaaa gtgccaatga atatcgttgc tcagcgttat
    54061 ggcgcgtctg tacgccagga cgttctgggt gacctgatga gccgtaactt cattgacgcc
    54121 atcattaaag aaaaaatcaa tccggctggc gcaccgactt atgttccggg cgaatacaag
    54181 ctgggtgaag acttcactta ctctgtagag tttgaagttt atccggaagt tgaactgcag
    54241 ggtctggaag cgatcgaagt tgaaaaaccg atcgttgaag tgaccgacgc tgacgttgac
    54301 ggcatgctgg atactctgcg taaacagcag gcgacctgga aagaaaaaga cggcgctgtt
    54361 gaagcagaag accgcgtaac catcgacttc accggttctg tagacggcga agagttcgaa
    54421 ggcggtaaag cgtctgattt cgtactggcg atgggccagg gtcgtatgat cccgggcttt
    54481 gaagacggta tcaaaggcca caaagctggc gaagagttca ccatcgacgt gaccttcccg
    54541 gaagaatacc acgcagaaaa cctgaaaggt aaagcagcga aattcgctat caacctgaag
    54601 aaagttgaag agcgtgaact gccggaactg actgcagaat tcatcaaacg tttcggcgtt
    54661 gaagatggtt ccgtagaagg tctgcgcgct gaagtgcgta aaaacatgga gcgcgagctg
    54721 aagagcgcca tccgtaaccg cgttaagtct caggcgatcg aaggtctggt aaaagctaac
    54781 gacatcgacg taccggctgc gctgatcgac agcgaaatcg acgttctgcg tcgccaggct
    54841 gcacagcgtt tcggtggcaa cgaaaaacaa gctctggaac tgccgcgcga actgttcgaa
    54901 gaacaggcta aacgccgcgt agttgttggc ctgctgctgg gcgaagttat ccgcaccaac
    54961 gagctgaaag ctgacgaaga gcgcgtgaaa ggcctgatcg aagagatggc ttctgcgtac
    55021 gaagatccga aagaagttat cgagttctac agcaaaaaca aagaactgat ggacaacatg
    55081 cgcaatgttg ctctggaaga acaggctgtt gaagctgtac tggcgaaagc gaaagtgact
    55141 gaaaaagaaa ccactttcaa cgagctgatg aaccagcagg cgtaatttac gcagcataac
    55201 gcgctaaatt cgcacaaagg cccgtcaccg ccaggtggtg ggcttttttt tgtcatgaat
    55261 tttgcatgga accgtgcgaa aagcctcttt cggtgttagc gtaacaacaa aagattgtta
    55321 tgcttgaaat atggtgatgc cgtacccata acacagggac tagctgataa tccgtccata
    55381 aggttacaat cggtacagca ggttttttca attttatcca ggagacggaa atgtcataca
    55441 gcggcgaacg agataacttt gcaccccata tggcgctggt gccgatggtc attgaacaga
    55501 cctcacgcgg tgagcgctct tttgatatct attctcgtct acttaaggaa cgcgtcattt
    55561 ttctgactgg ccaggttgaa gaccacatgg ctaacctgat tgtggcgcag atgctgttcc
    55621 tggaagcgga aaacccagaa aaagatatct atctgtacat taactcccca ggcggggtga
    55681 tcactgccgg gatgtctatc tatgacacca tgcagtttat caagcctgat gtcagcacca
    55741 tctgtatggg ccaggcggcc tcgatgggcg ctttcttgct gaccgcaggg gcaaaaggta
    55801 aacgtttttg cctgccgaat tcgcgcgtga tgattcacca accgttgggc ggctaccagg
    55861 gccaggcgac cgatatcgaa attcatgccc gtgaaattct gaaagttaaa gggcgcatga
    55921 atgaacttat ggcgcttcat acgggtcaat cattagaaca gattgaacgt gataccgagc
    55981 gcgatcgctt cctttccgcc cctgaagcgg tggaatacgg tctggtcgat tcgattctga
    56041 cccatcgtaa ttgatgccag aggcgcaact gtgccgctat acttatccag ggcggcacaa
    56101 cgctgtaagc ggcttgcgcc tgagaatggc atttgcgtcg tcgtgtgcgg cacaaagaac
    56161 aaagaagagg ttttgaccca tgacagataa acgcaaagat ggctcaggca aattgctgta
    56221 ttgctctttt tgcggcaaaa gccagcatga agtgcgcaag ctgattgccg gtccatccgt
    56281 gtatatctgc gacgaatgtg ttgatttatg taacgacatc attcgcgaag agattaaaga
    56341 agttgcaccg catcgtgaac gcagtgcgct accgacgccg catgaaattc gcaaccacct
    56401 ggacgattac gttatcggcc aggaacaggc gaaaaaagtg ctggcggtcg cggtatacaa
    56461 ccattacaaa cgtctgcgca acggcgatac cagcaatggc gtcgagttgg gcaaaagtaa
    56521 cattctgctg atcggtccga ccggttccgg taaaacgctg ctggctgaaa cgctggcgcg
    56581 cctgctggat gttccgttca ccatggccga cgcgactaca ctgaccgaag ccggttatgt
    56641 gggtgaagac gttgaaaaca tcattcagaa gctgttgcag aaatgcgact acgatgtcca
    56701 gaaagcacag cgtggtattg tctacatcga tgaaatcgac aagatttctc gtaagtcaga
    56761 caacccgtcc attacccgag acgtttccgg tgaaggcgta cagcaggcac tgttgaaact
    56821 gatcgaaggt acggtagctg ctgttccacc gcaaggtggg cgtaaacatc cgcagcagga
    56881 attcttgcag gttgatacct ctaagatcct gtttatttgt ggcggtgcgt ttgccggtct
    56941 ggataaagtg atttcccacc gtgtagaaac cggctccggc attggttttg gcgcgacggt
    57001 aaaagcgaag tccgacaaag caagcgaagg cgagctgctg gcgcaggttg aaccggaaga
    57061 tctgatcaag tttggtctta tccctgagtt tattggtcgt ctgccggttg tcgcaacgtt
    57121 gaatgaactg agcgaagaag ctctgattca gatcctcaaa gagccgaaaa acgccctgac
    57181 caagcagtat caggcgctgt ttaatctgga aggcgtggat ctggaattcc gtgacgaggc
    57241 gctggatgct atcgctaaga aagcgatggc gcgtaaaacc ggtgcccgtg gcctgcgttc
    57301 catcgtagaa gccgcactgc tcgataccat gtacgatctg ccgtccatgg aagacgtcga
    57361 aaaagtggtt atcgacgagt cggtaattga tggtcaaagc aaaccgttgc tgatttatgg
    57421 caagccggaa gcgcaacagg catctggtga ataattaacc attcccatac aattagttaa
    57481 ccaaaaaggg gggattttat ctccccttta atttttcctc tattctcggc gttgaatgtg
    57541 ggggaaacat ccccatatac tgacgtacat gttaatagat ggcgtgaagc acagtcgtgt
    57601 catctgatta cctggcggaa attaaactaa gagagagctc tatgaatcct gagcgttctg
    57661 aacgcattga aatccccgta ttgccgctgc gcgatgtggt ggtttatccg cacatggtca
    57721 tccccttatt tgtcgggcgg gaaaaatcta tccgttgtct ggaagcggcg atggaccatg
    57781 ataaaaaaat tatgctggtc gcgcagaaag aagcttcaac ggatgagccg ggtgtaaacg
    57841 atcttttcac cgtcgggacc gtggcctcta tattgcagat gctgaaactg cctgacggca
    57901 ccgtcaaagt gctggtcgag gggttacagc gcgcgcgtat ttctgcgctc tctgacaatg
    57961 gcgaacactt ttctgcgaag gcggagtatc tggagtcgcc gaccattgat gagcgggaac
    58021 aggaagtgct ggtgcgtact gcaatcagcc agttcgaagg ctacatcaag ctgaacaaaa
    58081 aaatcccacc agaagtgctg acgtcgctga atagcatcga cgatccggcg cgtctggcgg
    58141 ataccattgc tgcacatatg ccgctgaaac tggctgacaa acagtctgtt ctggagatgt
    58201 ccgacgttaa cgaacgtctg gaatatctga tggcaatgat ggaatcggaa atcgatctgc
    58261 tgcaggttga gaaacgcatt cgcaaccgcg ttaaaaagca gatggagaaa tcccagcgtg
    58321 agtactatct gaacgagcaa atgaaagcta ttcagaaaga actcggtgaa atggacgacg
    58381 cgccggacga aaacgaagcc ctgaagcgca aaatcgacgc ggcgaagatg ccgaaagagg
    58441 caaaagagaa agcggaagca gagttgcaga agctgaaaat gatgtctccg atgtcggcag
    58501 aagcgaccgt agtgcgtggt tatatcgact ggatggtaca ggtgccgtgg aatgcgcgta
    58561 gcaaggtcaa aaaagacctg cgtcaggcgc aggaaatcct tgataccgac cattatggtc
    58621 tggagcgcgt gaaagatcga atccttgagt atcttgcggt tcaaagccgt gtcaacaaaa
    58681 tcaagggacc gatcctctgc ctggtagggc cgccgggggt aggtaaaacc tctcttggtc
    58741 agtccattgc caaagccacc gggcgtaaat atgtccgtat ggcgctgggc ggcgtgcgtg
    58801 atgaagcgga aatccgtggt caccgccgta cttacatcgg ttctatgccg ggtaaactga
    58861 tccagaaaat ggcgaaagtg ggcgtgaaaa acccgctgtt cctgctcgat gagatcgaca
    58921 aaatgtcttc tgacatgcgt ggcgatccgg cctctgcact gcttgaagtg ctggatccag
    58981 agcagaacgt agcgttcagc gaccactacc tggaagtgga ttacgatctc agcgacgtga
    59041 tgtttgtcgc gacgtcgaac tccatgaaca ttccggcacc gctgctggat cgtatggaag
    59101 tgattcgcct ctccggttat accgaagatg aaaaactgaa catcgccaaa cgtcacctgc
    59161 tgccgaagca gattgaacgt aatgcactga aaaaaggtga gctgaccgtc gacgatagcg
    59221 ccattatcgg cattattcgt tactacaccc gtgaggcggg cgtgcgtggt ctggagcgtg
    59281 aaatctccaa actgtgtcgc aaagcggtta agcagttact gctcgataag tcattaaaac
    59341 atatcgaaat taacggcgat aacctgcatg actatctcgg tgttcagcgt ttcgactatg
    59401 gtcgcgcgga taacgaaaac cgtgtcggtc aggtaaccgg tctggcgtgg acggaagtgg
    59461 gcggtgactt gctgaccatt gaaaccgcat gtgttccggg taaaggcaaa ctgacctata
    59521 ccggttcgct cggcgaagtg atgcaggagt ccattcaggc ggcgttaacg gtggttcgtg
    59581 cgcgtgcgga aaaactgggg atcaaccctg atttttacga aaaacgtgac atccacgtcc
    59641 acgtaccgga aggtgcgacg ccgaaagatg gtccgagtgc cggtattgct atgtgcaccg
    59701 cgctggtttc ttgcctgacc ggtaacccgg ttcgtgccga tgtggcaatg accggtgaga
    59761 tcactctgcg tggtcaggta ctgccgatcg gtggtttgaa agaaaaactc ctggcagcgc
    59821 atcgcggcgg gattaaaaca gtgctaattc cgttcgaaaa taaacgcgat ctggaagaga
    59881 ttcctgacaa cgtaattgcc gatctggaca ttcatcctgt gaagcgcatt gaggaagttc
    59941 tgactctggc gctgcaaaat gaaccgtctg gtatgcaggt tgtgactgca aaatagtgac
    60001 ctcgcgcaaa atgcactaat aaaaacaggg ctggcaggct aattcgggct tgccagcctt
    60061 tttttgtctc gctaagttag atggcggatc gggcttgccc ttattaaggg gtgttgtaag
    60121 gggatggctg gcctgatata actgctgcgc gttcgtacct tgaaggattc aagtgcgata
    60181 taaattataa agaggaagag aagagtgaat aaatctcaat tgatcgacaa gattgctgca
    60241 ggggctgata tctctaaagc tgcggctggc cgtgcgttag atgctattat tgcttccgta
    60301 actgaatctc tgaaagaagg ggatgatgta gcactggtag gttttggtac ttttgccgtt
    60361 aaagagcgtg ctgcccgtac tggccgcaac ccgcagaccg gtaaagagat caccatcgct
    60421 gctgctaaag taccgagctt ccgtgcaggt aaagcactga aagacgcggt aaactaagcg
    60481 ttgtccccag tggggatgtg acgaagttca agggcgcatc tactgatgtg ccttttttat
    60541 ttgtattcgg tgactttctg cgtcttgtgg gctgacaatt gcccccgttt cttgtcacaa
    60601 taggcctttg cgcgcatcga tacgttgcgt gaggtacaca gtcatctaca gcggagtgtt
    60661 gttacaccat gatggacagc ttacgcacgg ctgcaaacag tctcgtgctc aagattattt
    60721 tcggtatcat tatcgtgtcg ttcatattga ccggcgtgag tggttacctg attggcggag
    60781 gcaataacta cgccgcaaaa gtgaatgacc aggaaatcag ccgtgggcaa ttcgagaacg
    60841 ccttcaacag cgagcgtaat cgcatgcagc aacagctggg cgatcaatac tccgagctgg
    60901 cagcgaacga aggctatatg aaaaccctgc gtcaacaggt gctgaatcgt ctgatcgacg
    60961 aggcgctgct ggatcagtac gcacgtgagc tgaaactggg tatcagcgat gagcaggtta
    61021 aacaggcgat tttcgcgacc ccagccttcc aggttgacgg caaatttgat aacagccgct
    61081 ataacggtat cctcaaccag atggggatga ccgccgatca gtacgcccag gcgctgcgta
    61141 accagctcac tacccaacag ctgattaacg gcgttgccgg taccgatttt atgctgaaag
    61201 gtgaaaccga cgagctggcg gcactggtcg cgcaacaacg cgtggtgcgt gaggcgacta
    61261 tcgatgttaa cgcgctggcg gcgaagcagc ctgtgaccga acaggagatt gccagctact
    61321 acgaacaaaa caaaaacaat ttcatgacgc cggaacaatt ccgcgtgagt tacatcaagc
    61381 tggatgccgc aacgatgcag caaccggtta gcgatgcgga tatccagagc tactacgacc
    61441 agcatcagga tcaattcacc cagccgcagc gtacccgcta cagcatcatc cagaccaaaa
    61501 ctgaagatga agcgaaagcg gtacttgatg agctgaataa aggcggtgat tttgctgcat
    61561 tagccaaaga aaaatctgcc gatattatct ctgctcgtaa cggcggcgat atgggttggt
    61621 tagaagatgc cactatcccg gacgaactga aaaatgctgg tctgaaagaa aaaggccaac
    61681 tgtctggtgt catcaaatct tcggtcggtt tcctgattgt acgtctggac gacattcagc
    61741 cagcgaaagt gaaatcgtta gacgaagtac gtgacgacat tgcggcgaaa gtgaaacacg
    61801 aaaaagccct cgatgcgtac tacgcgctgc agcagaaagt gagcgatgcg gcaagcaacg
    61861 acaccgagtc tctggccggt gcagagcaag ctgccggcgt taaagccact cagacgggtt
    61921 ggttcagcaa agataacctg ccggaagagt tgaacttcaa gccggttgcc gacgctatct
    61981 ttaacggcgg tctggtaggt gaaaacggcg cgccgggcat caactctgac atcatcaccg
    62041 tagacggcga ccgcgcattc gtgctgcgca tcagcgagca caaaccggaa gcggtgaaac
    62101 cgttggcaga tgttcaggaa caagttaagg cattggttca gcacaacaaa gctgaacaac
    62161 aggcgaaagt ggatgctgag aaactgctgg ttgatttgaa agccggcaaa ggtgcggaag
    62221 ctatgcaggc tgccggtctg aaatttggcg agccgaaaac cttaagccgt tccggtcgtg
    62281 acccgattag ccaggcggcg tttgcactgc cactgccagc gaaagacaaa ccgagctacg
    62341 gtatggcgac cgatatgcaa ggtaatgtgg ttctgctggc gctggatgaa gtgaaacaag
    62401 gttcaatgcc ggaagatcag aaaaaagcga tggtgcaggg tatcacccag aacaacgcac
    62461 aaatcgtctt tgaagctctg atgagtaacc tgcgtaaaga ggcgaaaatc aaaattggcg
    62521 atgcgctgga acagcaataa tcctgaagcc gcctcgcaaa aaaatgcgtt gcagctgtaa
    62581 caagaaaagg tcgctttcgc ggccttttcc atttctgaac attgccattt gtttactgtt
    62641 ttcactgccg ttaaggtgat tccactgtta acaaacaagg agaaaacagt atgaaacacg
    62701 gaattaaagc actgctcatt accctgtccc tggcctgtgc cggaatgtct catagcgcgc
    62761 tggcggcagc ttctgtggcg aaaccgacgg cggtagaaac caaagcggaa gctcctgcag
    62821 cacaaagtaa agcagcagta ccggcgaaag ccagtgacga agaaggcacc cgggtcagca
    62881 ttaataatgc cagcgcggaa gagctagccc gcgcgatgaa tggcgttggc ctgaagaaag
    62941 cgcaggcgat tgtcagttat cgcgaagagt acggtccgtt taaaactgtg gaggatctaa
    63001 agcaggtgcc ggggatgggc aattcgctgg tggaacgtaa tctggcggta ttaaccctgt
    63061 aattaatttg catagtggca attttttgcc agactgaaga ggtcatacca gttatgacct
    63121 ctgtacttat aacaacaacg taaggttatt gcgctatgca aacacaaatc aaagttcgtg
    63181 gatatcatct cgacgtttac cagcacgtca acaacgcccg ctaccttgaa tttctcgaag
    63241 aagcccgctg ggatgggttg gataatagcg acagttttca gtggatgacg gcccataaca
    63301 tcgccttcgt cgtggtcaat atcaatatta actatcgtcg cccagcggta ttaagtgacc
    63361 tgttaactat taccagtcag ttgcagcaat taaacggtaa aagcggcatc ttaagccagg
    63421 tcattacact ggagccggaa gggcaggtgg tagcggatgc gcttattacg tttgtttgta
    63481 ttgatcttaa aacgcagaaa gcattagctc tggaagggga attgcgcgaa aagctggagc
    63541 agatggttaa gtaaacgttt tgtggtgccg gatgctcaag ccgcatccgg cgacacccgg
    63601 aataattacc tcaacccggt tttctgcttc atcgctgcca tcaccgtcgg tttatcggcc
    63661 agataatgat tcaaaccgtt ggcgcgtaaa ttacatgccg cacaatgacc gcaaccgtcg
    63721 cctttaaagc cgttatagca ggtcaacgtt tcgttacgga ctaaatccag tttgccgtaa
    63781 taatctgcca gcgcccaggt ttccgcttta tcaatccaca tcagcggcgt ttcaaaacga
    63841 atatctttcg ccatgcccaa actgacggca tggtttagtg ctttcacaaa ctcatcgcgg
    63901 caatccgggt agccggagaa atccgtttcg cagacgccag taattacggc ttctgctttt
    63961 acctgatacg catatattgc cgccagcgtc aggaacaaaa tattacgccc tgggacaaac
    64021 gtattcggga taccatcggc ttcaggttca taatcaggca ccggaatgct gtcacgcgtc
    64081 aggctactga ccgccagctc gttgagcagg gtgacatcca gcaccttatg cgcgcgtgcc
    64141 cccagtttca gcgccagttc gcgtgccacg tcgatttctg cgcgatgccg ctgaccgtaa
    64201 tcgaacgtca cgcaatggac ttcatcatat tgttgtaatg cctgcaccag acaggtggtg
    64261 gaatcctgac ctccactgaa cacaacgaca gcacgtttca tagataatcc tgcttgaaca
    64321 ataaaagcgt tatggtaacg cctgcgatta acccggacca gctattcatt gcgatggcgc
    64381 gggaagccag gcttcggtaa attcaaacca gccgcgcggt gtcagtcgca caccgttcac
    64441 gccgggaggg gcactaatgc gatagtgata gttgaacagc ggcgtcagcg tcgcatctgt
    64501 cattaactgg ctaaaaaccg ctttcagggc attaaatcgg ttttcttcat caggcattat
    64561 ttgcacggca tccagtgtcg attgtagatg tgcgtatgct ggagcgtcga aaacatgtgg
    64621 ccacagcgga tcgcagcgca gccattgctc cagagtatat tccggtgctt cgccaattaa
    64681 tctgtcgccc atcatgaggt ctgcgtgtgc ctgtagggtc gtgtcgtccc agttttttgc
    64741 gttatgaaaa ataattgtga gttcacagcc ttccgctgcc agtgtcgcct gtaggcgttc
    64801 tgccatggta tgaagttcta tcggtaggtg ataaaccagc gtcaaggttt tcggtagttt
    64861 gacttcatcc ggtacctgcc aatgcggaat agtccagcct ggcagtaatg catgactggc
    64921 ggtgatcagg ttttctccga cttctaacgt ttgtaataaa ccggattgat gaataatgga
    64981 gatcactttt cgcgcctgcc agagggagag tcggggactt ttgcgcaacg tcaaatagca
    65041 aaaacctaaa ctgatgccgc tactgacctg gctgacccgt tgcagctcct ccggtttgcc
    65101 gatggtgatt tgcacgggat gccgacaact ggttcccaaa tctttttcga aaagcggcgg
    65161 agttatccag tactcaaccg ctttaagcag cggatgacgt aaatggtaat aatcatggct
    65221 ttccaggcgc accagctctg ctgtgaattg tgttaagcga aaaggacccg tgccgatcag
    65281 tgggaattgc ggatgcgcca gatggctgca atagctcgcc agccggtgcg caagccagta
    65341 atcagggcga tgtaaaaaga aggtcagaca ctgcggatgg gtgacttcaa tacgcttcac
    65401 gctaataaat aattgatcca gtgctggcag ttgtaacagc atcaataatc gctggtgtaa
    65461 gtgtgaggct tttactgcat cgccgttatg ccagtgtagg gttgaacgaa gataaaagtc
    65521 ccagcgtaac ccgtcagtag aggtttccca gtgatgcgct aaatcgccaa tcgggcgctg
    65581 agtattatta tcgaagcggg tcaggccgga aaatatctgc ccggcgagat gctgctcggc
    65641 acggccgggc aaaaagcctg gttgtagcgg ttcgagcggg cgatagtagg gaatacgcaa
    65701 cgtgggtgta tcgttttgcc attgtccgcc cataaacggc tgtaacagag tgcgcagctc
    65761 acctggggcc agttgcgcca gctccagcac atcttgctgc tttccggttt ccagtgcctg
    65821 ttccatcatc gcattgcgta gcgattccgg cgtgaccaga aagcgtaatt gtccgcgctt
    65881 tccgcgtcct gactgcgcct gccactccag ccatcccgcc tcctgtgcct gacgcaacag
    65941 cgtacgaaca tggcgttcgc tgcaaaaaca gcgttcggcc agttcgctga cggtgacggt
    66001 ttgcggcttt ccggcggaag gttgccacag acgttgatac tggttaagac ggttgagcaa
    66061 tcgcatataa acccggaaca atattattta actattcact attacttccg tatatatcag
    66121 gtgatactca atcaccatta accgtgtcac agagtggaga aagaaatggc tcgtctggca
    66181 gcatttgata tggatggcac tttattgatg cctgaccatc atttaggtga gaaaaccctc
    66241 tctactttgg cgcgactgcg tgaacgcgac attaccctca cttttgccac ggggcgtcat
    66301 gcgctggaga tgcagcatat tctcggggcg ctatcgctgg atgcgtattt gattaccggc
    66361 aacggaacgc gcgtgcattc tctggaaggt gaacttttac atcgtgatga tttacctgcg
    66421 gatgtcgcgg agctggtgct gtatcagcaa tgggataccc gagccagcat gcatatcttc
    66481 aatgacgacg gttggtttac cgggaaagag atccctgcgt tgttgcaggc atttgtctat
    66541 agcggttttc gttatcagat aatcgatgtc aaaaaaatgc cactcggcag cgtcaccaag
    66601 atctgcttct gtggcgatca cgacgatctt acacgcttgc agatccagct atacgaagca
    66661 ttaggcgagc gtgcacattt gtgtttttcc gccacggatt gcctcgaagt gctgccggtg
    66721 ggctgcaata aaggcgctgc attgacggtg ctgacccaac atttaggttt atcgttgcgc
    66781 gattgcatgg cctttggtga tgcgatgaac gatcgcgaaa tgttagtcag cgtcggtagc
    66841 ggatttatta tgggcaatgc gatgccgcaa ctgcgcgcgg agctcccgca tttaccggtg
    66901 attggacatt gccgaaatca ggctgtctct cactatttga cgcactggct ggactatcca
    66961 catctacctt attcccccga ataacgagat cccttccagc accgggcaat tgcccggttt
    67021 tttttgcgtt gaatttgtca ttttgtgccg tggtgtttaa accgcacaga ataaattgtc
    67081 gtgatttcac ctttaaaata aaattaaaag agaaaaaaat tctctgtgga agggctatgt
    67141 tagataaaat tgaccgtaag ctgctggcct tactgcagca ggattgcacc ctctctttgc
    67201 aggcactggc tgaagccgtt aatctgacaa ccaccccttg ctggaagcgc ctgaaacggc
    67261 tggaggacga cggtatcctt atcggcaaag tcgccctgct ggatccggaa aaaataggcc
    67321 tcggcctgac cgcttttgtg ctgataaaaa cgcaacatca cagcagcgaa tggtattgcc
    67381 gctttgtcac ggtggttacc gaaatgccag aagtgctggg gttctggcgc atggctggtg
    67441 aatacgatta tctgatgcgc gtccaggttg ccgacatgaa acgctacgac gagttttata
    67501 agcgtctggt aaacagcgtg ccggggctgt cggacgtcac ttccagcttc gcgatggaac
    67561 agattaaata caccacttct ttacccatcg aataaatatc cagaatcagg tcaggacaca
    67621 acgcgtgcga ttatttgctc aattaagctg gtatttccgt cgggaatggc gtcgctatct
    67681 cggggctgtc gccttgcttg tcattatcgc gatgctgcaa ctggttccgc caaaagtggt
    67741 tggtattgtt gtcgatggcg tgacagaaca acactttact accgggcaga tcctgatgtg
    67801 gatcgccacc atggtgctga ttgccgttgt ggtttatctc ctgcgttacg tctggcgggt
    67861 attgctgttt ggtgcgtctt atcaactggc tgttgaactg cgtgaagatt attaccgtca
    67921 gctaagccgg cagcatcctg agttttacct gcgtcatcgc accggtgacc tcatggctcg
    67981 tgcgaccaat gacgtcgatc gcgtcgtgtt tgccgccgga gaaggggtgc tgacgctggt
    68041 ggattcactg gtgatgggct gcgctgtgtt gattatgatg tctacgcaaa ttagctggca
    68101 gttgacctta ttttccctgt tgccgatgcc agtgatggcg atcatgatta agcgcaacgg
    68161 cgatgctttg catgaacgct ttaagctggc acaggcggcg ttttccagtc ttaatgaccg
    68221 cacccaggaa agcctcacca gtatccgcat gatcaaagcc tttggtctgg aagatcgcca
    68281 gtcggcgtta tttgccgcgg atgccgaaga taccggcaaa aaaaacatgc gggtggcgcg
    68341 tattgatgct cgtttcgacc cgaccatcta tatcgcgatt ggtatggcga acttgctggc
    68401 gattggcggc ggtagttgga tggtggtgca gggcagttta acgctgggcc agctcaccag
    68461 ttttatgatg tatttaggtc tgatgatttg gccaatgctg gcgctggcat ggatgtttaa
    68521 cattgtggaa cgtggtagtg ctgcgtacag ccgtattcgc gcgatgctgg cggaagcgcc
    68581 ggtggtgaac gatggtagcg aacccgtgcc ggaagggcgt ggcgaactgg atgtaaatat
    68641 tcaccagttc acgtatccgc agactgacca tcctgcgctg gaaaacgtca atttcgccct
    68701 gaaacccggt cagatgctgg gtatctgcgg gccgactggt tccggcaaaa gtaccctgtt
    68761 gtcgctcatt cagcgtcatt tcgacgtcag cgagggggat attcgctttc atgatattcc
    68821 tctgacgaag ttacaactcg atagctggcg tagccgcctg gcggtagtta gccagacgcc
    68881 attccttttt tctgacactg tggcgaataa catcgcgctg ggttgcccga atgccaccca
    68941 gcaagagatt gagcatgtcg cgcggttagc cagcgtacat gacgatattt tgcgtctacc
    69001 gcaaggttac gatacagagg tgggcgagcg cggtgtgatg ctttccggcg ggcaaaaaca
    69061 gcgtatctcc attgctcgtg cgttattagt caacgcggaa atcctcatcc ttgatgatgc
    69121 gctttcggcg gtggacggac gcactgagca ccagatcctg cataacctgc gtcagtgggg
    69181 gcagggaaga acggtaatca tcagtgccca tcgcctttct gcactgacgg aagccagtga
    69241 aattattgtg atgcagcacg gacatatcgc ccagcgtggc aatcatgatg tgctggcaca
    69301 acaaagcggc tggtatcgcg atatgtatcg ctatcaacaa ctggaggcgg cgctcgacga
    69361 cgctccggaa aatcgcgagg aggccgtcga tgcgtagttt tagccaactg tggccgactc
    69421 tcaagcgcct gttagcgtac ggttcgccgt ggcgtaaacc gctggggatt gcggtcctga
    69481 tgatgtgggt tgcggcggcg gcagaagtca gtgggccgct gcttatcagc tattttatcg
    69541 acaatatggt agcgaaaaat aacctgccgt tgaaagtggt tgcagggctg gctgcggcgt
    69601 atgttgggct gcaactgttt gccgccgggc tacattacgc gcagtcgctg ctgtttaatc
    69661 gggcggcagt aggcgtagtg caacagttgc gtaccgacgt gatggatgct gcgttacgcc
    69721 agccattaag cgagtttgat acccaacccg tcgggcaggt gatttcccgc gtcactaatg
    69781 acactgaagt gatccgcgat ctctacgtta ccgtagtggc aactgtcctg cgcagtgccg
    69841 cgctggtggg cgcgatgctg gtggcgatgt tcagcctcga ctggcgaatg gcactggtgg
    69901 cgataatgat tttcccggtg gtgctggtgg taatggtgat ataccagcgt tacagcacgc
    69961 cgattgtccg tcgtgtgcgc gcctatctgg cggatatcaa cgacggcttt aacgaaatca
    70021 tcaatggcat gagcgttatc cagcagtttc gtcagcaggc gcgatttggc gaacgtatgg
    70081 gggaggccag tcgttcacac tatatggcga ggatgcaaac cctgcgcctc gacggttttc
    70141 tgctgcgtcc gctgctgagt ctgttttcat cgctcattct ttgtggcttg ttgatgctgt
    70201 ttggcttctc cgccagcggc accattgaag tgggcgtgct gtatgcgttt atcagctatc
    70261 ttgggcgact taacgaacca ttaatcgaac tgaccacgca acaggcgatg ctgcaacagg
    70321 ctgttgttgc tggtgagcgc gtgtttgaac tgatggacgg accgcgccag caatatggca
    70381 atgatgatcg cccgttacag agtggcacca tcgaagtcga taacgtgtca tttgcttatc
    70441 gcgatgacaa tctggtgcta aagaacatta atctctctgt gccttcgcgc aattttgtgg
    70501 cgctggtcgg gcataccggc agtggcaaaa gcaccctcgc cagtttattg atgggctatt
    70561 acccgctaac ggaaggtgag attcgccttg atggtcgtcc attaagttcg ctaagtcaca
    70621 gcgcgctgcg ccagggcgtg gcaatggtgc agcaagatcc ggtggtgctg gcggatacct
    70681 tcctcgccaa cgtgacgctg gggcgggata tctccgaaga acgcgtctgg caggcgctgg
    70741 aaaccgtgca actggcggag ctggcgcgta gcatgagcga cggtatttac acgccgctgg
    70801 gcgagcaggg gaataatctc tcagttgggc aaaagcaact gctggcactg gcgcgcgtgc
    70861 tggtcgagac gccgcaaatc ctgatccttg atgaggcaac cgccagcatt gactccggta
    70921 ctgaacaggc gattcaacat gctctggcgg cgctgcgtga acataccacg ctggtagtga
    70981 ttgctcaccg cttatcgacc attgttgatg ccgacaccat tctggtgctt catcgtgggc
    71041 aagccgtgga gcagggcact caccagcaac tgctggcggc ccagggacgc tactggcaga
    71101 tgtatcaact gcaacttgcg ggcgaagagc tggcagccag cgtgcgtgaa gaggaatcat
    71161 tgagcgcctg aatagcgcaa tatttcatcg ttggtgcaaa aatgtaacgc actgtgcact
    71221 gtcatagtgc gttttcattt tcaaacttct taacttcctg ctctctttct cgtttttcat
    71281 ttctggcaca ccgcttgcaa taccttcttc gtgtagcaga accattaccg aattctgacc
    71341 ggaggggatc tatgaagctg gtgaccgtga taatcaaacc attcaagctg gaagacgttc
    71401 gtgaagcgtt atcttccatt ggtattcagg gcctgaccgt caccgaagtg aaaggtttcg
    71461 ggcgtcagaa agggcatgcc gagctgtacc ggggggcgga atacagcgtc aatttcctgc
    71521 caaaagtaaa aattgatgtg gcgattgctg atgaccaact cgatgaagtg atcgatatcg
    71581 tcagtaaggc ggcttacacc ggaaaaattg gcgacggcaa aatcttcgtc gctgaattgc
    71641 aacgcgtcat tcgtattcgt accggcgaag ccgacgaagc ggcgctgtaa tctctggcac
    71701 acagcaacag gaacgaaaaa tgaagatagc gacgataaaa actgggcttg cttcactggc
    71761 gatgcttccg ggactggtaa tggctgcacc tgcggtggcc gataaagccg acaatgcgtt
    71821 tatgatgatt tgtactgcgc tggtgctgtt tatgactatt ccggggattg ccctgtttta
    71881 cggtgggttg attcgcggca aaaacgtgct gtcgatgctg acgcaggtga cggtgacatt
    71941 tgcactggtc tgtattctct gggtggttta cggttactcg ctggcgtttg gtgagggcaa
    72001 caacttcttc ggcaacatta actggttgat gctgaaaaac atcgaactga cggcggtgat
    72061 gggcagcatt tatcagtata tccacgtggc gtttcaggga tcgtttgcct gcattaccgt
    72121 cggcttgata gttggggcgc tggcggaacg aatccgcttc tcagctgtgt tgattttcgt
    72181 ggtggtatgg ctgacgctct cttacattcc gattgcgcat atggtgtggg gcggtggttt
    72241 gctggcttct cacggtgcgc tggatttcgc gggtggcacc gtggtgcaca ttaacgccgc
    72301 aatcgccggt ctggtgggcg cgtatctgat aggaaaacgc gtgggcttcg gtaaagaggc
    72361 gtttaaaccg cacaacctgc cgatggtctt caccgggact gccattctct atatcggttg
    72421 gtttggcttt aacgccgggt cagcgggcac ggcgaatgaa atcgcggcac tggcatttgt
    72481 gaatactgtg gtcgcaacgg cggcggcaat tcttggctgg atcttcggtg aatgggcgct
    72541 gcgtggtaag ccttcactgc tgggggcgtg ttctggcgcg attgccggtc tggtcggcgt
    72601 gacgccagcc tgcggctaca ttggggttgg cggcgcgttg attatcggcg tggtagctgg
    72661 tctggcgggc ttgtggggcg ttaccatgct caaacgcttg ctgcgggtgg atgatccctg
    72721 cgatgtcttc ggtgtgcacg gcgtttgtgg cattgtcggc tgtatcatga ccgggatttt
    72781 tgccgccagc tcgctgggcg gcgtgggctt cgctgaaggt gtgacgatgg gccatcagtt
    72841 gctggtacag ctggaaagca tcgccattac gatcgtctgg tccggtgttg tggcatttat
    72901 cggctacaaa ttggcggatc tgacggttgg tctgcgtgta ccggaagagc aggagcgaga
    72961 agggctggat gtcaacagcc acggcgagaa tgcctataac gcgtaacaag cactgcaaaa
    73021 aacagccgga cggttttcac ctccggctat ttttttaatt gtgattacgc atcacccctt
    73081 cctgaacggt cgaggcaacc agtacgccgt cttgggtata aaactcaccg cgcacaaagc
    73141 cacgtgcgct ggacgccgag gtgctctcca cgctatacag cagccattca ttcaaattaa
    73201 acgggcgatg gaaccacatg gaatggtcaa tggtggcaat ctgaatcccc ggttcgagaa
    73261 aaccgatgcc gtgcggctgt agagctaccg gcaggaagtt aagatcagaa gcgtaaccga
    73321 gcagatactg atgaacgcgc aggtcatccg gcacgctacc atttgcgcgg atccacacct
    73381 gacgatgtgg ttctgcgacg tgacctttca gtgggttatg aaactccacc ggacggactt
    73441 ccagcggacg atcgcagatg aatttatctt tcagcactgg cggcagcagg tgcgccagcg
    73501 attgggcgat ttgcgtttcc gaaggtaggc catcaggcgc tggcgcggac ggcattgttt
    73561 tttgatgttc gaaacccgct tctggtgcct ggaaagaggc agtcatataa aaaatcggtt
    73621 tgccgttttg aatagcagca acccggcggg cgctgaagct gttaccgtca cgcagcgttt
    73681 cgacatcata aataatcggc ttcttactat cgccagggcg aagaaagtag ctgtgaaacg
    73741 aatgtaccag ccgctcttca gggacggtct cttttgcagc atacaaggcc tgacccacga
    73801 cctggccgcc aaacacctgg cgtaaaccta aatcttcact ctggccgcga aagagtcctt
    73861 cctcaatttt ttccagattt aacaatgtca gtaaattttt tagcgcctga ctcatataac
    73921 tctccagtaa caaagctgcc gcagcaagcc aaagtgagtt gagtataacg caaatttgct
    73981 actggtccga tgggtgcaat ggtctgaatt acgggctaat tacaggcaga aatgcgtgat
    74041 gtgtgccaca cttgttgacg ttactatttt gttaaccact cttccggcga ggaaagttag
    74101 cccgctggtg cattgataat aaggagaaat gaatgaaact cgtgcacatg gccagtggtt
    74161 tagcggttgc gattgcgttg gcggcttgcg cagataaaag cgcggatatt cagacgccag
    74221 caccggctgc aaatacgtct atttcagcaa cacaacaacc agctatccag caaccgaatg
    74281 tctccggtac cgtctggatc cgtcagaaag tcgcactgcc gcctgatgct gtgctgaccg
    74341 tgacactttc tgacgcgtcg ttagccgatg caccgtcaaa agtgctggcg cagaaagcgg
    74401 tgcgtactga aggtaaacag tcaccattca gctttgttct gccatttaac ccggcagatg
    74461 ttcagccgaa cgcgcgtatt ctgttgagtg cggcgattac cgtgaatgac aaactggtat
    74521 ttatcaccga taccgttcag ccggtgatca accagggcgg aactaaagcc gacctgacat
    74581 tggtgccggt acagcaaacc gccgtgccgg ttcaggccag cggtggcgca acgactaccg
    74641 taccttcgac ttcaccaact caggtgaatc cgtcttcggc agttccagct cctacgcaat
    74701 attaagcgac gttaaccctc tccgcccgga gagggttagt agttccagcg ataacgctgc
    74761 aagtcgattt gcccgcttcc cgataccatc acaccttctg ccagtaatgc ctgtcgctga
    74821 cgctgtaaat ccggtccggt tagcgaaatt gtgccgtggc gattaaccac ccggtgccag
    74881 ggtaaggtgc tgccttcagg gagacgcttt aacacaccgc ccacctggcg cgcggcgcgg
    74941 ggcgatcccg ccagtttcgc cacatcaccg taagtggtga catagccttc gggaatagcg
    75001 gcgacgattt gccagacgcg ttggggaaat gaatcttctt tttccatctt ttcttcctga
    75061 ggtaattttt cagcataatc tggaaaaacg cccgagtgaa gtcgcattgc gcaagaaacc
    75121 agcatctggc acgcgatggg ttgcaattag ccggggcagc agtgataatg cgcctgcgcg
    75181 ttggttctca acgctctcaa tgggggctct gttggttctc ccgcaacgct actctgttta
    75241 ccaggtcagg tccggaagga agcagccaag gcagatgacg cgtgtgccgg gatgtagctg
    75301 gcagggcccc cacccatttc tgcctcccac cgtttcgtca aaaaatccca acatggctaa
    75361 actttaacca caactgacgt cgcaagaatt gtctggctgc gcagtacgct tcggaggtat
    75421 gtctgatgaa gtatgttgat ggttttgtgg ttgccgttcc tgccgataaa aaggatgcct
    75481 atcgggaaat ggccgctaag gctgcgccat tgtttaaaga gtttggcgcg cttcgtattg
    75541 tcgaatgctg ggccagcgat gtaccggatg gcaaagtgac cgattttcgt atggcggtga
    75601 aagcggaaga gaatgaagag gttgtcttta gctggattga atacccttca aaagaggtcc
    75661 gcgacgctgc taatcaaaag atgatgtcgg acccacggat gaaagagttc ggcgagtcca
    75721 tgccgtttga cggcaagcga atgatctatg gcggattcga gtcaatcatc gacgaatagg
    75781 tagcgtgacg ggctgtgcgg cgtgccgtca gcccaaaaat tcacaaatgt tgctcggccc
    75841 agcgtaagaa atcttctttc ggtaatgcct tgctgtagag ccagccctga ccgtagtgca
    75901 cgccatgctg gcgtaaccac tcttcttgtt tactggtttc gattccctcc gctaccattt
    75961 tcagtttcag tgtttttgcc atttcgatga tatgcggcgt gacattttta tattccagcg
    76021 catcaacgaa agatttatcg atcttcagaa tgtcgacatc cagatcctgt aaataactta
    76081 aacttgaata ccccgtacca aaatcatcaa gataaatttc atggcccgcc tcccggtagc
    76141 gagaaattat cggggcgctg gttttcggat cggcaaactc gcgttcagtg agttcaagcg
    76201 cgatctgtct gggattaacc tgatagtgat tgatcatgtc acgcagcaat tgcgggattt
    76261 tttccgaggt gagcacgggg gattcaagat tgatcgaaat atgctgctgt ggatgctgac
    76321 gcagccagtc gcccatatct tcaaagacgc ttcttataat cagtagcgtc aatggctcag
    76381 aaaggcccgt ttgctgtgcc agcggaataa aactatctgg tgacaaccaa ctaccgtctg
    76441 tctgcggcca gcgcgccagt gcctcagcac cgacaatttt gccattggct aaggagacaa
    76501 tcggctgata gtgcacgcaa atatcacgat tttcgatagc atcctgcagc cgatgatgcg
    76561 gtgactgaat acggcgcaaa atacgcagca caaacatcgc tgccagcagg ccaatcacca
    76621 acccgagcgg taaccaaata aagacttgcc gatgccagcc tttctgcaac attttcgttg
    76681 aagcccatgt gatgatcgaa atattcatct ccggtaaggg caggatatcg taaatgattc
    76741 cattattttc gatatgctca ccgggtgttt tttgtagcct ggtaataatt ccctgagcaa
    76801 tttcatcgct gctggttatg acaacgttat gggcattgcc aataatggcg gcatcaattt
    76861 gccatgagct atagggaatg acatcaataa aggaagcggg gtcgatcatg acgacataat
    76921 gtgccgttcc catggcgacc atgtaacgga taatgcctaa atcgttatgc gatgttaacc
    76981 agacacgata accatctttc gaaattttac ctggctcggg gaaggtatcg ggcggacttt
    77041 catgctccag agacgaacac tggggaacgt tgttatcgat ataagccact tcctgaatat
    77101 agcgataact gtaagatacc cgacgcattt ccatgagatg ggcttcgcta caggcagcgc
    77161 cttgccatct ttccagctcc tgcagcgcat ctttcccttg tgtcgccacc ttattggctc
    77221 gaatagcgac gcgggaggaa taggtatcca gctcttcaat aaacgatgtt tctacctgct
    77281 gatgggccag ccagatgctt aagccgacag gcagcaatac tgaaagaatc agtactcccg
    77341 aaataaggcc gaccagatgt cgtgttctca ccagcatatc cttattaaca cagtgtaggg
    77401 aaagtatatc tgattgtgga aaaaggctgg ctggagataa ggaggtagag ctggtatttc
    77461 atgaagtgat gggtggaaac gatcattgtc atttgaccag gcgcagagct ttacgcctgg
    77521 tatgtaaccc taacttaaga tgttgattcg gcgcgagcga gggtaaaaat atcgtaaaaa
    77581 gacagttcac ctttacggac gatcattttt tgcagttgtt ccttatgaac atccgcgaca
    77641 cgcggagagt tcaagatggc ttcaaccagc gcggcaggta caaagcgcgt gttgtaccat
    77701 tcgccgttat agcaaacgcg gaaatccagc acgtcgatat cttcatagcg gtagcgtggg
    77761 tagacatcga aaaagaagaa accattaagc aggataaata atacaaccag tagccagaca
    77821 gagcctgaca gcgtttcgga ctgcaacatc accgccaggg tggcaaaaaa agcaacgtac
    77881 ataccgataa acagccccgg atgtttacgg ataaaactga tactaaagcg gggtttgttg
    77941 tcgcgttttt cgcgggtatt cagagactca atcgtttcgg tcagcaggcg ttgtatttcg
    78001 gtcatcgttt gccttcgtgg tatctgcaac tttccaggga acaccctatt ttaacgtggg
    78061 aatagtagag gggaagtaac agatctacca caattttgca taacagttgc gaaaaaccga
    78121 ttacaatttt ttaattattc tggctggatt accgcccacg acaacgttgt ccgggacatc
    78181 ttttgtgaca actgcacctg aggctaccac gacgttatca ccaatggtca caccagggtt
    78241 aatgaccgcg cgtccgccaa tccagacgtt attaccgatg gtgacgggtt tccccagttc
    78301 agcaccgcta ttacgtgcta cagggtcgat gggatgtgtt gccgtgtaga tatgaacgcc
    78361 tggtgccaac atacagttat caccgatgcg aatagggcag acatcaagca tcacgcaatc
    78421 gaagttggcg aaaaaattat taccgagaaa aatgttatag ccatagtcac agcgaaacgt
    78481 tggctcaata taagcctctg tcacctgacc gaatagatca gcgagaattt gctggcgtaa
    78541 tgtgtgctct tccgccaggg aatgattgta tcggtgaata agctgacgag cgcgcaggcg
    78601 atcgcgagat aacgtctcat ctgccgagcg atacaactca ccagcaatca tcttttcttt
    78661 ttctgtgctc attactgacc tccggttgct gaaaatgcgg caacacagta agacgaaaag
    78721 tcagtgaaga gaacgttccc attacatctg tgtgataaag atcacatagg gtatgtcttc
    78781 atggcgaaaa agtataaaat tcttaataaa cagccggtta tagctccgaa agcgaattat
    78841 ttattagcga ataaatttcc atactgagga agggatcttg tcgtacagtt tattcatggt
    78901 caattcggcg aggcggtgat ctgcggctga gtaaaatacc gccagttcat tatctgataa
    78961 ttcgtattta tttttctcga taacacgctc cagcgtgtca attgtctggc aacgacgtaa
    79021 acgcattaaa taatcggttt tcgttaaagg tttttcggac atacttctac ctatggttgt
    79081 aataattcta acaagataaa ctcgcaggat tctctttcgt cgcattgaca aaacaacgga
    79141 atagtcgatt acctgacttc cgccatttct gaagatcctg catattaata ccataactac
    79201 tgaacaacat aaaggtgtca tccagatatt cgtcgatctg ctcaatgagc ttattgtctt
    79261 cattatactt aattttgtaa ttaagtgcga aggtcgcaat atgctcaatc agttcattca
    79321 actggaggtt gatctccgag gttgggtcgt ttacccagcc atgattgctt tcttcaaggt
    79381 ttgcaaggca gtcatgatac agggtttcac agagaaactt aagctgtgcg atatcatgtc
    79441 ttttgggtga gtattcatcc ataacgcgtc cccttcttag cggttgaact aacggacacc
    79501 tttcgggatg gaaaaaactt actgacctgg acttgccctc tcgtttgtta gcttaactat
    79561 aagccactct ttgcaggttt tcatcgcatt attacgaaaa attacaatta ggaaggaagc
    79621 gggacaggac tcactttttc atactagcac taacccgcag caggtaaaag cagtttgctc
    79681 gaactattca taacatttca ggattatcgc cagatgaaat tggtgacact aataccagga
    79741 ttgctctg
//
LOCUS       DAPHKZ010000006        73493 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.006, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000006 DAPHKZ010000000
VERSION     DAPHKZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 73493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73493
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.006"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            40..624
                     /locus_tag="RH288_000384"
     CDS             40..624
                     /locus_tag="RH288_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4029484.1"
                     /translation="MNKVTKTAIAGLLALFAGNAAATDGEIVFDGEILKSACEINDSD
                     KKIEVALGHYNAEQFRNIGERSPKIPFTIPLVNCPMTGWEHDNGNVEASFRLWLETRD
                     NGTVPNFPNLAKVGSFAGIAATGVGIRIDDAESGNIMPLNAMGNDNTVYQIPAESNGI
                     VNVDLIAYYVSTVVPSEITPGEADAIVNVTLDYR"
     gene            704..1399
                     /locus_tag="RH288_000385"
     CDS             704..1399
                     /locus_tag="RH288_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV4029485.1"
                     /translation="MSKRTFAVILTLLCSFCIGQALAGGIVLQRTRVIYDASRKEAAL
                     PVANKGAETPYLLQSWVDNIDGKSRAPFIITPPLFRLEAGDDSSLRIIKTADNLPENK
                     ESLFYINVRAIPAKKKSDDVNANELTLVFKTRIKMFYRPAHLKGRVNDAWKSLEFKRS
                     DHSLNIYNPTEYYVVFAGLAVDKTDLTSKIEYIAPGEHKQLPLPASGGKNVKWAAIND
                     YGGSSGTETRPLQ"
     gene            1428..3944
                     /locus_tag="RH288_000386"
     CDS             1428..3944
                     /locus_tag="RH288_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV4029486.1"
                     /translation="MPQRHHQGHKRTPKQLALIIKRCLPMVLTGSGMLCTTANAEEYY
                     FDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQKKITFTANAEQLL
                     QPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDFNHQQLNLSIPQ
                     IALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNMQNGANFGPW
                     RLRNYSTWTRNDQTSSWNTISSYLQRDIKALKSQLLLGESATSGSIFSSYTFTGVQLA
                     SDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVSAGAFEINDLYPSSNSG
                     DLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDSKEPEFAEAT
                     AIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDNQHSFHGY
                     QWCTQYIKDIPETNTNIAVSYYRYTNDGYFSFNEANTRNWDYNSRQKSEIQFNISQTI
                     FDGVSLYASGSQQDYWGNNDKNRNISVGVSGQQWGVGYSLNYQYSRYTDQNNDRALSL
                     NLSIPLERWLPRSRVSYQMTSQKDRPTQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHN
                     SSLNASYRSPYGTFSAGYSYGNDSSQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDAN
                     GASGVRIQNYPGIATDPFGYAVVPYLTTYQENRLSVDTTQLPDNVDLEQTTQFVVPNR
                     GAMVAARFNANIGYRVLVTVSDRNGKPLPFGALASNDDTGQQSIVDEGGILYLSGISS
                     KSQSWTVRWGNQADQQCQFAFSTPDSEPTTSVLQGTAQCH"
     gene            3955..5046
                     /locus_tag="RH288_000387"
     CDS             3955..5046
                     /locus_tag="RH288_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4029487.1"
                     /translation="MKRAPLITGLLLISTSCAYASSGGCGADSTSGATNYSSVVDDVT
                     VNQTDNVTGREFTSATLSSTNWQYACSCSAGKAVKLVYMVSPVLTTTGHQTGYYKLND
                     SLDIKTTLQANDIPGLTTDQVVSVNTRFTQIKNNTVYSAATQTGVCQGDTSRYGPVNI
                     GANTTFTLYVTKPFLGSMTIPKTDIAVIKGAWVDGMGSPSTGDFHDLVKLSIQGNLTA
                     PQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTSKIKNSLQMR
                     IDGTTGVVDQYNLVARRRSSDNVPDVGIRIENLGGGVANIPFQNGILPVDPSGHGTVN
                     MRAWPVNLVGGELETGKFQGTATITVIVR"
     gene            complement(5089..5949)
                     /gene="rsmI"
                     /locus_tag="RH288_000388"
     CDS             complement(5089..5949)
                     /gene="rsmI"
                     /locus_tag="RH288_000388"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDV4029488.1"
                     /translation="MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGALVGELLAWVK
                     EDENRRKGEMVLIVEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALEQQG"
     gene            6014..8050
                     /gene="lpoA"
                     /locus_tag="RH288_000389"
     CDS             6014..8050
                     /gene="lpoA"
                     /locus_tag="RH288_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoA"
                     /protein_id="HDV4029489.1"
                     /translation="MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQ
                     ADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDAQRREKT
                     LLAVEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
                     QEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDP
                     DMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQ
                     PVPVSAPATSTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNV
                     EELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIP
                     RSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITLRATT
                     DSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATL
                     YASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMG
                     VDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRNLSWLQYQQGQVVPVS"
     gene            8008..8403
                     /locus_tag="RH288_000390"
     CDS             8008..8403
                     /locus_tag="RH288_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDV4029490.1"
                     /translation="MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVN
                     ERGGEIDLIMREGRTTIFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGS
                     FDTVDCRFDVVAFTGNEVEWIKDAFNDHS"
     gene            8423..9013
                     /gene="diaA"
                     /locus_tag="RH288_000391"
     CDS             8423..9013
                     /gene="diaA"
                     /locus_tag="RH288_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HDV4029491.1"
                     /translation="MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD"
     gene            9023..9598
                     /gene="yraP"
                     /locus_tag="RH288_000392"
     CDS             9023..9598
                     /gene="yraP"
                     /locus_tag="RH288_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HDV4029492.1"
                     /translation="MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVD
                     GANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
                     LVTEREAKAAADIASRVSGVKRVTTAFTFIK"
     gene            complement(9712..10752)
                     /locus_tag="RH288_000393"
     CDS             complement(9712..10752)
                     /locus_tag="RH288_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDV4029493.1"
                     /translation="MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWEPYYGKAFTA
                     AETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLR
                     TLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPAT
                     LVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFS
                     RWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVVAMAVAGCLFVI
                     PTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAV
                     SGVIVGGLALLF"
     gene            complement(10825..11460)
                     /locus_tag="RH288_000394"
     CDS             complement(10825..11460)
                     /locus_tag="RH288_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDV4029494.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGV
                     FNPHDPQLSDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
                     TLFAPLFRLLPGNWKSIDARDVARVMLAESMRPEHEGVTILSSSELRKRAE"
     gene            11588..12106
                     /gene="yhbO"
                     /locus_tag="RH288_000395"
     CDS             11588..12106
                     /gene="yhbO"
                     /locus_tag="RH288_000395"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HDV4029495.1"
                     /translation="MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVK
                     GKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(12086..12529)
                     /locus_tag="RH288_000396"
     CDS             complement(12086..12529)
                     /locus_tag="RH288_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HDV4029496.1"
                     /translation="METLIAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFY
                     ILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYN
                     RRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRDSGTEQA"
     gene            12580..12882
                     /gene="yhbQ"
                     /locus_tag="RH288_000397"
     CDS             12580..12882
                     /gene="yhbQ"
                     /locus_tag="RH288_000397"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage response exodeoxyribonuclease YhbQ"
                     /protein_id="HDV4029497.1"
                     /translation="MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKG
                     ELTLVFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAELLSSLQTPEIKSD"
     gene            complement(12869..13372)
                     /locus_tag="RH288_000398"
     CDS             complement(12869..13372)
                     /locus_tag="RH288_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV4029498.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEY
                     HEHFNRF"
     gene            complement(13366..13890)
                     /locus_tag="RH288_000399"
     CDS             complement(13366..13890)
                     /locus_tag="RH288_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HDV4029499.1"
                     /translation="MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
                     TAPETKQTSVGEPC"
     gene            14099..15094
                     /locus_tag="RH288_000400"
     CDS             14099..15094
                     /locus_tag="RH288_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDV4029500.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMSEGRCYLSSYLTGESPNTIGACSPARFVRWQQTPQGLESRLNEVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKADPQNFVPQSAWMETLGSMSEGTQTTLGAYHRKWQ"
     gene            15103..15981
                     /locus_tag="RH288_000401"
     CDS             15103..15981
                     /locus_tag="RH288_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417628.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDV4029501.1"
                     /translation="MKYSLGPVLWYWPKETLEEFYQQAATSSADVIYLGEAVCSKRRA
                     TKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNM
                     CAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
                     QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLN
                     GIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANS
                     DCNGYWRRLAGLELQA"
     gene            16062..17069
                     /locus_tag="RH288_000402"
     CDS             16062..17069
                     /locus_tag="RH288_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="luciferase-like monooxygenase"
                     /protein_id="HDV4029502.1"
                     /translation="MTDKTIAFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELL
                     G"
     gene            complement(17187..18431)
                     /gene="mtr"
                     /locus_tag="RH288_000403"
     CDS             complement(17187..18431)
                     /gene="mtr"
                     /locus_tag="RH288_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HDV4029503.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAVGRLKTALLTFAPPV
                     VGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMIALIL
                     VFGVGNALVHILSSFNLLPVYQ"
     gene            complement(18585..20474)
                     /gene="deaD"
                     /locus_tag="RH288_000404"
     CDS             complement(18585..20474)
                     /gene="deaD"
                     /locus_tag="RH288_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HDV4029504.1"
                     /translation="MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGR
                     DVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPH
                     TGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRR
                     FGGDA"
     gene            complement(20467..20547)
                     /gene="yrbN"
                     /locus_tag="RH288_000405"
     CDS             complement(20467..20547)
                     /gene="yrbN"
                     /locus_tag="RH288_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HDV4029505.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(20654..21538)
                     /gene="nlpI"
                     /locus_tag="RH288_000406"
     CDS             complement(20654..21538)
                     /gene="nlpI"
                     /locus_tag="RH288_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HDV4029506.1"
                     /translation="MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(21647..23782)
                     /gene="pnp"
                     /locus_tag="RH288_000407"
     CDS             complement(21647..23782)
                     /gene="pnp"
                     /locus_tag="RH288_000407"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDV4029507.1"
                     /translation="MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAQLLSEDQMLGAVVFGHEQQQVVIQN
                     INELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSE
                     TIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRV
                     YTGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRIRLSIKEATEQSQPAAAPEAPAAEQGE"
     gene            complement(24029..24298)
                     /gene="rpsO"
                     /locus_tag="RH288_000408"
     CDS             complement(24029..24298)
                     /gene="rpsO"
                     /locus_tag="RH288_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDV4029508.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR"
     gene            complement(24447..25391)
                     /gene="truB"
                     /locus_tag="RH288_000409"
     CDS             complement(24447..25391)
                     /gene="truB"
                     /locus_tag="RH288_000409"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDV4029509.1"
                     /translation="MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVT
                     FSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEH
                     LRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAP
                     LEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(25391..25792)
                     /gene="rbfA"
                     /locus_tag="RH288_000410"
     CDS             complement(25391..25792)
                     /gene="rbfA"
                     /locus_tag="RH288_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDV4029510.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMS
                     RDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTSVVKHDEERRVNPDDSKED"
     gene            complement(25956..28628)
                     /gene="infB"
                     /locus_tag="RH288_000411"
     CDS             complement(25956..28628)
                     /gene="infB"
                     /locus_tag="RH288_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDV4029511.1"
                     /translation="MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQT
                     LIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERL
                     AAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
                     QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDN
                     AEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADRE
                     EARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIK
                     AMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAP
                     VVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAA
                     FTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPD
                     RVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMAS
                     GAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSI
                     PVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMT
                     EGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASN
                     AILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLA
                     EVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVR
                     NGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA"
     gene            complement(28653..30140)
                     /gene="nusA"
                     /locus_tag="RH288_000412"
     CDS             complement(28653..30140)
                     /gene="nusA"
                     /locus_tag="RH288_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDV4029512.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
                     VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGE
                     EVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLW
                     DDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGW
                     ELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKEL
                     LEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAA
                     RGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA"
     gene            complement(30168..30620)
                     /gene="rimP"
                     /locus_tag="RH288_000413"
     CDS             complement(30168..30620)
                     /gene="rimP"
                     /locus_tag="RH288_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDV4029513.1"
                     /translation="MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLV
                     LRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(30827..30903)
                     /locus_tag="RH288_000414"
     tRNA            complement(30827..30903)
                     /locus_tag="RH288_000414"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30867..30869),aa:Met,seq:cat)
     gene            31251..32594
                     /gene="argG"
                     /locus_tag="RH288_000415"
     CDS             31251..32594
                     /gene="argG"
                     /locus_tag="RH288_000415"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDV4029514.1"
                     /translation="MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQG
                     RWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKG
                     DSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ"
     gene            complement(32602..34227)
                     /locus_tag="RH288_000416"
     CDS             complement(32602..34227)
                     /locus_tag="RH288_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417641.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDV4029515.1"
                     /translation="MTVFNKFARTFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFF
                     VLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDP
                     DEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQ
                     FAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVR
                     DTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
                     LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETV
                     YVRGFDELLLPHLSQALQQNTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDAC
                     YDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHV
                     PMFIWYSPVLGDGVDRTTENNIFSTAYNNYLINAWMGVTKPEQPQTLEEVIAHYKGDS
                     RVVDANHDVFDYVMLRKEFTEDKQGNPTPEGQG"
     gene            complement(34686..34772)
                     /locus_tag="RH288_000417"
     tRNA            complement(34686..34772)
                     /locus_tag="RH288_000417"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34736..34738),aa:Leu,seq:gag)
     gene            complement(34787..35119)
                     /gene="secG"
                     /locus_tag="RH288_000418"
     CDS             complement(34787..35119)
                     /gene="secG"
                     /locus_tag="RH288_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDV4029516.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     KPTSDIPN"
     gene            complement(35347..36684)
                     /gene="glmM"
                     /locus_tag="RH288_000419"
     CDS             complement(35347..36684)
                     /gene="glmM"
                     /locus_tag="RH288_000419"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDV4029517.1"
                     /translation="MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
                     FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVG
                     ATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVK
                     AVTAEVEAALGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV"
     gene            complement(36677..37525)
                     /gene="folP"
                     /locus_tag="RH288_000420"
     CDS             complement(36677..37525)
                     /gene="folP"
                     /locus_tag="RH288_000420"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312083.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDV4029518.1"
                     /translation="MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
     gene            complement(37615..39549)
                     /gene="ftsH"
                     /locus_tag="RH288_000421"
     CDS             complement(37615..39549)
                     /gene="ftsH"
                     /locus_tag="RH288_000421"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDV4029519.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNND
                     QVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(39649..40278)
                     /gene="rlmE"
                     /locus_tag="RH288_000422"
     CDS             complement(39649..40278)
                     /gene="rlmE"
                     /locus_tag="RH288_000422"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HDV4029520.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP"
     gene            40404..40697
                     /gene="yhbY"
                     /locus_tag="RH288_000423"
     CDS             40404..40697
                     /gene="yhbY"
                     /locus_tag="RH288_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDV4029521.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHH
                     ELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(40853..41329)
                     /gene="greA"
                     /locus_tag="RH288_000424"
     CDS             complement(40853..41329)
                     /gene="greA"
                     /locus_tag="RH288_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDV4029522.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL"
     gene            41577..43010
                     /gene="dacB"
                     /locus_tag="RH288_000425"
     CDS             41577..43010
                     /gene="dacB"
                     /locus_tag="RH288_000425"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HDV4029523.1"
                     /translation="MRFSRFIIGLTSCIAFSVQAANVDEYITQLPAGANLALMVQKVG
                     ASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLV
                     ARFGADPTLKRQDIRNMVATLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCF
                     SAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCE
                     LDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGITWSGTLLR
                     QTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSD
                     AVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     EPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(43196..44368)
                     /gene="cgtA"
                     /locus_tag="RH288_000426"
     CDS             complement(43196..44368)
                     /gene="cgtA"
                     /locus_tag="RH288_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HDV4029524.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLATK
                     PRWLVFNKIDLLDKVEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIE
                     NPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR"
     gene            complement(44384..45349)
                     /locus_tag="RH288_000427"
     CDS             complement(44384..45349)
                     /locus_tag="RH288_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV4029525.1"
                     /translation="MKQQAGIGILLALTTAICWGALPIAMKQVLEVMEPPTIVFYRFL
                     MASIGLGAILAVKKRLPPLRVFRKPRWLILLAVATAGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRSTQVVGALMLLSGLVMFFNTSLVEIFTKLTDYTWG
                     VIFGVGAATVWVSYGVAQKVLLRRLASPQILFLLYTLCTIALFPLAKPGVIAQLSHWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLFFSDLLSLAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHTTVVSQPRAGE"
     gene            complement(45476..45733)
                     /gene="rpmA"
                     /locus_tag="RH288_000428"
     CDS             complement(45476..45733)
                     /gene="rpmA"
                     /locus_tag="RH288_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDV4029526.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTK
                     FHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE"
     gene            complement(45754..46065)
                     /gene="rplU"
                     /locus_tag="RH288_000429"
     CDS             complement(45754..46065)
                     /gene="rplU"
                     /locus_tag="RH288_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDV4029527.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            46324..47295
                     /gene="ispB"
                     /locus_tag="RH288_000430"
     CDS             46324..47295
                     /gene="ispB"
                     /locus_tag="RH288_000430"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HDV4029528.1"
                     /translation="MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGG
                     KRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNA
                     DGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMN
                     ACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR"
     gene            47523..47801
                     /gene="sfsB"
                     /locus_tag="RH288_000431"
     CDS             47523..47801
                     /gene="sfsB"
                     /locus_tag="RH288_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HDV4029529.1"
                     /translation="MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSR
                     PWPKGEMIIAKALGTDPWVIWPSRYHDPQTHEFIDRTQLMRSYTKPKK"
     gene            complement(47849..49108)
                     /gene="murA"
                     /locus_tag="RH288_000432"
     CDS             complement(47849..49108)
                     /gene="murA"
                     /locus_tag="RH288_000432"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDV4029530.1"
                     /translation="MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(49163..49417)
                     /gene="ibaG"
                     /locus_tag="RH288_000433"
     CDS             complement(49163..49417)
                     /gene="ibaG"
                     /locus_tag="RH288_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HDV4029531.1"
                     /translation="MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(49577..49870)
                     /gene="mlaB"
                     /locus_tag="RH288_000434"
     CDS             complement(49577..49870)
                     /gene="mlaB"
                     /locus_tag="RH288_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HDV4029532.1"
                     /translation="MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDL
                     SRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR"
     gene            complement(49870..50505)
                     /gene="mlaC"
                     /locus_tag="RH288_000435"
     CDS             complement(49870..50505)
                     /gene="mlaC"
                     /locus_tag="RH288_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HDV4029533.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKN
                     EQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQREAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
                     WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK"
     gene            complement(50524..51075)
                     /gene="mlaD"
                     /locus_tag="RH288_000436"
     CDS             complement(50524..51075)
                     /gene="mlaD"
                     /locus_tag="RH288_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HDV4029534.1"
                     /translation="MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYA
                     TFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
                     NSGDAPAAAPGNNETTEPVGTTK"
     gene            complement(51080..51862)
                     /gene="mlaE"
                     /locus_tag="RH288_000437"
     CDS             complement(51080..51862)
                     /gene="mlaE"
                     /locus_tag="RH288_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HDV4029535.1"
                     /translation="MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
                     IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISL
                     FNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN"
     gene            complement(51870..52679)
                     /gene="mlaF"
                     /locus_tag="RH288_000438"
     CDS             complement(51870..52679)
                     /gene="mlaF"
                     /locus_tag="RH288_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HDV4029536.1"
                     /translation="MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIL
                     ADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS"
     gene            52889..53866
                     /locus_tag="RH288_000439"
     CDS             52889..53866
                     /locus_tag="RH288_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDV4029537.1"
                     /translation="MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEVIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLR
                     RELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
                     EQLAELPRDGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAI
                     GTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDY
                     SVMLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPILVE"
     gene            53880..54866
                     /gene="kdsD"
                     /locus_tag="RH288_000440"
     CDS             53880..54866
                     /gene="kdsD"
                     /locus_tag="RH288_000440"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HDV4029538.1"
                     /translation="MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEK
                     MFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPH
                     VKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADV
                     MTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV"
     gene            54887..55453
                     /gene="kdsC"
                     /locus_tag="RH288_000441"
     CDS             54887..55453
                     /gene="kdsC"
                     /locus_tag="RH288_000441"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HDV4029539.1"
                     /translation="MSKAGASLATCYGPVSADVIAKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKAKLVEDRCATLGITHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            55450..56025
                     /gene="lptC"
                     /locus_tag="RH288_000442"
     CDS             55450..56025
                     /gene="lptC"
                     /locus_tag="RH288_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HDV4029540.1"
                     /translation="MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKS
                     EHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAK
                     LTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            55994..56551
                     /gene="lptA"
                     /locus_tag="RH288_000443"
     CDS             55994..56551
                     /gene="lptA"
                     /locus_tag="RH288_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HDV4029541.1"
                     /translation="MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQS
                     LDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNG
                     KPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
                     TTVLVPSQLQDKNNKGQTPAQKKGN"
     gene            56558..57283
                     /gene="lptB"
                     /locus_tag="RH288_000444"
     CDS             56558..57283
                     /gene="lptB"
                     /locus_tag="RH288_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HDV4029542.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAV
                     LQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            57331..58764
                     /gene="rpoN"
                     /locus_tag="RH288_000445"
     CDS             57331..58764
                     /gene="rpoN"
                     /locus_tag="RH288_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDV4029543.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESN
                     PLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSG
                     DYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDETGYLTVPLED
                     ILESIGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARL
                     IISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            58787..59074
                     /gene="hpf"
                     /locus_tag="RH288_000446"
     CDS             58787..59074
                     /gene="hpf"
                     /locus_tag="RH288_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HDV4029544.1"
                     /translation="MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVE
                     KVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQH"
     gene            59192..59683
                     /gene="ptsN"
                     /locus_tag="RH288_000447"
     CDS             59192..59683
                     /gene="ptsN"
                     /locus_tag="RH288_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HDV4029545.1"
                     /translation="MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLS
                     LPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTEGTP
                     DEA"
     gene            59729..60583
                     /gene="rapZ"
                     /locus_tag="RH288_000448"
     CDS             59729..60583
                     /gene="rapZ"
                     /locus_tag="RH288_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDV4029546.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKP"
     gene            60580..60852
                     /gene="npr"
                     /locus_tag="RH288_000449"
     CDS             60580..60852
                     /gene="npr"
                     /locus_tag="RH288_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HDV4029547.1"
                     /translation="MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVIALFNSGFDED"
     gene            61066..61698
                     /gene="yrbL"
                     /locus_tag="RH288_000450"
     CDS             61066..61698
                     /gene="yrbL"
                     /locus_tag="RH288_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HDV4029548.1"
                     /translation="MIRLSEQSPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIR
                     RELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVYDVIADFDGKPSITLTEFAEQCR
                     YEEDIAQLRQLLKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
                     PLATWSKWCCLRKQERLWKRFIAQPALAIALQKDLQPRESKTLALTSREA"
     gene            complement(61695..62423)
                     /gene="mtgA"
                     /locus_tag="RH288_000451"
     CDS             complement(61695..62423)
                     /gene="mtgA"
                     /locus_tag="RH288_000451"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HDV4029549.1"
                     /translation="MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAV
                     MVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKA
                     LAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRS
                     RQAWILRQMYQLGGEPFMQQHQLD"
     gene            complement(62420..63073)
                     /gene="elbB"
                     /locus_tag="RH288_000452"
     CDS             complement(62420..63073)
                     /gene="elbB"
                     /locus_tag="RH288_000452"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HDV4029550.1"
                     /translation="MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQ
                     QVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLS
                     NFASLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE"
     gene            complement(63303..65639)
                     /gene="arcB"
                     /locus_tag="RH288_000453"
     CDS             complement(63303..65639)
                     /gene="arcB"
                     /locus_tag="RH288_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HDV4029551.1"
                     /translation="MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     SLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSV
                     AEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFK
                     PGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDD
                     VLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLI
                     TDGLAVFEKMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK"
     gene            complement(65735..66664)
                     /locus_tag="RH288_000454"
     CDS             complement(65735..66664)
                     /locus_tag="RH288_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312117.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDV4029552.1"
                     /translation="MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
                     HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHI
                     VKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE"
     gene            67339..71799
                     /gene="gltB"
                     /locus_tag="RH288_000455"
     CDS             67339..71799
                     /gene="gltB"
                     /locus_tag="RH288_000455"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HDV4029553.1"
                     /translation="MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIV
                     EEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPTDLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNET
                     GSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELD
                     DDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLP
                     VPAPMAVGAIQTRLVDQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VGLCFQGAVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARE
                     TRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHPGKALYCTEN
                     NPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     ADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
                     EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCIL
                     GKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLSVDALAIHEEHLRGLITEHVQ
                     HTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            71812..73230
                     /gene="gltD"
                     /locus_tag="RH288_000456"
     CDS             71812..73230
                     /gene="gltD"
                     /locus_tag="RH288_000456"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HDV4029554.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
                     CADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGE
                     TRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPA
                     DAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNWLEV"
BASE COUNT        18127 a        19823 c        18188 g        17355 t
ORIGIN      
        1 aaatatgatt atgtacttgt tacaaggata aggttatata tgaataaagt tacaaaaaca
       61 gctattgcgg gcttacttgc gcttttcgca ggtaatgccg ctgcaaccga tggtgaaata
      121 gtttttgatg gcgagatttt aaaatccgct tgtgaaatca atgactctga taagaaaatt
      181 gaagttgctc ttggtcacta taatgccgaa cagtttcgta atattggcga gcgtagccca
      241 aaaattccat tcactattcc tttagttaac tgcccaatga ctgggtggga gcacgataac
      301 ggcaacgttg aagcgtcttt ccgtctatgg ctggaaacgc gagataatgg caccgtccct
      361 aacttcccta atctggcaaa agtaggctct tttgctggca tagcggcaac aggtgtgggt
      421 atccgtattg acgatgcgga aagcggaaac attatgccac tgaatgctat gggcaatgat
      481 aacacggttt atcagatccc ggcggaatcc aatggtattg tcaatgttga cctcatcgct
      541 tactacgtat caaccgtagt tccatcagaa atcaccccag gggaagcaga cgctatcgtt
      601 aacgtaacgc tggattaccg ttaatacgtt agggcgttat ctgacctgtc agataacgcc
      661 cttttccttc ctctttctcg ttgtatcagg ttgaaaaata actatgtcaa aacgaacatt
      721 cgcggtgata ttaaccttgt tgtgtagctt ctgtattggc caggcgcttg caggaggaat
      781 cgttttacag cgaacgcgag tgatctatga tgccagccgc aaagaggctg cgttacctgt
      841 cgcaaacaaa ggcgcagaaa cgccttattt actgcaatca tgggtagata atatagatgg
      901 taaaagccgt gccccattta ttataacccc accgctattt cgtcttgagg ctggcgatga
      961 ctcatcactg cgaattatta aaacagctga taacctgcct gaaaataaag agtcgctgtt
     1021 ctacattaat gttcgtgcca ttccagcaaa gaaaaaatca gatgatgtta atgctaacga
     1081 gttgacgctg gtatttaaaa cacggatcaa aatgttttat cgccccgcac acctgaaggg
     1141 acgggtaaac gatgcgtgga aatcactgga atttaaacgt agtgaccatt cactcaatat
     1201 atataaccca actgaatatt acgtcgtatt tgccggactg gcagtcgata aaaccgatct
     1261 cacaagcaaa attgaatata tcgcgcccgg agaacataaa cagttaccac ttcctgcatc
     1321 tggcggaaag aacgtgaaat gggctgcgat caatgattat ggcggcagtt ccgggacaga
     1381 aactcgtcca ctgcaataaa aaatataaaa acacaggtca tcagggaatg ccacaacgac
     1441 accaccaggg acataaacgc acaccgaaac agttggcgct catcatcaaa cgttgtttgc
     1501 cgatggtgct cactggcagc ggcatgcttt gcactaccgc taacgccgaa gagtattatt
     1561 tcgaccccat tatgctggaa accacaaaaa gtggtatgca aacaaccgat ctgtcgcgtt
     1621 tttcaaaaaa atatgcacaa ctaccaggaa cttatcaggt tgatatctgg ctgaataaaa
     1681 agaaggtttc acagaaaaaa attacattta ccgccaatgc agagcaactt ctgcagccac
     1741 agtttacggt agaacaacta cgtgagctgg gtattaaggt ggatgaaatc ccggcgctgg
     1801 ctgaaaaaga tgacgatagc gtgatcaact cgcttgaaca aatcattccc ggtacagctg
     1861 ctgaatttga tttcaatcat cagcaactta atttgagcat tccccaaatt gcactgtacc
     1921 gtgatgcaag aggttacgtc tccccttctc gttgggacga tggtatacca acgctgttta
     1981 ccaactactc gtttacaggt tctgataacc gttaccgcca gggcaatcgt agccaacgac
     2041 agtacctgaa tatgcaaaat ggtgctaatt ttggcccctg gcgattacgc aactattcca
     2101 catggacacg caacgatcag acatcaagct ggaataccat cagtagttat ttacaacgtg
     2161 atatcaaggc gttgaagtct cagttgcttc tgggagaaag cgccaccagc ggcagtattt
     2221 tttccagcta cacctttact ggcgtgcaac tcgcttccga cgataatatg ttgccaaaca
     2281 gccagcgcgg atttgcccca acggtacgcg gtatcgcaaa cagtagtgca atcgtgacta
     2341 tcaggcaaaa tggttatgtg atctatcaaa gcaacgtgtc agcgggtgcc tttgaaatta
     2401 acgatctcta cccctcttcc aacagcggcg atttagaagt cacgattgaa gaaagtgacg
     2461 gtacacaacg tcgctttatc cagccttatt cttcattacc catgatgcag cgacctgggc
     2521 atctaaagta tagcgcgacc gctggacgct atcgcgctga tgcaaacagt gatagcaagg
     2581 aacccgaatt tgctgaagcc acggcaatat atggtttgaa taatactttt acgctgtatg
     2641 gcggcctgct cggttctgaa gattattatg cgctggggat cggtatcggc ggcacacttg
     2701 gcgcactggg cgcgttgtcg atggatatca acagagctga cacccaattc gataaccagc
     2761 actcttttca tggctatcaa tggtgtacgc agtacatcaa agatatcccg gaaaccaaca
     2821 ccaatatcgc tgtcagctac tatcgctata ccaacgatgg ctattttagt tttaatgaag
     2881 ccaatacccg caattgggac tataacagtc gccaaaaaag tgaaattcaa ttcaacatca
     2941 gccagacaat atttgatggg gtaagtctgt atgcctccgg ttcgcagcaa gactattggg
     3001 gcaataacga taaaaacagg aatatctctg ttggggtttc cggccagcaa tggggagttg
     3061 gttacagcct gaattatcaa tacagccgct acactgatca aaataatgac cgcgcactct
     3121 ctttgaatct cagtattccg ttagaacgct ggttaccgcg tagccgggtt tcctatcaga
     3181 tgaccagcca gaaagatcgc ccaacccaac atgaaatgcg tcttgatggc tcactgctgg
     3241 atgatggtcg cctgagctat agcctggaac aaagtctgga tgacgataac aaccataaca
     3301 gtagcctgaa cgccagttac cgttcacctt atggcacctt cagtgccgga tacagctacg
     3361 gtaatgacag cagccaatac aattacggcg ttaccggcgg cgtggttatc catcctcatg
     3421 gcgtgacgct ctcgcaatat ctgggcaacg cttttgcgct tatcgatgct aacggagcat
     3481 ctggcgtgag gatacaaaac tatccgggga ttgctaccga tccttttggc tatgcagtgg
     3541 ttccttatct cacaacttat caggaaaacc gtctctcggt agatactacg cagctgcccg
     3601 ataacgtcga tcttgaacaa acaacacagt ttgtggtgcc caacagaggt gcaatggtag
     3661 cggcgcgttt caacgccaat atcggttatc gcgtacttgt tacagtcagc gatcgcaacg
     3721 gtaaaccgtt gccctttggc gctcttgcca gcaacgatga tacggggcaa caaagtatcg
     3781 tcgatgaggg cggcatacta tatctctctg ggatatcgag taaatcacaa agctggactg
     3841 tacgctgggg aaatcaggca gatcaacaat gtcagtttgc tttcagtaca ccggattcag
     3901 aacctacaac ctctgtatta caaggcacag cgcagtgcca ttaaggataa aaaaatgaaa
     3961 agagcgcctc ttataacagg tcttttgttg atatccacat cctgcgctta tgcctcctca
     4021 ggagggtgtg gagccgacag cactagcggt gcgacaaatt acagcagtgt ggttgatgat
     4081 gttacggtga accagacaga taacgtgaca ggacgggagt ttacctctgc aacgctaagt
     4141 agcactaact ggcaatacgc ctgttcctgc tctgcgggta aggcagttaa acttgtctat
     4201 atggtcagcc ccgtacttac caccactgga catcagacag gatattacaa actcaatgac
     4261 agcctggata ttaaaaccac attacaggca aacgacattc caggactcac aaccgaccag
     4321 gttgtctctg ttaacacccg attcacacag ataaaaaaca acacggtata ttctgctgca
     4381 acccaaacgg gtgtttgcca gggtgatacg tctcgttatg gacccgttaa tattggtgcg
     4441 aacaccacct ttaccctgta tgtcaccaag ccatttctcg gctcgatgac cattccgaaa
     4501 acggatattg ccgtcattaa aggcgcgtgg gtcgatggaa tgggaagccc gtctacaggt
     4561 gacttccatg atttagtcaa gttatcgatt cagggaaatc tcaccgcccc acagtcgtgc
     4621 aaaattaatc agggcgatgt tattaaggtt aattttggat tcatcaatgg tcagaagttt
     4681 accacccgca atgccatgcc agacggtttt actccagtag actttgatat cacttatgac
     4741 tgtggtgata cttcaaagat taaaaactcg ttgcaaatgc gcatcgacgg tacaactggg
     4801 gtagtagacc agtacaacct ggtcgccagg cgaagaagtt cagacaatgt gcccgatgtc
     4861 ggtattcgta ttgaaaatct cggcggcgga gttgcaaata ttccttttca gaacggtatc
     4921 cttcccgttg atccttccgg gcatggcacc gtcaatatgc gcgcctggcc agttaatctg
     4981 gtcggtggtg agctggaaac aggaaaattt cagggcacag ccaccattac cgtcatcgtg
     5041 cggtaaaaga agacgttgcg ttttgattaa cgcaacgctt cggcactgtt acccctgctg
     5101 ctccagcgca tacttataca gcgcattttt cttcacgccg tgaatttctg cggccagcgc
     5161 cgccgctttt ttcagcggca gttctgcctg tagcagcgcc agcgtgcgca gggcatcggc
     5221 gggtaagtct tcttcctgtg ctttatgacc ttcgacaatc agcaccattt cgcctttgcg
     5281 acggttttca tcttccttta cccacgccag cagctcgcca acgagcgcgc cgtgaatggt
     5341 ttcccaggtt ttggtcagct cacgcgccag aaccacgtag cgggattcgc ctaataccgc
     5401 aacgatatct tccaggctat ctaacagacg gtgggtagat tcataaaaaa tcagcgtgcg
     5461 cggctccgct tcaatggctt ttagcgcatc acggcggcct tttgatttgg caggtaaaaa
     5521 gccttcgtaa cagaaacggt cagagggtaa acccgctgcg cttaacgcag tgatagcagc
     5581 acacggcccg ggtagcggca ccacgcggat ccccgcttca cggcaggtac gcaccagatg
     5641 gtagccagga tcgttaatta gcggcgttcc ggcatcggaa accagcgcaa tgttttgccc
     5701 ctcttgcagc ttcgccagca gcgtttcagc tttttgttgt tcgttatggt cgtgcagcgc
     5761 aaacaaccgg gcattaatcc caaaatgttg cagcaataaa ccggtgtgac gagtatcctc
     5821 ggcggcaatc agatcaacgg cctgtaatac ctctaacgca cgctgggtga tatccgccag
     5881 attgccgatt ggcgtcggta caatgtaaag ctggccctga gaattatccg ccgattggtg
     5941 ttgtttcatt gtgtcgtccg tattgccgat ttaatattga gcattgcgta aaaaaaatat
     6001 cactggatac attatggtac cctcaacatt ttctcgtttg aaagccgcgc gttgtctgcc
     6061 tgttgttctg gcagccctga ttttcgccgg ttgtggcacc catactcccg atcagtccac
     6121 tgcttatatg cagggcacgg cgcaggctga ttctgccttt tatcttcagc agatgcagca
     6181 aagctctgat gataccagga tcaactggca attactcgcc attcgtgcac tggtgaaaga
     6241 aggtaaaacc gggcaggcgg ttgagttgtt taaccaacta ccgcaagaac tgaacgatgc
     6301 tcagcgtcgc gagaaaacac tgctggcggt agagattaaa ctggcgcaga aagattttgc
     6361 tggcgcgcaa aacttgctgg cgaaaatcac acctgccgat ttagaacaaa accagcaagc
     6421 gcgttactgg caggcaaaaa tcgatgccag ccaggggcgt ccttccattg atttactgcg
     6481 cgcgttaatt gctcaggaac cgctgcttgg cgcgaaagaa aaacagcaga atattgatgc
     6541 cacctggcag gcgctctcct ccatgactca ggaacaggcg aatacgctgg tgatcaacgc
     6601 cgacgaaaat attctgcaag gctggctgga tctgcagcgc gtctggtttg ataaccgtaa
     6661 cgatcccgac atgatgaaag ccgggatcgc cgactggcag aaacgttatc cgaacaatcc
     6721 gggcgcgaaa atgctgccaa cgcagttggt taacgtaaaa gcgtttaaac cagcctcgac
     6781 caacaaaatc gccctgctgt tgccactgaa tggccaggca gcggtatttg gtcgcactat
     6841 tcagcaaggc tttgaagcgg cgaaaaatat cggcactcag ccagtggcag ctcaggtagc
     6901 tgccgcacct gccgcagacg tagctgaaca acctcagccg caaaccgtgg atggcgttgc
     6961 cagcccggca caagcctcgg ttagcgatct gaccggtgaa cagcctgcag cccagccggt
     7021 gcctgtaagc gccccggcga caagcaccgc agcggtaagc gcacccgcaa atccatccgc
     7081 agagctgaaa atctacgata cctcatcaca accacttagc cagatcttaa gccaggttca
     7141 gcaggatggc gcgagtattg tggtcggtcc gttgctgaaa aataacgttg aagagttgct
     7201 gaagagcaac actccgctga acgtactggc actgaaccag ccggagaata tcgaaaatcg
     7261 cgtcaatatt tgttacttcg cgctttcacc ggaagacgaa gcgcgcgatg cagcgcgtca
     7321 tattcgtgac cagggtaaac aagcgccgct ggtgctgatc ccacgcagtt cattgggcga
     7381 tcgcgtagcc aatgcgtttg cgcaagagtg gcagaaactg ggcggcggca ccgttctgca
     7441 acaaaaattt ggttccacca gcgaattacg cgcgggtgtt aacggcggtt ctggtattgc
     7501 tttaacgggt agcccgatta ctctcagagc gacaaccgac tccggcatga cgaccaacaa
     7561 tccaacgctg caaaccacgc caaccgatga ccagttcacc aataatggcg gtcgtgtcga
     7621 tgcggtgtac attgtggcaa cgccgggtga aatcgctttt atcaaaccga tgatcgccat
     7681 gcgtaacggt agccagagcg gtgcaacgct gtacgccagc tcccgcagtg cgcaagggac
     7741 cgctggcccg gatttccgac tggagatgga aggcttgcag tacagcgaaa tcccgatgct
     7801 ggcaggcggt aatctaccgt taatgcagca ggcactcagc gcggtgaata acgattattc
     7861 actggctcgc atgtatgcga tgggcgtcga tgcctggtcg ctggcaaatc atttctcaca
     7921 aatgcgccag gttcagggtt ttgaaatcaa cggtaatacc ggaagcctga cggctaaccc
     7981 ggattgcgtg attaacagga acttatcatg gctacagtac caacaaggtc aggtagtccc
     8041 cgtcagttaa ccaccaaaca gaccggcgat gcgtgggaag cacaagcgcg tcgctggctg
     8101 gaaggcaaag gactgcggtt tatcgccgct aacgtgaacg agcgtggcgg cgagatcgat
     8161 ctgataatgc gtgaaggccg gaccaccatt tttgtcgagg tacgctatcg ccgctctgcg
     8221 ctttatggcg gcgcggcagc cagtgtgacc cgcagcaaac aacacaaatt attacagact
     8281 gcccgcttgt ggctcgcgcg tcataatggg agttttgata ctgtggattg ccggttcgat
     8341 gtggtagcct tcaccgggaa tgaggttgag tggattaagg atgcctttaa tgaccactca
     8401 taattaaggt ttaaggatta gcgtgcaaga aagaattaaa gcttgcttca ctgaaagcat
     8461 tcaaactcaa attgcggcgg cagaggcgct tccggatgcc atctcccgtg cagccatgac
     8521 gctggttcag tctctgctca atggcaacaa aatcctctgt tgtggtaatg gaacttccgc
     8581 tgccaatgca cagcattttg ctgccagcat gatcaaccgt ttcgaaacgg agcggcccag
     8641 cttacctgcc attgcactaa atactgataa tgttgtctta acggcgattg ccaacgatcg
     8701 cttacatgat gaagtgtatg caaaacaggt gcgggcgctg ggtcatgcgg gagatgtatt
     8761 gttagccatt tccacccgtg gcaacagccg cgatattgtt aaagcagttg aagccgccgt
     8821 tacgcgtgat atgaccattg tggcattgac cggctatgac ggcggcgaac ttgcaggttt
     8881 gttagggcca caggatgtgg agatccgcat tccttcgcat cgtagtgctc gcattcagga
     8941 aatgcatatg ctgacggtaa attgcctgtg cgatctgatc gataacacgc ttttccctca
     9001 ccaggatgat taaggagaat acatgaaggc attatcgcca atcgcagtcc ttatttccgc
     9061 gctgctgttg caaggttgtg ttgccgctgc cgtagtgggt accgctgctg tgggtaccaa
     9121 agccgcaact gacccacgca gtgtcggcac ccaggtggac gatggtaccc tggaagtgcg
     9181 cgtgaacagc gcattgtcga aagacgaaca gattaagaaa gaagcgcgca ttaatgtaac
     9241 ggcctatcag ggcaaagtgc tgctggttgg gcagtcacca aatgctgaac tttcggctcg
     9301 cgccaaacag attgctatgg gcgtagacgg tgccaacgaa gtgtataacg agattcgtca
     9361 gggccagccg attggtctgg gcgaagcatc taacgatacg tggatcacca ccaaagtgcg
     9421 ttcgcagctc ttaaccagcg acctggtgaa atcgtccaac gtgaaagtga ccaccgaaaa
     9481 cggtgaagtg ttcctgatgg ggctggtgac tgaacgtgaa gcgaaagcgg cggcagatat
     9541 tgccagccgg gtgagcggcg tgaagcgggt aactacggcg tttacgttta ttaaatagca
     9601 gccccttgta atgcctgatg cgacgcttgc cgcgtcttat caggcctaca acgatacaaa
     9661 ccgtaggtca gataaggcgt ttacgccgca tccgacatgt tttccctcaa atcagaacaa
     9721 cagcgccagc ccgccgacaa tcacaccaga cactgccacc atcgcccctg tcagccataa
     9781 ggctttcgcc gggaacgctt tgcgcagcat aatcagtgac ggcaaactca ctgccgggag
     9841 cgtcatcaac aatgccagcg ccggagcggt tcccatacct gccagcatca tcgtttgtac
     9901 aatcggaatt tctgctgccg tgggaatgac aaacaagcat cctgctaccg ccatcgccac
     9961 cacccacatc aggctgttat cgacagcacc atcggcatgg gggaataacc agacgcgagc
    10021 ggcacccaac accagtactg caaggatgta aaccgggatc gtactccaga aaagcgtcca
    10081 tagcgccctg ccccagcggc taaaaaaccc gccctgtgct tccggtatgt caatttcgac
    10141 cggtgcctgc gtttgcggtg tttcacgcac ccatttttgc accagcgtcg caatcagcaa
    10201 caccatcacc agcccggcca ccagacgaat cgccgcaaaa ccccagccga ggacaaagcc
    10261 cataaacacc agcgtcgccg ggtttaacac cggattgccc atccagaatg ccagcgcacc
    10321 gcccatcgac acctgttggc gacgcattcc cgccgcgacc ggagccgcac agcaggtaca
    10381 catcatgccc ggcaacgaaa acagcgttcc cagcagcgtg ccgcgaaagc gcgattgccc
    10441 aagcgtacgc aacaaccagt cacgcgggat cagcacctga atcaacgaac cgaggatcac
    10501 ccccagcacc gccgctttcc ataccgcgag gaaatagatc atcgcgtaat ccaacgccgc
    10561 ctgccatggg ttagcatccg cctgcgcaag gatagattta ccgatactgt gggtttcggc
    10621 agcagtaaac gctttgccgt agtaaggttc ccatttcaca taccagagac cggcaatgac
    10681 aacgagaaag aaaagcgcgg gtttccacca ctgaatgggc gttgccgcct gagatgaaga
    10741 ctgaccagtc atagcattcc ccaggaataa gttatgataa ttgagcgcgt gaatattacg
    10801 ctcactatca attcttggga ataattattc agctcttttg cgtaattctg aagagcttaa
    10861 aatcgtcacg ccttcatgct caggccgcat cgactctgcc agcatgaccc gcgccacgtc
    10921 tctcgcatca atggatttcc agttacctgg taacaaacgg aacagcggcg caaaaagcgt
    10981 ttcgttcatc cgctgtttgc tacgatcgcc cagtaacatc gacgggcgag caatggtcaa
    11041 tttcggccag ttctgggcga ttaatgcttc ttccatctcc cctttgacgc ggttatagaa
    11101 aaacggcgag tgggcattgg cacccatcgc actgactacc aacatatgct gcgcgcccag
    11161 tcgccgcccg gttaatgcgg tatccactac cagcgtgtaa tcggcatgaa taaacgcctc
    11221 tttgctcccc gcttctcgcc gcgtggtgcc gagacaacaa aacacaatgt cgatgggatc
    11281 ggtgacctgc gccaacgcgt cactcagttg cggatcatgg ggattaaaca ccccgggcat
    11341 atcgcccaac ggacgtcgcg tcggcgcagc aatggcgtta actttcggtt cgttaatcaa
    11401 catccgcagc aggtgaccgc ccaccagccc cgttgcgcct gtaatcagta cctgactcat
    11461 cttcgctcct ttacagaatt gtctgccttg cgctccacgg ctcatgcacc aggcttaata
    11521 gaccatgagg taattatccc cgattgtggg aaattcgcct catccaatgc aacaacgcgg
    11581 aggaagcatg agtaagaaaa ttgccgtttt aatcactgat gaatttgagg attcagaatt
    11641 tacttcaccc gcagacgagt tccgtaaagc cggacacgaa gtgattacca ttgaaaaaca
    11701 agcgggtaaa acggtgaaag gcaaaaaagg agaagccagc gtgaccatcg ataaatccat
    11761 cgatgaagtg acgcctgcgg agtttgatgc cctgctgcta ccgggcggcc attcaccgga
    11821 ttatctgcgt ggggacaacc gttttgtcac ctttacccgt gattttgtga atagtggcaa
    11881 accggtgttt gccatctgtc acggcccgca gttgctgatc agcgccgatg tgattcgggg
    11941 gcgcaaactg accgcagtta aaccgatcat tattgatgtt aaaaatgcgg gcgcggaatt
    12001 ttacgatcag gaagtcgtgg ttgataaaga tcagctggtt accagccgga caccggacga
    12061 tctgccagcg tttaaccgcg aggcgttacg cctgctcggt gcctgagtcg cgtagccaaa
    12121 tcattttttt accaaagccc agcgtgttgt cggtgaattt gatttcatcg agccggattt
    12181 cccacaccgg ggccgacagc attctggcaa ccggaaagcg acgattgtac gccttgcgcg
    12241 cgaggtcgct ttcctcacct tccagcctgc ggatctcacc tttaaactgc acaccgcgaa
    12301 ttaacgctac cgttttcggc tgaccgttta ccgttccggc aaccgcagcc tgcggcccac
    12361 tcatctgcgc gtggcgcgtt ttttcttccg tcaaaatgta gaaggcgact ttctgcgcat
    12421 caaaaagata aaaggcatta gcgcaccaga gttccccttc ctgctgcaca caccaagtga
    12481 caacatgttg ttttgccagc caacggctga tggcgatgag tgtttccatt gctgttctct
    12541 tttatactgt gggcctgacc ttaacatgcg acgcagacga tgacaccctg gtttctttac
    12601 ttgatccgta ccgccgacaa taagctttat accgggatca ccacggatgt cgaacgccgc
    12661 tatcagcagc accaaagcgg caaaggggcg aaagcactgc gcgggaaagg agaactaacg
    12721 ctggtgtttt ccgcgccagt gggcgatcgt tcgctggcgt tacgggcgga atatcgcgtt
    12781 aagcaactga ccaaacggca aaaagagcgt ctggtagcgg aaggcgcagg gtttgcagag
    12841 ctgttaagca gtctgcaaac cccggagatt aaaagcgatt gaaatgctcg tgatactcaa
    12901 ccaggccggt aacgccattc agcgcgtcat ccgctaaacg atgtacctgg aaggcgcttt
    12961 cagtgcccgg ccagcggcaa cgcagatcgt gatgcgccgc cagttcaaag ccgaaacgac
    13021 tgtacagcgc cggatcgccc agcgtcacca ctgcggcata gccgaactca ttaagcgaat
    13081 cgagtccttc atagaccagt tggcgtgcca gcccctgtcc acggtatttt tcatcaaccg
    13141 ccaacggtgc catgccgacc cattgcaggt cttcgccctg cacatcaacc ggactaaatg
    13201 ccacatagcc aatgacctga ccttcgtcat ctgtcgccac cagccccagc gtcagaaagc
    13261 catcttcacg cagatcgtga accagcttcg cttccgcatc actttcgaat gagcgacgca
    13321 gcagggcatc aatacccggc gcatcaatgg gaatttctac tcgaattagc atggttcacc
    13381 taccgatgtc tgtttggttt caggcgcggt tttcattccc gcctcaacaa aatccgccag
    13441 ttgcagcagc atcatgcgta aggctttcgg catttgctcc agttcaatgg cgtccatcag
    13501 gtttttcaca tacagcccca gctccgtatc gccttcaatc accagccgac gctggaagaa
    13561 gagcgtatcc ggatcttgtt tacgcgccgc aatcatcagc agatcgctgg cgtcggcact
    13621 aaaactcaca tcagcttgcg cgttctggct aacgaccagt ttgccattca ccaccgaggt
    13681 aaaccattgc aggtcaatat cacgcacatg aatacttaac cagcggcctt caagaaactc
    13741 cagctcgcca tcatccagcg cctggcggaa ttgccagctt aagacctgct caagaacctg
    13801 gcgttttagc gcaaatggcg tcagttttac cggtacactc aacagagatg gccccaaatg
    13861 cacaatacgg gaacgcagtt tatccaacac gagttttact ccctgtttca acaatcatcc
    13921 tattttgcca tatcagaaaa ataacatagc ggtataaatc aacaattcca tatgaaattg
    13981 ctgctaccac caatacaact ttaactgcct taaatcaaaa attgtcgcag caaggttaac
    14041 taaaatccca gttcgttaac atttttgcgt tttgatagcg caaccttcag gaaaaattat
    14101 ggagctgctc tgccctgccg gaaatctccc ggcgcttaag gcggccatcg aaaacggcgc
    14161 agatgctgtt tatatcgggc taaaagatga taccaatgcc cgtcacttcg ccggccttaa
    14221 ctttaccgag aaaaaattgc aggaagcggt gagttttgtc catcaacatc gccgcaaact
    14281 tcacatcgcg attaacactt ttgcgcatcc ggacggttac gcccgttggc agcgcgccgt
    14341 ggatatggcg gcgcagctgg gtgccgacgc gctgatcctc gccgacctcg ccatgctgga
    14401 gtacgccgcc gagcgttatc cgcatattga gcgccacgta tcggtgcagg cttcggcgac
    14461 caatgaagag gcgattaact tttatcatcg ccattttgac gttgctcgcg tggtgctgcc
    14521 gcgcgtgttg tcgattcatc aggtgaaaca actggcacgg gtcacacctg taccactgga
    14581 agtctttgct ttcggcagcc tgtgcattat gtcggaaggt cgttgctatc tgtcgtcgta
    14641 tctgacgggt gagtcgccca acaccatagg cgcgtgttct ccggcccgtt tcgtgcgctg
    14701 gcaacaaacg ccgcaggggc tggaatcccg cctgaacgaa gtgctgatcg accgttatca
    14761 ggacggcgaa aacgcaggtt atccgacgct atgtaaaggg cgttatctgg tggacggcga
    14821 gcgctatcac gcgctggaag aaccaaccag tctcaatacc ctggaactgc tgccggagtt
    14881 aatggcggcg aatattgctt cggtgaaaat tgaaggccgc cagcgtagcc cggcgtatgt
    14941 cagccaggtg gcgaaagtct ggcgtcaggc tatcgaccgt tgtaaggccg atccgcaaaa
    15001 ctttgtaccg caaagcgcgt ggatggagac gctcgggtcg atgtccgaag gcacgcaaac
    15061 cactcttggc gcatatcacc gtaaatggca gtgagaaaag caatgaaata ttccttaggg
    15121 ccagtgctgt ggtactggcc aaaagagacg ctggaagaat tttatcagca ggccgccacc
    15181 agcagcgccg acgtgattta tcttggtgaa gcggtatgca gcaagcgtcg ggcaaccaaa
    15241 gttggcgact ggctggagat ggcaaaatcg ctcgccggga gtggtaagca gattgtgctc
    15301 tccacgctgg cgctggtgca ggcatcatct gaactgggcg aactgaaacg ctatgttgag
    15361 aacggtgagt ttctgattga agccagcgat ctcggcgtgg tgaatatgtg cgctgaacgc
    15421 aaactgccgt tcgtcgccgg gcacgcgctg aactgctaca acgcggtgac actgaaaata
    15481 ttgctcaaac agggcatgat gcgctggtgt atgccagtgg agctttcccg cgactggctg
    15541 gtgaatctgc ttaatcagtg cgatgagctg ggcattcgta accagtttga agtggaagtc
    15601 ctgagctacg gtcatctgcc gctggcctac tccgcccgct gctttaccgc gcgttcggaa
    15661 gaccgcccga aagatgagtg tgaaacctgc tgcattaagt atccgaacgg gcgcaacgtg
    15721 ctgtcgcagg aaaaccaaca agtgtttgta ctcaatggca ttcagaccat gagcggctac
    15781 gtttacaacc tcggtaacga gctggcatcc atgcagggcc tggttgatgt ggtccgcctg
    15841 tcaccgcagg gtactgacac tttcgcgatg ctcgacgcct tccgcgctaa tgaaaatggc
    15901 gctgcaccac tgccgttgac ggcgaacagc gactgtaacg gctactggcg gcggctggca
    15961 ggactggagc tgcaagccta agtaaatagc tcactttgtt aacaacttta actactcttt
    16021 aatgcagtat taaagattaa tcggtaacaa agtgagctgt tatgactgat aaaaccattg
    16081 cgttttcgct actcgatctg gcccccattc ccgaaggttc ttcagcgcga gaagcattct
    16141 cccactctct cgatctcgcc cgtctggctg aaaagcgcgg ctatcatcgc tactggctgg
    16201 cagaacacca caatatgact ggcattgcca gtgctgccac gtcggtattg atcggctatc
    16261 tggcggcgaa taccaccacg ctgcatctgg ggtctggcgg cgtgatgttg cctaaccact
    16321 caccgttggt cattgcagaa cagttcggca cgcttaatac actctatccg gggcgaatcg
    16381 atttggggct gggtcgtgct ccgggtagtg accaacggac aatgatggcg ctacgtcgtc
    16441 atatgagcgg cgatattgat aatttccccc gcgatgtggc ggagctggtg gactggtttg
    16501 acgcccgcga tcccaatccg catgtgcgcc cggtaccagg ctatggcgag aaaatccccg
    16561 tgtggttgtt aggctccagc ctttacagcg cgcaactggc ggcgcagctt ggtctgccgt
    16621 ttgcgtttgc ctcacacttc gcgccggata tgctgttcca ggcgctgcat ctttatcgca
    16681 gcaacttcaa accgtcagca cggctggaaa aaccatacgc gatggtgtgc atcaatatta
    16741 tcgccgccga cagcaaccgc gacgctgaat ttctgtttac ctcaatgcag caagcctttg
    16801 tgaagctgcg ccgtggcgaa accgggcaac tgccgccgcc gattcaaaat atggatcagt
    16861 tctggtcacc gtctgagcag tatggcgtgc agcaggcgct gagtatgtcg ttggtaggtg
    16921 ataaagcgaa agtgcgtcat ggcttgcagt cgatcctgcg cgaaaccgac gccgatgaga
    16981 ttatggtcaa cgggcagatt ttcgaccacc aggcgcggct gcattcgttt gagctggcga
    17041 tggatgttaa ggaagagttg ttgggatagt gtgtcttaac gcgggaagcc ttatccgagc
    17101 tggcaacgct gtcctacata gacctgataa gcgaagcgca tcaggcattg tgtaggcagc
    17161 agaaatgtcg gataaggcac cgctgattac tgatacaccg gcagtaaatt aaagctcgat
    17221 aaaatatgca ccagtgcgtt gccgacgcca aacaccagaa tcagcgcaat catcggcttg
    17281 ccaccccaga cgcggaattt cgggctgcca aagcgtttac gcgatgcacg ggctaacagc
    17341 gccggaacaa ttgccgccca gatggtagcc gctaaaccag cataaccaat ggcgtacagg
    17401 aatccgttcg ggaacaacag cccccccaca actggcgggg caaaggtcag caatgccgtt
    17461 ttcaagcggc ccacagccga gtcgtcgaaa ccaaacagat ctgccagata gtcaaacaaa
    17521 cccagcgtta cgccgaggaa cgaactcgct accgcaaagt ttgagaacac gaccagcagc
    17581 agatccagac tacggctgtt cagtacgccg cttaacgcct gtaccagcac atcaatatta
    17641 ccgcccttct ctgcaatacc gataaactcc ggacgcggga tgttacccat cgtcgccagc
    17701 aaccagatgg tatacagcgc cagcgccatc agcgtaccgt acaccagaca tttcacgatg
    17761 gttttcggat ctttgccgta atacttcatc aggcttggca cgttaccgtg ataaccaaac
    17821 gatgccagac agaacggcag ggtcatcaac agatacggtg cataagacgc attgctttcg
    17881 gcgacgttga acaatgtcgc aggctgcaca tgccccagca ggctaccaaa ggtgaggaag
    17941 aaggtaatga ctttcgcccc cagcacaatc gctgtcatgc gactgacggc tttagtgctc
    18001 aaccacacca caaacgctac cagcaatgca aaaccaaaac ccgccgcccg tgccgggacg
    18061 tttagtgaca tctctgcgaa ggtgtgatgc agaatcgaac cactggcaga aatataggca
    18121 taggtcagga tatagagcac aaaggcaatg gaaatgccgt tgaccacgtt ccagcctttg
    18181 cccagcaaat ctttggtgat ggtgtcaaaa ctcgaaccga ttctgtaatt caggttagct
    18241 tccagaatca tcaagccgga atgcagcata cagaaccagg taaagatcag cgccgccatt
    18301 gaccagaaaa accacgcccc ggacatgacc actggcagag aaaacatccc tgcgccaata
    18361 atggtgccgc cgataatcac cacgccgcca agcagcgacg gtgacgtttg ggtggtggtt
    18421 agtgttgcca tgagggcttc tctccagtga aaaatagtgc gactgcgttg ttatgcattg
    18481 cactgtacca gtacacgagt acaaaagaca gaaaaaaagc cccgatggta aaaatcgggg
    18541 ctgtatatat tattttacag attgtgttcg ctgttcagcg atgattacgc atcaccaccg
    18601 aaacgacgac gaccggtaga atcatcacga cgcggagcgc ggccttcacg acgttcgccg
    18661 ctaaaacgac gaccatcacc acggccacct tcacggcgtt caccgctgaa gttacgaccg
    18721 ccttcacgac gttcgccacc gaaaccacga ccaccgccac gacgctcacc gccagtatgc
    18781 ggctgtgcat cgcccagtaa ctgcatgttc atcggcttgt tgagaatgcg agtgcgcgta
    18841 aagtgttgca gcacttcacc cggcatacct ttcggcagtt cgatggtgga gtgagaagca
    18901 aacagcttga tgttaccaat gtaacggctg ctgatgtcgc cttcgttagc aatcgcacca
    18961 acgatatgac gaacttcaac accatcatcg cggcccactt caatgcggta cagctgcata
    19021 tcgccaacat cacgacgttc acgacgcgga cgatcttcac ggtcaccacg cgggccacgg
    19081 tcgttacgat cgcgcggacc acggtcatca cggtcacgga attcacgttt cggacgcatc
    19141 ggcgcatctg gcggtacgat cagagtacgt tcaccctgtg ccattttcag cagtgccgca
    19201 gccagagttt cgagatccag ctcttcacct tcagcagtcg gctgaatttt gctcagcagt
    19261 gcgcggtatt gatccagatc gctgctttcc agctgctgct gtactttagc ggcgaatttt
    19321 tccagacggc gtttgcctag cagttctgcg ttcggcagtt ctacttccgg aatagtcagc
    19381 ttcatagtac gttcaatgtt gcgcagcaga cgacgctcgc ggttctcaac gaacagcagc
    19441 gcgcggccag cacgacccgc acgaccggta cgaccgatac ggtgaacgta agactcagaa
    19501 tccatcggga tatcgtagtt aactaccagg ctgatacgct caacgtccag gccacgggct
    19561 gcaacgtcgg tcgcaatcag gatgtccaga cgaccatctt tcaggcgttc cagtgtctgt
    19621 tcacgcagcg cctggttcat gtcaccgttc agcgcggcgc tgttgtagcc gttacgctca
    19681 agagcttcag ccacttccag agtcgcgttt ttggtacgaa cgaagataat cgccgcatca
    19741 aaatcttccg cttccaggaa acgtaccagt gcttcgtttt tgcgcatacc ccagacagtc
    19801 cagtagctct ggctgatgtc aggacgggta gtcacgctgg actgaatgcg cacttcctgc
    19861 ggctctttca taaagcggcg ggtaatgcga cgaatcgctt ccggcatggt tgcagagaac
    19921 agagcggtct gatgaccttc cgggatctgc gccataatgg tttcaacgtc ttcgatgaag
    19981 cccatgcgca gcatttcgtc agcttcatcc agaaccagac cgctcagttt agagaggtcc
    20041 agagtgccac gtttcaggtg gtccagcaga cggcccggag taccgacaac gatctgcggc
    20101 ccctgacgca gggcgcgtaa ttgcacgtca taacgctggc cgccgtacag agcaaccaca
    20161 tttacgccgc gcatgtgttt agagaaatcc gtcattgctt cagcaacctg taccgccagt
    20221 tcgcgggtcg gtgccagcac cagaatctgt ggtgctttca gctcaggatc aagattctgc
    20281 aacagaggta aagagaatgc tgcagttttt ccgctccccg tctgggccat acccagaacg
    20341 tcgcggccat tcagcagatg tggaatacac tctgcctgaa ttggagatgg tttttcgtaa
    20401 cccagatcgt taagggcttc aaggatagga gccttcaggc ccagatctgc aaaagtggtt
    20461 tcgaattcag ccatgtagta cgtgtgcctc aaaattaatg gcggccagtc tacataactc
    20521 atcatgaaat tgatcagcaa ttttcattga aaagtgtgaa ccggctcaaa gtaggtgtat
    20581 taacgaacaa caacgccctc acccgttaag gtgatggcaa tcaaaaaaga ttacgggctg
    20641 atgtgtacgt cagctattgc tggtccgatt ctgccaggtc atcttggtcc tggcccagga
    20701 gcgataattc caacaatgcg tatcggtgct caacaaagtt atgaacgttg ttggcaaccg
    20761 ccagtttgaa cagtgccgtg gcgctgtcca aatcccccag acttaggtag tacttaccta
    20821 aatagaagtt ggtttcactg agatgctcag cgagcgaggt gttatccgtt gcgtccgcct
    20881 tgagcctttc cattaacgtt tgttcgctaa tgttgcccag gtagaactcg acaatgttcc
    20941 atccccactg ttccttatcc gatttttcga agtgctgttt caacacttct ttagcctgct
    21001 tctcatcgag cttctgctcg gcgagataaa gccacagact acggaaagga tcattgggat
    21061 cgtcttgata aaacgccagc agatcatctt gcgctaactt gtcacgaccg ccgtaatata
    21121 atgcgatccc gcgattcaag tgcgcgtagt tgtaagttgg atcaagctca agtacagaat
    21181 caaacgcttc ataggcagca tcaaaattgc ctgcctgcgt taaatatatg cctaagtaat
    21241 tgaatacttc aggcatatcc ggtcggattg ccagcgcttg cgaaaaatcg ttacgcgcta
    21301 atgccctcag accgagacta tcatacaaca ctccgcgctc atataaaagc tgtgcgcgtt
    21361 cgtcatcggt taaagcccga ctggcaagga tttgttccat acgtgccaga atcacttcct
    21421 gctgtaaagt cggttgcaat ggtaccgcga ggacttcact tttacgccag gaagtattac
    21481 tgcatcctgc aagcgtaagt gctgtcgcaa cgaaacacca gcgcaaaaaa ggcttcattt
    21541 cccactcccg aagaccacgg ttgaatgaac gtcctgttcc cggttgctaa caaggcgtcc
    21601 tgcccggtta aaagcccccc gccgcagcgg agggcaaatg gcaaccttac tcgccctgtt
    21661 cagcagccgg agcttccggt gctgcagcag gttgagactg ctcagtcgct tctttaatgc
    21721 tcagacggat acggccctgg cgatcaactt ccagaacttt caccggtact tcctgaccca
    21781 tctgcaggta atcggtcact ttctcaacgc gtttgtcagc gatttgagag atgtggacca
    21841 gaccttcttt accgccgccg atggcaacaa atgcgccaaa gtcaacgata cgggtcactt
    21901 taccagtgta gacgcggccc acttcgattt ctgcagtgat ctcttcgata cgacgaatag
    21961 catgtttcgc tttctcgccg tcggtcgctg caatcttcac agtaccgtca tcttcgattt
    22021 cgatggtggt gccagtttct tcggtcagag cacggattac agaaccgcct ttaccgataa
    22081 catctttgat cttgtccggg ttgatcttga tggtatggat acgcggtgcg aactcagaga
    22141 tatcgccacg cggcgcgttg atcgcctgtt ccattacgcc caggatatgc agacgcgcac
    22201 ctttagcctg gttcagcgca acctgcatga tctctttggt gataccttca attttgatat
    22261 ccatctgcag tgcagagata ccgtcgcggg aacctgcaac tttgaagtcc atatcgccca
    22321 ggtgatcttc gtcgcccaaa atgtcagaca gtacaacgta gttgtcgcct tctttcacca
    22381 gacccattgc gatacccgca acggcagctt tgatcggcac acctgcgtcc atcagcgcca
    22441 gagacgcgcc gcacacggaa gccatagaag aggaaccgtt ggattcagtg atttcagaca
    22501 caacacgtac ggtgtacggg aatttgtcca tatccggcat gactgccagc acgccgcgct
    22561 tcgccagacg accgtgacca atttcacgac gcttcggaga accgaccatg ccggtttcgc
    22621 ctacggagta cggagggaag ttgtagtgga acaggaaggt atcggtacgt tcgcccatca
    22681 gttcatcaag aacctgcgcg tcacgagcag tacccagcgt tgcggtaacc agcgcctgcg
    22741 tttcaccacg ggtgaacagc gcagaaccgt gagtacgcgg cagcacgcca gtacgcacat
    22801 ccagaccacg gatcatatct ttttcacgac cgtcgatacg cggttcgcct gccagtacgc
    22861 ggctacgaac aacgtttttc tcgatcgcgt gcagaatttc acccagttcg ttttcgtcca
    22921 gggtttcgtc ttcagcaagc agcgtcgcga tggtttcaga tttgatgaca tcaacctgcg
    22981 cataacgctc ttgtttgtcg gtgatgcggt aagcatcgct caggcgagct tcagccagtg
    23041 cagcaacgcg cgcgtttagc gcttcgttta ccggctccgg ctgccagtcc caacgcggtt
    23101 taccggcttc tttcaccagt tcattgatgt tctgaataac aacctgctgt tgttcatgac
    23161 cgaacactac tgcgcccagc atctggtctt cgctcagcag ttgagcttca gattcaacca
    23221 tcagtacagc ggcttcagta ccggcaacaa ccagatccag tttgctctct ttcagctcgt
    23281 cctgagtcgg gttcagtacg tactggtcat tgatgtaacc tacgcgggca gcaccaatcg
    23341 ggccattgaa cggaatacca gacagagaca gcgctgcgga agcaccaatc atcgcgacga
    23401 tatccgggtt aacttgcggg ttaacagaaa ccacggtggc gataacctga acttcgttga
    23461 cgaagccttc cgggaacagc gggcgaatcg ggcggtcaat cagacgcgcg atcagggttt
    23521 cgccttcgct tgggcggcct tcacgacgga agaagctacc cgggatacga ccagcagcgt
    23581 aggtacgctc ctgatagtta acggtcagtg ggaagaagtc ctgacctggt ttggcttttt
    23641 tctggccaac aacggtaacg aataccgcgg tgtcatccat gctaaccata acagcggcag
    23701 tagcctgacg agccatcatg ccggtttcca gagtcacggt gtgttggccg tactggaatt
    23761 tacgaacgat cggattaagc aatgtaatat cctttctctt tcttagacag taccttacgg
    23821 cactggtgtt aatacccgat cttctgcgca tcctcgcgac taatgacaac cctaacccag
    23881 ctctatgtgg gtaaagcctc tcattagccg cgcgaacctc tgcaacggaa gatcattcat
    23941 agcaacaata cattagtttc cagtgaattg ctgccgtcag cttgaaaaaa ggggccactc
    24001 aggccccctt ttctgaaact cgcaagaatt agcgacgcag acccaggcgc tcgatgagct
    24061 gggtgtaacg tgctacgtct ttacgtttca ggtagtcgag cagtttacga cgctgagaaa
    24121 ccatgcgcag cagaccacga cggctgtggt gatctttttt gtgctctgca aagtggccct
    24181 gcaggtggtt gatctgtgca gtcagcagtg ctacctgaac ttcggtagaa ccggtgtcgt
    24241 ttgcgtcacg accaaactca gaaacgattt tagctgttgc ttcagtactt agagacattt
    24301 taaaactcca aagtatatag aatgaaagga cgccgatctc taattcagcg atcccagtgt
    24361 acgttacgca aagtgttaaa caatttacgc gacgttaagc ggcagtattc tactcgtagc
    24421 gacctgttat cgcaagacgg ttaacattac gccgggtatt caaccaccag gcgacgaggc
    24481 gcaacgcggc cttcatcgtc aatttcgccc ataccgataa atttgccgtt ctcaccttcc
    24541 gtgacgcgaa ccagtccttc cagtggcgca ccagatgtac gaaccgggtt accatttttg
    24601 aagtaaacag aagacgttaa cggaagattc accaccggat agtccgaagc tggactgtcc
    24661 attggcatca gtaatggatc aagtaactcc gcggctggaa tatcctgctg ttcagcttgc
    24721 tcaacaagtt cacgcaggtg ctccagggtc accatccgtt caaccggata tttacttacc
    24781 gccagacggc gcaggtaaat aacatgcgcg ccacagccga gtttttcacc caggtcatca
    24841 atgatggtgc ggatataagt gccttttgag cagtgaattt ccagctccag ctcattgcct
    24901 tcatggcgaa taaacagcaa ttcataaacg gtaatcggac gcgcttcacg cggaacttca
    24961 atgccctgac gcgcatattc gtacagtttt ttgccctgat atttcagtgc tgaatacatc
    25021 gaagggatct gttcgatatc gccacggaaa gtatccagtg ccgctgccag ctgctctgcg
    25081 ctaaaggtta ccggacgttc ttcaacgatc tgtccgtcgg catcagaagt atcggtacgc
    25141 tgtccaagac gcgcaatgac ccgatagcgt ttgtcggagt ccagcagata ctgggaaaac
    25201 ttcgtcgctt ccccgaggca aatcggcaac atgccggtcg ccagcgggtc cagcgcaccg
    25261 gtatgcccgg cacggttggc gttatatata cgtttcactt tttgcagcgc atcgttgctg
    25321 gacataccct gaggtttatc cagcaacaaa acgccgttaa tgtcgcgacc gcgacgacga
    25381 ggacgactca ttagtcctcc ttgctgtcgt ccgggttaac acgacgttct tcgtcatgtt
    25441 tgaccacgct ggtcaccagg tttgacatgc gcatcccttc aaccagagag ttgtcgtaga
    25501 agaaggtcag ttccggcacg atacgcaggc gcatcgcttt ccccagcagg ctgcggatga
    25561 aaccagaagc ttcttgcaac gctttgatgc ccgctttaac cgcgtcttca tctttgtcgt
    25621 tgaggaacgt cacatatact ttggcatacg ccaggtcgcg agacatttcg acaccggaaa
    25681 cggtggtcat catgcccagg cgaggatctt taatttcacg ctgcaggatg agagcgatct
    25741 ctttttgcat ttcctgcgct acgcgctgcg ggcgaccaaa ttctttcgcc ataataaatt
    25801 ctcctgacaa aaaaggggct gttagcccct ttttaaaatt aatttcaggt ggaagggctg
    25861 ttcacgttga cctgataaga cgcgccagcg tcacatcagg caatccatgc cggatgcagc
    25921 gtaaacgcct tatcccgcat ggaaccctaa aaaccttaag caatggtacg ttggatctcg
    25981 atgatttcga atacttcgat cacatcgcca gtgcggacgt cgttgtagtt cttaacgccg
    26041 ataccacatt ccataccgtt acggacttcg ttaacgtcat ctttgaagcg gcgcagggac
    26101 tccagctcgc cttcgtagat aaccacgttg tcacgcagaa cgcggatcgg gttgtgacgt
    26161 ttaaccacac cttcggtaac catacagcct gcgatggcac caaatttcgg cgatttgaac
    26221 acgtcacgaa cttccgccag accgataatc tgctgtttca gttccggaga cagcataccg
    26281 ctcatcgccg ctttcacttc gtcaatcagg ttatagatga cggagtagta acgcagatcc
    26341 aggctttccg cttcaatcac tttacgtgca gaggcatcag cacgtacgtt aaagccaacc
    26401 aggatggcgt tggacgccgc agccagggtg gcgtcggttt cggtgatacc acctacgcca
    26461 gaaccgatga tcttcacttt aacttcgtca gtagacagtt tcagcaagga gtcggagatc
    26521 gcttcgacag aaccctgtac gtctgccttc aggacgatat tcacttcgtg aacttcgcct
    26581 tcggtcatgt tggcgaacat gttctcgagt ttagatttct gctgacgcgc cagtttaact
    26641 tcgcggaatt taccctgacg atagagtgca acttcacgcg ctttcttctc gtcacgtaca
    26701 acggtaactt catcacccgc agccggtacg ccggacaggc cgaggatttc caccggaatg
    26761 gacggacccg cttccagcac ttcctgaccc agttcgttac gcatcgcacg aacacgaccg
    26821 tattcgaagc cacacagaac gatatcgccc ttgtgcagag taccttcacg taccagaacg
    26881 gtagcaaccg gaccacgacc tttatcgagg aaggattcga taaccgcacc gctcgccata
    26941 cctttacgta ccgctttcag ctccagaact tccgcctgca gcaggatagc gtccagcagt
    27001 tcatcgatac cggtacccgc tttcgcagat acgtgtacga actggctttc accgccccac
    27061 tcttccggca ggatgccgta ctgggagagt tcgttcttaa cgcgatccgg atcagcttct
    27121 ggtttatcga tcttgttcac tgcaaccacc accggtacct gcgccgcttt cgcgtgctgg
    27181 attgcttcga tggtctgcgg catcacaccg tcgtcggcag caacaaccag gactacgatg
    27241 tccgttgcct gcgcaccacg agcacgcatt gaagtaaacg cggcgtgccc cggggtgtcc
    27301 aagaaggtga tcatgccgtt ttcagtttca acgtggtatg caccaatgtg ctgggtaatg
    27361 ccgcccgctt cgccagaggc cactttcgtt gaacgaatgt agtccagcag agaggtttta
    27421 ccgtggtcaa cgtgacccat gatggtcaca accggcgcgc gcggttcagc cgcagcaccc
    27481 gtgtcacggt cgctcattac cgcctcttcc agctcgtttt cacgacgcag gataacttta
    27541 tggcccatct cttcagcaac cagctgtgcg gtttcctgat cgataacctg gttgatggtt
    27601 gccattgcgc ccagtttcat catcgctttg atgacctgag agcctttaac cgccatcttg
    27661 ttcgccagtt cgccaacggt gatagtttcg ccgatcacaa cgtcacggtt aacggcctga
    27721 gcaggcttct ggaagccttg ctgcagcgaa gaacctttac gttttccgcc tttaccgcca
    27781 cgtactgctg cgcgtgcttc ttcacgatca gcttttgatt cagcgtgttt gttgcctttc
    27841 ttcggacgcg ctgctttcgc gttacgacca cggccacggc cgccttcgac ttcacgatcg
    27901 ctttcgtctt ctgcctggcg agcatgttga gaagtagtga cgtgataatc gctggaatct
    27961 tcagtcggtt ccgcgttatc agtccatttg ttttcttccg ccatacgacg tgcttcttca
    28021 gcaacgcgac gtgcttcttc ttcgagttta cgacgcgctt cttcttcagc tttacgcttg
    28081 agctctgcag cttcctgctc acggcgggct ttttcagcct gggcgttttt agtcatatcg
    28141 tcttgttgat tgctcacttt gtctttttcc gcagcttcac gtttcgcttg ttcagcagct
    28201 tcacgcttag cttgttctgc ggcctcacgt tcagcttttt gttgcgcctc gcgtttagcc
    28261 gattcttctg cctcacgacg ggcttgctct tccgcttcac gctgcgcttg ctcttccgct
    28321 gcaaggcgtt cagcctcttg cggatcgcgt ttcacaaagg tgcgtttctt gcggacttcg
    28381 atttgtaccg atttgctttt tccaccggta ccaggaatgt taagggtgct gcgtgtttta
    28441 cgttgcagcg tcaatttgtc cgggcctgaa tttttctgat tcaggtggtc aatcaaagtc
    28501 tgtttctctt gtgcagacac agagtcgtca gcagacttcc ggatacctgc atcagcaaat
    28561 tgctgtacca ggcgttccac ggaggtctgt cgctctgcgg ccagcgtttt aatcgttaca
    28621 tctgtcatgc tgttccttcc tgctacagtt tattacgctt cgtcaccgaa ccagcaaata
    28681 ttacgggcag ccataatcag tgctccggct ttttcgtcgg tcaacccttc gatatcagcc
    28741 agatcatcaa tgccctgttc ggcgagatct tccagcgtac aaacgccacg ggcggccagt
    28801 ttgaatgcca aatcacgatc taccccttca aggttcagca gatcgtcagc cggcttgtta
    28861 tcaccgaggc tttcttcctg ggcctgtgca atggtggcca gtgcattttt agcacgctcg
    28921 cgcagtgctt caacggtcgg ctcatcaagg ccttcgattt ccaacagctc tttcatcggc
    28981 acataggcca gttcttccag cgtcgagaag ccttcttcta ccagaacagt cgcgaagtct
    29041 tcgtcgatgt cgagatattt ggtgaaggtg tcgatcgctg cgtgcgcttc cgcctgatgc
    29101 ttagcctgca ggtcgtcaac ggtcatcacg ttgagttccc aaccgctcag ctgcgaagcc
    29161 agacgcacgt tctgaccgtt acggccaatc gcctgcgcca ggttaccggc ttcaacggcg
    29221 atatccatgg tgtgtttatc ttcatccacc acgatagaag caacgtctgc cggtgccatt
    29281 gcgttaatca cgaactgcgc cgggttatca tcccacagga cgatatcgat acgctcgcca
    29341 cccagttcag tagacaccgc ctgaacacgc gcgccacgca tacctacgca agcacctacc
    29401 ggatcgatac gtttatcgtt ggttttcacc gcgattttcg cacgagaacc cggatcgcga
    29461 gccgctgctt taatttcaat cacttcttcg ccgatttctg gcacttcaat acggaacagt
    29521 tcgatcagca tttccggctt ggaacgagtg acgaacagtt gcgcgccacg cgcttccggg
    29581 cgaacggaat agagcacgcc acgaacgcgg tcgccagggc ggaagttttc acgcggcagc
    29641 atatcttcgc gcaggatcac ggcttcagcg ttgttgccca gatccagaga gatgttgtcg
    29701 cggtttactt ttttcaccac gccggtgatg atttcacctt cgtgttcacg gaactgatca
    29761 accaccatcg cacgttcggc ttcacgcact ttctgcacga taacctgttt tgccgtctgg
    29821 gtagtgatac ggtcaaaggt aacagactca atctgatctt caacgtaatc gcccaggttc
    29881 aggctttcat cttcataacg tgcggcttca agggtgattt ccttggtcgg ctgggtgact
    29941 tcatcaacaa ctaaccagcg acggaaagtg tcaaaatcac cgcttttgcg atcgatctgt
    30001 acgcggacgt cgatctcttg ttcatatttt ttctttgttg ctgtcgccag cgcgctttcc
    30061 aatgcttcga aaatcttctc gcgaggtagc gccttttcat tggatacggc ttcaactaca
    30121 gccaaaattt ctttgttcat cgcgggcttt tcacctcatc cagactatta aaagtgggga
    30181 accaggttcg ccttctggat attactcagc gcgaacactt catctttacc ttcgacggta
    30241 actgtgatca tttcaccgtc taccgctttg ataacgccct gccatttacg acggttttgt
    30301 accgccatac ggagaaccag agtcacctct tctccgacaa aacgggcgta gtgttcagcc
    30361 gtgaacagtg ggcgatcgag acccggtgag gagacttcca ggttataagc aacggtgatg
    30421 ggatcttcaa catccagcac agcacttacc tggtggctca catcagcaca atcatcaaca
    30481 ttgatgccat cttcactatc aatatagatg cgcagtgtgg atgtgcgacc gcgaataaat
    30541 tcgatgccaa ccagttcaaa acccagggcc tcaactggcg cagtaatcat ctctgttaat
    30601 ttttgctcta atgtggacaa gcccaccccc aagacataaa aaaagggcct aaagcccagt
    30661 tattctgtag tcagataaca aaaaaccccg ataaatcggg gctttatata actgaaccct
    30721 ataaccgcaa ctgcggtctg gagcactttc cagaaggatt ttttcaaatc ccactacgaa
    30781 ggccgaagtc ttcacagtat atttgaaaaa ggactctaag ggaaagtggt tgcgggggcc
    30841 ggatttgaac cgacgacctt cgggttatga gcccgacgag ctaccaggct gctccacccc
    30901 gcgcctgaaa cgtggcaaat tctactcgtt ttgggtaaaa aatgcaaata ctgctgggat
    30961 ttggtgtacc gagacgggac gtaaaatctg caggcattat agtgatccac gccacatttt
    31021 gtcaacgttt attgctaatc atgtgaatga atatccagtt cactttcatt tgttgaatac
    31081 ttttgccttc tcctgctctc ccttaagcgc attattttac aaaaaacaca ctaaactctt
    31141 cctgtctccg ataaaagatg attaaatgaa aactcattta ttttgcataa aaattcagtg
    31201 agagcggaaa tccaggctca tcatcagtta attaagcagg gtgttatttt atgacgacga
    31261 ttctcaagca tctcccggta ggtcaacgta ttggtatcgc tttttctggc ggtctggaca
    31321 ccagtgccgc actgctgtgg atgcgacaaa agggagcggt tccttatgca tatactgcaa
    31381 acctgggcca gccagacgaa gaggattatg atgcgatccc tcgtcgtgcc atggaatacg
    31441 gcgcggagaa cgcacgtctg atcgactgcc gcaaacaact ggtggccgaa ggtattgccg
    31501 ctattcagtg tggcgcattt cataacacca ccggcggcct gacctatttc aacacgacgc
    31561 cgctgggccg cgccgtgact ggtaccatgc tggttgctgc gatgaaagaa gatggcgtga
    31621 atatctgggg tgacggtagc acctacaaag gaaacgatat cgaacgtttc tatcgttatg
    31681 gtctgctgac caatgctgaa ctgcagattt acaaaccgtg gcttgatact gactttattg
    31741 atgaactggg cggccgtcat gagatgtctg aatttatgat tgcctgcggt ttcgactaca
    31801 aaatgtctgt cgaaaaagcc tactccacag actccaacat gcttggtgca acgcatgaag
    31861 cgaaggatct ggaatacctc aactccagcg tcaaaatcgt caacccgatt atgggcgtga
    31921 aattctggga tgagagcgtg aagatcccgg cagaagaagt cacagtacgc tttgaacaag
    31981 gtcatccggt ggcgctgaac ggtaaaacct ttagcgacga cgtagaaatg atgctggaag
    32041 ctaaccgcat cggcggtcgt cacggcctgg gcatgagcga ccagattgaa aaccgtatca
    32101 tcgaagcgaa aagccgtggt atttacgaag ctccggggat ggcactgctg cacattgcgt
    32161 atgaacgcct gttgaccggt attcacaacg aagacaccat tgagcagtat cacgcgcatg
    32221 gtcgtcagtt gggccgtctg ctgtaccagg ggcgttggtt tgactcccag gcgctgatgc
    32281 tgcgtgactc tctgcaacgc tgggttgcca gccagatcac tggtgaagtt accctggagc
    32341 tgcgccgtgg gaacgattat tcaatcctga ataccgtctc agagaacctg acctacaagc
    32401 cagagcgtct gacgatggaa aaaggcgact cggtgttctc gccagatgat cgtattggtc
    32461 aattgaccat gcgtaacctg gatatcactg atacccgcga gaaacttttc ggttatgcca
    32521 aaactggcct gctttcctcc tctgccgctt caggcgtgcc gcaggtggag aatctggaaa
    32581 acaaaggcca gtaattcgac atcaaccctg cccttcaggg gtggggttac cttgcttatc
    32641 ctctgtaaac tcctttctga gcatcacata atcgaaaaca tcatggtttg catccacaac
    32701 ccgtgagtct cctttatagt gtgcaatcac ttcctcaagc gtttgcggct gttccggctt
    32761 tgttaccccc atccacgcat taataaggta attattgtaa gctgtcgaaa agatgttgtt
    32821 ttccgttgtg cgatccacgc catccccaag aacggggcta taccagataa acatcgggac
    32881 atgatatgcc tgctggctag cctccctgcc tccatgaaaa tagacgttct tcttcgtagg
    32941 gtcacgttcc aggccgtggt cggcaaaata catgaccgag gcgcggcgat cttttaataa
    33001 ttcaaaaacc tgacctagca aactatctgt gtaatgaatg gagttgtcat agcaggcatc
    33061 ctgatcgtcc tgcggttgaa acacggcgct ggattgcgga taggcgctac aagccggttc
    33121 atggcttcca tttaaatgaa gaacaatcag tttcttttgc tgcgtatttt gctgtaatgc
    33181 ttgcgataaa tgcggcaaca acaattcatc aaatcctctg acataaactg tttccatggc
    33241 gcgcatggcg atactggtaa ctgctgtacc attctgccga aaagcggatt gcgagcttag
    33301 ccagaaagtc tgaaatcctg cttgattagc catattaata atgttgtcgg ggtaattatg
    33361 aatgtcatga ctcaaaacag aatcagcagt taaagaaagg ggaaccgaca gcgcagtgta
    33421 aggtgcgccg cttattgctt gattaaacag tttgatctgt tttctttgtg cttcaacttg
    33481 cggtgtcgta gagcgtgtat atccatacaa agacatattg tcgacacgta cagactcccc
    33541 cacaatcaac acgtaggtat caatacctgt atccctgact gataattgaa aatacggcac
    33601 cgtgtttgca attgagagta atctttgatg ctctttcgct gctaaagcaa aatagttgag
    33661 attgaaaaac ggcgtatagg tagcaaatcg cgacgctagt atatatggac tgaacgcttt
    33721 tttatttttt gcatctttat aagcaaattg acaagcggaa aataaactgc ccgaaatgac
    33781 aatcagcaat aatattcctg tcactttttt tgtcggcaag gaaacatcat attttattat
    33841 tactgccaaa aaaagaaggg ataaaaaagc aaaggcacat agataaggga tatacatccc
    33901 cagcattttg acaacttcat ccggatcact ctggagcaca ctaatcgcaa atccatcatt
    33961 gaaagttgta ccaaaggtac accatgaata gaggctaata ctcatgtctg ccgcagtcag
    34021 taacacaaat ggtgcggcaa caagcaggcg aagcggaagg gatgatatac gttttacaac
    34081 caggatggtc agaacgaaga acagcaagcg ctgaaccata tgcgctccgg aagaagcgac
    34141 taagttcgta ataccaaaaa caataacaca aagatacaac aaccaatgag atttaaaagt
    34201 tctagcaaat ttgttgaata ctgtcatcca gaaatccaag ttcacaacca atataaacaa
    34261 ttatcaacaa tgtttaattt tatatcagac atgtttttca actctgatcc atatcagaac
    34321 gaaacactgt tagttttttc tttttaaatg atgcggccat tgcgttctca gtaattaaat
    34381 aacattatca atgcgtctct aaacattacg cagaacgtag ccatcagtcg ttatactgac
    34441 aggagcagga tggtttatcg agaagtaaac atatccgtat tagtaccgga actggagttg
    34501 acacaataaa gtgccaatta tgtcagtaga agggaaaaat ttataactaa ggcgtaccgg
    34561 caccatcgtt tcaaggtacc agctacgagt aaagcaactg gacgagatac agatacctga
    34621 caaccattcc tcagaccagg accaaaacga aaaaagacgc ttttcagcgt ctcttttctg
    34681 gaatttggta ccgaggacgg gacttgaacc cgtaagccct attgggcact accacctcaa
    34741 ggtagcgtgt ctaccaattc caccacctcg gcacggatac tactttttag ttcgggatat
    34801 cgctggtcgg cttagccgga gcagctggct gagtttgttc ggttttcgcc ggtgcactca
    34861 gattttccca ttcgctacct ttattggttt tgttgctatt gatgttaccc agcaccagac
    34921 tgatgatgaa gaataacgtt gccagcagcg ccgtcatgcg ggtcatgaag ttaccagaac
    34981 cacttgaacc aaacagcgta gcggaagcgc ctgctccgaa ggaggctccc atatcagcgc
    35041 ctttaccttg ctgcagcatg atcagaccaa caaggccaat tgccacaata aggaaaacta
    35101 ctaaaagagc ttcatacata atcaacctgt tccttgcgga gttgccgcgt accaatgctt
    35161 caaccaataa agcgggagtt tttaatcttt cccactgaag cgggtgtgaa tactaaccaa
    35221 agcgaatgac cttcgcaagg gcaattttat cgcattgtat caactgcgga aaaaaacagc
    35281 aaaaccgatg tgttcgctga gaaaaaaggc gacaatcgcc gcctttttag ccagttatct
    35341 aacgctttaa acggctttta ctgcatcggc gatgcggtgt gcaaattcag tcacctgcgc
    35401 ttcgtcttcg ccttccacca tcacgcgaat taacggttcg gtgccggatt tacgcagcaa
    35461 cacgcgtcca cggttgccca gcgcagcttc aacctctgcg gtcacggctt taactgactc
    35521 atgctcaagt ggatcgccgc tacctgcggt gtaacgtacg ttaaccagaa tctgcgggaa
    35581 cattttcatg ccgctgcaaa ggtcgtgcag gctcatatgg ttacgtgcca tcgccgccag
    35641 cacctgcaag ccagcaacga tgccgtcacc ggtagtagtt ttatccagca ggatcacatg
    35701 accggaattc tctgcaccga tacgccagcc tttctcctgc attttttcca gtacgtagcg
    35761 gtcacccact ttcgcgcgcg caaatggaat tcctaactgt ttcagcgcca gttcaagccc
    35821 catgttgctc atcaatgtac ccacagcgcc accacgcagc tggccctgac gaagaccttc
    35881 acgcgcgatg atatacatga tctgatcgcc atcgacttta ttgccttcat ggtcaaccat
    35941 aatcacgcga tcgccatcgc cgtcgaaggc aataccgaga tccgcttttt cagccagcac
    36001 acgagcctgg agcgcgcgaa cgtcggtagc ccccacttcg gcattgatgt ttacaccgtt
    36061 tggctcacaa ccgatagcga taacgttcgc ccccagttcg cgcagcacgt tcggcgcgat
    36121 gtgataagtc gcaccgtttg cacaatccac cacaatcttc agttcactga ggctaagttc
    36181 gttcgggaac gtggctttgc aaaactcgat atagcgaccc gcggcatcaa cgatacggct
    36241 ggctttaccc agttctgccg aatcaacgca gctgatctcc ttttccattt ccgcttcgat
    36301 ggcctcttct accgcatccg gcagtttggt gccgtcgata gagaagaatt taatgccatt
    36361 atcgtagaac gggttatgcg atgcagatat cacaattccg gcctctgcgc ggaaggtacg
    36421 cgtcagataa gccacggccg gtgttggcat cgggccagtg aagagtgcgg aaaggcccgc
    36481 tgccgccaga cccgcttcca gtgctgactc cagcatatag ccagaaatac gcgtgtcttt
    36541 accaataata atcttacggg agccgtggcg cgccagcact ttacccgcgg cccaacccag
    36601 cttaagcaca aaatcaggtg tgatcggcgc atcccctaca cgaccacgaa tcccatcggt
    36661 accgaaatat ttacgattac tcatagcgtt tgttttcctt tgcagacaga gtggcttcca
    36721 ccacccgcat cgcttctacg gtttctttga cgtcatgaac acgaatgatg tgcgcgcctt
    36781 gcattgcggc aatgaccgca caggccagac taccgctcag gcgctcggac ggccccacgt
    36841 tcagcagctg cccaatcatc gattttcgtg acatacccac caacagcggc aggttgaaat
    36901 ggtgaaattc agccaggcgc gccagtaatg aatagttatg ggagagattt ttaccgaaac
    36961 cgaatccggg gtcgagcaac aatttctctt ttgcgatacc cgcctgctcg caacgtgcta
    37021 tttgctcaat aaagtagcga ttcacttctg caaagacatc gtcatacttc ggagcttcct
    37081 gcatggtttt tggatttccc tgcatatgca tcagacaaac cggtaaaccg gtttctgcag
    37141 ccgcctccag agcgccaggt tcggaaaggg agcggatatc attaataatg tgagcgccaa
    37201 ctttcgctga ctcacggatg acttctggtt tggatgtatc gactgagatc cagacttcga
    37261 agcgttgagc aattgcctca accacaggaa taacacgttg caactcttct tcaacgctaa
    37321 cttccgccgc ccctgggcgc gtggactcgc caccaacgtc aatgatcgtc gcgccagcgt
    37381 tgatcatcag attcgcatgt ttcaccgcat ctatcagcga gttatgcgtg ccaccatccg
    37441 aaaaggaatc aggcgtgacg ttgaggatcc ccattacgtg aggatggcta aggtccagtg
    37501 aagtaccctg ggcaaagagt ttcatgatgt tatccctggt atgaattgat aagaaaaaac
    37561 cccggagcac gccccggggt tttcggtaca aatacagtca tctgatgcgg gaacttactt
    37621 gtcgcctaac tgctctgaca tggtgttacc cgggttcggc gtacgcggtt catcaaccgg
    37681 acgaggagcc tttggactac cattgtcgcc agaattgtta gaagcgcctg gttcttccca
    37741 gcccgctggc ggacgtacat cgcgacgtgc catcaggtca tcaatctgcg gtgcgtcgat
    37801 agtctcatat ttcatgagag catctttcat cgcatgcaga atatccatat tgtcggtcag
    37861 aagctgacgc gcacgattat agttacgctc aatcagtgct ttcacttcct ggtcgatgat
    37921 acgtgcagtt tcatcggaca tatgtttcgc tttcgctacg ctacggccga ggaacacttc
    37981 accttcttct tccgcgtaca gcagtggacc caatttctca gagaagcccc actgagtcac
    38041 catgttacgt gccaggttgg tcgcaacttt aatatcgttg gacgcaccgg tagatacatg
    38101 ttccggcccg tagatgatct cttctgccag acgaccaccg tacagcgtag aaatctggct
    38161 ttccagtttc tgacggctgg cgctgattgc gtcgccctca ggcaagaaga aagtcacacc
    38221 cagcgcacga ccgcgtggga taatcgtcac tttgtgcacc ggatcgtgtt ccggcaccag
    38281 gcgaccgata atcgcatgac ccgcttcgtg gtaagccgtc gattctttct gcgcttccgt
    38341 catcaccatg gagcgacgtt ccgcacccat catgattttg tctttcgctt tctcgaactc
    38401 aaccatcgac acaacgcgtt tgttgccacg agcagcgaac agtgccgctt cgttcaccag
    38461 gttcgccagg tcagcaccgg agaaaccagg agtaccacgg gcaatgattg ccgcgtcgat
    38521 atcgggtgcc aatggtacgc gacgcatgtg aactttcagg atctgctcac gaccgcgaac
    38581 atctggcaag ccgaccacaa cctgacggtc gaaacggcca ggacgcagca gggccgggtc
    38641 gagaacgtcc ggacggttag tcgcggcgat aacgatgata ccttcgttac cttcgaagcc
    38701 atccatctca accagcatct ggttcagagt ctgttcacgt tcatcgtgac caccgcccag
    38761 accagcgcca cgctggcggc ctacggcgtc gatttcatcg ataaagatga tgcacggtgc
    38821 cgctttcttc gcctgttcga acatgtcacg aacacgggat gcacccacac cgacgaacat
    38881 ttctacgaag tcagaaccgg agatagtaaa gaacggaact ttcgcttcgc ctgcaatcgc
    38941 tttcgccagc agcgttttac cggtacccgg aggaccgacc atcaagacgc ctttcgggat
    39001 cttaccgccg agtttctgga agcggctcgg ctcgcgcaga tactcaacca gttcagcaac
    39061 ttcttctttt gcttcgtcgc agcccgcaac gtcagcaaag gtcgttttga tctgatcttc
    39121 cgtcagcatg cgcgctttgc tcttaccaaa cgacatggca cctttgccac cgccgccctg
    39181 catttgacgc atgaagaaga tccagacacc aatcagcaac agcatcggga accaggagat
    39241 gaagatagaa gccagcaggc ttggttcttc aggcggttca ccgacaacct tgacgttctt
    39301 ggtcaacagg ttatccagta atttcggatc ctgaaccgga atgtaagtgg tataacggtt
    39361 actatctttc ttggtaacgt tgatttcacg tccgttgata cgcgcttcac gaacctggtc
    39421 gttattgacc tcttgtagga aggtagagta atccacctta cggccattag actcgctggg
    39481 cccaaagctc tggaatactg acatcagcac aacggcaatg accagccaga gtattaggtt
    39541 tttcgccatg tcactcaagg gattaacctc ttattacaac tgtgttaaaa acagcgtcag
    39601 gatactctat atccagcatc tttcaaactt tcgtctgaaa tctcccggtt agggtttacg
    39661 cccggtcgct acaatataca cttcccgcga acgtgcacga gaagagtccg gcttacgaac
    39721 tttgaccttc gtaaacaggg agcgaatttc ccttagatac tcatcgaaac cttcgccctg
    39781 gaacaccttc actacaaaac tgccacctgg cgctaataca tcacgacaca tttctagcgc
    39841 cagttccacc agatacatgg cacgggggat atccaccgcc ggtgttccgc tcatgtttgg
    39901 tgccatatcg gacatgacaa cctggacttt gctgtcgcca acgcgctcca gcagtgcttt
    39961 catcaccagt tcatcacgaa aatcgccctg aagaaagtcc acaccaacga taggatccat
    40021 aggtaaaaga tcgcaagcga tgatgcggcc tttgccgcca atttgggtga ccacatattg
    40081 tgaccaacca cccggagcag caccaaggtc gacaaccgtc attcccggtt taaagagttt
    40141 gtcactttgc tgtatttcat caagtttaaa ccaggcacgg gaacgtaacc cctttttctg
    40201 tgcctgttga acatatttat cgctaaagtg ttcctgaagc cagcggctgg agctggcaga
    40261 acgcttctta cctgtcattt aactttccca tggggataac tcatcgtaac caattgcgta
    40321 aatttttacg cgcctatttg gtgatatatg ggagatggcg gtagaatgac ccgttttcaa
    40381 tcccaacgta agcaaaaaat acgatgaatc tgagtactaa acaaaaacag cacctgaaag
    40441 gtctggcaca tccgctcaag ccagttgttc tgcttggcag taatggtttg accgaagggg
    40501 tgctggccga gattgaacaa gcgttagagc accatgaact catcaaggtg aaaatcgcca
    40561 ccgaagatcg cgaaactaaa accttgatcg tggaagctat cgtgcgcgaa accggcgcct
    40621 gtaatgtaca ggtcatcggt aaaacgctgg tgctttatcg cccaactaaa gaacgtaaaa
    40681 tctcgctgcc acgctaagat tatcctaaag ttacacacat ttgctgtgta aaacgagggg
    40741 ttttccgcag gcaggagagc aaaatgccac gctctgttcg ttgataaaag gccgcatagc
    40801 ggcctttttc ctttctttac aatacatcaa catcttgagt attgggtaat tcttacaggt
    40861 attccacctt aattacttca aattctactt cgccgcccgg cgttttgatg accacaacat
    40921 catcttcttc tttgccgatc aggccacgag caataggcga gtttacagaa atcaggtttt
    40981 gtttaaagtc agcttcgtca tcgccaacga tgcgataagt ctgttcttcg tcagaatcca
    41041 gattcagcac cgttacggta gcaccaaaaa taacgcgccc attgttgggc attttggtga
    41101 catcaatcac ctgcgcgttc gacagcttgg cttcgatgtc tttaatacgg ccttcgcaga
    41161 aaccctgctg ttcacgagct gcgtggtatt cggcgttttc tttcaggtcg ccatgctcac
    41221 gcgcttccgc gatagcagca atgatttcag gacggcgcac agatttcaga aaatccagct
    41281 cttcgcgtaa tttttcagcg ccgcgtaagg tcatcggaat agcttgcatt tgttatacct
    41341 cttgaatatt cctgataggg caagtcttca cccaccccgg ctgttcggcc tgcccggcat
    41401 aactccttac cgggaccaga agcaaaaaaa taccgacccg ggtacaagtc ccaggtcagc
    41461 tacaattcac attttgatag tcattttacc ctgaagttcc cgaagggtca tcgtttactt
    41521 tatagggcgt tgcgccgtag tatgacggct cgattccagg ttgttagcgc gagattatgc
    41581 gattttccag atttatcatc ggattgacca gctgtatagc gttcagtgtt caggccgcaa
    41641 atgttgatga gtacattact caactccccg ctggtgccaa ccttgccctg atggtgcaaa
    41701 aagtcggcgc gtcggccccc gctattgatt accacagtca gcagatggcg ctgcctgcca
    41761 gtacccagaa agtgattact gcgctggcgg cgttgattca actcggcccc gattttcgtt
    41821 ttaccacgac gcttgaaacc aaaggcaatg tggaaaacgg cgtacttaag ggtgacttag
    41881 tggcgcgatt tggtgccgat ccgacgttaa aacgtcagga tattcgcaat atggtcgcga
    41941 ctttgaaaaa atctggcgtc aaccaaatcg atggcaatgt gttgatagat acctccattt
    42001 tcgccagcca cgataaagcc cccggctggc catggaatga catgacacaa tgctttagcg
    42061 ctccgcctgc cgccgccata gttgaccgca actgtttctc cgtctcgctc tacagtgccc
    42121 caaagcctgg tgatatggct tttatacgcg tggcatctta ttaccccgtt acgatgttca
    42181 gccaggtacg caccctcccc cgtggttctg ccgaagcgca atactgcgaa ctggatgtgg
    42241 tgccaggcga cctgaaccgc tttacgctga cgggatgcct gccacaacgt tctgagccgc
    42301 tcccgttggc ttttgccgtg caggatggag ccagctatgc cggtgcaatt ctgaaagatg
    42361 agttaaaaca ggcgggtatc acctggagcg gaacactgct gcgccagact caggttaacg
    42421 aacctggaac ggtagttgcc agtaaacagt cggccccgct gcacgatctg cttaagatta
    42481 tgctgaaaaa gtcggacaac atgatcgccg atacggtttt ccgcatgata ggccatgcgc
    42541 gcttcaatgt gcctggaaca tggcgggccg ggtcggacgc cgtgcgtcag atcctgcgcc
    42601 agcaagccgg tgtcgatatt ggaaacacca ttattgccga tggttcaggg ctttcgcggc
    42661 ataacctgat tgcccccgcc accatgatgc aggtgctgca atacattgcc caacacgaca
    42721 atgaacttaa ctttatctcc atgctgccgc tggcgggcta tgacggctct ttgcagtacc
    42781 gtgcaggtct gcatcaggcg ggcgtggatg gaaaagtctc agcgaaaacc ggttcgttgc
    42841 agggggtata taacctggcg ggattcatta ccacagcgag cgggcaacga atggcgtttg
    42901 tgcaatatct ttctggctat gcagtagaac ctgcggatca gcgtaatcgc cgtattccgt
    42961 tagtgcgttt tgaaagccgt ttgtataaag atatttatca gaacaattag tcaaaaagaa
    43021 accccggcac atggccgggg cttcagatta ttgacaaagt gcgctttgtt tatgccggat
    43081 gcggcgtaaa cgccttatcc ggcctacaaa atcgtgcaaa ttcaacatat tgcaattctc
    43141 ttgtaggcct gataagcgta gcgcatcagg ctgatttggc gtttatcatc agtgattaac
    43201 gcttgtaaat gaactcaacg ccttcttcgt cgtcttcgtc ccagtcgtca tcccagtctt
    43261 catcatcctc ttcagcaatc tcttcaagct gctggcgatg ataatcatcc cacatgaatt
    43321 cgactttctc tggctgtttc gcttcttcag cctgcacgac cgggttttca atgataaagg
    43381 tcatcacatc ccagcagaga tctttcacgc ccagtccact cgccgcagag atcagataat
    43441 atttatcttc ccagcccagc gcctcagcga tcgctttcgc tttctcttcg gcttctacct
    43501 tatccagcag atcgatcttg ttgaacacta accaacgcgg tttcgtcgcc agatcctggc
    43561 tgtatttttc cagctcgctg ataataatac gcgcgttttc aaccggatcg gtgccgtcaa
    43621 tcggatcgat atcgatgagg tgcaacagga cgcggcaacg ttccaggtgc ttcaggaagc
    43681 gaatgcccag acctgcgcct tccgcagcgc cttcaatcag tcctggaata tcggcaacaa
    43741 cgaagctctt ttcgttgtcc attcgtacca cacccagact tggcaccaga gtggtaaacg
    43801 gataatccgc cactttcggt ttagccgccg ataccgcacg aataaaggtc gatttacccg
    43861 cgtttggcat ccccaacata ccgacgtcag ccagcagcat cagctccagc agcagctcgc
    43921 gcttatcgcc cggcgtgccg ttggttttct gccgcggtgt acggttaacg gacgatttga
    43981 aacgggtatt gcccagaccg tgccagccgc ccttagcaac cagcagacgc tgaccgtgtt
    44041 tggtcatatc gcccatggtt tcaccagtac cctggtcgat tacacgcgta cctaccggca
    44101 ctttaatcgt cacgtcttta ccgcgcttac cggtacagtc gcggcttgcg ccattctgac
    44161 cgcgctctgc acggaaagat ttttcaaaac gataatcgat aagcgtgttc aggttctcgt
    44221 cggcttccat ccatacgtca ccaccatcac cgccgtcgcc gccatccggg ccgcctttcg
    44281 gaatatactt ttcgcggcgg aagctcacgc aaccattacc gccatcacct gcaacgacca
    44341 gaatcgatgc ttcatcaaca aacttcattt tattctccgt aaatcattcg cctgcgcggg
    44401 gttgcgatac caccgttgta tgcttacgta atccgcccca aatacgatga ccaatggcgg
    44461 aatacatcgc gcccgcaacc acgacaaacg caccgagata acctaaaagg tttaacatcg
    44521 gtctggcgaa gaaatcgggc caggccagtg ataaaagatc tgaaaaaaac agcgtaaaca
    44581 gtggggtgag cgtgatgatc gcgctcacct gcgctgcctg ccagcgagcc atcgcttccg
    44641 ccagggcgcc atatcctacc aaggtattca gtccgcaaaa aattaaacat gcgagctgcc
    44701 agtggctaag ctgcgctatc actccaggct ttgccagagg gaagagcgca attgtacata
    44761 aagtgtacag taaaaacagg atctgcggtg aggccagccg acgcaataaa accttttgcg
    44821 ccacgccata actcacccaa accgtcgccg caccgacccc aaagataact ccccaggtgt
    44881 aatcggtgag ctttgtaaat atctcgacca gactggtgtt aaaaaacatc accaggccgc
    44941 tcaggagcat caatgcccct acaacctgag tgctgcgcat tttctctttg aggataaata
    45001 cgctggcaac catcatgcca actggcgaga gttgcccaat cacctgcgaa gcggtcggac
    45061 tcaggtattg caaggatgag ctgaacagga tgaagttccc aaacagcccg gcggtcgcca
    45121 ctgccaacaa aatcaaccag cgtggcttac gaaacacgcg taatggcggc aacctcttct
    45181 tcaccgcaag aatggcaccc aggccaatac tcgccatcaa gaaacggtaa aacacgattg
    45241 tcggaggttc catcacctcc agcacctgct tcattgcgat tggcaacgcc ccccagcaaa
    45301 ttgctgtggt gagcgccaaa agaatgccaa tgcctgcctg ctgcttcata ccgtattccc
    45361 tgcaaagcgc atttgcggat taacgtcgca ccatgcgcat ttttaccggt tatcgaatgt
    45421 aaaaagcccc gcaacgtgtt gcggggcttt catccgttac cgggacgcga aaaacttatt
    45481 cagcttcgat gctgataaat ttacggtttt tcgggccttt aacttcgaat ttcactttac
    45541 cgtctgcttt agcaaacaga gtgtggtcac gaccgcaacc tacgttagcg ccagcgtgga
    45601 atttggtacc acgttgacga acgatgatgc tacccgccag aacggattcg ccaccgaaac
    45661 gcttaacgcc caggcgttta gcttctgaat cgcgaccgtt acgtgtggag ccgccagcct
    45721 ttttatgtgc catttgaaat ctctcctcag gtcttaggcg ctgatgccag taattttcac
    45781 atcagtgaac cactgacgat ggccctgctg cttacgatag tgtttacgac gacgaaactt
    45841 aacgatttta actttctcgc cacgaccgtg agcaacaact tcagctttga ttacgccgcc
    45901 atcaacgaaa ggaacgccga ttttgacttc ttcaccgttt gcgatcatca gcacttcagc
    45961 gaactcaaca gtttcgccag ttgcgatgtc cagcttttcc aggcgaacgg tctgaccttc
    46021 gcttactcgg tgttgtttac caccactttg gaaaaccgcg tacatataaa actccgcttc
    46081 cgcgcacacc ttttcaatga ttcagagtgc gctataaata ttcacaatag ggcgcgaata
    46141 ttacgcaaaa cgcacgcctt tgacaagtgc tacagtcaat acacgaagaa aaaaaacaca
    46201 acttgtacgg taacgtttat ctgtgccatt ttttcagtac aatcacccta tattcctaac
    46261 cataaaccct aagttgcctt tgttcacagt aaggtaatcg gggcgaaaag cccggctttt
    46321 gcgatgaatt tagaaaaaat caatgagtta accgcgcaag atatggcggg tgttaatgcg
    46381 gcaatccttg agcagcttaa ttccgacgtc caactgatca atcagttagg ctattacatc
    46441 gtcagcggcg gcggtaaacg tattcgtccg atgattgctg tactggctgc acgagctgtt
    46501 ggctatgagg gaaatgcgca tgtcaccatt gctgccctga tcgagtttat ccacacggcg
    46561 actctgctac acgacgacgt tgtggatgaa tcagatatgc gcaggggtaa agctaccgcc
    46621 aacgccgcat ttggcaatgc cgccagcgtg ctggtaggcg attttattta tacccgcgct
    46681 ttccagatga tgaccagcct cggttcgctc aaagtgctgg aagtcatgtc agaagccgta
    46741 aacgtcatcg cagaaggtga agttctgcaa ctgatgaacg ttaacgatcc ggacatcact
    46801 gaagaaaact acatgcgcgt tatctatagc aaaaccgcgc gtctgtttga ggctgccgcg
    46861 cagtgttccg ggattctggc tggctgtacg ccggaggagg agaaaggcct gcaggattat
    46921 gggcgctatc tcggcactgc tttccagttg atcgacgatt tactcgatta caatgccgat
    46981 ggcgaacagt taggtaaaaa tgtcggcgac gatctgaacg aaggtaaacc gacgctgccg
    47041 ctgctgcatg cgatgcatca tggcacacca gaacaggcac agatgatccg taccgccatc
    47101 gaacagggta acggtcgcca tcttctggaa ccggttctgg aagcaatgaa cgcttgtgga
    47161 tctcttgaat ggacgcgtca gcgtgccgag gaagaagcag acaaagccat cgcagcgtta
    47221 caggtgctcc cggacacccc ttggcgagaa gcactcatcg gcctcgcgca catcgctgtt
    47281 caacgcgatc gttaatcccc tcccctcatc ccgcgcagcg cgcgggatgg ttccagtaag
    47341 ttccataaaa acacttattc agctctataa cacctgaaaa atagggatgt gcatctttat
    47401 atattctgaa tattcacact ctttacagga actttttaga gcaataggcc atcaggagta
    47461 tagtgatgct cgacagaaga agtgttctga atgaaagcga ctaacttaag gagtgaggaa
    47521 aaatggaaag taatttcatt gactggcatc ccgctgacat cattgcgggt ttgcgcaaga
    47581 agggaacgtc aatggcggcg gaatctcgca gaaatggttt gagttcctca acgctggcga
    47641 atgcattatc gcgcccatgg ccgaaaggag agatgattat tgcgaaagcc ctgggaactg
    47701 acccctgggt tatctggcca tcacgctacc atgatccgca gacccatgag tttatcgaca
    47761 gaacgcagtt gatgcgtagc tacactaaac cgaaaaaatg agtggtctgg cggtagcccc
    47821 gcgaacgggg ctgccagctc tcagacgatt attcgccttt cacacgctca atatttgcac
    47881 ctaaagcgcg cagtttgtct tcaatgcgtt cgtagccacg atcgatgtga taaatacgat
    47941 caaccaccgt cgtcccttcc gcaatacagc cagccagcac caggcttgct gatgcacgca
    48001 gatcggttgc cataacctgt gcgccagaaa gtttttcaac accgtgacaa ataacggtat
    48061 tgctttcgat ttcggcgtgc gcgcccatac ggctcagctc tggcacatgc ataaagcggt
    48121 tttcaaagac cgtttcggtg ataaacccgg tcccttctgc caccaggttc aacagcgtga
    48181 actgggcctg catatcggtc gggaatgccg gatgcggcgc ggtacgtacg ttaacagcct
    48241 tcggacgttt gccatgcata tccaggctaa tccagtcttc gccgacttcg atgtccgctc
    48301 cagcgtcacg cagtttcgcc agcacggcgt cgagagtatc tggctgcgcg ttacggcaga
    48361 taattttgcc gcgagaaatc gccgccgcca ccaggaaagt accggtttcg atacgatccg
    48421 gcagaacgcg atagacaccg ccgcctaaac gttccacacc ttcgatgacg atacgatcgg
    48481 tgccctgacc gctaattttc gcacccagcg taatcaggaa gttcgcggta tcgacgattt
    48541 ccggttcacg cgctgcgttt tcaataatcg tggtgccttc cgccagggtt gcagcacaca
    48601 tgatggtcac cgttgcgcca acgctgactt tatccatcac gatatgtgca cctttcaaac
    48661 gaccatcgac ggaagcttta acgtaacctt cttccagttt gatggtcgcg cctaattgtt
    48721 cgaggccaga aatgtgtaga tcaaccggac gcgcaccgat cgtacaaccg ccaggtagtg
    48781 aaacttgccc ctgaccaaag cgcgctacca gcggccccag cgcccagata gaagcacgca
    48841 tggttttaac cagatcgtaa ggtgcgcaga atacattaac gtcgcgggca tcaatatgca
    48901 cagaaccatt acgttctact ttcgcaccca gctggcttag cagcttcatt gatgtatcga
    48961 cgtctttcag tttcgggacg ttctggatct ctaccggttc ttccgccagt agtgcggcaa
    49021 aaaggatagg cagagcagca tttttagcgc cggaaattgt gacttcgccc tggagcttcg
    49081 ttggcccctg aacacgaaat ttatccattt agtttgttct cagttaacaa ttcatatccg
    49141 ctaccggcga atcgcccata gctcaaaagc cgttcagttt gcgatcgcgc gcccactccg
    49201 caggggtata cgctttgatc gacacagcat gaatgcggtt atccgcaata tattccatca
    49261 gcggaccata gaccgtctgc tgttttttaa cccgactcat gccgtcaaac aactcaccca
    49321 cggcaataac ctgaaagtgg ctgccatcgc cggaaacgtg gacttcctgg agggagagag
    49381 cgttcatcaa cacgctctga atttcattat tttccatggg atcttcaatc atcagttaat
    49441 aaaccagcga aacatcttag agcaaagttg cgctggcata aataagcaaa aagcctcgct
    49501 gataaatcag acaaggctcg acttgcaggc aggtttgccg gacaggcggt taacgccata
    49561 tccggcctga aaaaatttaa cgaggcagaa catcagcagg caaattatac aatttcgcca
    49621 gggtatacac tttgtcgttt accccctgaa gcgtcacatt gttgccctgc tttttcgcca
    49681 gatcgataag atggagcagc agtgccagtc cccccgtatc cacgcgggag acacggctaa
    49741 gatcgatgca ggtaatcccc ttcaccgctt cctcacgcat ttcccaaagc ggtagcaaaa
    49801 cgtcctgatc cagctctccg gataacgcca gcgtgtcacc cgtctgcatc cagctcagtg
    49861 actcgctcat tattttttct cttccagagt gattttctgt tgagaaatcg atttcagttg
    49921 cgcagtcagg ccgtcgatac ctttggtacg cagcagcgtt ccccactcgt tttgtttggt
    49981 ggtgatcata ctgacgcctt cagcaatcat gtcgtaagcc tgccaattgc ccgtctggga
    50041 gtttttacgc cactggaagt ccagacgcac cggcggacgg ccattcgggt caataatggt
    50101 aacgcgaata ggcacaatgg ttttatcgcc cagcggctgt tctggcgcaa tctgataggt
    50161 ttgaccgtga tacatcgcca gcgcctgacc gtaagcctgc ttcaggtact cacggaaagc
    50221 ggcaaagtag gcttcacgtt gagcaggggt cgcactcttg taatactggc ccagcaccag
    50281 cgcaccggcg tatttcacct gtacgtatgg cagcagttcc tgatcaacaa tggtacgcag
    50341 ataatccggg ttggcccgaa tttgcggttg ctcattcttc aggcgatcga acgttttctg
    50401 cgccgcctcg tccatcagct tatacggatt ggtctggtct gccgcggttg ccgcactcag
    50461 aggtgcaatc accagcaaag cgaccatcat taaacgttta aacatgcgtc ggttctcctg
    50521 aaattatttc gttgtaccca caggttcagt ggtttcatta ttacctggcg cagcagctgg
    50581 cgcatcgcca ctattcttat tgtcatcgcc tttactaccg taaaggaact gaccaatgag
    50641 atcttccagc accatcgcag acttagtgtc ctgaattgta tcgccatcct tcaggatagc
    50701 agtccccagt tccgggtctt caaaaccgac gtttaatgcc agatattgtt cccccagcag
    50761 gccggaagta cgaatgctca gcgaactggt atctggaatg tggttataac gttgttcaat
    50821 ttccagcgtt acgcgcggca gataggtttt cgggtccagc gtaatatccg ccacccgacc
    50881 cacaacaacg ccaccaatac tgaccggaga gcgcgctttc aggccgccaa tgttatcgaa
    50941 cgtcgcataa agcgtgtagg tcggttcagt acgtatggac gtcacgttcg ccgccttcag
    51001 gcaaacaaac agcgccgcca gcagtgctgc taataaaaag atacccaccc aaatttcatt
    51061 ttttttcgtt tgcatgaact caattcccaa acatcaatgc ggtcagcaca aaatccagcc
    51121 ccagaacagc cagagacgag tggacaacgg tgcgagtggt tgcccggcta atcccggcag
    51181 acgtcgggat ggcgtcgtag ccgttaaaca acgaaatcca cgtcaccgtg atggcgaaca
    51241 ccacgctctt aatcagacag ttgaccagat ccatacgcca gtcgacggca ttttgcattg
    51301 ccgaccagaa gaacccgcta tcaatgcctt tccaactgac gccgaccaga gatccgcccc
    51361 agatccccac ggcgacgaaa ataaccgtca acagtggtaa tgaaataacc ccagcccaga
    51421 aacggggaga aataacccga cgcagcggat ccaccgccat catctccata ctggagagtt
    51481 gctctgtagc gcgcatcagg ccgatttctg cggttagcgc cgaaccagca cgcccggcaa
    51541 acaacaacgc ggcaaccacc ggccccagtt cacgcagtag cgataacgcc accagcatac
    51601 ccagactggt ttccgcacta taagtggtca gaaccagata accttgcagc cccaacacca
    51661 ttccgatgaa cacgccagaa accacaataa tcagcatcga caggacgccg acattataga
    51721 gctggcgcac cagcagcggc gcatgtttgc gaaattccgg tttgccgacc agcgcattga
    51781 ataacattaa cccggcccgc ccgaacgttc tcagggtttt aatcccttta tgtccgagcg
    51841 acgccagcgc atttaacagc atgagtggct taactccctg gtaaaagatc agcgtgataa
    51901 tcgccggcag gatagcggaa cggaacaggc ccgtcagcta tcccgtccag aaactgacgt
    51961 acgcgcggat caggattcgc ctgcaacgcc tgggcactgc catgagcgac aatttttttg
    52021 tccgccagga tccaggcgtg atccgcaata cttaacactt ccggcacatc gtgagaaacc
    52081 accacacaag tcacgcccag cgcgctgttc agctcagaaa tcagcttcac cagtacgccc
    52141 atggtgatgg gatcttgccc aacaaaaggt tcatcaaaca tgatgagatc cggctccagc
    52201 gcaatcgcac gcgccagcgc tgcacgccgc gccatcccac cggaaagttc agaaggcatt
    52261 agtttagccg ctccacgcag ccccacggcc tccagcttca tcatcaccgt actatgcaac
    52321 aatggcgcgg gaagttgggt atgttcgcgc agtggatagg cgacgttgtc aaatacgttc
    52381 atatcagtga acaacgcccc ggactgaaat aacatgctca tccgtttgcg cactgtatac
    52441 aggcgcgaac gagacatcgc cggaatattc tcaccatcga aaaggatctc accatgatct
    52501 ggtgcgattt gcccgccaat cagacggagt agcgtcgttt taccgatgcc cgatggcccc
    52561 atgatcgccg tgatcttccc tcgcggcacg gtcagggaaa tattatcgaa gatgcagcga
    52621 ttgccacgcg taaaactgac atcgcgcata tcgactaaat tcgccacaga ctgctccata
    52681 attcaccctt cgtcttgcgt tgattttcta agcatggcgc tcaatttaac cttgaaccca
    52741 acatatttac agaatattac ccgccgtggt tagcgaaagc tggcatttgt tttacttttt
    52801 agccgcataa agtcaaaatt aagcatccgt tacggctttc tgaaaatctt cagcggaccg
    52861 gcgagtatac ctgaagaaag gacgttagat gcttttagct acggcactgt taattgttgg
    52921 tttacttttg gtcgtttaca gtgccgaccg cctggttttt gccgcgtcta ttctttgccg
    52981 aacctttggc atcccgccgc tgatcatcgg catgacggtg gtcagtattg gtacatcgtt
    53041 accagaagtc atcgtctcgc ttgccgcgtc tctgcacgaa caacgcgatt tagccgttgg
    53101 tacagccctc ggctcaaaca ttatcaatat attgctgatc ctcggtctgg ctgcgctggt
    53161 tcgtcctttt accgtccatt ctgatgttct acgccgtgaa ttacccttaa tgttgttggt
    53221 cagcgtggtg gccggttccg tactctatga cggacaactt agtcgcagcg atggtatctt
    53281 tctcctcttt ctggctgtgc tatggctgct gttcattgtt aaacttgcac gtcaggctga
    53341 acgtcagggg actgacagcc tgaccagaga gcagcttgca gagctgccgc gtgacggcgg
    53401 attgcccgtc gcgtttttat ggctcggcat tgcgcttatc atcatgccag tggccacgcg
    53461 gatggtggtt gataacgcca cggtgctggc gaattacttt gccatcagcg agttgacgat
    53521 gggtctgacg gcaattgcta tcggaaccag cctgccggaa ctggcaaccg caatagcggg
    53581 ggttcgcaaa ggtgaaaacg acattgctgt cggaaatatc attggcgcaa acatttttaa
    53641 tattgtcatc gtgttgggtt tacccgcgct gataacgcca ggagagattg atccactggc
    53701 gtacagtcgt gactacagcg tgatgttgct ggtgagcatt atttttgcgt tgctgtgctg
    53761 gcggcgctcc ccgcaaccgg gccgtggtgt aggggtatta ttaactggcg gatttatcgt
    53821 atggctggcg atgttgtact ggttatcgcc aatactcgtt gaataactgg aaacgcatta
    53881 tgtcgcacgt agagttacaa ccgggttttg actttcagca agcaggtaaa gaagtcctgg
    53941 cgattgaacg tgaatgcctg gcggagcttg atcaatacat caatcagaat ttcacgcttg
    54001 cctgtgaaaa gatgttctgg tgtaaaggga aagttgtcgt catggggatg ggaaaatcgg
    54061 ggcatattgg gcgaaaaatg gcggcaacgt ttgccagcac cggtacacct tcatttttcg
    54121 tccatcctgg tgaagccgcg catggtgatt taggcatggt taccccacag gatgtggtga
    54181 ttgctatctc taactctggt gaatccagcg aaatcacggc cttaattcca gtgcttaagc
    54241 gtcttcacgt accgttaatc tgcatcaccg gtcgcccgga gagcagcatg gcgcgcgccg
    54301 cagatgtgca tctgtgtgtt aaagtagcga aagaagcctg tccgttaggg ctggcaccga
    54361 ccagcagcac caccgccacg ctggttatgg gcgatgccct cgctgtcgcg ctgttaaaag
    54421 cacgcggctt tactgctgaa gattttgcgc tctcacaccc aggcggcgca ctgggtcgta
    54481 aacttctgct gcgcgtaaac gatattatgc atacgggcga tgagatcccg catgttaaga
    54541 aaacggccag tctgcgtgac gcgttgctgg aagttacccg caaaaatctt ggtatgactg
    54601 tcatttgcga tgacaatatg atgattgaag gcatctttac cgacggtgat ttacgccgtg
    54661 tcttcgatat gggcgtggat gttcgtcagt taagtattgc cgatgtgatg acgccggggg
    54721 gaatacgtgt gcgccctggc attctggccg ttgaggcact gaacttaatg cagtcccgcc
    54781 atatcacctc cgtgatggtt gccgatggcg accatttact cggtgtgtta catatgcatg
    54841 atttactgcg tgcaggcgta gtgtaaagat tcaaggataa acaacaatga gcaaagcagg
    54901 tgcgtcgctt gcgacctgtt acggccctgt cagcgccgac gttatagcaa aagcagagaa
    54961 cattcgtctg ctgatcctcg atgtcgatgg cgtactgtca gatggcctga tttatatggg
    55021 caataatggc gaagagctga aagcgttcaa tgttcgtgac ggttatggca ttcgttgtgc
    55081 gctcacctct gatattgaag tcgctatcat taccgggcga aaggctaaac tggtagaaga
    55141 tcgttgtgcc acattgggga tcactcactt gtatcagggg cagtcaaaca aactgatcgc
    55201 ctttagcgat ctgctggaaa aactggcgat tgccccggaa aatgtggctt atgtcggcga
    55261 tgatctcatc gactggccgg taatggaaaa agtgggttta agcgtcgccg tggccgatgc
    55321 gcatccactg ttgatcccgc gcgccgatta cgtgacgcgc attgctggcg gtcgtggcgc
    55381 agtgcgcgaa gtttgcgact tattactcct ggcgcagggc aaactggatg aagccaaagg
    55441 gcaatcgata tgagtaaagc cagacgttgg gttatcattg tgctatcact ggcggttctg
    55501 gtgatgatcg gcattaatat ggccgaaaaa gacgataccg cccaggtggt cgtcaacaac
    55561 aatgatccca cctataaaag cgagcatacg gacacgctcg tctataaccc agaaggggca
    55621 ctaagctatc gattgattgc tcaacacgtt gaatattatt ccgatcaggc cgtttcgtgg
    55681 tttacgcagc cggtacttac cacgtttgat aaggataaaa tcccgacatg gtccgtaaaa
    55741 gcagataaag ccaagctgac caatgaccgg atgctctatt tatatggaca cgttgaagtc
    55801 aacgcacttg tgccagactc tcaacttcgc agaatcacga cggataacgc gcagatcaat
    55861 ctggtgacgc aggatgttac ctctgaagac ctcgtcacgt tatacggaac aacatttaac
    55921 tccagcggtc tgaaaatgcg cggcaactta cgcagcaaga acgccgagct gattgaaaag
    55981 gttagaacat cctatgaaat tcaaaacaaa caaactcagc cttaatcttg tgcttgccag
    56041 ctcacttctg gccgccagca ttccggcatt tgccgtaacc ggagacactg atcagccgat
    56101 ccacattgaa tcggaccagc aatctcttga tatgcaaggc aacgtggtta cctttaccgg
    56161 taatgtcatc gtcacccagg gcaccatcaa aattaatgcc gacaaagtgg tcgttacccg
    56221 tccgggcggc gaacaaggta aagaagtgat tgacggctac ggtaaaccgg caacgttcta
    56281 ccagatgcag gacaacggta aacccgttga aggtcacgct tcccagatgc actacgaact
    56341 ggcaaaagat tttgtcgttc tgacgggtaa tgcttatctg cagcaggtcg atagcaacat
    56401 taagggcgat aagatcactt acctggtgaa agagcagaaa atgcaggctt tcagcgacaa
    56461 aggcaagcgc gtaacaaccg ttctggtgcc gtcgcagctg caggacaaaa acaacaaagg
    56521 ccagaccccg gcacagaaga agggtaatta attcgttatg gcaacattaa ctgcaaagaa
    56581 ccttgcaaaa gcctataaag gccgtcgcgt ggtagaagac gtcagcctga ccgtcaactc
    56641 cggggaaatt gtcggtctgc tggggccaaa cggtgccggt aagaccacca ctttctacat
    56701 ggttgtaggc attgtgccgc gcgatgcggg caacatcatt attgatgatg acgatatcag
    56761 tctgctgcct ctgcatgcac gcgcgcgccg cggtatcggc tatctgccac aggaagcctc
    56821 cattttccgt cgcctcagcg tttacgataa cctgatggcg gtactgcaaa ttcgtgacga
    56881 cttgtctgct gaacaacgtg aagaccgcgc gaacgagctg atggaagagt ttcacattga
    56941 gcacctgcgt gacagcatgg ggcagtcact ctccgggggt gaacgtcgcc gtgtagaaat
    57001 tgcccgcgca ctggctgcga atccgaaatt tattctgctc gacgaaccgt ttgccggggt
    57061 tgacccgatc tcggttatcg acattaaacg catcattgag cacctgcgcg acagcggcct
    57121 gggcgtgctg atcactgacc acaacgtgcg tgaaacactg gcggtttgtg aacgcgctta
    57181 tatcgtcagt caggggcatt tgatcgccca cggcacgcct acagaaatct tacaagacga
    57241 acacgttaag cgtgtatacc ttggggaaga cttcagactc tgatagggta gaagtttgcg
    57301 acgttttagc aggagagtac gattctgaac atgaagcaag gtttgcaact caggcttagc
    57361 caacaactgg cgatgacgcc acagctccaa caggcaattc gtctgttgca gttgtcgacg
    57421 ctggaacttc agcaggagct acagcaggcg ctggagagta atccgctgct tgagcaaatc
    57481 gacactcatg aagaaatcga cacccgcgaa acgcaagaca gtgaaacgct ggacaccgcc
    57541 gacgcgctcg aacaaaaaga gatgccggaa gagctgccgc tcgatgccag ttgggacacc
    57601 atttacaccg ctggtacacc atccggcacc agcggtgact acattgacga cgagctgccg
    57661 gtctaccagg gcgaaacgac gcagaccttg caggattacc tgatgtggca ggttgagctg
    57721 acaccgtttt ccgacactga ccgcgctatt gctacctcta tcgtcgatgc cgttgatgaa
    57781 accggttatc tgactgtccc gctggaagat attctcgaaa gtataggcga tgaagagatc
    57841 gacatcgacg aagttgaagc cgtccttaag cggatccaac ggtttgatcc ggtcggtgtg
    57901 gcggcaaaag atctgcgtga ctgtctgctg atccaactct cccaattcga taagaccacg
    57961 ccgtggctgg aagaggccag actgatcatt agcgatcatc tcgatctgtt agccaatcac
    58021 gacttccgca ctttaatgcg cgtcacgcgt ctgaaagaag atgtgctgaa agaagccgtc
    58081 aatctgatcc agtcgctcga tccgcgcccc gggcagtcga tccagactgg cgaacctgag
    58141 tatgtcattc cagatgtgct ggtgcgtaag cataacggtc actggacggt agaactcaac
    58201 agtgacagca ttccgcgtct gcaaatcaac cagcactacg cctcgatgtg caataacgcg
    58261 cgcaacgatg gtgacagcca gtttatccgc agcaatctgc aggatgccaa atggttgatc
    58321 aagagtctgg aaagccgtaa cgatacgcta ctgcgcgtga gtcgctgtat cgttgaacag
    58381 cagcaagcct tctttgagca aggtgaagaa tatatgaaac cgatggtact ggccgatatc
    58441 gcccaggctg tcgaaatgca tgaatcgacg atatctcgcg tgaccacgca aaaatacctg
    58501 catagtccac gaggcatttt tgaactgaag tatttctttt ccagtcacgt caataccgag
    58561 ggcggcggcg aagcttcctc cacggcgatt cgtgcgctgg tgaagaaatt aatcgcggcg
    58621 gaaaacccag cgaaaccgtt gagcgacagc aagttaacct ctttgctgtc ggaacaaggt
    58681 atcatggtgg cacgccgcac tgttgcgaag taccgagagt ctttatccat tccgccgtca
    58741 aaccagcgta aacaactcgt ttgacccaac cgataaggaa gacactatgc agctcaacat
    58801 taccggaaat aacgtcgaga tcaccgaggc actgcgcgaa tttgttacag ccaaatttgc
    58861 caaacttgag caatattttg accgaatcaa ccaggtctat gttgttctga aagtggagaa
    58921 agtcacccac acctcagatg caacactgca tgtaaacggt ggtgaaattc atgccagcgc
    58981 ggaaggtcag gacatgtacg ctgccattga tggcttaatt gataagctgg cacgccagtt
    59041 gaccaaacat aaagataaac tgaaacaaca ctaattgtcc gggcaattag catgtgcatg
    59101 gcggtctgtt gtgcggcaca acgggccatt tgtacggtta atgctccgag cctgttccac
    59161 tgtttgagtg ggcaggttct taggtgaaat tatgacaaat aatgatacaa ctctacagct
    59221 tagcagtgtt cttaacaggg aatgtacgcg aagccgcgtc cactgtcaga gcaaaaaacg
    59281 cgccctggaa atcatcagcg agctggcggc gaaacaactt agcctgccgc ctcaggtggt
    59341 ttttgaagct atcctgacgc gggaaaaaat gggcagtacc ggtatcggca atggtattgc
    59401 cattccgcat ggcaaactgg aagaagatac tctgcgcgcc gttggcgttt tcgttcagct
    59461 cgaaacgcct atagctttcg atgccatcga caaccaaccg gtggacttac tttttgccct
    59521 gctggtgccg gcagaccaaa ctaaaacgca cctgcatact ctgtcgctgg tggcgaaacg
    59581 tctggcggac aaaaccatct gccgccgttt acgcgcagcc cagagcgatg aagagctgta
    59641 tcaaatcatt acggataccg aaggtactcc ggatgaagcg tagttattcg gtaatgtctc
    59701 ttttagacgt tgtgaggaga aacagtacat ggtactgatg atcgtcagcg gacgttcagg
    59761 ttcaggtaaa tctgtcgccc tgcgtgcgct ggaagatatg ggtttttact gcgtggataa
    59821 ccttcccgta gtgttgttac ccgatctggc tcgaaccctg gccgatcgcg agatttctgc
    59881 cgccgtcagc attgatgttc gtaatatgcc ggagtcacca gaaatattcg aacaggcgat
    59941 gagtaacctg cctgacgctt tctcaccgca actcctgttc ctggatgccg accgtaatac
    60001 cttaattcgt cgttacagtg acacgcgccg actgcatccg ctttccagca aaaacctgtc
    60061 gctggaaagt gctatcgaca aagaaagcga tttgctggag cctctgcgtt cgcgagcgga
    60121 tctgattgtc gatacctcag aaatgtccgt tcacgagctg gctgaaatgc tgcgtacccg
    60181 tctgctgggt aaacgtgaac gcgaactgac catggtcttt gagtctttcg gcttcaaaca
    60241 cggtatccct atcgatgcag attacgtctt tgacgtgcgc ttcttgccga acccgcactg
    60301 ggatccgaaa ctgcgtccaa tgacaggtct tgataaacct gtcgccgcgt tcctcgaccg
    60361 ccacacagaa gtacacaatt ttatctacca gacgcgaagc tatcttgagc tatggttacc
    60421 tatgctggaa accaacaacc gtagctactt gacggtcgcc attggttgta ccggcgggaa
    60481 gcaccgttcg gtgtatattg cagagcaact ggcagactac ttccgctcgc gcggtaaaaa
    60541 cgtccagtca cgccatcgta cgctggaaaa acgtaaacca tgaccgtcaa gcaaactgtt
    60601 gaaatcacaa acaagctggg catgcatgcc cggcctgcaa tgaagctgtt tgaattaatg
    60661 cagggttttg acgctgaagt gctcttacgt aatgacgaag gcaccgaggc tgaagccaac
    60721 agcgttattg cgctgctgat gttggattct gccaaaggac ggcagattga agttgaagcg
    60781 accggtccac aggaagagga agcactggcc gccgttatcg ccctctttaa ttctggtttt
    60841 gatgaagatt aatcttcatc actttgacat acaactccct tcaaactccc cccgacaata
    60901 agaaaatcac gtactgaaat cgttctcaat caacgtcatt tgtacatttt gtgcgctttt
    60961 cactttcaga agaaccttaa gaaaacctta agaggcattg tttaggtttt gtttaagtta
    61021 atcgaccata ctggagatcg tcagaaaata tttccaggag atggcatgat tcgcttatct
    61081 gaacaaagtc ccctgggcac cggaagacat cggaaatgtt atgcgcatcc ggaagatgcc
    61141 caacgctgta tcaagattgt ctaccatcgt ggcgatggtg gcgataaaga gatccgccgt
    61201 gagttaaagt actacgcgca tcttggtcgc cggttaaaag actggagtgg aataccgcgc
    61261 tatcacggta ccgttgagac ggattgcgga accggttatg tctacgatgt gattgcagat
    61321 tttgacggca agccttccat tacgctgacc gaatttgctg aacaatgccg ttacgaagaa
    61381 gacattgcac aactgcgcca gctactgaaa cagctgaagc gttatttgca ggataaccgt
    61441 atcgtgacga tgtcgctgaa gccgcagaat atcctctgtc accgcatcag tgagtcagag
    61501 gttatcccgg tcgtctgcga caacattggt gaaagcacat tgattccact ggcgacctgg
    61561 tcgaagtggt gttgtctgcg taagcaagag cggttatgga aacgatttat cgcccaaccg
    61621 gcgctggcta ttgccctgca gaaagatctg caacctcgtg agagcaaaac gctggccctc
    61681 acttcgcgcg aagcttaatc cagctggtgt tgttgcataa acggctcacc gcctaactga
    61741 tacatctgcc gtaaaatcca cgcctgacgg ctacgcacgt agcccgatgg cgaggagact
    61801 ttgaaacgaa gtggattagg taatacagct gccagtaatg cagcttccga ccgggtaagt
    61861 ttgctcgcgg gtttgtggaa ataacgttgt gccgcagctt cgacgccaaa cacaccgtcg
    61921 ccaaattcgg cgatattcag gtaaaccgtc aggatacgct ttttgctcca gaccgtttct
    61981 atccccagcg ttaatccggc ttccagccct tttcgaaccc agctacgccc atcccataaa
    62041 aagagatttt tggctgtctg ttgagaaatc gttgaagcac cgcgaatacg gttttcattg
    62101 cgctcgttgt gcgccagggc tttctcaatg gaagcgacat caaagcccca gtgctcagga
    62161 aatttctgat cttctgcggc aatcaccgcc agtcccatcc acggcgagat ttgatccata
    62221 ctgacccagt cagaatgtgc cacgtaacga aaattgccat gcagccaggc gctgacctgt
    62281 cgctcgacca ttaccgctga gaagggaaca ggcgcaacgc taaacaacgc gatgcccccg
    62341 ccccagaaaa cggcgaggac aaccattaac cgcaaaagaa aacggcgaac gaaactaaac
    62401 accgttaagc ggcttttact cattcagcca gaaccagcac gcgggaaacc agcttatcaa
    62461 tgccgctcgc cgcttctgca atgttctgcg ccagcatata tgctggggtg gtgacaatct
    62521 tattgtcttc atcaaccacg atatcatcga caggacacgg cacatgctcc gcgcccatct
    62581 cttccagcac ttctgcggta tcgatatcag taccgatggt caaacgcagc gggaaatcga
    62641 aaattttcgg cagcatcgcc ggggcaatac acataaaacc aagcggtttt ccggcctgat
    62701 gcatcgcttg tgccagcgcc tttaattcac ggtcaacggt gcattcgcta ccaagactgg
    62761 caaaattgct taaattcttc gccgcgccaa acccccccgg cacaatcaac gcatccagtt
    62821 cagcggcatc ggcctgggcc agaggacgga tttcaccgcg cgttattcgt gccgcttcaa
    62881 tcagcacatt gcgcgtttcc gtcatcgctt cgccagttaa atggttgata acatcaacct
    62941 gctgcttatc cggtgcaaag cagaccgcct gcgcaccgct gcgtgaaata gctaacaacg
    63001 tcaacaccgc ttcatgaatt tcagaaccgt catagacgcc gcatccgctc agaattacgc
    63061 caattttctt cattgtgatc atcctttcgc aattgactga aacacattaa tttttttaat
    63121 aaaaatggta cgcatcacac atttaactga ttcatgtaac aaatcattta agttttgcta
    63181 tcttaactgc gtgcggcctg aaaaacagtg ctgtgccctt gtaactcatc ataataattt
    63241 acggcgcagc caagatttcc ctggtgttgg cgcagtattc gcgcaccccg gtctagccgg
    63301 ggtcattttt tagtggcttt tgccacccac gctttcagca cttctacgtc gtgacgccac
    63361 tcttctttca tctcttcaat ccattcaccg acgttatctt cccaggccgg aaggtcagga
    63421 gactgaattt gctgacccag ctgttgcaga tggcgtaacc ccactgaccc cgccgcacct
    63481 ttaattttat gtccttcctc aacaatgcct tttttatcct gcgccgtcag attcgactcc
    63541 agcacgctga catagcccgg catcatcttc tcaaacaccg ctaacccgtc ggtgatcagc
    63601 ttcggtccta caagttcgag atactgttcc agcatgggaa tatcgagcaa tgcttctgat
    63661 ttactgttct cttctgtcgt caccgtactc tcctcatcat cctgggtatc ccagaatttc
    63721 ttgatcatcg cggttagcgc cggaacagaa agcggcttac tcagcacatc atccattcca
    63781 gcattgaggt actcttgttt gtctttcagc acgttagcgg ttaaggccac cagcggcggt
    63841 aaatcctcgc gcggataacg tttcgtcagt tcacgagaga tatccagccc ggtcatatct
    63901 ggcaactgaa tatccagcaa caccaggtcg tattcgcccg gtttaaacat ctccagcgcc
    63961 gccttgccgg tcatggcgac atcaacgctg ttacctaatt tttccagcac agaacgcgca
    64021 acaatcacgt tcagttcaat gtcttccacc agcagcacat tcagcgccgg taaaggcata
    64081 tcgtcttcat caaacgcatc atcgacctct tctgctaccg acggtgcgtg gatcgtcaac
    64141 gtaaaggttg aacctttgcc ctgttcgctg gtaaccgtaa tatcgccgcc catatttttc
    64201 gccagacgac gagaaacggc cagaccaata ccggtgccgg tggcaggttt accgccatga
    64261 ctgtctttca cctggtaata catggcgaaa attttatcca gctcatcctg cggaatgccg
    64321 ataccagagt cttccacttc aaaatgcagc atatcgcctt catcgtagcg cacgcgcacg
    64381 gtaacctggc cttgctgggt gaatttgacg gcgttactga tgaggttcca caggatctgc
    64441 cgtaaacgcg tcccgtcggt aatgacctga tgcggtaatg gcagcgtcgg ctccaggtta
    64501 aagcgcaatc ctttttgttg cgcctgcaat gcggagagat tttccagatc ggcaaggaag
    64561 ctggtgaaat caaccggttg attatcaagc tggaccttgc gccgttccat cttatccatg
    64621 tcgataatat cgttaaagat attccccagc gtgacggccg aaacatggat ggtcttgaga
    64681 tatttttcct gctcggcggt gagttcggta tccagcagaa tgcggctcag accgacgata
    64741 ccgttcagcg gtgtacgcaa ttcgtgactg atggtggaga taaacgtcgt tttgtcgcgg
    64801 ctggcccgtt caagcgcatc ctgataccgc ttacgctcgg taatgtcgcg accaaagccc
    64861 atcaaaccgt gacgtttacc cacgcggtcg tagtacggca ctttacggat ttcaaagcag
    64921 gctttgcgcc cgtccgggta atccagccac tgttcatagg tcagtgacac attatgacgg
    64981 aacacttttt catcggtttc aatgactttt gcggcggctt ccggtgagta aacatcagca
    65041 ggtttcaggt gaaccagttg tttttcgctt tttccggtca gcagctccat cgcgcggtta
    65101 cagccggaaa actctttatc ttcgttacga taaaaaacca ggtcgggtga agcatcaagg
    65161 aaggaacgta agaatgagga ttgctgctcg agctgaattt gtgtctcttc gcgctctttg
    65221 atttcaattt tcagttggcc gaaggtttcc tgcagttctg cttccgcttt ttcacgaacg
    65281 gcaatttcct gatttagctg ggcaatatta tcttttaact gaacgttgag gctcaaatcg
    65341 cgctcgcgca tctcctccag tttttgcacc agccgtgaca gacgttgtcg tgactcctcc
    65401 agttgctcga cgaccaccga tagaaagtag accgcccacg gcgtaatcag caaaccaaag
    65461 aagatagaac gaataacatc aatgctttcg acctgaccat gcagcaccat ggttaccgcc
    65521 atttgtacca caatggcaag aacgacgagg gccagcgcca gcaacattga gaagcgcacc
    65581 agacctaact tcatcatcag gtcaacataa tactgcgcca gcagacgaat ttgcttcatt
    65641 agggaattcc ttcacgacaa cctgccccaa taatacccaa ttctgacagt tacgttataa
    65701 attgtgtgag aaatgcggaa ttcccctcaa cgacctactc cgttggaggt agccacggac
    65761 gtcccagcgc cgatccctgt acgccatgtt cattcagata gcgatccagc tcgaccattc
    65821 ccgtccatcg attttcgcac cacagcggag caagcagcgt cgggcgacgg gcgctggcgg
    65881 aaatgcggtg gtagatcact tccggtggcg tatggcgaat catttctccg gcagtgagcg
    65941 tgtaatcctc cagttcaata ccgttcaaac gccccgcttc ccaggctttc gccataatgc
    66001 tgcctttcac aatatgcagc ggatgcagct ttatgccgtc cacgccggtt tcaaccactc
    66061 gctccagcgt ttgcaaacat tcagcctgcc cttcgccagg caggccgaca attaagtggg
    66121 aacacacctt cagcccgcgc tgacgtgcca gctgggttgt acgctgataa caggcaaaat
    66181 catggccgcg gttgatgcga tgcagtgttt tgtcgtgggc ggtttgtagc cccagctcca
    66241 gccacacttc gtaaccctgg tccttatatt cgcaaagcag atccagcacc gcatccggca
    66301 cgcagtccgg gcgggtaccc acacacaaac cgacaatatt ggcctggctc accgcctgct
    66361 gatacataga acgcagcacc tgaacttccg caaaggtgct ggtatacgcc tgaaagtagg
    66421 ccagatagcg tttagcgcgg ttaactaaat tcgcctggtg cgccagttgc tcggcaatgg
    66481 aacgatgctg ctgcgcttca tcggcaaacg aggcaacatt acagaatgtg cagccaccac
    66541 gcccgatggt accgtcacgg ttagggcagc taaaaccgcc gtgcagcgtc agcttatgca
    66601 ccttttgccc ataacgacgg gtgagatcac caccaaacat attgactaat ttctgtaact
    66661 gcataatctg atagaccgcg ccttgaaaag aggccaaagc ctgccatttt tagctcaatt
    66721 cggcgatgac ctggatcaat cgtcccggcc tgcttttatc aactgcataa tcaatcaaaa
    66781 ttaccgaaat ttcatgcata atcacataaa tcacttttgc ttatcttgtg tcagattttt
    66841 ttatctcctg atggatttta ggcaaaaaca gtagcatgaa acgtcattac caattaaggc
    66901 agtataaaat gctggttttg tcgtcagttc aaggcaggat aagggttaac acacctttat
    66961 gacagtcagg aattgactgt ttctctaacg acttcccttt tagccttaaa gataaaatcc
    67021 attttaattt cagtcattta ataaagaatt ttgcgctaaa gcacatttct gtaccaataa
    67081 gcttgccatt tgacctgtat cagctttccc gataagttgg aaatccgctg gaagctttct
    67141 ggatgagcag cctgctcatc atatttatgc agtaattgag atcccctctt caccgtatta
    67201 accgatgcga aaaggacaac aagggggcga atgcgaggcg cgcgtatgac acgcaaaccc
    67261 cgtcgccacg ctctttctgt gcccgtgcgc agcggttcgg aagtggggtt cccgcagagc
    67321 ctgggggagg ttcacgatat gttgtacgat aaatcccttg agagggataa ctgtggtttc
    67381 ggcctgatcg cccacataga aggcgaacct agccacaagg tagtgcgtac tgcaatacac
    67441 gcactggccc gcatgcagca ccgtggcgcg attctcgccg atggtaaaac cggcgacggt
    67501 tgcggcttgc tgttacaaaa accggatcgc ttttttcgca tcgttgcgca ggagcgcggc
    67561 tggcgtttag caaaaaacta cgctgtcggg atgctcttcc tgaataaaga tcctgaactc
    67621 gccgctgccg cacgccgcat cgttgaagaa gaactgcaac gcgaaacctt gtcgattgtg
    67681 ggctggcgtg atgtccccac taacgaaggc gtgctgggtg aaatcgccct ctcctctctg
    67741 ccacgcattg agcaaatttt tgtgaacgcc ccggcaggct ggcgtccacg cgatatggag
    67801 cgccgtctgt ttatcgcccg ccgccgcatt gaaaagcgtc tcgaagccga caaagacttc
    67861 tacgtctgta gcctgtcgaa tctggtgaac atctataaag gtctgtgtat gccgacggat
    67921 ctgccgcgct tttatctgga tcttgcggac ctgcgtctgg aatcggccat ttgcctgttc
    67981 caccagcgct tctccactaa caccgtaccg cgctggccgc tggcgcaacc gttccgctat
    68041 ctggcgcata acggtgaaat caacaccatc accggtaacc gccaatgggc gcgtgcgcgt
    68101 acttataaat tccagacacc gcttatccct gacctgcacg acgccgcacc gttcgtcaac
    68161 gaaaccggct ctgactccag ttcgatggat aacatgctgg aactgctgct ggcaggcggg
    68221 atggatatca tccgcgccat gcgtctatta gtaccacccg cctggcagaa caacccggat
    68281 atggacccgg aactgcgtgc cttctttgac tttaactcca tgcatatgga gccgtgggat
    68341 ggcccggcgg gcatcgtgat gtccgacggt cgttttgccg cctgtaacct cgaccgtaac
    68401 ggtctgcgtc cggcgcgcta cgtcatcacc aaagataagc tcatcacctg cgcctctgaa
    68461 gtcggtatct gggattacca gcctgacgaa gtggtcgaaa aaggccgcgt cgggccaggc
    68521 gaactgatgg ttatcgacac ccgcagtggg cgtattctgc actcggcaga aaccgatgac
    68581 gatctgaaaa gccgccatcc atataaagag tggatggaga aaaacgtccg ccgactggta
    68641 ccgtttgaag atctgcccga tgaagaagtg ggtagccgcg aactggacga cgacacgctt
    68701 gccagctacc agaaacagtt taactacagc gcggaagagc tggactccgt aattcgcgta
    68761 ctgggcgaaa acggtcagga agcggtcggt tcgatgggcg atgatacccc attcgccgtg
    68821 ctctccagtc agccgcgcat tatttacgac tacttccgcc agcagtttgc ccaggtgact
    68881 aacccgccaa tcgacccgct gcgtgaagcg catgttatgt cgctcgccac cagtatcggt
    68941 cgtgaaatga acgtcttttg cgaagcagag ggccaggcgc accgtttaag ctttaaatcg
    69001 ccgattctgc tctactccga tttcaaacag ctcacgacga tgaaagagga gcactaccgc
    69061 gcagatacgc tggatatcac ctttgacgtc actaaaacca cgctcgaagc gacagtcaaa
    69121 gagctgtgcg acaaagccga aaaaatggta cgtagcggca ccgtgctgct ggtgctctcc
    69181 gaccggaata tcgctaaaga tcgcctgccg gttccagccc cgatggcggt tggcgcgatc
    69241 cagacccgtc tggtcgatca aagcctgcgt tgcgatgcca acatcatcgt cgaaaccgcc
    69301 agcgcccgcg atccgcacca cttcgccgtg ttgctgggct tcggcgcgac ggctatttat
    69361 ccataccttg cctatgaaac gctgggccgc ctggtagaca cccatgcgat tgccaaagat
    69421 tatcgtaccg tgatgctcaa ctaccgtaac ggcatcaaca aaggcttgta caaaatcatg
    69481 tccaaaatgg gcatctccac catcgcctct taccgctgct cgaaactgtt tgaagcggtc
    69541 ggtctacacg atgatgtagt gggcctgtgc ttccaggggg cggtcagccg cattggtgga
    69601 gcaagctttg aagacttcca gcaggatctg ctgaatctgt cgaaacgtgc ctggctggcg
    69661 cgtaagccca tcagccaggg cggtctgctg aaatacgtcc acggcggcga ataccacgcc
    69721 tacaacccgg acgtggtgcg cacgctgcaa caagcggtac aaagcggcga gtacagcgac
    69781 tatcaggaat acgcgaagct ggttaatgag cgtccggcaa ccacgctgcg cgatctgctg
    69841 gcaattacgc cgggtgaaaa cgcggtcaac attgctgatg ttgaaccggc aagcgaactg
    69901 tttaaacgct ttgataccgc cgcgatgtct atcggcgcgt taagcccgga agcccacgag
    69961 gcgctggcgg aagcgatgaa cagcatcggc ggtaattcga actccggtga aggcggcgaa
    70021 gacccggcgc gctacggcac caacaaagtg tcgcgcatca agcaggtggc ttccggtcgc
    70081 tttggggtta ctccggcgta tctggtcaat gccgacgtca ttcagattaa agtcgcccag
    70141 ggcgcgaagc caggcgaagg cggtcagttg ccgggtgata aagtcacgcc ttacatcgcc
    70201 aaactgcgct attcggtgcc cggagtgacg ctgatctccc cgccgccgca ccacgatatc
    70261 tactctatcg aggacttagc gcagctcatt ttcgacctca agcaggttaa cccgaaagcg
    70321 atgatctccg tgaagctggt ttccgaaccg ggagtaggca ccatcgcgac tggcgtggca
    70381 aaagcttatg cggacttgat caccatcgca ggctatgacg gcggcaccgg cgcaagtccg
    70441 ctttcatcgg tgaaatacgc aggctgtccg tgggagctgg ggcttgttga aacccagcag
    70501 gcgctggttg ctaacggctt gcgtcacaag atccgtttgc aggtcgatgg cggcctgaaa
    70561 acgggtgtcg atatcatcaa ggcggcgatt ctcggcgcag aaagcttcgg cttcggcact
    70621 ggcccgatgg tggcgctcgg ctgtaaatat ctacgtattt gccatctgaa caactgcgca
    70681 acgggtgtag caactcagga tgacaaactg cgtaagaacc actatcacgg cctgccattc
    70741 aaggtgacga attactttga gtttatcgcc cgtgaaaccc gcgagctgat ggcacagctt
    70801 ggcgtaacac gtctggtgga tctgattggt cgcaccgacc tgctgaaaga gctggacggt
    70861 ttcaccgcca aacagcagaa gctggcgctg tcgaagctgc tggagactgc cgaaccgcat
    70921 ccaggtaagg cactctactg caccgaaaac aacccgccgt ttgataacgg cctgctgaac
    70981 gcgcagttgc tgcaacaggc gaaaccgttt gtcgatgagc gccagagcaa aaccttctgg
    71041 ttcgatattc gcaacaccga ccgttctgtc ggcgcgtcgc tttcaggcta tatcgcccag
    71101 acgcacggcg atcaggggct ggcagccgat cctatcaaag cgtacttcaa cggcaccgca
    71161 ggccagagct tcggcgtgtg gaacgcgggc ggcgtggaac tgtacctgac cggtgatgcc
    71221 aacgactatg tcggtaaagg catggcgggc ggcttaatcg ccattcgtcc tccggttggt
    71281 tccgccttcc gcagccatga agcaagcatt atcggcaaca cctgcctgta tggcgcgacc
    71341 ggtggtcgtc tgtatgccgc aggccgcgcg ggtgaacgtt tcggcgtgcg taactccggt
    71401 gctatcaccg tggtagaagg cattggcgac aacggttgtg aatatatgac gggtggtatc
    71461 gtctgcattc tgggtaaaac cggcgttaac ttcggtgcgg gcatgaccgg cggtttcgct
    71521 tacgttctcg atgaaagcgg cgatttccgc aaacgcgtta acccggaact ggtcgaggtc
    71581 ttaagcgttg acgctctggc gatccatgaa gagcatctgc gtggtcttat caccgagcat
    71641 gtgcagcata ccggctctca gcgcggtgaa gagattctgg cgaactggtc aaccttcgcc
    71701 actaaatttg cgctggttaa accgaagtcc agtgatgtaa aagcactgct gggtcaccgt
    71761 agtcgtagcg cagctgagtt gcgcgtgcag gcgcagtaag gggtagcaac aatgagtcag
    71821 aatgtttatc aatttatcga cctgcagcgc gttgatccgc caaagaaacc gctgaagatc
    71881 cgcaaaattg agtttgttga aatttacgag ccgttttccg aaggccaggc caaagcgcag
    71941 gctgaccgct gcctgtcgtg cggcaaccca tactgcgagt ggaaatgccc ggtacacaac
    72001 tacatcccga actggctgaa gctcgccaac gaggggcgta tttttgaagc ggcggaactg
    72061 tcgcaccaga ccaacaccct gccggaagtt tgcggacgag tctgcccgca agaccgtctg
    72121 tgcgaaggtt cctgcactct gaacgatgag tttggcgcgg tgaccatcgg caacattgag
    72181 cgctatatca acgataaagc gttcgagatg ggctggcgtc cggatatgtc tggtgtgaaa
    72241 cagaccggta aaaaagtggc gattatcggc gcaggcccgg caggtctggc gtgtgcggat
    72301 gtcctgacgc gtaacggcgt aaaagccgtt gtcttcgacc gtcatccaga aattggcggg
    72361 ctgctgacct tcggtattcc ggccttcaag ctggaaaaag aggtaatgac gcgtcgccgt
    72421 gaaatcttca ccggcatggg tattgaattc aaactcaata ccgaagtggg ccgcgacgta
    72481 cagctggacg atctgctgag tgattacgat gccgtgttcc ttggcgtcgg gacttatcag
    72541 tcaatgcgcg gcgggctgga aaacgaagac gccgatggcg tgtacgcagc gctgccgttc
    72601 ctcatcgcca acaccaaaca gttaatgggc tttggtgaaa cccgcgacga accgttcgtc
    72661 agcatggaag gcaaacgcgt ggtggtcctt ggcggtggcg acactgcgat ggactgcgtg
    72721 cgtacgtccg tgcgccaggg agcgaagcac gttacctgtg cctatcgtcg tgatgaagag
    72781 aacatgccgg gttcccgccg cgaagtgaaa aacgcgcggg aagaaggcgt agagttcaaa
    72841 ttcaacgtcc agccgctggg tattgaagtg aacggtaacg gcaaagtcag cggcgtaaaa
    72901 atggtgcgta ccgaaatggg cgaaccggac gccaaaggcc gtcgccgcgc ggagatcgtt
    72961 gcaggttccg aacatatcgt tccggcagat gcggtgatca tggcgtttgg tttccgtcca
    73021 cacaacatgg aatggctggc aaaacacagc gtcgagctgg attcacaagg ccgcatcatc
    73081 gccccggaag gcagcgacaa cgccttccag accagcaacc cgaaaatctt tgctggcggc
    73141 gatatcgtcc gtggttccga tctggtggtg accgctattg ccgaaggtcg taaggcggca
    73201 gacggtatta tgaactggct ggaagtttaa gcgaggtaac aatgaattcg ccagactgtg
    73261 tctggcgaat caaattactg acgaagtgcg cgttgttttc tggcaaatgc ggcatgagcg
    73321 tttgaccttt cctataatag ggataatttt caataaattg tgctttgttc accaagtctg
    73381 atgagtgaag cacatcaagc aatttctcat ttacaatccg tctcaattac ttgttaacac
    73441 ctctgacaat accgattctg caagctattc agtcttttca ttccatgtaa att
//
LOCUS       DAPHKZ010000007        72929 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.007, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000007 DAPHKZ010000000
VERSION     DAPHKZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 72929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72929
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.007"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            89..1321
                     /gene="dgcM"
                     /locus_tag="RH288_000457"
     CDS             89..1321
                     /gene="dgcM"
                     /locus_tag="RH288_000457"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415857.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcM"
                     /protein_id="HDV4029555.1"
                     /translation="MITHNFNTLDLLTSPVWIVSPFEEQLIYANSAAKLLMQDLTFSQ
                     LRTGPYSVSSQKELPKYLSDLQNQHDIIEILTVQRKEEETALSCRLVLRKLTETEPVI
                     IFEGIEAPATLGLKASRSANYQRKKQGFYARFFLTNSAPMLLIDPSRDGQIVDANLAA
                     LNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFVHKLADGSTRHVQ
                     TYAGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQM
                     QHLAIAQDYSLLLIDTDRFKHINDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGE
                     EFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHEGNESIDELFKRV
                     DDALYRAKNDGRNRVLAA"
     gene            complement(1342..1905)
                     /gene="smrA"
                     /locus_tag="RH288_000458"
     CDS             complement(1342..1905)
                     /gene="smrA"
                     /locus_tag="RH288_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HDV4029556.1"
                     /translation="MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQL
                     DNFLTTGFLDIIPLSQPLEFRREGLQHGVLDKLRSGKYPQQASLNLLRQPVEECRKMV
                     FSFIQQALADGLRNVLIIHGKGRDDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
                     SGACYVALRKTAQAKQENWERHAKRSR"
     gene            complement(2235..3143)
                     /locus_tag="RH288_000459"
     CDS             complement(2235..3143)
                     /locus_tag="RH288_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4029557.1"
                     /translation="MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELE
                     EGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELRAAQEDIRQRQGQLAGQINIGMG
                     ASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
                     FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQT
                     PQVGVVCETFSACISLVAKSDFLSILPEEMGCDPLHGQGLVMLPVSEILPKAAYYLIQ
                     RRDSRQTPLTASLITQFRRECGYLQS"
     gene            3319..4629
                     /gene="abgA"
                     /locus_tag="RH288_000460"
     CDS             3319..4629
                     /gene="abgA"
                     /locus_tag="RH288_000460"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgA"
                     /protein_id="HDV4029558.1"
                     /translation="MESLNQFVNSLAPKLSHWRRDFHHYAESGWVEFRTATLVAEELH
                     QLGYSLALGREVVNESSRMGLPDEFTLQREFERARQQGALAQWIAAFEGGFTGIVATL
                     DTGRPGPVMAFRVDMDALDLSEEQDVSHRPYRDGFASCNAGMMHACGHDGHTAIGLGL
                     AHTLKQFESGLHGVIKLIFQPAEEGTRGARAMVDAGVVDDVDYFTAVHIGTGVPAGTV
                     VCGSDNFMATTKFDAHFTGTAAHAGAKPEDGHNALLAAAQATLALHAIAPHSEGASRV
                     NVGVMQAGSGRNVVPASALLKVETRGASDVINQYVFDRAQQAIQGAATMYGVGVETRL
                     MGAATASSPSPQWVAWLQSQAAQVAGVNQAIERVEAPAGSEDATLMMARVQQHQGQAS
                     YVVFGTQLAAGHHNEKFDFDEQVLAIAVETLARTALNFPWTRGI"
     gene            4629..6074
                     /gene="abgB"
                     /locus_tag="RH288_000461"
     CDS             4629..6074
                     /gene="abgB"
                     /locus_tag="RH288_000461"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgB"
                     /protein_id="HDV4029559.1"
                     /translation="MQEIYRFIDDAIEADRQRYTDIADQIWDHPETRFEEFWSAEHLA
                     SALESAGFTVTRNVGNIPNAFIASFGQGKPVIALLGEYDALAGLSQQAGCAQPTSVTP
                     GENGHGCGHNLLGTAAFAAAIAVKKWLEQYGQGGTVRFYGCPGEEGGSGKTFMVREGV
                     FDDVDAALTWHPEAFAGMFNTRTLANIQASWRFKGIAAHAANSPHLGRSALDAVTLMT
                     TGTNFLNEHIIEKARVHYAITNSGGISPNVVQAQAEVLYLIRAPEMTDVQHIYDRVAK
                     IAEGAALMTETTVECRFDKACSSYLPNRTLENAMYQALSHFGTPEWNSEELAFAKQIQ
                     ATLTSNDRQNSLNNIAATGGENGKVFALRHRETVLANEVAPYAATDNVLAASTDVGDV
                     SWKLPVAQCFSPCFAVGTPLHTWQLVSQGRTSIAHKGMLLAAKTMAATTVNLFLDSGL
                     LQECQQEHQQVTDTQPYHCPIPKNVTPSPLK"
     gene            6111..7637
                     /gene="abgT"
                     /locus_tag="RH288_000462"
     CDS             6111..7637
                     /gene="abgT"
                     /locus_tag="RH288_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate transporter"
                     /protein_id="HDV4029560.1"
                     /translation="MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTT
                     AILSAFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALVLGAG
                     LAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPPMGALIFLAVG
                     RHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAAAFNPQMHVSVIDNWYFMA
                     SSVVVLTIVGGLITDKIIEPRLGQWQGNSDEKLQTLTESQRFGLRIAGVVSLLFIAAI
                     ALMVIPQNGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPH
                     LMIEPMKEMAGFIVMVFPLAQFVAMFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLA
                     LLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIADSSVLPLAPVSPF
                     VPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
                     "
     gene            7648..8163
                     /gene="ogt"
                     /locus_tag="RH288_000463"
     CDS             7648..8163
                     /gene="ogt"
                     /locus_tag="RH288_000463"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDV4029561.1"
                     /translation="MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDI
                     HYRKEGYERISATNPGGLSDKLREYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPC
                     GQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            8358..9110
                     /gene="fnr"
                     /locus_tag="RH288_000464"
     CDS             8358..9110
                     /gene="fnr"
                     /locus_tag="RH288_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HDV4029562.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENNDALAQLAGHTRNVA"
     gene            9262..10212
                     /gene="uspE"
                     /locus_tag="RH288_000465"
     CDS             9262..10212
                     /gene="uspE"
                     /locus_tag="RH288_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HDV4029563.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQ
                     EVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGI
                     SAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD"
     gene            complement(10262..10519)
                     /locus_tag="RH288_000466"
     CDS             complement(10262..10519)
                     /locus_tag="RH288_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HDV4029564.1"
                     /translation="MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIP
                     LSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ"
     gene            10763..11794
                     /gene="ynaI"
                     /locus_tag="RH288_000467"
     CDS             10763..11794
                     /gene="ynaI"
                     /locus_tag="RH288_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low conductance mechanosensitive channel YnaI"
                     /protein_id="HDV4029565.1"
                     /translation="MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHA
                     VQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFE
                     KQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAG
                     KDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPN
                     SLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLV
                     YFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMD
                     NITPPEQGR"
     gene            complement(11845..13458)
                     /gene="mppA"
                     /locus_tag="RH288_000468"
     CDS             complement(11845..13458)
                     /gene="mppA"
                     /locus_tag="RH288_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide ABC transporter
                     substrate-binding protein MppA"
                     /protein_id="HDV4029566.1"
                     /translation="MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNA
                     KWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
                     VDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPA
                     WHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLL
                     TSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIAPIYQYTNG
                     RLIKPWLKGYPINNPEDVAYSRTMYIVKH"
     gene            complement(13795..14694)
                     /gene="pgrR"
                     /locus_tag="RH288_000469"
     CDS             complement(13795..14694)
                     /gene="pgrR"
                     /locus_tag="RH288_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator PgrR"
                     /protein_id="HDV4029567.1"
                     /translation="MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEE
                     RLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDSAMASLSDLQNRPSGTIRITTVE
                     HAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
                     GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVR
                     MEGQLLLNTIDLIIDAAIDGHGLAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYY
                     PHRRHAGSAFSLFIDRLKYKGAV"
     gene            14832..15752
                     /locus_tag="RH288_000470"
     CDS             14832..15752
                     /locus_tag="RH288_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV4029568.1"
                     /translation="MMNNKVSFTNSNNPTISLSAVIYFPPKFDETRQYQAIVLSHPGG
                     GVKEQTAGTYAKKLAEKGFVTIAYDASYQGESGGEPRQLENPYIRTEDISAVIDYLTT
                     LSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSIFRNGWENNVKSID
                     ALPYVEAGSNARTSDISSGEYAIMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPG
                     YATLRSLNQIITYDAYHMAEVYLTQPTQIVAGSQAGSKWMSDDLYDRASSQDKRYHIV
                     EGANHMDLYDGKAYVAEAISVLAPFFEETL"
     gene            15823..15960
                     /locus_tag="RH288_000471"
                     /pseudo
     CDS             15823..15960
                     /locus_tag="RH288_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707232.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dehydratase"
     gene            16087..16815
                     /gene="mpaA"
                     /locus_tag="RH288_000472"
     CDS             16087..16815
                     /gene="mpaA"
                     /locus_tag="RH288_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HDV4029569.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLI
                     LAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFP
                     AANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
                     ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDE
                     ASEKYLFAMANLLRWHPKDAIRPS"
     gene            complement(16790..17755)
                     /gene="ycjG"
                     /locus_tag="RH288_000473"
     CDS             complement(16790..17755)
                     /gene="ycjG"
                     /locus_tag="RH288_000473"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415841.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HDV4029570.1"
                     /translation="MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEEGIKGTGE
                     CTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGAARNALDCALWDLAARR
                     QQQSLADLIGITLPETVITAQTVVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
                     MVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFSLMLGCM
                     LCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL"
     gene            17874..18380
                     /gene="tpx"
                     /locus_tag="RH288_000474"
     CDS             17874..18380
                     /gene="tpx"
                     /locus_tag="RH288_000474"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HDV4029571.1"
                     /translation="MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNN
                     VITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
                     AALAVLKA"
     gene            complement(18424..19965)
                     /gene="tyrR"
                     /locus_tag="RH288_000475"
     CDS             complement(18424..19965)
                     /gene="tyrR"
                     /locus_tag="RH288_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HDV4029572.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFA
                     ELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKV
                     DMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
                     ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVE
                     QAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRAGKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVR
                     VICATQKNLVELVQKGMFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKNEE"
     gene            complement(20113..21174)
                     /locus_tag="RH288_000476"
     CDS             complement(20113..21174)
                     /locus_tag="RH288_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HDV4029573.1"
                     /translation="MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDE
                     AQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
                     QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRR
                     QLIGQVKETLQKGKTPSEK"
     gene            complement(21171..22568)
                     /locus_tag="RH288_000477"
     CDS             complement(21171..22568)
                     /locus_tag="RH288_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HDV4029574.1"
                     /translation="MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFTYDEGLAQLYGDPPAWPTPTRGV
                     SEIRLALRFKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
                     NGQRGEWSAKWRMMSEGLDPLAPADENRLADIAAAWTDYLHHCKEQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDTWGESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGIIDVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            22724..23722
                     /locus_tag="RH288_000478"
     CDS             22724..23722
                     /locus_tag="RH288_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV4029575.1"
                     /translation="MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEEL
                     QYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQT
                     SHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYDIPVVVIGKVEGQYAHV
                     YSVDTDNFGDSIALTDALIESGHQNIACLHAPLDVHVSVDRVNGYKQSLAAHNIAVRD
                     EWIVDGGYTHETALKAARQLLSQSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAV
                     VGYSNETLSFILTPAPGGIDVPTQELGQQSCELLFRLISGKPSPQNITVATHMTLK"
     gene            complement(23833..24738)
                     /gene="ompG"
                     /locus_tag="RH288_000479"
     CDS             complement(23833..24738)
                     /gene="ompG"
                     /locus_tag="RH288_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric porin OmpG"
                     /protein_id="HDV4029576.1"
                     /translation="MKKLLPCTALVMCAGMACAQAEEKNDWHFNIGAMYEIENVEGYG
                     EDMDGLAEPSVYFNAANGPWRIALAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLESD
                     DFSFGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
                     DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYL
                     PLTLGNHSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYA
                     FEWQDHDEGDSDKFHYAGVGVNYSF"
     gene            complement(24783..25865)
                     /locus_tag="RH288_000480"
     CDS             complement(24783..25865)
                     /locus_tag="RH288_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4029577.1"
                     /translation="MAQLSLQHIQKIYDNQVHVVKDFNLEIADKEFIVFVGPSGCGKS
                     TTLRMIAGLEEISGGDLLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLK
                     MQKIAKEVIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
                     PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGA
                     PKTVYNQPANMFVAGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQESLH
                     KPIVMGIRPEDIHPDAQEENNISAKISVAELTGAEFMLYTTVGGHELVVRAGALNDYH
                     AGENITIHFDMTKCHFFDAETEIAIR"
     gene            complement(25879..26538)
                     /gene="pgmB"
                     /locus_tag="RH288_000481"
     CDS             complement(25879..26538)
                     /gene="pgmB"
                     /locus_tag="RH288_000481"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDV4029578.1"
                     /translation="MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESL
                     KGISRDESLRRILQHGGKEGDFNPQERAQLAYRKNMLYVHSLRELTVNAVLPGIRSLL
                     ADLRAQQISVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
                     GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTESLTWPRLSAFWQN
                     V"
     gene            complement(26535..28802)
                     /gene="ycjT"
                     /locus_tag="RH288_000482"
     CDS             complement(26535..28802)
                     /gene="ycjT"
                     /locus_tag="RH288_000482"
                     /EC_number="2.4.1.230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707222.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kojibiose phosphorylase"
                     /protein_id="HDV4029579.1"
                     /translation="MTRPVTLSEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQ
                     TRGMYLAGLYHRAGKGEINELVNLPDILGMEIAINGEVFSLSREAWQRELDFASGELR
                     RSVVWRTSNGAGYTIASRRFVSAEQLSLMALEISITPLDAEASVLLSTGIDATQTNHG
                     RQHLDETQVRVFGQHLMQGIYTTQDGRSDVAISCCCQVRGDVQQCYTAKERRLLQHTS
                     AQLRAGETLTLQKLVWIDWRDDRQAALDEWGSASLRQLAMCAQQSYDQLLAASTENWR
                     QWWQKRRITVNGGDAHDQQALDYALYHLRIMTPAHDERSSIAAKGLTGEGYKGHVFWD
                     TEVFLLPFHLFSDPTVARSLLRYRWHNLSGAQEKARRNGWQGALFPWESARSGEEETP
                     EFAAINIRTGLRQKVASAQAEHHLVADIAWAVIQYWQTTGDESFIAHEGMALLLETAK
                     FWISRAVRVNDRLEIHDVIGPDEYTEHVNNNAFTSYMAYYNVQQALSIARQFGCSDDA
                     FIHRAEMFLKELRLPEIQPDGVLPQDDSFMAKPAINLAKYKAAAGKQTILLDYSRAEV
                     NEMQILKQADVVMLNYMLPEQFSAASCLANLQFYEPRTIHDSSLSKAIHGIVAARCGL
                     LTQSYQFWREGTEIDLGADPHSCDDGIHAAATGAIWLGAIQGFAGVSVRDGELHLNPA
                     LPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSLRLNGQLISVAEESVFCLGDF
                     ILPFNGTATTHQEDE"
     gene            complement(28799..29854)
                     /locus_tag="RH288_000483"
     CDS             complement(28799..29854)
                     /locus_tag="RH288_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDV4029580.1"
                     /translation="MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSR
                     LSQAQALADKYGNASVWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCE
                     KPPAMTPQQAREMCDTARKLGKVLAYDFHHRFALDTQQLREQVTNGVLGEIYVTTARA
                     LRRCGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVNAHSFQKIGTQK
                     SCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGA
                     TLFPAHIYTDNNGELMTLMQREMADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQ
                     LVAALYQSAETGTRVEL"
     gene            complement(29864..30652)
                     /locus_tag="RH288_000484"
     CDS             complement(29864..30652)
                     /locus_tag="RH288_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDV4029581.1"
                     /translation="MKIGTQNQAFFPENILEKFRYIKEMGFDGFEIDGKLLVNNIGEV
                     KAAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAW
                     GMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLA
                     DARRYIVENNLKHVQIIGDFYHMNIEEDNLAQALHDNRDLLGHVHIADNHRYQPGSGT
                     LDFHALFEQLRADNYQGYVVYEGRIRAEDPAQAYRDSLAWLRTC"
     gene            complement(30670..31722)
                     /locus_tag="RH288_000485"
     CDS             complement(30670..31722)
                     /locus_tag="RH288_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDV4029582.1"
                     /translation="MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVD
                     FRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVG
                     DSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
                     VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEI
                     KTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNN
                     AKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFANSPESYMQ
                     YVDQHPEQSIKMGVTF"
     gene            complement(31753..32595)
                     /locus_tag="RH288_000486"
     CDS             complement(31753..32595)
                     /locus_tag="RH288_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDV4029583.1"
                     /translation="MATNKRTLSRIGFYCGLALFLIITLFPFFVMLMTSFKSAKEAIS
                     LHPTLLPQQWTLEHYVDIFNPMIFPFVDYFRNSMVVSVVSSVVAVFLGILGAYALSRL
                     RFKGRMTINASFYTVYMFSGILLVVPLFKIITALGIYDTEMALIITMVTQTLPTAVFM
                     LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFAS
                     IFLSSASNFTLPVGLNALFSTPDYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAG
                     GVKG"
     gene            complement(32582..33463)
                     /locus_tag="RH288_000487"
     CDS             complement(32582..33463)
                     /locus_tag="RH288_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDV4029584.1"
                     /translation="MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRL
                     PLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYTALVVAGSTVLGLAVAMFFNREF
                     RLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
                     SSFVLVVLFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMP
                     VLATVVTLRTIWMFYMFADVYLLTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIII
                     FAVILLTRKRVNLNGNK"
     gene            complement(33484..34776)
                     /locus_tag="RH288_000488"
     CDS             complement(33484..34776)
                     /locus_tag="RH288_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV4029585.1"
                     /translation="MIKSKIVLLSALVSCALISGCKEENKTNVSIEFMHSSVEQERQA
                     VISKLIARFEKENPGITVKQVPVEEDAYNTKVITLSRSGSLPEVIETSHDYAKVMDKE
                     QLIDRKAVATVISNVGEGAFYDGVLRIVRTEDGSAWTGVPVSAWIGGIWYRKDVLAKA
                     GLEEPKNWQQLLDVAQKLNDPANKKYGIALPTAESVLTEQSFSQFALSNQANVFNAEG
                     KITLDTPEMMQALTYYRDLAANTMPGSNDIMEVKDAFMNGTAPMAIYSTYILPAVIKE
                     GDPKNVGFVVPTEKNSAVYGMLTSLTITAGQKTEETEAAEKFVTFMEQADNIADWVMM
                     SPGAALPVNKAVVTTATWKDNDVIKALGELPNQLIGELPNIQVFGAVGDKNFTRMGDV
                     TGSGVVSSMVHNVTVGKADLPGTLQASQKKLDELIEQH"
     gene            complement(34790..36469)
                     /gene="ycjM"
                     /locus_tag="RH288_000489"
     CDS             complement(34790..36469)
                     /gene="ycjM"
                     /locus_tag="RH288_000489"
                     /EC_number="2.4.1.352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415825.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosylglycerate phosphorylase"
                     /protein_id="HDV4029586.1"
                     /translation="MKQKITDYLDEIYGGTFTATHLQKLVTRLESAKRLITQRRKKHW
                     DESDVVLITYADQFHSNDLKPLPTFNQFYHQWLQSIFSHVHLLPFYPWSSDDGFSVID
                     YHQVASEAGEWQDIQQLGECSHLMFDFVCNHMSAKSEWFKNYLQQHPGFEDFFIAVDP
                     QTDLSAVTRPRALPLLTPFQMRDHSTRHLWTTFSDDQIDLNYRSPEVLLAMVDVLLCY
                     LAKGAEYVRLDAVGFMWKEPGTSCIHLEKTHLIIKLLRSIIDNVAPGTVIITETNVPH
                     KDNIAYFGAGDDEAHMVYQFSLPPLVLHAVQKQNVEALCAWAQNLTLPSSNTTWFNFL
                     ASHDGIGLNPLRGLLPESEILELVEALQQEGALVNWKNNPDGTRSPYEINVTYMDALS
                     RRESSDEERCARFILAHAILLSFPGVPAIYIQSILGSRNDYAGVEKLGYNRAINRKKY
                     HSKEITRELNDEATLRHAVYHELSRLITLRRSHNEFHPDNNFTIDTINSSVMRIQRSN
                     ADGNCLTGLFNVSKNIQHVNITNLHGRDLISEVDILGNEITLRPWQVMWIK"
     gene            complement(36682..36996)
                     /gene="pspE"
                     /locus_tag="RH288_000490"
     CDS             complement(36682..36996)
                     /gene="pspE"
                     /locus_tag="RH288_000490"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HDV4029587.1"
                     /translation="MFKKGLLALALVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIP
                     LKEVKERIATAVPDKNDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGGLKDIAMPKV
                     KG"
     gene            complement(37071..37292)
                     /gene="pspD"
                     /locus_tag="RH288_000491"
     CDS             complement(37071..37292)
                     /gene="pspD"
                     /locus_tag="RH288_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HDV4029588.1"
                     /translation="MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVA
                     RRPLKMLLAVALEPLLSRAANKLAQRYKR"
     gene            complement(37301..37660)
                     /gene="pspC"
                     /locus_tag="RH288_000492"
     CDS             complement(37301..37660)
                     /gene="pspC"
                     /locus_tag="RH288_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HDV4029589.1"
                     /translation="MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLS
                     IFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            complement(37660..37884)
                     /gene="pspB"
                     /locus_tag="RH288_000493"
     CDS             complement(37660..37884)
                     /gene="pspB"
                     /locus_tag="RH288_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HDV4029590.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLA
                     QLADEAKRMRERIQALESILDAEHPNWRDR"
     gene            complement(37938..38606)
                     /gene="pspA"
                     /locus_tag="RH288_000494"
     CDS             complement(37938..38606)
                     /gene="pspA"
                     /locus_tag="RH288_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HDV4029591.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     STSARALAEKKQLTRRIEQASAREVEWQEKAELALLKEREDLARAALIEKQKLTDLIK
                     SLEHEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMK
                     QDNQ"
     gene            38773..39750
                     /gene="pspF"
                     /locus_tag="RH288_000495"
     CDS             38773..39750
                     /gene="pspF"
                     /locus_tag="RH288_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415819.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HDV4029592.1"
                     /translation="MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKEL
                     IASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
                     FRADLLDRLAFDVVQLPPLRERESDIMLMAEYFAIQMCREIKLPLFPGFTERARETLL
                     NYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRPPEDAIAVSETTSLPTLP
                     LDLREFQMQQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI"
     gene            complement(39870..41135)
                     /gene="puuE"
                     /locus_tag="RH288_000496"
     CDS             complement(39870..41135)
                     /gene="puuE"
                     /locus_tag="RH288_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate transaminase"
                     /protein_id="HDV4029593.1"
                     /translation="MSNNEFHQRRLSATPRGVGVMCNFFAQSAENATLKDVEGNEYID
                     FAAGIAVLNTGHRHPDLVAAVEQQLQQFTHTAYQIVPYESYVTLAEKINALAPVSGQA
                     KTAFFTTGAEAVENAVKIARAHTGRPGVIAFSGGFHGRTYMTMALTGKVAPYKIGFGP
                     FPGSVYHVPYPSDLHGISTQDSLDAIERLFKSDIEAKQVAAIIFEPVQGEGGFNVAPK
                     ELVAAIRRLCDEHGIVMIADEVQSGFARTGKLFAMDHYADKPDLMTMAKSLAGGMPLS
                     GVVGNANIMDAPAPGGLGGTYAGNPLAVAAAHAVLNIIDKESLCERANQLGQRLKNTL
                     IDAKESVPAIAAVRGLGSMIAVEFNDPQTGEPSAAIAQKIQQRALAQGLLLLTCGAYG
                     NVIRFLYPLTIPDAQFDAAMKILQDALSD"
     gene            complement(41173..42453)
                     /gene="puuB"
                     /locus_tag="RH288_000497"
     CDS             complement(41173..42453)
                     /gene="puuB"
                     /locus_tag="RH288_000497"
                     /EC_number="1.4.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylputrescine oxidase"
                     /protein_id="HDV4029594.1"
                     /translation="MTEHTSSYYAASANKYAPFDTLNESITCDVCVVGGGYTGLSSAL
                     HLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMDTARMLGSMMFE
                     GGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYGNKQLELLDANAI
                     RREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQIQHTTPAVV
                     RTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQVITTERLSEDLARSLIPKNY
                     CVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLVVPKLLKTFPQLKGVKIDY
                     RWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHLAGRLIAELLRGDAERFDAF
                     ANLPHYPFPGGRTLRVPFTAMGAAYYSLRDRLGV"
     gene            complement(42455..43942)
                     /gene="puuC"
                     /locus_tag="RH288_000498"
     CDS             complement(42455..43942)
                     /gene="puuC"
                     /locus_tag="RH288_000498"
                     /EC_number="1.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase PuuC"
                     /protein_id="HDV4029595.1"
                     /translation="MNFHHLAYWQDKALSLAIENRLFINGEYTAAAENEAFETVDPVT
                     QAPLAKIARGKSVDIDRAMSAARGVFERGDWSLSSPAKRKAVLNKLADLMEAHAEELA
                     LLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGV
                     IAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLSAIRLAGLAKEAGLPDGVLN
                     VVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANIV
                     FADCPDLQQAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLALLKQQAQNWQPGHP
                     LDPATTMGTLIDCAHADSVHSFIREGESKGQLLLDGRNAGLAAAIGPTIFVDVDPNAS
                     LSREEIFGPVLVVTRFTSEEQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVF
                     VNNYNDGDMTVPFGGYKQSGNGRDKSLHALEKFTELKTIWISLEA"
     gene            complement(44217..44774)
                     /gene="puuR"
                     /locus_tag="RH288_000499"
     CDS             complement(44217..44774)
                     /gene="puuR"
                     /locus_tag="RH288_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PuuR"
                     /protein_id="HDV4029596.1"
                     /translation="MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDK
                     VSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVINQDDLIEMGSQGVSMKLVHNGN
                     PNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINT
                     GIPHSFSNTSAGICRIISAHTPTTF"
     gene            complement(44801..45565)
                     /gene="puuD"
                     /locus_tag="RH288_000500"
     CDS             complement(44801..45565)
                     /gene="puuD"
                     /locus_tag="RH288_000500"
                     /EC_number="3.5.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415814.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase"
                     /protein_id="HDV4029597.1"
                     /translation="MENIMNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIA
                     LPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPGRDLLSMAIINA
                     ALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQ
                     VEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALG
                     VQWHPEWNSSEYALSRILFEGFITACQHHIAEKQRL"
     gene            45777..47195
                     /gene="puuA"
                     /locus_tag="RH288_000501"
     CDS             45777..47195
                     /gene="puuA"
                     /locus_tag="RH288_000501"
                     /EC_number="6.3.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415813.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-putrescine ligase"
                     /protein_id="HDV4029598.1"
                     /translation="METNIVEVENFVQQSEERRGSAFTQEVKRYLERYPNTQYVDVLL
                     TDLNGCFRGKRIPVSSLKKLEKGCYFPASVFAMDILGNVVEEAGLGQEMGEPDRTCVP
                     VLGSLTPSAADPEFIGQMLLTMVDEDGAPFDVEPRNVLNRLWQQLRQRGLFPVVAVEL
                     EFYLLDRQRDAEGYLQPPCAPGTDDRNTQSQVYSVDNLNHFADVLNDIDELAQLQLIP
                     ADGAVAEASPGQFEINLYHTDNVLEACDDALALKRLVRLMAEKHKMHATFMAKPYEEH
                     AGSGMHIHISMQNNRGENVLSDAEGEDSPLLKKMLAGMIDLMPSSMALLAPNVNSYRR
                     FQPGMYVPTQASWGHNNRTVALRIPCGDRHNHRVEYRVAGADANPYLVMAAIFAGILH
                     GLDNELPLQEEVEGNGLEQEGLPFPIRQSDALGEFIENDHLRRYLGERFCHVYHACKN
                     DELLQFERLITETEIEWMLKNA"
     gene            47344..47508
                     /locus_tag="RH288_000502"
     CDS             47344..47508
                     /locus_tag="RH288_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029599.1"
                     /translation="MPMIKSPHGEGGCVCAPPATDWTPPPLLPLLNRFDFRSTRPQTL
                     LRRGGSKYGY"
     gene            47498..48883
                     /gene="puuP"
                     /locus_tag="RH288_000503"
     CDS             47498..48883
                     /gene="puuP"
                     /locus_tag="RH288_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415812.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PuuP"
                     /protein_id="HDV4029600.1"
                     /translation="MAINSPLNIAAQPGKTRLRKSLKLWQVVMMGLAYLTPMTVFDTF
                     GIVSGISDGHVPASYLLALAGVLFTAISYGKLVRQFPEAGSAYTYAQKSINPHVGFMV
                     GWSSLLDYLFLPMINVLLAKIYLSALFPEVPPWVWVVTFVAILTAANLKSVNLVANFN
                     TLFVLVQISIMVVFIFLVVQGLHKGEGVGTVWSLQPFISENAHLIPIITGATIVCFSF
                     LGFDAVTTLSEETPDAARVIPKAIFLTAVYGGVIFIAASFFMQLFFPDISRFKDPDAA
                     LPEIALYVGGKLFQSIFLCTTFVNTLASGLASHASVSRLLYVMGRDNVFPERVFGYVH
                     PKWRTPALNVIMVGIVALSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMN
                     KSWKDHFHYLLMPLVGALTVGVLWVNLESTSLTLGLVWASLGGAYLWYLIRRYRKVPL
                     YDGDRTPVSET"
     gene            49017..49262
                     /locus_tag="RH288_000504"
     CDS             49017..49262
                     /locus_tag="RH288_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmjA family protein"
                     /protein_id="HDV4029601.1"
                     /translation="MNHDIPLKYFDIADEYATECAEPVAEAERTPLAHYFQLLLTRLM
                     NNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE"
     gene            49575..51218
                     /gene="sapA"
                     /locus_tag="RH288_000505"
     CDS             49575..51218
                     /gene="sapA"
                     /locus_tag="RH288_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HDV4029602.1"
                     /translation="MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQV
                     NTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRR
                     DVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSV
                     RKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYARKLEKEDRQEQLDRQPVGTGPY
                     QLSEYRAGQFIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAAS
                     QLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYG
                     TAETAASILPRASWAYDNEAKITEYNPAKSREQLKSLGLENLTLKLWVPTRSQAWNPS
                     PLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRP
                     LLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLA
                     SSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP"
     gene            51215..52180
                     /gene="sapB"
                     /locus_tag="RH288_000506"
     CDS             51215..52180
                     /gene="sapB"
                     /locus_tag="RH288_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HDV4029603.1"
                     /translation="MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMELCILAFGFALIVGIPVGMIAGIT
                     RHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
                     LIDAWLSDSPWRDEMIMSAIRHMILPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAI
                     RQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYALR"
     gene            52167..53057
                     /gene="sapC"
                     /locus_tag="RH288_000507"
     CDS             52167..53057
                     /gene="sapC"
                     /locus_tag="RH288_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HDV4029604.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCI
                     FGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
                     AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMIS
                     VLLVNLLGDGVRRAIIAGVE"
     gene            53057..54049
                     /gene="sapD"
                     /locus_tag="RH288_000508"
     CDS             53057..54049
                     /gene="sapD"
                     /locus_tag="RH288_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HDV4029605.1"
                     /translation="MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGS
                     GKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE"
     gene            54051..54857
                     /gene="sapF"
                     /locus_tag="RH288_000509"
     CDS             54051..54857
                     /gene="sapF"
                     /locus_tag="RH288_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HDV4029606.1"
                     /translation="MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR"
     gene            54925..55278
                     /locus_tag="RH288_000510"
     CDS             54925..55278
                     /locus_tag="RH288_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF559 domain-containing protein"
                     /protein_id="HDV4029607.1"
                     /translation="MIDKIKSNARDLRRNLTLQERKLWRYLRSRRFSDFKFRRQHPVG
                     SYILDFACCSARVVVELDGGQHDLAVAYDSRRTSWLESQGWTVLRFWNNEIDCNEETV
                     LENILQELNRRSPSP"
     gene            55646..56434
                     /gene="fabI"
                     /locus_tag="RH288_000511"
     CDS             55646..56434
                     /gene="fabI"
                     /locus_tag="RH288_000511"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDV4029608.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            56578..57705
                     /locus_tag="RH288_000512"
     CDS             56578..57705
                     /locus_tag="RH288_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CMD domain-containing protein"
                     /protein_id="HDV4029609.1"
                     /translation="MEQRHITGKSHWYHETQSSTTEYDVLPLVPEAAKVSDPFLLDVI
                     LEKETLAPFLSWLDPARVLAVDLFPDQLTVTRSQTFTAYERLSTALTVAQVCGVQRLC
                     NYYSARLTPLPGPDSTRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTAWDC
                     VIISQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESLRWRSSYEV
                     EKLPEEHTKSSTAELCQLAEILSLHPISLSLLEKLLNSTRGNTQPDNQLAALLCARIN
                     GSPACFATCMDSSNEYKKISTLMRKGENEINQWADRHSVERATVQAIQWLTRAPDRFS
                     AAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY"
     gene            57773..59707
                     /gene="rnb"
                     /locus_tag="RH288_000513"
     CDS             57773..59707
                     /gene="rnb"
                     /locus_tag="RH288_000513"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HDV4029610.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPD
                     HPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
                     WWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALP
                     DDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIA
                     EQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA
                     MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFC
                     KLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAA
                     EIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVI
                     DVTIAEVRMETRSIIARPVA"
     gene            complement(59785..59889)
                     /locus_tag="RH288_000514"
     CDS             complement(59785..59889)
                     /locus_tag="RH288_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029611.1"
                     /translation="MTYMKLTAAKRIVFFIYLFVIQFWKNASFQTKVS"
     gene            59943..61928
                     /gene="pdeR"
                     /locus_tag="RH288_000515"
     CDS             59943..61928
                     /gene="pdeR"
                     /locus_tag="RH288_000515"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HDV4029612.1"
                     /translation="MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTETTEPDRTL
                     QLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLVGRKINKREWAGNASAWHDTPAV
                     ARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLF
                     MSRREAAASRRNNRVFFRSGNAYEVELWIPTCKGQRLFLFRNKFVHSGSGKNEIFLIC
                     SGTDITEERRAQERLRILANTDSITGLPNRNAMQDLIDHAINHADNNKVGVVYLDLDN
                     FKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMA
                     SRILTRLRLPFRIGLIEVYTSCSVGIALSPEHGSDSTAIIRHADTAMYTAKEGGRGQF
                     CVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPER
                     GLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQT
                     IFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTGY
                     SSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKE
                     DAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA"
     gene            62076..62249
                     /locus_tag="RH288_000516"
     CDS             62076..62249
                     /locus_tag="RH288_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029613.1"
                     /translation="MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVA
                     ESTPDIPKAPWEI"
     gene            62339..63088
                     /locus_tag="RH288_000517"
     CDS             62339..63088
                     /locus_tag="RH288_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV4029614.1"
                     /translation="MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKL
                     SYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLA
                     RTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
                     SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVE
                     RFNRVITDSKIRASDLMHLEHSKLTVHVVDI"
     gene            63357..63575
                     /gene="osmB"
                     /locus_tag="RH288_000518"
     CDS             63357..63575
                     /gene="osmB"
                     /locus_tag="RH288_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HDV4029615.1"
                     /translation="MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAVGGVIGHQVGK"
     gene            complement(63701..64027)
                     /gene="yciH"
                     /locus_tag="RH288_000519"
     CDS             complement(63701..64027)
                     /gene="yciH"
                     /locus_tag="RH288_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HDV4029616.1"
                     /translation="MSDSNSRLVYSTETGRIDEPKAAPVRPKGDGVVRIQRQTSGRKG
                     KGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGVIEIQGDKRDLLKSLLEAKGMK
                     VKLAGG"
     gene            complement(64027..64764)
                     /gene="pyrF"
                     /locus_tag="RH288_000520"
     CDS             complement(64027..64764)
                     /gene="pyrF"
                     /locus_tag="RH288_000520"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDV4029617.1"
                     /translation="MTLTASSSSRAVTNSPVVVALDYHNRDDALAFVDKIDPRDCRLK
                     VGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASG
                     GARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLVDLGMTLSPADYAERLAALTQK
                     CGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYM
                     VIGRPVTQSVDPAQTLKAINASLQRSA"
     gene            complement(64958..66127)
                     /gene="lapB"
                     /locus_tag="RH288_000521"
     CDS             complement(64958..66127)
                     /gene="lapB"
                     /locus_tag="RH288_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HDV4029618.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKA
                     IDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSI
                     MMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAV
                     EENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL"
     gene            complement(66134..66442)
                     /gene="lapA"
                     /locus_tag="RH288_000522"
     CDS             complement(66134..66442)
                     /gene="lapA"
                     /locus_tag="RH288_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA"
                     /protein_id="HDV4029619.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVVPHSSAAKE
                     "
     gene            complement(66591..67355)
                     /gene="pgpB"
                     /locus_tag="RH288_000523"
     CDS             complement(66591..67355)
                     /gene="pgpB"
                     /locus_tag="RH288_000523"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HDV4029620.1"
                     /translation="MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWV
                     TETVTQPWGVITHLILFGWFLWCLRFRIKAAFVLFAILAAAILVGQGVKSWIKDKVQE
                     PRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWALVAVATWLAQRICGPLTPPAEENREIAQREQES"
     gene            67525..68115
                     /gene="ribA"
                     /locus_tag="RH288_000524"
     CDS             67525..68115
                     /gene="ribA"
                     /locus_tag="RH288_000524"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HDV4029621.1"
                     /translation="MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTE
                     AGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK"
     gene            complement(68179..70854)
                     /gene="acnA"
                     /locus_tag="RH288_000525"
     CDS             complement(68179..70854)
                     /gene="acnA"
                     /locus_tag="RH288_000525"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HDV4029622.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKV
                     LLENLLRWQDGNSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSE
                     DQVELVEKYAKAQGMWRNPGDEPIFTSTLELDMNDVEASLAGPKRPQDRVALPDVPKA
                     FAASNELEVNATHKDRQPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNI
                     NLASEPIGHDRKGDPVYLKDIWPSAQEIARAVEQVSTEMFRKEYAEVFEGTAEWKGIN
                     VTRSDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTR
                     HLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSNLIGMGILPLEFPQGVTRKTLGLTGEEKIDIGDLQNLQPGATVPVTLTRADG
                     SQEVVPCRCRIDTATELTYYQNDGILHYVIRNMLK"
     gene            complement(71018..71113)
                     /locus_tag="RH288_000526"
     CDS             complement(71018..71113)
                     /locus_tag="RH288_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029623.1"
                     /translation="MINTNMKYWSWMDAFSLSMLFWAELLWIITH"
     gene            complement(71227..71394)
                     /locus_tag="RH288_000527"
     CDS             complement(71227..71394)
                     /locus_tag="RH288_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029624.1"
                     /translation="MVGQEQLESSPLCQHSDNETETKRECSVVIPDDWQLTSQQQAFI
                     ELFAEDDQPKQ"
     gene            complement(71397..71561)
                     /locus_tag="RH288_000528"
     CDS             complement(71397..71561)
                     /locus_tag="RH288_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HDV4029625.1"
                     /translation="MLISDGDYMRLAMPSGNQEPRRDPELKRKAWLAVFLGSALFWVV
                     VALLIWKVWG"
     gene            complement(71856..72830)
                     /gene="cysB"
                     /locus_tag="RH288_000529"
     CDS             complement(71856..72830)
                     /gene="cysB"
                     /locus_tag="RH288_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HDV4029626.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
                     LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIKLPEK"
BASE COUNT        17677 a        19031 c        17994 g        18227 t
ORIGIN      
        1 tctatcatta tcagaattat ctgatcatat gacgtggctt ttttgcgatc ggatagcaac
       61 aaaaattgat aaaaataacg ggatctcaat gattacgcac aacttcaata ccctggactt
      121 actcaccagt cctgtctgga tcgtttcgcc ctttgaggaa cagttaattt atgccaatag
      181 cgcggcgaaa ctgttgatgc aagacctcac gtttagtcag ctacgaaccg gaccctattc
      241 cgtctcctca caaaaagaac tgccgaaata cctctccgat ctgcaaaacc aacacgatat
      301 tatcgaaatc ctcactgttc agcgtaaaga agaggaaaca gcattgagct gtcggcttgt
      361 tttgcgaaag ctgacagaaa cagaaccggt gattattttc gaaggtatcg aagcgccggc
      421 aacgctgggt ttaaaagcca gtcgctcggc aaattatcag cgcaaaaaac aaggttttta
      481 tgcgcgcttt tttctgacta actctgcacc aatgttgttg attgacccgt cacgagatgg
      541 acaaatcgtc gatgctaacc tcgccgcgct caatttctat ggttataacc atgaaacgat
      601 gtgccagaaa catacctggg aaataaatat gctcgggcgt cgcgtcatgc ctatcatgca
      661 tgaaatctcg catttacccg gtggtcataa acctttgaat tttgttcata aactggcgga
      721 tggttcgact cgtcatgtgc agacctatgc cggaccgatt gaaatttatg gcgacaagct
      781 catgttatgt attgtgcatg atattactga gcaaaaacgg ctggaggagc agctggaaca
      841 tgctgctcac catgacgcga tgaccggatt actgaatcgg cgacagtttt atcacattac
      901 ggaaccaggc caaatgcagc atctcgccat cgctcaggat tacagcttgt tgctcatcga
      961 caccgatcgt tttaaacaca ttaacgatct ctatgggcat tctaaaggtg atgaggtgtt
     1021 atgcgccctc gcccgcaccc tcgaaagttg cgctcgcaaa ggcgatttgg tgtttcgttg
     1081 gggaggcgaa gagtttgtct tattgctacc aagaacccca ctggataccg cgctttcgct
     1141 ggctgaaact atccgcgtaa gcgtggcaaa agtgagtatt tcgggcttac cacgctttac
     1201 cgtcagcatt ggtgtggcgc atcacgaagg aaatgaaagc atcgatgaac tgtttaaacg
     1261 cgttgatgat gctttgtatc gggcgaaaaa tgatggacgc aaccgcgtgc tggcggcata
     1321 agccgcggat gcgtctcgag atcaacgact gcgcttagcg tggcgctccc agttttcttg
     1381 cttcgcctgc gccgttttac gtagtgcgac gtaacacgcc ccgctgccgc catgatgcgg
     1441 tagcgcggtg caatatgcct gaacatcatc aaattcggtc agccagcgcg ccacatagct
     1501 gcggacaata ttggcatgcg atttatcatc ccgcccttta ccatgaataa tcagcacgtt
     1561 acgcaaacca tccgccaggg cttgttgaat aaaactgaac accattttgc ggcactcttc
     1621 caccggctgg cgcaaaagat tcaggctcgc ctgttgcgga tatttaccac tgcgcagctt
     1681 atccagcacc ccatgttgca acccttcccg ccgaaactcc agcggctgac ttagtgggat
     1741 gatgtcgaga aatccggtgg tgaggaaatt atcaagctgc agcgtgtcga tacgctgcgg
     1801 cgcacgttgg ttacgcgttg gatgccagtg gacatcggta gcacgtttca gcggctggac
     1861 atcttccatg gcgtcaagaa acagcgattt gtcgtcaagg ttcatgttac atcctcccgc
     1921 aattaagagc gcgatatgat aaccagaccg ggtcggtcca acaacgtatt acccaaattt
     1981 ccagtaataa gttccaaata ttgccgatat tttaagcaaa atacttatgc atgattattc
     2041 attcacgata ttaataatgt aacttatatt ttcgtgaaat ctgtcactga agaaaattgg
     2101 caactaaagg ttaaaaccgt tataacacag tcaccggcgc agaggagaca atgccggatt
     2161 taagacgcgg atgcactgct gtgtgtactg tagagtctgg cggatgtcga cagactctat
     2221 ttttttatgc agttttaact ttgcagatag ccgcattctc gccggaattg cgtgattaat
     2281 gacgcggtca gtggtgtctg gcgactatca cgccgctgaa tcaaataata ggccgctttc
     2341 ggtaaaattt cgctaaccgg caacatcacc agcccctgtc cgtgcaaggg atcgcagccc
     2401 atttcttcag gcagtatgct gagaaaatcg ctttttgcca ccagactgat acaggctgag
     2461 aacgtctcgc agactacacc gacctgtggc gtttgcgcct gatcgtcaag caattcactc
     2521 aactgtttgt agtagctgcc gtgtggcgtc ggcattgtcc agctgtaatc cagtaactgt
     2581 ttgatcgaac gggcaccaat ggcggggtgt cccgggcggc aaaagatcgc gaattgcttt
     2641 tccagtaatt tctcaaaagt aaattcgtgg tcgtacggtc cctgataata ggtattgatg
     2701 gtgaaatcca attctccctg acgcaattca ttaatcatcg acaccagttg cccttccata
     2761 atgcgtactt ttacctgcgg atgctgctga tgaaaacgag atatgacagc tggcatcaga
     2821 ctgcgggaaa tactggcccc catgccgata ttaatctgcc ctgccagttg cccttgtcgt
     2881 tggcgaatat cctcttgggc tgcgcgcagc tcttcaagaa ttagactggc gtgctgataa
     2941 aaactttcac cggcatcagt taacgtcacg cctttactac ggcgaaaaaa gagttgcgcc
     3001 gctaaccctt cttctagctc ctgaatagat ttactcagtg ccggttgcga catattcaac
     3061 attcggctcg ctccgcgaat gctgccctga cgagccactt caacaaaagc ccgaatttga
     3121 tgaattttta cctgaaaagc catgacgcca ccgataaccg ttatttatca gaccaaagaa
     3181 actggcatct actttaatgc agatgattgt gtcagggtaa tttatgaacg gttaaaactg
     3241 tgaaaaatca gttagtgata agtaaaaact atcgctacgt gaaccgggtc acacttttta
     3301 ctgatgacgg gaaaggttat ggagtctttg aatcaatttg ttaattcgct tgccccaaaa
     3361 ttatcgcact ggcgacgtga ttttcatcac tatgcagagt ctggctgggt ggaattccgc
     3421 actgccaccc ttgttgcgga agaattgcac cagctcggct attcactggc gctgggtcgc
     3481 gaagtagtta atgaaagtag ccggatggga ttacctgatg aattcactct acaacgcgaa
     3541 ttcgagcgcg ctcgtcaaca gggtgcgcta gcacaatgga ttgcggcttt tgaaggtggt
     3601 ttcactggta tcgttgccac cctggatacc ggtcgccccg gtccggtgat ggctttccgt
     3661 gtcgatatgg acgcgctgga tctcagtgaa gagcaggatg tcagccatcg cccctaccgc
     3721 gacggttttg cgtcatgtaa cgccggaatg atgcatgcct gtggtcatga tggacatacc
     3781 gccattgggc ttgggctggc gcataccctt aaacagttcg agtccggact acatggcgtc
     3841 atcaaactga tttttcagcc tgcagaggaa ggtacgcgtg gcgcgcgggc gatggtcgat
     3901 gcaggtgtcg tagatgatgt tgattatttt actgccgtgc acattggcac tggcgtacct
     3961 gcgggcaccg tggtgtgcgg cagtgataat tttatggcaa ccaccaaatt tgacgcgcac
     4021 ttcaccggta ccgccgctca cgcaggcgca aaaccagaag acggtcacaa tgccttgttg
     4081 gcggcagcac aagccactct tgcactgcat gcaatcgccc cgcacagcga aggagcttcc
     4141 agagtaaacg tgggcgttat gcaggcagga agcggtcgta acgttgttcc tgcctcggcg
     4201 ttgctgaaag tggaaacacg cggggccagc gacgtcatta atcaatatgt ttttgaccgt
     4261 gcacaacaag cgattcaggg cgcagcaacc atgtatggtg tcggcgttga aactcgtctg
     4321 atgggtgcag ctaccgccag ttctccttcg ccgcaatggg tcgcatggtt gcaaagtcag
     4381 gcggctcagg tcgcgggggt caatcaggcc attgaacgtg ttgaagcgcc tgcgggttcc
     4441 gaagatgcca cattaatgat ggcccgcgtg cagcaacatc aagggcaagc ctcctacgtg
     4501 gtgtttggca cacagctggc ggcaggtcat cacaacgaaa aattcgattt tgacgagcag
     4561 gttctcgcta ttgccgtcga aacgctggcg cgcaccgcgc tcaattttcc ctggacgcga
     4621 ggtatctgat gcaggaaatc tatcgtttta tcgacgatgc gattgaagcc gatcgccaac
     4681 gttataccga tattgccgat caaatctggg atcatccaga aacacgtttt gaagagttct
     4741 ggtcagcgga gcatctggct tcggcgctgg aatctgcagg cttcaccgtt acccgcaacg
     4801 taggcaatat cccaaatgcc tttattgctt cgtttggtca aggcaaaccg gttatcgccc
     4861 tgctgggaga atatgacgcc ctggcaggtt taagtcagca agcaggttgc gcgcaaccta
     4921 catccgtgac gcccggtgaa aatggtcacg gttgcggaca caatttgctg ggaaccgccg
     4981 cctttgccgc tgcaatagcc gtcaagaaat ggctggaaca atatgggcaa ggcggcacgg
     5041 tgcgctttta tggttgtcct ggcgaagaag gcggctcggg taaaacgttc atggttcgcg
     5101 agggggtatt tgatgatgtg gatgcggcac tcacctggca cccggaagcc tttgccggta
     5161 tgttcaatac ccgcacgctg gcaaacattc aggcatcatg gcgctttaaa gggatcgcag
     5221 cacatgccgc gaattcccct catttgggac gcagcgccct tgatgccgta acgttgatga
     5281 ccactggcac caacttcctc aacgaacata ttattgaaaa agcgcgcgta cactatgcca
     5341 tcacaaatag cggcgggatc tcgcccaacg tggtccaggc gcaggcagaa gtgctttatc
     5401 ttatccgcgc ccccgaaatg accgacgtgc agcatattta tgatcgggtc gccaaaatcg
     5461 ccgaaggtgc ggcattgatg accgaaacca cggttgaatg ccgcttcgac aaagcctgtt
     5521 ccagttatct cccgaatcgc accttagaaa atgccatgta ccaggcccta tcccattttg
     5581 gtaccccgga atggaactcc gaagaactgg cttttgcgaa acaaattcag gctacgctca
     5641 cctccaacga tcggcaaaac agtctgaata atatcgccgc aaccggtggc gaaaacggca
     5701 aggtttttgc actacgtcat cgtgaaacgg tactggcgaa tgaagtcgct ccatatgccg
     5761 ccaccgataa cgtgcttgcg gcatcgactg atgtcggcga cgtcagttgg aaactgcctg
     5821 ttgcccagtg tttcagcccc tgttttgccg tcggtacacc gctacatacg tggcaactgg
     5881 ttagccaggg gcgaacatct attgctcata aaggaatgct gctggcggcg aaaactatgg
     5941 cagcaaccac agtcaatctc ttccttgatt cagggctatt gcaagaatgc caacaagagc
     6001 atcagcaagt aacggacacg caaccgtatc actgccctat cccgaaaaac gtgacaccgt
     6061 cacctttaaa ataacaacaa caacgcaaac acaacaaccg aggaatgccc atgagtatgt
     6121 catccatacc gtcgtcctcc caatccggga agctctatgg ctgggtcgaa agaattggta
     6181 acaaggttcc ccatcctttt ctgctcttta tctatttgat tatcgtactc atggtgacga
     6241 cggcaatttt gtcggccttt ggcgtcagtg cgaaaaaccc gaccgatggt acgccggtcg
     6301 tggtgaaaaa cctgctcagt gtggaaggat tacactggtt tttacccaat gttattaaaa
     6361 actttagcgg ttttgctcca cttggtgcga tcctggcgct ggttttaggt gccggtctgg
     6421 cggagcgcgt cggcttactg ccagcactaa tggttaaaat ggcatcgcat gttaatgccc
     6481 gctacgccag ttatatggtg ctgtttattg cttttttcag ccacatttct tccgatgcgg
     6541 cgttagtgat catgccaccg atgggtgcgc tgatttttct ggcggtgggc aggcatccag
     6601 ttgcaggttt actggctgcc attgcaggcg taggttgcgg ctttacggct aatttactga
     6661 ttgtcacaac cgacgtgttg ctgtcgggga tcagcacgga agcggcagct gcgttcaatc
     6721 cgcaaatgca cgtcagtgta attgataact ggtattttat ggccagctcc gtagtcgtac
     6781 tgacgattgt tggcggcctg ataaccgaca aaatcatcga gccacggtta ggtcaatggc
     6841 agggaaacag cgatgagaaa ctgcagacat tgaccgaaag tcagcgtttt ggtttacgca
     6901 tagcaggtgt cgtatcgcta ctttttattg ctgcgattgc gctgatggtg atcccgcaaa
     6961 acgggatatt gcgcgatccg attaatcaca ccgtgatgcc atcacccttt attaaaggta
     7021 tcgtgccact gatcattctt tttttctttg ttgtctcgct ggcttatggc atcgctaccc
     7081 gcacaattcg acgtcaggcg gatttaccgc atttaatgat tgaaccgatg aaagagatgg
     7141 cgggatttat cgtgatggtt tttcccctcg cccaatttgt cgccatgttt aactggagca
     7201 acatggggaa attcatcgcc gtggggctga ccgatatact ggaaagttca gggcttagcg
     7261 gcatcccggc gtttgtcggt ctggcgttgc tttcctcttt cttatgcatg tttattgcca
     7321 gcggttccgc aatctggtcg attcttgccc ccattttcgt accaatgttt atgctacttg
     7381 gctttcaccc ggcatttgcg caaatcctct ttcgtattgc cgactcatcc gtattgcctt
     7441 tagcgccggt atctcctttt gttccactgt ttcttggatt cctgcaacgc tacaaaccag
     7501 acgcgaaact gggtacttac tattcgttag tcttgcccta tccacttatc tttttggtgg
     7561 tatggctgct gatgttgctg gcgtggtatc ttgtcggtct gccgataggt ccgggtattt
     7621 acccacgttt gtcttaagag agaacggatg ctgagattac ttgaagaaaa aattgccacg
     7681 ccactgggtc cactgtgggt gatttgcgat gagcaatttc gcctgcgggc ggttgaatgg
     7741 gaagagtaca gcgaacgcat ggtgcagctg ctggacatcc attatcgcaa agaaggctat
     7801 gagcgcattt ctgccaccaa tccaggcggt ttaagcgaca agcttcgtga atattttgcc
     7861 ggtaatctta gcattattga tacgcttccc actgctacgg gggggacgcc atttcagcgc
     7921 gaagtctgga aaacactacg cactatcccc tgcgggcagg taatgcatta cggccaactg
     7981 gctgagcaat tgggccgtcc tggcgcggcg cgtgccgttg gtgcggcaaa cggatcgaat
     8041 cccatcagca tcgtcgtacc ttgccatcgg gttattggcc gaaacggcac catgaccgga
     8101 tatgcaggcg gagttcagcg aaaagagtgg ttattgcgcc atgaaggtta tcttttgctg
     8161 taaacattaa acaatttgtg ccagcttgtt cacactttta tgtaaagtta cccttaacaa
     8221 cttaagggtt ttcaaataga tagacatata tttacatcta atatcggaat tctctgctgt
     8281 taaggtttgc ttagacttac ttgctcccta aaaagatgtt aaaattgaca aatatcaatt
     8341 acggcttgag cagacctatg atcccggaaa agcgaattat acggcgcatt cagtctggcg
     8401 gttgtgctat ccattgccag gattgcagca tcagccagct ttgcatcccg ttcacactca
     8461 acgaacatga gcttgatcag cttgataata tcattgagcg gaagaagcct attcagaaag
     8521 gccagacgct gtttaaggct ggtgatgaac ttaaatcgct ttatgccatc cgttccggta
     8581 cgattaaaag ttataccatc actgagcaag gcgacgagca aatcactggt ttccatttag
     8641 caggcgacct ggtgggattt gacgccatcg gcagcggcca tcacccgagc ttcgcgcagg
     8701 cgctggaaac ctcgatggta tgtgaaatcc cgttcgaaac gctggacgat ttgtccggta
     8761 aaatgccgaa tctgcgtcag cagatgatgc gtctgatgag cggtgaaatc aaaggcgatc
     8821 aggacatgat cctgctgttg tcgaagaaaa atgccgagga acgtctggct gcattcatct
     8881 acaacctgtc ccgtcgtttt gcccaacgcg gcttctcccc tcgtgaattc cgcctgacga
     8941 tgactcgtgg cgatatcggt aactatctgg gcctgacggt agaaaccatc agccgtctgc
     9001 tgggtcgctt ccagaaaagc ggcatgctgg cagtcaaagg taaatacatc accatcgaaa
     9061 ataacgatgc gctggcccag cttgctggtc atacgcgtaa cgttgcctga tttttccgca
     9121 taactcacta tccttctgtc atatcattaa atttttctga tttattgatc tggcagaagg
     9181 ttcatcactg tttcattcac cagatatggg ttaatctttt aattacaaac tgcgttgaca
     9241 gttgttgtaa ggagaccctg tatggctatg tatcagaaca tgctcgttgt tatcgatcct
     9301 aaccaggacg accaaccagc attgcggcga gctgtttatt tacatcaacg gattggtggc
     9361 aaaattaaag cctttttgcc gatctatgac ttctcatacg aaatgaccac cctgctctcc
     9421 ccggacgaac gtaccgctat gcgtcagggc gtcatcagcc agcgtacagc ctggatccac
     9481 gagcaggcaa aatattatct caatgctggc gttcccattg aaattaaagt ggtctggcat
     9541 aaccgtcctt tcgaagccat cattcaggaa gtgatcagcg gcggacacga tttggtgcta
     9601 aaaatggcgc accaacatga ccgtctggaa gcggtgattt ttacgccaac ggactggcat
     9661 ctgttacgca aatgcccaag cccggtgtgg atggtgaaag accagccgtg gccggaagga
     9721 ggcaaggcgc tggtggcggt gaatctcgcc agtgaagagc cgtatcataa tgcgctcaat
     9781 gaaaaactgg tcaaagagac gatcgaactg gcagaacaag tcaaccatac cgaagttcat
     9841 ctggttggcg cttatccggt aacgccaatt aatatcgcga ttgaactgcc ggaatttgac
     9901 ccgagcgttt ataacgatgc cattcgtggg caacatttgc tggcaatgaa agccctgcgg
     9961 cagaaattcg gcattaatga aaacatgacg cacgtagaaa aaggtctgcc agaagaggtg
    10021 attcctgatt tggcggagca cttacaggcg gggattgtgg ttctgggcac ggtaggacgc
    10081 accggtattt cagcagcatt cctcggcaac acggcggaac aggtgattga tcatcttcgc
    10141 tgcgacctgc tggtcattaa acctgaccag tatcagacac ccgttgaact ggatgacgaa
    10201 gaagacgatt aacgactctt caataactga caaggcccga gttatcgggc ctatttttta
    10261 cttactgctc ttcgccgcca aggaaataaa ttcccaacgg gattgccagc aacacagtaa
    10321 agaccaggct ataaacaaaa atcatcgatg actgaatcac atacattgat gtcgtccact
    10381 cagacagcgg aatattgtac tgttctataa cgccgccgat ggtcgcgcga gtcacaaccg
    10441 acgccgcaat aatgaaaacc gccaacaaac caaagagaaa tttcttccct ttcgctgact
    10501 tcagtttcgc cataatcatg atgtaatcct tgtgcagaca aatttcttgt tacctaaacg
    10561 taacaatacc atgacatttc accgttgtct gctctgaaaa cctcacctct tagctggatt
    10621 tacaatcaac gcattgatta gttagctaat gttgctactt ccttccctga ctattgatga
    10681 tctgaatgaa ttgtcgcggt aaaatagccc cgccaggggt ttccggcatg acgacaatta
    10741 tctggaggag cctgataaaa caatgatcgc tgaactgttt acaaataatg cgcttaatct
    10801 ggtcattatt ttcggtagct gcgcagcatt gattctgatg agcttttggt ttcgccgtgg
    10861 aaatcgtaaa agaaaaggat ttttattcca tgcggtgcaa tttttaatct acaccataat
    10921 tatcagtgct gttggtagca ttattaatta tgttatagaa aactataaac tcaaatttat
    10981 caccccaggc gttatcgatt ttatctgtac gtccctgatt gcggttattc tgacgattaa
    11041 gctatttctg ctgattaatc agtttgaaaa acagcagatt aaaaaaggtc gcgatatcac
    11101 cagtgcgcgg attatgtcgc gtatcatcaa aatcaccatt attgtggtgc ttgttctgct
    11161 ttatggcgaa catttcggca tgagcctttc tggcttgctg acctttggtg gtattggtgg
    11221 tctggctgtc ggtatggccg gtaaagatat tctgagtaac ttcttttccg ggattatgct
    11281 ctatttcgac cgtcctttca gtattggcga ctggatccgt tcaccggaca gaaatatcga
    11341 aggtacagta gcggaaattg gctggcgaat taccaaaatt acgacctttg ataatcgtcc
    11401 attgtacgta ccgaactcgc tgttttcgtc gatcagcgta gaaaacccag gacgaatgac
    11461 caaccgccgc attaccacga ccattggttt acgttatgag gatgcggcaa aagtgggcgt
    11521 tattgtcgaa gctgtacgtg agatgctgaa aaatcacccg gccatcgacc agcgacaaac
    11581 cttactggtt tatttcaacc agtttgctga ctcttcattg aatattatgg tttattgctt
    11641 taccaaaacc acggtatggg ctgaatggct tgctgcacag caagacgttt atttgaagat
    11701 tatcgatatt gtacagtcac acggcgcgga ctttgccttc cccagccaga cgctgtatat
    11761 ggataacatt acaccgccgg aacagggtcg ctaaatcaga catcactggc gttatgcaca
    11821 agggtaacgc cagttcccat cacatcaatg cttcacaata tacatagtcc gactgtacgc
    11881 cacatcttca ggattattaa tgggataacc tttcagccac ggcttgatta atcgtccatt
    11941 ggtatattga taaattggtg caatcggtgc ttgctccatg aggatttttt ctgccgcgtt
    12001 gtaatcggca ttacgcgctt taacggtatt ttccgtcgat gcctgggcca gaactttgtc
    12061 atatgccgga ttgttaaagc gtgaaatatt tcctgaatgc gttgacgtta ataatgtcag
    12121 gaaagtggag ggttcattat aatcccccac ccacgaggcg cggataacat caaaattgcc
    12181 ggtgttacgg ctatcgatat aggttttcca ttcctgattt tgcaatttaa catctacgcc
    12241 aaggttcttt ttccacatcg atgctacagc aatcgcaatt ttttgatggt tttctgaagt
    12301 gttatacaaa agcgtcagct tcagcggttt ttgcggacca taaccagctg cgctcaacaa
    12361 agtttttgcc tgcgcattca gttcttcctg actcatttgt tcaaacggcg aaggttccgg
    12421 cgtaaatccc gcggtaacat ctggtgtaaa atgccacgct ggcttttcgc ccgtccctaa
    12481 tactttttcg gtcatcaggc ggcgatctat cgtcatactt aatgccagac gaacgcgctg
    12541 atctgccgtc ggcccttttt gcgtgttaaa cgcataataa taggtcccga gctgcggcgg
    12601 cgtataaacc tgccccggaa tatccttcaa cagcttctga tacatatttt tcgggaagga
    12661 ttcggtgata tcaatatccc ccgcgaggta acgcttagtg gctgcggatt cctgattaat
    12721 tggcaggaag gtcacttttt gcagtaccgt tttggcgtta tcccaataat gggtattcgg
    12781 taccacgacc agtttttcat tgactacgcg ctctttaaga acataagcgc cattgccgat
    12841 cagatttccg ggtttcgtcc actctttacc gctttctacg ttggcttttt gcaccgggaa
    12901 gaaggcaaag ttagcggtta aattcacaaa ccacggcaac ggtttatcaa gctgaatttt
    12961 caaagtatgg gcatcaactg cggtgacgcc aagctggtca ggcgtagctt taccatcaat
    13021 aatcgcctgt gcgttgttga ttcccgccag cgcggcaaac catgcaaatg gcgacaatgt
    13081 ttttgggtcc accagacgtt gccagctgta gacaaaatct tgcgccgtta ccggtgtgcc
    13141 atccgcccat tttgcgttat cgcgcagggt aaaagtccag atacggttgt cattactttt
    13201 ccactgagtc gcaacgccgg ggacaatctc ccctttttcg ttctgattca ccagaccttc
    13261 aaacagatcg cgaatgacct gaatctctgg caggcccacg gctttagcgg gatccagcga
    13321 cgcaggctca tctttaatgt ggcgcaccag ctcctgcttc tctgccagta ctgtgccgct
    13381 cggaacttct gcagcatacg aaagagaaat gctgctgacc aacagcgcac aacacgtgac
    13441 tgaaacagag tgcttcataa gtttccctct aaccgacatt aaaattgatg cgtaattatt
    13501 tgtttcgcct taaagaaatg caaacaactt ccatcaaaaa agtgacaaag gaagcatcaa
    13561 atgttttaag tatcaatata tcaaatcaga tttagtgtaa ataatagtct ccaaaatgcg
    13621 gtaaagcaca tagaactccg aacactacgt tcgggcttcg cacgttcaaa cccgttttcg
    13681 gtatcataat cagcatctgt cgccattgta cgaagaataa aaaatgacca aaacgttgaa
    13741 aggaactgag aatacgttaa gagaagaatt aaattaatgt atcagcaagt agtgctaaac
    13801 agcaccttta tacttcagcc tatctataaa taatgagaat gccgagccag catgtcgacg
    13861 gtgtggatag tacaggtgat aaccgggtaa atctggtgtg aatttatcca aaacacgtat
    13921 cagttttttt tctttaatag cccgctcaac ctgatcataa ggtagatacg ccaatccatg
    13981 cccatcaatt gcagcatcaa tgatcaggtc tatcgtattc agtaaaagct gaccttccat
    14041 gcgaacacga acttcacgtc caccgcgtat taatctccag cgatttgctg tacccgatgt
    14101 gggaagatac aaattaattg cctgatgatc tattaattgt gacactgacg ttggaacact
    14161 tcggcgagaa aaataatccg gtgagccaac aatagccatt ggtatatctg gcccgattcg
    14221 aatggcgatc atatctttat ccatctcccc acccagacgg acgcctgcat caaaacgttc
    14281 agaaacgaca tcggtcaaac cataatcaat ggtgagctga atatcaattt caggatgcga
    14341 tttcaggaat gtgcgcattg ctggtaacaa tatcgttttt gctgcatgtt ctacagtagt
    14401 aatacgtatt gtcccggatg ggcggttctg cagatcgctc agggatgcca tggctgaatc
    14461 tatgtcatgc aacatagggc caagaacaga caaaagatgc tcgcccgctt cagttggaac
    14521 aacgctgcgc gtggttcgcg tcagaagccg caatcccaat cgttcttcta tacgacgcac
    14581 tatctggctt aaagctgact gcgccatgct caggcgggct gctgcacgag tgaagctacg
    14641 ctcctctgca acgacgacaa acgccatcag atcagcgatt tcttcacgct tcattcagta
    14701 tctccatgca atctattaat catttaaatg ataggtctaa tcatgatttt gggtctaatc
    14761 aacttaatga tcaatatcta tagtgatatc accaaccgtt aaaacgaacc gacaactcca
    14821 tgaggaacgg aatgatgaat aataaagtca gcttcactaa cagcaataat ccaaccatct
    14881 ctttgtctgc agtgatctat ttccctccaa aatttgatga aacccgtcag tatcaggcaa
    14941 ttgtgttatc tcacccaggt gggggcgtta aagaacaaac ggccggaacc tatgccaaaa
    15001 aactggcgga aaagggattt gtcactattg cttatgacgc atcttatcaa ggtgaaagtg
    15061 gcggcgagcc gcgtcagtta gaaaacccat acattcgtac tgaagacatc agtgccgtga
    15121 ttgattacct gacaacgctt tcttatgtcg acaatacccg aattggtgcg atgggaattt
    15181 gtgccggtgc aggatataca gccaatgctg caattcagga tcgccgcatc aaggccatcg
    15241 gtaccgttag tgcggtcaat attggttcga tattccgtaa tggttgggaa aacaatgtga
    15301 aatctattga tgccctgcca tacgttgaag cgggttcaaa cgccagaacc agcgatatta
    15361 gcagcggaga atacgccatt atgccactgg caccaatgaa ggagtccgat gcgccgaacg
    15421 aagaactgcg tcaggcctgg gagtattacc acacccctcg cgcgcagtat ccaacagcac
    15481 cgggttacgc tactttgcgc agccttaacc agattattac ctatgatgct taccatatgg
    15541 cggaagtgta cctgactcag ccgacgcaga ttgtggcggg cagccaggca gggagcaaat
    15601 ggatgagtga cgacctgtac gatcgagcat caagccagga taaacgctat cacattgttg
    15661 aaggcgcaaa ccatatggat ctttatgacg gcaaagccta tgtggctgaa gcaatttcag
    15721 tattagctcc gttctttgag gaaactctgt aatgaaacat attcaaatcc gcaatagtga
    15781 tatggcctgg catattgctg ccaataatct gggataattt tcatgaaaaa tgtactgatt
    15841 cttggtgctg gcggtcagat agcccgccat gtgattaatc aactggcaga taagcaaacc
    15901 attaaacaaa ctttatttgc ccgtcagcca gcaaaaatcc acaaacccta tccaactaat
    15961 aaaatgcaaa caacttccgg caaaaaagtg atacaagatc gatgacatag cgttgaagaa
    16021 aaggatttga taatccgcaa aatttgcaca acactgcctg taatacttcc tgaaccagag
    16081 acgatcatga ccgtaacccg cccacgcgcc gaacgcggcg catttccgcc cggaacagaa
    16141 cattacggac gttcattatt gggcgcgccg ttaatctggt ttcctgcccc tgcagccagc
    16201 cgcgaaagtg gtttgattct ggctggcact cacggtgatg aaaactcttc ggtcgtcacg
    16261 ctctcctgtg ctctgcggac gttgacacct tctttgcgcc gtcatcatgt ggtgctgtgt
    16321 gtgaatcctg acggctgcca gttggggtta cgggccaatg ctaatggtgt ggatttaaac
    16381 agaaactttc cggcggcgaa ctggaaggaa ggtgaaaccg tttatcgctg gaacagcgcc
    16441 gctgaagaac gcgatgtcgt attactgaca ggtgacaaac ctggctccga acctgaaacc
    16501 caggcgctgt gccagcttat acaccgcatt caacctgcct gggtggtctc attccacgat
    16561 ccactggcct gtattgaaga tcccagacac agcgaattag gcgaatggct ggctcaggcg
    16621 tttgaattgc ctctggtaac cagcgtcggt tatgaaacgc ctggctcttt cggcagttgg
    16681 tgtgcagatc tgaacttgca ttgcatcacc gcagagtttc cgcccatctc ctccgacgaa
    16741 gccagcgaaa aatatctctt tgcgatggca aacttgctgc gctggcatcc taaagatgca
    16801 attcgcccgt cgtgaactga agcgccggtt ccacatctac cgccagccag gtcggtccgt
    16861 caagatcggc gaaactgacc tgcggcacca gcggtaaagc ggcgctaatg gcacgagagg
    16921 tacacaacat gcagcccagc atcagactga aaccttgtgc acgcgcttca gtcgccagcg
    16981 ccagcgcttc cgtcagaccc ccggttttat cgagcttaat attaaccatc tcatagcgcc
    17041 ctttcagcgc cttcaaattg ctacgagtat gacaactttc atcagcacaa atcggcaacg
    17101 gatgaataaa attctccagc gccgcatcgt cctgcgcagg aagcggttgt tcaagcatcg
    17161 caacgcctaa atccgccaat agctggcaac gcgccgccaa cccttctgca cgccaggatt
    17221 catttgcatc aacgatcagc gtcgcatcgg gcacagctgt gcgaattgcc accatccgct
    17281 cactgataag atggttatcc agcttcactt tcagtaattt cgcgcctgcc tgccagagtg
    17341 ttgatgcact attggccatc tgatcaggcg taccgatgac aaccgtctgt gcagtgataa
    17401 ctgtctcggg aagcgttatg ccgatcaaat cagccagcga ttgctgctgt cttcgcgcgg
    17461 ccagatccca caatgcacaa tccagcgcat tacgtgctgc gccggcaggg agaatttttt
    17521 gcaactcctc ccgtgtcagc cctttctcta gttgcggcac gacgctcata atttgcgcca
    17581 ttaccgaggc atcactttcc ccataacgcg gatacggcgt gcattcgccg gtgcctttaa
    17641 taccctcttc ttccagttca accaccacca cgcgcgcttc actgcgactt ccccgggcaa
    17701 tcacaaacgg ggtatgtaag ggccaggctt cctcgaatac cttaacggtt ctcatcttta
    17761 ctccttgttg tcgcggtggt ctgcggatta agcgcaaata gcgtttgctg tgttattgac
    17821 agttagcata aactaggtgt gacgttaact atatgtaaac aggaaagata atcatgtcac
    17881 aaaccgttca tttccagggc aacccggtta cagtcgccaa ttccatcccg caggcgggta
    17941 gcaaagcgca gacttttact ctcgtggcaa aagatctgtc tgacgtcacc ctcggtcagt
    18001 ttgcgggtaa acgcaaagtg ctgaacattt tcccgagtat tgataccggt gtttgcgccg
    18061 catcagtacg taagtttaac caactggcaa ctgagatcga caacaccgtt gtgctgtgta
    18121 tctctgccga tctgccgttc gcccagtctc gtttctgcgg cgcagaaggt ctgaacaacg
    18181 ttatcaccct ctccactttc cgtaacgctg aatttctgca agcttacggt gtggcaattg
    18241 ctgatggccc actgaaaggt ctggcagcgc gtgccgttgt ggttattgac gaaaatgaca
    18301 atgtgatttt cagccagctg gtggatgaaa tcaccaccga gccggattac gaagcagctc
    18361 tggctgtact gaaagcataa tttaatatgc ctgatggtgt tgcaccatca ggcatattcg
    18421 cgcttactct tcgttcttct tctgactcag accatattcc cgcaacttat tggcaatcgc
    18481 ggtatgtgaa acgccgagac gttttgccag tttgcgcgtg ctgggataat tgcgataaag
    18541 ctgggttaat accgagcgtt caaaacggct ggtgatttcg tccagcgaac cttccatcgc
    18601 atcttcgccc acggctaccg ttgcggcgtc ataatccggc aacaaaatat cctgtggacg
    18661 cagctcataa ccgtccagtt gtgtcagtgc gcgatagata gcgttcttta actgccgcac
    18721 atttcccggc cacgcataac gcgtaagtac agtattcagg tcagcggcca gtttcggacg
    18781 cggcacgccc tgctcgtcgg caaagcgggc gacgaacagc tcagttaacg gcatgatgtc
    18841 ctgcggacag tcacgtagcg gcggcagatt gagcgtcaac acgttcagac gataatagag
    18901 atcttcacgg aacatgcctt tttgcaccag ttcgaccaga ttcttctgcg tagcgcaaat
    18961 cacccgcaca tcgacatgca cctcatggtc ttcgccaacc cgacggaaag tgccatcatt
    19021 aaggaaacgc agtaatttcg cctgcatccg tggtgacatt tcccctattt catccaacag
    19081 caccgaacca ccgttcgcct gctcaaagaa tcctttcttc ccttccggag catgaccaaa
    19141 cagttcactc tcgaccgcat cttccggtat agacgcacag ttcagcgcca ggtaaggttt
    19201 gcccgctctg gggcttgcct gatggcaggc gtaggcaaag agatctttac ctgtacctgt
    19261 gtcacccgta atcagcagcg gcgcgcttag catcgccagt ttctgcgcct gttcgacaac
    19321 atgcttcatt ttcgggctga cggcgacaat ttgactgaag gcgctgacgt cctgggcggc
    19381 gacattttgc aactggcggc ccatacgaat cgttgatcgc aacatcacca ccgcaccggt
    19441 caggacgtgt tgatcatttt catcctgaag ataaacaggc gtaatctcca tcaggaaatt
    19501 ctgcccatta ataacgacat gctcgttatg cgaatcttgc ggttcgcttt ccagccaacg
    19561 taaaaaatta aagccgttaa tcaattgtgc ggcggtatgg ttgcgcaggc gatccaattt
    19621 ttgcccaaaa agctgacagc tcgccgggtt cgccatatcc actttgcttt tcatatcgac
    19681 agagagcaca ggttcaggca acgcctccag taacgcgctc aacgccagat gctcacgttc
    19741 ggaaggcatc cacgggacag tacgcacatc ggtaacaccc gcaatacggc gtatttcggc
    19801 catcagactg ctgaaactct caaactccag ttcagcaaaa ttgaggtaga ttcgcccaat
    19861 gggatcaatc tcaataccgc gtaaatcaat gcctcttagc acgagtagat cgagtaattc
    19921 gcgggtcaga ccgagtcggt cttcacaaaa gacttccaga cgcatgggaa ccttcacctg
    19981 aaaaaagaac aattaatatg atgatatgac actatttgga tagcaggaag gtttctgtca
    20041 acaatcattg acacaaagac ggaaaaacgg gcacttcggc gtaaagatat ccggtcagca
    20101 cccgatattg cattattttt cgctgggcgt tttgcctttt tgcagcgttt ctttcacctg
    20161 accgataagc tgacgacgga aatccccgag gcgaggtttg tcatcgtcaa tccacggcag
    20221 cgggcggcaa agctccatag ctttaatccc gagtcgtgcc gtcagaagtc ctgcaccaat
    20281 cccctgagct gcgcgggtag acaaacgagc agcgagatct tgcgacatcc agtccatccc
    20341 cacttcgcgc accagttcgc tggctccggc aaaagcgata ttcagcaata ccagcttaaa
    20401 cagacgcaaa cggctgtaat accccagttc aatgccatac agcgtggcga tgcgattaat
    20461 taaacgcaga ttgcgccagg cgataaacgc catatcgacc aacgccagcg ggctgaccgc
    20521 aatcatcaac gttgattccg ccgccgaacg gctgatttcg cgccgcgcct gggcatctaa
    20581 aactggctgg accaaatgcg catacaggct gaccacttca cggtcgtttt gcgtttcatg
    20641 gattgaggca taccagcgtt gcagcgccgg atgcgactga tcaatacccg cctgctgcgc
    20701 cagtttttcg caaaatgcgc ggcctttgcc cgtgccgtgg ctatgcaata aatcacgcgc
    20761 ttcgtcgcgt tcatgggcgc gctgtcgcaa gcgccataag cgccgccact ctgttaccac
    20821 agaacctacg ccagcgccga taatcaatgc cccagcggca catccaccca gcgccaccca
    20881 gtcctgggtt tgccaggcat tcattgtcca ctgtacaccc tgcccgacaa cgcttgcgcc
    20941 aaacagagcc agccctccca tcaccatttt gcgccacagg ctgcgtttcg gacgtaacgc
    21001 tgcgtccatt accgcttcga cttgcccctc ttcttcctgc gcttcgtcga gcgtggccgg
    21061 ggcaaaattt tgcgcctgat tttcgtcaaa ggtctgctgc gccctgaatt taggattctg
    21121 atcgacctcc agaggaccgt cgaaatcaat acgtggtttt aacggttcgg tcatcgcaat
    21181 ttatctccta ttaaaaattc cagcgcagca tcaagacgaa tatgcggtag tggtttgtcg
    21241 acatccatca cctgcggacg aaatgcctca aactggaagc cttgcttatc ccagaacgcc
    21301 tgaccaggca aacgtgcggg aacttcgcca ggataaacag tgagcggtgc gccatcgcta
    21361 agtcgattac cacgcagcgc cgggattttc tcaccgttaa catcaataat gccgctggtg
    21421 gtcgcctgaa ctgacgccag ccccaggcag tccatgctga tcccttcgaa cgccgcattt
    21481 tgccaggcat cctgaatcag ttgttgcagt aatgaaacca tattagcgtg ctgatcgatg
    21541 gtcacatggt ccgctttagt ggcagcaaac aatagcttat cgataaccgg cgaaaacaaa
    21601 cgccggaaca gggtacgctg cccgtagtga aaactttgca tcagctgcgt cagtgccaga
    21661 cgcatatcat taaatgcctg tggcccactg ttgagaggtt gcaggcaatc caccagcaca
    21721 atctggcggt caaagcgcag aaaatgattc ttatagaacc ccttcaccac cttctcgcag
    21781 taataattaa agcgctcgcg cagcattccg gcattggtat gcttatcggc ctgcgccagt
    21841 ttggactcgc cccaggtatc gacatccggc cacgggaaga attgcagcgc gggcgcacct
    21901 gccatatctc ccggcaagac aaagcgccca ggctgaataa agtgcagccc ctgctcttta
    21961 cagtggtgga gataatcggt ccacgcggcg gcaatgtccg ccagccggtt ttcgtcggca
    22021 ggcgctagcg ggtccagccc ttcgctcatc attcgccatt tcgccgacca ttctccgcgc
    22081 tgaccattga gtaagcccgt catctggcgc gaccagctta aatagtcctg cgccagcatc
    22141 ggcaggtcga gcaaccattc gccgggataa tccacaattt ccagatacag cgtggaggta
    22201 tccttaaagt ggcgtagcag cgaatcattc gatttaaaac gtagcgccag gcggatttca
    22261 ctgacgccgc gcgttggcgt tggccaggcg ggtggatcgc catataactg cgccagccct
    22321 tcgtcatagg tgaagcgcgg aatgccaaag tcacgctggg gaatgcgttt cacgcccagc
    22381 aggcgctctt cacgcaccgc acttaacagc ggcaaacgtg ctccggcgtg aatattaagc
    22441 aactgattaa ccatcgcggt gataaacgct gttttgccgc tgcggctaag tccggttaca
    22501 gcgaggcgca gatgtctgtc gacaccccga ttcaccagcg cattgagttc atttttaagt
    22561 cgcttcattg ctgtcctgtg ctgctctgaa gaccagaaaa aaaatcattc gtaaggatat
    22621 gaatgtgggg gccaggccat tgattatcaa ctgcccgtgt tgtcatcgac cggcgaactc
    22681 cataagatgt gcagcattca cgttcggacg gagttcctga cctatgtccc ctactattta
    22741 tgatattgcc agggttgcag gcgtatcaaa atccaccgta tcacgcgtgc tgaataagca
    22801 aactaatatc tccccggaag cgcgcgaaaa agtgttacgg gccattgaag aattacagta
    22861 tcagccaaac aagctggccc gcgcgctgac ctcttcgggt tttgatgcca ttatggtgat
    22921 ttctacccgt tcgaccaaaa ctacggcggg taatccgttt ttctctgaag ttctgcatgc
    22981 catcaccgcc aaagctgaag aagaaggttt cgacgtgata ttacaaacgt cgcacaatcc
    23041 ggcagaagat ctgcaaaaat gcgaaagcaa aattaagcag aaaatgatta aaggcattat
    23101 tatgctcagt tcgccagcgg atgagtcatt ttttgcccaa ctcgataaat atgatattcc
    23161 ggtggtggtg attggcaaag ttgaaggtca atatgcccat gtttattctg tcgataccga
    23221 taattttggc gacagcattg cgttgaccga tgcattaatt gaaagtgggc atcaaaatat
    23281 tgcctgcctg catgctccgc ttgatgtcca tgtttcggtt gatcgcgtta atggttataa
    23341 gcagagcctg gctgcgcata atattgcagt gcgtgatgaa tggattgttg atggcggtta
    23401 tacccatgaa actgcattaa aagcagcacg gcaattatta agccagtcac cgttgcctga
    23461 ggcggtgttt gccactgaca gcctgaaatt aatgagcatt tatcgtgcgg cagcagagaa
    23521 aaatattgct attccgcagc agttagcggt ggtgggttat agcaatgaaa cgctgtcatt
    23581 tattttaacg cctgcaccgg gcggcatcga tgttccgacg caggagttag gtcaacaaag
    23641 ctgcgagtta ttattccgct taatttctgg aaaaccgtca ccacagaata ttaccgttgc
    23701 cacgcatatg acgctgaaat aaataccagc taccttgcct gaatgccaga tgcgatgcta
    23761 gcgcatctta tccggcctac atttatagat cggataaagt actcgcgccg catccggcaa
    23821 tttagcccat tatcagaacg agtaatttac gccgacacct gcataatgga atttatcact
    23881 gtcgccttcg tcgtgatcct gccactcaaa cgcgtattcc agcgaaacgg aaagtccgtt
    23941 ctggaaatca taaccgtaaa ataaacctac acggttaaaa tcatggcctt cacgttcaat
    24001 atcatcctgc cagtcccagt tactccagcg atccagccca atgcgcgtat acggcgtcac
    24061 cgagtggttg ccgagcgtca gcggcaaata ggcgcgaatt tcttgcgtgg aaaactcacc
    24121 gttattgcgg ctgtcgtcca tattgaagcc gcgctcgaga taatagttca ctcgcaaggc
    24181 aaccgtttcg ttgaaggtat attgcagacc tgtttccgtt tcgacacggg tatcagcgta
    24241 accggtagtg ttcagatcgt tggcaaattt atacatcgac aaccaaccgt tgaaacgtaa
    24301 atcgtcagtc agtttcacat cccagtctgg cgcgattttc cagcgctgca tattcgccgt
    24361 gtctttaccc ggttcatcaa cgtagtgata accataatta cggaaaccgc cggtcaggcc
    24421 gaaactgaaa tcatcgcttt cgaggaactg ataatgcacc tccagctccg ggcgatcaaa
    24481 ccacgttcca cgtttacccg cgctataatc taccggccct tcctgataat aggccagcgc
    24541 aattctccac ggcccattgg cggcattaaa atagacagaa ggctccgcca gcccatccat
    24601 atcttcgcca taaccctcga cgttttctat ttcgtacatc gcaccgatat taaagtgcca
    24661 gtcgttcttt tcctcggcct gtgcgcaggc cattcccgca cacatcacca gtgcggtaca
    24721 gggtaataac tttttcatta ttgttccttg tattatcctg ggggaatgcc gtccccctgt
    24781 atttagcgaa ttgctatttc cgtttctgca tcaaagaaat gacatttcgt catatcaaaa
    24841 tgaatagtga tattttctcc tgcatgataa tcatttaacg caccagcacg gaccactaac
    24901 tcgtgccccc caaccgtggt gtagagcata aattccgcac cggttaattc tgccacgcta
    24961 attttggcgg aaatgttatt ttcctcttgc gcgtccggat gaatatcttc cgggcgtatt
    25021 cccatcacga tgggcttatg caaactttcc tgtgttttca gaaccgctaa tttctcttcg
    25081 ggaatggtta atttaagcgt ttccgtaacg aatttatcgc catcgatcgt gccgcgaata
    25141 aaattcatcg ctggtgatcc aataaatccg gcaacaaaca tattcgcggg ttggttataa
    25201 acggttttcg gcgcacctac ttgctgaaca atcccgtctt tcataatcac aatccgcgtc
    25261 gccatggtca tcgcttcggt ctgatcgtgg gtcacgtaga tcatggtggt gttcagtttc
    25321 tgatgcagct tgctgatctc tgcgcgcatt tgtacgcgca gcttggcatc aaggttagaa
    25381 agcggttcat ccattaaaaa cacgcccgct tcgcgcacaa tcgcccgccc gagcgccaca
    25441 cgctggcgtt gcccgccgga aagcgcgccc ggcttgcgtt tcaggtactc acgcaggccg
    25501 agaatttgcg ccgcccagtt cacccgctca tcaatcacct ctttggcgat tttttgcatc
    25561 ttcaggccaa acgccatgtt gtcgtagacc gtcatatgcg gatacagcgc gtagttctga
    25621 aacaccatcg ctatattgcg tgctttggct ggaacgtcat tcattcgttt gccgtcgatc
    25681 aacagatcgc cgccgctgat ctcctcaagc ccggcaatca tgcgcagggt ggtcgattta
    25741 ccgcagcccg acgggccgac aaatacgatg aactctttat cggcaatttc caggttgaag
    25801 tccttcacca catgcacctg gttatcgtag attttttgaa tatgttgtaa cgaaagctga
    25861 gccatgttga ttcctttgct atacgttttg ccagaaggcc gataaccgcg gccaggtgag
    25921 tgattccgtt gaaggcaaca gtaattgcgc cccggttaag cccgcgccga tccccaccga
    25981 gcgcataccg ctggcgttaa tggcgtcaat gcccgcctgc gcatcttcaa tgccgataca
    26041 tgcctgcggc ggcacgccca gccctgcaca ggcggcgaga aagatttccg ggtccggttt
    26101 cgagttttta agttgggaag catccgcgca gaaggtgaaa aactcgcgca gctccagcgc
    26161 cgctaaaatc gtcggcgcat tcagggagac agaagccagc ccaaccgaga tctgctgtgc
    26221 acggagatct gccagcaaag agcgaatgcc gggtagaaca gcgttgaccg tcaactcgcg
    26281 cagtgagtgg acgtaaagca tatttttgcg atacgccagt tgcgcccgct cctgcgggtt
    26341 aaagtcgccc tctttgcccc cgtgttgcag aatgcgccgc agagactcat cgcggctgat
    26401 cccttttagg gattcgttaa actgcgcatc aatgctgatg ccaatttcag cggcaatctg
    26461 ctgccacgcc tggaaatgca gatgcgcggt atcggtgatt acaccatcca gatcgaaaat
    26521 taccccttgc agtttcattc atcctcctga tgtgtggtag cggtcccatt gaagggcaaa
    26581 ataaaatcac ccaaacagaa aacagattct tcagccacgg atataagctg accgttcaaa
    26641 cgcagtgaaa cgggcgcaga agttcgaatc gcaatacgct gcgcgtcgag agtgacctgt
    26701 aattcgcagc cctgccagaa cagagggaaa gacaactgtt gccactgctc aggtaacgcc
    26761 ggattgagat gcaattcacc gtcacgcacg ctcaccccgg cgaaaccctg aatcgccccc
    26821 agccagatag cgccagttgc ggcagcgtgg ataccatcat cacaactatg cggatcagca
    26881 ccaagatcga tttcagtccc ctcgcgccag aactgataac tttgggtcag caggccacag
    26941 cgtgcggcaa caatgccgtg gattgcttta cttaatgacg agtcgtgaat agtgcgcggt
    27001 tcataaaatt gcagattggc aagacacgat gccgctgaga actgctccgg cagcatgtaa
    27061 ttgagcatca ccacatcagc ttgtttgagg atctgcatct cgttcacttc tgcgcgtgaa
    27121 taatccagca gtatggtttg cttccccgcc gccgctttgt atttcgccag attaatcgcc
    27181 ggcttagcca taaacgaatc atcctgcggc aaaacgccgt cgggctgaat ttctggcagc
    27241 cgcagttctt taaggaacat ttcggcacga tgaataaacg cgtcgtcgct acagccaaac
    27301 tggcgggcaa tactcagcgc ctgctggacg ttgtaatacg ccatatagct ggtgaaggcg
    27361 ttattattga catgttcggt atattcgtct ggcccaataa catcatgaat ttccagacgg
    27421 tcgttaaccc tcaccgcgcg gctaatccag aactttgcag tttccagaag tagcgccatg
    27481 ccttcatgag cgatgaaact ttcatccccc gtggtctgcc agtattgaat aaccgcccag
    27541 gcgatatcgg ccaccagatg atgttccgcc tgcgccgagg ccactttttg ccgcagcccg
    27601 gtgcgaatgt taatggcggc aaattccggc gtctcttctt cgccgctgcg cgcgctttcc
    27661 cacggaaata gcgcgccctg ccagccattg cgtcgcgctt tctcctgcgc gccagacaag
    27721 ttgtgccagc gataacgcag taaacttcgg gcaaccgtcg gatcgctaaa cagatgaaac
    27781 ggtagcaaaa atacttctgt atcccagaaa acgtggcctt tgtagccttc gccggttaag
    27841 ccttttgccg caatactgct gcgctcgtcg tgagccggcg tcatgatgcg cagatgataa
    27901 agcgcataat ctaacgcttg ctgatcgtgc gcatcgccgc catttaccgt gatacgacgt
    27961 ttctgccacc attgacgcca gttttctgtt gatgctgcaa gaagttggtc gtaactctgc
    28021 tgcgcgcaca ttgcaagctg gcgaagcgac gcgctgcccc actcgtctaa agcggcttgc
    28081 ctgtcatccc gccagtcgat ccacaccagt ttttgcaacg tcagcgtctc gcccgcacgc
    28141 agctgcgcgc tggtatgttg cagcaagcgg cgctctttgg cggtatagca ttgctgcaca
    28201 tcacctctca cctggcagca acaactgatg gccacatcac tgcgtccatc ctgggtggtg
    28261 tagatcccct gcatcagatg ctgaccaaac acccgcacct gggtttcgtc gagatgctgg
    28321 cgaccgtggt tggtttgtgt ggcgtcgata cccgttgata acagcactga agcctctgca
    28381 tccaacggcg taatgctgat ttccagcgcc atcagcgaaa gttgttctgc cgaaacaaag
    28441 cgacggctgg cgatggtgta acctgcgccg ttgctggtac gccagacaac gctacggcgt
    28501 aattctccac tggcaaagtc aagttcacgc tgccaggctt cgcgggataa cgagaaaacc
    28561 tcaccattta tggcaatctc catccccaag atatcaggca gattcaccag ttcgttgatt
    28621 tcaccttttc ccgcccgatg atacagcccc gccagataca tccctcgcgt ctggcgcgtg
    28681 taatcttctt catggctggc gcgaagccca agatagccgt tcccctgcgc catcagcgat
    28741 gcatacttgt tcagggtatg ctggctgaaa tggggttctg ataacgttac tggcctggtc
    28801 ataattccac acgcgtccct gtttctgcgg attgatataa cgccgccacc agttgctgga
    28861 tgatgtaccc ctgctcggcg tcggctatca tcacgggctt gccctgtacg tgattgataa
    28921 aggcttccat gctgcgcaaa tggcggttgt cgtctgccat ttcccgttgc atcagcgtca
    28981 ttaattcacc gttgttatcg gtgtagatat gtgctggaaa cagcgtcgca ccggctttat
    29041 caccacaaaa gctgacgttc ataatcgact gttcgcggat gttgagtgca aatgacgttt
    29101 ccagccacag aatgccgccg ttatgaaatt caatggtgcc aaacagcgaa tcttcgacgc
    29161 tgtaagttgc cggatcccac tcgccaaatt gaccacagct cttttgcgtg ccgatctttt
    29221 gaaaactatg cgcattcacg cttttcaccg ccggaaagcc cagcacatac atcgcagcat
    29281 ccagcatatg aatgccgatg tcgatcagcg ggccaccacc ctgcagttct ttattggtaa
    29341 agacacccca gccgggaacg ccgcagcgac gcagggcgcg ggcggtggta acgtaaatct
    29401 ctcccaaaac gccgttggtc acctgttcac gcagctgttg cgtatcgagc gcaaaacgat
    29461 ggtgaaagtc gtaggccagc accttgccca gtttgcgcgc ggtatcgcac atttcccgcg
    29521 cctgttgtgg cgtcatggcg ggcggttttt cgcacatcac atggcagcct gcttccagtg
    29581 ccatcagggt atgttcgtaa tgaaaacggt taggtgagca gacgctaacc acatcaggtt
    29641 tcaccgccag cagcatggcc tgcggatcgt cccacacgga tgcattaccg tatttatctg
    29701 ccagcgcctg cgcctgggaa aggcggctgt cacagacagc caccagttcc agatcgttgc
    29761 gggtgcagta gtacgaagca tgaaccttat ccgccacctg gcctgcgcct attatcgcga
    29821 cccgcagcgg agagcttgtc attgcacttt tcacaaagac ctcttagcag gtacgcaacc
    29881 aggccaacga atcacggtac gcctgggcag gatcttctgc ccggatacgc ccttcataca
    29941 ccacataacc ctgatagtta tcggcgcgca gctgttcaaa cagcgcgtgg aaatcgaggg
    30001 tgccgctgcc cggctggtaa cgatggttat cggcaatatg cacatgaccg agcaagtcac
    30061 ggttgtcgtg cagcgcctgc gccaggttat cttcttcgat gttcatgtga tagaaatcgc
    30121 cgataatctg cacatgttta agattgtttt cgacgatgta acgacgagca tcggcgaggg
    30181 tgttgatcat atgatcctga tagcggttta acggttcgag atacaccacg gttccggtac
    30241 gcgcggcgac ctgttccagt acgcgcaggg aatcactcac cattttgcgg tcgccgtcca
    30301 ggctacgcgg cgaggtcatc ggcggtaagc ggaaggtaaa catgccccac gctgccggaa
    30361 cgacgatacc tttacccccc acttctgcca gcgcttcgag aatgcgttcg atctgcttta
    30421 agccattaag acgacgctct tcgataaagt caccaatcca gccgtcatag ccgccgcagg
    30481 cggtggtcac tggtaaaccg gtttctttga tcgccgcttt gacttctccg atgttgttga
    30541 ccagcagttt gccgtcaatc tcaaaaccat cgaagcccat ctctttgata taacgaaatt
    30601 tctccagaat gttttccgga aagaacgcct gattctgtgt gccgattttc attttttcat
    30661 tcctttgaat taaaacgtaa cgcccatttt gatgctctgt tccggatgct gatcgacata
    30721 ctgcatgtag ctttcagggc tgttggcaaa ggtcactacc gggtcgatta aatcttcgca
    30781 attgagataa ccgttcatca gcagttccca gcaggtttct tcaatacgct tacggctcca
    30841 gcgcggataa tccgggttcg gttcgctgca cgcgcgagag aaaacaattt tggcgttatt
    30901 gaaatgcgct tcgcgtccga ggttaaaacc ttcagcaaat ggtttggcaa acgcgacata
    30961 ggagatggtg ccgccatagg ccagaccgcg cagcgccgat tgcagcgcgt cggcgtaacc
    31021 gctggtttcg ataatcacat cggcaccctg cttgccggtc agcgttttga tctctttgcc
    31081 tacgtcagtg ccaatggggt taaggcagaa atcagcaccg tggcgacggg caatatcaca
    31141 gcgatgggcg ataggatcga cgccaattac caccgatgcg ccagcgcgtt tcgccagttg
    31201 gatggcaatt tgaccgatcg cgccaagccc taccaccacg acaaaatccc ctacgcgtac
    31261 gttggcatcg cgcacgccgc tcatggcaaa ctgcgccggg tcgtaacaga cggcgttttt
    31321 ccaggagctg ccttgcggca ttttgcgcag cttgtagtta ttcactgcgt taatgatgac
    31381 cgtctcggag agcgggccgt agccgcatac gctgtcgccc accgcgtagt cggtaacgtc
    31441 gctgccgcac tcgataatgt cgccaaccac catgttgcca agctggaatt tgccaaactc
    31501 aatgccgcgc ggcgcatctg ccggacgcgg ggtgaacatc tgccactcgc cgttaaagtc
    31561 ttcatcgata aacgggctgg ctgcgcggaa gtcgaccact tccgttccgt gtttcggtgc
    31621 gccgaaacgc acgcggatct taacttcatt ggctaaaatc gcccgatctt catactcaac
    31681 cagcgcagca acacgcggtg ctgtggctac taactttttc atttaaaact ccttgtaaag
    31741 aaactggccg ctttagccct tcacgccacc ggcggtcaaa ccactcttaa taaaacgttc
    31801 cgaaagcgca tacataatca ccaccggcaa tgcggtcacc agcgaggccg ccatcatccg
    31861 tccccagata taatcaggcg tactgaacag cgcgttcagg cccaccggta aagtgaaatt
    31921 gctggcgctg gagaggaaaa tcgacgcaaa cagatagtcg ttccacgcca ccataaagca
    31981 gtagacgaac acggatatca gcccggacat cgccaacggc acggtgatgc ggaagataat
    32041 ttgcagacgg ttgaggccat ccatcatcgc cgcttcttcg atctcatcag ggatggtgtc
    32101 gaagtagctt ttcagcataa acacggcggt gggcagggtt tgcgtcacca tggtaatgat
    32161 cagcgccatc tcggtgtcgt aaataccaag cgcggtgatg attttgaaca gcggcaccac
    32221 cagcaaaatg ccagagaaca tatacaccgt gtaaaagctg gcgttgatgg tcatccggcc
    32281 tttaaagcgc aggcgggaaa gcgcgtaagc tccgagaatg ccgagaaata ccgccaccac
    32341 ggaggaaacc accgacacca ccatgctgtt acggaagtag tcgacaaacg ggaaaatcat
    32401 cgggttaaaa atgtcgacgt aatgctccag cgtccactgt tgcggcagca gcgtaggatg
    32461 cagcgatatc gcctctttcg cgcttttgaa cgaggtcatc agcatcacaa aaaacggaaa
    32521 cagcgtgatg atgagaaaca gcgccagccc gcagtaaaat ccgatacgac tgagtgtgcg
    32581 tttatttgtt gccattgagg ttcacccgtt tcctggtcag cagaatgaca gcgaaaataa
    32641 tgatgaagag caccaccgag atcgccgccg ctttccctaa gtcattaaag gcaaaggcgg
    32701 ttttgtagag atagacacca agaatatcga ccttggttgt cagcagataa acatccgcga
    32761 acatgtagaa catccagatg gtgcgcaggg tcaccaccgt cgccaggacc ggcataattg
    32821 cgggcagcgt gacgatgcga aaccgctgcc aggcattagc gccatccatc tctgccgctt
    32881 cgtacagcga tttgtcgatg gtctgcaaaa tcgccagaaa cgagataaag gcatacggga
    32941 agtagcgcca gatggcgaac agcaccacca gcacaaagct actgcccgga ttatcgaacc
    33001 acagcggtgc ctgctcatag agatgcagaa gatcgacgcc gaggtagttc acaatgccgt
    33061 agccgttgtt gaacatgtat ttccaggcaa acaccagcga aatggacggc gttacgtagg
    33121 agaggatcac cagcgaacgc gcggttttgc gcaggcggaa ctcgcggttg aaaaacatcg
    33181 ccactgccag cccgagcacg gtgctgcccg ccaccaccag cgcggtatac cagaccgtca
    33241 tccacagcga gtgccagaag ccgggatcgg agaggatacg cacatagtta ctcaccccaa
    33301 caaaggttga ctcgatgttg ggattgagcg gcagacgtaa aaaactgatt tcgatattcg
    33361 acaccattgg ccaggccacc agaccaccca gcagtaataa gctgggcgcg agaagcagca
    33421 gcgcaaaggg catatcggaa cgacctgaaa aaagcctgtt cattgcggat tcctgtcctg
    33481 ggtttagtgc tgttcgatca gttcatccag ctttttctgg ctcgcttgca gcgtgccagg
    33541 gagatcggct ttacccacgg tgacgttatg caccatggag ctcaccacgc cagaacccgt
    33601 cacatcaccc atgcgggtaa agtttttatc ccctactgca ccaaagacct gaatatttgg
    33661 cagttcaccg attagctgat tcggtagttc acccagcgcc ttaataacgt cgttgtcttt
    33721 ccaggtggcg gtagtgacaa ccgctttatt caccggcagc gcagcacctg gcgacatcat
    33781 cacccagtcg gcaatgttgt ctgcctgctc cataaaggtg acaaattttt cagctgcttc
    33841 cgtctcttcg gtcttttgcc cggcggtaat ggtcagcgag gtcaacatgc cgtagaccgc
    33901 agagtttttc tcggttggca ccacgaaacc gacgtttttc gggtcgcctt ctttaatcac
    33961 agccggaagg atataggtgg agtaaatcgc catcggcgcg gtgccgttca taaaggcgtc
    34021 tttcacttcc atgatgtcgt tagaacccgg catagtgttg gcagcaaggt cgcggtaata
    34081 ggtcagtgcc tgcatcatct ctggtgtatc aagggtgatt ttgccttcgg cgttaaagac
    34141 gttagcctgg ttggataacg caaactggga gaaggattgt tccgtcaaca cgctttctgc
    34201 tgtaggcagc gcaatgccgt attttttatt cgccgggtca ttcagtttct gtgcaacgtc
    34261 cagcagctgt tgccagtttt tcggctcctc aagccccgct tttgccagca catctttgcg
    34321 ataccagata ccgccaatcc aggcgctgac aggaacaccg gtccatgcgc taccatcttc
    34381 ggtacgcaca atacgcagta cgccatcgta aaacgcgcct tcaccaacgt tgctgatgac
    34441 tgtggcaacc gctttgcgat cgataagctg ctctttgtcc atcactttgg cgtagtcatg
    34501 gctggtttct atcacttccg gcagcgaacc gctacgtgaa agagtaatga ctttagtgtt
    34561 ataggcatct tcttccacgg gcacttgctt aacggtgatg ccagggtttt ctttttcaaa
    34621 acgggcaatc aatttactga taacggcctg gcgctcctgc tccaccgaag aatgcataaa
    34681 ttcgatggat acattcgttt tattttcttc tttacagcct gaaatcaggg cgcaggaaac
    34741 cagtgctgat aacagcacga tttttgattt aatcatgaga tgttcctttt tatttaatcc
    34801 acataacctg ccaggggcgc agcgttattt cattacccaa tatatcaact tcactaatca
    34861 gatcccgacc atgcagatta gtaatattta catgctgaat atttttactg acattaaaca
    34921 atccagtcag acaattacca tcagcgttac ttctttgaat acgcattacg gatgaattaa
    34981 tcgtatcaat ggtaaaatta ttatccggat gaaactcgtt atggctgcga cgaagtgtaa
    35041 ttaaacgcga caactcatga tataccgcat gccttaatgt agcttcatcg ttcagttctc
    35101 gggttatctc tttactgtga tattttttac ggttaatcgc acggttatat ccgagttttt
    35161 cgacacctgc gtaatcatta cgcgagccaa gaatactttg aatatatatc gctggcacac
    35221 cggggaaact taacaaaatc gcatgggcaa ggataaacct ggcgcaacgt tcttcatcgc
    35281 tactctcacg gcggcttaac gcatccatat aggtcacatt tatttcatac ggactgcgtg
    35341 taccgtcggg attatttttc cagtttacta atgcaccttc ctgctgtaac gcctcgacca
    35401 gctctaatat ttcgctttca ggcaacaagc cccgtagcgg gtttagcccg atgccatcgt
    35461 gagaggcgag gaagttaaac caggtggtgt tgctggaagg tagtgtcagg ttttgcgccc
    35521 acgcacaaag cgcctcaacg ttctgttttt gcaccgcatg cagcaccagt ggcggcagcg
    35581 agaactggta caccatatgt gcttcgtcat cgcctgcgcc aaagtaagca atgttgtctt
    35641 tatgcggaac attggtctcg gtaatgatca ctgtacctgg cgcaacgtta tcaataatcg
    35701 accgtaacag tttgataatc agatgtgttt tttccagatg gatgcagctt gttcccggct
    35761 ctttccacat aaagccaacg gcatccaggc ggacatactc agcacctttc gcaaggtaac
    35821 agagtaaaac atccaccatc gccagcaaca cttcagggct acggtaattc aggtcaattt
    35881 gatcgtcact aaaggtggtc cataaatggc gcgttgaatg atcgcgcatc tggaatggcg
    35941 ttaataacgg taacgcacgc gggcgagtga cggcgctgag atcggtttgc gggtcaacgg
    36001 caataaaaaa atcttcaaaa cctggatgct gttgtaaata gtttttaaac cattcacttt
    36061 ttgccgacat atggttgcag acaaaatcaa acattaaatg actgcattca ccgagttgct
    36121 gaatatcctg ccactccccc gcttcactgg cgacctgatg ataatcaatt accgaaaagc
    36181 catcatcaga tgaccatgga taaaacggca acaaatgaac atgtgaaaaa atgctttgca
    36241 gccattgatg gtaaaactga ttaaatgtgg gtaatggttt taaatcattg ctgtgaaatt
    36301 gatcggcata ggtaattaac acgacatcac tttcatccca gtgtttttta cgtcgctgtg
    36361 taattaatcg tttcgcactc tcaagacgcg ttacaagttt ctgtaaatga gttgcggtaa
    36421 atgttccacc gtagatttcg tccaggtaat ccgtaatttt ctgtttcatg ttgcctttcc
    36481 gtggtagcgg tcccatgaaa cgagagacta ctccgcagaa aataaactgt caattgagca
    36541 caagggtttt agtcacgcag gaaatcattt tttaccaggg aaaaagcgta tttgtgagct
    36601 gacgcaaata atctatgggg atgtaaataa ggtgtgacag aaaaaaaaac ggcgcataag
    36661 cgccgctcat ggtgaattct tttaaccttt gaccttcggc attgcgatgt ctttcaggcc
    36721 accggcgttc tcaacgtggg tatatcccat ctcgctaagg atctcttttg cttgccctga
    36781 ctggcgtccg gcattgcaat acactttcac ggtgtcgttt ttatccggaa cggcggtggc
    36841 aatgcgctct ttcacttcct tcaggggaat attgatggcc ccctgaacgt gctcttgctg
    36901 atactgctct ggaacacgaa catcgatcca gtgttcagcg gcgaaaacgg gcagtgaaaa
    36961 caccagtgcc agagcaagta agcctttttt aaacatgtaa gcgtccttct atggatgaaa
    37021 attgccatcc attatacgcc tgagatttaa caatttttgc gaaactcccc tcacctttta
    37081 taacgctgtg ccagtttatt agcagcccga cttaacagcg gttccagcgc cacagccagc
    37141 aacattttca gcggtcggcg agcaactgat tttatcgccc agcccgccac acccgccggg
    37201 ccatagcgca gtgcggtaag aagtaccagc ttgcctgcta atttgaaacc aggctttacc
    37261 ttttgcccgg cctgttgcca gcgagtattc ataactttcc tcacagttga cggaaacggc
    37321 tacgtaacgt gaaagtatcg gaagtgacat aacgttccat ctcgcgtaaa cgcgtttcac
    37381 ttgccgccag ttcacggtcg acttcatcca gcaattcgct gctggaaggt agctgctcac
    37441 caaaggccat gttgtccggc attggatcaa gcgcaaatga caaaatgatg taagcaacca
    37501 gggtaaacag cgccagaccg aagaaaatcg acagcaccac caggatacgc accagtttta
    37561 ccggtacatc aaaatagttg gcaatcccgg cgcagacgcc gcggaccatg ccctgctgtg
    37621 gaatacgcca taatttttta ttgagattaa tgcccgccat tagcgatccc tccagttcgg
    37681 atgttctgca tcaagaatag attccagcgc ctgaatacgt tcgcgcatcc gttttgcttc
    37741 atcagccagt tgcgctaatc gctgctgctc actttgcgac aattcactgc gaccagaacg
    37801 attgctgtaa tgcagccata accagatcgg taaaacaaac agcacaaaaa tggttaacgg
    37861 aatagccaga aatagcgcgc tcataagtac tccttagacg atgagcggcg gcgcgttcgg
    37921 acgccgcctg gatgttatta ttgattgtct tgcttcattt tggcttttaa ttgtgccagt
    37981 tgttcgctga ttgcatcatc ggctttcagt tcggcaaact gatcgtccag cgatttttgt
    38041 ttaccgaagc tgtggctttc tgcttccgct tccatctggt caatacgacg ttcgaaagat
    38101 tcgaaacgag ccattgcttc atccagtttg ccactgtcca gctgacgacg cacatcgcgc
    38161 gacgagtttg ccgcctgatg acgtaacatc aatgcctgct ggcgagcgcg tgtttcgctc
    38221 aatttgtttt ccagctcgcc aatctctttc ttcatgcgtg ccagcgtatc gtccaccagc
    38281 gtcacttcat gttccaggga cttaatcaga tcggtcagtt tctgtttttc aattaacgct
    38341 gcacgtgcca gatcctctct ctctttcagc agcgccagtt cggctttttc ctgccattca
    38401 acctcacgcg ccgacgcttg ttcaatacgg cgagtcagct gtttcttttc tgccaacgcg
    38461 cgcgccgaag tagaacgtac ttcaaccagt gtatcttcca tctcctggat catcagacga
    38521 accagtttct gtggatcttc cgctttctct aacagagcgt tgatgttggc attcacgatg
    38581 tcggcaaagc gagaaaaaat acccataatg ttgtcctctt gatttctgcg ttcaggattg
    38641 tcctgctgaa ctgttaatac aatttgcgtg ccaatttttt atctttttga tttataaaga
    38701 tctgattgaa gaatcaacag caacatgcca ggatgagtta gcgaattaca ctaacaagtg
    38761 gcgaatttca tcatggcaga atacaaagat aatttacttg gtgaggcgaa cagctttctc
    38821 gaagtgctgg aacaggtttc gcatctcgca ccgctggaca aaccggtgct catcatcggc
    38881 gaacgcggca ccggtaaaga gctgattgcc agccgcctgc attatctctc ctcccgttgg
    38941 caagggccgt ttatttccct taactgcgcg gcgttaaatg aaaatctgct ggattccgaa
    39001 ctgtttggtc acgaagcggg ggcgtttacc ggtgcgcaaa aacgtcatcc agggagattt
    39061 gaacgtgccg acggcggtac gctatttctt gatgaactcg ctacggcacc gatgatggtg
    39121 caggagaaat tattgcgcgt gattgagtac ggtgaactgg agcgcgttgg cggcagccag
    39181 ccattgcagg tgaatgtgcg gttggtatgc gcgacgaatg ccgatctccc ggcgatggtc
    39241 aatgaaggca cttttcgcgc tgacctgctc gaccgactgg cttttgatgt tgtacaactg
    39301 ccaccactgc gcgagcgcga aagcgacata atgttgatgg cagaatactt tgccatccag
    39361 atgtgtcggg aaatcaagct gcctctgttc ccggggttta cggagcgcgc cagagaaaca
    39421 ttgctgaatt atcgttggcc gggaaatatt cgtgaattga aaaacgtggt ggaacgttca
    39481 gtgtatcgcc acggcaccag cgattatccg cttgatgaca tcattattga tccctttaaa
    39541 cggcgtccgc ctgaagacgc tatcgccgtt tcagaaacca cctcgcttcc aacactgccg
    39601 ctggatttac gtgagtttca gatgcagcag gaaaaagagt tgctgcaact cagtttgcaa
    39661 caagggaaat ataaccagaa gcgcgcggct gaattactgg ggttaactta tcatcagttc
    39721 cgcgcgttgt tgaaaaagca ccagatttag cgaagttgag caatacaact tgccggatgc
    39781 ggcgtgaatg ctttattcgg catacataat caatacgtcg tttgcaggcc tgataagcgc
    39841 agcgcatcag acattattgc gttgggctat taatcgctca gcgcatcctg caaaattttc
    39901 attgccgcat cgaattgcgc atccgggatg gtcagcggat acaggaagcg aatcacgttg
    39961 ccgtatgcgc cacaggtcag caggagcagc ccctgcgcca gcgcgcgttg ctggattttc
    40021 tgtgcaatcg ccgctgacgg ctcgcccgtt tgcggatcgt taaactctac cgcaatcatc
    40081 gaccccaggc cgcgtaccgc agcaatggcc ggaacgcttt ctttggcatc aatcaacgtg
    40141 tttttgagac gctggcccag ttgattcgcg cgttcgcaga gtgattcttt gtcgataatg
    40201 ttgagcaccg cgtgcgcggc agccaccgcc agcgggttac cggcgtaggt gccgccaagc
    40261 ccgcccggcg cgggtgcgtc cataatattc gcgttaccga ccacgcccga aagcggcatc
    40321 ccgcccgcga ggcttttcgc catcgtcatt aaatccggct tatcggcgta atgatccatg
    40381 gcaaacagct taccggtacg cgcaaagccg ctttgcactt catcagcaat catcacaata
    40441 ccgtgctcgt cgcacaggcg gcgaatagcg gcaaccagct cttttggcgc aacgttgaaa
    40501 ccgccctcgc cctgcaccgg ttcgaaaata atcgccgcca cctgcttcgc ttcgatgtct
    40561 gatttaaaca agcgttcgat ggcgtcgagg gagtcctgtg ttgaaatgcc gtgtaaatct
    40621 gacggataag gtacgtgata caccgaacca gggaacgggc cgaagccgat tttgtacggc
    40681 gcaacttttc cggtcagcgc catggtcata tacgtacgac cgtgaaagcc gccgctaaac
    40741 gcaatcacgc cagggcgtcc ggtatgggcg cgagcaattt tcaccgcgtt ttccaccgct
    40801 tccgcaccgg tggtgaagaa cgcggttttg gcctgcccgc tcaccggggc aagggcgttg
    40861 attttctccg ccagggtgac gtagctttca tacggcacaa tctgatacgc ggtgtgggta
    40921 aactgttgca gttgctgctc caccgccgcg accagatcag ggtggcgatg tccggtattc
    40981 agcaccgcaa tgcctgcggc gaaatcgatg tactcgttgc cctcaacatc cttcagcgtg
    41041 gcgttttcag ccgactgggc gaagaagtta cacatcacgc caaccccgcg cggagtggca
    41101 gaaagacgac gctgatggaa ttcattgttg ctcatgtttc acaccttttg actcttcacg
    41161 gttaatcgga aattaaacgc ccagacgatc gcgcaggctg taatacgccg cgcccatcgc
    41221 ggtaaacggc acacgcagcg tgcgcccgcc ggggaacggg taatgcggca gattggcgaa
    41281 ggcatcgaaa cgttcggcgt cgccgcgcag cagttcggca atcaaacgtc cggctagatg
    41341 agtacaggtc acgccgtggc cgctgtagcc ctgcatgtaa tagatgttgg tatcgaggcg
    41401 accaaactgc ggcatacgcg acagggtcag caggaagttg cccgtccagc ggtaatcaat
    41461 tttcacgccc ttcagctgcg ggaaggtttt cagcagtttc ggcaccacaa ggcgctcaac
    41521 gtcatccggg tcgcgcgcgc cgtagaccac gccgccgccg tacagcaggc ggttgtcggc
    41581 ggtaagacgg tagtaatcaa gcagatagtt acagtcttcc acacagtagt ttttcgggat
    41641 cagcgagcgg gctaaatctt ccgacagccg ttcggtggtg atcacctgcg tgccgcacgg
    41701 catgctgcgt ttcgccagtt ccggctctac tttatcgccc agatacgcat tcccggcgac
    41761 aatcacatac ttcgccgtca cctgaccttt ggcagttcgc acaacggctg gcgtggtgtg
    41821 ctggatctgc gtcacggcag aaagttcata cacgcgcccg ccgttgaggc ggatggcgtc
    41881 cgcttcgcca atggcaaggt ttagcggatg aatatgccca ccgctgtgat ccagcagcgc
    41941 accggtatag cgatcgctgg ctacttcacg gcgaatggcg ttggcgtcca gcaattccag
    42001 ctgtttattg ccgtagcgtt cccagttctc tttctgctct tcaagtgtgg cgagctgttt
    42061 atcattcatc gccacaaaca ggccgccggg gcggtagtcg cagtcaatct gataacgttt
    42121 gatacgttcg cggatgatct caccaccttc gaacatcatg ctgccgagca tacgggcggt
    42181 gtccatgccg tagctttttt cgatcacgtc gatgtcgcgg ctgtaggagt tcacaagctg
    42241 tccgccattg cgcccgcttg cgccaaagcc gatgcgtgag gcttcgagaa ccactacgtc
    42301 aaagcccgct tccgccagat gcagcgcgga ggagagcccg gtatagccgc cgccaaccac
    42361 gcaaacgtcg caggtgattg actcattcag cgtgtcgaat ggtgcatatt tattcgcact
    42421 ggcggcgtag taactgctgg tatgttcggt catttcaggc ctccaggctt atccagatgg
    42481 ttttcagttc agtgaatttt tcaagggcat gcagggattt gtcgcgaccg ttgccgctct
    42541 gcttatagcc gccaaacggc acggtcatat cgccgtcgtt gtagttattg acgaagacgg
    42601 aaccggcttt caggcgtcgg ctcatgcggt gcgcgcggga gaggtcgcgc gtccataccg
    42661 ccgcgccaag gccgtactgg ctgtcgttgg caagctgtag cgcctgttct tctgatgtga
    42721 aacgcgtgac caccagcacc ggaccgaaaa tctcttcgcg acttaaggac gcattcgggt
    42781 ccacatccac aaagatggtc gggccgatgg cggcagccag cccggcgtta cggccatcca
    42841 acaacagttg ccctttgctt tcgccttccc gaataaagct atggaccgag tcggcgtggg
    42901 cgcagtcgat taaggtgccc atggtggttg cgggatcaag tggatggccc ggctgccagt
    42961 tttgcgcctg ctgttttaac agggctaaga attcatcggc gatgctctct tccagcaaca
    43021 ggcgcgttcc ggcgatgcac acctgtccct ggttgtagaa aatgcctgct gcggtggcgc
    43081 ttgccgcctg ttgcaaatcc gggcagtcag cgaaaacgat gttggcgctt ttgccgcccg
    43141 cttccagcca gacgcgtttc atgttgctgt cgcccgcatc tttcagcagc tgtttcccgg
    43201 tacgggttga accggtaaag gcaatggcgt cgatatcgtt atgacgcgac agcgcctgcc
    43261 cggcttcatg accaaaaccc gtcaccacgt tcaacacacc atccggcaag cctgcttctt
    43321 tcgccagccc cgcgagacga atcgcactga gcggtgattt ttcagacggt tttagaatca
    43381 cgctgtttcc cgccgccagc gccgggccga gtttccagca agtcagcaac agcgggaagt
    43441 tccacggcac gatggcggca atcacgccga ccggttcacg cacgatcatc gccagctcat
    43501 ggctactggt ggtcgccact tcgccataca ctttgtcgat cgcttcggcg taccagcgaa
    43561 tggcgcgcgc cgcgccggga atatcatcac gcagactgtg acgaatcggt ttgccggtgt
    43621 cgagagtttc cagcagtgcc agctcttcgg cgtgggcttc cattaaatcg gcgagtttat
    43681 tcagtaccgc tttacgttta gccggagaag agagtgacca gtcgccgcgt tcaaatacgc
    43741 cgcgtgctgc gctcatcgca cggtcgatat cgacgctctt gccgcgggca attttcgcca
    43801 gcggtgcctg ggtgaccgga tcaacggttt caaaggcttc attttccgcc gcagcagtat
    43861 attcaccgtt aataaataag cggttttcaa tggcgagact taacgcttta tcctgccagt
    43921 aagccagatg atgaaaattc attatgactc ctgtttcacg tctatcagat atatgcagtt
    43981 tgtgaacgtc agggcgcaga gatccccggg ccgtatgccc gtttatttct ggcgacattc
    44041 tttatataca cttcatcctt caagccgcct ctgccttggc tgcgttcgct cccccgaatc
    44101 acttacctga gtaagctcat cgggattcgc tcacttgccg ccttgatgca acttgaatga
    44161 ttttgtgtat agattgccgg gcgcattgcg cttacccggc ttacagaaca aaaagattaa
    44221 aacgtggtgg gcgtatgggc gctgataatt cggcaaatac ctgccgacgt attactgaaa
    44281 ctgtgcggga tgccggtatt aatggcataa ctttgccccg cgacgaggtg gtaatcctga
    44341 ccattaatcg tcagaacaat ttcaccttcc agtacagtgc ctatttcctc accctgatgc
    44401 ttaattcttt ccccagtggt tgtgcccggc tggtacgttt caaagatcat cgccagcgtg
    44461 cgattcgggt taccgttatg aaccagcttc attgacacac cctgactacc catctcaatt
    44521 aagtcgtcct gattaatgac gacctgcggc tcatcaggtt tttccggctc ggaaaagaat
    44581 tccgagagtg acagaccata caccttcagc agcttttgca gcgtactgat ggcagggctg
    44641 actttatctt gttctatcgt actgatagca ctgtgagtca gcccggagag ttcggcggca
    44701 cgacgttgtg aaagcccctg ctgctggcgg atttccgaca agcgttttcc tggcgccagt
    44761 ccctcatcac tcatatttgc atttccttaa actgtagtgg tcagagtcgc tgtttttcag
    44821 cgatatggtg ctgacaagcg gtgataaagc cctcgaacaa tatacgcgaa agcgcgtact
    44881 cgctactgtt ccattccggg tgccactgta cgcccagcgc aaaaggatga ttgatgacgc
    44941 taaccgcctc aactaagcca tccggcgagc gagcttcaac acgcaaccgt gggctaacga
    45001 ccttcgcccc ttgtccatgt agagagttta cccaaaagtt gctacattca ggtaacaacg
    45061 cagacagtaa tcccccctct tcaacctgaa cttcatgcga cggtgcatat tgctgttcca
    45121 ccggcagttc gggatcttcc cgatgttcca gcaattcagg ctgttcgcac agcttgcgat
    45181 gcaacgaacc accggttgcc accaccagtt cttgtaaacc ccggcagatg gcgaaaatgg
    45241 ggatgcgcct ttcgagtgcg gcattaatta tcgccatgct cagaagatca cgcccgggat
    45301 cggcgtcagg ctcatcgccg ttttcaccat ataggtgcgg ctgcacattg ctgggactac
    45361 caggaagata aatgccatcg agtttcggca aaagttgttc aagtaatgac ggttccgcca
    45421 gcgcatgtgg tagcgcaata ggcaagccgc ctgcatggat gatggcattc aggtactttt
    45481 cttgcagagt ctgggtcgca tgacccttaa gcctgttcct gcacattacg acaccgataa
    45541 ccggattgtt cattatattt tccatgctca atctcacaaa gtggactaaa ttatcgccat
    45601 tactgcgctt taaatgacct ttatgttcaa tattttttca atctagcagt gggttttcat
    45661 ttttgcaaac tcaatttaac atttgacaaa catttagttt gcatacagat tcgaatggtg
    45721 gtcattatat tttacgcttt gataacgagc ggaaaacaaa ccaaaggcga agaatcatgg
    45781 aaaccaatat cgttgaagta gagaactttg ttcagcagtc agaagagagg cggggtagcg
    45841 cctttacgca ggaagtgaaa cgctacctgg agcgctaccc gaatacgcaa tatgttgatg
    45901 ttttacttac cgatttaaat ggttgcttcc gtggaaagcg tattcctgtt tcaagcctga
    45961 agaagctcga gaaagggtgt tatttcccgg cctcggtatt tgcaatggat attctgggca
    46021 acgtagtaga agaagcaggt ctgggtcagg aaatgggcga gccggatcgt acctgtgttc
    46081 ctgttctcgg ttccttaact ccttctgccg ccgatccaga gtttatcggt cagatgctcc
    46141 tgaccatggt cgatgaagat ggcgctccct ttgacgttga gccgcggaac gttcttaacc
    46201 gcctgtggca gcagctgcgc cagcgcggat tgttcccggt cgtagcggta gagctggagt
    46261 tctatttact ggatcgccag cgcgacgctg aagggtatct gcaaccgccc tgcgcgcctg
    46321 gcaccgatga ccgcaataca caaagccagg tttactccgt tgataacctc aaccacttcg
    46381 ccgacgtgct caatgatatt gatgaactgg cgcagttaca gctgattccg gcagatggcg
    46441 cggtcgctga ggcctcgccg ggtcagtttg aaatcaacct ttaccatact gataacgtgc
    46501 tggaagcctg cgatgatgcg ctggcactaa aacgcctggt gcgtctgatg gcagaaaagc
    46561 ataagatgca cgccactttt atggcgaagc cgtatgaaga gcacgcgggc agcggaatgc
    46621 atatccatat cagtatgcaa aataatcgtg gcgagaacgt gctttctgac gcggaaggcg
    46681 aagattcgcc gctgctgaaa aagatgctcg ccgggatgat tgacctgatg ccgtcgtcga
    46741 tggcgttgct ggcaccaaac gtgaactcgt atcgccgctt ccagccggga atgtatgtgc
    46801 cgacgcaggc gtcgtggggc cataacaacc gcaccgtcgc cctgcgtatt ccgtgcggcg
    46861 accgtcataa tcaccgcgtg gaatatcgcg tggcgggtgc cgatgccaac ccatatctgg
    46921 tgatggcagc gatttttgcc ggtattttgc atggccttga taacgagctg ccgttgcagg
    46981 aagaagtcga aggcaacggg ctggaacagg aaggcttacc ctttccgatt cgccagagcg
    47041 atgccctggg tgagtttatc gagaatgatc acctgcgccg ctatttaggc gaacgcttct
    47101 gccatgtcta tcacgcctgt aaaaatgatg agctgttgca gtttgagcgc ctcatcacag
    47161 aaacagaaat tgagtggatg ttgaaaaacg cgtaataccc cttgcggggt tgtttcatcg
    47221 gcctgagcgg agccaggcct gacatttgct ggtaatccag acatttcccg gatgtcgcgt
    47281 tatggagcgc gggcggcaac gggcttccgt taacgattaa gactgtgacg aggaaatgag
    47341 atgatgccga tgattaaatc cccgcatggc gagggaggct gcgtatgcgc ccctcctgct
    47401 actgactgga ctccgccccc tttgcttccc ttgctaaaca ggtttgattt caggtcgaca
    47461 cgaccgcaaa ccttattacg caggggaggc agcaagtatg gctattaatt caccactgaa
    47521 tattgctgcg caacccggca aaacccgtct gcgaaaatca ctgaaattgt ggcaggtggt
    47581 gatgatgggt ctggcctatc tcacgccgat gaccgtattt gatacttttg gtattgtctc
    47641 cggcattagc gacggtcacg ttccggcgtc ctatttgctg gcgctggcgg gtgtgctgtt
    47701 taccgctatc agctacggca aactggttcg ccagtttccg gaggccggtt cggcctatac
    47761 ctacgcgcaa aagtcgatta acccgcacgt cggatttatg gtcggctggt catcgctgct
    47821 ggattatctc tttttgccga tgattaacgt cttgttggcg aaaatctatc tctccgccct
    47881 cttcccggaa gtgccgccgt gggtgtgggt ggtaaccttc gtcgccattt taaccgccgc
    47941 gaatctgaag agcgtcaacc tggtcgctaa cttcaatacc ctgtttgtac tggtgcaaat
    48001 ctccatcatg gtggtgttta tcttcctggt agttcaggga ctgcataaag gagaaggcgt
    48061 tggcaccgtc tggtcacttc agccgtttat cagcgagaac gcgcacctga tcccgattat
    48121 taccggggcg acgattgtct gtttctcctt cctcggtttc gatgcggtga ccacgctttc
    48181 ggaagagacg ccggacgccg cacgcgtgat cccgaaagcc atcttcctga cggcggtcta
    48241 cggtggcgtt atctttatcg cggcgtcgtt ctttatgcag ctgttctttc ccgatatcag
    48301 ccgctttaaa gatccggatg ccgcactgcc tgaaattgcg ctgtacgtcg gcggcaagct
    48361 cttccagtcg attttcctct gcaccacgtt tgtgaacacg ttagcctctg gcctggcttc
    48421 acatgccagc gtgtcgcgtc tgctgtatgt gatggggcgt gacaatgtgt ttccggagcg
    48481 cgtgtttggc tatgtgcacc caaaatggcg gactccggca ctcaacgtca ttatggtcgg
    48541 gattgtcgcg ttgtcggcgc tgttcttcga tttagttacc gccacagcgt taattaactt
    48601 cggtgctctg gtggcgttta ccttcgtgaa tctgtcggtg tttaatcatt tctggcggcg
    48661 taaaggaatg aataaaagct ggaaggatca cttccactat ttgctgatgc cgctggttgg
    48721 cgcgctgacg gtgggtgtgc tgtgggttaa cctcgagtca acgtcactga cactcggtct
    48781 ggtatgggct tcgttaggcg gcgcatattt atggtatctg atccgccgct atcgcaaagt
    48841 gccgttgtat gatggtgaca gaacgccggt gagtgaaacg taatagtcgg atgcgcggcg
    48901 cattatcctg cctgagggta acgcgccgcg ccattaacta taaaaagatg tatgacccgg
    48961 atcacgagtg ctatcatccg cccttatgct tagcgcatta accccagggg caaataatga
    49021 accacgatat cccgctaaaa tattttgata ttgccgatga gtacgcgacc gaatgcgcag
    49081 agcctgtcgc agaggctgaa cgcacaccgc tggcccacta cttccagtta ctgctcaccc
    49141 gtttgatgaa caatgaagag atcagcgaag aagcccaaca tgaaatggct gctgaagcgg
    49201 ggattaatcc cgtacgcatt gatgagatcg cagagttttt gaatcaatgg ggtaatgagt
    49261 aatgatttaa ttgcagacga tcggtcagta tcgttgtccg gataaagcgt tcacgccgca
    49321 tctggctaac aatgacacgc actgcagcgt gctttaatgg gtttctcacg atcgtaccgc
    49381 tctgctcctc gctaagttgt tctgtgagtt atagttatag agaaatcacg ggtacgaatg
    49441 ttgaacagat ggcgacgtca cctgttcaac gaccaaccac acggccctca ttacgccccc
    49501 tggacacaaa cggtaatggc aaatgtcatt aaatattagt aagatagcct ctttacataa
    49561 aatcccttaa tattatgcgc caggtattat cgtctctttt ggtgattgct ggacttgtga
    49621 gtggtcaggc aatcgccgcg cctgaatctc ccccgcatgc tgatatccgc gacagcggtt
    49681 ttgtctattg cgtcagcggg caagtcaaca cctttaaccc atccaaagcg agcagtgggt
    49741 taattgtcga tacccttgcc gcccagtttt atgatcgact gctggatgtc gatccctata
    49801 cctatcgcct gatgccggaa cttgccgaaa gctgggaagt actcgacaac ggcgcgacct
    49861 atcgcttcca cctgcgtcgc gatgttccgt ttcaaaaaac cgactggttt actcccactc
    49921 gtaaaatgaa tgccgacgat gtggtgttta ccttccagcg aatttttgac cgcaacaacc
    49981 cgtggcataa cgtcaacggc agcaacttcc cctacttcga cagcctgcaa tttgccgata
    50041 acgtgaaaag cgtccgcaaa ctggataatc ataccgttga gttccgactc gcccagccgg
    50101 atgcttcttt tttgtggcac ctcgcaaccc attatgcttc ggtcatgtcg gcagaatatg
    50161 cccggaagtt agagaaagaa gatcgccagg agcaactcga ccgtcaaccg gtcggcaccg
    50221 gtccgtatca gttgtcggaa taccgcgccg ggcaatttat tcgcctacaa cgtcatgatg
    50281 acttctggcg cggtaaaccg ttaatgccgc aggtagtggt ggatttaggc tccggcggca
    50341 ccggacgtct gtcgaaactc ctgaccgggg aatgcgacgt tctggcctgg cctgctgcca
    50401 gccagctatc cattttgcgt gacgacccgc gcttgcgttt aacgctgcgt cctgggatga
    50461 acgtcgccta tctggcattt aacaccgcca aaccgccgct aaataatccc gctgtccgcc
    50521 atgcgctggc actggcgatt aataaccagc gcctgatgca atccatctat tatggtacgg
    50581 ctgaaacggc ggcctctatt ttaccgcgcg cctcgtgggc ctatgacaac gaggctaaaa
    50641 ttactgaata caatccggcg aaatcgcgcg aacagttgaa gtcgttgggg ctggaaaatt
    50701 taacgctgaa actgtgggtg cccacacgtt cgcaggcgtg gaaccccagt ccactgaaaa
    50761 ctgccgaact gattcaggcg gatatggcgc aggttggcgt aaaagtggtg attgtgccgg
    50821 tagaaggtcg ctttcaggag gcgcggttga tggatatgag ccatgatctg acgttatccg
    50881 gttgggcgac ggacagtaac gacccggaca gtttcttccg tccgttactg agctgcgcgg
    50941 caattcattc gcagaccaac ctcgcccact ggtgcgatcc gaaattcgac agcgtattgc
    51001 gtaaggcgct ctcttcgcag cagctggcgg cgcgtattga agcctatgac gaagcgcaga
    51061 gtattctggc gcaggaattg cccattttgc cgctggcgtc gtcattgcgt ttgcaggcct
    51121 atcggtacga tatcaaaggt ctggtactta gcccgtttgg taacgcctcc tttgctgggg
    51181 tgtatcgcga gaaacaggat gaggtgaaaa aaccatgatt atcttcacct tacgccgcat
    51241 tttgttattg attgtcacct tgttcctgct gaccttcgtt ggcttcagct tgagctattt
    51301 cacccctcat gcgccgttac aaggcgcgtc actgtggaat gcctgggtgt tctggtttaa
    51361 cggcctgatc cactgggatt ttggtgtttc cagcattaac ggtcaaccga ttgccgaaca
    51421 gttaaaagag gtcttcccgg cgacgatgga actgtgcatc ctcgccttcg gttttgcgct
    51481 gattgttggc atccccgtgg ggatgattgc cgggattacg cgccataagt ggcaggataa
    51541 cttgatcaac gccatcgcct tactgggctt ttcaatcccg gtgttctggc tggcgcttct
    51601 gttgacgctg ttttgttcac tcacgctagg ttggttgccc gtttcagggc gtttcgatct
    51661 gctctacgaa gtgaaaccga ttaccggttt tgcgttgatt gatgcctggc tttcggactc
    51721 accatggcgg gatgaaatga tcatgagcgc aatccgccat atgatattgc ccgtgatcac
    51781 cctgtcggtt gcgccaacaa ctgaagtgat ccgcctgatg cgtatcagca ctatcgaagt
    51841 gtatgaccag aactatgtaa aagcggcggc gacccgcggt ttgtcgcgct ttactatttt
    51901 gcgtcgccac gttctgcata acgcgttacc gccggttatt cctcgcctgg gcttacagtt
    51961 ttccaccatg ctgacgctgg cgatgatcac cgaaatggtt tttagctggc cgggtttagg
    52021 gcgctggtta attaacgcca tccgccagca ggattacgca gccatttccg ccggagtgat
    52081 ggtgtgtggc tcactggtca ttattgttaa cgtgatttct gatattttgg gtgccatggc
    52141 taaccctctg aaacataagg aatggtatgc cttacgatag cgtatacagc gaaaagcgcc
    52201 cgccgggcac gctgcgtacc gcctggcgca aattttatag tgacgcctct gcgatggtcg
    52261 gcctgtacgg ctgcgcgggg ctggctgtac tgtgtatttt tggcggctgg tttgcgcctt
    52321 acggcatcga ccagcaattt ctcggttatc aattattgcc gccgtcatgg tcgcgctatg
    52381 gcgaagtttc tttcttcctg gggactgacg acctcggacg cgatgtttta agccgtttac
    52441 tgagcggagc tgcgccaacc gtgggtggcg catttgtggt gacgcttgcc gcgacgatct
    52501 gtggcctggt actgggcacc ttcgccgggg cgacacacgg cctccgctca gcggtgctta
    52561 accatattct ggatacctta ctggcgatcc cttcgctgct gttggcaatt atcgttgtag
    52621 cgtttgccgg accgagtttg tcccacgcta tgtttgctgt ctggctggca ttgctgccgc
    52681 gtatggtacg ttcgatttac agcatggtgc atgacgaact ggaaaaagag tacgttatcg
    52741 ccgcccgtct ggatggcgca tcaacgctga atattctctg gtttgctgtg atgccaaaca
    52801 tcaccgccgg gctggtcacc gagatcaccc gcgcactgtc gatggcaatt ctcgatatcg
    52861 ccgcgctggg ctttctcgat ctcggcgcac aactcccctc gcctgaatgg ggagcgatgc
    52921 tcggtgatgc gctggaactg atttatgtcg ccccgtggac tgtcatgctg ccaggtgcgg
    52981 caattatgat tagcgtgttg ttggttaacc tccttggcga tggcgttcgt cgtgcgatta
    53041 ttgcgggggt ggaataatgc cattactcga tattcgtaac ctgaccattg aatttaaaac
    53101 cggtgatgag tgggttaaag ccgtcgaccg ggtaagtatg accttaaccg aaggtgaaat
    53161 ccgcggtctt gttggtgaat ccggttccgg caagagtttg attgcgaaag cgatttgtgg
    53221 ggtgaataaa gataactggc gtgttactgc tgaccgtatg cgttttgatg atatcgattt
    53281 gctgcgtctc tccgcacgcg aacggcgcaa actggttggc cataacgtgt cgatgatttt
    53341 ccaggaaccg cagtcgtgtc ttgacccttc agaacgtgtg ggccgccagt tgatgcaaaa
    53401 catcccagcc tggacctata aaggccgttg gtggcagcgt tttggctggc gcaaacgccg
    53461 tgccattgaa ctgctgcacc gcgtggggat taaagatcac aaagatgcga tgcgcagttt
    53521 tccctatgag ttgaccgaag gtgaatgtca gaaagtgatg atagccattg cactggcgaa
    53581 tcaaccgcgt ctgctgattg ctgacgaacc gaccaactca atggagccaa caacccaggc
    53641 gcaaatcttt cgcctgctga cgcgtctcaa ccaaaacagc aataccacta ttttgcttat
    53701 cagccatgac ttacaaatgc ttagccaatg ggcggataaa attaacgtgc tttactgcgg
    53761 tcaaacagtg gaaaccgcgc cgagtaagga gttggtgacg atgccacatc atccttatac
    53821 ccaggcgctg atccgcgcga taccagactt cggcagcgcg atgccgcata aaagtcgcct
    53881 caatacgctg cccggcgcta tcccactgct ggaacagtta ccgattggtt gtcgtctggg
    53941 gccacgttgc ccgtatgcac aacgagaatg cattgtgacg ccacgtttga cgggggcgaa
    54001 aaatcatctc tatgcctgtc atttcccgct gaacatggag aaagagtgag atgatcgaaa
    54061 cgctgcttga agtgcgtaat ttaagtaaaa cgttccgcta ccggaccggc tggtttcgtc
    54121 gtcagaccgt agaagcggta aaacccttga gctttacgct acgtgaaggc cagacactgg
    54181 cgattattgg cgagaatggt tcgggtaaat ccacgctggc aaaaatgctg gcgggaatga
    54241 tagagcctac cagcggcgag ttattgattg acgatcatcc actgcatttt ggcgattatt
    54301 ccttccgcag tcagcgtatt cgcatgattt ttcaggatcc ttcgacctcg ttgaatcccc
    54361 gtcaacgtat ctcgcaaatt ctggattttc cactgcgcct gaacaccgac ctggaaccgg
    54421 aacagcgtcg caaacagatt attgaaacga tgcgtatggt tgggctgcta ccggatcacg
    54481 tcagttacta tccgcatatg ttggcacccg gacaaaaaca gcgtctgggt ctggcgcgcg
    54541 cgctgatatt gcgcccaaaa gtcattattg ccgatgaagc cctcgcttca ctggatatgt
    54601 cgatgcgttc gcagttgatt aatctgatgc tggaattaca ggaaaaacag ggcatttcgt
    54661 atatttatgt tacccagcat atcggaatga tgaagcacat tagcgaccag gtgctggtga
    54721 tgcatcaggg cgaggttgtc gagcgaggca gcaccgcgga tgtgctggca tcgccgctgc
    54781 atgaactcac caaacggctg attgccggtc attttggcga ggcattgacg gcggatgcgt
    54841 ggcgtaaaga tcgctaattt tctgaatcct ccttccagat tattcacctc attctgacaa
    54901 aagattaaat cttgtcagaa tgaggtgata gataaaatta aatcaaatgc gcgtgattta
    54961 agacgcaatc tcactttgca ggaacgaaag ctctggcgat atcttcgcag ccgacgtttt
    55021 agtgatttca aatttcgccg tcaacatcca gtggggagct acattctcga ttttgcttgc
    55081 tgctcggcgc gtgtagtcgt tgagctggat ggtgggcagc atgatttagc agttgcctat
    55141 gattccaggc gcactagctg gcttgagtcg cagggctgga ccgtgctgcg tttctggaat
    55201 aacgagattg attgtaatga ggagacggtg ctggagaata ttctgcagga actgaaccgc
    55261 cggtcaccct ctccctgaaa gagcgagggg gcagaccgag ccgaatagct gttgtggtga
    55321 aaacatggag acggtgctgg agaatattcg gcaaggtctg aaccgtccca gccatcgcca
    55381 tgaaagggtt aggggctgta tgagcctgtt tgttgctggg gtaacaatat ttgcacaata
    55441 cggtcccctc gcccctctgg ggagagggtt agggtgaggg gaaaagcgcc ccccctgccg
    55501 cagcctgctc cggtcggacc tggcaactat agctactcac agccaggttg attataataa
    55561 ccgtttatct gttcgtactg tttactaaaa cgacgaatcg cctgattttc aggcacaaca
    55621 agcatcaaca ataaggatta aagctatggg ttttctttcc ggtaagcgca ttctggtaac
    55681 cggtgttgcc agcaaactat ccatcgccta cggtatcgct caggcgatgc accgcgaagg
    55741 agctgaactg gcattcacct accagaacga caaactgaaa ggccgcgtag aagaatttgc
    55801 cgctcaattg ggttctgaca tcgttctgca gtgcgatgtt gcagaagatg ccagcatcga
    55861 caccatgttc gctgaactgg ggaaagtttg gccgaaattt gacggtttcg tacactctat
    55921 tggttttgca cctggcgatc agctggatgg tgactatgtt aacgccgtta cccgtgaagg
    55981 cttcaaaatt gcccacgaca tcagctccta cagcttcgtt gcaatggcaa aagcttgccg
    56041 ctccatgctg aatccgggtt ctgccctgct gaccctttcc taccttggcg ctgagcgcgc
    56101 tatcccgaac tacaacgtta tgggtctggc aaaagcgtct ctggaagcga acgtgcgcta
    56161 tatggcgaac gcgatgggtc cggaaggtgt gcgtgttaac gccatctctg ctggtccgat
    56221 ccgtactctg gcggcctccg gtatcaaaga cttccgcaaa atgctggctc attgcgaagc
    56281 cgttaccccg attcgccgta ccgttactat tgaagatgtg ggtaactctg cggcattcct
    56341 gtgctccgat ctctctgccg gtatctccgg tgaagtggtc cacgttgacg gcggtttcag
    56401 cattgctgca atgaacgaac tcgaactgaa ataatcgttc tgttggtaaa gatgggcggc
    56461 gttctgccgc ccgttatctc tgttatacct ttctgatatt tgttatcgcc gatccgtctt
    56521 tctccccttc ccgccttgcg tcaggataac gatttccttt acgaccaagg agcgcccatg
    56581 gaacaacgcc acatcaccgg caaaagccac tggtatcatg aaacgcaatc cagtactacg
    56641 gagtatgacg ttctgcctct ggtcccggaa gccgcaaagg tcagcgatcc ctttctactc
    56701 gacgtgatcc ttgaaaaaga aacgctggcc cccttccttt catggctgga ccctgcgcgt
    56761 gttcttgcag tggatttgtt ccctgaccag cttaccgtga cccgttcaca gaccttcacc
    56821 gcttatgaac gcttgtcgac ggccctgacg gttgctcagg tttgcggcgt ccagcggtta
    56881 tgtaactact attcggcgcg acttacgccg ctccccgggc ctgattccac cagggaaagt
    56941 aatcatcggt tggcacaaat cacgcaatat gcccgccaac tggctagctc gccttctatt
    57001 atcgacaacc gatcgcgcca gcatctgaat gacgtcggtc ttactgcctg ggactgtgtg
    57061 atcattagcc aaatcattgg ttttattggc tttcaggcgc ggacaattgc gacatttcag
    57121 gcttatctcg ggcatccggt acgctggtta cccgggctgg agatacaaaa ctacgccgac
    57181 gcgtcactgt ttgctgatga atcattacgc tggcgaagca gctatgaggt ggaaaaacta
    57241 cctgaagagc acacaaaaag ttcaactgca gaactttgcc aactggccga aatactctct
    57301 ctccacccta tttcactttc ccttctcgaa aagttgttaa acagcacacg gggcaataca
    57361 cagccggata atcagcttgc ggcgttgtta tgcgcgcgta taaatggcag tcctgcttgt
    57421 tttgccacct gtatggattc atcaaatgaa tataaaaaaa tcagcaccct tatgcgcaag
    57481 ggcgaaaatg aaattaacca atgggctgac cgtcattctg ttgagcgcgc taccgttcag
    57541 gcgatacaat ggctgacccg agcacccgat cgctttagcg ccgcccagtt cagcccttta
    57601 ctcgaacacg aaaaatcatc aacgcagatt attaatctgc tggtatggag cgggctgtgt
    57661 ggctggataa atcgcttaaa aatcgcgttg ggtgagacat attaaccttg ccgcgtcaga
    57721 cagattcgcg taaaactgtc agccgctcta atggccacca aaatagacaa ttatgtttca
    57781 ggacaacccg ctgctagcgc agcttaaaca gcaactgcat tcccagacgc cacgcgctga
    57841 aggggtggta aaagccacag aaaaaggctt tggcttcctg gaagtcgacg cgcaaaaaag
    57901 ttatttcatt ccgccgccgc agatgaaaaa agtcatgcat ggcgaccgaa ttatcgcggt
    57961 gatccacagt gaaaaagaac gtgaatccgc agagccagaa gaactggttg aaccgttcct
    58021 gactcgtttc gtgggtaagg ttcagggcaa aaatgaccgt ctggccatcg ttcctgatca
    58081 tccactctta aaagacgcca ttccttgccg cgcagcccgt ggcctgaacc acgagtttaa
    58141 agaaggcgac tgggcggttg ccgaaatgcg ccgtcatccg ctgaaaggcg atcgttcttt
    58201 ctatgcagaa ctgacacaat acatcacttt tggtgacgat cactttgtac cgtggtgggt
    58261 tacccttgca cgccataatc tggaaaaaga agcaccagac ggcgtcgcta ccgaaatgct
    58321 cgatgaaggt ctggttcgtg aagatctgac cgcgctggat tttgtcacca tcgacagtgc
    58381 cagcacagaa gatatggatg acgccctttt cgctaaggcg ttgccggatg acaaacttca
    58441 gctgattgtg gcgattgccg atccaaccgc gtggattgct gaaggcagca agctggacaa
    58501 agccgcgaaa attcgcgcat tcaccaacta tctgcctggc ttcaacatcc ctatgctgcc
    58561 tcgcgagctt tctgacgatc tctgctcact gcgcgccaat gaagtccgcc cggtactggc
    58621 atgccgcatg acgctctccg ctgatggcac cattgaagat aatatcgaat tctttgccgc
    58681 caccatcgaa tccaaagcaa agctggtgta tgaccaggtt tctgactggc tggaaaatac
    58741 cggtgactgg cagcctgaaa gtgaagcaat tgccgaacaa gtccgtttgc tagcgcaaat
    58801 ttgccaacgc cgcggcgagt ggcgtcataa ccacgcactg gtgtttaaag atcgcccgga
    58861 ttaccgcttt attctcggtg aaaaaggtga agtgctggat atcgtcgccg agcctcgtcg
    58921 cattgccaac cgtatcgtcg aagaagcgat gattgccgct aacatttgtg cggcccgcgt
    58981 actgcgcgat aagctcggtt ttggcatcta taacgtgcat atgggctttg atccggcgaa
    59041 tgccgacgcg ctggcagcgt tgctgaaaac gcacggtctg catgtcgatg ccgaagaagt
    59101 gctcacgctg gacggtttct gcaaactgcg tcgtgaactg gacgcgcaac caactggttt
    59161 cctcgacagc cgcattcgtc gcttccagtc atttgctgaa attagcactg aacccggtcc
    59221 tcactttggc ctcggtctgg aagcatacgc cacctggact tcgccgatcc gtaaatatgg
    59281 cgacatgatc aaccaccgtc tgctgaaagc ggttatcaaa ggcgaaactg cgacgcgccc
    59341 acaggatgaa atcactgtcc aaatggccga gcgtcgccgt ctcaaccgga tggcagaacg
    59401 tgatgttggt gactggttat acgcacgctt cctgaaagac aaagccggga ccgacacccg
    59461 tttcgcagcg gaaattgtcg atatcagccg tggcggcatg cgtgttcgtt tggttgataa
    59521 cggcgctatc gcctttattc cggcaccttt cttacacgct gtgcgcgatg aactggtttg
    59581 cagccaggaa aacggcactg tacaaattaa aggtgaaacg gtttacaaag tgactgacgt
    59641 tattgacgtc actattgccg aagtccgcat ggaaacccgc agcattattg cgcgcccggt
    59701 cgcgtaatct cctttcacgg cccattcctc atggatgggc cgtttatttc cccgctctac
    59761 cttcgttata tccaggcaga ttttttaact gactttcgtt tgaaaactgg cgtttttcca
    59821 aaactggatt acaaataaat atataaaaaa aacaatgcgt ttagccgccg ttaatttcat
    59881 gtaagtcatg ttgttccttt tatttaaccg cggactccgc tgttaaccgg aggatatgca
    59941 tcatgaaaac cgttagggag tccacaacgt tgtacaactt tctcggatcg cacaatccat
    60001 actggcggtt gacggaaagc agcgatgttt tgcgcttttc taccaccgaa accacagaac
    60061 ctgatcgtac attgcagtta tctgccgaac aggctgctcg catcagggaa atgacggtca
    60121 tcacctccag cctgatgatg agtctgaccg tcgatgaaag cgatctttct gtgcatctgg
    60181 taggacgaaa aatcaataaa cgggaatggg ctggcaacgc gtctgcatgg catgacacac
    60241 cggcggttgc tcgtgattta tcacacgggc tttcctttgc tgagcaggta gtttctgaag
    60301 cacattccgc aatagtgatt ctcgacagcc gggggaatat ccaacgcttc aatcggttat
    60361 gtgaagatta cacagggttg aaagaacacg acgtcattgg gcaaagcgtg tttaaactgt
    60421 ttatgagccg tcgtgaagct gcggcatcca ggcgcaataa ccgtgtattt tttcgaagcg
    60481 gcaatgcata tgaagtcgaa ctgtggatac caacatgtaa aggccagcgg ctgtttctgt
    60541 ttcgcaataa atttgtccac agcggcagtg gcaaaaacga gattttttta atctgttccg
    60601 gcaccgacat taccgaagag cgccgcgctc aggagcgact gcgtattctg gcaaataccg
    60661 acagtatcac cggactgccg aatcgtaacg caatgcagga tttaatcgat cacgctatta
    60721 atcatgcaga taacaataaa gttggggttg tgtatcttga tttggataat ttcaaaaagg
    60781 tcaacgacgc ctatgggcat ttgtttggtg accagttatt acgcgacgtg tcattggcta
    60841 ttttaagctg tctcgaacat gaccaggtgt tggcgcgtcc aggtggggat gagtttctgg
    60901 tactggcatc caacacctca caaagcgcgc tggaagcaat ggcatcacga attttgaccc
    60961 gcttacggct cccctttcgc attggtttaa ttgaagttta taccagctgt tcagtaggta
    61021 ttgcactctc tcccgaacat ggttcagaca gcacggctat tattcgtcac gccgacacag
    61081 caatgtacac agcgaaggaa ggcggacgag gacaattttg cgtttttacc ccagaaatga
    61141 atcaacgggt atttgaatat ctctggctgg ataccaactt gcgtaaagca ctggaaaacg
    61201 atcagttggt tattcactat caaccgaaaa tcacctggcg tggcgaagtg cgcagtctgg
    61261 aagcactagt acgttggcag tcacctgaac gtgggttgat tccaccgttg gacttcattt
    61321 cctacgccga agagtcaggg ctaattgtgc ctttaggccg ttgggtgatt ctcgatgtcg
    61381 tacgccaggt ggcaaagtgg cgggataaag gcataaacct gcgagtggcg gtaaatattt
    61441 ctgcacgtca gctcgccgat caaaccattt tcaccgccct gaaacaggtt ctccaggaac
    61501 tcaattttga atactgccct atagatgttg aactgacaga gagttgtctg attgagaatg
    61561 atgaactggc actgtctgtt attcaacaat ttagccaact aggtgcgcaa gtgcatctgg
    61621 atgattttgg taccggctac tcttcacttt cgcaactggc gcgctttccg atcgatgcca
    61681 tcaaacttga ccaggttttt gttcgagata ttcacaaaca acctgtctcg cagtcactgg
    61741 tccgggcgat cgtcgctgtg gcccaggcat tgaatcttca ggtgatcgcc gaaggtgtag
    61801 agagtgcaaa ggaagatgct tttttaacca agaacgggat caatgagcgg caaggatttt
    61861 tgtttgccaa accgatgccc gccgtcgcct tcgaacgctg gtataaacgc tatctgaagc
    61921 gcgcataagt agatgaatat atatacttag cgctatatcc cgtcattata tatcgtattc
    61981 ctggatgata attagccgtt gctgttaaac acttctcttt tagcggcaat ttttgcatta
    62041 ttcattttcc cccttttgct ataaggatgt ccttgatgtc tgaatttgat gcccagcgcg
    62101 ttgccgaacg tattgatatt gtgttagata tccttgtggc aggcgattac cactctgcga
    62161 tccataatct cgagatactt aaagcagaac tcttgcgcca ggttgctgaa tctacgccag
    62221 acatcccgaa ggcaccgtgg gagatttaac aatcgtgcct acaggttttc ctatttgagg
    62281 atgcccggcg cgtcagtatt tttttattaa gtattataac gttataagaa ttacagcgat
    62341 gaattcccga caacaaacta ttctacagat ggtcattgac cagggtcagg ttagcgtaac
    62401 cgatctggca aaagccactg gagtttctga agttaccatt cgccaggatc tcaacacact
    62461 cgaaaaactg agttacctcc gccgtgcaca tggctttgct gtttcgcttg atagtgatga
    62521 cgtcgaaacc cgtatgatga gcaactatac gctgaagcgt gaactcgccg agtttgccgc
    62581 gtcgctggtt caaccgggcg aaaccatctt tatcgaaaat ggcagcagca atgccctact
    62641 cgcccggact ctgggcgagc agaagaaaaa tgtcactatc atcacggtca gcagctacat
    62701 cgcgcatttg ctgaaagacg cgccttgtga agttattttg ctcggtggcg tgtatcagaa
    62761 aaaaagcgaa agtatggttg gccctttgac acgccagtgc atccaacagg tgcatttcag
    62821 caaagcattt attggtattg atggctggca acctgaaact ggatttaccg gtcgcgatat
    62881 gatgcgtacc gatgtggtca atgccgtgct ggaaaaagag tgcgaagcga tagtcctgac
    62941 tgacagctcg aaatttggtg ctgtacattc atactccatc ggtcccgttg agcgattcaa
    63001 tcgcgtgatt accgattcga aaatacgcgc cagcgatctg atgcatcttg agcacagtaa
    63061 actcaccgtt cacgtcgttg acatttaacc atttcccttc tctacggatg atttgcagtt
    63121 tggcaaatca tccgctctaa gatgattcct ggttgataat taagactatt tacctgttat
    63181 taacactctc aagatataaa attattatca gcgatataac aggaagtcat tatcacctgc
    63241 gtgatataac cctgcgcgcg agcagatttc acggaataat ttcaccaggc ttattcttag
    63301 ctattatagt tatagagagc ttacttccgt gaatcataaa ttcaggagag agtattatgt
    63361 ttgtaacgag caaaaaaatg accgcggctg ttctggcaat tactttggca atgtctctga
    63421 gtgcctgttc taactggtct aaacgggacc gcaacaccgc aatcggcgcg ggtgcagggg
    63481 cattaggcgg tgcagtactg accgatggca gtacgttggg tacattaggt ggtgcagctg
    63541 tcggtggtgt tattggtcac caggtcggta aataatcgta aataaatgtc gattatcgac
    63601 tcgcaattat aatacgcttg attctgttca gtacgaaata actgaataat acgcacagta
    63661 aaatattcga aagccacgga tatatccgtg gctttttatg ttaaccgcct gcgagtttta
    63721 ccttcatccc tttcgcttca agtagtgatt ttaataaatc acgcttatcg ccctggattt
    63781 caataactcc atctttaact gctccgccgc agccgcattt tttcttcagt tccgctgcaa
    63841 gttttgtcag ttcggcatca tcgagatcga caccggtaat caggcaaacg cccttacctt
    63901 tacgtccact ggtctgacgc tgaatacgca ccacaccgtc gcctttaggg cgtacagggg
    63961 ccgctttggg ctcatcaata cgtccggttt ccgttgagta gaccagacgg ctgttggaat
    64021 cactcatcat gcactccgct gtaaagaggc gttgatcgct ttcagcgtct gcgctggatc
    64081 taccgattgc gttaccgggc gaccaatcac catataatca acaccagccg acaacgcctg
    64141 ttctggcgtc ataatgcggc gctggtcacc agcttcactc ccctgcggac gaatgcccgg
    64201 cgtaaccagt ttgaactcct gaccgaatac ctgtttaaag cgcacagctt cctgagcaga
    64261 acacaccaca ccatcaaggc cacatttttg cgtcagtgcc gccagacgtt ctgcataatc
    64321 tgcaggtgac agtgtcatgc caagatcgac caggtcgctg gcttccatgc tggtcaacac
    64381 tgtcacagca atcaaaagcg gtgcatcttt gccaaacgga accagtgcct cacgcgctgc
    64441 ggtcatcata cgcgccccac cagaggcatg aacattcacc atccacacgc ctaagtcagc
    64501 tgcagcagcg acagcgtgcg ctgcagtgtt ggggatatcg tggaatttca ggtcaagaaa
    64561 gatatcaaaa ccacgctgtt gaagttcgcg cacaaactgt ggcccaaaca atgtaaacat
    64621 ctctttgccg accttcagac gacaatcgcg tgggtcgatc ttgtcgacaa aggccagcgc
    64681 gtcatcacga ttatgataat caagggcaac aaccacagga gaattcgtaa cagcgcggga
    64741 agaagatgaa gcagttaacg tcatgaccag accttcttga tgatgggcac cggaagtggc
    64801 gcgaaacagg taaacggcga gcattctacc cgtggaaata aaaaattaac agttgcgatt
    64861 tctcccctgg caggcttttt ctgcgccgtc gttgccggag cacaatggaa cattaataat
    64921 tagtatgttg taactaaagt cggatttttt ttaaaaatta caggccatca agaccgcgaa
    64981 tcggtttaat ggttgaccag gcccgacaag acggacaatg ccagtagagg gtgtatgcgg
    65041 taaaaccaca tttctggcaa cgataacgag gcttactacg taccttctcg ccaaccatgt
    65101 cacgcagcac catcaggctc tctttggcac gcccttcttc cgcttcattt aagtggtaat
    65161 ccattaactt atggaacaca cgcatggtcg gatgacgctg aagctggcgc gtaatataga
    65221 cctgtgcggc ctcactaccg tcgcgcgctt cgatgatatc agcaagcatc aattcagcat
    65281 cggcaccggt gttctcttcc accgcacgct gcaggaattc tgcccattcg gcagttttac
    65341 ccaactgctg atagcaggtt tgcaacattt ccagcgtttc gctgaccagt tctctgtcct
    65401 gggatatcac gcgttgcaga ctttcgacgg ctttggcgta ttctcctttc gccataaaca
    65461 cgcgtcccat cattatggat acgcgggcgc tgtttttatc tgccgccgcc ccttttttta
    65521 gcaaggtcat ggcacgatcg agatcgtcgc tggccatatg ctgcagggct aactcacagt
    65581 agaaatgggc aatttcgacg cgctgtttat ctttacccag cttcaccagg cgttcggcaa
    65641 catcaattgc tttctgccac tcactggtag cctggtagat ttgtagcaac tgttgcagcg
    65701 cgccaatgcg gaagtcagtt tcatcggtca gctgattgaa catgtcttcc gcgcggtcat
    65761 ataacccggc ggccatgtaa tcacgcccca gttgttgaat cgccaacaga cgctgttcat
    65821 aggtcagcga ggcgctttcc attagggtct gatggatgcg aatagcgcga tcaacttcgc
    65881 cacgcgaacg gaacaggttt ccgagcgtaa ggtgggcttc aacggtgcct gtatcctctt
    65941 taagcatatc gagaaacagg tctaccgctt tatcctgttg attactaagc aggaagttaa
    66001 cccccgctac gtaatcacgc gacaagcggt tggcttcatc ttgcttgttt tgttgcgcac
    66061 ttctgcggcc catataccag ccataggcag cggctacagg caaaagcaga aacaacaact
    66121 ccagcataga aagttattcc ttcgccgctg acgagtgcgg cactacagcc acgtcagtcg
    66181 cgggtgaaag ctggttttcc agtcgcttta ttttacgttc agcgcgcgcc agggaaacac
    66241 gaactcgcag ccagaacagg ccacaaatca accaaccgat agcaaacccc gcagcaaaca
    66301 ataccgccag caatgtggaa atacggtact ccccttgcgc taacagataa ttaaacgtca
    66361 cctgttgatc gttctgcgca cccaacgtga ccgaaatcac gaagatcgct aacaccagta
    66421 agaaaatgag taaatatttc acattacttc ccgttatgtg gttagagcga ataaattatg
    66481 gtcaacttac cgcaatagcc ctttaaagta ccattttcgc gccgtctgcg aaatggcatc
    66541 cacacgcatt gttgatgatt taagggctaa attcggaaaa tcaaccagcg ttaactttct
    66601 tgttctcgtt gcgctatttc gcgattttct tccgcaggtg gtgttaatgg cccacaaatt
    66661 cgttgcgcaa gccacgttgc caccgccacc agcgcccacg aaatcaacgt agctactacc
    66721 agatcgcgtg gccaatgcat cccgagcagc aggcggcttc ccatgactcc cgttgcccag
    66781 accagcaaga tagcaatggt taacgttcgc cgacgcggcc acagcaaacc aacggccagc
    66841 agtgcccaac tggcagcaaa catcgtgtga ccggaaggaa aggcaaaccc cgtctctttc
    66901 tgccagtgtg aacgcaaata ttgtgggata tttttctctt cagccaactg ttctttcact
    66961 agatttccgc gttctgctcg ctttaaagtg tagaactcat caaccggaat atgatgtgtt
    67021 ttttccagcc agataacaaa aggtcgtggt tcctggactt tgtctttgat ccaggattta
    67081 acgccttgtc ccacaaggat tgcggccgcc agaatggcaa ataatacaaa ggcagcctta
    67141 atgcgaaaac gcagacacca gagaaaccag ccgaataaaa tcaaatgtgt aatgacgccc
    67201 cagggctggg tgacagtttc agtaacccaa aaagccgctt ttagtagcca actttgttct
    67261 ccaggttgcc aacgccagcc agaaatccat acggctactg gcatgacaag caatagtgca
    67321 gctcccactg cggtacgtct ggcaatcgaa cgcatggcct ctcctttttg ataagtccca
    67381 caatcataac tgaaaacgcc agttccagga aaaattgaca gatttgtgcc attccgtgaa
    67441 cgatcgacgc gtcgtgatta ggtgaacccc ttctcgttat ggcaaaataa gccaatacag
    67501 aaccagcatt atctggagaa tttcatgcag cttaaacgtg tggcagaagc caaactgcca
    67561 accccatggg gcgatttcct gatggtggga tttgaagaac tggcaaccgg acacgatcat
    67621 gtcgcgctag tctatggcga tatttccggg cataccccgg tacttgcgcg cgtccattcc
    67681 gaatgtctga ccggtgacgc cctgttcagc ttgcgctgcg attgtggctt ccagctcgaa
    67741 gcggcattga cgcaaattgc cgaggaaggc cgtggtattt tgctgtatca ccgtcaggaa
    67801 ggtcgtaaca ttggtctgct gaataaaatc cgcgcttacg cactgcagga tcaaggttac
    67861 gataccgtag aggctaacca ccagttaggc ttcgccgctg atgagcgcga cttcactctt
    67921 tgcgctgata tgttcaaact ccttggcgtc aatgaagtcc gcttgttaac caataacccg
    67981 aaaaaagtcg aaattctgac cgaagcaggg attaatattg ttgaacgcgt accattgatt
    68041 gtaggtcgta accccaataa cgaacattat ctcgatacca aagccgagaa aatgggccat
    68101 ttgctgaaca aataaccctc ttgcattgtg taattcattt gcttgccgga agcaaaataa
    68161 ccggcaagca aatagttgtt acttcaacat attacgaatg acataatgca aaatgccgtc
    68221 gttctggtag taggtcaact ccgtcgcggt gtcgatacga caacggcagg gtacgacttc
    68281 ctggctacca tccgcgcgcg taagcgtcac cggaaccgtc gcgccgggtt gtaggttttg
    68341 cagatcgcca atatcaatct tctcttcccc ggttagccct aacgttttac gcgttacgcc
    68401 ttgcggaaat tccagcggca ggatgcccat gccaattaaa ttcgaacggt gaattcgttc
    68461 aaacgattcg gcaatcacca cacgaatacc aagcagacgc ggaccttttg ccgcccagtc
    68521 acgactggag cctgatccat actctttccc ggcaatcacc gccagcggcg tttgctcctg
    68581 cttatagcgc atcgcagcat cataaataga gactacgtcg ctgtcaggta aatgccgcgt
    68641 catcccccct tcaacgccag gcaccatttc attacggatg cgaatattgg cgaaggtgcc
    68701 gcgcatcatc acttcatggt taccacgccg cgaaccgtag gagttaaagt cttttcgctc
    68761 aacaccccga ccttgtagat atcgacccgc tgggctgtcg ggcttaatac tgcccgccgg
    68821 agagatatgg tcagtggtga ctgaatcccc cagcattgcg aggatccgcg caccgtgaat
    68881 atcttccact ggtgctggtg ttgcctgcat ttcatcaaag aaaggcgata agcgaatata
    68941 ggttgagtcc tcctgccaac cgtaggtatc ggatcgtgtg acgttaattc ccttccactc
    69001 tgctgtgcct tcaaaaactt ctgcgtactc tttgcggaac atttctgtgg agacttgttc
    69061 taccgcacgg gcaatttctt gtgccgatgg ccagatatct ttcagataaa ccggatcgcc
    69121 tttgcgatca tggccgatag gctcagaagc caggttgata ttcatatttc ccgccagcgc
    69181 ataggcaacc accagcggcg gcgaggccag ccagttagtt ttaaccagcg gatggatacg
    69241 gccttcaaag ttacggttgc cggacagcac cgcaccgacg gttaaatcgc cttttttgat
    69301 tgccgtttcg ataggatcgg gcagcggccc agagttacca atacaggtgg tacaaccgta
    69361 tcccacaagg ttaaacccca gttcgtcgag atacggtgtc agtttcgctt ttgccagata
    69421 atcagaaacg actttcgaac ccggtgccag cgacgctttg acccatggtt gccgcttgag
    69481 gcccagagtt acggcttttt tcgccagcaa gcctgcggcc atcagcacac ttgggttaga
    69541 ggtgttggtg cacgaggtta tcgcagcaat gaccacagcg ccatcaggta actgatactg
    69601 atgtccgttc ataacataat cgaccggctg gcgatcttta tgcgtggcat tcacttccag
    69661 ttcgttactg gcggcaaatg cttttggtac atcgggcagt gcaacgcgat cctgtgggcg
    69721 tttaggccct gccaggctcg cttcaacgtc attcatatcc agttctaacg tactggtaaa
    69781 aattggttca tcgcccgggt tacgccacat gccctgcgct ttggcatatt tttcgaccaa
    69841 ctcgacctga tcttcgctgc gcccgcttaa acgcatgtaa tcgagggtta cagcatcgat
    69901 tgggaagaag ccacaggtgg caccatattc tggcgacata ttggcaatgg tggcgcgatc
    69961 cgccaacggt agtgaatcca gaccatcacc ataaaattcg acgaatttcc ccaccacgcc
    70021 atgtttgcgc agcatttggg taacagtgag aaccaggtct gtggcggtaa taccttcacg
    70081 taattttccg gtaagtttga agcccactac atccgggata agcatggaaa ccggctggcc
    70141 taacattgcg gcttctgctt cgatcccacc aacgccccac cccagcacgc caaggccgtt
    70201 gatcatggtg gtgtgcgagt cagtaccaac gagtgtatcc ggataagcaa tccattcacc
    70261 gtcctgcaat tcactccaca ctgctttgcc gagatattcg aggttaacct gatggcaaat
    70321 gcctgtgcct ggcggcacga cgctaaaccg actgaacgct tgctttcccc atttcaggaa
    70381 cacataacgt tcgtggttgc gctccatttc caggcgtacg ttttcttcaa atgcctcatc
    70441 atcaccaaaa cgatcgacgg tcaccgagtg gtcaatgacc aggtcgaccg gtgagagcgg
    70501 gttaaccttt gcagtatcgc cgccgaggcg tttaaccgct tcgcgcattg ccgccagatc
    70561 aacaacggca ggtacgccgg taaagtcctg catcagcacc cttgccgggc ggtaggcaat
    70621 ttcacggtca gcatgggcat ttttcagcca tcctgccagc gcgtggatat cctcttcggt
    70681 aaccgagtta ccatcctgcc agcgcagcag gttttcgagc aaaactttga gtgacttggg
    70741 tagacgggtg atatcgccca gtgatttagc agcaagcggc aggctgtagt agtggtaagt
    70801 tttatctttg gcctgcaacg tgtccttact ggcttctcgt agggttgacg acatagctcc
    70861 tccttaatga cagggttgcg aagccctgat tctcttcagg gtgaatatta aagataacac
    70921 aaacatcgcg taacgatttg ataacaaccc aaattgataa aagaggagaa accttgtggc
    70981 aaagcaaatg acaaccccgc cgcagcgggg tcaaggatca gtgagtaatg atccagagga
    71041 gttcggccca gaagagcatc gacagagaaa acgcgtccat ccaggaccaa tatttcatat
    71101 ttgtgttgat cataggctac acccttaacg gttattattt tgtgttgaga taactcaagc
    71161 tgttattgct gcggtgtatt aaaagccctt taattcatta aaaatgggta ataagaatga
    71221 tgataattat tgtttcggct gatcatcttc agcaaacagt tctataaagg cttgctgctg
    71281 cgatgttagt tgccagtcgt ctggaataac gacggaacat tcccgtttcg tttctgtttc
    71341 attgtcacta tgctggcata atggtgacga ctccagttgc tcctgaccga ccatagttat
    71401 ccccacactt tccaaatcag cagtgcgaca accacccaga aaagtgcaga accaagaaaa
    71461 accgccagcc aggctttacg ttttaattca ggatcgcggc ggggttcctg atttccagaa
    71521 ggcattgcta acctcatata atcgccatca cttatcagca agacgttgaa cgattggtgt
    71581 aattaatcat acgatgagac aaatcctaaa gaaactttag tcaaaaatcc agcgaattta
    71641 cgaatcgtct ccagtgaata attcaatctt ttgacctgaa atagatattt gaaaactgga
    71701 gtttgcgagg cgggtaatta gacactactt tacaggtaat ttaccctata aatatgaggg
    71761 ataaaaatat tgtgcacggt atagaaataa gtaacaaaag agaatatatt ccggcacctt
    71821 cgctacataa aaggtgccga aaataacgca agaaattatt tttccggcag ttttatatct
    71881 ttaaacatga cctcaatttc ttcattagag cgcaatgcga cagccgcatc aacgacatca
    71941 cgcgttaaat gcggtgcaaa acgctgaatg aaatcataca tataactgcg caagaaagta
    72001 ctacggcgaa aaccaatttt ggttgtactg tggctgaaga tatcgtgagc atcaacacgc
    72061 acaaggtcgg gatcggcgac cggatccacc gccatgctgg caatgacccc tacccccagc
    72121 cctaaccgga cgtaagtttt aatgacgtca gcatccgttg ccgtgaaaac gatacgcggc
    72181 gttaaccctg cgcgattaaa ggcagtatcc agttctgaac gtccggtaaa gccgaaggta
    72241 tatgtcacca acggatattg cgccagttct tcaatggtaa tggctttttt gcctgccagc
    72301 gggtgatccg gagtgactac aatagcccga ttccagtggt agcacggtaa catcactaaa
    72361 tcttcataca gatgcagcgc ttctgtggcg atagcgaaat cagcattgcc tttagagacg
    72421 gcatcagcaa tttgtgtcgg cgagccctgg tgcatatgca aagaaacgcg aggataacgc
    72481 tcaataaagc ctttgatgac gtttggtaat gcgtagcgtg cctgggtatg cgtggtggcg
    72541 atatacagtg aacctttatc cggccaggtg tgctctccgg caaccgattt tatggcatcg
    72601 actttcgaca ggacttcgcg agcgatacga attatttctt gccctgctgg cgttacctgc
    72661 gtcaggtgct tgccgcttcg ggaaaaaatt tgaatgccta gctcgtcttc cagcattctg
    72721 acttgtttac tgatcccggg ttgtgatgtg taaagtcctt ccgctgttga tgagacattc
    72781 aggttatgat tgaccacctc aacaatatag cgaagttgtt gtaatttcat gttaaaccat
    72841 ccacttagac gccatcagaa catcgttttt tcgtcacacc tggcgggtga ctaatacgat
    72901 ttaataataa aaaaggtgct aactataac
//
LOCUS       DAPHKZ010000008        71035 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.008, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000008 DAPHKZ010000000
VERSION     DAPHKZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 71035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71035
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.008"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..766)
                     /locus_tag="RH288_000530"
     CDS             complement(<1..766)
                     /locus_tag="RH288_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDV4029627.1"
                     /translation="MSKISGWNFSQNITSADNCKQKNEDLDTWYVGMNDFARIAGGQN
                     SRSNILSPRAFLEFLAKIFTLGYVDFSKRSNEAGRNMMAHIKSSSYIKNNDGSEIMKF
                     VMNNPEGERADLSKVEIEITLASAFNNGIREGHTVIIFPQPDGSTNRYEGKSFERKDE
                     SSLHLITNKILACYQREANKEIARLLNIPQELNNSQDLNNSQVSCKDSVDSTITDLLE
                     KPLNNALLAIRKEHLLLMPYVCNESISYLLGEKGILK"
     gene            complement(889..1341)
                     /gene="tabA"
                     /locus_tag="RH288_000531"
     CDS             complement(889..1341)
                     /gene="tabA"
                     /locus_tag="RH288_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin biofilm protein TabA"
                     /protein_id="HDV4029628.1"
                     /translation="MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRL
                     FYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAF
                     LPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA"
     gene            complement(1486..2079)
                     /locus_tag="RH288_000532"
     CDS             complement(1486..2079)
                     /locus_tag="RH288_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709951.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDV4029629.1"
                     /translation="MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTD
                     YLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLVEVLKEAAR
                     RYSQNGGCAGCMVLEGIHSHDPLARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFM
                     STVMSGLSAKAREGHSIEQLCATAALAGEAIKTLLKE"
     gene            2150..2863
                     /gene="bdcA"
                     /locus_tag="RH288_000533"
     CDS             2150..2863
                     /gene="bdcA"
                     /locus_tag="RH288_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV4029630.1"
                     /translation="MGAFTGKTVLILGGSRGIGAAMVRRFVTDGANVRFTYAGSKDAA
                     EHLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRL
                     FKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
                     ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHGFMAIKRHGQPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            2994..3389
                     /locus_tag="RH288_000534"
     CDS             2994..3389
                     /locus_tag="RH288_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDV4029631.1"
                     /translation="MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGT
                     PEPDFQQQVRLAFDNLHATLAVAGCTFDDIIDVTSFHTDPENQFEDIMTVKNEIFSAP
                     PYPNWTAVGVTWLAGFDFEIKVIARIPEQ"
     gene            3670..3804
                     /gene="pyrL"
                     /locus_tag="RH288_000535"
     CDS             3670..3804
                     /gene="pyrL"
                     /locus_tag="RH288_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HDV4029632.1"
                     /translation="MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCPGVRR
                     "
     gene            3808..4743
                     /gene="pyrB"
                     /locus_tag="RH288_000536"
     CDS             3808..4743
                     /gene="pyrB"
                     /locus_tag="RH288_000536"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDV4029633.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
                     VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEE
                     VMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIAT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL"
     gene            4756..5217
                     /gene="pyrI"
                     /locus_tag="RH288_000537"
     CDS             4756..5217
                     /gene="pyrI"
                     /locus_tag="RH288_000537"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HDV4029634.1"
                     /translation="MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPER
                     IDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN"
     gene            5290..5676
                     /gene="ridA"
                     /locus_tag="RH288_000538"
     CDS             5290..5676
                     /gene="ridA"
                     /locus_tag="RH288_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HDV4029635.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPA
                     DVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            complement(5882..8578)
                     /gene="mgtA"
                     /locus_tag="RH288_000539"
     CDS             complement(5882..8578)
                     /gene="mgtA"
                     /locus_tag="RH288_000539"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDV4029636.1"
                     /translation="MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTAVPPSLSAHCLK
                     MAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFN
                     ILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
                     RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLP
                     VEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQES
                     EPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLP
                     MIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDIS
                     GKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERR
                     RMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQ
                     GLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVK
                     ILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER
                     IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLE
                     EGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVS
                     QVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPET
                     QTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPL
                     ASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(8719..8772)
                     /gene="mgtL"
                     /locus_tag="RH288_000540"
     CDS             complement(8719..8772)
                     /gene="mgtL"
                     /locus_tag="RH288_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003933616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HDV4029637.1"
                     /translation="MEPDPTPLPRRRLKLFR"
     gene            8957..9904
                     /gene="treR"
                     /locus_tag="RH288_000541"
     CDS             8957..9904
                     /gene="treR"
                     /locus_tag="RH288_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator TreR"
                     /protein_id="HDV4029638.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
                     GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAM
                     KQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPE
                     IVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS"
     gene            10023..11444
                     /gene="treB"
                     /locus_tag="RH288_000542"
     CDS             10023..11444
                     /gene="treB"
                     /locus_tag="RH288_000542"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HDV4029639.1"
                     /translation="MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANAR
                     PKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARQNMK
                     WHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
                     WLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDF
                     GMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHA
                     LIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQ
                     SMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGIN
                     LKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAI
                     IIPIVLTSFIYQRKYRLGTLDIV"
     gene            11494..13149
                     /gene="treC"
                     /locus_tag="RH288_000543"
     CDS             11494..13149
                     /gene="treC"
                     /locus_tag="RH288_000543"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDV4029640.1"
                     /translation="MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHK
                     LGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMV
                     FNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
                     LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGD
                     GRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFN
                     FHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFG
                     DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELR
                     NDGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALT
                     DESSVFYTYQKLIALRKQEAVLTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSRG
                     IQPWQPGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK"
     gene            13543..15681
                     /gene="nrdD"
                     /locus_tag="RH288_000544"
     CDS             13543..15681
                     /gene="nrdD"
                     /locus_tag="RH288_000544"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDV4029641.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAA
                     VVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEI
                     RGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTASYNKHRKTAEEWNIPDAEGYANSRTIKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHETINALFGGEHVY
                     DNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            15840..16304
                     /gene="nrdG"
                     /locus_tag="RH288_000545"
     CDS             15840..16304
                     /gene="nrdG"
                     /locus_tag="RH288_000545"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HDV4029642.1"
                     /translation="MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSG
                     QTFTKAMEDQIINDLNDTRIKRQGISLSGGDPLHPQNVPDILKLVQRIRAECPGKDIW
                     VWTGYKLDELNAAQMQVVDLINVLVDGKFVQDLKDPSLIWRGSSNQVVHHLR"
     gene            complement(16349..16735)
                     /gene="cybC"
                     /locus_tag="RH288_000546"
     CDS             complement(16349..16735)
                     /gene="cybC"
                     /locus_tag="RH288_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HDV4029643.1"
                     /translation="MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVVEKADN
                     ATQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
                     EGKVKEAQAAAEQLKTTRNAYHQKYR"
     gene            complement(16790..18142)
                     /gene="pmbA"
                     /locus_tag="RH288_000547"
     CDS             complement(16790..18142)
                     /gene="pmbA"
                     /locus_tag="RH288_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HDV4029644.1"
                     /translation="MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFEAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEG
                     GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQT
                     PEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGAVYRKSTFL
                     LDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIRDGILTQWLLTSYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLSEMKIAGQ
                     "
     gene            18236..18787
                     /locus_tag="RH288_000548"
     CDS             18236..18787
                     /locus_tag="RH288_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HDV4029645.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     EIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            complement(18943..20316)
                     /gene="mpl"
                     /locus_tag="RH288_000549"
     CDS             complement(18943..20316)
                     /gene="mpl"
                     /locus_tag="RH288_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HDV4029646.1"
                     /translation="MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEK
                     QGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESDFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLV
                     GEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHI
                     PWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKAEAAQ"
     gene            20492..21490
                     /gene="fbp"
                     /locus_tag="RH288_000550"
     CDS             20492..21490
                     /gene="fbp"
                     /locus_tag="RH288_000550"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HDV4029647.1"
                     /translation="MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERLIREFPDA"
     gene            complement(21523..22518)
                     /gene="yjfF"
                     /locus_tag="RH288_000551"
     CDS             complement(21523..22518)
                     /gene="yjfF"
                     /locus_tag="RH288_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease YjfF"
                     /protein_id="HDV4029648.1"
                     /translation="MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAF
                     LGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFG
                     AFMGLLIDALKIPAFIITLAGMFFLRGVSYLVSEESIPINHPIYDTLSSLAWKIPGGG
                     RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLST
                     GLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQG
                     LIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIAQR"
     gene            complement(22505..23527)
                     /locus_tag="RH288_000552"
     CDS             complement(22505..23527)
                     /locus_tag="RH288_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4029649.1"
                     /translation="MPQSLPDTTPPKRRFRWPTGMPQLAALLLVLLVDSLVAPHFWQV
                     VLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVA
                     GFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITSGQIVT
                     FNSPDLSWFGSGSLLFLPTPVIIAVLTLILFWLLTRKTALGMFIEAVGINIRAAKNAG
                     VNTRIIVMLTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMG
                     GRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGV
                     RSRDKT"
     gene            complement(23541..25043)
                     /locus_tag="RH288_000553"
     CDS             complement(23541..25043)
                     /locus_tag="RH288_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDV4029650.1"
                     /translation="MTTNQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGEN
                     GAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAHAQQLGIGTVYQEVNLLPNMSVA
                     DNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAI
                     DLSAKVLILDEPTASLDTQEVELLFDLMRQLRDRGVSLIFVTHFLDQVYQVSDRITVL
                     RNGSFVGCRETCELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI
                     APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIKGKPQNLRSPHQASV
                     LGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQLGIR
                     TPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCA
                     DGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA"
     gene            complement(25183..26139)
                     /gene="ytfQ"
                     /locus_tag="RH288_000554"
     CDS             complement(25183..26139)
                     /gene="ytfQ"
                     /locus_tag="RH288_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter
                     substrate-binding protein YtfQ"
                     /protein_id="HDV4029651.1"
                     /translation="MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNV
                     AKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKD
                     AEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
                     ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYA
                     HNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMIDGEANASVELTPNMAGPA
                     FDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY"
     gene            26449..26979
                     /gene="ppa"
                     /locus_tag="RH288_000555"
     CDS             26449..26979
                     /gene="ppa"
                     /locus_tag="RH288_000555"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HDV4029652.1"
                     /translation="MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGE
                     DAKLIAVPHTKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
                     AAKAEIVASFERAKNK"
     gene            complement(27359..27700)
                     /locus_tag="RH288_000556"
     CDS             complement(27359..27700)
                     /locus_tag="RH288_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HDV4029653.1"
                     /translation="MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGA
                     VPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKL
                     IESGDWLDRDK"
     gene            complement(27703..31482)
                     /gene="tamB"
                     /locus_tag="RH288_000557"
     CDS             complement(27703..31482)
                     /gene="tamB"
                     /locus_tag="RH288_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HDV4029654.1"
                     /translation="MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAADRWVP
                     GLDVGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLAVGLECLWNSSVCINDLALKDIQ
                     VNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
                     LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPEEKPLGETLKDLFSR
                     PVLPEMTDVHLPLNLNIEEFKGEQLRVTGDTDITVRTMLLKVSSIDGNTKLDALDIDS
                     SQGIVNASGTAQLSDNWPVDITLNSTLNVEPLKGEKVKLKVGGALREQLEIGVNLSGP
                     VDMDLRAQTRLAEAGLPLNVEVNSKQIYWPFTGEKQYQADDLKLKLTGKMTDYTLSMR
                     TAVKGLEIPPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTL
                     NGINTAKEIPEWPSKLNGLIKTRGSLYGGTWQMEVPELKLTGNVKQNKVNVDGTLKGN
                     SYMQWMIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTAKGLVKV
                     RGTVEAPQLLADITARGLRWQELSVAQVRVEGDIKSTDQIAGKLDVRVEQISQPDVNI
                     NLVTLNAKGSEKQHELQLRIQGEPVSGQLNLAGSFDRKEERWKGTLSNTRFQTPVGPW
                     SLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLK
                     PFMPETTQASGIFTGKADVAWDTTKEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTL
                     NLTAELRNNRAELGWTIRLTNNGQFDGQVQVTDPQGRRNLGGNVNIRNFNLAMINPIF
                     TRGEKAAGMVSANLRLGGDVQSPQLFGQLQVTGVDIDGNFMPFDMQPSQLAVNFNGMR
                     STLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPMVRMDVSPDVVFE
                     ATPNLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNDNLQPEEPKTASIPINSNL
                     IVHVGNNVRIDAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGE
                     LLFSGPPDQPYLNIEAIRNPDATEDDVIAGVRVTGLADEPKAEIFSDPAMSQQAALSY
                     LLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            complement(31479..33212)
                     /gene="tamA"
                     /locus_tag="RH288_000558"
     CDS             complement(31479..33212)
                     /gene="tamA"
                     /locus_tag="RH288_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HDV4029655.1"
                     /translation="MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLS
                     TIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGV
                     PVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
                     SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPQFDKARETKVLPLTGVVSPRTENTIETGVGYST
                     DVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQILDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRGT
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSIAPKYANGDLKGASKLITGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVADKDEHG
                     LQFYIGLGPEL"
     gene            33418..34056
                     /gene="msrA"
                     /locus_tag="RH288_000559"
     CDS             33418..34056
                     /gene="msrA"
                     /locus_tag="RH288_000559"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDV4029656.1"
                     /translation="MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGME
                     IAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYD
                     PSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
                     MLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA"
     gene            34379..35722
                     /locus_tag="RH288_000560"
     CDS             34379..35722
                     /locus_tag="RH288_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDV4029657.1"
                     /translation="MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINA
                     QRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSF
                     ILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANI
                     IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTP
                     RENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA"
     gene            complement(35784..35990)
                     /locus_tag="RH288_000561"
     CDS             complement(35784..35990)
                     /locus_tag="RH288_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HDV4029658.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     KDKLHLSVMSEVNRQVMRLQTEMA"
     gene            36315..36872
                     /locus_tag="RH288_000562"
     CDS             36315..36872
                     /locus_tag="RH288_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HDV4029659.1"
                     /translation="MTLRKILALTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDK
                     DQFSYKTWNSAQLVGKVRVLQHIAGRTSAKEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEESSAVVVLDKDGRVQ
                     WAKDGALTQEEVQQVMDLLHKLINK"
     gene            complement(36862..37602)
                     /gene="cysQ"
                     /locus_tag="RH288_000563"
     CDS             complement(36862..37602)
                     /gene="cysQ"
                     /locus_tag="RH288_000563"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HDV4029660.1"
                     /translation="MLDQVCQLARNAGDAIMQVYDGTKPMDVVSKADNSPVTAADIAA
                     HTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIDHGKPILGVVYAPVMNIMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
                     AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGA
                     HVHDWQGKPLDYTPRESFLNPGFRVSIY"
     gene            37792..39735
                     /gene="cpdB"
                     /locus_tag="RH288_000564"
     CDS             37792..39735
                     /gene="cpdB"
                     /locus_tag="RH288_000564"
                     /EC_number="3.1.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2',3'-cyclic-nucleotide 2'-phosphodiesterase"
                     /protein_id="HDV4029661.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYISAKGLKAGDVHPVYK
                     ALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDT
                     EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGAD
                     VVVVLAHSGLSADPYKVMAENSVYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIA
                     KGTLNGVPAVMPGMWGDHLGVVDLQLSNNSGKWQVTQAKAEARPIYDIANKKSLAAED
                     SKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKAS
                     GKEVKEWLECSAGQFNQIDPDNTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYD
                     GECQMVNANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKG
                     QYPMNKVATDDIGFAIYQVDLSK"
     gene            complement(39858..40238)
                     /locus_tag="RH288_000565"
     CDS             complement(39858..40238)
                     /locus_tag="RH288_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDV4029662.1"
                     /translation="MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREG
                     THRFSDLRRKIGGVSEKMLAQSLQALEQDGFLNRIAYPVVPPHVEYSLTPLGEQVSEK
                     VAALADWIELNLPEVLAVRDERAA"
     gene            40327..41187
                     /gene="qorB"
                     /locus_tag="RH288_000566"
     CDS             40327..41187
                     /gene="qorB"
                     /locus_tag="RH288_000566"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001491469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HDV4029663.1"
                     /translation="MIAITGATGQLGHYVIKSLMKTVPASQIVAIVRNPAKAQALTAQ
                     GITVRQADYGDEAALTSALQGVEKLLLISSSEVGQRAPQHRNVINAAKTAGVKFIAYT
                     SLLHADKSPLGLADEHIETEKMLADSGIVYTLLRNGWYTENYLASAPAALEHGVFIGA
                     AGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKQVT
                     YQNLSETDFAAALKSVGLPDGLADMLADSDVGASKGGLFDDSKTLSKLIGRPTTTLAE
                     SVSHLFNVNK"
     gene            41296..42261
                     /locus_tag="RH288_000567"
     CDS             41296..42261
                     /locus_tag="RH288_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709987.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV4029664.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLI
                     ALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLP
                     VVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLACVNIAELNHGLPDFDWARYTSGI
                     VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNIQ
                     TPDFSLPFGPRPLVFISLMVAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGL
                     LYTFLIRQQMPPLMTLSGIALLVVGVVIAVRAKPEKPLTESVSES"
     gene            42369..43031
                     /gene="ytfE"
                     /locus_tag="RH288_000568"
     CDS             42369..43031
                     /gene="ytfE"
                     /locus_tag="RH288_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HDV4029665.1"
                     /translation="MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARK
                     ELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
                     RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
                     DEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALA
                     GE"
     gene            complement(43076..44488)
                     /gene="cycA"
                     /locus_tag="RH288_000569"
                     /gene_synonym="dagA"
     CDS             complement(43076..44488)
                     /gene="cycA"
                     /locus_tag="RH288_000569"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HDV4029666.1"
                     /translation="MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEM
                     EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWF
                     IALGLGWLFIGKKRAAELRK"
     gene            complement(44797..45417)
                     /gene="fklB"
                     /locus_tag="RH288_000570"
     CDS             complement(44797..45417)
                     /gene="fklB"
                     /locus_tag="RH288_000570"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDV4029667.1"
                     /translation="MTTPTFDTIEAQASYGIGLQVGQQLSESGLQGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTES
                     GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            45636..46274
                     /gene="ytfB"
                     /locus_tag="RH288_000571"
     CDS             45636..46274
                     /gene="ytfB"
                     /locus_tag="RH288_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418627.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YtfB"
                     /protein_id="HDV4029668.1"
                     /translation="MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIILVV
                     GFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLRAQLVTPQNDPDQVAPVAPEPIQ
                     EGQPEEQPQTTQTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVE
                     GAGKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR"
     gene            complement(46258..46905)
                     /locus_tag="RH288_000572"
     CDS             complement(46258..46905)
                     /locus_tag="RH288_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709992.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDV4029669.1"
                     /translation="MYLDTSNVQSLKEKLLLCAVNEFAEYGYEGARVDNIVKAAGCSK
                     QTVYHHFGNKENLFIEVLEYTWNDIRQKEKALDFSDLPPQKAIEKIIDFTWDYYITNP
                     WFLKIVHSENQSKGVHYAKSQRLLEINHAHLQLMESLLDEGKKHNIFKPDIDPLQVNI
                     NIAALGGYYLINQHTLGLVYHISMVSPQALEARRKVIKETILSWLLVDPSSTAHE"
     gene            47118..47909
                     /locus_tag="RH288_000573"
     CDS             47118..47909
                     /locus_tag="RH288_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="HDV4029670.1"
                     /translation="MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDLPDADSVE
                     KLHITQQECIAEGVEVICFPADVGDLSLHEEMLDAAQNLWGRLDCLLNNAGISVKKRG
                     DLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
                     AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAK
                     GLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLSMPRF"
     gene            47919..48761
                     /locus_tag="RH288_000574"
     CDS             47919..48761
                     /locus_tag="RH288_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDV4029671.1"
                     /translation="MRDLLQRPDLFSINTATLGYKTPLPAIIDACAARGIGAIAPWRR
                     ELQGEDLQQIARQLAASNMSVSGLCRSTYYTAPTLAERKLAIDDNRRALDDAAVLNAA
                     CYMQVVGGLPQGTKDLYEAREQVKQGIRQLLPHSKDVGVPIALEPLHPMTAADRSCLC
                     TLRQALDWCDELDPDGEFGLGVAVDVYHVWWDPELASQILRAGKRILAFHVSDWLVPT
                     TDLVNDRGMPGDGVINIPSIRRLVENAGFNGAIELEIFSPYWWQKDINSTLDISVDRI
                     AHYC"
     gene            48771..49547
                     /locus_tag="RH288_000575"
     CDS             48771..49547
                     /locus_tag="RH288_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDV4029672.1"
                     /translation="MSDQPVLFSRAAASCRLTLNREDKCHAINEEMIESLDHYLNEIE
                     NDTTLRLVELTATGDKFFCAGGDIKSWSAYSPLDMGRKWIKRGNDVFNRLRNLPQLTV
                     ANLNGHTIGGGIELALCCDIRIARPGAKFSNPEVMLGMVPGWMGIERVLNQVGPVVGR
                     QMLMLGKRLTAQEAQAANLIDEVVEKEQVESWMANQLAQLEKCGPVALAHIKQLILAL
                     ENKHADYPHQLLAGLMSATQDCQQATRAFAEKSSVSFHNQ"
     gene            49557..51098
                     /locus_tag="RH288_000576"
     CDS             49557..51098
                     /locus_tag="RH288_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDV4029673.1"
                     /translation="MRKITTAEALAAQIQDGATIAISGNGGGMVEADHILAAIEARFL
                     QTGHPRDLTLIHSLGIGDRDCKGTNRFAHAEMLKRIIAGHFTWSPKMQALVKNNTIEA
                     YCFPGGVIQALLREIGAGRPGLFTHVGLGSFVDPRNGGGKSNECTTDDLVELIEIDGE
                     TKLRYRPFKVDYAILRGTYADPRGNVSLEEEAIDMDSYSMALAAHNSGGKVFVQVRDV
                     LEAGAIEPRRVKLPGILVDGIVEHREQPQTYLGGYDLTISGQHRRLSSNDAIELVSHP
                     VRRLIARRAARELVAGASTNFGFGIPGGIPGVALREGVPYQSLWLSVEQGVHNGMMLD
                     DALFGCARNADAIIPSLDQFEFYSGGGIDITFLGMGEMDQYGNVNVSHLNGNLIGPGG
                     FLEIAQNARKVVFCGTFDAKGSKIDVTPDGLHIAQSGQIPKLVTQVEKITFSAAYAQQ
                     SGQEVLYITERAVFQLTAEGVELIEIAPSVEIERDILPYMAFRPIIKHPRLMESSLFT
                     PMEDA"
     gene            51095..53167
                     /locus_tag="RH288_000577"
     CDS             51095..53167
                     /locus_tag="RH288_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDV4029674.1"
                     /translation="MSQLDDTILDALTHVTFPKGFAQAEPAWVVTVDGVDYPLWQTDA
                     LVVGSGAAGLRAAVELKRRQQNVLIATAGLYMGTSACSGSDKQTLFTAATAGNGDNFT
                     KLAEALASGGAMDHDTAYVEAVGSLHTLGGLQYLGLELPEDRYGAILRYQTDHDEAGR
                     ATSCGPRTSRLMVKVLLEEVQRLAIPVLTSATVIKLLHQRDENGEDRVAGAILATGHR
                     AHNPWGLAIVTAPNVVLATGGPGELYRDSVYPHKCFGSLGLALEEGLTLTNLTESQFG
                     IGTPRSTFPWNLSGTYVQVIPYIYSVDAEGNEYNFLADYYRTTQELASNIFRKGYQWP
                     FHATRVMDFGSSLLDMAVAQEQQSGRQVFMDFNRNPEPVPGDLPFSLERLDDDVRAYL
                     ENNDALAPSPIERLQRMNPLSISLYKMHGYDLTTQPLQFAMNNQHMNGGIEVDIWGQT
                     SLPGCFAVGEVAGTHGITRPGGAALNAGQVFAVRLARFIGCTQKRNIDGDIAQLVAQA
                     LASIREIITQAHDNGTGMPLSVVREKIQARMSDHAGFICHADKVRRATRDALLLNEFV
                     QRHGLAIKHVGEVAELFMWRHMALTSAAVLTQLTHYIDAGGGSRGARIVIDPQGKCLP
                     QTRRGAKEEWRFRSERAEDKNHRLTIQYSQGSFITEVKSLRMQPCINGIYFEKNWPDF
                     LNGEIYTQ"
     gene            53260..54537
                     /locus_tag="RH288_000578"
     CDS             53260..54537
                     /locus_tag="RH288_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4029675.1"
                     /translation="MNKIKNYRWHMIALVCFITVINYLDRTALGIAAPTIMETTGITK
                     EQYSWIVSAFQLAYTLGQPVMGFFIDTVGLKLSFAICAAIWGLATMGHALTGTWSGLA
                     FMRALMGFSEASAIPAGVKTASTWFPAKERGVATGVFNMGTSLGAMLAPPLIAWCIMF
                     HSWQFAFIVSGSLALLAALFWFFCYKDPKDAKRLSDEERHYIESGQEQHLKTDKKEKT
                     SIKHILSQRNFWGIGIARFLADPAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLLG
                     DLGCLASGFVAKFFHDRGVSLINSRRITFTIAAVIMMTIGLVSIVENPYIAVLLISIG
                     AFSHQCLSTVAATLGGDLFKKDEVATAVGMAGACAWSGQLIFNLFIGAFVHIIGFAPF
                     FIALAFFDIIGAIALWTLIKVKDEEPQVQLATS"
     gene            complement(54639..55088)
                     /gene="rplI"
                     /locus_tag="RH288_000579"
     CDS             complement(54639..55088)
                     /gene="rplI"
                     /locus_tag="RH288_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDV4029676.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNI
                     EFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE"
     gene            complement(55130..55357)
                     /gene="rpsR"
                     /locus_tag="RH288_000580"
     CDS             complement(55130..55357)
                     /gene="rpsR"
                     /locus_tag="RH288_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDV4029677.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            complement(55362..55676)
                     /gene="priB"
                     /locus_tag="RH288_000581"
     CDS             complement(55362..55676)
                     /gene="priB"
                     /locus_tag="RH288_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HDV4029678.1"
                     /translation="MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            complement(55683..56078)
                     /gene="rpsF"
                     /locus_tag="RH288_000582"
     CDS             complement(55683..56078)
                     /gene="rpsF"
                     /locus_tag="RH288_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDV4029679.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            56405..56680
                     /locus_tag="RH288_000583"
     CDS             56405..56680
                     /locus_tag="RH288_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV4029680.1"
                     /translation="MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYIN
                     HNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR"
     gene            complement(56809..57495)
                     /gene="ulaF"
                     /locus_tag="RH288_000584"
     CDS             complement(56809..57495)
                     /gene="ulaF"
                     /locus_tag="RH288_000584"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase UlaF"
                     /protein_id="HDV4029681.1"
                     /translation="MQKLKQQVFEANMELPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKAADMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAW
                     AQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGNAEPLHTP
                     GIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(57495..58349)
                     /gene="ulaE"
                     /locus_tag="RH288_000585"
     CDS             complement(57495..58349)
                     /gene="ulaE"
                     /locus_tag="RH288_000585"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HDV4029682.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETD
                     ERLSRLDWSRDQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMA
                     KAGMVEAA"
     gene            complement(58359..59009)
                     /gene="ulaD"
                     /locus_tag="RH288_000586"
     CDS             complement(58359..59009)
                     /gene="ulaD"
                     /locus_tag="RH288_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDV4029683.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG"
     gene            complement(59023..59487)
                     /gene="ulaC"
                     /locus_tag="RH288_000587"
     CDS             complement(59023..59487)
                     /gene="ulaC"
                     /locus_tag="RH288_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HDV4029684.1"
                     /translation="MKLRDSLAENKSIRLQAEAETWQDAVKIGVDLLVAADVVEPRYY
                     QAILDAVEQHGPYFVLAPGLAMPHGRPEEGVKKTGFALVTLKKPLEFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA"
     gene            complement(59497..59802)
                     /gene="ulaB"
                     /locus_tag="RH288_000588"
     CDS             complement(59497..59802)
                     /gene="ulaB"
                     /locus_tag="RH288_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HDV4029685.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEY
                     KSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK"
     gene            complement(59818..61215)
                     /gene="ulaA"
                     /locus_tag="RH288_000589"
     CDS             complement(59818..61215)
                     /gene="ulaA"
                     /locus_tag="RH288_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDV4029686.1"
                     /translation="MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIERMGDAYS
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
                     CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQTMAGKVNWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRAL
                     RAEEDAEKQLAEQSA"
     gene            61570..62634
                     /gene="ulaG"
                     /locus_tag="RH288_000590"
     CDS             61570..62634
                     /gene="ulaG"
                     /locus_tag="RH288_000590"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDV4029687.1"
                     /translation="MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLG
                     CTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQVDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPG
                     GSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
     gene            62742..63497
                     /gene="ulaR"
                     /locus_tag="RH288_000591"
     CDS             62742..63497
                     /gene="ulaR"
                     /locus_tag="RH288_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HDV4029688.1"
                     /translation="MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLF
                     SRADQIDMLITGKNANPEILQQLEAQGVSILRV"
     gene            complement(63494..64243)
                     /gene="yjfP"
                     /locus_tag="RH288_000592"
     CDS             complement(63494..64243)
                     /gene="yjfP"
                     /locus_tag="RH288_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDV4029689.1"
                     /translation="MIEIESRELADIPVLHAYPVGQKDTPLPCAIFYHGFTSSSLVYS
                     YFAVALAQAGLRVIMPDAPDHGSRFSGDAARRLNQFWQILLQSMQEFTTLRAAIAEEK
                     WLLDDRLAVGGASMGAMTALGITARHPTVRCTASMMGSGYFTSLARSLFPPLIPETTA
                     QQNEFNNIVAPLAEWEATNHLEQLSDRPLLLWHGLDDDVVPADESLRLQQALSETGRD
                     KLLTCSWQPGVRHRITPEALDAAVTFFRQHL"
     gene            64425..64754
                     /gene="bsmA"
                     /locus_tag="RH288_000593"
     CDS             64425..64754
                     /gene="bsmA"
                     /locus_tag="RH288_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418610.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HDV4029690.1"
                     /translation="MVSRKRNSVIYRFASLLLVLMLSACSALQGTPQPAPPVTDHPQE
                     IRRDQTQGLQRIGSVSTMVRGSPDDALAEIKAKAVAAKADYYVVVMVDETIVTGQWYS
                     QAILYRK"
     gene            64903..65178
                     /gene="yjfN"
                     /locus_tag="RH288_000594"
     CDS             64903..65178
                     /gene="yjfN"
                     /locus_tag="RH288_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418609.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease activator YjfN"
                     /protein_id="HDV4029691.1"
                     /translation="MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVS
                     NISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA"
     gene            complement(65295..66920)
                     /locus_tag="RH288_000595"
     CDS             complement(65295..66920)
                     /locus_tag="RH288_000595"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418608.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HDV4029692.1"
                     /translation="MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLA
                     SIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHN
                     LAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPL
                     LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS
                     VPQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA
                     IGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQ
                     PLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPF
                     VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLS
                     EAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQ
                     AWCQVMLDTRGGVRLSEEIQNDLLLRATGGVCV"
     gene            complement(67004..68167)
                     /locus_tag="RH288_000596"
     CDS             complement(67004..68167)
                     /locus_tag="RH288_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HDV4029693.1"
                     /translation="MLRHNVPVRRDLDQIAADNGFDFHIIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIPPLYWDVIAESWRARDPSLYGRM
                     DFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGIIPRDADQYNAIQERLI
                     SRFSELYSREPFYFCCCQDTDEDRSTVLYLQDCAQQAGQESRFIYIEDLGLGVGGVLT
                     DLDDNVIQRAFKLYPLEGMMRDDNGPLLRKRREQWVEPLWKSILSNKGLMPLLWRFFP
                     GHPNLLASWFEGEKSQIAAGESYVRKPLYSREGGNVTIFDGQNNVVDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG"
     gene            complement(68170..68808)
                     /locus_tag="RH288_000597"
     CDS             complement(68170..68808)
                     /locus_tag="RH288_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HDV4029694.1"
                     /translation="MARKRKSRNNSKIGHGAISRIGRPNNPFEPRRNRYAQKYLTLAL
                     MGGAAFFVLKGCSDSSDVDNDGDGTFYATVQDCIDDGNNADICARGWNNAKTAFYADV
                     PKNMTQQNCQSKYENCYYDNVEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASR
                     PVWRSTSGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG"
     gene            complement(68818..69216)
                     /locus_tag="RH288_000598"
     CDS             complement(68818..69216)
                     /locus_tag="RH288_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HDV4029695.1"
                     /translation="MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNN
                     TAASLAFSGTLLGYVIPLSSAAINAVSIPDYFAWGGIALVIQLLVFAGVRLYMPALSE
                     KIINHNTAAGMFMGTAALAGGIFNAACMTW"
     gene            complement(69234..69893)
                     /locus_tag="RH288_000599"
     CDS             complement(69234..69893)
                     /locus_tag="RH288_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HDV4029696.1"
                     /translation="MSGFFQRLFGKDNKPAIARGPLGLHLNSGFTLDTLAFRLLEDEL
                     LIALPGEEFTVAAVSHIDLGGGSQIFRYYTSGDEFLQINTTGGEDIDDIDDIKLFVYE
                     ESYGISKESHWREAINAKAMGAMTLNWQEKRWQRFFNSEEPGNIEPVYMLEKVENQNH
                     AKWEVHNFTMGYQRQVTEDTYEYLLLNGEESFNDLGEPEWLFSRALGVDIPLTSLHII
                     G"
     gene            complement(69944..70642)
                     /locus_tag="RH288_000600"
     CDS             complement(69944..70642)
                     /locus_tag="RH288_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
                     /protein_id="HDV4029697.1"
                     /translation="MGILKSLFTLGKSFISQAEESIEETQGVRMLEQHIRDAKAELDK
                     AGKSRVDLLARVKLSHDKLKDLRERKASLEARALEALSKNVNPSLINEVAEEIARLEN
                     LITAEEQVLSNLEVSRDGVEKAVTATAQRIAQFEQQMEVVKATEAMQRAQQAVTTSTV
                     GASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDEKLAEAGIGGSNKSS
                     AQDVLARLQRQQGE"
     gene            complement(70661..>71035)
                     /locus_tag="RH288_000601"
     CDS             complement(70661..>71035)
                     /locus_tag="RH288_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 family protein"
                     /protein_id="HDV4029698.1"
                     /translation="TALQTVPEQNIDVTNSENALIIKMNDYGDLQINILFTSRQMIIE
                     TFICPVSSISNPDEFNTFLLRNQKMMPLSSVGISSVQQEEYYIVFGALSLKSSLEDIL
                     LEITSLVDNALDLAEITEEYSH"
BASE COUNT        17518 a        18772 c        17703 g        17042 t
ORIGIN      
        1 ctttcagtat ccctttttca ccaagcaagt atgaaatcga ttcattacat acataaggca
       61 ttaatagcag atgttctttc cttattgcta ataatgcatt attcaatggt ttttctaata
      121 aatccgtaat cgtagaatca actgaatctt tacaactcac ctgcgagtta ttcaagtcct
      181 gagaattatt taactcctgc ggaatattta atagacgagc tatttccttg ttagcttcgc
      241 gttggtaaca cgccagaatc ttgttagtaa tcaggtgtaa tgaactctca tcttttcttt
      301 caaaggactt cccttcataa cgattagtcg aaccatcagg ttgtggaaat ataatgactg
      361 tatgtccttc acgaatccca ttattaaaag ctgaggcaag tgtaatttct atttccacct
      421 tagataaatc cgctcgctcc ccttcaggat tattcataac aaacttcatt atctcactac
      481 catcattatt tttgatataa gatgaggact taatatgagc catcatattt ctacccgctt
      541 cgttggagcg tttgctaaaa tccacataac ccagggtaaa tatcttagcc aaaaactcca
      601 aaaatgctct gggagaaaga atattgcttc tgctattctg ccctccggca attcgggcaa
      661 aatcattcat tcccacatac caggtatcta agtcttcatt tttttgttta caattgtcgg
      721 ctgatgtaat gttttgagaa aaattccaac ctgatatttt gctcatgacg gactccttga
      781 gttaataaga acgtctaagc attacaaatt ttactcacaa aaaaatatca aaaaacgctc
      841 ttttcacaaa ctcgccgtaa acctggagtt atttacggcg aaaagtcatc acgccatcag
      901 catcttcact actgctttgc gaacctgggc tggtgcaccc actgcgcaca gcggtttatg
      961 cacttccccc ggataaaaca caacaaaatc accttcatta aggataactg ttttctcatc
     1021 aacgccttcc ggcaaaaatg cgatgtcttt atcagctaac cagtcggtat ccggcgtgcc
     1081 tgcaggttgc gtgctgaagg tcatgccttc ctgacctttt aacacaatct gaatgtcgag
     1141 atagcgggca tggtactccg cacggcgggc ttcgtacggc tcggtcatat cttccgagat
     1201 aagataaaac agacgattgc cttcgatatc gtgcttgccc tttggcgttt ctgccgtaac
     1261 gtgtgctttg atatgctcaa tcgcctggcg taactcctgg ggtagccacg gctgaagatt
     1321 atgaatattt ccgatgatca tcttttccac tccttaatta aaacaacgtt tcatttctat
     1381 cgttatacga aaagatgatc aattccgcta gccttaacgc gtgaattatt gtcttatcac
     1441 aacttatcgg caggcgcgtt cccgcctttc ggatcaaggc cagcatcact ccttgagaag
     1501 agtttttatc gcttcccccg ccagtgcagc tgttgcacag agttgttcga ttgagtgccc
     1561 ctcccgtgcc ttcgcagaaa gccctgacat cacggtactc ataaaatcag tcacacattg
     1621 tgcgctttgt ggatgccgcc tggcgatata gtcataaatg gtcgtttctg cggcgtgata
     1681 atattgaacg gcaatatcac gcgctagtgg atcatgacta tgaatacctt caagaaccat
     1741 acagccagcg cagccgccat tttggctata tctgcgcgcc gcttctttta atacctcaac
     1801 caggcactcg cctactggac gatcatcacg aagaatatcg gcaagcggaa tagcttccgt
     1861 accgacgtat tcattgagta cacggctaaa taacccagct ttactgccaa aagccgcgta
     1921 gaggctcggg gggttaatac caagataatc agtaacttca gcaacactga cagcatcgaa
     1981 acctttttgg tgaaaaagca cttttgccgc agagactgcc tgctcaggag cgaaacgtct
     2041 gggacgacct ggaacgcgag attgtttttt agtgaccatt acaaaacttg ttgacagaaa
     2101 gttaaaacag ttttgtaatg catgttacat aataaatcaa ggagtcctta tgggcgcttt
     2161 tacaggtaag acagttctca tcctcggtgg cagccgtgga atcggtgccg ctatggtacg
     2221 tcgtttcgtc accgatgggg ccaatgtacg attcacctat gcggggtcga aagatgccgc
     2281 tgaacacctg gcacaagaga ctggagcgac agcagtattc acagatagtg ctgacagaga
     2341 cgctgtcatt gatgtcgttc gtaagagtgg cgcattggat attctggtag taaatgcagg
     2401 tattggcgtc tttggcgatg ccctggaatt aaatgccgac gatattgatc gccttttcaa
     2461 aatcaatatt catgctcctt atcatgcctc tgttgaagcc gcccggcaga tgcccgaagg
     2521 cgggcgcatc ttaatcatcg gctccgtgaa tggcgatcgt atgcctgttg caggcatggc
     2581 tgcttatgcc gccagcaaat ctgccctgca aggcatggcg cgcgggctgg cccgtgattt
     2641 tggaccgcgt gggatcacca ttaacgtcgt ccagccaggg ccaattgata ccgacgctaa
     2701 tcccgccaac gggccaatgc gcgatatgtt gcatggtttt atggccatca aaagacatgg
     2761 gcaaccggaa gaggtcgctg gtatggtcgc atggttagca gggccagaag ccagttttgt
     2821 taccggcgcg atgcatacca ttgatggcgc gtttggcgca taaccgacta cgctcaatta
     2881 agcccagcca ttatccatga tgtctgggtt ttgtttactc acgtcgtccg ctaaaagcgg
     2941 ctcccggtaa agagaaatct tctgttcatg tcgtaaatct tgaggataac caaatggtag
     3001 aaagaaccgc tgttttccct gctggccgac attcactata tgctgagcat cgttattctg
     3061 cggctattcg ttccggcgat ttgctgtttg tttccgggca agtaggaagt cgagaggacg
     3121 gaacaccaga acccgatttt cagcaacaag tcagactggc atttgataat ttgcatgcga
     3181 ccctggcagt tgcgggatgc acttttgacg atatcattga tgttacgagc ttccataccg
     3241 atccagaaaa ccaatttgaa gacatcatga cggtgaaaaa tgaaatattt agcgccccac
     3301 cttatccaaa ctggacggcg gtgggtgtta catggctggc aggctttgat tttgaaatta
     3361 aagtgatagc gcgcatccct gagcagtaag caatagtgtt agccgttcgc tttcacactc
     3421 cgccctataa gtcggatgaa tggaataaaa tgcatatctg attgcgtgaa agtgaaaaag
     3481 aaaaaagcag ggaatgtctg caattattga taccgaacga cagttcccct gcagaatcac
     3541 atcaaataaa aatgcatata ccttgacttt taattcaaat aaaccgtttg cgctgacaaa
     3601 atattgcatc aaatgcttgc gccgcttctg acgatgagta taatgccgga caatttgccg
     3661 ggaggatgta tggttcagtg tgttcgacat tttgtcttac cgcgtctgaa aaaagacgct
     3721 ggcctgccgt ttttcttccc gttgatcacc cattcccagc ccctcaatcg aggggctttt
     3781 ttttgcccag gcgtcaggag ataaaagatg gctaatccgc tatatcagaa acatatcatt
     3841 tccataaacg accttagtcg cgatgacctt aatctggtgc tggcgacagc ggcgaaactg
     3901 aaagcaaacc cgcaaccaga gctgttgaag cacaaagtca ttgccagctg tttcttcgaa
     3961 gcctctaccc gtacccgcct ctctttcgaa acatctatgc accgcctggg tgccagcgtg
     4021 gtgggcttct ccgacagcgc caatacatca ctgggtaaaa agggcgaaac gctggccgat
     4081 accatttcgg ttatcagcac ttacgtcgat gcgatagtga tgcgtcatcc gcaggaaggt
     4141 gcggcgcgcc tggccaccga gttttccggc aatgtaccgg tactgaatgc cggtgatggc
     4201 tccaaccaac atccgacgca aaccttgctg gacttattca ctattcagga aacccagggg
     4261 cgtctggaca atctccacgt cgcaatggtt ggtgacctga aatatggccg caccgttcac
     4321 tccctgactc aggcgttagc gaagttcgac ggcaaccgtt tttacttcat cgcgccggac
     4381 gcgctggcaa tgccgcaata cattctggat atgctcgatg aaaaagggat cgcatggagt
     4441 ctgcacagct ctattgaaga agtgatggcg gaagtagaca tcctgtacat gacccgcgtg
     4501 caaaaagagc gtctggaccc gtccgagtac gccaacgtga aagcgcagtt tgttcttcgc
     4561 gccagcgatc tccacaacgc caaagccaat atgaaagtgc tgcatccgct gccgcgtgtt
     4621 gatgagattg cgacggatgt tgataaaacg ccacacgcct ggtacttcca gcaggcaggc
     4681 aacgggattt tcgctcgcca ggcgttactg gcactggttc tgaatcgcga tctggtactg
     4741 taaggggaaa tagagatgac acacgataat aaattgcagg ttgaagctat taaacgcggc
     4801 acggtaattg accatatccc cgcccagatc ggttttaagc tgttgagtct gttcaagctg
     4861 accgaaacgg atcagcggat caccattggt ctgaacctgc cttctggcga gatgggccgc
     4921 aaagatctga tcaaaatcga aaataccttt ttgagtgaag atcaggtaga tcaactggca
     4981 ttgtatgcac cgcaagccac ggttaaccgt atcgacaact atgaagtggt gggtaaatcg
     5041 cgccccagtc tgccggagcg catcgacaac gtgctggtct gcccgaacag caactgtatc
     5101 agccatgccg aaccggtttc ttccagcttt gccgtgcgaa aacgcgccaa tgacatcgcg
     5161 ctcaaatgca aatactgtga aaaagagttt tcccataatg tggtgctggc caattaattg
     5221 cggttggtaa taaaagtctg gctccctata atgagccaga ctttttaccg ctgtaataaa
     5281 ggagaaatca tgagcaaaac tatcgcgacg gaaaatgcac cggcagctat cggtccttac
     5341 gtacagggcg ttgatctggg caatatgatc atcacctccg gtcagatccc ggtaaatccg
     5401 aaaacgggtg aagtaccggc agacgtcgct gcacaggcac gtcagtcgct ggataacgta
     5461 aaagcgattg tcgaagccgc tggcctgaaa gtgggcgata tcgttaaaac caccgtgttt
     5521 gtgaaagatc tgaacgactt cgctaccgtt aatgctacct acgaagcctt cttcaccgaa
     5581 cacaacgcca ccttcccggc acgttcttgc gttgaagtcg cccgtctgcc gaaagacgtg
     5641 aagattgaga tcgaagcgat cgctgttcgt cgctaatctt gatggaaatc cgggctatca
     5701 tgcccggatt aagtctgatg acaaacgcaa aatcgcctga tgcgctacgc ttatcaggcc
     5761 tacgtgattc ctgcaattta ttgaatttgt tggccggata aggcatttac gccgcatccg
     5821 gcatgaacaa agcttacttt gtctgcaatc tgaatcgggg ctatcgtgcc cagtttattc
     5881 tttattgcca gccgtaacga cggctataga accctttcac caactgggtt aatgtcatat
     5941 accctgccag aatcgcaacc agccacggga aatagcttaa cggcagcgcc tgtaattgca
     6001 gataactggc cagcggtgaa aacggcaatg cgatcccgac aatcatcacg atcacggtca
     6061 tgatcattaa cggccacgat gcacagctct gaataaacgg cacacggcgg gtgcggatca
     6121 tatgcacaat cagcgtttgc gacagtaagc ccaccacaaa ccatcccgac tggaacagcg
     6181 tttgcgtttc cggcgtgttg gcatggaata cccaccacat caggcaaaac gtcagaatat
     6241 cgaagatcga gctgatcggt ccgaagaaga tcataaagcg ccccagatcc gccggattcc
     6301 aacgctgcgg cttttgaatt tgctcgtcgt cgacgttatc aaacgggatc gccacctgtg
     6361 acacatcata cagcaggttc tgaataagca agtgtaacgg caacatcggc aggaagggca
     6421 agaaagcact cgccaccagc acgctgaaca cattaccgaa gttggagctc gccgtcattt
     6481 tgatgtattt cagcatgttg gcgaaagtgc gacgtccttc aataaccccc tcttccagca
     6541 ccatcaggct tttttccagc aggatgatat cagccgcttc acgggcaata tctaccgcgc
     6601 cgtccacaga aatgccgata tccgcagcgc gtaaggcggg cgcatcatta ataccatcgc
     6661 ccataaagcc aaccacatgc ccttcgcgct tcagtaaggt cacaatgcgt tctttatgca
     6721 tcggcgtcag acgagcaaac agcgtggtgc gctgtgcgag atttgccagt tcgtcgtcag
     6781 atagcgtttc aatatcacta ccaatgacca cctctcccgc gtccagcccc acttcatggc
     6841 acactttcgc tgcaactaac tcactgtcgc cagtaaggat ttttacggta attccactcg
     6901 cttttaatgc cttcagtgcc ggagcagttg tctcttttgg cggatcaagg aaagcaatat
     6961 atccttcgag gatcaggtcg gattcatccg cccgctggta atctccttca cgcgctggca
     7021 ggtatttcgt cgccaccgca accacgcgca gcccctgacg attcagcgta tcagtaaccc
     7081 gcttaatctt acgcagcatg atgtcatcga gcggcacaat ctcgccattg tgacgcacct
     7141 gcgaacacac attgaggatt tcctgcaatg cacctttgca aaccagctga tggtgctcgg
     7201 tattttctgc cactaccacc gacatccggc gacgctcgaa atcaaacgga atctcatcaa
     7261 ttttttgcca acggctggcc agcgagcgcg ctgactcttc atccgtacct tcgagcaccg
     7321 ctgtatcgag caggttttta agtccggtct gataatgact gttcaaccac gcgctatgca
     7381 gcacgcgttc gctggtttta ccggagatat cggtatgatt ctccagcaca attttgtcct
     7441 gtgtcagggt gccggtttta tcagtgcaca gaatatccat tgcgccaaag ttctgaatag
     7501 catccagatg tttgacgatc actttctgtt tcgacagctt tactgcgccg cgcgccagcg
     7561 tcgaggtaac aatcatcggc aacatttccg gcgttaagcc taccgcgacc gaaagcgcaa
     7621 acagtgccgc ttcccaccag tcgcctttgg tgtaaccgtt gataagcaac accaccggag
     7681 ccatcaccag cataaagcga atcagcagca tactgacgcg gctgatcccc tgctgaaagg
     7741 cattcggctc gctttcctgc tcactaacac gccccgccag ttgaccaaac caggtgttgg
     7801 ctcctgtagc aatcaccatt gcttgtgccg tgccgctcac cacggtggtg cccataaaac
     7861 acagggtatc gcactccagc ggattgctgt gctccggctg gcgagtggta gcggcttttt
     7921 ctacgggcag agactcaccg gttaacgacg cctgagcgac gaacagatcc cgcgcctgca
     7981 agatacgtaa atctgccggg atcatatctc ccgccgccag ttttataata tcgccgggca
     8041 ccagctggtc gatcgggatc tccagccagc cattttcgcc tttgtcgtta attacgcgca
     8101 gcaccgtcgc ggtattgctg accatcgctt tcagggcatc tgccgcttta gtggaacgtg
     8161 cttcctgaat aaagttcagc aacgttgaaa tagcgaccat tagcgcgata acgcccgcgg
     8221 caaataaatc ttccgtggcg taagaaatag cgccgagaat ggtgagtaaa atattaaagg
     8281 ggttgcgata gcagacccat aaatgtaccc accacggcga cggttgttgt gcgggtaatt
     8341 tattttcacc atgttgttcg cgggcagatt ccacttccgc ctgatttaac ccttccggat
     8401 gggtgtcgaa cgttttccat aattcttctt cgggcatcac cgccattttc aggcaatgcg
     8461 cacttaagga cggcgggacc gccgtattca ctgtctgctg cgcgccaggc aatggatcgc
     8521 gatgaaccag acgggaaggt aaatggcgaa tgagccgggt aaaaatttct ttaaacataa
     8581 ggagtccctc cgcactgtct gaaacagtac agaaatgtct tcaggcgtgg cgaagcctta
     8641 cctgaaggta ataaagctga gcagggacgt taaaacgtca cggccttacg catccggtaa
     8701 cgccgtgaaa agacgggctt accggaaaag ttttaatctc cgtcgaggga gaggcgtggg
     8761 atcaggttcc atataacctc cggtaagtga aaaaagcgcc gcaaataata aggagaatcc
     8821 aataatattc gtagcatcta tggcgatata atacctgctg gcaactaaac caacgataaa
     8881 ccagacttta cccattgctg aatgcacggg taaagttagg ctcaaataat taaacaacac
     8941 gttacaggac aacaggatgc aaaatcggct gaccatcaaa gacatcgcac gcttaagcgg
     9001 cgtggggaaa tctacagttt cccgggtgct gaataacgaa agcggcgtga gccagcgcac
     9061 ccgcgagcgt gttgaagcag tgatgaatca gcatggattt tccccttccc gctctgcgcg
     9121 cgctatgcgt gggcaaagcg ataaagtggt cgccatcatt gttacccgtc tggattcgtt
     9181 gtcagaaaat ctcgccgttc aaaccatgct gccagcgttc tatgaacaag gttacgaccc
     9241 aatcatgatg gaaagtcagt tttccccaca attagttgcc gaacatttgg gggtgctgaa
     9301 acggcgtaat atcgacggcg tagtgctgtt cggttttact ggcataacag aagaaatgtt
     9361 agcccactgg cagtcatcgc tggttctgct ggcgcgtgac gcaaaaggct ttgcttcggt
     9421 ctgttatgac gacgaagggg caatcaagat cctgatgcaa cggctgtatg accaggggca
     9481 tcgtaatatc agttatctcg gcgtgccgca tagtgacgtg acaaccggta agcgacgtca
     9541 cgaagcctac ctggcgttct gcaaagcgca taaactgcat cccgttgccg ctctgccagg
     9601 gcttgctatg aagcaaggct atgagaacgt ggcaaaagtg attacgcctg aaactactgc
     9661 gttactgtgc gcaaccgaca cgctggcact tggcgcaagt aaatacctgc aagagcaacg
     9721 catcgacacc ttgcaactgg cgagcgtcgg taatacaccg ttaatgaaat tcctccatcc
     9781 ggagatcgtc accgtagatc ccggttacgc cgaagctgga cgccaggcgg cctgccaatt
     9841 gatcgcacag gtaaccgggc gcagcgaacc gcaacaaatc atcatccccg ccaccctgtc
     9901 ctgatcgttt cctgaacgat aaattgtgat cttcgctgcg tttcgggaac gttcccgttt
     9961 ttaaattttt ccgcgcaata tattctgcag ccaaccaaaa atgtcatctg ccatggggct
    10021 ttatgatgag caaaataaac caaacggata tcgatcggtt gattgaactg gtcggcgggc
    10081 gcggcaatat tgcgacagtg agccactgta ttactcgcct gcgctttgtc ctcaaccaac
    10141 cggccaatgc cagaccgaaa gaaattgagc aactccccat ggtgaaaggc tgtttcacca
    10201 atgccgggca atttcaggtg gtgattggca ccaatgtggg tgattactat caagcactaa
    10261 tagcgtcaac cggacaggcg caggttgata aagagcaggt aaaaaaagcc gcccggcaga
    10321 atatgaaatg gcatgagcag ttgatctctc atttcgcgga gatcttcttc ccgttgctgc
    10381 ccgcgttgat tagcggcggt ttgatcctcg gttttcgcaa tgtgatcggc gatttgccca
    10441 tgagcaacgg tcaaacgctg gcgcaaatgt acccttccct gcaaacgatc tacgattttc
    10501 tgtggttgat cggtgaagcg atcttcttct acctgccggt cgggatttgc tggtcagcgg
    10561 tgaaaaaaat gggcggtacg ccgatccttg gtatcgtgct tggcgtaacg ctggtttccc
    10621 cacagctgat gaacgcttat ctgctcgggc agcagctgcc ggaagtatgg gactttggca
    10681 tgttcagcat cgccaaagtg ggctatcagg cacaggtgat cccggcactg ttagccgggc
    10741 tggcactggg cgttattgaa actcgcctta aacgcatcgt gccagattac ctctatctgg
    10801 tggtggtgcc cgtctgttcg ctgatcctcg cggtgttcct cgcccatgcg ctgattggtc
    10861 catttggtcg catgattggt gatggcgttg cctttgcggt acgtcacctg atgaccggca
    10921 gctttgctcc gattggtgcg gcattgtttg gcttcctgta cgcgccgctg gtgatcaccg
    10981 gcgtacacca gaccaccctt gctattgatt tgcagatgat tcaaagcatg ggtggcacgc
    11041 cagtgtggcc gctgattgcg ctgtcgaata tcgctcaggg ctccgccgtg ataggcatta
    11101 tcatttccag ccgcaagcac aatgaacgcg agatctccgt gcctgccgct atctccgcct
    11161 ggcttggggt cactgagcct gcaatgtacg gcatcaacct gaaatatcgc ttcccgatgc
    11221 tgtgcgcgat gattggttct ggtctggcag gattgctatg cggcctgaac ggcgttatgg
    11281 cgaatggcat cggcgtaggc ggcctgccgg gaattctctc gattcaaccg agctactggc
    11341 aggtgtttgc gctggcaatg gctatcgcca tcatcatccc gattgtactc acctcgttta
    11401 tctatcagcg gaaataccgc ctgggcacgc tggacattgt ttaattttct tcggggcgca
    11461 attgcgccct ctcgcatttg caggaataac gtaatgacta atcttcccca ctggtggcaa
    11521 aacggcgtta tctaccagat ttatccaaag agttttcagg acaccacggg tagcggcacc
    11581 ggcgatttac gtggcgttat ccaacgcctg gactatctgc ataaactggg cgttgatgcc
    11641 atctggctaa ccccctttta tgtctctccc caggtcgata acggttacga cgtagcgaac
    11701 tatacggcga ttgatcccac ttacggcacg ctggacgatt ttgacgaact ggtgacgcag
    11761 gcaaaatcgc gcgggattcg tatcattctc gatatggtgt ttaaccatac ctctacccaa
    11821 catgcctggt ttcgcgaggc gctgaacaaa gaaagccctt accgccagtt ttatatctgg
    11881 cgcgatggcg aaccagaaac gccaccgaac aactggcgtt caaaatttgg cggtagtgcg
    11941 tggcgctggc atgcggaaag cgaacagtac tatttgcatc tctttgcacc agagcaggcg
    12001 gatctcaact gggagaatcc agcggtacgc gcagagctga aaaaagtctg tgagttctgg
    12061 gccgatcgtg gggtcgacgg gttgcgcctg gatgtggtga atctgatctc caaagaccca
    12121 cgtttccctg atgacctgga tggcgacggg cgtcgcttct acaccgacgg gccacgagca
    12181 cacgagtttt tgcacgagat gaaccgcgat gtgtttacgc cacgcgggtt aatgaccgta
    12241 ggtgaaatgt cctccaccag ccttgagcat tgccagcgat acgcggcact gacaggcagt
    12301 gaattgtcga tgacctttaa ttttcatcac ctgaaggtcg attatcccgg tggtgaaaaa
    12361 tggacgctgg ctaaacctga ctttgtggcg ttgaaaacct tgttccgcca ctggcaacaa
    12421 ggaatgcaca acgtagcatg gaatgccttg ttctggtgta accacgatca gccgcgcatt
    12481 gtttctcgct ttggtgatga aggtgaatac cgcgtgcctg cggcaaaaat gctggcgatg
    12541 gtgctgcatg gcatgcaggg aacgccgtat atctaccagg gcgaagagat tggcatgacc
    12601 aacccgcatt tcacgcgcat tactgactat cgcgacgtgg agagcctcaa tatgtttgcc
    12661 gagctgcgca acgatgggcg tgatgccgac gagttattgg caatcctcgc cagtaaatcc
    12721 cgtgacaaca gtcgcacgcc catgcaatgg agcaacggcg ataatgccgg gtttacggct
    12781 ggcgaaccgt ggattggcct gggcgataac tatcaacaaa tcaacgtaga agccgcgctg
    12841 accgatgagt cctcggtgtt ttacacctac caaaagttaa tcgcactgcg taagcaagaa
    12901 gccgttctga catggggcaa ttaccaggat ctgctgccaa acagccctgt attgtggtgc
    12961 tatcgccgtg aatggaaggg gcaaaccttg ctggtcattg ccaaccttag ccgtgggatc
    13021 caaccctggc agccagggca aatgcgcggc aactggcagc ttgtgatgca taactacgaa
    13081 gaagcctcac cacaaccctg tgccatgaat ttacggcctt ttgaggctgt ctggtggtta
    13141 cagaagtaaa tcttccctaa gccccggtaa tgccggtcat tccggggttt tgtctgtcag
    13201 catgttgttt ttgttgattt ttcaaccagc aaattcatta aaaaatttac ataacgctgt
    13261 agcgcccgtc atccgtacgc tctgcttttt actttgagct acatcaaaaa aagttcaaac
    13321 atccttgatg caaagcacta tatatagact ttaaaatgcg tcccaaccca atatgttgta
    13381 ttaatcgact ataattgcta ctacagctcc ccacgaaaaa ggtgcggcgt tgtggataag
    13441 cggatggcga ttgcggaaag caccggaaaa cgaaacgaaa aaaccggaaa acgcctttcc
    13501 caatttctgt ggataacctg ttcttaaaaa tatggagcga tcatgacacc gcatgtgatg
    13561 aaacgagacg gctgcaaagt gccgtttaaa tcagagcgca tcaaagaagc gattctgcgt
    13621 gcagctaaag cagcggaagt cgatgatgcc gattattgcg ccactgttgc tgcggttgtc
    13681 agcgagcaga tgcagggccg caaccaggtg gatatcaacg agatccagac cgcagttgaa
    13741 aaccagctga tgtcgggtcc atacaaacaa ctggctcgtg cttacatcga gtaccgtcac
    13801 gatcgcgaca ttgaacgtga aaaacgcggt cgcctgaacc aggagatccg tggtctggtc
    13861 gagcagacca acgcctcgtt actcaacgaa aacgccaaca aagacagcaa ggtgattcca
    13921 acccagcgcg acctgctggc cgggatcgtg gctaaacact atgcacgcca gcacctgctg
    13981 ccgcgtgacg tggtgcaggc acatgagcgt ggcgatattc actatcacga tctcgattac
    14041 tcgccgttct tcccgatgtt caactgcatg ttgattgacc tgaaaggcat gctgacccag
    14101 ggctttaaaa tggggaacgc cgagattgaa ccgccgaagt cgatctctac ggcaaccgcg
    14161 gtaactgcgc agattattgc tcaggtcgcc agccatattt atggcggcac caccattaac
    14221 cgtatcgatg aagtgctggc accgtttgtc accgccagct acaacaaaca tcgcaagacc
    14281 gcagaagagt ggaacatccc ggacgccgaa ggctacgcta actctcgtac catcaaagag
    14341 tgctacgatg ccttccagtc gctggagtac gaagtaaaca ccctgcacac cgccaacggt
    14401 cagacgccgt ttgtaacctt tggttttggt ctgggcacca gctgggagtc gcgcctgatt
    14461 caggaatcta tcctgcgtaa ccgtatcgca ggcctcggta aaaaccgtaa aactgcggtg
    14521 ttcccgaaac tggtgtttgc gattcgcgat ggtctgaacc ataaaaaagg cgatccgaac
    14581 tacgacatca aacagctggc gctggagtgc gcaagcaagc gcatgtatcc ggatatcctg
    14641 aactacgatc aggtagtgaa agtcaccggt tcgtttaaaa ccccgatggg ctgccgcagc
    14701 ttcctcggcg tgtgggaaaa tgaaaacggc gagcagatcc acgatggtcg taacaacctt
    14761 ggcgtgatca gcctgaacct gccgcgtatt gctctggaag caaaaggcga tgaagccacc
    14821 ttctggaagc tgctggatga acgtctggtg ctggcacgta aggcgctgat gacccgtatc
    14881 gctcgtctcg aaggcgtgaa agcgcgcgtg gccccgatcc tctatatgga aggtgcttgt
    14941 ggcgtgcgtc tgaatgctga cgatgatgtt tctgaaatct tcaaaaacgg tcgtgcgtct
    15001 atttcgctgg gttacatcgg catccacgaa accattaacg cgctgttcgg cggcgagcat
    15061 gtttacgaca acgagcagct tcgcgcgaaa ggtatcgcca ttgttgaacg tctgcgtcag
    15121 gcagtggatc agtggaaaga agaaacgggt tacggtttca gtctctacag cacgccgagt
    15181 gaaaacctgt gcgaccgctt ctgccgtctc gatactgctg agtttggcgt ggtgccgggc
    15241 gtaacggaca aaggttacta caccaacagt ttccacctcg atgtggagaa gaaggtgaac
    15301 ccgtacgaca agatcgactt tgaagcgcct tacccgccgc tggcgaacgg tggtttcatt
    15361 tgctacggcg agtatccaaa cattcagcac aacctgaaag cgctggaaga tgtctgggat
    15421 tacagctatc agcatgtacc gtattacggc accaatacac cgattgatga gtgctacgag
    15481 tgtggcttta ccggtgagtt cgagtgcacc agcaaaggct tcacttgccc gaaatgtggt
    15541 aaccatgacg cctcccgtgt gtcggtaact cgccgcgtgt gcggatattt aggtagcccg
    15601 gatgcacgtc cgtttaacgc tggtaagcag gaagaagtta agcgccgcgt taaacatttg
    15661 gggaatgggc agataggtta atcttcactc tacgttaagc aaatgccgga tgcggcgtaa
    15721 acgccttatc cggcctacat ggcaacaacg attgtaggtc tgataagacg cgacagcgtc
    15781 gcatcaggcg ttgattaccg gatgcatcct atacgcggac tgataagcca ggcgaaacaa
    15841 tgaattatca tcagtactat cctgtcgaca tcgtcaacgg ccccggcact cgctgcaccc
    15901 tgtttgtctc cgggtgtgtt catgaatgcc ccggttgcta taacaaaagc acatggcggg
    15961 taaattccgg tcagacattt actaaagcaa tggaagacca gatcattaac gatctgaatg
    16021 acactcgcat caaacgccag ggtatttccc tctccggcgg cgatccgctg catccgcaaa
    16081 acgtgccgga tattctgaaa ctggtacaac gcatccgcgc cgagtgtccg ggtaaagaca
    16141 tctgggtgtg gacaggctat aaactcgacg aactcaacgc tgcgcaaatg caggttgttg
    16201 atttgattaa cgtgctggtc gacggcaaat ttgtgcagga tttaaaagac ccttccctga
    16261 tctggcgcgg cagcagcaat caggtggtgc atcatttgcg atgataagtt ccctgttacc
    16321 tgagtgcagg caacagggaa atgaggaatt aacgatactt ctggtgatag gcgttgcggg
    16381 tcgttttcag ttgctctgcg gcagcctgcg cttcttttac tttaccttca tttgccagct
    16441 tcagcgcgtc gtcaatctga ccgaccagaa tgtcgaaacc gtggcggaaa tctttcattt
    16501 ccgggctgtc cggtgattta tcttcgagct tcggcggcgt tgctttttgc gcatccagcg
    16561 ccgcggcacg cattttggtt aacgcgtctt tgacttgcgt cgcgttatcg gctttttcga
    16621 ccacttttaa attgtcgttg agggtttcca tattgtcttc aagatcagcg gcaaacgacg
    16681 ccgaactgaa taccaacgag gagactgcaa gaatagctaa caggctttta cgcattgctc
    16741 acttcctttt ttattatgaa gatttggcgc ggcaggtcgc gccagttttt tactgcccgg
    16801 cgattttcat ctccgacaac agcacagaac cacactgtat attactgcgt gtttcaatat
    16861 cgttaccgac ggtgacaata ttgcgccaca tatcttttaa attacctgcg atggtgattt
    16921 cgctcaccgg atactgaatt tcgccattct ctacccagaa gcccgccgca ccacgggaat
    16981 aatcaccggt aattgcactc acgccctggc ccatcaattc cgtcaccacc agcccggtgc
    17041 ccatctcttt gagcatctgc tcgaagctta gaccttgtcc ggcaatccgc cagttgtgaa
    17101 taccgcccgc atgtccggtg cttttcagcc ccagttttcg cgccgagtag ctggtcagca
    17161 gccactgagt caggatgcca tctctaataa tatcgcgacg ctcggtgcgc acaccttcgc
    17221 tgtcaaatgg cgtcgatgcc agccctttca gcagatgcgg atgctcttca atggtcagcc
    17281 agtccggcag aatttgttta cccagcgaat ccagcaggaa ggtagattta cggtaaaccg
    17341 ctccacccgc tatcgccccc accagatgcc caaaaagccc ggttgccact tcattggcaa
    17401 aaatgaccgg cgctttcatg gtggagagtt tacgcggtga caggcgcgat aaagtacggc
    17461 gagcacagtc ggccccaacc cactctggcg tttgcagatc gctcatcgca cgaccaatgg
    17521 tgtaggcgta atcacgctcc atatcgccat tttcttcggc aattacacag ctggagagcg
    17581 aatgacgcgt agagcagtaa ccctgcaaca tgccgtggct gttgccaaaa actttgacac
    17641 cgtagtggct gttaaagctg ccaccttcgg tattggtgat acgtttgtcc gcctgtaatg
    17701 ctgcctgttc tgcgcgggcc gccagttcaa tggcttcatc cggggaaact tccgcagggt
    17761 ggaacaaatc gagatccggt gcctcaaagg ccagcagctc tttgtctgcc acgccggcac
    17821 agggatctgg cgaggtataa cgggcaatat ccagcgccgc ctgtacggtg cgggcaatgg
    17881 cctgcgggct taaatcggtg gatgatgcgc tacctttgcg gttctggtga taaacagtga
    17941 tccccagcgc gccatcgcta ttgaattcaa cattctccac ttcaccataa cgcgtgctta
    18001 cgctaatgcc ggtggtcttg ctgacggcaa cttccgcacc gtccgatttg cctgaggcca
    18061 actccagcgc agtggaaact gcttcttcca gaatcttgcg ctgcgcttca acttgagaga
    18121 ttactttcat tgcaagtgcc ataatgtaga gagtttctct gaagtctaac agagaaccgt
    18181 ttttcagtgc gcatcttaac tggtaacatt agcctctttt tttaaggagc ctgagatgac
    18241 taagcagccc gaagactggc tcgacgacgt tcccggtgat gacatcgaag acgaagacga
    18301 tgaaattatc tgggtcagta aaagtgaaat taaacgtgat gccgaggagc taaaacgcct
    18361 tggcgcggaa attgttgatc tggggaaaaa cgcgctggat aagatcccgt tagatgcgga
    18421 tctgcgcgcg gctattgagc tcgcccagcg tattaagatg gaaggtcgcc gccgccagtt
    18481 gcagctcatc ggtaagatgc tgcgccagcg cgatgttgaa ccgatccgtc aggcgctgga
    18541 taagctgaaa aaccgtcaca accagcaggt ggtgctgttc cataaactgg aaaatctgcg
    18601 cgatcgtctg atcgaccagg gtgatgacgc catcgctgag gtattaaatc tgtggcccga
    18661 tgccgatcgt cagcaactgc gtactctgat ccgtaacgcg aagaaagaga aagaagggaa
    18721 taagccgccg aaatccgcac gccagatttt ccagtatctg cgcgaactgg cggagaatga
    18781 agggtaattt tcgttgttga tgtgagtatg gtttgccgga tgcggtgcac ctgtaggcct
    18841 gataagacgc atcaagcgtc gcatcaggca ctatgctcaa atgccggatg cggcgtgaac
    18901 gccttatccg gcctacgcac actatatcag gctgaggccg aattactgcg cagcttccgc
    18961 cttcttcgcc agaccatcca gcagtttctg atggatccca ccaaaaccgc cgttgctcat
    19021 caccagaata tggtcgccag gctgagcggt tttcaccacc atatctgcca gcgtatccac
    19081 atcgccactc cagtgtgcag gctgaacgca ggcttctgcc acttctgcca cctgccacgg
    19141 aatatgcgcc ggttgcagca ggaagacttc atcggcacga cctaatgaag gtgccaaatc
    19201 gtctttgcag atccccattt tcatggtatt cgagcgcggt tccagcacag caataatgcg
    19261 cgccgtacca ccaactttgc cacgcagcgc cgccagcgtt gccagaatcg ccgtcgggtg
    19321 atgggcaaaa tcgtcatata ccgtgacgcc attcgcttca ccacgcaact ccagacggcg
    19381 acgagcatta ataaacgaac ccagcgcgtt agcggcatct gccggcgcta caccaacatg
    19441 gcgagccgct gcaatcgcca tcaggccatt gtgcatatta tgttcgccta ccagcgacca
    19501 tttcacttcg cccacttttt cgccatccag caaaacttcc cattcggaag catcggtggt
    19561 cagctttttc gcctgccagt gaccctgctc acccaccagc tcctgctcgc tccagcagcc
    19621 catcgccatg gtctgtttca ggttgatgtc attttccggc cagataatac ggccctgccc
    19681 cggaacgata cgcaccagat ggtggaactg tttctggatc gctttcaggt cgtcaaagat
    19741 atcggcgtga tcgaactcaa ggttgttgag gatcagcgta cgcgggcagt aatggacaaa
    19801 tttagagcgt ttgtcgaaga aggcgcagtc gtactcatcc gcttcgataa caaagaagtc
    19861 gctttcgccc agacgcgccg aaacctcaaa gttccccggc acaccgccga tcacaaatcc
    19921 cggtttgtaa ccgcactgtt ccagaatcca ggtcgccatt cccgcggtgg tagttttgcc
    19981 gtgtgtaccg gcaacggcca gcacccagcg gtcacgcagc acaaaatcgt gcagccactg
    20041 tggacctgac atataaggga tgtttttttc cagtaccgct tccacacacg gatttccacg
    20101 ggtcatggcg ttgccaataa tcaccagatc cggctgcgga tcgagctggc tggcatcgta
    20161 accctgaatc agttcaatgc cttgcttctc aagtaaggtg ctcatcggcg gatacacatt
    20221 ggcgtccgaa cccgttactt catggcctaa ctggcgcgcc agcatcgcca gaccgcccat
    20281 aaacgtgcca caaattccta aaatatgaat gcgcatacgt cactatcctt ttttaatctg
    20341 ccgctcattt tacgcatatg tcgggcaagt gagaaacgca tttcaggata atccgcaatt
    20401 tgctggcgcg attcacctga gcgcaacatt gagattattt gttaagattg ttgcggtcgc
    20461 tttactccat aaacattgca gggaaagttt tatgaaaacg ttaggtgaat ttattgtcga
    20521 aaagcagcac gagttttctc atgctaccgg tgagctcact gctttgctgt cggcaataaa
    20581 actgggcgcc aagattatcc atcgcgatat caacaaagca ggactggttg atatcctggg
    20641 tgccagcggt gctgagaacg tgcagggcga ggttcagcag aaactcgact tgttcgctaa
    20701 tgaaaaactg aaagccgcac tgaaagcacg cgatatcgtt gcgggcattg cctctgaaga
    20761 agaagatgag attgtcgtct ttgaaggctg tgaacacgca aaatacgtgg tgctgatgga
    20821 cccactggat ggctcgtcca acatcgatgt taacgtctct gtcggtacca ttttctccat
    20881 ctaccgccgc gttacgcctg ttggcacgcc ggtaacggaa gaagatttcc tccagcctgg
    20941 taacaaacag gttgcggcag gttacgtggt atacggctcc tctaccatgc tggtttacac
    21001 caccggatgc ggtgttcacg cctttactta cgatccttcg ctgggcgttt tctgtctgtg
    21061 ccaggaacgg atgcgcttcc cggagaaagg caaaacctac tccatcaacg aaggaaacta
    21121 cattaagttt ccgaacgggg tgaagaagta cattaaattc tgccaggaag aagataagtc
    21181 caccaaccgc ccttatacct cacgttatat cggttcactg gtcgcggatt tccaccgtaa
    21241 cctgctgaaa ggcggtattt atctctaccc aagcaccgcc agccacccgg acggcaaact
    21301 gcgtttgctg tatgagtgca acccgatggc attcctggcg gaacaagcgg gcggtaaagc
    21361 gagcgatggc aaagagcgta ttctggatat catcccggaa actctgcacc agcgccgttc
    21421 gttctttgtc ggcaacgacc atatggttga agatgtcgaa cgccttatcc gtgagttccc
    21481 ggacgcgtaa tctcctgcgc ctctccacac ggagaggcgt ttttatcgct gcgcaatgtt
    21541 gactcttgtc acaggcgaac tctgacgatt ctcccacagc accgttaatc cacgctgtaa
    21601 tgctataaaa ataaataaca aaataccgat ggcgattttc gtccaccatg agctcagcgt
    21661 gccatcaaag ttgatataag tctgtattag cccctgaatc gccacgccaa aaagcgtccc
    21721 taataccgtt ccaacgccac cgctcagaag cgtaccgcca attaccactg aggcgatagc
    21781 atccagttcc acacctacgc ccgccagcgc atatccggcc tgggtataaa tcgagaagac
    21841 aatccccgcc agcgttgcca gtccggtgga gagcatataa atgcgaatag tggtgctgcg
    21901 agtggaaatc cccatcaggt tcgccgacgt tgcgttgccg ccaatggcgt atacctgatt
    21961 accaaaacgg gtacgatgcg cgaggaaaat accgataacc accaccgcca acatcagcag
    22021 tcccatcgca cttaagcgac cgccgccagg gattttccac gcaaggcttg agagcgtgtc
    22081 ataaatggga tggtttatcg gaatcgactc ttccgaaacg agatagctga caccgcgcaa
    22141 aaagaacatc cccgccaggg taatgataaa tgccgggatc ttcagggcgt cgatcaaaag
    22201 ccccataaat gcgccgaagg cacagcccat caccagcact agcggaaacg ccagtagcgg
    22261 cgagaggccg aaatcgccaa tcacttttgc cagaaacacg ccagtaaagg cgatcaccga
    22321 accgacggag agatcgatcc caccggagag gatcacaaag gtcatgccaa cggcaatgat
    22381 cccaagaaag gcgttatcgg tcaggatatt gcagatcact cttgtggaag caaaaccggg
    22441 aaactgggtc aggcagtaaa gataacccaa cacaaagacg ccgatggtga tcatcagtgg
    22501 caaattacgt tttatcacgg ctacgtactc ctttaatcag actgataaag cgttgcgact
    22561 ggacaatcag cacgcaaaga accaccaccg cttttacaac ctggttcatc tctggcggaa
    22621 agcccgaaag caaaattccg gtgttcatcc cctgaataat cagcgccccc accaccgaaa
    22681 gcagtaggtt aaaacgtccg cccatcagcg atccgccgcc aataaccacc gcgagaatgg
    22741 cgtccagctc cagccataac ccggcgttat tggcatcggc accgcgaata tccgccgcca
    22801 cgataatgcc cgcaatcgcc gcacacagcc cgctcaacac gtaggtaagc atgacgatga
    22861 tccgcgtgtt taccccggca ttttttgccg cccgaatgtt gataccaacg gcttcgataa
    22921 acatccccag cgccgttttg cgggtcaaca gccagaacag gataagcgtc agcaccgcga
    22981 taatgaccgg cgttggcagg aacaacagcg atccactgcc aaaccatgag agatccggcg
    23041 agttaaacgt gacgatctgt ccggaggtga tcagttgcgc cacgccgcgc ccggcgacca
    23101 tcaggatcag ggtggcaaca aacggctgaa ttttgaggat cgctaccagt atgccgttcc
    23161 acaatcccgc caggatgcca gtgcccaggg cgcttaacaa aacaatcggc aggctgaatc
    23221 ccgcgaccgt catcgcagcc gttgtggctc cggcgatagc catcaccgcc cccacggaga
    23281 gatcaatccc acctgttgcg atcaccagcg tcattccgat agccaacagc gcaacggggg
    23341 ccgcacggtt aagaatgtct atggggctac cgaataaacg cccatcctgg agcaccacct
    23401 gccagaaatg cggggccacc aggctatcga ccagcagcac cagcaacagt gccgccagct
    23461 gcggcattcc cgttggccag cgaaagcgcc ttttcggcgg cgtagtgtcc gggagagatt
    23521 gaggcatcac actgttctcc ttacgccgca atggcgttca tgatcgccgg aacggaaagc
    23581 tctgccagcg ggatctccgc cacctgtttg cgatcgcgca tgatgatcac ccggtcggca
    23641 tagcccacca gttcttccag ttcggaggag atcaccagca gcgccagacc atcggcgcat
    23701 agcgtttcaa tcaggcggat gatctcggcg tgggcaccaa catcaatgcc gcgagttggc
    23761 tcatcaagga tcagaaattg cggtcgggtc agtagccaac gtgaaagcaa cactttttgc
    23821 tgattgccgc cagagagaaa ttcaatcggt tgttcagttg aaggtgtgcg aatgccaagc
    23881 tggcggataa agcgttcggc aatctcttgc tgttctttgc gggaaatggg acgtagccag
    23941 ccgcgctggg cctggagagc gaggatgata ttttcccgca ccgaggcggc agcgatgatg
    24001 ccatcggttt tcctgtcttc cgggcagaag ccaatgccca gtaccgaagc ctgatgtggc
    24061 gatcgcaggt tttgcggttt gcctttgatc aacgccgtgc cgctgtcagc aggtttgata
    24121 ccgaagatca cttcggcggt ttcggtacgt cctgatccca gcaatccagc cagaccgacg
    24181 atctcgccgg ggcgtacttc gagatcaaac ggtgcgatcg ttcctttttt gccgtaattt
    24241 ttgaacgcgg caacgggttt gtcgctcaac aatgttcgcc cggcacgctg tagcgcgtgg
    24301 gtatccagct cgcgccccag catcattttt accagttcga tctgcggtag ctcgcacgtt
    24361 tcccgacagc ctacgaaact gccgttgcgt aagacggtga tccgatcgct gacctgatag
    24421 acctgatcga gaaagtgagt gacaaaaatc aggctgacgc cgcgatcgcg caactgacgc
    24481 atcaggtcaa acagtaactc cacttcctgg gtgtcgagac tggcggtggg ttcatcgagg
    24541 atcagcactt tggcagagag atcgatagcc cggcaaatag cgacgatttg ctgcatcgcg
    24601 actgaaaagc ggttgagcgg ttcgcgcacg tcgagggaga aaccgtaaga tgccatcagt
    24661 tcggtggcgc gcttttccat ctctttgcgg cgtagaaggc cgaagcgttt gggttcgcgg
    24721 cctataaata gattatcagc gaccgacata ttgggtagca ggtttacttc ctgatagacg
    24781 gtgccgatac cgagttgttg tgcatgggcg gtatttttcg gtgagatagc ctggccttcc
    24841 agccagatgg tgccgcgatc ggcgtggtat acaccagtta atgctttgat tagcgttgat
    24901 tttcctgccc cgttttcacc gagcagcgcc atgatttcgc cgcggcgcag gctgaaatca
    24961 acgttgtcta acgctttgac gccggggaaa aatttactta atccttcggt gcggaggatc
    25021 tcctggtgtt ggttagtcgt catggtttcc cccggtgtaa agcgtgctcc cagtaggcat
    25081 gataagacgc ggtaagcgtc gcatcaggct tcagcgcacc accgccggat gcggcgcgag
    25141 cgccttatcc ggcctacgaa tcggcatcag gcatagcaac cctcaatacc ccatattttt
    25201 cttcttctct aactcttctt ttgcggtatc aggcagataa agggtggatt tggtcagcgt
    25261 cagcttttca ggcatggtgc cgtctttttt gtatttctcc agcgcgtcga aggcgggacc
    25321 tgccatattc ggcgtcagtt caacactggc gttcgcttcg ccatcaatca tcgctttgta
    25381 gatatccggt acgccgtcga tagaacctgt cagaatatct ttgcctggtt tcaggcccgc
    25441 ttctttaatt gcctgaattg caccaatcac catgtcgtcg ttatgggcgt aaaccatgca
    25501 gatgtttttg ccgttgtttt ccgctttgat aaagctctcc atgacttctt tgcctttact
    25561 gcgggtgaag tcacctgact gcgagcggat aattttgata tttggcgcat tcttaatggc
    25621 ttcggcaaag cctttcttac ggtcaatggc gacgctggcc ccaacagtgc cctgcagctc
    25681 caccacgttg catggtttgc cattcacttc ttttaccagc cagtcaccaa tcaacttgcc
    25741 ttcgagaatg ttgtcggcag tgacggtggt catatagaga gatttgtctt tcacatcaat
    25801 agaacgatcg agcaagaaga ccgggatttc ggcatctttc gcctctttta ataccggttc
    25861 ccaaccagtc gcaaccaccg gagcgataaa gatcgcatcc accccttgcg cgacgaagga
    25921 acgtaccgct ttaatctggt tttcctgctt ttgctgacca tcggcaattt tcagcgtaat
    25981 tccgcgtttt tcggcctcac ttttcgccac attggtttct gcggcgcgcc agccagattc
    26041 cgatccgacc tgcgaaaatc ctacggttaa tggagcggcc aacgccatag acgacatggc
    26101 tgccgagact gcagagacta caagtaagcg tttccacata gggttgtcct cgtcggggta
    26161 attattattg gtgaaaagat gttcgcgaaa aaactataga caattcgtta tgtaacggat
    26221 tgcgttacat cacacttcaa agaagtaaat aaaacgttaa tcacaagttt gtaatcgctt
    26281 tcatctcact atgaaaaatg cggctacggt tatggatttt cctgctctgt ataccgtctt
    26341 aaaattggcg aaaaaggaaa atgaagacga aaacaagcga agacattcgg cgcgagttgg
    26401 ctataatact cggcacttgt ttgccacata tttttaaagg aaacagacat gagcttactc
    26461 aacgtccctg cgggtaaaga tctgccggaa gacatctacg ttgttattga gatcccggct
    26521 aacgcagatc cgatcaaata cgaaatcgac aaagagagcg gcgcactgtt cgttgaccgc
    26581 ttcatgtcca ccgcgatgtt ctatccgtgc aactacggtt acatcaacca caccctgtct
    26641 ctggacggtg acccggttga cgtactggtc ccgactccgt acccgctgca gccgggttct
    26701 gtgatccgtt gccgtccggt tggcgttctg aaaatgaccg acgaagccgg tgaagatgcg
    26761 aaactgattg ctgttccgca cacaaagctg agcaaagaat acgatcacat taaagacgtt
    26821 aacgatctgc cagagctgct gaaagcgcag atcgctcact tcttcgagca ctacaaagac
    26881 ctcgaaaaag gcaagtgggt gaaagttgaa ggttgggaaa acgcagaagc cgctaaagct
    26941 gaaatcgttg cttccttcga gcgcgcaaag aataaataag ttcttctagc gcaataaccc
    27001 tgaacgccgg gcttcggtta gtaagggttt ttttatgccc gcgataaata aactctctat
    27061 tccaccatca ttattctcag cggttgcaag gcttgaacgg taagaacaag caaacccgac
    27121 caccattttg ctgttcatag ccacttgctg gaagttagcc gacctcactc atactcaccg
    27181 ttcaaagcgt gcccccgttt tacccctgca catttgtgaa cgccagcaga gttttttatg
    27241 cgattgcaga tatggaaagc ggctcggaga gaaaagcaaa agatggaaaa gttacaaaaa
    27301 aaaatcgcga gatacatcgc ataaaacaac gccacccgaa ggtggcgtgc ttttattatt
    27361 acttatccct gtctaaccag tcgccgcttt caattagctt taatccatcg acgggtcgtt
    27421 gataaacgta catccatgca ctcccgtacg gcgtctgaat caactggcgc gcgtattcac
    27481 cgcccctggt gcgcaaggca tcaagttcgg ccagcgtggc gttgtcaata cgataaactt
    27541 caccgtgtac tgttccgttc cccggaactg cgcctggata gtggcccagg ctatacaact
    27601 ggtagttatc gatactgaaa tcgcccagta actgggcatt ggtcatccag tgactgttgc
    27661 cttgtttgtg gcgtaaactg ccgtagacaa atattcgcat tgctaaaact cgaactgata
    27721 gagcaaatcc agtgcctggt ctacaccaga cacggcttcc agatatagct taggcatcag
    27781 gcgataacgt aacgtgagtg ttgctataga gtcaaatata cccacgccgt atttcacttg
    27841 cagacctggc aatacatagc cgctgaccac tacctgggag gagtcgccta ctccctgggt
    27901 gtcgagcgct aaattgctta cgccaaacgt ctcgccgatt ttacccacaa tctggccact
    27961 ttgcgcaacc cccagaccaa tcagcatcga ggtcattgcc gcactgtcgc tctgatcgct
    28021 ctccagccct tgtccacgta gcaaataaga caatgcagct tgttgcgaca tcgccgggtc
    28081 agagaagatc tccgctttcg gttcgtccgc cagaccagtg acgcgaactc cggcgattac
    28141 gtcgtcttct gtagcatccg ggttacgaat agcttcaata ttaagatacg gttgatccgg
    28201 cggaccagag aacagtaact cacctttacg cacaatcaga tcctgaccat aggcatggaa
    28261 gcgcccttca gggatgttga tctgcccgtt caggcccagc ccttgtttgt cctgaacgac
    28321 gttaagatcg cccgtcagcc gcgctttcag gccaaaggcg tcaatgcgca cattgttgcc
    28381 aacgtggaca atcaggttac tgttaatcgg aatcgacgcc gttttcggct cttccggttg
    28441 caggttatcg ttaagcatca ccacatcgct ggagacgcct actgcgcttt ccggcagatc
    28501 gtgcaccacg atgcgcgccc acgggacatc cacgcgacca tcgagggtaa acaggtttgg
    28561 tgtagcctcg aagacaacat ctggcgatac atccattcgt accatcggcg gcacggtgat
    28621 ccgcacttta ctgcctttcg ccgttacccg cgcccgccag ttttcaattt ggctccagtc
    28681 ggcatcaccg ttcaggtaga tttcaccctg ctgggtccgt actgtaccgg caagcgtcga
    28741 gcgcatacca ttaaagttga ccgcaagctg gctcggttgc atatcaaacg gcataaagtt
    28801 gccgtcgata tccacacccg taacctgaag ctgaccaaac aactgcgggc tttgcacatc
    28861 accacccaga cgcaagttgg cactcaccat ccccgctgct ttttccccac gggtaaagat
    28921 ggggtttatc atcgcaaggt tgaagttacg gatattgacg ttgccaccaa gattacggcg
    28981 gccttgcgga tcggtcacct gcacctgtcc atcaaactgg ccgttattgg tcaggcggat
    29041 ggtccagccc aattcggcac ggttgttacg caattccgcc gtcagattca gtgtctgaaa
    29101 cgccacgggc agcgccgcat cgttgacggt ttgcgttacc tgcacgttac gccccgaaag
    29161 ggtgatactg ccctgcggca gcccctcttt ggtggtgtcc caggcaacgt ccgctttacc
    29221 cgtgaagata ccgctggcct gagtggtttc tggcataaat ggtttcagca tggccaggtc
    29281 gaagcggttg agattcacca ccgcacgccc ttcggcaccc gcatcgatag tttgcggcac
    29341 gcacagttcc gcattcgggt taagccagca gtgtggcccg atgctgattt tttgctcctt
    29401 attgcggtaa tccagcgcaa tatcgcgggt cagcgaccac gggccgaccg gcgtctggaa
    29461 gcgggtattg ctaagagttc ccttccagcg ttcttctttg cgatcaaaac ttcctgccag
    29521 attaagctgc ccggagacag gctcgccctg aatccgcaac tgtaactcgt gctgtttttc
    29581 gctgcctttg gcattcaggg tgacgaggtt gatatttaca tccggctgcg aaatttgctc
    29641 aacgcgtacg tcgagtttcc cggcgatctg atcggtggat ttaatgtcgc cttccacgcg
    29701 aacctgcgcc acggaaagtt cctgccagcg caggccgcgc gcggtgatat ctgccagtag
    29761 ttgtggcgct tccaccgtgc cgcgtacttt caccagccct ttcgctgtac cgccaagccc
    29821 cggcagcgcg ttatccagcc ccggcgcgtt gatggtggca tcaagattga gatcttttac
    29881 ccccagctcg cctttcactt cggcactgtt tggccccagt tccagatgaa gccctgggat
    29941 catccactgc atataactgt tgcctttcag cgtgccgtca acgttcactt tgttctgttt
    30001 gacgttaccg gtcagcttca gttctggcac ctccatctgc caggtgccgc cgtacaggct
    30061 accgcgggtt ttaatcaagc cattgagttt cgacggccac tctgggatct ctttggcggt
    30121 gttaatgccg ttaagcgtta gctcaccgcg ccaactaatg gcctgctgcc agtcgagcaa
    30181 cgccttgagt tcagttttcc cttccagcgc cgcgacggtg agtttgtcga gattgacctg
    30241 ctgttcatta cctttggcat caagggtaat ggtggctggc gggatctcca gtcccttcac
    30301 tgccgtacgc atagagagcg tgtaatcggt cattttgccg gtaagtttca gtttcagatc
    30361 atccgcctga tactgcttct caccagtgaa cggccagtaa atctgtttgc tgttcacttc
    30421 cacgttgagc ggcaatccgg cttccgccag tcgcgtctgg gcgcgtaaat ccatatccac
    30481 cggaccggaa agattaacgc caatctccag ctgttcgcgc agcgcgccgc ccactttcag
    30541 cttcaccttt tcacctttca acggctccac gttcagtgta ctattgagag tgatgtccac
    30601 cggccagttg tctgacagct gcgccgtgcc gctggcgttg acgatccctt gactggaatc
    30661 gatatccagg gcgtccagtt tagtattgcc gtcaatgctg ctcactttca gcagcatggt
    30721 gcgcacggtg atgtccgtgt cgcccgtcac gcgtaactgc tcgcctttaa actcttcaat
    30781 gttcaggtta agcggcaaat gcacgtcggt catttccggc aataccgggc gagaaaagag
    30841 atctttcagc gtttcgccga gcggcttttc ctccggctgc ggattttcaa ttttcggttc
    30901 gaccacttct tcctgcgcca cttccgccac tttcggcaga gcaatcagca ggcctttcag
    30961 cgacgtcggt ttcagggtca gggttttctc ctgccagttc aggccggagg tgaagtccat
    31021 caccgatacc gtggtgtcat caatcttgat gttgacgttg tccagtgcca cccgtgttag
    31081 ggtgatggga tacggcgtgg agagatccag cggaccgcta tcttcctctt cttcaacctg
    31141 ttcagaaggg ggcatttttt tgctgtcgat attgacctgg atgtctttca gcgccagatc
    31201 attaatacaa acactgctgt tccacaggca ctcaagcccg accgccagat gcagattgcc
    31261 tgcttttacc gccacgcctg gctgctcata acgaacgtca gacaaggtga gatcgcgcca
    31321 gccgccggtg accttgccaa catccagtcc tggcacccag cgatccgccg ctttaaatac
    31381 cagatgcagg ccgctggtgg tgcccaccag aaacgccacc gatcccagca acagtaagat
    31441 aacgataacc acgccgaggc tgattttttt ccataaactc ataattctgg ccccagaccg
    31501 atgtaaaact gtaacccgtg ttcgtcttta tccgcgaccg gtacggcaaa atcgagtttg
    31561 attggcccga ccggcgattc ccagcgtacg ccgaccccgg taccggtttt aaagtcgctg
    31621 cggcgaatat cgcttaccgc ttcgccacta tcgacaaaca ccgcgcccca ccattttccg
    31681 gtcacgttgt actggtactc cagcgatccg gttatcaact tcgaggcccc tttcaggtca
    31741 ccgttggcgt atttcggagc gatagatttg tatttgtagc cacgaatact gcggtcgccc
    31801 ccggcgaaaa aacgcagatc cggcggtact ttgtcgaaat caccggtttc aatccagccc
    31861 agcgtgccgc gtgtcacaaa acgatggcga tcgtacagtg tgcggatcca gacgttttgt
    31921 gcctggaaaa cggagaaatc gacatctgag ccccaggcag tgttggagta gtcgatagag
    31981 tagcgttgcg agtcgcccca ggttggcatc aggccaccac gagaacgcgt gcggctaatc
    32041 atcaccccag gataaaacag catcgtggtg ttggtaattt caccctgggt aaagtggtcg
    32101 agactccagc gcaggttaat ggcacgctgc cagccgctgg agagatccca gtagcgagaa
    32161 gccaccagcg tagtggagtc agattcggta tcgttcaggt cagtgcgctt aaaaccgccc
    32221 tgcaccaaat aatattgttc cagtggattc ttcagcagcg gcattttata gctgaagtcg
    32281 aggatctgtt ccggcgcgga aatactggta ctggtggtca gactgtgacc gtatgagttc
    32341 atccacggtt ttttccacgt cgctttcacg cgcggtccca cgtccgtaga gtaaccgacc
    32401 ccggtttcga tggtgttttc tgttcgcggc gaaaccacgc ccgtcaatgg taatactttc
    32461 gtttcgcgcg ctttatcaaa ttgtggagcc accaccaccg agttaaacca gccggtagca
    32521 gaaagtcggc ggttcagttc cgccagatct ttcgattcgt actcatcgcc ctctttaaac
    32581 ggcaccagat tttgcaggta ttcatcgcgg atttgtgatc cttcaaaggt cacatgccca
    32641 aagcggtaac gttcgccact gttataatca atatcccaga aggctttatg caggccgagc
    32701 gcaatgccca gctgcgcttt ggtaaattcg ctatcgaaat aacctttacg caacgcaatg
    32761 ctggttaagg actttttgaa attttcataa tcgccctggt tcagcactgt gccaatagcc
    32821 gggcgagtat cgagcaattt caaatagtct ttatcggtcc gcgcgccgcc gcgcaatacc
    32881 acatcggtgc cgccaattaa caccggcacg cctggcgtga ctttggcgat caatacctgc
    32941 cgccctttct ttggcggtgg acggagatca aattcaatgg tcggctggta ataacccagc
    33001 gctttcagac cttcgcggat ggcatcatcg acgcgtgcgc gaaagcgacg gtctggcgtc
    33061 acttcatcac tttcaatcgt agaaagctgc gcacgaacgt tcttttccag ctgtcccgat
    33121 aacccctcga cctgtagacg gacgttcgcg gcgacggcag atccgcttaa gcagagtaag
    33181 cttacacagc ataactgtcg gatatagcgc acattttctc ctgaatatcc ttttttcctg
    33241 cccctggaac gccgttaaac ggcttaacaa aaatccagta atatggatta aaaagcagac
    33301 taacccccaa atatttctta tgttttactt tagacctatt cacggtggtt attgtgtgca
    33361 aatacgcctc ttgttacaac cttaacccca atgaccgatt ttcgggagag cgacaccatg
    33421 agtttatttg ataaaaagca tctggtttcc cccgccgatg ccctgcctgg acgtaacacc
    33481 ccgatgcccg tagccacgct gcatgcggtc aacggtcact caatgaccaa tgtacctgac
    33541 ggaatggaga ttgccatttt tgcgatgggt tgtttctggg gtgtggagcg tctgttctgg
    33601 cagttacccg gcgtttacag caccgccgca ggctataccg gaggctatac gccaaatccg
    33661 acttatcggg aagtgtgctc cggtgatacg ggtcatgccg aagcggtacg cattgtttac
    33721 gatccttccg tcatcagcta tgagcagttg ctacaggtat tttgggagaa tcacgatccc
    33781 gcccagggaa tgcgtcaggg caatgaccac ggcacgcagt atcgttcagc gatttatccg
    33841 ctgaccccag aacaggatgc cgcagctcgc gccagtctgg aacgttttca ggcggcgatg
    33901 cttgccgccg atgatgatcg tcacatcacc acggaaatcg ctaacgccac accgttttat
    33961 tatgccgaag atgaccacca gcaatatctg cataaaaacc cgtatggtta ctgtggaatt
    34021 ggcggaattg gcgtctgtct gccaccggaa gcatagcgtt acgggtacaa atgtagattg
    34081 ttgataaagt gcgctttatt tatgccagat gcggcgtaaa cgccttacca ggcctacaaa
    34141 atcgtccaaa ttcaatatat tgcaaggact gcgtaggcct gattggcata gcgcatcagg
    34201 cagtattgca tttatcagca gtctgaattt taaccctctg gcgactttac agtaccttac
    34261 gctatactag ccactgaaaa tgccggttca ctttcttcga atcggctttc aatgtgtatt
    34321 tcacacaaat taatcaactt ccccttccga ggatctggcc tgaaaggtcg gataagatat
    34381 gttaaacagt attttagtca tactctgctt gatcgctgta agtgcgttct tctcgatgtc
    34441 cgagatctca cttgccgcct cacgcaaaat caaacttaaa ctgctggctg atgaaggcaa
    34501 tataaatgcc caacgcgttc tgaatatgca ggaaaatccc ggcatgttct ttaccgtggt
    34561 ccaaatcggt ctgaacgcag tggcgattct cggcggtatc gtcggtgatg cggcattttc
    34621 tccagctttt cacagcctgt tctcccgcta tatgtcggca gagctctctg agcaactgag
    34681 ctttattctc tctttctcgt tagtgactgg catgtttatc ctgtttgcgg atttaacccc
    34741 gaaacgcatc ggtatgattg cgccagaagc tgtcgctttg cgtatcatca acccgatgcg
    34801 cttctgcctg tacgtttgca ccccgctggt gtggttcttc aacggactgg cgaacataat
    34861 cttccgtatt ttcaaactgc caatggtacg taaagatgac atcacttctg atgacatcta
    34921 cgcggtagtg gaagccggtg cgctggcggg cgtgttacgt aaacaggaac acgagctgat
    34981 tgaaaacgtc tttgagctgg aatcccgtac cgttccgtcg tcaatgacac cgcgtgaaaa
    35041 cgtgatttgg tttgatctcc acgaagatga gcaaagcctg aagaataagg tggcggaaca
    35101 tccgcactct aagttcctcg tctgtaatga agatattgac cacatcatcg gctatgtcga
    35161 ttctaaagac ctgctgaacc gcgtgctggc taaccaaagc ctggcactga acagcggcgt
    35221 acaaattcgc aacacgctga ttgtgccgga tacgttaacc ctttcagagg cgttggaaag
    35281 ttttaaaacc gcaggtgaag acttcgcggt gatcatgaac gagtacgcgc tggtggtggg
    35341 gatcatcacc ctcaatgacg tgatgaccac gctgatgggc gatctagtcg gtcaggggct
    35401 ggaagagcag attgtcgccc gtgatgagaa ctcatggctg attgacggcg gcaccccaat
    35461 tgacgacgtc atgcgcgtgc tggatattga cgagttcccg cagtcgggca actacgaaac
    35521 catcggcggc tttatgatgt ttatgctgcg taagatcccg aaacgcaccg attcggtgaa
    35581 attcgccggc tacaaatttg aagtggtgga tatcgataac taccgcatcg accagctgct
    35641 ggtgacccgg atcgacagca aggccaccgc cctttcgcca aaactgcctg acgctaaaga
    35701 taaagaagaa agcgtcgcgt aacccccaga aacatcaacg gctcctgaat caggagccgt
    35761 cttattactg catagcactt tggttaagcc atctctgttt gcagacgcat aacctgacgg
    35821 ttaacttcgg acatcactga caaatgcagc ttatccttca cttttgggat aagaatctta
    35881 cccttatcaa attcaaaagc gccaacgtcc ttgatgtata accgtccacg gaacaggatc
    35941 tttacgtact tcgccacctg aagtgggttg taccgttgga aaattttcat tgttatctcc
    36001 tgctgagtat tacgcctgtg cggtgccaca atcggcccaa ctattatgag gcgcaaattt
    36061 taatgcttag tgactataga ctatccgggc aatgtttcca ccgcgtataa ctttttttac
    36121 ctaaaggtta caattattca gaattatctt tttaccgaag cgcggtcttc agtataagca
    36181 ttcatttttc atatgatttg tgcgcttgac cgcaaactgg catcacactt gcgggaaatt
    36241 cgataaatag cacatatgat taaaactcag acccaagtgg tcggatcacc tgcatatcat
    36301 aagaaggaaa caccatgacc ctacgcaaga ttctggcact cacctgcctg ctgttgccga
    36361 tgatggcttc cgcacatcag ttcgaaaccg gtcagcgagt gccgccgatt ggcattaccg
    36421 atcgaggcga gttggtgctt gataaagatc agtttagcta caaaacctgg aacagcgcac
    36481 agttagtggg aaaagtgcga gtactgcaac atattgctgg tcgcacctct gcaaaagaga
    36541 aaaacgcgac gctgattgaa gcgattaaat cagcgaagtt accgcacgat cgctaccaga
    36601 ccaccaccat tgttaacacc gacgacgcga ttccgggttc agggatgttt gtgcgcagca
    36661 gtctggagag taataaaaag ctttatccct ggtcgcagtt tattgtcgat agcaatggcg
    36721 tcgcgcgcgg tgcctggcag ctggatgaag aaagttccgc tgtagtggtg ctggataagg
    36781 atggtcgcgt gcaatgggcc aaagacgggg cgctcacaca ggaagaggtg cagcaagtga
    36841 tggacctgct gcataaatta attaataaat agacactctg aatcccggat tcaggaacga
    36901 ctcgcgcgga gtgtaatcca gcggtttacc ctgccagtca tgaacgtgcg ctccggcagc
    36961 tgcagccaca gcatgaccag cggcggtatc ccaaatattc gttggtccga agcgcgggta
    37021 cagctgcgcc tgcccttccg ccaccaggca gaatttcagc gaagagccga tggacgtggt
    37081 ctgatgttcg ccaagctgtt gcagatactc tttcagctcc gcatctgcat gggaacggct
    37141 gataaccacc agcggcgggc gcgcatcgcg gacctgaatc tgcttgcgca caccgcactc
    37201 ttctttccag gccttgcctt ctgccgcgct gtacattatg ttcattaccg gcgcatacac
    37261 cacacctaaa atcggtttgc catggtcaat gagcgcaatg ttaacggtga attcgccatt
    37321 acgtttaata aactctttag taccatccag cgggtctacc agccagtaac gctgccagtg
    37381 ctgacggact tcccaaccgg gaggatcttc ttcagaaagg accggaatat ccggtgtcag
    37441 cgtacgtaaa ccgtccatga taacggtgtg agcggcaata tccgctgccg ttaccggaga
    37501 attgtccgct ttgctgacga cgtccatcgg tttcgtcccg tcgtagacct gcataatggc
    37561 atcgcctgca ttccgtgcaa gctggcatac ttgatctaac atttctccac ctcgtctctg
    37621 tgagcggtgt taacttattg ttttacttat accctatcgt taatgaatgc gccaactgtg
    37681 atagtgtcat cattttcaaa gcgtaaaatt gtggcattct tcactgttct ataagtaagg
    37741 cgtttattct cccttttctt tcgtattccc gatgataaaa ggatgtccct gatgattaag
    37801 tttagcgcaa cgctcctggc cacgctgatt gccgccagtg tgaatgcagc gacggtcgat
    37861 ctacgtatca tggaaaccac tgatctgcat agcaacatga tggatttcga ttattacaaa
    37921 gacaccgcca cggaaaaatt cggactggta cgtacggcaa gcctgattaa cgatgcccgc
    37981 aatgaagtga aaaacagcgt actggtcgat aacggcgatt tgattcaggg gagtccgctg
    38041 gccgattaca tatcggcgaa aggattaaaa gcaggtgatg ttcatccggt ttataaggcg
    38101 ctgaatacgc tggattatac ggtcggtaca ctcggcaatc atgaatttaa ctacggtctg
    38161 gattacctga aaaatgcgtt ggcgggagcg aaattccctt atgtaaatgc caacgtcatt
    38221 gacgccagaa ccaaacagcc aatgtttaca ccgtatttaa ttaaagatac cgaagtggtc
    38281 gataaagacg gaaaaaaaca gacgctgaag attggctata ttggcgtcgt gccgccgcaa
    38341 atcatgggct gggataaagc taatttatcc ggaaaagtga cggtgaatga tattaccgaa
    38401 accgtgcgca aatacgtgcc tgaaatgcgc gagaaaggtg ccgatgtcgt tgtcgttctg
    38461 gcgcattccg ggctatctgc cgatccgtat aaagtgatgg cggaaaactc agtttattac
    38521 ctcagtgaaa ttcctggcgt taacgccatt atgtttggcc atgctcacgc cgttttccca
    38581 ggtaaagatt ttgctgatat cgaaggggct gatatcgcga aaggcacgct gaatggtgtt
    38641 ccggcggtaa tgccgggcat gtggggcgat catcttgggg tggtcgactt acaactcagt
    38701 aataacagcg gtaaatggca ggtgacgcag gcgaaagcgg aagcacggcc gatttacgac
    38761 atcgccaata aaaaatccct cgcggcggaa gacagcaagc tggtagaaac actcaaagcc
    38821 gatcacgatg ccacacgcca gttcgtcagc aagccaatcg gtaaatccgc cgacaatatg
    38881 tatagctatc tggcgctggt gcaggacgat ccgaccgtgc aggtggtgaa caacgcgcaa
    38941 aaagcgtatg tcgagcatta cattcagggc gatccggatc tggcaaaact gccggtgctt
    39001 tcagctgctg caccgtttaa agttggtggt cgcaaaaatg atccggcaag ctatgtggag
    39061 gtggaaaaag gccagttgac cttccgtaat gccgccgatc tttatctcta ccccaatacg
    39121 ctgattgtgg tgaaagccag cggtaaagag gtgaaagagt ggctggagtg ctccgccgga
    39181 cagtttaacc agattgatcc tgacaacacg aaaccacagt cactcatcaa ctgggatggt
    39241 ttccgcacct ataactttga tgtgattgat ggtgtgaatt atcagattga tgttacccag
    39301 cctgcccgtt atgacggcga gtgccagatg gttaatgcca atgcggaaag gattaagaac
    39361 ctgaccttta atggcaagcc gattgatccg aacgccatgt tcctggttgc caccaataac
    39421 tatcgcgctt acggcggcaa atttgccggt acgggcgaca gccatatcgc ttttgcttca
    39481 ccggatgaga accgctcggt gctggcagcg tggattgctg atgagtcgaa acgtgcgggg
    39541 gaaattcacc cggcggcaga taacaactgg cgtttagcac cgatagctgg cgataagaaa
    39601 ctggatatcc gtttcgaaac ctctccatca gataaagccg cggcgtttat taaagagaaa
    39661 gggcaatatc cgatgaataa agtcgcgacc gatgatatcg ggtttgcgat ttatcaggtg
    39721 gatttgagta agtaatacac ttctttttcg gcctataaat catcaaccgc atccggcact
    39781 tttgtcggat gcgatgctgg cgcatcttat ccgccctaca agtcatgaac cgtaggccgg
    39841 ataagcgcag ccggcagtta tgccgcacgt tcatcccgca ccgccaacac ctcgggcaaa
    39901 ttcaactcaa tccagtccgc cagtgcagca accttttcgc tcacctgctc gcccagcggc
    39961 gtgaggctat attccacatg cggcggcacc accggatacg cgatacggtt aagaaaacca
    40021 tcctgttcta acgcctgtaa cgactgcgca agcatctttt cactcacccc accgattttg
    40081 cgccgcaggt cgctaaagcg atgagtacct tcgcgtagcg ccaccagaat caacaccccc
    40141 caacggctgg tgacgtgttt caacacctcg cgcgacgggc actgttccgc aaagagatta
    40201 ccctctttca gttgttgtga caggctaacc tgactcattt catacttacc tttttgtacg
    40261 tacttactaa aagtaagttt aggtgttagc gtatttaaac acaagacaaa acgatggaga
    40321 cttcccatga tcgctattac tggtgccact ggccaacttg gtcactatgt tattaaatcc
    40381 ttgatgaaaa cggttcctgc cagccaaata gtggctatcg ttcgtaatcc ggcaaaagcc
    40441 caggcactga cagcacaagg cattaccgtg cgtcaggctg actacggcga tgaagccgca
    40501 ctgacatctg cacttcaggg agtggaaaaa ctactgctga tctcttccag cgaagtgggt
    40561 caacgtgccc cgcagcatcg taatgttatt aatgccgcaa agacggctgg cgtgaaattt
    40621 atcgcttata ccagtctgct tcacgcggat aaatctccgc tcggcctcgc cgatgagcac
    40681 atcgagacgg agaaaatgtt ggctgattct ggcatcgttt acaccctgct gcgcaacggc
    40741 tggtacaccg aaaactatct cgccagcgcc ccggcagcac tggagcacgg cgtatttatc
    40801 ggtgccgcgg gcgatggcaa aattgcctcg gcaacgcggg cagattatgc ggcagctgcg
    40861 gcacgcgtga ttagcgaagc cggtcacgaa ggcaaggttt acgagctggc gggcgatagt
    40921 gcctggacgt tgacacagtt agcggcagag ctgaccaaac agagcggcaa acaggttacc
    40981 tatcaaaatc tgagcgaaac cgatttcgct gcggcgctga aaagcgttgg cctgcctgac
    41041 ggactggcgg atatgctggc ggattctgac gttggcgcat cgaaaggcgg tctgtttgat
    41101 gacagcaaaa cgctgagcaa attgattggc cgcccaacga caacgttagc cgaaagcgta
    41161 agccatcttt ttaatgttaa taaatagtta attaaagtgg catcctcccg catcctctct
    41221 gataatgacg ggatgccggg agcaatcatg tctgcttcct gaacgtttct tctgacagac
    41281 caatggatgc cagtaatgat tagcggcgtg ctgtacgccc tgttagcagg gttgatgtgg
    41341 gggcttattt ttgtcgggcc gttgatcgtg ccggaatacc cggcgatgtt gcagtcgatg
    41401 gggcgttatc tggcgttagg gttaattgcg ctacccattg cctggctggg acgcgtgcgt
    41461 ctgcgtcagt tggcgcgtcg cgactggctt accgccttga tgctcactat gatgggcaac
    41521 ctcatctatt acttctgcct tgccagtgcc attcaacgta ctggcgcgcc tgtttctacg
    41581 atgattattg gcaccctgcc ggtggtcatt cctgtctttg ccaatctgct ttatagccag
    41641 cgcgacggca aactcgcgtg gggaaaactc gccccggcac tgatttgtat tggcatcggc
    41701 ctggcgtgtg tgaatattgc tgagttaaac cacggactcc ccgattttga ctgggcacgt
    41761 tatacctctg gcatcgtgct agcgttagtt tccgtggtct gctgggcatg gtatgccctg
    41821 cgcaacgccc gctggctgcg ggaaaatccc gacaaacatc cgatgatgtg ggcgacggcg
    41881 caggcgctgg tcacgctgcc ggtttctctc atcggctatc tcgtcgcctg ttactggctg
    41941 aatatacaaa cgccggactt ctccttacct tttggccccc gtccgctggt gtttattagt
    42001 ctgatggttg cgatagccgt gctttgctca tgggttggcg cactctgctg gaacgtcgcc
    42061 agccagcgat taccgacagt gattctcggg ccgctgatcg ttttcgaaac actggcaggt
    42121 ttgctgtaca cctttttgat acgccagcaa atgccgccgc tgatgacgct gagcggtatc
    42181 gcgctgttag tggttggcgt ggtcattgca gtcagagcaa aaccggaaaa gcctttaact
    42241 gaatctgtct cagaaagttg acatactggc agtgagttaa ataagcctct gctacgtaag
    42301 ggttatagca tttgccttaa agatgcattt aaaatacatc ttatcttatt aagaatgagg
    42361 tatcagctat ggcttatcgc gaccaacctt taggtgaact ggcgctctct atccctcgcg
    42421 cttcggctct gtttcgtaaa tatgatatgg attactgctg cggcggtaag caaacgctgg
    42481 cgcgtgcggc ggcacgtaaa gaactggatg ttgaggtcat tgaagctgag ctggcaaagc
    42541 ttgctgaaca accgattgag aaagactggc gtagcgcccc gctggcagaa atcatcgacc
    42601 atatcatcgt gcgctaccac gatcgtcacc gcgagcaact gccggagctg atcctgcaag
    42661 cgactaaagt cgagcgcgtt cacgccgaca aaccgagcgt gccaaaaggg ctgacaaaat
    42721 acctgaccat gctgcatgaa gagctttcca gccacatgat gaaagaagag cagatcctct
    42781 tcccgatgat caaacaaggc atgggcagcc aggcaatggg gccaatcagc gtaatggaaa
    42841 gcgagcacga tgaagcgggc gaactgctgg aagtgatcaa acacactacc aataacgtca
    42901 caccgccgcc agaagcctgc accacctgga aagcgatgta taacggcatt aatgaactga
    42961 ttgatgacct gatggatcac atcagtctgg aaaacaatgt actgttccca cgcgcgctgg
    43021 cgggtgagta atctaaaagc tggatggcat tgcgccatcc agcatgataa tgcggttatt
    43081 tccgcagttc agcagcccgc ttcttaccaa taaacaacca gcccagcccc agtgcgataa
    43141 accacagcgg ggtgaccaac agcgcctggc gagtgtcatc ttccagtgtc agcaacacga
    43201 ccacgaacac aaagaacgcc atacataccc agcacatcag cttgccgagc ggcatcttgt
    43261 agatcgactt ctcatgcaga tgaggacgct gtttgcggta aaccaggtac gagcaaagga
    43321 taatcgtcca gacgaacata aacagaatcg cggaaacggt tgtaatcatc gtgaacgcgc
    43381 caatcacgct aggattcaca tacagcatca ccacgccacc gagcaggcag atgcaggaga
    43441 aggtcagccc tttcgctggt actgcgcgct tagaaagttt agcgaacgct ttcggtgcca
    43501 caccttcctg cgccagacca aacagcatac ggctggtaga gaagacgccg ctgttagcgg
    43561 aagacgccgc agaggtcagc accacaaagt tgatcacgct tgcggcagca ggcagcccta
    43621 ccaacacgaa cagttcaaca aacgggcttt tctccgggac taccgaactc cacggcgtca
    43681 cggacataat cacaatcagc gcgaagacgt agaacataat gatacggatc ggaatggagt
    43741 taatcgcgcg tggcagtgat ttctccggat ctttggtttc cgcagctgtt gtacctacca
    43801 gctcaatccc cacgaaagcg aaaaccgcta tctggaatcc ggcaaagaag ccacttaaac
    43861 ctttcgggaa ccagccgccg tcattccaca aatgcgcgaa tgacgcttcc acaccggtcg
    43921 gtgactgaaa gtgcatcgcc accatgacca ggccgacgac aatcagcgac acgatggcga
    43981 cgattttgat catcgcaaac cagaactcca tctcaccgaa cattttcacg gtggcaaggt
    44041 tgagcgtcaa cagcagcact atcaccgcca gcgaggcgac ccagtcggag agatcgggga
    44101 accagaactg agcataagca gtgatcgcca ccacgtctgc cataccggtt acaacccagc
    44161 agaaccagta agtccagccg gtgaaatatc ctgcccacgg cccgagtaaa tcggaagcga
    44221 agtcactaaa agatttgtat tccagattcg aaagcagcaa ttcccccatt gcccgcatca
    44281 cgaaaaagag cataaaaccg atgatcatat aaacgaaaat gatcgacggc ccggcaaggc
    44341 taatcgtttt gccagacccc ataaacaacc ccgtaccaat ggcaccgcca atggcaataa
    44401 gctgaatatg tcggtttgtg agattgcgcc gtagcgactg ttcagccgga gcctgatcat
    44461 cggcaacgac ttttacctga tctaccatgt ttttttcttc ctgtacctgt ctgtgttgtt
    44521 caggctctac ggcctttagt cagtctatga tacgacgaat ctgtatcggg actcatcgat
    44581 attaggtaac aatacgcggg atgaatacta agatttagat ctaatgttaa ttttatgttt
    44641 aaagtgagtg tcatatcacg gtgataacgc gaaacagctc acaaaaatac acgcttacgg
    44701 ggtctttgca acacaaaata gcgccgtttg gcaaactgaa gggtttattg ctgaatgcct
    44761 gctcccctct ggttcgaggg gaacagaatg cgctgcttag aggatttcca gcagttcgac
    44821 ttcaaacacc agggtgctga acggagggat ggatgcgcct gcgccgcgct cgccatatgc
    44881 cagttcctgc gggatagtca gttcccattt agaacctacc ggcatcagag tcagtgcttc
    44941 aatccagcca gggatcacgc cattaaccgg gaattcagcg ggttcaccac gagcaacgga
    45001 gctgtcaaac acggtgccgt cgatcagttt accggtgtaa tgaacacgaa cgcggtcagt
    45061 acgtgccgga attgcgcctt caccctggtt gatcacgcgg aattgcaggc cagattcggt
    45121 gctgttcaca ccttcttttt tggcattttc ttcaagatat ttcacacctt cggcagccat
    45181 cgcctggaaa cgctgacgac gaacggcatc ggcgcgttcg tggatttcac gcagcgcgcg
    45241 atgcaccaca tcaaccggaa cagccggatg tttgccttcc agcgcatctg caataccagc
    45301 caccagcgcc tccggcagca gcccttgcag gccagattca ctcagttgtt ggcctacctg
    45361 taaaccaatg ccgtagcttg cttgcgcttc gatggtgtca aaagttgggg tggtcatcgt
    45421 atttcctttc ttagggtata aaagtagcgg gcagcatatc agccacactt ctttgggtaa
    45481 aactttgtcg caggaatgat gacaaatccc ggggaaaaag aaacaatagc aatatcccgt
    45541 atgaatataa taaaggcggg tttaccacgg acatcatagc gttagcttat tcataggcta
    45601 tgattgagga acaagacgcg gagcaggagg aaaccatgcc cgggcgcttt gaactaaaac
    45661 caaccctgga gaaagtctgg cacgcgccgg acaattttcg cttcatggac ccgctgccgc
    45721 cgatgcatcg tcgggggatc attattgccg ccattatatt ggtggtcgga tttctgcttc
    45781 catctgatga tacgcccaac gcgccggtgg tgacgcgtga agcgcagtta gatattcagt
    45841 cgcaatcaca accgccgaca gaagaacagc tgcgggcgca attagtcaca ccacaaaatg
    45901 atcctgatca ggtggctccg gtcgctccag aacctataca ggaaggccag ccagaagaac
    45961 agccgcaaac tacccaaaca caaccattcc agccagatag cggaattgat aatcaatggc
    46021 gctcttaccg tgtcgaaccc ggtaaaacga tggcgcagct gttccgcgac cacggactgc
    46081 ccgctaccga tgtctatgca atggcgcagg tagaaggcgc gggtaagccg ctgagtaatt
    46141 tgcaaaacgg gcaaatggtg aaaatccgcc agaacgccag cggcgtggtg acgggcttaa
    46201 ccattgatac ggggaataat caacaggtcc tgttcacccg ccagccggat ggcagtttta
    46261 ttcgtgcgcg gtagatgaag ggtcaaccaa aagccagcta aggattgtct ctttgatgac
    46321 cttacgtctg gcttccagtg cctgggggga aaccatactg atatgataaa ccaggccaag
    46381 cgtatgctgg ttgatcaaat aatatccgcc aagcgcagca atattaatat tcacctgcaa
    46441 tgggtcgata tctggcttaa aaatattgtg tttcttccct tcatccaata aggattccat
    46501 taactgcaag tgcgcatggt taatttctaa gagacgctgt gattttgcat aatgcacacc
    46561 tttactttga ttttcactat gcacaatttt taaaaaccag ggattagtaa tataataatc
    46621 ccatgtaaaa tcaataattt tctcaatggc tttttgtggc ggaagatctg agaaatcaag
    46681 ggccttttct ttttgtcgaa tatcgttcca ggtatattcc agtacttcaa taaataaatt
    46741 ttctttatta ccaaagtgat gataaaccgt ctgtttacta caccccgcag ccttaacaat
    46801 attatcgacc ctggcccctt cataaccata ttcggcaaat tcattaaccg cgcataacag
    46861 cagcttttcc ttcaggctct gtacgttgct ggtatcaaga tacataactc ttccccacga
    46921 cctcttcaag ataactatct taacccgatt aattagaagc tccagtaaaa aggataaaaa
    46981 cttgtacttt catcaagtta tcaaatgtcc tgtgatcact atcgcatatc aaccaaccag
    47041 atggttgatc tttcttgcgg cacgtcgcaa gctaattgtc acttagaaaa caatattcaa
    47101 aaaaagagag ctattgtatg aaatccactc gtcctgttgc cgtgattacc ggagccgctc
    47161 gtggtattgg aaagggctgt gcgctggagc ttgctcgtgg cggatttaac ctgctgatta
    47221 acgatcttcc cgatgccgac agcgtagaaa aactgcatat cacacaacaa gaatgtatag
    47281 ctgaaggcgt ggaagtgatt tgcttccctg ccgatgtcgg cgatctctcc ttgcatgaag
    47341 agatgctcga cgcggcgcaa aacctgtggg gacgtctgga ctgcctgctc aacaacgcag
    47401 gcatttcagt gaaaaaacgc ggtgacctcc tcgacctcga accagacagc ttcgatcaaa
    47461 acattgccat taacacccgc gcgccgttct tccttgctca ggcattcagt aagcgcttac
    47521 tggcacagcc gaaaccggaa gcggagctgc cgcaccgctc gattattttc gtcagttcca
    47581 tcaacgccat catgctggcg atgaatcgcg gcgaatacac cattgccaaa accgccgttt
    47641 ctgccgctgc tcgtctgttt gctgctcgcc tttgtaatga acaaattggc gtttatgaag
    47701 tgcgccctgg tctcatcaaa accgatatga ctattccagc aacggcttat tacgacgaac
    47761 tgattgccaa aggtctggtg ccgtggggac gttggggtta tccggctgat attgcttcca
    47821 ccgtccgcgc gatggcggaa ggtaaactga tttacacctg tggtcaagcg gtcgccatcg
    47881 acggcggctt aagtatgccg cgcttctgag gctgaatcat gagagatctg ttacaacgcc
    47941 cggatttatt cagtatcaat accgcgacac tgggctataa aacgccgcta cccgccatta
    48001 ttgatgcctg cgccgcacgc ggtattggcg caattgcccc ctggcgcagg gagttgcagg
    48061 gtgaagatct ccagcaaatc gcccgccagc ttgccgccag taacatgagc gtttccggtt
    48121 tgtgccgtag cacttactac accgcgccga cactggcgga acgcaaactg gcgattgatg
    48181 ataaccgccg ggcgctggac gacgcagcgg tccttaacgc cgcctgttat atgcaggtgg
    48241 ttggcgggtt accgcaggga acaaaagatt tgtacgaagc gcgggaacaa gtaaaacaag
    48301 ggattcgcca gttgctgcca cattcgaaag atgtcggcgt gccaattgcg ctggagccgc
    48361 tgcacccgat gactgctgcc gaccgctctt gcctgtgcac gttacgtcag gcgctggact
    48421 ggtgtgatga actcgatccc gatggtgagt ttggcctcgg cgtggcggtg gatgtttatc
    48481 acgtctggtg ggatccggag ctcgccagtc agatcctgcg tgccggaaaa cgcatcctcg
    48541 cgtttcatgt ttccgactgg ttagtaccga ccaccgatct ggtcaatgac cggggaatgc
    48601 cgggagatgg cgtcatcaat attccgtcaa ttcgtcggct ggttgaaaac gccggattta
    48661 atggcgctat agaactggaa atattctcgc cttactggtg gcagaaagat attaacagca
    48721 cgctggatat tagcgtcgat cgcatcgcgc attattgtta aggaatgatc atgagtgacc
    48781 aacccgttct gttcagcaga gcggcggctt cttgccgcct gacattgaac cgtgaagata
    48841 aatgtcatgc tattaatgaa gaaatgatcg aatctctcga ccattattta aatgaaattg
    48901 aaaacgacac cacattacga ttagtcgaat taacggcaac cggcgataaa ttcttttgtg
    48961 cgggtggcga tattaaatcg tggtcggcct attcgccatt agatatgggc agaaaatgga
    49021 ttaaacgcgg taatgacgtt tttaatcgcc tgcgaaactt accccaatta accgttgcga
    49081 atctcaacgg tcataccatc ggcggtggta ttgaactggc cttgtgctgc gatattcgta
    49141 ttgcccgccc cggcgcgaaa ttctctaacc cggaagtgat gctcggcatg gtgcctggct
    49201 ggatgggcat tgaacgtgtg cttaatcagg ttggtccggt ggtcggtcgc cagatgctga
    49261 tgctgggtaa acgcctgacg gcgcaggaag cccaggcggc gaatttaatt gatgaagtgg
    49321 tagaaaaaga acaggtggaa agctggatgg cgaaccagtt agcgcagctg gaaaaatgcg
    49381 gtccggtggc actggcgcat attaagcaac tgattctggc actggaaaat aaacatgccg
    49441 attacccgca ccagctactg gccggattaa tgtctgccac tcaggattgc cagcaggcga
    49501 cgcgcgcctt tgccgaaaaa agtagcgtga gcttccataa tcaataagga aattgtatgc
    49561 gtaagataac aaccgccgag gcactggcgg cgcaaattca ggacggtgcg actattgcta
    49621 ttagcggtaa cggcggcggt atggtagaag ccgaccatat tctggctgct attgaagcgc
    49681 gtttcctgca aaccggacac cctcgcgacc tgacgctaat ccactcgctg ggtattggcg
    49741 atcgcgactg caaaggcact aatcgttttg cgcacgcaga gatgctcaaa cgcattattg
    49801 ccgggcactt tacctggtcg cccaaaatgc aggcgctggt aaaaaataac acgattgaag
    49861 cctactgctt tcctggtggc gtgattcagg cactgctacg ggagatcggc gccggacgtc
    49921 cggggctttt tacccacgtt gggctgggat cgtttgttga tccacgcaat ggcggcggta
    49981 agtcgaatga atgcactacc gacgacctgg tagaactgat tgaaatcgac ggtgaaacca
    50041 aacttcgtta tcgccctttc aaagtggatt acgcgatttt gcgtggcact tatgccgatc
    50101 ctcgaggcaa cgtcagcctt gaagaagaag cgattgatat ggatagctat tccatggcgc
    50161 tggcagcaca caacagcggc ggcaaagtgt tcgtacaggt acgcgatgtg ctggaagctg
    50221 gcgcgattga accacgccgg gtcaaattac cgggcattct ggttgatggc atcgttgaac
    50281 accgcgaaca accgcaaacc tatcttggcg gttacgacct gaccattagc ggtcaacatc
    50341 gccgtctgag ttctaacgac gctattgaac tggttagtca tccggtgcgc cgcctgattg
    50401 cccgtcgggc agcacgcgaa ctggtggctg gcgcttcaac caactttggc tttggtattc
    50461 ctggcggtat tccaggcgta gcgctgcgcg aaggcgttcc ttaccaaagt ttatggctga
    50521 gcgtcgagca aggcgtacat aacggcatga tgcttgatga tgctctgttt ggttgtgccc
    50581 gcaacgccga tgccattatt ccatcactcg atcaatttga gttctacagt ggcggaggga
    50641 tcgatatcac cttcctcggc atgggagaga tggatcagta cggtaacgtc aacgtctccc
    50701 atctcaatgg caatctcatt ggccccggcg gttttctcga aattgcgcaa aacgcccgta
    50761 aagtggtgtt ctgcggcacg ttcgacgcca aaggtagcaa gattgatgta acgccagatg
    50821 gcttgcatat cgcccagtca ggtcaaatcc ctaaactggt tacccaggtg gaaaaaatca
    50881 cttttagcgc cgcctacgca cagcaaagtg gtcaggaagt gttgtatatc actgaacgcg
    50941 cagtattcca gttaacggca gaaggcgttg aattaattga aatcgcaccg agtgtggaga
    51001 ttgagcgcga cattctgccg tatatggcct tccgtccaat tatcaagcat ccacgcctga
    51061 tggaaagtag cctgtttacg ccgatggagg atgcatgagt cagcttgatg acaccatcct
    51121 tgatgcgctg acgcacgtta ctttcccaaa gggttttgca caggcagagc ccgcatgggt
    51181 tgtcacggta gacggtgttg attacccact ctggcaaaca gatgccctgg tagtcggcag
    51241 tggtgcagcc gggctgcgtg cagctgtgga acttaaacgc cgccagcaaa atgtgctgat
    51301 cgccactgcc gggttatata tggggacgtc ggcatgttct ggttccgata aacagacact
    51361 gtttaccgcc gctaccgcgg gcaacggcga caacttcacc aaactggcag aggcactggc
    51421 gagcggtggg gcgatggatc acgacaccgc ttatgtcgaa gcggtaggtt ctctgcacac
    51481 tcttggcggg ttgcaatatc ttggtctgga attaccggaa gatcgctatg gcgcgattct
    51541 tcgttatcaa accgaccatg acgaagccgg gcgtgcaacc tcgtgtgggc cgcggacctc
    51601 aaggttaatg gtgaaagtgc tgttggaaga agtacagcgc ctcgccattc cagtgttgac
    51661 cagtgcaaca gtgattaaac tgctgcatca gcgtgacgaa aacggcgaag accgtgtggc
    51721 gggggcaatc ctcgcgaccg gtcatcgcgc ccataaccct tgggggctgg caattgtgac
    51781 tgcgcccaat gtggtactgg caacaggagg gcctggcgag ctttatcgcg acagtgtgta
    51841 cccacacaaa tgttttggct cgctggggct ggcgctggag gaaggcctga cgctaaccaa
    51901 tctgaccgaa agccagtttg gtataggcac gccgcgcagc acgtttccgt ggaatttatc
    51961 cggcacctat gtacaggtga tcccgtatat ctattccgtg gatgctgagg gtaacgagta
    52021 taacttcctc gcggattact atcgcaccac ccaggagctg gcttcaaaca ttttccgtaa
    52081 aggctatcag tggccgttcc acgccactcg ggtgatggat tttggctcca gcttgttaga
    52141 tatggcagta gcgcaagagc agcaatcagg gcgtcaggta tttatggatt tcaatcgcaa
    52201 tcctgaacct gtgccgggtg acctgccatt ctcattagag cgactggacg acgacgttcg
    52261 cgcgtatctg gaaaataacg acgctctggc accatcgccc atcgaacgac tgcaacgaat
    52321 gaatccgctg tctatctcgc tgtataagat gcacggttac gatctcacca cgcagccatt
    52381 gcagtttgcc atgaataatc agcacatgaa tggcggcatt gaagtggata tctggggaca
    52441 aacatccctg cccggttgtt ttgccgtggg ggaagttgct ggcacacacg gcatcactcg
    52501 ccctggtggt gcggcattga atgccgggca ggtttttgct gttcgtctgg cacgttttat
    52561 tggttgcacg caaaaacgta atattgatgg agatatagca cagctggtag ctcaggcact
    52621 ggcttctata agagagatca ttactcaggc gcacgataac gggaccggga tgccgttgtc
    52681 ggttgtgaga gaaaaaattc aggcacgaat gtctgaccat gcgggattta tttgccatgc
    52741 cgataaagtc cgacgcgcca ctcgtgatgc cctgctattg aacgaatttg tccaacggca
    52801 tggattggct atcaaacatg tgggcgaagt tgccgagctg tttatgtggc ggcatatggc
    52861 gctgacctct gccgccgtct taactcaact gacacattat attgatgctg gtggtggcag
    52921 tcgtggggca cggatagtta ttgatccaca aggcaaatgc ctaccacaaa ctcgtcgcgg
    52981 cgcaaaagaa gaatggcgtt ttcgctctga acgtgctgaa gacaaaaatc acagattaac
    53041 gattcaatat tcgcaaggtt cttttattac cgaagtgaag tctttacgta tgcaaccgtg
    53101 tattaacggt atttactttg aaaaaaactg gccagacttt ttaaatggag aaatttacac
    53161 acaataattt tcaatatttc ctctgtacct gatttttatt acctattaca cggaaacacc
    53221 aacaaccagg gtttattaat ataattaaaa ggtttaaaca tgaataaaat aaagaattac
    53281 cggtggcata tgattgccct cgtatgcttt atcactgtaa tcaattatct ggacagaacg
    53341 gcattaggta ttgcggctcc aacgattatg gagacaaccg gaataactaa agagcaatat
    53401 tcatggattg tcagtgcatt ccagttggcc tatacattag ggcaaccggt aatgggcttc
    53461 tttattgata ccgtgggtct gaagttaagt tttgcgatat gtgccgcaat ttggggcctg
    53521 gcgacaatgg gccatgcact caccggaacg tggtctggtc tggcatttat gcgcgccctg
    53581 atgggtttca gcgaagcgtc ggcaattccg gcgggtgtaa aaaccgcatc aacatggttc
    53641 ccggcaaaag agcgtggcgt ggcgacaggt gttttcaata tgggcacctc actcggcgcg
    53701 atgcttgctc caccgttgat tgcctggtgc attatgtttc atagctggca atttgcgttt
    53761 attgtttcag gtagccttgc tttgctcgcg gctttatttt ggttcttttg ttataaagat
    53821 ccgaaagatg ccaaacgcct ttctgatgaa gagcgccact atattgaatc aggacaagaa
    53881 cagcatctta aaacagataa gaaagaaaaa acgtcaatca agcatatcct cagccaacgt
    53941 aatttctggg ggattggcat cgcgcgtttt ctcgcagacc cggcatgggg aaccattaac
    54001 ttctgggtgc cgattttctt cgtcgaaacg ctgcatttta gcctgaaaga aattgccatg
    54061 ttcgtctggc tgcctttcct gctgggcgat ctcggctgtt tagccagtgg ttttgtcgcg
    54121 aagttcttcc acgatcgcgg cgtgagttta attaactcac gaagaattac cttcactatt
    54181 gcagccgtca ttatgatgac gattggcctg gtgagtattg tcgaaaatcc ctacattgcc
    54241 gtattactga ttagtattgg cgcgttctcg catcaatgtc tttctactgt agcagcaact
    54301 ctgggtggcg atctgttcaa aaaagacgaa gtagctaccg cagtgggtat ggcaggagcc
    54361 tgtgcgtgga gcggtcagtt gattttcaac ctgtttatcg gggcattcgt tcacattatc
    54421 ggcttcgcgc cgttctttat tgccctggct ttctttgaca ttattggcgc cattgcgctg
    54481 tggacgctta tcaaagttaa agatgaagaa ccgcaagtac agttagcgac aagctaatta
    54541 atagatatca gagcgttata ctaccagttg taacgctttc gctataaagc aaaacgccga
    54601 ccaatggtcg gcgtttttac gtctcgttga ataacgaatt attcagcaac tacgtttacg
    54661 atcactttcg cgaatacttc gctgtgaacc tggaagctca cttcgtgttc gccagtggta
    54721 cgcagaacgc cgttcggcag acgaacttcg ctcttagcca cttcaacgcc agctgcagtt
    54781 acagcgtcag cgatgtcgcg agtaccgatg gaaccgaaca gtttaccttc gtcgccagct
    54841 ttagacgcga tggtaacagt ttccagtgca ttgattttct cagcgcgagc attagcagct
    54901 gccagaactt cagccagttt agcttccagt tcagcgcgac gtgcttcgaa gaattcaatg
    54961 tttttcttgg tagctggaac agctttaccc tgcggtacca ggaagttacg agcatagccc
    55021 gctttaacgt ttacctgatc acccaggcta cccaggtttg ctactttatc aagcagaata
    55081 acttgcatta ccttatcctc tcaaagtcgt attaatggac cgtgaccgat tactgatggc
    55141 gatcagtgta cggcagcagg gacaggtagc gagcgcgttt gatagcgcga gccagctgac
    55201 gctggtattt tgcacgggta ccggtgatac ggcttgggac aatcttaccg ctttcggtga
    55261 tgtagttttt cagcgtagcg atatctttat agtcgatctc ttgaacgcct tccgcggtga
    55321 aacggcagaa cttgcgacga cggaaataac gtgccatatg gctagtctcc agaatctatc
    55381 aattcaatct gctcggcatg caaaaccatt ttgctcagtc cgttctttgc cttgtggcat
    55441 gaaatgaacc cctgaacggt tatgcgactg ccgaccgtta tactgtgagt aatggcctgg
    55501 ttttcgtgtc cgctaacaat aacgggcatt tgacaccatg cctgccggtg aaaaccggct
    55561 tcctcctgca cagaacgatg ctcaagcacg aactggcagt gaggaattcc tgatggactg
    55621 acctttcgaa ggggagtcct gcacacggtg ccggacaaca ccagacggtt ggtcatcaga
    55681 aattactctt cagaatcccc agcttcagca tcatcagcgg tttcgtttgc gaaatcatcg
    55741 cgacgctcac ggcgctcgtc tttcgcttta accattggag atgcttcggt aacagcgtgc
    55801 ttggtacgca taaccatgct gcggataacg gcatcgttga agcggaaggt agtttccagc
    55861 tcatcgatca cttcctgcgg agcttcaacg ttcatcagaa cgtagtgtgc tttgtgcagt
    55921 ttgttgatcg ggtaagccag ctgacggcgg ccccagtctt ccagacggtg gatcttgcct
    55981 tctgcaccag tgatggcagc agtgtagcgc tcgatcatgc ccggaacctg ttcgctctgg
    56041 tcaggatgga ccataaaaac gatttcgtaa tgacgcatcg aattgctcct tacggattat
    56101 tcagcctcct gtctgggtca gccgaatccc ggggaggcaa ggaacgtgtt aaaggtcggc
    56161 tgaaaaatga cgcgttatag tactgacata ccccgctaaa ctcaagggcg gagcagaaat
    56221 aaatctcccc tttcgcaaat aacctctaaa ccgctgattt gaagttcatc acattccgtc
    56281 acagtgtttt ttcgaacaac tgcatcagaa atggtcacca tcaacttctt tatcattgat
    56341 taaaattaaa tcagaagatc atcacagagg agagcacaca aagtcagccg tcgaggaggt
    56401 atctatgttc agtcgagttt tagcccttct ggctgtgctt ttgctaagtg caaatacatg
    56461 ggcagccatt gaaattaata accaccaggc cagaaatatg gacgatgtgc aaagcttagg
    56521 cgtgatttat atcaatcata atttcgccac tgaaagcgaa gcacgtcagg cattaaatga
    56581 agaaacagat gcgcaaggcg caacgtacta ccacgtaatt ctgatgcggg aaccggggag
    56641 taacggcaat atgcacgcca gcgcggatat ttatcgctag caccaggtat aaccaacgaa
    56701 acattgccat agtttgcttt gcccccttcg cagggggctt tttttgaaaa acggctgcgg
    56761 aattagacca gttatctccc gaggaaggaa atttccgcag cgcgtgtttt acttctgccc
    56821 gtaataagcg ttagggccgt gcttacgcat gaagtgttta ttcatcagga agctgtcgat
    56881 gtgattgagt tgtggattaa tactgcgcgc aatccacgcc attttcgcca cttcttccat
    56941 cactaccgcg ttatgcaccg cgtcgtgggc atctttcccc caggcgaacg gtccgtgctg
    57001 atacaccaca attcccggcg tatgcagcgg ctcggcgttg cccagcgttt cgataatcac
    57061 tttgccagtg ttcagttcat actcaccctg cacctcttct tcgcttaatc cacgcgtaca
    57121 cgggatatca ccaaagaagt agtcagcgtg cgtggtgcct aacgccggga tcgccagccc
    57181 cgcctgcgcc catgcggtgg catgagtgga gtgggtatgg acaatgccgc caagcgacgg
    57241 gtaacgacgg tagagttcga gatgcgtcgc agtgtcggaa gatgggcgat actccccttc
    57301 caccaccttg ccgctcatat caaccaccac catatcggcc gctttcatgg tttcgtaggc
    57361 aacgccgctg ggcttgatca ccaccagccc gcgttcgcgg tcgatagcgc tgacgttgcc
    57421 ccaggtaaag gtcaccagcc cgtagcgcgg cagctccatg ttggcttcaa atacctgctg
    57481 ttttagcttt tgcattatgc cgcctccacc atgcccgctt tcgccatgcg cgctttcacc
    57541 caatcacgcg ctttcgccac ttctgccgcc gggtcttccg ccgtttcgct ccacatctca
    57601 atcaggtacg gcccgcaata gccactctgt ttgagcgttt cgaaacaacg ttcgaaatcc
    57661 actacacctt cgccaaacgg cacgtttttg aagacgccag gtttggtgtc tttcacatgt
    57721 actgcgacga tatgcccgat tccggcctgc aactccatct gcacatcgtt gtcccacgcc
    57781 gacaggttgc cgatatccgg gtagagctgg aaccacggat tgttgagata gtgcgcgtag
    57841 cccagcgcct tgctgatgga gttcatcaac ggataatcca tgatctccat cgccagcgtc
    57901 acctgcgcgc ggcttgccat ctcaacgctc tctttcaggc cgtcacgaaa acgacgacgc
    57961 gtttcgttat tggcttcctg atagtaaacg tcatagcccg ccagctggat cacgcgaatg
    58021 ccgacgtcct gagcgaactg gatagcttta cgcataatct ccagcccctg cgcccgcacc
    58081 gcgtcatctt cgctacccag cgggaaacga cgatgagcag aaaggcacat tgacggtacg
    58141 cgtacgccgg tttcaacaat cgcgttcacc agcgccagac gctgatcgcg gctccagtcg
    58201 aggcgcgaca ggcgctcgtc cgtttcatct accgacatct cgacaaaatc gaagcccaac
    58261 gtttttgcca gttgcaggcg ttccagccag cactccccgg cggggagcgc tttttcatag
    58321 atgccaagcg ggatttgttt ggacaacata tccgctcctt agccccacag ttcggcgatg
    58381 gaacgtttga actgacgtgc ggcttccacc ggagaagcgg catcacggat actacggccc
    58441 gcgataaaga cgtgaatcgg aatgcctttg aacagtggca gatcttccag cgccaggcca
    58501 ccagtgacgg tcactttgaa gcccatatcg gaaagacgtt tgatcgcggt aatgtccgct
    58561 tcgccccacg ccacgcctgc ggcctgcgcg tcacggctgc ggtgataaac cacctgctga
    58621 atgcctgcgt cgcgccactg ctgcgcctgt tcccaggtcc agtagccggt cagttcaatc
    58681 tgcacgtcgc cgttaaactc ttttgctacg tccagcgcgc ctttggcggt gttgatatcc
    58741 gcacagcaaa ttaccgtcac ccagtcagca ttggcttcga agcacatacg agaaagaatt
    58801 ttgcccgcat cggcaatttt ggcgtctgcg agtacgattt tgtgcgggta aagcgctttc
    58861 agatcgcgaa ccgcacgcac gccttcgccc acgcacagaa tggtgcccac ttcgataatg
    58921 tcgacttctt cagcaatcag gcgagtggtt tcgtaggcgc tatccatagt ctggttgtcc
    58981 agcgcgactt gcaacatcgg taatgacatc ttcaattcct tcttaagctg ccgcgttggt
    59041 gcggtcaatg agatccagta cttcctgctc ggtacggcag gcacgtaaac ggtcgaaatt
    59101 ttcttcatct tcaaacaggt tgacgatctg catgatgcct acttcctggt gcgtgttggc
    59161 atcgaccgcc gccatggtga tgaggatatc cacagggtca ttatcttcgt ggttgaactc
    59221 cagcggcttt ttcagcgtca ctagcgcaaa accggttttc ttaacgccct cttccgggcg
    59281 accgtgcggc attgccaggc ctggtgcgag cacaaagtac ggaccgtgct gttcaaccgc
    59341 atccagaatc gcctggtagt aacgcggctc gacaacatcc gccgccacca gcaggtcaac
    59401 gccgattttc actgcgtcct gccatgtctc tgcttcagcc tgcaggcgga tggatttatt
    59461 ctccgccagc gaatcacgta atttcatggc gcgtccttac ttcacgtcct gcgggaaatg
    59521 ctctttgatc acttccagca gtttcgggcc aaagtcggca ggagagagca tgttgcgcac
    59581 gccgaccacg tatttgttgc cggtcacggt gatttcgccc gcaatgtgcg tagaagcgat
    59641 gatgatatcc gcgccgctca actcgctttt gtattcgcca accgcgcagc tgtttaccgt
    59701 gtggtcaatg tttgattggg ttaaaaactg gtccactttc atcttcatga tcatggaact
    59761 gccttgtccg ttgccacaca cagccagaat acgtacggtc ataatcaaaa ctccttatta
    59821 agcagactgt tctgccagtt gtttttctgc atcttcttct gcgcgcagtg cgcggccagc
    59881 gaagaacata taagccagtg caattacaat gatgacagcc ataaaggcga taccgatgga
    59941 gaagaagccc tgcatcatcg gcggtgccag aatcgaccag tccgccatac ccatccaggc
    60001 actcataccg gtaagtttca ccgcccagac gcaaccaaag atttcgatca tccccatcac
    60061 cagacaaatc ttcagcgccg cacgccagcc gccgaagtgg ttagcgaaca cgccgatggt
    60121 ggcgttggag aagaacatcg ggataaagcc gggaataatc aggatcgagg agccgcaggc
    60181 gaccaggatg ccaaccgcaa tcagctgacc gatggtgccc cacataaagc cccaaaccac
    60241 ggcgttcggc gcgaagctat agatagccgc acagtcaatc gccagaaccg cacctgggat
    60301 caggcgctga gagataccgt taaacgcttc agagagttcc gccacaaaca tgcgcacgcc
    60361 ctgagtgatg atgaagatcg ccaccgcgaa ggagaaaccg gtttgcagga tgtagaccgt
    60421 ccagttcact ttgcctgcca tcgtctgcac ggtgtcgata ccgaaggaga gcagaatggc
    60481 gccaaagaag atggtcatga caatcgccgt ggagacgatg ttgtcgtgga aaatgttcag
    60541 ccagccaggc agtttgagat cttcaacgct ctcctctttt ttgcccagga acggcgcgac
    60601 tttataagca atccatgatg caaactgctg ctggtgaccg atggagaaac cgcagccatc
    60661 cgtcacttcc tgagtcggct tgtacatcat attggaggta atgccccagt agagcgaaac
    60721 cagaatcgcg gtgcagataa tggtcgtcca catggaatag ccgaaaataa acaacgtaac
    60781 ggcaatcagc cccgcctgct ggaacatgat gtgaccagtc agcatgatgg tacgaatacc
    60841 ggtaatgcga cgcagcagca cgtaacagat gttcagtgcc agcgctaaca acaccgcgta
    60901 acctacccag ctataagcat cgcccatgcg ttcaatggtt gccatcatcg acgcgtaagt
    60961 atctgaaatc gcaccgttga tgccgtagac ttccgacatt ttcgccacca ccggtttgaa
    61021 ggtactggtc aggatgccgg accctgcctg caacaacatg aaaccaataa tggtttttat
    61081 cgtacctttg ataataacgc tgacactttt gcgcagcagg atatagccca gacaggtcac
    61141 aatacccagc agtaacgggg cattggtcat gacctggtta aaaaacacgg taaagatgtt
    61201 gtagaggatc tccataacga tctcctgaag aagaggtaac cgggtattcc gcacacccgg
    61261 aatgttgtgc actcactcta attttcaaaa gtaatcacaa caagattatt tatgattaaa
    61321 tgtgacgcga cccgcaaata attccacacg gatagagtgg gattcacaca acgaaacaat
    61381 tatttattta aattcattta gttaatttaa ctacacattc cattaaatct ttccacactc
    61441 aaaatcaaca acaacttccc tggcaaaaag tcaaaaaatg gtcattgcct tcctgaaaaa
    61501 atagtgtcag gattaatcaa aaccaatcac acattgattc gaattgaact atcatgaagg
    61561 taaatggcga tgagtaaagt gaaaagtatc acccgtgaat cctggatcct gagcactttc
    61621 ccggagtggg gtagctggtt gaatgaagaa attgaacaag aacaggtcgc tcctggcaca
    61681 tttgcgatgt ggtggcttgg ctgcaccggg atctggttaa aatcggaagg tggcaccaac
    61741 gtttgcgttg atttctggtg cggcactggc aaacaaagtc acggtaaccc gttaatgaaa
    61801 cagggtcacc aaatgcagcg catggctggc gtgaaaaaac tgcagccaaa cctgcgcacc
    61861 accccgtttg ttcttgatcc gtttgcgatt cgccaggtcg acgcggtact ggcgactcac
    61921 gatcacaacg atcatatcga cgtcaacgtc gctgctgctg tgatgcagaa ctgtgctgat
    61981 gacgtaccgt tcattggacc gaaaacctgt gtggatttgt ggattggctg gggcgtaccg
    62041 aaagagcgtt gcatcgtggt caaaccgggc gatgttgtaa aagtgaaaga cattgaaatt
    62101 catgcgcttg acgctttcga ccgtactgca ctgatcaccc tgcctgccga tcaaaaagcg
    62161 gctggcgtac tgccggacgg catggacgat cgcgcggtga actatctgtt caaaacgcct
    62221 ggcggctccc tgtatcacag cggcgactcc cactactcta actattatgc gaagcacggt
    62281 aacgaacatc agatcgacgt ggctttaggt tcatacggcg aaaacccgcg cggtatcacc
    62341 gacaaaatga ccagcgccga tatgctgcgt atgggtgaag ccctgaatgc gaaagtggtt
    62401 atcccgttcc accacgatat ctggtcaaac ttccaggccg atccgcaaga gatccgcgtg
    62461 ctgtgggaga tgaaaaaaga tcgcctgaag tatggcttca agccgtttat ctggcaggtt
    62521 ggcggcaaat ttacctggcc gttggataaa gacaacttcg agtaccacta tccgcgtggt
    62581 ttcgatgatt gcttcactat tgaaccggat ctgccgttca agtcattcct gtaatctgtc
    62641 gtttataccg gatagcgtgg agtagttcgc gctatccggc gtagtatttc ctggctattt
    62701 caaatatcat ctaaaaaaat caaattttat cggaatagct catgactgaa gcacaaagac
    62761 atcaaatcct cctggaaatg ctcgcacaat tgggctttgt gaccgttgag aaagtcgttg
    62821 agcgtctggg aatttcgcct gccactgcgc gacgcgatat caataaactt gacgaaagcg
    62881 gcaaactgaa aaaagtgcgc aatggcgcag aagctattac ccaacagcgc ccgcgctgga
    62941 cgccgatgaa tctgcatcag gcgcagaatc acgatgaaaa agtacgtatc gctaaagcgg
    63001 cctcgcagct ggttaatccg ggcgaaagcg tagtcatcaa ctgcggctcc accgcgtttc
    63061 tgcttgggcg ggaaatgtgt ggcaagccag tgcaaatcat cactaattat ctaccgctgg
    63121 caaattacct gatcgatcaa gaacatgaca gcgtgatcat tatgggcgga cagtacaaca
    63181 aaagtcagtc catcacttta agcccgcagg gcagcgaaaa cagtctctat gccgggcact
    63241 ggatgtttac cagcggcaaa ggactgacag cagaagggtt gtataaaacc gatatgctga
    63301 cggcaatggc agagcagaag atgctgagcg tggtagggaa actggtggta ctggttgata
    63361 gcagtaagat tggcgaacgc gcgggaatgc tttttagccg tgccgatcaa attgatatgc
    63421 tgatcaccgg caaaaatgct aacccggaaa tcctgcaaca actggaagcg caaggggtca
    63481 gcattctgcg tgtttaaaga tgctggcgga aaaatgtcac tgcagcatct aacgcctcag
    63541 gcgtaatgcg gtgacgcacg cctggctgcc atgaacaggt tagcagttta tcccgtcccg
    63601 tctcgcttaa ggcctgctgc aaacgtagtg attcgtcggc aggcacaacg tcatcgtcga
    63661 ggccatgcca cagcagtaga ggtctgtcac taagttgttc caggtggttt gtcgcttccc
    63721 actctgccag cggcgcgaca atgttattga attcattctg ctgtgctgtc gtttcaggta
    63781 tcagcggtgg aaacagtgaa cgggcgagtg atgtaaaata gcccgatccc atcatgctgg
    63841 cggtacatct caccgtgggg tggcgagcgg taatccccag tgccgtcatc gcgcccatcg
    63901 acgcaccacc gactgccaga cggtcatcaa gcagccactt ttcttcggct attgccgcac
    63961 gtaaagtagt gaattcctgc atactttgta gcaagatttg ccagaattga tttaaccgcc
    64021 gcgctgcgtc gccactaaaa cgactaccgt gatcgggcgc atccggcatg atcacccgca
    64081 aaccagcctg cgccagcgca acggcaaaat agctatacac cagactggac gaagtaaagc
    64141 cgtgataaaa aatcgcgcac ggtaacgggg tatctttttg tccgacagga taagcatgaa
    64201 gaacgggaat atctgccagc tcgcgtgatt ctatttcaat catctgtctc tcctttttgt
    64261 ctggtatgac atgaagaaat ccttagcaca agtttctgct ggcggtatta gttcataatg
    64321 ttgagatgtg ggttacgctt tcgtcacgtt ttcattcgaa aatcgcgtac caggtaacaa
    64381 ttcgggaaca ttcccccaaa gttaaattaa taaggcacta cactatggtt agcaggaaac
    64441 gtaatagcgt tatttaccgg tttgccagtt tattattggt gttgatgtta agtgcctgta
    64501 gcgcactgca aggtacgcca cagccagcac cgccagtaac ggaccatccg caagagattc
    64561 gccgcgacca gacgcaaggg ttacagcgaa taggtagcgt aagcacgatg gttcggggtt
    64621 ctccggatga cgcattagca gaaatcaaag cgaaagctgt cgctgcaaaa gctgattatt
    64681 acgttgtcgt catggtggac gaaaccatcg tgacaggaca gtggtattca caagccattt
    64741 tgtaccgtaa ataaatcaga caacttacat agtcagcttt acattgcttt gcgtccctat
    64801 gcgtttacct gtgcacaata aattaccggc tggaagcctg ggcgtttatt accgcgatgg
    64861 aatgccctgc aacatgtggg gaaacgaaaa atggagctga cgatgaaaca attacttgcc
    64921 tcaccctcgc tgcaattagt gacttatcct gcgagcgcca cggcacagtc tgcagaattc
    64981 gccagtgctg actgcgtgac gggcctgaat gaaataggtc agatctcagt tagcaatatt
    65041 tcaggggatc cgcaggacgt ggaacgtatc gtggcgttaa aggccgatga acaaggtgcg
    65101 tcatggtacc gcattattac catgtacgaa gaccagcagc ctgataactg gcgcgtacag
    65161 gcgatactgt atgcatgagt gtcatctaca gcaaatgaac aatgccggat gcggcgcgag
    65221 cgccttgtcc ggcctacaat tttcacatat ttcatttagt taatcgaaac cagcgtcgca
    65281 tcagtcgtat acgcttacac acacactccc cccgtcgccc gcagcaataa atcattctgg
    65341 atctcctctg acaaccgtac gccgccgcgc gtatctaaca tcacctgaca ccacgcctgc
    65401 gccattggcg gagaagcata tttcaacatt tgcgcaccgc agcccagcag gaatagctga
    65461 tgagtaatct ctcgccccag ttcttcagct ggcttacgca gctgctgctg taaacgacga
    65521 accgcgcgat caaaatagcg atcctgccct ttcacttcca caaatgcttc cgacaataag
    65581 tcgtatacgc ccgcttgctt attgagaacg cgcaacacat ccaggcacat aatattgccg
    65641 gaaccttccc aaatactgtt taccggcatc tcccggtaaa gccgcggcag ctcgctctcc
    65701 tcgcaataac caatgccgcc cagcacctcc atcgcttcgg ccacaaacgg catacctctt
    65761 ttgcagatca caaattttgc cgcaggcgta aataaacgcg cccacagggc ttctttggca
    65821 tcggcacgcc ggtcccacgc tcgcgcaaga cgaaacagca acgccgtttg cccttcaagc
    65881 tgaagtgcca tgcgacttaa gacatgacgc ataaggggct gttggatcaa tggattacca
    65941 aaaacatggc gttgatgtgc atgataaatc gccagcgaaa atgcacggcg catcatggca
    66001 tggctaccca gggcgcaatc aaaacgcgtc atcccaccca ttttcaggat cagacgaatt
    66061 ccttcccctt cctgccccaa caaccaacca atggcatcct gaaactccac ttcgcaactg
    66121 gcgttagagc gattacccag cttatctttc agccgctcga ggcgaatcgc gttgcgttgc
    66181 ccgtcaggca aaaagcgcgg cacaaaaaag caggacagac cacccgcggt ctgcgccagc
    66241 accagatgcg catcgctttg cggaaccgag aaaaaccatt tatgccccac cagccgataa
    66301 gagccatctt ccagacgctc tgcacgggtg gtgttgctca taacatcgga accgccctgc
    66361 ttttccgtca ttcccatgcc aatcaacaaa ccgcgttttt gcccacctgg caataagtga
    66421 gaatcgtagc gatcgctcaa tagcggcgtg gtccagtcct gaaacggcgc gggtaacatc
    66481 tgtaacaaca atggcgtggc ggcaaaggtc atggttatcg gacataacga ccctgcctca
    66541 acctgcgcat gtaacataaa acgcgccgcg cgcgccacaa atgcgccgga gcgagcgtct
    66601 tcttcccagg caagattgtg cacccgattg gtacatagcg cctgcatcag caggtgccag
    66661 gcggggtgaa aacgcacatc gtccagacgg cgtccttgcg catcgtagcg caataattca
    66721 ggcggattca cattcgccag ccgccccagt tcaagggatt cagccgttcc taactgctga
    66781 ccaatactgg ctagaaaatc gctatcccag ccagcacctt cacgcgttac cgcttcgcag
    66841 agcgcgccat cagacaggta taagttgctg ttatttaatg gtataggttg attaaaaacg
    66901 gtgtgagttt gccagtgcac tgtgtctccc tccatcaatg gcagtcacca ttagtatggt
    66961 cactgccatg gattcatgac agaaagagat tgctaaaaca ttcttatcca gcaatgtaat
    67021 gcggaacgaa acgtgaggtg tctttggtga tcagtgtgtt atcttcacgg atccccattc
    67081 cgcacgcttc atcatcgaca atccagctac cgatgagtgt gtagctatcg ccaaaccgcg
    67141 gcagaggttg aaacgcctgg tagatcatcg gttcatcggc gtaatcacca tcagcgtggt
    67201 caacgacgtt attctggccg tcgaaaatgg tgacatttcc gccttcgcgc gagtagagcg
    67261 gtttacgcac atagctttcg ccagcggcaa tctgcgattt ttcaccctca aaccaggatg
    67321 caagaaggtt aggatgacca gggaagaagc gccaaagcag cggcattagc cctttattac
    67381 tcaagatact tttccataac ggctccaccc attgctcgcg acgcttgcgc agcagcggac
    67441 cgttatcgtc acgcatcatc ccctccagcg gatacagctt aaatgcacgc tggatgacat
    67501 tatcatcaag atcggtcagt acgccgccga cgcccaaacc gagatcttca atgtagataa
    67561 accgcgactc ctgccctgcc tgctgggcgc agtcctgcaa gtacagcacg gtactcctgt
    67621 cttcatcggt gtcctgacag cagcaaaaat aaaacggttc ccgactgtaa agctcgctaa
    67681 agcgtgaaat caggcgttcc tgaatagcat tgtactgatc ggcatcacgc ggaataatgc
    67741 cgctgcgccg ggcatcctcc agccacagcc actggaaata agccgactcg tacaatgaag
    67801 ttggcgtatc ggcgttgtac tccagcagct tcaccggcgc attgccacac caggcaaaat
    67861 ccatccgtcc atacagcgaa ggatcgcggg cgcgccagct ttcagcgatc acatcccagt
    67921 acaacggcgg gatcgccagt tgcgtcagga tctcttcatc ttttaccgcg cgatccacca
    67981 cctcaaggca catctgatgc agttccgcag tcggtttttc gatctgctct tcaatctggc
    68041 gcagagtaaa acggtaagcc cgactctcat cccaatagat ttcattgtcg atgatatgaa
    68101 agtcgaaacc gttgtcagcg gcgatctggt ccagatcccg tcgcacagga acgttgtgtc
    68161 tcagcatgat tagcctcccc aatgcccacg ggcgctggaa gaacgaccat agccgccgcg
    68221 agaaacggta gacgcttttt tggtggtaaa gccgcccgaa gagtaagact cttttttgcc
    68281 agaaccggag cgccaagagt aatcaccaga agtgctgcgc cagactgggc gcgaagcaaa
    68341 agaggaaccg ccgctgttat aaacaaacgg ctcatcgcga tctttacgaa taacccggct
    68401 taacaaaaat ccagaaacga ccgggatcca actctgttca acattgtcgt agtagcaatt
    68461 ttcgtactta gactgacagt tctgctgagt catattcttc ggaacatcgg cataaaatgc
    68521 cgttttggcg ttgttccagc cacgcgcgca aatgtcggca ttattaccgt catcaataca
    68581 atcctgcact gtcgcgtaaa acgttccgtc gccgtcgtta tcgacatcgc tactatcgct
    68641 acaacctttc aatacgaaaa aagcggcacc gcccattagc gccaacgtta agtatttttg
    68701 tgcgtagcga ttgcgacgcg gttcaaaagg attattcggt ctaccaatgc gactaatcgc
    68761 tccgtgacca attttactgt tatttcttga tttgcgtttt ctggccatga tcgtccatta
    68821 ccatgtcata caagctgcgt taaaaatacc gccagccagc gcggcggttc ccataaacat
    68881 tcctgctgcg gtattgtgat taataatttt ttcgcttaat gcgggcatat aaagtctgac
    68941 accagcaaaa acgagtaact gaatcaccag tgcaatcccg ccccaggcga aatagtctgg
    69001 aatactcacc gcattgattg ccgcactgga taaggggata acgtaaccca acaatgtacc
    69061 gctgaacgcc agtgacgccg cggtattatt gtttttgatt aactgccatt cgttgtgcgg
    69121 tgtaatttta gaatagataa atagaaaaat aatcaccata gccacgccaa taaaaaaata
    69181 ggcgctaaag gcaagaagtg aatccagtat atgcattgta aacgtccttg taattaacca
    69241 ataatatgaa gtgatgtcag cgggatatcg acacccaacg cgcgcgaaaa taaccactct
    69301 ggctcgccga gatcgttaaa agattcctca ccatttagca gcaaatattc gtaagtatct
    69361 tcggttactt gccgttggta gcccatggta aaattatgga cctcccattt ggcatggttt
    69421 tgattttcta ctttttccag catgtagacg ggttcgatat ttcccggttc ttcgctgtta
    69481 aaaaatcgct gccagcgttt ttcctgccag tttaaggtca ttgctcccat cgctttggcg
    69541 ttgatcgcct cgcgccagtg actctcttta ctgataccgt agctctcttc atagacaaag
    69601 agcttgatat catcaatgtc atcaatatct tcgccgccgg tggtattgat ttgcagaaac
    69661 tcatcgcctg aagtgtagta gcggaaaatc tgactaccgc cgcccagatc gatgtggctg
    69721 acggcggcta ccgtaaattc ctcacccggc agcgcaatca gcaattcatc ttccagcaaa
    69781 cgaaacgcta acgtgtcgag cgtaaagcca ctattgagat gaagtcccag cggaccacga
    69841 gcgatagctg gcttattatc cttgccaaac agacgctgga aaaaaccaga catattttat
    69901 ccttaaaata gttgccagcc ttttagcgag gctggcaaaa aaattactcg ccctgttggc
    69961 gttgcagtct tgctaataca tcctgggcgc tacttttatt gctaccgcca attccggctt
    70021 ccgccagctt ttcgtcaagg tcgcgaccgt ctgcgacttt ctccaactgt gcggcagcat
    70081 ccaggcgagc ctgacgttcg gcctgacgcg tttgcaggcg ttttaaggat tctgccgctg
    70141 tcgaaacgct ggaagatgcg ccaacggtag aggttgttac agcctgttgt gcacgctgca
    70201 tggcttcagt ggctttaacg acttccattt gctgctcaaa ctgagcgata cgctgcgctg
    70261 tcgctgtaac tgctttttcc acgccatcac gggagacttc cagattcgac aacacttgct
    70321 cttcagcggt aatgagattc tcaaggcgcg cgatttcttc agcaacttcg ttaatcaacg
    70381 acggattaac gttcttgctt aacgcttcca gcgcacgggc ttccagactg gctttgcgct
    70441 cacgtaaatc tttcagctta tcgtgactta atttcacccg cgccagcaga tcaacgcgag
    70501 attttccggc tttatcgagt tcagctttag cgtcacgaat atgctgttcc agcatgcgca
    70561 cgccctgggt ttcttcaatg gattcttccg cctgggagat aaacgatttc cccagcgtaa
    70621 ataaactttt taaaattccc ataaataccc gtccttgtaa ttagtgtgaa tattcttctg
    70681 taatttcagc cagatccaat gcgttatcta ccagcgaggt tatctcaagc aggatatctt
    70741 caagagaaga tttaagcgat aacgccccga aaacaatgta atactcttcc tgttgtacgc
    70801 tggagatccc taccgatgac aacggcatca tcttctgatt tcttaataag aaggtattaa
    70861 attcatctgg attgctgata ctactcaccg gacaaataaa ggtttcgata atcatttggc
    70921 gggaagtaaa aagaatattg atttgcaaat cgccataatc attcatttta ataattaatg
    70981 cgttctcgct atttgttaca tcaatatttt gttcaggtac agtttgcagc gccgt
//
LOCUS       DAPHKZ010000009        69456 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.009, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000009 DAPHKZ010000000
VERSION     DAPHKZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 69456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69456
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.009"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..771
                     /gene="htrE"
                     /locus_tag="RH288_000602"
     CDS             <1..771
                     /gene="htrE"
                     /locus_tag="RH288_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Yad fimbria usher protein HtrE"
                     /protein_id="HDV4029699.1"
                     /translation="NQLNVSSSGYSDNARVSYSVNTGYTMNKASKDLSYVGGYASYES
                     PWGTLAGSISANSDNSRQVSLSTDGGFVLHSGGLTFSNDSFSDSDTLAVVQAPGAQGA
                     RINYGNSTIDRWGYGVTSALSPYHENRIALDINDLENDVELKSTSAVAVPRQGSVVFA
                     DFETVQGQSAIMNITRSDGKNIPFAADIYDEQGNVIGNVGQGGQAFVRGIEQQGNISI
                     KWLEQSKPVSCLAHYQQSPEAEKIAQSIILNGIRCQIQ"
     gene            788..1357
                     /locus_tag="RH288_000603"
     CDS             788..1357
                     /locus_tag="RH288_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414680.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4029700.1"
                     /translation="MIKTTPHKIVILMGILLSPSVFATDINVEFTATVKATTCNITLT
                     GNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNAS
                     SSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLE
                     MTVALRETDAGQGVPGNFRALATFNFIYQ"
     gene            1369..1974
                     /gene="yadL"
                     /locus_tag="RH288_000604"
     CDS             1369..1974
                     /gene="yadL"
                     /locus_tag="RH288_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein YadL"
                     /protein_id="HDV4029701.1"
                     /translation="MMTFKNLRYGLSSSVVLAASLFSVLSYAATDSIGLTVITTVEMG
                     TCTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKR
                     ATCEGTANDGAGFANGSTAADKASAVAVEVWSTVTPATGSATQFSCVTPASQEVTIST
                     AANAVVYYPMSARLVVEKNKTVNNVTAGKFSAPATFTVTYN"
     gene            2001..2597
                     /locus_tag="RH288_000605"
     CDS             2001..2597
                     /locus_tag="RH288_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4029702.1"
                     /translation="MHPTQRKLMKRIILFLSLLFCIACPAIAGQDIDLVANVKNSTCK
                     SGISNQGNIDLGVVGVGYFSGNVTPESYQPGGKEFTITVSDCALQGTGDVLNQLHIDF
                     RALSGVMAAGSRQIFANEISSGASNVGVVIFSTQDSANTFNVLNASGGSRSVYPVMSD
                     DMNGSSWKFSTRMQKIDPALSVTSGQLMSHVLVDIYYE"
     gene            2647..3885
                     /gene="yadC"
                     /locus_tag="RH288_000606"
     CDS             2647..3885
                     /gene="yadC"
                     /locus_tag="RH288_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial tip-adhesin YadC"
                     /protein_id="HDV4029703.1"
                     /translation="MKTIFRYILFLALYSCCNTVSAYTSFIVGNNAGVDNYRGPSTAA
                     QMTFNYTSTASNLVFYKPTQLGPTGVKMYWSYLDTGTGGGILYCNTSGRANPGPITIE
                     NAMVYSGKDYGGHKLFNTSVPGLYYTMLISRVWSAYDTITDIQSPGIYIGDPSNQEFF
                     FSVTDSDLQTKGCNKADDYDKFWAIGGIVHNITVEFYTDTNFDPTLNQQVQLSSSSNY
                     LYSFKAYSPGTKVVDHSNHIYVNFTLNNVKLTLPTCFTSILTGPSVNGSTVRMGEYSS
                     GTIKNGASPVPFDISLQNCIRVRNIETKLVTGKVGTQNTQLLGNTLTGSTAAKGVGVL
                     IEGLATSKNPLMTLKPNDTNSVYIDYETEDDTSDGVYPNQGNGTSQPLHFQATLKQDG
                     NIAIEPGEFKATSTFQVTYP"
     gene            3999..4793
                     /gene="panB"
                     /locus_tag="RH288_000607"
     CDS             3999..4793
                     /gene="panB"
                     /locus_tag="RH288_000607"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDV4029704.1"
                     /translation="MKPTTISLLQKYKQEKKRFATITAYDYSFAKLFADEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
                     DQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     gene            4805..5656
                     /gene="panC"
                     /locus_tag="RH288_000608"
     CDS             4805..5656
                     /gene="panC"
                     /locus_tag="RH288_000608"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDV4029705.1"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLID
                     NKMVELA"
     gene            complement(5714..6625)
                     /gene="rpnC"
                     /locus_tag="RH288_000609"
     CDS             complement(5714..6625)
                     /gene="rpnC"
                     /locus_tag="RH288_000609"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnC"
                     /protein_id="HDV4029706.1"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEEKGIEKGIQQGRQEVSQEFAQRLLSKG
                     MSREDVAEMANLPLAEIDKVINKLPVL"
     gene            6899..7279
                     /gene="panD"
                     /locus_tag="RH288_000610"
     CDS             6899..7279
                     /gene="panD"
                     /locus_tag="RH288_000610"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HDV4029707.1"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(7283..8512)
                     /locus_tag="RH288_000611"
     CDS             complement(7283..8512)
                     /locus_tag="RH288_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDV4029708.1"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYAFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLVTWKDTPVYNAPSAGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLSVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMVQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRVDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVWYLSYPFGGFNDNAVKAANDAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     gene            complement(8576..9016)
                     /locus_tag="RH288_000612"
     CDS             complement(8576..9016)
                     /locus_tag="RH288_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDV4029709.1"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSEFRERIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
     gene            complement(9121..9891)
                     /locus_tag="RH288_000613"
     CDS             complement(9121..9891)
                     /locus_tag="RH288_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4029710.1"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     gene            complement(9888..10814)
                     /locus_tag="RH288_000614"
     CDS             complement(9888..10814)
                     /locus_tag="RH288_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4029711.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRA"
     gene            10923..11585
                     /gene="can"
                     /locus_tag="RH288_000615"
     CDS             10923..11585
                     /gene="can"
                     /locus_tag="RH288_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HDV4029712.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     gene            complement(11626..12162)
                     /gene="hpt"
                     /locus_tag="RH288_000616"
     CDS             complement(11626..12162)
                     /gene="hpt"
                     /locus_tag="RH288_000616"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDV4029713.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     gene            12368..14758
                     /gene="gcd"
                     /locus_tag="RH288_000617"
     CDS             12368..14758
                     /gene="gcd"
                     /locus_tag="RH288_000617"
                     /EC_number="1.1.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein glucose dehydrogenase"
                     /protein_id="HDV4029714.1"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     gene            complement(14960..16510)
                     /gene="cueO"
                     /locus_tag="RH288_000618"
     CDS             complement(14960..16510)
                     /gene="cueO"
                     /locus_tag="RH288_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HDV4029715.1"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     gene            16676..17023
                     /locus_tag="RH288_000619"
     CDS             16676..17023
                     /locus_tag="RH288_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HDV4029716.1"
                     /translation="MKTFFRTVLFGILMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            17129..17995
                     /gene="speE"
                     /locus_tag="RH288_000620"
     CDS             17129..17995
                     /gene="speE"
                     /locus_tag="RH288_000620"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDV4029717.1"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALP
                     QYLQDALASQPS"
     gene            18011..18805
                     /gene="speD"
                     /locus_tag="RH288_000621"
     CDS             18011..18805
                     /gene="speD"
                     /locus_tag="RH288_000621"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDV4029718.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     gene            complement(18843..19205)
                     /locus_tag="RH288_000622"
     CDS             complement(18843..19205)
                     /locus_tag="RH288_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414661.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HDV4029719.1"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     gene            complement(19381..21978)
                     /gene="acnB"
                     /locus_tag="RH288_000623"
     CDS             complement(19381..21978)
                     /gene="acnB"
                     /locus_tag="RH288_000623"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HDV4029720.1"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREVLGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKA
                     DGVIFQTAV"
     gene            22333..24186
                     /locus_tag="RH288_000624"
     CDS             22333..24186
                     /locus_tag="RH288_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HDV4029721.1"
                     /translation="MKMTLPFKPHVLALICSAGLCAASTGLYIKSRTVEAPVEPQSTQ
                     LAVSDAAAVTFPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDALLSQVLMASTY
                     PTNVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKVITTTKKAVPVKQTVTAPVIPSN
                     TVLTANPVITEPATTVISIEPANPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDNDDYHHHDGGHRDGNGWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVPYHDQDMAKRFHQTNVNGGMSA
                     TQLPAPTRDSQRQAAANQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGSYDDFHDFS
                     RRQPLTQQQKDAARQRYQSASPEQRQAVRERMQTNPKIQQRREAARERIQSASPEQRQ
                     AVREKMQTNPQNQQRRDAARERIQSASPEQRQVFKEKVQQRPLNQQQRDNARQRVQSA
                     SPEQRQVFREKVQESRPQRLNDSNHTVRLNNEQRSAVRERLSERGARRLER"
     gene            complement(24257..25681)
                     /gene="lpdA"
                     /locus_tag="RH288_000625"
     CDS             complement(24257..25681)
                     /gene="lpdA"
                     /locus_tag="RH288_000625"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDV4029722.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     gene            complement(26006..27898)
                     /gene="aceF"
                     /locus_tag="RH288_000626"
     CDS             complement(26006..27898)
                     /gene="aceF"
                     /locus_tag="RH288_000626"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDV4029723.1"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     gene            complement(27913..30576)
                     /gene="aceE"
                     /locus_tag="RH288_000627"
     CDS             complement(27913..30576)
                     /gene="aceE"
                     /locus_tag="RH288_000627"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HDV4029724.1"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     gene            complement(30737..31501)
                     /gene="pdhR"
                     /locus_tag="RH288_000628"
     CDS             complement(30737..31501)
                     /gene="pdhR"
                     /locus_tag="RH288_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HDV4029725.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     gene            32042..33415
                     /gene="aroP"
                     /locus_tag="RH288_000629"
     CDS             32042..33415
                     /gene="aroP"
                     /locus_tag="RH288_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HDV4029726.1"
                     /translation="MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIK
                     VIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPV
                     NTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQG
                     VVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKT
                     AKAVKAH"
     gene            complement(33458..34312)
                     /gene="ampE"
                     /locus_tag="RH288_000630"
     CDS             complement(33458..34312)
                     /gene="ampE"
                     /locus_tag="RH288_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HDV4029727.1"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     GMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     gene            complement(34309..34860)
                     /gene="ampD"
                     /locus_tag="RH288_000631"
     CDS             complement(34309..34860)
                     /gene="ampD"
                     /locus_tag="RH288_000631"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HDV4029728.1"
                     /translation="MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIAKNMTGHCDIAPD
                     RKTDPGPAFDWARFRVLVSKETT"
     gene            34948..35841
                     /gene="nadC"
                     /locus_tag="RH288_000632"
     CDS             34948..35841
                     /gene="nadC"
                     /locus_tag="RH288_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDV4029729.1"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     SLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     gene            36044..36484
                     /gene="ppdD"
                     /locus_tag="RH288_000633"
     CDS             36044..36484
                     /gene="ppdD"
                     /locus_tag="RH288_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HDV4029730.1"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
     gene            36494..37879
                     /gene="gspE"
                     /locus_tag="RH288_000634"
     CDS             36494..37879
                     /gene="gspE"
                     /locus_tag="RH288_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
                     /protein_id="HDV4029731.1"
                     /translation="MNIPQLTALCLRYHGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLPCRGGEKVVLRLLQQVGQALDVNTLGMQPLQLADFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQKLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     gene            37869..39071
                     /gene="hofC"
                     /locus_tag="RH288_000635"
     CDS             37869..39071
                     /gene="hofC"
                     /locus_tag="RH288_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HDV4029732.1"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRTLLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWSW
                     LLVLFGFLLAIANKLLMRRPTWLIVRQKLLLRIPIMGSLMRGQKLTQIFTILALTQSA
                     GITFLQGVESVRETMRCPYWVQLLTQIQHDISNGQPIWLALKNTGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRENTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(39106..40149)
                     /gene="guaC"
                     /locus_tag="RH288_000636"
     CDS             complement(39106..40149)
                     /gene="guaC"
                     /locus_tag="RH288_000636"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDV4029733.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     gene            complement(40305..40349)
                     /locus_tag="RH288_000637"
     CDS             complement(40305..40349)
                     /locus_tag="RH288_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029734.1"
                     /translation="MIIKTLKMSARKRN"
     gene            40374..40994
                     /gene="coaE"
                     /locus_tag="RH288_000638"
     CDS             40374..40994
                     /gene="coaE"
                     /locus_tag="RH288_000638"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDV4029735.1"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     gene            40994..41737
                     /gene="zapD"
                     /locus_tag="RH288_000639"
     CDS             40994..41737
                     /gene="zapD"
                     /locus_tag="RH288_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HDV4029736.1"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDTENGQVPERLDFELACC"
     gene            41747..41944
                     /gene="yacG"
                     /locus_tag="RH288_000640"
     CDS             41747..41944
                     /gene="yacG"
                     /locus_tag="RH288_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HDV4029737.1"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     gene            complement(42160..42549)
                     /gene="mutT"
                     /locus_tag="RH288_000641"
     CDS             complement(42160..42549)
                     /gene="mutT"
                     /locus_tag="RH288_000641"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HDV4029738.1"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVERWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRL"
     gene            complement(42609..45314)
                     /gene="secA"
                     /locus_tag="RH288_000642"
     CDS             complement(42609..45314)
                     /gene="secA"
                     /locus_tag="RH288_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDV4029739.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     gene            complement(45376..45888)
                     /gene="secM"
                     /locus_tag="RH288_000643"
     CDS             complement(45376..45888)
                     /gene="secM"
                     /locus_tag="RH288_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HDV4029740.1"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPKTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLT"
     gene            complement(46119..47036)
                     /gene="lpxC"
                     /locus_tag="RH288_000644"
     CDS             complement(46119..47036)
                     /gene="lpxC"
                     /locus_tag="RH288_000644"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HDV4029741.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     gene            complement(47137..48288)
                     /gene="ftsZ"
                     /locus_tag="RH288_000645"
     CDS             complement(47137..48288)
                     /gene="ftsZ"
                     /locus_tag="RH288_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDV4029742.1"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     gene            complement(48349..49611)
                     /gene="ftsA"
                     /locus_tag="RH288_000646"
     CDS             complement(48349..49611)
                     /gene="ftsA"
                     /locus_tag="RH288_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDV4029743.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            complement(49608..50438)
                     /gene="ftsQ"
                     /locus_tag="RH288_000647"
     CDS             complement(49608..50438)
                     /gene="ftsQ"
                     /locus_tag="RH288_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HDV4029744.1"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPERTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     gene            complement(50440..51360)
                     /gene="ddlB"
                     /locus_tag="RH288_000648"
     CDS             complement(50440..51360)
                     /gene="ddlB"
                     /locus_tag="RH288_000648"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDV4029745.1"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            complement(51353..52828)
                     /gene="murC"
                     /locus_tag="RH288_000649"
     CDS             complement(51353..52828)
                     /gene="murC"
                     /locus_tag="RH288_000649"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDV4029746.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPARVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     gene            complement(52882..53949)
                     /gene="murG"
                     /locus_tag="RH288_000650"
     CDS             complement(52882..53949)
                     /gene="murG"
                     /locus_tag="RH288_000650"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDV4029747.1"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRVARA"
     gene            complement(53946..55190)
                     /gene="ftsW"
                     /locus_tag="RH288_000651"
     CDS             complement(53946..55190)
                     /gene="ftsW"
                     /locus_tag="RH288_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HDV4029748.1"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     gene            complement(55190..56506)
                     /gene="murD"
                     /locus_tag="RH288_000652"
     CDS             complement(55190..56506)
                     /gene="murD"
                     /locus_tag="RH288_000652"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDV4029749.1"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     gene            complement(56509..57591)
                     /gene="mraY"
                     /locus_tag="RH288_000653"
     CDS             complement(56509..57591)
                     /gene="mraY"
                     /locus_tag="RH288_000653"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDV4029750.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            complement(57585..58943)
                     /gene="murF"
                     /locus_tag="RH288_000654"
     CDS             complement(57585..58943)
                     /gene="murF"
                     /locus_tag="RH288_000654"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDV4029751.1"
                     /translation="MISVTLSQLTDILNGDLQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGK
                     QSHAISTASGVGEHFADKTALITRLKLLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     gene            complement(58940..60427)
                     /gene="murE"
                     /locus_tag="RH288_000655"
     CDS             complement(58940..60427)
                     /gene="murE"
                     /locus_tag="RH288_000655"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDV4029752.1"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     IDVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     gene            complement(60414..62180)
                     /gene="ftsI"
                     /locus_tag="RH288_000656"
     CDS             complement(60414..62180)
                     /gene="ftsI"
                     /locus_tag="RH288_000656"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HDV4029753.1"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTVPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     gene            complement(62196..62561)
                     /gene="ftsL"
                     /locus_tag="RH288_000657"
     CDS             complement(62196..62561)
                     /gene="ftsL"
                     /locus_tag="RH288_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDV4029754.1"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            complement(62558..63499)
                     /gene="rsmH"
                     /locus_tag="RH288_000658"
     CDS             complement(62558..63499)
                     /gene="rsmH"
                     /locus_tag="RH288_000658"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDV4029755.1"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     gene            complement(63501..63959)
                     /gene="mraZ"
                     /locus_tag="RH288_000659"
     CDS             complement(63501..63959)
                     /gene="mraZ"
                     /locus_tag="RH288_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDV4029756.1"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIYHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     gene            complement(64561..65565)
                     /gene="cra"
                     /locus_tag="RH288_000660"
     CDS             complement(64561..65565)
                     /gene="cra"
                     /locus_tag="RH288_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HDV4029757.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     gene            complement(65647..65733)
                     /locus_tag="RH288_000661"
     CDS             complement(65647..65733)
                     /locus_tag="RH288_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fruR/shl operon leader peptide"
                     /protein_id="HDV4029758.1"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            complement(65745..66236)
                     /gene="ilvN"
                     /locus_tag="RH288_000662"
     CDS             complement(65745..66236)
                     /gene="ilvN"
                     /locus_tag="RH288_000662"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HDV4029759.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSGKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     gene            complement(66239..67963)
                     /gene="ilvI"
                     /locus_tag="RH288_000663"
     CDS             complement(66239..67963)
                     /gene="ilvI"
                     /locus_tag="RH288_000663"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HDV4029760.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQIFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHQQLKETVEALNLPVVCSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPHELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            68082..68126
                     /locus_tag="RH288_000664"
     CDS             68082..68126
                     /locus_tag="RH288_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029761.1"
                     /translation="MKRNDKILHYRGLN"
     gene            complement(68281..69225)
                     /gene="leuO"
                     /locus_tag="RH288_000665"
     CDS             complement(68281..69225)
                     /gene="leuO"
                     /locus_tag="RH288_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HDV4029762.1"
                     /translation="MPEVQTDHSETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     VLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
BASE COUNT        16992 a        18906 c        16883 g        16675 t
ORIGIN      
        1 aaccaactca acgttagcag cagtggctat agcgataacg ctcgcgtcag ttatagcgtg
       61 aatactggct atacgatgaa taaagccagc aaagatttga gttatgttgg gggttatgcc
      121 agctatgagt caccatgggg aacgctggca ggttcaattt ctgcaaatag cgataacagc
      181 cgtcaagttt ctctcagcac cgacggtggt tttgtattgc atagcggtgg actgactttc
      241 agtaatgata gttttagcga ctccgataca ctggcggtag ttcaggctcc aggtgctcaa
      301 ggagcgcgaa taaattatgg caacagtact atcgatcgat ggggttatgg tgtcaccagc
      361 gctctttctc cttatcatga aaaccgtatc gcgctggata tcaacgatct tgagaacgat
      421 gttgaattaa aaagtaccag tgcagtagct gtaccgcgtc agggttcagt cgtctttgct
      481 gattttgaaa ccgtgcaagg gcaatcagcc attatgaaca tcacacgaag tgatggtaaa
      541 aatattccat ttgctgcaga tatttatgat gagcaaggca atgtcattgg taatgttgga
      601 cagggtggac aagcatttgt tcgtggtatt gagcagcagg gaaatatcag cattaaatgg
      661 ctcgaacaaa gtaaacccgt aagttgtctt gcgcattatc aacaaagccc agaagcagaa
      721 aaaatagcac aatctattat tctgaatgga attcggtgtc agattcagta actacaaggg
      781 acgtcaaatg ataaaaacaa cgccacataa aatagtgata ctgatgggaa tattattatc
      841 accctcagta tttgcaacgg atattaatgt agagtttaca gccactgtca aagcgacaac
      901 ctgtaacatc acacttactg gtaataacgt cacgaatgat ggcaataata actacacatt
      961 gagaatccct aagatgggtc tggataagat cgcgaataaa acgacagaat ctcaggctga
     1021 ttttaaactg gttgccagtg ggtgcagcag tggcatcagt tggattgata ccactctgac
     1081 cggaaatgca tcatcaagct cacctaagct tattataccg cagtctggtg attcatcttc
     1141 gacgacaagt aatatcggta tgggtttcaa aaaacggact actgatgatg ccactttcct
     1201 taaacctaac agtgcggaaa agatacgctg gagcacagac gagatgcagc ccgataaggg
     1261 tcttgaaatg accgttgcgc tacgtgaaac agatgcaggg caaggcgtac cggggaattt
     1321 tcgtgcactg gcgacgttta atttcatcta tcaataagaa ggataattat gatgacattt
     1381 aaaaatttac gttatggatt atccagcagt gtcgttttgg ctgcctcatt gttcagtgta
     1441 ctctcttatg cggcaacaga cagtattgga ctgaccgtta ttactactgt agaaatgggt
     1501 acttgtaccg ctacattagt aaatgactct gatcaggaca tttctgttgt tgattttggt
     1561 gatgtatata tttctgaaat caatgccaag accaaagtaa aaacattcaa actcaaattc
     1621 aaagactgtg cgggtatccc caataaaaaa gcgcaaataa aattaaccaa gcgagccaca
     1681 tgcgagggaa ctgctaatga cggtgcgggg tttgcaaatg gttccacagc cgcagataaa
     1741 gcaagtgctg tcgccgttga agtctggagc actgtaactc cggcaacagg gagtgcaaca
     1801 caatttagct gtgtaacacc agcatcacaa gaggtaacaa tctccactgc agccaatgcg
     1861 gtcgtttatt atccgatgag tgcacgcctg gtcgtggaaa aaaataaaac cgtaaacaat
     1921 gtcactgcgg gtaagttttc tgcaccagcc acatttacag taacctataa ctaacagact
     1981 tacagattca ggaactatat atgcatccca ctcaacgtaa gctgatgaag agaataattc
     2041 tgtttctgtc attactgttt tgcatcgcct gtccagccat tgctggacag gatattgacc
     2101 ttgttgccaa tgtaaaaaac agcacctgca aaagcggaat cagtaaccag ggtaatattg
     2161 atcttggcgt cgttggggtg ggatattttt caggtaatgt tactcctgaa agttatcaac
     2221 caggtggaaa agagttcact atcactgtat ccgactgtgc attacaggga actggcgatg
     2281 tgctaaatca gttacatatt gattttagag cccttagcgg tgtcatggct gctggctcta
     2341 ggcaaatatt tgctaatgaa atttcgtcag gagcaagtaa tgtaggagta gttatatttt
     2401 ctactcagga ttcggcgaat acattcaatg ttcttaatgc ttcaggcgga tctcgttccg
     2461 tttatccagt aatgtcggat gacatgaatg gttcatcctg gaaatttagc acccgaatgc
     2521 aaaaaatcga tcctgcattg agtgttacat ctggtcaact tatgagccat gtgttagtgg
     2581 atatttacta cgaataacaa acaaaaacag cgcaaaccat aacaataaag aaacattgga
     2641 gtaaaaatga agactatctt caggtacatt ctttttttag cactgtattc ttgttgtaat
     2701 acagtcagtg catatacaag ttttattgtg ggaaataatg caggagttga taactatcga
     2761 ggcccctcca ctgccgcaca gatgaccttt aattacacat caacagcaag caacttggtt
     2821 ttttataaac ccacgcagct cggcccgact ggggtaaaaa tgtactggtc atacctggat
     2881 acaggtaccg gtggtggtat tctttactgc aatacatctg gcagagcgaa tcctggtcca
     2941 ataactattg aaaatgccat ggtctattca ggtaaagatt atggcggaca taaactattt
     3001 aatacatctg ttcctggtct gtattacacc atgttaatat caagggtctg gtctgcatac
     3061 gatacaataa ctgacattca atcgccagga atctatatcg gagatccttc caaccaagaa
     3121 tttttctttt ccgtcacaga cagcgatcta caaactaagg gttgcaacaa agcagacgac
     3181 tacgataagt tttgggctat tggtggtata gtacacaaca taactgttga attttataca
     3241 gatactaatt tcgatcctac acttaatcag caagtccagt tatccagttc atcaaattac
     3301 ctttattcgt ttaaggccta cagtcctggt acaaaagttg tagatcacag caaccacatt
     3361 tatgtcaatt tcacactgaa taatgtcaaa ttaaccttac caacatgttt tacctccata
     3421 cttaccgggc catcagtcaa tggttcaacg gttagaatgg gagaatatag ctctgggaca
     3481 attaaaaatg gcgcttcacc tgttcccttt gatatctcgc ttcagaattg tattcgtgtg
     3541 cgtaatattg aaacaaaact cgtcactgga aaagtaggta ctcaaaacac acaactgctt
     3601 ggtaatacgc ttactggaag cactgccgcc aaaggcgttg gcgtactcat tgaaggttta
     3661 gcaaccagta aaaatccgct aatgacatta aaacctaatg atacgaattc tgtttatata
     3721 gattatgaaa ccgaagatga cacctccgat ggggtttacc ctaatcaagg taacggcaca
     3781 tcacagcctc ttcatttcca ggcaacatta aagcaagacg ggaatattgc tatcgaaccc
     3841 ggcgaattta aagccaccag tactttccag gtaacctatc cctgataacg tagcagcact
     3901 gtcaccttct ggcagtgctg ctacggataa atcattgccc ccaccaatgt gactgataaa
     3961 atgccagaca gcacaacatc aatttatcag gatacgttat gaaaccgacc accatctcct
     4021 tactgcagaa gtacaaacag gaaaaaaaac gtttcgcgac catcaccgct tatgactata
     4081 gcttcgccaa actctttgct gatgaagggc ttaacgtcat gctggtgggc gattcgctgg
     4141 gcatgacggt tcaggggcac gactccaccc tgccagttac cgttgccgat atcgcctacc
     4201 acactgccgc cgtacgtcgc ggcgcaccaa actgcctgct gctggctgac ctgccgttta
     4261 tggcgtatgc cacgccggaa caagccttcg aaaacgccgc aacggttatg cgtgccggtg
     4321 ctaacatggt caaaattgaa ggcggtgagt ggctggtaga aaccgtacaa atgctgaccg
     4381 aacgtgccgt tcctgtatgt ggtcacttag gtttaacacc acagtcagtg aatattttcg
     4441 gtggctacaa agttcagggg cgcggcgatg aagcgggcga tcaactgctc agcgatgcat
     4501 tagccttaga agctgctggg gcacagctgc tggtgctgga atgcgtgccg gttgaactgg
     4561 caaaacgtat taccgaagca ctggcgatcc cggttattgg cattggcgca ggcaacgtca
     4621 ctgacgggca gatcctcgtg atgcacgacg cctttggtat taccggcggt cacattccta
     4681 aattcgctaa aaatttcctc gccgaaacgg gcgacatccg cgcggctgtg cggcagtata
     4741 tggctgaagt ggagtccggc gtttatccgg gcgaagaaca cagtttccat taaggagtca
     4801 cgttgtgtta attatcgaaa ccctgccgct gctgcgtcag caaattcgcc gcctgcgtat
     4861 ggaaggcaag cgcgtggcgc tggtgcctac catgggtaac ctgcacgatg gccatatgaa
     4921 gctggtcgac gaagccaaag cccgcgccga tgtggtcgtc gtcagtattt tcgttaaccc
     4981 gatgcagttc gaccgcccgg aagatctggc tcgttatcca cggaccttgc aggaggactg
     5041 cgagaagcta aacaaacgta aagtggattt agttttcgcc ccttcggtaa aagagatcta
     5101 cccgaacggt actgaaaccc acacttacgt tgacgttcct ggcctttcga ccatgctgga
     5161 aggtgccagc cgtccgggac attttcgcgg cgtttcgact attgtcagca agctgttcaa
     5221 cctggtccag ccggacatcg cctgcttcgg tgaaaaagat tttcagcaac tggcgctgat
     5281 ccgcaaaatg gttgccgata tgggcttcga tattgagatt gtcggtgtgc caattatgcg
     5341 cgccaaagac ggtctggcgc taagttcccg taacggttat ctgacggcgg aacaacgcaa
     5401 aattgcgcct ggtctgtaca aagttttaag ttcgattgct gacaaattgc aggctgggga
     5461 acgggatctc gatgaaatta ttaccattgc ggggcaagaa ctgaatgaaa aaggcttccg
     5521 cgccgatgat attcagattc gtgatgccga cacattgctg gaagtttctg aaaccagcaa
     5581 acgggcagta attctggtag ccgcctggct tggcgatgct cgcctgatcg acaacaaaat
     5641 ggtcgagctg gcgtaatact taactggcgc tacggctgat ggcgccagtt attaatttac
     5701 cccacgtcat ctgtcataac acaggtaact tattaattac cttatcaatc tcagcaagag
     5761 gtaaatttgc catctctgca acgtcttccc gagacattcc tttactcaga agacgctggg
     5821 cgaattcctg acttacttcc tgtcttccct gctgaatccc cttctcaatc cctttctctt
     5881 caaaccactg cgccagcgtc atcatagact cccctcccgt ttccctgtct ctcaacacac
     5941 cgtaaaacaa atccgcttgt tcagtatgac cgcgttgcag catatagttt tgcatggcaa
     6001 ctaactgact tccgctagtg tacccttcgt cgatcagcgt gaccagttgc tcaagcaata
     6061 acattaagtc gcgctggcga atatgttttt gcagtaattc gagaatcgca atccgccgat
     6121 gttgcatgat ttcgtcatcc ggtgtgatgg tgatatccac cagcgggaaa ggactgttat
     6181 agacgcgtcg cgccagctcc ggcgagtaaa acatatcaaa ccagcacatt gatagcggat
     6241 aaggtgtggc ctcgccctga taaaacagta tcggcaccac cagcggcagc ttatcgtggt
     6301 cagcctccag atgccggtgc atggcggcta tagaataacg catcatgcga aaggccattt
     6361 tcttatccgg cttgctttgg tgttcaatca caacatgcag ataaccggga ttgccctgca
     6421 tttgcacgga atagagcacg tccgtgctgt gtcctttcag gctctcttca atgaaactcc
     6481 ccgactctaa atgaagcgtg ttgaggtcac aaagttcgcg taattccact ggcaaatgta
     6541 tctccagaaa gtcgcgagcc gtctccgcat gcattaaaaa ttgtttaaat accgcgtcat
     6601 gcggtgtggt actcggtgca tccatcttcc ctgtcttccg tgtggctttg cgtgaaggca
     6661 gtatccagtc aaggcgcgct atcgtcagcc acctctttat tgtttaccga gcagcgttca
     6721 gagaaatatc aattcgttac aggcgataca tggcacgctt cggcgcggta cgcaaactgc
     6781 tgacgcaaat gccgtcagat gagtagacac taaacaaaaa tcgggcaata ctgcgtgaga
     6841 atttcctcaa agcaggcatc gcctgcttcg ttaacgacag ggtagaaagg tagaagttat
     6901 gattcgcacg atgctgcagg gcaaactcca ccgcgtgaaa gtgactcatg cggacctgca
     6961 ctatgaaggt tcttgcgcca ttgaccagga ttttcttgac gcagccggta ttctcgaaaa
     7021 cgaagccatt gatatctgga atgtcaccaa cggcaagcgt ttctccactt atgccatcgc
     7081 ggcagaacgc ggttcgagaa ttatttctgt taacggtgcg gcggcccact gcgccagtgt
     7141 cggcgatatt gtcatcatcg ccagcttcgt taccatgcca gatgaagaag ctcgcacctg
     7201 gcgacccaac gtcgcctatt ttgaaggcga caatgaaatg aaacgtaccg cgaaagcgat
     7261 tccggtacag gttgcttgat tgttatccct gcggctggtt actcaccagc cgcgacatcg
     7321 tctccagcga atccgttctt aagatataaa gtcgttttag taacaacgga ttatcccccg
     7381 gttttacttt gcctttcatg gttgtcaccg ccaggtgaaa tccggcatcg tttgctgcct
     7441 tcacggcgtt gtcattaaat ccgccaaacg gatacgaaag ataccagaca tgcggattaa
     7501 attgcgccag agcgcggcgt gaacgtgcaa aatcaaacag aatattgtgc tcactacggc
     7561 tcagtaatat gggtcggcga taaccatcta cccgatgcaa aaaatgggta tgtgactgga
     7621 aatcaaatac atcgcgaatt tcgttaagct cagaaacgct cataaattgc agcgattttg
     7681 ggttccactt ctgcgggtga cgtttgatgc gtgaggtaac aataaacgcc gtcgccttca
     7741 tgccatattg tttcaacaca ggatacgcat agcggctcac cgacttgagg ccatcatcaa
     7801 aggtaatcac caccgctcgc gcagggagat tgatcttatt cttcacgtag ccttccagct
     7861 gcaccatgct cagtgtcgcg tatcccctgt cacgcagcca ggccatctgg ttattgaaag
     7921 cgcgtaccga tgtggtcgtc gaagtatggc gaaaacgggt gttttcttcg tcgcgcagaa
     7981 tatggtgata ggttagcacc gacaggccat tatcgggttg ggcatccagt gcgctgatat
     8041 aggccagtcg atcgccaata cggatctgat accaggtttg atttaacctg tctttcagtt
     8101 tatgcaaaat cgggtagcgc aaattgtccg ccagtacccc aaatggcgca cttcccgcac
     8161 tcggcgcgtt atagaccggc gtatctttcc aggtaactaa gttctgatta ctcagcggct
     8221 tgttgaggtc gcccaaaccg tcttcaactt tttgtcgccc ctgaaccggc tcgagatgac
     8281 ctttatcgat aaaacctttg ccaaagccaa aattaaatgc gtaataactt gcggcagtgg
     8341 gctccacggc aatgatttgt ccggcccgaa tattccccac ggtcaccatc ttgtcaccaa
     8401 tttgcgccca gaccgcagca ttttcgatgg tttgcatata acgggcaggt aacgcggcac
     8461 tgacacttgc ggtaaacagc atcagcagga gaataacagc ttgtttgtac atgaaaaaat
     8521 aaccgagggt gaaacaacgc ttttattgta gcaaaagcgc catcagaatc gcgggttaat
     8581 actcatacaa attatgtttg aggacgaaag gcggattttt ttgttgttgg tgccaaagac
     8641 tactcacctc cggcgcaccc agttcgacaa tacgctcgcg aaactctgaa ctggtcatgg
     8701 tttcacggca agccatcatc tgttcaatta acggtaacgt gacaccagaa atcacttcgc
     8761 aacgggagtg tttgtggctt aataatgaag ccacgcgata cggtggcgct ccggctatat
     8821 cggttaagaa gatgacaccc tcaccagagt ccgcttcatg cagagcatcg cacatcatgc
     8881 ggctgagcat attagagctt aatccgcgcc agaaattcac ggcccggcac tgaagaagtg
     8941 ccccatgttt tttctccagc gcatccagta tctcttgcgc ccggtcatcg tgacaggtaa
     9001 ttacccaacc taacatcgcc ttcctcctta gccgaaaatc agtctaccct gaccattgtt
     9061 gataaagggt gatagccgtc aaaactcctc tcccccaaat ccagaggaga ggaaatagcc
     9121 ttagctacgc aaaccacgtc cacgttggat cagcgaccaa cagatcaaat aaaacgccac
     9181 aataaagacc accagtacgc caaaggtagt gaccagcgga acatcattga taccgaggaa
     9241 gccgtagcgg aaaccactga tcatataaac gattgggttc aggtgcgaca gcccttgcca
     9301 gaacggcggc aacaaagtca gtgagtaaaa gaccccgccc aaatacgtga gtggcgttaa
     9361 cacaaaggtt ggcaccaggc tgatgtcatc gaacgttttg gcaaacacac cgttcagcaa
     9421 acccgcaagg gagaacaaca ccgccgtgag caccagcgtt aaggcaacga atacccacga
     9481 atgcacctga aatggcacaa aaaacagtga aattgccgtc accagaatgc caacaaacag
     9541 accacgcgcc acgccaccgc cgacatatcc ggcaataatg acgtgagtcg gaaccggcgc
     9601 taccagcagc tcttcaatat tacgctggaa cttggcacca aaaaatgatg acgcaacgtt
     9661 ggcgtaggca ttggtgatca ccgacatcat gatcagcccc ggtacgatga actgcatata
     9721 gctgaagcca tgcatatcgc caatacgcga accaatcagg ttaccgaaga taataaagta
     9781 aagggtcatg gtgatgactg gcggcaccag cgtctgcacc cagatacgca taaagcgatg
     9841 gatctctttc gcccagatgc tttttagcgc cacccagtaa agatgcatca tgcgcgatct
     9901 ccttgttttt cattaaccag tgaaacaaac agctcttcca gacggttagc tttgttacgc
     9961 atacttaata cctgaatgcc ctgctcactt aactgcgtaa atacgctgtt gatcccctgc
    10021 tcacgcagca cttcaacttc cagcgtcgcg gtatcgacca gtcgatactg atagccatcg
    10081 agcttcggta acgggctttt cggtgcgaga tcgagaataa aggtttccga tttcagcttc
    10141 gccagcagcg ccttcatcga ggtattttcc accagctcac cgtgttgaat aatgccgata
    10201 ttgcggcaca gcatttctgc ttcttccagg tagtgtgtgg tgagaatgat ggtggtgcct
    10261 ttgtcgttta aatccttcaa aaagccccac attgagcggc gaagttcaat atccacgcct
    10321 gcggtcggtt cgtcgagaat cagtagttta ggttcatgca ttaacgcacg ggcaatcatt
    10381 aaacggcgct tcatcccgcc agataacata cgcgcacgtt cgttgcgttt tccccataga
    10441 tcgagttgtt taagatactt ttcgctgcgg atgtacgctt ctttgcgctc cacgccgtag
    10501 taccctgcct gattcaccac aatttgctgc acggtttcaa acgggttgaa gttaaattcc
    10561 tgcggcacca gtcccaactg acgtttagcg ttcacgacat ccttctcgag atcgtaacca
    10621 aatacgctga cccgcccgga ggttttattt accagagagc tgataatacc gatagtggtc
    10681 gatttcccgg ccccgttcgg cccgagaagc gcataaaaat cacccgcttc gacctgcaaa
    10741 tctatcccac gaagcgcctg aacgccgcct ggataggttt ttttaagctg ttgaagttcc
    10801 agtgcaatgg tcataaattt ttacttacct tacgttctta cactttatct gtggtttaaa
    10861 tcgtcccgga gttgccctat attagccaaa cgtaattatt tggttacagg tcgttaacct
    10921 ccatgaaaga catagataca ctcatcagca acaatgcact atggtcaaaa atgctggtgg
    10981 aagaggatcc cgggtttttt gagaaactgg cacaagcgca aaaaccgcgc tttctatgga
    11041 ttggatgttc cgacagtcgc gttcctgcag aacgtttaac cggtcttgag ccgggcgaac
    11101 tctttgttca ccgtaatgtt gctaacctgg tcattcacac tgacctgaac tgcctttccg
    11161 tggttcagta tgcagtggat gtactcgaag ttgaacacat tattatctgt ggccactacg
    11221 gttgcggcgg cgtacaagcc gcagttgaaa acccggaact ggggcttatc aacaactggc
    11281 tgctgcatat ccgcgatatc tggttcaaac atagctcatt gctcggcgaa atgccgcaag
    11341 agcgccgtct ggataccttg tgtgaactga acgtcatgga acaggtgtat aacctgggcc
    11401 actccaccat tatgcaatca gcgtggaaac gcgggcagaa agttaccatt cacggctggg
    11461 cctacggcat tcacgacggc ttgctgcgtg atctggatgt taccgccacc aaccgcgaaa
    11521 cccttgagca acgttaccgt cacgggattt ccaacctcaa gctgaaacac gccaaccaca
    11581 aataaaaatg ccatgccgga tgcaacacat ccggcaactt cacacttact cgtccagcag
    11641 aatcactttg ccgatatacg gcagatgacg gtaacgctgt gcgtaatcaa tgccgtaacc
    11701 caccacaaac tcatccggga tcgagaaacc gataaattct accgggacgt tcacttcacg
    11761 acgggacggt ttatccagca gcgtacaaat cgccagcgac ttcggttcgc gcaggcttaa
    11821 gatctcacgc actttcgaca gtgtattccc cgagtcgatg atatcttcaa caatcagcac
    11881 gtccttgcca cggatatctt catccagatc tttgaggatt ttcacatcac gggtggtgga
    11941 catgccgcta ccgtagctgg aggcggtcat aaagtcgact tcatgagata cctgaacttc
    12001 acggcacagg tccgccataa acataaatga gccacgcagc agacccacca gcaccatatc
    12061 gctgccgctg tctttgtaac gctcagtaat ctgacgaccc agttcggcga tacgcgcttt
    12121 aatctccgct tcggggatca ttacttctac agtatgtttc atatctctaa ccatatgatt
    12181 taaaaacaaa tcacttcgca cgggcaggtt ttggcaccgc aacaaagcgc aagacacgca
    12241 gtataccagt aaaactattc attcgcggaa tctgttaata aagctcgaat tgtgatgacg
    12301 atcacacatg ttaaaaccta taattaattg ctactaaaat attaatgaat tgaaatggtg
    12361 tctctttatg gcaattaaca atacaggctc gcgacgatta ctcgtcacgc taacagccct
    12421 ttttgcagcg ctttgcgggc tgtatctact cattggcgga ggctggctgg tcgcgattgg
    12481 cggctcctgg tactacccta tcgctggcct tgtgatgctc ggcgtcgcct ggatgctgtg
    12541 gcgcagtaaa cgcgccgcgc tttggctata cgcagccctg ctgctcggca ccatgatttg
    12601 gggcgtctgg gaagttggtt tcgacttctg ggcgctgact ccgcgcagcg acattctggt
    12661 cttcttcggc atctggctga tcctgccgtt tgtctggcgt cgcctggtca ttcctgccag
    12721 cggcgcagtt gccgcactgg tggtcgcact gctgattagc ggtggtatcc tgacctgggc
    12781 cggatttaac gatccgcagg agatcaacgg caccttaagc gccgatgcca cacctgctga
    12841 agctatctcc cccgtagccg atcaggactg gcctgcctat ggtcgtaatc aggaaggtca
    12901 acgcttttcg ccgctgaaac aaattaacgc cgataacgtc cataatctga aagaagcctg
    12961 ggtgttccgt actggcgatg tgaagcagcc gaacgatccg ggtgaaatca ccaatgaagt
    13021 gacgccgatt aaagtgggcg acacccttta cctgtgtacc gctcaccagc gcctgtttgc
    13081 gcttgatgcc gccagcggca aagagaaatg gcattacgat cctgagctga aaaccaacga
    13141 gtctttccag cacgtaacct gccgtggtgt ctcttatcat gaagccaaag cagaaaccgc
    13201 ttcgccggaa gtgatggcgg attgcccgcg tcgtatcatt cttccggtca atgatggtcg
    13261 actgattgcg attaacgctg aaaacggcaa actgtgcgaa accttcgcca ataaaggcgt
    13321 gctcaatctg caaagcaata tgccagacac caaaccgggt ctgtatgaac cgacttcgcc
    13381 accgattatc accgataaaa ccatcgtgat ggccggttca gttaccgata acttctcaac
    13441 ccgcgaaacg tctggcgtga tccgtggttt tgatgtcaac accggggagc tgctgtgggc
    13501 ttttgatccc ggcgcgaaag atccgaacgc aatcccgtct gacgaacaca cctttacctt
    13561 taactcgcca aactcctggg caccagcggc ctatgacgcg aagctggatc tggtctatct
    13621 gccgatgggc gtgaccacgc cggatatctg gggcggtaac cgcacaccgg aacaggaacg
    13681 ttatgccagc tcgattctgg cgctgaatgc cactaccggg aaactggcgt ggagctacca
    13741 gaccgttcac cacgacctgt gggacatgga tcttccggca cagccgacgc tagcggacat
    13801 caccgttaat ggtcagaaag tgccagttat ttacgctccg gcgaaaaccg gcaacatttt
    13861 tgtgctcgat cgtcgtaatg gcgaactggt ggttccggca ccggaaaaac cggttcccca
    13921 aggtgcagcg aaaggcgatt acgtaacccc aactcaaccg ttttctgaac tgagcttccg
    13981 tccgacgaaa gatttgagcg gtgcggatat gtggggagcc accatgtttg accaactggt
    14041 gtgccgcgtg atgttccacc agatgcgcta tgaaggcatt ttcaccccgc catctgaaca
    14101 gggtacgctg gtcttcccgg gtaacctggg gatgttcgaa tggggcggga tttccgttga
    14161 tccaaatcgt gaagtggcga ttgccaaccc aatggcactg ccgtttgttt cgaaactgat
    14221 cccgcgtggt cctggcaacc cgatggagca gccgaaagat gccaaaggca cgggtacgga
    14281 atccggcatt cagccacagt acggtgtacc gtatggtgtc acgctcaacc cgttcctctc
    14341 accatttggt ctgccatgta aacagccagc atggggttat atctcggcgc tggatctgaa
    14401 aactaatgaa gtggtgtgga agaaacgtat tggtacgccg caggacagta tgccgttccc
    14461 gatgccggtt ccggtgccgt tcaatatggg tatgccgatg ctgggcgggc caatctccac
    14521 ggcgggtaac gtgctgttta tcgccgctac ggcagataac tacctgcgcg cttacaacat
    14581 gagcaacggt gaaaaactgt ggcagggtcg tttaccagcg ggtggtcagg ctacgccaat
    14641 gacctatgaa gtgaatggta agcagtatgt ggtgatctcc gcaggcggtc acggttcatt
    14701 tggtacgaag atgggcgact atattgtggc ttatgcgctg ccggatgatg tgaagtaaga
    14761 cttgctcaga ttgctgacaa cgtgcgcgtt gttcatgccg gatgcggcgt gaacgcctta
    14821 tccagcctac aaaattgtgc aaaatcaatg gattgcacag ctagcgtagg cctgataagc
    14881 gtagcgcatc aggcagattt gcgtttgtca tcagtttaat gcccggagag atccgggcat
    14941 atttccgaat acggtctttt tataccgtaa accctaacat catccccgta tcttcatgct
    15001 ccagcagatg gcagtgcgcc atataagcat gttctttcgg tgcatcgtga ttaaacttca
    15061 ccagcacttc gctgacatta ccttctacct taacggtatc tttccagccc gcgcgatgag
    15121 ccgctggcgg tttgccattt tctgacaaga tacggaactg cgtgccgtgg atatggaacg
    15181 gatgcagcat catgtcgccc acgccagaga taacccaacg ttcgtattgc cctttcgccg
    15241 ccgcaaacat cggcttgttc atatcaaacg cctgaccgtt gattttgttg gcatggtgga
    15301 aatcgaactt cccgccgtgg ttcatatgat tcatattgcc gtgccccata tggcccatca
    15361 tctggctgtg atccatcccg gccatcgcct gatcgccata tttctccatt agcatctgca
    15421 tccccatcat atcgagcatc gggtccatag agagttgcag cttgcgtacc gtcagccctt
    15481 ccagcgaagg taacgcaggc aggctactta atgtgtctgg caaagcaccg gaggcactaa
    15541 tagcaatcgg ctgaatccgc attaccggat gaggcttatc aaacggcgca atcgccatcc
    15601 ccatctggct gaccggcagc gtcaccaggt caaagggttt gttatcgtta acctccacca
    15661 gcacttcaaa acgctcgccc atcagcaccg gcagttcgct caccttcact ggttcaggta
    15721 gcagaccacc gtcgctggca atcacataca gcgggcgatt gtcgctggtg gcgaaattga
    15781 gcgaacgggc attacagcca ttgagcaaac gcaggcgcag ccaaccacgc ggggcagcgt
    15841 gttgcgggta gattgcaccg ttggtcagca acgtatcgcc aaaccagccc acggcggcgg
    15901 tcatcacatc cagttgataa tcaatctgcc cgtcggcgct aaatttctta tcctgaacga
    15961 tcaccggaac atcatcgata ccccactgtt ttggcagcat taatttcagg atctcgtcat
    16021 cttcaatcac caccagccca gccagcccca tcgccacctg tcgcccggtt ttgccgtgct
    16081 gatgcggatg gaaccagcag gtagcggcag gttgatcaac gttcaacgtc accgagcgct
    16141 tgccacctgg cggaataatt ccctgcgggc cgccgtcgac ttcacccggt acttccagcc
    16201 cgtgccagtg caacgttgtc tcttccgtca gttggttgta gatatcaacc gttaccgctt
    16261 tgccgcgctg taatttcacc gccggcccca gcagattgcc gttatagccc caggtagttg
    16321 cagttttccc gccaaaggtg gactggcctg cgccaatagt taactgaatg cgattacggg
    16381 catcggtcgt gagcaaatca gggatcggta acgttgggcg ttctgccgca aatactgcgc
    16441 ggctccacag cggcaaagcc gaagccacac ccagcgcgac ggaatatttt aagaaatcac
    16501 gacgttgcat agttatttcc ttattcttaa gcaggcgaaa caaaatcaaa cgttgagcat
    16561 agtccttccc cttacgggaa ggtcaagccg cagacacaat ttaatcgaca ataatggtcg
    16621 tcgcctcgct cgcagtgtgc taacgtttat cttctttaag cccctggtag aagcaatgaa
    16681 gacgtttttc agaacagtgt tattcggcat cctgatggcc gtctgcgcaa acagttacgc
    16741 gctcagcgag tctgaagccg aagatatggc cgatttaacg gcagtttttg tctttctgaa
    16801 gaacgattgt ggttaccaga acttacctaa cgggcaaatt cgtcgcgcac tggtcttttt
    16861 cgctcagcaa aaccagtggg acctcagtaa ttacgacacc ttcgacatga aagccctcgg
    16921 tgaagacagc taccgcgatc tcagcggcat tggcattccc gtcgctaaaa aatgcaaagc
    16981 cctggcccgc gattccttaa gcctgcttgc ctacgtcaaa taatccctga tacctttttg
    17041 tagaaatatt gaccgtgcat ccgcggtcaa tgttagctat tatgttgcgc ccttttttta
    17101 cgggtgttaa caaaggaggt atcaacccat ggccgaaaaa aaacagtggc atgaaacgct
    17161 acacgaccag tttgggcagt actttgcggt agataacgtt ctgtatcatg aaaagaccga
    17221 tcaccaggat ctgatcattt ttgagaacgc tgcatttggt cgcgtaatgg cgctggatgg
    17281 cgtagtacaa accaccgagc gcgacgagtt tatctatcat gagatgatga cccatgttcc
    17341 gctactggcc catggtcacg cgaaacatgt gctgattatc ggcggcggcg acggtgccat
    17401 gctgcgtgaa gtaacccgac ataaaaacgt tgagtcaatc acgatggtgg aaatcgatgc
    17461 gggtgtcgta tcgttctgcc gtcagtatct acccaaccat aacgccggta gctacgacga
    17521 tccgcgcttt aagctggtga tcgacgatgg cgtcaatttc gttaatcaaa ccagccagac
    17581 ctttgatgtc attatctccg actgcaccga tcctatcggt cccggcgaaa gccttttcac
    17641 ttcggcattt tatgaaggct gcaaacgttg cctgaatcct ggcggtatct tcgtcgcaca
    17701 aaacggcgtc tgctttttac agcaggaaga agccatcgac agccatcgca aactcagcca
    17761 ttacttcagc gacgttggct tttatcaggc ggcgatcccg acctattacg gcggtatcat
    17821 gacttttgca tgggcgacag ataacgacgc cttacgccat ctctcaaccg aaattattca
    17881 ggcgcgtttt ctcgcctctg gcctgaaatg ccgttattac aatccggcaa tccatacggc
    17941 agcttttgcc ttacctcagt atctgcaaga cgcactggct tcacagccgt cctaaggaga
    18001 agataagaaa ttgaaaaaac tgaaactgca tggctttaat aatctgacca aaagtctgag
    18061 tttttgtatt tacgatatct gctacgccaa aactgccgaa gagcgcgacg gttatattgc
    18121 ttatatcgat gaactctata atgccaaccg tctgaccgaa atcctgtcag aaacctgttc
    18181 cattatcggg gctaatattc ttaacatcgc ccgccaggat tacgaaccac agggtgccag
    18241 cgtcactatt ctggtgagtg aagaaccggt tgacccgaaa ctcatcgaca aaacagaaca
    18301 ccccggccca ctgccagaaa cggtcgttgc ccatcttgat aaaagtcata tttgcgtaca
    18361 tacctacccg gaaagtcatc ctgaaggcgg tttatgtacc ttccgcgccg atattgaagt
    18421 ctctacctgc ggcgtgattt ctccgctgaa ggcgctgaat tacctgatcc accagcttga
    18481 gtccgatatc gtaaccattg attatcgcgt gcgcggtttt acccgcgaca ttaacggtat
    18541 gaagcacttt atcgaccatg agattaattc gattcagaac tttatgtctg acgatatgaa
    18601 ggcgctgtat gacatggtgg atgtgaacgt ctatcaggaa aatatcttcc ataccaagat
    18661 gttgcttaaa gagttcgacc ttaagcacta catgttccac accaaaccgg aagacttaac
    18721 cgacagcgag cgccaggaaa ttaccgctgc gctgtggaaa gaaatgcgcg agatttatta
    18781 cgggcgcaat atgccagctg tttaacggct ctggcggagc tcccaggctc cgccagattt
    18841 atttacttct gctgcacgaa attgcggtaa gccgccacga cctgcagaaa atcctcaacg
    18901 ccgcatagcg acaggctttc ttcgtcgtag tagttcatcc cctcttccat ttcatcgcca
    18961 gcgaattcca gttgattggc gcgaaccatc acctcttcac cgtccatcca cagggtgtat
    19021 tcatgccctg cccgttgcca ggaccgttcg ctacctttca gtgcgtgcgc tgcttgttcc
    19081 acttcatcaa gcaaggccag gttttctttc acctcttcat taaaccagtg cccgaccact
    19141 tcatgcccca tggacatacg cacctttacc actccggtaa tatcgcgcag aaattcgtaa
    19201 tccatagtgt gttcctctgc tcccggcaat gcaccgaaat cgcattgcgc cattgatgta
    19261 attatcgcag ccttaccgga gaaaaacagc ggaacggcga tggtttagaa ataaaaaaat
    19321 gcccgggaat ctcattcacc gggcattgtg tcgtttatgc gcagcgcgtg cgctgacttt
    19381 ttaaaccgca gtctggaaaa tcaccccatc ggctttctcg gtgtactgag aaagctggtt
    19441 gaagttcaga taacggtaag tatcaacggc tgttttatct acctgcgcca cgtaggtctg
    19501 gtactcttcc ggcgtcggca gtttgccaat cagcgccgca acagccgcca gttccgcaga
    19561 agccaggaag acattcgcgc cagtacccag acggttcggg aagttacggg tagaggtgga
    19621 aaccaccgtt gcaccgtccg ccacacgcgc ctggttaccc atacacaggg aacagccagg
    19681 gatctcgata cgcgcaccac tcttaccgaa gacgctgtag tagccttctt cggtcaactg
    19741 tgcggcgtcc atacgggttg gcggtgccac ccacaggcgg gtcggcaact gacctttatg
    19801 cgcatccagc agtttacccg cagcacggaa gtgaccgatg ttggtcatgc aggaaccgat
    19861 aaacacttcg tcgatcttct caccctgtac cgcagacagc ggacgcgcgt catccgggtc
    19921 gttcggagca cacaggattg gctctttaat atccgccaga tcgatgtcga tcactgccgc
    19981 gtattccgca tctgcatcgg cttccagcag ctcaggattc gccagccatt tttccatgcc
    20041 ctgaatacga cgttccaggg tacgacgatc gccgtaacct tccgcgatca tccacttcag
    20101 caggacgatg ttagagttca ggtattcgat gatcggttct ttgttcagct tgatggtaca
    20161 accagcggca gaacgctcgg cggacgcatc ggttagctca aaggcctgct caactttcag
    20221 atccggcaga ccttcaattt ccaggatgcg gccagagaag atgtttttct tgcctttctt
    20281 ctcaacggtc agcagacctt gtttgatcgc atacagcgga atagcgtgta ccagatcgcg
    20341 cagggtgatg cccggctgca ttttgccttt gaagcgcacc agaacggatt ccggcatatc
    20401 aagcggcatt acgccagttg cggcagcaaa cgccaccaga ccagaacccg ccgggaaaga
    20461 gataccgatc gggaaacggg tatgggagtc accaccggta ccgacggtat ccggcagcag
    20521 catacggttc agccaggagt gaatgacgcc gtcacccgga cgcagcgaca caccgccacg
    20581 gttcataatg aagtccggca gcgtgtggtg cgtgttcacg tcaactggct tcggatacgc
    20641 cgcggtgtgg cagaaagact gcatcaccag gtcagccgag aagcccaggc acgccaggtc
    20701 tttcagttca tcacgggtca tcgggccggt ggtgtcctgg gaacctacag aagtcatttt
    20761 cggttcacag tacgcgcccg gacgaatgcc tttcacgcca caggcacggc ctaccatttt
    20821 ttgcgccagc gagaagccgc gatcgctctc agcgacatct ttcgcctgac ggaacacatc
    20881 actgtgcggc agaccaagta cttcacgcgc tttggtggtc aggccacgcc cgataatcag
    20941 cggaatacgg ccaccagcac gcacttcatc aatcagcacg tcggttttca gttcgaaggt
    21001 cgccagcagt tcgccggttt cgtggttacg cacttcacct ttgtacgggt aaacgtcaat
    21061 cacgtcgccc atgttcaggt tagagacgtc gacttcgatt ggcagtgcac ccgcgtcttc
    21121 catcgtgtta aagaagatgg gtgcaatttt accgccgagg cacaaaccac cgccgcgttt
    21181 gttcggcaca tgtggaatat catcgcccat aaaccacaga acggagttag tggcggattt
    21241 acgcgaagaa cccgtaccca caacgtcacc gacgtacgcc agcgggaaac ctttctgttg
    21301 cagagcttcg atttgcttga tcggaccaac aacaccaggc tggtctggct caataccttc
    21361 acgggcgttt ttcagcatcg ccagcgcgtg cagtgggata tccgggcgtg accacgcatc
    21421 cggtgccgga gaaaggtcat cggtgttagt ttcgccagtg actttgaaga cagtaacggt
    21481 cagtttttca gccagcgccg ggcgattcag gaaccattcg gcatccgccc aggactgcat
    21541 aacctgcttc gcatattcgt tgcctgcttt cgctttctct tctacgtcat agaagttatc
    21601 gaacatcagc agcgtgtgag aaagtgcttt ggcagcaata ggtgccagtt tggcatcatc
    21661 cagcgcgtcg atcagcggat gaatgttgta accaccctgc atggtgccca gcagttcgat
    21721 ggctttttcc ggagtcagca gaggggattt ggcttcgcct ttcgcgatag cagccaggaa
    21781 gcctgctttg acataggcgg cttcatcgac gcctggggga acacggttgg ttaacagatc
    21841 taacaggaat tcttcttcgc ccgcgggcgg gtttttcagc agctctacaa gtgcggccat
    21901 ttggtttgca tccaggggtt tgggcgcaat cccctcagcg gcacgctcag ctacgtgctt
    21961 acggtattct tctagcacga cggttctcct cgctctcatt gtcatagtgc ggcaggcgat
    22021 tctcttcacg ctcctgtgag acagcagttt gtagggtaaa tgcccagtac cgcaacgggc
    22081 agaatagcag gattttgacg aggtgttaat ctgtttacaa aaaagcaaca taaaaaagtg
    22141 gctgaatcgt taaggatggt ctagagattg tttccctccg taaaaacttc gttaattcgc
    22201 atggtgataa tcacctttct caacgaatcc caagattagt caaaatttaa actaccgcct
    22261 ctttatactc ggattcacag cacctgcggg tggcagttcg ccgaccattg cgatttcctt
    22321 gagatccgaa ttatgaaaat gactttgccg tttaaacccc atgtgctggc gctaatttgc
    22381 agtgccgggc tttgtgccgc ctctaccggg ctatatataa aaagccgcac agtggaagcg
    22441 cctgtggaac cgcaatcgac acaactggct gtgtctgacg ctgccgcggt tacgtttcct
    22501 gcaacggttt ccgcacctcc cgtaacaccc gccgtcgtca aatccgcatt cagcactgca
    22561 caaatagatc aatgggtcgc gcccgtcgcg ctgtatcccg acgccctact ttcgcaggtg
    22621 ctgatggcat caacctatcc gacaaacgtt gctcaagcag tgcaatggtc gcacgataat
    22681 ccacttaaac aaggcgatgc tgctattcag gcggtatctg accagccgtg ggacgccagc
    22741 gttaaatcac tggtggcctt tccacaattg atggcattga tgggcgaaaa cccgcaatgg
    22801 gtgcaaaacc tgggcgatgc ttttctggcc cagccgcagg acgtgatgga ctcggtacag
    22861 cgattgcggc aactggcgca acaaaccggc tcgctgaagt catcaaccga acagaaagtt
    22921 attaccacaa cgaagaaagc tgtaccggta aaacagacag tcacggcacc cgtcatacca
    22981 tccaatacag ttttaactgc caaccccgtc attacagagc cggcaacaac cgtcatttcc
    23041 attgagcccg ccaatcctga tgtggtctat attcccaact acaacccaac cgtggtttac
    23101 gggaactggg ccaatactgc gtatccgccg gtttatctgc caccaccagc cggagaaccg
    23161 tttgttgaca gctttgtacg cggattcggc tatagcatgg gcgttgctac cacgtacgca
    23221 ctattcagca gcatcgactg ggacgacgac gatcatgacc atcatcatca tgacaatgat
    23281 gattatcatc accacgatgg cggtcatcgt gacggtaatg gctggcaaca caacggcgac
    23341 aacatcaata tcgacgtcaa caatttcaac cgtatcaccg gtgagcatct tactgataag
    23401 aatatggcat ggcggcacaa tccaaactac cgtaatggtg tgccctatca tgatcaggat
    23461 atggcaaagc ggtttcatca aaccaatgtc aacggcggaa tgagcgccac gcaattacct
    23521 gccccaacgc gcgacagcca gcgtcaggcg gcagcaaatc agtttcagca acgaacacac
    23581 gccgcaccag tcattacacg agatacccaa cgtcaggcag cggcacagcg gtttaatgaa
    23641 gctgaacact atgggagcta tgacgacttc cacgacttca gccgtcgcca accactgacc
    23701 cagcaacaaa aggacgccgc tcgtcagcgt tatcagtccg cctcgcctga gcagcgccag
    23761 gcagttcgcg agagaatgca gactaacccg aagatccagc agcgaagaga ggcagcgcgt
    23821 gagcgcattc agtccgcctc gcctgagcag cgccaggcgg ttcgcgagaa aatgcagact
    23881 aacccgcaga accagcagcg aagagacgca gcacgtgagc gtattcagtc cgcatcacca
    23941 gagcagcgcc aggtgtttaa ggaaaaagta cagcagcgcc cactgaatca acagcaacgt
    24001 gataacgccc gccagcgtgt tcaatcggca tcacctgaac aacgtcaggt ttttcgggag
    24061 aaagttcagg agagccgccc acaacgtcta aacgacagta accatactgt caggctgaat
    24121 aacgagcaac ggtcagcagt acgcgaacgt ctctctgaac gtggagcaag aagactggaa
    24181 aggtaaattg cagacgtaaa aaaagcggcg tggttagccg cttttttaat tgccggatgt
    24241 tccggcaaac gaaaaattac ttcttcttcg ctttcgggtt cggcaggtcg gtaatgctac
    24301 cttcgaacac ttctgccgcc aggcccacag actcgtgcag agtcgggtgc gcgtggatgg
    24361 tcagtgcgat gtcttcagca tcacaaccca tttcgattgc caggccgatt tcacccagca
    24421 gctcgccgcc gttagtaccg acaatcgcac caccgatcac acggtgagat tctttgtcga
    24481 aaatcagctt ggtcataccg tctgcgcagt cggaagcgat agcacgacca gaagcagccc
    24541 acgggaaggt ggcggtttca tagctgatgc ctttctcttt cgcttctttc tcagtcagac
    24601 ccacccatgc aacttctggt tcggtatagg cgatggacgg gataactttc ggatcgaagt
    24661 agtgtttctt accggcgata acttcagcgg caacgtgacc ttcgtgaaca cctttgtgtg
    24721 ccagcatcgg ttgaccgacg atatcgccga tagcaaagat gtgcggtacg ttggtacgca
    24781 gctgtttgtc aacgcggatg aaaccacggt cgtcaacttc cacgcctgct ttgcctgcgt
    24841 cgaggttttt accgttcggc acacgaccaa tcgctaccag cacggcgtcg taacgctgcg
    24901 gttcagcggg tgcttttttg ccttccatcg tcacataaat gccgtcttct ttcgcttcaa
    24961 cggcggtaac tttggtttcc agcatcaggt tgaatttctt gctgatacgc ttggtgaaga
    25021 ctttaacgat gtctttgtca gctgccggga taacctggtc gaacatttca accacgtcaa
    25081 tctgtgaacc cagcgcgtgg taaacggtgc ccatttccag accgatgata ccgccaccca
    25141 ttaccagcag gcgttctggt acttctttca gttccagcgc gtcagtggag tcccagatac
    25201 gcggatcttc atgcggaata aacggcagtt ggatcgggcg agaacccgct gcaatgatcg
    25261 cgttgtcgaa gttgatcacg gttttgccgt tctcaccttc aacttccagg gtgttagccc
    25321 cggtgaattt acccagaccg ttgaccactt tgactttgcg gcctttcgcc ataccagcca
    25381 gaccaccggt cagctgattg atcactttct ctttccaggt acgaatcttg tcgatatcgg
    25441 ttttcggttc gccgaagacg ataccgtgtt cagccagcgc tttggcttct tcgataactt
    25501 ttgctacgtg cagcagtgct ttagaaggga tacagccgac gttcaggcaa acaccgccaa
    25561 gggtgttgta acgttctacg attacggttt ccagacctaa atcagcgcaa cggaaggcag
    25621 cggagtaacc tgcggggcct gccccaagta ccacgacctg agttttgatt tcagtactca
    25681 tcatgacctc tatatattta tctccggcgg tcatacccgt cgtctttcag gccgcagcgg
    25741 cgttagcttc acgccctcac cccagtcact tacttatgta agctcctggg gattctggcg
    25801 cttgctacct tgctgcaccc agaaatccat agggtatgtg aagtaatacc ctaaccacca
    25861 ccgggtcgtt ctatccgtcg gtattttaca aaattgttaa caatttttaa acaacaaacg
    25921 gcaaccgatt tgtctattcg ctaataacct caatacattc atgagattac cagaaaaaag
    25981 ccggccgttg ggccggctct tttacttaca tcaccagacg gcgaatgtca gacagcgtgt
    26041 tgttaatgat ggtaatgaaa cgggcaccat cagcaccgtc gatcacgcgg tggtcgaagg
    26101 agagagaaat cggcagcatc agacgcggca cgaactcttt accattccac accggctcca
    26161 tcgcggactt ggaaacgccg aggatagcca cttccggcgc gttcacaatc ggcgcgaagt
    26221 gggtagtacc caggccgccg atgctggaga tggtgaagca accgccctgc atttcgcccg
    26281 cagtcagctt accgtcacgc gctttcttag aaatagtcat cagctcgcga gacagctcga
    26341 tgatgccttt cttgttgacg tctttgaata ccggaacaac cagaccgttc ggggtatcca
    26401 ccgccacacc gatgttgatg tatttcttca gggtcagacg ctgaccgtct tccgacagcg
    26461 aactattgaa gcgaggcatc tgctcaagag ctgcagcaac ggctttcatg atgaagacaa
    26521 ccggggtgat cttcacatcc agcttacgtt tcgccgcttc ttcgttctgc tgtttacgga
    26581 acgcttccaa ctcggtgata tcggttttgt cgaagtgagt aacatgcggg atcattaccc
    26641 agttacggct caggttcgca ccagagattt tctggatgcg gcccagttcc acttcttcga
    26701 tttcaccaaa cttgctgaag tccaccttcg gccacggcag catgccaggg ataccaccgc
    26761 cagtcgctgc cggagctgct tctgcacgtt tgatagcttc tttcacgtaa gcctgaacgt
    26821 cttcgcgcag gatacgacct ttacggccag tgcccttcac tttcgcaagg ttaacaccaa
    26881 actcgcgtgc cagacggcgg atcagcggag tcgcgtgaac ataagcgtcg ttttcagcaa
    26941 attcagattt gccttccgct ttcgcagctg gtgctgctgc cggggcttca gcttttgctg
    27001 ccggtgccgg cgctgccgct tcctgtttcg caggagctgc cgcaggcgct gcgccttcaa
    27061 cttcgaagat cataatcagc gagccagttt tcactttatc gccaacgttg actttcagtt
    27121 ccttcacgac gcctgcaaac ggcgccggaa cttccataga agctttgtcg ccttctacgg
    27181 tgatcagtga ctgttcagcg gcaactttgt cgcccacttt caccatcact tcagtcactt
    27241 caacttcgtc accgccgata tccggaacgt taacttcttt cacgccagcc gctggtgcag
    27301 gggccgctgc cggagctgct tcctgtttag cggccggagc tgccgcgcct gcttcacccg
    27361 cgacttcgaa gaccataatc agcgagccgg tagacacttt gtcacccacg ttcactttga
    27421 tctctttcac ggtgccagca aacggagccg gaacttccat agaagccttg tcgccttcta
    27481 cggtgatcag cgactgttca gcttcaactt tatcgccaac tttcaccagg atttcggtca
    27541 cttcaacttc gtcgctgccg atatccggaa cgttaacgtc ttttgccgcc gcagccgctg
    27601 gtgctgctgc cggagctgct tctttcttct cttctgcctg agcaggtgca gcgtctgctg
    27661 caccgtcggc ggaatcgaaa atcataatca gtgcgccggt ctgggtttta tcgccaacag
    27721 agactttgat ctctttaacg atacccgcct gcggagacgg aacttccata gaggctttgt
    27781 cgccttctac ggtgatcagc gactgttcgg cttcaacttt gtcgcccact ttgaccagga
    27841 tctcggtgat ttcaacttca tcagccccga tgtccggtac tttgatttcg atagccatta
    27901 ttcttttacc tcttacgcca gacgcgggtt aactttatct gcatcgatgt tgaatttggc
    27961 gattgcgtca gcaaccactt tcttatcgat ttcgccacgt ttagccagtt cgcccagcgc
    28021 cgcaaccacg acataagaag catcaacttc gaagtggtga cgcaggttct cacggctgtc
    28081 ggaacgaccg aagccatcag tacccagtac gcggtagtcg tcagccggta cgtaagtacg
    28141 gacctgctca gcgaacagtt tcatatagtc ggtagatgcc actgccggag cgtcgttcat
    28201 cacctgagcg atatacggaa cgcgcggagt ttccagcggg tgcagcatgt tccagcgttc
    28261 acaatcctga ccatcacgcg ccagctcggt gaaggaggtc acgctataaa cgtcagaacc
    28321 tacgccgtaa tctttcgcca ggatctcagc tgcttcacgg acgtgacgca ggatagaacc
    28381 ggagccgagc agctgaactt tacctttgct accttcaata gtttcgagtt tgtagatacc
    28441 tttacggata ccttcctcag caccttccgg cattgccggc atgtggtagt tttcgttcag
    28501 cgtagtgatg tagtagtaaa cgttctcttg tttttcaccg tacatacgct ccagaccgtc
    28561 atgcatgatg acagcaactt cgtaagcgta agccgggtcg taagagatac agttcgggat
    28621 agtcagcgac tgaatgtggc tgtgaccatc ttcgtgctgc agaccttcgc cgttcagggt
    28681 ggtacgaccg gaagtaccgc cgatcaggaa gccacgcgct tgctggtcgc cagccgccca
    28741 gcacagatcg ccaatacgct ggaagccgaa catcgagtaa tagatgtaga acgggatcat
    28801 cggcagattg ttggtgctgt aagaggtcgc cgctgccagc caggaacaac ctgcgcccag
    28861 ctcgttgatc ccttcctgca gaatctgacc tttctcgtct tctttatagt aagcaacctg
    28921 ctcgcggtcc tgcggggtgt actgctgacc gttcgggctg taaataccaa tctgacggaa
    28981 cagaccttcc ataccgaaag tacgcgcttc gtcggcgatg atcggtacca gacgatcttt
    29041 gatcgacttg ttcttcagca tcacgttcag agcacgaacg aaagcgatag tggtagagat
    29101 ctctttgctc tgctcttcca acagcgcgcc gaagtcttgc aggctcggca gctcaagctt
    29161 ctcggtgaag ttcggctgac ggcttggcag ataaccgtgc agtttctgac gctgagcgtg
    29221 cagataggta tgctcttcag aaccttccgg gaaggtgatg tacggcagtt tttcgatatc
    29281 tgcatcagac accggcacat tgaaacggtc gcggatatga cgcacaccgt ccatgttcat
    29341 tttcttaacc tggtgcgcga tgtttttacc ttcagccgcg tcgcccatgc cgtaaccttt
    29401 aatggtatga gcaaggatta ctgtcgcttt gcctttggtt tcctgcgctt tcttgaatgc
    29461 agcgtagatt ttcttcggat cgtgaccacc acggttcagt gcccagatct gctcgtcagt
    29521 ccagtctgca accagtgctg cggtttcagg atatttaccg aagaagtgtt cacgaacgta
    29581 cgcaccatct ttcgatttga aggtctggta gtcgccgtca acggtttcgt tcatcagctg
    29641 gatcagttta ccgctggtat ccttacgcag cagttcatcc caacggctac cccacatcac
    29701 tttgatcacg ttccagccag caccttcgaa gatgccttcc agttcgttga tgatcttgcc
    29761 gttaccggtg accgggccgt caagacgctg caggttacag ttgataacga agaccaggtt
    29821 atccagtttt tcacgggtag cgatggtgat cgcacctttg gattccggtt cgtccatttc
    29881 accgtcaccg aggaacgcgt aaacggtttg tttagaggta tctttcaggc cacggtgttc
    29941 cagatatttc aggaatttag cctggtaaat agcaccaatc ggacccagac ccatagatac
    30001 ggtcgggaac tgccagaatt ccggcatcag tttcgggtgc ggataggaag agaggccatt
    30061 gccgtgaact tcctgacgga agttatccag ctgctcctga gtcagacgac cttccaggaa
    30121 agcacgagcg tacacgcccg gggagatgtg gccctggaag taaaccaggt cgccgccatc
    30181 ctgctcgttg cgtgcacgga agaagtggtt aaagcacaca tcataaatgg ttgcggaaga
    30241 ctggaaggac gccatatggc cgcccagttc gaggtctttt ttcgacgcac gcagcaccgt
    30301 catgatggcg ttccagcgga tagctgaacg aatacggcgt tccagttcca gattacccgg
    30361 atactccggt tgttcttcaa cggggatggt gttgatgtag ttgctgatac ctgtgcctgc
    30421 ggctacgttt acaccgcctt tgcgggcttc agcaagcagt tggtcgatca gatactgagc
    30481 acgctcaaca ccttcttcac ggatgaccga ttcgatcgcc tggagccagt cgcgagtttc
    30541 gatcggatcc acgtcatttg ggaaacgttc tgacatgggt tattccttat ctatctaata
    30601 acgttgagtt ttctggaacc tgtcccattg aactctcgcc ggaaagctca ataagacagg
    30661 ttctacgttt agttgccgcg cttttatatg cgcttgattt acaacatctt ctggataatt
    30721 tttaccagaa aaatcactaa ttctttcgtt gctccagacg acgcagagaa cgctcacggc
    30781 ggctctcttc acgacttctg tcgagcaaaa tttcttcgat aaaggccaga tggcgatgcg
    30841 atgcttcgcg cgcttcttcc ggcttaccgg ccataatcgc ttcaaatatg cgggtgcggt
    30901 gactactcac cagcggcagc atctcgcgac gcgaatagag caattcgaag ttctggcgga
    30961 cattctgggc caacatcggc tccatacacc ttagcagatg aagcagaacc acattgtggg
    31021 ccgcttcggt gacggcaatc tgatactgga gtacggcgtt tgattccgcg tccagatcgc
    31081 cagactgctg cgccagctct atggcgtggt ggagttcacg gatgcgttcc ttgtcttcat
    31141 cggtactacg cagcgcggcg taataagcgg cgataccttc cagggcgtgt cgtgtttcga
    31201 gcaagtcata ctgtgactca ggatggtcgg agagcagctc caccagcgga tcgctgaagc
    31261 tttgccatag gctgctctgg acaaaagtgc cgccaccctg gcgacgaagc aacaagccct
    31321 tcgcttcgag acgttgaatc gcctcacgca aggagggacg ggagacgtca aactgttttg
    31381 ccagttcgcg ttccggtggg agtttttcgc ccgggcggag agtgccttcg aggatcaaaa
    31441 actccagttg ctgctcaatc acatcggaga gttttggttg gcggattttg ctgtaggcca
    31501 tgagttcctg tcttaagcca cttgccgaag tcaattggtc ttaccaattt catgtctgtg
    31561 acgctaaagt aacaaagtat tcaccttatg tccatacagg ttttgattga aatcatgaaa
    31621 ctgtgcacat tttaacaact tgacatatat aacgtttcaa agttgtaact atgcacaaat
    31681 gtagacttta cgtaggaaag gagtttttta acgattatta aactataaaa atccgaattg
    31741 aaccgattca cttaccaatt ttgtgatttt taattcaatt aaaacgaatt taaattcatt
    31801 ctacatattg agaggggttg aggctgagct ttacaaacgg tttcttttta agcaactcat
    31861 cttcaaccat gcataaagcg ggtgcattcg ctgccgcata ccattattct tgatctgacg
    31921 gaagtctttt tgtaacaatt caaacttctt tgatgtaaac aaattaatac aacaaacgga
    31981 attgcaaact tacacacgca tcactgcgta gatcaaaaaa acaaccaccg cacgaggttt
    32041 catgatggaa ggtcaacagc acggcgagca gctaaagcgc ggccttaaaa accgccatat
    32101 tcagcttatc gcgctgggtg gcgcgatagg gaccgggtta ttcctgggta gcgcctccgt
    32161 aatacagtcc gcagggccag ggattatcct gggttacgcc attgctggtt ttatcgcctt
    32221 tctgatcatg cgtcagctgg gtgaaatggt ggtcgaagaa cctgtcgcag gctcctttag
    32281 ccactttgct tataaatact ggggcagttt tgccggtttc gcctctggct ggaactactg
    32341 ggtactgtac gttttagttg ccatggctga gctgactgcc gtgggtaaat acattcagtt
    32401 ctggtatccg gaaatcccca cctgggtttc tgccgccgta ttctttgtgg tgattaacgc
    32461 catcaacctg accaacgtta aagtgtttgg cgagatggag ttctggtttg ccattatcaa
    32521 agttatcgcg gtggtagcga tgatcatctt cggcggctgg ctgctattca gtggcaacgg
    32581 cggcccgcag gcgaccgtta gcaacctgtg ggatcagggt ggtttcctgc cgcacggctt
    32641 caccgggctg gtgatgatga tggcgattat catgttctcg ttcggtggtc tggaactggt
    32701 ggggatcacc gcagcagaag ctgataaccc ggagcaaagt ataccgaaag caactaacca
    32761 ggttatctac cgcatcctga ttttctatat tggttcgtta gccgttctgc tctcactgat
    32821 gccgtggacc cgcgttaccg ccgataccag tccgtttgtg ctgatcttcc acgagttagg
    32881 cgataccttt gtggcgaatg cgctgaacat cgtggtactg actgcggcgc tctccgtgta
    32941 caacagctgc gtatattgca acagccgtat gctgtttggt ctggcacaac agggtaatgc
    33001 gccaaaagcg ctggcgtctg tcgataaacg tggtgtacca gtaaatacca ttctggtgtc
    33061 tgcactggta acggcgttgt gcgtactgat taactacctt gccccagagt ccgctttcgg
    33121 actgttaatg gcgctggtgg tatctgcact ggtaatcaac tgggcgatga ttagcctggc
    33181 gcatatgaaa ttccgtcgcg ccaagcagga acaaggcgtg gtaactcgct tccctgctct
    33241 gctttatccg ctgggtaact ggatctgcct gctgtttatg gcggcggtac tggtgattat
    33301 gctgatgacc ccaggaatgg cgatttcggt atacctgatc ccggtatggc tgatcgtgtt
    33361 aggtatcggc tatctgttta aagagaaaac cgccaaagcc gtaaaagcgc attaatctct
    33421 ctacgccctc acccgtacag ggtgagggca ataatcttta caccaacgcc ccgtaaatcg
    33481 tcagtagtgc aatcaccacc acgaccacga acgaggtttt cttcgccatt gaaaccgctg
    33541 ccttcggcgt ctccacctta tcgacatgcg gttcacgcgc cagagagaac tgcgccagac
    33601 gcgttaacac ctgatactgc gaagtatgga aatcacccag cgaagcaaac caggccggta
    33661 acgctttctc accatgaccg atcaaggcat ataccacacc cgcaagacga accggcaccc
    33721 aatccagtac atgaagcacg gcatcaatgc cggactgtaa acgatgatgc ggcgtctgat
    33781 atcgcgccag ccagtattgc catgcacgca aaaacgcata ccccatcagc gtaacgggtc
    33841 cccaggttcc ccccacaatc agccagaaca gcggtgcaag ataaaaacga aagttaatcc
    33901 acagcaatgc attttgcagc tcacgcaaat actcacgttc gtcgcagcct gccgggacgc
    33961 cgtgaatcat ggtgagttcg ccagccatcg tggcacgggc atggctatca ttacgtgaag
    34021 cagctgtcag ataagcatga taatgaagac gaactttacc tgcgccaata cacagcaaac
    34081 caatcagcag ccacaccagt agcgtgggaa cgttgaacaa tactccctgc aatgcgcgta
    34141 acagtaaaaa agtcacgccc atcgcaataa tggtcatgcc taacgtgcgc ccgagagaaa
    34201 aatgtttcac ccgccgaaag aacgcttcaa gacgatgatc aagctgccag tgctcgccca
    34261 acttaaacag gcgctcgaaa attaacacca gtaaggttgt aaatagcgtc atgttgtctc
    34321 cttgctgacc agcacacgaa accgtgccca atcaaatgca ggaccgggat cggttttccg
    34381 atccggcgca atatcacaat ggcccgtcat gtttttagcg atatccggat agcaatcaat
    34441 cagtgcccgc gtaaccgccg caagctgttg atactgcgca tcggtatacg ccagcgtatc
    34501 ggtgccttca agctcaatcc caatagaaaa atcattgcag cgttcgcgcc cctgatactg
    34561 agagactccc gcatgccatg cacgtttatc gaaaggaaca tactggacta tttcaccatc
    34621 acggcgaatc aaacagtgag cggagacgcg caaatgggcg atctcagcaa agaaaggatg
    34681 tgcctgcgga tcaatagttc cagtgaataa tgcgtcgatc cacggaccgc caaactcgcc
    34741 tggcggcagg ctaatattgt gcaccaccag cagggtgggt gtttcgtcat ccgggcggca
    34801 atcgtaatgt ggtgagggaa cgcggcgcgc gccaaccagc cacccctgtt ctaacaacat
    34861 gcaggatctc cttatatgtg gtgctaatac ccggttcaga gtagcatgtt tctaccttat
    34921 gattcgttag ctatctggag ttttaacatg ccgcctcgcc gctataaccc tgacacccga
    34981 cgtgacgagc tgctggaacg cattaatctc gatatccccg gcgcggtggc ccaggcgctg
    35041 cgggaagatt taggcggaac agtcgatgcc aacaatgata ttacggcaaa acttttaccg
    35101 gaaaattctc gctctcatgc cacggtgatc acccgcgaga atggcgtctt ttgcggcaaa
    35161 cgctgggttg aagaggtgtt tattcaactg gcaggcgacg atgtcaccat aatctggcat
    35221 gtggatgacg gcgatgtcat caatgccaat caatccttgt tcgaacttga aggcccatcc
    35281 cgcgtgctgt taacgggcga acgcactgcg cttaattttg tgcaaaccct ttcaggagtt
    35341 gccagtaagg tacgccacta tgtcgaattg ctggaaggca ccaacacgca gttgttggat
    35401 acgcgcaaaa ccttacccgg cctgcgttca gctctgaaat acgcggtact ttgcggcggc
    35461 ggagcgaatc accgtctggg gctttctgat gccttcctga tcaaagaaaa ccatattatt
    35521 gcctccggct cagtgcgcca ggcggtcgaa aaagcgtcct ggctgcaccc ggatgcgcca
    35581 gtagaagtcg aagtagagaa tctggaagaa cttgatgaag ccctgaaagc aggagccgat
    35641 atcatcatgc tggataactt cgaaacagaa cagatgcgcg aagccgtcaa acgcaccaac
    35701 ggcaaggcgc tactggaagt gtctggcaac gtcactgaca aaacactgcg tgaatttgcc
    35761 gaaacgggcg tggactttat ctccgtcggt gcgctaacta aacacgtaca agcactcgac
    35821 ctttcaatgc gttttcgcta atagttgaca gatttatccg ctccatcgcg ggcggataat
    35881 ctccccttcc ccaactttct tcgtaacgcc tcgcaaattt cttgtctttc gctgcaacga
    35941 aataaaaaac ctcggaatct gctttcccgt ttcgtttttt gcccctcgcc tgtgctgatg
    36001 gcgtttgcca aagtagcgcc aaccaaatca aggagcgaaa cagatggaca agcaacgcgg
    36061 ttttacactt atcgaactga tggtggttat tggcatcatt gccattttaa gcgccattgg
    36121 tattcccgct tatcaaaact acctgcgcaa agccgcactc accgacatgc tacaaacctt
    36181 tgtgccttac cgtaccgccg tagagttgtg cgcgctggaa catggtggat tagatacctg
    36241 cgacggtggc agcaatggca ttccctcgcc taccaccacc cgctatgttt cagccatgag
    36301 tgtggcaaag ggcgtggtgt cgctgaccgg gcaagaaagt ctcaatgggc taagcgtcgt
    36361 catgacaccg ggttgggata acgcaaacgg cgtcaccggc tggacgcgca actgcaatat
    36421 tcaaagtgac agcgcattgc agcaagcctg cgaagatgtc ttccgctttg atgacgccaa
    36481 ctaaggagcg gcaatgaata ttccacagct cactgccctg tgtctgcgtt atcatggagt
    36541 cttgctggat gccagcgaag aggtggttca tgttgcggta gtcgatgcac cttcgcatga
    36601 gctactggac gcattgcatt tcgctaccac caaacgtatt gagatcacct gctggacgcg
    36661 ccaacaaatg gaaggtcacg ccagtcgcac acaacagaca ttgcccgtag ctgttcagga
    36721 gaagcatcag cccaaagcag agttgctaac tcgaacgtta caatctgcgc tggaacaacg
    36781 cgcgtctgat attcatatcg aaccagcgga caatgcctac cgcatccgct tgcgtatcga
    36841 cggcgtattg catcctttac cggatgtttc accggatgcc ggagtcgcat taaccgccag
    36901 attaaaagtg ctgggaaacc tggatattgc ggaacatcgc ctgccgcagg acgggcaatt
    36961 cactgtcgaa ctggcaggaa acgccgtctc atttcgtatt gcgaccttac catgtcgggg
    37021 tggtgaaaag gtggtattaa ggttgttaca gcaggtgggt caggcactgg atgtcaacac
    37081 gcttggaatg cagccgttac aactggcgga ctttgctcat gccttgcaac aaccacaggg
    37141 actggtgctg gtaactggcc ctaccggcag cggcaaaacg gtcacgcttt atagtgccct
    37201 gcaaaagctg aataccgctg acattaatat ttgtagcgtc gaagatccag ttgagatccc
    37261 catagccgga ctaaaccaga cgcaaatcca tccgcgtgcc ggactcacct ttcagggcgt
    37321 tttgcgtgcg ttattgcgcc aggatcctga cgtcatcatg atcggagaga tccgcgatgg
    37381 cgaaacagca gagatcgcta ttaaagcggc gcaaactggt cacctggtgt tgtctaccct
    37441 acacactaat tccacctgcg aaacgctggt acgtttacag caaatggggg tcgcccgctg
    37501 gatgctatca tcggcgctta cgctggtaat agcccagcgt ctggtacgca aactttgccc
    37561 acattgtcgc cggcagcaag gggagcccat ccacattcca gacaatgtat ggccatcgcc
    37621 gctgccccac tggcaggcac ccggttgtgt acattgctac cacggttttt atggtcgtac
    37681 ggccttattt gaagttctgc ccataacgcc ggtcattcgt cagcttattt ccgctaatac
    37741 cgacgttgaa tcgctggaaa cgcacgcacg acaggcgggt atgcgtacgc tttttgaaaa
    37801 cggctgcctg gccgtagagc aaggcttaac cacctttgaa gagttaatcc gcgtactggg
    37861 gatgccgcat ggcgagtaag caactctggc gctggcatgg cataaccggc gacggcaatg
    37921 cgcaagatgg gatgctatgg gcagagagcc gtactttact gcttatggca ctacagcaac
    37981 agatggttac cccactaagc ctgaagcgaa tcgccatcaa ttctgcgcag tggcgaggag
    38041 ataaaagcgc ggaagtcatt catcaactgg cgacgctact caaagcaggg ttaacgcttt
    38101 ctgaagggct ggctctgctg gcggaacagc atcccagtaa gcaatggcaa gcgttgctgc
    38161 aatcgctggc gcacgatctc gaacagggca ttgctttttc caatgcctta ttaccctggt
    38221 cagaggtatt tccgccgctc tatcaggcga tgatccgcac gggtgaactg accggtaagc
    38281 tggatgaatg ctgctttgaa ctggcgcgtc agcaaaaagc ccagcgtcag ttgaccgaca
    38341 aagtgaaatc agcgttacgt tatcccatca tcattttagc gatggcaatc atggtggttg
    38401 tggcaatgct gcattttgtt ctgccggagt ttgccgctat ctataagacc ttcaacaccc
    38461 cactaccggc actaacgcag gggatcatga cgctggcaga ctttagtggc gaatggagct
    38521 ggctgctggt gttgttcggc tttctgctgg cgatagccaa taagttgctg atgcgccgac
    38581 cgacctggct tatagtgcgg cagaaattgc tgttacgcat cccgattatg ggttcactga
    38641 tgcggggaca aaaactcacg cagatcttta cgattctggc gctgacacaa agtgcaggca
    38701 ttactttttt acagggcgta gagagcgtca gagaaacaat gcgctgcccg tactgggtgc
    38761 aacttctgac acaaatccag cacgatatca gtaacggtca acccatctgg ctggcgctaa
    38821 aaaataccgg tgagtttagc ccgctctgtt tgcaattagt gagaacagga gaggcatccg
    38881 gctctctgga tctcatgtta gacaacctcg cccatcatca tcgggaaaac acaatggcgc
    38941 tggcggataa cctcgcagcc ttactggaac cggcgttgct gatcataacg ggaggaatta
    39001 ttggtacgct ggtggtggca atgtatctgc caattttcca tttaggcgat gcgatgagtg
    39061 ggatgggata acgctggcgt gttgctccac gccagcgttg ggagattaca ggttgttgaa
    39121 gatgcggttt tcttgttcct gcacacgaat aaacgtggtg cgcttggtca gctctttcag
    39181 gcgtgaagcc ccaacgtatg tacaagctga acgcaggccg cccaaaatat ctcgcgcggt
    39241 attttcaacc gggcctcgca gcggcagctt aacggtttta ccttctgctg cgcgatattc
    39301 cgcaacgccg ccaacgtgac gtttcatcgc agactcggag ctcatgccgt agaacagcat
    39361 aaatttctcg ccgttctcct caacgatgcg accgccgctc tcttcgtggc ccgccagcat
    39421 gccgccaagc atgacgaaat cggcaccgcc gccaaaggct ttcgccacat cgcccggcgt
    39481 ggtgcagcca ccatcgctga cgatcattcc gcccagaccg tgcgcagcat cggcacattc
    39541 gattaccgca gaaagttgcg gataaccgac gcctgttttg acgcgagttg tacaaacaga
    39601 acctgggcca atgccaactt taacgatatc ggcacctgag aggataagct cctcacacat
    39661 ttcaccagtc actacgttac cagcacaaat ggttttggtc ggccacgctt cacgcgcttt
    39721 cgcaacgaac tgcacgaagt gttcggaata accattcgcc acgtcaatac aaacgaagtt
    39781 taatgccggg ttcaggtcga gaatctgttt agttttttcg aaatccgcat cagacgtacc
    39841 ggtagaaacc atcacatgtt tcagcacatc agcggaagaa ttgttgataa acgcttgcca
    39901 ctcttcgaca gaatagtgtt tatgcacagc agtcaaaata tcaaaagaag ccagcgcaga
    39961 ggccatagaa aatgtgccta cggtgtccat atttgcggcg ataatcggca cgccggacca
    40021 gctctgacct gaatgtttga aggtgaattg acgttccagt tcaacatcgg aacggctttt
    40081 aagagtggag cgtttagggc ggatgagaac gtctttaaaa cctaacttca gatcttcttc
    40141 aatacgcatg tgcggattcc tggggttaat ggctataagg gtaagagcgc aactccagtg
    40201 acgctatcat acgcactaat caatgcggcg caagactgcg aaattgtctt tttttacgct
    40261 acaatcccat aaatttacct ggtaaatagt gagcgaacgt ttcatcaatt tcgctttcgt
    40321 gcactcattt ttaacgtttt gataatcatg atgaattccc gggaatataa attatgaggt
    40381 atatagttgc cttaacggga ggcattggca gtggcaagag taccgttgcc aatgcgtttg
    40441 ctgatctcgg aattaacgtc attgatgccg atattattgc gcgtcaggtg gttgaaccag
    40501 gtgcacctgc gctacatgcc attgctgatc actttggcgc taacatgatt gctgctgatg
    40561 gaacattgca gcgccgggcc ttgcgcgagc ggatcttcgc caacccggaa gagaaaaact
    40621 ggcttaacgc cctgctgcat ccgctgattc agcaagagac gcaacaccag atccagcaag
    40681 ctacttcccc ctatgtactg tgggttgtgc cattgctggt agaaaactca ctgtataaaa
    40741 aagcgaatcg agtgcttgtg gtggatgtca gcccagaaac gcaacttaag cgcaccatgc
    40801 agcgcgatga tgtaactcgc gagcatgtcg aacaaatcct tgctgctcag gcaacgcgcg
    40861 aagcccgcct tgccgtggca gatgacgtca ttgataataa cggcgcaccg gatgctatcg
    40921 catcggatgt tgcccgcctg cacgcacact atttgcagct tgcgtcgcag tttgtctcac
    40981 aggaaaaacc gtaatgcaga cccaggtcct ttttgaacat ccactaaatg aaaaaatgcg
    41041 tacatggctg cgcattgagt ttttgattca gcaactcacc gttaatttac ccatcgttga
    41101 ccacgctggc gcgctgcatt tcttccgtaa tgtcagtgaa ttactggatg ttttcgagcg
    41161 cggcgaagtc cgcactgagc tgttgaaaga acttgaccgg cagcaacgta aactccagac
    41221 ctggattggc gtgcctggcg tggaccagag ccgtattgaa gcattaattc agcagttaaa
    41281 agcggcgggg agcgtattaa tttccgcgcc gcgtatcggg caatttctgc gtgaagatcg
    41341 tttgattgct ctggtgcgtc agcgactgag catcccaggc ggctgttgca gctttgattt
    41401 acctacattg cacatttggc tgcatctacc ccaggcgcag cgcgacagcc aggtagaaac
    41461 ctggattgcc agcctgaacc cgctcaccca ggcacttacc atggtgctgg atttaattcg
    41521 ccagtcggcc cccttccgta aacaaaccag cctgaatggt ttttatcagg ataacggtgg
    41581 cgatgccgac ttgctgcgcc tgaatctgtc gctcgattca cagctttatc cgcaaatttc
    41641 cggacataag agccgttttg ccattcgttt tatgccgctg gacactgaaa acggacaggt
    41701 accggaacgt ctggatttcg aactggcctg ttgctaagga gtaaaaatgt cagaaactat
    41761 tacggtgaat tgcccaacct gcgggaaaac ggtggtgtgg ggtgaaatca gcccgtttcg
    41821 gccattttgc tccaaacgtt gtcagctgat cgacctcgga gaatgggctg ctgaagaaaa
    41881 acgaatcccc agcagtggcg atctttccga aagcgatgac tggagcgaag aaccaaagca
    41941 gtgacatttg tctgatgccg cacgtaggcc tgataagacg cggacagcgt cgcatcaggc
    42001 atcttgtgca aatgtcggat gcggcgtgaa cgccttatcc gacctacaaa aacaaattta
    42061 tcaatgagtt agaaatccct ttaggcctga taagacgcgc cagcgtcgca tcaggcatcg
    42121 tgtgcgaatg tcggatgcgg cgaaaacgcc ttatctgacc tacagacgtt taagcttcgc
    42181 aattaccggt tcattggctg gcggaaaatc atcggcatta agaccgacca gcgacatcca
    42241 ctcaccgggt tgcccttctt taccccacgg ctccccttcc cagcgttcga ccagccaaaa
    42301 ccacagtgtt atatgcctgt ccgggaattc atattccagt ttttcaaata gcgaaaaatg
    42361 ttggggggta atcccgactt cttcctgaag ttcacgcacc accgcctgtt ccggcgtttc
    42421 acccatttca attttaccgc cgggaaactc cagtttattc gccatgtgcg catctgctgc
    42481 gcgacgcgtt ataaagattt cattgttctc gttgcgaata atacctaccg caatttgcag
    42541 ctttttcatt gtcttaaacc tataaaaaag gcgcagaatc ctgcgccttt tacttcaaca
    42601 gttagctttt attgcaggcg gccatggcac tgcttgtatt ttttaccaga accgcacggg
    42661 caaggatcgt tacgtcctac tttgcgctct ccggtttgcg ccgccagtgc agctgcggct
    42721 gcagagtcgt catcctgatg gctaagctgc tgcatttgcg ctaaacgctc ggcttccata
    42781 cgacgctgtt gttccagctc ctcaacctct tcaggcatac gtacctgaac tttgctcagc
    42841 gtactgataa cttcatattt caacgactcc agcatcgctg caaacatgga gaacgattca
    42901 cgtttgtatt cctgcttcgg atctttctgt gcgtagccac gcaggtggat accctgacgc
    42961 agatagtcca tcgctgccag gtgctctttc cacagggagt caagcgtttg cagcatgacg
    43021 cctttctcga agtgacgcat catctcagca ccaaccactt cttctttacg ctgatacact
    43081 tcgatggact gcgccagaat gcgctcacgc agcgtctctt catgcagttc tggttcttta
    43141 tccagccact cggcaattgg caaatcgagg tcgaaatcgt tcttcagacg ttcctgcagc
    43201 cccggaatat cccacatttc ttccagcgac tgtggtggaa tgtaggcatc aatggtcgct
    43261 ttgaacacat cttcacgaat gctgttaatg gtttcgctca catcgctgac atccaacagt
    43321 tcgttacgct gggagtaaat ggcgcgacgc tgatcgttag ccacgtcatc atattccagc
    43381 agttgcttac gaatgtcgaa gttacggctt tcaactttac gctgggcgtt ggcaatcgct
    43441 ttagtcaccc acgggtgttc aatggcttcg cctggcttca tacccagttt acgcatcatg
    43501 ccggatactc ggtcggaagc aaaaatacgc atcagcgcat cttccatcga caggtagaaa
    43561 cgggaagaac cagcatcccc ctgacgacca gaacgaccgc gcaactggtt atcgatacga
    43621 cgggattcgt gacgctcggt accgatgata tgcaggccac ctgcttccag taccgcatcg
    43681 tgacgtacct gccagtcggc tttaattttt tcaatttgct ctgcggtcgg attttccagc
    43741 gcggcaactt ctgcctgcca gctaccaccg agcacaatat ctgtaccacg acccgccata
    43801 ttggtcgcga tagtcaccgc agccggataa cctgcctgag caacaatcgc cgcttcgttg
    43861 gcgtggaatt tggcgttcag gacgttgtgc ttaataccgg ctttggtcag ttcgtttgac
    43921 accagctccg atttttcgat ggagatagta cccaccagca ccggctggcc tttcgcagta
    43981 cgttctttga tatcttcaat gatcgcctga attttttccg cttcagtcat gtagaccagg
    44041 tccggcagat ctttacgaat cattggacgg ttggtcggaa caacgacggt atccagcttg
    44101 tagattgagc taaattcgaa agcttcggta tcagcagtac cggtcatccc cgccagtttt
    44161 tcatacagac ggaagtagtt ctggaaggtg atcgaagcca gcgtttggtt ttcgttctgg
    44221 atctgcacac cttctttcgc ttccacagcc tggtgcagac catcggacca gcgacggccc
    44281 tgcatggtac gaccggtgtg ttcgtcaacg atgataactt caccatcttt aacgatgtag
    44341 tcgacgtcac gggtaaacag cgcatgagcg cgcagcgccg ccgttacgtg gtgcatcagc
    44401 atgatgttgg ccggagagta cagagactcc ccttcatcca tgatgccctc tttcaccagc
    44461 agttcttcaa tcagcaccag accacgttcg gtcaggttca cctggcgaga tttttcgtcc
    44521 accgagaagt ggccttcgcc ctggaaggtt tcggagtctt ctttttcctg acggatcagg
    44581 tgcggaataa ttttattcac gcgtttatac atttccgagc tgtcttctgc cgggccggaa
    44641 atgatcagcg gtgtacgcgc ttcatcgatc aggatggagt ccacttcgtc caccagcgca
    44701 tagtgcagtt tacgctgtac acgttcttca gggctgaacg ccatgttgtc gcgcaggtag
    44761 tcaaagccgt attcgttgtt cgtaccgtaa gtgatgtcag ctgcgtaagc ttcgcgcttt
    44821 gccggtgctg gcatgcccgg caggttgata ccgacagtca ggccaaggaa ttcaaacagc
    44881 ggacggttgt tttcggcgtc acgttgcgcc aggtagtcgt tgacggtaac tacgtgcacg
    44941 cctttaccgg ttagtgcgtt caggtaagca ggcagcgttg cggtcagggt ttttccttca
    45001 ccggtacgca tttcggcgat gcagcgttcg ttaagaacca taccgccgag taactgaacg
    45061 tcgaagtgac gcataccaaa gacgcgctta cttgcctcac gtaccacggc gaaagcttcc
    45121 gggatcagat tttccagcac ttcgcctttt tccagacgtg cacgaaactc tgcggttttc
    45181 cctttcagtt cttcgtcgga gagtttttcc atctccggtt ccatggcatt gatgatgttg
    45241 accactttgc gcatccggcg cagggtgcga tcgttacgac taccgaaaac tttagttaac
    45301 aatttgatta gcataataaa atctcaaacg ccccgcgttg cggagttaat aaaatgaagt
    45361 aaaggtttat tgttgttagg tgaggcgttg agggccagca cggatgcctt gcgcctggct
    45421 tatccagacg ggcgtgctga attttgcttg tggggtaaaa tgcgcataat caatgcgata
    45481 acccttttca gacggcgtgc cttcctgggt cagcagcgcg ctgagcgtat ccagtaatgc
    45541 aagatgttgc gcctgaagag gcaaagattc ttcagcaacg ggcagtgttt tcggtgccat
    45601 tgcgaaagaa agatgacgga ttaccgtgcg aatggcatgt tgatgccagt aatcaacgga
    45661 atagttcgaa ttcgggcggc gtgtgttcgc ttccagcaag gccaattgac caaagttaac
    45721 tttggctgaa ggctcgtggt tgcgggttgt cgcttttgcg ggcgcgtttg gttcggcggc
    45781 gttgctgagc gcaggcaaac ctaaactcgc cgcaaccatc cctaataaga gatgcggcca
    45841 gaagtagcgt ttaccaaact gtcgccagcg cgtcagtatt ccactcacgt tattgccatc
    45901 ccgatcatat tcaaacgtat ttagcgcaca aatcttatca ttaaagcctg cagtccacag
    45961 cacgaatgaa gataagttgt gcggaaaagt gcttaagaaa acagcgttcg caccgttttt
    46021 tatagctctt ataaaattca aaaaaaaacg actggttcac ctggccggag agagtgccag
    46081 atttgccagt cgaattttat acgacagtat aaatgtcgtt atgccagtac agctgaaggc
    46141 gctttgaagg ccaacggcag ttctgcgtcg tcctggaagg tcacatattc ccaggcttcc
    46201 tgtttcgcca ggacagcctg cagcagtttg ttattcagtg catgaccgga tttataagcg
    46261 gtaaatgcac caataatatt gtgaccacac atgaacaagt caccgatcgc atcgagcatt
    46321 ttgtgacgca caaattcgtc ttcaaaacgc aggccgtctt cgttcagtac gcgataatcg
    46381 tcaacaacga tggcacaatc gaagctgccg cccaggcaca aaccacggga ctgcagatat
    46441 tcgatatcac gcatgaaacc gaacgtacgc gcacggctga tctggcgcat aaacgcatca
    46501 gcggagaagt tcatcgcata gcgctggttg ctggaatcaa tagccggatg gttaaaatcg
    46561 atggtgaaat ccagcgaaaa accattgtac ggcttaaatt cagcccactt atcgccatct
    46621 tcgacacgaa cagtctcttt gatgcgaaca aattttttgg cgcagttcaa ctcgtcgata
    46681 ccggcgtcaa gcagcaggta tacaaacgga gcggcgctgc cgtccatgat cgggatttcc
    46741 ggcgcgttaa cttcgataac aatgttatcg atgcccaagc ccgcgagagc agcattgagg
    46801 tgctctacgg ttgaaatccg tacatcatgc tcgttgacca gacacgtaca gagcatggta
    46861 tcacgcacag atttggcatc ggccgggaaa tctaccggtg gattcaagtc ggtgcgacga
    46921 tagatgaccc cggtgttggc cggcgcaggg cgtaacgtca gggtgacttt cttgccggta
    46981 tgtaaaccga cacccgtcgc ctgaacgata cgtttaagtg tcctttgttt gatcatcgta
    47041 ttatctcgcc aaattaccta tccaaccgaa gtgtactata cattcggcgg gccagtttag
    47101 cacaaagagc ctcgaaaccc aaattccagt caattcttaa tcagcttgct tacgcaggaa
    47161 tgctgggata tccagataat ccggctcttt cgcagtttgc ggcgcattgt cattcacgac
    47221 tttagcaacc ggcttctgct cctgggtcag cggagccatc ccatgctgct ggtagcgatc
    47281 catcactggc tgctgaacct gcttattggt caccagagtg atttcaggac gtttgtccat
    47341 gccgatacct gtcgcaacaa cggttacgcg cagctcgtca ttcatatccg ggtcaagaga
    47401 agtaccgata accacagtcg cgttgtcgga agcaaatgca cggatggtgt tacctaccgt
    47461 ttcgaactca tccagacgca ggtcgaagcc cgccgtgatg ttaaccagca cgccgcgcgc
    47521 gccagacagg tcgatatctt ccagcagcgg agaagagata gccatttcag cagcttcttc
    47581 cgcacggtct tcaccgctcg ccacgccaga acccatcatt gcgtagccca tctcagacat
    47641 tacggtgcgt acgtctgcaa agtccacgtt catcaaaccc ggacgagtaa tcagttcagc
    47701 gataccttgc acagcgcctt tcagtacatc gttcgctgcg ccaaacgcat ccagcaggga
    47761 gataccgcgg cccagaactt tcagcagttt gtcgttcggg atagtgatca gagagtccac
    47821 atgcttggac agttcagtga tcccctgctc cgcgaatgcc atacgcttct tgccttcaaa
    47881 gttgaaaggc ttagtgacga cagcaacggt caggataccc aaatcttttg ccacttcagc
    47941 gacgactggt gctgcacctg taccggtacc accacccata cccgcagcaa taaagaccat
    48001 gtctgcacct tccagcgccg cacgcaatgc atcgcgatcc tcatcagccg cattgcggcc
    48061 aacttctgga ttagcgccag cgcccagtcc tttggtgata ccgctaccga tttgaatcgt
    48121 ctgtccaacc gctgttttac gcagcgcttg tgcatcggta tttaccgcga agaattcaac
    48181 accttcaatg cgctcgcgca ccatgtgttc aacagcatta ccgccgccgc cgccgacgcc
    48241 gatgacttta atcaccgcgt cattggtaag ttccattggt tcaaacatag tttctctccg
    48301 atttgtgcct gtcgcctgag gccgtaatca tcgtcggcct cataaaaatt aaaactcttt
    48361 tcgcagccaa ctattgagtc gcttgatcca cgagccaact gatgctgtaa cacgtttttc
    48421 tacttcagct tcaccgttaa gatgtgactc tttcccatag tgaagcaatc ccaccgccgt
    48481 cgaataatac ggctcctgag cataatccgt taaaccggta atgttcagcg gcgcgccgat
    48541 acgcacttgc gtatgaaaca cgcgctgagc acaggctgca agaccttcga tctgcgctgc
    48601 gccaccggtt aatacaatgc ctgccgccag gtgatgttta accccttgtt ggcgaagctt
    48661 ttcctgcaac tgcaatatct cttcgttgac caggttgagc agctcggtat agcgcggctc
    48721 gatcacctct gccagtgtct gacgttgcag actccgtggc ggacgaccac ctacgctcgg
    48781 cacttccacg ctctcatctt ttccaacgat ggaacccagc gcacaaccgt ggcgaacttt
    48841 aatcgcttcg gcgtcgcttg gcggcgtgcc aaaggcgtaa gcgatatcac tggtcacgac
    48901 attgccagca taaggaatta ccttagtgtg gcgcaatgcc ccaccggtat aaacggcgat
    48961 atccattgta ccaccaccga tatcgacgac gcagacaccc agttcacgtt catcttccgt
    49021 caataccgaa taacttgatg ccagtccggc aaatatcagt tggtcaactt tcagcccaca
    49081 acgttcaacc gctttgacga tgtttttcgc catatcgttg tgacatgtga tcaggtgcac
    49141 ttttgcctgc atccgcacgc ccgaaagtcc taccggattc ttgatccctt cctgatagtc
    49201 aatcgcatac tcttgcggga tcacatgcag cacacgatgc tcatcgcgca cacgcaccga
    49261 tttcgcggta tggacgacgt tttccacatc ttcttgcgtc acttcttctt cagaaatagg
    49321 caccatacca atttcattct ggcagctgat gtgcttacca gaaagcgcca gatataccga
    49381 agagatctga caatctgcca tcaattctgc ctggtcaatg gcgcgttgta cgcacttgac
    49441 cacggattcg aggtcgttca ccccgccttt atccatacca cgcgacgggc agctgcccac
    49501 gccaatgata ttgaccatac cgtcgggcag aacttcccct actaaagcgg caaccttcgc
    49561 ggtaccaatc tccagtccta ctaccagttt tctgtccgtc gccttgatca ttgttgttct
    49621 gcctgtgcct gattttgttg ctgagtagat tcctctggcg gcaagggcgc ccagcctact
    49681 gccgctccag agtcataacg caaatcaacg tagctaatcc gtttgccatc ggtttgcgcc
    49741 tgctgctgta aaaccggata aagttctaca aagcgagcca aacgtttcat cgtatcgccc
    49801 cggccaagat tgagcttaat atcgttattc agcgtcaact gccaggaacg ccgcgcggtc
    49861 atcgccgctt ccttcagagt aaatctgtcc tttgccagca tctgccccat ttcgcgatag
    49921 ccctgcaaca cttcattggc gctgccttcc gggccataca gcattggaag cacctgcttg
    49981 ctggtgcgtt ctggcggcac gctgaaggta tttccttccg cgtctaccat atgttgatca
    50041 ttccaccgcg caatcggcac atattcaacc agatgaatct tcaattcatc aggccactgc
    50101 tttctgacgc tcacctgctt aatccacggc aggcgttgtt ctatttgcgt ctggatgatg
    50161 ttgacatcct gggtcataaa ggtacccggc tcacccaatg ccaggatcga ctgccggata
    50221 tcgtcattac gtgtgtaatg gcgttcaccg gtcaacacca gctttgagag cggcaggcgt
    50281 tgcgcatctt ccatccagcc caacacgacc cagccgctca ccaacactgt cgttaaaacg
    50341 gtcagcagga aaaggatccc cgccagacgc gttccattat tgcggcgaga agaaacctct
    50401 tcttcgctgt ttcgcgtgtt cagagcagcc tgcgacatat tagtccgcca gttccagaat
    50461 tcgtactacc aactgcgaga agctcatacc tgcctgacgt gccgccatcg gcaccaggct
    50521 gtggctggtc atacccggtg aggtattggc ttccagcaga taaaactgtc catcgctgtc
    50581 cagcataacg tcaatacgtc cccatccttt gcaacctaac gtcgtccatg ctttcagcac
    50641 taatgcctgc aaattggcct cttgtgacgc ttccagacct gcggggcaga aatactgtgt
    50701 ctcatcagag agatacttcg cctcataatc atagaaggtt ccggacggtt gaatacgtat
    50761 tgacggtaaa atttcttcac cgagtatcgc aaccgtgaac tccggcccac ttagccattt
    50821 ttcaatcaat acttcttcat cgtgctgaaa tgccaatctt aatgcatctt gtagagcatt
    50881 ttctgctact acttttgaca ttcccacact ggaaccttcg cggctcggct taacgataac
    50941 cggcaaaccc agagcagaaa tttctgctaa ctgcttatcg ctcaggcctt tttcaaactc
    51001 tgcgcgggtt aacgctaccc acggcgcgac cggtaaaccg gcaccttgcc atagaagttt
    51061 gctgcgtagt ttatccattg aaagcgcaga tgccatcact ccgcttccgg tataaggcaa
    51121 gcccatcagc tcgagcatcc cctgcagcgt accatcttca ccgccgcgac cgtgtagcgc
    51181 gataaacact ttctgaaagc ccatcgactt cagttgcgtc acgtcgactt ctttcgggtc
    51241 gacaggatac gcgtcaatac cgccttcacg cagtccggct aacaccgctg cgccagaatt
    51301 cagagaaact tcccgctcag cggaggtccc acccaacagg accgcgattt tatcagtcat
    51361 gttgttcttc ctccggagtt tgcggcttca gtttgatttc agctaaagaa cgggcaattt
    51421 ttccaatatt accagccccc tgaacgagaa tcaggtcgtt accggttaat accggtgcca
    51481 gcatctcggc tacccgcgcc ggatccggca ccagaatggg atcaattttc ccacgtccac
    51541 gaattgtgcg acacagcgaa cggctgtccg ctcccggaat tggcgcttcg ccagccggat
    51601 acacttccag catcaacagg gtatcaacct gcgtcagcac attggcgaaa tcatcataca
    51661 ggtcgcgcgt acgggtaaaa cggtgcggct gaaacagcat taccaggttt ttatccggcc
    51721 agcctgcgcg cgccgcttta atggtggcgt ccacttccgt cgggtggtgg ccgtagtcat
    51781 cgaccagcat tgccgtaccg cttttaccat tcactggctc cagcgggaat tcaccgagga
    51841 aatcaaaacg gcgaccagtc ccctggaagc tttcaagcgc ccgcaaaata gcctcgtcgt
    51901 caatgccctc ttccgtagca accgcaaccg cagctgcggc gttcagcgcg ttatgacgac
    51961 ctggcgcatt cagggtgacg cgcatcggct ctttgtcctg gcgcagcagc gtaaagtgcc
    52021 cctgcgggcc aatctgctga taatcttcta cacgcacgtc ggcatcttcg ctgaagccgt
    52081 aagtcgtggt ctgacgcccc actcgcggta acaattcgcg gatcaccgga tcatcaacac
    52141 acatcaccgc acgaccgtaa aacggcaggt tgtgcagaaa attaataaaa gtctgtttta
    52201 aattctcaaa gtcgccctgg taggtatcca tgtggtcggc ttcgatattg gtgacaatcg
    52261 ccaccatcgg ttgcagatgc aggaacgatg catcactctc atctgcttcg gcaatcaggt
    52321 accgaccatg ccccaaacgc gcatgaaccc ccgccgcttt taccagcccg ccgttaacga
    52381 aggttgggtc gagccccgct tctgcgtaga tgctggaaac catcgcggtg gttgtcgttt
    52441 tgccgtgcgt tccggcaatg gcgatgccat gacgaaaacg cattaactca gccagcattt
    52501 cggcacgacg gatcaccgga atacgcgctt catgagcggc gacaatttcc gggttatcgg
    52561 cagaaatcgc gctggaaaca acgaccacgc tggcatcacg tacgttttcc gggcgatggt
    52621 tgaaataaat cgtcgcaccc agattcatta actgctgcgt gaccggattt ggcgctaaat
    52681 cggaaccact gatctgataa ccttcattgg ccagaacttc ggcaataccg cccataccgg
    52741 caccaccaat gccgacaaaa tgtatgtgcc gaacgcgacg catttcgggc acgatggaac
    52801 gcagttttgc caattgttgt gtattcattc tttacgccat taacttctta aattcatacg
    52861 atgcaaaagg catcgctaca attacgcccg ggcaacccgg ctcacttcat ttgccactcg
    52921 ctcggtggca tccggaatgg atgcagcgcg ggcgcgttct gccatggtta ataaggtttc
    52981 tcgcgaccac ccggccaggg tgttggcgac agcatccacg ctaagctgtg gctgctcgat
    53041 aattttggct gcgcccgctt tttccagcgg tagcgcattc cagtattgct ggcggtcttt
    53101 atgttgaaac ggcacaaaca acgccggtag tcctgccgcg gcgatttcac tcaccgttaa
    53161 cgcaccggag cggcaaacga cgacatccgc ccacgcatac gccgccgcca tatcatcaat
    53221 aaattccgtc actttatgct gcggttgccc cgcttcggca tacgcctgtt caacggattg
    53281 ttgcgaacct ttgccgctct gatgccagat agtgactgaa tcacccagtt tcgcagcaac
    53341 ctgcggcatt gtctggttaa gaatgcgtgc gccctgagaa ccacccacta ccagcacacg
    53401 aaccggacct tcacgtccag ccaaacgttg ctgcggcaac ggcagcgcca acacatcggt
    53461 acgcaccggg ttacccacta cttccgcatt agggaaagca cctggaaacg cctgcatcac
    53521 tttggtggca atcttcgcca gccatttatt ggttaagccc gcaataccgt tttgttcatg
    53581 aagtacaacc ggaatgccta acgaccacgc ggccagacca cctggacctg acacgtagcc
    53641 tcccataccg agcaccacgt caggtttgta cgctttcata atcgcccgcg cctgacgcca
    53701 ggcgttgaag atacgcagcg gggcagctat cagtgctttt ataccttttc cacgcagacc
    53761 agagatacga atgaaatcaa tttcgatgcc atgttttggc actaagtccg cttccatacg
    53821 gtcggcagtc cccagccagc gaacttgcca accctgagcc attagatggt gcgcaaccgc
    53881 cagtcccggg aatacatgtc caccggttcc gcctgccatc accattaatc gctttccttg
    53941 accactcatc gtgaacctcg tacaaacgcc tgcgctttct ccagacgcgt ttcataatca
    54001 atacgcaaca gcatcatgat ggctgtcgac ataatcagta agctcgaacc accgtaactg
    54061 atcagcggca atgtcagacc tttggtcggt aacatccccg ccgccgcgcc tacgttaacc
    54121 agcgcctgga agctaaacca gatgccaata gaacaggcga gaaaaccgga aaaacggtgg
    54181 tcaatttcta atgctttacg gccaatcgac atcgcgcgaa aagcgacgaa gaataccatt
    54241 aaaagtgcca gcaccacacc gacatacccc agttcttcgc cgataatggc gaaaataaag
    54301 tcagtgtgcg cttccggcag atactccagt ttttgtaccg agttacctaa accttgcccc
    54361 caaagttcgc cgcgaccaaa cgccatcagc gattgcgtta actgatagcc gctgccaaag
    54421 ggatcttccc acgggttcca gaatgcggta acacggcgga tacggtacgg ttcggcgagt
    54481 atcagcaaca caaccgctga aatgcccata ccgataatgg caatgaactg ccacaatttc
    54541 gctcccgcca ggaacaacat cgccagcgta gtcacaaaca acaccaccac cgtaccaagg
    54601 tctggctgtg ccagcagtaa cactgccaac accagaatca cgcccatcgg tttcaggaag
    54661 ccgcgcaggt tattacgtac ttcgtcgcct ttacgcacca gatagttggc gatatagcaa
    54721 aacagcgaca gttttgtcag ctccgcaggc tggatacgca gcaaaccgag atcgatccaa
    54781 cgcgatgccc ctttaaccga gctacccact accaggacga tcatcagcag gatgatagat
    54841 ccgagcagca tcgtggcact gtagcgttgc cagaactcca tcggcagacg cagcgtaatg
    54901 atcgccagaa taaacgccaa aatcagatag acaccatcac gcttcgcgaa gaagaacgga
    54961 tcgttggtta agcgttgccc tatgggcatt gacgccgagg tcaccatgat aaagccaatc
    55021 gccgcgaggc cgaaggtcag ccacagtaag gtgcgatcgt acatgatcag gctgtcggta
    55081 tctttttccc gcgagcccat cacccagccc tttagcgccg tggagatcca gaccaggata
    55141 ctgaatcctg gcaggcgcgg cattttcagg cgagggagag ataaacgcat caacctaact
    55201 ccttcgccag acgggcaaac tcattgcctc gttgttcaaa gttcttgaac tgatcaaggc
    55261 tggcacaggc tggggagagc agaaccatat cgcccggctg aacacgcgga gccagcaagc
    55321 gcatcgcctg ttccatagtt tcggtttgtt ctgccacttc cgggcgtagc gccgccagct
    55381 gcgcgccgtc acgaccgaaa caatacagac gtacgttatc gccattcagg taacgcgcca
    55441 gtgggctaaa gtccgccgat ttaccatcgc cacccagcaa caaatgcagt gtgccgtcta
    55501 cgtgcaggcc attcagcgcc gcttccgtac tgccgacgtt ggtcgctttc gaatcgttaa
    55561 tccaacgtac gccgttatgc tccagcacaa cttcaaagcg atgcggcaga ccagtgaatg
    55621 tggttaacgc tttcaggctg ctggcacgcg gtaaccctgc agcatctgcc agcgccagcg
    55681 ccgccagcgc attggtgtag ttatgctgcc cggaaagttt catctctttc acattcagca
    55741 ctttctcgcc tttaacccgc agccaggttt cgccctgctg atgattcagg tgatagtcac
    55801 ccatgttgac gccaaagctg acgcagcgtt catccgcacc gcgaatcggc attgttaagg
    55861 catcatcagc attaaccacg caaactttcg cgttttcgta aatgcgcagt tttgctgcac
    55921 gatactgttg taaaccaaac ggatagcgat ccatatgatc ttcagtcacg ttcagaatgg
    55981 tcgctgctac cgcctgtaag ctggaggtgg tttccagctg gaagctcgac agttccagca
    56041 cgtacagttc acactcatca tccagtagca tcaacgcagg caggccaata ttgccaccca
    56101 caccaacgtt aacccccgcc gctttcgcca tttcacccac tagcgtggtg accgtgcttt
    56161 tgccgttaga accggtaatc gccacaatcg gtgcttgtgc ttcgcgacag aacagctcga
    56221 tatcgccaac gatttcgatt ccggcatcag cggcagcgct taaggatgga tgcgccagtg
    56281 caataccggg actggcgaca atcagatctg ccgccatcag ccattcatca ttcagactgc
    56341 ccgtgtggcg ttctacggct tcgggtaatt tatccaggcc aggcggtgtc atacgcgtat
    56401 ccataacgcg cggcgtcaca ccgcgagcga ggaaaaagtc cacgcaggaa agcccggtga
    56461 ggcccaggcc gataatgacg acatttttac cctgataatc agccatgatt aacgtacctt
    56521 cagcgttgcc agaccaatca gaaccagcat cagcgaaata atccagaaac gcacaatgac
    56581 gcgcggttcc ggccagcctt tcagttcata gtggtgatga atcggtgcca tgcggaaaat
    56641 acgttgtccg cgcagtttaa aggagccgac ctgcaggatg acagaaagcg tttctaccac
    56701 gaacacgccc cccataatca ccagcaggaa ttcctgacgt agcagtacgg cgataatgcc
    56761 taacgcacca cctaacgcca gcgaacctac atcgcccata aagacctgcg ccggataggt
    56821 gttaaaccac aggaagccca gtcctgcccc gactatcgcg gtacagacaa taaccagttc
    56881 cccggcgtgt cgcagatacg gtatatgcaa gtagctggca aagttcatat tgccggtcgc
    56941 ccacgccacc agcgcaaaac caccggcgac aaatacggtc ggcataattg ccaggccgtc
    57001 gagaccatcg gtcaggttta ccgcgttgcc agtacccaca atgacgaagt aagccagcag
    57061 aatgtagaac agccccagct gcggcatcac atctttaaag aatgggacca ccagctgcgt
    57121 tgcgggcgtg tctttgccgg caaggtacag ggcgaaggcg acacccagcg caatgaccga
    57181 catccagaaa tacttccaac gagcgatcaa ccctttggtg tctttacgca ccactttgcg
    57241 ataatcatca acaaagccaa taacaccgta acctaccagc accaccaaca cgcaccagac
    57301 gtacggattg gacgggtaag cccacagcag tacggagatc acaatcgccg tcaggatcat
    57361 aatcccgccc atggtcggcg taccgcgctt gctgaagtgt gattcaggac cgtcgttacg
    57421 caccacctga ccaaaggaaa gtttttgcaa atgagcaatc atacgcgggc ccatccacaa
    57481 tgagatgaac agcgcggtca gcaggctgac gatggcgcga aacgtcagat aggaaaagac
    57541 gttaaagccg gaataatatt tgaccaaatg ttcggccagc caaactaaca tgtcccattc
    57601 tcctgtaaag cgcgtactac ctcttccatg gcggcactac gtgaaccctt aactaaaatc
    57661 gtaattacct gttgctcagc aatcagtaat ttaagacgcg taattaacgc agttttatca
    57721 gcaaaatgtt cgccaacgcc gctggcggtg ctgatagcat ggctttgttt acccacgctt
    57781 aacacgcggt caataccagc agcttttgcc gcctcgccca cctgtacatg gcaggcttcg
    57841 ctttcagcgc ccagttccgc catatcgccc accaccagca cgcggtagcc cggcatttca
    57901 gccagtacct ggactgctgc agtcattgaa ccgacattgg cgttgtagga gtcgtcgagc
    57961 agcaactggt tttctgccag ttggatgggg aacagacggc ctggaacagc tttcagattt
    58021 gccagccccg ctttgatagc atcaagcgtt gcgcccacgg acatggagag cgcagcggct
    58081 gccagcgcat tcgcaatatt gtgacgcccc ggcaacggca gcagaacatc gacgctaccg
    58141 gttggggttt gtagggtaaa ttccgtaccg tgcgaggtca catggatatt ggtggcggtg
    58201 aaatcgctgt tggcggcatt gggtgagaaa cgccacactt tgcgtgagcc aattacgctc
    58261 tgccagttca gccagtcgtt gttgtcggcg ttcataatgg cgataccgtt ttccggcagg
    58321 ccgctaaaga tttcaccttt cgctttcgcg acacccgcaa gcgagccaaa accttccaga
    58381 tgcgccgctg ccaggttgtt gaccagcgca gcttccgggc gagtcagact cacagtccag
    58441 gctatttcgc cctgatggtt cgcgccaagt tcaataactg cgtaatcgta ttccggcgtt
    58501 aagcgcaaca gcgtcatcgg tacaccgatg tcgttgttga gattgcctgc cgtataaagc
    58561 gtgttgccgc actggcttaa aatcgccgcc gtcatctctt taacggaggt tttgccggag
    58621 gaccccgtca gagcaaccac gcgcgccgga acttgctggc gaacccatgc agccagttca
    58681 ccaaacgcca gacgcgtatc cttgacgatt aactgcggca ggtcgatgtc cagcggacgg
    58741 ctaaccagta gtgcgcctgc gccgccagct ttcgcctggt cggcaaaatc atgagcatcg
    58801 aaacgttcgc ctttcagggc aacaaacagg cagcccggcg tcagttttcg ggtatcagtg
    58861 gttacagcat caagggtgat atctgcacct tgcaggtcac cgttgagaat gtcggtaagt
    58921 tggctaaggg ttacgctaat catgcaatca cccccagcag acgcgccacc gtgacgcgat
    58981 cggagtagtc cagacgctga ttgccaacaa tctggtaatc ttcatggcct ttgcccgcga
    59041 ccagcaccac atcgttctct ttagcctgca taacggcgca agtcaccgct tcagcacggc
    59101 cttccatcac tttggcatgt ccggcatcta acattcccgc cagaatatcg ttgatgatgg
    59161 cacgcggttc ttcggtacgc gggttatcgt ccgtcaccac cgccacgtca gcaaactctt
    59221 cggcaattgc gcccatcagt ggacgcttac ctttatcgcg atcgccacca cagccaaaga
    59281 cgcaccacag cttgcccgca cagtgcagac gcgccgcctg taaggctttt tccagcgcat
    59341 ccggcgtatg cgcgtaatcc accaccaccg tcggtttgcc tggcgcagtg aacacttcca
    59401 tacgtccgca aaccggttgc agacgcgcgg cggttttcaa cagatcagcc aatggatagc
    59461 cgagtgccaa cagtgtcgcc agcgcgagca gcaggttgct gacgttaaaa gcgcccatca
    59521 gatggctttc aatttcgcca tcgccccaac ttgagctaaa gcgaatcgtc gcaccgctgt
    59581 cgtgatagtt cacgtcgatc gcttttaacc agcgtccgtg acagttcgga ttgatatgat
    59641 cttccattga taccgcaaca gcgtccggca gttttgccag ccagcggcgg cccacttcat
    59701 cgtcggcgtt aataatcgcc tgaccgcaat gatgttcaga ataaagcagc catttcgcag
    59761 cttcgtagtg ttccatatca ccatgataat caaggtgatc gcggcttaag ttggtaaaga
    59821 ccgacgccgc aaatttcaat gccgccacac ggtgctgtac cagcccgtgg gaggaaactt
    59881 ccattgcgca aaaagtcgcg ccctgatcca ccagccccgc cagctcatgc tgaacatcga
    59941 ctgcggaacc ggtagtattt tctgtcggga tcactttccc aagcagaccg ttaccaacgg
    60001 tgcccattac cgcgctggtt tcgccaagca gttggctcca ctgcgccagc agctgggtag
    60061 tcgtggtttt gccgttggtg cccgttacgc ctacgagacg taaattgtca gagggttcat
    60121 ggtaaaagcg gcccgccagt gcagataaac gctcattgag ctggctgaga tagatgaccg
    60181 gtacgccgtg catttcacgg atttcaccgt cggtcgcctc atctttcgcc tctgcaataa
    60241 tggcagccac accttgcgct atcgcctgcg ggatatatcg acgcccgtcc gcctgatgac
    60301 ctactacagc tacaaagaga tcgcccgccg cagccacacg gctgtcgagt gtcatctctc
    60361 gcagtgctcg cgaaggtgcg tctggcaccc acggagcaag aaggtcgcgc aaattacgat
    60421 ctgccacctg tcccctcgcc ttgattaatc acaaattcat ttttatcgcc cgttgtcagc
    60481 gcatccggct cgatgttcat ggtacgcaat acgccgccca tgatggcacc aaagaccggc
    60541 gcggaaacgg cgccgccgta gtatttaccc gcctgcggat cgttgataac aacaaccagc
    60601 gcgaagcgcg gctgactcgc aggcgcaacg cctgcggtat aagcaatata tttattgatg
    60661 tagcgaccgt ccggcccgac ctttttcgcg gtaccggttt taatggcgat acgatagcct
    60721 ttaatcgccg ccttcacgcc gccgccgccc ggtagcgcca cgctttccat catatgcacc
    60781 acggtgcgga caatggattc cgggaagaca cgttcaccgg gaaccggggg gtcaactttg
    60841 gtaatcgaca gtgggcgata aatgccgtag ctgccgatag ttgcgtagac tcgcgctaac
    60901 tgtaacggtg ttaccattag cccgtagccg aaagagaagg tggccctctc tatgtcagac
    60961 caccgttgtt tttgaggata taagccactg cgttctccga ccaaccccaa attggtcgct
    61021 tttcccagtc caaaacgtga gtaagtatct actaacgctg aggacggcat cgctaacgcc
    61081 agcttggaaa caccgacgtt actcgacttc tgtaataccc cggtcagggt taattcgctg
    61141 tagcgtgcca cgtctttgat ttcgtggccg tttattcgat aaggaacggt attgagtacc
    61201 gagttttccc gcaccacgcc acgttgcaac gcggtcatca ccaccatcgg tttaaccgtt
    61261 gagcccggtt caaacacgtc ggtgatggta cggttacgca tcgcctcttt cggcgtgcca
    61321 ctcagattgt tagggttgta tgatgggctg ttagccatcg ccagcacttc accggtgttg
    61381 acatccacca gcacggcgct accagattca gccttgttaa aggccaccgc attgttcagt
    61441 tcgcgataaa ccagcgcctg caggcgttca tcaatactca gcgccaggtt gtgcgcagcc
    61501 tggctgtcag tagaagaaat atcttcaatt acgcgaccat agcggtcttt acgcacaatg
    61561 cgctcacccg gctgcccggt aagccattta tcgaaactct tctcaacgcc ctcaatccct
    61621 tgactatcga cgttagtaaa gccaatgagg tgagcagtca cttcgccgga tggataataa
    61681 cggcgagatt cttcacgcag atgaatcccc ggcagtttca gttttttgat gtagtccgcc
    61741 atgtcagggt ttacctgacg cgccagataa ataaagcgcc ctttcgggtt ggcgttaatg
    61801 cgggcagaaa gctgatccag cggaatattg agcgcgttag ccagcgcctt ccagcggtca
    61861 ccgacgctga taccaccagc gtcatgcact tctttcgggt cagcccaaat cgcttttacc
    61921 ggcacgctca ccgctaacgg gcgaccagaa cggtcagtaa tcatgccgcg ggaggtggaa
    61981 acttgctgaa cgcgaagaga acgcatgtcg ccctctttca ccagcatatc cggggagata
    62041 acttgtaacc acgctacgcg tccgagcaga aaagccagcg ccaggagaat acagccgcat
    62101 aacaacgcaa aacgccaact gataaagttg gcatgttctt cctgacgttt tggtttctgc
    62161 gttttcgccg ctgctttcat gcgtcgcgtt tatccttatt tttgcactac gatattttct
    62221 tgtgacggat caacatgctg catttgcagc ttttccgtgg cgatcctttc cacccggcta
    62281 tggtcgccga gcgcattctc ttcaaggatc aggttgcgcc attcaatgtc taaagcatct
    62341 cgctccagca ccagttgttc gcgctgagcg gtcagtaaac gggtatggtg cgccgtggtt
    62401 accacagtca ccgccgtcaa aataatgcaa atgaacaggc agagtggcag cttcccaaat
    62461 cgcaaaagat cgtcaccgat aacaccaggc aatgcatggc gctcgtggct tcccatcgat
    62521 cctttaactt tgcttagagc ttctgtcact ctgctgatca tgcattcgtc ctctctgcaa
    62581 tacgcagaac tgaactacgg gcacgagggt tctcagccac ctcttcttcg cccggcatta
    62641 acttgcctag tgctcgcagc tgacggccac ccagtttttt gagctgctct tcagtcatcg
    62701 gtaaccctgc cggaacttgc ggaccgcggc tgttttcacg cataaaacgt ttcacaatac
    62761 ggtcttccag cgagtggaag ctgatgatcg aaagccgccc acccggggcc agcacgttga
    62821 gcgagctttt tagcgcctgc tctatctcct ccagttcact gtttacccaa atgcgcaccg
    62881 cctggaaggt acgggtcgcg ggatgtttaa acttatcttt caccggcgtt gcagcagcca
    62941 cgacttccgc cagttctttg gtgcgggtca tcggctgttc gcggttacgc tcgacaatgg
    63001 cgcgggcaat gcgtttggca aaacgctctt caccataggt tttcaatacc caggcgatat
    63061 cggcttcttc tgcggtttgt agccattcag cggctgactg cccacgggtt gggtccatac
    63121 gcatgtccag cggaccatcg cgcataaagg aaaagccacg ttcagcatca tcaagttgcg
    63181 gtgaagagac gccaagatcg aggagaatgc cgtcgatctt gccgataaga tcgcgctcgg
    63241 caacgtattc gcccagcgcg gagaaaggtc cgtggatgat ggagaagcgc ggatcatcaa
    63301 tagtcttcgc aacggcgata gcctgcgggt cgcgatcgat cgccagcaaa cgcccctctt
    63361 cgccaagctg cgagaggatc agacgtgagt gaccaccgcg accaaaagtc ccatcaatgt
    63421 agatgccatc aggacggata ttgaggccat taacggcttc atccagcagc accgtagtat
    63481 gtttatagtt ttccatcatt ttatagagac aagtcctgca gtcgctccga taagtctccg
    63541 gtagccaact gctctgcgtc gatatcttcc ttgacctgtt gatgccaggt tgtttcatcc
    63601 cacagctcaa acttgttgaa ctgtccaacc agcatcactt cttttgtcag cccggcatgt
    63661 tgccgcagta ctggcgcgat taacaatcga cctgcgccat ccatctgaca ttcgctggca
    63721 tgacctaaca gtaggcgctg cacacggcgc tcaaccgggt tcatgctcga cagacgcgat
    63781 aatttttgct cgataatttc ccattcaggc agggggtaaa gcagcaggca cgggtgataa
    63841 atgtcaatgg tgcaaaccat ttgaccggca gcgttctcaa gcagctgttc ccgataacgg
    63901 gtaggcactg ataagcgccc tttgctgtcg agattgacta acgttgctcc ccggaacatg
    63961 ccagcctcac cccttattcc cactttgccc cacaatttcc cactgaaagg agtttacgga
    64021 gctgaggaaa agcttgtcaa gccagtcaca aggcataccg aggtaaaaaa cccgatgttt
    64081 acggctaata tcagcgttgt ttattttacg tccaacgtgc gaagcaaatt aacgttatga
    64141 atagctgtaa gaaaaaatcc ctcatcgtca tcaccgtttt aaaatgactc actattttcc
    64201 acagcaaata taaagtgtca gtttgcgacg cgagcggcat tttaggacat atcttccccg
    64261 gttaacagtc cttgttacgt ctgtgtggcg cttgatgcca gcgggtttgc gcaaaagcaa
    64321 agaaaagtgt ttgttaaatc ggcaattcat cgccgcatgt aacaaaataa tgcaaaaacg
    64381 cgctgtcgat atcacttaat tattgtgaat ttcagctggt gagttaatta acgggcgggt
    64441 ttaaaagcat ttatcaataa tagtcaggaa tagtcttatt tactttaagc atattgatgt
    64501 ccagtcccgt actctacgcg ccagagggaa attcacctgg cgcgtatttt tgttcgcggc
    64561 ttagctacgg ctgagcacgc cgcggcgata gagattacgt ttaatgcgcg ttaaaccagg
    64621 ttttggctta cgcggttcgt ccaggcttgc caggacaatc tccagcacac gctctgcgac
    64681 atcgcggtga cgttgagcca ctgccagcac cggacactgt aagaagtcga gcagttcgtt
    64741 atcgccaaag gtggcaattg ccaggtcaga aggcagtttg ccgtcgcgac gcagcgtgac
    64801 atccatcact ccttgcaaca acgcaaacga cgttgtgaac agcgcctgcg gcatcggatg
    64861 cgtttccagc catttttcga ataactgggc agccgcctcc cgctcatagc tgttggcata
    64921 caggaaatgc acttcgcgcg gatcatcttt ccaggcagta cggaaacctt gttcacgcag
    64981 gaagctgaca gaaagctccg gtagcgcacc aagataaagc accgtctcgg cgggaaactt
    65041 acgtaactct tccgccagca tttcggcatc atcctgatcg gcaccaacca cgctggtgaa
    65101 gtgttcacga tcgagggcgc ggtccagcgc gacaatcggg aacgggtcgt tagcccagcg
    65161 ttgataaaaa ggatgctcag gaggcaacga cgtcgaaaca ataatggcat caacctgacg
    65221 ctgtaaaagg tgctcaatgc accgcatttc gttgtctggc tgatcttctg agcaggcaat
    65281 cagcagttga taaccccgtt gccgcgcctg gcgttcaaga tagttagcga tgcgggtata
    65341 gctggtgttc tccagatcgg ggatcacaag accaatagaa cgtgtgcgtc cagcacgaag
    65401 cccagctgcc acggcgttcg ggtggtaatt gtgctcacgc accacagcca tgactttttc
    65461 aacggttttg tcgctcacac ggtattgctt cgctttgccg ttaataacat agcttgcagt
    65521 ggtccgcgac actcccgcca gccgagcgat ttcatccagt ttcacaattg ccccttgcgt
    65581 aaaatgtaaa aaccatagcc attgtactgg tatgggttaa attcattaac atctaagcgc
    65641 agaaaattaa ctgcggcaac tgcttttatt ccaggttccc actgatttcg caaaaaaagc
    65701 ccaacgtgac atgttgggct gtaaattgcg cattgagatc attctcaacg cattatttta
    65761 tcgccgcgcg aaagtccgac cacaccagag cgagcaacct ccacaatttt cgccacatcg
    65821 cgaatcgatg ctaaaaatgc atcaagctta ccgctggtgc ctgctaattg aacggtataa
    65881 agcgagggtg tgacatcgat aatttgccca cggaatattt ccgtattacg tttcacttcg
    65941 tcacgcccgt aaccgctggc ctgaattttc accagcatga tttcccgctc aacatgcgcg
    66001 ccctgcccca actcactcac gcgcaagaca tcgaccagtt tgtgtaattg cttttcgatc
    66061 tgctcaagta ctttttcatc gcccacggtc tggatggtca tacgcgataa tgtcggatcg
    66121 tcggttggcg caacggtcag gctttcaatg ttgtagccac gctgggaaaa aaggccaatc
    66181 acgcgggata acgcgcctga ttcattttcg agtaagactg ataatatccg gcgcataatc
    66241 aggttctctc cgttttgctt aaccacattt catccattcc gcccccgcga atctgcatcg
    66301 ggtagacgtg ctcgctgcca tcgacggtaa catcaacaaa caccaggcga ttattgcgca
    66361 cctgttccag cgcctcgcta agtttgcttt ccagctcatg cggatgagaa atctggatcc
    66421 cgacatgccc ataggcttcc gccagacgga cgaaatcggg tagcgattgc atataagatt
    66481 gtgaatgacg gccggaatag atcatgtcct gccactgctt caccatcccc agatagcggt
    66541 tattgagatt caccaccagt acgggcaact cgtattgcaa cgcggtagac agttcctgga
    66601 tgttcatctg aatactgccg tcgccagtga cgcaaaccac ggtttcttct ggcaacgcca
    66661 ttttgacgcc cagtgccgca ggtaaaccaa aacccatcgt gccgaggcca ccggaattga
    66721 tccagcgacg cggtttgtcg aatggataat aaagtgcagc aaacatctgg tgctgcccga
    66781 catcggacgt cacgtaagcg tctcccttcg tcaaccgcca aagagtctcg atcaccgcct
    66841 gcggtttaat cttttcactg tgagtgtcat atttcaggca ctgacgagcg cgccactgtt
    66901 caatttgctg ccaccagtcg cggatctcat ccagtggttg atgggcggat tcttgcgaca
    66961 agagttcaag catttgttcg aggacctggc gagcatcccc cacaatcggg atatccgcag
    67021 tcacggtttt agaaatggaa gtaggatcaa tatcgatatg cagaacagtg gcatttgggc
    67081 agtactttgc cagattgttc gtcgttcggt catcaaatcg taccccgacg gcgaaaatca
    67141 catccgcgtt atgcatcgtc atattggctt cgtaggtacc gtgcattccc agcatgccca
    67201 gtgcctgacg atgcgttgcc ggaaacgccc ccagccccat caatgagcaa acaacgggca
    67261 gattcaacgc ctccaccgtt tctttcaact gctgatggca gcccgccgtg attgccccac
    67321 cgcctacgta gacaaccggt ttttttgccg ctaccagcgt ttgcagagca cgcttaattt
    67381 gccctttatg tccggtagta gtgggattgt aagaacgcat actgaccgac tccggccaga
    67441 catagggtaa tttgttcgcc ggattaagaa tatctttcgg taaatcaacg actactggtc
    67501 ctgggcgacc acttgccgcc agccagaaag cctttttcag cacctgcgga atgtcttccg
    67561 tttgcttaac cagaaaactg tgtttaacca ccggtcgcga aatccccacc atgtcgcact
    67621 cctgaaaggc atcgtaacct atcaacgagg tcgctacctg cccggaaagg acaactaatg
    67681 gaatggaatc catataagcg gtggcgatgc cagtaatcgc attggtcgcc cctggacccg
    67741 acgttaccag cacgacgccg acttccccgg tcgcgcgcgc caggccatcg gccatatgca
    67801 ccgccgcctg ctcatgacga actaatacat gatcaatacc acccacggta tgcaatgcat
    67861 cataaatatc aaggactgcg cctccgggat aaccgaatat ttgtttaacg ccctgatcga
    67921 taagcgatcg gacgaccatc tcggctccag acaacatctc catggcctgc ctcactgttt
    67981 gacggaaaaa atgtgtaaaa cacattaacc gtccgatctt gcttaagcaa ttggcagcca
    68041 gagacataaa cacggggtaa taagaataaa caggaggaaa ggtgaaaaga aacgataaaa
    68101 tcctccatta cagaggatta aattgataat aaatcggctg aatcccacaa cttacagcaa
    68161 tttctctatt tttttaatta atcctaaaat agagagccca cacattcaga ataaaattct
    68221 acattcaata aaaaatgcag aataaaccag acattcatgt ctgacctatt ctgcaatcag
    68281 ttagcgtttg caaattgaga ctaattgctc ttccatccac tgatggcctt tatcgcgccc
    68341 ggcagcttca tgccaggaga gataacaggt tctgctgttt tgttttaacg gcagcggtaa
    68401 tacctgtaat tctaaggatt cagcgaactc ttcagccagc caacgcggcg caatagcgac
    68461 caaatgcgtt tgcgacacca cgctaagtac gctcatcatt gccatgccct gatacgcgat
    68521 actggcttgc ttatctaccg tgtcatacca aggttgacta aatgacgcga aacgatcgag
    68581 cgaaaccgcc gcatgttgtt cgttataaac atcatgtttc agtaacgggc ccttaattgt
    68641 tggatgattt ttgctggcta ccagcaccat ttcatcttta aataatggta cgctggtaaa
    68701 ttcaggacga tggaagtctt cataactaat cacaaactcc gtttcctgat aacgcagctg
    68761 atgttcagtg ttctgattta atgaagactt gaacataaca tgtatatttg gcgcaatctg
    68821 ctcaatgtga ttataaatct gcgaggtcag aatgctgtct aacgggctgc aaacacaaag
    68881 atgaaataca cgttcactac tcgcgggttc aaaacctgaa ccaggcaatt cattttgtac
    68941 tagttgcaat gcctggcgaa ctgaaccaaa aagttgaaat gcgcgagcag tcggttgaat
    69001 accacggcca taacgaacaa aaagctcgtc attaaacatc accttcaggc gtgcaacagc
    69061 gttactgacc gcaggttgcg acatacccag aacatgagcg gcacgggtaa tgttttgctc
    69121 ctgcatcacg gcatcgaaaa cggttaataa gttgagatcg accatgcgta gctgtggctt
    69181 gcttaactcc gccgtctctg aatgatctgt ttgtacctct ggcatactta actccactgt
    69241 cacacttaac tccctttccc ttattggaat gcagagaaat aatcctgaag aatatgattt
    69301 atcatgcata taaaataaga aaaaggaaaa tgagtaaaat taggaaaaca taaagatacg
    69361 ggttctgata aaaacagaat ccattgccgt ggaatgagtc atttaccaca gcataataat
    69421 ccataatgat tttgttgcga aaacaatcta atcata
//
LOCUS       DAPHKZ010000010        68265 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.010, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000010 DAPHKZ010000000
VERSION     DAPHKZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 68265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68265
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.010"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(73..930)
                     /gene="murI"
                     /locus_tag="RH288_000666"
     CDS             complement(73..930)
                     /gene="murI"
                     /locus_tag="RH288_000666"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418402.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDV4029763.1"
                     /translation="MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLL
                     PDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPA
                     LREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEML
                     GSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPGAEQLLPVLQRYGFE
                     TLEKLAVLG"
     gene            complement(875..2719)
                     /gene="btuB"
                     /locus_tag="RH288_000667"
     CDS             complement(875..2719)
                     /gene="btuB"
                     /locus_tag="RH288_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HDV4029764.1"
                     /translation="MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLA
                     PTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDG
                     VRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEI
                     SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFL
                     SKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRY
                     NGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAG
                     VDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
                     WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSL
                     WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     regulatory      complement(2784..2974)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            3088..4188
                     /gene="trmA"
                     /locus_tag="RH288_000668"
     CDS             3088..4188
                     /gene="trmA"
                     /locus_tag="RH288_000668"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HDV4029765.1"
                     /translation="MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHY
                     RMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTK
                     IELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELY
                     CGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHKVERLALFDQFPYTHHMECGVLLTAK"
     gene            complement(4228..4587)
                     /locus_tag="RH288_000669"
     CDS             complement(4228..4587)
                     /locus_tag="RH288_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HDV4029766.1"
                     /translation="MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLV
                     LTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIM
                     VFWIGAKMRNRKQEVAE"
     gene            complement(4587..5237)
                     /gene="fabR"
                     /locus_tag="RH288_000670"
     CDS             complement(4587..5237)
                     /gene="fabR"
                     /locus_tag="RH288_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HDV4029767.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE"
     gene            5568..6968
                     /gene="sthA"
                     /locus_tag="RH288_000671"
     CDS             5568..6968
                     /gene="sthA"
                     /locus_tag="RH288_000671"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HDV4029768.1"
                     /translation="MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTH
                     PRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            complement(6951..7868)
                     /gene="oxyR"
                     /locus_tag="RH288_000672"
     CDS             complement(6951..7868)
                     /gene="oxyR"
                     /locus_tag="RH288_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HDV4029769.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVG
                     PYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
                     FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGS
                     PLRSRYEQLAEAIRARMDGHFDKVLKQAV"
     gene            complement(8135..9508)
                     /gene="argH"
                     /locus_tag="RH288_000673"
     CDS             complement(8135..9508)
                     /gene="argH"
                     /locus_tag="RH288_000673"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDV4029770.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     ASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDT
                     WLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIA
                     FAQARLG"
     gene            complement(9569..10345)
                     /gene="argB"
                     /locus_tag="RH288_000674"
     CDS             complement(9569..10345)
                     /gene="argB"
                     /locus_tag="RH288_000674"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418394.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDV4029771.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGL
                     FLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKV
                     NAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA"
     gene            complement(10353..11357)
                     /gene="argC"
                     /locus_tag="RH288_000675"
     CDS             complement(10353..11357)
                     /gene="argC"
                     /locus_tag="RH288_000675"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDV4029772.1"
                     /translation="MLNTLIVGASGYAGAELVTYVNRHPHMNITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDISEFSPGVDVVFLATAHEVSHDLAPQFLEAGCVVFDL
                     SGAFRVNDATFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
                     LALKPLIDADLLDLNQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     ATHLGADVIFTPHLGNFPRGILETITCRLKSGVTQAQVAQVLQQAYAHKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQCANIRFGYAETQSLI
                     "
     gene            11511..12662
                     /gene="argE"
                     /locus_tag="RH288_000676"
     CDS             11511..12662
                     /gene="argE"
                     /locus_tag="RH288_000676"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HDV4029773.1"
                     /translation="MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFK
                     DLGFNVEVQPVPGTRNKFNMLASIGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHD
                     GKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTAL
                     RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQ
                     LRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNG
                     LLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEA
                     PFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH"
     gene            13137..15788
                     /gene="ppc"
                     /locus_tag="RH288_000677"
     CDS             13137..15788
                     /gene="ppc"
                     /locus_tag="RH288_000677"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HDV4029774.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKS
                     SRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
                     LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKAT
                     DLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARL
                     KGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAE
                     TREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDVYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKEL
                     RNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKE
                     GQEPDPRVEQALMVTIAGIAAGMRNTG"
     gene            15970..17703
                     /locus_tag="RH288_000678"
     CDS             15970..17703
                     /locus_tag="RH288_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HDV4029775.1"
                     /translation="MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTN
                     GIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLF
                     VMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
                     YGLILHPIAMNTFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNE
                     NNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLT
                     VFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLNDPAPKKLIIVHLLGT
                     HIKYKYRYPENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAA
                     NPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFS
                     QDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            17918..18769
                     /locus_tag="RH288_000679"
     CDS             17918..18769
                     /locus_tag="RH288_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV4029776.1"
                     /translation="MYHDVSYLLSRLINGPLSLRQIYFASSNGPVPDLAYQVDFPRLE
                     IVLEGEFVDTGAGATLVPGDVLYVPAGGWNFPQWQAPATTFSVLFGKQQLGFSVVQWD
                     GKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EKPTTPE"
     gene            complement(18756..19097)
                     /locus_tag="RH288_000680"
     CDS             complement(18756..19097)
                     /locus_tag="RH288_000680"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDV4029777.1"
                     /translation="MAYLVAVTACVSGVAHTYMAAERLEKLCLLEKWGVSIETQGALG
                     TENRLADEDIRRADVALLITDIELAGAERFEHCRYVQCSIYAFLREPQRVMSAVRKVL
                     SAPQQTHLILE"
     gene            complement(19099..19977)
                     /locus_tag="RH288_000681"
     CDS             complement(19099..19977)
                     /locus_tag="RH288_000681"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418387.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[formate-C-acetyltransferase]-activating enzyme"
                     /protein_id="HDV4029778.1"
                     /translation="MTSSAGQRISCNVVETRRDDVARIFNIQRYSLNDGEGIRTVVFF
                     KGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCLRDADECPSGAFERIGRDISLDA
                     LEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLRLWGVSCAIETAGDAPAS
                     KLLPLAKLCDEVLFDLKIMDATQARDVVKMNLPRVLENLRLLVSEGVNVIPRLPLIPG
                     FTLSRENMQQALDVLIPLNIRQIHLLPFHQYGEPKYRLLGKTWSMKEVPAPSSADVAT
                     MREMAERAGLQVTVGG"
     gene            complement(19943..22240)
                     /locus_tag="RH288_000682"
     CDS             complement(19943..22240)
                     /locus_tag="RH288_000682"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDV4029779.1"
                     /translation="MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRA
                     KATEYILEHVEISIRDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFA
                     ISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIID
                     YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCT
                     DAQRREELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYM
                     LPFYQTSLTQGEDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT
                     ENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIF
                     NDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN
                     EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR
                     DITDGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE
                     KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVP
                     LGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVK
                     FTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA
                     GYSAFFVELSKEIQDDIIRRTAHQL"
     gene            complement(22291..22611)
                     /locus_tag="RH288_000683"
     CDS             complement(22291..22611)
                     /locus_tag="RH288_000683"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDV4029780.1"
                     /translation="MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIG
                     LENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHL
                     AQTA"
     gene            complement(22626..23705)
                     /locus_tag="RH288_000684"
     CDS             complement(22626..23705)
                     /locus_tag="RH288_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDV4029781.1"
                     /translation="MNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGA
                     VPDAVADPNLKKLFDIGVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAG
                     FFGALIAGIIGGIVVHYLKKIPVHKVLRSVMPIFIIPIVGTLITAGIMMWGLGEPVGA
                     LTNSLTQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAI
                     AAVGICIPPLGMGLATLIGRKNFSAEERETGKAALVMGCVGVTEGAIPFAAADPLRVI
                     PSIMVGSVCGAVTAALVGAQCYAGWGGLIVLPVVEGKLGYIAAVAVGAVVTAVCVNVL
                     KSLARKNGSSTDEKEDDLDLDFEIN"
     gene            24014..26515
                     /gene="ptsP"
                     /locus_tag="RH288_000685"
     CDS             24014..26515
                     /gene="ptsP"
                     /locus_tag="RH288_000685"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDV4029782.1"
                     /translation="MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRK
                     GNAKSALALIGTDTLAGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDE
                     LEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKGVDAEQSALE
                     NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVAS
                     ANHFCEEFSRSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELT
                     PSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQQQTIYIDG
                     NAGAIVVEPGEAVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVE
                     AQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGG
                     DKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSM
                     EEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIDQCCEEIDFFSIGSN
                     DLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVL
                     PLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRKLLNQAMACRTSLEVEHLLAQFRM
                     TQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFST
                     GLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIF
                     SRLARRIMHEEFRNALVNAASADAIASLLQHELEL"
     gene            26527..27189
                     /gene="fsa"
                     /locus_tag="RH288_000686"
     CDS             26527..27189
                     /gene="fsa"
                     /locus_tag="RH288_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDV4029783.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLP
                     RLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKILKKE
                     GITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQTLLEMHAPES
                     MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTT
                     HL"
     gene            27200..28303
                     /gene="gldA"
                     /locus_tag="RH288_000687"
     CDS             27200..28303
                     /gene="gldA"
                     /locus_tag="RH288_000687"
                     /EC_number="1.1.1.6"
                     /EC_number="1.1.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418380.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional L-1,2-propanediol
                     dehydrogenase/glycerol dehydrogenase"
                     /protein_id="HDV4029784.1"
                     /translation="MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFA
                     QSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKA
                     LAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGE
                     TIHNMPGGATPDQVYAALLVADQYGQRFLQEWE"
     gene            28578..29195
                     /locus_tag="RH288_000688"
     CDS             28578..29195
                     /locus_tag="RH288_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1287 domain-containing protein"
                     /protein_id="HDV4029785.1"
                     /translation="MKASLALLSLLTAFTSHSLKSPAVPPTVVQIQANTNLAIADGAR
                     QQIGSTLFYDPAYVQLTYPGGDVPQERGVCSDVVIRALRSQKVDLQKLVHEDMAKNFA
                     EYPQKWKLKRPDSNIDHRRVPNLETWFSRHDKTRPTSKNPSDYQAGDIVSWRLDNGLA
                     HIGVVSDGFARDGTPLVIHNIGAGAQEEDVLFNWRMVGHYRYFVK"
     gene            complement(29222..30127)
                     /gene="yijE"
                     /locus_tag="RH288_000689"
     CDS             complement(29222..30127)
                     /gene="yijE"
                     /locus_tag="RH288_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine transporter YijE"
                     /protein_id="HDV4029786.1"
                     /translation="MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTAL
                     RCIFGALVLFIVLLLRGRGMRPTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAIL
                     SYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
                     GVSWGASAIVAKRLYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFW
                     ALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGS
                     GIVLIVLALALVSRKKKEAVSVKRI"
     gene            complement(30220..32400)
                     /gene="katG"
                     /locus_tag="RH288_000690"
     CDS             complement(30220..32400)
                     /gene="katG"
                     /locus_tag="RH288_000690"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HDV4029787.1"
                     /translation="MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAG
                     PTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDI
                     IDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVR
                     ALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDI
                     EMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFD
                     GSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKFTASRADL
                     VFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            complement(32729..33619)
                     /gene="metF"
                     /locus_tag="RH288_000691"
     CDS             complement(32729..33619)
                     /gene="metF"
                     /locus_tag="RH288_000691"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDV4029788.1"
                     /translation="MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTI
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            complement(33968..36400)
                     /gene="metL"
                     /locus_tag="RH288_000692"
     CDS             complement(33968..36400)
                     /gene="metL"
                     /locus_tag="RH288_000692"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HDV4029789.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADSLISAF
                     VSDLERLAALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAE
                     RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLIEFQVPASQDFKLAH
                     KEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD
                     GLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLDFASHGF
                     HVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAR
                     EAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNEQMVQRLEAAREMGLVLRYVA
                     RFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(36403..37563)
                     /gene="metB"
                     /locus_tag="RH288_000693"
     CDS             complement(36403..37563)
                     /gene="metB"
                     /locus_tag="RH288_000693"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HDV4029790.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
                     HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDV
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            37840..38157
                     /gene="metJ"
                     /locus_tag="RH288_000694"
     CDS             37840..38157
                     /gene="metJ"
                     /locus_tag="RH288_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HDV4029791.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPET
                     WEY"
     gene            38341..38949
                     /locus_tag="RH288_000695"
     CDS             38341..38949
                     /locus_tag="RH288_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX family permuted papain-like enzyme"
                     /protein_id="HDV4029792.1"
                     /translation="MKNRLLILSLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATH
                     TDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEKGKYVVRRVEGGLSVEQQQK
                     LAQTAKRYLGKPYDFSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSSPQV
                     QAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW"
     gene            complement(39010..39222)
                     /gene="rpmE"
                     /locus_tag="RH288_000696"
     CDS             complement(39010..39222)
                     /gene="rpmE"
                     /locus_tag="RH288_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDV4029793.1"
                     /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF
                     TGKQRDVATGGRVDRFNKRFNIPGSK"
     gene            39425..41623
                     /gene="priA"
                     /locus_tag="RH288_000697"
     CDS             39425..41623
                     /gene="priA"
                     /locus_tag="RH288_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDV4029794.1"
                     /translation="MPVAHVALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIG
                     IVVSVSDASELPLNELKAVVEVLDSEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI
                     LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
                     NDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAVGAIHSAADTFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL
                     DLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQHHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPGVPIS
                     RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE
                     RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILSSPLADEKLWVLGPVPALAPK
                     RGGRWRWQILLQHPSRVRLQHIINGTLALINTIPDSRKVKWVLDVDPIEG"
     gene            41779..42804
                     /gene="cytR"
                     /locus_tag="RH288_000698"
     CDS             41779..42804
                     /gene="cytR"
                     /locus_tag="RH288_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HDV4029795.1"
                     /translation="MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV
                     EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI
                     GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
                     LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD
                     PQYIARGDFTFEAGSKAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS
                     IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIR
                     GSTRALP"
     gene            42896..43855
                     /gene="ftsN"
                     /locus_tag="RH288_000699"
     CDS             42896..43855
                     /gene="ftsN"
                     /locus_tag="RH288_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HDV4029796.1"
                     /translation="MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVL
                     VTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEP
                     SAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
                     QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTT
                     AQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSK
                     ITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG"
     gene            43948..44478
                     /gene="hslV"
                     /locus_tag="RH288_000700"
     CDS             43948..44478
                     /gene="hslV"
                     /locus_tag="RH288_000700"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HDV4029797.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
                     IYTNHFHTIEELSYKA"
     gene            44488..45819
                     /gene="hslU"
                     /locus_tag="RH288_000701"
     CDS             44488..45819
                     /gene="hslU"
                     /locus_tag="RH288_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HDV4029798.1"
                     /translation="MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
                     KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKI
                     KDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGA
                     RRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL"
     gene            45886..46812
                     /gene="menA"
                     /locus_tag="RH288_000702"
     CDS             45886..46812
                     /gene="menA"
                     /locus_tag="RH288_000702"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDV4029799.1"
                     /translation="MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPL
                     VALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIIT
                     VVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLV
                     FFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVV
                     RLGEVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDP
                     VAMRPMLERTVKGALLTNLLFVLGIFLSQWAA"
     gene            46905..47390
                     /gene="rraA"
                     /locus_tag="RH288_000703"
     CDS             46905..47390
                     /gene="rraA"
                     /locus_tag="RH288_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HDV4029800.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(47475..47720)
                     /gene="zapB"
                     /locus_tag="RH288_000704"
     CDS             complement(47475..47720)
                     /gene="zapB"
                     /locus_tag="RH288_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HDV4029801.1"
                     /translation="MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQ
                     NAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV"
     gene            48145..48990
                     /gene="glpF"
                     /locus_tag="RH288_000705"
     CDS             48145..48990
                     /gene="glpF"
                     /locus_tag="RH288_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein GlpF"
                     /protein_id="HDV4029802.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAA
                     LVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAG
                     WGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSE
                     QKASL"
     gene            49013..50521
                     /gene="glpK"
                     /locus_tag="RH288_000706"
     CDS             49013..50521
                     /gene="glpK"
                     /locus_tag="RH288_000706"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDV4029803.1"
                     /translation="MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPG
                     WVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAI
                     VWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
                     LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEV
                     RRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNT
                     GEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFA
                     TKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDV
                     LEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGL
                     AVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE"
     gene            50656..51666
                     /gene="glpX"
                     /locus_tag="RH288_000707"
     CDS             50656..51666
                     /gene="glpX"
                     /locus_tag="RH288_000707"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HDV4029804.1"
                     /translation="MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
                     ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSD
                     NVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVH
                     IL"
     gene            51763..52509
                     /gene="fpr"
                     /locus_tag="RH288_000708"
     CDS             51763..52509
                     /gene="fpr"
                     /locus_tag="RH288_000708"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HDV4029805.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEID
                     GERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDE
                     VPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK
                     RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(52514..52942)
                     /gene="uspD"
                     /locus_tag="RH288_000709"
     CDS             complement(52514..52942)
                     /gene="uspD"
                     /locus_tag="RH288_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspD"
                     /protein_id="HDV4029806.1"
                     /translation="MAYKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDDGLS
                     ELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWPKTKLRIERGEMPETLLEIMQKE
                     QCDLLVCGHHHSFINRLMPAYRGMINKMSADLLIVPFIDK"
     gene            complement(52969..53268)
                     /locus_tag="RH288_000710"
     CDS             complement(52969..53268)
                     /locus_tag="RH288_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 domain-containing protein"
                     /protein_id="HDV4029807.1"
                     /translation="MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFM
                     TKLKELAAATSSADEGASVAYKIKDLEGQVELDAAFTFSCQAEMIIFELSLRSLA"
     gene            53465..54162
                     /locus_tag="RH288_000711"
                     /pseudo
     CDS             53465..54162
                     /locus_tag="RH288_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(54294..55076)
                     /locus_tag="RH288_000712"
     CDS             complement(54294..55076)
                     /locus_tag="RH288_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV4029808.1"
                     /translation="MSQQRPDRIKQMLHYLWQHRHLSTQQAMELFGYAEATVRRDFQY
                     IVNQYPGMIRGHGCLDFDDSTDDKEYVFDVKRTLQSVAKREIAALARTMIKDGDCFFL
                     DSGSTCLELAKCLADARVKVICNDIKIANELGCFPHVESYIIGGLIRPGYFSVGESLA
                     LEMINAFSVERAFISCDALSLETGITNATMFEVGVKTRIIQRSREVILMADHSKFDAV
                     EPHAVATLSCIKTIISDSGLPETIAQRYQRAGCQLFLPHSIK"
     gene            complement(55093..55725)
                     /locus_tag="RH288_000713"
     CDS             complement(55093..55725)
                     /locus_tag="RH288_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3 epimerase family protein"
                     /protein_id="HDV4029809.1"
                     /translation="MILHPSLASANPLHYGRELTALDNLDFGSLHLDIEDSSFINNIT
                     FGMKTVQAVARQTPHPLSFHFMLARPQRWFNALAEIRPAWIFVHAETLDYPSETLTEI
                     RHTGARAGLVFNPATPIDAWRYLASELDGVMVMTSEPDGQGQRFIPSMCEKIQKVRTA
                     FPQTECWADGGITLAAAQQLAAAGAQHMVIGRALFSSSDYRATLAQFATL"
     gene            complement(55737..56168)
                     /locus_tag="RH288_000714"
     CDS             complement(55737..56168)
                     /locus_tag="RH288_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDV4029810.1"
                     /translation="MINDIKWVQAQRKATDWRQAVEIATRPLVAYGAAQPCYVNGIIE
                     NTLNWGPYYLIAPGIALPHARPEQGANYNQVSITTLRTPVAFGNEECDPVWLLLCVSA
                     TDANAHILTIQRISQFIDSPQRLTAVGNASTDDALFALVSG"
     gene            complement(56299..57105)
                     /gene="sgcQ"
                     /locus_tag="RH288_000715"
     CDS             complement(56299..57105)
                     /gene="sgcQ"
                     /locus_tag="RH288_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA family protein SgcQ"
                     /protein_id="HDV4029811.1"
                     /translation="MSWLKEVIGTEKAVIAMCHLRALPGDPSFDAQLGMNWVIDKAWD
                     DLMALQNGGVDAVMFSNEFSLPYLTKVRPETTAAMARIIGQLMSDIRIPFGVNVLWDP
                     VASFDLAMATGAKFIREIFTGAYASDFGVWDTNVGETIRHQHRIGAGEVKTLFNIVPE
                     AAVYLGNRDICSIAKSTVFNNHPDALCVSGLTAGTRTDSALLKRVKETVPDTVVLANT
                     GVCLENVEEQLSIADGCVTATTFKKDGVFANFVDQARVSQFMEKVHHIRR"
     gene            complement(57118..58431)
                     /locus_tag="RH288_000716"
     CDS             complement(57118..58431)
                     /locus_tag="RH288_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDV4029812.1"
                     /translation="MFDYILSLGGTVFVPIIMIVIGLIFRIPWLQAIKAGVTVGIGFV
                     GMGLVIVMAIDSLSPPIKVMIERFGLALHVFDVGAGPASGVGYATAIGAMIIPVIFLL
                     NVAMLVTRLTKTMNVDIYNYWHYAITGTVVQLMTGSLIYGVLGAICHAALSLKMADWT
                     AKRVQNIVGLEGISIPQGYGSSSVPLFVLLDAIYEKIPFMKGRNIDAQEIQKRYGMVG
                     DPVIIGVVLGLIFGLAAGEGFKGCASLMITVAAIMVLFPRMIRLIVEGLLPISDGARK
                     FFQKYFKGREVYIGLDTAVTLGHPTTIAVGLLLIPIMLILASILPGNKVLPLADLPVA
                     PFFICMATVIHRGDLVRTLISGVIVMITVLLIATQFAPYFTEMALKGGFSFAGESAQI
                     SALSVGNMFGWSISELMSLGIIGVVVAVGIVASVVLFLRKRELSE"
     gene            complement(58443..58721)
                     /locus_tag="RH288_000717"
     CDS             complement(58443..58721)
                     /locus_tag="RH288_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDV4029813.1"
                     /translation="MKKILVACGTGMSTSTMIAHKLQEFLTEQGISATTAQCCLNEIP
                     LNCNGMDLIVTSMRTNSDYGIPTLNGAALLTGINDDALKQQIKALLTQ"
     gene            complement(58718..59839)
                     /locus_tag="RH288_000718"
     CDS             complement(58718..59839)
                     /locus_tag="RH288_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418725.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDV4029814.1"
                     /translation="MSFSVQETLFSLLQHNAISGHENAVADVMLCEFRRQAKEVWRDR
                     LGNVVARYGSDKPDALRLMIFAHMDEVGFMVRKIEPSGFLRFERVGGPAQVTMAGSIV
                     TLTGDKGPVMGCIGIKSYHFAKGDERTQSPSVDKLWIDIGAKDKDDAIRMGIQVGTPV
                     TLYNPPQLLANDLVCSKALDDRLGCTALLGVADAISTMELDIAVYLVASVQEEFNIRG
                     IVPVLRRVKPDLAIGIDITPSCDTPDLHDYSEVRINQGVGITCLNYHGRGTLAGLITP
                     PRLIRMLEQTALEHNIPVQREVAPGVITETGYIQVEQDGIPCASLSIPCRYTHSPAEV
                     ASLRDLTDCIRLLTALAGMSAAHFPVEPDSGTTQEAHPL"
     gene            complement(60084..60200)
                     /locus_tag="RH288_000719"
                     /pseudo
     CDS             complement(60084..60200)
                     /locus_tag="RH288_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227376.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(60238..60456)
                     /locus_tag="RH288_000720"
                     /pseudo
     CDS             complement(60238..60456)
                     /locus_tag="RH288_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348444.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(60625..61371)
                     /locus_tag="RH288_000721"
     CDS             complement(60625..61371)
                     /locus_tag="RH288_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDV4029815.1"
                     /translation="MDIPRIFTISESEHRIHNPFTEEKYATLGRVLRMKPGTRILDLG
                     SGSGEMLCTWARDHGITGTGIDMSSLFTAQAKRRAEELGVSERVHFIHNDAAGYVANE
                     KCDVAACVGATWIAGGFAGAEELLAQSLKPGGIMLIGEPYWRQLPATEEIAQACGVSS
                     TSDFLTLPGLVGAFDDLGYDVVEMVLADQEGWDRYEAAKWLTMRRWLEANPDDDFAAE
                     VRAELNIAPKRYVTYARECFGWGVFALIAR"
     gene            complement(61427..61972)
                     /locus_tag="RH288_000722"
     CDS             complement(61427..61972)
                     /locus_tag="RH288_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV4029816.1"
                     /translation="MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDES
                     ARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMHILAPLAVIPEYQGMGVGGRLIR
                     TGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
                     QPMTLTGHIRCADPDETGALT"
     gene            complement(61984..62241)
                     /locus_tag="RH288_000723"
     CDS             complement(61984..62241)
                     /locus_tag="RH288_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029817.1"
                     /translation="MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLT
                     DCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRAQLDNR"
     gene            complement(62618..62863)
                     /locus_tag="RH288_000724"
                     /pseudo
     CDS             complement(62618..62863)
                     /locus_tag="RH288_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001420158.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            62979..64219
                     /locus_tag="RH288_000725"
                     /pseudo
     CDS             62979..64219
                     /locus_tag="RH288_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378101.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase"
     gene            complement(64802..65782)
                     /locus_tag="RH288_000726"
     CDS             complement(64802..65782)
                     /locus_tag="RH288_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="9-O-acetyl-N-acetylneuraminic acid deacetylase"
                     /protein_id="HDV4029818.1"
                     /translation="MNAIISPDYYYVLTVAGQSNAMAYGEGLPLPDREDAPHPRIKQL
                     ARFAHTHPGGPPCHFNDIIPLTHCPHDVQDMQGYHHPLATNHQTQYGTVGQALHIARK
                     LLPFIPDNAGILIVPCCRGGSAFTAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
                     RAALAKNPQNKFLGACWMQGEFDLMTSDYASHPQHFNHMVEAFRRDLKQYHSQLNNIT
                     DAPWFCGDTTWYWKENFPHSYEAIYGNYQNNVLANIIFVDFQQQGERGLTNAPDEDPD
                     DLSTGYYGSAYRSPENWTTALRSSHFSTAARRGIISDRFVEAILQFWRER"
     gene            complement(65847..66953)
                     /gene="nanM"
                     /locus_tag="RH288_000727"
     CDS             complement(65847..66953)
                     /gene="nanM"
                     /locus_tag="RH288_000727"
                     /EC_number="5.1.3.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418730.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HDV4029819.1"
                     /translation="MNKTITALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
                     LGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGNLYVFGGIGKNSEGLTQ
                     VFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
                     AGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNK
                     GDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLAPVSSPDGVAGGFAGISNDSLIF
                     AGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPW
                     NNSLLIIGGETAGGKAVTDSVLITVKDNKVTVQN"
     gene            complement(66973..67689)
                     /gene="nanC"
                     /locus_tag="RH288_000728"
     CDS             complement(66973..67689)
                     /gene="nanC"
                     /locus_tag="RH288_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313297.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid outer membrane channel
                     NanC"
                     /protein_id="HDV4029820.1"
                     /translation="MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLK
                     VSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHF
                     SSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYH
                     INSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGV
                     YNGRDNLSENSYRIGVSFKL"
BASE COUNT        16770 a        18125 c        17320 g        16050 t
ORIGIN      
        1 ttatagggag ttattccggc ctgacaagag gaaatttaaa ataattttct gaccgcgcaa
       61 cattcaacca aatcagccta aaactgccag tttttcgagc gtttcgaagc cgtaacgctg
      121 taaaacgggc aataattgtt cagctcctgg cgtcattgcc atacaaaagg caatattcgc
      181 atcggcagat tttgcatccg gggcttcatg ttctaacaac caggccgttc ggcgagcaat
      241 cgctgcgcca gaatccacca gccgggttcc ctctggcagc acttgtaaca gttcttcttg
      301 tagtagaggg aaatgggtgc aacccaatac aacggtatct ggcggctctt tcattcttaa
      361 ccacgggcgt aggatacgtt ttagtgcatc cagagaaaca tcttcgccat gtagcttcgc
      421 ttcagccaac tcaaccatct ctgccgagcc cagcatttct atctggcatt cattagcgaa
      481 acgcgcgatc agctcatgag tataagaacg tttaactgtt ccgcgggttg ccagtaatcc
      541 gacaatgcca tttgccgtca gacgtgcagc aggtttaatc gccggcacga caccaacaac
      601 cgggaagtcg aacttttcgc gtaatgcagg aagtgaaacg gtactggcag tgttgcaagc
      661 gaccacagcc agcgcaaggg gataacgttc ttgcaccgcg gtgacaattg ccaccactcg
      721 ctcaacaata aacgcttcgc ttttttcgcc atacgggaaa gcgacgttat cgaaagcata
      781 aatgtaatgg agatccggta agagatgccg gatctcgtca tagaccgaca acccaccgac
      841 gccggagtca aacaccagca cggtgggacg tggttcagaa ggtgtagctg ccagacaagg
      901 tgtattcccg tcctgcagtt tggtagccat agactgtctc ataatctttg tcgaacaggt
      961 tggctatttt accacgaact gtcaggtgag aggtgaccgg atacgcaacc gcaagatccc
     1021 acaagctcac accgcccatt ttaacggttt gataaggata agatgagtaa tccttatcat
     1081 agcgagtgcc taaatactga taagtaatac cccagtcgaa gtcatacaac tgccagtcga
     1141 gctggtattt cacctgctgt ttagcacggc gtaacaacgg cgtgtcggta atcgcattgc
     1201 gcgcatcgac ataatcataa ctcacagtat gcgtcagtgg tccggtatca aaattggcgg
     1261 tcgcctcgac gcccttaatc cgcgctttcc cttcgttgta atatttcagg gtgtgatcat
     1321 cataatcgat caagtcactg acatcgttac gatatccgga aatacgccag ttcaccccag
     1381 cggttaagcc ttcaaacgcg ccttcccact gtttgctttt ctccgggtcc agattcggat
     1441 ttccgtagaa gccatacagt tgccccagat ttggtgcctt ataagatgtc ccgtaggaag
     1501 caatgaagcg ataaccttcg atgaattccc aaccggcgct ggtttgccag gttccatgac
     1561 gaccaaactg tgagttatcg tcactgcgtg ctgcgccttc aaaggtaaaa tcgccgactt
     1621 gttgcagccc ggtcagatag atgccggtat tacgttgatc atatccatcc tcaacataac
     1681 ctgtacccgg cgtcgtagtc tgtttctgcc agtcgacacc cgcaccaata ctaccgtgac
     1741 caacgatgac attgtttgcc cactggacgg tgtattgctt catctcatcg agcgtcgccg
     1801 acgaatcata acgaccataa tggggatcgt agttgtaatc tttgctatgg ctatagctgg
     1861 taatgagttg tgatttaatc agttcgccgt tatagcgcag cccggcgtcc caactttggc
     1921 tatagagttt acgggtatcg agcaacggtg aaccgggaga ataatacgcg tcataattgg
     1981 tacggttatc atagccatag ccgcgcacaa agccgctcca ggcatcagta aagttatgct
     2041 ccagcgcgcc ataaagcgtt ttacttaaaa aaccatcgtt atctgtctgc gcttgcgttc
     2101 cggtattacc ataggcaaca acatcataac catgagtatg ggcataatcg cccaacagcg
     2161 ttacccgtgt cttatccccc agttgttgct gcgtagagac atcatagttc tgataactat
     2221 tgcttcccca ccctgctgaa atttccgttc cgggttcatc gcgcgtcgtg atgatattca
     2281 ccaccccgcc tattgcatcg gaaccataaa cagcggagcg cggcccacgg atatattcaa
     2341 cacgctggac aagcgcaata gggaactggc taaggtcggc agaaccactc acccccgcca
     2401 gattcaggcg tacgccatca attaacacca acacatgact ggcatttgta ccgcgaataa
     2461 aaatagatga gagctgacct gaaccgccgt tttgggtgat atcgacgccc ggaagacggc
     2521 gcagcacatc attgaccgag gtcgactgcc agcggtcgat atcctgacgg gtcacaacgg
     2581 tggttggtgc aagcacagtg ctgcgcggct gttcaaaacg gttagcagta acgacgagag
     2641 tatccgggct ggtatcctgt gcccaagcgg aaaatgccgt gacggaacac gccgtcagca
     2701 gcgaagcttt tttaatcatt gtaaagcatc cacaatagaa gaaggatgcc gcaggtttca
     2761 tcaatattac gcgatgatga gaaccagatg cgacgttggc cggcaggtct tcgggcttgg
     2821 aggggtatct aagatactaa gagatgatga cttcccaccg aatggcagtg tccgcataac
     2881 gcaatcatcg cacctttcct taccgctgcg cgtcagctcc agattcgcac tggattccct
     2941 attaactcac aggaccggca agtggatgct acaggttgta acaagttact gtccagacgt
     3001 agctcacaaa taggaattca tcaagatctg gacatctgat gagcaatccc tacaatcgcc
     3061 gcgtacttta atttttcagg atacatcatg acccccgaac accttccaac agaacagtat
     3121 gaagcgcagt tagccgaaaa agtggtacgt ttgcaaagta tgatggcacc gttttctgac
     3181 ctggttccgg aagtgtttcg ctcgccggtc agtcattacc ggatgcgcgc ggagttccgc
     3241 atctggcacg atggcgatga cctgtatcac atcattttcg atcaacaaac caaaagccgc
     3301 atccgcgtgg atagcttccc cgccgccagt gaacttatca accagttgat gacggcgatg
     3361 attgcgggtg tgcgtaataa tcccgttctg cgccacaagt tgttccagat tgattacctc
     3421 actacgctga gtaatcaggc ggtggtttcc ctgctatacc ataagaagct ggatgatgag
     3481 tggcgtcagg aagcggaggc cctgcgcgat gcactgcgcg cgcagaatct gaatgtgcat
     3541 ctgattggtc gggcaacgaa aaccaaaatc gagctggatc aggattacat cgatgaacgt
     3601 ctgccggtcg cagggaaaga gatgatctac cgtcaggtag aaaacagctt tacccagccg
     3661 aacgcggcga tgaatattca gatgctggaa tgggcgctgg acgtaaccaa aggctcaaaa
     3721 ggcgatttac tggagctgta ctgcggcaac ggtaactttt cattagcgct ggcgcgtaat
     3781 tttgatcggg tattagccac cgaaatcgct aagccgtcgg ttgctgctgc gcaatacaac
     3841 atcgcagcta accatattga taacgtacaa attattcgta tggcggcaga agaatttact
     3901 caggcgatga atggtgtgcg cgagtttaac cgcctgcaag ggatcgactt aaagagttat
     3961 cagtgcgaaa ccatttttgt cgacccaccg cgcagcggtc tggacagtga aaccgagaaa
     4021 atggtgcagg cgtatccgcg tattttgtac atctcctgta acccggaaac gttatgcaag
     4081 aatctggaaa cattaagcca gacgcacaag gtcgaacgtc tggctctgtt tgatcagttc
     4141 ccctacacgc accatatgga gtgcggcgta ttactgaccg cgaagtaaaa cccatgccgg
     4201 atgcgccagc atccggcata ataccgatta ctcagcaact tcctgcttac ggttacgcat
     4261 cttcgcgcca atccagaaca ccataatgac ggagagtact gccgggaaga agttagagcc
     4321 gatatccgga tattccgcac gaactaccgt gctgtacagc agtacgccga gaataaaaca
     4381 ggcagctgcc agacccggca agcctaccgg catagtgcga ttaagataac gttgatgcag
     4441 gcagtaaacc gtcagcacca gggaaataat cgggaataca gaaaatggca caatggagct
     4501 aaacagcgct gcgaaagtac cattaatcga taagccagca actaacgcca gcagcagcgt
     4561 acctctatct tgatttgctt gtttcattac tcgtccttca catttcccgg aataattgcg
     4621 gttttctctt gttcacggcg ataccagtaa taagcccctt tcgaaatcat tcgcagttgc
     4681 agtaccagtc gctcttctaa ttgccgacgt tgttcgacgc cgacgtccaa cgcctcggca
     4741 cccgcactga agacaattgt caccattgct tcggcttgcg cttcagtaaa cgcacgcggc
     4801 atatggtttt cgagttccag atagtccgca agttccgcaa tgaagtgctg aatttcacgc
     4861 gcaacggcgg cacgaaacgc agcggaggtg ccggagcgtt cccgcaataa taaccggaag
     4921 gcgttaggat tattaccgat gaactccata aatgtggaga ccgaggtgcg gatcacactc
     4981 ccgcctttgg cgatacgctg acgcgcctgg cgcatgagtt ggcgtagcat taaaccgctc
     5041 tcatcaacca tggtcagacc cagttcgtct acgtcgcgga aatgccgata aaaagaggtg
     5101 ggagcaatgc ccgcttcacg cgccacttca cgcaaactca ggctggcgaa gctgcgttca
     5161 gcacttaatt ggctaaatgc ggcttccacc agcgaacggc gggttttttc tttttgttgc
     5221 gctcttacgc ccatcacgat gtctgaatcc ttgccaaaag tactgctggc actataccag
     5281 agaatgaaca tactggattg ctccagtatt gtgaatgaac ggtaacgcaa taaaacatat
     5341 ttactgcaat tctttggccg gttcttttac gtacagcgga aacctgccgc ttaaacggag
     5401 agtatcgtcg ataaaaatcc aataaaacgt cagggcaaaa gtaagaaaca gacaaagcaa
     5461 aggccgctca ggatatagcc agataaatga cggggatcaa ttggcttacc cgcgataaaa
     5521 tgttaccatt ctgttgcttt tatgtataag aacaggtaag ccctaccatg ccacattcct
     5581 acgattacga tgccatagta ataggttccg gccccggcgg cgaaggcgct gcaatgggcc
     5641 tggttaagca aggtgcgcgc gtcgcagtta tcgagcgtta tcaaaatgtt ggcggcggtt
     5701 gcacccactg gggcaccatc ccgtcgaaag ctctccgtca cgccgtcagc cgcattatag
     5761 aattcaatca aaacccactt tacagcgacc attcccgact gctccgctct tcttttgccg
     5821 atatccttaa ccatgccgat aacgtgatta atcaacaaac gcgcatgcgt cagggatttt
     5881 acgaacgtaa tcactgtgaa atattgcagg gaaacgctcg ctttgttgac gagcatacgt
     5941 tggcgctgga ttgcccggac ggcagcgttg aaacactaac cgctgaaaaa tttgttattg
     6001 cctgcggctc tcgtccatat catccaacag atgttgattt cacccatcca cgcatttacg
     6061 acagcgactc aattctcagc atgcaccacg aaccgcgcca tgtacttatc tatggtgctg
     6121 gagtgatcgg ctgtgaatat gcgtcgatct tccgcggtat ggatgtaaaa gtggatctga
     6181 tcaacacccg cgatcgcctg ctggcatttc tcgatcaaga gatgtcagat tctctctcct
     6241 atcacttctg gaacagtggc gtagtgattc gtcacaacga agagtacgag aagatcgaag
     6301 gctgtgacga tggtgtgatc atgcatctga agtcgggtaa aaaactgaaa gctgactgcc
     6361 tgctctatgc caacggtcgc accggtaata ccgattcgct ggcgttacag aacattgggc
     6421 tagaaactga cagccgcgga cagctgaagg tcaacagcat gtatcagacc gcacagccac
     6481 acgtttacgc ggtgggcgac gtgattggtt atccgagcct ggcgtcggcg gcctatgacc
     6541 aggggcgcat tgccgcgcag gcgctggtaa aaggcgaagc caccgcacat ctgattgaag
     6601 atatccctac cggtatttac accatcccgg aaatcagctc tgtgggcaaa accgaacagc
     6661 agctgaccgc aatgaaagtg ccatatgaag tgggccgcgc ccagtttaaa catctggcac
     6721 gcgcacaaat cgtcggcatg aacgtgggca cgctgaaaat tttgttccat cgggaaacaa
     6781 aagagattct gggtattcac tgctttggcg agcgcgctgc cgaaattatt catatcggtc
     6841 aggcgattat ggaacagaaa ggtggcggca acactattga gtacttcgtc aacaccacct
     6901 ttaactaccc gacgatggcg gaagcctatc gggtagctgc gttaaacggt ttaaaccgcc
     6961 tgttttaaaa ctttatcgaa atggccatcc attcttgcgc ggatggcctc tgccagctgc
     7021 tcatagcggc tgcgcagcgg tgagccagga cgataaacca ggccaatagt gcggcgtggt
     7081 tccggcttaa tgcacggcag ataaacaacc ccatcgcgtt tgcgctccgg cggcacagcc
     7141 agcgctggca gtaaagtgat cccgctacct gccgccacca tgttgcgcag agtttccagg
     7201 ctggtcgcgc ggaagtgtgt atcttcatcc gccccggctt caaaacagaa acccattgcc
     7261 tgatcgcgca aacagtgacc atcttccagc atcagcagtt tttcccctgc cagatcggcc
     7321 atcggtacgc attcgcggtt cgcccacggg tgatcttcat agatagccag caacattggc
     7381 tcatcaaaca acggcacttc aatgaatgct tcgctctctt tcaccagcgc gaggatcacg
     7441 caatcgagtt tgccgctgtc cagttgcgcc agtaactggt gggtctgtgc ttcatgcaga
     7501 tacatttcca gctttggaaa ggtctggtgc agcataggga taatatgcgg tagcaggtac
     7561 ggtccaactg tgggaatcaa accaatgtgc agcggtccgg acatcgtctc gccctgctgg
     7621 cttgccatct ctttaaggac tttcacctca cgcagcacgg tacgcgcctg atccaccagc
     7681 agcattcccg cctgggtgaa caacacttta cggctggtcc gctccagcaa catcacgccc
     7741 agctcatctt ccagcttacg aatttgcccg ctaagcgtcg gctggctaac gtggcaggaa
     7801 tctgccgcac gccgaaaatg gcggtgttca gccaatgcca ccaggtactc aagatcacga
     7861 atattcatta tccatcctcc atcgccacga tagttcatgg cgataggtag aatagcaatg
     7921 aacgattatc cctatcaagc attctgactg ataattgctc acagaaacgg agcggcacct
     7981 cttttaaccc ttgaagtcac tgcccgtttc gagagtttct caactcgaat aactaaagcc
     8041 aacgtgaact tttgcggatc tccaggatcc gctttttttt gccataaaaa agcccggcga
     8101 taagccaggc tcaaatttat acatataaat gttcttaccc taaccgagcc tgcgcaaaag
     8161 caatcgcctg cgccacctgc tgcggtgaga cgccgccttt tgccgcacgc ttgtcgaggc
     8221 acgattgcag cgacagaatc ggatagacat cttcgtcaat cacctgactg aatttctgca
     8281 actcactgag cggcagatct tccagcggtt tgccctgacg aatggcttcc accaccgctt
     8341 caccaacaat atggtgcgcc tcgcggaacg gtacgccttt cgccaccaga taatccgcca
     8401 gttcggtggc gttggcgtaa ccctgctgag ccgcttcctg gcaacgtgga cgtttcacct
     8461 gaatgccgtc cagcaccagc gccgccatat gcaggcagtc cagccaggta tcgagcgcgt
     8521 cgaacagacc ttctttgtct tcctgcatat ctttgttgta agccagcggc aaacctttca
     8581 gcgtcatcat catgccggtt aacgccccct gcacccggcc gcatttaccg cgaatcagct
     8641 ccagcgcatc cgggtttttc ttctgcggca ttaatgatga accggaagtc acgcggtcag
     8701 aaagctccac aaaccccgct tcgccggtgt taaagaaaat cagatcttca gcaaaacgcg
     8761 acagatgcac catgccgata gcggcagcag aaagcagttc caacacatgg tcacggtcag
     8821 aaacgctgtc gagactgtta cgggtcgccg aagcaaagcc cagccagcct gctaactgtt
     8881 cacggtcgat ttcataggcc gttcccgcca gcgcgccaca gcctagcggg ctgacatcca
     8941 gacgcttaag cgcatcctgc aaacggcttt catcacgcgc cagcatctca acataggcca
     9001 ggcaccagtg cgcgaacgtc accggctggg cgcgttgcag gtgagtgtaa cctggcatta
     9061 ccgcgtcctg attgttttgt gcggtttcca ccagcgccga ttgcagctgc cggttagccg
     9121 tcagtaactc gctaacggta tctttgcacc acagtttcag gtcagtcgct acctgatcat
     9181 tacggctacg cccggtatgc agctttttgc ctaactggcc cactttgtcg atcagtttgc
     9241 cttccaccca gctatggata tcttcggcgt cgctttcaag gatttgttgt ggcctggcgc
     9301 gaacatcttc cagcaacacg ttcagcgcct cttccagttg cgcctgctct tctgcggtta
     9361 acacgcctac cgtgaccagg gctttggacc aggccacaga gccaacaata tcctgctccg
     9421 ccagacggta atcaaagcgc agtgagtcgt tgaattgttt gaaccgttga tctgctgcct
     9481 gggtaaaacg cccgccccaa agtgccataa ctctgtttcc ttattttgaa attcaatgcc
     9541 ggaaagctgc gcctccggcc aacaaaactt aagctaaaat ccgcgtaccc atcggcatac
     9601 cgttaaacag tgccggaagc tgctccgcat gacgccagga ggcgatatct accggacggc
     9661 ccagcgtgcg ggccgcatcc agcgccgcgt tcactttcac tatcatgccg tcagtaataa
     9721 tgccctgctc aatcagttgt tctgctttcg cggcggtcat ttcggcaatg cgttgccctt
     9781 tgccgtcgag aatgccgctg acgtcggaga gcaaaatcag atccgcgccc agcgttgccg
     9841 ccagcgccgt tgccgcctgg tcggcattga cgttcatcag ttgcccttcg tctgttacgc
     9901 caatggagct gaccaccggc agataaccgt tctccagcaa ggagttgata agcttaggcg
     9961 aacctggctg cgccagtcca acatgaccta actcttcatc aagctgggtc actttgacgc
    10021 tgtcgccgtc accgagaaac aaacctacgg ccgcaatctg atgtttcttc gcccatgcca
    10081 acagggtttt atttgccgtt cccgccagtg ctccggtgat aatgtctatc tgatcagcag
    10141 gcgtcacccg caggccgttt ttctttttca ccggcagatt cagccctttc atcagctcat
    10201 ccaccacgca accgccgccg tgcacaatca ccagcggacg ctgatgtgac tcacgataat
    10261 tcaccagtgc gctaaacaga cgttccagcg cctcttcact atccagcagt acgccgccca
    10321 gtttgataat taatggattc atcattgcac ccttaaataa gagactgcgt ttccgcatag
    10381 ccgaaacgaa tattggcgca ctgtaccgct tgtgccgccg cgcctttcag taagttgtct
    10441 tcggtcgcca caataatcag atgctcgccc tgaacggcaa acccgatatc gcaaaatggc
    10501 agcccaacga catttttcag cgccggaacg cctttgtcat acagccgcac cagcggttta
    10561 tgggcatacg cctgctgtaa cacttgcgcg acttgcgcct gggtcacacc cgatttcagg
    10621 cggcaggtaa tggtttcgag aatgccgcgc gggaaattgc ccagatgtgg ggtgaagata
    10681 acgtcagcac cgaggtgtgt ggcgatctct ggttgatggc gatgagtaaa gacgccatac
    10741 ggttgcaggc taacttcaca aaagctgttt gaaatggccg ctttacgccc tgcaccgctc
    10801 acgccgctgg tggcgttgat caccggccac tgattgaggt caagaagatc ggcatcaatc
    10861 aacggtttca gcgccagctg tgccgccgtc ggataacagc ccggcaccgc aatcaaattc
    10921 gcttctttta atttattacc gcaccactcc gccagaccgt aggctgcctg ttccaacagt
    10981 tccgggtatt gatgggtaaa gccgtaatat ttttcataga aggtggcgtc gttaacacga
    11041 aacgcgccgg aaaggtcgaa caccacgcag cccgcttcaa gaaactgcgg cgctaaatcg
    11101 tggctaactt catgggcggt ggcgagaaac actacgtcca cccctgggct aaactcgctg
    11161 atatccgaca tcggctgcaa cggcagatca acgatgcctt ttagctgcgg atgcaaatcg
    11221 gagattaact ttcccgcatc attgctttgc gctgaaacag tcaaagcggt tatgttcata
    11281 tgcggatggc gatttacata ggtcactagc tctgcgccag cgtagccgct ggcacccaca
    11341 atcagcgtat tcaacatcgg ggctattcac cttcttatgt ctggttgcta ggttaaacgt
    11401 aaaacattca ccttacggct ggtgggtttt attacgctca acgttagtgt atttttattc
    11461 ataaatactg catgaatatt gatactatca tgaccagagg tgtgtcaaca atgaaaaaca
    11521 aattaccgcc atttatcgag atttaccgcg ctctgattgc cacaccttca ataagcgcca
    11581 cggaagaggc actcgatcaa agcaatgcag atttaatcac tctgctggcg gactggttta
    11641 aagatttggg cttcaatgtg gaagtgcagc ctgttccagg aactcgcaac aaattcaata
    11701 tgctggcaag tatcggacag ggggctggcg gcttgttgct ggcggggcat accgatacgg
    11761 tgccatttga tgacggtcgc tggacgcgcg atccgtttac actgacggag catgacggca
    11821 agctttacgg cttaggcacc gccgacatga aaggcttttt tgcgtttatc cttgatgcgc
    11881 tacgcgatgt cgacgtcacg aaactgaaaa aaccgctcta cattctggcg actgctgatg
    11941 aagaaaccag tatggccgga gcgcgttatt ttgccgaaac taccgccctg cgcccggatt
    12001 gcgccatcat tggcgaaccg acgtcactac aaccggtacg cgcacataaa ggtcatatct
    12061 ctaacgccat ccgtattcag ggccagtcgg ggcactccag cgatccagca cgcggagtta
    12121 acgctatcga actaatgcac gacgccatcg ggcatatttt gcaattgcgc gataacctga
    12181 aagaacgtta tcactacgaa gcgtttaccg tgccataccc tacgctcaac ctcgggcata
    12241 ttcacggtgg cgacgcttct aaccgtattt gcgcttgctg tgagttgcat atggatattc
    12301 gtccgctgcc tggcatgaca ctcaatgaac ttaatggttt gctcaacgat gcattggctc
    12361 cggtgagcga acgctggccg ggtcgtctga cggtcgacga gctgcatccg ccgatccctg
    12421 gctatgaatg cccaccgaat catcaactgg ttgaagtggt tgagaaattg ctcggagcaa
    12481 aaaccgaagt ggtgaactac tgtaccgaag cgccgtttat tcaaacgtta tgcccgacgc
    12541 tggtgttggg gcctggctca attaatcagg ctcatcaacc tgatgaatat ctggaaacac
    12601 ggtttatcaa gcccacccgc gaactgataa cccaggtaat tcaccatttt tgctggcatt
    12661 aaaacgtagg ccggataagg cgctcgcgcc gcatccggcg ctgttgccaa actccagtgc
    12721 cgcaataatg tcggatgcga tgcttgcgca tcttatccga cctacagtga ctcaaacgat
    12781 gcccaaccgt aggccggata aggcgctcgc gccgcatccg gcactgttgc caaactccag
    12841 tgccgcaata atgtcggatg cgatacttgc gcatcttatc cgacctacac ctttggtgtt
    12901 acttggggcg attttttaac atttccataa gttacgctta tttaaagcgt cgtgaattta
    12961 atgacgtaaa ttcctgctat ttattcgttt gctgaagcga tttcgcagca tttgacgtca
    13021 ccgcttttac gtggctttat aaaagacgac gaaaagcaaa gcccgagcat attcgcgcca
    13081 atgcgacgtg aaggatacag ggctatcaaa cgataagatg gggtgtctgg ggtaatatga
    13141 acgaacaata ttccgcattg cgtagtaatg tcagtatgct cggcaaagtg ctgggagaaa
    13201 ccatcaagga tgcgttggga gaacacattc ttgaacgcgt agaaactatc cgtaagttgt
    13261 cgaaatcttc acgcgctggc aatgatgcta accgccagga gttgctcacc accttacaaa
    13321 atttgtcgaa cgacgagctg ctgcccgttg cgcgtgcgtt tagtcagttc ctgaacctgg
    13381 ccaacaccgc cgagcaatac cacagcattt cgccgaaagg cgaagctgcc agcaacccgg
    13441 aagtgatcgc ccgcaccctg cgtaaactga aaaaccagcc ggaactgagc gaagacacca
    13501 tcaaaaaagc agtggaatcg ctgtcgctgg aactggtcct cacggctcac ccaaccgaaa
    13561 ttacccgtcg tacactgatc cacaaaatgg tggaagtgaa cgcctgttta aaacagctcg
    13621 ataacaaaga tatcgctgac tacgaacaca accagctgat gcgtcgcctg cgccagttga
    13681 tcgcccagtc atggcatacc gatgaaatcc gtaagctgcg tccaagcccg gtagatgaag
    13741 ccaaatgggg ctttgccgta gtggaaaaca gcctgtggca aggcgtacca aattacctgc
    13801 gcgaactgaa cgaacaactg gaagagaacc tcggctacaa actgcccgtc gaatttgttc
    13861 cggtccgttt tacttcgtgg atgggcggcg accgcgacgg caacccgaac gtcactgccg
    13921 atatcacccg ccacgtcctg ctactcagcc gctggaaagc caccgatttg ttcctgaaag
    13981 atattcaggt gctggtttct gaactgtcga tggttgaagc gacccctgaa ctgctggcgc
    14041 tggttggcga agaaggtgcc gcagaaccgt atcgctatct gatgaaaaac ctgcgttctc
    14101 gcctgatggc gacacaggca tggctggaag cgcgcctgaa aggcgaagaa ctgccaaaac
    14161 cagaaggcct gctgacacaa aacgaagaac tgtgggaacc gctctacgct tgctaccagt
    14221 cacttcaggc gtgtggcatg ggtattatcg ccaacggcga tctgctcgac accctgcgcc
    14281 gcgtgaaatg tttcggcgta ccgctggtcc gtattgatat ccgtcaggag agcacgcgtc
    14341 ataccgaagc gctgggcgag ctgacccgct acctcggtat cggcgactac gaaagctggt
    14401 cagaggccga caaacaggcg ttcctgatcc gcgaactgaa ctccaaacgt ccgcttctgc
    14461 cgcgcaactg gcaaccaagc gccgaaacgc gcgaagtgct cgatacctgc caggtgattg
    14521 ccgaagcacc gcaaggctcc attgccgcct acgtgatctc gatggcgaaa acgccgtccg
    14581 acgtactggc tgtccacctg ctgctgaaag aagcgggtat cgggtttgcg atgccggttg
    14641 ctccgctgtt tgaaaccctc gatgatctga acaacgccaa cgatgtcatg acccagctgc
    14701 tcaatattga ctggtatcgt ggcctgattc agggcaaaca gatggtgatg attggctatt
    14761 ccgactcagc aaaagatgcg ggagtgatgg cagcttcctg ggcgcaatat caggcacagg
    14821 atgcattaat caaaacctgc gaaaaagcgg gtattgagct gacgttgttc cacggtcgcg
    14881 gcggttccat tggtcgcggc ggcgcacctg ctcatgcggc gctgctgtca caaccgccag
    14941 gaagcctgaa aggcggcctg cgcgtaaccg aacagggcga gatgatccgc tttaaatatg
    15001 gtctgccaga aatcaccgtc agcagcctgt cgctttatac cggggcgatt ctggaagcca
    15061 acctgctgcc accgccggag ccgaaagaga gctggcgtcg cattatggat gaactgtcag
    15121 tcatctcctg cgatgtctac cgcggctacg tacgtgaaaa caaagatttt gtgccttact
    15181 tccgctccgc tacgccggaa caagaactgg gcaaactgcc gttgggttca cgtccggcga
    15241 aacgtcgccc aaccggcggc gtcgagtcac tacgcgccat tccgtggatc ttcgcctgga
    15301 cgcaaaaccg tctgatgctc cccgcctggc tgggtgcagg tacggcgctg caaaaagtgg
    15361 tcgaagacgg caaacagagc gagctggagg ctatgtgccg cgattggcca ttcttctcga
    15421 cgcgtctcgg catgctggag atggtcttcg ccaaagcaga cctgtggctg gcggaatact
    15481 atgaccaacg cctggtagac aaagcactgt ggccgttagg taaagagtta cgcaacctgc
    15541 aagaagaaga catcaaagtg gtgctggcga ttgccaacga ttcccatctg atggccgatc
    15601 tgccgtggat tgcagagtct attcagctac ggaatattta caccgacccg ctgaacgtat
    15661 tgcaggccga gttgctgcac cgctcccgcc aggcagaaaa agaaggccag gaaccggatc
    15721 ctcgcgtcga acaagcgtta atggtcacta ttgccgggat tgcggcaggt atgcgtaata
    15781 ccggctaatc ttcctcttct gcaaaccctc gtgcttttgc gcgagggttt tctgaaatac
    15841 ttctgttcta acaccctcgt tttcaatata tttctgtctg cattttattc aaattctgaa
    15901 tataccttca gatatcctta aggaattgtc gttacattcg gcgatatttt ttcaagacag
    15961 gttcttacta tgcattccac agaagtccag gctaaacctc tttttagctg gaaagccctg
    16021 ggttgggcac tgctctactt ttggtttttc tctactctgc tacaggccat tatttacatc
    16081 agtggttata gtggcactaa cggcattcgc gactcgctgt tattcagttc gctgtggttg
    16141 atcccggtat tcctctttcc gaagcggatt aaaattattg ccgcagtaat cggcgtggtg
    16201 ctatgggcgg cctctctggc ggcgctgtgc tactacgtca tctacggtca ggagttctcg
    16261 cagagcgttc tgtttgtgat gttcgaaacc aacaccaacg aagccagcga gtatttaagc
    16321 cagtatttca gcctgaaaat tgtgcttatc gcgctggcct atacggcggt ggcagttctg
    16381 ctgtggacac gcctgcgccc ggtctatatt ccaaagccgt ggcgttatgt tgtctctttt
    16441 gccctgcttt atggcttgat tctgcatccg atcgccatga atacgtttat caaaaacaag
    16501 ccgtttgaga aaacgttgga taacctggcc tcgcgtatgg agcctgccgc accgtggcaa
    16561 ttcctgaccg gctattatca gtatcgtcag caactaaact cgctaacaaa gttactgaat
    16621 gaaaataatg ccttgccgcc actggctaat ttcaaagatg aatcgggtaa cgaaccgcgc
    16681 actttagtgc tggtgattgg cgagtcgacc cagcgcggac gcatgagtct gtacggttat
    16741 ccgcgtgaaa ccacgccgga gctggatgcg ctgcataaaa ccgatccgaa tctgaccgtg
    16801 tttaataacg tagttacgtc tcgtccgtac accattgaaa tcctgcaaca ggcgctgacc
    16861 tttgccaatg aaaagaaccc ggatctgtat ctgacgcagc cgtcgctgat gaacatgatg
    16921 aaacaggcgg gttataaaac cttctggatc accaaccagc agacgatgac cgcccgcaat
    16981 accatgctga cggtattttc gcgccagacc gacaagcagt actacatgaa ccagcaacgt
    17041 acgcagagtg cgcgtgaata cgacaccaac gtgctgaagc cgttccagga agtgctgaat
    17101 gaccctgcgc cgaagaaact gatcattgtt catctgctgg gtacgcatat caaatacaaa
    17161 taccgctacc cggaaaatca gggcaagttt gatggcaata ccgatcatgt tccgccggga
    17221 ttaaacgcgg aagagctgga gtcatataac gattatgaca acgctaacct gtataacgat
    17281 catgtggttg ccagcctgat taaagacttt aaagcagcaa acccgaacgg tttcctggtt
    17341 tatttctctg accacggtga agaggtttac gacacgccgc cgcacaaaac tcaggggcgt
    17401 aatgaggaca acccgacgcg tcatatgtac accattccgt tcctgctgtg gacgtcagaa
    17461 aaatggcaag cgactcatcc ccgtgatttc tcgcaggatg ttgatcgtaa atacagcctg
    17521 gcggaactga tccacacctg gtcagatttg gcgggcttat cttacgacgg ttacgatcca
    17581 acccgttcag tggtgaatcc gcagttcaaa gaaactaccc gctggattgg taacccgtat
    17641 aagaaaaacg cactgatcga ttacgacaca ctgccctatg gcgatcaggt gggtaatcag
    17701 taattatcag ccaggcgcta tttgccggat gcgacgcttg acgcgtctta tccggcctac
    17761 agatcgcggc ggtaggctgg ataaggcgtt tacgccacat ccggcaatac aactgccgca
    17821 atgtttacat cgaactcccc tcaggccaca cttttcaggt ggcctttttt aataatgcca
    17881 gttactgttt tcccgtctac atacctaagg gaataacatg tatcacgacg tcagctatct
    17941 gctctcccgc ctgatcaacg gcccgctgtc cctgcgccag atttactttg ccagcagtaa
    18001 cggcccggtg cccgatcttg cgtatcaggt cgattttcca cggctggaaa ttgtgctgga
    18061 aggtgagttt gttgataccg gcgctggagc aacgttagtt cccggcgatg tgctgtacgt
    18121 tcctgctggt ggctggaatt ttccacaatg gcaagccccc gctactacct ttagcgtgct
    18181 gtttggcaaa cagcaactcg gcttcagcgt cgtgcaatgg gatggcaaac aatatcaaaa
    18241 tctggcgaag caacacgtcg cccgacgcgg cccacgcata ggttcttttc tgctacaaac
    18301 gctcaatgaa atgcaaatgc agccgcagga gcagcaaacg gcaaggctta tcgtcgccag
    18361 cctgcttagc cactgccgcg atttgcttgg cagccaaatc cagaccgcct cacgcagcca
    18421 ggcactattt gaagctattc gcgattatat cgacgaacgc tatgcctccg cgcttacccg
    18481 cgaatctgtt gcacaggcgt tttatatttc gccaaattac ctctcgcacc tgtttcaaaa
    18541 aacgggggcc attggtttta acgaatacct gaatcacacg cgactggagc acgctaagac
    18601 gttattgaaa ggctatgacc tgaaggtaaa agaagtggcg cacgcctgcg gctttgtcga
    18661 cagcaactac ttctgccgtc tgtttcgtaa aaacaccgaa cgctcgccgt cggaatatcg
    18721 ccggcagtac cacagccaac tgacagaaaa accgactact ccagaataag atgggtttgc
    18781 tgcggcgcag aaagcacttt gcgcaccgcg ctcattaccc gctgcggctc acgcaggaat
    18841 gcgtagatgc tgcattgcac atagcggcaa tgttcaaatc gctcggcacc ggcaagctcg
    18901 atatccgtaa tcaacagagc aacatccgcc cggcggatat cctcatccgc taaacgattc
    18961 tccgttccca gcgcgccctg agtttcaatg ctgactcccc acttctctaa caggcacaac
    19021 ttttccagcc gttccgccgc catataagta tgcgccacgc cgcttacgca ggcggttact
    19081 gccaccaggt atgccatttt aacctcccac ggtaacctga agtccggccc gttctgccat
    19141 ttcgcgcatc gttgccacat cagctgacga cggcgcaggc acctctttca tcgaccatgt
    19201 tttccccagc aggcggtatt tcggttcgcc gtactgatga aacggtaaca gatggatctg
    19261 cctgatattc agcgggatca gtacatccag cgcctgctgc atattctccc ggctgagcgt
    19321 gaaaccaggg atcagcggta aacgcgggat cacgttgacg ccctcactca ccagcaaacg
    19381 cagattctcc agcacgcgtg gcaggttcat cttcaccaca tcccgcgcct gagtcgcgtc
    19441 cataattttt aaatcgaaca acacttcatc gcacaatttc gccagcggta atagcttgct
    19501 ggctggtgcg tctccggcag tttcaatggc gcatgacaca ccccacagcc gcagtcgctg
    19561 taaaaaacgg gtagcaaact ccgcctgcat taacacttcg ccgccagaaa gcgtgacgcc
    19621 gccgccggac gtgcgaaaga aaatgtcatc tttcatcact tcccgttcca gagcgtcaag
    19681 gctgatatcg cgaccaatcc gttcaaacgc cccggagggg cattcatccg catcacgcaa
    19741 acatttcgca cagtgcagac atttcgcctc tctgcgtacc gtctggattt tgccggagat
    19801 cgactccgga ttagcacacc acgggcaaag atgcggacag cctttaaaaa agaccaccgt
    19861 acgaatgccc tcgccgtcat tcagtgaata acgctgaatg ttgaaaatgc gcgccacatc
    19921 atcgcggcgc gtttccacaa cgttacagct gatgcgctgt ccggcggatg atgtcatcct
    19981 ggatctcctt cgacagttcg acaaagaagg cgctgtatcc ggcaacgcgc accaccagcc
    20041 cggcataatc ttgtgggcgc tgttgcgctt cccgcaacgt gtcggcgttc accacgttaa
    20101 actgaatatg ttgtaactta agctgggtaa acgcccgtaa gaagtcggcc agtttgcgta
    20161 atcctgcttc accttccagg gtcgccggag tgaatttcac gttcagcaac gtaccgttag
    20221 acagcagcgt gttatcgagc ttactgactg acttcagtac cgctgttggc ccttgtgcgt
    20281 cctggcccag catgggtgac aagccgccgt ctgccagctg ttctccggca aaacgaccgt
    20341 ctggcgtcgc gccaaccacc gatcccaacg ggacgtgagc agaaacggta tacgatcccg
    20401 gcgtgaagta gccgccgcgc gggttctggt atttttccac ttctttgcag tagtggcgca
    20461 acagttcggc gctgatgtta tccacctcgt cgatatcgtt accgtatttc tcgaagcggt
    20521 taattaagcg agcgcggact ttttcgcctt ctggcgttgc gaagttggct tttaataccg
    20581 acagcaattc gtcaaaactt aaacgctgtt gctcaaaaac catccctttc aacgcatgga
    20641 gagaatcgct caggttggcg ataccgatcc cctgtacgcc ggagaagtta taacgcgcgc
    20701 cgccatcggt aatatcgcgg cctttttcca gacaatcgct gataaacgat gagagcagcg
    20761 gtacaggtgc ccagtcgcga tggccgatat cacaaatatt gctgccctca accatcaggg
    20821 tgatgtagtg gctgatcttg gcgcggatct gctccagtaa accttcataa gtcagcgcag
    20881 cattgccttc attttcatgc aggcagattt ccatcacttt cagcagatta aacatcgcga
    20941 tgtcatgcaa gccgtaggtt ctgccgggaa tagataattc cacacagccc actacggaat
    21001 agtcgcgcgc atcttccagc gaaacgccac ggttgaggaa cgctggcacc accacttcat
    21061 cgttaaagat ttgcggaata ccggtgccga agcgaatggt ttcggcggtt ttcatcagga
    21121 acggcgtgtc gatcaaggcg ttagtgcgca cgccgaggtt cggttgcggt aattgcacgc
    21181 tttgataggc gtcaaggcaa aggaacgaaa gcacgttcac cgcgctacgt ccgttctcgg
    21241 ttaacccgcc gagcagtgcg gtatagccgg tcgggaaacc ggcgaaataa cgcgcgctac
    21301 tggtggagcg caacagcacg atgtcgttgc atttcaccca taaagattcg agcagttctt
    21361 tcaggaacgc cgcatcttcg ccctgggtta atgatgtctg atagaacggc aacatatact
    21421 ggtcgaagcg ccctaacgat agcgaactgg cgttggattc gtattgcaga atgatgttca
    21481 tgtaccagaa taactggcac gcctgccaga acgtctgcgg cttatgttgc gcgttatggc
    21541 gggagatctc tgcaatagtc agcagctctt cgcgacgctg ggcatctgtg cagtttgccg
    21601 ccatcgtttc cgccagttcg gcgtaacgca aaatgtgttt ctgcgaggct tccagcagta
    21661 acaacgcggc ctgataaaag tgattctccg gctgttgctg acaatgttgc tgcatctgtg
    21721 ccaccagctc acccagcccg tgattcaaca ggcgtgggta atcaataata atgtgcccct
    21781 ggcctttatc cgtctggttg atgctgaaaa tctgcgtgtt ggtcgcggct tttacttcat
    21841 ctgtcatctg cccgttgatg aaatctttca tcgaacgttt ttcccagtac gggaacaact
    21901 cttcacggta gatacgttta tcttcttcgc tgatagcaaa gcggtcctgc ggacgcgtcg
    21961 ggaattgatc cagctctttc agcagccagt aagggtccat ttccggcgac ataatcccgg
    22021 cgcgcggttt tacggtgcgg ttaccggcaa tcagttcttc atcacgaatc gaaatttcaa
    22081 catgttcaag gatatactct gttgctttcg cccggcgcaa tatcaccggt tcgccttcgg
    22141 tttgccgatg gctggcggta taaagcagcg cccgctccag cgagatttca cgggtattgg
    22201 caaacagtgc agttttgagg cgagagatac gattcgtcat gaggaactcc tgtgggaaag
    22261 cgaacccgcc cttgcgagcg ggagaagaac ttaagcggtt tgcgccaggt gagcttcaat
    22321 tttgctcata atggcgtcag cacgttttac tgcatcgctg atgttgacgc gcacgatggt
    22381 cttgccagca aaacgctctt caaacttgat gccgatatct ttggtcagaa tcaccatatc
    22441 agcgctcgcc acatcttccg cagtcagttc attttccaga ccaattgacc cctgggtttc
    22501 tactttcact tcccagcctt tcgctttcgc ggcactttcc agcgcctctg ctgccatata
    22561 ggtatgggca acacctgaag gacatgcggt tactgcaata attttcgtca tggctcgttc
    22621 ctcaattaat taatttcaaa atccaaatcc aggtcgtctt ctttttcatc agtcgaagac
    22681 ccatttttac gcgccagact tttcagcacg ttcacacaaa cagccgtcac cactgctccg
    22741 acagccactg ctgcgatata acccagcttg ccttcaacca ccggcagcac aatcagacca
    22801 ccccagcctg catagcactg cgcaccgacc agcgccgcag ttactgcacc acaaactgaa
    22861 ccgaccatga tggaaggaat gacacgcagc ggatcggcag cggcgaaagg aatcgcccct
    22921 tcagtaacgc caacacagcc catcaccagt gccgctttgc cggtttcgcg ctcttctgcg
    22981 gagaaatttt tacgaccaat cagcgtcgcc agccccatcc ccagcggcgg gatacaaata
    23041 cccacggcag cgatggccac cacggtataa acaccctgag caacgcaaat cagcatgaag
    23101 gcataggcca ctttgttaac cggaccgccc atatcgaacg ccagcatcag acccatgatc
    23161 accgccagca taacaatgct gccctgctgc atcccctgaa gccactgagt caggctgttg
    23221 gtcaacgccc ctacaggctc gcccaagccc cacatcatga tgcctgcggt aatcagtgtg
    23281 ccgacgatag gaataatgaa gataggcatc accgagcgca gaactttatg caccggaatt
    23341 ttcttcaggt aatgcaccac gatgccgccg ataatcccgg cgatcagtgc accaaagaag
    23401 cccgcaccaa agctgttacc aacccaggca ccgatagcgc acggagccag cgcagaacgc
    23461 tctgcaatgg aataaccgat gtacgctgcg aggaaaggca ccatcagcgt caagcccgca
    23521 acgccgatat caaacagttt tttcagattt ggatcggcta cggcatccgg cactgcgcct
    23581 ttgccataca acatgacgga aaccgccagc aaaataccgc ccgataccac gaagggaatc
    23641 atgtgtgaaa cgcccgtcat taaatgctga cgggtatttt tcaggatctg caccaactca
    23701 ttcataagct gctcccgggc ttgcgaaagc ccatgtccat atttttgatg gaggaaacaa
    23761 taggcaatcg caggcggagc aaacagtgga taaaaaggcc atttactgga cttttgtaat
    23821 atcagtacaa aaatgcgatc cgcctcataa cttgcgataa accggaagca tgccgcaaaa
    23881 cagcgtcttg tgagacgcgt cgcaaattga cggttacatt acatttgtcc agcttttggc
    23941 agatttgtca catggcaggc cgttgccgtg cgctcttatc ctgtaaacag aaaaccgtac
    24001 cgggagagag gcaatggccc tgattgtgga atttatttgt gagctaccta acggcgtaca
    24061 tgcgcgtccg gcaagccacg ttgaaacgct gtgtaatact ttttcatcac aaattgagtg
    24121 gcataacctg cgcactgacc gcaagggcaa cgccaaaagc gcccttgcgc tgattggcac
    24181 cgatacgctg gcgggcgata actgccagtt actgatttcc ggggccgacg aacaggaagc
    24241 gcaccagcgt ttaagccaat ggctgcgcga tgaattcccc cactgcgatg cgccgctggc
    24301 ggaagttaaa tctgacgaac tggaaccact gccggtttca ctgaccaatc tgaatccgca
    24361 aattatccgc gcccgcaccg tgtgcagcgg tagtgcaggc ggcattctga cgccgatctc
    24421 ttctttagat ctcaatgcgc tgggtaatct tcccgcagcc aaaggcgttg acgccgagca
    24481 atccgcactg gaaaacggcc tgacgctggt actgaaaaac attgagtttc gtctgctgga
    24541 tagcgacggt gctaccagcg cgattctgga agctcaccga tccctggctg gcgatacttc
    24601 cctgcgcgaa catttactgg caggcgtcag cgccggatta agctgcgccg aagcaattgt
    24661 tgccagcgcg aatcactttt gcgaagagtt ttcccgttcc agcagcagct acctgcaaga
    24721 acgtgccctg gacgtacgcg acgtctgctt ccagttactc cagcaaatct acggtgagca
    24781 acgcttcccg gcaccgggaa aactgacgca gcccgccatt tgtatggctg atgaactgac
    24841 ccccagccag ttcctcgaac tggataaaaa tcacctcaaa ggattgttgc tcaaaagcgg
    24901 cggcaccacc tcacatacgg tgatccttgc ccgttcgttc aacattccaa cgctggttgg
    24961 tgtggatatt gatgccctta ctccgtggca gcaacaaacg atttatatcg acggcaacgc
    25021 cggggcgatt gtggttgagc caggggaagc cgtagctcgt tattatcagc aagaagcccg
    25081 cgtacaggac gccctgcgtg agcaacagcg tgtctggctg acccaacaag cccgtaccgc
    25141 tgacggtatc cgcattgaaa ttgccgctaa catcgctcac tccgtggaag cgcaggccgc
    25201 attcggcaat ggtgcggaag gcgttggttt gttccgcact gaaatgctct atatggatcg
    25261 caccagcgca ccgggcgaaa gcgagttgta caacattttt tgtcaggcgc tggaatccgc
    25321 caacggacgc agcattattg tgcgcactat ggacattggc ggcgacaaac ccgttgatta
    25381 tctgaacatt cccgcagagg caaacccgtt cctcggttat cgcgccgtgc gtatttatga
    25441 agagtacgcg tcgttgttta ccacgcagct acggtcgatc ctccgcgcct ccgctcacgg
    25501 cagcctgaaa atcatgatcc cgatgatctc ctcaatggaa gagatcttat gggtgaaaga
    25561 aaaactggcg gaagccaaac agcaactacg taacgaacac attccgtttg atgagaaaat
    25621 ccagctcggc atcatgctgg aagtgccgtc ggtgatgttc atcatcgatc aatgctgcga
    25681 agagattgat ttctttagta ttggtagtaa tgacctgacg caatatctgc tggcagtgga
    25741 tcgcgataac gctaaggtta ctcgtcacta caacagcctg aatccggcat tcttgcgggc
    25801 gctcgattac gccgtgcaag cggtgcatcg ccagggcaaa tggattggtc tgtgcggtga
    25861 gctgggagcg aaaggttccg tgctgccgtt gctggtcggc ttagggctgg atgaactcag
    25921 catgagcgca ccatcaattc cggcggcgaa agctcggatg gcgcaacttg atagccgtga
    25981 gtgccgcaag ttgctcaacc aggcaatggc ctgccgtact tcgctggaag tggaacacct
    26041 gctggcgcaa ttccgcatga cccaacaaga cgcaccgctg gtcaccgccg agtgcatcac
    26101 actggaaagc gactggcgca gcaaagaaga agtgctcaaa ggcatgaccg ataacctgct
    26161 gctggcgggc cgctgccgct atccgcgtaa actggaagcc gacttgtggg cgcgcgaggc
    26221 cgttttctct accggtctgg gctttagttt tgccattcca cacagcaaat cagaacacat
    26281 tgagcaatcc accatcagcg tggcgcgtct gcaagcgccg gtgcgctggg gcgatgatga
    26341 agcgcaattc atcattatgt taaccctgaa caaacacgct gcgggcgatc agcatatgcg
    26401 cattttctcg cgcctcgctc gccgcatcat gcacgaagaa ttccgtaacg cgctggttaa
    26461 cgccgcctct gccgacgcta tcgccagcct gctgcaacat gaactggaac tgtaaaagga
    26521 aacatcatgg aactgtatct ggacaccgct aacgtcgcag aagtcgaacg tctggcacgc
    26581 atattcccca ttgccggggt gacaactaac ccgagcatta tcgctgccag caaggagtcc
    26641 atatgggaag tgctgccgcg tctgcaaaaa gcgattggtg atgagggcat tctgtttgct
    26701 cagaccatga gccgcgacgc gcaggggatg gtggaagaag cgaagcgcct gcgcgacgct
    26761 attccgggta ttgtggtgaa aatcccggtg acttccgaag gtctggcagc aattaaaata
    26821 ctgaaaaaag agggtattac tacacttggc actgctgtat atagcgccgc acaagggtta
    26881 ttagccgcac tggcaggggc aaaatacgtt gctccgtatg ttaaccgcgt agatgcccag
    26941 ggcggagacg gcattcgtac ggttcaggag ctgcaaacgc tgttagaaat gcacgcgcca
    27001 gaaagcatgg tgctggcagc cagctttaaa acgccgcgtc aggcgctgga ctgtttactg
    27061 gcaggatgtg aatccatcac cctgccctta gatgtagcgc aacaaatgct caacacccct
    27121 gcggtagagt cagctataga gaagttcgaa cacgactgga atgccgcatt tggcactact
    27181 catctctaaa ggagcaatta tggaccgcat tattcaatca ccgggtaaat acatccaggg
    27241 cgctgatgtg attaatcgtc tgggcgaata cctgaagccg ctggcagaac gctggttagt
    27301 ggtgggtgac aaatttgttt taggttttgc tcaatccact gtcgagaaaa gctttaaaga
    27361 tgctggactg gtagtagaaa ttgcgccgtt tggcggtgaa tgttcgcaaa atgagatcga
    27421 ccgtctgcgt ggcatcgcgg agactgcgca gtgtggcgca attctcggta tcggtggcgg
    27481 aaaaaccctc gatactgcca aagcactggc acatttcatg ggtgttccgg tagcgatcgc
    27541 accgactatc gcctctaccg atgcaccgtg cagcgcattg tctgttatct acaccgatga
    27601 gggtgagttt gaccgctatc tgctgttgcc aaataacccg aatatggtca ttgtcgacac
    27661 caaaatcgtc gctggcgcac ctgcacgtct gttagcggcg ggtatcggcg atgcgctggc
    27721 aacctggttt gaagcgcgtg cctgctctcg tagcggcgcg accaccatgg cgggcggcaa
    27781 gtgcacccag gctgcgctgg cactggctga actgtgctac aacaccctgc tggaagaagg
    27841 cgaaaaagcg atgcttgctg ccgaacagca tgtagtgact ccggcgctgg agcgcgtgat
    27901 tgaagcgaac acctatttga gcggtgttgg ttttgaaagt ggtggtctgg ctgcggcgca
    27961 cgcagtgcat aacggcctga ccgctatccc ggacgcgcat cactattatc acggtgaaaa
    28021 agtggcattc ggtacgctga cgcagctggt tctggaaaat gcgccggtgg aggaaatcga
    28081 aaccgtagct gcccttagcc atgcggtagg tttgccaata actctcgctc aactggatat
    28141 taaagaagat gtcccggcga aaatgcgaat tgtggcagaa gcggcatgtg cagaaggtga
    28201 aaccattcac aacatgcctg gcggcgcgac gccagatcag gtttacgccg ctctgctggt
    28261 agccgaccag tacggtcagc gtttcctgca agagtgggaa taacctactc caaactcccg
    28321 gcttgtccgg gagtttgaac gcaaaattgc ctgatgcgct acgcttatca ggcctacgca
    28381 atctctgcaa tatattgaat ttgcgtgctt ttgtaggccg gataaggcgt tcactccgca
    28441 tccggcactc tgtgccagta atctgaaact cccacgttgt tcaggaattt tttatccgct
    28501 tctggacatt ttctctacag aacaatcgtt agcccggaag gtcgaatctg tgactcttat
    28561 tttcacggac gaaccagatg aaagcttcac tggcgctgct cagcctgcta acggcattta
    28621 ccagccactc cttaaaatct cccgccgttc caccaaccgt ggtacaaatc caggccaata
    28681 ccaaccttgc catcgcagac ggtgccagac agcaaattgg cagcacgcta ttttacgatc
    28741 cggcgtatgt gcagcttact tatcctggcg gtgatgttcc gcaagaacgc ggtgtatgtt
    28801 ccgatgtggt gatccgcgca ttgcgcagcc agaaggtcga tttgcagaaa ctggttcacg
    28861 aagatatggc gaagaatttt gctgagtacc cgcaaaaatg gaagttaaag cgcccggaca
    28921 gcaacatcga tcaccgtcgg gtgcctaatc tggaaacctg gtttagccgc catgataaaa
    28981 cacgccccac cagcaagaac cccagtgact atcaagcggg cgatattgtc tcctggcgac
    29041 tggataacgg gctggcacat attggggtgg tttcagatgg cttcgcccgc gacggtacgc
    29101 cgctggtgat acataacatt ggcgcaggcg cgcaggaaga agatgtgctg tttaactggc
    29161 ggatggtggg gcattatcgt tattttgtta aataagagat cgccccacat gaagaaaaaa
    29221 ttcagatcct ttttacactg acggcttctt ttttcttacg gctcaccagc gccagtgcca
    29281 gcacaatcag cacaataccg ctaccttcaa cggcccccgg attctcgccg agcagccacc
    29341 aggaaaagag tacgccgcaa acgggaacgg ccagtgtgct taagctggca atactggcag
    29401 gcaagttttt caatacaaac aaccataagc tccacgccag tgccgtcgcc agaatcgcac
    29461 tgtaggccag cgcccagaac acggtgggct gccagtcaat ttcacgttgc ggcaccagta
    29521 aagcgaccac actcatcacc agcgccgcat acagcatctg ccaggatgtt aacgacaata
    29581 aatccacgcg cggatgacgg gcatacagac gtttagcaac aatcgcgctc gccccccaac
    29641 tgacgccgga gaggattgcc agcatggcac ttttcatcga agagaaatcg agttgccacg
    29701 gctgcaacac caaaaataag ccgaaagcgg caatcagaat cgcgaaatat tgcccacgtc
    29761 gcaggcgttc accgagaaac aacgcggcga aaatcaccac ccagaacggc atggtatagc
    29821 tcaggatcgc caccttcccc gcacctccgc tgaccaacgc ccactgcgcc agaccaacca
    29881 tcccgcaggt ttgtaacagg gcaatggcta aggtgtattt aaacggtgtc gggcgcattc
    29941 cgcgaccacg taataaaagg acgatgaata aaacgagagc gccgaaaatg cagcgtaagg
    30001 cggtaaagtc gaaggcaccg atgtaactgg tgacttgctt catgaaaatc cagctataac
    30061 tccagataag tgtgagcaca accaggccac tgattgccag tgggttgctc tttcctgcgg
    30121 cagacatgag agatccagtg tgtagttttc gttcgcccac tatacgctgg taaagaacgt
    30181 tcagcgactg ccagcaagca gccgctgaac ggggtcagat tacagcaggt cgaaacggtc
    30241 gaggttcatc actttcaccc atgccgccac gaagtcttta acaaacttct cgtgggcatc
    30301 gctactggcg taaacttccg ccaccgcacg caggacggag ttagaaccaa acaccagatc
    30361 cgcacggctg gccgtaaatt tcacttcgcc ggtttcacgg tcacggcctt cgaacagctc
    30421 tttcgattcg tcggtcgctt tccactcgta acgcatatcc agcaagttca cgaagaagtc
    30481 attgctcaat acgccaacgc ggtcagtgaa gacgccgttt ttgctgccat cgaagttggc
    30541 acccagtaca cgcatgccgc ccaccagcgc agtcatttcc ggcgcggtca gcgtcagttg
    30601 ctgtgctttg tcgatcagca gtgactcggt ggtggaaacg tccagacgag cgcgatagtt
    30661 acggaaaccg tcagcaattg gctccagcag ctcaaacatc tcaatgtcag tctgatcctg
    30721 acgcgcatca acgcgacccg gcgcaaacgg tacatgaatg ctcaaacctg cggcgcttgc
    30781 ggctttctca acaccaacca caccagccag cactatgata tccgccagcg aggctttacc
    30841 agactctttc tggattttct ccagaacagg cagagcacga acggctgcgg cgttcacatc
    30901 ccagtcgcgc tgcggcatta atgccagacg cgcaccgttg gcaccaccgc gtttgtcgcc
    30961 accacggaag gtagaagcag atgcccaggc caccgatacc agctcactaa cagacagacc
    31021 agaatccgca atcgcgaatt tcagatcgat aatgtcctgc tcggtcgggt tgtagatcgg
    31081 ctgcggcagc ggatcttgcc agatcagatc ttctttcggc acttccggcc cgatgtagcg
    31141 agatttcggc cccatatccc tgtgcgtcag tttgaaccag gcacgggcaa aggcttcgtt
    31201 gaacgcctgc ggatcgttga ggaaacgacg agagatcttc tcgaactcag gatcaaaacg
    31261 cagcgtcagg tcggtcacca gcattgtcgg tttacgtttc ttcgacggat caaacggatc
    31321 cgggataatt tccggtgcgt ctaccgcttc gaactggatt gcgccagccg ggctgcgggt
    31381 ctgtacccac tcatacttga acaggttctc gaagaaatag ttgctccact gggtcggcgt
    31441 ctgggtccag actacttcca gaccagaggt aatggcatct gcgccaacgc cgctgccgta
    31501 agtgctcgcc caacctaaac cttgttcttc aatcggtgca gcttctggat caggacctac
    31561 atttgatgtc ggaccggcac cgtgggtttt acccagcgta tgaccacccg caatcagcgc
    31621 cacggtttct tcgtcgttca tgcccatgtt gccgaaggtc gcgcggatag ctgctgccgc
    31681 agaaagcggt tcgccgctgt gatccgggcc ttccgggtta acgtaaatca gacccatctc
    31741 ggttgcaccc agcggtgctt tcgccagcgc ttccggatga cggtgagtca gccaggcttt
    31801 ttcatcaccc cagttaacat ccagatccgg ttcccagacg tcttcacgac cggcaccaaa
    31861 accgaaggta cggaagccgg agttttctag cgccacgtta cccgcgagga taaacaggtc
    31921 ggcccaggag attttctgac catatttctg tttgattggc cacaacaggc gacgcgcttt
    31981 atcgaggctt acgttatccg gccaggagtt cagcggtgca aaacgttgct gaccacgacc
    32041 cgcgccaccg cgtccatcga ttgaacggta agtccccgcg ccgtgccagg ccatacgaat
    32101 aaacagaccg gcgtaactgc cccagtcggc tggccaccac ggttgagatt ctgtcaacag
    32161 ggctttcaga tcttttttca ggccgtagta atctaatttg ctgaattctt tgcggtagtc
    32221 aaagtcctca cccagtggat tagaacgatt agaatgttgg tttaacaggt caacacgaag
    32281 ttgatttggc caccagtcgc gagtggttgt gcccgccccc gcactctggt cgtgaccgcc
    32341 ctgatggaac gggcatttgc cagtggctgt ggtgttatgg atatcgtctg acgtgctcat
    32401 caatgtgctc ccctctacag tgttaccgtt acgatacaca gcgttagaga gaagttataa
    32461 ttgaattaat ccacggatgc gatagttgag atcttacata ttgttggtta aagagatgta
    32521 gatcaaattg atcttaatta agcttttttg attatgtccg aattcggaca aatgctttat
    32581 aaaaaagggt tttagcttca tatccttcaa gtaatgaggg agaaaacaag gctgataacc
    32641 ttattttccc gccctcattt cgaggcagca ttttgtgctc tgtttaaaat ttgtgatcac
    32701 tgtgtgattt tcacaaaagc cacactattt ataaaccagg tcgaaccccc agcgtatggc
    32761 aaatcgcgta actcatttca gcacggttaa gcgtatagaa gtggaaatct ttcactcctt
    32821 cacggcttaa aatcttcacc atatccatgg caatattcgc gccaaccagt ttgcgggttt
    32881 cggcatcatc atccagaccg tcgaacattt gcgccatcca cgccggaata cgcacgttgg
    32941 tcatatcggc aaatttcttc gcctgtttaa agttagatac cggcaaaatt cccggaataa
    33001 tttccacatc aatgcccgcc gatacacagc ggtcacgaaa acgcaggtag ctttcgacat
    33061 cgaagaagaa ctgagtaatc gcgcggttgg ctccggcatc cactttgcgt ttcagattaa
    33121 gcaaatccgc ctgagcgctt tttgcttccg ggtgaacttc cggatacgcc gccacggaga
    33181 tatcgaaatc tgccacttct tttaacagcg tcaccaggtc agaagcatac atttctggct
    33241 taccacttcc cggcggcaga tcgccacgca gcgccacgat atgacgaata ccgttattcc
    33301 agtagtcgcg tgcaatggtg cgcagctcgt cgggcgtcgc atcaatgcaa gtaagatgcg
    33361 gtgccgcttc cagaccagtg cgatctttaa tgcctttaat aatgctgtgc gtacggtcgc
    33421 gctcgccgga gttcgcgcca taggtcaccg atacaaactt cggtttcagg ctgctaaggc
    33481 gatcgatgga gttccacagg gtctgctcca tttcactggt acgcggcggg aaaaactcga
    33541 acgaaacgtt aatctgcccc tggacttctg ccaggctctg attcagggca tcccgctggc
    33601 tggcgtgaaa aaagctcata ccttacctca tcaatcgctt gtagttatat gttgtgttgt
    33661 gcacatctat ccgtttagac gtccagatgt aaagatgaag gaaaagccga agggcgtcaa
    33721 ccgaaaaatg accaatgatg gtgaggaaaa atcagggaag atgaaaaaac ttcaggatgg
    33781 taagaaaaag aaaatccggt atgcaaagca aaccggactg caaatataaa ctaaccatgt
    33841 acttattgct tcttgccgga ttcgtcgtaa acgcttaatc cggcctaatc ctatgataat
    33901 tcaatatatt tcattagaaa ccataaaccc gaaaacatga gtaccgggca ttattaaatt
    33961 tctgaaatta caacaactgt gccagccggt tgatatccga ctgaatcgcc ccggcggtga
    34021 cgtcgcgccc agcgccaggt ccgcggatca ccagagggtt atcgcgatac cagcggcttt
    34081 cgatggcaaa gacgttatcg cacggcagca gtgatgccaa cggatgatct tcacgcaccg
    34141 cttccacgcc tacacgcgct ttaccgttgg catcgaaacg cgccacgtag cgcagcacca
    34201 gccccatttc gcgggccgct tccagccgtt gcaccatctg ctcgttcagt tcatcgccat
    34261 tttcaaagaa atggtcgatg ctgccgcctt cgcaatgagc aggcaccagc gattccacac
    34321 gtacctgatc cggttcgatg ttgtaacctg cttcacgcgc cagaatcacc agcttgcgca
    34381 tcacgtcttt gccagagaga tcgtcacgcg ggtcaggttc ggttaagccc tgctgccacg
    34441 cctgatccac cagctcggta aacggcacgc taccgtcgaa ttgcaggaac agccaggaga
    34501 gcgtgccgga gaagatcccg ctgatcgaca aaatagtatc gccgctgtcg atcagatcgc
    34561 gcacggtgtg gttgatcggc aagcccgcac cgacggtggc attgtacagc cagtgacgcc
    34621 cggttttttc gaaggcgtcg tggatctggc gatatttatt gctgtcgctg gctcccgcca
    34681 gtttgttggc gctgataacg tggaaaccgt ggctggcgaa atcaagatac tgatcagcaa
    34741 gctgctggct ggcggtaacg tccagcacca ctaaatcatc atacggatgg gcgcgcatcc
    34801 acaggaacaa cgactcttca tcctgctcaa ccgcttcatc gttgaagaag gctaacgcgc
    34861 ggctggcgtc cagcccgtca tagctcaaca ggctgcggcg gctgtccacc acacctgcca
    34921 gcacaaactc aaagccggta cgtgccgaaa gcgtgctctg ctcacgggcg aacagttcca
    34981 gccaacggga accgatattg cccttaccga acaataccag gccgatgcgt ttttctgcgc
    35041 ggaagacgga ctgatgcagc ccctgaatca ggctttcggt cgggccggtg cgcagtactg
    35101 ccaccaggct gatgccgtca tcggactgcc aggtaaattc gaccggctgg cctttcagtt
    35161 gctgccagaa gcggtggcaa tgcagcgggt tacgggtgac gcctgcaccg accatcgcca
    35221 ccagcgccag cccctgacgc aggcgcagtt cgccaggtaa tcccgcttcg tcgaggattt
    35281 tcagcgcact gtcggccact tctgaggtgt agcaaaattg cagcaactgg cgatcgttat
    35341 gtacgccaac cgccagcggg cgtacctgcg cgcgtttcag gatttggtcg atctctttat
    35401 gcgccagttt gaaatcctga ctggcgggca cctgaaactc aatcaaacag acatcatcgt
    35461 ggctggtgac aatacgcgca ccagtaccgg aggccagcac gcgttcaatg cgcgtggaac
    35521 cttgatccgg cgtgtagcta cagcgcagtt gcaggtcgat ttcgctgcca gaaaccggct
    35581 gtaaagtacg ggcgtgaaga acgggagccg ccaggcgcgc cagttcgctg gcctcatcca
    35641 gacgcagcaa cggcagcagg caggcatctt tcactttacg cgggtcggca ctgtataccc
    35701 cggcgacgtc gctccagatg gttacgcgag aaacacccgc cagcgcaccg atttgtgtcg
    35761 cggaatagtc ggaaccgtta cgccccagca gcaccgtttc accggcgttg ttgcggctga
    35821 taaatccggt caccaccaga cgtttgcccg gatgttgcac cagcagctgt tgcagcaacg
    35881 ggtaagaaag cccttcatca acctgcggtt gtgcggcgcg ttcagcgcgt aaaaactcgc
    35941 gggcatcaag ccaggccgct ggcagccctt gttgattaag taccgcagac atcagacgtg
    36001 ccgaccatac ttccccgtgg cccaccactt ccgcatacac tgcgtcgtta ataccgctgt
    36061 cgagcagcgc cgccaggcgc tcaaggtcgc tgacaaaagc gctaatgagg ctatcggctt
    36121 cttcagcggg tagcagaccg ctaatcagat cgcactgata gcgacgcagc gtttgttgaa
    36181 cctgatgcgc agagagacga tcggtctggc ttagtttcaa ccagttaatc aactggttag
    36241 tggtgctacc ggcggcggaa accaccatca tatcgtcagg ctgagagtac tccgccataa
    36301 tgcccgcgac acgcaaataa cacttcacat cagccagact actgccacca aatttatgca
    36361 gctgacgacc tttcgcccct gcctgcgcaa tcacactcat ttttacccct tgtttgcagc
    36421 ccggaagcca ttttccaggt cggcaattaa atcttcgcca tcttcaatac cggtggagat
    36481 acgcagcagc gtctcggaga tcccggcggc agcacgcgct tctggtgcca tgcctgcatg
    36541 tgtcatggtt gcggcgtgag agattaaact ttccactccc cctaatgatt ccgccagcgt
    36601 aaacaacgac agcccgccca ggaaacgacg cagcgtctgc tcatcgccat ccagttcaaa
    36661 actcaacatt gcgccaaagc ctttttgctg gcgcgcggca atttcatgcc cctgattttc
    36721 cggcaacgac gggtgataca gttttttcac caacggctgg gtttgcaggt atttcacaat
    36781 cgcctgcgcg ttgcgctgcg ccagctccat acgcggcacc agcgttcgca acccacgtag
    36841 cagcagatag ctgtcaaacg cgccgcccgt cacgccaata ttgtttgccc accaggccag
    36901 ttcagtgaca acgtccgggt ctttagcaat caccacgccg gccactacgt ctgagtgacc
    36961 gttcagatat ttcgtgcatg aatgcaacac cagatcggca cctaatgcca gcggattttg
    37021 taatgccggg cttaagaagg tgttatccac cacgctcacc gccccgactt cccttgccag
    37081 atggcagatt ttcgcaatat ccacgacgcg taacaatgga ttacttgggc tttctaccag
    37141 taccagtttg ggtttttctg ccagcgctgc ccgtaatgcc tgttcatcgc cttgatcaac
    37201 aaacaacacg cgatagcaac cgcgtttcgc cagactgtcg aacaggcgat agctaccgcc
    37261 gtagcagtcg tgcggcgcaa ccagcagatc gccaggtttc aaaaagacgg tcgttaccag
    37321 gtgaatcgcg gacatgccgg tattagtaag tactgcacca gcaccacctt ccagttctgc
    37381 cagcgcacgc tgaaccacat cgcgcgttgg gttgccgcga cgcgagtaat catgcgcgcg
    37441 cggttcatta aatccggtaa agttataggt gctggaaaga tggatcggtg ggacaacgca
    37501 accatactgt tcgtcgtcat ttaacccgct acgcactgcg atggtggcct gtttacgcgt
    37561 catgtgatga agttccctgg gctttgtcgg tgaaatgtca ggcaccagag taaacattgt
    37621 gttaatggac gtcaatacat ctggacatct aaacttcttt gcgtatagat tgagcaaatc
    37681 ccaaatagcc gttaaaatta tatgcattat cacgccgaca ggtgcattac acgatgtcac
    37741 ggtaacgcct gtacggtaaa ctatgcgggt ttacggtcag tacccacatc aactgtgtgg
    37801 tctggtctca atttattgac gaagaggatt aagtatctca tggctgaatg gagcggcgaa
    37861 tatatcagcc catacgctga gcacggcaag aagagtgaac aagtcaaaaa gattacggtt
    37921 tccattcctc ttaaggtgtt aaaaatcctc accgatgaac gcacgcgtcg tcaggtgaac
    37981 aacctgcgtc acgctaccaa cagcgagctg ctgtgcgaag cgtttctgca tgcctttacc
    38041 gggcaacctt tgccggatga tgccgatctg cgtaaagagc gcagcgacga aatcccggaa
    38101 gcggcaaaag agatcatgcg tgagatgggg attaacccgg agacgtggga atactaaagc
    38161 aaaaaagagc ggcgcggagt ggaatcgcct gatgcgctac gcttatcagg cctacgtcat
    38221 attgcaattt attgaatttg cacgaacttg taggccggat aaggcgttca cgccgcatcc
    38281 ggcataaaca acgagcacgt tgtctgcgac ccaccgcttt ttatacatgg acgtttaact
    38341 atgaaaaaca ggctgctgat cctcagcctg ctggtttctg tacctgcctt tgcctggcag
    38401 ccacaaaccg gcgacatcat ctttcagatc tctcgctcat cgcaaagtaa agcgatccaa
    38461 ctggcgaccc ataccgatta tagccacacc ggtatgctgg tgatacgcaa caaaaagccc
    38521 tacgtttttg aagcagtcgg cccggtgaaa tacaccccgc tcaagcagtg gatcgcccat
    38581 ggtgaaaagg gcaaatacgt tgttcgccgc gttgaaggcg gactgagtgt tgaacaacag
    38641 caaaaactgg cgcaaacggc aaaacgttat ctcggtaaac cgtatgattt cagcttctca
    38701 tggagcgacg atcgccagta ctgttcggaa gtggtgtgga aggtttacca gaacgcgctg
    38761 ggaatgcgcg tgggcgagca gcagaagttg aaagagttcg acctgagcag cccacaagtt
    38821 caggcaaagc tcaaagaacg ttacggcaag aatattccgc ttgaggaaac ggtggtctcg
    38881 ccacaagccg ttttcgatgc gccacaactc accacggtcg ccaaagaatg gccgctgttt
    38941 tcgtggtaat acgaccaaaa ttcaggcaca aaaaaagcgc cgtgcggcgc ttttttcgga
    39001 aatccggtct tatttgctgc ccgggatgtt gaaacgcttg ttgaagcggt caacacggcc
    39061 accggtagca acatcacgct gtttgccagt gaagaacggg tggcacttgc tgcacacgtc
    39121 gaggttcagg tcatgaccaa cggtggagcg gattttcatt acgttaccgc aagagcagct
    39181 agcagtaatt tcttcgtatt tcgggtgaat atcttttttc atgggaaaac ctcggtttaa
    39241 ggccgcgtcg ctcttccagc cctaacgcca gacaccacgc gatgttaaaa gtatagcttc
    39301 aatacgatca tttcgtacga aggcgcgaaa tcatacagaa attaaccagc gtatgcaaac
    39361 tgatccgcac tcttctacgg caatgtgtat actaacccac cgaatttcaa gtcaggatga
    39421 tgctatgccc gttgcccacg ttgccttgcc cgttccgctt cctcgtacct ttgactatct
    39481 gctgccagaa ggcatgacgg ttaaagctgg gtgtcgcgtg cgcgtgccgt ttggcaaaca
    39541 gcaggagcgc atcgggattg tggtatcagt tagcgatgcc agcgaactgc cgctcaatga
    39601 gctaaaagcg gtagtcgaag tgctggatag tgagccggtg tttactcact ccgtctggcg
    39661 attgctgcta tgggcggcag attactatca tcatccgatt ggcgatgtgc tgtttcatgc
    39721 cttgccgatt ttactacgcc aggggcggcc tgcggcgaac gcgccgatgt ggtactggtt
    39781 tgccactgaa caaggccagg cggtggatct gaacagcctg aaacgctccc ccaagcaaca
    39841 acaggcgctg gcggcgttac ggcaaggcaa aatctggcgc gaccaggtcg ccacgctcga
    39901 atttaatgat gccgcgttgc aggcgctacg caaaaaaggt ctgtgtgatt tagcaagtga
    39961 aacaccagag tttagcgact ggcgaacgaa ctatgccgtt tctggtgagc ggttgcgatt
    40021 gaataccgaa caggccaccg ccgttggcgc aattcatagc gcggcagata ctttttctgc
    40081 ctggctgctg gcgggcgtta ccggttccgg taaaacggag gtttatctca gcgtactgga
    40141 aaacgtgctc gctcagggca aacaggcgct ggtgatggtg ccggaaatcg gcctgacacc
    40201 gcaaactatc gcccgttttc gtgaacgttt taatgccccc gtggaagttc tgcattccgg
    40261 cctgaacgac agcgagcgtc tttcggcgtg gctgaaagcg aaaaatggtg aggcggcgat
    40321 tgtgatcggc acccgctccg cgctgtttac gccgtttaaa aatctcggcg tgattgtcat
    40381 tgatgaagag cacgacagct cctacaagca gcaggaaggc tggcgctatc atgcccgcga
    40441 cctggcggtg tatcgtgcgc acagcgagca aatcccgatt attcttggct ccgcaacgcc
    40501 cgcgctggaa acgttatgca acgtccagca gaaaaaatac cgcctgctgc gcctgacccg
    40561 tcgggcaggg aatgcgcgtc cggcaattca acatgtgctg gatttaaaag gtcagaaggt
    40621 gcaggcaggt ctggctccgg cgttaatcac tcgtatgcgc cagcatttac aggctgataa
    40681 ccaggtcatt ctctttctta accgccgtgg ctttgcgcct gcactgctgt gccacgactg
    40741 tggctggatt gccgaatgcc cacgttgcga tcactactac acgctgcatc aggcgcagca
    40801 ccatctgcgc tgccaccact gtgacagtca gcgtccggtg ccgcgccagt gcccttcctg
    40861 cggttccacg cacctggtcc ccgtggggct gggcaccgaa cagcttgaac agacgctcgc
    40921 gccgttgttc cccggcgtgc ccatttctcg tatcgaccgc gataccacca gccgcaaagg
    40981 ggcgctggaa cagcaactgg cagaagtaca tcgcggcggc gcgcggattt tgattggtac
    41041 acaaatgctg gcgaaaggtc accatttccc ggatgtgacg ctggttgcat tactggacgt
    41101 ggacggcgcg ctgttttctg ccgattttcg ctcggcagag cgtttcgctc agctttacac
    41161 ccaggtcgcc ggtcgtgccg ggcgtgcggg taaacagggc gaagtggtgc tgcaaacgca
    41221 ccatccggaa catcctctgt tgcaaacgtt gctctataaa ggctacgacg cctttgccga
    41281 acaggcgctg gctgagcggc gaatgatgca gctaccgccg tggaccagcc atgtgattgt
    41341 gcgtgcggaa gatcataaca atcagcacgc gccattgttc ctgcaacaac tgcgtaatct
    41401 gatcctctcc agcccactgg cagacgagaa actgtgggtt ctcggtccgg ttccggctct
    41461 ggcacctaaa cgtggcggtc gctggcgctg gcagatattg ttgcagcacc cttcccgcgt
    41521 gcgcttgcaa cacatcatta acggtacgct ggcgctcatc aatacaatac cggattcccg
    41581 taaggtgaaa tgggtgctgg atgttgatcc gattgagggt taaaccgctc acgatgcgag
    41641 gcggatcgaa aaattcaata ttcatcacac ttttcatgaa aattctgtaa ccgttttcac
    41701 gcgctatctg ctaaaaatgt tgccgatgtg aagtaaacat ggatgtagta cgcctgacgt
    41761 gccaggcgag gagtgagtgt gaaagcgaag aagcaggaaa ctgccgcgac catgaaagac
    41821 gttgccctca aggcaaaagt ctctacagcg accgtctccc gagcattaat gaatcccgat
    41881 aaagtctccc aggccacccg taatcgggtt gaaaaagcgg cccgggaagt gggttattta
    41941 ccgcagccta tggggcgcaa cgtcaagcgt aatgaatccc gcaccattct ggtgattgtc
    42001 ccggatatct gcgatccctt ctttagcgaa attattcgcg gtatcgaagt tacggcggca
    42061 aatcacggat atctggtgct gattggcgac tgtgcgcatc aaaatcagca ggaaaaaacc
    42121 tttatcgatt tgatcatcac caagcaaatt gatggcatgt tgttgctggg ttcaaggctg
    42181 ccgtttgatg ccagcattga ggaacagcgt aatctgccgc cgatggtgat ggcgaacgaa
    42241 tttgcaccgg agctggagct gcctacagtt catatcgaca atctgaccgc cgcatttgat
    42301 gcagtaaatt atttatatga gcaagggcat aaacggattg gctgtatagc cggtcccgaa
    42361 gagatgccgc tgtgtcacta ccgcctgcaa ggctatgttc aggcgctgcg tcgctgcggc
    42421 attatggttg atccgcaata catcgcccgt ggcgacttca ccttcgaagc cggaagcaaa
    42481 gcgatgcagc agctgcttga tcttccacaa ccgcctactg ctgtcttctg ccatagcgat
    42541 gtgatggcgc tcggcgcact ttctcaggca aaacgccagg ggctgaaagt cccggaagac
    42601 ctttccataa tcggttttga taacatcgac ctgacgcaat tttgtgatcc gccgctgaca
    42661 accatcgcgc agccgcgtta cgaaatcggt cgggaagcta tgctgttatt gcttgatcaa
    42721 atgcaggggc aacacgttgg cagtggctct cgtttaatgg actgcgaact tatcatccgg
    42781 ggatcaacac gcgcgttacc ttaaagtaaa cctttaagac tgccgtgact ggtcaaaggc
    42841 ccgccgctta agtaacatgg cgggctgacg aacgaataaa tacagcgaaa cgatagtggc
    42901 acaacgagat tatgtacgcc gcagccaacc ggcaccttcg cggcgaaaaa agagcacctc
    42961 acggaaaaag caacgaaatc tgcctgcggt ttctcccgct atggtcgcta ttgctgccgc
    43021 cgttcttgtg acctttatcg gtggtctgta cttcattacg catcacaaga aagaagagtc
    43081 cgagacgctg caaagccaga aagtgaccgg aaacggacta ccaccaaaac cagaagaacg
    43141 ctggcgctac attaaagagc tggaaagtcg ccagccggga gtgcgtgcgc ccacagaacc
    43201 ttctgccggt ggtgaagtga aaacgccgga gcaactgaca ccagaacaac gtcagcttct
    43261 tgaacaaatg caggctgata tgcgccagca gccaacgcag ctggttgaag ttccgtggaa
    43321 tgaacagacg ccggaacagc gtcagcaaac gctacagcgc caacgtcagg cgcagcaatt
    43381 agcggaacag caacgcctgg ctcagcagtc gcgtacgact gaacaaagct ggcagcagca
    43441 gacgcgtacg tcgcaagccg caccggtaca ggcgcaaccg cgccagtcta aaccggcttc
    43501 ttctcagcag ccgtaccagg atctgctgca aactcctgcg cacacgactg cgcagtcgaa
    43561 gccgcagcaa gctgcgccag ttgctcgtgc cgctgacgcg ccaaaaccga cggcggagaa
    43621 aaaagacgaa cgccgctgga tggtgcagtg cggttcgttc agaggcgcgg aacaggcaga
    43681 gacggtacgt gctcagctgg cgttcgaagg ctttgactcg aaaatcacca ccaacaatgg
    43741 ctggaatcgt gtggtcattg gcccggtgaa aggcaaagag aacgcagaca gcaccctcaa
    43801 tcggttgaag atggcgggtc atacaaactg cattcggctc gccgccgggg gttgaaaccc
    43861 tcaaaatccc ccccatctat aattgcatta tgccccgtac ttttgtacgg ggtttgtact
    43921 ctgtattcgt aaccaagggg tcagctcgtg acaactatag taagcgtacg ccgtaacggc
    43981 catgtggtca tcgctggtga tggtcaggcc acgttgggca ataccgtaat gaaaggcaac
    44041 gtgaaaaagg tccgccgtct gtacaacgac aaagtcatcg cgggctttgc gggcggtact
    44101 gcggatgctt ttacgctgtt cgaactgttt gaacgtaaac tggaaatgca tcagggccat
    44161 ctggtcaaag ccgccgttga gctggcaaaa gactggcgta ccgatcgcat gctgcgcaaa
    44221 cttgaagcac tgctggcagt cgcggatgaa actgcatcgc ttatcatcac cggtaacggt
    44281 gacgtggtgc agccagaaaa cgatcttatt gctatcggct ccggcggccc ttacgcccag
    44341 gctgcggcgc gcgcgctgtt agaaaacact gaacttagcg cccgtgaaat tgctgaaaag
    44401 gcgttggata ttgcaggcga catttgcatc tataccaacc atttccacac catcgaagaa
    44461 ttaagctaca aagcgtaagg atctcccatg tctgaaatga ccccacgcga aatcgtcagc
    44521 gaactggata agcacatcat cggccaggac aacgccaagc gttctgtggc gattgctctg
    44581 cgtaaccgct ggcgtcgcat gcagctcaac gaagagctgc gccatgaagt gaccccgaaa
    44641 aatatcctga tgatcggccc gaccggtgtc ggtaaaactg aaatcgcccg tcgtctggct
    44701 aagctggcga atgcgccgtt catcaaagtt gaagcgacca aattcaccga agtgggctac
    44761 gtcggtaagg aagtggattc tattattcgc gatctgaccg atgccgccgt gaaaatggta
    44821 cgcgtccagg ctatcgagaa aaaccgttat cgcgctgaag aactggcaga agaacgtatt
    44881 ctcgacgtgc tgatcccacc tgctaaaaac aactggggac agaccgaaca gcagcaggaa
    44941 ccgtccgctg ctcgtcaggc attccgcaaa aaactgcgtg aaggccagct tgatgacaaa
    45001 gaaatcgaga tcgatcttgc cgcagcaccg atgggcgttg aaattatggc tcctccgggc
    45061 atggaagaga tgaccagcca gctgcagtcc atgttccaga acctgggcgg ccagaagcaa
    45121 aaagcgcgta agctgaaaat caaagacgcc atgaagctgc tgattgaaga agaagcggcg
    45181 aaactggtga acccggaaga gctgaagcaa gacgctatcg acgctgttga gcagcacggg
    45241 atcgtgttta tcgacgaaat cgacaaaatc tgtaagcgcg gcgagtcttc cggtccggat
    45301 gtttctcgtg aaggcgttca gcgtgacctg ctgccgctgg tagaaggttg caccgtttcc
    45361 accaaacacg ggatggtcaa aactgaccac attctgttta tcgcttctgg cgcgttccag
    45421 attgcgaaac cgtctgacct gatcccggaa ctgcaaggtc gtctgccaat ccgcgttgaa
    45481 ctgcaggcgc tgaccaccag cgacttcgag cgtattctga ccgagccgaa tgcctctatc
    45541 accgtgcagt acaaagcact gatggcgact gaaggcgtaa atatcgagtt taccgactcc
    45601 ggtattaaac gcatcgcgga agcggcatgg caggtgaacg aatctaccga aaacatcggt
    45661 gctcgtcgtt tacacactgt tctggagcgt ttaatggaag agatttccta cgacgccagc
    45721 gatttaagcg gtcaaaatat cactattgac gcagattatg tgagcaaaca tctggatgcg
    45781 ttggtggcag atgaagatct gagccgtttt atcctataat cgcgttcaat cattttcatc
    45841 attgtttgat ggggctgaaa ggccccattt ttattggcgc gtattatgac tgaacaacaa
    45901 attagccgaa ctcaggcgtg gctggaaagt ttacgaccta aaaccctccc cctcgccttt
    45961 gctgcaatta tcgtcgggac agcgctggca tggtggcaag gtcacttcga tccgctggtc
    46021 gccctgctgg cactaattac cgccgggcta ttacagatcc tttctaacct cgccaatgat
    46081 tacggcgatg cggtaaaagg cagcgataaa cctgaccgca ttgggccgct acgcggcatg
    46141 caaaaagggg tcattaccca gcaagagatg aaacgggcgc tcattattac cgtcgtgctc
    46201 atctgtctct ccgggctggc actggttgca gtggcatgcc atacgctggc cgattttgtc
    46261 ggtttcctga ttcttggcgg gttgtcgatc attgccgcta tcacctacac cgtgggcaat
    46321 cgtccttatg gttatatcgg tctgggtgat atttccgtac tggttttctt tggctggttg
    46381 agtgtcatgg ggagctggta tttacaggct catacattga ttccggcact gatccttccg
    46441 gcgaccgcat gcggcctgct ggcaacggca gtactgaata ttaataacct gcgtgatatc
    46501 aatagcgacc gcgaaaatgg caaaaacacg ctggtggtgc gcttaggtga agtgaacgcg
    46561 cgtcgttatc atgcctgcct gctgatgggc tcgctggtgt gtctggcgct gtttaatctc
    46621 ttttcgctgc atagcctgtg gggctggctg ttcctgctgg cggcaccatt actggtgaag
    46681 caagcccgtt atgtgatgcg ggaaatggac ccggtggcga tgcgaccaat gctggaacgt
    46741 actgtcaagg gagcgttact gactaacctg ctgtttgttt tagggatatt cctaagccag
    46801 tgggcagcat aactgacaaa tatcaattaa caattgatga ttttgccaac agcccacata
    46861 gcgcgatata ctgaaaattc tcgcagcaac tgaatgttaa gcctatgaaa tacgatactt
    46921 ccgagctttg tgacatctat caagaagatg ttaacgtcgt ggaaccgctg ttctccaact
    46981 ttggcggacg ggcgtcgttt ggcggacaaa taatcacggt aaaatgtttc gaggacaacg
    47041 ggttgctgta cgatctgctc gaacagaatg gccgtggtcg tgttcttgtc gtcgatggcg
    47101 gtggttctgt tcgtcgcgca ctggtcgatg ctgaactggc gcgtctggca gtacaaaatg
    47161 aatgggaagg tctggtcatt tacggcgcgg tgcgtcaggt agatgacctg gaagagttgg
    47221 atatcggcat ccaggcgatg gcggcaattc cggttggtgc cgctggcgaa ggcattggcg
    47281 aaagcgatgt ccgcgtcaat tttggcggtg tcaccttctt ctccggcgac catctttatg
    47341 ccgacaatac cgggattatt ctttcagaag atccgctgga tattgaatga taagaaaggc
    47401 accgcaaggt gccttttttc tgcgttacct gttggcctac acagtaaaga aattacgcgg
    47461 aagatgaagc gtaatcagac ctcttccatg cgacccagca gggcctgcag acgttcctgc
    47521 cagccgttct gctgttcttt cagatggttg ttctcacgct ccagctcttc gcgctgatgc
    47581 tgggcatttt gaacttcctg cgacagtgag ttgttttttt ctttcagctc ttcgatttcc
    47641 atctgcaaca gagtgatggt atcaatcgcc tgctgtactt ttgcttccag tttctcaaac
    47701 acttctaatg acattgtcat acctctcctg aattgcaagg cgttgatgga taaaaatcct
    47761 cgtcccgatt accggtgacg ccttaataaa tacgagcgca ctttagttag ctccgattgt
    47821 atgaagccgc gccatcgctg tccagcggca cgccttgcag attacggttt gccacacttt
    47881 tcatccttct cctggtgaca taatccacat caatcgaaaa tgttaataaa tttgttgcgc
    47941 gaatgatcta acaaacatgc atcatgtaca atcagatgga ataaatggcg cgataacgct
    48001 cattttatga cgaggcacac acattttaag ttcgatattt ctcgtttttg ctcgttaacg
    48061 ataagtttac agcatgccta caagcatcgt ggaggtccgt gactttcacg catacaacaa
    48121 acattaactc ttcaggatcc gattatgagt caaacatcaa ccttgaaagg ccagtgcatt
    48181 gctgaattcc tcggtaccgg gttgttgatt ttcttcggtg tgggttgcgt tgcagcacta
    48241 aaagtcgctg gtgcgtcttt tggtcagtgg gaaatcagtg tcatttgggg actgggggtg
    48301 gcaatggcca tctacctgac cgcaggggtt tccggcgcgc atcttaatcc cgctgttacc
    48361 attgcattgt ggctgtttgc ctgtttcgac aagcgcaaag ttattccttt tatcgtttca
    48421 caagttgccg gcgctttctg tgctgcggct ttagtttacg ggctttacta caatttattt
    48481 ttcgacttcg agcagactca tcacattgtt cgcggcagcg ttgaaagtgt tgatctggct
    48541 ggcactttct ctacttaccc taatcctcat atcaattttg tgcaggcttt cgcagttgag
    48601 atggtgatta ccgctattct gatggggctg atcctggcgt taacggacga tggcaacggt
    48661 gtaccacgcg gccctttggc tcccttgctg attggtctac tgattgcggt cattggcgca
    48721 tctatgggcc cattgacagg ttttgccatg aacccagcgc gtgacttcgg tccgaaagtc
    48781 tttgcctggc tggcgggctg gggcaatgtc gcctttaccg gcggcagaga cattccttac
    48841 ttcctggtgc cgcttttcgg ccctatcgtt ggcgcgattg taggtgcatt tgcctaccgc
    48901 aaactgattg gtcgccattt gccttgcgat atctgtgttg tggaagaaaa ggaaaccaca
    48961 actccttcag aacaaaaagc ttcgctgtaa tatgactacg ggacaattaa acatgactga
    49021 aaaaaaatat atcgttgcgc tcgaccaggg caccaccagc tcccgcgcgg tcgtaatgga
    49081 tcacgatgcc aatatcatta gcgtgtcgca gcgcgaattt gagcaaatct acccaaaacc
    49141 aggttgggta gaacacgacc caatggaaat ctgggccacc caaagctcca cgctggtaga
    49201 agtgctggcg aaagccgata tcagttccga tcaaattgca gctatcggta ttacgaacca
    49261 gcgtgaaacc actattgtct gggaaaaaga aaccggcaag cctatctata acgccattgt
    49321 ctggcagtgc cgtcgtaccg cagaaatctg cgagcattta aaacgtgacg gtttagaaga
    49381 ttatatccgc agcaataccg gtctggtgat tgacccgtac ttttctggca ccaaagtgaa
    49441 gtggatcctc gaccatgtgg aaggctctcg cgagcgtgca cgtcgtggtg aattgctgtt
    49501 tggtacggtt gatacgtggc ttatctggaa aatgactcag ggccgtgtcc atgtgaccga
    49561 ttacaccaac gcctctcgta ccatgttgtt caacatccat accctggact gggacgacaa
    49621 aatgctggaa gtgctggata ttccgcgcga gatgctgcca gaagtgcgtc gttcttccga
    49681 agtatacggt cagactaaca ttggcggcaa aggcggcacg cgtattccaa tctccgggat
    49741 cgccggtgac cagcaggccg cgctgtttgg tcagttgtgc gtgaaagaag ggatggcgaa
    49801 gaacacctat ggcactggct gctttatgct gatgaacact ggcgagaaag cggtgaaatc
    49861 agaaaacggc ctgctgacca ccatcgcctg cggcccgact ggcgaagtga actatgcgtt
    49921 ggaaggtgcg gtgtttatgg caggcgcatc cattcagtgg ctgcgcgatg aaatgaagtt
    49981 gattaacgac gcctacgatt ccgaatattt cgccaccaaa gtgcaaaaca ccaatggtgt
    50041 gtatgtggtt ccggcattta ccgggctggg tgcgccgtac tgggacccgt atgcgcgcgg
    50101 ggcgattttc ggtctgactc gtggggtgaa cgctaaccac attatacgcg cgacgctgga
    50161 gtctattgct tatcagacgc gtgacgtgct ggaagcgatg caggccgact ctggtatccg
    50221 tctgcacgcc ctgcgcgtgg atggtggcgc agtagcaaac aatttcctga tgcagttcca
    50281 gtccgatatt ctcggcaccc gcgttgagcg cccggaagtg cgcgaagtca ccgcattggg
    50341 tgcggcctat ctcgcaggcc tggcggttgg cttctggcag aacctcgacg agctgcaaga
    50401 gaaagcggtg attgagcgcg agttccgtcc aggcatcgaa accactgagc gtaattaccg
    50461 ttacgcaggc tggaaaaaag cggttaaacg cgcgatggcg tgggaagaac acgacgaata
    50521 atgtaaatgc cgaatgaagc gtttatgccg catccggtag tcccgaaacg tgcgggggca
    50581 accccgcaca catcaataat ccctcccttc ccctgtgcta cacttcgcgc cattccttac
    50641 tgcttagagt ttgctatgag acgagaactt gccatcgaat tttcccgcgt caccgaatca
    50701 gcggcgctgg ctggctacaa atggttagga cgcggcgata aaaacaccgc ggacggcgcg
    50761 gcggtaaacg ccatgcgtat tatgctcaac caggtcaaca ttgacggcac catcgtcatt
    50821 ggtgaaggtg aaatcgacga agcaccgatg ctctacattg gtgaaaaagt cggtactggt
    50881 cgcggcgacg cggtagatat tgctgttgat ccgattgaag gcacgcgcat gacggcgatg
    50941 ggccaggcta acgcgctggc ggtgctggca gtaggcgata aaggctgctt cctcaatgcg
    51001 ccggatatgt atatggagaa gctgattgtc gggccgggag ccaaaggcac cattgatctg
    51061 aacctgccgc tggcggataa cctgcgcaat gtagcggcgg cgctcggcaa accgttgagc
    51121 gaactgacgg taacgattct ggctaaacca cgccacgatg ccgttatcgc tgaaatgcag
    51181 caactcggcg tacgcgtatt tgctattccg gacggcgacg ttgcggcctc aattctcacc
    51241 tgtatgccag acagcgaagt tgacgtgctg tacggtattg gtggcgcgcc ggaaggcgta
    51301 gtttctgcgg cggtgatccg cgcattagat ggcgacatga acggtcgtct gctggcgcgt
    51361 catgacgtca aaggcgacaa cgaagagaat cgtcgcattg gcgagcagga gctggcacgc
    51421 tgcaaagcga tgggcatcga agccggtaaa gtattgcgcc tgggcgatat ggcgcgcagc
    51481 gataacgtca tcttctctgc caccggtatt accaaaggcg atctgctgga aggcattagc
    51541 cgcaaaggca atatcgcgac taccgaaacg ctgctgatcc gcggcaagtc acgcaccatt
    51601 cgccgcattc agtccatcca ctatctggat cgcaaagacc cggaaatgca ggtgcacatc
    51661 ctctgattga tttgatcgat tgagccttcc agtccttcgg gactggaatt tttttgttcg
    51721 gagaacgaag ataaggcaag tcaatcaaaa caggagaaaa acatggctga ttgggtaaca
    51781 ggtaaagtca ctaaagtgca gaactggacc gacgccctgt ttagtctcac cgttcacgcc
    51841 cccgtgcttc cgtttaccgc cgggcaattt accaagcttg gccttgaaat cgacggcgaa
    51901 cgcgtccagc gcgcctactc ctatgtaaac tcgcccgata atcccgatct ggagttttac
    51961 ctggtcaccg tccccgatgg caaattaagc ccacgactgg cggcactgaa accaggcgat
    52021 gaagtgcagg tggttagcga agcggcagga ttctttgtgc tcgatgaagt gccgcactgc
    52081 gaaacgctat ggatgctggc aaccggtaca gcgattggcc cttatttatc gattctgcaa
    52141 ctaggtaaag atttagatcg cttcaaaaat ctggtcctgg tgcacgccgc acgttatgcc
    52201 gccgacttaa gctatttgcc actgatgcag gaactggaaa aacgctacga aggaaaactg
    52261 cgcattcaga cggtggtcag tcgggaaacg gcagcggggt cgctcaccgg acggataccg
    52321 gcattaattg aaagtgggga actggaaagc acgattggcc tgccgatgaa taaagaaacc
    52381 agccatgtga tgctgtgcgg caatccacag atggtgcgcg atacacaaca gttgctgaaa
    52441 gagacccggc agatgacgaa acatttacgt cgccgaccgg gccatatgac agcggagcat
    52501 tactggtaag cggttactta tcgataaacg gcacgatgag caaatccgca ctcatcttat
    52561 tgatcatccc gcgatatgcc ggcatcaaac ggttgataaa tgagtgatga tgaccacaga
    52621 caaggaggtc gcactgctct ttttgcataa tttccagcag tgtttccggc atttctccgc
    52681 gttcaatacg cagttttgtc ttcggccatt gaatattttt cgtcagttta tacagcttgt
    52741 tatccgactt attcttcaac aattgaagaa tatcttctgt tgcagggaag tagatacccg
    52801 gatacaactc gcttaagcca tcatcaatat gaattaacgt caggtgagcg tcattatgtc
    52861 tggcgagctc cagggcttta ttcaccagta aggcatcttc ttcattcccg gaaattgcca
    52921 cgccaatgtg tttataagcc atgtttaact ccttctaaag caactccatc aagctaacga
    52981 acgcagtgat aactcaaaaa taatcatctc ggcctggcat gagaaagtga aggccgcatc
    53041 aagctcaact tgcccctcca gatccttaat cttataggcc acgctggccc cttcatctgc
    53101 agaggatgta gcggcggcaa gctctttcag tttggtcata aaagactctg cttcttcgcg
    53161 ggtggcaaaa aagcgcgaaa acttactggt acagttgtcg ttatcaatca ccgtaccgat
    53221 atcaatcgca catcctttag tactgcattt atctacgaca tctttcatag ggcacctctg
    53281 tatattcgcc tctctgtcga ttacgactta agaataatgc gccgttaagg gaagaacaaa
    53341 caagtaatga tcttatggat taccattttt tttgatattg cttaaggtga agagttcaga
    53401 aggattttcg gtaatgctgc caacttactg atttagtgta tgatggtgat tttaaggtgc
    53461 ttgcgtggct tccatttcca tcagatgtcc ttcctgctcc gctactgaag gcgtggtgcg
    53521 taacggcaaa agcactgccg gacatcagcg ctatctctgc tctcattgcc gtaaaacatg
    53581 gcaactacag ttcacttaca ccgcctctca gcccggtacg caccagaaaa tcattgatat
    53641 ggccatgaat ggcgtcggat gtcgcgccag tgcacgcatt atgggcgttg gcctcaacac
    53701 ggttttacgt cacttaaaaa actcaggccg cagtcggtaa cctcgcgcat acaaccgggc
    53761 agtgatgtga ttgtctgcgc tgaaatggac gaacagtggg gctacgtcgg tgctaaatca
    53821 cgtcagcgct ggctgtttta cgcgtatgac aggatacgga ggacggttgt ggcgcacgtc
    53881 ttcggtgaac gcactctggc cacactggag cgtcttctga gcctgctgtc ggcctttgag
    53941 gtcgtggtat agatgacgga tggctggccg ctgtatgaat cacgcctgaa gggaaagctg
    54001 cacgttatca gcaagcgtta cactcagcgc attgagcgac ataatctgaa tctgagacaa
    54061 catctggcaa ggctgggacg gaagttactg tcgttctcaa aatcggtgga gttgcatgac
    54121 aaggtcatcg ggcattatct gaacataaaa cactatcagt aagttggagt cattacccgt
    54181 agtgtgtgga ttgcgcctag agcttcttta ttcgttcgag cgcatcgcca atattttcta
    54241 ttgggtgcca ttgattattt ttgcttgaaa tccctctcga atgaacttac ttatcacttt
    54301 attgaatgag gtaaaaacaa ctgacatccg gctcgctgat aacgctgtgc aatagtctca
    54361 ggtaacccgc tgtcactgat gatcgtttta atacatgata gtgttgctac agcatgcggc
    54421 tcaacggcat caaattttga gtgatcggcc atgagaataa cttcacgcga gcgttgaata
    54481 atccgtgttt tcaccccgac ctcaaacatg gtggcattgg tgatccccgt ctccagcgac
    54541 agcgcatcgc aggagataaa cgcacgttct acggaaaagg cattgatcat ctccagcgcc
    54601 agactctctc ctaccgaaaa ataacctggg cgaatcagtc ctccgataat gtaactttcc
    54661 acatggggaa aacagcccag ttcattggcg attttaatgt cgttgcagat gacctttacc
    54721 cgcgcatcgg ccaggcattt cgccagttcg aggcaggttg agccggagtc gagaaaaaag
    54781 cagtcgccat ctttgatcat tgttcgggca agggcagcta tttctctttt cgccacagat
    54841 tgcaatgtac gtttcacgtc gaagacgtac tctttgtcgt ctgtactgtc gtcgaagtcc
    54901 aggcaaccgt gaccgcggat catgcctgga tactggttga caatatactg gaaatcacga
    54961 cggacagtcg cttccgcata gccaaaaagc tccatggcct gctgtgtgga gaggtgacga
    55021 tgttgccaca ggtagtgcag catctgtttg atacggtcag gtctctgttg gctcatcaga
    55081 aacaatctcc tcttacaggg tggcgaattg agctaaggtc gcgcgatagt cagatgaaga
    55141 gaacagggcg cgcccaatca ccatatgttg cgccccagct gctgccagtt gctgtgcagc
    55201 tgccagcgta attccaccgt cggcccagca ctcggtctga ggaaaagccg tgcgtacttt
    55261 ttggattttc tcgcacatgg agggaataaa ccgctgtccc tgcccatcgg gctcactggt
    55321 catcaccatc actccgtcca gctcagacgc cagatatcgc caggcgtcga tcggggttgc
    55381 cggattaaat accagtccgg ctcgtgcgcc ggtatggcgg atctcagtta acgtttccga
    55441 aggatagtcc agcgtttctg catgaacgaa gatccacgcg ggtctgattt cagccagcgc
    55501 gttaaaccag cgctgtggcc gggcaagcat gaaatgaaag gacaagggat gaggcgtctg
    55561 tctggcgacg gcctgcaccg ttttcatccc aaacgtaatg ttgttaatga agctgctgtc
    55621 ctcaatatcc agatgcaggc tcccaaaatc cagattgtcc aatgccgtca gctcacgacc
    55681 atagtgcaga ggatttgcgc tggcgagaga agggtgcagg atcataagcg cctccgttaa
    55741 cctgatacca gcgcaaacag tgcatcgtct gtgctggcat ttcccactgc cgttaagcgt
    55801 tgtggcgaat caataaactg gctgatgcgc tgaatggtca aaatatgtgc gttggcatcc
    55861 gtggcgctga cgcagagaag cagccagacg gggtcgcact cctcgttacc aaaggcgacc
    55921 ggggtgcgta gcgtggtgat actgacctga ttatagtttg cgccttgctc tggtcgggcg
    55981 tgaggcaagg cgattcctgg ggctatcaga taataaggcc cccagttaag ggtattttcg
    56041 atgatcccat taacgtagca tggctgcgcg gcaccatagg ctaccagcgg gcgggtggcg
    56101 atttccacgg cctgacgcca gtcggtggct ttacgttgtg cctgtaccca tttaatatcg
    56161 ttaatcatcc gtcgttgact ccatgccgat tcgggttaat ctggtagcga tccccgtcga
    56221 tacttttgac gaaggcggca gggatcgcag aagggttatt gctctttgcc ggggataagc
    56281 gctctgctta ttcccatctt atcggcgtat atgatgcact ttctccataa actgactgac
    56341 tcgcgcctgg tcaacgaaat tggcaaaaac gccgtccttt ttaaaggtgg ttgcggtcac
    56401 acagccatcg gcgatactga gttgttcctc cacgttttcc aggcagacgc ccgtgttggc
    56461 caacacgacg gtgtcaggca ccgtttcttt gacccgtttt aacagcgcgc tgtcggtacg
    56521 cgtcccggcg gtcaggccag aaacacagag cgcatcagga tggttgttaa atactgtcga
    56581 tttagcaata gaacagatat cgcgattgcc cagatacacg gcggcctctg ggacgatatt
    56641 gaacaaggtt ttcacttcgc ctgcaccaat ccggtgttga tgacggatgg tctcaccgac
    56701 gttagtgtcc cagacgccaa agtcgctggc ataggcaccg gtaaatatct cgcggataaa
    56761 cttagcgccg gtagccatcg ccaggtcgaa tgaggcgacc ggatcccaca gaacattcac
    56821 gccaaacggg atgcggatat cgctcattaa ttgcccgatg attcgtgcca ttgccgcagt
    56881 ggtttccgga cgcaccttcg tgagataggg aagactaaac tcgttggaga acatgactgc
    56941 atccacccca ccattttgga gcgccatcag atcgtcccag gctttgtcga taacccagtt
    57001 catccccaac tgcgcatcaa aactcgggtc gccgggcaat gcacgtagat ggcacatggc
    57061 gatgaccgct ttttccgtcc caataacctc tttcagccaa ctcattgaaa gtactcctta
    57121 ttccgataat tcacgtttac gtaagaacag cacgacgctg gcgacaatac cgaccgccac
    57181 gacaacgcca ataatcccaa gcgacatcaa ttcagaaatc gaccaaccga acatattgcc
    57241 cacggacaac gctgagattt gcgcactttc accggcaaaa ctgaaaccgc ctttgagcgc
    57301 catttcagtg aagtaaggcg cgaactgggt ggcgatcagc aggacggtaa tcatcacgat
    57361 gaccccgctt atcaacgtcc tgaccaggtc tccgcggtgg ataaccgtag ccatacagat
    57421 aaagaacggt gctaccggca ggtctgcgag gggtaacact ttgttgcccg gtaaaatgct
    57481 ggccagaatt aacataatgg gtatcagtag cagaccgaca gcaatggtgg ttggatgccc
    57541 cagcgtcaca gcagtatcca gaccgatata cacttcacgt cctttgaaat atttctggaa
    57601 gaactttctt gcaccgtcgg agatgggcag caggccctca acaatcaggc ggatcatgcg
    57661 cgggaacaac accatgattg ccgcaacggt aatcatcaga ctggcgcaac ctttaaagcc
    57721 ttcaccagcc gccaggccaa aaatcagacc gagcactacg ccgataatca ccggatcgcc
    57781 gaccatgccg tagcgtttct ggatctcctg agcatcgata ttgcgtccct tcatgaaagg
    57841 gattttttca tagatagcat caagtagaac gaaaagcggt actgaactgg aaccgtagcc
    57901 ttgcggtatc gaaatacctt ccagcccgac gatgttctgt acccgttttg ccgtccagtc
    57961 ggccattttt aacgatagcg ccgcatggca gattgccccc agcacaccat aaatcaggct
    58021 accggtcata agctggacca ccgtacccgt aatggcgtag tgccagtaat tgtaaatatc
    58081 gacgttcatc gttttggtca gacgggtgac cagcatggcg acattgagaa gaaaaataac
    58141 tgggataatc atggcgccaa tggctgtcgc ataaccaacg ccggaggcag ggcctgcgcc
    58201 aacgtcaaag acatgcaggg ctaggccgaa acgctcaatc atcactttga tagggggact
    58261 gaggctgtcg atcgccatga cgatcaccag tcccataccg acaaaaccaa tcccaaccgt
    58321 tacccctgcc ttaatcgcct gcagccaggg gatgcggaag ataaggccaa tcacgatcat
    58381 gatgataggg acgaaaacgg taccgccgag agacaggatg taatcaaaca taatgcctcc
    58441 ttttattgag ttaacagagc cttgatttgt tgttttaacg cgtcgtcgtt gatccctgtg
    58501 agcagggcgg cgccattaag cgtagggatg ccgtaatcac tgttggttcg catggaggtt
    58561 acaataaggt ccataccgtt acagttaaga gggatctcat tcagacagca ttgggcggta
    58621 gtggctgaaa tgccctgttc agtcaggaac tcttgcagct tgtgtgcaat catggttgaa
    58681 gtcgacatgc cggtaccgca tgccacaagg atctttttca taatggatgt gcctcttgtg
    58741 tagtgcctga atcaggctca acggggaaat gtgctgctga catacctgcc agagcggtca
    58801 ataggcggat gcaatcagtc aaatcacgca ggctggcaac ctccgccgga gaatgggtat
    58861 agcgacaagg aatagagaga ctggcgcagg gaataccatc ctgctcaacc tggatataac
    58921 cggtttctgt tatcacgccg ggagccactt ctcgctgcac cggaatgttg tgttcaagag
    58981 ccgtctgttc caacatccgt atcaggcgag gaggcgtgat taatccggcc agcgttcccc
    59041 gaccatggta gttcaggcag gtgatcccaa cgccctgatt aatcctgacc tcggaataat
    59101 cgtgtaaatc aggggtgtca cacgatggag tgatatcaat accaatcgcc aggtcaggtt
    59161 ttacacggcg taatacggga acaatgccgc ggatattaaa ttcttcctgt accgaagcca
    59221 ccagataaac ggcgatatca agctccatag tactgatagc atccgctaca ccgagcaggg
    59281 cagtacagcc tagacgatcg tctagtgctt tactgcacac cagatcgttt gccaggagtt
    59341 gcggcgggtt atacagagtg acaggcgtac cgacctgaat gcccatccgt atagcgtcgt
    59401 ctttgtcttt ggcaccaata tcaatccaca gtttgtcgac agaaggtgac tgcgtgcgct
    59461 cgtcgccttt ggcaaagtgg taggacttaa tgccgataca ccccatgact ggccctttgt
    59521 ccccggtgag ggtgacgatg gaaccagcca tagtgacctg cgcaggaccg cctacgcgtt
    59581 caaagcgtaa aaatccagac ggctctattt tgcgcaccat aaaaccgact tcatccatat
    59641 gcgcaaaaat catcagtcgc agcgcatcgg gtttatcact accgtagcgc gcgacgacat
    59701 tcccaagcct gtctcgccag acctcttttg cctgacgcct gaattcgcac agcatgacgt
    59761 cagcgacagc gttttcgtgt cctgaaatcg cattgtgctg caaaagcgag aacagggttt
    59821 cctgcacaga aaatgacata gctatctccg tagaccgtaa aacaatcact cgttgagcgt
    59881 tttataggcg cagactggtc gaataattgt gagaacgttc acgtgaaaac gcgcaaagct
    59941 gaacaaataa aaaattatgt gagccgagtg gaataaaagc gctcaacgtt tgtgaaagtt
    60001 acgggctgga gagaccagtg attatggttg aaataatgag gatgaataaa acgcggtaac
    60061 tgttatagca ccactttgtt gcaggacgct ccctcttcat tacgtcctgc acgtggatac
    60121 cccagcatct ccatcagcgg atcttagaat gtaatggcgc gtggcaggtc gttggttccc
    60181 agcataatgt aagaaaacat cggatctcct gaatagattc agagggagta tagataatca
    60241 gctcaaatca ctctccgctt tatgagccca ggctggcatt gccgtcagat aacgttttgc
    60301 acgcttatgt gcttcctccg ggccgacttt ttgccaggaa tcaaggaagc tggctaaacc
    60361 tgataccgct tcttcccagg gtttgagatt gccgttgctg tcgctgcatt acgcacaata
    60421 ttgatcactg gcactgtgtg catctggtgc cgacatcggc attccgcaag cctgacagaa
    60481 ctgttcatgt tgtgacatat gatgctcctt atggtgacat cttgattaat aaacatactg
    60541 aatatgtatt gtgcaggtga tacatcagat caaagcaaag gtaaagcctc gatatttcca
    60601 gccagaaata ccgggaacct gttgttaccg ggcgatgagt gcgaacacgc cccagccaaa
    60661 gcattcccgc gcgtaggtca cgtagcgttt cggcgcgatg tttagttcgg ccctgacttc
    60721 ggcggcgaag tcatcgtcag gattcgcttc cagccagcgg cgcatggtca gccattttgc
    60781 ggcttcatac cggtcccagc cttcctggtc tgccagtacc atttccacca cgtcatagcc
    60841 gagatcgtcg aacgctccga caagtcctgg cagcgtcagg aaatcgcttg tcgagctgac
    60901 gccgcaggcc tgggctattt cttctgttgc tggtagctga cgccagtagg gttcgccgat
    60961 aagcatgatc ccgcccggtt tcaggctttg cgctagcagc tcctccgccc cggcaaaccc
    61021 accggcaatc catgtcgcgc cgacgcaggc cgccacgtca catttttcat ttgcgacgta
    61081 accggccgca tcgttatgaa taaaatgtac gcgttcgctg acgccgagtt cttccgcgcg
    61141 acgctttgcc tgcgcggtga agagcgaact catgtcgatg ccagtccccg taatgccatg
    61201 atccctggcc caggtgcaga gcatctcgcc cgagccgctg ccgaggtcaa gaatgcgggt
    61261 gcccggcttc atgcgcagca cgcgacccag cgtggcgtac ttctcttcgg tgaacgggtt
    61321 atggatgcgg tgttcacttt cgctgatggt aaaaatacgt gggatatcca ttatttaatt
    61381 cctgttattg ggttaagcct taaaaaggac acaacaagat tgttattcac gtcagtgctc
    61441 cggtttcatc agggtctgcg caccggatgt ggccggtcag ggtcatgggc tgagcggtga
    61501 gtgattgcat catccagcag gctttgtgct cctccgggat gggataaggt gccggatagc
    61561 ctttgtctcc ggcacagggt tcgaacccat gtcgggggta ataggtggcg tggccgagaa
    61621 caaaaaccgt ctggcagccc atcaacctca ggtgctcgat gccagtgcgt atcaaccgtc
    61681 ctcccacgcc catcccttgg tattccggta tgaccgccag gggagcgagg atgtgcatca
    61741 acggtgaatc catttctcct ttgaaggttg cccgggtaaa taaaatatgc ccgacggctt
    61801 tgccttcata ccgggctagc agcgataacg cggggcgcgc gctttcatcc tcaagtaaag
    61861 aggccactaa atcggcttct ttgctgaagc caaatgcgcg ggtttcgact tcccggatat
    61921 cactggcatc acttttatct gtgatatgaa aagtgaagtg gtgtactgtc atagaaactc
    61981 tccttagcga ttatcgagct gagcgcgaac tttattcagc tcggtggtgt tgattcgata
    62041 gggctggcca ttgacggact tgataagttt tttggttttg agttttttga agacggcgag
    62101 cgtgcagtcg gtcagcaaca gcccttcgcg gctgtagcat tcaacggaag tgacgcggcc
    62161 tgaagaatcg cggacgtgcg caatacgtct acctttagcg agaacgtgta aggtatgttg
    62221 ttcctgacgg gataaattca tactgaagaa cctatttaat catcatgtgc aaaacgtgca
    62281 aacacaccgc ggtgtccgca ttcgatttcg gcgcattgat aatcagtccg gcctgaaaag
    62341 gtcggggaac tgattatcgg atgattacat tctccagcat caaagcctcg ggttgagttg
    62401 aaaggtattt acggagcgaa tattaacacg tagttatagg agggatatgt ttcagtagaa
    62461 aaagtgtgat gtactttgga aattgaatgc caacccattt actggaaaag gcagatgaca
    62521 ctgacgaatg catgttgaag tacgcctgaa atggcctcat cggcttttcc cttcgggaga
    62581 ttattctcct tttgttaaat ccagaacata aatatgctca cccatcttcg atgcttgaaa
    62641 aattgaagcc aatcctgata agtaattttt ttgaaagggt attttccgga ttcacaccgg
    62701 ctttgatgag tgaaaaaccg ttctctttta ttcagtcaat cgtggcggta attgcttcaa
    62761 ttgcatatcc ctggcgagca taagcgggac tgatggtata gccgagccaa aacacatcgc
    62821 attgctgacg taaatagata tcaccaatca aaacctgcgt catttgttga caatggccaa
    62881 ttgaatatcg cgagcaagtg taagaactcc cagcaagacc ctgtaaataa ttctgtgtaa
    62941 ctgcccacga ttaaaggtgg ccgctcaggc ggtcaccgta ttcgataata aatgggtctg
    63001 gaaaaagtgc agcatctggc agcgtaatgc aggtagccca gttcaactct cactaccagt
    63061 atgatcccaa gttcgagcgc ggaatgtatc tgtatgagca tcgtcgctgt ttcaataaca
    63121 tcatcgacta ctgtaactca ctttgctatc acggtaagtt gcagcctaaa agagggatgg
    63181 aaaaaggacg attttccccg caatgggata tttacatatt gatggtagag gcatgaagcc
    63241 aaatggaggg agccgtcata accctcttga agctgaaaca atagcagcat ggctggtggc
    63301 acataaggat gatatagagc gccattacgg ggaaccactg tacaaagttg ttggtgttgt
    63361 gacgccattt tcggcgcagg ttaatgctat caaaatgtca ttgcgtaagc tggaaattaa
    63421 tggcaaagac gagcagggtt tactgacagt ggggactgtg cactccttgc agggggcgga
    63481 aagggcgatt gttctctttt ctcctgtcta ctcaaaacat gaagatggca ggtttcttga
    63541 tagcaacagc actatcctca atgttgctgt ctcacgcgct aaagatagtt ttctggtatt
    63601 tggcgatatg gaccttatcg agatgcagcc cgcattttcg ccgcgagggt tattggcaaa
    63661 atatctcttt tcttcagata ataatgcgtt gcaatttgag tttcagaaac gacaggattt
    63721 aatttccgca catacacaaa tttcaacgct gcatggtgtg gagcagcatg atgaattttt
    63781 gaacaagact cttgccggag ctcaaaagaa aataacgatt atttcccctt ggttatcctg
    63841 gcaaaaagtg gagcaaacgg gatttctggc atcaatggct ttggcccgtt cccggggcat
    63901 tgatattacc gtggtgacgg ataaaaactg caatatagcg catgtcgatg atgataagcg
    63961 tcaggagaaa caacatctgc tgaatgatgc tgttgaaaag ctcaataaga tgggtatcgc
    64021 tacgaaattg gttaatcgtg ttcacagcaa aattgtgatt gaggatgaag aactgctgtg
    64081 tgtcggatct tttaactggt tcagtgctac acgggaagat aagtatcaac gatacgatac
    64141 gtctttggtg taccgtggtg aaggcgtaaa aaatgaaata aaggcaatat atggtagtct
    64201 ggatcaacgt cagctttaaa tgtgatgagc cgttcatgat acaggagtag taaagggcat
    64261 attttaccaa tgttaaggcg actttccgtt ttattgcgag tcgcctttcc tgattataaa
    64321 tcttattgtt tacctaatca ttttcctttg cataatgcgc ctgggattaa tggcgggtgc
    64381 ttttaggaat gaaagaaaat gcaagcaata atataataat ggcctaattt ctttgaacat
    64441 cattaagcat atcatcatcg tctatttgcc agaatccgtc gacttataat cgccagaacg
    64501 gcatatcagg acggtgctgc gaacgctgtg gcccaaaacg ttccagtaaa ctgtgtagat
    64561 gttcgtagat ttccgagcca taatcgaaaa ggcgcggatg tctattaagg catccggcta
    64621 atctgtaagc aataacaacg gtttatgcgg tgcgcgtttt tcacccttgt gccagattat
    64681 tatattggca attgcctgct gttcgagccc gcaagtgaag agatattacc ttgatctcat
    64741 ttgttttttg ttgtctactc tgagaacgaa caaggacatc ccccatgaat aaactccccg
    64801 ctcacctttc gcgccaaaac tgcaaaattg cttctacaaa tctgtcagaa ataatccccc
    64861 gacgggctgc agtgctgaaa tgactgcttc gcagtgccgt cgtccagttc tccggtgacc
    64921 ggtacgctga accgtaatat cccgtgctta aatcgtccgg gtcttcatca ggcgcgttcg
    64981 tcagtcctct ttcaccttgt tgctggaagt cgacgaaaat aatattggct aaaacattat
    65041 tttgataatt gccataaata gcttcatacg aatgcgggaa attttctttc cagtaccagg
    65101 tggtatcgcc gcaaaaccac ggcgcgtcag taatattatt aagctgagaa tggtattgtt
    65161 ttagatccct acgaaaggct tcaaccatat gattaaagtg ttgagggtgt gacgcgtagt
    65221 cactggtcat taagtcaaat tcgccttgca tccagcatgc gccgaggaat ttgttctgcg
    65281 gattttttgc cagtgcggct cgcgttctgc tgactaaatc ctggtacagc ggagtatccg
    65341 ttccccaacg acaagcatca tggctggctc cgtgccgttc tgaatatgtc ccttcgctgc
    65401 ccgcggtaaa agccgatccg ccacggcaac acggaacgat aagaatccct gcattatcag
    65461 gaatgaaggg cagtaatttc cgtgcaatat gcagtgcctg gccaacggtg ccgtactgtg
    65521 tttgatgatt cgttgccaga ggatggtgat aaccctgcat atcctgaaca tcgtgtgggc
    65581 agtgagtcag tggaataatg tcgttaaagt gacatggcgg gcctccggga tgcgtatgcg
    65641 caaatctcgc taattgttta attctgggat gaggcgcatc ttccctgtcc ggtaatggca
    65701 gtccttcgcc atacgccatg gcattagact gaccagcaac ggtaagaaca tagtaataat
    65761 cgggcgatat tattgcgttc atataaattt cgcgtaattg aaatgacaaa ttgatagcag
    65821 ggccccttta ccggggccct gaagcgttag ttttgtactg tgactttatt atccttcaca
    65881 gtgatcaaaa ctgaatccgt caccgctttg ccgcctgcag tttcaccgcc aataatcaat
    65941 agactattat tccagggcaa tgatactccg taggcccgac cttgcgataa ttcacccgat
    66001 ttatcccatt tcccgttatg ccaaagatga atatcagtgc tatatgattt tttcaggcct
    66061 tcatgcgcat agttcttacc gttctggtaa ttttctcgtg aacctttgaa tccggcccct
    66121 ccggcaaata taagagaatc attgcttatc cccgcaaaac cgccagctac gccatctggt
    66181 gatgagacgg gagcaagctt attccatttt aaattattac cggtgaaatc aagttcaaat
    66241 acggcatccg ttcgcaatcc tggtttggct tcgccattaa taagccaggt tttatcacct
    66301 ttattcacaa ccgccgcacc agccgttccg taccagggcg attcgccagc gtaactccat
    66361 tgctgtgttg agggatcaaa agacaacaga aacttattga agaaataatc ttctgctttt
    66421 ttgtcaaaat agtgagcatt gattttatct atagcggttg aatcttttcc agcctcgttg
    66481 agatcttcaa aatagccatt gaagatattc tggttaacac caccagtaac ataagccttg
    66541 ccgttgtgta caaaagtcac atggcccgcc atgcccatcg gcgcgtgcga catcaattta
    66601 acccaactat tggttttggg gttgtatttg tgtacgtcat taaatacctg agtcaagccc
    66661 tcgctgtttt tgccaatgcc gccaaacaca tacagattgc catcaataaa tgcagaggtt
    66721 gcttgatctc ttggtccgcc agggaatgca gctaacgctg tccatttttt atctttggcc
    66781 tgtgtatcca gcttgtacca tgccgtacct gcgctaccta aaccaatgta gacagtgtcg
    66841 ttatcaattg ctccggtacc acttttaaat ggcacaggag tttccggtaa tacagacgcg
    66901 tttgcggcaa atgaagccat catgatagca agcgccgtta ttgttttatt cattgtgact
    66961 gtctcctgtc tactacagtt taaatgacac accaatgcga taactgtttt ccgataaatt
    67021 atctctgccg ttgtaaacac cctgacggtc aaggtagtca tattctatgt atggcgtaat
    67081 atcgggcgtc atatggtatt gtagaacaaa tgcattttcc gtcgcccatt tcttatggtt
    67141 tgcatagcga taatcgttct gtttgctgta tagcgtcgtt tgccatgcga aggtgaaatc
    67201 actattaata tggtaagtga catatccatc ccaacgatga acgttatcac gagacatatc
    67261 accggataag tcttgttgtc ggtaagcttt ccagtcgtaa cgatagcgaa tgccaaaatt
    67321 aagatctttt gtcgcgtccc aggacagttt tacgtagggt ccgtagcgtg tgccgttgct
    67381 gctaaaatgc gttaacattc ccgggcgcac cgtccattga tcatcaagtt taatcgcgta
    67441 attaacttca acctgaacat cattgagtgc ggcattttcc tttttattat catgaatggt
    67501 attccaggta ttactttcca tgcttgccca ccatccattt tgccatccct cactgacttt
    67561 gagtcgagtc tcataggcgt ggcttccact acgatatcca ccacgtacgt ccagtgtcgc
    67621 agcctgagaa attaatgggg acgaaaagca cagtaataat acgccagaaa gtattttagc
    67681 ctttttcata aatttcactc atttgtagga tacagaaagc aatacaaagc ccgcataaac
    67741 aattagcatt tatgttgtgt aatatttttt tgccaggctt atagtgtctt tggcaaccgg
    67801 tagctgtatt ttatattttt ttgtataagg tctcctgtga aaaatctctt ttcacattat
    67861 ttaaataaac agagatccag attaaatacc tgagtataaa atctcttctg atgtttaatt
    67921 gatttgaatg ttcgtaagct atatcactta ctcaatccat tttacccaga gtcataaaat
    67981 agaatgtctg ttgatctcat tttcatattc ctttcagact gaagtgcgtt ttcatcaccc
    68041 gatgagaaag aactgaagtg atgtttgcca tagattgcga gatgccctgt ctcattgact
    68101 atcttggtgc acctttatac ctgttatacc agatcaaaaa tcacgcaatc catacaacaa
    68161 aaccagattt gcaattcgtg tcacaaaata tgtcgatctt tttctaagag gaagatgcca
    68221 tgtgaagcca gacgaacact tgcggtggtc ttcaaaaact aaaga
//
LOCUS       DAPHKZ010000011        64349 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.011, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000011 DAPHKZ010000000
VERSION     DAPHKZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 64349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64349
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.011"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            143..1327
                     /locus_tag="RH288_000729"
     CDS             143..1327
                     /locus_tag="RH288_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter"
                     /protein_id="HDV4029821.1"
                     /translation="MQKTATTPSKILDLTAAAFLLVAFLTGIAGALQTPTLSIFLADE
                     LKARPIMVGFFFTGSAIMGILVSQFLARHSDKQGDRKLLILLCCLFGVLACTLFAWNR
                     NYFILLSTGVLLSSFASTANPQMFALAREHADRTGRETVMFSTFLRAQISLAWVIGPP
                     LAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLPSIQRNIPVVTQPVEILPSTHRKRD
                     TRLLFVVCSMMWAANNLYMINMPLFIIDELHLTDKLAGEMIGIAAGLEIPMMLIAGYY
                     MKRIGKRLLMLIAIVSGMCFYASVLMATTPAVELELQILNAIFLGILCGIGMLYFQDL
                     MPEKIGSATTLYANTSRVGWIIAGSVDGIMVEIWSYHALFWLAIGMLGIAMICLLFIK
                     DI"
     gene            1438..2361
                     /locus_tag="RH288_000730"
     CDS             1438..2361
                     /locus_tag="RH288_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV4029822.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRL
                     IFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLVGTFLLVTHGNPTSLSISPAALF
                     WGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDW
                     LGTLLILSSVILISMDSRRRARKINRPARHK"
     gene            complement(2365..3183)
                     /gene="nlpA"
                     /locus_tag="RH288_000731"
     CDS             complement(2365..3183)
                     /gene="nlpA"
                     /locus_tag="RH288_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpA"
                     /protein_id="HDV4029823.1"
                     /translation="MKLTTHHLRTGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQ
                     DVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGY
                     KLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKE
                     GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVHDS
                     VFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW"
     gene            3405..3698
                     /locus_tag="RH288_000732"
     CDS             3405..3698
                     /locus_tag="RH288_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029824.1"
                     /translation="MKPTTLLLIFTFFAMPGIVYAESPFSSLQSAKEKTTVLQDLRKI
                     CTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERNNQSNYWEALGKVECPDM"
     gene            complement(3739..4929)
                     /gene="nepI"
                     /locus_tag="RH288_000733"
     CDS             complement(3739..4929)
                     /gene="nepI"
                     /locus_tag="RH288_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HDV4029825.1"
                     /translation="MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLV
                     SFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIA
                     APLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFIL
                     KRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVK
                     MKKS"
     gene            complement(5140..5592)
                     /locus_tag="RH288_000734"
     CDS             complement(5140..5592)
                     /locus_tag="RH288_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HDV4029826.1"
                     /translation="MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVES
                     MVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNLLQWHRILQKAR
                     LAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH"
     gene            complement(5645..6979)
                     /gene="adeQ"
                     /locus_tag="RH288_000735"
                     /gene_synonym="yicO"
     CDS             complement(5645..6979)
                     /gene="adeQ"
                     /locus_tag="RH288_000735"
                     /gene_synonym="yicO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeQ"
                     /protein_id="HDV4029827.1"
                     /translation="MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMV
                     YIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGIFANLPVALAPAMGLNAFFAFV
                     VVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALM
                     GLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCC
                     GLFFGDVHFSGVYSIPPDISGVIGEVDLSGALTLELAGIIFSFMLINLFDSSGTLIGV
                     TDKAGLIDGNGKFPNMNKALYVDSVSSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTA
                     VVVGVMFLLVMFFSPLVAIVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITT
                     VMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD"
     gene            7154..8920
                     /gene="adeD"
                     /locus_tag="RH288_000736"
     CDS             7154..8920
                     /gene="adeD"
                     /locus_tag="RH288_000736"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDV4029828.1"
                     /translation="MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLIN
                     GGEISGPIVIKGRYIAGVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMMTPVT
                     FETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
                     VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGL
                     GGKELNAYITAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNS
                     PQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGL
                     LAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQP
                     VSASDFALQFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRL
                     APACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNG
                     QVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPAL
                     KLTSQGLFDGEKFAFTTLEVTE"
     gene            complement(8966..10357)
                     /gene="uhpT"
                     /locus_tag="RH288_000737"
     CDS             complement(8966..10357)
                     /gene="uhpT"
                     /locus_tag="RH288_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HDV4029829.1"
                     /translation="MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPE
                     SYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRI
                     GIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIAL
                     ALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERK
                     IRREKKIQQLTVA"
     gene            complement(10495..11814)
                     /gene="uhpC"
                     /locus_tag="RH288_000738"
     CDS             complement(10495..11814)
                     /gene="uhpC"
                     /locus_tag="RH288_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter family glucose-6-phosphate
                     receptor UhpC"
                     /protein_id="HDV4029830.1"
                     /translation="MLPFLKAPADAPLMTDKYEIDARYRYWRRHILLTIWLGYALFYF
                     TRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVG
                     EWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLAGWPLAKVLDTWHWSGFFVVISIAAGISALLLLPFLNAQTPREA"
     gene            complement(11824..13326)
                     /gene="uhpB"
                     /locus_tag="RH288_000739"
     CDS             complement(11824..13326)
                     /gene="uhpB"
                     /locus_tag="RH288_000739"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418124.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HDV4029831.1"
                     /translation="MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWH
                     YLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRL
                     RELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLA
                     ADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRG
                     IVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIE
                     DDGSGLPPGSGQQGFGLTGMRERVTALGGTLHISCLHGTRVSVSLPQRYV"
     gene            complement(13326..13916)
                     /gene="uhpA"
                     /locus_tag="RH288_000740"
     CDS             complement(13326..13916)
                     /gene="uhpA"
                     /locus_tag="RH288_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HDV4029832.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
                     ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW"
     gene            complement(13992..14282)
                     /gene="ilvN"
                     /locus_tag="RH288_000741"
     CDS             complement(13992..14282)
                     /gene="ilvN"
                     /locus_tag="RH288_000741"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HDV4029833.1"
                     /translation="MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ"
     gene            complement(14286..15974)
                     /gene="ilvB"
                     /locus_tag="RH288_000742"
     CDS             complement(14286..15974)
                     /gene="ilvB"
                     /locus_tag="RH288_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HDV4029834.1"
                     /translation="MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQS
                     GRPGPVWIDIPKDVQTAVFEIETQPAMAEKAAAPAFSEESIRDAAAMINAAKRPVLYL
                     GGGVINAPARVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPLVEAQPRAEWHQLVADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYEQGVFAATYPGKINFMQIAAGFG
                     LETCDLNNEADPQASLQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            complement(16080..16178)
                     /gene="ivbL"
                     /locus_tag="RH288_000743"
     CDS             complement(16080..16178)
                     /gene="ivbL"
                     /locus_tag="RH288_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HDV4029835.1"
                     /translation="MTTSMLNAKLLPTAPSAAVVVVRVVVVVGNAP"
     gene            16743..16832
                     /gene="tisB"
                     /locus_tag="RH288_000744"
     CDS             16743..16832
                     /gene="tisB"
                     /locus_tag="RH288_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin TisB"
                     /protein_id="HDV4029836.1"
                     /translation="MNLVDIAILILKLIVAALQLLDAVLKYLK"
     gene            17112..18296
                     /gene="emrD"
                     /locus_tag="RH288_000745"
     CDS             17112..18296
                     /gene="emrD"
                     /locus_tag="RH288_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HDV4029837.1"
                     /translation="MKRQRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGA
                     VQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVTTSSLTVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
                     WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIG
                     GLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQ
                     SVICCLLAGLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQ
                     PV"
     gene            complement(18304..18801)
                     /locus_tag="RH288_000746"
     CDS             complement(18304..18801)
                     /locus_tag="RH288_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDV4029838.1"
                     /translation="MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQRGIRSVQLI
                     PYLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDATLQKWCGSENP
                     QPRCDCQACDWHRLCPHARQETPDSVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
                     MTMLR"
     gene            complement(18798..19160)
                     /locus_tag="RH288_000747"
     CDS             complement(18798..19160)
                     /locus_tag="RH288_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HDV4029839.1"
                     /translation="MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWH
                     QAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSDFSQFHVVRDKFLISLAVLSLAI
                     LFAVTHIHQLIVFIERVA"
     gene            complement(19150..19497)
                     /locus_tag="RH288_000748"
     CDS             complement(19150..19497)
                     /locus_tag="RH288_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
                     /protein_id="HDV4029840.1"
                     /translation="MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAP
                     DFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLLIISLILMV
                     VAVIVMGLVLYAG"
     gene            19605..20054
                     /locus_tag="RH288_000749"
     CDS             19605..20054
                     /locus_tag="RH288_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029841.1"
                     /translation="MGIIAQNKISSLGMLFGAIALMMGIIHFSFGPFSAPPPTFESIV
                     ADKTAEIKRGLLAGIKGEKITTVEKKEDVDVDKILNQSGIALAIAALLCAFIGGMRKE
                     NRWGIRGALVFGGGTLAFHTLLFGIGIVCSILLIFLIFSFLTGGSLV"
     gene            complement(20101..21594)
                     /locus_tag="RH288_000750"
     CDS             complement(20101..21594)
                     /locus_tag="RH288_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HDV4029842.1"
                     /translation="MKRPNFLFVMTDTQATNMVGCYSGKPLNTQNIDSLAAEGIRFNS
                     AYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKNISTMGRYFKDAGYHTCYIGKWH
                     LDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
                     TWAHRISNRAVDFLQQPARADEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKA
                     QDDLANKPEHHRLWAQAMPSPVGDDGLYHHPLYFACNDFVDDQIGRVINALTPEQREN
                     TWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERRQVDTPVSHIDLLPT
                     MMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLV
                     LNLFTSDELYDRRNDPNEMHNLIDDIRFADVRSKMHDALLDYMDKIRDPFRSYQWSLR
                     PWRKDARPRWMGAFRPRPQDGYSPVVRDYDTGLPTQGVKVEEKKQKF"
     gene            complement(21591..23306)
                     /locus_tag="RH288_000751"
     CDS             complement(21591..23306)
                     /locus_tag="RH288_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HDV4029843.1"
                     /translation="MNSLQILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKA
                     PVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGI
                     ATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHG
                     AAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFM
                     QGIEQLTTVHAEKLNSIGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLA
                     EGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPMVGFFG
                     AVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLV
                     APWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITI
                     NYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDMKPWKNVKIAS
                     IGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPD
                     GKDSL"
     gene            23473..24366
                     /locus_tag="RH288_000752"
     CDS             23473..24366
                     /locus_tag="RH288_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418136.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDV4029844.1"
                     /translation="MNGKLQSSDVKNETPYNIPLLINENVISSGISLISLWHTYADEH
                     YRVIWPRDKKKPLIANSWVAVYTVQGCGKILLKNGEQITLHGNCIIFLKPMDIHSYHC
                     EGLVWEQYWMEFTPTSMMDIPVGQQSVIYNGEIYNQELTEVAELITSPEAIKNNLAVA
                     FLTKIIYQWICLMYADGKKDPQRRQIEKLIATLHASLQQRWSVADMAATIPCSEAWLR
                     RLFLRYTGKTPKEYYLDARLDLALSLLKQQGNSVGEVADTLNFFDSFHFSKAFKHKFG
                     YAPSAVLKNTDQHPTDASPHN"
     gene            complement(24363..25177)
                     /locus_tag="RH288_000753"
                     /pseudo
     CDS             complement(24363..25177)
                     /locus_tag="RH288_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312649.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25177..26793)
                     /locus_tag="RH288_000754"
     CDS             complement(25177..26793)
                     /locus_tag="RH288_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312650.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDV4029845.1"
                     /translation="MLSQIQRFGGAMFTPVLLFPFAGIVVGLAILLQNPMFVGESLTD
                     PNSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVMVSFLTWNYFI
                     NAMGMTWGSYFGVDFTQDAVAGSGLTMMAGIKTLDTSIIGAIIISGIVTALHNRLFDK
                     KLPVFLGIFQGTSYVVIIAFLVMIPCAWLTLLGWPKVQMGIESLQAFLRSAGALGVWV
                     YTFLERILIPTGLHHFIYGQFIFGPAAVEGGIQMYWAQHLQEFSLSAEPLKSLFPEGG
                     FALHGNSKIFGAVGISLAMYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFI
                     SPLLFAVHAVLAASMSTVMYLFGVVGNMGGGLIDQVLPQNWIPMFSNHADMMLTQIAI
                     GLCFTLLYFVVFRTLILQFNMCTPGREDAEVKLYSKAEYKASRGQTTAAEPKKELDQA
                     AGILQALGGVGNISSINNCATRLRIALHDMSQTLDDEVFKKLGAHGVFRSGDAIQVII
                     GLHVSQLREQLDSLINSHQSAENVAITEAV"
     gene            27089..27805
                     /locus_tag="RH288_000755"
     CDS             27089..27805
                     /locus_tag="RH288_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDV4029846.1"
                     /translation="MIYKSIAERLRIRLNSADFTLNSLLPGEKKLAEEFAVSRMTIRK
                     AIDLLVAWGLVVRRHGSGTYLVRKDVLHQTASLTGLVEVLKRQGKTVTSQVLIFEIMP
                     APPAIASQLRIQINEQIYFSRRVRFVEGKPLMLEDSYMPVKLFRNLSLQHLEGSKFEY
                     IEQECGILIGGNYESLTPVLADRLLARQMKVAEHTPLLRITSLSYSESGEFLNYSVMF
                     RNASEYQVEYHLRRLHPEKS"
     gene            complement(27802..29463)
                     /locus_tag="RH288_000756"
     CDS             complement(27802..29463)
                     /locus_tag="RH288_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HDV4029847.1"
                     /translation="MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVG
                     HFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     IGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSY
                     AMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIKTINIRVENPNLHD
                     LAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQ
                     EVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGD
                     ISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
                     GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKS
                     GGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPP
                     ALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG"
     gene            complement(29659..30087)
                     /gene="ibpB"
                     /locus_tag="RH288_000757"
     CDS             complement(29659..30087)
                     /gene="ibpB"
                     /locus_tag="RH288_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709512.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HDV4029848.1"
                     /translation="MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAEN
                     MEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS"
     gene            complement(30199..30612)
                     /gene="ibpA"
                     /locus_tag="RH288_000758"
     CDS             complement(30199..30612)
                     /gene="ibpA"
                     /locus_tag="RH288_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HDV4029849.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN"
     misc_feature    complement(30606..30678)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            30918..31250
                     /locus_tag="RH288_000759"
     CDS             30918..31250
                     /locus_tag="RH288_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HDV4029850.1"
                     /translation="MIRNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVI
                     PPARMPDN"
     gene            complement(31252..32466)
                     /locus_tag="RH288_000760"
     CDS             complement(31252..32466)
                     /locus_tag="RH288_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312656.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HDV4029851.1"
                     /translation="MKQITFAPRNHLLTNTNTWTPDSQWLVFDVRPSGASFTGETIER
                     VNIHTGEVEVIYRASQGAHVGVVTVHPKSEKYVFIHGPENPDETWHYDFHHRRGVIVE
                     GGKMSNLDAMDITAPYTPGVLRGGSHVHVFSPNGERVSFTYNDHVMHELDPALDLRNV
                     GVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAYEEGWVGNHALAF
                     IGDTLSPKGEKVPELFIVELPQDEAGWKAAGDAPLSGTETTLPAPPRGVVQRRLTFTH
                     HRAYPGLVNVPRHWVRCNPQGTQIAFLMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQ
                     SAFNWHPSGEWLGFVLDNRIACAHAQSGEVEYLTEHHANSPSADAVVFSPDGQWLAWM
                     EGGQLWITETDR"
     gene            32567..33631
                     /gene="cbrA"
                     /locus_tag="RH288_000761"
     CDS             32567..33631
                     /gene="cbrA"
                     /locus_tag="RH288_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418145.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M resistance protein"
                     /protein_id="HDV4029852.1"
                     /translation="MEHFDVAIIGLGPVGSALARKLAGKMQVIALDKKHQCGTEGFSK
                     PCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHA
                     FDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSM
                     VRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY
                     PMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG
                     FISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA
                     PALRKWIMRSGVAHIPQLKD"
     gene            complement(33628..34965)
                     /locus_tag="RH288_000762"
     CDS             complement(33628..34965)
                     /locus_tag="RH288_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4029853.1"
                     /translation="MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICY
                     VDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIA
                     IFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
                     TSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKA
                     ELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLT
                     WFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPII
                     CGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVF
                     NFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG"
     gene            complement(35040..36188)
                     /gene="dgoD"
                     /locus_tag="RH288_000763"
     CDS             complement(35040..36188)
                     /gene="dgoD"
                     /locus_tag="RH288_000763"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HDV4029854.1"
                     /translation="MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAA
                     VHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPV
                     WQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAV
                     DAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAE
                     YYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAE
                     AYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFS
                     MVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW"
     gene            complement(36185..36802)
                     /gene="dgoA"
                     /locus_tag="RH288_000764"
     CDS             complement(36185..36802)
                     /gene="dgoA"
                     /locus_tag="RH288_000764"
                     /EC_number="4.1.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HDV4029855.1"
                     /translation="MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQ
                     WEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGM
                     TVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPE
                     NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ"
     gene            complement(36786..37664)
                     /gene="dgoK"
                     /locus_tag="RH288_000765"
     CDS             complement(36786..37664)
                     /gene="dgoK"
                     /locus_tag="RH288_000765"
                     /EC_number="2.7.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HDV4029856.1"
                     /translation="MTARYIAIDWGSTNLRAWLYQGDHCLESRQSEAGVTRLNGKSPA
                     AVLAEVTTDWREEKTPVVMAGMVGSNVGWKVAPYLSVPACFSSIGEQLTSVGDNIWII
                     PGLCVSHDDNHNVMRGEETQLIGARALAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
                     GELHHLLLNHSLIGAGLPPQENSADAFTAGLERGLNTPAILPQLFEVRASHVLGTLPR
                     EQVSEFLSGLLIGAEVASMRDYVAHQHAITLVAGTSLTARYQQAFQAMGCDVTAVAGD
                     TAFQAGIRSIAHAVAN"
     gene            complement(37661..38350)
                     /gene="dgoR"
                     /locus_tag="RH288_000766"
     CDS             complement(37661..38350)
                     /gene="dgoR"
                     /locus_tag="RH288_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate utilization transcriptional
                     regulator DgoR"
                     /protein_id="HDV4029857.1"
                     /translation="MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNI
                     IREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVR
                     NLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
                     VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMI
                     ASSTRRLKEIT"
     gene            38628..39284
                     /locus_tag="RH288_000767"
     CDS             38628..39284
                     /locus_tag="RH288_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029858.1"
                     /translation="MKLNFKGFFKAAGLFPLALMLSGCISYALVSHTAKGSSGKYQSQ
                     SDTITGLSQAKDSNGTKGYVFVGESLDYLITDGADDIVKMLNDPALNRHNIQVADDAR
                     FVLNAGKKKFTGTISLYYYWNNEEEKALATHYGFACGVQHCTRSLENLKGTIHEKNKN
                     MDYSKVMAFYHPFKVRFYEYYSPRGIPDGVSAALLPVTVTLDIITAPLQFLVVYAVNQ
                     "
     gene            complement(39330..40142)
                     /gene="yidA"
                     /locus_tag="RH288_000768"
     CDS             complement(39330..40142)
                     /gene="yidA"
                     /locus_tag="RH288_000768"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDV4029859.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTG
                     RPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE
                     VGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAI
                     GDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN"
     gene            complement(40257..40655)
                     /locus_tag="RH288_000769"
     CDS             complement(40257..40655)
                     /locus_tag="RH288_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418153.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HDV4029860.1"
                     /translation="MGLFDEVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQSGGL
                     GAILSTWLSNQQGNQSVSGEQLESALGTNAVSDLGQKLGVDTSTASSLLAEQLPKIID
                     ALSPQGEVSPQANNDLLSAGMELLKGKLFR"
     gene            complement(40895..43309)
                     /gene="gyrB"
                     /locus_tag="RH288_000770"
     CDS             complement(40895..43309)
                     /gene="gyrB"
                     /locus_tag="RH288_000770"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDV4029861.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
                     EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQ
                     TVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFI
                     TGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYK
                     GLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            complement(43338..44411)
                     /gene="recF"
                     /locus_tag="RH288_000771"
     CDS             complement(43338..44411)
                     /gene="recF"
                     /locus_tag="RH288_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDV4029862.1"
                     /translation="MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDG
                     HKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
                     RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTF
                     SFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            complement(44411..45511)
                     /gene="dnaN"
                     /locus_tag="RH288_000772"
     CDS             complement(44411..45511)
                     /gene="dnaN"
                     /locus_tag="RH288_000772"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDV4029863.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCE
                     NVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            complement(45516..46919)
                     /gene="dnaA"
                     /locus_tag="RH288_000773"
     CDS             complement(45516..46919)
                     /gene="dnaA"
                     /locus_tag="RH288_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDV4029864.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVA
                     QTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
                     PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNA
                     IEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEIN
                     GVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVR
                     ELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVA
                     DLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREE
                     SHDIKEDFSNLIRTLSS"
     gene            47216..47296
                     /locus_tag="RH288_000774"
     CDS             47216..47296
                     /locus_tag="RH288_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029865.1"
                     /translation="MTIDKNWLNRSNKDPGRSLRFTHQPV"
     gene            47526..47666
                     /gene="rpmH"
                     /locus_tag="RH288_000775"
     CDS             47526..47666
                     /gene="rpmH"
                     /locus_tag="RH288_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDV4029866.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            47683..48042
                     /gene="rnpA"
                     /locus_tag="RH288_000776"
     CDS             47683..48042
                     /gene="rnpA"
                     /locus_tag="RH288_000776"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDV4029867.1"
                     /translation="MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            48006..48263
                     /gene="yidD"
                     /locus_tag="RH288_000777"
     CDS             48006..48263
                     /gene="yidD"
                     /locus_tag="RH288_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDV4029868.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            48266..49912
                     /gene="yidC"
                     /locus_tag="RH288_000778"
     CDS             48266..49912
                     /gene="yidC"
                     /locus_tag="RH288_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDV4029869.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAA
                     GSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLET
                     SPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
                     FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT
                     ANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            50018..51382
                     /gene="mnmE"
                     /locus_tag="RH288_000779"
     CDS             50018..51382
                     /gene="mnmE"
                     /locus_tag="RH288_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDV4029870.1"
                     /translation="MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPR
                     YADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPG
                     LRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRE
                     ASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVR
                     NKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            51625..51699
                     /gene="tnaC"
                     /locus_tag="RH288_000780"
     CDS             51625..51699
                     /gene="tnaC"
                     /locus_tag="RH288_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase leader peptide"
                     /protein_id="HDV4029871.1"
                     /translation="MNILHICVTSKWFNIDNKIVDHRP"
     gene            51920..53335
                     /gene="tnaA"
                     /locus_tag="RH288_000781"
     CDS             51920..53335
                     /gene="tnaA"
                     /locus_tag="RH288_000781"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HDV4029872.1"
                     /translation="MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSE
                     DVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQG
                     RGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
                     TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAK
                     KYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPM
                     GGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYR
                     IAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIR
                     AVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIK
                     GLTFTYEPKVLRHFTAKLKEV"
     gene            53426..54673
                     /gene="tnaB"
                     /locus_tag="RH288_000782"
     CDS             53426..54673
                     /gene="tnaB"
                     /locus_tag="RH288_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity tryptophan permease TnaB"
                     /protein_id="HDV4029873.1"
                     /translation="MTDQAEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAF
                     ILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTY
                     AYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWLSSLAASRITSLFLGLKI
                     ISFVIVFGSFFFQVDYSILRDATSSTAGTSYFPYIFMALPVCLASFGFHGNIPSLIIC
                     YGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLG
                     TKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHGGRFKTVLLTFLPP
                     ALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIV
                     ILFGITVILCWFGNVFNVLPKFG"
     gene            54805..55980
                     /gene="mdtL"
                     /locus_tag="RH288_000783"
     CDS             54805..55980
                     /gene="mdtL"
                     /locus_tag="RH288_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtL"
                     /protein_id="HDV4029874.1"
                     /translation="MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQG
                     LGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
                     WAMAMMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVI
                     LTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQV
                     LFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIA
                     QVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA"
     gene            55955..56914
                     /gene="yidZ"
                     /locus_tag="RH288_000784"
     CDS             55955..56914
                     /gene="yidZ"
                     /locus_tag="RH288_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HDV4029875.1"
                     /translation="MKKSITTLDLNLLLCLQLLMQERSVTKAAKRINVTPSAVSKSLA
                     KLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELA
                     AESPLMMIMLNALSKQIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
                     ELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHQTWNLDTFLRYPHISICWEQSDTWAL
                     DNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPL
                     PFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA"
     gene            57071..57820
                     /locus_tag="RH288_000785"
     CDS             57071..57820
                     /locus_tag="RH288_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HDV4029876.1"
                     /translation="MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRG
                     LLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLD
                     MELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLN
                     DDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWELDGKHGWK
                     SLPDIHSRANNPTSRMMRFAQLSTVKAFSPN"
     gene            57842..58408
                     /gene="yieF"
                     /locus_tag="RH288_000786"
                     /gene_synonym="chrR"
     CDS             57842..58408
                     /gene="yieF"
                     /locus_tag="RH288_000786"
                     /gene_synonym="chrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I chromate reductase YieF"
                     /protein_id="HDV4029877.1"
                     /translation="MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIA
                     DIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLP
                     DQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
                     GEVIDQGTLDHLTGQLTAFGEFIQRVKI"
     gene            complement(58462..59799)
                     /gene="adeP"
                     /locus_tag="RH288_000787"
     CDS             complement(58462..59799)
                     /gene="adeP"
                     /locus_tag="RH288_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HDV4029878.1"
                     /translation="MSHQHTTQTSGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLG
                     WMLGDVHYNGIVSAPPSVMTVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH"
     gene            59964..60629
                     /gene="yieH"
                     /locus_tag="RH288_000788"
     CDS             59964..60629
                     /gene="yieH"
                     /locus_tag="RH288_000788"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HDV4029879.1"
                     /translation="MSRIEAVFFDCDGTLVDSEVICSRAYVTMFQEFGITLDPEEVFK
                     RFKGVKLYEIIDIVSLEHGVTLAKTEAEHVYRAEVARLFDSELEAIEGAGALLSAITA
                     PMCVVSNGPNNKMQHSMGKLNMLHYFPDKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
                     NCILVDDSVAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTHLSQLPELWKARGWD
                     ITA"
     gene            60696..61163
                     /locus_tag="RH288_000789"
     CDS             60696..61163
                     /locus_tag="RH288_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CbrB"
                     /protein_id="HDV4029880.1"
                     /translation="MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLVLWVIIH
                     PIFLLLSITTGAIPALLTGVMVACLPEKIGSQKRYRCLAGGIGGVVITEIYCAVIVHI
                     KGMASSELFENILSGDSLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS"
     gene            61212..61799
                     /locus_tag="RH288_000790"
     CDS             61212..61799
                     /locus_tag="RH288_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbrC family protein"
                     /protein_id="HDV4029881.1"
                     /translation="MTQNIRPLPQFKYHPKPLETGAFEQDKTVECDCCEQQTSVYYSG
                     PFYCVDEVEHLCPWCIADGSAAEKFAGSFQDDASIEGVEFEYDEEDEFAGIKNTYPDE
                     MLKELVERTPGYHGWQQEFWLAHCGDFCVFIGYVGWNDIKDRLDEFANLEEDCENFGI
                     RNSDLAKCLQKGGHCQGYLFRCLHCGKLRLWGDFS"
     gene            complement(61861..62583)
                     /locus_tag="RH288_000791"
     CDS             complement(61861..62583)
                     /locus_tag="RH288_000791"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDV4029882.1"
                     /translation="MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMY
                     EYLTTLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLT
                     IDNYREHDQKLAREGGLDLVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
                     HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASV
                     LQLHPSLMVIADKAAAAELALG"
     gene            complement(62598..63767)
                     /locus_tag="RH288_000792"
     CDS             complement(62598..63767)
                     /locus_tag="RH288_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418175.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDV4029883.1"
                     /translation="MNIKIAALTLAIASGISAQWAIAADMPASPAPTIPVKQYVTQVN
                     ADNSVTFRYFAPGAKNVSVVVGVPVPDNIHPMTKDEAGVWSWRTPILKGNLYEYFFNV
                     DGVRSIDTGTAMTKPQRQVNSSMILVPGSYLDTRSVAHGDLIAITYHSNALQSERQMY
                     VWTPPGYTGMGEPLPVLYFYHGFGDTGRSAIDQGRIPQIMDNLLAEGKIKPMLVVIPD
                     TETDAKGIIPEDFVPQERRKVFYPLNAKAADRELMNDIIPLISKRFNVRKDADGRALA
                     GLSQGGYQALVSGMNHLESFGWLATFSGVTTTTVPDEGVAARLNDPAAINQQLRNFTV
                     VVGDKDVVTGKDIAGLKTELEQKKINFDYQEYPGLNHEMDVWRPAYAAFVQKLFK"
     gene            complement(63794..>64349)
                     /gene="bglH"
                     /locus_tag="RH288_000793"
     CDS             complement(63794..>64349)
                     /gene="bglH"
                     /locus_tag="RH288_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="carbohydrate-specific porin BglH"
                     /protein_id="HDV4029884.1"
                     /translation="GFNEFSFLVANNSIASNFGRYAGASPFTTFNGRYYGDHTGGTAV
                     RLTSQGEAYIGDHFIVANAIVYSFGNDIYSYETDAHSDFESIRAVVRPAYIWDQYNQT
                     GVELGYFTQQNKDANSNKFNESGYKTTLFHTFKVNTSMLTSRPEIRFYATYIKALENE
                     LDGFTFEDNKDDQFAVGALAEIWW"
BASE COUNT        15832 a        16981 c        16160 g        15376 t
ORIGIN      
        1 tctcaattgc tggccctata atattgcgct agcattgctt tctggttgta tcagcgatac
       61 tcaaaaattc ttaatacaat actcattcga ctggtactta tttgtaactc agttatattt
      121 tttcgcccgg tgattcagaa gaatgcaaaa aacggctacc actccatcaa aaatacttga
      181 tctcactgcc gcggcatttt tacttgtcgc ctttctgacg ggtattgcgg gcgctcttca
      241 gactcctacc ctaagtatat tcctcgcaga tgaactgaaa gcccgtccta taatggtagg
      301 ttttttcttc accggtagcg ctattatggg aattctggtc agtcaatttc tggcaaggca
      361 ctccgataaa caaggcgacc gtaaattact gattctgcta tgttgcttat ttggagtgct
      421 ggcctgcacg ctttttgcgt ggaatcgcaa ctacttcatt ctcctctcaa cgggcgtact
      481 tctgagtagt tttgcttcca ccgcaaaccc gcaaatgttc gccctcgccc gtgaacacgc
      541 cgacagaaca ggccgtgaga cggtcatgtt cagtacattt ttacgtgctc agatctcgct
      601 tgcctgggtt atcgggccac cgctcgctta tgaactggca atgggattta gttttaaagt
      661 gatgtatctc accgctgcca tcgcatttgt tgtttgcgga ctgatagtct ggttgttttt
      721 gccatcaata caaagaaata ttcctgtcgt tacccaaccc gtagaaattt taccctccac
      781 ccacaggaag cgggatacgc ggctactttt tgtggtctgt tcaatgatgt gggcggcgaa
      841 taatctctac atgataaata tgccgctatt tattattgat gaactgcatc taaccgataa
      901 actggctgga gaaatgattg gtatcgctgc cggtctggaa attccgatga tgttaatcgc
      961 aggctattac atgaaacgta ttggcaagcg actattaatg ctcattgcta tcgtgagtgg
     1021 aatgtgtttt tacgccagcg tactcatggc gacgactccg gcggttgagc tggaattgca
     1081 aattcttaat gccatcttcc ttggtattct ctgtggtatc ggcatgcttt attttcagga
     1141 cttgatgcct gaaaaaatag gctctgcgac aacgttatat gcaaatactt cacgcgtcgg
     1201 ctggattatc gccggctctg ttgacggaat tatggttgaa atctggagct accatgcgtt
     1261 gttctggctg gcgataggga tgttgggtat tgcgatgatt tgcctgctgt ttattaaaga
     1321 tatttagctc accagtctgg gctaagaaaa atcggcgtgg cgcaaacaga gccatcctcg
     1381 ccatttttgc tatcatgcct gcatacataa acgacaaaac agtatgcaga gggaaaaatg
     1441 ggttccacca gaaaggggat gctgaacgtt ctgattgccg ccgtgttgtg gggaagttca
     1501 ggggtctgcg cgcaatacat catggagcaa agccagatgt cgtcgcagtt tttgactatg
     1561 acgcgtttga tattcgccgg tttgattcta ctgacgctgt catttgttca tggcgataaa
     1621 atcttttcta ttattaacaa tcataaagat gccattagcc tgctgatttt ttccgtggtt
     1681 ggcgcgctaa ctgtacagct cacttttttg ctaaccatcg aaaaatcgaa cgcagccacg
     1741 gcaacggtgc tgcaattcct ctcaccgacg attatcgtcg cctggttctc actggtgcgt
     1801 aaatcgcgcc cgggcattct ggttttctgc gctattttga catcgctggt cgggactttt
     1861 ttattggtga cacacggtaa tccgacgtca ttatcgatct ctcctgccgc gttgttctgg
     1921 ggcattgcct cggcatttgc tgctgcattc tataccacct atccctcaac gctaattgcc
     1981 cgctatggca cgttaccagt cgtcggctgg agtatgctga ttggcggtct gattctgttg
     2041 cctttttatg ccagacaagg aacaaacttt gtcgttaacg gcagtttgat tctggcgttt
     2101 ttttatttgg tggtcattgg tacgtccctg acatttagtc tgtacctgaa aggagcacaa
     2161 ttaattggcg gtccaaaagc cagcattttg agctgtgcag aaccattaag tagcgcgcta
     2221 ctctctttgc tgttgctggg gatcacgttc acattaccgg actggctggg aacgctgctg
     2281 attctgtcat cggtgatttt gatttcaatg gattcccgtc gccgcgccag aaaaataaat
     2341 cgtccggcgc ggcataagtg agaattacca gccaggcacc gcgccaccgt taaaaatggt
     2401 ttctgccgct ttagcgactt cgggtgattg ataagattgc agaaattcct tcacgttttc
     2461 tgcattctta ttatcttccc gtgccaccaa aatattcaca tacggcgaat tcttatcttc
     2521 aataaatacg ctgtcgtgca ccggagaaag cccggtctgc tgaatgtaag tggtgctgat
     2581 aatcgctaca tcaactttgg gatcatccag tacgcgcggg agctgcgccc cctcgagttc
     2641 cataatctgc aaatgacgag gattatcggt tatatccagc gcggtaggta ataacccttt
     2701 tccctctttc agagtaatta gcttctcttt ttgcaacagt aaaagtgcgc gaccaaggtt
     2761 ggtcgggtcg ttggggatcg ccactgtcgc gccttctttt atttgcgcca cggttttgat
     2821 ttttttggaa taacccgcca tagggaagac aaacgtattt cccaccgcta ccagtttata
     2881 accatgcgcc tgattatctt gttcaagaaa gggtcgatgc tggaagacat tcgcatcaag
     2941 ttcgccatga tttgtcgcat cgttcggtag caacgaaccg ctaaatccta ccagttcaac
     3001 atcgaggcca tatttctctt ttgccacctt tttagcgact tccgcgacat cttgttctgc
     3061 gccatttata acgccaactt taatgtgttt tgcatcgctg ctactctggt cgcaacctgc
     3121 cagcagaatt ccggccagca ataatgcggc ccctgtccgt agatgatgtg ttgtcagttt
     3181 cattttttta tccttttatt aatgattacc tgactatagc ggtaaggtcg ctgcggttta
     3241 aaaaacgaaa cgctatcgat aagaataaaa aggaataaaa gtggaatata aagtctggca
     3301 cttcttactg accacgcaag cgcgtttcgt acagcatgat gagagcgatg aaagcaaact
     3361 acacttatgc ttcattcgat acacatttgt aaaaggttga atccatgaaa ccaacgacac
     3421 tactgcttat tttcactttt ttcgctatgc caggcatcgt atacgccgag tcgcctttta
     3481 gctcactgca gtccgcaaaa gagaaaacca cggtattaca agatttacgt aaaatttgca
     3541 cgccacaggc gtcattatca gatgaagcgt gggaaaagtt aatgttgtca gatgaaaaca
     3601 ataaacaaca tatacgcgag gccatcgtgg cgatggaacg taataatcag agcaattatt
     3661 gggaagcgtt gggtaaggta gaatgcccgg atatgtaaga acagcaacaa ctactgacca
     3721 acgcttcttt acctgatatc aggatttctt cattttcacc tttgcagtaa ccaacaatgc
     3781 agtcagcaac atcaatgtgc cggacaacat caacggcgaa gtcagaccaa tattatccag
     3841 cgcataaccg ccgattgccg cgccacaggt attagcaagc tgaataaccg ccacctgaat
     3901 agacccggct ttttctgcct gatcggccag cgagcgggtg atccacgttg accagccgac
     3961 gggaaccaat gcaaaagtta gcccccagat aatcgccacg ccggtagcaa cgattttatc
     4021 gcttccccac aacgtcagta ccaacgcact cacagccagt attaacggcg cgcctgctaa
     4081 ggccagtttt accgaacgtt taagaatgaa cgacgaaagc gacgtaccaa taaagctggc
     4141 gataccaaaa ctcaacagca ccagcgttaa gccatccacg ccgaatcccg ccaggttcat
     4201 atacaccggg cgaatatacg taaagaaagc aaactgcccg gcgaaagaca tgaagatggc
     4261 gatcatccct gccatcacac ccggacgttg taataagcgg aaagtatttt gtttctgatg
     4321 cgagggttcg cctggcagtg aaggcaatga tttgataatc cagaaaatac acagcacgcc
     4381 catcaccgcc gccgcattaa agacattgcg ccaaccgata agctcgccta aaaaactgcc
     4441 caacggcgcg gcaatcacca gcgcaataga aaccgcgccg aagatcaccg acagcgcctt
     4501 cggcaccgta cgcggcggca ccagacgcat ggtcagcgac gccgacatcg cccagaaccc
     4561 gcccagcgcc agccccagac aggcacgacc gattaaaagc aaactgaatg agttagcaaa
     4621 ggaaaccagc aagcaggaga gcgtcagcaa aacggcaaac aaaataacaa cgtagcggcg
     4681 gtcagtagcc tgaattgtct gggtaataaa caaactggca aacattgcca caaaggcggt
     4741 cacggtcacc gattgcccgg caaccccttc cgaaatgcct aaatcctggg ccattggcgt
     4801 caacaaactg acgggcaaaa actcaacgat aatcagacag gcgacacaaa acgccaccga
     4861 gaaaacggct gaccagttcg gtcgggtgat ggcatccgcg ccgcggtttt cggcaataaa
     4921 ttcactcatg gtgttacccg tggcatgttt caggggaaaa gccgaccact ttaacattga
     4981 aatgtgtgac gcatttaacg tttttgcaac ttttacggtg ttgcttgagc tggagttaag
     5041 atcgaaacgg aacagggcaa agattaccgg atgcggcgtg aacgtcttat ccacccgaca
     5101 ggtcaggcgc ggtctgtagg ctgataagac gaaacggttt caatgcaacc agtgaacgcc
     5161 ctcggcaggc tgaaagaacg cgttatagcg catctgaaaa gcattaatat cctgcatttc
     5221 aggttcggtt tcgcgcagaa aacctagcgc cagcctgacc tgagcgtcgg taatcggcgc
     5281 ggcgaggcga gctttttgta aaatccgatg ccattgcagc aggttctgtt cgctaccatc
     5341 gacaatgaca atttgccaga tgagcaacac ctgcgcggcg ttttgcaggt gcgactcatc
     5401 cggacgatgc aaataacgta aaaattcgtc accagctgac tttcccattt gatcgaccat
     5461 cgactccacg ggtacgacat cgatgttcag ccgatcgctg agacggcgaa tcgcttttct
     5521 ggccccggat gtcagcaccc gaaaaccaac cacaaacact accgccagcg tggcgagcat
     5581 tatccagatc atgagttctc ctgcgtaatc agaactcatg atatctggaa accctcgcca
     5641 gttactaatc caccagaata atcttcagtg caaacagagc tgcgaccacc accacacaca
     5701 ggttcagatc gcgccagcgc ccggtgcata ctttcatgat gcagtacgac ataaagccga
     5761 gtgcaatccc ttcggtgatc gagaaagtaa agggcatcat caccgtggta ataaacgcag
     5821 gcaccgattc ggtaaaatca tcccagttaa cgcgcgccag gctcgaagtc atcagcacgc
     5881 caacaaagat taacgctccg gcggttgcgt aaggaggaac tatcgccacc agcggtgaga
     5941 agaacataac caacaggaac ataacgccaa ccacaaccgc agtcagcccc gtgcggccac
     6001 cgactgccac accagaagta ctttcaatat aggcagtaac agacgaggtg ccgataaacg
     6061 cacccgccac cgaactgacg ctatcaacat acagcgcctt attcatattg gggaatttac
     6121 cgttaccatc tattaagccc gctttatcag ttacaccaat taatgttcct gatgaatcaa
     6181 ataggttgat cagcataaag gagaaaatga taccggcgag ttcaagtgtt aacgcgccgc
     6241 tcaaatctac ttcaccaatg acgccgctaa tatcaggcgg aatggaatag acgccgctaa
     6301 aatgaacatc accgaaaaat aatccacagc aagacgtcac cacaatagaa accagcaccg
     6361 cggcatgaaa atgacgtgat gacaacacgg ttataataaa aaaccctaaa atacctaaca
     6421 acacgccgtg agaacttaaa tcgccaatca tcaccagcgt gtctttattg gcgacaataa
     6481 cgccagtatt ttttaatccc attaaggcga taaataatcc aattccgctg gtgataccaa
     6541 tacgtaaact taagggaatg ttggagatca tccagtaccg gatacgaaac agcgtgagca
     6601 aaaatagtcc aactgcgccc cagaatattg cgcccatccc ggtctgccag gagatgccca
     6661 tcgcccccac gaccacgaag gcaaagaagg cgttcagccc cattgccgga gccagcgcca
     6721 cgggtaagtt agcaaatatc cccatcgcaa tactgccgat accggcaatc aaacaggtgg
     6781 taacaaacac cactttcggg tccatttgtg ccgcgccgag gatttgcggg ttcacaaaaa
     6841 cgatgtacac catggttaaa aaagtggtca tccccgcaat caattctgtg cggacggtgg
     6901 tcccatgctg aggtagttta aataatcgcg aaagcgtccc tgattcatta ctcacgtaat
     6961 cggtattgtc attattcatt tttttgtcca ttggaggaga tttaatccct tgcttttgta
     7021 aaacaaatga caacaacggt tcagtgataa ttatcacatt tcaattgcac attaatggat
     7081 attctttaat aatctcgcga cgtttcttta tgataaataa taatcaaatt gataaaatca
     7141 aaatgagaaa aatatgaata attctattaa ccataaattt catcacatta gccgggctga
     7201 ataccaggaa ttgttagccg tttcccgtgg cgacgctgtt gccgattata ttattgataa
     7261 tgtctctatt ctcgacctga tcaatggcgg agaaatttcc ggcccaattg tgattaaagg
     7321 acgttacatt gccggtgttg gcgcagaata cactgatgct ccggctttgc agcggattga
     7381 tgctcgcggc gcaacggcgg tgccagggtt tattgatgct cacctgcata ttgaatccag
     7441 catgatgacg ccggtcactt ttgaaaccgc taccctgccg cgcggcctga cgaccgttat
     7501 ttgcgaccct catgaaatcg tcaacgtgat gggcgaagcc ggattcgcct ggtttgcccg
     7561 ctgtgccgaa caggcaaggc aaaaccagta cttacaggtc agctcttgcg tacccgccct
     7621 ggaaggctgc gatgttaacg gtgccagttt tacccttgaa cagatgctcg cctggcggga
     7681 ccatccgcag gttaccggcc ttgcagaaat gatggactac cctggcgtaa ttagcgggca
     7741 gaatgcgctg ctcgataaac tggatgcatt tcgccacctg acgctggacg gtcactgccc
     7801 gggtttgggt ggtaaagaac ttaacgccta tattactgcg ggtattgaaa actgccacga
     7861 aagttatcag ctggaagaag gacgccggaa attacaactc ggcatgtcgt tgatgatccg
     7921 cgaagggtcc gctgcccgca atctcaacgc gctggcaccg ttgatcaacg aatttaacag
     7981 cccgcaatgc atgctctgta ccgatgaccg taacccgtgg gagatcgccc atgaaggaca
     8041 catcgatgcc ttaattcgcc gcctgatcga acaacacaat gtgccgctgc atgtggcata
     8101 tcgcgtcgcc agctggtcga cggcgcgcca ctttggtctg aatcacctcg gcttactggc
     8161 acccggcaag caggccgata tcgtcctgtt gagcgatgcg cgtaaggtca cggtgcagca
     8221 ggtactggtg aaaggcgagc cgattgatgc gcaaacctta caggcggaag agtcggcgag
     8281 actggcacaa tccgctccgc catatggcaa caccattgcc cgccagccag tttccgccag
     8341 cgactttgcc ctgcaattta cgcccggaaa acgctatcgg gtcattgacg tcatccataa
     8401 cgaattgatt acgcactccc actccagcgt ctacagcgaa aatggttttg atcgcgatga
     8461 tgtgagcttt attgccgtac ttgagcgtta cgggcaacgg ctggctccgg cttgtggttt
     8521 gcttggcggc tttggactga atgaaggtgc gctggctgcg acggtcagcc atgacagcca
     8581 taatattgtg gtgatcggtc gcagtgccga agagatggcg ctggcggtca atcaggtgat
     8641 tcaggatggc ggcgggctgt gcgtggtacg taacggccag gtacaaagtc atctgccgtt
     8701 acccattgcc gggctgatga gcaccgacac ggcgcagtcg ctggcggaac aaattgacgc
     8761 cttgaaagcc gccgcccgtg aatgcggtcc gttacccgat gagccgttta ttcagatggc
     8821 gtttctttct ctgccagtga tccccgcgct aaaactaacc agtcaggggc tatttgatgg
     8881 cgagaagttt gccttcacta cgctggaagt cacggaataa taaaaaaagc ccggcgtcat
     8941 gccgggcaaa agtcaccagt tacgtttatg ccactgtcaa ctgctgaatt tttttctcgc
     9001 ggcggatttt gcgttcttcc attaccgcca ctatcgccat caggcagata caaccaatcg
     9061 cggcgatatc cagcgcggcg aaggtgcctg cccagccggt aaggccgaat accggcgtcc
     9121 catcggcaat cattcccaga cctaacttgg caaagctgtc accaatcagg taagcaaagg
     9181 tgcctttaat accatcggca gcgccaatcg cttttttagg tacaaagcca acagcagcca
     9241 caccaatcaa caattgcggg ccaaagacca ggaaacccaa cgcaaagaga gaagccagat
     9301 agatatattc gttactggca tgttgataca caccgagcgt ggcgataatc agcgccagcg
     9361 cgatgcaggc caccaggcca cggcgaccgt tcgccaggtc agagagccag ccccacagca
     9421 gcgtaccgac cagcgcacca gcttcaaaca gcgtaaagcc ctgaatcgcc accgctttag
     9481 agagtttcag ttcctggaac gcgtatacgg ttgaccactg gtcgatacca atacgtacca
     9541 catagaggaa aatgttggcg aagcacagca gccagatcac tttgtttttc agcacatact
     9601 caacaaagat ctgccacttg gtcatatcgg tagattctgt ctctttgtcc tcttcgctga
     9661 tctcctcgcc gaacagttct tcagctttgc cgaggccata agattccggg gagtcgctgc
     9721 cgtaacgcag gccgataaaa ccgacaatca gcgcgataat cgacgggaag ataaacatgc
     9781 cgatgacatg gccatcgaac aggtaatttg ccccgaacag cgccacacct gctgcgcctg
     9841 caccgccaag gttgtgagaa atattccaga aaccgaggaa tgtcccgcgt ttacgacgcg
     9901 gcgtccattt ggtgatggtg gagtaactgc acgaaccgcc ggtactctgg aaaaagccgc
     9961 ttaaggcgta gaaggcaatc atcaggaaca ggctaaccga gccgctgccc atactggcac
    10021 tgaagcccag catacaaata gcagagagga tcagcatgaa cggcaggaat tgtttggtgt
    10081 ttttgccgtc ggcgtagtag gaaaccagcg ttttacccac gccataagtg atggagaaac
    10141 ccaggccgat catccccagc tgcgtcatgc tcaacccgta ggtcgaaatc atatcgttct
    10201 gcgcgatgtt aaagttcttg cgaatcaggt acatcgtcag gtagccgata aagaccacca
    10261 ggtaggattg catgaacggt ttgaaccaca ttttgcgccg cacttcgagc ggaaggtcca
    10321 gggtcggctt gcgaacctgg tttaagaaag ccagcatggg ttactcctga aatgaatacc
    10381 tgcgtgaggc atgcattgta aaaatcagca gcaaatcagg cctgagatag cgtccaggca
    10441 aaacctggaa aatttcttag ttttgccgga tatgaagtga aaaggtgaga tgcatcacgc
    10501 ttcgcgcggt gtctgggcgt tcaaaaaggg cagtaacagc agtgcggaaa tcccggcggc
    10561 gatagagata accacaaaaa atccgctcca gtgccaggta tcgagtactt tcgccagcgg
    10621 ccaaccagca agcgacgccc ccagataagc aaacaagccg acaaaccccg tcgccgcccc
    10681 tgccgcctct ttgtgggaac actctgccgc cgccataccg attaacatct gtgggccaaa
    10741 gacaaaaaaa ccaatggtga agaagcaggt tgcctgcatc acgtagctgg caaatggcat
    10801 cagccacagg gagccgactg aaagcaaaat tccggcggcg aaaatcaaat tcatcggccc
    10861 tcggttgccg ttaaacaatt tgtccgagcc ccaaccggct accagcgcac cgataaatcc
    10921 gcccagttca aacatcgtca ctgccgtatt cgccgtgacc agatcgacgc ccagtgtctc
    10981 ggacatatac aaattgcccc agtcgttgat cgccgcccgg accacataga ccagcacata
    11041 gcaaaacgaa agcagccaga tatacggatt cagcaacaca tatttggtga ggatctcttt
    11101 acgcgtcaac cctgcccctt cttgttgttg agcaatttcc agcgcgtcgt gtcgccattc
    11161 accgaccgcc ggtaaaccta acgcctgcgg gcgatcgcgt agccgccagc agagaaaaat
    11221 ccccacgact atcgccatac aaccagcaat catcatcccg gcacgccagc cgtaatgcag
    11281 cgcagccgct gccatcacaa tgggaatgag tgcgccgccg acgttatgcg ccgtgttcca
    11341 taatgcccac caaccgccgc gctcggtacg tgaataccag gccgttaaca gacgcgcaca
    11401 caccggtgaa ccccagccct ggaaaaaggc gttcagcacc cagagcacgg caaacgccca
    11461 tagcgacgtc gagaagccaa acagaatgtt gataatgccc gtggcgataa gccctatccc
    11521 cataaaataa cgggcatttg agcgatcgct gacaatgccg gagacaaact tcgacacgcc
    11581 ataggtaatg taaaacaggg tcgctaacag gccgatatcg ctacggctga gcacgccgtt
    11641 agcaaggatt tctggtacgg cggcgttaaa acttttccgc gtgaagtaaa acagcgcgta
    11701 acccagccag atggtcagca gaatatgccg acgccagtag cgatagcggg catcaatttc
    11761 atatttatca gtcattaatg gcgcatcggc aggcgctttc agaaacggca acatcatcaa
    11821 accttagaca tagcgttgag gtagagaaac gctgacacgc gtgccgtgca gacaggaaat
    11881 gtgtaatgtg ccacccagcg ccgttacgcg ctcgcgcatt ccggtgaggc caaaaccttg
    11941 ttgcccggaa cccggcggca aaccgctgcc atcgtcttca ataaccagca tcaaccgttc
    12001 atcctgctgc cagccttgca gggtgaccgc gctggcatca gcatgtttca caatgttgtt
    12061 cagcccttcc tggcagacac gaaacagcgt cacgcgctgg ttttcgctta acgctgattc
    12121 atcgattcgc cattcgagat ggctgacaat accgcgccct tccagctcca tttcccgcat
    12181 cagtgagcgg atggcctgct ccagggtgag atcatccaac tggcgcggac gtaaccgacc
    12241 caacaaacgg cgcaccgcgt cgtaaacgcc cagcgatagt tgttcgatga gctgcccgct
    12301 ctgcttcacg ctggcgttat ctgccgccag ccgctgaaca atgcccgcct gagtacgaat
    12361 agcagtgatg gtctgaccga tatcatcatg cagctcacgc gccacatcac ggcgcacgct
    12421 ctcttcggtt tccagcaacc gttcagccag atgctgattg cgcgccagtt ccttttgcag
    12481 cgactggtta agttcacgca accgctggat gccagcgcca agcaacaacc ctgtcagact
    12541 ttgcaccagc agcgagagca ataaatccac cggatgatcg cgccaggttt gactggcgat
    12601 cagcgcgatg gcgttcatca acgtcgcaat cagcgcccct tgccaaccat agtgccaggc
    12661 cagcgcgata atcggcagcg ccagacagaa tggcgtaaag cgcgacagtt cgtccggcaa
    12721 tcccaactgg agccagagac tgataacaaa cagcagcaag taccagacca gatgtcgccc
    12781 gcgccagttg attggctgag aaaccagtga cggaccgagc ggcagccagg tgttattggc
    12841 gagatagtgc cagaacacca gacatatcgg ggccagcgtc aggccgccag ttaaagtcag
    12901 caacagcgca ttccacgact ctttgccgtg ccaaagccag ggcagcgact gcaacaacgc
    12961 cgccgccgtt aacgccgccc cctgtaacag caaggtgcgc cagtcacgct gatggcgata
    13021 gcgcgagatc agcgctacgg gcagtaacgt cagtaaacta ccgatcatca ataacggaaa
    13081 atgggttaaa ccgaccgcct gcgttagcca gtaaatcagc agccactccg cgcccagcaa
    13141 tacgggccag tatccgcgcg ggcattgcag cattagcccc agacgcagac caaacggaaa
    13201 taacagcacc gccatatcag ggcgctcaac cagatgcagg ctgatactcc acaggcaaaa
    13261 ccatgcggca gagaagataa aaaagcaggc aataacggta attaagcggg agaacaacgt
    13321 cttcatcacc agccatcaaa catgcggcgc gccagctcta cgtcgttact gacgcccagt
    13381 ttttccatca gattggcgcg atggacgtgt accgttttcg gtgacaagcc cagttcggcg
    13441 gcaatctctt tcaccgccat tccttgcgcc agtttttccg ccacctggcg ttcacgtttg
    13501 gttagcgggt cctgacgacc ggatgccagt ttaatggcaa tatccggcgt cagataacag
    13561 ccgcccgtgg caaccgtatg caccgcagca atgagttcat ccgggctaca gcgtttggaa
    13621 agaaagccgc gtgcccccgc gttaagcgcc tgctcaacca gcgcaggact gtcgtgaacg
    13681 gagagcataa tcgtcgccat acctttcggc agctggctta gcagctccag accggagata
    13741 tcgggcatgg agatatcgca aatacacacc tgcacaccgc gccccggcag ccccgccagc
    13801 gcctcgcgcc ccgaaccaaa ctcggcaact acctgcaaat caggttccag ccccagcagc
    13861 tgcgcaaagc cggagcggac gatgaggtga tcgtctataa gggcaacggt gatcatggtc
    13921 ttgtcctggc gggtaaaaaa aatacgcgct taccttaacg ataagcgcga tgttgttcaa
    13981 gccttgagcg gttactgaaa aaacaccgcg atcttgttaa acatcgtcgg atcggactga
    14041 ttacgctgca ctttcacgac atcttccagc ttatcgattt ggcttatcat ctgctccaga
    14101 cgctggtcgt cattgaccag tagccagata tggcttttgt cgctgtcctg aatcggcaga
    14161 caaagaatgc cttcaacgtt aaaagcgcgg cgggcaaaaa ggccacaaac gtgggtcatt
    14221 acgcccggat ggttgcgaac ggtgagctcc agaattacgt tgtcatgagt tgtgttttgc
    14281 atggcttatt cccccaccat ttcagtattc gccgcacctg gcggcaccat cgggtaaact
    14341 ttttcttcgg catcaatgcg cacatggatc agcgccgggc cagggcgatt gatgatttcc
    14401 tgcaatgaag cctgcggatc ggcttcgtta ttcaaatcac aggtttcgag gccgaatccg
    14461 gcggcaatct gcataaagtt gattttgccc ggataggtgg cggcaaaaac gccttgctcg
    14521 tagaacagac tctgttgctg atgcaccagc cccagcgctt cgttgttcat cagaatgatt
    14581 ttgacatcca gctgattttc actggcggtc gccatctcct gaatattcat catcaggctg
    14641 ccgtcgccgg agaaacacaa cactttgcga tccgggttcg ccagcgcagc gccaatcgcc
    14701 gcaggcaggc caaaacccat cgtgcccagc ccaccggagg tcagccactg gcgtgggcga
    14761 ttgagcggat aagcttgcgc ggtccacatc tgatgctgac caacgtcggt ggtgataatt
    14821 gcattgtcat cgacacaggc ggcaacggcg ttgatcaggc cgtaatggct taacggatcg
    14881 cacgctttcg ggattggaca cggaaactca cgctgcaaat ccgctaccaa ctggtgccac
    14941 tctgcacgcg gttgcgcttc caccagcggg atcaactgcg ccagcacgtc atcaacatcc
    15001 gcctgaatcg ccacgtgcgg ctgcttgatt ttacccagct ctgcacggtc gatatcgaca
    15061 tgaatgattt tggcattcgg acagaactgc tcggttttgc caatcgcccg gtcatcaaaa
    15121 cgcgcaccga gcactatcaa caaatccgcc tcctgcaaaa tatagttggt gctgcgcacg
    15181 ccgtgcatcc ccagcatacc cagcgacaac ggatgcgctt ttggcaacat gcccagcgcc
    15241 attaaagtca tggtggtagg cagttgcgct ttctccgcca gttcacgcac ccgtgcgggc
    15301 gcattgatca caccgccgcc cagataaagc accgggcgtt tggcagcgtt aatcatcgcc
    15361 gctgcgtcac gaatgctttc ttcgctaaag gcgggggcgg cggctttttc tgccatagcg
    15421 ggctgtgttt caatctcaaa aactgccgtt tgcacatcct taggaatgtc tatccacacc
    15481 gggcctgggc ggcctgattg cgcaatgcgg aaggcatcgc tcatgacctg cgggagttct
    15541 tcgatatgtc tgaccagata gttgtgtttg gtgatgggga tagagatgcc gtaggtgtcc
    15601 acttcctgga aggcgtcggt gccgatcatc gaggcgggaa cctgaccagt gatgcaaatc
    15661 agcgggatgg agtccagccg cgcatcggca atggcggtca ccaggttagt cgcacccggt
    15721 ccgctacagg ccatacagac cgccggttta ccgtcggtgc gcgccattcc ctgagcgata
    15781 aagcccgcgc cctgttcatg acgggccaga atatggcgga tttgcgtgct ttggcttaag
    15841 gcatcgtaaa caggcaggat agaaccgccc ggaatgcctg tcacaatctt aatgccctgc
    15901 tgttccagga aatgaacgat aaattctgcg ccggtaaagc gcttacgcgt cgatgttgtg
    15961 cccgaacttg ccatgctcca gtccttttct tctgggccga ctttccggga ggtgcttaaa
    16021 cgaaaaaccc cgcccggttt gcgccggcgg ggttttggaa tcgtgtgttg ttccagtccc
    16081 tacggcgcat tgccgacgac caccaccaca cgcacgacga ccactgcggc ggatggcgca
    16141 gttggtagta gttttgcgtt gagcatggaa gtagtcattg gggaccttgt tggttttgtg
    16201 tttaacaata tttatacaag cacagcttta caggggagac aatggaaaat ttttcagcaa
    16261 gggaaaattg aggggttgat cacgttttgt actgaattgc agataacaaa aaaccccgcc
    16321 ggagcgaggt ttcgtcagtc gcctgcggct ggtaaccgca aagcacactg tattatgtca
    16381 acactgaaag tatacgtgtt ccgcgcagaa cgcgcaattt cggcacgaat tttgacgtat
    16441 ttagtgcata gttgagtatc gatcacagtt tgcgttttgt ccaaatatta ctgtttattt
    16501 atacagtaaa cttctataat atcactgtac gcaatgtgtt atgcgggggc cgcatcgtta
    16561 cccggcgcac taagtcctgg ctgaaacggg tggtgccgtc agcgccttaa ccccgcgtga
    16621 gcacactgtg ttatgtcaac aagcacaacg tttctccttg agataccgcg tgcacaacag
    16681 ctggcaacag gcagcggaaa ggtacgtcag ctggcagtgc tcctgaacca caggagacgc
    16741 gtatgaacct ggtggatatc gccattctta tcctcaaact cattgttgca gcactgcaac
    16801 tgcttgatgc tgttctgaaa tacctgaagt aattcagatt caagtcgcac caaaggggag
    16861 cgggaaaccg ctcccctttt atatttagcg tgcgggttgg tgtcggatgc gatgctgacg
    16921 catcttatcc gccctaccat ctctcccggc aacatttatt gccgcttttg tttacatatt
    16981 ctgccgctaa acaattcccc attcctggcg tatatctggc taacattcat caatgtgata
    17041 gattcctctc ccgcatttat gggaatgcgt agtgacttat tctaattatt tttataaaag
    17101 catccgtgat aatgaaaagg caaagaaacg tcaatttgtt attgatgttg gtattactcg
    17161 tggccgtcgg tcagatggcg caaaccattt atattccagc tattgccgat atggcgcgcg
    17221 atctcaacgt ccgtgaaggg gcggtgcaga gcgtaatggg cgcttatctg ctgacttacg
    17281 gtgtctcaca gctgttttat ggcccgattt ccgaccgcgt gggccgccga ccggtgatcc
    17341 tcgtcggaat gtccattttt atgctggcaa cgctggtcgc ggtcacgacc tccagtttga
    17401 cggtgttgat tgccgccagc gcgatgcagg ggatgggcac cggcgttggc ggcgtaatgg
    17461 cgcgtacttt accgcgagat ttatatgaac ggacacagtt gcgccatgct aacagcctgt
    17521 taaacatggg gattctcgtc agtccgttgc tcgcaccgct aatcggcggt ctgctggata
    17581 cgatgtggaa ctggcgcgcc tgttatctct ttttgttggt tctttgtgct ggtgtgacct
    17641 tcagtatggc ccgctggatg ccggaaacgc gtccggtcga tgcaccgcgc acgcgcctgc
    17701 ttaccagtta taaaacgctt ttcggtaaca gcggttttaa ctgttatttg ctgatgctga
    17761 ttggcggtct ggccgggatt gccgcctttg aagcctgctc cggcgtgctg atgggcgcgg
    17821 tgttagggct gagcagtatg acggtcagta ttttgtttat tctgccgatt ccggcagcgt
    17881 tttttggcgc atggtttgcc ggacgtccca ataaacgctt ctccacgtta atgtggcagt
    17941 cggttatctg ctgcctgctg gctggcttgc tgatgtggat ccccgactgg tttggcgtga
    18001 tgaatgtctg gacgctgctc gttcccgccg cgctgttctt tttcggtgcc gggatgctgt
    18061 ttccgctggc gaccagcggc gcgatggagc cgttcccctt cctggcgggc acggctggcg
    18121 cgctggtcgg cggtctgcaa aacattggtt ccggcgtgct ggcgtcgctc tctgcgatgt
    18181 tgccgcaaac cggtcagggc agcctggggt tgttgatgac cttaatggga ttgttgatcg
    18241 tgctgtgctg gctgccgctg gcgacgcgga tgtcgcatca ggggcagccc gtttaagcgc
    18301 acgtcaccgc agcatcgtca tcagctccat gggagaacga tgctgcttta tcagatcacg
    18361 catcacccgc atatgcggtg cggagtaaga ataaaacgcc tgatagcccg cacaaagcac
    18421 gctgtctggc gtctcctgcc gagcgtgcgg gcacaggcga tgccagtcgc acgcctggca
    18481 gtcacagcgc ggttgcgggt tttcgctgcc acaccatttt tgtaaggtgg cgtcaaaaag
    18541 ctcaatcgag atacgactga tatctgcccg cacccaacac tcgaacaggg caattaaaaa
    18601 tttcccccac agctctgctg tcaccgaagc ggccgtcaga tcgccccggt catcaaattc
    18661 aagataggga atgagctgta cggagcggat gccccgctgt ttgaaattgt gataaaaatc
    18721 ggcaggttgc agagcatcct tgtactctac aaccagttta tgcctgtcct cttcagcatc
    18781 aatgacctga cttcctgtca tgcgactctc tcaataaata cgataagttg atgtatatgc
    18841 gttacagcaa acagtattgc gagagataac accgcgaggg agatcaaaaa tttgtcacgg
    18901 actacgtgaa attgggaaaa atcgctattc gtgacatcca ttaaattgcg attacgggtg
    18961 tagtgccaga ggatcagcgc cacgatggcg agaatgccaa tcgaaatcca gaataacatg
    19021 cccgcctggt gccagttgtg tttgatagcc aacgccatca acgcgccgta gcccagcatg
    19081 gtacgaaacc acgccagtga tgtgcgctcc ggctgcagtc ctgggtcggc aatgcgtctg
    19141 gctttgcggc tatccggcat acaacaccag tcccataacg atcaccgcca cgaccatcaa
    19201 tattaagcta atgattaata agctgttggt gtagggcagg tcctctttca gacgcatcgc
    19261 tttttcattg cgtaaccagc gcaagtagcc atacatcgct aacccgccgg aaaacagaca
    19321 caacaacaac gccagcagtt cgcgaatgac gggcgtggcg aaatctggcg caagttgatc
    19381 aagcccaacc cccgccgcca gaaatcctag tgcagtacgg atccacgcca gaaaagtacg
    19441 ctcattagcc agcgagaagc ggtaatcagg cgcttctccg aggcgggaaa ttttcattgt
    19501 tgctcctttg caatttcact aacgctctac ctttagcggt ttttttaaga atttcgtccg
    19561 cccgtttcct gatatgcttt tgccatccgc tacaaggagg tcagatgggt atcatagctc
    19621 aaaataaaat cagttcattg ggcatgctgt tcggtgccat cgctttaatg atggggatta
    19681 tccacttttc attcggccct ttctccgcac caccgccaac gtttgaaagc atcgtggcgg
    19741 acaaaacggc tgaaattaaa agaggtcttc tcgccggaat aaaaggcgaa aaaattacca
    19801 ccgtggagaa aaaagaggac gtagatgtcg ataaaatcct caatcaaagc ggtatcgcac
    19861 tggccattgc tgcgctactt tgcgcattta ttggcggtat gcgtaaggaa aatcgctggg
    19921 gcattcgcgg cgcgctggtt tttggcggcg ggacgctggc tttccatacc ttgctttttg
    19981 gtatcggcat cgtgtgcagc attttgctga tattccttat cttttccttc ctgaccggcg
    20041 gttcactggt ttaagcagcc tgaataatgc ccgccgggtg atcatcagcg ggcattatcg
    20101 tcagaacttc tgttttttct cctccacctt caccccttgt gtcggtaggc cggtgtcata
    20161 gtcgcgtaca actggcgaat agccatcttg tggacgtgga cgaaacgccc ccatccagcg
    20221 cggccgtgca tctttacgcc acggacgcag actccattgg taactgcgga acggatcgcg
    20281 aattttgtcc atgtaatcca ataaggcgtc atgcattttg ctgcgaacgt ctgcaaaacg
    20341 gatatcatcg atcaggttat gcatttcatt tgggtcatta cggcgatcgt aaagttcatc
    20401 actggtgaag aggttgagta ccagtttaaa gtcatccgtc acccagcaac gcaccggaat
    20461 aaaaccgcca aagctgtcat gctcaatctc gtagcggtta aattccacca tcacgccgcg
    20521 tggctctttc acggcaagga tattttcccc cggcagaatc tctggttttt caatatctgc
    20581 cagcgccatc attgtcggca gtaaatcgat atgactgact ggcgtatcga cctgtcgccg
    20641 ctccccttgc ggcgaacgga tgatcagcgg aatgcgggtg atgtcgtcat acatcgccgc
    20701 ccctttactg atcagcttat gtgcgcccat catttcgccg tgatcggagg tataaataac
    20761 ccacgtattt tcacgttgct ctggcgttaa ggcattgatg acccgtccga tttggtcatc
    20821 aacaaagtca ttacaggcaa aatagagcgg atggtgataa agcccgtcat caccgactgg
    20881 cgatggcatc gcctgcgccc ataagcggtg atgttccggt ttgttagcca ggtcatcctg
    20941 tgctttctcg cccagctcgt agtaaaaatc agcgtatttc tctaaatact ccaccggaca
    21001 ggtgaacggg tgatgcggct catcatacga aaccaccatc aggaaaggct cgtctgcgcg
    21061 cgcaggctgt tgcagaaaat ccaccgcccg attgctgata cgatgcgccc aggtgaaggt
    21121 ttcgtcgata tggttcgcct gtaaatcttc gacgctgttt aggccattgc gccacaggct
    21181 aatctctttt tccgtcagtt cgctaagata gttcgcccca tcgaaccagt aatcagcgtc
    21241 ccactccggc ggacactcgc cagtgccgaa atagtcatga ccgtcgagat gccatttgcc
    21301 gatgtaacag gtgtgatagc cggcatcctt aaagtagcgc cccatagtgg agatgttttt
    21361 gcctggcgcg acgttgttgg tccacgggcc ggactggtta gcgtagatac cggtaaatag
    21421 tccggcccgt gcaggcgtac aaaccggtga acaggtgtag gcggaattaa agcgaatacc
    21481 ttccgccgcc agactatcaa tattttgcgt attcagcggt ttaccgctat agcaaccgac
    21541 catattggtg gcctgggtat cggtcatgac gaacagaaaa ttggggcgtt tcataggcta
    21601 tccttcccgt cgggagtaaa ggttacggct gggtcgtgac gatgccgcca gctgtcaaaa
    21661 atcaggtaga caatcactac ggcggcaatg aaataactga tcatcgctaa ccagcgcgta
    21721 ccgtagccgc cgaattcagc cagcccggca tagacgccaa tcatcgcgaa caggatgcca
    21781 attgacgcga tcttgacgtt tttccacggt ttcatgtcca ccgcaaacgc atctttgaag
    21841 gtgaacggcg tggcgcgcgg tttgataaaa ccgatcacca gcatcacgac cacgttgatg
    21901 cagaacgtac aggccagcac atagaggaaa tggaagtcga acttcaccag atagttgatg
    21961 gtgatgtagc tgattatgcc aatccccatc gctacttttg ccgccagcgc cgggatgcgc
    22021 gggaagaaaa agcccataat gatgatggta accagcggca cgttgtaaat gccgttgagc
    22081 tgtttcatcc agctatacag cccctgcggc gcgttggcga tccacggcgc gaccagcacc
    22141 gaaacgatag cgataaagaa accaaatttg cgcccgacgg tgaccagctg ctgcggctcg
    22201 gcattctggt taatgatgcg acggtaaata cccatactga ataacgtact ggcgctattc
    22261 agaaagccgt tgaaggtact gatcaccgca ccaaataaca ccgcgccgaa gaaacccacc
    22321 attggcactg gcagaacgtt attgaccagc gtcgggtagg ccatgtcggc tttcggtaaa
    22381 tcctgataca gatgaaacgc aatcaaccct ggcagcacca gtaccagcgg gtcgagcatt
    22441 ttcagcaccg ccgttaacag cgcccccttt tgcccttccg ccaggctttt tgacgccagc
    22501 gtgcgttgca cgatgccctg atttgtacac cagtaaaagg tgttcaccag aatcaaaccg
    22561 gtaaatgccg cgccaatcgg caagggatcg gtcgggccac cgattgagtt taatttctcg
    22621 gcgtgaacgg tggtgagttg ctcaatgccc tgcataaagc tgcccttgcc catcgcgatc
    22681 aggccaaata ccggcaccat caacccgccg ataaccagcc caataccgtt gatggagtcc
    22741 gccactgcca ttgcgcgcag tccgccgatc accgcataca aaattcccgc cagaccaagc
    22801 aaaattacca gtagccagat agccgcaccg tgagaaatct gtagcgattc cccgacgtga
    22861 aacaggctgt tgagcgccaa cgcgccggag tagagaacaa tcggcagaaa gcagacgccg
    22921 gtggcaatta ggaagcagaa gtcgatgata atacgcgtcg ttttatcata acgttcctcc
    22981 agaaaatcgg ggatggtggc aatgccgcgc ttcagatagc gcggtaaaaa gattagcgcg
    23041 aggaagatca gcgtcaccgc tgaagtcact tcccagccca tcaccgacat gccgcttttg
    23101 taggcctgcc cggaaaggcc gaccagttgt tccgtggaaa ggttggttag cattaacgaa
    23161 gcggcaataa ccggcgcttt tagtgaacgt ccggcaagaa aatagccttg ttgcgatccg
    23221 gtatctgttt tgcggacctt ccaccaggtg atcaccgcca ccagcagcgt aaaaccgaca
    23281 aaactcaaga tttgtaacga attcatctca tagcccttat ttatgtttat gtcccggacg
    23341 catgaatata gggagaggta aaatgcgtcg ggtcaggcag tcagattctt aaaatacaaa
    23401 cgtcgtatcc ctgaacggat tgttttctgt taagttcagg ttgtgagcat aattcgccgg
    23461 agggatatta aaatgaatgg aaaattgcaa agttcagatg taaaaaacga aactccgtac
    23521 aatattccct tattgattaa cgaaaatgtg atctccagcg gaatttctct gatctcgctc
    23581 tggcatacct acgccgacga gcattaccgg gtgatctggc cgcgggacaa gaagaaaccg
    23641 cttatcgcca actcatgggt tgcggtgtat accgtacaag gatgtgggaa aattctttta
    23701 aagaatggcg aacaaataac actgcatggc aactgtatta tattcttaaa gccaatggat
    23761 attcactctt atcactgtga aggtttagtc tgggaacagt actggatgga atttaccccc
    23821 accagtatga tggatattcc cgttggtcag caaagcgtta tttataatgg cgaaatttat
    23881 aatcaggaac tcaccgaagt tgctgagtta ataacttcac cagaagcaat aaaaaataat
    23941 ctggcagtcg cttttctgac gaaaattatt tatcagtgga tttgtcttat gtacgcagat
    24001 ggtaaaaaag atccacaacg gcggcaaatt gaaaaattaa ttgccacttt acatgccagt
    24061 ctgcaacaac gctggagcgt agctgatatg gctgccacga tcccctgtag cgaagcctgg
    24121 ttgcgtcgtc tgtttttacg ctataccggc aagacgccga aagaatatta cctcgatgcg
    24181 cgtctggatc tggcgctatc gctattaaag caacaaggaa actcggttgg cgaagtcgct
    24241 gatacgctca acttcttcga ctcctttcat ttcagcaaag cctttaaaca taaatttggt
    24301 tatgcgccgt cagccgtgct aaagaatacg gaccagcacc caacggatgc cagtccacac
    24361 aattaacgta actctggcca gtacgctttg ttggcctcca gcaactcatc cagaatagct
    24421 ttggcgaccg aggcgctcgg taccgttttc gacaacgtaa tcgcctgcca caggtgctga
    24481 tatgaacgct gttcccaggc gtccacgacc agtttttcca ccgccacttg ctgactcatt
    24541 aaccctttct gaaactgcgg gatatcgccg accaccagtg gttcaggccg tagtagcgca
    24601 cgcgcatctg tttgcgatct tgcagcccaa caatttgcgc catccggctt tcaataccga
    24661 ttggcatgtc acagatgttg aggattttcg cattcgggcg cagacgacgc gtggcttctg
    24721 cgacaatggc tgccgggttg gagtagttga gcatccaggc atttggtgaa tatttttcca
    24781 tataatccac cagttccagg acgccgccaa tggaacgcat gccgtacgct attccgccgg
    24841 gtccgcaagt ttcctgacca acaacgccgt ggcgcagcgg gattttttca tccagttcgc
    24901 gcatcgggta tttgccgacg cggatgtgcg ccatgacaaa atcaacgtcg ctgaatgcca
    24961 cttcaggatc ggtggtgtaa ctaaacgcaa tgtccggcgc tttttcttta aggatgactt
    25021 tacaggcttc ggcaatcact tcctgccgcg caccatcgtt atcataaaat ttcagtgcac
    25081 gaagcgggaa acggtcctga ttcgccagga gcatcaacac gatgcctggc gtaaaggtgc
    25141 ttccaccgcc tgcgacaacc actgagaatt tggtcattat actgcctccg taatggcaac
    25201 attttctgct gattgatgag aattaattaa gctatcgagc tgttcacgca gctgagatac
    25261 atgcagacca atgatcacct gaatggcatc gccactacgg aagacgccgt gcgctcccag
    25321 ctttttaaag acttcgtcat ccagcgtttg tgacatgtca tgcagtgcaa tacgtaaacg
    25381 cgtcgcgcaa ttgttaatgc tggagatatt gccgaccccg cccagggctt gcaggatacc
    25441 ggcagcctga tccagctctt tttttggctc tgccgcggtg gtttggcctc gcgaggcttt
    25501 gtattcggct tttgagtaga gtttcacttc cgcatcttca cgtcccggcg tgcacatgtt
    25561 gaactgcaga atcagtgtgc ggaaaaccac gaagtacagc agggtaaagc acaacccaat
    25621 ggcgatttgg gtcagcatca tatccgcgtg gttgctgaac atcgggatcc agttttgcgg
    25681 taaaacctgg tcaatcagac ctccgcccat gttgcccacc acaccaaaga gatacattac
    25741 ggtcgacatt gaggccgcca gcacggcgtg taccgcaaac agcaacggtg aaatgaacag
    25801 gaaggtaaat tccagcggtt cggtaattcc caccagcatg gcggttaagg ttgcgggaat
    25861 cagcaagccc gccactttta cccgattttc cggtgcggca gtgaagtaca tcgctaaaga
    25921 aatgcccacg gcaccaaaga tttttgagtt accgtgcagg gcaaaaccgc cttccgggaa
    25981 caacgatttc agcggctcgg cgctcaaact gaactcttgc agatgctgcg cccagtacat
    26041 ctgaatgccg ccttcaacag ctgccggacc aaagataaac tgtccgtaga tgaagtggtg
    26101 taaaccggtt gggatcagaa tacgttcgag gaaggtgtaa acccagaccc caagtgcacc
    26161 cgccgaacgc aggaacgctt gcagagattc aatccccatt tgtacttttg gccagccgag
    26221 caacgtcagc caggcacagg ggatcatcac caggaaggcg ataatcacca cataagacgt
    26281 cccctggaaa atgccgagaa aaaccggcag ttttttatcg aacagacggt tatgcagcgc
    26341 cgtcacaatg ccggaaatga taattgcgcc gataatgctg gtatcgaggg ttttaatccc
    26401 ggccatcatt gtcagaccgc tacctgccac cgcgtcctga gtgaaatcga cgccgaagta
    26461 gcttccccag gtcattccca tcgcgttgat gaaatagttc caggtcagga aactcaccat
    26521 caccgccaga caagcacgcc cctgcgcttg cttagcaagg ccaatgggta aaccgacagc
    26581 aaaaatcagc ggcatattac ggaataccgt ccaaccgccc tcttcaataa tgtgtacgat
    26641 ttgcgcgaat aaactgttcg gatcggtcag tgattccccg acaaacatcg ggttttgcag
    26701 caagatggca agacccacca caatcccggc gaagggaaac agcagcactg gcgtgaacat
    26761 cgcgccgcca aagcgttgaa tttgactgag catttccaca tcctcttttc tcaattctgt
    26821 aagtaggaag cctgattggt tatgcggcag gcctggagcg aggataggaa gatgcgatcg
    26881 gcagaacatg acgacccaat gggattcgtg atcgctttca tgcttttcgt tgggcggtag
    26941 agatctacgt tttcgcgaaa aagtagacct ctgtgagcac aggtacacag catcgaacac
    27001 atctttaaaa aaaagatgtt ttttcaatcg attaagcaga acttgtgtgc gcattacccg
    27061 ggcttgcagg caaaaaagag atctagagat gatctacaaa agcattgcgg agcggttaag
    27121 aattcgactt aactccgcag atttcacgct aaacagcctt cttcccggtg aaaaaaagct
    27181 ggcggaagag tttgcggtat cgcggatgac catccgtaaa gccattgacc tgctggtagc
    27241 gtgggggctg gtggtccgcc gccacggtag tggcacttac ctggtgcgca aagatgtact
    27301 gcatcaaacc gccagtctga ccgggctggt ggaggtgtta aaacggcagg gaaaaacggt
    27361 caccagccag gtgctgattt ttgaaatcat gcctgcgcct ccggccattg ccagccagtt
    27421 acggattcaa atcaacgagc agatctactt ctcccgtcgc gttcgttttg tggaagggaa
    27481 accgctgatg ctggaagaca gctatatgcc ggtaaaactg ttccgtaatc tttcgctgca
    27541 acatctggaa gggtcgaagt ttgaatatat tgaacaagag tgcgggattt tgattggcgg
    27601 taattatgaa agcctgacgc cagtgctcgc cgatagactg ctggcgcggc aaatgaaggt
    27661 agcggaacac acgccactgc tgcggatcac ctcgttgtca tatagcgaga gcggggagtt
    27721 tttgaattat tcagtgatgt tcagaaatgc cagcgaatac caggtggagt accatttacg
    27781 gcgactccac ccggaaaaga gttaaccgat actccagaag agcaccgcca gtaattgggg
    27841 ggtgataatg cgcaggaaca ttaccaacgg atagacagtg gcgtaagaga gcgccgccgc
    27901 accgctggtt ggatgaagat tattagcaaa cgccagcgcc ggaggatcgg tcatggaacc
    27961 tgccagcatc ccgcacatgg tcaggtaatt cattttggct aacatccgcg ccagaatgcc
    28021 aacagtaatc agcggaacgg cggtgatcag ggcaccataa ccaatccagc ttagcccttc
    28081 gccattgacc agggtattca caaaatcccc accagatttc agaccaacga ccgagaggaa
    28141 cagcacgatc cccagctccc gcagcgcgag gttggcgctt ggcggcataa accagtacag
    28201 cttgccgata ctgccgatac gcccgaggat caacgccata atcagcggtc cgcccgccag
    28261 ccccagtttc aacgcggccg ggaatcctgg cacaaagacg ggaatagaac ctaacaatac
    28321 gcctagcccg atgccaataa acactggcag catctgaacc tgttgcagtt tttgctgcgc
    28381 attccccagc acattggcaa cggcatcaat tgcggacgga cgccccacca gattgaggat
    28441 atcgccgaac tgcaggctga tatcgccact ggcgaccagt tcgaccccgg cacggttcag
    28501 gcgcgagata acaacgtcat agcgttcttt aaagtgcagg tcgcgaatac gttttccgag
    28561 cacgttttca ttggtgacca ccacacgctc gacgcgcaaa tcagtgcctt tcgtggacag
    28621 cgaagtatcg acctcctgac caatcaccag ttgcgcatta tgtaaatccg ctggctgacc
    28681 caccagatgc agcaaatcgc ccagttggat aatggtatct ggcgaaggaa cttttagggt
    28741 ttcttcgcgt ttcagacgcg agcagataat tttgtcgccg ttgagaatcg gtacatcttt
    28801 aatggctaaa tcatgcaggt tagggttctc aacgcgaata ttgatagtct tgatcagcgc
    28861 gccgccattg gtgcgtgaag actcgtgctg ctgagcttct gtctcgacat tgacgcggaa
    28921 aataacccgc aacatccaca tggtgaacaa aatcccgcaa atgccgaatg gatacgccat
    28981 cgcgtaactc atccccatct gatcgaccat ttccattggt gtacccaggt cgcgcaaaat
    29041 ctgctgccct gcccccagcg ctggcgtatt ggtaaccgca ccggagaaaa tccccagcac
    29101 taccggcagt ggaatatcaa acagtttatg caggatggcg gtaaccagac caccgatgat
    29161 gacgatcaga acagcaaaca ggttgaggcg taatccggag acgcgcaatg aggcaaagaa
    29221 gcccggccct acctgaatcc cgatagtata aacgaacagg atcaggccaa attcctgaat
    29281 aacatgcagc atatcgctac ttaatgtcat ccccgcctga gaaacaaaat ggccgacgat
    29341 gatcccacca aacagcacgc cgccaatacc taatcctatg ccgcgaaatt tgacgttgcc
    29401 gataaacaaa ccgacgactg ccaccaaagc cagaatactg accgttaatg ctatatcact
    29461 catcgtccat ttctcttgag ataacatttt aattgctacg gattatggct gaatcggtga
    29521 agcagatttg ccttatagcg cacattatca cgggaaagaa cgtgccgaaa tatcttaaac
    29581 agtcgaaatt taacgcattg ttgagtaagt aagacaaaaa aagccccacc agaatggcgg
    29641 ggcaaagaga atagctagtt agctatttaa cgcgggacgt tcgctgatag cgatacgctg
    29701 cgctgcgatg ggttcaggct cattacgaat taaatcaata tgcagtaaac cgtttacgaa
    29761 ggttgcgcca gagacttcca tattttcagc cagcgtaaag ctcaggctaa atggctgatt
    29821 cataagccct tgatgcagcc attttttctc ttcttttggc tgctccggcg tgccttttac
    29881 gctcaggcgc gtaccttcca gttgaatctc taaatcttcc tgacggaaac ctgccagcgc
    29941 aagggtaatg cggtagtggt tatcgtcgct tttctcaatg ttgtacggcg ggaagctctg
    30001 gctttcaccg gcgttttgca gtgcgttggc cagtttgtca aaaccgatcc attgacgcat
    30061 cagtggggat aaatcgaagt tacgcatagt catttctcct tctaagaagc gagtaagtac
    30121 ctgcaaatcc gaagattcgc atatgctccc tgacggcgag catggagatg tcaggccgcg
    30181 ccaggcggcc ttagggaatt agttgatttc gatacggcgc ggttttttcg cttccggaat
    30241 cacgcgttcg agatcgatat acagcaaacc atttaccagg ttagcaccac gaacatgaat
    30301 gttctcagct aactggaatt tgcgttcaaa gttgcgttca gcgatgccct ggtacagata
    30361 ggtgcgctct ttttgttcgt cggcgtgagc acctttcacc accagcagat tatcctgggc
    30421 ggtaatttcc agttcgctct cagcaaaacc agccacagcg atagcaatgc ggtaatggtt
    30481 ttcgtctacc agttcaacgt tatacggagg gtagccgcca ttactctggc tctggttgtt
    30541 ttctaagtgg ttaaacaaac ggtcaaatcc aatagcagaa cggtaaagcg gggataaatc
    30601 aaagttacgc ataatcaata gctcctgaaa tcagcgagaa tgtaagacct tccacaatgg
    30661 acaggtcagg tagccagaac acccatcagg cgcgtcctca tcggctacga tgtaaaaatg
    30721 ggtctggaaa tgaacttttc aagccttatc agcggacttt tttttgcagt ttatggtcta
    30781 ttgcatagac tgagggggca gcacgaaacg ttaaagtgcg atagccgcca cagtgcgacg
    30841 taatgatgat gttattttca gcaagggatc gctataactc atcaggccaa cacccacgat
    30901 caacagatga atttattatg ataagaaatg tgttgttagc gttcatgata tgcagcggaa
    30961 tgacattact cggaggatgc tccagcgtga tgtcccatac cggagggaaa gaaggaacgt
    31021 atcccggcac ccgcgccagc gcaaccatga ttggcgacga tgaaaccaac tggggcacta
    31081 agtcgctggc gattctcgat atgccgttta ccgctgtgat ggacacgctt ttactgccgt
    31141 gggatgtgtt ccgcaaagac agctcggtgc gctcgcgcgt tgaaaaaagc gaagccaacg
    31201 cgcaagccac caatgcggtt attccaccgg ccagaatgcc tgataactga tttagcgatc
    31261 agtttcggtg atccacagct ggccgccttc catccacgcc agccactgac catccggcga
    31321 gaagaccacg gcgtccgcag aaggtgaatt ggcgtggtgt tcggttaaat actcaacctc
    31381 gccgctttgc gcatgggcac aagcaattcg attatccagc acaaagccca accattctcc
    31441 tgacggatgc cagttaaatg cagactgaat atccgttttg ttatgggtta actggcgcgg
    31501 ctcgccgccc tgtggcgaga taagccacag ttgcacaatg ccgttatcat ctcgcattaa
    31561 aaacgcgatt tgtgtaccct gcggattaca gcgcacccag tggcgcggga cgttgactaa
    31621 ccccggataa gcccgatggt gggtaaaggt taaacgtcgc tgcacgacgc cacgcggtgg
    31681 cgcgggcagg gttgtttccg ttccgcttaa cggcgcatca cctgccgctt tccagccagc
    31741 ttcatcttgc ggtaactcaa cgataaacag ctccggcact ttctcgccct ttggcgaaag
    31801 tgtgtcgcca ataaatgcca gcgcgtgatt tcctacccat ccttcttcat aagcacgatt
    31861 gatttcatca ctgccaggct gtggcgtggg cgtggttttg ctcaccagca cgcaccagtg
    31921 gctaccgctg tattcacgcg gatgctgctt ttgtacgttg accgggccaa acggcgcagc
    31981 aacaccgacg tttcgcaaat ccagcgccgg atcgagttca tgcattacat ggtcgttata
    32041 ggtaaagctc accctttcac cgttcgggct aaagacatgc acatggctgc cgccgcgcag
    32101 cactcctggc gtatacggcg cggtaatatc catcgcatca aggttactca tcttgccgcc
    32161 ttcaacaatc actccgcgcc gatgatggaa gtcgtaatgc catgtttcat caggattttc
    32221 cgggccgtgg atgaaaacat atttctctga cttcggatga acggtcacca cgccgacgtg
    32281 tgcgccctgt gacgcgcgat agataacctc gacctcgccg gtatggatat tcacacgctc
    32341 aatggtctcg ccggtaaacg acgcgccaga aggacgcacg tcaaatacca gccactggct
    32401 gtcgggcgtc caggtattgg tattggtgag caggtgatta cggggagcaa aggttatctg
    32461 tttcatggcg cggtcctgat acaaaacggg tcccgccatc atacttcaca aggacttcac
    32521 tttcagacaa tagtcttttg ccatcgtgat gaatgtgagt gaaaagatgg aacatttcga
    32581 cgtggcgatt attggcctcg gcccggtagg atcggcgttg gcacgaaagt tagcaggcaa
    32641 aatgcaggtg atcgcgctgg ataaaaagca ccagtgtggt actgaaggtt tcagcaaacc
    32701 ctgcggcggt ctgctggcac cggacgcgca gcgatctttt attcgcgatg ggctgacgct
    32761 tcctgtcgat gtgatcgcta atccgcagat tttcagcgtc aaaaccgtcg acgtcgccgc
    32821 atcgctcacg cgtaactacc agcgaagcta tatcaatatt aatcgccatg ctttcgactt
    32881 gtggatgaaa tcgctgatcc ccgccagcgt tgaggtttat cacgacagcc tgtgccgaaa
    32941 aatctggcgt gaggatgata aatggcatgt catttttcgt gcagacggct gggagcaaca
    33001 tattaccgcc cgctatctgg tcggtgccga tggcgcaaac tcgatggtgc ggcgacatct
    33061 ctacccggat catcaaatcc gtaaatatgt cgctatccag cagtggttcg cggagaaaca
    33121 tccggtgccg ttctactcct gcatctttga taattcgata actaactgtt attcatggag
    33181 tatcagcaaa gacggttatt ttatctttgg cggtgcctat ccaatgaaag acggtcagac
    33241 gcgtttcacg acgctgaaag agaaaatgag cgcctttcag ttccagtttg gtaagacggt
    33301 gaaaagcgaa aaatgcacgg tgctgtttcc ctcgcgctgg caggattttg tctgcggtaa
    33361 ggacaacgcc tttctgattg gtgaagcggc gggatttatc agcgccagct cgctggaggg
    33421 gattagctat gcgctggata gcacagacat tctgcgttcg gtgttactga agcagccaga
    33481 gaagctcaat accgcttact ggcgcgccac ccgcaaactg cgtttaaaac tcttcggcaa
    33541 gatagtaaaa agccgatgcc tgaccgcacc ggctttaaga aagtggatta tgcgcagtgg
    33601 tgtggcacat attccacagt tgaaggatta gccaacgcgc ttcacatcgc ccaccagcag
    33661 gatataagag agcgcgccaa tcaacgcgac ggcggagata taaaccagtg caggtgcgaa
    33721 accgtaaccc tgcgccaggt accccaccac cagcggaacg gtgatgccgc ccagaccacc
    33781 ggcgaagtta aacacgccgc cggttaaacc aatcaggcgc atcggtgcca gagaagaaac
    33841 cagcgaccag gtaatcgaag caaaaccgtt accgaagaat gccagcgcca tcaggcacat
    33901 aatcatcatc ggatcgttag tgtagttagc gcccataatg caggtggaga tcagcaagcc
    33961 gcagataatc ggcgttttac gcgcaaagcc cagtgaaaag cccttacgta ccagcagatc
    34021 cgctacccag ccagagagca ggacgccgac aaacgccgcg aggaatggca ccgtggtcat
    34081 aaagcctgct ttcagcgccg tgattccttt ttcctgggtt aaatagttcg ggaaccaggt
    34141 taagaaaaac cacagtgtag aagccaccgc aaattgccca agataaacgc cgatcagttt
    34201 acgatggaac accagtttcc agtctttggc tgttaacggc tgacgcgcct ctttcttcac
    34261 cggcgcatca ccatccacca gaccgccgcc atcacgaatg taatccagtt cagctttgct
    34321 gatacctttg gtcaggcgcg gcggctgata aaccttaaac caaatcagcg accagataat
    34381 gccgatacca ccagtgacaa tgaacaccca gtgccagctc aacatctcct gaatccagat
    34441 cagcagcggc gtcagaaacg ccagaccgac aaactgacca gacgtataaa aaccaacggc
    34501 agaagcgcgt tcatgttccg ggaaccagct ggtcaccatc cggttattgg tcgggaaagc
    34561 aggcgcttcg aaaataccgg ttatcgcgcg cagaccaatt aatgacatta agcccgtggc
    34621 aaagccctgg aataaagtcg ccactgacca gccaaatatc gcaataaaat aagtcacgcg
    34681 agaacctacg cgatctaaaa accaaccgcc ggggatctga catagcgtat aaagccaggc
    34741 gaaggccgaa aatacatagc ccatttccgc tttggtaatg ccgaactctt cctgaatatg
    34801 ggcggaagcc acggccaggt tggcgcggtc gacataacaa atgactaccg taataaagat
    34861 catcaccagc gtcagataac gccgacgccc cggctttgct gcattaacgg gaatatccat
    34921 agcgagcttt ctccagattt tgggcatagc gaagccgctc accatgccct gtaatttaca
    34981 gagggttata tttttgtatt gctgttttag tgcccgatga ggggcttacg tggcaggaat
    35041 taccactctg ctacgctgtt atcttcatga cgccagagcg gattacgcca gtccggggca
    35101 tttttactga actcaatcac tttagcttcg tcgatttcca cgcctaagcc cggtttcgtt
    35161 aacggtttaa agaagccgcc gaccatgctg aagtcttctt tgtttttcac aaagtcgagt
    35221 aactccgcgc ctttgttgta atgaattccc atactttgtt cctgaagtac ggcgttatag
    35281 gaaacaaagt cgatatgcag gcaagccgcc agtgcaatcg gtccgagcgg acagtgcggc
    35341 gcaagggtca cgtcataggc ttctgccatt ccggcgattt tgtagcattc ggtaataccg
    35401 cccgcgtggg agagatccgg ttgcagaatc gaaataccac ctgcctccag cacgcgttta
    35461 aaatcgaagc gtgagaacat gcgttcaccc gccgccagtg gaatatgcgt ttgtgccgcc
    35521 agtttcgggt agtattcggc ttgttccgcc agcaccggct cctcaataaa cagcgggcga
    35581 tacggctcca gttctttaat cagcactttc gccatcggcg cgctgacgcg accgtggaaa
    35641 tcaagaccaa actcaatctg attgccaaaa gcttcacgaa tttgtgccac ggtgttaacc
    35701 gccgcatcta ccgcgcggga gttatcaatt agccccagtt cttcacaacc gttcagtttg
    35761 aaggtatcga agccgatttc gcgtagcgtt ttaatgccgt cgataacatc cgccggacga
    35821 tcgccgccaa cccaactgta ggctttaatt ttgtcgcgaa ccaggccgcc catcagttgc
    35881 cagaccggcg cattcagcac tttacctttg atatcccata acgcctggtc aatcccggcg
    35941 atggcgctca tcaggatcgg accgccgcga tagaatccgg cgcgatacat cacttgccat
    36001 aagtcattga tgcgcgatgg atcctgacca atcaaatagt cacccagctc gtgaactgcc
    36061 gcttccaccg tacgggcgcg gccttcgatc acgggctcgc cccaaccgac cacgccttca
    36121 tcggtttcaa ttttcaggaa catccagcgg ggaggtaaac gatacgtggt aattttggtg
    36181 attttcattg cactgcctct cgatacgcct taacaaatgc tgctgcctgc tgcgcggtgc
    36241 gctctacgga ttgcccggcg cgatagagat cgctgcctaa gcccgcccct gcacaacctg
    36301 cgtctatcca ctgcgccagg ttttctggcg tcacgccgcc aacggcaaag actgcgatgt
    36361 ccgatggcaa taccgctttt aacgctttga tgtattgcgg accaaaagcc gatgacggaa
    36421 atattttcag cgcctgcgcg cccgcttcga gcgcggtaaa ggcttcggtc gccgtcgcgc
    36481 agccggggca gacggtcatg ccgtagccca ccgcacggcg gatcacttca ctatggatat
    36541 tgggcgtaac gatgagctga cagcccatcc tggcgagcgc atcgacctgt tcaggtttca
    36601 gtaccgtacc tgcgccaatc aacgccttgt cgccgtacgc atcaacgatg gcgggaatgc
    36661 tttgctccca ttgtggggaa ttcagcggga tttcaaccgc gtcgaacccg gcgtcaatca
    36721 ccgcgccaac atgcgccagc gcctcgtcgg gcgtaatacc gcgcaaaatg gcgatcagcg
    36781 ggagtttagt ttgccactgc atgagcgatg ctccttatac cagcctgaaa tgccgtgtcg
    36841 cccgccaccg ccgtcacgtc gcaacccatc gcctgaaagg cttgctggta gcgcgcggtc
    36901 agcgatgttc cggcgacaag ggtgatggcg tgttgatggg ccacatagtc gcgcatactg
    36961 gcgacctctg cgccaatcaa caaaccagag agaaattcgc tgacctgttc gcggggaagt
    37021 gttcccagca catgcgaggc gcgaacttca aaaagctgcg gcaatatggc gggcgtatta
    37081 agaccacgct caaggccagc tgtgaaggca tcggcagagt tttcctgcgg cggcaaacct
    37141 gcgccaatca atgagtgatt taacagtaaa tgatgtaatt caccggtcat cacggtgcga
    37201 aaatcgttga tttgctggct atcggcctgc acccatttgc aatgggttcc gggcatgaca
    37261 taaagagagg aaggagccag agctcgcgcg ccgatcaatt gtgtttcttc gccgcgcatc
    37321 acattgtggt tatcgtcatg agagacacat aatccgggaa taatccagat attgtcgcca
    37381 actgacgtta attgttcgcc aatagacgaa aaacaggcag gaacagataa atacggtgca
    37441 actttccagc cgacgttgct gccaaccatt cctgccatta ccactggcgt tttctcttca
    37501 cgccagtcgg tcgtgacttc tgctaacacc gcagccggag attttccgtt caggcgcgtg
    37561 acgcctgctt ctgattgcct gctctccagg cagtggtcgc cctgataaag ccaggcgcgc
    37621 agattggtcg atccccagtc aattgcgatg tagcgagctg tcatgtgatt tcctttaacc
    37681 ttcgtgtcga gctggcgatc atggtaagcg ccgcctgctc tgccgcatcg ccgtcctgat
    37741 gtcgtatcgc atcgaacagc gccttatgtt cctggagcgt ttgcggcatg ttggcctcat
    37801 cgcccatcca ggttcgttca aaaaccgccc gctgcagcga actgatcgca atgctaagtt
    37861 gctgtaacac cgggttatgc accgactgca gcaccgcctc gtggtagcga atatccgctt
    37921 cgttaaacgc ttcgcggtcc tgattgttgg caatcatctc gttcagcgcc gattcaatct
    37981 gcgccagatc gctggaagtc gcgcgctctg ctgcccaacg ggcaatcgcc ggttccacca
    38041 gatttcgcac ttcgctcatg gcactgataa gccgtgggtc gtagtcattt tccagcaccc
    38101 attgcagtac gtcagtgtcg aggtaattcc actggttacg cggtgccaca aacgccccgc
    38161 gataacgttt catttcaatc agccgcttcg ccatcagcga acggaacacc tcacggatga
    38221 tgttgcgcga ggttgcaaac tcctcacaga gttccgcctc agccggaagc ggcgagcctg
    38281 gcacgtattt gccgtgaacg atctgtttac ccagcgtaat gacaatgcga tcggttttat
    38341 tgagagtcat ggagagtcct tgtgctctgt atgttcttct ctactttacc ccgatcgatg
    38401 cataacgcgg caactttgta gtaccagcgt gatgacgttc gcgtttgccg tgcgtgtaat
    38461 gtagtacaaa cttatattgt tgtactacaa tttagatcac aaaaagaaca atgcataaaa
    38521 aaatgacatg cgtcgggcag aaatctgaaa agggatatca ggcgctaaac aggagggaaa
    38581 gaagagtatg ctttcaacgg cttagctact cgtttaaagg attaatcatg aagttgaatt
    38641 ttaagggatt ttttaaggct gccggtttat tcccactggc gctgatgctt tcaggctgta
    38701 tctcgtatgc tctggtttcc cataccgcaa agggtagttc aggaaagtat caatcgcagt
    38761 cagacaccat cactgggcta tcgcaggcaa aagatagtaa tggaacaaaa ggctatgttt
    38821 ttgtagggga atcgctggat taccttatca ctgatggtgc cgatgacatc gttaagatgc
    38881 tcaatgatcc agcacttaac cggcacaata ttcaggttgc cgatgacgca agatttgttt
    38941 taaatgcggg gaaaaagaaa tttaccggca caatatcgct ttactactac tggaataacg
    39001 aagaagaaaa ggcactggca acgcattatg gttttgcctg tggtgttcaa cactgtacca
    39061 ggtcactgga aaacctaaaa ggcacaatcc atgagaaaaa taaaaacatg gattactcaa
    39121 aggtgatggc gttctaccat ccatttaaag tgcgatttta tgaatactat tcacccagag
    39181 gcattccgga tggtgtttcc gcagcattac tgccagtgac tgttacgctg gacatcatta
    39241 ctgcaccgct gcaatttctg gttgtatatg cagtaaacca ataatcagta agcgggcaaa
    39301 cgcgtttatg ctgtttgccc gcccacagat taattcagca catacttctc aatagcaaac
    39361 gccacgccat cttcaaggtt agatttggtg acaaagttcg ccacttcttt cactgaagga
    39421 atagcgttat ccatcgccac accgacgcct gcatattcaa tcattgcgat atcgttttcc
    39481 tgatcgccaa tcgccatgat ttcttccggt ttaataccta acacgtcggc cagtgatttc
    39541 acccccgtac ctttgttaac gcgtttatcg aggatttcga ggaagtacgg cgcacttttc
    39601 agcacggtat atttctcttt cacttcctgc ggaatacgcg cgatagcctg gtcgaggatg
    39661 gcgggttcat caatcatcat cactttcagg aactgggtat tggggtccat tttctccgct
    39721 tcgcagaaca ccagcggaat ggtggcaacg aaggattcat gcaccgtgta gtagctgata
    39781 tcacggttgg cggtgtacag cgtggtgcgg tccagggcgt ggaaatgaga accgacttcg
    39841 cgagagagtt tttccaggaa acgatagtcg tcatagctga gagcagtttg cgccacggtg
    39901 ctaccatcag cggccttctg taccagcgcg ccgttataag taatgcagta gtcgcccggc
    39961 tgttccatat gcagctcttt caggtagttg tgcacacctg catacgggcg acccgtcgtt
    40021 agcacgacat tcacgccacg ggcgcgagct gcggcaatcg catttttaac ggcgggtgaa
    40081 atggtgtgat cgggcagcag aagggtgcca tccatatcga tagcaatgag tttaatagcc
    40141 atgagttccc caggtagatt ggttcctgac ccatgctaac gcgattccgc tcaaaaatca
    40201 gtacaacacc cgagggaaaa gggggatgca acgcgcgttg cgtgctccct ttttgcttag
    40261 cggaagagtt tccctttcag cagttccatg cctgcggaaa gcagatcgtt attggcttgt
    40321 ggtgacactt caccttgcgg tgagagcgca tcaataatct tcggcaattg ttctgccagt
    40381 aaactggaag ctgtactggt atccacgcca agtttttgcc cgagatcgga caccgcattt
    40441 gtgccgagcg ccgattccag ttgctcgcca ctaaccgatt gattgccctg ttgattactc
    40501 agccaggttg agagaatggc ccctaagccg ccactttgca gtttttccag cagcacctga
    40561 atgccgccct gctcctcaac ccaacttaaa atagcctgat atttccccgc atcgcctttc
    40621 agaaaggcac cgacaacttc atcaaaaagc cccatgataa tcacctgtaa agcgttacgt
    40681 gttgacccaa aaagtataga tttgcgggat gataattgcg gattgcagaa ataaaaaggg
    40741 cggagatgat ctccgccctt ttcttatagc ttcttgccgg atgcggcgtg aacgccttat
    40801 ccggcctaca aaatcatgaa aattcaatac attgcaagat tttcgtaggc ctgataagcg
    40861 tagcgcatca ggcacgctcg catggttagc gccattaaat atcgatattc gccgctttca
    40921 gggcgttctc ttcaataaac gcacggcgcg gttcaacggc gtcgcccatc agcgtggtga
    40981 acaactggtc ggcagcaatc gcatctttaa cggtaacgcg cagcatacga cgactttccg
    41041 ggtccatagt ggtttcccac agctgttccg ggttcatctc gcccagacct ttataacgct
    41101 ggatggagag gccgcgacgg gactctttca ccagccagtc cagcgcctgc tcgaagctgg
    41161 ctaccggctg acgacgctcg ccacgttcga taaacgcatc ttcttccagc aagccacgca
    41221 gtttctcacc cagcgtgcag atacgacgat attcgccacc ggtgataaac tcgtgatcca
    41281 gcggatagtc agtatccaca ccgtgggtac gcacgcgaac aatcggctcg aacaggtttt
    41341 gctcagcatt ggtgtgaaca tcaaacttcc actggctgcc gtgctgttct ttgtcgttca
    41401 gttcgctgac cagcgcgttc acccagcggg taacggtctg ctcatcagaa aggtcagctt
    41461 ccgtcaacgt cggctgatag ataagctctt tcagcattgc tttcggataa cgacgctcca
    41521 tacgattgat cattttctgc gtcgcgttgt actcagatac cagtttctct aacgcttcgc
    41581 cagccaatgc cggtgcactg gcgttggtgt gcagcgttgc gccgtccagc gcgatagaga
    41641 tctggtactg atccatcgct tcgtcgtctt taatgtactg ttcctgcttg cctttcttca
    41701 ctttgtacag cggcggctga gcgatgtaga cgtgaccgcg ttcaacgatt tccggcatct
    41761 gacgatagaa gaaggtcaac agcagcgtac gaatgtgcga gccgtcgacg tccgcatcgg
    41821 tcatgatgat gatgctgtga taacgcagtt tgtccgggtt gtactcgtca cgaccgatac
    41881 cacagccaag cgcggtgata agcgtcgcca cttcctgaga agagagcatc ttatcgaagc
    41941 gcgctttctc gacgttgagg attttaccct tcagcggcag aatcgcctgg ttcttgcggt
    42001 tacgcccctg cttcgcagag ccgcccgcgg agtccccttc caccaggtac agttcggaaa
    42061 gcgccggatc gcgttcctgg cagtctgcca gtttgcccgg caggcccgct aagtcgagcg
    42121 cacctttacg gcgggtcatt tcacgcgcgc gacgcgccgc ttcacgggca cgggcagcat
    42181 cgataatttt gccaaccacg attttcgcgt cggttgggtt ttccagcagg tattctgcca
    42241 gcagttcgtt catctgctgt tcaaccgccg atttcacctc agaagaaacc agtttgtctt
    42301 tggtctggga ggagaatttc gggtccggca ctttcacgga aacgaccgca atcaggcctt
    42361 cacgcgcatc gtcaccggtg gcgctgactt tggctttttt gctgtagcct tctttgtcca
    42421 tgtaggcgtt cagggtacgg gtcatcgccg cacggaagcc tgccaggtga gtaccgccgt
    42481 cacgctgcgg aatgttgttg gtaaagcagt agatgttttc ctggaagcca tcgttccact
    42541 gcaacgccac ttcgacgcca ataccgtctt tttcagtgga gaagtagaag atattcgggt
    42601 ggatcggcgt tttgttcttg ttcagatatt caacgaacgc cttgatgccg ccttcatagt
    42661 ggaagtggtc ttctttgccg tcgcgcttgt cgcgcagacg aatggaaacg ccggagttga
    42721 ggaacgacaa ctcacgcaga cgtttcgcca gaatttcata ttcgaactcg gtcacattgg
    42781 tgaaggtttc gaggctgggc cagaaacgca ccatggtgcc ggttttttca gtctcgccgg
    42841 taaccgccag cggggcctgc ggtacaccgt gttcgtagat ctgacggtga attttaccct
    42901 cgcgctggat aaccagctcc agtttttgcg acagggcgtt tactaccgaa acaccaacgc
    42961 cgtgcagacc gccggacact ttataggagt tatcgtcaaa tttaccgcct gcgtgcagaa
    43021 cggtcatgat cacttccgcc gccgatacgc cctcttccgg gtgaataccg gtcggaatgc
    43081 cgcgcccgtc atcctgtaca gagacagagt tatcggcgtg aatggtgacg ataatttctt
    43141 tacagtgacc cgcgagcgct tcgtcgatag cgttatctac cacctcgaat accatgtggt
    43201 gcagaccggt gccgtcatcc gtgtcgccga tatacatacc cgggcgctta cgcaccgcat
    43261 ccagcccttt caggactttg atactggagg agtcataaga attcgacatc aacgtttctc
    43321 gctcatttat acttgggtta atccgttatt ttaccctttt ccacggtaaa catcttcgaa
    43381 ttttcgtccg acatgtctat aacgtgttca gcactgatcg cgctgacaaa gacctgtgat
    43441 tgcgtcgctt ttaagcggct ggcaagcagc ccgcgacgct catcatcaag ctcagaggca
    43501 aaatcatcta tcaggtagag acaccgccgc ccgctttcac gggtgaggaa ctctccttgc
    43561 gccagacgta aggcgcacat caacagctta agctgcccac gcgataaggt atcttccacc
    43621 ggcgcaccgt cggcgcgaat gcgtaagtcc gctttgtgcg ggccgtgcgc ggtgtaggtt
    43681 agctggcgat cgcgttcaaa attacgttcc agcacctcag catattctgt ctctttctcc
    43741 cagccgcgct ggaaagagaa agtcagagaa aactcaggga gaaattgctt acaggtatca
    43801 gccatatcgg ccgcgatacc ggcgctatac tccgcgcgcc aggtgctgat ttgctccgcc
    43861 agcgggatca gctctttatc ccacgggcgt agctgttcgt aacgtgtcac ctggcgcagc
    43921 gccgcattgc gctgcttgag caatcgcttg agattgctcc aggcggtgaa aaatccgggt
    43981 tcgttgtgaa agcatcccca gtcgaggaat gctcttctgt atttggggcc gccgttgagt
    44041 aaagtaaacc cttctggcgt tatcaactgc attggcatca ggtgcgccag ttccgcgacc
    44101 ttatgcccgt ctgtaccgtc gatgcggact ttgctgtcgc cctgtttgtc tttggttaag
    44161 ccaatcgctg tctcgcgctc ttcgccctgt aatcgcccgt ggagaacaaa cgcctcctgc
    44221 tcatggcgaa tgacgcgacc aatctgcaaa ctgcgaaacg cccgaccatg gccgagcgta
    44281 tagatggctt ccagcacgct ggttttgcca ctgccgttgg cacctaccag aaagttaaag
    44341 ccgggagata aggcgagatc cgcggtttca atgttgcgga aatcgcggat caacaagcgg
    44401 gtgagggaca ttacagtctc attggcatga caacataagc cgcgctctgg ctggccgcat
    44461 cttcaatctg cacgctggaa accgaatcgg tcagcatcat gcggacgttt tcgcatttca
    44521 gcgcgttcag aacatccagc acataactga cgttgaagcc gatttccatc tccgcaccgc
    44581 tataggtaac gtcgaggatc tcttccgctt cttcctgttc cgggttgttg gcggtgattt
    44641 tcagctggtt ttcgctgaca taaagacgta cgccgcggaa tttctcgtta gagagaatcg
    44701 ccgcgcgagc aaacgcctgc ttgagcagat cgcagccagc ttccagatgt ttgtccgggt
    44761 tcttcggcag aacgcggcga taatccggga agcgaccatc caccagtttg gaggtgaaga
    44821 taaagtcgcc aacgtgggcg cgaatgttgt tgctgccaat ctgtacgcgc agcggattgt
    44881 cgccgccgtc gagcatacgc atcagttcaa tcacgccttt acgcggtacg atcaccgaat
    44941 ggcttggcaa agattgacca attggcattg aacagaccgc cagacggtgg ccgtcggttg
    45001 ccacggtgcg cagttcttca ccttcggttt caaacagcat accatttaag taatagcgaa
    45061 cgtcctgatg cgccatagaa aactgggtcg cttcaatcag acgcttcatc gttgcctgcg
    45121 gcagggtaaa ttcgacttca ctctgccagt catcgaggtt cgggaaatcc gccgctggca
    45181 gggtagacag cgaaaaacgg ctacgcccgg agcgtaccag catccgttca ccttccagct
    45241 gcacggcaat ttccgcgcct tcaggcagac cacggcagat atcaaagaat ttgcgcgccg
    45301 gaacggtcgt cgctcctggc tcgtgtggct gaaccagcgc aacacgtgcc accatttcca
    45361 tctcgagatc agtaccggtc agcgacaacg taccgtcagc aacctgtaac agcagattac
    45421 cgagaatcgg tagcgtagga cgaccaccta acggaccgct cacctgttgt agcggtttta
    45481 ataaatgctc acgttctacg gtaaatttca taggtttacg atgacaatgt tctgattaaa
    45541 tttgaaaaat cttctttgat atcgtggctc tcttcacgca actgctcgat cttacggcag
    45601 gcatgaagca ccgtcgtgtg gtcacggcca ccaaacgcat cgccaatctc cggcagactg
    45661 tggttagtca gctctttcgc cagcgccatc gccatctggc gcggacgcgc caccgagcgg
    45721 gatcgacgct tggaaaggag atccgcgact ttgatcttgt agtactccgc caccgtcttc
    45781 tgaatattgt cgatggtgac cagtttttcc tgcaatgcca gcaagtcgcg cagcgcctca
    45841 cgcacgaagt cgatggtgat cgcccgtccg gtaaagttgg cattggcaat gacgcggttc
    45901 agcgcccctt ccagctcacg tacgttagat cgtagacgct tggcgataaa gaacgccact
    45961 tcgcccggca aacgaatgtc gttttcgtcg gcctttttca tcaggatcgc cacacgggtt
    46021 tccagctctg gcggttcgat cgccacagtc agtccccaac cgaagcggga tttcaaacga
    46081 tcctcaacgc cgttgatctc tttcggatag cgatccgagg tgagaatgat ctgttgatta
    46141 ccttccagca gggcgttgaa ggtgtggaaa aactcttcct gagatcgttc tttattagca
    46201 aaaaactgaa tatcgtcgat cagcagtgca tctacggaac ggtagtagcg tttaaactct
    46261 tcgatcgcgt tgttttgcag ggctttaacc atgtcctgaa caaagcgctc ggagtgcata
    46321 taaaccactt tggcattcgg cttgcgcgcc ataatgccgt tacccaccgc atgcagcagg
    46381 tgagttttac ccagacccgt gccgccataa aggaacaacg ggttataggc accgccaggg
    46441 ttatccgcca cctggcgagc cgccgcgcgc gccagttggt tagatttacc ttcaacgaag
    46501 ttatcaaacg tgtgtttgac gtttacgtta gaacgatagg tcggttctgc cggggccggg
    46561 acgttatccc aacctgagcg cgtagaaggc gcagcacgtt gcggctgcgt ttgcgccacc
    46621 tgtgcagggg ccgcgacgtt gctcgtcact gccgcttgtg gcgtttgcgt caccggtttg
    46681 gtgccgactt caaaacgcag ctgtggggca tccgctccgc agaaactggt tagcagtcca
    46741 ttgatattat taaggtactt gtcccgtacc caatcgagga caaaacggtt tggcgcgtac
    46801 agggccagcg tgttatcgct cagttccgcc tgcaatgggc gtatccacat actgaattct
    46861 gtggctggta actcatcctg caatcgggca agacactgct gccaaagcga aagtgacacg
    46921 gcggactcca ctcgaacaaa agtcgataat gactaaggct gaaacattca tgattgttga
    46981 cgtacgtcga aaagaccctg cttgagggtg acgcacgaac cgctgtctgc ggttatatgc
    47041 ccgatcaaga tcctgcaaaa cgatcgggac cgcggatcat agcctaaact gcgcaagaga
    47101 tcttctgttt ctcacagatt ttcccgattt atccacagga ctttccagaa ctcgctaagt
    47161 gtaaacgatc ctgccgcgag gcgggcacga tttacgccgc atattggaaa atttaatgac
    47221 catagacaaa aattggctta atcgatctaa taaagatcca ggacgatcct tgcgctttac
    47281 ccatcagccc gtataatcct ccacccggcg cgccatgctg gtttccactg gtgtgaggtc
    47341 gtacattttc cctgcgaaaa ggtgcggaaa agcgcggtaa ataaggaaag agaattgact
    47401 ccggagtgta caattattac aatccggcct ctttaatcac ccatggcttc ggtgtccatc
    47461 gtttcatttt tcggcggata tccaataaag ccattgaatt tattcaagtt taggtagaaa
    47521 tcgccatgaa acgcactttt caaccgtctg tactgaagcg caaccgttct cacggcttcc
    47581 gtgctcgtat ggctactaaa aatggtcgtc aggttctggc acgtcgtcgt gctaaaggcc
    47641 gcgctcgtct gaccgtttct aagtaataaa gctaacccct gagtggttaa gctcgcattt
    47701 cccagggagt tacgcttgtt aactcccagt caattcacat tcgtcttcca gcagccacaa
    47761 cgggctggca cgccgcaaat taccattctc ggccgcctga attcgctggg gcatccccgt
    47821 atcggtctta cagtcgccaa gaaaaacgtt cgacgcgccc atgaacgcaa tcggattaaa
    47881 cgtctgacgc gtgaaagctt ccgtctgcgc caacatgaac tcccggctat ggatttcgtg
    47941 gtggtggcga aaaaaggggt tgccgacctc gataaccgtg ctctctcgga agcgttggaa
    48001 aaattatggc gccgccactg tcgcctggct cgcgggtcct gatagccctc attcgggtct
    48061 atcaacgcct gattagtccg ctactcgggc cgcattgtcg tttcactcca acctgttcaa
    48121 gctacggaat tgaggcattg cgcaggtttg gagtgataaa aggcagttgg ttgacggtga
    48181 aacgcgtatt aaaatgccac cctttacacc ctggtggtga cgatcccgtc ccgcccggac
    48241 catttgatac cagagaacac taacgatgga ttcgcaacgc aatcttttag tcatcgcttt
    48301 gctgttcgtg tctttcatga tctggcaagc ctgggagcag gataaaaacc cgcaacctca
    48361 ggcccaacag accacgcaga caacgaccac cgcagcgggt agcgccgccg accagggcgt
    48421 accggccagt ggccagggga aactgatctc ggttaagacc gacgtgcttg atctgaccat
    48481 caacacccgt ggtggtgatg ttgagcaagc tctgctgcct gcttacccga aagagctgaa
    48541 ctctacccag ccgttccagc tgttggaaac ttcaccgcag tttatttatc aggcacagag
    48601 cggtctgacc ggtcgtgatg gcccggataa cccggctaac ggcccgcgtc cgctgtataa
    48661 cgttgaaaaa gacgcttatg tgctggctga aggtcaaaac gaactgcagg tgccgatgac
    48721 gtataccgac gcggcaggca acacgtttac caaaacgttt gtcctgaaac gtggtgatta
    48781 cgctgtcaac gtcaactaca acgtgcagaa cgctggcgag aaaccgctgg aaatctcctc
    48841 gtttggtcag ttgaagcaat ccatcactct gccaccgcat ctcgataccg gaagcagcaa
    48901 cttcgcactg cacaccttcc gtggcgcggc gtactccacg cctgacgaga agtatgagaa
    48961 atacaagttc gataccattg ccgataacga aaacctgaac atctcttcga aaggtggttg
    49021 ggtggcgatg ctgcaacagt atttcgcgac ggcgtggatc ccgcataacg acggtaccaa
    49081 caacttctat accgctaatc tgggtaacgg catcgccgct atcggctata aatctcagcc
    49141 ggtactggtt cagcctggtc agactggcgc gatgaacagc accctgtggg ttggcccgga
    49201 aatccaggac aaaatggcag ctgttgctcc gcacctggat ctgaccgttg attacggttg
    49261 gttgtggttc atctctcagc cgctgttcaa actgctgaaa tggatccata gctttgtggg
    49321 taactggggc ttctccatta tcatcatcac ctttatcgtt cgtggcatca tgtacccgct
    49381 gaccaaagcg cagtacacct ccatggcgaa gatgcgtatg ttgcagccga agattcaggc
    49441 aatgcgtgag cgtctgggcg atgacaaaca gcgtatcagc caggaaatga tggcgctgta
    49501 caaagctgag aaggttaacc cgctgggcgg ctgcttcccg ctgctgatcc agatgccaat
    49561 cttcctggcg ttgtactaca tgctgatggg ttccgttgaa ctgcgtcagg caccgtttgc
    49621 actgtggatc cacgacctgt cggcacagga cccgtactac atcctgccga tcctgatggg
    49681 cgtaacgatg ttcttcattc agaagatgtc gccgaccaca gtgaccgacc cgatgcagca
    49741 gaagatcatg acctttatgc cggtcatctt caccgtgttc ttcctgtggt tcccgtcagg
    49801 tctggtgctg tactatatcg tcagcaacct ggtaaccatt attcagcagc agctgattta
    49861 ccgtggtctg gaaaaacgtg gcctgcatag ccgcgagaag aaaaaatcct gattcggtga
    49921 gttttcgcta aaataagggc ggtcagttga ccgccttttt tcttttcgta gggcggataa
    49981 gcaccgcgca tccgccacac aaagcaacag gaacatcatg agcgataatg acactatcgt
    50041 agcccaggcc acgcctccgg gacgtggcgg cgttggcatc ctgcgcatct ccggcttcaa
    50101 agcccgtgaa gttgccgaaa ccgtgctggg taaactgcct aagccgcgct acgccgatta
    50161 tcttccgttt aaagacgccg acggcagcgt gctcgatcag gggattgcgc tatggttccc
    50221 tggcccgaac tcgttcaccg gcgaagatgt gctggaactg caaggtcatg gcggtccggt
    50281 gatcctcgac ctgctgttaa aacgcattct gaccattccc ggcctgcgga ttgctcgccc
    50341 tggtgagttt tccgaacgcg cgtttcttaa cgataaactt gacttagccc aggccgaggc
    50401 gattgccgat cttatcgacg ccagttcgga acaggcggcc cgttcggcac ttaactcgct
    50461 gcaaggcgca ttctccgcac gggttaatca tctggtagaa gccctcaccc acttgcgcat
    50521 ttacgtcgaa gcggcaattg atttccccga tgaagagatc gatttcctct ccgacggaaa
    50581 aattgaagcc cagctcaatg acgttattgc cgatcttgat gcagtgcgtg ctgaagcacg
    50641 tcagggtagt ttgttgcgcg aagggatgaa agtggtgatt gccggacgtc ctaacgccgg
    50701 taaatcgagc ctgttaaacg cgctggcggg gcgtgaagcg gcaatcgtaa ccgatatcgc
    50761 cggaactacg cgtgacgtgc tgcgtgagca tatccacatt gacggaatgc cgctgcatat
    50821 catcgatacc gccgggctac gtgaagccag tgacgaagta gaacgtattg gtatcgagcg
    50881 cgcgtggcag gaaattgaac aggccgaccg cgtgctgttt atggtcgatg gcaccacaac
    50941 agacgccgtg gatccggcag agatctggcc ggaatttatt gcccgtctgc cagcgaaact
    51001 gccgatcacc gtggtgcgca ataaagccga tatcaccggc gaaacgctgg gaatgagtga
    51061 agtgaacggt cacgcgttaa ttcgtctctc ggcaaggact ggtgaaggcg tggacgtgct
    51121 gcgtaaccat ctcaaacaga gcatgggctt tgacaccaac atggaaggcg gcttcctggc
    51181 gcgtcgtcgc cacctacagg cgctggaaca ggcagcggaa catctacaac agggcaaagc
    51241 gcaactgttg ggagcctggg caggtgaact gctggcggaa gagttgcgtc tggcacagca
    51301 gaacttaagc gaaatcaccg gggaatttac ttcagacgac ctgctggggc ggattttctc
    51361 cagcttctgt attggtaagt aaccgcgctt acgaagccgc attctgactg tcagatgcgg
    51421 cttcgcttca ttgttaccac tcctgttatt cctcaaccct ttttttaaac attaaaattc
    51481 ttacgtaatt tataatcttt aaaaaaagca tttaatattg ctccccgaac gattgtgatt
    51541 cgattcacat ttaaacaatt tcagaataga caaaaactct gagtgtaata atgtagcctc
    51601 gtgtcttgcg aggataagtg cattatgaat atcttacata tatgtgtgac ctcaaaatgg
    51661 ttcaatattg acaacaaaat tgtcgatcac cgcccttgat ttgcccttct gtagccatca
    51721 ccagagccaa accgattaga ttcaatgtga tctatttgtt tgctatatct taattttgcc
    51781 ttttgcaaag gtcatctctc gtttatttac ttgttttagt aaatgatggt gcttgcatat
    51841 atatctggcg aattaatcgg tatagcagat gtaatattca cagggatcac tgtaattaaa
    51901 ataaatgaag gattatgtaa tggaaaactt taaacatctc cctgaaccgt tccgcattcg
    51961 tgttattgag ccagtaaaac gtaccactcg cgcttatcgt gaagaggcaa ttattaaatc
    52021 cggtatgaac ccgttcctgc tggatagcga agatgtgttt atcgatttac tgaccgacag
    52081 cggcaccggg gcggtgacgc agagcatgca ggctgcgatg atgcgcggcg acgaagccta
    52141 cagcggcagt cgtagctact atgcgttagc cgagtcagtg aaaaatatct ttggttatca
    52201 atacaccatt ccgactcacc agggccgtgg cgcagagcaa atctatattc cggtactgat
    52261 taaaaaacgc gagcaggaaa aaggcctgga tcgcagcaaa atggtggcgt tctctaacta
    52321 tttctttgat accacgcagg gccatagcca gatcaacggc tgtaccgtgc gtaacgtcta
    52381 tatcaaagaa gccttcgata cgggcgtgcg ttacgacttt aaaggcaact ttgaccttga
    52441 gggattagaa cgcggtattg aagaagttgg tccgaataac gtgccgtata tcgttgcaac
    52501 catcaccagt aactctgcag gtggtcagcc ggtttcactg gcaaacttaa aagcgatgta
    52561 cagcatcgcg aagaaatacg atattccggt ggtaatggac tccgcgcgct ttgctgaaaa
    52621 cgcctatttc atcaagcagc gtgaagcaga atacaaagac tggaccatcg agcagatcac
    52681 ccgcgaaacc tacaaatatg ccgatatgct ggcgatgtcc gccaagaaag atgcgatggt
    52741 gccgatgggc ggcctgctgt gcatgaaaga cgacagcttc tttgatgtgt acaccgagtg
    52801 cagaaccctt tgcgtggtgc aggaaggctt cccgacatat ggcggcctgg aaggcggcgc
    52861 gatggagcgt ctggcggtag gtctgtatga cggcatgaat ctcgactggc tggcttatcg
    52921 tatcgcgcag gtacagtatc tggtcgatgg tctggaagag attggcgttg tctgccagca
    52981 ggcgggcggt cacgcggcat tcgttgatgc cggtaaactg ttgccgcata tcccggcaga
    53041 ccagttcccg gcacaggcgc tggcctgcga gctgtataaa gtcgccggta tccgtgcggt
    53101 agaaattggc tctttcctgt taggccgcga tccgaaaacc ggtaaacaac tgccatgccc
    53161 ggctgaactg ctgcgtttaa ccattccgcg cgcaacatat actcaaacac atatggactt
    53221 cattattgaa gcctttaaac atgtgaaaga gaacgcggcg aatattaaag gattaacctt
    53281 tacgtacgaa ccgaaagtat tgcgtcactt caccgcaaaa cttaaagaag tttaattaat
    53341 actacagagt ggctataagg atgttagcca ctctcttacc ctacatcctc aataacaaaa
    53401 atagccttcc tctaaaggtg gcatcatgac tgatcaagct gaaaaaaagc actctgcatt
    53461 ttggggtgtt atggttatag caggtacagt aattggtgga ggtatgtttg ctttacctgt
    53521 tgatcttgcc ggtgcctggt ttttctgggg tgcctttatc cttatcattg cctggttttc
    53581 aatgcttcat tccgggttat tgttattaga agcaaattta aattatcccg tcggctccag
    53641 ttttaacacc atcaccaaag atttaatcgg taacacctgg aacattatca gcggtattac
    53701 cgttgccttc gttctctata tcctcactta tgcctatatc tctgctaatg gtgcgatcat
    53761 tagtgaaacg atatcaatga atttgggtta tcacgctaat ccacgtattg tcgggatctg
    53821 cacagccatt ttcgttgcca gcgtattgtg gttaagttcg ttagccgcca gtcgtattac
    53881 ctcattgttc ctcgggctga agattatctc ctttgtgatc gtgtttggtt cttttttctt
    53941 ccaggtcgat tactccattc tgcgcgacgc caccagctcc actgcgggaa cgtcttactt
    54001 cccgtatatc tttatggctt tgccggtgtg tctggcgtca tttggtttcc acggcaatat
    54061 tcccagcctg attatttgct atggaaaacg caaagataag ttaatcaaaa gcgtggtatt
    54121 tggttcgctg ctggcgctgg tgatttatct cttctggctc tattgcacca tggggaatat
    54181 tccgcgagaa agctttaagg cgattatctc ctcaggcggc aacgttgatt cgctggtgaa
    54241 atcgttcctc ggcaccaaac agcacggcat tatcgagttt tgcctgctgg tgttctctaa
    54301 cttagctgtt gccagttcgt tctttggtgt cacgctgggg ttgttcgatt atctggcgga
    54361 cctgtttaag attgataact cccacggcgg gcgtttcaaa accgtgctgt taaccttcct
    54421 gccacctgcg ttgttgtatc tgatcttccc gaacggcttt atttacggga tcggcggtgc
    54481 cgggctgtgc gccaccatct gggcggtcat tattcccgca gtgcttgcaa tcaaagctcg
    54541 caagaagttt cccaatcaga tgttcacggt ctggggcggc aatcttattc cggcgattgt
    54601 cattctcttt ggtataaccg tgattttgtg ctggttcggc aacgtcttta acgtgttacc
    54661 taaatttggc taaatccttc aagaagccag ccattcgctg gcttcttgcc tctcaggaaa
    54721 tcacttatgt ccaaatggca actcgcctga tcctccttca ccacgtatgc tttgcgtcac
    54781 cttactatca ggacgcttta gcccatgtcc cgctttttga tttgtagttt tgccctggtt
    54841 ttactttatc ccgccgggat tgatatgtac ctcgttggtt taccgcgcat cgccgccgat
    54901 ctcaatgcca gcgaagcgca gttgcatatt gcgttctccg tatatctggc ggggatggca
    54961 gctgcgatgt tatttgccgg taaagtggcc gatcgttcag ggagaaagcc ggtcgccata
    55021 cccggcgcgg cgctatttat tattgcctcg gtgttctgtt cactggctga aaccagcacg
    55081 ttatttcttg caggccgatt tctacagggg ttgggcgcag gctgttgtta cgtagtggcg
    55141 ttcgctattt tgcgcgacac gctggatgat cgacgtcggg ctaaagtgct gtcattactc
    55201 aacggtatta cctgcatcat tccggtgtta gcgccagtgc tcggacatct gattatgctt
    55261 aaattcccgt ggcagagtct gttctgggcg atggcaatga tgggcatcgc ggtactgatg
    55321 ttgtctttgt ttattttaaa agaaacgcgc ccagcggccc ccgcagcttc ggataaacca
    55381 cgagaaaata gcgagtcgct gcttaaccgt tttttcctca gccgtgttgt tatcaccacc
    55441 ctcagcgttt cggtgatcct cactttcgtc aacacgtcac cggtattgct gatggaaatc
    55501 atggggtttg agcgcggtga atacgccacc attatggcgc tgaccgctgg cgtcagcatg
    55561 accgtttcat tctccacgcc atttgcgctg ggaattttta agccacgtac gttgatgatc
    55621 acctcgcagg tgttattcct ggcggcgggg atcactcttg ccgtttcacc ttcccatgcg
    55681 gtttctctgt ttggtatcac gctgatttgc gccggtttct cggtaggttt tggtgtggcg
    55741 atgagtcagg cgttagggcc gttttcatta cgcgcgggcg tagccagctc gaccttaggt
    55801 attgcgcagg tttgcggttc gtcactgtgg atttggctgg cagcggtggt tggtatcggc
    55861 gcatggaata tgctgatcgg gattctgatt gcctgtagca tagtgagcct gttgctgatt
    55921 atgttcgtcg cgcctggacg ccccgttgcc gctcatgaag aaatccatca ccacgcttga
    55981 tctcaatctg ctgctttgtc tgcaactgct gatgcaggag cgcagcgtaa ccaaagcggc
    56041 gaagcggata aacgtgacac cttcggcggt gagtaagtcg ctggcaaagt taagagcgtg
    56101 gtttgacgac ccgctctttg tgaactcacc gctgggtctg tcgcccacac cgctgatggt
    56161 cagcatggag caaaatctgg cggagtggat gcaaatgagc aacctgctgc tggataaacc
    56221 gcaccaccag acaccgcgcg gcctgaagtt tgagctggcg gcggaatcac cgctgatgat
    56281 gatcatgctt aatgcgctgt cgaaacagat ctaccaacgt tacccgcagg cgaccatcaa
    56341 attacgtaac tgggattacg attccttaga tgccattact cgtggtgaag tggatatcgg
    56401 tttttccggt cgcgaaagcc atcctcgctc gcgggagctg ttaagctcgc taccgttagc
    56461 cattgattat gaagtgctgt ttagtgatgt gccctgcgtc tggttacgca aagatcatcc
    56521 ggcactgcat caaacgtgga atctggacac cttcttacgt tatccgcata tcagcatttg
    56581 ctgggaacag agcgatacct gggcgctgga caatgtgtta caggagctgg gacgcgaacg
    56641 cacgattgct atgagcctgc cggaattcga gcagtcactg tttatggcag cgcaacccga
    56701 caatctgcta ctggcgaccg cgccgcgcta ctgtcagtac tacaatcaac tccatcaact
    56761 gccgttggtt gctcttcctc tcccgtttga cgaaagccag caaaaaaagc tggaagttcc
    56821 ttttaccctg ctgtggcata aacggaacag ccataatccg aagatcgtct ggttacggga
    56881 aaccattaaa aacctttacg cgtcgatggc ataaccgaat cgtatgaaac gcgacccaat
    56941 ttcacaataa aatgtaaaaa agttgtaata agcttgtctg aatcgaactt ttagccgctt
    57001 tagtctgtcc atcattccag taaatgatta ctcttgtatt cataatggac cattaagcat
    57061 ggagcgaaaa atggcgactc actttgcccg agggatttta acggaaggac atctgatttc
    57121 tgttcgtctc ccctcccagt gtcatcaaga agcccgaaac attccccctc atcgtcaaag
    57181 ccgttttctg gcgtccagag gtttactcgc agaactgatg ttcatgctgt atggcattgg
    57241 cgaattgccg gaaatcgtca ccctgccgaa aggtaaaccg gttttcagtg ataaaaattt
    57301 gccttcgttt tccatttcct atgccgggaa tatggttggc gtggcgttaa caaccgaagg
    57361 tgaatgtggc ctcgatatgg aactacagcg tgcgacgcgc gggtttcata gcccacacgc
    57421 gcccgataac cacacctttt ccagcaatga atcgctatgg atcagtaaac aaaacgatcc
    57481 taacgaagcg cgggcgcagc tcatcacgct gcgccgaagc gtgctaaaac taaccggtga
    57541 tgttttgaat gacgatccgc gcgatctgca gctgctgccc attgccggac gcctgaaatg
    57601 tgctcatgta aatcatgtag aagcgttatg cgacgcggaa gacgtgctgg tgtggtccgt
    57661 ggcggtcacg cccacgattg aaaagctcag tgtctgggag ttagatggca aacacggctg
    57721 gaaaagcctg ccggatattc acagccgcgc caacaatcct accagccgga tgatgcgttt
    57781 tgcccaactc tctaccgtga aggctttttc gccaaattga tagacaacca caggagtcat
    57841 catgtctgaa aaattgcagg tggttacgtt actggggagc ctgcgcaaag gctcatttaa
    57901 tggcatggtt gcacgtaccc tgccgaaaat tgctccggcg agcatggaag tcaatgcgtt
    57961 accatccatt gccgacattc ccttgtatga cgctgacgta cagcaggaag aaggttttcc
    58021 agcaacggtt gaagctctgg cggaacagat ccgtcaggct gacggtgtgg tgatcgtcac
    58081 gccggaatat aactactcgg taccgggtgg gctgaaaaat gccatcgact ggctttcccg
    58141 cctgccggat caaccgctgg ccggtaaacc ggtattgatt cagaccagct caatgggcgt
    58201 gattggcggc gcgcgctgtc agtatcacct gcgccagatt ctggttttcc tcgatgcaat
    58261 ggtgatgaac aagccggaat ttatgggcgg cgtgattcag aacaaagttg atccgcaaac
    58321 cggagaagtg attgatcagg gtacgctgga ccacctgacc gggcaattga ccgcatttgg
    58381 tgagtttatt cagcgagtta agatctaaat aaaaaacccg ccagcaatca tgcatggcgg
    58441 gtttttaacg cgctatcgat tttagtgagc gtcgataaag acaatcttca ggataaacag
    58501 cagcgcaacg atgattacgc acgggcttag atcacgcaga cgtccggtac cgattttcat
    58561 cacgcagtag gagataaagc ccagcgcgat accttcggta atcgagaagc tgaacggcat
    58621 catcacggcg gtaataaacg ccggaacaga ttcagtaaga tcctgccagt tcacgcgtgc
    58681 cagactggaa gtcatcagca cgccaacgta aatcagcgca ccagctgcag cgtagcctgg
    58741 caccatcccc gccagcggcg acagaaagat aaccagcagg aacagcagac caacaaccac
    58801 tgccgtcaga ccggtacgac cgccaaccga tacgccggaa gaggactcaa tataagccgt
    58861 aacggaagaa gtaccgataa acgaaccggt cacggaagag atactgtcga catacagcgc
    58921 ctgcttcatg cgcgggaatt tccccttctc atccgccaga cctgctttat cggtcacgcc
    58981 aatcagcgta ccggaggagt caaacaagtt gaccaacatg aaagagaaaa tcacccctgc
    59041 cagcccgagg ttaaacgacc cggctaaatc tacatgaccc acaactgtca ttacgctcgg
    59101 cggcgcagaa acgatgccat tgtagtgcac atcacccagc atccagccca gcagcgtcgt
    59161 caccacgata gaaaccagca ccgctgcgtg aatgttgcgc gaggccagaa tagcaatgat
    59221 gaagaagccg aggataccca gaagtacgct gtgagaagtc agattaccga tgctcaccag
    59281 cgtttccggg ttagcgacaa tcacacctgc gtttttcagc cccatcatgc caatgaacag
    59341 accgataccg ctggtaatac ccacacgcag actcaccgga atgttggcta tcatccagta
    59401 gcgaacgcgg aaaatcgtca gtaacagcag acctatcgcg ccccagaaga ttgcgcccat
    59461 cccgacctgc cacggcaagc ccatcgcctg tacaacgaca aaagcgaaga acgcattcag
    59521 gcccatagcg ggtgccagtg caactggcag gttagcaaac agtcccatca taatactgcc
    59581 gaatgcagcg atcagacagg tagtgacgaa gacggcgctg gtatccatgc cagcaacgcc
    59641 aagaatttgc gggttaacaa aaacgatgta aaccatcgtc aggaaggtgg taaaaccggc
    59701 gatcacttcg gtccgtgccg tcgtgccatg ttcgcgcagt ttaaacacgc gttccagcat
    59761 cccctgacca gaagtctggg tggtatgttg atgactcatt atctatttcc gaacaaggag
    59821 ggaaaatccg tcgctatcgt ataccaaaat gcgacaatag gcgcgtttgt gagagacttt
    59881 tttattggat ttacttatac ggcaacgatt gcgttgcgca aatcggctct acgaaaacgt
    59941 taaactgatt aaaaaggaaa ggcatgtccc ggatagaagc ggtatttttc gactgcgacg
    60001 gtacgctggt cgacagtgaa gtcatttgct ctcgcgcata tgtaacgatg tttcaggaat
    60061 ttggtattac gctcgatcct gaagaggtat tcaaacgttt caaaggtgta aaactgtacg
    60121 aaattatcga tattgtttcc cttgaacatg gtgttacgtt agcgaaaaca gaagctgaac
    60181 acgtttaccg tgcagaagtc gctcggctgt tcgattcaga actggaagcc atcgaagggg
    60241 ctggagcgct cctgtcagcg atcactgcgc caatgtgtgt ggtatctaac ggcccaaata
    60301 acaaaatgca gcattctatg ggcaagctga atatgttgca ctacttcccg gataaactgt
    60361 tcagcggcta cgatattcag cgctggaagc cagacccggc gttaatgttc catgcggcaa
    60421 aagcgatgaa tgtaaatgta gaaaactgca ttctggttga tgactcagtt gccggtgcac
    60481 aatctggtat cgacgcaggt atggaagtgt tctacttctg cgccgacccg cacaataagc
    60541 cgatcgttca cccgaaagtc accaccttta cccatctttc gcagttacct gaactgtgga
    60601 aagcgcgtgg ttgggatatt acggcatagt tcttcacact cccttcactt accccgctta
    60661 aattggcgct caaaggtaag taaagggagt ttgatatgtc tgtttcacgt cgggtaatac
    60721 atcacggact ttattttgca gttttaggac cgttaattgg tgttctgttt cttgtcctct
    60781 acatattctt cgcaaaagaa ccgctggttc tttgggtgat aatacatcca atttttctct
    60841 tattgtcgat aactacggga gctattcctg cgttgttaac cggtgtaatg gttgcctgtc
    60901 tgccggaaaa gatcgggtca cagaaacgtt atcgttgtct ggctggtggc ataggtggcg
    60961 tcgttatcac cgagatctat tgtgcagtta ttgtacatat taagggcatg gcttcctcgg
    61021 agttgtttga aaacattctt tctggtgaca gtctcgttgt ccgcatcatt cctgcattgc
    61081 tggcaggtgt ggtgatgagc agaatcatta cccgtctacc cggattggat atttcatgtc
    61141 ctgaaacaga ctctttaagt taagcgggat actttatctt tgggctactc aaaagcagac
    61201 aggatgtttc tatgactcaa aatatcaggc cgttacccca attcaaatat catcccaagc
    61261 cactggaaac aggcgcattt gaacaggata aaaccgtaga gtgcgattgc tgtgaacaac
    61321 agacgtcagt ttattactcg ggtccctttt attgcgttga tgaagttgaa catctctgtc
    61381 cgtggtgtat tgcggacggt tctgctgctg aaaagtttgc aggtagtttt caggatgatg
    61441 ccagcataga aggtgttgaa tttgagtatg atgaagagga cgaatttgcc ggtattaaga
    61501 acacatatcc tgatgaaatg ctgaaagagt tggttgaacg cacgccaggt tatcatggat
    61561 ggcagcagga attctggctc gcgcattgtg gcgatttctg tgtttttatc ggctatgtgg
    61621 gctggaatga tataaaagat cgcctcgatg aatttgccaa ccttgaagaa gattgtgaga
    61681 atttcggtat tagaaattct gatctagcta aatgcctgca aaagggtggt cattgtcagg
    61741 gttatctctt ccgctgtctc cactgcggca agctgagact gtggggtgat ttttcgtagt
    61801 tatttaaata atgagaacag gccggagcgt aattcacaca tccggcctta tttcttaagc
    61861 ttaaccgagt gctaattctg cggcagcggc tttatcagcg attaccatca gcgaaggatg
    61921 cagctgcaac acggaagctg gaacatcttc ggtaaccgga ccttgcagaa catttttcag
    61981 tgcctgcgct ttacccgcgc cgctgacaat tatcagcaag tttttcgccg ccatgatgct
    62041 tttcggcccc atcgtcacgt agctgtcagg cactaacgaa aagtcgccgc ccaactcgcc
    62101 atgcgccaca atatcaacca tctctccctg gatcgggaac tccacggttt gctcatggaa
    62161 atgggtcgta ttcggcaaat tgccacaaaa atgaccatct gcacctaatc ccagcaccac
    62221 caaatccagt ccgccttcac gcgccagttt ctgatcatgc tcgcggtagt tatcaatagt
    62281 gagcttctgg atattctctt ctttgatccc cgcaggggtg aaaaacagat tacgcagatt
    62341 ggtaatcgtt acgccttctc cctctttgcc gcgaaatgga atttcatcaa aattatagaa
    62401 atagcagtta tcgtaccagg gcttaccttt aaccagggtg gtgaggtatt catacatgcc
    62461 tttgggcgtg ctaccggcgg taattgccag gttaacacga cgcgtcttcg acatataacc
    62521 aagcagatgg tgtgccgcga cacggctcat ttcctggtaa tcttcggtaa tgattaattt
    62581 catcttaatg ccttatttta tttaaataat ttctgtacaa aggctgcata ggctggtcgc
    62641 cagacatcca tttcatggtt cagacccgga tattcctggt aatcaaagtt aatttttttc
    62701 tgctcaagct cagttttcag cccggcgata tccttgccgg ttacgacatc tttatccccc
    62761 acaaccacag taaaattacg tagttgctgg ttgatagctg ccggatcgtt cagtcgggcc
    62821 gcgacacctt catccggtac ggttgtcgtg gtaacaccac tgaatgtggc cagccagcca
    62881 aagctttcca gatgattcat tccggaaacc agcgcctggt acccgccttg tgaaagccct
    62941 gccagcgcgc ggccatcggc atctttacgg acattaaaac gcttgctaat cagcgggata
    63001 atatcgttca tcagttcgcg atctgccgct ttagcattca gcggataaaa gactttacgt
    63061 ctttcctgag gcacgaaatc ttcgggaata atgcccttcg catcggtttc tgtatccggg
    63121 atcaccacca gcatcggttt aattttccct tcagcaagca ggttatccat gatttgcggg
    63181 atacgcccct gatcgatagc ggaacgtccg gtatcaccaa agccgtgata gaaatagagc
    63241 actggcaaag gctcgcccat gccggtgtat cctggcgggg tccagacata catctgacgt
    63301 tcagattgca atgcgttgga gtggtaagtt atggcgatca aatcaccatg cgcaacagaa
    63361 cgcgtatcca gataactgcc tggcaccaga atcatactgg agttaacctg gcgctgaggc
    63421 ttagtcattg cggtgcctgt atcaatgctg cgtacaccat caacattgaa aaaatactcg
    63481 tacaggttgc ctttcaggat aggtgtgcgc cacgaccaga ctcctgcttc gtctttggtc
    63541 atcgggtgaa tattgtccgg aaccggaaca cccaccacta cagagacatt ttttgcccca
    63601 ggggcaaagt agcgaaaggt cacgctgtta tcggcattga cctgagtcac atactgtttc
    63661 accgggatag tgggtgccgg gctggctggc atatccgctg ctatggccca ctgagcagaa
    63721 ataccgctgg caatagccag cgttaaagca gcaattttta tattcatcgt aatattcctt
    63781 tcattaagtt ccattaccac cagatttcag ccagggcacc gacagcaaac tggtcgtctt
    63841 tattgtcttc aaaggtgaag ccatccagtt cgttttccag ggctttgata tacgtggcgt
    63901 agaaacgaat ttccggacgc gaggtcaaca tactggtatt gactttaaag gtatggaaga
    63961 gcgtggtttt ataaccagac tcattaaatt tattactatt cgcatctttg ttttgctggg
    64021 tgaaatagcc cagttcaaca cctgtctggt tatattggtc ccaaatatag gccgggcgaa
    64081 caaccgcacg aatagattcg aaatcagagt gggcgtctgt ttcgtagcta tatatatcgt
    64141 taccgaagga gtaaacaatc gcgttagcta caatgaaatg atcgccaata taggcttcgc
    64201 cctgcgaagt cagacgtacc gctgttccgc cggtgtgatc accataataa cgaccattaa
    64261 aggtggtaaa tggacttgcg ccagcataac ggccaaagtt actggcgata gagttattcg
    64321 cgaccaggaa ggagaattcg ttgaagcca
//
LOCUS       DAPHKZ010000012        64152 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.012, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000012 DAPHKZ010000000
VERSION     DAPHKZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 64152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64152
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.012"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(78..1025)
                     /gene="dusC"
                     /locus_tag="RH288_000794"
     CDS             complement(78..1025)
                     /gene="dusC"
                     /locus_tag="RH288_000794"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HDV4029885.1"
                     /translation="MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKT
                     VNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQA
                     GATELVVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQSAQQCMAISGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQW
                     LSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIEKL"
     gene            1264..1662
                     /locus_tag="RH288_000795"
     CDS             1264..1662
                     /locus_tag="RH288_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDV4029886.1"
                     /translation="MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAV
                     STLVVFLVVSWSSQLVHGERKVVGQKGSEE"
     gene            1659..2354
                     /locus_tag="RH288_000796"
     CDS             1659..2354
                     /locus_tag="RH288_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HDV4029887.1"
                     /translation="MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPF
                     LMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVA
                     MVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLI
                     APFLFPIILAVMG"
     gene            2484..3368
                     /gene="cdd"
                     /locus_tag="RH288_000797"
     CDS             2484..3368
                     /gene="cdd"
                     /locus_tag="RH288_000797"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDV4029888.1"
                     /translation="MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSA
                     TGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVH
                     AEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
                     LPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECK
                     DGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDAT
                     SATLKALGCHSIDRVLLA"
     gene            3518..4237
                     /gene="sanA"
                     /locus_tag="RH288_000798"
     CDS             3518..4237
                     /gene="sanA"
                     /locus_tag="RH288_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HDV4029889.1"
                     /translation="MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPED
                     AQGYPAVTPEQLLELQKKQGK"
     gene            4240..4479
                     /locus_tag="RH288_000799"
     CDS             4240..4479
                     /locus_tag="RH288_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HDV4029890.1"
                     /translation="MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVY
                     VWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR"
     gene            4673..5911
                     /gene="preT"
                     /locus_tag="RH288_000800"
     CDS             4673..5911
                     /gene="preT"
                     /locus_tag="RH288_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreT"
                     /protein_id="HDV4029891.1"
                     /translation="MPQQNYLDELTPAFTSLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQSGCTRAGVDAPIDIGRLQ
                     RFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAHPG
                     GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEVGNTLTLEQLKAENRAVLVTVG
                     LSSGSGLPLFEHSDVEIAVDFLQRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLG
                     CQAVTCVAREELDEFPASEKEFTSARELGVSIIDGFTPVAVEGNKVTFKHVRLSGELT
                     MAADKIILAVGQHARLDAFAELEPQRNTIKTQNYQTRDPQVFAAGDIVEGDKTVVYAV
                     KTGKEAAEAIHHYLEGACSC"
     gene            5905..7140
                     /gene="preA"
                     /locus_tag="RH288_000801"
     CDS             5905..7140
                     /gene="preA"
                     /locus_tag="RH288_000801"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HDV4029892.1"
                     /translation="MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGV
                     VFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRRLKEDYPDK
                     VLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
                     RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMP
                     IVNGKSSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGA
                     ATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANNNIVPAEDLDRSYI
                     VYPRINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGC
                     IELGEVKFKKGEKEHPVTL"
     gene            complement(7383..8393)
                     /gene="mglC"
                     /locus_tag="RH288_000802"
     CDS             complement(7383..8393)
                     /gene="mglC"
                     /locus_tag="RH288_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HDV4029893.1"
                     /translation="MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMAT
                     MPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYAR
                     KK"
     gene            complement(8409..9929)
                     /gene="mglA"
                     /locus_tag="RH288_000803"
     CDS             complement(8409..9929)
                     /gene="mglA"
                     /locus_tag="RH288_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
                     /protein_id="HDV4029894.1"
                     /translation="MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHAL
                     MGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQ
                     RSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
                     AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDE
                     VTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQ
                     PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKQINNHNANE
                     AINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDS
                     MRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIA
                     ELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQNEILRLASLHL"
     gene            complement(9990..10988)
                     /gene="mglB"
                     /locus_tag="RH288_000804"
     CDS             complement(9990..10988)
                     /gene="mglB"
                     /locus_tag="RH288_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HDV4029895.1"
                     /translation="MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVR
                     KAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
                     DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGT
                     VLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVGVDKDNLAEFSKK"
     gene            complement(11268..12308)
                     /gene="galS"
                     /locus_tag="RH288_000805"
     CDS             complement(11268..12308)
                     /gene="galS"
                     /locus_tag="RH288_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HDV4029896.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELD
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDN
                     LSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGAGT
                     PDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIP
                     IARYTDPQLTTVRYPIASMAKLATELALQGAAGNIDPRASHCFMPTLVRRHSVATRQN
                     AAAITNSTNQAM"
     gene            complement(12450..13607)
                     /locus_tag="RH288_000806"
     CDS             complement(12450..13607)
                     /locus_tag="RH288_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HDV4029897.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITP
                     RDAWTWAFLDLIGQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
                     WTPDASAILYEKYWKLHGGVEAISNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRS
                     GWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDWAYRWCAFLLQMPRELSAPF
                     QAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLGLFMHFDR
                     LELLAFVIPVWLANILFSVIWLRYFRQGPVEWLWRQLTLRAAGPAISKTSR"
     gene            complement(13624..14292)
                     /gene="folE"
                     /locus_tag="RH288_000807"
     CDS             complement(13624..14292)
                     /gene="folE"
                     /locus_tag="RH288_000807"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDV4029898.1"
                     /translation="MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHM
                     TEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAV
                     RHHN"
     gene            14550..15386
                     /gene="yeiG"
                     /locus_tag="RH288_000808"
     CDS             14550..15386
                     /gene="yeiG"
                     /locus_tag="RH288_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HDV4029899.1"
                     /translation="MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPP
                     VLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEKVANDDGYDLGQGAGF
                     YLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSVSAFAPIVNPCSVPWGIKAFSSYLGEDKNAWLEWDSCALMYASNAQDAIPTLID
                     QGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYL
                     LK"
     gene            complement(15418..17409)
                     /gene="cirA"
                     /locus_tag="RH288_000809"
     CDS             complement(15418..17409)
                     /gene="cirA"
                     /locus_tag="RH288_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HDV4029900.1"
                     /translation="MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNL
                     KDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     VDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNS
                     TTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQN
                     YSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNTVDGKYTLPLTAINQFLTV
                     GGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGE
                     HWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPE
                     TSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFET
                     GANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVSNGENKPLS
                     DLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVT
                     KDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF"
     gene            complement(17703..19172)
                     /gene="lysP"
                     /locus_tag="RH288_000810"
     CDS             complement(17703..19172)
                     /gene="lysP"
                     /locus_tag="RH288_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HDV4029901.1"
                     /translation="MVSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     QAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
                     LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLIIWFGYKLIKGTHFVRYSEMKFPQNDKK"
     gene            complement(19377..20258)
                     /locus_tag="RH288_000811"
     CDS             complement(19377..20258)
                     /locus_tag="RH288_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4029902.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNY
                     ILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLE
                     DELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLS
                     NALRRFLDYCDPANVPR"
     gene            20357..21406
                     /locus_tag="RH288_000812"
     CDS             20357..21406
                     /locus_tag="RH288_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HDV4029903.1"
                     /translation="MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGF
                     SALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGI
                     SGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAI
                     SPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGANSGEKSKITIPWFAILFIVVAI
                     FNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLI
                     VGGGAINYVIQSVIA"
     gene            21480..22337
                     /gene="nfo"
                     /locus_tag="RH288_000813"
     CDS             21480..22337
                     /gene="nfo"
                     /locus_tag="RH288_000813"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDV4029904.1"
                     /translation="MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPL
                     TTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLG
                     LSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEH
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLN
                     DAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLK
                     AQQTEKAVA"
     gene            22340..23428
                     /locus_tag="RH288_000814"
     CDS             22340..23428
                     /locus_tag="RH288_000814"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDV4029905.1"
                     /translation="MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRK
                     GRIKGKGYILTEQEYCVVVGTINMDIRGMADIRYPQSASHPGTIHCSAGGVGRNIAHN
                     LALLGRDVHLLSVIGDDFYGEMLLEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDQT
                     VLAINDTHLLEQLTPQLLNGSRDLLRHAGVVLADCNLTAEALEWVFTLADEIPVFVDT
                     VSEFKAGKIKHWLAHIHTLKPTLPELEILWGQAITSDADRNTAVNALHQQGVQQLFVY
                     LPDESVYCSEKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFLEGYSFRDSARFAVA
                     CAAISRASGSLNNPTLSADNALSLVPMV"
     gene            complement(23535..24785)
                     /locus_tag="RH288_000815"
     CDS             complement(23535..24785)
                     /locus_tag="RH288_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDV4029906.1"
                     /translation="MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGG
                     IMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVL
                     PAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFAR
                     LLSPATESSQVSFNNLSFTETPPKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFEHASLESILGYLLAPLAWVMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTAGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(24885..25826)
                     /gene="rihB"
                     /locus_tag="RH288_000816"
     CDS             complement(24885..25826)
                     /gene="rihB"
                     /locus_tag="RH288_000816"
                     /EC_number="3.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosylpyrimidine nucleosidase"
                     /protein_id="HDV4029907.1"
                     /translation="MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLD
                     KTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAEST
                     HAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
                     PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSD
                     IMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCD
                     ELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH"
     gene            25956..26654
                     /gene="yeiL"
                     /locus_tag="RH288_000817"
     CDS             25956..26654
                     /gene="yeiL"
                     /locus_tag="RH288_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311082.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator YeiL"
                     /protein_id="HDV4029908.1"
                     /translation="MKEIHNNDLKQQLMSESAFKDCFLTDVSADTRLFHFLARDYIVQ
                     EGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIE
                     ECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNSLAAFIL
                     LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFIHDGLLIKSKKGYLIKNRKQLSGLA
                     LEMDPENKFSGMMQ"
     gene            complement(26725..27975)
                     /locus_tag="RH288_000818"
     CDS             complement(26725..27975)
                     /locus_tag="RH288_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDV4029909.1"
                     /translation="MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGG
                     IMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEPSQVTFENLSFSETPPKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVA
                     YLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(28069..29007)
                     /gene="psuG"
                     /locus_tag="RH288_000819"
     CDS             complement(28069..29007)
                     /gene="psuG"
                     /locus_tag="RH288_000819"
                     /EC_number="4.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HDV4029910.1"
                     /translation="MSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFV
                     VAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSASEIARA
                     MAVKWQSGLNGGLVVANPIPEQFAMPEHTINAAIDQAVAEAEAQGVIGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLAG"
     gene            complement(28995..29936)
                     /locus_tag="RH288_000820"
     CDS             complement(28995..29936)
                     /locus_tag="RH288_000820"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HDV4029911.1"
                     /translation="MREKDYVVIIGSANIDVAGYSHESLNYADSNPGKIKFTPGGVGR
                     NIAQNLALLGNKAWLLSAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLD
                     NTGEMLVAINDMNISNAITAEYLAQHGEFIQRAKVIVADCNISEEALAWILDNAANVP
                     VFVDPVSAWKCVKVRDRLNQNHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLN
                     RLVLSMGGDGVYYSDISGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFAESV
                     RFAQGCSSMALSCEYTNNPDLSIANVISLVENAECLN"
     gene            complement(30359..32050)
                     /gene="fruA"
                     /locus_tag="RH288_000821"
     CDS             complement(30359..32050)
                     /gene="fruA"
                     /locus_tag="RH288_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HDV4029912.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMA
                     IVLGDSIPNDSALNGKNVWLGDISRAVAHPELFLSEAKGHAKPYTAPVAATAPVAASG
                     PKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
                     LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATTE
                     SKKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGS
                     AFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLIS
                     TQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAV
                     LLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMV
                     ARRKFDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIG
                     AKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPEVDAVAKAA"
     gene            complement(32067..33005)
                     /gene="fruK"
                     /locus_tag="RH288_000822"
     CDS             complement(32067..33005)
                     /gene="fruK"
                     /locus_tag="RH288_000822"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDV4029913.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            complement(33005..34135)
                     /gene="fruB"
                     /locus_tag="RH288_000823"
     CDS             complement(33005..34135)
                     /gene="fruB"
                     /locus_tag="RH288_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HDV4029914.1"
                     /translation="MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIV
                     ASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVS
                     RAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLT
                     SDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA"
     gene            34503..35684
                     /gene="setB"
                     /locus_tag="RH288_000824"
     CDS             34503..35684
                     /gene="setB"
                     /locus_tag="RH288_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HDV4029915.1"
                     /translation="MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWN
                     RNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTIEAPRRNRRDT
                     LLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKD
                     V"
     gene            complement(35681..35935)
                     /locus_tag="RH288_000825"
     CDS             complement(35681..35935)
                     /locus_tag="RH288_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDV4029916.1"
                     /translation="MECRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKI
                     FTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEMLTAP"
     gene            36090..36662
                     /gene="yeiP"
                     /locus_tag="RH288_000826"
     CDS             36090..36662
                     /gene="yeiP"
                     /locus_tag="RH288_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HDV4029917.1"
                     /translation="MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSPGEKIRIHIEERRYMGRAD"
     gene            36885..38351
                     /locus_tag="RH288_000827"
     CDS             36885..38351
                     /locus_tag="RH288_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDV4029918.1"
                     /translation="MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLT
                     DRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLN
                     AKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
                     APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHV
                     SFPGTMVDRIVPAATDESLVEISQHLGVNDPCAISCEPFIQWVVEDNFVAGHPAWEVA
                     GVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDE
                     QAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHQGRE
                     TDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLRE
                     VFGDDLPDNPHFVQAIEQAWQQIVQFGAHQALLNTLKI"
     gene            38469..39455
                     /gene="yeiR"
                     /locus_tag="RH288_000828"
     CDS             38469..39455
                     /gene="yeiR"
                     /locus_tag="RH288_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding GTPase YeiR"
                     /protein_id="HDV4029919.1"
                     /translation="MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNENFRDQLAAADIIVANKSDRTTPE
                     SEQALQRWWQQNGGDRQLIHSEHGKVDGHLLDLPRRNLAELPASAAHSHQHVVKKGLA
                     ALSLPEHQRWRRSLNSGQGYQACGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPE
                     GLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALLKLRLATTA"
     gene            39494..40207
                     /gene="lpxT"
                     /locus_tag="RH288_000829"
     CDS             39494..40207
                     /gene="lpxT"
                     /locus_tag="RH288_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kdo(2)-lipid A phosphotransferase"
                     /protein_id="HDV4029920.1"
                     /translation="MIKNLPQIVLLNIVGLALFLSWYIPVNHGFWLPIDADIFYFFNQ
                     KLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFWLKENAPGRRRIVIIGLVMLLTA
                     VVLNQLGQALIPVKRASPTLTFTDINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
                     MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDR
                     LITFFDKSLPGKNKHFQNK"
     gene            40619..41185
                     /gene="mepS"
                     /locus_tag="RH288_000830"
     CDS             40619..41185
                     /gene="mepS"
                     /locus_tag="RH288_000830"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HDV4029921.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVG
                     SETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTF
                     REQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
                     SSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            41366..42922
                     /locus_tag="RH288_000831"
     CDS             41366..42922
                     /locus_tag="RH288_000831"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HDV4029922.1"
                     /translation="MFIRAPNFGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYD
                     TLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDK
                     KTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
                     VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIA
                     GIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQ
                     FYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFEL
                     IARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERD
                     MLKEQEATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTET
                     ITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPLPLDDFVR
                     WLKKPYTPQW"
     gene            43004..44818
                     /locus_tag="RH288_000832"
     CDS             43004..44818
                     /locus_tag="RH288_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416682.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV4029923.1"
                     /translation="MIVRILLLFIALFTFGVQAQAIKESYAFAVLGEPRYAFNFNHFD
                     YVNPAAPKGGQITLSALGTFDNFNRYALRGNPGARTEQLYDTLFTTSDDEPGSYYPLI
                     AESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPVFPEKYWKDHKLSDPLATPPLASGPYRVTSW
                     KMGQNIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMEND
                     AKNWATRYTGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVREAITLAFDF
                     EWMNKALFYNAWSRTNSYFQNTEYAARNYPDAAELVLLAPMKKDLPSEVFTQIYQPPV
                     SKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQ
                     HSLQRLGINMDIRKVDNSQITNRMRSRDYDMMPRVWRAMPWPSSDLQISWSSEYINST
                     YNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAW
                     WDKFSQPAVRPIYSLGIDTWWYDVNKAAKLPSASKQGE"
     gene            44819..45913
                     /locus_tag="RH288_000833"
     CDS             44819..45913
                     /locus_tag="RH288_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HDV4029924.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GNAGVLPGAGGEGVRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHER
                     YFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNIVSDISYTLVDPRIDFEGR"
     gene            45913..46938
                     /locus_tag="RH288_000834"
     CDS             45913..46938
                     /locus_tag="RH288_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4029925.1"
                     /translation="MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIAND
                     KPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLENNGWVLWAPIRFGA
                     TSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
                     AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDA
                     FDPNKAV"
     gene            46940..48529
                     /gene="yejF"
                     /locus_tag="RH288_000835"
     CDS             46940..48529
                     /gene="yejF"
                     /locus_tag="RH288_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HDV4029926.1"
                     /translation="MTQTLLAIENLSVGFRHQQTVRTVANDVSLQIEAGETLALVGES
                     GSGKSVTALSILRLLPSPPVEYLSGDIRFHGESLLHASDQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLS
                     IVRKLAHRVAVMQNGRCVEQNYAATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLL
                     DVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGESGSGKSTTGLALLR
                     LINSQGSIIFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSAAQREQQVIAVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD
                     EPTSSLDKTVQAQILTLLKSLQQKHQLAYLFISHDLHVVRALCHQVIILRQGEVVEQG
                     PCARVFATPQQEYTRQLLALS"
     gene            complement(48533..48877)
                     /locus_tag="RH288_000836"
     CDS             complement(48533..48877)
                     /locus_tag="RH288_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029927.1"
                     /translation="MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVAL
                     KLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNYNPF"
     gene            complement(49210..50400)
                     /gene="bcr"
                     /locus_tag="RH288_000837"
     CDS             complement(49210..50400)
                     /gene="bcr"
                     /locus_tag="RH288_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Bcr"
                     /protein_id="HDV4029928.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAAAVACALANTIDQLI
                     VMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILALAAILASAMIFFLIKETLPPERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVAPENFGYYFALNIVFLFVMTIFNSRFVRRI
                     GALNMFRSGLWIQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIAFCATSSILFCLYASR
                     PKKR"
     gene            complement(50428..51123)
                     /gene="rsuA"
                     /locus_tag="RH288_000838"
     CDS             complement(50428..51123)
                     /gene="rsuA"
                     /locus_tag="RH288_000838"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HDV4029929.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPE
                     HDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDL
                     TKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGE
                     YRPLTEEEIASVV"
     gene            51272..53032
                     /locus_tag="RH288_000839"
     CDS             51272..53032
                     /locus_tag="RH288_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDV4029930.1"
                     /translation="MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAEL
                     ARLARGRVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHGKVVFGSVQSVAR
                     NLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAATRKGVMIFAATVEHAKEIVGLLPAED
                     AALITGDTPGAERDVLIENFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDTVLVDPDDMLKAALRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSERF
                     RLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADILAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRLAHELRG"
     gene            53157..53441
                     /gene="rplY"
                     /locus_tag="RH288_000840"
     CDS             53157..53441
                     /gene="rplY"
                     /locus_tag="RH288_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HDV4029931.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDH
                     DKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA"
     gene            complement(53580..54587)
                     /gene="yejK"
                     /locus_tag="RH288_000841"
     CDS             complement(53580..54587)
                     /gene="yejK"
                     /locus_tag="RH288_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HDV4029932.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELH
                     RVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGF
                     VLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELKSLSKELAGVSEVSFTEFAAEKGYELEESFPADR
                     STLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     N"
     gene            54769..54996
                     /locus_tag="RH288_000842"
     CDS             54769..54996
                     /locus_tag="RH288_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HDV4029933.1"
                     /translation="MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNL
                     INTSIAPAQRQAIANSFARALQSSINEDKAH"
     gene            55016..56776
                     /gene="pbgA"
                     /locus_tag="RH288_000843"
     CDS             55016..56776
                     /gene="pbgA"
                     /locus_tag="RH288_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HDV4029934.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWP
                     TTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKL
                     RSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITAL
                     NQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNR
                     WFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAG
                     RGIPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTP
                     ASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDE
                     KPQLSLLLQVLTDEKRFIAN"
     gene            56851..56927
                     /locus_tag="RH288_000844"
     tRNA            56851..56927
                     /locus_tag="RH288_000844"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56885..56887,aa:Pro,seq:ggg)
     gene            57137..58378
                     /locus_tag="RH288_000845"
     CDS             57137..58378
                     /locus_tag="RH288_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000101915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV4029935.1"
                     /translation="MARKTTPLTITEIKNARPGEKEYTLQDGGGLFLLVKPSGSKIWR
                     FTYYRPADKKRTIISLGSLNDVSLSDARERRNEYRSLIAKGTDPQDYERRKREAESSK
                     KGNTFEKVALDWYEMKKGQNLAYNTIKDIWRSLEKYVFPYIGNTPIDTLTARRFVEIL
                     TPIKARGNLETLKRVLQRINEVMDFAANSGLIDINTAANVRKAFPSPTKKHMPTIRPE
                     QLPQLMHDLSVASIERQTRLLIEWQLLTVARPAEAAAARWEEIDLDAETWTIPAGRMK
                     MRRDHVIPLCGQAMAVLETMKPISAHREHVFPSLKNPMLPMSSQTANAALRRMGYAGV
                     LVSHGLRAIFSTAANEEGFEPDVIEAALAHVDTNEVRRAYNRSNYLEKRVVLMRWWGE
                     FVEAAATGVTIASGKRGIRAV"
     gene            58495..58737
                     /locus_tag="RH288_000846"
     CDS             58495..58737
                     /locus_tag="RH288_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029936.1"
                     /translation="MFFNEKVSPACGEGLQLALMANREFWSTYDPEDKSTAPTKHEVV
                     SFLRSRGASKNLAESIDKVLRPTSLKCGGRPKKWKR"
     gene            58908..59114
                     /locus_tag="RH288_000847"
     CDS             58908..59114
                     /locus_tag="RH288_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HDV4029937.1"
                     /translation="METIRKILTRQEVKNILRIKADSSLQDMINAGKFPKGFKIGLRR
                     VGWYEDEVLAWLKEREEEARGTAA"
     gene            59134..60237
                     /locus_tag="RH288_000848"
     CDS             59134..60237
                     /locus_tag="RH288_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001439643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
                     /protein_id="HDV4029938.1"
                     /translation="MNITKSAPLPERPCEQLTYCAKNESVQWDYINRVAKRHNCRITG
                     KTKATRYGGPSTQATRYPQRMSIANNATFAAGGQCDQCAGLLVGYSCSLTLPCRDVFQ
                     VCDPIFVRLYSFKNFSRANAHGANLSCSCSLTAFLRCFFLDEDNFFNDLSVIVDTCNP
                     VRHSSPHHSAGDGYSCSLALRRWRRLISPCIDVMMNCDVLSPDSFTDSMAFTISCGTR
                     AFRACDFAFVVPVAISIPLVDWWGTVYTEKAQIKLLTWATPKTYSGPHLKIIKAHKCK
                     APQVSLPLAGLLTTNDSRSIEVAMLNHTTHPQGRDSHNLNKYIWRFIALSAAQPRVIT
                     IEATNEQEARQQSPDGCVMVFAARIRQEVRHVQ"
     gene            60227..60679
                     /locus_tag="RH288_000849"
     CDS             60227..60679
                     /locus_tag="RH288_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029939.1"
                     /translation="MCNNTRQDAAAEAIKTLMHALIDISVIADRAHKHATSETEYAGA
                     FVPHSLAVMQFSADMALNEAKAILITDCENGGVMRDDRFNALKQEFSGVPGDAADALS
                     SMPELIRADFFLLSTKEYKSTGLDVLNIAADYADFVTEVILRKATDGD"
     gene            60681..60914
                     /locus_tag="RH288_000850"
     CDS             60681..60914
                     /locus_tag="RH288_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029940.1"
                     /translation="MRDIYHETIDRAFLALSHSENMLEILRLWLETLGDNERDKQKSR
                     IVTALITLLEPVIMELQEIDLLHDRYKEQHTGE"
     gene            60920..61219
                     /locus_tag="RH288_000851"
     CDS             60920..61219
                     /locus_tag="RH288_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HDV4029941.1"
                     /translation="MKLKYPGLTASGKTRTKFMRGDIYRDQYGGTVMIKGVEERRVTY
                     RREGYEYDCVMPVYQFARDFSLVQTAPHNVPTSNARARANIQKLKTMINAFRGKK"
     gene            61216..63021
                     /locus_tag="RH288_000852"
     CDS             61216..63021
                     /locus_tag="RH288_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDV4029942.1"
                     /translation="MKLAPNLKKQPHDKMTEVIIFAGSDAWAHAKQWQEQDGRLAGDN
                     VPPVWLGDSQLDELADLKIIDDGRYCVRLYKAGHIKPSNINAIGQKLAVAGVRDANYY
                     PEGMHSQKRENWHEYLERERQNLSDGLVIQLPVKKKTEDSAAPLALNQMGASQRGEVL
                     LARYGGELAINADSDTVHHYNGVVWEPVQDKELQRAMAQIFIDAEISYSQNAIKSAVD
                     TMKLSLPVMGNTARNLIGFSNGVFDTRTGDFREHDKNDWLLIASELPFSPPAEGETLA
                     THAPNFWKWLRRSVAENDRKADRVLAALFMVLANRYDWQLFLEVTGPGGSGKSVMAEI
                     CTMLAGKANTVSASMKALEDARERALVVGFSLIIMPDMTRYAGDGAGIKAITGGDKVA
                     IDPKHKAPYSTRIQAVVLAVNNNAMSFSDRSGGISRRRVIFNFSEVVPENERDPMLAE
                     KIEGELAVVIRHLLTRFSDQDEAKRLLYEQQKSEEALVIKREGDSLVDFCGYLMSSVM
                     CDGLLVGNAEIIPFSPRRYLYHAYLAYMRAHGFGKPVTLTRFGKDMPGAMAEYGREYM
                     KRKTKHGLRSNVTLTEDSEDWMPSCASVTNDDGKN"
     gene            63308..63553
                     /locus_tag="RH288_000853"
     CDS             63308..63553
                     /locus_tag="RH288_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029943.1"
                     /translation="MTTKHAKKPQSHALDLTEHWLRVAIKIIDRNAGEGYAKAHPELI
                     SAFMTTAAANFATLTEREIAEAEQVTTINVKTGEVES"
     gene            63550..63972
                     /locus_tag="RH288_000854"
     CDS             63550..63972
                     /locus_tag="RH288_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001758993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDV4029944.1"
                     /translation="MTAQIAAYGRLVADPQLKTTSKGTQMAMASMAVPLPCSQADDGT
                     ATMWLSVLAFGRQADALAKHQKGELVSVAGNMQISQWTGQNGETRQGWQVIADSVISA
                     RTARPGGKKGQQGQATDALNRAKQQAGNDDPYGDNIPF"
BASE COUNT        15992 a        16554 c        15951 g        15655 t
ORIGIN      
        1 attttgacgc caccaaacaa ccgtgcggcc tattgataaa gagctaacac attgtcaaaa
       61 aacatcacta tggtttttta gagtttctcg atatcaattg cctgaatagc ccttgcaata
      121 tcaggggaat tattcaacac ccgaacatgc tgaaataatt ccgttgcttc atcgtattct
      181 ttacgcaaat aactcaacca ctgtttaatc cgcgcaacgt gatataaccc ggtatcgccc
      241 tgcttttcca gacgggtata tttttgcagc aaagcaacca cctccggcca cggcattcgc
      301 ggttcgttat attttaccac ccggctcagg ttgggaatat tgagcgcccc gcgaccaatc
      361 atcactgcgt cgcagccgct gatcgccatg cattgttgcg cgctctgcca gtcccagatt
      421 tcaccgttgg caatcaccgg aatattcagc cgctggcgaa tatcgccaat cgcctgccag
      481 tcaatatgct ccgcgcggta accctgctct ttcgtccgcc catgcaccac cagctccgta
      541 gcgccagcct gttgaaccgc atcggcgatt tcaaatttct tctcaccgct gtcccagccc
      601 agacgcactt tcacgctgac gggcaaatgc gccggtacag cttcacgcat cgcttttgca
      661 ccctggtaga tgagttcagg atctttgagt aacgtcgccc cgccgccgct accgttaacc
      721 gttttcgacg ggcagccgca attgagatcc acgccccagg aacctaactc caccgcacgg
      781 gcggcgttct ctgccagcca ttgtgggaac tgacctaaca actgcacgcg caccagcgta
      841 ccagatggtg tccggctggc gttttgtagc tcagggcaaa tgcgatgaaa gacttttacc
      901 ggcagcagtt gatccaccac gcggacaaac tcggtgatgc acagatcgta gtcgttaact
      961 tcggtcagca attcacgcac cagagagtca agcactccct ccatcggtgc cagtaacaca
     1021 cgcatatcat cacccgcaaa aaaatgaggc gctatgttag cgcctatggt cagcggatta
     1081 aaggtctgca aagagggatt gctgcaaact gcaatccctc tctatgcttg atgtatgcct
     1141 gagttcgctg cgcattgcgt aatgccgggg agcgaaaaaa taagcgctga tttcttaatg
     1201 tgatcggtag cacgttttac gaattaattg tatgatgaat ccatctcatc tggggtgttg
     1261 attatgagta agacactgaa cattatctgg caatatttac gcgctttcgt cctgatttat
     1321 gcctgcctgt atgcaggcat tttcattgct tccctgctac cggtaaccat tccgggcagc
     1381 atcatcggga tgctgatcct gtttgtcctg ctggccttgc aaattcttcc ggcaaaatgg
     1441 gtcaatccgg ggtgctacgt actgattcgc tatatggcgc tattgtttgt gccgattggc
     1501 gtaggcgtca tgcaatattt tgatttgctc cgcgcacagt ttggcccggt agtggtttcc
     1561 tgtgcagtca gtacgctggt ggtttttctg gtggtgagct ggagttcgca actggtacac
     1621 ggtgaacgta aagtcgtagg tcagaaagga tcagaagaat gatggcgaat atctggtggt
     1681 cattaccact gacattgatt gtcttttttg ccgcccgcaa actggcggca cggtataagt
     1741 ttcccttgct taacccgttg ctggtagcaa tggtggtgat cattcctttt ttaatgctga
     1801 ctggcatctc ttacgacagc tactttaaag gtagcgaagt gctaaacgat ctgctgcaac
     1861 cggcggtcgt cgcgctggcc tatcctttat atgagcagct acaccagatc cgcgcgcgct
     1921 ggaaatcgat catcaccatc tgttttatcg gcagcgtggt tgcgatggtg acggggactt
     1981 ccgtggcatt gttgatgggc gcttcaccgg aaatcgccgc gtcaatcctg ccgaaatcag
     2041 tcaccacgcc tattgcaatg gcggttggcg gcagtattgg cggtattccg gcaatcagcg
     2101 cagtttgcgt gattttcgtc ggcatcctcg gcgcggtatt tggccataca ttgcttaatg
     2161 cgatgcgtat tcgtaccaaa gctgcgcgcg gtctggcaat ggggactgcc tcgcacgccc
     2221 tcggtacggc gcgctgcgcc gagctggatt atcaggaagg tgcatttagt tcgctagcgc
     2281 tggtgttatg cgggataatt acttcgctga tcgcaccgtt ccttttcccg attattctgg
     2341 cagtaatggg ctaaaatttg cgatgcgtcg cgcatttttg atgtatgttt cacgcgttgc
     2401 ataattaatg agattcagat cacatataaa gccacaacgg gttcgtaaac tgttatccca
     2461 ttacatgatt atgaggcaac gccatgcatc cacgttttca aaccgctttt gcccaacttg
     2521 cggataactt gcaatctgca ctggaaccta ttctggcaga caagtacttc cccgctttgt
     2581 tgaccgggga gcaagtctca tcgctgaaga gcgcaacggg gctggacgaa gacgcgctgg
     2641 cattcgcact acttccgctg gcggcggcct gtgcgcgtac gccattgtcg aattttaatg
     2701 ttggcgcaat tgcgcgcggt gtgagcggaa cctggtattt cggtgccaat atggaattta
     2761 ttggtgcgac aatgcagcaa accgttcatg ccgaacaaag cgcgatcagc cacgcctggt
     2821 tgagtggtga aaaagcgctt gcagccatca ccgttaacta cacgccttgt ggtcactgcc
     2881 gtcagtttat gaatgaactg aacagcggtc tggatctgcg tattcatctg ccgggccgcg
     2941 aggcacacgc gctgcgtgac tatctgccag atgcctttgg gccgaaagat ctggagatta
     3001 aaacgctgct gatggacgaa caggatcacg gctatgcgct gacgggtgat gcgctttctc
     3061 aggcagcgat tgcggcggca aaccgttcgc acatgcctta cagtaagtcg ccaagcggtg
     3121 tcgcgctgga atgtaaagac ggtcgtattt tcagtggcag ctacgctgaa aacgccgcat
     3181 tcaacccgac tctgccaccg ttgcagggag cgttaattct gttgaatctc aagggttatg
     3241 attacccgga tatccagcgc gcggttctgg cagaaaaagc cgatgcgccg ttgattcagt
     3301 gggatgccac ctccgcaacg ctgaaagctc tcggctgtca cagtatcgac cgagtgcttc
     3361 tcgcttaagc ctggtgccgg atgcggcgtg aacgccttgt ccggcttgcc agccctctcc
     3421 tggtgtcgaa attcccggca aacagtttgc cgtttcttgc gcaaaaccag cgggtaaagt
     3481 agcctgatgg aaattttcct tagatcgagt ctcctgcatg ttaaagcgcg tgttcctcag
     3541 cctgttagtc ctgatcggct tgctgctgtt gactgtgctc ggcctcgatc gctggatgag
     3601 ctggaaaacc gcgccttata tctacgacga attgcaggat ctcccctacc gccaggtcgg
     3661 tgtggtgctc ggaacagcaa aatattatcg tactggcgta attaatcagt attatcgcta
     3721 ccgcattcaa ggagcgatta atgcctataa cagcggtaag gtaaattatc tattactgag
     3781 cggcgataac gcattgcaaa gttataatga gccgatgacc atgcgcaaag atttaatcgc
     3841 tgctggtgtc gacccatcag atattgttct cgattacgca ggctttcgta cgctggattc
     3901 catcgtgcgt acacgcaaag ttttcgatac taatgatttc attattatca cccaacgttt
     3961 ccactgtgag cgagcattat ttattgcgct gcatatgggg attcaggctc agtgttatgc
     4021 cgtaccgtca ccgaaagata tgctgtcagt acgtattcgt gaatttgccg cccgtttcgg
     4081 tgcgctggct gacctttata tttttaaacg tgaaccgcgt tttttagggc cgctggtccc
     4141 tattccggct atgcaccagg taccggaaga tgcgcagggg tatcccgccg tcacacccga
     4201 acagttactt gaattacaaa agaaacaagg aaagtagtta tggatgtaca gcagtttttt
     4261 gtcgttgccg tttttttcct tatcccgata ttttgtttcc gcgaagcatg gaaaggctgg
     4321 cgcgcaggcg cgattgataa acgggttaaa aatgcaccgg aaccggtgta tgtctggcga
     4381 gcaaaaaatc ccggactctt tttcgcttat atggtggcat atatcggctt cggaatttta
     4441 tctatcggca tgattgttta tcttattttc tatcgttaat attcccctct ccagttaatt
     4501 attgagaata attattactt cacctgataa gctgcggata tcacattcct aaccgcagct
     4561 atttgtgaat cttttcacag tttaaattcc cccgcacgct tagccttaat atcagtacat
     4621 tattatttac taaacgctcg ccttaattac ctatagcatt aaggaagatc acatgccgca
     4681 acaaaattat ctggatgaac tcactccggc ttttacgtct ttactggcga ttaaagaagc
     4741 ctctcgctgt ttattatgtc acgacgctcc ctgtagtcag gcttgcccgg cacagaccga
     4801 tccggggaaa tttattcgct caatctactt tcgtaatttt aaaggcgctg ccgagacaat
     4861 tcgcgaaaat aatgccctcg gtgccgtttg tgccagagtg tgcccgacgg agaaattatg
     4921 ccaaagcggt tgtacccgtg ccggtgttga tgctcccatt gatatcggcc gcttacagcg
     4981 ttttgttact gattttgaac aacaaaccgg aatggaaatt tatcagcccg gtactaaaac
     5041 gctcggcaaa gtcgcgatta ttggcgcagg tcctgccgga ttgcaggcca gtgtgacact
     5101 gacaaaccag ggttatgacg tcacgattta tgagaaagaa gcgcaccccg gtggctggtt
     5161 gcgtaacggt attccgcaat tccggttacc gcaatcagtg ctggatgcag agatcgcccg
     5221 tattgaaaaa atgggcgtga ccattaagtg caacaacgaa gtcggtaaca cactcaccct
     5281 tgagcagctg aaagcagaaa accgcgcggt actggtcacc gtggggttat caagcggttc
     5341 cgggctaccg ctgtttgagc atagtgacgt tgagattgcc gtcgacttct tgcaacgtgc
     5401 acgacaggcg caaggcgata tcagcattcc acaaagcgca ttaattatcg gcggcggtga
     5461 tgtcgcgatg gacgtagcca gcacgctgaa agttctcggc tgtcaggcgg taacttgcgt
     5521 agcgcgtgaa gagttagatg agtttccggc aagcgaaaaa gagtttacca gcgcccggga
     5581 gctgggcgtt tcgatcatcg atggattcac gccagtagcc gtggaaggca ataaagtcac
     5641 gtttaagcat gtacggttat cgggcgaact gacgatggcg gcagataaaa ttattctcgc
     5701 cgtcggtcag catgccagac tagatgcctt tgcggagtta gagccgcagc gtaacaccat
     5761 caaaacacaa aattaccaga cccgcgaccc gcaagtcttt gctgctggcg atattgttga
     5821 gggtgacaaa accgtggtct atgccgtgaa aaccgggaaa gaagccgccg aggcgattca
     5881 tcactattta gagggagctt gctcatgtta acgaaagatc tttcgattac tttttgcggc
     5941 gtgaagtttc ccaacccgtt ctgcctctct tcttcgccgg taggcaactg ctatgagatg
     6001 tgtgccaaag cctacgacac aggttggggc ggtgtggtgt ttaaaacgat cggctttttt
     6061 atcgccaacg aagtctcgcc gcgttttgat catctggtga aagaagatac cggttttatc
     6121 ggcttcaaaa atatggagca gattgctgaa catccgttgg aagagaatct ggccgccctg
     6181 cgtcggctga aggaagatta cccggacaaa gtattgatcg cttcgatcat gggggaaaat
     6241 gagcagcaat gggaggagct ggcgcgcctg gtgcaagaag ctggcgcgga tatgatcgag
     6301 tgtaacttct cctgtccgca aatgacttct catgcgatgg gtagcgatgt cgggcaaagc
     6361 ccggagctgg tagaaaaata ttgtcgggca gtgaaacggg gttccacgct gccaatgctg
     6421 gcgaagatga cgccgaatat cggtgatatg tgcgaagtgg cgctggcggc gaagcgcggc
     6481 ggcgcagatg gcattgcggc gattaacacc gttaaatcca tcaccaatat cgatcttaat
     6541 cagaaaatcg gtatgccgat cgttaacgga aaatcgagta tttccggata ttccggtaaa
     6601 gcggtaaaac cgatcgccct gcgcttcatt cagcaaatgc gcacccatcc agaactgcgc
     6661 gatttcccaa tcagcggtat cggcggcatt gaaacctggg aggatgcggc tgagttttta
     6721 ttgctcggcg cagcaacgtt acaggtgacc accggcatca tgcagtacgg gtatcggata
     6781 gtggaagata tggcaagcgg gttgtcgcat tatctcgccg atcagggatt tgattcgctg
     6841 caggagatgg taggtctggc gaataacaat attgtcccgg cggaagattt agaccgcagt
     6901 tatattgtct atccccgtat caatcttgat aaatgtgttg gctgtggacg ctgttatatt
     6961 tcctgttacg acggcggtca ccaggcgatg gaatggagcg agaaaacccg cacaccgcat
     7021 tgtaataccg agaaatgtgt gggttgtctg ctttgtggtc acgtctgccc ggtgggttgt
     7081 attgagctcg gggaagtgaa gtttaagaaa ggcgagaaag aacacccggt aacgttgtaa
     7141 aaccagagac gcatccggca tttggttcct gtcgccggat gcggcttgaa cgccttatcc
     7201 ggcctacaaa accatacaaa tcagtatgtt gagcttattg taggccggat aaaacgcgcc
     7261 agcgttgcat ccggcatttg gctcctgttg ccggatgcgg cgtgaacgcc ttatccggcc
     7321 tacaaaacca cacagatcat gatgttatgt gcgtttatga ccgaatgcgg accacattca
     7381 catcatttct tacgcgcgta tttcagtgaa tccagcgcta cggcgaagat aataatcgcc
     7441 cctttgatga tgtactgcca gtatgggttt acgccgatat acgtcaggcc atagttgatg
     7501 acggtaaaaa taattacccc ggtcaccacg ccaatcaccg tccccacacc gccgctgaac
     7561 gatacaccgc ctaccacgca cgccgcgata gcatccagct catacataaa gccgaggttg
     7621 ttggtggcag agccgatacg tccggcttct aacatcccgc caaaggcata gaacacgcca
     7681 gacaacgcgt agatcatcag caggttcagg ccgacgttga caccagatac ttttgccgct
     7741 tccgggttac cgccaatggc aaaaatgttc ttaccgaagc gggttttgtt ccacaacacc
     7801 cagacgaacg ccaccgcaat caacgcgtag aaggtgatgt aagagagacg gaaactcccc
     7861 agcgcgacaa agccctgagc aaaggtagag aagccactgt caaaaccaga aattggcgac
     7921 gccccgacaa agtcgtaata gagcgagttg atgccataga cgatgatcat cgtgccgagc
     7981 gtggtaatga acggcgtcac gttgagataa gcgataatca gaccgttgat caaaccgatc
     8041 accgcaccaa tggcacagac aatcagaata accagcgcaa tcggcatcgt cgccatttcc
     8101 gggaacactt tgttggcgtt atccatggac tgcaataatg tcgcagccac cactgccgcc
     8161 agccctacct gacgaccagc agaaagatcg gtcccctggg tgacaattaa ccctgccaca
     8221 ccgagcgcga taataatacg caccgatgac tgggtgagaa tattacttaa gttcaacaga
     8281 cttaaaaatg ttgggtcctg gaaaataata atcgccagca aaactaaaag aacgacgtaa
     8341 ataccgccct ctttcaggta agtaagaaaa cttttcttat ttaacgcact catgggaagc
     8401 ccctaatctt aaaggtgcaa agacgcaaga cgcagaattt cgttttgcgt tgttgttttt
     8461 gtatcgacaa ttccggaaac gagaccattg ctcatgacca gaatacggtc tgttatccct
     8521 aacaactcag gcatttcaga ggagataata ataatcccct tgcctttctt cgccagttcg
     8581 gcaattaact gataaatttc aaacttcgcc ccgacatcaa taccgcgcgt cggttcatcg
     8641 agcattaata tttctggttg cgttagtagc cagcgaccaa taatcacctt ttgctgatta
     8701 ccaccggaga gcgaaccaat ttgcgtccga tgacccggcg tttttacccg catcgaatca
     8761 atcacccact gggtatcgct tttcatccgc gagttatcca gtaaaccaac tttatttttg
     8821 tagttgcgaa tattggaaat taacgagtta aaaccaatat ccagataggc ataaattccc
     8881 gttgagcggc gctcctcagt taccagtgca aatccatggt ttatggcttc gttggcatta
     8941 tggttattga tctgtttgcc gtgcaacgtt atggtgccag ccgatttctc gcgaatacca
     9001 aataacgtct caacaatatc ggtacgtttc gcccccacca gaccggcaat accgaggatc
     9061 tcccctttat gcagatcaaa cgagacatcg cgaatcgacg gctggcgcag tgacgtcagg
     9121 ttacgtacct cgaggatgac ttcgcccggt ttgttttctt tgtcagggaa acgctggtta
     9181 agagaacgcc caaccatcat ggcgatgatc ttgtccatcg tcagtcctgc cagcggttcg
     9241 gtggcgatcc actgaccgtc gcgcaatacg gtaacttcat cacataactg gaagatttct
     9301 tccattttat gcgagatata aacaataccg cagccgcgct cttttaattt acgaataata
     9361 gtgaacagat gattgacctc tttttcggtt aacgaagaag tcggttcatc cataatcaca
     9421 attttcgcgt tataggaaaa cgctttggcg atttcgatca tctgcatttg cgaaacggat
     9481 aatgtgccga cgcgcgcacg cggatcgata tcaatatcca gttcgtcaaa aatcgctttg
     9541 gtttcgcggt acattttgtc ctgatcgaca aacatgcctt tggtgggata tcgccccagc
     9601 cacatgttat ccatcaccga acgttgtaat accaggttta actcctggtg taccatcgaa
     9661 ataccatttt ccagggcttc ttttgcagaa tggaaatcga tctctttacc ctggaataaa
     9721 atggtgccgg agtctttttg ataaatacca aacaggcatt ttaataatgt cgattttcct
     9781 gcaccgtttt cccccattaa tgcatggata gaatgtggcc ggacttttaa attaacgtta
     9841 tcaagtgcct taacaccagg aaaggacttg ttgataccgc tcatttccaa caagtattcc
     9901 ccggaggacg gagtcgttga gctgaccata taattttacc ttgttggcca tacaataagg
     9961 gcgcagtaat agactgcgcc caatcagtct tatttcttgc tgaattcagc caggttgtct
    10021 ttatctacgc caacataagg tacgcggacc actttgttgt cgattttcca gttggtgcca
    10081 tcagccgcac ctttaccatc ggccaggttt ttcgccagat caaaggtcgc tttcgcctgg
    10141 ttgttagcat cgttcagtac ggtgcccgcc agtgcaccgg atttcaccag cgccagcgct
    10201 tctggcagcg catcgacgcc aaacaccgga atgctggact tgttgtgtgc tttcagcgct
    10261 tcaaccgcgc ccattgccat cgcatcgttg ttggcgataa ccacttcgat tttgttggcg
    10321 ttcgggccag acagccaggc gtccatctta tctttcgcct gagcggtgtc ccacattgcg
    10381 gtatctaact gtaactgttc agttttgatg cctttatcgt tcaattcttt aatcacgtaa
    10441 gtggtacgtg cttctgcatc cggatggccc ggttcacctt tcagcagtac gaactgaatc
    10501 tgaccgtctt tgttcagatc ccaaccctga ttcgccgccc agtgtttagc aatcaaatcg
    10561 ccttgaataa tgccggactc tttggagtca gtgccaacgt agtaggcttt gtcgtagcta
    10621 tccagcgcct tacgagacgg ttctttgttg aagaaaacca ccggcacgtt ttgcccacgc
    10681 gctttctcaa tcaccgtacc cgcagctgcc gggtcaacca ggttgattgc cagtgccttc
    10741 acccctttcg ccagcaatac gtcgatctga tcgttctgct tggactggtc attctgagaa
    10801 tcattcatca gcagctgaac atctggcgcg gctttcgcat cttgctcaat agccttgcgc
    10861 actacagaca taaagttatc gtcgtactta tagattgtta caccaatgcg agtatcagca
    10921 gcgtgtgcag cggcaccgaa taacatgctg gccatcacag cagacagggt taacaccttc
    10981 ttattcatgg tatctccggt ttttcttatg cagggtagtg cttgagataa atgctcggcg
    11041 gggcagtaga gttaatgaag tgttactgaa cgccgaagct cactttttaa aattcgttct
    11101 tccatgcccg gtaacgctcc agaaaacggc tttaattgtt gttatgacgc tgttacctcg
    11161 gcaaaagtga ttattcactg ttacatacgg gttacaacgt taaaacggtg caatcatagc
    11221 tatcacattg ttaagatact gtgaaatcac tcacagattg aaagcggtta catcgcctga
    11281 tttgttgagt tagtgatcgc cgccgcattc tggcgtgttg cgacagaatg gcgacgcact
    11341 aacgtcggca taaaacagtg gctggcacga ggatcaatat tgcctgctgc cccctgcaag
    11401 gccagttcgg tggctaattt cgccattgaa gcaatgggat aacgcacggt cgttaattgc
    11461 gggtcggtgt aacgggcgat gggaatatca tcgaaaccga tgattgagag atgtaacgga
    11521 atcgcaatgc cattatcttt taatgctgtc agtgcgccag cggccatatt gtcgttataa
    11581 gcaaatacag cggtaagttg tagattgcgc cccagcagtt caaccatcgc cgcctcaccg
    11641 cccggcatgt ccggcgtacc agcgccaatc cagctttccg gcggaataat atcctgctct
    11701 ttcaacgcac tcatccagcc tgctttacgc atggcgtcat cttcaatgcc gtggctggaa
    11761 gaaagataac caatacgttg atgaccgtta ttcagcaaca tgcgcgtcgc cattcgggca
    11821 ccgctgagat tatccaggca aacgcaacga tgggcgtacc ccggcacaac gcggttgatt
    11881 aacaccatac cgggaatgtt atccataaat tgcgccagtt catcgtcact caatgctttt
    11941 gagtgaacaa tcaacgcatt acaacgctgg cgaattaaca cctcaatggc gtgacgctct
    12001 ttttccgctt catgatagct attgccgatt agcacgtatt tctgatgctg ctgagcgacc
    12061 agatccaccg cttttaccag cgcgccgaaa aacgcatcag aaacgtccat caccaccacg
    12121 ccaatggtgt cgctaacctg agttgccagc gcctgggcat tggcgtttgg ccgataatcc
    12181 agctcactca cggctttcat tactgcttca cgcgtgtcgg cactgaccag cgtgctgtta
    12241 ttgagcaccc gggaaaccgt tgccacagag acgccagcct gacgcgctac atcacgaatg
    12301 gtgatcatat tcactacctg ttatgagatt gcagtaaatg actgcttgct ggcggctatt
    12361 ttgtcagcac tgaatacagg acttcgtgaa tcgagtcaca gcaatggaaa cggttacagc
    12421 cgttttgtta acgaatgtga tccagatcgt tatcttgatg ttttagatat tgccggtccg
    12481 gcagcacgca aagttaactg acgccagagc cattccaccg gcccctggcg gaagtaacgc
    12541 agccagataa cagagaagag gatattcgcc agccataccg gaataacaaa cgccagcagc
    12601 tccaggcggt caaaatgcat aaacaaaccg aggtggtaaa aaagcgtggt acaaatcagc
    12661 gtttgcaata gatagttggt cagcgccatc cgtccgacgc aggcgatcgc aagcaccagc
    12721 ttaaagcggc tcaattgcgg ccagaagcca taaaacagcg acgcatagcc aatcgcctga
    12781 aacggcgcac tcagttcccg cggcatttga agtaagaagg cacaccagcg atacgcccag
    12841 tccagctgcc attgcagggc gatggcagga aggttaatgg tcaccccaat cgccaccagc
    12901 acaaaaccag tacgacgata gtgacgtaag ctgaactgcc ctttcagcca gccgctgcgc
    12961 atcagcgccg caccaatgag catcatccct gccagttgcc agccatactg tgcgcccagt
    13021 gccagtaaac tgttgccaac accatcggca cgattactga tcgcttcaac gccgccgtga
    13081 agcttccagt atttttcata caaaatagcc gatgcatccg gcgtccaggc gcggctggtc
    13141 tggctgtcgg aaatcagccc caataacagc aaaacgccaa gccccaccag ataaagcatg
    13201 acgcctgtat taaacaggct ttttaccgat ggcgcatcgc gcaccagccg ccagcagatt
    13261 aagcccacca gcccgtaagc cagcaaaata tcgccgtccc agaacaataa accgtgaata
    13321 aagcccaaca agactaacag cgttaaccgc gactggatcc agcgtctgcc acggggcagc
    13381 aacatttgca ggcccgcacc aaacagtagc gcaaaaagcg tgaggaattt cacctggccg
    13441 atgagatcaa gaaatgccca agtccatgca tcccgcggcg taatagcacc gtaccaggcg
    13501 ggattgagat aagccgcctt tggtagccca aaggcgctga tgtttaatag caggatcccc
    13561 agaatggcga cgccgcgaac aaaatcgagc gtgacgttgc gctccatggt tcctgccttt
    13621 taatcagttg tgatgacgca cagcgcgcag aaactcgtgg cgcgtattct gactggattt
    13681 gaacaatcca ccaagagagg tcgttgtcgt ggcactggtt gcatcgcgga tgccacgcgc
    13741 cttcacgcag taatgcaccg cgtcgatcga gacagccacg ttattggtgc ccagcagcgt
    13801 ttgtagcgca ataagaattt gctgcgtcag acgttcctgc acctgcggac gctgggcaaa
    13861 gaactgcaca atgcggttaa tttttgacag accgatcacc gaatctttcg ggatataggc
    13921 caccgtcgct ttgccatcga tggtaacaaa atggtgttca caggtgctgg tcagagtgat
    13981 atcgcgcacg gtgaccattt catcgacctt cattttgttt tcaatgaggg tgattttcgg
    14041 gaaattggcg taatccagac cggagaaaat ttcatcgaca tacattttag cgatgcgatg
    14101 cggcgtttcc atcaaactgt catcagccag gtcgagattc agcagctgca tgatttcggt
    14161 catatgacca gcaataaggc ttttgcgcgt ttcgttatcc atttcatgca cgggcgggcg
    14221 cagcggtgtt tccagtcctc gcgcaactaa cgcttcatga accagggccg cttctttact
    14281 gagtgatggc atttatgatt tctcctgcag gtgtgacgcc tccgccctgc gtgggggcaa
    14341 agttattaag ctgatttaca gcctgattat tgtgcgtgag gcggcgcaca taatccagta
    14401 ttcacagcga taattattgt aattgccgct gcctttcatc agcagatgtt aaaacatcgt
    14461 tatgcaaata cggaagtgaa agttactcac agcacattga ataaacggta tgatgaagaa
    14521 attgcaaaca acacaacaag gagccacgca tggaaatgct cgaagagcac cgctgttttg
    14581 aaggctggca gcaacgctgg cgacacgact ccagtacctt aaactgcccg atgacgttca
    14641 gtatctttct ccctccacct cgtgatcaca ctccgccacc agtgctgtac tggctttccg
    14701 gattaacctg caatgacgag aacttcacca ccaaggcggg tgcccagcgg gtagcggcgg
    14761 aactggggat tgtactggtg atgccagaca ccagcccgcg cggcgaaaag gttgccaacg
    14821 acgatggcta cgatttaggc cagggcgcag gcttttatct taatgccacg caaccgccgt
    14881 gggcgacgca ttaccggatg tatgattatc tgcgcgatga attaccggcg ctggttcagt
    14941 cgcaatttaa tgtcagcgac cgctgcgcca ttagcggtca ctcaatgggt ggtcacggtg
    15001 cgctgattat ggcgctgaaa aatccgggta aatacaccag cgtttcggcc tttgcgccaa
    15061 ttgtgaatcc gtgcagcgtc ccgtggggaa tcaaagcgtt tagcagctat ttaggtgagg
    15121 acaaaaatgc atggctggaa tgggacagtt gcgcactgat gtatgccagt aacgcgcagg
    15181 atgcgatccc gacgcttatc gatcagggcg ataatgatca gtttcttgcc gaccagttgc
    15241 aacctgcggt actggcagaa gccgcgcgcc agaaagcgtg gccgatgacg ctgcgtattc
    15301 agccgggata tgatcacagt tactacttca tcgcctcttt tatagaggat cacctgcgct
    15361 tccatgcgca gtatttactg aagtgaaagt ccgcccggtt cgccgggcat cttctcatca
    15421 gaagcgataa tccactgcca taaagtaacg acgtccgtct tcgttatagc tgtagtcgtc
    15481 acgactgaga tccttgtcgc caaggttcag cacgcctgcg cgcagtttga cgtctttagt
    15541 cacctgccag gccgcgccgg tattccagat ggtataaccg cccggtgttt tagccgtcgc
    15601 gctgtcggcg cgtttctgcc cggtatagtg cccagaaaca tagaatgacc agtcttccag
    15661 cgccagcggt ttccagtcca gcgtaccgtt agcagtatgg aacggcagat cggatagcgg
    15721 tttgttttcg ccgttgctga catcacgacc atcgttgtag gtgtagttga tcgacagttt
    15781 ccattcatcg ttgaacggaa ttttcagttc ggtttccacg ccctgaatac gagctttgtt
    15841 aacgttgtag tagctaaata ccggtatgcg ccgtccgtta gcgcccgtct caaaaccaac
    15901 aaagttttgg tagcccggtg cagcgttgac gtcagacgta cggctgatgc tgatacgatc
    15961 tttcacatcg ttacggaaaa cggtaacgct ggattcaacc ccttccagcc agccttcttc
    16021 acccatgtag taaagcccca gctcccaact ttcgctggtt tctggtttca gatccgggct
    16081 acccacaatc ttacatgcgc cacggcagga attgctcgtc cagtcagggc taagttgcaa
    16141 cagagaaggt gctttaaatg ccgtcgccca gccccctttc accgttacgg tgtcggtggc
    16201 gttataaacc aggtaggcac gcggactcca gtgttcaccg taggtttcgt gatcgtccat
    16261 acgcacgccg gtcgtcagcg ccagcggctc gaagatccgc cattcatctt ccacaaacag
    16321 cgcgtactgg ctggcagacg ttttggagct ggttcccccg gtcaggttca ccgcatcgct
    16381 aagtttgtcg tgacgccatt caccgccaac cgtgagaaac tgattaatcg ccgtcagcgg
    16441 caacgtgtat ttgccgtcga ccgtattgct ttcggaagtt atcgggctgc tgttgccagg
    16501 gtttttgttc tcgactttct caccgtagta tttcagttcg ctggtgccgt aatcccaacg
    16561 cccattatgg ctgacggagt agttctggcg ttccaggcgg tttttgtcca gcgagtcgga
    16621 atcacgatcc tgacggtcga aaccgtatcc ggcagtaaaa tcgtgatttt gattcggtgt
    16681 ccaggcaaat tcgacattgc cgtcgcggct ggagaatcct tcaatacgcg gcgtttctcc
    16741 ggtatcggtg gtcgttgagt tttgcgggtc atccttttca cgttttgcca ggctgccgta
    16801 agctttcatt cccagcacac catcaattaa tggtccactg gtaaagaact gaccgttata
    16861 ggtgtcaccg cgatcgcgat gttcctgaat ggtggtatcg acggtaacgg tacccgacca
    16921 tttctgaccg atttttttgg tgatgatatt cactacaccg ccgagcgcat cggaaccgta
    16981 cagcgacgac atcgggccac ggaccacttc aatacgttcg atggaatcga ccgggatcca
    17041 gttcagatcg aaatcattgt ggcggaagac ggcattgcgg gagttcacgc gtttaccgtc
    17101 gacgagaatc agggtatagc tgctgtccag accacgaata ctaacgccct tacggttatc
    17161 cccttcgttc gtcagttgta cgccaggcac ttctttgagg acatccttca gattctgtac
    17221 cggttttcgc tgcaggtctt cctgggtaat gacgctgata ctggcaggtg catctttaag
    17281 attttgttcc acggaagatg cagtgacaac catcgtttcg ccatcatcat cgaccgctaa
    17341 cacaggccat gcacaagaaa tagcggacaa acacagcccg acccgtacga aagggttcaa
    17401 cctaaacatt ccatatctcc atgaggtaac tacgaaaata aaatgggtta tcgctcacat
    17461 cttcttcacg tccccttgcg tacggcagca tcgcggtgga cttatttttt atgcaggtga
    17521 tcatcccaga aagccggaac agcctctgat ttgtcagcct tttttgattg cggcgtaacg
    17581 ataatgcaaa cgataacaat tatcaatcca aatgttaaat tttatatccg catgatttgt
    17641 cagggaaatg gaattgaaaa agccctctcg gttgagaggg cttagcaagg aagggaggaa
    17701 acttatttct tatcgttctg cgggaacttc atttcgctgt agcgtacgaa gtgagttcct
    17761 ttaatcagct tgtagccgaa ccaaataatc aggaacagcg ggataccaat atacgttgcc
    17821 gctacgccgc cccagtcaat agtatctttc aggaacgctt cgtagttctg gcccaaagtg
    17881 ataatcagac acagaatgaa tgcgaagatc ggccccagtg ggaagaaacc tgaacggtac
    17941 ggcagatcgt taatgtcgtg tccctgcaat acgtaaccgc gacggaagcg atagtggcta
    18001 atggcaatcc ccagccaggc gataaaaccc gtcatcccgg aggtgttcag cagccacagg
    18061 tataccgtct ggttgccaaa catggaggtc aggaagcaca gaccggcaat caccgtcgtc
    18121 gcatacagcg cattacgcgg cacgccacca cgcgacagtt tagcgaaaat gcgcggcgct
    18181 ttaccgtcac acgccagggt gtacagcata cgagtagacg catacatacc ggagttaccc
    18241 gctgacagca ccgccgtcag aataactgcg ttcatcaccg ccgccgcaga gagcagaccc
    18301 gcgtgctgga acaccagggt gaacggacta acgctgatgt ctttaacatc gttacgcagc
    18361 aggctcggat cggtgtacgg aataatcagg ctgataatca ggatcgcgaa cacatagaac
    18421 aacaggattc gccagaacac ctgacgtacc gcgcgtggaa tgtttttcgc cggatcttcg
    18481 gactcgcctg cagcaatacc gatcagctcg gttccctgga aagagaagcc gacaatcata
    18541 gctacgccga tcatcgccgc aaaaccacca gcaaacggcg cttcgccgat tgtccagttg
    18601 ctccagcccg caggctgcgc gcctttgaag ataccgataa tcatcagcac gccaacgatg
    18661 ataaagacaa taactgtcgt gactttgatc agtgagaacc agtattccgc ttcaccaaag
    18721 ccacgaactg agatgtagtt cagcaggaag ataacgccga ggaacaacgc actccagatc
    18781 cagcccggtg tatccgggaa ccaccagctc atgaccagct gagctgcaac caggtcaacg
    18841 gcgatagtca ccgcccagtt gtaccagtag ttccagccca gcgcgaagcc aaagccttct
    18901 tcaacatagt tctgaccgta agtggcaaac gaaccggaaa ccggcatata tgcagccagt
    18961 tcaccgagac tggtcatcag gaagtaaacc atcaggccaa tcagcatata cgagagcaat
    19021 gccccgcccg gacctgcctg agaaatcgtt gcgccagagg caacaaaaag acctgtaccg
    19081 atggaaccgc caatggcaat catcgtcagg tgacgcgcct ttaattcacg gcgtaagccc
    19141 ggcgcttctg tggttttagt ttcggaaacc atacaaaaat gctatccatc ttaaaaatga
    19201 ggcgcgattg tagcagacga ttggcaatcc ttccggcaga aatacacggt tataagacac
    19261 cttcatgatc gcccagggat tataagtaaa gcagccaatc tcttttctgg cgaatgcatg
    19321 ctgagggcgc tgcgtcacga aatcgacaca gcaccagcat gttcttgtac agcaacttaa
    19381 cgcggtacat tcgcgggatc gcaatagtcc agaaagcgcc gtagcgcgtt ggaaaggtgt
    19441 ttttgccgat gatgtatacg ccacaacgta cgcatcaggc gcggcagagg gaccgcaact
    19501 tcacttaatg tgcctgcctg caattgatct tcaatcaccc gtcgcgacag gcaactaatt
    19561 cccaacccat gacgcaccgc atgtttgatt gcctcggagt tacctaattc catcgccatc
    19621 tcaaacttcg gtaaatgtga cagcaataga taatcgacaa tctcccgcgt gccggaaccg
    19681 cgttcacgca ggatccacgg cgcagcggcc agctgctcta aggtgaccgg accacgggcc
    19741 aacggcgaag tcggcgcggc gaaaaccacc agctcgtctt ccagccacgg ttcagaaata
    19801 atttcagtgc tgtggcacgg tccttcaata aaaccaatat caacgcggaa atccagcacc
    19861 gcttgcatca cgtcctggct gttcccaacg ctaagttcaa tcggcaactg cggataatca
    19921 tggcgataac gagcgataac tgcaggcaga atgtagttac cgatggtact actggcatag
    19981 atacgaatcg cgccgttgtc ttcgcgaaac agttgttcga tttcaaccgc ctgttcaagc
    20041 aatgccaacg cacgcggata gagcagccgc ccgtgttcat taacaaccag tcttttcccc
    20101 acgcgatcaa acagttgcac gccaagctgc ccttccaggt cggtcaaggc tgcgctcact
    20161 gctgattgcg acaacgccag catcaccgac gcctgggtgg ttgatccact tttcaatact
    20221 tctgcaaaaa cttccaactg ccggagggtg atgtgcatag tcgcttacca cttataaaga
    20281 ttaattataa atatataatc aattttattt ttaaaccagt tagtcgtaac cttatgcccg
    20341 gttaaaggag agggttatga cgaatatcac cttacagaaa caacatcgta cactgtggca
    20401 ttttattccg gggttagccc tgagtgcagt tatcaccggg gtcgccctgt ggggtggttc
    20461 cattcccgcg gttgcgggtg ccgggtttag tgccctcacc ctcgcaatct tgttggggat
    20521 ggttttaggc aacaccatct atccgcacat ctggaaaagc tgtgacggtg gtgtgctgtt
    20581 tgccaagcaa tatttattac gtctgggtat cattctttat ggcttccgtc tgacgttctc
    20641 gcaaattgcc gatgtcggta tcagtgggat catcattgac gtgttgacgc tgtccagtac
    20701 cttcctgctg gcttgcttcc tggggcagaa agtgtttggt ctggataagc acaccagctg
    20761 gttgatcggt gccggtagca gtatctgtgg tgctgccgcg gtactggcga ctgagccggt
    20821 agtgaaagcg gaagccagta aagtaaccgt ggctgttgca accgttgtta tcttcgggac
    20881 cgtcgcgatt ttcctctacc cggcgatata tccgctgatg tctcaatggt ttagtccgga
    20941 aactttcggt atctacattg gttctactgt gcacgaagtg gcgcaggtgg tggcggcagg
    21001 tcatgccatc agcccggatg cggaaaacgc agcagttatt tccaaaatgc tgcgcgtgat
    21061 gatgctggct ccgttcctca tcctgctggc ggcgcgtgtt aaacagctgt ctggggcgaa
    21121 cagcggcgag aaaagcaaaa tcactattcc gtggtttgcc atcttgttca tcgtagttgc
    21181 catctttaac tcgttccacc tgttaccgca gagcgtggtg aacatgctgg taacgctgga
    21241 taccttcctg ctggcaatgg cgatggcggc gctgggtctg accactcacg tcagcgcgct
    21301 gaaaaaagct ggggcgaaac ctctgctgat ggcactggta ctgtttgcct ggctgattgt
    21361 tggtggtggt gcgattaact atgtgattca aagcgtcatc gcataaacca ctacatcttg
    21421 ctcctgttaa cccgctatca ttaccgtttt cctccagcgg gtttaacagg agtcctcgca
    21481 tgaaatacat tggagcgcac gttagtgctg ctggcggtct ggcaaatgcc gcaattcgcg
    21541 ccgccgaaat cgacgcaacc gcgtttgcct tgttcaccaa aaaccaacgt cagtggcgtg
    21601 ccgcaccgct cacgacgcaa accatcgatg aattcaaagc cgcctgtgaa aaatatcact
    21661 acacatcggc gcaaattctt ccccacgaca gttatctgat taacctcgga catccggtca
    21721 ctgaagctct ggaaaaatcg cgcgatgcct ttatagatga aatgcagcgt tgcgaacagc
    21781 tggggctttc tttgctcaac ttccaccctg gcagccatct gatgcagatt tcagaagagg
    21841 attgccttgc gcgtattgcc gaatccatca acattgcgct ggataaaact caaggtgtga
    21901 cagcggtgat agaaaacacc gccggtcagg gcagtaactt agggtttaaa ttcgaacatc
    21961 tcgcggcgat tatcgacggc gtggaagata aatcccgcgt cggcgtctgc attgatacct
    22021 gccatgcttt cgctgccggg tatgatttgc gtactccagc cgaatgcgag aaaacattcg
    22081 cggattttgc ccgtactgtc ggctttaagt atctgcgcgg gatgcacctt aacgatgcga
    22141 aaagcacctt tggcagccgc gttgaccgcc atcatagcct cggtgaaggc aatatcggtc
    22201 atgatgcgtt ccgctggatc atgcaggacg accgtttcga cggcattccg ctgatcctcg
    22261 aaaccatcaa cccggatatc tgggcagaag agatcgcctg gctgaaagcg caacaaactg
    22321 aaaaagcggt agcctgaaga tgaataaccg ggaaaaggag atccttgcaa ttttacggcg
    22381 taacccgctg attcagcaga acgaaattgc ggacatgctg caaatcagcc gttcgcgcgt
    22441 tgcggcgcat attatggatt taatgcgcaa aggccggatt aaaggcaaag gttacattct
    22501 caccgagcag gaatactgcg tagtggtggg gacaatcaat atggatattc gcgggatggc
    22561 ggatatccgt tacccgcaat cggcttctca tcccggtaca attcattgct cagcgggcgg
    22621 cgtgggacgc aacatcgccc acaatctggc gctgttaggc cgtgacgtcc atttgctttc
    22681 agtgattggc gatgactttt atggcgaaat gctcctggaa gaaacgcgcc gtgccggcgt
    22741 gaatgtctcc ggctgcgttc gtttgcatgg tcaaagcaca tcgacgtatc tggcaattgc
    22801 caatcgagac gatcaaaccg tgctggcgat taacgatacc catctgctgg aacagttgac
    22861 accgcaacta ctgaacgggt cgcgcgattt acttcgtcat gcgggcgtgg tactggctga
    22921 ttgcaacctg acagccgagg cgctggaatg ggtctttacc ctcgctgatg aaatcccggt
    22981 gtttgtcgat accgtttcag aattcaaagc gggcaaaatc aaacactggc tggcgcatat
    23041 tcacaccctg aaacccactt taccggagct ggaaatttta tggggacagg cgatcaccag
    23101 cgatgctgac cgtaataccg cagtgaatgc attgcatcag caaggtgttc agcaactgtt
    23161 tgtttatttg cccgatgagt cagtttattg cagcgaaaag gatggagaac aatttttgct
    23221 gaccgcgcca gcgcatacga cagtagacag ttttggtgct gacgatggtt ttatggcggg
    23281 cctggtatat agctttcttg aaggatacag tttccgcgac agcgcccgtt ttgcggtagc
    23341 ctgcgcggca atttcgcgcg ccagcggcag cttaaacaac cctaccctgt ctgccgataa
    23401 cgcgctttca ttagtgccaa tggtgtaaca atgttgccgg atgcgacgct taacgcgtct
    23461 tatccggcct acaaatcagg caatttcagc aagtaaatgt aggcctgata agcttgcgca
    23521 tcaggcaatg acactcaagc taaaccaata aagaacccgg caatggtcgc actcatcaag
    23581 ttggaaagcg tcgccgccgc cagcgcccgt aaaccaagct gggcgatttc cggcgcacgg
    23641 tgtggcgcaa ccgcagaaaa cgcccccacc accaccccga tagaaccaaa gttagcgaaa
    23701 ccgcacaacg cgaaggaaat aatcgccaca gttttagcat cgagagtgcc agccgtttgc
    23761 agatagggtg agaaattgag ataagcgaca aattcattta ttgccagttt ctgtccaatc
    23821 aaactcccgg caagattcgc atcactccag tccacaccca tcacccacgc cagtggagcc
    23881 agcaggtaac ctaaaatgga ctccagcgag gcatgttcaa aaccaaacca gccaccaacg
    23941 ccgccgataa taccgttaat caacgcaatt attgcaacaa atgccatcac cactgttgcc
    24001 acacctgcgg cgattttcag cccggtcatt gcccctgtcg cagcggcttc aataatgctt
    24061 tttggcggtg tttcggtgaa agagaggtta ttaaaggaaa cctgcgaaga ttccgttgcc
    24121 gggcttaaca ggcgggcaaa caagatcccg ccagggatcg ccattaatga tgccgccagc
    24181 agatattcca caggcacgcc cagtgcggcg taaccaatca ttgtcgaacc agcaatcgag
    24241 gccatgccac tacaaatcgc tgtaaataat tcattgcgat tcagacgatc gataaagggt
    24301 ttgacgattg ccggaatttc gttttgcccg aggaaaatgg tggtgaccgc gacgaatgac
    24361 tcgatcttgc tgatatttaa tgctttctgg aagataccgc cgagaattcg aattaaaatc
    24421 cccatcacac cgatgtagta gagaatactc accagcgcgg tgacgaagat aattgccggt
    24481 aacaccctga aaccaaagat aaatcctgca ccatcaaata aggtatccat tttcggtccg
    24541 accagagaac cgaagataaa tgcgctaccc gcgtcgctgt acgccatcac tttatgcacg
    24601 ccaaaagcga ctttttcagc gacccaacgc cctggcggta accaaagcat aatgccgcca
    24661 atcacgacct gtaacactaa cgccgcgcca acggtacgca ggctgatctt cttcttgttt
    24721 actgacagta aaaacgcaat cgtcagcaat accaccattc ccagaacact tctcatgaca
    24781 tccatagtga ttatctcttc atgtcatatt gggcgacggc tttctgccca tcagaaatag
    24841 ccaggcctgc atcttgcgat accggcccgg cttgttatca acacttaatg ggttttgatg
    24901 tagccgcgca cgcactcttc gactaatccc cagaaccagt ctgtatcaat agtgatgccg
    24961 actttggtat tggcgggctt gccaagaacg cccagctcgt cgcagacggt acgcccatag
    25021 caagggccac tgttgacgtc cacttcgacg tacatctcct gggttttaat gccatcaggg
    25081 ttaatcagat aaccgatgca ggtggcgtcg tgcaccgggc cgccagcaag gccgtagttt
    25141 tcgaactgcg ttttgagagt gaagttcatg atgtcgctga acagctctcc ggcggggccg
    25201 cctgcccttt ccatccgagc aatcacgtcc ggggtgcaaa cggtctggtt ggtgagatcg
    25261 aggcccatca tcactaatgg aacgccggag gtgaacacta cgcgtgcggc ttccgggtcg
    25321 gcaaagatgt tgaactcggc agatggcgtg aagttgcctg taccgtaagc gccgcccatt
    25381 agcacaattt cacggatttt gggcaggatc gcgggttgca tacgcattgc caccgcgata
    25441 tttgaaagcg gaccaaccgg caccagagtg atatcgccat cgcttgccat cagggtatca
    25501 atgatatatt tcaccgcatg agtgctttct gcctggcggg tcagcggctc gaataccggg
    25561 ccatccagtc cggtttcacc gtgaatatta tcggcaacga tttgttgacg cataatgggc
    25621 tgcggcatcc ccgcataaac cggaacatta atctccagtt tctggcaaac attcaggcca
    25681 ttaattaatg ttttatcaag cgtctgatta cccgctacaa tagtgatgcc taataaatct
    25741 attgccggat gtttcgccgc catcattata gcaatagcat catcatgacc cggatcacaa
    25801 tccagaataa tttttctctt ttccattgtt tatttcctct gtttccagtt gcgttatttt
    25861 ttctacagca aagaaaattc gaccgggccg atgattgaat cttaacaaca gcgtacgtat
    25921 gctaaatatg agaaatctca tagcggataa acatcgtgaa agaaatccac aataatgatc
    25981 ttaagcagca attgatgagt gaatccgcgt ttaaggattg ctttttaacg gatgtttcag
    26041 ccgatacgcg gctgtttcat tttttagcgc gtgactacat tgtgcaggaa gggcaacagc
    26101 cgtcctggct gttttacctg acgcgaggcc gcgccaggct ttacgccacg ctagctaatg
    26161 gtcgcgtgtc gctgatcgat ttctttgccg ccccctgttt tattggcgag attgagttaa
    26221 tcgataaaga ccatgaaccg cgtgcggtgc aggctattga agagtgttgg tgccttgcgc
    26281 tccctatgaa acattaccgt ccgctgttat taaacgacac gctattttta cgaaaactct
    26341 gcgtcacctt aagtcataaa aattatcgta atattgtttc tttaactcag aatcaatcat
    26401 ttccgttagt gaatagcctg gcagcattta tattactctc gcaggaaggt gatctttatc
    26461 acgaaaagca tacgcaagcg gcagagtatt taggcgtttc ttatcgacat cttttatatg
    26521 ttctcgcgca gttcattcac gacggtttat taattaaaag caagaaaggg tatctcatta
    26581 aaaacagaaa gcagttgtca ggactggcgc tggagatgga cccggagaat aaattctccg
    26641 ggatgatgca gtaaaaatta ttttcaatag cgcgattgcc ggatgcaacg cttaatacgt
    26701 tttatccggt ctacaaatcg agcattacgc cagaccaata aagaacccgg caatagtcgc
    26761 actcatcagg ttggaaagcg ttgctgctgc cagcgcccgt aaaccaagct gggcgatttc
    26821 cggcgcgcgt tttggcgaaa tagccgaaaa tgcgccaacg acaacaccga tagaaccaaa
    26881 gttagcaaaa ccacaaagcg caaaggagat aatcgcaatg gttttcactt ccagcgtgcc
    26941 gcccgtttgc aggtatgggg agaaactcag gtaagcgacg aattcgttaa tcgccagttt
    27001 ctgcccaatc aggctacccg caagattggc atcactccag tccacaccca tgatccacgc
    27061 cagcggtgcc agcacatagc caaaaatact ttccagagag gcattggcga aaccaaacca
    27121 gccgccaatt ccgccgataa tgccgttgat cagcgcaata attgcgacaa acgccattac
    27181 caccgtcgcc acaccagcgg cgatttttag cccggtcatc gcaccgctcg ccgccgcttc
    27241 gataaagctt tttggcggcg tttcgctgaa cgacagattt tcaaatgtga cctgcgaagg
    27301 ctcggttgcc gggctaagaa tacgtgcaaa caaaatcccg ccagggatcg ccatcagcga
    27361 tgccgctaac aggtagtcaa ttggtacgcc cattccggca taaccaatca tcatcgaacc
    27421 agcaatggac gccatcccgc tacaaattgc ggtaaacaac tcgttgcgat tcatgcgatc
    27481 gataaacggt ttaacgatcg ccgggatctc attttgcccg aggaaaatag tagtaaccgc
    27541 aacaaaagat tcgattttgc tgatgttgag ggctttctgg aaaatgctgc caaggatgcg
    27601 aatcagcagc cccatcacgc caatgtagta cagcagactg atgagcgcag taacgaaaat
    27661 aatcgccgga agtacgcgaa aggcgaagat aaaacccgca ccgtcaaaca ggacatccat
    27721 tttcggccca accagcgaac caaaaatgaa ggcgctaccg gcatcactgt aagacatcac
    27781 tttatgaacg cctaatgccg cctgttctac tgcccatttt cccggtggga agtagagcat
    27841 gatgccacca atagcgattt gcagcagcag tgcggctcca accgtgcgca aactgatgct
    27901 ctttttattc actgacaaca gaaatgctat tgccagtaac accaccatcc ccacaacact
    27961 tctcattata tccataatga ttttcccttc atgccggtaa acccggcgtc agcgccaggt
    28021 tttggtatgc ttgatgagta cgggcgacgg ctttctgccc gtcagaaatt aacccgcgag
    28081 acgctgatat tctttggcaa tttcgctcgc cagaatggcg ttgttgaaca ccagctggat
    28141 gttggatttc aggctgtcac cgccggtcag ttcagcaacg cgcgccagca ggaatggcgt
    28201 actttcttta ccaatgactc cctgagcttc agcttcagct accgcctgat cgatcgccgc
    28261 attgatagtg tgttccggca tagcaaactg ttccgggatc gggttcgcta ccacgaggcc
    28321 accgttcaga ccgctttgcc atttcaccgc cattgcacgg gcaatttcgc tggcgctgtc
    28381 gagacgaatg ctgacgtcaa acgggctggt gcggcagaaa aacgcaggca gcgctttagt
    28441 ctgatagcca attaacggca caccgaaggt ttctaaatac tcagtggtta atcctaaatc
    28501 gagaatagat ttcgccccgg cacaaacaac ggtgacatta gtatttgcca gttcttgcaa
    28561 atcggcagaa atatcgaagg tatgttccgc cccgcgatgc acaccaccaa ttcccccggt
    28621 ggcaaatact ttaattccgg caagcgccgc aataatcatc gttgaagcca cagtggttgc
    28681 gccatttttt ccggcggcaa caacaaaagg taaatcgcga cgactaactt tggtcacgtt
    28741 atgcccttca cgacccagta attcaatttc ttctttgctt aaccccactt tcatcacgcc
    28801 gccaataatg gcgatcgtgg caggtacagc gccctgttta cgaatagttt cttcaacttc
    28861 aattgcggtc tgggcatttt gtgggaacgg catcccgtga gaaataatgg tcgattccag
    28921 cgccacaacc ggttttttgt tttttaaagc gtcctgcact tccggggaaa tttgtaataa
    28981 ttcaggggaa atttttaatt cagacattct gcgttctcca ctaacgatat aacgttggca
    29041 atcgataaat cggggttatt ggtgtattca caggagagcg ccattgacga acatccctgt
    29101 gcgaaacgaa cagattcggc aaacggcatt ccgtctaccc aacacgaagc aagtcccgcc
    29161 atcatggcat cgcccgctcc ggtaacatta ataacattgg ttttgatcgg cgcagaccag
    29221 ccactttcac cgctgatatc gctgtaataa acgccgtcgc cgcccatgct caataccagt
    29281 cggttcaggc catgttgatg gaaccaggca gcaacttttg ccacatcttc acgccctgac
    29341 agcgcaatcc cactcagggt ttccgcttca aggcggtttg gcttgagagt gtggttctga
    29401 tttagacggt cgcgcacttt gacacatttc catgccgaaa ccggatcgac aaatacgggt
    29461 acgttggcgg cattatccag aatccatgcc agtgcctctt cactgatatt acagtccgcg
    29521 acaatgacct ttgccctctg aataaattca ccgtgctgtg cgagatattc agctgtaata
    29581 gcgttgctaa tattcatgtc atttatagca accagcattt caccggtatt atcgagtaat
    29641 gataaataac tcgacgtatt ttctcccggc acaatcaggc atttatcgac ataaacgcca
    29701 gattgattgg tttgcgttag cagcgattga ccataaaaat cactgcctac ggcgctcagt
    29761 agccaggctt tgttacccag caacgccagg ttttgtgcaa tattgcgccc tactccacca
    29821 ggcgtaaatt ttattttacc tggatttgaa tccgcataat ttaatgattc atgtgaatat
    29881 ccggcgacat caatattcgc cgaacctata attacgacat aatccttttc gcgcatagca
    29941 cgtcctctgg taaaaaatta ccaaccctgt caatccacaa gaatatagat actgcaaaga
    30001 cggtttaaac atgtgttcat atttaaacat gtgctcatag tatgcatgtt ttacgtaaag
    30061 taaattaccg ccagagaggc aaaatgggca gatttgagca ggctcacaaa atgcgattaa
    30121 atgcctgaat tacaaaagcg aggaatttgt gacgggatgc acagaacaga acaataaaaa
    30181 agggcagaaa ataatctgcc cttgaggaaa taacctgagt gtttgatgaa cgtttgaagt
    30241 ttctactgaa agataaaacc atttaaattc ataaaattac attcacaaac cggtcattct
    30301 ctttgcgctc atcaaatgtt acaggacagg aaatttctgc cctgtaacac accttttatt
    30361 acgctgcttt cgctactgcg tccacttccg gacgtttcag gaaggcatag gccaaacccg
    30421 ccaccagcgt accggcaata attgctacca ggtaacccaa taccggcgta atagcgccag
    30481 ggatcagcag aacaaacaga ccaccgtgcg gtgccatcag tttcgcacca atcgccattg
    30541 agattgcgcc agtcagcgcc ccacccacga tacagcacgg cagcacacgc atcggatcac
    30601 gagcagcaaa cggaattgca ccttccgaaa tgaagcacag tcccaatacc agagcggctt
    30661 tgccaccttc ctgctgcgct ttgtcgaatt tgcgacgcgc caccattgtt gccagaccca
    30721 ttgccagcgg tggcaccata cctgccgcca taatcgccgc catcgggcca taggtttgag
    30781 tactcagcag acccacaccg aatgcgtacg ctgctttgtt taccggaccg cccatgtcag
    30841 tacacatcat gccaccgagg atcgccccca gcagaaccgc attcgcagtc cccatggtct
    30901 gcagccagtg agtcagccct tcgagaatgc cagcaactgg tttaccgatc aggtagatca
    30961 tcgccagacc gaccaccaga ctggaaatta gcggaatgat caggatcggt ttcagcgcct
    31021 ccatactctg tggcagtttc aattgcgtac tgattaactt cgcaatgtaa ccagccagga
    31081 agcccgcaat aataccacca atgaagccag aaccggtgct gaccgccagc ataccgccaa
    31141 tcagacccgg agtgaggccc ggacgatcgg caatggaaaa ggcaatataa cctgccagta
    31201 ccggcaccat cagcgcaaag gctgaaccac caccaatctg catcagcgcc gcagccaacg
    31261 tacccggctc tttaaacgct tcgataccaa aagcaaaaga aagcgcgata cacagaccac
    31321 ctgcaacgac catcggcagc atgtaagaaa cgcccgtcag caagtgacgg tatgcgcctg
    31381 cactctcttt cttactttca gtggtcgccg tttgagcttt gcccgccggt tcatacggcg
    31441 ttgcttcagc aaccgcttta tccagttcct gcgcggtttt cttcagcgcc agaccggtag
    31501 aggtacgata catcggttta ccagcaaatt tcgccagatc cacttcgata tctgccgcca
    31561 caatcaccag atccgctgct gcgacttctt cgggagtgat tgcattaccc gcgccaacag
    31621 aaccacgggt ttcaactttc acccaccagc cacgtttttt cgcttcggtt tcaatggctt
    31681 cagccgccat aaaggtgtgt gctacgccag tcgggcaagc agtcaccgca actacgcgtt
    31741 tcggaccgct ggcggcaact ggtgctgtcg cagcgaccgg cgcagtgtaa ggtttcgcat
    31801 ggcctttggc ttcactcagg aacagctcag ggtgcgcaac tgcccgggaa atatcgccca
    31861 gccagacatt tttaccgttc agcgcgctgt cgttcgggat ggaatcaccg agaacaatcg
    31921 ccatttcagc gtcgttcgga ttgtcgatga tttccagttt tgcttttcgc gccgccgcgc
    31981 ccagcagggt cttcgccata taggcgcgtg cctgaccgag attagcgtca ataatcagca
    32041 gcgttttcat tatgcctctc ctgctgtcag ttaaaaggtt gtaagtcgac gcgcgccatc
    32101 attgcggcca actgcggacg atcggtaata cccacattgc tttgacttac cgccagggct
    32161 gcaacagctg tcgccagacg cagtgtgtgt tcactggatt cacgcatcag caagccataa
    32221 atcaggccac caaccataga atcccctgcg ccaacggtgc ttacgacatc gactgacggt
    32281 ggtttggcga tccattcgcc ggaggcatta acccaaagcg cgccttcggc acccagtgaa
    32341 ataacaacat gcgcgatgcc ttgttcacgt agcgcatgtg cagcttcaat cacatctttc
    32401 atttcaggca gtttacggcc tgcccagatt tccagctcgc ggcggttagg tttcaccagc
    32461 cacggtgccg ctttcaaacc tgctactaac gcttcacggc tactatcaaa gataatgcaa
    32521 ggacactgac tacgcaggcg agtcatccag tcggtgaacg cttccgggct gacgcctgac
    32581 ggtaagcttc cgctgacaca gaccatatcg aactgaccga gccagctcag agaatcagtc
    32641 acaaagcgtt cccagtcggc gggggtgact tcaaaacccg agaagttgaa gtcggtcact
    32701 tcgccgtctt tttccgtcag cttaacgtta attcgggtgc gcccctgtac aacctggaaa
    32761 cggttggcaa tgcccagctc gctgaacagt tgctgaaaac catcctgatt gtctttaccc
    32821 aggaagccgc caacggtgac atcaattccc aggtctttta atactttggc cacgttgatg
    32881 cctttacccg ccgcatgcag accggtggtt ttcaccaggt tcacttcgcc gcgttcaatt
    32941 tccgggcaga aaccaacaag gtcataagcc ggattaaggg tgatagtagc aacacgtctg
    33001 ctcattatgc gccctcccca agaccagcag cgatagcgtc gccgattgct ttcagcgcct
    33061 gttcagcatc tgcaccctgg gcggtaaagc gtaggcgatg acctttctta acgccaagtg
    33121 ccacaacttt catcagacta cgtccgtttg ccggtttgcc ggtaccatca aggtttgtca
    33181 cggtaatatc actgttaaat tgtttaatgg tattgaccag catggtacct ggacgagcat
    33241 gcaggccgtg ttcattgcgc accacaaact ccgcgcttaa cacgtcgtcg gtcggcgcat
    33301 catcgctggt cagcagcgcc agcaacgttg ccgcatccgc tttcagcaag cggtcagctt
    33361 tattgtcgag caataaatca gcgagacgct taagaaccgc gatgggctga tcgtcattca
    33421 tcgccacact caccagcatg gctgccgttt cgccgtccac atcaaaagca tttgccgcac
    33481 ggcttaccgc aatcgcgcta cgcagattgc cttcggcgct atcgctcagc cagataccct
    33541 gtccgagatt cagcggttgt tcattgatgg ctttggtgac gaaagtggcg tcaactgccc
    33601 ccgcctcttt cagacgcgca gcgttcagcg cctgaagagt cagcagatcg ctggcgacga
    33661 tatccagtgt cagcatttcg ttgtcgagct tcagctgctc actctgcttt tcgcccatca
    33721 gtaatgcgcg aagttcttct gctgttgttg ctgacttcag ttgttcagca acggaatcat
    33781 cgctcagtac gtgggtcagc tggcgtagca ggcccagatg ttcatccgag ctggcagcaa
    33841 taccgattgc cacgtacgct acctgaccgt caccccaggt gacgccttcc gggaactgaa
    33901 atacctgaac gccggttttc agcacctgat cgcgggtgtc ggtagtgccg tgtggaatag
    33961 caataccatt gccgaggaac gttgaggttt gctgttcgcg cgccagcatg ccattgacgt
    34021 agccttctgc tacattaccg gcctgcacca gcgccgcagc gacctggcga atcgcctctt
    34081 ctttgtctcc ggccttttcg cccggatgga tgtcctgtac ggataactgg aacatagttc
    34141 tcctctcttg ctgaattgaa acgattcagc ctctatgaga aaaaaagcgc caacctggct
    34201 tagggttaaa gacaagatcg cgctgaaacg tttcaagaaa gcataatact tctgtttcag
    34261 cacgcaagga aagccgtaaa gttatgagca aaagtttgat gtgctgcaca attttttgcc
    34321 atttttccta attgctgatg ggaaaatccg ttatcagcaa tttcatttca gcagcgtcag
    34381 cagccaatca gcaacagtga aatggcattt tgactattcg tggcgctttt gatttcgctg
    34441 tctgtttatt ttctgacaag cagcgtaaac tccgcgtctt cctcttccag tgatcgacca
    34501 gcatgcataa ctcccccgca gtctccagcg cgaaatcgtt tgacctgacc tcgacggcgt
    34561 ttttaatcgt tgcctttctc accggtattg cgggcgctct gcaaaccccg acactcagta
    34621 tttttcttac cgatgaagta catgcccgtc cggcgatggt gggattcttc tttaccggca
    34681 gcgctgtcat tgggattctg gtaagtcagt ttctcgccgg gcgctctgat aagcgcggcg
    34741 atcgcaaatc gctgattgtc ttttgctgcc tgttaggcgt gctggcctgc accctttttg
    34801 cctggaatcg caactacttt gttttgctat tcgttggcgt ctttcttagc agctttggct
    34861 cgaccgctaa cccgcaaatg tttgcccttg cccgtgaaca tgccgacaaa accggacgtg
    34921 aggcggtgat gttcagctct tttttacgcg ctcaggtttc actggcatgg gtcattggcc
    34981 caccgctggc ttatgcctta gcgatgggtt tcagctttac ggtaatgtat ctgagcgcag
    35041 cggtagcgtt tattgtttgc ggtgtgatgg tgtggctgtt tttaccgtcg atgcaaaaag
    35101 agcttccgct ggcgaccggc acgatcgaag cgccgcgccg taaccgtcgc gatacgctgc
    35161 tgctgtttgt catttgtaca ttgatgtggg gctcgaacag cctgtacatc atcaacatgc
    35221 cgctatttat tatcaacgaa ctgcatcttc ccgagaaact ggccggtgtg atgatgggga
    35281 ccgccgccgg gctggaaatc ccgacgatgt tgattgccgg atatttcgcc aaacgtctgg
    35341 gtaagcgttt cttaatgcgc gttgctgccg tgggtggcgt ctgtttttac gcaggaatgc
    35401 tgatggcgca ttcacctgtc attctgttgg gcttgcagct gctaaatgct atttttattg
    35461 gcattctggg cggcatcggg atgctctatt ttcaggatct gatgcccggt caggcgggtt
    35521 cagccaccac gctctatacc aacacttcgc gcgtgggctg gatcatcgca ggatcagtgg
    35581 cgggcatcgt cgccgagatc tggaattatc acgctgtgtt ctggtttgcg atggtgatga
    35641 ttatcgccac tctgttttgc ttactgcgga ttaaagatgt ttaaggcgcg gtcagcattt
    35701 ccagatcgat aagccaggtc atggcctgct gacgcgagtt accgcacatt tcagcgctgg
    35761 cttgtaagcc tgcacagact ttcggtcgca gtggcgaggt gaaaatttta cagcgttgct
    35821 gttcatcaag ctgaatgcag ggcgtattgg cgggcttgcc atctggcata ccgggaatag
    35881 ggctggaaat tgaaggggca gtgcaacacg ccccgcaacc cggacggcat tccatacgtt
    35941 gttctcttaa ggttaaccac cggattgatg agcgcgcaca gtaccacctt ttttgcacca
    36001 gcaaaagtgc gaataccact tgcccgaaag gcccgtcgcg agtactttgt cgcgatattt
    36061 ttgacatttt cgactacagg aatttttcga tgccaagagc gaacgaaatt aaaaaaggta
    36121 tggtactgaa ttacaacggc aaactgctgc tggttaagga tattgatatt cagtcgccca
    36181 ctgcccgcgg tgccgctacg ctgtacaaaa tgcgtttttc tgatgtccgt accgggctga
    36241 aagtagaaga gcgtttcaaa ggtgatgata tcgttgacac cgtgacgctg acccgccgtt
    36301 acgttgactt ctcctatgtc gatggcaacg aatatgtctt tatggataaa gaagactata
    36361 ccccgtatac cttcaccaaa gatcagattg aagaagagtt gctgtttatg ccagagggcg
    36421 gcatgccgga catgcaggtg ctgacctggg acggtcaact gctggcgctt gagctgccgc
    36481 agaccgttga tctggaaatc gttgaaaccg caccaggcat caaaggggca tctgccagcg
    36541 cccgtaacaa accggcgaca ttgagcactg gtctggtgat tcaggtacca gaatacttaa
    36601 gcccgggcga aaaaattcgt atccatatcg aagaacgccg ttatatgggg cgtgctgact
    36661 aacttcagcc gcatgcagaa aagggatagc tcaggctgtc ccttttttaa tttattatac
    36721 caatcttcta ttttgcgctt cctgaacacc ttacgccctc aattttcact cgttgattga
    36781 tcgccctcac acttcatcgc attaacaatc cagaccaatt tcaattgctg tcatataact
    36841 ttacactgtc gttgttaatt aatcgttact aagacgtgac tcatatgaat acaatcgcct
    36901 ccgttacgct cccgcatcat gtacacgctc cacgctatga tcgccagcag ttgcaatcac
    36961 gtatcgttca ttttggcttt ggagcctttc accgcgctca tcaggcgtta ctgaccgatc
    37021 gtgtgctgaa tgcccagggc ggcgactggg ggatctgtga aatcagcttg ttcagcggtg
    37081 atcaactgat gagccagctc cgcgcacaga accatttata taccgtgctg gagaaaggtg
    37141 cggacggcaa tcaggtgata attgtcggtg ccgttcacga atgccttaat gcaaaactgg
    37201 attccttagc ggcaattatt gagaaatttt gcgagccaca ggtggcaatt gtttccctga
    37261 cgattaccga aaaaggctat tgtattgacc cggccaccgg tgcactcgac accagtaatc
    37321 cgcggattat tcacgatcta caaacccctg aagaacctca ctccgcaccg ggtattctcg
    37381 tcgaagcact gaaacgccgc cgtgagcgcg gccttacacc gtttaccgtg ctctcctgcg
    37441 acaatattcc cgacaatggt catgtggtga aaaacgcggt gctgggaatg gcagaaaaac
    37501 gttcgccaga actcgccggg tggataaaag agcacgtcag ttttccggga accatggtcg
    37561 accgcattgt tccggctgca accgacgaat cactggtgga aatcagccag catctggggg
    37621 tgaatgatcc ctgcgcgatt agctgcgaac cgtttatcca gtgggtggtg gaagataact
    37681 tcgtcgctgg gcatcctgcc tgggaagtcg caggtgtaca aatggtgaat gatgtcctgc
    37741 catgggaaga gatgaaactg cggatgctta atggcagcca ctcttttctc gcttatctgg
    37801 gttacctctc aggattcgcc catatcagtg attgcatgca ggatcgcgca tttcgccatg
    37861 ccgccagaac attaatgctg gatgagcaag cgccgacact gcaaattaaa gatgtcgatt
    37921 taacacaata tgcggataag ttaattgcac gttttgctaa tccggcgctg aaacataaga
    37981 cctggcaaat cgcgatggat ggcagccaga aattaccgca acgcatgctg gcaggtattc
    38041 gcatacatca ggggcgcgaa acggactggt cgttgctggc attaggcgtt gcaggctgga
    38101 tgcgttacgt cagcggcgtt gatgatgccg gaaatgccat tgatgttcgc gatccgctta
    38161 gcgataaaat tcgcgaactt gttgcgggca gcagcagtga acaacgcgta accgccctgc
    38221 tttccctgcg tgaagttttc ggtgatgatc tgccagataa cccgcatttt gtgcaggcca
    38281 tcgaacaagc ctggcaacaa atcgtacaat tcggcgcaca tcaggcgcta ttaaacaccc
    38341 tcaaaattta acgatttctg cggttaaagc ggatgaagct caccttcgtc cgctctcccc
    38401 ttctcttttc tgcctttttt agccaggatt aacgctcagt taacttacca gagtattgcg
    38461 gagccgttgt gaccaggacc aacctcatca ccggttttct cggcagcggg aaaaccacgt
    38521 cgattcttca tctgttagcc cataaagatc ccaacgaaaa atgggcggta ctggttaatg
    38581 aatttgggga agtcggaatt gatggtgctt tgctcgccga tagcggcgca ttgctgaaag
    38641 agatccccgg cggctgcatg tgctgcgtta atggtttacc catgcaggta gggttgaata
    38701 ccttactgcg tcagggaaaa ccagaccgct tgttgataga gccgaccggg ctgggccatc
    38761 cgaaacagat cctcgatctg ttaaccgcac cagtctatga accgtggata gatctgcgcg
    38821 ccaccttgtg cattctcgat ccgcgcttgc tgctggacga aaaaagcgcc agcaatgaaa
    38881 acttccgtga ccagctggct gccgcagaca tcattgtcgc caataaatcc gaccgtacga
    38941 cgcccgaaag tgagcaagcg ctacagcgtt ggtggcagca aaatggtggc gatcgacaat
    39001 taattcacag tgagcatggg aaagttgacg gtcatcttct ggatttgccg cgtcgcaatt
    39061 tagccgagtt gcccgccagc gccgcgcatt ctcatcagca tgtcgtgaaa aaagggttag
    39121 cagcgttaag cctgccagag catcaacgct ggcgtcgcag tctgaacagc gggcaaggat
    39181 atcaggcctg cggctggata ttcgacgctg atacggtatt cgacaccatt ggcattctgg
    39241 aatgggcgcg acttgcaccg gtggaacgcg tcaaaggcgt gctgcgtatt cccgaagggc
    39301 tggtgcgaat caaccgtcag ggcgatgacc tgcacattga aacgcaaaac gttgcgccac
    39361 cggacagccg tattgagctg atttccagca gcgaagctga ctggaatgcc ttgcagagcg
    39421 cgctgttgaa gcttcgttta gcgactaccg cgtaaggttg cctgcgtttt tcagtaagat
    39481 aattagagaa aatatgatta aaaatttgcc gcaaatagtg ttgttgaata ttgtcggcct
    39541 cgcgctgttt ctttcctggt atatccccgt taatcatgga ttctggttgc cgattgatgc
    39601 ggatattttt tatttcttta atcagaaact ggtcgaaagt aaggcctttt tgtggctggt
    39661 tgcattgacc aacaatcgcg ccttcgacgg ttgttcactg ctggcgatgg gtatgttgat
    39721 gctgagtttc tggctgaaag aaaacgcccc tggcagacga cgtatcgtga ttattggtct
    39781 ggtcatgcta ttaactgcag tggtattaaa ccagctgggt caggcattaa ttcctgtaaa
    39841 acgggccagc ccaacattga cttttaccga tattaaccgc gtcagcgaac tgctctctgt
    39901 tcccacgaaa gatgcctcac gagatagctt tcccggcgat cacggcatga tgctgcttat
    39961 tttttcggca ttcatgtggc gttatttcgg caaagttgca ggccttatcg cccttattat
    40021 ttttgtggtt tttgcatttc ccagagtaat gattggcgca cactggttta ctgacatcat
    40081 tgtcggttcg atgaccgtga tattgatcgg tttgccctgg gtgttgctga cgccattaag
    40141 tgatcgatta atcacctttt ttgacaaatc actaccagga aaaaacaaac atttccaaaa
    40201 caaataactc acagtaatta acatcatcag ggttattttt atagtgagga taatcctgat
    40261 gatgcgcacc gtgctttcat ctatcgaacg caaaaatcat tctctaagta aatgaatgga
    40321 ttgcatgcgt ttcactcaat tgtactttaa ttgaccaacc ccgcttatta actttctgta
    40381 tcactttttc ttataaaaaa tcatgtaaaa ccgctcgcca agaccgcacc aatcgggtaa
    40441 tctcgaactc gttttgcctc ggcggtagat tatcctcaca gcatataatt ttgtgcgtta
    40501 gtccacagat ttggccttaa ggaattgttt caacatgccc aggtaattag tctcgtgtcg
    40561 cttggcattt ttttataacg atatttgtcg ttaaggactt caagggaaaa caaacaacat
    40621 ggtcaaatct caaccgattt tgagatatat cttgcgcggg attcccgcga ttgcagtagc
    40681 ggttctgctt tctgcatgta gtgcaaataa caccgcaaag aatatgcatc ctgagacacg
    40741 tgcagtgggt agtgaaacat catcactgca agcttctcag gatgaatttg aaaacctggt
    40801 tcgtaatgtc gacgtaaaat cgcgaattat ggatcagtat gctgactgga aaggcgtacg
    40861 ttatcgtctg ggcggcagca ctaaaaaagg tatcgattgt tctggtttcg tacagcgtac
    40921 attccgtgag caatttggct tagaacttcc gcgttcgact tacgaacagc aggaaatggg
    40981 taaatctgtt tcccgcagta atttgcgtac gggtgattta gttctgttcc gtgccggttc
    41041 aacgggacgc catgtcggta tttatatcgg caacaatcag tttgtccatg cttccaccag
    41101 cagtggtgtt attatttcca gcatgaatga accgtactgg aagaagcgtt acaacgaagc
    41161 acgccgggtt ctcagccgca gctaataaac cgtttggatg caatcccttg gctatcctga
    41221 cgagttaact gaaagcactg cttaggcagt gcttttttgt tttcattcat cagagaaaat
    41281 gatgtttccg cgtcttgatc caggctatag tccggtcatt gttatctttt aaatgttgtc
    41341 gtaatttcag gaaattaacg gaatcatgtt catacgcgct cccaattttg gacgtaagct
    41401 cctgcttacc tgcattgttg caggcgtaat gattgcgata ctggtgagtt gccttcagtt
    41461 tttagtggcc tggcataagc acgaagtcaa atacgacaca ctgattaccg acgtacaaaa
    41521 gtatctcgat acctattttg ccgacctgaa atccactact gaccggctcc agccgctgac
    41581 cttagatacc tgccagcaag ctaaccccga actgaccgcc cgcgcagcgt ttagcatgaa
    41641 tgtccgaacg tttgtgctgg tgaaagataa aaaaacattc tgttcatctg cgaccggtga
    41701 gatggacatt ccactcaatg aattgattcc ggcgctcgac attaataaaa acgtcgatat
    41761 ggcgatctta cccggcacgc cgatggtgcc gaacaaaccc gcaatcgtca tctggtatcg
    41821 caaccctttg ctgaaaaata gcggcgtctt tgccgctctg aatctcaacc tgacgccttc
    41881 actcttttat agttcacggc aggaagatta cgatggcgtc gccctcatta ttggcaatac
    41941 tgcgctatct accttttctt cacgtttgat gaacgttaac gaattaaccg acatgccagt
    42001 ccgtgaaact aaaattgcgg gcattcctct gaccgttcgg ctttatgcag atgactggac
    42061 atggaacgat gtgtggtacg catttttact gggcggcatg agtggaactg tcgttggcct
    42121 gctctgctat tacctgatga gcgtacgtat gcgccccggc agagaaatca tgaccgccat
    42181 caagcgcgaa caattttacg tggcgtatca accggtggtg gatacacaag ctttgcgagt
    42241 aacgggcctg gaagtactgc tacgctggcg gcatcctgtc gcgggagaaa ttcccccgga
    42301 tgccttcatt aactttgccg aatcgcaaaa gatgattgtg ccgctgactc agcacctgtt
    42361 tgagttaatt gcccgcgatg ccgcagaatt agaaaaagtg ctgccggtag gcgtcaaatt
    42421 tggtattaac attgcgccgg accatctgca cagcgaaagc tttaaagcag atatccagaa
    42481 actgctcact tccctgcccg cacaccattt ccagattgtg ctggaaatta ccgagcgcga
    42541 tatgttgaaa gagcaagaag ccacacaact cttcgcctgg ctgcactcgg tcggcgtaga
    42601 aattgctatt gatgacttcg gcaccgggca cagcgcgctt atctatcttg agcgttttac
    42661 gctcgattat ctgaaaattg accgtggatt tatcaacgcc atcggtacgg aaacgatcac
    42721 ttcccccgta cttgacgcgg tgctgacgct ggcgaaacgc ctcaatatgc tgacggttgc
    42781 tgaaggggtc gaaacgccgg aacaggcgcg atggctaagc gaacgcggcg ttaatttcat
    42841 gcaaggctac tggattagcc gcccgttacc gctggacgat tttgttcgct ggctaaagaa
    42901 accgtatacg ccgcagtggt aaggtgtgct tacgtccctt attattcata gtgaaagcat
    42961 gccggattgc ggctaatgat gagtaaaagg aaatccgttg cagatgattg tgcgcatact
    43021 gctgctgttt atcgctctgt tcacctttgg tgtgcaggcg caggctatca aggaaagcta
    43081 tgcctttgcc gtgctgggcg aaccccggta cgcgtttaat ttcaaccatt ttgattatgt
    43141 gaaccccgcc gcgccaaaag gtgggcagat aacgttgtca gccctcggca ccttcgataa
    43201 tttcaaccgc tatgcactgc gcggcaaccc gggcgcacgc accgagcagc tgtacgacac
    43261 gctatttacg acttccgatg acgaaccagg cagttattac ccgctgattg ctgaaagcgc
    43321 acgctatgct gacgattatt cctgggtgga ggtcgctatt aatccgcgcg cccgttttca
    43381 tgatggttcg cccattactg cccgcgatgt agagtttact tttcaaaaat ttatgaccga
    43441 aggcgtgccg caatttcgtc tggtctacaa aggcaccacc gtcaaagcca ttgcaccgtt
    43501 aaccgtgcgc attgagttag ctaaacccgg caaagaagat atgctgagtc tgttttcgct
    43561 gccggtattt ccagaaaagt actggaagga tcacaaactt agcgacccgc tcgccacgcc
    43621 tccgcttgcc agtggtccgt accgcgttac gtcctggaaa atggggcaaa atattgtcta
    43681 ttcccgtgtg aaagattact gggcagcaaa cttaccggta aaccgtggac gctggaattt
    43741 cgacaccatt cgctacgatt attacctcga tgataatgtc gcctttgaag cgtttaaagc
    43801 aggtgccttt gatttgcgta tggaaaacga cgccaaaaac tgggccacgc gttataccgg
    43861 taaaaatttc gataaaaaat acatcatcaa agatgagcaa aagaacgaat cagcccagga
    43921 tacgcgttgg ctggcgttta atatccaacg tccggtattc agcgatcgcc gggtccggga
    43981 agctatcact ctcgcctttg actttgaatg gatgaacaag gcgttgtttt acaatgcctg
    44041 gagtcgcacg aacagttatt ttcagaatac cgaatacgcg gccagaaatt accccgacgc
    44101 cgcggagctg gtgcttctgg caccaatgaa aaaagatcta ccgtcagaag tcttcacaca
    44161 aatctaccag ccgccggtat ccaaaggcga tggctacgat cgtgacaacc tgttaaaagc
    44221 cgacaaactt ctcaacgaag cgggctgggt gctgaagggt cagcaacgcg ttaatgccac
    44281 aacgggtcag ccactcagct ttgaattatt gcttcccgca agcagcaata gtcagtgggt
    44341 attgccgttc cagcacagcc tgcaacggct gggtatcaac atggacattc gcaaggtgga
    44401 taactcgcaa atcactaacc gcatgcgcag tcgcgactat gacatgatgc cgcgcgtatg
    44461 gcgggcgatg ccgtggccca gttccgattt acagatttcc tggtcatcgg aatatatcaa
    44521 ttccacttat aatgcccccg gcgtgcaaag cccggttatc gactcgctga tcaaccaaat
    44581 tattgccgcg cagggaaata aagaaaaatt actgccgttg gggcgagcac tggatcgcgt
    44641 attaacgtgg aattattaca tgctgccaat gtggtacatg gcggaagacc gtctcgcctg
    44701 gtgggataaa ttctcccagc cggccgtgcg ccccatctat agcctcggta tcgatacctg
    44761 gtggtatgac gtcaataaag cggccaaact gccgtccgcc agcaaacagg gagagtagat
    44821 gggcgcttac ctgattcgcc gtctgttgct ggtgatccca acattatggg cgattatcac
    44881 catcaacttt ttcatcgtgc aaattgcgcc tggcggtccg gtcgaccagg ccatcgccgc
    44941 cattgagttt ggtaatgccg gagtattacc cggcgcaggc ggtgaaggtg ttcgtgccag
    45001 ccatgcgcaa acgggtgtcg gcaatatcag cgacagtaat taccgtggcg gacgcggatt
    45061 agatccagaa gtgatcgctg agatcactca tcgctacggt tttgataagc cgatccacga
    45121 acgttacttc aaaatgctct gggactacat ccgctttgat tttggcgata gcctgtttcg
    45181 cagcgcctcg gtgctgacgc tgattaaaga cagtctgccg gtttccatca ccctcggatt
    45241 gtggagcacg ctgattatct atctggtgtc gattccgtta ggcattcgca aagctgttta
    45301 taatgggagc cgctttgacg tctggagtag cgcatttatc atcatcggct acgccattcc
    45361 ggcctttttg tttgccatcc tgctgattgt cttcttcgcg ggcggcagct atttcgacct
    45421 gttccctcta cgcggcctgg tttccgctaa ctttgattcg ctgccgtggt atcagaaaat
    45481 caccgattat ctgtggcata tcacgctgcc ggtgctggcg acagtgattg gtggctttgc
    45541 ggcgctgacc atgctgacaa aaaactcatt ccttgatgaa gtgcgcaagc aatacgtggt
    45601 gaccgcgcgt gcgaaagggg taagtgaaaa aaatattctc tggaaacatg tgttccgcaa
    45661 cgccatgctg ctggtgattg ccggttttcc ggcgacgttt atcagcatgt tttttaccgg
    45721 ctcgctgctg attgaggtga tgttttcact caatggtctg ggcttactgg gctacgaagc
    45781 gaccgtctcg cgcgattatc ctgtaatgtt tggtaccttg tatattttca ccctgattgg
    45841 cctgctgctg aatattgtca gtgatatcag ctatacgctg gttgatccgc gtattgattt
    45901 tgagggacgt taatgtcgcg actcagcccc gtcaatcagg cccgttgggc gcgttttcgt
    45961 cataaccgtc gcggctactg gtcgttatgg attttcctcg tcttgtttgg tttgagtttg
    46021 tgttctgaac ttatcgccaa cgataaaccg ttgctagtgc gttatgacgg cagttggtat
    46081 ttcccgttat tgaaaaacta cagcgaaagc gattttggcg gcccgctggc aagtcaggct
    46141 gattatcagg acccgtggct gaaacaacgg ctggaaaata acggctgggt actgtgggca
    46201 ccgattcgct ttggtgctac cagtatcaac tttgctaccg ataagccctt cccttctcca
    46261 ccctcccggc aaaactggct gggaacggat gccaacggcg gcgatgtgct ggcacgcatt
    46321 ctctatggca cgcggatctc ggttctgttt ggcctgatgc tgactctctg ttccagcgtg
    46381 atgggcgtgc tggcgggggc gctacaaggc tattacggcg gtaaagtcga tctctgggga
    46441 caacgcttta ttgaagtatg gtcggggatg ccgacgctgt ttttgattat tttactttcc
    46501 agcgtcgtac agcctaactt ctggtggctg ctggcaatta ctgtcttgtt tggctggatg
    46561 agtctggtcg gcgtggtgcg ggcggagttt ttacgtactc gtaatttcga ctacattcgt
    46621 gcggcacagg cgcttggcgt cagcgatcgc agtatcatcc tgcgtcatat gttgcctaat
    46681 gccatggtcg cgaccctcac ctttttaccg tttattttat gtagttcgat aaccaccctg
    46741 acctcgctcg atttcctcgg cttcggtcta ccgctcggtt caccgtcact cggtgaactg
    46801 ctgttacaag ggaaaaataa ccttcaggcc ccgtggcttg ggatcaccgc cttcttgtcg
    46861 gtggcgatat tattgtcttt gctgatcttt attggtgaag ccgtccgcga cgcatttgat
    46921 cctaataagg cggtgtagca tgacgcaaac tctgttagcg attgaaaatt tgtcggtggg
    46981 ttttcgccat cagcaaaccg tacgtacagt agccaatgat gtttcactac agattgaggc
    47041 tggcgaaacg ctggcgctgg tgggtgagtc aggttcaggc aaaagcgtta ccgcgctgtc
    47101 aattttacgc ctgctccctt ccccgccggt tgaatatctc tccggcgata ttcgttttca
    47161 tggcgaatcg ctgcttcacg ccagcgatca aacgttgcgc ggtgtacgcg gtaataagat
    47221 cgccatgatt tttcaggaac cgatggtgtc gttaaatcca ttgcataccc tggaaaaaca
    47281 gctttatgaa gtgctttcac tccaccgcgg gatgcgtcgg gaagcggctc gtggcgaaat
    47341 tcttaactgc cttgatcgcg ttggtatccg ccaggcggca aaacggctga cagattatcc
    47401 gcatcagctc tccggcggcg aacggcagcg ggtgatgatt gcgatggcgc tgttaacgcg
    47461 accggaatta ttaattgccg atgaaccgac caccgcactg gacgtctctg tccaggcgca
    47521 gattttacag ctgttgcgcg aactgcaagg cgagctgaat atgggcatgc tgtttattac
    47581 tcataacctc agcattgtca gaaaactggc ccaccgcgtg gcggtaatgc aaaacggtcg
    47641 ctgtgtcgag caaaattacg ccgctacgct atttgcatca cccactcatc cttacacaca
    47701 aaagctactc aacagtgaac cgtcaggcga tccagtgccg ttgccagaac ctgcctcaac
    47761 gttgctggat gttgaacagc ttcaggttgc cttccccatt cgcaaaggga ttttgaagcg
    47821 cattgtggat cataatgtgg tggtgaaaaa catcagtttt acgctacgag cgggtgaaac
    47881 actgggttta gtgggcgagt ccggttccgg gaaaagtacg acgggactgg cgctgctgcg
    47941 actgattaat tctcagggca gcatcatctt tgacggtcag ccactgcaaa atttaaatcg
    48001 ccgccagctg ttacctattc gtcatcgcat tcaggtggta tttcaggatc caaactcctc
    48061 gctcaaccca cgactcaacg ttttgcagat tattgaggaa ggcttacggg ttcaccagcc
    48121 gacgctttct gccgcacaac gcgaacaaca agtgatagcc gtgatgcatg aagtgggatt
    48181 agatcctgaa acacgccacc gttatccggc ggagttctct ggtggtcagc gacaacgtat
    48241 tgcgattgcc agggcattaa ttcttaagcc ctcgctgatc atacttgatg aaccgacatc
    48301 atcactcgac aaaacggtac aggcgcaaat attgacgcta ttgaaatcat tgcaacaaaa
    48361 gcatcaactg gcctatttgt ttatcagcca cgatttgcac gttgtccgcg cgttatgtca
    48421 tcaggttatc atactgcgac aaggggaagt agtggaacaa ggaccgtgcg cgcgcgtgtt
    48481 tgccacaccg cagcaggagt atacgcgtca gctactggcg ttgagctgac gcttaaaaag
    48541 gattgtagtt tgaaaagggt tcggcaattg ccacaccaaa atttttcaat cggcatgttg
    48601 cagcaaactc gtcctggcga tttacaaaca ggcacggctc accttcacac tccagcaccg
    48661 aacatggaac ttcgatgtcg cttaacgcct ggcttagttt atacatcacc gaccatgcat
    48721 tatcaccatc cgggctaagc aatttaagcg ccaccaggct gttgtcaccg cacggtccat
    48781 tttgcggaat cggttcaacc ttcgaacctg cgaaaccagc agaccagcga tagttctgcg
    48841 gcagtcgatg gacgattgag agttgtaatg aagtcactta ttttccccgg aagcacattc
    48901 acttcacaat ttgtttacat caattttaac acatcatcaa caatccgtct ttatacagat
    48961 cgtaaagatt gatgcctcgc ctgcgtggcc tctatggctc tgatttaagt aatatctgcg
    49021 ggcgtggtca cgtttgcggg gctatatgta cccgtttctg cgatctaact caaccttttt
    49081 aactacaatg atgtgacttt ttacataaat tgattttaca taaaataaac atatatcggg
    49141 ggaatgatag atttgtggtt gacatgcatc aacaaaggaa gccttttagc ttcctcgttg
    49201 tgcaatagat caccgttttt tcggccgact ggcgtacaga cagaagagaa tggagctggt
    49261 tgcgcagaat gcaattgacc aaatcatcgg ccatgcagag ttaaaggtcg caagagaaag
    49321 caatgcgcca acaattgccc ctatgccaaa acggaaggtt cctgccagcg aagatgccgt
    49381 tcccgccata tggggaaact catcaagaat gaccgccatc gcattggatg acaccatcga
    49441 cacgcagccc acaaacgccg caacgccaac caccagcgac caaaatccca gccccagcag
    49501 cgcactgatg accatccacg ctgccataat aaattgtatc cacaaccccg agcggaacat
    49561 atttaacgcg ccaatgcggc ggacgaagcg gctgttaaag atggtcatca cgaacagaaa
    49621 aacaatgttt agcgcaaagt aataaccaaa gttttccggc gcgacgtggt taatttcaat
    49681 ataaacaaac ggtccggcgc ttaagaatga gaacatcccg gcaaagctga aaccactggc
    49741 aagcatgtag ctcaggacac gtttatggcg gaacagcgcc gcaaagttac caatagtggt
    49801 acgaatgtga aatggctgac gacgctccgg tggtaaggtt tctttaatca ggaagaaaat
    49861 cattgccgaa gccagaatcg ccgctaatgc caggatccag aagatgtaat gccagctcag
    49921 ccacaccagc acccagccgc caactatcgg tgccatcagc ggtgcaatgg ttgtcaccag
    49981 catgacaaac gacatcatcc gcgagaactc ttctttcggg taaatatcgc gcatcagggc
    50041 gttaatgacc acgctggccg cagccgcagc cagcccgtgg aagaaacgca tcacaatcag
    50101 ctgatcgatg gtgtttgcca acgcacacgc caccgcggcg gcggcaaaca ccagcgtacc
    50161 gccgagcacc accggcttac gcccgaagct gtctgccatc ggcccgtaga ttaactgccc
    50221 caacgcaaag cccagaatat aagtactgag ggtcatctgc gtactgcccg ccggtacgcc
    50281 aaactgcgct gaaattaccg gtagcgcggg cagatacata tcaatcgaca gcggcatcaa
    50341 catggccagc aggccaagga taaaaacaat agcaaacgac gaatgctgtc gggtggtcac
    50401 aacgggctcc tgaaagtcat tgaaaagtta gacgacgctg gcaatttctt cttcagttaa
    50461 cggacgatat tcaccggggg ctaaatcagc atccagcgta ataccgccaa tacgttcacg
    50521 atgcagctca accacgtggt tacccacggc ggcgaacatg cgtttcacct gatgataacg
    50581 cccttcgctg atggtcagac gaacctgcgt tggggtaatc acttccagca ccgcaggctt
    50641 agtgagatct ttttcgttat gcagctgcac gcctttagca aattgctctg ccgtatcgtc
    50701 agctacaggt gattccagtg tcaccagata ggtcttctcg caatgatggc gcggagaagt
    50761 aatgcggtgc gaccactgac catcatcagt catcagcacc agaccggtgg tatcaatatc
    50821 caaccgcccc gccgcatgca gtttccacgc taccggttca tcaagaaaat agagcaccgt
    50881 tgggtgatca gggtcgtccg tggagcaaac atagccctga ggcttattga gcatgaagta
    50941 acgtggaccg tgttgctgcg ccagcgggtt gccatcgtaa gcgacatcat gttcaggaag
    51001 cagtttgaac gctgcattac ggacgatttc gccatcgacg gtgacacgat tgccgcggat
    51061 ttcacgcccg gcaatagcac ggctaacgcc gagttgctgt gcgataaatt tatcaagtcg
    51121 catgtgtgtg attttgcctg taaaaacgga ggtcgggcat tgacccgaaa atctgaactg
    51181 ttgtctgccc agtatagcgg tctaataaca tccctcaagg gaaaaagatc catggcatac
    51241 tattagcaga ataatctacc tacgcgagac catgattttt acacttcgcc catatcagca
    51301 agaagccgtg gatgccacgc tcaaccattt tcgtcgtcat aaaacccctg ccgttatcgt
    51361 gctgcccacc ggcgcaggta aaagcctggt gatagcggaa ctggcacggc tggctcgtgg
    51421 tcgcgtgctg gtgctggcac acgttaaaga actggtggcg caaaaccatg caaagtatca
    51481 ggcgctgggg ctggaagccg atatttttgc cgccgggcta aagcgcaaag agagccacgg
    51541 taaagtggta tttggcagcg tgcagtctgt cgcccgtaat cttgatgcct ttcagggtga
    51601 attttcgctg ttgattgtcg atgaatgtca ccgtattggt gacgatgaag agagccagta
    51661 tcagcaaatc ctcactcacc tgacaaaagt gaatccccac ttacgcctgc tggggctgac
    51721 tgccacgcct tttcgattgg gcaaaggctg gatctaccag tttcattatc acggcatggt
    51781 acgcggcgat gagaaagccc ttttccgtga ctgcatttat gagctgccgc tgcgttatat
    51841 gattaaacac ggctatctga cgccgccaga acgactggat atgccagtag tgcaatacga
    51901 tttcagccgc ttgcaggcac agagtaacgg gctgttcagc gaagccgatc tcaaccgtga
    51961 gctgaaaaaa caacaacgta ttaccccgca catcatcagc cagattatgg agtttgctgc
    52021 aacgcgcaaa ggggtgatga tttttgccgc gacggttgaa cacgcaaaag agattgtggg
    52081 attactgcct gccgaagatg cagcactgat tactggcgac acccccggcg ctgagcgcga
    52141 tgtgttaatt gaaaatttta aagcccagcg ttttcgctat ctggtcaacg tcgcggtact
    52201 gaccaccgga tttgacgccc cgcacgtcga tcttatcgcc attctgcgcc ctaccgaatc
    52261 agtgagtctt taccaacaaa ttgtcgggcg cggtctgcgt ctcgctccgg gcaagactga
    52321 ttgcttaatt cttgattatg cgggtaatcc tcacgatctc tacgcgccgg aagttggtac
    52381 accaaaaggc aaaagtgaca acgttccggt acaggttttc tgccctgcct gcggttttgc
    52441 caacaccttt tgggggaaaa cgaccgccga cgggacattg attgaacact ttggtcgtcg
    52501 ctgtcaggga tggtttgaag atgacgacgg tcatcgcgaa caatgtgact tccgtttccg
    52561 ttttaaaaat tgcccgcaat gtaacgcgga aaacgatatt gccgcccgcc gctgccgcga
    52621 atgtgacacc gtactggttg atccggacga tatgttaaaa gcggcgctac gactgaaaga
    52681 cgcgctggta ttacgctgta gcggcatgtc tttgcaacat gggcacgacg agaaaggcga
    52741 atggttgaaa atcacctatt acgatgaaga cggcgcggat gtgagtgagc gtttccgtct
    52801 gcaaacacct gcccagcgta ccgccttcga gcagcttttt atccgcccgc atacgcgcac
    52861 accgggcatc ccgctgcgct ggatcaccgc cgccgatatc ctcgcccagc aagccttatt
    52921 gcgacacccg gattttgtcg tcgcccgcat gaaaggccag tactggcagg tgcgtgaaaa
    52981 agtgttcgat tacgaaggtc gttttcgtct ggcgcacgaa ttacgcggtt aatggtagtt
    53041 ttgattgatg tataaggcga ttgagtatag aatctcgccc gcttttgcat acgcaaagca
    53101 gatcacttac ctgttgctgg gtcgcctgta gcaggattaa tttaagagag aaagaaatgt
    53161 ttactatcaa cgcagaagta cgtaaagagc agggtaaggg tgcgagccgc cgcctgcgtg
    53221 ccgctaacaa gttcccggca atcatctacg gtggcaaaga agcgccgctg gctatcgagc
    53281 tggatcacga caaagtcatg aacatgcaag ctaaagctga attctacagc gaagttctga
    53341 ccatcgttgt tgacggtaaa gaaatcaaag ttaaagctca ggacgtacag cgtcacccgt
    53401 acaaaccgaa gctgcagcac atcgacttcg ttcgcgctta attgctgaat aagttgtaaa
    53461 aaaccccgct ccggcggggt tttttgtatc tgcagattat gcctgattac ggtattgcta
    53521 ttttttgcag gccagataag gcgttcacgc cgcatctggc attcagaaca caaaaccgat
    53581 taattgccgc cagacgtccg gcgctgcaat tggtcgcgca aattcggcgg cgtgccttta
    53641 atggtcaagg tatcggttgc tggatcccag aagatgcgtt cacctaacag catcgcatca
    53701 aagttaatag tcaagccacc gccgctaccg gcaaacttcg tcaactgacg cagtgtgcta
    53761 cggtctgccg ggaagctctc ttccagttcg tagccttttt cagccgcaaa ctccgtgaag
    53821 ctcacttcgc ttacgcctgc cagctctttc gacagcgatt tcagttcgat ctcttcgcct
    53881 gcctgcagct gctcattaca gtagctataa acctgctggc gcacgttctg tcgctctgct
    53941 ttatccagtt gtgcttcggc agtgaaatca tcaaccgctt gcaacagccc acggttttgc
    54001 gctttcgcgt ttaacccttc gctggccccg aggaaatcca taaagaaatc cgccactttg
    54061 cgccctactc gccctttcag gaaagtgaga tagcgggtgg actctggatt ggtttcccat
    54121 tcggttaaat cgatacgcgc aacaatatcc gcatgattga tatcaagata atgggttggg
    54181 ttgatgtcga gattttcgtt aacgcgcata ctgctcaggt tgctcagaac tgccaccagc
    54241 aaatactcca ccgccagata gcgatagtgg caaaacagca cgaatccacc gtcagcaaaa
    54301 ggatatttcg ctaattcgtc acgcaggcgg ccggttgccg cgcggctaaa tgccaggaag
    54361 tcctcttcgc cctgacgctg taagcgcagc gtctgcgcca gttcactctc ttcgctaaac
    54421 aagccgtaag ctttattttt ggcgctatag acccgatgca gttctgccac catctcaacg
    54481 acggtttctg tcggttccag caatgaatcg cgcaacacca gctcaaggtt ctgctcatca
    54541 cgcttgataa gctggtgcag agcaatctgg ttgatatcca gactcatgat aaactctcct
    54601 ttaagaccgg gcggtattca accaccgccg gttaagcgac gcaataaaag atggcggtca
    54661 ttttacagaa ggcagcgtaa cgagaatgat ttaacgcata aaaaagcaga aaaaaaaccg
    54721 ttgctacggt aatatgttgc cctttcatca actaactgat ttcgatttat gccacaaatt
    54781 tcccgctaca gtgatgaaca ggttgaacaa ttgctcgcag agctgctcaa cgtactggaa
    54841 aaacataagg ctccgaccga cctttccctg atggtgttag gcaacatggt cactaacctt
    54901 atcaacacca gcattgcccc ggcccaacgc caggcaattg ccaactcttt tgcccgcgcc
    54961 ttacagtcct ctatcaacga agacaaagcg cactaaggga aacagataac aggttatggt
    55021 aactcatcgt cagcgctacc gtgaaaaagt ctcccagatg gtcagttggg ggcactggtt
    55081 tgcactgttc aatattctgc tttcgctcgt cattggcagc cgttacctgt ttatcgccga
    55141 ctggccgaca acgcttgctg gtcgcattta ttcctacgta agcattatcg gccatttcag
    55201 cttcctggtg ttcgccacct acttgctgat cctcttcccg ctgaccttta tcgtcggctc
    55261 ccagaggctg atgaggtttt tgtccgtcat tctggcaacg gcgggaatga cgctattact
    55321 gatcgatagc gaagtcttta ctcgtttcca tctccatctt aatcccatcg tctggcaact
    55381 ggttatcaac ccagacgaaa atgagatggc gcgcgactgg cagctgatgt tcatcagcgt
    55441 gccggttatt ttattgcttg aactggtgtt tgcgacgtgg agctggcaaa agctgcgcag
    55501 cctgacgcgt cgtcgacgct tcgcgcgccc gctggccgca ttcttattta tcgcctttat
    55561 cgcctcgcat gtggtgtata tctgggccga tgccaacttc tatcgcccga tcaccatgca
    55621 gcgcgctaac ctgccgcttt cgtacccgat gacggcgcga cgttttcttg agaagcatgg
    55681 tctgcttgat gcgcaggagt atcaacgccg tcttattgag caaggtaatc cagacgccgt
    55741 ttccgttcag tatccgttaa gcgaactgcg ctatcgcgat atgggcaccg ggcagaatgt
    55801 gctgttgatt actgtcgatg gcctgaacta ctcacgcttc gagaagcaga tgcctgcgct
    55861 ggcaggtttt gctgagcaaa atatttcgtt cacgcgccat atgagctccg gcaacactac
    55921 agacaacggc atctttggcc tgttctatgg catctcgccg agctatatgg acggcattct
    55981 gtcgacccgt acgcctgcgg cattaattac tgcgcttaat cagcaaggct atcagctggg
    56041 gttattctca tcagatggct ttaccagccc gctgtatcgc caggcattgt tgtcagattt
    56101 ctcgatgccg agcgtacgca cccaatccga cgagcagacc gccacgcagt ggatcaactg
    56161 gctgggacgc tacgcacaag aagataaccg ctggttctcg tgggtttctt tcaatggtac
    56221 taacattgac gacagcaatc agcaggcatt tgcacggaaa tatagccggg cggcaggcaa
    56281 tgtcgatgac cagatcaacc gcgtgctcaa tgcactgcgt gattctggca aactggacaa
    56341 tacggtggtg attatcactg ccggtcgggg tattccactg agcgaagagg aagaaacctt
    56401 tgactggtcc cacggtcatc tgcaggtgcc attagtgatt cactggccag gcacgccggc
    56461 gcagcgtatt aatgctctga ctgatcatac cgatctgatg acgacgctga tgcaacgcct
    56521 gctacatgtc agcacacctg ccagcgaata ttcgcaaggt caggatttgt tcaaccctca
    56581 acgccgtcat tactgggtta ccgcagcgga taacgatacg ctggcaatta ccaccccgaa
    56641 aaagacgctg gtactgaaca ataacggtaa ataccgcact tacaacttac gtggtgaaag
    56701 agtgaaagat gaaaaaccac agttaagttt gttattgcaa gtgctgacag acgagaagcg
    56761 ttttatcgct aactgattaa ttataaatca gttagcgaaa tatcttactt gcaatcggtg
    56821 tggaaaacgg tagtattagc agccacgagt cggcacgtag cgcagcctgg tagcgcaccg
    56881 tcatggggtg tcgggggtcg gaggttcaaa tcctctcgtg ccgaccaaat cgaatatcgg
    56941 acagcatcgg taacctattg aaagcccgtt aatttactga ttaacgggct tttttgttgt
    57001 tttcagtcgc cggattgaat cggtaagata gggttgtaac cggatttttt agctacacgt
    57061 ttagctatac ggtccagcgt gtagctaaag ccgtatagct acgaccaggc atatagctac
    57121 cgatgagtaa aaaaacatgg cacgaaaaac caccccacta actattacgg agatcaaaaa
    57181 cgcacgacca ggggaaaagg aatataccct gcaggatggc ggaggattat ttcttctggt
    57241 gaagccctcc ggatcaaaaa tctggcgttt tacgtactac cgcccggcag ataaaaaacg
    57301 gactattatc agccttggat cgctaaatga tgtttccctg tctgatgcca gagagcgacg
    57361 gaatgaatac aggtcactca tagcaaaggg aactgaccca caggactacg aacgccggaa
    57421 acgtgaagca gagagcagta aaaagggcaa cacgttcgaa aaagttgcct tggactggta
    57481 cgagatgaaa aaaggccaga atctggctta caacacgatt aaggatatct ggcgatccct
    57541 ggaaaaatac gtattcccgt acatcggaaa cacgccaata gataccctca ccgctcgccg
    57601 ctttgttgag atactcacac ccattaaagc acgcggcaac ctagaaactc tgaaacgcgt
    57661 tttacaacgc atcaatgaag tgatggattt tgctgccaac agtgggctga ttgacatcaa
    57721 caccgccgcg aacgtccgca aggcattccc ttcccccact aaaaagcata tgccaaccat
    57781 ccgaccggaa cagctaccgc agctaatgca cgatttatcg gtcgccagca tagaacggca
    57841 aaccagattg ctaatcgagt ggcaactgct gaccgtagca cgcccagccg aagcagccgc
    57901 cgcacgctgg gaagaaatag atctcgatgc cgaaacatgg acgattccag ccggacgcat
    57961 gaagatgcgc cgtgaccatg tgatccctct ttgcggtcag gcgatggctg tactggaaac
    58021 aatgaagcca atcagcgcac acagggaaca tgtttttccc agccttaaaa atccaatgct
    58081 gccaatgagc agccagaccg ctaacgctgc attgcgccgg atgggatacg ctggtgtgct
    58141 ggtgtctcac ggattacgcg ccatattcag tacagcagcg aacgaggaag gattcgagcc
    58201 ggacgtaatc gaggccgcac tcgcacacgt ggacacgaac gaggtaaggc gagcatataa
    58261 ccgaagtaac tacctggaaa agcgcgtggt gcttatgcgc tggtgggggg aatttgtaga
    58321 ggccgcagct accggagtga ccatagccag tggtaaaagg ggtatccgtg ccgtgtaact
    58381 gtacaaaaaa ccagtaaaag cgatgcaaac catgctaaac catcgtataa tcgccacaac
    58441 ccacccaata cagagaggag tcacccaaat catgaaattc aaggagctat ccaggtgttt
    58501 ttcaatgaaa aggtatcccc tgcttgcggc gaagggctgc aactggcgtt aatggcaaat
    58561 cgtgaattct ggtcaacata cgatccggaa gacaaatcaa cagcccccac aaaacacgag
    58621 gtagtcagtt ttttgcgctc gcgtggtgca tcaaaaaatc tggctgaaag catcgacaag
    58681 gtgctgaggc ccaccagcct taaatgcggt gggcgaccta agaagtggaa acggtaatca
    58741 caatagcggc cctttgcggt cgctattttt ttgcagaaag aaaagcgtaa tcaatgagat
    58801 aaaaaacagt ggataccgtt ttaaaacggt gggtactgtt tttcccgccc tgccctgttt
    58861 taccgtattt atcaccggaa tacgccggat taacgaggta aaacatagtg gaaacaatca
    58921 gaaaaatact tacccgtcag gaagtaaaaa atattctgcg catcaaggca gacagttcgc
    58981 tacaggacat gatcaacgcc ggaaaattcc cgaaaggctt caaaatcggt ctgcgtcgtg
    59041 ttggctggta tgaagatgaa gtgctggcct ggctgaaaga gcgcgaggaa gaagcgcgcg
    59101 gaacggctgc gtaatggtgt gaggcgtaac gtgatgaaca taacaaaaag cgccccgttg
    59161 ccggagcgcc cttgcgaaca attaacctac tgcgcaaaaa atgaatcagt gcagtgggat
    59221 tatatcaacc gtgtagcgaa gcgccacaat tgccggataa caggcaaaac aaaggccacc
    59281 cgctacggtg gcccttcgac acaagctaca cgttatcccc aacgcatgag cattgccaac
    59341 aatgccacat ttgcggctgg tgggcaatgt gatcagtgtg ctggcttgct ggtgggctat
    59401 tcctgctctt taacattgcc atgccgcgat gttttccagg tatgcgaccc catttttgtg
    59461 cgcctgtact cttttaagaa cttctcaagg gcaaacgcac atggcgcaaa tctctcctgt
    59521 tcttgttcgc ttaccgcatt tttgcgttgt tttttcctgg atgaggataa tttctttaat
    59581 gatttgtcag tcatcgtaga tacctgtaac ccagtgcgcc acagttcacc gcaccacagc
    59641 gctggtgatg gttactcctg ctctttggcc ttgcgccgct ggcggcgttt gatctcgcct
    59701 tgcattgacg taatgatgaa ttgtgatgtg ctttcgcctg attctttcac tgattccatg
    59761 gcgtttacta tttcgtgtgg tacacgagcc tttagagctt gtgattttgc gtttgttgta
    59821 cccgttgcca tttctattcc tctggtggat tggtggggga cagtatacac agaaaaagca
    59881 caaataaaac tcttgacgtg ggccacacct aaaacatata gtgggccaca ccttaaaatt
    59941 atcaaggcgc ataaatgcaa agccccgcaa gtgtcgttac cactcgcagg gcttctaacc
    60001 accaacgata gcagaagtat cgaggtagct atgttaaatc ataccacaca cccgcaaggg
    60061 cgggactcgc acaacctgaa taaatacatc tggcgtttta tcgccctgag cgcggcacaa
    60121 ccgcgcgtga ttaccattga ggccaccaac gaacaggaag cgcgtcagca atctcctgat
    60181 ggctgcgtga tggtattcgc cgcccgtatt cgtcaggagg tgcgccatgt gcaataacac
    60241 ccgtcaggac gcagccgccg aagccatcaa aacgctgatg cacgcgctga ttgatatttc
    60301 tgttatcgcg gacagggcac ataagcacgc caccagcgaa acagaatatg ccggggcttt
    60361 cgttcctcac tcactggctg ttatgcaatt tagtgctgat atggcactga atgaggctaa
    60421 agccatcctg attactgatt gtgaaaatgg gggggttatg cgtgatgatc gttttaatgc
    60481 cctgaaacag gaattttccg gcgttcctgg tgatgcggct gatgcgcttt cgtcaatgcc
    60541 agaacttatt agagcggatt ttttcttact ttccacgaaa gaatataaat caacgggact
    60601 tgatgtactg aatattgccg ccgattatgc tgatttcgtg acagaggtta ttttaagaaa
    60661 agcgacggac ggggattaat atgcgtgata tttaccacga aacaatagac cgcgcatttc
    60721 ttgcactttc tcacagtgaa aacatgttgg aaatattgcg cttatggctt gaaacgcttg
    60781 gcgataatga acgcgacaaa caaaaatccc gaattgtcac ggcattaata acgcttcttg
    60841 agcctgtaat aatggaacta caagaaatag acctattgca cgacagatat aaagaacagc
    60901 acaccggaga ataaaaataa tgaaactaaa atatcctggc ttaactgcca gcggaaaaac
    60961 tcgcactaaa ttcatgcgcg gtgatattta ccgcgaccag tacggcggca cggtaatgat
    61021 taagggcgtg gaggaacggc gcgtaactta ccgccgtgaa ggttacgaat atgattgcgt
    61081 gatgcctgtt tatcagtttg cccgtgattt ctctctggta cagaccgcgc cgcataacgt
    61141 gcccaccagc aacgccaggg cacgggcaaa catccagaag ctgaaaacca tgattaacgc
    61201 attcaggggt aaaaaatgaa actggcaccg aacttaaaaa aacagccaca cgacaaaatg
    61261 accgaagtca ttatttttgc gggtagtgat gcctgggcgc acgcgaaaca atggcaggaa
    61321 caggacgggc gacttgctgg cgacaacgtg ccacctgtat ggcttggaga cagccagctt
    61381 gacgaactgg cagacctgaa aattatcgac gatggtcgct attgtgtccg gctgtacaag
    61441 gcaggccaca tcaagccgtc aaatattaat gccatcgggc aaaagctggc ggtggcaggt
    61501 gtacgggatg cgaattatta ccctgaggga atgcacagcc agaagcggga gaactggcac
    61561 gaatatctgg agcgtgagcg ccagaatctt tctgatggtc tggttattca gcttcctgtt
    61621 aagaaaaaaa cagaagacag cgccgcacca ctggcgctta accagatggg agcaagccag
    61681 cgcggcgaag ttctcctggc acgttatggc ggtgaactgg caatcaatgc ggactctgac
    61741 accgttcacc actacaacgg cgttgtatgg gagccggtac aggataaaga gttacagcgg
    61801 gctatggcgc agatttttat tgatgcggag atcagttatt cgcagaacgc catcaaatcg
    61861 gcggtcgata ccatgaagtt aagtttgccc gtaatgggga ataccgcccg taacctgatt
    61921 ggattcagta acggtgtttt tgatacccgg acaggcgatt ttcgggagca tgacaaaaac
    61981 gactggctgt taattgccag tgaattaccg ttcagcccgc cagcagaggg ggaaacgctg
    62041 gcaacgcatg cgccgaattt ctggaaatgg ttgcgccgtt cggtggcaga gaatgaccgt
    62101 aaagcggatc gcgtactggc ggcgttattc atggtgctgg cgaaccgata cgactggcag
    62161 ttatttcttg aggtaacggg gccgggtgga agcggtaaaa gcgtaatggc agagatttgc
    62221 accatgctgg cgggtaaggc caacacggta tcggcaagca tgaaggcgct ggaagatgcc
    62281 agggaacgcg cgttagtggt tggcttttcg ctgattatca tgccggatat gacccgctac
    62341 gctggtgatg gcgcaggaat taaggccatt acaggcggtg acaaggtggc aatcgacccg
    62401 aagcataaag ccccctactc aacacgcatt caggcggtcg tgctggcggt gaacaataac
    62461 gccatgtcat tcagtgaccg cagcgggggg atctcacgtc gtcgggtgat attcaatttt
    62521 tcggaggttg taccggaaaa cgaacgcgac cccatgctgg cagaaaaaat agaaggagag
    62581 ctggcggttg tgattcgtca cctgcttact cgtttttctg accaggacga agctaaacgc
    62641 ctgctgtatg agcagcagaa atcagaagaa gctctggtga taaaacgcga gggcgattcg
    62701 ctggtggact tctgcggcta tctcatgtcg tcggtaatgt gtgatggtct gttagtgggt
    62761 aatgccgaaa ttattccgtt cagtccgcgc aggtatcttt atcacgccta tctggcatat
    62821 atgagggcac acggattcgg taaacctgta acactgacgc gcttcggtaa agatatgccg
    62881 ggggcaatgg cggaatatgg cagggagtat atgaaacgga aaacgaagca cggtttgcgt
    62941 tcaaatgtga cccttacaga ggattcagaa gactggatgc catcatgtgc atcggtcaca
    63001 aatgacgatg gaaaaaatta aacttatgga ataactgttc accactgttc accatatcat
    63061 aaatgtcttt tatatcagta tattataggg tgaacagtta tttatgaact gttcaccaaa
    63121 ctattcactg ttcacctttt tgattgttta ttgagcttaa gggtgaacag tggtgaacag
    63181 ttggtgaata gtttttgtga aactgttcac cccttaacac catgaataaa aagggaaaat
    63241 ctcaaaaggt gaacaggtga agggttaaaa tgcaaaaatt ttattttatt gctgtgaggt
    63301 aaagcctgtg acaacgaagc acgcaaaaaa accacaatct cacgcccttg atttgacaga
    63361 acactggctg agggtggcga taaaaatcat cgatcgcaac gcgggagaag gatacgcgaa
    63421 agcacatcct gaactgataa gcgcattcat gacaacggcg gcggcaaact ttgccacgct
    63481 gacagaacgg gagattgccg aagcggaaca ggtgacaacc atcaatgtta aaaccggaga
    63541 ggtggaatca tgacagcaca gatagcggct tacgggcggc tggtggctga cccgcagtta
    63601 aagaccacca gcaagggcac acaaatggcg atggcgagta tggcggttcc cctgccgtgc
    63661 agccaggcag atgacggaac ggcgacgatg tggttatccg tcctggcgtt tggcagacag
    63721 gccgacgcac tggcaaagca ccagaaaggc gaactggtga gcgtggcggg taacatgcag
    63781 ataagccagt ggacaggcca gaacggcgaa acgcggcagg gctggcaggt tatcgcagac
    63841 agtgtaatca gtgcccgaac ggcgcgaccg ggcggcaaaa aaggccagca gggccaggct
    63901 actgacgcgc tgaacagagc aaaacaacag gcgggaaatg atgatccgta cggggataac
    63961 ataccgtttt aagcaacgag tgacagaagc cggaacaatc cggctttttt acgggtcctc
    64021 ccgatggagt ggccttgcca cggggcggga gcggcgcgga aaaaggctgg tttttgcatt
    64081 ttcatggcgg cggcagcatg tgtgataatt tattgataat taaaaaatat ttccgttttc
    64141 acctgtacaa ta
//
LOCUS       DAPHKZ010000013        63340 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.013, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000013 DAPHKZ010000000
VERSION     DAPHKZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 63340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63340
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.013"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            27..728
                     /locus_tag="RH288_000855"
     CDS             27..728
                     /locus_tag="RH288_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV4029945.1"
                     /translation="MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEG
                     EEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGA
                     PLAKDRETLFFTSVRAVPSTTKRKEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLR
                     CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRT
                     INDYGAETPQLNCKS"
     gene            753..3353
                     /locus_tag="RH288_000856"
     CDS             753..3353
                     /locus_tag="RH288_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HDV4029946.1"
                     /translation="MYRTHRQHSLLSSGGVPSFIGGLVVFVSAAFNAQAETWFDPAFF
                     KDDPSMVADLSRFEKGQKITPGVYRVDIVLNQTIVDTRNVNFVEITPEKGIAACLTTE
                     SLDAMGVNTDAFPAFKQLDKQACVPLAEIIPDASVTFNVNKLRLEISVPQIAIKSNAR
                     GYVPPERWDEGINALLLGYSFSGANSIHSSADSDSSDSYFLNLNSGVNLGPWRLRNNS
                     TWSRSSGQTAEWKNLSSYLQRAVIPLKGELTVGDDYTAGDFFDSVSFRGVQLASDDNM
                     LPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQTYVSPGAFEISDLYSTSSSGDLLVE
                     IKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAKYRTNSNEQQESKFAQATLQWGGP
                     WGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDATQAKSTLADQSEHKGQSYRFLY
                     AKTLNHLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGYEFNDGDDEDTPMWSRYYNLFY
                     TKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLLQFGYNTQIKDLSLGISWNY
                     SKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWMTSNTSIDNEGHTTQNLG
                     LTETLLDDGNLSYSVQQGYNSEGKTANGSASMDYKGAFADARVGYNYSDNGSQQQLNY
                     ALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGLKTDWRGYTVVPYATSY
                     RENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGARVLMKTSKQGIPLRF
                     GAIATLDGVQANSGIIDDDGSLYMAGLPAKGTISVRWGEAPDQICHINYELTEQQINS
                     AITRMDAICR"
     gene            3344..4415
                     /locus_tag="RH288_000857"
                     /pseudo
     CDS             3344..4415
                     /locus_tag="RH288_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415461.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
     gene            4427..4969
                     /locus_tag="RH288_000858"
     CDS             4427..4969
                     /locus_tag="RH288_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4029947.1"
                     /translation="MKKKTIFQCVILFFSILNIHVGMAGPEQVSMHIYGNVVDQGCDV
                     ATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAP
                     TLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKST
                     KAGATGGNATAVLYFDLVYQ"
     gene            4977..5492
                     /locus_tag="RH288_000859"
     CDS             4977..5492
                     /locus_tag="RH288_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4029948.1"
                     /translation="MLKRIIWILFLLGLTWGCELFAHDGTVNISGSFRRNTCVLAQDS
                     KQINVQLGDVSLTRFSHGNYGPEKSFIINLQDCGTDVSTVDVTFSGTPDGVQSEMLSI
                     ESGTDAASGLAIAILDDAKILIPLNQASKDYSLHSGKVPLTFYAQLRPVNSDVQSGKV
                     NASATFVLHYD"
     gene            5458..6195
                     /locus_tag="RH288_000860"
     CDS             5458..6195
                     /locus_tag="RH288_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HDV4029949.1"
                     /translation="MPARHLYFIMTNTWNRLALLIFAVLSLLVAGELQAGVVVGGTRF
                     IFPADRESISILLTNTSQESWLINSKINRPTRWAGGEASTVPAPLLAAPPLILLKPGT
                     TGTLRLLRTESDILPVDRETLFELSIASVPSGKVENQSVKVAMRSVFKLFWRPEGLPG
                     DPLEAYQQLRWTRNSQGVQLTNPTPYYINLIQVSVNGKALSNVGVVPPKSQRQTSWCQ
                     AIAPCHVAWRAINDYGGLSAKKEQNLP"
     gene            6306..7316
                     /gene="pyrD"
                     /locus_tag="RH288_000861"
     CDS             6306..7316
                     /gene="pyrD"
                     /locus_tag="RH288_000861"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HDV4029950.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPA
                     KPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICME
                     KIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKI
                     APDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKST
                     EIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            7490..8032
                     /gene="zapC"
                     /locus_tag="RH288_000862"
     CDS             7490..8032
                     /gene="zapC"
                     /locus_tag="RH288_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415466.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HDV4029951.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAF
                     SPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHG
                     EMWVPMPGDAACVWLSDTHEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
                     MNDRLKPQVNVDSFSLEQAV"
     gene            complement(8029..9138)
                     /gene="ycbX"
                     /locus_tag="RH288_000863"
     CDS             complement(8029..9138)
                     /gene="ycbX"
                     /locus_tag="RH288_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein YcbX"
                     /protein_id="HDV4029952.1"
                     /translation="MATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGT
                     FITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIA
                     PDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQ
                     RCPASVKMEQFRPNLVVSGASAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQ
                     KHPAGEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAA
                     ADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQ
                     LLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR"
     gene            9382..11490
                     /gene="rlmKL"
                     /locus_tag="RH288_000864"
     CDS             9382..11490
                     /gene="rlmKL"
                     /locus_tag="RH288_000864"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HDV4029953.1"
                     /translation="MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLV
                     YQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLH
                     LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGL
                     HRGRWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNAR
                     LAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMK
                     NQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVA
                     EDYTNRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTI
                     DAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNA
                     HLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTT
                     VDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKR
                     MEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKT
                     LSQDFARNRQIHNCWLITAA"
     gene            11502..13409
                     /locus_tag="RH288_000865"
     CDS             11502..13409
                     /locus_tag="RH288_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4029954.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYH
                     DISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVFEMEDVCYQVNGKQL
                     VKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKTEEAAAAKAETVKRSSSKLSYKL
                     QRELEQLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFER
                     WEYLEALKNGG"
     gene            13539..14792
                     /gene="pqiA"
                     /locus_tag="RH288_000866"
     CDS             13539..14792
                     /gene="pqiA"
                     /locus_tag="RH288_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HDV4029955.1"
                     /translation="MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTF
                     FLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
                     KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIR
                     QGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIM
                     VTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDRQPESEHEES"
     gene            14797..16437
                     /gene="pqiB"
                     /locus_tag="RH288_000867"
     CDS             14797..16437
                     /gene="pqiB"
                     /locus_tag="RH288_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HDV4029956.1"
                     /translation="MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPE
                     VTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDT
                     VFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRV
                     ILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTNNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGLPVAPKTAFVLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYR
                     IPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNT
                     PAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRT
                     MKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            16434..16997
                     /gene="pqiC"
                     /locus_tag="RH288_000868"
     CDS             16434..16997
                     /gene="pqiC"
                     /locus_tag="RH288_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HDV4029957.1"
                     /translation="MKKWLVTIAALWLAGCSSGEINKNYYQLPVVQSGTQSTASQGNR
                     LLWVEQVTVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGW
                     VVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDG
                     YDEMVKVLAGVWSQEAASIAQEIKRLP"
     gene            17253..17420
                     /gene="rmf"
                     /locus_tag="RH288_000869"
     CDS             17253..17420
                     /gene="rmf"
                     /locus_tag="RH288_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HDV4029958.1"
                     /translation="MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGW
                     REAMADRVVMA"
     gene            complement(17490..18008)
                     /gene="fabA"
                     /locus_tag="RH288_000870"
     CDS             complement(17490..18008)
                     /gene="fabA"
                     /locus_tag="RH288_000870"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HDV4029959.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASD
                     LKVGLFQDTSAF"
     gene            complement(18077..19837)
                     /locus_tag="RH288_000871"
     CDS             complement(18077..19837)
                     /locus_tag="RH288_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HDV4029960.1"
                     /translation="MTITKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQF
                     ALEQLLHTRASSSFMLAKAPEESEYLNLIANAARTLQSDAGQLVGGHYEVSGHSIRLR
                     HAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRT
                     LLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELSEQAIYSEFEDTLQIVDAESVTQWCRWVTFTARHNHLPAPGADAWPILIREAA
                     RYTGEQETLPLSPQWILRQCKEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDE
                     ILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVR
                     HLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQ
                     QEGRHRFPWPLRWLNWFIPN"
     gene            20023..20475
                     /gene="matP"
                     /locus_tag="RH288_000872"
     CDS             20023..20475
                     /gene="matP"
                     /locus_tag="RH288_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HDV4029961.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVL
                     LSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE"
     gene            complement(20551..21591)
                     /gene="ompA"
                     /locus_tag="RH288_000873"
     CDS             complement(20551..21591)
                     /gene="ompA"
                     /locus_tag="RH288_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HDV4029962.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGF
                     INNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTA
                     KLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRL
                     EYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLK
                     SDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER
                     RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV
                     KGIKDVVTQPQA"
     gene            complement(21948..22457)
                     /gene="sulA"
                     /locus_tag="RH288_000874"
     CDS             complement(21948..22457)
                     /gene="sulA"
                     /locus_tag="RH288_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HDV4029963.1"
                     /translation="MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPM
                     MTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVES
                     MVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
                     LKIHSNLYH"
     gene            22676..23305
                     /gene="sxy"
                     /locus_tag="RH288_000875"
     CDS             22676..23305
                     /gene="sxy"
                     /locus_tag="RH288_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRP-S regulon transcriptional coactivator Sxy"
                     /protein_id="HDV4029964.1"
                     /translation="MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVS
                     DGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYS
                     LDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
                     SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE"
     gene            complement(23268..25430)
                     /gene="yccS"
                     /locus_tag="RH288_000876"
     CDS             complement(23268..25430)
                     /gene="yccS"
                     /locus_tag="RH288_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309071.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HDV4029965.1"
                     /translation="MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLT
                     IPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIASASVELLFPWPWLFAIGLTLST
                     SGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
                     HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDQSQAPLYDLALANGLLMATLN
                     QTKLSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFR
                     FQRLMSMQGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTL
                     GFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESA
                     LFRHAVRMSLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLV
                     GIAIGIPVLWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEG
                     FEVALPRVIDTLIGCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAILEQYHQ
                     GRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYIS
                     ALGAHREQLTNPEILAFLDDAVCYVDDALHHQPADEERVNEALASLKQRMQQLEPRAD
                     SKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA"
     gene            complement(25440..25886)
                     /locus_tag="RH288_000877"
     CDS             complement(25440..25886)
                     /locus_tag="RH288_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDV4029966.1"
                     /translation="MRTVLNILNFVLGGFATTLGWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQC
                     ISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE"
     gene            26009..28063
                     /gene="helD"
                     /locus_tag="RH288_000878"
     CDS             26009..28063
                     /gene="helD"
                     /locus_tag="RH288_000878"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HDV4029967.1"
                     /translation="MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDAHWRRWSGEMSEIASGV
                     LRQQLDLIATRTGENKWLTREQTSGVQQQIRQALSALPLPVNRLEEFDNCREAWRKCQ
                     AWLKDIESARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGA
                     GSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFH
                     ALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQ
                     WSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLM
                     APLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL
                     AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGERCDLDTTYRFNSRI
                     GEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDESQLDALLDKLSGYAKPEERILIL
                     ARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARES
                     IMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVAR
                     KP"
     gene            complement(28095..28553)
                     /gene="mgsA"
                     /locus_tag="RH288_000879"
     CDS             complement(28095..28553)
                     /gene="mgsA"
                     /locus_tag="RH288_000879"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDV4029968.1"
                     /translation="MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYA
                     TGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK"
     gene            complement(28649..29311)
                     /locus_tag="RH288_000880"
     CDS             complement(28649..29311)
                     /locus_tag="RH288_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HDV4029969.1"
                     /translation="MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLL
                     RGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLE
                     NEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASL
                     PQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQP
                     SS"
     gene            29484..29897
                     /locus_tag="RH288_000881"
     CDS             29484..29897
                     /locus_tag="RH288_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDV4029970.1"
                     /translation="MKETDIAGILTSTHTIALVGASDKPDRPSYRVMKYLLDQGYHVI
                     PVSPKVAGKTLLGQKGYGTLADVPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWMQL
                     GVINEQAAVLARDAGLNVVMDRCPAIEIPRLGLAK"
     gene            complement(29942..30259)
                     /gene="hspQ"
                     /locus_tag="RH288_000882"
     CDS             complement(29942..30259)
                     /gene="hspQ"
                     /locus_tag="RH288_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HDV4029971.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVND
                     ELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPR
                     LRN"
     gene            complement(30317..31507)
                     /gene="rlmI"
                     /locus_tag="RH288_000883"
     CDS             complement(30317..31507)
                     /gene="rlmI"
                     /locus_tag="RH288_000883"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HDV4029972.1"
                     /translation="MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVD
                     HQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFSRRLQQAQKWRDWLAQKDGLDSY
                     RLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECSIYDRSDVA
                     VRKKEGMELTQGPVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRY
                     VENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFV
                     RDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGI
                     LLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFA
                     CRVM"
     gene            31602..31880
                     /gene="yccX"
                     /locus_tag="RH288_000884"
     CDS             31602..31880
                     /gene="yccX"
                     /locus_tag="RH288_000884"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDV4029973.1"
                     /translation="MSKVCIIAWVYGRVQGVGFRYTTQYEAKRLGLTGYAKNLDDGSV
                     EVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR"
     gene            complement(31877..32206)
                     /gene="tusE"
                     /locus_tag="RH288_000885"
     CDS             complement(31877..32206)
                     /gene="tusE"
                     /locus_tag="RH288_000885"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HDV4029974.1"
                     /translation="MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHW
                     EVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(32297..32956)
                     /gene="yccA"
                     /locus_tag="RH288_000886"
     CDS             complement(32297..32956)
                     /gene="yccA"
                     /locus_tag="RH288_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HDV4029975.1"
                     /translation="MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGM
                     GDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            complement(33364..34383)
                     /locus_tag="RH288_000887"
     CDS             complement(33364..34383)
                     /locus_tag="RH288_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV4029976.1"
                     /translation="MGRPRKNKKDNALPPRVRSNGYSYVWKPKGSTRTIGLGRVRETS
                     VAKVWQNYELEKAKLHNIMTVAKLWHMFMDSPAFTELAPRTQKDYRQHQRALLAVFGK
                     VLADNVKIEQVRIFMDKRGLESKTQANHELASLSRVYGWGYERGYVKNNPCKGVRKFT
                     LKARTVYITDEQYAAIYAEAIPQLRIAMEISYLCAARLGDVLELKWQDIMEKGIYIEQ
                     NKTGTKQIKEWSPRLRTAIQLARNVSSGTCEYVINTTKGGKVIAKTLNNWWNQAKRAA
                     EQKAGVPFGCNFHDIKAKGISDYEGSSRDKQIFSGHKTENQVLIYDRKTKITPTLDLP
                     LVVSK"
     gene            complement(34352..34603)
                     /locus_tag="RH288_000888"
     CDS             complement(34352..34603)
                     /locus_tag="RH288_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4224 domain-containing protein"
                     /protein_id="HDV4029977.1"
                     /translation="MYELTLSPAEIQEITKYERYTKQQHQLRLHGIPFVIGPKNEPIV
                     LRRDIPHGLTTMPKAPELVSAEPDFEALNNGKTKKKQKR"
     gene            complement(34670..37141)
                     /locus_tag="RH288_000889"
     CDS             complement(34670..37141)
                     /locus_tag="RH288_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HDV4029978.1"
                     /translation="MSKVFICAAIPDEQAIKEEGAVAVATAIEAGDERRARAKFTWQF
                     LEQYPAAQDCAYKFLVCEDKPGMPRPAIDSWDTEYMQENCWDEESASFIPIEPESDPM
                     NVNFDKLSPEVQNAVLVKFDTCENITVDMVISAQELLQEDMATFDGHIVEALMKMPEV
                     NAMYPELKLHAIGWVKHKCIPGAKWPEIQAEMRIWKKRREGERKETGKYTSVVDLARA
                     RANQQYTDNSTGKISPVIAATHREYKQTWKTLDDELAYALWPGDVDAGNIDGSIHRWA
                     KNEVIDNDREDWKRISASMRKQPDALRYDRQTIFGLVRERPIDIHKDPVALNKYITEY
                     LTTKGVFEDEGRNQSATDTLSSPVPETDAVETAIPDNEKTECKVEVEPSVEREGPFYF
                     LFTDKDGEKYGRANKLSGLNKALTAGATEITKEEYFARKNGTYSGSQQNTGASDTTAQ
                     PEPVKVTADEVNKIMQAANITQPDADKLLAVSRGEFVAGISDPNDPKWVKGIETRDSV
                     NQNQQETEQNDQKAEQNSPNALQNEPETKQPEPVAQQEAEKVCTACGQTGGGNCPDCG
                     AVMGDATYQETFDDKNQVEVQEDDSEKMEGAEHPHKENAGSAQDHASDSETGETADPL
                     ITVNGHHVITSTSRTCDHLMIDLETMGKNPDAPIISIGAIFFDPQTGDMGPEFSKTID
                     LETAGGVIDRDTIKWWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVQVWG
                     NGANFDNTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERHNA
                     LDDARYQAKYVSAIWQKLIPNPVDF"
     gene            complement(37222..37425)
                     /locus_tag="RH288_000890"
     CDS             complement(37222..37425)
                     /locus_tag="RH288_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HDV4029979.1"
                     /translation="MNTVFALVLTVFLNTGEPVDLVIGIHDSMKECMAAAAEQKIPGN
                     CYPVDKVIRMDNNEIPAGLKTAP"
     gene            complement(37428..37610)
                     /locus_tag="RH288_000891"
     CDS             complement(37428..37610)
                     /locus_tag="RH288_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HDV4029980.1"
                     /translation="METLLPNVNTSEGCFEIGVRISNPVFTEDAINKRKHERELLNQI
                     CIVSMLARLRLMQKGR"
     gene            complement(38356..38745)
                     /locus_tag="RH288_000892"
     CDS             complement(38356..38745)
                     /locus_tag="RH288_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029981.1"
                     /translation="MEFKELPKEIQEIAAHTLRQRLNEVALEAETKKDIDNMARNVRD
                     AFTGLYSVSVEDNNIPDEQEESTDPHKFWKSVEVIAKAKLLELNNLYHRENDGRQSLH
                     HQGVATLIALTKEQGEYHPVALNDTVK"
     gene            complement(38757..38909)
                     /locus_tag="RH288_000893"
     CDS             complement(38757..38909)
                     /locus_tag="RH288_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HDV4029982.1"
                     /translation="MDTIDLGNSESLVCGVFPNQDGTFTAITYTKSKTFKTETGAHRW
                     LARNTD"
     gene            complement(39183..39827)
                     /locus_tag="RH288_000894"
     CDS             complement(39183..39827)
                     /locus_tag="RH288_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HDV4029983.1"
                     /translation="MESLGIRLKRLRKDKGLTQVELGKLSGVTGVTIGYWEKDLNEPG
                     SKALSKLAQALGTTESYLLYGVSSTEPTLVQNNSGTQIPYLSWGEAISFLILEGEKTM
                     GNADRITTFFDVKEGDFAVSMPDDTMHNPSGSPSIPVGATVIMRPREKYKNGSIVAVI
                     VPDPLTNEPSMTIKKLVIDGKLVYLSPLNPRYQSSLLTPECKIVAVAKGVQFSL"
     gene            39926..40153
                     /locus_tag="RH288_000895"
     CDS             39926..40153
                     /locus_tag="RH288_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDV4029984.1"
                     /translation="MRVDELVQFFGSVQRVADFYGITREAIYMWRKRPGEIVPKGRAA
                     EAAAYSKGKLSLNPELYKKKDNTLNEGKNDS"
     gene            40150..40575
                     /locus_tag="RH288_000896"
     CDS             40150..40575
                     /locus_tag="RH288_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HDV4029985.1"
                     /translation="MKIKHEHIRMAMNAWARPDGEKVPAAKITRAYFELGMTSPELYD
                     DSHPEALARNTQKIFRWVEKDTTDAVEKIQALLPAIEKAMPPLLVARMRSHSSVYFRE
                     LVETRERLVRDADDFVAVAIAGFNQMNRGGPAGNAVVMH"
     gene            40599..41561
                     /locus_tag="RH288_000897"
     CDS             40599..41561
                     /locus_tag="RH288_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310303.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV4029986.1"
                     /translation="MSSKLHGLVWEGCAFTGMILSRVAVMARLADYSNDEGVSWPAVE
                     TIRRQIGAKSESTVKAAIAELEKNGWLTKEERKVGGRNESNIYRLNVEKLEAAAEAAR
                     EAYKPKRKISPAKNDPLTVDQSNIAPSTIDPSNFDGSTVCKKQPVRGAMVGPDPSVLK
                     PDPSDKRSFRPEASQPDPQTAEQDFLTRHPDAIVFSAKKRQWGNQEDLACAQWIWGRI
                     VSLYEQAASDDGEITRPKEPNWTAWANDVRIMRMLDGRTHRQICEMFGRVQRDPFWVK
                     NIMSPSKLRDKWDELVIRLGRSPVQRCVNHISEPDTEIPPGFRG"
     gene            41606..42400
                     /locus_tag="RH288_000898"
     CDS             41606..42400
                     /locus_tag="RH288_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HDV4029987.1"
                     /translation="METLIDTLKAMQKVTCTELAASLGIEPAEAIKMLREYEELGEVV
                     SVNGYWSVSERQTGVKEKKVTVCKVERKSHPVVSRKEREPLKRCEILSTLAHSGAMTT
                     AEIAIAVGRADCVRSLVSAMEKLCRDGMAIKLGQGKGCKWMLVKETGENLPAEPKVVS
                     VAKTPGKAFSQSAGVALPVQEAATQEEIKTDTVGDIVQSLPSFTETRANGLILPSLHM
                     ASRELRRAKSHVQKWERVCAALRELNKHRDIVRQIVDSSSRIVSEK"
     gene            42417..42839
                     /locus_tag="RH288_000899"
     CDS             42417..42839
                     /locus_tag="RH288_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HDV4029988.1"
                     /translation="MAKVFTQEEREKIKGQIVDLVRQSGRETLRQLEAKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSAQARKDWQNARKKLSRANLKKTSVVDPDLIWSLPDG
                     EIRRYDRRQNIICSECRKSAAMQRVLAFYQGKFQEAIL"
     gene            42897..43253
                     /locus_tag="RH288_000900"
     CDS             42897..43253
                     /locus_tag="RH288_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029989.1"
                     /translation="MEIKPEDELSNIVLFPVKEDDPRNQVNFLYEPSERAYCHHASVR
                     VDEKERQVRCKICGAVVEPFDWMLSVAKRETRLADDVRLLRQEEQERRKNIEKLIQIE
                     RNAKARIRRATKSRTE"
     gene            43304..43516
                     /locus_tag="RH288_000901"
     CDS             43304..43516
                     /locus_tag="RH288_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029990.1"
                     /translation="MLNTQKTINAEKYNEWVRKFSEQIFKITGDENAAKNELEPWTPE
                     GLDQNYCWWDVDPVDAANETMSYHND"
     gene            43549..43767
                     /locus_tag="RH288_000902"
     CDS             43549..43767
                     /locus_tag="RH288_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4014 family protein"
                     /protein_id="HDV4029991.1"
                     /translation="MTTLFRKEYPRKSRATEFLFLILFIVLMIPISPLLLVWFIVKII
                     EPVIELYNDVVWASFNALHNKINPYKES"
     gene            43769..44134
                     /locus_tag="RH288_000903"
     CDS             43769..44134
                     /locus_tag="RH288_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDV4029992.1"
                     /translation="MALTKKQRAELRMKFGGRCAYCGCELGEKWHADHVKPVIRFDGN
                     MLHQERDDISNMVPACHPCNLHKHCSSLEDYRRIISDGRREFLASGKGKALVRMGLVE
                     MKSDPVVFWFEKYQEGATA"
     gene            44242..44475
                     /locus_tag="RH288_000904"
     CDS             44242..44475
                     /locus_tag="RH288_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001380403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029993.1"
                     /translation="MDIAVLEIALVSLAAEPAGKLHEYKPVGYQRLVDELTMLVKQLT
                     WQLRKAKPDCKLPDKAMSYLERNGLISVEDILR"
     gene            complement(44680..44979)
                     /locus_tag="RH288_000905"
     CDS             complement(44680..44979)
                     /locus_tag="RH288_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDV4029994.1"
                     /translation="MTYEVIITPEAEQQIINLHRYITEKAGNVIADNYANALLDYLDG
                     FSTFPHRGNKRDDIRQGMRVTHFRHRTIIAFAVDSRKVFIVGIYHGGQSYETDFL"
     gene            complement(44985..45242)
                     /locus_tag="RH288_000906"
     CDS             complement(44985..45242)
                     /locus_tag="RH288_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /protein_id="HDV4029995.1"
                     /translation="MRTTQQFSITLTNEMADMVRARVASGAYASESEVIREGLRALNE
                     RDKAIEAWLTHSAAPSLDSIRETPNNGRSISQVRAAIRSGK"
     gene            45378..45656
                     /locus_tag="RH288_000907"
     CDS             45378..45656
                     /locus_tag="RH288_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4029996.1"
                     /translation="MAHDTKLHNSDDSAVFASRCGRRFHAFKSDWFQHPPCTEEQAEW
                     IIQCYRRRGYEVKKALSLDYRHWIISVRLPYSERPPRPSRTFQQRIWR"
     gene            45658..46707
                     /locus_tag="RH288_000908"
     CDS             45658..46707
                     /locus_tag="RH288_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HDV4029997.1"
                     /translation="MRVLLRPVLVPELGLVIVKPGRESMPVFHNTRVLVEPEPKSMRN
                     LPSGVVPAVRQPLAEDKSLLPFFSDERVIRAAGGAGALSDWLLRHVKSCQWPHGDYHH
                     SETVIHRYGTGAMVLCWHCDNQLRDQTSESLEQLAHQNLSAWMIDVIRHAMNGTQERE
                     LSLAELSWWAVRNQVADALPEAVLRRSLGLRAEKIRSMYRESDIVPGEQTATSILKQR
                     TKNLAPLPHAHQQQNPPQEKTVVSIAVDPESPESFMKRPKRRRWVNEKYTRWVKTQPC
                     ACCGKPADDPHHLIGHGQGGMGTKSHDIFTLPLCREHHNELHADPLAFEEKHGSQVDL
                     IFRFLDHAFATGVLG"
     gene            46720..47079
                     /locus_tag="RH288_000909"
     CDS             46720..47079
                     /locus_tag="RH288_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDV4029998.1"
                     /translation="MLIDLVLPYPPTVNTYWRRRGSTYFISEEGKRYRRAVVLIVRQQ
                     RLKLSLSGRLAIKITAEPPDKRRRDLDNILKAPLDALMHAGLLIDDEQFDEINIVRGQ
                     LVPGGRLGIKITELECA"
     gene            47076..47741
                     /locus_tag="RH288_000910"
     CDS             47076..47741
                     /locus_tag="RH288_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator"
                     /protein_id="HDV4029999.1"
                     /translation="MNNQYLQFVREQLIIATADLSGATKGQLEAWQENAMFDTGRYRR
                     KKIRYRDEVTGKMITRDNPPIPGKQSLAKGTSIPLVSPVEFSTSSWRRAVLSLEEHHK
                     AWLLWCYSGSICWEHQIAITQWAWTEFNAQSGTRKIAGKTLVRLKTLIWLAAQAVKAE
                     LFGGEGYEYQELALLVGVTTKNWSKTFTGHWVAMKHIFHRLDGEALLLVEGTRSKQKA
                     AFS"
     gene            47996..48709
                     /locus_tag="RH288_000911"
     CDS             47996..48709
                     /locus_tag="RH288_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030000.1"
                     /translation="MDDSALLRNSSLFVAYMGCLGWGSAYFYGWGTSFYYGFPWWVVG
                     AGVDDVARSLFYAVTVIVIFLIGWGVGIVFFLGIKQKRNIQNLSFIRLFLAILLLFIP
                     PVLEFSVIHQHVEPDVLIFCILAAFTITLFVRFGRRLVSVKCFSEMSFIRHHRIEFMM
                     AGFMIYFWAFSLIAGWYKPQFKREYQAIHYENVWYYIIARYDDRLVLSKSYRSGGKKF
                     VIFNSGNINDFEINTVRVR"
     gene            48883..49080
                     /locus_tag="RH288_000912"
     CDS             48883..49080
                     /locus_tag="RH288_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDV4030001.1"
                     /translation="MLKQQDMTETARVVFNELSVTEPATVGEIAQNTYLSRERCQLIL
                     TQLVMAGLADYQFGCYRRLPQ"
     gene            49231..50316
                     /locus_tag="RH288_000913"
     CDS             49231..50316
                     /locus_tag="RH288_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HDV4030002.1"
                     /translation="MVDTVKISSCELINADCLEFIQTLPENSVDLIVTDPPYFKVKPE
                     GWDNQWKGDDDYLKWLDQCLAQFWRVLKPAGSLYLFCGHRLASDTEIMMRERFNVLNH
                     IIWAKPSGRWNGCNKESLRAYFPATERILFAEHYQGPYQPKNDGYAAKERELKQHVMA
                     PLISYFRDARESLGITSKQIAEATGKKNMVSHWFGTCQWQLPNEADYRKLQALFACVA
                     EEKHQRGELATPHQQLVSTYSELNRQYASLLEEYKSLRRYFSVSAAVPYTDVWTHKPV
                     QYYPGKHPCEKPADMLRQIISASSRPGDVVADFFMGSGATIKAAMGLGRRTIGVELES
                     GRFEQTVGEILVLNDKLRNAQLDKNRS"
     gene            50835..51113
                     /locus_tag="RH288_000914"
     CDS             50835..51113
                     /locus_tag="RH288_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030003.1"
                     /translation="MNIDDISRCSSLLQRIEDVNAERARAFSRLTVIFSTLDRLSGKN
                     IVLLNSDAIHKVFEEFMAANSELLALVEEYNEIASRVGMDEFNVILRG"
     gene            complement(51472..51741)
                     /locus_tag="RH288_000915"
     CDS             complement(51472..51741)
                     /locus_tag="RH288_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HDV4030004.1"
                     /translation="MQFLHKRMHLNAGDTVVVDCSHQCNILLMTDTNFNNYRNARSFH
                     HHGGGGFFQRLPAHLHVPHSGYWNITIDLGGGSAAIRHSISVIPA"
     gene            51941..52330
                     /locus_tag="RH288_000916"
     CDS             51941..52330
                     /locus_tag="RH288_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001406273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HDV4030005.1"
                     /translation="MSEPLSGSSTAVALGGATVFGLFTGTDFGIVFGAFAGALFVATM
                     PQVISVWRVAAHFLVSFIVGVLGADVLASWLVEKLNLHSTSLDALCAVLVSVVSVKIL
                     SFIHQQDIASLVSGLFSRLRGGGGNVK"
     gene            52320..52598
                     /locus_tag="RH288_000917"
     CDS             52320..52598
                     /locus_tag="RH288_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001753341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDV4030006.1"
                     /translation="MLSNLPGLLNVVLSTVIVLTLFFYRRGESRHKPLMSWLAWLLML
                     LYAFAPLCYLCGRFPPGNWLVVLINLVFCVLVIRARGNVSKILVLRRR"
     gene            52600..53145
                     /locus_tag="RH288_000918"
     CDS             52600..53145
                     /locus_tag="RH288_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 108 protein"
                     /protein_id="HDV4030007.1"
                     /translation="MKSKDEIFDEILGKEGGYVNHPDDKGGPTKWGITEKVARAHGYQ
                     GDMRDLTRGQALEILEADYWYGPRFDQVEDLSPDIAAELCDTGVNMGPTVASRMLQRW
                     LNVFNLRGKLYPDMDADGRIGPRTLNALRAYLKNRSRDGELVLVKALNCTQGERYLEL
                     AEKREANESFVYGWMKERVVV"
     gene            53306..53488
                     /locus_tag="RH288_000919"
     CDS             53306..53488
                     /locus_tag="RH288_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310767.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030008.1"
                     /translation="MRKYKLILLRLTMKNGLELKAPVTDDISRAVAFAIKWVAVGIAV
                     SPMLYGMAKLLIAVKS"
     gene            53645..53827
                     /locus_tag="RH288_000920"
     CDS             53645..53827
                     /locus_tag="RH288_000920"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030009.1"
                     /translation="MKRKHWTHRMPRTAAKWALVAILVPFFLVGCVSLDKARQLFDTA
                     SQVCGIVDGVRQCMQN"
     gene            53915..54124
                     /locus_tag="RH288_000921"
     CDS             53915..54124
                     /locus_tag="RH288_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030010.1"
                     /translation="MLTVKVMSQNGGEEIHCGRSIGYHPEQRSIAVSGKDGKVILKDG
                     DIAYVMNQNAQIISVYRPNNSQKNI"
     gene            55127..55633
                     /locus_tag="RH288_000922"
     CDS             55127..55633
                     /locus_tag="RH288_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDV4030011.1"
                     /translation="MAFLLNKSDMASSIGISVQAFDKWGVPPVERRGREVFYDVKTVL
                     EIDRERRQQNQKSSGGENDLEERLLQARVNLTEEQAIAQRLKNQVAEHKVIDTAFSIF
                     ALSRLSGELASVLDSIPLSMQRKFPELTGRQLAYLKELVAKGANKCVESAEKMKEFAD
                     EYYRNTDE"
     gene            55605..57530
                     /locus_tag="RH288_000923"
     CDS             55605..57530
                     /locus_tag="RH288_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HDV4030012.1"
                     /translation="MSITEIQMNNFVLAVKAGLSVLKRPLPMTPVEWADANYYLPKES
                     AYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTL
                     IWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFTNGRGFWCLG
                     GKAAKNYREKSVDVAGYDELAAFDDDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVR
                     GTCQIERAASESPHFMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEH
                     NACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFT
                     TWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDR
                     VAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYT
                     RRNGAEMSVSRICWDTGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNK
                     NGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQV
                     EKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAAT
                     NKKTLADYARALSGEDE"
     gene            57527..57733
                     /locus_tag="RH288_000924"
     CDS             57527..57733
                     /locus_tag="RH288_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gpW family protein"
                     /protein_id="HDV4030013.1"
                     /translation="MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTATSVSDLK
                     KYIAELEVQTGMTQRRRGPAGFYV"
     gene            57730..59331
                     /locus_tag="RH288_000925"
     CDS             57730..59331
                     /locus_tag="RH288_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV4030014.1"
                     /translation="MKTPTIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRAWNPPGES
                     VDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDHIVGSFFRLSHRPSWRYLGIGEE
                     EARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTS
                     PSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQK
                     WTWIPRELPGGRASFIHVFEPVEDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKA
                     MYAATIESELDTQSAMDFILGANSQEQRERLTGWIGEIAAYYAAAPVRLGGAKVPHLM
                     PGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANES
                     WAYFMGRRKFVASRQASQMFLCWLEEAIVRRVVTLPSKARFSFQEARSAWGNCDWIGS
                     GRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQEIFAQQVRETMERRAAGLKPP
                     AWAAAAFESGLRQSTEEEKSDSRAA"
     gene            59312..60631
                     /locus_tag="RH288_000926"
     CDS             59312..60631
                     /locus_tag="RH288_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HDV4030015.1"
                     /translation="MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLT
                     DAVSGDSLTAGEAPATLALSVNDDGPRQARSYQVMNGIAVLPVSGTLVSRTRALQPYS
                     GMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
                     NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHK
                     VDGNPYSHLPDDVRETLQSRMDATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAID
                     AGLADELVNSTDAITVMRDALDTRKSRLSGGRMTKETQSTTVSATASQADVTDVVQAT
                     EGKNASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVETAR
                     RILAAAPQSAQARSDTALDRLMQGAPAPLAAGNPASDAVNDLLNTPV"
     gene            60641..60973
                     /locus_tag="RH288_000927"
     CDS             60641..60973
                     /locus_tag="RH288_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HDV4030016.1"
                     /translation="MTSKETFTHYQPLGNSDPAHTATAPGGLSAKAPAMTPLMLDTAT
                     RKLVVWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAF
                     AGTAISIV"
     gene            61029..62054
                     /locus_tag="RH288_000928"
     CDS             61029..62054
                     /locus_tag="RH288_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HDV4030017.1"
                     /translation="MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQI
                     PGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLA
                     DPAYRRRRIILQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSEAN
                     NITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVKEKL
                     DTRRGSHSELETAVKDLGEAVSYKGMYGDTAIVVYSGQYVENDVKKNFLPDNTMVLGN
                     TQARGLRTYGCIQDADAQREGINASARYPKNWVTTGDPAREFTMIQSAPLMLLADPDA
                     FVSVQLA"
     gene            62096..62491
                     /locus_tag="RH288_000929"
     CDS             62096..62491
                     /locus_tag="RH288_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HDV4030018.1"
                     /translation="MTKDELIARLQVLGEQLNRDVSLMGTKEELVLRVAELEEELDDT
                     DDAAGQDTSVSPENALTGHENEVVSAQPDTVIDTAALVTVVALVTLHTDALHATRDEP
                     VAFVLPGTAFRVSAGVAAEMTEHGLARMQ"
     gene            62503..62856
                     /locus_tag="RH288_000930"
     CDS             62503..62856
                     /locus_tag="RH288_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HDV4030019.1"
                     /translation="MADSDNLFDAAIARADETIRGYMGTSATMTSGELSGAVIRGVFD
                     DPENISYAGQGVRVEGSSPSLFVRTDDVRQLRRGDTLTIGEENFWVDRISPDDGGSCH
                     LWLGRGVPPAVNRRR"
     gene            62868..>63340
                     /locus_tag="RH288_000931"
     CDS             62868..>63340
                     /locus_tag="RH288_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4030020.1"
                     /translation="MAIKGLEQAVENLSRISKTAVPGAAAMAINRVASSAISQSASQV
                     ARETKVRRKLVKERARLKRATVKNPQARIRVNRGDLPVIKLGNARVVLSRRRRRKKGQ
                     RSSLKGGGSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPL"
BASE COUNT        16082 a        14757 c        16818 g        15683 t
ORIGIN      
        1 ttcatatttt ttaagagtga ctatttatga aaacttgcat aacaaaggga attgtgaccg
       61 taagtttaac ggcaatatta ctcagctgct catccgcatg ggcggcaggt aaaggcggga
      121 ttggacttgc agcaacacgt cttgtttatt cagaaggtga agagcaaatt tcactgggtg
      181 tacgtaacac cagtccggat gttccttatc ttattcagtc atgggtgatg accccagata
      241 ataaaaaatc agcagacttt attattacac caccgctatt tgtgctgaat ccggcaaatg
      301 agaatctgtt acgcattatg tacattggag cgccgttggc gaaagacaga gaaacccttt
      361 tcttcactag cgtacgggca gtcccttcaa caacgaagcg gaaagaggga aataccctga
      421 agattgccac acaaagcgtc atcaaacttt tctggcgacc aaaaggttta gcgtatccct
      481 taggcgaggc tccggcgaaa ctgcgttgca cttcgtcagc tgacatggtt acggtcagta
      541 acccaacacc ttatttcatt accctgacag acctgaaaat aggtggaaaa gtagttaaaa
      601 atcaaatgat ttcccccttt gataaatacc aattttctct gccaaagggg gccaaaaata
      661 gcagcgtaac gtatcgaacc atcaatgact acggggcgga aacgccgcaa ctcaactgta
      721 aatcgtaagc cgtcttcagt taagagagcg agatgtatag aactcatcga caacacagcc
      781 tgttaagctc tggtggagtg ccatcgttta ttggtgggct ggtggtgttt gtgtcggcag
      841 cgttcaatgc acaagctgaa acctggttcg atcctgcttt tttcaaagat gatccctcaa
      901 tggtggccga tttgtctcgt ttcgaaaaag gacaaaaaat aacgccaggg gtttatcgtg
      961 tcgatattgt tctgaatcag acaattgtag atacgcgcaa cgtcaatttt gttgagataa
     1021 cgccagagaa ggggattgcc gcctgtttga cgactgaaag cctggatgca atgggtgtta
     1081 atactgatgc gtttccggct tttaaacaac tggacaaaca agcgtgtgtg ccattggcgg
     1141 agattattcc ggatgccagc gtaacgttta atgtgaataa actccgtctg gaaatttcag
     1201 taccgcaaat cgccatcaaa agtaatgccc gtggttatgt cccccctgaa cgttgggatg
     1261 aagggatcaa cgcgctatta ctgggatatt cgtttagcgg ggctaacagt attcatagca
     1321 gcgcagacag tgattctagc gacagctatt ttctgaattt aaacagtggc gttaatttag
     1381 gcccatggag attgcgcaac aattcaacat ggagtcgtag tagtggccaa accgcagaat
     1441 ggaagaatct cagcagctat ttgcaacggg cggttattcc tctgaaaggc gaactgaccg
     1501 taggtgatga ttatactgca ggcgattttt tcgatagtgt cagctttcgt ggtgtgcagc
     1561 tggcgtcaga tgacaacatg ctgccagaca gcctgaaagg gtttgcgcct gtggtgcgtg
     1621 gtatcgccaa aagcaatgcc cagataacga ttaagcaaaa tggttacacc atttaccaaa
     1681 cttatgtatc gcctggtgct tttgaaatta gtgatctcta ttccacgtcg tcgagcggtg
     1741 atttgttagt tgaaatcaaa gaagcggacg gcagcgtcaa tagctacagc gtaccgttct
     1801 ccagtgtgcc attactccag cgtcaggggc gaatcaaata cgcggtgaca ctggcgaaat
     1861 acagaaccaa tagtaatgaa cagcaggaga gcaaatttgc ccaggccacg ttgcagtggg
     1921 gcggaccgtg gggaacgacc tggtatggtg gtggacaata tgctgaatat taccgtgccg
     1981 ccatgtttgg tctgggattt aacctcggcg atttcggagc aatttcgttc gatgcgaccc
     2041 aggcgaagag tacgctagca gatcaaagcg aacataaagg tcagtcatat cgttttctgt
     2101 atgccaaaac gctcaaccac ttgggcacta actttcaatt gatgggctat cgctattcga
     2161 cgtcgggttt ctacaccctt tccgacacca tgtataaaca tatggatggc tacgaattta
     2221 atgacggtga tgatgaagat acgccgatgt ggtcgcgtta ttacaatttg ttttacacca
     2281 aacgtggcaa actgcaggtc aatatctccc agcaattagg cgagtacggt tcgttttatt
     2341 taagtggtag ccagcaaact tactggcata cggatcaaca ggatcggcta ttacagtttg
     2401 gctacaacac gcaaattaaa gatctttcgc tggggatttc ctggaactac agtaagtccc
     2461 gtggtcaacc tgatgctgat caggtgtttg ctctaaattt ttccctgccg ctcaatctgt
     2521 tgctccccag aagtaatgat agctatacca ggaaaaaaaa ttacgcctgg atgacctcta
     2581 acaccagtat cgataacgaa gggcacacta cacaaaacct gggtttaacg gagacattac
     2641 tcgatgacgg taacctgagc tacagcgtgc aacagggata taacagcgag gggaaaacgg
     2701 ctaatggtag cgccagcatg gattacaaag gggcgtttgc ggatgcccga gtgggctaca
     2761 actacagcga taacggcagt caacaacaac tgaactacgc tctttcaggc agtttagttg
     2821 cccattcaca gggcattacc ctggggcaat cgctggggga aactaacgtt ctgattgcag
     2881 caccaggcgc agagaatact cgtgtggcga acagcaccgg gctgaaaact gactggcgcg
     2941 gatataccgt tgttccttat gccacttctt atcgggaaaa tcgaatcgca cttgatgcgg
     3001 cgtcgttaaa acgtaacgtg gatcttgaaa atgcagtagt caacgtggtt cccaccaaag
     3061 gggcgttggt tctggcggag ttcaatgccc atgcgggtgc aagggtatta atgaaaacat
     3121 caaagcaggg tataccgctg cgttttggcg cgatagcgac gctggacggc gtacaggcta
     3181 atagcggcat aattgatgat gatggctcgc tctatatggc gggtttaccg gcgaagggaa
     3241 caataagcgt gcgctggggc gaagctcccg atcaaatttg tcatatcaat tacgagctta
     3301 ccgaacaaca aattaactct gcgattacgc gaatggatgc catatgcaga taatctttgg
     3361 agaaaaatgc gtgtcattac tacgactatt ttttgccgcc gtcttaatgc tatggtgcgc
     3421 tcaaaccgct gcttatagcg ggcagtgtca tactactcag gggaatccgt atattggcgt
     3481 caattttggc gttaaaaccc tggaggaaga agcaaatacg gcaggggtag ttaaagacaa
     3541 attttatcag tggaacgaat cgaatgatta ttatgtttcc tgtgattgcg ataaagacaa
     3601 tgtcagaagt ggccgatggg cattcgccgc ggattcaccg ttagtctatt taggcgacaa
     3661 ctggtacaaa attaatgact atcttgccgc caaagtttta ttgcaggtta aaggcagttc
     3721 tcctactgcg gttcctttcg aaaacgtggg cacagggggg ggatacccga tggcatattt
     3781 gcgaccctgg cggtcaacgt ttaggtgggc agggggcaag cggtaatagc ggtagctttt
     3841 ccctgaaaat attgcagccg ttcgttggct cggtcgtcat tcctcctatg gcgctggcgc
     3901 gattatatga atgctacaac atacccgcag gtgattcctg cacgactaca ggtacaccgg
     3961 ttttagtgta ttacctgtct ggtacgatca attcacttgg ctcatgttcc gtcaatgccg
     4021 gagagacaat tgaagttgat ttaggtgatg tcttcgctgc caatttccgt gttgtagggc
     4081 ataaacctct tggggccaga acggcagaac ttgcaattcc agtcaggtgt aacacgggaa
     4141 acgcgggatt agttaatgtc aacctgagtc tgacggcaac cacagacccc agctatcccc
     4201 aggcgattaa gacgtcacgt cctggcgtgg gcgtggtggt gaccgatagc cagaacaaca
     4261 ttatttcccc tgctggtgga acattaccgc tctctattcc tgatgatgca gacagtatcg
     4321 cgcgaatgaa tgtctatcca gtcagcacga caggtgtacc accagaaacc gggcgatttg
     4381 aagccacggc aacggtgaga ataaattttg attaacgcgt gaacgtatga agaaaaaaac
     4441 gatatttcag tgcgttatct tgttctttag cattcttaac atccatgtcg ggatggctgg
     4501 gcctgaacaa gttagtatgc atatttatgg gaatgtggtc gatcagggct gtgatgtcgc
     4561 caccaaaagt gcattacaaa atattcatat tggtgatttt aatatcagtg attttcaggc
     4621 cgcgaatacc gtaagcactg ctgctgattt gaatatcgat atcaccggtt gtgccgctgg
     4681 tattactggc gcggacgtcc tttttagcgg cgaggctgac acccttgcgc cgacactgct
     4741 caaactaact gacacaggcg gaagcggtgg tatggcaacg gggattgccg tgcaaattct
     4801 tgatgcgcaa agtcagcaag aaatcccgct caatcaggtc cagcctctta cgcccttaaa
     4861 agccggggat aacacactca aatatcaact tcgttataag tccacaaagg cgggagcaac
     4921 gggcggtaat gcgacggcgg ttctctattt tgatctggtt taccagtgaa ggagtgatgt
     4981 tgaaacggat aatctggatt ctgttcttat tgggattaac gtggggctgt gagctatttg
     5041 cccatgatgg cacggtcaac attagcggat cgtttcgccg taatacatgc gtgctggcac
     5101 aggatagcaa gcaaatcaat gtgcagttag gcgatgtctc gctgacacgt ttttctcatg
     5161 ggaattatgg cccggagaaa tctttcatca ttaatttgca ggattgcgga acagatgtca
     5221 gcacggttga cgtcaccttt tcaggaaccc ccgacggagt gcagagcgaa atgttgtcca
     5281 ttgaaagtgg tacggatgca gccagcgggc tggcaattgc gattctggat gatgcgaaga
     5341 tattgattcc gcttaaccag gcgagtaaag actacagcct acatagcggt aaggtgccat
     5401 taacttttta tgcgcaattg cgacctgtca atagcgatgt gcagtcgggt aaagtgaatg
     5461 ccagcgcgac atttgtactt cattatgact aatacgtgga acagattggc gctcttgatt
     5521 ttcgccgttt tatcgctgct ggtggcgggt gaattgcagg caggagtggt ggtcggcgga
     5581 acgcgattta tctttccggc agacagagaa tcgatatcta ttttactgac taataccagt
     5641 caggaatcct ggcttattaa cagtaaaatc aaccgcccaa cgcgttgggc cgggggggaa
     5701 gcgtcgacag tgccagcacc attactggcc gctccgccac ttattctcct gaagcccggt
     5761 acgacaggca cgttgcgctt gctgagaacg gaaagcgaca tcttgcctgt ggatcgcgaa
     5821 acgctatttg agttaagcat tgccagcgtg ccatccggca aagttgaaaa tcagagcgta
     5881 aaagtggcga tgcgctcggt atttaaactg ttctggcgac ccgaaggttt gccgggcgac
     5941 ccgctggaag cttatcaaca attacgctgg acacggaatt cgcagggtgt acaactcact
     6001 aacccaacgc cttattacat taacctgatt caggtgagtg taaatggtaa agcgttaagt
     6061 aatgtgggag ttgtgccgcc taaaagccag cgtcagacaa gctggtgtca ggcaatcgca
     6121 ccgtgtcatg tcgcctggcg ggcgataaat gattacggcg ggttgagtgc aaagaaggag
     6181 caaaatctgc cctgaaacag gttcggaaaa cgtttgcgtt ttttttgccg caggtcaatt
     6241 cccttttggt ccgaactcgc acataatacg cccccggttt gcacaccggg aatccaggag
     6301 agttcatgta ctaccccttc gttcgtaaag cccttttcca gctcgatcca gagcgcgctc
     6361 atgagtttac ttttcagcaa ttacgccgta ttacaggaac gccgtttgaa gcactggtgc
     6421 ggcagaaagt gcctgcgaaa cctgttaact gcatgggcct gacgtttaaa aatccgcttg
     6481 gtctggcagc cggtcttgat aaagacgggg agtgcattga cgcgttaggc gcgatgggat
     6541 ttggatcgat cgagatcggt accgtcacgc cacgtccaca gccaggtaat gacaagccgc
     6601 gtctctttcg tctggtagat gccgaaggtt tgatcaaccg tatgggcttt aataatcttg
     6661 gcgttgataa cctcgtagag aacgtaaaaa aggcccatta tgacggcgtc ctgggtatta
     6721 acatcggcaa aaataaagat acgccagtgg agcagggcaa agatgactat ctgatttgta
     6781 tggaaaaaat ctatgcctat gcgggatata tcgccatcaa tatttcatcg ccgaataccc
     6841 caggattacg cacgctgcaa tatggtgaag cgctggatga tctcttaacc gcgattaaaa
     6901 ataagcaaaa tgatttgcaa gcgatgcacc ataaatatgt gccgatcgca gtgaagatcg
     6961 cgccggatct ttctgaagaa gaattgatcc aggttgccga tagtttagtt cgccataata
     7021 ttgatggcgt tattgcaacc aataccacac tcgatcgttc tcttgttcag ggaatgaaaa
     7081 attgcgatca aaccggtggc ttaagtggtc gtccgcttca gttaaaaagc accgaaatta
     7141 ttcgccgctt gtcactggaa ttaaacggtc gcttaccgat catcggtgtt ggcggcatcg
     7201 actcggttat cgctgcgcgt gaaaagattg ctgcgggtgc ctcactggtg caaatttatt
     7261 ctggttttat ttttaaaggt ccgccgctga ttaaagaaat cgttacccat atctaattat
     7321 ttcttcgaat tcctctttat aagataatca gggctttatt ttcagccctg gttgttttat
     7381 attcatcgct gttgcttatt tagacatttt gtacttttat tgttgaggtt attaagcgaa
     7441 gcgacaatgg attgtgttgc tgcggtttta tagggtaggg gagaggcaga tgcgaattaa
     7501 accagacgat aactggcgtt ggtattacga tgaagagcac gatcgaatga tgctcgattt
     7561 agccaatggt atgctatttc gctcacgttt tgcgcgcaag atgttgactc cagatgcctt
     7621 ttctcccgca ggcttttgcg ttgacgacgc cgcgctctat ttctcttttg aagaaaagtg
     7681 ccgcgatttt aatttatcta aagaacaaaa agccgaactg gtgctgaatg cactggtagc
     7741 aattcgctat ctcaaaccgc aaatgccgaa aagctggcat tttgtttccc atggtgaaat
     7801 gtgggtgccc atgccgggcg atgcggcctg cgtttggttg agcgatactc acgagcaggt
     7861 caatttgctg gtcgttgaat ctggcgaaaa tgccgcacta tgcctgctgg cacaaccctg
     7921 cgttgttatt gcgggtcgcg cgatgcagtt gggcgacgcc attaaaatca tgaacgacag
     7981 gctgaaaccg caggttaatg ttgacagctt cagcctcgaa caggcagtct aacgcgccaa
     8041 cttaagtgca gtcttcggta cacagctaca gcaaagaatg gtgccatcat cgcccattgc
     8101 tgattttttc agcggcgtga cttcgccttc taaaagctga acacggcaac ttccacaaat
     8161 gcccgcgcgg caagaataag ggatacgaat tccctgattt tctaattgct ccagcaacac
     8221 ctgttggtta tttccacgaa atgcctgtcc ctgccagtca atatctacat ttgcgtccgg
     8281 ttgttgcgtg atgttggcgg tatcatcagc ggcagctgcg ccgtaaattt ttgccggagc
     8341 cgttgccaga atttccacct catcgccaac gcgaatcacg ccgctattac gggcaattaa
     8401 attctgacca aaatcgacat cgccgttatc ctgggcagtg cggaaagatt gcaatgtttt
     8461 taatggttcg cctgccggat gtttttgccc tttttctggg ctgacggtgg tgaaaataca
     8521 gcggctacaa ggtttaacca catcaaacac cacatcacca atgcgaatca ctttccagcg
     8581 atcttcttcc caggctgacg cgccggaaac caccagattg gggcggaatt gctccatttt
     8641 tacactggcc ggacaacgtt gttggagatc acgtaacgag gcttcgttag caagaaggta
     8701 aggatagcca tcagcaaatg acagaggtac agtgttgtgg cgtttcacgc gccgggtcat
     8761 ttgtggcccc acccagcgta attgcacttc gcgggagaaa aatccactta gccatttgtt
     8821 gatcgcgtct ggcgcaattc gcgcggtaaa atgtgtgccc caaacttcgg ttggtgcgtc
     8881 ttgtgtggcg aaatcagcaa aacgaacata tgcgctactg ccatctggtg cggtgagatg
     8941 caagccatca tgcacaggtg aaggagtaaa ccgtaccatc tggggaaact ggcgagcggt
     9001 aataaacgta ccgtcaggtt ccgtgatcat aaagatgcga tcgaaggcca gaccactgac
     9061 atctgccaga gcatgtgtaa gaccaatgcc gcgcatcgat ttaacaggat gaataaaaag
     9121 ccggattaat gtcgccacgg tgcggtcctc aaatgaaaat aagccctcaa ctttatgaca
     9181 tgacgcgctt attagctata atgcgcaaca attttcttag cgcctgtccc attaggctat
     9241 tttatttgtc agtttggccc tgggttatgc tcgaaatcct cacgtacttg tgtacgctcc
     9301 ggtttctccg cgctgtccat gtccagactg actgcaacaa ttacgcctac tgcggtaggc
     9361 tcttagagta aaagtgacga tatgaattct ctgtttgcca gtacggcccg tgggctggaa
     9421 gagctgttaa aaactgaact ggaaaacctg ggggccgttg aatgccaggt ggttcagggt
     9481 ggggtccatt tcaagggcga cacacggctt gtttaccaga gcctgatgtg gagccgcctg
     9541 gcctcgcgta ttatgttgcc gctgggcgag tgtaaggttt acagcgattt agacctctat
     9601 ctcggtgttc aggcgatcaa ctggacagag atgtttaatc ctggcgcgac cttcgctgtc
     9661 cacttcagtg gtttgaatga caccatccgc aacagtcagt acggcgcgat gaaagtgaaa
     9721 gacgcgatcg tcgatgcttt cacgcggaaa aatctgccgc gtccaaatgt tgatcgcgat
     9781 gcgccggata tccgcgttaa cgtctggctg cataaagaaa ccgccagtat cgctcttgat
     9841 ctgagtggtg atggtttaca tctgcgtggc tatcgcgatc gtgctggtat tgcgccgatc
     9901 aaagaaaccc tggcagccgc tattgtgatg cgatccggct ggcagccagg aacaccgctg
     9961 ctcgatccga tgtgtggttc cggtacgttg ctgattgaag cagcgatgct ggcgaccgat
    10021 cgcgcaccag gcttgcaccg tgggcgttgg ggctttagcg gctgggcgca gcatgatgaa
    10081 gctatctggc aggaagtgaa agcggaagcg caaactcgcg cccgtaaagg cctggctgag
    10141 tatagctctc atttttacgg ttcggacagc gacgcacggg tgattcaacg tgcacgcact
    10201 aacgcccgtc ttgcggggat tggtgaactg atcacctttg aggtgaaaga tgtcgcgcaa
    10261 ctgaccaatc cgctgccgaa agggccgtac ggcacagtgt tgagcaaccc gccatacggg
    10321 gaacgtctgg acagcgaacc ggcgctgatt gcgctgcata gcctgctggg tcggatcatg
    10381 aaaaaccagt ttggtggctg gaatctctct ttgtttagtg cctcgccgga tctgctaagc
    10441 tgcttgcagc tgcgtgcaga caaacagtac aaggcgaaaa acggcccgct ggactgcgta
    10501 cagaaaaatt accacgttgc cgaaagcact ccagacagca aaccggcgat ggtagcggaa
    10561 gactacacca accgcctgcg taagaacctc aaaaaattcg agaagtgggc tcgccaggaa
    10621 gggattgaat gttaccgcct gtatgacgcc gatctgccag aatataacgt tgccgttgac
    10681 cgttatgccg actgggtggt ggtgcaggag tatgcgccgc caaaaactat tgatgctcac
    10741 aaagcgcgtc agcgtctgtt cgatattatc gctgcaacca tttcggtact ggggattgcg
    10801 ccaaacaaac tggtgctgaa aacccgtgaa cgccagaagg gcaaaaacca ataccagaaa
    10861 ctgggcgaga agggcgagtt tcttgaagtt accgaatata acgctcactt gtgggtgaac
    10921 ctgacggatt atctcgatac tggtctgttc ctcgatcacc gcatcgcccg tcgtatgctc
    10981 ggtcagatga gcaaaggcaa agatttcctc aacctgttct cttataccgg cagcgccacc
    11041 gtgcatgcgg gattaggtgg tgcacgcagc accaccaccg tggatatgtc gcgtacttat
    11101 ctggaatggg cagaacgcaa cctgcgtctg aatggcctga ccgggcgtgc gcatcgcctg
    11161 attcaggccg attgcctggc gtggctgcgt gaggcaaatg aacagttcga tctgatcttt
    11221 atcgatccgc caaccttctc taactcaaaa cgaatggaag atgcgtttga tgttcagcgc
    11281 gatcatctgg cgctgatgaa agatttgaaa cgtctgctgc gtgcaggtgg gacgatcatg
    11341 ttctcgaaca acaaacgtgg cttccgtatg gatctcgacg gcctggcaaa actgggactg
    11401 aaagcacaag aaattacgca aaaaacgctc tcccaggatt tcgcccgtaa ccgccagatc
    11461 cacaactgct ggctgattac cgcagcctga aaggaatagt aatgtcatta atcagtatgc
    11521 atggcgcatg gctgtcgttc agcgacgcgc cgcttctcga taacgcagaa ctgcatatcg
    11581 aagataacga acgtgtttgt ctggtgggcc gcaacggcgc aggcaaatcg acgttaatga
    11641 aaatcctcaa ccgtgaacaa gggctggatg acggtcgcat tatttacgag caagatttga
    11701 ttgtagcgcg tctgcaacag gatccgccgc gtaacgttga gggtagcgtt tatgatttcg
    11761 ttgccgaagg cattgaagaa caagcggaat atctgaaacg ctatcacgat atttcgcgcc
    11821 tggtgatgaa cgacccgagc gagaaaaatc tcaacgaact ggcgaaggtt caggaacagc
    11881 tggatcacca caacctgtgg cagctggaaa accgcatcaa cgaagtgctg gcgcaactgg
    11941 ggttagatcc taacgttgcg ctgtcgtcgc tttccggcgg ctggttgcgt aaagcggcat
    12001 taggacgcgc gctggtgagt aatccgcgcg tgctgttgct tgatgaaccg acaaaccacc
    12061 tggatattga aaccatcgac tggctggaag ggtttttgaa aactttcaac gggacgatta
    12121 ttttcatctc ccacgaccgt tcgtttatcc gcaatatggc gacgcgcatt gttgatctcg
    12181 atcgcggcaa gctggtgacc tatccaggga attacgacca gtacctgctg gaaaaagaag
    12241 aagccctgcg cgtggaagaa ttacaaaatg ccgagttcga tcgcaaactg gcgcaggaag
    12301 aggtgtggat ccgccagggg atcaaagcac gccgtacccg taatgaaggc cgcgtacgcg
    12361 ccctgaaagc gatgcgtcgc gaacgtggtg aacgtcgcga agtgatgggt accgcaaaga
    12421 tgcaggtgga agaggccagc cgctccggta aaatcgtttt cgaaatggaa gacgtttgct
    12481 accaggttaa cggtaagcaa ctggtgaaag atttttctgc ccaggttcta cgtggcgaca
    12541 aaattgccct gattggtccg aatgggtgcg gcaaaaccac gctgctaaaa ctgatgctcg
    12601 gtcagcttca agcggacagc gggcgtattc acgttggcac caaactggaa gtggcttatt
    12661 tcgatcagca ccgcgcggaa ctggatcccg ataaaacggt gatggataac cttgccgaag
    12721 gtaagcaaga ggtgatggtt aacggcaagc cacgccacgt attgggctat ttgcaggact
    12781 ttctgttcca tccgaaacgg gcgatgacgc cggtacgtgc gctttctggc ggtgagcgga
    12841 accgcttgct gctggcgcgt ttgttcctca aaccaagcaa cttattgatt cttgacgaac
    12901 cgaccaacga tcttgatgtc gaaacgctgg aactgctgga agaactgatc gacagctatc
    12961 agggcacggt attgctggtt agccacgatc gtcagtttgt cgataacacc gttacagaat
    13021 gttggatctt cgaaggcggc ggtaaaattg gtcgttatgt cggcggttat catgatgccc
    13081 gtggtcagca agagcagtat gtggcgctca aacagcctgc ggtgaaaaaa accgaagaag
    13141 ccgccgcggc aaaagcagaa actgtaaaac gcagcagtag caaactaagc tataaattgc
    13201 agcgcgaact ggagcagcta ccgcaattgc tcgaagatct ggaggcgaag ctggaagccc
    13261 tacagacgca agtggcggat gcttccttct tcagtcagcc gcatgagcag acgcaaaaag
    13321 tgcttgctga tatggctgct gcagagcagg agctggagca agcctttgaa cgctgggagt
    13381 atcttgaagc gttaaaaaat ggtggctgat cgcaaaatag tcgatttaaa cagagacagc
    13441 tgacaacggt aaaattgcct gatgaactgg gtttatcagg catgaaaacc aacactttgt
    13501 tagtcatctg taaaatagcg catcattaag gagtaccaat gtgcgaacat catcatgccg
    13561 cgaagcacat cctgtgctcg cagtgtgaca tgctggtggc gttaccgcgc cttgagcatg
    13621 gtcagaaagc ggcatgtccc cggtgtggca caacgttaac cgtggcgtgg gatgcccctc
    13681 ggcagcgtcc caccgcctat gcgttggctg cactgttcat gctgttgctg tccaacttgt
    13741 ttccttttgt gaatatgaac gttgcaggag ttaccagtga aattacatta ctggaaattc
    13801 ccggcgtgct tttttctgag gactacgcca gcctcggcac ctttttcctg ttgtttgtgc
    13861 aactggttcc cgcgttttgt ctgataacca ttctgttact ggtgaatcgc gcggaattac
    13921 cggtccgttt aaaagagcaa ctggcacggg tgctttttca actcaaaacc tggggaatgg
    13981 cggagatttt cctcgcgggt gtgctggtca gtttcgttaa actgatggct tacggcagca
    14041 ttggggtagg cagcagcttt ctcccctggt gtttattttg tgtcctgcaa ctgcgcgctt
    14101 ttcagtgcgt tgatcgtcgc tggttatggg acgacatcgc cccgatgcca gaactgcgcc
    14161 agccgctaaa accaggcgtc acggggatac gtcaggggct gcgttcgtgc tcctgttgta
    14221 cggcaatcct tcctgctgat gaacccgtgt gcccgcgttg tagtaccaaa gggtacgttc
    14281 ggcgtagaaa cagcctgcag tggacactcg cgctgcttgt aacgtccatc atgctgtatc
    14341 ttccggctaa tattttgccc atcatggtga cggatttatt aggctcgaag atgccgtcga
    14401 cgattctcgc tggggtcatt ctgttatgga gcgaaggctc ttatcccgtc gctgcggtga
    14461 tctttctggc cagtattatg gtgccaacgt taaagatgat cgccatcgcg tggctgtgtt
    14521 gggatgccaa agggcatggc aagcgcgaca gtgaaagaat gcatttgatt tatgaagttg
    14581 ttgagtttgt aggccgctgg tcgatgattg acgttttcgt tatcgcggtg ctctcggcgc
    14641 tggtgcgtat gggaggttta atgagtattt atccggcaat gggtgcatta atgtttgctt
    14701 tagtcgtcat aatgacaatg ttttctgcta tgacgtttga cccgcgtttg tcgtgggatc
    14761 gtcaacctga atcagagcat gaggagtcct gacagtatgg aatctaataa tggggaagcc
    14821 aaaatccaga aagtgaagaa ctggtctccc gtgtggatat ttcctatcgt cacggcgctc
    14881 attggggcct gggttctttt ttatcattac agccatcagg gaccggaagt gaccctgatc
    14941 accgcgaatg cggaaggaat tgaaggtggc aaaaccacca ttaaaagccg tagcgttgac
    15001 gtcggcgtgg ttgaaagcgc cacactggct gatgatttga cgcacgttga aatcaaagcg
    15061 cggctgaatt ccggtatgga aaaattgctg cataaagaca ccgtcttttg ggtggtgaaa
    15121 ccgcagattg gtcgcgaagg gattagcggc ctgggaacgc tgctgtctgg agtttatatc
    15181 gaactgcagc caggcgcgaa aggcagcaaa atggataaat acgatttgct ggactcgcca
    15241 ccgttggccc cgcctgatgc gaaaggtatc cgtgtgattc tcgatagcaa aaaagccggg
    15301 cagctctcgc caggagatcc ggtgctgttc cgtggctatc gggtaggttc ggttgaaacc
    15361 agcaccttcg atacacaaaa acgcaatatc agctatcaac tgttcatcaa tgcaccttat
    15421 gaccgactgg tgaccaacaa tgttcgcttc tggaaagata gtggcattgc ggttgatctg
    15481 acgtcagcag ggatgcgtgt ggagatgggc tcattgacaa cgctgctgag tggcggtgtc
    15541 agctttgatg tgccggaagg tctggattta gggctgccag tggcaccgaa aacagctttc
    15601 gttttgtatg atgatcagaa gagcattcag gattcgttgt acaccgatca cattgattat
    15661 ctgatgttct ttaaagattc ggtacgcggt ctgcaaccgg gagctccggt agagttccgg
    15721 ggtattcgcc tgggtaccgt aagcaaagtg ccattctttg cgccgaatat gcgtcagaca
    15781 tttaacgatg attaccgtat tccggtactg attcgtatcg agccagagcg gctgaaaatg
    15841 cagcttggcg aaaatgcgga tgttgttgag caccttggcg aattgttgaa acgtggttta
    15901 cgcggatcgc tgaaaaccgg aaacctggtc actggtgcac tgtatgttga tctcgatttc
    15961 tatccaaata cgcctgcaat aaccggtatt cgtgaattta atggttatca gattatcccg
    16021 accgttagcg gcggcctggc gcaaatccag caacgactga tggaagcgtt ggataagatc
    16081 aacaaactgc cattgaatcc gatgattgaa caggcaacca gtacgctttc tgaaagtcag
    16141 cgcacaatga aaaacctgca aacgacgctg gatagcatga acaagatcct cgctagccag
    16201 tcgatgcagc agttgccgac ggatatgcag tcaacgttgc gtgaattgaa tcgcagcatg
    16261 cagggcttcc agcctggctc cgcagcctac aacaagatgg tggcggatat gcagcgcctt
    16321 gatcaggtgt tgcgagaact gcaaccggtg ctgaaaacgc tcaatgagaa gagtaacgcg
    16381 ctggtatttg aagcgaagga caaaaaagat ccagagccga agagggcgaa acaatgaaaa
    16441 agtggctagt gacgattgca gcactgtggc tggccggatg cagctccggc gaaattaata
    16501 aaaactatta ccagttacct gtggtgcaga gcggtacaca aagtaccgcc agccagggca
    16561 atcgtctgtt atgggtagag caggtcactg ttcctgacta tctggcgggg aatggtgtgg
    16621 tttatcaaac cagtgatgtg aagtatgtga ttgccaacaa caacttgtgg gccagcccgt
    16681 tggatcaaca gttgcgcaac accctggttg ccaacctgag tacgcaactg cccggctggg
    16741 tggttgcctc ccagcctctg ggaagcgccc aggacacgct caatgttacc gtaacggagt
    16801 ttaacggtcg ctatgatggc aaggtcattg tcagtggtga gtggctgttg aaccaccagg
    16861 gacaactgat caaacgtccg ttccgtctgg aaggagtgca aactcaggat ggttacgatg
    16921 agatggttaa agtgctggcc ggtgtctgga gtcaggaagc cgcttctatt gcacaagaga
    16981 taaagcgtct accttaatta taaagatttg taaatataac cgtctccggt atgttgcctt
    17041 aggcggtttt tttgtctcta acgtgcggaa aaatttgttc ctcttcacat tttttgtaca
    17101 accgacatgc ccgtgtagct cacaaatatg acagtggcgt gaattttgcg cattgacggc
    17161 agttatgatt cgcggtattg cttaactgtg attgcacatt tagtaatcac tgttttcttt
    17221 tccaccagaa accagtatga gggaaacgag gcatgaagag acaaaaacga gatcgcctgg
    17281 aacgggcaca tcaacgtggt tatcaggccg gcatcgccgg acgctcaaaa gaaatgtgtc
    17341 cctatcagac gctgaatcaa aggtcacaat ggctgggagg ctggcgagaa gccatggcgg
    17401 acagggtagt aatggcctga ttctgtctct ttaaaaagaa acctccgcat tgcggaggtt
    17461 tcgccttttg atactctgtc tgattataat cagaaggcag acgtatcctg gaacagaccg
    17521 actttcaggt cgctggcggt atagatcaga cgaccatcaa ccagcacttc gccatccgcc
    17581 aggcccataa tcagacgacg gttaacaatg cgtttaaagt gaatacggta ggtcactttt
    17641 ttcgctgtcg gcagtacctg accagtgaat ttcacttcgc caacgcccag cgcgcggcct
    17701 ttaccttcgc cgcccagcca gccgaggtag aaccctacca gctgccacat tgcgtccagg
    17761 cccaggcatc ccggcataac cggatcgcca ataaagtggc atccgaagaa ccacagatcc
    17821 ggattgatat ccagttctgc ttcaacatac cctttgtcga agttaccacc cgtttcggtc
    17881 attttgacca cacggtccat catcagcatg ttcggtgctg gcaattgcgg gcctttagcg
    17941 ccaaacagtt caccgcgacc agaggcaaga aggtcttctt ttgtatagga ttcgcgttta
    18001 tctaccatgt tctctgtaag ccttatttta ttgaagcacg caggatagct aacacgtgta
    18061 cgctgaacaa gtccgatcag ttcggaataa accagttcag ccaacgtaat ggccatggaa
    18121 aacggtgacg tccttcctgt tgcgatgctt gcgcgatacg ttcctggatg gtttgcatca
    18181 gcgtcgtttg gccttcgcca tcccacacca gatttaataa taacggcagt gcgtcagtca
    18241 catcgtctac tgcccagatg gtgaatttgc cttcttctac cgctttcacc agttcactgt
    18301 gaagacttaa atggcgaacg ttagctgtgg ggataatgac accttgtttc ccggttaact
    18361 cacgttgctg gcaaatagca aagaagcctt cgattttctc atttaaacca ccgaccggct
    18421 gggcgcgacc gaactgatcg actgaacctg tgatagcgat actctgattc accggcacat
    18481 cggcgagggc gcttatcagg gcgcagagtt cagccatcga ggcactatct ccatcaactt
    18541 cactgtatga ctgctcaaat gtcagcgatg ctgagaaggg gatctgttgc tcaagctgta
    18601 gttccgacat caggaacgct tgcatgatca tcatcccttt cgcatggata ttgccgccaa
    18661 gctccgcttt gcgttcgatg tcggtgaatt caccatcgcc aatatgcaca acgcagctaa
    18721 tgcgagaagg ttcgccaaaa gcgcgtggat gacccggaaa ttcaatgacc gaaagggcgt
    18781 taatttgccc gatgcgttcg ccttcggttt caatcaggat ttgctcctga aggatctcat
    18841 cctgcatacg ttcagcgagg aaaccttcgc gccattcacg ctgctgcagc attaagttta
    18901 gctgctcgcc ggagaaggtg tcgccatcac acagggaggc gacctcttta cactggcgga
    18961 ggatccactg cgggctaagc ggaagtgttt cttgttcacc ggtgtagcgt gctgcttcgc
    19021 ggataagtat cggccaggca tccgctcccg gtgcaggtaa gtgattatgt ctggcggtaa
    19081 atgtcaccca gcgacaccac tgggttactg actccgcatc gacaatctgc agagtatctt
    19141 caaattcgct ataaatagcc tgctctgaaa gctctggctc catctcctgg aaatcagcca
    19201 atgattcgcg ttcgcctacc agaatgactt tcagcttcaa tggcatcgaa ggcacagaga
    19261 cggggagagg gcgcgactca tcaaacgcaa cccagtcaaa acgctcgcgg ttaacgatat
    19321 ttttcagccg catccacagc agaggttgcg ccagcagtgt acgcaaagag ataatgagaa
    19381 taccgccatt tgcctgatgc accagaccag gctgcagggt aatgtcgcca ttaaactggc
    19441 gcaggcagcc aaagagttgc tccgcttcta cccagtcggc agcgacaact tgcgttaaag
    19501 tcgcaaaatt atcatctgca ctcactgcgt gacgtaagcg gatggagtgg ccggaaacct
    19561 catagtgacc gcccaccagt tggcctgcat cgctttgtag cgtacgcgcg gcattggcaa
    19621 taagattcag atactcagac tcttccgggg ccttcgccag cataaaagag gaggatgctc
    19681 gcgtatgcag caactgctcc agcgcaaatt gcagccgcgg ttgagtatca ctgaataaag
    19741 gatcgttttc gtcaatcaaa tgtggctgag caaatatttc ctgatagcta tcggtatcag
    19801 gaaccaggtc acgccatgca agtttcgtaa tggtcaaagt tgatgttttt tagtctgttg
    19861 tcaaagccgc gattataccg taaccggcac tacagcacac gtagaaagca ccgacaatac
    19921 tcctggcatg ggcgttaaag ctcacaggat ggagattctt ttcttcactg gcctaaaaag
    19981 ctgatattct gtaaagagtt acacggtaac attgagatcg ctatgaaata tcaacaactt
    20041 gaaaatcttg aaagcggttg gaaatggaag tatctggtta agaagcatcg cgaaggggag
    20101 ttaatcaccc gttacataga agccagtgcc gcccaggaag ccgtcgatgt gttgctctcg
    20161 ctggaaaatg aacccgtgct ggtaaatggc tggattgaca agcatatgaa tccggaactg
    20221 gtcaatcgca tgaagcaaac cattcgggca agacgaaagc gccattttaa tgcggaacac
    20281 cagcatacgc gcaaaaaatc gatcgatctg gaatttattg tctggcaacg tctggctggt
    20341 cttgcgcagc gtcgcggtaa aacgctttct gaaacgattg ttcagctgat tgaagatgcg
    20401 gaaaacaaag agaaatacgc gaataaaatg tcttctctga agcaggatct gcaggcattg
    20461 ctgggtaagg aataactgac gaaagtcagt tcaatttact aaaggcaaaa aaaaccccgc
    20521 agcagcgggg tttttctacc agacgagaac ttaagcctgc ggctgagtta caacgtcttt
    20581 gataccttta acttcgatct ctacgcgacg atccggagcc aggcagtcga tcagtgcagc
    20641 acgctgtttc acgttgtcac aggtgttgcc agtaaccggg ttggattcgc ccataccacg
    20701 tgcggagatc ttgtctgccg ggataccttt ggagatcagg taatcaacaa cagactgagc
    20761 acggcgctcg gacagaccct ggttgtaagc gtcagaaccg atgcggtcgg tgtaacccag
    20821 aacaactacg gaaccgtctt tcggatccag gttgctcagc tggctgtaca gctgatccag
    20881 agcagcctga ccttccggtt tcagggttgc tttgttgaag ttgaacagaa cgtcagactt
    20941 cagagtgaag tgcttggtct gtacttccgg tgccggagct ggagccggag caactactgg
    21001 agctgcttcg ccctgaccga aacggtagga aacacccagg ctcagcatgc cgttgtccgg
    21061 acgagtgccg atggtgtgtg cgtcaccgat gttgttggtc cactggtatt ccagacgggt
    21121 agcgatttca ggagtgatcg cgtactcaac accgccagcg aagaccggag aaacgccggt
    21181 gtcgtggttt ttaccataaa cgttggattt agtgtctgca cgccatacca tgccacccag
    21241 acgagtgtag atgtccaggt cgtcagtgat tgggtaaccc agtttagcgg tcagttgaac
    21301 gccctgagct ttgtatgcac cgttttcaac gctgcctttg tacggcatac gacctaacca
    21361 gtcgtaaccc atttcaaagc caacatacgg gttaacctgg taaccaccaa aagcaccagc
    21421 gcccagttgg ttttcatggg tcgggccatt gttgttgatg aaaccagtgt catggtactg
    21481 ggaccagccc agtttagcac cagtgtacca ggtgttatct ttcggagcgg cctgcgctac
    21541 ggtagcgaaa ccagccagtg ccactgcaat cgcgatagct gtctttttca ttttttgcgc
    21601 ctcgttatca tccaaaatac gccatgaata tctccaacga gataacacgg ttaaatcctt
    21661 caccggggga tctgctcaat attaactcta ccgatatctt cggcttatgc cgagcacccc
    21721 tggcgatgta aagtctacaa cgtagttgaa aacttacaag tgtgaactcc gtcaggcata
    21781 tgaaaaaaaa gtcttgtata aggtatgttt aatctttttt gtcagcgaca atttacagaa
    21841 gagaatcgcg gaaaccgctt cagacaagcc tccgcaagga aaattagtca cgactgaaag
    21901 cattggctgg gcgacaaaaa aagttccagg attaatccta aatttactta atgatacaaa
    21961 ttagagtgaa tttttagccc ggaaagttgt ctcgtggcgt gagaggatgc gcttaccgga
    22021 cgcataataa accccatagc gttaccttca tttgccgcat caacaagttc agcatgctct
    22081 tcttcagtca aatcatctgc caaccaaccg atcaccacac tgtaattgcc cgtgcgtaaa
    22141 gcgcgaacca ttgactccac agtgtggcaa ggggagagct ggctaatctg cattactttc
    22201 gttaagggta gcccagatgc ctgaacccat tcccgactca gtttttgttg cggtgttaac
    22261 cagagttgcc agcgcgattg ctgaccgagt tgctgtaaca atggcaacag tagaagttgc
    22321 gtcatcatgg gctgatcttc gcgatagaca acttcactga taagcccggc tgtagtgttt
    22381 tccgtagaga cacgcgcaat tttacttgct gcggatgaga acgacgaaga acgatgtgca
    22441 tagcctgaag tgtacataat caatccagcc cctgtgagtt actgtatgga tgtacagtac
    22501 atccagtgac aacaaagatc aaccctattt tcggaaagag cctcgcaaat tttgtcgttg
    22561 gtgacgggaa aacataaatt aatcttgccc cttaagaata agttgcctat tttcgtagtt
    22621 aacggatccg ttaatgtgaa tcattctttt atgttatgat tttaaaagga attttatgaa
    22681 aagcctctcc tataagcgga tctataaatc acaagaatac ctggcaacgt tgggcacaat
    22741 tgaataccga tcattgtttg gcagttacag cctgaccgtt gacgacacgg tgtttgcgat
    22801 ggtttctgat ggtgagttgt atcttcgggc ttgtgagcaa agtgcacagt actgtgtaaa
    22861 acatccgcct gtctggctga catataaaaa gtgtggccga tccgttaccc tcaattacta
    22921 tcgggttgat gaaagtctat ggcgaaatca actgaagctg gtgcgtctgt cgaaatattc
    22981 tctcgatgca gcgctgaaag agaaaagcac gcgcaatacc cgggaaagac tgaaagattt
    23041 gcccaatatg tcttttcatc tggaagcgat tctcggggag gtggggatta aggatgtacg
    23101 ggcgttacgt atacttgggg caaaaatgtg ttggttgcga ctgcggcagc aaaacagtct
    23161 ggtgacagaa aagattctgt ttatgcttga aggtgccatt atcggcattc atgaagctgc
    23221 gctcccggtg gcacgccgcc aggagcttgc agaatgggct gactctctta cgccgaaaca
    23281 ggagtttcct gcggaacttg agtaatctgg cgttgcagac gaccaatctc aggcagtaat
    23341 gcaatcaata atccaacttg ttgtacgacc agaggttctt tgctgtctgc ccgtggttca
    23401 agttgctgca tccgctgttt caggctagct aatgcctcat tgacgcgttc ttcatcagca
    23461 ggttgatgat gtaacgcgtc atcaacatag caaactgcgt catcaagaaa cgccagaatt
    23521 tcaggattag ttaactgctc ccggtgagca ccgagggctg agatatagct ggtaaacgta
    23581 tggttaaggc acagcaaccg aaacgcggct tcgcgaattt gcggggtaac gttcggctcg
    23641 ctggacatat ttgataccac cgacgccagc tcagcatcac ggttgtgtgc atcgcggcgg
    23701 gcaatacgat acgccagacg gttatcacgc ccctgatggt attgctccag tatggcatcg
    23761 agataccgac agttggcctc tgtggcgcgt tcgagcatgc gcggcagatt gcgaaactgc
    23821 cagtcaggcc agatgtagct cactgccgcc cacgcaatgg cacaaccaat cagcgtatcg
    23881 attacgcgag gtaacgctac ttcaaaacct tcacccagta agttaaaaca cagtagcacc
    23941 aaaagtgtga tgaacatcgt tgcatgagcg tattgcacgt tacggaaggc aaaaaagagc
    24001 acgccggtaa taaccagcag caccagctgc ccttccagtg atggcacaaa ccacagcaca
    24061 ggaatgccaa tggcgatacc taccagcgta ccaataatcc ttaacttcag gcggtggcgc
    24121 gtggcgttat agtttggctg gcagacaaac aaacttgtca gcaagatcca atacccgtga
    24181 tgcattccgg ttatctgaat gatggcgtag ccgaagcaca acaccagcga cattcttacc
    24241 gcatgacgga agagggcgga ttccggcgtg aagtgacggc taagacgcag ccagatatca
    24301 ctcaacccgt gcgggctgtc atcagcgagc tcattttcgt cattattatg gggtagtgcc
    24361 tgggcctgtt ctgattcaat tgttgccagt tgggcatcaa tggcgcgtaa attgttcagc
    24421 aaaaatccca gtgttttgag taaatcggcg ggtgcgccgt tatcgcgcat ccgctccagc
    24481 gcagcatcaa tatgcgtaaa agcgcgctca aaatgcggat catgttgata aggctgacgc
    24541 aacaaaatac agcgtgacag ttgctggcac gcctggccct gcatcgacat cagccgctga
    24601 aaacggaaca gcacgtcgct gtggcgaaaa tgttcacgca atgtttgata ctgaatatga
    24661 gaagagctgg cacgctcgtg aatatcctgt gcgacaaagt aataatgcag cgtgcgacgc
    24721 gttccccgtt gaccacgatc gccacgtaag cgggtcagca gcgagagttt cgtctgattc
    24781 aatgtcgcca tcagcagacc gttggcgaga gccaaatcgt acagcggtgc ctggctttga
    24841 tcttcaatat caggatcaaa catgcgcgac ttgagctcaa gataacgcgc cagttgttca
    24901 tagcaacgcg ccaggttgtc ctgcagcggg cggaccggga acagcagatg accaataagt
    24961 gtcaggacgt tgtaccagac ggcaccggcc agcagataca tcggctgctg ataccagtgc
    25021 tcatacagtg atgttcccaa catagtgtaa atggcgatca gcaatgcacc gaaggcaatt
    25081 gttgcatagc gttgacccag accgccgagc aaaatgaagc cgctggtaga gagcgttaag
    25141 ccaatcgcaa atagccaggg ccagggaaac agcaattcta ctgaggccga ggcgataaaa
    25201 aagcagaaca gcgtaatgat gaggttacgc aaacgtcccg ccagtcggtc atcgagatcg
    25261 gtcagcgccg ctgccaccat ccccagcgtt agcggaatcg tcagttttac atcacccagc
    25321 caccacggaa acgctgtggt tccacaaagc gcaataaaaa tacgcgcgta atacagccag
    25381 gcgctgttcc aggtatagcg tttgagcaaa ggacttagca taaaggccat attagtggat
    25441 tattcaaaac gacgacgtgc attggcttca cgcgcagctt gcgctgtttc taccgatacc
    25501 acgcgacgac caaccggcca tagtgcaata gcggcaattt taaagttcgc aatgccgaca
    25561 ggaatgccaa tgattgaaat acattgtgcg atgcccgttg caatgtgcat caggcataac
    25621 caccagccaa agaaaatcag ccagaaaata ttcaataccg taccgccagt attcagcagc
    25681 acatttttgc cagccgggtt cagttcatcg acatgaatag cttcattgcc ataaggcacc
    25741 agagacagtt tagtgatctc ccagcaggat cgtgtcagcg gtaaggtaaa aatcagcaca
    25801 atactgacca gagtcgctaa cagccagccc agagtggtgg caaatccgcc aagcacaaag
    25861 ttcagaatgt tcaaaacggt acgcataaaa cctcgcttta ctgtggtttt cagtaatggg
    25921 cggcaattgt aacgtttttt tgggctggag cacgttttct ctgacggtta cactgataag
    25981 aaataatttc gtgtggatct acagagtcat ggaactgaaa gcgacaacgc ttggaaaacg
    26041 tctggcacag cacccttacg atcgggcggt gatcctcaat gccgggatta aagtctccgg
    26101 cgatcgccac gaatacctta ttcctttcaa tcaattactg gcgattcact gtaagcgcgg
    26161 tctggtatgg ggcgagctgg aatttgtact gccggacgaa aaagtggtgc gtctgcacgg
    26221 caccgaatgg ggcgagacgc agcgttttta ccatcatctt gatgctcact ggcggcggtg
    26281 gagtggcgag atgagcgaaa ttgcgtctgg tgttttacgc cagcaactgg atttgattgc
    26341 cacgcgcact ggggaaaata aatggctgac gcgtgagcaa acctctggcg tgcagcaaca
    26401 aatccgccag gctttgtcgg cgttgccgtt gccggttaac cgactggaag aattcgataa
    26461 ctgccgtgag gcgtggcgta aatgtcaggc ctggttgaaa gatattgaaa gcgctcggtt
    26521 gcagcataac caggcgtata ccgaagccat gcttaccgag tatgcggatt ttttccgcca
    26581 ggtcgagtct tcaccgctga atccggcgca ggcccgggca gtcgttaatg gcgagcattc
    26641 tctgttagtg ctggcaggtg caggaagcgg aaaaacgtcg gtgctggtgg cccgtgcagg
    26701 ctggttgctg gcgcgtggtg aagcgtcccc tgagcaaatt ttattgctgg cgtttggtcg
    26761 caaagccgct gaagagatgg acgagcggat tcgcgaacgg ctacataccg aagacattac
    26821 cgcacgcacg tttcatgcgc tggcgctgca tattattcag cagggcagca aaaaagttcc
    26881 gatagtcagc aaactggaaa atgataccgc tgcccgtcat gaactcttta ttgctgagtg
    26941 gcgcaagcaa tgcagcgaaa agaaagcgca ggcgaagggc tggcggcaat ggctgacgga
    27001 agaaatgcag tggtcagtgc cagaaggtaa cttctgggat gatgaaaaat tacagcgtcg
    27061 ccttgcctct cgcctcgatc gctgggtaag tctgatgcgg atgcacggtg gtgcacaggc
    27121 agaaatgatt gccagtgcac ccgaagagat tcgcgatctg ttcagtaaac gtatcaagtt
    27181 gatggccccg ttattaaaag cctggaaagg tgcgctgaag gcagaaaacg ctgtcgattt
    27241 ttcgggcctt attcatcagg cgattgtgat tctggagaaa ggtcgcttta tcagcccgtg
    27301 gaagcatatt ctggttgatg aatttcagga tatctcgccg cagcgggcag cgttgttagc
    27361 ggcattacgc aagcaaaaca gtcagacgac gttgttcgct gttggtgatg actggcaggc
    27421 gatttaccga ttcagcggtg cgcaaatgtc gctcaccacc gctttccatg aaaactttgg
    27481 tgaaggcgaa cgctgtgatt tagacacgac ttaccgtttt aacagtcgta tcggtgaggt
    27541 ggcaaaccgg tttattcagc agaacccagg ccagctgaaa aagccgctaa acagcttaac
    27601 caatggagac aaaaaagccg tcacgttatt ggatgagagt caacttgacg ctttgctgga
    27661 taagctctct ggttatgcca aaccggaaga gcgcattctg atcctggcgc gttaccatca
    27721 catgaggcct gccagcctgg aaaaagcggc aacacgctgg ccgaagttgc aaatcgactt
    27781 tatgaccatt catgccagca aagggcaaca ggcggattac gtcatcatcg ttggcttgca
    27841 ggagggaagt gatggttttc cggctgcggc gcgggagtcg attatggaag aggcgctact
    27901 gccaccggtt gaggatttcc cggacgctga agaacggcgg ttaatgtacg tggcgctgac
    27961 ccgggcacgc catcgggtat gggcactgtt taacaaagag aatccctctc cctttgtgga
    28021 aatactgaaa aatctggatg tgccggtggc gagaaaaccg taagaaacag gtggcgtttg
    28081 ccacctgtgc aatattactt cagacggtcc gcgagataac gctgataatc ggggatcaga
    28141 atatcgaccg cgtcgttgaa atgcggcgac tggattatga agtctgccgt tgccacgttg
    28201 gtggcgaccg gaatgttcca taccgtcgcc agacgcagca aggctttcac gtcaggatcg
    28261 tgcggcacgg catttagtgg atcccagaag aaaatcaata catcaatttt cccttctgag
    28321 atcaatgcgc caacctgctg gtcacccccc attgggccac tcaacatcgc gttgacgttc
    28381 atgccggtcg cgcgggaaat taagttaccg gtagtgcctg ttgcatacag tacgtgttgt
    28441 tccagtaacg gttgatgccg ttccacccag ctcatcagca tttgtttgca gtgatcgtgt
    28501 gccaccagcg caatatgttt ccgcgcaggt aaagtgcgag tcgtcagttc cataatgtac
    28561 atccgtagtt aactttccta cagattactg taagcactta tcgctgcaag ataaagaccg
    28621 aaaaagcctg cgcacaggca caaaaatctc aggaagatgg ttgtttttcc gcccactgca
    28681 ggaaagtatt tcgcgtttgt gggtcagcca gtttaaacca atacttcagc cgttgttctg
    28741 tgagcacctg agactgcggt ggaatagcat ccagctcgga aacacccgaa agcagcgtac
    28801 tgtcatctgc catcatcgtg gcaaattgcg gtagtgaagc gcgtttcgcg gatttgttat
    28861 agcgttcaac ctcgacctca taatcaatcg tttttgccgt tgaggtaatg gcgagaatat
    28921 ccagctttac cggaatcggc gtcgcatcgc catccaacaa ttcaaggcgc ggcgcggcat
    28981 caaaatggtt agcttcccgc tcattctcca ggcgaggcag gcgaaaattg acctggttga
    29041 tgagctgggt attaaaactg accaccagcg gtggggagat atacagccgt tcttcactat
    29101 tggaaagatg aatcgtcttc tcaacgcgaa acactaactg atgcggtcca ttatccagtt
    29161 caatgctgtc cgcaccgcgc agcagagagc tggaaacctt cttgccgtcg agtaccagaa
    29221 gatcgacatc ggttgaaagc cgcagcgtgg tggcaaaaac ggataccggc aaacataatg
    29281 caatcaaggt ggtcacgatg ccggttttca taggtagctc ctgtcaaaag accgcccgaa
    29341 taataatgtg tcaaaatttt tctttaatca tacttactaa catatagaca tatttcccgc
    29401 ttttgctctc attcattcgt attagctgca tggttggcat gtcggctttg tcgtacactt
    29461 tgttaaacag tctggaggaa ataatgaaag aaaccgatat tgcaggcatt ttaacgtcca
    29521 ctcacaccat tgcgctggtg ggggcaagcg acaaacccga tcgtcccagc tatcgcgtga
    29581 tgaaatatct actcgaccag gggtatcacg tcattccggt ttcgccaaaa gttgccggca
    29641 aaacgctgct gggccagaag gggtatggca cgctggcaga cgttccggaa aaagtcgata
    29701 tggtcgatgt tttccgtaat tcagaagcgg cgtggggcgt ggcacaggaa gctattgcca
    29761 ttggcgcgaa aaccctctgg atgcaactgg gggtgattaa tgagcaagcg gcagtactgg
    29821 cacgggatgc cgggttaaat gtggtgatgg atcgctgccc ggctattgag atccctcgcc
    29881 tgggcctggc caaataaaaa atccccggaa ggcaaaaacc ttccggggat ttgttcaggg
    29941 attagttacg cagacgcggg gcctggagtt gtttgcggat ggtctgcgcc agctcatcca
    30001 tggatggctg ttcaggatgt tcatcctgca attcgctact tagctgggct tcagccaggt
    30061 aggtatgaac cggtaggccg ttatcgtcct ccatcactac gtgataccac ggagcggcgc
    30121 gaagctcgtc attcaccgcc agctcatcag gcgacggttc agagagcgaa taaaccgggt
    30181 cgatatccac gaccactccg agataaccta acagggaatg gcggacctgc tggccgatac
    30241 cgaatttgct ggcaatcata gtcacctccc gggaaatctt tacctttgat ataagggtaa
    30301 aattccacat ttcaagttac atgacgcgac aggcaaaccc tttcagatat agcccttccg
    30361 gataggtagc gatcaccgga tgatcggctg cctgacggaa ctgctctata aattgtacat
    30421 cacgaccggc atcaattgcg gcatccgcga tgattttctg aaataaatcg ctggtcatca
    30481 gaccggaaca ggagaaagtc aggagaatac cgccttcatt cagcagctga atcgccagca
    30541 tgttgatgtc tttataacca cgacacgcgc ccatcaactg gcttttattc tcaacaaact
    30601 tcggcgggtc catcacgata acgtcaaatt tttcaccgcg atcgcgataa gtacgcagca
    30661 atttaaagac atcatcacgg acaaactcag ccttgctcag atccagtttg ttcagctcaa
    30721 cgttctgccg tgcaatatcc agcgcttcct gggaggtatc aacgctgaca acctggctgc
    30781 aaccgcccat cagtgccgat acggcgaaac caccggtata ggagaaacag ttcagcacac
    30841 gtttattttc aacgtagcgg cgggtagcca ggcggctatc acgctggtcc aggtagtagc
    30901 ccgttttgtg tccgtgctga atatccacca gcagtttcat tccgtgttct tcaatcggca
    30961 gcagggcagg tggcaactcg ccggtgacgg ggccctgggt cagctccatt ccttcttttt
    31021 tacgtaccgc gacgtcgctg cgatcgtaaa tcgaacattc cgggtacagc gtttgcaggg
    31081 cactaattaa tgccgcgcgc tgatattctg ccccagcact cagcagttgc agcaccagaa
    31141 aattaccgaa acgatcgata gtaatacccg gcaggccatc agattctccg gcgattaaac
    31201 gatagctgtc gaggccatct ttttgcgcca gccagtcacg ccatttttgt gcttgttgca
    31261 aacggcggga aaaaaaagca atgtcgatag actcagacgg gtcaaacgtc cagacgcgcg
    31321 cccggatttg cgaagctggc gaataagcgc cgcgtgctaa ccattttccc tgatgatcaa
    31381 caatatcgat ggtttcaccg aggctggctt taccttccat gcgggcaacg gccccggaaa
    31441 agacccacgg atggcgacga agtaatgatt tttcgcgccc tttggctaac actaaacgta
    31501 cactcataat ttacttttct gtcgatgcaa agaaatgggc gtcattgtcc ggagttttcc
    31561 atggatttgc aacgcgtcca ttaaggataa ggagagcagc aatgtcgaaa gtctgcataa
    31621 ttgcctgggt ttacgggcga gttcagggcg taggatttcg ctacaccaca cagtacgaag
    31681 cgaaaagact gggtttaacc gggtacgcca aaaatcttga cgatggcagc gtggaagtgg
    31741 ttgcttgcgg tgaagaaggg caggtggaaa aattaatgca gtggttaaag agtggcggcc
    31801 cgcgttctgc gcgtgtagaa cgggtgctca gcgagccgca tcatccctcg ggggaattaa
    31861 ccgattttcg tatccgttaa atacatttta ccggttttgg caggccagca attttggtgg
    31921 cttgcttagc cggacctttc ggaaacagtc ggtataaata gcggctgtta cctttttctt
    31981 cgccaaattt attcgccatc gcttttacca gcatacgaat cgccggagaa gtattgaatt
    32041 ccagatagaa atcacgcaca aaacgcacca cttcccagtg ttccggtgac agcgaaatcc
    32101 cttcgttctc tgcaatcacc acagccagcg gctcactcca ctggctgctt tctttgagat
    32161 agccttcggt atccgtttct atctctttac cttcgaagat cagcataatt attactacct
    32221 taatcagact ggcggcagtg taacaaaaaa caaagccccg cataaagcga ggctatgaaa
    32281 gtgttagcgg gtgagattaa tcgcggctag cgaagcccag aatgctcagc aggctgacga
    32341 agatgttgta cagcgaaaca tacaggctaa ccgtggcacg aatatagttc gtctcaccgc
    32401 catgaatgat gttgctggtt tcaaacaaga tagcgccaga ggagatcaga atgaagaccg
    32461 cgctgatcgc cagatgcaga gcaggcagct gcaggaagat attcgcaacc ataccaatca
    32521 gcaccaccac aatacccgcc atcagcatac cgccgaggaa cgacatatct ttgcgggtgg
    32581 tcagcacata tgcagagcag cagaagaaca ctaacgccgt tccgcccagt gccatagcga
    32641 ttacgtcacc cattccggca gacagatagg tgttcagaat aggtccgagg atataaccca
    32701 gaaaaccggt aaaggcgaat gcggagataa tcccggtcgg cttattcgcc gttttatagg
    32761 tcaggaacat caaaccatac atacccacca gcgtcagaat cagacccgga gatggcagca
    32821 tcagcaccgt actggcagtt gcggtaatcg ccgaaaaggc cagcgtcagg ctcagcagaa
    32881 aataggtatt acgcagcacc ttatgggtgc taagcagtga tgtacggtca tgtgaagaac
    32941 taacaatacg atccattgag tcactctcta tgacagatgt aattaattaa gcagcataat
    33001 gataatgcgt aagggcaccc agaagtttta cccatcttta cgcatttgat ctggaacagg
    33061 tttaacagcg gattatcagg tcattaagca aatataacgc cctgagaatt tcgacaggca
    33121 aaagaaaaag gggttagcat ttagctaacc ccttatctta tttggcggaa gcgcagagat
    33181 tcgaactctg gaaccctttc gggtcgccgg ttttcaagac agaagaaaaa taaagaaaaa
    33241 tcagtataat acggaaaatg gccgaaaagt taatcagact tgacaccaag aaaaatcaat
    33301 atattaggga gttattcaga gttaatatac caagtctttt tgccagaaaa ttttctgtat
    33361 tgcctactta ctgaccacaa gcggcaaatc cagtgttggt gttattttgg ttttacgatc
    33421 gtaaatcaac acctgatttt ctgttttgtg tccactgaaa atttgtttgt cgcgactgct
    33481 gccttcgtaa tctgaaatcc ctttggcttt tatgtcatgg aagttgcacc caaacggaac
    33541 gccggctttt tgctcggctg cacgtttagc ctgattccac cagttgttca gcgtcttggc
    33601 tattaccttc ccgcctttgg ttgtgttgat cacatactcg catgtgccgg aagatacatt
    33661 tcgggctaac tggatcgccg tacgtaatcg cggagaccat tccttgattt gtttagtgcc
    33721 ggtcttgttt tgctcaatgt aaatcccttt ctccataata tcctgccatt tcagctcgag
    33781 tacatcaccg agccttgccg cacaaagata ggatatctcc attgcaatac gtaactgtgg
    33841 aattgcttcc gcatatattg cagcatactg ttcatcggtg atgtaaacag tacgggcttt
    33901 aagtgtgaat tttctgactc ctttgcatgg attatttttc acatacccac gctcatatcc
    33961 ccatccgtat acacggctca gacttgccag ttcatggttt gcttgggtct tgctctcaag
    34021 tcctcgctta tccatgaaaa ttcttacctg ttcaattttt acattatcag caagcacttt
    34081 tccgaatact gccaacaatg ccctttgatg ttgccgataa tctttttggg ttcggggggc
    34141 cagttctgta aatgcagggg agtccataaa catgtgccat aatttagcta ctgtcattat
    34201 gttgtggagt tttgcttttt ccagctcata attttgccag actttagcta cgctggtttc
    34261 ccgcactctt ccgagcccta tagttcttgt gcttcctttg ggtttccata cgtaactgta
    34321 accattcgat ctaacacgcg gtggtagtgc attatctttt ttgttttttc ttggtcttcc
    34381 cattgttcag cgcctcaaaa tcgggttcag cggaaaccag ttcaggtgct tttggcatcg
    34441 tagtcagtcc gtgtggaata tccctgcgaa gaactattgg ttcgttttta ggaccgatta
    34501 caaatgggat accgtgcagc cttaactggt gttgctgttt tgtgtatcgc tcgtatttcg
    34561 tgatctcttg aatctctgct ggcgatagag ttaattcgta catgtggtca cgtgccttac
    34621 agcatgaccg ccgccaatat aattcgggga cggcgatcag ggttgaacat taaaaatcaa
    34681 ccggattcgg gatcagtttt tgccagattg ctgaaacgta ttttgcctgg taacgggcgt
    34741 catcaagtgc attatggcgc tcaccttcga atggaatagc cgttctggca tcgaagtcta
    34801 tggctttccc cagctcaacg attgtgcgta catcgcgatc gttgtagtaa cgccacgggc
    34861 aggggatccc ctgccgttcg tatgaacggc gcaaaatcgt gttgtcgaag ttggctccat
    34921 ttccccagac ctgaacaaaa aattcaccgg agttttcgtc gataaattcc cgcaattgta
    34981 acagtgcatc atctaacggg atttcatcgg tcataatggc agattgcgct tcgcgtgatt
    35041 gcttaagcca ccatttaatg gtgtcccgat caatgactcc gccagcagtt tccagatcga
    35101 tagtcttact aaattccggt cccatatctc cggtttgcgg atcgaaaaat attgcaccta
    35161 ttgagataat cggggcatca ggattttttc ccatggtttc aaggtcgatc attagatggt
    35221 cacacgtcct gctggtggat gtgataacgt gatgaccgtt caccgtaatt aagggatctg
    35281 ccgtctcgcc agtttcacta tcgctggcgt gatcctgagc gctgccagca ttctctttgt
    35341 gtggatgttc agcgccttcc attttctccg aatcgtcttc ctgaacttca acctggttct
    35401 tgtcatcgaa tgtttcttgg tatgttgcgt cgcccatcac cgcaccacaa tcagggcagt
    35461 tgccgccgcc ggtctgaccg caggcggtgc agactttttc cgcttcctgt tgcgctactg
    35521 gctcaggttg tttcgtttct ggctcgtttt gtaacgcatt tgggctgttt tgttccgctt
    35581 tctggtcgtt ctgttccgtt tcttgctggt tctgattcac tgaatcgcgg gtttcaatcc
    35641 ccttcaccca tttcggatca ttcgggtcgc taatccctgc aacaaattca ccacgtgata
    35701 cagcaagcaa cttatcggcg tcaggctggg tgatattggc tgcctgcata attttgttta
    35761 cttcgtcagc ggtaactttt accggctctg gttgtgcggt cgtgtcagat gcaccagtat
    35821 tttgttgtga acctgagtat gtaccgtttt tacgggcaaa atattcttct ttcgtgattt
    35881 cagtagcccc tgcagtcagc gccttattca gaccagaaag tttgtttgcg cgaccatatt
    35941 tttcgccatc cttgtcggtg aagaggaagt agaacggccc ctcacgctct acagatggtt
    36001 cgacttccac tttgcattcg gttttttcgt tgtccggaat tgccgtttcc actgcatcag
    36061 tttctggtac tggtgacgag agagtatcag ttgcgctctg atttcttcct tcatcttcaa
    36121 acacgccctt tgtagtcagg tattcagtaa tgtatttgtt cagtgccaca gggtctttgt
    36181 gaatgtcgat cggacgttca cggacaaggc caaaaatagt ctggcggtcg tagcgaaggg
    36241 catcaggctg tttgcgcatt gatgccgaga tacgcttcca gtcttcgcgg tcgttgtcga
    36301 taacttcatt ttttgcccag cgatggatgc tgccgtcaat gtttccggca tccacatcac
    36361 caggccagag agcgtaggcc agttcgtcat ccagtgtttt ccatgtctgc ttgtattcgc
    36421 gatgagtggc agcaatgacc gggctgattt ttcctgttga attgtcagtg tactgttgat
    36481 tggctctggc gcgggcgaga tcaacaacag acgtgtattt tccggtttcc ttgcgttcac
    36541 cttcgcgacg ttttttccag atgcgcatct ctgcctgaat ttcgggccat ttagcaccag
    36601 gaatacattt atgcttaacc cacccaatgg cgtgcaactt aagctccgga tacatggcgt
    36661 taacttctgg cattttcatc aacgcttcaa cgatatgtcc gtcgaatgtt gccatgtctt
    36721 cctgcaacaa ttcctgtgcg ctaataacca tatcaacggt gatgttttca catgtgtcga
    36781 acttaaccag gaccgcgttc tgtacttcag gggacagctt gtcaaaattg acgttcatcg
    36841 gatcggattc tggttcgatc ggaataaagg aagcggattc ctcatcccag cagttttcct
    36901 gcatatattc ggtatcccag gagtcgatgg cagggcgggg catgccgggt ttatcctcgc
    36961 aaacaagaaa tttataagcg cagtcctgag cagccggata ttgctccagg aattgccagg
    37021 taaatttggc tcgggcgcgg cgttcgtcgc cggcttcaat ggcagtggct acagcgactg
    37081 caccttcttc ctttattgcc tgttcgtccg gaatggcggc gcaaataaag actttactca
    37141 ttttgtttta acctcattac agatttaagg gtgaacaaat ccctgccatt gctggcatat
    37201 aaaaatgaaa ccggatatta attacggcgc tgttttaagt cctgccggga tttcgttatt
    37261 gtccatgcga ataactttat caaccggata acagttgccg ggaattttct gttccgctgc
    37321 ggcagccatg cattctttca ttgagtcatg tataccaata acaagatcga ctggctcgcc
    37381 tgtattaaga aaaaccgtca gaacgagtgc aaatactgta ttcattgtca tcgtcctttt
    37441 tgcatcaggc gtaaacgggc cagcattgaa acaatgcata tttgatttaa tagctcccgt
    37501 tcgtgttttc tcttattaat ggcatcttca gtaaatacag ggttactgat tctgacacca
    37561 atttcaaaac aaccttcaga cgtattgacg tttggtaata acgtttccat tatcgcatcc
    37621 tcaacaatga attttgtgat gcggtgcctg gtgcctccag gtgacgttaa ccagttaata
    37681 attaacgccg gatacagaga acccacccat aagaaccaat acggaagtca actggccttt
    37741 ttaactgttc cgcgtgcgct gagccgcatt caccgcatca caaaattcac tttaaaaagg
    37801 gcgggtatca caagggaaaa caaaaaacgg atacccgcca aaaggtaatc aacatgggtt
    37861 gttgcagcgg ggttgtcact taagcgtatg gtcaacctga caacccggtg tcctcaacgg
    37921 ggaaggaata accccgccat acttaccgcc gcgccatttc gcggattgcc acaaccggaa
    37981 gcgcacagac gaagatgtca gtggtacaca acaaagggag gaatgacttc gccgtgcgct
    38041 ttcgcgttat gccctgactt ttcagggata tatcctttca gtaaactgtt tgtgccggat
    38101 tcttatccgt gtccggcgca cgaccacgcg ctgtcacgtg tggtctccat tctcaaccag
    38161 taacctcaat ggaggataaa attaaaatgg tcagcaaact aaatcagact cgctggaaga
    38221 ttcattatga aacagcgcgt ttaaattata ttcttgaatg ttttggggat aaccttgctg
    38281 ctgaggaagg ctatccaaac catgtcgatg gtttcgaagc gatatatctt tatctatccc
    38341 gtaaacatgg atggactatt tcacagtgtc gtttaatgcc actggatgat attcgccttg
    38401 ctctttcgtt agagctatca gggtggcgac tccctgatga tgcaaagatt gacgaccatc
    38461 attctcacga tgatataagt tgttaagttc cagtagtttg gcttttgcaa tgacctctac
    38521 agatttccag aatttgtggg ggtctgtact ctcttcctgt tcgtcaggaa tgttattgtc
    38581 ctcaacagaa acagaataca gtccggtaaa cgcatcgcgc acattacgag ccatattatc
    38641 aatgtctttt ttcgtttcag cttctaatgc aacttcgttc agacgttgac gaagtgtatg
    38701 tgctgcaatt tcttggattt cttttggtaa ctctttaaat tccatagtca acctcatcag
    38761 tcagtgtttc tggctaacca gcgatgcgcg ccagtttcgg ttttaaacgt tttgcttttg
    38821 gtatacgtta tcgcggtgaa cgtaccgtcc tggttgggaa acacgccgca taccagagat
    38881 tcactgttgc caagatcgat agtatccatg ttgacctcat ttccccttaa cgccggggga
    38941 gcggaacaaa aacctgctgc atagttaaag ttgaaccctg ccgtcatgtt cttacgcctc
    39001 gggctggcta cttaacccct gaccactgcc tggtaactcg aagtattgcc ctgcgttctg
    39061 tggggcgggg tgaggtggta taccataaaa ctaaatctat ttagttttat agtcaagtgt
    39121 gatctagata tatttaaaaa aggtcgacaa agccgacctc tgattgaaaa acaaagtgga
    39181 agctataggc tgaactgcac accttttgct acagcaacaa ttttacattc aggtgtcagt
    39241 aaggacgatt gatagcgagg attgaggggg cttaaataca cgagttttcc gtcgatgact
    39301 aattttttta tagtcataga tggttcgttt gtaagcggat ctgggactat tacagcgacg
    39361 atactaccat ttttatattt ttctctaggc ctcatgatca ctgtggcacc aaccggaatg
    39421 cttggcgacc ctgatgggtt gtgcatagtg tcatcaggca ttgaaacggc aaaatccccc
    39481 tccttgacgt caaagaatgt ggtgattctg tcggcatttc ccatagtttt ctctccttct
    39541 aaaattagga aagaaattgc ttccccccat gaaagatagg ggatttgggt gcctgaattg
    39601 ttctgcacaa gggtaggttc agtagacgat actccatata ggagatagga ctcagtagtt
    39661 cctagtgctt gggctaattt actaagagct ttgctaccgg gttcgtttag gtctttctcc
    39721 cagtacccta tagttacccc tgttacgcca gaaagcttgc ccagttcgac ttgggtcagt
    39781 cccttgtctt ttctgagtct cttaagccta atgccaaggc tttccatcat catctcccgt
    39841 gaattgaata taaattattt tagattgcat tgacctaaaa aaaattatcc tttaatctaa
    39901 aaatacttag ttttaggagg gtgaaatgcg agttgatgaa cttgtccagt tttttggctc
    39961 tgttcagaga gttgccgatt tttatgggat aacccgtgaa gctatataca tgtggcgcaa
    40021 acgtcctggt gaaatagttc ccaaggggag ggccgcggaa gctgccgcat actccaaggg
    40081 aaaattatct ttgaacccag aactttacaa aaagaaggat aacaccttga acgaaggaaa
    40141 gaatgattca tgaaaatcaa gcatgaacac atccgcatgg ctatgaatgc ttgggcgcgt
    40201 ccggatggtg aaaaagttcc ggcggccaag ataaccaggg cttatttcga actgggaatg
    40261 acgtccccgg aactgtacga cgacagccat ccagaagccc tggctcgtaa tacccagaaa
    40321 attttccgct gggtggagaa agacactact gatgcggttg aaaaaattca ggcgttgtta
    40381 ccagcgatcg aaaaagcaat gccacctctg ctggtggccc ggatgcgcag ccacagttca
    40441 gtctattttc gggagttggt ggagacgcgg gaacgactgg tgagagacgc tgatgatttt
    40501 gtcgcagtgg caatcgccgg tttcaatcag atgaatcgtg gtggcccggc aggaaatgct
    40561 gtggtgatgc actaaaagca cggtgttcgg ggttttttat gagcagcaag cttcatggtc
    40621 ttgtctggga agggtgcgcc ttcaccggca tgatcttatc cagggtggca gtaatggctc
    40681 gccttgcaga ctacagcaat gacgaaggtg tgtcatggcc tgcagtggag accattcgtc
    40741 gtcagattgg ggcaaagagt gaatcaacgg ttaaagcggc gatagcggaa ctggaaaaga
    40801 acggctggct gacgaaggag gagcgtaagg tcggtgggcg taatgaaagc aatatctacc
    40861 gccttaatgt ggaaaaactc gaagcagcag ctgaggcggc gcgtgaggca tataaaccga
    40921 aaagaaaaat tagcccggca aaaaatgacc cgttaacagt tgaccagtca aatattgccc
    40981 cctcaacgat tgacccgtca aattttgatg gatcaaccgt ttgtaaaaaa cagccggtta
    41041 ggggggcgat ggttggcccc gatccgtcag tattaaaacc tgatccgtca gataaaagat
    41101 cttttcgtcc ggaagcttcg caaccggacc cgcagacggc tgaacaggac tttttaaccc
    41161 gacatcctga tgcgattgtg tttagtgcaa aaaaacgtca gtggggaaat caggaggatt
    41221 tggcatgcgc acagtggatc tgggggcgaa tcgtgagtct ttacgaacag gccgccagcg
    41281 atgatggcga gatcacccga ccgaaagaac ccaactggac agcatgggcc aatgacgtgc
    41341 gcataatgcg gatgctggat ggcagaactc acagacaaat ctgcgaaatg tttggtcggg
    41401 tacagcggga tccattctgg gtaaaaaaca tcatgagtcc gtcaaaactt cgcgataaat
    41461 gggatgagct ggttatccgt ctggggcgtt cgcctgtaca gcgttgtgtg aatcatattt
    41521 ctgaaccgga caccgaaatt ccgccagggt tcaggggata agtttggttt gagattggta
    41581 aatgatttta acgggagaaa ttttgatgga aacgttgatt gatacgttaa aagcgatgca
    41641 aaaggtgacg tgcaccgagc ttgctgccag tttgggcatt gaacctgcag aggcgattaa
    41701 aatgctgagg gagtacgaag agctgggaga agttgtgtcg gttaatggtt actggtctgt
    41761 ttcagaacga caaacgggcg tgaaagaaaa aaaagtaacg gtgtgtaaag tggaaagaaa
    41821 atcccatccg gtggtcagta gaaaagagcg tgagccactg aaacgctgcg aaatcctgtc
    41881 cacacttgct catagtgggg caatgaccac cgctgagatt gcaattgctg tggggcgtgc
    41941 tgattgcgtc aggtcgctgg tttctgcgat ggaaaagctt tgccgcgatg gcatggcgat
    42001 taagctggga caggggaagg ggtgtaagtg gatgctggta aaagaaaccg gggaaaattt
    42061 accagcagag ccgaaagttg tatcggtagc gaaaacacct ggtaaagcct tttctcagtc
    42121 agccggtgtt gcgttaccag tacaggaagc ggcaacacag gaagaaatta aaacagatac
    42181 tgtgggggac attgtgcagt cgttgccatc gttcaccgaa acgcgagcga atggcctgat
    42241 tttaccatcg ctgcatatgg caagccgcga acttcgccgg gcgaaaagtc atgtccagaa
    42301 gtgggagcga gtctgcgccg cgctgcggga gctgaacaag caccgggata ttgtccgaca
    42361 gattgtcgat tcctccagtc gtattgtgtc ggaaaagtga ttccagggga gggcttatgg
    42421 caaaagtatt tacacaggaa gagcgggaaa aaattaaagg gcagattgtt gatctcgtac
    42481 gccagagcgg gcgagagacg ttacgacaac tggaagctaa aactggggca acaagatatc
    42541 tgatgagcgt tctcgcaaga gagctggttg ccagcggcga tgtatacaac tctggttacg
    42601 ggttattccc gtcagcgcag gcgcgtaagg actggcaaaa tgcccgcaaa aaactctcaa
    42661 gggcaaatct gaagaaaaca tctgtggttg atccggacct tatctggtca ttaccagacg
    42721 gagaaatacg ccgctacgac aggcgtcaga acataatctg tagcgagtgc cggaagagcg
    42781 cagctatgca gcgtgtactg gctttctatc agggtaaatt tcaggaggcg atactgtgaa
    42841 tgaaattagc tatcaggctt caattaccgc tggcattcac atcaaaggag aagagcatgg
    42901 aaataaaacc agaagatgag ttaagcaata tcgttttatt tccggtaaaa gaggatgacc
    42961 cacgtaatca ggttaatttt ctttatgagc catcggaaag agcatattgt catcacgcct
    43021 ctgttcgggt tgacgaaaaa gagcgtcagg tccgctgtaa aatctgcggt gcagttgtgg
    43081 agccgtttga ctggatgctc tctgtggcga aaagagaaac cagactggca gatgatgtaa
    43141 ggctattgcg ccaggaggaa caggaaagac ggaaaaatat agaaaagtta attcagattg
    43201 agcgtaacgc gaaagcgcgg atacgcaggg cgacaaaatc cagaactgaa taattaaatt
    43261 tagcactgta aataaaatca aatccttaac tggaggcata tctatgttaa atacacagaa
    43321 aaccattaat gcggaaaaat ataacgagtg ggtgaggaaa ttttctgagc agatttttaa
    43381 aattactggt gacgagaatg cggcaaaaaa tgaattagag ccgtggacac ctgaaggact
    43441 cgaccaaaat tattgctggt gggatgttga tccagttgat gctgcaaatg aaactatgag
    43501 ttatcacaat gattaatgtc aggaggccgc ccgaaagggc ggtaagaaat gactacatta
    43561 ttcagaaaag aatatccgag aaaaagtaga gcgacagaat ttttgtttct cattctattt
    43621 atcgtgttga tgataccgat atccccgcta ttactggtct ggtttatcgt gaaaataatt
    43681 gagccagtta ttgaattgta taacgacgtg gtgtgggcgt cgttcaacgc actgcacaat
    43741 aaaattaatc cgtataagga aagctgatat ggcactgacg aaaaaacaac gtgcagagct
    43801 gcgcatgaag ttcggcggtc gctgtgctta ttgcggctgc gaacttggcg aaaagtggca
    43861 tgcggaccat gtaaaaccgg tcattcgttt tgatggaaat atgcttcacc aggaacgtga
    43921 cgatatatcc aacatggttc cggcatgcca cccatgcaat ctgcacaagc attgcagtag
    43981 tctggaagat tatcggcgaa ttatcagtga tggtcgtcgt gaattccttg cgtccgggaa
    44041 aggcaaagcg ctggttcgta tgggattggt tgaaatgaaa tctgacccag ttgtgttctg
    44101 gtttgaaaaa tatcaagaag gggctacggc atgacgactt ttaccagaga gcagttaata
    44161 gctcacgcag aggagactat tgaagcacag agactgtgca taccgggcac aatcgaccat
    44221 gacatcatcc gcacatataa gatggatatt gctgttctgg aaatcgcact ggtatcgctg
    44281 gcagcagagc cagccggtaa attgcatgaa tacaaaccag tgggatatca gcgtctggtc
    44341 gatgagttaa ccatgctggt aaagcagtta acctggcaac tgaggaaagc gaagccagac
    44401 tgcaaattac cggataaggc gatgagttat ctggagcgga acggactgat aagcgtggag
    44461 gatattttac gatgacctgg cctgaagcat tcacaacggt aggaattgcg atggcggtgg
    44521 cgctggtggt gtattcgatt tgccgctggg gataaatcgc cgaaaaaaga tcccgacaca
    44581 aacatgagcc gggatctttg atttatatag cctacgaatc cgccagtaag agagggggcg
    44641 gacggttaat tctaacaccg gaatgatgtg ggtaaaagtt tataagaaat cggtttcata
    44701 actttgccca ccatgataga taccgacaat aaagactttt ctgctatcaa cggcaaaagc
    44761 aataatcgtt ctgtggcgga aatgagttac ccgcatcccc tggcgaatat catcgcgttt
    44821 attgccccga tgcgggaatg tagaaaaccc atcaagataa tcaagaagcg cattggcata
    44881 attgtcagca atgacgttcc ctgctttctc cgttatatac ctgtgcaggt tgattatttg
    44941 ttgttcggcc tcaggagtaa tgatgacttc atatgtcatg cagattactt cccggatcga
    45001 atcgcggcgc gaacctgtga aatggagcgt ccgttgtttg gggtttcgcg gatagaatca
    45061 agagaggggg cggctgaatg cgttaaccac gcttcgattg ctttatcgcg ctcattcagt
    45121 gcgcgaagcc cttcacgaat gacctcgctt tctgaagcat aggcaccgga agccacacgg
    45181 gcgcgcacca tgtcagccat ttcgttagtt aatgtaatgc tgaattgttg ggttgtacgc
    45241 atggtaaacc tcacggagta ggatagaaca ccattcgatg atagcacgtt gcctgttgac
    45301 gacaacagaa atcagagaca atattgccgc acgccagctt gaacaactgg cacctgctgc
    45361 gccagcagag acaaccgatg gcgcacgata ccaaattaca caattctgat gattctgccg
    45421 tctttgccag caggtgcgga cggcgttttc atgcattcaa atcggactgg ttccagcatc
    45481 caccatgcac tgaagagcag gctgaatgga taattcagtg ttaccgcagg cgcggatacg
    45541 aggttaaaaa agcccttagc ctcgactacc gtcactggat aatctccgtc aggcttcctt
    45601 actccgaacg cccaccgcgt ccgtcccgca cattccagca acgcatctgg aggtaacgtg
    45661 cgggtattac ttcgacctgt tctggtaccg gaactcgggc tggtgatagt taagccgggc
    45721 cgtgaatcca tgccggtatt ccacaatacc cgggtactgg tggagccgga accgaaaagc
    45781 atgcgtaatc tgccgtccgg ggtcgttcct gccgttcgcc agccgctggc ggaggataaa
    45841 tcattactgc catttttcag cgacgaacga gtgattcgtg ctgctggtgg cgctggtgca
    45901 ttgtctgact ggttactgcg ccatgttaaa tcctgccagt ggccacacgg cgattatcac
    45961 catagtgaaa ccgtcattca ccgttatggt accggcgcaa tggtgttgtg ctggcactgc
    46021 gacaaccagt tgcgtgacca gacctccgaa tcacttgagc aacttgctca ccaaaacttg
    46081 tcagcatgga tgattgacgt cattcgtcac gcaatgaatg gcacacagga gcgggaatta
    46141 tcgctggctg aattatcctg gtgggcggtc cgcaatcagg tggcggacgc gctaccggag
    46201 gcggtattac gtcgttcgct ggggttgcgt gcggaaaaaa tccgctcaat gtaccgtgaa
    46261 agcgacatcg taccgggaga gcagaccgcc accagcatac tgaaacagcg cacaaaaaat
    46321 cttgcgccgc tgcctcacgc ccaccagcaa cagaacccac cacaggaaaa gacggtggtc
    46381 agcattgccg ttgatcctga gtctccggaa tctttcatga aacgacctaa acgtcgccgc
    46441 tgggttaacg agaaatacac acgctgggtg aagacacagc cgtgtgcgtg ttgtggtaag
    46501 ccagccgacg atccccatca cctgattggt catggtcagg gcggaatggg gacaaaatct
    46561 cacgatattt tcacgctacc gctgtgtcgg gagcatcaca acgagcttca tgcggatccg
    46621 ctggcgttcg aagaaaagca tggttctcag gttgatttaa tttttcgttt tcttgatcac
    46681 gcctttgcaa ctggcgtgct tgggtaaaag aggtgactga tgctcataga tttggtttta
    46741 ccttacccgc cgacggtgaa cacttactgg cgacgccgtg gcagcacata ttttatctcg
    46801 gaggagggaa agcgttatcg ccgggctgtg gtgcttattg ttcgccagca gcggctgaaa
    46861 ttaagcctgt ccggaaggct ggcaataaaa attactgcag agccgccgga taagcgccgt
    46921 cgggacctgg acaatatcct gaaagcaccg ctggatgcac tgatgcatgc ggggcttctc
    46981 atagacgacg agcagtttga tgaaatcaat attgtgcgcg gtcagctcgt tcctggtggt
    47041 cggttgggga taaaaatcac agaactggag tgcgcatgaa taaccagtat ttacagtttg
    47101 tgcgtgagca gctcattatc gccaccgctg atttgagtgg ggcaacaaaa ggtcagcttg
    47161 aagcctggca ggagaatgcc atgttcgata cagggcgtta caggcgtaaa aaaatccggt
    47221 accgagatga agtgaccgga aaaatgatta cgcgggataa tccaccaatc ccggggaaac
    47281 aatcgctggc gaaggggacg tcaattcctc tggtcagtcc ggttgagttt tcgacatcat
    47341 cgtggcggcg ggctgttctg tctcttgaag aacatcataa agcctggctg ctgtggtgtt
    47401 acagcggtag catttgctgg gagcatcaga tcgcgataac gcagtgggcg tggactgaat
    47461 ttaatgctca atccggtacc agaaaaattg caggaaaaac tctggtgcgc ctgaagacgt
    47521 tgatctggtt ggcggcgcag gcggtaaaag ctgagctttt tggtggggaa ggttacgaat
    47581 accaggaact ggcgttactg gtgggagtaa caaccaaaaa ctggtccaag acatttactg
    47641 gtcactgggt tgcaatgaaa cacatttttc atcggctgga tggtgaagct ttattgttgg
    47701 tggagggaac acgttcaaaa caaaaggcgg cattttcata gcaaagtatt gcaaaagtag
    47761 ataaaaaggc atatatttcg tgtgaatctg atattttgcc gtttttatac gtgatggcaa
    47821 agctagtaaa acccgtgacc gagcgggttt ttttatcccc aaaaaaatgg catagacatt
    47881 aaacgtgatg atgattgtgc caatactttc tccatcaatg acgccccttg actgcatgga
    47941 atccaatttg ttatgtaata tgtgttgata tttttgagtt gttaatggtg ttactatgga
    48001 tgacagtgct ctgctcagaa actcttcact ttttgttgct tatatgggct gtctaggatg
    48061 gggaagcgct tatttctatg gatggggtac ttcattttac tatggctttc catggtgggt
    48121 tgtcggggct ggtgtcgatg atgtagcacg aagtttgttt tatgctgtga cagttatcgt
    48181 tatattcctt attggatggg gagttggtat tgttttcttt ttgggcataa aacaaaagcg
    48241 caatatacaa aatttgagtt ttatccggct ttttctcgcg atattgctgc tttttattcc
    48301 acctgttctg gagttttcgg taattcatca gcatgttgag ccagatgtac tgattttctg
    48361 cattcttgct gcctttacaa tcacgctttt tgtcaggttt ggaagaagac ttgtttcagt
    48421 caaatgtttt tcggaaatgt cttttattcg tcatcaccga attgagttca tgatggctgg
    48481 gtttatgatt tatttctggg cattctctct tattgccggt tggtacaaac cacagtttaa
    48541 gagggaatat caggcgatcc actatgagaa tgtatggtat tacattattg cgcgttatga
    48601 tgatcgtctg gtgttatcga aatcatacag gagtgggggt aagaaattcg ttatatttaa
    48661 tagcggaaat attaatgatt ttgaaattaa tacagtcaga gtgcgttaaa atttcttgag
    48721 taacaaagat ttttaccgcc cgccattgag aggtttttta tgccagaaaa atggttcggt
    48781 acataaaatg tgcaggtggt tattaatacc ggtctttcag cttgctggct ttttcgacaa
    48841 gagttattgg tatgtcacgt taaccaataa agagaaaaag acatgctaaa acagcaggat
    48901 atgaccgaaa cagccagagt ggtgtttaat gaattaagcg tcactgaacc ggcaacagtt
    48961 ggggaaattg cgcagaatac ttacctttca cgcgaacgct gtcagttaat actgacccag
    49021 cttgttatgg cgggtctggc agattatcag ttcggttgtt acagacgcct tccgcagtga
    49081 aggttttttc atttgtggta atgggcggct ggtgggtgtt agcggcacct gccagccatc
    49141 tgctcatgcg ttagggtcac aagcaaacct caggcccatc tgctttgcgc aaaagcggta
    49201 tgagcctatc agagaagtgc ttattgatct atggttgata ctgtaaaaat atccagttgt
    49261 gagttaatca acgctgattg cctggaattt atccagacct taccggaaaa ctctgtcgat
    49321 ctgatagtca cagacccgcc atactttaaa gtgaagcccg agggctggga taaccagtgg
    49381 aagggcgacg atgattacct gaaatggctg gatcagtgtc tggctcagtt ctggcgggta
    49441 ctgaaacctg ccggaagtct ctacctgttc tgtggtcatc gcctggcatc tgacaccgaa
    49501 atcatgatgc gtgagcgctt taatgtgctg aaccacatta tctgggcgaa gccatccgga
    49561 cgctggaacg ggtgcaacaa agaaagcctg cgggcgtatt tcccggcaac agagcgcatt
    49621 ctgtttgccg aacattatca ggggccatac cagccaaaaa atgatggcta tgcggcaaag
    49681 gagcgcgagc ttaaacaaca cgtcatggcc ccgctgattt cttacttccg tgatgcgcgt
    49741 gaatcactgg ggataacgtc caaacagata gcggaagcca ccggaaagaa aaacatggtg
    49801 tcgcactggt ttggtacctg tcagtggcag ttaccgaacg aagctgatta cagaaaactg
    49861 caggcgctgt tcgcgtgtgt tgcagaagaa aagcaccagc gtggggagct ggcaacgcca
    49921 caccagcaac tggtcagcac atacagtgaa ctgaaccggc aatatgccag tctgcttgag
    49981 gaatacaaat ctctgcggcg ttatttttct gtatcggccg ccgttcctta tacggacgtc
    50041 tggacgcata agcccgtgca gtattatccg ggtaagcatc cctgcgaaaa accggcggat
    50101 atgttgcgtc agataatttc tgccagcagt cgtccggggg atgtggttgc ggattttttt
    50161 atgggatcgg gggcaacaat aaaagcagca atgggattgg ggcgtcgcac gattggggtt
    50221 gaacttgagt ccgggcgttt tgaacaaaca gttggtgaaa tattggtgct gaacgataaa
    50281 ttgcgaaatg cacaattaga taagaacagg agctaatcct cgattaatat ctaagccaag
    50341 caggatgcta ggaagttctg atatattctg atcgtttttc gatgctttaa aatgatttgt
    50401 gctggttgcg aaagcacgtg gtcgggcact gcgttcacac atctggaggg tgtgaagcca
    50461 gcttttttgt gtgtattcag atggcgttct gattctataa cgagttacgt ggacatcagg
    50521 gatggagaga ataggaacgc catcttaata cattttcccc gtttatttga tatatcttcc
    50581 ggataaggga ttaggtctgg ttttttatgt cattcaataa cgctcttcta tactgtatac
    50641 aatactttat cctggcagtg tgtttaaaac ctgaacttat cctttgtttc gtttatagac
    50701 agaagggcta atgtcgactt atcatcagca ggatggcaat agatgtgtaa gtagctggtc
    50761 accagctata cttcagtggt acttctgagt gcttctctcc gtgaaatgat tatcatccag
    50821 atggcaggag tagagtgaat attgatgata tttccaggtg ctccagcttg ttgcagcgta
    50881 ttgaggatgt taatgctgaa cgagccaggg cctttagtcg tttgacagtt atattttcta
    50941 cccttgatcg cctttcagga aagaacattg ttttattaaa cagtgatgcc atccataagg
    51001 tttttgaaga gttcatggct gctaattcag aattgctggc tcttgttgag gaatacaacg
    51061 agatagccag ccgtgtcggt atggatgaat tcaacgtcat acttcgtgga taaaaacatg
    51121 cttcatattt tctgttagct cgctactgcg agcttttttg tatctgagcc acatcaggcg
    51181 cacatcaaaa acacagagcc tttcagggcg gggagggggg tcttgccgtt acaccgtaat
    51241 gcaaaataac agcatacaaa aggtatcggt gatggttgtt attggtgtgg tttattaaaa
    51301 aagtgtaaga aaattatgag cgttgtagtt gaacaaaatg gtgaaattgt atgagctcgg
    51361 cataatgaaa gttctgaagg tattgcctgc acacgctgtg taaaggacgg cacgcaactg
    51421 cgactcgttg ccgtccttga ggacgcattt actcaggcta aaggcgagtt gctatgctgg
    51481 gatgacggaa atggagtgcc gaatagctgc acttccgcct cctaaatcaa ttgtaatatt
    51541 ccagtaacct gaatgcggta catgaaggtg ggccggtaat ctctgaaaaa aaccgccacc
    51601 accgtgatga tgaaagcttc ttgcgttgcg gtagttatta aagtttgtat ctgtcatcag
    51661 caaaatattg cactgatgag agcagtcaac cactaccgta tctcctgcat ttaaatgcat
    51721 tcttttatgt aaaaactgca tgtgatttcc ctgatcagag gtaatcagcc atccctcttt
    51781 ctctatgatg agccagcgtc ccaccactgg cgggctgaat gcttaacata tccagggttc
    51841 agaaaacggt aaaccctgat aaatatccat atcttcaaac gttaataaaa tgtcagttac
    51901 ggggccgctg atggtccttt ttatttacag gagaataaat atgtctgaac ccttatccgg
    51961 ttccagcact gctgtggcgc tcggcggggc gacggtattc gggctgttta ccgggacgga
    52021 tttcgggatt gtgtttggcg cgtttgccgg ggcgttgttt gtggccacga tgccacaggt
    52081 gatttctgtc tggcgtgtgg cggcgcattt tctggtgtcg ttcattgttg gcgtgctggg
    52141 ggcggatgtc cttgcgtcct ggctggtcga aaaattgaat ctccacagca catctctcga
    52201 cgcgctttgt gcggtactgg tatcggtggt gtcggtgaag attctctcat tcatccacca
    52261 gcaggatatc gcatcgctgg tatccgggct gttctcccgt ctgcggggtg gaggcggtaa
    52321 tgttaagtaa ccttcccgga ttactgaatg tggtgttaag cacggttatc gtgctgacgc
    52381 tcttttttta tcgtcgtggt gagtcgagac ataaaccgct gatgtcgtgg ctggcctggc
    52441 tgctgatgct gctttatgcc tttgcgccgc tttgttatct gtgtggtcgc tttccacccg
    52501 gtaactggct ggtcgtcctg attaacctgg tgttctgcgt gctggtgata cgagcacgcg
    52561 ggaacgtatc aaaaatcctt gtattacgaa ggcgctgata tgaagtcgaa agatgaaatt
    52621 tttgacgaaa ttctgggaaa agagggcggt tacgtcaatc acccggatga taaaggtggt
    52681 ccgactaaat ggggcatcac tgaaaaagtt gcccgtgcac acggttatca gggcgatatg
    52741 cgtgacctga cgcgtgggca ggcgctggaa atactcgagg cggactactg gtacggacca
    52801 cgattcgacc aggttgagga cctgtctccg gatattgccg cagagttgtg cgatacgggc
    52861 gtgaacatgg ggccaactgt ggcgtccaga atgcttcagc gctggctgaa cgttttcaac
    52921 ctgcgcggga aactctatcc ggatatggat gctgatggac gcatcgggcc gcgtactctt
    52981 aatgcattac gggcatatct gaaaaatcgc agcagggatg gtgaactggt actggtgaaa
    53041 gccctgaact gtacgcaggg cgagcgttat ctggagctgg cagagaaacg cgaggccaat
    53101 gagtcgtttg tctatggctg gatgaaagag cgcgtggtgg tttaaaaact gacactgaag
    53161 tgctgaacac cctcaactca tgcaggctct tttctggggc tacgatgagc gaaagtaagg
    53221 ggcatagcat cagatagcaa aaaccccggc tgcggtaaca gtccggggtt ttctgtttct
    53281 ggccttgggt aaggcaaagg agaacatgag gaagtataaa ctaattctgt tgaggttgac
    53341 tatgaaaaac ggccttgaat tgaaagcgcc tgtaactgat gacatcagca gagcggtggc
    53401 ttttgccatt aagtgggtgg cggtcggtat cgctgtgtct ccgatgctgt atgggatggc
    53461 aaaattgctc attgctgtga aatcgtaagt ggggcagggg taaatatgtc agatagcatt
    53521 ataaaactgg cgcgaattct ctgtgtggtt gttggccttt cattttcagc aatgttggtt
    53581 gccattttca tttccaccgc ctggcgagta ttgagcttat ccggattgat tggtggatag
    53641 tgagatgaag cgaaaacact ggacacacag aatgccgcga acggcggcga aatgggcact
    53701 ggtagcgata ctggtgcctt ttttcctggt gggatgcgtc agcctggata aggcgcgcca
    53761 gcttttcgat acagcttctc aggtctgtgg aattgtcgac ggtgttcggc agtgtatgca
    53821 gaactgatcg cctgtaagag cagaatattg ttgaatctaa atttactttg aacagtggcc
    53881 cggatggaaa gggcatctaa ataggagcag aaaaatgtta actgtaaaag tcatgtctca
    53941 aaatggtggg gaagagatcc attgcgggcg tagcattggc tatcatcctg agcagcggag
    54001 tattgccgta tcgggaaagg atgggaaagt cattctgaaa gatggagata ttgcttatgt
    54061 aatgaaccaa aacgctcaaa taatatctgt ttatcggccc aataatagtc agaaaaacat
    54121 ttgaatttcg caaggccaaa gttcagtggt gatcgttatc aactaattga aataacaagc
    54181 ttatgtttgt gtaattggtg atatagcatg ttaatgctga atatcagcgt caacatggag
    54241 ttatacaatg gtttttaaac actattacgt gaacaaaaat gctcagagca atggcgatca
    54301 tgaggtgcat gctgaggaat gttcatatct tcctgctgta gctaaccgcg attaccttgg
    54361 ttactatagt gattgttctt cggcggtaac agaggcaaag gccaaaggat attcccgggt
    54421 gaatggttgc tattggtgtg ccaataagtg ccacacgtct taatcaattg tcaataaacc
    54481 ataaaggccg ctctgcggcc tttttcatgt taaaaaagat tgcggcatta cagcagccct
    54541 tcactctaag gggctgctgt aatgtgagaa ataaaaaacc ggtccagcta cacagaaccg
    54601 gccggcgaag accgccaata ccacccatgc attgatgcaa catactaatg acaatagccg
    54661 ctattgatgt aaatgcaatg ttatgcatcg acgaaaataa aaaaccggca ggggaaatcc
    54721 attgaagatt tgccggtggc aaaagagggc catgctttta accttagtcg cagagttacg
    54781 gagtgcaaca acgaccgtcg ccgttatctt gctgaaaggc gtttcaatga ttttcatcaa
    54841 tttattcatc agcaatggtg ataatcactc tcatttgtgc gggtccttcc ggtggggtgg
    54901 cctgccacgg ggcggcgacc tcgcgggttt tcgctattta cgagtttttt tgaggtgatg
    54961 gttgttgttt tatcgtttga tatatctact tgataagtaa taagaaagaa aaataaacac
    55021 aacaacctga tgatctttct tatacgaaaa agcatgtaaa atcagagggt tttacaaaaa
    55081 acgtggttgt tgtattgctt ttttgccggt ggtttatgga ggggctgtgg cctttttatt
    55141 gaataaaagc gacatggcct cctccatcgg tatctcagta caggcatttg ataaatgggg
    55201 tgttcctcct gttgagcgcc gggggagaga ggttttctat gacgttaaaa ctgtactgga
    55261 gatagatcgc gagcgacgtc aacaaaacca gaaatcttca ggtggtgaaa atgatcttga
    55321 ggaaaggcta cttcaggcca gggttaacct gacggaagaa caggctattg ctcagcggtt
    55381 aaaaaaccag gttgcagagc ataaggtgat tgatacagct ttctctattt ttgccctgtc
    55441 tcggttatcc ggagaactgg catctgtttt ggacagtatt ccgctttcga tgcaaagaaa
    55501 attccctgaa ttgacaggca gacaattggc ttatctaaaa gagctggttg cgaagggggc
    55561 taataaatgc gttgagtccg ctgaaaaaat gaaggaattt gcggatgagt attacagaaa
    55621 tacagatgaa taatttcgta ttggcagtga aggcgggtct ctcagtcctg aaaagaccat
    55681 tgccaatgac ccccgttgaa tgggcggatg ccaattacta tctcccaaaa gaatccgcat
    55741 accaggaagg gcgctgggaa acactgccct ttcagcgggc catcatgaat gcgatgggca
    55801 gcgactacat ccgtgaggtg aatgtggtga agtctgcccg tgtcggttat tccaaaatgc
    55861 tgctgggtgt ttatgcctac ttcatagagc ataagcagcg caacaccctt atctggttgc
    55921 cgacggatgg tgatgccgag aactttatga aaacccacgt tgagccgact attcgtgata
    55981 ttccgtcgct gctggcgctg gccccgtggt atggcaaaaa gcaccgggat aacacgctca
    56041 ccatgaagcg tttcactaat gggcgtggct tctggtgcct gggcggtaaa gcggcaaaaa
    56101 actaccgtga aaagtcggtg gatgtggcgg gttatgatga acttgctgct tttgatgatg
    56161 atattgaaca ggaaggctct ccgacgttcc tgggtgacaa gcgtattgaa ggctcggtct
    56221 ggccaaagtc catccgtggc tccacgccca aagtgagagg cacctgtcag attgagcgtg
    56281 cagccagtga atccccgcat tttatgcgtt ttcatgttgc ctgcccgcac tgcggggagg
    56341 agcagtacct taaatttggc gataaagaga cgccgtttgg cctcaaatgg acgccggatg
    56401 atccctccag cgtgttttat ctctgcgaac ataatgcctg cgtcatccgc cagcaggagc
    56461 tggacttcac tgatgcccgt tatatctgcg aaaagaccgg gatctggacc cgtgatggca
    56521 ttctctggtt ttcgtcatcc ggtgaagaga ttgaaccgcc tgacagcgtg acctttcaca
    56581 tctggacggc gtacagcccg ttcaccacct gggtgcagat tgtcaaagac tggatgaaga
    56641 cgaaagggga tacgggaaaa cgtaaaacct tcgtgaacac cacgctcggt gagacgtggg
    56701 aggcgaaaat tggcgaacgt ccggatgctg aagtgatggc agagcggaaa gagcattatt
    56761 cagcgcccgt tcctgaccgt gtggcttacc tgactgccgg tatcgactcc cagctggacc
    56821 gctacgaaat gcgcgtatgg ggatgggggc cgggtgagga aagctggctg attgaccggc
    56881 agattattat gggtcgccac gacgatgaac agacgctgct gcgtgtggat gaggccatca
    56941 ataaaaccta tacccgccgg aatggtgcag aaatgtcggt atcccgtatc tgctgggata
    57001 ctggcgggat tgacccgacc attgtgtatg aacgctcgaa aaaacatggg ctgttccggg
    57061 tgatccccat taaaggggca tccgtctacg gaaagccggt ggccagcatg ccacgtaagc
    57121 gaaacaaaaa cggggtttac cttaccgaaa tcggtacgga taccgcgaaa gagcagattt
    57181 ataaccgctt cacactgacg ccggaagggg atgaaccgct tcccggtgcc gttcacttcc
    57241 cgaataaccc ggatattttt gatctgaccg aagcgcagca gctgactgct gaagagcagg
    57301 tcgaaaaatg ggtggatggc aggaaaaaaa tactgtggga cagcaaaaag cgacgcaatg
    57361 aggcgctcga ctgcttcgtt tatgcgctgg cggcgctgcg catcagtatt tcccgctggc
    57421 agctggatct cagtgcactg ctggcgagcc tgcaggaaga ggatggtgca gcaaccaaca
    57481 agaaaacact ggcagattac gcccgtgcct tatccggaga ggatgaatga cgcgacagga
    57541 agaacttgcc gctgcccgtg cggcactgca tgacctgatg acaggtaaac gggtggcaac
    57601 ggtacagaaa gacggacggc gagtggagtt tacggccact tccgtgtctg acctgaaaaa
    57661 atacattgcg gagcttgagg tgcagaccgg catgacacag cgacgcaggg gacctgcagg
    57721 attttatgta tgaaaacgcc caccattccc acccttctgg gaccggacgg catgacatcg
    57781 ctgcgtgaat atgccggtta tcacggcggt ggcagcggat ttggtgggca gttgcgggcg
    57841 tggaacccac cgggtgaaag tgtggatgca gccctgctgc ccaactttac ccgtggcaat
    57901 gcccgcgcgg acgatctggt acgcaataac ggctatgctg ccaacgccat ccagctgcat
    57961 caggatcata tcgtcgggtc ttttttccgg ctcagtcatc gcccaagctg gcgctatctg
    58021 ggcatcgggg aggaagaagc ccgtgccttt tcccgcgagg ttgaagcggc atggaaagag
    58081 tttgccgagg acgactgttg ctgcattgac gttgagcgaa aacgcacgtt caccatgatg
    58141 attcgggaag gtgtggccat gcatgccttt aacggtgaac tgttcgttca ggccacctgg
    58201 gataccagcc cgtcgcgact gttccggaca cagttccgga tggtcagccc gaagcgcatc
    58261 agcaacccga acaataccgg cgacagccgg aactgccgtg ccggtgtgca gattaatgac
    58321 agcggtgcgg cgctgggata ttacgtcagc gaggacgggt atcctggctg gatgccgcag
    58381 aaatggacat ggataccccg tgagttaccc ggcgggcgcg cctcgttcat tcacgttttt
    58441 gaacccgtgg aggacgggca gacccgcggt gcaaatgtgt tttacagcgt gatggagcag
    58501 atgaagatgc tcgacacgct gcagaacacg cagctgcaga gcgccattgt gaaggcgatg
    58561 tatgccgcca ccattgaaag tgagctggat acgcagtcag cgatggattt tattctgggc
    58621 gcgaacagtc aggagcagcg ggaaaggctg acgggctgga ttggtgaaat tgccgcgtat
    58681 tacgccgcag caccggtccg tctgggaggc gcaaaagtgc cgcacctgat gccgggggac
    58741 tcactgaacc tgcagacggc tcaggatacg gataacggct actccgtgtt tgagcagtca
    58801 ctgttgcggt atatcgctgc cgggctgggt gtctcgtatg agcagctttc ccggaattac
    58861 gcccagatga gctactccac ggcacgggcc agtgcgaacg agtcgtgggc gtactttatg
    58921 gggcggcgaa aattcgtcgc atcccgtcag gcgagccaga tgtttctgtg ctggcttgaa
    58981 gaggccatcg ttcgccgcgt ggtgacgtta ccttcaaaag cgcgcttcag ctttcaggaa
    59041 gcccgcagtg cctgggggaa ctgcgactgg ataggctccg gtcgtatggc catcgatggt
    59101 ctgaaagaag ttcaggaagc ggtgatgctg atagaagccg gactgagcac ctacgagaaa
    59161 gagtgcgcga aacgcggtga cgactatcag gaaatttttg cccagcaggt ccgtgaaacg
    59221 atggagcgcc gcgcagctgg tcttaaacca cccgcctggg cggctgcggc atttgaatcc
    59281 gggctgcgac aatcaacaga ggaggagaag agtgacagca gagctgcgta atctcccgca
    59341 tattgccagc atggccttta atgagccgct gatgcttgaa cccgcctatg cgcgggtttt
    59401 cttttgtgcg cttgcaggcc agcttgggat cagccgcctg acggatgcag tatccggtga
    59461 cagcctgact gccggagagg cacccgcgac gctggcgtta tccgttaatg atgacggacc
    59521 acgacaggcc cgcagttatc aggtcatgaa cggcatcgcc gtgctgccgg tgtccggcac
    59581 gctggtcagc cggacgcggg cgctgcagcc gtattcgggg atgaccggtt acaacggcat
    59641 tatcgcccgt ctgcaacagg ctgccagtga cccgatggtg gacggcattc tgctggatat
    59701 ggacacgccc ggcggaatgg tggcaggggc atttgactgc gctgacatca tcgcccgtgt
    59761 gcgtgacata aagccggtat gggcgctggc caatgacatg aactgcagcg caggtcagct
    59821 gcttgccagt gccgcctccc ggcgtctggt cacgcagacc gcccggacag gctccatcgg
    59881 cgtcatgatg gctcacagta attacggtgc tgcgctggag aaacagggcg tggaaatcac
    59941 gctgatttac agcggcagcc ataaggtgga tggcaacccc tacagccatc ttccggatga
    60001 cgtccgggag acactgcagt cccggatgga tgcaacccgc cggatgtttg cacagaaggt
    60061 gtcggcatat accggcctgt ccgtgcaggc tgtgctggat accgaggctg cagtgtacag
    60121 cggtcaggag gccattgatg ccggactggc tgatgaactt gtcaacagca ccgatgcgat
    60181 caccgtcatg cgtgatgcac tggatacacg taaatcccgt ctctcaggag ggcgaatgac
    60241 caaagagact caatcaacaa ctgtttcagc cactgcttcg caggctgacg ttactgacgt
    60301 ggtgcaagcg acggagggca aaaatgccag cgcggcgcag ccggatgtga acgcgcagat
    60361 caccgcagcg gttgcggcag aaaacagccg cattatgggg atcctcaact gtgaggaggc
    60421 tcacggacgc gaagaacagg cacgcgtgct ggccgaaacc cccggtatga ccgtggaaac
    60481 ggcccgccgc attctggcag ctgcaccaca gagtgcacag gcgcgcagtg acactgcgct
    60541 ggatcgtctg atgcaggggg caccggcacc gctggctgca ggtaacccgg catctgatgc
    60601 cgttaacgat ttgctgaaca caccagtgta agggatgttt atgacgagca aagaaacctt
    60661 tacccattac cagccgctgg gcaacagtga cccggcacat acggcaaccg cgcccggcgg
    60721 attgagtgcg aaagcgcctg caatgacccc gctgatgctg gacaccgcca cccgtaagct
    60781 ggttgtgtgg gatggcacca ccgacggtgc tgccgttggc attctggcgg ttgctgctga
    60841 ccagaccagc accacgctga cgttctacaa gtccggcacg ttccgttatg aggatgtgct
    60901 ctggccggag gctgccagcg acgagacgaa aaaacggacc gcgtttgccg gaacggcaat
    60961 cagcatcgtt taaccttacc cttcatcact aaaggccgcc tgtgcggctt tttttacggg
    61021 atttttttat gtcgatgtac acaaccgccc agctgctggc ggcaaatgag cagaaattta
    61081 agtttgatcc gctgtttctg cgtctctttt tccgtgagag ctatcccttc accacggaga
    61141 aagtctatct ctcacaaatt ccgggactgg taaacatggc gctgtacgtt tcgccgattg
    61201 tttccggtga ggttatccgc tcccgtggcg gctccacctc tgaatttaca ccgggatatg
    61261 tcaagcccaa gcatgaggtg aatccgcaga tgaccctgcg tcgcctgccg gatgaagatc
    61321 cacagaatct ggcggacccg gcttaccgcc gccgtcgcat cattctgcag aacatgcgag
    61381 acgaagagct ggccattgct caggtcgaag agatgcaggc agtttctgcc gtgcttaagg
    61441 gcaaatacac catgaccggt gaagccttcg atccggttga agtggatatg gggcgcagtg
    61501 aggcaaataa catcacgcag tccggcggta cggagtggag caagcgtgac aagtccacgt
    61561 atgacccgac cgacgatatc gaagcctacg cgctgaacgc cagcggtgtg gtgaatatca
    61621 tcgtgtttga tccgaaaggc tgggcgctgt tccgttcctt caaagccgtc aaggagaagc
    61681 tggatacccg tcgcggctct cattccgaac tggagacagc ggtaaaagac ctgggcgaag
    61741 cggtgtccta taaggggatg tatggcgata cggcgatcgt cgtgtattcc ggacagtacg
    61801 tggaaaacga cgtcaaaaag aacttcctgc cggacaacac gatggtgctg gggaacactc
    61861 aggcacgcgg tctgcgcacc tatggctgca ttcaggatgc ggacgcacag cgcgaaggta
    61921 ttaacgcctc tgcccgctac ccgaaaaact gggtgaccac cggcgatccg gcgcgtgagt
    61981 tcaccatgat tcagtcagca ccgctgatgc tgctggctga ccctgatgcg ttcgtgtccg
    62041 tacaactggc gtaatcatgg cccttcgggg ccattttctc tctgtggagg agtccatgac
    62101 gaaagatgaa ctgattgccc gtcttcaggt gctgggtgag caactgaacc gtgatgtcag
    62161 cctgatgggg acgaaagaag aactggtgct ccgtgtggca gagctggaag aggagcttga
    62221 tgacacggat gacgctgccg gtcaggacac atctgtcagc ccggaaaatg cgctgaccgg
    62281 acatgaaaat gaggtggtat cagcgcagcc ggataccgtg attgatacgg ctgctctggt
    62341 cacggtcgtg gcactggtga cgctgcatac tgatgcactt cacgccacgc gggatgagcc
    62401 tgtggcattt gtgctgccgg gaacggcgtt tcgtgtctct gccggtgtgg cagccgaaat
    62461 gacagaacat ggcctggcca gaatgcaata acgggaggcg ctgtggctga ttccgataac
    62521 ctgttcgatg ctgccattgc ccgcgccgat gaaacgatac gcgggtacat gggaacgtca
    62581 gccaccatga catccggtga gctgtccggt gctgtgatac gtggtgtttt tgatgaccct
    62641 gaaaatatca gctatgccgg acagggggtg cgcgttgaag gctccagccc gtccctgttt
    62701 gtccggactg atgatgtgcg gcagctgcgg cgtggagaca cactgaccat cggcgaggaa
    62761 aacttctggg tggaccggat ttcgccggat gatggcggaa gctgtcatct ctggcttggg
    62821 cgtggcgtgc cgcctgccgt taaccgtcgc cgctgaaagg gggatgtatg gccataaaag
    62881 gtcttgagca ggccgttgaa aacctcagcc gtatcagcaa aacggcggtg cctggtgccg
    62941 ccgcaatggc cattaaccgc gttgcgtcat ccgcgatatc gcagtctgcg tcacaggttg
    63001 cccgtgagac aaaggtacgc cggaaactgg taaaggaaag ggccaggctg aaaagggcca
    63061 cggtcaaaaa tccgcaggcc agaatcaggg ttaaccgggg ggatttgccc gtaatcaagc
    63121 tgggtaatgc gcgggttgtc ctttcgcgcc gcaggcgtcg taaaaagggg cagcgttcat
    63181 ccctgaaagg tggcggcagc gtgcttgtgg tgggtaaccg tcgtattccc ggcgcgttta
    63241 ttcagcaact gaaaaacggc cggtggcatg ttatgcagcg tgtggccggg aaaaaccgtt
    63301 accccattga tgtggtgaaa atcccgatgg cggtgccgct
//
LOCUS       DAPHKZ010000014        58975 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.014, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000014 DAPHKZ010000000
VERSION     DAPHKZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 58975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58975
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.014"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            120..2654
                     /gene="mrcB"
                     /locus_tag="RH288_000932"
     CDS             120..2654
                     /gene="mrcB"
                     /locus_tag="RH288_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HDV4030021.1"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     gene            2874..5117
                     /gene="fhuA"
                     /locus_tag="RH288_000933"
     CDS             2874..5117
                     /gene="fhuA"
                     /locus_tag="RH288_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
                     /protein_id="HDV4030022.1"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLD
                     DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
                     FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
                     QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLNLYNPVNTDFDFNAKDP
                     ANSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
                     FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
                     IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
                     DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
                     FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
                     ATATFRF"
     gene            5168..5965
                     /gene="fhuC"
                     /locus_tag="RH288_000934"
     CDS             5168..5965
                     /gene="fhuC"
                     /locus_tag="RH288_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HDV4030023.1"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     gene            5965..6855
                     /gene="fhuD"
                     /locus_tag="RH288_000935"
     CDS             5965..6855
                     /gene="fhuD"
                     /locus_tag="RH288_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HDV4030024.1"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAEMHLAQYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRVLDNAIGGKA"
     gene            6852..8834
                     /gene="fhuB"
                     /locus_tag="RH288_000936"
     CDS             6852..8834
                     /gene="fhuB"
                     /locus_tag="RH288_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HDV4030025.1"
                     /translation="MSKRIALFPALLLALLVIVATALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVAAERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     gene            complement(8992..10272)
                     /gene="hemL"
                     /locus_tag="RH288_000937"
     CDS             complement(8992..10272)
                     /gene="hemL"
                     /locus_tag="RH288_000937"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HDV4030026.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     gene            10497..11918
                     /gene="clcA"
                     /locus_tag="RH288_000938"
     CDS             10497..11918
                     /gene="clcA"
                     /locus_tag="RH288_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HDV4030027.1"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     gene            11942..12007
                     /locus_tag="RH288_000939"
     CDS             11942..12007
                     /locus_tag="RH288_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030028.1"
                     /translation="MAIIIGLEFAQLPMSFGAKYE"
     gene            12000..12344
                     /gene="erpA"
                     /locus_tag="RH288_000940"
     CDS             12000..12344
                     /gene="erpA"
                     /locus_tag="RH288_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HDV4030029.1"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(12391..13014)
                     /locus_tag="RH288_000941"
     CDS             complement(12391..13014)
                     /locus_tag="RH288_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HDV4030030.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     gene            complement(13052..13852)
                     /gene="btuF"
                     /locus_tag="RH288_000942"
     CDS             complement(13052..13852)
                     /gene="btuF"
                     /locus_tag="RH288_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HDV4030031.1"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     gene            complement(13845..14543)
                     /gene="mtnN"
                     /locus_tag="RH288_000943"
     CDS             complement(13845..14543)
                     /gene="mtnN"
                     /locus_tag="RH288_000943"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDV4030032.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     gene            14627..16144
                     /gene="dgt"
                     /locus_tag="RH288_000944"
     CDS             14627..16144
                     /gene="dgt"
                     /locus_tag="RH288_000944"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HDV4030033.1"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            16274..17698
                     /gene="degP"
                     /locus_tag="RH288_000945"
     CDS             16274..17698
                     /gene="degP"
                     /locus_tag="RH288_000945"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HDV4030034.1"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSS
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     gene            17853..19010
                     /gene="cdaR"
                     /locus_tag="RH288_000946"
     CDS             17853..19010
                     /gene="cdaR"
                     /locus_tag="RH288_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414704.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HDV4030035.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKTMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     gene            complement(19099..19485)
                     /locus_tag="RH288_000947"
     CDS             complement(19099..19485)
                     /locus_tag="RH288_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HDV4030036.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     gene            complement(19647..20459)
                     /gene="yaeI"
                     /locus_tag="RH288_000948"
     CDS             complement(19647..20459)
                     /gene="yaeI"
                     /locus_tag="RH288_000948"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414706.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase YaeI"
                     /protein_id="HDV4030037.1"
                     /translation="MISRRRFLQATAATIATSSGFGYMHYCEPGWFELIRHRLAFFKD
                     NAAPFKILFLADLHYSRFVPLSLISDAIALGIEQKPDLILLGGDYVLFDMSLNFSAFS
                     DVLSPLAECAPTFACFGNHDRPVGTEKNHLIGETLKSAGITVLFNQATVIATPNRQFE
                     LVGTGDLWAGQCKPPPASEANLPRLVLAHNPDSKEVMRDEPWDLMLCGHTHGGQLRVP
                     LVGEPFAPVEDKRYVAGLNAFGERHIYTTRGVGSLYGLRLNCRPEVTMLELV"
     gene            complement(20513..21337)
                     /gene="dapD"
                     /locus_tag="RH288_000949"
     CDS             complement(20513..21337)
                     /gene="dapD"
                     /locus_tag="RH288_000949"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HDV4030038.1"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(21368..24040)
                     /gene="glnD"
                     /locus_tag="RH288_000950"
     CDS             complement(21368..24040)
                     /gene="glnD"
                     /locus_tag="RH288_000950"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HDV4030039.1"
                     /translation="MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDVDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVHNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGNPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     gene            complement(24102..24896)
                     /gene="map"
                     /locus_tag="RH288_000951"
     CDS             complement(24102..24896)
                     /gene="map"
                     /locus_tag="RH288_000951"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDV4030040.1"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     gene            25264..25989
                     /gene="rpsB"
                     /locus_tag="RH288_000952"
     CDS             25264..25989
                     /gene="rpsB"
                     /locus_tag="RH288_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDV4030041.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            26247..27098
                     /gene="tsf"
                     /locus_tag="RH288_000953"
     CDS             26247..27098
                     /gene="tsf"
                     /locus_tag="RH288_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDV4030042.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            27245..27970
                     /gene="pyrH"
                     /locus_tag="RH288_000954"
     CDS             27245..27970
                     /gene="pyrH"
                     /locus_tag="RH288_000954"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDV4030043.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            28262..28819
                     /gene="frr"
                     /locus_tag="RH288_000955"
     CDS             28262..28819
                     /gene="frr"
                     /locus_tag="RH288_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDV4030044.1"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     gene            28911..30107
                     /gene="ispC"
                     /locus_tag="RH288_000956"
     CDS             28911..30107
                     /gene="ispC"
                     /locus_tag="RH288_000956"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDV4030045.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     gene            30296..31054
                     /gene="ispU"
                     /locus_tag="RH288_000957"
                     /gene_synonym="uppS"
     CDS             30296..31054
                     /gene="ispU"
                     /locus_tag="RH288_000957"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HDV4030046.1"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     gene            31067..31924
                     /gene="cdsA"
                     /locus_tag="RH288_000958"
     CDS             31067..31924
                     /gene="cdsA"
                     /locus_tag="RH288_000958"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414717.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDV4030047.1"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            31936..33288
                     /gene="rseP"
                     /locus_tag="RH288_000959"
     CDS             31936..33288
                     /gene="rseP"
                     /locus_tag="RH288_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HDV4030048.1"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            33318..35750
                     /gene="bamA"
                     /locus_tag="RH288_000960"
     CDS             33318..35750
                     /gene="bamA"
                     /locus_tag="RH288_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HDV4030049.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     gene            35872..36357
                     /gene="skp"
                     /locus_tag="RH288_000961"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             35872..36357
                     /gene="skp"
                     /locus_tag="RH288_000961"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HDV4030050.1"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     gene            36361..37386
                     /gene="lpxD"
                     /locus_tag="RH288_000962"
     CDS             36361..37386
                     /gene="lpxD"
                     /locus_tag="RH288_000962"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HDV4030051.1"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     gene            37491..37946
                     /gene="fabZ"
                     /locus_tag="RH288_000963"
     CDS             37491..37946
                     /gene="fabZ"
                     /locus_tag="RH288_000963"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDV4030052.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            37950..38738
                     /gene="lpxA"
                     /locus_tag="RH288_000964"
     CDS             37950..38738
                     /gene="lpxA"
                     /locus_tag="RH288_000964"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HDV4030053.1"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     gene            38738..39886
                     /gene="lpxB"
                     /locus_tag="RH288_000965"
     CDS             38738..39886
                     /gene="lpxB"
                     /locus_tag="RH288_000965"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HDV4030054.1"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKEHVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     gene            39883..40479
                     /gene="rnhB"
                     /locus_tag="RH288_000966"
     CDS             39883..40479
                     /gene="rnhB"
                     /locus_tag="RH288_000966"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDV4030055.1"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     gene            40516..43998
                     /gene="dnaE"
                     /locus_tag="RH288_000967"
     CDS             40516..43998
                     /gene="dnaE"
                     /locus_tag="RH288_000967"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDV4030056.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLETELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            44011..44970
                     /gene="accA"
                     /locus_tag="RH288_000968"
     CDS             44011..44970
                     /gene="accA"
                     /locus_tag="RH288_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDV4030057.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     gene            45069..47210
                     /gene="ldcC"
                     /locus_tag="RH288_000969"
     CDS             45069..47210
                     /gene="ldcC"
                     /locus_tag="RH288_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HDV4030058.1"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWF
                     FDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     gene            47267..47656
                     /locus_tag="RH288_000970"
     CDS             47267..47656
                     /locus_tag="RH288_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414729.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDV4030059.1"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCET
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     gene            47721..49019
                     /gene="tilS"
                     /locus_tag="RH288_000971"
     CDS             47721..49019
                     /gene="tilS"
                     /locus_tag="RH288_000971"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDV4030060.1"
                     /translation="MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGVAL
                     RAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELVQWARQYDLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQSPQGTLQIVPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSENIVPWQTWLQPLELPA
                     GLGSVQLNAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAEGENGVSFVWQKTLS"
     gene            complement(49068..49328)
                     /gene="rof"
                     /locus_tag="RH288_000972"
     CDS             complement(49068..49328)
                     /gene="rof"
                     /locus_tag="RH288_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HDV4030061.1"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES"
     gene            complement(49315..49515)
                     /locus_tag="RH288_000973"
     CDS             complement(49315..49515)
                     /locus_tag="RH288_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HDV4030062.1"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     gene            49681..50226
                     /locus_tag="RH288_000974"
     CDS             49681..50226
                     /locus_tag="RH288_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HDV4030063.1"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFTYNSRAAQIWWQQNQSKCVQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTAWQQPS"
     gene            50223..50645
                     /gene="arfB"
                     /locus_tag="RH288_000975"
     CDS             50223..50645
                     /gene="arfB"
                     /locus_tag="RH288_000975"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDV4030064.1"
                     /translation="MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAMIKELTTEK
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     gene            50659..51369
                     /gene="nlpE"
                     /locus_tag="RH288_000976"
                     /gene_synonym="cutF"
     CDS             50659..51369
                     /gene="nlpE"
                     /locus_tag="RH288_000976"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414734.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HDV4030065.1"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEAAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERSYLAARGHSEKPVLLSVEGHFTLEGNPDTGAPTKVLA
                     PDTAGKFYPNQDCSSLGQ"
     gene            complement(51569..52393)
                     /locus_tag="RH288_000977"
     CDS             complement(51569..52393)
                     /locus_tag="RH288_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414735.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeF family permuted papain-like enzyme"
                     /protein_id="HDV4030066.1"
                     /translation="MDKPKAYCRLFLPSFLLLSACTVDISQPDPSATAVDAEAKTWAV
                     KFQHQSSFTEQSIKEITAPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIFLGDNN
                     VAEATGAGVQIVSLKKAMKHSDKLFVLRVPDLTPQQATDITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSSVGEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRIGDVSAFKPETQLQYVGHLKPGIYIKAGRFVGLTR"
     gene            complement(52447..54165)
                     /gene="proS"
                     /locus_tag="RH288_000978"
     CDS             complement(52447..54165)
                     /gene="proS"
                     /locus_tag="RH288_000978"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDV4030067.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYL
                     VKQIKG"
     gene            complement(54277..54984)
                     /gene="tsaA"
                     /locus_tag="RH288_000979"
     CDS             complement(54277..54984)
                     /gene="tsaA"
                     /locus_tag="RH288_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HDV4030068.1"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     gene            complement(54981..55385)
                     /gene="rcsF"
                     /locus_tag="RH288_000980"
     CDS             complement(54981..55385)
                     /gene="rcsF"
                     /locus_tag="RH288_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HDV4030069.1"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     gene            complement(55503..56318)
                     /gene="metQ"
                     /locus_tag="RH288_000981"
     CDS             complement(55503..56318)
                     /gene="metQ"
                     /locus_tag="RH288_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HDV4030070.1"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(56358..57011)
                     /gene="metI"
                     /locus_tag="RH288_000982"
     CDS             complement(56358..57011)
                     /gene="metI"
                     /locus_tag="RH288_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HDV4030071.1"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     gene            complement(57004..58035)
                     /gene="metN"
                     /locus_tag="RH288_000983"
     CDS             complement(57004..58035)
                     /gene="metN"
                     /locus_tag="RH288_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HDV4030072.1"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEVKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     gene            58223..58798
                     /gene="gmhB"
                     /locus_tag="RH288_000984"
     CDS             58223..58798
                     /gene="gmhB"
                     /locus_tag="RH288_000984"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HDV4030073.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAVAANVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPAQ"
BASE COUNT        13966 a        14641 c        16220 g        14148 t
ORIGIN      
        1 cctctccctc aagggagagg ggaccgatcg agcacaaatt ttgagagata tcttcttctg
       61 tcttgtaaca gaagaacaga aaatcgggct tttgcgcctg aatattgcgg agaaaaagca
      121 tggccgggaa tgaccgcgag ccaattggac gcaaagggaa accgacgcgt ccggtcaaac
      181 aaaaggtaag ccgtcgtcgt tacgaagatg acgatgatta cgacgattat gatgactatg
      241 aggatgaaga accgatgccg cgcaaaggta agggcaaagg caaagggcgt aagcctcgtg
      301 gcaaacgcgg ctggctatgg ctactgctaa aactggctat cgtttttgcc gtgctgatcg
      361 ccatttacgg cgtttatctc gatcaaaaaa ttcgtagccg tattgatggc aaggtctggc
      421 aactgcctgc ggcagtttat ggccgaatgg tcaatcttga gccagacatg accatcagca
      481 agaacgagat ggtgaagctg ctggaggcga cccagtatcg tcaggtgtcg aaaatgaccc
      541 gtcctggcga atttaccgtg caggccaaca gcattgagat gattcgccgt ccgtttgatt
      601 tcccggacag taaagaagga caggtgcgcg cgcgtctgac ctttgatggc gatcatctgg
      661 cgacgatcgt caatatggag aacaaccgtc agttcggttt cttccgtctt gatccgcgtc
      721 tgatcaccat gatctcttcg ccaaacggtg agcagcgtct gtttgtgccg cgcagtggtt
      781 tcccggattt gctggtggat actttgctgg cgacagaaga ccgtcatttt tacgagcatg
      841 atggaatcag tctctactca atcgggcgtg cggtgctggc aaacctgacc gccggacgca
      901 cggtacaggg tgcgagtacg ctgacgcaac agctggtgaa aaacctgttc ctctccagcg
      961 agcgttctta ctggcgtaaa gcgaacgaag cttacatggc gctgatcatg gacgcgcgtt
     1021 acagcaaaga ccgtattctt gagctgtata tgaacgaggt gtatctcggt cagagcggcg
     1081 acaacgaaat ccgcggcttc ccgctggcaa gcttgtatta ctttggtcgc ccggtagaag
     1141 agctaagcct cgaccagcag gcgctgttag tcggtatggt gaaaggggcg tccatctaca
     1201 acccgtggcg taacccaaaa ctggcgctgg agcgacgtaa tctggtgctg cgtctgctgc
     1261 aacagcaaca gattattgat caagaactct atgacatgtt gagtgcccgt ccgctggggg
     1321 ttcagccgcg cggtggggtg atctctcctc agccagcctt tatgcaactg gtgcgtcagg
     1381 agctgcaggc aaaactgggc gataaggtaa aagatctctc cggcgtgaag atcttcacta
     1441 cctttgactc ggtggcccag gacgcggcag aaaaagccgc cgtggaaggc attccggcac
     1501 tgaagaaaca gcgtaagttg agcgatcttg aaactgcgat tgtggtcgtc gaccgcttta
     1561 gtggtgaagt tcgtgcgatg gtcggaggtt ctgagccgca gtttgcgggc tacaaccgtg
     1621 cgatgcaggc gcgtcgttcg attggttccc ttgcaaaacc agcgacttat ctgacggcct
     1681 taagccagcc gaaaatctat cgtctgaata cgtggattgc ggatgcgcca attgcgctgc
     1741 gtcagccgaa tggccaggtc tggtcaccgc agaatgatga ccgtcgttat agcgaaagcg
     1801 gcagagtgat gctggtggat gcgttgaccc gttcgatgaa cgtgccgacg gtaaatctgg
     1861 ggatggcgct ggggctgcct gcggttacgg agacctggat taaactgggc gtaccgaaag
     1921 atcagttgca tccggttccg gcaatgctgc tgggggcgtt gaacttaacg ccaatcgaag
     1981 tggcgcaggc attccagacc atcgccagcg gtggtaaccg tgcaccgctt tctgcgctgc
     2041 gttcggtaat cgcggaagat ggcaaagtgc tgtatcagag cttcccgcag gcggaacgcg
     2101 ctgttccggc gcaggcggcg tatctgacac tatggaccat gcagcaggtg gtacaacgcg
     2161 gtacgggtcg tcagcttggg gcgaaatacc cgaacctgca tctggcaggg aaaacaggga
     2221 ctaccaacaa taacgtagat acctggtttg cgggcattga cggcagcacg gtgaccatca
     2281 cctgggtcgg ccgtgataac aaccagccga ccaaactgta tggtgccagc ggggcaatgt
     2341 cgatttatca gcgttatctg gctaaccaga cgccaacgcc gctgaatctt gttccgccag
     2401 aagatattgc agatatgggc gtggactacg acggcaactt tgtttgcagc ggtggcatgc
     2461 gtatcttgcc ggtctggacc agcgatccgc aatcgctgtg ccagcagagc gagatgcagc
     2521 agcagccgtc aggcaatccg tttgatcagt cttctcagcc gcagcaacag ccgcaacagc
     2581 aacctgctca gcaagagcag aaagacagcg acggtgtagc cggttggatc aaggatatgt
     2641 ttggtagtaa ttaacatcta agcgtgaaat accggatggc gagttgccat ccggtaaaat
     2701 aacatcccat ctaagatatt aaccctttct tttcatctgg ttgtttatta acccttcagg
     2761 aacgctcaga ttgcgtaccg cttgcgaacc cgccagcgtt tcgaatatta tcttatcttt
     2821 ataataatca ttctcgttta cgttatcatt cactttacat cagagatata ccaatggcgc
     2881 gttccaaaac tgctcagcca aaacactcac tgcgtaaaat cgcagttgta gtagccacag
     2941 cggttagcgg catgtctgtt tatgcacagg cagcggttga accgaaagaa gacactatca
     3001 ccgttaccgc tgcacctgcg ccgcaagaaa gcgcatgggg gcctgctgca actattgcgg
     3061 cgcgacagtc tgctaccggc actaaaaccg atacgccgat tcaaaaagtg ccacagtcta
     3121 tttctgttgt gaccgccgaa gagatggcgc tgcatcagcc gaagtcggta aaagaagcgc
     3181 ttagctacac gccgggtgtc tctgttggta cgcgtggcgc atccaacacc tatgaccacc
     3241 tgatcattcg cggctttgcg gcagaaggcc aaagccagaa taactatctg aatggcctga
     3301 agttgcaggg caacttctat aacgatgcgg tcattgaccc gtatatgctg gaacgcgctg
     3361 aaattatgcg tggcccggtt tccgtgcttt acggtaaaag cagtcctggc ggcctgttga
     3421 atatggtcag caagcgtccg accaccgaac cgctgaaaga agttcagttt aaagccggta
     3481 ctgacagcct gttccagact ggttttgact ttagcgattc gttggatgat gacggtgttt
     3541 actcttatcg cctgaccggt cttgcgcgtt ctgccaatgc ccagcagaaa gggtcagaag
     3601 agcagcgtta tgctattgca ccggcgttca cctggcgtcc ggatgataaa accaatttta
     3661 ccttcctttc ttacttccag aacgagccgg aaaccggtta ttacggctgg ttgccgaaag
     3721 agggaaccgt tgagccgctg ccgaacggta agcgtctgcc gacagacttt aatgaagggg
     3781 cgaagaacaa cacctattct cgtaatgaga agatggtcgg ctacagcttc gatcacgaat
     3841 ttaacgacac ctttactgtg cgtcagaacc tgcgctttgc tgaaaacaaa acctcgcaaa
     3901 acagcgttta tggttacggc gtctgctccg atccggcgaa tgcttacagc aaacagtgtg
     3961 cggcattagc gccagcggat aaaggccatt atctggcacg taaatacgtc gttgatgatg
     4021 agaagctgca aaacttctcc gttgataccc agttgcagag caagtttgcc actggcgata
     4081 tcgaccacac cctgctgacc ggtgtcgact ttatgcgtat gcgtaatgac atcaacgcct
     4141 ggtttggtta cgacgactct gtgccactgc tcaatctgta caatccggtg aataccgatt
     4201 tcgacttcaa tgccaaagat ccggcaaact ccggccctta ccgcattctg aataaacaga
     4261 aacaaacggg cgtttatgtt caggatcagg cgcagtggga taaagtgctg gtcaccctag
     4321 gcggtcgtta tgactgggca gatcaagaat ctcttaaccg cgttgccggg acgaccgata
     4381 aacgtgatga caaacagttt acctggcgtg gtggtgttaa ctacctgttt gataatggtg
     4441 taacacctta cttcagctat agcgaatcgt ttgaaccttc ttcgcaagtt gggaaggatg
     4501 gtaatatttt cgcaccgtct aaaggtaagc agtatgaagt cggcgtgaaa tatgtaccgg
     4561 aagatcgtcc gattgtagtt actggtgccg tgtataatct cactaaaacc aacaacctga
     4621 tggcggaccc tgagggttcc ttcttctcgg ttgaaggtgg cgagatccgc gcacgtggcg
     4681 tagaaatcga agcgaaagcg gcgctgtcgg cgagtgttaa cgtagtcggt tcttatactt
     4741 acaccgatgc ggaatacacc accgatacta cctataaagg caatacgcct gcacaggtgc
     4801 caaaacacat ggcttcgttg tgggctgact acaccttctt tgacggtccg ctttcaggtc
     4861 tgacgctggg caccggtggt cgttatactg gctccagtta tggtgatccg gctaactcct
     4921 ttaaagtggg aagttatacg gtcgtggatg cgttagtacg ttatgatctg gcgcgagtcg
     4981 gcatggctgg ctccaacgtg gcgctgcatg ttaacaacct gttcgatcgt gaatacgtcg
     5041 ccagctgctt taacacttat ggctgcttct ggggcgcaga acgtcaggtc gttgcaaccg
     5101 caaccttccg tttctaattt ctcttttggg gcacggattt ccgtgcccat ttcacaagtt
     5161 ggctgttatg caggaataca cgaatcattc cgataccact tttgcactgc gtaatatctc
     5221 ctttcgtgtg cccgggcgca cgcttttgca tccgctgtcg ttaacctttc ctgccgggaa
     5281 agtgaccggt ctgattggtc acaacggttc tggtaaatcc actctgctca aaatgcttgg
     5341 ccgtcatcag ccgccgtcgg aaggggagat tcttcttgat gcccaaccgc tggaaagctg
     5401 gagcagcaaa gcgtttgccc gcaaagtggc ttatttgccg cagcagcttc ctccggcaga
     5461 agggatgacc gtgcgtgaac tggtggcgat tggtcgttac ccgtggcatg gcgcgctggg
     5521 gcgctttggg gcggcagatc gcgaaaaagt cgaggaagct atctcgctgg ttggcttaaa
     5581 accgctggcg catcggctgg tcgatagtct ctctggcggc gaacgtcagc gggcgtggat
     5641 cgccatgctg gtggcgcagg atagccgttg tctgttgctc gacgaaccga cctcggcgct
     5701 ggatatcgcc caccaggttg atgtgctgtc gctggtgcac cgtttaagtc aggagcgtgg
     5761 cctgacggtc attgccgtgt tgcacgatat caatatggcg gcacgctact gtgattatct
     5821 ggtcgccctg cgcggcggtg aaatgattgc tcagggaacg cctgcggaaa ttatgcgcgg
     5881 cgaaaccctc gaaatgattt atggcatccc gatgggtatt ttgccgcatc cggcgggtgc
     5941 tgcacctgtg agttttgttt attgatgagc ggcttacctc ttatttcgcg ccgtcgactg
     6001 ttaacggcga tggcgctttc tccgttgtta tggcagatga ataccgccca cgcggcggct
     6061 attgatccca atcgtattgt ggcgctggag tggttgccgg tggaattact gctggcgctc
     6121 ggcatcgtgc cttacggcgt ggcggatacc atcaactatc gcctgtgggt cagcgaacca
     6181 ccattgccgg actcagtgat cgacgtcggt ttgcgcacag aacctaacct tgaactgctg
     6241 accgaaatga aaccatcgtt tatggtctgg tcggcaggat atggcccttc accagaaatg
     6301 ctggctcgta ttgcgccggg tcgcggattt aacttcagtg acggcaaaca gccgttggcg
     6361 atggcgcgta aatcgctgac ggaaatggca gatttactta acctgcaaag cgcagcggaa
     6421 atgcatttag cgcaatatga agactttatc cgcagcatga aaccccgctt tgtgaagcgt
     6481 ggtgcgcgtc cgttattgct gacgacgctt atcgatccgc gccatatgct ggtcttcggt
     6541 ccaaacagct tgttccagga aattcttgat gagtacggca tcccaaatgc ctggcaaggg
     6601 gaaaccaact tctggggcag taccgccgtc agtatcgatc gtctggcggc gtataaagac
     6661 gttgatgtgc tctgttttga tcacgacaac agcaaagaca tggatgcgct aatggcaacg
     6721 ccgctgtggc aggccatgcc gtttgtccgc gccggacgct ttcagcgcgt acctgcagtc
     6781 tggttttatg gtgcgacgct ctcggcaatg cactttgtgc gcgttctgga taacgccatc
     6841 ggaggtaaag cgtgagtaaa cgaattgcgc ttttcccggc gttattgctg gcgctgttag
     6901 tgattgtcgc tacggcgctc acctggatga acttctcgca ggcgctgccg cgtagccagt
     6961 gggcgcaggc tgcctggtcg ccggatattg acgtcatcga gcagatgatt tttcactaca
     7021 gcttgttgcc gcgtctggcg atttcgctgc tggtgggcgc gggtctgggg ctggtgggcg
     7081 tgctgtttca gcaagtgctg cgtaacccgc tggcggagcc gacgacgctt ggcgttgcta
     7141 caggcgcgca actggggatt accgtcacta cgctctgggc gatccctggt gcgatggcga
     7201 gccagtttgc tgcgctggca ggggcttgtg ttgttggctt aattgtcttt ggcgtcgcgt
     7261 gggggaaacg gctgtcgccg gtaacgctga ttctcgcggg gttggtagtg agcctttatt
     7321 gcggcgcaat caatcagtta ctggttatct tccatcatga ccaactgcaa agcatgtttc
     7381 tgtggagcac tggaacgctg acgcaaaccg actggggcgg cgttgagcgt ttatggccgc
     7441 agctgctggg cggtgtgatg ctgacgttgc tgctacttcg tccgttaacc ctgatggggc
     7501 ttgatgatgg cgtggcgcgc aatctcgggc tggccttgtc gcttgcgcgt ctggcggcgc
     7561 tgtcgctggc gattgtcatc agtgcgctgc tggtgaacgc tgtggggatt atcggcttta
     7621 tcgggttgtt cgcgccgctg ctggcaaaaa tgctgggggc gcggcgtctg ctgccacgac
     7681 tgatgctggc gtcgttgatt ggtgcgctga tcctctggct ttccgatcaa atcatcctct
     7741 ggctgactcg cgtgtggatg gaagtgtcca ccggttcggt cactgcgttg atcggtgcgc
     7801 cgctgctact gtggctgttg ccgcgtttac gcagcattag cgcgccggat atgaaggtca
     7861 acgatcgtgt cgcggctgaa cgccaacatg tgctggcgtt tgccctcgcg ggcggcgtgc
     7921 tgctgttgat ggctgtggtg gtggcgctgt cgtttggtcg tgatgcgcac ggctggacgt
     7981 gggcgagcgg ggcgttgctc gaggatttaa tgccctggcg ctggccgcga attatggcgg
     8041 cgctgtttgc gggcgtcatg ctggcggtgg cgggctgtat tattcagcga ctgaccggaa
     8101 acccgatggc aagcccggaa gtgctgggga ttagctccgg cgcggcgttt ggcgtggtgt
     8161 tgatgctgtt tctggtgccg ggtaatgcct ttggctggct gttacctgca ggcagtctcg
     8221 gcgcggcggt gacgctgttg atcattatga tcgccgccgg ccgcggtgga ttttccccac
     8281 accgtatgtt actggcgggg atggcgttaa gcaccgcgtt caccatgctt ttgatgatgt
     8341 tgcaggcaag tggtgacccg cgaatggcgc aagtgctgac ctggatttcc ggttcgacct
     8401 acaacgcgac cgatgcgcag gtctggcgca ccggaattgt gatggtgatt ttgctggcga
     8461 ttaccccgct gtgccgccgc tggctgacca ttttaccgct gggtggtgat accgcccgag
     8521 ccgtaggaat ggcgctgacg ccgacgcgaa ttgcgctgct gctgttagcg gcttgcctga
     8581 cggcgaccgc gacgatgact attggaccgt tgagttttgt tggtttaatg gcaccgcata
     8641 ttgcgcggat gatgggcttt cgacggacga tgccacacat cgtaatttcg gcgctggtgg
     8701 gtggtttact gctggtgttc gctgactggt gtgggcggat ggtgctgttt ccattccaga
     8761 tcccggcggg gctgctgtca acctttatcg gcgcgccata ttttatctat ttgttgagaa
     8821 agcagagccg ttaatttttc catataacgg ccctgtacgc ctggacggat aaagcgttta
     8881 cgcgacaacg gatgcccgat gcgacgctgg cgcgtcttat cgggcctaca aacggccccg
     8941 aatcgtaggt cggataaggc gttcacgccg catccgacaa accatgctgg atcacaactt
     9001 cgcaaacacc cgacgtgcag catcgatggt gttattgata tcttccatgc tgtgcgccac
     9061 ggacataaag cccgcttcaa acgctgacgg tgccaggtaa acaccttcgt ccagcatcat
     9121 atggaagaaa cgcttaaagc gttccacgtc acaggccatc acatcctgat agcacgtcac
     9181 ggactcggcg tcggtaaaga aaataccgaa catgccgcca acgtggttaa cgaccagcgg
     9241 aattccggct tcttctgccg cttccagcag accttctgcc agacgtgttg tcagctcatc
     9301 cagcgtttcg tgaacgcccg gctgcgcgac ttcattcaga caggcgaaac ccgctgccat
     9361 cgcaatcggg ttaccggaaa gcgtacccgc ctgatagacc ggacccgtcg gggccagcgc
     9421 atccattaca tcacgacgac caccgaatgc gcctaccggc attccaccgc cgatgatttt
     9481 gccgaggcag gttaaatctg gcactacgcc gtaataatcc tgtgcgccag ctagcgctac
     9541 gcggaaaccg gtcatcactt catcgatgat cagcaacgcg ccaaattcgt cgcacagcgc
     9601 gcgcagacct ggcaggaact ctggcagcgg cggaacacag ttcatattgc ctgccaccgg
     9661 ctcgacgata atacaggcaa tctcttgcgg gtattgctca aatgcggcgc gtacagaagc
     9721 cagatcatta taagtacagg ttaaggtatg tttggcgaaa tctgccggaa cgcccggcga
     9781 gtttggctgg cctaacgtga gtgcgccaga accggctttc accagcaggc agtcagcgtg
     9841 accatggtaa cacccttcaa atttaataat tttgtcgcga ccggtaaaac cacgggccag
     9901 gcggatggcg ctcatggtcg cttcagtgcc ggagttcacc atgcgcacca tatccatggt
     9961 cgggaccagt tcggtcacca gttgcgccat tttcacttcc atttcggttg gtgcaccaaa
    10021 gcttaaacca cgctcggcgg cttcaatcac ggcattgcgg attgccggat ggttatggcc
    10081 cagcaccatc ggcccccagg aaccgacata atcgatatag gctttgccat caacatcgta
    10141 cagataagcg ccgtccgctt tttcgataaa cagtggagtg ccgcccacgc cagtaaaggc
    10201 gcgaacaggg gagttcacac cgccagggat cagctcgcgc gctgcgctgt aaagattttc
    10261 agacttactc atggagggtt cctgattcgt agaaaaagtg aatggctgct attctatgtt
    10321 attcataaca agttaaatac tcgtcaaaca tcaggctgct tgtactggtg caatcctgat
    10381 ttcttagagt ataaaagttt tgtgcatttg aaacattacg ctttgcaaag gattttcatg
    10441 gaacgtgcga gtaaaatgcc gtcatcttat ttgtatgacc aataagtgat cattggatga
    10501 aaactgatac tccctcttta gaaacaccgc aggccgcgcg cctgcgacgc agacaactga
    10561 ttcgccaact tcttgagcgc gataaaaccc cgttagccat tttgtttatg gcggcagtcg
    10621 tcggcacgct tgttgggctg gcagcggttg cttttgacaa aggtgtcgcc tggttgcaga
    10681 accaacgtat gggggcgctg gtacatactg ctgataatta tccgcttctg ttaaccgtcg
    10741 cttttctctg ttcggcggtg ctggcgatgt ttggctactt tttggtgcgc aaatacgcgc
    10801 cggaagcagg tggttcgggg atcccggaaa ttgaaggggc gctggaagat caacgtcccg
    10861 ttcgctggtg gcgtgtattg ccggtgaagt tctttggcgg gctggggaca ctcggcggag
    10921 gcatggtgtt ggggcgcgaa gggccaaccg tgcagatcgg cggtaacatt ggccgtatgg
    10981 tgcttgatat tttccgcctg aaaggtgacg aagctcgcca tacgctgctg gcaaccggtg
    11041 ctgctgcggg gctggctgcg gcctttaacg cgccgctggc gggtattttg tttattatcg
    11101 aagagatgcg tccgcagttt cgctatacgt taatttcgat taaagcggta tttattggtg
    11161 tcattatgtc gaccattatg taccggattt ttaatcatga agttgcgttg attgacgtcg
    11221 gtaaactttc tgatgcgccg cttaatacgc tgtggcttta tctgatcctc ggtattattt
    11281 ttggcatttt cggccctatt tttaataaat gggtgctggg gatgcaggat ttgctgcacc
    11341 gtgtgcacgg cggcaatatt accaaatggg tgctaatggg cggtgcgatt ggcggtctgt
    11401 gtggattgct ggggtttgtg gcaccagcaa cgtcgggcgg cggttttaac ctgattccta
    11461 tcgctaccgc ggggaatttc agcatgggaa tgctggtgtt tatcttcgtc gcgcgggtca
    11521 ttaccacctt actctgcttc tcttccggcg cgccgggcgg tatttttgcc ccgatgctgg
    11581 cgctgggtac tgtgctggga accgctttcg gaatggttgc cgttgagctg tttccgcaat
    11641 atcaccttga ggcggggacg tttgctattg ccggaatggg ggcattactg gcggcatcta
    11701 ttcgcgcgcc gttaacgggg atcattctgg ttctggagat gaccgataac taccagctca
    11761 ttttgccaat gattattacc ggtcttggcg caacactatt agcgcaattt accggcggga
    11821 aaccgctata ctcggcgatt cttgcgcgca cgctggcaaa acaggaagct gagcaactgg
    11881 cgcgaagcaa ggccgcatca gccagcgaga atacttgaac gaaataccag ggtattagat
    11941 aatggcgatt attattgggt tagaatttgc ccaattgccg atgtcgtttg gagcaaaata
    12001 tgagtgatga cgtagcactg ccgctggagt ttaccgacgc agcagccaac aaagttaaaa
    12061 gcctgatcgc tgacgaagat aacccgaatc tgaaattacg cgtgtatatc accggtggcg
    12121 gttgcagcgg cttccagtat ggtttcacct ttgatgatca ggtgaacgaa ggcgatatga
    12181 ccatcgaaaa acagggcgtt ggcctggtgg ttgatccgat gagcctgcaa tatctggtcg
    12241 gcggttccgt tgattatacc gaaggtctgg aaggttctcg tttcatcgtg accaacccga
    12301 acgcgaaaag cacctgcggt tgcggttctt cctttagtat ctaatctgtt gttcatgtgc
    12361 cggataaact atccggcaca tcttctctct tcaacgccca ttctcatcca gcgcaaacgt
    12421 cggtagctta agatgccaac gaatagccgc cagccgaatc aatagcgtca cgaccatgcc
    12481 catcatactg gctgtttcca gtggtacgga aaatgtgtaa taagccgtag cgtggacaat
    12541 accgccgata atacaggcag ttgcgtagat ttctgtacgt aaaatcatgg ggatttcgcg
    12601 ggccagaaca tcacgaatga tcccgccgcc aacgccagta atgacgccca tacaaaccgc
    12661 gattaacgga ccggcttccg cattaaaggc tttattcacg ccaatgccga caaacaccgc
    12721 cagaccaacg gcgtccagca ccggcaacat ccattttggt aagcgtcttg gctggcgcac
    12781 cagcacgatg gtcagcatgc tggtgaccat tgcaacgacc agatcggtgg gatctttcac
    12841 ccaaaatacc gggccgtgat ccagcgccat gtcgcgaatt gtcccgccgc ctactgcggt
    12901 taccacgccc agtaccagaa caccaaaagg gtccatacgc aattttccgg ctaacaaaac
    12961 gccggagatg gcaaataccg ctgtgccgac tatatccagc caatagacga gcattgttca
    13021 atccccactg agcacctgaa aaggtcaggc gctaatctac ctgtgaaagc gcattacaga
    13081 gctgttgtgc agcgaggata atacgtgggc ttgcacgttc aaaccagtca ctcgtgagag
    13141 gaataacggg aattttgagc tgttcacccc agtattgttt gattttagga atttggtccg
    13201 gtccgcctgt aatgacaatc gcctgtggcg agcgtgctaa cacctgttcg cggctaactt
    13261 gcggccaggg aacccggctg tctttaaaga tgttttctcc gccacaaact tcgagtacct
    13321 ggttctgaat cgactctttt ccactggtaa atggcggatt aatgccgaat tgcagaaaaa
    13381 cacgtttttt aggtttatca gcatattgcg ctttcaattg cgcgtactga tccagcaggg
    13441 attgcgcggc ttgttcggcc ttgtctggtt gcggactcca gggggccagt tgacgtaacg
    13501 cattggcaat ttgttcaatg cttgtcgcat cgacccacat cacttttatt cccagcgaag
    13561 ccagctggtc aacctgccgc tcggcattac ctccacgcca ggcaatcacc agatcgggtt
    13621 tcagcgcgac aatgcgttcc agattcatcc cctgccaggt ggaaacctgc tcaatctttt
    13681 gcgcttgtgg aggatagtcg gaatagctgc tgaccccaac cggcgtgatc ccggcggcaa
    13741 aggcaagttc agtgttggcg ggagaaagcg tgatgacgcg cggcgcggcg ttgagccaca
    13801 gtggcgcaag aaaagacagg gcgaccagcg ccctgaacag tgacttagcc atgtgcaagt
    13861 ttctgcacca gtgactcaac catcaggctg gactgtttag cggcaacagc caggaactca
    13921 tcgaagctaa gatgagactg ttgatcggcc acgtcggaga tggcgcgtac gacaacaaac
    13981 gggacgttga aattgtggca gacatgggcg attgccgtcg cttccatctc tacagcaatg
    14041 gcctgtggga agttgtggcg gattttcgcc agaccaacag aaccgttgat gaaagcgtcg
    14101 ccgctaacaa tcaggccacg tacagcgtta agattcagtt cggcaatgca ggcctcagcg
    14161 gcagcgatca gtttatcgtc agctttaaag cctgccggac agcctggtaa ctgaccgtat
    14221 tcataaccaa atgccgtgac atccgcgtcg tgataacgtg cttcgtccga gacaacgata
    14281 tcgcccactt tcaacgttgg tgccaggcca ccggcagaac cggtgttaat aatcacatct
    14341 ggcttgcagt gttccaacag caaagtggca cccagcgccg cagcgacttt accgatgccc
    14401 gatttcagaa gcgcaacctc ggttccattc agttggccgg tatagatttc gcaaccgccg
    14461 agactgatag tttgacggtt ttcgattttg tcacgcagca gcgtaacttc ttcttccatt
    14521 gcaccaatga tgccgatttt catagattta ctcgcgataa gcccgatttg aaggcatagt
    14581 ttaccatgcg cttacgggga agcgtatttc tcacgcggga gaggacatgg cacagattga
    14641 tttccgaaaa aaaataaact ggcatcgtcg ttaccgttca ccgcagggcg ttaaaaccga
    14701 acatgagatc ctgcggatct tcgagagcga tcgcgggcgt atcatcaact ctccggcaat
    14761 tcgtcgtctg caacaaaaga cccaggtttt tccactggag cgcaatgccg ccgtgcgcac
    14821 gcgtcttacc cactcgatgg aagtccagca ggtggggcgc tacatcgcca aagaaatttt
    14881 aagccgtctg aaagagctta aattactgga agcatacggc ctggatgaac tgaccggtcc
    14941 ctttgaaagc attgttgaga tgtcatgcct gatgcacgat atcggcaatc cgccgtttgg
    15001 tcattttggc gaagcggcga taaatgactg gtttcgccaa cgtttgcacc cggaagatgc
    15061 cgaaagccag cctctgactg acgatcgctg cagcgtggcg gcactacgtt tacgggacgg
    15121 ggaagaaccg cttaacgagc tgcggcgcaa gattcgtcag gacttatgtc attttgaggg
    15181 gaatgcacaa ggcattcgcc tggtgcatac attgatgcgg atgaatctca cctgggcaca
    15241 ggttggcggt attttaaaat atacccgtcc ggcgtggtgg cgtggcgaaa cgcctgagac
    15301 acatcactat ttaatgaaaa agccgggtta ttatctttct gaagaagcct atattgcccg
    15361 gttgcgtaaa gaacttaatt tggcgcttta cagtcgtttt ccattaacgt ggattatgga
    15421 agctgccgac gacatctcct attgtgtggc agaccttgaa gatgcggtag agaaaagaat
    15481 atttaccgtt gagcagcttt atcatcattt gcacgaagcg tggggccagc atgagaaagg
    15541 ttcgctcttt tcgctggtgg ttgaaaatgc ctgggaaaaa tcacgctcaa atagtttaag
    15601 ccgcagtacg gaagatcagt tttttatgta tttacgggta aacaccctaa ataaactggt
    15661 accctacgcg gcacaacgat ttattgataa tctgcctgcg attttcgccg gaacgtttaa
    15721 tcatgcatta ttggaagatg ccagcgaatg cagcgatctt cttaagctat ataaaaatgt
    15781 cgctgtaaaa catgtgttta gccatccaga tgtcgagcag cttgaattgc agggctatcg
    15841 ggtcattagc ggattattag agatttatcg tcctttatta agcctgtcgt tatcagactt
    15901 tactgaactg gtagaaaaag aacgggtgaa acgtttccct attgaatcgc gcttattcca
    15961 caaactctcg acgcgccatc ggctggccta tgtcgaggct gtcagtaaat taccgtcaga
    16021 ttctcctgag tttccgctat gggaatatta ttaccgttgc cgcctgctgc aggattatat
    16081 cagcggtatg accgacctct atgcgtggga tgaataccga cgtctgatgg ccgtagaaca
    16141 ataaccaggc ttttgtaaag acgaacaata aatttttacc ttttgcagaa actttagttc
    16201 ggaacttcag gctataaaac gaatctgaag aacacagcaa ttttgcgtta tctgttaatc
    16261 gagactgaaa tacatgaaaa aaaccacatt agcactgagt gcactggctc tgagtttagg
    16321 tttggcgtta tctccgctct ctgcaacggc ggctgagact tcttcagcaa cgacagccca
    16381 gcagatgcca agccttgcac cgatgctcga aaaggtgatg ccttcagtgg tcagcattaa
    16441 cgtagaaggt agcacaaccg ttaatacgcc gcgtatgccg cgtaatttcc agcagttctt
    16501 cggtgatgat tctccgttct gccaggaagg ttctccgttc cagagctctc cgttctgcca
    16561 gggtggccag ggcggtaatg gtggcggcca gcaacagaaa ttcatggcgc tgggttccgg
    16621 cgtcatcatt gatgccgata aaggctatgt cgtcaccaac aaccacgttg ttgataacgc
    16681 gacggtcatt aaagttcaac tgagcgatgg ccgtaagttc gacgcgaaga tggttggcaa
    16741 agatccgcgc tctgatatcg cgctgatcca aatccagaac ccgaaaaacc tgaccgcaat
    16801 taagatggcg gattctgatg cactgcgcgt gggtgattac accgtagcga ttggtaaccc
    16861 gtttggtctg ggcgagacgg taacttccgg gattgtctct gcgctggggc gtagcggcct
    16921 gaatgccgaa aactacgaaa acttcatcca gaccgatgca gcgatcaacc gtggtaactc
    16981 cggtggtgcg ctggttaacc tgaacggcga actgatcggt atcaacaccg cgatcctcgc
    17041 accggacggc ggcaacatcg gtatcggttt tgctatcccg agtaacatgg tgaaaaacct
    17101 gacctcgcag atggtggaat acggccaggt gaaacgcggt gagctgggta ttatggggac
    17161 tgagctgaac tccgaactgg cgaaagcgat gaaagttgac gcccagcgcg gtgctttcgt
    17221 aagccaggtt ctgcctaatt cctccgctgc aaaagcgggc attaaagcgg gtgatgtgat
    17281 cacctcactg aacggtaagc cgatcagcag ctttgccgca ctgcgtgctc aggtgggtac
    17341 tatgccggta ggcagcaaac tgaccctggg cttactgcgc gacggtaagc aggttaacgt
    17401 gaacctggaa ctgcagcaga gcagccagaa tcaggttgat tccagctcca tcttcaacgg
    17461 cattgaaggc gctgagatga gcaacaaagg caaagatcag ggcgtggtag tgaacaacgt
    17521 gaaaacgggc actccggctg cgcagatcgg cctgaagaaa ggtgatgtga ttattggcgc
    17581 gaaccagcag gcagtgaaaa acatcgctga actgcgtaaa gttctcgaca gcaaaccgtc
    17641 tgtgctggca ctcaacattc agcgcggcga cagcaccatc tacctgttaa tgcagtaatc
    17701 tccctcaacc ccttcctgaa aacgggaagg ggttctcctt acaatctgtg aacttcacca
    17761 caactccata catcttcatc atcctttagg catttgcaca atgccgtacg ttacgtactt
    17821 ccttatgcta agccgtgcat aacggaggac ttatggctgg ctggcatctt gataccaaaa
    17881 tggcgcagga tatcgtggca cgtaccatgc gcatcatcga taccaatatc aacgtaatgg
    17941 atgcccgtgg gcgaattatc ggcagcggcg atcgtgagcg tattggtgaa ttgcacgaag
    18001 gtgcattgct ggtactttca cagggacgag tcgtcgatat cgatgacgcg gtagcacgtc
    18061 atctgcacgg tgtgcggcag gggattaatc taccgttacg gctggaaggt gaaattgtcg
    18121 gcgtaattgg cctgacaggt gaaccagaga atctgcgtaa atatggcgaa ctggtctgca
    18181 tgacggctga aatgatgctg gaacagtcgc ggttgatgca cttgttggcg caggatagcc
    18241 gtttgcggga agaactggtg atgaacctga ttcaggcaga ggagaatact cccgcactta
    18301 ctgaatgggc gcaacggctg gggatcgatc tcaatcaacc gcgagtggtg gctattgttg
    18361 aggtcgacag cggtcagctt ggcgtggaca gcgcaatggc ggagttacaa caactgcaaa
    18421 acgcgctgac tacgcccgag cgtaataatc tggtggcgat tgtctcgcta accgaaatgg
    18481 tggtgttgaa accggcgttg aactcttttg ggcgctggga tgcagaagat catcgtaagc
    18541 gagttgaaca actgattacc cgcatgaaag agtacggcca gctgcgtttt cgcgtttcac
    18601 tgggcaacta ttttaccggt cctggcagta ttgcccgatc ctatcgtacg gcgaaaacga
    18661 cgatggtggt gggtaaacag cggatgccag aaagtcgctg ctatttttat caggatctga
    18721 tgttacctgt gttactcgac agtttgcgtg gcgactggca ggccaacgaa ctggcgcgac
    18781 cgctggcgcg gctgaaaacg atggacaata acggcttgct gcgacgaacg ctggcggcgt
    18841 ggtttcgcca caatgtgcaa ccgctggcaa cgtcaaaggc gttgtttatt catcgtaata
    18901 ccctggagta tcggcttaat cgtatatcgg aactgaccgg gcttgatttg ggcaattttg
    18961 atgacaggtt gctgctgtat gtggcgttac aactggatga agagcggtag gttatgcgtt
    19021 aaggttgagg cggcgctggc tcattcccct cagcccgaag ggtagagggg aatgcccgaa
    19081 ttaaccgtca gttcgggatt atttacgcgt tagtttttcc agatcggctt caatctcgct
    19141 gatcttattg gttacgactg actccaggtg acgtaagtcg tcgaggatct tacgcttaag
    19201 atcaacttcg ctgcggtcac gctggcagat ttgatcaagc tcatcaatga tataccgtag
    19261 attcgggctg atttcctgga cttctttata accctgaccc acaccatcag cgacgaccgt
    19321 tttacgctga cgcggatatt taaacttaac gctcttggcg aaaaactcgc ctttgtcttt
    19381 ctggaaatag attttcagaa tatcgttgtt ggcttcctgc cggaggctgt aacgatcaat
    19441 ttcttcagga ttggtaatac ccagactttt cagattgtcg tacatagcgt tacctcaaaa
    19501 tgagtcagta aattgtgctt attttagcat ttggcctggc ccgcccggct cgactgtgat
    19561 cgcagaaagc ctttttcttc cagacttcta tcatggcgta aaaatcaaaa aattacctgc
    19621 tttattctgg tgataaaatt cacgatctac accagttcca gcatcgttac ttccgggcgg
    19681 cagttcagac gcaaaccata caaactgccc acgccacggg ttgtgtagat gtgtctttcg
    19741 ccaaaggcat ttaatccggc gacgtaacgt ttatcttcga caggggcaaa aggttcacca
    19801 accaacggta cgcgcagttg cccgccgtga gtatggccgc acagcatcag atcccagggt
    19861 tcatcacgca tgacttcttt gctgtcggga ttatgcgcca gcaccagtct tggcagattg
    19921 gcttcgctgg cgggaggcgg tttgcattgt ccggcccata agtcaccagt gcctaccagt
    19981 tcgaattgcc tgttcggcgt ggcgatcacc gtagcctggt taaacaacac cgtgatgccc
    20041 gctgatttca acgtctcgcc aattaagtga tttttttctg taccaacagg gcgatcgtgg
    20101 ttgccgaagc aggcaaacgt cggcgcacat tcggcaaggg gggagagtac gtcactaaac
    20161 gccgaaaaat tcagcgacat atcaaataat acgtaatcgc cgcccagtaa tatcaaatcg
    20221 ggcttttgtt ctatgccaag agcaatcgcg tcagaaatca ggcttaaagg aacaaaacga
    20281 gagtaatgga gatcggccag aaaaagaatt ttgaatggtg ctgcgttgtc tttaaaaaag
    20341 gcgaggcggt gacggattaa ttcaaaccag cctggctcac agtaatgcat ataaccgaaa
    20401 cctgagctcg tggctatcgt cgcggcagta gcctgcaaaa atcggcggcg tgaaatcatc
    20461 gctcatccct gcaaaaaaat cgggcagcgt cgtgctgccc gtgtgcatac ttttagtcga
    20521 tggtacgcag cagttcgtta atgccgactt tgccgcgagt tttcgcgtca actttcttaa
    20581 cgataaccgc acagtagagg ctgtatttgc catcttttga cggcagatta cctgaaacaa
    20641 ccacagaccc cgccggaacg cgaccgtagt ggatttcgcc ggtttcacgg tcgtaaatac
    20701 gggtgctctg accaatgtat acgcccatgg aaatgacgga accttcttcg acaatcaccc
    20761 cttcaaccac ttcagagcgc gcgccgatga agcaattatc ttcaatgatg gttgggttag
    20821 cctgcagcgg ttccagcacg ccgccgatgc ccacgccacc ggaaaggtgg acgtttttac
    20881 caatctgcgc acaagaaccg acggtcgccc aggtatcaac catggtgcct tcatcaacat
    20941 atgcgccgat gttgacgtaa gacggcatca gcacggtgtt acgggcaata aacgcaccct
    21001 gacgtaccgc cgctggtggc acaacgcgga agccttcttt ctggaaacgt gcttcgtcgt
    21061 agtcggcgaa tttcatcggc actttgtcga agtagcggct ttctgcccct tcgatcacct
    21121 gattatcatt aatacggaaa gagagcagca ccgctttttt caaccactga tgcgtcaccc
    21181 actgaccgtc aattttttcc gctacacgca gtgcgccgga atccagcagg gcgatcacct
    21241 gatttaccgc ttcgcgggta acggtgtctg cattggctgg cgtgatctcg gcacggcgtt
    21301 caaaagcggt ttcaataatg ttctgtaact gctgcattgt taaactcttt tcatatcagt
    21361 aaacacatca ccctttatcg tttggattga gggcctctgt caaccgctga tgcacttcct
    21421 gctgcaactc gttattaagc gcacgccggt cagcggtggc aattatgaat aaatcttcta
    21481 ctcgctcgcc aatggttgta attcgggcac catgaagcga aattcccaga tcggcaaaaa
    21541 ttttcccgac tcgcgccagc agtccaggtt ggtcgagggc gatcagttcg aggaacgatt
    21601 tgcggtcggt atgggtcggc aaaaacgtta cttcggtttc aacagtaaaa tggcgtaatt
    21661 tggcgggttg gcgacggggc tgcggtggct gccagctact ttgcgtcagt acttgctcca
    21721 gaccaaaccg aataacctca tgacgatctg cggacagcgg gttgccatcg ggttccagca
    21781 cgataaaggt atccatcgcc ataccgtcgc gagtggtgaa aatttgtgcg tcgtgaacac
    21841 ttaaattgcg gcggtctaat tcggcacaga cggcggcaaa cagataaggg cggtccgggc
    21901 tccagataaa aatctcggtg cctccacgcg tagcctgcgg gctaagcaat accagcggtt
    21961 tgcttaaatc atgctgtaat aaatggcggg catgccaggc cagttgattt gggctatggc
    22021 ggacaaaata gttagcacga cagcgtgacc aaatttggtg cagcgcctct tcgtcgatgt
    22081 tatccatgcg cagtagtgcc agtgcctgga gttggtgatg gcgaacccgt tcgcgcatat
    22141 ccggcgtgtt ttgcattccg cgtcgtagct gcttttcggt ggcaaagtag agctcacgca
    22201 acagactttg cttccagcta ttccacagcg tttcgttggt ggcgcaaatg tcagccacag
    22261 tcaggcatac cagatagcgc agacgatttt ccgtttgcac ttcttcggca aactgcttga
    22321 tgacttccgg gtcctgaata tcgcggcgtt gggcggtcac cgacatcaac aggtgctggc
    22381 gaaccagcca ggcgaccagc tgtgtttcgc gtgagttcag cccgtggagt tcggcaaaat
    22441 gcactacatc ctgagcaccg agaatggagt ggtcgccgcc gcgtcctttg gcgatatcgt
    22501 gaaacagcgc ggcgatgaaa atcagctcag ttgacggcag gcgcggccag acgtccacac
    22561 acaacggatg gcgctggcgc gtttcttcac tggcaaaact ctccagtttc agcatcacgc
    22621 ggatagtatg ttcatccacc gtgtaggcgt ggaacagatc aaactgcatc tgcccgacga
    22681 tatgcgacca ttgcggcata tacgcgccga gcacgctatg gcgatgcatt ggcaatagcc
    22741 cgcgccgcac cgctccgggg tgacgcagaa tgctcaaaaa cagttttcgt gcttccggaa
    22801 tattacacag cggttgttgc agatggcgac gggcatggcg taactggcgc agcgtggtgg
    22861 agtaaatgcc ggtgatcgca ctgttgtgca ccatggtgta gaacatacgc aagatggctt
    22921 ccggctggcg cataaatagt gtttcatcac gcaggtcgat tagcgtaccg cgtagctgaa
    22981 actcatcgtc gattggacgt ggtttttcgt cggcgggaag ggcgaggatg gcttcatcga
    23041 acagttgcag cagcatctgg ttgagttcac tgacgcggcg tgtaacgcgg aagtaatcct
    23101 tcatcatccg ctcgaccggt tcgttacctt caccactgta attcagacgc tgggcgacgc
    23161 taagctggcg atcgaataac aggcgattat cgtaacggct gacgaccaga tgcagggcaa
    23221 agcgaatacg ccacaatata tgcagacatt cgtttaattc cgcccgctcc gctgaggtta
    23281 agaagccaaa cccgaccatt tcatccagcg atgttgcgcc aaaatgacgg cgggccaccc
    23341 attgcagagt gtggatatcg cgcaagccgc cagggctgct tttgatgtct ggttcaaggt
    23401 tgtagctggt gccatggtaa cgctgatggc gctggttctg ttcttcaact ttcgccgcgt
    23461 agaacttgtc ggaaggccag aatccttcgc tgaaaatatg tttttgcagt tcgaggaaca
    23521 gcgcaacatc gccaattaat aagcgggatt cgattaaatt ggtggcgacg gttaaatccg
    23581 ataacccttc cagcatgcac tcttcaagcg tgcgcacgct atgaccgact tccagcttta
    23641 catcccagag cagcgttaac agctcgccca ctttttgcgc ctgatcgtcc gggagctttt
    23701 tacggcttaa aatcagtaaa tcgacgtctg aaagtggatg cagctcgcca cgaccgtagc
    23761 caccgacggc gaccaatgcc aggtcggcaa tctggctgaa tcccgcttca atccataatc
    23821 gttgcaggag ctggtcgata aactcggtgc gcgcctcaat caactgttct gcagagatcc
    23881 cattgtcaaa ggcatcaccc agccaacgct ggaaagtatc gatatgggct tttatcccac
    23941 cgacggttaa ttcatcacgg ggccagacgc atggattttg cggttgaccg ggcagggtgg
    24001 ggagagcggt gtttgcgtac tgttctggaa gggtattcat tgtgcgccac ccataagatt
    24061 aaattatcgc attaaaaaag ccggcattcg ccggcttcat cttattcgtc gtgcgagatt
    24121 atcgccggga tggtgtcatc cttgcgtagc gtcagaattt cgcagccgtt atcagtcacc
    24181 acaatagtat gctcatattg tgcagacaag ctgcgatctt tggtttttac cgtccagcca
    24241 tctttcatgg tgcggatctc ttttttaccc gcgttgacca ttggctcgat ggtgaacgtc
    24301 atcccaggtt tcagtacgac gttggtttca cgggagtcat agtgcagcac ctgcggttct
    24361 tcatggaagc cgcgaccaat accgtgtccg caatattcac gaacgacgga gaagccttct
    24421 gcttcgacaa atttctgaat cgccgcaccg atttcgcgca gattaatgcc tggttttacc
    24481 atgcgtagcg ccaggtacag gctttcttgc gtgatgcggc acagacgttc gcccatgatg
    24541 gtcggcttac cgacgataaa cattttcgag gtatcgccgt ggaaaccatc tttgattacg
    24601 gtgacatcaa tgttaacgat atcgccatct ttcagcagct tagcatcgtc cgggataccg
    24661 tggcacacca cttcattaat agagatgcaa acggatttcg gatagccgtg atagccgagg
    24721 caggcagaaa ccgcgtgttg ttcattaaca atgtaatcat tacagatgcg atccagctcg
    24781 ccggtgctga cgcccggttt aacatacggt tcgatcatct ccagcacttc ggcagccagt
    24841 cggccagcga cgcgcatttt ttcgatatct tctggggtct tgattgagat agccattaat
    24901 tctgtccatc agcgtcggtg ataccgacaa tatatatgta agtgccgtca atggtatcac
    24961 acccgggcaa attgagaatc attctgaatt tcgccaaacg tgccactgaa ggttttctat
    25021 aatagaaaat tcgacgtctg atgctgtaca cagcgccaac aattattggt gtccacgacg
    25081 tatttgtggt ataaagcgcg ccggacttcc gatccatttc gtatacacag actggacgga
    25141 agcgacaatc tcactttgtg taacaacaca cacgtatcgg cacatattcc ggggtgccct
    25201 ttggggtcgg taatatggga tacgtggagg cataacccca acttttatat agaggtttta
    25261 atcatggcaa ctgtttccat gcgcgacatg ctcaaggctg gtgttcactt cggtcaccag
    25321 acccgttact ggaacccgaa aatgaagccg ttcatcttcg gtgcgcgtaa caaagttcac
    25381 atcatcaacc ttgagaaaac tgtaccgatg ttcaacgaag ctctggctga actgaacaag
    25441 attgcttctc gcaaaggtaa aatccttttc gttggtacta aacgcgctgc aagcgaagcg
    25501 gtgaaagacg ctgctctgag ctgcgaccag ttcttcgtga accatcgctg gctgggcggt
    25561 atgctgacta actggaaaac cgttcgtcag tccatcaaac gtctgaaaga cctggaaact
    25621 cagtctcagg acggtacttt cgacaagctg accaagaaag aagcgctgat gcgcactcgt
    25681 gagctggaga aactggaaaa cagcctgggc ggtatcaaag acatgggcgg tctgccggac
    25741 gctctgtttg taatcgatgc tgaccacgaa cacattgcta tcaaagaagc aaacaacctg
    25801 ggtattccgg tatttgctat cgttgatacc aactctgatc cggacggtgt tgacttcgtt
    25861 atcccgggta acgacgacgc aatccgtgct gtgaccctgt acctgggcgc tgttgctgca
    25921 accgtacgtg aaggccgttc tcaggatctg gcttcccagg cggaagaaag cttcgtagaa
    25981 gctgagtaat aaggcttgat aactccccca aaatagttcg agttgcagaa aggcggcaag
    26041 ctcgagaatt cccgggagct tacatcagta agtgaccggg atgagcgagc gaagataacg
    26101 catctgcggc gcgaaatatg aagggggaga gcccttatag accaggtagt acacgtttgg
    26161 ttagggggcc tgcatatggc cccctttttc acttttatat ctgtgcggtt taatgccggg
    26221 cagatcacat ctccgaggat tttagaatgg ctgaaattac cgcatccctg gtaaaagagc
    26281 tgcgtgagcg tactggcgca ggcatgatgg attgcaaaaa agcactgact gaagctaacg
    26341 gcgacatcga gctggcaatc gaaaacatgc gtaagtccgg tgctattaaa gcagcgaaaa
    26401 aagcaggcaa cgttgctgct gacggcgtga tcaaaaccaa aatcgacggc aactacggca
    26461 tcattctgga agttaactgc cagactgact tcgttgcaaa agacgctggt ttccaggcgt
    26521 tcgcagacaa agttctggac gcagctgttg ctggcaaaat cactgacgtt gaagttctga
    26581 aagcacagtt cgaagaagaa cgtgttgcgc tggtagcgaa aattggtgaa aacatcaaca
    26641 ttcgccgcgt tgctgcgctg gaaggcgacg ttctgggttc ttatcagcac ggtgcgcgta
    26701 tcggcgttct ggttgctgct aaaggcgctg acgaagagct ggttaaacac atcgctatgc
    26761 acgttgctgc aagcaagcca gaattcatca aaccggaaga cgtatccgct gaagtggtag
    26821 aaaaagaata ccaggtacag ctggatatcg cgatgcagtc tggtaagccg aaagaaatcg
    26881 cagagaaaat ggttgaaggc cgcatgaaga aattcaccgg cgaagtttct ctgaccggtc
    26941 agccgttcgt tatggaacca agcaaaactg ttggtcagct gctgaaagag cataacgctg
    27001 aagtgactgg cttcatccgc ttcgaagtgg gtgaaggcat cgagaaagtt gagactgact
    27061 ttgcagcaga agttgctgcg atgtccaagc agtcttaatt atcaaaaagg agccgcctga
    27121 gggcggcttc tttttgtgcc catcttgtaa attcagctaa cccttgtggg gctgcgctga
    27181 aaagcgacgt acaatgtcgc tagtattaat tcatttcaat cgttgacagt ctcaggaaag
    27241 aaacatggct accaatgcaa aacccgtcta taaacgcatt ctgcttaagt tgagtggcga
    27301 agctctgcag ggcactgaag gcttcggtat tgatgcaagc atactggatc gtatggctca
    27361 ggaaatcaaa gaactggttg aactgggtat tcaggttggt gtggtgattg gtgggggtaa
    27421 cctgttccgt ggcgctggtc tggcgaaagc gggtatgaac cgcgttgtgg gcgaccacat
    27481 ggggatgctg gcgaccgtaa tgaacggcct ggcaatgcgt gatgcactgc accgcgccta
    27541 tgtgaacgct cgtctgatgt ccgctattcc attgaatggc gtgtgcgaca gctacagctg
    27601 ggcagaagct atcagcctgt tgcgcaacaa ccgtgtggtg atcctctccg ccggtacagg
    27661 taacccgttc tttaccaccg actcagcagc ttgcctgcgt ggtatcgaaa ttgaagccga
    27721 tgtggtgctg aaagcaacca aagttgacgg cgtgtttacc gctgatccgg cgaaagatcc
    27781 aaccgcaacc atgtacgagc aactgactta cagcgaagtg ctggaaaaag agctgaaagt
    27841 catggacctg gcggccttca cgctggctcg tgaccataaa ttaccgattc gtgttttcaa
    27901 tatgaacaaa ccgggtgcgc tgcgccgtgt ggtaatgggt gaaaaagaag ggactttaat
    27961 cacggaataa ttcccgtgat ggataaataa gggtaagatt ccgcgtaagt atcgcggggg
    28021 cgtaagtctg gttataaggc gttattgttg caggcagttt ggtcacggcc agcgcgcagc
    28081 aaccggagcg tacaaaagta cgtgaggatg gcgagcactg cccggggcca aaatggcaaa
    28141 taaaatagcc taataatcca gacgattacc cgtaatatgt ttaatcaggg ctatacttag
    28201 cacacttcca ctgtgtgtga ctgtctggtc tgactgagac aagttttcaa ggattcgtaa
    28261 cgtgattagc gatatcagaa aagatgctga agtacgcatg gacaaatgcg tagaagcgtt
    28321 caaaacccaa atcagcaaaa tacgcacggg tcgtgcttct cccagcctgc tggatggcat
    28381 tgtcgtggaa tattacggca cgccgacgcc gctgcgtcag ctggcaagcg taacggtaga
    28441 agattcccgt acactgaaaa tcaacgtgtt tgatcgttca atgtctccgg ccgttgaaaa
    28501 agcgattatg gcgtccgatc ttggcctgaa cccgaactct gcgggtagcg acatccgtgt
    28561 tccgctgccg ccgctgacgg aagaacgtcg taaagatctg accaaaatcg ttcgtggtga
    28621 agcagaacaa gcgcgtgttg cagtacgtaa cgtgcgtcgt gacgcgaacg acaaagtgaa
    28681 agcactgttg aaagataaag agatcagcga agacgacgat cgccgttctc aggacgatgt
    28741 acagaaactg actgatgctg caatcaagaa aattgaagcg gcgctggcag acaaagaagc
    28801 agaactgatg cagttctgat ttcttgaacg acaaaaacgc cgctcagtag atccttgcgg
    28861 atcggctggc ggcgttttgc tttttattct gtctcaactc tggatgtttc atgaagcaac
    28921 tcaccattct gggctcgacc ggctcgattg gttgcagcac gctggacgtg gtgcgccata
    28981 atcccgaaca cttccgcgta gttgcgctgg tggcaggcaa aaatgtcact cgcatggtag
    29041 aacagtgcct ggaattctct ccccgctatg ccgtaatgga cgatgaagcg agtgcgaaac
    29101 ttcttaaaac gatgctacag caacagggta gccgcaccga agtcttaagt gggcaacaag
    29161 ccgcttgcga tatggcagcg cttgaggatg ttgatcaggt gatggcagcc attgttggcg
    29221 ctgctgggct gttacctacg cttgctgcga tccgcgcggg taaaaccatt ttgctggcca
    29281 ataaagaatc actggttacc tgcggacgtc tgtttatgga cgccgtaaag cagagcaaag
    29341 cgcaattgtt accggtcgat agcgaacata acgccatttt tcagagttta ccgcaaccta
    29401 tccagcataa tctgggatac gctgaccttg agcaaaatgg cgtggtgtcc attttactta
    29461 ccgggtctgg tggccctttc cgtgagacgc cattgcgcga tttggcaaca atgacgccgg
    29521 atcaagcctg ccgtcatccg aactggtcga tggggcgtaa aatttctgtc gattcggcta
    29581 ccatgatgaa caaaggtctg gaatacattg aagcgcgttg gctgtttaac gccagcgcca
    29641 gccagatgga agtgctgatt cacccgcagt cagtgattca ctcaatggtg cgctatcagg
    29701 acggcagtgt tctggcgcag ctgggggaac cggatatgcg tacgccaatt gcccacacca
    29761 tggcatggcc gaatcgcgtg aactctggcg tgaagccgct cgatttttgc aaactaagtg
    29821 cgttgacatt tgccgcaccg gattatgatc gttatccatg cctgaaactg gcgatggagg
    29881 cgttcgaaca aggccaggca gcgacgacag cattgaatgc cgcaaacgaa atcaccgttg
    29941 ctgcttttct tgcgcaacaa atccgcttta cggatatcgc tgcgttgaat ttatccgtac
    30001 tggaaaaaat ggatatgcgc gaaccacaat gtgtggacga tgtgttatct gttgatgcga
    30061 acgcgcgtga agtcgccaga aaagaggtga tgcgtctcgc aagctgagga taatccggct
    30121 acagagagtc gcgctatttg ttagcgtagg gcttcagtga tatagtctgc gccatctgat
    30181 cgtaagtagt tggctttata aggtcaggta tgccgtggtt ttacacggct tttttttgta
    30241 taggcttcag tattcctgag taccgtaaac cctgtcaggg aataaaaaac gcgtgatgtt
    30301 gtctgctact caaccactta gcgaaaaatt gccagcgcat ggctgccgtc atgttgcgat
    30361 cattatggac ggcaatggtc gctgggcaaa aaagcaaggg aagattcgtg cctttgggca
    30421 taaagccggg gcaaaatccg tccgccgggc tgtctctttt gcggccaaca acggtattga
    30481 ggcgttaacg ctgtatgcct ttagtagtga aaactggaac cgaccagcgc aggaagtcag
    30541 tgcgttaatg gaactgtttg tgtgggcgct cgatagcgaa gtaaaaagtc tgcaccgaca
    30601 taacgtgcgt ctgcgtatta ttggcgatac cagtcgcttt aactcgcgtt tgcaagaacg
    30661 tattcgtaaa tctgaagcgc taacagccgg gaataccggt ctgacgctga atattgcggc
    30721 gaactacggt ggacgttggg atatagtcca gggagtcagg caactggctg aaaaggtgca
    30781 gcaaggaaac ctgcaaccag atcagataga tgaagagatg ctaaaccagc atgtctgtat
    30841 gcatgaactg gcccctgtag atttagtaat taggactggg ggggagcatc gcattagtaa
    30901 ctttttgctt tggcaaattg cctatgccga actttacttt acagatgttc tctggcccga
    30961 tttcgatgaa caagactttg aaggggcgtt aaatgccttt gctaatcgag agcgtcgttt
    31021 cggcggcacc gagcccggtg atgaaacagc ctgatggggg tcgcttttgc tgaagtatcg
    31081 cctgatatct gcttttgtgt taatacccgt cgtcatcgcg gcgttgtttc tgttgccgcc
    31141 ggtggggttc gccattgtaa cgctggtggt ctgcatgctg gcagcgtggg aatggggaca
    31201 gcttagcggt tttaccactc gttcgcagcg agtatggttg gcggtgttat gcgggttatt
    31261 gttggcgctg atgctttttc tgttgccgga atatcaccga aatattcatc aaccgctggt
    31321 tgaaatctca ctttgggctt cgctgggttg gtggattgtc gcgctattgc tggtgctgtt
    31381 ttacccaggt tccgcagcaa tctggcgtaa ctctaaaaca ttgcgcctta tttttggcgt
    31441 gctaaccatt gttcccttct tctggggcat gctggcgtta cgggcctggc actatgacga
    31501 gaatcattac agtggcgcaa tatggctgct ctatgtcatg atcctggtat ggggcgctga
    31561 ctccggcgca tatatgtttg gcaaattgtt tggtaaacat aagctggcac cgaaggtttc
    31621 tccgggtaaa acctggcaag gctttatcgg tggactcgct actgcagcgg taatctcatg
    31681 gggttatggc atgtgggcga atctcgacgt cgctcccgtc accttactca tttgctctat
    31741 tgtcgcagcg ttagcctcag tgctcggcga tctgaccgag agtatgttta agcgtgaagc
    31801 aggaattaag gacagcggtc atttaattcc aggacacggt ggtattttag atcgtattga
    31861 tagcctgacg gctgcggtac cggtctttgc ttgcttgttg ttactggtat tcaggacgct
    31921 ttaacggaag gtaatatgct gagttttctc tgggatttgg cttcgttcat cgttgcactg
    31981 ggtgtactta tcaccgtgca tgaatttggt catttctggg ttgcccggcg ttgtggtgtt
    32041 cgcgttgagc gtttctcaat agggtttggt aaggcgctct ggcggcgaac tgataagctc
    32101 ggcaccgaat atgttatcgc cctgatcccg ttgggcggtt atgtcaaaat gctggatgag
    32161 cgcgcagaac cggtcgttcc ggaactccgc caccatgcct tcaataataa atctgtcggc
    32221 caacgagcgg cgattattgc cgcaggtccg gttgcaaact tcatttttgc tatctttgcc
    32281 tactggctgg tttttattat tggtgtgcct ggcgtacgtc cggtggttgg cgaaatagca
    32341 gccaattcga tagctgcgga agcacaaatt gcaccaggta cggaactaaa agccgtagat
    32401 ggtatcgaaa cgcctgattg ggatgccgtg cgtttgcagt tggtcgataa aattggcgat
    32461 gaaagcacca ccattacagt agcgccattt ggcagcgacc aacggcggga tgtaaagctc
    32521 gatttacgtc actgggcgtt tgagcctgat aaagaagatc cggtatcttc gctggggatt
    32581 cgtcctcgtg ggccgcaaat tgaacctgta ctggaaaatg tgcagccaaa ctcggcggca
    32641 agcaaggcag gtttgcaagc aggcgacagg atcgttaaag tcgatggtca gcccttaacg
    32701 cagtgggtga cctttgtgat gcttgtccgg gataacccgg gtaaatcctt agcgttagaa
    32761 atcgaaaggc aggggagtcc cttgtctttg acattaatcc cggagagtaa accgggtaat
    32821 ggtaaagcga ttggttttgt cggtattgag ccgaaagtca ttcctttgcc agatgagtat
    32881 aaagttgtac gccagtatgg gccgttcaac gccatcgtcg aagccacgga caaaacgtgg
    32941 cagctgatga agctgacggt cagtatgctg ggaaaattga tcaccggtga tgtgaaactg
    33001 aacaacctca gtgggccgat ctctatcgcc aagggggctg ggatgacagc ggaactcggg
    33061 gttgtttatt acctgccgtt tcttgcgctt attagcgtga acttagggat aattaacctg
    33121 tttccgttgc ccgtacttga cggggggcat ctgctgttcc ttgcgatcga aaagatcaag
    33181 ggcggaccgg tatccgagcg ggttcaagac ttttgttatc gcattggctc gattctgctg
    33241 gtgctgttaa tggggcttgc acttttcaat gatttctctc ggttatgaga gttagttagg
    33301 aagaacgcat aataacgatg gcgatgaaaa agttgctcat agcgtcgctg ctgtttagca
    33361 gcgccaccgt atacggtgct gaagggttcg tagtgaaaga tattcatttc gaaggccttc
    33421 agcgtgtcgc cgttggtgcg gccctcctca gtatgccggt gcgcacaggc gacacggtta
    33481 atgatgaaga tatcagtaat accattcgcg ctctgtttgc taccggcaac tttgaggatg
    33541 ttcgcgtcct tcgtgatggt gatacccttc tggttcaggt aaaagaacgt ccgaccattg
    33601 ccagcattac tttctccggt aacaaatcgg tgaaagatga catgctgaag caaaacctcg
    33661 aggcttctgg tgtgcgtgtg ggcgaatccc tcgatcgcac caccattgcc gatatcgaga
    33721 aaggtctgga agacttctac tacagcgtcg gtaaatatag cgccagcgta aaagctgtcg
    33781 tgaccccgct gccgcgcaac cgtgttgacc taaaactggt gttccaggaa ggtgtgtcag
    33841 ctgaaatcca gcaaattaac attgttggta accatgcttt caccaccgac gaactgatct
    33901 ctcatttcca actgcgtgac gaagtgccgt ggtggaacgt ggtaggcgat cgtaaatacc
    33961 agaaacagaa actggcgggc gaccttgaaa ccctgcgcag ctactatctg gatcgcggtt
    34021 atgcccgttt caacatcgac tctacccagg tcagtctgac gccagataaa aaaggtattt
    34081 acgtcacggt gaacatcacc gaaggcgatc agtacaagct ttctggcgtt gaagtgagcg
    34141 gcaaccttgc cgggcactcc gctgaaattg agcagctgac taagatcgag ccgggtgagc
    34201 tgtataacgg caccaaagtg accaagatgg aagatgacat caaaaagctt ctcggtcgct
    34261 atggttatgc ctatccgcgc gtacagtcga tgcccgaaat taacgatgcc gacaaaaccg
    34321 ttaaattacg tgtgaacgtt gatgcgggta accgtttcta cgtgcgtaag atccgttttg
    34381 aaggtaacga tacctcgaaa gatgccgtcc tgcgtcgcga aatgcgtcag atggaaggtg
    34441 catggctggg gagcgatctg gtcgatcagg gtaaggagcg tctgaatcgt ctgggcttct
    34501 ttgaaactgt cgataccgat acccaacgtg ttccgggtag cccggaccag gttgatgtcg
    34561 tctacaaggt aaaagagcgc aacaccggta gcttcaactt tggtattggt tacggtactg
    34621 aaagtggcgt gagcttccag gctggtgtgc agcaggataa ctggttaggt acaggttatg
    34681 ctgttggtat caacgggacc aaaaacgatt accagaccta tgctgaactg tcggtaacca
    34741 acccgtactt caccgtagat ggcgtaagcc tcggtggtcg tctcttctat aatgacttcc
    34801 aggcagatga cgccgacctg tccgactata ccaacaagag ttatggtaca gacgtgacgt
    34861 tgggcttccc gattaacgaa tataactcgc tgcgtgcagg tctgggttat gtacataact
    34921 ccctgtccaa catgcagcct caggttgcga tgtggcgtta tctgtactct atgggtgaac
    34981 atccgagcac ctctgatcag gataacagct tcaaaacgga cgacttcacg ttcaactatg
    35041 gttggaccta taacaagctt gaccgtggtt acttcccgac agatggttca cgtgtcaacc
    35101 tgaccggtaa agtgaccatt cctggatcgg ataacgaata ctacaaagtg acgttagaca
    35161 cggcgactta tgtgccgatc gatgacgatc acaaatgggt tgttctgggg cgtacccgct
    35221 ggggttatgg tgatggttta ggcggcaaag agatgccgtt ctacgagaac ttctatgccg
    35281 gtggttccag caccgtgcgt ggcttccagt ccaataccat tggtccgaaa gcagtttact
    35341 tcccgcatca ggccagtaat tatgatccgg actatgatta cgaatgtgcg actcaggacg
    35401 gcgcgaaaga cctgtgtaaa tcggatgatg ctgtaggcgg taacgccatg gcggttgcca
    35461 gcctcgagtt catcaccccg acgccgttta ttagcgataa gtatgctaac tcggttcgta
    35521 cttccttctt ctgggatatg ggtaccgttt gggatacaaa ctgggattcc agccaatatt
    35581 ctggatatcc ggactatagt gatccaagca atatccgtat gtctgcgggt atcgcattac
    35641 aatggatgtc cccattgggg ccgttggtgt tctcctacgc ccagccgttc aaaaagtacg
    35701 atggagacaa ggcagaacag ttccagttta acatcggtaa aacctggtaa gtgttctcca
    35761 caaaggaatg tagtggtagt gtagcgatga ctttaggcga tcaatataag atcgccgggc
    35821 cacgcaaaga actgcaccct ccggtgcaaa tgggatggta aggagtttat tgtgaaaaag
    35881 tggttattag ctgcaggtct cggtttagca ctggcaactt ctgctcaggc ggctgacaaa
    35941 attgcaatcg tcaacatggg cagcctgttc cagcaggtag cgcagaaaac cggtgtttct
    36001 aacacgctgg aaaatgagtt caaaggccgt gccagcgaac tgcagcgtat ggaaaccgat
    36061 ctgcaggcta aaatgaaaaa gctgcagtcc atgaaagcgg gcagcgatcg cactaagctg
    36121 gaaaaagacg tgatggctca gcgccagact tttgctcaga aagcgcaggc ttttgagcag
    36181 gatcgcgcac gtcgttccaa cgaagaacgc ggcaaactgg ttactcgtat ccagactgct
    36241 gtgaaatccg ttgccaacag ccaggatatc gatctggttg ttgatgcaaa cgccgttgct
    36301 tacaacagca gcgatgtaaa agacatcact gccgacgtac tgaaacaggt taaataagta
    36361 atgccttcaa ttcgactggc tgatttagcg cagcagttgg atgcagaact acacggtgat
    36421 ggcgatatcg tcatcaccgg cgttgcgtcc atgcaatctg cacaaacagg tcacattacg
    36481 ttcatggtta acccaaaata ccgtgagcat ttaggcttgt gccaggcgtc cgcggttgtc
    36541 atgacccagg acgatcttcc tttcgcgaaa agtgccgcac tggtagtgaa gaatccctac
    36601 ctgacttacg cgcgcatggc gcaaatttta gataccacgc cgcagcccgc gcagaacatt
    36661 gcacccagtg cggtgatcga cgcgacggcg aagctgggta acaacgtatc gattggcgct
    36721 aacgcggtga ttgagtccgg cgttgaactg ggcgataacg tgattatcgg tgccggttgc
    36781 ttcgtaggta aaaacagcaa aatcggtgca ggttcgcgtc tctgggcgaa cgtaaccatt
    36841 taccatgaga tccagatcgg tcagaattgc ctgatccagt ccggaacagt ggtaggcgca
    36901 gacggctttg gttatgccaa cgatcgtggt aactgggtga agatcccaca gattggtcgc
    36961 gtaattattg gcgatcgcgt ggagatcggt gcctgcacaa ccatcgatcg cggcgcgctg
    37021 gatgacacta ttattggcaa tggcgtgatc attgataacc agtgccagat tgcacataac
    37081 gtcgtgattg gcgacaatac ggcggttgcc ggtggcgtca ttatggcggg cagcctgaaa
    37141 attggtcgtt actgcatgat cggcggagcc agcgtaatca acgggcatat ggaaatatgc
    37201 gacaaagtga cggttacggg catgggtatg gtgatgcgtc ccatcactga accaggcgtc
    37261 tattcctcag gcattccgct gcaacccaac aaagtctggc gcaaaaccgc tgcactggtg
    37321 atgaacattg atgacatgag caagcgtctg aaatcgcttg agcgcaaggt taatcaacaa
    37381 gactaacgtt ccatcttttg ttcgccaaac tttacggcct gtctcattct tacgattgcg
    37441 gcaggccgtg ttattattgt cgtttcttat attttgacag gaagagtatc ttgactacta
    37501 acactcatac tctgcagatt gaagagattt tagaacttct gccgcaccgt ttcccgttct
    37561 tactggtgga tcgcgtgctg gattttgaag aaggtcgttt tctgcgcgca gtaaaaaatg
    37621 tctctgtcaa tgagccattc ttccagggcc atttccctgg aaaaccgatt ttcccgggtg
    37681 tgctgattct ggaagcaatg gcacaggcaa caggtattct ggcgtttaaa agcgtaggaa
    37741 aactggaacc gggtgagctg tactacttcg ctggtattga cgaagcgcgc ttcaagcgcc
    37801 cggtcgtgcc tggcgatcaa atgatcatgg aagtcacttt cgaaaaaacg cgccgcggcc
    37861 tgacccgttt taaaggggtt gctctggtcg atggtaaagt agtttgcgaa gcaacgatga
    37921 tgtgtgctcg tagccgggag gcctgatacg tgattgataa atccgccttt gtgcatccaa
    37981 ccgccattgt ggaagagggc gcgtcaattg gcgcgaacgc acacattggt cctttttgta
    38041 tcgttggacc ccatgtcgaa attggtgagg gtaccgtact gaaatctcac gttgtcgtga
    38101 atggtcatac taaaattggc cgcgataatg agatttatca gttcgcctcc atcggcgaag
    38161 ttaaccagga tctgaaatat gctggcgaac cgacccgtgt ggaaatcggc gatcgtaacc
    38221 gcattcgcga aagcgtcacc attcatcgtg gcacagtcca gggcggtgga ttgacgaagg
    38281 tgggcagcga caacttactg atgatcaacg cgcacattgc gcacgattgt acggtaggta
    38341 accgctgtat tctcgccaac aacgcaacgc tggcgggtca cgtatcggtt gacgacttcg
    38401 cgatcatcgg cggcatgacc gcagtccatc agttctgcat cattggtgcg cacgtgatgg
    38461 ttggcggctg ctccggtgtg gcgcaggacg tccctcctta tgtcattgcg cagggtaacc
    38521 acgcaacgcc gttcggtgtc aatatcgaag ggctgaagcg ccgcggattc agccgtgagg
    38581 cgattaccgc tatccgcaat gcgtataagc tgatttatcg tagcggtaaa acgctcgatg
    38641 aagtgaaacc ggaaattgct gaactggcgg aaacatatcc ggaagtgaaa gcctttaccg
    38701 atttctttgc acgctcaacg cgcggtctga ttcgttaatg actgaacagc gtccattaac
    38761 gattgccctg gtcgccggag aaacctccgg cgatatcctg ggggccggtt taatccgcgc
    38821 tctgaaagaa catgtgccca acgcccgctt tgttggtgtt gccgggccac gaatgcaggc
    38881 tgaaggctgc gaagcctggt acgaaatgga agaactggcg gtgatgggca ttgttgaagt
    38941 gctcggtcgt ctgcgtcgct tactgcatat tcgtgccgat ctgacaaagc gttttggcga
    39001 actgaagcca gatgtttttg ttggtattga tgcgcctgac ttcaatatta ctcttgaagg
    39061 taacctcaaa aagcagggta tcaaaaccat tcattacgtc agtccgtcag tctgggcgtg
    39121 gcgacagaaa cgtgttttca aaataggcag agccaccgat ctggtgctcg catttctgcc
    39181 tttcgaaaaa gcgttttatg acaaatacaa cgtaccgtgc cgctttatcg gtcataccat
    39241 ggctgatgcc atgccattag atccagataa aaatgccgcc cgtgatgtgc tggggatccc
    39301 tcacgatgcc cactgcctgg cgttgctacc ggggagccgt ggtgcagaag ttgaaatgct
    39361 tagtgccgat ttcctgaaaa cggcccagct tttgcgccag acatatccgg atctcgaaat
    39421 cgtggtgcca ctggtgaatg ccaaacgccg cgagcagttt gaacgcatca aagctgaagt
    39481 cgcgccagac ctttcagttc atttgctgga tgggatgggc cgtgaggcga tggtcgccag
    39541 cgatgcggcg ctactggcgt cgggtacggc agccctggag tgtatgctgg cgaaatgccc
    39601 gatggtggtg ggatatcgca tgaagccttt taccttctgg ttggcgaagc ggctggtgaa
    39661 aactgattat gtctcgctgc caaatctgct ggcgggcaga gagttagtca aagaattatt
    39721 gcaggaagag tgtgagccgc aaaaactggc tgcggcgctg ttaccgctgt tggcgaacgg
    39781 gaaaaccagc cacgcgatgc acgatacctt ccgtgaactg catcagcaga tccgctgcaa
    39841 tgccgatgag caggcggcac aagccgttct ggagttagca caatgatcga atttgtttat
    39901 ccgcacacgc agctggttgc gggtgtggat gaagtcggac gcgggccgtt agttggcgcg
    39961 gtcgtcaccg ctgcggtgat ccttgacccg gcgcgcccga ttgccgggct gaatgattcc
    40021 aaaaagctga gcgaaaaacg ccgtctggcg ctctatgaag agatcaaaga gaaagcgttg
    40081 agctggagtc tgggccgcgc ggaaccccac gaaatcgacg agctgaacat tcttcatgcg
    40141 accatgctgg cgatgcagcg tgccgtcgct gggctgcata ttgcgccgga atatgtgttg
    40201 attgatggta accgctgccc gaaattaccg atgcctgcga tggctgtggt gaaaggcgat
    40261 agccgcgtac cggaaatcag tgccgcgtct atcctggcga aagtgacgcg tgacgccgaa
    40321 atggcggcgc tggatattgt tttcccgcaa tatggttttg cccaacacaa agggtaccca
    40381 accgcttttc atctggaaaa actggctgaa cacggcgcga ccgaacacca tcggcgcagc
    40441 tttgggcctg tcaaacgcgc actgggactt gcgtcctgat tcttgtgtcg agattaagta
    40501 aaccggaatc tgaagatgtc tgaaccacgt ttcgtacacc tgcgggtgca cagcgactac
    40561 tcgatgatcg atggcctggc caaaaccgca ccgttggtaa aaaaggcggc ggcgttgggt
    40621 atgccagcac tggcgatcac cgatttcacc aacctttgtg gtctggtgaa gttctacgga
    40681 gcgggacatg gcgcagggat taagcctatc gtcggggcag attttaacgt ccagtgcgac
    40741 ctgctgggtg atgagttaac ccacctgacg gtactggcgg cgaacaatac cggctatcag
    40801 aatctgacgt tgctgatctc aaaagcgtat cagcgcgggt acggtgccgc cgggccgatc
    40861 atcgatcgcg actggcttat cgaattaaac gaagggttga tccttctttc cggcggacgc
    40921 atgggcgacg tcggacgcag tcttttgcgt ggtaacagcg cgctggtaga tgagtgtgtc
    40981 gcgttttatg aagaacactt cccggatcgc tattttctcg agctgatccg caccggcagg
    41041 ccggatgaag aaagctatct gcacgcggcg gtggaactgg cggaagcgcg cggtttgccc
    41101 gtcgtggcga ccaacgacgt gcgctttatc gacagcagcg actttgacgc acacgaaatc
    41161 cgcgtcgcga tccacgacgg ctttaccctc gacgatccta aacgcccgcg taactattcg
    41221 ccgcagcaat atatgcgtag cgaagaggag atgtgtgagc tgtttgccga catccccgaa
    41281 gcccttgcca acaccgttga gatcgccaaa cgctgtaacg taaccgtgcg tcttggtgaa
    41341 tacttcctgc cgcagttccc gaccggggac atgagcaccg aagattatct ggtcaagcgt
    41401 gcaaaagagg gcctggaaga gcgtctggcc tttttattcc ctgatgagga agaacgtctt
    41461 aagcgccgcc cggaatatga cgaacgtctg gagactgaac ttcaggttat caaccagatg
    41521 ggcttcccgg gctacttcct catcgttatg gaatttatcc agtggtcgaa agataacggc
    41581 gtaccggtag ggccaggccg tggctccggt gcgggttcac tggtggccta cgcgctgaaa
    41641 atcaccgacc tcgatccgct ggaatttgac ctgctgttcg aacgtttcct taacccggaa
    41701 cgtgtctcca tgcctgactt cgacgttgac ttctgtatgg agaaacgcga tcaggttatc
    41761 gagcacgtag cggacatgta cggtcgtgat gcggtatcgc agatcatcac cttcggtaca
    41821 atggcggcga aagcggtgat ccgcgacgta ggccgcgtgc tggggcatcc gtacggcttt
    41881 gtcgatcgta tctcgaaact gatcccgccc gatccgggga tgacgctggc gaaagcgttt
    41941 gaagccgagc cgcagctgcc ggaaatctac gaagcggatg aagaagttaa ggcgctgatc
    42001 gacatggcgc gcaaactgga aggggtcacc cgtaacgccg gtaagcacgc cggtggggtg
    42061 gttatcgcgc cgaccaaaat taccgatttt gcgccgcttt actgcgatga agagggcaaa
    42121 catccggtca cccagtttga taaaagcgac gttgaatacg ccggactggt gaagttcgac
    42181 ttccttggtt tgcgtacgct caccatcatc aactgggcgc tggagatgat caacaagcgg
    42241 cgggcgaaga atggcgagcc gccgctggat atcgctgcga tcccgctgga tgataagaaa
    42301 agcttcgaca tgctgcaacg ctcggaaacc acggcggtat tccagcttga atcgcgcggc
    42361 atgaaggacc tgatcaagcg tctacaacct gactgcttcg aagatatgat cgccctagtg
    42421 gcactgttcc gccccggtcc gttgcaatca gggatggtgg ataactttat cgaccgtaaa
    42481 catggtcgtg aagagatctc ctatccggac gtacagtggc agcatgaaag cctgaaaccg
    42541 gtactggagc caacctacgg cattatcctg tatcaggaac aggtcatgca gattgcgcag
    42601 gtgctttctg gttataccct cggtggcgcg gatatgctgc gtcgtgcgat gggtaagaaa
    42661 aagccggaag agatggctaa gcaacgttct gtatttgctg aaggtgcaga aaagaacgga
    42721 atcaacgctg aactggcgat gaaaatcttc gacctggtgg agaaattcgc tggttacgga
    42781 tttaacaaat cgcactctgc ggcctatgct ttggtgtcat atcaaacgtt atggctgaaa
    42841 gcgcactatc ctgcggagtt tatggcggcg gtaatgaccg ccgatatgga caacaccgag
    42901 aaggtggtgg gtctggtgga tgagtgctgg cggatggggc tgaaaatcct gccaccagat
    42961 ataaactccg gtctttacca tttccacgtc aacgacgacg gcgaaatcgt gtatggtatt
    43021 ggcgcgatca aaggggtcgg tgaaggtccg attgaggcca tcatcgaagc ccgtaataaa
    43081 ggcggctact tccgcgaact gtttgatctc tgcgcccgta ccgacaccaa aaagttgaac
    43141 cgtcgcgtgc tggaaaaact gatcatgtcc ggggcgtttg accgtcttgg gccacatcgc
    43201 gcagcgctga tgaactcgct gggcgatgcg ttaaaagcgg cagatcaaca cgcgaaagcg
    43261 gaagctatcg gtcaggccga tatgttcggc gtgctggccg aagagccgga acaaattgaa
    43321 caatcctacg ccagctgcca accgtggccg gagcaggtgg tattagatgg ggaacgtgaa
    43381 acgttaggcc tgtacctgac cggacaccct atcaaccagt atttaaaaga gattgagcgt
    43441 tatgtcggag gcgtaaggct gaaagacatg cacccgacag aacgtggtaa agtcatcacg
    43501 gctgcggggc tcgttgttgc cgcgcgggtt atggtcacca agcgcggcaa tcgtatcggt
    43561 atctgcacgc tggatgaccg ttccgggcgg ctggaagtga tgttgtttac tgacgccctg
    43621 gataaatacc agcaattgct ggaaaaagac cgcatactta tcgtcagcgg acaggtcagc
    43681 tttgatgact tcagcggtgg gcttaaaatg accgctcgcg aagtgatgga tattgacgaa
    43741 gcccgggaaa aatatgctcg cgggcttgct atctcgctga cggacaggca aattgatgac
    43801 cagcttttaa accgactccg tcagtctctg gaaccccacc gctctgggac aattccagta
    43861 catctctact atcagagggc ggatgcacgc gcgcggttgc gttttggcgc gacgtggcgt
    43921 gtctctccga gcgatcgttt attaaacgat ctccgtggcc tcattggttc ggagcaggtg
    43981 gaactggagt ttgactaata caggaatact atgagtctga atttccttga ttttgaacag
    44041 ccgattgcag agctggaagc gaaaatcgat tctctgactg cggttagccg tcaggatgag
    44101 aaactggata ttaacatcga tgaagaagtg catcgtctgc gtgaaaaaag cgtagaactg
    44161 acacgtaaaa tcttcgccga tctcggtgca tggcagattg cgcaactggc acgccatcca
    44221 cagcgtcctt ataccctgga ttacgttcgc ctggcatttg atgaatttga cgaactggct
    44281 ggcgaccgcg cgtatgcaga cgataaagct atcgtcggtg gtatcgcccg tctcgatggt
    44341 cgtccggtga tgatcattgg tcatcaaaaa ggtcgtgaaa ccaaagaaaa aattcgccgt
    44401 aactttggta tgccagcgcc agaaggttac cgcaaagcac tgcgtctgat gcaaatggct
    44461 gaacgcttta agatgcctat catcaccttt atcgacaccc cgggggctta tcctggcgtg
    44521 ggcgcagaag agcgtggtca gtctgaagcc attgcacgca acctgcgtga aatgtctcgc
    44581 ctcggcgtac cggtagtttg tacggttatc ggtgaaggtg gttctggcgg tgcgctggcg
    44641 attggcgtgg gcgataaagt gaatatgctg caatacagca cctattccgt tatctcgccg
    44701 gaaggttgtg cgtccattct gtggaagagc gccgacaaag cgccgctggc ggctgaagcg
    44761 atgggtatca ttgctccgcg tctgaaagaa ctgaaactga tcgactccat catcccggaa
    44821 ccactgggtg gtgctcaccg taacccggaa gcgatggcgg catcgttgaa agcgcaactg
    44881 ctggcggatc tggccgatct cgacgtgtta agcactgaag atttaaaaaa tcgtcgttat
    44941 cagcgcctga tgagctacgg ttacgcgtaa ttcgcaaaag ttctgaaaaa gggtcacttc
    45001 ggtggccctt ttttatcgcc acggtttgag caggctatga ttaaggaagg attttccagg
    45061 aggaacacat gaacatcatt gccattatgg gaccgcatgg cgtcttttat aaagatgagc
    45121 ccatcaaaga actggagtcg gcgctggtgg cgcaaggctt tcagattatc tggccacaaa
    45181 acagcgttga tttgctgaaa tttatcgaac ataaccctcg aatttgcggc gtgatttttg
    45241 actgggatga gtacagtctc gatttatgta gcgatatcaa tcagcttaat gaatatctcc
    45301 cgctttatgc cttcatcaac acccactcga cgatggatgt cagcgtgcag gatatgcgga
    45361 tggcgctctg gttttttgaa tatgcgctgg ggcaggcgga agatatcgcc attcgtatgc
    45421 gtcagtacac cgacgaatat cttgataaca ttacaccgcc gttcacgaaa gccttgttta
    45481 cctacgtcaa agagcggaag tacacctttt gtacgccggg gcatatgggc ggcaccgcat
    45541 atcaaaaaag cccggttggc tgtctgtttt atgatttttt cggcgggaat actcttaagg
    45601 ctgatgtctc tatttcggtc accgagcttg gttcgttgct cgaccacacc gggccacacc
    45661 tggaagcgga agagtacatc gcgcggactt ttggcgcgga acagagttat atcgttacca
    45721 acggaacatc gacgtcgaac aaaattgtgg gtatgtacgc cgcgccatcc ggcagtacgc
    45781 tgttgatcga ccgcaattgt cataaatcgc tggcgcatct gttgatgatg aacgatgtag
    45841 tgccagtctg gctgaaaccg acgcgtaatg cgttggggat tcttggtggg atcccgcgcc
    45901 gtgaatttac tcgcgacagc atcgaagaga aagtcgctgc taccacgcaa gcacaatggc
    45961 cggttcatgc ggtgatcacc aactccacct atgatggctt gctctacaac accgactgga
    46021 tcaaacagac gctggatgtc ccgtcgattc acttcgattc tgcctgggtg ccgtacaccc
    46081 attttcatcc gatctaccag ggtaaaagtg gtatgagcgg cgagcgtgtt gcgggaaaag
    46141 tgatcttcga aacgcaatcg acccacaaaa tgctggcggc gttatcgcag gcttcgctga
    46201 tccacattaa aggcgagtat gacgaagagg cctttaacga agcctttatg atgcatacca
    46261 ccacctcgcc cagttatccc attgttgctt cggttgagac ggcggcggcg atgctgcgtg
    46321 gtaatccggg caaacggctg attaaccgtt cagtagaacg agctctgcat tttcgcaaag
    46381 aggtccagcg gctgcgggaa gagtctgacg gttggttttt cgatatctgg caaccgccgc
    46441 aggtggatga agccgaatgc tggcccgttg cgcctggcga acagtggcac ggctttaacg
    46501 atgcggatgc cgatcatatg tttctcgatc cggttaaagt cactattttg acaccgggga
    46561 tggacgagca gggcaatatg agcgaggagg ggatcccggc ggcgctggta gcaaaattcc
    46621 tcgacgaacg tgggatcgta gtagagaaaa ccggccctta taacctgctg tttctcttta
    46681 gtattggcat cgataaaacc aaagcaatgg gattattgcg tgggttgacg gaattcaaac
    46741 gctcttacga tctcaacctg cggatcaaaa atatgctacc cgatctctat gcagaagatc
    46801 ccgatttcta ccgcaatatg cgtattcagg atctggcaca agggatccat aagctgattc
    46861 gtaaacacga tcttcccggt ttgatgttgc gggcattcga tactttgccg gagatgatca
    46921 tgacgccaca tcaggcatgg caacgacaaa ttaaaggcga agtagaaacc attgcgctgg
    46981 aacaactggt cggtagagta tcggcaaata tgatcctgcc ttatccaccg ggcgtaccgc
    47041 tgttgatgcc tggagaaatg ctgaccaaag agagccgcac agtactcgat tttctactga
    47101 tgctttgttc cgtcgggcaa cattaccccg gttttgaaac ggatattcac ggcgcgaaac
    47161 aggacgaaga cggcgtttac cgcgtacgag tcctaaaaat ggcgggataa cttgccagag
    47221 cggcttccgg gcgagtaacg tgctgttaac aaataaagga gacgttatgc tgggtttaaa
    47281 acaggttcac catattgcga ttattgcgac ggattatgcg gtgagcaaag ctttctactg
    47341 cgatattctt ggtttcacgc tgcaaagcga agtctatcgc gaagcgcgcg actcatggaa
    47401 aggggatttg gcgcttaatg ggcaatatgt gattgagctt ttctcatttc cgttcccgcc
    47461 ggaacgaccc agccgaccgg aagcttgcgg tctgcgtcat ctggctttta gcgttgatga
    47521 catcgatgcg gcagtggcgc accttgaaag ccataacgtg aagtgtgaaa ccatccgtgt
    47581 cgatccatac acgcaaaaac gcttcacctt ctttaacgat ccggacgggc tgccgttgga
    47641 actgtatgag cagtaaggct tgtcatcgcc gcatttgccc ggtaacgtgc cgggcattgc
    47701 tactgtaaaa tcgcaccatc atgacactca cgctcaatag acaacttctc acctcacgcc
    47761 agattctggt ggcctttagc ggcgggcttg actccaccgt tctgctgcat cagttggtgc
    47821 agtggcggac ggaaaatccg ggtgtcgctc tgcgcgctat tcatgtgcat cacggtttaa
    47881 gtgccaatgc cgatgcctgg gttacgcatt gcgaaaacgt ctgccaacag tggcaggtgc
    47941 cgctggtggt cgaacgcgta caacttgcgc aagaaggact gggcattgag gcccaggcgc
    48001 ggcaggcacg ttatcaggca tttgcccgca ccttgttgcc cggtgaagtg ctggtcaccg
    48061 cgcaacatct cgacgatcaa tgtgaaacct ttctgctggc gctaaaacgc ggcagtggcc
    48121 ctgccgggct ttcggctatg gcggaagtct cggagtttgc cggaacgcgg cttattcgcc
    48181 cgttgctcgc ccgcacgcgg ggggaactgg tgcagtgggc gcgtcagtat gatttacgct
    48241 ggattgaaga cgaaagtaat caggacgact catacgatcg taactttctg cgcctgcgcg
    48301 tagtgccgtt attgcagcag cgttggccgc attttgccga agcaacggcc cgcagcgccg
    48361 cactttgtgc tgaacaagag agcctgctgg atgaactgct ggcagatgat ttagcacact
    48421 gtcaatcgcc gcaggggacg ctgcagattg tgccaatgct ggcgatgagt gatgcccgcc
    48481 gcgcggcgat tatccgccgc tggctggcag ggcagaatgc accgatgcct tcccgcgacg
    48541 cgttggtgag gatctggcag gaagtggcgc tggcgcggga agatgcctca ccctgtttac
    48601 gtttgggcgc gtttgaaatc cgacgctatc agtcgcaact gtggtggatt aaatccgtca
    48661 ccgggcaaag cgaaaacatt gtgccgtggc agacgtggct tcaaccgctg gaattaccgg
    48721 cggggctggg aagtgtacag cttaatgcgg gaggcgatat tcgccctccg cgtgcagacg
    48781 aagcggtcag cgtgcgtttc aaagcgccag gattgctgca tattgtcggg cgtaacggcg
    48841 gacgtaagct aaagaaaatc tggcaagagc tgggcgtgcc gccgtggcta cgtgacacca
    48901 cgccactgct gttttatggc gaaacgctga ttgcggcggc aggggtattt gtgacgcaag
    48961 aaggtgtggc tgaaggtgag aatggcgtaa gttttgtctg gcagaaaacg cttagttaag
    49021 tgaaagccgg ataagacgca tcaaacgtcg catccggcga aagtcaatca ggattcgctt
    49081 accaccaccg taccgatttc cgggtggcta aagctggtaa ttttatccag acgcagctcg
    49141 cgggtttcgc cagcggcctc gacgaccagg tactccacat ttttgcggga gactaaatca
    49201 ctggcttttg cctgcaattt ttcgccatct ttcagctcaa gtgtcagcat taaatgatgc
    49261 tggcaggcga gctcaagatt atcgtaatca tcacaattga ttggttgata cgtatcattc
    49321 attgacataa tcgctcacca gtaagtttgc cgcagcgtat gctgcttttt ccctgacagc
    49381 ctcagaaagg gcgtcgtcgg cagccatttc attcagcact ttcaaaacgc agcccagcgc
    49441 gtccggaacg tatcctaagt ctccgctggc gatttccgcg taccgcttgc gtattaactc
    49501 acaatatttt tccacatgcc ctcctgtcag cactctgact taaccgtgga tgcaagtcta
    49561 agcctacgaa gataaactct gtttcgcaag gtgactatac cacactcatt tctgcaatat
    49621 cagcgccgca actgcacgta ttccgttaca atggcctcct gattcgaaag gagttttctt
    49681 atggcgctta aagcgacaat ttataaagcg acggttaatg tggccgatct cgaccgcaac
    49741 cagtttctcg atgcctctct gacgctggcg cgccatcctt cagaaaccca ggagcgtatg
    49801 atgctgcgct tgctggcgtg gctgaaatat gctgatgaac gtctgcaatt tacccgtggt
    49861 ttgtgtgccg atgatgagcc ggaagcgtgg ctgcgtaacg atcacctggg cattgatttg
    49921 tggattgagc tggggctgcc ggatgagcgg cggattaaga aagcctgcac ccaggccgca
    49981 gaagtggcgc tgtttaccta taatagtcgg gcggcgcaaa tctggtggca gcaaaatcag
    50041 agcaaatgtg tgcagtttgc caatctttcc gtctggtatc tggacgatga acaactggcg
    50101 aaagtaagcg cctttgccga tcgtaccatg acgctgcagg caacgattca ggatggcgtg
    50161 atctggttat cggatgataa gaataatctg gaagtgaact taaccgcctg gcaacaacct
    50221 tcatgattgt gatttcccga catgttgcta ttcccgatgg tgagcttgag atcaccgcca
    50281 ttcgtgcgca gggcgcgggc gggcagcatg ttaataagac ctcaacggct attcatctgc
    50341 gttttgacat tcgggcgtcc agcctgccag agtattacaa agagcgtctg ctcgccgcca
    50401 gccatcattt gatcagcagt gatggcgtga ttgtcattaa ggcacaggaa taccgcagtc
    50461 aggaactgaa ccgcgaagca gctctggccc ggctggtggc tatgattaaa gaattaacaa
    50521 cagaaaaaaa agcccgacga cccacgcggc ccacccgtgc atcgaaagag cgcaggctgg
    50581 catcgaaagc acaaaaatca agcgtgaagg cgatgcgcgg caaagtgcgc agcggtcggg
    50641 aataaaaaga aggaatggat ggtgaaaaaa gcgatagtga cagcgatggc tgtaatcagc
    50701 ctctttactc tgatgggatg taataatcgg gccgaagtcg atacgctttc tccggcgcag
    50761 gctgccgaac tgaaaccgat gccgcaaagt tggcgcggcg tgctgccgtg tgccgattgc
    50821 gaaggaatcg aaacctctct gttcctcgaa aaagacggaa catgggtgat gaatgagcgt
    50881 tatctcggtg ctcgtgaaga accttcctcc ttcgcttcct acggtacatg ggcgcgaacc
    50941 gctgacaagc tggtattaac cgacagcaaa ggtgaaaagt catattatcg ggcgaaaggc
    51001 gatgcgctgg agatgctcga tcgtgaaggc aatccgattg aatcgcagtt caactatacg
    51061 ctggaagcgg cacaatccag tttacctatg acgccgatga ccctgcgggg catgtatttt
    51121 tatatggctg atgcggcgac cttcactgat tgcgcgaccg gaaaacgttt catggtagcg
    51181 aataacgcag agctggagcg tagctacctg gctgcgcgcg gtcacagtga aaaaccggtg
    51241 ttactgtcag tagaaggtca ctttacgctt gagggtaatc cggataccgg tgcgccgact
    51301 aaagtattgg cacccgatac ggcagggaaa ttttacccca accaggattg cagtagtttg
    51361 gggcagtaac ccgtcttgag acagaaacaa acgcaaaaca ggccagaagg atatatttca
    51421 acattttgaa tttgcacgtt ttttgtaggc cggataaggc gtttacgccg catccggcaa
    51481 tggtgctcaa cgcctgatgc gacgctggcg cgtcttatca tgcctacaac ccccctcata
    51541 ccttaaggcg gataaggcat ttactttatc accgggtcaa accaacaaag cgacccgcct
    51601 tgatataaat cccaggcttc aggtgcccaa catactgtaa ctgcgtttct ggcttaaacg
    51661 cagagacatc accaatacgc atatgcatca gatcggcagg gctaatccag cccgattgcg
    51721 ccagtgtaag tggatgcccg gctttggcaa aggcatccgt gacaaattcc gaacaaaacc
    51781 acgacttttt gtctccttcg cccacactgc ttaactgcgc tttcgccagg ccgctgacgc
    51841 actgttggcg aaaatcctcg gagaacggat tcagtgagca catctggcga gtcaccataa
    51901 agggaataaa ttcgacaatg ccgcgatagt tataaccgct atctttgatt ttattggcaa
    51961 acgcggtgat atctgtggct tgttgcgggg taagatccgg gactcgtaag acgaaaagct
    52021 tatcactatg cttcatcgct tttttaaggg aaacgatctg gacgccagcg cctgtcgctt
    52081 ctgcaacgtt attatcaccc agaaagattg caacgtgact cacagaggaa gtgctgaaga
    52141 cgcggattcc aaatgaggtt accccaaggc ttgaggagaa cagcaaatcg ccgggtttga
    52201 gatcaggtgc cgttatttct tttattgatt gttcggtgaa agagctttga tgctggaatt
    52261 tgacagccca tgtttttgcc tcggcatcta ctgctgtggc tgatgggtct ggctggctga
    52321 tatcaacggt acaagccgaa agtaaaagaa agctggggag aaacaggcgg cagtacgcct
    52381 ttggtttatc cattttatac aatccatgta aaaaaagggc cctgaaattc aggacccttt
    52441 ctggcatcag cctttaatct gtttcaccag atattcgacg atgtcaccag tcttaattaa
    52501 ctgtttctcg ccgttgcgac gatatttata ttcgatatcg tcgttgtcga ggttacggtc
    52561 gcccagcaca atagtgtgcg gaataccgat cagttccata tcagcaaaca tcacgcccgg
    52621 acgctctttg cggtcatcca gcagcacttc gataccttgt gcacgcagtt cgctgtacag
    52681 tttctcagca agctcttgta cgcggaagga tttgtgcatg ttcatcggca gaatcgccac
    52741 ctggaacggc gcgatagcgt caggccatac gatgcctcgt tcgtcgtagt tctgctcaat
    52801 cgccgcagct accacacgcg ttaccccgat accgtagcaa cccatcgtca ggatttggtt
    52861 acggccatct tcaccctgta cggaggcttt cagtgcttcg gagtacttgg tacccagctg
    52921 gaagatgtga ccaacttcga taccacgttt gatcagcagc gtaccctggc catccgggct
    52981 tggatcgcca gccaccacgt tacggatatc tgcaacttcc ggggtagcga catcgcgatc
    53041 ccagttgatg ccgaagtagt gtttaccatc gatgttagca ccagcagcga aatcactcat
    53101 cgccgcaacg gtacggtcaa tcaccaccgg aatcggcatg tttaccggac ccagtgaacc
    53161 cggaccggct ttaaccacgg cacgaatttc ttcttcggtc gcgaaagtca gcgggcttgc
    53221 aacctgcggc agtttttctg ctttaacttc gttcagctcg tgatcaccgc gcaccagcag
    53281 cgcaaccagc gggaagctgc tgccttcaac cgctttaacc agcagagtct taaccgtttt
    53341 ctcaatcggc agattgaact gttcaaccag ttccgcgatg gttttcgcgt tcggcgtatc
    53401 aaccagcgtc atttcctggg tagcagcagc gcgcggttct ttcggcgcga tagcttctgc
    53461 cagttcaatg ttcgctgcat agtcagaggt gtcggagaag accacatcgt cttcaccgct
    53521 ctgcgccagc acctggaatt cgtgagaggc gctgccgccg atagaaccgg tgtcggcttg
    53581 tacggcgcgg aaatccagcc ccatgcggct gaagattttg ctgtaggccg catacattgc
    53641 atcgtaggtt tcctgcaggg attcctgaga agtatggaaa gagtaagcat ctttcatcag
    53701 gaattcgcgg gaacgcatga cgccgaaacg cggacgcact tcgtcgcgga acttggtctg
    53761 gatctgatag aagttcagcg gcagctgttt gtaagagcta agctcgttac gaatcaggtc
    53821 agtgataact tcttcatgag ttgggccgag tacgaacgga cgctcgccac ggtcaacaaa
    53881 acgcagcagt tccggaccgt actgttccca acgaccactc tcttgccaca aatcggctgg
    53941 ctgaaccacc ggcatcgaca cctcgatcgc accggcgttg ttcatctctt cacgcacgat
    54001 gttttcgact tttttcagaa cgcgcacgcc ggtcggcagc caggtatata acccggaggc
    54061 cagcttgcgg atcatcccgg cgcgcagcat cagctgatgg ctgatcacct cggcgtcggc
    54121 aggtgtctcc ttgagagtgg agagcaggta ttggctagta cgcatgttgt tacggttcca
    54181 gttggaaggt agaacaggct caaggcgagc ctgggacaaa aaaaagtgat ttagtttacc
    54241 agtgcaaaag aaatgtcaaa agagaagggc gtgaatttaa cgcggttcca gcgcaaagac
    54301 ttcaaaacct gcgtcggtga cgcgccagcg aacgttaaaa tcatgtagcc agacggcata
    54361 ggttttgccc gtttcctcac ctttacgata ggccgggcgc gggtcctgcg ccagtacttc
    54421 gcggataaac agcgttaact gcggataacg cttctccagc gtcaaaagct gcttttcgac
    54481 ctctgcggta aaactcaccg ccatctctgc agctggcgca ctttgcgcat agctggcact
    54541 ggcatcggga agcgattcgg caaaggggag atacggtttg atatccacta ccggcgtacc
    54601 atcgaccaga tccagactgc cgagcttcag aatcacgctg tctttatggc aaacaacctc
    54661 tttcagctct accagcgaca tgccaattgg gttagggcgg aaagtagagc gtgttgcgaa
    54721 aacccccatt ctggcgttac cgccgaggcg cggtggacgc acagtcggac gccagccgcc
    54781 ttccatcgtt tgatgaaaga cgaaaaggat ccataaatgg ctgaacgctt ccaggccgcg
    54841 aacggcgtcg gcctggttgt agggagcaat gagatgcagt tcgccgttgg cgctttttac
    54901 cagacctggc tggcgcggaa cggcgaactt ttctttatag ggcgagcgaa taacgcctat
    54961 ttgctcgaac tggaaactgc tcatttcgcc gtaatgttaa gcgcagaacc gatacataca
    55021 gcctgacgat agcagcctgg cgtaccgctg gtgacttcgc agctatgcag taatacagca
    55081 ttggctttca ttttagaggc gttgatttgc atccgcttac gtgcggttgg aatgctcggc
    55141 ggagagtcct gattagaggc ctggcaagag tcgccactga cttcaccgag atcgcggaac
    55201 ggtttgccga ctaattcttc tgcattggta taaattcgga ccggcgtggc gcgcggcgct
    55261 ttcggttttg caggctccgc tttcggctgg ggtgcagtgc tttgaacggg ttcgacaggg
    55321 gatctgctta acatggaaca gccgcttagc atgagtgcta ctaaacagat cggtaaagca
    55381 cgcatagtat ttcctcaatg tatgatcaaa acgtcaatat tgaatcagga gcttgtaaaa
    55441 atgacaagac gggcaagcgc ccgtcctgaa tgatattaca aattgtggaa acagcctaaa
    55501 aattaccagc ctttaacagc tccgccgtta aacactttgt ttgctgcttc gtaaacttcg
    55561 tcagactgat aagcctggac gaatttcttc acgttctcgg cgtctttgtt atcttcacgc
    55621 gtcacgatca ggtttacgta cggggactct ttatcttcaa caaagatacc gtctttcgcc
    55681 ggagtcaggc caatctggct ggcataggtg gtattgataa ctgccagagc gatttgcgcg
    55741 tcgtccagag aacgcggcag ttgcggtgct tccagttcaa caattttcag atttttgggg
    55801 ttctcaacaa catcaagaac ggtcggcagc aggccaacgc catctttcag tttgatcaag
    55861 cccacttttt gcagcagcag cagtgaacga ccaaggttag ttgggtcgtt tggcacggca
    55921 acctgcgaac catcctgcag ttcatccagt gatttgattt tcttggagta accagcaatc
    55981 ggataaacaa aagtgttgcc tactgcgacc agtttgtagc cacgatcttt cagttgctga
    56041 tcaaggtacg gtttatgctg gaaggcgttg gcgtcgatat cgcctttgct caatgcttcg
    56101 tttggcagaa catagtcgtt gaaggttacc agctcaacgt ccaggccata tttgtctttc
    56161 gcaactttct gcgcgacttc tgcaacctgc tgttcggcac caacaatcac gccgacttta
    56221 atgtggtttg gatctttttc atcctgaccg cagcctacca gtgccagtga tccgatcagg
    56281 gctcccactg ccgcaaaggt tttgaatttg aacgccatac cttattcctt cttcaattat
    56341 ttatgttgtg ttgaacgtta cttgcgagtg acagcccgga cgatgcggtc gcctgcgaac
    56401 tgaattaaat aaaccagaat gaccagcaat accagtaccg tattcatcac cgtcgcgtta
    56461 tagccgatgt agccatactg atagccaatc tgacctaaac caccggcacc gactgcacca
    56521 cccatcgcgg aataaccgac cagggtaatc agggtgatag ttgccgcatt caccagaccc
    56581 ggcagcgctt ccggtaacag caccttacgg acgatctgca tcggcgtggc acccattgcg
    56641 cgggaagctt caattaaccc ggttgggatc tccagcagag cgttctcgac catacgggca
    56701 ataaacggtg ctgcaccaac ggttaacgga acaatcgctg cctgcaaacc aatcgatgta
    56761 ccgacaataa cgcgggtaaa cggaatcatc catacaagca agataatgaa cgggatggaa
    56821 cggaaaatgt tcacaatcgc agaaacggta cgatacagct tcgcgttagc aataatttgc
    56881 cccggacgcg tgacataaag cagaacgcca accggcagac caatcacaaa gccaaaaaaa
    56941 ccggatacga aggtcattgc cagcgtttcc catacgccac gaaccagcag ccacatcatc
    57001 ggctcagaca taacccagta cctctacttt tacatggtgt tcctgcagcc aggcaatggc
    57061 ggcttgcgta tcttgttgtg tgccgtgcat ttcagtcagc atgatgccga acttaacgcc
    57121 accggcgtaa tccatctgcg cgctaataat gttgttgttg acgttgaaac gacgcgcggt
    57181 ttcagaaagc agtggggcat cgaccgattg accggtaaac tccagacgca gcatcggcac
    57241 gcagtcagta aatggctccg cttgcagacg ttcctggtaa tcttccggga tatccagatg
    57301 cagggtcgac tgaataaact tctgcgccag cggcgttttc ggatgcgaga acacttcact
    57361 taccgtgtcc tgctcgatca gttctccatt gctgatgacc gccacgcaat cacaaatgcg
    57421 cttcacaacg tccatttcgt gggtgatcaa cagaatcgtc aaccccagac ggcggttgat
    57481 gtctttcagc agttcgagaa tagaacgtgt cgttgccggg tccagcgcgc tggtggcttc
    57541 atcacacagc aatactttgg gattgctggc taacgcacgg gcaattgcca cacgttgttt
    57601 ctgcccaccg gaaagattcg acgggtagct atcatgctta tcgccaagac caaccaatga
    57661 cagcaattcc gtcacgcgac gtttgacctc gtctttcggt gtgttgtcca gctccagcgg
    57721 cagagccacg ttgccaaaaa cagtacgcga agagagcagg ttaaaatgct ggaaaatcat
    57781 accaatctgg cggcgagctt tggtcaactc ggattctgac agcgtggtca gttcctggcc
    57841 atcgaccagc acgctaccct cggttgggcg ctccagcagg tttacacaac gtataagcgt
    57901 actcttaccc gcgcctgagg caccgataac gccataaatt tgtccagctg gcacatgcag
    57961 gctgacgttg ttcaacgcct ggatggtgcg ggtgccctgg tggaacactt tggtgatatt
    58021 cgaaagtttt atcattgatt atttattatc gtcattaagt tagtcgtggc atctcgaatg
    58081 cctgaaacgg gcaacgccgt caatgaaatg gatgttaagg catccagacg tctaaatcaa
    58141 tcaggtttat gcgaagagca ctttcttgca ggtcgaaaca tgcgatacta gcgtcacatg
    58201 ccttattaag gagctataaa aggtggcgaa gagcgtaccc gcaatttttc ttgaccgtga
    58261 tggcaccatt aatgtcgatc acggctatgt ccatgagatc gacaactttg aatttatcga
    58321 cggtgttatt gacgccatgc gcgagctaaa aaaaatgggc tttgcgctgg tggtagtaac
    58381 caaccagtct ggcattgctc gcggtaaatt taccgaagca cagtttgaaa cgctgaccga
    58441 gtggatggac tggtcgctgg cggaccgaga tgtcgatctg gatggtatct attattgccc
    58501 gcatcatccg cagggtagtg ttgaagagtt tcgccaggtc tgcgattgcc gcaaaccaca
    58561 tccggggatg cttttgtcag cacgcgatta tttgcatatt gatatggccg cttcttatat
    58621 ggtgggcgat aaattagaag atatgcaggc agcggttgcg gcgaacgtgg gaacaaaagt
    58681 gctggtgcgt acgggtaaac ctattacgcc tgaagcagaa aacgcggcgg attgggtgtt
    58741 aaatagcctg gcagacctgc cgcaagcgat aaaaaagcag caaaaaccgg cacaatgatt
    58801 aaaagatgag cggttgaaat aaaaatgcat ttttccgctt gtcttcctga gccgactccc
    58861 tataatgcgc ctccatcgac acggcggatg tgaatcactt cacacaaaca gccggttcgg
    58921 ttgaagagaa aaatcctgaa attcagggtt gactctgaaa gaggaaagcg taata
//
LOCUS       DAPHKZ010000015        55598 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.015, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000015 DAPHKZ010000000
VERSION     DAPHKZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 55598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55598
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.015"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..2756
                     /locus_tag="RH288_000985"
     CDS             <1..2756
                     /locus_tag="RH288_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001413112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HDV4030074.1"
                     /translation="TGQAFYNDGTGTIVNYGTICTFGVCQSGNEYNNTDDFTSLIYTG
                     GDTITRSGETVTLNKSAAVTDKLAGNVVNSGTLSGDQITVSSGLLENTSGGIINNLVK
                     LDKGAVIKNAGVMTNNVDVSGGILNNAGEMTAQITMNAGADSSLVNNTGTINKIVQNA
                     GVFNNSGSVTGRMMSAGGVFNNQTDGAIMRGAALTGTAVANNEGTWNLGSSSEGNNTG
                     MLEVNNNSAFNNRGEFILDNDKNAVHINQSGTLYNTGHMNISNSSHNGAVNMWGGNGR
                     FINDGTIDVSAKSLVVSANNAGDQNAFFWNQDNGVINFDHDSASAVKVTHSNFIAQND
                     GIMNISGTGAVAMEGDKNAQLVNNGTINLGTAGTTDTGMIGMQLDANATADAVIENNG
                     TINIFANDSFAFSVLGTVGHVVNNGTVVIADGVTGSGLIKQGDSINVEGMNGNNGNSS
                     EVHYGDYTLPDVPKPNTVSVTSGSDEAGGSMNNLNGYVVGTNVNGSAGKLKVNNASMN
                     GVEINTGFTAGTADTTVSFDNVVEGSNLTDADAITSTSVVWTAKGSTDASGNVDVTMS
                     KNAYTDVATDASVNDIAKALDAGYTNNELFTSLNVGTTAELNSALKQVSGSQATTVFR
                     EARVLSNRFSMLADAAPKVGNGLAFNVVAKGDPRAELGNNTEYDMLALRKTIDLSESQ
                     TMSLEYGIARLDGDGAQKAGDNGVTGGYSQFFGLKHQMSFDNGMNWNNALRYDVHNLD
                     SSRSIAFGNTNKTADTDVKQQYLEFRSEGAKTFEPSEGLKVTPYAGVKLRHTLEGGYQ
                     ERNAGDFNLNMNSGSETAVDSIVGLKLDYAGKDGWSASATLEGGPNLSYAKSQRTASL
                     AGAGSQHFNVDDGQKGGGINSLTSVGVKYSSKESSLNLDAYNWKEDGISDKGVMLNFK
                     KTF"
     gene            2964..3824
                     /gene="pdxI"
                     /locus_tag="RH288_000986"
     CDS             2964..3824
                     /gene="pdxI"
                     /locus_tag="RH288_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 4-dehydrogenase"
                     /protein_id="HDV4030075.1"
                     /translation="MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLRE
                     ALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPA
                     ELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIG
                     LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPL
                     QSSTLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEV
                     LSTLDGISRE"
     gene            3887..6193
                     /locus_tag="RH288_000987"
     CDS             3887..6193
                     /locus_tag="RH288_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing bactofilin"
                     /protein_id="HDV4030076.1"
                     /translation="MFKARNCGWIRLLPLFMLSLPVQAELRCVANAVDIESFFSAATA
                     EDKQQVEQAINSSVNLVPFGLSASNWKVHRGDLVVEGNIESNQKLIVLGNLTVKGNIS
                     TFSLSNPWVILGNVTATNIVADSPLLITGSINASGLVFIDSYYDNPSTIKGSINARGI
                     FINDIIAPVVASSTNSEFMVRASDKHDTENVKKALMIINPDAYYWGLINDEDALKEIF
                     KRSNIRMAGNVCNQMKKEALFRPKPSPELVQELQMLDEGKVAAFEGRDIATFDLAVMR
                     TLPRLKGISANLRKQLINSNDEQTIESMARYMPDNEILELTDQQLGYQPVVLGLLDRE
                     PLSVEIMTRMSRLPDGVGPLNLALRENLPLDIVMTLAKRDWDMIIQELYKDAWLLPES
                     IIDGYIRSDDSSIRQVGAGGQLTYNQAMQLANDSSNNVVTSLAFKLAEMKHHGQLLRM
                     TPQESDKVAGYLYQKFENDDDLIRVLFLALPDNLQFNFVKRMEKKSPAYFCCRDMQVI
                     HSDAALQRLLTRFNDPEGWSNLAKNQYLSTSMKQKIWQRALSHRKNNPKADSDAYETS
                     ADMILSELISHGEVDDQMLLNATALIRSDDWDFLESALISWDNLPAVVLKELQQNTPR
                     NDIWAKFFLRQENSSRAQVDEALRVYYALDPDALAQLDVLAKQPDRIWWSTLAKSNLT
                     FFKFGALNNRHTPPAVLAAEIDPEWWIVAMNNPRFPVDVLKARLKRDPLLALELVNPE
                     LDLVRQLALNGKTRAIREQAMRKLDELY"
     gene            6364..6963
                     /locus_tag="RH288_000988"
     CDS             6364..6963
                     /locus_tag="RH288_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415926.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDV4030077.1"
                     /translation="MTLYQIKPLFQSLLRPTMFWLYKHHVTANHITLAALALSLLTGL
                     LLMLAAILFLLLPIVLFIRMALNALDGMLARECNQQTRLGAILNETGDVISDIALYLP
                     FLFLPESNASLVILMLFCTILTEFCGLLAQTINGVRSYAGPFGKSDRALIFGLWGLAV
                     AIYPQWMQWNNLLWSIASILLLWTAINRCRSVLLMSAEI"
     gene            6963..7859
                     /locus_tag="RH288_000989"
     CDS             6963..7859
                     /locus_tag="RH288_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDV4030078.1"
                     /translation="MLEKSLATLFALLILATLINRFLLWRLPERKGGEVTLRIRTWWG
                     IVICFSMVISGPRWMTLTFFALISFLALKEYCTLISVHFPRWLYWGIPLNYLLIGFNC
                     FELFLLFIPLAGFLILATGQVLVDDPSGFLHTVSAIFWGWIMTVFALSHAAWLLMLPT
                     TNIQGGALLVLFLLALIESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLMGGVITIMI
                     ASLIIGPLLTPLNTLQALLAGLLIGISGFCGDVVMSAIKRDIGVKDSGKLLPGHGGLL
                     DRIDSLIFTAPVFFYFIRYCCY"
     gene            7875..9632
                     /locus_tag="RH288_000990"
     CDS             7875..9632
                     /locus_tag="RH288_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional alpha/beta hydrolase/class I
                     SAM-dependent methyltransferase"
                     /protein_id="HDV4030079.1"
                     /translation="MENSRIPGEHFFTTSDNTALFYRHWPALQPGAKKVIVLFHRGHE
                     HSGRLQHLVDELAMPDTAFYAWDARGHGKSSGPRGYSPSLARSVRDVDEFVRFAASDS
                     QVGLEEVVVIAQSVGAVLVATWIHDYAPAIRGLVLASPAFKVKLYVPLARPALALWHR
                     LRGLFFINSYVKGRYLTHDRQRGASFNNDPLITRAIAVNILLDLYKTSERIIRDAAAI
                     TLPTQLLISGDDYVVHRQPQIDFYQRLRSPLKELHLLPGFYHDTLGEENRALAFEKMQ
                     SFISRLYANKSQKFDYQHEDCTGPSADRWRLLSGGPVPLSPVDLAYRFMRKAMKLFGT
                     HSSGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLVDKIYLNSVGWRGIRQRKTHLQ
                     ILIKQAVADLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQE
                     MIAQRGMSGRVRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPENEQVKNSLAGLAN
                     AIEPGGILIYTGQPWHPQLEMIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDAGFDKCT
                     QRIDEWGIFTVSMAVRRDN"
     gene            9622..10938
                     /locus_tag="RH288_000991"
     CDS             9622..10938
                     /locus_tag="RH288_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2/dual specificity phosphatase
                     family protein"
                     /protein_id="HDV4030080.1"
                     /translation="MITERRNVLLQGAGWLLLLAPFFFFTYGSLNQFTAVQDLNSHDI
                     PSQVFGWETAIPFLPWTIVPYWSLDLLYGFSLFVCSTTFEQRRLVHRLILATVMACCG
                     FLLYPLKFSFIRPEVSGVTGWLFSQLELFDLPYNQSPSLHIILCWLLWRHFRQHLAER
                     WRKVCGGWFLLIAISTLTTWQHHFIDVITGLAVGMLIDWMVPVDRRWNYQKPDQRRIK
                     IALPYVVGAGSCIVLMELMMMIQLWWSVWLCWPVLSLLIIGRGYGGLGAITTGKDSQG
                     KLPPAVYWLTLPCRIGMWLSMRWFCRRLEPVSKMTAGVYLGAFPRHIPAQNAVLDVTF
                     EFPRGRATKDRLYFCVPMLDLVVPEEGELRQAVAMLETLREEQGSVLVHCALGLSRSA
                     LVVAAWLLCYGHCKTVNEAISYIRARRPQIVLTDEHKAMLRLWENR"
     gene            complement(10992..11597)
                     /gene="azoR"
                     /locus_tag="RH288_000992"
     CDS             complement(10992..11597)
                     /gene="azoR"
                     /locus_tag="RH288_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDV4030081.1"
                     /translation="MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLA
                     ANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNIS
                     TQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
                     LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVSA"
     gene            11798..15700
                     /gene="hrpA"
                     /locus_tag="RH288_000993"
     CDS             11798..15700
                     /gene="hrpA"
                     /locus_tag="RH288_000993"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415931.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HDV4030082.1"
                     /translation="MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQ
                     AIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
                     SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELSQESHGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHI
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGR
                     IAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEF
                     YDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVKPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKIT
                     FRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCISCGVDKLIDANGGPVWTEEGFAALHEKVRAELN
                     DTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWVNKLPPARREDEDVK
                     EIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG"
     gene            15972..16772
                     /locus_tag="RH288_000994"
     CDS             15972..16772
                     /locus_tag="RH288_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDV4030083.1"
                     /translation="MNITPFPTLSPATIDAINVIGQWLAQDDFSGEVPYQADCVILAG
                     NAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYSAIAQHPHYNTIRTTGRAEATIL
                     ADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLNQAVERVHTAIVVQDPTMQRRTM
                     ATFRRMTGDNPDAPRWLSYPGFVPQLGNNADSVIFINQLQGLWPVERYLSLLTGELPR
                     LRDDSDGYGPRGRDFIVHVDFPAEVIHAWQTLKHDAVLIEAMESRSLR"
     gene            16969..18408
                     /gene="aldA"
                     /locus_tag="RH288_000995"
     CDS             16969..18408
                     /gene="aldA"
                     /locus_tag="RH288_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDV4030084.1"
                     /translation="MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAE
                     DARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAE
                     VEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
                     RKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAG
                     NPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDS
                     RVINSGQVCNCAERVYVQKGIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAAL
                     ERVEQKVARAVEEGARVAFGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVV
                     AFDTLEDAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHA
                     GWRKSGIGGADGKHGLHEYLQTQVVYLQS"
     gene            complement(18450..19450)
                     /gene="gap"
                     /locus_tag="RH288_000996"
                     /pseudo
     CDS             complement(18450..19450)
                     /gene="gap"
                     /locus_tag="RH288_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310049.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
     gene            19639..20169
                     /gene="cybB"
                     /locus_tag="RH288_000997"
     CDS             19639..20169
                     /gene="cybB"
                     /locus_tag="RH288_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
                     /protein_id="HDV4030085.1"
                     /translation="MENKYSRLQISIHWLVFLLVIAAYCAMEFRGFFPRSDRPLINMI
                     HVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGL
                     VMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHY
                     FWKDNTLLRMMPRKRS"
     gene            20414..20587
                     /locus_tag="RH288_000998"
     CDS             20414..20587
                     /locus_tag="RH288_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030086.1"
                     /translation="MKKLALILFMGTLVSFYADAGRKPCSGSKGGISHCTAGGKFVCN
                     DGSISASKKTCTN"
     gene            complement(20659..20808)
                     /gene="hokB"
                     /locus_tag="RH288_000999"
     CDS             complement(20659..20808)
                     /gene="hokB"
                     /locus_tag="RH288_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokB"
                     /protein_id="HDV4030087.1"
                     /translation="MKHNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALM
                     ACTSR"
     gene            21207..22847
                     /gene="trg"
                     /locus_tag="RH288_001000"
     CDS             21207..22847
                     /gene="trg"
                     /locus_tag="RH288_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein Trg"
                     /protein_id="HDV4030088.1"
                     /translation="MNTTPSQRLGFLHHIRLVPLFACILGGILVLFALSSALAGYFLW
                     QADRDQRDVTAEIEIRTGLANSSDFLRSARINMIQAGAASRIAEMEAMKRNIAQAESE
                     IKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAIINHE
                     SEQIRPLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLIT
                     FMVLRRIVIRPLQHAAQRIEKIASGDLTMNDEPAGRNEIGRLSRHLQQMQHSLGMTVG
                     TVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAASMEQLTATVKQNADNAHHA
                     SKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAV
                     EAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTM
                     STIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNASLVEEASAAAVS
                     LEEQAARLTEAVDVFRLHKHSVSAEPRGAGEPVSFATV"
     gene            complement(22885..23808)
                     /locus_tag="RH288_001001"
     CDS             complement(22885..23808)
                     /locus_tag="RH288_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415939.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4030089.1"
                     /translation="MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSK
                     TLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGRSLHRKEGLNNDV
                     VRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
                     PELMTGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDAL
                     VQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGA
                     GEPIGILTRVDATFSSGCQLMINAIRKSMPF"
     gene            24025..25368
                     /locus_tag="RH288_001002"
     CDS             24025..25368
                     /locus_tag="RH288_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDV4030090.1"
                     /translation="MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVL
                     ENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQA
                     GVPVHSTAFRPIDDASLARNPFRVFTSLLRLELIENEILRQKAAEILRQRDIFTPRCR
                     QLLEEYEQQGGFNETQAQEFVQEALETFRWHQSATVDEETYRALHNEHRLIADVVCFP
                     GCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLF
                     AGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFP
                     DSEFLMRQQGLAWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVVAQPITYEDFLPVS
                     AAGIFQSNLGNETQTRSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL"
     gene            25593..27248
                     /gene="opgD"
                     /locus_tag="RH288_001003"
                     /gene_synonym="mdoD"
     CDS             25593..27248
                     /gene="opgD"
                     /locus_tag="RH288_001003"
                     /gene_synonym="mdoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415941.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein OpgD"
                     /protein_id="HDV4030091.1"
                     /translation="MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQR
                     FDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLD
                     AQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFW
                     FDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNP
                     KGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVC
                     FWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFSEGWAPGEHYPEK
                     WARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSD
                     STDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS"
     gene            27388..27612
                     /locus_tag="RH288_001004"
     CDS             27388..27612
                     /locus_tag="RH288_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415943.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HDV4030092.1"
                     /translation="MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGY
                     NAEVVRMKKQKLQLKDEMLKILQQESVKEV"
     gene            27675..28214
                     /gene="rimL"
                     /locus_tag="RH288_001005"
     CDS             27675..28214
                     /gene="rimL"
                     /locus_tag="RH288_001005"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HDV4030093.1"
                     /translation="MTETIKVSESLELHAVAENHVKPLYQLICKNKTWLQQSLNWPQF
                     VQSEEDTRKTVQGNVMLHQRGYAKMFMIFKEDELIGVISFNRIEPLNKTAEIGYWLDE
                     SHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPQSNQVALRNGFILEGCLKQAE
                     FLNDAYDDVNLYARIIDSQ"
     gene            complement(28206..29186)
                     /locus_tag="RH288_001006"
     CDS             complement(28206..29186)
                     /locus_tag="RH288_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030094.1"
                     /translation="MRKYRLSEEQRAFSYQEDGTKKNVLLRQIIAISDFNDVIAGTAG
                     GWIDRETVLAQEGNCWIYDQNAIAFGGAVISGNTRITGTSVLWGEVYATDNVWIDNSE
                     ISQGAYISDSVTIHDSLVYGQCRIFGHALIDQHSMIVAAQGLTPDHQLLLQIYDRARV
                     SASRIVHQAQIYGDAVVRYAFIEHRAEVFDFASIEGNEENNVWLCDCAKVYGHAQVKA
                     GIEEDAIPTIHYSSQVAEYAIVEGNCVLKHHVLVGGNAVVRGGPILLDEHVVIQGESR
                     ITGAVIIENHVELTDHAVVEAFDGDTVHVRGPKVINGEERITRTPLAGLL"
     gene            29310..30302
                     /gene="tehA"
                     /locus_tag="RH288_001007"
     CDS             29310..30302
                     /gene="tehA"
                     /locus_tag="RH288_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HDV4030095.1"
                     /translation="MQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGL
                     VILAMIIWGLLTSAFIARLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFR
                     PLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG
                     YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSV
                     NGGEGDTLAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGS
                     GSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLVRTERAVLMKAEDKE"
     gene            30299..30892
                     /gene="tehB"
                     /locus_tag="RH288_001008"
     CDS             30299..30892
                     /gene="tehB"
                     /locus_tag="RH288_001008"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HDV4030096.1"
                     /translation="MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRN
                     SLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILST
                     VVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
                     EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK"
     gene            31194..31862
                     /locus_tag="RH288_001009"
     CDS             31194..31862
                     /locus_tag="RH288_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HDV4030097.1"
                     /translation="MRTTSFAKVAALCGLLALSGCASKITQPDKYSGFLNNYSDLKET
                     TSATGKPVLRWVDPSFDQSKYDSIVWNPITYYPVPKPSTQVGQKVLDKILNYTNTEMK
                     EAIAQRKPLVTTAGPRSLIFRGAITGVDTSKEGLQFYEVVPVALVVAGTQMATGHRTM
                     DTRLYFEGELIDAATNKPVIKVVRQGEGKDLNNESTPMAFENIKQVIDDMATDATMFD
                     VNKK"
     gene            complement(31880..32386)
                     /gene="tnpA"
                     /locus_tag="RH288_001010"
                     /pseudo
     CDS             complement(31880..32386)
                     /gene="tnpA"
                     /locus_tag="RH288_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604919.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            32394..33602
                     /locus_tag="RH288_001011"
     CDS             32394..33602
                     /locus_tag="RH288_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV4030098.1"
                     /translation="MKRLQAFKFQLRPGGQQECEMRRFAGACRFVFNRALARQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDLERAYKNFFRKRAAFPR
                     FKKRGQNDAFRYPQGVKLDQENSRIFLPKLGWMRYRNSRQVTGVVKNVTVSQSCGKWY
                     ISIQTESEVSTPVHPSASMVGLDAGVAKLATLSDGTVFEPVNSFQKNQKKLARLQRQL
                     SRKVKFSNNWQKQKRKIQRLHSCIANIRRDYLHKVTTAVSKNHAMIVIEDLKVSNMSK
                     SAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLAYKQLWRGGQVLAVPPAYTSQRC
                     AYCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAVLACGEMVQSGRPLKQ
                     EPTEMIQATA"
     gene            complement(33642..34856)
                     /gene="ydcO"
                     /locus_tag="RH288_001012"
     CDS             complement(33642..34856)
                     /gene="ydcO"
                     /locus_tag="RH288_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BenE family transporter YdcO"
                     /protein_id="HDV4030099.1"
                     /translation="MLRCLYAITHEVTMRLFSIPPPTLLAGFLAVLIGYASSAAIIWQ
                     AAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQGLT
                     LNEAIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQ
                     FTLCGSMLLVWLATKAVAPRYAVIAAMIIGIVIVIAQGDVVTTDVVFKPVLPTYITPD
                     FSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSAPVSPLIVFTGLLALVFSPFGVY
                     SVGIAAITAAICQSPEAHPDKDQRWLAAAVAGIFYLLAGLFGSAITGMMAALPVSWIQ
                     MLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLVGIGSAFWGLIAGGVCY
                     VVLNLIADRNRY"
     gene            34909..35445
                     /gene="sutR"
                     /locus_tag="RH288_001013"
     CDS             34909..35445
                     /gene="sutR"
                     /locus_tag="RH288_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SutR"
                     /protein_id="HDV4030100.1"
                     /translation="MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSTFISPPQSATPSVYDPQQQAMVITSLFPYDPQLCFEHF
                     SIQMASGAISESTPHEKGVIEHVVVIDGQLDLCVDGEWQTLNCGEGVRFAADVTHIYR
                     NGGEQTVHFHSLIHYPRS"
     gene            35518..37479
                     /gene="rlhA"
                     /locus_tag="RH288_001014"
     CDS             35518..37479
                     /gene="rlhA"
                     /locus_tag="RH288_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA 5-hydroxycytidine C2501 synthase"
                     /protein_id="HDV4030101.1"
                     /translation="MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLDQIRAIHQATDATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLARAS
                     SGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVVKVAKDHLDV
                     AVTEPLANGDGLNVLIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRPHHPLNR
                     NLDHNWQQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSITHTLDGQFDEANNA
                     EKAMNNLKDGLAKLGQTLYYARDVQINLPGALFVPNSLLNQFRREAADMLDAARLASY
                     QRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPLPGSVVASVSPDELLKTLPKRKG"
     gene            complement(37571..37801)
                     /locus_tag="RH288_001015"
     CDS             complement(37571..37801)
                     /locus_tag="RH288_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncJ family protein"
                     /protein_id="HDV4030102.1"
                     /translation="MFTKALSVVLLTCALFSGQLMAGHKGHEFVWVKNVDHQLRHEAD
                     SDELRAVAEESAEGLREHFYWQKSRKPEAGQR"
     gene            38023..38199
                     /gene="hicA"
                     /locus_tag="RH288_001016"
     CDS             38023..38199
                     /gene="hicA"
                     /locus_tag="RH288_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin HicA"
                     /protein_id="HDV4030103.1"
                     /translation="MKQSEFRRWLESQGVDVANGSNHLKLRFHGRRSVMPRHPCDEIK
                     EPLRKAILKQLGLS"
     gene            38245..38661
                     /gene="hicB"
                     /locus_tag="RH288_001017"
     CDS             38245..38661
                     /gene="hicB"
                     /locus_tag="RH288_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HicB"
                     /protein_id="HDV4030104.1"
                     /translation="MRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALL
                     TAFDFYFEDNELIPLPSPLNSHDHFIEVPLSVASKVLLLNAFLQSEITQQELARRIGK
                     PKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV"
     gene            38740..40146
                     /locus_tag="RH288_001018"
     CDS             38740..40146
                     /locus_tag="RH288_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDV4030105.1"
                     /translation="MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVS
                     HAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRD
                     PSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
                     QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSV
                     ATDVKEGIDLQALELALQEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTL
                     IEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKI
                     HHNDSGYFLWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWG
                     EREEQAVKQLGKLIQERL"
     gene            40391..41536
                     /locus_tag="RH288_001019"
     CDS             40391..41536
                     /locus_tag="RH288_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV4030106.1"
                     /translation="MSKTFARSSLCALSMTIMTAHAAEPPTNLDKPEGRLDIIAWPGY
                     IERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMTKGGYDLVTASGDASLRLI
                     MGKRVQPINTALIPNWKTLDPRVVKGDWFNVGGKVYGTPYQWGPNLLMYNTKTFPTPP
                     DSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQY
                     QAVLKVLRAQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFP
                     KEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPEGCKASPL
                     LGEKGCETNGFNYFDKIAFWKTPIAEGGKFVPYSRWTQDYIAIMGGR"
     gene            41554..42567
                     /locus_tag="RH288_001020"
     CDS             41554..42567
                     /locus_tag="RH288_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4030107.1"
                     /translation="MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKT
                     TCLRLIAGFEQLSGGAISIFGKPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLM
                     VKGVNKKQRHAMAQEALEKVALGFVHQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
                     PLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDS
                     PRDLYMRPRTPFVAGFVGTSNVFDGLMAEKLCGMTGSFALRPEHIRLNTPGELQANGT
                     IQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQVMVSWSRDVMVPLV
                     EER"
     gene            42568..43509
                     /locus_tag="RH288_001021"
     CDS             42568..43509
                     /locus_tag="RH288_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4030108.1"
                     /translation="MAMNVLQSPSRPGLGKVSGFFWHNPGLGLFLLLLGPLMWFGIVY
                     FGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFNPANYDIILRTLTMAVAVTIASA
                     ILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHL
                     GLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQAS
                     ADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQ
                     QGAIGNMPMAAAFTLVPIILIALYLAFVKRLGAFDAL"
     gene            43499..44293
                     /locus_tag="RH288_001022"
     CDS             43499..44293
                     /locus_tag="RH288_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4030109.1"
                     /translation="MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPP
                     QGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAIS
                     LLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
                     WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTL
                     PLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILGAWWLTREGDNGQ"
     gene            44315..45739
                     /gene="patD"
                     /locus_tag="RH288_001023"
     CDS             44315..45739
                     /gene="patD"
                     /locus_tag="RH288_001023"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HDV4030110.1"
                     /translation="MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAA
                     VRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIP
                     AIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
                     PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINILFGRGKTVGDPLTGHPKVR
                     MVSLTGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNA
                     GQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVSKA
                     VEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNE
                     EQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLS
                     GYGKDMSLYGLEDYTVVRHVMVKH"
     gene            complement(45836..45931)
                     /gene="yncL"
                     /locus_tag="RH288_001024"
     CDS             complement(45836..45931)
                     /gene="yncL"
                     /locus_tag="RH288_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HDV4030111.1"
                     /translation="MNVSSRTVVLINFFAAVGLFTLISMRFGWFI"
     gene            46126..46299
                     /gene="ortT"
                     /locus_tag="RH288_001025"
     CDS             46126..46299
                     /gene="ortT"
                     /locus_tag="RH288_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orphan toxin OrtT"
                     /protein_id="HDV4030112.1"
                     /translation="MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATW
                     PMSFPVALLFSLF"
     gene            46385..46618
                     /locus_tag="RH288_001026"
     CDS             46385..46618
                     /locus_tag="RH288_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcY family protein"
                     /protein_id="HDV4030113.1"
                     /translation="MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTQ
                     QQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL"
     gene            complement(46619..47068)
                     /locus_tag="RH288_001027"
     CDS             complement(46619..47068)
                     /locus_tag="RH288_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV4030114.1"
                     /translation="MNQSLTLAFLIAAGIGLVVQNTLMVRITQTSSTILIAMLLNSLV
                     GIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLMLDIFRSHGVPLRALFGPICGAILLVVGAWLVARRSF"
     gene            complement(47065..47583)
                     /gene="mddA"
                     /locus_tag="RH288_001028"
     CDS             complement(47065..47583)
                     /gene="mddA"
                     /locus_tag="RH288_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HDV4030115.1"
                     /translation="MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFE
                     ARTLAGYPVLVSEENGVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLS
                     RLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVVTAQMPQVGTKFGRWLDLTFMQL
                     QLDERTEPDAIG"
     gene            47764..48801
                     /gene="curA"
                     /locus_tag="RH288_001029"
     CDS             47764..48801
                     /gene="curA"
                     /locus_tag="RH288_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415966.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent curcumin/dihydrocurcumin
                     reductase"
                     /protein_id="HDV4030116.1"
                     /translation="MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLR
                     TVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVSRVVESNHPDYQSGDWVLGYSGW
                     QDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
                     PVGATVGQIGKLKGCRVVGVAGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKG
                     IDIYYENVGGKVFDAVLPLLNTSARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKR
                     IRLQGFIIAQDYGHRIHEFQREMGQWVKEDKIHYREEITDGLENAPQTFIGLLKGKNF
                     GKVVIRVAGDD"
     gene            48999..49664
                     /gene="mcbR"
                     /locus_tag="RH288_001030"
     CDS             48999..49664
                     /gene="mcbR"
                     /locus_tag="RH288_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415967.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid/biofilm transcriptional regulator
                     McbR"
                     /protein_id="HDV4030117.1"
                     /translation="MPGTGKMKHVSLTLQVENDLKHQLSIGALKPGARLITKNLAEQL
                     GMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKRQLDEINRIRYELELMAVALAVE
                     NLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPILCEMIEQLWV
                     RMGPGLHYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEIMQQNIAILYQQ
                     YNR"
     gene            complement(49700..51802)
                     /locus_tag="RH288_001031"
     CDS             complement(49700..51802)
                     /locus_tag="RH288_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HDV4030118.1"
                     /translation="MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTP
                     AAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIR
                     GIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQ
                     QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQK
                     NLANAKLGVRIDEASKLSLIFNSVDIKADDPGGLTKAEWKANPQQAPRAEQYDTRKTI
                     KQTQAGLRYERSLSSRDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQ
                     GIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNSGMPEYGQKGELRRDERN
                     LMWNIDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPA
                     GSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNLGLKPSTNDTIEIGSKTR
                     IGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVNA
                     SWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGTEARYMGDIMA
                     DDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYE
                     PSPGRNYGVGMNIAWRFE"
     gene            52044..53105
                     /locus_tag="RH288_001032"
     CDS             52044..53105
                     /locus_tag="RH288_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDV4030119.1"
                     /translation="MHLRHLFSSRLRGSLLLGSLLVVSSFSTQAAEEMLRKAVGKGAY
                     EMAYSQQENALWLATSQSRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQT
                     LWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDATNTVYISGI
                     GKESVIWVVDGGNIKLKTAIQNTGKMSTGLALDSEGKRLYTTNADGELITIDTADNKI
                     LSRKKLLDDGKEHFFINISLDTARQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLA
                     VLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQ
                     KSTKQQEATQPDDVIRIAL"
     gene            complement(53218..54717)
                     /gene="ansP"
                     /locus_tag="RH288_001033"
     CDS             complement(53218..54717)
                     /gene="ansP"
                     /locus_tag="RH288_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HDV4030120.1"
                     /translation="MSKHDTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     MLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMA
                     MGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIIVCQMRLRKAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQEIVFKPETAS"
     gene            54984..>55598
                     /locus_tag="RH288_001034"
     CDS             54984..>55598
                     /locus_tag="RH288_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HDV4030121.1"
                     /translation="MIKVYGVPGWGSTISELMLTLADIPYQFVDVSGFDHEGASRELL
                     KTLNPLCQVPTLALENDEIMTETAAIALMVLDRRPDLAPPVGRAERQLFQRLLVWLVA
                     NVYPTFTFADYPERWAPDAPEQLKKNVIEYRKSLYIWLNSQLTAEPYAFGEQLTLVDC
                     YLCTMRTWGPGHEWFQDNATNISAIADAVCQLPKLQEVLKRNEII"
BASE COUNT        14157 a        13145 c        14401 g        13895 t
ORIGIN      
        1 gtactggtca ggcgttttat aacgatggca caggaacaat tgttaactat ggtacaatct
       61 gcactttcgg cgtgtgccaa tcggggaatg agtacaataa tacagatgat ttcacctcac
      121 tgatctatac cggtggcgat acgattacac gaagcggaga aactgtaacg ctaaataaat
      181 ctgctgctgt gactgataag ctggctggga atgttgttaa tagcggaacg ctttccggtg
      241 atcaaattac ggtatcaagc ggtcttctgg aaaataccag cggtggcatc atcaataact
      301 tagtaaaact tgacaagggt gccgtcatta aaaatgccgg ggtgatgacg aataacgtcg
      361 atgttagcgg tggaatcctc aataatgccg gagaaatgac tgcgcaaatt accatgaatg
      421 ctggtgctga tagttcgtta gtgaacaaca ccggaaccat caataaaatc gtgcagaacg
      481 cgggggtatt caataatagt ggcagtgtaa cagggcggat gatgtcggct ggcggggtct
      541 ttaataatca aactgacggg gcgattatga gaggtgctgc gctgacaggt actgcagtgg
      601 caaataacga aggaacctgg aacctcggaa gtagtagtga gggtaacaac accgggatgc
      661 tggaagttaa taataattca gctttcaata accgcggcga gtttattctt gataacgaca
      721 agaatgctgt gcacatcaac cagtccggta cgctttataa taccggtcac atgaacatca
      781 gtaattcttc ccacaacgga gccgttaata tgtggggcgg aaatggtcgt tttatcaatg
      841 acggaacgat tgatgtttct gcgaagtcac tggtagtcag cgctaataat gccggcgatc
      901 agaatgcctt cttctggaac caggataacg gggtcatcaa cttcgatcac gacagcgcca
      961 gtgccgtgaa agtcacccac agcaacttta ttgcccagaa tgacggcatc atgaacatca
     1021 gcggcaccgg tgctgtggct atggaaggtg ataagaacgc gcagctggtt aacaatggca
     1081 ccatcaacct cggtaccgca ggcactactg acacgggtat gatcggtatg caactcgatg
     1141 ccaacgccac ggcggatgcg gtaatcgaaa acaacggcac catcaatatc ttcgccaatg
     1201 actcgtttgc atttagcgta ctgggtacag taggtcatgt ggttaacaac ggcacggtgg
     1261 tgattgccga tggggttacg ggttctggac tgatcaagca gggcgacagc atcaatgttg
     1321 aaggtatgaa cggtaacaac ggtaatagca gcgaagtgca ttatggcgac tatacgttgc
     1381 cggatgtgcc gaagcccaat acggttagtg taacgtcggg aagtgatgag gctggtggca
     1441 gcatgaacaa cctcaacggc tatgtcgtcg gtaccaacgt taacggcagc gccgggaagc
     1501 tgaaggttaa caatgccagc atgaacggcg tggagattaa cacgggcttt accgctggta
     1561 cggcagacac cactgtgagt tttgataacg tagtggaagg tagcaacctg accgacgctg
     1621 acgccatcac ctcaacgtcc gtggtatgga ctgccaaagg cagcaccgat gccagcggta
     1681 acgttgacgt caccatgagc aaaaatgcct acaccgatgt ggcaacagat gcctcggtga
     1741 atgacatcgc gaaagcactg gatgcgggtt acaccaacaa cgaactgttt accagcctga
     1801 acgtcggcac gactgctgaa ctgaacagtg ctctgaaaca ggtcagcggt agccaggcga
     1861 ccacggtatt ccgcgaagcg cgcgtgttaa gcaaccgctt tagtatgctg gcagatgccg
     1921 cgccgaaagt gggtaacggt ctggcgttca acgttgtcgc gaaaggcgat ccgcgtgccg
     1981 agttaggtaa taataccgaa tacgacatgc tggcattgcg taaaactatc gacctgagcg
     2041 aaagccagac gatgagtctg gagtacggta tcgctcgtct cgatggtgat ggtgcgcaga
     2101 aagcgggtga taatggcgtt acaggcggtt atagccagtt ttttggcctg aaacatcaga
     2161 tgtcgttcga taacggcatg aactggaata acgccttgcg ttacgacgtt cacaaccttg
     2221 acagcagccg ctcgattgca tttggcaaca cgaacaaaac ggctgatacc gacgtgaaac
     2281 agcagtacct ggagttccgc agcgaagggg cgaagacttt cgaaccgagc gaaggactga
     2341 aggttacgcc atatgcgggt gtaaaactgc gtcacacact ggaaggtggc tatcaggagc
     2401 gcaatgccgg agactttaac ctgaatatga acagtggcag cgaaacggcg gtggacagca
     2461 tcgtcgggct gaaactggac tacgcaggta aagacggctg gagcgctagc gctacgctgg
     2521 aaggcgggcc gaacctgagc tacgcgaaga gccagcgtac ggcaagcctg gcaggcgcag
     2581 gcagtcagca ctttaacgtc gatgacggtc agaagggcgg cggcatcaat agcctgacaa
     2641 gcgtcggcgt gaagtacagc agcaaagaaa gttcgctgaa tctggatgcg tacaactgga
     2701 aagaggatgg catcagcgat aaaggcgtga tgctgaactt caagaaaacg ttctaatttt
     2761 tagcatgtga tccctaaacc gcaacgctga tacaggttgc ggttttttta ttgccggatg
     2821 tggtacgtga cgcgttttgt tttgtgtctt tcaggacaat agagcaactc atccagtaat
     2881 cttgtttaca ccttcgcatt atttatctct tttcgtttct atactgattt ttcttaatcc
     2941 gttttattac agggcagggt gcgatgagca gcaatacatt tactctcggt acaaaatccg
     3001 ttaaccgtct tggttatggc gcgatgcaac tggcaggtcc tggagttttt ggccccccac
     3061 gagatcgcca cgtcgctata accgtgctgc gtgaggcgct ggcattgggc gtcaatcata
     3121 ttgataccag cgacttttat ggtccgcacg tcaccaatca gattatccgc gaagcgcttt
     3181 atccttactc tgacgacctg acaattgtca ctaaaattgg tgcgcggcgt ggagaggacg
     3241 catcctggtt gcccgcattt tctccggcag agctgcaaaa agcggtgcac gataatctac
     3301 gtaatctcgg gctggacgtg ctggatgtgg ttaacctgcg cgttatgatg ggggatggtc
     3361 atggcccagc ggaaggatcg attgaggcca gcctgaccgt gctggcagag atgcaacaac
     3421 aaggcctggt aaaacatatt ggcctgagca acgtcacacc gacgcaggtt gcagaggcgc
     3481 gcaagattgc cgaaattgtc tgtgtgcaaa acgaatacaa catcgcgcac cgtgctgatg
     3541 atgcaatgat tgatgctttg gcccacgatg gcattgccta cgtgccgttc ttcccgctcg
     3601 ggggctttac accgctgcaa tcgtccacac tttccgatgt tgctgcgagc ctgggtgcaa
     3661 caccaatgca ggtggcgctg gcgtggctgt tacagcgttc accgaatatt ttgctgatcc
     3721 cagggacgtc ttcggttgcg catttacggg agaatatggc tgctgaaaaa ttgcatcttt
     3781 ctgaggaagt gttgtctacg ttggatggta tttcgcgaga ataacgaata tacaaaaggg
     3841 aaagatgcat ttcccttttt ttctttttta atggcatgga gtgcatatgt ttaaggccag
     3901 gaattgcggc tggatacgtt tactgcccct gtttatgctg agtctaccag tacaggcgga
     3961 acttcgatgt gttgcaaatg cagttgatat tgaatcattt ttttctgcgg ctaccgctga
     4021 agataaacaa caagttgaac aagctatcaa cagtagcgtg aatcttgtcc ccttcggttt
     4081 atctgcatcg aactggaaag tgcatcgtgg cgatttagtg gtagaaggta atatagagag
     4141 taatcaaaaa ttgattgttc ttgggaattt gacagtcaaa ggtaatattt ccactttctc
     4201 tctttctaat ccatgggtta ttctcggtaa cgtgacggca acgaatatag ttgcggattc
     4261 accactgtta attaccggtt cgataaatgc aagtggactg gtatttatcg actcatatta
     4321 cgataatccg tctacgatta aggggagtat taatgcgcgt gggatattta tcaatgacat
     4381 aattgcacct gttgttgcgt cttcgacaaa tagtgaattc atggtccgtg cgagtgacaa
     4441 acatgacact gaaaatgtca aaaaagcgct gatgataata aatcctgatg catattattg
     4501 ggggctaatt aatgatgaag atgctctgaa agaaattttt aagcgaagca atattcgcat
     4561 ggcagggaat gtctgtaatc agatgaaaaa agaagcgctg tttcgcccta agccttctcc
     4621 tgagttagtg caagaattgc aaatgctgga tgaaggcaaa gttgctgcat ttgaaggacg
     4681 agacattgcg acatttgatc ttgccgtaat gcgaactctc ccaaggctta aaggaatttc
     4741 agctaaccta cgcaaacaac ttattaatag caatgatgaa caaacgattg aaagtatggc
     4801 gagatatatg cctgacaatg agattctgga gttgaccgat cagcaattgg gttaccagcc
     4861 tgttgttctg gggttgctcg accgtgaacc gctctctgtc gaaataatga cgcgaatgag
     4921 tcgtctacct gatggtgtcg gtccgttgaa tcttgcgcta cgtgaaaatc tccctctgga
     4981 tatcgtcatg actctggcga aaagagattg ggatatgatc attcaggagc tttataaaga
     5041 tgcgtggtta ttgcctgaat ccattattga tggctatatc cgcagtgatg attcctctat
     5101 tcgtcaggtc ggtgctggag gacaactcac ctacaatcag gcaatgcagt tggcgaacga
     5161 ttcatcaaac aatgttgtca caagcttagc gttcaagctg gcagagatga aacaccatgg
     5221 tcaattgttg cggatgacgc cacaagagag tgacaaagtt gcaggctatt tataccaaaa
     5281 attcgagaat gacgatgatc taatacgtgt gttattttta gcattgccag ataacttaca
     5341 gtttaatttt gttaaaagga tggagaaaaa atccccggcc tacttttgct gtcgggatat
     5401 gcaggtaatt cactctgacg ctgctttaca acggttattg acacgtttca acgatcctga
     5461 agggtggagt aatctggcga aaaatcagta tctgagcacg tcgatgaaac aaaaaatttg
     5521 gcaacgtgct ttatcgcatc ggaaaaataa tccgaaagca gattcagatg catatgaaac
     5581 cagcgctgat atgattttgt ctgagctgat tagccacggc gaagttgatg accagatgct
     5641 attaaatgcc accgccctga tacgttcgga cgactgggac tttttagaga gtgcattaat
     5701 tagttgggat aatttacccg ctgttgttct caaggaatta cagcaaaaca cgccacgcaa
     5761 tgatatttgg gcgaagtttt ttctgaggca ggaaaacagt tcccgtgcac aggttgacga
     5821 agcgttacgt gtttattatg cactagaccc cgatgcgtta gcacaactgg atgtactggc
     5881 aaaacaaccg gatcgtatat ggtggagtac actggcgaaa agcaatctca catttttcaa
     5941 gttcggcgca cttaacaacc gccacacacc gcctgcagta ctggcggcag aaattgatcc
     6001 cgagtggtgg attgtggcga tgaataatcc ccgttttcca gttgatgtat taaaggcgag
     6061 gctgaaacgt gatcctttgc tggcgttaga gcttgttaac cctgaactgg atttagtccg
     6121 ccagctggcg cttaacggta agacgcgcgc aatacgggaa caagcgatga gaaaacttga
     6181 tgagttgtat tgatccacaa cgtaatgttt tttaactatc tgattaattg gggataatca
     6241 ttcctgacag tgagtcccca ataccttgat atattctgaa tttttaatga aacggcgtgt
     6301 tgcgatatct ccgtcagggg aattgatgca ccatagcgca aaccgaatta tcaaggattg
     6361 ataatgacgc tctaccagat aaaaccgctc tttcagtcgc tgttaaggcc gacgatgttt
     6421 tggctttata agcaccacgt tacagcgaat cacatcactc ttgctgcact ggcgctttct
     6481 cttcttaccg gattgctgtt gatgttggcg gccatcctct ttttgctatt gcccatcgtg
     6541 ctttttatcc gtatggcgct caatgcgctg gatggcatgt tggcgcgtga gtgcaaccag
     6601 caaacacgtc tgggggcgat tttgaatgag actggcgatg ttatttccga tattgcgctc
     6661 tatttaccat ttttattttt accggaaagt aacgcatcac tcgtgatact catgttattt
     6721 tgcaccatat tgaccgagtt ttgcggttta ctcgcgcaga cgattaacgg tgttcgcagt
     6781 tatgccggtc catttggcaa aagcgatcgc gcgttaatat ttggtctgtg gggtctggcc
     6841 gttgccattt atccacagtg gatgcagtgg aataatcttt tatggagcat tgcttcaatt
     6901 ctgcttctct ggactgcgat taatcgttgt cggagtgtgc ttcttatgag cgctgaaata
     6961 taatgctgga aaaatctctg gcaacacttt tcgcgttgtt aattttagca acgctgataa
     7021 accgttttct gctatggcgg ttaccggaga gaaaaggggg tgaggttaca ttacgtattc
     7081 gtacctggtg gggcatcgtc atttgttttt caatggtgat ttcaggtcca cgctggatga
     7141 cgttgacgtt ttttgcgctg ataagttttc tggcattgaa agaatattgt acgcttatat
     7201 ctgtacattt tccgcgttgg ttatattggg gtattcctct taactatttg cttatcggtt
     7261 ttaattgctt tgagctgttt ctgttattta tacctttggc tgggtttctg atattagcca
     7321 ccgggcaagt tttagtggat gacccctctg gttttctgca taccgtgagc gccatttttt
     7381 ggggctggat aatgaccgtt ttcgccttga gtcatgccgc ctggttatta atgttgccaa
     7441 ccacaaatat ccagggcggg gcgttactgg tgttatttct tttggcatta atcgagtcaa
     7501 acgatattgc acagtattta tggggaaaat cctgcggcag aagaaaagtg gtccctaaag
     7561 tcagcccggg aaaaacattg gaaggtctga tgggcggcgt catcaccatc atgattgcgt
     7621 cactgattat cggaccgtta ctgacaccgc taaatacatt acaggcatta ttagcgggtt
     7681 tgttaattgg tattagtggt ttttgcggcg atgtcgtgat gtcagccatc aaacgagata
     7741 ttggtgttaa agatagcgga aaactattgc caggacatgg cggactcctt gacaggattg
     7801 actcattaat tttcaccgct ccggtatttt tttattttat acgctactgc tgttactgaa
     7861 ggaaaataga gaaaatggaa aattcacgca tccctgggga acattttttt accaccagtg
     7921 ataatacagc gttgttttat cggcactggc ccgctttaca gcccggggcg aaaaaggtca
     7981 tcgtcttatt tcatcgcggg catgaacatt ctggtcgtct acaacatctc gttgatgaac
     8041 tggcgatgcc agatactgct ttttatgcct gggatgcccg agggcatgga aaaagttcgg
     8101 ggccgcgtgg ttatagccca tctcttgcgc gttcagtgcg ggatgtcgat gaatttgtcc
     8161 gttttgctgc cagcgacagc caggttggac tggaagaggt ggtagtgatc gcgcaaagcg
     8221 tcggcgcagt gctggttgcc acatggattc atgattatgc acctgcaatt cgcgggctgg
     8281 tgctggcttc tccggccttt aaggttaaat tgtatgtgcc gctggcacgt cctgcgctgg
     8341 cgttatggca tcgtctgcgt ggtctgtttt ttattaattc ctatgtgaaa ggacgctatt
     8401 tgacccacga tcggcaacgg ggggcgagtt tcaataatga tccgctgatc acacgggcga
     8461 ttgccgttaa tatcttgctc gatctctaca aaacgtctga acgtattatt agagatgcgg
     8521 cggcgattac gctccccacg caacttctga tatcaggcga tgactatgtg gtgcatcgcc
     8581 aaccgcagat tgatttttat cagagattac gtagccctct gaaagagctg catctgctgc
     8641 caggctttta tcacgacacg ttgggtgaag agaacagggc gctggcattt gaaaaaatgc
     8701 aaagctttat tagtcgttta tatgctaaca aatcgcaaaa atttgattat cagcatgaag
     8761 actgcacagg accatcagcg gatcgatggc ggctactttc tggtggaccc gtgccattat
     8821 cgccggttga tttagcgtat cgctttatgc gaaaggcgat gaaattgttc gggacgcact
     8881 cttcgggcct gcatctcgga atgagcaccg gctttgattc aggcagttcg ctggattatg
     8941 tctatcaaaa tcaaccgcaa ggtagtaacg cattcgggcg tttagtcgac aaaatctacc
     9001 tgaacagtgt tggctggcgc ggtattcgcc agcgcaaaac ccatttacaa atactgatta
     9061 aacaagccgt tgccgatctc cacgccaaag gtttagccgt ccgcgtggtt gacattgccg
     9121 cagggcatgg gcgctatgta ctggatgcgc tggcaaacga gcctgccgta agcgatattt
     9181 tgttacgtga ttacagcgag ttaaatgttg cacaggggca agagatgatt gctcaacggg
     9241 gaatgtctgg gcgggtgcgt tttgaacagg gcgatgcgtt taacccggag gaactcagcg
     9301 cgttaactcc gcggcctacg ctggcgattg tctctggcct gtatgagctt tttcccgaaa
     9361 atgagcaggt aaaaaactca ctcgcaggtc ttgccaatgc catcgaaccg ggcggcattc
     9421 tcatctacac cgggcagccg tggcaccctc aactggagat gattgccggg gtgttaacca
     9481 gtcataaaga tggtaaaccg tgggtaatgc gcgtgcgttc gcaaggggag atggattcac
     9541 tcgtgcgtga tgccggattt gataaatgca cacaacggat tgatgagtgg ggtattttta
     9601 cggtttcgat ggcggtgcgt cgtgataact gaacgtcgga acgtattgct acaaggcgct
     9661 ggctggttat tgttgctggc cccgtttttc ttcttcacct atggatctct taatcagttc
     9721 accgcggttc aggaccttaa cagccatgat atccccagtc aggtattcgg ttgggaaacg
     9781 gcgatccctt ttcttccctg gactattgtt ccttactgga gtctggatct tttatatgga
     9841 ttttcgctgt tcgtttgtag cacgacattc gaacagcgcc gacttgtcca ccggcttatt
     9901 ctggcaacgg taatggcctg ctgcggtttt ttgctctatc cgctgaagtt tagttttatc
     9961 cgtcctgaag tgagtggggt gacgggatgg ctattttcgc aacttgaact gtttgatctg
    10021 ccttataacc agtctccttc gctgcatatt attctctgct ggctactttg gcgtcacttt
    10081 cgtcagcatc tggctgagag gtggcgtaaa gtctgcggcg gatggttttt actcatcgcc
    10141 atttcgacgc tgacgacctg gcagcatcat tttattgatg tcatcacagg gctggcggta
    10201 ggtatgttga ttgactggat ggtgcccgtc gaccgtcgtt ggaattatca gaaacctgat
    10261 caacgtcgaa tcaaaatagc actgccctat gtcgtaggcg cgggctcgtg cattgtattg
    10321 atggagctaa tgatgatgat tcagttatgg tggtcagtct ggttatgttg gccagtatta
    10381 tcgctactca taattggccg tgggtacggt gggcttggcg cgataacaac agggaaagat
    10441 agtcagggga aactaccgcc cgccgtttac tggctgacat tgccctgccg catcgggatg
    10501 tggctgtcta tgcgttggtt ttgtcgtcgc ctggagccgg tgagcaaaat gactgctggt
    10561 gtttatttag gggcgtttcc acgacatatt ccggcacaga atgcggttct ggacgtcacc
    10621 tttgaattcc ctcgcggacg agccacaaaa gatcgactct atttttgtgt accgatgctg
    10681 gatctggtgg ttccggaaga gggggagctc cgacaggccg tggcgatgct ggaaacatta
    10741 cgcgaagagc aaggcagcgt tctggtccat tgtgcattgg gattatcgcg cagtgcgctg
    10801 gtggtggcgg catggttgtt atgttacgga cactgtaaaa ccgttaatga agcgattagc
    10861 tatattcgag ccagacgccc gcagattgtg ctgacagacg agcacaaagc gatgctgaga
    10921 ttatgggaaa acaggtaagt ggattgagat gtggactgaa tatctacagt ccacatcaag
    10981 accgtgtccg gttatgcaga aacaatgctg tcgatggctg cttttgcgtc agactgtgct
    11041 ttcgctgcca tttccggacc gtatgcgatc ccttcggcga agacaaattt cacatcggta
    11101 atgccgataa agccgaggaa cgtggacaga tacggcgtca ccaggtccgt tggtccatct
    11161 ttgtggatcc cgccgcggct ggtaataacg atggcttttt tacccgttac cagaccttcc
    11221 ggaccgttct cggtatagcg gaaagtaacg cctgcgcggg caaccaggtc aaaatagttt
    11281 ttcaactgag tcgagatgtt gaagttatac atcggtgccg caataacgat aacgtcgtgg
    11341 gctttcagct cggcaatcaa ctcatcggaa agtgccagag cttcctgctg acgcggagtc
    11401 agcggcgcat cgctcggacg cagagcgcca accagttcgc catccagtac cggaatcgga
    11461 tttgcagcca ggtcgcgaac ggtgatttca tcagcggagt gcttttcgcg ccattgttca
    11521 acaaaataat cggacaactg attagactga gagtaccctg ccaggatgct ggatttaaga
    11581 actaatacct tgctcatggt gtttccttat agatgtttga atgggcgatg ccccgttgct
    11641 tgttgacact ttattcacaa tcctgccaca gagatagcgc aataaatcga agcctatgtt
    11701 cgaatttatt gaacaacgca tagaaagccg cgatgtggta ctctatatct atcatttaaa
    11761 agaaaattaa tcaggcagac tactgcccac taacgttatg acagaacaac aaaaattgac
    11821 ctttacggcc ttgcagcagc ggctggattc gctgatgctg cgtgacagac tgcgtttttc
    11881 tcgccgtctg cacggcgtga agaaggttaa aaatcctgat gcacaacagg ccattttcca
    11941 ggagatggcg aaagagattg accaggcggc agggaaagtc ctgctgcgtg aagcggcacg
    12001 accggaaatt acttatcctg acaatttacc ggttagtcag aaaaaacagg acattctcga
    12061 agcgattcgt gatcaccagg tggtgatcgt cgccggggaa acgggttctg gtaaaacgac
    12121 tcagttaccg aaaatctgta tggagctggg gcgcgggatt aaaggactga tcggccatac
    12181 ccagccgcgt cgtctggcgg caagaacagt ggcgaaccgt attgcggaag agctgaaaac
    12241 ggagccgggc ggttgcatcg gttacaaagt gcgtttcagc gatcacgtaa gtgataacac
    12301 gatggtcaag ctgatgaccg acggtatcct gctggcggag atccagcaag accgcctgct
    12361 gatgcagtac gacactatca ttattgacga agcgcacgaa cgcagcctga atatcgattt
    12421 tttgctcggc tatttgaaag agttgctgcc gcggcgtcct gacctaaaaa tcattatcac
    12481 ttccgcgact atcgacccgg aacgcttttc gcgccacttt aataatgcgc cgattattga
    12541 agtctccggt cggacctatc cggtggaagt gcgctatcgc ccgattgttg aagaagccga
    12601 tgacaccgag cgcgatcagt tgcaggcgat ttttgacgcc gtagacgaac tgagtcagga
    12661 aagccatggc gacattctga tctttatgag cggcgagcgg gaaatccgcg ataccgccga
    12721 tgcgctgaac aagctgaact tacgccatac cgaaatcttg ccgctttatg cgcggctttc
    12781 gaacagcgaa caaaataggg tattccagtc gcacagcgga cggcgcattg tgctggcgac
    12841 caacgtcgcg gaaacgtcgc tgaccgtacc ggggattaaa tacgttatcg accccggtac
    12901 agcgcgtatc agccgctaca gctatcgcac caaagtgcag cgtttgccga ttgagccgat
    12961 ttcccaggcg tctgccaatc agcgtaaagg ccgctgtggt cgtgtgtccg aagggatctg
    13021 tattcgtctc tattccgaag acgatttcct ctcgcgcccg gagtttaccg atccggagat
    13081 tctgcgtacc aacctggcct cggttatttt gcagatgacc gcgctggggc tgggcgatat
    13141 cgctgcgttc ccgtttgtcg aagcaccgga taaacgcaat atccaggatg gcgtgcgtct
    13201 gctcgaagag ctgggcgcga tcaccactga tgaacaggcc agcgcctata aactgacgcc
    13261 gctcggtcgc cagctctcgc agttgcctgt cgacccacgt ctggcgcgta tggtgctgga
    13321 agcgcaaaaa catggctgcg tgcgtgaggc gatgattatc acgtccgcgc tctccattca
    13381 ggatccgcgc gaacgtccga tggacaaaca gcaggcatcg gacgaaaaac atcgtcgctt
    13441 ccacgacaaa gagtctgact ttctcgcgtt tgtgaatctg tggaattatc ttggcgagca
    13501 gcaaaaggcg ctttcttcca acgccttccg tcgcctgtgt cgtaccgatt atctcaacta
    13561 tctgcgcgtg cgcgaatggc aggatatcta cacccagttg cgtcaggtgg tgaaagaact
    13621 tggcattccg gttaacagcg aaccggcgga gtatcgcgaa attcacattg cgttgctgac
    13681 cggtttactt tcccatatcg gcatgaaaga tgccgataaa caagaatata ccggcgcacg
    13741 taacgcgcgt ttctccatct tccccggttc tggtttattc aaaaaaccgc ctaaatgggt
    13801 aatggtggcg gaactggtag aaaccagccg cctgtggggg cgcattgctg cgcgtatcga
    13861 cccggaatgg gtggagccag ttgctcagca tttgattaaa cgcacctaca gcgaaccgca
    13921 ctgggaacgg gcgcagggcg cggtgatggc aacggaaaaa gtcactgttt atggtttgcc
    13981 gattgttgcc gcgcgcaagg tcaactacag ccagatcgat ccggcgttat gtcgtgaact
    14041 ctttattcgc cacgcgctgg tggaaggtga ctggcagacg cgtcacgcat tcttccgtga
    14101 aaacctgaaa ctacgggcgg aagtagaaga gctggaacac aaatcacgtc gccgcgatat
    14161 tctggttgat gacgaaacgt tgtttgagtt ctacgaccag cgcatcagcc acgatgtaat
    14221 ctccgctcgc cacttcgaca gctggtggaa aaaagtcagc cgcgaaacgc ctgatttgct
    14281 caactttgaa aaaagcatgt tgatcaaaga gggcgcagaa aaaatcagca agctggatta
    14341 cccgaacttc tggcatcagg gcaatctcaa gctgcgtttg agctatcagt ttgagcccgg
    14401 cgcggatgct gacggtgtga ccgtacatat tccgctgccg ttacttaacc aggttgagga
    14461 aagcgggttt gaatggcaga tccccggtct gcgccgcgaa ctggtgattg ctctgattaa
    14521 atcgttgccg aaaccggtac gccgtaattt tgtacccgcg ccaaactatg ccgaagcgtt
    14581 tttaggccgc gtcaaaccgc tggagttacc gttgctcgac agccttgagc gcgagttacg
    14641 gcggatgacc ggcgttaccg ttgaccgcga agactggcac tgggatcagg tgcccgatca
    14701 cctgaaaatt accttccgcg tggtggatga caaaaacaag aagctaaaag aagggcgctc
    14761 gctacaagat ctgaaagatg cgctgaaagg caaagtgcag gaaacgctat ctgcggtggc
    14821 ggatgacggt atcgagcaga gcggcttaca tatctggagt tttggtcagc tgccggaaag
    14881 ctacgaacag aagcgtggca actacaaagt gaaggcgtgg ccggcgctgg tggatgagcg
    14941 cgacagtgtg gcgatcaaac tgtttgataa cccgctggag caaaagcagg caatgtggaa
    15001 cggtcttcgc cgtctactgc tgctgaatat tccatcgcca atcaaatatt tacatgaaaa
    15061 gttaccgaac aaagccaagc tgggactgta ctttaacccg tatggcaaag tgctggagct
    15121 gatcgacgac tgtatctcct gcggtgtgga taaattgatc gacgccaatg gtggcccggt
    15181 ctggacggaa gaaggctttg ctgcgctgca tgaaaaagtg cgtgccgaac tgaacgacac
    15241 ggtggtggat attgcgaagc aggtcgagca aatccttacg gcagtgttca atatcaacaa
    15301 acgtctgaaa gggcgggtgg atatgaccat ggcgctgggg ctttctgaca ttaaagcgca
    15361 gatgggcggg ttggtatatc gcggttttgt cactggtaac ggcttcaaac ggctgggcga
    15421 cacgctgcga tatttgcagg cgattgaaaa acggctggaa aaactggcgg ttgatccaca
    15481 tcgcgaccgt gcgcagatgc tgaaagtcga aaacgtccag caggcgtggc agcaatgggt
    15541 caacaaactg ccgcccgcac gtcgtgagga tgaagacgtg aaagagatcc gttggatgat
    15601 agaagagttg cgcgttagtt acttcgctca acaacttggt acgccttatc cgatttcaga
    15661 taagcgtatt ttgcaggcga tggagcagat tagcggttaa ccctgctatt tgcctgataa
    15721 agaaaaaacc cggtaagcat ttagcgccgg gttttttatt aattctaaaa cggtaagggt
    15781 aaaaattcag gaattcagaa aaatacaatt ctctgctgca agatgaataa tgtttatcta
    15841 cagcatttcc ttaaaagata tgtcaggctt gcggagtggc ggttaaggac atacgatttc
    15901 ctcctttcag agtgctccgc ttctcactat tatctcacgc agtattctta agggaacgat
    15961 aaggaggaac catgaacatt accccgtttc cgacgctttc gccggcaact atagatgcca
    16021 taaatgttat cggacagtgg ctggcgcagg atgatttctc cggtgaggtg ccgtatcagg
    16081 ccgattgcgt gatccttgca ggcaatgcgg ttatgccgac tatcgatgcg gcatgtaaga
    16141 ttgcccgcga tcagcaaatt cctttactga ttagtggtgg tatcggtcac tcgacaactt
    16201 ttttgtatag cgccatcgca cagcatccgc actacaacac tatccgcacc actggcagag
    16261 cagaagcgac catcctggcg gatatcgctc atcagttctg gcacattccg catgaaaaaa
    16321 tctggattga agaccagtca acaaactgcg gtgaaaacgc acgctttagc atcgcgctat
    16381 tgaatcaggc cgtagaacga gttcatacgg ctatcgttgt tcaggacccc accatgcagc
    16441 ggcgcacgat ggcgacgttc cgccgtatga ctggggacaa tcccgatgca ccacgctggt
    16501 taagttatcc cggattcgtt cctcagttag gaaataacgc agacagtgta atctttatta
    16561 atcagttaca aggattatgg ccagttgagc gttatctctc actactcact ggcgagctgc
    16621 cgcgtttacg cgatgatagc gatggctacg gtccccgcgg gcgagatttt atcgttcacg
    16681 ttgattttcc ggcagaagtc atccatgcat ggcaaacgct gaaacatgat gcggtgctca
    16741 tcgaggcgat ggaaagtcgc tcgttacgtt aaaaattgcc cgtttgtgaa ccacttgttt
    16801 gcaaacgggc atgactcctg acttttattt ctgcctttta ttccttttac acttgttttt
    16861 atgaagccct tcacagaatt gtcctttcac gatgccgtct ctctgatgat tgatgttaat
    16921 taacaatgta ttcaccgaaa acaaacatat aaatcacagg agtcgcccat gtcagtaccc
    16981 gttcaacatc ctatgtatat cgatggacag tttgttacct ggcgtggaga cgcatggatt
    17041 gatgtggtaa accctgctac agaggctgtc atttcccgca tacccgatgg tcaggccgag
    17101 gatgcccgta aggcaatcga tgcagcagaa cgtgcacaac cagaatggga agcgttgcct
    17161 gctattgaac gcgccagttg gttgcgcaaa atctccgccg ggatccgcga acgcgccagt
    17221 gaaatcagtg cgctgattgt tgaagaaggg ggcaagatcc agcagctggc tgaagtcgaa
    17281 gtggctttta ctgccgacta tatcgattac atggcggagt gggcacggcg ttacgagggc
    17341 gagattattc aaagcgatcg tccaggagaa aatattcttt tgtttaaacg tgcgcttggt
    17401 gtgactaccg gcattctgcc gtggaacttc ccgttcttcc tcattgcccg caaaatggct
    17461 cccgctcttt tgaccggtaa taccatcgtc attaaaccta gtgaatttac gccaaacaat
    17521 gcgattgcat tcgccaaaat cgtcgatgaa ataggccttc cgcgcggcgt gtttaacctt
    17581 gtactggggc gtggtgaaac cgttgggcaa gaactggcgg gtaacccaaa ggtcgcaatg
    17641 gtcagtatga caggcagcgt ctctgcaggt gagaagatca tggcgactgc ggcgaaaaac
    17701 atcaccaaag tgtgtctgga attggggggt aaagcaccag ctatcgtaat ggacgatgcc
    17761 gatcttgaac tggcagtcaa agccatcgtt gattcacgcg tcattaatag tgggcaagtg
    17821 tgtaactgtg cagaacgtgt ttatgtacag aaaggcattt atgatcagtt cgtcaatcgg
    17881 ctgggtgaag cgatgcaggc ggttcaattt ggtaaccccg ctgaacgcaa cgacattgcg
    17941 atggggccgt tgattaacgc cgcggcgctg gaaagggtcg agcaaaaagt ggcgcgcgca
    18001 gtagaagaag gggcgagagt ggcgttcggt ggcaaagcgg tagaggggaa aggatattat
    18061 tatccgccga cattgctgct ggatgttcgc caggaaatgt cgattatgca tgaggaaacc
    18121 tttggcccgg tgctgccagt tgtcgcattt gacacgctgg aagatgctat ctcaatggct
    18181 aatgacagtg attacggcct gacctcatca atctataccc aaaatctgaa cgtcgcgatg
    18241 aaagccatta aagggctgaa gtttggtgaa acttacatca accgtgaaaa cttcgaagct
    18301 atgcaaggct tccacgccgg atggcgtaaa tccggtattg gcggcgcaga tggtaaacat
    18361 ggcttgcatg aatatctgca gacccaggtg gtttatttac agtcttaatg agtgaaagag
    18421 gcggaggttt tttcctccgc ctgtgcgcgt cagagtttag cgaatttttc gagggtgcga
    18481 ataagctgtg tgacgaagcc atattcgtta tcgtaccagg cgaccgtttt caccagttgt
    18541 aaatcgccca cggcggtaat ttccgtttgc gtggcatcaa acaccgaacc gaaatggctg
    18601 ccaatgatat cggaagagac tatttcttca tcggtataac caaatgactc gttattggtg
    18661 gttgcttgtt taagtgcgtt attcacctct tcggcagtca cttttttccg agaatcgata
    18721 ccagttcagt gaccgaacct gttttcaccg gcacgcgttg cgcatgacct ttcagtttgc
    18781 cgctcagttc cgggatcacc agaccaatgg cttttgccgc ccccgtagtg tggggaatga
    18841 tattttctgc cgctgcgcgt gaagcacgta aatctttacc acgcgggcca tccaccagtg
    18901 actgggtgcc agtataggca tgaatggtcg tcatcgtgcc gacttctatc ccgaaactgt
    18961 catgcaaggc tttggccatc ggcgcaagac agttagtggt gcatgacgcc acggaaacaa
    19021 tggtgtcgtt gccatccaga gtgtcgtcat tgacgttata aacgatagtt ttcatttcac
    19081 cggcaggggc ggaaatcaac accttcttcg caccagcatc aagatgcgcc tgcgatttct
    19141 cggcggaggt ataaaagcca gtacattcga caatgatttc tgcacctttc gctttccacg
    19201 gaatattttt agcctctttt tcggcgtaaa ccgcgatact tttcccatca acgataagtg
    19261 aatcttccgt aaaatcaacg ctccagggga atggtccgta gtttgaatca tgtttcagca
    19321 ggtaggcgag aatttatggg gaagtgagat cattaatagc gacaacgtct atgttgcttt
    19381 tgacttcaag taatcgaccc aacaccagtc gaccgatacg accaaaaccg ttaataccaa
    19441 ctttactcat ggttttctcc tgtcaggaac gttcggatga aaattgatcc tttccaggct
    19501 tagaccagga tggcgggatg ggcaatctcc attctcacag tgaaacgtaa cgtactgaaa
    19561 acgggtgaac aatatttaat gaaattttga gaaaagcccg ttatgttaac ggaaaattat
    19621 gttaaagcag gaaatgttat ggaaaataaa tattcaaggt tacaaatcag cattcactgg
    19681 ctggtctttt tactggttat cgcagcgtat tgcgcaatgg agtttcgtgg tttcttccca
    19741 cgtagcgatc ggccactcat caacatgatt catgtttcct gtggcatctc aattctcgtg
    19801 ctgatggtcg ttcgtctttt gttaaggctg aaatacccaa ccccgccgat tatacctaag
    19861 ccaaaaccga tgatgacggg actggcgcat ttgggacatt tggtgattta tctcctgttt
    19921 attgcgctgc cagtgattgg tttggtgatg atgtataacc ggggcaaccc gtggtttgcg
    19981 tttggtttga cgatgcctta cgcttcagag gccaatttcg aacgggtaga tagcttaaag
    20041 tcgtggcatg aaacgctggc gaatctggga tattttgtca tcgggttgca cgctgcggct
    20101 gcactggcac accactattt ctggaaggac aacacacttc tacgcatgat gccgcgtaaa
    20161 cgttcctgaa ggatatttaa agaaaacgcc tgtactaaaa ccgacccgtg gtacaggcga
    20221 agaatacggg tctacatcgg aagcgcctat tatatttatt tgtatgataa ataaaaccat
    20281 aatccttgcc catacgtcca tctggcttat ttttaatcaa ttcacccgat ctttgatctc
    20341 atcaacggta tcaaaataaa ccagcgtata acgttcaaat cgaacataag attcgataaa
    20401 ccatggaggt tatatgaaaa aactggcact tattttgttt atgggaacgc ttgtttcctt
    20461 ttatgccgat gccgggcgca aaccctgttc tggttcgaaa ggggggatct cacactgtac
    20521 ggcaggcggc aaatttgtct gtaatgatgg ttctattagt gcatcgaaaa aaacatgcac
    20581 taactgaagt gtaaaagggg tgccatgaga aaatgaatct gctagtcaaa tgcgcgggga
    20641 aaatccccgc gcttgccctt acctggacgt gcaggccatg agcgcagcaa cctccttatc
    20701 accgtcccgg aaccgcagtt cgtagagcgt ttgtcgggtc aggagtgtga atgtcagaat
    20761 cgtaatgcag ataatgagca gacacaccac cagagggttg tgcttcatag cctttctcct
    20821 tgccggatgg cgggtaagag gctaagatct gaattgctag gttcattcgt tggcctcggt
    20881 tgatagaaat atcggtcggg gccttcgtct ttctgattcc cggttagcct gaaaacagaa
    20941 agtctcaggc acccgcaggc atcctatgag gtttccttag ggacgaaaat aatcacttca
    21001 cgaaattgcg tgctgttttc cagaattttt cgtcattcgg gttagccagt ttagccattc
    21061 gttactctct tcattccaat agcattaatt ttctatgcaa taattgttgt aaaaatgtga
    21121 cgcaaagagg tttttggtca taagtaatta ccgtcaagtg ccgatgactt tctatcagga
    21181 gtaaacctgg acgagagaca acggtaatga atacaactcc ctcacagcga ttaggttttt
    21241 tgcatcacat caggttggtt ccgttatttg cctgcattct aggcggtatc ttagttctat
    21301 tcgcattaag ttcagcccta gctggctatt tcctctggca ggccgatcgc gatcagcgtg
    21361 atgttactgc ggagattgag attcggaccg ggttagcgaa cagttcagat tttttgcgtt
    21421 cagcccggat caatatgatt caggccgggg ctgcgagtcg tattgcggaa atggaagcaa
    21481 tgaagcgaaa tattgcgcaa gccgaatcgg agattaaaca gtcgcagcaa ggttatcgtg
    21541 cttatcagaa tcgaccggtg aaaacacctg ctgatgaagc cctcgacact gaattaaatc
    21601 aacgctttca ggcttatatc acgggtatgc aacctatgtt gaaatatgcc aaaaatggca
    21661 tgtttgaagc gattatcaat catgaaagtg agcagatccg accgctggat aatgcttata
    21721 ccgatatttt gaacaaagcc gttaagatac gtagcaccag agccaaccaa ctggcggaac
    21781 tggcccatca gcgcacccgc ctgggtggga tgttcatgat tggcgcgttt gtgcttgccc
    21841 tggtcatgac gctgataaca tttatggtgc tacgtcggat cgtcattcgt ccactgcaac
    21901 atgccgcaca acggattgaa aaaatcgcca gtggcgatct gacgatgaat gatgaaccgg
    21961 cgggtcgtaa tgaaatcggt cgcttaagtc gtcatttaca gcaaatgcag cattcactgg
    22021 ggatgacagt agggactgtt cgacagggcg cggaagagat ttatcgtggc accagcgaaa
    22081 tttcagctgg caatgcggac ctgtcatctc gcaccgaaga acaagcggcg gctatcgaac
    22141 aaactgccgc cagcatggag caactcactg cgacggtgaa acagaatgcg gataacgcgc
    22201 atcatgccag caaactggcg caagaggctt ctattaaagc cagcgatggc gggcagacgg
    22261 tttccggtgt agtaaaaacg atgggcgcta tctccacgag ttcgaagaaa atttctgaga
    22321 tcaccgccgt catcaacagt attgctttcc agacgaatat tctggcactg aatgctgccg
    22381 ttgaagccgc gcgagcgggt gagcaagggc gtggatttgc cgttgtcgcc agcgaagtac
    22441 ggacactcgc aagtcgcagc gctcaggcgg cgaaagagat tgaaggcttg atcagtgaat
    22501 cagtcaggtt aattgacctg gggtcggatg aggtggcaac ggccgggaaa accatgagca
    22561 ctattgttga tgccgtcgcg agtgtcacac atatcatgca ggaaatcgcc gccgcctcgg
    22621 atgaacaaag tagaggcata acgcaggtta gccaggcgat ttctgaaatg gataaggtga
    22681 cgcaacagaa tgcttctctg gtagaagagg cctcagcggc ggcggtgtcc cttgaagaac
    22741 aggcggcacg attaactgag gcggtggatg tattccgtct gcacaaacat tctgtgtcgg
    22801 cagaacctcg cggagcgggt gaaccagtta gtttcgctac ggtgtgaaaa tgttcaagga
    22861 gggatcgaca gatcccttca cctttcagaa cggcattgat tttcgaatag cgttaatcat
    22921 caactggcaa ccagaagaga acgtcgcatc tacgcgggtc agtattccaa tcggttcgcc
    22981 tgcaccatgt cccggaacag gcagggccac cagcgtggca tgacgcaggt cgtcttttac
    23041 agcgccagaa gggacaaacc acacgtaatc gtattcaacc gtaagttgac gagatagcga
    23101 agcagacagc gtttcgatac aacccgaagg aattttacag ccctggctct gcactaatgc
    23161 atctgaatgc tggcgtggcg cagtgccttc tggtgataca acgaccggcc attccagcac
    23221 ccggcttagc gttacgttct cctgaagtag cgggtgatta gggcggacaa ccagcttcaa
    23281 cgattcaaga aacagcagtt cgtaattaag cccggtcatc agttcaggat ctgacatccg
    23341 accaatgccg atatcgattt ccccggtttt taaacccgcc agaatcatag ggttactcat
    23401 tgtcgcaact tgcaaggtcg tctctttttg ttgctgatga aactgaccta taaccgaagg
    23461 taatatcccc agtgccgcag taggtagtgc accaaccctg acgacatcat tattaagacc
    23521 ttctttacga tgaagcgacc gtccggcagt gttgatggcg tcaagaactc tgactgcatg
    23581 cgttaaaaat tgttcgccgg gtaaggtaag ttgcgccccc tgacgaccac gctcaaacaa
    23641 gcgagcgcca gtcagctgct ccagttcatt caatgtctta gagagcgcag gttgactcaa
    23701 attaagggtt tcagccgcgc gccccaaagt tccttgttgt gcgacagcta cgaatgtatg
    23761 aaggtggcgc aaacggatgc gctgactaaa cagactattt ttttccataa gcgatgttaa
    23821 aaacgaagcg gtgtcgctga caagtgaagt tgtttgatta tgataacttg attgcaaaat
    23881 attattaaca attaaagcaa ttatgttaca gcaaaatgga taatattgat gttttcgcgg
    23941 cgagatcaca gtttgtaaat tcttcccgca agagtgaatg cggttaccta cactccagat
    24001 tactgaccac tggaggcaga cactatggcg aacagcatca cggcggatga gattcgggaa
    24061 cagttttcgc aggcaatgtc agccatgtac cagcaagaag ttccgcaata tggcacgctg
    24121 ctggaactgg tagctgatgt gaatctggct gtgctggaaa acaatcctca actgcacgaa
    24181 aaaatggtaa atgcagacga gctggcgcga ctgaatgttg aacgtcatgg ggcgattcgc
    24241 gttgggactg cacaagagct tgctactctt cggcggatgt ttgccattat ggggatgtac
    24301 ccggtgagct attacgatct ctcgcaggca ggggtgccgg tacattcgac agcatttcgg
    24361 cccattgatg atgcttctct ggcgcgtaat cccttccgcg tttttacctc cttactccgc
    24421 cttgagctta tcgagaacga aattttgcgc cagaaagcgg cggagattct gcgtcagcgc
    24481 gatatcttca ccccacgttg tcgacaactg ttagaggaat atgagcagca gggcggtttt
    24541 aacgaaacac aggcacagga gtttgtgcag gaagccctgg aaacgtttcg ctggcaccag
    24601 tcagcaacgg tagatgaaga aacctatcgc gcattgcaca acgaacatcg gttgattgct
    24661 gatgtggtct gttttcctgg atgccatatc aaccacctga cgccacgtac gctggatatt
    24721 gaccgggtgc agtcgatgat gcctgaatgc ggaattgaac ccaaaattct catcgagggg
    24781 ccgccgcgcc gcgaggtacc gattttacta cgccagacca gctttaaagc actggaagag
    24841 acggtgttgt ttgcggggca gaaacagggc acgcataccg cgcgctttgg tgaaattgag
    24901 cagcgtggcg tggcattaac gccgaaaggg cgacaactgt atgatgatct tctgcgtaac
    24961 gctggaaccg ggcaggataa tctcactcac caaatgcatt tacaggaaac cttccgcact
    25021 tttcctgaca gtgagttttt aatgcgtcag caagggttgg catggttccg gtaccgtctg
    25081 acgccttcgg gtgaggcgca tcgtcaggcg attcatcctg gagacgatcc acagccctta
    25141 attgaacgtg gttgggtagt ggcgcaaccc atcacctatg aagatttctt gcccgttagc
    25201 gcggcgggga tcttccagtc aaatctgggt aatgaaacgc agacacgcag tcacggtaat
    25261 gccagtcgcg aagcatttga gcaggcgttg ggttgtccgg ttttggatga gttccagctt
    25321 taccaggaag cggaagaacg cagtaaacgt cgctgtggtt tgctttaaaa tctgaccatc
    25381 cgcctttgca aaaatttgcc tgattttaca aacgaatcag gctcatccca tcgacataaa
    25441 aaaaatgccg atttatgcat attctctcag ttcaacaatt ggattattaa taaatattgt
    25501 ctagagtgag cggtcataaa taagcacttt cttgccgctg aaaacgacca gcgcgggacc
    25561 attcacaaca ccagaaggac tcactttcag gtatggatcg tagacgattt attaaaggtt
    25621 caatggctat ggccgccgtg tgcggtacca gcggcattgc ttctcttttt tctcaggcgg
    25681 cattcgcggc agattctgat attgccgacg ggcaaaccca gcgttttgac ttctccattc
    25741 tacagtcaat ggcgcacgac ttagcgcaaa cagcgtggcg tggtgcgcct cgtccgttac
    25801 ctgacacgct ggcgacaatg acgccgcagg cttataacag tattcaatac gacgccgaaa
    25861 aatcgctctg gcataacgtt gagaaccgtc aactggacgc tcagttcttc catatgggaa
    25921 tgggattccg tcgccgcgtt cgtatgtttt ctgtagatcc agcaacacat ctggcgcgtg
    25981 aaattcactt tcgcccggag ttgttcaaat acaacgatgc aggtgttgat acaaaacaat
    26041 tagaagggca aagcgatctc ggctttgccg gttttcgcgt gtttaaagcc cccgaactgg
    26101 cgcgccgtga tgtagtatca tttctcggcg cgagttattt ccgcgccgtt gatgatacat
    26161 atcaatacgg tttgtcggcc cgcggcctgg cgatcgacac ttacaccgac agtaaagaag
    26221 agttccccga ctttaccgcc ttctggtttg atacggtaaa accgggggca actaccttta
    26281 ccgtttatgc gttgctcgat agcgccagca ttactggtgc ctataagttc actatccatt
    26341 gtgagaaaag tcaggtgatt atggatgtgg aaaatcacct gtatgcgcgc aaagacatta
    26401 aacagctggg cattgcgccg atgaccagta tgttcagctg cggtactaat gaacgtcgga
    26461 tgtgcgatac aattcatccg caaattcatg actctgatcg tctgtccatg tggcggggca
    26521 acggcgagtg gatttgccgt ccgctgaata atccgcaaaa attgcagttc aatgcttaca
    26581 ccgacaacaa cccgaaaggg tttggtttat tgcaactgga tcgtgacttc tcccattatc
    26641 aggacattat gggctggtat aacaaacgcc caagtctgtg ggtggaaccg cgtaacaagt
    26701 ggggtaaggg caccatcggc ctgatggaaa tcccaacaac gggcgaaacg ctggataaca
    26761 ttgtctgctt ctggcagcca gaaaaagctg taaaagcagg tgatgagttt gcattccagt
    26821 atcgtctgta ctggagtgcg caaccgcctg ttcattgccc attagcgcgc gttatggcga
    26881 cgcgtaccgg catgggcggt ttctcggaag gttgggcgcc aggtgaacac tatcccgaaa
    26941 aatgggcgcg tcgttttgcc gtcgatttcg ttggtggtga tctgaaagct gccgcgccaa
    27001 aaggcattga gccggtgatt acgctttcca gtggggaagc gaagcaaatc gaaattctct
    27061 atattgaacc catcgatggt tatcgtattc agtttgactg gtatccgact tcggactcca
    27121 ctgatccggt cgatatgcgg atgtatctac gttgtcaggg ggacgctatc agtgaaacat
    27181 ggctgtatca gtatttcccg ccagcgccgg ataaacgtca gtatgttgac gaccgcgtga
    27241 tgagttaatc gttttttctt cggcaccttc ttcgggaggt gccgtctggt taaacacgat
    27301 cccgctcgca tttttcccta agttaaatga gtaatctgat ggtgtgtatt tcagatacac
    27361 cttgtcagcc actaacaggg agtgcgtatg tttccagaat accgagattt aatatcccgt
    27421 ctgaaaaacg aaaatcctcg ctttatgtcc ttgttcgata aacacaataa acttgatcat
    27481 gaaattgcca gaaaggaagg ttccgacggt cgagggtaca atgcggaagt ggtccgcatg
    27541 aaaaaacaaa agctacagtt aaaagatgag atgctcaaaa tcctgcagca ggagagcgtc
    27601 aaagaggtgt aaactttcct aagccgccag ccaggcggct tttttaacaa ctgcatggat
    27661 tgactggaga taagatgact gaaacgataa aagtaagcga atcacttgaa ttacatgctg
    27721 ttgcagaaaa tcacgtcaaa cctctttatc agttaatctg taaaaataaa acctggttac
    27781 agcagtcgct aaactggccg cagtttgttc aaagtgaaga ggacacgcga aaaacggtgc
    27841 agggtaatgt gatgttgcat caacgcggct atgccaaaat gttcatgatt ttcaaagaag
    27901 atgaacttat cggcgttatc tcgtttaatc gtattgaacc actgaataaa accgctgaaa
    27961 taggctactg gctggacgaa tctcatcagg ggcaggggat catttctcag gcgctgcagg
    28021 cattgattca tcattacgcc cagtctggtg aacttagacg cttcgtgatc aaatgtcggg
    28081 tggacaatcc gcaaagcaac caggtcgctt tgcgcaatgg ttttatcctt gaaggttgcc
    28141 tgaaacaggc tgagttcctg aatgatgcct atgatgatgt gaacttatac gcgcgtatta
    28201 tcgattcaca ataaccctgc cagcggcgtt cgcgtaatgc gctcctcgcc gttaatgact
    28261 tttggaccac ggacatgaac cgtgtcgcca tcaaaggctt caacgacggc gtggtcggtt
    28321 aactccacat ggttttcaat tatcaccgca cctgtaatac ggctctcacc ttgtatgaca
    28381 acgtgctcgt cgagcagaat cggtccgcca cgtaccacgg catttccgcc aaccaagaca
    28441 tgatgtttta acacacaatt accttccaca atggcatatt ccgccacctg cgaactgtaa
    28501 tgaatcgtcg gaatggcatc ttcttctatg ccagctttca cctgcgcgtg accgtagact
    28561 ttagcgcaat cgcatagcca gacattgttc tcttcattac cttcaatact ggcaaaatca
    28621 aaaacttcgg cgcgatgttc aataaaagca taccggacga cggcatcgcc ataaatttgt
    28681 gcctggtgga caatacgcga ggcgctaacc cttgcgcgat cataaatttg gagcaggagt
    28741 tgatggtcgg gcgttaagcc ttgtgcggcg acgatcatag aatgttgatc aattaaggcg
    28801 tgaccaaata ttctacattg cccgtaaact aatgagtcat gaatggtgac gctgtcactt
    28861 atatatgcac cctggctgat ttcactatta tcgatccaga cgttatccgt tgcgtaaacc
    28921 tctccccaca gcacgctggt gccggtgata cgcgtattac cggaaatcac cgctccgccg
    28981 aacgcaatag cattctggtc gtaaatccag caatttcctt cttgtgctaa caccgtttcg
    29041 cgatcgatcc agccgccagc ggttcctgct atcacatcgt taaaatcgct aatggcgata
    29101 atctgccgta ataacacatt ttttttagtg ccatcttcct gataactaaa ggctcgctgt
    29161 tcttcactta gacgatattt gcgcatagcg ttttcccaca ggtgacttac tataaccgta
    29221 gcaaattctg cggctctggc tatgctcgag aaaattccat aaaatgcatt tcaaatatac
    29281 tttataaatt aaacaaaatg agtaagaaga tgcagagcga taaagtgctc aatttgccgg
    29341 caggctactt tggtattgtg ttggggacga tagggatggg atttgcctgg cgctatgcca
    29401 gccaggtttg gcaggtcagc cactggttag gggatgggct ggtgattctg gcgatgatca
    29461 tctggggatt attgactagc gcatttattg cccgactcat acgctttccg catagcgtgc
    29521 tggcggaagt tcgccatcca gtgctgagca gttttgtgag tttgtttccg gcaacgacga
    29581 tgctggtggc gattggtttt gttccgtggt ttcgcccact ggcggtgtgc ctgttcagtt
    29641 ttggtgtcgt ggttcagttg gcttatgccg cctggcaaac tgcgggatta tggcgcggat
    29701 ctcaccctga agaagctacc acgcctggac tgtatctgcc gacagttgcc aacaacttta
    29761 tcagcgcaat ggcctgtggt gcgttgggct acaccgacgc cggtctggtg tttttaggcg
    29821 caggcgtttt ctcatggcta agccttgaac cggtgatctt gcagcgtctg cgcagttcgg
    29881 gagaattacc cacggcactg cggacatcac tcggcattca gctcgctcct gcgctggtgg
    29941 cttgtagtgc ctggctgagc gtcaacggcg gcgagggtga cacgctggcg aaaatgcttt
    30001 tcggttatgg actgctgcaa ctgctgttta tgctacgtct gatgccatgg tatctctccc
    30061 agccatttaa tgcttcattc tggagtttct cgttcggcgt atctgcactg gcaaccaccg
    30121 gtttgcatct ggggagtggc agcgataatg gatttttcca tacgctggcg gtgccgctgt
    30181 ttatctttac caattttatt attgcaatac tgctcatccg tacttttgcg cttctgatgc
    30241 agggaaaatt gttagtcaga accgagcgcg ccgttttaat gaaagcagag gacaaagaat
    30301 gatcattcgt gacgaaaact attttactga taaatatgaa ttaacccgca cacactctga
    30361 agtactggaa gcggtgaaag tggttaaacc gggtaaaacg ctggatctgg gctgtggcaa
    30421 tggtcgtaac agtctttacc tggcagccaa tggttatgat gttgacgcat gggataaaaa
    30481 tgccatgagt atcgccaacg tcgagcgcat taaatccatt gaaaatctgg ataatttaca
    30541 cacccgagtc gttgatctga ataacctcac atttgataga cagtacgatt ttattctttc
    30601 gactgtggtg ctgatgttcc ttgaggctaa aaccatcccc gggttgattg ccaatatgca
    30661 acgttgcact aaacctggtg gttacaacct gattgtggcg gcgatggata ccgctgatta
    30721 tccatgtacc gtcggcttcc cgtttgcctt caaagaggga gaattacgtc gatattacga
    30781 aggctgggag agggtgaaat acaatgaaga cgtcggcgag ctgcaccgca ccgacgccaa
    30841 cggtaatcgt attaaactgc gtttcgccac gatgctggca cgtaaaaaat gacccggtaa
    30901 gcacaaaacg cgtgaaaatt ccccacgctg agatgattta ctgttcttct tttcggtaag
    30961 catatttttt atcgaaggga tgtgaaatta atcacagtag tcgaagtttt tagcagctta
    31021 acttactgaa atttaagtac tgatgattga cttagcccct ttttcggcat tgactatgtc
    31081 gtctgaaaag gggctgaaaa atttattttc accaacactt tttttgccac aacacgaagc
    31141 ggcgcttttt gctataactt agaaagtaat ataatcatct caggaaacta ttcatgcgta
    31201 ccacatcatt tgcgaaagtt gcagctttat gcggcttatt ggctctgtct ggttgtgcct
    31261 ctaaaatcac ccagccagat aaatattctg gttttttaaa caattactct gatttaaaag
    31321 aaacaacctc ggctacaggt aaacctgttt tacgttgggt agacccgagt tttgatcaaa
    31381 gcaaatatga cagcatcgtc tggaacccaa tcacttatta tccggtaccg aaaccgtcga
    31441 cccaggtagg gcagaaagtt ctggataaaa ttttgaacta taccaacacc gaaatgaaag
    31501 aagcgatagc gcagcgtaaa ccactggtta ccaccgctgg gccgcgtagt ctgattttcc
    31561 gtggggccat taccggtgta gataccagca aagaagggct gcaattctat gaagtggttc
    31621 ctgttgcatt agtggttgcg gggacgcaaa tggctacagg ccaccgtacc atggatactc
    31681 gcctctattt tgaaggtgag ctgattgatg cagcgactaa taaaccggtt atcaaagtcg
    31741 ttcgtcaggg cgaaggtaaa gacctgaata acgaaagtac gccaatggct ttcgaaaata
    31801 ttaaacaagt tattgatgac atggcgaccg atgccaccat gtttgacgtt aacaaaaagt
    31861 agttccagac gcgccatcgt tagatggcgc tttttatccg gtgcgccgta aaaccccatc
    31921 cttcagggcg gggatataag gcgcggtttt ccacctgacc aggtgtttgc tgttgttcaa
    31981 tgtattggcg gatgacggat attggcgcac ctccgcagct actggcaaaa tagccaggac
    32041 tccacaaaac gcctttgtag taatacctga atgcaatatc tggtcgatct cgtcgcagtc
    32101 acctacccga tacgcctttg aggctgttta ccagactgga tatcgccagt ttgggaggat
    32161 agttaattaa caaatggacg tgatctggtt cgccatccat ttcaaccagt tcagcttcaa
    32221 aatcagcaca tacatttgaa aagtaagtgc gtagtttttc tgtcgcgtca tggtcaaaaa
    32281 tctggcgtcg gtatctggtg acaaagagca ggtgaacatg catcaggaaa acacaatgcc
    32341 ttccacgccg gatatcggtt tcttttttca cagaccaaag tatcatttga cctgtgaaac
    32401 gattacaggc atttaaattc cagttaagac ccggtggtca acaggagtgt gaaatgaggc
    32461 gcttcgcagg cgcatgtcgt ttcgttttca atcgtgctct ggcacgtcag aatgagaatc
    32521 atgaggccgg taataaatac atcccttacg ggaaaatggc ttcctggctg gttgagtgga
    32581 aaaatgccac tgaaacgcaa tggcttaaag attctccctc acagccattg caacagtcac
    32641 tgaaagacct tgagcgggct tacaaaaact tcttccggaa gcgggctgct tttccccgat
    32701 tcaaaaagcg gggacagaat gatgcattcc gctacccgca gggcgttaag ctcgatcagg
    32761 aaaacagccg tatttttctg ccgaaactgg gctggatgcg ctaccggaac agccgtcagg
    32821 tcacgggtgt tgtgaaaaat gtcactgtca gccagtcctg cggtaagtgg tacatcagta
    32881 ttcagacaga aagtgaagta tcaactccgg ttcacccttc agcatcaatg gtcgggctgg
    32941 atgctggcgt ggctaaactc gccacgctgt cagatggcac agtctttgag cctgtaaaca
    33001 gttttcagaa aaaccagaag aagctggcga gacttcagcg acagttaagc cgcaaggtca
    33061 aattcagcaa caactggcaa aagcagaaac gcaaaataca gcgactgcat tcctgtatcg
    33121 caaatatccg cagggactac cttcacaaag tcacaacggc cgtcagcaaa aaccacgcaa
    33181 tgatagtcat tgaggatttg aaggtcagca acatgtcaaa gtcagcagcg ggtacggtca
    33241 gccagccggg gcgcaatgtc cgggcaaaat caggtttaaa ccgttcgata ctggatcagg
    33301 gctggtatga aatgcgccgc cagcttgcgt acaagcagct ctggcgtggc ggtcaggtgc
    33361 ttgctgttcc gccagcgtat acaagccagc gttgcgcgta ctgtggtcat acagcgaaag
    33421 agaaccgcct gtcacaaagt aaattcagat gccaggtatg tggatataca gcgaacgccg
    33481 atgtaaatgg cgctcgcaac attttagcgg cggggcacgc cgttcttgcc tgtggagaga
    33541 tggtgcagtc aggccgcccg ttgaagcagg aacccaccga aatgattcag gcgacagcct
    33601 gaacgtagca gggatccacg tccttcaggg cgtggaggat gtcaatatcg gtttctgtca
    33661 gcgattaaat tcaacaccac gtaacaaacg cctccggcaa ttaatcccca aaacgcagaa
    33721 ccaatcccga ccagcgtcaa tccacttgcc gttaccagaa atgccaccac cgccgcgtct
    33781 cgctcacgct cattatgcag cgcctgatac aaactgccgc cgatggtact taacagcgcc
    33841 agacctgcca gcatctggat ccaacttacg ggcagggcag ccatcatccc ggtaatggca
    33901 ctaccaaaca gacctgcgag caaatagaaa atgcctgcaa cggcagcggc cagccaacgt
    33961 tgatctttat ccggatgcgc ttccgggctt tggcaaatag ccgcggtgat tgccgcaata
    34021 ccgacggaat aaacgccgaa aggggaaaaa accagtgcca gcaatccagt aaatacaatt
    34081 aatggcgaaa caggagccga atatccagct gctttcattg ctgcgatacc cggtgcgttt
    34141 tgcgatgcca tcgtcaccag aaaaaggggg agtgcaacgc tcaggctgtg agcaaacgaa
    34201 aaatcagggg taatataagt ggggagaacg ggtttaaaga caacatcagt tgtgacaacg
    34261 tcaccttgcg cgatgacgat cacgatccca ataatcatcg cggcaattac cgcatagcgc
    34321 ggcgcaacgg ccttggttgc cagccatacc agcaacatac ttccacacaa cgtaaattga
    34381 ccgtccagac tggcaaacgc ctgtaaacca aagcgtaata aaatcccggc aagcattgcc
    34441 gccgcaagcg agtgcggaat aatgcgcatc agacgagcaa agagtcccgt tatgccgcag
    34501 aggactatta gcgcgttggt gacaataaaa acgccgatgg cttcgttaag tgttagtccc
    34561 tgcaatccgg tgaccaacaa agccgcgcca ggcgttgacc atgcggtgag aacaggtacg
    34621 cgataccata atgtcagagt cagcgtactg acgcccattg ccagccccag cgccgtcatc
    34681 cagccagaga tttgtgcagt ggtggctccg gcgacaatcg ctgcttgcca gattattgcc
    34741 gctgaactgg cgtagccaat taataccgcc agaaaccccg ccagtagcgt gggtggagga
    34801 atagaaaaca gacgcatagt cacctcgtgc gttatagcgt acaggcaccg tagcatttgt
    34861 ccgttataac gcacaagtga taaacttccg ttttgccgga ggagtcgcat ggaaaatctc
    34921 gctcgctttt tatccaccac acttaaacaa ctacgccagc agcgcggctg gagtctttcg
    34981 cgactggcag aagcgacggg cgtttctaaa gcaatgttag ggcagattga gcgtaatgag
    35041 tccagtccga cggtcgcgac attatggaaa attgccaccg ggttgaacgt accattttca
    35101 acatttattt ctccgccgca gtccgctacg ccttcagttt atgatccaca acagcaggcg
    35161 atggtgatca cttcgctgtt tccttatgat ccacaactct gctttgaaca cttctcgatt
    35221 cagatggcat ctggtgcaat aagcgaatcg acgccccatg agaagggggt aatcgaacat
    35281 gtcgtcgtca ttgatggaca acttgatctg tgcgttgatg gggaatggca gacccttaat
    35341 tgtggggaag gcgttcgatt tgctgcagac gtcacgcata tctatcgtaa tggtggggag
    35401 caaaccgtac attttcattc cctcatccat tacccgcgca gttaagcggg aaaactattt
    35461 cgcaacgtcg cgcttgtggc taaaatagcc gccatttttc agctactgga taagaatgtg
    35521 accgtatctt ctcatcgact tgaactgtta agcccggcac gcgatgccgc cattgcccgc
    35581 gaagctattt tgcacggtgc cgatgctgtt tatatcggcg gccctggttt tggtgcccgt
    35641 cataatgcca gtaatagctt gaaagatatt gccgagctgg tgccgtttgc ccatcgttat
    35701 ggtgcaaaaa ttttcgtcac gcttaacacc attttgcatg atgatgagct ggaacccgcg
    35761 caacggctga ttactgacct ctaccagacc ggtgtcgatg cgctgattgt tcaggatatg
    35821 gggattctgg aacttgatat tccgccgatt gaactgcacg ccagtacgca gtgcgacatt
    35881 cgtacagttg aaaaagcgaa gttcctctct gatgttggct tcacgcagat tgtgctggcg
    35941 cgagagctga atcttgatca gatccgcgcg attcaccagg ctacggacgc gaccattgaa
    36001 ttctttattc atggggcact gtgcgtggcc tattcgggtc agtgctacat ttctcatgcg
    36061 caaacagggc gtagcgccaa ccgtggcgat tgctcgcagg cgtgccgttt gccatacaca
    36121 ttgaaagacg atcaggggcg ggtggtttcc tatgaaaaac atctgctgtc gatgaaagat
    36181 aacgatcaga ctgccaacct cggcgcgctg attgatgctg gtgtacgctc cttcaagatt
    36241 gaagggcgtt acaaagatat gagctacgtg aagaatatca ccgcccatta tcgccagatg
    36301 cttgatgcca ttattgaaga acgtggcgat ctggcgcgcg cttcatcagg tcgtactgaa
    36361 catttctttg ttccatcgac ggaaaagact ttccaccgtg gtagcacaga ttattttgtg
    36421 aatgcccgta aaggcgatat tggcgcgttc gattcgccga aatttatcgg cctgccggta
    36481 ggcgaagtag tgaaagtggc gaaagatcat ctcgatgttg ccgttaccga gccactggca
    36541 aatggcgatg gcctgaacgt gttgattaaa cgtgaagtcg tcggttttcg tgccaatacg
    36601 gtcgagaaaa ccggagaaaa tcagtaccgc gtctggccca atgaaatgcc agcagatttg
    36661 cacaaaattc gtccacatca cccactaaac cgtaatcttg atcataactg gcagcaggca
    36721 ctgacaaaaa cctccagcga acgtcgggtg gcggtagaca ttgaactggg cggctggcag
    36781 gaacaactga ttctgaccct caccagtgaa gagggtgtca gcatcacgca tacgctggac
    36841 gggcagttcg acgaagccaa taacgccgaa aaagcaatga acaatctgaa ggatggtctg
    36901 gcaaaactgg ggcaaaccct ctattacgcc cgcgatgtgc aaattaattt gccgggggcg
    36961 ctgtttgtac caaacagtct gttaaaccag ttccgccgtg aagctgctga catgctggat
    37021 gctgcgcgtc ttgccagtta ccagcgcggc agccgtaaac cggttgctga tcctgcgccg
    37081 gtttatccgc aaacgcatct gagtttcctc gcgaacgtat acaaccagaa agcgcgtgaa
    37141 ttttatcatc gctatggtgt gcagctgatt gacgcggcgt atgaagcaca tgaagagaag
    37201 ggcgaagtcc cggtgatgat caccaagcat tgtctgcgct ttgcctttaa tctgtgcccg
    37261 aaacaggcga aaggcaatat caaaagctgg aaggcgacgc caatgcaact ggttaacggc
    37321 gatgaagtat taacgctaaa gtttgattgc cgcccatgcg agatgcacgt cattggcaaa
    37381 atcaaaaatc acatactgaa aatgccgtta ccgggaagcg tagtggcatc cgtaagtccg
    37441 gatgagctgc tgaaaacatt gccgaagcga aaagggtaaa acgccagttt tctggttact
    37501 cacaacttat tgaatctgca tgatattgcc tgccgggtaa ggcgttacgc cgcatccggc
    37561 atcaaatgac tcaacgttgt cccgcttctg gtttgcgcga tttttgccag taaaaatgct
    37621 cgcgcaaacc ttccgccgac tcttccgcca cagcacgcaa ttcatcgctg tccgcttcat
    37681 gacgcagctg atgatccaca ttctttaccc acacaaattc atgtcctttg tgccctgcca
    37741 tgagttgtcc tgaaaacaga gcacacgtta ataagacaac cgataacgcc ttcgtaaaca
    37801 tcctgccacc tttttcttac cttttgccgc tatgatgccg atcgtttctt gaggttatta
    37861 ttcagttttg caaattagcg caaagaaatt ctggaatctt ccttcctgat tttgcattgc
    37921 attctgccgt tgcggcgatt tagtgctatt ttcgagcaaa ttacacacgg aggtaaacac
    37981 taatgtttac tttgttgata tactcagcgg cagggaggcg atgtgaaaca aagcgagttc
    38041 agacgttggc tcgaatctca gggcgtcgat gtagcgaatg gcagcaacca tttgaaactc
    38101 aggtttcatg ggaggcgcag tgtcatgccg cgtcacccct gcgatgagat taaagaacca
    38161 ttgcgtaaag caatcctgaa acaactcggt ttgagttaat cgccaattaa aaaggttaat
    38221 gacatgcgag agacagtcga aattatgcgt tatcccgtca ctcttacacc cgcgccggaa
    38281 ggcggttata tggtttcttt tgtggatatc cctgaagcgt tgacccaggg cgaaactgtc
    38341 gctgaagcga tggaagcggc aaaagatgct ttactgaccg catttgattt ttattttgaa
    38401 gataacgagc ttatcccttt accttcgcca ttaaatagtc acgatcactt tattgaagta
    38461 cctttgagcg tcgcctctaa ggtattgctg ttaaatgctt ttttacagtc agaaatcact
    38521 cagcaagagt tagccaggcg aattggcaaa cctaaacagg agattactcg cctatttaac
    38581 ttgcatcatg cgacaaaaat cgacgccgtc cagctcgcgg caaaggcgct tggcaaagag
    38641 ttatcgctgg tgatggttta attacagtta acgaaaagtt gtcattttta acaactgata
    38701 tagactgccg aatcatctgc acataattac gattcgataa tgaaaaaata ccagcagctt
    38761 gcagaacaat tacgcgagca gattgcgtcg ggtatctggc aacccggcga tcgtttgcct
    38821 tcgttgcgtg accaggtggc gctttcaggc atgagcttta tgactgtcag ccatgcctat
    38881 cagttgctcg aaagtcaggg atatattatc gcacgaccgc agtcgggtta ttacgttgcg
    38941 ccacaggcaa taaaaatgcc gaaagcgcca gtcattccag tcactcgaga tgaagcagtc
    39001 gatatcaaca cttatatttt tgatatgttg caggccagtc gcgatccgtc ggtcgttccg
    39061 tttgcctcgg cctttcccga cccgcgactt ttccccctcc aacaactaaa ccgctcgctg
    39121 gcgcaggtaa gcaaaaccgc cacagcgatg agcgtgattg aaaacttacc gccaggaaac
    39181 gcagaactgc gtcaggctat tgctcgtcgc tatgccttac agggcatcac catttctcct
    39241 gatgaaattg tcattactgc cggggcgtta gaggcattaa acctcagttt gcaagcggta
    39301 actgaaccgg gcgattgggt gatagtagag aatccttgtt tctacggtgc gttgcaggcg
    39361 ctggagcggc tacggctgaa ggcgttatcg gtggcgacgg atgttaaaga agggatagat
    39421 cttcaggcgc tggaactggc gttgcaggag tatccggtga aagcgtgctg gctgatgact
    39481 aatagccaga atccactcgg atttacctta acgccgcaaa aaaaagcaca actggtggcg
    39541 ttgctcaatc agtacaacgt aacgctgatt gaagatgacg tttacagcga actttatttt
    39601 ggacgggaaa aaccgctgcc tgcgaaagcg tgggatcgcc acgatggcgt tttgcattgc
    39661 tcttcgtttt cgaaatgtct ggtgcctggt tttcgtattg gttgggtcgc cgccggaaaa
    39721 catgcacgta aaattcaacg cttgcagttg atgagtacgc tttccaccag ctcaccgatg
    39781 caacttgcgc tggtggatta cctttccacg cgccgatacg acgcccatct tcgtcgcctg
    39841 cgtcgccagc ttgcggaacg taaacaacgt gcctggcagg cactgctgcg ttatctgcct
    39901 gcggaagtga aaattcatca taatgacagt ggttactttc tctggttgga gctccccgag
    39961 ccgttagatg ccggcgaatt aagcctggcg gcactgacgc atcatatcag tattgcgccg
    40021 ggtaaaatgt tttctaccgg tgaaaactgg tcacgttttt tccgttttaa taccgcgtgg
    40081 cagtggggag agcgtgaaga acaggcggta aaacaattag gcaaacttat tcaagaacgg
    40141 ctgtaatagc gtttaattta attcctctta gattgggtaa tatgaatttc gaatagcagt
    40201 catatttcct aactccttga ctatactcca gaagataacc ttacagacgg cataatgcgc
    40261 ggtagctcac aacctgaata aattttctca ggggcgaagg tgtgcctgca agccgccgtc
    40321 tatggttaaa caaggagata tttttacggc acggcggctg aacaattaat tacgacagga
    40381 gtaagacctt atgagcaaga catttgcccg cagcagcctg tgtgcgctca gcatgacaat
    40441 aatgaccgct cacgccgccg aaccgcctac caatttagat aaaccggaag ggcgactgga
    40501 tattatcgcc tggccgggat acatcgaacg cggacaaact gataaacaat acgactgggt
    40561 aacgcagttc gaaaaagaga caggctgcgc ggtgaatgtg aaaaccgccg cgacttccga
    40621 tgaaatggtc agtctgatga ccaaaggggg ttacgatctg gttacggcat ccggcgatgc
    40681 ctcgctgcgt ttgattatgg gtaaacgcgt gcagccgatt aataccgcat tgattcccaa
    40741 ctggaaaacg ctcgatccgc gcgtggttaa aggcgactgg tttaatgttg gcggcaaagt
    40801 ttacggcaca ccttaccaat gggggccgaa cctgctgatg tacaacacta aaaccttccc
    40861 gacgccgccg gatagctggc aagtggtttt tgttgagcaa aatctgccgg acggcaagag
    40921 caataaaggc cgcgttcagg cttatgatgg ccctatctat attgcggacg ctgcgttgtt
    40981 cgttaaagcc actcagccgc agttgggcat cagcgatccg tatcaactca ccgaagaaca
    41041 gtaccaggcg gtgctgaaag tgctgcgcgc tcaacacagt ttgatccatc gctactggca
    41101 tgacactacc gtgcaaatga gcgatttcaa aaacgagggt gtggttgctt ccagtgcctg
    41161 gccctatcag gccaacgccc tgaaagccga aggccagcct gttgctaccg ttttcccgaa
    41221 ggagggtgtt accggttggg ctgataccac catgctgcat agcgaagcga aacatccggt
    41281 ttgcgcctac aaatggatga actggtcatt aacgccaaaa gtgcagggcg atgtggcggc
    41341 ctggtttggc tcgttaccgg tagtgccgga agggtgtaaa gccagtccgt tattaggcga
    41401 aaaaggttgt gaaaccaacg gttttaacta tttcgacaaa atcgccttct ggaaaacgcc
    41461 tatagcagaa gggggcaagt ttgttcccta cagtcgctgg acgcaggatt acattgccat
    41521 tatgggcggt cgctaacttc gctggggtgc tttatgacgt acgcagtgga gtttgacaac
    41581 gtctcgcggt tgtacggtga cgtgcgcgca gtagatggcg tcagtattgc gataaaagat
    41641 ggtgagttct tctctatgct ggggccgtcc ggctccggca aaaccacctg cctgcgcctg
    41701 attgctggct tcgaacagct ttccggcggg gctatctcta tctttggtaa acccgccagc
    41761 aatctgccac cgtgggagcg ggacgtgaat actgtctttc aggactacgc gctatttccg
    41821 catatgtcga ttcttgacaa tgtcgcctat gggctgatgg tcaaaggcgt gaataaaaag
    41881 cagcggcacg caatggcgca agaggcgctg gagaaagtgg cgttggggtt tgtacatcaa
    41941 cgtaaaccgt cacaactttc tggtggtcag cgccagcggg ttgctatcgc cagagcattg
    42001 gtgaatgaac cgcgcgtatt gctgttggat gaaccgctcg gcgcactgga tctcaaattg
    42061 cgtgagcaga tgcagctgga actgaaaaaa ctgcaacagt ctctcggtat cacttttatc
    42121 ttcgttaccc acgatcaggg cgaagcgtta tcgatgtccg atcgtgtggc ggttttcaat
    42181 aatggacgca ttgagcaggt cgattccccg cgcgatctct atatgcgccc gcgcacgccg
    42241 tttgttgccg ggttcgttgg tacatcgaat gtttttgatg gactgatggc agagaaactt
    42301 tgtggcatga cgggaagctt cgccctgcga ccggaacata tccgcctcaa cacccctggt
    42361 gaactgcagg ccaatggcac gatccaggcg gtgcaatatc agggcgcggc aactcgtttt
    42421 gaactgaaat tgaacggcgg tgaaaaactg cttgtgagtc aggccaatat gacaggcgaa
    42481 gaactgcctg ccacgctcac gcccggacaa caggtgatgg tttcctggtc gcgtgatgtg
    42541 atggtgccgc tggttgagga gaggtgaatg gcgatgaatg tattgcaatc accttcacgt
    42601 ccaggtctgg gtaaggtgtc cggtttcttc tggcataatc cggggctggg gctgttttta
    42661 ctgctgcttg gcccgctaat gtggtttggc attgtctatt tcggctcgct gctgacactg
    42721 ttatggcagg gattttatac ttttgacgat ttcaccatgt cggtaacgcc ggaactgacg
    42781 ctggcgaata tccgtgcgct gtttaatccg gcgaattacg acatcattct ccgcacgctg
    42841 actatggctg tggcagtcac tatcgccagc gccattctgg cttttccaat ggcgtggtat
    42901 atggcgcgct ataccagcgg gaaaatgaaa gcgttttttt atattgcggt aatgttgccg
    42961 atgtgggcga gctacattgt taaagcctat gcctggacgt tattgctggc aaaagatggc
    43021 gtggctcagt ggtttttaca acatcttggg ctggaaccac tgctgactgc gttccttaca
    43081 ttacctgcgg tgggcggaaa tacgctgtca acttccgggc tggggcgctt tctggtgttt
    43141 ctctatatct ggttgccgtt catgatcctg cccgttcagg cggcgcttga gcgtttgccg
    43201 ccgtcattgt tgcaggcgtc ggctgatctc ggcgcacgtc cacgacaaac ctttcgctat
    43261 gtggtgctgc cgctggcaat cccgggtatt gccgctggct ctatctttac cttctcactc
    43321 acactgggcg attttatcgt cccgcagctg gttggtcctc caggatattt tatcggcaat
    43381 atggtttatt cccagcaggg ggcgattggc aatatgccga tggcggcggc attcaccctg
    43441 gtgccgatta ttctcatcgc actgtacctg gcgttcgtga aacgtctggg agcgttcgat
    43501 gcactctgaa cgcgcaccgt ttttcctcaa actggcggcc tggggcggcg ttgttttcct
    43561 acattttccc atcctgataa tcgccgccta tgcgtttaac actgaagatg cggcgtttag
    43621 ttttccaccg cagggcctga cgctgcgctg gtttagcgtg gcagcacagc gtagtgatat
    43681 tcttgatgcc gtgacactgt cacttaaagt ggcggcgctg gcgacattaa ttgcgctggt
    43741 gttagggacg ctggcagctg ccgcgctgtg gcgacgagac tttttcggca aaaacgccat
    43801 ttcgctgtta ctgctgctgc ccattgcgct gccgggcatt gtcactggtc tggcgttatt
    43861 aaccgccttt aaaaccatca atctggagcc gggatttttc accatcgtgg tcggtcatgc
    43921 gactttttgt gtagttgtgg tgtttaacaa tgtcatcgcc cgttttcgcc gcacctcctg
    43981 gagtctggtt gaggcgtcaa tggatcttgg ggccaatggc tggcaaacct tccgctacgt
    44041 agtgttgccg aatctcagtt cggcgttact ggcaggagga atgctggcgt ttgccttgtc
    44101 gttcgatgaa atcatcgtta cgacctttac ggcaggtcat gaacgaacgt taccgttgtg
    44161 gttgctcaat cagcttgggc gaccgcgtga tgtaccggta actaacgtgg tggcactgct
    44221 ggttatgttg gtaacaacct tgccgatcct gggggcctgg tggctaaccc gcgaaggcga
    44281 caatggtcaa taaccactga tacaggaata tgctatgcaa cataagttac tgattaacgg
    44341 agaactggtt agcggcgaag gggaaaaaca gcctgtctat aatccggcaa cgggggacgt
    44401 tttactggaa attgccgagg catccgcaga gcaggtcgat gctgctgtgc gcgcggcaga
    44461 tgcagcattt gccgaatggg ggcaaaccac gccgaaagtg cgtgcggaat gtctgctgaa
    44521 actggctgat gttatcgaag aaaatggtca ggtttttgcc gaactggagt cccgtaattg
    44581 tggcaaaccg ctgcatagtg cgttcaatga tgaaatcccg gcgattgtcg atgtttttcg
    44641 ctttttcgcg ggtgcggcgc gctgtctgaa tggtctggcg gcaggtgaat atcttgaagg
    44701 tcatacttcg atgatccgtc gcgatccgtt gggggtcgtg gcttctatcg caccgtggaa
    44761 ttatccgctg atgatggccg cgtggaaact tgctccggcg ctggcggcag ggaactgcgt
    44821 agtgcttaaa ccatcagaaa ttaccccgct gaccgcgttg aagttggcag agctggcgaa
    44881 agatatcttc ccggcaggcg tgattaacat actgtttggc agaggcaaaa cggtgggtga
    44941 tccgctgacc ggtcatccca aagtgcggat ggtgtcgctg acgggctcta tcgccaccgg
    45001 cgagcacatc atcagccata ccgcgtcgtc cattaagcgt actcatatgg aacttggtgg
    45061 caaagcgcca gtgattgttt ttgatgatgc ggatattgaa gcagtggtcg aaggtgtacg
    45121 tacatttggc tattacaatg ctggacagga ttgtactgcg gcttgtcgga tctacgcgca
    45181 aaaaggcatt tacgatacgc tggtggaaaa actgggtgct gcggtggcaa cgttaaaatc
    45241 tggtgcgcca gatgacgagt ctacggagct tggaccttta agctcgctgg cgcatctcga
    45301 acgcgtcagc aaggcagtag aagaggcgaa agcgacaggg cacatcaaag tgatcactgg
    45361 cggtgaaaag cgcaagggta atggctatta ctatgcgccg acgctgctgg ctggcgcatt
    45421 acaggacgat gccatcgtgc aaaaagaggt atttggtcca gtagtgagtg ttacgccctt
    45481 cgacaacgaa gaacaggtgg tgaactgggc gaatgacagc cagtacggac ttgcatcttc
    45541 ggtatggacg aaagatgtgg gcagggcgca tcgcgtcagc gcacggctgc aatatggttg
    45601 tacctgggtc aatacccatt tcatgctggt aagtgaaatg ccgcacggtg ggcagaaact
    45661 ttctggttac ggcaaggata tgtcacttta tgggctggag gattacaccg tcgtccgcca
    45721 cgtcatggtt aaacattaag gataatattg cagatcgtaa gagtatgaga tgatcttgcg
    45781 tactgtcaga gcactgattt ctctgacagt acgtgctgcg tgcaaaatca ctacatcaaa
    45841 taaaccagcc aaatctcata gagataagag taaacaaacc aacagcagca aagaaattta
    45901 tcagtactac agttctactg gaaacattca tttttgccac cttttatcat tgcccctatg
    45961 tgtatagtac gggttaagaa aatccgcaat aatactcatt ctgaagatgg ataagggcaa
    46021 gttgctgttt gatgattttt tctcaaactg gtgaaaaaac ttgatgcacg tcaaaaaatg
    46081 acgcatattt gcgcgcgttt tattcatctg gctggacgcc cgtacatgtc tctctatcaa
    46141 cacatgcttg ttttttatgc ggttatggca gcaatcgcat ttcttatcac ctggtttctt
    46201 tctcacgata agaaacgcat ccgtttctta agcgcctttc tggtgggggc aacatggccg
    46261 atgagtttcc cggtggcgct gttgttttca ctgttttaaa tcttactcac tggcttgacg
    46321 gcaccacgca gacttatatc atttggatga atcgataaat ttcacaagtg gctaaggaga
    46381 aagtatgtcg catctggatg aagtcatcgc gcgcgtggat gccgcgattg aagagagcgt
    46441 cattgcccat atgaacgaat tattaatcgc cctgagcgat gacgcggagt taagtcggga
    46501 agatcgctac acccagcagc aacgtctgcg cacagcgatc gcccatcacg gtcgcaagca
    46561 taaagaagat atggaagcgc gccacgaaca gttaaccaaa ggcggcacca tcctctgatt
    46621 aaaatgagcg tctggctacc aaccaggcgc caaccacaag taaaattgcg ccacaaattg
    46681 ggccgaacaa cgcccgtagt ggtacgccat gactgcggaa gatatccagc atcagaccgc
    46741 caatcagctg actggcgacc agtacagcaa tagttgtcgc cgctcccaca ttctgatatc
    46801 cgctgatact ggcgaagaca aaaaacgatc ccagcaagcc aggtataagt gtccaccagc
    46861 gcacgctgga caccagttcg ccaaaccccg ccatgccttg tttaaaccat aaaatagaaa
    46921 caaagagcac aatccccacc agtgagttca gcaacatggc gatgagaatg gtagaggagg
    46981 tctgggtgat gcgcaccatc agcgtgttct ggacaaccag accaattccg gcggcaatca
    47041 aaaaagcaag ggtgagcgac tgattcatcc aatcgcgtcc ggttcagtgc gctcgtcgag
    47101 ttgcaactgc ataaatgtca gatccagcca acgaccaaat ttagtgccta cctgcggcat
    47161 ttgcgcggtg acgacaaatc ccagcgactg gtggagatgc agcgaggcct gattttgcga
    47221 ttcgatcccg gcgaccatga catgcttccc gcaatcccgc gcttcatcaa tcaatcggct
    47281 taacaattta cgccccagac ctttgccctg atgatcggga tggacataaa ccgaatgttc
    47341 cacggtatgg cgaaaaccat cgaaactacg ccagtcgcca aacgaggcat atcccgtcac
    47401 tacgccgttt tcctcgctca ccagcactgg ataacctgct aaagtccgcg cttcaaacca
    47461 ggcaatgcgg ttatcagcat ccaccgtttg gtcattccag atagccgccg tatacaacac
    47521 ggcgtggtta taaatttccg caatggcagc acagtcggct ttgcgggcaa aacggatgga
    47581 catgtctggc ctcaataaaa taatgatgat gatgttatca atactatcga aaacagcccg
    47641 aagcaacgga ttcctcgatg aaattattgc gtgttgcaga ggggatgtga cggctgcaaa
    47701 caaaaccaat cccgtgagcc tgctactatt gatggattca tgccaaaagc acaggagagc
    47761 attatggggc aacaaaagca gcgtaatcga cgttgggttc tggcctcgcg tccacatggc
    47821 gcacctgttc cggagaattt ccgtcttgaa gaagatgatg tcgccacacc gggtgaagga
    47881 caggtgttac tgcgcacagt ttatttgtcc ctggacccgt atatgcgtgg acgtatgagc
    47941 gatgagccat cttattcacc gcctgttgat attggcggcg tgatggtcgg cggtacggtg
    48001 agccgtgtcg tggagtcgaa tcatcctgat tatcagtctg gcgactgggt gctgggctac
    48061 agtggatggc aagactatga catatccagt ggtgatgatc tggtgaaact tggcgatcat
    48121 ccgcaaaatc catcgtggtc gctgggtgtg ctagggatgc caggctttac cgcttatatg
    48181 ggcctactgg atatcggtca gcctaaagag ggcgaaacgt tggtggtagc tgcggcgaca
    48241 ggaccagtgg gggcgacggt ggggcaaatc ggcaaactta aaggttgcag agtggtgggg
    48301 gtagccggtg gcgcggaaaa atgccgccat gctaccgagg tgttaggctt cgatgtttgt
    48361 cttgatcacc acgcggatga ttttgccgaa caactggcga aagcgtgccc aaaaggtatt
    48421 gatatctatt atgaaaacgt gggcggtaag gtattcgatg cggtgctacc gttacttaat
    48481 acatctgcgc gcattcccgt ctgcggatta gtgagcagct ataacgctac agagctacca
    48541 cccggtccgg atcgtttacc tctgttgatg gctacagtgc tgaaaaaacg tattcgcttg
    48601 caaggtttta ttatcgctca ggattatggt caccgcatcc atgagtttca gagggagatg
    48661 gggcaatggg tgaaagagga taaaatccac taccgcgaag aaattactga cggtttagag
    48721 aatgcgccac agacgtttat cggcctgctg aagggtaaaa acttcggcaa agtggtgatc
    48781 cgcgtggcgg gtgatgatta aagtttcaac ggcggcgtaa gccgccataa aaatccaggc
    48841 aaaaagctta ttttcagctt taattaacta accacatcat tgttctgctg ctaataacaa
    48901 caaaggtgag tggtttatga ttattcactt taatacacca ggtgaattcc ttctgccatg
    48961 caggcagggt tggacagaaa acacgcgaag gaattaaaat gcctggaacg ggaaaaatga
    49021 aacatgtcag tttgactctg caggttgaga acgacctgaa acatcagctt agtattggcg
    49081 cattaaaacc tggcgcacgc ctgattacta aaaatctggc ggagcaatta ggtatgagta
    49141 ttacacctgt gcgtgaagca ttattacgtc tggtttcggt gaatgcgctt tctgtcgcac
    49201 ctgcacaagc atttacagtt ccggaagtgg ggaaacgtca attagacgaa atcaatcgga
    49261 tccgctacga actggaatta atggcagttg ctctggctgt tgaaaacctc accccgcaag
    49321 atcttgcgga actccaggaa ttgctcgaga aattacagca ggcgcaagaa aagggcgaca
    49381 tggaacaaat cattaatgta aacaggctat ttcgcttagc gatttatcat cgctcaaata
    49441 tgcccatcct gtgtgagatg attgagcaac tgtgggtcag gatggggcct ggtttacatt
    49501 atctctatga agcgattaat ccagcggaat tacgggagca tatagaaaac tatcatctgt
    49561 tactcgctgc gttaaaagca aaagacaaag agggatgcag acattgtctt gctgaaatta
    49621 tgcaacaaaa tattgctatt ttataccagc aatacaatcg ttaaagtaaa tgcccggcaa
    49681 ataccgggca tcaaggtaat tactcaaatc tccacgcaat attcatgccg acaccataat
    49741 ttcgtccggg cgaaggttcg taatatcgcc cgtttgactc attgacaatg acagaaccaa
    49801 cgtattcttt atcgaataaa ttatcgacac gaccaaataa atccacagtt aaattgtggt
    49861 aattgtattt atacccggtg aataagccga cgagagtata agacggcgct tttgccgtat
    49921 tttcatcatc tgccataata tcgcccatat aacgcgcttc cgtgcctgca taccaaccat
    49981 cttccggtac ataacctatc gacgcaaagc ccatattacg ggcgatccct ggcatccgat
    50041 taccgttaca atcctgttca ttgcaaacat tgctgcgata ggtcgcatca agccaggtcc
    50101 aggacgcgtt tacgcgaaaa tctcctgcga aacgttgatc ccatgccagt tcagcgcctt
    50161 gacgacgggt ctttccggca tttttgtaag tcgtacgccc accgctactg ctatcgacaa
    50221 caatttcatc atcagtgtcg gtctgaaaca atgcgagact aagcagccca tcaccaatac
    50281 gcgttttact gccgatctca attgtatcgt tggtggatgg ttttaaacct aagttcatac
    50341 cgctttgccc atcagcacga taagacagct cattaatcgt cggcgtttca aaacctcgcc
    50401 cggctgccag atagatattc caggcatcgg tcattgcata ttttaacgaa ccggcaggta
    50461 gccatttatg ataactggca tcaccgctgt catcgccgtt acccggagta acgtaatggt
    50521 cgttggaatc aaaccacacg gagctgtagc gcacgccagc atccagcgac agtttttcgc
    50581 tcagctgcca ctgcgtctgt aaatagggat cgatgttcca catcagattg cgttcgtcgc
    50641 gacgcaactc acctttttgc ccgtactccg gcatgccgct attcaggcgg aagttattgt
    50701 agcccttgcg gttttcactc atgttttcgt agttcaggcc ggtagtgaac gtgaccggaa
    50761 cgcccagttc accacggtgt gtccagcggc tgtctattcc ctggtaatgg cgttgcaggg
    50821 taatcacgcc gcccgcatgt gacgggttaa gttgtggtgc catgggtatt gactggtact
    50881 gggtcgtttc tcgctctccg gcatacatca tcacactcat atcatcccgc gaactcaggc
    50941 tacgctcata gcgcaaccca gcctgagttt gcttgatggt ttttcgcgtg tcgtactgtt
    51001 ctgcacgagg cgcttgttgt ggattagcct tccattctgc tttggttagc ccacctgggt
    51061 catctgcttt gatatccaca ctattgaaaa tcagacttaa tttgctggct tcatcaatgc
    51121 gtacgcccag tttggcattg gctaaatttt tctgtgcgcc actatggtca cgatagccgt
    51181 gggtcgtaaa acgcgtggtt gagacggtgt aatcgacatc gccaggctgt gtgccgtctc
    51241 ccgttgcgcc cgttgctttc agcccatagc gccagctgcc aaaactgccg tagtaactac
    51301 tggcttcaat ggttggtggc tgttgtccgg tctgggtggt gacattcatt accccaccag
    51361 acgcgttgcc atacagggca gagaaggggc cacgcagcac ttccacattt tgcacactgc
    51421 ttaaatcgat gttggatgtt tgcccttgcc cgtcgggcat ggtggcggga ataccgtcca
    51481 catacaggcg aataccgcga ataccgtaag tggagcggga gccaaatccg cgaatcgaca
    51541 gctgtaaatc ttgcgcatag ttctgccggt tttgtacctg caaaccaggc acgccggtca
    51601 gtgattcgga caagttaatg cgcggtgttg ccaggcgcat ctcctcgcca tccaccacgc
    51661 ttactgctgc tggggtatcc agttctgaaa ccacctgcgg tgcggcactg acaatcatag
    51721 tctgttcatc agcggcaaaa acaacggggg aaaggacaag cagtgcgggc aaaacggtct
    51781 gtcggacgga aaaaatcttc atgaaaaaag ccaggttaag aatgggaaaa cgccgtcatg
    51841 gtaatgaaat tgtaaattta tggaaaatga aacggcacaa tacgttaagt aattgagaaa
    51901 attgtagtcg taacggcaag aaatgctcca catttgagaa aataatgatt accattccca
    51961 tttataacaa gagcgtaacg atgattacgc ttagcgaagc attgtgaagc agcaaaaata
    52021 tcggttcatc aaagggagtc gtcatgcatt tacgtcatct gttttcatcg cgcctgcgtg
    52081 gttcattact gttaggttca ttgcttgttg tttcatcatt cagtacgcag gccgcagaag
    52141 aaatgctgcg taaagcggta ggtaaaggtg cctacgaaat ggcttatagc cagcaagaaa
    52201 acgcgctgtg gctcgccact tcgcaaagcc gcaaactgga taaaggtggc gtggtttatc
    52261 gtcttgatcc ggtcactctg gaagtgacgc aggcgatcca taacgatctc aagccgtttg
    52321 gtgccaccat caataacacg actcagacgt tgtggtttgg taacaccgta aacagcgcgg
    52381 tcacggcgat agatgccaaa acgggcgaag tgaaaggccg tctggtgctg gatgatcgta
    52441 agcgcacgga agaggtgcgc ccgctgcaac cgcgtgagct ggtagctgac gatgccacga
    52501 acaccgttta catcagtggt attggtaaag agagcgtgat ttgggtcgtt gatggcggga
    52561 atatcaaact gaaaaccgcc atccagaaca ccggtaaaat gagtaccggt ctggcgctgg
    52621 atagcgaagg caaacgtctt tacaccacta acgctgacgg cgaattgatt accatcgaca
    52681 ccgccgacaa taaaatcctc agccgtaaaa agctgctgga tgacggcaaa gagcacttct
    52741 ttatcaacat tagccttgat accgccaggc agcgtgcatt tatcaccgat tctaaagccg
    52801 cagaagtgtt agtggtcgat acccgtaatg gcaatattct ggcgaaggtt gcggcaccgg
    52861 aatcactggc tgtgctgttt aaccccgcgc gtaatgaagc ctacgtaacg catcgtcagg
    52921 caggtaaagt cagtgtgatt gacgcgaaaa gctataaagt ggtgaaaacg ttcgatacgc
    52981 cgactcatcc aaacagcctg gcgctgtctg ccgatggcaa aacgctgtat gtcagtgtga
    53041 aacaaaaatc cactaaacag caggaagcta cccagccaga cgatgtgatt cgtattgcgc
    53101 tgtaatagat atggcgaggg tgaaaacggt gagacttgcc tgccttttat cacggcgtat
    53161 ccggcacttt cgtcagtaat ctgaatttgc ccggcacgta gccgggcaat tttgcaatta
    53221 actcgccgtt tcaggcttaa acacaatttc ctgtttttct tcatcttcct cgacgactgg
    53281 cgcagtgctg tgaatttcag caacgcgttt gcgcacacca aaccagccta taaccagcaa
    53341 aataccgata atcggcagcg ccgcgatagt ataagtcccg ttcgggtaat cgaacgccat
    53401 cagcacaagg acactcagta aaaacagtaa tgtcagccag gaagtgaagg gcgcgccagg
    53461 cagtttaaaa ctgacatccg ctgctttgcc ttctttaatc gctttacgca ggcgcatctg
    53521 gcacacgatg ataaacgccc atgaagcgat gattcccagc gacgcgaagt tcaacacaat
    53581 ctcaaatacg cgcgacggca ccagatagtt gaggaatacg ccgacgacat acacaactag
    53641 tgtcgccaga atcccggcat acggcacatg ctgacgactc attttcgcca taaaactcgg
    53701 tgcggaaccg cccatcgcca ttgagcgcag aatacgtccg gtgcagtaca gacctgaatt
    53761 caggctggag agggcagcgg tcagcaccac aatgttcata atgctgccga tatatggcac
    53821 acccagttta gagaaaaacg tcacgaacgg actttgcccc gcctgatacg cgctccacgg
    53881 caataacata accagcaaca ccacggagcc gacgtaaaac aggccaatac gccaaatcac
    53941 actgttaatg gctttaggca ccatggtctg cggatcttta cattctccgg cagctgtacc
    54001 caccatttca atggaggcaa aagcaaacac tacgccctga atcaacacca gcgcaggcag
    54061 caaaccgtgg gggaagaagc cgccattatc ggtgattaaa tgaaagccag tggtgttgcc
    54121 atccagcggc tgaccactac cgaggaacac tgtacccacg accaaaaagg tcacaatggc
    54181 gagcacttta ataagcgcaa accagaactc catctccgca aaccatttca caccgatcat
    54241 attcatggtg ccaacgatgg taagtgcagc gagcgcaaag acccactgcg gcacgccgcc
    54301 aaacgcaccc cagtaatgca tatacagagc gacggcggta atatcaacaa tccccgtcat
    54361 cgcccagttg atgaagtaca tccagccagc aacataagcg gctttctcac ccaaaaactc
    54421 acgggcataa gaaacaaaac tgccactgga agggcggtgt agcaccagct cacccaatgc
    54481 acgcagaata aaaaacgaaa acaagccaca aattaaataa accagtgcca gtgcgggccc
    54541 cgccatttgc agtcgggctc ctgcacctaa aaacaagccg gtgccaatcg cgccgccaat
    54601 ggcgatcatc tgcacctggc gattgcccat cgctttgtga tacccctctt cgtgggcatt
    54661 aagccagcgg cgtttcgcgg cgtgttgatc tgaagtgtcg gtgtcgtgtt tactcattgc
    54721 tctccctgat tgctttaatg aaaaagtcat ataagttgcc atgaacaatg tttattcatc
    54781 ctggcgatga tagttatcac cattattctt tatgggtata aaactatcgg cgcagcatcc
    54841 tacccgttat cgataaacga tgcaaaacat ccccttacaa tcctgaaggg gattaataca
    54901 actgacgaaa aaatgacaaa tccttttgct ggttaacctg tgtactgtcc tacacttaat
    54961 ctttaaaaga ttgtgagggg catatgatta aggtgtatgg cgtacccgga tggggctcta
    55021 caatcagtga gctgatgcta acactggctg atattcctta tcagttcgtt gatgtcagtg
    55081 gttttgacca cgagggagct tcacgcgagt tattgaaaac cctgaacccg ttgtgtcagg
    55141 ttccgacact ggcattggaa aatgacgaga ttatgacgga gacagcggcg attgcattga
    55201 tggttctcga tcgtcgcccg gaccttgcgc caccggttgg gcgcgccgaa cgtcagctgt
    55261 ttcaacggct attggtctgg ctggttgcta atgtctatcc aacattcact ttcgccgatt
    55321 accctgagcg ttgggctcct gacgcacctg aacagttaaa gaagaatgtt attgaatatc
    55381 gaaaatcgct ttatatctgg ttgaattcgc agctcactgc tgaaccttat gcgtttggtg
    55441 agcaactaac gctggtggac tgttatcttt gcactatgcg cacatggggg cctgggcatg
    55501 aatggtttca ggataatgcc acgaatatca gtgcgattgc tgatgctgta tgtcagttac
    55561 cgaaattaca agaagtatta aaaaggaatg aaattatt
//
LOCUS       DAPHKZ010000016        55580 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.016, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000016 DAPHKZ010000000
VERSION     DAPHKZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 55580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55580
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.016"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(128..1497)
                     /locus_tag="RH288_001035"
     CDS             complement(join(128..1017,1017..1497))
                     /locus_tag="RH288_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS150 family transposase"
                     /protein_id="HDV4030122.1"
                     /translation="MSKPKYPFEKRLEVVNHYFTTDDGYRIISARFGVPRTQVRTWVA
                     LYEKHGEKGLIPKPKGVSADPELRIKVVKAVIEQHMSLNQAAAHFMLAGSGSVARWLK
                     VYEERGEAGLRALKIGTKRNIAISVDPEKAASALELSKDRRIEDLERQVRFLETRLMY
                     PKKAESLSSSHEKVKVLNELRQFYPLDELLRAAEIPRSTFYYHLKALSKPDKYADVKK
                     RISEIYHENRGRYGYRRVTLSLHREGKQINHKAVQRLMGTLSLKAAIKVKRYRSYRGE
                     VGQTAPNVLQRDFKATRPNEKWVTDVTEFAVNGRKLYLSPVIDLFNNEVISYSLSERP
                     VMNMVENMLDQAFKKLNPHEHPVLHSDQGWQYRMRRYQNILKEHGIKQSMSRKGNCLD
                     NAVVECFFGTLKSECFYLDEFSNISELKDAVTEYIEYYNSRRISLKLKGLTPIEYRNQ
                     TYMPRV"
     gene            1577..1729
                     /gene="hokA"
                     /locus_tag="RH288_001036"
     CDS             1577..1729
                     /gene="hokA"
                     /locus_tag="RH288_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokA"
                     /protein_id="HDV4030123.1"
                     /translation="MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFL
                     ACKLKE"
     gene            complement(1916..2128)
                     /gene="cspA"
                     /locus_tag="RH288_001037"
     CDS             complement(1916..2128)
                     /gene="cspA"
                     /locus_tag="RH288_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HDV4030124.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(2409..2699)
                     /locus_tag="RH288_001038"
     CDS             complement(2409..2699)
                     /locus_tag="RH288_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HDV4030125.1"
                     /translation="MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKG
                     TGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME"
     gene            3133..3843
                     /locus_tag="RH288_001039"
     CDS             3133..3843
                     /locus_tag="RH288_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HDV4030126.1"
                     /translation="MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNT
                     VMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQSDDLKPVFDQAFTKVVTTP
                     ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLP
                     AQHQAFNQAWTTAVTATQ"
     gene            complement(3893..4867)
                     /gene="ghrB"
                     /locus_tag="RH288_001040"
     CDS             complement(3893..4867)
                     /gene="ghrB"
                     /locus_tag="RH288_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418009.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HDV4030127.1"
                     /translation="MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFA
                     EAEGLLGSNENVNAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTET
                     VADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLF
                     GAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLS
                     MANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD"
     gene            complement(4971..5630)
                     /locus_tag="RH288_001041"
     CDS             complement(4971..5630)
                     /locus_tag="RH288_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HDV4030128.1"
                     /translation="MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGGHDL
                     NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSP
                     L"
     gene            5783..8116
                     /gene="bisC"
                     /locus_tag="RH288_001042"
     CDS             5783..8116
                     /gene="bisC"
                     /locus_tag="RH288_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418007.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin sulfoxide reductase"
                     /protein_id="HDV4030129.1"
                     /translation="MANSSSRYSVLTAAHWGPMLVETDGETVFSSRGALATGMENSLQ
                     SAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQDEFVRVSWDEALDLIHQQHKRIR
                     EAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKL
                     ICIDPMRSETVDFFGDKMEWVAPHMGTDVALMLGIAHTLVENGWHDEAFLARCTTGYA
                     VFASYLLGESDGIAKTAEWAAEICGVGAAKIRELAAIFHQNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRSAVLSSMQGSLPGGCDAVDK
                     IPVARIVEALENPGGAYQHNGMNRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSFERNDLTMTGDYSNQHLVPMKQVVPPRYEARNDF
                     DVFAELSERWEKGGYARFTEGKSELQWLETFYNVARQRGASQQVELPPFAEFWQANQL
                     IEMPENPDSERFIRFADFCRDPLAHPLKTASGKIEIFSQRIADYGYPDCPGHPMWLEP
                     DEWQGNAEPEQLQVLSAHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQERGIQD
                     GDTVRLWNARGQILAGAVISEGIKPGVICIHEGAWPDLDLTADGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALAWLEKYNGPELTLTAFEPPASS"
     gene            complement(8085..8525)
                     /locus_tag="RH288_001043"
     CDS             complement(8085..8525)
                     /locus_tag="RH288_001043"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV4030130.1"
                     /translation="MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAY
                     LANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRHPHLML
                     EVYQKNQPAINFYQAQGFHIVDCAWQDETQLPTWIMSWPVVQTL"
     gene            complement(8522..9085)
                     /gene="tag"
                     /locus_tag="RH288_001044"
     CDS             complement(8522..9085)
                     /gene="tag"
                     /locus_tag="RH288_001044"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDV4030131.1"
                     /translation="MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY
                     LQMEQNGEPFVDFVWSFVNHQPQVTQATTLSEIPTSTSASDALSKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHVVGCCCYPGNKP"
     gene            9243..9942
                     /locus_tag="RH288_001045"
                     /pseudo
     CDS             9243..9942
                     /locus_tag="RH288_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418004.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            10171..11379
                     /locus_tag="RH288_001046"
     CDS             10171..11379
                     /locus_tag="RH288_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4030132.1"
                     /translation="MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAP
                     VSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSDNLMML
                     WLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTQLLE
                     TVGLEKTFVIWGAIALLMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWM
                     LAVMFLTACMSGLYVIGVAKDIAQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDK
                     IARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFG
                     LNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQ
                     KMLREAHGSL"
     gene            11703..13394
                     /gene="eptB"
                     /locus_tag="RH288_001047"
     CDS             11703..13394
                     /gene="eptB"
                     /locus_tag="RH288_001047"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HDV4030133.1"
                     /translation="MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWK
                     GISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
                     LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAW
                     ARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     AQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDL
                     YAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLI
                     ILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVID
                     QVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPANAQ
                     AFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAKEAAAN"
     gene            13486..13562
                     /locus_tag="RH288_001048"
     tRNA            13486..13562
                     /locus_tag="RH288_001048"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13520..13522,aa:Pro,seq:cgg)
     gene            14305..15912
                     /gene="dppA"
                     /locus_tag="RH288_001049"
     CDS             14305..15912
                     /gene="dppA"
                     /locus_tag="RH288_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter substrate-binding
                     protein DppA"
                     /protein_id="HDV4030134.1"
                     /translation="MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWH
                     DNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
                     NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY
                     QKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA
                     KNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV
                     FEPVRKEVKGYVVDPLGKHHFENVSIE"
     gene            16220..17239
                     /gene="dppB"
                     /locus_tag="RH288_001050"
     CDS             16220..17239
                     /gene="dppB"
                     /locus_tag="RH288_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HDV4030135.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLEL
                     GVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            17249..18151
                     /gene="dppC"
                     /locus_tag="RH288_001051"
     CDS             17249..18151
                     /gene="dppC"
                     /locus_tag="RH288_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HDV4030136.1"
                     /translation="MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLF
                     IAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSL
                     LVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            18162..19145
                     /gene="dppD"
                     /locus_tag="RH288_001052"
     CDS             18162..19145
                     /gene="dppD"
                     /locus_tag="RH288_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDV4030137.1"
                     /translation="MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPG
                     KYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLDDAGRPTL"
     gene            19142..20146
                     /gene="dppF"
                     /locus_tag="RH288_001053"
     CDS             19142..20146
                     /gene="dppF"
                     /locus_tag="RH288_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HDV4030138.1"
                     /translation="MSTQEATLQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMIEMPTGGELYYQGQDLLKHDPQAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLSGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKDYGGQLVACFAVDQDENPQR
                     "
     gene            complement(20176..21447)
                     /locus_tag="RH288_001054"
     CDS             complement(20176..21447)
                     /locus_tag="RH288_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HDV4030139.1"
                     /translation="MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGL
                     KGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYF
                     LMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
                     KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQ
                     VLNPMNIAYRKREADKVLATRLALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAF
                     EQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRII
                     DTKKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKV
                     AQLEKLRGFKAWLILLYGILLCLSPLLKLIE"
     gene            21923..22030
                     /gene="ldrD"
                     /locus_tag="RH288_001055"
     CDS             21923..22030
                     /gene="ldrD"
                     /locus_tag="RH288_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxic polypeptide
                     LdrD"
                     /protein_id="HDV4030140.1"
                     /translation="MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
     gene            complement(22117..23796)
                     /gene="bcsG"
                     /locus_tag="RH288_001056"
     CDS             complement(22117..23796)
                     /gene="bcsG"
                     /locus_tag="RH288_001056"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HDV4030141.1"
                     /translation="MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFAAFLLMPLPRYSLHRLRHWIALPIGFALFWHDTRLPGPESIMSQGSQVAGFS
                     TDYLIDLVTRFINWQMIGAIFVLLVAWLFLSQWIRITVFVVAILLWLNVLTLVGPSFS
                     LWPAGQPTTTVTTTGGNAAATVAATGGAPVVGDMPAQTAPPTTANLNAWLNNFYNAEA
                     KRKSTFPSSLPADAQPFELLVINICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATS
                     YSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQHLMMGHNGQFGGFLK
                     EVRENGGMQSELMDQTNLPVILLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNT
                     LPLHDGNHYPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQVSGLRDIPSPSITDVPVGVKFFGMKAPHQGAPIVIEQPSSFLAISDLVVRVLDGK
                     IFTEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ"
     gene            complement(23793..23984)
                     /gene="bcsF"
                     /locus_tag="RH288_001057"
     CDS             complement(23793..23984)
                     /gene="bcsF"
                     /locus_tag="RH288_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HDV4030142.1"
                     /translation="MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPR
                     YVKPAGTLRRTEKARATKK"
     gene            complement(23981..25552)
                     /gene="bcsE"
                     /locus_tag="RH288_001058"
     CDS             complement(23981..25552)
                     /gene="bcsE"
                     /locus_tag="RH288_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HDV4030143.1"
                     /translation="MRDIVDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLAN
                     QTIASQAETAHVAVISMDSDPAKIFQLDDSQGPEKIKLFSMLNHEKGLYYLTRDLQCS
                     IDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINPGNNNDKQFSL
                     LLEEYRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGIWTLVQSEEAE
                     IQPRSDEKRILSNVAVLEGAPPLSEHWQLFNNNEVLFNEARTAQAATVVFSLQQNAQI
                     EPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTM
                     IESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGV
                     LVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLP
                     TGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGMPLPLTQSSKPVINAEHDGRHWRRI
                     PEPMRLLDDAVERSS"
     gene            25825..26013
                     /locus_tag="RH288_001059"
     CDS             25825..26013
                     /locus_tag="RH288_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhjR family protein"
                     /protein_id="HDV4030144.1"
                     /translation="MNNNEPDTLPDPAIGYIFQNDIVALKQAFSLPDIDYADISQREQ
                     LAAALKRWPLLAEFAQQK"
     gene            26025..26777
                     /gene="bcsQ"
                     /locus_tag="RH288_001060"
     CDS             26025..26777
                     /gene="bcsQ"
                     /locus_tag="RH288_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
                     /protein_id="HDV4030145.1"
                     /translation="MAVLGLQGVRGGVGTTTITAALAWSLQMLGENVLVVDACPDNLL
                     RLSFNVDFTHRQGWARAMLDGQDWRDAGLRYTSQLDLLPFGQLSIEEQENPQHWQTRL
                     SDICSGLQQLKASGRYQWILIDLPRDASQITHQLLSLCDHSLAIVNVDANCHIRLHQQ
                     ALPDGAHILINDFRIGSQVQDDIYQLWLQSQRRLLPMLIHRDEAMAECLAAKQPVGEY
                     RSDALAAEEILTLANWCLLNYSGLKTPVGSAS"
     gene            26774..29392
                     /gene="bcsA"
                     /locus_tag="RH288_001061"
     CDS             26774..29392
                     /gene="bcsA"
                     /locus_tag="RH288_001061"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HDV4030146.1"
                     /translation="MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILA
                     WIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGASRKETPKPR
                     RRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSL
                     ILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIART
                     THEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFV
                     LPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYFYGPPTEMLTVVVSMVWVFYNLIVL
                     GGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQIL
                     EGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWAL
                     WQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRP
                     ERSETAQPSDQALAQQ"
     gene            29403..31742
                     /gene="bcsB"
                     /locus_tag="RH288_001062"
     CDS             29403..31742
                     /gene="bcsB"
                     /locus_tag="RH288_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDV4030147.1"
                     /translation="MKRKLFWICAVAMGMSAFPSFMTQATPATQPLINAEPAVAAQTE
                     QNPQVGQVMPGVQGADAPVVAQNGPSRDVKLTFAQIAPPPGSMVLRGINPNGSIEFGM
                     RSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPIN
                     PLFITDFNRVRLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPV
                     PFFDPRDNRTNTLPMVFAGAPDVGLQQASAIVASWFGSRSGWRGQNFPVLYNQLPDRN
                     AIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAKGIAQ
                     GNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAI
                     NVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEAN
                     RLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMNPMPGGSVDNCITFQPVQN
                     HVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKAPNEAQMET
                     LLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIIGGIPDKLKDDKQIDLLVQAT
                     ESWVKTPMRQTPFPGIVPDESDRAAETRSTLTSSGAMAAVIGFQSPYNDQRSVIALLA
                     DSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGYLPWFERVWYAL
                     ANHPILLAVLAAISVILLAWVLWRLLRIISRRRLNPDNE"
     gene            31749..32855
                     /gene="bcsZ"
                     /locus_tag="RH288_001063"
     CDS             31749..32855
                     /gene="bcsZ"
                     /locus_tag="RH288_001063"
                     /EC_number="3.2.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
                     /protein_id="HDV4030148.1"
                     /translation="MNVLRSGIVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVID
                     PSDARKITTSEGQSYGMFSALAANDRAAFDNILDWTQNNLAQGSLKERLPAWLWGKKE
                     NSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLG
                     SMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFS
                     PDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTE
                     KNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNY
                     VLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH"
     gene            32837..36310
                     /gene="bcsC"
                     /locus_tag="RH288_001064"
     CDS             32837..36310
                     /gene="bcsC"
                     /locus_tag="RH288_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026226.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
                     /protein_id="HDV4030149.1"
                     /translation="MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHRE
                     DLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSR
                     TTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIP
                     ARRGEAINQLKRINADAPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGAS
                     KIWYGQIKDMPVSDASVSALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQG
                     LAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDP
                     HSSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLG
                     DVAMARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRR
                     SIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQA
                     GQRSQADTLMRNLAQQKSNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQE
                     LVNRLQSDQVLETANRLRESGKEAEAEAMLRQQPPSTRIDLTLADWAQQRRDYTAARA
                     AYQNVLTREPANADAILGLTEVDIAAGDKAAARSQLAKLPATDNASLNTQRRVALAQA
                     QLGDTAAAQRTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPTQALETYKDAMVA
                     SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGT
                     GGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDC
                     SGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAH
                     RRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTG
                     KNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEY
                     LSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDG
                     GSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGWQGDMDL
                     PPQPLIPYADW"
     gene            36392..38380
                     /gene="hmsP"
                     /locus_tag="RH288_001065"
     CDS             36392..38380
                     /gene="hmsP"
                     /locus_tag="RH288_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HDV4030150.1"
                     /translation="MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIP
                     ERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLV
                     TIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIIT
                     CETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHA
                     ITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGK
                     NQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQ
                     QPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQL
                     MHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDF
                     GMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVE
                     TEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK"
     gene            38563..39849
                     /gene="dctA"
                     /locus_tag="RH288_001066"
     CDS             38563..39849
                     /gene="dctA"
                     /locus_tag="RH288_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HDV4030151.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPG
                     AGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQ
                     LGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLI
                     VLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS"
     gene            40070..41566
                     /locus_tag="RH288_001067"
     CDS             40070..41566
                     /locus_tag="RH288_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDV4030152.1"
                     /translation="MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQW
                     QVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHAIPRIALTQSGGLDAAQARSLWQ
                     QGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
                     QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAM
                     TLLVVGNVDARSVVDQINKTFGELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKDIGLGFDCRVLYLRA
                     QCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARA
                     DTDILMGQRMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILL
                     QPKGEPEFNMKALQAVWDQIMAPSTAAATTSVATDDVHPEVTDIPPAQ"
     gene            complement(41662..42591)
                     /gene="kdgK"
                     /locus_tag="RH288_001068"
     CDS             complement(41662..42591)
                     /gene="kdgK"
                     /locus_tag="RH288_001068"
                     /EC_number="2.7.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygluconokinase"
                     /protein_id="HDV4030153.1"
                     /translation="MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
                     ALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYY
                     WRNEAAAKFWLESEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
                     GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTH
                     NAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSAEDAAKRGHLTASTVIQYRGAIIPREAMPA"
     gene            42823..43590
                     /gene="pdeH"
                     /locus_tag="RH288_001069"
     CDS             42823..43590
                     /gene="pdeH"
                     /locus_tag="RH288_001069"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HDV4030154.1"
                     /translation="MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRL
                     MAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLA
                     SVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
                     GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVE
                     TPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL"
     gene            43660..45720
                     /locus_tag="RH288_001070"
     CDS             43660..45720
                     /locus_tag="RH288_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDV4030155.1"
                     /translation="MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSA
                     ELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLEKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLPFSEVTGSKGKADKEKVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGG
                     VDLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGD
                     SDIHGSLVYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKS
                     VQPAGKVLPYDRFETDKWDVMDADVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQP
                     LKFGMAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAE
                     LRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNC
                     AAANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILS
                     QMKK"
     gene            complement(45902..47224)
                     /locus_tag="RH288_001071"
     CDS             complement(45902..47224)
                     /locus_tag="RH288_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HDV4030156.1"
                     /translation="MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATA
                     AVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIGSAVFGHFGDRVGRKATLVASLL
                     TMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHESPVFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFST
                     AAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASI
                     LGASVAPYIAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL"
     gene            complement(47635..48648)
                     /gene="yhjD"
                     /locus_tag="RH288_001072"
     CDS             complement(47635..48648)
                     /gene="yhjD"
                     /locus_tag="RH288_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HDV4030157.1"
                     /translation="MTQENEIKRPIQDLEHEPIKPLDNSEKGSKVSQALETVTTTAEK
                     VQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPML
                     LQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
                     RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALH
                     LNSIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVI
                     KIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGK
                     TQP"
     gene            complement(48697..49596)
                     /locus_tag="RH288_001073"
     CDS             complement(48697..49596)
                     /locus_tag="RH288_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417978.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4030158.1"
                     /translation="MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQL
                     GTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPPGI
                     AKSLLLPRLSEFLYLHPGIELELSSHDRPVDILHDGFDCVIRTGALPEDGVIARPLGK
                     LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGG
                     MLTVNSSENYLTAGLAGLGIIQIPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQR
                     RELSRRVNLFMQWLAGVMKEYLD"
     gene            50116..50718
                     /locus_tag="RH288_001074"
     CDS             50116..50718
                     /locus_tag="RH288_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDV4030159.1"
                     /translation="MQIVMFDRQSIFIHGMKISLQQRIPGVSIQGASQADELWQKLES
                     YPEALVMLDGDQDGEFCYWLLQKTVVQFPEVKVLITATDCNKRWLQEVIHFNVLAIVP
                     RDSTVETFALAVNSAAMGMMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNK
                     EIGRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS"
     gene            complement(50769..52418)
                     /locus_tag="RH288_001075"
     CDS             complement(50769..52418)
                     /locus_tag="RH288_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HDV4030160.1"
                     /translation="MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     TGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRY
                     LWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGIL
                     ASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKLI
                     EKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            52822..54219
                     /gene="ccp"
                     /locus_tag="RH288_001076"
     CDS             52822..54219
                     /gene="ccp"
                     /locus_tag="RH288_001076"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HDV4030161.1"
                     /translation="MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAV
                     SENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQLMDYDIKLGYKSFNLEAVRAAL
                     LADKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
                     SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSW
                     DEIIAKLEKDPQLKTQFLEVYPQGFSGENITDAIAEFEKTLITPDSPFDKWLRGDENA
                     LTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKE
                     ERDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFL
                     HSLNGVYTPYMQDKQ"
     gene            54430..>55580
                     /locus_tag="RH288_001077"
     CDS             54430..>55580
                     /locus_tag="RH288_001077"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDV4030162.1"
                     /translation="MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCG
                     PVQICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYE
                     FPQPLHDALDKFQADTGIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHK
                     FGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRL
                     GREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLK"
BASE COUNT        13319 a        13889 c        14874 g        13498 t
ORIGIN      
        1 cttattaagc tagaatagcc acgggtgctt gagactgttt gtctcaggta ttcaccgaaa
       61 ggcagacaga gaaaagcccc acctgactat aaatcaaagt ttgtactgac cccaaaaagt
      121 tggacagtta aacacgaggc atataggtct gattccgata ttcaattgga gtcagacctt
      181 ttaatttcag gctaattctt ctgctgttgt agtattcaat atattccgta acagcatcct
      241 tcagttcgct tatattactg aactcatcaa gataaaaaca ctccgacttt aaggttccaa
      301 agaaacactc caccacagca ttatccagac aattgccttt tctggacatg ctttgtttaa
      361 taccatgttc tttaaggata ttttgatatc ttctcatacg atactgccat ccctggtcag
      421 agtgcagaac aggatgctcg tgaggattaa gctttttgaa tgcctgatcg agcatattct
      481 caaccatgtt catcactggt ctttccgaaa ggctgtaaga aataacttcg ttgttgaaga
      541 gatctattac tggagacaaa tacagcttgc gcccattgac tgcaaattca gtaacatcgg
      601 taacccactt ctcgtttggc cgcgtagcct tgaaatctct ttggagaaca ttaggggcgg
      661 tttgccctac ctctcctctg taagagcggt atcgcttgac cttaatcgct gctttaagtg
      721 agagggttcc catcaggcgc tgaacagctt tatggttaat ctgtttccct tctcgatgaa
      781 gagacagcgt taccctacgg tatccgtatc ggcctctatt ctcgtgataa atctcactaa
      841 tacgcttttt aacgtccgca tacttgtcag gcttgctgag agcctttaga tgataataaa
      901 acgtactgcg cggtatctcc gcagccctga gaagctcatc aagaggataa aactgcctta
      961 gctcgttgag tactttcact ttttcgtggg atgagctaag gctttcagct tttttagata
     1021 cataagccgc gtttcaagaa atcgaacttg cctttcaaga tcctcaatgc gtcggtcttt
     1081 tgacagctcc aatgctgatg ccgctttttc tggatcaact gatattgcaa tgtttctttt
     1141 ggtgccaatc ttgagcgcgc gtaaaccagc ttctccgcgc tcttcataga ccttcagcca
     1201 cctggctaca gaaccactac cagcaagcat aaagtgagca gcagcctgat taagggacat
     1261 gtgctgctcg atcacagctt tcacgacctt aatacgcaac tctggatcag cactaacgcc
     1321 tttaggtttg ggaattaaac ctttttctcc atgtttttca tagagggcaa cccatgtcct
     1381 gacctgggtt cgggggacac caaaacgtgc cgagatgatc ctgtaaccat catcagttgt
     1441 gaagtagtga ttcacgactt caaggcgctt ttcaaaaggg tattttggct ttgacatatt
     1501 aggggctatt ccatttcatc gtccaacaaa atgggtgcag tacatactcg ttggaaatta
     1561 acacaggagg ctgggaatgc cgcagaaata tagattactt tctttaatag tgatttgttt
     1621 cacgctttta tttttcacct ggatgataag agattcactg tgtgaattgc atattaaaca
     1681 ggagagttat gagctggcgg cgtttttagc ctgcaaattg aaagagtaag agtcttcggc
     1741 gggaaattat tcccgcctta cttacggcgt tgcgcattct cattgcaccc aaatttattc
     1801 ttcacaaaaa taataataga ttttattacg cgatcgatta tttatttcct gaaaacaaat
     1861 aaaaaaatcc ccgccaaatg gcagggatct tagattctgt gcttttaagc agagattaca
     1921 ggctggttac gttaccagct gccgggcctt tagcgccgct ttcgatggtg aaggacactt
     1981 tctgaccttc gtccagagat ttgtaaccat cgttctggat agcagagaag tgtacgaaca
     2041 catctttaga gccatcgtca ggagtgatga agccgaagcc tttgtcagcg ttgaaccatt
     2101 ttacgatacc agtcatttta ccggacatag tgtattacct ttaataatta agtgtgcctt
     2161 tcggcgatat ggcgtgcttt acagattttg aagcgttaaa ggaatgtgca ctacgagggg
     2221 tatcaacgat aactcttgaa gggacttgcc ttactacact gctttaatgg tctgtacgtc
     2281 aaaccgttga tgtgcattaa gccacgcatt ggcgggtgat gcaacaatta tttttcatat
     2341 ttatgattaa tcggttggaa aacggtcctg tcatcaggac cgtaaacagc aataaagtgg
     2401 ataaaagtct attccatcaa ctgcttactt aatgccgggt tggcttgaat caaacgcatc
     2461 aattttagtt cggcacttga aggcttcacg cgtctggatt cccattcctt taccatggcg
     2521 actgatacgc ccaaaacccg ggcgaaatca tcgattttta atcctgtccc ttttcgtaac
     2581 tgctcaattt cggtacagga cgttgttctg tgcgtcaggg taattttctg cgtttcatct
     2641 ttaaaaacaa tctgttccag gctgctcaac agctcatgca ttggatcttt atattccatt
     2701 gaaaactcct caaatcacac tgcgggatcg tgaattgcat cgaagctcat taagaatagt
     2761 cgggaaaagc agacacagcg gggtgaagtc agggcatgct ctggctatga ttcgattcag
     2821 cctgtcattt agcgtgactt atagccacct aacgatctga taaatgccga tatatctctt
     2881 accactcctg ttttgtaaag atttcgaaaa tctaaccttc tgcgaaggcg taaatctctg
     2941 gctacaaaaa aggcaacggc actatcattt tttaacaatg aaacaacaaa ttaaccttgt
     3001 ttcattttct ccatgatttt accaggaaga ttacgtagaa agggtatcct gcaagcctgt
     3061 cctggactat ccttgtcacg tcagacacgc gtgtgtcgtt gtgcgctttt tttgggtgaa
     3121 aggagtaaga aaatggcgac aggaaagtcc tgctctcgct ggtttgcgcc tcttgcggcg
     3181 ttattaatgg tagttagcct gagtgggtgt tttgataaag aaggcgatca gcgtaaagcg
     3241 tttatcgact tcctgcagaa tacagtgatg cgtagcggtg aacgtctacc aaccctgact
     3301 gccgatcaga aaaaacagtt tggtcctttt gtctctgatt acgcgattct gtatggttat
     3361 tctcagcagg tgaatcaggc gatggattcc ggtctgcgcc cggttgtaga cagcgttaac
     3421 gcaattcgcg taccgcagga ttacgttacg caaagcggtc cgctgcgtga aatgaacggt
     3481 tcgctgggtg tgctggcgca acaactgcaa aatgcgaagt tgcaggccga tgctgcgcac
     3541 tctgcgctaa aacagagcga tgatttgaaa ccggtctttg atcaggcatt caccaaagtg
     3601 gtaacgacgc cagctgatgc attgcaaccg ttgattccgg cggcacaaac tttcacgcaa
     3661 caactggtga tggttggaga ctacattgct cagcaaggta ctcaggtgag ctttgtcgca
     3721 aatggcatcc agttcccgac ttcacagcag gcaagtgaat ataacaaact gattgcgcca
     3781 ttaccggcac agcatcaggc gtttaatcag gcctggacta cagcagttac tgcaacccaa
     3841 taaagagtaa aagcccgagc gattatcggg ctttactcta cgcagtcgcg gcttagtccg
     3901 cgacgtgcgg attcacacag ttcttctcaa cctttccttg taacgcatca atcaaattat
     3961 ccacggcaca ggcggccatg ccataacgcg tctcatgggt ggcagatcca atatgcggta
     4021 ctgcgacgac gttggccatt gagagcaacg gcgaatctac ggacagtggc tcttgctcga
     4081 agacatccag cccggcagcg tgaatttcgc ctttctgcaa tgctgcgatc agtgcatttt
     4141 cgtcaaccac cgggccacgt ccggcattaa tgaaaatggc ggaggatttc attttggcga
     4201 attgttctgc gccaaacaga tgatgcgtct catcagttaa cggcaggatc aggcaaacga
     4261 aatctgactc ttgtaacaga gtatccaaat cgcagtagcg ggcgttgaag cgttcttctg
     4321 cttctttatg gtggcggcgc gcgttataga ggatgggcat gttgaagcca aagtgcgcac
     4381 gttgtgccag cgccatgccg atccgtccca tcccgacaat gcccagtgtt ttatggtgaa
     4441 cgtcagtgcc gtaccagtcc gggcctatgc tcgcggtcca ttcgcctgct tttacccgtt
     4501 ctgctacctc cacaacccga cgagcggtag acaacaccag cgccatcagc gtatcggcga
     4561 cggtttctgt taatacggtt ggcgtgtgca tcagcagaat ttttcgggcg gtaagcgcat
     4621 cgacatcaaa attgtcatag ccgacggaga tcgttgatgt ggcacgcagt ttcggcattt
     4681 tttccagcaa tgcggcattt acattctcgt ttgaacccag taaaccttca gcttcggcaa
     4741 aaattgctgc attttgttcg acggtttgtg ggctgaggtt tgccacctgg tgaacggtga
     4801 aatgctcttg caggcgttgc agtaaatcat caggtaaggc tttgtagagg ataacggacg
     4861 gcttcatgct tctctccatt cactgataag gcgatcacct tagcctgaaa tatgatgaag
     4921 gaaaactgaa gaatgccagg tgatttctgc atcacctggc atgaaaggga ttacagcggg
     4981 cttaaggtaa tttctacacg gcggttttgc gccttacctt ctgcggtgct gttgctggcg
     5041 attgggttag ccgggccaag gccctgagta cggatgcggc tggcgtccac gccctgggtg
     5101 atcaacgcgc tggcaacgga atccgcacgt tgctgggaga gacgcatgtt caggtcgtga
     5161 ccacccgtgc tgtcggtata accaatcacg ttaaccgccg ttttcggata ctctttcagt
     5221 accattgcca cgccggtcag ggtgttagcg cccgccggtt tcagggtcgc gctgctgctg
     5281 tcgaaggtca cattgttcgg catattgagg ataatgttat ccccgctgcg ggttacgcta
     5341 acaccagtgc cgcgcatttt gtcgcgcagc ttcgcttcct gcacatccat gtaataacca
     5401 acgccgccgc ccagagctgc gcctgctgct gcgccaatca gcgcgccttt accgcgatct
     5461 ttcttcgaag aagagagcgc accaataccc gcgcccacga gagagcccag acctgcgccg
     5521 atagcagatt tacctgcttc gcgttcgccg gtgtaagggt tagttgtgca gccagatacc
     5581 gccagagcgc cactcactac ggcggcaata agataaacac gtttcttcat tgttaatcct
     5641 taataacctt tttattcttt gccacgggtt ccgtggcggg agattatgcc gcgtgaacat
     5701 gaagattatt cctgggaata ctcggaaatt tgtaagtaat atttaactgc tcaatacatc
     5761 taacctttca ggagtcttcg gtttggccaa ctcatcctca cgatattccg ttctgactgc
     5821 cgcccattgg gggcccatgc tggttgaaac cgacggcgaa accgtgttta gctcgcgtgg
     5881 cgcgttagcc acaggaatgg aaaactcctt gcagagcgcg gttcgcgacc aggttcacag
     5941 caatacgcgg gtacgatttc caatggtgcg aaaaggcttt cttgcgtcac cggaaaaccc
     6001 gcaaggcatt cgtgggcagg atgaatttgt tcgcgtgagt tgggatgagg cgctggatct
     6061 tattcaccaa caacataaac gcattcgtga ggcttatggt ccggcatcga tttttgctgg
     6121 ttcctacggc tggcgttcaa acggcgtgct gcataaggcc tcgacattat tacaacgcta
     6181 tatggcgctg gcaggcggtt ataccgggca tctgggggat tattcgaccg gcgcggcaca
     6241 ggcgatcatg ccgtatgtcg tgggtggtag tgaagtttat caacagcaga ccagttggcc
     6301 gctggtgctg gaacatagcg atgtcgtggt gctgtggagt gctaacccac tcaatacgct
     6361 gaaaattgcg tggaatgcat ccgatgagca ggggctttct tacttttctg cactgcgtga
     6421 cagcgggaaa aagctgatct gcattgatcc aatgcgatcg gaaaccgtcg atttctttgg
     6481 cgataaaatg gagtgggtgg caccgcacat gggcaccgat gttgcgctga tgctggggat
     6541 cgcccatacg ctggtggaaa atggttggca cgacgaagcg tttctggcgc gttgcaccac
     6601 aggttatgcc gtcttcgcct cttatttgct gggcgagagt gacggaatag cgaaaaccgc
     6661 cgaatgggca gcagagattt gtggtgttgg cgcagcgaaa atccgcgagc tggcggctat
     6721 tttccaccaa aataccacca tgctgatggc aggctgggga atgcagcgcc aacagtttgg
     6781 tgagcaaaaa cactggatga tcgtcacgct ggcagcaatg ttggggcaaa tcggcacacc
     6841 cggcggcggt tttggtcttt cttaccattt tgccaatggt ggtaacccca cgcggcgttc
     6901 tgcggtgctc tcttccatgc agggcagctt gccgggtggc tgcgatgcgg tggataaaat
     6961 ccctgttgcc cgcattgttg aagcactgga aaaccctggt ggcgcatatc aacacaacgg
     7021 tatgaaccga catttcccgg atattcgttt tatctggtgg gcgggcggtg ccaactttac
     7081 tcatcatcag gataccaatc gcctgatccg tgcctggcaa aaaccggagc tggtggtgat
     7141 ctctgaatgc ttctggacgg cggcggcaaa acacgcggat atcgttctgc ctgcgactac
     7201 ctcttttgag cgtaatgatc tcaccatgac cggtgattac agtaatcagc atctggtgcc
     7261 gatgaagcaa gtggtgccgc cacgctatga agcgcgtaat gattttgatg tttttgccga
     7321 gttaagtgaa cgctgggaga agggcggtta tgcacgtttt acggaaggaa aaagtgagct
     7381 gcaatggctg gaaacgtttt ataacgttgc ccgacagcgc ggggcaagcc agcaggttga
     7441 attgccgcca tttgctgagt tctggcaagc caaccagtta attgagatgc cggaaaaccc
     7501 ggacagcgag cggtttattc gcttcgctga tttttgccgc gatccgctgg cgcatccgtt
     7561 aaaaaccgcc agcggcaaga ttgaaatctt ctcacagcgt attgccgatt acggttaccc
     7621 ggattgccct gggcatccaa tgtggctgga gccggacgaa tggcagggca atgccgaacc
     7681 agaacagttg caggtacttt ctgcccatcc ggcgcaccgc ctgcacagcc agctgaatta
     7741 cagttctctg cgcgaattgt acgcggtggc aaatcgtgag cctgtcacca ttcatcctga
     7801 cgatgcccag gagcgcggca tacaagatgg cgatactgtt cggttgtgga acgcacgcgg
     7861 gcaaattctt gccggagcgg tcattagcga gggaattaaa cctggcgtga tttgcattca
     7921 cgaaggggca tggccggatc tggatttaac cgctgacggt atttgtaaaa acggcgcagt
     7981 gaacgtgctg accaaagatc tccccagctc gcggctgggg aatggctgtg cgggtaatac
     8041 ggcgctggca tggctggaaa aatacaacgg tccggaactg acacttacag cgtttgaacc
     8101 accggccagc tcataatcca tgtgggtagt tgggtttcat cctgccatgc gcaatcgaca
     8161 atgtgaaaac cctgtgcctg gtaaaaattt atcgccggtt gatttttttg ataaacctcc
     8221 agcatcaggt ggggatggcg ctgctgcaca tactgcatca gcgccttacc aataccgcgc
     8281 ctgacggcct tcggtgcgac aaacatcgct gccagaaatc ggccttccat aatgctgaca
     8341 aaaccgagaa gcttaccgtc ttcttcccag acccagtttt gcgcgttggc aagataggca
     8401 tcccgcacca gcggaatgca gtcacgccag taattcgctt ttataaaggg atgcccccag
     8461 gttgtacttt ccagccacag ttcgaggatc gcggggagtt ctgaacgttg cgcttcccga
     8521 atcatggttt atttcccgga tagcaacagc agccaaccac atgatcattc accagcccac
     8581 atgcctgcat aaaggagtaa cagattgtgg tgccgacaaa cttaaaacca cgttttttca
     8641 gtgccttaga tagggcgtcg gaggcggacg tagatgtggg aatttcgctc aacgttgtgg
     8701 cttgtgtcac ctgtggctga tgatttacaa acgaccagac aaagtcgaca aacggttcgc
     8761 cgttctgttc catttgcagg tacgcccgcg cattaccaat aattgcctga attttccctc
     8821 gatggcggat aatcccggcg tcctgtacca gtctttcgac atcctcttcc tgcattgctg
     8881 cgaccttcac cggatcgaac tgatgaaagc aggcgcgata gttttcgcgt tttttgagga
     8941 cggtgatcca cgataatcca gcctgctgcc cttcaaggca gatcatttcg aacagttttt
     9001 tactgtcagt ttcaggcacg ccccactcat tatcatggta ggcaatataa agcgggtcct
     9061 gactcaccca gccgcaacgt tccatacttt ccctcgctat gtacccgatc gtaaaaattt
     9121 cagccgcttt tcttgacgca tcggtgaaaa agtcaatatt taatacaggg ctactatgcc
     9181 cgatatcctt catacaatga caataatatt gccgaattcg gctcttccct ggagtcgtgt
     9241 taatgatcat aaaaaaaagc ggtggtcgct ggcagctaag cctgctggcg agcgtggtaa
     9301 tcagtgcctt ttttctcaac acagcttacg cctggcaaca agaatatatc gttgatacgc
     9361 aacccggact ttccacagag cgttacacct gggatagtga tcatcaacct gattacaacg
     9421 atattttgtc gcaacgtatt caaagtagcc aaagggcgct gggactggaa gtcaatctgg
     9481 cggaagaaac cccctgtgga tgtgaccagc agtatgagta tgggctggaa ttttccttta
     9541 tatgaacagg ttacaaccgg cccggtcgcg gcattacatt acgatggcac aaccacctcg
     9601 atgtataacg agtttggcga cagtactacc acgctgaccg atccgttatg gcatgccagc
     9661 gtgagtacct taggctggcg tgttgactcc cggcttggcg atctccgacc ctgggcgcaa
     9721 atcagctata accagcaatt tggcgagaat atctggaagg cgcaatcagg cctgagccgg
     9781 atgacggcga caaaccagaa cggcaactgg ctggatgtca ccgtaggcgc tgatatgttg
     9841 ctcaatcaaa atattgccgc ctatgccgcg ctaactcagg cagaaaatac cactaataat
     9901 agcgactatc tgtatacgat gggggttagc gccagatttt aacgtaacag tcacaattga
     9961 aaccattaaa taacaatagt tgtggcgata gtgggtgcta acttaccaaa taataaattt
    10021 ggtgaataat tgtcgcgtca ttcattcctg aactaaggca tttcattccg ttctgatggc
    10081 atttcatgcc gtttttcccc aggcataaag tgcacttcgt tatggttgtc ggcagagatt
    10141 tttccttttt attactgcag gaatactgcc atgacacctt caaattatca gcgtacccgc
    10201 tggctgacac tcatcggtac tatcattacc cagtttgcgc tggggtcggt ttatacctgg
    10261 agcctgttta atggcgcgct ttccgccaag ctggatgcgc cggtaagcca ggtcgctttc
    10321 tctttcggct tgttaagtct ggggctggca atttcgtctt ctgttgcggg caaattacag
    10381 gaacgttttg gcgttaaacg cgtcaccatg gcttccggca ttttgctggg attaggcttc
    10441 ttcctgacag cgcattctga caacctgatg atgctgtggt taagcgccgg tgtgctggtg
    10501 ggactggcag atggcgcggg ttatctgctg acgctctcta actgtgtgaa gtggttcccg
    10561 gagcgtaaag gtctgatctc cgcgttcgct atcggttctt atggtctggg tagcctgggt
    10621 ttcaaattta tcgacacgca gctgctggaa acggtcggtc tggaaaaaac ctttgtgatt
    10681 tggggagcga ttgcgctgtt gatgattgtt ttcggcgcaa cgttaatgaa agacgcacca
    10741 aaacaggaag tgaaaaccag caatggtgtg gtggagaaag attacacgct ggcagagtcg
    10801 atgcgtaaac cgcagtactg gatgttagcg gtaatgttcc tgaccgcctg catgagcggc
    10861 ctgtacgtga ttggggtagc gaaagatatc gcccaaagtc tggcacacct tgatgtggtt
    10921 tccgcagcca atgcagtcac tgttatttcc atcgccaacc tttcaggtcg tctggtgctg
    10981 ggtattctgt ctgacaaaat cgcccgtatc cgtgttatta ccattggtca ggtgatatcg
    11041 ctggtgggta tggcggccct gctgtttgca ccattgaatg cagtgacgtt ctttgcagcg
    11101 attgcctgcg tggcatttaa ctttggcggc actattaccg tctttccgtc actggtcagt
    11161 gagttctttg gcctcaataa cctggcgaaa aactacggtg tgatttatct cggtttcggt
    11221 atcggtagca tttgtggttc gattatcgcc tcactgtttg gcggcttcta tgtgaccttc
    11281 tacgtgattt tcgccctgct gattctgtca ttggcgcttt ctacgacgat tcgtcagcca
    11341 gagcagaaaa tgttgcgtga ggcgcatggc tccctttaat gctcagccgc gagctactgg
    11401 gcttcagctt ccgtgtgcat caaacgcatc aacgaaatgt ataaacaatg actcgtaaaa
    11461 tttgggccaa ttaactggcc ctttttactg ctttttgtaa cgctaaagtc tcttttcaaa
    11521 cttgcatttt tgtaaatttg tgcttcatgc acactctttc cccacacttt ttccctttgc
    11581 tgtggtctac ttattcgcgc gtgtagattt tacttatctg actacctccg cactttttcc
    11641 ctgccgggcc tgaaaagcca ctaagcaggg tgttatcacc tgtttgtcca gggtttgttt
    11701 gcatgagata catcaaatcg attacacagc agaagctgag ctttttgctt gcaatctata
    11761 ttggcctttt tatgaatggc gcggtttttt accgccgctt cggcagctat gcgcacgatt
    11821 ttaccgtctg gaaaggcatt tctgctgttg ttgaactggc cgccaccgta ctggtgacct
    11881 tctttttact acgtcttctt tcgctgtttg gccgccgcag ctggcgtatt ctggcatcgc
    11941 tggtggtgct cttttccgca ggtgccagct attacatgac cttccttaat gtggtcattg
    12001 gttatggcat catcgcttcc gtcatgacca ccgatatcga cctgtcaaaa gaagttgttg
    12061 gtctgaactt tattctctgg ttaatcgccg ttagtgcatt gcctcttatc cttatctgga
    12121 ataaccgctg tcgctacacc ttgctccgac aactgcgaac cccagggcag cgtattcgca
    12181 gcctggcggt cgtcgtactg gcgggtatta tggtttgggc accgattcgt ttgctggata
    12241 tccagcagaa gaaagtggag agggcgaccg gcgttgattt gccgagttat ggcggtgtcg
    12301 tagcgaactc ttatctgcca tcaaactggc tttctgcgtt ggggctgtat gcctgggcgc
    12361 gggtcgatga atcttccgat aataattcat tgcttaatcc ggcgaagaaa ttcacttatc
    12421 aggcaccgca aaacgttgat gacacttatg tcgtgtttat catcggtgaa accacgcgtt
    12481 gggaccatat gggtattttc ggctatgagc gtaataccac gccgaaactg gcccaggaga
    12541 aaaatctggc ggcgttccgt ggttactcct gtgataccgc aaccaaactc tcactgcgtt
    12601 gcatgtttgt acgtcagggg ggcgcggaag ataatccgca gcgcacatta aaagaacaga
    12661 acattttcgc ggttctgaag cagttaggat tcagttctga cctctacgct atgcagagcg
    12721 aaatgtggtt ctacagcaac acgatggcgg acaacattgc ttatcgtgag cagattggtg
    12781 cggagccacg taatcgtggc aagccggtag atgatatgtt gctggtagac gaaatgcagc
    12841 aatcgctagg gcgcaacccg gatggtaagc atctgatcat tctgcatacc aaaggttcgc
    12901 attttaacta cacccagcgt tatccgcgta gcttcgcgca gtggaagccg gaatgtattg
    12961 gtgttgatag cggctgtacc aaagcgcaga tgatcaactc ctatgacaac tcggtgacct
    13021 atgtggatca ctttatctcc agcgtgattg atcaggttcg cgataagaaa gcgattgtgt
    13081 tctacgcagc tgaccacggt gagtcaatta atgaacgcga gcacctgcac ggcacgccgc
    13141 gtgaactggc accgccggag cagttccgcg taccgatgat ggtctggatg tcagataaat
    13201 atctggaaaa tccggccaat gcgcaggcgt ttgcgcagct gaaaaaagaa gccgacatga
    13261 aagtgccacg ccgtcacgta gagctgtacg ataccatcat gggttgtctt ggctatactt
    13321 caccggatgg tggaattaac gaaaacaaca actggtgtca catcccgcag gcaaaagagg
    13381 cagcggctaa ctaagcggcc tgctgacttt ctcgccgatc aaaaggcatt ttgctattaa
    13441 gggattgacg agggcgtatc tgcgcagtaa gatgcgcccc gcattcggtg attggcgcag
    13501 cctggtagcg cacttcgttc gggacgaagg ggtcggaggt tcgaatcctc tatcaccgac
    13561 caaattcgaa aagcctgctc aacgagcagg cttttttgca tctgcagctc atgaggatga
    13621 gaacctccgg gggcagggag gttcgactcg acgtaggcct gataagacgc gtcagcgtcg
    13681 catcaggcaa atgtgccggc cattgtcgga tgcggcgcga ccgccttatt cgacctacac
    13741 gacacacatt tccctgccaa atttgcgccc catatctcac tatccattaa cggatttgtg
    13801 acagaaacca ttgtcttttt ttatatttgc ttaaatcttt ttttgcgtta cttatggctg
    13861 gccctggcat tttccgctgt gcgttttagc gttcatggta ttaatcgctc agatatccac
    13921 cttttcctca gatttttttc attaaatgca taaaacttaa tcaccaaatg ttgctaaata
    13981 ttaagctgat tgttctggtc atgttggagt agcacaaatt tctctgctgc aaatagctgt
    14041 ttgaagtttt tttaatcttt gtttgtggat tctcaccgtt ggtgtaaatc ccggttggct
    14101 gtattgacgt tttcacattc tgttgacaga ttgtaggtca cgaggggcat tttatggagg
    14161 atccgcactg ttacactgat gttaattagt acggcatccc cacctcataa cgttgacccg
    14221 accgggcaaa aaacaaaaaa ggtcaggcag cgacaaccca ctgcaaaggg ttaaaacaac
    14281 aaacatcaca attggagcag aataatgcgt atttccttga aaaagtcagg gatgctgaag
    14341 cttggtctca gcctggtggc tatgaccgtc gcagcaagtg ttcaggctaa aactctggtt
    14401 tattgctcag aaggatctcc ggaagggttt aacccgcagc tgtttacctc cggcaccacc
    14461 tatgacgcct cttccgtccc gctttataac cgtctggttg aatttaaaat cggcaccacc
    14521 gaagtgatcc cgggcctcgc tgaaaagtgg gaagtcagcg aagacggtaa aacctatacc
    14581 ttccatctgc gtaaaggtgt gaagtggcac gacaataaag aattcaaacc gacgcgtgaa
    14641 ctgaacgccg atgatgtggt gttctcgttc gatcgtcaga aaaacgcgca aaacccgtac
    14701 cataaagttt ctggcggcag ctacgaatac ttcgaaggca tgggcttgcc agagctgatc
    14761 agtgaagtga aaaaggtgga cgacaacacc gttcagtttg tgctgactcg cccggaagcg
    14821 ccgttcctcg ctgacctggc aatggacttc gcctctattc tgtcaaaaga atatgctgat
    14881 gcgatgatga aagccggtac accggaaaaa ctggacctca acccaatcgg aaccggtccg
    14941 ttccagttac agcagtatca aaaagattcc cgtatccgct acaaagcgtt tgatggctac
    15001 tggggcacca aaccgcagat cgatacgctg gttttctcta ttacccctga cgcttccgtg
    15061 cgttacgcga aattgcagaa gaatgaatgc caggtgatgc cgtacccgaa cccggcagat
    15121 atcgctcgca tgaagcagga taaatccatc aatctgatgg aaatgccggg gctgaacgtc
    15181 ggttatctct cgtataacgt gcagaaaaaa ccactcgatg acgtgaaagt tcgccaggct
    15241 ctgacctacg cggtgaacaa agacgcgatc atcaaagcgg tttatcaggg cgcgggcgta
    15301 tcagcgaaaa acctgatccc gccaaccatg tggggctata acgacgacgt tcaggactac
    15361 acctacgatc ctgaaaaagc gaaagccttg ctgaaagaag cgggtctgga aaaaggtttc
    15421 tccatcgacc tgtgggcgat gccggtacaa cgtccgtata acccgaacgc tcgccgcatg
    15481 gcggagatga ttcaggcaga ctgggcgaaa gtcggcgtgc aggccaaaat tgtcacctac
    15541 gaatggggtg agtacctcaa gcgtgcgaaa gatggcgagc accagacggt aatgatgggc
    15601 tggactggcg ataacgggga tccggataac ttcttcgcca ccctgttcag ctgcgccgcc
    15661 tctgaacaag gctccaacta ctcaaaatgg tgctacaaac cgtttgaaga tctgattcaa
    15721 ccggcgcgtg ctaccgacga ccacaataaa cgcgttgaac tgtacaaaca agcgcaggtg
    15781 gtgatgcacg atcaggctcc ggcactgatc atcgctcact ccaccgtgtt tgaaccggta
    15841 cgtaaagaag ttaaaggcta tgtggttgat ccattaggca aacatcactt cgaaaacgtc
    15901 tctatcgaat aattaaaagc catacaagac tgatggcaaa ggcaaaaatg cctgatgcgc
    15961 tccgcttatc aggcctacga aaattctgca atgtattgaa tttgcacgat tttgtaggcc
    16021 ggataaggcg ttaacgccgc atccggcata aacaaagcgc actttgtcaa caatctgtat
    16081 acccggtggc gctgtgcctc tgcgtgcagc gccatccggc agcaatactt cattccctgt
    16141 ccgataaggg cgggaattga tttgtgagca atacagacac gcagttccag gctgcgggtc
    16201 actatagaga atccgggtta tgttgcagtt tattctccga cgtttgggac ttgtcatccc
    16261 cacgtttatc ggtattaccc ttctcacatt tgcctttgtc cacatgatcc cgggcgatcc
    16321 ggtgatgatc atggcgggcg aacgtgggat ctccccagag cgtcacgcgc agctgctggc
    16381 tgaactcggc ttagataaac cgatgtggca gcagtatctc cattacattt ggggcgttat
    16441 gcatggcgat ctaggcattt caatgaaaag ccgcatcccg gtttgggaag agttcgtgcc
    16501 gcgcttccag gccacgctgg aacttggcgt ctgcgcgatg atttttgcta cggcagtcgg
    16561 tattccggtc ggcgtgctgg ctgcggttaa acgcggttcc attttcgatc acacagcggt
    16621 tggcctggcg ctgacaggtt attcaatgcc tatcttctgg tggggcatga tgctgatcat
    16681 gctggtttcg gtgcactgga acctgacgcc cgtctccggt cgcgtgagcg atatggtgtt
    16741 cctcgatgac tccaatccgt taaccggttt tatgctaatc gacaccgcca tctggggtga
    16801 agacggcaac tttatcgatg ccgtcgccca tatgatcttg cctgccattg tgctgggtac
    16861 tattccgctg gcggtcattg tgcgtatgac acgctcctcg atgctggaag tgctgggcga
    16921 ggattacatc cgcaccgcgc gcgccaaagg gctaacccgc atgcgggtga ttatcgtcca
    16981 tgcgctgcgt aacgcgatgc tgccggtggt gaccgttatc ggcctgcagg tgggaacatt
    17041 gctggcgggg gcgattctga ccgaaaccat cttctcgtgg cccggtctgg gacgctggtt
    17101 gattgacgca ctgcaacgcc gcgactatcc ggtagtgcag ggcggcgtat tgctggtggc
    17161 gacgatgatt atcctcgtca acttgctggt cgatctgctg tacggcgtgg tgaacccgcg
    17221 tattcgtcat aagaagtaag gggacatcat gtcacaggtt actgaaaata aagtgattag
    17281 cgcaccggtg ccgatgaccc cgttacagga gttctggcac tattttaaac gcaacaaagg
    17341 cgcggtcgtc gggctggttt acgtcgtcat cgtgctgttc atcgcgatct ttgccaactg
    17401 gattgcaccc tataacccgg cggaacagtt ccgcgatgca ctgctcgccc cgccagcctg
    17461 gcaggaaggc ggcagcatgg cgcacttgct gggcaccgat gacgtaggcc gtgatgtgct
    17521 gtcgcgcctg atgtacggtg cgcgcctgtc gctgctggtt ggctgtctgg tagttgtgtt
    17581 atcgctgatt atgggcgtta ttctcggcct gatcgccggt tactttggcg gcctggtcga
    17641 taacatcatt atgcgcgtgg tcgatatcat gctggcgctg ccaagtctgc tgctggcgct
    17701 ggtgctggtg gcaattttcg gcccgtcgat tggtaacgcc gcgctggcac tgaccttcgt
    17761 tgccttgccg cactatgtgc gcttaacccg cgccgccgtg ctggtggaag ttaaccgcga
    17821 ttacgtcacc gcgtctcgcg tggcgggtgc cggggcgatg cgtcagatgt ttattaacat
    17881 cttcccgaac tgccttgcgc cgctgattgt tcaggcgtcg ctcggtttct ctaacgccat
    17941 tctcgatatg gctgctcttg gtttcctcgg catgggggca cagccgccaa cgcctgagtg
    18001 gggcaccatg ctctccgacg tgttgcagtt cgcgcaaagc gcctggtggg tcgtgacctt
    18061 cccgggtctg gcgatcctgc tgacggtgct ggcatttaac ctgatgggtg acggtctgcg
    18121 tgacgcgctc gatcccaaac tgaagcagta agaggttcga gatggcgtta ttaaatgtag
    18181 ataaattatc ggtgcatttc ggcgacgaaa gcgcgccgtt ccgcgccgta gaccgcatca
    18241 gctacagcgt aaaacagggc gaagtggtcg ggattgtggg tgagtccggc tccggtaagt
    18301 cggtcagttc actggcgatt atggggctga ttgattatcc gggccgcgta atggcagaaa
    18361 aactggagtt taacggccag gatttgcagc gtatctcaga aaaagagcgc cgcaacctgg
    18421 tgggtgccga agtggcgatg atcttccagg acccgatgac cagccttaac ccgtgctaca
    18481 ccgtgggttt ccagattatg gaagcgatta aggtgcatca gggcggcaac aaaagtaccc
    18541 gccgtcagcg agcgattgac ctgctgaatc aggtcggtat tcccgatccg gcatcgcgtc
    18601 tggatgttta cccgcatcag ctttccggcg gcatgagcca gcgcgtgatg atcgccatgg
    18661 cgattgcctg tcggccaaaa ctgctgattg ccgatgaacc gaccaccgcg ctggacgtga
    18721 ccattcaggc gcaaatcatc gaactactgc tggagctaca gcagaaagag aacatggcgc
    18781 tggtgttaat tacccatgac ctggcgctgg tggcggaagc ggcacataaa atcatcgtga
    18841 tgtatgcagg ccaggtggtg gaaaccggtg atgcgcacgc catcttccat gcgccgcgtc
    18901 acccgtatac tcaggcattg ctgcgtgcgc tgccagaatt tgctcaggac aaagaacgtc
    18961 tggcgtcgtt gccaggtgtc gttcccggca agtacgaccg cccgaacggc tgcctgctta
    19021 acccgcgctg cccctatgcc actgacagat gtcgcgctga agaaccggcg ctgaatatgc
    19081 tcgctgacgg gcgtcagtcc aaatgccatt acccacttga tgatgccggg aggccgacac
    19141 tatgagtacg caagaggcca ccctgcaaca accgctgttg caggctatcg acctgaaaaa
    19201 acattatccg gtgaagaaag gcatgttcgc gccggaacgt ctggttaaag cgctggatgg
    19261 cgtttcgttt aaccttgaac gtggcaaaac gctggcagta gtgggcgaat ctggctgcgg
    19321 taaatcgacc ctcggtcggt tgctgacgat gattgaaatg cccaccggtg gcgagctgta
    19381 ttaccagggg caggatctgc ttaagcacga tccgcaggcg cagaagctgc gtcggcagaa
    19441 aatccagatc gtcttccaga acccttacgg ttcgctgaat ccgcgtaaaa aagtcgggca
    19501 aattcttgaa gagccgctgc tgatcaacac cagcttaagc aaagaacagc gtcgggaaaa
    19561 agccctgtcg atgatggcga aagtcggcct gaaaaccgag cactatgacc gctatccgca
    19621 tatgttctcc ggcggtcagc gtcagcgtat cgccatcgcc cgtggtctga tgctcgaccc
    19681 ggatgtggtg attgccgatg aaccggtttc cgcgctggat gtttcagtgc gcgcgcaggt
    19741 gctgaatctg atgatggatt tgcagcagga gttggggctg tcttatgtct ttatctccca
    19801 cgacctgtcg gtggtggagc acattgctga tgaagtgatg gtgatgtacc tgggccgctg
    19861 cgtggagaag ggaacgaaag accaaatctt caataacccg cgccatccgt acactcaggc
    19921 gctactttcc gcgacgccgc gcctgaaccc ggacgatcgc cgcgagcgca tcaagctcag
    19981 cggtgaacta ccaagcccac tgaatccacc gccgggttgc gccttcaacg cccgctgtcg
    20041 tcggcgcttc ggcccctgca cccagttgca gccgcagcta aaagactacg gcggtcaact
    20101 ggtagcttgt tttgctgttg atcaggatga aaatccgcag cgttaactca caaaaccggg
    20161 gccatgcgct ccggtttact caatcagctt caacagtggc gacaagcata gcaaaatgcc
    20221 gtacagcaga atcagccagg ctttaaatcc gcgaagtttt tccagttgtg cgactttata
    20281 gatcaggaaa aacggaatga ggcacgacac aataccatat aacgggcttc ccaactgaaa
    20341 gaacaccagc accgatacac gaaacgaaac ccaaatcgtc aacgtaatga cgataaaagc
    20401 gcagatcgcc agagtcagca cgcgtgagtt aattttcttg gtatcaataa ttcggcttaa
    20461 cagattgaga ataatgcctt taatggcctc gtggaaaccg agataaatgc caaagaatgc
    20521 ggtcagtacg gcaaagatat taagcaccgt agaggtgata tgaatgatat gcccagggat
    20581 cacctgcgcg gccagcgcca gtgctgagat attttgttca aaggcagaaa cggcttcttc
    20641 gtggctaatt gagaaggtaa acgaaaaggc aaaaaacagg atcaccgcga tgagcgtgat
    20701 ataactaatt cggtgggtac gcagcgcgag ccgggttgcc agtactttat ccgcttcccg
    20761 tttacgatag gcaatattca ttgggttaag tacctgaata aatactgcag aaaagaagca
    20821 aaatggaatg gtaagcaaga catcgcggaa aaagacggag gcttgcggga aggcggttat
    20881 attggcgaaa ttccagtgcg ggatcatcgc aaaaccgaac acgacaataa tccctacttt
    20941 gaccaccacc attggcccgg aaatcttaaa cagtaatcgt tcaccaccag acgcaatcgc
    21001 caccagtacg gcgaaaatag cgactttata aagtagagat tgtgaaagat cggcatcggt
    21061 taaaccgaag gttttcaggt acgaggcgct gtcgaaaacc acggagagag agtagataaa
    21121 aatcccgtgg ataatcatca aaaagtagat aaccccgagg aaaattcccc agttcttccc
    21181 caggtaatga ctgataatat cggtgtagtc attacaggaa tcgctttcag aaagggtttt
    21241 taaataaatg tcctgcacta cccaggtggc aggataagca atgatcgctg cggtaataaa
    21301 tacccaaatt cccttcaagc caatttgtac tggcatcagc acggttccgg caccaatcgc
    21361 catgcctatg cataataaaa cccagccgaa gtcgtagcgt gtaaacggca atttctgatt
    21421 gtgtttcgat agtgtgttgt gctgcataaa gtcctgtcca gaaagaagtc ggcctcgcaa
    21481 aaatgaataa acccagtttc tcttgcgcaa caggtggaga agtcgaatac gcagtatgta
    21541 aaaaatgagg caacagattc actggggagg tcgcgaggag gcgcaattct acaaaattgc
    21601 gcatttcact accagtctgg agtcagcccg gatatgaact gcaactattg caaataaaga
    21661 aattaagctg gaaggcatcg cgcaatgagg aagattgccg ggtgctgaca gtaaaaagca
    21721 atcgtagaat cagcggcaag ccggaaaggt tccggtgagg cgcaatgttg cgggggcttt
    21781 atccctggtg gcattggttg ctggagagag aaaacccccg cacgttgcag gtatgcacct
    21841 gacaacacca cgggggctaa tcttgactct agaccactca agaatagccg cgaaacgttg
    21901 tcattacaac acaggcggct atatgacgtt cgcagagctg ggcatggcct tctggcatga
    21961 tttagcggct ccggtcattg ctggcattct tgccagtatg atcgtgaact ggctgaacaa
    22021 gcggaagtaa cgtgtcatgc gggcgtcagg ctgccgtaat ggcaatttgc gcccggacca
    22081 ggccgcaggg gggaaactct gcggcctttt tcgttcttac tgcgggtaag gcacccagtc
    22141 gccgccgttc aggcgaacgt acggtttatc ctggtattga ataactactg catttgagtt
    22201 ctcggagacc ggtgctgttt gtggcaaccc actggtgagt tttttccagt caacattgtc
    22261 ttcggtgaaa atcttgccat cgagaacgcg aaccaccaga tcggagatag ccaggaagct
    22321 gctcggttgt tcgatgacaa tcggtgcccc ctgatgcggt gccttcatgc cgaagaattt
    22381 caccccaacg gggacgtcgg tgatagacgg gctagggata tcacgtaggc cagatacctg
    22441 cattctgtcg cccttcagcg cgccgccgtg ttccggcacc acgaccacca tcactttacg
    22501 acccgatttc tcaagttcag taaagaaggc gtccagttca tcaaagaatt tctgcgcccg
    22561 cgctttgtaa tccgctgttt tgctgacccc cggataatgg ttgccgtcat gcagtggaag
    22621 cgtgttgtag aacgtggcac tacggctgtt tttatctttt tcggtaacgt ccagccagcg
    22681 gttaagcaca gcggtatcgt cataaaccgg cgaaccatca aagcccagca aaataaccgg
    22741 cagatttgtt tgatccatca attcgctctg catgccgcca ttttcgcgaa cttctttcaa
    22801 aaaaccgccg aactggccgt tatgtcccat catcaggtgc tgggtaaagc ccagtttcga
    22861 aaggttatca aacagatagc agtcgttatt tgccggttga tacagattag tgtgcgaagt
    22921 ctgcccgcag ctggcgcgca gtaaacggat cgccgccggg ccactgtagg aggtggcgga
    22981 gttaaagttc ttgaactcaa tatcgaaatg cgaccacagt ggatgcgaca tcaacccggc
    23041 ggcttctata tccgaccagg aaagcgaaca gatgttaatc accagtagtt caaatggctg
    23101 agcatcagcg ggcagcgaag acgggaaggt cgatttacgt ttcgcctccg cgttatagaa
    23161 attattcagc caggcgttaa ggttcgccgt tgttggcggt gcagtttgtg cgggcatatc
    23221 acccactacc ggtgcgccac ccgtcgccgc aacggttgcc gctgcgttac cacccgtcgt
    23281 tgttacagtg gtcgtcggtt gtccggctgg ccacaaggag aaacttggtc ccaccagggt
    23341 aagtacgttc agccatagca gtatggcaac cacaaaaacg gtaatgcgaa tccattgtga
    23401 caggaataac caggccacta ataaaacaaa aatggcccca atcatctgcc agttaataaa
    23461 gcgtgtgaca aggtcgatta aataatcggt actgaacccc gccacctgcg aaccctggct
    23521 cattatgctt tccgggccag gcaaccgggt gtcatgccag aacaaagcaa agccgatcgg
    23581 cagggcaatc cagtggcgca agcgatgcag gctgtagcgc ggaaggggca tcagcagaaa
    23641 cgcggcaaac accaaattga ggagcggatg gaagttaaga tatcccgccc acaacaggcc
    23701 gaacttaacc agaaaataga agttccagcc ggaaaggccg cgccagtatt gccagaggga
    23761 agaaggcatg gcggtatttt gcgtaaattg agtcattttt tggttgccct ggctttttcc
    23821 gtgcggcgta acgtcccggc cggtttaaca taacgaggtt tagcaaagaa caaacgtaag
    23881 gtgtcgcgaa tgcgtcgcaa agagtgccgc gccagatagc ccagcgggaa aaatatcagt
    23941 gcgcaaacga caataatttc aatgatatcg ctgatggtca tcatgatgag cgctccacag
    24001 catcatctaa cagtcgcatg ggttctggta ttcgtcgcca gtggcgacca tcgtgctcgg
    24061 cattgatgac cggtttagaa ctttgcgtta aaggcagcgg catgccccat tgttctgggg
    24121 caagcaagcg catctgcacc agctcggcac tgatttgatc atcttcaaac cagaccatac
    24181 ggtttgagaa aatgtcgcca gtaggcaatg ggaaaatatg attcaacgcg gtatccagat
    24241 cgttaatccg acagaatgag agaaacagca ccagccgatt accgccaatg gtcatgatat
    24301 cgccggtacg gttagggcga cacagcgtca gggcttgttc aacgcggata cccggtaccg
    24361 gacgtagggc aaccagaacg cctttaccgt gggcaggtaa tagagggtta ttcatcatgt
    24421 tgttgacggc attacagaac acatcccact tctggaaacc acgcagtttg agcggctggg
    24481 tcattgacag caaggtagtg atatcttccg gcacatagcg actaaacttc tgcccttgca
    24541 cgctttcgat catcgtcaga caacgggaga gtggcgcatt ccacggaata accatatttg
    24601 caccgcaggc caataacaaa cgttcatcgg tggcgcgcag gctagcggta ttttcccgca
    24661 cgaggatttt catcgcacta ccgcgctggc gacgcagggt atgaatgctg cgggccagtg
    24721 gctcgatttg cgcattttgc tgtaaagaaa agaccaccgt cgccgcctga gcggtacggg
    24781 cttcattgaa caggacttcg ttattgttga acagttgcca gtgttccgat agcggcggcg
    24841 caccttccag tacagcaaca ttactcagaa tgcgtttttc gtcgctgcgt ggttggatct
    24901 ccgcctcttc gctttgaact aatgtccaga taccattttg ttgctgaacg ctaagctgct
    24961 gacgggcgct gacccctttt tcgttgcacc agaaggcaat atccagcaaa tgttggtcac
    25021 cctgaaaacg caaactggca agaccaaaaa gtgaacggta ttcctcaagc aacaatgaaa
    25081 attgtttatc gttattattt ccgggattaa ttaccaaaag cgaacaatgg tttaacctgc
    25141 tccatttatt cattttatcc aaccatgagc gaagccgctc ggcaggaatg ttttgccatg
    25201 cgttatttgc gcaaacaaga ataaaaaggt aattatgggg atcaatagaa cactgcaaat
    25261 cacgggtcaa atagtataga cctttttcat gatttagcat tgaaaataat tttatttttt
    25321 ccggcccttg agaatcatct aattgaaaga ttttcgccgg atcgctgtcc atgctaatga
    25381 ccgcgacgtg tgcggtttca gcctgggatg caattgtttg attcgccaga ctgatagcat
    25441 cttcatggcg atcgacgtta aaccaccaga cgccgcctgc tggcatatgt cgcagctcat
    25501 cccataatga tgagataccg atagagaata cagggtccac aatgtccctc atgtcaccat
    25561 tttgtctgat tatcagttta ctagcgaaag ctaagaaata aacctaccat tgaaattaaa
    25621 acttatcaga tttagcatgt gaatcaattt agaaggtcac aagacgtgtg attttagtct
    25681 tttcgttttt aactttttct gttgcgtaac ggaaagtcaa aaagtgagca aattcccgtc
    25741 tcgccgtaaa caataaaccg gcgaaatgct cacggttaga attgtctcat gaacggtacg
    25801 gttatttcat agggatcaag caaaatgaat aacaatgaac cagatactct gcctgatccc
    25861 gcgataggct atatcttcca gaatgatatt gtggcgttaa agcaggcatt ttcactgcct
    25921 gatattgatt atgccgatat ttcccaacgc gaacagttgg ccgcggcatt aaaacgctgg
    25981 ccgttgctgg cagagtttgc gcaacaaaag taggggattg gtgaatggcc gtactgggat
    26041 tgcagggggt gcggggaggc gtggggacaa caaccatcac cgccgcatta gcctggtcat
    26101 tacaaatgtt gggagaaaat gtcctggtgg tcgatgcctg cccggacaac ttgttgcgcc
    26161 tgtcatttaa tgttgatttt acccaccgtc agggctgggc cagagcgatg ctggatggcc
    26221 aggactggcg tgacgctggg ttgcgctaca cctcgcagct cgatttgctg ccttttggtc
    26281 agttatccat tgaagaacaa gaaaatccac agcactggca aacccggctg agcgatattt
    26341 gctccggctt acagcaacta aaagccagcg ggcgttacca gtggatttta atcgacttac
    26401 cgcgtgatgc ctcgcagata acccaccagc tgctgagttt gtgcgatcac tcgctggcaa
    26461 tcgtcaatgt ggatgccaac tgccatatcc gactgcatca gcaagcgctg ccggatggcg
    26521 cacatatttt gattaatgac ttccgtattg gcagtcaggt tcaggacgat atttaccagc
    26581 tttggttgca aagccagcgc cgattactgc cgatgctcat tcatcgtgat gaagcgatgg
    26641 ctgaatgcct ggcggctaag caaccagtag gtgaatatcg cagtgatgcg ctggcggctg
    26701 aagagatact gacgctggcg aactggtgcc tgttgaacta ctccgggctg aaaacgccag
    26761 tcgggagtgc atcatgagta tcctgacccg gtggttgctt atcccgccgg tcaacgcgcg
    26821 gcttatcggg cgttatcgcg attatcgtcg tcacggtgcg tcggctttca gcgcgacgct
    26881 cggctgtttc tggatgatcc tggcctggat ttttattccg ctggagcacc cgcgctggca
    26941 gcgtattcgc gcagaacata aaaacctgta tccgcatatc aacgcctcgc gtccgcgtcc
    27001 gctggacccg gtccgttatc tcattcaaac atgctggtta ttgatcggtg catcgcgcaa
    27061 agaaacgccg aaaccgcgca ggcgggcatt ttcaggtctg caaaatattc gtggacgtta
    27121 ccatcaatgg atgaacgagc tgcctgagcg cgttagccat aaaacacagc atctggatga
    27181 gaaaaaagag ctcggtcatt tgagtgccgg ggcgcggcgg ttgatcctcg gtatcatcgt
    27241 caccttctcg ctgattctgg cgttaatctg cgttactcag ccgtttaacc cgctggcgca
    27301 gtttatcttc ctgatgctgc tgtggggggt agcgctgatc gtacggcgga tgccggggcg
    27361 cttctcggcg ctaatgttga ttgtgctgtc gctgaccgtt tcttgccgtt atatctggtg
    27421 gcgttacacc tctacgctga actgggacga tccggtcagc ctggtgtgcg ggcttattct
    27481 gctcttcgct gaaacgtacg cgtggattgt gctggtgctc ggctacttcc aggtagtatg
    27541 gccgctgaat cgtcagccgg tgccattgcc gaaagatatg tcgctgtggc cgtcggtgga
    27601 tatctttgtc ccgacttaca acgaagatct caacgtggtg aaaaatacca tttacgcctc
    27661 gctgggtatc gactggccga aagataagct gaatatctgg atccttgatg acggcggcag
    27721 ggaagagttt cgccagtttg cgcaaaacgt gggggtgaaa tatatcgccc gcaccactca
    27781 tgaacatgcg aaagcaggca acatcaacaa tgcgctgaaa tatgccaaag gcgagttcgt
    27841 gtcgattttc gactgcgacc acgtaccaac gcgatcgttc ttgcaaatga ccatgggctg
    27901 gttcctgaaa gaaaaacagc tggcgatgat gcagacgccg caccacttct tctcaccgga
    27961 cccgtttgaa cgcaacctgg ggcgtttccg taaaacgccg aacgaaggca cgctgttcta
    28021 tggtctggtg caggatggca acgatatgtg ggacgccact ttcttctgcg gttcctgtgc
    28081 ggtgattcgt cgtaagccgc tggatgaaat tggcggcatt gctgtcgaaa ccgtgactga
    28141 agatgcgcat acttctctgc ggttgcaccg tcgtggctat acctccgcgt atatgcgtat
    28201 tccgcaggcg gcggggctgg cgaccgaaag tctgtcggcg catatcggtc agcgtattcg
    28261 ctgggcgcgc gggatggtac aaatcttccg tctcgataac ccgctcaccg gtaaagggct
    28321 gaagtttgct cagcggctat gttacgtcaa cgccatgttc cacttcttgt cgggcattcc
    28381 acggctgatc ttcctgactg cgccgctggc gttcctgctg cttcatgcct acatcatcta
    28441 tgcgccagcg ttgatgatcg ccctattcgt gctgccgcat atgatccatg ccagcctgac
    28501 caactccaag atccagggca aatatcgcca ctctttctgg agtgaaatct acgaaacggt
    28561 gctggcgtgg tatatcgcac caccgacgct ggtggcgctg attaacccgc acaaaggcaa
    28621 atttaacgtc accgccaaag gtggactggt ggaagaagag tacgtcgact gggtgatctc
    28681 gcggccctac atcttccttg tcctgctcaa cctggtgggc gttgcggtag gcatctggcg
    28741 ctacttctat ggcccgccaa ccgagatgct caccgtggtc gtcagtatgg tgtgggtgtt
    28801 ctacaacctg attgttcttg gcggcgcagt tgcggtatcg gtagaaagca aacaggtacg
    28861 ccgatcgcac cgcgtggaga tgacgatgcc cgcggcaatt gcccgcgaag atggtcacct
    28921 cttctcgtgt accgttcagg atttctccga cggtggtttg gggatcaaga tcaacggtca
    28981 ggcgcagatt ctggaagggc agaaagtgaa tctgttgctt aaacgcggtc agcaggaata
    29041 cgtcttcccg acccaggtgg cgcgcgtgat gggtaatgaa gttgggctga aattaatgcc
    29101 gctcaccacc cagcaacata tcgattttgt gcagtgtacg tttgcccgtg cggatacatg
    29161 ggcgctctgg caggacagct acccggaaga taagccgctg gaaagtctgc tggatattct
    29221 gaagctcggc ttccgtggct accgccatct ggcggagttt gcgccttctt cggtgaaggg
    29281 catattccgt gtgctgactt ctctggtttc ctgggttgta tcgtttattc cgcgccgccc
    29341 ggagcggagc gaaacggcac aaccatcgga tcaggctttg gctcaacaat gatgataacg
    29401 cgatgaaaag aaaactattc tggatttgtg cagtggctat ggggatgagt gcgttcccct
    29461 ctttcatgac gcaggcgacg ccagcaacgc aaccactgat caatgctgag ccagctgtag
    29521 ccgcccagac ggaacaaaat ccgcaggtgg ggcaagtgat gccgggcgtg cagggcgctg
    29581 atgcgccagt cgtggcgcag aacggtcctt cgcgtgatgt gaagctgacc tttgcgcaaa
    29641 ttgcaccgcc gccgggcagc atggtgctac gtggcattaa cccgaacggc agcattgagt
    29701 ttggtatgcg cagcgatgaa gtggtgacga aggcgatgct caacctcgaa tacaccccat
    29761 cgccatcgtt actgcctgtc cagtcgcagt taaaggttta tctcaatgat gaactgatgg
    29821 gcgtgctgcc agtgaccaaa gaacagttgg gtaaaaaaac gctggcgcaa atgcccatta
    29881 acccactgtt tattaccgac ttcaaccgtg tacggctgga gtttgtcggc cattatcagg
    29941 acgtgtgcga aaacccggcc agcaccacgc tttggctgga tgttgggcgg agcagtggac
    30001 tggatctgac ctatcagacc ctgaatgtga agaatgacct gtcacacttc ccggtgccat
    30061 tctttgaccc gcgcgataac cgcaccaaca ccttgccgat ggtctttgcg ggtgcgccgg
    30121 atgttgggct gcaacaagcc tctgccattg tcgcctcgtg gtttggttcg cgttctggct
    30181 ggcgtgggca gaacttcccg gtactctata accaactgcc ggatcgcaat gccattgtct
    30241 ttgcaaccaa cgacaaacgg ccggacttcc tgcgcgatca tccggcggta aaagccccgg
    30301 tgattgagat gattaaccat ccgcagaatc cttacgtcaa actgctggtg gtgtttggtc
    30361 gtgacgacaa agacctgttg caggcagcga aaggtatcgc tcagggtaac attctgttcc
    30421 gtggtgaaag cgtggtagtg aatgaagtga aaccgctgct accgcgtaag ccgtacgatg
    30481 cgccgaactg ggtacgtacc gatcgtccgg tcacatttgg cgaactgaaa acctatgaag
    30541 aacagttaca atccagcggt cttgagccag cagcgattaa cgtttcgcta aacctgccgc
    30601 cggatctcta cctgatgcgc agtaccggca ttgatatgga tattaattac cgctacacca
    30661 tgccgccggt gaaagacagt tcgcggatgg atatcagcct gaataaccag ttcctgcaat
    30721 ccttcaacct gagcagcaaa caggaggcga accgcctgct gctgcggatt ccggtattac
    30781 aaggtttgct ggatggcaaa acagatgtct ctattccggc gctgaaactg ggcgcgacca
    30841 accagctgcg cttcgacttt gagtatatga acccgatgcc gggcggttcg gtggataact
    30901 gtattacctt ccagccggtg cagaatcatg tggtgattgg tgacgactcc accatcgact
    30961 tctcgaagta ttaccacttc atcccgatgc cggatctacg cgcctttgct aacgcgggct
    31021 tcccattcag ccggatggcg gatctgtcgc aaaccatcac cgtgatgccg aaagcgccta
    31081 acgaagcaca gatggaaacg ttgctgaata ctgttggttt tatcggcgca cagacgggct
    31141 tcccggcgat taatctgacg gtgaccgatg atggcagcac cattcagggc aaagatgccg
    31201 acatcatgat catcggtggt atcccggaca aactgaaaga cgataagcag atcgacctat
    31261 tggtgcaggc gaccgaaagc tgggtgaaaa caccgatgcg ccagaccccg ttccccggca
    31321 ttgtgccgga cgagagcgat cgcgcggcag aaacccggtc aacgctgacc tcttccggtg
    31381 cgatggcggc ggtgattggc ttccagtcgc cgtataacga ccagcgcagc gtgattgcgc
    31441 tgttggcaga tagcccacgc ggttatgaaa tgcttaacga tgcggtgaac gatagcggca
    31501 aacgcgccac catgttcggt tcggtcgcgg tgatccgcga gtccggtatc aacagcctac
    31561 gtgttggcga cgtttattac gtaggttatc tgccgtggtt cgagcgcgtg tggtatgcgc
    31621 tggcaaacca tccgattctg ctggcggtgc tggcggctat cagtgtgata ttgctggcat
    31681 gggtactgtg gcgtctgctg cgaattatta gtcgtcgtcg tcttaacccg gataacgagt
    31741 aattgaagat gaatgtgttg cgtagtggaa tcgtgacgat gctgctgctg gctgccttta
    31801 gtgttcaggc agcctgtacc tggcctgcct gggagcagtt taaaaaggat tacatcagtc
    31861 aggaagggcg cgtcatcgac cccagcgacg cgcgcaaaat caccacctcc gaagggcaaa
    31921 gttacggcat gttctctgcc ctggcggcta acgaccgtgc agctttcgat aatattctcg
    31981 actggacgca gaacaatctc gctcagggtt ctttaaaaga acgtttgccc gcctggctgt
    32041 ggggcaagaa agagaacagt aagtgggaag tgctggacag caattcggcc tccgatggtg
    32101 atgtctggat ggcctggtcg ttgctggagg cggggcgttt gtggaaagag cagcgttata
    32161 ccgacatcgg cagcgcgttg ctaaaacgta tcgcgcggga ggaagtggtg acggtgcctg
    32221 ggctgggttc catgttgtta ccgggcaaag tgggttttgc tgaggataac agctggcgtt
    32281 ttaaccccag ctacctgccg ccgacgctgg cgcagtattt cacccgcttt ggcgcgccgt
    32341 ggaccacgct gcgcgaaacc aatcaacgtt tattgctgga aaccgccccg aaaggttttt
    32401 cgccagactg ggtgcgctat gagaaagaca aaggctggca gctaaaagcc gaaaaaacat
    32461 tgatcagcag ctacgacgct atccgcgttt acatgtgggt aggcatgatg cctgacagcg
    32521 atccgcaaaa agcgcggatg ctcaaccggt ttaaaccgat ggcgacattc actgagaaaa
    32581 acggttatcc gccggaaaaa gtggatgtgg ctacggggaa agcgcagggt aaaggaccag
    32641 tcggtttttc tgccgccatg ctgccctttt tacaaaaccg cgatgcgcag gccgttcagc
    32701 gccagcgcgt ggccgataac tttcccggca gcgatgccta ttacaactat gtgctgaccc
    32761 tgtttggaca aggctgggat caacaccgtt tccgcttctc gacaaaaggt gagttattac
    32821 ctgactgggg ccaggaatgc gcaaattcac actaaacata ttcacgcttt ccctcggtct
    32881 ggccgtcatg ccgatggtcg aggcagcacc aaccgctcag caacagttgc tggagcaagt
    32941 tcggttaggc gaagcgaccc atcgtgaaga tctggtgcaa cagtcgttat atcggctgga
    33001 acttattgat ccgaataacc cggacgtcgt tgccgcccgt ttccgttctt tgttacgtca
    33061 gggcgatatt gatggcgcgc aaaaacagct cgatcggctg tcgcagttag cgccgagttc
    33121 aaatgcgtat aaatcgtcgc ggactacgat gctactttcc acgccggatg gtcgtcaggc
    33181 actgcaacag gcacgattgc aggcgacgac cggtcatgca gaagaagctg tggcgagtta
    33241 caacaaactg ttcaacggtg cgccgccgga aggtgacatt gctgtcgagt actggagtac
    33301 ggtggcgaaa attccggctc gccgtggcga agcgattaat cagttaaaac gcatcaatgc
    33361 ggatgcaccg ggcaatacgg gcctgcaaaa caatctggcg ctattgctgt ttagtagcga
    33421 tcgccgtgac gaaggttttg ccgtcctgga acagatggca aaatcgaacg ccgggcgcga
    33481 aggggcctct aaaatctggt acgggcagat taaagacatg cccgtcagtg atgccagtgt
    33541 gtcggcgctg aaaaaatatc tctcgatctt tagtgatggc gatagcgtgg cggctgcgca
    33601 atcgcaactg gcagaacagc aaaaacagct ggccgatcct gctttccgcg ctcgtgcgca
    33661 aggtttagcg gcggtggact ctggtatggc gggtaaagcc attcccgaac tacaacaggc
    33721 ggtgcgggcg aacccgaaag acagtgaagc tctgggggcg ctgggccagg cgtattctca
    33781 gaaaggcgat cgcgccaatg cagtggcgaa tctggaaaaa gccctcgcac tggacccgca
    33841 cagcagcaac aacgacaaat ggaacagtct gctgaaagta aaccgctact ggctggcgat
    33901 ccagcagggc gatgctgcgc tgaaagccaa taatcctgac cgggcagaac gcctgttcca
    33961 gcaggcgcgt aatgtcgata acaccgacag ttatgcagtg ctggggctgg gcgatgtggc
    34021 gatggcgcga aaagattatc ccgccgccga acgttattat cagcagacct tgcgtatgga
    34081 cagcggcaac actaacgccg tgcgcgggct ggcaaatatt taccgccagc aatcgccaga
    34141 aaaagctgaa gcgtttatcg cctcgctctc tgccagtcag cggcgtagca ttgatgatat
    34201 cgaacgcagc ctgcaaaacg accgtctggc acagcaggca gaggcactgg aaaaccaggg
    34261 caaatgggcg caggcggcag cacttcagcg gcaacgactg gcgctggacc ccggcagcgt
    34321 atggattact taccgacttt cgcaggatct ctggcaggcc ggacaacgca gccaggccga
    34381 tacgttaatg cgcaatctgg cgcagcagaa gtcgaacgac ccggagcagg tttacgctta
    34441 cgggctgtac ctctctggtc atgaccagga cagagcggcg ctggcgcata tcaacagcct
    34501 gccgcgtgcg cagtggaaca gcaatattca ggagctggtt aatcgactgc aaagcgatca
    34561 ggtgctggaa accgctaacc gcctgcgaga aagcggcaaa gaggcagaag cggaagcgat
    34621 gctgcgccag caaccacctt ccacgcgtat tgacctcacg ctggctgact gggcgcaaca
    34681 acgacgtgat tacaccgccg cccgcgctgc atatcagaat gtcctgacgc gggagccagc
    34741 taacgccgac gccattcttg gtctgacgga agtggatatt gctgccggtg acaaagcggc
    34801 ggcacgtagc cagctggcga aactgcccgc taccgataac gcctcgctga acacacagcg
    34861 gcgcgtggcg ctggcacagg cgcagcttgg cgataccgca gcagcgcagc ggacgtttaa
    34921 taagttgatc ccgcaggcaa aatctcagcc accgtcgatg gaaagcgcga tggtgctgcg
    34981 tgatggtgcg aagtttgaag cgcaggcggg cgatccaacg caggcgctgg aaacctacaa
    35041 agacgccatg gtcgcatccg gtgtgactac gacgcgtccg caggataacg acacctttac
    35101 ccgactgacc cgtaacgacg agaaagatga ctggctgaaa cgtggcgtgc gcagcgatgc
    35161 ggcggacctc tatcgccagc aggatcttaa cgtcaccctt gagcacgatt actggggttc
    35221 gagcggcacc ggtggttact ccgatctgaa agcgcacact accatgttgc aggtggatgc
    35281 gccgtattct gacgggcgga tgttctttcg cagtgatttc gtcaatatga acgtcggcag
    35341 tttctccact aatgccgatg gcaaatggga tgacaactgg ggcacctgta cattacagga
    35401 ctgtagcggc aaccgcagcc agtcggattc cggtgccagc gtggcggtcg gctggcgaaa
    35461 tgacgtctgg agctgggata tcggtaccac gccgatgggc ttcaacgtgg tggatgtggt
    35521 cggcggcatc agttacagcg atgatatcgg gccgctgggt tacaccgtta acgcccaccg
    35581 tcggcccatc tccagttctt tgctggcctt tggtgggcaa aaagactccc cgagcaatac
    35641 cgggaaaaaa tggggtggcg tacgtgccga cggtgtgggg ctaagtctga gctacgataa
    35701 aggtgaagca aacggcgtct gggcatcgct tagtggcgac cagttaaccg gtaaaaatgt
    35761 cgaagataac tggcgcgtgc gctggatgac gggctattac tataaggtca ttaaccagaa
    35821 caatcgccgc gtcacaatcg gcctgaacaa catgatctgg cattacgaca aagatctgag
    35881 tggctactca ctcggtcagg gcggttacta cagtccgcag gaatacctgt cgtttgccat
    35941 accggtgatg tggcgggagc gcacggaaaa ctggtcgtgg gagctgggtg cgtctggctc
    36001 gtggtcgcat tcacgcacca aaaccatgcc gcgttatccg ctgatgaatc tgatcccgac
    36061 cgactggcag gaagaagctg cgcggcaatc caacgatggc ggcagcagtc agggcttcgg
    36121 ctacacggcg cgggcattac ttgaacgacg tgttacttcc aactggtttg ttggcacggc
    36181 aattgatatc cagcaggcga aagattacgc acccagccat ttcctgctct acgtacgtta
    36241 ttccgccgcc ggatggcagg gtgacatgga tttaccgccg cagccgctga taccttacgc
    36301 cgactggtaa gttttcagat agcgcctctc ttaatgccgc tgcgatcggg tatactcggg
    36361 cggcaatctg ggatttccgg ggggagacaa tttgcgcgta agtcgctcgt taacaatcaa
    36421 gcagatggca atggtggcag ccgttgtcct ggtgttcgtt tttatttttt gcaccgtttt
    36481 gctgttccat ctggtccagc agaatcgcta taacacggct acgcaactgg aaagcattgc
    36541 tcgctctgtc cgcgaaccct tatcttcagc tattttgaaa ggcgatattc ccgaagcgga
    36601 agctattctt gccagcatta aaccggcagg cgtggtcagc cgtgccgatg tagtgctgcc
    36661 taaccagttc caggcgctgc gtaaaagttt tattccagag cgcccggtgc cggtaatggt
    36721 tactcgcctg tttgagctac cggttcaaat ctcgctgggc gtttactcgc tcgaacgtcc
    36781 ggcaaacccg cagccaattg cctatctggt actacaggcg gattccttcc gtatgtataa
    36841 gttcgtgatg agcaccctct caacgttagt gaccatttac ttacttttgt cgcttatcct
    36901 gaccgtcgcc atcagctggt gcattaaccg cctgattttg catccgttac gcaatattgc
    36961 tcgcgaactt aacgccatcc cagccaagga gcttgttggt caccaactgg cattaccgcg
    37021 tctgcatcag gacgatgaaa tcggtatgtt ggtgcgcagt tacaacctca accagcaatt
    37081 gctgcagcgc cattatgaag aacagaacga aaatgcgatg cgcttcccgg tgtcggattt
    37141 gccgaacaaa gccttgctga tggagatgct ggagcaggtt gtcgcgcgta aacaaaccac
    37201 cgcgctgatg atcatcacct gtgaaaccct gcgtgatact gcgggcgtgc tgaaagaggc
    37261 gcaacgagaa attctgctgc tgacgctggt ggaaaaactc aaatcggtac tgtcgccacg
    37321 tatgatcctc gcgcagatta gcggttatga ctttgctgtc attgccaacg gtgtacagga
    37381 accgtggcac gcaatcacct taggtcagca agtgctcact atcatgagcg agcgcctgcc
    37441 gattgaacgt attcaactcc gtccgcactg tagcattggc gtggcgatgt tctacggcga
    37501 tctcaccgcc gaacagcttt acagtcgcgc tatttctgcg gcatttaccg ctcgccataa
    37561 aggcaagaat cagattcagt tctttgatcc gcagcagatg gaagccgccc agaagcggtt
    37621 gacggaagag agcgatatcc ttaatgcact ggaaaatcat cagtttgcta tttggttaca
    37681 gccacaggtc gagatgacca gcggtaaact ggtcagtgcg gaagtgttac tgcgtatcca
    37741 gcaaccggat ggcagttggg acctgccgga tggcttaatc gatcgcattg agtgctgtgg
    37801 gctgatggtt accgtcggtc actgggtgct ggaagagtcc tgtcgattgc ttgcagcctg
    37861 gcaagagcgc ggcattatgc tgcccttgtc ggtaaacctc tctgcgctgc aactgatgca
    37921 cccgaatatg gtggcggata tgctggaact gttaacccgc tatcgcattc agccgggaac
    37981 actgattctg gaagtgacag aaagccgacg tattgacgac cctcatgctg cggtggcaat
    38041 cctccgtccg ctgcgcaatg ccggagttcg ggtggcgctg gatgatttcg gcatgggcta
    38101 cgcagggctg cgtcagctgc agcatatgaa atcgttgcca atcgacgtac tgaaaatcga
    38161 caaaatgttt gttgaaggct tgccgggaga tagcagcatg attgctgcaa ttatcatgct
    38221 ggcgcagagc ctgaacttac aaatgattgc cgaaggcgtg gagactgaag cacaacgcga
    38281 ctggctggca aaagcgggcg ttggtattgc ccagggcttc ctttttgctc gcccactccc
    38341 tattgaaatc ttcgaagaga gttacctgga agaaaagtag ctaccccaaa ctgattacaa
    38401 aactttaaaa agtgctggtt tgtgcgagcc agctcaaact ttttaacctt tttgtttcaa
    38461 ttatgatcca ggtacatttc tgtgatgttg tctgggtgtt attttaaggc cgcaggtacc
    38521 ccataacctt acaagacctg tggttttact aaaggacacc ctatgaaaac ctctctgttt
    38581 aaaagccttt actttcaggt cctgacagcg atagccattg gtattctcct tggccatttc
    38641 tatcctgaaa taggcgagca aatgaaaccg cttggcgacg gcttcgttaa gctcattaag
    38701 atgatcatcg ctcctgtcat cttttgtacc gtcgtaacgg gcattgcggg catggaaagc
    38761 atgaaggcgg tcggtcgtac cggcgcagtc gcactgcttt actttgaaat tgtcagtacc
    38821 atcgcgctga ttattggtct tatcatcgtt aacgtcgtgc agcctggtgc cggaatgaac
    38881 gtcgatccgg caacgcttga tgcgaaagcg gtagcggttt acgccgatca ggcgaaagac
    38941 cagggcattg tcgccttcat tatggatgtc atcccggcga gcgtcattgg cgcatttgcc
    39001 agcggtaaca ttctgcaggt gctgctgttt gccgtactgt ttggttttgc gctccaccgt
    39061 ctgggcagca aaggccaact gatttttaac gtcatcgaaa gtttctcgca ggtcatcttc
    39121 ggcatcatca atatgatcat gcgtctggca cctattggtg cgttcggggc aatggcgttt
    39181 accatcggta aatacggcgt cggcacactg gtgcaactgg ggcagctgat tatctgtttc
    39241 tacattacct gtatcctgtt tgtggtgctg gtattgggtt caatcgctaa agcgactggt
    39301 ttcagtatct tcaaatttat ccgctacatc cgtgaagaac tgctgattgt actggggact
    39361 tcatcttccg agtcggcgct gccgcgtatg ctcgacaaga tggagaaact cggctgccgt
    39421 aaatcggtgg tggggctggt catcccgaca ggctactcgt ttaaccttga tggcacatcg
    39481 atatacctga caatggcggc ggtgtttatc gcccaggcca ctaacagtca gatggatatc
    39541 gtccaccaaa tcacgctgtt aatcgtgttg ctgctttctt ctaaaggggc ggcaggggta
    39601 acgggtagtg gctttatcgt gctggcggcg acgctctctg cggtgggcca tttgccggta
    39661 gcgggtctgg cgctgatcct cggtatcgac cgctttatgt cagaagctcg tgcgctgact
    39721 aacctggtcg gtaacggcgt agcgaccatt gtcgttgcta agtgggtgaa agaactggac
    39781 cacaaaaaac tggacgatgt gctgaataat cgtgcgccgg atggcaaaac gcacgaatta
    39841 tcctcttaat ctcatcactt atgcccgcac tcccttcccc gagtgcgggt gtttgcgcat
    39901 aattgacccc tgtgcctgaa cttaccacct gggtgagttc aggtttattt cacttcttcc
    39961 gtgacatttt catgttcttg cggtctaaca cgaagtgttt ttaacgtcat ttagactgac
    40021 cgacaacggg cagttttttt attaccagga tagttgatca ggggttcaca tgcagggcac
    40081 aaaaattcga cttttagcgg gcggtttgct gatgatggcc actgctggct atgtgcaggc
    40141 agatgcgctc cagcctgatc cagcatggca acaggggacg ctttccaacg gtttacagtg
    40201 gcaagtgctg accacccccc agcgtcccag cgatcgtgtt gaaattcgcc tgctggttaa
    40261 taccggttcg ctcgccgaaa gtacacaaca gagcggttac agtcacgcca tccctcgtat
    40321 tgcgctaacg caaagcggtg gccttgacgc agcacaggcg cgttcattgt ggcagcaggg
    40381 gatcgaccct aaacgcccga tgccgccggt aattgtctct tatgacacca cgctgtttaa
    40441 tctgagtttg cccaataacc gtaacgattt gctgaaagaa gcgctctctt atctggcaaa
    40501 tgccactggc aaattgacca tcacaccaga aaccatcaac cacgcgctgc aaagtcagga
    40561 catggtggca acctggcctg ccgatactaa agagggctgg tggcgctatc gtctgaaagg
    40621 gtcaaccttg ttaggccacg atcctgccga tccgctgaaa caacccgttg aagcggaaaa
    40681 aattaaagat ttctatcaga aatggtacac cccggatgca atgacgctac tggtggtggg
    40741 aaacgtggat gcgcgctcgg ttgtcgacca aataaacaaa acgtttggcg aactgaaagg
    40801 caaacgtgaa acgccagctc cggtgccgac gctttctccg ctgcgtgcgg aagcggtgag
    40861 tattatgact gacgcggtgc gtcaggaccg gttatctatc atgtgggata cgccgtggca
    40921 gccgattcgt gaatcagccg cactgctgcg ctactggcgt gcggacctgg cccgcgaggc
    40981 gctgttctgg catgttcagc aagcgttaag tgccagtaac agcaaagaca tcggtcttgg
    41041 atttgactgc cgtgtgctgt atctgcgtgc gcagtgtgcc atcaacatcg aatcaccaaa
    41101 cgacaagctg aacagcaacc ttaatctggt ggcgcgtgaa ctggcgaagg ttcgcgataa
    41161 aggtctgccg gaagaagagt tcaatgcgtt agtggcgcaa aagaaactgg agctgcagaa
    41221 actgtttgcc gcctatgcac gagctgatac cgatattctg atgggtcagc ggatgcgttc
    41281 gttgcaaaat caggttgtcg atatcgcgcc ggagcaatat cagaaactgc ggcaggattt
    41341 ccttaatagc ctgacggtag agatgttaaa tcaggatctg cgtcaacagt tgtcgaatga
    41401 tatggcgtta atactgctgc agccgaaagg cgagccggaa tttaacatga aagcgttgca
    41461 ggcggtctgg gatcaaatca tggccccatc taccgccgct gcgaccacct ctgtcgccac
    41521 ggatgacgta catcctgaag tgacggatat tccacctgca cagtaatgcc tgatggtgat
    41581 gagttagcac aaccatcagg tatttatgga tgagctggat agaggggtaa cactttatcc
    41641 agccttttgc atatgctgcg tttacgctgg catcgcctca cgcgggataa tcgcgccgcg
    41701 atactgaata acggtacttg cggtcaggtg cccacgtttc gccgcgtctt ccgcgctgcc
    41761 gcctgtcaga cgtaccgcca gataaccggc actgaaagag tcgccagctg cggtggtatc
    41821 gatcactttt tctttcggca gtttcaccgc cggaacatcc actaaccctt cgccagcaat
    41881 ggacaccagg caagaatccg ccccgcgttt caccaccact tctttcacgc ccgcgttatg
    41941 ggtgcgcgca atgacgtctt ccaccggctg ttgaccccac agcgcgtctt cgtcgtccag
    42001 cgtcaggaag gcgatatccg tgcattccag catttgttgg tacacctgct gtgtctcttc
    42061 tttgctggcc cacaggcgcg gacgatagtt attgtcgaaa atcacttttc cgccgttggc
    42121 gcggcattcg cgcagcaggg aaagcagctt ttcgcggctg gtcgggctta agatcgccag
    42181 gctaatcccg ctcaggtaga gataatcgaa attcgccagc tcttcgcaaa tcgccgcaga
    42241 ctgctcactc tccagccaga atttggcggc ggcttcgttc cgccagtagt agaacgtacg
    42301 ctcgccggtg ctgtcggttt caatgtagta aaggcccggc agacggtttt ccatccgttg
    42361 ggtcagggaa gtatcaacgt tctcgccgtg ccaggcgtcc agcatctgct ggctaaaact
    42421 gtccgttccc agcgccgtta cgtaatgaac ggttaatgcc gcaggatcga cctgacgggc
    42481 gatatagacg gaagtgttca gggtatcgcc gccgaaaccg cgcttaacgt ccgcgccttt
    42541 ctcggaaagc tcaatcatgc attcgccaat cacggcaatc tttttggaca tagtcgtgaa
    42601 cctgatctgt aaaaaattag cgttagtttg cgctgtggtg gtttgctggt caaccatatt
    42661 aaaacagtgt tccattattt ttttgagcca gaacgtattc ctgaaagatt ccgttgtgga
    42721 gtgaggaaat ttaccccggc caggcggtaa agttctgccc ttacgcgccg ataatctttg
    42781 tcgagtccgg gcagcatcac ttttaaacac aggacatctt tgatgataag gcaggttatc
    42841 cagcgaataa gcaaccctga agcaagcatc gagagcttgc aggaacggcg tttttggttg
    42901 cagtgtgagc gtgcttacac ctggcagccg atctatcaaa catgcgggcg gttaatggcc
    42961 gtggagctat taacggtggt cacgcatccc ttgaaccctt cgcaacgcct gccgccggat
    43021 cgctatttta ctgaaatcac cgtcagccat cggatggagg ttgtgaaaga gcagattgat
    43081 ttgctggcgc aaaaagccga cttctttata gagcacggcc tgctggcatc ggtcaatatt
    43141 gatggcccta cgctcatcgc cctgcgtcag caaccaaaaa tcctgcgcca gattgagcgt
    43201 cttccctggc tgcgtttcga actggtggag catatccgtc tgccgaaaga ttcaaccttt
    43261 gcctcgatgt gtgaatttgg cccgctgtgg ctggatgatt ttggtaccgg gatggcaaat
    43321 ttctctgcgc taagtgaagt gcgttatgac tacatcaaaa tcgcgcgaga actgtttgtg
    43381 atgctgcgtc agtcgccgga aggacgcaca ctcttttctc agcttttaca tctaatgaat
    43441 cgctattgtc gcggggtgat tgtcgagggc gtagaaacgc cggaagagtg gcgtgatgtt
    43501 cagaactcgc ccgcattcgc cgcacaaggc tggtttcttt cacgcccggc accgatagaa
    43561 acgctgaata cggcggttct ggcgctataa gctgcctcat tttccgcctg gctggactat
    43621 ctttaggact ggcacaggaa gaatatgagg aagcgaacga tgagcaaggc aggcaaaata
    43681 accgctgcga tttcaggggc tttcttgttg ttgattgtcg tggcgatcat tttgattgca
    43741 acttttgact ggaatcgact caaaccgact atcaaccaga aagtctctgc ggagttgaat
    43801 cgtccgttcg ctatccgtgg cgatctgggc gtggtgtggg agcggcaaaa acaagaaact
    43861 ggctggcgca gctgggtgcc gtggccccat gtacacgcgg aagacatcat tcttggcaat
    43921 ccaccggata ttcccgaagt cacgatggtg catttgccac gcgtagaggc aacgctggcc
    43981 ccgctggcgc tgctgaccaa aacggtctgg ctgccgtgga tcaagctcga aaagcccgac
    44041 gcgcgcctga ttcgcctctc tgaaaagaac aataactgga cgtttaatct tgccaacgat
    44101 gataacaaag acgcgaatgc aaagccgtcg gcatggtcgt ttcggctgga taatattctt
    44161 ttcgatcaag ggcggatcgc cattgatgac aaagtaagca aagcggatct ggagattttt
    44221 gttgatccct taggcaagcc gctgccgttc agcgaagtta ctggatcgaa aggtaaagcg
    44281 gataaagaaa aggtgggcga ttacgttttt ggcctgaagg cgcagggacg atataacggt
    44341 gaaccgctca cgggtacggg aaaaataggc ggtatgctgg cgctgcgtgg cgaagggacg
    44401 ccgtttccgg tacaggctga tttccgctct ggtaacaccc gtgttgcttt tgatggcgtc
    44461 gtgaatgacc caatgaagat gggcggtgtc gatttacggc ttaaattttc tggcgattca
    44521 ctgggtgatc tctatgaact gacgggcgtt ctgctgcccg ataccccgcc gtttgaaacg
    44581 gatggtcggc tggtagcgaa aatcgacact gaaaaatcgt cggtctttga ttatcgcggt
    44641 tttaatgggc gaattggtga tagcgatatc cacggttctc tggtctacac caccggaaag
    44701 ccacgaccaa aactggaagg tgatgtcgag tcgcggcaat tgcggctggc ggacctggga
    44761 ccgttgattg gcgttgattc cgggaaaggg gcagaaaagt cgaaacggtc tgaacagaag
    44821 aagggcgaaa aaagcgttca gcctgcgggc aaagtgctgc cttatgaccg cttcgaaacc
    44881 gataaatggg acgttatgga tgccgatgtt cgcttcaaag ggcggcgcat tgagcatggc
    44941 agtagcctgc cgattagcga tctttctact catatcatcc tcaaaaatgc tgacctgcgc
    45001 ctgcaaccgc tgaaatttgg catggcgggc ggcagcattg cggcgaatat tcatctggaa
    45061 ggcgataaaa agccgatgca ggggcgggca gatattcagg ctcgtcgact gaaactgaaa
    45121 gaactgatgc ccgatgtgga actgatgcag aagacgctgg gggaaatgaa cggtgacgcg
    45181 gaactacgcg gtagcggtaa ctcggtggcg gcacttttag gcaacagtaa cggcaacctg
    45241 aaactgttga tgaatgacgg gctggtgagc cgcaacctga tggagattgt tgggctgaat
    45301 gtcggcaact acattgtcgg tgcgatattt ggtgatgatg aggtgcgggt gaactgcgcg
    45361 gcggcgaatc tgaatattgc caacggcgtg gcgcgcccgc agatttttgc tttcgatact
    45421 gagaacgcgt tgattaatgt taccggcacg gcaagttttg cttcggaaca gctggatttg
    45481 actattgatc cggagagtaa aggaattcgg attatcacac tgcgttcgcc gctgtatgtg
    45541 cgggggacgt ttaaaaatcc gcaggctggg gtgaaagccg gaccgctgat tgcccgtggt
    45601 gctgttgctg cggcactggc aacgctggta acaccggcgg cggcgttact ggcactgatc
    45661 tcaccttccg aaggggaggc taatcagtgt cggacgattt tgtcgcagat gaagaagtga
    45721 tgataattgc cggatgtctg acatccggca attaaacaga tttagattgt tggcaaagtg
    45781 tgctttgttc atgccggatg cggcgtgaac gccttatccg gcctacaaat ccttgcgaat
    45841 tcaatatatt gtatggaaat tcaggcctga taagcgtagc gcatcaggct tttcactctt
    45901 attacaacga ctgatgtcgc gtctcatggg tcagcagcag ggcgattaac gtcaagccag
    45961 ccatcgccgc cagatataac cccaccgcac ctagcccgta gttagtctgc aaccaggctg
    46021 cgatatatgg cgcaacggaa gccccgagaa tcgacgctac gttgtaagag aacgatgctc
    46081 cggtgtaacg cacttctgtc ggaaacagct ctggtaacag cgcacccatt ggcccgaagg
    46141 tcagacccat cagacttaac cccagcagca ggaaggcaaa aaccagaatc gggttgccag
    46201 aaccgagcag tgggttaaag gcgaacagcg cgaacaggat gatcagcgtg gtgatgatta
    46261 ccatgctttt acggcgacca aaggcatcag ccagtaatcc agcgactggc accatcacgc
    46321 caaaaccaat aactgccatc atcaacatcc acaacacttc gttacgcggc aggccaagcc
    46381 caactggcgc ggcggcggta ctaaaggtca tagagtagac cgtcatgatg taaaacagcg
    46441 tataggttgc cagcataatg aacgtaccca gtacggttac gcgaacatgt ttggtcagca
    46501 gcgtacccag cgggatcttc acctgttttt tcgctttagc gactttctca aacaccggcg
    46561 actcatgcag cgacacgcga acatacaggc cgataatgac cagcaccgcc gagaagataa
    46621 atggcacacg ccagccccag ctcataaact gctcgtcggt cagtagccag gaaagcagca
    46681 agaaagtgcc attggcaaag aagaagccaa tcggtgcgcc cagctgcgga aaggagccat
    46741 acagtgcacg tttgcgcggt ggggcgtttt cagtcgccag cagcgccgcg ccgccccatt
    46801 caccgcctaa gcccagaccc tgaccaaatc gagccagcgc cagcagcagc ggggcgaaaa
    46861 taccaatcgt ggcatagccc ggcagcagac caatcaccac ggtcgaaatc cccatcgtta
    46921 gcaacgaggc gaccagcgtc gctttacgcc caacgcgatc gccaaaatga ccaaaaacgg
    46981 cagagccaat ggggcgcgcg acgaaggcga tggcgaaggt ggcgagcgac tgtagcgttg
    47041 ctgccgtagg atcgccctgc gggaagaaga tatgcggaaa cacaataacg gccgcagtgg
    47101 cgtaaatgta aaagtcgaag aactcaatgg ctgtgccaat gagagaggcg acaaggactt
    47161 tattacgcga gttgatcggc gtgtattctt gctcgtggtc gagtgttgtg gctgttgctt
    47221 gcataatctt ttcttatttt ttggctaacg aatagccata ttacgcacag caaaagtgat
    47281 atttcaatgt gtaacaaatc gcggaaatgg tcaaaaatca ggcaaaaagg ggataatgtt
    47341 taggccagtg atttttcttc tatgaaatgc ttcacataat tttataaata gtggataaaa
    47401 ctggtttcag gttaaataaa agttaccaac tggatttata tgctggggtt atgagttgga
    47461 atgaaattgt ttgctcccaa atagatggct gaagaggctc tggggacgag tttcaagagg
    47521 ttatgtgcgc attatagccg gatgcgatgc tggcgcatct tatccggcct acggggagcc
    47581 aggccgaata aaatcgtatg ccggataagg cgtttacgcc gcatccggcc tattttaagg
    47641 ctgcgttttc cccggcattc gcgggtcgtc tttatattcg gcggtggcaa tccacgccgc
    47701 gcaaaacagc gtcaaacggg cgaagaagta gaaaaatgcc atcagcccca gcacggaacc
    47761 aaatgctgcg ccagaggggg atttcatcaa cgatggcagg gtgtaggtca tcacgatttt
    47821 aatcacttca aaaccaatag cagccagaaa tgttccgcga atcagggctt ttttgcgcgg
    47881 acggtggcgc ggcaaccgcc agaagatcca gaagaaaagc agatagttgg cgaagatgga
    47941 aatcgccagg ccaatcaatc gccacgtcgg tttcagccac tcaatgctgt tcaggtgcag
    48001 ggcgctaata atcatttgct gcgccgaacc ggcaaccgag gtgatcgaaa gcgtcacaat
    48061 cagcgcaatc aacaaaccaa tcagcgaaat aaaatctcgc agatatttta cccagaactt
    48121 ctcctgatct tgcggcgagc gttcccagac atcgcgcgac tgggcacgaa tcgcttcacg
    48181 caggttaccc atccagttga tgccggaata aagtgccacc gccaggccga caagccctac
    48241 agtcgtacgc tgctgaacgg cggtgttgat ggtgtttttc aacgtggcgg ctagcgtcgg
    48301 atcgctgatg ttttgcagaa ttttgtcgaa gatatcctgt agcaacatcg gatgggaggc
    48361 cagcacaaag ccccctgcgg caaacgacac catcaaaatt ggtatcatcg acaaaaatga
    48421 gaaataggtg atagccgcac caaactggtt acccagccga tcgttaaagc gttctgtcgc
    48481 gcgaatcagg tgcgcaataa ccggttggcg ttggactttt tcggcagtgg tggtgacggt
    48541 ttccagcgcc tggctaactt tgctgccttt ctcgctatta tccaacggct taatcggctc
    48601 gtgctccaga tcctggatgg gacgtttgat ctcgttttcc tgcgtcatcc gctcttttgt
    48661 ccttctgtcg tggtcattct taaaaagtat agtcggtcag tccaggtact ctttcattac
    48721 gccagccagc cactgcataa acaggtttac acgccgggaa agctcccgac gctgcggata
    48781 aaccagcgaa agggagagcg gctcggcacg gtagccaggt aatacttcaa taagccgccc
    48841 ggcacgcagg gcttcgcgca cggcaatgcg cgggatctga ataatcccca gaccggcaag
    48901 accggcggtg agatagtttt cgctactgtt taccgtcaac atgccgccag acttaaacca
    48961 ctggacgcca ttaacgctgg caacctcaaa acctaacgga tgtacaccca ggtgcggtgt
    49021 ataacgcact attgcgtgtg aagtcagatc atcggggctt tgcggataac caaagcgcgt
    49081 cagatagtgc ggactggcac agttgaccat ggtcagtttg ccgaggggac gggcgataac
    49141 gccatcttcc ggtaacgcgc cagtgcgtat cacgcaatca aaaccatcat gaagaatatc
    49201 taccggacgg tcatggctac tcagttccag ctcaattccc ggatgcagat agagaaattc
    49261 cgacaggcgc ggcagtaaca ggcttttcgc gattcctggc gggatgtcga tgcgtaattt
    49321 accgctgata ctggtggcat cctgttgaaa cagaccgtcc agttcgctga gattactcaa
    49381 cacatctttt gctcgttgat aataggtcat gccttctggc gtgagtttga cccgtcgcgt
    49441 ggtgcgctgg agaagctggg tgccaagttg atgttccagt gcctgtatct ggcgcgaaac
    49501 acttcccttt ggcaaagcaa agaaatccgc tgcgcgggaa aaactttcca gctccgcgac
    49561 tttgatgaac aactgcattg cgtgaatttt atccatttct ttgaccgatt gttgttcaca
    49621 gcgaaacagt aacgcgcata tcgcattgtt tattgttttt tctaacatct aatgccgggt
    49681 ttcacaatgt tgtcatgccg aatgtggcga tttctcagca ggaaaagggc ggaatagctt
    49741 tctgagaaag gtgaatcccc ttaaacagag cgtatttttc agcgattccc tttaaagtga
    49801 acagaggacg tgttggctat ttgtgcttat ttttgtctcc ttgccgtttg ttattttggc
    49861 ttgtggtcgc ggaatttcat ttttaattgc atgcgtacta accaccaata taaggaaatc
    49921 ctcaaaattg ttttaaatag tgccctcgac atgtaatttc aggcgtttag ctgtaactat
    49981 ttatatcggt aactattttc tacacgtcat ctctgtagaa tggccaccgc caaatggcga
    50041 attcttattt tttctcgcgg gtaataccct tccactactt aagtcttttt aacgtattca
    50101 ggtggagatt cagttatgca aatagtcatg tttgacaggc agtcaatatt tattcatgga
    50161 atgaaaatca gtttacagca gcgtattcca ggagtgagta ttcagggggc cagtcaggca
    50221 gacgagttat ggcaaaagct ggaaagttac cctgaagcct tagttatgct cgatggcgat
    50281 caggatggtg agttttgcta ctggttgctg caaaaaaccg tggtgcaatt tcctgaggtt
    50341 aaggtgttaa ttacggcgac ggattgcaat aaacggtggt tacaggaagt tatccatttt
    50401 aatgtgctgg ccattgtgcc tcgtgattca accgtcgaga catttgcgtt ggcggtaaat
    50461 agtgcggcga tggggatgat gtttctgcct ggagactggc ggacgacgcc ggaaaaggac
    50521 attaaagatc tcaaatcgtt aagcgcccgc cagcgggaga ttttaaccat gttagcggcg
    50581 ggcgaatcaa ataaggagat cggcagagcg ctgaatatca gtaccggaac ggtaaaagcg
    50641 catctggaat ccctgtatcg ccgtctggaa gtgaaaaatc gcacccaggc ggcaatgatg
    50701 ttaaatatct cctcctgaag aggataattt tacagccagc aggaagttag cggctggctg
    50761 taaaaatatt atggttcgcc gtacaaacca attaaacggc gtaccacacc gttagtccag
    50821 ccaaacccat cctgcaacgg atactcgcca ccgccgcctt cgcggggaac accatcggca
    50881 atatggtatt tttcgatcag tttgtgctgt tccagataga actgattcac cgtcttcagc
    50941 cagcttcgcg cgatttcatc acccagaagg tcatcgccgt acattttaaa tccctgaatc
    51001 gccatccatt gtaacggtgc ccagccgttg ggtttatccc actgttcacc ggtttcgtac
    51061 tcgcttgcca gaatcccgcc aggtgtcagt aaccgactgc gcacggcgtt tgccagacga
    51121 tcggcctgtt catggttcgc cataccgaca tagagtggca caatggcggc agcggaaaac
    51181 agcgccagtt gttcgcgtcg ccagtcgtaa tcgcggtaga tgccgttttc atcatcccag
    51241 aggtaacggt ttaccgcatc gcgacgggca ctggctttct ggcggaacag tgcttctgtc
    51301 tctttctcgc ctttcagcgc cgagatgttg gcgatggcgc tctccagttt aaacaggaag
    51361 gcattcagat cgatggggat gaactgggtg gtacgaatgc tcgccagacg accagtatca
    51421 cgcagccaac gggaagagta atcccaaccg gaggccgccc ccgcgcgtaa atcgcggtac
    51481 acctcgttgg gcgggcgacc agaatgtttc gcggtttcaa cgtcctcaag ccaggattcg
    51541 tcacgcggcg tgtcgcgatc gtcccagtaa cggttgagca gcgatccgtc cggcatccgc
    51601 acaacatggc gataggcctg attagggatt aacgattctg caccgtccat ccagaaggca
    51661 tattccattt taaggtggtc gagatagcgg cgcgcaccgc gtacaccatc ttcttcaaac
    51721 aactccacca tcagcgcaaa aaccggtggt tgcgagcggc tcaaataata ggtgcggttg
    51781 ccgttgggga tgtgaccgta gttttcgatc atccaggcga agttatcggc catgcatttc
    51841 agcaaatctt cccgaccact ttccgccagc cccagcatgg tgaaatagga atcccaatag
    51901 taggtttcgc taaaacggcc gcccgggaca atatatgact gcggcagcgc cagcagagaa
    51961 gaccacggaa tgtgatcctg tggttcgcgg gttagcaccg gccacagctg gtcgatatgc
    52021 tctttcaggg aattttgcgg gtccgataca tactcgctgg agtagacctc cggcagccag
    52081 aagtggtttt caacaaactt gcgcaagtca aaatcacgat gacggcgcac tttacggtag
    52141 cggattaaga tatccagcgg gtccatttta ggtgcgcagt cgggaaaggt tttactgtcg
    52201 gggaaaattt tcgccgactg aacatgctcg aacagttcga gatagcgatc ggcaggcgtc
    52261 agcgcatcag aggcaggcag cccttcaatc atctcgggtt ccggttctgc ctcgatcatc
    52321 tcatccagtt ttaattcata cgggtccagc tcatagcaga gatcgacttc gatcatcagt
    52381 tcgtctggat tagggttttg aattttctga ttgagcataa ggatccaacc tccgaaattc
    52441 gtcgctaatt atcggctttt ctttaagggt agtcattcgc tccgcctggt gggcgacaaa
    52501 gcgtgcggtg gatcacgttt attaacctgt caaaaaatat aacgcactaa tatcaatgga
    52561 atttataaaa ataccgattt ggtgttgttt ttcattttca gaacattcaa tcctgctctc
    52621 gccgcaatca tgatatgcca ttcctgatct gggtaatagg cacaggctat cttattgata
    52681 gtttatattc atgtaattga ttgattccta tcaaaaagcg tatctccctg ttttttatga
    52741 tggctttgtc tcgcagagac gtttgcagca ttctggaaaa ttttctgggt cacaataact
    52801 caccaccgtg agggaagaat aatgaaaatg gtctcacgta ttaccgcgat cggcctggct
    52861 ggcgtcgcga tttgctattt agggttatct ggttatgtgt ggtaccacga taataaacgc
    52921 agtaaacagg ccgatgttca ggcatctgct gtcagtgaaa ataataaggt tttaggcttt
    52981 ctccgcgaaa aaggatgcga ctattgccac acgccttcgg cagaattacc cgcctattat
    53041 tatattcctg gcgcgaaaca gttgatggat tacgacatta agcttggata taaatctttt
    53101 aaccttgagg ccgtgcgtgc ggcactgctg gctgataaac ccgtttcgca aagcgatttg
    53161 aataagattg aatgggtgat gcagtatgaa actatgccac caacgcgtta taccgcgcta
    53221 cactgggcgg gtaaggtgag tgatgaagag cgggcggaaa tactggcctg gattgcaaaa
    53281 cagcgcgcgg aatattacgc cagcaatgat actgctccgg aacatcgcaa tgaaccggtg
    53341 cagcccatcc cgcaaaaact gcctaccgat gcgcaaaaag tggcgttggg ttttgcgctg
    53401 tatcacgatc cccgtttatc ggctgatagc accatttcat gcgctcattg ccatgcgttg
    53461 aatgcggggg gcgtcgatgg cagaaaaaca tcgattggtg ttggtggcgc agttgggccg
    53521 attaacgcgc cgacggtatt taactcagta tttaacgttg agcagttctg ggatggtcgt
    53581 gcggcaacat tgcaggatca ggctggtgga ccgccgttga acccgattga aatggcgtcg
    53641 aaatcctggg acgaaattat tgctaagctg gaaaaagatc cgcagcttaa aacgcagttc
    53701 ctcgaagtct atccgcaagg tttcagtggc gaaaatatta ctgatgccat tgctgaattt
    53761 gagaaaacat taattacgcc ggattcccca tttgataaat ggttgcgcgg agatgaaaat
    53821 gcgctgacgg cgcaacagaa aaaaggctat caattattta aagataataa atgtgcaact
    53881 tgtcatggtg gtattattct cggcggacgt tcctttgaac cgttggggct gaaaaaagac
    53941 tttaactttg gggaaattac ggcggcggat attggtcgta tgaatgtgac taaagaagag
    54001 cgtgataaat tgcgtcagaa agtacccggt ttacgtaacg ttgctttaac ggcaccgtac
    54061 ttccatcgcg gtgacgtgcc gacgctggac ggggcggtga aactgatgct gcgctatcag
    54121 gtaggcaaag agctgccgca ggaggatgtg gatgatatcg tagctttcct gcacagtctg
    54181 aacggggtgt acacgccgta tatgcaggat aaacaataat taatttgatc gcccgaacag
    54241 caatgtttgg gcgattttta ttacgataat aaagtctgtt tttaatatta tcatgttaaa
    54301 tgtttatatt ataaaaagtc gtttttctgc ttaggatttt gttatttaaa ttaagcctgt
    54361 aatgccttgc ttccattgcg gataaatcct acttttttat tgccttcaaa taaatttaag
    54421 gagttcgaaa tggaccagaa gctgttaacg gatttccgct cagaactact cgattcacgt
    54481 tttggcgcaa aggccatttc tactatcgcg gagtcaaaac gatttccgct gcacgaaatg
    54541 cgcgatgatg tcgcatttca gattatcaat gatgaattat atcttgatgg caacgctcgt
    54601 cagaacctgg ccactttctg ccagacctgg gacgacgaaa acgtccataa attgatggat
    54661 ttgtcgatca ataaaaactg gatcgacaaa gaagaatatc cgcaatccgc agccatcgac
    54721 ctgcgttgcg taaatatggt tgccgatctg tggcatgcgc ctgcgccgaa aaatggtcag
    54781 gccgttggca ccaacaccat tggttcttcc gaggcctgta tgctcggcgg gatggcgatg
    54841 aaatggcgtt ggcgcaagcg tatggaagct gcaggcaaac caacggataa accaaacctg
    54901 gtgtgcggtc cggtacaaat ctgctggcat aaattcgccc gctactggga tgtggagctg
    54961 cgtgagatcc ctatgcgccc cggtcagttg tttatggacc cgaaacgcat gattgaagcc
    55021 tgtgacgaaa acaccatcgg cgtggtgccg actttcggcg tgacctacac cggtaactat
    55081 gagttcccac aaccgctgca cgatgcgctg gataaattcc aggccgacac cggtatcgac
    55141 atcgacatgc acatcgacgc tgccagcggt ggcttcctgg caccgttcgt cgccccggat
    55201 atcgtctggg acttccgcct gccgcgtgtg aaatcgatca gtgcttcagg ccataaattc
    55261 ggtctggctc cgctgggctg cggctgggtt atctggcgtg acgaagaagc gctgccgcag
    55321 gaactggtgt tcaacgttga ctacctgggt ggtcaaattg gtacttttgc catcaacttc
    55381 tcccgcccgg cgggtcaggt aattgcacag tactatgaat tcctgcgcct cggtcgtgaa
    55441 ggctatacca aagtacagaa cgcctcttac caggttgccg cttatctggc ggatgaaatc
    55501 gccaaactgg ggccgtatga gttcatctgt acgggtcgcc cggacgaagg catcccggcg
    55561 gtttgcttca aactgaaaga
//
LOCUS       DAPHKZ010000017        53542 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.017, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000017 DAPHKZ010000000
VERSION     DAPHKZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 53542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53542
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.017"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(260..2092)
                     /locus_tag="RH288_001078"
     CDS             complement(260..2092)
                     /locus_tag="RH288_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV4030163.1"
                     /translation="MAEFELKALITGVDRLSPALSKMQKKIRGFKRQAEEASQGGLAL
                     GGGLAAGLTLSLKSYADQENAATGLKVAMMDANGEVGKSFQDINKLAIGLGNQLPGTT
                     ADFQNMMQMLVRQGIPAENILGGVGKATAYLAVQLKKTPEAAAEFAAKMQDATGTASE
                     DMMGLFDTIQKAFYLGVDDTNMLSFFTKTSSVLKMVNKDGLQAAQSLAPISVMMDQMG
                     MNGESAGNALRKVIQSGLSVKKIRDVNKVMARQKLGVQLDFTDGKGSFGGLDNMFRQL
                     AKLRKLTDVKRTGVLKAIFGDDAETLQVVNALIDKGKDGYDQIQQKMNKQASLNKRVQ
                     AQLGTLSNLWEAMTGTATNGLAAIGGAFSGDAKNITQWLGELGEKFTKFADENPRVIR
                     GVVGLAAGLAILKLGLMGVGSAISIVSRIMSMTPIGMIATAIALAAGLIITNWDVVGP
                     YFKKLWETIGPYFEAGWELLKKVFAWSPLGMVINNWGPVVKWFQDMWDKLKPIIEWFI
                     DSSGDTVDAINSAQWGAGAYDAYGTGIPPRGYTPYPEVDPAQANNASGATGPNPFMIN
                     KATAPKVDGEIKVSFINMPPGMRVTETRSSGIDINHDVGYTRFW"
     gene            complement(2234..2503)
                     /locus_tag="RH288_001079"
     CDS             complement(2234..2503)
                     /locus_tag="RH288_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HDV4030164.1"
                     /translation="MKELELKKPIIAHGETLSVLEFDEPIGKDVRELGYPYQMNQDES
                     VRLLAHVVSKYIVRLAKVPQSSVDQMSPADLNAAAWLVAGFFLQA"
     gene            complement(2503..2859)
                     /locus_tag="RH288_001080"
     CDS             complement(2503..2859)
                     /locus_tag="RH288_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDV4030165.1"
                     /translation="MARIGGTCYFKIDGQQLSLTGGIEVPMNRTVNDDIIGLDGSVDR
                     KETHRAPYVKGTFKVPKNFPVSKITSSDEMTITAELANGQVYVLSSAWLHGEANHNAE
                     EGTVDLEFHGEEGDYQ"
     gene            complement(2859..4355)
                     /locus_tag="RH288_001081"
     CDS             complement(2859..4355)
                     /locus_tag="RH288_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDV4030166.1"
                     /translation="MTISFNTIPSNTLVPLFYAEMDNQAANTAQDSGASLLIGHANNG
                     AEIVANSLVLMPSADYARQICGAGSQLARMVEAYRQTDPFGELYVIAVPESTGAAATV
                     TLTVTGEATESGTVNVYVGRTRVQAPVTNGDNVTTIASSIQDAINAVPTLPFTASSSA
                     GVVTLTARHKGLCGNEVPVSLNYYGFGGGEVLPAGVQIAVATGTAGTGAPVLTGAVAA
                     MADEPFDYIGLPFNDTASVNTLVTEMNDTSGRWSYARQLYGHVYTAKTGTLSELVNAG
                     DQFNQQHITLAGYEKETQTPADELAASRTARAAVFIRNDPARPTQTGELVGMLPAPKG
                     KRFTMTEQQTLLSHGVATAYVESGGLRIQRDVTTYRKNAYGVADNSYLDSETLHTSAY
                     VLRKLKSVITSKYGRHKLASDGTRFGPGQAIVTPAVIKGELLATYRQLERAGIVENYE
                     LFKQYLVVERDASDPNRLNTLFPPDYVNQLRVFAVVNQFRLQYSEESA"
     gene            complement(4339..4509)
                     /locus_tag="RH288_001082"
     CDS             complement(4339..4509)
                     /locus_tag="RH288_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000497758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2635 domain-containing protein"
                     /protein_id="HDV4030167.1"
                     /translation="MFVKPVKGRSVPDPARGDLLPAEGRNVDENNYWLRREAAGDIRR
                     VNKKVNTDDDKL"
     gene            complement(4518..5078)
                     /locus_tag="RH288_001083"
     CDS             complement(4518..5078)
                     /locus_tag="RH288_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030168.1"
                     /translation="MKLTPVIAALRARCPYFENRVAGAAQFKNLPEVGKLRLPAAYVV
                     PGDDSPGENKSQTDYWQELKEGFSVVVILSNGRDERGQFASYDVVDDVRQMLFKALLG
                     WNPEACGNPITYDGGTLLDLNRHELIYQFDFSVISELTEDDTRQQDELNSLDELRTLA
                     IDVDYLDPGNGPDGDIEHHTEITLPS"
     gene            complement(5075..5581)
                     /locus_tag="RH288_001084"
     CDS             complement(5075..5581)
                     /locus_tag="RH288_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001501060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030169.1"
                     /translation="MTTSFLHVDFQQPAEMRFNRARVRRAFVTIGQRHMRDARRLVMR
                     RARSAPGENPGYQTGRLARSIGYMVPRASKHRPGFMARIAPNQRNGEGNRRITGDFYP
                     AFLFYGVRRGAKRRRSHHRGASGGSGWRLAPRNNFMVETLEKNHSWTRYFLARELRKS
                     LKPERRHR"
     gene            complement(5556..5966)
                     /locus_tag="RH288_001085"
     CDS             complement(5556..5966)
                     /locus_tag="RH288_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDV4030170.1"
                     /translation="MKIRQAQTSATYILPDPGELNKRVLIRQRVDMPADNFGVEPQYP
                     VAFRTWAKVVQTSATTWQETAQTGDAITHYITIRYRRGITADYEVVWGDSVYRVKRQR
                     DLNGARRFLLLECTELGECRQSHGGNNDDFLFAR"
     gene            complement(5963..6286)
                     /locus_tag="RH288_001086"
     CDS             complement(5963..6286)
                     /locus_tag="RH288_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001492759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDV4030171.1"
                     /translation="MLLTMEEIKAQLRLDEDFDADDRHLQLLACAAQKRTETYLNRKL
                     YAPDETIPDSDPDGLHLPDDIRLGMLMLISHFYENRSSVTEVEKLDMPQSFGWLVGPY
                     RYFPQ"
     gene            complement(6289..6489)
                     /locus_tag="RH288_001087"
     CDS             complement(6289..6489)
                     /locus_tag="RH288_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030172.1"
                     /translation="MILKQDLKWSPDGMRVEVIRAGEYDDGALPARVQEIALQAGLAE
                     RGISAKSSKAAKEKKATTSKEG"
     gene            complement(6539..7744)
                     /locus_tag="RH288_001088"
     CDS             complement(6539..7744)
                     /locus_tag="RH288_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDV4030173.1"
                     /translation="MAVDIKDVEQVAQELQQKFDDFKAKNDKRVDAIEQEKGKLAGQV
                     ETLNGKLSELENLKSDLEKELLELKRPAGGAQNKLATEHKEAFVGFLRKGREDGLRDL
                     ERKALQVGTDEDGGYAVPEALDRNILTLLKDEVVMRQEATVITVGGSDYKKLVNLGGT
                     ASGWVGETDARSQTATSKLGLIEPFMGEIYGNPQATQKMLDDAFFNVEAWINSELATE
                     FAEQEEIAFTTGDGTKKPKGFLAYESTDETDKVRAFGKLQHIVSGEATAVTADAIIKL
                     IYTLRKAHRTGAKFMMNNNSLFAIRLLKDSEGNYLWRPGLELGQPSSLAGYGIAENEQ
                     MPDIAADAKAIAFGNFKRGYTIVDRIGTRILRDPYTNKPFVGFYTTKRTGGMLVDSQA
                     IKLLKIAAA"
     gene            complement(7759..8409)
                     /locus_tag="RH288_001089"
     CDS             complement(7759..8409)
                     /locus_tag="RH288_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HDV4030174.1"
                     /translation="MQTKQRLDVPLSLKSVSDSGEFEGYGSVFGVKDSHDDVVMSGAF
                     AASLRAWSDRKALPALLWQHRMDEPIGVYTEMKEDDVGLYVRGRLLIDDDPLAKRAHA
                     HMKAGSLTGLSIGYVLKDWEYDRSKEAFLLKEIDLWEVSLVTFPSNDEARISDVKNAL
                     ARGEIPEQKKIERVLRDVGLSRTQAKAFMAGGYGALSLRDAEDVGSALNALKNLNF"
     gene            complement(8387..9628)
                     /locus_tag="RH288_001090"
     CDS             complement(8387..9628)
                     /locus_tag="RH288_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV4030175.1"
                     /translation="MFFSGLFQRKSDAPVTTPAELADAIGLSYDTYTGKQISSQRAMR
                     LTAVFSCVRVLAESVGMLPCNLYHLNGNLKQRATGERLHKLISTHPNGYMTPQEFWEL
                     VVTCLCLRGNFYAYKVKAFGEVAELLPVDPGCVVPKLNSSWEPVYQVTFPDGSTDVLS
                     QEDIWHVRTLTLDGLVGLNPIAYAREAISLAAATEEHGARLFSNGAVTSGVLRTEQTL
                     SDQAYERLKKDFEERHTGLGNAHRPMILEMGLDWKSMALNAEDSQFLETRKFQLEEIC
                     RLFRVPLHMVQNTDRATFNNIEELGLGFINYSLVPYLTRIEQRINTGLVRKSKQGVYY
                     AKFNAGALLRGDMKSRFEAYATGINWGIYSPNDCRDLEDMNPRPGGDVYLTPMNMTTK
                     PSDGSKAGKQKDNANADETTS"
     gene            complement(9628..9810)
                     /locus_tag="RH288_001091"
     CDS             complement(9628..9810)
                     /locus_tag="RH288_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030176.1"
                     /translation="MIMLILAPLVGVLGALLLAYGAWLIYPPAGFVVAGALCLFWSWL
                     VARYLDRTQSSVCGGK"
     gene            complement(9822..11318)
                     /locus_tag="RH288_001092"
     CDS             complement(9822..11318)
                     /locus_tag="RH288_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDV4030177.1"
                     /translation="MPITLEPWQLFVICCAFGWVNKGSRLRRFREVYTEIPRKNGKSA
                     ISAGVALYCFACDNEFGAEVYSGATTEKQAWEVFRPARLMCKRTPMLTEAFGIEVNAS
                     NMNRPEDGARFEPLIGNPGDGSSPHCAVVDEYHEHATDALYTTMLTGMGARRQPLMWA
                     ITTAGYNIEGPCYDKRREVIEMLNGSVPNDELFGIIYTVDEGDDWTDPQVLEKANPNI
                     GVSVYREFLLSQQQRAKNNARLANVFKTKHLNIWVSARSAYFNLVSWQSCEDKSLTLE
                     QFEGQPCILAFDLARKLDMNSMARLYTREIDGKTHYYSVAPRFWVPYDTVYSVEKNED
                     RRTAERFQKWVEMGVLTVTDGAEVDYRYILEEAKAANKISPVSESPIDPFGATGLSHD
                     LADEDLNPITIIQNYTNMSDPMKELEAAIESGRFHHDGNPIMTWCIGNVVGKTIPGND
                     DVVKPVKEQAENKIDGAVALIMAVGRAMLYEKEDTLSDHIESYGIRSL"
     gene            complement(11552..12046)
                     /locus_tag="RH288_001093"
     CDS             complement(11552..12046)
                     /locus_tag="RH288_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HDV4030178.1"
                     /translation="MAGTAGRSGRRPKPTARKALAGNPGKRALNKDEPVFTPIKGVEP
                     PEWFAEEDLPLATIMWQLTTKELCGQGLLCVTDLAVLERWCVAYEFWRRAVKNIARQG
                     NTITGAMGGMVKNPELTAKKEQESEMSSTGAMLGLDPSSRQRLIGLAGQKKATNPFLK
                     IIES"
     gene            complement(12172..12522)
                     /locus_tag="RH288_001094"
     CDS             complement(12172..12522)
                     /locus_tag="RH288_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDV4030179.1"
                     /translation="MPSRIPKACRVRGCRHTTTDPSGYCESHKSEGWKQYKPGQSRHQ
                     RGYGSKWGVIRVRVLKRDKGLCQLCLRAGVVREAKTVDHIIPKAHGGSDADSNLQSLC
                     WPCHKAKTARERLK"
     gene            13048..13341
                     /gene="iss"
                     /locus_tag="RH288_001095"
     CDS             13048..13341
                     /gene="iss"
                     /locus_tag="RH288_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="increased serum survival lipoprotein Iss"
                     /protein_id="HDV4030180.1"
                     /translation="MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVS
                     GIGQEKTVDAAKICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ"
     gene            complement(13432..13614)
                     /gene="rzoD"
                     /locus_tag="RH288_001096"
     CDS             complement(13432..13614)
                     /gene="rzoD"
                     /locus_tag="RH288_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage lysis lipoprotein RzoD"
                     /protein_id="HDV4030181.1"
                     /translation="MRKLKMMLCVMMLPLVVVGCTSKQSVSQCVKPPPPPAWIMQPPP
                     DWQTPLNGIISPSERG"
     gene            complement(13831..14328)
                     /gene="rrrD"
                     /locus_tag="RH288_001097"
     CDS             complement(13831..14328)
                     /gene="rrrD"
                     /locus_tag="RH288_001097"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme RrrD"
                     /protein_id="HDV4030182.1"
                     /translation="MPPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVSYIPYKD
                     IVGVWTVCHGHTGKDIMLGKTYTKAECKALLNKDLATVARQINPYIKVDIPETTRGAL
                     YSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREIC
                     LWGQQ"
     gene            complement(14328..14543)
                     /gene="essD"
                     /locus_tag="RH288_001098"
     CDS             complement(14328..14543)
                     /gene="essD"
                     /locus_tag="RH288_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HDV4030183.1"
                     /translation="MKSMDKLTTGVAYGTSAGSAGYWFLQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDKRKAARGE"
     gene            15133..16230
                     /gene="ompC"
                     /locus_tag="RH288_001099"
     CDS             15133..16230
                     /gene="ompC"
                     /locus_tag="RH288_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HDV4030184.1"
                     /translation="MKKLTVAISAVAASVLMAMSAQAAEIYNKDSNKLDLYGKVNAKH
                     YFSSNDADDGDTTYARLGFKGETQINDQLTGFGQWEYEFKGNRAESQGSSKDKTRLAF
                     AGLKFGDYGSIDYGRNYGVAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNN
                     DFFGLVDGLNFAAQYQGKNDRSDFDNYTEGNGDGFGFSATYEYEGFGIGATYAKSDRT
                     DTQVNAGKVLPEVFASGKNAEVWAAGLKYDANNIYLATTYSETQNMTVFADHFVANKA
                     QNFEAVAQYQFDFGLRPSVAYLQSKGKDLGVWGDQDLVKYVDVGATYYFNKNMSTFVD
                     YKINLLDKNDFTKALGVSTDDIVAVGLVYQF"
     gene            complement(16420..16803)
                     /gene="quuD"
                     /locus_tag="RH288_001100"
     CDS             complement(16420..16803)
                     /gene="quuD"
                     /locus_tag="RH288_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein QuuD"
                     /protein_id="HDV4030185.1"
                     /translation="MRDIQMVLERWGAWAANNHEDVTWSSIAAGFKGLITSKVKSRPQ
                     CCDDDAMIICGCMARLKKNNSDLHDLLVDYYVVGMTFMSLAGKHCCSDGYIGKRLQKA
                     EGIIEGMLMALDIRLEMDIVVNNSN"
     gene            complement(16889..17029)
                     /locus_tag="RH288_001101"
     CDS             complement(16889..17029)
                     /locus_tag="RH288_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcG family protein"
                     /protein_id="HDV4030186.1"
                     /translation="MMFESYMAERLRRRWVRLRLYRFPGSVLTDYRILKNYAKTLTGA
                     GV"
     gene            complement(17026..17388)
                     /gene="rusA"
                     /locus_tag="RH288_001102"
     CDS             complement(17026..17388)
                     /gene="rusA"
                     /locus_tag="RH288_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RusA"
                     /protein_id="HDV4030187.1"
                     /translation="MNTYHITLPWPPSNNRYYRHNRGRTHISAEGQAYRDNVTRIIKN
                     AMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKM
                     PVTKGGRLELTITEMGNE"
     gene            complement(17385..17675)
                     /locus_tag="RH288_001103"
     CDS             complement(17385..17675)
                     /locus_tag="RH288_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HDV4030188.1"
                     /translation="MADLRKAARGRECQVRITGVCNGNPETSVLAHIRLAGLCGTGIK
                     PPDLIATIACSACHDEIDRRTHFVDAEYAKECALEGMARTQVIWLKEGVIKA"
     gene            complement(17668..17838)
                     /locus_tag="RH288_001104"
     CDS             complement(17668..17838)
                     /locus_tag="RH288_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030189.1"
                     /translation="MATPLIRVMNGHIYRVPNRRKRKPELKPSEIPTLLGYTASLVDK
                     KWLRLAARRNHG"
     gene            complement(17838..18293)
                     /gene="ybcN"
                     /locus_tag="RH288_001105"
     CDS             complement(17838..18293)
                     /gene="ybcN"
                     /locus_tag="RH288_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA base-flipping protein YbcN"
                     /protein_id="HDV4030190.1"
                     /translation="MNLPQDGIKLHRGNFTAIGQQIQPYLEDGKCFRMVLKPWREKRS
                     LSQNALSHMWYSEISEYLISRGKSFATAAWVKDALKHTYLGYETKDLVDVVTGEITTI
                     QSLRHTSDLDTGEMYVFLCKVEAWAMNIGCHLTIPQSCEFQLLRDKQEA"
     gene            complement(18290..18391)
                     /locus_tag="RH288_001106"
     CDS             complement(18290..18391)
                     /locus_tag="RH288_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030191.1"
                     /translation="MRTYNPNSLLPSQMQKCTCDFLHPASDLCGGEA"
     gene            complement(18484..18936)
                     /locus_tag="RH288_001107"
     CDS             complement(18484..18936)
                     /locus_tag="RH288_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004102406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030192.1"
                     /translation="MKRLFVIAPLLVLVGCAQNISPNSYSVGSVGMVNRTIAGTVISA
                     RGVDISGTSALGGTAGAAVGATAGSALGGGVRSNIVGAVGGAVIGGIAGAAIESSATK
                     QTGMEYVVETENGNLMTIVQGKDPLFTQGSKVLVLYGNPSRIITDPRH"
     gene            complement(18933..19493)
                     /locus_tag="RH288_001108"
     CDS             complement(18933..19493)
                     /locus_tag="RH288_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine acyltransferase"
                     /protein_id="HDV4030193.1"
                     /translation="MKKIILLAMIIGSLTGCASVPPLNFSTPNVGVSQKKIDAEIKSL
                     TVSLARPDEQKGDITAGMEAITPIWRESLQEALDRMTIFRDSSPNTVSLNVKVLALDV
                     PAFGVSMTTKAIARYEIINRANGDIIYTQDIESTGTVPASYAFYGIVRARESVNRAVQ
                     NNITQFLQALESVDLSRPMFPVRVAK"
     gene            complement(19979..20272)
                     /locus_tag="RH288_001109"
     CDS             complement(19979..20272)
                     /locus_tag="RH288_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HDV4030194.1"
                     /translation="MTGKEAIIHYLGTHKSFCAQDVAAVTGATVTSINQAAAKMARTG
                     ILVIDGKVWRTVYYRFATKEEREGKVSTNLIFKECRQSAAMKRVLAFYRGNFQ"
     gene            complement(20269..20970)
                     /locus_tag="RH288_001110"
     CDS             complement(20269..20970)
                     /locus_tag="RH288_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication protein P"
                     /protein_id="HDV4030195.1"
                     /translation="MKNIAAQMINFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVF
                     SQLLATFPASLANRDQNELNEIRRQWVLAFRENGITTMEQVNAGMRVARRQNRPFLPS
                     PGQFVAWCREEASVTAGLPNASELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
                     YQNMRANALTDSELRRKAADELAHMTARINRGEAIPEPVKQLPVMGGRPLNRAQALTK
                     IAEIKAKFGLKGASV"
     gene            complement(20967..21986)
                     /locus_tag="RH288_001111"
     CDS             complement(20967..21986)
                     /locus_tag="RH288_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDV4030196.1"
                     /translation="MTGSEMAKVGLREQNRLSGANRNTLIAGGIMANTAEIFNFPVPD
                     AAQKEPRVADLDDGYTRIANELLEAVMLAGLTQHQLLVFLAVMRKTYGFNKKLDWVSN
                     EQLSELTGILPHKCSAAKSVLVKRGILIQSGRNIGINNVVSEWATLPESGKKNKVYLK
                     EVNLPESGKKSLPKSGKGVYPNQVNTKDKLTKDNIKPFSSENSGESSDQPENDLPVVK
                     PDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFAGWANDIRLMRERDGRNHR
                     DMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQAGVTAGKPKLDLTNTDWI
                     YGVDL"
     gene            complement(21983..22522)
                     /locus_tag="RH288_001112"
     CDS             complement(21983..22522)
                     /locus_tag="RH288_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin YdaT domain-containing protein"
                     /protein_id="HDV4030197.1"
                     /translation="MQPLTYQQTSGFIPTAVINRSQIKQVPGHEKIRDAIRAWSAVDN
                     QDVVAALIVNEYRAQGGGTIDFPDDVSRARQKLFRFLDNKFDSEKYRNNVRELTPAIL
                     AVLPLKYRGHLVEQDSFMARLAEMEKELSEAKQAVILNAPRHQKLKEMSEGIVSMFRV
                     DPDLAGPLMAMVTTMLGAI"
     gene            complement(22553..22780)
                     /locus_tag="RH288_001113"
     CDS             complement(22553..22780)
                     /locus_tag="RH288_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV4030198.1"
                     /translation="MTNQTIQLAISITGSQKRLADLCGVAQPTVWRWLHGGGIDARYV
                     MKIVSATGGKIKPADIRPDLAPLFNASNSAA"
     gene            22891..23583
                     /locus_tag="RH288_001114"
     CDS             22891..23583
                     /locus_tag="RH288_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001337214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV4030199.1"
                     /translation="MKKETLADRLNLAMEQSGMSQGALAKASGVAQPTIWRLTSGNAR
                     GSTKIVEIANALGVRTEWLSSGIGPMRNDGQQSGKPAVSHSKYFKIDVLDIEVSAGPG
                     VINREFVEVLRSVEYSFDDARHMFDGRKAENIRIINVRGDSMSGTIEPGDLLFVDITV
                     KSFDGDGIYAFLYDDTAHVKRLQMMKDKLLVISDNKSYSPWDPIEKDEMNRVFIFGKV
                     IGSMPQTYRKHG"
     gene            23665..24138
                     /locus_tag="RH288_001115"
     CDS             23665..24138
                     /locus_tag="RH288_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030200.1"
                     /translation="MEKPSFPPLLTAGFHDMDSDGIKSLCVDTFPKSVRRSMLYCNFI
                     QLIEQFKLVNQQCLCFSEVWIDGSFTTEKPEPDDIDILVVVDYLALNSLPNTLMPLVS
                     SLLNRDFIKENYSIDVLLLPENHPEIDYSERRSYWRGWFGFDRKENPKGLVRVML"
     gene            24135..25067
                     /locus_tag="RH288_001116"
     CDS             24135..25067
                     /locus_tag="RH288_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030201.1"
                     /translation="MSEEKTFNSLKERIAFIQRDVDLLAQNKGRSFADDIIFRSLDSH
                     LSDLRERQRAIDNQHPLRDFMELRLKGVLVDFGSIPLDILSVISGNLASLVQKAVYRL
                     GSGKDSSRVPIDVKKSLDMRLADLRPGSTKLGVTFSTGSCELIETVSSHAVKEIFALL
                     SSIDEETFTAKIAEIGSQSTANLKNIINECEKYSLNFDLTWIGPLSDGTRQVSISSED
                     IKKLNARLALTKVIQLPDEHISGELAILSMYGKLEIASELGKIKASYPIDMLGEIQSK
                     YKVGERISLVVSVSEIHNERLGTSRRNYMVKKIE"
     gene            25552..25758
                     /locus_tag="RH288_001117"
     CDS             25552..25758
                     /locus_tag="RH288_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor protein"
                     /protein_id="HDV4030202.1"
                     /translation="MVHQHYGTQTVNRGAVMPGMLVKHKDGTWTASANLRGRLYLHRG
                     IERTYTRDLLVEVFLDGRGNGLNH"
     gene            25834..26130
                     /locus_tag="RH288_001118"
     CDS             25834..26130
                     /locus_tag="RH288_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor protein Gam"
                     /protein_id="HDV4030203.1"
                     /translation="MNAYYIQDRLEAQSWARHYQQIAREEKEAELADDMEKGLPQHLF
                     ESLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHIRYMVETIARHQVDIDSEV"
     gene            26136..26921
                     /gene="bet"
                     /locus_tag="RH288_001119"
     CDS             26136..26921
                     /gene="bet"
                     /locus_tag="RH288_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HDV4030204.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCA
                     RLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDD
                     DLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKAAEQKVAA"
     gene            26918..27598
                     /locus_tag="RH288_001120"
     CDS             26918..27598
                     /locus_tag="RH288_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HDV4030205.1"
                     /translation="MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKP
                     RSGKKWPDMKMSYFHTLLAEICTGVAPEVNAKALAWGKQYENDARALFEFTSGVNVTE
                     SPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQY
                     SMWVTRKDAWYFANYDPRMKREGLHYVVIERNEKYMANFDEMVPEFIEKMDVALAEIG
                     FVFGEQWR"
     gene            27595..27753
                     /locus_tag="RH288_001121"
     CDS             27595..27753
                     /locus_tag="RH288_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1317 family protein"
                     /protein_id="HDV4030206.1"
                     /translation="MKHPHDNIRVGAITFVYSVTKRGWVFPGLSVIRNPLKAQRLAEE
                     INNKRESV"
     gene            27750..28502
                     /locus_tag="RH288_001122"
     CDS             27750..28502
                     /locus_tag="RH288_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030207.1"
                     /translation="MIHFHGGPITPDTCALKAWKGRHAFISFANPAQIDLASEVTQSF
                     ALDNGAFTFWTKNKAVDWNEYYRFVERWGNHPRFSFAVIPDVIGGTSEENDALIAAWP
                     HGKFIGAPVWHMNEPDERFIRLCHEFPRVCIGSMGEYDAKRPRACRAKLRDLIRHVVD
                     QYGYPITKIHGLRMLNKDIFTHVPLSSADSTNVARNIGIDKSWVGSPYAPASKETRTQ
                     VLVERIESFNSASSLNYNAERDVFTPQLAFEV"
     gene            28510..28725
                     /locus_tag="RH288_001123"
     CDS             28510..28725
                     /locus_tag="RH288_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDV4030208.1"
                     /translation="MTIEHNNALRSIARQANYEIKKARQQFPDKNVNDICRSVLKKHR
                     ETVTLMGFTPTHLSLAIGMLNGVFKER"
     gene            28824..29042
                     /locus_tag="RH288_001124"
     CDS             28824..29042
                     /locus_tag="RH288_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HDV4030209.1"
                     /translation="MADIIDSASEIEELQRNTAIKMRRLNYQTVSATHCCECGDPIDE
                     RRRLAVQGCRTCASCQEEIELKNKQWGL"
     gene            29090..29368
                     /locus_tag="RH288_001125"
     CDS             29090..29368
                     /locus_tag="RH288_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HDV4030210.1"
                     /translation="MFRIIFPNTWYVDHHGTPCKILRSTHNKVHYIRKGRTCIASMFR
                     FNHDFEPVNKADADRIAVEIETAEHIKKLRDMRSKSRGNHGIIQPHTR"
     gene            29567..30730
                     /locus_tag="RH288_001126"
     CDS             29567..30730
                     /locus_tag="RH288_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDV4030211.1"
                     /translation="MSLFRRSEIWYASFTLPNGKRFKQSLGTKDKRQATELHDKLKAE
                     AWRVSKLGEIPDMTFEEACVRWLEEKAHKKSLDDDKSRIGFWLQHFAGMQLRDITESK
                     IYSAMQKMTNRRHEENWKLRAEACRKKGKPVPEYTPKPASVATKATHLSFIKALLRAA
                     EREWKMLDKAPIIKVPQPKNKRIRWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSN
                     IINLEWQQIDMQRRVAWINPEESKSNRAIGVALNDTACRVLKKQIGNHHRWVFVYKES
                     CTKPDGTKAPTVRKMRYDANTAWKAALRRAGIDDFRFHDLRHTWASWLVQAGVPLSVL
                     QEMGGWESIEMVRRYAHLAPNHLTEHARQIDSILNPSVPNLSQSKNKEGTNDV"
     gene            complement(30745..30820)
                     /locus_tag="RH288_001127"
     tRNA            complement(30745..30820)
                     /locus_tag="RH288_001127"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30785..30787),aa:Thr,seq:cgt)
     gene            complement(30935..32188)
                     /gene="proA"
                     /locus_tag="RH288_001128"
     CDS             complement(30935..32188)
                     /gene="proA"
                     /locus_tag="RH288_001128"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDV4030212.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            complement(32200..33303)
                     /gene="proB"
                     /locus_tag="RH288_001129"
     CDS             complement(32200..33303)
                     /gene="proB"
                     /locus_tag="RH288_001129"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDV4030213.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            33591..34646
                     /gene="phoE"
                     /locus_tag="RH288_001130"
     CDS             33591..34646
                     /gene="phoE"
                     /locus_tag="RH288_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HDV4030214.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     gene            complement(34685..35086)
                     /gene="crl"
                     /locus_tag="RH288_001131"
     CDS             complement(34685..35086)
                     /gene="crl"
                     /locus_tag="RH288_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HDV4030215.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(35144..36388)
                     /gene="frsA"
                     /locus_tag="RH288_001132"
     CDS             complement(35144..36388)
                     /gene="frsA"
                     /locus_tag="RH288_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HDV4030216.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            complement(36480..36938)
                     /gene="gpt"
                     /locus_tag="RH288_001133"
     CDS             complement(36480..36938)
                     /gene="gpt"
                     /locus_tag="RH288_001133"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDV4030217.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            37199..38656
                     /gene="pepD"
                     /locus_tag="RH288_001134"
     CDS             37199..38656
                     /gene="pepD"
                     /locus_tag="RH288_001134"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HDV4030218.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDAL
                     KSLVNTYQDILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIKSVGHYWTLLTELLKEIPAK"
     gene            complement(38713..39234)
                     /locus_tag="RH288_001135"
                     /pseudo
     CDS             complement(38713..39234)
                     /locus_tag="RH288_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
     gene            complement(39233..39436)
                     /locus_tag="RH288_001136"
                     /pseudo
     CDS             complement(39233..39436)
                     /locus_tag="RH288_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706235.2"
                     /note="mutations in this gene result in a compromised
                     ability for drug-inducible mexXY expression; expression is
                     inducible by the same ribosome-targeting agents that
                     induce mexXY; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
     gene            complement(39682..40134)
                     /locus_tag="RH288_001137"
     CDS             complement(39682..40134)
                     /locus_tag="RH288_001137"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV4030219.1"
                     /translation="MNNIQIRDYQPGDFQQLCAIFIRAVTMISSQHYSPQQIAAWAQI
                     DESRWKEKLAKSQVRVAVINAQPVGFITCVERYIDMLFVDPEYTRRGVACALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGTWFTNFYMRYKPQY"
     gene            complement(40144..40542)
                     /gene="yafO"
                     /locus_tag="RH288_001138"
     CDS             complement(40144..40542)
                     /gene="yafO"
                     /locus_tag="RH288_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafO"
                     /protein_id="HDV4030220.1"
                     /translation="MRVFKTKLIRLQLTAEELDALTADFISYKRDGVLPDIFGRDALY
                     DDSFTWPLIKFERVAHIHLANVNNPFPPQLRQFSRTNDEAHLVYCQGAFDEQAWLLIA
                     ILKPEPHKQARDNNQMHKIGKMAEAFRMRF"
     gene            complement(40545..40838)
                     /gene="yafN"
                     /locus_tag="RH288_001139"
     CDS             complement(40545..40838)
                     /gene="yafN"
                     /locus_tag="RH288_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system antitoxin YafN"
                     /protein_id="HDV4030221.1"
                     /translation="MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSAS
                     AFEALMDMLAEQEEKKPIKARFRPSAARLEEITRRAEKYLNDMTDDDFNDFKE"
     gene            complement(40890..41945)
                     /gene="dinB"
                     /locus_tag="RH288_001140"
     CDS             complement(40890..41945)
                     /gene="dinB"
                     /locus_tag="RH288_001140"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDV4030222.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            complement(42016..42801)
                     /gene="lafU"
                     /locus_tag="RH288_001141"
     CDS             complement(42016..42801)
                     /gene="lafU"
                     /locus_tag="RH288_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HDV4030223.1"
                     /translation="MTTIKLIVNSVSKSERESIIAALHGQSIFSGGGLSPLNKISPSH
                     PPKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEME
                     IVPQGLRVLIKDDQNRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMA
                     YKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDAKNPQSAGNRRI
                     EIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            42773..44485
                     /locus_tag="RH288_001142"
                     /pseudo
     CDS             42773..44485
                     /locus_tag="RH288_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140833.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
     gene            complement(44709..45206)
                     /gene="rayT"
                     /locus_tag="RH288_001143"
     CDS             complement(44709..45206)
                     /gene="rayT"
                     /locus_tag="RH288_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="REP-associated tyrosine transposase RayT"
                     /protein_id="HDV4030224.1"
                     /translation="MSEYRRYYIKGGTWFFTVNLRNRRSQLLTTQYQMLRHAIIKVKR
                     DRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHA
                     IRNTKDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVARGLYPIDWAGDVTDFSAG
                     ERIIS"
     gene            complement(45382..46131)
                     /locus_tag="RH288_001144"
     CDS             complement(45382..46131)
                     /locus_tag="RH288_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDV4030225.1"
                     /translation="MSLPSIPSFVLSGLLLICLPFSSFASATTSHISFSYAARQRMQN
                     RARLLKQYQTHLKKQASYIVEGNAESKRALRQHNQEQIKQHPEWFPAPLKASDRRWQA
                     LAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVFYAYNKILE
                     AKLPRTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRT
                     GETIRISRLAEPFWQDHFLGARRILTEETIL"
     gene            46341..46601
                     /gene="dinJ"
                     /locus_tag="RH288_001145"
     CDS             46341..46601
                     /gene="dinJ"
                     /locus_tag="RH288_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin DinJ"
                     /protein_id="HDV4030226.1"
                     /translation="MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVARE
                     KALPFDLREPNQLTIQSIKNSEAGIDVHKAKDADDLFDKLGI"
     gene            46604..46882
                     /gene="yafQ"
                     /locus_tag="RH288_001146"
     CDS             46604..46882
                     /gene="yafQ"
                     /locus_tag="RH288_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafQ"
                     /protein_id="HDV4030227.1"
                     /translation="MIQRDIEYSGQYSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLP
                     AVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG"
     gene            47038..47778
                     /locus_tag="RH288_001147"
     CDS             47038..47778
                     /locus_tag="RH288_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HDV4030228.1"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     gene            complement(47749..48516)
                     /locus_tag="RH288_001148"
     CDS             complement(47749..48516)
                     /locus_tag="RH288_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HDV4030229.1"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     gene            complement(48722..49300)
                     /gene="lpcA"
                     /locus_tag="RH288_001149"
     CDS             complement(48722..49300)
                     /gene="lpcA"
                     /locus_tag="RH288_001149"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HDV4030230.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            49540..51984
                     /gene="fadE"
                     /locus_tag="RH288_001150"
     CDS             49540..51984
                     /gene="fadE"
                     /locus_tag="RH288_001150"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HDV4030231.1"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALVKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     gene            complement(52027..52473)
                     /gene="ivy"
                     /locus_tag="RH288_001151"
     CDS             complement(52027..52473)
                     /gene="ivy"
                     /locus_tag="RH288_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308274.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ivy family C-type lysozyme inhibitor"
                     /protein_id="HDV4030232.1"
                     /translation="MFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQG
                     HKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFS
                     TIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     gene            52654..53424
                     /gene="yafV"
                     /locus_tag="RH288_001152"
     CDS             52654..53424
                     /gene="yafV"
                     /locus_tag="RH288_001152"
                     /EC_number="3.5.1.111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutaramate amidase"
                     /protein_id="HDV4030233.1"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMAALREYREKFPAWQDADEFRLW"
BASE COUNT        13229 a        13921 c        13043 g        13349 t
ORIGIN      
        1 ctttgcactt atcaatttat tttctttata aacatcacca agttttatgg ctcctccaga
       61 taactgaata atatgttcat ctttaaagga gatgttgcca gagattatga gagatgaaaa
      121 aatagccgct actccaagaa ttacacttgc tgtgatatag cctttcattt ttcgcctatt
      181 aacatttttc taaatgtgca ttaattctat cactctattt atgacttaca accagcaata
      241 cctgtgaggg gaatcctggc taccaaaatc gggtatagcc aacatcgtga tttatatcaa
      301 tgccactgga gcgtgtttcc gtaacccgca tacctggtgg catatttata aatgatacct
      361 tgatctcacc atcaactttt ggcgcggtag ctttattaat catgaaggga ttcggacctg
      421 tggcaccgga ggcgttgttt gcctgagccg gatccacctc cggataagga gtgtatcccc
      481 gtggcggtat tcccgtccca taagcatcat aagcacccgc gccccactgc gcagagttaa
      541 tggcatcgac cgtgtcaccg gaactgtcga taaaccactc aataattggc ttcagcttgt
      601 cccacatatc ctgaaaccac ttaacaaccg gcccccagtt attgatcacc atccccagcg
      661 gcgaccaggc aaaaactttc ttaaggagtt cccagccagc ctcaaaataa ggaccaatgg
      721 tttcccagag cttcttgaaa taaggtccga caacatccca gttggtgata attaatcccg
      781 cagccagggc tatcgccgtc gcaatcatgc caatcggcgt catcgacatg atcctgctga
      841 caatgctgat ggcactgccc acgcccatca atcccagttt cagaatcgca agaccggcag
      901 caagcccgac gacgccgcga ataacccggg gattttcatc cgcaaacttc gtgaatttct
      961 cccccaactc ccccagccac tgcgtgatgt tcttagcgtc accagaaaat gcgccgccaa
     1021 tagccgcaag gccgttagtt gcggtccccg tcattgcctc ccacaggttg gacagcgtac
     1081 caagctgagc ctgaacacgt ttattcaggc tggcctgttt attcatcttc tgctggatct
     1141 gatcgtagcc atcctttcct ttatcgatca gcgcattgac cacctgaagg gtttcggcat
     1201 catcaccaaa tattgcctta agtacgcctg ttcgcttaac gtcggtcagt tttcgcaact
     1261 ttgccagttg cctgaacatg ttatcaagac cgccaaaact tcctttgccg tcagtaaaat
     1321 cgagctgtac cccgagtttc tggcgggcca tgactttatt gacgtccctg attttcttaa
     1381 cgcttaatcc ggactggata acttttcgca gggcattacc tgccgactcc ccgttcatcc
     1441 ccatctgatc catcatgaca ctgatggggg caagactctg tgcagcctga agaccgtcct
     1501 tattcaccat cttcagaaca gagctggttt tagtgaagaa tgacagcatg ttggtgtcgt
     1561 caacgcccag ataaaacgcc ttctgaattg tgtcgaacag ccccatcatg tcttctgagg
     1621 ccgttccggt agcatcctgc atctttgcgg caaactcggc agccgcttcc ggtgtttttt
     1681 tcagttgtac cgcaagataa gctgtcgctt tacccacacc acccagaatg ttttctgccg
     1741 ggatcccctg acgcaccagc atctgcatca tgttctggaa atcagccgtt gtaccgggta
     1801 gctggttacc caggccaata gccagtttat tgatgtcctg gaagctcttt ccaacctcgc
     1861 cgttcgcatc catcatggcg actttcagcc cggtagcggc gttttcctga tcggcataag
     1921 atttcaggga aagcgtcagc cccgctgcca gtccgccacc aagcgccagc ccaccctgtg
     1981 acgcttcttc cgcctggcgt ttaaatcccc ggattttctt ttgcattttc gacagcgcgg
     2041 gagaaagcct gtcgacaccg gtgatcaacg ccttaagctc aaattcagcc atgtgtgcgt
     2101 ttctcctgct ctatcctgtt tgcctgactg accagcaagg gaatttcact gatcggcata
     2161 ttcagcaatt cgaagggatt aatgcgccag tagctggcgc agtcaaagaa gcgatcagtg
     2221 aggtattcag ccgtcaggcc tggaggaaaa aaccagccac aagccacgcc gctgcattca
     2281 ggtctgccgg agacatctgg tcgacagagc tttgcggcac tttcgccagc cgcacaatgt
     2341 atttcgacac cacatgcgcc agaagtctga cggactcatc ctgattcatc tggtagggat
     2401 accccagctc gcggacatcc ttcccgatgg gttcatcaaa ctccagtacg gagagtgtct
     2461 caccatgagc gataatcggt ttctttaact caagctcttt cattactggt aatccccttc
     2521 ttcaccgtgg aactcaagat caaccgtgcc ttcttcggca ttatggttcg cttcgccgtg
     2581 cagccaggcg gacgacaata catagacctg accgttcgcc agctcggcag tgatggtcat
     2641 ctcatcagac gaggtgattt tgctcaccgg aaaattcttc ggcaccttga aggtcccttt
     2701 gacataaggc gcacggtgag tttccttgcg gtccactgaa ccgtccaggc cgatgatgtc
     2761 atcattgacc gtcctgttca tgggcacctc aatgccgccg gtcagcgata gctgctgacc
     2821 gtcaattttg aaataacagg ttcccccgat acgggccatt atgcagactc ctctgaatac
     2881 tgaagacgga actggttaac cacggcaaaa acacgcaact ggttaacata gtcaggcggg
     2941 aacagcgtgt tcaggcggtt cggatcgctg gcatcacgct caacaaccag gtactgctta
     3001 aacagttcgt agttttccac gatccccgca cgctcaagct gacggtaggt tgccagcagt
     3061 tcccctttga ttaccgccgg ggtgacaatc gcctgaccgg gaccaaagcg ggtaccgtcg
     3121 ctggcaagct tgtgacgccc gtacttactg gtaatgacgg atttcagttt gcgcagtaca
     3181 tacgcactgg tatgcagcgt ctcgctgtcg aggtagctgt tatccgcaac cccgtaagca
     3241 tttttcctgt acgtggtgac atcacgctga atgcgcagcc ccccgctttc gacatacgcc
     3301 gttgccacgc catgagacag cagggtctgc tgctcggtca tcgtgaaccg tttccccttc
     3361 ggcgcaggca gcatccccac cagctcaccg gtctgcgtgg gacgtgccgg atcgttgcgg
     3421 ataaacaccg ctgcgcgggc ggtacggctt gccgccagct cgtcggcagg cgtctgggtc
     3481 tctttttcgt accccgccag ggtgatgtgc tgctggttaa actggtcacc tgcgttcacc
     3541 agttctgaca gtgtgccggt ctttgccgta tacacatgac catacagctg acgcgcatag
     3601 ctccagcgac cgctggtatc gttcatctcg gtcaccagcg tgttaacgga ggccgtgtcg
     3661 ttgaacggca gaccgatata atcaaacggc tcatccgcca tggcagccac cgcgccggtg
     3721 agaaccggag cgcccgttcc ggcggtcccc gtcgccacgg caatctgtac gcccgctggc
     3781 agcacttcac ccccaccgaa gccgtagtaa ttgaggctga caggaacttc attcccgcaa
     3841 agccccttat gacgcgcggt cagcgtgaca acaccagccg aagatgaagc tgtaaacggc
     3901 agagtcggaa cggcattgat ggcatcctgg atactgctgg caatcgtcgt gacgttatcg
     3961 ccgttggtca ccggagcctg cacgcgggta cgtcccacat agacattcac cgtgccgctt
     4021 tcggttgctt ccccggtcac cgtcagcgta accgttgccg ccgcgcctgt ggattcagga
     4081 acggcaatca catacagctc gccaaacggg tcagtctggc gataagcctc gaccatacgc
     4141 gccagctgac ttcccgcacc acaaatctgg cgtgcatagt ctgccgacgg catcagtacc
     4201 agactgttgg caacaatctc tgcaccgtta ttggcatgac caatcagcag cgatgctccg
     4261 ctgtcctgtg cagtattcgc cgcctggtta tccatttccg cataaaacaa cggaaccagc
     4321 gtattcgacg gaatggtgtt aaagcttatc gtcatcggtg ttcacctttt tattcacgcg
     4381 ccggatatca cccgctgctt cacggcgcag ccagtagttg ttctcgtcaa catttcgccc
     4441 ttcggcgggc aaaaggtcgc cgcgggcagg gtcaggcact gaccgccctt taacaggttt
     4501 gacaaacatg aggatcctca ggaaggaagg gttatttcgg tgtgatgttc gatatcgccg
     4561 tcaggcccgt taccgggatc gagataatca acatcaatcg ccagcgttcg cagttcatcc
     4621 agactgttca gctcatcctg ctggcgggta tcgtcttcgg tcagctcgct gatgaccgaa
     4681 aaatcgaact gataaatcag ctcatgacga ttcagatcca gcagcgtgcc gccgtcatag
     4741 gtaatcgggt taccgcacgc ttccgggttc cagcccagca gggccttaaa gagcatctgc
     4801 cggacatcgt ccaccacatc atacgaagca aactgaccgc gctcatcacg cccgttactc
     4861 agtatgacaa ccacggagaa gccctctttc agctcctgcc agtagtcggt ctggcttttg
     4921 ttttctcccg gagaatcatc ccccggtacc acatacgccg ccgggagtct cagctttccg
     4981 acctccggca gatttttgaa ctgtgccgcg cctgccaccc ggttttcaaa atacgggcag
     5041 cgggcacgca gcgcagcaat aacaggcgtc agtttcatct gtgtcgtcgc tccggcttca
     5101 gtgatttacg caattcccgc gccagaaaat agcgtgtcca gctgtggttc ttttcaagcg
     5161 tttccaccat gaagttatta cgtggagcca gtcgccagcc gctgccaccg gatgcaccac
     5221 gatgatggct gcgacgacgc tttgcacctc gcctcacgcc atagaacaaa aaagccggat
     5281 aaaaatcacc ggtgatacgg cggtttccct ctccattacg ctggttaggg gctatacgtg
     5341 ccataaaacc agggcgatgt ttactggctc tgggtaccat gtaaccaatc gaacgagcca
     5401 ggcgtccggt ctgataaccg gggttttcac ccggtgccga ccgcgcacgg cgcatcacca
     5461 gccgacgggc atcacgcata tgacgctgac caatcgtgac aaacgcccgc cggacacggg
     5521 cgcggttaaa gcgcatctcc gcgggctgct gaaaatcaac gtgcaaaaag gaagtcgtca
     5581 ttgttgcctc cgtgactctg cctacattcg cccagctccg tacactccag cagcagaaag
     5641 cgccgcgccc cgttcagatc gcgctgacgt ttcacccggt acacactgtc accccagacc
     5701 acctcataat cagcggtgat cccccggcgg taacgaatgg tgatgtaatg ggtgatggcg
     5761 tcaccggtct gcgcggtttc ctgccaggtg gtggcactgg tctggacaac cttcgcccat
     5821 gtccggaacg caaccgggta ttgaggctcc acgccaaagt tatccgcggg catatccacc
     5881 cgctggcgga tcaggacgcg tttattcagt tcaccggggt ccggcagaat gtaggttgcg
     5941 ctggtctgcg cctgacgaat tttcattgcg gaaagtacct gtacgggccg acaagccagc
     6001 caaaactctg cggcatgtcg agtttctcca cttccgtaac cgacgagcgg ttttcgtaaa
     6061 aatggctgat aagcatcagc atccccagac gaatatcatc cggcaggtgc agcccgtccg
     6121 gatcgctgtc cggaatggtt tcatccggtg catagagctt ccggttcaga tacgtttccg
     6181 tccgcttttg cgccgcacag gccagcagtt gcagatggcg gtcatcagca tcgaaatcct
     6241 catccagccg gagttgggct ttaatctctt ccattgtcag aagcatactc agccctcttt
     6301 actggtcgtg gcttttttct cttttgccgc tttactgctt tttgcactga ttccgcgctc
     6361 tgctaacccg gcctgaagtg caatctcctg cacccgggca ggaagcgccc cgtcgtcata
     6421 ctcaccggcc cgaatgacct caacacgcat accgtccggt gaccatttca gatcttgttt
     6481 caggatcatg attcttcacc cgtcagaaca gggggtgcgg ttccgcgccc cagagtgatt
     6541 acgccgctgc aatcttcagc agtttgatgg cctgcgaatc gaccagcatc ccgccggtgc
     6601 gcttggtggt ataaaaaccg acaaacggtt tattggtgta cgggtcacgc agaatgcggg
     6661 tgccgatacg gtcaacgatg gtgtaacccc gtttgaagtt accaaatgca atggctttcg
     6721 catcagcggc gatatccggc atctgttcgt tttcagcgat accgtaaccc gccagagagg
     6781 acggctgccc cagttccagc cccggacgcc acagatagtt accctcgctg tctttaagca
     6841 gacggatggc aaacaggctg ttgttgttca tcatgaactt cgcgccagtg cggtgtgcct
     6901 tacgcagcgt gtaaatcagt ttgataatgg cgtctgcggt caccgccgtc gcttcgccgg
     6961 atacaatatg ctgaagcttg ccgaacgccc ggaccttatc ggtttcatca gtggattcat
     7021 acgccaggaa ccctttcggc ttcttggtac catcgccggt ggtaaaggca atttcttcct
     7081 gttcggcaaa ttcggttgcc agctcgctgt tgatccatgc ttccacgttg aaaaaggcat
     7141 catccagcat tttctgggtg gcctgcgggt taccgtagat ttcccccatg aaaggttcaa
     7201 tcagtcccag ttttgaggtg gcggtctggg agcgcgcgtc agtctcgcca acccatccgg
     7261 aagccgtgcc gcccagattc accagttttt tgtagtcgga accgccaaca gtgattaccg
     7321 tggcttcctg gcgcatcacc acttcatctt tcagcagggt gagaatgttg cgatccagtg
     7381 cttccggcac ggcatagcca ccgtcttcat cggtgcccac ctgcaatgcc ttgcgctcca
     7441 gatcgcgcag accgtcttca cggcctttac gcaggaagcc cacaaacgcc tctttgtgct
     7501 ctgtggccag tttattttgc gcaccacctg ccggacgttt cagctcaagc agctcttttt
     7561 caaggtcgct tttgagattt tccagctcgc tgagtttccc gttcagggtt tccacctgtc
     7621 cggcaagttt gcctttttcc tgctcaatcg catccacgcg cttgtcgttc tttgccttga
     7681 agtcgtcaaa cttctgctgc agctcctgcg cgacctgttc gacatcttta atatcaaccg
     7741 ccatcgtatt tctcctgatt agaagttcag atttttcagt gcattcagtg cagagcccac
     7801 atcctcagcg tcgcgcaggg acagtgcgcc atagcccccg gccatgaatg ctttggcctg
     7861 ggtacgggag agtccgacat cacgcaggac tctttcgatt tttttctgtt cggggatttc
     7921 cccgcgggcc agtgcgttct tgacgtcgct gatccgcgcc tcgtcgttag acgggaacgt
     7981 caccagactg acttcccaga ggtcgatttc tttcagcaga aaggcttctt tgctccggtc
     8041 gtattcccag tctttcagga cgtacccaat agaaaggccg gttaacgaac cggccttcat
     8101 gtgtgcatgt gcgcgttttg cgaggggatc atcatcaatg agcaaccgcc ccctgacgta
     8161 aagcccgaca tcgtcttcct tcatttcggt gtaaacaccg atgggctcat ccatgcggtg
     8221 ctgccagagc agcgcaggta acgcttttct gtcactccac gcccgcaggg aagcggcaaa
     8281 tgcccctgac atcaccacat catcgtggct gtcctttaca ccaaagacgg agccataccc
     8341 ttcaaactca ccggagtcac tgacagattt cagactcagc ggtacatcaa gacgttgttt
     8401 cgtctgcatt ggcgttatcc ttctgcttac cggctttact gccatcggag ggtttcgtgg
     8461 tcatgttcat cggtgtgaga tagacatcac caccgggacg cggattcata tcttccaggt
     8521 cgcggcagtc attgggagag taaattcccc agttgatccc agtggcgtag gcttcaaaac
     8581 gggacttcat atccccgcgc agtaaggccc cggcgttaaa tttggcgtaa taaacgccct
     8641 gcttactttt tcgtaccagt ccggtgttga tccgctgctc aatgcgggtc agatacggca
     8701 ccagtgaata gttgataaat cccagcccca gctcttcgat attgttgaag gtggcgcgat
     8761 cggtgttctg caccatgtgc aatggcaccc ggaacagacg acagatttct tcaagctgaa
     8821 acttgcgggt ttccaggaac tggctgtcct cggcgttcag cgccatcgac ttccagtcca
     8881 gccccatctc aaggatcatc gggcggtgag cattgccaag cccggtgtga cgctcctcaa
     8941 aatctttctt caggcgctcg taagcctgat ctgacagcgt ctgctctgta cgcaacacac
     9001 ccgacgtcac cgcaccattg ctgaacagtc tggccccgtg ctcttcggtc gctgccgcca
     9061 gcgatattgc ctcgcgggca taggcaatgg gattcagccc caccagtccg tccagcgtca
     9121 gcgtgcgcac atgccagata tcctcctggc tcagtacatc cgtggagcca tccgggaatg
     9181 tgacctgata gaccggctcc cagctactgt taagcttcgg taccacacag ccgggatcga
     9241 cgggcagcag ttcagccact tcgccaaatg ctttcacttt gtaggcgtaa aagtttcccc
     9301 gcaggcacag acaggtgacc accagctccc aaaactcctg cggcgtcata tagccattgg
     9361 gatgcgtgga aatcagctta tgcagacgtt cgccggtggc tctctgtttc aggttgccgt
     9421 tcaggtgata caggttgcag ggcaacatcc cgaccgactc tgccagcacc ctgacgcagg
     9481 aaaaaaccgc cgtcagtcgc atggcccgct gactgctgat ctgctttccg gtataggtgt
     9541 cgtaggacag cccgatagcg tccgccagct ctgctggcgt ggtcaccggt gcgtcacttt
     9601 ttcgttgaaa taatcccgaa aagaacacta tttacctccg cagactgacg actgtgtacg
     9661 gtcgagatat cgcgccacca gccacgacca gaacaggcac aacgccccgg caacaacaaa
     9721 ccccgccggg ggataaatca gccaggcacc atacgccagc aaaagcgccc ccagcacgcc
     9781 caccagaggc gcgagaatca gcatgatcat aattacctca gttaaagcga gcggatccca
     9841 taggactcaa tgtggtcaga cagcgtgtct tctttctcgt acagcatggc tctgccaacc
     9901 gccataatca gcgcaactgc accatcgatt ttgttttccg cctgctcttt gacgggcttc
     9961 accacatcat cgttacccgg aatggttttg ccgaccacgt tgccgataca ccaggtcatg
    10021 atgggattgc catcatgatg aaagcgcccc gattcaattg ccgcttccag ctctttcatc
    10081 gggtcggaca tgttggtgta gttctgaatg atagtgatgg ggttcaggtc ttcatcagca
    10141 aggtcatgtg acaacccggt cgccccgaag gggtcaatgg gtgactcact gaccgggctg
    10201 attttgttcg ccgctttggc ctcctcgagg atgtagcgat aatccacctc cgcaccatcg
    10261 gtaacggtca gaacgcccat ttccacccat ttctgaaagc gttcggctgt ccgtcgatct
    10321 tcatttttct cgacgctgta caccgtgtca tacggtaccc agaaacgcgg ggccacactg
    10381 tagtaatgcg ttttaccgtc aatctcgcgg gtataaagtc gcgccatgct gttcatatcc
    10441 agcttacgcg ccaggtcaaa ggccagaatg cacggctgcc cctcgaactg ctcaagggtc
    10501 agtgatttat cctcgcagct ctgccagctc accaggttga aatacgccga acgcgccgac
    10561 acccagatat tgaggtgttt tgttttaaag acgtttgcca gacgggcgtt atttttcgca
    10621 cgctgctgct gacttaacaa aaattcgcga taaaccgaca cgccaatatt cgggttagct
    10681 ttttccagca cctgcgggtc ggtccagtcg tcaccttcat caacggtata gatgatcccg
    10741 aacagttcat cgttaggcac cgagccgttg agcatctcga tgacttcccg ccgtttgtcg
    10801 tagcacggcc cctcaatgtt gtacccggcg gttgtgatag cccacatcag tggctgacgt
    10861 cgcgccccca tcccggtaag catcgtggtg taaagcgcat cggtggcgtg ctcgtgatat
    10921 tcatccacca ccgcacagtg gggtgatgaa ccatcaccgg ggttaccgat cagcggttca
    10981 aaacgcgcac catcctccgg acggttcatg tttgaggcgt taacctcaat cccgaacgct
    11041 tccgtcagca tgggtgtgcg tttacacatc agtcttgccg gacgaaagac ttcccatgcc
    11101 tgtttctccg tcgtggcacc ggaatacact tccgcgccga actcgttatc acaggcaaaa
    11161 caatacaggg cgacaccggc agaaattgcc gatttgccgt tcttacgggg gatttcggta
    11221 tacacctcac ggaagcggcg cagccgggag cctttattga cccagccaaa cgcgcagcag
    11281 atcacaaaga gctgccacgg ctccagcgtg ataggcatcc tcttgaatgc ccactcaccc
    11341 ttggtgtgcg gcaacagctg aataaatttg gcggcccgtt cagccaggtc cttgtcgaag
    11401 cggtaacgaa acgacttact tttttccgcc atcaggtcat caagatggcg ctggcaggcc
    11461 tgaatcacaa actggcaggc cacaatcttt ccgcgcacga catcacgggc atactgattt
    11521 gcagcattta cgttggggta agatttccgg ctcatgattc gataattttc agaaacgggt
    11581 tagtggcttt cttctgcccc gccaggccaa tcagacgctg gcggctgctg gggtcgagtc
    11641 cgagcattgc ccccgtactg ctcatctcgg actcctgttc ttttttggcg gtcagctccg
    11701 gatttttgac catgccgccc attgcaccgg tgatggtgtt gccctgtctg gcaatatttt
    11761 tcacggcacg tcgccagaac tcataggcca cgcaccaccg ctcaagcacc gcgaggtcag
    11821 tcacgcacag caggccctga ccgcagagtt ctttggttgt cagttgccac atgatcgtgg
    11881 cgagagggag atcttcttca gcgaaccact ccggtggctc aacacctttg atgggcgtaa
    11941 aaacaggttc atctttgttc agggctcgct tgccggggtt tccggccagc gccttgcgcg
    12001 ccgttggctt ggggcgacgc ccggaacgcc ccgccgttcc agccatatgc ggcactcctg
    12061 gttaaatttc atttttcgcg ggtataaaaa aacgatgggg cgggcagtcc ggaagacgtc
    12121 aggccgcagg gatttgaccc gcccctcccc tcaggcagtt gagaattatt atcacttcaa
    12181 ccgttcacgg gccgtcttcg ccttatgaca cggccagcac aggctctgca gattactgtc
    12241 ggcatcagag ccgccatgcg ctttagggat gatgtgatca acggttttcg cttcacgcac
    12301 cacaccggca cgcaggcaca actggcacag tcctttgtca cgcttcaaca cacgcacgcg
    12361 gataacaccc cacttcgaac cataaccgcg ctgatgacgg gattgtcctg gcttgtattg
    12421 cttccagcct tcgcttttgt ggctttcaca atagcctgac gggtctgtgg tggtatggcg
    12481 gcagccacga acacggcagg cttttgggat tcgtgatggc atatgtactc caatgaagaa
    12541 gccaccgaca tagcctcctc cattcatcgt gaaactattt tcatctaccc agtaatgaat
    12601 tctttgtaga gttgtgatca atacaactca ctaatggaga ggcttgtcca acacgttgga
    12661 caagtttcct gtttgattta ctggacacta tagaaggaca gaatgccttc atcactcgaa
    12721 taacatcaat taaggaggtt caacatgttt cattccacaa atcatcaggc tgtaattatg
    12781 gctgcatcag cttgtaccac agaccttttc cgcttcactt tgagcctgat tcatttctac
    12841 ctgaccggct cgcctctatc tttttaatcc ccgctttatc caaattgcat tgccagaatg
    12901 ccgacaacag actgacattc aaatcctgac tacctccaat agtctgaccg tacacctata
    12961 tagttttaat tttcatcaat ccatttaact atcgtttaat tgttgtcaca taggattctg
    13021 ccgtttttaa caatgcagga taataagatg aaaaaaatgt tgttttctgc cgctctggca
    13081 atgcttatta caggatgtgc tcaacagacg tttactgttg gaaacaaacc gacagcagta
    13141 acaccaaagg aaaccatcac ccatcatttc ttcgtttcgg gaattggaca ggagaaaact
    13201 gttgatgcag ccaaaatttg tggcggcgca gaaaatgtgg ttaaaacaga aacccagcaa
    13261 acattcgtaa atggattgct cggttttatt actttaggca tttatactcc gctggaagcg
    13321 cgggtgtatt gctcacaata attgcatgag ttgcccatcg atatgggcag cgctatctgc
    13381 actgctcatt aatatacttc tgggttcctt ccagttgttt ttgcatagtg atcagcctct
    13441 ctctgagggt gaaataatcc cgttcagcgg tgtctgccag tcggggggag gctgcattat
    13501 ccacgccgga ggcggtggtg gcttcacgca ctgactgaca gactgctttg atgtgcaacc
    13561 gacgacgacc agcggcaaca tcatcacgca gagcatcatt ttcagctttc gcattagcta
    13621 actccttcgt gtatttttca tccagtgcag caacatcacg ctggcgcatc tgcatgtcag
    13681 taattgccgc gttcgccagc ttcagttctc tggcattttt gtcgcgctgg gctttgtagg
    13741 taatggcgtt atcacggtaa tgattaacag cccatgacag gcagacgatg atgcagataa
    13801 ccagagcgga gataatcgcg gttactctgt tcattgctga ccccacaaac agatttcacg
    13861 ctcaatctca cgacgagtca tgagaccttt ccattgctta ccgccagcat atgtccagcg
    13921 acgtagctga tcacatgcgc ctttgatatc gccctggttt attttgcgaa gaagcgtcga
    13981 tgttctgaaa ttgccagcgc ccacgttgta aacgaacgag taaagagcgc cgcgcgttgt
    14041 ttccggtata tcaactttta tgtacgggtt aatttgtctg gcgaccgtgg caaggtcttt
    14101 attcaggagg gctttgcatt ctgctttggt atacgtttta ccgagcatga tgtcttttcc
    14161 tgtatgcccg tgacatacag tccatacacc aacaatatct ttgtatggta tgtagctgac
    14221 accttccaga ccatcgttac cacttgggcc agtgattaac actgatgcta tagcaattgc
    14281 tccgccacca atagcagcag caacggcttt tcgtaatgat ggaggcatta ttcacctctc
    14341 gcagccttgc gcttatcttc tttaatcttg aaataaaggt ttgtcaggta cgtcagcagg
    14401 ccaaatacca ggctacccag cacacctatt gctgcccact gtgagggcgt gactttatcg
    14461 agcagctgta aaaaccagta accggcacta cctgctgagg tgccataggc gacacccgtt
    14521 gttaacttat ccatggattt cataacccca cctcgcagac aaagcgggtg taaattgagg
    14581 gaatacaacg tatcgcaaaa aagcagaaac gtaacagact cggagtcagt gaataactca
    14641 ggtattgagt tatcagctaa tatcgagact caaaaaatgg aaaaaccagc tcgacggcgg
    14701 gtttaagctg tgtgacgaag taaccactct taacagcata accaattttt tacgtacgta
    14761 aaccactgaa tgatatttat gagaatgcta ccgagtgttc aaaacaccac cacaaataca
    14821 taagcaaatc tcaataaata accaacaaat aatttccagt gttattttta gccgatttaa
    14881 attgaacctt caaattatag agcacttata aataacagcc gttaatataa attggctaat
    14941 agatttattt ttattcagcc aagagctata aataggattc gatagaaaaa agttcagata
    15001 aaaatagaga tctacttcac aaatcaaacg agaaaccaaa acttacatct tgaaataatc
    15061 acattgatta gatgaatatt tatcgcgcag tgacatcatt ttttaataat agttcaaaaa
    15121 aaagggctca cgatgaaaaa attaacagtg gcaatttctg ctgtagctgc atcagtactg
    15181 atggcgatgt ctgctcaggc agctgaaatt tataataaag acagtaacaa gctggatctg
    15241 tacgggaaag ttaatgctaa gcactacttc tcctctaatg atgcagatga tggtgatact
    15301 acttatgccc gtcttggctt caaaggtgaa acccaaatca acgatcagct gactggtttc
    15361 ggtcagtggg aatatgaatt caaaggcaac cgcgctgaat ctcaaggttc ctccaaagac
    15421 aaaacccgtc ttgcatttgc aggcctgaaa ttcggtgact acggctcaat cgattacggc
    15481 cgtaactacg gtgtagcata cgacatcggt gcgtggactg acgttctgcc agaattcggt
    15541 ggcgatacct ggacccaaac agatgtgttc atgactggtc gtaccactgg tgttgcaacc
    15601 tatcgtaaca acgacttctt tggtctggtt gatggtctga actttgctgc tcagtaccaa
    15661 ggcaaaaacg atcgtagcga tttcgataac tacactgaag gtaacggtga tggcttcggt
    15721 ttctctgcta cctatgaata cgaaggattc ggtatcggtg caacttatgc gaaatctgat
    15781 cgtaccgaca ctcaagttaa tgcagggaaa gttcttcctg aagtatttgc ttccggtaaa
    15841 aatgcagaag tttgggccgc aggtctgaaa tatgacgcta acaacattta cctggccact
    15901 acctattctg aaacccagaa tatgactgta tttgctgatc acttcgttgc taataaagct
    15961 caaaacttcg aagctgttgc acaatatcag ttcgatttcg gtctgcgtcc gtccgttgct
    16021 tacctgcaat ctaaaggtaa ggatcttgga gtatggggcg atcaggactt agtcaaatat
    16081 gttgatgtag gtgcaaccta ttacttcaac aaaaatatgt ctactttcgt tgattacaaa
    16141 atcaacctgc ttgacaaaaa tgacttcact aaagcactcg gtgtaagcac tgatgacatc
    16201 gttgctgtag gtctggttta ccagttctaa tctgattacg aaaaagatat gttgcgggag
    16261 gctttgcctc cccaacatat aagtggctcc ctcaagccac ttcctttagg agcacaacct
    16321 tgcttctaac tatataaacc ttctgttata tattaccctt tatttttggg ggcgttgcaa
    16381 cgccccattt ttaataactt ttagtaaaca actggcatat taattagagt tattaacaac
    16441 gatatccatc tctaaccgga tatctaatgc cattaacatc ccttcaatta taccctcagc
    16501 cttctgtaac cttttcccga tataaccatc agagcagcaa tgcttacctg ccagtgacat
    16561 gaatgtcata ccgactacat aataatctac taataaatcg tgcaaatcgc tgttgttctt
    16621 tttcagacgg gccatgcacc cgcaaatgat catcgcgtca tcgtcacaac attgcgggcg
    16681 agattttact tttgaagtaa ttaatccctt aaaaccggcg gcaatggacg accaggtcac
    16741 atcttcatga ttattagccg cccacgctcc ccaacgctca agaaccatct gaatatcacg
    16801 catcaactta ctccacaaaa atcagaccag aacgccaatt acaagcaaaa atcaacaaaa
    16861 tagtattagt tgattgttat ctctgacttc atactcctgc tcctgtcagg gttttggcgt
    16921 aattcttcag tatccggtaa tcggtcaaaa cagaaccagg aaaacgatat aagcgcaggc
    16981 gcacccagcg gcggcgaaga cgctctgcca tataagactc aaacatcatt cattccccat
    17041 ttcggtgatg gtcagttcca gcctcccacc tttggtaaca ggcatcttca caacgcggta
    17101 atcaacgacc tgagcatcat ccagccagaa acctgctttg gtgagtgcgt caaaagcggc
    17161 cttttgcaga ttatccaggt cacggcgacg gcgatccggc atgtggcact caatacggat
    17221 tttcactggc atagccaggc cgatatccag cattgcgttt ttaatgattc gggtgacgtt
    17281 atcgcggtat gcctgccctt ctgcgctgat gtgtgtgcgc ccgcgattat ggcggtaata
    17341 gcggttattg ctcggaggcc agggtagtgt gatgtggtaa gtattcacgc cttgattacc
    17401 ccctctttca gccagataac ctgcgttctc gccatacctt ccagcgcgca ttcttttgcg
    17461 tactcagcat cgacaaaatg cgtgcggcgg tcgatttcgt cgtgacaggc agaacaggca
    17521 atggtggcaa taaggtctgg cggtttaata ccggtgccgc acaatccagc cagccggata
    17581 tgtgccagta cagacgtttc agggttgcca ttacatacgc cagtgattct tacctggcat
    17641 tcccgaccac gcgctgcttt tctcaaatca gccatgattc ctccttgctg ccagtcgcaa
    17701 ccatttttta tcaaccaggc tagcggtata tccgagcagt gttggtattt cggatggctt
    17761 cagctcaggc ttacgcttac gacgatttgg tactctgtag atgtgtccgt tcatgacacg
    17821 aataagcggt gtagccatta cgcctcctgc ttgtcgcgca gcagctggaa ctcgcagctc
    17881 tgcggaatag tcaggtggca gccaatattc atcgcccagg cttcaacctt acacaggaag
    17941 acatacatct ctccggtatc aagatcggaa gtatggcgta acgactggat agtagtgatt
    18001 tcgccggtta cgacatcaac caggtccttg gtttcataac cgaggtatgt gtgtttgaga
    18061 gcatctttta cccatgctgc ggtagcgaac gatttccccc tgctgatgag gtattcactg
    18121 atttcgctgt accacatgtg gctgagtgca ttctgggaaa gactgcgttt ctcacgccac
    18181 ggtttaagca ccatgcgaaa gcattttccg tcctccagat aaggctggat ctgctggccg
    18241 atagcggtga agttaccgcg atgcagtttg atgccatctt gtggtaggtt cacgcttcac
    18301 ctccgcagag gtcagacgct ggatgcaaaa aatcgcaggt gcatttctgc atctgtgaag
    18361 ggagaagaga gtttggattg tatgtgcgca taaacgtccc cgtttagcgc agaagtcacc
    18421 ggagttgttc aagctccgat gactttatta ttacgaattg attttacaaa atcaaaaggt
    18481 atgttagtga cgcgggtctg ttattatgcg agaagggttt ccgtataaaa caaggacctt
    18541 acttccttga gtaaataacg gatctttgcc ttgaacaatg gtcattaaat tcccattctc
    18601 agtttcgaca acatattcca tgcctgtttg ttttgttgct gaagattcga ttgctgcccc
    18661 ggcaatacca ccaatgactg caccaccaac ggcaccaacg atattagaac gaactccccc
    18721 accaagcgca gaaccagcgg ttgcccccac ggcagcccca gcagtcccgc ctaacgcgga
    18781 agtcccactg atatcaaccc ccctagcact aataactgta ccagcgatag ttcgattaac
    18841 catgcccaca gagccaacag aataactatt tggcgatata ttttgtgcgc atccaaccaa
    18901 cactaagagt ggagcaatta cgaataatcg cttcatttag ctaccctaac aggaaacatt
    18961 ggacgagaaa gatcaacact ttctaatgct tgcaagaact gcgttatgtt gttttgcacc
    19021 gcgcgattaa cagattcgcg tgctcgaaca ataccgtaga atgcgtaact ggctggaaca
    19081 gtaccggtag actcaatatc ctgcgtatat ataatatcac cattcgcacg gttgattatt
    19141 tcataccttg caattgcttt agttgtcatt gaaacaccaa aagcaggaac gtcaagagcc
    19201 aacactttaa catttaagct aaccgtattt ggtgaactat cacgaaaaat agtcattcgg
    19261 tcgagtgctt cctgcaaaga ttcacgccaa attggagtta tagcctccat accagcagtg
    19321 atatcccctt tctgctcatc tggacgagca agtgataccg ttaatgactt aatttcagca
    19381 tctatttttt tctggctaac tcccacgtta ggtgttgaaa aattcaatgg tggcacacta
    19441 gcgcaacctg ttaaagaacc aataatcatg gctaataata ttatcttctt cataaattta
    19501 ccttattgtt ataaccaaag gaattataaa gtaaaaaagt tcattatcac tagccattaa
    19561 cgacatcaat ttcagagaaa catggtactc atttccacaa atttgacaca agtcattttc
    19621 acctacatat tccatcatac ttgatgcata tgttattgaa gcctctatcc tatccgttca
    19681 taatagcaat agttacccgg gtgatagtac ctctatgatt actcgtcttt ctgattgatt
    19741 ggattaaata tgcgcgccaa aatttatcaa ctttcgttat ggatatttat ttcgtttcta
    19801 gcgatctatg cctttattat ctataaaggt tcttatattg gagtagcatt gcatcaaatt
    19861 gcttggctca tcattattgc ctctggcttg attgctaggc taactaaacc aaagaaaaaa
    19921 tcaatttcgt ccaataatta gacatgtatt aaaaaaatga tatttttatg tacatagtct
    19981 attgaaaatt gccgcgataa aatgccaaca cccgcttcat cgcggcactc tggcgacact
    20041 ccttgaaaat cagattcgtg ctcacctttc cttcccgttc ttccttggta gcgaaccggt
    20101 aatacaccgt tcgccagacc ttaccatcaa taactaagat tcctgtccgc gccattttag
    20161 ccgcagcctg atttatgctg gttactgttg cgcctgttac cgcagcaacg tcctgcgcac
    20221 agaagctctt atgcgtcccc aggtaatgaa taattgcttc ttttcccgtc atacactggc
    20281 tcctttcagt ccgaacttag ctttgatttc tgcaatcttc gtcagagcct gtgcacgatt
    20341 tagaggtcta ccgcccatga caggaagttg ttttactggt tcaggtatag cctcaccacg
    20401 gttaattctc gcagtcatat gggcaagttc atcggcagcc ttgcgccgta attccgagtc
    20461 agtcaacgca ttggcccgca tgttctgata caggttggta accagccagt agtgcgcgtt
    20521 tgatttccac ggataagact ctgcatccgg atacagcccg cgcttccggc aatactcgta
    20581 aaccatatca accagctcgc tggcgtttgg cagcccggcg gtaacggatg cttcttcccg
    20641 gcaccaggcg acaaactgcc cgggtgatgg caggaatggt cgattctgcc gacgggctac
    20701 gcgcattcca gcgttaacct gttccattgt ggtgatcccg ttttcccgga aagccagaac
    20761 ccactggcgg cgaatttcgt tcagttcgtt ctggtcacgg ttagccaggc tcgcagggaa
    20821 agttgccagc aactggctga atacaccgtt gatgatctgc gctacctgct gtacctgcgg
    20881 cttttcgtcg tactgttccg gcatgttgtt ggcgatccga cgcatctgct cacggtcaaa
    20941 gttaatcatc tgtgcggcga tgtttttcat aaatccaccc cgtaaatcca gtcagtgttc
    21001 gtcaggtcga gttttggttt gccggctgtc acgccagcct gttgcttgtt tcggttgatt
    21061 tcgagctggg tccacttgtc gcggagtttg gccggactca gcacgttacc ggaccagaag
    21121 ttgtcctggc atgcccagcg gaacagcacg cacatgtcgc ggtggttacg tccgtcacgt
    21181 tcacgcatca ggcggatatc gttagcccac cctgcaaaat tcggttttct ggctgagggc
    21241 gcgatggtct tcaccatgtc aaacatccac tctgcggcgg tcaggtcttc tgctgtcccc
    21301 cacttgctgc cgctctgaat tgcagcatct ggtttcacca caggaagatc gttttctggt
    21361 tggtcagagg attcgccaga attctcggac gaaaaaggtt ttatattgtc ttttgttagt
    21421 ttgtcttttg tgtttacctg attcgggtaa acgcctttac ctgatttggg taaacttttc
    21481 ttacctgatt caggtaaatt tacctctttc aggtaaactt tatttttctt acctgattcg
    21541 ggtaatgttg cccattcact gaccacatta ttaataccga tattccgccc gctctgaatc
    21601 aaaatcccac gctttaccag aacacttttt gcagcagaac acttgtgcgg caatatcccg
    21661 gtcaattcgg acagttgctc gttgctcacc caatccagtt ttttattaaa gccatatgtt
    21721 ttgcgcatga cagccaggaa gaccagaagc tggtgctgtg ttaatccggc cagcatcaca
    21781 gcttccagca actcatttgc aatgcgcgta taaccatcat cgagatctgc cacgcgcggc
    21841 tccttttgtg ccgcatccgg cactggaaaa ttgaatatct cagcagtgtt tgccataatt
    21901 cctcccgcaa tgagtgtgtt acgatttgca cctgaaagtc ggttctgttc ccgcagaccg
    21961 actttcgcca tttctgaacc tgtcatattg cccccagcat ggtggtcacc atcgccatta
    22021 atggaccagc caaatccggg tccacacgaa acatcgacac aatgccttca ctcatctcct
    22081 tcagtttctg gtggcgtggt gcgttgagaa tgacagcctg ttttgcctca ctgagttcct
    22141 tttccatttc agccagccga gccatgaagc tatcctgctc aaccaggtgg ccgcgatatt
    22201 tcagcggtag tactgccaga attgctggag tcagttcacg cacgttattt cggtattttt
    22261 cagaatcgaa tttgttatcg agaaagcgga acagcttctg gcgtgcacga ctgacatcat
    22321 caggaaaatc gatagtgccg ccgccctgtg ctcgatactc attcacaatg agtgcggcaa
    22381 cgacatcctg attatctaca gccgaccagg cgcggatggc atcacggatt ttttcgtggc
    22441 ctggcacctg ttttatttga gaacgattta tcaccgcagt cgggataaat ccgctagtct
    22501 gttggtatgt aagtggttgc atagtcattg ccttatcagt taacgccgca gtttaggcgg
    22561 cagaattact cgcgttaaac aatggtgcga ggtcgggacg aatatctgct ggtttaatct
    22621 ttccaccagt ggctgagaca attttcatta catagcgggc atcaattccg ccaccgtgta
    22681 gccaacgcca aacagtgggt tgggctacac cgcatagatc tgccagtcgt ttttgactac
    22741 ctgtaatact gattgcgagt tgaatggttt gatttgtcat tatcaattcc tattggtatt
    22801 gcaatgaatg aataatagca atgcgtatta atccaagcaa tagcaaaacg tgttttgacc
    22861 atcaatacgc aagcgtataa attaaaactt atgaaaaaag aaactcttgc tgatcgctta
    22921 aacctagcga tggaacaatc tggaatgtct caaggcgctc ttgcaaaggc gtctggcgta
    22981 gctcaaccca caatctggag actgacaagc ggcaacgcgc gcggctcaac aaaaattgtt
    23041 gaaatagcta atgcattggg tgttcgaaca gaatggctct catcaggcat aggcccgatg
    23101 agaaatgacg gtcaacaatc agggaagcct gctgtcagcc attccaaata cttcaaaatt
    23161 gacgttcttg atatagaagt cagtgccggg ccgggtgtaa tcaaccgtga gtttgtagaa
    23221 gttctacgct cggttgagta ctcgtttgac gatgctcgtc acatgttcga tggcaggaag
    23281 gcggaaaata tccgcatcat taacgtgcgt ggtgacagca tgtcaggaac gatcgaacca
    23341 ggtgatctgc tgttcgttga tatcacggtt aaatctttcg acggtgatgg tatctatgcg
    23401 tttctgtacg acgacacagc ccatgtaaag cgcctgcaaa tgatgaaaga taagctactg
    23461 gttatctctg ataacaagag ctactcaccg tgggacccga tcgagaaaga cgagatgaac
    23521 cgggtgttca tcttcggtaa ggttattggg agcatgccgc agacgtacag gaagcatggt
    23581 taataattag cctgtagctt tttaaggcac actcttttca agaatattaa atagaacgct
    23641 atatggcata aacaaggact taggatggaa aagcctagct tcccacctct tcttacagca
    23701 ggatttcatg atatggatag tgatggcatc aagtctcttt gtgtcgacac cttcccaaaa
    23761 tccgttagaa gaagtatgct atactgtaat tttatacagc ttattgagca atttaaactt
    23821 gttaatcagc agtgtctatg tttctctgaa gtgtggatcg atggttcatt cactacagag
    23881 aaacctgaac ctgatgacat agatatactc gtggtcgtcg attatttggc cctaaactct
    23941 ttgccaaaca cgctgatgcc attggttagc tcattgttaa atagagattt tattaaagaa
    24001 aactacagca ttgacgttct tttgctgcct gaaaatcatc cagaaatcga ttatagtgaa
    24061 aggcgaagtt actggagagg gtggtttggt tttgatcgga aggagaatcc taaaggcctc
    24121 gtgagggtaa tgttatgagc gaagaaaaaa cattcaactc cctcaaggag cgaattgcgt
    24181 tcattcaacg cgatgtggat ctgcttgctc aaaataaggg gagatcattt gctgatgaca
    24241 ttatatttag atcacttgac tcccatctga gcgatctccg agagagacaa cgtgcaatcg
    24301 ataaccaaca tcctttacgt gatttcatgg agttgagatt aaaaggtgtt ttggtcgatt
    24361 tcgggtctat tccgttagat attctatctg taatttcagg taatctcgca tcccttgtac
    24421 agaaagcagt ttaccgactt ggatctggga aagattctag tcgtgtgccg attgatgtta
    24481 aaaaatcatt agacatgaga ttggcagact tgcgtccagg ttcgacgaag ttaggtgtta
    24541 ctttttctac tggttcttgc gagctcatcg aaacagtatc cagtcatgct gttaaggaga
    24601 tttttgcact actctcatcc attgatgaag aaacattcac ggctaaaatt gccgaaattg
    24661 gttcgcaatc aacagctaac ctaaaaaaca tcataaatga gtgcgaaaaa tatagtctta
    24721 actttgatct tacttggatt ggacctttaa gtgatggtac cagacaagtg tcaatttctt
    24781 cagaagatat aaaaaaactg aatgctcgct tagctttaac gaaggtcatt cagctaccgg
    24841 atgagcatat atcaggcgaa cttgctattt tatccatgta cgggaaattg gagattgcaa
    24901 gcgagcttgg aaaaataaag gcttcttatc cgattgatat gttaggagaa attcaaagta
    24961 aatataaagt tggtgaacga atatcgctcg tagtaagcgt ttctgagatt cacaatgaaa
    25021 gattaggaac atcacgacgt aactacatgg ttaaaaaaat cgaatagtga tgctacccgg
    25081 ccaccgtgcc gggttttctt ttgcctcccc ctcatcacac aaaccgttcg aaaaaccacc
    25141 ataacccccg cttcagttat cgctatgcga tgcaagtcac aaaattaatt ctttttgcta
    25201 tcaaacattt aatatcaaaa cacatcaaac aatagcgata agtattgatg tcaccaatag
    25261 caatagctat tatcaccata tcgcaacaac acaacgatac ggcaaccacc tgattcaccg
    25321 ttgcgatgac cgcttagatc cgcagcttga atttcagcag gctccgggga gtgcgagggg
    25381 tgaagcggac gcgtgaacgt cggtgtgacc agctgaaatc aactcaacac ttcatacctc
    25441 agtcgcttca acgaggcgac ttagttatga caaccggcgg ccatccaccg cctgaatacg
    25501 cgcagaagtc tcaatatgtt cagcagccca gcttacgggc aggagttttt tatggttcat
    25561 caacattacg gaacgcagac cgttaatcga ggtgcggtca tgccaggaat gctggtcaaa
    25621 cacaaagatg gtacctggac tgcatcagct aatttacgcg gacggcttta tctgcatcgc
    25681 ggcatcgagc gcacttatac ccgtgatttg ctcgtagaag tttttctcga cggacgcggt
    25741 aacggcctga atcactaatc ccctttcctg ttttcctaat cagcctggca tttcgcgggc
    25801 gatattttca cagccatttt caggagttca gccatgaacg cttattacat tcaggatcgt
    25861 cttgaggctc agagctgggc gcgtcactac cagcagatcg cccgtgaaga gaaagaggca
    25921 gaactggcag acgacatgga aaaaggcctg ccccagcacc tgtttgaatc gctatgcatc
    25981 gatcatttgc aacgccacgg ggccagcaaa aaagccatta cccgtgcgtt tgatgacgat
    26041 gttgagtttc aggaacgcat ggcagaacac atccggtaca tggttgaaac tattgcccgc
    26101 caccaggttg atattgattc agaggtataa aacggatgag tacagcactc gcaacgctgg
    26161 cagggaagct ggctgaacgt gtcggcatgg attctgtcga cccacaggaa ctgatcacca
    26221 ctcttcgcca gacagcattt aaaggcgatg ccagcgatgc gcagttcatc gcattgctga
    26281 tcgtcgccaa ccaatacggc cttaatccgt ggacgaaaga aatttacgcc ttccctgata
    26341 agcagaacgg catcgttccg gtggtgggcg ttgatggctg gtcccgcatc atcaacgaaa
    26401 accagcagtt tgacggcatg gactttgaac aggacaacga atcctgcaca tgccggattt
    26461 accgcaaaga ccgcaatcat ccgatctgcg ttaccgagtg gatggatgaa tgccgccgcg
    26521 aaccattcaa aacccgcgaa ggcagagaaa tcaccggacc gtggcagtcg catcccaaac
    26581 ggatgttacg gcataaagcc atgattcagt gtgcccgtct ggccttcgga tttgcgggta
    26641 tctatgacaa ggatgaagcc gagcgcattg tcgaaaatac cgcatacact gcagaacgtc
    26701 agccggaacg cgacatcact ccggttaacg atgaaaccat gcaggagatt aacactctgc
    26761 tgatcgccct ggataaaaca tgggatgacg acttattgcc gctctgttcc cagatatttc
    26821 gccgcgacat tcgtgcatcg tcagaactga cacaggccga agcagtaaaa gctcttggat
    26881 tcctgaaaca gaaagccgca gagcagaagg tggcagcatg acaccggaca ttatcctgca
    26941 gcgtaccggg atcgatgtga gagctgtcga acagggggat gatgcatggc acaaattacg
    27001 actcggcgtc atcacggctt cagaagttca caatgtgata gcaaaacccc gctccggaaa
    27061 aaagtggcct gacatgaaaa tgtcctactt tcacaccctg ctggctgaga tttgcaccgg
    27121 tgtggctccg gaagttaatg ctaaggcgct ggcctgggga aaacagtacg agaacgacgc
    27181 cagagccctg tttgagttta cttccggcgt gaatgttact gaatccccga tcatctatcg
    27241 cgacgaaagt atgcgcaccg cctgctctcc cgatggttta tgcagtgacg gcaacggcct
    27301 tgaactgaaa tgcccgttta cctcccggga tttcatgaaa ttccggctcg gtggtttcga
    27361 ggcaataaaa tcggcttaca tggcccaggt gcagtacagc atgtgggtga cgcgaaaaga
    27421 tgcctggtac tttgccaact atgacccgcg gatgaagcgt gaaggactgc attatgtcgt
    27481 gattgagcgg aatgaaaagt acatggcgaa ttttgacgag atggtgccgg agttcatcga
    27541 aaaaatggac gtggcactgg ctgaaattgg ttttgtattt ggggagcaat ggcgatgaag
    27601 catcctcacg ataatatccg ggtaggcgcg atcactttcg tctactccgt tacaaagcga
    27661 ggctgggtat ttcccggcct ttctgttatc cgaaatccgc tgaaagccca gcggctggct
    27721 gaggagataa ataataaacg ggagagtgta tgattcattt tcacggtggt ccaataactc
    27781 ccgatacctg tgcgttgaaa gcctggaaag gcagacacgc attcatcagt tttgctaatc
    27841 cagctcagat tgatctggct tccgaagtca cccaatcatt tgctcttgat aatggtgcat
    27901 tcacattctg gacaaaaaac aaggccgtag actggaatga atattacaga tttgttgaac
    27961 gctggggtaa tcaccctcgt ttctcattcg cggttatccc ggatgttatc ggcggaacca
    28021 gtgaagagaa tgacgccctg attgcggcat ggcctcacgg taaatttatt ggtgctccgg
    28081 tgtggcacat gaacgaacca gatgagcgat ttattcgtct gtgccatgag tttccccgcg
    28141 tctgcatcgg ctcgatgggg gaatacgatg caaaacgacc gagagcgtgt cgggctaaac
    28201 tacgcgatct tatacgtcat gttgtagatc agtacggcta cccaatcacc aagattcatg
    28261 ggttacggat gttaaataaa gacattttta ctcatgtacc gctttcgtct gcagacagca
    28321 cgaacgtcgc aagaaatata ggcatcgaca aatcctgggt aggttcgcca tatgctcccg
    28381 caagtaaaga aacccgtacg caagttcttg tggaacgcat tgaatcattc aacagtgcca
    28441 gttcacttaa ttacaacgct gaacgggacg tctttacccc tcaactggca ttcgaagtgt
    28501 gaggccaata tgacaataga acataataac gcccttcgca gcattgcccg tcaggctaat
    28561 tatgaaatca aaaaagccag acagcagttt ccggataaaa acgtcaatga catttgccgt
    28621 agcgtactaa agaagcaccg cgaaacggta acgctgatgg gattcacacc gactcattta
    28681 agcctggcga tcggcatgtt aaacggcgtc tttaaggaac ggtgaacatg aaaagcaaaa
    28741 tcatcaggga gctacaggct ccttttttat tgttcgcatt catcctcaag cgtattaacc
    28801 aacaattcag ggattaattg aagatggcag acatcattga ttcagcatca gaaatcgaag
    28861 aattacagcg caatacagca ataaaaatgc gtcgtctgaa ctaccagact gtatccgcaa
    28921 ctcattgttg tgagtgtggc gatccgatag atgagcgaag acgcctggct gttcagggtt
    28981 gtcggacttg tgcaagttgc caggaggaga tcgaacttaa gaacaaacaa tggggactgt
    29041 gatggcctca aagcagcaaa tttcaacatc gtccaactga ggtgtaaaaa tgttcagaat
    29101 catttttcct aacacctggt acgtcgacca ccacggcact ccctgcaaaa tcctgcgttc
    29161 tacccacaac aaagttcact acatccgaaa aggcagaaca tgtatcgcca gcatgttccg
    29221 ctttaatcat gactttgaac ctgtgaataa agctgatgca gatcggatag cagtagagat
    29281 cgaaacggca gaacacatta agaagttacg tgacatgcgt tcaaaaagca gaggtaacca
    29341 tggaatcata cagcctcaca ctcgatgagg cctgtcagtt tcttaagata tccagaccaa
    29401 ccgccaccaa ctggatacga acaggccgcc tacaggcaac acgcaaagac cccactaaac
    29461 caaaatctcc ttacctcaca acgcgacaag cctgcattgc ggcgcttcag tctccgctgc
    29521 atactatcaa ggtgagcgcg ggtgatggca taacagagga aagaaaatgt cactcttccg
    29581 cagaagtgaa atatggtacg ccagtttcac attgccgaac ggtaaaagat ttaaacagtc
    29641 tcttggaaca aaggacaaaa ggcaggcgac agagctccat gacaagctaa aggctgaagc
    29701 atggcgggtc agcaaacttg gtgaaatacc tgatatgacg tttgaggaag cgtgtgtcag
    29761 gtggctcgaa gagaaagcac ataagaaatc actggacgat gacaaaagcc ggatcggatt
    29821 ctggcttcaa catttcgcag ggatgcaact aagagacatc actgaatcaa aaatttattc
    29881 agcaatgcag aaaatgacga accggcgtca tgaggaaaac tggaaactca gggcagaagc
    29941 atgcagaaaa aaagggaaac ctgttccaga atacacgcca aaaccagcgt ccgttgcaac
    30001 gaaggctacg catctttcat ttataaaggc cctactaaga gccgcagagc gtgaatggaa
    30061 aatgctggat aaggcaccaa ttattaaagt gcctcaacca aagaataaac ggatccgctg
    30121 gctggagccc catgaagcac aaaggctgat tgatgaatgt ccggagccat taaagtctgt
    30181 tgttgaattt gcactggcaa caggcttaag acgctcgaac atcatcaacc ttgaatggca
    30241 acaaatagat atgcagcgcc gggtggcatg gataaacccg gaagagagta aatcaaaccg
    30301 cgcaattggc gttgcgctga atgatactgc atgtcgcgta ttgaaaaaac aaatcgggaa
    30361 tcatcaccgt tgggtatttg tgtacaagga aagctgtacc aaaccagacg gaacgaaagc
    30421 gccaacagta aggaagatgc ggtatgacgc aaacacagcc tggaaagcgg cgctgagacg
    30481 ggctggtatt gatgatttca gatttcacga cttgagacac acctgggcaa gttggctggt
    30541 tcaagccgga gtcccgttgt cagtgttaca ggaaatggga ggctgggagt ctatcgaaat
    30601 ggttcgtcga tatgctcacc ttgcacctaa tcaccttacc gaacacgcac ggcaaataga
    30661 ctcgatcctg aacccatcgg tcccaaattt gtcccagtca aaaaataagg aaggtactaa
    30721 tgatgtgtaa cttattgatt ttaatggtgc cgataatagg agtcgaacct acgaccttcg
    30781 cattacgaat gcgctgctct accaactgag ctatatcggc cctgaaagga catgttcacg
    30841 aacgtgaatc acggtggaca aggttaaaac taaccgggcg atgcgtcaat ggccttgtga
    30901 atcaaatggc tacttttgca tcacccggtt ttatttacgc acgaatggtg taatcaccaa
    30961 tgccgatcca cttgtaagtg gtcagtgctt ccagccccat tgggccacgc gcgtggagtt
    31021 tttgtgtgct taccgccact tccgcaccca gaccaaactg gccgccgtcg gtaaaacgcg
    31081 tagaggcgtt aacgtaaaca gcggacgaat ccacttcgtt aacaaaacgc tgggcgttgc
    31141 gcatatcgcg ggtcaggatc gcatcggagt gttgtgtgcc gtgttcacga atatgggcga
    31201 tggcatcgtc aagatcgctg acgattttga cgttcaaatc taatgacaga aactcatcgt
    31261 catactcttc ggctttaaca gcaaccacct tcgcagggcc tgcctgcaac tgcgccagtg
    31321 cagctgcatc tgcgtgtaat gtcacgccgc tttccgccat ttgtttgctt aatgcgggca
    31381 ggaagctatc ggcgatgttt ttattcacca gcaacgtttc aaccgtatta catgtgctcg
    31441 gacgctgagt tttcgcgttg acgatcactt ttaatgcttc agcgatctct acactttcat
    31501 caacgtaaat atggcatacg cctataccac ctgtgatcac cgggattgtc gactgttcac
    31561 ggcacagttt atgcaaacca gcgccaccac gcgggatcag catgtcgatg tatttatcca
    31621 tacgcagcat ttcactgacc agcgcacggt caggattatc aatcgcctgc acggcacccg
    31681 ccggtaagcc gcaggatttc agggcgtcct gaatcaccgc caccgttgca gcgttagtgc
    31741 gacacgtttc tttgccaccg cgcaggatca ccgcattacc ggttttcagg cacagcgaag
    31801 cgacatcaac cgtcacgttc gggcgcgctt cataaatcac gccaataacc cccagcggta
    31861 cgcgacgacg ctcaagacgc aggccgctgt ccagtacgcc gccatcgatt acctgcccca
    31921 ccggatcggc gaggttgcac acctgacgta catcgtcggc aatgcctttc agccgtgcgg
    31981 gcgtcagtgc cagacggtca agcatcgctt cgctaaggcc attggctcgc gcgtcagcaa
    32041 catcctgggc gttagcgttg aggatgattt cgctttgtgc ttccagttca tcggcgattt
    32101 tttccagcac gcgatttttt tcgcggctgg agagttgcgc taatttatac gaggcttgct
    32161 tcgcggcaat gcccatttgt tccagcatca gcctgctcct taacgggtaa tcatgtcatc
    32221 acggtgaacg gcaaccgggc cgtattcata tcccagtatt gcatcaattt cttgcgagtg
    32281 gtgtccggca atacggcgta atgcatcgct gttgtaacga ctgacgccgt gggcgatatc
    32341 gcggccttcg aggttgcaaa tgcggatgac ttcaccacgc gagaaattgc cagtcacgct
    32401 tttaatgcct ttcggcaaca gggagctgcc gcgttccaga atggcggcag ttgccccttc
    32461 atctaccgtg atttcacccg ccggcggcgc accgaaaatc cagcgtttac ggttttcaag
    32521 cggagtcgcc tgggcatgga acagcgtacc gacggaaatg ccttccatca catcaccaat
    32581 aacgcccggc ttgctgcccg cggcaataat ggtgtcgata cccgcacggc aagccacgtc
    32641 agcggcctgc aatttggtac tcatgccgcc agttccgagg cctgaaacgc tgtcaccggc
    32701 aatcgcgcgc agtgcgtcat caatgccgta aacatcttta atcagttctg cctgcggatt
    32761 gctgcgcggg tcagcggtat acaaaccttt ttgatcggtc agcagcaaca gtttatcggc
    32821 acccgcaaga atcgccgcca gcgcagaaag gttatcgtta tcgccgacct taatctctgc
    32881 cgtagcgaca gcatcgttct cattgattac cggaacgata ttgttatcga gcaacgctcg
    32941 cagggtgtcg cgggcgttca ggaagcgttc acggtcttcc atatcagcac gggtcagcag
    33001 catttgcccg acgtgaatgc cataaatcga aaacagctgt tcccacagtt gaatcagtcg
    33061 actctgccct accgccgcca gcagttgttt cgaggcgatg gtcgctggca gttccgggta
    33121 acccaggtgc tcacgtccgg cggcgatcgc gcccgacgtc acaataacaa tccgatgccc
    33181 ggcggcatgt aactgcgcgc actggcgaac aagttcaacg atatgggcac ggttcagacg
    33241 gcgcgatccg cctgttagca cactggtgcc gagttttacc accagcgtct ggctgtcact
    33301 catgattctc tgccattcaa ttttaggaaa aatgatatca aacgaacgtt ttagcaggac
    33361 tgtcgtcggt tgccaaccat ctgcgagcaa agcatggcgt tttgttgcgc gggatcagca
    33421 agcctagcgg cagttgttta cgcttttatt acagatttaa taaattacca cattttaaga
    33481 atattattaa tctgtaatat atctttaaca atctcaggtt aaaaactttc ctgttttcaa
    33541 cgggactctc ccgctgaata ttcgcgcgtt aattaaaatc aggaatgaaa atgaaaaaga
    33601 gcactctggc attagtggtg atgggcattg tggcatctgc atctgtacag gctgcagaaa
    33661 tatataataa agacggtaat aaactggatg tctatggcaa agttaaagcc atgcattata
    33721 tgagtgataa cgccagtaaa gatggcgacc agagttatat ccgttttggt tttaaaggcg
    33781 aaacacaaat taacgatcaa ctgactggtt atggtcgttg ggaagcagag tttgccggta
    33841 ataaagcaga gagtgatact gcacagcaaa aaacgcgtct cgcttttgcc gggttgaaat
    33901 ataaagattt gggttctttc gattatggtc gtaacctggg ggcgttgtat gacgtggaag
    33961 cctggaccga tatgttcccg gaatttggtg gcgattcctc ggcgcagacc gacaacttta
    34021 tgaccaaacg cgccagcggt ctggcgacgt atcggaacac cgacttcttc ggcgttatcg
    34081 atggcctgaa cttaaccctg caatatcaag ggaaaaacga aaaccgcgac gttaaaaagc
    34141 aaaacggcga tggcttcggc acgtcattga catatgactt tggcggcagc gatttcgcca
    34201 ttagtggggc ctataccaac tcagatcgca ccaacgagca gaacctgcaa agccgtggca
    34261 caggcaagcg tgcagaagca tgggcaacag gtctgaaata cgatgccaat aatatttatc
    34321 tggcaacttt ctattctgaa acacgcaaaa tgacgccaat aactggcggc tttgccaata
    34381 agacacagaa ctttgaagcg gtcgctcaat accagtttga ctttggtctg cgtccatcgc
    34441 tgggttatgt cttatcgaaa gggaaagata ttgaaggtat cggtgatgaa gatctggtca
    34501 attatatcga cgtcggtgct acgtattatt tcaacaaaaa tatgtcagcg tttgttgatt
    34561 ataaaatcaa ccaactggat agcgataaca aattgaatat taataatgat gatattgtcg
    34621 cggttggcat gacctatcag ttttaatgga tattgccgga tgtgatacat ccggcacatt
    34681 tcactcacgc cgttaacttc accggttcat cacgaaaatc atccgccggt tccagcttca
    34741 gattcagcgt cgtcagcagt tcacgcagct tctcgtgaaa ctcacgtagg gtgtgctcca
    34801 gtcgttcaac cacttcagtg tcttttaccg gaacactctt ccagtcgcct gctttatcga
    34861 acagaccaaa ctggtaactg taggtaaaac gggattcctg cgcttcaagc tccatccacc
    34921 agccccagaa ctcacgcact tccggtgccg gtttcacgtt gacgcataca gccagacaat
    34981 cgaaaaagaa tcgattatct tcgcacttac cttcacgaat atacgggcct agtgcggtaa
    35041 attttttgat caatctgctc ttcgggtgtc cactcggtaa cgtcattgca atctcctgtt
    35101 gtgatgcaac tgttttacca aattggcaaa ttttagcaaa tttttaacac aaacgttttt
    35161 cgatccagtc tgtgatttcc tgaagacctt tgtcaaaatt ccgatacacc gggttaaatg
    35221 ggatctctaa taatttaccg tcagcagatg atgaggtgat taagcgtgag tcctcttccg
    35281 ggctgaacgg atcgttcttc cagtagcccg ataacattgg cgttgggcag cgacgtccca
    35341 gcaatccttg cacttttaat gaatagcgat tcagctccac gcgcaacgct tcgtcggaag
    35401 catcatgcat ccccaaacga ctcgccagaa cgtcaagata catttccggc acctgttgct
    35461 ggcacttaaa atcactcaac agggtatgaa ctaccggacc aagacaggca accgctttca
    35521 gacgcggcga ttcaaggtat gccagacgca cggcaacgtt agcgccgaaa cggaaaccaa
    35581 aggccgcgac gcgagtgtga tccacccacg gtacgttagg cagcgccttt aagacgtgct
    35641 gatgcaacag gctggagtcc tgggtcagct tccattttga agaaaagccc accgacggca
    35701 tatcaatagt cagcatcgca atgccgcgcg gcgcaaaata acgttcgtac aggctgtaat
    35761 agtccgtctg catcgcatcc agaccaccac acattaatac tgtcgggaac gggccatcgc
    35821 ctttcggcat atgcaaaaag ccggtgatgg gcgcaccgcc gggtacggta aactccatct
    35881 gccgcatcgt gcccggcaga cgctgagcgg cctcttcata ggcgcggttt gacaaagcct
    35941 gcgcttgctc ggccaggtca tctcctttca gatgaggata ggcagcaatg ttatacaacg
    36001 tagccgcatg cagccagtga cgaccactga gttgcggatc ttcttccgca caggcttttt
    36061 gttgccacac catcgcctgg gtggcccact cataaatcca gttgccacca cggtagccaa
    36121 tcacagtatc gtataaatca tcgtcggtac gttcagcatc gctcatcaca atacgtgcct
    36181 ggacgtcgag gatttcacgt gggtcaatac cgcgccagat ccacatcaga cggttaatca
    36241 tgcgatacca gtgagggatg gttttaccat caagagccga ctgcacaggc ggttgtgcgc
    36301 cgtgattaaa gcggcggact agcgtcgagg tttcaggatg tttaaagcgg ggtttgaaca
    36361 gggtttcgct caggtttgcc tgtgtcatgg atgcagcctc cagaatactt actggaaact
    36421 attgtaaccc gcctgaagtt aaaaagaaca acgcccggca gtgccaggcg ttgaaaagat
    36481 tagcgaccgg agattggcgg gacgaatacg acgcccatat cccacggctg ttcaatccag
    36541 gtatcttgcg ggatatcaac aacatagtca tcaaccagcg gacgaccagc cggttttgcg
    36601 aagatggtga caaagtgcgc ttttggatac atttcacgaa tcgcaaccgc agtaccaccg
    36661 gtatccacca ggtcatcaat aacgatgaag ccttcgccat cgccttctgc gcgtttcagc
    36721 actttaagct cgcgctggtt gtcgtgatcg tagctggaaa tacaaacggt atcgacatga
    36781 cgaataccca gttcacgcgc cagtaacgca cccggtacca gaccgccacg gcttacggca
    36841 ataatgcctt tccattgttc agaaggcatc agtcggcttg cgagtttacg tgcatggatc
    36901 tgcaacatgt cccaggtgac gatgtatttt tcgctcatgt gaagtgtccc agcctgttta
    36961 tctacggctt aaaaagtgtt cgaggggaaa ataggttgcg cgagattata gagatctggc
    37021 gcactaaaaa ccagtatttc acatgagtcc gcgtcttttt acgcactgcc tctccctgac
    37081 gcgggataaa gtggtattct caaacatatc tcgcaagcct gtcttgtgtt gacaacattt
    37141 tctgctaacc ctgtgacctg caatactgtt ttgcgggtga tcgacaagga gacttaacgt
    37201 gtctgaactg tctcaattat ctccacagcc gctgtgggat atttttgcca aaatctgttc
    37261 tattcctcac ccgtcctatc atgaagagca actcgctgaa tacattgttg gttgggcaaa
    37321 agagaaaggt ttccatgtcg aacgcgatca ggtaggtaat atcctgattc gtaaacctgc
    37381 caccgcaggt atggaaaatc gtaaaccggt cgtcttgcag gcccacctcg atatggtgcc
    37441 gcagaaaaat aacgacaccg tgcatgactt cacgaaagat cctatccagc cttatattga
    37501 tggcgaatgg gttaaagcgc gcggcaccac gctgggtgca gataacggca ttggtatggc
    37561 gtctgcgctg gcggttctgg ctgacgaaaa cgtggttcac ggcccgctgg aagtgctgct
    37621 gaccatgacc gaagaagccg gtatggacgg tgcgttcggc ttacagagca actggttgca
    37681 ggctgatatt ctgattaaca ccgactccga agaagaaggt gaaatctaca tgggttgcgc
    37741 ggggggtatc gacttcacct ccaacctgca tttggatcgt gaagcggttc cagctggctt
    37801 tgaaaccttc aagttaacct taaaaggtct aaaaggcggt cactccggcg gtgaaatcca
    37861 cgttggcctg ggtaatgcca acaaactgct ggtgcgcttc ctggcgggtc atgcggaaga
    37921 gctggacctg cgccttatcg atttcaacgg tggcacactg cgtaacgcca tcccgcgtga
    37981 agcctttgcg accattgctg tcgcagctga taaagtcgac gccctgaaat ctctggtgaa
    38041 tacctatcag gacatcctga aaaacgagct ggcagagaaa gagaagaatc tggccttgtt
    38101 gctggactct gtagcgaacg ataaagctgc tctgattgcg aaatctcgcg atacctttat
    38161 tcgtctgctg aacgccaccc cgaacggtgt gatccgcaat tccgacgtgg caaaaggtgt
    38221 ggtcgaaacc tccctgaacg tcggtgtggt gaccatgact gacaataacg tagaaattca
    38281 ctgcctgatc cgttcactga tcgacagcgg taaagactac gtggtgagca tgctggattc
    38341 gctgggtaaa ctggctggcg cgaaaaccga agcgaaaggc gcatatcctg gctggcagcc
    38401 ggacgctaat tctccggtga tgcatctggt acgtgaaacc tatcagcgcc tgttcaacaa
    38461 gacgccgaac atccagatta tccacgcggg cctggaatgt ggtctgttta aaaaaccgta
    38521 tccggaaatg gacatggttt ctatcgggcc aactatcacc ggtccacact ctccggatga
    38581 gcaagttcac atcaaaagcg taggtcatta ctggacactg ctgactgaac tgctgaaaga
    38641 aattccggcg aagtaattat ttgatttgct gccggatggc gtttaatcgc cttccggcag
    38701 tttcatcctt cattatcctt cgataaaagc catccctgta aatgtccgtc gcgggttgcc
    38761 acgttcaatc tggtgatgga acattcgccg ctgcgatttc agcgccgcgc tattttcctg
    38821 ttgctgctgc tccagcttcc aggcaatcag caatcgcgcc agccgtttgt tagcatgctg
    38881 gctgcgctct gactgaacct tcacgctaat accggatgcc agatgcgtgg cgcgtaccgc
    38941 cgagtcggtt ttattgacat gttgaccgcc cggccccgac gaacgcagcg tctcataacg
    39001 gattgcatcc gattgttcct tctcatcagc ggtaaaacgc ccaatgccca gaaaccagtt
    39061 tttgcgccca tgatgaggcc gatacggact cggacaaatc cactgaatag tgccacacca
    39121 gctttcgctt aatgcccatg cgttatcgcc atccagagaa accagcgccg aacgcagcgt
    39181 gtcagagtag cggcccgttt ctgtttccag caccgttaca gcgacgtctt gtcgggtaaa
    39241 aacgaccaac agagaagaac gctgcgccaa tcgggtagcc gcgtccgggg tgtaaatctg
    39301 gcatccccac tacgcgctgc atgttgggta aatttgccgt ggtgtgtaat tgttggatcg
    39361 ctaaactctc gatccacagg tcatcagatg cgatggtaaa taccgcatcg gataagggac
    39421 gaatatattt gcccatgtac cattccattt atactcgtca tacttcaagt tgcatgtact
    39481 gcgactcgaa ttatttagag tatataaata taaaaatcag gaaatggcag acgaatccag
    39541 ggcaagaaaa aaagaattaa tcctggaaag gtctgcaaag agtcattgat aaaggatttg
    39601 tcatgattta cctccttgca gtttgtggaa taagaaaacg cgcacatacc aggcgggcgt
    39661 tattttcatt gcaagctgga tttaatattg cggtttatat cgcatataaa aattagtaaa
    39721 ccacgttccc cggcattcaa cgcgctgctg cttaactgtc tgaaaaccat aacgttcaaa
    39781 aaagggtttt gcggttatgc tggcgtccac cgtaagttcg gattcagact taatcaaagg
    39841 ttttaacaaa gcgcaggcaa ccccgcggcg ggtgtattca gggtcaacaa ataacatatc
    39901 gatataacgt tcaacgcagg taataaaacc aaccggttgt gcattaatga cggcaacccg
    39961 cacttgtgat ttcgcgagtt tctccttcca gcgagattcg tcaatctgcg cccaggcggc
    40021 aatttgttgt ggtgaataat gctgactgga gatcatcgta accgctctaa tgaaaatagc
    40081 gcatagttgc tgaaaatcgc caggctgata gtctcttatt tgtatgttat tcataatata
    40141 aattcaaaaa cgcatgcgaa acgcttctgc cattttccca attttatgca tttggttgtt
    40201 atctcgagcc tgtttatgag gttcaggttt cagaatggca atgagcaacc atgcttgctc
    40261 atcaaacgca ccctgacaat ataccaaatg cgcttcgtca ttcgttctgc tgaattggcg
    40321 caactgtggc ggaaatggat tattcacatt tgccagatga atatgagcaa ctcgctcaaa
    40381 tttgattaat ggccaggtaa acgagtcgtc gtagagtgca tcgcgaccaa atatatctgg
    40441 caaaacaccg tcacgcttat aggaaataaa atccgccgtt aacgcatcaa gttcctctgc
    40501 tgtaagttgc aggcgaataa gttttgtttt gaatacccgc atccttattc cttaaagtca
    40561 ttgaaatcat catccgtcat atcattaaga tatttttcag ctcggcgtgt aatttcctct
    40621 aatcttgcag cacttggacg gaagcgcgcc tttatgggct ttttctcctc ttgttcagca
    40681 agcatgtcca ttaacgcttc gaatgcgctg gcacttaaga gatatcctgc ggggcgatta
    40741 ttagaaagaa ccgcaaccgg ttgatcaata aagtatttag ctgggttttt acgtaactca
    40801 gtaatattga ccgatttttc agcgagaatt cgatgcatgc agtgatcccc tcataataat
    40861 gcacaccaga atagacataa tagtatacat cataatccca gcaccagttg tctttccatt
    40921 tgcggatcaa gcaacgtcac atgcagcccc accagtcgca caccgcgccc gccgcggcgt
    40981 tcatcccagg ttttacgcgc ggtggcgatt aagtcagctt tattcagccg cggccagacg
    41041 tgctcctgag tggtttgctg aaaatcgtcg aactttaatt tcaccccctg gcgggcaatc
    41101 agtaaatcag gttttacctt tgccagacgg cgttcaagtt ccggatacag ccgctcgata
    41161 atcgcttcac attcagacca gtggtggata tcttccgcca tcgtgcgttc cacgccgacg
    41221 gattttcgca accgttcgct gttaacgtcg cgctcgtcaa tcccctgact acgctcccac
    41281 aaaatgcggc caaatttgcc aaagcgttta agcagcatca ccagatcaca cttttgtaca
    41341 tcaccgcagg ttcgtagccc catcgcttcc agttttgccg ccgagacttt gccgacgccg
    41401 gggatttttg ccagtggtaa ggtttgtaaa aatgccggaa cttctgccgg cgtaatcaca
    41461 aactggccgt tgggtttatt catgtcggag gcgattttgg cgagaaactt tacgggtgcc
    41521 acgcccgcag acgccgtcag ttgcagctcg ttgaaaatcg tctggcggat ttcctgggcg
    41581 atgagggtcg cagaaccgtg gcaatggacg ctatcggtga cgtcgagata agcctcatcc
    41641 agtgacaacg gttcaatacg cgaggtgtag cgcgagaaga tttcgcggat atgatttgag
    41701 gcttctttgt aggcgtcaaa gcgccccgga agcaaggtga gatgcgggca taatttgagc
    41761 gccatccctg tcggcatagc gctacgtacg ccaaatttac gcgcgggata attggcggtg
    41821 ctgatcaccc cccgacgttc gcggctgccg ccaatagcaa tagggatatc gcgcagggcg
    41881 ggattgtcgc gcatctccac tgcggcgaaa aagcagtcca tatccacatg aatgatttta
    41941 cgcattactc acctctcaac actggtaaag tatacagtga tttcagggtt tgagaaatgc
    42001 gtaaagattc agcatttagc gcgttcgctg cgaaagcacc tgctgcttat ccagcttttg
    42061 caccagcggc tgcaccactt tatccccatg ctgaccaaag tattgataca gcgtatcgga
    42121 cgcacttttg gtcagcacca taatctcgat gcgccgatta cccgcacttt gcggattctt
    42181 cgcgtccagc agcatctggt ccgccattgc gcttacctgc atcactttat cttccggcat
    42241 tccggcctct tccagcaccc gacgagccga aagcgcgcgg tcacccgaaa ggttccagtt
    42301 gttgtagata ttgtttttgt aggccatcgc atcggtatgc ccggtaataa taattttatt
    42361 atcgagcgag tcgaacactg gcgcgagctc caccagcagc gttttaaaga acggcataat
    42421 cttcgcgctg ccgcgttcaa acatattgcg gttctggtca tctttaatca gcacgcgcaa
    42481 tccctgggga acaatctcca tctccagatt cgcttccata tgcgcatcac gggcaatggt
    42541 gttgatactg gttgccagct cgccaagctc ggtggcggat ttcttcttca gcagcgctgt
    42601 tttctcgttg acgtctcgcg cttttttctc cgtctcttcc ggcaccgcca cggtggcagg
    42661 ttttggcgga tgagacgggc tgattttatt taacggcgac aatccgccgc cactgaaaat
    42721 cgactgcccg tgcagcgcgg cgataatgct ttcacgctcg gatttactga cgctgttgac
    42781 aatcaacttt attgtcgtca ccaaaggggc cgagcgtatt tccgaggttt ctgcccgctt
    42841 taccttagac gcgatgcccg gcaaacagat ggcgattgac gccgatctta acgccggatt
    42901 gatcaaccag gcgcaggcgc aaacccggcg taaagatgtt gccagcgagg ccgatttcta
    42961 cggcgcgatg gacggggcat cgaagtttgt gcgcggggac gccatcgccg ggatgatgat
    43021 tctggcgatc aacctgatcg gcggcgtctg tatcgggatc ttcaaataca acctgagcgc
    43081 cgatgctgcc ttccagcagt atgtgctgat gaccatcggc gacggcctgg tggcgcagat
    43141 cccttccctg ctgctctcca ccgcggcggc gattatcgtc acccgcgtca gcgacaacgg
    43201 cgatatcgcc catgacgtgc gtaaccagct gctggcaagc ccgtcggtgc tctacaccgc
    43261 caccgggatt atgttcgtgc tggcggtggt accgggaatg ccgcacctgc cgtttttgct
    43321 gttcagcgcc ctgcttggtt ttaccggctg gcggatgagc aaacagccgc tggcggcgga
    43381 ggcggaagag aaaagcctcg aaacgctgac ccgcaccatc accgaaacca gcgagcagca
    43441 ggtcagttgg gaaaccattc cgctgatcga gcctatcagt ttaagcctcg gttacaaact
    43501 ggtggcgctg gtggacaaag cacagggtaa cccgctcacc cagcggattc gcggcgtgcg
    43561 gcaggtgatt tctgacggca acggcgtgct gctgccggag atccgcattc gggaaaactt
    43621 ccgccttaag cccagtcagt acgccatttt catcaacggc ataaaggctg atgaagcgga
    43681 tattccggcg gataaactga tggccctgcc ctccagcgaa acctacggcg agattgacgg
    43741 cgtgcagggg aacgacccgg cgtacgggat gccggtcacc tggatccagg cggcgcagaa
    43801 agcgaaggcg ctgaatatgg ggtatcaggt gatcgacagc gccagcgtga tcgctaccca
    43861 tgtaaataag attgtgcgca gctatattcc tgatttgttt aactatgatg atattacgca
    43921 gttgcataac cgtttatcgt cgacggcacc gcgtctggcg gaagatttga gcgcggcgct
    43981 caattacagc cagttgctga aagtgtaccg ggcgctgctg accgaaggcg tttccctgcg
    44041 cgatatcgtc accatcgcca ccgtgctggt cgccagtagc acggtgacga aagatcatat
    44101 tctgctggcg gccgatgtgc gcctggcatt gcggcgcagc attacccatc cgttcgttcg
    44161 caagcaggag ctgacggtgt atacgctgaa taatgagctg gaaaatctgc tgaccaacgt
    44221 ggtgaatcag gcgcaacagg gcgggaaagt gatgctcgac agcgtgccgg tcgatccgaa
    44281 tatgctcaac cagttccaga gtacgatgcc acaggtgaaa gagcagatga aagcggcggg
    44341 gaaagacccg gtgctgctgg tgccaccgca gctgcgccct ttgctggcgc gttatgcaag
    44401 gttgtttgcg ccggggctgc atgtgctgtc gtataacgaa gtgccggatg agctggagtt
    44461 gaagattatg ggggcgttga tgtaagtatc cagcattggt gcacaactgc cggatgcggc
    44521 gtgaacgcct tatccgtcct accgttcagg cacaagtttg taggcatgat aagacgcgcc
    44581 agcgtcgcat caggcatctg cgcataactg ccggatgcgg cataaacgcc ttatccggcc
    44641 taccgatccg gcacaagttt gtaggcatga taagacgcgc tagcgtcgca tcaggcatct
    44701 gcgcacaatt atgaaatgat acgctccccg gcactaaaat ccgttacgtc ccccgcccaa
    44761 tcgatgggat ataaccctcg cgcgacatcg cgatggaacg ttgagaatgg ccaatcactc
    44821 acttgcttta cccaaccatg ctttactgga tttatataaa tataatcaac atgatgccta
    44881 taatctttgg tattgcggat ggcgtgctcc caaaaacgtg gttgccagat atttttcaat
    44941 ccacaagcat gggtaaattg ctttttaatt tcccgccagc gcgaggaaaa atcatcatcg
    45001 ccttcaggta atgtccagat acagtgcata tgctctggca aaacgaccca ggcgttgatt
    45061 tcaaaaggcc tgtctcgctt aactttaata atggcgtgac ggagcatctg gtactgggtg
    45121 gtcaaaagtt ggcttcgacg atttcgtaaa ttcaccgtga aaaaccatgt tccccccttg
    45181 atgtaataac gacgatattc agacatggcg actccttttt ctcaacggta agaagaaaag
    45241 gaaaggttgg caatgaggtt gttttatatc gggaaagcgg ctcgcaaata ttcgcgggct
    45301 cgtaggcatg ataagacgcg ccagcgtcgc atcaggcacc tgcgtacaac tgccggatgc
    45361 ggcgtaaacg ccttatccgt cctacaaaat cgtctcttcc gtcaaaatcc tgcgcgcgcc
    45421 caaaaaatgg tcctgccaga aaggttcggc taatcggctt atccgaatgg tttcgccggt
    45481 acgtggcgac tcgataaatt gcccatcgcc caaatacacg cccatatgat cggctatctc
    45541 gcggctgtgg atatggaaaa acagcaaatc tccccggcgc aggtcgttgt tcgccacaat
    45601 cgttgcccgg cgatagtggt acatctcatt ggccgtgcgc gggagcttag cctcaaggat
    45661 cttgttgtag gcataaaaaa ccaacccgct acagtcaaag cctttatcag gccgcgtacc
    45721 gccccagacg taaggcttgc caagctgctg ctccaggcgg tgaatcgcca cttcggtaat
    45781 gttatgcaga tggtcgctgc ttaaaaagtg gttgttttcc gccagcgcct gccagcgtct
    45841 gtcactcgcc ttgagcggag caggaaacca ttctggatgc tgttttatct gctcctggtt
    45901 gtgctggcgt agcgcccttt tgctttcggc attgccttcc acaatatagc tggcctgctt
    45961 tttcagatga gtttggtact gttttaataa acgcgcacgg ttttgcatcc gctggcgggc
    46021 ggcgtagctg aaagagatat gtgatgtggt ggcgctggca aatgaagaaa acggcaaaca
    46081 aatcaacagt aatcccgaca atacaaagga tggaatcgac ggcaaggaca tactcaataa
    46141 tggctggtca tgctttaatg ttgcagtgta tcccggatcg tttctgaaca aacttaataa
    46201 accattatta taaaattaac atatatattt cagttaatta tgtaaaaaca tccgtttatt
    46261 aaattactca tggattgtcg ctgttgctca tttgagctac aattcaagct gaataaatat
    46321 acagcacagg agatacccca atggctgcta acgcgtttgt tcgcgcccga atcgatgaag
    46381 atctgaagaa tcaggcagcg gacgtactgg ccgggatggg gctgaccatc tctgacctgg
    46441 ttcgcataac cctcacaaag gtcgcgcgtg aaaaggcatt gccgtttgat ttacgcgagc
    46501 ctaatcaatt aaccattcaa tcaatcaaaa acagcgaagc tggcattgat gttcataagg
    46561 ccaaagacgc cgatgattta tttgataaat taggaattta aatatgattc aaagggatat
    46621 tgaatactcg ggacaatatt caaaggatgt aaaacttgca caaaagcgtc ataaggatat
    46681 gaataaattg aaatatctta tgacgcttct tatcaataat actttaccgc ttccagctgt
    46741 ttataaagac cacccgctgc aaggttcatg gaaaggttat cgcgatgctc atgtcgaacc
    46801 ggactggatc ctgatttaca aacttaccga taaactttta cgatttgaga gaactggaac
    46861 tcacgcggcg ctctttgggt aaagcccgct tccgatgaaa tttgtaaacc ctgcgccgac
    46921 aggcttgcgt aaaactcttt tggtgataat gtgagccttc caaatccaga ctattccgat
    46981 ttgggatcca ttttgccgtc ctggcgtgtg taaccgtttt atcaaggaat aagcagtatg
    47041 cgtaaaatcg cattaattct tgcgatgttg ttgatcccgt gcgtttcatt tgccggtttg
    47101 ctgggcagca gtagctctac cacgcctgtg agcaaagagt ataagcagca gttgatggga
    47161 tcccctgtct acatccagat cttcaaggaa gaacgtacgc tcgatctcta cgtcaaaatg
    47221 ggcgagcaat atcaactgct cgacagctat aaaatctgta aatattccgg cggcttaggg
    47281 ccaaaacagc gtcagggcga tttcaaaagc ccggaagggt tttatagcgt ccagcgtaat
    47341 cagttaaaac cagacagccg ttactacaaa gcgattaata ttggtttccc caatgcctat
    47401 gaccgtgcgc atggttatga agggaaatac ctgatgatcc acggcgattg tgtttccatc
    47461 ggctgctacg caatgaccaa tcagggtatt gatgagatat tccagttcgt tactggtgcg
    47521 ctggtgtttg gtcagccgag cgtgcaagtg agtatttacc cgttccgcat gaccgacgcc
    47581 aatatgaagc gccataaata ttccaacttt aaggacttct gggagcaact gaagccgggt
    47641 tacgactact ttgagcaaac ccgtaagcca ccaaccgttt ctgtggtcaa tggtcgttac
    47701 gtggtcagca agccgttaag ccacgaagtt gtgcagccac aactggcatc aaactacacg
    47761 ctccccgagg caaaataagc gccattcgcc tggcataatc ttttgccagg tttcattgcc
    47821 cgtcagcggc tgtgttgcaa tcaccgtgac cacatcattc ggtgtggtct gcgagctgaa
    47881 gtcgatttcc acatcctgat ccagcaacgt tgccacgcca aacggcgcgc ggcgggtgat
    47941 ccagtgtaaa ttagtcgagc aatacgccat tacatagcgc ccgtccgaaa gcagcatgtt
    48001 gaaaacgccc ttctgccgca gttcatccgc cagtgaggcg atatatttaa ataccgccgc
    48061 catgttgccc ggtgtgcgcg ggtaacgctg cgttaattta tgcaggagcc agcagaaggc
    48121 tttttcgctg tcggtttcgc ctaccgggcg gaagttgccg gtttccagtg atttgtagcc
    48181 cgtcagttgt ccgttatggg cataagtcca gttacgcccc cataactcgc gggtaaatgg
    48241 gtgagtattt tccagcgcca cctcgccccg attagcctgg cgaatatgag ccaccaccga
    48301 acaggatttt atcgggtagt cctggacaag tttggcgatg ggggaattaa agctgggttg
    48361 tggatcttta aatgtgcgac agcctttacc ttcgtaaaag gtaatgcccc agccatcttt
    48421 atgtggcccg gttccaccac cacgctgtac aagcccggtg aaactaaagc agatatcggt
    48481 agggacgttg gcgctcatcc cgagcaattc gcacatgggt aacctccaca acagcgggag
    48541 cgcatggccc ccggcgaaga ttgatttaag aattttcagg tcggatgcgg cgtgaacgca
    48601 ttattcggcc tacggttcgc gtacagattt gtaggcatga taagacgcgt cagcgtcgca
    48661 tcaggcatca gcgcacaaat gccggatgcg gcgtaaacgt cttatccggc ctacgccaga
    48721 cttacttaac catctctttt tcaatcaact ggatcaggat atggatcact ttaatgtgaa
    48781 tctcctgaat gcggtcggca taaccaaagt gcggtacgcg aatttcgata tccgccgtgc
    48841 cagccatttt gccgccgtct ttaccggtca gggtgatcac tttcattccc ttctcacgcg
    48901 ccgctgcgat cgctttgatc acgtttgcag agttaccgga ggtggagatc cccagcagta
    48961 catcgccttc gcgacctacc gcttcaacgt agcgggagaa aatatcattg aaaccgaaat
    49021 cattaccgac gcaggaaata tgactaacgt cagaaatagc aatcgccggg tagcccggac
    49081 ggttttcacg gtagcgaccg gtcaactctt cggcaaagtg catagcgtcg caatgggaac
    49141 cgccgttgcc gcaggaaagc actttgccac cggctttaaa gctgtctgct aacaggaccg
    49201 ccgcgcgctg aatggcgtga atattggcgt catcttttaa aaagttagcc agcgtttccg
    49261 ccgcttcgtt cagttcgtta cgaataagat cctggtacat gaggatatcc ttcagcataa
    49321 atgtaataga caaaatgcag tgtaccggat accgccaaaa gcgagaagta cgggcaggtg
    49381 ctatgaccag gactttttga cctgaagtgc ggataaaaac agcaacaatg tgagctttgt
    49441 tgtaattata ttgtaaacat attgctaaat gtttttacat ccactacaac catatcatca
    49501 caagtggtca gacctcctac aagtaagggg cttttcgtta tgatgatttt gagtattctc
    49561 gctacggttg tcctgctcgg cgcgttgttc tatcaccgcg tgagcttatt tatcagcagt
    49621 ctgattttgc tcgcctggac agccgccctc ggcgttgctg gtctgtggtc ggcgtgggta
    49681 ctggtgcctc tggccattat cctcgtgcca tttaactttg cgcctatgcg taagtcgatg
    49741 atttccgcgc cggtatttcg cggtttccgt aaggtgatgc cgccgatgtc gcgcactgag
    49801 aaagaagcga ttgatgcggg caccacctgg tgggagggcg acttgttcca gggcaagccg
    49861 gactggaaaa agctgcataa ctatccgcag ccgcgcctga ccgccgaaga gcaagcgttt
    49921 ctcgacggcc cggtagaaga agcctgccgg atggcgaatg atttccagat cacccatgag
    49981 ctggcggatc tgccgccgga gttgtgggcg taccttaaag agcatcgttt cttcgcgatg
    50041 atcatcaaaa aagagtacgg cgggctggag ttctcggctt atgcccagtc tcgcgtgctg
    50101 caaaaactct ccggcgtgag cgggatcctg gcgattaccg tcggcgtgcc aaactcatta
    50161 ggcccgggcg aactgttgca acattacggc actgacgagc agaaagatca ctatctgccg
    50221 cgtctggcgc gtggtcagga gatcccctgc tttgcactga ccagcccgga agcgggttcc
    50281 gatgcgggcg cgattccgga caccgggatt gtctgcatgg gcgaatggca gggccagcag
    50341 gtgctgggga tgcgtctgac ctggaacaaa cgctacatta cgctggcacc gattgcgacc
    50401 gtgcttgggc tggcgtttaa actctccgac ccggaaaaat tactcggcgg tgcagaagat
    50461 ttaggcatta cctgtgcgct gatcccaacc accacgccgg gcgtggaaat tggtcgtcgc
    50521 cacttcccgc tgaacgtacc gttccagaac ggaccgacgc gcggtaaaga tgtcttcgtg
    50581 ccgatcgatt acatcatcgg cgggccgaaa atggccgggc aaggctggcg gatgctggtg
    50641 gagtgcctct cggtaggccg cggcatcacc ctgccttcca actcaaccgg cggcgtgaaa
    50701 tcggtagcgc tggcaaccgg cgcgtatgct cacattcgcc gtcagttcaa aatctctatt
    50761 ggtaagatgg aagggattga agagccgctg gcgcgtattg ccggtaatgc ctacgtgatg
    50821 gatgctgcgg catcgctgat tacctacggc attatgctcg gcgaaaaacc tgccgtgctg
    50881 tcggctatcg ttaagtatca ctgtacccac cgcgggcagc agtcgattat tgatgcgatg
    50941 gatattaccg gcggtaaagg cattatgctc gggcaaagca acttcctggc gcgtgcttac
    51001 cagggcgcac cgattgccat caccgttgaa ggggctaaca ttctgacccg cagcatgatg
    51061 atcttcggac aaggagcgat tcgttgccat ccgtacgtgc tggaagagat ggaagcggcg
    51121 aagaacaatg acgtcaacgc gttcgataaa ctgttgttca aacatatcgg tcacgtcggt
    51181 agcaacaaag ttcgcagctt ctggctgggc ctgacgcgcg gtttaaccag cagcacgcca
    51241 accggcgatg ccactaaacg ctactatcag cacctgaacc gcctgagcgc caacctcgcc
    51301 ctgctttctg atgtctcgat ggcagtgctg ggcggcagcc tgaaacgtcg cgagcgcatc
    51361 tcggcccgtc tgggggatat tttaagccag ctctacctcg cctctgccgt gctgaagcgt
    51421 tatgacgacg aaggccgtaa tgaagccgac ctgccgctgg tgcactgggg cgtacaagat
    51481 gcgctgtatc aggctgaaca ggcgatggat gatttactgc aaaacttccc gaaccgcgtg
    51541 gttgccgggc tgctgaatgt ggtgatcttc ccgaccggac gtcattatct ggcaccttct
    51601 gacaagctgg atcataaagt ggcgaagatt ttacaagtgc cgaacgccac ccgttcccgc
    51661 attggtcgcg gtcagtacct gacgccgagc gagcataatc cggttggctt gctggaagag
    51721 gcgctggtgg atgtgattgc cgccgaccca attcatcagc ggatctgtaa agagctgggt
    51781 aaaaacctgc cgtttacccg tctggatgaa ctggcgcaca acgcgctggt gaaggggctg
    51841 attgataaag atgaagccgc tattctggtg aaagctgaag aaagccgtct gcgcagtatt
    51901 aacgttgatg actttgatcc ggaagagctg gcgacgaagc cggtaaagtt gccggagaaa
    51961 gtgcggaaag ttgaagccgc gtaaatgaat aacggagccg aaaggctccg tttctttatc
    52021 cgctaattat ttaaaattaa agccatccgg atggttttcc aggctgccgg tcaacgccgc
    52081 gaacaacacc gttttaccat caatcgaaag cgcatcgttc acattcagcc aggtgagttt
    52141 ctcttgcgac gttttctcat caatagtcga gaacagcccc gtcatctgat tagatttctc
    52201 ggaccacatc acagcgatac gttgcgagcc acagtcatgc ggtttgcacg cgctcatcac
    52261 ctgatacgtc tcatctccca acgttacggt ttgtgcggga gtataagtac cgcctttcat
    52321 cacccaggca ggcagcttat gcccttgtac catctgatta aatgcagctt tggtggtttc
    52381 gccctttgca aggctgctaa tggttaaatc atcctgcgcc attgcactgg tggcgatgac
    52441 cagagcggcg actgtcgtta ttgccttaaa catcattcct cccgagctta tcctgcccat
    52501 gttattaacc tcctaaagcc tggcgataac acgataattt gcaaatcaga tatttccaat
    52561 atcagcattt gttatcaatt tattctgcgc taaggcaact gcctgataag gtgttaaagt
    52621 tataaaaccc ttcgcataaa ggagttgtac accgtgcctg gtttgaagat tacgcttttg
    52681 cagcaaccac tggtgtggat ggatggtcct gccaacctgc gtcattttga tcgtcaactg
    52741 gaaggtatta ccgggcgcga tgtgatcgtt ctaccggaga tgtttaccag cggctttgcc
    52801 atggaagcgg cagcttcgtc gctagcacaa gatgacgtag tgaactggat gacagctaag
    52861 gcgcagcagt gcaatgcgct gattgcaggc agtgttgcat tacaaacgga gtctggttcg
    52921 gttaaccgct ttttgctggt tgagccgggc ggcacggtac atttttatga taagcgtcat
    52981 ctgttccgca tggcagatga gcatctacat tataaagcgg gcaatgcgcg agtgattgtg
    53041 gaatggcgcg gctggcgtat tttgccgctg gtgtgctacg acttacgttt tcctgtgtgg
    53101 tcgcgcaatc tcaacgatta tgacctcgcc ctgtacgtcg ccaactggcc tgctccgcgc
    53161 tctctgcact ggcaggcatt gctgacggcc cgcgcgattg agaatcaggc gtatgtggcg
    53221 ggatgcaatc gcgtcggcag cgatggcaac ggctgccatt atcgcggtga cagccgggtg
    53281 attaatccgc aaggagagat tatcgctact gccgacgcgc atcaggcaac gcgcattgat
    53341 gcggagctgt cgatggcagc attgcgggaa tatagagaaa agtttccggc atggcaggat
    53401 gcggatgagt ttaggttgtg gtgagtgggg gttgtgttta aggacgggga gagtcggggt
    53461 attactacga aagcccgctc cccgcaagga ctgacgccag gtagtttctg tccatggctg
    53521 cttttcgcat cttacgtctt aa
//
LOCUS       DAPHKZ010000018        49795 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.018, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000018 DAPHKZ010000000
VERSION     DAPHKZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49795
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.018"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            179..805
                     /locus_tag="RH288_001153"
     CDS             179..805
                     /locus_tag="RH288_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein"
                     /protein_id="HDV4030234.1"
                     /translation="MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQE
                     DIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFG
                     DNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS
                     ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV"
     gene            826..2928
                     /locus_tag="RH288_001154"
     CDS             826..2928
                     /locus_tag="RH288_001154"
                     /EC_number="1.2.7.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase"
                     /protein_id="HDV4030235.1"
                     /translation="MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDE
                     VPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQ
                     MKFAGYDVIIIEEKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
                     AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKR
                     LNDYMMTELIGANNNHVEPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPP
                     GNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGN
                     TCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYS
                     KGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWN
                     LGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPL
                     KLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTV
                     SPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRN
                     EHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQR
                     LGLEDIAADLAAHNLLPA"
     gene            2941..3579
                     /locus_tag="RH288_001155"
     CDS             2941..3579
                     /locus_tag="RH288_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhW family putative oxidoreductase system
                     protein"
                     /protein_id="HDV4030236.1"
                     /translation="MNHQDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAE
                     FIRQHSAAGQLVARAVFLSPPYLVAEEELSVLLESIKQNGDYADIACLTGSKDDYYYS
                     TQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
                     AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP"
     gene            3643..4311
                     /locus_tag="RH288_001156"
     CDS             3643..4311
                     /locus_tag="RH288_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416186.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDV4030237.1"
                     /translation="MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDES
                     RCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCID
                     VCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLA
                     KGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIK
                     KENV"
     gene            4308..5093
                     /locus_tag="RH288_001157"
     CDS             4308..5093
                     /locus_tag="RH288_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HDV4030238.1"
                     /translation="MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVL
                     GLHALLRARGVKKSATDHGEKIYLYSKAVRLWHWSNALLFVLLLASGLINHFAMVGAT
                     AVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGI
                     MQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYW
                     LLQTHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH"
     gene            5097..5909
                     /locus_tag="RH288_001158"
     CDS             5097..5909
                     /locus_tag="RH288_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030239.1"
                     /translation="MIITQADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYT
                     DWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERPFCSQFARSDDHARIGCCED
                     NARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRI
                     ANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTG
                     VVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC"
     gene            complement(5921..7525)
                     /locus_tag="RH288_001159"
     CDS             complement(5921..7525)
                     /locus_tag="RH288_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-NAD(P)-binding protein"
                     /protein_id="HDV4030240.1"
                     /translation="MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPY
                     SDEENSKMMLANIASIEIPPIYCTYLEWLQKQEDSHLQRYGVKKETLHDRQFLPRILL
                     GEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVI
                     ATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFI
                     EDDKQHVVFHRDNASEKLNITLLSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKG
                     EEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNL
                     QEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPS
                     ESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKV
                     KDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTA
                     CAEIGEAMARAVVKPASRARRRLSFD"
     gene            complement(7651..7956)
                     /locus_tag="RH288_001160"
     CDS             complement(7651..7956)
                     /locus_tag="RH288_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDV4030241.1"
                     /translation="MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTES
                     EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA"
     gene            complement(8064..8140)
                     /locus_tag="RH288_001161"
     tRNA            complement(8064..8140)
                     /locus_tag="RH288_001161"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8104..8106),aa:Val,seq:gac)
     gene            complement(8145..8221)
                     /locus_tag="RH288_001162"
     tRNA            complement(8145..8221)
                     /locus_tag="RH288_001162"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8185..8187),aa:Val,seq:gac)
     gene            8529..9785
                     /locus_tag="RH288_001163"
     CDS             8529..9785
                     /locus_tag="RH288_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HDV4030242.1"
                     /translation="MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENT
                     VVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRH
                     PEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGE
                     LLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGT
                     DGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRA
                     PVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDSVTFIVGNINL
                     NGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITD
                     ASRQTLCNALKLQPDEDGIGATLQPA"
     gene            complement(9826..11199)
                     /gene="mdtK"
                     /locus_tag="RH288_001164"
     CDS             complement(9826..11199)
                     /gene="mdtK"
                     /locus_tag="RH288_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HDV4030243.1"
                     /translation="MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLI
                     MLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSM
                     RDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTV
                     SLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITF
                     TAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAI
                     ILQRASR"
     gene            11414..12055
                     /gene="ribE"
                     /locus_tag="RH288_001165"
     CDS             11414..12055
                     /gene="ribE"
                     /locus_tag="RH288_001165"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDV4030244.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAH
                     NGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGH
                     IMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA"
     gene            complement(12095..13243)
                     /gene="cfa"
                     /locus_tag="RH288_001166"
     CDS             complement(12095..13243)
                     /gene="cfa"
                     /locus_tag="RH288_001166"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HDV4030245.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGAR
                     LFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
                     EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTIL
                     LQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLN
                     VDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPE
                     IADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR"
     gene            complement(13534..14745)
                     /locus_tag="RH288_001167"
     CDS             complement(13534..14745)
                     /locus_tag="RH288_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HDV4030246.1"
                     /translation="MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVS
                     ASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRF
                     VQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
                     AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLV
                     LFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAA
                     LQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNH
                     GNAEVAHSESH"
     gene            14858..15790
                     /locus_tag="RH288_001168"
     CDS             14858..15790
                     /locus_tag="RH288_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4030247.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
                     RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     VVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVTLELENPFPDSACCLTWQQND
                     MSPALTWLLEYLGDSETLNKEWLREPEETPATGD"
     gene            complement(15787..16812)
                     /gene="purR"
                     /locus_tag="RH288_001169"
     CDS             complement(15787..16812)
                     /gene="purR"
                     /locus_tag="RH288_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HDV4030248.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
                     NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQ
                     GDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDN
                     VRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADG
                     PFRDYRR"
     gene            17111..17200
                     /gene="ynhF"
                     /locus_tag="RH288_001170"
     CDS             17111..17200
                     /gene="ynhF"
                     /locus_tag="RH288_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein YnhF"
                     /protein_id="HDV4030249.1"
                     /translation="MSTDLKFSLVTTIIVLGLIVAVGLTAALH"
     gene            17366..18535
                     /locus_tag="RH288_001171"
     CDS             17366..18535
                     /locus_tag="RH288_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4030250.1"
                     /translation="MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGM
                     LISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRIL
                     TSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
                     SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMF
                     TLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLL
                     MVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAF
                     NLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS"
     gene            complement(18770..19351)
                     /gene="sodB"
                     /locus_tag="RH288_001172"
     CDS             complement(18770..19351)
                     /gene="sodB"
                     /locus_tag="RH288_001172"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HDV4030251.1"
                     /translation="MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFG
                     SFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA"
     gene            complement(19479..20294)
                     /gene="mepH"
                     /locus_tag="RH288_001173"
     CDS             complement(19479..20294)
                     /gene="mepH"
                     /locus_tag="RH288_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-endopeptidase MepH"
                     /protein_id="HDV4030252.1"
                     /translation="MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKA
                     DKKKSTATTKKTQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASA
                     SFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGG
                     SSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQG
                     RGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR"
     gene            20628..20975
                     /gene="grxD"
                     /locus_tag="RH288_001174"
     CDS             20628..20975
                     /gene="grxD"
                     /locus_tag="RH288_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HDV4030253.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKSEEPDAE"
     gene            complement(21026..25642)
                     /locus_tag="RH288_001175"
     CDS             complement(21026..25642)
                     /locus_tag="RH288_001175"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDV4030254.1"
                     /translation="MADNPDPSSLLPDVFSPATRDWFLRAFKQPTAVQPQTWHVAARS
                     EHALVIAPTGSGKTLAAFLYALDRLFREGGEDTREAHKRKTSRILYISPIKALGTDVQ
                     RNLQIPLKGIADERRRRGETEVNLRVGIRTGDTPAQERSKLTRNPPDILITTPESLYL
                     MLTSRARETLRGVETVIIDEVHAVAGSKRGAHLALSLERLDALLHTSAQRIGLSATVR
                     SASDVAAFLGGDRPVTVVNPPAMRHPQIRIVVPVANMDDVSSVASGTGEDSHAGREGS
                     IWPYIETGILDEVLRHRSTIVFTNSRGLAEKLTARLNELYAARLQRSPSIAVDAAHFE
                     STSGATSNRVQSSDVFIARSHHGSVSKEQRAITEQALKSGELRCVVATSSLELGIDMG
                     AVDLVIQVATPLSVASGLQRIGRAGHQVGGVSKGLFFPRTRRDLVDSAVIVECMFAGR
                     LENLTPPHNPLDVLAQQTVAAAAMDALQVDEWYSRVRRAAPWKDLPRRVFDATLDMLS
                     GRYPSGDFSAFRPKLVWNRETGILTARPGAQLLAVTSGGTIPDRGMYSVLLPEGEEKA
                     GSRRVGELDEEMVYESRVNDIITLGATSWRIQQITRDQVIVTPAPGRSARLPFWRGEG
                     NGRPAELGEMIGDFLHLLADGAFFSGTIPPWLAEENTIANIQGLIEEQRNATGIVPGS
                     RHLVLERCRDEIGDWRIILHSPYGRRVHEPWAVAIAGRIHALWGADASVVACDDGIVA
                     RIPDTDGKLPDAAIFLFEPEKLLQIVREAVGSSALFAARFRECAARALLMPGRTPGHR
                     TPLWQQRLRASQLLEIAQGYPDFPVILETLRECLQDVYDLPALERLMRRLNGGEIQIS
                     DVTTTTPSPFATSLLFGYVAEFMYQSDAPLAERRASVLSLDSELLRNLLGQVDPGELL
                     DPQVIRQVEEELQRLAPGRRAKGEEGLFDLLRELGPMTVEDLAQRHTGSSEEVASYLE
                     NLLAVKRIFPAMISGQERLACMDDAARLRDALGVRLPESLPEIYLHRVSYPLRDLFLR
                     YLRAHALVTAEQLAHEFSLGIAIVEEQLQQLREQGLVMNLQQDIWVSDEVFRRLRLRS
                     LQAAREATRPVAATTYARLLLERQGVLPATDGSPALFASTSPGVYEGVDGVMRVIEQL
                     AGVGLPASLWESQILPARVRDYSSEMLDELLATGAVIWSGQKKLGEDDGLVALHLQEY
                     AAESFTPAEADQANRSALQQAIVAVLADGGAWFAQQISQRIRDKIGESVDLSALQEAL
                     WALVWQGVITSDIWAPLRALTRSSSNARTSTRRSHRARRGRPVYAQPVSPRVSYNTPN
                     LAGRWSLLQVEPLNDTERMLALAENMLDRYGIISRQAVIAENIPGGFPSMQTLCRSME
                     DSGRIMRGRFVEGLGGAQFAERLTIDRLRDLATQATQTRHYTPVALSANDPANVWGNL
                     LPWPAHPATLVPTRRAGALVVVSGGKLLLYLAQGGKKMLVWQEKEELLAPEVFHALTT
                     ALRREPRLRFTLTEVNDLPVRQTPMFTLLREAGFSSSPQGLDWG"
     gene            complement(25735..26382)
                     /gene="rnt"
                     /locus_tag="RH288_001176"
     CDS             complement(25735..26382)
                     /gene="rnt"
                     /locus_tag="RH288_001176"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HDV4030255.1"
                     /translation="MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKV
                     VRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
                     QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLSAAEEV"
     gene            complement(26485..26892)
                     /gene="gloA"
                     /locus_tag="RH288_001177"
     CDS             complement(26485..26892)
                     /gene="gloA"
                     /locus_tag="RH288_001177"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDV4030256.1"
                     /translation="MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGP
                     VKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN"
     gene            complement(26973..28070)
                     /gene="nemA"
                     /locus_tag="RH288_001178"
     CDS             complement(26973..28070)
                     /gene="nemA"
                     /locus_tag="RH288_001178"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-ethylmaleimide reductase"
                     /protein_id="HDV4030257.1"
                     /translation="MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEV
                     VDAGIEEWGADRIGIRVSPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDW
                     AGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLV
                     ARLQRKAELNPQRAESFYGGGAEGYTDYPTL"
     gene            complement(28107..28706)
                     /gene="nemR"
                     /locus_tag="RH288_001179"
     CDS             complement(28107..28706)
                     /gene="nemR"
                     /locus_tag="RH288_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416166.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NemR"
                     /protein_id="HDV4030258.1"
                     /translation="MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGS
                     FYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGT
                     ISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQA
                     QVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV"
     gene            28809..29048
                     /locus_tag="RH288_001180"
     CDS             28809..29048
                     /locus_tag="RH288_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HDV4030259.1"
                     /translation="MAEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSD
                     GEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF"
     gene            29097..29993
                     /locus_tag="RH288_001181"
     CDS             29097..29993
                     /locus_tag="RH288_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HDV4030260.1"
                     /translation="MVQRITIAPQGPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAREENVIGHYITD
                     RDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVADAFKHLHQSGKVRHFGVSNF
                     TPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLF
                     NDDYFQPLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAE
                     TLKMTRQQWFRIRKAALGYDVP"
     gene            30074..30595
                     /gene="sodC"
                     /locus_tag="RH288_001182"
     CDS             30074..30595
                     /gene="sodC"
                     /locus_tag="RH288_001182"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HDV4030261.1"
                     /translation="MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTIT
                     ETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKDGKASAAESAGGHLDPQNTGKHE
                     GPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEIKDKALMVHVGGDNMSDQPKPL
                     GGGGERYACGVIK"
     gene            complement(30596..32608)
                     /locus_tag="RH288_001183"
     CDS             complement(30596..32608)
                     /locus_tag="RH288_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDV4030262.1"
                     /translation="MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSA
                     WLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWQPETTDAIRAAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPGATREIL
                     EQLLTALASSQTDVYTVARIIAPLRPTNVADYRHVAFWQRLRYFCRLYLQSSQELHRL
                     QSGVDDHTRLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLA
                     AISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLAT
                     MQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFA
                     ILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARR
                     WLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATL
                     EELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS"
     gene            complement(32608..33465)
                     /locus_tag="RH288_001184"
     CDS             complement(32608..33465)
                     /locus_tag="RH288_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416161.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDV4030263.1"
                     /translation="MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQ
                     VSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKAN
                     NEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSG
                     WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKT
                     LQGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSG
                     TTCSIAVGQ"
     gene            complement(33468..33704)
                     /locus_tag="RH288_001185"
     CDS             complement(33468..33704)
                     /locus_tag="RH288_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HDV4030264.1"
                     /translation="MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLL
                     RGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW"
     gene            33905..34339
                     /gene="slyA"
                     /locus_tag="RH288_001186"
     CDS             33905..34339
                     /gene="slyA"
                     /locus_tag="RH288_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HDV4030265.1"
                     /translation="MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLP
                     PDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISE
                     MEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG"
     gene            complement(34386..34853)
                     /gene="slyB"
                     /locus_tag="RH288_001187"
     CDS             complement(34386..34853)
                     /gene="slyB"
                     /locus_tag="RH288_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HDV4030266.1"
                     /translation="MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGT
                     IVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTVGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSPGQRVVLASNGSQVTVSPR"
     gene            35127..36236
                     /gene="anmK"
                     /locus_tag="RH288_001188"
     CDS             35127..36236
                     /gene="anmK"
                     /locus_tag="RH288_001188"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDV4030267.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSL
                     KQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVW
                     HEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
                     ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGK
                     VILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAV
                     TISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP"
     gene            36334..36663
                     /gene="mliC"
                     /locus_tag="RH288_001189"
     CDS             36334..36663
                     /gene="mliC"
                     /locus_tag="RH288_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416156.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
                     /protein_id="HDV4030268.1"
                     /translation="MTMKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTV
                     KLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNC
                     QLQNPQR"
     gene            36722..37378
                     /gene="pdxH"
                     /locus_tag="RH288_001190"
     CDS             36722..37378
                     /gene="pdxH"
                     /locus_tag="RH288_001190"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HDV4030269.1"
                     /translation="MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACE
                     AKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLL
                     FPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
                     "
     gene            37507..38781
                     /gene="tyrS"
                     /locus_tag="RH288_001191"
     CDS             37507..38781
                     /gene="tyrS"
                     /locus_tag="RH288_001191"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDV4030270.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVD
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQS
                     DPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK"
     gene            38840..39703
                     /gene="pdxY"
                     /locus_tag="RH288_001192"
     CDS             38840..39703
                     /gene="pdxY"
                     /locus_tag="RH288_001192"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase"
                     /protein_id="HDV4030271.1"
                     /translation="MMKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNH
                     TQYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKA
                     ANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNN
                     VEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQ
                     PVGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIA
                     KPEHYFSATKL"
     gene            complement(39747..40352)
                     /gene="gstA"
                     /locus_tag="RH288_001193"
     CDS             complement(39747..40352)
                     /gene="gstA"
                     /locus_tag="RH288_001193"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HDV4030272.1"
                     /translation="MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF
                     AVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIA
                     TELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFT
                     VLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK"
     gene            complement(40458..41960)
                     /gene="dtpA"
                     /locus_tag="RH288_001194"
     CDS             complement(40458..41960)
                     /gene="dtpA"
                     /locus_tag="RH288_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HDV4030273.1"
                     /translation="MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
                     IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINY
                     RNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMI
                     VAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNPFWIIIGSP
                     ILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDP
                     LMSLEVYGRVFLQIGVATAVIAVLMLLTAPKLHRMTQDDAADKAAKAAVA"
     gene            complement(42571..43206)
                     /gene="nth"
                     /locus_tag="RH288_001195"
     CDS             complement(42571..43206)
                     /gene="nth"
                     /locus_tag="RH288_001195"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDV4030274.1"
                     /translation="MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATD
                     VSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI"
     gene            complement(43206..43901)
                     /gene="rsxE"
                     /locus_tag="RH288_001196"
     CDS             complement(43206..43901)
                     /gene="rsxE"
                     /locus_tag="RH288_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxE"
                     /protein_id="HDV4030275.1"
                     /translation="MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
                     ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRAEAA
                     AERALPNGETGNV"
     gene            complement(43905..44525)
                     /gene="rsxG"
                     /locus_tag="RH288_001197"
     CDS             complement(43905..44525)
                     /gene="rsxG"
                     /locus_tag="RH288_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HDV4030276.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKA
                     LFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSG
                     AIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE"
     gene            complement(44529..45587)
                     /gene="rsxD"
                     /locus_tag="RH288_001198"
     CDS             complement(44529..45587)
                     /gene="rsxD"
                     /locus_tag="RH288_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HDV4030277.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTL
                     VQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGT
                     VFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
                     VIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGA
                     GWQWVNLAWLAGGVWLLWQKAIRWHIPLSFLVTLALCAMLGWLFSPETLAAPQIHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(45588..47810)
                     /gene="rsxC"
                     /locus_tag="RH288_001199"
     CDS             complement(45588..47810)
                     /gene="rsxC"
                     /locus_tag="RH288_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDV4030278.1"
                     /translation="MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFV
                     IPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSA
                     LAELSVIIDADGEDCWIPRDGWADYRTRSREELIERIHQFGVAGLGGAGFPTGVKLQG
                     GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKP
                     QAISMLRAVLADSNDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLL
                     PQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEE
                     KRAAEAKARFEARQARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQAT
                     QPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARA
                     KARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQANAEPEEQVDPRKAAVE
                     AAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKREQQPANAEPEEQVDP
                     RKAAVEAAIARAKARKLEQQQANAVPEEQVDPRKAAVAAAIARAQAKKAAQQKVVNED
                     "
     gene            complement(47803..48381)
                     /gene="rsxB"
                     /locus_tag="RH288_001200"
     CDS             complement(47803..48381)
                     /gene="rsxB"
                     /locus_tag="RH288_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HDV4030279.1"
                     /translation="MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEIL
                     PQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQE
                     ITPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA"
     gene            complement(48381..48962)
                     /gene="rsxA"
                     /locus_tag="RH288_001201"
     CDS             complement(48381..48962)
                     /gene="rsxA"
                     /locus_tag="RH288_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDV4030280.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRL
                     LGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            complement(49039..49479)
                     /locus_tag="RH288_001202"
     CDS             complement(49039..49479)
                     /locus_tag="RH288_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HDV4030281.1"
                     /translation="MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTF
                     QTLGGQALTTQILWGVSFITAIALWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAV
                     KAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP"
     gene            complement(49565..49780)
                     /gene="ydgT"
                     /locus_tag="RH288_001203"
     CDS             complement(49565..49780)
                     /gene="ydgT"
                     /locus_tag="RH288_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HDV4030282.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAAD
                     HRRAELVSGGRLFDLGQVPKSVWHYVQ"
BASE COUNT        12523 a        12408 c        12976 g        11888 t
ORIGIN      
        1 cattattttt tctcctaacc ataaaggatt agtttatcgg cgttaatctt ttctcataca
       61 ctatcgggtt agggaaaata tctggtgttg gggacagagt cagcagcgta ttagttgaat
      121 gcttaatatc aggctgctga attgtcagca ctgtgtttgc gaagaggatg cgaaataaat
      181 gaacccggtt gatcgtccac tattagatat tggcttaacg cgattagaat tcttgcgtat
      241 atcaggaaaa ggccttgctg gtctaacaat tgcccctgcg ttactgtcac ttttgggttg
      301 caaacaggaa gatattgata gcggcacagt agggttgata aataccccca aaggggtgct
      361 ggtgacccag cgagcgcgat gcacgggttg ccaccgctgt gaaatctctt gtaccaactt
      421 caacgatggc tcagtaggga cattcttctc ccgtatcaaa atccatcgca attatttctt
      481 tggcgacaac ggggttggct ctggcggcgg cctgtatggc gatctcaact ataccgcgga
      541 cacctgccgt caatgcaaag agccgcaatg catgaacgtc tgcccgattg gtgcgattac
      601 ctggcagcag aaagaaggct gtattaccgt cgatcataaa cgctgtattg gctgtagcgc
      661 ctgtactacg gcatgcccgt ggatgatggc caccgtaaat accgaaagta aaaaatcctc
      721 gaaatgtgtg ttatgcggtg aatgcgcaaa cgcctgccca acaggggcgt taaaaattat
      781 cgagtggaaa gatattactg tgtgaatctt gcaaaggaaa aaatcatggc taacggttgg
      841 acaggtaata tattaagagt caatctcacg acaggaaata ttaccctcga agattccagt
      901 aagtttaaaa gttttgtcgg tggcatgggc ttcggctaca aaattatgta tgacgaagta
      961 ccgccaggca cgaaaccttt cgatgaagcg aataaattag tctttgctac cggcccatta
     1021 actggatctg gtgccccctg tagttctcgc gtaaatatca cctcactttc tacttttacc
     1081 aaaggaaatt tagtcgtcga tgcccatatg ggtggctttt ttgcagcgca aatgaaattc
     1141 gctggatacg acgtcattat tatcgaagag aaggcgaaat caccggtatg gctgaagatt
     1201 aaagatgaca aagttagcct ggaaaaagcc gatttcttat ggggaaaagg gacgcgcgca
     1261 acgacggaag aaatttgtcg attgaccagt ccggaaacct gtgtggcggc tattggtcag
     1321 gctggggaaa accttgttcc tctctctggc atgttgaata gccgtaacca cagcggcggt
     1381 gcgggaactg gcgcaataat gggttcgaaa aacctgaaag cgattgcggt tgaagggacg
     1441 aaaggggtca acattgccga tcgtcaggag atgaagcgtc tcaatgatta catgatgact
     1501 gaacttattg gtgcgaataa caaccatgtc gagccaagta cgccacaatc gtgggcagag
     1561 tattcagatc ccaagtcacg ctggacagca cgtaaagggc tgttttgggg cgcggctgaa
     1621 ggtggtccga ttgaaacggg tgaaattccg ccaggcaatc agaatacggt cggctttcgt
     1681 acctataaat ccgtttttga cttaggaccg gcggcagaga aatacacagt aaaaatgagc
     1741 ggctgccact cttgcccgat ccgttgtatg acccaaatga atattcctcg ggtgaaagag
     1801 tttggcgtgc ccagcacagg tggtaacact tgtgtagcaa actttgtcca taccaccatc
     1861 ttcccgaacg ggccgaaaga ttttgaagat aaagacgatg gtcgtgtgat tggtaacctg
     1921 gtgggtctga atttgttcga tgactacggc ctatggtgta actacgggca gttgcatcgc
     1981 gactttactt attgttacag caaaggtgtg ttcaagcgtg ttctgccagc tgaagagtat
     2041 gcagaaattc gctgggatca actggaagcg ggtgacgtta acttcattaa agatttttac
     2101 taccgtctgg cgcatcgtgt gggtgagctg agtcacctgg ctgatggttc atatgccatc
     2161 gcagaacgct ggaatttggg tgaagagtac tggggctacg cgaaaaataa actctggtcg
     2221 ccgtttggct atccggttca ccatgccaat gaagcgtcag cgcaggtcgg ttccattgtt
     2281 aactgtatgt tcaaccgtga ctgcatgacg catacccata tcaactttat tggttccggc
     2341 ttgccattga aactgcaacg tgaagtggcg aaagaacttt ttggttctga agatgcttac
     2401 gatgaaacca aaaactacac gccaatcaat gacgcaaaaa ttaaatatgc aaagtggtcg
     2461 ctgttgcggg tctgtttgca taacgccgtc accctgtgca actgggtctg gccaatgacc
     2521 gtttcgccgc tgaaaagccg taattaccgg ggcgatctgg cgcttgaagc caaattcttc
     2581 aaagcgatca ccggcgaaga gatgactcag gaaaaattag atttagctgc agagcgtatt
     2641 tttacgttgc atcgtgccta cacggtaaaa ctgatgcaaa ccaaagatat gcgtaatgaa
     2701 cacgatctta tctgttcctg ggtattcgac aaggatccgc agatcccggt ctttactgaa
     2761 ggtactgaca aaatggatcg tgacgatatg catgcttcgc tcacgatgtt ctacaaagaa
     2821 atgggctggg acccacagct tggttgtcca acccgcgaaa cattgcagcg tctggggctg
     2881 gaagatattg ccgccgatct ggcagcacac aatctactgc ctgcgtaagg aatgggtaag
     2941 atgaaccatc aggatgaatt gccgttagcg aaagtcagcg aagttgacga ggcgaagcgg
     3001 caatggttgc aggggatgcg tcaccccgtt gatacggtaa ccgaaccaga acctgctgaa
     3061 atcctggctg agttcattcg ccagcattct gcggctgggc agctggtggc gcgcgccgtg
     3121 tttctctcgc caccctattt ggttgcagaa gaggaactgt cagttttgct ggaaagcatt
     3181 aagcagaacg gagactacgc ggatatcgct tgtttgacgg gaagcaagga tgattactat
     3241 tactcaacgc aggccatgag tgaaaactac gcggcgatgt ctttgcaagt tgtggagcag
     3301 gacatttgtc gcgccattgc acacgccgtt cgttttgagt gccagacgta tcctcgtcct
     3361 tacaaagtcg ccatgctgat gcaagcgcca tattacttcc aggaagcgca gattgaagcc
     3421 gcgatcgccg cgatggatgt tgcacctgaa tatgccgata tacggcaggt ggagtcatcg
     3481 acggcggtgt tgtacttgtt tagcgagcga tttatgacct atggcaaggc ttatggctta
     3541 tgcgaatggt tcgaggtaga gcagtttcag aacccctgaa atttcaggga gatgtcatgg
     3601 atagggtgga cagttgcagc cactgcatta ggggataatc agatgtcctt cactcgacgc
     3661 aaatttgttc tggggatggg aacagtaatc ttttttactg gttctgcgtc ttctctgtta
     3721 gcgaacacga ggcaagaaaa ggaagttcgg tatgccatga ttcatgacga gtcacggtgc
     3781 aatggctgta atatttgcgc ccgcgcatgc cgtaaaacta accacgtccc cgctcaggga
     3841 agccgtttat cgatagcaca cattccagtc accgataacg acaacgaaac gcagtatcac
     3901 ttttttcgcc agtcatgtca gcactgcgaa gatgctccgt gcatcgacgt ttgcccgacg
     3961 ggggcgtcgt ggcgtgatga gcaggggatc gtgcgggtag aaaaatcgca gtgcatcggc
     4021 tgcagttatt gcattggcgc ttgtccgtac caggttcgct accttaaccc tgtcactaaa
     4081 gtggcagata aatgtgattt ctgcgctgag tcccgactgg caaaaggctt tccgcccatt
     4141 tgcgtcagcg cctgcccgga acacgcattg atctttggtc gcgaagatag cccagaaatt
     4201 caggcgtggt tgcagcaaaa taaatactat caatatcagc tacctggtgc cgggaaaccg
     4261 catctgtatc gccggttcgg tcaacatttg attaaaaagg aaaatgtatg aacccgtcgc
     4321 aacatgctga acagtttcag agccagttag cgaactatgt gccacagttc actcccgaat
     4381 tttggccggt gtggttgatc attgccggag tattgctggt tgggatgtgg ttggtgctgg
     4441 ggctgcatgc cttgcttcgt gctcgtggcg tgaagaaatc agccaccgat catggtgaga
     4501 agatttatct ttacagcaaa gcggtcagat tatggcactg gtcgaatgcg ttactctttg
     4561 tattgttgct ggccagtggg ctgataaatc actttgcgat ggtgggcgca actgcggtta
     4621 aaagtctggt tgcggtgcat gaagtttgcg gatttttgtt actggcatgc tggctcggct
     4681 ttgtgctgat caatgccgtt ggggataatg gtcaccacta tcgcattcgt cgtcaggggt
     4741 ggctggaacg agcggcaaaa caaacgcgat tttatttgtt tggcattatg cagggggaag
     4801 aacatccttt cccggcaaca acccagtcta aatttaatcc cttacagcag gtcgcctatg
     4861 ttggtgtcat gtatggattg ctgccgttgt tactattgac ggggctgctg tgtctctatc
     4921 cgcaagccgt gggagatgtg tttcctggcg taagatactg gttattgcag acacattttg
     4981 ctctggcatt tataagcctc ttttttatct tcggtcatct ttatctttgc accacggggc
     5041 gtacgccaca cgaaaccttt aaaagcatgg tcgatggcta tcaccggcac taacgaatga
     5101 tcattacaca agcagacctg cgagaatggc gtatcggagc ggtgatgtat cgctggttcc
     5161 tgcgccattt cccacgcggc ggtagttatg ccgatattca tcatgcactg attgaggaag
     5221 gatatacgga ctgggcggag agtctggttg agtatgcgtg gaaaaaatgg ctggcggatg
     5281 aaaacttcgc gcatcaggaa gtttcctcta tgcaaaaact ggccacagac cccggagaga
     5341 gaccattttg cagtcagttt gcccgcagcg acgatcatgc tcgcatcggc tgttgtgagg
     5401 ataacgccag aatcgcaacc gctgggtatg ccgcgcaaat tgccagtatg ggttatagcg
     5461 tgcggattgg aagtgtcggc tttaacagtc acattggcag ctccggtgaa cgcgcacggg
     5521 ttgctgtaac cggtaattct tcgcggataa gcagcgctgg agatagcagt cggattgcga
     5581 ataccggaat gcgagtacgc gtttgtacat tgggtgaacg gtgtcatgtc gccagtaatg
     5641 gtgacctggt gcaaatcgcc agctttggcg caaacgccag aattgccaac agcggcgaca
     5701 atgtacacat cattgccagc ggtgaaaatt caacggtagt gagcacgggc gtggtcgact
     5761 caattattct cgggccagga ggaagcgccg cactggcata tcatgacggc gaaagagttc
     5821 gcttcgccgt cgccattgaa ggtgaaaaca atattcgagc cggagtccgc tatcgtctta
     5881 atgaacagca tcagtttgtt gagtgctgat agctttacct ttaatcaaac gaaagacgcc
     5941 gacgagcacg ggatgcaggc tttacgaccg cccgagccat cgcctcacca atttctgcac
     6001 atgccgtaag tccctgaacg aaaggctggt cgtgcatcaa ccagggcaac gcgccgaacg
     6061 ctacgcgccc acgaatatct tcgggttgct gtaacgtata atcttcgcca acatcaggga
     6121 tttcatcccc tgttttctgt aattgctcgc gtagcccagg gaaagggata tctttcactt
     6181 taagcggacg ttgtccgcgg gcatcaataa aaacgtcaaa cgagtagctg ttgtcttccg
     6241 ttttcaggac ggtgcgcgac tcattaattt ccattttgta gtcttcaccg agggcgagaa
     6301 tatgaatgat tcccgcttca cgtaaggcaa gtaggcgacg aatagactct gaagggattg
     6361 ccgcataatt atcgatgaaa acccgggcaa ggcctttact gaaccgttta tggtcgtgtt
     6421 cattcagatg tggaacaatt tcctgtacgg cttcatgcag gcgcagaatg acataacgcc
     6481 agggaacagt atgtttttct cgtttattgc gttcgacttc ctggagattt ttttctgccc
     6541 agtcaaatgg gtcgcgttgt ttgcgctcgg caaaccaggc ttgagcaaag gaatcgacat
     6601 tcaggctctc taaggctatg cgttgactcc agtctggatc agcaaacttg atttcctcta
     6661 ctatcaatct aaatacccga tccaaaaggc cctcttcgcc tttttgaatc tcagcattta
     6721 atgcctgatc ggtgacgatg tgtaagggct cgtagggaat agggcaatag aaatcggctt
     6781 cgggtaaaat acccgtgcgc gacaacaacg tgatatttag cttttcactt gcgttatcgc
     6841 ggtgaaaaac gacgtgttgt ttatcatctt caatgaacga accatgctga atagccactg
     6901 ccattgccgc atccagtccg ctcaaggatg ttcccataat acccacgtta cacgcatcga
     6961 cctttgcttc catcaggcct gaccacgggc tgggaaaata cgttcgggtt gcttcttctt
     7021 catcaggcca gacgtgaccc gtggcgatca ccgctaaatc aaacgtctcg ctgggtaaat
     7081 cctgatttgt agcgagcatg acgccagcat ttgtaatttg cagatcggta acctggcatg
     7141 attcataaac agccactgca aatttttgct gtcgtgcctg gtctactagt cgtaaaaatt
     7201 gatcgcggaa atattcgccc agcagaattc gcggtaaaaa ctgacgatcg tgcaaggttt
     7261 cttttttaac gccataacgc tggagatggc tgtcttcttg cttttgtagc cattcgagat
     7321 acgtacaata aatcggcggt atttcaatac tggcaatatt tgccagcatc atttttgagt
     7381 tttcctcatc actgtatggc atcccgacac cggcctcgtc agcctgctcg aagatagaaa
     7441 tagaaagtgg agtttgttgc tgtagaagcg agaataaggt gtagatcccc gtaggcccgg
     7501 cacccacaat agcaattttt ttcattgtta cttacctgta cgcattcttt cgaatttagt
     7561 gttatcagat aagtttggtt gagattttta gaatttgaga aatttcagac agggatgaaa
     7621 agggcgctaa ccgcccttga ttaaattctg tcaggcgagt tttgcctgat tgatttgact
     7681 aagtggctca ttgacatcga aaactttggc gacaacttcc tcaacgccga gatttttcag
     7741 tcgggcagta tgtttttcca gataggcaag ggcgcttttt tcatcagtga aaaggtagat
     7801 cccaccggct tcgtggttct tttcactttc tgtccatacc ttccacagaa aaccaggttc
     7861 ctgattaatc gactcagcaa gtggtttaag ctgctcagcc attgcgtcgc caaatgggcc
     7921 attaaaagca aaatgaagtt gtaacaaagt tgccatagcg attctccttc tgataacgca
     7981 tacgaagaca gtgtaaatct tttaacgtat tggatacaga gaagaaacag agggaaaaag
     8041 gagaagacca gattaagaaa atctggtgcg tccgagtgga ctcgaaccac cgacccccac
     8101 catgtcaagg tggtgctcta accaactgag ctacggacgc aggatggtgc gttcaattgg
     8161 actcgaacca acgaccccca ccatgtcaag gtggtgctct aaccaactga gctatgaacg
     8221 caacgttgta ggtgacaacg gggacgaata ttagcggcag agtgggaagg tggcaagagg
     8281 caaaacgtaa ttttctgcgc tatttcgacc gtttgcagag cttttaagca aattggctat
     8341 attttgttga tttgcaaggg tgatttttat tcaggatcgc atttacatct gatacaaccc
     8401 aataattcgt gtatcagagt ttaaacagag ttgtttgcca ccatctcaaa tctgtcgtgg
     8461 ataaatcctc cgtagccttt acacttaggt agcaataaag gcacacagat gcagcaaagg
     8521 aataaatcat gggatctgat gcgaaaaact tgatgagcga cgggaacgtg caaattgtta
     8581 agaccggcga ggtcattggc gcgacgcaac ttactgaagg cgagttgatt gttgaagctg
     8641 gcggaagagc cgaaaatacc gtggtcacgg gggctggctg gttgaaagtg gcaaccggtg
     8701 ggatcgccaa atgcacacag tacggtaaca atggcacgct atcggtcagc gatggtgcca
     8761 ttgccacaga tattgttcag tccgagggag gcgcaattag tctctctacg ctcgctacgg
     8821 ttaatggccg ccatcccgaa ggtgaattca gcgttgataa aggttatgcc tgcggtttgt
     8881 tgctggaaaa tggcggtaac ctgcgtgtac tggaaggaca tcgcgcggaa aaaatcattc
     8941 tcgatcaaga gggcggcctg ttggttaatg ggacaacctc agcggtcgtg gtagatgaag
     9001 gtggtgaatt gttggtgtat ccaggtgggg aagccagcaa ttgtgagatt aatcagggcg
     9061 gcgtttttat gctggccggg aaagccagtg atacgttgct tgctggtggc accatgaata
     9121 atctcggtgg tgaagactct gacactattg ttgagaatgg atccatttat cgtctgggga
     9181 cggatggcct tcagctctac agttccggta agacgcaaaa cctgtccgtg aatgtgggtg
     9241 gtcgggctga agtgcatgcc ggtacgctgg aaaacgcggt aatacaaggt gggacagtga
     9301 tcctgttgtc acccaccagc gcggacgaaa attttgtcgt agaggaagat cgcgcaccgg
     9361 ttgaactgac cgggagtgtt gcattactgg acggcgcttc aatgattatt ggttatggcg
     9421 cagagctgca acaatcaacg attactgtac agcagggcgg tgtgttgatt ctagacggca
     9481 gtacggtaaa aggtgacagt gtcactttca ttgttggtaa catcaatctg aatggtggaa
     9541 aactgtggct gatcactgat gcggcaacgc atgtgcaact gaaagtgaaa cgcctgcgcg
     9601 gagagggagc gatttgcctg caaaccagtg caaaagaaat ttcacctgac ttcatcaatg
     9661 tgaaagggga agttaccggg gatatacacg ttgagataac agatgccagt cggcaaactc
     9721 tgtgtaacgc tctgaaatta cagccagacg aagacgggat tggcgcaacg ctccagcctg
     9781 cgtaaaaata caggcgcaac ccgtgaaggt tgcgccttgt ctttattagc gggatgctcg
     9841 ttgcagaatg atggctgacg gcagacgttg caggaaccgc atacgcaaca tcatcataat
     9901 ggctgccgac gtcaggccaa taataaagcc tatccagaag cctgctggcc ccataggttc
     9961 aacgaccaga tcggtcagtg ccagaatata gccgcttggc aagcccagca cccagtaagc
    10021 cgtaaaggta atatagaaaa tggaacgcgt atctttataa ccacgcaaaa tcccactgcc
    10081 aatcacctgg attgagtcag aaatctgata taccgccgcc agcaacatca aatgcgcagc
    10141 cagcgttaca acctcgggat tgtcgttgta caacagggcg atttgctccc gcagtgaaac
    10201 cgtgaaaatg gccgtcaggg ttgccataca gacacccacc ataagcccgg tccgcgcagc
    10261 ggtttgcgca tccagcgttg agccctgacc cagacgataa cctacgcgga tagttaccgc
    10321 tgccgccagc gacattggaa gcacgaacat tagtgaacta aagttcaggg caatctggtg
    10381 tcctgcgaca tcaacaatac cgagcggaga cactaacaga gccacgacgg caaacagtgt
    10441 cacttcaaag aacagtgcca gcgcaatcgg caaaccgagt tgaatcagtc gtttcataac
    10501 cgcaggatcg ggttttgcgg tgcctttttc gttacgaata tcgcgcatgg agcgggcgcg
    10561 tttaatgtaa gaaaccatgg caaggaacat gacccaatac accgccgcag tagccacgcc
    10621 acaaccaacg ccaccgagct caggcatacc gaaatgacca taaataaaga tatagttcac
    10681 cgggatgttc accagcaggc cgataaagcc cattaccata cccggcttgg tttttgccag
    10741 accttcacac tggttacggg caacctggaa gaacagatat cccggcgcgc cccacaacaa
    10801 cgcacgcaga taacccacgg ctttgtccgc cagagccgga tcgatgtttt ccatggagcg
    10861 gataatgtaa cctgcattcc acagcaccag cataatgaga acggaaacaa aacctgccag
    10921 ccagaaacct tgtcgcacct gatgcgcaat gcgctcacgt cgaccggaac catttaattg
    10981 cgcgataacc ggcgttaatg ccagcagcag tccgtgacca aagaggatcg ccggaagcca
    11041 gatagaagta ccgatagcga ccgccgccat gtcggtggca ctatagccgc ccgccatcac
    11101 ggtatcgaca aaacccatcg cagtttgggc gatttgcgcg agaatcaccg ggattgctaa
    11161 tgctaataac agacgcgctt cactgatata cttctgcacg tgaacacctt ttatttgtag
    11221 ttatatgaga gactaaaaag ccgcctgaat gggcagcaaa aagaagaagc aggggaaatt
    11281 cagtctattg tagcgaggat ttattaattc tccagtgaaa aaatagccat tcttacccct
    11341 tcactggtaa gggcgttttc cacctgctat tgtgctgaac agaatgtctt aactgatttc
    11401 aggagttgta agtatgttta cggggattgt acagggcacc gcaaaactgg tgtcgattga
    11461 cgagaaacca aattttcgta cgcatgtggt ggagttaccc gaccacatgc tggacggcct
    11521 ggaaaccggt gcttccgtgg cgcataacgg ttgctgcctg accgtgacgg aaattaacgg
    11581 caaccatgtc agttttgacc tgatgaaaga aacgttacgc attaccaatc ttggcgattt
    11641 aaaagtgggg gattgggtaa acgttgagcg tgcggcgaaa ttcagtgatg aaattggcgg
    11701 acacttaatg tcaggtcata ttatgaccac tgctgaagtg gcgaaaatat taacctcaga
    11761 aaataatcgc cagatctggt ttaaagtcca ggatagtcag ttgatgaaat atattctgta
    11821 caaaggattt attggcatcg acggtattag cctgaccgtc ggcgaagtca cgccaacgcg
    11881 tttttgcgtc catttaattc cggaaacact ggaacgcacg actcttggga agaaaaaact
    11941 tggcgcacgc gtcaacattg aaatcgatcc acaaactcag gcagtggtag atacggtaga
    12001 acgtgtgctg gcggcacgag aaaatgccat gaatcaacca ggcacagaag cctgatctga
    12061 aatcgccccc ggagaggggg cgatagaata gcctttagcg agccactcga aggccgtttt
    12121 caacaccgcg tgagaacacg acctgccaga gctgaatatc acgggcgcgg aaagcacctg
    12181 cacaggcatt cagataatag gtaaacattc gtttaaagcg ttcactatag ttatccgcaa
    12241 tttctggcca tgcggcgagg aatcgttcat accacgccat caacgtagta tcgtaatcag
    12301 caccgaagtt atgccagtct tccatcacaa agtggggttc gctggactga gcaatctggc
    12361 gtacagaggg caggcaaccg ttcggaaaaa tatatttatt aatccaggga tcaacattca
    12421 gatcggtttt tttcgaaccg atagtatgga gcaggaatat gccttccggt ttcaaattac
    12481 gatccaccac cgcaaaatag gtatcgtaat ttttcggtcc gacgtgctcg aacatcccca
    12541 cagaaacaat acgatcaaac tggtcgttca ggtcacgata atcttgcagc aaaatggtga
    12601 catccaggcc ttcacagcgt tcctgagcca ttttttgctg ttcggcagaa atggtgacgc
    12661 ccaccacgct tacgtcataa ttagatgcca tgtagtgtgc cagtccgccc cagccgcagc
    12721 caatatccag tacgcgcatc cctggtttta actgcaattt ttcacaaatc attttgagct
    12781 tcgcctgctg ggcagattcc agattatcgg catctttcca gtaagcgcag gaatattgca
    12841 tgaagggatc aagcatgcgg ctgaacaagt cattacccaa atcgtaatgc tctttgccga
    12901 ctatccaggc acgtttttta ctctgcagat tgaagagacg agcgccggca atacgcagcg
    12961 tgtctttgaa atgatggggg agttggttct cgagacctgc gcgtaagact ttgctaaaaa
    13021 acatatccag tcggtcacat tcccaccagc catccatata actttcgcct aaccccaaag
    13081 agccttcttg cagaacgcgt ttaaaaaaat cggggttttt cacacgaata tccgccgggg
    13141 cagaaccgtt aatggctata ccggcacggc taagtaattc gttggcgata cggtaccagt
    13201 tgtcatccgg tacactgact tcttctatac acgatgaact catagtttct ccatcactgg
    13261 tcggtgatca gaaccttaaa acagcgtaga cgctttttgg gctttgtgag aaatctcgca
    13321 gaaaaaaccg cgagtctata atccgacgta gaacagaggg aaaggaggaa cccttgccga
    13381 aatgactatc catagtgagt cgggaacgat cctgtccccg taaaaacata atatttatcg
    13441 tagctttaac aactcgaaat tagtataggc cgctaatttc aatcatacaa caaaattttg
    13501 ttagcagcct aagtataagt atatcgatat agatcagtgt gattcgctat gagcgacttc
    13561 ggcattgcca tgattctggc agccaacttc ttcacaacgt tgcatcatgt aacccagcgc
    13621 gaccagcact actgttgata acatcacgct ggtggtggtg agcaatggcg tgctgatact
    13681 gatcagccag gaaactacca gacttgcgag gaagcacaga cccagttgaa gagtgttctg
    13741 caacgctgcg gcgcgaccag ttgcgtgtgg gaagggacgc agcgcctggg cgacaacaat
    13801 agggtagatc gcgccattgg caatcgccat cacacagaat gggatcagga tttcgaccag
    13861 cgacacatgg ctaatgaagc ccgcagccca ggtcgcaatg acgctgacag caaacagcac
    13921 cagcaaccac ggtaataact gcttgccttg ccatttctgc agcgcggcgc gacagccata
    13981 accaccaatc agaaacgcga tagtttgcgg gacataactt aaaccaataa ctgccgggct
    14041 gtagcccatt tcactaagga tgaacggtga accggtcagc catgcaaaaa aactggctga
    14101 acaggctgcg tatatcagca cgttgccgcg ataggtttta gaacgtagca ggtcggtaaa
    14161 ggtcagacca tcctgactat tgttacgggc cttcgtcgtg ggtttgagcc agaaaatagg
    14221 cagaatcagc accacggtaa tggcaaacag ggtggcgaaa atcgcctgcc aggaaaaatg
    14281 gaccagcagc cagcttccta acagaggagc cagtgccgga gatagaccca ccagcggcat
    14341 gatggtcgca aaaatacggt taactttctg tgaaggataa taatctgtca ctaatgcttg
    14401 ccagataacc gccgcggcgc agacacccac agcctgtaca aaacgcaata ccagcagcgt
    14461 agcggcgttt tctacccaca gcatccccag actacctaac gcaaaaattg tcaggccgat
    14521 taataatacc ggtttacgac cataacggtc ggagagcggc ccccacagaa gctgggctgc
    14581 ggcaaaaccg gcaaggaaca gactaaggct ggcactgaca gcagacgcag gcgtttgcag
    14641 gtcggcctgt atggcggcga aagcaggcag atacatatcg gttgccagaa aaccgagtac
    14701 gctcaaaccc gccagccaga ctaaaaatct tttcccaggt tgcatgtata ttctctaaat
    14761 ctctcaatta aacaccgccg caaagtgtag ggagtgaaat tagtgttgtg aaacggtaat
    14821 atttgatgac tggtttcaaa aattttgcag gcagactatg tggtcagaat attcactcga
    14881 agttgttgat gcggtagcgc gtaatggtag ttttagcgct gcggcacagg agctgcatcg
    14941 cgttccttct gcggtcagct ataccgtgcg tcagctggaa gagtggctgg cggtgccgct
    15001 ctttgaacga cggcaccgtg atgtggagct gaccgctgct ggagcgtggt ttctcaaaga
    15061 agggcgctct gttgtcaaaa aaatgcagat cacccgccag caatgtcagc agatagcgaa
    15121 cggctggcgc ggtcagttag ctatcgcagt ggataatatt gtcaggccag aacgtacacg
    15181 gcagatgatc gttgattttt atcgccattt tgatgatgtc gaacttcttg tctttcagga
    15241 agtgttcaac ggtgtctggg atgcgctttc cgacgggcgc gtggaactgg cgattggcgc
    15301 aacacgcgcg attccggtag gcggtcgtta tgccttccgg gatatgggga tgctaagctg
    15361 gagttgcgtt gttgccagtc accacccgct ggcgttgatg gatggcccgt tcagcgatga
    15421 tacgttgcgc aactggccgt cgttggtgcg cgaagacacc tcgcgaacgc tacctaaacg
    15481 tattacctgg ttgctggata accaaaaaag agttgtcgtg cctgactggg aatcatcggc
    15541 aacctgtatc tcggcaggat tatgcatagg gatggtgcca acacatttcg ccaaaccgtg
    15601 gcttaatgag gggaagtggg taacattaga actggaaaac ccctttccgg attcggcatg
    15661 ttgtctgaca tggcagcaaa atgatatgtc gcctgcgtta acctggttgc ttgagtatct
    15721 cggcgatagt gagacgctga ataaggagtg gctgcgggag ccggaagaga ctcccgcaac
    15781 gggtgattaa cgacgatagt cgcggaacgg gccgtcagcc acggagcggc gttcaatcaa
    15841 gcgcggatgc acttcaatag actgcggttc ttcacgtttg ttgacgatac gatccaacag
    15901 catgttgaac gctgtttcac ccagcgaatc ttttggctga tggatcgtgg tcagcgccgg
    15961 cgtaaaatag cgcgcgttgc gcacgttatc ataaccgatc agcgaaacat cctgcgggac
    16021 gcgcaggccc atttcatcag cagcacaaag tgcgcccatt gccatgatat cgccaccaca
    16081 gaagacggca gtagggcgat gcggctgcga caggatttgc tgcatggcgc gataaccgga
    16141 ttcaggttca aagtcaccct gcacaatcca gctttccggc accttgatca tcgcttcttc
    16201 catcgccttc ataaaaccgg caaggcggcc tgcgccggtg ttacgttcca gcgggccggg
    16261 gatgacgccg atttcgcggt gaccgcgttc aatcagataa cgcccggcca tgtagccgcc
    16321 ttcgaacgcg ttatcaatga ccgcatcggt gaagtcagct tttgcttcac cccagtccat
    16381 gaccaccatt gggatatggc gatactcttc cagcatcgcc agcaacggct ctgggtactc
    16441 agaacacatc accagcagac catcgacgcg tttttgcgcc atcatcgaca gataagcccg
    16501 ctgtttctca agattgttcc acgcattgcc cagaatcagg gtgtaacctt tctggaagca
    16561 atttttttca actgcttcaa tgatctcggc aaaataggcc gcttcgctgc tggtcgccag
    16621 caaaccgata gacttggtgt ggttaacctt caggctacgc gccaccgcgc taggggagta
    16681 gtgtaattct ttaatcgctg cccacacggc gttgcgcgtt tcttcagcga cgaaacgtgt
    16741 tttgttgatc acgtgtgaca cagttgtagt ggaaacgttt gctcgtttcg ctacatcttt
    16801 tattgttgcc attccatttc actccagacc ctaacttcag ctcctgcaaa atcgcaaggt
    16861 aaacgtttgc ctttacacac cttacgcaca acaaaagtgt tgcggtacgc cggaaaaacg
    16921 acacggagcg tcaggaaggg gtcaatggcc agtacgcaaa tagtgtaagc gtggaatttt
    16981 ggccgatctt gacgaaaagg ggaagtggta aaaacactta tcattataaa tgacgggaga
    17041 ttttttcatc acagtgtgta aaaatgcgta atatcacttt ttgtgtggta ataaaaaagg
    17101 agaaaacttg atgagcaccg accttaaatt ttcactggta acaacgatta tcgtcctcgg
    17161 tttgatcgta gccgtgggtt tgactgccgc gctgcactga tttcctctcg agggagcgcg
    17221 ttctccctcg catctccttc ctgtttgtta gcaaaatggc aaaagtgttt tctctttttg
    17281 ttattttcat ttttttgtga ttgctgtcat gctttcgcca ctttaatgaa tatcgcgtaa
    17341 tgacgcgaag aggtggagat aaggcatgaa aattaactat ccgttgctgg cgctggcgat
    17401 tggcgcgttt ggtatcggga caacggagtt ctcgccaatg ggcttgttgc ccgtcattgc
    17461 gcgcggtgtg gatgtctcga ttcccgctgc cggaatgtta atcagtgcct atgcagttgg
    17521 cgtaatggtt ggcgcgccgc tgatgacgct tctactttct catcgtgccc gccgcagtgc
    17581 gttgattttc ctgatggcaa ttttcacgct cggcaacgta ctttccgcca tcgcgccgga
    17641 ttatatgacc ctgatgcttt cacgcatttt gaccagcctg aatcacggag cattttttgg
    17701 tttgggttca gtcgtggccg caagcgtggt gccaaaacat aaacaggcca gcgcagttgc
    17761 cactatgttt atggggttaa ccctggcaaa tatcggtggc gtgccggcgg cgacctggtt
    17821 gggtgaaacc atcggctggc ggatgtcatt tctggcaacg gcggggctgg gagtgatttc
    17881 aatggtaagt ctgttcttct cattacctaa aggtggtgca ggggcacgac ctgaagtgaa
    17941 aaaagagctg gcggtattaa tgcgtccgca ggtgctgtct gcattgctga cgacggtact
    18001 gggagctggt gcaatgttta ctctctacac ctatatctct ccggtactgc aaagtattac
    18061 ccacgcaaca ccggtgttcg tcacggcaat gctggtgctg attggtgtcg gattctctat
    18121 cggtaactat ctcggcggca aactggcaga tcgttcagtt aacggcacgt tgaaaggctt
    18181 tttgttgttg ttgatggtga ttatgctggc aatcccgttc ctggcccgca atgagttcgg
    18241 cgcagctatt agcatggtgg tgtggggcgc agcaaccttt gcggtcgtac cgccgttaca
    18301 gatgcgcgtg atgcgtgtcg ccagtgaagc gccaggtctg tcttcatcag tcaatattgg
    18361 tgcctttaat cttggaaatg cgctgggagc agctgctggt ggtgcggtaa tttccgctgg
    18421 gctgggatac agctttgtgc cggtgatggg agcgattgtc gcgggactgg cattattgct
    18481 ggtgtttatg tcagccagaa aacaacctga aacagtttgc gttgctaaca gctaattaaa
    18541 caaaaacgca gaaggataac cttctgcgtt acagttgctg acaacgtgcg atttatcttg
    18601 ccggatgcgg tgttaacgac tcatccgcgt tgacatgaaa agacgcgtta ggcgtcgtat
    18661 catgcagcgc ttgtcggatg cggcgagtgc cttatccgac ctacatcgat gatccgcgta
    18721 ggcctgataa gcgtagcgct tcaggcaatg ctgcatttgc catcagttat tatgcagcga
    18781 gatttttcgc tacgaattcc cagttcacca gcgcccagaa gtgctccaga tagccaggac
    18841 gtgcattgcg atagtcgatg taataagcgt gttcccagac atcaacggtc agcagcggag
    18901 tcgcatcggt ggtcagcgga gtacccgcgt tagaggttga aacgatagcc agtttgccat
    18961 cgctgttttt caccagccag gtccagccag aaccaaagtt tttgatcgct gcatcagtaa
    19021 actgcgcttt gaaatcggca aagctgccaa aagatgcggc gatagcttca gcgacttttc
    19081 cagtcggttc gccaccggcg ttcggtgcca ggcagttcca gtagaaagta tggttccaga
    19141 cctgagctgc gttgttgaat acgccacctt cagagctgcg aataatctct tccagtgatt
    19201 taccttcaaa cgcggtacct ttaatcaggt tgttcaggtt agtgacataa gtctgatggt
    19261 gcttgccgta gtgatactcg atggtttccg cagaaatgtg cggtgccaga gcatctttag
    19321 catatggtag tgcaggtaat tcgaatgaca ttgctactct cctttattat taatttgcat
    19381 acgtacaata gccttattgt gcgtatggat agggtagcaa attaaaaggt gagacaaaag
    19441 atgaacttac cctgttgccg taacaacagg gtaaagtttt agcgaagtgt ttttggggtc
    19501 attacccgac gagcgccaac atagtggcgc tgccagtagt cttcactgag agaagtgatt
    19561 tgaatttcct gacctgtgcg cggtgactga ataaatttgc cgttgccgac atacacgccg
    19621 acatgatcgg ctgtgccgcg tccctgagta cggaaaaaga ccaggtcgcc gtttttcagt
    19681 tcactacgtt cgattggcgc tgcatcacgc aggtgataca tttcattcgc cgtacgcgga
    19741 atacgaattt tcaccaaatc tttataagcg taataaacca ggccgctgca atcaaaaccg
    19801 gtacgcggtg agctgccacc ccaacgatat ggcttaccaa tttgctgcat cagtttattc
    19861 attgccactt tcgtagcttt ttgcaccttc gctttgtgcg cgtcggcaag agttcctgac
    19921 gcggcatttt tgactttcac acaatgcgat ttatagccct tacgtttggt acacttttcg
    19981 gtaaagctgg ctgaggccgt tttattgacg gcgtgtttgc tgcgagtttt ggcgttttta
    20041 gaagcggtaa tggaagattt tttaacggaa gaagcggttt tgcttttggt cgtactttta
    20101 ctggcggctt ttttcgctgt tttctgggtc tttttggtgg ttgccgtgct tttcttttta
    20161 tctgcttttt tggtgatatg agtggtagca gaactctccc tggcttgctt tgaagcatgg
    20221 gccataggcg ttaaaggcag ggtggtaaaa agtaaagcac agagcgtgat cgaaatacgg
    20281 tttatccgcg ccactgagcg tccctctgtt aaggcaggtc tatcatgcct gcgtctgatt
    20341 tacaaaactt gatgattcta atgcatagaa gaagagaaag ttaatagctt ttattgttaa
    20401 aaaatacgtt tcgttggcga gcgcaaaaaa atgcagcagt gaaagctaaa aatggttata
    20461 aatacgccag tttgccggca tcagagaaga aacgaatatt tgaaatgcaa caaatagagc
    20521 aaagggataa aatagcaaaa gcgtgatgaa aatgttattt tccgatgccg cactgacccg
    20581 ctacaatgtc agattactgc cgtaaagaag tttgaggaag caagacaatg agcaccacta
    20641 tcgaaaaaat ccaacgccag attgctgaaa acccgatcct gctgtacatg aaaggttcac
    20701 cgaaactgcc gagctgcggt ttctctgccc aggcagtcca ggcgcttgcc gcatgtggcg
    20761 aacgttttgc ctatgttgat attctgcaga atccggacat tcgtgcggaa ctgccgaaat
    20821 atgctaactg gccgaccttc ccgcaactgt gggttgacgg cgagctggtc ggcggttgtg
    20881 atatcgtgat cgaaatgtat cagcgtggcg aactgcagca gctgatcaaa gaaactgccg
    20941 ctaaatacaa gtctgaagag ccggacgcgg aataatccgt cctgcaatac tgacggatgc
    21001 gaacgggcat ccgtcagtcc tttctctatc cccaatccag cccttgtggc gaacttgaaa
    21061 atcccgcctc acgcagcagc gtaaacatcg gcgtttgccg gaccggtaga tcattcactt
    21121 ctgttagcgt aaagcgcagc cgtggttcgc gacgcagtgc ggtagtcagc gcgtggaaaa
    21181 cctctggggc gagtaattcc tctttttcct gccagaccag catttttttg ccaccttgcg
    21241 ccagatagag taacaatttg ccgccagaaa cgaccaccag cgcacccgcc cgacgcgttg
    21301 gaaccagcgt tgccggatgt gcaggccagg gcagaagatt tccccacaca ttagccggat
    21361 cgttggcaga gagcgccact ggtgtatagt ggcgcgtttg cgtggcttgt gtcgccagat
    21421 cgcgcaatcg gtcaatagtc agacgttcag cgaattgcgc gccacccaga ccttctacaa
    21481 aacgacctcg cataattcgc ccggagtctt ccatacttcg acaaagcgtt tgcatcgatg
    21541 gaaacccgcc agggatattt tcggctatca ccgcctgacg actgatgatg ccgtagcggt
    21601 cgagcatatt ttccgccagc gccagcatcc tttcggtatc gtttagtggc tccacctgca
    21661 ataacgacca gcgtccagcc agatttggtg tgttgtaaga tacccgcggc gagacgggtt
    21721 gcgcatagac aggacgtcca cgacgagccc ggtgactgcg gcgagttgag gtgcgtgcgt
    21781 tggaactgct gcgggtgagg gcgcgtaacg gtgcccaaat gtcgctggtg atgacgcctt
    21841 gccagaccag cgcccataac gcctcttgca gggcagagag atcaaccgat tcgccgattt
    21901 tgtcgcgtat ccgttggctg atttgttgtg caaaccaggc tcctccgtca gccagaacag
    21961 cgactatcgc ttgttgcagc gccgaacgat tcgcctgatc cgcttcggcg ggagtgaacg
    22021 attctgcagc atattcctgt agatgcagtg ccaccaggcc gtcatcttca cccagttttt
    22081 tttgccccga ccagataacc gcaccggttg ccagtaattc atcgagcatt tctgacgaat
    22141 agtcgcgtac gcgggcaggc aggatctggc tttcccagag tgaggcgggt aaaccgactc
    22201 cggcaagctg ttcgatcacc cgcatcacgc catctacgcc ctcataaacg cctggcgatg
    22261 ttgaggcaaa gagcgccggg ctaccatcgg tggcgggtaa tacgccctga cgttccagca
    22321 gcaatcgcgc ataggtcgtg gctgcaacgg gacgcgtcgc ttctctggcg gcttgcagcg
    22381 agcgcaaacg cagacgacga aatacttcat cgctcaccca gatgtcttgt tgcagattca
    22441 tcaccagacc ctgttcacgc agttgctgaa gctgctcttc gacaatggca ataccgagac
    22501 taaactcatg agccagttgt tcagccgtga ccagagcatg agcccggaga tagcgcagaa
    22561 agaggtcgcg aagcgggtaa ctgactctat gtaaataaat ctctggcaat gactctggta
    22621 gtcgtacgcc gagggcatca cgcagcctgg cggcatcatc catacaggca agacgctcct
    22681 gtccgctaat catcgctggg aagattcgtt ttactgcaag aagattttcc agatacgacg
    22741 caacctcttc actgctgcct gtatgccgtt gcgccaggtc ttcaacggtc attggcccca
    22801 gttcgcgcag caggtcgaac aatccttctt cacctttcgc tcttctgcca ggagccagtc
    22861 gttgcaactc ttcttccacc tggcgaatga cctgcgggtc gagtaattcc cccggatcga
    22921 cctgtccgag tagattgcgc agtaactcgc tgtccagcga cagtacggat gcccggcgct
    22981 ctgccagcgg ggcgtcgctc tggtacataa attccgcgac atagccgaac aataaacttg
    23041 tggcgaaagg cgagggcgta gtggtcgtta catcggatat ttgaatttcg ccaccgttca
    23101 ggcgacgcat caaacgttcc agtgcgggaa gatcataaac atcttgcaga cattcgcgta
    23161 gggtttcgag aatgaccgga aaatccggat atccctgagc gatttccagc aactgactgg
    23221 cgcgcagccg ttgttgccaa agcggggtgc gatggcccgg agtgcgcccc ggcattaata
    23281 atgcccgcgc ggcgcattcg cgaaaacggg cggcgaaaag tgccgagctg cctaccgcct
    23341 cgcggacaat ttgcagcaac ttttctggtt caaacaaaaa aatcgcggca tcgggcaatt
    23401 taccatcggt gtcaggaata cgtgcaacaa tgccgtcatc acaggcgacc accgacgcgt
    23461 cagcgcccca tagcgcatgt attcgcccgg caatcgccac cgcccagggt tcatgcaccc
    23521 gtcttccata gggagagtgc aaaataatac gccagtcacc aatttcatca cggcaccgtt
    23581 cgaggaccag atggcgactc cccggaacga tgcccgtcgc gttgcgctgc tcctcaatca
    23641 acccctgaat attggcgatc gtattttctt ctgccagcca cgggggaata gtcccggaaa
    23701 agaacgcgcc atccgccagc aaatgaagaa aatcgccgat catctcgcct aattcagccg
    23761 gacgtccgtt accttcacca cgccagaagg ggagccgggc agaacgaccc ggagcaggag
    23821 tcacaatcac ctgatcgcgg gtgatttgct ggatccgcca tgaggtagcg ccgagagtga
    23881 taatgtcgtt cacccgcgac tcatatacca tctcctcatc cagttcaccc acccgccgcg
    23941 aaccggcctt ttcttcacct tcgggtaata acacgctata catgccacga tccggaatgg
    24001 tgccgccgct ggtaaccgcc aacaattgag cgccaggtcg ggcggtcaat atcccggtct
    24061 ccctgttcca gaccagtttg gggcgaaaag cagaaaaatc gccagaggga tagcgcccgg
    24121 aaagcatatc cagcgtggcg tcaaaaacac gtcttggcag atctttccac ggtgcggcac
    24181 ggcgtacgcg ggagtaccat tcgtctacct gtaatgcatc catcgccgcg gcggcaacgg
    24241 tttgctgcgc aaggacgtcg agaggattat gcggtggtgt caggttttcc agcctgcctg
    24301 cgaacataca ctctacaatg actgcggaat cgactaaatc acgccgggta cgggggaaaa
    24361 acagcccttt agatacaccg ccaacctgat gtccggcgcg accaatgcgt tgtaacccac
    24421 tggcaacaga aagcggcgtt gccacctgaa tcaccagatc caccgcgccc atatcaatcc
    24481 ccagttcaag actggaggtt gcgaccacgc agcgtaattc acccgatttc agcgcctgtt
    24541 cggtgattgc tcgttgttct ttagagacgg agccgtggtg tgagcgggca ataaaaacgt
    24601 cgctactttg tacacggtta gaggttgcgc cggaggtcga ctcgaaatgg gccgcatcaa
    24661 cggcgataga cggggaacgc tgtaagcgtg cggcgtaaag ctcatttaat cgtgccgtca
    24721 gtttttccgc cagcccccgc gaattagtaa agacaatggt cgagcgatgg cgcaacactt
    24781 catcaaggat acccgtttca atatatggcc agatggagcc ttcccggccg gcatggctgt
    24841 cttcgccggt gccgctggcg accgatgaga catcatccat attggcgacc ggtacgacaa
    24901 ttcgtatctg cggatggcgc attgcgggcg ggttgactac cgtaaccggg cgatcgccac
    24961 caagaaatgc tgccacatcg ctggctgagc gcacagtggc agaaaggcca attcgctgtg
    25021 ctgaggtgtg gagcagcgca tcgagccgct ccagacttaa cgccagatgc gcaccacgtt
    25081 tactgcccgc taccgcgtgg acttcatcaa taattaccgt ttcgacgccg cgtagcgttt
    25141 cgcgcgcgcg ggaggtcagc atcagataga gtgattcggg tgtggtgatc agaatatccg
    25201 gcggattacg ggtgagtttg ctgcgttcct gtgcaggcgt atcgccagta cggatcccta
    25261 cgcgaagatt gacttccgtt tcgccgcgcc gccgccgttc atcggcaata cccttcaacg
    25321 ggatctgcaa gttgcgctga acgtcggtgc ccagggcttt tatcggtgaa atatagagga
    25381 tgcgtgaggt tttacgctta tgcgcctcgc gggtatcttc gccgccttcg cggaagagcc
    25441 gatcgagggc gtagagaaat gctgccagcg ttttcccgga gccggtcggt gcaatcacca
    25501 gcgcatgttc gcttcgcgcc gccacatgcc aggtttgcgg ctggacagcg gtcggctgtt
    25561 taaaggcgcg aagaaaccag tcgcgggtcg ccggtgaaaa cacgtccggc aggagcgatg
    25621 aagggtctgg attatctgcc attaacgcta ttccccgtga atatcatgca ggatgcgtgg
    25681 aatagcctca ctatagatgc ctgaatcatt gcatgtcatc aggcatcgac tcgattacac
    25741 ctcttcggcg gcagatagcg gccagcctcc cagacgtttc cagcggttga cgatttcaca
    25801 aaacagcaca gcagtgcgtt cggtgtcgta cagcgcggag tgcgcctggg tgctgtcgaa
    25861 gtccatgcca gcggtctggc aagcctttga caatacggtt tgtccgagtg ccagcccggc
    25921 cagtgcagca gtgtcaaaag tggcgaaagg gtggaacggg ttacgtttca gtgaggcgcg
    25981 ttctgcggcg gccatcataa agctgtgatc aaaattggca ttgtgcgcca ccataatggc
    26041 gcggttacag ccgctcgctt taataccttt acgtacaact ttaaaaattt cgtgcagcgc
    26101 ctcgtattcg ctgaccgcgc cgcgatcggg atcgttcggg tcaatgccgt tgaaggcgag
    26161 ggcttctggt tgcaaatttg cgccgacaaa tggttcgacg tggaaatgta atgtggtgtc
    26221 cggcatcagc cagccttgtt catccatttt cagggtgatg gcggcaatct caagcagcgc
    26281 atcggttttg gcgttaaatc cggctgtttc aacatcgatc acaacaggat aaaaaccacg
    26341 aaaacggtcg cacagaccgg taagttgagc gttatcggac atctgattct cttaatacgg
    26401 ataaattgca gcgcgcatta tgacaaatat tacttgtcga tgcagtaaag atgcgggcgc
    26461 gatgagttca cgcccggcag gagattagtt gcccagaccg cgaccggcgt ctttctcttc
    26521 gattaactca attttgtaac cgtccggatc ttccacaaac gcgataaccg tagtaccgcc
    26581 ttttaccgga cccgcttcac gggtcacgtt acccccgttt tgacggattt tttcgcacgc
    26641 ttcagcggcg ttatctacgc taagcgcgat gtgaccataa gcagtgccga gttcgtattt
    26701 atccacgccc cagttgtagg tcagttcaat caccgcttct tcggtttccg ggccgtagcc
    26761 aacaaacgcc agtgagtatt tgtattccgg gttttcgctg gtacgcagca gtttcatgcc
    26821 cagcactttg gtataaaaat cgatggagcg ttgcaaatcg ccaacgcgca gcatggtatg
    26881 aagaagacgc atctttttat cctcaaaatg gctaacagat tcaaaatgtt gttttagtat
    26941 agcggcggct ttacgccgct cgcaatgttg gattacaacg tcgggtaatc ggtatagcct
    27001 tccgcgccgc caccgtagaa actttcggca cgctgtgggt taagctcagc tttgcgctgc
    27061 aagcgggcga ccagatccgg gttcgcaatc cagtcacgac caaatgccac cgcatcaatt
    27121 aaccctttgc cgatcagcgt ttcagctttt tctactgtgt atgcacctgc gccgataatc
    27181 ggaccgtgga aacgggcgcg tactttttcg cggaacgcat cagtatacgg ttcacccccc
    27241 gcccaatctg gttctgacat atgcagataa gcaatgccgc gtttacccag ttgttcaatc
    27301 agatacagtg catcggcttc ttcattcggg ccgttatctg tgttctggaa agtaccgatt
    27361 ggtgaaacgc gaatgccaat gcgatcggca ccccattctt caatcccggc atcgaccact
    27421 tccagtacca aacgtgcgcg attttccacg ctgccgccgt actgatcggt acgatggttt
    27481 gaagaaggag aaaggaactg atgcagcaaa taaccgtgag cagagtggag ctctaccaga
    27541 tcaaaaccgg cttcacgcgc gttagcaatg gcctgacgga aatcattgac gatacctgga
    27601 atctcttcca gttcaagcgc acgcggcatg gatgtttcaa cacggatcgc ctgaccattt
    27661 tcatcgcgta gagaagtacg tgttcccgcg ctaagtgctg aaggcgctac cggtgcctga
    27721 ccgccaggtt gcaggctggc gtgagaaatg cgtccggtgt gccacagctg cacggccata
    27781 tgaccatttt cagcatgaac gccagcggtg atttttttcc atgcggcaat ttgctccgga
    27841 ctatggatgc caggcgcacc tgcatatcct tttgcctggg cagaaatttg cgtggcttca
    27901 ctaataatca aaccggcact ggcacgttgg cgatagtatt ccgccatcaa cggggtagga
    27961 atgtcacccg gttcaatact gcgcagacgc gtcagcggtg ccataaaaat acggtttgcc
    28021 gccgtgatcg cgcccacttt cagtggggaa tacagttttt cagatgacat aaaggctccc
    28081 ggtcgtctgg tgataaaaaa tgcctgctaa acggcaggcg tcgcaataat gttttttaca
    28141 tgggccagcg cgttttccag tggctcgaaa ctgcgcgaaa ttttggcctg cagattcgcg
    28201 ccaagccaca gtgcgtaaag cacttgtgcc tgttgcagcg gttcgccaca aaaggttaaa
    28261 caatggttct cacggccatt ttccagcgcc tgagagagca gggcgatcac gccgcgagca
    28321 cctttatcca tcgcgctgcg catatcttct gacagatcgc acacttcggc agagagtttt
    28381 actgtcaggc aaccactgat ggttccatgt tggcaaaact ggttcagtgt ttgctggtaa
    28441 taagccagta tgcggtcgcg gtagttacct tcgccggatt gcagcaactc agtcagtcgc
    28501 tggtgatatg cggcgtaatg acgctcaagc atggcaacgc caaacgcttc tttagagcga
    28561 aagtagtgat agaaggaccc tttcggcact tcagcggttt ttagtaattc gcttagcccc
    28621 atcccggtga atccacgttg caggcaaagt tgctcgcccg tcgccaggag atgttcgcga
    28681 gtatcatgtt cggtgtgttt gttcatgcgt tggagtgtag tagaccagtc ggtctagtgc
    28741 aagcaaagtt gctactttgg acattaacag cttcaataat ggtaataatc ttatctgagg
    28801 agggcgaagt ggcggagcaa ttagagttct ttcccgtcca gagcccgtgc cggggaattt
    28861 gccagtctga cgaacgcggg ttttgtcgcg gctgttttcg tagtcgtgat gagcgtttta
    28921 actggaataa aatgagcgat ggcgaaaaac aagaggtgct gcgcctttgt cggcagcgat
    28981 taatgcgcaa attacgcgca aataagccag cgtcatcaga cgaaccggag caaccatcac
    29041 tcttttgaac ctaatcttgc gtatactcct ctcatatctg ataagaggaa gcgattatgg
    29101 ttcagcgtat tactattgcg ccgcaaggcc cggagttttc ccgttttgtg atgggctact
    29161 ggcgattgat ggactggaat atgtccgccc gccagctggt cagttttatt gaagagcatc
    29221 tggatctcgg cgtgaccacc gtggaccatg ctgatattta tggtggctat cagtgcgaag
    29281 cggcgtttgg cgaggcactg aaactggcac ctcacctgcg tgaacggatg gaaatcgtca
    29341 gtaaatgcgg tatcgcgacg accgcgcgtg aagaaaacgt cattggtcat tacatcactg
    29401 accgcgatca catcattaag agcgccgaac agtcgctaat taatctcgcg accgatcatc
    29461 tggatttgct gttaatccac cgaccagacc cgttaatgga tgccgatgaa gtggcggacg
    29521 cgttcaaaca tctgcatcag agcggcaaag tgcgtcattt tggcgtatcg aactttacgc
    29581 ctgcgcaatt tgccctgttg caatcacgtc tgccgtttac ccttgccact aatcaggtgg
    29641 aaatatcccc ggtgcatcag ccgttactgc tggatggcac gctcgaccaa ctacaacaac
    29701 tgcgtgttcg tccgatggcg tggtcctgcc ttggtggtgg tcgtctgttt aatgatgatt
    29761 atttccagcc gctgcgtgat gaactggctg tggtggcaga ggagttaaac gcgggctcga
    29821 ttgaacaggt ggtttacgcc tgggtattac gtttaccatc gcagccgctg ccaattatcg
    29881 gttcaggtaa aattgagcgc gtacgggcag ctgtcgaagc agaaacactg aaaatgaccc
    29941 gtcaacaatg gtttcgtatc cgtaaagcgg cactggggta cgacgtaccg taagcacttt
    30001 taggaatagc cgccgttcaa aaatgtgtca ctggtttaca cttattcagg aatgcacaat
    30061 gaacggaggt cctatgaaac gttttagtct ggctattctg gcgctggttg ttgcaaccgg
    30121 cgcacaagct gccagtgaaa aagtcgagat gaacctcgtc acgtcgcaag gggtagggca
    30181 gtcaattggt agcgtcacca ttactgaaac cgataaaggt ctggagtttt cgcccgatct
    30241 gaaagcatta ccccccggtg aacatggctt ccatattcat gccaaaggaa gctgccagcc
    30301 agccaccaaa gatggcaaag ccagcgccgc ggaatccgca ggcgggcatc ttgatccaca
    30361 aaataccggt aaacatgaag ggccagaagg tgccgggcat ttaggcgatc tgcctgcact
    30421 ggtcgtcaat aatgacggca aagctaccga tgccgtcatc gcgcctcgtc tgaaatcact
    30481 ggatgaaatc aaagacaaag cgctgatggt ccacgttggc ggcgataata tgtccgatca
    30541 acctaaaccg ctgggcggtg gcggtgaacg ctatgcctgt ggtgtaatta agtaattaag
    30601 aggccagcgt accttgcggt ggtgcttgct caagttgcga aagcgagcag tacagccgcc
    30661 agacaattgc cgccagctca cgggcggcag gttgatgatg acgggcaagg ctgtcgcaaa
    30721 tccgctgtaa ttcttcaagt gtggccgcca gtgatttttg ctgaacgcca cgctcactca
    30781 tcactccccg caacagtgaa atacagttat cccgtactcg cgataacgga tcggaacgcg
    30841 attcccagtc gcgcaattgc cagacaacat gagaacagtt cagcagcact acaccccagc
    30901 gtaataacca acggcgagcc agcgcatcct ggctgttact caactgactg acgtgatgat
    30961 aagtgagcga ttcaaattcg ctttcactca gtgttggatg gcggcttagc tgatcgacaa
    31021 aatcccggcg cagcgcgcga atatggcggc ggcttttacg agcatccgat cctggacgca
    31081 gaatggcgaa cgctaaccac gccaacgcga cgccaacgat ttttgccaga ttatcgttaa
    31141 gaaaatcagc aaaatcatac accgggggat tagtgacagc gataaaagaa cccataaaaa
    31201 caatcagttg cccccacaat gcggcaaatt ttggcatctg caatttaaga agctgcattg
    31261 tcgccagcag tggaaagaga aacagtaaaa attgccacag atcgctaatc tggaccatca
    31321 gaccaaattt gaccacaaag ctgaatagcg aaagtaacac cagcgtgcgc atcagaagtg
    31381 acaacgactt aaacggtgct gcgacggcgg agtagagtac gcagctaatt gctgccagcg
    31441 ttaatgcatt ggcaccggca tcccattgcg aagcaatact ccatgcgcca atcatcatca
    31501 acgtacaaaa tgtacgcagc ccgctccaca tagcttcggc gttatcggta tgacgagcca
    31561 ggccggatgt ccgtgggagt ctggtatgat catctacacc gctttgcaga cgatgtaatt
    31621 cctgactact ttgcagataa aggcggcaaa aataacgtag tcgctgccag aaggcgacgt
    31681 gccgatagtc ggcgacgttg gtcgggcgta gcggggcgat aatacgtgcg acggtgtaaa
    31741 catctgtttg cgaactggcg agcgccgtca gcaactgttc gagaatttct cgtgtggcac
    31801 ctggcggtga gggccagttg agcaacatac gtcgcaggct ggagatgaca ctggtcatac
    31861 gtaattgctg gtggagcagc gcattaaggc gcgcgttttg ctggcgaaaa cgatagtggc
    31921 tccagaaagc ctggatacgc agcaaattca tggtcagtat ctgcccaatc accccttcat
    31981 gtgctgcacg aatggcatcg gttgtttcag gctgccagag taaactggca tgttccagta
    32041 atcgggcgtg catgtttttc aatgcggtta aaagggcagt agcatcggaa ctgctcggca
    32101 ggatcatcat catcatgccg ccgcacaaaa taccgactat tacctcgcaa acgcgcgcct
    32161 gagcgatatc ccacagctgg ctggcctcag taatattaac catcggaaag gcgatgatgg
    32221 cagccgtgta gcccgccagt tgaaatgcat acgcgacgtt attcgtgaag tgcgcacagg
    32281 cccaggtaca aaagccaagc cacgccgaca tgctcaatag aaaaaaccac ggctcattga
    32341 gcgtatgccc ggcaagaagc agtgccgcaa tggctccgag caaactgcca gcgatgcgtc
    32401 cgaggctttt gctgataaca ccgccaacgg tgggaaagct aaccactgca gccgaggtca
    32461 tcgcccaata gggttcatcc agatttaaat aataggcaac cgtcagcgcc agacacatgg
    32521 caatggtatt gcgtaacgca taacgccatt gcgccagcgt ggccctgaac cagggcaaat
    32581 tgcgcaagga ccatgacgat gcgttcatta ttgacctacg gcaatgctac aggtggtgcc
    32641 cgacaccaac gtgacatcgc ctgggacttt atccagcgca aagcggacgg gaacgcgttg
    32701 ggcgagtcga acccagggga cgttaggttt aacatccgga ataaggcttg agtcactttc
    32761 aacgctctga tcataaatcg cccgaccgat actggaaacg tgaccctgta acgttttgtt
    32821 atcactatag agggtaattt gtgctggtgc accttcgcgg atatggcgca acttggtttc
    32881 ttcaaaataa ccaatgacgt aaaacgagtg gctgtcgaca agggcaaaca gcggtttccc
    32941 ggtatcagcg taatcgccga tgcgggtagt aaggttagtc acccatccac tcaccggggc
    33001 gcgaatttcc gtttgcgcca gttgccattg tgcctgtttc agcgtcgcct gtgcggcatc
    33061 aacactggcc tgcatcgctt taacattgag gttagcggta tcgagttctt cggcagaaat
    33121 aaaattttgt gagagatgac gacgacgatt cgcttcgtta ttggcttttg cgaggtcaga
    33181 ttgcgctttc gccagctgag cctgtgcgtt cagctcggcg atctgaaagg gcgttttatc
    33241 gatcgtgagc agaagatccc ccgcgttaac cagctggttg tcttttatat tcagctcaac
    33301 aatacgtccc gacacctgtg gggtgataga aacctgttct gcgcgtattt tcccgtcgcg
    33361 tgtccacgga gattgcatgt aataattcca cagccaccat ccggcaagaa ccgcaactac
    33421 cgctacaatg attgttgaga aatacttaat tgttttaatt gacatagtta ccacgcaatc
    33481 agtattgcca gagcaaggca aacgcaaatc gcaaacagcg ataaatccat taacaaggga
    33541 tgccagatgt caccggcgta gatccagcca cgaagcaggc ggtgtacgac aagccagatg
    33601 acgaatccaa acgcgaatgc tttgaaaaac ggaggaaagt agacggacgc accgaacacc
    33661 agatcttgta agggcaatcc tgttgcattg agcataaact tcacaaagta gattccttta
    33721 cgaccgaata tattgcgtta gattaataaa tattctttaa gtgcgaaaaa tttacgcgca
    33781 atttctgaaa aatatgtctg acggtaacca aatgcagcaa tacatttgtt ttagcaatac
    33841 aattgctgca cactattcta aaagccgcat aatatcttag caagctaatt ataaggagat
    33901 gaaattggaa tcgccactag gttctgatct ggcacggttg gtgcgcatat ggcgtgctct
    33961 gatagaccat cgcctgaaac cgctggagtt aacacaaacc cattgggtta cgttacacaa
    34021 tatccatcag ttacctccag accagtcgca aattcaactg gcaaaagcga ttggcatcga
    34081 gcagccatca ctggtccgta ctctggacca actggaagaa aaagggttaa tttcgcgtca
    34141 aacttgtgcc agcgatcgtc gggctaaacg tattaaactg acggaaaagg cagagccgct
    34201 gatcagcgaa atggaagctg ttattaacaa aacccgcgcg gaaatattac atggcatctc
    34261 cgcagaggaa ctggagcaac tgattacgct catcgcaaaa cttgagcata atatcattga
    34321 gttacaggcc aaagggtgaa atgaaggggg cgtgtggtca gtaacctgac cacacgcaaa
    34381 cttatttagc gcggagaaac ggtcacctga ctgccattgc tggccagtac gacacgttgg
    34441 cccggagaga aacgagtgtt gccttgtttc tgtaccacca tgatggtatt accatcgtct
    34501 ttacgaattt ccagctcgac accctgcgtt ttgttcattg cactctgtac gccctgacca
    34561 gctacgccac ctgcaacagc gcctgctgca gtagccagag aacgcccggt tccgccacca
    34621 acagtattcc ccaggaaacc accaagaaca gcaccgccaa ttgcaccgat aacgttggaa
    34681 tcatcaccgc cctgaatctg taccggacgt acgttaacga tggtgccata gctgacattc
    34741 tgtacttgtt tcgcttcaga agcggtataa acatcccctg acagggtgtc gttattaaca
    34801 caaccgacaa gagacagacc taccattgaa acaaccaata cgcgtttaat cattgaaaaa
    34861 tctcctgttc accatgaaac gccacgcaag catccctcat ggtcaaagta tatggcatat
    34921 gtgaatccat ggttacatgt tctaccaaat atgagcaaat cataatgaaa gtaggatcaa
    34981 ccaattataa acaaaacatt catgatgatt attgatttga agataatgtt ttactaccaa
    35041 cggtaaaaat cggtcattcc gcatggtatt cacgaaaagt ttatgtttga gtggtgcgca
    35101 aacgtcagat tgaaaaagga tgaactatga aatcgggccg ctttattggc gttatgtcag
    35161 gcaccagcct tgatggtgtt gatgttgtgt tggcgacaat tgatgaacac cgggtcgcac
    35221 agctggcaag tttgagttgg ccgatcccgg tatctctgaa acaggctgta ctggatattt
    35281 gccagggcca gcagcttaca ctttcgcagt ttggacagct tgatactcaa ctcgggcgac
    35341 tttttgctga tgcggtcaat gccttgctta aggaacaaaa tctgcaggca agagatatag
    35401 ttgcgatcgg ttgtcacggt caaaccgtct ggcatgaacc gacgggcgtg gcaccacaca
    35461 ctttacagat tggcgataac aatcaaattg tggcacgcac cggaattacg gttgtcggtg
    35521 attttcgccg tcgcgatatt gccttgggag gacaaggcgc accgctggta cctgcgttcc
    35581 atcatgcgct gctggctcac ccaaccgagc gacgaatggt gctcaatatt ggcggcatcg
    35641 ccaatctgtc actgctcatt cctgggcagc cggttggggg ctacgatacc ggtcctggta
    35701 acatgctgat ggatgcctgg atctggcgtc aggccggtaa accttacgat aaagatgccg
    35761 agtgggcacg ggcgggtaaa gttattctcc cactgctgca aaatatgctc agcgacccgt
    35821 atttctcgca acctgcaccg aaaagcaccg gacgcgaata ctttaactat ggttggctgg
    35881 agcgccattt gcgccatttt ccgggtgttg atccccgaga tgtgcaggcg acactggcag
    35941 aactcaccgc cgtgaccatt tctgaacaag ttttgttgag cggtggctgc gaacgattga
    36001 tggtatgtgg tggaggtagt cgtaatccgc tactcatggc gcgtctggcg gcattactgc
    36061 caggcacaga agtcaccacc accgatgccg ttggcattag tggcgatgac atggaagcat
    36121 tggctttcgc ctggcttgcc tggcggacgc tggcgggatt accaggaaat ctgccttccg
    36181 tcactggcgc aagccaggag acggtactgg gggctatttt ccccgctaac ccgtgatatc
    36241 agagttaact gaatttttct taccgcgtct gccgttacac ttggaacgtt agggagggcg
    36301 tattgccctc cagaccagga aagtcttcgg gatatgacta tgaaaaaact gttaattatc
    36361 attttgccgg tccttctctc cggctgtagc gcctttaatc agctggttga gcgcatgcaa
    36421 accgatacgc tggaatacca gtgtgatgaa aaaccgttga cggtcaaact gaataatccg
    36481 cgccaggagg tcagttttgt ttacgataat caactactgc atctcaaaca gggcatttca
    36541 gcctctggcg cgcgttacac tgacggaatc tatgttttct ggtcgaaagg cgatgaagcg
    36601 actgtctata aacgcgaccg catcgtcttg aataactgtc agttacaaaa tccacagcgt
    36661 tgagattttt ccaggggcgg cgcacaatag cgtcacccac tgacaatccg taaagaaaac
    36721 catgtctgat aacgacgaat tgcagcaaat cgcgcatctg cgccgtgaat acaccaaagg
    36781 cgggttacgc cgccgcgatc ttcccgccga tccattaacc ctttttgaac gttggctctc
    36841 tcaggcttgt gaagccaaac tggcggaccc taccgcgatg gtggtcgcta ccgtggatga
    36901 acatggtcag ccttatcagc gcatcgtttt actcaaacat tacgacgaaa aaggcatggt
    36961 gttttacacc aacctcggca gccgtaaagc acatcaaatc gaaaataatc cgcgcgttag
    37021 cctgctgttc ccgtggcata cccttgagcg ccaggtgatg gtgatcggta aagcagaacg
    37081 actttcgact ctcgaagtga tgaaatattt tcatagccgc ccgcgtgata gccagattgg
    37141 tgcatgggtt tcgaagcagt ccagtcgcat ttctgcccgc ggtatccttg aaagtaaatt
    37201 cctggagctg aagcagaagt ttcaacaggg cgaagtgcca ttgccgagct tttggggcgg
    37261 ttttcgcgtc agccttgaac agattgagtt ctggcagggt ggtgagcatc gcctgcatga
    37321 ccgctttttg taccagcgtg aaaatgatgc gtggaagatt gatcgtcttg caccctgaaa
    37381 agatgcaaaa atcttgcttt aatcgctggt actcctgatt ctggcacttt attctatgtc
    37441 tctttcgcat ctggcgaaaa gtcgtgtacc ggcaaaggtg cagtcgttat atacatggag
    37501 attttgatgg caagcagtaa cttgattaaa caattgcaag agcgggggct ggtagcccag
    37561 gtgacggacg aggaagcgtt agcagagcga ctggcgcaag gcccgatcgc gctctattgc
    37621 ggcttcgatc ctaccgctga cagcttgcat ttggggcatc ttgttccatt gttatgcctg
    37681 aaacgcttcc agcaggcggg ccacaagccg gttgcgctgg taggcggcgc gacgggtctg
    37741 attggcgacc cgagcttcaa agctgccgag cgtaagctga acaccgaaga aactgttcag
    37801 gagtgggtgg acaaaatccg taagcaggtt gccccgttcc tcgatttcga ctgtggagaa
    37861 aactctgcta tcgcggcgaa caactatgac tggttcggca atatgaatgt gctgaccttc
    37921 ctgcgcgata ttggcaaaca cttctccgtt aaccagatga tcaacaaaga agcggttaag
    37981 cagcgtctca accgtgaaga tcaggggatt tcgttcactg agttttccta caacctgttg
    38041 cagggttatg acttcgcctg tctgaacaaa cagtacggtg tggtgctgca aattggtggt
    38101 tctgaccagt ggggtaacat cacttctggt atcgacctga cccgtcgtct gcatcagaat
    38161 caggtgtttg gcctgaccgt tccgctgatc actaaagcag atggcaccaa atttggtaaa
    38221 actgaaggcg gcgcagtctg gttggatccg aagaaaacca gcccgtacaa attctaccag
    38281 ttctggatca acactgcgga tgccgacgtt taccgcttcc tgaagttctt cacctttatg
    38341 agcattgaag agatcaacgc cctggaagaa gaagataaaa acagcggtaa agcaccgcgc
    38401 gcccagtatg tactggcgga gcaggtgact cgtctggttc acggtgaaga aggtttacag
    38461 gcggcaaaac gtattaccga atgcctgttc agcggttctt tgagtgcgct gagtgaagcg
    38521 gacttcgaac agctggcgca ggacggcgta ccgatggttg agatggaaaa gggcgcagac
    38581 ctgatgcagg cactggtcga ttctgaactg caaccttccc gtggtcaggc acgtaaaact
    38641 atcgcctcca atgccatcac cattaacggt gaaaaacagt ccgatcctga atacttcttt
    38701 aaagaagaag atcgtctgtt tggtcgtttt accttactgc gtcgcggtaa aaagaattac
    38761 tgtctgattt gctggaaata atgcattaag tggaaagggg gagtgagaaa tcactccccc
    38821 tggtttttat acagggaaca tgatgaaaaa tattctcgct atccagtctc acgttgttta
    38881 tggtcatgcg ggtaacagtg cggcagagtt tccgatgcgc cgcctgggcg cgaacgtctg
    38941 gccgctgaac accgttcaat tttctaatca cacccaatac ggcaaatgga ctggctgcgt
    39001 gatgccgccc agccatttaa ccgaaattgt gcaaggcatt gccgccattg ataaattaca
    39061 cacctgtgat gccgtattaa gtggctatct gggatcggcg gagcagggtg aacatatcct
    39121 cggtatcgtc cgtcaggtga aagccgcgaa tccgcaggcg aaatattttt gcgatccggt
    39181 aatgggtcat ccggaaaaag gctgtatcgt tgcaccgggt gtcgcagagt ttcatgtgcg
    39241 gcacggtttg cctgccagcg atatcattgc gccaaatctg gttgagctgg aaatactctg
    39301 tgagcatgcg gtaaataacg tcgaagaagc ggttctggca gcgcgcgaac tcattgcgca
    39361 agggccacaa attgtgttgg ttaaacacct ggcgcgagct ggctacagcc gtgaccgttt
    39421 tgaaatgctg ctggtcaccg ccgatgaagc ctggcatatc agccgtccgc tggtggattt
    39481 tggtatgcgc cagccggtag gtgttggtga tgtgacgagc ggtttactgc tggtgaaact
    39541 gcttcagggg gcaacgctgc aggaggcgct ggaacatgtg accgctgcag tctacgaaat
    39601 catggtgacc accaaagcaa tgcaggaata tgagctgcaa gtggtggctg ctcaggatcg
    39661 tattgccaaa ccagaacatt acttcagcgc aacaaagctc tgaaatatct catttcggcc
    39721 cacaacgacc tgtgggccga tggctattac tttaagcctt ccgctgacag cgcgtcttgt
    39781 acttccggac gttcagccat acgttgcata aatgctgcaa tgtgctctaa cccttccaga
    39841 ttcagtttca ccgcgtatgc ccagcgcaga accgtaaaca gataggcatc agcaattgta
    39901 aatctttgcc cgcagatcca gtgctcatcc ttcagtgcct cgttcacata ttgcagcttc
    39961 ttctccagct gcgcgcgaac tgtcggtttg tactcttccg gtgtatcagg gcgaaacaga
    40021 ggtgtgaaac ctttatgcag ctcggtggcg atgtaattca gccattcgat ggttttatag
    40081 cgggaaatac tgtttaccgg tgccagcaac tggcggtcgg ggacgctgtc ggcaagatac
    40141 tgcataatcg ctacgccttc cgtcagcaaa gtaccgtcat ccagcagcaa tgcaggcacc
    40201 tgccccttag ggttaacggc aaagtaatcg tcaccgtttt cgagacgttt tttcattaaa
    40261 tccacactga cgagggtaaa atcctttccg ctctcacgca gggtgatatg ggaagcgaga
    40321 gagcaggcac ccggtttgta gaacaatttc atcggtaact ccttttgtct gtggtttaaa
    40381 gtatggtagt gcgttgctga acaaaaaaaa agccgctaac gaaaagttag cggcttgtaa
    40441 aagagtttcc ctgaatttta cgctacggct gctttcgccg ctttgtctgc agcgtcatcc
    40501 tgcgtcatgc ggtgcagttt cggcgcggtc agcagcatca gtactgcaat aacggcagta
    40561 gcgacaccaa tctgcaagaa tacgcgacca tagacttcca gtgacatcag cggatcggta
    40621 acgttatccg gcacagccat catacccgca acataaccac caatcaggtt tgcaccggca
    40681 gtggtcagga accagctacc cataatgaag cccatcagac gctgcggaac gagttgagca
    40741 accattgcca gacccagacc agagatcatc agttccccga tgctctgcag gccatagctt
    40801 gcgaccagcc agcttacaga cacgatacca gcgtcagacg cgaatttcgc acccagcggc
    40861 agaatcagga acgcaccaga acacatcacc atgccgattg caaacttggt tggcatcggc
    40921 agggtatcgc ccatcttgtt atagatagcg gccagaatcg gactaccgat gatgatccag
    40981 aacgggttca gtgcctgata ctgctcaggt tctacggcca gacccagaat ggagtgctca
    41041 acgttacgaa tcgcaaagaa gttcagtgac gttggcatct ggctgtacag cacgaagaag
    41101 ataatggctt cgagcatcag gatgaaggca acgatcattt tacgacgcgc agcacctttc
    41161 atcgcgaagg cttctttacc gaagataacc acgataccga aggcaacaac gcccagcgcc
    41221 atacgcgcaa cttcctgatt gtgcagcagc caggtggcga tagcgatcag tgccacaaca
    41281 ccaataatgg tcagcagcag gttacggtag ttgataggct cgaagtctgg ttttgaaccg
    41341 tactgtttaa cccagcgttg gcagaaggcg aagttaacga tagtgatcag caggcctaca
    41401 acgctcaacg caaacgcaac actccagccg tatttcgcgg ccagccacgg cgtagcaatc
    41461 atagagaaga aagagccgat gttgacggac atgtagtaca tggtgaatgc accgtccaga
    41521 cgcgggtcgt ttttctcata gcatgtagaa agcagagaag acgggttagc tttaaacagg
    41581 ccgttaccga ccgcaatagc cgccataccc atataaacga taccggcgtc gtgaccagac
    41641 caggcaacca gagcataacc aatcgccagc acaatagcgc cgagcataat tacgcgttta
    41701 gtacccagta ccttgtcacc taaccagccg ccgatagcga ccagaccata aaccagggca
    41761 ctaaaggaag agaaaagggt gattgaatcc gcttcagaca tacccagttg tttaaccagg
    41821 taaacagcca taattccttg taggccgtaa taaccaaaac gttcccataa ctcaatcgag
    41881 aagatgagat agaacgcctt cggttgtttg aaagcgttca aactgacgct ttcagttggt
    41941 ttttggtttg cagtggacac ttttacctct ttttttacat cccatattaa cgggggtgct
    42001 ttctcgcgtt atgtataaaa aacatacgcg caattgttat agtgggaggg gaaacggcag
    42061 gtaatgttca ctatcttgca ctttcagaca agtcctttgt aataatctgt tacatataac
    42121 tgaggcgggg aattcaacca ttccgggaaa tgttatccag cgttaaattt ttcaaaaaac
    42181 gtaacggcag attttttcac tgcactgaga ggggggtgat ggcttaacgg cgatatgttc
    42241 tgctatttag cgtttttact agtgagatag tccagtttct gaaaaatagc cagtgtaatg
    42301 ttttgtaggt caatatttgt tgcgtgtgta aatttaaatg attttaacct gattcttgca
    42361 atgtttttac attgcgacag catcgtgatc ttgatcacga atgaatagaa aatttcgcta
    42421 ttaaaaaaac aattaacctg catttttggt tatccgcaaa cggattacct gatgataacg
    42481 ctaagcaatg gcatcattga cgttaaaaag atgttttaaa agaggataaa gaaaggttat
    42541 caatggggta atcggtgtta ccccttttct tcagatgtca actttctctt tgtattcaca
    42601 aagatcttca ataatacaag agccacagcg gggcttgcgg gcaatgcagg tataacgccc
    42661 gtgcaggatc aaccaatggt ggcagtcgac tttaaactct gctggaacca ctttcagtag
    42721 cttttcttct acctgttcga cgtttttccc cggcgcaaat tgagtacgat tacaaacgcg
    42781 gaaaatgtgc gtgtcgacag caatagtcgg ccagccgaat gcagtgttta atacgacgtt
    42841 ggctgtttta cgacctacgc cgggcagggc ttcaagcgca gcacgatctt ccggaacctc
    42901 gccattatgc tgctccagca agatacggca ggttttgatg atattttctg ctttgctgtt
    42961 ataaagccca atcgttttga tataggtttt caccccttca acgcccagtt caagcatcgc
    43021 tgcaggcgta ttcgccaccg ggtagagttt cgccgtcgcc ttattaacac tgacatcggt
    43081 cgcctgagcg gaaagcagta cggcaatcag caattcaaaa ggcgaactga aattaagctc
    43141 ggtggtggga tgaggattgt tctcacgcag gcgagtgagg atctccaggc gttttgcttt
    43201 attcatcaga cattccctgt ttcaccgttt ggcaatgcac gttctgcagc tgcttcagca
    43261 cggcgctttt tcattctttc atcaatcagg tattttcctg ccagcatcag tcccaggcca
    43321 ataaatgcac ctggtggcag catcgccagc aggaaagggg agtcggtgtg gaaaatctcc
    43381 acgcgtaata cttttgccca gctacctaac agcgcatctg caccgtcaaa caatgtgcca
    43441 ttgccgataa tttcgcgtag tgaacccagc acgaacatgg cgcaggttgc gcccatacca
    43501 attgaaaagc cgtccagtgc cgaaagcgcc ggaccttttt tggcggcgaa ggcttcagcg
    43561 cggcccacaa cgatacagtt agtgacaatc agcggaataa aaatccctaa tgattgatac
    43621 aggccaaagg cgtaggcgtt gatcagcatc tgtacagcgc tgaccaccga ggcgatgatc
    43681 atcacgtaaa tgggaatgcg gatctcggct ggcgtccagt gacgcagcgt cgaaatggtc
    43741 aggttggtca gcgtcagtac cagcgtagtc gcaagtccta aacccagagc gttagtggca
    43801 gtggacgtga ccgccaacag aggacaaagg ccgagcaact ggaccagcgc agagttgttt
    43861 ttccacaacc cctgaacaat aacgtcttta atttcgctca cgctttattc tccacaggca
    43921 ggaagttgag aaagttgtgc cggtaacgtc tgagcgtaca atccggcgcg ttttaccgca
    43981 ttaaccaccg cgcggggagt aatcgtcgcg ccggtgaact ggtcgaaatc accaccatct
    44041 ttcttcaccg cccagtgcgc atcatctgca ccactgattt ttttacccgc aaaatgggtg
    44101 atccagtcag aaaggcgcag ttcgatttta tcgccaagcc ctggcgtttc gtggtgctct
    44161 gtcacgcgcg tgccaagtac cgtgccgtta aaatcggctc ccaccagcag ctgaatcgca
    44221 ccggaatagc catctggcgc ggttgcttcc agaacggcgg ctaccggttt gtcatcctgt
    44281 ttggcgatgt aaacccgatg ctcaccttta cctaactctg gcgcagttac cagatagcaa
    44341 ctctgtgcca gcgcattgtt atagcgttcg gctggcagca cctgatcaaa taacgccttt
    44401 tgttgcagac tggcctgttc agcaatcgtc gttttggtca tctggttgat ggccgcagtt
    44461 aaccctgttg aacccgctgc aaatagcgcc aacgtaatgc cgtgttttcg gatagttttc
    44521 agcatggttt accctttgcg atggccgtag acgcgcggac gcgtgtagta atcgatcaga
    44581 ggaaccgtga tgttcgccag caggacggca aaagccacgc cgtcaggata gccgccgaaa
    44641 ctgcggatca accagactaa taagcccgca agcgcgccga aaataagacg accacgattg
    44701 gtcgtagaag cggtaaccgg gtcagtcaaa ataaagaatg cgccgagcat ggtcgctcca
    44761 gacagcagat gaatttgcgg tgctgccagt gtttctggtg agaacaacca gcccaacatt
    44821 gcgcataacg ccagcgttac taagaagctg aggggaatat gccagcgaat cgctttctgc
    44881 catagcaacc atacgccgcc agccagccag gcgagattta cccattgcca accagcgccc
    44941 gccagaatac cgctgtagat cggatattgc ataatctgtt caaccgaatg accggcacgg
    45001 acagaggttt taaatgtatc cagcggtgtc gcctgactaa tgccatcaat acctaagcgt
    45061 agtgtgttca tatcaccacc actggcggta tgaccgctaa aaataacctg gatggcgtcg
    45121 ataaaaccag ggatgttgac cgcaatttca tgtggcggta accagctggt catctgcacg
    45181 gggaaggaga tcagtaagac cacataacca atcattgccg gattaaacgg gttttgtccc
    45241 agaccgccat acaactgttt agcgatgatc accgcaaaca ccgtacccag cacgaccatc
    45301 caccatggcg cgaggggggg aatacttacc gccagcaata agcctgtcag caatgctgag
    45361 ttatctttca acgttgcggc taccgactgc ttgcgtagtt tgagtacgag agcttcggct
    45421 aacagagcac taaccgatgc caacaggatc tgaacgagag taccccaacc aaaaaaccac
    45481 agttgcgctg cgattcctgg cacggctgcg agcaacacca acagcataat gcgcgatgtc
    45541 tggcgctggt tatgggtata aggggagcta gctattctga ataccattta gtcctcgttt
    45601 acaaccttct gctgggcggc ttttttggcc tgagcgcggg caatagccgc ggcaactgcc
    45661 gctttgcgcg gatcaacctg ttcttctggt accgcattag cctgttgctg ttccagcttg
    45721 cgtgctttgg cgcgtgcaat agccgcttcg acggcagctt tgcgcggatc aacctgttct
    45781 tctggctccg cattagccgg ttgctgttcc cgtttgcgcg ctttggctcg ggcaatagcg
    45841 gcttcgacgg cggctttgcg cggatcgacc tgttgttctg gctcggcatt agcctgttgc
    45901 tgttccagct tgcgtgcttt ggcacgggca atagcggctt cgacggcggc tttgcgcgga
    45961 tcgacctgtt cttctggttc cgcattagcc tgttgctgtt ccagcttgcg cgctttggca
    46021 cgggcaatag cggcttcgac ggcggctttg cgcggatcga cctgttgttc tggttccgca
    46081 ttagcctgtt gctgttccag cttgcgcgct ttggcgcggg cgatagctgc ttcaacggca
    46141 gttttacgtg gatcagcaac ggttgctgcg tcgttagttt gctgcagttc tgcctgtttc
    46201 gctctggctt gcgctttacg ggcttcccgt gctgcaataa ttgcactgtt atccgggcgt
    46261 tcgcccgctt taatcacaat aggctgtgta gcctgggcct gtttctcttt cacccgcgcc
    46321 agagcggcag caatcgcatc tttatctttg gctgcaggtt gaacggctgc gctcttatgt
    46381 cgttcaaggc gagccgcttt ttcgcgctcc agacgagcct ggcgcgcttc gaaacgcgct
    46441 ttggcttctg cggcgcgctt ttcttcctga cgaatagccg caatttcagc tttttcctga
    46501 cggaaatatt gcaccagggg aatattgctc gggcaaaccc acgcgcaagc cccacattca
    46561 atgcaatcag caatgttatg cgtggtagct ttatcgtgtt gctgaccttt gctgaaccag
    46621 tacaactgtt gcggcaaaag atccgcaggg caggcgtcag cacaggcgct acaccggatg
    46681 cagctttgtt cttcctgtgg ttcgccaagt tcattggcag agggagccaa cagacagttg
    46741 gtaatcttta cgaccgggac atccagccat ggcaaggtaa agcccattag cgggccaccc
    46801 ataatcacca tttgatcggc agaggggcag aatccggcat cattcaataa atgacgcact
    46861 ggcgtcccca gccgtgccca gacgttgccc gggcgagcga ttgcttcgcc agtcagggtt
    46921 acaacacgct cggtaatcgg ctcgccatca ataacggcac gtttcactgc ataagcagtg
    46981 ccgacgtttt gcattaatac gccgatatcg gatgaacgcc cgccatgtgg aacctgcttc
    47041 ccggtcagaa tgtaggttaa ttgtttagca ccgccagaag gatatttggt tggaatcacc
    47101 cgcagagaaa tatcgttaga gtccgccagc accgcgcgca gcatggaaat cgcctgcggt
    47161 ttgttatctt caatgccgat aagaatttcg cgtggctgca gaatatgcgc aagaatgcga
    47221 ataccctcta cgacctgagc cgcgcaatcc tgcatcaaac ggtcatcggc ggtaatgtac
    47281 ggctcgcact cagccgcgtt gataatcaac gtttcaatct tatctccgcc accctgcaat
    47341 ttaacgcctg tcgggaatcc tgcaccgccc agcccggcaa caccaaactg atgtatgcgc
    47401 tcgattaact cttcgcgact gcgagtgcga taatcggccc agccgtcgcg cgggatccag
    47461 cagtcttcac catcggcatc aataatcacg cttaattcag ctaaagctga aggatgagcc
    47521 gtagagtggg gcgcaatagc cgtaacggta cccgaggtgg gcgcgtgaac aggcagcatt
    47581 ttgccgcgac cacgggtaag cggctggccg cgcaatactt tatcgccgac gctaacgcac
    47641 aactcacctt cagcgccaat atgctgtttc agtggaataa caaaacgctg cgccaggggt
    47701 acctggcgca ggggtgtacc gttggactgg gttttcatct ccggtggatg gatgccgccg
    47761 ttgaaatccc agattttatt ttttctgaat gcagagaata acttaagcat ggtgttccac
    47821 gggaatgata cgcacgggaa tggtgttcag atcccatttc caggagtcag gtgtttctgc
    47881 gaccggttgc aacgagatgc agtgcgtcgg gcacggatca acacataaat tgcagcccgt
    47941 acagagatca ctcattaccg tatgcatggc acgggtagcg ccaacgatgg cgtctaccgg
    48001 acacgcctga atacatttag tgcagccaat acagttattt tcatcaataa ccgccaccat
    48061 ccgcgcaggc gttatctctt gcgcttcgcc atccagcggc tgcggctcga cattaagcaa
    48121 ctcggcaatt tttagcatca cagcttcgcc acctggggcg caacggttga ttttttcacc
    48181 gttacagctg atggcttccg cgtaggggcg acagccggga taaccgcact gaccacactg
    48241 gctctgcggt aagatttcgt caattttctc aacgaccgga tcgtcttcca ccgcaaaacg
    48301 gcgggaggca taacccagaa tggcgccaaa cgccaggccc agcaggctca cggcggcaac
    48361 ggcaatccag atagcattca ttacaacttc accaaaccac taaagcccat aaaggccaga
    48421 gacataagac ctgcggtaat taacgcaatg gcattaccgc gaaaaggtgc cgggacatca
    48481 gccacagcaa ggcgttcgcg gatggcggcg aagagcacca tcaccagcga gaaaccgaca
    48541 gcggcggaaa aaccgtacag cgccgactgc aagaaattgt gcccgagatt gatattcagc
    48601 aacgccacgc cgagcactgc acagttggtg gtgataagcg gcaaaaaaat ccccagcaga
    48661 cggtaaagca ccgggctggt tttgcgcacc accatctcgg tgaactgcac gaccacagca
    48721 atcaccagaa taaatgccag ggtgcgcagg taaatcagat taagtgggat caaaatccac
    48781 gtatcgataa gccaggcgca aatagacgcc agcgtcatca caaacgttgt tgccagcccc
    48841 atgcccatcg cggtttccag ttttttggaa acccccataa acggacagag accgagaaac
    48901 ttgaccagta caaagttatt gaccagtaca gttccgacaa acagtaacag gtagtcagtc
    48961 atttttcggc ctgaaataaa aaagccgcct attatccgtt aatccagagc aggcgacaac
    49021 aggttaactg taaggttatt acggattcac aaacgtcgct tttacccgcg acgagcgttt
    49081 gaaatagggg acgatcaatg cggttgccaa caaagtaaac agcaactggc gaacggctat
    49141 gccatcttcc acgggtgaaa aagcgaatgc ttttactgcc agcaatacgg aaataagcag
    49201 ccagataata tagtgtttag gaacacaacg ccgacgttta aagaaagcga tggtcaacca
    49261 cagtgtgtaa taccacaagg cgatagcggt aataaaagaa acgccccata agatttgtgt
    49321 cgtcagtgct tgtccgccga gcgtttgaaa tgtttgcgga gaagataacg cagcggtata
    49381 cagcaacaac gccagcgtcg tactcaacag agcgactaaa agccaggcca acgggccaag
    49441 caaccagcct ccaatacgtt gtggcgttgt ggtggtcata ggttctccag aatagcgacg
    49501 caaacaggca aatctaattt taggggcgtt attataaggc ttttataacc gatcgctact
    49561 ttctttattg gacatagtgc cagacggact tcggtacctg gccgaggtca aacaaacgcc
    49621 cgccagaaac cagctctgcg cgacggtgat cggcagcacg atacatattg atcagttcct
    49681 gatcgtccgt cagggtgtaa ttaagatggt cgtagagttt ttccagactt tcgagtgaac
    49741 tgattttgcg aaattttaat aagtagtcct gaacagtcat aaaaggtcca taaaa
//
LOCUS       DAPHKZ010000019        49306 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.019, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000019 DAPHKZ010000000
VERSION     DAPHKZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49306
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.019"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            43..4611
                     /gene="sslE"
                     /locus_tag="RH288_001204"
     CDS             43..4611
                     /gene="sslE"
                     /locus_tag="RH288_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein metalloprotease SslE"
                     /protein_id="HDV4030283.1"
                     /translation="MNKKFKYKKSLLAAILSATLLAGCDGGGSGSSSDTPPVDSGTGS
                     LPEVKPDPTPNPEPTPEPTPEPEPTPEPTPDPEPTPEPEPEPVPTKTGYLTLGGSLRV
                     TGDITCNDESSDGFTFTPGDKVTCVAGNNTTIATFDTQSEAARSLRAVEKVSFSLEDA
                     QELAGSDNKKSNALSLVTSMNSCPANTEQVCLEFSSVIESKRFDSLYKQIDLAPEEFK
                     KLVNEEVENNAATDKAPSTHTSPVVPATTPGTKPDLNASFVSANAEQFYQYQPSEIIL
                     SEGRLVDSQGDGVVGVNYYTNSGRGVTGENGEFSFSWGETISFGIDTFELGSVRGNKS
                     TIALTELGDEVRGANIDQLIHRYSKAGQNHTRVVPDEVRKVFAEYPNVINEIINLSLS
                     NGATLGEGEQVVNLPNEFIEQFKTGQAKEIDTAICAKTDGCNEARWFSLTTRNVNDGQ
                     IQGVINKLWGVDTNYKSVSKFHVFHDSTNFYGSTGNARGQAVVNISNAAFPILMARND
                     KNYWLAFGEKRAWDKNELAYITEAPSLVEPENVTRDTATFNLPFISLGQVGEGKLMVI
                     GNPHYNSILRCPNGYSWNGGVNKDGQCTLNSDPDDMKNFMENVLRYLSDDKWKPDAKA
                     SMTVGTNLDTVYFKRHGQVTGNSAAFDFHPDFAGISVEHLSSYGDLDPQEMPLLILNG
                     FEYVTQVGNDPYAIPLRADTSKPKLTQQDVTDLIAYLNKGGSVLIMENVMSNLKEESA
                     SGFVRLLDAAGLSMALNKSVVNNDPQGYPNRVRQQRATGIWVYERYPAVDGALPYTID
                     SKTGEVKWKYQVENKPDDKPKLEVASWLEDVDGKQETRYAFIDEADHKTEDSLKAAKE
                     KIFAAFPGLKECTNPAYHYEVNCLEYRPGTGVPVTGGMYVPQYTQLSLNADTAKAMVQ
                     AADLGTNIQRLYQHELYFRTNGRKGERLSSVDLERLYQNMSVWLWNDTSYRYEEGKND
                     ELGFKTFTEFLNCYANDAYAGGTKCSADLKKSLVDNNMIYGDGSSKAGMMNPSYPLNY
                     MEKPLTRLMLGRSWWDLNIKVDVEKYPGAVSEEGQNVTETISLYSNPTKWFAGNMQST
                     GLWAPAQKEVTIKSNANVPVTVTVALADDLTGREKHEVALNRPPRVTKTYSLDASGTV
                     KFKVPYGGLIYIKGNSSTNESASFTFTGVVKAPFYKDGAWKNDLNSPAPLGELESDAF
                     VYTTPKKNLNASNYTGGLEQFANDLDTFASSMNDFYGRDSEDGKHRMFTYKNLPGHKH
                     RFTNDVQISIGDAHSGYPVMNSSFSPNSTTLPTTPLNDWLIWHEVGHNAAETPLTVPG
                     ATEVANNVLALYMQDRYLGKMNRVADDITVAPEYLEESNNQAWARGGAGDRLLMYAQL
                     KEWAEKNFDIKKWYPDGTPLPEFYSEREGMKGWNLFQLMHRKARGDEVSNDKFGGKNY
                     CAESNGNAADTLMLCASWVAQTDLSEFFKKWNPGANAYQLPGASEMSFEGGVSQSAYN
                     TLASLDLPKPEQGPETINQVTEHKMSAE"
     gene            4809..5618
                     /gene="pppA"
                     /locus_tag="RH288_001205"
     CDS             4809..5618
                     /gene="pppA"
                     /locus_tag="RH288_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417446.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase PppA"
                     /protein_id="HDV4030284.1"
                     /translation="MLFDVFQQYPAAMPVLATVGGLIIGSFLNVVIWRYPIMLRQQMA
                     EFHGEMPSAQSKISLALPRSHCPHCQQTIRVRDNIPLLSWLMLKGRCRDCQAKISKRY
                     PLVELLTALAFLLASLVWPESGWGLAVMILSAWLIAASVIDLDHQWLPDVFTQGVLWT
                     GLIAAWAQQSPLTLQDAVTGVLVGFITFYSLRWIAGIVLRKEALGMGDVLLFAALGGW
                     VGALSLPNVALIASCCGLIYAVITKRGSTTLPFGPCLSLGGIATLYLQALF"
     gene            5684..6094
                     /gene="gspS2"
                     /locus_tag="RH288_001206"
     CDS             5684..6094
                     /gene="gspS2"
                     /locus_tag="RH288_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system pilot lipoprotein
                     GspS-beta"
                     /protein_id="HDV4030285.1"
                     /translation="MSIKQMPGRVLISLLLSVTGLLSGCASHNENASLLAKKQAQNIS
                     QNLPIKSAGYTLVLAQSSGTTLKMTIISEAGTQTTQTPDAFLTSYQRQMCTDPTVKLM
                     LTEGINYSITINDTRTGNQYQRKLDRTTCGIVKA"
     gene            6112..7071
                     /gene="gspC"
                     /locus_tag="RH288_001207"
     CDS             6112..7071
                     /gene="gspC"
                     /locus_tag="RH288_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HDV4030286.1"
                     /translation="MARVVFRDARIYLIQWLTKIRHTLNQRQSLNTDKEHLRKIVRGM
                     FWLMLLIISAKVAHSLWRYFSFSAEYMAVSPSANKPPRADAKTFDKNDVQLISQQNWF
                     GKYQPVATPVKQPEPAPVAETRLNVVLRGIAFGARPGAVIEEGGKQQVYLQGERLGSH
                     NAVIEEINRDHVMLRYQGKIERLSLAEEERSTVAVTRQKAISDEAKQAVAEPAVSAPV
                     EIPTAVRQALAKDPQKIFNYIQLTPVRKEGIVGYAVKPGADRSLFDASGFKEGDIAIA
                     LNQHDFTDPRAMIALMRQLPSMDSIQLTVLRKGARHDISIALR"
     gene            7101..9161
                     /gene="gspD"
                     /locus_tag="RH288_001208"
     CDS             7101..9161
                     /gene="gspD"
                     /locus_tag="RH288_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HDV4030287.1"
                     /translation="MFWRDITLSVWRKKTTCLKTKKRLLPLVLAAALCSSPVWAEEAT
                     FTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRTMTPLNERQYYQLFLNLLEA
                     QGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEMVTKVVPVRNVSVRELAP
                     ILRQMIDSAGSSNVVNYDPSNVIMLTGRASVVERLTEVIQRVDHAGNRTEEVIPLDNA
                     SASEIARVLESLTKNSGENQPATLKSQIVADERTNSVIVSGDPATRDKMRRLIRRLDS
                     EMERSGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSGREIVSIAASKHS
                     NALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGVQWASKDAGLM
                     QFANGTQIPIGTLGAAISQAKPQKGSTVISENGATTINPDTNGDLSTLAQLLSGFSGT
                     AVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTGSTVGSNN
                     SNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTSLDVVFGERKLKTTV
                     LANDGELIVLGGLMDDQAGESVAKVPLLGDIPLIGNLFKSTADKKEKRNLMVFIRPTI
                     LRDGMAADGVSQRKYNYMRAEQIYRDEQGLSLMPHTAQPVLPAQNQALPPEVRAFLNA
                     GRTR"
     gene            9161..10654
                     /gene="gspE"
                     /locus_tag="RH288_001209"
     CDS             9161..10654
                     /gene="gspE"
                     /locus_tag="RH288_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HDV4030288.1"
                     /translation="MVPVAQETTANTVRLPYSFSRRFSLVAWCEASLEILHVHPLSLS
                     VLQELQRGLNAPFTLRQIDEAEFEQRLNAVWQRDSSEARQLMEDLGSAEDFFTLAEEL
                     PETEDLLESDDDAPIIKLINAMLAEAIKEGASDIHIETFEKSLVIRFRVDGTLHEMLR
                     PGRKLASLLVSRIKVMARLDIAEKRVPQDGRIALLLGGRAIDVRVSTMPSAWGERVVL
                     RLLDKNQARLTLERLGLSQQLTAQLRQLLHKPHGIFLVTGPTGSGKSTTLYAGLQELN
                     NHSRNILTVEDPIEYMIEGIGQTQVNTRVGMTFARGLRAILRQDPDVVMVGEIRDTET
                     AEIAVQASLTGHLVLSTLHTNTAVGAITRLQDMGVEPFLLSSSLTGVMAQRLVRTLCP
                     DCRQPAPATDEEKRLLGITDARTVTLYHPQGCPACNHKGFRGRTAIHELIVVDATLRD
                     LIHRQAGELELERYVRQHSAGIRSNGIEKVLAGETSLDEVLRVTMEA"
     gene            10654..11877
                     /gene="gspF"
                     /locus_tag="RH288_001210"
     CDS             10654..11877
                     /gene="gspF"
                     /locus_tag="RH288_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HDV4030289.1"
                     /translation="MALFYYQALERNGRKTKGMIEADSARHARQLLRGKELIPVHIEA
                     RMNTSSGGMLQRRRHAHRRVAAADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHV
                     KSLGMALRSRIQEGYTLSDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQ
                     RQRLKSRLLQAMLYPLVLLVVATGVVTILLTAVVPKIIEQFDHLGHALPVSTRTLIAM
                     SDALQASGVYWLAGLLGLLVLGQRLLKNPAMRLRWDKTLLRLPVIGRVARGLNTARFS
                     RTLSILTASSVPLLEGIQTAAAVSANRYVEQQLLLAADRVREGSSLRAALAELRLFPP
                     MMLYMIASGEQSGELETMLEQAAVNQEREFDTQVGLALGLFEPALVVMMAGVVLFIVI
                     AILEPMLQLNNMVGM"
     gene            11894..12349
                     /gene="gspG"
                     /locus_tag="RH288_001211"
     CDS             11894..12349
                     /gene="gspG"
                     /locus_tag="RH288_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003912123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HDV4030290.1"
                     /translation="MNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKA
                     DRQKAISDIVALENALDMYRLDNGRYPTTEQGLEALIQQPANMADARNYRTGGYIKRL
                     PKDPWGNDYQYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ"
     gene            12353..12916
                     /gene="gspH"
                     /locus_tag="RH288_001212"
     CDS             12353..12916
                     /gene="gspH"
                     /locus_tag="RH288_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001394829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HDV4030291.1"
                     /translation="MPERGFTLLEIMLVIFLIGLASSGVVQTFATDSEPPAKKAAQDF
                     LTRFAQFKDRAVIEGQTLGVLIDAPGYQFMQRRQGQWLPVSATRLSAQVTVPKQVQML
                     LQPGSDIWQKEYALELQRRRLTLHDIELELQKEAKKKTPQIRFSPFEPATPFTLRFYS
                     AAQNACWAVKLAHDGALSLNQCDERMP"
     gene            12913..13284
                     /gene="gspI"
                     /locus_tag="RH288_001213"
     CDS             12913..13284
                     /gene="gspI"
                     /locus_tag="RH288_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001709020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HDV4030292.1"
                     /translation="MKRGFTLLEVMLALAIFALAATAVLQIASGALSNQHVLEEKTVA
                     GWVAENQTALLYLMTRGQRAVRQQGESDMAGSRWYWRTTPLSTGNALLQAVDIEVSLH
                     EDFSSVIQSRRAWFSAVGGQQ"
     gene            13281..13880
                     /gene="gspJ"
                     /locus_tag="RH288_001214"
     CDS             13281..13880
                     /gene="gspJ"
                     /locus_tag="RH288_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HDV4030293.1"
                     /translation="MRRTRAGFTLLEMLVAIAIFASLALMAQQVTNGVTRVNSAVADH
                     DQKLNLMQQTMSFLTHDLTQMMPRPVRGDQGQREPALLAGAGVLASESEGMRFVRGGV
                     VNPLMRLPRSNLLTVGYRIHDGYLERLAWPLTDAAGSVKPTMQKLIPADSLRLQFYDG
                     TRWQESWSSVQAIPVAVRMTLHSPQWGEIERIWLLRGPQ"
     gene            13883..14860
                     /gene="gspK"
                     /locus_tag="RH288_001215"
     CDS             13883..14860
                     /gene="gspK"
                     /locus_tag="RH288_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HDV4030294.1"
                     /translation="MITSPPKRGMALVVVLVLLAVMMLVTITLSGRMQQQLGRTRSQQ
                     EYQQALWYSASAESLALSALSLSLKNEKRVHLAQPWASGPRFFPLPQGQIAVTLRDAQ
                     ACFNLNALAQPTTASRPLAVQQLIALISRLDVPAYRAELIAESLWEFIDEDRSVQTRL
                     GREDSEYLARSVPFYAANQPLADISEMRVVQGMDAGLYQKLKPLVCALPMTRQQININ
                     TLDVTQSVILEALFDPWLSPVQARALLQQRPAKGWEDVDQFLAQPLLADVDERTKKQL
                     KTVLSVDSNYFWLRSDITVNEIELTMNSLIVRMGPQHFSVLWHQTGESE"
     gene            14857..16035
                     /gene="gspL"
                     /locus_tag="RH288_001216"
     CDS             14857..16035
                     /gene="gspL"
                     /locus_tag="RH288_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HDV4030295.1"
                     /translation="MSSILEIFFPLCASDTVRWQRRTPDVEHGIWPDVADEQLQQWLQ
                     TDAIRLYIPGEWISVWQVELPDVARKQIPTILPALLEEELNQDIDELHFAPLNIDQQL
                     ATVAVIHQQHMRNIAQWLQENGITRATVAPDWMSIPCGFMACDAQRVICRIDECRGWS
                     AGLALAPVMFRAQLNEQDLPLSLTVVGIAPEKLSAWAGADAERLTVTALPAITTYGEP
                     EGNLLTGPWQPRVSYRKQWARWRVMILPILLILVALAVERGVTLWSVSEQVAQSRTQA
                     EEQFLTLFPEQKRIVNLRSQVTMALKKYRPQADDTRLLAELSAIASTLKSASLSDIEM
                     RGFTFDQKRQILHLQLRAANFASFDKLRSALATDYVVQQDALQKEGDAVSGGVTLRRK
                     "
     gene            16037..16573
                     /gene="yghD"
                     /locus_tag="RH288_001217"
     CDS             16037..16573
                     /gene="yghD"
                     /locus_tag="RH288_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspM family type II secretion system protein
                     YghD"
                     /protein_id="HDV4030296.1"
                     /translation="MLRDKFIHYFQQWRERQLSRGEHWLAQHLAGRSPREKGMLLAAV
                     VFLFSVGYYVLIWQPLSERIEQQETILQQLVAMNTRLKNAAPDIIAARKSATTTPAQV
                     SRVISDSASAHSVVIRRIADRGENIQVWIEPVVFNDLLKWLNALDEKYALRVTQIDVS
                     AAEKPGMVNVQRLEFGRG"
     gene            complement(16854..17006)
                     /locus_tag="RH288_001218"
                     /pseudo
     CDS             complement(16854..17006)
                     /locus_tag="RH288_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
     gene            complement(16995..17207)
                     /locus_tag="RH288_001219"
                     /pseudo
     CDS             complement(16995..17207)
                     /locus_tag="RH288_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708774.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17204..17578)
                     /locus_tag="RH288_001220"
     CDS             complement(17204..17578)
                     /locus_tag="RH288_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDV4030297.1"
                     /translation="MKTLPDTHVREASSCPSPVTIWQTLLSRLLGQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGFSTCPRSQLINSIDILRARRATG
                     LMTRDNYRTVNNITLGKHPEKR"
     gene            complement(17668..18036)
                     /gene="cbtA"
                     /locus_tag="RH288_001221"
     CDS             complement(17668..18036)
                     /gene="cbtA"
                     /locus_tag="RH288_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
                     /protein_id="HDV4030298.1"
                     /translation="MSDALSGTMLPDDNHDRPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGLFSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKGLTCKAD
                     TLGSGGYVYLAVYPTPETKK"
     gene            complement(18199..18420)
                     /locus_tag="RH288_001222"
     CDS             complement(18199..18420)
                     /locus_tag="RH288_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HDV4030299.1"
                     /translation="MKIITRGEAMRIHQQHPASRLFPFCTGKYRWHGSTEAYTGREVQ
                     DIPGVLAVFAERHKDSFGPYVRLMSVTLN"
     gene            complement(18483..18959)
                     /locus_tag="RH288_001223"
     CDS             complement(18483..18959)
                     /locus_tag="RH288_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HDV4030300.1"
                     /translation="MQQLSFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALALVDIRVPDHLIVGGNQVFSFAEHGLL"
     gene            complement(18975..19460)
                     /locus_tag="RH288_001224"
     CDS             complement(18975..19460)
                     /locus_tag="RH288_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV4030301.1"
                     /translation="MKTISHNSTTSSVSVTAASGNDQPQLVATIVPDEQRISFWPQHF
                     GLIPQWVTLEPRIFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDNDDETWVLFNA
                     MNGNRAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRII
                     D"
     gene            complement(19515..20333)
                     /locus_tag="RH288_001225"
     CDS             complement(19515..20333)
                     /locus_tag="RH288_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV4030302.1"
                     /translation="MRLASRFGYANQIRRDRPLTHEELMHYVPGIFGEDKHTSRSQNY
                     TYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLILPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETLLESLR"
     gene            complement(20433..20666)
                     /locus_tag="RH288_001226"
     CDS             complement(20433..20666)
                     /locus_tag="RH288_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001119724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDV4030303.1"
                     /translation="MPGYTEYVLAEGSFSYGQAVAVITAYRNVFIQDDPGMHFRRVIR
                     NAEGQRRWRCRNSEPDAGKVLNTRLASDGLLRQ"
     gene            complement(20745..21200)
                     /locus_tag="RH288_001227"
     CDS             complement(20745..21200)
                     /locus_tag="RH288_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030304.1"
                     /translation="MIHLFKTCMITAFILGLTWSAPLRAQDQRYISIRNTDTIWLPGN
                     ICAYQFRLDNGGNDEGFGPLTITLQLKDKYGQTLVTRKMETEAFGDSNATRTTDAFLE
                     TECVENVATTEIIKATEESNGHRVSLPLSVFNPQDYHPLLITVSGKNVN"
     gene            complement(21276..23792)
                     /locus_tag="RH288_001228"
     CDS             complement(21276..23792)
                     /locus_tag="RH288_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708766.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030305.1"
                     /translation="MLQIVGALILLIAGFAILRLLFRALISTASALAGLILLCLFGPA
                     LLAGYITERITRLFHIRWLAGVFLTIAGMIISFMWGLDGKHIALEAHTFDSVKFILTT
                     ALAGGLLAVPLQIKNIQQNGITPEDISKEINGYYCCFYTAFFLMACSACAPLIALQYD
                     ISPSLMWWGGLLYWLAALVTLLWAASQIQALKKLTCAISQTLEEQPVLNSKSWLTSLQ
                     NDYSLPDSLTERIWLTLISQRISRGELREFELADGNWLLNNAWYERNMAGFNEQLKEN
                     LSFTPDELKTLFRNRLNLSPEANDDFLDRCLDGGDWYPFSEGRRFVSFHHVDELRICA
                     SCGLTEVHHAPENHKPDPEWYCSSLCRETETLCQEIYERPYNSFISDATANGLILMKL
                     PETWSTNEKMFASGGQGHGFAAERGNHIVDRVRLKNARILGDNNARNGADRLVSGTEI
                     QTKYCSTAARSVGAAFDGQNGQYRYMGNNGPMQLEVPRDQYAGAVETMRNKIREGKVP
                     GVTDPAEASRLIRRGHLTYTQARNITRFGTIESVTYDIAEGSVVSLAAGGISFALTAS
                     VFWLSTGDRDAALQTAAVQAGKTFTRTLAVYVTTQQLHRLSVVQGMLKHIDFSTASPT
                     VRLALQKGTGAGNISALNKVMKGTLVTSLALVAVTTGPDMIKMLRGRISGAQFIRNLA
                     VASSGVAGGAVGSVAGGILFSPLGPFGALTGRVVGGVLGGMIASAVSGKIAGALVEED
                     RVKILAMIQEQVTWLAGSFLLTGHEIENLNENLARVIDQNALEIIFAAGIQQRAATNM
                     LIKPLVVSIIRQRPVMEYDASHLGNMVNRLEEALPPELPA"
     gene            complement(23913..27032)
                     /gene="ag43"
                     /locus_tag="RH288_001229"
     CDS             complement(23913..27032)
                     /gene="ag43"
                     /locus_tag="RH288_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HDV4030306.1"
                     /translation="MKRHLNTCYRLVWNHITGAFVVASELARARGKRGGVAVALSLAA
                     VTSLPVLAADIVVHPGETVNGGTLANHDNQIVFGTTNGMTISTGLEYGPDNEANTGGQ
                     WVQDGGTANKTTVTSGGLQRVNPGGSVSDTVISAGGGQSLQGRAVNTTLNGGEQWMHE
                     GAIATGTVINDKGWQVVKPGTVATDTVVNTGAEGGPDAENGDTGQFVRGDAVRTTINK
                     NGRQIVRAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQ
                     IVKNGGVAGNTTVNQKGRLQVDAGGTATNVTLKQGGALVTSTAATVTGINRLGAFSVV
                     EGKADNVVLENGGRLDVLTGHTATNTRVDDGGTLDVRNGGTATTVSMGNGGVLLADSG
                     AAVSGTRSDGKAFSIGGGQADALMLEKGSSFTLNAGDTATDTTVNGGLFTARGGTLAG
                     TTTLNNGAILTLSGKTVNNDTLTIREGDALLQGGSLTGNGSVEKSGSGTLTVSNTTLT
                     QKAVNLNEGTLTLNDSTVTTDVIAQRGTALKLTGSTVLNGAIDPTNVTLASGATWNIP
                     DNATVQSVVDDLSHAGQIHFTSTRTGKFVPATLKVKNLNGQNGTISLRVRPDMAQNNA
                     DRLVIDGGRATGKTILNLVNAGNSASGLATSGKGIQVVEAINGATTEEGAFVQGNRLQ
                     AGAFNYSLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRIVAGSRSHQTGVNGE
                     NNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSVTAGVYG
                     AAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLIHNASGLWADIVAQGTRHSMKASSD
                     NNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGYVKFGHGS
                     AQHVRAGFRLGSHNDMNFGKGTSSRDTLRGSAKHSVRELPVNWWVQPSVIRTFSSRGD
                     MSMGTAAAGSNMTFSPSQNGTSLDLQAGLEARVRENITLGVQAGYVHSVSGSSAEGYN
                     GQATLNVTF"
     gene            complement(27360..28232)
                     /locus_tag="RH288_001230"
     CDS             complement(27360..28232)
                     /locus_tag="RH288_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDV4030307.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTRHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLSGHGHSMVITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQRVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRSQAREQFTGAVDRIFDTAESVCVASVVRTALRAVRDT
                     VVSVARAVWNWIFF"
     gene            29463..30947
                     /locus_tag="RH288_001231"
     CDS             29463..30947
                     /locus_tag="RH288_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HDV4030308.1"
                     /translation="MSFGQPCDEFPLSSLPPLIRDAVIEAQQITQAPLGLVAASALGA
                     VSLVCQNLIDVCRLNTLRGPVSLFFLTLAESGERKTAVDKLLMKPLYQQEMQLYSRYK
                     SELAVWKNKEELLKAQKKALLSKLNKELRKGADESETLRQLEVLQKNSAEEPVRYKFI
                     FNDATTAAIKNQLCGKWRSVGIMSDEAGIIFDGYTLSELPFINKMWDGSVLSVDRKNE
                     PEQMIENARMTLSLMVQPGLFDRYMERKGSVARDSGFLARCLISKPATTQGKRFINGA
                     VIPGGSLTAFHERLMELARGSIEKSSEDERYCLHFSPEAQKIFIEHYNVLEQDLSPSG
                     PLSPFRGHVSKKTENIARIAALFQYFSYGEGKISADIMTSAVVISSWYTDEYKKLFAL
                     PDESELQQKDAEELFDWLIEECRGECPPRIRKNYILQCGPGRFRNRKKLNALLNILES
                     QFRLSVVPEGKTMYVLLPQIASLKLSDVSGIFTSGYHYNKLRAK"
     gene            complement(31269..31871)
                     /locus_tag="RH288_001232"
     CDS             complement(31269..31871)
                     /locus_tag="RH288_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001590672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030309.1"
                     /translation="MKPQYQTRYELLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRTTPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNCLDDWTENLKRK
                     SEKELEEWIINRQKQSAALTDLMDQYVLLAYRTTVDDKRT"
     gene            complement(31958..32164)
                     /locus_tag="RH288_001233"
     CDS             complement(31958..32164)
                     /locus_tag="RH288_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDV4030310.1"
                     /translation="MITPVSLMDDQMVDMAFITQLTGLTDKWFYKLIKDGDFPAPIKM
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            32923..33072
                     /locus_tag="RH288_001234"
     CDS             32923..33072
                     /locus_tag="RH288_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
                     /protein_id="HDV4030311.1"
                     /translation="MEKVISHTRYKLTSAELEAFNSVVDHWLAELTMNKLYDRVPASV
                     WKYVI"
     gene            33887..34456
                     /locus_tag="RH288_001235"
     CDS             33887..34456
                     /locus_tag="RH288_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDV4030312.1"
                     /translation="MTYKYNPFWQRRIRETVRHALDVHPRLTALRVDLRLPDVPAATD
                     AAVISRFINALKARIDAYQKRKRREGKRVHPTTLHYAWAREFGVLRGKKHYHLLLLVN
                     RDTWCRAGDYRDPGSLAGMIKQAWCSALGVDAGPYATLAHFPDTPAVWLERGDDTGFQ
                     QVLERAGYLAKEHTKARGTGERNFGCSRG"
     gene            34623..35024
                     /locus_tag="RH288_001236"
     CDS             34623..35024
                     /locus_tag="RH288_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030313.1"
                     /translation="MYAKSFLALDGNGRLTGARTAQTAPYDRYTCHLCGSALRYHPQY
                     DTERPWFEHTDDGLTKHGHECPYVRPERREVRLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGEQYCTNCQTGGFSIPRTTQEEICEF"
     gene            35012..35446
                     /locus_tag="RH288_001237"
     CDS             35012..35446
                     /locus_tag="RH288_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HDV4030314.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDILCCVSCGCPLTLKR
                     GNHGQPPWFEHDQMTVAAKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPRCGTGVYSRAWGRQEVPSEDARADNPLQRL"
     gene            36221..36447
                     /locus_tag="RH288_001238"
                     /pseudo
     CDS             36221..36447
                     /locus_tag="RH288_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229544.1"
                     /note="with IlvB catalyzes the formation of 2-acetolactate
                     from pyruvate, the small subunit is required for full
                     activity and valine sensitivity; E.coli produces 3
                     isoenzymes of acetolactate synthase which differ in
                     specificity to substrates, valine sensitivity and affinity
                     for cofactors; also known as acetolactate synthase small
                     subunit; frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
     gene            complement(36449..37231)
                     /locus_tag="RH288_001239"
     CDS             complement(36449..37231)
                     /locus_tag="RH288_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDV4030315.1"
                     /translation="METKQKERIRRLIEILKKTDRIHLKDAARMLEVSVMTIRRDLHQ
                     EDEPLPLTLLGGYIVMVHKPAPSMPVIQDVPRNHRDDLPIAILAAGMVNENDLIFFDN
                     GQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNS
                     SPLDSLNPRKIFISASGVHDHFGVSWFNPEDLATKRKAMARGLRKILLARHALFDEVA
                     SASLAPLSAFDVLISERPLPADYVTHCRNASVKIITPDSEDE"
     gene            37534..38454
                     /gene="rbsK"
                     /locus_tag="RH288_001240"
     CDS             37534..38454
                     /gene="rbsK"
                     /locus_tag="RH288_001240"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDV4030316.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHAIEFGKKNGIEVL
                     LNPAPALRELDMSYACKCDFFIPNETELEILTGMSVDTYDHIRLAARSLVDKGLNNII
                     VTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAA
                     LFAAFSVTGKGTQSSYPSIEQFNEFLTLNE"
     gene            38482..39798
                     /gene="fucP"
                     /locus_tag="RH288_001241"
     CDS             38482..39798
                     /gene="fucP"
                     /locus_tag="RH288_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HDV4030317.1"
                     /translation="MNDKNIIQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIGGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     ASGILLGKYLVFSEGESLEKQMSGMNAEQIHNFKVLMLENTLEPYKYMIMILVVVMVL
                     FLLTRFPTCKVAQTSHHKRPSAMDTLRYLARNPRFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASNFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNEHTEMAGAVIVMAIVGAAVVPA
                     IQGYIADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRTALAEVTAS"
     gene            39810..40823
                     /locus_tag="RH288_001242"
     CDS             39810..40823
                     /locus_tag="RH288_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDV4030318.1"
                     /translation="MSTRINLWRALFGEKPRILLENSDFTVTSFRYDSGVEGLKIANS
                     RGHLIILPWMGQMIWDAQFDGHGLTMCNMFRQPKPATEVIETYGCFAFHSGLLANGCP
                     SAEDTHLLHGEMACAAMDEAWLELDGDMLRLNGRYEYVMGFGHHYLAQPTVVLHKSST
                     LFDIKMAVTNLASVDMPLQYMCHMNYAYIPNATFSQNIPDEILRLRESVPSHVNPTAQ
                     WLAFNQRIMQGEASLSTLSQPEFYDPEIVFFADKLDAYTDQPEFRMISPDGTTFVTRF
                     YSAELNYVTRWILYNGEQQVAAFALPATCRPEGYLAAQRNGTLIQVAPQQTRTFTVTT
                     GIE"
     gene            41245..41529
                     /locus_tag="RH288_001243"
     CDS             41245..41529
                     /locus_tag="RH288_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001751479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV4030319.1"
                     /translation="MEQKTLSVEPRRSFSNEFKLQMVKLALQPRGSVARIAREHDIND
                     NLLFKWLRLSLIKGRISRRLPVTNSSGIGVELLPVEMTLDERPYPVFYAR"
     gene            complement(41745..43001)
                     /locus_tag="RH288_001244"
     CDS             complement(41745..43001)
                     /locus_tag="RH288_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011815933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDV4030320.1"
                     /translation="MDFFRFLMSDVLSEPAVLVGLIALIGLIAQKKPVTECIKGTVKT
                     IMGFVILGAGAGLVVSSLGDFANIFQHAFGIQGVVPNNEAIVSVAQKSFGKEMAMIMF
                     FAMVINIMIARFTPWKFIFLTGHHTLFMSMMVAVILATAGMTGITLIAVGSLVVGVAM
                     VFFPAIAHPYMKKVTGSDDVAIGHFSTLSYVLAGFIGSKFGNKEHSTEDMNVPKSLLF
                     LRDTPVAISFTMSIIFLVTCLFAGADAVKELSGGKNWFMFSIMQSITFAAGVYIILQG
                     VRMVIAEIVPAFKGISDKLVPNARPALDCPVVFPYAPNAVLVGFLSSFAAGLIGMFTL
                     YLLNMIVIIPGVVPHFFVGAAAGVFGNATGGRRGAILGAFAQGLLITFLPVFLLPVLG
                     DIGFANTTFSDADFGALGILLGIIVR"
     gene            complement(43014..43301)
                     /locus_tag="RH288_001245"
     CDS             complement(43014..43301)
                     /locus_tag="RH288_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004717867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDV4030321.1"
                     /translation="MKITVVCGNGLGTSLMMEMSIKSILKDLSVSADVDHVDLGSAKG
                     TPSDIYVGTKDIAEQLAAQSVAGKIVALENMIDKKAMRERLSVVLTELGAL"
     gene            complement(43317..43760)
                     /locus_tag="RH288_001246"
     CDS             complement(43317..43760)
                     /locus_tag="RH288_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001497294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDV4030322.1"
                     /translation="MLKNLLNTEVVQVVEQVKDWREAVAISCRPLIENGSIEPRYVDA
                     IYHSHDTIGPYYVVGPGIAMPHARPEEGANKLSLALTLIPSGVNFDADENDPVKLLIV
                     LAATDSTSHIEAISQLAKLFDNEKDIQAILTAKTTQDILSVIARY"
     gene            44031..45062
                     /locus_tag="RH288_001247"
     CDS             44031..45062
                     /locus_tag="RH288_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV4030323.1"
                     /translation="MEKTRKRRGTGRVTLQEVANFAGVGTMTVSRALRTPEQVSDKLR
                     EKIEQAVEELGYIPNRTAGALASGHSDTVAVLVPSLTDKASSRFMQSLQQVLNKNEFQ
                     LLLGCHEYNQLKEAEILMTLLQGNPAALVIFGSQLADKTHQILEKTNIPTINVVGSPF
                     SPAQITIETAFFEASHKLTEHLLEQGYKNIGFIGAHMENRLQRQQLNGWHKAMLSHYQ
                     NTDLVITMPDAASLQLGRYALNEILLRQPELDAVICSHEEIALGIMFECQRRLLKIPG
                     NIAVACLDGSDSCDQTHPTLTSIRIDYKKMGIETGKLLIGLLNNNHDESEESRIVQFN
                     YQIELRQST"
     gene            45190..45774
                     /locus_tag="RH288_001248"
                     /pseudo
     CDS             45190..45774
                     /locus_tag="RH288_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001411067.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(46220..46756)
                     /locus_tag="RH288_001249"
                     /pseudo
     CDS             complement(46220..46756)
                     /locus_tag="RH288_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001504106.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="enterotoxin"
     gene            46836..47857
                     /locus_tag="RH288_001250"
                     /pseudo
     CDS             46836..47857
                     /locus_tag="RH288_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612074.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            48132..48449
                     /locus_tag="RH288_001251"
     CDS             48132..48449
                     /locus_tag="RH288_001251"
                     /inference="COORDINATES: protein motif:HMM:NF024728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemagglutinin repeat-containing protein"
                     /protein_id="HDV4030324.1"
                     /translation="MSRHHSSHPLLHRRAGTILVYIIPLTPDRIDIEQPRRAGVGAGI
                     NVFASVNAAKGNGAEWTETTLDKGKTVTINSGRDMVLNGDQNVTQYVHLTFIRPNILM
                     NGD"
BASE COUNT        12154 a        12067 c        12985 g        12100 t
ORIGIN      
        1 agttacgaat tttttaacat tgttttgtca cttgcgttat taatgaataa gaaatttaaa
       61 tataagaaat cgcttttagc ggctattttg agcgcaaccc tgttagccgg ttgtgatggc
      121 ggtggttccg gatcttcctc cgatacgccg cctgtagatt ctggaacagg gtctttgccg
      181 gaagtgaaac ctgatccaac accaaacccg gagccgacgc ctgagccaac gccggagcct
      241 gaacctacgc cggaaccgac acctgatcct gagccaacac cagaaccgga gccagaacct
      301 gttcctacga aaacgggtta tctgaccctg ggcggaagcc tgcgggtaac tggtgatatc
      361 acctgtaatg atgaatccag cgatggcttt acctttacac caggcgacaa agtcacctgt
      421 gtggcaggga acaacacgac aattgctacc ttcgacaccc agtcagaagc tgcgcgtagc
      481 ctgcgtgcgg ttgaaaaagt gtcgtttagt cttgaggacg cgcaagaact ggcgggttcc
      541 gacaacaaga aaagcaatgc gctctcgctg gtcacctcca tgaacagttg cccggcgaat
      601 acagaacagg tgtgcctgga gttctcctcg gtgatcgaga gtaaacgttt cgactcgctg
      661 tataagcaaa tcgatctggc accggaagag ttcaaaaagc tggtcaatga agaggtggaa
      721 aacaatgccg cgaccgataa agcgccatcc actcatactt caccggtcgt gcccgccacc
      781 actccgggaa caaaaccgga tctaaacgct tccttcgtgt cggctaacgc ggaacagttt
      841 tatcagtatc aaccttcgga aatcattctc tcagaaggtc gcctggtcga tagtcagggg
      901 gatggtgttg ttggtgtcaa ctattacacc aattccggcc gtggtgtaac cggagaaaac
      961 ggggaatttt cctttagttg gggggaaacc atctcctttg gcatcgacac ttttgagctt
     1021 ggttctgtgc gtggtaacaa gtcgactatt gcattgactg aactgggtga tgaagttcgc
     1081 ggggcaaata tcgatcagtt gattcaccgc tattcgaagg ctggacaaaa tcacacgcgt
     1141 gtagttccgg atgaagtacg caaggttttt gctgaatatc ccaacgtgat taacgagatt
     1201 atcaatctct cgttatccaa tggtgcgacg ctgggggaag gtgagcaagt cgttaatctg
     1261 cctaacgaat ttatcgagca gtttaagacg ggtcaggcca aagagatcga taccgcgatt
     1321 tgtgcgaaaa ccgacggttg taacgaggct cgctggttct cgctgacgac gcgcaatgtt
     1381 aatgacggcc agattcaggg cgttatcaac aagctgtggg gcgtggatac gaactacaaa
     1441 tctgtcagca agttccatgt attccatgac tccaccaact tctatggcag cacgggtaat
     1501 gcgcgcggtc aggcggtggt gaatatctcc aacgcggcct tcccgattct gatggcgcgt
     1561 aatgataaaa actactggct ggccttcggc gaaaaacgcg cctgggataa aaacgagctg
     1621 gcgtacatta cggaagcgcc ttctcttgtt gagccggaaa acgttacgcg cgataccgcc
     1681 acctttaacc tgccgtttat ttcgctgggg caagtcggtg agggcaaact gatggttatc
     1741 ggtaacccac actacaacag cattttgcgt tgcccgaacg gttacagctg gaacgggggc
     1801 gttaataaag atgggcagtg tacgctcaac agcgacccgg atgacatgaa gaacttcatg
     1861 gagaacgtgc tgcgctatct gtccgacgat aaatggaagc cggacgcgaa agccagcatg
     1921 accgtaggca ccaacctgga tactgtctat tttaaacgtc atggtcaggt tacaggaaac
     1981 agcgctgcgt tcgacttcca tccggatttt gcgggcatct ctgttgagca tttaagtagc
     2041 tatggcgatc tcgatccgca ggaaatgccg ctgctgatcc ttaacggctt tgaatatgtg
     2101 actcaggtgg gtaacgatcc ttatgcaatc ccgctgcgtg cagataccag caaaccgaag
     2161 ctgactcagc aggatgtgac cgatctgatc gcctatctga acaaaggtgg atcggtgctg
     2221 atcatggaaa acgtgatgag caatcttaag gaagagagcg cgtctggttt tgtgcgtctg
     2281 ttggatgccg caggtctgtc gatggcactg aacaagtcgg tagtaaataa cgatccgcaa
     2341 gggtatccga accgcgttcg tcagcagcgc gcaacgggca tttgggtcta tgaacgttat
     2401 cctgccgtag atggtgcgct gccgtacacc atcgatagta agacagggga agttaagtgg
     2461 aaatatcagg tagaaaacaa acctgatgac aaaccgaagc tggaagttgc cagctggctg
     2521 gaagatgtag atggcaaaca ggaaacgcgt tatgccttta ttgatgaggc cgatcataaa
     2581 acagaggatt ctctgaaggc tgcgaaggag aaaattttcg ccgcgttccc ggggctgaaa
     2641 gagtgtacta atccggcata tcactatgag gtcaactgcc tggaatatcg tcctggcacg
     2701 ggggttccgg ttactggtgg catgtatgtt ccacagtata cgcaactaag ccttaacgcc
     2761 gacactgcaa aagcgatggt gcaggctgcg gatttaggca ccaacattca gcgtctgtat
     2821 cagcatgagc tctacttccg gaccaatggt cgcaaaggtg agcgtctgag cagcgtcgat
     2881 ctggaacgtc tgtaccagaa catgtcggtc tggctgtgga acgatacgag ctatcgttat
     2941 gaagaaggca aaaatgacga gctgggcttt aaaacgttca ccgagttcct gaactgctac
     3001 gccaatgatg cctatgcagg cggcaccaag tgttctgcag atctgaaaaa atcgctggtc
     3061 gataacaaca tgatctacgg tgacggtagc agcaaagcgg gcatgatgaa cccgagctac
     3121 ccgctcaact atatggaaaa accgctgaca cgcctgatgc tgggccgttc ctggtgggat
     3181 ctgaacatca aagttgatgt cgagaagtat ccgggagcag tatcggaaga gggacagaac
     3241 gttactgaaa ccatcagcct gtactcgaat ccgaccaaat ggtttgcagg taacatgcag
     3301 tcaactggcc tgtgggcacc ggctcagaaa gaggtcacca ttaagtccaa tgcgaacgtt
     3361 cctgtgaccg tcaccgtggc gctggctgac gacctgaccg gacgtgagaa gcatgaagtt
     3421 gcgctgaacc gtccgccaag agtgactaaa acgtactctc tggacgctag cggtacggtg
     3481 aagttcaagg tgccttacgg tggcctgatt tatatcaagg gcaatagctc taccaatgaa
     3541 tctgccagct tcacctttac tggcgtggta aaagcaccgt tctataaaga cggcgcatgg
     3601 aaaaacgatc tgaactcacc ggctccgctg ggtgagctgg aatcagacgc tttcgtctat
     3661 accacaccga agaagaacct gaatgccagc aattacactg gcggactgga gcaattcgct
     3721 aacgatctgg atacctttgc cagctcgatg aatgacttct acggccgtga tagcgaagac
     3781 ggtaagcacc ggatgtttac ctataaaaac ttgccgggcc acaaacatcg tttcaccaac
     3841 gatgtgcaga tctccatcgg tgatgcgcac tctggttatc cggtgatgaa cagcagcttc
     3901 tcgccgaaca gcaccacgct gccgacgacg ccgctgaacg actggctgat ctggcatgaa
     3961 gtcggtcata acgccgcaga aacgccgttg actgtaccgg gtgcaactga agtcgctaac
     4021 aacgtgctgg cgctgtacat gcaggatcgt tatctcggca agatgaaccg tgtcgctgac
     4081 gatattaccg tcgcaccgga atatctggag gagagcaaca accaggcatg ggcacgcggc
     4141 ggtgcgggtg accgtctgct gatgtacgca cagctgaagg aatgggcaga gaaaaacttt
     4201 gatatcaaga aatggtatcc agatggcact cctctgccag agttttacag cgagcgtgaa
     4261 gggatgaaag gctggaacct gttccagttg atgcatcgta aagcacgcgg cgatgaggtc
     4321 agcaatgaca agtttggcgg caagaattac tgtgctgaat ccaacggtaa cgcagcggac
     4381 acgctgatgc tgtgtgcctc ctgggtcgcc cagacggatc tttcggagtt ctttaagaaa
     4441 tggaatccgg gcgcgaatgc ttaccagctg ccgggggcga gcgagatgag cttcgagggc
     4501 ggtgtgagcc agtcggctta caacacgctc gcgtcactcg atctgccgaa accggaacag
     4561 ggaccggaaa ccattaatca ggttaccgag cataagatgt ctgccgagta agcccgtagg
     4621 ccggataagg cgctcgcgcc gcatccggca tgaaataagg cgcaccgggt taacacattt
     4681 gcccgatgcg cctgcttatc gggcctacag acggggaaag ccgcgattat ttgcgctggc
     4741 agacacccgt aggacggata aggcgtttta cgccgcatcc agcaagttac aacaaataac
     4801 ctttagccat gctttttgat gtttttcagc aataccctgc ggcgatgccc gtcctggcaa
     4861 ccgtcggagg attgattata ggtagttttt tgaatgtggt gatttggcgt taccccatca
     4921 tgctgcgcca acaaatggcg gagtttcacg gtgaaatgcc gagtgcgcag tcaaaaataa
     4981 gcctggcgct gccacgttcg cactgtccac attgtcagca gaccatccgc gttcgtgaca
     5041 atattccgct gctctcctgg ctgatgctca aagggcgctg ccgcgactgt caggcgaaaa
     5101 tcagcaagcg ttatccgctg gtggagttat tgacagcact tgcttttttg ctggcgagtc
     5161 tggtctggcc agaaagtgga tgggggctgg cggtgatgat attatccgcc tggctgattg
     5221 ccgcgagcgt catcgacctc gatcaccaat ggctgcccga tgtttttact cagggcgtat
     5281 tgtggacagg actgattgcg gcatgggcgc agcagagtcc gctcacgcta caagatgcag
     5341 tcaccggcgt cctggtggga tttatcactt tttactctct gcgttggata gccggaatag
     5401 ttctgcgtaa agaagcatta ggcatgggcg atgtattact tttcgccgcg ttaggtggct
     5461 gggtgggggc attgtcgctg cccaatgttg ctttaatcgc ctcatgctgc ggcctgatat
     5521 atgccgttat tacaaaaaga ggatcaacca cactgccttt tggaccgtgt ttaagtctgg
     5581 gcggtatagc aacactttat ctacaggcat tgttttaatg ataaccacgt cattatcaaa
     5641 gtgacatttt aactcttatt aataacctta gagattattt accatgtcga taaaacagat
     5701 gccagggagg gtattaatat cgctattgtt gagcgttaca ggattattaa gtggctgtgc
     5761 cagccataat gaaaacgcca gtttactggc gaaaaaacag gcgcaaaata tcagccaaaa
     5821 cctgccgatt aaatctgcgg gatatacctt agtgctggca caaagtagcg gcacgacgtt
     5881 aaaaatgacc attatcagcg aagcggggac tcagaccacg cagacgcctg acgccttttt
     5941 aaccagctat caacgacaaa tgtgcactga cccaacggtg aaattaatgc tcactgaggg
     6001 aattaattac agcataacga ttaatgatac acgtacaggt aaccagtatc agcggaaact
     6061 ggatcgcact acctgtggaa tagttaaagc ataacgtcgg gtagatataa attggcgcgg
     6121 gttgtttttc gtgacgcacg aatttatctc attcaatggc tgacaaaaat tcgtcacact
     6181 cttaaccaga gacaatctct taatacagac aaagagcatc tgcgaaaaat tgtacgcggg
     6241 atgttctggc tgatgctgct tattatttct gcaaaagtgg cgcattcact ctggcgctat
     6301 ttctcttttt ctgcggaata tatggctgtt tccccatcgg cgaataaacc gccccgtgcg
     6361 gatgcaaaaa cgttcgataa aaatgacgtg caattaatca gccagcaaaa ctggtttggc
     6421 aaatatcagc ccgtcgccac gccggtaaaa caacccgaac ctgcacctgt ggcagaaacg
     6481 cgtcttaatg tggtgttgcg tgggatcgcc tttggtgcca gacccggcgc ggttattgaa
     6541 gaaggtggca aacagcaggt ctatttgcag ggggaacggc ttggttctca caacgcggtg
     6601 attgaggaaa tcaatcgcga ccatgtgatg ctgcgctatc agggaaaaat agagcgcctg
     6661 agcctggcag aagaggagcg ttccacggtt gctgtgaccc gccaaaaagc catcagtgac
     6721 gaagcaaagc aagctgttgc tgaacctgct gtcagtgcgc cagttgagat cccgactgcc
     6781 gtgcgtcagg cactggcgaa agatccgcag aaaattttta actatatcca gcttacgcct
     6841 gtgcgtaagg agggaattgt cggttatgca gtgaagccgg gggcagatcg ttctctgttc
     6901 gatgccagcg gtttcaagga aggcgatatc gccattgcgc taaatcagca tgatttcact
     6961 gatccacgag caatgattgc tctgatgcgg cagttacctt caatggattc cattcaactt
     7021 acggttttac gcaagggtgc gcgccacgac atttccatcg cgctgcgcta accgcattta
     7081 atccaggaga atcattcatc gtgttttggc gtgatattac gttgtcggtc tggcgtaaga
     7141 agacaacttg cctcaaaaca aaaaagcgtt tactgccgct ggtgttggca gcggcattat
     7201 gcagttcacc ggtctgggcg gaagaagcca ctttcaccgc taattttaaa gataccgacc
     7261 tgaaatcgtt catcgaaacc gtcggcgcta accttaataa aaccatcatt atggggccgg
     7321 gcgtacaggg gaaagtgagt attcgcacca tgaccccgct caatgaacgt cagtattacc
     7381 agctattcct taacctgctg gaagcacagg ggtatgccgt cgtaccgatg gaaaacgacg
     7441 tgctgaaggt ggtgaaatcc agtgccgcga aagtcgagcc gctgccgctg gttggtgaag
     7501 gcagcgacaa ctacgcgggc gatgaaatgg tcaccaaagt agtgccggta cgtaatgtgt
     7561 cagtacgcga gctggcaccg attctgcgcc agatgatcga cagcgcaggc tcaagcaacg
     7621 ttgttaatta cgatccctcc aacgtgatta tgctcaccgg acgcgcctcc gtcgtggagc
     7681 ggctgacgga agtgatccag cgtgtggatc acgcgggtaa tcgcactgaa gaggtgatcc
     7741 cgctggataa cgcctcggct tcggaaatcg cccgcgtgct ggaaagcctg acgaaaaaca
     7801 gcggcgagaa ccagcctgcg acgctgaaat ctcaaattgt cgccgatgaa cgcaccaaca
     7861 gtgtgattgt cagtggtgac cccgccacgc gggacaaaat gcgccgtctg atccgtcgcc
     7921 tggactcaga aatggagcgc agcggcaaca gccaggtttt ctatctcaaa tacagcaaag
     7981 ccgaagatct ggtcgatgta ctgaagcagg tcagcggcac gctcacggcg gctaaagaag
     8041 aggcggaagg cacggtcggt agcgggcgtg agattgtctc catcgccgcc agcaaacaca
     8101 gtaatgccct gattgttact gcgccgcagg acatcatgca atcgctgcaa agcgtgattg
     8161 aacaactgga tattcgccgt gctcaggtgc atgtcgaggc gttgatcgtg gaagttgccg
     8221 aaggtagcaa tatcaatttc ggcgtgcagt gggcgtcgaa agatgccgga ttaatgcagt
     8281 ttgctaatgg tacgcagatc cctatcggta cgctgggcgc agccatttct caggcgaaac
     8341 cgcagaaagg ctcgacggtg atcagtgaaa acggcgctac caccattaat ccggatacca
     8401 acggcgatct ctccacgctc gcccagcttc tttccggctt tagcggtacg gcggttggtg
     8461 tggtgaaagg cgactggatg gcgctggtgc aggcggttaa aaacgactcc agctctaacg
     8521 tgctctccac gccgagcatc accacgctgg acaaccagga agccttcttc atggtgggcc
     8581 aggacgttcc ggtattaacc ggctctaccg ttggctccaa taacagcaat cctttcaata
     8641 cagtagaaag gaaaaaagtc ggcatcatgc tgaaagtcac gccgcagatt aacgaaggta
     8701 acgcggtaca gatggtgatt gagcaggaag tctcgaaggt ggaaggacag accagcctcg
     8761 acgtggtgtt tggtgagcgc aaactgaaaa ccaccgtgct ggctaacgat ggtgagctga
     8821 ttgtgcttgg tggtctgatg gacgatcagg cgggagaaag cgtggcgaaa gtgccgctgc
     8881 tgggcgatat cccattgatt ggtaacctgt ttaaatcgac ggcggataaa aaagaaaaac
     8941 gtaacctgat ggtgtttatc cgtccgacca ttctgcgtga cggtatggcg gcagacggcg
     9001 tgtcgcagcg caaatataac tatatgcgcg ccgaacagat ctatcgtgat gagcaaggtt
     9061 taagcctgat gccgcacact gcacagccgg tactgccagc gcaaaaccag gccttaccgc
     9121 cggaagttcg cgcgttcctc aatgccggga gaacgcgtta atggtgcctg tagcacagga
     9181 aaccaccgcc aacaccgtgc gtctgcccta cagtttcagc cgtcggttta gcctggtggc
     9241 atggtgcgaa gcgtcgctgg agatcctcca cgttcatccg ctatcgctct ctgttttgca
     9301 ggagctgcag cgggggctga acgcgccctt tacgctgcgg caaatcgacg aggccgaatt
     9361 tgaacagcgg ctgaatgcgg tctggcagcg ggactcttcc gaggctcgcc agctgatgga
     9421 agatctcggt tctgccgagg acttttttac cctcgcggaa gaactgccgg aaacggaaga
     9481 tctgctggaa agcgacgacg atgcgccgat catcaaactg atcaacgcca tgctggcaga
     9541 ggcaatcaaa gaaggcgctt cggatatcca cattgagacg tttgaaaaga gtctggtgat
     9601 ccgttttcgt gttgacggca cattacatga aatgctgcgt ccggggcgca aactggcctc
     9661 gctgctggtg tcgcgtatca aggtgatggc gcggctggac attgccgaaa agcgcgtgcc
     9721 gcaggatgga cgtattgcgc tgttgctggg cggccgggcg attgacgtgc gtgtctccac
     9781 catgccttct gcctggggcg agcgcgtggt gctgcgactg ctggacaaaa accaggcccg
     9841 cctgacgctg gagcgtctgg ggcttagcca gcaactgacc gcgcagttgc gccagctgtt
     9901 acacaaaccg cacggcatct ttctggtgac ggggccgacg ggttccggca aaagcaccac
     9961 gctgtacgcc ggattgcagg agctgaacaa ccattcgcgc aacattctca cggttgaaga
    10021 tcccatcgaa tacatgattg aagggatcgg tcagacgcag gttaacaccc gcgtcggcat
    10081 gacctttgcc cgtgggctgc gcgcgatttt gcgtcaggac ccggatgtgg tgatggtcgg
    10141 tgaaatccgc gataccgaaa ccgcagaaat cgccgtccag gcttcactta ccggacacct
    10201 ggtcctttcc acgctgcata ccaacacagc ggtgggggcg atcacacgtt tgcaggatat
    10261 gggcgtggag cctttcctgc tctcttccag tctgacgggc gtgatggcgc agcgactggt
    10321 tcgcacgctg tgtcccgact gccgccagcc cgcaccagcc actgacgaag aaaaacgcct
    10381 gctgggaatt accgacgccc gtaccgtcac tctgtaccat ccacagggct gtcccgcctg
    10441 taatcacaaa ggttttcgcg gacggactgc catccatgag ctgatcgtgg tggatgccac
    10501 attgcgtgat ttgatccacc gtcaggccgg ggagctggag ctggaacgtt atgtccgaca
    10561 acactctgcg ggtatccgca gcaacggcat tgagaaagtg ctcgccggag aaacctctct
    10621 cgatgaagtt ctgcgggtaa ccatggaggc gtaatggcac tgttttacta tcaggcgctg
    10681 gagcgtaatg gtcgcaaaac caaaggtatg attgaggcgg attccgcgcg tcatgcccgc
    10741 cagttgttgc gcggtaaaga gcttatcccc gtgcatattg aagcccggat gaatacttcg
    10801 tcagggggga tgttgcagcg tcggcggcac gcacatcgtc gcgtggcggc ggcagatctt
    10861 gcgctgttca cgcgccaact ggcaacgctg gtacaggcag caatgccgct ggaaacctgc
    10921 ttacaggcgg tcagtgagca aagtgaaaaa ctgcatgtaa aaagcctcgg aatggcgctg
    10981 cgcagccgga ttcaggaagg ttacaccctg tcggacagcc tgcgcgaaca tccccgcgtc
    11041 tttgattctc tgttttgttc gatggttgct gccggagaaa aatccgggca tctcgacgtg
    11101 gtgcttaatc gcctggcaga ttacaccgaa cagcgacagc gcctgaaatc acgtctattg
    11161 caggccatgc tctatccgct ggttctgctg gtggtggcaa cgggcgtggt cactattttg
    11221 ctgacggcgg tagtaccgaa aatcatcgaa cagtttgatc atctcggaca cgcgctgccc
    11281 gtctccaccc gcacgcttat tgccatgagc gatgcgttgc aggccagcgg cgtttactgg
    11341 ctggcgggtt tgctggggct tctggtgctg gggcaacggc tacttaaaaa tcctgcgatg
    11401 cgcctgcgct gggataaaac cttgctgcgc ctgcccgtga tagggcgtgt tgcgcgcgga
    11461 ctgaatacgg cgcgtttttc ccgcacgtta agcatcctca ccgccagcag tgttccgcta
    11521 ctggaaggca ttcagaccgc tgccgccgtg tcggcaaatc gctatgtcga gcaacaactg
    11581 ctgttggcgg cagatcgcgt ccgcgaagga agcagtctgc gcgctgcgct ggcggagttg
    11641 cgcctgttcc ccccgatgat gctgtacatg atcgcctccg gcgaacagag cggcgaactg
    11701 gaaaccatgc ttgaacaggc cgcagttaac caggagcggg aatttgatac ccaggtgggg
    11761 ctggcgttgg ggctgtttga gccggcgctg gtggtgatga tggcgggcgt ggtgctgttt
    11821 atcgtcatcg ccatcctcga gccgatgctg caactgaaca atatggttgg aatgtaattt
    11881 acggagttat cacatgaatt cgttatcccg cacacaaaaa ccacgggcag gttttaccct
    11941 gctggaagtg atggtggtga ttgttattct tggcgtcctg gcaagtctgg tggtgcctaa
    12001 cctgttgggc aataaagaga aagcggatcg gcaaaaagcc atcagcgata tcgtggcgct
    12061 ggaaaacgca ctggatatgt accgactgga taacgggcgt tatccaacta ccgaacaggg
    12121 gcttgaggcg ctgatccagc agccagccaa tatggcggac gcccgcaact accgtactgg
    12181 tggatacatt aaacgactgc caaaggatcc gtggggcaat gattatcagt atctcagccc
    12241 gggtgaaaaa gggctgtttg atgtttatac cctgggggcg gatggtcagg aaaacgggga
    12301 aggcgctggc gcagatatcg gtaactggaa tttgcaggag tttcagtaag cagtgcctga
    12361 acgcggattc acacttctgg aaatcatgtt ggtgattttc cttatcggcc ttgccagttc
    12421 gggcgtggta cagacgtttg cgaccgattc tgaaccgccc gcgaaaaaag cggcacagga
    12481 ttttctgact cgctttgcgc agtttaagga cagggcagtg attgaagggc agacactcgg
    12541 tgtgctaatc gacgcgcctg gctatcagtt tatgcagcgt cgtcaggggc agtggttgcc
    12601 cgtttccgcg acccggttat cggcacaggt tacggtgcca aaacaggtgc agatgctgtt
    12661 acaacccgga agtgatatct ggcagaagga gtatgcgctg gagctgcaac gtcgtcgcct
    12721 gacgctgcac gatattgaac tggagctgca aaaagaggcg aaaaagaaga cgccgcagat
    12781 ccgtttttcg ccttttgaac ccgccacgcc gtttacgctg cgcttctact cggcggcgca
    12841 aaacgcatgt tgggcggtaa aactggcgca cgatggcgcg ttatccctca atcaatgtga
    12901 tgagaggatg ccatgaagcg cggatttacc ttgctggaag tgatgctcgc gctggcgatt
    12961 tttgcgctgg ctgccacggc ggtattacag attgccagcg gtgcgctgag taatcagcac
    13021 gttcttgagg aaaaaacggt agcgggctgg gtggctgaaa accagactgc gctgctctac
    13081 ctgatgaccc gtgggcagcg ggcggtcagg cagcagggcg agagcgatat ggcaggaagc
    13141 cgctggtact ggcgaaccac accgctgagt acaggcaacg cgctgctcca ggcggtggat
    13201 attgaagtca gccttcacga agacttttcg tcggtcattc agtcacgacg cgcctggttt
    13261 agcgccgtgg gaggccaaca gtgagaagga ctcgcgctgg tttcacgtta ctggaaatgt
    13321 tggtggcaat tgccattttt gcctcgctgg cactgatggc gcagcaggtg actaacggcg
    13381 tcacgcgcgt gaatagcgcc gtcgccgatc acgatcaaaa actaaacctc atgcagcaaa
    13441 cgatgagttt tctgacccac gatctgaccc aaatgatgcc gcgtccggta agaggcgatc
    13501 agggccagcg tgaaccagct ttactggctg gcgctggcgt gctggcgtct gagagtgaag
    13561 gaatgcgttt tgtgcgcggc ggtgtggtta acccgttgat gcgtctgccg cgcagtaatc
    13621 tgctcaccgt cggttaccgc attcatgacg gttatctcga acggttagcc tggccgctga
    13681 ccgatgccgc aggcagcgtg aagccgacaa tgcaaaagtt gattccggcc gattcgctcc
    13741 gtttgcagtt ctacgacggc acgcgctggc aggagagctg gtcgtcagta caggcgatcc
    13801 ctgtggcggt acgcatgacc ctgcattcgc cgcaatgggg cgagattgaa cgcatctggt
    13861 tgttacgcgg gccgcaataa tcatgatcac ctcaccacca aaacgcggaa tggcactggt
    13921 cgtggtgctg gtattgctgg cggttatgat gctggtaacc atcacgcttt ccgggcggat
    13981 gcagcaacaa cttgggcgaa cgcgcagcca gcaggagtac cagcaggcgc tgtggtacag
    14041 cgccagtgcg gaaagcctgg cgctgagcgc gctcagtctg agcctgaaaa atgaaaagcg
    14101 cgtgcatctg gcacagccgt gggcatccgg ccctcgtttc ttccctctgc cgcaggggca
    14161 aattgcggtc accctgcgtg acgcacaggc ttgctttaac ctgaatgccc ttgctcagcc
    14221 gacaacggcg tcgcgtccgc ttgcggtaca acagttgatt gccctgatct cgcgcctcga
    14281 tgtgcctgct tatcgggccg aactgatagc cgaaagcctg tgggagttta ttgacgagga
    14341 ccgcagcgtg cagacgcgtc tgggccgtga agacagcgag tatctcgccc gctcggtgcc
    14401 gttctacgcc gccaatcaac cgctggccga tatcagcgag atgcgcgtgg tgcagggaat
    14461 ggacgccggg ctttatcaaa aactgaaacc gctggtctgt gcgctgccga tgacccgcca
    14521 gcaaatcaac atcaatacct tagacgtcac gcaaagtgtg attcttgagg cgctgtttga
    14581 cccgtggtta agccctgttc aggcgcgggc gttattacaa caacgtccgg cgaagggctg
    14641 ggaagatgtc gatcagtttc ttgcacagcc gctacttgct gacgtcgatg agcgtactaa
    14701 aaaacagcta aaaaccgtcc tgagcgtgga cagcaattac ttctggctgc gttcagatat
    14761 caccgtgaat gagattgaac tgacgatgaa ctcgttaatt gtccgcatgg gcccacaaca
    14821 cttttcggtt ctctggcatc agacaggaga aagtgagtga gttccatcct tgagattttt
    14881 ttcccgcttt gcgcctccga taccgtccgc tggcagcgcc gtacacccga cgtggaacac
    14941 ggtatctggc ctgacgttgc tgacgaacag cttcagcaat ggctgcaaac cgatgcgatt
    15001 cgactctaca ttcccggcga atggatcagc gtctggcagg ttgaactgcc tgatgtcgcc
    15061 cgcaagcaga taccgactat tctgcccgcc ttactggaag aagagctgaa ccaggatatc
    15121 gatgaactgc atttcgcccc gttgaatatc gaccagcaac tggcaaccgt agcagtgatt
    15181 caccaacagc atatgcgcaa cattgcgcag tggttgcagg aaaacggcat cacccgcgct
    15241 accgtcgcgc cggactggat gtccattcct tgtgggttta tggcttgcga tgcgcaacgg
    15301 gttatctgcc gcatcgatga atgccgggga tggagcgccg ggctggcgct ggctccggtc
    15361 atgttccgcg cccagctcaa tgagcaggat ttaccgcttt cgctaaccgt agtcggcatt
    15421 gcaccggaaa agctatcagc atgggctggc gcagacgctg aacgcctgac cgttacagct
    15481 ctgcccgcca ttaccactta tggcgaaccg gaagggaacc tgctgacagg gccgtggcag
    15541 cctcgcgtca gctaccgaaa acagtgggcg cgctggcggg tgatgattct gccgatattg
    15601 ctgattctgg ttgcgctggc agtggagcgg ggcgtgacgt tatggagcgt cagcgaacag
    15661 gtggcgcaaa gccgcaccca ggcggaggaa cagttcttaa cgttgttccc ggagcagaag
    15721 cggattgtga atttacgctc tcaggtgacg atggcgctga aaaaatatcg cccacaggcc
    15781 gacgataccc ggctgctcgc cgagttgtca gcgatagcca gcaccctgaa atcagcgtca
    15841 ctttccgaca tcgaaatgcg tggttttacc tttgatcaaa aacgccagat acttcacctc
    15901 cagctacggg ccgcgaactt tgccagtttc gacaaactgc gtagtgcact ggcaaccgat
    15961 tatgttgtgc aacaggacgc gttacagaaa gagggtgatg cggtttccgg cggcgtaacg
    16021 ttgcggagga aataacatgt tacgcgataa atttattcac tattttcagc aatggcgtga
    16081 acgccagtta agccgtggcg aacactggct ggcacaacac ctggcggggc gttctccgcg
    16141 tgaaaagggc atgttactgg cagcggtggt gttcctgttt agcgtcggat attacgtcct
    16201 catctggcag ccgttgagcg aacggattga gcaacaggag acaatattgc agcagctggt
    16261 ggcgatgaac acccgactga agaacgccgc gccggatatt attgcagcgc gaaaatctgc
    16321 cacaacaacg cctgcgcagg tatcgcgggt catcagtgac agtgcttccg cgcactcggt
    16381 ggtcatcagg cggatagccg atcgtgggga gaatattcag gtctggatag aacctgtggt
    16441 gtttaatgac ctgctgaaat ggttaaacgc actggatgaa aaatatgcgc tgcgggtgac
    16501 acaaattgat gtcagtgctg ctgagaagcc tgggatggtg aatgtgcagc ggctggagtt
    16561 tggacggggg taaagtatca ggagattaat atcaataaaa ttactctcgt taacgtggcg
    16621 agagtaattc ccccagactt tataagctaa tttttttcgt gaaggttatt gtcagatcca
    16681 aaagcaaaaa cccgccttgt gggcgggttc ttaagaatta gtggtgccgg actcggaatc
    16741 gaagaatgct tctatcatgt tgatattagt ttattttgtt tggtttggtg aaatatgtac
    16801 cctcttttgt acccgcagtc ccttttgata tcgaaaggga atcaaactcg gggtcaggct
    16861 gagagcacag aaggaaagtg cctggctatt atatcgttaa ttctgtcaat cagctccagc
    16921 cttttgaaag tgatgtgtgc agatcccttc ttaaagtatt taatgatgaa catctcatct
    16981 tcatagcgtc ctttactgca gcgtatgccg gcaagggttg caaacggtgg tagtgtgcag
    17041 gttgactgtt ggtcggattc ctccaccacg cggagtgaat aaccgttttc agcgaccttg
    17101 ttaatcagtt cagtgagatt aacaccatcg acgtcaacga caatttgccc catgttcagt
    17161 gcctgcacat taattctgtc ggcttccagc atcagggaaa gtttcatcgt ttctccggat
    17221 gcttacccag ggtaatgtta tttaccgttc tgtaattgtc gcgggtcatc aggccggtcg
    17281 cccggcgagc ccggaggata tcaatactgt ttattaactg agagcgggga caagtgctga
    17341 atcccggctg gtcggtacgc accagcgcgt atttttccac gagaaaattc accgcatcac
    17401 acagtgaaat gccagcttca atatgctgct caatcacacg ttcatcggcg aacggtgtgt
    17461 cattcagtgt aaggccgtaa tgctggccca gtagtcggga gagcagagtc tgccagatgg
    17521 tgacgggaga cgggcagctc gatgcctccc gtacgtgtgt atcgggtaat gttttcatac
    17581 tgaaggtttt cctgatatgc agagatgaaa aatggaaaag tggcgtggtg aaagcaccag
    17641 gccggagcag aaggttattc cggtggttta ctttttcgtt tcgggcgtcg gataaacagc
    17701 cagataaacg taaccaccgc taccgagagt gtcagctttg caggtcagac cttttgcata
    17761 cagcgtgacg gtatgctgat ggcggggatt cagttcaccg ctggtgagca tgagttccag
    17821 ttgtttcatc agcagcggaa aggcctggtc caggtggtac gcatctgcat cgctgaacag
    17881 gcctctgata ccggcgcggt cggcaaggta atgcaggcgg ttaccctcct gcaccagacg
    17941 tgccccgaaa cagggcgtca cggtgcaggg cagcccccac caggggcggt cgtgattgtc
    18001 gtcgggaagc attgtcccgg agagtgcgtc tgacacgata aaatcctcac agaaaatcgg
    18061 ttaagaatgg tttaacgatg acaggtcagc cggcgcgcag accgctttcg gtaaaggtgt
    18121 attcgtttat gagcagggcc tcatccacag cggcgtctga gctcagccag tcgtactcgt
    18181 tttccgggtg acggaacatc agttcagggt gacgctcatc agccggacat acgggccaaa
    18241 actgtcctta tggcgttcag caaacacggc cagcacaccg ggaatatcct gcacttcacg
    18301 accggtatac gcttcagtgc tgccgtgcca gcggtatttg ccggtacaga aaggaaaaag
    18361 acgggatgcc ggatgttgtt ggtgaatacg catggcttca ccacgggtga tgattttcat
    18421 agtgtgatac ctctgaagac agaagataaa agtgaaaaca agcgtgatgt ggttgtgacg
    18481 ggttaaagca gaccatgttc ggcaaaggag aaaacctggt tgccaccgac tatcagatgg
    18541 tccggcaccc ggatatccac cagggccagt gcctgtacca gacgttcggt gataagccgg
    18601 tctgccttac tgggtgtgac ttcaccggac gggtgattgt gtgccagcac cacggcagcg
    18661 gcattgtgat acagggcgcg tttaatcact tcacggggat ggacttccgt gcggttgatg
    18721 gtgccggtga agagggtttc accggcaatc agctgattct ggttgttcag atacagcacc
    18781 cggaattctt cacgctccag tcccgccatg ttcagaatca gccattcccg tgccgcacgg
    18841 gtggaggtga aggccacgcc gggttcatga agatggcggt ccagggtttt cagggcccgt
    18901 tgaatgaggc tgcgctcgcc gggcgtcatc tctccgggca gaaaggaaag ctgttgcatt
    18961 gtacttctct ccattcagtc gatgatgcgc ataatggcgc tgcattccgg atgctgcagg
    19021 gcgtaatccc gcagccggta ataatggacc gtcatggcat aacactccgt acgacaggca
    19081 tgatgactgt acgtcatcag acaggcagca atgccggcag cttccgggct catttcagcg
    19141 cggttaccgt tcatggcatt gaacagtacc catgtttcgt catcattgtc atccggttcg
    19201 ggtgccataa atgccccgcc gttgttcagg gtgtacagat tccagatacc accgcagtag
    19261 tcttcacaca gacggtccat ccagccgaag atacggggct ccagggtcac ccactgtgga
    19321 atgaggccaa agtgctgcgg ccagaagctg atgcgctgtt catcagggac tatggtggca
    19381 accagctgag gctggtcatt ccctgatgca gcggttacgg aaacagaaga tgtggtggaa
    19441 ttatgtgaaa tggttttcat gaaatgactc cttaaaggac aaataaatgc gtggttttca
    19501 gggtaatggc tgaatcagcg caggctctcc agcagggttt ccgccatcac ccacaatgcg
    19561 cggttgagct taatgtcagt gtcaatgctg tgaatggcac gggtatggat acgttttcct
    19621 ttagcgctgc gacctgaaat tccgcctttc agcatattct cctgaatggt ctgataagca
    19681 ctccacaggt ccttaccgta atcctcccgg cgtcgtggcg tcagaatgtc ggcggtggtg
    19741 acgggctgat gttcgtcacc ataacggtaa gtcagtgccg cctgtgccag cgcctggcgt
    19801 gccggtggcg gcagaatcag cgactgcatg gcatcacgct tttcctcaat ccggtcaaaa
    19861 acccccacca cctcgtaagc cccttcaatg actctgtcca ccacatttcc ccggtgcgga
    19921 acacgcactt cccccagaga ctgaccacag acgcatccgt tctggcagac gaacctgaag
    19981 taacccggca gcatctggta gctggaggta ccgtcatgag agttgagcag aataatttca
    20041 gggacatgtt ctccgtttat ctctccggcc cgccgcagac gcagcatgtg ttttgtgtat
    20101 ccccggcggc ccgggtcgcg cacacgggtc tggcaggcga agaatggctg aaagccttcc
    20161 cgctgcaggc tttccagtac ggtgatggtg gggatgtacg tatagttctg gcttcgggac
    20221 gtgtgtttat cttccccgaa aatccccggc acatagtgca tcagttcttc gtgtgtcagc
    20281 ggacggtcac ggcgtatctg gttcgcataa ccaaaacgac tggctagtcg cataatttgc
    20341 tccttatcgg tggttaagat ttactggtgt aataaatgaa aaagccacgt ctcccggaga
    20401 agacgcggcc tgatgggtga aatgaatgac gtttattgtc tgagaagacc gtcactggcg
    20461 agccgcgtat taagcacctt tccggcatcg ggttcagaat tccggcagcg ccagcgtcgc
    20521 tgaccttccg cgttgcggat aacccgacgg aaatgcattc ccgggtcatc ctggataaac
    20581 acattgcggt aagcggttat gacagcaacc gcctgcccgt atgagaaaga tccttcagcc
    20641 aggacatact ctgtgtaacc cggcatatct gttttctcct gataaataaa aagcctctgc
    20701 cacgcgttgt gacagaggct gaagcatgaa actgacttca gggatcagtt aacgtttttt
    20761 ccggaaacgg taatcagcag tggatggtag tcctggggat tgaaaaccga taacggcaga
    20821 ctgacacgat ggccgttact ttcttcagtt gctttaatga tttcggttgt ggcgacattt
    20881 tccacgcact ccgtttccag aaatgcgtct gtggttcgcg tggcattact gtcaccaaaa
    20941 gcttccgttt ccatttttct ggtcaccagc gtctgaccat atttgtcttt gagttgcaga
    21001 gtgatggtga gggggccaaa tccttcatcg tttccgccat tatccagccg gaactggtaa
    21061 gcacaaatat ttcccgggag ccatatcgta tctgtattgc gtatactgat gtaacgttga
    21121 tcctgtgccc ggagtggggc agaccacgtt aaccccagaa tgaaggcggt aatcatgcag
    21181 gttttgaaca ggtgaatcat ggtatttacc tctctgagtc atgacgatga cactgacaaa
    21241 tcaggtgata aagcgtaaaa ggcgcagaat agccgttatg ccggtaactc cgggggtaat
    21301 gcttcttcca gtcggttaac catattgccg agatgggatg catcatattc catgacgggg
    21361 cgttgcctga tgatactgac caccagtggt ttgattaaca tattggtcgc ggcccgttgt
    21421 tgtataccgg cggcgaaaat gatctccaga gcattctgat cgataacacg ggccagattc
    21481 tcgttcagat tttcaatctc atgtccggtc agcaggaaac tgccggcaag ccatgtcacc
    21541 tgctcctgaa tcattgccag aattttgacg cgatcttctt caaccagcgc tccggcaatt
    21601 tttcctgata cagcggaggc aatcattccc cccagaacac cgccaaccac acgccctgtc
    21661 agtgcaccaa atggtcccag tggactgaac agtatcccgc ccgccactga cccgacagct
    21721 ccacctgcca caccggaaga tgccacggca agattcctga tgaactgcgc accggagatc
    21781 cgtccccgca acattttgat catgtcaggg ccggttgtga cagctaccag tgccagagat
    21841 gtcaccagcg tacccttcat tactttgttc agggcactga tatttcctgc accggtcccc
    21901 ttctgaagag ccagtcggac agtcgggctg gcagtcgaaa aatcaatgtg cttcagcata
    21961 ccctgaacaa cactgagccg gtggagttgc tgggttgtga cgtagacagc cagtgtgcgg
    22021 gtgaaggttt ttcctgcctg gacagcagct gtctgcaggg cagcatcgcg atcgccggtg
    22081 ctgagccaga agaccgatgc cgtcagggca aaactgatcc ctccggccgc cagactgaca
    22141 accgaaccct cggcaatatc ataagtgacc gattcgatgg tcccgaaccg ggtgatatta
    22201 cgggcctgag tataagtcag atgtccccga cgaatcagcc gggacgcttc tgcgggatcg
    22261 gttacaccgg gtactttacc ttcgcggatc ttattcctca tggtttcaac agcgccggca
    22321 tactgatcac gggggacttc cagttgcatg gggccattat ttcccatgta acgatactgt
    22381 ccgttttgtc cgtcgaatgc cgcaccgacg ctacgggctg cagttgaaca atatttcgtc
    22441 tggatttctg ttccgctgac cagtctgtct gctccatttc tggcattatt atcaccgagg
    22501 atccgtgcgt ttttcagacg gactctgtcg acaatatggt ttccccgttc agcggcaaac
    22561 ccatgtccct gccctccgga agcaaacatt ttctcatttg tactccaggt ttccggcagt
    22621 ttcatgagaa tcagaccatt cgccgttgca tcggaaataa agctgttgta agggcgttca
    22681 taaatttcct gacacagtgt ttctgtttcg cgacaaagag aggagcagta ccattccgga
    22741 tccggcttat gattttccgg ggcatgatgt acttctgtca gcccgcagga ggcacagata
    22801 cgaagctcat ccacgtgatg gaatgataca aaacggcgac cttctgaaaa gggataccag
    22861 tcaccgccgt ccaggcaacg atcgagaaaa tcgtcattcg cttccggtga taaattcagg
    22921 cggttccgga agagcgtttt cagttcatca ggtgtgaatg acaggttctc tttcaactgt
    22981 tcgttaaacc ctgccatgtt tctttcatac caggcattgt tcagtaacca gtttccgtct
    23041 gccagttcaa attccctcag ctctccccgg gaaatccgtt gagaaatgag cgtcagccag
    23101 atgcgctccg tcagtgagtc aggaaggctg taatcgtttt gcaaactggt cagccacgat
    23161 ttactgttga gcaccggttg ttcttccagt gtctggctga tggcacaggt cagttttttc
    23221 agcgcctgga tttggctggc cgcccatagc agcgtcacta atgcagccag ccagtacaac
    23281 aacccgcccc accacatcag tgacggtgaa atatcgtact gtaacgcgat caatggtgcg
    23341 catgcagaac acgccataag gaaaaaggca gtataaaaac agcagtaata cccgttaatt
    23401 tccttgctga tatcttctgg tgtgatcccg ttctgctgaa tgtttttgat ctgcagggga
    23461 acagccagca gaccaccggc gagagcggtg gtcagaataa atttcacaga gtcaaaggtg
    23521 tgagcctcca gcgcgatatg tttaccatca agtccccaca tgaagctgat gatcattccg
    23581 gcaatcgtca gaaatacgcc tgccagccag cgaatatgga acaaccgggt tatgcgttcg
    23641 gtgatatagc cagccagtaa ggccgggccg aacagacaca gcaatatgag ccctgccagc
    23701 gcagaagccg tgctgattaa tgctctgaac aaaaggcgaa gaatggcaaa tcctgcgatc
    23761 agcaggatca gcgcgccgac tatctgtaac atagtcactc cgtgatgaat atcatgttat
    23821 tgttaatgcc agcgaatgtg gcgttgaata tccgttgcgc cggtccgggt cccgatcatg
    23881 atgaccggga ccacagagag tcgatggttc tgtcagaagg tcacattcag cgtggcctga
    23941 ccgttatagc cttcagcgct gctgccgctg acgctgtgga cataacctgc ctgaacgccc
    24001 agggtgatat tttcccggac acgggcttcc agtccggcct gcaggtccag tgacgtacca
    24061 ttctgtgacg gtgagaacgt catgttactg ccggctgcgg ctgtacccat gctcatgtcc
    24121 ccccgggagc tgaaggtgcg gataacagaa ggctgtaccc accagttcac cggcagttca
    24181 cgcacactgt gtttggcact gccgcgcagg gtgtcacggg atgaggtgcc tttaccaaag
    24241 ttcatatcgt tgtggctgcc cagacggaag ccggcacgca catgttgtgc actgccatgc
    24301 ccgaacttca cataaccggc gttatcctgg ccgtcatcca gggagagtcc ctgccaggtg
    24361 tactgcagtt gcggctccag catcagattg tcagtgatac tgaagggcag accggtttcc
    24421 agcgaaccca gccagcccca gccccgggcg cggaagtcgt tattgtccga tgacgctttc
    24481 atgctgtggc gggttccctg ggccacaatg tcagcccaca ggccggaggc gttgtgtatc
    24541 agattcaggt atccgcccag gctgccggca tcatcccgga ccgtgccggc acgggagccg
    24601 tcatcatcct taacatcaac ggaagaatgg ccagcagcac catatacccc cgcggtcaca
    24661 gacataccgg caacctctgt tctgagcagg tcaccctcca gacggacgaa gccatagctg
    24721 ccgctgcttt ccggcgtggc cccacgggca ataccgccat tgttatcgtg accgagatga
    24781 ccgccctgaa tgctgagacg gacgctgttg ttttcaccat ttacaccggt ctgatggctg
    24841 cgggagcctg ccacaatccg gtcatagtcc attgcctgtg tcagcatgga ggcatacagg
    24901 gggacttctg cacgataagc attttcactg cgcagatacc agctctcatc actgtcccgg
    24961 ttgagggagt agttaaaggc accggcctgc agcctgttcc cctggacaaa ggccccttcc
    25021 tccgtggtgg caccgttaat ggcttcaacc acctgaatac ccttaccgct ggtcgccagc
    25081 cccgacgcac tgttgccggc gttcaccagg ttcaggatgg tttttccggt tgccctgccg
    25141 ccgtcaatga ccagtctgtc agcattgttc tgtgccatat ccgggcgtac acgcaggctg
    25201 atggtgccat tctgtccgtt caggtttttc actttcaggg ttgccggtac gaacttccct
    25261 gtgcgggtgg aggtgaaatg aatctgtccg gcatggctga ggtcatccac caccgactgc
    25321 accgtggcgt tatcggggat attccaggtg gcaccggagg cgagagtgac attcgtgggg
    25381 tcaatggcac cgttcagcac agtgctgccg gtcagcttca gggctgtacc gcgctgagca
    25441 atgacatccg tggtgacggt actgtcgttc agcgtcagcg tgccttcatt caggttgacg
    25501 gctttctggg tgagtgtggt gttgctgaca gtgagtgtgc cacttcctga tttttccacg
    25561 ctgccgttac cggtgagaga gcctccctgc aggagtgcat cgccttcacg gatggtcagg
    25621 gtatcgttgt tcaccgtctt cccggaaagg gtaagtatgg cgccgttatt cagcgtggtg
    25681 gtgcccgcca gtgtgccgcc cctggcggtg aacagtccgc catttaccgt ggtatccgtg
    25741 gccgtatcac cggcgttcag cgtgaatgaa ctgccttttt ccagcatcag ggcatccgcc
    25801 tgaccgcctc cgatactgaa tgcctttccg tcgctccggg taccactgac agcggcaccg
    25861 gaatcggcca gcagtacacc gccatttccc atggatacgg tggtggcggt gccaccgttg
    25921 cggacatcca gcgttccgcc atcatccacg cgggtattag tggctgtgtg tccggtcagc
    25981 acatccaggc gtccgccatt ttccagtacg acattatcag ctttaccctc cacaacagag
    26041 aatgctccca ggcggtttat gccggtaacg gttgcagccg tactggtaac cagtgcgccg
    26101 ccctgcttca gggtgacatt cgtggctgta ccaccggcgt ccacctgcag tctgcccttc
    26161 tgattaacgg tggtattccc ggccacaccc ccgtttttga caatctgcca gccgtcactg
    26221 ttcacaacag tgtcagacgc tgtaccgccg ttgtgcacat actggtatcc cccattcagc
    26281 gtggtatcca gtgcgtgacc atgtacagtc tggtcgccgc cggcataaac cacagtggta
    26341 tttgccgttc cttcagctct cacaatctgg cgaccgtttt tattgatggt tgtgcgtacg
    26401 gcatccccgc gaacaaactg cccggtatca ccgttttctg catccggtcc cccttccgcc
    26461 ccggtattaa caacggtatc cgttgccact gtaccgggct tgacgacctg ccagccctta
    26521 tcattaatga cggttcctgt ggctatcgcc ccctcatgca tccactgttc gccaccattc
    26581 agcgtggtgt tcactgcccg tccctgaagg ctctgtccgc ctccggcact gataaccgtg
    26641 tctgagacac ttccaccggg gttcactctc tgaagaccac cactggtgac agtcgttttg
    26701 ttggctgttc cgccatcctg tacccattgc ccgccggtat tggcctcgtt atccggccca
    26761 tactccagcc cggtactgat ggtcattccg ttggtcgtac cgaagacaat ctggttgtca
    26821 tgatttgcca gtgttccgcc gttcacggtt tctcccgggt gcacaacgat gtcagcagcc
    26881 agcaccggga gtgacgtgac tgcggcaaga gacagtgcaa ccgccacacc gccacgttta
    26941 ccccgtgcgc gggccagttc ggaggcaacc acgaaagcgc ccgtaatgtg attccatacc
    27001 agcctgtagc aggtattcag atgtcgtttc atcagctttt ccttagattg agggtgaata
    27061 aaaaagccgg tacccacaaa cgtggatacc ggcaggtaaa gggttacagt gccggaggtc
    27121 cggctgtggg agtttctgaa ttgtggttct gttgttccct gaatgtcttt ctgtacgtat
    27181 ctgtgcatgt tactgacaaa ggttattatt agcttatcga tcgatataaa cgatcgataa
    27241 aatagatatc gatcgtttta ttctattatt gagctattgc acggacaaga gagacagtaa
    27301 cgaaaacagt gcttttgtga gcagactcag agtcagggag ggcatcagtc acgacaggtt
    27361 cagaagaaaa tccagttcca taccgcacgg gcaacagaga ccaccgtgtc acgaacagcg
    27421 cgcagggccg tacggacaac agaggcaaca cagacgctct ccgctgtgtc aaatatccgg
    27481 tccaccgcac cggtaaactg ttcacgggcc tgagagcgga cagattccgt gcgcagctcg
    27541 tcctgcagtc gggtcatcag gggactggcg gcatggtcgg gaagcgctgt catgagcgca
    27601 ctgaccagcg tatccagttc ccagccggtg cgggccgata cggccacaac cggatgtacg
    27661 ggccggaaca gacggaatac cgcctccgtt ttttcgcgaa tattctgtgc ctgtgcagga
    27721 gaaggctgaa taccggccat atcccattca tggcagggct ccgttttgtc ggcctgcgtc
    27781 accacaaaca gtacccgctg atgtccccgg tgcaggatgt gtcgccagaa atactcatcc
    27841 acagacaggg cacggtcatc ggctttaatc agccacagta ccaggtcaag ttcaggcaga
    27901 atgtcacggt acagggcctc atactctgca tccctgtccc ggctctcgcc caccccgggc
    27961 aggtcagtga taaccatgct gtgaccgtgg ccactcagac ggaagcgccg tacttcccgg
    28021 gtgccggcgt gaacatcact gaccggggtg acctccccct gaaacagtgc attacagagt
    28081 gaggatttac cggccccgct tttacccata atgccaatca cgggttcgtg acgggtgagt
    28141 ttgcgcagat gttccaggat gtgacgggaa agcgagtaag gcagggagga gagcggtttt
    28201 tcaattgcct caatggcatc agacggattc atacatgtat tcccggtgaa aaaagacaaa
    28261 accccgcgca ccggaaaggt ggcgggggat tcacggagat aatatctgtc tgaaattgtt
    28321 tttaatcgat gggattgttg cgtattaaca tgaaggagat caggacttat ccgttactgg
    28381 gtgatctcct tccatgaaaa tacgccgtta ttgttaaaca gcaggctgat ttctccgtaa
    28441 aggggaaaat atttatcggc tgcatgatta tcaggtgtgt ctgtgtttac tgctgtgagt
    28501 atttttcagt gtattgtggg ggagatgtca gtgggagata ttaaatttac atttataatt
    28561 atcttacttc ttctgtgtgt tttttataag agtgcacacg taatgatatc tgttgatacc
    28621 atgtggttaa gtgtttccct tcctggtcat gcgtaatgat taaatgcttt tgtgacacca
    28681 ttcttccggt ctgaatattt atcccgttct tttttatttg tgcagtgata ctgtcggaag
    28741 agaattcagt aatgtgaggt gtcctggtca ggataatatc tgctgagata ttattagttg
    28801 agtgtgtttt tactgagcaa aagctggctt ttaattcctg tactgaaaca ctgtcgctcg
    28861 tccggggtta actgaaactg gatgatgatg taaaatgaag gctgtttttg tgtttgtcga
    28921 agaagtgtta ttttaatcca ttctcatcat tggctggcga ttatacagaa gtatttgaag
    28981 aaaaaatggt gcattttatc tgcgtcagca gggaggaagt attttattga tgtatcagta
    29041 ttaaatggtt tttgttattt ataaatatgt catcctgtcc atagaatatt gtactcagca
    29101 ttcagtgcag gaactgtagt cttctttatt ttattcttct tcaggagggg ggggattcct
    29161 gaaggcgtta ttcccggtgt tctgtttatg attcttcccg gcaggaaacc ggtatctgca
    29221 atacccggga tgatgctttt tgttcgtacg tggttgtgta aaatttgaat agtggatgtg
    29281 ctccgaaggg aaggagggga cacacagatt cattttgtct ttcttcagca gcaaaataca
    29341 ctgtggttat tatttaacca ttaaatcaac aaaaattttt acctcatatt gatttgactg
    29401 ctatttttgc tattaatagc cagaattgca gtgcttttat atctgtgtat agtgaggtta
    29461 ctatgtcatt cggtcagcct tgtgatgagt ttcccctgag ttcgctgcct ccactcattc
    29521 gtgatgccgt tattgaagct cagcaaatta cgcaggctcc ccttgggctt gtggcagcgt
    29581 ctgccctggg cgctgtttca cttgtctgcc agaatctgat tgatgtctgc agactgaata
    29641 cactgcgggg gccggtctct ctttttttcc tgacgcttgc cgagtccgga gaacgaaaaa
    29701 ccgcagtgga caaattatta atgaagcccc tgtaccagca ggagatgcag ttatattcca
    29761 gatacaaaag tgaactggct gtctggaaaa acaaggaaga gcttttaaag gctcagaaaa
    29821 aagcattgtt gtcaaaactg aataaagaac tccgcaaagg cgcggatgag tcagaaaccc
    29881 tcagacaact ggaagtactt cagaaaaaca gtgcggaaga acctgtgagg tataaattca
    29941 tttttaatga tgccacgact gcggcaatta agaatcagct ttgtggtaaa tggcgttcag
    30001 tgggtattat gtcagatgaa gccggtatta tatttgatgg gtataccctg tctgagttgc
    30061 cttttattaa caaaatgtgg gatggctctg tattgtctgt ggacagaaag aatgaacccg
    30121 aacagatgat tgaaaatgcc agaatgacgt tatccctcat ggtgcaaccc ggtctttttg
    30181 accgatatat ggagcgaaaa ggttctgttg ccagggacag tggttttctt gcccgttgtc
    30241 ttatcagtaa acctgcaacc acgcagggga aacgctttat taacggagct gtgattccgg
    30301 gaggatcatt aacggcattt catgaacgat taatggaact ggccagaggc agtattgaaa
    30361 aatccagtga ggatgaacgg tattgtctgc atttttcgcc tgaagcgcaa aaaatattta
    30421 ttgagcacta taatgttctg gagcaggatt tatccccttc cggaccctta agcccgtttc
    30481 ggggacatgt ttcaaaaaaa acagaaaaca ttgcaagaat tgcagcgtta tttcagtatt
    30541 tcagctatgg tgaagggaaa atctctgccg atatcatgac gtctgctgtc gtaataagtt
    30601 cgtggtacac agatgaatat aaaaaattat ttgcgttacc tgatgaatct gaactgcagc
    30661 agaaggacgc cgaggagctg ttcgactggc tcattgagga gtgccgcgga gaatgcccgc
    30721 cccgtatcag gaaaaattat attctccagt gtggcccggg ccggttcaga aacaggaaaa
    30781 aactgaacgc attgctgaac attcttgaat ctcagttcag gctttctgtc gtgccggaag
    30841 gaaaaaccat gtatgttctg cttccccaga tagccagttt aaagttgtct gatgtctctg
    30901 gtatttttac ctcgggttat cactacaata agctgagagc gaagtaaccg gtgagcagtt
    30961 tttctccatt atgcttcaga cttagatgat tgattattat ggggatttca tcaccgatat
    31021 tcagatgtat gaatatcggt gatgaactaa agctcaggag ctgcgtggtg gtgatgaatc
    31081 aacaggcata taactgatac ccgccggtca gaagttccag cctgcgactt tcctgtctgc
    31141 gtgcccgcag tccggcgttc aggtgcagcg tgtgacagaa cgcacggaga gcgaaacggc
    31201 aggcagacag gccgttcagt cagccctggc accctgcccg gataccagct tccctgaaac
    31261 aactggcatc aggtgcgctt atcgtcaacc gttgtgcggt atgccaggag cacgtactga
    31321 tccatcagat ccgtcagtgc tgcgctctgc ttctgacggt tgatgatcca ttcctccagc
    31381 tctttttctg atttccgttt cagattctcc gtccagtcgt caaggcagtt tccggtcatt
    31441 aaatcaagcc agcaaagcca gaccagtttg aggcgcaact ccgtgccacc aaactgacgg
    31501 aagaggctga tcagtttatt tgccagcgaa cgctgcctca gacgttcaca ttcagacagg
    31561 agaatgcctt ccagcatcgg atgatgaacc agcagatgtt cactggtgca taaattcact
    31621 atcagatcat catccagggg cggcgtggtc cgtttgtccg gaccataaat cagccggtgc
    31681 agactctggg gtacgatggc aatctccggt ttttcaccat tgaatgacac ccacccgggc
    31741 gtcagattat ggaagtagta gatattcgga tgacacacgc cccaggatac ggcgtgccgg
    31801 gtgaagccgg tcagccattt ctggtagctt tcgtggagca gctcgtaacg ggtctgatac
    31861 tgtggtttca ttttcatatt cctcacgggg gataacaggc agcagaacgc cgccggcagg
    31921 ccggagactg cgtctgctgc agatgaacgg ttaagaatta cggacgggac tgtgcaatac
    31981 gcgcctgcag ccaggcttcc acttcgcttt tcagccatcg ggagctgcgg cccattttga
    32041 tgggcgcagg aaagtcacca tccttgatga gtttgtaaaa ccacttatcg gtcaggccgg
    32101 tcagttgagt gataaatgcc atgtcgacca tctggtcatc catcagtgaa actggggtga
    32161 tcatgagaat gttcctccgg atgttgttaa accagccggt gtggtcatga aaacaacgca
    32221 ccaccttcac cggcataaca accggggaga aacgtaaaaa ataatcggga atgtgaccgc
    32281 caggagataa acggggaggt tacggtggct gagccgtacc ggtatgccgg gtggttgtta
    32341 cgaaacgatg cttccgcacg cgtgcgcgat aaagaaggga tgattttcgt gaggaagagg
    32401 ggaaaactgg cgttctgata attgcagagt tatttacggg gcggttacga tggggcagac
    32461 cgtgtccggt gggcaggcga caggtatcac cgatgggata agactgtctg attggtatta
    32521 taaatatata agagagctca aacacatgag atcaaataca tgagttcata tatgtgaaat
    32581 aaacacggtg agtgtgatca gtgggcatga tgagaacgca gtagcaacag actgcgctat
    32641 ccctgatagc tggcgtataa cccgcgtata taaaacgtat ctgcaatgta cgtgaacaga
    32701 gtgcattaag catccgtctg agcggtaaac atatccgacc tggtgagtga cagtctgaga
    32761 gaccggttaa gtggtggctc gggagtaatg agtttggggt gggtaccaga atgccagtct
    32821 ggcggtatgc tgacagtatc acgttaattg cagcataaag tgatgagagg ctaatggaag
    32881 ttaaaaccaa agcagttccg tcgttgttca tcccgggaga cgctggaaaa agtgatttcc
    32941 cacacgcgtt ataaacttac ctctgcggaa ctggaagcct tcaactctgt ggttgatcac
    33001 tggctggcag aactgacaat gaacaagctt tacgatcgtg ttcccgcttc agtctggaaa
    33061 tatgtcatct gagcgttcgg taatcacaac tgcatcgcgc caggtgttat ccgctttgtg
    33121 attcttattg gctcttctca ggttattaaa agctgaatat gttcctgttg tcgggaacca
    33181 ggataatacc gggaacgtta agcggtatag cgacaacaaa gaattcgaaa tcaaaaggga
    33241 atggtgccgg aggcgtgggc ggtaatgggc tgattttcag gtattaccgg cttacagcgt
    33301 gtggttgata ttgaggggct gtgagtttca cgtatttgtc agaaacccag acgagttttc
    33361 ctgtatggga cgaaataagg cagcggcaat acatggaaaa atttaatatg gtatgaagga
    33421 gaacctgtcg gttacgctta atataaccgg tacactgtca gctcagggga tacatgaacc
    33481 gttatctcac cagctacaca gtatatacac actgacgctg acagtagtca gcaggaccac
    33541 aataatcagt gccagcagta tggtaacgat acggtctgta ttccggtaat agccgaaggg
    33601 gtcgacagaa ccacaatacg ggcaacacac agtattatga gtaatcgcgt ttccacagtc
    33661 ccagcacttc tttttgcgta tcaccataac tccctcctca cagccttacc cgtaaccggt
    33721 tttttacatt aaaaaaacaa cgctgaaaat tcaaccgtca gtccggagac gaccgttcgg
    33781 gttatctcag agtgcctgag atattgcctg gttggagatc acttcaggga ctctgcgcat
    33841 tttttacgac gtggctattc cgtatgaacc atacggagat ttaaccatga cctacaaata
    33901 caaccccttc tggcagcgac gtattcgtga gacggtgcgg cacgcgctgg atgttcatcc
    33961 ccgcctgacg gcacttcggg ttgatctgcg tctcccggat gtaccggcag ctacggacgc
    34021 ggctgtgata tcccgcttca tcaatgccct gaaagcccga atcgacgctt accagaagcg
    34081 taagcgtcgt gaaggtaaac gcgtgcatcc caccaccctg cattacgcct gggcccggga
    34141 gttcggggta ctcaggggca aaaaacacta tcacctcctg ctgctggtca accgggatac
    34201 ctggtgtcgt gccggcgatt accgcgatcc ggggtcactg gccgggatga ttaaacaggc
    34261 ctggtgcagt gccctggggg tggatgccgg gccttatgcc acgttggcgc attttcctga
    34321 cacgccggcg gtgtggctgg aacgcggtga tgacactggc tttcagcagg tgctggaacg
    34381 tgctggctat ctggcgaagg agcataccaa agctcgcggc accggtgagc gcaactttgg
    34441 ctgcagtcgt ggctgagccc gacagacgac ttatctgacc ttagtgtgat gacgcgttca
    34501 cagcgaccac actgattttc ccttctgaga ctgaactgaa aaccgctatt cacacctgac
    34561 cacgctgccc gtaccgggac ggctgttgcc tgcgtgtcgt ctggcggctg aggaatatga
    34621 cgatgtacgc aaaatccttt ctcgcacttg atggcaacgg gcgtctgact ggtgcccgta
    34681 ccgcacagac tgcaccttac gatcgctaca cttgccacct ttgcggcagt gcactcagat
    34741 accacccgca atacgacact gaacgtccct ggtttgaaca cactgacgac gggctgacta
    34801 agcacggtca tgagtgccct tatgtcagac cggaacgcag ggaggtacgc ttgattaagc
    34861 gtctgcagca attcgtaccg gatgccttac ccgtggtgcg taaagccagc tggcactgca
    34921 gacaatgtca ccacgattat tatggggagc agtactgcac aaactgccag accggaggat
    34981 tcagtattcc ccggacaact caggaggaaa tatgcgaatt ctgaactgtt atatggcgaa
    35041 tgacagcaaa ggccattttg ttacggcgaa agaagctgcg aagcacaacc gacaggacat
    35101 tttgtgctgt gtgtcctgtg gatgcccttt aacacttaag cggggcaatc acggacaacc
    35161 accgtggttt gaacatgacc agatgactgt tgctgcgaaa atcctgctgc gatgcacctg
    35221 gcttgacccg gcagagaaag aggcccgtcg tttgcatctg cagggtatga cggttccgga
    35281 ttatacggtg aaggtgagaa agtggttttg tgtgatgtgt gacgaagatt atgaaggaga
    35341 aaagtgctgc ccgcgttgtg gtaccggggt atacagcagg gcgtgggggc ggcaggaggt
    35401 gccgtcggaa gatgccaggg ctgataatcc gttacagagg ctgtaatggt tgcctccggc
    35461 gcagtttgcg gtgatgccgt tcccgggaat ggattgccag tgcggggact gtggagctta
    35521 attccggtat tggtggcctt tccgttgatt ttgagccaac agccctcctg tgactgacag
    35581 gctgcctcgt cattccattc gtatctccag taacaggggg ttgtattgta ttttaatgtg
    35641 ccggttcagg cgtgcgtttc ccggcgcgtc tgcaccggct taaccaaatt caacagggat
    35701 aaaatagtgt aaataaccga agtattactt gcagaatcgg gggaagcatc cggggtttta
    35761 ttcaacaggc atgggaggct ccggctctga cagacattgt actgtggaat gttgttacag
    35821 gttggggcgg caaccgtgcc aggagaccat gagccgttca cggcattaaa ggccacactt
    35881 cagtcgttta cattccctgt ggtggcaggc atcttccgtt aaggcgtcag agcgttacca
    35941 acgttatgtt gtcatggctc acctttcata gtcgatgctt atctggtgac tgaaactagc
    36001 cgcagataaa gagtgtgaag ttgataccat ggagtggagt gacgtgcagg caggagattc
    36061 gctctatgca gggttgtgag atgaattcaa accggctgtc agcgccagta atatttgaag
    36121 attcgtccgg ttgttatcca gtgtgcatta aaaacccaga cattatggac aatacaacgg
    36181 cttccataac agggaggagc ctgtttatta tccgggcgta atgactaacc tttgtgggct
    36241 ttttcccgtc gtgcttttaa cgttgaaggc attttctgcc tgccgattca ggacagcgac
    36301 aaaagccata tcagactatt ggtcaatgat gaccagcgtc tggagtagat gataagccaa
    36361 attgataaac tggaatatgt gatgaaagtg caacgtaatc agtccaatcc gacgatgttt
    36421 aacaagagta cggtgttttt tcagtaagtc attcgtcttc tgaatcaggt gtaatgatct
    36481 ttacagaagc attccggcag tgcgtaacat aatctgccgg taacggacgc tcgctaatca
    36541 gaacatcaaa tgcagagagc ggtgcgaggc tggcagaggc tacttcatcg aacaaggcgt
    36601 ggcgggcgag caaaattttc cttagtccac gggccatcgc tttacgctta gtggcaagat
    36661 cttcgggatt aaaccagctg acgccaaagt gatcatgtac accgctggcg gaaataaata
    36721 tttttcgcgg attgagagag tctaatggcg aagagttact ggcatcgtaa aaagcatcac
    36781 ttctggcacg atacgtacca ccacaaagta ttgctgtcac attaggtttt tcattcaacg
    36841 caacaaagac acgatgtgag taacagatgc cagtgaaggt gattgcatcc gggatcatgc
    36901 ttataacgag cggtatctcc tggccattat caaagaagat cagatcattt tcattaacca
    36961 ttccggcggc cagaattgca ataggtaagt catcacgatg atttctcgga acgtcctgga
    37021 ttactggcat ggatggtgcg ggtttatgca ccattacaat atagccaccc agtagggtca
    37081 gtggcagagg ttcatcttcc tgatggagat cgcgacgaat agtcattaca gaaacttcca
    37141 gcattcgtgc cgcgtctttc aaatggattc tgtcggtttt cttaagtatt tcaatcaaac
    37201 gtcggatacg ctctttttgc ttcgtttcca tcaactctct ccgtaaaatg ttataaaaat
    37261 aacattatgg cattagtaaa cattgtttta gttaccatac tatacgaccg accctttgaa
    37321 atgaaaaggg tatagactgc tgaattttcg gtattaatcc tgttaggttg cttatgatta
    37381 gatagtgttg gcctgagtga taagactgga agtctattaa ataaacatcg ggttgatgtg
    37441 ctaatcgcga tctcagtcac aaatgatgca aaagtaacat gctaatgtta tttaaatacc
    37501 attgttatgc gaaagtttat aagaggtagt gaaatggaca ttgcagttat tggttccaat
    37561 atggtggatc tcattactta cactaatcag atgcctaaag aaggagaaac tctggaagca
    37621 cctgccttca aaatcggatg tggtgggaaa ggtgctaatc aagcggtggc ggcggctaaa
    37681 ttgaattcaa aagtcctgat gctgactaaa gtaggtgatg atatttttgc ggataatact
    37741 attcgtaatc tcgaatcatg gggaattaat accacttatg ttgagaaagt cccctgtacc
    37801 agcagtggtg ttgcaccgat ctttgttaat gccaactcga gcaatagtat attaataatt
    37861 aagggagcga ataaatttct ttccccggaa gatatcgatc gagctgcaga agatctgaaa
    37921 aaatgcaaat tgatcgtttt acaactggaa gttcaactgg aaacagttta ccacgcgatt
    37981 gagtttggta agaaaaatgg tattgaagtg ttattaaatc cggctccggc attgcgtgag
    38041 ttagatatgt cttatgcctg caaatgtgat ttctttatcc cgaatgaaac agaactggaa
    38101 atattaaccg gtatgtcggt tgatacttat gatcatattc gtttggccgc acgttcgtta
    38161 gttgataaag ggctgaacaa tattattgtt accatgagcg aaaaaggcgc attatggatg
    38221 acccgcgatc aggaagtcca tgttcctgca ttcaaagtaa atgctgttga tactagtggc
    38281 gctggtgacg catttattgg ttgcttttcc cattattatg ttcaaagcgg tgatgttgaa
    38341 gccgctttga aaaaagccgc tctctttgcc gctttcagcg tcacagggaa aggtacgcaa
    38401 tcatcttatc cgagtattga acaatttaat gaatttttaa ccttaaacga ataatcatcc
    38461 tgcacagtta aaggtagcac tatgaacgat aaaaacatca ttcagatgcc tgatgggtat
    38521 ctgaataaga ctcccttgtt ccagtttatt ttgttatcgt gtttattccc gctatgggga
    38581 tgcgcagctg cattaaatga catattaatc actcaattca aaagtgtatt ttcgctaagt
    38641 aactttgctt cagcattggt gcagagcgca ttttatggag gttatttttt aattgcaata
    38701 ccagcatccc ttgtgattaa aaagaccagt tataaggtgg caattttaat tggcctgacg
    38761 ctgtatattg gtggttgtac actttttttc cctgcctcgc atatggcaac ctacactatg
    38821 ttccttgcag ctatttttgc gattgcgatt ggcctgagtt tccttgaaac tgcagcgaac
    38881 acatacagtt caatgatcgg tccaaaagcc tatgccacat tgcggctcaa tatcagccag
    38941 accttttatc cgattggtgc tgcgtctggt attttattgg gcaaatatct ggttttctcc
    39001 gagggggaaa gccttgaaaa gcagatgtca ggaatgaacg ccgagcaaat tcacaacttt
    39061 aaggtgctga tgttagagaa cacccttgaa ccgtataagt atatgattat gattctggtt
    39121 gtggtcatgg tgttgttcct tttaacccgc ttcccaacct gtaaagtggc acagacaagt
    39181 caccataaac gcccgtcagc aatggatacg ctgcgctatc tggctagaaa tccgcgcttt
    39241 cgtcgcggta ttgtggcgca gttcctttat gtgggtatgc aggtcgcagt atggtcattt
    39301 accatccgtc tggcgctgga gttgggcgat atcaacgaac gtgatgcttc aaacttcatg
    39361 gtctatagct ttgcctgctt ctttattggc aagtttatag ccaatatcct tatgacgcgt
    39421 tttaatccgg aaaaagtatt gattctctat tccgttatag gggcgctgtt cctggcatat
    39481 gttgcactgg ctccaagttt cagcgcggtc tatgtcgccg tcctggtaag tgttttgttt
    39541 ggcccttgct gggcgacgat ctatgcagga acactggata cagttgataa cgaacataca
    39601 gaaatggcag gagcagtcat tgttatggct attgtcggtg ccgcggtggt tccggcaatt
    39661 cagggatata ttgcagatat gttccactca ctacagcttt cattcctggt ttctatgctc
    39721 tgctttgtct atgtcggagt ctacttctgg cgtgaaagca aagtacgtac cgcactggct
    39781 gaagtcacag cgtcctgagg agaaccgtta tgagtacgcg tattaatttg tggcgggcgc
    39841 tttttggcga gaaacctcgt atcttgctgg aaaatagtga ttttactgtc acgtcttttc
    39901 gatatgacag cggtgtcgag gggcttaaaa ttgcaaacag tcgtggacat ttgattattc
    39961 ttccctggat ggggcagatg atttgggatg cgcaatttga tggacacggc ctcaccatgt
    40021 gcaatatgtt tcgccagcct aaaccggcga cagaggtgat agagacctat ggctgttttg
    40081 cttttcattc aggtttgctg gctaatggct gcccatctgc ggaagatact catctgctac
    40141 acggtgaaat ggcctgtgcc gcgatggatg aagcatggct ggaattagac ggagatatgt
    40201 tacgccttaa cgggcgttac gagtatgtaa tgggtttcgg tcatcattat ctggctcagc
    40261 caacagtggt ccttcacaaa tcctctacac tgttcgatat taagatggcc gtaaccaatc
    40321 tggcttctgt agatatgcca ctacaatata tgtgccacat gaattatgca tatataccaa
    40381 atgctacatt cagccagaat atcccggacg aaatattaag attgcgtgaa tcagtgcctt
    40441 cgcatgttaa tcccaccgct cagtggctgg cgtttaatca acggattatg cagggagaag
    40501 cctctctgtc gacgctgagt caaccggaat tttatgatcc agaaattgtc ttctttgcag
    40561 acaaactgga cgcttataca gatcagccag agtttcgcat gatctctccc gatggcacta
    40621 cgtttgttac tcgtttctac agtgctgaac taaattatgt gacacgctgg atcctttata
    40681 acggagagca acaggtagcc gcctttgcat tacctgcaac ctgtcggcct gaggggtatc
    40741 ttgccgcgca acgtaatggc acgctgattc aggttgcacc gcagcaaacg cgcactttta
    40801 cagtcaccac aggaattgaa taaccactca aggcctgaac agcggcgcgc ttatcgttaa
    40861 ggtaagcgcg tttttttacc cgccaggaca agactatgat agcgttgccc ttatagacga
    40921 tcacattatc gtccactcca aatttgcgca actactgtag agtggtgtac tccacagctt
    40981 ctttgaggag cttaacctcc attgttttct taccgagcaa gcactgcaac tcttttattt
    41041 atttgtagtg gtcaacaaaa actggtcaca atttcagttt ttttccagta tctattttcc
    41101 gattcgttcg gcggtaatcc accgttatat tcatgaggcc ggagtgcact ataaaagtgt
    41161 atgcgtaaac cgactgctgt atgtagccat taagccagta ttggtaacat aggtacccac
    41221 cttttcaact agtggacacc tgttatggaa caaaaaacat tatcagttga accccgcagg
    41281 tcattttcaa atgagtttaa acttcaaatg gttaaactgg ctttacaacc aaggggttct
    41341 gttgcccgta ttgcccggga gcatgatatc aatgataatc ttctgttcaa atggctcagg
    41401 ctctcgctga tcaaagggcg tatatcacgg cgtcttccgg taacgaactc ttctggcatt
    41461 ggcgttgaat tattacctgt ggagatgacg ctggatgagc ggccttaccc cgttttttac
    41521 gcgaggtaat tatgaagatc aatgactagc cgtcgaaccg tgtgcatgaa ctgctgcact
    41581 gaaacttctc agctgtaaaa taatccttac gctacgtact tctcggagcg cttacgatta
    41641 atcggatgca gtcctgactg gaagaaagaa aaatggagaa aataagagga attaatatcc
    41701 tccacgttcc tgaaatcctg gaggatatta atgtcatcaa aatattagcg aacgataatc
    41761 cctaacaaaa tacccagtgc gccaaagtca gcatcactga aggtggtgtt agcaaaacca
    41821 atatcaccca gcaccggcaa taagaatact ggcaggaagg taataagcaa gccctgagcg
    41881 aaggcaccca aaatcgcacc acgacgtcca cccgttgcat taccgaatac ccctgcagct
    41941 gcacctacga agaagtgcgg caccacacca ggaataatca cgatcatgtt cagcagatac
    42001 aacgtgaaca taccgattaa acctgcagca aagctactca ggaaaccaac cagtacagcg
    42061 ttaggtgcgt aagggaagac gaccgggcaa tcgagagcag gtctggcatt cggaaccagc
    42121 ttgtctgaaa tacctttgaa tgccgggaca atctccgcaa tcaccatgcg cacaccctgc
    42181 agaatgatgt acacgccagc tgcgaaggta atggattgca tgatagagaa catgaaccag
    42241 tttttaccac cgctaagctc tttcaccgca tctgcacccg caaacaggca cgtcaccagg
    42301 aaaattatgc tcatggtaaa agagatagca accggcgtgt cgcgcaagaa cagcagactt
    42361 ttcggcacat tcatgtcttc agtcgagtgc tctttattac caaacttgct gccgatgaaa
    42421 ccggccaata cataagataa tgttgagaag tggccgatgg caacgtcatc agaaccggtc
    42481 actttcttca tgtacggatg cgcaatagcc gggaaaaaga ccattgccac gccaacaacc
    42541 aaagagccaa cggctataag cgtaatgccg gtcatgcctg ctgttgccag aattaccgct
    42601 accatcatcg acataaacaa cgtgtgatga ccggtcagga agataaattt ccacggtgtg
    42661 aaacgggcaa tcataatgtt gataaccatc gcaaagaaca taatcatcgc catttctttc
    42721 ccgaagcttt tctgcgctac ggaaacaatg gcttcattgt tcggcactac accctgaata
    42781 ccaaaggcat gctggaaaat gtttgcgaag tcacccagtg acgacacaac taaacccgcc
    42841 cctgcgccta aaatcacaaa ccccataatg gtcttgacgg tacctttaat acattcggtt
    42901 accggttttt tctgtgcaat caggccaatc agggcgatta aaccgaccag cactgcgggt
    42961 tcggaaagta catcgctcat caaaaaacga aagaaatcca tatcgccccc agcttacagt
    43021 gcgcctaatt cggttaatac cacggacaaa cgttctctca tggctttctt atcaatcata
    43081 ttttccagtg cgacgatttt gcctgcgaca gactgcgcgg ctaactgctc ggcaatgtct
    43141 ttggtgccga catagatatc actcggcgtc cctttcgcgg agcccaggtc gacgtgatca
    43201 acatcagcgc tgacggacaa atccttcaaa atgcttttaa tgctcatttc catcatcagg
    43261 ctggtgccta agccgttacc gcaaaccact gtaattttca taaatgttcc tctggattaa
    43321 tagcgcgcaa taacagacaa aatgtcctgc gtcgttttgg ccgtcaaaat ggcctgtatg
    43381 tctttttcgt tatcgaataa cttggcgagt tgagaaatcg cttcaatgtg gctggtactg
    43441 tcggttgcag ccagcacaat cagtaatttc actggatcgt tttcatcggc atcaaaattc
    43501 acacctgaag ggatcagggt cagtgctaat gacagcttgt tagccccctc ttccgggcgc
    43561 gcatgaggca tcgcaatacc agggccaacc acatagtacg gaccgatagt gtcgtgcgag
    43621 tgatagatcg catcaacata acgcggttcg atagagccgt tttcaatcaa cggtcggcat
    43681 gaaatcgcca cggcttcccg ccagtctttg acctgttcca cgacctgaac gacctctgta
    43741 tttaatagat tttttaacat gctactgata actcccgatg ataattaaca ggagagtaga
    43801 tattttacgc attaattaat gtgatgattg tcgcatttga tagcgctatc tgataacgct
    43861 accaatcttt gtgatagcgc tatcattttt ctgccgccat gctttggcta tattcggttc
    43921 ctgcatatac aatgcaacag gatatttgct accgtgggca aaaactggaa agagtaatgg
    43981 tgaaataaaa gtaatgaaaa cagctggttg taattatcca tggagtcgaa atggaaaaaa
    44041 cacgtaagcg ccgtggtacc ggacgggtga cgctgcagga ggtcgctaac tttgcaggtg
    44101 tcggaaccat gaccgtttcc cgcgcgctga gaacaccgga acaggtttct gacaagctga
    44161 gggaaaagat agaacaggcc gtagaagagt tgggttatat tcccaacaga actgctggcg
    44221 cccttgcatc tggtcacagt gatacagtcg ccgtactggt tccttccctg acagataaag
    44281 ccagctcccg ctttatgcag tcgttgcagc aggtgcttaa taaaaatgaa ttccagctac
    44341 tgcttgggtg tcatgagtat aatcaactca aagaagctga aattctgatg acgcttcttc
    44401 aaggcaaccc ggcggcgtta gttatttttg gttctcagtt ggctgataaa actcaccaga
    44461 tactcgagaa aacaaatata cctaccatta acgttgtcgg ttcccctttc agtccggctc
    44521 aaattaccat cgaaacagca ttttttgaag catcacataa actgaccgaa catctgctgg
    44581 agcagggtta taagaatatc ggatttatcg gtgcgcatat ggaaaaccgc ctgcaacgtc
    44641 agcaactgaa cggctggcat aaagcaatgc tgagccatta ccagaacact gatcttgtta
    44701 tcacaatgcc ggatgccgca agtctgcaat tggggcgtta cgcattaaac gagatattac
    44761 tgcgacaacc agagttggat gctgtgattt gcagccacga agagattgcg ctgggtatca
    44821 tgtttgagtg tcagcggcgt ttgttaaaaa tccctggaaa tatcgctgta gcttgtcttg
    44881 acggttcaga cagttgcgat caaacacacc caaccttgac atccatccgt attgactaca
    44941 aaaaaatggg gatagagacg ggtaagttac tgattggact attgaataat aatcatgatg
    45001 aatcagaaga gtcgcgtatc gtgcaattca actaccagat agaattacgt cagagtacat
    45061 gagcctaaaa gggcactatt gcaaagttag ctattgtggt agggatagcc gtttccggct
    45121 attccccgcg cagatccgga tgtgtgctgc taacgcatcc attcctactt caggtatttg
    45181 gcgtagaagc ggatgctaaa aacttgccgc aacaccgcag tatcagcccg cagagtcgct
    45241 ctccatctcc agattatcca ttcctatatt atctctgcac cggatgaatt acgcgaacaa
    45301 ctcagaaata tgacacatat gcaacttatc aggactccgg gatcctggaa gcctagtgcc
    45361 agtgaatatc gtaatgttac caacgtttat cgcattgcat tgaaatcact tgcctgacgc
    45421 tatttcgagt tacatgatga aatcgccgac cttgatgtca tgattgcggc aattgtcgat
    45481 gaactggcat ctgaactgat taaacgtaat gctgttggat acgaaagcgc ttcgcagttg
    45541 ctcatcactg ccggagataa tccccaacgg ctaagaatag aatcaggttt tgcggtgctg
    45601 tgtggtgtca actcggttac cgtatcttct aaaaaaatga accgttaccg acttaatcgg
    45661 ggtggggagc gtgctgcaaa tagtgcactt cacatcatcg ctatcggacg tttacgaact
    45721 gacgataaaa caatgacacc tgaaccagta ttgtccttta ctttcaatac gtagctgaat
    45781 gttacctctg atacgaccga taaaatccca tccgagagat ttaatatgtc agaaccaagt
    45841 attctggaac cctgcatagg taaccatctt ttatttgttt tatagcagtt gccaactctg
    45901 aagcaggaac gacatcctca ccggcagcaa tagcagtgag acttcattcc tgatatcgtt
    45961 attaacgatc caagctatca tctgatacgt acttttcacg aagcgggtat ctggatatct
    46021 aggcaactgt ataatgccgc tacctgagtc atgtgcggca attgccgcct tgagcgcctc
    46081 gttggtctgc ctgccgacgc gtagctatag gccgaattgc caatgaaaaa ggcgcttgcg
    46141 cagcaggggg agtaaatccc tgtagctggt cttgccgagt aggctgtgcc ttagccggcc
    46201 tactcatagg tacaggcgtt tagttaacgg gtatcgcctc aaacaccagc gtttccagtg
    46261 cctgcaacgt aatcactgtt gcgtttttat actcaacggg caaggtttta ttaatgccat
    46321 ataccgcttt cagactaacc tgcgccgcgt atcctgttgg tatttcgaaa tccttcgcta
    46381 actctaggta gtaggtttgt ggcttatccg acgggttgcg caaaccaaga atggctttgt
    46441 ctttgttcca agatggccag tcgtacatgg caagcgccgt cgagtcacca ccaacccagt
    46501 gggtatcaac cagcacgctg gcattttcct tcaaccattt tgcgaccttc gccaacgtat
    46561 cccacttcac ctttttcagc acagatgggg taatatacag ctcctgcagt taggtgctgg
    46621 tcacgaagta ggtccagacc taatcgaaaa aatcgcggtc cgtttgctct ttttctagtc
    46681 cataataggc attctcggcg ctggctatcc catggtacat cagcgaattc agcgggaaca
    46741 gcgggccttt acgaatgaaa agggcttccc caagatatgc gcctgattaa ctcttatgca
    46801 atcatggggt aaacatagcc ccggagggat tcgttatgac catcacgact gtcggtatcg
    46861 atcttgttaa aaatgtgttc gctgctcact gcgttgacta acacggtaaa aactattctg
    46921 gttaaacccc aaaatatcgg atactaccat tccttagctg attgccagtt tacctctctg
    46981 tgttatcggg atggaggtat actccggggc tcactactgg acaaggttgt ttcgacaata
    47041 tggtcatgaa ccacgtctga tggttgctaa atttgtatct ccttatcgca tggctggtaa
    47101 atcaggcaaa aatgacgcaa ataatgctca ggctatctgt gaagcagttc gtcgcccaca
    47161 tatgcggttt gtaacagtga aggatgagaa ccagcaggcg atgcaatgcc tacaccgtac
    47221 cagacagggt tttatcgaag agaaaacagc aacatataac cgattgagag gtttgatatc
    47281 ggaattcagt gtcatcgccc cacaaagtac agatgccctt cgtcatatgt tttctgagca
    47341 gaagagtttt ttgccacttc aggttcaaca atacgttcat gacctgctgg tacacattga
    47401 tcgtattgaa gataatatta ctgaatatga ccggttttgt cccgcatggc aaaagcagat
    47461 caccgcagtc agcgactaat ggaactgaaa gggattagta ccacaacggc ctgtgcgctg
    47521 gtcgccatta tcggaaatgc acacgatttt aaaatgagcg acaactggca acttggctgg
    47581 gactaacact atcgcaatac agcagtagtg ggaaatcaac gcttggcagg ataactaaag
    47641 ctggcgatac gtatctgcga attctgctgg ttcagggggg cgttcggttc tgattggtgc
    47701 cgaaaaaagg actgattcat tcagtcgttg gggctgatca ctggtcgagc gcagaggata
    47761 ctggcgtacc gttgtagaga tcaccgccaa aaacgcaagg ctgtgctggg catcattgca
    47821 ttacagtgat aatttcaggc tgtactcagc cagctaaagc acaaaacaaa atacccatgt
    47881 gaccgtcaat tcgttgatga taaagggtta gaccccgtga ggcctatctg gctattgtac
    47941 agaatatacg tatccgctta acgaagaaga acctcacgcg cgtctttcat caaggtccga
    48001 gtcgatgacg actcatcatg gccatttatc gttctgttgt ctctcccctt tatttttact
    48061 gaagagcaga cagaaaccat aaacaccggc gttgacatgc cggggaagcc cttatattac
    48121 aatagagctg tatgtctcgg catcacagta gtcatccact gctgcaccgg cgtgccggga
    48181 ccatactggt ttatataatc cccctgacgc cagatagaat cgacatagaa caaccaagac
    48241 gggctggcgt cggtgccggt atcaacgtct ttgctagtgt taatgcagca aaaggcaacg
    48301 gtgctgaatg gaccgaaacg accctcgaca aaggtaaaac cgtcaccatc aacagtggtc
    48361 gggacatggt gctgaacggt gatcagaacg taactcagta cgtacatctt acgttcataa
    48421 ggccgaacat attgatgaac ggcgactgag ctgcagtagt gggctgattt ttggatgtga
    48481 ataggaaaag ggaagttagt ccttatgact ttggcatgta gtctaattcc tgatgcttgc
    48541 tatattcgaa tttgaaaagc cagcttgaac tataacccat acttttttat aactgtatta
    48601 ttctggcggc tcagaggtgc actatgaaaa ctttcgatac ccaacttgcg atgagcattg
    48661 tatcgcactc aacgggaggt tttagttatg acacactcgc tagagccttg atttctaaaa
    48721 ataaaaatga aaatcctgac gaccttcttg aatcatgtcg caatttttgt ctctctcttg
    48781 aggaaaaagg tattctgagg cgatgccaaa agtgttctca ttctcaagat gagtatttcg
    48841 agtatattcc tcactagcat cagtccctga aaaatttttc agggactgat aattccgttc
    48901 ttgtcatccc cttttttctc ctgtagcttg tgtagcacga tttagggggg cgattgtgag
    48961 caatatcaac ttaataacaa catgtacaaa cggtaaacac tacgatagtg gggatatatt
    49021 gagtctgagt caattttcat caggccggcc cccttcaaat gtgctcgtga attcttggtg
    49081 caatgctctg aatgaagcga tatctacatc tgcaactgta tgtgcagaag atctttataa
    49141 aggtgggcac tgggcgacag ctaaagcgat cttaaatgaa taccctattg atttatgggt
    49201 tctttctgcc ggtttaggcc tcctccacca caaagacaat gtagtaccgt ataaagcgac
    49261 ctttgctgtg ggctatgatg aatcaatacc attgtattca caagaa
//
LOCUS       DAPHKZ010000020        48850 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.020, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000020 DAPHKZ010000000
VERSION     DAPHKZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 48850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48850
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.020"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            263..1351
                     /gene="pdeL"
                     /locus_tag="RH288_001252"
     CDS             263..1351
                     /gene="pdeL"
                     /locus_tag="RH288_001252"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator/c-di-GMP
                     phosphodiesterase PdeL"
                     /protein_id="HDV4030325.1"
                     /translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
                     ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGSNSHRYINDN
                     HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VNKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     gene            complement(1393..2325)
                     /locus_tag="RH288_001253"
     CDS             complement(1393..2325)
                     /locus_tag="RH288_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4030326.1"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
                     TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFYAIKRSIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMTQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN"
     gene            complement(2417..2914)
                     /locus_tag="RH288_001254"
     CDS             complement(2417..2914)
                     /locus_tag="RH288_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDV4030327.1"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIRSLAVNYSGMVWAFFAALTAGWLASVSGLSAFWASVITTVPFSAVV
                     VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGVISEYGGQKLSEATT
                     KRDGY"
     gene            3172..3777
                     /locus_tag="RH288_001255"
     CDS             3172..3777
                     /locus_tag="RH288_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HDV4030328.1"
                     /translation="MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     gene            3817..4680
                     /locus_tag="RH288_001256"
     CDS             3817..4680
                     /locus_tag="RH288_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDV4030329.1"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQHLHIEMSRCRRWLSPTLQMTAV
                     NFHLIAWLQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNI
                     ASAVASMMGLGIGLTPSADDYLTGLALILFIPGHPAEKYKEEFYLGLQRGKNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMTDGCA
                     LSQTYGGNYVS"
     gene            4670..6217
                     /gene="fdrA"
                     /locus_tag="RH288_001257"
     CDS             4670..6217
                     /gene="fdrA"
                     /locus_tag="RH288_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HDV4030330.1"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGADNEQLLVEIEELFNTKAQSGSHEARYA
                     TIGSAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRK
                     PVVVCFLDRGETPVDEQGLQFARGTKEAALKAVMLSGVKQENLDLHTLNQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETMFAVMEKHGDVYSNIQPDPEFRLKDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIETI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     gene            6217..7635
                     /locus_tag="RH288_001258"
     CDS             6217..7635
                     /locus_tag="RH288_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDV4030331.1"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTAKTILHAG
                     PPITWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPILRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     AASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     gene            7685..7981
                     /locus_tag="RH288_001259"
     CDS             7685..7981
                     /locus_tag="RH288_001259"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030332.1"
                     /translation="MAQESVGLISVAHQAFVTIAGCGVNALSGLRMAQESVGLISVAH
                     QAFATTAGCGVDALSGLRVARESVGLISVAHQAFVTIAGCGVNALSGLRVAREL"
     gene            8057..9007
                     /locus_tag="RH288_001260"
     CDS             8057..9007
                     /locus_tag="RH288_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase family protein"
                     /protein_id="HDV4030333.1"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSDSQRDELQKANPDWCFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     gene            9017..10399
                     /locus_tag="RH288_001261"
     CDS             9017..10399
                     /locus_tag="RH288_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDV4030334.1"
                     /translation="MKESNSRREFLSQSGKMVTAAALFGTSVPLAHAAVAGTLNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKLHPDAT
                     LPHYDTGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFP
                     QHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDELANRMVVQQISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVWGSVAG"
     gene            10776..11825
                     /gene="yahK"
                     /locus_tag="RH288_001262"
     CDS             10776..11825
                     /gene="yahK"
                     /locus_tag="RH288_001262"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase YahK"
                     /protein_id="HDV4030335.1"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKMGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALG
                     ADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     gene            12068..12883
                     /locus_tag="RH288_001263"
     CDS             12068..12883
                     /locus_tag="RH288_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030336.1"
                     /translation="MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFK
                     VLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWSDDNALTINVQFNDFPGFYDWMD
                     YPDHPVKFVFHILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFIDSVRTDC
                     KCILLEYHMPLLRIFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYP
                     VFPESLVMLLLSVLDVKTYRDDARLNEWISNRVQELGDRYYPVNKHVKIRYTL"
     gene            13296..13541
                     /locus_tag="RH288_001264"
     CDS             13296..13541
                     /locus_tag="RH288_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030337.1"
                     /translation="MAVQLFKTLLNQIPLLSSLQSGTLPLFGYSGWGRPMKKAHTGES
                     GLKWEAKDSSKLIGNKDHALRGLSSPMAVIRQIRLIT"
     gene            complement(13558..14229)
                     /locus_tag="RH288_001265"
     CDS             complement(13558..14229)
                     /locus_tag="RH288_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HDV4030338.1"
                     /translation="MMQLVHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     gene            14376..14651
                     /locus_tag="RH288_001266"
     CDS             14376..14651
                     /locus_tag="RH288_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV4030339.1"
                     /translation="MKIISKMLVGALALAVTNVYAVELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     gene            complement(14749..16335)
                     /gene="prpR"
                     /locus_tag="RH288_001267"
     CDS             complement(14749..16335)
                     /gene="prpR"
                     /locus_tag="RH288_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HDV4030340.1"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGRFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLLHYDWPGNIRE
                     LRNMMERLALFLSVEPTPDLTPQFMQLLLPELARESAKTPAPRLLTPQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     gene            16574..17464
                     /gene="prpB"
                     /locus_tag="RH288_001268"
     CDS             16574..17464
                     /gene="prpB"
                     /locus_tag="RH288_001268"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HDV4030341.1"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDNLFARSQVK"
     gene            17904..19073
                     /gene="prpC"
                     /locus_tag="RH288_001269"
     CDS             17904..19073
                     /gene="prpC"
                     /locus_tag="RH288_001269"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HDV4030342.1"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAKHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRPFVALDKRQ"
     gene            19107..20558
                     /gene="prpD"
                     /locus_tag="RH288_001270"
     CDS             19107..20558
                     /gene="prpD"
                     /locus_tag="RH288_001270"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="HDV4030343.1"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTAMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRARLEQMPVNEYLDLYVI"
     gene            20598..22484
                     /gene="prpE"
                     /locus_tag="RH288_001271"
     CDS             20598..22484
                     /gene="prpE"
                     /locus_tag="RH288_001271"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HDV4030344.1"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGSV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDGRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVLQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     gene            22814..24073
                     /gene="codB"
                     /locus_tag="RH288_001272"
     CDS             22814..24073
                     /gene="codB"
                     /locus_tag="RH288_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDV4030345.1"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     gene            24063..25346
                     /gene="codA"
                     /locus_tag="RH288_001273"
     CDS             24063..25346
                     /gene="codA"
                     /locus_tag="RH288_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="HDV4030346.1"
                     /translation="MSNNALQTIINARLPGEEGLWQIHLQDGKISAIDAQSGVMPITE
                     NSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHHEGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
     gene            complement(25683..26582)
                     /gene="cynR"
                     /locus_tag="RH288_001274"
     CDS             complement(25683..26582)
                     /gene="cynR"
                     /locus_tag="RH288_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414872.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CynR"
                     /protein_id="HDV4030347.1"
                     /translation="MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLG
                     VPLFDRSGRTIRLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFT
                     SYFIGPLMADFYARYPSITLQLQEMSQEKIEDMLCRDELDVGIAFAPVHSPELEAIPL
                     LTESLALVVAQHHPLAVHEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVV
                     IEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQT
                     AAAKAFLHMALDKCAVVGGNESR"
     gene            26691..27350
                     /gene="cynT"
                     /locus_tag="RH288_001275"
     CDS             26691..27350
                     /gene="cynT"
                     /locus_tag="RH288_001275"
                     /EC_number="4.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase CynT"
                     /protein_id="HDV4030348.1"
                     /translation="MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRL
                     VPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCG
                     AMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANL
                     QTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTA
                     A"
     gene            27381..27851
                     /gene="cynS"
                     /locus_tag="RH288_001276"
     CDS             27381..27851
                     /gene="cynS"
                     /locus_tag="RH288_001276"
                     /EC_number="4.2.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanase"
                     /protein_id="HDV4030349.1"
                     /translation="MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVT
                     AALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQ
                     VYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     gene            27857..29038
                     /gene="cynX"
                     /locus_tag="RH288_001277"
     CDS             27857..29038
                     /gene="cynX"
                     /locus_tag="RH288_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308421.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate transporter CynX"
                     /protein_id="HDV4030350.1"
                     /translation="MRNHQKTFTMLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFS
                     VAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSALLLS
                     SALLGGVGIGIIQAVMPSVIKRRFQQRTPLVMGLWSAALMGGGGLGAAITPWLVQHSE
                     TWYQTLAWWALPAVVALFAWWWQSAREVASSHKTTTTPVRVVFTPRAWTLGVYFGLIN
                     GGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLA
                     LVLQLVGFCGFIWLPMQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGKLVAFM
                     QGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPVRFPQLWVKE
                     A"
     gene            complement(29141..29752)
                     /gene="lacA"
                     /locus_tag="RH288_001278"
     CDS             complement(29141..29752)
                     /gene="lacA"
                     /locus_tag="RH288_001278"
                     /EC_number="2.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="HDV4030351.1"
                     /translation="MNMPMTERIRAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEV
                     EKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
                     GSIVTKDIPPNVVAAGVPCRVIREINDRDKHYYFKDYKVESSV"
     gene            complement(29818..31071)
                     /gene="lacY"
                     /locus_tag="RH288_001279"
     CDS             complement(29818..31071)
                     /gene="lacY"
                     /locus_tag="RH288_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="HDV4030352.1"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     gene            complement(31123..34197)
                     /gene="lacZ"
                     /locus_tag="RH288_001280"
     CDS             complement(31123..34197)
                     /gene="lacZ"
                     /locus_tag="RH288_001280"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HDV4030353.1"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFR
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIE
                     LPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPH
                     LTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKT
                     YRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     gene            complement(34320..35402)
                     /gene="lacI"
                     /locus_tag="RH288_001281"
     CDS             complement(34320..35402)
                     /gene="lacI"
                     /locus_tag="RH288_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414879.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor LacI"
                     /protein_id="HDV4030354.1"
                     /translation="MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAE
                     LNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERS
                     GVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQTPINSII
                     FSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREG
                     DWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDT
                     EDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNT
                     QTASPRALADSLMQLARQVSRLESGQ"
     gene            complement(35479..36426)
                     /gene="mhpR"
                     /locus_tag="RH288_001282"
     CDS             complement(35479..36426)
                     /gene="mhpR"
                     /locus_tag="RH288_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator MhpR"
                     /protein_id="HDV4030355.1"
                     /translation="MIFYCALSIGRVFSATIKTCPNVHQVHHVVLTIEMSINMQNNEQ
                     TEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLHRTTVRRLLETLQEEGYVRRS
                     PSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLREVVWPTDVSTLDVDAMVVRE
                     TTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQDRKELIEMLASRPGDDYQLAR
                     EPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLRSEQRVIGCLNLVYMASAMTI
                     EQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGMHLR"
     gene            36503..38167
                     /locus_tag="RH288_001283"
     CDS             36503..38167
                     /locus_tag="RH288_001283"
                     /EC_number="1.14.13.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="HDV4030356.1"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVDDVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCLFSRELEAFSQQDDEVTLHLKTAEG
                     QREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALMREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA"
     gene            38169..39113
                     /gene="mhpB"
                     /locus_tag="RH288_001284"
     CDS             38169..39113
                     /gene="mhpB"
                     /locus_tag="RH288_001284"
                     /EC_number="1.13.11.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-carboxyethylcatechol 2,3-dioxygenase"
                     /protein_id="HDV4030357.1"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     gene            39131..39997
                     /gene="mhpC"
                     /locus_tag="RH288_001285"
     CDS             39131..39997
                     /gene="mhpC"
                     /locus_tag="RH288_001285"
                     /EC_number="3.7.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414883.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-oxonona-2,4-dienedioate hydrolase"
                     /protein_id="HDV4030358.1"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSVVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSVAFTLKWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADA
                     FNQLVLNFLARP"
     gene            40007..40816
                     /gene="mhpD"
                     /locus_tag="RH288_001286"
     CDS             40007..40816
                     /gene="mhpD"
                     /locus_tag="RH288_001286"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="HDV4030359.1"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQHDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNEIIPFSRVLQP
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRTGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS"
     gene            40813..41763
                     /gene="mhpF"
                     /locus_tag="RH288_001287"
     CDS             40813..41763
                     /gene="mhpF"
                     /locus_tag="RH288_001287"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="HDV4030360.1"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     gene            41760..42773
                     /gene="dmpG"
                     /locus_tag="RH288_001288"
     CDS             41760..42773
                     /gene="dmpG"
                     /locus_tag="RH288_001288"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HDV4030361.1"
                     /translation="MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVD
                     RETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLR
                     NNK"
     gene            43351..44562
                     /locus_tag="RH288_001289"
     CDS             43351..44562
                     /locus_tag="RH288_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414887.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxy-phenyl)propionate transporter"
                     /protein_id="HDV4030362.1"
                     /translation="MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQTVFWVGGVVPLILVPLLMRWLPESAVFAGEKQSAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRSRIQPCADA"
     gene            44664..45203
                     /locus_tag="RH288_001290"
     CDS             44664..45203
                     /locus_tag="RH288_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414888.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HDV4030363.1"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     gene            complement(45427..46260)
                     /gene="fghA"
                     /locus_tag="RH288_001291"
     CDS             complement(45427..46260)
                     /gene="fghA"
                     /locus_tag="RH288_001291"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HDV4030364.1"
                     /translation="MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAANEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPDLVMHHFPATAKKSISGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLAENKDAWLDYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     gene            complement(46353..47462)
                     /gene="frmA"
                     /locus_tag="RH288_001292"
     CDS             complement(46353..47462)
                     /gene="frmA"
                     /locus_tag="RH288_001292"
                     /EC_number="1.1.1.284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="HDV4030365.1"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     gene            complement(47497..47772)
                     /gene="frmR"
                     /locus_tag="RH288_001293"
     CDS             complement(47497..47772)
                     /gene="frmR"
                     /locus_tag="RH288_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414891.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formaldehyde-responsive transcriptional
                     repressor FrmR"
                     /protein_id="HDV4030366.1"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     gene            complement(47958..48731)
                     /locus_tag="RH288_001294"
     CDS             complement(47958..48731)
                     /locus_tag="RH288_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiO family outer membrane beta-barrel protein"
                     /protein_id="HDV4030367.1"
                     /translation="MIKRTLLAAAIFSALPAYAGLTSITAGYDFTDYSGDHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGVSLYTGPVITSYRYTH
                     YDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSVSLQR
                     IQPLTEQLNLGLTAGKVWYDTPTDDYNGLQLAAHLTWKF"
     gene            complement(48733..>48850)
                     /locus_tag="RH288_001295"
     CDS             complement(48733..>48850)
                     /locus_tag="RH288_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005140989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HDV4030368.1"
                     /translation="LPGRIISPNTQLGPRVIVERNLPAGTYSLRQELIRTGD"
BASE COUNT        11539 a        12563 c        13359 g        11389 t
ORIGIN      
        1 tttattacca aaaatgagta tctgaatttt aatattgcat tcttgcgtga ttatctcctg
       61 agtttgactt gtgattacct ttttaaggta tttagcgtaa ctgtttttga gcgagcatca
      121 gaggtaaaga taatcttctt gatagtgatg tgggatgtta tacgtatggc atcgctgatg
      181 tttatggtta ccccttatgt gtgctcagga atcgacaggt aatcactcat actgaacagc
      241 gataaaagat aaaggtgtgt tcatgaattc atgtgatttt cgtgtttttc tgcaagagtt
      301 cggtacaacg gttcatttgt cattgcctgg tagcgtatcc gagaaagaac gactgctact
      361 caagctgctg atgcagggaa tgtctgtaac agaaatatca cagtacagaa atcgcagtgc
      421 aaagacaatt tcacatcaaa agaaacagct ctttgagaaa ctggggattc agagcgatat
      481 tactttctgg cgcgatattt tctttcagta caatccggag atcatatccg ccacggggag
      541 taatagtcac agatatatta atgataatca ctatcaccat atcgtcacgc ctgaagccat
      601 cagtctggcg ttggaaaacc acgaattcaa accgtggatc caaccggttt tctgcgcgca
      661 gactggggta ctgacgggct gtgaggtgct tgtccgctgg gaacatccac aaacgggaat
      721 tatcccaccg gatcagttta ttcctctggc ggagtcatcc ggtcttattg tcataatgac
      781 ccgccaactg atgaaacaga ctgcggatat tctgatgccg gtaaaacatt tgctgccgga
      841 caatttccat attggcatca acgtctcggc gggttgtttt ttggcagcgg gatttgaaaa
      901 agagtgtctg aacctggtta ataaattagg taacgataaa atcaagctgg ttctcgagct
      961 aacggaacgt aaccctattc cggtaacgcc agaagccaga gcgatatttg acagccttca
     1021 tcagcacaac attacctttg cgctggatga ctttggtacg ggttatgcga cctatcgtta
     1081 cttgcaggcg ttcccggtcg attttattaa gatcgataag tcatttgtgc aaatggcgag
     1141 tgtcgacgaa atctccggtc atattgtgga caatattgtc gaactagcgc gtaagcctgg
     1201 tctgagtatc gtggcggaag gggtagaaac ccaggagcag gcggatttaa tgatcggtaa
     1261 aggcgttcac tttttgcagg gctatttgta ctctccgcca gtaccgggta ataaatttat
     1321 ctctgaatgg gtaatgaaag caggtggttg atgtaaaccg ctattcacag cgcatcggga
     1381 ggttggcagc gattaattct cccgatgcag taaatcctga tagatccccg ttaatatgcc
     1441 atttggcgca aattgttttt taatccactg cgtcacctga cccgtagcag aatgctgagt
     1501 cgccagtaac atgcgcgaat cctggcgcgg attatggatt tgtcgggtaa ccagcaggga
     1561 ttgcgtcatc gcctcacgga ccatgtaatc cggcaaaaaa ccaattcctt cacctaaaat
     1621 ctggcactga catttggtgt tgaaatctgg caccagaatt gactcctgcc cgtgcagcaa
     1681 ccagcccact tttttattaa tcgtatgcgc ggtgtcctcc accataatat tagggtagag
     1741 acgcagttgg ctttcggcga tgggttccgg cacaaaggct aacgggtgat ccggggcgat
     1801 agcaaaagcc cagcgaatcg cgccaatttc agtgtaatca ataccgccgc cgtccagtag
     1861 tgtatcgggt gcgccgatgg cgatattggc ctgattatta ataatcgcat cccagacgcc
     1921 gttatacact tcggtggtga cggtaatctg gcaggtagga aactgctttt tcagcacctg
     1981 taacaagcgt gcggtgtgtt tgggcgtata aagcagctga ttaatacaaa tgcgcacacg
     2041 cgcttctatg ccctgcgaaa tagtatcgat actgcgtttg atggcataaa aatcattcag
     2101 caggtcggta gctttgcgga aaaaataacg cccggactcc gttaactcaa tgctgcgggt
     2161 actgcgagtg aacagcacca catccagccc cgtctccata cgcttaatgg tgtagctaat
     2221 ggcggaagtg gttaaaccca actcttctgc ggctttactg aagctgccaa aacgcgcagc
     2281 ggtagtaaat gccaacagat tctcttcggt aaaaattgag ttcattaaac cattctcgcc
     2341 attatctact atgaatttct ccagctatga ctgtagaggt atcggttaaa gatagataat
     2401 catttttgaa taacttttaa tacccgtcgc gtttagtcgt cgcttcgctt aatttttgtc
     2461 caccatattc tgaaattacc cccacgcagt tacccgccag aaaacccagt aacgtcaccg
     2521 tccagttcat cccgctggca aaaaacagcg tcatgccgag aaagccaccg ggaataaagg
     2581 acagtaacca gaaacgccct tgccagacca ctaccgccga gaagggtacg gtagtaatta
     2641 cgctcgccca gaacgcggac agtccactta cagaggccag ccaaccagca gtcagcgcgg
     2701 cgaaaaacgc ccacaccatc ccggaataat taaccgccag acttctgata aaccccgatt
     2761 taccgccgcc tgcggcataa aaactgcaaa aggcgacgaa gccaatggtt cctaataatt
     2821 cccatccttg agagagcccg acatgtgaag acactaactg ccaaagccct gcacaaatac
     2881 cgacggtgac acccgttgcc gtgagtccgt tcatcttgtt cccctctggt tagacatgga
     2941 cgaaagctac tcttacatgt gcagactata gagaaataaa acctgattga gtgaaagggt
     3001 atcgggtcaa agaaacaaat attgcactac cgcacactgc gaaaagattg ttgaatatta
     3061 ttcaacaaaa aggcgagata cggcgaatta aatttaagcg ggttctttta tcagattatc
     3121 gttgctattc tcaattcatc gaaaacagcc acaaaaacca ggggaatgtg aatgagtata
     3181 aaaaatctac ctgccgacta tttattggct gcacaacagg gtgatatcga taaagtaaaa
     3241 acctgccttg cgctgggtgt cgatattaat acctgcgatc gtcaggggaa aacggcaatt
     3301 acgctggcaa gtttatatca gcaatatgct tgcgttcagg cattaattga tgccggagcg
     3361 gatattaata agcaagatca tacctgttta aatccttttt taattagctg tctgaacgat
     3421 gatttaacgc tactacgaat tattttaccg gctaaacccg atcttaattg cgtaacccgt
     3481 tttggcggtg tcggcctgac gcctgcctgt gaaaaaggcc atttaagtat tgtaaaagag
     3541 cttttggcgc atacggagat taacgttaac cagaccaacc atgtaggctg gacgccgcta
     3601 ctggaagcga ttgtgcttaa tgatggtggt attaaacagc aggcgattgt gcagttattg
     3661 ctggaacacg gtgccagccc gcatctgacc gataaatatg gcaaaacgcc actggaactg
     3721 gcgcgggaac ggggctttga agagattgcg cagttactga ttgccgcagg tgcataaacc
     3781 gggaggcttg ctatcaacac accagaaaga cggtgtgtgt gggcgctaac tgcggatgcg
     3841 gattttctgg cgcagcgggg gcaaggacag gttgaacagg tctttgccag agcggtaaat
     3901 atcgcactcc cggctcgcca gcagttgctg acgctgcttt gtgaagagta cgacaatgcg
     3961 ccaaacagtt gtcggttggc actcactcac tttgatgatc tgttccggca tggtgataag
     4021 gttcagtttg acgatcaagg tattacggtt ggtcaacatc ttcatataga gatgagtcgt
     4081 tgtcggcgtt ggctgtcccc aaccttgcaa atgaccgctg tgaattttca ccttatcgcc
     4141 tggctacagt ggcacgacat tattcatcag cacctggggg aaaatgaaac cctgtttaat
     4201 tatcgcggcg ataatccgtt ttatcaggcg ttaaataaag aattacatat taaacgacgg
     4261 gcagttattc aggccgtaaa cgataaacaa aatatcgcct cagcggtcgc cagtatgatg
     4321 gggttaggga ttggccttac gccatcagcc gacgattatt taacaggtct ggcgcttatt
     4381 ttatttattc ccgggcatcc ggcggaaaaa tacaaagagg aattttatct cggtctgcaa
     4441 cgcggcaaaa ataataccac attattaagt gccataacgc tggaagccgc attacaacaa
     4501 cgctgccggg aaaatattca tcgttttatt cacaacatta tttatgacat ccctgggaac
     4561 gcaactcagg caatagaaaa aattaaacat attggctcca gttccggctg cgacatgctg
     4621 tatggcatga ccgatggttg tgcgctgagc caaacctacg gagggaatta tgtcagttaa
     4681 aatagtcatt aaaccgaata cctattttga ttctgtctcg ctgatgtcta tctccacgcg
     4741 tgcaaataaa ctcgacggcg tcgagcaggc atttgtggcg atggcgaccg aaatgaataa
     4801 aggcgtgctg aagaatttag gactgctgac gccggagctg gagcaggcga aaaacggcga
     4861 cctgatgatt gtcatcaatg gtaaatcggg tgcggacaac gagcagttgc tggtggagat
     4921 tgaagaactg ttcaacacca aagcgcaaag cggctcgcac gaggcgcgtt acgccactat
     4981 tggcagcgcc aaaaagcata tcccggaaag taacctggcg gtgatttcgg tcaacggtct
     5041 gtttgccgct cgcgaagcgc gtcaggcgct gcaaaacgat ctcaacgtga tgctgttttc
     5101 cgataacgtc tcagttgaag atgaactggc gctcaagcaa ctggcccacg aaaaagggct
     5161 gctgatgatg gggccagact gtggcacggc gattatcaac ggcgcggcgc tctgttttgg
     5221 taacgccgtg cgtcgcggca acatcggtat tgttggcgca tccggcaccg gcagtcagga
     5281 gttgagcgtc cgcattcatg aatttggcgg cggcgtttcg caactgattg gcaccggcgg
     5341 gcgcgacctg agcgagaaaa tcggcggcct gatgatgctc gacgccatcg ggatgctgga
     5401 aaacgatccg caaactgaaa tcattgcgct tatctccaaa ccgcctgcgc ctgcggtggc
     5461 ccgcaaagtg ctggaacgtg cgcgcgcctg ccgcaagccg gtggtcgtct gcttcctcga
     5521 tcgtggcgaa acgccagtgg atgagcaggg gctacagttt gcccgcggca ccaaagaggc
     5581 agcgctaaaa gcggtgatgc tctccggcgt gaaacaggaa aatctcgacc tgcatacgct
     5641 taaccagccg ttgattgcgg atgtgcgtgc gcgtctgcaa ccgcagcaga aatacattcg
     5701 tggcctgttc tgcggcggca cgctgtgcga cgaaaccatg ttcgcggtga tggaaaaaca
     5761 tggcgatgtc tacagcaaca ttcagcccga tccggaattc cgcctgaaag atatcaaccg
     5821 cagcatcaaa cacaccttcc tcgactttgg cgatgacgac ttcaccaacg gcaagccgca
     5881 cccgatgatt gaccccacca accgcatcag tcgcttgatc gaagaggcgc gcgatccaga
     5941 agtggcggtg atcgtgatgg attttgtgct cggatttgga tcgcatgaag atccggtcgg
     6001 ctccaccatc gagacgatca aagaagcgaa agcgatcgcc gctgccgaag gacgcgagtt
     6061 gatcattctc gcctatgtgc tgggtaccga tcttgatacg ccatcgttag aacaacaaag
     6121 ccagatgttg cttgatgccg gagtgattct ggcgagcagc agcaccaata ccggattgct
     6181 ggcgcgtgaa tttatctgca aaggggagga agcctgatga gccagtcact gtttagccaa
     6241 ccattgaacg ttattaacgt cggcatcgcc atgtttagcg atgacctgaa aaagcagcat
     6301 gtagaagtga ctcaactcga ctggacgccg ccggggcagg gcaatatgca ggtggtgcag
     6361 gcgctggata acattgccga ttcgccgctg gcggacaaaa tcgccgccgc taaccagcag
     6421 gcgctggagc gtattatcca gtcgcatccg gtgctgattg gttttgatca ggcgattaac
     6481 gtggtgccgg gcatgacggc gaaaaccatt cttcacgccg ggccgccgat cacctgggaa
     6541 aaaatgtgcg gcgcgatgaa aggcgcggtc accggagcgc tggtgttcga aggactggcg
     6601 aaagatctcg acgaggcggc tgaactggcg gcttccgggg agatcacctt ctcgccgtgt
     6661 cacgagcacg actgcgtggg atcgatggcg ggtgttacct cggcctcgat gtttatgcac
     6721 atcgtaaaaa acaaaaccta cggcaacatc gcttatacca acatgagcga gcagatggcg
     6781 aagattttgc gtatgggcgc taacgaccag agcgtgattg accgcctgaa ctggatgcgt
     6841 gatgtgcagg gaccaatact gcgcgacgcg atgaaaatta tcggcgaaat cgatctgcgc
     6901 ttaatgctgg cgcaggcgct gcatatgggc gatgagtgcc ataaccgcaa taacgccggg
     6961 acgacactgc tgattcaggc gctgacgccg gggattattc aggcgggtta ttccgtcgag
     7021 caacagcgcg aagtgtttga gtttgccgcc agcagcgact acttctccgg cccgacgtgg
     7081 atggcgatgt gtaaagcggc gatggatgcg gcgcatggca tcgaatacag caccgtggtc
     7141 accaccatgg cgcgtaacgg cgtcgagttc ggcctgcggg tcagcggcct gccggggcaa
     7201 tggtttaccg gcccggcgca gcaggtgatc ggcccgatgt ttgccggtta taagccggaa
     7261 gattcggggc tggatatcgg cgacagcgcc atcaccgaaa cctacggtat tggcggattt
     7321 gctatggcga ccgcgcccgc tatcgtcgcg ctggtgggcg gcacggtgga agaagctatt
     7381 gatttctccc gtcagatgcg cgaaatcacc ctcggtgaaa accccaacgt caccattccg
     7441 ctgctcggtt ttatgggcgt gccgtcggca atcgacatca cccgcgtggg tagcagcggc
     7501 attctgccgg tgatcaacac cgccatcgcc cataaagatg cgggcgtcgg catgattggc
     7561 gcgggcattg tgcatccacc ttttgcctgc ttcgagaaag ccattcttgg ctggtgcgaa
     7621 cgttacggcg tctgacctac atgttcatgc cggatgcggc gtgaacgcct tatccggcct
     7681 acgaatggcg caagaatctg taggcctgat aagcgtagcg catcaggcat ttgtcaccat
     7741 tgccggatgc ggcgtgaacg ccttatccgg cctacgaatg gcgcaagaat ctgtaggcct
     7801 gataagcgta gcgcatcagg catttgccac cactgccgga tgcggcgtgg acgccttatc
     7861 cggcctacga gtggcgcgag aatctgtagg cctgataagc gtagcgcatc aggcatttgt
     7921 caccattgcc ggatgcggcg tgaacgcctt atccggccta cgagtggcgc gagaattgta
     7981 ggcctgataa gcgtagcgca tcaggcagtc tggcgttggt cataacccca tcaccctctg
     8041 tagcggacat aacaacatga aagagcttgt ggtcgttgcc attggtggca acagcattat
     8101 caaagataac gccagccagt cgattgagca tcaggcggag gcggtgaaag ccgtcgccga
     8161 tacggtgctg gaaatgctgg cttccgatta cgacattgtg ctgacccacg gcaacgggcc
     8221 gcaggtcggg ctggatttac gccgtgcgga gattgcccac gagcgcgaag ggctgccctt
     8281 aacgccgctg gcgaactgtg tggcagatac gcagggcggc atcggctatc tgatccaaca
     8341 ggcgctgaat aaccggctgg cgcgtcacgg cgagaagaaa gccgtcaccg tggtgactca
     8401 ggtggaagtg gataaaaacg atccaggttt tgcccatccc accaagccca tcggcgcatt
     8461 ctttagtgac agccagcgtg acgaattaca aaaggcaaac cctgactggt gttttgttga
     8521 agatgccggg cggggctatc gccgcgtggt cgcctcgccg gaaccgaaac gtattgtcga
     8581 agcacctgcc attaaagcgc tgatccaaca aggttttgtc gtaattggcg cgggcggcgg
     8641 tggaattccg gtagtgcgta ctgacgcggg agattaccaa agcgtggacg cggttatcga
     8701 caaagatctc tctaccgcgc tgctggcccg tgaaattcac gccgacattc ttgtgatcac
     8761 cactggcgtc gaaaaagtgt gtattcactt tggcaaaccg cagcagcagg cgctcgatcg
     8821 ggtggatatt gccaccatga cccgctatat gcaggaaggg catttcccgc ccggcagcat
     8881 gttgccaaaa atcatcgcca gcctgacatt tttagaacaa ggcggcaaag aagtgattat
     8941 caccacgccg gaatgcctgc ctgcggcgct gcgcggcgaa acgggcactc atattattaa
     9001 aacgtaagga cgtaagatga aagaaagcaa tagccgccgt gaatttctga gccagagcgg
     9061 taagatggtc accgccgccg cgctgtttgg tacctctgtg ccgctcgccc atgcggcggt
     9121 agctggcacc ctaaactgcg aagcgaacaa caccatgaaa atcactgacc cgcattacta
     9181 tctcgataac gtgctgctgg aaaccggttt tgactacgaa aatggcgtgg cggtgcagac
     9241 ccgcacggcg cgccagaccg tggagattca ggacggcaaa attgtcgccc tgcgcgagaa
     9301 caagctgcat ccggacgcca cgctgccgca ctatgacact ggcggtaagc tgatgctgcc
     9361 caccacccgc gacatgcata ttcatctcga caaaaccttt tacggcgggc cgtggcgctc
     9421 gctcaatcgt ccggcaggca ccaccatcca ggacatgatc aaactcgagc agaaaatgct
     9481 gccggaactg caaccgtaca ctcaggagcg ggcagaaaaa ctgattgatt tattgcagtc
     9541 gaaaggcacc accattgccc gcagccactg caatatcgaa ccggtttccg gcctgaaaaa
     9601 tctgcaaaat ttgcaggcgg tgctggcgcg acgtcaggcg ggctttgagt gtgaaatcgt
     9661 cgccttcccg cagcacggtt tgctgctgtc gaaatctgaa cctttaatgc gtgaagcgat
     9721 gcaggcgggg gcgcattacg tcggcggcct ggacccgacc agtgttgatg gcgcgatgga
     9781 aaaatccctc gacaccatgt tccagattgc gctggactac gacaaaggcg tcgatattca
     9841 cctgcacgaa accactccgg caggcgtggc agccatcaat tatatggttg aaacggtaga
     9901 gaaaacgcca cagctgaagg gcaagctgac catcagtcac gcctttgcgc tggcaacgct
     9961 caacgagcaa caggtagatg aactggcgaa ccggatggtg gtgcaacaaa tttctatcgc
    10021 ctcgacggtg ccgattggca cgctgcatat gccgctcaaa cagttgcacg acaaaggcgt
    10081 aaaagtgatg actggcactg acagcgttat cgaccactgg tcgccttatg gtctgggcga
    10141 catgctggaa aaagccaatc tgtacgcgca gctctatatt cgtcctaacg aacagaacct
    10201 ctcccgctcg ctgtttttag ccactggcga tgtattgccg ctgaatgaaa aaggcgagcg
    10261 tgtatggcca aaagcgcagg atgacgccag ctttgtgctg gtggacgcct cctgttccgc
    10321 cgaggcggtg gcgcgtatct cgccgagaac cgcaacgttc cataaagggc aactggtgtg
    10381 ggggagtgtg gcaggttgat gcgcatttga aacgcctgca acggtgaata gtaagagatt
    10441 taagccccag ggagtggggc aatctgaata tgagtgtgtc ggcagaaatg gacattatct
    10501 ttgaggaata tgcccttatt gacgttgtgt agataactat ttgtctacgt gaaaagatca
    10561 tcagttttgc cgattttagt cttttacaga tagcaaatat cacacttaca ggcgctcgcc
    10621 ttatggggaa cgttgctgct ctgtttcatt caggctcgcg gcatgttggg gctggatcgg
    10681 gtggtttaaa tattggctat attcaatgga cgcgttttgc cgcgatgaca tatcaggcgt
    10741 tgccaaatac acatagctaa tcaggagtaa acacaatgaa gatcaaagct gttggtgcat
    10801 attccgctaa acaaccactt gaaccgatgg atatcacccg gcgtgaaccg ggaccgaatg
    10861 atgtcaaaat cgaaatcgct tactgtggcg tttgccattc cgatctccac caggtccgtt
    10921 ccgagtgggc ggggacggtt tacccctgcg tgccgggtca tgaaattgtg gggcgtgtgg
    10981 tagccgttgg tgatcaggta gaaaaatatg cgccgggcga tctggtcggt gtcggctgca
    11041 ttgtcgacag ttgtaaacat tgcgaagagt gtgaagacgg gttggaaaac tactgtgatc
    11101 acatgaccgg cacctataac tcgccgacgc cggacgaacc gggccatact ctgggcggct
    11161 actcacaaca gatcgtcgtt catgagcgat atgttctgcg tattcgtcac ccgcaagagc
    11221 agctggcggc ggtggctcct ttgttgtgtg cagggatcac cacgtattcg ccgctacgtc
    11281 actggcaggc cgggccgggt aaaaaaatgg gcgtggtcgg catcggcggt ctgggacata
    11341 tggggattaa gctggcccac gcgatggggg cacatgtggt ggcatttacc acttctgagg
    11401 caaaacgcga agcggcaaaa gccctggggg ccgatgaagt tgttaactca cgcaatgccg
    11461 atgagatggc ggctcatctg aagagtttcg atttcatttt gaatacagta gctgcgccac
    11521 ataatctcga cgattttacc accttgctga agcgtgatgg caccatgacg ctggttggtg
    11581 cgcctgcgac accgcataaa tcgccggaag ttttcaacct gatcatgaaa cgccgtgcga
    11641 tagccggttc tatgattggc ggcattccag aaactcagga gatgctcgat ttttgcgccg
    11701 aacatggcat cgtggctgat atagagatga ttcgggccga tcaaattaat gaagcctatg
    11761 agcgaatgct gcgcggtgat gtgaaatatc gttttgttat cgataatcgc acactaacag
    11821 actgaaaaaa ttaataaata ccctgtggtt taacatatta acttcgctct ccacttaact
    11881 ttttagttaa ggagagcgaa ataatatcaa agtagcagta aaacctataa cgtaaattta
    11941 aattgttaaa ttaacgccct ccagtacaca atacttcaca cgttagttat gagcgatttc
    12001 tgatagtgcc tggtttaatc agagctttat tatctgcgac gtttattttt atttaagaga
    12061 gatcgcgatg atatcattaa aagctccgca caataatttg atgccatata cgcaacaaag
    12121 catacttaat acggttaaaa acaatcagtt accagaggat atcaaaagct ccctggtttc
    12181 ctgtgtcgat atattcaagg ttttgattaa acaatattat gattatcctt atgattgtcg
    12241 tgatgattta gtcgatgacg acaaactcat tcatctcatg gctgccgtac gagactgtga
    12301 gtggtcagac gataacgcac tcaccataaa tgtgcagttt aatgatttcc ctggatttta
    12361 tgactggatg gattaccctg atcacccggt taagtttgtt tttcacatac ttgaaaatca
    12421 aaaagggaca gtttgggtat atgaccagga tgatgcgttt cttgatatta aagcaaacgt
    12481 gcaggctgga cgctttaccg ggcttaagaa attagtgcag tttatcgatt cagtgcgaac
    12541 agattgcaaa tgtattcttc ttgaatacca tatgcctttg ctgagaattt tccctaaagg
    12601 gaaagagtgt atgcatgtgg aaaaatggct tcgcgaaatg tcgtctattc cggagacaga
    12661 cgcgcccatt aagcaggcgc ttgcgcatgg attattatta cacttaaaaa atatctaccc
    12721 tgtttttcct gaatcactgg tgatgttatt gctctctgtt ctggacgtaa aaacatacag
    12781 agatgatgcg cgattaaatg aatggatatc taatagagtg caggaattag gtgacagata
    12841 ttatcctgta aataagcacg ttaaaatccg ctacactctt tagttcagaa agggttccac
    12901 ctgcaagttg ttattccacc tgagagtgaa tcgcaatgca ggtaatcatt tcatctgtat
    12961 atctgtatgc caactggcat tccatctctt ttttcgccga tattttgttg tgatcggcga
    13021 cacttcgctt aaaaaagcac cagtagtggt ttcgcagcca tgcggtgtat aaaaaatgat
    13081 ctcatgcaga tgttttgtga atgtgttggt tgacattcat atgaaaaaaa tcataattcc
    13141 atcatgtttg tgtggggtct tttctgtatc ttacgcatcg cactcaagcc tgacagaaaa
    13201 tatgctgtaa ggctcatatc aaaaaccgcc attagctcat caggaagagc agacgacaac
    13261 caggattgtt gtatggtacg gggttcgagg cctcgatggc ggtccaactt ttcaaaactc
    13321 ttctgaatca gatcccctta ttatcatccc tgcaaagtgg aacattgcca ttgtttggct
    13381 attcaggatg gggcagacca atgaaaaaag cccacacagg ggagagtggg ctgaaatggg
    13441 aagctaaaga ctcaagtaaa cttatcggaa ataaggacca cgcattacgg gggctatcat
    13501 cgccgatggc cgtgattcgg caaatcaggt tgattacgta gagagtaaat tatctgctca
    13561 ccgctgcgtc accccttcgt aaatcaggcg tagcgcgaat acaccaataa ttgcaccaat
    13621 aacccgactg gcaacgcgtt gcatacgccc ataagcacga cgcacagcgg gcaaagaaaa
    13681 cgcctgacta agaaaaactc gccagataat tgatgcgagc acaatccccg cccaggccat
    13741 taaacgtgcc catgttggtg tttcggcatt taatgttact gagaaaatac tgataaaaaa
    13801 taaaacggtt tgcgggttag agagatcggt aattaatccg cggcgaaaaa agacatacca
    13861 gggggcgcta atcggttgtt gtagtgtgct catttgcggt gttgactggc ggcgcatgct
    13921 gcaccacgca aaccataaga gataagcgcc gccgacgatt ctgataagcg aaaaaatctc
    13981 ctcacactgc gtaattagcg ttgcaagacc aaacaaaccc aacccggaat aaaatgcatc
    14041 gcccagcgcc acgcccagcc cggtcagcac ccctgcgcgt cgaccggaag ccaggctggt
    14101 ttgtactacc acaaagagat tggctcccgg attaaaaaaa gtaatcacga acagtcctac
    14161 ggtcaggtaa acggcatgca aaggatccat agtgatttca tccataaata agtgaactaa
    14221 ctgcatcata tttctaccaa aaataatcgg gtgcgagaga gatcacaaag tgtcttattt
    14281 ccggttactg gcgtttatgc cctgactgaa ctaattatta atcaacccaa taatgtgggt
    14341 gggtgatagt gtgataacaa ctctggagcc gtaatatgaa aataatctct aaaatgttag
    14401 tcggtgcgtt agcgttagcc gttaccaatg tctatgccgt tgaattgatg accaaagcgg
    14461 aatttgaaaa agttgaatcg cagtatgaaa aaataggtga tatttcaacc agcaatgaaa
    14521 tgtcgactgc agatgcaaaa gaagatttga tcaaaaaagc ggatgaaaaa ggggctgatg
    14581 tgttggtact gacctccggt caaactgaca ataagatcca cggcacggca aatatttata
    14641 agaagaagta attctgaatc ctatgtaaac atctccgatg cgtaagttta tcggtgatca
    14701 tctattgaaa tttatgccgg ataaagcgtt cgcgctgcat tcggcagttc agcttttcag
    14761 ccgccgccag aacgtcgtcc ggctgatgcc taaataattc gccgctgctg ttttatcgcc
    14821 attaaatttc tccagtgcct gttgtggtgt cagtaagcgt ggagcgggag ttttcgccga
    14881 ctcgcgcgcc agttccggca gtagcagttg cataaactgc ggcgttaaat ccggcgtcgg
    14941 ttccacactt aaaaacagcg ccagtcgttc catcatattg cgcagttcac gaatattgcc
    15001 tggccagtcg tagtgcagca gcacagtttc acttgcctgt aacccctggc gtaatgcagc
    15061 agaaaatggg gcggagagcg ccgccagaga cactttcaaa aagctttccg ccagcggaag
    15121 aatatccgcc acccgctcgc gcagtggtgg caattgcaga cgcaaaatac tcagccgata
    15181 aaacagatca cggcgaaaac gtccttgctg catatcttct tccagattgc agtgagtggc
    15241 gctaatgacc cgtacatcta ccggaacagg ctgatgcccg ccgacgcggg tgacctcttt
    15301 ttcttccagc acccgcagca gccgggtctg caaaggtagc ggcatttcgc caatctcatc
    15361 cagaaacagc gtaccgccgt gggcaatttc gaacagcccg gcgcgacctc cgcgtcgcga
    15421 gccggtaaac gccccttcct catagccaaa cagttctgct tccagcagcg attcggcaat
    15481 cgccccgcag ttgacggcaa caaacggatg cgactttttg ccctgtcgcg catcgtggcg
    15541 ggcaaaatat tcccgatgaa tcgcctgggc cgccagctct ttgcccgtcc ccgtttcccc
    15601 ctcaatcaac accgccgcac tggagcgggc atacagcaaa atagtctgcc gtacttgttc
    15661 catctgtggt gattgaccga gcatatcgcc cagcacgtaa cgagtacgca gggcgttgcg
    15721 ggtggcatcg tgagtgttat ggcgtaacga catgcgcgtc atatccagcg catcgctgaa
    15781 cgcctggcgc acggtggcgg cggaatagat aaaaattccg gtcattccgg cttcttctgc
    15841 caaatcggta atcagccctg cgccgaccac cgcttcggtg ccgttagctt ttagctcgtt
    15901 aatctgcccg cgtgcgtctt cctcggtaat gtagctacgt tggtcgaggc gcaaattaaa
    15961 ggttttttga aacgccacca gcgctggaat ggtttcctga taggtgacaa cgccgataga
    16021 agaggtgagt tttccggctt ttgccagtgc ctgtaacaca tcgtagccgc tcggtttaat
    16081 caaaataact ggcactgaca ggcggctttt caggtacgcg ccgttagagc cagccgcgat
    16141 gatggcgtca cagcgttcgt ttgccagttt cttgcggatg taggtcactg ctttttcaaa
    16201 gccaagctga ataggggtaa tgttcgccag gtgatcaaac tcgaggctga tatcgcgaaa
    16261 cagctcgaac aggcgcgtta cagataccgt ccagataacc ggtttgtcgt cattaagccg
    16321 tggtggatgt gccatagcgc accgcaaagt taagaaaccg aatattgggt ttagtcttgt
    16381 ttcataattg ttgcaatgaa acgcggtgaa acattgcctg aaacgttaac tgaaacgcat
    16441 atttgcggat tagttcatga ctttatctct aacaaattga aattaaacat ttaattttat
    16501 taaggcaatt gtggcacacc ccttgctttg tctttatcaa cgcaaataac aagttgataa
    16561 caaaggatgg gctatgtctc tacactctcc aggtaaagcg tttcgcgctg cactgactaa
    16621 agaaaatcca ttgcagattg ttggcaccat caacgctaat catgcgctgt tggcgcagcg
    16681 tgccggatat caggcaattt atctttctgg cggtggcgtg gcggcaggtt cgctggggct
    16741 gcccgatctc ggtatttcta cccttgatga tgtgctgacc gacattcgcc gtatcaccga
    16801 cgtttgttcg ctgccgctgc tggtggatgc ggatatcggt tttggttctt cggcctttaa
    16861 cgtggcgcgc accgtgaaat cgatgattaa agccggtgcg gcaggattgc atattgaaga
    16921 tcaggttggt gcgaaacgct gcggtcatcg tccgaataaa gcgatcgtct cgaaagaaga
    16981 gatggtggat cggatccgcg cggcggtgga tgcgaaaacc gatcctgatt ttgtgatcat
    17041 ggcgcgcacc gatgctctgg cggtagaggg gctggatgcg gcgatcgagc gtgcgcaggc
    17101 ctatgttgaa gcgggtgccg agatgttgtt cccggaggcg attaccgaac tcgccatgta
    17161 ccgccagttt gccgatgcgg tgcaggtgcc gatcctcgcc aacatcaccg aatttggtgc
    17221 cacgccgctg tttaccaccg acgaattacg cagcgcccat gtcgcaatgg cgctgtaccc
    17281 actttcagcg ttccgcgcca tgaaccgcgc cgctgaacat gtctacaacg tcctgcgcca
    17341 ggaaggcacg cagaaaagcg tcatcgacac catgcagacc cgcaacgagc tgtacgaaag
    17401 catcaactac taccagtacg aagagaagct cgacaacctg tttgcccgta gccaggtgaa
    17461 ataaaaaacg cccgttgatt gtattcgaca gccgatgcct gatgcgtcgc tgacgcgact
    17521 tatcaggcct acgaggtgca ctgaactgta ggtcggataa gacggatggc gtcgcatccg
    17581 acaaccgatg cctgatgcgc cgctgacgtg acttatcagg cctacggggt gcactgaact
    17641 gtaggtcgga taagacgcat agcgtcgcat ccgacaaccg atgcctgatg cgccgctgac
    17701 gcgacttatc aggcctacgg ggtgcactga actgtaggtc ggataagacg catagcgtcg
    17761 catccgacaa ccgatgcctg atgcgccgct gacgcgactt atcaggccta cggggtgaac
    17821 tgaactgtag gtcggataag acgcatagcg tcgcatccga caacaatctc gaccctacaa
    17881 atgataacaa tgacgaggac aacatgagcg acacaacgat cctgcaaaac agtacccatg
    17941 tcattaaacc gaaaaaatct gtggcacttt ctggcgttcc ggcgggcaat acggcgctct
    18001 gcaccgtggg taaaagtggc aatgacctgc attaccgcgg ctacgatatt cttgatctgg
    18061 cgaaacattg cgaatttgaa gaagtggcgc atctgctgat ccacggcaaa ctgccgaccc
    18121 gtgacgaact cgccgcttac aaaacgaaac tgaaagccct gcgcggttta ccggctaacg
    18181 tgcgtaccgt gctggaagcc ttaccggcgg cgtcgcaccc gatggatgtt atgcgcaccg
    18241 gtgtttccgc gctcggctgc acgctgccag aaaaagaggg gcataccgtc tctggcgcgc
    18301 gggatattgc cgacaaactg ctggcgtcgc ttagctcgat tctcctttat tggtatcact
    18361 acagccacaa cggcgaacgc atccaaccgg aaaccgatga cgactccatc ggcggtcact
    18421 tcctgcatct gctgcacggc gaaaagccat cgcaaagctg ggaaaaggcg atgcatatct
    18481 cgctggtgct gtacgccgaa cacgagttta acgcctccac ctttaccagt cgggtgattg
    18541 cgggcaccgg ctctgatatg tattccgcga ttattggcgc gattggcgca ctgcgcgggc
    18601 caaaacacgg cggggcgaat gaagtgtcgc tggagatcca gcaacgctac gaaacgccgg
    18661 acgaagccga agcagatatc cgcaagcgcg tggaaaacaa agaagtggtc attggttttg
    18721 gtcatccggt ttacaccatc gctgacccgc gccaccaggt gattaaacgt gtggcgaagc
    18781 agctctcgca ggaaggcggc tcgctgaaga tgtacaacat cgccgatcgc ctggaaacgg
    18841 tgatgtggga gagcaaaaag atgttcccca atctcgactg gttctctgct gtttcctaca
    18901 acatgatggg cgttcccacc gagatgttca caccactgtt tgttatcgcc cgcgtcaccg
    18961 gctgggcggc gcacattatc gaacaacgtc aggacaacaa aattatccgt ccttccgcca
    19021 attatgttgg accggaagac cgcccgtttg tcgcgctgga taagcgccag taaacctcta
    19081 cgaataacaa taaggaaacg tacccaatgt cagctcaaat caacaacatc cgcccggaat
    19141 ttgatcgtga aatcgttgat atcgtcgatt acgtcatgaa ctacgaaatc agctctaaag
    19201 tggcctacga caccgcacat tactgcctgc tcgacacgct cggctgcggt ctggaagctc
    19261 tcgaataccc ggcctgtaaa aaactgctgg ggccaattgt tcccggcacc gtcgtaccca
    19321 acggcgtgcg cgtccccgga actcagttcc agctcgaccc cgtccaggcg gcatttaaca
    19381 tcggcgcgat gatccgctgg ctcgatttca acgatacctg gctggcggcg gagtggggcc
    19441 atccttccga caacctcggc ggcattctgg caacggcgga ctggctttcg cgcaacgcgg
    19501 tcgccagcgg caaagcgccg ttgaccatga aacaggtgct gaccgcaatg atcaaagccc
    19561 atgaaattca gggctgcatc gcgctggaaa actcctttaa ccgcgtcggc ctcgaccacg
    19621 ttctgttagt gaaagtggct tccaccgccg tggtcgccga aatgctcggc ctgacccgcg
    19681 aggaaattct caacgccgtt tcgctggcgt gggtggacgg tcagtcgctg cgcacctatc
    19741 gccatgcgcc gaacaccggc acgcgtaaat cctgggcggc gggcgatgcc acttcccgcg
    19801 cggtacgtct ggcactgatg gcgaaaacgg gcgaaatggg ttacccgtca gccctgactg
    19861 cgccggtgtg gggcttctac gacgtctcct ttaaaggtga atcgttccgc ttccagcgcc
    19921 cgtacggttc ctacgttatg gaaaatgtgc tgttcaaaat ctccttcccg gcggagttcc
    19981 actcccagac ggcagttgaa gcagcgatga cgctctatga acagatgcag gcagcaggca
    20041 aaacggcggc ggatatcgaa aaagtgacca ttcgcaccca cgaagcctgt attcgcatca
    20101 tcgacaaaaa agggccgctc aataacccgg cagaccgcga tcactgcatt cagtacatgg
    20161 tggcgatccc gctgctattc gggcgcttaa cggcggcaga ttacgaggac aacgttgcgc
    20221 aagataaacg cattgacgcc ctgcgcgaga agatcaattg ctttgaagat ccggcattta
    20281 ccgctgacta ccacgacccg gaaaaacgcg ccatcgccaa tgccattacc cttgagttca
    20341 ccgacggcac acgatttgaa gaagtggtgg tggagtaccc cattggtcat gctcgccgcc
    20401 gtcaggatgg tattccgaaa ctggtcgata aattcaaaat caatctcgcg cgccagttcc
    20461 cgactcgcca acagcagcgc attctggagg tttctctcga cagagctcgc ctggaacaga
    20521 tgccggtcaa tgagtatctc gacctgtacg tcatttaagt aaacggcggt aaggcgtaag
    20581 ttcaacagga gagcattatg tcttttagcg aattttatca gcgttcgatt aacgaaccgg
    20641 agcagttctg ggccgagcag gcccggcgta ttgactggca gacgcccttt acgcaaacgc
    20701 tcgatcacag caatccgccg tttgcccgtt ggttttgtga aggccgaacc aacttgtgcc
    20761 acaacgccat cgaccgctgg ctggagaaac agccagaggc gctggcgctg attgccgtct
    20821 cttcggaaac agaagaagag cgcaccttta cctttcgtca gctgcatgac gaagtgaacg
    20881 cggtggcctc aatgttgcgt tcattgggtg tgcagcgcgg cgatcgggtg ctggtgtata
    20941 tgccgatgat tgccgaagcg catattactc tgctggcctg cgcgcgcatt ggcgctattc
    21001 actcggtggt gtttggtgga tttgcctcgc acagcgtggc ggcgcgaatt gatgacgcta
    21061 aaccggtgct gattgtctcg gctgatgccg gagcgcgcgg tggcaaaatc attccctata
    21121 aaaaattgct cgacgatgcg ataagtcagg cgcagcacca gccacgccat gttttgctgg
    21181 tggatcgcgg gctggcgaaa atggcgcgcg tcagcgggcg ggatgtcgat ttcgcgtcgt
    21241 tgcgccatca acacatcggc gcgcgggtac cggtggcgtg gctggaatcc aacgaaacct
    21301 cctgcattct ctacacttcc ggcacgaccg gcaaacctaa aggcgtgcag cgtgacgtcg
    21361 gcggatatgc ggtggcgctg gcgacctcga tggacaccat ttttggcggc aaagcgggca
    21421 gcgtgttctt ttgcgcatcg gatatcggct gggtggtggg gcattcgtat atcgtttacg
    21481 cgccgctgct ggcggggatg gcgactatcg tttacgaagg attgccgacc tggccggact
    21541 gcggcgtgtg gtggaaaatc gtcgagaaat atcaggttag ccggatgttc tcagcgccga
    21601 ccgccattcg cgtgctgaaa aaattcccta ccgctgaaat tcgcaaacac gatctctcgt
    21661 cgctggaagt gctctatctg gctggagaac cgctggacga gccgaccgcc agttgggtga
    21721 gcaatacgct ggatgtgccg gtcatcgaca actactggca gaccgaatcc ggctggccga
    21781 ttatggcgat tgctcgcggt ctggacgaca ggccgacgcg tctgggaagc cccggtgtgc
    21841 cgatgtatgg ctataacgtg cagttgctta atgaagtcac cggcgaaccg tgtggcgtca
    21901 acgagaaagg gatgctggtg gtggaagggc cgctgccgcc ggggtgtatt cagaccatct
    21961 ggggcgacga cggccgcttt gtgaagactt actggtcgct gttttcccgc ccggtgtacg
    22021 ccacctttga ctggggcatc cgtgacgctg acggttatca ctttattctc gggcgcactg
    22081 acgatgtaat taacgttgcc gggcatcggc tggggacgcg cgagattgaa gagagtatct
    22141 ccagccatcc gggcgttgcc gaagtggcgg tggttggggt gaaagatgcg ctgaaagggc
    22201 aggtggcggt ggcgtttgtc attccgaaag agagcgacag tctggaagat cgtgatgtgg
    22261 cgcactcgca agagaaggcg attatggcgc tggtggacag ccagattggc aactttggcc
    22321 gcccggcgca cgtctggttt gtcttgcaat tgccaaaaac gcgatccgga aaaatgctgc
    22381 gccgcacgat ccaggcgatt tgcgaaggac gcgatcctgg agatctgacg accattgatg
    22441 atcctgcgtc gttggatcag atccgccagg cgatggaaga gtaggttatt gtcggatgcg
    22501 tcgcgcggtg catccggcac tgtgtgccga tgcctgatgc gacgctgacg cgttttatca
    22561 tgcctacgga cctgaaccgt aggtcggata aggcgctcgc gtcgcatccg acaccatgct
    22621 cagatgcctg atgcgacgct gacgcgtctt atcaggccta cccactgttt ttacaccgat
    22681 aatttttccc ccaccttttt gcactcattc atataaaaaa tatatttccc cacgaaaacg
    22741 attgcttttt atcttcagat gaatagaatg cggcggattt tttgggtttc aaacagcaaa
    22801 aagggggaat ttcgtgtcgc aagataacaa ctttagccag gggccagtcc cgcagtcggc
    22861 gcggaaaggg gtattggcat tgacgttcgt catgctggga ttaaccttct tttccgccag
    22921 tatgtggacc ggcggcactc tcggaaccgg tcttagctat catgatttct tcctcgcagt
    22981 tctcatcggt aatcttctcc tcggtattta cacttcattt ctcggttaca ttggcgcaaa
    23041 aaccggcctg accactcatc ttcttgctcg cttctcgttt ggtgttaaag gctcatggct
    23101 gccttcactg ctactgggcg gaactcaggt tggctggttt ggcgtcggtg tggcgatgtt
    23161 tgccattccg gtgggtaagg caaccgggct ggatattaat ttgctgattg ccgtttccgg
    23221 tttactgatg accgtcaccg tcttttttgg catttcggcg ctgacggttc tttcggtgat
    23281 tgcggttccg gctatcgcct gcctgggcgg ttattccgtg tggctggctg ttaacggcat
    23341 gggcggcctg gacgcattaa aagcggtcgt tcccgcacaa ccgttagatt tcaatgtcgc
    23401 gctggcgctg gttgtggggt catttatcag tgcgggtacg ctcaccgctg actttgtccg
    23461 gtttggtcgc aatgccaaac tggcggtgct ggtggcgatg gtggcctttt tcctcggcaa
    23521 ctcgttgatg tttattttcg gtgcagcggg cgctgcggca ctgggcatgg cggatatctc
    23581 tgatgtgatg attgctcagg gcctgctgct gcctgcgatt gtggtgctgg ggctgaatat
    23641 ctggaccacc aacgataacg cactctatgc gtcgggttta ggtttcgcca acattaccgg
    23701 gatgtcgagc aaaacccttt cggtaatcaa cggtattatc ggtacggtct gcgcattatg
    23761 gctgtataac aattttgtcg gctggttgac cttcctttcg gcagctattc ctccagtggg
    23821 tggcgtgatc atcgccgact atctgatgaa ccgtcgccgc tatgagcact ttgcgaccac
    23881 gcgtatgatg agtgtcaatt gggtggcgat tctggcggtc gccttgggga ttgctgcagg
    23941 ccactggtta ccgggaattg ttccggtcaa cgcggtatta ggtggcgcgc tgagctatct
    24001 gatccttaac ccgattttga atcgtaaaac gacagcagca atgacgcatg tggaggctaa
    24061 cagtgtcgaa taacgcttta caaacaatta ttaacgcccg gttaccaggc gaagaggggc
    24121 tgtggcagat tcatctgcag gacggaaaaa tcagcgccat tgatgcgcaa tccggcgtga
    24181 tgcccataac tgaaaacagc ctggatgccg aacaaggttt agttataccg ccgtttgtgg
    24241 agccacatat tcacctggac accacgcaaa ccgccggaca accgaactgg aatcagtccg
    24301 gcacgctgtt tgaaggcatt gaacgctggg ccgagcgcaa agcgttatta acccatgacg
    24361 atgtgaaaca acgcgcatgg caaacgctga aatggcagat tgccaacggc attcagcatg
    24421 tgcgtaccca tgtcgatgtt tcggatgcaa cgctaactgc gctgaaagca atgctggaag
    24481 tgaagcagga agtcgcgccg tggattgatc tgcaaatcgt cgccttccct caggaaggga
    24541 ttttgtcgta tcccaacggt gaagcgttgc tggaagaggc gttacgctta ggggcagatg
    24601 tagtgggggc gattccgcat tttgaattta cccgtgaata cggcgtggag tcgctgcata
    24661 aaaccttcgc cctggcgcaa aaatacgacc gtctcatcga cgttcactgt gatgagatcg
    24721 atgacgagca gtcgcgcttt gtcgaaaccg ttgctgccct ggcgcaccat gaaggcatgg
    24781 gcgcgcgagt caccgccagc cacaccacgg caatgcactc ctataacggg gcgtatacct
    24841 cacgcctgtt ccgcttgctg aaaatgtccg gtattaactt tgtcgccaac ccgctggtca
    24901 atattcatct gcaaggacgt ttcgatacgt atccaaaacg tcgcggcatc acgcgcgtta
    24961 aagagatgct ggagtccggc attaacgtct gctttggtca cgatgatgtc ttcgatccgt
    25021 ggtatccgct gggaacggcg aatatgctgc aagtgctgca tatggggctg catgtttgcc
    25081 agttgatggg ctacgggcag attaacgatg gcctgaattt aatcacccac cacagcgcaa
    25141 ggacgttgaa tttgcaggat tacggcattg ccgccggaaa cagcgccaac ctgattatcc
    25201 tgccggctga aaatgggttt gatgcgctgc gccgtcaggt tccggtacgt tattcggtac
    25261 gtggcggcaa ggtgattgcc agcacacaac cggcacaaac caccgtatat ctggagcagc
    25321 cagaagccat cgattacaaa cgttgaacga ctgggttaca gcgagcttag tttatgccgg
    25381 atgcggcgtg aacgccttat ccggcctacg tagagcactg aactcgtagg cctgataagc
    25441 gtagcgcatc aggcaattcc agccgctgat ctgtgtcagc ggctaccgtg attcattccc
    25501 gccaacaacc gcgcattcct ccaacgccat gtgcaaaaat gccttcgcag cggctgtctg
    25561 ccagctgtag tttatgccgg atgcggcgtg aacgccttat ccggcctacg tagagcactg
    25621 aactcgtagg cctgataagc gtagcgcatc aggcaattcc agccgcagac ctgtgtcagc
    25681 ggctaccgtg attcatttcc gccaacaacc gcgcatttat ccaacgccat gtgcaaaaat
    25741 gccttcgcgg cggctgtctg ccagctattt ttccgccgca acaaaaccgc cgttctctcc
    25801 agtagtggcg gggcaagaga aatagcttta agcccgtcat gttgtgtggc aatcgctgct
    25861 ggtaacaatg tggaaaggga agtgcggcga atcagctcca gaaccgcgct aattgagttc
    25921 gcctcaatga ccacctgtgg atgtagcccc gctttctcgc agtagtggtc aatttgctct
    25981 ctggtggcaa attccgcgct gagcaggacc agtttttcat catgcaagcg actcaacgcc
    26041 acctgttcat ggacggccag cggatgatgt tgcgccacga ctaacgctaa actttctgtc
    26101 agtaaaggaa ttgcctccag ctccggcgaa tgcacaggcg cgaaggcaat cccaacgtcc
    26161 aactcgtcgc ggcaaagcat atcctcgatt ttctcctgcg acatttcctg tagctggagc
    26221 gtgatgctgg gatagcgcgc atagaaatcc gccattaagg ggccgataaa gtagctcgta
    26281 aaggtggggg tgacggcgat acgcagcgat cctcgcgtca gatcggcaac atcatgaatc
    26341 gcccgtttac ccgcccccag ttcctgtaac gcccggctgg cgtactgtcg ccagacttct
    26401 cctgcatcag tgagacgaat cgttcgcccg ctacggtcaa acagcggcac gcctaaactc
    26461 tcctctaact ggcgaatctg ctgggaaagc gcaggttggg agacgtgcaa cgcactggcg
    26521 gcacgggtga agctgccatg ttcagccacg gcaagaaaat aattgatatg tcgagagagc
    26581 attcgcaacc tataagtaaa tccaatggaa ctcatcataa atgagacttt taccttatga
    26641 caatcggcga gtagtctgcc tctcattcca gagacagaca gaggttaacg gtgaaagaga
    26701 ttattgatgg attccttaaa ttccagcgcg aggcatttcc gaagcgggaa gccttgttta
    26761 aacagctggc gacacagcaa agcccgcgca cactttttat ctcctgctcc gacagccgtc
    26821 tggtccctga gctggtgacg caacgtgagc ctggcgatct gttcgttatt cgcaacgcgg
    26881 gcaatatcgt cccttcctac gggccggaac ccggtggcgt ttctgcttcg gtggagtatg
    26941 ccgtcgctgc gcttcgggta tctgacattg tgatttgtgg tcattccaac tgtggcgcga
    27001 tgaccgccat tgccagctgt cagtgcatgg accatatgcc tgccgtctcc cactggctgc
    27061 gttatgccga ttcagcccgc gtcgttaatg aggcgcgccc gcattccgat ttaccgtcaa
    27121 aagctgcggc gatggtacgt gaaaacgtca ttgctcagtt ggctaatttg caaactcatc
    27181 catcggtgcg cctggcgctc gaagaggggc ggatcgccct gcacggctgg gtctacgaca
    27241 ttgaaagcgg cagcatcgca gcttttgacg gcgcaacccg ccagtttgtg ccactggccg
    27301 ctaatcctcg cgtttgtgcc ataccgctac gccaaccgac cgcagcgtaa ccttattttt
    27361 aaaccatcag gagttccacc atgattcagt cacaaattaa ccgcaatatt cgtcttgatc
    27421 ttgccgatgc cattttgctc agcaaagcta aaaaagatct ctcatttgcc gagattgccg
    27481 acggcaccgg tctggcagaa gcctttgtaa ccgcggcttt gctgggtcag caggcgcttc
    27541 ctgccgacgc cgcccgcctg gtcggggcga agctggatct cgacgaagac tccattctac
    27601 tgttgcagat gattccactg cgtggctgca ttgatgaccg tattccaact gacccaacga
    27661 tgtatcgttt ctatgaaatg ttgcaggtgt acggtacaac cctgaaagcg ttggttcatg
    27721 agaaatttgg cgatggcatt attagcgcga ttaacttcaa actcgacgtt aagaaagtgg
    27781 cggatccgga aggtggcgaa cgtgcggtca tcaccttaga tggtaaatat ctgccgacca
    27841 aaccgttctg acagccatgc gcaaccatca aaagacgttc acgatgctgc tggtactggt
    27901 gctgattggt cttaatatgc gaccactgct cacctccgtc gggccactgc taccgcaatt
    27961 gcgccaggcg agcggaatga gctttagcgt ggctgccctg ttgaccgctc tgccggtggt
    28021 taccatgggc gggctggcgc tggccggaag ctggcttcat cagcatgtca gcgaacgtcg
    28081 cagtgtcgcc atcagtctgt tgctgattgc cgtcggtgca ttgatgcgtg agctttaccc
    28141 gcaaagtgcg ctgctgctta gcagcgcact gcttggtggg gtggggatcg gcatcattca
    28201 ggcggtgatg ccttcggtga ttaaacggcg gtttcagcag cgcacgccac tggtgatggg
    28261 gctgtggtcc gcggctctga tgggcggcgg tgggcttggt gccgccataa cgccctggtt
    28321 agttcaacat agcgaaacct ggtatcaaac actcgcctgg tgggcgctgc ctgccgttgt
    28381 tgcgctcttt gcctggtggt ggcaaagcgc ccgcgaggtc gcctcttccc acaagacaac
    28441 aaccactccg gttcgcgtgg tattcactcc ccgcgcgtgg acgctgggtg tttacttcgg
    28501 tctgattaac ggcggttacg ccagcctgat tgcctggtta cccgctttct atattgagat
    28561 tggtgccagc gcgcagtaca gcggttcctt actggcattg atgacgcttg ggcaagccgc
    28621 aggagctttg ctgatgcctg ctatggctcg ccatcaggat cggcgcaaac tgttaatgct
    28681 ggcgctggtg ttacaactgg tggggttctg cggctttatc tggctgccga tgcaattgcc
    28741 ggtattgtgg gcgatggtgt gtgggttagg tctgggcggc gcgtttccgc tctgtttgct
    28801 gctggcgctc gatcactctg tgcaaccggc tattgctggc aagctggtgg cgtttatgca
    28861 gggaatcggt tttatcatcg ccgggcttgc cccgtggttt tctggcgtgc tgcgtagtat
    28921 cagcggcaat tacctgatgg actgggcatt tcatgcgctg tgcgtcgttg ggctgatgat
    28981 cataaccctg cgttttgcac cagtacgttt tccgcagctg tgggtcaaag aggcatgatg
    29041 cgacgcttgt tcctgcgctt tgttcatgcc ggatgcggct aatgtagatc gctgaacttg
    29101 taggcctgat aagcgcagcg tatcaggcaa tttttataat ttaaactgac gattcaactt
    29161 tataatcttt gaaataatag tgcttatccc ggtcgtttat ttcgcgaata acccgacaag
    29221 gaacgccagc cgccacgacg tttggtggaa tgtcttttgt gacgatacta cccgcgccaa
    29281 taacagaatt atccccgatg gtgacgcctg gattaataac cacatgactt ccgatccaga
    29341 cgttattgcc aatcgttatc ggaaaagagt acatctcgcc gttttttctc aattcatggt
    29401 gtacagggtg tcccgtaacg gaaagagtaa cgttgggtgc aatcagtacg ttatcaccga
    29461 ttgttaccgt gtagtcatcg acaatggtta aattgaaatt tgcataaaaa ttgcggccta
    29521 tatggatgtt ggaaccgtaa gagaaataga caggcggttc tacccaggcg ttttccccta
    29581 ccgtggcaaa catttcttta atcaggcttt ctcttttttc aacttctgat ggatgcgagt
    29641 gattaaactc atacattaac gttttcccac gaagtctttt ttccggtaag ccttcgcaca
    29701 tatcggtaaa tagcttgcct gctcttattc tttcggtcat tggcatgttc aatgcgatca
    29761 ctccgttatg atatgttggt cggataaggc gctcgcgccg catccgacat tgattgctta
    29821 agcgacttca ttcacctgac gacgcagcag ggaaagcggg ccggggccgc taagcgtgaa
    29881 cacggaaatt aaggtgaagc ccagcgccac cagacccagc accagataag cgccctggaa
    29941 accgatgctt tcatacatat tgcccgccag tacagacata aaaatcatcg ccagttgctt
    30001 aaagaagcag aaacagacca gataaatcgt cgctgaaaaa cgcacttcaa actggctggt
    30061 aatatattta aagcagccca ccagcaggaa cggtacttca aacatatgca gcgttttcag
    30121 aataaccact tccagcgctg aggtggcgaa cgatgagcca ataatacgta cagacataat
    30181 agtgccagcc agcagcaggg cgtttttccc accgatgcga ttaatgatca gtggcgcaaa
    30241 gaacataatc gaggcgttaa gtaattcgcc cattgtcgtt acgtagccaa atacccgcgt
    30301 accctgttca ccggtagcaa agaacgaagt aaagaaatta gcaaactgtt ggtcaaaaac
    30361 atcgtaggtg caggaaacgc caataacata cagtgacaaa aaccacagtt ttggctgtct
    30421 gaacagttcc agtgccagct taaggctaaa tgccgaatgg ttggcaccta ccgcattggc
    30481 aaccgtggca gaagagggcg catccgtttt ggcgaaaaag agtaaaacgg cgaggatgag
    30541 tgcacagcca gagcccagcc agaaaacaaa ctgattattg atggtgaaca tgatgccgac
    30601 aatcgaggca cacagcgccc agccaacaca gccaaacatc cgcgcgcgac caaattcgaa
    30661 attactgcga cggctgactt tctcaataaa tgcctctact gctggcgcac cggcgttaaa
    30721 acaaaagcct agataaatac caccaacaat cgatcctact aaaatgttgt attgtaacag
    30781 tggcccgaag ataaaaataa agaacggcgc aaacatcact aacatgccgg taataatcca
    30841 cagcaggtat ttgcgcagcc cgagtttgtc agaaagcaga ccaaacagcg gttggaataa
    30901 tagcgagaac agagaaatag cggcaaaaat aatacccgta tcacttttgc tgatatggtt
    30961 gatgtcatgt agccaaatcg ggaaaaacgg gaagtaggct cccatgataa aaaagtaaaa
    31021 gaaaaagaat aaaccgaaca tccaaaagtt tgtgtttttt aaatagtaca taatggattt
    31081 ccttacgcga aatacgggca gacatggcct gcccggttat tattattttt gacaccagac
    31141 caactggtaa tggtagcgac cggcgctcag ctggaattcc gccgatactg acgggctcca
    31201 ggagtcgtcg ccaccaatcc ccatatggaa accgtcgata ttcagccatg tgccttcttc
    31261 cgcgtgcagc agatggcgat ggctggtttc catcagttgc tgttgactgt agcggctgat
    31321 gttgaactgg aagtcgccgc gccactggtg tgggccataa ttcaattcgc gcgtcccgca
    31381 gcgcagaccg ttttcgctcg ggaagacgta cggggtatac atgtctgaca atggcagatc
    31441 ccagcggtca aaacaggcgg cagtaaggcg gtcgggatag ttttcttgcg gccctaatcc
    31501 gagccagttt acccgctctg ctacctgcgc cagctggcag ttcaggccaa tccgcgccgg
    31561 atgcggtgta tcgctcgcca cttcaacatc aacggtaatc gccatttgac cactaccatc
    31621 aatccggtag gttttccggc tgataaataa ggttttcccc tgatgctgcc acgcgtgagc
    31681 ggtcgtaatc agcaccgcat cagcaagtgt atctgccgtg cactgcaaca acgctgcttc
    31741 ggcctggtaa tggcccgccg ccttccagcg ttcgacccag gcgttagggt caatgcgggt
    31801 cgcttcactt acgccaatgt cgttatccag cggtgcacgg gtgaactgat cgcgcagcgg
    31861 cgtcagcagt tgttttttat cgccaatcca catctgtgaa agaaagcctg actggcggtt
    31921 aaattgccaa cgcttattac ccagctcgat gcaaaaatcc atttcgctgg tggtcagatg
    31981 cgggatggcg tgggacgcgg cggggagcgt cacactgagg ttttccgcca gacgccactg
    32041 ctgccaggcg ctgatgtgcc cggcttctga ccatgcggtc gcgttcggtt gcactacgcg
    32101 tactgtgagc cagagttgcc cggcgctctc cggctgcggt agttcaggca gttcaatcaa
    32161 ctgtttacct tgtggagcga catccagagg cacttcaccg cttgccagcg gcttaccatc
    32221 cagcgccacc atccagtgca ggagctcgtt atcgctatga cggaacaggt attcgctggt
    32281 cacttcgatg gtttgcccgg ataaacggaa ctggaaaaac tgctgctggt gttttgcttc
    32341 cgtcagcgct ggatgcggcg tgcggtcggc aaagaccaga ccgttcatac agaactggcg
    32401 atcgttcggc gtatcgccaa aatcaccgcc gtaagccgac cacgggttgc cgttttcatc
    32461 atatttaatc agcgactgat ccacccagtc ccagacgaag ccgccctgta aacggggata
    32521 ctgacgaaac gcctgccagt atttagcgaa accgccaaga ctgttaccca tcgcgtgggc
    32581 gtattcgcaa aggatcagcg ggcgcgtctc tccaggtagc gaaagccatt ttttgatgga
    32641 ccatttcggc acagccggga agggctggtc ttcatccacg cgcgcgtaca tcgggcaaat
    32701 aatatcggtg gccgtggtgt cggctccgcc gccttcatac tgcaccgggc gggaaggatc
    32761 gacagatttg atccagcgat acagcgcgtc gtgattagcg ccgtggcctg attcattccc
    32821 cagcgaccag atgatcacac tcgggtgatt acgatcgcgc tgcaccattc gcgttacgcg
    32881 ttcgctcatc gccggtagcc agcgcggatc atcggtcaga cgattcattg gcaccatgcc
    32941 gtgggtttca atattggctt catccaccac atacaggccg tagcggtcgc acagcgtgta
    33001 ccacagcgga tggttcggat aatgcgaaca gcgcacggcg ttaaagttgt tctgcttcat
    33061 cagcaggata tcctgcacca tcgtctgctc atccatgacc tgaccatgca gaggatgatg
    33121 ctcgtgacgg ttaacgcctc gaatcagcaa cggcttgccg ttcagcagca gcagaccatt
    33181 ttcaatccgc acctcgcgga aaccgacatc gcaggcttct gcttcaatca gcgtgccgtc
    33241 ggcggtgtgc agttcaacca ccgcacgata gagattcggg atttcggcgc tccacagttt
    33301 cgggttttcg acgttcagac gtagtgtgac gcgatcggca taaccaccac gctcatcgat
    33361 aatttcaccg ccgaaaggcg cggtgccgct ggcgacctgc gtttcaccct gccataaaga
    33421 aactgttacc cgtaggtagt cacgcaactc gccgcacatc tgaacttcag cctccagtac
    33481 agcgcggctg aaatcatcat taaagcgagt ggcaacatgg aaatcgctga tttgtgtagt
    33541 cggtttatgc agcaacgaga cgtcacggaa aatgccgctc atccgccaca tatcctgatc
    33601 ttccagataa ctgccgtcac tccagcgcag caccatcacc gcgaggcggt tttctccggc
    33661 gcgtaaaaat gcgctcaggt caaattcaga cggcaaacga ctgtcctggc cgtaaccgac
    33721 ccagcgcccg ttgcaccaca gatgaaacgc cgagttaacg ccatcaaaaa taattcgcgt
    33781 ctggccttcc tgtagccagc tttcatcaac attaaatgtg agcgagtaac aacccgtcgg
    33841 attctccgtg ggaacaaacg gcggattgac cgtaatggga taggtcacgt tggtgtagat
    33901 gggcgcatcg taaccgtgca tctgccagtt tgaggggacg acgacagtat cggcctcagg
    33961 aagatcgcac tccagccagc tttccggcac cgcttctggt gccggaaacc aggcaaagcg
    34021 ccattcgcca ttcaggctgc gcaactgttg ggaagggcga tcggtgcggg cctcttcgct
    34081 attacgccag ctggcgaaag ggggatgtgc tgcaaggcga ttaagttggg taacgccagg
    34141 gttttcccag tcacgacgtt gtaaaacgac ggccagtgaa tccgtaatca tggtcatagc
    34201 tgtttcctgt gtgaaattgt tatccgctca caatttcaca caacatacga gccggaagca
    34261 taaagtgtaa agcctggggt gcctaatgag tgagctaact cacattaatt gcgttgcgct
    34321 cactgcccgc tttccagtcg ggaaacctgt cgtgccagct gcattaatga atcggccaac
    34381 gcgcggggag aggcggtttg cgtattgggc gccagggtgg tttttctttt caccagtgag
    34441 acgggcaaca gctgattgcc cttcaccgcc tggccctgag agagttgcag caagcggtcc
    34501 acgctggttt gccccagcag gcgaaaatcc tgtttgatgg tggttaacgg cgggatataa
    34561 catgagctgt cttcggtatc gtcgtatccc actaccgaga tatccgcacc aacgcgcagc
    34621 ccggactcgg taatggcgcg cattgcgccc agcgccatct gatcgttggc aaccagcatc
    34681 gcagtgggaa cgatgccctc attcagcatt tgcatggttt gttgaaaacc ggacatggca
    34741 ctccagtcgc cttcccgttc cgctatcggc tgaatttgat tgcgagtgag atatttatgc
    34801 cagccagcca gacgcagacg cgccgagaca gaacttaatg ggcccgctaa cagcgcgatt
    34861 tgctggtgac ccaatgcgac cagatgctcc acgcccagtc gcgtaccgtc ttcatgggag
    34921 aaaataatac tgttgatggg tgtctggtca gagacatcaa gaaataacgc cggaacatta
    34981 gtgcaggcag cttccacagc aatggcatcc tggtcatcca gcggatagtt aatgatcagc
    35041 ccactgacgc gttgcgcgag aagattgtgc accgccgctt tacaggcttc gacgccgctt
    35101 cgttctacca tcgacaccac cacgctggca cccagttgat cggcgcgaga tttaatcgcc
    35161 gcgacaattt gcgacggcgc gtgcagggcc agactggagg tggcaacgcc aatcagcaac
    35221 gactgtttgc ccgccagttg ttgtgccacg cggttgggaa tgtaattcag ctccgccatc
    35281 gccgcttcca ctttttcccg cgttttcgca gaaacgtggc tggcctggtt caccacgcgg
    35341 gaaacggtct gataagagac accggcatac tctgcgacat cgtataacgt tactggtttc
    35401 acattcacca ccctgaattg actctcttcc gggcgctatc atgccatacc gcgaaaggtt
    35461 ttgcgccatt cgatggtgtc aacgtaaatg catgccgctt cgccttccgg ccaccagaat
    35521 agcctgcgat tcaacccctt cttcgatctg ttttgctacc cgttgtagcg ccggaagatg
    35581 cttttccgct gcctgttcaa tggtcattgc gctcgccata tacaccagat tcagacagcc
    35641 aatcacccgt tgttcactgc gcagcggtac ggcgatagag gcgatcttct cctcctgatc
    35701 ccagccgcgg tagttctgtc cgtaaccctc tttgcgcgcg cgcgccagaa tggcttccag
    35761 ctttaacggt tcccgtgcca gttgatagtc atcaccgggg cgggaggcta acatttcgat
    35821 taattccttg cggtcttgtt ccgggcaaaa ggccagccag gtcaggcccg aggcggtttt
    35881 cagaagcggc aaacgtcgcc cgaccattgc ccggtgaaag gataagcggc tgaaacggtg
    35941 agtggtttcg cgtaccacca ttgcatcaac atccagcgtg gacacatctg tcggccatac
    36001 cacttcgcgc aacagatcgc ccagcagtgg ggccgccagt gcagaaatcc actgttcgtc
    36061 acgaaatcct tcgcttaatt gccgcacttt gatggtcagt cgaaaactat catcggaggg
    36121 gctacggcgg acatatccct cttcctgcag cgtctccagc agtcgccgca cagtggtgcg
    36181 atgcaggccg ctgagttccg ccagcagccc gacgctggca ccgccatcaa gtttatttaa
    36241 catatttaat aacattagac cgcgggttaa gccgcgcacg gttttgtatt ccgtctgctc
    36301 attgttctgc atattaattg acatttctat agttaaaaca acgtggtgca cctggtgcac
    36361 attcgggcat gttttgattg tagccgaaaa cacccttcct atactgagcg cacaataaaa
    36421 aatcatttac atgtttttaa caaaataagt tgcgctgtac tgtgcgcgca acgacatttt
    36481 gtccgagtcg tgaggtactg aaatggcaat acaacaccct gacatccagc ctgctgttaa
    36541 ccatagcgtt caggtggcga tcgctggtgc cggcccggtt gggctgatga tggcgaacta
    36601 tctcggccag atgggcattg acgtgctggt ggtggagaaa ctcgataagt tgatcgacta
    36661 cccgcgtgcg attggtattg atgacgaggc gctgcgcacc atgcagtcgg tcggcctggt
    36721 cgatgatgtt ctgccgcaca ctacgccgtg gcacgcgatg cgttttctca ccccgaaagg
    36781 ccgctgtttt gctgatattc agccaatgac cgatgaattt ggctggccgc gccgtaacgc
    36841 ctttattcag ccgcaggtcg atgcggtgat gctggaaggg gtgtcgcgtt ttccgaatgt
    36901 gcgctgcttg ttttcccgcg agctggaggc cttcagtcag caagatgacg aagtgacctt
    36961 gcacctgaaa acggcagaag ggcagcggga aatagtcaaa gcccagtggc tggtagcctg
    37021 tgacggtgga gcaagttttg tccgtcgcac tctgaatgtg ccgtttgaag gtaaaactgc
    37081 gccaaatcag tggattgtgg tagatatcgc caacgatccg ttaagtacgc cgcatatcta
    37141 tttgtgttgc gatccggtgc gcccgtatgt ttctgccgcg ctgcctcatg cggtacgtcg
    37201 ctttgaattt atggtgatgc cgggagaaac cgaagagcag ctgcgtgagc cgcaaaatat
    37261 gcgcaagctg ttaagcaaag tgctgcctaa tccggacaat gttgaattga ttcgccagcg
    37321 tgtctacacc cacaacgcgc gactggcgca acgtttccgt attgatcgcg tactgctggc
    37381 gggcgatgcc gcgcacatca tgccggtatg gcaggggcag ggctataaca gtggtatgcg
    37441 cgacgccttt aacctcgcat ggaaactggc gttggttatc caggggaaag cccgcgatgc
    37501 gctgctcgat acctatcaac aagaacgtcg cgatcacgcc aaagcgatga ttgacctgtc
    37561 cgtgacggcg ggcaacgtgc tggctccgcc gaaacgctgg cagggtacgt tacgtgacgg
    37621 cgtttcctgg ctgttgaatt atctgccgcc agtaaaacgc tacttcctcg aaatgcgctt
    37681 caagccgatg ccgcaatatt acggcggtgc gctgatgcgt gagggcgaag cgaagcactc
    37741 tccggtcggc aagatgttta ttcagccgaa agtcacgctg gaaaacggcg acgtgacgct
    37801 gctcgataac gcgatcggcg cgaacttcgc ggtaattggc tggggatgca atccactgtg
    37861 ggggatgagc gacgagcaaa tccagcagtg gcgcgcgttg ggcacacgct tcattcaggt
    37921 ggtgccggaa gtgcaaattc ataccgcaca ggataaccac gacggcgtac tacgcgtggg
    37981 cgatacgcaa ggtcgcctgc gtagctggtt cgcgcaacac aatgcttcgc tggtggtgat
    38041 gcgcccggat cgctttgttg ccgccaccgc cattccgcaa accctgggca agaccctgaa
    38101 taaactggcg tcggtgatga cgctgacccg ccctgatgcc gacgtttctg tcgaaaaggt
    38161 agcctgatat gcacgcttat cttcactgtc tttcccactc gccgctggtg gggtatgtcg
    38221 acccggcgca agaggtgctc gatgaggtca atggcgtgat tgccagcgcc cgcgagcgta
    38281 ttgcggcatt ctcccctgaa ctggtggtgc tgtttgcgcc agatcactac aacggctttt
    38341 tctatgacgt gatgccaccg ttctgtttag gcgttggagc gacggcaatt ggtgatttcg
    38401 gcagtgcggc aggagagctg cccgtgcctg tggagctggc ggaggcctgt gcgcatgccg
    38461 tcatgaagag cgggatcgat cttgccgttt cttactgtat gcaggtggac cacgggttcg
    38521 cccagccgct ggagttcctg ctcggtgggc tggataaggt gccagttctg cctgtgttca
    38581 tcaacggtgt cgccacgccg ctgcccggtt tccagcgtac ccgcatgttg ggtgaagcca
    38641 ttggacgttt caccagcact ctcaataaac gcgtgctgtt cctgggttcc ggtgggcttt
    38701 cccatcagcc gccggtgccc gaactggcga aagccgatgc ccatatgcgc gaccgtctgt
    38761 tggggagcgg gaaagattta cccgccagtg agcgcgaatt gcgtcagcaa cgggtgatta
    38821 gcgccgctga gaagtttgtt gaggatcaga gaacgctgca tccgctcaac ccgatttggg
    38881 ataaccagtt catgactttg ctggagcagg gacgcataca ggaactggat gccgtcagta
    38941 acgaagagct ttccgccatt gccggaaagt cgacacatga aatcaaaacc tgggtcgccg
    39001 cttttgccgc tatttctgcg tttggcaact ggcgtagcga agggcgttat taccgcccaa
    39061 tcccggagtg gattgccgga tttggctcgt taagcgccag aacagagaac tgaatatgca
    39121 ggagaagatg atgagttatc agccacaaac cgaagccgcc accagccgtt ttctgaatgt
    39181 agaagaagcg ggtaaaacgc tgcgcatcca ttttaatgac tgcggacaag gcgacgaaac
    39241 cgttgtcctg ctgcatggtt ccggcccggg tgctactggc tgggcgaact tcagccgcaa
    39301 tatcgatccg ctggtagagg cgggctatcg ggtgatcctg ctggattgtc cgggttgggg
    39361 caagagcgat tcggtcgtta atagtggttc gcgatcggat cttaatgcac gaatcctgaa
    39421 aagcgtggtg gatcaactgg atatcgccaa aatccacctg ctgggcaact cgatgggggg
    39481 ccatagttct gtggcgttca cccttaaatg gccggagcgc gtcggcaaac tggtgctgat
    39541 gggcggcggt acgggcggca tgagtttgtt tacgccgatg ccaaccgaag gtattaagcg
    39601 actgaatcag ctttatcgtc agccgactat cgaaaacctg aagctgatga tggatatctt
    39661 cgtttttgat accagcgatt tgaccgacgc cctgtttgaa gcgcgcctga ataatatgct
    39721 gtcgcgccgc gatcacctgg aaaacttcgt taagagcctg gaagctaatc cgaaacagtt
    39781 cccggatttt ggcccacgtc tggcggaaat caaagcgcaa accctgattg tctgggggcg
    39841 caacgaccgc tttgtgccga tggatgcggg tctgcgtctg ctgtccggca ttgccggttc
    39901 tgaactgcat atcttccgcg actgtggtca ctgggcgcag tgggaacatg ccgacgcttt
    39961 caatcaactg gtgctgaatt tcctcgcacg cccttaagga atggtcatga cgaagcatac
    40021 tcttgagcaa ctggcggcgg atttacgccg cgccgcagag cagggcgaag cgattgcacc
    40081 gctgcgcgat ctgattggta tcgataacgc tgaagcggct tacgccattc agcacataaa
    40141 tgtgcaacat gacgttgcgc aggggcgtcg cgtggtaggg cgtaaagtgg gcctgacaca
    40201 tccgaaagtg caacaacaac tgggcgttga tcaaccggat tttgggacgt tatttgccga
    40261 catgtgttat ggcgataacg aaatcattcc tttttcccgt gttctgcaac cccgcattga
    40321 agcggagatc gcactggtgt tgaaccgcga tttgcccgca accgatatca ccttcgacga
    40381 attgtataac gccattgaat gggtacttcc ggcgctggaa gtggtgggga gccgcattcg
    40441 cgactggtcg attcagtttg tcgataccgt ggcagataac gcctcctgtg gggtgtatgt
    40501 catcggcggt ccggcgcaac gtccggcggg gttagacctg aaaaactgcg ccatgaagat
    40561 gacgcgtaat aacgaagagg tttctagcgg gcgcggcagc gaatgcctgg gacatccgct
    40621 taatgcggcc gtctggctgg cacgcaaaat ggccagtctg ggtgaaccgc tgcgcaccgg
    40681 agatatcatt cttaccgggg cattaggtcc gatggtggcg gtgaatgcgg gcgatcgttt
    40741 tgaagcccat attgaaggca taggttcagt tgctgcgaca ttttcaagcg cagccccaaa
    40801 aggaagtctg tcatgagtaa gcgtaaagtc gccattatcg gttctggcaa cattggtacc
    40861 gatctgatga ttaaaatttt gcgtcacggt cagcatctgg agatggcggt gatggttggc
    40921 attgatcctc agtccgacgg tctggcgcgc gccagacgta tgggcgtcgc caccacccat
    40981 gaaggggtga tcggactgat gaacatgcct gaatttgctg atatcgacat tgtatttgat
    41041 gcgaccagcg ccggtgctca tgtgaaaaac gatgccgctt tacgcgaagc gaaaccggat
    41101 attcgcttaa ttgacctgac gcctgctgcc atcggccctt actgcgtgcc ggtggttaac
    41161 ctcgaggcga acgtcgatca actgaacgtc aacatggtca cctgcggcgg ccaggccacc
    41221 attccaatgg tggcggcagt ttcacgcgtg gcgcgtgttc attacgccga aattatcgct
    41281 tctatcgcca gtaaatctgc cggacctggc acgcgtgcca atatcgatga atttacggaa
    41341 accacttccc gagccattga agtggtgggc ggcgcggcaa aagggaaggc gattattgtg
    41401 cttaacccag cagagccacc gttgatgatg cgtgacacgg tgtatgtatt gagcgacgaa
    41461 gcttcacaag atgatatcga agcctcaatc aatgaaatgg ctgaggcggt gcaggcttac
    41521 gtaccgggtt atcgcctgaa acagcgcgtg cagtttgaag ttatcccgca ggataaaccg
    41581 gtcaatttac cgggcgtggg gcaattctcc ggactgaaaa cagcggtctg gctggaagtc
    41641 gaaggcgcag cgcattatct gcctgcctat gcgggcaacc tcgacattat gacttccagt
    41701 gcgctggcga cagcggaaaa aatggcccag tcactggcgc gcaaggcagg agaagcggca
    41761 tgaacggtaa aaaactttat atctcggacg tcacattgcg tgacggtatg cacgccattc
    41821 gtcatcagta ttcgctggaa aacgttcgcc agattgccaa agcactggac gatgcccgcg
    41881 tggattcgat tgaagtggcc cacggcgacg gtttgcaagg ttccagcttt aactatggtt
    41941 tcggcgcaca tagcgacctt gaatggattg aagcggcggc ggatgtggtg aagcacgcca
    42001 aaatcgcgac gttgttgctg ccaggaatcg gcactattca cgatctgaaa aatgcctggc
    42061 aggctggcgc gcgggtggtt cgtgtggcaa cgcactgtac cgaagctgat gtttccgccc
    42121 agcatattca gtatgcccgc gagctcggaa tggacaccgt tggttttctg atgatgagcc
    42181 atatgaccac gccggagaat ctcgccaagc aggcaaagct gatggaaggc tacggtgcga
    42241 cctgtattta tgtggtggat tctggcggtg cgatgaacat gagcgatatc cgtgaccgtt
    42301 tccgcgccct gaaagcagag ctgaaaccag aaacgcaaac tggcatgcac gctcaccata
    42361 acctgagtct tggcgtggcg aactctatcg cggcggtgga agagggctgc gaccgaatcg
    42421 acgccagcct cgcgggaatg ggcgcgggcg caggtaacgc accgctggaa gtgtttattg
    42481 ccgccgcgga taaactgggc tggcagcatg ggaccgatct ctatgcgtta atggatgccg
    42541 ccgacgacct ggtgcgtccg ttgcaggatc gaccggtacg agtcgatcgc gaaacgctgg
    42601 cgctgggata cgctggtgtt tactcgagct tcctgcgtca ctgtgaaacg gcggcggcgc
    42661 gttatggctt aagtgcggtg gatattctcg ttgagctggg caaacgccgg atggttggcg
    42721 gccaggagga tatgatcgtt gacgtggcgc tggatctgcg caacaacaaa taatgatgac
    42781 tgccgagaac gtgcattttg tatgcccatc ccagcacgac tgccggatgc ggcgtgaacg
    42841 ccttatccgg cctacggatg gcgtgagaat ttgtaggtct gataagacgc gttagcgtcg
    42901 catcaggcat ctgcgcacga ctgccggatg cggcgtgaac gccttatccg gcctacggat
    42961 ggcgcgggaa tttgtaggcc tgataagacg cgttagcgtc gcatcaggca tctgcgcacg
    43021 actgccggat gcggcgtgaa cgccttatcc ggcctacggg tggcgcgaga atttgtaggc
    43081 ctgataagac gcgttagcgt cgcatcaggc atctgcgcac gactgccgga tgcggcgtaa
    43141 acgccttatc cggcctacgg atggcgcggg aatttgtagg cctgataaga cgcgttagcg
    43201 tcgcatcagg catctgcaca cgactgccgg atgcgataaa cgtcttgtcc ggcctacatt
    43261 tcgcccgtag gcagtcatta aatagttctg attacgcggc tggcaatgta tcagtcgcga
    43321 ttcacctgca ctcgcaacga ggttcatctt atgtcgactc gtaccccttc atcatcttca
    43381 tcccgcctga tgctgaccat cgggctttgt tttttggtcg ctctgatgga agggctggat
    43441 cttcaggcgg ctggcattgc ggcgggtggc atcgcccagg ctttcgcact cgataaaatg
    43501 caaatgggct ggatatttag cgccggaata ctcggtttgc tacccggcgc gttggttggc
    43561 ggaatgctgg cggaccgtta tggtcgcaag cgcattttga ttggctcagt tgcgctgttt
    43621 ggtttgttct cactggcaac ggcgattgcc tgggatttcc cctcactggt ctttgcgcgg
    43681 ctgatgaccg gtgtcgggct gggggcggcg ttgccgaatc ttatcgccct gacgtctgaa
    43741 gccgcgggtc cacgttttcg tgggacggca gtgagcctga tgtattgcgg tgttcccatt
    43801 ggcgcggcgc tggcggcgac actgggtttc gcgggggcaa acttagcatg gcaaacggtg
    43861 ttttgggtag gtggtgtggt gccgttgatt ctggtgccgc tattaatgcg ctggctgccg
    43921 gagtcggcgg ttttcgctgg cgaaaaacag tctgcgccac cactgcgtgc cttatttgcg
    43981 ccagaaacgg caaccgcgac gctgctgctg tggttgtgtt atttcttcac tctgctggtg
    44041 gtctacatgt tgatcaactg gctaccgcta cttttggtgg agcaaggatt ccagccatcg
    44101 caggcggcag gggtgatgtt tgccctgcaa atgggggcgg caagcgggac gttaatgttg
    44161 ggcgcattga tggataagct gcgtccagta accatgtcgc tactgattta tagcggcatg
    44221 ttagcttcgc tgctggcgct tggaacggtg tcgtcattta acggtatgtt gctggcggga
    44281 tttgtcgcgg ggttgtttgc gacaggtggg caaagcgttt tgtatgccct ggcaccgttg
    44341 ttttacagtt cgcagatccg cgcaacaggt gtgggaacag ccgtggcggt agggcgtctg
    44401 ggggctatga gcggtccgtt actggccggg aaaatgctgg cattaggcac tggcacggtc
    44461 ggcgtaatgg ccgcttctgc accgggtatt cttgttgctg ggttggcggt gtttattttg
    44521 atgagccgga gatcacgaat acagccgtgc gccgatgcct gacgtgcctt attaggcagg
    44581 ggcgaaaggg acttcacccc aatacaccta cggcgtttac aggtatactc gctaaaaatt
    44641 attcagcggg tttggaaaca aagatggcaa aacttacctt acaagagcag ttgctcaaag
    44701 caggattagt caccagcaaa aaagcggcga aggtggagag aacggcgaaa aaatcgcgcg
    44761 ttcaggcgcg tgaagctcgg gcggcggtag aagaaaataa aaaggcacag cttgagcgtg
    44821 ataaacagct tagcgaacag caaaaacaag cggcgttggc gaaagaatat aaagctcagg
    44881 tgaagcagct tattgaaatg aaccgaatca ccattgccaa tggcgatatt ggttttaact
    44941 tcactgacgg caatctgatt aagaagattt ttgtcgataa gctcacacag gcgcagttga
    45001 ttaatggtcg tctggcgatt gcccgcttgt tggtcgataa caatagcgaa ggtgaatacg
    45061 ccattattcc cgccagcgtt gccgataaaa ttgctcagcg cgatgccagc agtatagtgt
    45121 tgcacagcgc gctcagcgcc gaagagcagg atgaagacga cccgtatgcc gacttcaaag
    45181 tgcctgatga tttgatgtgg taaacataga taagtcgtgc gcagatgcct gatgcgacgc
    45241 tatgcgcgtc ttatcaggcc tacggtttat gggcgaagtg tagaccggat aaggcgttca
    45301 cgccgcatcc ggcagtcgtg cgccatgcct gatgcgacgc tttgcgcgtc ttatcaggcc
    45361 tacggcttac gggcgaagtg taggccggat aaggcgttca cgccgcatcc ggcagtcgtg
    45421 ctattatcaa cgcatattca gtttattggc gtggtaggca atatgctcgc caataaaact
    45481 ggagacaaaa taatagctgt gatcataacc ctcgtgataa cggattaacg tcttgatatt
    45541 catctcctgg cagatctttt caagatttgg agtccgcagc tgttctgcgt aaaaatcatc
    45601 actcaacccc tgatcaacca tgatttccgc aacgcgttga ccttgtgaaa taagactcac
    45661 cgggtcgtaa tccaaccagg catctttatt ttcagcaaga tatgcagcaa aggcttgctg
    45721 tccccacggc acttgcgatg gggagacaat gggcgaaaac gccgagacgc tgacatattc
    45781 atctgggtta cgtaacgcca gcaccagcgc gcccagcccg cccatagaat gaccagagat
    45841 agactttttg gccgttgccg gaaaatgatg catcactaaa tccggcagct cgttgcggat
    45901 atagtcatac attttgtaat gttcattcca cggcgcttgc gtcgcgttca ggtaaaaccc
    45961 ggcaccttgc ccgagatcgt aacggtcagc atctgcgaca tgactgcctc gcggactggt
    46021 gtccggcgca acaacaataa tgttgtgctc agccgcgtaa cgctgcatcc ccgatttagt
    46081 aatgaaattc tgctcgttgc aggtcaggcc tgaaagccag tacagcaccg gcaatttttc
    46141 attcgcggct tttggtggga gatagacgcc gacattcatt tcacatttca gtgattggga
    46201 ataatgccga tacacatttt gccagccgcc aaagctggca tgtttttcaa tgagttccat
    46261 cagtcattat ctcacggtta atcccccgga cggctgccca gggagagtat taagaacccc
    46321 gtctgaagtg gacggggtat acctgcggga aatcagtaac gaattacggt tcgaatggat
    46381 ttgccttcat gcatcaggtc gaaggcgtca ttaatttcat caaggctcat ggtatgcgtg
    46441 acaaacggtt ccagatcgat atcacctttc atcgcatctt caaccatacc cggtaactgg
    46501 gaacgacctt tcacgccgcc aaacgcggaa cctttccata cgcgaccagt gaccaactgg
    46561 aatggacggg tggagatttc ctgaccagaa cctgccaccc cgatgatcac cgactgaccc
    46621 cagccgcggt gtgcactttc cagcgccgca cgcatcacgt tgacgttacc gatgcattca
    46681 aaggtatggt cgatacccca tttgttgata tccagcagga catctttaat cggtttgtcg
    46741 tagtcattcg ggttaatgca gtcggtagca ccgaagcgac gagccagatc gaatttcttc
    46801 gggttggtat cgatagcgat aatccgtccc gctttcgcct gacgcgcgcc ctgaaccact
    46861 gccagaccaa tcgcgccaag accaaacacg gcaacagaat cacctggctg gactttagct
    46921 gtgttgtgca ccgcgccaat accggtggtc acgccacagc ccagcaggca gacgtgttca
    46981 tggtttgctt ctggattaat tttggccaga gacacttccg cgaccacggt gtattcactg
    47041 aatgttgagc atcccatgta gtgataaagc ggctgcccgt tgtaagaaaa acgggtggtg
    47101 ccgtctggca tcaagccttt accctgggtt tcgcgaaccg caacacagag gttagttttg
    47161 ccagaacgac agaactcaca ctcgccgcac tccgcggtgt aaagcgggat cacatggtcg
    47221 ccaggtttga cgctggttac gccttcaccg acttcaacca caacgccggc cccttcgtga
    47281 ccgagaacca ccgggaatac accttccggg tcatccccgg agagggtaaa tgcgtcggta
    47341 tggcaaacgc cggtatgggt gactttaatc agcacttcac cttttttcgg tggtgcaacg
    47401 tcaatttcaa cgatttccag cggtttaccg ggagcaaatg caacggcagc acgtgatttc
    47461 atctctcgct cttcctcaat atggtaatag attcagctat ttaagatagg ctcgaaccag
    47521 ttcaatagtg tcgtcaacgg attggctgac ttcgcggctg tagcagtcat ttcggtcaaa
    47581 cgtttcccgg atatggcttt caagcacttc tgccatcagc ccattagccg cgccccgaac
    47641 ggcagcgatc tgttggagta tggcacggca ttcggcatca ccctccagcg accgttccag
    47701 agcatcaatc tgccctcgaa tacgacgaac tcgagtaagg acctttttct tctcttccgg
    47761 agtactgggc atttcgcacc tcattatctg cacgcaatat actatagggg ggtatgctat
    47821 atgtcaatgc atacccccct atagtatata acactggaga ataaaattta tccggtgaat
    47881 gtggtcggaa aacaaagagg aaaggggggg gctaatcggc agggaaggcc gccccggata
    47941 gcgggcggca gaaggaatca gaatttccag gtcagatggg ctgcaagttg cagaccgtta
    48001 taatcatcgg ttggggtgtc gtaccacact ttacctgccg tcagcccgag attaagttgc
    48061 tcagtcagcg gttgaatacg ttgcagactg acgctcttca tgctgccgta gcgtgtttct
    48121 ggcgtccagt cataggtgta agcgcctgtt ccgcggctta gccatagttg cgtataacca
    48181 gtgccgcgcg ggtcattcag acgcacggaa atcatattgc tataactacc acctgcatcg
    48241 ctggagtcat aatgggtata gcggtagctg gtgatcaccg ggccagtata gagtgatacg
    48301 ccgccttgcc aggcatcgac ttcgacatca tcgtaatatt tagtgtagcg ataaccggtc
    48361 gtgaaaagcg tttttggcaa cagggccagg ttaatatcct gacgaaaatc ctggcgggca
    48421 aagaccggcg tattatccgc aaaggcaata cccgttcggg ttgtcagcca gttattccat
    48481 ttataccaga ccgcaccctg accgcgagtg gcattgaaat gttcagtttc ataatcacga
    48541 cgcccctggg aaagattaaa aagcagcgtt gcgttttcaa ctttcgccac cagttcagca
    48601 tacgctaaat tacggttgcc atgatcgcca gaataatcgg taaaatcgta gcccgcggta
    48661 atggaggtta acccggcata agcgggcaat gcgctaaaaa tggccgccgc taataacgtc
    48721 cgttttatca ttttaatctc ctgtacggat aagttcttgt cggagtgaat aagttccggc
    48781 aggtaaatta cgttctacaa tcacgcgcgg gccaagttgc gtgttcgggg aaataattcg
    48841 cccaggcaaa
//
LOCUS       DAPHKZ010000021        48237 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.021, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000021 DAPHKZ010000000
VERSION     DAPHKZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 48237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48237
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.021"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..550
                     /locus_tag="RH288_001296"
     CDS             <1..550
                     /locus_tag="RH288_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4030369.1"
                     /translation="KTAIAAAMVMGAFTSTATIAAGNNGTARFYGTIEDSVCSIVPDD
                     HKLEVDMGDIGAEKLKNNGTTTPKNFQIRLQDCVFDTQETMTTTFTGTVSSANSGNYY
                     TIFNTDTGAAFNNVSLAIGDSLGTSYKSGMGIDQKIVKDTATNKGKAKQTLNFKAWLV
                     GAADAPDLGNFEANTTFQITYL"
     gene            632..3278
                     /gene="yfcU"
                     /locus_tag="RH288_001297"
                     /pseudo
     CDS             632..3278
                     /gene="yfcU"
                     /locus_tag="RH288_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher protein YfcU"
     gene            3298..4050
                     /locus_tag="RH288_001298"
     CDS             3298..4050
                     /locus_tag="RH288_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV4030370.1"
                     /translation="MSDLLCSAKLGAMTLALLLSATSLSALASVTPDRTRLIFNESDK
                     SISVTLRNNDPKLPYLAQSWIEDEKGNKITSPLTVLPPVQRIDSMMNGQVKVQGMPDI
                     NKLPADRESMFYFNVREIPPKSNKPNTLQIALQTRIKLFWRPKALEKVSMKSPWQHKV
                     TLTRSGQAFTVNNPTPYYVIISNASAQKNGNPAAGFSPLVIEPKTTVPLNVKMDSVPV
                     LTYVNDFGARMPLFFQCNGNSCQVDEEQSRKG"
     gene            4050..4562
                     /locus_tag="RH288_001299"
     CDS             4050..4562
                     /locus_tag="RH288_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4030371.1"
                     /translation="MTGGVMSQKFVVGAGLLVCSVCSLSAMAGSKPVDLILRVLVDAP
                     PPCSIKGSQVEFGNMIADNVDGTNYRQDAKYTLNCTNSLANDLRMQLKGNTSTINGET
                     VLSTNITGLGIRIENSADNSLFAVGENSWTPFNINNQPQLKAVPVKASGAQLAAGEFN
                     ASLTMVVDYQ"
     gene            4559..5047
                     /locus_tag="RH288_001300"
     CDS             4559..5047
                     /locus_tag="RH288_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4030372.1"
                     /translation="MRKTFLTLLCVSSAIAHAADEDITFHGTLLSPPTCSISGGKTIE
                     VEFRDLIIDDINGNYGRKEVPYELTCDSTTRHPDWEMTLTWTGTQTSFNDAAIETDVP
                     GFGIELQHDGQRFKLNTPLAINATDFTQKPKLEAVPVKASDAVLSDTNFSAYATLRVD
                     YQ"
     gene            5044..5583
                     /locus_tag="RH288_001301"
     CDS             5044..5583
                     /locus_tag="RH288_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4030373.1"
                     /translation="MNKSMIQSGGYVLLAGLILAMSSTLFAADNNLHFSGNLLSKSCA
                     LVVDGQYLAEVRFPTVSRQDLNVAGQSARVPVVFKLKDCKGPAGYNVKVTLTGVEDSE
                     QPGFLALDTSSTAQGVGIGMEKTDGMQVAINNTNGATFALTNGNNDINFRAWLQAKSG
                     RDVTIGEFTASLTATFEYI"
     gene            5585..6406
                     /locus_tag="RH288_001302"
     CDS             5585..6406
                     /locus_tag="RH288_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcO family protein"
                     /protein_id="HDV4030374.1"
                     /translation="MKILRWLFALVMLIATTEAMAAGHSVDVYYGYNGDSRNIATFNL
                     KIMMPSAVYVGEYKSSQWLMTGEILQNVSWSGPPPAPSVKLIGYHQNINKASCPGLPS
                     GWNCGYYTFEVIVSAEIESYFSCPWLVIMNDSEASPGGVTYQGPDSHDTICPSVSVQP
                     YDVSWNENYVSKSKLLTLQSTGGVVEKTLSTYLMKDGKLCDSTQMNETGGYCRWVAQM
                     ITFTASGCDKAEVSVTPNRHPITDKQLHDMVVRVDTSSMQPIDSTCRFQYILNEL"
     gene            complement(6477..7028)
                     /gene="smrB"
                     /locus_tag="RH288_001303"
     CDS             complement(6477..7028)
                     /gene="smrB"
                     /locus_tag="RH288_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HDV4030375.1"
                     /translation="MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPV
                     KRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVEEWLPPELP"
     gene            7194..8126
                     /gene="prmB"
                     /locus_tag="RH288_001304"
     CDS             7194..8126
                     /gene="prmB"
                     /locus_tag="RH288_001304"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDV4030376.1"
                     /translation="MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGH
                     EFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPDAEVD
                     AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKEQLIAAREHFAIYKD"
     gene            8161..9246
                     /gene="aroC"
                     /locus_tag="RH288_001305"
     CDS             8161..9246
                     /gene="aroC"
                     /locus_tag="RH288_001305"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDV4030377.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLDIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGI
                     LGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRQRAQNADVKTDIPRW"
     gene            9250..10074
                     /gene="mepA"
                     /locus_tag="RH288_001306"
     CDS             9250..10074
                     /gene="mepA"
                     /locus_tag="RH288_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HDV4030378.1"
                     /translation="MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGC
                     IVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVSTLWKPEI
                     FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPSGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI"
     gene            10074..10883
                     /locus_tag="RH288_001307"
     CDS             10074..10883
                     /locus_tag="RH288_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDV4030379.1"
                     /translation="METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQ
                     YVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGMN"
     gene            10883..11431
                     /gene="epmC"
                     /locus_tag="RH288_001308"
     CDS             10883..11431
                     /gene="epmC"
                     /locus_tag="RH288_001308"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
                     /protein_id="HDV4030380.1"
                     /translation="MNSTHHYEQLIEIFNSCFADDFNTRLIKGDDEPIYLPADAEVPY
                     NRIVFAHGFYASAIHEISHWCIAGKARRELVDFGYWYCPDGRDAQTQSQFEDVEVKPQ
                     ALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLTNGIPERPARFIKA
                     LQNYYHTPELTAEQFPWPEALN"
     gene            11465..11743
                     /locus_tag="RH288_001309"
     CDS             11465..11743
                     /locus_tag="RH288_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HDV4030381.1"
                     /translation="MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELES
                     GDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWENLFQQASQQ"
     gene            complement(11864..13870)
                     /gene="mnmC"
                     /locus_tag="RH288_001310"
     CDS             complement(11864..13870)
                     /gene="mnmC"
                     /locus_tag="RH288_001310"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HDV4030382.1"
                     /translation="MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNQLEVRFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEK
                     FPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDAGRVTLDLWFGDINEL
                     TSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRR
                     GLQDAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFAR
                     RFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVA
                     TNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNLSRKDDCWLLNFAGDQ
                     QATHSVVVLANGHQISRFSQTSTLPVYSVAGQVSHIPTTPELAELKQVLCYDGYLTPQ
                     NPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKEARCGV
                     RCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRGLCSAP
                     LCAEILAAQMSDEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG"
     gene            14029..15249
                     /gene="fabB"
                     /locus_tag="RH288_001311"
     CDS             14029..15249
                     /gene="fabB"
                     /locus_tag="RH288_001311"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HDV4030383.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGM
                     RSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLI
                     AGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGF
                     GGTNATLVMRKLKD"
     gene            15514..16692
                     /locus_tag="RH288_001312"
     CDS             15514..16692
                     /locus_tag="RH288_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose transporter"
                     /protein_id="HDV4030384.1"
                     /translation="MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     DLGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAA
                     ILPVSAPFKFALLVIGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
                     LAVGAPLGLLIHSHYGFAALAITTMVLPLLAWACNGTVRKVPALAGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRF
                     GGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQ
                     VRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
                     "
     gene            complement(16689..17684)
                     /gene="flk"
                     /locus_tag="RH288_001313"
     CDS             complement(16689..17684)
                     /gene="flk"
                     /locus_tag="RH288_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HDV4030385.1"
                     /translation="MIQPISGPPPGQPPGQGDNLPSGTGNQPLSSQQRTSLESLMTKV
                     TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQ
                     LGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
                     DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWL
                     QARQTLSQQNTPTLESLQMTLKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDIL
                     NQLYQRRVKGIDPRVMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR"
     gene            17783..18919
                     /gene="pdxB"
                     /locus_tag="RH288_001314"
     CDS             17783..18919
                     /gene="pdxB"
                     /locus_tag="RH288_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HDV4030386.1"
                     /translation="MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVR
                     SVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSS
                     LLMLAERDGFSLYDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRS
                     LDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALL
                     TCLNEGQKLSVVLDVWEGEPELNVELLKKVDIGTPHIAGYTLEGKARGTTQVFEAYSK
                     FIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR"
     gene            18985..19998
                     /locus_tag="RH288_001315"
     CDS             18985..19998
                     /locus_tag="RH288_001315"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDV4030387.1"
                     /translation="MSEGWNIAVLGATGAVGEALLETLAERQFPVGEIYALARNESAG
                     EQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATAAWVEEATNSGCLVIDSSGLFAL
                     EPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVD
                     EVRKILQDEGLMISASVVQAPVFYGHAQMVNFEALRPLAAEEARDAFVQGEDIVLSEE
                     NEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            19998..20810
                     /gene="truA"
                     /locus_tag="RH288_001316"
     CDS             19998..20810
                     /gene="truA"
                     /locus_tag="RH288_001316"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDV4030388.1"
                     /translation="MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALS
                     QVANEPITVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKA
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHN
                     QPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD"
     gene            20893..21552
                     /locus_tag="RH288_001317"
     CDS             20893..21552
                     /locus_tag="RH288_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV4030389.1"
                     /translation="MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFS
                     NPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAA
                     K"
     gene            21708..22622
                     /gene="accD"
                     /locus_tag="RH288_001318"
     CDS             21708..22622
                     /gene="accD"
                     /locus_tag="RH288_001318"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HDV4030390.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPEAPREGVVVPPVPDQEPEA"
     gene            22692..23960
                     /gene="folC"
                     /locus_tag="RH288_001319"
     CDS             22692..23960
                     /gene="folC"
                     /locus_tag="RH288_001319"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDV4030391.1"
                     /translation="MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSLVAARLGV
                     LKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPE
                     SAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
                     ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGA
                     LLQRRGVEWNYSVTDHDWAFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENA
                     IRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADA
                     KAEDTVLVCGSFHTVAHVMEVIDARRSGGK"
     gene            23950..24612
                     /gene="dedD"
                     /locus_tag="RH288_001320"
     CDS             23950..24612
                     /gene="dedD"
                     /locus_tag="RH288_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416817.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HDV4030392.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPATIAANNTEFEPEPA
                     PVAPPKPKPVEPPKPKVEAPPAPKPEPKPVVEEKAAPTGKAYVVQLGALKNADKVNEI
                     VGKLRGAGYRVYTSPSTPVQGKITRILVGPDASKDKLKGSLGELKQLSGLSGVVMGYT
                     PN"
     gene            24871..25359
                     /gene="cvpA"
                     /locus_tag="RH288_001321"
     CDS             24871..25359
                     /gene="cvpA"
                     /locus_tag="RH288_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HDV4030393.1"
                     /translation="MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGV
                     CFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RA"
     gene            25396..26913
                     /gene="purF"
                     /locus_tag="RH288_001322"
     CDS             25396..26913
                     /gene="purF"
                     /locus_tag="RH288_001322"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDV4030394.1"
                     /translation="MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
                     NRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLG
                     FDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIDAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG"
     gene            27008..27577
                     /gene="ubiX"
                     /locus_tag="RH288_001323"
     CDS             27008..27577
                     /gene="ubiX"
                     /locus_tag="RH288_001323"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin prenyltransferase UbiX"
                     /protein_id="HDV4030395.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTL
                     SLETDFSLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
                     DVINQTVNRVLDQFAITLPEDLFARWQGA"
     gene            27843..28625
                     /gene="argT"
                     /locus_tag="RH288_001324"
     CDS             27843..28625
                     /gene="argT"
                     /locus_tag="RH288_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HDV4030396.1"
                     /translation="MKKSILALSLLVGLSTAASSYAALPETVRIGTDTTYAPFSSKDA
                     KGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVV
                     AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGSSVKDKKYFGDGTG
                     VGLRKDDAELTAAFNKALGELRQDGTYDKMAKKYFDFNVYGD"
     gene            28846..29628
                     /gene="hisJ"
                     /locus_tag="RH288_001325"
     CDS             28846..29628
                     /gene="hisJ"
                     /locus_tag="RH288_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HDV4030397.1"
                     /translation="MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNS
                     QGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            29718..30404
                     /gene="hisQ"
                     /locus_tag="RH288_001326"
     CDS             29718..30404
                     /gene="hisQ"
                     /locus_tag="RH288_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HDV4030398.1"
                     /translation="MLYGFSGVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRL
                     SGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPSMMRYALPGIGNNWQV
                     ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERR
                     YSVGVKRADL"
     gene            30401..31117
                     /locus_tag="RH288_001327"
     CDS             30401..31117
                     /locus_tag="RH288_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4030399.1"
                     /translation="MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFL
                     AIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLI
                     SLFRRAEKRWLQHVKPSSTH"
     gene            31125..31898
                     /gene="hisP"
                     /locus_tag="RH288_001328"
     CDS             31125..31898
                     /gene="hisP"
                     /locus_tag="RH288_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HDV4030400.1"
                     /translation="MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGK
                     STFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     STHVIFLHQGKIEEEGAPEQLFGNPQSPRLQRFLKGSLK"
     gene            32095..32985
                     /gene="rpnB"
                     /locus_tag="RH288_001329"
     CDS             32095..32985
                     /gene="rpnB"
                     /locus_tag="RH288_001329"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnB"
                     /protein_id="HDV4030401.1"
                     /translation="MTISTTSTPHDAVFKSFLRHPDTARDFIDIHLPAPLRKLCDLTT
                     LKLEPNSFIDEDLRQYYSDLLWSVKTQEGVGYIYVVIEHQSKPEELMAFRMMRYSIAA
                     MQNHLDAGYKELPLVLPMLFYHGCRSPYPYSLCWLDEFAEPAIARKIYSSAFPLVDIT
                     VVPDDEIMQHRKMALLELIQKHIRQRDLLGLVDQIVSLLVTGNTNDRQLKALFNYVLQ
                     TGDAQRFRAFIGEIAERAPQEKEKLMTIADRLREEGAMQGKHEEALRIAQEMLDRGLD
                     RELVMMVTRLSPDDLIAQSH"
     gene            complement(33033..33926)
                     /locus_tag="RH288_001330"
     CDS             complement(33033..33926)
                     /locus_tag="RH288_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HDV4030402.1"
                     /translation="MNIVITGGTGLIGRHLIPRLLELGHQITVVTRNPQKASSVLGPR
                     VTLWQGLADQSNLNGVDAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINAS
                     DTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
                     LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRG
                     PFNMVSPYPVRNEQFAHALGHALHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRL
                     EEAGFAFRWYDLEEALADVVR"
     gene            complement(33947..34309)
                     /gene="folX"
                     /locus_tag="RH288_001331"
     CDS             complement(33947..34309)
                     /gene="folX"
                     /locus_tag="RH288_001331"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="HDV4030403.1"
                     /translation="MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADK
                     ARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDK
                     LHALRYADSVSMTLSWQR"
     gene            complement(34366..35013)
                     /gene="yfcG"
                     /locus_tag="RH288_001332"
     CDS             complement(34366..35013)
                     /gene="yfcG"
                     /locus_tag="RH288_001332"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HDV4030404.1"
                     /translation="MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFL
                     RISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLF
                     WQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
                     IADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS"
     gene            35149..35793
                     /gene="yfcF"
                     /locus_tag="RH288_001333"
     CDS             35149..35793
                     /gene="yfcF"
                     /locus_tag="RH288_001333"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HDV4030405.1"
                     /translation="MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGE
                     HLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARA
                     RQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLVLGQPNL
                     FGEWCIADTDLALMINRLVLHGDEVPERLVDYATFQWQRASVQRFIALSAKQSG"
     gene            35849..36400
                     /gene="yfcE"
                     /locus_tag="RH288_001334"
     CDS             35849..36400
                     /gene="yfcE"
                     /locus_tag="RH288_001334"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311211.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDV4030406.1"
                     /translation="MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRN
                     ALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRLFL
                     THGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
                     DNDVLSVIALNDQSIIAQVAINP"
     gene            36458..37000
                     /gene="yfcD"
                     /locus_tag="RH288_001335"
     CDS             36458..37000
                     /gene="yfcD"
                     /locus_tag="RH288_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HDV4030407.1"
                     /translation="MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAE
                     HGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
                     LALWMKRNAKNEAVETETAE"
     gene            complement(37033..38553)
                     /gene="yfcC"
                     /locus_tag="RH288_001336"
     CDS             complement(37033..38553)
                     /gene="yfcC"
                     /locus_tag="RH288_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDV4030408.1"
                     /translation="MSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTS
                     GSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSL
                     GGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQAD
                     VEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRL
                     NGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAI
                     SGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH"
     gene            complement(38743..40887)
                     /gene="pta"
                     /locus_tag="RH288_001337"
     CDS             complement(38743..40887)
                     /gene="pta"
                     /locus_tag="RH288_001337"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDV4030409.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     TGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIVANYHANTKDA
                     EVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
                     GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVNNVDPAKLQESSPLPVL
                     GAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSL
                     LVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNT
                     NTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAF
                     RYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGV
                     ELGAGIEIVDPEVVRESYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDG
                     LVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQL
                     AEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGP
                     LQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG
                     MRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ"
     gene            complement(40962..42164)
                     /gene="ackA"
                     /locus_tag="RH288_001338"
     CDS             complement(40962..42164)
                     /gene="ackA"
                     /locus_tag="RH288_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDV4030410.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARI
                     KWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            42502..42957
                     /locus_tag="RH288_001339"
     CDS             42502..42957
                     /locus_tag="RH288_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HDV4030411.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMT
                     RYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAI
                     LNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            43040..43534
                     /locus_tag="RH288_001340"
     CDS             43040..43534
                     /locus_tag="RH288_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HDV4030412.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQM
                     RELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEAR
                     YLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            43545..44195
                     /gene="hxpA"
                     /locus_tag="RH288_001341"
     CDS             43545..44195
                     /gene="hxpA"
                     /locus_tag="RH288_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416796.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpA"
                     /protein_id="HDV4030413.1"
                     /translation="MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLAPEEVLAFIH
                     GKQAITSLRHFMAGKSEADIAAEFTRLEHIEATETEGITALPGAIALLSHLNKAGIPW
                     AIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
                     VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ"
     gene            44282..46114
                     /locus_tag="RH288_001342"
     CDS             44282..46114
                     /locus_tag="RH288_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDV4030414.1"
                     /translation="MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLT
                     VPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTV
                     AGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFR
                     DLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVN
                     GVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPE
                     SELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGML
                     AKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLM
                     GKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMM
                     LGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPV
                     SSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF"
     gene            complement(46173..46772)
                     /gene="yfbR"
                     /locus_tag="RH288_001343"
     CDS             complement(46173..46772)
                     /gene="yfbR"
                     /locus_tag="RH288_001343"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HDV4030415.1"
                     /translation="MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
                     TRLEATLEARRSQEMDYFMEIFVPSFHLSLDEISQDSPL"
     gene            complement(46856..48073)
                     /gene="alaA"
                     /locus_tag="RH288_001344"
     CDS             complement(46856..48073)
                     /gene="alaA"
                     /locus_tag="RH288_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HDV4030416.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDA
                     EHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSL
                     SKFARFLSGYHQL"
BASE COUNT        11363 a        12024 c        13018 g        11832 t
ORIGIN      
        1 taaaacagct attgctgcgg caatggtgat gggcgcgttc acctctacgg caacaatcgc
       61 tgcgggtaac aacggtactg cacgttttta cggcaccatt gaagactcag tgtgttctat
      121 cgttccggac gatcacaaac tggaagttga tatgggtgat atcggtgccg aaaaactgaa
      181 aaataacggc accaccacgc cgaaaaattt ccagattcgc ctgcaagatt gcgtatttga
      241 tactcaggaa acaatgacca ctacctttac tggtaccgtt tcttctgcaa atagcggcaa
      301 ttattacacc attttcaata ccgataccgg tgcggcattt aacaatgtta gcctggcgat
      361 cggtgactct ctgggtacct cttacaaaag cggcatgggt attgaccaga aaatcgtgaa
      421 agatactgcc actaataaag gcaaagcgaa gcagactctg aactttaaag cctggctggt
      481 cggcgcagct gatgcgccag atctgggtaa tttcgaagca aataccacct tccagattac
      541 ttacctgtaa ggcatacccc catagcgaca ctgctatggg gtatttaaat ggattttgac
      601 cgaacaagaa taaaaacgga taaaaacgtg tatgcctgac cattctcttt ttcgattacg
      661 gattcttccg tggtgcattg cgctggcaat gtcagggagt tatagcagtg tctgggctga
      721 agacgacatt cagtttgatt cccgttttct ggaattaaaa ggcgacacaa aaattgatct
      781 gaagcgtttt tccagccagg ggtatgttga gcccggaaaa tacaatttac aggttcaact
      841 aaataaacag ccattggcgg aagagtacga tatttactgg tatgctggtg aagatgacgt
      901 tagcaaaagc tatgcttgtc tgacaccgga actggtggcg cagtttggtt taaaagaaga
      961 cgtggcgaaa aatctgcaat ggagccacga tggtaaatgc ctgaagcccg gtcaactgga
     1021 aggcatggaa attaaggctg atttaagcca gtccgcatta gtcatttcac taccgcaggc
     1081 ttacctcgaa tatacctggc ccgactggga tccaccttct cgttgggatg atggcatctc
     1141 cgggatcatt gcggactaca gcatcactgc gcaaacacga cacgaagaaa atggcggcga
     1201 tgacagtaac gagatcagcg gcaacgggac ggtcggggtt aacctggggc catggcgtat
     1261 gcgcgctgac tggcagacca actatcaaca tacgcgcagt aatgatgatg acgatgaatt
     1321 tggcggcgat gacacacaaa aaaaaatggg agtggagtcg ctattatgcc tggcgggcgt
     1381 taccgtcatt aaaagccaaa ctggcgctgg gcgaagatta cctcaattcc gatattttcg
     1441 acggttttaa ttatgttggt ggcagtgtca gcactgacga tcaaatgttg cctcccaacc
     1501 tgcgcggcta cgcgccagac atttccggcg tggcacacac cacagcaaaa gtgaccgtca
     1561 gccagatggg gcgtgtgatt tacgaaacgc aggttccggc tggaccgttt cgtattcagg
     1621 atcttggtga ttccgtctcc ggtacgttgc atattcgcat tgaagaacag aacggccagg
     1681 tgcaggaata tgacatcagc accgcctcga tgccatacct cactcgccca ggccaggttc
     1741 gctataagat catgatggga cgtccgcaag agtggggcca ccatgtcgag gggggatttt
     1801 tctctggtgc tgaagcctcc tggggcatcg ctaacggctg gtcgttatat ggcggtgcgc
     1861 tgggtgatga aaactatcag tctgcggcgc tgggcgtcgg tcgcgatttg tctaccttcg
     1921 gcgcggtcgc gtttgatgtt actcattcgc ataccaaact ggataaagac accgcttatg
     1981 gcaaaggttc gctggacggt aactccttcc gtgtgagtta ttccaaagac tttgaccagc
     2041 tcaacagccg cgtcactttc gctggatatc gcttctcgga agagaacttt atgaccatga
     2101 gcgagtatct ggatgccagt gacagcgaaa tggtccgtac gggcaacgac aaagagatgt
     2161 acaccgccac ttataaccag aacttccgcg atgcgggtgt ttcggtttat ctcaactata
     2221 cccgccatac ctactgggat cgtgaggagc agacaaacta caacatcatg ctctcccact
     2281 atttcaatat gggcagcatt cgtaatatga gcgtttccct gactggctac cgctacgagt
     2341 atgacaaccg ggcggataag ggcatgtaca tttcgctcag tatgccgtgg ggcgacaaca
     2401 gtaccgttag ctataacggc aactatggca gtgggacgga cagcagccag gtcggttatt
     2461 ttagccgtgt cgatgacgcg actcactatc agttgaacat cggcaccagt gacaaacaca
     2521 ccagcgttga tggctactac agccatgatg gttcgctggc gcaggttgac ctcagtgcga
     2581 actaccatga agggcaatac acctctgcgg gcttgtcgtt acagggcggc gcaacgctta
     2641 ctacccacgg cggcgcactt caccgtaccc agaatatggg cgggacacgc ctgctgattg
     2701 atgccgatgg cgttgccgat gttccggtgg aaggtaacgg ggctgctgtt tataccaata
     2761 tgtttggtaa agccgtcgtt tctgacgtta acaattatta tcgcaatcag gcgtatatcg
     2821 acctcaacaa attgccggaa aacgccgaag caacccagtc ggtggtgcaa gccacgctaa
     2881 ctgaaggagc cattggctac cgcaaatttg ccgtcatcag tggtcaaaaa gcgatggcgg
     2941 tgctgcgttt acaagatggc agccatccac cgtttggcgc agaagtaaaa aatgataacg
     3001 agcagacagt gggccttgtc gatgatgacg gtagtgtcta tctggctggg gtgaaacctg
     3061 gcgaacatat gagtgtgttc tggagtggtg ttgcgcattg cgatatcaac ctgccggacc
     3121 cgctgcctgc cgatctgttt aacggcttgt tactgccatg ccagcataaa ggcaacgtcg
     3181 cgccggttgt tcctgatgac ataaagcctg tcattcagga gcagacgcaa caggtgacac
     3241 ccaccgatcc ccctgtttct gtttcagcta accaataacg tgattaagga atgatccatg
     3301 tctgatttac tttgctctgc caaattgggt gctatgacgc tggcgttact gcttagcgct
     3361 accagtttgt ctgccctggc gtctgtaacg ccagatcgta cccgtttgat atttaatgaa
     3421 agcgacaaat caatcagcgt gacgctgcgt aataacgatc cgaaactccc ttatctggct
     3481 caaagctgga ttgaagatga aaagggtaac aagatcacct cgccgttaac tgtgctgccg
     3541 ccagtgcaac gcatcgattc aatgatgaac gggcaggtaa aagtgcaggg aatgccggat
     3601 atcaacaaat tgccagccga tcgtgaaagc atgttctact ttaacgtgcg cgagatcccg
     3661 ccaaaatcaa acaaacccaa taccctgcaa atcgcgctgc aaacgcgtat caagttgttc
     3721 tggcgaccaa aggcgctgga aaaggtcagt atgaaaagtc cgtggcagca caaggtgacg
     3781 ctcacccgca gcggtcaggc atttaccgtc aataacccaa cgccgtacta cgtgattatc
     3841 agcaacgcca gtgcgcagaa aaacggtaat ccagctgcag ggttctcgcc tctggtcatt
     3901 gagccgaaaa ccacggtacc gctgaatgtg aaaatggata gcgtaccggt gctgacttac
     3961 gtcaacgact ttggcgcacg gatgccgctg ttcttccagt gcaatggcaa cagctgccag
     4021 gtggatgaag agcagagccg caaaggctga tgacgggggg agttatgagt caaaagtttg
     4081 tagtgggcgc agggctgctg gtatgcagtg tctgtagttt atctgctatg gctggtagta
     4141 aacccgtgga tttaattctg cgcgtgttgg tcgatgctcc gccaccctgt tcaatcaagg
     4201 gcagccaggt agagttcggc aatatgattg ctgataacgt tgatggcacc aattatcggc
     4261 aagatgcgaa atacacgttg aactgcacaa acagtcttgc taacgacttg cggatgcaac
     4321 ttaagggcaa tacctcaacg attaacggcg aaacggtact cagtaccaat atcaccgggc
     4381 tgggcattcg gatagaaaat agcgccgata actcattgtt tgccgtcggt gaaaatagct
     4441 ggacgccatt taatatcaat aaccagccac agttgaaggc tgtacctgtg aaggcaagcg
     4501 gggcgcaact tgctgcgggc gagtttaacg ccagtttgac catggtggtg gactatcaat
     4561 gagaaagact ttcttaaccc tgctttgtgt cagtagcgcc atagctcatg ctgctgatga
     4621 agacatcacc tttcacggga cattattgtc accgccaacc tgtagcatca gcggtggtaa
     4681 aaccattgaa gtcgaatttc gcgatctcat tatcgacgac atcaacggca actatggtcg
     4741 taaagaggtg ccatatgaac tcacttgtga ctcgacgacc cgtcatccag attgggagat
     4801 gaccctcacc tggactggta cacaaaccag ttttaatgat gcagcaattg aaactgatgt
     4861 acccggtttt ggtatcgagc ttcagcacga tggtcagcgt tttaaactca atactccgct
     4921 tgctatcaac gccactgatt ttacgcaaaa gccgaagctg gaggccgtac cggtaaaagc
     4981 gagtgatgct gtgttaagcg atacgaattt ttcggcttac gcaacattac gggtggatta
     5041 tcaatgaata aatcaatgat tcagtccggt ggttacgtcc tgttagcggg gctgatattg
     5101 gcaatgagta gcacgttatt cgcggcagat aataatctgc atttctccgg taatttatta
     5161 agtaaatcct gtgcgctggt ggtggatggc caatatctgg cagaggtgcg ctttcccacg
     5221 gtcagtcgtc aggatttgaa cgttgcaggc cagtccgctc gtgtacccgt agtctttaag
     5281 ctgaaagatt gcaaagggcc ggcgggatac aacgtaaaag tcacgctcac gggggtagaa
     5341 gacagcgaac aacccggttt tctggcactg gatacgtcat caaccgctca gggagtggga
     5401 attggcatgg aaaaaaccga cggaatgcag gttgccatca acaatacaaa tggggcgacc
     5461 tttgcgctaa ccaatggcaa taacgatatc aatttcagag cctggctaca ggcgaaaagc
     5521 ggccgtgatg tgacgatcgg tgaatttacc gcctctttaa ctgcgacatt tgagtatatt
     5581 taaaatgaaa atactacgat ggttgttcgc tctggtcatg cttattgcta ctacagaagc
     5641 tatggctgcc gggcatagcg ttgacgttta ctacggttac aacggtgatt cgcgtaatat
     5701 tgcgactttt aatttaaaaa taatgatgcc atccgcagtg tacgttggtg aatataaaag
     5761 tagtcaatgg ctcatgactg gggaaatatt gcaaaatgtg agctggagtg gtcctcctcc
     5821 tgccccttcg gttaagctga ttggctacca tcaaaatatc aacaaagcaa gttgtcctgg
     5881 attaccgtct gggtggaact gcgggtatta tacatttgag gttattgtct ctgcagagat
     5941 tgaatcttac ttttcttgtc catggttggt tattatgaat gactctgaag cctctccagg
     6001 gggcgtgacg tatcaggggc ctgatagtca cgacacgatt tgtccatccg tttctgttca
     6061 accttatgac gtttcatgga atgagaatta tgtcagtaag tcaaaactgc tcaccctgca
     6121 gtcgacgggc ggtgtggttg agaaaacgct ttcaacgtat ttgatgaaag atgggaagtt
     6181 gtgcgacagt acgcagatga atgaaacagg tggttactgc cgctgggttg cacagatgat
     6241 aacttttacc gcgtcgggat gtgacaaggc ggaagtctcg gtcacgccaa atcgacaccc
     6301 tataacggac aaacagttac acgatatggt cgtgcgtgtt gataccagca gtatgcagcc
     6361 aatcgattct acttgccggt tccagtacat actgaatgag ttgtagccct tagatacacc
     6421 aggcaggggc attcgcccct gccattaccc gtacctggcg caacgcgctc aactcctcag
     6481 ggcaactccg gcggcagcca ctcttcgact tcaatcaaca ccaacaacgc cgcatcaccg
     6541 ccatactctt ttggtgcctg atgaaaggcc atcacatgcg gatgttgtgc cagccacagc
     6601 ggtgtttgtt gcttcaaaat atgcttcccg tgcccatgca tcacgcaggc gcaaaacaca
     6661 tgttcacggc ggcaggcggc aatcaacgcc cccagttcct gcttggcctg cagctgcgtc
     6721 agaccgtgta aatccaaaaa caactccggc gaataatcgc cacggcgcag tttcttcgcc
     6781 tcaaaatggc tgacatccgg gcgaacatat ttcaccggac cttcggtatt taataacggc
     6841 tgaaactcat cggagaaata atggctggca tcagcctgct cctggatcaa gcgtttcacc
     6901 ggcacttcgc tgattttttt acgctgcggt cggtggacaa tcgtgtcctg cttaatcttg
     6961 cgagtccccg ccatcaactg gcgaaacaga gcctggtcct cctcgctaag tgttgttttc
     7021 tttttcattt atctgtctct atttctaatt ttcctacagt ttacccgact cgtagcgcaa
     7081 tcgatcgttt taaacgtatt tttcctcact caccgcgcgt gaatgctgat ttatcgtcat
     7141 cttcatggca aactagccgc cgaaattatt gcgatcatgc cctggaggaa tacgtggata
     7201 aaattttcgt tgatgaagca gtaaatgagc tgcaaaccat tcaggacatg ttgcgctggt
     7261 cggtgagccg cttcagcgcg gcaaatatct ggtacggtca cggtaccgat aacccgtggg
     7321 atgaagccgt acagctggtg ttgccttcgc tctacctgcc gctggatatt ccggaagata
     7381 tgcgcaccgc gcgtctgacc tccagcgaaa aacaccgtat tgttgaacgc gtgatccgcc
     7441 gcgtcaatga acgcattccg gtggcttacc tgaccaacaa agcgtggttc tgcggccatg
     7501 aattttacgt cgatgaacgc gtgctggtgc cgcgctcgcc gattggtgaa ctgatcaaca
     7561 ataaatttgc cggacttatc agcaagcaac cgcagcatat tttagatatg tgtactggta
     7621 gcggctgcat cgccattgcc tgtgcttatg ccttcccgga tgcagaagtc gacgcggtgg
     7681 atatctctcc agacgcgctg gcggttgctg aacagaacat cgaagaacac ggtctgatcc
     7741 acaacgtcat tccgattcgt tccgatctgt tccgcgactt gccgaaagtg cagtacgacc
     7801 tgattgtcac taacccgccg tatgtcgatg cggaagatat gtccgacctg ccaaacgaat
     7861 accgccacga gccggaactg ggcctggcat ctggcactga cggcctgaaa ctgacgcgtc
     7921 gcattctcgg taacgcggca gattaccttg ctgatgatgg cgtgttgatt tgtgaagtcg
     7981 gcaacagcat ggtacatctt atggaacaat atccggatgt tccgttcacc tggctggagt
     8041 ttgataacgg cggcgatggt gtgtttatgc tcaccaaaga gcagcttatt gccgcacgag
     8101 aacatttcgc gatttataaa gattaagtaa acacgcaaac acaacaataa cggagccgtg
     8161 atggctggaa acacaattgg acaactcttt cgcgtaacca ccttcggcga atcgcacggg
     8221 ctggcgctcg gctgcatcgt cgatggtgtt ccgccaggca ttccgctgac ggaagcggac
     8281 ctgcaacatg acctcgaccg tcgtcgccct gggacatcgc gctataccac ccagcgccgc
     8341 gagccggatc aggtcaaaat tctctccggt gtttttgaag gcgttactac cggcaccagc
     8401 attggcttgt tgatcgaaaa cactgaccag cgctctcagg attacagtgc gattaaggac
     8461 gttttccgtc caggccatgc cgattacacc tacgaacaaa aatacggtct gcgcgattat
     8521 cgcggcggtg gacgttcttc cgcccgcgaa accgccatgc gcgtggcggc aggagctatt
     8581 gccaaaaaat atctcgccga gaaatttggt attgaaatcc gtggctgcct gacccagatg
     8641 ggcgacattc cgctggatat caaagactgg tcgcaggtcg agcaaaatcc gtttttttgc
     8701 ccggaccccg acaaaatcga cgcgttagac gagttgatgc gtgcgctgaa aaaagagggc
     8761 gactccatcg gcgctaaagt caccgttgtt gccagtggcg ttcctgccgg acttggcgag
     8821 ccggtctttg accgcctgga tgctgacatc gcccatgcgc tgatgagcat caacgcggtg
     8881 aaaggcgtgg aaattggcga cggctttgac gtggtggcgc tgcgcggcag ccagaaccgc
     8941 gatgaaatca ccaaagacgg tttccagagc aaccatgcgg gcggcattct cggcggtatc
     9001 agcagcgggc agcaaatcat tgcccatatg gcgctgaaac cgacctccag cattaccgtg
     9061 ccgggtcgta ccattaaccg ctttggcgaa gaagttgaga tgatcaccaa aggccgtcac
     9121 gatccctgtg tcgggatccg cgcagtgccg atcgcagaag cgatgctggc gatcgtttta
     9181 atggatcacc tgttacggca acgggcgcaa aatgccgatg tgaagactga tattccacgc
     9241 tggtaaaaaa tgaataaaac cgcgattgcg ctgctggctc tgcttgccag tagcgccagc
     9301 ctggcagcga cgccgtggca aaaaataacc caacctgtgc cgggtagcgc acaatcgata
     9361 ggcagttttt ctaatggctg tattgtcggc gctgacacgc tgccgataca gtccgaacat
     9421 tatcaggtca tgcgtaccga tcagcgtcgc tatttcggtc acccggatct ggtgatgttt
     9481 atccagcgtc tgagtagcca ggtgagcaat ctgggcatgg gtacggtgct gattggcgat
     9541 atggggatgc ccgctggtgg gcgtttcaac ggcggtcatg ccagccacca gaccggactg
     9601 gatgtcgata tctttctgca actgccgaaa actcgctgga cctccgcgca gctcttgcgc
     9661 ccgcaagcac tggacttagt ttcccgcgac ggtaaacacg ttgtctccac gctgtggaag
     9721 ccagaaattt tcagcttgat caaactcgcc gcccaggaca aagacgtcac gcgcattttt
     9781 gttaatccgg cgattaaaca acaactttgc cttgatgcgg gcaccgatcg cgactggttg
     9841 cgcaaagtgc gaccctggtt ccagcatcgc gcgcatatgc atgtacgatt acgttgccct
     9901 gccgatagtc tggagtgtga agatcaacct ttaccgccat caggcgatgg ttgcggggca
     9961 gaactgcaaa gctggtttga acctccaaaa ccgggaacaa caaagcctga gaagaagaca
    10021 ccgcctccgt tgccgccttc ctgccaggcg ctactggatg agcacgtgat ctaatggaaa
    10081 cgtttaatag cctgtttatg gtttccccgc tgttgctggg agttctcttt tttgtcgcca
    10141 tgctggcggg atttatcgac tcgattgccg gtggcggtgg gttactcacc attccggcat
    10201 tgatggcagc ggggatgtct cccgctaatg cgctggcaac caataaactg caagcctgcg
    10261 gcggctctat ttccgctact atctacttta ttcgccgcaa agtggttagt ttaagcgatc
    10321 agaaactcaa tatcgccatg acctttgtcg gctcaatgag cggcgcactg ctggtgcaat
    10381 acgttcaggc tgatgtctta cggcagattt tgcccattct ggtaatttgt atcggcctct
    10441 atttcttgct gatgccaaag ctaggtgaag aagaccgcca gcgccggatg tacggtttac
    10501 ccttcgcgtt aatagccggt ggctgcgtcg gtttttatga tggattcttt ggcccggctg
    10561 ccgggtcgtt ttacgcgctg gccttcgtta cgctgtgcgg atttaacctc gccaaagcca
    10621 cggctcacgc caaattactc aacgcaacgt caaacatcgg cggtttactg ctgtttattc
    10681 tcggcggcaa agtgatttgg gcgacgggct ttgtcatgct ggtggggcag ttcctcggcg
    10741 cgcgcatggg ttcacgactg gtgttgagca aaggacaaaa gctgatccgc ccgatgattg
    10801 ttatcgtctc ggcggtgatg agtgccaaat tactttacga cagccacgga caggagatcc
    10861 tccactggtt ggggatgaac taatgaacag tacacaccac tacgagcagt tgattgaaat
    10921 ttttaatagc tgctttgccg atgattttaa tacccgtctg attaaaggcg acgacgaacc
    10981 gatctatctt cctgctgatg cggaagtacc gtataaccga atcgtctttg ctcatggctt
    11041 ttatgccagc gcaattcatg agatttcgca ctggtgtatt gccgggaaag cgcgccgtga
    11101 gctggttgat ttcggctact ggtattgccc ggacggacgc gatgcccaaa cgcaaagcca
    11161 gtttgaagat gttgaagtga agccgcaggc gctcgactgg ttgttctgtg tggcggcggg
    11221 atatccgttt aacgtcagtt gcgacaatct ggaaggggat ttcgaaccgg atcgtgtggt
    11281 gtttcaacgg cgagtacatg cgcaggtgat ggattatctg acaaatggca ttccggaacg
    11341 tccggcacgc ttcattaaag cactacaaaa ttattatcac acgccggaac ttacggcgga
    11401 acagttcccg tggccggaag cgctcaactg aagccagcgc cacgttttac aatgaggaaa
    11461 gaagatgatc gcggagtttg aatcacgcat tctggcatta atcgacggta tggttgacca
    11521 tgccagtgat gatgagttgt ttgccagtgg gtatttgcgt ggccacctga cattagccat
    11581 cgcagaactg gaaagtggtg atgaccactc cgctcaggcg gtgcatacga ccgttagcca
    11641 gagtctggaa aaagccattg gtgctggtga attgtcgccg cgtgaccagg cgctggtgac
    11701 cgatatgtgg gaaaacctgt ttcagcaggc gtcacagcag taagttgcgg cgtctggagc
    11761 agcatgcctg atgcgacgct tatcgcgtct tatcaggcct acacgtcaca cgtaggtcgg
    11821 ataaggcgtt cacgccgcat ccggcaaaca ctgcgagagc agattacccc gccttaaccg
    11881 ctttaccctt caacaatttc cgcacccata accgattcgg gtttaacgcc gccagcgtac
    11941 tggcatccat cggaatcggt tcgtcgctca tctgcgccgc cagaatctcg gcacacagcg
    12001 gggcagaaca caaaccgcga gaacctaaag ccgcaaacat aaagagatcg tcaaaaaccg
    12061 gcgcgcttac cgcctcatct ttctgctccg ccaacgacgc atattccacg agtgttgcct
    12121 cataatcggg aacattgcct accattggca gatgatcgcg ggtggcacaa cgcacaccgc
    12181 agcgcgcctc tttatcactg acatcaacct cttttgccca ctgtgcctgc gggaaacaat
    12241 caatcaaccg ctggcgattc tgctgctgat cgtcctcact gtacgccgta tcttcgctgc
    12301 cgcgatgata actggcacca atacaatgat gttgattcgc cggattttgt ggcgtgagat
    12361 aaccgtcata gcacagcacc tgcttcagct ctgccaattc cggcgttgtc ggaatatggc
    12421 tgacctgccc ggcaaccgaa tacaccggga gagtcgacgt ttggctgaat cggctgattt
    12481 gatgcccgtt cgccagtacc actacgctgt gtgttgcttg ctgatctcct gcaaaattca
    12541 acaaccaaca gtcatcctta cgggataaat tctgtaactg atattgataa taaatctgca
    12601 aaccctgctg ttgcgccagt tccagcacat tacgggtcag ttctgctggg cacagccaac
    12661 caccttgcgg ataagtaatg ccgctgcaat ttgtcgcaac gcccgtaatt tgttcaaccg
    12721 catttgcctc aacggctaca gccagttctg cgggtaaatc cattgacaac atctgtgcga
    12781 ttttatgctg gcttttctca tcccagccta actgcgtgac gccgcaccag tcatgatcaa
    12841 atttaacggg taattggtcg taaaaccgac gagcaaaagt aaacgcatta gagaaaaagc
    12901 ggtttagcgc ctcatcgtgt ttgcttaata acggatacag cgccccctgg cgattgccgg
    12961 aagcacccag tgcgggggcc tcatccgcgc aataaagcgt tacctgccag ccgcgccgta
    13021 atagcgccag cgacaacaac gcgctagcaa taccaccgcc gataatcgcc gcttcccgtt
    13081 tgctgctgcc cgtgcggtta aaccacggcg cggagcaggg gagcggtaat gtctgttcca
    13141 tcaccccgca aagcatttcc cgtttgcgcc caaagccctt acgtttttgc atcgtgaatc
    13201 cggcgtcctg caaaccgcgg cggacaaaac cggcagacgt aaatgtcgcc agcgtgccgc
    13261 ccggacgcgc caaccttgcc atggcgttaa acagattttg cgtccacata tccgggtttt
    13321 tcgctggcgc aaagccgtcc agaaaccagg catctacttt ttgatttagc gaatcgtcca
    13381 gttggctggt cagttcgtta atatcgccaa accataaatc cagcgtcacg cggcctgcat
    13441 cgagcaataa acgatggcaa ccgggcaagg gcattggcca ctgcgcctga agttgttctg
    13501 cccacggagc cagttccggc cagtgttgat gcgctaaggc taaatccgca cgggtgaggg
    13561 gaaatttctc aaaactaatg aaatgtaagc gttgtaattg cgcttgcgga tgcgcttcgc
    13621 gaaactgatc aaatgcctgc catagcgtca ggaagtttaa tccggtgccg aagccgctct
    13681 ctgctaccac aaacagagga tgtggatgct caggaaagcg tacctctaat tggttgcctc
    13741 ccagaaaaac ataacgcgtc tcttccagcc cgttatcgtt ggaaaaatag acatcgtcaa
    13801 aatctcggga aacaggtgta ccctcagcat taaattcgag gttggcaggt tgtatggagt
    13861 agtgtttcac gtaagttact cgtcttacag gcggtggctc gatcttagcg atgtgtgtaa
    13921 ggctgcgcaa atttctctat taaatggctg atcggacttg ttcggcgtac aagtgtacgc
    13981 tattgtgcat tcgaaactta ctctatgtgc gacttacaga ggtattgaat gaaacgtgca
    14041 gtgattactg gcctgggcat tgtttccagc atcggtaata accagcagga agtcctggca
    14101 tctctgcgtg aaggacgttc agggatcact ttctctcagg agctgaagga ttccggcatg
    14161 cgtagccacg tctggggcaa cgtaaaactg gataccactg gcctcattga ccgcaaagtt
    14221 gtgcgcttta tgagcgacgc atccatttat gcattccttt ctatggagca ggcaatcgct
    14281 gatgcgggcc tctctccgga agcttaccag aataacccgc gcgttggcct gattgcaggt
    14341 tccggcggcg gctccccgcg tttccaggtg ttcggcgctg acgcaatgcg cggcccgcgc
    14401 ggcctgaaag cggttggccc gtatgtggtc accaaagcga tggcatccgg cgtttctgcc
    14461 tgcctcgcca ccccgtttaa aattcatggc gttaactact ccatcagctc cgcgtgtgcg
    14521 acttccgcac actgtatcgg taacgcagta gagcagatcc aactgggcaa acaggacatc
    14581 gtgtttgctg gcggcggcga agagctgtgc tgggaaatgg cttgcgaatt cgacgcaatg
    14641 ggtgcgctgt ctactaaata caacgacacc ccggaaaaag cctcccgtac ttacgacgct
    14701 caccgtgacg gtttcgttat cgctggcggc ggcggtatgg tagtggttga agagctggaa
    14761 cacgcgctgg cgcgtggtgc tcacatctat gctgaaatcg ttggctacgg cgcaacctct
    14821 gatggtgcag acatggttgc tccgtctggc gaaggcgcag tacgctgcat gaagatggcg
    14881 atgcatggcg ttgatacccc aatcgattac ctgaactccc acggtacttc gactccggtt
    14941 ggcgacgtga aagagctggc agctatccgt gaagtgttcg gcgataagag cccggcgatt
    15001 tctgcaacca aagccatgac cggtcactct ctgggcgctg ctggcgtaca ggaagctatc
    15061 tactctctgc tgatgctgga acacggcttt atcgccccga gcatcaacat tgaagagctg
    15121 gacgagcagg ctgcaggtct gaacatcgtg accgaaacga ccgatcgcga actgaccacc
    15181 gttatgtcta acagcttcgg cttcggcggc accaacgcca cgctggtaat gcgcaagctg
    15241 aaagattaat tcgccgtagg tcgggtaagg cgcgccagcg tcgcatccga cgttacgcgc
    15301 caatgcggcc tccggcacta acacaaaagg gaacccgatg gttccctttt tcacatcatt
    15361 gacaatcgcc gcctgttcca ggcaaacttc ccgctttgtc gatttccttc tgaaaagacg
    15421 tacgcgttaa atcctgccaa cgcactgtaa ccctgaaacc agagagatga gacggggata
    15481 ctcctcgcct tgcgctgcat tctggagtaa tgcatgactg ctgtaagcca aaccgaaaca
    15541 cgatcttctg ccaatttttc gctcttccgc atcgcttttg cggtttttct cacctacatg
    15601 accgtagggc tgccgttgcc ggttatcccg ctgtttgttc atcatgatct gggctatggc
    15661 aataccatgg tcgggattgc cgtcgggatt cagtttctgg ctacggtgct gacgcgtggc
    15721 tatgccgggc gactggccga tcaatatggc gcaaaacgtt cggcgcttca ggggatgtta
    15781 gcttgtggtc tggctggcgg cgcgttgctg ctggcggcga ttttgcctgt ctccgcaccg
    15841 ttcaaatttg ccctgttggt catcgggcgt ttgattcttg gctttggtga aagccagtta
    15901 ctgacaggcg ctctgacctg ggggttaggc atcgtagggc caaaacactc tggcaaagtg
    15961 atgtcatgga atggaatggc gatttacggt gccctcgctg ttggtgctcc gcttggcctg
    16021 ttgattcata gccattacgg ttttgccgca ctggcgatca ccacaatggt attaccctta
    16081 ctggcgtggg cctgtaacgg cacagtgcgc aaagtaccgg ccctggcggg agaacgtcca
    16141 tcgctgtgga gcgttgtcgg gcttatctgg aaaccagggt taggtctggc actacaaggc
    16201 gttggttttg ctgttatcgg gactttcgtt tcgctctact ttgccagcaa aggatgggcg
    16261 atggcgggct ttactcttac cgcgtttggc ggcgcatttg tcgtgatgcg cgtcatgttt
    16321 ggctggatgc cggaccgttt tggcggcgtg aaagtggcga ttgtctctct gcttgtagaa
    16381 acggtgggct tgttgctgct ctggcaagcc ccaggtgcat gggtcgcatt agcgggcgcg
    16441 gcgttaaccg gagccggatg ttcgcttatc tttcctgcgc tgggcgtgga ggtggttaaa
    16501 cgcgtcccct cacaagttcg cggcaccgca ctgggcggtt acgccgcgtt tcaggatatc
    16561 gccctcggcg tctccgggcc gctggcggga atgctggcga ccacgtttgg ttactcttcg
    16621 gtatttcttg ccggggcgat ctctgcggtg ctgggtatta ttgtcacgat actgtcattt
    16681 cgtcggggtt aacgaaccag ccagaccagc atcaggataa tcgcgactaa cagtatccac
    16741 agcgcgggac gcgttgccat attttgcaac gtgtccatca tcggtggaaa aggattaagc
    16801 agcggttgca taacacgcgg atcaatccct ttaacccgcc gttgataaag ctgattaaga
    16861 atatcctcgg cctgggcaga agaaagcgat gattgcgcag aaagaccata tttttgctgg
    16921 atatatgccg ataacgccgc cagttcactg gcatctaaag gttgttttag cgtcatctgt
    16981 agtgattcca gcgtcggcgt attttgctgg cttagcgtct gacgcgcctg tagccaggtc
    17041 accagatggt taaacagttt cgctggaatt aactcgccat ctttcacccc ggaaagttcc
    17101 agcatcgatt gccagatctg tttgctgggt tcccccgttg ccgccgcaag tttggtcacc
    17161 agctgtttta gcgcattgtg ctccgccggt aataaaggac ggtcggtcgc ctcgcgctgc
    17221 tgtggttgcg gaataaccat cttcccttcc tgcaacaggg tgagaatggt ttttaattgc
    17281 tccggtgaga gctgattcag cggcgtctga ccaaagttat gacggatata atccgtgacc
    17341 gcctgacgat tattccccag acgtaaatac tcccctaatt gcgctaaaag ctggcgggca
    17401 gaatggcttt tttgcgcggc cagcagacgt tgcgccagat tatgctcagc ggcagggaag
    17461 tgacgcgaaa gcagcggtga atctcccgac agaccaatat cgtgcctgat acccgcccac
    17521 agttctgctc tttgctgttg cgtcagtgag gtcactttcg tcattaagct ttccagcgaa
    17581 gtacgttgct gactggataa aggctgattg cccgtgccag acggcagatt atctccctga
    17641 cctggtggtt gcccaggagg agggccggaa ataggttgta tcattacgta tccttatacc
    17701 tgaaatcttc gcaagtatgc ctggccgcga gattatggca cacttgtccg gttaactctc
    17761 gtctcataca ggtaacacaa acgtgaaaat ccttgttgat gaaaatatgc cttatgcccg
    17821 cgacttattt agccgtttgg gtgaggtgac cgcggttccc gggcgtccaa tccccgtcgc
    17881 tcaactggca gacgcggatg cgctgatggt gcgttcggtc acgaaagtga atgaatcttt
    17941 gctggcagga aaacccatta aatttgttgg cactgccact gcggggaccg accatgtcga
    18001 tgaagcatgg ttgaagcagg cgggaattgg tttttccgct gcacctggct gtaatgcgat
    18061 tgcggtggtg gaatatgttt tctcctccct gctgatgctt gccgaacgcg atggattttc
    18121 actgtacgac cgtacggtgg ggatcgtggg cgttggtaac gttggacgtc gattgcaggc
    18181 gcgactggaa gcgttaggga ttaaaacctt actttgcgat ccgcctcgcg ccgaccgtgg
    18241 ggatgagggt gatttccgct cgctggatga gttagtccag cgcgcggata ttctgacttt
    18301 ccatacgcca ctctttaaag atggtccgta caaaacgcta catctggcgg atgaaaaact
    18361 gatccgtagc ctgaagcccg gagcgattct gattaacgcc tgccgtggcg cagtcgtcga
    18421 taatactgcg ttgctgacct gcctgaatga aggccagaag ttaagcgtag tgctggatgt
    18481 ctgggaaggc gaaccggaac tcaacgtcga gctgctgaaa aaagtggata tcggcacgcc
    18541 gcatatcgca ggctataccc tggaaggtaa agcacgcggt actacgcaag tgtttgaagc
    18601 ttatagcaag tttattgggc atgaacagca cgttgcgctg gatacattac tgcctgcgcc
    18661 agagtttggt cgcattacgc tgcatggccc gctcgatcaa ccgacgctga aaaggctggt
    18721 gcatttggtg tatgatgtgc gccgcgatga cgcaccgctg cgtaaagtcg ccgggatacc
    18781 gggtgagttc gataaactgc gcaaaaacta tcttgagcgc cgtgaatggt catctctgta
    18841 tgtaatttgt gatgacgcca gtgcggcatc attgctgtgt aaactgggtt ttaacgccgt
    18901 tcatcatccg gcacgttaat ctcttcttca tgctctctgc tgtaacattg gcagggagct
    18961 ttgctatttc tggagtaaac caccatgtct gaaggctgga acattgccgt cctgggcgca
    19021 actggcgctg tgggcgaagc cctgcttgaa acgctggctg aacgtcagtt cccggttggg
    19081 gaaatttatg cactggcacg taacgaaagc gcaggcgaac aactgcgctt tggtggtaag
    19141 acaatcaccg tgcaggatgc cgctgaattc gactggacgc aggcgcagct ggcatttttt
    19201 gtcgcaggca aagaagctac cgctgcctgg gttgaagaag cgaccaactc aggttgcctg
    19261 gtgatcgaca gcagtggatt gtttgctctc gaacccgacg taccgctggt ggtgccggaa
    19321 gtaaacccgt ttgtactgac agattaccgg aaccggaatg tcatcgccgt accagacagt
    19381 ctgaccagcc agctgctggc ggcactgaaa ccgttaatcg atcagggcgg tttatcacgt
    19441 atcagcgtta ccagcctgat ttcagcctcc gcccagggca aaaaagcggt cgatgcgtta
    19501 gcggggcaga gtgcgaaatt gctcaacggc attccgattg acgaagaaga tttcttcggg
    19561 cgtcagctgg cgttcaacat gctgccgtta ctgccggata gcgaaggtag cgtgcgtgaa
    19621 gaacgtcgta tcgttgacga agtacgcaaa atcctgcagg acgaagggct gatgatttcg
    19681 gctagcgtcg tccaggcacc ggtattctac ggtcatgccc agatggtcaa ctttgaagct
    19741 ctgcgtccac tggcagcaga agaagcgcgt gatgcgtttg ttcaaggcga agatattgtg
    19801 ctctctgaag agaacgaatt cccaactcag gtaggtgatg cttcgggtac gccgcatctt
    19861 tctgttggct gcgtgcgtaa tgactacggt atgccggagc aagtccagtt ctggtcggtg
    19921 gccgataacg ttcgctttgg cggcgcgctg atggcagtaa aaatcgccga gaaactggtg
    19981 caggagtatc tgtactaatg tccgaccagc aacaaccgcc agtttataaa attgcgctgg
    20041 gcattgagta cgacggcagt aagtattacg gctggcaacg gcagaacgaa gtccgcagtg
    20101 tgcaggagaa gctggaaaag gcgctctccc aggtggcgaa cgaacccatc accgtcttct
    20161 gcgccgggcg tactgacgca ggggtacacg gtaccgggca ggttgtgcat ttcgaaacaa
    20221 ccgcgctgcg caaagacgcg gcgtggacct tgggcgtaaa tgcgaattta cctggtgaca
    20281 tcgctgtgcg ttgggttaaa gctgtacctg atgattttca tgcccgattt agcgccacgg
    20341 ctcgccgtta tcgctacatc atctacaatc atcggctgcg cccggcggta ctgagtaaag
    20401 gggtaaccca tttttacgaa ccgctggacg ctgaacggat gcatcgggct gcgcaatgct
    20461 tgctgggcga gaatgatttc acctcgttcc gtgcggtgca gtgccagtcc cgaaccccgt
    20521 ggcgcaacgt tatgcatatt aatgtcacgc gtcacggtcc ttatgtggtg gtagatatta
    20581 aagcgaatgc ttttgtacat catatggtca ggaatattgt cggcagcctg atggaagtcg
    20641 gtgcccacaa ccagccggag agctggatag cagagttgct ggcggcaaag gacagaacgc
    20701 tggcggcagc aacggcaaaa gcggaagggc tgtatctggt cgcggtggat taccctgacc
    20761 ggtatgatct tccaaaaccg ccaatgggcc cgctatttct ggcggactaa cgagaataat
    20821 gctcggaaca tttcaggctg tagccaacgt agttacagcc tgaaagatga cgagtacaag
    20881 gcataggcaa atatggacct gatttatttc ctcatcgatt ttatcctgca cattgacgtg
    20941 catctggcag agctggtcgc ggagtacggc gtctgggttt atgccatttt gttcttaatt
    21001 ttgttctgtg aaaccggtct ggtggtaacg ccgtttttac cgggtgattc attgctgttt
    21061 gttgccggag cgttggcatc actggaaacc aacgatctca acgtccatat gatggtggtg
    21121 ctgatgctga tcgccgcgat tgtgggtgac gcggtcaatt acactatcgg gcggttgttc
    21181 ggtgaaaagt tgttcagtaa tcccaattcg aaaattttcc gtcgcagtta tctcgacaaa
    21241 acccatcagt tttatgagaa acatggcggc aaaacgatta ttctcgcccg ttttgtgccg
    21301 atcgtcagaa cgttcgcccc gtttgttgcg ggaatgggcc acatgtcgta ccgtcatttc
    21361 gccgcttata acgtgatcgg cgcactgttg tgggtactgc tttttaccta cgcaggctat
    21421 ttcttcggta caatcccgat ggttcaggat aaccttaagc tgctgatcgt cgggattatt
    21481 gtggtttcta ttttgccggg cgtcatcgaa ataatccgtc acaaacgcgc tgcggcacgc
    21541 gccgcaaaat aaaaagtaac tccgcggttc gaccactttt ttatccaaag tttcgggctg
    21601 ttatgtttta atgtgcaaca ttcatggtct gttgggggca aaaatggcat tatgcgtccc
    21661 caaagataaa actggcatcg aaccaggttc agacagaaag gtccctaatg agctggattg
    21721 aacgaattaa aagcaacatt actcccaccc gcaaggcgag cattcctgaa ggggtgtgga
    21781 ctaagtgtga tagctgcggt caggttttat accgcgctga gctggaacgt aatcttgagg
    21841 tctgtccgaa gtgtgaccat cacatgcgta tgacagcgcg taatcgcctg catagcctgt
    21901 tagatgaagg aagccttgtg gagctgggta gcgagcttga gccgaaagat gtgctgaagt
    21961 ttcgtgactc caagaagtat aaagaccgtc tggcatctgc gcagaaagaa accggcgaaa
    22021 aagatgcgct ggtggtgatg aaaggcactc tgtatggaat gccggttgtc gctgcggcat
    22081 tcgagttcgc ctttatgggc ggttcaatgg ggtctgttgt gggtgcacgt ttcgtgcgtg
    22141 ccgttgagca ggcgctggaa gataactgcc cgctgatctg cttctccgcc tctggtggcg
    22201 cacgtatgca ggaagcactg atgtcgctga tgcagatggc gaaaacctct gcggcactgg
    22261 caaaaatgca ggagcgcggc ttgccgtaca tctccgtgct gaccgacccg acgatgggcg
    22321 gtgtttctgc aagtttcgcc atgctgggcg atctcaacat cgctgaaccg aaagcgttaa
    22381 tcggctttgc cggtccgcgt gttatcgaac agaccgttcg cgaaaaactg ccgcctggat
    22441 tccagcgcag tgaattcctg atcgagaaag gcgcgatcga catgatcgtc cgtcgtccgg
    22501 aaatgcgcct gaaactggcg agcattctgg cgaagttgat gaatctgcca gcgccgaatc
    22561 ctgaagcgcc gcgtgaaggc gtagtggtac ccccggtacc ggatcaggaa cctgaggcct
    22621 gataactgat aagggcaggg ccactggctc tgcccttttg ctattctcac cgtaacgaat
    22681 cagcggatac catgattatc aaacgcactc ctcaagccgc gtcgcctctg gcttcgtggc
    22741 tttcttatct ggaaaacctg cacagtaaaa ctatcgatct cggccttgag cgcgtgagcc
    22801 tggtcgcggc gcgtcttggc gtcctgaaac cagcgccatt tgtgtttacc gttgcgggta
    22861 cgaatggcaa aggcaccacc tgccgtacgc tggagtcgat tctgatggcg gcagggtaca
    22921 aagtgggcgt ctacagttcg cctcatctgg tgcgttatac cgagcgcgta cgtgtgcagg
    22981 gccaggaatt gccggaatcg gcccacaccg cctcttttgc ggagattgaa tcggcacgcg
    23041 gtgatatttc cctgacctat ttcgagtacg gtacgctgtc ggcgttgtgg ctgttcaagc
    23101 aggcacaact tgacgtggtg attctggaag tagggctggg cggtcgtctg gacgcaacca
    23161 atattgtcga cgccgatgtc gcggtagtaa ccagtattgc gctggatcat accgactggc
    23221 tgggtccaga tcgcgaaagt attggtcgcg agaaagcagg catcttccgc agcgaaaaac
    23281 cggcaattgt cggtgagccg gaaatgcctt ctaccattgc tgatgtggcg caggaaaaag
    23341 gtgcactgtt acaacgtcgg ggcgttgagt ggaactattc cgtcaccgat catgactggg
    23401 cgtttagcga tgctcacggc acgctggaaa atctgccgtt gccgcttgtc ccgcaaccga
    23461 atgccgcaac agcgctggcg gcactgcgtg ccagcgggct ggaagtcagt gaaaatgcca
    23521 ttcgcgacgg gattgccagc gcaattttgc cgggacgttt ccagattgtg agcgagtcgc
    23581 cacgcgttat ttttgatgtc gcgcataatc cacatgcggc ggaatatctc accgggcgta
    23641 tgaaagcgct accgaaaaac gggcgcgtgc tggcggttat cggtatgcta catgataaag
    23701 atattgccgg aactctggcc tggttgaaaa gcgtggttga tgactggtat tgtgcgccac
    23761 tggaagggcc gcgcggtgcc acggcagaac aactgcttga gcatttgggt aacggcaaat
    23821 catttgatag cgttgcgcag gcatgggatg ccgcaatggc ggacgctaaa gcggaagaca
    23881 ccgtgctggt gtgtggttct ttccacacgg tcgcacatgt catggaagtg attgacgcga
    23941 ggagaagcgg tggcaagtaa gtttcagaat cggttagtgg gcacgatcgt gctggtggcg
    24001 ctgggggtga ttgtacttcc agggctgctg gacgggcaga aaaaacatta tcaggatgag
    24061 ttcgcggcta tcccgctggt gccgaaagcg ggcgatcgtg atgagcctga tatgatgcca
    24121 gccgccaccc aggcgttacc gacgcagccg ccggaaggcg cagcggaaga ggtgcgggca
    24181 ggtgatgccg cagcaccgtc gctcgatccg gccactattg cagccaataa caccgagttt
    24241 gaaccggaac ctgcaccggt cgccccaccg aagccgaaac cggtggagcc gcctaaacca
    24301 aaggttgaag caccacctgc gccgaagcca gaaccgaagc cggtcgtgga agaaaaagct
    24361 gcaccgacgg gtaaagccta tgttgtgcaa ctgggtgcgc tgaaaaatgc cgataaagtg
    24421 aatgagattg tcggtaagct gcgcggtgcc ggttatcggg tttatacgtc gccatccacg
    24481 ccagtgcagg gtaaaattac ccgtattctg gttgggccgg atgcctcgaa agataagctg
    24541 aaaggttcgc tgggtgagtt gaagcaactt tctggcttaa gtggcgtggt aatgggctat
    24601 acgccgaatt aatacggtct tgcctgatgc gacgctggcg cgtcttatca ggcctacgca
    24661 ggggtagaac cgtaggtcgg ataaggcgtt tacgccgcat ccgacacgca ttgcccgatg
    24721 ccgcaaaggc ataaaaagtc gatggcgttg aatatttttt cagcgccatt tttattgatg
    24781 cgcgggaagg aaatccctac gcaaacgttt tctttttctg ttagaatgcg ccccgaacag
    24841 gatgacaggg cgtaaaatcg tgggacacat atggtctgga ttgattacgc cataatcgcg
    24901 gtgattgctt tttcctctct ggttagcctg atccgcggct ttgttcgtga agcgttatcg
    24961 ctggtgacat ggggttgtgc tttctttgtt gccagtcatt actacactta cctgtcagtc
    25021 tggtttacgg gctttgaaga cgaactggtt cgaaatggga ttgccatcgc ggtactgttt
    25081 atcgctaccc tgatcgttgg tgctatcgtg aacttcgtga taggccagtt ggtggagaaa
    25141 acggggttgt caggcaccga tcgggtgctg ggcgtctgtt tcggtgcgtt gcgcggtgtg
    25201 ttgattgttg ctgccattct cttctttctc gactccttta ccggggtgtc gaaaagcgaa
    25261 gactggagca aatcacagct gatcccgcaa ttcagtttta tcatcagatg gttttttgat
    25321 tatctgcaaa gctcgtcaag tttcttgccc agagcgtaag tgctctgaga tgtggcttaa
    25381 cgaggaaaaa gacgtatgtg cggtattgtc ggtatcgccg gtgttatgcc ggttaaccag
    25441 tcgatttatg atgccttaac ggtgcttcag catcgcggtc aggatgccgc cggcatcatc
    25501 accatagatg ccaataactg cttccgtttg cgtaaagcga acgggctggt gagcgatgta
    25561 tttgaagctc gccatatgca gcgtttgcag ggcaatatgg gcattggtca tgtgcgttac
    25621 cccacggctg gcagctccag cgcctctgaa gcgcagccgt tttacgttaa ctccccgtat
    25681 ggcattacgc ttgcccacaa cggcaatctg accaacgctc acgagttgcg taaaaaactg
    25741 tttgaagaaa aacgccgcca catcaacacc acttccgact cggaaattct gcttaatatc
    25801 ttcgccagcg agctggacaa cttccgccac tacccgctgg aagccgacaa tattttcgct
    25861 gccattgctg ccacaaaccg cttaatccgc ggcgcgtatg cctgtgtggc gatgattatc
    25921 ggccacggta tggttgcttt ccgcgatcca aacgggattc gtccgctggt actgggaaaa
    25981 cgtgatattg acgagaaccg tacagaatat atggtcgctt ccgaaagcgt agcgctcgat
    26041 acgctgggct ttgatttcct gcgtgacgtc gcgccgggcg aagcgattta catcactgaa
    26101 gaagggcagt tgtttacccg tcaatgtgct gacaatccgg tcagcaatcc gtgcctgttt
    26161 gagtatgtat actttgcccg cccggactcg tttatcgaca aaatttccgt ttacagcgcg
    26221 cgtgtgaata tgggcacgaa actgggcgag aaaattgccc gcgaatggga agatctggat
    26281 atcgacgtgg tgatcccgat cccagaaacc tcgtgtgata tcgcgctgga aattgctcgt
    26341 attctgggca aaccgtaccg ccagggcttc gttaaaaacc gctatgttgg ccgcaccttt
    26401 atcatgccgg gccagcagct gcgtcgtaag tccgtgcgcc gtaaactgaa tgccaaccgc
    26461 gccgagttcc gcgataaaaa cgtcctgctg gtcgacgact ccatcgtccg tggcaccact
    26521 tctgagcaga ttatcgagat ggcacgcgaa gccggagcga agaaagtgta cctcgcttct
    26581 gcggcaccgg aaattcgctt cccgaacgtt tatggtattg atatgccgag cgccacggaa
    26641 ctgatcgctc acggtcgcga agttgatgaa attcgccaga tcatcggtgc tgacgggttg
    26701 attttccagg atctgaacga tctgatcgac gccgttcgcg ctgaaaatcc ggatatccag
    26761 cagtttgaat gctcggtgtt caacggcgtc tacgtcacca aagatgttga tcagggctac
    26821 ctcgatttcc tcgatacgtt acgtaatgat gacgccaaag cagtgcaacg tcagaacgaa
    26881 gtggaaaatc tcgaaatgca taacgaagga tgatgccttc gctgagggtg ccggtctggc
    26941 accctgactt gcaactcccg ccgaaatcct gcaaagtctg cctgcaagtc tgacagggca
    27001 actatttatg aaacgactca ttgtaggcat cagcggtgcc agcggcgcga tttatggcgt
    27061 gcgcttatta caggttctgc gcgatgtcac agatatcgaa acgcatctgg tgatgagcca
    27121 ggcagcgcgc cagaccttat ccctcgaaac ggatttttct ctgcgcgaag tgcaggcatt
    27181 agccgatgtc acgcacgatg cgcgcgatat tgccgccagc atctcttccg gttctttcca
    27241 gacgctgggg atggtgattt taccctgttc aatcaaaacc ctttccggca ttgtccatag
    27301 ctatactgat ggcttactga cccgtgcggc agatgtggtg ctgaaagagc gtcgcccgtt
    27361 ggtgctctgc gtgcgtgaaa caccattgca cttaggccat ctgcgtttaa tgactcaggc
    27421 ggcagaaatc ggtgcggtga ttatgcctcc cgttccggcg ttttatcatc gcccgcaatc
    27481 ccttgatgat gtgataaatc agacggttaa tcgtgttctt gaccagtttg cgataaccct
    27541 tcctgaagat ctctttgccc gctggcaggg cgcataactc cgctgttgcc ctgtttcagg
    27601 gcaattttgc aaccgcgatc aaatcctcga cattttgttt ctgccattca atcgaaacgc
    27661 tgcgattcaa ccgctatacc tgctatcttc aacttcagga caataatgca acgtcttatt
    27721 aacatattta acgttgaatg ttactgttgt cgtcaagatg gcataagacc tgcatgaaag
    27781 agcctgcaaa cacacaacac aatacacaac ataaaaaagc cattttcact tgagggttat
    27841 gtatgaagaa gtcgattctc gctctgtctt tgttagtcgg tctctccaca gcggcttcca
    27901 gctatgcggc gctaccggag acggtacgta tcggaaccga taccacctac gcaccgttct
    27961 catcgaaaga tgctaaaggt gattttgttg gctttgatat cgatctcggt aacgagatgt
    28021 gcaaacggat gcaggtgaaa tgtacctggg ttgccagtga ctttgacgcg ctgatcccct
    28081 cactgaaagc gaaaaaaatc gacgctatta tttcgtcgct ttccattacc gataaacgtc
    28141 agcaggagat tgccttctcc gacaagctgt acgccgcaga ttctcgtttg attgcggcca
    28201 aaggttcacc gattcagcca acgctggatt cactgaaagg taaacatgtt ggtgtgctgc
    28261 agggatcaac ccaggaagct tacgctaacg agacctggcg tagtaaaggc gtggatgtgg
    28321 tggcctatgc caaccaggat ttggtctatt ccgatctggc tgcaggacgt ctggatgctg
    28381 cgttacaaga tgaagttgct gccagcgaag gattcctcaa gcaacctgct ggtaaagatt
    28441 tcgcctttgc tggctcatca gtaaaagaca aaaaatactt cggtgatggc accggtgtag
    28501 ggctacgtaa agatgatgct gaactgacgg ctgccttcaa taaggcgctt ggcgagctgc
    28561 gtcaggacgg cacctacgac aagatggcga aaaagtattt cgactttaat gtctacggtg
    28621 actgatacgt cgctgggaag ctgtacctga tggaatgatc atcatggtgc acgccaggtt
    28681 tgttgcacta tcgtggtgca ttgaaatgca tacttaagca tttttaatga aaaataatac
    28741 gtctaacggg gcgggatatt ttgccttgat ggtcaatttt atggcacgat aagtgtaaca
    28801 aacctgtaaa tattccctat aaaaagactg tcagttgagg acattatgaa aaaactggtg
    28861 ctatcgctct ctctggttct ggccttctcc agcgcaactg cggcgtttgc tgcgattccg
    28921 caaaacatcc gcatcggtac cgacccgacc tatgcgccat ttgaatcaaa aaattcacaa
    28981 ggcgaactgg ttggcttcga tatcgatctg gcaaaggaat tatgcaaacg catcaatacg
    29041 caatgtacgt ttgtcgaaaa tccgctggat gcgttaatcc cgtccttaaa agcgaagaag
    29101 attgacgcca tcatgtcatc gctttccatt acggaaaaac gtcagcaaga aatagccttc
    29161 accgacaaac tgtacgctgc cgattctcgt ttggtggtgg cgaaaaattc tgacattcag
    29221 ccgacagtcg agtcgctgaa aggcaaacgg gtaggcgtat tgcagggcac cacccaggag
    29281 acgttcggta atgaacattg ggcaccaaaa ggcattgaaa tcgtctcgta tcaggggcag
    29341 gacaacattt attctgacct gactgccgga cgtattgatg ccgcgttcca ggatgaggtc
    29401 gctgccagcg aaggtttcct caaacaacct gtcggtaaag attacaaatt cggtggcccg
    29461 tctgttaaag atgaaaaact gtttggcgta gggaccggca tgggcctgcg taaagaagat
    29521 aacgaactgc gcgaagcact gaacaaagcc tttgccgaaa tgcgcgctga cggtacttac
    29581 gagaaattag cgaaaaagta cttcgatttt gatgtttatg gtggctaatc gccatcggtg
    29641 aaagaaagcc cgctcccttc gggtaaccgg agggagacaa gaggcggtaa ttcaccacac
    29701 acgacaggac aggcagcatg ttgtatgggt tttcaggtgt tattttacag ggtgcgctcg
    29761 tcacgctgga gctggctatc agctctgtag tgctcgctgt aatcatcggt ttaattggcg
    29821 ctggcggtaa gctctcgcaa aatcggcttt cggggctgat tttcgaaggg tacaccacgc
    29881 tgattcgtgg cgtgccggac ttagtgttga tgctgctgat tttctacggt ttgcagattg
    29941 cgctaaacac ggtgacggag gcgatgggcg tcgggcagat tgatatcgat ccgatggtcg
    30001 ctggtattat cactctcggt tttatctacg gtgcttattt taccgaaacg ttccgtggtg
    30061 cttttatggc agtgccgaaa ggacatatag aggcggcgac ggcgttcggt tttactcgtg
    30121 ggcaagtgtt tcggcggatc atgtttccgt cgatgatgcg ttacgccctg ccaggcattg
    30181 gcaacaactg gcaggtgatc ctcaaatcta ccgcactggt ttcgttactc ggcctggaag
    30241 atgtggtcaa agccacccaa ctggcaggca aaagtacctg ggaaccgttc tatttcgcca
    30301 tcgtctgtgg cgtgatttac ctggttttca ccactgtttc caatggtgtg ctgctgttcc
    30361 ttgagcgccg ctactccgtg ggtgtgaaga gggctgacct gtgatcgaaa tcttacatga
    30421 atactggaaa ccgctgctgt ggaccgacgg ttatcgcttt actggtgtgg cgatcactct
    30481 gtggctgctt attttgtcgg tagtgatagg cggagtcctg gcgctgtttc tggcgattgg
    30541 tcgtgtctcc agtaataaat acatccagtt tccaatctgg ttatttacct atatttttcg
    30601 cggtacgccg ctgtatgttc agttgctggt gttctattcc ggcatgtaca cgcttgagat
    30661 tgttaaggga accgaattcc ttaacgcttt cttccgcagt ggcctgaact gtaccgtgct
    30721 ggcgctgacg cttaacacct gcgcttacac taccgagatt tttgctgggg caatccgttc
    30781 ggttccgcat ggggaaattg aagccgccag agcctatggc ttctcgactt ttaaaatgta
    30841 tcgctgcatt attttgcctt ctgcgctgcg tattgcgtta ccggcataca gcaacgaagt
    30901 gatcctgatg ctgcactcta ctgcgttggc atttactgcc acggtgccgg atctgctgaa
    30961 aatagcccgc gatattaacg ccgccacgta tcaacctttt accgccttcg gcattgccgc
    31021 ggtgctctat ttaatcatct cttatgtcct gatcagcctc tttcgcagag cggaaaaacg
    31081 ctggttgcag catgtgaaac cttcttcaac gcactgagaa tacgatgtcc gagaataaat
    31141 taaacgttat cgatttgcac aaacgctacg gcgaacatga agtgctgaaa ggggtatcac
    31201 tgcaagcgaa tgccggagat gtaataagca tcatcggatc gtcgggatcg gggaaaagta
    31261 cctttctgcg ctgcattaac ttcctcgaaa aaccgagtga agggtcgatc gtggtcaatg
    31321 gccagacgat caatctggtg cgcgacaaag acggtcaact caaagtcgcc gataaaaatc
    31381 aactgcgctt actgcgcaca cgcctgacga tggtattcca gcacttcaat ctctggagcc
    31441 atatgacggt gctggaaaac gtcatggaag cgccgattca ggtgttgggc ctgagcaagc
    31501 aggaagcgcg cgagcgggcg gtgaagtatc tggcaaaagt cgggatagac gaacgtgcgc
    31561 aggggaaata tccggtgcat ctttccggcg gtcagcaaca gcgtgtttct atcgcgcggg
    31621 cgctggcgat ggaaccggaa gttttactgt ttgatgaacc tacctcggcg ctcgatcctg
    31681 aactggtagg cgaagtgttg cgtattatgc agcaactggc agaagagggg aaaaccatgg
    31741 tggtagtgac tcacgaaatg ggctttgctc gccatgtttc tactcatgtc attttcctcc
    31801 atcaggggaa aatagaagaa gagggcgcgc cggagcagtt atttggcaac ccgcaaagcc
    31861 ctcgtctgca acggttcctt aagggatcgc tgaaataatt tcctctccgg tggctaacgc
    31921 tgccggagta ttttcatggg gaatttgcga gtcagcttcc gctgaaatgt aaaagttaca
    31981 gtccgctaaa aatacttctg aattcgctgt ccaaagataa aaactgcctg ctgcattggg
    32041 tgttaatcgt ggttattgtc gcgtcatctt aaatttgagg ggtgacggaa cgccatgaca
    32101 atatcgacaa cttccacgcc gcatgatgcg gtatttaaat cttttttacg ccatccagac
    32161 accgcgcggg attttattga tattcatctt cccgcgccgc tgcgcaaact gtgtgattta
    32221 acgacgctta aactggaacc aaacagtttt attgatgaag acctgcggca atattattcc
    32281 gacctcttgt ggtctgtgaa aacgcaggag ggagtgggtt atatttatgt agtgatagag
    32341 caccaaagta agccggaaga attaatggct tttcgcatga tgcgttattc cattgcggca
    32401 atgcaaaacc atcttgatgc gggctataaa gagcttccat tggtgctccc gatgctgttt
    32461 tatcatggtt gcagaagtcc ttatccttat tcactctgct ggcttgatga atttgccgag
    32521 cctgctatag cccgcaaaat atattcatcg gcttttccgt tggtggatat taccgtggtg
    32581 ccggatgacg agattatgca acaccgcaaa atggcgctgt tggagttaat tcagaaacat
    32641 attcgtcagc gcgatctgtt gggattagtc gaccaaattg tttcgctgct agttacaggg
    32701 aacactaatg acagacagct aaaagccctg tttaattacg tattacaaac aggggatgcc
    32761 cagcgttttc gtgcatttat tggtgagata gcggaacgcg caccacaaga aaaggagaaa
    32821 ctgatgacca ttgctgacag attacgtgaa gaaggcgcaa tgcagggcaa acacgaagaa
    32881 gccctgcgta ttgctcagga gatgctggat agaggtttag acagagagtt agttatgatg
    32941 gtgacccgac tttcaccaga cgatcttatc gcgcaaagcc actaatcctg taacaccggg
    33001 agttaactgg cggatgtttg ctgtaaacca catcagcgaa cgacatccgc cagcgcctct
    33061 tctaaatcgt accagcgaaa cgcaaaaccc gcttcttcca gccgtttagg cagcgcgcgt
    33121 tgtccaccta ataccagtac tgaagattcg cccattaaca gtcgaatggc ggtcgcgggg
    33181 acgcgcaaaa tggccgggcg atgcagcgca tgaccgagcg catgggcaaa ttgttcattg
    33241 cgtaccgggt agggcgaaac catattaaat ggcccgcgca gctcgttatc cagcagccag
    33301 agaataccgt tgaccatatc atcaatatga atccaggcca gatactgccg accagagcca
    33361 atcggcccgc ccaggccaag acgaaacggc ggcagcattt taccgagaat accgccatcc
    33421 ggtgccagca ctacaccggt acgcagcagg cacactcgcg ttttgtcact ttgcgcccgg
    33481 caggcaattt cttcccagcg agcgcagagt ttatgggtaa attcgttatg cggcggttcc
    33541 tcttcggtaa ccaccacttc acctaagtca ccataatagc ccgttgccga gccggaaatg
    33601 agtaccgacg gtggcgtgtc gctggcatta atcaaatcga ccagtttttg cgtgatattc
    33661 cagcggcttt ggcagagacg ctctttttgc tcgtgagtcc agcgtttatc agcaatcggt
    33721 tctccggcca ggttgattac cgcatcaacg ccgttgaggt tgctttgatc ggcaagccct
    33781 tgccatagtg tcacccgagg gccgagaacg gaactggctt tctgcgggtt acgcgtcact
    33841 accgtaattt gatggcccag ctccagcaaa cgcggaatca aatggcgacc aattaatcct
    33901 gtccctccgg tgatcactat gttcatgcag cctcccgata tggcgattaa cgctgccagc
    33961 ttaaggtcat ggataccgaa tcggcgtagc gcagcgcgtg cagtttatcg atctccactt
    34021 cagcatacgt cacccagtga tgttcacgtg cgatatcgag cacatcctga gttaattttt
    34081 ccagcaaaga gaaacggtta ttctctacat gctgaataat gtttttcgtt acggtgcgat
    34141 aattcagcgc atcgttgata tcttcgctag tgcgcgcttt atcggcgggg tagtggatcg
    34201 tcacattgat aacaatatcc tgacggttgt taatttcttc ttccttaatt ccgataaacg
    34261 tacgcaaacg aaggttcttt atacgaataa tagcggcagg ttgtgccatt gcaggttctc
    34321 cgttgtttta cttaggatga aataatacac gagaacctgt ttctgttaac tatccgaacg
    34381 ctcatcaccg agttgtgctt ttagcagtgc ctgcccggtg gcagggcgcg aacggatccg
    34441 ctcatgccag ttcttgactg ccggatacat tgctaggtca attcgctggc gagtccaggc
    34501 attaacccac ggccagcagg caatatccgc aatgctgtag ttctcgcctc ccagccaggg
    34561 cgagttttcc agccgcttgt tcagtacatg gtaaagacgc tgagtttcaa cctgataacg
    34621 ttcaatagcg taaggaatgg tttggggggc tgcgtgatta aaatgatgat tttgcccaag
    34681 catcggcccc agtccgccta cctgccagaa taaccactgt aatgtggcgg cgcgctcacg
    34741 cgtttcatga ctcaaaaaga gtcctgtttt ctcagccaga tacaacaaaa tggcaccaga
    34801 ctcaaagagg cttagcggtt cgccgccatc ggcaggagaa tgatcaacaa ttgccggaat
    34861 tttgttgttg ggcgaaatgc gcaaaaattc cggacgaaac tgaccgcctt tccccaggtc
    34921 taccttaatc aagcgataat ccagctctgc ttcttcgaga aacagcgtaa ttttgtgacc
    34981 attgggtgtc ggggcgaaat agagatcgat cattgcagct ccggttgttt aatcatctga
    35041 acaccacaag tatagaaagc gcggcgactt acgtgagtat tcgtcacgtg acagtgacaa
    35101 aaaggctcta tagtttgata gccagccccc tttattgccg aggacataat gagtaaaccc
    35161 gctatcacgc tttggtcaga tgcccacttt ttctcccctt atgtgttatc cgcctgggtg
    35221 gcgttgcagg aaaaaggcct gtcgtttcat atcaagacca tcgacctcga cagcggtgaa
    35281 catttgcagc cgacgtggca aggttacggt cagacacgcc gtgtgccgtt attacaaatc
    35341 gatgattttg agttgagtga atcttctgcc attgcggagt atctggaaga tcgatttgcg
    35401 ccaccgacct gggaacgtat ttatccgctt gatttagaaa atcgtgcgcg tgcacgacag
    35461 attcaggcct ggctgcgcag cgatctgatg cccatccgcg aagagcgtcc gacggatgtt
    35521 gtctttgcgg gggcgaaaaa agcgccacta acggccgagg gaaaagccag tgcagagaaa
    35581 ctgttcgcga tggcagaaca tttgttagta ctgggtcagc cgaatttatt tggtgaatgg
    35641 tgcattgctg atactgatct ggcgctaatg attaaccgcc tggtactaca tggcgatgag
    35701 gtgccagaac gcctggtgga ttatgcaaca ttccagtggc agcgagcgtc tgtccagcgt
    35761 tttattgcac tttcggcgaa gcaatctggc tgatagcaac gacagaatcc agtatcatag
    35821 cttacgtttt ttcgacgagg agtgagtgat gaaactgatg tttgcatcgg acattcatgg
    35881 gtcgttaccg gcgacggaac gtgttctgga gttgtttgcc caaagcggtg cccagtggct
    35941 ggtgatcctt ggcgacgtgt tgaatcacgg cccgcgtaat gctttaccgg agggttacgc
    36001 gccagccaaa gtcgctgaac ggcttaatga agtggcacat aaggttatcg ctgtgcgcgg
    36061 caactgcgac agcgaagtgg atcaaatgct gctgcatttc ccgataaccg cgccgtggca
    36121 acaggtatta ctggaaaaac aacgtctgtt tttgacgcat ggtcatcttt ttggcccgga
    36181 aaatctgcct gctttaaacc agaacgatgt gctggtgtac ggtcataccc atctgccagt
    36241 ggcagaacag cggggggaga ttttccactt caaccccggc tcggtgagta ttccgaaagg
    36301 cggtaatccg gcgagttatg gcatgctgga taatgacgta cttagtgtaa tcgcactcaa
    36361 tgatcaaagt atcattgcgc aggtcgcgat taatccgtaa tttacccaca actcaaaatg
    36421 cgccgtaaga gcgccagaaa aagaaggttt cctgataatg gaacagcgtc gtttggcaag
    36481 tactgaatgg gtggatattg tcaatgaaga gaacgaagtc attgcacaag ccagccggga
    36541 acaaatgcgg gcacagtgtc tgcgtcatcg tgcaacttac atcgtcgtgc atgatggcat
    36601 gggcaaaatt ctggtccagc gtcgtaccga gacaaaagac tttttacccg gcatgttaga
    36661 tgcgaccgca ggcggtgtag tccaggccga tgagcaactg ctggaatccg cgcgtcgcga
    36721 agcggaagaa gagttgggca ttgccggtgt cccctttgcc gagcacgggc agttctattt
    36781 cgaagataaa aattgccgtg tctggggcgc attgttcagc tgcgtctctc acggtccctt
    36841 cgcactacag gaagatgaag tcagtgaagt ttgctggctg acgccggaag aaatcaccgc
    36901 acgctgcgat gagttcactc cagactcgct gaaagcgcta gcgttgtgga tgaagcgcaa
    36961 tgccaaaaat gaagccgtag agactgaaac ggcagaatga aaaaagagcc gcaattgcgg
    37021 ctcttaacat ttttagtggt agcccatcaa ctgagcgccg atcactacga cgctggacat
    37081 aataaacagc agtccaagta gggtcgcgcc caccttcagc cagttacgga agtccaccct
    37141 gcacacaccg agcgttgcca ttaacgacgc tgaggttggg taaatgatgt gactgaagcc
    37201 atcaccaaac tggaacgcca gcacggtaac ctgacggtta acaccgacca gatcgccaag
    37261 cggtgccagt aacggcatgg ttaacgccgc ctgaccagaa ccggacgtca cgaagaaatt
    37321 aaataccgcc tggaagagca acataaacca ggccgcgacc gcgttgtcca gaccgctaat
    37381 ggcattggca atgctgttga ggatggtatt taacacgctg gcatcacccg cttcaccatt
    37441 accgaccagc agcaaaatcc ctttggcgaa acccaccagc agggcagggg cgatcatcat
    37501 tcgcgcccct tcggtaaagg atgaagccat ggtattaacc gtcatgccgt taaggcggaa
    37561 aacaacgccg atgatgccaa tcaccagacc catggtgaag aactggctgg caatttctgg
    37621 aataaaccag gcattaacga tcacgcccca aatcacccag accattacgg cggtcaggac
    37681 aatcaatacc agccagtcac caaaggtaaa cggacgttgt tcaacatcag cctgcttttc
    37741 acgaaagaag cggtcggact catgcacgcg tgacagaaga ggattctttt tcactcgtga
    37801 ggcgtacacc atggtaaaga tcaggccaat cagagtggcg ataacccaca ccacgatgcg
    37861 caacccggag ccagaaagca ccggaacgcc ggcaatcccc tgagcaacga ccacacaaaa
    37921 cgggttcatc cacgaactgg caaaaccgat ttgcgtggca atataggtca ccaggacggt
    37981 ggtaatactg tcatagccca gccggaccat tagcggtgcg atgataatgg caaaggcgac
    38041 ggcctcttct cccataccaa ataccgcgcc gccaagtgaa aacagaataa acagcgcagg
    38101 aataaagaga atttcattcc cgcgggtatg gcgaataagc gccaggatac cgttatcaat
    38161 ggttcctgta cgcatcacaa tgccaaacgc gccgccaatc accagcataa acatgatgat
    38221 gccaacggct gtcccgtatt tcgatcctga ggttaatcct tcaaacggga agttcatcag
    38281 gcccgggcgt tcatcgcccg tcgtgaacag ctgtacgcgg tgatactcag gttcgcctgc
    38341 ttcgttagtc agaatgcgaa atgagtgtgg atctacgact ttgcgtgttt ttgtttgacc
    38401 atcaacctga tactgcactt cctgactgtc aaacatcccc accggaacta cccaggtggc
    38461 aaggctggtt aaaatagcaa caaaaaagat aatcaccaac gtatcgggca ttgcccatct
    38521 tcttgttggt ttggattcag tgattgcgga catagcgcaa atattccctt gcacaaaaca
    38581 aagtggtaag tatgcaaagt gggatggcgc aattcattga tgcagcgcag ttaagcaaga
    38641 taatcagaaa ggattaatgc aaattaagag aataaaaaac cggaaatagt gattatttcc
    38701 ggttcagata tccgcagcgc aaagctgcgg atgatgacga gattactgct gctgtgcaga
    38761 ctgaatcgca gtcagcgcga tggtgtagac gatatcgtca accagtgcgc cacgggacag
    38821 gtcgttaacc ggcttgcgca taccctgcag catcggcccg atggagatca ggtcggcaga
    38881 acgctgtacc gctttgtagg tggtgttacc ggtgttcaga tccgggaaga tgaacacggt
    38941 agcgcgacct gcaaccggag agttcggcgc tttggatttc gcaacgtcag ccattaccgc
    39001 agcgtcgtac tgcagcggac cgtcgatcat caggtcagga cgtttttcct gcgccagacg
    39061 agttgcttcg cgaacttttt ctacgtcgct acctgcacca gaagtaccgg tggagtagga
    39121 gagcatagca acgcgcggtt cgataccgaa ggccgcagcg gaatcagcgg actgaatcgc
    39181 gatttctgcc agctgttcag cggtcggatc cgggttgatc gcacagtcac cgtaaacgta
    39241 aacctgttcc ggcagcagca tgaagaacac ggaagatacc agggagctgc ccggtgcagt
    39301 tttgatcagc tgcagcggcg gacggatggt gtttgcggta gtgtgaacag caccggaaac
    39361 cagaccatca acttcatcct gttccagcat cagcgtaccg agcaccacgt tgtcttccag
    39421 ctgttcgcgg gcaacggttt cggtcatgcc tttgttctta cgcagttcga ccagacgacc
    39481 aacatagctt tcgcgaacca cttctggatc aacgatttca atccctgcac ccagttctac
    39541 accctgagac gctgcaacac ggttgatctc tgccggatta cccagcagta cgcaagttgc
    39601 gataccacgt tcagcacaga tagcggctgc tttaacggta cgcggttcgt caccttccgg
    39661 cagtacgata cgtttgcccg ctttgcgcgc aagttcagtc agctgataac ggaacgcagg
    39721 cggagacaga cgacggctgc gctcagaagt ggcagtcaga gattcgatcc agtcagcgtt
    39781 gatgtagtta gcaacgtatt cctgaacttt ctcgatacgt tcgtgatcgt caaccggaac
    39841 ttccaggttg aagctctgca ggctcagaga ggtctgccag gtgttggtgt tcaccataaa
    39901 taccggcagg ccggtagcga aagcacgttc gcacagttta gaaatgcgcg cgtccatttc
    39961 gtaaccgcca gtcagcagca gggcaccgat ttctacgccg ttcatggctg ccaggcaagc
    40021 ggccaccagc acgtcaggac ggtctgcgga agtcaccagc agagaaccgg cacggaagtg
    40081 ctccagcatg tgcggaatgc tgcgtgcgca gaaagtgacg gatttaacgc ggcgagtatt
    40141 gatgtcgcct tcgttgatga tggtcgcatt caggtggcga gccatatcga tcgcacgagt
    40201 cgcgatcagg tcaaagctcc acggcacagc gccgagaacc ggcagcgggc tggattcttg
    40261 cagcttcgcc ggatcaacat tgtttacttt agctttggaa gagtcgtcga aaatctcgga
    40321 cagatccggg cgagtacgac cctgttcatc aaccggtgcg ttcagtttgt taacgataac
    40381 gccggtgatg ttggtgtttt tggcaccgcc gaagctgttg cgggtcagtt cgatacgctc
    40441 tttcagctgt tccggggtgt cagtgccctg agacataacg aagacgattt ccgcattcag
    40501 cgttttagcg atttcgtagt tcagagactg ggcaaactgg tgcttacgtg tcgggaccag
    40561 accttcaacc agaacgactt cagcgtcttt ggtgttagcg tggtagtttg cgacgatctc
    40621 ttccatcagc acatctttct gattgctgga aagcagacct tcaacgtagc tcattttcag
    40681 cggttcagcg gccgtcgtgg tggaagagtt cgcacgcacg atagtcgtag tctgatcggg
    40741 cgcatcgcca ccggtacgcg gctgagcgat aggtttgaaa acgctcagac gaacgccttt
    40801 gcgttccatt gcacggatca cgccaaggct gacgctggtc agaccgacgc tggttccggt
    40861 agggatcagc ataataatac gggacacggt ttatcctctt tcgttaccgc cgatttggcg
    40921 ggttacaaaa cagcaccgcc agctgagctg gcggtgtgaa atcaggcagt caggcggctc
    40981 gcgtcttgcg cgataaccag ttcttcgttg gttgggataa ccaccgcagg acgggtacct
    41041 tctttgttga tgaaaccaga tttgccgaaa cgtgcagcca ggttgcgttc atgatcaact
    41101 tcaaagccca gcacgcccag tttgcccaga gacagttcac gaaccattgc ggcattttca
    41161 ccgataccac cagtgaatac aacagcgtcc agacgaccat ccatcagcgc agtgtaggca
    41221 ccgatgtatt tcgccaggcg gtggcagtaa acgtccattg cgcgcttcgc gtcttctttc
    41281 gtcgcgtagt tgtcttcaac atagcggcag tcgctggtca cttcggtcag acccagcagg
    41341 ccagactctt tggtcagcag tttgttgatt gcgtcaacgc tcatgcccag ggtgtcgtgc
    41401 aggtggaaga tgatcgccgg atcgatatca ccagaacggg tacccatgac cagaccttcc
    41461 agcggggtca ggcccataga ggtgtcaacg catttaccgt tgcggatagc agaaacggaa
    41521 ccaccgttgc ccaggtggca ggtgatgatg ttcagttctt ctaccggttt gttcagcatt
    41581 tttgccgctt cctgggttac atagaagtgg ctggtgccgt gcgcgccgta acgacggatg
    41641 ccgtgctctt tgtacaggtt gtaaggcagg gcgtagaggt aagactcttc cggcatagtc
    41701 tggtggaacg cggtgtcaaa tacagcaacg tttttgtctt tcagctgtgg gaaagatttc
    41761 agagcttctt cgataccgat caggtgagcc gggttgtgca gcggtgcaaa agaagctgca
    41821 tctttgatac cctgaataac agactcatcg atcactacgg agctggtata cttttcgccg
    41881 ccgtgtacga tacggtgacc gatagcagtc agctgcgcag acagttctgg tttttgtgcc
    41941 agaatagtat taacgataaa gttgagcgct tcgctgtgag cggcgcctgc acctaaagcc
    42001 gcttcctgtt tattgccgtc cattttccat ttgatacgtg cttcgggcag gtggaaacat
    42061 tcggctaaac cagaaaggta ctcttcacca tttactgcat cgatgatggc aaatttcagt
    42121 gaagaactac cgcagttcag aaccagtact aacttactcg acatggaagt acctataatt
    42181 gatacgtggc taaaaaaacg tcagggagcc atagagcgta gcgcatgatg acaccgacat
    42241 ttatgattaa catcatgcac tgcaaatttt ttttgcatga tggaagaaat atcttgagtc
    42301 tatgccattt tgcgtaattt tcagccaatg gcataatgta tatgaatttg acgactcaat
    42361 gaatatgtac tacttaggcc ttcaggctgc taaaggatac ctgatagtgg gtatggaaga
    42421 caaaatgttt tgaacgttgt cccgctgagt tgtgaatttg cacaaatttt tgaatcttta
    42481 tatgtgaagt tgaggtgaag catgtcaacg ccggataatc gttctgttaa tttttttagc
    42541 ttgtttcgcc ggggacagca ttactcaaag acgtggccgc tggaaaaacg ccttgccccg
    42601 gtctttgtcg aaaatcgcgt tatcaagatg acgcgttatg cgatccgttt tatgccgccg
    42661 atcgccgtat ttactctctg ctggcagatt gccctgggcg gtcagcttgg gccggcagtt
    42721 gccactgccc tgttcgcctt aagtttaccc atgcagggat tgtggtggct gggcaagcgt
    42781 tctgtcacgc cattaccccc tgcaatcctt aactggtttt atgaagttcg cggtaaattg
    42841 caggagtctg gacaggtgtt ggcacccgtt gaaggcaagc ctgattacca ggcattagct
    42901 gacacgctta agcgcgcctt caaacaactg gataaaactt tccttgatga tttgtaattg
    42961 acccctgatt acgcatataa aagaaggcat actcagcctt cttttttttc accgtagtag
    43021 agtgatacag gagtcaacaa tggaaatgac caacgcgcaa cgtcttattt tgtctaatca
    43081 gtacaagatg atgactatgc tcgatccggc aaatgctgaa cgttaccgtc gcctgcaaac
    43141 aattattgag cgtggttacg gattacagat gcgtgaattg gatcgcgagt ttggcgagct
    43201 gaaagaagaa acctgccgca ctatcatcga cattatggag atgtatcatg cgttgcatgt
    43261 ttcctggtct aatttgcagg accagcaatc catcgatgaa cgtcgtgtca ccttcctcgg
    43321 ctttgacgcc gccactgaag cacgttacct cggttatgtc cgctttatgg ttaatgtgga
    43381 agggcgctat acccattttg acgccggaac tcacggtttt aacgcccaga cgccaatgtg
    43441 ggaaaaatat cagcgcatgc ttaatgtgtg gcatgcctgc ccgcgtcagt accatttgag
    43501 cgccaacgaa attaatcaaa ttatcaatgc ctgaggaggc ccgcgtgcgg tgcaaaggtt
    43561 ttctgtttga tcttgatgga acgctggtgg attccctgcc tgcggtagaa cgggcgtgga
    43621 gcaactgggc cagacgtcat gggttagcgc cggaagaggt gctggctttc attcacggta
    43681 aacaggcgat cacctctctg cgccatttta tggcgggcaa atccgaggct gatattgccg
    43741 ccgagtttac gcgtctggag cacatcgagg ccacggaaac cgaaggtatt accgcgcttc
    43801 cgggggcaat cgccttactc agtcatttga ataaagcagg tattccgtgg gccattgtga
    43861 cttctggctc catgccggta gcgcgagcgc gccataaaat agctgggctt cccgcaccag
    43921 aggtgtttgt aaccgctgag cgagtgaagc gcggaaaacc agaacctgat gcgtatctgt
    43981 taggcgcgca gctgctgggg cttgcgccgc aggagtgtgt ggtggtggaa gatgctcccg
    44041 ctggcgtgct ttctggcctg gcggcgggtt gtcatgtcat tgcggttaac gctccggcag
    44101 ataccccgcg cctgaatgag gtcgatttgg tcctccacag tctggagcaa attactgtga
    44161 ccaaacagcc aaatggcgat gttattattc agtgaaacac ctgatcatga tttagccccg
    44221 tctcgtcggg gcttttttat ggcagaatca agtcatcccc ctcaattaac aaggataagt
    44281 tgtgaacggt gaattgattt gggttctttc attactggcc gttgccatcg tcttgtttgc
    44341 gacgggcaga gtgcgtatgg atgcggtcgc tttgtttgtt attgtcgcgt ttgcattaag
    44401 cggaacgctg acagtcccag aagtattttc cggcttttct gatcctaacg ttgtcctgat
    44461 tgccgccttg tttattattg gcgatggttt ggtccgtacc ggtgttgcca ccgtaatggg
    44521 aacatggctg gtcaaagttg cgggcaatag tgaaatcaaa atgttggttt tgttgatgct
    44581 gaccgtcgcg gggcttggcg cgtttatgag ttcaaccggc gttgtcgcta tctttattcc
    44641 cgtggtgtta agcgttgcca tgcgtatgca aacgtcgccg tcacgtctga tgatgccgtt
    44701 aagttttgcc gggctgatta gcggcatgat gacgctggtg gcgacgccgc cgaacctggt
    44761 agtcaacagt gaattgctgc gtgaaggcta tcacggcttc agtttcttta gcgtaacacc
    44821 tattggcctg gtcgtgctgg tgctgggtat tttgtatatg ttagtgatgc gtttcatgct
    44881 gaaaggggat acccagaccc cgcagcgcga aggctggacg cgtcgaacct ttcgcgatct
    44941 tatccgtgaa tatcgactga ccgggcgtgc gcgacgtctg gctattcgcc ccggatcgcc
    45001 aatgattggt caacggctgg atgatctcaa attacgtgag cgttatggcg ctaacgtcat
    45061 cggtgttgaa cgctggcggc gttttcgtcg cgttatcgtg aacgttaatg gggtttctga
    45121 atttcgcgcg cgtgacgttt tgcttattga tatgtctgcg gctgatgtcg atctccggca
    45181 attttgtagt gagcaattgc tggagccgat ggtactgcgc ggcgagtatt tttctgacca
    45241 ggcccttgat gtgggcatgg cagagatttc attaattcct gagtcagaac tgattggtaa
    45301 atcggtgcgc gaaattggtt ttcgtacccg ctacggactg aatgtggtgg ggctaaagcg
    45361 caatggcgtg gcgctggaag gttcgctggc ggatgagcct ctgctgctgg gcgatatcat
    45421 cctggttgtg ggtaactgga aactgatcgg tatgctggcc aaacagggcc gcgacttcgt
    45481 agcgctgaac ttaccggaag aggtgagtga agcatcaccc gcgcacagcc aggcacccca
    45541 tgccattttc tgtctggtgc taatggtggc gttaatgctg acagatgaaa ttcctaatcc
    45601 tgttgccgct atcatcgcct gcctgctgat ggggaaattc cgctgtatag atgctgaaag
    45661 cgcctataaa tccattcact ggccgagcat tattttgatc gttgggatga tgccgtttgc
    45721 tgtggcatta cagaaaacgg gaggtgtcgc gctggcggtg aaagggctga tggacattgg
    45781 cggtggttac gggccacata tgatgctggg gtgtttgttt gtcttgtcgg cggttattgg
    45841 gctatttatc tctaataccg cgacggcggt gttgatggct ccgattgcgc tggctgctgc
    45901 caaaacgatg ggggtgtcgc cttatccatt cgcgatggtc gtggcgatgg cagcatccgc
    45961 cgcctttatg acaccggttt cttcacctgt taacacactg gttttaggtc cgggaaatta
    46021 cagcttcagt gactttgtga agttgggggt accgttcacc attatcgtga tggcggtttg
    46081 tgtggtgatg atcccgatgc tgtttccgtt ttgacaagag cctgatgtcg catccggcgc
    46141 ttattgcctg atgcgacgca gactccggct gcttacagcg gtgaatcctg gctaatctca
    46201 tcgagcgaaa gatggaagct gggaacaaat atttccatga agtagtccat ctcctggctg
    46261 cgacgcgctt caagcgtcgc ttccagtcgc gtttttgcca gcaagaattc attatttccg
    46321 gccgcgagtt cttccagaca tttcagatat gcacacagtg catctgcctg tttcaccagc
    46381 gatttttctt catcgctata tgcatgctcg tcaattaacg gcgcaaagat atcccgcagc
    46441 tcttccggaa ccatatcgac cagtttttgc tgagcgattt tttcaatagc cttgtactcc
    46501 tgagcgattt gcgaattgaa gtatttcacc ggagtaggga gatcgccggt gagcacttct
    46561 gaggcatcgt ggtacatcgc cagtaaagcg atacgttcgg cgttgacatt accgccaaat
    46621 tttcgatttt tgatagctgc cagcgcatgg gcgaccatcg ctacctgcaa actgtgttcg
    46681 gacacatttt ccgtccgcac gttgcgcatg agcggccagc ggttaatgag tttcaggcgg
    46741 gagagatggg caaaaaaatg gctctgtttc atagtgacct tacgtatgat gacatcatca
    46801 ggtcattgtg gcgggataac gctgccggat gcaatctccg gcagtgaaat taagattaca
    46861 gctgatgata accagaaagg aaacgcgcga acttgctcaa agacagctcg atatcatcga
    46921 cacgcggtag cgtgacaatg cggaagtgat ccggccacgg ccagttgaat gccgtccctt
    46981 gcaccaacag aactttttcc tgcaacagga aatccagcac cattttctga tcgtcgtgaa
    47041 tgttaaagcg tttggcgtcg attttcggga acatatacag cgcaccacga ggtttcacgc
    47101 aggaaacgcc cggaatatcg ttgatcagtt cccacgcgcg gttacgctgc tcataaagac
    47161 gaccgccagg ggtaataaat tcactgatgc tctgataacc acctagcgcg gtctgaatgg
    47221 cgtgttgcgc aggaacgtta gcacacaggc gcattgaagc cagcatttcc agaccttcga
    47281 tgtagccttt ggcgtgtttt ttcggcccgt tcaacaccat ccacccctga cggaagcctg
    47341 caacgcggta cgttttcgac agtccgttaa aggtaatggt cagcaggtca ggtgccagcg
    47401 gtgcaattga gtgatgctca gcgtcgtcgt agagaatttt gtcataaatt tcatcggcga
    47461 agataatgag attatgctga cgtgcaatct ccacaatctc cattaaaagc tctttggaat
    47521 ataccgcgcc ggttgggtta tttgggttga taataacgat cccacgcgta cgaggcgtaa
    47581 ttttagcgcg aatatcatcg aggtccggga accagtcaga ggattcatcg caaagataat
    47641 gcaccgcttt accgctggaa agcgaaaccg ccgcggtcca tagtgggtaa tctggtgcag
    47701 gaaccaacat ttcgtccccg ctgttcagca atgcctgcat tgcctgaacg ataagctccg
    47761 atacaccatt gccgatgtaa atatcttcca cggtaacatc acgcatgcca cgagcctggt
    47821 agtgctgcat gatggcttta cgcgcggagt aaagaccttt ggaatcgcaa tacccttgag
    47881 cggtaggcag gttgcgtatc acgtcaacga ggatttcatc tggcgcgtca aaaccgaacg
    47941 gggctgggtt gccgatgttc agtttcagta ccttgttacc ttcttcttcc aggcgttttg
    48001 cttctttcag caccggacca cggatgtcat aacagacatt ctctaatttg ctggattttt
    48061 caatggggga catgaatctt gacctttttt gctgttatcg ccactccctg ccgtggaagt
    48121 cagcttagaa caatgtactc ccccaggacg gtgttttgaa ggtctgcaga ataagatttt
    48181 gccagagggg aaggctcgat tgtgctgtta ataacttaat aatgacaaaa taatgag
//
LOCUS       DAPHKZ010000022        47229 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.022, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000022 DAPHKZ010000000
VERSION     DAPHKZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47229
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.022"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(51..416)
                     /locus_tag="RH288_001345"
     CDS             complement(51..416)
                     /locus_tag="RH288_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDV4030417.1"
                     /translation="MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKML
                     GWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFN
                     CQAGTPGENRFGPDPKLEP"
     gene            complement(710..1696)
                     /gene="yqjG"
                     /locus_tag="RH288_001346"
     CDS             complement(710..1696)
                     /gene="yqjG"
                     /locus_tag="RH288_001346"
                     /EC_number="1.8.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionyl-hydroquinone reductase YqjG"
                     /protein_id="HDV4030418.1"
                     /translation="MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTG
                     TGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSF
                     PGATGDTLYQNEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
                     DALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRD
                     IYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG"
     gene            complement(1766..2158)
                     /locus_tag="RH288_001347"
     CDS             complement(1766..2158)
                     /locus_tag="RH288_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDV4030419.1"
                     /translation="MKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVP
                     GFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKN
                     LTISGGFLLLAITGPGAYSIDRLLNKKW"
     gene            complement(2344..2643)
                     /locus_tag="RH288_001348"
     CDS             complement(2344..2643)
                     /locus_tag="RH288_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HDV4030420.1"
                     /translation="MSSKVERERRKAQLLSQIQQQRLDLSASRREWLETTGAYDRRWN
                     MLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG"
     gene            complement(2633..3037)
                     /locus_tag="RH288_001349"
     CDS             complement(2633..3037)
                     /locus_tag="RH288_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDV4030421.1"
                     /translation="MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEK
                     ANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIW
                     TLRKSRKSTLLRHTRHELANDRQLLEEESREQ"
     gene            complement(3040..3345)
                     /locus_tag="RH288_001350"
     CDS             complement(3040..3345)
                     /locus_tag="RH288_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HDV4030422.1"
                     /translation="MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAE
                     QALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR"
     gene            complement(3383..3751)
                     /locus_tag="RH288_001351"
     CDS             complement(3383..3751)
                     /locus_tag="RH288_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HDV4030423.1"
                     /translation="MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQ
                     NRIDGLNKALSEVRANCSDSQLRADHQKKIAKQKDEVAERQQDLAEAKQKGDADKIAK
                     RERKLAEAQEELKKLEARDY"
     gene            complement(3898..4281)
                     /gene="mzrA"
                     /locus_tag="RH288_001352"
     CDS             complement(3898..4281)
                     /gene="mzrA"
                     /locus_tag="RH288_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HDV4030424.1"
                     /translation="MQIPRMSLRQLAWSGAVLLLVGTLLLAWSAVRQQESTLAIRAVH
                     QGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQSAAAKAVLDRTLPHGYI
                     IAQQDNNSQAMQWLTRLRDNSHRFG"
     gene            complement(4285..4947)
                     /locus_tag="RH288_001353"
     CDS             complement(4285..4947)
                     /locus_tag="RH288_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV4030425.1"
                     /translation="MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLP
                     AAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
                     GLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGN
                     RG"
     gene            complement(5292..6068)
                     /gene="exuR"
                     /locus_tag="RH288_001354"
     CDS             complement(5292..6068)
                     /gene="exuR"
                     /locus_tag="RH288_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ExuR"
                     /protein_id="HDV4030426.1"
                     /translation="MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNV
                     SRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQQAADNNMEFANYGPFELLQARQ
                     LIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
                     AIVEKMWTQRSHNPYWKKLHEHIDSRTVDNWCDDHDQILKALIRKDPHAAKLAMWQHL
                     ENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTATSGSK"
     gene            complement(6198..7496)
                     /gene="exuT"
                     /locus_tag="RH288_001355"
     CDS             complement(6198..7496)
                     /gene="exuT"
                     /locus_tag="RH288_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexuronate transporter ExuT"
                     /protein_id="HDV4030427.1"
                     /translation="MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNIST
                     QQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLA
                     VARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
                     HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKM
                     SVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFA
                     DLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCI
                     GGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSP
                     LFAVLAVFDLLGALVIWTVLQNKPAIEVAQETHNDPAPQH"
     gene            7979..9391
                     /gene="uxaC"
                     /locus_tag="RH288_001356"
     CDS             7979..9391
                     /gene="uxaC"
                     /locus_tag="RH288_001356"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDV4030428.1"
                     /translation="MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAED
                     YRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYH
                     WTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
                     IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADL
                     QTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFK
                     TAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLL
                     SKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMER
                     QMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLG
                     EMVKNICFNNARDYFAIELN"
     gene            9406..10893
                     /gene="uxaA"
                     /locus_tag="RH288_001357"
     CDS             9406..10893
                     /gene="uxaA"
                     /locus_tag="RH288_001357"
                     /EC_number="4.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDV4030429.1"
                     /translation="MQYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKF
                     ALTDIAKGANVIKYGLPIGYALADIAAGVHVHAHNTRTNLSDLDQYRYQPDFQDLPAQ
                     AADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
                     SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPER
                     VHFMICQQQDDEIEAGIEHLHQLYNVMRNDKREPGKLSELKFGLECGGSDGLSGITAN
                     PMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIA
                     HDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAP
                     GNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQL
                     IHGKAMPQLLEEFIDTIVEFANGKQTCNERNDFRELAIFKSGVTL"
     gene            10976..11527
                     /locus_tag="RH288_001358"
     CDS             10976..11527
                     /locus_tag="RH288_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HDV4030430.1"
                     /translation="MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVH
                     FFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIG
                     TIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
                     RMQKRGIDPFKVEKTPSAVDERG"
     gene            complement(11532..12776)
                     /gene="sstT"
                     /locus_tag="RH288_001359"
     CDS             complement(11532..12776)
                     /gene="sstT"
                     /locus_tag="RH288_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HDV4030431.1"
                     /translation="MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVG
                     LLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVF
                     SFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQL
                     LVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDDRLANSALRN"
     gene            complement(13175..14140)
                     /gene="alx"
                     /locus_tag="RH288_001360"
     CDS             complement(13175..14140)
                     /gene="alx"
                     /locus_tag="RH288_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family membrane protein Alx"
                     /protein_id="HDV4030432.1"
                     /translation="MNTVGTPLLWGGFAVVVAIMLAIDLLLQGRRGAHAMTMKQAAAW
                     SLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
                     AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRGG"
     gene            complement(14423..15409)
                     /locus_tag="RH288_001361"
     CDS             complement(14423..15409)
                     /locus_tag="RH288_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDV4030433.1"
                     /translation="MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFAN
                     DFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQTQLFLSHKINVICEKPLASNLAE
                     VDAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
                     DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHI
                     NTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVIFPADSVKL"
     gene            complement(15488..16180)
                     /locus_tag="RH288_001362"
     CDS             complement(15488..16180)
                     /locus_tag="RH288_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HDV4030434.1"
                     /translation="MLRAFARLLLRICFSRRTLKIACLLLLVAGATILIADRVMVNAS
                     KQLTWSDVNAVPARNVGLLLGARPGNRYFTRRIDTAAALYHAGKVKWLLVSGDNGRKN
                     YDEASGMQQALIAKGVPAKVIFCDYAGFSTLDSVVRAKKVFGENHITIISQEFHNQRA
                     IWLAKQYGIDAIGFNAPDLNMKHGFYTQLREKLARVSAVIDAKILHRQPKYLGPSVMI
                     GPFSEHGCPAQK"
     gene            complement(16257..16760)
                     /locus_tag="RH288_001363"
     CDS             complement(16257..16760)
                     /locus_tag="RH288_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417556.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDV4030435.1"
                     /translation="MSNLTYLQGYPEQLLSQVRTLINEQRLGDVLAKRYPGTHDYATD
                     KALWQYTQDLKNQFLRNAPPINKVMYDNKIHVLKNALGLHTAVSRVQGGKLKAKVEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
                     SLGQNKI"
     gene            16845..17981
                     /gene="rlmG"
                     /locus_tag="RH288_001364"
     CDS             16845..17981
                     /gene="rlmG"
                     /locus_tag="RH288_001364"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417555.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HDV4030436.1"
                     /translation="MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEI
                     RGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTAD
                     YPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFNEPQLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNM
                     PEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR"
     gene            18265..18579
                     /gene="higB"
                     /locus_tag="RH288_001365"
     CDS             18265..18579
                     /gene="higB"
                     /locus_tag="RH288_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin HigB"
                     /protein_id="HDV4030437.1"
                     /translation="MHLITQKALKDAAEKYPQHKTELVALGNTIAKGYFKKPESLKAV
                     FPSLDNFKYLDKHYVFNVGGNELRVVAMVFFESQKCYIREVMTHKEYDFFTAVHRTKG
                     KK"
     gene            18576..18992
                     /gene="higA"
                     /locus_tag="RH288_001366"
     CDS             18576..18992
                     /gene="higA"
                     /locus_tag="RH288_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HigA"
                     /protein_id="HDV4030438.1"
                     /translation="MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLND
                     PENPLLDLVCAKITAWEESAPEFAEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIG
                     SKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID"
     gene            complement(19037..21055)
                     /gene="fadH"
                     /locus_tag="RH288_001367"
     CDS             complement(19037..21055)
                     /gene="fadH"
                     /locus_tag="RH288_001367"
                     /EC_number="1.3.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="HDV4030439.1"
                     /translation="MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFY
                     AERARHGVALIVSGGIAPDLTGVGMEGGAMLNDASQIPHHRTITEAVHQEGGKIALQI
                     LHTGRYSYQPHLVAPSALQAPINRFVPHELSHEEILQLIDNFARCAQLAREAGYDGVE
                     VMGSEGYLINEFLTLRTNQHSDQWGGDYRNRMRFAVEVVRAVRERVGNDFIIIYRLSM
                     LDLVEDGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKL
                     KGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINT
                     CIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAIN
                     AAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMIEVTGVTLKLNHTVT
                     ADQLQAFDETILASGIVPRTPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGIGF
                     DTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS
                     KPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVIC
                     AGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI"
     gene            complement(21481..23832)
                     /gene="ygjK"
                     /locus_tag="RH288_001368"
     CDS             complement(21481..23832)
                     /gene="ygjK"
                     /locus_tag="RH288_001368"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDV4030440.1"
                     /translation="MKIKTILTPVTCALLISFSAHAANADNYKNVINRTGAPQYMKDY
                     DYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVALLTEEYINFMASNFDRLTVWQD
                     GKKVDFTLEAYSIPGALVQKLTAKDVQVEMTLRFATPRTSLLETKITSNKPLDLVWDG
                     ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEY
                     QVHKSLPVQTEINGNRFTSKAHINGSTTLYTTYSHLLTAQEVSKEQMQIRDILARPAF
                     YLTASQQRREEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSPGGAVKFNTVTPSVT
                     GRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDSVRPQDVGFVPDL
                     IAWNLSPERGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKTWVAEMYPKLVAYHDWWL
                     RNRDHNGNGVPEYGATRDKAHNTESGEMLFTVKKGDKEETQSGLNNYARVVEKGQYDS
                     LEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVANGGKRSDWTVKFAENRSQDGTLLG
                     YSLLQESVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLADYINTCMFDPTTQ
                     FYYDVRIEDKPLANGCAGKPIVERGKGPEGWSPLFNGAATQANADAVVKVMLDPKEFN
                     TFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGMERYGYRDDALKLADTFFRHAK
                     GLTADGPIQENYNPLTGAQQGAPNFSWSAAHLYMLYNDFFRKQ"
     gene            complement(23849..24919)
                     /gene="ygjJ"
                     /locus_tag="RH288_001369"
     CDS             complement(23849..24919)
                     /gene="ygjJ"
                     /locus_tag="RH288_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgjJ"
                     /protein_id="HDV4030441.1"
                     /translation="MKLITAPCRALLALPFCYAFSAAGEEARPAEHDDTKTPAITSTS
                     SPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGLEMKYGSWFGLIYGEGWTVQADH
                     DGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
                     VIPNTRDIMTALKVQNLSGNFRYSVTATPAGHHDESKAWLHFGKYDRYDDKYTYPAMM
                     NGYIQYDLAEGITWMNGLEITDGTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSES
                     GMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWYEYGGGRFATAFDSR
                     FYMKNASHDPSDQIFLMQYFYW"
     gene            complement(25053..26486)
                     /locus_tag="RH288_001370"
     CDS             complement(25053..26486)
                     /locus_tag="RH288_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV4030442.1"
                     /translation="MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFF
                     LATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSLGGRWAFITAYTYWFVNLFFFTS
                     LLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
                     LLLTLSYILLAGTALVGGVQPADAITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVY
                     VNDVKGGSKSFVKVIILAGIFIGVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAY
                     FGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIFGKKTVELNENGVPA
                     RAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLD
                     HLPRDFRMGSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFA
                     WWKYSKYIKGLTAEERHIEATPASNVD"
     gene            complement(26549..26998)
                     /locus_tag="RH288_001371"
     CDS             complement(26549..26998)
                     /locus_tag="RH288_001371"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit beta"
                     /protein_id="HDV4030443.1"
                     /translation="MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPGVAHSIGDS
                     LTYRVETDSATDALFTGHRRYFEVHYYLQGQQKIEYAPKETLQVVEYYRDETDREYLK
                     GCGETVEVHEGQIVICDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK"
     gene            complement(26995..30087)
                     /gene="ebgA"
                     /locus_tag="RH288_001372"
     CDS             complement(26995..30087)
                     /gene="ebgA"
                     /locus_tag="RH288_001372"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit alpha"
                     /protein_id="HDV4030444.1"
                     /translation="MNRWENIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLPL
                     SGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVP
                     FVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
                     DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLVGKHLTHINDFTVRT
                     DFDEAYCDATLSCEVVLENLAASPVVTTLEYTLFDGERVVHSSAIDHLAIEKLTSASF
                     AFTVEQPQQWSAESPYLYHLVMTLKDANGNVLEVVPQRVGFRDIKVRDGLFWINNRYV
                     MLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGL
                     FVMAETDVESHGFANVGDISRITDDPQWEKVYVERIVRHIHAQKNHPSIIIWSLGNES
                     GYGCNIRAMYHAAKALDDTRLVHYEEDRDAEVVDIISTMYTRVPLMNEFGEYPHPKPR
                     IICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDHGNVWYKFGGD
                     YGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHARDLTRGELKVENKLWFTT
                     LDDYTLHAEVRAEGETLATQQIKLRDVAPNSEAPLQITLPQLDAREAFLNITVTKDSR
                     TRYSEAGHPIATYQFPLKENTAQPVPFAPNNARPLTLEDDRLSCTVRGYNFAITFSKM
                     SGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRDFAVEQ
                     SDGEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFT
                     MGINGEYDQVAYYGRGPGENYADSQQANIIDIWRSTVDAMFENYPFPQNNGNRQHVRW
                     TALTNRHGNGLLVVPQRPINFSAWHYTQENIHAAQHCNELQRSDDITLNLDHQLLGLG
                     SNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSLASYEFGAGFFSTNLHSENKQ
                     "
     gene            complement(30271..31254)
                     /gene="ebgR"
                     /locus_tag="RH288_001373"
     CDS             complement(30271..31254)
                     /gene="ebgR"
                     /locus_tag="RH288_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator EbgR"
                     /protein_id="HDV4030445.1"
                     /translation="MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEK
                     LEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDPYYLAIRHGIETQCEKLGIELTN
                     CYEHSGLPDIKNVTGILIVGKPTPALRAAASALTDNICFIDFHEPGSGYDAVDIDLAR
                     ISKEIIDFYINQGVNRIGFIGGEDEPGKADIREVAFAEYGRLKQVVREEDIWRGGFSS
                     SSGYELAKQMLAREDYPKALFVASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTAR
                     FTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLVFVPSKLKLRGTTR"
     gene            31473..31805
                     /locus_tag="RH288_001374"
     CDS             31473..31805
                     /locus_tag="RH288_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDV4030446.1"
                     /translation="METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGQKTLQ
                     TVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERM
                     MPAGVRVV"
     gene            complement(31847..33226)
                     /gene="ygjG"
                     /locus_tag="RH288_001375"
     CDS             complement(31847..33226)
                     /gene="ygjG"
                     /locus_tag="RH288_001375"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417544.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HDV4030447.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAM
                     RTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMA
                     IEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALA
                     AMRVSVEEA"
     gene            33644..35164
                     /gene="aer"
                     /locus_tag="RH288_001376"
     CDS             33644..35164
                     /gene="aer"
                     /locus_tag="RH288_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerotaxis sensor receptor Aer"
                     /protein_id="HDV4030448.1"
                     /translation="MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYT
                     LQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPM
                     VREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
                     LRWRARGVMTLMFILLAAMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVAHQ
                     ALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAK
                     GTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAM
                     TTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQIS
                     HSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH"
     gene            complement(35318..35941)
                     /gene="nfeR"
                     /locus_tag="RH288_001377"
                     /gene_synonym="yqjI"
     CDS             complement(35318..35941)
                     /gene="nfeR"
                     /locus_tag="RH288_001377"
                     /gene_synonym="yqjI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NfeR"
                     /protein_id="HDV4030449.1"
                     /translation="MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCG
                     GRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYP
                     TLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQ
                     NPQMKRALDNFKAVLDLRVNQSDISDAQIKKIIAVIDRAAFDITQLD"
     gene            36229..36993
                     /gene="nfeF"
                     /locus_tag="RH288_001378"
     CDS             36229..36993
                     /gene="nfeF"
                     /locus_tag="RH288_001378"
                     /EC_number="1.16.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent ferric chelate reductase"
                     /protein_id="HDV4030450.1"
                     /translation="MNNTPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDG
                     FTSRGFDDHSKLFFPQPDAHFVPPTVTEEGIVWPEGPRPPSRDYTPLYDELRHELAID
                     FFIHDGGVASGWAMQAQPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLET
                     LSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYF
                     IWITGEGKVVKNLSRRFEAEQYDPQRVRAAAYWHAK"
     gene            complement(37047..37122)
                     /locus_tag="RH288_001379"
     tRNA            complement(37047..37122)
                     /locus_tag="RH288_001379"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37087..37089),aa:Ile,seq:cat)
     gene            37247..37753
                     /gene="mug"
                     /locus_tag="RH288_001380"
     CDS             37247..37753
                     /gene="mug"
                     /locus_tag="RH288_001380"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HDV4030451.1"
                     /translation="MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQA
                     GFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQ
                     ALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
                     QALVVRGR"
     gene            complement(37832..39673)
                     /gene="rpoD"
                     /locus_tag="RH288_001381"
     CDS             complement(37832..39673)
                     /gene="rpoD"
                     /locus_tag="RH288_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDV4030452.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYM
                     REMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
                     LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAR
                     EKFAELRAQYVVTRDTIKAKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM
                     MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
                     EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISME
                     TPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGID
                     MNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(39868..41613)
                     /gene="dnaG"
                     /locus_tag="RH288_001382"
     CDS             complement(39868..41613)
                     /gene="dnaG"
                     /locus_tag="RH288_001382"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDV4030453.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAG
                     SGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGF
                     APPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQY
                     GINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQ
                     LRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLS
                     TLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTT
                     MRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYR
                     GTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNE
                     ERLELWTLNQELAKK"
     gene            complement(41724..41939)
                     /gene="rpsU"
                     /locus_tag="RH288_001383"
     CDS             complement(41724..41939)
                     /gene="rpsU"
                     /locus_tag="RH288_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDV4030454.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            42177..43190
                     /gene="tsaD"
                     /locus_tag="RH288_001384"
     CDS             42177..43190
                     /gene="tsaD"
                     /locus_tag="RH288_001384"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDV4030455.1"
                     /translation="MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     DVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLR
                     AKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAEL
                     PAA"
     gene            complement(43233..44696)
                     /gene="ttdT"
                     /locus_tag="RH288_001385"
     CDS             complement(43233..44696)
                     /gene="ttdT"
                     /locus_tag="RH288_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-tartrate/succinate antiporter"
                     /protein_id="HDV4030456.1"
                     /translation="MKPSTEWWRYLAPLAVIAIIALLPVPAGLENHTWLYFAVFTGVI
                     VGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSV
                     IWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
                     RGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLL
                     IGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETEL
                     QAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSN
                     KAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTMVMVALIVVFYLLRY
                     FFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYG
                     SGYLPTADYWRLGAIFGLIFLVLLVITGLLWMPVVLL"
     gene            complement(44744..45349)
                     /gene="ttdB"
                     /locus_tag="RH288_001386"
     CDS             complement(44744..45349)
                     /gene="ttdB"
                     /locus_tag="RH288_001386"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HDV4030457.1"
                     /translation="MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELK
                     RPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGK
                     GGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
                     GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK"
     gene            complement(45346..46257)
                     /gene="ttdA"
                     /locus_tag="RH288_001387"
     CDS             complement(45346..46257)
                     /gene="ttdA"
                     /locus_tag="RH288_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HDV4030458.1"
                     /translation="MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAE
                     TSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVE
                     EATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPG
                     RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPI
                     GSRHPNPKAAELELRLEEGLNRLGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTG
                     CWAHRRGTLLVHADLTFENLSHTRSAL"
     gene            46464..47039
                     /gene="ttdR"
                     /locus_tag="RH288_001388"
                     /gene_synonym="dan"
                     /pseudo
     CDS             46464..47039
                     /gene="ttdR"
                     /locus_tag="RH288_001388"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159753.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TtdR"
     gene            47095..>47229
                     /locus_tag="RH288_001389"
     CDS             47095..>47229
                     /locus_tag="RH288_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HDV4030459.1"
                     /translation="MASVSISCPSCSATDGVMRNGKSTAGHQRYLCSHCRKTWQLQFT
                     Y"
BASE COUNT        11318 a        12300 c        12387 g        11224 t
ORIGIN      
        1 acataatgat aaaagccgga tgagtcagac atccggcgag cagatttgtt ttaaggttcc
       61 agttttggat ctggtccaaa gcggttttcg cctggcgtac ccgcctggca gttaaagacg
      121 atgataataa gccagccgat aaacgggatt aagaatagca gtgcccacca cgccgagcgg
      181 tcggtgtcgt gcaggcggcg gaactgaacc gcccaccacg gtaaaaacac cagaataccg
      241 tagattgtcg tcaggatgcc ttcgccacca gcgcgttgcc agcctaacat tttatccagc
      301 agccccagca cgaacgtaaa gatgatgttg accagaataa acatccagta ctctttgcgc
      361 cgcgcacgac cccggaaacc gacataattt tttagtactt tcagatacca gtccattttt
      421 gcctcaattt tgctcaatca cttgttttta aagcagcaaa ttaagaatag acgtgaatga
      481 aatggcagta aatattcgtt caaggaatta ataaagtgcc gtgaaggcgc gctaagactg
      541 atgacaagcg caaaatcgcc agatgcgcta cgcttatctg gtctgcgcgg gttatgcaat
      601 ctattgaatg tacaatgttt tgtatgtcag ataaggcgtt catgccacat ccgacatgaa
      661 caacatgcac ttagctaatt atcagaggca cctcgtaagg tgcctttttt taaccgaagc
      721 gaacatctcg tccatgcggt tcatcgagat cctgccacgg accaattgaa ataatccccg
      781 tagggttgat ggtcttatgg ctgcggaagt aatgattacg gatatgatcg aaattgactg
      841 tttcggcgat ccccggcatc tggtagatat cgcgcagaaa accgtacaga ttcaggtaat
      901 cgctgatgcg gtgcttatca cacttgaagt gggtcacata caccggatca aaacgcacca
      961 gcgtagtcca caggcgaata tcggcttcgg ttagctggtt gccggtcagg taacgatgct
     1021 ggcctaaaat ctgctccagt cgtgccagcg attcaaacac tttcgccacc gcctcgtcgt
     1081 aagcttcctg gctggtggca aaaccagctt tatacacgcc gttgttaacg gtgtcataaa
     1141 tccagccgtt aagttcgtca atttttgttt gcagggctgg agggtagtaa tcacccgctt
     1201 tcgcgcccag cgcatcaaac gcggtattga acatgcggat gatttctgct gattcgttgc
     1261 tgacgatggt gtggttcttt ttgtcccaca gcacgggaac agtaactcgt ccgctgtagt
     1321 gtggatcggc gtggagataa agctggtaca gaaattcatt ttgatagagc gtgtctccgg
     1381 ttgctcccgg aaaactgtca tcaaaggtcc aaccgttttc cagcatcagc gggttcacta
     1441 cggaaacgga aataaacggt tccagtcctt tgagtttgcg catgatcagc gtgcggtgcg
     1501 cccacgggca ggcgagtgaa acatagagat gataacgatc tttctctgcg ataaaaccgc
     1561 ctgtgccagt ggggccagga gcgccatcgg cagtgagcca gttacgaaat gcggaagctg
     1621 aacgttgaaa tttaccgccg gtagatttgg tatcgtacca ggtgtcatgc cagacgccgt
     1681 caatcagttg acccattttt ctctcctcca atagcaaaaa cgaggagctt cctcctcgtt
     1741 ttttatcgtt aagtatagcg cgtgcttacc actttttatt cagcaggcgg tcgatgctat
     1801 acgcgcccgg accggtaatt gccagcagca ggaatccgcc agaaattgtc aggtttttca
     1861 tgaacatcag cgagttgacg ccttcagcaa agttgctgtg aaataaaaat gccgtcagca
     1921 gcgtaaagcc cgcagtaaac agggctgtgg tgcgagtcag gaaaccgaac aggattgcca
     1981 gaccaccacc aaactcaagc agaatcacca gcggcagcat aaaacccggg acgcccattg
     2041 cttccatata ttgttgggta cccgcgtagc cagtaatttt tccccagcca gcggtaataa
     2101 acagaatcgg cattaaaatg cgcgctacca gtacaccaac atcttctaat tttttcatca
     2161 tactctccac tgcgccactc aggctgctga ttgttttttt gtgcaatggc gcggtattag
     2221 cgtcgttgct gtcgatggag agaatcataa acgtggtgaa tgatgattgt tagcaaggaa
     2281 aactgtcaaa aatcttcaaa aaatttgagg gataaggccg gaatggctcc ggccagaggg
     2341 aagttaaccg cgaagctgtt gctgcttgag ggtcgtttta accagacgcc aggcgctcca
     2401 tacgccaaaa ccgcgtctgg cccagcggac cagcatatta ggatggcgaa tcgtccagat
     2461 cgccatcacg ctactgccaa ccagcgccca ggagcgcaga cttagcagca tattccagcg
     2521 acgatcgtaa gcgcctgttg tctccagcca ttcacgacga ctggcggaaa gatccagccg
     2581 ttgttgctgg atctggctaa gcagttgcgc cttacgtcgt tcacgttcga ctttactgct
     2641 cacgggactc ctcctcgagc agctgccgat cgtttgctaa ctcatggcgt gtatggcgca
     2701 gcaacgtaga cttacgcgat ttacgtagcg tccagatacc gccaatcagt gccagtagca
     2761 gcaacaccac ggtggtggca atcatcgcat tcaggcgata ttgcgggtca accgcccaaa
     2821 taattagcac catcaggctc ataagaccaa atgcagcgaa aagcatcgtc aggcccagca
     2881 tcagtaaaag ttgaaagaga ttcgcttttt cctcttccag ctccaccacc gccagccgca
     2941 gacgtgtctc taccatttca accatgatag aaacaattcg ctgcccgatg cccagaacgc
     3001 ttttaccggg cccttgtgcg tgatgagtgt ccgccataat taacgacgcg acagcagaac
     3061 gccgagcact acaccgattg cagcgccaat gcccacgccc gtccacggat tttcgcgcac
     3121 atactcatcg gcacgcgccg ccgcgacacg ggtttgtttg gcaatggcat caccggtttc
     3181 acccaggcga taacggctct gtttcagtgc ctgctccgct ttgctacgaa tcttactcaa
     3241 ctcttctttc gacttctcgc cagatgagct aagcacctct tccagcgtat cggaaaggga
     3301 tttcaactca gcacgcagat gttccgtagt gtgttctttc gacatagttt tctccaggtg
     3361 agtaagtagt gactattgtg agttagtagt cgcgcgcttc cagctttttc agctcttcct
     3421 gcgcttctgc cagtttccgt tcgcgtttgg caatcttatc ggcatcgcct ttttgcttcg
     3481 cctcggctaa atcttgctgg cgttccgcca cctcatcttt ctgctttgcg attttcttct
     3541 gatgatcggc acgcagctgg ctatctgaac agttggcccg gacttcactc agggctttat
     3601 tcagaccgtc aatacgattc tggttttggt gtttttcggc atagctgatc tccttaagga
     3661 tattttgctc cttttcctga cacagggtag tggcataact accggcacta agagcaaaga
     3721 gagaaacagc taaagcgatg cggtatttca ttcttgaacc ttccattgtg attcggacct
     3781 attacaaagg aacgattgtc cagacaacga agcggtagtg ttaaccaccg cctcattaat
     3841 catagacagt tacggtgaaa tcaccaaagt gagtgatatg tttcggataa caggaagtta
     3901 tccgaagcga tgagagttat cccgtaaccg ggtcagccac tgcatagcct gactgttatt
     3961 gtcctgctgc gcaatgatgt agccatgggg caatgttctg tcgaggaccg cttttgcggc
     4021 ggcgctctgg tcgctggagt caaatgtaat taacagagtg tcgtttttgg gggtgatact
     4081 tttgaaagga atgccatgag cgtcaaggtg atgccagatt gaaaaaccgt ctggcatcgt
     4141 tgtgccttga tgaacggcac gaatcgccag cgtagactct tgctggcgaa ccgcggacca
     4201 ggccagcaac agcgtgccga ccagaagtaa aacagcgccg gaccaggcta gctggcgaag
     4261 cgacatgcga ggtatttgca tcccttaccc ccgatttcca tatttctttt tccataacac
     4321 gaccagagaa cctgccaggc caaacaccag cagcaccacc gggagcaaca tcaggcatga
     4381 catcagctgg tcctcgtact ttaaaaatac cggcgttttg ccgagcatgt aacccagagt
     4441 tgtcaggatc aatacccaca gcagaccgct catccagttg aaaaactgaa agcgcgcgtt
     4501 attcagccct gataacccgg caatcgtcgg cagcagtgtt ctgacaaacg caataaagcg
     4561 accaattaac agcgccgata aaccgtgttt atgaaaaaga tggtgtgcgc gttgatgata
     4621 atgcgcgggt aaatgagata gccagttttg tacggtgcgg gtattgccca gccatcgccc
     4681 ctgaatatag ctgacccagc agccgaggct ggcggcaacg gtcagcagca gaatcgtttg
     4741 cggatagccc atcgcgcctt tcgcaatcaa cacgccgacc aataccagta aactgtcgcc
     4801 cggtaaaaag gccgccggaa gcaagccgtt ttcaaggaac aaaattacaa acaagacaaa
     4861 atacaacatg ccaatcatcg atggattggc cagggtttca aaatcctgcg cccacagggc
     4921 ttgcagcaat tgggtcaaaa gttccattca ttattcctgg tgaatcggtt aacgccacgc
     4981 tggttttaaa agatgcacta ccgcaatgtt attgctgttt tggtatgttc tgcgggtttg
     5041 atacatcaac acagcctgaa ctattccctg ttaaatcgtg agataagaaa gcattcaaaa
     5101 acataaattc aaattgaatc taattgtaac aaaggtcaac gttgttcgtt atcaaaatta
     5161 catgtccgtg gagtctgatt ttgctgaatg caggggaggg tggcgagagg atttacacag
     5221 gctgacactt tatacttttc gcttaccgac gagacaaaca ggcgcattgc agcgcctgtc
     5281 ggacaggaat ttcatttact gccgctggtg gctgtatcga gatgcaccac cgggttttcg
     5341 gcgaatagat agcggtcggc attgaactcg aagtcgtcgc tggtttcgtt aaataacatg
     5401 atcttggtgt tttccagatg ctgccacatt gccagcttag cagcatgagg atctttgcga
     5461 atcagcgcct tgaggatttg atcgtggtca tcacaccagt tatcgacggt acgggaatca
     5521 atgtgttcgt gcagtttttt ccagtacggg ttatgactac gctgggtcca cattttttcc
     5581 acgatagccg ccagggcgga gttctgcgtc gccagagcga cctgaatgtg gaactgcaaa
     5641 tcccactcgg aatcacggaa gcattgttcg ccgcgcgcct gttcctgaat ggccatcagt
     5701 ttcatgatgt cctgtttcgt tacctgagtt gccgcgaatt cggcaatatt actttcgatg
     5761 agctggcgag cctgaagcaa ctcaaacgga ccgtaattgg cgaattccat attattgtca
     5821 gccgcctgct gatggcgcgg ctggttggaa accacatgaa tacctgaacc tttacgcact
     5881 tcgacatagc cttcaacttc cagcatgatg atggcttcac gaactaccgt acggctgacg
     5941 ttcttttcat cggcaataaa gcgttctgca ggcagtttat cacccaccag atagacgccc
     6001 tgttcgatgc gctctttcag gtcagcggca agttgttgat acaaacggcg tggttcagtg
     6061 atttccatat gcgctccagg catgatacgg cagactatat ttgttatacc acttttgcga
     6121 gtttagctct actcgcagtg atgaaaaagc cgcctgagaa ggcggctttg aagggaaact
     6181 aaaacttaca cgaaacgtta atgttgcggt gcgggatcgt tatgtgtttc ctgcgccacc
     6241 tcaatcgccg gtttgttctg caacacggtc cagataacca gcgcacctaa caggtcgaac
     6301 actgccagaa ctgcgaacag cgggctgaag ccgatggtgt cagccagtgc accgacaacc
     6361 agcgcaaaca gcgtacttgc cagccatgcg gacatcccgg ttaaaccgtt tgccgttgcc
     6421 acttcgttac gaccaaacac atcggaagag agcgtaatca gcgcgccaga cagtgcctgg
     6481 tgggcaaaac caccgataca cagcagcata attgcgacat acgggttggt gaacaggccg
     6541 atcatacccg ggccaatcat cagcactgca cccagcgtta cgaccatctt acgggaaacg
     6601 atcaggttca caccaaacca acgctggaac agcggcggca ggtaaccacc gaggatacaa
     6661 ccgaggtcag caaacagcat cggcatccag gcgaacatcg cgatctcttt caggttaaag
     6721 ccgtaaactt taaacatgaa cagcgggatc cacgcgttaa aagtacccca ggccggttct
     6781 gccaggaaac gcggcagcgc gataccccag aactgacggt tacgcaggat ctgaccaacg
     6841 gacattttct tcgccgtgct cacctggtgc tgggcttcct gaccattaat aatatagtcg
     6901 cgttcttcat cggtcagatg cttctggtcg cgcggatgtt tatagaaaat cagccatgcc
     6961 atcgcccaga taaagctcaa tgcaccggag atgataaatg ccatctgcca gctgtgcatt
     7021 acgattgccc ataccaccag cggcggcgca atcatcgcac caatcgaaga acctacgtta
     7081 aagtagccta ctgcgatgga acgctctttc gccgggaacc attcggagct ggctttcaga
     7141 cccgccggga tcatcgctgc ttccgcggca ccgaccgcac cacgagcaac agccaggcca
     7201 ccccagctac ctgccagcgc ggttgcacca cagaacacgg cccacagcac agcaaacatt
     7261 gcataaccga ttttcgtacc cagcacatcc agtacataac ctgctaccgg ttgcatgacc
     7321 gtataagcag cagaataggc tgcgatgata taggaatact gttgggtgga gatgtttaac
     7381 tcttccatca gagttggcgc agctgccgcc acagtgttac gcgtcaggta accaagcacg
     7441 gtgccgagcg tcaccagtgc gatcatatac caacgtaacc ctttaatttt acgcatgtaa
     7501 aacctcatcg ttttgttata tccgcaggaa gcgcggccat catcccgcca gaggctgaag
     7561 atgttagtta cgaccgggta accgaaaaaa aaccggcacg ccccgaacgt tgccatgaaa
     7621 gtttcgtgct aattcggctt ccgtaccggt taacccgatt catctaacaa atgaatgaat
     7681 cggcaatttg cattccgtcg acttatgatt tgcgacggca gaaagataac ttgtcataca
     7741 actttaaaag gtgagagcca tcacaaatgt gggaatattt gtagggacat tacctgacga
     7801 cagcaaggcc agtactggcg cggcctgcag cgagatttac cactttgaga gtaatttttt
     7861 taactacgtt tattgatcta actcacgaaa atatcttcgg actctggaaa ttggtgtgat
     7921 aactttgtca gcatcgcacc ataagcaagc tagctcactc gttgagagga agacgaaaat
     7981 gactccgttt atgactgaag atttcctgtt agataccgaa tttgcccgcc gtctgtatca
     8041 cgactacgca aaagaccagc cgattttcga ttaccattgc catttgccgc cgcagcagat
     8101 tgcggaagac tatcgtttta aaaacctgta tgacatctgg ctgaaaggcg atcactacaa
     8161 atggcgcgct atgcgtacca acggtgtggc cgagcgtctg tgtaccggtg atgcgtctga
     8221 ccgtgaaaaa tttgacgcct gggcggcgac tgttccgcac actatcggca acccgttata
     8281 ccactggacg cacctcgaac tgcgccgtcc gtttggtatc actggcaaat tgctttctcc
     8341 gtcaactgcc gatgaaatct ggaacgaatg taacgaactg ctggcgcagg ataacttctc
     8401 cgcgcgcggc atcatgcagc agatgaacgt gaaaatggtc ggcaccaccg atgacccgat
     8461 cgattctctg gagcatcacg cagagatcgc caaagacggc tctttcacca tcaaagtgct
     8521 gccgagctgg cgtccggaca aagccttcaa catcgaacag gcgaccttta acgactacat
     8581 ggcgaagctg ggcgaagttt ccgataccga cattcgccgc tttgctgacc tgcaaactgc
     8641 cctgaccaaa cgtctggatc acttcgccgc tcacggctgt aaagtgtctg accacgcgct
     8701 ggatgtggtg atgtttgctg aagcgaacga agcggaactg gacagcattc tggcgcgccg
     8761 tctggctggc gaaaccctga gcgagcacga agtggcgcag ttcaaaactg cggtactggt
     8821 gttccttggt gccgaatatg cacgtcgcgg ctgggtacag cagtaccaca ttggcgcgct
     8881 gcgtaataac aacctgcgtc agttcaaact gctggggccg gatgtaggct ttgactccat
     8941 caacgaccgt ccgatggcgg aagagctgtc taagttgctg agcaagcaga atgaagaaaa
     9001 cctgctgccg aaaaccattc tgtactgcct gaacccgcgc gataacgaag tgctgggcac
     9061 catgatcggt aacttccagg gcgaaggtat gccgggcaaa atgcagttcg gttccggctg
     9121 gtggtttaac gatcagaaag acggtatgga acgtcagatg acccaactgg cgcagctcgg
     9181 tctgctgagc cgctttgtcg gtatgctgac tgacagccgt agcttcctgt catacacccg
     9241 tcacgaatac ttccgccgca ttctgtgcca gatgatcggt cgctgggtgg aagcgggcga
     9301 agcaccggcg gacatcaacc tgctgggcga gatggtgaaa aatatttgct ttaacaatgc
     9361 gcgtgactac ttcgccattg aactgaacta aggtctgggg ttgatatgca atacatcaag
     9421 atccatgcgc tggataacgt cgcggtcgct ttagcagatt tggctgaagg cacagaagtc
     9481 agtgtcgata accagactgt tacgctgcgc caggatgttg ctcgtggaca taaatttgcg
     9541 ttaacggata tcgcaaaagg ggccaatgtc atcaaatatg gcctgccgat tggttatgca
     9601 ttggcggata ttgcggcagg tgttcacgtt cacgcccaca atacgcgcac gaatctgagc
     9661 gatctggatc agtatcgcta tcaacctgat tttcaggatc tgcctgcgca agcggcagat
     9721 cgtgaagtgc agatctatcg tcgcgctaac ggcgatgtcg gggtgcgtaa tgagctgtgg
     9781 atcctgccaa ccgtgggctg tgtcaacggc atcgcgcggc agatccagaa ccgttttctg
     9841 aaagagacca acaacgccga aggtactgac ggcgtgttcc tcttcagcca cacctacggc
     9901 tgctcacagc tgggcgacga tcacattaat acccgcacca tgctgcaaaa catggtgcgc
     9961 cacccgaacg caggcgcagt gctggtgatt ggtctgggct gtgaaaacaa ccaggttgcc
    10021 gcattccgtg aaacgctggg cgatatcgat cctgaacgcg ttcatttcat gatctgccaa
    10081 cagcaggatg atgagatcga agccggaatc gagcatttgc atcagctgta taacgtgatg
    10141 cgcaacgata aacgcgagcc aggcaaactc agcgaactga agtttggtct ggagtgcggt
    10201 ggttctgacg gtctttctgg tattactgct aacccgatgc tggggcgttt ctctgactac
    10261 gtgattgcta acggcggtac taccgtactg accgaagtgc cggagatgtt tggcgcagag
    10321 cagttgctga tggaccattg ccgcgacgaa gcaacgtttg aaaaactggt caccatggtc
    10381 aacgacttca aacagtactt tattgcccat gatcagccga tctatgaaaa cccatcgccg
    10441 gggaacaaag cgggcggtat caccacgctg gaagacaaat cacttggctg tacccagaaa
    10501 gcgggttcca gcgtcgtggt tgacgtgctg cgttacggcg agcgtctgaa aacgccaggg
    10561 ctgaacttgt taagtgcgcc gggtaacgat gccgtagcga ccagcgccct ggcgggtgcg
    10621 ggctgccata tggtgctgtt cagtactggt cgtggcacgc cgtatggtgg atttgtgccg
    10681 acggtgaaaa tcgccaccaa cagtgaactg gcggcgaaga aaaaacactg gatcgacttt
    10741 gacgcgggtc agttgatcca cggtaaagcg atgccgcagt tgctggaaga atttatcgac
    10801 accatcgttg agtttgccaa cggtaagcaa acctgtaacg agcgtaacga cttccgcgaa
    10861 ctggcgatct tcaaaagcgg cgtaacgcta taaagtcgaa atgagttgtt aataaaaaac
    10921 ggcgtttcat aatgtgaagc gccgtttgct tttccatacc tgctaaggat ttatcatgac
    10981 cgcgtattgg ctggcccagg gcgtgggtgt catcgccttt ctgattggta tcacaacatt
    11041 tttcaatcgt gacgaacgtc gcttcaaaaa gcagctttcg gtctatagcg ccgttattgg
    11101 cgtacatttt tttcttctgg gcacctatcc cgctggtgcc agtgccatcc ttaatgccat
    11161 tcgtacattg attaccttac gcacgcgcag cttatgggta atggcgattt ttattgtgct
    11221 gactggcgga attggcctcg cgaagttcca tcatcctgtc gaactattgc cggttatcgg
    11281 cacgattgtc agtacctggg cgctattccg ctgtaaaggg ctgaccatgc gctgcgtaat
    11341 gtggttttca acgtgttgct gggtgattca caacttctgg gcggggtcga taggcggcac
    11401 gatgattgag ggtagttttc tgcttatgaa tggcctgaat atcattcgtt tctggcggat
    11461 gcagaaaagg ggaattgatc cgtttaaagt tgagaaaacc ccttccgccg tagacgaaag
    11521 gggttaaaca attaattacg cagggcgcta tttgccagac gatcgtcttc tgcctggcaa
    11581 gctgccgcag tgaacagcac gtcagttgaa gagttcagcg cggtttcgca agagtcctgc
    11641 aatacgccga tgataaagcc gacggcaacc acctgcatgg cgatatcgtt cgaaataccg
    11701 aacatattac aggccagtgg gatcagcagc agagaccccc ccgccacgcc ggatgcgcca
    11761 caggcacaca gagaagccac cacgctcaac agcagcgccg tgggcagatc gaccggaata
    11821 cccagcgtat taaccgcagc cagcgtcaac acggtaatag tgattgctgc gcccgccata
    11881 ttgatggtgg ctcccagcgg aatagaaacg gaataggtat cgcgatccag attcagcttt
    11941 tcacacagcg ccatattcac cggaatgttc gctgcagagc tgcgggtgaa gaaggcatac
    12001 acaccgcttt cgcgcaggca cagcagcacc agcgggaacg ggttacgacg aattttccac
    12061 cacaccagca atgggttaac caccagcgcc accagtaaca tacagccaac cagcacgacc
    12121 agcagttgcg cgtagcccca cagtgtggag aaaccggtgg ttgccagggt agaagaaacc
    12181 agcccaaaaa taccaatcgg tgcgaagcga atgaccagtt tcaccataaa ggtaacggca
    12241 ttcgacatat cgttaaccag gtttttggtg gtctcgttac cgtgacgcag tgcgaagccg
    12301 aggccgatcg cccacaccag aatcccgatg tagttacctt tcagcagcgc gtcgatgggg
    12361 ttggaaacca tgctcattac cagcccgcgc atcacttcga caatgcctga cggcggcgaa
    12421 atatcacccg cgctactgga taaatgcagt gtagaaggga aggcaaagct gaagactact
    12481 gcggccagag cagcagagaa ggtgcccagt agatagagga acaaaatagg gcggatattg
    12541 gttttctgcc cgtgctggtg gttagcaata gatgccatca ccagcatcaa caccaggatg
    12601 ggggcaacgg ctttcagtgc gccgacgaac aaagtaccta acagaccaac agcttccgcc
    12661 gcgggttttg agatccatgc cagaagaatc cccagaacaa ggccgaccag gatttgtttt
    12721 accaggctgc catgagccag acgccggaat agccccggtg aacgttgcgt agtcattttt
    12781 cgatcctttc attgtgttgt cgcacatccc tggtgcgttc tgtcgacgca tctttcagga
    12841 tgtaacaaag tgtttgcaag gtcgagtata aggaaagtta cagcttcggg aagcgaaaaa
    12901 tgctggattt taaagagagg tcatattttg aaacttaatg gttacattta tttgacataa
    12961 aaataaagcc aacgtgcggc ttccagactg atgacaacat caaaaaagga ctcggtcagt
    13021 cccctcgccc cgtttgggga gagggttagg gtgaggggaa caggccagca tcggtgcgaa
    13081 aaattaccct caccccgacc ctctccctgg aagggagagg gagaaaacgg tgctcatgtt
    13141 aatgacaggg tacacggctt aggcagatta aaaattatcc accccgctgc ttatcatgcc
    13201 gataattcac ccaggcgttg ataataaacg tcatcaccag aatgccaaac accacgccca
    13261 gcgagacggc gattggaata tggtagaagt cgacaatcag catcttgata ccgataaaca
    13321 ccagaatcac cgccaggcca tatttgagca tcgagaaacg ctctgctacg cccgccagca
    13381 ggaaatacat cgcacgcagg ccgaggatcg caaacaggtt tgaggtcagc acaatgaacg
    13441 ggtcagtggt cacggcgaag atagccggaa tgctatccac ggcgaaaatc acgtcgctca
    13501 attccaccag aatcagtacc agcatcagcg gtgtggcgta cagcaatcca ttcttacgca
    13561 caaagaaatg ctcgttgtcg atggtgtcgg tcatgcgcaa atgaccgcgt agccagcgca
    13621 ccagcggctt gtcgccaatg cctgattcat cttcatgggc gagcgccatc ttcacgccgg
    13681 taaacagcag gaaggcaccg aagatataca ggatccagtc gaactgcgaa attagccagc
    13741 tgccagtgaa gatcatgatg gtacgcagaa caatcgcccc gagcacgcca tacaccagca
    13801 cgcggcgttg taatgccgcc ggaacagaga aatagctgaa caacatcagc cagacaaaga
    13861 cgttatcgac cgccagcgat ttctcaatca gataacctgt gagaaaggcc agtgcctgtg
    13921 gatcggcaac ggcgcgacct tcggtttgca ccagatacca ccagaaagcg gcgttaaaca
    13981 gtaacgacag cgtcacccag accagcgacc aggccgcagc ctgtttcatg gtcatggcat
    14041 gtgccccacg acgcccctgc aacaacaggt cgatagccag cataatggcg acaacaacag
    14101 cgaatccgcc ccatagcaac ggcgtgccga cagtattcat agaagttcct tacacataaa
    14161 aaaacggcca acgtcggaag acgtcagccg ctgcttttta tgcatagacc tcgccttccg
    14221 gcaaggtctc acttacaaca aaaaaggaat acgtctgcgt attcctttcg ggttgcccgg
    14281 tgaccggatg tgttttttca cacatcgtaa tgacgatcga ccggcaatga agttactccc
    14341 ctttgcaggt aacaaagtat gacagaccat tcagccagtc aatggtctgt tacatacctt
    14401 ttacactgtt ttactttggc aattatagtt ttacgctatc tgccggaaaa atcaccccag
    14461 tctggcggcg gatctcggtc agcagtttgg cggtgatgcg actgaccgcc agccctggat
    14521 gatccaccag atgctcatcc accagggtag cgaacagctc tgcttcgtag agcatggtat
    14581 taatatgctg cggctgggtg agatcctgca tttggctgcc acgcggcacg aagcacactt
    14641 tctggcattc agacagtttt tcaatcacca gcgatcctgc ttcgccctga atctcgctcg
    14701 ccaggacaga atcactgact tttgagtgct gcaaggtgac gctgaaatca ccgtaatcca
    14761 tcaccaccac gccctgggcg tcaacgccgc ttgccagcaa actggcggtt gcctgcacgc
    14821 ttttcggctc accaaataac gccaccgccg acgccagaca gtaaaaaccg atatccataa
    14881 ttgaaccgtt agagaatgcc ggattaaagg tgttgggatt ctcaccatcc aggtaacgtt
    14941 gataccgcga ggaatactgg caatagttga aaaagacttt ccgcagtttg ccgactttcg
    15001 gcagcgcctg gcgcaacaaa tgaaagttcg gcaggcaggc ggttttaaat gcctcaaaca
    15061 gcaccacctg attttcccgc gcacaggcaa tggcggcatc cacttccgcc agattcgacg
    15121 ccagcggttt ctcgcaaatc acattaattt tatggctaag gaaaagttgt gtctgggaaa
    15181 aatgcaggga attcgggctg gcaatataca ccgcgtcaat ggcatcgctt tccgccatcg
    15241 cttccagcga ggtaaacaga tgctcgacag aaaaatcatt ggcgaagtgc tgggcctgtt
    15301 caaggctgcg ggaatatacg gcggttaact tgtatttacc gctctcatgg gcggcctcga
    15361 cgaactggcg agtgatccag ttcgtaccaa tcacagcgaa acgtatcata acgcgtggat
    15421 actccataaa gggattctgt cgtcaatgta gcacgccttt ttcatcttcg acgtgcgcag
    15481 atacgcatta tttctgcgcc ggacagccat gctcactaaa cggcccaatc atgaccgaag
    15541 gcccgagata tttcggctgg cgatggagga ttttggcgtc aatcacggcg ctgacacgag
    15601 cgagtttctc ccgcagttga gtataaaaac cgtgcttcat attgaggtct ggcgcgttaa
    15661 aaccgatagc gtcgatgccg tactgttttg ccagccagat ggcgcgttga ttatgaaatt
    15721 cttgcgagat aatggtgata tggttttcac caaaaacctt tttggcacgc actaccgaat
    15781 ccagcgttga gaatccggca tagtcgcaga agatcacttt tgctggtacg cctttagcga
    15841 tcaaagcctg ctgcatacct gatgcttcat cgtaattttt acgtccgtta tcgccactta
    15901 ccagcagcca tttcactttt ccggcgtggt acaacgctgc tgcggtatca atacgtcggg
    15961 taaagtagcg attacccggc ctcgccccca gcaataaacc cacgttacgc gccggaacgg
    16021 cgttgacatc gctccaggtc agctgtttgc tggcgttgac cattacgcga tcggcgataa
    16081 ggatggtcgc tcctgccaca agtaacagta agcaggcaat ctttagagtc cggcgagaaa
    16141 aacaaatacg gagaagaagg cgggcaaatg cgcgcagcat ggtcgttatc cttaacgaaa
    16201 ggggggaggt cgattttagg cgctaaagaa agaaaagata acgcctgaca tcattttcag
    16261 attttgttct gcccaagcga caactgcgtt agccacagtc gggtgtcgaa ctcaagctgg
    16321 tggtactggg gttccatatg acaacacaac tggtaaaacg ctttgttatg ctctttctcc
    16381 ttcaggtgcg ccagctcgtg caccacgatc atgcgcaaaa acggttccgg cgcgttgcga
    16441 aacacggtag cgacgcggat ctccaccttt gctttcagct tgccgccctg cacacgagaa
    16501 acagcggtat gtaacccgag cgcgtttttt agcacatgga tcttattgtc atacatcact
    16561 ttattgatcg gcggggcatt acgcagaaac tgatttttca gatcctgagt atattgccag
    16621 agggctttat cggtggcgta gtcgtgtgtt cccggatagc gttttgccag cacatcgccc
    16681 agacgctgtt cgttaatcag tgttcgcacc tgggaaagta gctgctcggg ataaccctga
    16741 agataagtaa gattgctcat aaccgcccac gaaaaagaga aaaagggtat actcacgcac
    16801 ccttttcagg ggcaatgtcg aaattttatc attcaggagg gccgatgagc cacttagaca
    16861 acggtttccg ttcactgaca ctacaacgtt ttccggcgac ggatgacgtt aacccgctac
    16921 aggcgtggga agcggcggat gaatatttgc tgcaacagtt ggacgacaca gaaatccgcg
    16981 gcccggtgtt gatcctgaat gatgcctttg gtgcgttaag ctgcgcactg gcggaacata
    17041 agccgtacag cattggcgac tcatacatca gtgaactggc gacgcgcgag aatttacgcc
    17101 tcaacgggat tgatgagtcg agcgtgaagt ttctcgacag caccgccgac tacccgcaac
    17161 agccgggtgt ggtgctgatc aaagtgccga aaacactggc attgctggaa cagcaactgc
    17221 gtgcgctgcg caaagtggtc acgtcggata cacgtattat tgccggtgcc aaggcccgtg
    17281 acattcacac ttccacgctg gaactgttcg aaaaagtgct cggcccaacc accaccacgc
    17341 tggcatggaa aaaagcgcgc ctgattaatt gcactttcaa tgaaccgcag ctggccgatg
    17401 cgccgcagac cgttagctgg aagctggaag gtactgactg gactatccac aaccatgcga
    17461 atgtcttctc ccgcaccggg cttgatatcg gcgcgcgctt ctttatgcaa catctgccag
    17521 agaatctcga aggggagatt gtcgatctcg gttgcggtaa tggcgttatt ggtctgacgc
    17581 tgcttgataa aaacccgcag gcgaaagtgg tgtttgtcga tgaatcgccg atggcggttg
    17641 cttccagccg tttgaacgtt gaaaccaaca tgccagaggc gttggatcgc tgcgagttta
    17701 tgatcaacaa cgcgctctcc ggcgtggagc ctttccgctt taatgctgtg ctctgcaacc
    17761 cgccgtttca ccaacaacat gcgctgaccg ataacgtcgc ctgggagatg ttccaccacg
    17821 cccgccgctg cctgaaaatc aacggcgagc tgtatatcgt tgccaaccgt cacctggatt
    17881 acttccataa actgaagaag attttcggca actgcaccac tattgcgacg aataataaat
    17941 ttgtggtact gaaagcggtg aagctgggac gtcgtcggta agattgggag ttacctgccg
    18001 gatgcggcgt aaacgcctta tccggcctac gttcagcacg ttactccagg ccggataaga
    18061 cgcggcaagc gtcgcatccg gcaatgtctg cccagttctg gaatcgcgct tccataaaac
    18121 aaaaaatccc tgtcaccatc gtctacattc tcttgtttag cgtttttcta cgtttattct
    18181 tccgtcacac agataaattc atacgttgcc aatctggcaa cggatgttat catattgcca
    18241 atttgtcaac ggacgtgatg aagaatgcac ctgataactc aaaaagcatt gaaagatgct
    18301 gcggaaaaat acccgcaaca taaaacggag ttggtggctc tggggaacac gattgctaag
    18361 ggatatttca aaaaacctga gtcattaaaa gcagtattcc catctctgga taacttcaaa
    18421 tatctggata agcattatgt tttcaatgtt gggggcaatg aattacgtgt tgtagcaatg
    18481 gtcttttttg aatcgcaaaa gtgctacata cgtgaagtta tgacgcataa agaatacgat
    18541 ttctttaccg ctgttcatcg tactaagggg aaaaaatgat tgcgattgcc gacatcttgc
    18601 aagcaggaga aaagctaact gctgtggcac cttttctggc gggtattcag aacgaggaac
    18661 aatacaccca ggcgctggaa ctggtagatc atctgctgct caacgatcct gaaaacccct
    18721 tgctggatct ggtttgtgcc aaaataaccg cgtgggaaga atcagcgccc gaatttgcgg
    18781 aatttaatgc catggctcaa gccatgcctg gcggtatagc cgtgattcgt acccttatgg
    18841 atcaatatgg tttaaccctt tccgatctgc cggaaattgg cagtaaatct atggtgtcac
    18901 gcgttttgag cgggaagagg aaattaacgc tggaacacgc taaaaaattg gcaacgcgat
    18961 tcggcatttc tcccgccttg tttattgatt aacgcgacgt gccggatgcg ttgcatccgg
    19021 cgcttcaaat aacgatttaa atctccagcg ccagccgtgt tccctgggca attgcccgtc
    19081 gtgcgtccag ctccatagcc acatcgcagc cgccaattaa atgcaccgtt ttcccgctat
    19141 caatcagcgg ttgcgccagc gcgcggtttg gctcttgccc tgcgcagatc accacattgt
    19201 ccactgctaa tacctgcgtt tcgccgttga tcaccacatg cagcccgtca tcgtcaatct
    19261 tctgataact tacgcctggg atcattttca caccccgcga gagcagggtg gtgcgatgga
    19321 tccagccggt ggttttgcct aacccctgtc ctggtttgct ggctttgcgc tggagcatca
    19381 caatctgccg tgggctacgg gggatctgca ttccctgcgg gcttaagcca ccagcctgtt
    19441 gtaggctact gtcgatcccc cattcattac agaacccggc gatattctgg ctggtggatt
    19501 cgcccggctg acttaaatac atcgccgtat caaaaccaat cccgccacaa ccgatgatgg
    19561 caactttgtt gccaaccggc gctttgtcgc gcagtacatc gagataactc aataccttcg
    19621 gatgatcgat cccgtcgatg ggcggagtgc gcggcacgat cccactggcg aggatcgttt
    19681 catcgaaagc ctgtaactga tccgccgtca cggtgtgatt gagttttagc gtcacgcccg
    19741 tcacttcgat catccggcgg taatagcgca gcgtttcgta aaactcctct ttgccgggga
    19801 tctgtttggc gatattaaac tgcccgccaa tctcgctatg agcgtcaaac aatgttacct
    19861 gatgcccacg cgccgccgcg ttaatggcaa acgccagccc agcaggtccc gcaccgacca
    19921 ccgccagatt ttttttctgc acggcgggaa ggattggcat tttggtttcg tggcaggcgc
    19981 gaggattcac caggcacgag gtgactttgc caacgaagat ttgatcgaga caggcctgat
    20041 tgcagccaat acaagtgttg atctcatcgg ctcgtcccga ttgcgctttt gacagcagct
    20101 ccgcatcagc aagaaacggt cgcgccatcg ataccatatc ggcatcgccg cgcgagagaa
    20161 tatcgtcggc aacctgcgga tcgttaatcc ggttggtggt taccagcggc agcgagacgt
    20221 ggcctttcag tttgcgcgtg acccagctaa atgcgccgcg cggcacgggc gtggcaatgg
    20281 tcggaatacg tgcttcatgc cagccaatgc cggtgttgat aatggtcgcg cccgccgctt
    20341 caatggcctg cgccagctct accgtttcgg caaaagtccc gccgtcttcg accaggtcga
    20401 gcatcgacag tcggtagata ataatgaagt cgttgccgac gcgttcgcgc accgcacgca
    20461 ctacttctac agcaaatcgc atccggttgc ggtaatcgcc gccccactgg tcactatgct
    20521 gattggtgcg cagcgtcaga aattcgttga tcaaataccc ttcggaaccc atcacctcta
    20581 caccgtcgta tcctgcctcc cgcgccagtt gcgcgcagcg ggcgaaattg tcgatcagtt
    20641 gcaggatctc ttcatggctt aactcatggg gcacgaaacg gttgatgggg gcctgcaatg
    20701 cggacggggc gaccagatgc ggttggtagc tgtagcgccc ggtatgcaaa atttgcaggg
    20761 ctattttgcc gccttcctga tgtaccgctt cggtaatggt gcgatggtgt gggatctggc
    20821 tggcgtcgtt gagcattgcg ccaccttcca tgccaacgcc tgttaaatct ggtgcaatgc
    20881 cgccgctgac aatcagcgcc acgccgtgac gggcgcgttc ggcataaaac gctgccagcc
    20941 gctcggcacc gtccgggtat tcctccagcc cggtgtgcat tgagcccatc aacacgcggt
    21001 tttttaacgt ggtaaaacct aaatccagcg gggcgaacag cgacgggtag ctcataaaat
    21061 tgtccagtat gtaaaataat tgttatgtgg tcggatgagt tctaatttag ccgtcgccgg
    21121 agaaaaggga aaaggggagt gcggggtttg tgatgggatt caaaaagaat acgcccggtg
    21181 ataacgccgg atgcgacgct tgtcgcgttt tatccaggtt acggaattgc acatgtaggg
    21241 cggataaggc gtccacgccg catccgccag tggcgcggtg cagatgccgg atgcgacgct
    21301 tgtcgcgtct tatccgacct acgggaacgc acatgtaggg cggataaggc gttcacgccg
    21361 catccgccag tggcgcggtg cagttgccgg atgcaacgct tgccgcgttt tatccggcca
    21421 ggaggattgc acatgtaggg cggataaggc gtttacgccg catccgccag cagttgcaaa
    21481 ttattgctta cggaaaaaat cgttatacaa catatacaaa tgcgcggcac tccaggagaa
    21541 atttggtgcg ccttgctgtg cgcctgtcag cgggttgtaa ttttcctgaa ttggtccatc
    21601 ggcggttaac cctttggcgt gccggaagaa cgtatccgcc agcttcaggg catcatcacg
    21661 ataaccgtaa cgctccatcc ctttcagacc aaaccagaac tgatccaccc atacgcgccc
    21721 acgccagtag atatcagcgc caaaagccgg attggttaac gccgccgttc ccagcgggac
    21781 aaaggtgttg aactctttag gatcgagcat caccttcacc accgcgtcgg cattggcctg
    21841 cgttgccgca ccgttaaaca gcggcgacca gccttccggc cctttaccgc gctcaacaat
    21901 cggtttgccc gcgcagccgt tcgccagtgg tttatcttca atacgtacgt catagtagaa
    21961 ctgggtagtc gggtcgaaca tacaggtgtt gatgtagtcc gcgagctgct gtgccaactg
    22021 gcgatagcgt ttggcctctt ctggcttacc gaggatggtt gccatctccg ccagataatg
    22081 gttatcgctg tacatatagc tggcctgatc caccgactcc tgcaatagcg agtagcccag
    22141 caacgttccg tcctgactgc ggttttcggc gaatttcacc gtccagtcgc tacgtttgcc
    22201 gccattagcg acatatttat ccaactgttc tttgtcgata aacccaaaga cggcggcatc
    22261 atcacgcccc gattcccacg atgcagcaac ctgtgccgga atttccagac tgtcgtactg
    22321 gcctttctcc accacgcggg cgtagttgtt cagcccagac tgcgtctctt ctttatcgcc
    22381 ttttttcacc gtaaacagca tctcgccgct ctcagtgttg tgggctttgt cgcgggtcgc
    22441 gccatattcc ggcacgccgt tgccgttgtg atcgcggtta cgtaaccacc agtcgtgata
    22501 ggccaccagt ttcgggtaca tctctgccac ccaggtttta tcttgggtga cgttatacac
    22561 ttccatcacc gaccaggcgg caaggctggg tttggtatta cgttcgttcc agttgccgcc
    22621 atcgccacca cgctcggggc taaggttcca cgctatcagg tcggggacaa agcccacatc
    22681 ctgcggacgc acgctatcgc caggctggat ctgccaggag aagaccgcgc ggatattctc
    22741 tttggcgatg tccggattga aatgcgccat cgcaaacgcc tgcttccagg tatcccacgg
    22801 ccaggtctga ttgccggaga accagcgccc ggtcaccgac ggtgtaacgg tgttaaattt
    22861 caccgcaccg cccggtgagc gccagttacc gttgagcgtt tcgatcgctt tcaccgcgac
    22921 gcgcgtctgt tccggcgtcg catccggatt ggttaaccct ttcttcaggt attcttccct
    22981 gcgttgctgc gaggcggtga gataaaacgc cggacgcgcc agaatatcgc ggatctgcat
    23041 ttgctctttg ctaacttcct gagcggtcag cagatgggaa taggtggtgt agagcgtggt
    23101 cgaaccgttg atatgcgcct tactggtaaa gcgattaccg ttgatttcag tctgcaccgg
    23161 cagggattta tgcacctgat attccgattc gccggaggtc agcagatccc aggtggcgcg
    23221 cactttgcca aaggtgactt tcaggccatc acgggtggcg ctgattttgc gctgatagtc
    23281 agggtattcg ccagcaatgg ttttatcgga aagcggtttc ccttctttcg cttccagttt
    23341 ttccagcagt tcgccgtccc acaccagatc cagcggttta ttgctggtga ttttggtttc
    23401 cagtagtgac gtgcgcggcg tggcgaagcg cagagtcatt tcgacttgca catcttttgc
    23461 tgtcagtttt tgcaccagcg caccgggaat actgtatgcc tccagcgtaa agtcgacttt
    23521 cttgccgtcc tgccagacgg tcaggcggtc gaaattgctg gccataaagt tgatgtactc
    23581 ttccgtcagc agcgcaacgc ccggaaagcc gcccatggtg ttagggccgt ctggcaacag
    23641 atgaccatgc caggctccga gatcgaaaaa cggattaaaa cgctggtgat cgtcgtaatc
    23701 gtaatccttc atgtactgcg gcgcgccagt acggttaatc acgtttttat aattgtcggc
    23761 gttagcggca tgggcggaaa aacttatcag cagagcgcag gttactggcg ttaaaatagt
    23821 ttttattttc atgaaattac agtccttatt accagtagaa atattgcatc aggaagattt
    23881 ggtcgctggg atcgtgagag gcatttttca tgtagaagcg gctatcaaaa gccgtggcga
    23941 aacgtccgcc gccgtattcg taccagatac caaactgcat gaaagaggtg gtttcatcgt
    24001 cagcgtggtc agggcgatgt ttggcgtagg tgtaagcggt ggagagataa acgcccttta
    24061 acgcttcata catggcgctc accatcatcc cactttcact tcccggtacg tccagcccgt
    24121 cggcgcgtcc ggtatggtgc caggcgcgag cggcaaagtt aggagttagc aggcccgtga
    24181 gatagagctg tcctgtgccg tcggtgattt ccagaccgtt catccaggtg atgccttcgg
    24241 caaggtcata ctggatgtaa ccgttcatca ttgccggata ggtgtatttg tcgtcatagc
    24301 gatcgtattt gccaaaatgt agccaggctt tgctttcatc atgatgtccg gcaggagtcg
    24361 cggtgacgct ataacgaaag ttgccgctta agttctgtac cttcagcgca gtcataatgt
    24421 cgcgggtatt gggaatgacg tagcccagat cgggggtgaa atcgccccac cattgcaggt
    24481 catccagcga ggaatcctga cgcagactga gcatgatttc ggtgccatca ttggtacgat
    24541 aaccgccata gaaacggtta attccgccct cgaaaccacc ccagctatgg tctggcaccc
    24601 aggcattgcc gtcgtggtcg gcctgcacgg tccagccttc gccgtaaatc aggccgaacc
    24661 aggagccgta cttcatctcc aggccacctt caatataggt accgtcgctg tatttatgtt
    24721 tattctcacc ctctaaatcc atatatccac caacccctaa ttcgccgtaa aaacgaaatg
    24781 aaggagaaga tgtcgaggta attgcgggtg tttttgtgtc gtcatgttct gccggacgtg
    24841 cttcttctcc tgccgcagaa aaggcgtagc aaaacggcag agcaagtaat gctctgcatg
    24901 gtgcagtgat taatttcatt gtgttaatcc atgagctaaa gaaaaagtac agccttttat
    24961 cgttgtaatt ataaaaatat aaaggcagaa actattttcc ctctcctcat ccaggaagag
    25021 ggaaaatgcc tgctcatttt ttattattct gcttaatcaa cattgctggc tggcgtcgct
    25081 tcaatatggc gctcttcagc cgttaatccc tttatatatt tactgtattt ccaccacgca
    25141 aagccaagga agataacaat accgccgacg ttataaaaaa tgatggtcag aatattcgcg
    25201 ccagtcggga atgtcgaagc gacaaaccct acggcaaata tcgcaatcag cattgaaaca
    25261 acgataatac cggtgcggcg ggagcccata cggaaatcgc gtggcaggtg atctaatttg
    25321 gcgcgtaaat tcaggtaagc cagcatgatg aataacggcg gaagcatgga cgctgcggcg
    25381 gtcatattaa taatagtatt catcagatcc tgcacggtat tggaaccgag catcgggata
    25441 atcatcagcg ggatgacgat caggaactgg atccacgctg cgcgcgccgg aacgccgttt
    25501 tcgttcagtt cgacggtttt cttaccaaag atgccttccg ggatttcgga gaagaaaatt
    25561 ttcaccggcg ttgcggtcca catcagcagg gaaccgaaca tcgcggtaaa ggacaccaga
    25621 ccgacaaagc gattcatcaa cgcttccggt agaccaaaat acgccgccat gccgtggaat
    25681 acctgcaccg atccgccggt aaatttcaac tctttgctgc tgacgaagac gttaatcagc
    25741 accgaggaga cggaatacag tacgccgata aaaatcccgg cgaggatgat cactttaacg
    25801 aacgatttcg aaccgccttt gacgtcgtta acgtacacag cgacggactc cgcgccacct
    25861 gcggccataa agatccaggt ggtaacgccg aggaacgccc agttgaagtt cgggatcatc
    25921 gcgtcaacgg tgatggcgtc agcaggctgt acgccgccaa ccagcgccgt acctgccagt
    25981 aaaatgtagg agagcgttaa cagcagcatc agcgttgaag tgacggaggt aattggcccc
    26041 aacattttcg ccccgttggt ggaaacccag gtggagaagg cgaacagcac catactgata
    26101 atggtggtgg caaccggcgt cataatatat tcgtatccga ggaaggcata cgaagcataa
    26161 gcaataacgc gcggcaacag tgaggtgaaa aagaacaggt ttacgaacca gtaggtatag
    26221 gcagtaataa atgcccaacg tccgcccagc gaacttttta cccacgcgta gacaccggct
    26281 tctgagtttt tatttaacga aacaaattct gcgatgatca gacagaaggg aataaaataa
    26341 aaaatcgtcg cgaggaaaaa catcggtgcc gaggccagtc caagctcaat attattattg
    26401 ataacgttgt taaagctgta aacggcggca aaagtcagcg agagcaagcc gaatttgccg
    26461 attgtattac gtttggtatc agacataaca catctccgaa aatgagtagg gtagcggtgg
    26521 cggcaaactc cttttgccgc cgtagttgtt atttgttatg gaaataacca tcttcgatgg
    26581 tgactttgag aaccactttt ttgaccgcgt tattgcagat aaaccgatac gcttcatgga
    26641 tatcgcaaat aacgatttgc ccttcgtgga cctcaacggt ttctccgcag ccttttaaat
    26701 attcacggtc agtttcatca cgataatatt ccactacctg taatgtctct ttcggcgcat
    26761 attcaatttt ttgctgccct tgcaggtagt aatgcacttc aaaatagcgt cgatgcccgg
    26821 taaatagcgc atcggtcgcg gagtctgtct ccacgcggta agtcaatgag tcaccgatgg
    26881 agtgggcgac gccaggctga atgttgtcga tattttcaat cgcttcaacg cagcgttgcc
    26941 acttcttgcc agaggcgtaa atctggcgga actgttctaa gttatcgatg atcctcattg
    27001 cttattctcg ctgtgcaaat tcgtggaaaa gaaccctgcg ccgaactcat acgacgccag
    27061 gctttgcgcg gtagcttctc cgccagaaac cggcagcaac gtaaagccgt agctgaagtc
    27121 acggaaccag acgcgccagg agtccagcac ctcgctgccc caggagttgg agccgaggcc
    27181 aagcagctgg tgatcgaggt tcagggtgat gtcatcactg cgctgcagct cgttacagtg
    27241 ctgggcagcg tggatgtttt cctgggtata gtgccaggcg ctgaagttaa ttgggcgctg
    27301 cggaaccacc agcagaccgt taccgtggcg gttagtcagt gccgtccagc ggacatgctg
    27361 acggttaccg ttgttctgcg ggaagggata gttctcgaac atggcatcga cggtgctgcg
    27421 ccagatatcg atgatgttag cctgctggct gtcggcgtag ttttcgcccg gtccacgacc
    27481 gtaatacgcc acctgatcgt attcgccgtt aattcccatg gtgaaaccga tgcacggaat
    27541 gatgtgcgga tagtcgccgt aacgctcgcc ggaaagcgcc acgttaacct ggccatcggc
    27601 agcgatgcgc cagatgtagg tgcagcgcat cccgaagtca aacaccggcg gggcaataac
    27661 tgtgcggctg atgatcagca cttcaccatc gctctgttct acggcaaagt cgcgcagatg
    27721 ttcctgcatg atctgcaaat gattcggttg ccacagccct tcgtactcct gcttgtggtt
    27781 gtcgatcatc ggcttgaaga agttgatctt tggctcgcga gtcagcagcg attcgccatt
    27841 cacctgccag gatgtcggtt tgccactcat ttttgagaag gtgatcgcga agttgtagcc
    27901 gcgaacggtg cagctcaaac gatcgtcttc cagcgtcagc ggacgcgcat tatttggtgc
    27961 gaaaggcact ggctgcgcgg tgttttcctt cagcgggaac tgataagtgg cgatagggtg
    28021 tccggcttcg ctgtagcggg tgcgggaatc tttggtcacc gtaatgttga ggaacgcttc
    28081 gcgggcgtcc agctgcggca gcgtgatctg caagggggct tcgctgttcg gcgcaacgtc
    28141 gcgcagttta atctgctgcg tcgcgagcgt ttcaccttcg gcgcgcacct ctgcgtgcag
    28201 ggtgtagtca tcaagcgtgg taaaccacag tttattttcg actttcaact cgccgcgagt
    28261 cagatcccgc gcgtggattt ttaccggcgc gataacctgt ttgtactctt tcaggcccgg
    28321 tcccggcgtc tgatcggaat agatcaaacc atcaagacag aagttatagt tgttgggata
    28381 gtcgccgtag tcgccgccga atttatacca gacattgccg tggtcgtcct gtgcctggat
    28441 cccgtggtcg caccactccc agacataatg accctgaatg caatcgtgct tatagaagac
    28501 gttctggtac tccgtcagcc cgcccggtcc gttccccatc gcatgagcat attcacagat
    28561 gatgcgcggc ttcggatgcg ggtattcacc aaactcattc atcagcggca cgcgggtgta
    28621 catggtggaa ataatatcga ccacttcagc atcgcgatct tcttcgtaat gcaccagtcg
    28681 cgtgtcatcc agcgctttcg ccgcatggta catcgcgcgg atgttacagc catagccgga
    28741 ttcattgccc agcgaccaga tgatgatcga cggatggttt ttctgcgcgt ggatatggcg
    28801 aacaatgcgc tcgacgtaga ctttttccca ctgcggatcg tcggtaatac ggctaatatc
    28861 gccgacatta gcaaagccgt gcgattcgac gtcggtttcc gccatcacaa acaggccgta
    28921 gatatcacac agttcgtaaa aacgcggatc gttcgggtag tgagcggtac gcacggagtt
    28981 gatattgtgc tgcttcatca actggagatc tttctcgacg cgatccattc caacggcgcg
    29041 gcctttgcga tgatcgttgt cgtgacggtt gacgccgtgc agcatcacat aacggttatt
    29101 gatccagaac agaccgtcgc gcactttgat atcacggaag ccaacgcgtt gtggcaccac
    29161 ttccagaacg ttgccgttgg cgtctttcag cgtcatgacc agatggtaaa gataagggga
    29221 ttctgctgac cattgctgcg gctgttcgac agtaaaagca aagctggcgc tggtcagttt
    29281 ttcaattgcc aaatgatcaa tggcgctgct gtgcaccacg cgttcgccat caaacagggt
    29341 atattccagc gtcgtgacga caggggaggc ggcgagattt tccagcacca cttcgcagga
    29401 aagcgtggca tcgcaatagg cttcgtcaaa gtcggtacgc acagtgaaat cgttaatatg
    29461 cgttaggtgt tttccgacca gataaacatc gcggaagatc cccgctgacc accacatatc
    29521 ctggtcttcc acgtaggtag agtccgccca ctgcatcacg cgcacacaca acaggttgtc
    29581 gccggtttta accatcgcgc tgatgtcaaa ctctgcggtc aggcgactgc ccttgctgaa
    29641 acccacatac tgaccgttaa catagacttc aaaataggtt tcgacgccgt caaatttaat
    29701 cagcgtctgt ttaccctgcc agccgtcgct gagggtgaaa atacgttgat aggcaccggt
    29761 tgggttatcg ctggggacaa acggcacatc gatggggaac ggaaaacctt cgtcggtata
    29821 ttgcagtttg ccgtgacctt ccatttgcca catggcgggg acggtaatat gcccccagtc
    29881 agccattaac tcagaggtga aggcttctgg tacttgcagc ggatggtcaa aaaagtggaa
    29941 attccactga ccgcttaagg gcagaaacag gctgctggtt tcgcgggcaa aggtacgcgc
    30001 ttgcgcaaca gaatcatatg aaaaaaagta cgcacgcggc gcaagtcggt tttcgtgggt
    30061 gagctgaatg ttttcccagc gattcatagg gcctcccggt agagagaaat cggaaccatt
    30121 catggtgatg gtagtttgtg taattgctgg ggagtttagt aaaattttta ctaaaaagta
    30181 gcaggtaaat gcatttactt taactggatc acgaaaataa acggcagcac tgtccggcaa
    30241 aaacgattgc cggacagtgt gtaaggggat ttaacgggtc gtgccgcgca gttttaattt
    30301 gctgggaacg aagactaaca gcggcagcgc gcgaccatcg cgggcttttt catacaccag
    30361 gttaacgccc tgacttccca tcatctcgga atggatgcgc acggtggaga gcggcggaaa
    30421 ggtaaatcgc gcggtgggga tatcgttaac gctgataagc gaaatatcct gtgggatgtt
    30481 caggcctcgt tcatgaattg cccgcagtac gccgatagca atggaatcgg aagcaacaaa
    30541 cagtgccttc ggatagtctt cccgcgccag catttgtttt gccagttcat aacccgacga
    30601 actggaaaaa ccgccgcgcc agatatcctc ttcgcgtacc acttgtttca gtcggccata
    30661 ttccgcaaag gcgacctcac gaatatccgc cttgccaggc tcatcttcac cgccaataaa
    30721 accaatacga ttaacgccct ggttgatata gaagtcgatg atttctttac tgatgcgtgc
    30781 cagatcgata tccaccgcat cgtaaccgct gccgggttcg tgaaagtcga taaaacagat
    30841 attgtcggtc aacgcgctgg cagcggcgcg cagggcgggc gtgggtttgc cgacaattaa
    30901 aataccggtg acgtttttaa tgtctggtaa gccgctgtgt tcataacagt tggtgagctc
    30961 gatgcccagc ttttcgcact gggtttcaat gccgtggcgg atcgccagat agtaaggatc
    31021 gttgatctcc agctcctgct ggtagctgta gatagccaga atatggtgtt ggttgactgc
    31081 acctgtctgg agtttacggg cactactggt cttgtactcc agcttttcgg cgatctcgag
    31141 aatgcgatgt ttcgtctctt ctttcacatt caatgtcgga tcgtcattta agaccctgga
    31201 tactgtcgcc agggatacgc cagcttcgat tgcgatgtct tttagtgttg ccatgtttac
    31261 cttttttact ttccctgatg tgcgccccca ttgtagagga agtgcttatc gggtcacctg
    31321 ttttcagtaa ataaagcgcg tttctttgac gctgtaacgg taacacagcg gctcacgaat
    31381 gtgatcacgc ctgcattctc catttttagc ctacaggatt gagaaaaact tttgctatag
    31441 tttagtaaaa ttttacccta agggaggaag caatggaaac cgtggcttac gctgattttg
    31501 cacgtctgga aatgcgcgtc ggaaagattg tggaagtgaa acgccatgaa aacgccgaca
    31561 agctgtacat cgtacaggtt gatgtggggc aaaaaacgct gcaaaccgtg accagcctgg
    31621 tgccgtacta cagcgaagaa gagctgatgg ggaaaacggt ggtggtctta tgcaatctgc
    31681 aaaaagcgaa aatgcgtggt gaaacgtcgg aatgcatgct gttgtgtgcg gaaaccgatg
    31741 acggcagtga aagcgtgctg ttaacgccgg agcggatgat gcctgcgggc gtacgcgtcg
    31801 tataaaaaga tcggatggcg acgtcgtatc gccatccgat ttgatattac gcttcttcga
    31861 cacttactcg catggccgcc agcgccttac gcgccgcttt gatcaccagt tcacactgtt
    31921 caatggtcag tgtcagtggc ggttcaatgc ggatcgtttt ggcgttattg agcgttccgg
    31981 ccaccagtac gcgctggcgg aacatctcgc tggcaaagtt atagccgatt tcgttatcaa
    32041 caaactcaat cgccatcaac atccctttac cacgcgcttc ctgtaccaga tcgggatatt
    32101 cccgcgccag ttgacggaaa ccgtccagca acatatcgcc tttttgctca gcctgagccg
    32161 gtaagttctg ctccagcaac acattgatgg tcgccagcgc cgccgcacag gccagcgggt
    32221 tgccgccaaa ggtggtggta tgcaggaatg ggttgtcgaa cagaactgaa aacacctctt
    32281 cagtggcgat ggtcgcgcca atcggcatca cgccgccgcc gagcgctttg gcaaggcaga
    32341 ggatatccgg ctgtacgttc tcatgctcgc aggcgaacat cttgcccgtg cgccccatgc
    32401 ccgtttgtac ttcatcgagg atcatcagtg cgccgaactc atcgcatagc ttacgtacgg
    32461 cggtgagata gcccggcggc ggcagaatta cgccaccttc accctgaatc ggttcgagga
    32521 tcaccgcagc cacatcatca ccggtttttt tgcactcgtt aagagccgtg cgcatggctt
    32581 cgatattgcc aaacggcaca tgacggaagc ccggcagtaa cggcataaac ggtttgcgga
    32641 aggtcgattt cgccgtggcc gacagcgcgc caagtgattt accgtggaac gcgccgctgg
    32701 tggcaataaa agtaaacttg ccgcgcggtg actggtaagc tttcgccagc ttcagcgctg
    32761 cttcaacgga ctcggtgccg ctattacaga agaagctgta tttcagttta ccgggcgtta
    32821 gcgcagcaag ggttttcgcc aacatcgccc gtaacggatc gagcagctcc tggctgtgca
    32881 gcggttgttt cgcaagttga ttctgtacgg cggaaaccac aactggatta cggtgcccca
    32941 cgttgaaaat tccaaaacct cccaggcagt cgataaactc ctggccctgg gtgtcgacaa
    33001 gcgtatttaa acttcccgct tgccactcta cggctccgta atccccgccg gcggtaacag
    33061 atttgcgata ctctaaaaac cccggattga catgctcttt gaagtattca atcacctctc
    33121 ggttaagtgc tttcatctcc tcatgatcca gcgttcgctt ctcaatgaga ttcagggcgt
    33181 gggcgctgca cgctaaagcc gatgcgctcg aaggtaacct gttcaaaata tgctccggag
    33241 gctcgcgtat cacatgatac cgatttaagt attgcaggga ttgcgccact ccggctgcga
    33301 tcgcgaaaat cgggataaac acaaattcgg ttatcatttg tgcaatattt aatgctatct
    33361 gttaacattt gttgttattt tgcacggttt ttgtcgggta tggatttgat gattgctgcg
    33421 caaatgcacg ttttcagggc aataattgcc tgatttttgg gcaagataat taacgttttc
    33481 gtatagtaac agagtgaaag tattttaaat caaggaatta gatttgtgtt taaatcgcaa
    33541 attgcgatct aaatcaaatt aatcggttaa agataaccgc agcggggccg acataaactc
    33601 tgacaagaag ttaacaacca tataacctgc acaggacgcg aacatgtctt ctcatccgta
    33661 tgtcacccag caaaataccc cgctggcgga cgataccact ctgatgtcca ctaccgatct
    33721 gcaaagctat atcactcatg ctaatgacac ttttgtgcag gtgagcggct ataccttgca
    33781 agagttacaa gggcagccgc acaacatggt gcgtcacccg gatatgccaa aagcggcgtt
    33841 tgcggatatg tggttcaccc tgaaaaaagg ggagccctgg agcggcatcg tgaaaaatcg
    33901 ccgcaaaaat ggtgaccatt attgggtgcg ggccaatgcg gtaccgatgg tgcgcgaggg
    33961 aaaaatcagt ggctatatgt cgattcgtac ccgggcgacg gatgaagaga tcgcggcggt
    34021 ggagccgctg tacaaagcgt tgaacgccgg acgtaccagt aagcgtattc ataaaggcct
    34081 ggtggtgcgt aaaggctggc tgggtaaact gccttcatta ccgcttcgct ggcgggcgcg
    34141 tggagtgatg accctgatgt ttatcttgct ggcggccatg ctttggtttg ttgctgcccc
    34201 ggtggtgacg tatatcctct gtgcgttagt ggtattgttg gcaagcgcct gttttgaatg
    34261 gcagattgtg cgcccgatag aaaatgttgc ccatcaggca ctgaaggtgg cgaccggaga
    34321 acgtaatagt gttgagcatc tgaatcgcag cgatgagctg gggctgacat tacgtgcggt
    34381 agggcaactt ggcctgatgt gccgttggct aattaacgat gtctcaagcc aggtgtccag
    34441 tgtcagaaat ggcagtgaga cgctggcgaa aggcaccgat gaactgaacg aacataccca
    34501 gcagacagtt gataacgttc agcaaacggt ggcgaccatg aaccaaatgg cggcgtcggt
    34561 gaaacagaac tctgccacgg cgtcggctgc cgataaactg tcaatcactg ccagtaatgc
    34621 ggcagtgcag ggtggggagg cgatgaccac ggtgatcaag acaatggacg atatcgccga
    34681 cagtacccag cgcattggca ccattacttc gctgattaac gatattgcgt ttcagaccaa
    34741 tattctggcc ctgaatgcgg cggtggaagc ggcgcgtgcc ggcgaacagg gcaaaggttt
    34801 tgcagtggtg gcaggggaag tgcgtcattt agccagccgc agcgctaatg ctgccaacga
    34861 tattcgcaag ctgattgatg ccagtgctga taaggtgcaa tccggttcgc agcaggtaca
    34921 cgccgccgga cggacgatgg aagatattgt ggcacaggtg aaaaacgtca cccagttgat
    34981 cgcccagatt agccattcaa cgctggaaca ggccgatggg ctttccagcc tgacccgtgc
    35041 agtggatgag cttaacctga tcacccagaa aaatgccgag ctggtggaag agagtgcgca
    35101 ggtgtcggcg atggtgaaac accgcgccag ccgactggaa gacgcggtga cggtactgca
    35161 ttaatcggta tgccggatcc ggcggttgga gcacaatgcc tgatgcgatg ctggcgcatc
    35221 ttatcaggcc tgcggggtgt gtagcgggtg taggccggat aaggcgcgtc aagcgtcgca
    35281 tccggcaatt gcaccgcgcc actggcggat gcggcgatta atccagttgc gtaatatcaa
    35341 aagcggcgcg gtcgatcacc gcaatgatct tttttatttg tgcatcactg atatcgctct
    35401 ggttgacgcg taaatccagc accgctttaa aattatccag cgcccgcttc atttgcgggt
    35461 tctggcgcag cgccgcgcca acgcaacgcg ctttgatgcg ttcttcaatc atctccacct
    35521 gttcgcggtt ttcttccagc cactgcgcgc cttgttcggt cagcgcaatc tgcttcttac
    35581 ctccttcctc ttcgcggatg gtaatcagcg actgctcctg cagaaaatcc agcgttgggt
    35641 agatgacgcc cgggcttggg gtgtaattcc cctgggttag attctcaatc gctttaatca
    35701 attcgtaacc gtggctgtca tcgcgcgaga gaatatccag aatcaccaga cgtaattcac
    35761 cgtgaccaaa gaaacgttgc cgacgaccgc cgccgcgacc gtggcgacca ccgcagcatt
    35821 gaccgtgttc atgctggtga ccgtgtccgc agtgctcgtg ttctgacttc tcacctttgc
    35881 agcagccctc atggcgtggc tggccttcat gtttacaaca cccttcgtga tgatggctca
    35941 tatcagcctc cttttgctta attagatata tctaatttat atctgatatg agcgttcttg
    36001 caagtgtaaa aatgattttt aaacgtggac tcatctcaca cgtaggccgg ataaggcgtt
    36061 cacgccgcat ccggcgttga gtaatgatgc ctgagaagag gcggttcgtc ttatcagacg
    36121 atagacatat cagttctaca aatcgcttgc atttatcatg attaacaatc attatcattt
    36181 gcgagtttta tttagatata tctgattacc atcacgaagg cgataacaat gaataacacc
    36241 ccccgctacc cgcagcgcgt tcgcaatgat ctgcgcttcc gtgaactgac tgtgttacgc
    36301 gttgagcgca tcagcgccgg ttttcagcgc attgtcctcg gcggcgaggc gctggacggt
    36361 tttacatcgc gtggctttga cgatcacagc aaactcttct ttcctcaacc tgacgctcac
    36421 tttgtgccgc caacggtaac ggaagagggc atcgtctggc cggaaggacc acgcccaccg
    36481 tcgcgtgact atacgccgct gtatgacgaa ctacgccatg aactggcgat tgatttcttt
    36541 attcacgacg gtggggtcgc cagcggctgg gcgatgcagg cgcaaccggg cgataaactt
    36601 acggtggcag gtccgcgcgg ttcgctggtg gtgccggaag attacgcgta tcagctgtat
    36661 gtctgcgatg aatccggaat gcccgcattg cgccgccgcc tggaaacgtt gagcaaactt
    36721 gccgttaaac cgcaagttag tgcgctggtt agcgtgcggg ataacgcctg tcaggattat
    36781 ctcgcgcacc ttgatggttt taatatcgaa tggctggcac atgatgagca ggcggtagat
    36841 gcgcgtctgg cgcagatgca aatccctgcc gatgattact tcatctggat aaccggcgaa
    36901 ggtaaagtcg ttaagaattt aagccgccgc tttgaagcgg aacagtatga cccacagcgg
    36961 gtacgtgcag cggcttactg gcacgcaaag taactgatat ataaaaagaa aaaggctgac
    37021 gatttctcgt cagcctttgc tatatctggt ggcccctgct ggacttgaac cagcgaccaa
    37081 gcgattatga gtcgcctgct ctaaccactg agctaagggg ccatggtagc ggattataaa
    37141 gtaactccgt gtcgcaatcc agccattacc gcgcgcctgc tgtttttata aacaatgtat
    37201 tttcaatccg ttatactttt cctggtgatg ttagaaagga gtaaatatgg ttgaggatat
    37261 tttggctcca gggttacggg tcgtgttttg cggtatcaac cctgggcttt catccgccgg
    37321 gactggtttt ccctttgctc atccggcaaa tcgcttctgg aaggtgatat atcaggccgg
    37381 gtttaccgac cgtcagttga agccgcagga ggcacagcat ctgctggatt atcgttgtgg
    37441 cgtcaccaaa ctggtagacc gtccaacggt gcaagccaat gaagtttcaa agcaggagct
    37501 acacgcaggc gggcgtaagc tgattgaaaa aattgaagat tatcagccgc aggcgttggc
    37561 gattctgggc aaacaagcat atgaacaggg attcagccag cgcggtgcac agtgggggaa
    37621 acaaacgctc accattggtt cgacgcagat ttgggtgctg ccaaatccca gcggtttaag
    37681 tcgcgtttca ctggagaaac tggttgaagc gtatcgcgag ctggaccagg cgctggtagt
    37741 gcgtgggcga taaaaaacgc caccgaaaag gtggcgtttg tgcagagggc ctagtgccgg
    37801 gtgcggcgta acgcctgatc cggcctaccg attaatcgtc caggaagcta cgcagcactt
    37861 cagaacggct cgggtgacgc agtttgcgca gcgccttcgc ttcgatctga cggatacgtt
    37921 cgcgggtaac gtcgaactgt ttacccactt cttccagcgt gtggtcggtg ttcatatcga
    37981 taccaaaacg catacgcaga acttttgctt cacgcgcggt caggccagcc agcacgtcgt
    38041 gcgttgccgc acgcaggctt tcggtggtcg cagaatccag cggcagctcg agggtggtat
    38101 cctcgatgaa atcccccaga tgcgaatctt catcatcacc gatcggcgtt tccatggaga
    38161 ttggctcttt ggcgatcttc agcactttgc ggatcttgtc ttccggcatc agcatacgtt
    38221 cagccagttc ttccggcgtc ggttcacggc ccatctcttg cagcatctgg cgagaaatac
    38281 ggttgagctt gttgatggtc tcaatcatat gcaccggaat acggatggtg cgcgcctgat
    38341 ccgcgataga gcgggtgatc gcctgacgga tccaccaggt tgcgtaggtg gagaacttgt
    38401 aaccacggcg gtattcgaat ttatcaaccg ctttcatcag accgatgttg ccttcctgaa
    38461 tcaggtcaag gaactgcaag ccacggttgg tgtatttctt agcgatagaa ataaccagac
    38521 gtaagttcgc ttcaaccatc tctttcttcg cacggcgggc tttcgcttca ccgatggaca
    38581 tacgacggtt gatatcttta acctgctcga tggtcaggcc ggtttcttct tcaatctgct
    38641 gcagtttttg cagggcgcga tgcacttctt cagagacatc gtgcagtttt tccgaccacg
    38701 gcttgttcat cgcaattgcc gcgttgaacc aggtatcgct ggtttcgttg ccggtaaaca
    38761 gggtaatgaa gtttttcttc ggcattttgc actgctcaac gcagagcttc atgatcagac
    38821 gttcttgcgt acgaacgcgg tccatcatga cgcgcatgct gttgaccagg tagtcaaact
    38881 gcttcggcac caggcggaac tgtttgaata cttcagacag tttcaggatc tcttcctgag
    38941 cggtagcgtg actgcgacct ttcgctttga tggtgtcacg cgttacaacg tactgagcgc
    39001 gtagttccgc aaatttttcg cgagccagtt ccgggtcgat gctgttgtca tcatcggcgc
    39061 tgtcgtcatc gccatcttct tcgtcttcat cttcgtcatc gtccagatct tcctgggaaa
    39121 gctcagaacc gacgtgagtg gcggtaggtg ccagatcttc ttctgcgttc gggtcaacaa
    39181 agccggtgat cagatcggac agacgcgctt cttctgcttc aacacgatcg tactgttcca
    39241 gcagataggt gatcgcttcc ggatattcag caacggagca ttgaacctgg ttgatcccgt
    39301 cttcaatacg cttagcgatg tcaatttcgc cttcgcgggt caacagttca acggtgccca
    39361 tttcacgcat gtacatgcgt accgggtcag tcgtgcgccc gatttcagat tccacgctgg
    39421 aaagcacctg cgcggcggct tcggcagcat cttcgtccgc ggtgttttca gccagcatca
    39481 gatcatcggc atccggtgct tcttccatca cctgaatgcc catgtcgttg atcatttgga
    39541 tgatgtcttc gatctgatct gaatcgacga tatcttccgg cagatggtca ttgacctcgg
    39601 cataggtcag atagccttgc tccttaccac gggtgacaag aagtttcagc tgtgactgcg
    39661 ggttttgctc cataagacgg tatccacact tatttcatga ggttggtgtt gggcgattga
    39721 cccgatgtcc ttcagccgtt aacgctgaaa tccaacggtt gtttaccgcc aacgataatt
    39781 acgagggcgt acttatatat ttgccgctgc ctctcagtgc ggctgtcggg ggcttcccga
    39841 tcgctcttcg gcacttaagc cgttaaatca ctttttcgcc agctcctggt ttaatgtcca
    39901 gagctccagg cgttcttcgt tgcttaaacc atgcgtgcgc tcacgagcga ttaactcttc
    39961 ctggcgcagt tcaagcagcg aatcaaacat atggttgagt gagtcggtga aggtttgctc
    40021 agcaatattc ttatctgcta tatcgtccca catcgacagt ttttcaaggg tggcagcatt
    40081 atttgtacca cgatagtgct ctaaaagttg cccggtggtc agacctggct gggagagaca
    40141 agtgttgacc agttctctga ataagccaag tccagggagc ttattttcat ccagattctc
    40201 aagcggcggg accaacgtcg ctaattctgg attttgcacc agcaacccta taagtatacg
    40261 catggtcgtg cgttttagct gcggaacagg gcgagaaacg ccgctctctg ccgcttttgg
    40321 cattaatcgt tcaagctggc tgtcatcaag tatgcctaat ttgttgccta attcctgacg
    40381 aagatatatt cgcagcgttt cgcccggcac ttgcgatatc aatggtagtg ccagcgtact
    40441 caaacgtgcg cgcccgtcag gggtactcag atcaacttgc ggcatcagac tgttaaacag
    40501 aaatgcggag agtggcatcg cctgctccat ccgcgcttca aacgcttctt taccttcttt
    40561 tcgtactagc gtgtcagggt cttcgccatc aggcaaaaac ataaagcgta gctgacggcc
    40621 gtctgtcatg taaggcagcg ccgtttccag cgctcgccag gcggcatcgc ggcctgcacg
    40681 gtcgccgtca taacagcaaa tgacattgtt ggtcgcgcgg aacaacagtt gtatgtgatc
    40741 ggcggtggtt gacgtaccta acgacgcaac ggcgtaatta atgccgtatt gcgccagcgc
    40801 caccacgtcc atatagcctt cgaccacaag cagacgattg ggttcagcgt tatcctgctg
    40861 cgcttcataa agaccgtaaa gctggcggcc tttatggaaa atgtctgttt ccggcgagtt
    40921 caggtatttg ggggtatcgt tgcccagcac gcgcccgcca aaaccaatca cccgaccgcg
    40981 tttatcgcga atggggaaca tcacccgctc gcggaaacga tcgtaactgc gtccctgatc
    41041 gttagtgacc aacatccccg catcaatcaa tgactggcga ttttctggat tgccgccaaa
    41101 ccgcttcagg acgttgtccc agccgggggg cgcaaaacca atcgcaaagc gagcgataac
    41161 ctcgtggctt aatccgcgtt tttccagata ctggcgcgca gacgtggcaa caggttgttg
    41221 taaagattgt tggtaaaacg tattcagacc gtccatcaac tgataaagcg tttgcctctg
    41281 atggcgctcg atctggctgg ggccgctgcc tgcttcaaat ggcacttcaa gattgtgcat
    41341 tgctgccagc tcttcgaccg tttcgacgaa ctcgagcttg tcgtagttca tcaggaagtc
    41401 gatcgcgttg ccgtgcgcgc cacatccaaa gcagtggtaa aactgtttct caccgttaac
    41461 ggtgaaggac ggggttttct cgttgtggaa tggacaacac gcgtggaaat tcttgccctg
    41521 ctttttcagc ttcacacggg catcgatcag atcgacgatg tcagtgcgtg ccagcagatc
    41581 attaatgaat acgcgtggga ttcgtccagc cataggcccc gatttttagc aattcataaa
    41641 cgaaaataag ccgcgcattc ctttcggaag cacggcctta caactacaac tcggtctgat
    41701 cggagagcaa cgctctcggg gaattagtac agacgagtgc ggcgtgcgtt ttcgcgagcc
    41761 agtttcttcg cgtgacgttt cactgcagaa gctttagcgc gcttacgttc ggtagtcggt
    41821 ttttcataga actcacgacg acgaacttcc gccagaacac ctgctttttc gcaggaacgc
    41881 ttgaagcgac gcagagctac gtcgaacggc tcgttttcac gtactttaat taccggcatg
    41941 tgcctctcac ctttgattaa ttcggtttgc cgctggcatc aacgccagct tatttcaaaa
    42001 tggtgcggaa ttttactgca attgctgctg ctttgtaaag caccgcggcc ttttttgaaa
    42061 gggactttta taagggtgag gagtatacac gaggctttct ccaggggcga acaaagtttt
    42121 acatcaaccc gcattggtcc tacactgcgc ggtaataaag cgaggtaaaa caagtcatgc
    42181 gtgtactggg tattgaaact tcctgcgatg aaaccggcat cgccatttac gacgatgaaa
    42241 aaggtttgtt agccaaccaa ttgtatagtc aggtgaaatt gcacgctgac tacggcggcg
    42301 tcgtgcctga actggcctcc cgcgatcatg tgcgtaaaac cgtaccgttg atccaggcgg
    42361 cgctaaagga gtctggttta acggcaaaag acattgatgc tgtggcctat accgcaggcc
    42421 ctggattagt cggcgcgcta ctggttggcg cgaccgtggg gcgttctctg gcgtttgcct
    42481 gggacgttcc ggcgatccct gtacaccata tggaagggca tctgttagcg ccgatgctgg
    42541 aagataaccc gccggaattt ccgtttgttg cgctgcttgt ttccggcggt catacgcagt
    42601 taatcagcgt gactggcatt ggtcagtacg agctgctcgg cgagtctatc gatgatgccg
    42661 ccggggaagc gtttgataaa accgcgaagc tgctggggct ggattatcct ggcgggccgt
    42721 tactgtcgaa aatggcggct cagggtactg ccgggcgctt tgtcttcccg cgtccgatga
    42781 ccgaccgtcc ggggctggat ttcagcttct ccggcctgaa aaccttcgcg gcaaatacca
    42841 ttcgtgacaa cggcaccgac gaccagacgc gtgctgatat cgcccgcgcc tttgaagatg
    42901 cggtggtcga tacgctgatg attaagtgca agcgggcgct ggatcagacg ggctttaagc
    42961 gactggtcat ggcgggcggc gtgagtgcta accgtacgtt acgggcgaag ctggctgaaa
    43021 tgatgaaaaa acgccgcggc gaagtgttct acgcgcgtcc ggaattttgt actgataacg
    43081 gcgcgatgat cgcctatgcc ggaatggtgc ggtttaaagc aggcgcgacg gcggatctcg
    43141 gcgttagcgt gcgtccgcgc tggccgctgg cggagttacc ggctgcgtaa aactattggg
    43201 tgccggagag caatttccgg caccgtcctc acttaaagca acaccacggg catccacagt
    43261 aagccggtaa tcaccagcaa tacgaggaat atcagcccaa aaatcgcccc cagtcgccag
    43321 taatccgccg ttggcagata accactgccg tagtaaatcg gactggggcc ggtggcgtat
    43381 ggtgtaagaa tgctccccag accaattgcc gcaccaacca tcaggcagaa caccggcagc
    43441 gggatttccg gcatcgccag cgcagcggca atcatcatcg gtgcgagagc ggaggtatac
    43501 gccgtggcgc tggcgaaaaa gtagcgcagt agataaaaca ccacaatcaa cgccaccatc
    43561 accatcgttg gcgaataacc gcttaagctg cctgctaaca gtttgccaaa ccagctaata
    43621 aaaccggtgt tgttgagtcc ggtggcgagg gtgataagcg aggccagcca gaagaaaacg
    43681 ttccacgccg ctttattact gacaatgtcg tcccaactga taatgcgcag aagcagcatc
    43741 agtgccacca cgctgtaacc gaccatcgcg gcatcgatat aatcaccgcc gaaaatccac
    43801 agcaccagcg cgcctaccat cagccccagc atccgttttt cacgcgaaca gagcgggccc
    43861 attgcctgca gttccgtctc tgcccagcgc ggcacctgat cgccagactt cagtaccggc
    43921 gggtacagca cgtaagccag ccagggaacc agcagaacca gtaaaatgct gagcggcaac
    43981 atcccgagga accagtcgcc ccaactcagc gtggcgtgag atgcgctttt catcagtcca
    44041 attaacagca agtttggtgc catcgccgtc aagaaaatgg cgctggtcac gcagtcggca
    44101 acaatcccca tccacatgat gtacgagcca atgctgcgcg aactgctgtc gtttggttgt
    44161 gattgataga gcggtggcag gttacggatg atgggataga taatccccgc accacgcgcc
    44221 gagttggacg gtgttacagg tgcgaggatc agctcggaga acatcaccgc atagccgaga
    44281 aacagcgtgc gatgtcccat ctttttcacc agaatcagcg caatgcggcg tccaagcccg
    44341 gttttttcat agcctgtgcc aaacataaag gcggcgaaaa tcagccagat aaccgaatta
    44401 gaaaaaccgg aaacggccca cgagagggat tttgcagtga atttaaagcc tggctgagcg
    44461 agctgctccg ggctgaacag cagccaggga gagagtatgg cgatgatgga tatacccacc
    44521 atcgccacca cggcacccgg cacgggttcg aggatcagtc caacgatcac gccagtaaaa
    44581 acggcaaagt agagccaggt atggttctcc agccctgcgg gaaccggaag tagagcaata
    44641 atggcgatga ccgccagcgg cgcaagatat cgccaccatt cagtggaagg tttcatcgtg
    44701 ttatgcctgc gaaaaaggag aggggtgagc ctctccggga gggttatttg atgtaatgga
    44761 cgtgctcgca gatctcttcc acgatgggat cgcggcgttc ggcgaacagc tttttgtttt
    44821 cggctatcag gttgttgccg tgggtatcaa tagagacaat cagcgggccg aactctttga
    44881 cccggcagac ccacagtgac tccggcattc cgagctctgt ccagtgcact tcttcaatct
    44941 cttccacctg ggttgccgcc agcaccgcgc agcctgccgg gaaaatcaca tgtagcgcct
    45001 tgaatttctg gcagccttct tcggtcagcg gccccatacc acctttgcca accaccagtt
    45061 tcacgccggt ctgctcaata aattcacgtt caaaactttc catacgcata ctggttgtcg
    45121 ggccgacgga gaccatctcc catttgtcgc cgtttttgcg cacgatgggg ccagcgtgga
    45181 aaatcgcttt gccgttgaga tcgtaaggga tcggacgttt cagttcgatc aaacggcggt
    45241 gacaaacgtc gcggcaggtc accagcgtac cggtcaggta gatcacatcg ccgacgcgaa
    45301 tatcttgcag atcttcagct ttgatcgggg ttgtcaggat ctttttcata acgcgctccg
    45361 ggtgtgagac agattttcaa aggtgagatc ggcatgaacc agcagcgtgc cgcgacgatg
    45421 cgcccagcag ccggtagaga cagcaacgcc gatggttgac ggatggcggg cggcagattc
    45481 gatatgtacg cccatcactg aactgttgcc ggtcagccct tgtggaccaa tccccagacg
    45541 gttgagtcct tcttccaggc gtagctccag ttctgccgct tttggattgg gatggcggct
    45601 gccaatcggg cgcaaaatgg ctttacgcga gagtacggcg gcggtttcca ccgaggtggc
    45661 gatgcccacg cccaccagta ccggtggaca ggcgtttacg gcgagggtgg agatattttc
    45721 gaagacgaat ttcaccacgc cttcgtagcc ttctgacggc attaacactt tcgagcggcc
    45781 aggtagcgtg cagccgccgc ctgccatgta aacttcgatt tccgcatcgt cattgtcggg
    45841 gatgatgtcc caggtgaccc acggtacgcc gctaccggta tttttgccgg tgtttacttc
    45901 gtcaaaaatt tctaccgcat tgtgacgtag tggcgctttg acggttgcct cttccacggc
    45961 ttgtttgagt atgctttgca gctcgccaag cagtgggaag cgggaaccga ctttaacgaa
    46021 gaacataatc tccccggtgt cctgacaggc aggacgattc aggtcaatcg ctttttgcat
    46081 gttgtcgaac atcgtatggt agataatttt ccccatcgac gacgtttcgg catcctttag
    46141 ctgttttagt ttatccacca cgtcatcagg cattcgggta gaaatcatgg cggtaaagtt
    46201 agcgacaatc tctgtcaact tattcactgc ctgttgctta ttactttcgc tcatcatggc
    46261 aactccagtt tttgtatttg tctggaaaaa ttcaccgcca caaactacca ctaaaaatgt
    46321 ggttttatat tttttgccac cgtgaatatg taattaacag ttcgtgaatc aacgcgaaaa
    46381 taagaatgaa tattgcgcca gagcagggaa tggcaatgtt ttgcgaaata cactgcgctt
    46441 atcacaactg cggataatta acgatgctga atagctggcc tttagccaaa gacttgcagg
    46501 tactggtaga aatcgttcac agcgggagtt ttagcgccgc agcggcgacg cttgggcaga
    46561 cgcctgcatt tgtcaccaag cggatccaaa tccttgaaaa tacgctggca acaacgctgc
    46621 tgaaccgctc cgctcgcggc gtggcgctga ctgaaagtgg ccaacgttgt tacgaacatg
    46681 cgttggaaat cctcacccaa tatcagcgac tggtcgatga cgtcacgcaa atcaaaacgc
    46741 gcccggaggg gatgattcgt attggttgca gttttggttt tgggcgcagc catattgcgc
    46801 cagctattac cgaactgatg cgcaattatc ctgagttaca ggtgcatttt gaattgttcg
    46861 atcggcaaat tgatttagtg caggataata ttgatctgga tattcgtatt aatgacgaaa
    46921 ttcctgatta ttatattgcg catcttttga caaaaaataa aagaatatta tgcgcagcac
    46981 ctgagtatct gcaaaaatat ccgcagccac aatccctaca ggaattaagt cgtcatgacg
    47041 gtgatgctgc caacttactg atttagtgta tgatggtgtt tttgaggtgc tccagtggct
    47101 tctgtttcta tcagctgtcc ctcctgttca gctactgacg gggtgatgcg taacggcaaa
    47161 agcactgccg gacatcagcg ctatctctgc tctcattgcc gtaaaacatg gcaactacag
    47221 ttcacttac
//
LOCUS       DAPHKZ010000023        46857 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.023, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000023 DAPHKZ010000000
VERSION     DAPHKZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46857
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.023"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(140..253)
                     /locus_tag="RH288_001390"
     CDS             complement(140..253)
                     /locus_tag="RH288_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HDV4030460.1"
                     /translation="MRRLLHYLINNIREHLMLYLFLWGLLAIMDLIYVFYF"
     gene            complement(301..1419)
                     /gene="solA"
                     /locus_tag="RH288_001391"
     CDS             complement(301..1419)
                     /gene="solA"
                     /locus_tag="RH288_001391"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HDV4030461.1"
                     /translation="MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHH
                     GDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEEDPIFVRSGVINLGPADSTFLAN
                     VAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAK
                     EAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRK
                     VFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERV
                     PFAEVASDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITG
                     LSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ"
     gene            complement(1534..1788)
                     /gene="bssS"
                     /locus_tag="RH288_001392"
     CDS             complement(1534..1788)
                     /gene="bssS"
                     /locus_tag="RH288_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415578.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HDV4030462.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDFQVNEYRRH"
     gene            complement(2076..2321)
                     /gene="dinI"
                     /locus_tag="RH288_001393"
     CDS             complement(2076..2321)
                     /gene="dinI"
                     /locus_tag="RH288_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HDV4030463.1"
                     /translation="MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRY
                     AAANNLSVIGATKEDKQRISEILQETWESADDWFVSE"
     gene            complement(2395..3441)
                     /gene="pyrC"
                     /locus_tag="RH288_001394"
     CDS             complement(2395..3441)
                     /gene="pyrC"
                     /locus_tag="RH288_001394"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDV4030464.1"
                     /translation="MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAA
                     KLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
                     VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRP
                     HLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTAL
                     GSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLV
                     PFLAGETVRWSVKQ"
     gene            complement(3547..4107)
                     /locus_tag="RH288_001395"
     CDS             complement(3547..4107)
                     /locus_tag="RH288_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV4030465.1"
                     /translation="MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSK
                     DIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALP
                     VFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
                     QGEAMAKKLAKGIEVKPGEIVIPFTD"
     gene            complement(4241..4888)
                     /gene="grxB"
                     /locus_tag="RH288_001396"
     CDS             complement(4241..4888)
                     /gene="grxB"
                     /locus_tag="RH288_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HDV4030466.1"
                     /translation="MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVG
                     QKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLL
                     PRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVK
                     PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI"
     gene            complement(4952..6160)
                     /gene="mdtH"
                     /locus_tag="RH288_001397"
     CDS             complement(4952..6160)
                     /gene="mdtH"
                     /locus_tag="RH288_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415583.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HDV4030467.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHR
                     LMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSY
                     MGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKR
                     AARRLLERDA"
     gene            6396..6980
                     /gene="rimJ"
                     /locus_tag="RH288_001398"
     CDS             6396..6980
                     /gene="rimJ"
                     /locus_tag="RH288_001398"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HDV4030468.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSF
                     HACYLGYSIGQKWQGKGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR"
     gene            6991..7638
                     /locus_tag="RH288_001399"
     CDS             6991..7638
                     /locus_tag="RH288_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HDV4030469.1"
                     /translation="MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     ITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRE
                     NRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD"
     gene            7640..8563
                     /locus_tag="RH288_001400"
     CDS             7640..8563
                     /locus_tag="RH288_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDV4030470.1"
                     /translation="MKKLRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALP
                     ICESWRIPYADSLSSLAASCDAVFVHSSTASHFDVVSTLLNAGVHVCVDKPLAENLRD
                     AERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATAASLRMDKHRSNSVGPHDLYFT
                     LLDDYLHVVDTALWLSGGKASLDGGTLLTNDAGEMLFAEHHFSAGPLQITTCMHRRAG
                     SQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVGCARHFIEC
                     VQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE"
     gene            8673..10208
                     /gene="murJ"
                     /locus_tag="RH288_001401"
     CDS             8673..10208
                     /gene="murJ"
                     /locus_tag="RH288_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDV4030471.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPHLKKIGMLVLPR
                     INFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTV
                     SLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     LTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVV
                     AVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFAR
                     RTV"
     gene            complement(10248..10664)
                     /gene="flgN"
                     /locus_tag="RH288_001402"
     CDS             complement(10248..10664)
                     /gene="flgN"
                     /locus_tag="RH288_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HDV4030472.1"
                     /translation="MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITE
                     QKSSLLATLDYLEQLRRKEPNTANSVDISQRWQEITVKTQQLRQMNQHNGWLLEGQIE
                     RNQQALEMLKPHQEPTLYGANGQTSTTHRGGKKISI"
     gene            complement(10669..10962)
                     /gene="flgM"
                     /locus_tag="RH288_001403"
     CDS             complement(10669..10962)
                     /gene="flgM"
                     /locus_tag="RH288_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HDV4030473.1"
                     /translation="MSIDRTSPLKPVSTVQPRETTDAPVTNSRAAKTTASTSTSVTLS
                     DAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN"
     gene            complement(11038..11697)
                     /gene="flgA"
                     /locus_tag="RH288_001404"
     CDS             complement(11038..11697)
                     /gene="flgA"
                     /locus_tag="RH288_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HDV4030474.1"
                     /translation="MLIIKRSVAIIAILFSPLSTASNLTSQLHNFFSAQLAGVSDEVR
                     VSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAM
                     PIARGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAISLRDLSPDQPIQLTQFRQAW
                     RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMVSGQVVSGVVDADGNILIN
                     L"
     gene            11852..12268
                     /gene="flgB"
                     /locus_tag="RH288_001405"
     CDS             11852..12268
                     /gene="flgB"
                     /locus_tag="RH288_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDV4030475.1"
                     /translation="MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDID
                     FASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPTAELQYRIPDQPSLDGNTVDM
                     DRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN"
     gene            12272..12676
                     /gene="flgC"
                     /locus_tag="RH288_001406"
     CDS             12272..12676
                     /gene="flgC"
                     /locus_tag="RH288_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDV4030476.1"
                     /translation="MALLNIFDIAGSALTAQSQRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEPGNPLADAKGYVKMPNVDVVGEM
                     VNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ"
     gene            12688..13383
                     /gene="flgD"
                     /locus_tag="RH288_001407"
     CDS             12688..13383
                     /gene="flgD"
                     /locus_tag="RH288_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HDV4030477.1"
                     /translation="MSIAVTTTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLK
                     NQDPTNPMENNELTSQLAQISTVSGIEKLNTTLGSISGQIDNSQSLQASNLIGHGVMI
                     PGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
                     SFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNSGNTLDLGT
                     YGTTTLDEVRQII"
     gene            13408..14616
                     /gene="flgE"
                     /locus_tag="RH288_001408"
     CDS             13408..14616
                     /gene="flgE"
                     /locus_tag="RH288_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HDV4030478.1"
                     /translation="MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
                     SDPLPTVTPFSASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWQVYTQDSSDP
                     NSIAKTATTLEFNANGTLVDGAMANNIATGAINGAEPATFSLSFLNSMQQNTGANNIV
                     ATTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFANNEGLASEGDNVWS
                     ATQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQD
                     QILNTLVNLR"
     gene            14636..15391
                     /gene="flgF"
                     /locus_tag="RH288_001409"
     CDS             14636..15391
                     /gene="flgF"
                     /locus_tag="RH288_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HDV4030479.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVEGLSLPTRTLVTASTPGADMTPGKMDYTSRPLDVALQQDGWLAVQTADGSEGYTRN
                     GSIQVDPTGQLTIQGHPVIGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
                     LKLVKATGSEVQRGDDGIFRLSAETQATRGPVLQADPTLRVMSGVLEGSNVNAVAAMS
                     DMIASARRFEMQMKVISSVDDNAGRANQLLSMS"
     gene            15563..16345
                     /gene="flgG"
                     /locus_tag="RH288_001410"
     CDS             15563..16345
                     /gene="flgG"
                     /locus_tag="RH288_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HDV4030480.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            16398..17096
                     /gene="flgH"
                     /locus_tag="RH288_001411"
     CDS             16398..17096
                     /gene="flgH"
                     /locus_tag="RH288_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HDV4030481.1"
                     /translation="MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPT
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     NFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            17108..18205
                     /gene="flgI"
                     /locus_tag="RH288_001412"
     CDS             17108..18205
                     /gene="flgI"
                     /locus_tag="RH288_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415598.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HDV4030482.1"
                     /translation="MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDA
                     RTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            18205..19146
                     /gene="flgJ"
                     /locus_tag="RH288_001413"
     CDS             18205..19146
                     /gene="flgJ"
                     /locus_tag="RH288_001413"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HDV4030483.1"
                     /translation="MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMF
                     VQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ
                     PLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
                     QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITT
                     TEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAG
                     YATDPHYARKLTNMIQQMKSISDKVSKTYSMNIDNLF"
     gene            19212..20855
                     /gene="flgK"
                     /locus_tag="RH288_001414"
     CDS             19212..20855
                     /gene="flgK"
                     /locus_tag="RH288_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDV4030484.1"
                     /translation="MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQA
                     NSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTS
                     TSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
                     AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVS
                     VQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLN
                     TGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPA
                     VLQNTKNKGDVAIGATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKV
                     AFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQ
                     ALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSIS
                     GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR"
     gene            20867..21820
                     /gene="flgL"
                     /locus_tag="RH288_001415"
     CDS             20867..21820
                     /gene="flgL"
                     /locus_tag="RH288_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDV4030485.1"
                     /translation="MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPI
                     AASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTL
                     SDDDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTETAPFSEEKGKYVGGAESI
                     KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADS
                     EADKETAAAALDKTNRGLKNSLNNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMS
                     DLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLSK"
     gene            complement(22016..25201)
                     /gene="rne"
                     /locus_tag="RH288_001416"
     CDS             complement(22016..25201)
                     /gene="rne"
                     /locus_tag="RH288_001416"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HDV4030486.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPAAPA
                     QPGLLSRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRD
                     TRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTADEQQAPRRERSRR
                     RNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAV
                     VAPVVEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRS
                     RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQV
                     EEQREQEEVHVQPMVTEVPVAAAIEPVVSAPVVEEVAGVVEAPVQVAEPQPEVVETTH
                     PEVIAAAVTEQPQVITESDVAVAQEVAEQAEPVVEPQEETADIEEVVETAEVVVAEPE
                     VVAQPAAPVVAEVAAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQR
                     PTFAFEGKGAAGGHTATHHASAAPARPQPVE"
     gene            25774..26733
                     /gene="rluC"
                     /locus_tag="RH288_001417"
     CDS             25774..26733
                     /gene="rluC"
                     /locus_tag="RH288_001417"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HDV4030487.1"
                     /translation="MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTG
                     LNRLFLHAAALKFTHPGTGEVMRIEAPMDEGLKRCLQKLRNAR"
     gene            complement(26845..27429)
                     /gene="yceF"
                     /locus_tag="RH288_001418"
     CDS             complement(26845..27429)
                     /gene="yceF"
                     /locus_tag="RH288_001418"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-methyl-GTP pyrophosphatase"
                     /protein_id="HDV4030488.1"
                     /translation="MPKLILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQL
                     VLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTF
                     YTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITL
                     FERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG"
     gene            27628..28149
                     /gene="yceD"
                     /locus_tag="RH288_001419"
     CDS             27628..28149
                     /gene="yceD"
                     /locus_tag="RH288_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HDV4030489.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLNGDAKVTVTLECQRCGKPFTHQVYTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLAMVEDEIILALPVVPVHDSEHCEVSEADMVFGELPEEAQK
                     PNPFAVLASLKRK"
     gene            28201..28374
                     /gene="rpmF"
                     /locus_tag="RH288_001420"
     CDS             28201..28374
                     /gene="rpmF"
                     /locus_tag="RH288_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDV4030490.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            28455..29525
                     /gene="plsX"
                     /locus_tag="RH288_001421"
     CDS             28455..29525
                     /gene="plsX"
                     /locus_tag="RH288_001421"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDV4030491.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDA
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFELLDGGKSGTLR"
     gene            29593..30546
                     /gene="fabH"
                     /locus_tag="RH288_001422"
     CDS             29593..30546
                     /gene="fabH"
                     /locus_tag="RH288_001422"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HDV4030492.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHI
                     AAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDG
                     AGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVT
                     ELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF"
     gene            30562..31491
                     /gene="fabD"
                     /locus_tag="RH288_001423"
     CDS             30562..31491
                     /gene="fabD"
                     /locus_tag="RH288_001423"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDV4030493.1"
                     /translation="MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
                     GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAK
                     ITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPSAMAAALEL"
     gene            31504..32238
                     /gene="fabG"
                     /locus_tag="RH288_001424"
     CDS             31504..32238
                     /gene="fabG"
                     /locus_tag="RH288_001424"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HDV4030494.1"
                     /translation="MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQA
                     ISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANA
                     VAFLASDEAAYITGETLHVNGGMYMV"
     gene            32449..32685
                     /gene="acpP"
                     /locus_tag="RH288_001425"
     CDS             32449..32685
                     /gene="acpP"
                     /locus_tag="RH288_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDV4030495.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            32773..34014
                     /gene="fabF"
                     /locus_tag="RH288_001426"
     CDS             32773..34014
                     /gene="fabF"
                     /locus_tag="RH288_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDV4030496.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
                     AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPEN
                     GAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSS
                     TKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGME
                     YTLCNSFGFGGTNGSLIFKKI"
     gene            34134..34943
                     /gene="pabC"
                     /locus_tag="RH288_001427"
     CDS             34134..34943
                     /gene="pabC"
                     /locus_tag="RH288_001427"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HDV4030497.1"
                     /translation="MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQ
                     RLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATR
                     ILSVTAYPAHYDRLRNEGITLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNAD
                     EALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVE
                     VQASLEESLQADEMVICNALMPVMPVCACGDVSFSSATLYEYLAPLCERPN"
     gene            34946..35968
                     /gene="yceG"
                     /locus_tag="RH288_001428"
     CDS             34946..35968
                     /gene="yceG"
                     /locus_tag="RH288_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HDV4030498.1"
                     /translation="MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTL
                     KPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLL
                     ESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGW
                     FWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKE
                     TAVASERDKVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTI
                     TGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVL
                     KEKNAQ"
     gene            35958..36599
                     /locus_tag="RH288_001429"
     CDS             35958..36599
                     /locus_tag="RH288_001429"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDV4030499.1"
                     /translation="MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGT
                     QLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHD
                     LSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIE
                     QESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA"
     gene            36596..37600
                     /gene="holB"
                     /locus_tag="RH288_001430"
     CDS             36596..37600
                     /gene="holB"
                     /locus_tag="RH288_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDV4030500.1"
                     /translation="MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYAL
                     SRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNTLGVDAVREVTEKLNE
                     HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR
                     LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQ
                     ALAYSVPSGDWYSLLAALNHEQAPARLHWLATLLMDALKRHHGAAQVTNVDVPGLVAE
                     LANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIEHYLQPGVVLPVPHL
                     "
     gene            37611..38408
                     /locus_tag="RH288_001431"
     CDS             37611..38408
                     /locus_tag="RH288_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDV4030501.1"
                     /translation="MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYT
                     PETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR"
     gene            38703..40136
                     /gene="ptsG"
                     /locus_tag="RH288_001432"
     CDS             38703..40136
                     /gene="ptsG"
                     /locus_tag="RH288_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HDV4030502.1"
                     /translation="MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
                     AIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATED
                     AKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNH"
     gene            complement(40196..42385)
                     /gene="fhuE"
                     /locus_tag="RH288_001433"
     CDS             complement(40196..42385)
                     /gene="fhuE"
                     /locus_tag="RH288_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
                     /protein_id="HDV4030503.1"
                     /translation="MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETV
                     IVEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVM
                     ENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
                     VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDG
                     KIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWG
                     GLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQQFADTWQATLNATHSEVE
                     FDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYEL
                     FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTT
                     HMKSLYAATRVTLADPLHLILGARYTNWRVDTLTYSMEKNHTTPYAGLVFDINDNWST
                     YASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQ
                     STGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVN
                     PNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLF
                     TRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGTPRNFSITGTYQF"
     gene            42719..43078
                     /gene="hinT"
                     /locus_tag="RH288_001434"
     CDS             42719..43078
                     /gene="hinT"
                     /locus_tag="RH288_001434"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415621.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HDV4030504.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIP
                     NILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            43081..43458
                     /locus_tag="RH288_001435"
     CDS             43081..43458
                     /locus_tag="RH288_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HDV4030505.1"
                     /translation="MRKGCFGLVSLVLLLLVGCRSHPEIPVNDEQSLVMESSLLAAGI
                     SAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAH
                     SAVTLYGSANFLGAHKVRLYLYL"
     gene            43472..44113
                     /gene="lpoB"
                     /locus_tag="RH288_001436"
     CDS             43472..44113
                     /gene="lpoB"
                     /locus_tag="RH288_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HDV4030506.1"
                     /translation="MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQ
                     PVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRHYDWNGAMQPMVSKMLGADGVTAGSV
                     LLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
                     RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ"
     gene            44094..44918
                     /gene="thiK"
                     /locus_tag="RH288_001437"
     CDS             44094..44918
                     /gene="thiK"
                     /locus_tag="RH288_001437"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HDV4030507.1"
                     /translation="MPFRSNNPITRDELLSRFFPQYHPVTTFNSGLSGGSFLIEHQGQ
                     RFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGAVKTYLPD
                     TNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRP
                     LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYA
                     TRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ"
     gene            44929..45954
                     /gene="nagZ"
                     /locus_tag="RH288_001438"
     CDS             44929..45954
                     /gene="nagZ"
                     /locus_tag="RH288_001438"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HDV4030508.1"
                     /translation="MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRE
                     LVRQIRAASRNRLVVAVDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSD
                     VDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISTRLNQLHERW
                     QEEKAGH"
     gene            45977..46519
                     /locus_tag="RH288_001439"
     CDS             45977..46519
                     /locus_tag="RH288_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV4030509.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
BASE COUNT        11251 a        11641 c        12602 g        11363 t
ORIGIN      
        1 aaagaatctt cataagttta gtgggttcag catcagagat gtctggtgag tgctgtagaa
       61 gcaggaataa tctcattcaa tttttcacgc taaatgaaag ggagattaaa tatttgtcag
      121 tttatgtcag tgcggaaaac taaaaataaa acacatagat cagatccata attgccaaca
      181 atccccagag aaaaagataa agcatcagat gctcgcgaat attattgatg agatagtgca
      241 acagccgacg cattaaatac tcctgtaaaa acggcctcat tctggaggcc gtaatgatga
      301 ttattggaag cgggaaagcc tgaatggcgt caaatcaaaa tcgctttttt tgtcttgcgc
      361 aaaatcggca gctatttccc ctaaaactga cgcaaattta aaaccgtgcc cactcaggcc
      421 ggtaatgagc agtgtattat cgtggccggg tagggtatcg ataataaaat cttcgtcagg
      481 cgaattatca taggtgcagg cagcgccgta caggcagcaa ccgatacccg gcaatacatt
      541 gcgcaagaac gggaaggctt ctgacccatc actggccact tccgcaaacg gaacacgttc
      601 atccgctgaa tggataacct ggcctccgtt atgtttgcca atcttcaacg cgtcgttttc
      661 tgccggaaaa ccataatatt gatcgccatt gggcagttca ccggtaaacg ccgggaattt
      721 attcttcacg ctatagcggc catcggcctg ataccaggca aatactttgc gtacgggctg
      781 gacaggcagc tccgggagca ggtcttttac ccatgttccc gcgcagacaa tcgctttttt
      841 cgcctgatac tcaccgtcag ccgtttcaat agttacgcca tcatcgtcat gacgaattgc
      901 ggtgaccggg cagttgaaca gttgcgcaca gcccgcttcc ttcgccagtt ggatccaggt
      961 tttaatcgcc agttcgctgc gcaaaaaacc ggaatcagtt tcaaataagc cgatgtagtt
     1021 gtccgggacg cgtatttccg gccagcgggc cataatccct tgcgcatcga gcttttcaac
     1081 gttgagttgc cattgttcgg cgctgtgggc gacgttggcg agaaatgtgg aatcagccgg
     1141 gccaaggtta atgacgccag agcgtacaaa aatgggatct tcttcgttgt ggcgggagag
     1201 ttcatcccac agcgtttgcg cgcggaggac cagcgggaca tacttttcgc cttcaccata
     1261 agcatggcga attaatcgcg tatcgccgtg gtggctgccg tgttgatgcg gtggcatatg
     1321 ggcgtcggtc attagcacgt ttaaaccggc gcgggttgca taatacccgg cggcagcgcc
     1381 tacggaaccg ctgccaataa tgatgagatc gtatttcatt tttttctctc tgctctcatg
     1441 gtttaagcag agtaattaac tgaatgcaga tatacaaccc agaaatggta aaggcaccgg
     1501 tgaggtgcct tttgggtgga tggtcatgtc atgttaatga cgccgatact cgtttacctg
     1561 gaaatcaccg gattcaattt tggcgattcc tgcttctaat atcgaaataa attgtctggc
     1621 aacatcagtg gttaaccaga gcgtctgacc aacttcagtc ccttcctgct cggacttatt
     1681 tggggtctgg tagtgcaaac gcaacatcag cgcatcatag ctatcaacgg tgctgatgtc
     1741 ccaccctacg agcggatgag tctgaatgac ttcattattt ttttccatca tggcccccta
     1801 attcgtgtta ctagacaacg ttattcgagg ttcaatgcgt ttttatctga agcaacttca
     1861 gtataccaat aagtaagggt attcaccgaa tttttaaagg gggaaacaga taaatttctg
     1921 cttttaagat ttatatgaac aataaaacag catgtcattc atattttttt agcatattgt
     1981 gcaattattt tgaggaagtg tagaaatttt gtactcaaaa ttcgtaagta aaataaaaaa
     2041 gccggggcga cccggcaaaa aaaaatcact gcatattatt cgctgacaaa ccagtcatcg
     2101 gcgctttccc acgtttcctg gagaatttca ctaatgcgct gtttatcttc ttttgtcgcg
     2161 ccaataaccg ataaattatt cgctgcggca taacgtaccg atacgtggcc ttcattatca
     2221 ggaaacgcat actgaatacg gcgggaaagt tcgccagcca gggcgtcaat agccccagct
     2281 ggcaatggag aagttttcgc tatggtgact tcaattcgca taatagcccc ctgttgaata
     2341 tactggttat ttatacaggt aaaataacct aatgacaaca ggaagctacg atttttattg
     2401 tttaacggac cagcgtaccg tttccccggc gaggaatggc accagcgtgt catcagtcag
     2461 tgcgatgctt tcagcaacct gttgctcttc acgtaccagt tcgatgaatg tgtcgttgac
     2521 cggcaaccca tagaactgcg ggccgtttac agaacagaat gcttcaaagt gctgcaaagc
     2581 attcatttct tcaaagacgg tagcgtaact gcccagcgcg gttggggcgt tgaagcagcc
     2641 cgcgcagccg caactgctct ctttgcgatg acgtgcatgt ggcgcagaat ccgtaccgag
     2701 gaatactcga ttaaaaccgc tggcgaccag ttcacgcaat gcctgttggt gaatattacg
     2761 tttgaggatg ggtagacaat acaggtgcgg acgcacgcct ccaaccagca tatggttgcg
     2821 gttaaacatc agatgctgcg gagtgatggt ggcagccagc cgttcatttc cgtcacggac
     2881 atagtcggca gcatctttgg tggtgatgtg ctcaaaaacg actttcagcg cagtcaggcg
     2941 ctggcgcaga ggttccatca cgctttctat aaagcgcgct tcacgatcaa aaatgtcgat
     3001 atctgcatgt gtcacttcac catgcaccag tagcggcata ccgatttttt ccatgcgctc
     3061 aagtaccggc atgattgcgt caattgacgt cacgccgtgg ctggagttag tggttgcgtt
     3121 tgccgggtaa agttttgcag cggtgaacac gccttcgtta aatccgcgct ccagctcatt
     3181 aggatccagc gaatctgtta aataacaggt catcaatggg gtgaaatcgt gcccggcagg
     3241 tacggcgtca agaatacgct ggcgatacgc cacggcagcc tcaacggtgg tcacgggcgg
     3301 agccagattg ggcattacga tagcccgtcc ataaatttcg ctggtatatg gcacgacagt
     3361 ttttaacatg tcgccatcgc ggaggtgaag gtgccagtcg tctgggcggc ggatctttaa
     3421 tacctgggat ggtgcagtca ttaatctcta tgctccggct gaagggatgt ttttgccgga
     3481 cacaaaggat aagcggaaac gttttccttt gcacgaaaaa taaagggcgc gaatgcgccc
     3541 tcgtgattaa tcagtaaatg gaatgacaat ttcgcctggc ttcacttcaa tgcctttcgc
     3601 cagttttttc gccattgctt cgccctggct gccatcttcg cgcaggacgt aagcaggttg
     3661 ctggttaaag taattgcgta atgcctggtt caaataggga agcaacgttt gcatcaccgt
     3721 ttgcattttt tccggttgta ccgtcgcatc gaccacttcc atctctttca ggaagatcgc
     3781 acctttttct ttatcaaaca cgggcagcgc tttcagcttc agtttcatgg tcgctttctg
     3841 actaccgaac agggagttca tgtccagatt ggcgtctccg gttagggtaa ccttattcgg
     3901 ctcttcgcga ccaatttggc tggtcaggtt tgtcagaaca atatgggcgt cagccacgcc
     3961 gggtaaaccg atatcttttg agaaattatt atgtttcgca agcgactggt taatttcttg
     4021 ttcggtgatg gtgtattggg tgagttgatt acagccaacg agcaggccac tgacgatcaa
     4081 tgcagcggca aataaaaact tgttcatggt agtcctcgac atgaaatctg cgtcaatatc
     4141 ctgacacaac gcagcatgtg tcaccagcga taaactcgcc agcagaaaaa actgaaaacg
     4201 gcggcaaccc gcgaatacag gctgccgcgg cgggtcagga ttaaatcgcc attgatgata
     4261 acaaattgat ttgtgtctgt ttcgccatat tatcgcggta atcagcaacg cggcttggcc
     4321 agttaattcc ggctaccagc gtcagattac gcagtagcgg gaatagctga atatcatctt
     4381 ccgaaagttc gccattcacg gcgttcggtt tgacgatcag tttgtccagc gcacgtaaat
     4441 catcgctgat attcttaatc agaccgtcag agtgggccag caggtcggca aaattacccg
     4501 cgctggcctc tttcttgtcg acgaaatatt tgcgcgcggc gggagtagaa aactcatcaa
     4561 atgccgattt ggcaaaacgc ggcaacagca gtttgttggc gtagccattg accttgcgca
     4621 gccactcttc aatggcaggg gaacgtttgc cggtcagtaa cggtttgccg tcgagtttat
     4681 cgacatagtg aacgatgtcc atgctttctg gcatatagcg gctgtcatct ttttgcagaa
     4741 tgggaacctg tttttgaccg accatccggg tgggtgtttc tgcgtcgtcg ttgagcagaa
     4801 catgtaattc gacggggata tttttcaggc cgaaaatcat gcgggctttg aggcagtaag
     4861 ggcagtgatc gtaaatgtat agcttcacgt gactcctcca tttggctgtc agttcacttt
     4921 cagtatggag gagtcagggg ggagtatcaa atcaggcgtc gcgttcaagc aaacgacgcg
     4981 cggcgcgttt ctggctaaac tgccaaccca gcgcaaggaa agtgaagatg ccaataatgc
     5041 ccagcatcat ccacggaagc tctggctggt gcgccgattt gcccaggtca aacagccagc
     5101 cgccaccgat ataaccaata gcgccgccaa tcgccagacc cagacggcta aaccccatat
     5161 agctgccgcg agctcttgcg tccgccagcg aagcacttaa ggtttcacgc gcaggctcgg
     5221 caatgatcga cccgatataa aacagacaaa tcagggtgaa aagttgttgc aggccgctga
     5281 ccatgcccac cggcatcatg cttaatgaca ttatcaacag cccagccatc aaccggtgtt
     5341 ccagacgaaa atgcttttca ctccagcggg cgatagggta gagcaacgtt aacgacagac
     5401 acgcttcaat ggcatacatc catttaacgg cagagggcgc gccagccacg tcgttgacca
     5461 taattggcag catcagcatc acttgtacag ccagcatgta gtaacccgcc agcgtcagaa
     5521 cataggtgac aaaacgcttg tcacgcatca cgcgggtcat gccttcgcga acgggcgtgc
     5581 gtacggtgga gagtttccat gctggtaaca accacgcatt gaacgccgca catagcacaa
     5641 atagaactgc ccctgtggcg cagaccaggc gaaagtcgta ttgcaacagc cagctcccca
     5701 acaatgcgcc aatgaccgca ccggcactgt cctgcatcat caacagcgag aaaaaacgac
     5761 cacgctgctg tggacggatt aatttcacca ccagcgccga acgcggcgga tcaaacaacg
     5821 tgccaccgag tcccgagagc aggcatgaaa accacaatag ccacggttcg tgggcgatac
     5881 ccattgtggc gaatccggcg gcgcgcatca gcataccggt aacaatcatc ggtttggcac
     5941 caaagcggtc ggcaattgca ccgccgaaaa tacccagacc ttgctgaata aattggcgta
     6001 gaccgagagc aataccgacc atgacggcgg cccagcccat ttgatcaacg aagcggatag
     6061 agatcagcgg gaagacaaca aagaacccca gcacgaccag catattatcg atgagcagga
     6121 aatatttacc caggttcctc gcctgcgaca cgcgggacat ttcccctccc gggaaataaa
     6181 agatgagcac tttctattct gcattgccgc taagactttt cccatcactt cggggacaat
     6241 atttttttat caaaacgtcg ctttgataga gagtttttat caaatatgtg aataatgcag
     6301 aaaatggcat tttggacttt tcacagggtc tggttgcgca ggtatagtaa tacttacagc
     6361 gtattaaaga cgttacggga aggagtaggt atagaatgtt tggctatcgc agtaacgtgc
     6421 caaaagtgcg cttaaccaca gaccgactgg tcgtgcgtct ggtgcatgat cgtgatgcct
     6481 ggcgtcttgc ggattattac gcagagaatc gccatttcct caagccctgg gagccagtgc
     6541 gcgacgaaag ccactgttat ccatcaggct ggcaggccag gctggggatg attaacgaat
     6601 ttcataaaca aggttcagct ttctactttg gcttattcga cccggacgaa aaagagatta
     6661 ttggcgttgc caatttttcc aatgttgttc gtggctcttt tcatgcctgc tatctcggtt
     6721 attcgattgg gcaaaaatgg cagggcaaag gactcatgtt tgaagccctg accgcagcca
     6781 ttcgttatat gcagcgcacc caacatattc atcgcattat ggctaattat atgccgcaca
     6841 ataaacgcag cggtgattta ctggcgcgac tgggttttga aaaagaaggc tatgcgaaag
     6901 actatctgtt gattgatgga caatggcgcg atcacgtact gacggcatta actaccccag
     6961 actggacgcc cggccgctaa ggagaatctc atgaaatatc aacttactgc ccttgaagct
     7021 cgcgtgattg gttgcttgct ggaaaagcag gtgaccacgc cggagcaata cccgctctca
     7081 gtcaatggtg tagtcacggc ctgtaatcag aaaacgaacc gtgaaccggt catgaatctg
     7141 agtgaatccg aagtgcagga acagctggat aatctggtca aacgtcatta tctacgcaca
     7201 gtgagcggtt ttggtaatcg ggtcaccaaa tatgagcaac gtttttgtaa ttcagaattt
     7261 ggcgatctga aactgagcgc agcggaagtg gcgttaatca ccacgttgtt attgcgtggt
     7321 gcccagacgc caggtgaact gcgcagccgc gccgcgcgaa tgtatgaatt cagcgatatg
     7381 gcggaagtgg agtcgacgct ggaacaactg gcaaatcgcg aagatggtcc ttttgtggtg
     7441 cgtctggccc gcgaaccggg taaacgcgaa aaccgctaca tgcatctttt cagtggtgag
     7501 gttgaagatc agccggcggt gacggatatg tcgaacgcgg ttgacggtga tttacaggcc
     7561 cgcgtcgaag ccctggaaat cgaagtggca gaactgaaac agcgtcttga ttcgttgctg
     7621 gcccatctgg gagattaaag tgaaaaaatt acgtatcggc gtagtgggat taggtggcat
     7681 tgcgcaaaaa gcgtggttac cggtgctggc ggcagcgtct gactggacgt tacaaggagc
     7741 ctggtcgcct acgcgcgcga aagccctgcc aatttgtgaa agctggcgca ttccttatgc
     7801 cgattcgtta tccagccttg ccgccagttg cgatgcggtt tttgtgcatt ccagcaccgc
     7861 cagccacttt gacgtggtca gtacgttact caatgcgggg gtacatgtct gtgtcgataa
     7921 accgctggca gaaaatctgc gcgatgctga acggctggtg gaactggcgg cgcggaaaaa
     7981 actgacgttg atggtcggtt ttaaccgtcg tttcgcacca ctctacggtg agttaaaaac
     8041 gcaactcgcc accgcagcct cgctaagaat ggataaacat cgtagcaata gcgtcgggcc
     8101 acacgatctt tatttcacgt tgctggatga ttatctgcat gtggtggata ccgcgctgtg
     8161 gttgtcgggc ggcaaagcct ctctggatgg cggtacgcta ctgactaacg acgctggcga
     8221 aatgctgttt gccgagcacc atttttcggc tggtcctttg cagatcacca cctgtatgca
     8281 tcgccgtgcc ggaagtcagc gtgaaaccgt gcaggccgtg actgacggtg cgctcatcga
     8341 cattacggat atgcgcgaat ggcgtgagga gcgcgggcag ggcgtagtgc ataaaccgat
     8401 tcctggttgg cagagtacgc ttgagcaacg tgggtttgtc ggctgtgcgc ggcacttcat
     8461 tgaatgtgtg caaaaccaga cagttccgca aaccgccggc gaacaggccg tgctggcgca
     8521 acgtatcgtt gacaagatct ggcgcgatgc gatgagtgaa taaaccctgt aacatctggc
     8581 ggtagcaatt caccataatc caggtagact attcgcctct ttcagcgcct gccttgcagg
     8641 cgttttgccc gtgggtctgg attagaacac cgatgaattt attaaaatcg ctggccgccg
     8701 tcagctcgat gaccatgttt tcgcgtgtgc ttggcttcgc acgagacgca attgtcgcca
     8761 gaatctttgg cgcagggatg gcaaccgacg cctttttcgt cgcttttaaa cttcctaact
     8821 tgttacgccg tatctttgcc gaaggggcat tttcccaggc atttgtaccg attctggcgg
     8881 aatataaaag taagcagggt gaagacgcca cgcgggtctt tgtctcttat gtttctggcc
     8941 tgctgacact tgcgctggcg gttgtgacgg tcgctggcat gctcgccgca ccgtgggtga
     9001 tcatggtgac cgcgccaggc ttcgctgaca cagctgacaa atttgccctg accagccagc
     9061 tactaaagat tacctttccc tatatcttgc tgatctccct ggcgtcgctg gtgggagcga
     9121 ttctgaatac gtggaaccgc ttctcgattc cggcgtttgc tccaacactg cttaacatca
     9181 gcatgattgg tttcgcgctg tttgccgcac cgtactttaa cccaccggtg ctggcgctgg
     9241 cgtgggctgt tacggtcggc ggcgtcctgc agctggtgta tcagctaccg cacctgaaga
     9301 agatcggcat gctggtcctg ccgcgcatta acttccacga tgccggagca atgcgcgtgg
     9361 tgaaacagat gggaccggcg atccttggcg tctctgtgag ccagatctcc ttaatcatca
     9421 acaccatttt tgcctcgttt cttgcttccg gttcggtgtc ttggatgtat tacgccgacc
     9481 gcttaatgga gtttccgtcc ggtgtgctgg gcgtggcgct tggcaccatt ttgctgccgt
     9541 cgctgtcgaa aagttttgcc agtggcaatc atgatgaata caaccgtttg atggactggg
     9601 ggttgcgtct ttgtttcctg ttggcgctgc cgagtgcggt tgcgttgggc attctttccg
     9661 gtccgttgac cgtttcgctg ttccagtacg gtaaatttac cgcgtttgat gcgctgatga
     9721 cccagcgggc gttaattgcc tactcggtgg gtttgattgg cctgattgta gtgaaagtgt
     9781 tggctcctgg cttttattcc cgccaggaca ttaaaacgcc agtgaaaatt gccatcgtta
     9841 cgctgatttt aacgcaattg atgaacctgg cgtttattgg tccgttgaaa catgccgggc
     9901 tgtcactttc tattggtctg gcggcgtgtc tgaatgcttc gctgctttac tggcagttgc
     9961 gtaagcagaa aatctttacc ccgcaacccg gctggatggc gtttctgttg cgtctggtgg
    10021 tggcggtact ggtgatgtct ggcgtgcttt taggtatgtt acatatcatg ccggagtggt
    10081 cattgggtac catgccctgg cgtttactgc gtttaatggc ggtcgtgctg gcggggattg
    10141 ccgcgtactt cgctgcactg gcggtactgg gcttcaaagt taaagaattt gcccgccgga
    10201 cggtgtaaca atgcattccg gcctgcagtg caggccggag ataatcttca gatcgaaatc
    10261 tttttaccgc cgcgatgggt tgttgaggtc tgaccgttcg ccccatatag cgtcggttcc
    10321 tgatgcggtt tcaacatttc cagcgcctgt tgattgcgct caatctgtcc ttccagtaac
    10381 cagccgttat gttgattcat ttggcgtagt tgctgcgttt tcacagtaat ttcctgccag
    10441 cgttgactaa tatcaacgct atttgctgta ttgggttctt tcctgcgtaa ctgttcgagg
    10501 taatccagcg tcgccagcag tgagcttttt tgttctgtaa tccattgcaa ctggctgccg
    10561 ttgatctgcc ccatagagag atgttgctgc tcttgatcca ttaccgtttt gagatcgtta
    10621 agcacagcgg acatctggtc gaggatctct gcaagacgtg tcatacgatc agttactctg
    10681 caagtcttgc tgcgcttcgt tgatcagcgc atcggcaatt ttgccggtgt ccatttttag
    10741 ttcaccgtta cgaatcgcca gttttaacgc ttcgacacgt tcaagattga tatcactgct
    10801 gccgggttgc atcagttttg cttgcgcgtc gcttaacgtc acactggtgc tggtggaggc
    10861 ggttgttttt gccgcccggc tgttcgttac cggcgcgtca gtggtttcgc gcggttgaac
    10921 ggtgcttaca ggcttcagag gcgaagtgcg atcaatactc atggtttatt cctcattgag
    10981 ggcgctttta tcatgtgttg cttatttatc ggcaagggac gggtaatctt taacagctta
    11041 caggtttata agaatattcc catctgcatc aacaacgccg ctgactacct gtcccgatac
    11101 catgcgcacc cgcgcattct gtgcgacggc tgcattgttc agcgcctgac cttctgcgtt
    11161 ggcgctaaac ccatcaccgc tggcgatcac attgacgcgt tgtcccgctt ttacccgcca
    11221 tgcctggcga aactgggtta actggatagg ttgatcgggt gatagatcgc gcaggctaat
    11281 ggcatcaaca agttgattga tatccagcac cgtacgcggt ggcagggtat ccagccgtcc
    11341 gcgtttcagt ttgacattgc cagcttccag ctttcctccc cgcgcaatgg gcatcgcggc
    11401 aaccacataa tttcctgtgg cctgtacatt aacctgtaaa tatcgtttgt cgttaccgca
    11461 gcgtgccaac acattcacat tgccccacag gcgggaatta ttgctcatcg aaagcaatgg
    11521 ctgctcgcat ggcggtagta gattgggcgc tgtacgaata gaaacacgaa cctcatcact
    11581 tacccccgcg agttgggcgc taaaaaagtt gtgcaattgc gatgtgagat tgctcgccgt
    11641 acttaacgga ctgaacagta tcgcgatgat cgccacgcta cgttttatta tcagcatttt
    11701 cgcccccagc catttctaca acgtgaattg tacctgtccg caatgaccat caacggcata
    11761 aatagcgacc cattttgcgt ttattccgcc gataacgcgc gcgtaaaggc atttaagctg
    11821 atggcagaat tttgatacct gcggaggaga tatgctcgat aagctcgacg ccgccttacg
    11881 ttttcaacaa gaggcgctca atctgcgcgc ccagcgtcag gaagtgctgg cagcaaacat
    11941 cgccaatgcc gatacccctg gttatcaggc gcgcgatatc gattttgcca gtgaacttaa
    12001 aaaagtcatg caacgtggac gggatgcaac cagtgtggtt gcactgacga tgacctcaac
    12061 gcaacacatt ccggcgcagg cgctgacgcc tcctaccgca gaactgcaat accgtattcc
    12121 ggaccagcct tcgcttgacg gtaataccgt cgatatggat cgcgaacgca cccagtttgc
    12181 cgataacagc ctgcaatacc agatgagcct tagcgcgttg agcgggcaaa tcaaaggcat
    12241 gatgaacgtt ttacagagcg gaaattaacg gatggcactg ctgaatattt ttgatatcgc
    12301 cgggtcggcg ttaactgccc agtcccagcg cctgaacgtg gcggccagta atctggcgaa
    12361 tgctgatagc gtgaccggtc ccgatggaca gccatatcgg gcaaaacagg tggtattcca
    12421 ggttaacgct gcaccaggtg ctgcgacagg cggcgtaaag gttgccgatg ttatagaaag
    12481 tcaggccccg gacaaactgg tttatgaacc gggtaatccg ctggcagatg caaagggcta
    12541 cgtaaaaatg ccgaacgttg atgttgtcgg agagatggtt aacaccatgt cggcgtcacg
    12601 cagctatcag gccaatgttg aagtgctcaa cacggtgaaa agcatgatgc tgaaaaccct
    12661 tacgctcggt caataaagga gaaagctatg tccattgcgg taaccaccac cgatccgaca
    12721 aataccggcg tcagtaccac cagcagtagt tcgctcacgg gcagcaacgc cgcagattta
    12781 caaagcagtt ttctgacttt gctggtggcg cagctgaaaa accaggaccc gaccaatcca
    12841 atggaaaaca acgagctgac gtcgcaattg gcacaaatca gcacggtcag cgggattgaa
    12901 aaactcaata ccacgctcgg atctatttcc ggacagattg ataacagcca gtcgttacag
    12961 gccagtaacc tgatcggtca cggcgtgatg atccccggca ccactgttct tgcgggaacc
    13021 ggcagtgaag aaggggctgt gaccacgacc acgccgtttg gtgttgagct gcaacaggcg
    13081 gcagacaaag ttacggccac catcaccgat aaaaatggcg cggttgtgcg caccattgat
    13141 attggtgaac tgaccgccgg agttcacagt ttcacctggg acggtacgtt gactgatggc
    13201 agcactgcgc cgaacggttc ttacaatgta gcgattagcg ccagtaacgg tggtacacaa
    13261 ctggttgccc agccgctgca gtttgctctg gtgcagggtg tgatccgcgg caacagcggt
    13321 aatacgctgg atctcggcac ttacggcacc accaccctcg acgaagtacg gcagataatt
    13381 taagccttca catttcagga gtcagtcatg gccttttctc aagcggttag cggattaaac
    13441 gctgccgcca ccaacctcga tgttattggc aacaatatcg ccaactccgc cacctacggc
    13501 tttaaatcag gcacggcctc ttttgccgat atgtttgccg gttcgaaagt gggactgggg
    13561 gtaaaagttg ccggtatcac tcaggacttt accgatggca cgaccaccaa caccgggcga
    13621 ggtctggacg ttgctatcag ccagaacggt tttttccgtc tggtagacag caacggttcg
    13681 gtgttctaca gccgtaacgg acaatttaag ctggatgaaa accgtaacct ggtgaatatg
    13741 caaggtttac agctgacggg ttacccggca accggtacgc cgccgactat tcagcaaggg
    13801 gcgaatccga ccaatatttc gatcccgaat accctgatgg cagcgaaaac taccaccacg
    13861 gcatcgatgc agatcaacct gaattccagt gatccgcttc ctactgttac gccattcagc
    13921 gccagcaatg cggatagcta taacaaaaaa ggttcggtga ctgttttcga cagtcagggt
    13981 aatgctcatg acatgagcgt ctactttgtg aagaccgggg ataataactg gcaggtctac
    14041 acccaggata gcagtgatcc aaacagcatt gcgaagacag cgacaacact ggaatttaat
    14101 gctaatggca cattagtgga tggtgcgatg gcgaataata tcgcaaccgg cgcaattaac
    14161 ggtgcagaac ccgccacgtt tagtctgagc ttcctcaact ccatgcagca aaataccggc
    14221 gctaacaata ttgtggcaac cacccagaac ggctacaaac cgggcgatct ggtgagttat
    14281 caaatcaatg atgacggtac ggttgtcggc aactattcca acgaacaaac ccaactgctg
    14341 gggcagattg tactggcgaa ctttgccaac aacgaaggtc tggcatccga aggcgacaac
    14401 gtctggtctg cgacgcaatc ttctggcgtg gcgctgttgg ggacagccgg gacgggaaac
    14461 tttggcaccc tgaccaacgg tgcgctggaa gcgtccaacg tcgatctcag taaagaactg
    14521 gtcaatatga tcgttgccca gcgtaactat cagtctaacg cccagaccat caaaacccag
    14581 gaccagatcc tcaacacgct ggttaactta cgctaatcgc tgacgggata gctcaatgga
    14641 tcacgcaatt tataccgcga tgggagcagc cagccagaca ctgaatcaac aggcggtaac
    14701 cgccagtaat ctggccaatg cctcaacgcc cggttttcgc gcgcagttga atgctttacg
    14761 cgcggtgcca gtggaagggc tttctctgcc cacgcgcacg ttggtcacgg cgtcaacgcc
    14821 gggcgcagat atgacgcccg gcaaaatgga ttacacctcg cgcccgctgg acgtcgcgtt
    14881 gcagcaggat ggctggctgg ccgtgcagac cgctgacggc agcgaagggt atacgcgtaa
    14941 tggcagcatt caggttgatc ccaccgggca actgacaatt caggggcatc cggtgatagg
    15001 cgaggctggg ccaattgctg tgccggaagg ggcggaaatc actattgctg ccgatggcac
    15061 aatctcggcg ctcaatccgg gcgatccggc aaatacggtt gcgccagtag ggcgtcttaa
    15121 actggtgaaa gccacgggca gcgaagtgca gcgcggtgac gacggcattt ttcgtttaag
    15181 cgcagaaacc caggccacgc gtgggccggt actgcaggca gatccaacct tgcgtgtgat
    15241 gtcgggggtt ctggaaggca gtaacgtcaa tgccgttgcg gcaatgagcg acatgattgc
    15301 cagcgcgcgg cgttttgaaa tgcagatgaa ggtgatcagc agcgtcgatg ataacgcagg
    15361 ccgtgccaac caactgctgt cgatgagtta attgaaagga tacatgacaa gtataagttg
    15421 cccgatgcgc aagtttatcg ggtctatggg ggcaatcgca atttatcgat tttgcgagca
    15481 cttgtaggcc ggataaggcg tttacgccgc atccggcaag aagacatatg cactttgtca
    15541 ctaatccact acaggacatt ttatgatcag ttcattatgg atcgccaaaa cgggccttga
    15601 cgcccagcaa accaatatgg acgtcattgc caacaacctg gcaaacgtca gtactaacgg
    15661 ttttaagcgt cagcgcgcgg tgtttgaaga tctgctttat caaaccattc gccagccggg
    15721 ggcacagtct tccgaacaaa ccaccttacc ctccggatta caaatcggca cgggggtacg
    15781 cccggtcgcc actgaacgct tacacagcca gggaaacctg tcgcagacca acaacagcaa
    15841 agatgtcgcg attaaagggc agggcttttt ccaggtgatg ttgccagatg gttcatcagc
    15901 ctatacccgt gacggctctt tccaggtgga tcagaacggg cagctggtga cggctggtgg
    15961 ttttcaggtg cagccagcga tcaccattcc ggcgaatgcg ttaagtatca ccatcggtcg
    16021 tgatggcgtg gtcagcgtaa cccaacaagg ccaggcagct ccggttcagg ttgggcagct
    16081 caatctcacc acctttatga atgacaccgg gctggagagc attggcgaaa acctctacac
    16141 cgaaacgcaa tcctctggtg caccgaacga aagcacgccg ggcctgaacg gcgcgggact
    16201 gctgtatcaa gggtatgttg aaacgtctaa cgtcaacgtg gcggaagaac tggtcaatat
    16261 gattcaggtg caacgcgctt acgaaatcaa cagtaaagcg gtgtccacca ccgatcagat
    16321 gctgcaaaaa ctgacgcaac tctaaggctt aaccggtggc aggttcaccg gtttactgat
    16381 ttttgaagat gatagccatg caaaaaaacg ctgcgcatac ttatgccatt tccagcttgt
    16441 tggtgctttc actaaccggc tgcgcctgga taccctccac gccgctggtg cagggggcga
    16501 ccagtgcaca accggttccc ggtccgacgc ccgtcgccaa cggttctatt ttccagtctg
    16561 ctcagccgat taactatggc tatcaaccgc tgtttgaaga tcgtcgacca cgcaatattg
    16621 gcgatacgct gaccatcgtg ttgcaggaga acgtcagcgc cagcaaaagc tcctctgcga
    16681 atgccagccg tgacggtaaa actaattttg gctttgatac tgtgccgcgc tatttgcagg
    16741 ggctgtttgg taacgctcgt gccgatgtcg aagcctccgg tggtaacacg ttcaacggaa
    16801 agggcggggc caatgccagc aataccttta gcggcacgtt gacggtgacg gttgaccagg
    16861 tactggtcaa cggcaacctg catgtggtgg gtgaaaaaca gattgccatt aatcagggta
    16921 ccgaatttat tcgcttctct ggcgtggtta atccacgcac tatcagcggc agcaataccg
    16981 taccgtctac tcaggtggcg gatgcgcgca ttgaatacgt aggcaatggc tacattaacg
    17041 aagcgcaaaa tatgggctgg ttgcagcgtt tcttccttaa cctgtcgcca atgtaagtga
    17101 ggctgtggtg attaaatttc tctctgcatt aattcttcta ctggtcacga cggcggctca
    17161 ggctgagcgt attcgcgatc tcaccagtgt tcagggggta aggcaaaact cactgattgg
    17221 ctatggtctg gtggtggggc tggatggcac cggtgaccag acaacccaga cgccgtttac
    17281 cacacaaacg cttaataaca tgctctcaca gctgggaatt accgttccga cgggcaccaa
    17341 tatgcagcta aaaaacgtcg ctgcggtaat ggtgacagcg tcacttcctc cgtttggacg
    17401 tcaggggcaa accatcgatg tggtggtttc ttccatggga aatgccaaaa gcttgcgtgg
    17461 aggtacgttg ttgatgacac cgcttaaggg cgttgacagt caggtgtatg cgctggcgca
    17521 gggcaatatt ctggttggcg gcgcaggagc ctccgctggc ggtagcagtg ttcaggttaa
    17581 ccaactgaac ggtggacgga tcaccaatgg tgcggttatt gaacgtgaat tgcccagcca
    17641 gtttggcgtc gggaataccc ttaatttgca acttaacgac gaagatttca gcatggcgca
    17701 gcaaatcgct gacaccatca accgcgtgcg tggatatggc agcgccaccg cgttagatgc
    17761 gcggactatt caggtgcgcg taccgagtgg caacagttcc caggtccgct tccttgccga
    17821 tattcagaat atgcaggtta atgtcacccc gcaggacgct aaagtagtga ttaactcgcg
    17881 caccggttcg gtggtgatga atcgcgaagt gaccctcgac agctgcgcgg tagcgcaggg
    17941 gaatctctca gtaacagtta atcgtcaggc caatgtcagc cagccagata caccgtttgg
    18001 tggtggacag actgtggtta ctccacaaac gcagatcgat ttacgccaga gcggcggttc
    18061 gctgcaaagc gtacgttcca gcgccagcct caataacgtg gtgcgcgcgc tcaatgcgct
    18121 gggcgctacg ccgatggatc tgatgtccat actgcaatca atgcaaagtg cgggatgtct
    18181 gcgggcaaaa ctggaaatca tctgatgatc agcgacagca aactactggc aagtgcggcc
    18241 tgggatgcgc aatcactcaa cgaactaaag gcgaaagcgg gcgaagatcc ggcggcaaat
    18301 atccgtccgg tggcccgtca ggtggaaggg atgttcgtgc agatgatgtt gaaaagcatg
    18361 cgcgacgctt taccaaaaga tggcctgttc agcagcgagc acactcgcct gtataccagt
    18421 atgtatgacc agcagattgc ccaacagatg acggcgggca aaggtctggg gcttgcagag
    18481 atgatggtta aacagatgac gccagaacaa ccattgccag aggagtccac gccagcagca
    18541 ccgatgaaat tcccgctcga aactgtggtg cgttatcaaa atcaggcgct ttcgcagctg
    18601 gtgcaaaagg ccgtgccacg taactacgat gattcgctgc cgggtgacag taaagcattc
    18661 ctcgcgcaac tctcgctgcc cgcccaactg gcaagccagc aaagcggtgt gccacatcat
    18721 ttgatcctcg ctcaggcggc actggaatct ggttgggggc aacggcaaat ccgccgcgaa
    18781 aacggcgagc cgagctataa cctgtttggt gtcaaagcct ctggcaactg gaaagggcca
    18841 gttactgaaa tcaccacgac tgaatatgaa aacggcgaag cgaagaaagt aaaagcgaag
    18901 tttcgcgtct acagctcgta tctggaagcc ttgtcggatt acgttgggct gttaacgcgt
    18961 aacccgcgct acgccgccgt gacgaccgcc gcgagtgcgg aacagggggc gcaggcccta
    19021 caggacgcgg gctatgccac cgatcctcac tatgcccgca aactcaccaa catgattcag
    19081 cagatgaaat cgataagcga caaggtgagc aaaacctaca gtatgaacat tgataatctg
    19141 ttctgaataa ctcaagtccg gcgggtcgct gccgataata ctctgtaatt gaaggcttat
    19201 aaggaacctc catgtccagc ttgattaata acgccatgag cggactgaac gcggcccagg
    19261 cggcgttaaa tacggcaagt aataatatct ccagctataa cgttgccgga tatacccgcc
    19321 aaaccactat tatggcgcag gccaatagca cgttgggcgc tggcggctgg gttggcaatg
    19381 gtgtctacgt ttctggtgtg cagcgtgagt atgatgcgtt tattaccaac cagttacgtg
    19441 cggcgcagac gcaaagtagc ggtctgactg cccgctatga gcagatgtcg aaaatcgaca
    19501 atatgctctc caccagtacc tcttcgctgg caacacagat gcaggatttc ttcaccagcc
    19561 tgcaaacgct ggtgagtaac gcggaagacc cggcagcgcg ccaggcgctg attgggaaat
    19621 cagaaggatt ggtgaatcag tttaaaacca ccgatcaata tctgcgcgac caggacaaac
    19681 aggtcaatat cgcgataggt gccagcgttg atcagatcaa caactacgct aaacaaattg
    19741 ccagcctgaa cgatcaaatc tcgcgcctga caggcgtggg ggcaggggcg tcacctaaca
    19801 atctgctgga tcaacgcgat caactggtga gcgaattaaa ccagattgtt ggtgtagaag
    19861 tcagcgttca ggatggcggc acttataaca tcacgatggc caatggttac tcactggttc
    19921 agggaagtac ggcgcggcaa ctggcggcag ttccttccag cgctgaccct tctcgtacga
    19981 ctgtcgctta tgttgatggg acggcaggca atattgagat cccggagaaa ttactgaata
    20041 ccgggtcgct gggcggcatt ctgacattcc gttctcagga tctggaccag acgcgtaata
    20101 cgcttggaca actggcgctg gcatttgccg aggctttcaa cacccaacac aaagccggat
    20161 ttgatgctaa cggcgatgcc ggtgaagatt tctttgctat cggtaagccc gcggttctgc
    20221 aaaacacgaa aaacaaaggt gacgttgcga tcggtgccac ggtaactgat gcctccgcgg
    20281 tactggcgac agattacaaa atctcgttcg ataataatca gtggcaggtc acccgccttg
    20341 ccagcaatac cacttttacg gtgacgccgg atgccaacgg taaagtggca tttgatggtc
    20401 tggagttgac gtttacagga acgcctgccg ttaacgacag cttcacgctg aaaccagtaa
    20461 gtgacgccat cgtcaacatg gatgtattaa tcaccgacga agcgaaaata gcgatggcga
    20521 gcgaagaaga tgcgggtgat agcgataacc gcaacggtca ggccctgctg gatctgcaaa
    20581 gcaacagtaa aacggtgggc ggtgcgaaat cctttaacga cgcttatgcc tcgttagtga
    20641 gtgatatcgg taataaaacc gcgacgttga aaaccagtag cgccacgcaa ggtaatgtgg
    20701 tgacgcagct ttccaatcag cagcagtcga tttccggtgt caatctcgat gaggagtacg
    20761 gaaatctgca acgttttcag cagtattacc tggcgaatgc gcaggttctg cagacggcaa
    20821 acgcgatttt tgatgcgctg attaacattc gctaagggga gataagatgc gtttcagtac
    20881 acagatgatg taccagcaaa acatgcgtgg tatcaccaat tctcaggcag aatggatgaa
    20941 gtacggcgaa cagatgtcga cgggtaagcg agtcgttaac ccttctgacg atcccattgc
    21001 tgcatcacaa gccgtagttc tctcccaggc acaggcgcaa aacagccagt acacgctggc
    21061 gcgtactttc gccactcaaa aagtgtcact ggaagagagt gtacttagcc aggtcaccac
    21121 tgctatccag aatgctcagg aaaaaattgt ctacgccagc aatggcacct tgagtgacga
    21181 tgaccgggcc tcgctggcta cggatattca ggggcttcgt gaccagttgc tgaatctggc
    21241 aaacaccact gacggtaacg ggcgctacat ttttgccggt tataaaacag agactgcgcc
    21301 gtttagcgaa gagaaaggga aatacgtcgg tggagcagaa agtattaaac aacaggtcga
    21361 tgcttcgcgt tcgatggtga tagggcacac gggtgacaaa attttcgaca gtattaccag
    21421 caacgcggta gcggaaccag acggtagcgc ttctgaaacc aatctttttg ccatgctgga
    21481 tagtgccatc gcagccctga aaacgccggt cgcggatagc gaagcggata aagaaaccgc
    21541 cgctgcggcg ttagataaaa ccaaccgcgg actgaaaaac tcgctgaaca atgtgctgac
    21601 tgttcgcgcg gaattaggca cgcagctgaa cgaactggag tcgctggatt cattaggtag
    21661 cgatcgcgct ttagggcaaa cgcagcagat gagcgatctg gttgatgtgg actggaatgc
    21721 aactatttca tcttacatca tgcagcaaac ggcattgcag gcatcgtata aagcatttac
    21781 cgatatgcag ggattgtcgc tcttccagct cagcaaataa tttcgcttta aaacatatca
    21841 tgaaactggg tatgttttgt ctgcctgctc tgggatcgct ggggcgggca tttttttgcc
    21901 tattttgcat tgttggttag caaggatgcc attcgatgaa ttttaatatg ttgattcaaa
    21961 gatgaaataa aaaagccctg gcagttacca gggcttgatt actttgagct aattattact
    22021 caacaggttg cggacgcgca ggagcggcag aggcatgatg tgttgccgta tgaccacctg
    22081 cggcaccttt accttcgaag gcaaaagtag ggcgctgcca gtcactgtga cgcggtgcct
    22141 ccggaacata ttccggtgct ggagcgcgcg tcattggcgc ggtagcgtgg ttatgctcaa
    22201 cggtgacctc aggttcgacc gcagctaccg tttcaacttc tgctgcgact tcagcgacta
    22261 ctggcgcggc aggttgagca acaacttcag gttcagcaac tacaacctca gcagtttcga
    22321 caacttcttc aatatctgcc gtctcttcct gcggttcaac caccggttct gcttgttctg
    22381 caacttcctg ggctacggca acatcagact cggtaatcac ctgcggctgt tcagttaccg
    22441 cggcagcgat cacttcagga tgcgtcgttt caaccacttc cggttgcggt tcggcaacct
    22501 gaacgggggc ttctacgaca ccggccactt cttcaacaac tggcgcgcta acaaccggtt
    22561 cgatagcggc ggcgacaggg acctcagtca ccatcggctg cacatgtact tcttcctgtt
    22621 cgcgctgctc ttcaacctgt acatcttgcg gacgtacaat tggatagcgg atccagactt
    22681 tgccagaggc cagttccgga gacgcgcacg ctacggtcaa cggcattggc gactgggttg
    22741 gataacgctc gtcacgatag cgacgacgac gctgaccact tacgcgcagg tgacgaggcg
    22801 agcggcgaga acgacgcggc atgccaccgt tgtcacggtt atcagcattg ttctcttctt
    22861 gctgttctgg tgcagtttgc gctacgactg gcagcgggac tttcaccagt tctgtgcgtg
    22921 gagctggcgc ttcctgaaca attggttcgg cagcgacagt ttcttcaacc accggtgcga
    22981 ctaccgcttc ttcggctacg ctttgctcgt aacgcacttt ctgattgagc tgacgctgtt
    23041 tacgacgcgg ctgaaccgga cgtacacgtt cttcctgttc ggtttcctga acagattgct
    23101 cttcaacatt cagcgccttc gcttcttgtt gcgcctgacg tttatcatca ttacggcggc
    23161 ggctacgttc acgacgcggc gcttgctgct cgtcggcggt acgcgctttt tccgttacct
    23221 cagcctgctg acggctctca cgcgtctcgg cagtctgctg ctgtgcctgg cgacgattac
    23281 gacggttttc ttcgcgatta tcgctgcctt cagtacgttc actacgggtg tcgcggcgct
    23341 cattacggtc acggcggttg ttctgacgag gcttgcgacg atcctgttga cgttccggtt
    23401 tcgcttctgc tttcggtgct ggttgctcgg tcggtttggt ttcttcacca ccgctgaaca
    23461 gcgctttcag tgcgccgaag aagcggctca acagcccagg ttgtgcagga gctgctggtg
    23521 ttgccggtgc agctttcggt gctggagcta caacaggcgc ggcaggttca gctggcgttg
    23581 gcgcaggcgg cacatccggc atggcaaagg ttgccagcgc aggttgttcc ggacgcttac
    23641 gttcagcgaa ctcttcttca gacggcagcg ccatcgcttc ttcatgcagc ttcggcagca
    23701 tgtagcttaa ggttggggtt tcttcccctt tacgcacgcg cagcacgtgg tagtgcgggg
    23761 tttccatctg atcgtttggc acaattacac agcgcacacc gtcctgacga gtttcaatgg
    23821 catttaccgc agaacgtttt tcattcagca ggtaagaagc gattggcaca ggaacaatgg
    23881 cgtgaacttc ctgggtgttc tctttcagcg cttcttcttc gatcagacgc agaatagaga
    23941 gcgacagcga ttcgttgtca cgcacggtgc cagtaccaga acaacgcgga caaacgtgat
    24001 gactggattc acccagtgat gggctcaggc gctgacggga catttccagc aggccaaagc
    24061 gagaaatatg gctgatttga atacgcgcac ggtcctgacg caccgcttca cgcagacggt
    24121 tttctaccgc acgctggtgg cgtactggcg tcatgtcgat gaagtcgata acaatcaggc
    24181 cgccgaggtc acgcaggcgc agctgacgag caatctcatc ggcagcttcg aggttagtgt
    24241 taaacgcggt ttcttcgata tcgccgccgc gggtcgcgcg tgcggagttg atgtcgatgg
    24301 ccgttaacgc ttcggtgctg tcgataacaa tggaaccacc agacggcaga cgaacttcac
    24361 gctggaaggc ggactcgatc tgtgactcga tctggtagtg gctgaacagc gggatctcgc
    24421 cggtgtacag tttgattttg ctgctgaaat ccgggcgacc taatgcagcg atatgctgac
    24481 gtgccagttc gagcactttc gggttatcga taaggatttc gccgatgtcc tgacgtaagt
    24541 aatcgcggaa tgcgcgaacg attacgttgc tctcctgatg aatcaggaac ggggccgggc
    24601 ggctttcagc ggcttttttg atggcttccc agtgtttcag acggaagctt aaatcccatt
    24661 gcagcgcctc agcagatttg ccgacgccag cggtgcgcac gataagcccc atgccttccg
    24721 gcagttcaag gcttgccagt gcttctttta attcggtacg gtcgtcgcct tcgatacggc
    24781 gagaaatgcc acccgcgcgc gggttgttcg gcatcagaac cagatagcta cccgccagac
    24841 tgataaaggt ggttaatgcc gcgcctttgt tgccgcgctc ttctttatcg atctgaacaa
    24901 tgacttcctg accttcacgc aacacatctt taatgttggg acgaccatga gcactgtagt
    24961 tagcagggaa atattcgcgg gcaatttctt ttagtgggag gaaaccgtga cgttcagcgc
    25021 cgtaatcaac aaaagcagct tccagactcg gttcaatgcg ggtgatttta cctttgtaga
    25081 tgtttgcctt tttctgctcg tgccctggac tttcgatatc caggtcatac agacgctgcc
    25141 catctacaag ggcaacgcgc aactcttcct gctgagttgc gttgattaac attcttttca
    25201 tcgtaactta ctcattattc ttacattgac gactaagctg cgggcaaagt aacgcctttc
    25261 cgggtgtgaa ccgatggcct cgtgtctagt cgcgtcgcca acctcacggt tatcgtcagc
    25321 tcaaagaggc gcagagtgtc ggttgcccgt ttttcatgcg gaaaaacagc gcaattatca
    25381 aagaaacaga ctgggtatta ctctccagaa atatttccat ctaccggtaa ggactgcaac
    25441 ccgcagcccg ctaactgcct gaaagatcaa tacgtcttac gccattgctg cgtggatgat
    25501 cggtcgggca aaatgggtta ttccgtaaaa tttcttgttt taacaaggat ggacacggaa
    25561 acggcctcat tattccactg caagccttgt tatagcaaga tgacttttac catttatcac
    25621 ccgcttactc acagtttttt cacttcttgc tggtgattgg tttaataacc atcaataaag
    25681 tgatcacgca gtgaagtaat aaggtgcaaa agtaaatata agcatagaaa aatgagtggc
    25741 gcgaatcctg ttggctaatt agaatcgcca accatgaaaa cagagactcc atccgtaaaa
    25801 attgttgcta tcaccgctga cgaagcgggg caacgtatcg ataacttttt gcgtacccaa
    25861 ttgaaaggcg taccaaaaag tatgatttac cgtattttgc gtaaaggcga agtgcgggtg
    25921 aacaaaaaac gtattaagcc tgaatataaa ctcgaagcgg gtgatgaggt gcgtattcca
    25981 ccggttcgcg ttgctgagcg ggaagaagag gcggtttcgc cacatctgca aaaggtggcg
    26041 gcgctggcgg acgtcatctt atatgaagat gatcacatcc tggtgctgaa taaaccttcc
    26101 ggtacggcgg tacatggcgg cagtggttta agcttcggcg ttattgaagg tttgcgggcg
    26161 ttgcgcccgg aagcgcggtt ccttgaactg gttcatcgtc ttgaccggga cacctcaggt
    26221 gttttgctgg tagcgaaaaa acgctcggcg ttgcgttctc tgcatgagca attacgtgaa
    26281 aaagggatgc aaaaagatta cctggcgctg gtgcgcggtc agtggcagtc gcatgtgaag
    26341 agcgttcaag caccgttact gaaaaatatt ctgcaaagcg gcgaacgtat cgtgcgtgtg
    26401 agtcaggaag gcaaaccgtc ggaaacacgc tttaaagtgg aagaacgcta tgcatttgcc
    26461 accctggtgc gttgtagccc ggtaacaggg cgtactcacc agatccgtgt gcatacacaa
    26521 tatgcgggtc atccgattgc ctttgacgat cgctacggtg accgtgaatt tgacaggcag
    26581 ctcactgaag caggcacggg attaaatcgc ctgttcctgc acgctgcagc gttgaagttt
    26641 actcatccgg ggaccggtga ggtgatgcgt atcgaagctc cgatggatga aggtttgaag
    26701 cgttgtttgc aaaagctgcg taacgcgcgc taatacaagc atataaacct gataatgggc
    26761 ggttggcctg ataaggcgtt tacgccgcat caggccgcca gcaccgattg ccggatgcga
    26821 cgtaaccaca tccggcgcaa aaaactatcc catcagcggg tttttccctt cccgacgtaa
    26881 catctgacac agcgcgatta gcggtaaacc aaccagcgtg ttaggatcac gcccctctaa
    26941 acgctcaaac agcgtaatgc caaatccttc actcttaaag ctacccgcgc agtgcagggg
    27001 atgctcttta cgcacgtaat tatcaatctc cgcctcgctc aggtgacgga aatggacgtc
    27061 aaaaggctcc acttctgttt gcagatgccc attcgccgaa ttaaacaacg ccagtccagt
    27121 atagaaggtg acgatattgc cgctggcttt gcgtaattgc agacgggcat tttcttccgt
    27181 taacggttta ccggtgattt cgccatcaag aacacatacc tggtctgaac caataattaa
    27241 atgatccgga taacgtgacg ccagagattg cgctttttct tgtgccagtc gaagcaccaa
    27301 ctgtcgcggt gattcgtcgc tgcgtggggt ttcgtcgacc tctggtgctg cacattcaaa
    27361 agagatttgc agtttttcca gaagagcgcg acgccatggc gaggtggagg ctaaaataag
    27421 tttaggcata tttttttcca tcagatatag cgtattgatg atagccattt taaactatgc
    27481 gcttcgtttt gcaggttgat gtttgttatc agcactgaac gaaaataaag cagtaacccg
    27541 caatgtgtgc gaattattgg caaaaggcaa ccacaggctg cctttttctt tgactctatg
    27601 acgttacaaa gttaatatgc gcgccctatg caaaaggtaa aattacccct gactctcgat
    27661 ccggttcgta cggctcaaaa acgccttgat taccagggta tctatacccc tgatcaggtt
    27721 gagcgcgtcg ccgaatccgt agtcagtgtg gacagtgatg tggaatgctc catgtcgttc
    27781 gctatcgata accaacgtct cgcagtgtta aacggcgatg cgaaggtgac ggtaacgctc
    27841 gagtgtcagc gttgcgggaa gccgtttact catcaggtct acacaacgta ttgttttagt
    27901 cctgtgcgtt cagacgaaca ggctgaagca ctgccggaag cgtatgaacc gattgaggtt
    27961 aacgaattcg gtgaaatcga tctgcttgca atggttgaag atgaaatcat cctcgccttg
    28021 ccggtagttc cggtgcatga ttctgaacac tgtgaagtgt ccgaagcgga catggtcttt
    28081 ggtgaactgc ctgaagaagc gcaaaagcca aacccatttg ccgtattagc cagcttaaag
    28141 cgtaagtaat tggtgctccc cgttggatcg gggataaacc gtaattgagg agtaaggtcc
    28201 atggccgtac aacagaataa accaacccgt tccaaacgtg gcatgcgtcg ttcccatgac
    28261 gcgctgaccg cagtcaccag cctgtctgta gacaaaactt ctggtgaaaa acacctgcgt
    28321 caccacatca ctgccgacgg ttactaccgc ggccgcaagg tcatcgctaa gtaatcacgc
    28381 atctgcgtga tgaagcttag tgaggatttt ccccaggcaa ctggggaaag accaaaccgg
    28441 gcggcgacga taccttgaca cgtctaaccc tggcgttaga tgtcatggga ggggattttg
    28501 gcccttccgt gacagtgcct gcagcattgc aggcactgaa ttctaattcg caactcactc
    28561 ttcttttagt cggcaatccc gacgccatca cgccattact tgctaaagct gactttgaac
    28621 aacgttcgcg tctgcagatt attcctgcgc agtcagttat cgccagtgat gcccggcctt
    28681 cgcaagctat ccgcgccagt cgtgggagtt caatgcgcgt ggccctggag ctggtgaaag
    28741 aaggtcgagc gcaagcctgt gtcagtgccg gtaataccgg ggcgctgatg gggctggcaa
    28801 aattattact caagcccctg gaggggattg agcgtccggc gctggtgacg gtattaccac
    28861 atcagcaaaa gggcaaaacg gtggtccttg acttaggggc caacgtcgat tgtgacagca
    28921 caatgctggt gcaatttgcc attatgggct cagttctggc tgaagaggtg gtggaaattc
    28981 ccaatcctcg cgtggcgttg ctcaatattg gtgaagaaga agtaaagggt ctcgacagta
    29041 ttcgggatgc ctcagcggtg cttaaaacaa tcccttctat caattatatc ggctatcttg
    29101 aagccaatga gttgttaact ggcaagacag atgtgctggt ttgtgacggc tttacaggaa
    29161 atgtcacatt aaagacgatg gaaggtgttg tcaggatgtt cctttctctg ctgaaatctc
    29221 agggtgaagg gaaaaaacgg tcgtggtggc tactgttatt aaagcgttgg ctacaaaaga
    29281 gcctgacgag gcgattcagt cacctcaacc ccgaccagta taacggcgcc tgtctgttag
    29341 gattgcgcgg cacggtgata aaaagtcatg gtgcagccaa tcagcgagct tttgcggtcg
    29401 cgattgaaca ggcagtgcag gcggtgcagc gacaagttcc tcagcgaatt gccgctcgcc
    29461 tagaatctgt atacccagct ggttttgagc tgctggacgg tggcaaaagc ggaactctgc
    29521 ggtagcagga cgctgccagc gaactcgcag tttgcaagtg acggtatata accgaaaagt
    29581 gactgagcgt acatgtatac gaagattatt ggtactggca gctatctgcc cgaacaagtg
    29641 cggacaaacg ccgatttgga aaaaatggtg gacacctctg acgagtggat tgtcactcgt
    29701 accggtatcc gcgaacgcca cattgccgcg ccaaacgaaa ccgtttcaac catgggcttt
    29761 gaagcggcga cacgcgcaat tgagatggcg ggcattgaga aagaccagat tggcctgatc
    29821 gttgtggcaa cgacttctgc tacgcacgct ttcccgagcg cagcttgtca gattcaaagc
    29881 atgttgggca ttaaaggttg cccggcattt gacgttgcag cagcctgcgc aggtttcacc
    29941 tatgcattaa gcgtagccga tcaatacgtg aaatctgggg cggtgaagta tgctctggtc
    30001 gtcggttccg atgtactggc gcgcacctgc gatccaaccg atcgtgggac tattattatt
    30061 tttggcgatg gcgcgggcgc tgcggtgctg gctgcctctg aagagccggg aatcatttcc
    30121 acccatctgc atgccgacgg tagttatggt gaattgctga cgctgccaaa cgccgaccgc
    30181 gtgaatccag agaattcaat tcatctgacg atggcgggca acgaagtctt caaggttgcg
    30241 gtaacggaac tggcgcacat cgttgatgag acgctggcgg cgaataatct tgaccgttct
    30301 caactggact ggctggttcc gcatcaggct aacctgcgta ttatcagtgc aacggcgaaa
    30361 aaactcggta tgtctatgga taatgtcgtg gtgacgctgg atcgccacgg taatacctct
    30421 gcggcctctg tcccgtgcgc gctggatgaa gctgtacgcg acgggcgcat taagccgggg
    30481 cagttggttc tgcttgaagc ctttggcggt ggattcacct ggggctccgc gctggttcgt
    30541 ttctaggata aggattaaaa catgacgcaa tttgcatttg tgttccctgg acagggttct
    30601 caaaccgttg gaatgctggc tgatatggcg gcgagctatc caattgtcga agaaacgttt
    30661 gctgaagctt ctgcggcgct gggctacgac ctgtgggcgc tgacccagca ggggccagct
    30721 gaagaactga ataaaacctg gcaaactcag cctgcgctgt tgactgcatc tgttgcgctg
    30781 tatcgcgtat ggcagcagca gggcggtaaa gcaccggcaa tgatggccgg tcacagcctg
    30841 ggggaatact ccgcgctggt ttgcgctggt gtgattgatt tcgctgatgc ggtgcgtctg
    30901 gttgagatgc gcggcaagtt catgcaagaa gccgtaccgg aaggcacggg cgctatggcg
    30961 gcaatcatcg gtctggatga tgcgtctatt gcgaaagcgt gtgaagaagc tgcagaaggt
    31021 caggtcgttt ctccggtaaa ctttaactct ccgggacagg tggttattgc cggtcataaa
    31081 gaagcggttg agcgtgctgg cgctgcctgt aaagcggcgg gcgcaaaacg cgcgctgccg
    31141 ttaccagtga gcgtaccgtc tcactgtgcg ctgatgaaac cagcagccga caaactggca
    31201 gtagaattag cgaaaatcac ctttaacgca ccaacagttc ctgttgtgaa taacgttgat
    31261 gtgaaatgcg aaaccaatgg tgatgccatc cgtgacgcac tggtacgtca gttgtataac
    31321 ccggttcagt ggacgaagtc tgttgagtac atggcagcgc aaggcgtaga acatctctat
    31381 gaagtcggcc cgggcaaagt gcttactggc ctgacgaaac gcattgtcga caccctgacc
    31441 gcctcggcgc tgaacgaacc ttcagcgatg gcagcggcgc tcgagcttta aaagaggaaa
    31501 atcatgaatt ttgaaggaaa aatcgcactg gtaaccggtg caagccgcgg aattggccgc
    31561 gcaattgctg aaacgctcgc agcccgtggc gcgaaagtta ttggcactgc gaccagtgaa
    31621 aatggcgctc aggcgatcag tgattattta ggtgccaacg gcaaaggtct gatgttgaat
    31681 gtgaccgacc cggcatctat cgaatctgtt ctggaaaaaa ttcgcgcaga atttggtgaa
    31741 gtggatatcc tggtcaataa tgccggtatc actcgtgata acctgttaat gcgaatgaaa
    31801 gatgaagagt ggaacgatat tatcgaaacc aacctttcat ctgttttccg tctgtcaaaa
    31861 gcggtaatgc gcgctatgat gaaaaagcgt catggtcgta ttatcactat cggttctgtg
    31921 gttggtacca tgggaaatgg cggtcaggcc aactacgctg cggcgaaagc gggcttgatc
    31981 ggcttcagta aatcactggc gcgcgaagtt gcgtcacgcg gtattactgt aaacgttgtt
    32041 gctccgggct ttattgaaac ggacatgaca cgtgcgctga gcgatgacca gcgtgcgggt
    32101 atcctggcgc aggttcctgc gggtcgcctc ggcggcgcac aggaaatcgc caacgcggtt
    32161 gcattcctgg catccgacga agcagcttac atcacgggtg aaactttgca tgtgaacggc
    32221 gggatgtaca tggtctgacc gcgatttgca caaaatgctc atgttgcgcg cagtctgcgt
    32281 ggttatgagt aataattagt gcaaaatgat ttgcgttatt ggggggtaag gcctcaaaat
    32341 aacgtaaaat cgtggtaaga cctgccggga tttagttgca aatttttcaa cattttatac
    32401 actacgaaaa ccatcgcgaa agcgagtttt gataggaaat ttaagagtat gagcactatc
    32461 gaagaacgcg ttaagaaaat tatcggcgaa cagctgggcg ttaagcagga agaagttacc
    32521 aacaatgctt ctttcgttga agacctgggc gcggattctc ttgacaccgt tgagctggta
    32581 atggctctgg aagaagagtt tgatactgag attccggacg aagaagctga gaaaatcacc
    32641 accgttcagg ctgccattga ttacatcaac ggccaccagg cgtaagtgaa catctccagg
    32701 cggtcgttcg accgcctgag ttttatcttt ttgtcccact agaatcattt tttccctccc
    32761 tggaggacaa acgtgtctaa gcgtcgtgta gttgtgaccg gactgggcat gttgtctcct
    32821 gtcggcaata ccgtagagtc tacctggaaa gctctgcttg ccggtcagag tggcatcagc
    32881 ctaatcgacc atttcgatac tagcgcctat gcaacgaaat ttgctggctt agtaaaggat
    32941 tttaactgtg aggacattat ctcgcgcaaa gaacagcgca agatggatgc cttcattcaa
    33001 tatggaattg tcgctggcgt tcaggccatg caggattctg gccttgaaat aacggaagag
    33061 aacgcaaccc gcattggtgc cgcaattggc tccgggattg gcggcctcgg actgatcgaa
    33121 gaaaaccaca catctctgat gaacggtggt ccacgtaaga tcagcccatt cttcgttccg
    33181 tcaacgattg tgaacatggt ggcaggtcat ctgactatca tgtatggcct gcgtggcccg
    33241 agcatctcta tcgcgactgc ctgtacttcc ggcgtgcaca acattggcca tgctgcgcgt
    33301 attatcgcgt atggcgatgc tgacgtgatg gttgcaggtg gcgcagagaa agccagtacg
    33361 ccgctgggcg ttggtggttt tggcgcggca cgtgcattat ctacccgcaa tgataacccg
    33421 caagcggcga gccgcccgtg ggataaagag cgtgatggtt tcgtactggg cgatggtgcc
    33481 ggtatgctgg tacttgaaga gtacgaacac gcgaaaaaac gcggtgcgaa aatttacgct
    33541 gaactcgtcg gctttggtat gagcagcgat gcttatcata tgacgtcacc gccagaaaat
    33601 ggcgcaggcg cagctctggc gatggcaaat gctctgcgtg atgcaggcat tgaagcgagt
    33661 cagattggct acgttaacgc gcacggtact tctacgccgg ctggcgataa agctgaagcg
    33721 caggcggtga aaaccatctt cggtgaagct gcaagccgtg tgttggtaag ctccacgaaa
    33781 tctatgaccg gtcacctgtt aggtgcggcg ggtgcagtag aatctatcta ctccatcctg
    33841 gcgctgcgcg atcaggctgt tccgccaacc atcaacctgg ataacccgga tgaaggttgc
    33901 gatctggatt tcgtaccgca cgaagcgcgt caggttagcg gaatggaata cactctgtgt
    33961 aactccttcg gcttcggtgg cactaatggt tctttgatct ttaaaaagat ctaagttgtc
    34021 attttccacc cttataaaag gtccgcttgc gggccttttt tcttagcttt tattccgact
    34081 tgttccgtag tgaacatgct gccacactaa caattctctg ataaggagcc ggtatgttct
    34141 taattaacgg tcataagcag gaatcgctgg cagtaagcga tcgggcaacg cagtttggtg
    34201 atggttgttt taccaccgcc agagttatcg acggtaaagt cagtttgtta tcggcgcata
    34261 tccagcgact acaggatgct tgtcagcggt tgatgatttc ctgtgacttc tggcctcagc
    34321 ttgaacaaga gatgaaaacg ctggcagcag aacagcaaaa tggtgtgctg aaagtcgtga
    34381 tcagtcgcgg tagtggcggg cgagggtaca gcacattgaa cagcggaccg gcaacgcgga
    34441 ttctctccgt tacggcttat cctgcacatt acgaccgttt gcgtaacgag gggattacgt
    34501 tggcgctaag cccggtgcgg ctggggcgca atcctcatct tgcaggtatt aaacatctca
    34561 atcgtcttga gcaagtattg attcgctctc atcttgagca gacaaacgct gatgaggcgc
    34621 tggtccttga cagcgaaggg tgggttacgg aatgctgtgc ggctaatttg ttctggcgga
    34681 agggcaacgt agtttatacg ccgcgactgg atcaggcagg tgttaacggc attatgcgac
    34741 aattctgtat ccgtttgctg gcacaatcct cttatcagct tgtcgaagtg caagcctctc
    34801 tggaagagtc gttgcaggca gatgagatgg ttatttgtaa tgcgttaatg ccagtgatgc
    34861 ccgtatgtgc ctgtggcgat gtctcctttt cgtcagcaac gttatatgaa tatttagccc
    34921 cactttgtga gcgcccgaat tagtcatgaa aaaagtgtta ttgataatct tgttattgct
    34981 ggtggtactg ggtatcgccg ctggtgtggg cgtctggaag gttcgccatc ttgccgacag
    35041 caaattgctt atcaaagaag agacgatatt taccctgaag ccagggaccg gacgtctggc
    35101 gctcggtgaa cagctttatg ccgataagat catcaatcgt ccacgggttt ttcaatggct
    35161 gctgcgtatc gaaccggatc tttctcactt taaagccggg acttaccgct ttacaccgca
    35221 gatgaccgtg cgcgagatgc tgaaattgct ggaaagcggt aaagaagcac agttccctct
    35281 gcgactggta gaagggatgc gtctgagcga ttacctcaag caattgcgtg aggccccgta
    35341 tatcaagcat acgctgagcg atgataagta cgccaccgta gcgcaggcac ttgaactgga
    35401 aaacccggag tggattgaag gttggttctg gccagacacc tggatgtata ccgccaatac
    35461 caccgatgtc gcgttactca agcgagcgca caagaaaatg gtgaaagcgg tcgatagcgc
    35521 ctgggaaggg cgtgcggacg gtctgcctta taaagataaa aaccagttgg tgacgatggc
    35581 atcaattatc gaaaaagaaa ccgccgttgc cagtgaacgc gataaggttg cctcagtatt
    35641 tatcaaccgt ttacgcattg gtatgcgcct gcagaccgac ccgaccgtga tttacgggat
    35701 gggagagcgt tataatggca aactttctcg tgcagacctg gaaacgccga cagcgtataa
    35761 cacctatacc attaccggtc tgccgccagg tgcgatagcg acgccggggg cggattcgct
    35821 gaaggctgct gcgcatccgg caaaaacgcc gtatctctat tttgtggccg atggtaaagg
    35881 tggtcacacg tttaatacca atcttgccag tcataacaag tctgtgcagg attatctgaa
    35941 agtgcttaag gaaaaaaatg cgcagtaagt atatcgtcat tgaggggctg gaaggcgcag
    36001 gcaaaactac cgcgcgtaat gtggtggttg agacgctcga gcaactgggt atccgcgaca
    36061 tggttttcac tcgggaacct ggcggtacgc aacttgccga aaagttaaga agcctggtgc
    36121 tggatatcaa atcggtaggc gatgaagtca ttaccgataa agccgaagtt ctgatgtttt
    36181 atgccgcgcg cgttcaactg gtagaaacgg tcatcaaacc agctctggct aacggcacct
    36241 gggtgattgg cgatcgccac gatctctcca ctcaggcgta tcagggcggc ggacgtggta
    36301 ttgaccaaca tatgctggca acactgcgtg atgctgttct cggggatttt cgccccgact
    36361 taacgctcta tctcgatgtt accccggaag ttggcttaaa acgcgcgcgt gcgcgcggcg
    36421 agctggatcg tattgagcaa gaatctttcg atttctttaa tcgcacccgc gcccgctatc
    36481 tggaactggc agcacaagat aaaagcattc ataccattga tgccacccag ccgctggagg
    36541 ccgtgatgga tgcaatccgc actaccgtga cccactgggt gaaggagttg gacgcatgag
    36601 atggtatcca tggttacgac ctgatttcga aaaactggta gccagctatc aggccggaag
    36661 aggtcaccat gcgctactca ttcaggcgtt accgggcatg ggcgatgatg ctttaatcta
    36721 cgccctgagc cgttatttac tctgccaaca accgcagggc cacaaaagtt gcggtcactg
    36781 tcgtggatgt cagttgatgc aggctggcac gcatcccgat tactacaccc tggctcccga
    36841 aaaaggaaaa aatacgctgg gcgttgatgc ggtacgtgag gtcaccgaaa agctgaatga
    36901 gcacgcacgc ttaggtggtg cgaaagtcgt ttgggtaacc gatgctgcct tactaaccga
    36961 cgccgcggct aacgcattgc tgaaaacgct tgaagagcca ccagcagaaa cctggttttt
    37021 cctggctacc cgcgagcctg aacgtttact ggcaacatta cgtagtcgtt gtcggttaca
    37081 ttaccttgcg ccgccgccgg aacagtacgc cgtgacctgg ctttcacgcg aagtgacaat
    37141 gtcacaggat gcattacttg ccgcattgcg cttaagcgcc ggttcgcctg gcgcggcact
    37201 ggcgttgttt cagggagata actggcaggc tcgtgaaaca ttgtgtcagg cgttggcata
    37261 tagcgtgcca tcgggcgact ggtattcgct gctagcggcc cttaatcatg aacaagctcc
    37321 ggcgcgttta cactggctgg caacgttgct gatggatgcg ctaaaacgcc atcatggtgc
    37381 tgcgcaggtg accaatgttg atgtgccggg cctggtcgcc gaactggcaa accatctttc
    37441 tccctcgcgc ctgcaggcta tactggggga tgtttgccac attcgtgaac agttaatgtc
    37501 tgttacaggc atcaaccgcg agcttctcat caccgatctt ttactgcgta ttgagcatta
    37561 cctgcaaccg ggcgttgtgc taccggttcc tcatctttaa gagagacatc atgtttttag
    37621 tcgactcaca ctgccatctc gatggtctgg attatgaatc tttgcataag gacgtggatg
    37681 acgttctggc gaaagccgcc gcacgcgatg tgaaattttg tctggcagtc gccacaacat
    37741 taccgggtta tttacatatg cgggatctgg taggcgaacg tgacaacgtc gtattttctt
    37801 gtggcgtgca tccactcaac cagaatgatc cctacgatgt agaagattta cgccgtctgg
    37861 cggcagaaga gggtgttgta gcgctgggtg aaaccgggct ggattattat tacacgccgg
    37921 aaactaaagt acgtcagcaa gagtccttca tccatcatat ccagattggt cgtgaactga
    37981 acaagccggt tatcgtccat acccgtgacg cccgtgccga tacgctggca attctgcgcg
    38041 aagaaaaagt gacggattgc ggtggcgtac tacactgttt tacagaggac agagaaacgg
    38101 cgggtaaatt actggatctc ggattttaca tctccttttc cggcattgtg accttccgta
    38161 atgcggagca actgcgcgat gctgcgcgtt atgtccccct ggatcggtta ctggtggaaa
    38221 ctgactcacc ttaccttgcg ccggtaccgc atcgaggaaa agagaatcaa cctgcgatgg
    38281 ttcgtgacgt tgcagaatac atggctgtgt tgaaaggtgt tgccgttgaa gaactggcgc
    38341 aggtaaccac cgataacttc gcccgtctgt ttcacatcga cgcttcccgc cttcaatcca
    38401 tccgttgaat gagttttttt aaagctcgta attaatggct aaaacgagta aagttcaccg
    38461 ccgaaaattg ggcggtgaat aaccacgttt gaaatattgt gacatatgtt ttgtcaaaat
    38521 gtgcaacttc tccaatgatc tgaagttgaa acgtgatagc cgtcaaacaa attggcactg
    38581 aattatttta ctctgtgtaa taaataaagg gcgcttagat gccctgtaca cggcgaggct
    38641 ctcccccctt gccacgcgtg agaacgtaaa aaaagcaccc atactcagga gcactctcaa
    38701 ttatgtttaa gaatgcattt gctaacctgc aaaaggtcgg taaatcgctg atgctgccgg
    38761 tatccgtact gcctatcgca ggtattctgc tgggcgtcgg ttccgcgaat ttcagctggc
    38821 tgcccgccgt tgtatcgcat gttatggcag aagcaggcgg ttccgtcttt gcaaacatgc
    38881 cactgatttt tgcgatcggt gtcgccctcg gctttaccaa taacgatggc gtatccgcgc
    38941 tggccgcagt tgttgcctat ggcatcatgg ttaaaaccat ggccgtggtt gcgccactgg
    39001 tactgcattt acctgctgaa gaaatcgcct ctaaacacct ggcggatact ggcgtactcg
    39061 gagggattat ctccggtgcg atcgcagcgt acatgtttaa ccgtttctac cgtattaagc
    39121 tgcctgagta tcttggcttc tttgccggta aacgctttgt gccgatcatt tctggcctgg
    39181 ctgccatctt tactggcgtt gtgctgtcct tcatttggcc gccgattggt tctgcaatcc
    39241 agaccttctc tcagtgggct gcttaccaga acccggtagt tgcgtttggc atttacggtt
    39301 tcatcgaacg ttgcctggta ccgtttggtc tgcaccacat ctggaacgta cctttccaga
    39361 tgcagattgg tgaatacacc aacgcagcag gtcaggtttt ccacggcgac attccgcgtt
    39421 atatggcggg tgacccgact gcgggtaaac tgtctggtgg cttcctgttc aaaatgtacg
    39481 gtctgccagc tgccgcaatt gctatctggc actctgctaa accagaaaac cgcgcgaaag
    39541 tgggcggtat tatgatctcc gcggcgctga cctcgttcct gaccggtatc accgagccga
    39601 tcgagttctc cttcatgttc gttgcgccga tcctgtacat catccacgcg attctggcag
    39661 gcctggcatt cccaatctgt attcttctgg ggatgcgtga cggtacgtcg ttctcgcacg
    39721 gtctgatcga cttcatcgtt ctgtctggta acagcagcaa actgtggctg ttcccgatcg
    39781 tcggtatcgg ttatgcgatt gtttactaca ccatcttccg cgtgctgatt aaagcactgg
    39841 atctgaaaac gccgggtcgt gaagacgcga ctgaagatgc aaaagcgaca ggtaccagcg
    39901 aaatggcacc ggctctggtt gctgcatttg gtggtaaaga aaacattact aacctcgacg
    39961 catgtattac ccgtctgcgc gtcagcgttg ctgatgtgtc taaagtggat caggccggcc
    40021 tgaagaaact gggcgcagcg ggcgtagtgg ttgctggttc tggtgttcag gcgattttcg
    40081 gtactaaatc cgataacctg aaaaccgaga tggatgagta catccgtaac cactaatccg
    40141 taagacgttg gggagactaa ggcagccaga tggctgcctt ttttacaggt gttattcaga
    40201 attgatacgt gccggtaatg ctgaaattac gcggtgtgcc gtagacgata gaaccttcca
    40261 cgttggtatc gtaggttttg tcgaacaggt tattgacgtt cccctgtaac gagaagtttt
    40321 tcgtcacctg gtagcgggtg aagagatcca ccagcgcgta gctaccttgc tcggcgcgga
    40381 aggtgccata cggcgtcacg gtgtcggtat acacgcgatt ttgccagtta acaccaccgc
    40441 cgaccgtcaa ctctggcatg acaggcaacc gatagctggt gaacatttta accgtggtgc
    40501 gtggcagatt aggattaacg gcgttccctt cgttatcctc tgcaatatag cgcgttgcgc
    40561 caaatgtcag ctgccagttg tcggtaattg cgccgttgag ttcaaattcc acccctttac
    40621 tgactgtccc atccaccgct ttataggcgg tttcgccgtt gctgccgggg ataggtgtac
    40681 cggtggactg agcgacatta tcctgctcaa tacggaagat ggctaacgtg gtggtcagac
    40741 ggctattcat ccagtccgat ttcagaccca gctcgtagtt gttaccggtg attggagcca
    40801 gatatttgcc tgaactgtca cgatcatttt gcggctggaa aatagaggta tagctggcgt
    40861 aggtcgacca gttgtcattg atgtcaaaca ccagaccagc gtaaggcgtg gtgtggtttt
    40921 tctccatgct gtaagtcagc gtatcaaccc gccagttggt ataacgtgcg ccgaggatca
    40981 gatgcagcgg atcggcaagg gtgacacgag tggcagcata taacgatttc atatgtgtgg
    41041 tatcgtcctg cgccaggctc tgtggtgacc agtcggtttg tgggaaattg ccattaaagt
    41101 tgtagaaact gccaatttca tccgggaaga tgttggccca tgaactgaag taacgattgt
    41161 tttgtttgct gtaactgcca ccaaacatta gattgtgctg acgaccaaac aattcataac
    41221 taccgtcagc gaacaaatcc agcgcatcaa ctttacgttt gccactgttc caaccggtgc
    41281 cgccgacata atcaaagcca ggtccataat tactgtatgg cccaaccagc ataccatccg
    41341 ctttgtttac ataggcatcg acatacatca ttttgctgtc aaattcgact tcagagtggg
    41401 tggcattcag tgtcgcttgc caggtatcag caaactgctg cttcagggtc ataaagacct
    41461 tgttgatctc tttatcgttg tacgcccagt caggtgcggt actgcgtgcg cgatcgtaac
    41521 tgttgctgct gccatcagta ttccagcgcg gtaaaccgcc ccaggtaggg ctattaacat
    41581 caatgcgctg atattcgtaa ccggctgaaa gcgtcgtaag atcgcctaaa tcagcatcga
    41641 caatgcccga gaagaaggtc ttttcactgt tgtagcggtc cagccatgag tcgttattct
    41701 ggtagccgcc gacaattcgc gcgcggattt taccgtcttc ggtgagtggg ctttgtaaat
    41761 ccgccacata ccgttctttg ttccagctac cgtattccgc cgagacatcg cctttaaatt
    41821 cacgactggt cgcgtgtttt cgaaccatat taattgccgc agatggatta cccgtcccgg
    41881 tcatgagtcc tgtcgcgcca cgcactactt ctacgcgttc aaagagtgcc atatcagaaa
    41941 gtgcgtcgcc cagattccag cgcgattcaa aataggtggg gataccatca accatatagt
    42001 tatcgatctg gaatccgcgg gaataataaa gagcacgatc ggaatccgcc tgacttttgc
    42061 tgatccccag cgtgttttcc atcacttcgc ccagcgtttg taactgctga tcttccatcc
    42121 gctgctggct aacaatagtg accgactgag gaatatcacg ttgagtcatc tgcattttgg
    42181 tacccgcaga ggtagacgtt acgctgtaat cattttcgcc atcatctgga gctgtggctg
    42241 aaccctcaac aatcaccgtt tcttcagtgg ctggtgcagc aaaagcggca gaaggtaata
    42301 gtgccagtgc tatgcaaccg gcaagtagtg acggtttggt gatggcttga tattgattat
    42361 ccctgttaaa ttgtgttgaa agcatttgaa atctcttggt ttatgttgtc gtcaggctca
    42421 tgccggagga gggtgatgag cgattatatt tagtgtgcga ataattttgt ttgtaaatgc
    42481 aaatgagaaa tatacgcatt catatttgtc atgtaaacca aacagagaat gtcttttcag
    42541 cgcattcgca ggcagaaatg ggaataatgg cgatatatac ggcagcaaaa cgattttttg
    42601 cttaagaaat cgtgagttaa ggttgaaaga gcaggtttaa ctcgaccata ctctatactc
    42661 gcagtgtggc gcggcgtagc atggcgcaac gcatggctat ttgaaaaagg aaaatgtcgt
    42721 ggcagaagaa actatattca gcaaaattat tcgtcgtgag atcccctccg atatcgtcta
    42781 ccaggatgat ctggtaacgg cgtttcgcga tatttcgccg caagcgccaa cgcatattct
    42841 gatcattccg aatatcctca ttccgactgt gaacgacgtc tcagctgagc atgagcaggc
    42901 gctgggacgc atgatcaccg tagcggcaaa aattgctgag caagaaggta ttgccgaaga
    42961 tggctatcgt ctgatcatga ataccaaccg ccatggcgga caagaggttt accacatcca
    43021 tatgcacttg ttgggtggcc gtccgctggg accaatgctg gcgcataaag gtctgtaacg
    43081 atgagaaaag gatgctttgg gctggtgtct ctggtgttgt tactgctggt gggctgtcgt
    43141 tcacatccgg aaattccggt gaatgatgag caatcgctgg tgatggagtc atctttattg
    43201 gctgcgggca tcagtgcaga aaagcccttc ctttcgacgt ctgatattca accttcagca
    43261 tcctcaacgc tttataacga aaggcaagaa cccgttaccg ttcattatcg tttttactgg
    43321 tatgacgcca gagggctgga gatgcatcct ctggaaaggc cacgcagcgt taccattccc
    43381 gcacattcgg cggtaacgct gtacggcagc gccaattttc tgggggcgca caaagtcaga
    43441 ctttatctat atttgtaagg ggtgaatctt gatgacaaaa atgagtcgct acgccttgat
    43501 taccgcgctg gcgatgtttc tcgccgggtg tgtggggcaa cgtgaacctg caccggtaga
    43561 agaagtgaaa ccagcgccgg aacaaccagc cgagccacaa cagcctgtcc ccacagtgcc
    43621 ctcggtgccg acgatcccgc agcagccagg cccaattgag cacgaagatc aaactgcacc
    43681 gcctgcgccg catattcgcc attatgactg gaatggcgca atgcagccga tggtcagtaa
    43741 gatgcttggg gctgacgggg tgactgcggg tagcgtcctg ctggttgata gcgttaacaa
    43801 ccgtactaac ggttcgctga atgccgcaga agcgaccgaa acgctgcgaa atgcgctggc
    43861 taataacggg aaatttaccc tggtttccgc ccagcaactg tcgatggcga agcaacagtt
    43921 aggtttgtcg ccgcaggaca gtttaggcac ccgtagtaaa gccataggca ttgcccgcaa
    43981 tgtcggcgct cattacgtgc tgtactccag cgcctctggc aacgttaacg ctccgaccct
    44041 acaaatgcag ctgatgctgg tgcagacggg cgaaattatc tggtcaggta aaggtgccgt
    44101 ttcgcagcaa taatcccatc acgcgcgacg aattgctgtc gcgctttttc ccgcagtatc
    44161 atcccgtcac gacgtttaat agtgggctta gtggcgggag ttttctcatt gaacatcagg
    44221 gccagcgttt tgttgtgcgt cagccgcacg atcctgatgc gccgcagtcc gcgttcttgc
    44281 gccagtatcg ggctttatca caactacccg catgcattgc accgaagccg catttatatc
    44341 tccgtgactg gatggtagtc gactatctgc ccggcgcggt aaaaacgtat ttgccggata
    44401 ccaacgaact ggcaggcttg ctgtattatc tacatcaaca accacgtttt ggctggcgaa
    44461 taacgctgtt gccgttactg gaactgtact ggcagcaaag cgatccggcg cggcggacag
    44521 tgggttggct gcgaatgtta aaacgtctgc gcaaagcgcg ggaaccacgg cctttacgct
    44581 taagtccatt gcatatggat gtccacgccg gaaatttagt gcatagcgcg tcagggttaa
    44641 aactcatcga ctgggagtat gccggagatg gtgatatcgc gctggaactg gcggcggtgt
    44701 gggtggaaaa tactgaacag caccggcaat tggtcaatga ctatgccact cgcgcgaaga
    44761 tttatccggc gcaattatgg cgtcaggtca ggcgatggtt tccctggctg ctgatgctca
    44821 aagcagggtg gtttgagtac cgctggcgac aaaccggcga tcaacaattt atcaggctgg
    44881 ccgatgacac ctggcggcag ctattaataa aacaataagg agagcagtgt gggtccagta
    44941 atgttggatg tcgaaggtta cgaactggac gcggaagagc gtgaaatact ggcgcatccg
    45001 ctggtgggag ggctgattct ctttacgcgt aactatcatg atcctgccca gttacgtgaa
    45061 ctggtgcgcc agatccgcgc agcttcgcgc aatcgtctgg tggtggcggt tgatcaggaa
    45121 ggtggacgcg tgcagcgttt tcgtgaaggt tttacccgct tgccagcggc gcaatcattc
    45181 gctgcgctgt caggaatgga agagggtggc aaactggcgc aggaggcagg ttggttgatg
    45241 gccagcgaaa tgatcgctat ggatattgat atcagctttg cgcctgtgct ggatgtcggg
    45301 catatcagcg cggcgattgg cgagcgttct tatcatgccg atccacaaaa agccctggca
    45361 attgccagcc ggtttattga tggtatgcat gaagccggaa tgaaaacgac cgggaaacac
    45421 ttcccaggac acggtgcagt aacggcagac tcacacaaag aaacaccgtg cgatccacgt
    45481 ccacaagcgg agattcgcgc taaagatatg tcggtcttca gttccttaat ccgcgaaaat
    45541 aaactcgacg ccattatgcc tgcgcatgtg atctacagtg atgttgatcc gcgtccggcg
    45601 agcggttctc cctactggct gaaaaccgtt ttgcgtcagg aactgggttt tgacggcgtg
    45661 attttctctg acgatttatc gatggaaggt gccgcgatta tgggcagtta tgccgaacgc
    45721 gggcaggctt cactggatgc gggttgcgat atgatcctgg tctgcaataa tcgtaaaggg
    45781 gccgtcagcg tgttagataa tctgtcaccg atcaaggcag aacgtgttac acgtttgtat
    45841 cataaaggtt cattttcgcg acaggaactg atggactcgg ctcgctggaa agcgatcagc
    45901 acccgtctga atcagttaca tgaacgctgg caggaagaga aagcaggtca ctaaccctgg
    45961 cttatgtgag gaagcgatga ttatctattt acacggtttt gactctaaca gtccgggtaa
    46021 ccacgagaaa gtcttacaat tgcagtttat tgacccggat gtacgcttga taagctacag
    46081 tacgcggcat ccgaaacatg atatgcagca tctgcttaaa gaagtggaca aaatgttgca
    46141 actgaacgtt gacgagcgtc cgctaatttg cggcgttggc ttgggcggat actgggcgga
    46201 acggattggt tttctttgcg acatccgcca ggtgatcttc aaccctaatt tgttccctta
    46261 tgagaacatg gaaggcaaga ttgatcgccc ggaagagtat gccgatattg ccactaagtg
    46321 tgtgaccaac ttccgtgaga agaatcgcga tcgttgcctg gtgattttgt cgcgtaatga
    46381 tgaagcgctt aacagccagc ggacatctga agagttgcat cattattacg agattgtctg
    46441 ggacgaagag cagacgcaca aattcaagaa tatctccccg catttacagc gcattaaagc
    46501 gttcaaaacc ctcgggtaaa tgccctcgtc gcatcaggta accttgccgg tacctgatgc
    46561 gctccgaatt ctgtgggtcg gataaggcgt ccacgccgca tccgacagtc gagcatcaat
    46621 gcctgatgcg cttcttatca ggcctaccga acgccctgca tacacccctc actctatatc
    46681 actctcacaa attcgctcaa ataataaaca ataaactctg ttttttgatc tcacccggta
    46741 aagtcgccta tcttttcagc aacaaaactt gattaacatc aattttggta tgaccaatgc
    46801 accattcatg ttattctcaa tagcgaagaa cattttcatt gctgtaacct gttgtta
//
LOCUS       DAPHKZ010000024        46545 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.024, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000024 DAPHKZ010000000
VERSION     DAPHKZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46545
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.024"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(106..1362)
                     /gene="xapB"
                     /locus_tag="RH288_001440"
     CDS             complement(106..1362)
                     /gene="xapB"
                     /locus_tag="RH288_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine/proton symporter XapB"
                     /protein_id="HDV4030510.1"
                     /translation="MSIAMRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVY
                     SSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVN
                     AMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSL
                     QLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAM
                     MLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLK
                     RFGIKTVMLMSMVAWTLRFGFFAYGDPSTTGFILLLLSMIVYGCAFDFFNISGSVFVE
                     QEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWQTIWLVFAGYAL
                     FLAVIFFFGFKYNHDPEKIKHRAVTH"
     gene            complement(1422..2255)
                     /gene="xapA"
                     /locus_tag="RH288_001441"
     CDS             complement(1422..2255)
                     /gene="xapA"
                     /locus_tag="RH288_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine phosphorylase"
                     /protein_id="HDV4030511.1"
                     /translation="MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIE
                     NAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIR
                     TFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL
                     ANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV
                     PEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI
                     A"
     gene            2504..3268
                     /locus_tag="RH288_001442"
     CDS             2504..3268
                     /locus_tag="RH288_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030512.1"
                     /translation="MKKHLLTLTLSSILAIPVVSHAEFKGGFADIGVHYLDWTSRTTE
                     KSSTKSHKDDFGYLEFEGGANFSWGEMYGFFDWENFYNGRHNKPGSEQRYTFKNTNRI
                     YLGDTGFNLYLHAYGTYGSANRVNFHDDMFLYGIGYNFTGSGWWFKPFFAKRYTDQTY
                     YTGDNGYVAGWVAGYNFMLGSEKFTLTNWNEYEFDRDATYAAGNGGKEGLNGAVALWW
                     NATSHITTGIQYRYADDKLGEDFYQDAIIYSIKFNF"
     gene            complement(3307..4233)
                     /locus_tag="RH288_001443"
     CDS             complement(3307..4233)
                     /locus_tag="RH288_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4030513.1"
                     /translation="MNYSLKQLKVFVTVAQEKSFSRAGERIGLSQSAVSHSVKELENH
                     TGVRLLDRTTREVVLTDAGQQLALRLERLLDELNSTLRDTGRMGQQLSGKVRVAASQT
                     ISAHLIPQCIAESHRRYPDIQFVLHDRPQQWVMESIRQGDVDFGIVIDPGPVGDLQCE
                     AILSEPFFLLCHRDSALAVEDYVPWQALQGAKLVLQDYASGSRPLIDAALARNGIQAN
                     IVQEIGHPATLFPMVAAGIGISILPALALPLPEGSPLVVKRITPVVERQLMLVRRKNR
                     SLSTAAEALWDVVRDQGNTLMAGREGDPLYQI"
     gene            4323..5321
                     /locus_tag="RH288_001444"
     CDS             4323..5321
                     /locus_tag="RH288_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HDV4030514.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIAL
                     LFFMHGAKLSREAIIAGGGHWRLHLWVMCSTFVLFPILGVLFAWWKPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGS
                     LEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVN
                     GIWHKVGWGSLLFIVVVSCVLLAIVIVVNVFMARRLSFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKRQTEQLQAQQESSADKA"
     gene            complement(5318..5536)
                     /locus_tag="RH288_001445"
     CDS             complement(5318..5536)
                     /locus_tag="RH288_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HDV4030515.1"
                     /translation="MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAG
                     KLGELMQITLLIKTEGLTQLVQPLKRPL"
     gene            complement(5538..7553)
                     /gene="ligA"
                     /locus_tag="RH288_001446"
     CDS             complement(5538..7553)
                     /gene="ligA"
                     /locus_tag="RH288_001446"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDV4030516.1"
                     /translation="MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRE
                     LETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEED
                     RPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAE
                     ESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVEL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS"
     gene            complement(7624..8610)
                     /gene="zipA"
                     /locus_tag="RH288_001447"
     CDS             complement(7624..8610)
                     /gene="zipA"
                     /locus_tag="RH288_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HDV4030517.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPR
                     QPVQQPPEAQVPPQHAPHPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPA
                     QQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQ
                     AGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYG
                     DELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA"
     gene            8840..9601
                     /gene="cysZ"
                     /locus_tag="RH288_001448"
     CDS             8840..9601
                     /gene="cysZ"
                     /locus_tag="RH288_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HDV4030518.1"
                     /translation="MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMG
                     GAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAP
                     FNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIP
                     GIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSL
                     FTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR"
     gene            9786..10757
                     /gene="cysK"
                     /locus_tag="RH288_001449"
     CDS             9786..10757
                     /gene="cysK"
                     /locus_tag="RH288_001449"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDV4030519.1"
                     /translation="MSKIFEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFIAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPANLDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            11141..11398
                     /gene="ptsH"
                     /locus_tag="RH288_001450"
     CDS             11141..11398
                     /gene="ptsH"
                     /locus_tag="RH288_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HDV4030520.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            11443..13170
                     /gene="ptsI"
                     /locus_tag="RH288_001451"
     CDS             11443..13170
                     /gene="ptsI"
                     /locus_tag="RH288_001451"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HDV4030521.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFL
                     SGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
                     ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYL
                     ILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAIRIAMDRREILRDQLRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            13211..13720
                     /gene="crr"
                     /locus_tag="RH288_001452"
     CDS             13211..13720
                     /gene="crr"
                     /locus_tag="RH288_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDV4030522.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(13763..14614)
                     /gene="pdxK"
                     /locus_tag="RH288_001453"
                     /gene_synonym="thiJ"
     CDS             complement(13763..14614)
                     /gene="pdxK"
                     /locus_tag="RH288_001453"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HDV4030523.1"
                     /translation="MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGL
                     NVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQ
                     IKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
                     FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVVTSASGNEENQEMQVVVVTADSVNV
                     ISHSRVKTDLKGTGDLFCAQLISGLLKGKALTDAVHRAGLRVLEVMRYTQQHESDELI
                     LPPLAEA"
     gene            14719..15093
                     /locus_tag="RH288_001454"
     CDS             14719..15093
                     /locus_tag="RH288_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HDV4030524.1"
                     /translation="MKKIICLVITLLMTLPVYAKLTAHEEARINAMLEGLAQKKDLIF
                     VRNGDEHTCYEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKIPGKSDE
                     NAQPFLHALIAQTDKTVPAEGN"
     gene            15126..15860
                     /locus_tag="RH288_001455"
     CDS             15126..15860
                     /locus_tag="RH288_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR domain-containing protein"
                     /protein_id="HDV4030525.1"
                     /translation="MKKRFIYHDEKSNKFWWIDYEGDSLAVNYGKVGSIGKFQTKEFD
                     NEEQCLKEASKLIAAKMKKGYQEDPKFNFMDRYYFDDEEIGLHVKTSHPNFQCHFTDP
                     LYMCCWDEESPFGSDEGADALNVLENSLRKEPDLDCADFPQMLIETMWGMKYIAMDSI
                     LEEDVRAQLLVDEMSTIQSNMITYATAFGQIKVMGKISHKLKKMGLNALARHQLTAKI
                     LQWGDGQDSPILQKMIDDLTAFPHEN"
     gene            complement(16049..16960)
                     /gene="cysM"
                     /locus_tag="RH288_001456"
     CDS             complement(16049..16960)
                     /gene="cysM"
                     /locus_tag="RH288_001456"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="HDV4030526.1"
                     /translation="MSTLEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
                     QTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPTEYLP
                     GIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPDAVVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(17094..18191)
                     /gene="cysA"
                     /locus_tag="RH288_001457"
     CDS             complement(17094..18191)
                     /gene="cysA"
                     /locus_tag="RH288_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HDV4030527.1"
                     /translation="MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPDQVWREPATRFVLEFMGEVNRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYNEPLTVVMHGDDAPQRGE
                     RLFVGLQHARLYNGDERIETRDEELALAQSA"
     gene            complement(18181..19056)
                     /gene="cysW"
                     /locus_tag="RH288_001458"
     CDS             complement(18181..19056)
                     /gene="cysW"
                     /locus_tag="RH288_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HDV4030528.1"
                     /translation="MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEEHHEH"
     gene            complement(19056..19889)
                     /gene="cysT"
                     /locus_tag="RH288_001459"
     CDS             complement(19056..19889)
                     /gene="cysT"
                     /locus_tag="RH288_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HDV4030529.1"
                     /translation="MFAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLAQMSW
                     AQYWEVITNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAETLGATRWQSFCKVVLPELSPALVAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            complement(19889..20905)
                     /gene="cysP"
                     /locus_tag="RH288_001460"
     CDS             complement(19889..20905)
                     /gene="cysP"
                     /locus_tag="RH288_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HDV4030530.1"
                     /translation="MAVNLLKKNSLALVASLLLAGHVQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADKADGGDKGKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQA
                     QTIITDYYYRVNNPEVMDKLKDKFPQTELFRVEDKFGSWPEVMKTHFTSGGELDKLLA
                     AGRN"
     gene            complement(21209..22000)
                     /gene="ucpA"
                     /locus_tag="RH288_001461"
     CDS             complement(21209..22000)
                     /gene="ucpA"
                     /locus_tag="RH288_001461"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416921.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HDV4030531.1"
                     /translation="MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEK
                     LADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMS
                     DDDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPM
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI"
     gene            complement(22129..22986)
                     /gene="murR"
                     /locus_tag="RH288_001462"
     CDS             complement(22129..22986)
                     /gene="murR"
                     /locus_tag="RH288_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MurR"
                     /protein_id="HDV4030532.1"
                     /translation="MLYLTKISNAGSEFTENEQKIADFLQANVSELQSVSSRQMAKQL
                     GISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIA
                     RKLNREKELALEQTCALLDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
                     GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSL
                     TDSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQR
                     SSELTQRLK"
     gene            23150..24046
                     /gene="murQ"
                     /locus_tag="RH288_001463"
     CDS             23150..24046
                     /gene="murQ"
                     /locus_tag="RH288_001463"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDV4030533.1"
                     /translation="MQFEKMITEGSNTASAEIDRVSTLEMCRIINDEDKTVPLAVERV
                     LPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGG
                     EYAIQHAVEGAEDSREGGVNDLKNINLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
                     TVGISCNPGSAVSTTAEFAITPIVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGK
                     VFGNLMVDVVATNEKLHVRQVNIVKNATGCSAEQAEAALIACERNCKTAIVMVLKNLD
                     AAEAKKRLDQHGGFIRQVLDKE"
     gene            24050..25474
                     /gene="murP"
                     /locus_tag="RH288_001464"
     CDS             24050..25474
                     /gene="murP"
                     /locus_tag="RH288_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylmuramic acid transporter subunit
                     IIBC"
                     /protein_id="HDV4030534.1"
                     /translation="MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVD
                     PNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQL
                     KAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
                     FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDF
                     FGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIM
                     PLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNS
                     LFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMK
                     PFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAG
                     GILVAWVCGFIFTTLFGCRNVNLD"
     gene            25479..26783
                     /gene="pbp4b"
                     /locus_tag="RH288_001465"
     CDS             25479..26783
                     /gene="pbp4b"
                     /locus_tag="RH288_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin binding protein PBP4B"
                     /protein_id="HDV4030535.1"
                     /translation="MKRTMLYLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMD
                     RWISQQVDVGYPSVNLLIIKDNQIVYRKAWGAAKKYDGSVLMEQPVKATTGTLYDLAS
                     NTKMYATNFALQKLMSEGKLHPDDRIAKYIPGFADSPNDTIKGKNTLRISDLLHHSGG
                     FPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESV
                     TGQPLDRYVEESIYRPLGLTHTVFNPLLKGFKPQQIAATELNGNTRDGVIHFPNIRTS
                     TLWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGYGDVQLFNAETVKMF
                     TTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMTIVML
                     SNKPHSPVADPQKNPNMFESGQLPIATYGWVVDQVYAALKQK"
     gene            complement(27023..27922)
                     /gene="yfeX"
                     /locus_tag="RH288_001466"
     CDS             complement(27023..27922)
                     /gene="yfeX"
                     /locus_tag="RH288_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311329.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HDV4030536.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATF
                     EAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDKLMAL"
     gene            complement(28018..28593)
                     /locus_tag="RH288_001467"
     CDS             complement(28018..28593)
                     /locus_tag="RH288_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HDV4030537.1"
                     /translation="MKSLRLMLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQ
                     GVGELTASTPLQEQAIADALDGDYRLRSGMKTANGNVVRFFEVMKGDNVAMVINGDQG
                     TISRIDVLDSDIPADTGVKIGTPFSDLYSKAFGNCQKADGDDNRAVECKAEGSQHISY
                     QFSGEWRGPEGLMPSDDTLKNWKVSKIIWRR"
     gene            complement(28654..29103)
                     /locus_tag="RH288_001468"
     CDS             complement(28654..29103)
                     /locus_tag="RH288_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HDV4030538.1"
                     /translation="MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASR
                     EQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRATFPRTWRVLYFLLLLAQVVL
                     LCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFNEVKE"
     gene            complement(29090..29515)
                     /locus_tag="RH288_001469"
     CDS             complement(29090..29515)
                     /locus_tag="RH288_001469"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HDV4030539.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSL
                     FLVAEVNGDVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY"
     gene            29729..30598
                     /gene="amiA"
                     /locus_tag="RH288_001470"
     CDS             29729..30598
                     /gene="amiA"
                     /locus_tag="RH288_001470"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HDV4030540.1"
                     /translation="MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDELLKTSNG
                     HSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDA
                     RLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKL
                     HSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYF
                     HWFDNQKAHSKKR"
     gene            30602..31501
                     /gene="hemF"
                     /locus_tag="RH288_001471"
     CDS             30602..31501
                     /gene="hemF"
                     /locus_tag="RH288_001471"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HDV4030541.1"
                     /translation="MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGG
                     RSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYV
                     PTSHANVRFFIAEKPGADPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVY
                     PRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDRCFAFMQAVGKGYTDAYLPIVE
                     RRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DYQPKDGSPEAALSEFIKVRDWV"
     gene            complement(31507..32559)
                     /gene="eutR"
                     /locus_tag="RH288_001472"
     CDS             complement(31507..32559)
                     /gene="eutR"
                     /locus_tag="RH288_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HDV4030542.1"
                     /translation="MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHA
                     LTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGEQGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
                     RVLHMLRNQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMG
                     AMLEEAQPMVTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSMTVKDAAMQWGFWHLGQFATDYQQLF
                     SEKPSLTLHQRMREWG"
     gene            complement(32605..33105)
                     /gene="eutK"
                     /locus_tag="RH288_001473"
     CDS             complement(32605..33105)
                     /gene="eutK"
                     /locus_tag="RH288_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416933.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HDV4030543.1"
                     /translation="MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTL
                     VVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVREPD
                     APVIVAESADELLALLTSVRQGMTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
                     YRLKPH"
     gene            complement(33118..33777)
                     /gene="eutL"
                     /locus_tag="RH288_001474"
     CDS             complement(33118..33777)
                     /gene="eutL"
                     /locus_tag="RH288_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDV4030544.1"
                     /translation="MPALDLIRPSVTAMRVIASVNAEFARELKLPPHIRSLGLISADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MIAHIENGAAFQWANDAQDTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
                     GIDAALKSADVQLATYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQR
                     A"
     gene            complement(33787..34674)
                     /gene="eutC"
                     /locus_tag="RH288_001475"
     CDS             complement(33787..34674)
                     /gene="eutC"
                     /locus_tag="RH288_001475"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit beta"
                     /protein_id="HDV4030545.1"
                     /translation="MDQKQIEEIVRSVMASMGQTAPAPSEAKCATTNCAAPVTSESCA
                     LDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRS
                     KDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
                     VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILG
                     AKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVI
                     VDLAKRMLEQKASGINMTR"
     gene            complement(34695..36056)
                     /gene="eutB"
                     /locus_tag="RH288_001476"
     CDS             complement(34695..36056)
                     /gene="eutB"
                     /locus_tag="RH288_001476"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HDV4030546.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
                     LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNI
                     PTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPS
                     LFF"
     gene            complement(36068..37471)
                     /gene="eutA"
                     /locus_tag="RH288_001477"
     CDS             complement(36068..37471)
                     /gene="eutA"
                     /locus_tag="RH288_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDV4030547.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKR
                     EISWQSPVFFTPVDKQGGLKEAELKSLILEQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMALSQSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
                     ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGAGTDARSLTGAQL
                     VQVTRRMAALIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADP
                     FCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQL
                     PLRNLPVAIPIDETDLVGAWQQALIQLDLDPKTDAYVLALPASLPVRYAAVLTVINAL
                     VDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            complement(37468..38694)
                     /gene="eutH"
                     /locus_tag="RH288_001478"
     CDS             complement(37468..38694)
                     /gene="eutH"
                     /locus_tag="RH288_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDV4030548.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPE
                     KMINGFQIFAKFLVALITLGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKEDATATKTEAEAQS"
     gene            complement(38911..40098)
                     /gene="eutG"
                     /locus_tag="RH288_001479"
     CDS             complement(38911..40098)
                     /gene="eutG"
                     /locus_tag="RH288_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HDV4030549.1"
                     /translation="MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQA
                     QTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQL
                     RESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQIGRALRTKKSDDRD
                     AINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAALEDICLRSNPRTASLEQIVGLYA
                     AAQ"
     gene            complement(40088..40924)
                     /gene="eutJ"
                     /locus_tag="RH288_001480"
     CDS             complement(40088..40924)
                     /gene="eutJ"
                     /locus_tag="RH288_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HDV4030550.1"
                     /translation="MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSM
                     VVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGLRFSHAATSFPP
                     GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
                     YSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGEEIWPAVKPVYEKMADIVARHIE
                     GQGITDLWLAGGSCLQPGVAELFRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLY
                     AK"
     gene            complement(40935..42338)
                     /locus_tag="RH288_001481"
     CDS             complement(40935..42338)
                     /locus_tag="RH288_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HDV4030551.1"
                     /translation="MNQQDIEQVVKAVLLKMQSSDTPSAAVHEMGVFASLDDAVAAAK
                     VAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
                     HPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGE
                     AVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGTVSRDWVGRDAAKIA
                     AAIGLNVPQETRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHH
                     TAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            complement(42350..42637)
                     /gene="eutN"
                     /locus_tag="RH288_001482"
     CDS             complement(42350..42637)
                     /gene="eutN"
                     /locus_tag="RH288_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HDV4030552.1"
                     /translation="MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPHGNPDGQCAVAI
                     DNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIGIVDEVVSGGQVIFHK"
     gene            complement(42744..43037)
                     /gene="eutM"
                     /locus_tag="RH288_001483"
     CDS             complement(42744..43037)
                     /gene="eutM"
                     /locus_tag="RH288_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDV4030553.1"
                     /translation="MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAM
                     VRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPIGLKGDSSNL"
     gene            complement(43076..44092)
                     /gene="pta"
                     /locus_tag="RH288_001484"
     CDS             complement(43076..44092)
                     /gene="pta"
                     /locus_tag="RH288_001484"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDV4030554.1"
                     /translation="MIIERCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPIL
                     VANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFAHRWLARAGEKTPPDALEKLTD
                     PLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
                     ALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANV
                     QQATEIVRERAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQ
                     TLVE"
     gene            complement(44089..44892)
                     /gene="eutT"
                     /locus_tag="RH288_001485"
     CDS             complement(44089..44892)
                     /gene="eutT"
                     /locus_tag="RH288_001485"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HDV4030555.1"
                     /translation="MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLR
                     IKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHPQACCELCRQPVAKKPDTLTHLSAEKM
                     VAKSDPRLGFRAVLDSTIALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLGC
                     QAIVGLSDEDLHRLSHQPLRYLDHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVF
                     ITRSFEVLRPDILQALNRLSSTVYVMMILSVTKQPLTVKQIQQRLGETQ"
     gene            complement(44889..45590)
                     /gene="eutQ"
                     /locus_tag="RH288_001486"
     CDS             complement(44889..45590)
                     /gene="eutQ"
                     /locus_tag="RH288_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HDV4030556.1"
                     /translation="MKKLITANDIREAHARGEQAMSVVLRASIITPEAREVADLLGFT
                     ITECDESIPVTASVPASVPADKTESQRIRETIIAQLPEGQFTESLVAQLMEKVMKEKQ
                     SLEQGAMQPSFKSVTGKGGIKVIDGSSVKFGRFDGAEPHCVGLTDLVTGDDGSSMAAG
                     FMQWENAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTTSS
                     VKFLYVAWPANWQSL"
     gene            complement(45565..46044)
                     /gene="eutP"
                     /locus_tag="RH288_001487"
     CDS             complement(45565..46044)
                     /gene="eutP"
                     /locus_tag="RH288_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HDV4030557.1"
                     /translation="MKRIAFVGSVGAGKTTLFNALQGNYTLARKTQAVEFNDKGDIDT
                     PGEYFNHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSKRQIAVISKTD
                     MPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE"
     gene            complement(46057..46392)
                     /gene="eutS"
                     /locus_tag="RH288_001488"
     CDS             complement(46057..46392)
                     /gene="eutS"
                     /locus_tag="RH288_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HDV4030558.1"
                     /translation="MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIYGSVGAVEEALSQTVSGLGRLLN
                     YTLCEMTKS"
BASE COUNT        10967 a        12903 c        11820 g        10855 t
ORIGIN      
        1 aacaaagcac caataccaaa accaacgccg gaagaaaata aaatatcttt cactaattaa
       61 cctttatcat aaaagcagct ctgaagagca gagccgcgaa tccttttaat gagtcaccgc
      121 tcgatgcttt atcttttcag ggtcatgatt atatttaaac ccaaagaaaa atatcactgc
      181 gagaaaaaga gcatatcctg caaacaccag ccagatagtt tgccagtctt ttacgccatc
      241 caccgaaaag taatctactg ccatgccact cagaatcgag ccaacccatg cgccgacacc
      301 atttaccatg gtcataaaga gcccctgcgc gctggcacga atgctggaat caacttcctg
      361 ttcgacaaat accgaaccag aaatattgaa gaaatcgaat gcacagccat aaacaatcat
      421 cgacagcagc agcaaaataa atccggttgt tgacggatcg ccataggcga agaagccaaa
      481 gcgcagcgtc caggccacca tactcatcag catgacggtt ttaatgccaa atcgctttaa
      541 aaagaatggg atagtcagta taaagcccac ttctgccatc tgtgaaactg acagtaaaat
      601 ggagggatat ttcaccacaa aactgtcagc aaactccggg ttacgggcga aatcatgtag
      661 gaacggatta ccaaaaacgt tggtaatttg cagtaccgca cccagcatca tggcaaagag
      721 gaaaaagatg gccatgcgtg gatttttaaa cagcacgaag gcatccagac ccagcttgct
      781 ggcaagcgat gtggtcgctt ttttctccgc aaccggaatc ttcggcaaag tcagcgcata
      841 agccgacagc agcaatgacg caccggacgc gatatacagc tgcagactac tcaattccag
      901 atgcagcagg cttactgccc acatcgcgac aatgaacccc accgtaccaa aaacgcgaat
      961 gggcgggaaa gcggtcaccg ggtcaagccc tgcctgggca agacaggaat aagagacgct
     1021 gttcgataac gcaatagtcg gcataaacgc catcgcattg actaacatca cccaaaacat
     1081 catatccgga tcagttacgg atgccgcata aaaaagtacg cccgcacaca ccaggtgaca
     1141 cagcatgtat gcacgttctg cgcgcagcca tttgtctgcg atgatcccca ttataccagg
     1201 cataataatc gcggcgatcc ctttggaact gtaaaccatg ccaacattag cgccggtgaa
     1261 atgaagagta ttaatcatgt aagagccgag ggtaaccagc cagctccccc agataaaata
     1321 ttgcaaaaag gacattacct ttaagcgcat cgcgatgctc ataatcgttt ccttgtcgca
     1381 tcatttggcc tcacccgcga ggccgtttct tattgttttt ctcaggcaat tttgcgcaga
     1441 aagccacaaa taaggttgat gaagttctgc ttagagagct ccgcagccgc cagcgtttgc
     1501 gcatgtgaca atttcacatc gcttaaacct tccgccatat tggtaatcgc agagaccgca
     1561 acgactttaa ggtcgcaatg gcgagctgaa ataacctcag gcaccacaga cataccaaca
     1621 acatccccac caataatttg catcatgcga atttccgccg cagtctcgaa attcggcccc
     1681 ggatacgaga cgaacacgcc ctccgtcaga gggaaaccct cttctttcgc cactttttgt
     1741 aacagtgcgc ggtattccgc atcgtaggca tttgccagtg agaagaagcg ctctccaaaa
     1801 cgatcatcgt taagacccac catcggcgta ccgggcatgg tgttgatatg atctttcaat
     1861 gcgaccaggc tgcctgcccc cacttccgga cgcagcgagc ctgccgcatt ggtgcagaac
     1921 agtagctcgc agcccagcag cttaaaggta cgaattgcgt cagtcataat ggtcattcca
     1981 cgaccttcgt agaaatgtcc gcgacctttc atacatacca ccggtacgcc ctggagatgg
     2041 cccagcacta actcccccgc atgaccatgt accgtactta ccgggaagcc cggcagcttt
     2101 tcgtaggaaa ttgcgacagc gttctcaatc tgatcggcca gcgcgccgag cccggaacct
     2161 aaaataaagg ccactcgtgg cgtgaaatca ggtttataag tcttgataat atctatgcaa
     2221 aacagcgggt tatgagaaaa ttgaacctga gacatacata tcctttttct gtagggtgga
     2281 atctaacgcc tttttatagc gaggttgtcc cggctcttac caatacactt ttctcacgca
     2341 ttcaatagcg attcgatatc gatggattta tatcttttct ctattaatcc acggtaaaaa
     2401 ctgtattggc gatattaatt cctttgcatt aacaatatgt cgtttttagc aaaccacttt
     2461 attaagcaat ctactaataa cgatcggcat agggaattat gctatgaaaa aacatctttt
     2521 aactctgaca ctttcctcta tattagcgat acctgttgta tctcatgcag aatttaaagg
     2581 cggttttgca gatatcggcg tgcattatct ggactggacc agccggacta ccgaaaaatc
     2641 gtcgaccaaa tcacacaaag atgattttgg ttatcttgaa tttgaaggtg gcgctaactt
     2701 tagttgggga gaaatgtacg ggttcttcga ctgggaaaac ttctataacg gtcgccataa
     2761 taaaccaggt agcgagcagc gttatacctt taaaaatacc aaccgtattt acctgggtga
     2821 caccggattt aatctctact tgcatgcgta tggcacctac ggttctgcga atcgcgtgaa
     2881 tttccacgac gatatgttcc tgtacggtat cggctacaat ttcaccggca gcggttggtg
     2941 gttcaaaccg ttctttgcta agcgttatac agatcaaacc tattacactg gcgacaacgg
     3001 ctatgtcgcc ggctgggttg caggttacaa ctttatgctg ggcagcgaga aattcactct
     3061 taccaactgg aacgagtacg agtttgaccg tgacgctacc tatgcagcgg gtaatggcgg
     3121 taaagaaggg ctgaatggcg cagttgcact gtggtggaat gcaacatcac acattactac
     3181 ggggattcag tatcgatatg cggatgacaa actgggcgaa gatttttacc aggatgcgat
     3241 aatctactcc atcaaattta acttctgatt gattactgcc ggggctcccg gcagtatgaa
     3301 ttcactctat atctgataca acggatcccc ttcccgccca gccattagcg tattgccctg
     3361 gtctcgtacc acgtcccata aagcttcagc ggcggtggaa agtgaacggt tcttcctgcg
     3421 caccagcatc aactggcgtt caacaaccgg cgtaatgcgc tttaccacca gtgggctacc
     3481 ttcaggcaat ggtagcgcca gtgcgggaag aatactgatg ccgatgcctg cggctaccat
     3541 cgggaacagc gtcgccggat gtccaatctc ctgcacaata ttcgcctgaa taccattgcg
     3601 cgccagcgct gcgtcaatca gcggtcggct gcctgacgcg taatcctgca acaccaattt
     3661 cgctccctgt aatgcctgcc agggtacata atcttccacg gccaaagcgc tatcgcgatg
     3721 gcaaagcaga aagaaaggct cggaaagaat cgcttcacat tgcagatcgc ccactgggcc
     3781 tggatcgatg acgatgccaa aatcgacatc tccctggcga atactttcca ttacccactg
     3841 ctgcggacga tcgtgcagga caaactgaat atctggatag cggcgatggc tttcagcaat
     3901 gcattgcgga ataagatgcg cggaaatggt ctggctggca gcgacccgaa cttttccgct
     3961 cagttgttgc cccatacgcc cggtatcgcg caacgtgctg ttcagttcat ccagcagtcg
     4021 ctcaagacgc aaagccagct gctgccctgc atctgtaagc accacttcac gcgtggttct
     4081 gtccagcagg cgaacaccag tatgattttc cagttccttc acactgtgac tcactgccga
     4141 ctggctcagg ccgatacgct ctcctgcacg actaaaactt ttctcctgcg ctactgtgac
     4201 gaaaaccttt aattgtttta aagaataatt catctgtttt cttcatgaat ggatgcaata
     4261 aatcaatttt atttctcaaa ctggaagaag cacaatagaa ccatcgatca tctggagtct
     4321 ttatgaaact ttttcgtatc ctcgatcctt tcaccttaac cctgatcacg gtggtgttgc
     4381 tggcctcttt ctttccggcc agaggcgatt tcgtcccctt ctttgaaaat ctgaccaccg
     4441 cagctattgc cctgctgttc tttatgcacg gcgcgaagtt gtcgcgtgag gcgattattg
     4501 ctggcggtgg tcactggcga ctgcatttgt gggtaatgtg cagcaccttc gtgctgtttc
     4561 cgattctggg tgtactgttt gcctggtgga aaccggtaaa tgtcgacccg atgctctact
     4621 ccggttttct ctacttgtgc attctcccgg ctaccgtgca gtctgcaatc gccttcacgt
     4681 caatggcggg cggtaacgtc gcggcagcgg tttgttctgc gtcggcatcc agcctgctgg
     4741 ggattttcct ttcaccattg ctggttggtc tggtgatgaa tgttcacggt gcagggggca
     4801 gccttgagca ggtcggtaaa attatgctgc aactgctgct gccgtttgtg ttggggcatc
     4861 tttcccggcc gtggattggt gactgggtgt cgcgcaataa aaaatggatt gcgaaaactg
     4921 accagacgtc cattctgttg gtggtttata cagcgttcag cgaagccgtc gttaatggta
     4981 tctggcataa agttggctgg ggatcattgc tgtttatcgt ggtggtcagc tgcgttcttc
     5041 tggctatcgt gattgtagtt aacgtcttta tggcacgccg actgagcttc aataaggcag
     5101 atgaaattac tatcgtcttt tgtggttcga aaaagagtct ggcaaatggc atcccgatgg
     5161 caaacattct gttccccaca tcggtgatcg gtatgatggt gctgcccctg atgattttcc
     5221 atcagatcca attgatggtc tgtgcggtgc tggcgcgtcg atacaaacgc cagaccgaac
     5281 agttacaggc gcagcaggaa agcagcgccg ataaagctta aagcggacgc ttcaggggct
     5341 ggaccagttg cgtcagcccc tcggttttaa tcagcagcgt gatttgcatt agctcaccga
     5401 gcttccctgc cgggaactca tctttgcggg caaaccacag cagatactcc tccggcaggt
     5461 cgattaagcg acgccctttg tatttgccaa acggcattat cgtattggct atttcaatca
     5521 gctgctcttt ttccatctca gctacccagc aaacgcagca tttccgcttc gtcgatgact
     5581 tcaatgccca gttcctgcgc cttcgccagt ttagatcctg cagcttcacc cgctatcacc
     5641 agatcggttt tcttcgacac gctgcccgcg actttcgcgc ccagttcgac cagtcgagct
     5701 ttagcgtcat cacgcgacat ctggcttaag ctgcccgtaa gcaccacggt tttaccagca
     5761 aacgggctgt caatctcttc cgcgttgata acgatcggcg caggccagtg aacaccttcc
     5821 gccaacagct cgctgatgac attgcggttg ctttcttcgg caaagaagtt gtgaacgtgg
     5881 gatgcaacga caatgccaac atcaggcacc ttttgcagct cttcaatcga agcggcttcc
     5941 agcgcttcca gcgtgccgaa atatgccgcc agacctgctg cggtggcctc gccgacttca
     6001 cggatgccaa gtgcatagag gaagcgagca aaggtggttt ctttcgcttt ttccagcgcg
     6061 ttaaccacgt tttgtgccga ttttggcccc atacgctcca gtccggtcag tttgcctgcg
     6121 gtgagtttga acagatctgc cggagtatgg acatattctt tttcaaccag ctgatcgatg
     6181 attttgtcgc ccattccgtc aacatccatc gcacggcggg aaacaaagtg tttcagcgac
     6241 tctttacgct gcgcaccgca aatcaggcca ccggtacagc gggcaaccgc ttcaccttcc
     6301 acacgctcaa cgtcagaacc acataccgga caatgcgtcg ggaatacaac ctcacgggta
     6361 tcttccgggc gttcagaaag cacgacgtta accacctgcg ggatcacgtc gccagcgcgg
     6421 cgaatcacca ctttatcgcc aatgcgtaaa ccaagacgtt cgatttcatc cgcattgtgt
     6481 aaggttgcgt tactcaccag cacgcctgca acatggacag gttccagacg cgcaacaggc
     6541 gtaatcgcgc cagtacgccc aacctgaaac tcgacgtcac gcacaaaggt catctgctcc
     6601 tgcgccggga atttaaacgc taccgcccag cgcggggcac gcgcgacaaa gccaagctgc
     6661 tcctgctgtg ccagtgagtt gaccttaatc accacgccgt cgatatcaaa gcccagcgtc
     6721 gggcggtctt cttccacttt gtgatagaac gccagcactt cttccgccga ttcacaaagc
     6781 gttacccgat cgctgaccgg caacccccac tttttaaatt gcagtaaacg gccaagatga
     6841 gtatccggca gctcgccacc ttccagaaca ccaacgccat agcagaaaaa agtgagcggt
     6901 cgcttcgctg taatacgcgg atcaagctga cgcagtgaac cagctgccgc attacgtggg
     6961 ttagcaaaca ctttcccgcc cgtgcgtcgc gcatcttcgt taatcttttc gaaccccgcc
     7021 tgcggcagga acacttcacc acgcacttcc agacgcgccg ggatattctc tccgtgcagc
     7081 ttcagcggaa tggcgcgaat agtacgcaca ttagacgtga tatcttcccc ggtggtgcca
     7141 tcgccacggg tcgcggcact gactaaaacg ccattttcat acagaatact gacggcaaga
     7201 ccatccagct tcagctcaca gcaccaggtg actttctcgt tgtttttcag acggtcctgc
     7261 acacgtttgt tgaaagcaag aaagctttct tcatcaaaaa cgttatccag tgacagcatt
     7321 ggtacttcat ggcgtatctg gctgaaagcc gccagcggcg cagcgcctac acgttgagta
     7381 ggcgaatcag gcgtaatcag ttctggatgt ttggtttcca gctcgcgcag ttcgcgcatc
     7441 agcctgtcgt attcagcgtc gggaatttcc ggcgcatcca tcacatgata aagatattca
     7501 tgatggcgaa gcgtcgttcg cagttctgtc agttgttgtt cgattgattc catatcgcac
     7561 catcaatgct aaaaaccccc gacaagcggg ggttcgaaga ggagttaatt tgccttaagt
     7621 gtatcaggcg ttggcgtctt tgacttcgcg gatgatgtcc tggtactcgc gcaatttctg
     7681 cggagtcatc atacggcgct gatcgtcaag cacgacaccg cccacttcat cggcaatatg
     7741 ctgcgcagat tgcagcatca gcttgaagtt ctgcagctcg tcaccgtaag acggtacctg
     7801 cataaagata gtgacacccg gagtagtgaa atccttcatt tcaggatcaa aggttcccgg
     7861 tttcaccata ttcgccaggc tgaataacgc cgggccgctg ccatccgggc taagatgacg
     7921 atggtaaata ttcatatcgc caaaaatgaa gcccgcttgt tgaatgctgt taagaagcag
     7981 ttcaccgttt agctcgctac cgtgatgcgc cgcgacgttc atgataatca ccgcttcttt
     8041 gcgcttcggt ttatccataa ctggagcagg ttccgctaca ggctcaggct gtggtgccgc
     8101 tacgggttct gcaggctgga aagcctgttg tgccggttgc ggtgctgaat gcacaggctg
     8161 cggcgctggc gcgacctgtg gcgaaactgg ctgctgcaac ggctgttcag gctgcggctg
     8221 ataggcaggc tgctgcaccg gctgcgctgg atgcggagca tgttgcggcg gtacctgcgc
     8281 ttcaggcggc tgctggaccg gttgacgcgg ctgcgcagac gcataaggcg gttggtactg
     8341 gtgttgcggc gacggacgag cagcctcatg ctcctgagcg ttagccgggg catgattcac
     8401 gcggtgaaca cgaacctcac caacgccctc atcatcttcg acatcctcgt cataagaatc
     8461 gtcgtcacgt tttgacttca ttcgttttaa tggccgatcg cggaacatag aagatcgttc
     8521 tttacggctg gtccagaaac catgtaccag taaagcgatt atggcgatcg cgccaacaat
     8581 gattaatatc agacgcaaat cctgcatcat tatattctct gttgttctaa caccttgcca
     8641 ccacggcaaa catttactca ctaagagtat ttgccgatta cctcaagtgc aagtgcacta
     8701 ttaactttca cagcacaaag atagatgaaa tcgtgctttt tgctgttttt tcgaacatat
     8761 cctaactgtc cattgcgcaa ttacccggta aaatacgcag aattttcctg ggattggtca
     8821 aaaggagctc atcctgatta tggtttcatc attcacatct gccccacgca gcggttttta
     8881 ctattttgcg caaggctgga agctcgtctc gcaacctggg attcggcgtt tcgttatttt
     8941 accgctgctg gtcaatattt tgttgatggg gggcgcattc tggtggctct ttacacagct
     9001 cgatgtctgg atcccgactc tcatgagtta cgttccggac tggctacaat ggctgagtta
     9061 tctgttgtgg cctctggctg tcatctctgt gctgttagtg tttggctatt tcttctccac
     9121 gattgctaac tggattgccg ctccgtttaa cggtttattg gctgaacaac tggaagcacg
     9181 attgactggc gctacaccgc cagataccgg gattttcggt atcatgaaag atgtgccgcg
     9241 aatcatgaaa cgcgaatggc aaaaatttgc ctggtatctg ccgcgcgcaa ttgtattact
     9301 aattctttac ttcatccctg gtattgggca aaccgtcgcg ccggtactgt ggttcctgtt
     9361 tagcgcctgg atgttagcca tccagtattg cgattacccc ttcgataacc acaaagtgcc
     9421 gtttaaagag atgcgcaccg ccctgcgcac acgcaaaatc accaatatgc agtttggtgc
     9481 tttaaccagc ctgtttacga tgatcccgct gcttaatctg ttcatcatgc ccgttgccgt
     9541 ttgtggcgcg acggcgatgt gggtcgattg ctatcgcgat aaacacgcga tgtggcggta
     9601 acaatctacc ggttattttg taaaccgttt gtgtgaaaca ggggtggctt atgccgcccc
     9661 ttattccatc ttgcatgtca ttatttccct tctgtatata gatatgctaa atccttactt
     9721 ccgcatattc tctgagcggg tatgctacct gttgtatccc aatttcatac agttaaggac
     9781 aggccatgag taagattttt gaagataact cgctgactat cggtcacacg ccgctggttc
     9841 gcctgaatcg catcggtaac ggacgcattc tggcgaaggt ggaatctcgt aaccccagct
     9901 tcagcgttaa gtgccgtatc ggtgccaaca tgatttggga tgccgaaaag cgcggcgtgc
     9961 tgaaaccagg cgttgaactg gttgaaccga ccagcggtaa taccgggatt gcactggcct
    10021 atgtagctgc cgctcgcggt tacaaactca ccctgaccat gccagaaacc atgagtattg
    10081 aacgccgcaa gctgctgaaa gcgttaggtg caaacctggt gctgacggaa ggtgctaaag
    10141 gcatgaaagg cgcaatccaa aaagcagaag aaattgtcgc cagcaatcca gagaaatacc
    10201 tgctgctgca acaattcagc aatccggcaa accctgaaat tcacgaaaag accaccggtc
    10261 cggagatatg ggaagatacc gacggtcagg ttgatgtatt tattgctggc gttgggactg
    10321 gcggtacgct gactggcgtc agccgctaca ttaaaggcac caaaggcaag accgatctta
    10381 tctctgtcgc cgttgagcca accgattctc cagttatcgc ccaggcgctg gcaggtgaag
    10441 agattaaacc tggcccgcat aaaattcagg gtattggcgc tggttttatc ccggctaacc
    10501 tcgatctcaa gctggtcgat aaagtcattg gcatcaccaa tgaagaagcg atttctaccg
    10561 cgcgtcgtct gatggaagaa gaaggtattc ttgcaggtat ctcttctgga gcagctgttg
    10621 ccgcggcgtt gaaactacaa gaagatgaaa gctttaccaa caagaatatt gtggttattc
    10681 taccatcatc gggtgagcgt tatttaagca ccgcattgtt tgccgatctc ttcactgaga
    10741 aagaattgca acagtaatgc cagcttgtta aaaatgcgta aaaaagcacc tttttaggtg
    10801 cttttttgtg gcctgcttca aactttcgcc cctcctggca ttgattcagc ctgtcggaac
    10861 tggtatttaa ccagactaat tattttgatg cgcgaaatta atcgttacag gaaaagccaa
    10921 agctgaatcg attttatgat ttggttcaat tcttccttta gcggcataat gtttaatgac
    10981 gtacgaaacg tcagcggtca acacccgcca gcaatggact gtattgcgct tttcgtgcgt
    11041 cgcgtctgtt aaaaactggc gctaacaata caggctaaag tcgaaccgcc aggctagact
    11101 ttagttccac aacactaaac ctataagttg gggaaataca atgttccagc aagaagttac
    11161 cattaccgct ccgaacggtc tgcacacccg ccctgctgcc cagtttgtaa aagaagctaa
    11221 gggcttcact tctgaaatta ctgtgacttc caacggcaaa agcgccagcg cgaaaagcct
    11281 gtttaaactg cagactctgg gcctgactca aggtaccgtt gtgactatct ccgcagaagg
    11341 cgaagacgag cagaaagcgg ttgaacatct ggttaaactg atggcggaac tcgagtaatt
    11401 tcccgggttc ttttaaaaat cagtcacaag taaggtaggg ttatgatttc aggcatttta
    11461 gcatccccgg gtatcgcttt cggtaaagct ctgcttctga aagaagacga aattgtcatt
    11521 gaccggaaaa aaatttctgc cgaccaggtt gatcaggaag ttgaacgttt tctgagcggt
    11581 cgtgccaagg catcagccca gctggaaacg atcaaaacga aagctggtga aacgttcggt
    11641 gaagaaaaag aagccatctt tgaagggcat attatgctgc tcgaagatga ggagctggag
    11701 caggaaatca tagccctgat taaagataag cacatgacag ctgacgcagc tgctcatgaa
    11761 gttatcgaag gtcaggcttc tgccctggaa gagctggatg atgaatacct gaaagaacgt
    11821 gcggctgacg tacgtgatat cggtaagcgc ctgctgcgca acatcctggg cctgaagatt
    11881 atcgacctga gcgccattca ggatgaagtc attctggttg ccgctgacct gacgccgtcc
    11941 gaaaccgcac agctgaacct gaagaaggtg ctgggtttca tcaccgacgc gggtggccgt
    12001 acttcccaca cctctatcat ggcgcgttct ctggaactac ctgctatcgt gggtaccggt
    12061 agcgtcacct ctcaggtgaa aaatgacgac tatctgattc tggatgccgt aaataatcag
    12121 gtttacgtca atccaaccaa cgaagttatt gataaaatgc gcgctgttca ggagcaagtg
    12181 gcttctgaaa aagcagagct tgctaaactg aaagatctgc cagctattac gctggacggt
    12241 caccaggtag aagtatgcgc taacattggt acggttcgtg acgttgaagg tgcagagcgt
    12301 aacggcgctg aaggcgttgg tctgtatcgt actgagttcc tgttcatgga ccgcgacgca
    12361 ctgcccactg aagaagaaca gtttgctgct tacaaagcag tggctgaagc gtgtggctcg
    12421 caagcggtta tcgttcgtac catggacatc ggcggcgaca aagagctgcc atacatgaac
    12481 ttcccgaaag aagagaaccc gttcctcggc tggcgcgcta tccgtatcgc gatggatcgt
    12541 agagagatcc tgcgcgatca gctccgcgct atcctgcgtg cctcggcttt cggtaaattg
    12601 cgcattatgt tcccgatgat catctctgtt gaagaagtgc gtgcactgcg caaagagatc
    12661 gaaatctaca aacaggaact gcgcgacgaa ggtaaagcgt ttgacgagtc aattgaaatc
    12721 ggcgtaatgg tggaaacacc agctgccgca acaattgcac gtcatttagc caaagaagtt
    12781 gatttcttta gtatcggcac caatgattta acgcagtaca ctctggcagt tgaccgtggt
    12841 aatgatatga tttcacacct ttaccagcca atgtcaccgt ccgtgctgaa cttgatcaag
    12901 caagttattg atgcttctca tgctgaaggc aaatggactg gcatgtgtgg tgagcttgct
    12961 ggcgatgaac gtgctacact tctgttgctg gggatgggtc tggacgaatt ctctatgagc
    13021 gccatttcta tcccgcgcat taagaagatt atccgtaaca cgaacttcga agatgcgaag
    13081 gtgttagcag agcaggctct tgctcaaccg acaacggacg agttaatgac gctggttaac
    13141 aagttcattg aagaaaaaac aatctgctaa tccacgagat gcggcccaat ttactgctta
    13201 ggagaagatc atgggtttgt tcgataaact gaaatctctg gtttccgacg acaagaagga
    13261 taccggaact attgagatca ttgctccgct ctctggcgag atcgtcaata tcgaagacgt
    13321 gccggatgtc gtttttgcgg aaaaaatcgt tggtgatggt attgctatca aaccaacggg
    13381 taacaaaatg gtcgcgccag tagacggcac cattggtaaa atctttgaaa ccaaccacgc
    13441 attctctatc gaatctgata gcggcgttga actgttcgtc cacttcggta tcgacaccgt
    13501 tgaactgaaa ggcgaaggct tcaagcgtat tgctgaagaa ggtcagcgcg tgaaagttgg
    13561 cgatactgtc attgaatttg atctgccgct gctggaagag aaagccaagt ctaccctgac
    13621 tccggttgtt atctccaaca tggacgaaat caaagaactg atcaaactgt ccggtagcgt
    13681 aaccgtgggt gaaaccccgg ttatccgcat caagaagtaa ttcttgccgc agtgaaaaat
    13741 ggcgcccatc ggcgccattt ttttatgctt ccgccagcgg cggcaaaatc aattcatcgc
    13801 tctcatgctg ctgggtgtag cgcatcactt ccagtacgcg caaccccgct cggtgcactg
    13861 catcggttaa cgccttccct ttcagcaagc cactgatgag ctgagcacaa aacaggtcgc
    13921 cagtcccttt caggtcggtt tttacccgtg aatgggaaat gacattcacg ctgtcggcag
    13981 tgaccaccac aacctgcatc tcctgatttt cttcattacc ggaggcgctg gtaaccacca
    14041 cccattttaa tgtgtctgaa agcagacttt ttgcggcagc aatggcactg tcgagatcgc
    14101 ggcaattttt accggtcagg atttccaact caaagatatt gggggtaatt ccctgcgcca
    14161 gcggcagtaa atattgtcga tacgcttcgg gaaggtcagg tttgacataa attccgctat
    14221 caatatcgcc aatcaccgga tcgaccatga tcaataggtc aggatggtct ttgcgtagcg
    14281 cagtcagcca ctcggcaagg attttgattt gcgatgccgt tcccatatag cccgtggtta
    14341 cagcacgaag ttggcgcagc gcatcacgct cctgaagcgc acgcaaatag ccgctaaacc
    14401 attcgtccgg aatcgcacca ccgtagaaag tgtcataatg cggcgtattg ctcagcaata
    14461 ccgtcggcac ggcaaagaca ttcaggccgt tctgtttgat agcaggcacg gcaatgctgt
    14521 tgcccacgct gccgtaaacc acctgcgact gcacggcgac gatatccgcc tgcagtgccc
    14581 tactcttatc gttaaacaac aacaaactac tcatttaatt ttttctcctt gccgatgatc
    14641 ctcatcgtaa tccaaccgaa actttacctg attctggcag tcaaatcggc tatcacaaaa
    14701 caaggataag gtaattcaat gaagaaaatc atttgtctgg tcattacact actaatgaca
    14761 ctccccgttt acgcgaagtt aactgcccat gaagaagccc gcatcaacgc catgctggag
    14821 ggattagcac agaaaaagga tttgatattt gtgcgcaacg gtgatgaaca tacctgctat
    14881 gaagcggttt ctcatctgcg tctgaagctc ggcaataccc gtaaccgcat tgacactgcc
    14941 gagcagttta ttgataaggt tgcttcgtcg tcatcgatta ctgggaagcc gtatattgtg
    15001 aagatccccg gtaagagcga tgagaacgca cagccttttt tacatgcgtt aattgcgcag
    15061 acggataaaa cggtgcctgc ggaaggaaat taatccgctt tgggaaggca tttacaggag
    15121 gtaacatgaa aaaacgcttt atttatcacg atgaaaaatc gaataaattt tggtggatag
    15181 attacgaagg ggatagttta gctgtcaact atggcaaggt aggtagtatt ggtaaattcc
    15241 agacaaaaga gttcgataat gaagaacagt gtctgaaaga agccagtaaa ttgattgccg
    15301 caaaaatgaa gaaaggctat caagaagatc caaagtttaa cttcatggat cgctactatt
    15361 ttgatgatga agaaattggg ttacatgtta aaacgtcaca cccaaacttc cagtgccatt
    15421 ttactgatcc actttatatg tgttgctggg atgaagaatc tccttttggc agcgatgaag
    15481 gtgctgatgc tctaaacgtt cttgaaaata gcctccgtaa agagccggat ctggactgtg
    15541 ctgatttccc tcaaatgtta attgaaacta tgtggggtat gaaatacatc gctatggaca
    15601 gtattcttga agaggatgtt cgtgcgcaat tactagtcga tgaaatgagc actatccaga
    15661 gcaatatgat tacctacgca actgcattcg gtcagattaa agtcatgggt aaaatctccc
    15721 ataaacttaa aaagatggga ctcaatgcac tagcgcgtca tcagcttacc gcaaaaattc
    15781 ttcaatgggg tgacggtcag gactcaccaa tacttcaaaa aatgattgat gaccttacgg
    15841 cgtttcctca cgaaaattaa atactgcatt tgtcggcagc aacaactgtt aaaaaagtgc
    15901 gctttgttta tgccggatgc ggcgtaaacg ccttatccgg cctacaaaat cgtgctaatt
    15961 caatatattg cagaaacctt gtaggcctga taagcgtagc gcatcaggca gttttgcgtt
    16021 tgtcatcagt ctccgatgct attaatcctt aaatccccgc cccctggcta aaatgctctt
    16081 ccccaaacac cccggtagaa aggtagcgat cgccacgatc gcagatgatc gccaccacca
    16141 ccgcgtcagg gttagctttt gccacccgca gtgctccggc aaccgcgccg ccggagctga
    16201 cgccacagaa tattccttcc cgcaccgcca gttcgcgcat ggtgttttcc gcatcgcgct
    16261 gatgaatatc cagcacctca tccaccagag aagcgttgaa aatccccggc agatattccg
    16321 taggccagcg gcgaatgccg ggaatgctgc tgccctcttc cggttgcagg ccgacaatgg
    16381 tcaccggttt ggattgttcg cgcataaagc gtgagacgcc ggtgatagtg ccggtcgtcc
    16441 ccatgctgga gacaaaatga gtgatgcgcc cgccggtttg ctgccagatt tccggcccag
    16501 tggtggtgta atgcgcataa gggttatcgg gattattgaa ctgatcgagc agctttcctt
    16561 cgccacgatt cgccatctcc agcgccagat cgcgcgcacc ttccatgccc tgctctttgg
    16621 tgacaagaat cagttccgca ccataagcac gcatcgccgc acggcgttcc tggctcatgt
    16681 tgtcgggcat cagcaatttc atgcgatagc ctttcagcgc ggcaatcatt gccagcgcaa
    16741 tgccggtgtt accactggtg gcttcgatta agacatcacc cggtttaatt tccccgcgct
    16801 tttccgcctc gacgatcatc gaaagtgccg cacgatcttt caccgaacct gccgggttat
    16861 tgccttccag ttttaaccac acttcactgc cgttatccgg ccccattcgc tgcaacttca
    16921 ccagaggcgt attgcctatt gtttgttcta atgtactcac gatctctatc catacgtggt
    16981 gttgcctgat gcgacgcttg cgcgtcttat caggtctaca ggttacaaac cttgccatta
    17041 aaaagcccgg atcgcgggaa gcgcctccgg gcgtttaaca ttcactcaac ctatcaggcg
    17101 ctttgtgcga gagcaagttc ctcatcgcga gtttcgatac gctcgtcgcc gttatacagc
    17161 cgcgcatgtt gcagaccaac gaataaacgc tcgccacgct gcggggcatc gtcgccatgc
    17221 atcacgaccg tcagcggttc gttgtaccac cccagcggct gcaccactaa ttgggtgtag
    17281 tgacctttcg ggctggcttc cagtacctgt accggcagcg gcgaatcgag gctggtacgg
    17341 cggctgatat ccacttccca agggcgcagg aagagatcca ccggcccctg atacgcaggt
    17401 gtgtagccca gcggccagcg atgcgcgcca acatggaact gcccgccgcg aatggttccc
    17461 tgcaggcggt tcacttcgcc cataaattcg agcacaaaac gggtcgccgg ttcgcgccat
    17521 acctgatccg gcgcgtcagc ctgttcaata ttgccctggc tcatcacaac tacacgatca
    17581 gctacttcgg tcgcttcttc ctgatcgtgg gtcacaaaaa cgctggtgaa ttttagttct
    17641 tcatggagtt gacgcagcca gcgacgcagc tctttacgca cctgcgcatc cagcgcgcca
    17701 aacggttcat caagcagcag aatttgcggt tccacagcca gcgcgcgcgc cagcgccacg
    17761 cgctgtttct ggccgccgga aagctgcgcc ggataacgat ccgccagatg ggcaagctgg
    17821 accatttcca gcaattttgt cactttcgct ttgatggctg cggcattcgg gcgctcgcga
    17881 cgcggcagca ccgtcaggcc aaaagcgata ttgtcgaaca ccgtcatatg gcggaacagc
    17941 gcgtaatgct ggaacacgaa accgacttta cgatcacgtg cgtgcaggcg gctcacgtcg
    18001 gtgccgtgga agcgaatatg cccgctggtt tgatgctcca gcccggcgat aatgcgcagc
    18061 agcgtggttt tcccggaacc ggacggcccc agcaacgcga ccatctgacc tgaaggaata
    18121 tccagtgaga tatcgttcag cacctgggtg cgaccaaacg acttcttaat attggcaatc
    18181 tcaatgctca tgatgttcct cctgctgtgc gcgtttttcc tgattctcca ggcgccactg
    18241 caacatactt tttaaaaaca gggtgataat cgccatcagc gttaacagcg ccgcagcggt
    18301 aaaggagccg acggtgttgt agtcctgctc cagcaattca atctgtaacg gcagcgacag
    18361 ggtttcgccg cgaatcgagc cggaaaccac cgacaccgcg ccaaactcgc caattgcgcg
    18421 ggcgttggtc aacaccacgc cataaagcag cgcccagcgg atgttcggta atgtgacgcg
    18481 acggaacatc tgccagccgg acgcgccaag caaaatcgcc gcttcgtctt cctggctgcc
    18541 ctggcttaac atcaccggca ccagttcgcg caccacaaac ggacacgtca cgaagatggt
    18601 gaccagcacc attcccggcc aggagaacat aatttgcagg ttatgctcgt cgagccaacc
    18661 gccgagcggg ccgttagagc cgtagaacag caaatacacc agaccggcaa ccaccggcga
    18721 tacggcaaac ggaatgtcca gtagcgtcag cagtaactgg cgtccaggga agttaaagcg
    18781 cgtcaccagc caggccagca gaatgccgaa caccaggttt accggtacgg caatcagcgc
    18841 gatcatcacc gtcagccaga tggcgtgcag catgtccgga tcggccagat tctgtaaaac
    18901 cggcatcagc cccttgctga atgcctgcac gaagatgtaa atcatcggca ccagcaggat
    18961 gaacgccgaa accagcatcc cgatgccaat cagaaaccat ttgccccagt taatcgggcg
    19021 cgcgtcataa cgcttcaatt gggtaacttc cgccattaat gacctaccac acgccgacca
    19081 aagcgacttt gcagagtgtt aattgagaac agcagcagca gagatgccgc gaggatcacc
    19141 gaagcaatcg cgctcgctgc cgggtaatca aactcctgta agcgcacaaa aatcatcagc
    19201 gacgtcactt ccgtcttcca cgcgatattt ccggcgataa aaatcaccgc gccaaattca
    19261 ccaagactac gggtaaacga cagcgccacg cccgccacca gcgccggaga aagctccggc
    19321 agcaccactt tgcagaaact ctgccagcgc gttgcaccaa gcgtttccgc cgcttcttca
    19381 tattccgggc ctaactcttc cagcaccggc tgcacggtac gcaccacaaa cggaatgctg
    19441 gtaaaggcca tagccaccgc aatccccagc catgtatagg tgactttgat atcaaacttc
    19501 gccagccatt caccgtaaaa accgtttacg gaaaagagcg aggccagcgt taaaccggcg
    19561 acagccgttg gcagcgcaaa gggtaaatcc atcagcgcat caagcagcgt gcggcctggg
    19621 aagcgatagc gggttaggat ccacgccatc agcagaccga aaacgccgtt aaaaatcgat
    19681 gccacaaacg ccgacagcag cgttactttg taggccgcga ccacctgcgg gttggtgatc
    19741 acctcccagt actgcgccca gctcatctgg gccagttgca tcaccagcgc ggagagcggc
    19801 agcagcaaaa tcaggcacac aaacagcaga ctggtgccga ggcttaaggt aaagcccggc
    19861 agcacgcgtc tggaggagac agcaaacatc agttacgccc cgccgctaac agcttgtcta
    19921 actcgccgcc gctggtgaag tgggttttca tcacttccgg ccaggagcca aatttgtctt
    19981 ccacgcggaa cagctcggtc tgcgggaatt tgtctttcag tttgtccatc acctccgggt
    20041 tattcacgcg gtagtaatag tcggtgatga tggtttgcgc ctgcgggcta tagagccagt
    20101 tcagataggc tttggcggct ttttccgtac cgttggcctg cacgttttta tcaacccacg
    20161 ccaccgggaa ttccgccaga atgttggttt tcggaatcac cacttcaaag ccctgcgctt
    20221 catactgttt acggatgttg ttcacttccg attcgaagct aatcagcaca tcgcccaggc
    20281 cgcgctcggc aaaagtggtg gtcgcgccac gaccgccagt atcgaacact tcaacgtttt
    20341 tcaggaactg ggtcataaac tgttcggttt tgcctttgtc accaccgtca gctttatccg
    20401 ctgcgcccca tgccgccaga taggtataac gcgcgttacc cgacgttttc gggttcggga
    20461 aaatcagctt cacgtcggag cgcaccaggt cgttccaatc gtggatattc ttcgggttac
    20521 ccttacgcac caggaagccc atggtggagt agaacggcga gctattattc ggcaggcgcg
    20581 actgccagtc ggccgggatc agcttgcctt tatcgtgcag gatttgtacg tcggtcacct
    20641 ggttataagt gacaacgtcg gcttttaagc cctgtaaaat cgccagcgcc tgttttgatg
    20701 acccggcatg agattgtttt atcgtcagtt tgtcgccgcc gttatctttt gcccattgtt
    20761 gctcaaacgg cggattcagg gcggcaaaca gctcgcggga gacgtcataa gaactgttca
    20821 gcagttccgt tgcctgtaca tggcccgcca gcagcagaga agcgaccagc gcgagtgagt
    20881 tctttttcag taagttaacg gccattgcgc acccttataa atttaatgac tttctaatag
    20941 ccatcatatt tataacggac gtgaaaggag taacggtttt atataccgtt tggtgatttg
    21001 gaagttgaaa agggaataag aacttggttc aacaggcgta attgttgcag tcagtttgga
    21061 cacgaacagc gcggagaaac cggagcgtac acatagtacg tgaggatttc gagcactgcc
    21121 cggggccaaa atgacaaata aaatagcctg gtgaacttag ttcaagacga aatcctcccc
    21181 acaaatgcag ggaggaaaca gaggtgaatc agataccgac gctaaccgtc tccggcagtg
    21241 tgctgccgcc atcaatcaca ttctgtgtac cggttaaata gctggattca tccgatgcga
    21301 ggaaggccgc cagttcgccg acttccagcg gatcggcgag gcgacgcatc gggattgctt
    21361 tcgccatttc agtcagcacc gactctggat cttccgggtt cgactggcgg gcaatgcttt
    21421 ccgccattgg tgtgcgcacg tatcccgggc aaatggcgtt aacgcgaata ccagactgcg
    21481 cgtactccac cgccagcgat tttgtcaggc caacaatcgc cgctttcgtt aaggcgtacg
    21541 ccgtttcgcc aggatcggcc accatatcac cagtgactga agacatcatc acaatgcgac
    21601 catctttgcg ggcaatcatc tccggcagca ccgccttcgt gacgttccat acgcctttaa
    21661 tattgatgtc aatatggaaa tcgcgatcgt catcgctcat atcgaggaaa ctgcccagac
    21721 gacaaacgcc tgcgttattc accaggatat caatgcgccc ttctttttcc ttcgcgcgtt
    21781 tgatagctgc ggctaccgac gccgggtcac gcacatcggc gacaaccgcc gtacagcgat
    21841 gaccacgacc acacagttcg tccgccagct tttcgatctc aggggagata tccagcaaga
    21901 ttaggttcgc gccatgacgt gcaaaagttc tggcaattcc ttcgccaatt ccctgcaatg
    21961 cgcccgtaat cagtgctgtc ttgcccgtga gtttacccat tttaatgctc tccttgttaa
    22021 tacagagcgt tacactccat tccctctgaa aatacaggat aaacaaaata ttgctgcgga
    22081 tcagctcact aattcaggaa aatctcaatc cagtcgctgc tttatgcatc atttcaggcg
    22141 ttgtgttagc tcactgctgc gctgaatcat tttcaatgac tccacatcat tgagttgcac
    22201 aaggccaaca aacagtaaat cggtaacaga attttgcgcc gtgcgggtag acatcgacga
    22261 gctacgccat tcggtttctc cggaaacggt atcgagggtg aaatgcgcca gccgccgcag
    22321 cggagagtca gtcagagaag taatggcaat caccgttgcc ccctgctttc gtgccgcttc
    22381 tgcgcacaag acaatctctt ttttactgcc gctgtaagag atagcgattt gtacatcgcc
    22441 ttttttcaac gcctgggaaa cggtggcttg tacgtgcgtg tcggcttcgc aggccacgcg
    22501 atagccaatt ttcatcagtt tgaacgacag atcgcgcccc accagcgccg atccgcccag
    22561 gcccgttatc tggataaacg gtgctttact gatgacctca atgatttttt gcagccgcgc
    22621 gtaatcgagc aacgcgcagg tttgctccag cgccagctct ttttcgcgat tcagtttgcg
    22681 cgcgatcact tccagcgaat catcactggt aatcgaactg tgcaggtgca gtgccgtggc
    22741 attcgttttc tcccggctgg cactgtattc gcctattaac gccatacgca attcagtaaa
    22801 tccttgcgcg ccgagttttt gggcaaattt cactatgctc gactggctaa tgccgagctg
    22861 tttcgccatc tgccgtgaag aaacggattg cagctcactc acgttggcct gcagaaagtc
    22921 agcgattttt tgctcgtttt cggtgaattc actccccgca ttgcttattt tcgtcaggta
    22981 caacatcttc cactctcctg ggctggcagc ataaattccg cttaagttct tatgacgctc
    23041 ttcacactct gcgagtgtag actcaatgat tcctttaagc ctgtcaattc gggatatatg
    23101 attccataca tctgcaatta tttgatcgta aatagtaagg tcaccaccga tgcaatttga
    23161 aaagatgatt actgaaggct cgaacaccgc ctcggctgaa attgaccgcg tatcgacgct
    23221 ggaaatgtgc cggattatca acgatgaaga taaaaccgta ccgcttgccg ttgagcgcgt
    23281 actgccggat atcgccgcgg cgatcgatgt tatccacgcc caggtaagcg gcggcgggcg
    23341 tctgatttac ctcggtgcgg gaacatccgg tcgtctgggg attctggatg ccagcgaatg
    23401 tccgcccacc tacggcgtga aaccgggtct ggtggttggt ttgattgctg gcggcgaata
    23461 tgccattcag cacgcggtgg aaggcgcgga agatagccgg gaaggcggtg ttaatgatct
    23521 gaaaaatatt aatttaacgg cacaggatgt ggtggttggc attgctgcca gcggtcgcac
    23581 gccgtatgtg attgccggac tggaatacgc acgccagctc ggctgccgca cagtgggaat
    23641 ttcctgtaat ccggggagcg ccgtttcaac caccgctgag tttgccatta caccgattgt
    23701 aggtgccgaa gttgttaccg gttcttcgcg gatgaaagca ggtacagcgc agaaactggt
    23761 gctcaatatg ctttccaccg ggctgatgat taaatccggc aaagtgttcg gcaacctgat
    23821 ggtcgatgtg gtcgccacca acgaaaaact gcatgtgcga caggtcaata ttgttaaaaa
    23881 cgccaccgga tgtagcgcag agcaagcgga agcggcgtta attgcttgcg agcgcaactg
    23941 taaaacggcc attgtgatgg tgctgaaaaa tctcgatgcc gcagaagcta aaaaacgcct
    24001 ggatcaacac ggcggcttta ttcgtcaggt tttagacaag gaataaccca tggccaaaga
    24061 gatcagcagt gaacttctga acaccattct tacccgtgtc ggcggaccgg gaaatatcgc
    24121 cagttgtggt aactgtatga cgcgcctgcg tctgggtgta catgacagtt cactggttga
    24181 tcccaatatc aaaacgctgg aaggcgtgaa gggcgtcatt ttgaccagcg accaggtgca
    24241 ggtcgttttt gggcctggta aagcgcatcg tgccgcaaaa gcgatgagcg agctgctggg
    24301 agaagcaccg gtacaggatg ccgcagaaat cgccgcccag aacaaacgtc agttaaaagc
    24361 caaacaaacc tccggcgtgc aacaatttct cgccaaattc gccaccatct tcacgccgct
    24421 gatccccggt tttattgccg ccggtctgct gctggggata gcgacgttaa ttgccacggt
    24481 gatgcacgtt ccggcagatg ctcagggaac actacccgat gcgctgaatt ttatgaaggt
    24541 gttcagcaaa ggtttgttca ctttcctggt gattctggtg ggctataacg ccgcccaggc
    24601 atttggcggc acgggcgtaa atggcgcaat tatcgccgcg ctctttttgc tcggttataa
    24661 ccccgcagcg accaccggtt actacgccgg ttttcacgat ttctttggtc tgcccatcga
    24721 tccgcgcggc aatattatcg gcgtgctgat tgccgcgtgg gcctgcgccc gcattgaagg
    24781 catggtgcgc cgctttatgc cggacgatct cgacatgctg ctgacctcgt taatcaccct
    24841 gctgatcacc gctacgcttg cgtacctgat cattatgccg ctgggtggct ggttattcga
    24901 aggtatgtca tggctgttta tgcacctgaa cagtaatccg ttcggttgtg cggttttagc
    24961 cgggctgttc ctgatcgccg tggtatttgg cgtgcatcag ggctttattc ctgtttacct
    25021 cgcgttaatg gacagccagg gattcaacag cttatttccc atcctttcaa tggcaggcgc
    25081 gggccaggtg ggcgcggcgc tggcactcta ctggcgggcg caaccgcaca gtgcgctacg
    25141 cagtcaggta cgcggggcga ttattcccgg cctgctgggc gttggtgaac cgctgattta
    25201 cggtgtcacc ctgccccgca tgaagccgtt tgttaccgcc tgtttaggcg gcgcggcggg
    25261 cggtttgttt atcggcctga tagcctggtg gggtctgccg atgggcttaa acagcgcctt
    25321 tgggccgtct ggtctggtag cgctgccgct gatgacttcc gcacaaggca tccttccggc
    25381 catggcggtt tatgctggcg ggattctggt ggcatgggtt tgcgggttta ttttcaccac
    25441 gctctttggc tgccgtaacg tcaatctgga ctgatatcat gaaacggaca atgctctatc
    25501 tttctctgct ggctgttagt tgtagcgtca gcgccgcaaa ataccctgtt ctgacagaaa
    25561 gctcgccaga gaaagcaggg tttaacgtcg aacggcttaa ccagatggat cgctggatta
    25621 gccagcaagt tgatgtcggt tatcccagcg taaacctgct gatcattaaa gataatcaga
    25681 ttgtgtatcg caaagcctgg ggagcggcga aaaagtacga tggcagcgtg ttgatggaac
    25741 agcctgtcaa agccaccacc gggacgctgt atgacctggc ctcaaacacc aaaatgtacg
    25801 ccacgaactt cgccctgcaa aagctgatga gcgaaggcaa actgcatcct gacgatcgga
    25861 ttgcgaaata tattccgggg tttgccgata gtccaaatga caccattaaa ggcaaaaaca
    25921 ccctgcggat ttctgacctg ctgcatcaca gcggcggttt cccggcagat ccgcaatacc
    25981 cgaataaagc ggtcgcgggc gcgttatatt cccaggataa aggccagacg ctggagatga
    26041 tcaagcgcac gccgctggaa tatcagcccg gcagcaaaca tatctacagc gatgtcgatt
    26101 atatgctgct tggatttatc gtcgagtcgg ttaccggtca gccgcttgac cgctatgttg
    26161 aagagtcgat ttatcgcccg ctcggcctga cacatacggt atttaacccg ctgctgaaag
    26221 gctttaaacc gcaacaaatt gccgccacgg aattgaacgg caatacccgc gatggcgtga
    26281 tccatttccc gaatatccgc acctccactc tctggggtca ggtgcacgat gaaaaagcct
    26341 tttattcgat gggcggcgtt tccgggcacg caggtttgtt ttccaatacc ggcgatattg
    26401 cggtgttaat gcaaacgatg ctgaacggcg ggggctatgg tgatgtgcag ctgttcaatg
    26461 cggaaacggt gaagatgttc accaccagct ctaaggaaga tgccactttt ggcctcggct
    26521 ggcgcgtgaa tggtaatgcc accatgacgc cgacgtttgg cacgctggca agcccgcaaa
    26581 cctacggtca cactggctgg accggaacgg tgaccgttat cgatccggtg aatcatatga
    26641 cgattgtgat gttaagcaac aagccacatt cgccggttgc cgatccgcaa aagaatccca
    26701 atatgttcga aagcggtcag ttgccgattg caacttatgg ttgggtagtt gatcaggtgt
    26761 atgcggcgtt aaagcagaag taataaaaag gccagtcagt aatgttactg gctggtctga
    26821 gagtgctgac aaacgcaaaa ctgcctgatg cgctacgctt atcaggccta cgtggagccc
    26881 acaatatatt gaattagcac gatttcgtag gccggataag gcgttcacgc cgcatccggc
    26941 gtgtacaacg cgcacttggt caacaatctg aggccagtca gtaatgttac tgcctggcct
    27001 ttaatcaatg aatcagaaac gcttacagcg ccatcaactt gtccagcgac ggtgcgaaat
    27061 aatagccgcc ggttaccggt ttggtgaaac gcaacatcgc atcacgctta ccatcggtat
    27121 cgccaaacat gctcagcagt tgctgctcaa tgttatgcag acgcgcgcag taggcgcaga
    27181 agtacagacc gtgagtgcca ctggcagtgc cgtacggcag gctctggcga acaatcttca
    27241 gccctttgcc atcttctttc agatcaacgc gggtgaggtg agaggtttcc ggacgttcgt
    27301 cgccgtcgat ctcttcgttg gcctctttgg tgcgcccgat catcatctcc tgatcgtgaa
    27361 cgctcatccg gttgagctgc ttcaggttgt gttcccaacg ctggacaaac acatagctgc
    27421 cgcccgcatc cacgccgtct ttgataaccg ccacttcgcg acgcgtctct tcacccgccg
    27481 ggttttccgt accgtcaaca aagccgctca ggtcacgctc ttcaacccaa cggaagccgt
    27541 ggatctcttc tttcacttca atgcagtcac caaaggcttc catcgccgcc tgggcgacag
    27601 agaagtttac gtcgtgacgc agagaaagaa tgtggatcaa cacatcgaac tgggtcgtcg
    27661 gcgcaaggcc tttaccgtag cccggaaaat ctttcagctc ttctgcccca acgccgccgc
    27721 tcagagcgcg ccaggtgttg ttaccaaagg caaccaccgc accaagatgc gcgtccggga
    27781 atttcgcttc aaaagttgcc agtttgtcgg caaatgtttt actggccgca cgcagggcgt
    27841 caacttcccc tttcacgttg gcttcgatcc aaatcgccgc gcggcaatgt tctggcaaaa
    27901 tgccactctg aacctgagac attgttcctc ctgaaaataa taatgccacg caatccgtgg
    27961 cattgttgag cgctatttta cgtgtttttt cgcggcggcg gtttgttcag acgcaaatta
    28021 acgccgccag ataattttac tgactttcca gtttttcagg gtatcgtccg aaggcattaa
    28081 cccttcagga ccacgccatt ccccgctgaa ctggtagcta atatgttgac tgccttcggc
    28141 tttacattcg acggcacgat tatcatcacc atcagctttt tggcaattgc caaatgcttt
    28201 gctgtaaagg tcgctaaacg gtgtaccgat tttaacaccg gtgtcagcag gaatatcgct
    28261 atccagcacg tcaatgcgac tgatcgtgcc ttgatcgccg ttaatcacca tcgccacgtt
    28321 gtcgcccttc atcacttcaa aaaagcgcac cacgttgccg ttcgcggttt tcattccgct
    28381 gcgcaggcga taatcgccat caagcgcatc ggcaatggct tgttcttgca gtggtgtgga
    28441 cgccgttaat tcacccacgc cctgctcgct cactttggtg gacgacccaa accagttcca
    28501 cgggttagcg gcagaccagt taactgacga catcgtggaa cagccggtca gcatcaatgg
    28561 catagcgcat aacattaaac gcagcgattt catgtcactt cctttggtta ttcaataacg
    28621 ttgcttggag tgcaaattca ccaaaaagtg ccgttattct tttacttcat taaaacaagc
    28681 gcgtaaacgt cgattggtca gcagccagat taacgccaca atatccgcca ctaccagcgc
    28741 cagaccgata ccgctaacgg attcaccgtt cagccacagc cacggttgcc agcaaagtaa
    28801 aaccacctgc gccaacagca acagaaaata gagtacacgc caggtgcgag gaaacgtagc
    28861 ccgccgaccg ctcaacaaaa acgccagcac cgccggaatg ccaggaatca gccccagcca
    28921 gaaattatcg tgatcgggat aaaacagatt tagcagcgca gtaccctgct cgcgcgacgc
    28981 accggcaatg acaaacagca cccaggttcg cgcctgaagc aatagcacaa gccagaagag
    29041 caagggtaaa cgcaggcgac cgtgcgcatc ataatggaca ggatgaaact cagtactctt
    29101 catcttcaat caaacgctta cccagactca gcacgtcggc gtgttcatat cccaggcgtt
    29161 catacattcc gagcaccatg tcgttatctt ccggcacatt gatctgaatt ttcgggcagc
    29221 cacgagcaat cagctttttc tccagccgat taagcaacgc attggcaatc ccacgcccac
    29281 gaaactctgg atgcacgcca agataataag cagacccgcg atgcccgtca taaccgccca
    29341 tcaccgttcc gaccacgtca ccgtttacct cagcgaccaa aaacaaactg acgtcatggt
    29401 tcatcttacg ctcgatgtcc atttccggat cgttccacgg acgcagcaag tcgcaacgct
    29461 cccaaagggt gatgacctct tcgaaatctt cctggcgaaa tacgcgtatc tccatggtat
    29521 tcgttacctt tttgcgggtt aaaaggctga ttatggcgtg aacggtcgaa ttagccaata
    29581 tctgacgaaa atcggttgaa aaagtggcat aatggggagt tgtcaactat tgaaatgaaa
    29641 agtaaaacaa ttctcaacag caaaccgtcg taacggatta cgcgatacga tataacatct
    29701 ggaactttat tattacaact caggccgtat gagcactttt aaaccactaa aaacactcac
    29761 ttcgcgccgc caggtgctga aagccggttt ggctgccctg acgttgtcag gaatgtcgca
    29821 agccatcgcc aaagacgaac ttttaaaaac cagcaacgga cacagcaagc cgaaagccaa
    29881 aaaatctggc ggcaaacgtg tcgttgttct cgatccaggt cacggcggaa ttgataccgg
    29941 agcgatcgga cgcaacggtt cgaaagaaaa acatgtggtg ctggcgattg ctaaaaacgt
    30001 ccgttccatt ttgcgtaatc atgggattga tgcgcgttta acgcgttctg gcgatacgtt
    30061 tatcccactt tacgatcgcg ttgaaatcgc ccataaacat ggcgcagatc tgtttatgtc
    30121 aattcatgcc gatggcttta ccaacccgaa agctgccggt gcttcggtat ttgccctctc
    30181 taaccgtggg gcaagtagcg caatggcgaa atacctgtct gaacgcgaaa accgcgccga
    30241 tgaagttgcc ggtaaaaagg cgactgacaa ggatcaccta ttgcaacaag tgctgtttga
    30301 tctggtgcaa acagatacca ttaaaaatag tctgacgctc ggctcgcata ttctgaagaa
    30361 gattaagccg gtgcataaac tgcacagccg caacaccgaa caagcggcat ttgtggtgtt
    30421 gaaatcaccg tcggttcctt cggtgctggt ggaaacctcg tttatcacca acccggaaga
    30481 agaacggctg ttaggcacgg cggcgtttcg tcagaaaatc gccacagcga ttgctgaagg
    30541 cgtgatcagt tatttccact ggttcgacaa ccagaaagca cattcgaaaa agcgataagt
    30601 tatgaaaccc gacgcacacc aggttaaaca gtttctgctc aaccttcagg atacgatttg
    30661 tcagcagctg accgccgtcg atggcgcaga atttgtcgaa gatagttggc agcgcgaagc
    30721 tggcggcggc gggcgtagtc gggtgttgcg taatggtggt gttttcgaac aggcaggcgt
    30781 caacttttcg catgtccacg gtgaggcgat gcctgcttcc gccaccgctc atcgcccgga
    30841 acttgccggg cgcagtttcg aggcgatggg cgtttcactg gtagtgcatc cgcataaccc
    30901 gtatgttccc accagccacg cgaatgtgcg gttttttatt gccgaaaaac cgggtgccga
    30961 tcccgtctgg tggtttggcg gtggcttcga cttaacccca ttctatggtt ttgaagaaga
    31021 tgctattcac tggcatcgca ccgcccgtga cctgtgcctg ccatttggcg aagacgttta
    31081 tccccgttac aaaaagtggt gcgacgaata cttctacctc aaacatcgca acgaacagcg
    31141 cggtattggc gggctgttct ttgatgacct gaacacgcca gatttcgacc gctgttttgc
    31201 ctttatgcag gcggtaggca aaggctacac cgacgcttat ttaccaattg tcgagcgacg
    31261 gaaagcgatg gcctacggcg agcgcgagcg caatttccag ttatatcgtc gcggtcgtta
    31321 tgtcgagttc aatctggtct gggatcgcgg cacgctgttt ggcctgcaaa ctggcgggcg
    31381 caccgagtct atcctgatgt caatgccgcc actggtacgc tgggaatatg attatcagcc
    31441 aaaagatggc agcccagaag cggcgttaag tgagtttatt aaggtcaggg attgggtgta
    31501 actccctcac ccccactccc gcatccgctg atgcagcgtc agtgacggct tctcggaaaa
    31561 cagctgctgg taatccgtgg caaattgccc cagatgccag aatccccact gcatggcggc
    31621 gtcttttacc gtcatacttt gcgaccacgg acttatcagt tcgcggcgta cggcgttcag
    31681 gcgaatgcgt ttcagccacg cgttcgggcc aatgcctaaa atagcgtgaa acgcgttttg
    31741 tagcgtgcgg cggctgacat gcagttgatt acacaaatcc agcaccgtca ccggttcgga
    31801 catgttttcc agcacatatt cacgggcgcg ggaaagcaat cgacggtaac tctgatgact
    31861 gatgctttcc gccgtcacca ttggttgcgc ttcttccagc atggccccca tcgccattag
    31921 caaattatcc cccagcactt ttcgcactgc aggctgatgg agattttccg gattctcgca
    31981 aaacgtcgcc agcgcctgtt ggacaaagcc ccacagcgcg gctttatgct gctctttcac
    32041 ttccagcgcc gactggttac gcaacatatg taatacccga tccgggttat gcaaaaagtt
    32101 agcctgccgg gtgatgacat cttcagaaag caccacgccc aggatcgtgt aatcatccgg
    32161 cgtgctcagt tcaaattcag tgccaccagg gcgggtggcg atttccgcgc ttcccagaca
    32221 ttgcgaaccg ataaatccct gctcaccgcg cgtcgccgga atgccaaacc agaacgagtt
    32281 cggccagacc aggcacgact gacgcagcgc cagaccggtg tattcacgaa aaacctgaat
    32341 atcatcgagt agaatttccg taaattcacc atgaaacttg cccggatgca gctgatcgta
    32401 aatctgctgc caggcggtaa tcgttaaagc atgttcatag acatccgttg tctgtcgttg
    32461 atgaacatta tccacttcga ccttcggcgt gagcttcagg ttttcgggta agggttcatg
    32521 ataaagatgg tgcaaattgg ctgtacgggt ctttttcatg atgttaatgc cgggtgttgt
    32581 aggacacccg gcacctccga caggttaatg gggcttgaga cgataacgac tactgcgttt
    32641 acgtaacgtc ccggcagaaa agagctgttc gagcgcattt ctggcttttt ccagcggcca
    32701 gccaaagtgg gcagccactt ctcctgccgt cattccctga cgtactgatg ttaacagcgc
    32761 caacaactcg tcagcagatt ccgcgacgat aactggcgcg tcgggttccc ttacgggttg
    32821 cttcggctgg cggttaaagc cagtaaccag ccactgggtg tcatcgtctg gccgaccgat
    32881 ctccttgcgg ctgatgacac gcccggtacg catcgcggca gcacaacctg cgtccagcgc
    32941 cgcacgacac gccgccagat cgccttccac caccagcgtt aagcgaccag ggtcaagcac
    33001 ttcgtgactg agcagacgaa cgttagctgc tttgagcatg gcatccgctg catctatcgc
    33061 ggcgaccatg ccgtccactt ccagcaatcc cagtgcattg atcatcggca acctccgtta
    33121 cgcacgctgg attggattac gcgcgatttc cagcactgca tcggtaaagg cgttacaggc
    33181 tgctttacac gctgcctggc taccggttaa aaatgctgcc gagtagttgg tttcagacgg
    33241 tggcgggaca taggtcgcca gctgtacgtc ggcagacttc agggctgcat caatgccata
    33301 ggtcgcttcc agcggcggtg ccaccagata cgccatcgga tcgccaagcg tgatcccggc
    33361 ggttgatgag agataagaac cggtacgcga aactacatgt gccaggaatg ccgtatcttg
    33421 cgcgtcatta gcccactgga aagctgcgcc attttcaata tgcgcaatca tcgcatccag
    33481 acctgcacgc acttccgccg ggtttggccc accaagcata atcagcactt caccggcagt
    33541 cggtgacggg ccgtgtgccg ctcccgcata cagcgagcga ccatatacca cttcgaccat
    33601 cgcttgtttg gtcgcttcgt cagccgcaat gtaggtgacg tcgtcagaat cggcagaaat
    33661 cagcccgagg ctacgaatat gcggcggcaa ttttagttca cgcgcaaatt cagcgttaac
    33721 ggaggcaatc acccgcatgg cggttaccga cggtcgaatc aaatctaaag ctggcatgat
    33781 gcctccttat cgggtcatgt tgatgccgga tgctttctgc tccagcatac gtttcgccaa
    33841 atccacaatg acggctgcgg cttcaaccgg cggcgtgccg ccctggtgaa tgttagagat
    33901 acaggtgcga tcggcctcaa cggtggtcgc catacgcggc gagtaaacgg cgtagcagga
    33961 gaggctttct gactgcccta accccggacg ttcccccacc agcaggatca ccactttcgc
    34021 gccgaggatc tcaccgatct gatcttcaat cttcacgcga ccataacgaa caaagaatgg
    34081 cgtgccgact ttcagcccgg cctgtttcag gcccgccatc agcggcggca ggatctcttc
    34141 gtagttgacg gtgatggcat cagttgacag gccatcagaa ataacgacct gtacgtccgg
    34201 attagcaaca cactgtgctt tcagcgcttc aacagcttct gcacacaggc ggcggcccat
    34261 atccgggcga gtcaggtaga gatttttgtc gctaatttca gagcgtactt ccagcaagcc
    34321 ctgcgctttc acccactctt ccggcacttc tttcagtacg gtatctttcg aacgagagtg
    34381 atcggccagg aaacgcagca gcgcctgggt acgtggacgc ggaccggcac gaccggtaca
    34441 aacgcgggcc acggtgctgc ggcgcagttc tgttaatacg tctgcgcgat gcgggttttc
    34501 aacaccaatc cacgcttttg cttcagcgga acctaaatcc agcgcacagc tttccgaggt
    34561 caccggtgcc gcacagttgg tggtggcgca ctttgcttct gacggcgcgg gggccgtttg
    34621 tcccattgac gccatcacgc tgcgtacaat ttcttcaatc tgtttttgat ccatgatgtg
    34681 ttatctccgc gtcatcagaa gaacagtgac ggatcgcccg cccgtttggt caggcgaccg
    34741 tttgccataa tgcccatgct ttccagccag cgttcaaact ccggtgacgg gcgcaggttg
    34801 agtaactgac gcacagtggc ggtatcgtgg aatgcggtgg tctggtagtt gagcatgatg
    34861 tcatcaccca gcggcatccc catgatgtag ttgcagcctg cggtggcgag caggatcatc
    34921 aggttttcgt tgaggttctg gtcagcgtca gcgtggttgg tataacagca gtcacagccc
    34981 atagagatgc cgctcagctt gcccataaag tgatcttcta agccagcacg gataatctgg
    35041 cggtcgttgt agagatactc cggcccaata aagccgacca cggtgttgac gataaacgga
    35101 tcgtaatgac gcgccagccc gtagttacgt gcttccatcg ttacctggtc tgcgccgaag
    35161 ttagcgccag cggatagcgc agagccttgt ccggtttcga agtagaggca gttttccccg
    35221 gcgatacggt tgaactccgc gcccactgcg cgcgcttcgt cgagcatcgc cagctccacg
    35281 ccaaactctt tcagcccttt ttcgctgcca cagatactct ggaaaatcag cccgcccggt
    35341 gcgccacgac ggatcgcttc gatctgggtg gtgacgtgcg ccagtacaca gccctgagtt
    35401 gggatgttga atttgtcgat cacgccatag atggtatcca acacgcggct taagttttcc
    35461 acgtcgtcag tcaccgggtt aacgccgatc accgcatcgc ccaccccgaa ggaaagccct
    35521 tcgtagattt gcgcggcgat actttgcacg tcgtcacggg tgtcatttgg ctgcaaacgg
    35581 gcgctaaagg tgcccggaat accgatggtg gtattggcct ttttgattac cggcattttc
    35641 ttcgcgccgt agatcaggtc cgcgttggag caaatcttcg ctaccgccgc gaccacttcc
    35701 gaggtcagcc ctttgcgggt aaaggcaatg tcgtccacgc tggtttcatc gctcagcaca
    35761 tactcacgca gttcgctgat gctccagttt ttaatctggt tgtaggccgt ttcgttaaca
    35821 tcgtcctgaa tcagccgcgt cacgcagtca tcttcatagg caatcaccgg attattgcgg
    35881 atgtccgcta cggtcatttc cgacaacacc tgctttgccg ccacgcgctc ctgtgagctt
    35941 gccgctgcga cgcccgccag cacatccccc gaacgcagtt cgttggcttt agccagcacc
    36001 tcttttacat ccttaaactg atatacattg ccgaacaatg tggtctttag tttcataagt
    36061 cgttccctca ggaaggaaat gcgagtgatt tcaccgtcac cggcacaacc gatccgccaa
    36121 aaagaggcgt accaatgtcg atatagtccc ccgcgcggac aatcacttcg tcaatgactg
    36181 ccaacgggag ttgttgtagc tgtgggcgca acaacatgcc cagagcttta ccaaagtcct
    36241 gcccggccac caccagcagg ggatgcggat tcggaaaacg cgcgacgaaa tcgaccaacg
    36301 cgttgatgac cgtcagtacc gcggcgtaac gcacaggcag cgaggcggga agcgccagca
    36361 cgtacgcgtc agttttggga tcaagatcca gctgaatcag cgcctgttgc caggccccca
    36421 ccagatccgt ttcatcaatc gggatcgcca ccggcaaatt gcgcagcggc agttgtacgc
    36481 cctccagcca gattgtgctg ccagagagcg aaagggtatg cgcgcccgcg ccaatcaccg
    36541 tggcgcgcac ggtttgcgcc ggaaactgta cgttcatctc acgcaggcgc ggatggtcat
    36601 gcagcgccgt tgccagaagt gggccaatat cggcaaaaca gaacgggtcg gcgggctggt
    36661 ggcgataaca ttcgcccacg cctccagaaa gcgtaatgat ttcgggcgta acacctgcgg
    36721 gcagcaaacc ggtttgcatc aatgcctgcg cgagcggcga aagcgttccg tcaatcactt
    36781 cgacaatcag cgccgccatc cgccgggtaa cctgcaccag ctgcgcgccg gtcagcgaac
    36841 gggcgtcagt gcctgcaccg aagcactcat ccacaatcat ctgccccggt ttatgagcgt
    36901 aaaccacgcg cccctggctg tcggtttcca gcaggcgacc accgacgttg agacaggcag
    36961 tgccgctgat ttttccggca tcgaacaggg cgtagttcgc ggtgccaccg ccgatgtcga
    37021 tattcagtac ccgacacagc cgttgttcag aaagggtttg cgccccggct ccgtgaccgg
    37081 cgatcacgga ttcgaggtgc ggcccggcgc tggcgacgac aaaatcgccc agcgactgag
    37141 agagcgccat caccgccggg cgagcattgc gggttttcgc gctttcaccg gtgatgatga
    37201 tggcaccaga atcaacgctt tccggcgcaa tgcccgcagc ctgatattgc tctaaaatca
    37261 gcgatttcag ttccgcttct tttaaaccac cctgtttatc gacaggggta aagaacaccg
    37321 ggctttgcca gctaatttcg cgtttgatga attcgtagcg cggcacctgc gacaccgccg
    37381 cacggttaac cagctccagg tgggagaaaa tcacctgggt ggtggtggtg ccgatatcga
    37441 taccgacgct caatagctgg cgagtgttca cgattgtgcc tccgcttcgg ttttagtcgc
    37501 ggtcgcgtct tcttttggca ccagcatcat cgccacgcca atcgccgtta cgccgccgat
    37561 caacttgccg acaatcatcg ggaagatcat ggcgttcatg ttggcagcgg cgaagcctaa
    37621 gtggtcgccc agggcgaaag cagcggaaac ggcgaaggcg cagttgatga ctttgccgcg
    37681 ggtatccatc tgcttcatca tgccgaacat cgggatgttg ttggcaagcg ttgccaccat
    37741 gccggctgcc gcgatgttgt tcatattcag tactttaccg acgctcatca gcggtttttc
    37801 aaaccagcga gtcagcagca gcaccatcgg atacgcccct aacagaacgc aggagataga
    37861 accgataact tcaatggcgc gcatcacctc accgggttta tcgccagggg ccataaagat
    37921 aggatccaga ccggggatca gttcccagcc aagcaggaat ttcactaccg cagcggcaag
    37981 accgagggtg atcaatgcaa cgaggaattt ggcgaagatc tggaagccgt tgatcatttt
    38041 ttccgggatg aatttcagcc ccagcgccac cagaatcgca acaatgatca ccgggatcat
    38101 gttcatcagg atcagggcga aagtgaattc caccggctgg ccgttgatct gcacaccgga
    38161 gtacatagca accagaccac cagcgataca accaatcgga atggtcacaa tgcccgccag
    38221 cacgccgagc gccagataac gacggtcaga aggttcgata atgccgagcg ccaccggaat
    38281 ggaaaacaca atcgttggcc ccatcatcga cccgagaatt aacccagagt atagccacgc
    38341 ggctacgtcg ccgcccgcca gctctttggc gaggaagaag ccgcccatat cgcacgccag
    38401 cagtgttccg gcgaacatcg atgggttagc gccgagcatt tcgtaaaccg gaataattac
    38461 cggcccgaga acgtgagcca gtaccggtgc cagcgcggtc ataccgacca tcgccaggcc
    38521 cagtgcgccc attgccataa agccttcttc gaactgaccg cctgatcctt cgatactttt
    38581 accgaactta ccgaggaaac gagcagaacc gccgaactgc gacaggatcc tgtctacggc
    38641 agctatcagc ataaagaaca tcatgatgta catgatgatt tcgttaattc ccatcgcctt
    38701 tactccctgt tagttgttat ttattggcgg atgcggcgta aacgccttat ccgccctaca
    38761 tgtgcaatcc cgtaggctgg ataagacgcg gcaagcgtcg catccggcaa ttgcaccgcg
    38821 ccactggcgg atgcggcgtg aacgccttat ccgccctaca tgtgcaatcc cgtaggctgg
    38881 ataagatgcg gcaagcgtcg catccggcat ttattgcgcc gctgcgtaca ggccgacaat
    38941 ctgctccagg ctggcggtac gcgggttact gcgcagacaa atatcttcca gcgcggcctg
    39001 cgcccatgcg ccgtaatgcg cagatgtcgc accaacatcg cccagtcgtt taccaatccc
    39061 aacttccgca atcagctcac ttaccgcgtt aatagcgtca cgatcgtcgg attttttagt
    39121 tcgcagtgcc cgaccaatct gactaaagcg ttcacgacaa accatccggt taaattccat
    39181 caccgttggc agcaacatgg cgttcgcgag accgtgcgga atatgcagcg ccgcgcccgg
    39241 ctgatgcgcc atcgcgtggc acaacccaag acccgcactg gaaaacgcca ttcccgccat
    39301 acatgaagcc agtaacatgc tctcgcgcgc ggcaaggtcg tgaccgtagc ccaccgcttt
    39361 cggcagcgat ttgccaatca tcgcaatggc accaatcgcc aggctgtcgg taaacggtgt
    39421 agcgttcagg gcgctgtatg cttcaatggc atgggttaac gcatcaatgc cggtcatcgc
    39481 cgtgacatgc gacggcacac cttcggtcaa tgcggcgtcg aggatcgcca catccggcat
    39541 cagcgaggca tgggctaaca cctgcttgcg cccgctcacc gcgtcgataa tcaccgttac
    39601 attggtggtt tcagagccgg ttccggcggt cgttggaatg gcaatcagcg gcaagcgcgg
    39661 ttgcagaacg ctggtttctg acatctctgc cagcgtgcta tcggggttcg tcaccagcaa
    39721 cgccacggct ttcgccgcat ccagcaccga gccgccgcca aatgcgatca ccccatcaca
    39781 gcctgactca cgcaactgcg ccacggctgc acacacgtcg gtaatgcacg gttcgcccac
    39841 cggacatggc cagagcgtca tggcgatgcc tttaacagcc aggctgcgcg tcagcccggc
    39901 ggtcatcccc gcctgatgca aaaagctgtc tgccatcacg aacagatgtt tcagcccacg
    39961 cgtttgcgct tgctgcccgc aactgctcac cgcgcccgga ccgcaaagcg tcaccggtgg
    40021 aacgctaaat gtttttaccc gttgcagatt cagggtatcg aacgcctgaa agagcgcggt
    40081 ctgcaattca ttttgcatat agcccctccg ctttctctcg cccactactg gcgatcgcca
    40141 gcggggtcat aaacaaactg tgctgcggta aatgcacctg taacgccggg aattgtttgc
    40201 gaaacagttc cgccacgccc ggttgcaaac aagagccgcc cgccagccat aaatcagtaa
    40261 tgccctgccc ttcaatatgc cgggcgacaa tgtccgccat tttttcgtac accggtttca
    40321 ccgcaggcca aatctcttca ccgtgaccgc gcttgtactg ctccgcctct tccagcgaaa
    40381 tacggcgatt tccggcgaga gtcagagaga tgtgatgtcc gccggtggct tcatccgccg
    40441 agtacgtcac cttgcccttt ttcacgatgg caatgccggt agtgccgccg ccgatatcca
    40501 ctacaccggc gttgtccagt tgcagcagat ccgcaactgc ggttggctca tccagcacat
    40561 ggctcacttc cagcccggca gattccagca cgttgatgga aatacgcggg tccgtacctg
    40621 gaggaaatga agtcgccgca tggctaaaac gaagaccgaa ttgctgctca agagtgtcga
    40681 gatggcgacg aacaatggtg acagcgccga agaaatccca gacgatgccg tcgcggacca
    40741 catcggccca gtcgaggcat accgccaccg gctgaccgtc gcggtcgaca accatcgaca
    40801 ccacatcgca ggtgcccaga tccaccccca gccacagcgg ggattccgtc gcggcaggcg
    40861 tctggttaca cagcgttgcc gccgtttgca gacgtggggt gagccattgt tcgtcgtgcg
    40921 ccatcggtta ctccttaaac aatgcgaaac gcatcgacta atacacagcg acgcagacgg
    40981 acaaacgtcc gcgcgctggt taccccttca ccggttggcg tggtgatggt catggtggtc
    41041 cagccttccc cgcccagccc cagcccggca atgcacggtc cgttcttaac gaaaatgctg
    41101 gtatcaatgg cgttcgccat ctggttcatg ttttcgatat tgcgcgagtg cattgccgcc
    41161 gtgtggtggc aaccgccctc cagtttcacc gccagcgcaa tggcatccgc cacgttggcg
    41221 acgcgcacga cgggcagcac cggcatcatc agttcggtca cggcaaatgg atgttctgca
    41281 gtggtttcca caaacagcaa acgcgtttct tgcggcacgt tcaggccgat tgccgccgcg
    41341 attttcgccg catcgcgacc aacccagtca cggctgacgg tgccttttcc gcgctcgtcg
    41401 atatttttca gcaacaccgg ttgcagctgc tgcgcctgtt ctgcggtcag tttcaccgcg
    41461 tgctggcctt ccatcagacg catcagttca tcggctacgc tatcaacaac aatcagtacc
    41521 ttttcgtcgg cacaaatgat gttgttatcg aaagaagcgc ctttgacgat ggactgagcg
    41581 gcacgggcga ggtcagcggt ttcatccacc actaccggcg ggttgccagc gcctgcggca
    41641 atcagacgtt tattggtgtg tttacgcgcc gcttctacta ccgcttcgcc gccggtcacc
    41701 accagcagac cgatacccgg aaacttgaac aagcgttgcg cggtttcgat atccggattt
    41761 gccacagtaa ccagtaagtt ttccggcccg cctgcggcaa caatcgcctg gttgagcagc
    41821 gtgatcgccc gctgggagac ttttttcgcc gccggatgcg gggcaaaaat gacgctgttg
    41881 cccgcggcaa tcaggctgat ggcgttgtta attacggttg ccgccgggtt agtggaaggc
    41941 gtcaccgaag ccaccacgcc ccagggcgcg ttttcaatta aagtcaggcc gttgtcgccc
    42001 gtcagcactt gcggagagag acactcaacg cctggcgtgc cgcgtgcctg agcgacgttt
    42061 ttggcaaatt tatcttcaac gcgacccatg ccggtttcac tgacggcaag ttccgctaaa
    42121 tctctggcgt gtttttcgcc tgcttcacga atggcagcaa tggctaactg gcgcattgcc
    42181 acgcttttta acccttgctg ggcgactttg gctgccgcaa cggcgtcatc cagggacgcg
    42241 aaaacgccca tctcatgaac ggcggcggac ggcgtgtcac tgctttgcat tttcagcagt
    42301 accgctttca ccacctgttc aatatcctgt tgattcatga tgttctgcct tatttgtgga
    42361 aaattacctg accgccagac accacctcat cgacaatgcc aatcacgcac agatcgaccg
    42421 gtgacgtttc gcttttatgc gcctggcggg cggaactgcc actcaccagt aacacccact
    42481 ccccggttcc cgcgccaata ttgtcgatgg cgacggcgca ttgcccgtca ggattaccat
    42541 gtggatcaat catttccacc atcagcaatt tgtcatgcgc cagtccgtga tggcgtacgg
    42601 tacaaacaat ttgtccagtg acgactgcca gtttcatacc cgcctccgtg gcgtatttca
    42661 ggtaaaagct ccccctaccc tccgcagaag gtaaaatgaa aaaggagaga gcgtgacgcc
    42721 cgaatcgacg tcacacaggg tgattacagg ttgctgctat cgcctttcag gccgatcggg
    42781 aacacttctt ccaggtcgcc gtgcggacgc gggataacgt gtacagatac cagctcgccg
    42841 atacgctgtg ccgctgcggc accagcatcg gtcgcggctt tacaggctgc aacatcacca
    42901 cgaaccatgg cagtacacag gccgccgcca atctgcttaa caccaaccaa cttgacgcgc
    42961 gcagctttca ccatcgcgtc agaagcctca atcagtgcaa ccaggccccg ggtttcgatc
    43021 attcctaatg cttccattgt gctttcctct ttatcagggt ccagaacggg accgttcatt
    43081 caaccagtgt ttgtaaactg ctttcacggt ttacttctgt ctgacgcggc acagctgcca
    43141 ccagcgccag ctcgataatt tcctgcacgc tacaaccacg agagagatcg tgcatcggcg
    43201 cggcaagtcc ttgtatcaat ggcccgacgg cacgatatcc gccgagtcgt tgtgcgattt
    43261 tgtagccaat atttccggct tccagcgacg gaaaaaccat cacattggcc ttgccctgta
    43321 gcgggctggc aggcgctttt tgcgccgcca cttccggcac gaaggcggcg tcaaactgca
    43381 actccccatc gactaccagc tttggtgcgc gctcacggac gatttctgtc gcctgctgga
    43441 cattggcaac gcaagggtga cgggcgctac cgttactgga aaacgacagc atcgccacgc
    43501 gcggctcttc tccggtgatg gcgcgccagg tttcggcact ggcaagcgcg atatccgcca
    43561 gctgcgccgc cgtcggctgt ggcaccacgc tgcaatcggc aaagcccaac gccgggccgc
    43621 tgtactgtgg caacatcagg aaaatggaag agagcgtttt acagcctggc tgcaagccga
    43681 taatgcgtaa tccggcacgc agcacatttg ccgtggaaga gaggttgccc gcgatacaga
    43741 catccgcttt accggcgctg accattgctg cggcgaacat cagagggtcg gtaagttttt
    43801 ccagcgcatc cggcggcgtt ttttcgcccg cgcgggccag ccagcgatga gcaaattctt
    43861 cccgcattgc gaggttgcca tgcggatcaa tcacctgtag cccgtccatc gccacgccgt
    43921 gactgagcgc aaactgacga agttcaaacg gattggcgac cagaatgggc gttgccagac
    43981 cttgttgatg taaatattgc gcggctttca gcacacgttg gtctaacgca tccggaaaaa
    44041 ccactctggc gggcgctcgc aacgccagtt cacgacaacg ttcaataatc attgcgtttc
    44101 ccccagtcgt tgttggatct gcttcaccgt tagcggctgc ttcgttacgc tcaggatcat
    44161 catcacgtag accgtgctcg aaaggcggtt cagcgcctgc aaaatgtccg ggcgtaatac
    44221 ttcaaagctg cgggtgataa agacctgcgc cgctacggtt tcggtttccc gcactttggt
    44281 gcgtagcaga ttgagcaacg cagcatcgcg cccgtggctg gcttccggca ccagatgatc
    44341 gtggtcgaga tagcgcagcg gctgatgaga aagccgatgc agatcttcgt cagaaagccc
    44401 gacaatcgcc tggcagccca gcggttcccc cagcgcatcg gcgcgcataa tgttgccaag
    44461 acgcgaacgg atatccgcca gccacggctg ccacggttcc gccagttcaa tttgcagcca
    44521 cactgccagc gcaatggtgc tgtcgagaac cgcgcgaaaa cccagacgcg gatcgctttt
    44581 ggcgaccatt ttttccgccg acaggtgagt cagcgtatcc ggcttttttg ccaccggctg
    44641 gcgacacagt tcgcagcacg cctgcggatg ttcatcgcta ctggtcagcc catgaacggg
    44701 ctgcggctgc tgctgttcat cgtcaacaaa caggcggccc tgctcgtcaa taaacttgat
    44761 gcgcagatgg cggctttcca gcaactcccg ggcagagggc gtcaggcgac tgtccgcagg
    44821 gagatggatc tctgcgcctt cgctgagcgt atggttcgct cttagccatg cttcggtgat
    44881 gaaatctttc atagggattg ccagttagcc ggccaggcga catacaggaa tttcacgctg
    44941 gatgtcgtac caaattcgat actggagcct ttcgggataa acatcacgtc acccgctttg
    45001 gcgatcatgg tttcgccttc gtggcgaaca tgcagctccc cttccagcac catgtcgatt
    45061 tcgtcgtagt tcagggtcca cgggaagaat gcgttctccc actgcataaa accggcggcc
    45121 atgctgctgc cgtcgtctcc ggtcacaaga tcagtcaagc ccacgcaatg cggctctgcg
    45181 ccgtcgaaac gaccaaactt gacgctgctg ccatcaatca ctttgatgcc gcctttgccg
    45241 gtcaccgatt tgaagctcgg ctgcattgcg ccctgctcca gcgactgttt ttccttcatc
    45301 actttttcca tcagctgtgc gaccaggctt tcggtaaact ggccttccgg cagctgggca
    45361 atgatggttt cgcggatgcg ctggctttcg gttttgtcgg ctggcacgct ggcgggcacg
    45421 gacgccgtta ccgggatcga ttcatcacat tcggtgatgg taaaacccag tagatccgcc
    45481 acttcacggg cttccggggt aataatgctg gcgcgcagaa ccacggacat tgcctgttcg
    45541 ccgcgcgcgt gtgcttcacg aatatcattc gctgtgatga gttttttcac ctgcttcctc
    45601 ctgtttggtg agagatgcca gataatccac cagttgctgc acgctttgcg ggtcgtggct
    45661 gtttagctcg aaaatcggct cttcgaaacc cgtctcaagc aataactttc gcgttgcggc
    45721 gacgtcagca tctggcatgt ccgttttact gatgacggcg atttgccgtt tgctgacgcc
    45781 aatatccagc aacccggcag gcaaccgact ttccgggtca tttgcgccat ggacatagat
    45841 cagcatgtct acatcctgta gcgtggtaat taaggcgtga taccagcggg gatggttaaa
    45901 atattcaccc ggcgtatcaa tatcgccctt atcattaaat tccacggcct gtgtttttct
    45961 ggcgagggta taattcccct gcaacgcatt aaataacgtt gtttttcctg ccccgacgct
    46021 acccacaaac gcaattcgtt tcatgaatgc ctcgtattaa cttttggtca tttcacaaag
    46081 cgtataattt aataagcgac ctaaaccgct gacggtttgt gataacgctt cttctactgc
    46141 gcccaccgag ccataaatca ccaatgcacc gctgaatcgg tcgagaaaac cgatatgcac
    46201 atcagcggct ttcagcgcta aatcaccggc gatcatcgcc gtttcgccgg gagttagcgt
    46261 cataatgcca attgcgcccg catccggaac gccgattttc ttcgccagtt cctcaccggg
    46321 atgcgcgatg agatgcgcca gtgtgacctg tttgccgggc acaaattcct gaatgatgcg
    46381 ttctttatcc atgagtcgcc gcctgtgaaa aactttcgtg tatcgtgaca atttttcgtc
    46441 agagtaaata acaaaattcg gcaagcgcgt ttaaaaggtg aggtagatca ctaagaatgg
    46501 agagatattc gctgtggtgc ataaactttc atatgcaacg catga
//
LOCUS       DAPHKZ010000025        43428 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.025, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000025 DAPHKZ010000000
VERSION     DAPHKZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43428
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.025"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            56..1210
                     /locus_tag="RH288_001489"
     CDS             56..1210
                     /locus_tag="RH288_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDV4030559.1"
                     /translation="MPSPRIRKMSLSRALDKYLKTVSVHKKGHQQEFYRSNVIKRYPI
                     ALRNMDEITTVDIATYRDVRLAEINPRTGKPITGNTVRLELALLSSLFNIARVEWGTC
                     RTNPVELVRKPKVSSGRDRRLTSSEERRLSRYFREKNLMLYVIFHLALETAMRQGEIL
                     ALRWEHIDLRHGVAHLPETKNGHSRDVPLSRRARNFLQMMPVNLHGNVFDYTASGFKN
                     AWRIATQRLRIEDLHFHDLRHEAISRFFELGSLNVMEIAAISGHRSMNMLKRYTHLRA
                     WQLVSKLDARRRQTQKVAAWFVPYPAHITTINEENGQKAHRIEIGDFDNLHVTATTKE
                     EAVHRASEVLLRTLAIAAQKGERVPSPGALPVNDPDYIMICPLNPGSTPL"
     gene            1361..2185
                     /locus_tag="RH288_001490"
     CDS             1361..2185
                     /locus_tag="RH288_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001238934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDV4030560.1"
                     /translation="MRLNTTGIAARMMLSLDKKAIGEKLINGRQINPTPLQVRYPQGV
                     REVLGIMSEQLAISTADLTRILLEDALHNMFMPADNTAGNIISRIEYIMLSHDINAPL
                     LATLLSPWNIRSTVIQDPARLADYLSADALEHLAECFNLNPDWLNGHENYPIALSGEW
                     PDTADNFRMLINDSSNTEVIFWHSFPFAGNTKREYYGVILRQKKEINGSVIYPALSLS
                     PTILNDEKRKWLTEYTTRQNTTMSLRRVTLRPGLAGNLITGQILPVSLFNTSLLPW"
     gene            2271..3473
                     /locus_tag="RH288_001491"
     CDS             2271..3473
                     /locus_tag="RH288_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003557916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HDV4030561.1"
                     /translation="MMKKNHITRTIIASAVLFSFNAAAATSYFEARNDAMGGTGVASS
                     HYGVAPLANPALLTKHNSNDDFSLLLPSVGAQVADPDDVSNKADDVKDDWDLFDSAVD
                     NQHGVQQAAANLKHRLQEFRNINADAQVGVSAVAAMANDTLPFALMVKSYGTVSVNGK
                     VNDADLDYLDKVANGTITDVDKNALTSRAFGRAAVITDVGISFAKELETAGQKWSLGV
                     TPKYQRVDLFNYNVTVRDYDKDDFDGDKYHNTKNGFNADIGAYTDLNDNWTVGLVAQN
                     IIPRSIDTKVVNGFKETFKVRPQATAGVSWHNDLFTTALDVDLTPASGFTSDSKRQFA
                     SVGAEFNAWKWAQLRAGYRQNMASNSGSAFTAGVGISPFDVVHIDVSGLVGTDHDYGA
                     MAQLQFTF"
     gene            3533..4117
                     /locus_tag="RH288_001492"
     CDS             3533..4117
                     /locus_tag="RH288_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDV4030562.1"
                     /translation="MMKPRSSYSKTAFILLFSVFLVAAVTKAKSSLPDITLEQAKEIN
                     ADNTVIFLFRHGEHCDRSDMPCYSDKSGITITGTEKAQQEGIKFATIFSEYDIYSSNA
                     VRTIQTAKFFSGKEPVVMDSLSDCNNDLYKTLESIARESHKRNIVIMTHNHCLSFLAR
                     DRLGKKFKPAYLDALIMHYDGTRLILDGKYNKEA"
     gene            4512..4970
                     /gene="traH"
                     /locus_tag="RH288_001493"
     CDS             4512..4970
                     /gene="traH"
                     /locus_tag="RH288_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer lipoprotein TraH"
                     /protein_id="HDV4030563.1"
                     /translation="MNRIIPAGCLAALFLAGCNSPSQHTPVPRNYGAASDVAVTRHTQ
                     YTLWDKGVFSGQLPVSTGSHLLTANSDRLSFDWEGDAIELLNELARVRGMQFNYNGVR
                     LPLPVNLHVRDMTFSNTLRLIEAQTAWRATIHQYPGLLQVSFMQPENRKK"
     gene            4967..5785
                     /gene="traI"
                     /locus_tag="RH288_001494"
     CDS             4967..5785
                     /gene="traI"
                     /locus_tag="RH288_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer lipoprotein TraI"
                     /protein_id="HDV4030564.1"
                     /translation="MKALTSLILPVILLTGCSSSPTISPGGVNTPPPDINAWLKPRSE
                     KPDSLSETRWKMLTDAGKTLGFRGGKAQRSWELIQALNARESTLNALYDFRPLISPEG
                     WLPPVIDEAQDVAHITPDQIRTSSRVWTIIRPERFVSNPPGWRDWLLRGLSTTATPGT
                     EGSVVPEDSVQRKVWETALRQGWQEGRQNADLTLEANQKTLTRDYRGMMLYSLLWRQG
                     MITRPDVSDQMQTVTGDGKKLVTGDRVRRLKNHAEFNLQKSHWRPLIGTEGGSR"
     gene            5782..6930
                     /gene="traJ"
                     /locus_tag="RH288_001495"
     CDS             5782..6930
                     /gene="traJ"
                     /locus_tag="RH288_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid transfer ATPase TraJ"
                     /protein_id="HDV4030565.1"
                     /translation="MNIPDEFGLFPFQRFTADELRHFFVWCAAHKVSDVDLTGGSPVS
                     VSRFGRRVRCSSATLPTTLMSSLIDELFGREVIPRVLAGNPVDRTIQINGDASGRYGL
                     KRGERIRLRSHLIQGTSGAEEKAISITMRVIPTEIPDILSMNIEPDLLEAMVCKSGLG
                     FVCGETGSGKSTLCSALYRYIMDNFPDAKIVTYEDPVEYILGNENDLLPPHQAEIGRD
                     VVSFAAGLRSAVRRNPEIIGVGEIRDNETADAAVQAGNTGHYCLSTMHTKSPGETLAR
                     LLGLFPPVIRDSMAWAVLSLLQFILVQVLVRTNDGGRKAVREYIVINDELRDNLSGMP
                     HAEWGHHIDAIIRQEKRRIRDQILEMYIRNEVDRREAILFIPPGELRS"
     gene            6927..7217
                     /locus_tag="RH288_001496"
     CDS             6927..7217
                     /locus_tag="RH288_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDV4030566.1"
                     /translation="MKREGFWRYATPPVNIQGVPLPFTMIYLFICPFPSKTTFWICTG
                     IILFFVILDRSGWTVRTICTRIFSILRGAIASGRPWWYRHHTESPRDWTGLD"
     gene            7232..7783
                     /locus_tag="RH288_001497"
     CDS             7232..7783
                     /locus_tag="RH288_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HDV4030567.1"
                     /translation="MSGKKTIVTLLRVSLLACPLLFTTPSFAMIDTPSVKVGFSPEGS
                     ASALVLDTINSAESSIRMMAYSFTDPDVMHALAKAKKRGVDVRIVVDDKGNTNRASQE
                     AMKYINLLDIPLRTVDAFPIHHDKVIIVDGNTVETGSYNFSRAAARKNSENVVVLKNM
                     PDVAAQYLEHWQDRWNKGTDWRP"
     gene            7873..11640
                     /locus_tag="RH288_001498"
     CDS             7873..11640
                     /locus_tag="RH288_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDV4030568.1"
                     /translation="MPSVSRYRTWLAVPADEIEDLKKAHPPMNGHTPVIWDKEHKLWF
                     ARPGADLSRLDRWLPRPQDVSMNGSDPVTEFAQVLENAGLVLKELPVMDGKIHRVPTA
                     DDKKGQKSGAYRGFLDGRPAGWYRDYRSADNSPITWTFSGGEQTDPRARLHLKAHSMQ
                     RREDAERELKAQYNRQAAYARRYINKWPQATAHEYLTRKGIQAAPGVRVNNKNELVIP
                     FSNRNGAIRSYQRIPVTGGKDARILIDSEKTGNWFALGTPRNGQPVLFAEGYATAASL
                     HEATGLPVLMTVDGGNMIAVAENARQKWTQSPFIFCADNDHAIRVNKGIVSATKAAEL
                     TGGSVIFPAFTDAEKAQGLTDFNDLDASRGRAAFQHVINAQLEHIGVSTPNSNTPEMR
                     EALVIGNLVFTPVHTEEKTMTPTEYPETSPDTGHSHDQGPSLPSATQQEQPAASSSNI
                     ADETQSFTSHATENNGKDERHADNVQAQTESSVVQDSPAESPASPESTTASAPDEPAH
                     PAEPPEKVVSVATDKDWREFEAELSQPEKNESQQESGTSPEIPAPAATPASPEDSPSS
                     ETMNESAEPSPSPDAVKEEMTVMTEPDDKQSTGISPDTPREEAVNHVTEDIPLQPEPF
                     LPESDGPEEYENYSAYQELMNNENPEHLQENSDMPSQPDTGHVQADESELQATTDTVE
                     PAVRDDPTPQQPVQSTSSSDNTSSFLDKARGFFTRKKTDSQAHENSDPTPSPETTTTT
                     PAPDSIVYAPERPDVPISLNLDEIIKSLEGEERADRTVLYKLDGKPAFIDRVNRLEMV
                     NGASNDDRSVLAALAVATDFYGGVIELTGSDAFKQKAMQLIIEHNIKVRMKFPDQRAA
                     LEKLRKEMAVGKDTVVTHKPTPELNRNTPEQPAVPDPVKEKEATQSPASPVAPEASTV
                     STVPASSPAEPGKTADAAQGEEPPGKLRPGESVTAVLHNFGRAEYAPGKGESFFVELK
                     NRSGSKLYWGEQLESLVKNHQKGDVVTLTLQNREQFILPGEQKARFRNKWSMESVTNG
                     ISVSHDNPDKGQRIQAIPVETFMKVAAQISQGWPEEMKALRMPENVGSHLFIGEDRHP
                     VSAPQNANQVTEITSAAPDKLTPVLGSVDKDTRELNLLLVQSADEHLQGVVRLNGTLY
                     PALATPSADNSQLVINALTDKGLRFAGYGEAVNHDADSTNRPAPELMQFHLKTREEPL
                     FAAVYTPEKQPDALYRNLGFEQSWQQWSNSQKPEDRQEKTLHQDLSHSPGR"
     gene            11658..12005
                     /locus_tag="RH288_001499"
     CDS             11658..12005
                     /locus_tag="RH288_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001629514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDV4030569.1"
                     /translation="MNMHKSLVAVLGLILISSTASAATCRAGSAAQAGSNTGYERARA
                     AADAWSQRENDVSSSLQSCLSRIKKISINLPQFPSLDDILSQLENQVCDAVVDKVNEK
                     LPGNIDPWKDYNL"
     gene            12002..12694
                     /locus_tag="RH288_001500"
     CDS             12002..12694
                     /locus_tag="RH288_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotI/IcmL family type IV secretion protein"
                     /protein_id="HDV4030570.1"
                     /translation="MTENTEPSSPSHPAPDPEILKSTIRAMKQSEQRANNVPALIKAL
                     LCTGTCLLISITGNAIQYWHSTNVEREYFATDNGRLVRLAPTSQPAWSQNDAMAFGSQ
                     ALATAFNLDFVHYRSQISSLSPRFSDEGFVGYVNALQASNILETIKKEKMNLTATTGA
                     GVLVRQGQMSDGVWFWTFQYPVRMRLVGQTTSKPEQSFVFEITIQRVDPRLKPSGMEI
                     RQMISRNAGPNS"
     gene            12705..13688
                     /gene="traN"
                     /locus_tag="RH288_001501"
     CDS             12705..13688
                     /gene="traN"
                     /locus_tag="RH288_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001191879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraN"
                     /protein_id="HDV4030571.1"
                     /translation="MQSRYLLSTLLLVCSAATSADNAGWQNARTPQTTNSASDHVQNA
                     SQNTGGVPATLVKGELPAPGQASPLVQDAARLDSELSADEIRSLRSLMADNERAINAP
                     ITSVVPRISSLTVNLSPGASLPLVRTAMNNLSVVTFTDINGSPWPQSDPPYNAAPKLF
                     DVQYNENMVTITPLRPWASGNISVYLKGLSVPVILNVTSGETDTPSSSQEMDSRLDLR
                     IPRQGPTSPVVSIPTDKIALHDATLQAFLDGIPPRDPSVKRLKFTGNVPDTTIWQHGD
                     DLLVRSRAMLRDEFEQTLSSADGTHLWKLPVTPLLTFSVNGQSIHVTPELE"
     gene            13691..14980
                     /gene="traO"
                     /locus_tag="RH288_001502"
     CDS             13691..14980
                     /gene="traO"
                     /locus_tag="RH288_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraO"
                     /protein_id="HDV4030572.1"
                     /translation="MSAEQDAGKSGKKLAALLGLGSIILFGGGYIAFSKLSGSNSDMQ
                     SAVNINSAASGGTRSVTETPHYRELLRADNERGAAAAARNNQTFIASLPQGLDIPDTQ
                     EKQQQPAAKPENYAHRQASGTPQEDRAASEKRMERLQKLIVRIKDQHPAGSTPTIATT
                     MWNKSPAETTGQNGTQQFALKNASLSTPVAEKGIQLIPALTRIPAYIDTAVDSDNPSS
                     KVIATIPAGPWAGATLFSPGVKLVGNGVEIHFDRMSWNGMDLKVNAYAQREDNLMSSV
                     ASNVNTRWFKHIILPSVLGGVGSIGTLYKDANTQVIQGNYGTVTGRVGMPSGEAVAGV
                     IAGGMAERGSQILTRQAESEPYKQVEVYQHEVVSILFVDPVMTNDARSSSLSSGISPS
                     VNRTSQAEQRSQARMQTAMEQRKAVMQRRYDEQPETP"
     gene            14980..15684
                     /gene="traP"
                     /locus_tag="RH288_001503"
     CDS             14980..15684
                     /gene="traP"
                     /locus_tag="RH288_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraP"
                     /protein_id="HDV4030573.1"
                     /translation="MKPETEIDETGSFGEPEEKPAPFWKRSVWGISVATWGLCAVVLL
                     AAIWYLFLRAPSETGMPPFNDADAGVQTWQTTQESSPSVQSTETMTVRTGEDMSQLAR
                     DVKTELDNRDEKIQATLNMLHDSINKLGEAIKKDEEYAQETRRQLDDIRSRLNGIMTQ
                     KSVTESSSTPHPAKKKTSSVLNGMKIMSMETGMAWIRWQGSTWAVREGQTLGNVVIQR
                     IDPTTRTIITSAGTLR"
     gene            15684..16211
                     /gene="traQ"
                     /locus_tag="RH288_001504"
     CDS             15684..16211
                     /gene="traQ"
                     /locus_tag="RH288_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraQ"
                     /protein_id="HDV4030574.1"
                     /translation="MNMDALTAIENFASSIFSAGMDFLFTWGEFIGVISMITLFARAR
                     SAGPVKMSPGKFIAGMLTSCMLVSLPAMINAGGVQMGFRADSFGPIAYVQPQTFGAAA
                     GAANAVLSLAKLAGVGFVMNGISIWRKAGLDGHTALSASESVSKGNVKFIAGVLLVFI
                     DRVLNALLASIGIVF"
     gene            16262..16666
                     /gene="traR"
                     /locus_tag="RH288_001505"
     CDS             16262..16666
                     /gene="traR"
                     /locus_tag="RH288_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraR"
                     /protein_id="HDV4030575.1"
                     /translation="MSRIRVVAARLYAAFIHAQLFVMSCRSKLTKFLLLIPMMLLPKA
                     VLADGDLADMVRNVEQGAKTAQSSSLTIAQFIGVILFLGGLIGLKKVGKQGGMGLASC
                     IVSIVIGAVLVAGPEMMSRSQKQLGISSISIG"
     gene            16730..16918
                     /gene="traS"
                     /locus_tag="RH288_001506"
     CDS             16730..16918
                     /gene="traS"
                     /locus_tag="RH288_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conjugal transfer protein TraS"
                     /protein_id="HDV4030576.1"
                     /translation="MSAWSPEHITLRRTENGNVIAHDSRDDQEFIFAECCSDEIANII
                     LEAVKRYTSTEPAHATQH"
     gene            16902..17702
                     /gene="traT"
                     /locus_tag="RH288_001507"
     CDS             16902..17702
                     /gene="traT"
                     /locus_tag="RH288_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001164783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraT"
                     /protein_id="HDV4030577.1"
                     /translation="MQHSIKDLWLYPFPEIDVVHTQEPLLPEPELTTPGRCICCRQNV
                     RHRFRLDDSWPLRQLTDTISDTRVRLNKATEHLDKLKKRGEPVATGEKEKYNTAVKAA
                     ERALEQARLSARRLSLRHVQKAEITSTESLSEKEQELFHEDGPPYSLCAFCHAWHSLN
                     GYAAAQGVMVWLPDLHPSTVVALNRRSLQEVFSNDKFRVRRGREALSALMQNRLAVED
                     KFRSFRPADFADVFRRYPPSGRSPLREKMNGIALILTPDSFIKKEYVD"
     gene            17792..20836
                     /gene="traU"
                     /locus_tag="RH288_001508"
     CDS             17792..20836
                     /gene="traU"
                     /locus_tag="RH288_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraU"
                     /protein_id="HDV4030578.1"
                     /translation="MNINRFIFTIEDCLNTLSRFSVASSFVEYCDLRTVIGLDRQDRE
                     RRPWLNSPYIAATKRGEYLSVFEVSGAFKEMDEASDQTGPGSLESLITSMSDSLNTAY
                     KNSGHKISCVFERDPEMGKEEIEDMVAPQKRSLANTGIQLQDVVDEKVTTLSPWLVRE
                     RCWLAIWSGPDLISNSDRTAHDELVRRLAERVPKARFAQSPWQWTLSALKIRHEAFLD
                     NVEQALRHSSDGLILRLLDIHEVGREIRRQTERYSTPRNWQPHLPEDAQPAGYRWTDD
                     ESVLHAPSLHLQLFNTQVTTQGNLVQAGGLWHGMVSITLPPQNLQTFNELVRAVPRAV
                     PWRIRMDLMPGGMKALNLKKTLLTYSSFISAVRPMYESVMTLAATDEKEPVCIMTIMA
                     STWGKTREICARNQAILKSAIEGWGVCGTTTTFGDPRRAWVNTILAASGGSGPVPLYP
                     PLSHAISLFPLNRAGSVWRGKGNLMLHTEDGSAFEVGLASSQQNKHTELAPGDPGLGK
                     SVLINTLSEIQISSAQKNLPFIAYIDKGYSAQGLVQLIRDSLPPERKDEAVGIILSND
                     PEYTRNLFDVMYGAKKPITPEKNFMSSVLCALCVDTGTGQPCNPGDTRQIINQLIELA
                     FKEYGENNPRLYRASTEELVDSALQDSGLYEKHDAAWWARSTWFEVRDMLHNAGYIMA
                     AQRAHYQAMPQLPEVSSMLGHTSLRDVFGTVQRDGSNELLLDYIRRALEQGHNDYPMI
                     SGYTRFMINPETRVIAVDLNNVAGDKTPAGRLKTGIMYLLAGQIAGGDFTLPQYRDEV
                     LKQLPREYHEIALKRINQLDQEVKTKVYDELHNARGIDFIWENLDTQEREQRKFAIRT
                     VLSTQYLRDYPESVLKSANTLWLIRYKPEDIPVLRDNFNVPEFMLKRFLKMPEGPAPD
                     GSGVPVLGVFRVKSGTLARILKFTVGPLELWALNSSPKDSALRKTLTNKLGSVRARKI
                     LAENFPRGSATSLIEHRAGQHNSDNVIEDLASELIRKQGYNL"
     gene            20836..21450
                     /gene="traV"
                     /locus_tag="RH288_001509"
     CDS             20836..21450
                     /gene="traV"
                     /locus_tag="RH288_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraV"
                     /protein_id="HDV4030579.1"
                     /translation="MCTIHITPRCRRPARGQVFLKKLEVKGDSFSFTLPSRLFRLHPA
                     PNPRVIYASDARTQGKVTGMRLLLPSSTDELITTAIWQVSVPDEAPFDVQHVIQWILP
                     SPLASLMSDDTWLWPSVPGTPALSAGDWPVMDTDPSTLRRVRRRSFSIIDNRNRKGYI
                     TRRYQCFPLAPLPEDRKYDSLPDLVLHPEQETIKCKEKHYSQPL"
     gene            21417..22619
                     /gene="traW"
                     /locus_tag="RH288_001510"
     CDS             21417..22619
                     /gene="traW"
                     /locus_tag="RH288_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraW"
                     /protein_id="HDV4030580.1"
                     /translation="MQRKTLLAALIAILSGTACQAHAYSVTVVASRPVEQQVVPRMEA
                     IKGVLSDILSTQTATGTAINQNSEKLASVIAQNGQATRQQMIFSNETQRLEEARKSFT
                     VPDSICSESASGIATESKSASASAASKLSKGGGVSNRNIRDRLASAANSPVREAYDGA
                     AIHASYCTEAEYARFGGTAVCPSVGEIPGGDSQVRSIYHGAGTADTPAALTWDQKQID
                     AATAYMKNTSRPSAGRALGKGEVNTQSGRTYVGLQNEYNGIIDSASNPQLTLIADSTP
                     NESTRKALAETLQSDSAAAYFDQVASPEAKARGYMSTREFEAFEAGRRYANTAYLVDL
                     QEMQGDNLLRELVRITAQMNWQLNDLKEQIRQGNVISGQQLALTARQYYEKQLGSLEK
                     TINQANAR"
     gene            22648..23232
                     /gene="traX"
                     /locus_tag="RH288_001511"
     CDS             22648..23232
                     /gene="traX"
                     /locus_tag="RH288_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDV4030581.1"
                     /translation="MNKLPENSDQTKNVKKSPSITRIATRRIINIFVPLMETRLITNS
                     VQHMLKQQKSRLEKFRQVNNKKAQLCLSWEEALLASHMSVDDLDRRFRRRRTAWRLCC
                     WSLLAIALFLSGMLFAASSLPLMTLVRAISTLMLILSGVALCASRALIVTYRLWQLHE
                     RKVSEPEQGTFRDFLNDRNGWRNATLIAVTSKQY"
     gene            23329..25497
                     /locus_tag="RH288_001512"
     CDS             23329..25497
                     /locus_tag="RH288_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotA/TraY family protein"
                     /protein_id="HDV4030582.1"
                     /translation="MKILLRALCAGLAISSLPAMASVTYQDIVSAATNPDDLSRQALV
                     TIFGDVVTNPLSTSDPTLIGSMFWVFNNIIAVLAIVWCIFISIRHVVRSGHQGQVFSV
                     GRDIVGILSFVAGFLMIVPTGNGWSLAQLIMLWGASIMGVGSANVMVQVAADNIANGY
                     SMTVQPVQASTRTAARGIFEMELCKYAVNAGLNDFNQTAKSSTSLMTESAKTASGNYT
                     VTVSNGSGICGTASLSVEGNGTTDQSTIGKFFNPFSKNEYSGVISAQRAAMDNMISDM
                     DNAASEFVTTFLEKRNSGNGTLPDIETRIQKAADEYERAVQKSLPTDNGEQSRKEALK
                     SYLTTYGWVTLGAWYQTFATANQRLAELADRAPAVTSMSSLGEVGDTDLFSAVMSAYR
                     TQLQNSSYTPPLGTVVSSSEQRMANAQDPKSALSEIMGPLVSLTNRIATETSGTGTTS
                     AQINPLIKMKNIGDITMVSAEGIWTIYTTARVVVAGGKDSILVKFFNSLTGAASMLTA
                     LFEALAPPVYFLLFLMFCAGFSLSIYLPFIPFIFWMTGIGNWIVSVLIGCTAGPLWAA
                     THLGTSEDRGSRAAYGYIYLIDSMIRPPIMVFGFFFASVAIIAVGTILNALFGAALVN
                     VQFNSLTGIFSLAGFLLIYARICTTTVAAIFALQAYLPDHVINFLGGRDGANTLGSMA
                     NSVKEIFIGGSRNIRHTPGMKTDRLKDNTKGSDDKDGIKG"
     gene            25568..26230
                     /gene="excA"
                     /locus_tag="RH288_001513"
     CDS             25568..26230
                     /gene="excA"
                     /locus_tag="RH288_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid IncI1-type surface exclusion protein
                     ExcA"
                     /protein_id="HDV4030583.1"
                     /translation="MKAKKETTDRFPTWWLFYYVLRKAYFFLGIPFFLFCALGFTEML
                     CSDRYFGNKVEDYVVTFGSWFLLLAPGIWMYSRAKTRREKIRKVVQTIKESGFYSPEK
                     GYEGLSLTQGAYFGIDLKNGTMLYVRIYPGNIMDVIGFDIHNFTRTVTDDKKLEIHTK
                     YINLPMVPVPSWCAHPETASNTMHAMASRGYDYPVDFPRLIQEKRKEWEQIAGMPVAE
                     VF"
     gene            complement(26302..26511)
                     /locus_tag="RH288_001514"
     CDS             complement(26302..26511)
                     /locus_tag="RH288_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDV4030584.1"
                     /translation="MSMPPAIANTFLFEMMKSKSKDVTLAAIYALGEGRCQAENITRE
                     LHRLSQSDDMEIKIAAIKALGRIYR"
     gene            26903..27079
                     /locus_tag="RH288_001515"
     CDS             26903..27079
                     /locus_tag="RH288_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030585.1"
                     /translation="MNLVDAFVKKVISGPYEEYGKWWIDVEYISWGVPGKTRLMFESK
                     EQALEVKEGYKFLT"
     gene            27800..28822
                     /gene="istA"
                     /locus_tag="RH288_001516"
     CDS             27800..28822
                     /gene="istA"
                     /locus_tag="RH288_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100 family transposase"
                     /protein_id="HDV4030586.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEP
                     PKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDLGYRGGMTILRAFIR
                     SLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMR
                     YDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFS
                     PRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVA
                     NQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNFDKHPLHHPLSIYDS
                     FCRGVA"
     gene            28822..29601
                     /gene="istB"
                     /locus_tag="RH288_001517"
     CDS             28822..29601
                     /gene="istB"
                     /locus_tag="RH288_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
                     /protein_id="HDV4030587.1"
                     /translation="MMELQHQRLMVLAGQLQLESLISAAPALSQQAVDQEWSYMDFLE
                     HLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERN
                     ENIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQR
                     GVMAPRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDA
                     ALTSAMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE"
     gene            29962..30213
                     /locus_tag="RH288_001518"
     CDS             29962..30213
                     /locus_tag="RH288_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030588.1"
                     /translation="MSEKWSKEFDSCFQVGSIEEIADALEKRSGSEENALAMLAMTAF
                     TLMTRRGICEMQNVAPDGKGIRLELIGFRGNETIPDTLH"
     gene            complement(30285..30437)
                     /locus_tag="RH288_001519"
     CDS             complement(30285..30437)
                     /locus_tag="RH288_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001618166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HDV4030589.1"
                     /translation="MPQRTFLMMLIVICVTILCFVWMVRDSLCVLRLQQGNTVLVATL
                     AYEVKR"
     gene            30729..31937
                     /gene="trbA"
                     /locus_tag="RH288_001520"
     CDS             30729..31937
                     /gene="trbA"
                     /locus_tag="RH288_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TrbA"
                     /protein_id="HDV4030590.1"
                     /translation="MSYNRQPVAEDPMQIWGAVGVLLILLLFVIWLFLPEVVYASCLI
                     LHTLWGLVDWGPFHNYAAPRYNLLAMTGNNAANISYSQWVNVMEQTIGILWMYLLPVT
                     LWCLWEWYQHPGQSRFTRRPVDITRLPHIFASLSPAIAPVLADGDPEKLFHGGKRPER
                     RVALTPEAFVEQHTLITNMQLDVAAARRCFMAQLGKPLTSWKDMAPHEKALFAIFGLQ
                     YFLDDRKAALKLMDTLNLSCRIKSKRDSGKFCTPVYSLAKSAFQRVIKSNGAQQWLKQ
                     HRYVRSGLVWLYAHDLRLTPPNWIWLKGVDRTLFYALHRANTTKGFIEGAGVVAVARA
                     EAEAMRFGLPCPEPCVDEAVEGLRRDMLSLGLIWDEPQPDRDRKRRILTNWSLTDDIL
                     PRTPATDNEF"
     gene            31956..33026
                     /gene="trbB"
                     /locus_tag="RH288_001521"
     CDS             31956..33026
                     /gene="trbB"
                     /locus_tag="RH288_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TrbB"
                     /protein_id="HDV4030591.1"
                     /translation="MTIEYFATRIAKHISVQAIWPDGRTEIIAVLPRDALSGLVTRNN
                     QLIHIAFDAMGTRNKETVLIDKQEHNADQILTAIDSCLRLEYLMERRFSRTPLFRGII
                     ASVVLFVMATIGFSLFRYVDRVFWDDTTPEAVQTAGEPRLLPPHLNHTVPLNEGIQLP
                     VPPKKDVQVPEKTITSKNPEAAAARHNLATVLKRNADRGMFTINLSSGHERTLFAFLD
                     PACPNCRLLEPALKRLASDFNVVIYPVSVIGGEESTDRVAPLLCEKDAQKRAAGWHRL
                     YSADNGMMTPSEETTPADETCLKAARAAIDVNNVAFRKFGFAGTPWVLSDTGWHLPTG
                     ILQETGTLNLFLKTTDSESDHE"
     gene            33019..35310
                     /locus_tag="RH288_001522"
     CDS             33019..35310
                     /locus_tag="RH288_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbC"
                     /protein_id="HDV4030592.1"
                     /translation="MSEHRVNPELLHRTAWGNPVWNALQSLNIYGFCLVASLVASFIW
                     PLALPACLLFTLITMLVFSLQRWRCPLRMPMTLECADPSQDRMIKRSLFSFWPTLFQY
                     EVILESPASGIFYVGYQRVRDIGRELWLSMDDLTRHIMFFATTGGGKTETIFAWAINP
                     LCWARGFTLVDGKAQNDTARTIWYLARRFGREDDVEVINFMNGGKSRSEIILSGEKTR
                     PQSNTWNPFCYSTEAFTAETMQSMLPQNVQGGEWQSRAIAMNKALVFGTKFWCVREGK
                     TMSLQMLREHMTLEGMAKLYCRGLDDQWPEEAIAPLRNYLQDVPGFDLSLVRTPSAWT
                     EEPRKQHAYLSGQFSETFSTFTEAFGDIFAEDSGDIDIRDSIHSDRILMVMIPALDTS
                     AHTTSALGRMFITQKSMILARDLGYRLEGTDSDALEVKKYKGRFPYLCFLDEVGAYYT
                     DRIAVEATQVRSLDFALILMAQDQERIEGQTTATNTATLMQNTGTKFAGRIVSEGSTA
                     RTLKSAAGEEARARMNNLQRQDGIFGESWIDSPQISILMESKIDVQELIELHPGEFFS
                     IFRGETVPSASFFIPDNEKSCSSDPVVINRYISVDAPRLDRLRRLVPRTAQRRIPSPE
                     NVSAIIGVLTAKPSRKRRKIRTEPHTIVDTFQQRIAGRQAAMAMLEEYDTDINARESA
                     LWETAVNTLKTTTREERRIRYITLNRPELPETKEENQISVRAERAGINLLTLPQDNNH
                     LTGRPVNGFHHKKTNRPDWDGMY"
     gene            complement(35347..38046)
                     /gene="nikB"
                     /locus_tag="RH288_001523"
     CDS             complement(35347..38046)
                     /gene="nikB"
                     /locus_tag="RH288_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type relaxase NikB"
                     /protein_id="HDV4030593.1"
                     /translation="MNAVIPKKRRDGKSSFEDLVSYVSVRDDMTDEELNLSSSSQAEQ
                     PHRSRFSRLVDYATRLRNESFVALVDVMKDGCEWVNFYGVTCFHNCTSLETAAADMEY
                     IAQQAHYAKDNTDPVFHYILSWQAHESPRPEQIYDSVRHTLKSLGLGEHQYVSAVHTD
                     TDNLHVHVAVNRVHPVTGYLNCLSWSQEKLSRACRELELKHGFAPDNGCWVHAPGNRI
                     VRKTAVERDRQNAWTRGKKQTFREYVAQTAVAGLRSEPVHDWLSLHRRLAEDGLYLSQ
                     MDGKFLVMDGWDRNREGVQLDSFGPSWCAEKLMKKMGDYTPVPKDIFSQVEAPGRYNP
                     DFIAADVRPEKIAETESLQQYACRHLGERLPEMAREGRLENCQAIHRTLAEAGLWMRV
                     QHGHLVICDGYDHNQTPVRADSVWSLLTLDNVNQLDGGWQPVPTDIFLQVTPTERFRG
                     RRMESCPATDKEWHRMRTGTGPQGAIKRELFSDKESLWGYSISHCSPQIEEMITQGEF
                     TWQRCHELFAQQGLMLQKQHHGLVVVDAFNHEQTPVKASSIHPDLTLGRAEPQAGPFV
                     SAPADLFDRVQPESRYNPELAVSDRYGVSSKRDPMLRRQRREARAEARADLRARYLAW
                     REQWRKPDLRYGERCREIHQACRLRKSHIRAQYDDPALRKLHYHIAEVQRMQALIRLK
                     EDIRDERQKLIADGKWYPPSYRQWVEIQAAQGDRAAVSQLRGWDYRDRRKDKSRTTTT
                     DRCVVLCEPGGTPVYGNTGDLEARLQKNGSVRFRDRRTGEFVCTDYGDRVVFRNHHDR
                     NALADKLDLIAPVLFGRDPRMGFEPEGNDKQFNQVFAEMVAWHNVTGRTGHEDYRITR
                     PDVDHHREGSERYYRDYIAANSNDDASLPPPEQDKRWEPPSPG"
     gene            complement(38057..38389)
                     /gene="nikA"
                     /locus_tag="RH288_001524"
     CDS             complement(38057..38389)
                     /gene="nikA"
                     /locus_tag="RH288_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type relaxosome accessory protein NikA"
                     /protein_id="HDV4030594.1"
                     /translation="MSDSAVRKKSEVRQKTVVRTLRFSPVEDETIRKKAEDSGLTVSA
                     YIRNAALNKRINSRTDDAFLKELMRLGRMQKHLFVQGKRTGDKEYAEVLVAITELTNT
                     LRKQLMEG"
     gene            38623..38958
                     /locus_tag="RH288_001525"
     CDS             38623..38958
                     /locus_tag="RH288_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobC"
                     /protein_id="HDV4030595.1"
                     /translation="MASKKFYSDDDIQLAKAALSELPDLTAQRKTLRDFLDAIRDDII
                     VLIRTKGYTLADVRDTLKNAGYEVGEKALRDIIREAESKKPSRRSSSKTAPKKTDSGR
                     KDGIDMNNN"
     gene            complement(39044..39892)
                     /locus_tag="RH288_001526"
     CDS             complement(39044..39892)
                     /locus_tag="RH288_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HDV4030596.1"
                     /translation="MNQTLPTADLNTAGTTDVIPSVAIDRIIAQRNEGIALFMQAMEC
                     LATARKILLDASGDIFLYGFEDCVTDSVRRIDKPEEAKRNITRLADRKIWERLMTDTG
                     MYTFMSSCQRDEWNSQLMSDTCPEITLDNVLATFRHLNACKMQTFEQGLIDVYRKLSW
                     DYRTNNPCRLGKKIIIENLLYRWSNGRVTLDCSGREALDDLVRPFYLLEGRNVPDFRN
                     SIGAQYGEFLGNGDNVGKLLEGEYFTVRGYQKGTVHIVFNRSDLVEKLNDIIARHYPG
                     VLPPRV"
     gene            40473..40724
                     /locus_tag="RH288_001527"
     CDS             40473..40724
                     /locus_tag="RH288_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV4030597.1"
                     /translation="MTGWELRIWRKSMLWSREKAAREFGVTQRTWHAWENAEQVDVTV
                     WRTTQALSVRDLLPHMQGMRKADIIRRLENELGETAGNV"
     gene            complement(40755..41036)
                     /locus_tag="RH288_001528"
     CDS             complement(40755..41036)
                     /locus_tag="RH288_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014358130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030598.1"
                     /translation="MRTAKPGKIPGFFASRSRENSMTLAERLIQKGFDEGFKEGFKEG
                     FKEGFKKGALEVAREAACRLRDMGWTPERIQEATGLSGEELKKLFPDEQ"
     gene            complement(41036..41938)
                     /locus_tag="RH288_001529"
     CDS             complement(41036..41938)
                     /locus_tag="RH288_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012548938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDV4030599.1"
                     /translation="MSKKKTTTTPTPHDAAFRSFLANPDVARDFLELHLPAEYRQLCD
                     LSTLKLEPATFVEPDLHQYASDILWSVKTTGGEDGYVYTLIEHQSTENLYMPFRMLRY
                     SVAAMQRHLEQHKTLPLVIPVLFYHGERSPYPYSMNWLDCFENPALAAKIYTNPFPLV
                     DITVVDDNEIMNHRRMAALTLLMKHIRHRDMMELLDKLPQVMVEISDEQVRVLIHYIV
                     NAGDSVSPEFMRALAERLPQHEDKLMTIAERLEQKGRQEGRMEGALEKALAIACQLQK
                     MGMTPEQIKQATGLSDDELKKITH"
     gene            complement(42003..42269)
                     /locus_tag="RH288_001530"
     CDS             complement(42003..42269)
                     /locus_tag="RH288_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030600.1"
                     /translation="MRPSIIFATAEYVKRLREECLRENKPLHRHTRFRRQELAQDEIN
                     PDVLAMSGHIARRCSEQKRVRIPAMKVSEWGHLLRALEIERVCH"
     gene            complement(42363..42797)
                     /locus_tag="RH288_001531"
     CDS             complement(42363..42797)
                     /locus_tag="RH288_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="post-segregation killing protein PndC"
                     /protein_id="HDV4030601.1"
                     /translation="MTVSSTISVFCRDGVFRTVYCHLHGEPTWNGRILHTHYATGQQA
                     EALVEHGDIRCLGPRCDKPAGHTLQNPVDGVTAYYGRDSGFRMDSEAREYRSFREAIA
                     TESTEEVRFHYVFIDGYWKVMYRTPEGWKMKALALALRRCPK"
     gene            complement(43041..43385)
                     /locus_tag="RH288_001532"
     CDS             complement(43041..43385)
                     /locus_tag="RH288_001532"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030602.1"
                     /translation="MTLSPFLAVFYCAHFGSRLPGGIRSSGPTPTGSCWRTRQSPPNP
                     LARFRAAATVRCLKNQACSDRSGRAAPVAPETALPAHLTVCKATAPDGAVNPSAATPA
                     ACFPLWTFRGLE"
BASE COUNT        11436 a        11205 c        10617 g        10170 t
ORIGIN      
        1 gcacgcttgc agagaatgat tgttggcatt attttttgcc tcttttgagg ttagcatgcc
       61 gtctccacgc atccgtaaaa tgtccctgtc acgcgcactg gataagtacc tgaaaacagt
      121 ttctgttcac aagaaagggc atcaacagga gttttaccgg agcaatgtta tcaagcgata
      181 tcccattgcc cttcggaata tggacgaaat aacaaccgtt gatattgcta catacagaga
      241 cgttcgttta gcagaaatca acccccgaac gggtaaaccc attacaggta atactgtacg
      301 tcttgaactc gcccttctgt catctctgtt caatattgct cgtgttgaat ggggaacctg
      361 tcgtactaac ccggttgaac tggttcgcaa gccgaaagta tcctccggac gagatcgccg
      421 gctaacgtct tcagaagaac gtcgcctttc tcgctatttc cgcgaaaaaa atctgatgtt
      481 gtatgtcatt ttccatcttg cccttgagac agccatgcgg cagggcgaaa tactggcctt
      541 acgttgggag cacattgatt tgcgccacgg tgtggctcat ttacctgaaa ccaaaaacgg
      601 tcactcacgg gatgttcctc tgtccagacg tgcccgtaac tttcttcaga tgatgcccgt
      661 taatctccac ggcaatgttt ttgattacac cgcatccggc tttaaaaatg cctggagaat
      721 agccacacaa cgacttcgca tcgaggacct gcattttcac gatctacggc atgaagcaat
      781 aagccgcttc ttcgaactgg gtagcctgaa tgtaatggag attgctgcaa tatcaggaca
      841 tcgttccatg aatatgctga aacggtatac tcatcttcgt gcatggcaac tggtcagtaa
      901 acttgatgcc cgccggcggc agacacaaaa agtggcagca tggtttgtgc cgtatcctgc
      961 ccatatcacg accatcaatg aagaaaatgg gcagaaagcg catcgtattg agatcggtga
     1021 ttttgataac cttcacgtca ctgccacaac gaaagaggaa gcagttcacc gcgccagtga
     1081 ggttttgttg cgtacactgg ccattgcagc acagaaaggc gaacgtgtcc catctcccgg
     1141 agcgttacct gttaacgacc ctgactacat tatgatttgc cctctgaacc cgggcagcac
     1201 cccgctgtaa acatcattca aaacacatac agaaaggcga gttgcaacaa ctcgccaaac
     1261 acattcgatc tgcatgatcg aaattattcg tttcaccaga aaaaacaccg aagatacaat
     1321 aaccacatga gctgaaaaga ctttttcagt cggaggaaca atgagactga atacgaccgg
     1381 tattgcggcc cgaatgatgc tctcgctgga caaaaaagca atcggcgaaa aactcatcaa
     1441 cggtcgtcag ataaacccga cacctctgca ggtccgttac ccccaagggg taagagaagt
     1501 tctggggata atgagcgaac aattagccat atccaccgct gatttaaccc gaatcctgct
     1561 tgaggatgct cttcataata tgtttatgcc tgcggataac accgcaggga acataataag
     1621 cagaattgaa tacatcatgc tgtcgcatga tataaatgcg ccattactgg caacattgct
     1681 gtcgccatgg aatatccgct ccacggttat acaggacccg gccagacttg cagactatct
     1741 ttcagctgac gctctcgaac atcttgctga atgttttaat ctcaatccgg actggctgaa
     1801 tggccatgaa aactatccga tagcgttgtc cggtgaatgg ccagatactg ctgataattt
     1861 cagaatgctt attaatgata gcagcaacac tgaagttatt ttctggcata gtttcccctt
     1921 cgcaggaaac acgaaaagag aatattacgg ggtaatattg agacagaaaa aagaaataaa
     1981 tggttctgta atatatccgg cactatcatt atcaccaaca attctgaacg atgaaaaaag
     2041 aaaatggtta actgaatata caaccaggca gaatacaaca atgtctttgc gacgcgtcac
     2101 gttgagacct ggccttgccg ggaaccttat tacagggcaa atactacctg ttagcttatt
     2161 taatacgtct ttattaccct ggtaaatacc agatagtacc aaagtaaaaa attacggcac
     2221 atccgtgtca tagcgttgtt ttgtctaaat tctgataaac aggaaattaa atgatgaaga
     2281 aaaatcatat tacccgcacc atcattgcat ctgctgtatt attttccttt aacgctgcag
     2341 cagcgacgtc atattttgaa gcacgtaacg atgcaatggg gggcaccggg gtagcatctt
     2401 cccattatgg tgtggcacct ctggcaaacc cggctttact gacaaagcac aacagcaatg
     2461 atgatttcag ccttcttctg ccgtctgttg gggcacaagt tgctgatcct gatgatgtat
     2521 caaataaagc tgatgatgtt aaagatgact gggatttgtt tgatagtgct gttgataacc
     2581 agcatggcgt acaacaggca gcagcaaatc ttaaacatcg tctgcaggaa ttccgcaata
     2641 tcaatgcaga tgctcaggta ggtgtatcag ctgtagcagc catggcaaat gacactctgc
     2701 cgtttgccct tatggtcaag tcttacggaa ctgtcagcgt aaacggaaaa gtaaacgatg
     2761 cagacctgga ttatctggac aaagttgcca atggaacaat taccgacgtc gataagaatg
     2821 ccctgacctc acgcgcattc gggcgtgcag ctgtaattac tgacgtcgga atttcatttg
     2881 ccaaagaact ggaaacggcc ggacaaaaat ggtctcttgg cgtcacacca aaatatcagc
     2941 gtgtggacct gtttaactac aacgtaacgg ttcgtgatta cgacaaagac gattttgacg
     3001 gtgacaagta ccacaacacg aaaaacggat tcaacgccga tattggtgct tatacagacc
     3061 tgaatgacaa ctggactgtc ggtcttgttg cccagaacat cattccacgc agtattgata
     3121 ctaaagtcgt caatggcttt aaagaaacct tcaaagttcg tccacaggca accgccggtg
     3181 tatcctggca taatgacctg tttaccactg ctcttgacgt tgatctgact cctgccagtg
     3241 gcttcacttc tgacagcaaa cgtcagtttg caagtgttgg tgctgaattt aacgcatgga
     3301 aatgggcgca attgcgtgcc ggttatcgtc agaacatggc atcaaactcc ggaagcgcct
     3361 tcaccgctgg cgttggtatc tctccatttg acgtcgtaca tatcgatgtt tccggcctgg
     3421 taggaactga ccacgattac ggtgcaatgg cacaacttca gttcactttc tgattactgt
     3481 ccccgccccc ggcactaaac ccgggggtat ttttatattc agtttaaata acatgatgaa
     3541 accacgttct tcttattcaa aaacagcatt cattctttta ttttctgttt tcctggtagc
     3601 ggcagtgaca aaagcaaaaa gctcgcttcc cgatatcacc ctggaacagg caaaagaaat
     3661 taatgctgat aacaccgtta ttttcctttt ccgccatgga gaacattgcg accgttcaga
     3721 tatgccatgc tattcggata aaagcggaat cactattacc ggtacagaga aagcacagca
     3781 ggaaggtatt aagttcgcaa caatcttcag tgaatatgat atttactcca gcaatgcggt
     3841 aagaaccata caaactgcaa aattcttctc cggtaaagaa cccgtcgtta tggacagttt
     3901 atcagactgc aataatgatc tttataagac gcttgaatca atcgcaagag aatctcataa
     3961 aaggaacata gtaataatga cacataatca ttgtttatca tttctggcca gagataggct
     4021 cggcaagaaa ttcaaaccgg cgtaccttga tgccctgatc atgcattacg atggtacccg
     4081 gctcatactt gacggaaaat acaacaaaga ggcatagagg atatttgaat ttacataaat
     4141 tctgatatac tcagtaagat acaagagtgt acgggcacat gtgcctgtct gaattgcagg
     4201 ttatccggac gagggccggg aactgtttca gggacaagcg ccggtacgtt cgattcataa
     4261 atcgtcgagt catccatcat ggatcgattc ggcgcggagc gttaaagatt acgctcatat
     4321 tcgttttatg tctgacgaca catcaaccag ccagtatcag gaataatcac cttcagtaaa
     4381 ctatgaggct atttacctgg ccacactggc atttatttcc ggtaacgcaa gtatagccgg
     4441 aaacaaacat catcctgtct gtaccggagc accggtatat cccattctga tttaactgct
     4501 caggaattat tatgaaccgt attatacctg cggggtgtct tgccgccctt tttctggctg
     4561 gctgcaactc cccttctcag catactcctg ttccgcgtaa ctacggtgct gcctctgatg
     4621 tggcggttac ccggcacact cagtacacat tatgggacaa aggtgtgttt tccggccaac
     4681 ttccggtttc aacggggtct catcttctga cagctaacag cgatcgcctt tcctttgact
     4741 gggaaggtga tgcaattgaa ttactgaacg aactggccag agtcaggggg atgcagttta
     4801 actacaatgg tgtccgcctg ccgttaccag tcaaccttca cgtccgggat atgacgtttt
     4861 ccaatacgtt gagacttatt gaagcccaga cagcctggag agcaacaatc catcaatatc
     4921 cgggcttgtt acaggtcagc ttcatgcagc cggagaaccg gaaaaaatga aagcactcac
     4981 ctctctcatt ttgccagtaa tactgcttac tggttgttct tcttccccta ccatctcgcc
     5041 aggtggtgtc aatacgccac cacctgacat taatgcatgg cttaaaccac gaagtgaaaa
     5101 gccggatagt ctgtcagaaa cacgctggaa aatgctgacc gacgcaggta aaacgcttgg
     5161 atttcgtggt ggcaaggctc agcgttcatg ggagctgatt caggcactca acgcccggga
     5221 aagcacactt aatgccttat acgatttccg gccactgatt agcccggaag gctggctacc
     5281 accggttatt gatgaagcac aggacgtagc tcatatcacg ccagatcaaa tccggacctc
     5341 ttcccgggtc tggaccatca ttcgccctga acgctttgtc agcaatccac cgggctggcg
     5401 tgactggctt ctccgggggc tttcaacaac agccactccg ggtacagaag gcagcgtcgt
     5461 tccagaagac agcgtgcaac gaaaagtgtg ggaaaccgca ttacggcagg gatggcagga
     5521 aggaagacaa aacgccgacc tgacgcttga agccaaccag aaaaccctca cccgtgatta
     5581 ccggggcatg atgctgtact cacttctctg gcgtcagggc atgatcaccc gtccggatgt
     5641 ttctgatcaa atgcaaaccg ttacaggtga cgggaaaaaa ctggtcactg gagatcgtgt
     5701 tcgtcgcctt aaaaatcatg cggaattcaa tcttcagaaa tctcactggc gtccgcttat
     5761 aggcactgaa ggaggctccc gatgaatatt cctgatgagt ttggtctttt tccgtttcag
     5821 cgtttcacgg cagatgaact acggcatttc tttgtctggt gtgccgcaca taaagtcagt
     5881 gatgtggatc tgaccggcgg gtcacctgta tctgtcagtc gctttggccg acgggtgcgt
     5941 tgttccagtg caacgttacc aaccacactc atgtcctccc tgattgatga actgttcggt
     6001 cgggaagtca ttccccgcgt tctggcaggc aatccggttg acaggacgat acagattaac
     6061 ggggatgcat ccggtcgcta tggtcttaaa cgcggagaac gcatccggtt acgctctcac
     6121 ctcattcagg gcacatctgg tgcggaggag aaagcaatat caataaccat gcgtgtcatc
     6181 ccgacagaaa taccggacat cctctccatg aacattgaac cagacctgct tgaagcaatg
     6241 gtctgcaaaa gcggtctggg atttgtatgt ggtgaaaccg ggtcagggaa atcaacgctg
     6301 tgttcagcac tgtaccgtta cattatggac aatttccccg acgccaaaat cgtgacatat
     6361 gaagacccgg tggaatatat cctgggaaat gaaaacgatc tgctcccacc gcatcaggca
     6421 gaaatcgggc gtgatgtggt cagttttgct gccggactgc gttctgctgt acgacgtaat
     6481 cccgaaatta tcggtgttgg tgagatcagg gataacgaaa ccgccgacgc agcggtacag
     6541 gcaggcaaca ccgggcatta ctgcctgagc accatgcata cgaaatctcc tggtgaaacg
     6601 ctggcacgtc ttcttgggct gtttccccct gtcatcaggg attcgatggc ctgggctgtc
     6661 ctgtcactgt tgcagttcat tctggttcag gttctggtca gaacaaatga cggtggtcgt
     6721 aaagccgtcc gggaatatat cgtcattaac gatgagcttc gcgacaatct ttccggaatg
     6781 ccgcatgcag agtgggggca tcacattgat gccataatcc ggcaggagaa gcgccgtatc
     6841 cgggaccaga ttctggaaat gtatatccgg aatgaagttg accgaagaga agcgattctt
     6901 tttatcccgc caggggagtt acggtcatga aaagagaagg tttctggcga tatgcaacac
     6961 cgccagtcaa catccagggc gtacctctgc cgttcaccat gatttatctg tttatatgcc
     7021 cctttccctc caaaacaacc ttctggattt gcaccggcat cattttattt ttcgttattc
     7081 tcgaccgttc aggctggact gtcaggacga tctgtactcg cattttcagc attctgagag
     7141 gggccatcgc ctccggtcgt ccatggtggt atcgccacca tacggaatca ccacgagact
     7201 ggactggcct cgattaaatt ctggagtctt tatgtcaggt aaaaaaacta tcgttactct
     7261 gctccgggta tcgctactgg catgcccgtt actgttcacg acaccatcgt ttgcaatgat
     7321 cgacacgcca tccgtgaagg tcggcttttc tcctgaagga agcgcatccg ctctggtgct
     7381 tgacacaatc aacagtgcgg aaagctccat caggatgatg gcatattcct tcaccgaccc
     7441 ggatgtaatg catgcgctgg caaaagcgaa aaaacgcgga gtggacgtcc gtattgttgt
     7501 tgatgacaag gggaatacga accgggcaag tcaggaagcg atgaaatata tcaacctgct
     7561 ggacattcct ctccggactg tagatgcctt ccccatccat cacgacaaag tcatcattgt
     7621 tgacggaaac acggttgaaa ctggctccta taacttctct cgtgctgctg cacgcaagaa
     7681 ttcagagaat gtcgttgtgc tcaagaatat gccggatgta gccgcacaat atcttgaaca
     7741 ctggcaggat cgctggaata agggtacaga ctggagaccc tgacaaacat ttctcccccg
     7801 attttctatc cccccagcca cccccggctt ccggcggtgg tttttttccg tcttttttca
     7861 ggagaagcac tcatgccgtc tgtatcccgc taccgcacct ggcttgccgt gcctgcagat
     7921 gaaatagaag atctcaaaaa agcacatccc ccgatgaacg ggcacacgcc cgtcatctgg
     7981 gacaaggagc acaaactctg gttcgcccgc ccgggggcgg acctgtccag gctggaccgc
     8041 tggctgcccc ggccacagga cgtctccatg aacggcagtg atccggtcac cgagtttgcc
     8101 caggttctgg agaatgccgg actggttctg aaagaactgc cggtcatgga cgggaaaatc
     8161 caccgtgtcc cgaccgccga tgacaaaaaa ggacaaaaaa gtggcgcata tcgcggattc
     8221 ctggacggca gacctgccgg ctggtacagg gattatcgca gcgcggataa ttcgccgatc
     8281 acctggacct tctccggcgg agaacagaca gatccccgcg caagactcca cctgaaagcg
     8341 cattcaatgc aacgcaggga ggacgcggag cgggaactga aagcacagta caaccgacag
     8401 gccgcgtatg cccgccgcta tatcaacaaa tggccgcagg ccacagcaca tgaatacctg
     8461 acccggaaag gcattcaggc tgcaccgggg gtgcgggtaa acaacaaaaa tgaactggtt
     8521 attcccttca gtaaccgtaa cggcgcgata cgctcttacc agcgtattcc ggtcaccggg
     8581 gggaaagatg cccgcatcct gatagattcg gagaaaaccg gtaactggtt tgcgctgggc
     8641 acaccgcgca acggtcagcc ggtactgttt gccgagggct atgccactgc ggcctccctg
     8701 cacgaagcca cgggccttcc ggtactgatg acggtggatg gaggcaacat gattgccgtt
     8761 gccgaaaatg cccggcaaaa gtggacgcaa agccccttta tcttctgtgc cgacaacgat
     8821 catgcaatcc gggttaacaa aggtatcgtc agtgcaacaa aagccgcaga actgacagga
     8881 ggatcggtca tctttcctgc gttcaccgat gccgaaaaag cgcaggggct gaccgatttc
     8941 aatgacctgg acgcaagccg gggacgggcc gcttttcagc atgtcatcaa cgcccagtta
     9001 gaacacatcg gggtttccac ccccaacagt aacaccccgg aaatgcgcga ggcactggtg
     9061 ataggcaacc tcgtttttac accggtccac actgaggaaa aaaccatgac tccgacagaa
     9121 tatcctgaaa catcacccga tacagggcac agccatgacc agggaccttc tctgccgtcc
     9181 gccacgcagc aggaacaacc agctgcttcc agcagtaaca ttgctgatga aacacagtca
     9241 tttaccagtc acgccactga aaataacggc aaagatgagc ggcacgctga taacgttcag
     9301 gcgcaaacgg aaagctctgt agttcaggac tcccctgcag aatcaccggc gtccccggaa
     9361 agtacaacgg cgtctgcccc tgatgaaccc gctcatccgg cggaacctcc ggaaaaagtt
     9421 gtctcggtgg ccacagataa agactggcgt gaatttgaag ccgaactgtc acaaccggaa
     9481 aaaaacgagt cacaacagga atccggcact tcacctgaaa taccggcccc tgctgccacc
     9541 cccgcatccc ctgaagacag tccctcatct gaaaccatga atgaatcagc cgagccatca
     9601 ccttcccctg atgcagtcaa agaggaaatg accgtgatga cggagcctga tgacaaacaa
     9661 agcaccggaa tatccccgga tactccccgg gaagaggcgg tcaaccatgt aactgaagac
     9721 attccccttc agccagagcc gttccttcct gagtcagatg gccccgaaga atacgaaaac
     9781 tacagcgcat atcaggagct gatgaacaat gaaaatcctg agcatctgca ggaaaacagt
     9841 gatatgccgt cgcaaccgga cacaggccac gttcaggctg atgagtcaga acttcaggcc
     9901 acaacagata cagtagaacc ggctgtccgg gatgacccca ctccacagca acctgttcag
     9961 agcacatcat cttctgataa tacttcatcg tttctcgaca aagcgcgtgg cttttttacg
    10021 cgtaaaaaaa cggattcaca ggcgcatgag aacagtgatc ccaccccctc accggaaacc
    10081 acgacgacca caccggcacc tgacagtatt gtctacgccc cggaacgccc tgatgtaccg
    10141 atatcgctca atctggacga aatcattaaa tcgctggaag gtgaagaacg agcagacaga
    10201 accgtcctgt acaaactgga tggcaaacct gccttcattg accgggtaaa ccggctggaa
    10261 atggtcaacg gtgccagcaa tgacgatcgc agtgttctgg ctgcacttgc tgtggccact
    10321 gatttttatg gtggtgtcat tgagctgacg ggcagtgatg cctttaagca aaaagcgatg
    10381 cagttgatca tcgagcacaa catcaaagtg cgcatgaaat tcccggatca gcgagcggcg
    10441 ctcgaaaaat tacgcaagga aatggctgtc ggtaaggata ctgttgtcac ccataagcca
    10501 acaccggaac ttaaccggaa tacccctgaa caaccagcag tcccagaccc tgttaaggaa
    10561 aaagaagcca cacaatcccc ggcgtcccca gtagcccctg aagcatcaac cgtcagcacc
    10621 gtccctgcat catcaccggc tgaacctggc aaaacggcag atgcggcaca aggtgaagaa
    10681 ccaccaggaa aacttcgccc gggagagagc gtgactgccg tactgcacaa ttttggtcgt
    10741 gctgaatatg cacccggcaa aggagagagt ttctttgttg agcttaaaaa ccgcagtggc
    10801 agcaaactct actgggggga acaactggaa agtctggtca aaaaccacca gaaaggtgac
    10861 gtggtgacac tgacacttca gaaccgcgaa caattcatcc tcccgggaga gcaaaaagca
    10921 cgtttccgga ataagtggtc catggagtca gttaccaacg ggatctcggt atcacatgat
    10981 aatccggata aaggtcagcg tattcaggcg attccggtcg aaacctttat gaaagtggct
    11041 gcgcaaatca gccaggggtg gcccgaagag atgaaagcgt tacgtatgcc agaaaacgtc
    11101 ggctcacatc tgtttatcgg tgaagaccga catccggtct ccgcgccaca gaacgcaaat
    11161 caggtaacag aaataaccag cgcagcccct gacaagctga cacctgttct gggatcagtg
    11221 gataaggata cgcgtgaact caacctgcta cttgtccaga gtgccgatga acatctgcag
    11281 ggtgtggtcc ggctgaacgg cacattgtat ccggcactgg ccaccccatc agccgacaac
    11341 agtcagctgg ttatcaatgc gctgaccgac aaaggtttac gctttgcagg ttatggtgaa
    11401 gcggtaaacc acgatgctga cagcacgaat cgccctgcac cggagcttat gcagtttcat
    11461 ctgaaaaccc gggaagaacc gctttttgct gctgtctaca cgccggaaaa acaacctgat
    11521 gcgttgtacc ggaacctggg cttcgagcag tcatggcagc agtggtccaa cagccaaaag
    11581 ccggaggaca ggcaggaaaa aactctgcat caggatctct cccacagccc cggccgatga
    11641 gccggtaagg aagccatatg aacatgcata agtctctggt tgccgtgctc ggccttatcc
    11701 tgatttcatc cacggcaagt gctgcaacct gtcgtgcggg tagcgcggca caggccggta
    11761 gtaatacagg atatgagcga gcacgtgcag ctgcggatgc atggtcacaa cgtgaaaacg
    11821 atgtttcctc atccctgcag tcctgtctgt cacgaatcaa aaaaatcagc ataaacctcc
    11881 cccagttccc cagccttgac gacattctgt cgcagctgga aaaccaggtc tgcgacgcgg
    11941 tcgtggacaa ggtgaatgaa aagctgccgg ggaatattga tccctggaag gactacaacc
    12001 tatgaccgaa aataccgagc catcctcgcc atcacatccg gcacctgacc cggaaatact
    12061 gaagagcaca atcagggcta tgaagcagtc agaacagcgg gcaaataatg tccctgcgct
    12121 gataaaagcg cttttatgta cgggcacatg tcttcttatc agtattactg gtaacgccat
    12181 tcagtactgg cactcaacga atgtggagcg cgaatatttc gctacagaca atggtcgtct
    12241 ggtcaggctg gcaccaacaa gtcagccagc atggagtcag aatgatgcaa tggcctttgg
    12301 cagccaggca ctggcgaccg cattcaacct ggattttgtg cactatcgtt cacagatctc
    12361 ctccctgtct ccgcgttttt ctgacgaagg ttttgtcgga tatgtgaatg cattacaggc
    12421 atctaacatt ctggagacga tcaagaaaga gaagatgaat ctgaccgcca cgacaggtgc
    12481 tggcgttctg gtacgacagg gacaaatgtc cgacggcgta tggttctgga cattccagta
    12541 tcctgtccgt atgcgtctgg tcggccagac aaccagcaag ccagaacagt cttttgtttt
    12601 cgaaatcacc atccagcgtg ttgaccccag actgaaacca tccggtatgg aaatccggca
    12661 gatgatctcc cgtaacgccg gaccgaactc ctgagataag taatatgcaa tcacgttatt
    12721 tactgagcac actgctcctg gtgtgcagcg ccgccacgtc tgcagataac gcaggatggc
    12781 agaacgcacg cacaccacaa acgacaaatt ctgccagcga tcacgttcag aacgcctccc
    12841 aaaacaccgg aggtgttccg gcaacactgg taaaaggtga gctgcctgcc cccgggcagg
    12901 ccagcccgct ggtacaggat gcggcaaggc ttgattctga gctctccgcc gatgagattc
    12961 gctcactacg cagtctcatg gcggataacg agcgggccat caatgcgccc atcaccagtg
    13021 ttgtaccccg tatcagctct ctgacagtta atctgtcccc cggtgccagc cttcctcttg
    13081 ttcgcacagc catgaacaac ctgagcgtgg tgacatttac cgatatcaac ggttcaccat
    13141 ggccacaatc cgatcctcct tataacgcgg caccaaaact ctttgatgtg cagtacaacg
    13201 agaacatggt gacaatcaca ccattgcggc catgggcatc cggaaatatt tctgtctacc
    13261 tgaaaggtct gtcggtaccg gtcatcctga acgtaaccag tggcgaaaca gatacgccgt
    13321 catccagtca ggaaatggac agtcgtctgg atctgcgaat accacggcag ggaccaacca
    13381 gcccggttgt ctccatcccg acggataaga tcgccctgca tgatgcaaca ttacaggcat
    13441 ttctggatgg tattcctccc cgggaccctt cagttaagag gctgaaattc acaggtaatg
    13501 tcccggatac aacgatctgg caacacggcg atgaccttct ggttcgttcc cgggcgatgt
    13561 tgcgcgatga atttgaacag accttgtcct ctgccgacgg aactcatctc tggaaacttc
    13621 ccgtcacccc actactgact ttctctgtga atggccagtc cattcacgtg acaccagaac
    13681 tggagtaatc atgagtgctg aacaggatgc cggtaaatcc ggaaagaaac tggctgccct
    13741 gcttggactg ggcagcatca tcttatttgg cggcggctat atcgcgtttt ccaaactatc
    13801 agggagtaac agcgatatgc agtcagccgt gaacattaac agtgcagcaa gcggcggaac
    13861 gcgcagcgtt accgaaacgc ctcactatcg tgaactgtta agagcggata atgaacgagg
    13921 ggccgcagct gcagcccgca ataatcagac gttcattgcc agtcttccac aggggcttga
    13981 tattccggac actcaggaaa agcaacaaca gcctgcagca aaaccggaaa actatgctca
    14041 tcgccaggct tccggcacac cacaggagga tcgagcagcc agtgaaaaac gtatggagcg
    14101 gctgcaaaag ctgattgtaa gaataaaaga tcagcatcct gccggtagta caccaaccat
    14161 agcaacgact atgtggaata aatctccggc agaaacaaca gggcagaatg gtacgcagca
    14221 attcgcatta aagaatgcca gcctgtccac gcctgtagca gaaaaaggga tacaactgat
    14281 acctgccctg acccgtatac cggcatatat tgatactgca gtggattctg ataacccgtc
    14341 atccaaggtt atcgcaacca ttcccgctgg cccctgggca ggggcaacgc tgttcagtcc
    14401 gggagtcaaa ctggtgggta acggcgtgga gatccatttc gaccggatga gctggaacgg
    14461 catggacctt aaggtcaatg catatgctca acgggaagac aacctgatgt catccgtggc
    14521 cagcaatgtg aatacacgct ggtttaaaca tatcattctg ccgtcagtgt taggaggtgt
    14581 gggcagtatt ggcacacttt ataaagatgc caacacgcag gttattcagg gtaactatgg
    14641 cacggttacc ggacgcgtgg gaatgcccag tggtgaagct gttgcgggcg ttattgccgg
    14701 tggtatggcg gaaagaggaa gtcagatatt aacccgccag gcagaaagtg agccctataa
    14761 acaggtagaa gtgtatcagc atgaagtcgt atcaattctg tttgttgacc cggtaatgac
    14821 aaacgacgcc aggtcatctt ccctttccag tggcatttcc ccttcagtta atcgtacatc
    14881 acaggcggaa caacgctcgc aggcacgaat gcagacagcc atggagcaaa gaaaagctgt
    14941 gatgcaacgt cggtatgatg aacaaccgga gacaccataa tgaaacctga aacagaaata
    15001 gatgaaaccg gcagcttcgg tgaacccgaa gagaaacccg cccccttctg gaaacgttcc
    15061 gtctggggga tatctgtagc aacatggggg ctatgtgcag tcgtgttgct cgcagccata
    15121 tggtatctgt tcctgagagc gccatcggaa acaggcatgc ctccgtttaa tgatgcggat
    15181 gctggcgtac agacctggca aaccacacaa gaatcatcac cttccgttca gtccactgag
    15241 actatgactg tccggacagg agaagatatg agccagcttg cccgggatgt aaaaacagag
    15301 ctggataacc gcgatgaaaa aattcaggca acactgaata tgcttcacga cagcattaac
    15361 aagctgggcg aagctataaa aaaggatgaa gaatacgcac aggaaacacg ccgtcagctg
    15421 gatgatatcc ggagccgcct gaacggaata atgacacaga aaagcgtcac tgaatcctct
    15481 tccacaccgc atccagcaaa gaaaaaaacg tcgtctgtac ttaacggaat gaaaatcatg
    15541 tcgatggaaa ctggtatggc ctggattcgc tggcagggta gtacctgggc tgtcagagaa
    15601 ggtcagacgc tgggcaatgt ggtgatccag cggattgatc cgactacccg gaccatcatc
    15661 accagtgcag ggacgttacg ctgatgaaca tggatgccct gaccgccatt gagaactttg
    15721 ccagcagtat tttcagtgcc ggaatggatt tcctgtttac ctggggagaa ttcatcgggg
    15781 tgatcagcat gattaccctg tttgcccgcg cccgttcagc cggtccggta aaaatgtctc
    15841 ccggaaaatt tattgcgggg atgttaacca gctgcatgct cgtatcactc ccagcaatga
    15901 ttaacgccgg aggcgtacaa atgggattca gggctgactc atttggcccg attgcatatg
    15961 tacaacctca gacgtttggc gctgctgctg gcgcagcaaa tgcagttctg tcgctggcca
    16021 agctggccgg tgttggattt gtaatgaacg ggatatccat ctggcgcaag gccggactcg
    16081 atggacatac cgcactgagt gccagtgaat ccgtcagtaa gggaaacgtc aaatttattg
    16141 ccggcgtcct gctggtcttt atcgatcgtg tcctcaatgc cctgctggca agcattggaa
    16201 tcgtcttctg atttttttca ccttcatata aaccactgat atatccattt aaggagaaac
    16261 tatgtcacgt attcgtgtcg tagcggcccg tctgtacgcc gcatttatcc acgcacaact
    16321 gtttgtaatg tcatgccgga gcaaactgac taagttcctg ctgctcattc ccatgatgtt
    16381 gctgcccaaa gccgttcttg ccgatggaga tcttgccgat atggttcgca atgtcgaaca
    16441 aggtgccaaa acagcacagt catcatcact gactattgcg cagttcatcg gcgtaattct
    16501 gtttctcggg ggcctgattg gcctgaaaaa agttgggaaa caagggggga tgggactggc
    16561 tagttgcatt gtatctatcg tcattggggc ggtacttgtc gccggacctg aaatgatgag
    16621 tcgcagccag aaacagttgg ggatttcctc aatttccatt ggctaatctt gtccagggca
    16681 ctggcattta tccggtgccc ttcctgttcg gcaatacaag gaggcacata tgtctgcctg
    16741 gagcccggag cacataacgt tacgacgaac agaaaacggc aatgtgattg cccacgacag
    16801 tcgggacgat caggaattca tttttgcaga atgctgttcc gatgaaatcg caaacatcat
    16861 tctggaagcc gtgaaacgtt acaccagtac ggagcctgct catgcaacac agcattaaag
    16921 acttgtggtt gtatcccttt ccagaaattg atgtggttca tacacaggag ccactgttac
    16981 cggaaccgga attaacaacg cccggtcgat gtatctgctg ccggcaaaac gtcaggcacc
    17041 gtttcagact ggatgactca tggccactca gacagcttac cgacacaatc agtgacacac
    17101 gagttcgtct taataaagcc acagaacatc tggataagtt aaaaaagcgt ggtgaaccag
    17161 tcgcaaccgg cgaaaaggaa aagtacaaca cggcagtaaa agccgctgaa cgggcgcttg
    17221 agcaggcccg tctgtctgcc agacgtcttt cactccgcca tgtacagaaa gctgaaatca
    17281 ccagtacaga gtcgttgtca gagaaagagc aggaactgtt tcatgaagac ggcccgcctt
    17341 acagcttatg tgctttctgc cacgcctggc attcactgaa tggttatgcc gcagcacagg
    17401 gcgttatggt gtggctaccc gaccttcatc catccacggt cgtggccctt aaccgtcgtt
    17461 cattacagga agttttcagt aatgataagt tccgggtccg gcggggacgg gaagcgctct
    17521 ctgcactgat gcaaaacaga ctggcggttg aggataaatt ccgcagtttc cgcccggccg
    17581 atttcgctga cgtttttcgt cgctatccac cttctggtcg ttcgcccctg cgtgaaaaaa
    17641 tgaacgggat tgccctgatt ctgacaccag attcattcat caaaaaagaa tacgttgatt
    17701 gatttttctt catgccactc cagcgcgggg tggcattaaa aaaatcaaac tgcacaaacc
    17761 tccctcctgt aagtccggag ttccctcacc tatgaacata aaccgtttca tcttcactat
    17821 cgaagactgt ctgaacacgc tatcccgttt ctctgtcgca agcagttttg ttgagtattg
    17881 cgatttacgt actgtaattg gtctggacag acaggatcgt gaacgtcgcc catggcttaa
    17941 ttcgccctat attgcagcca caaagcgtgg agaatatctc tctgtctttg aagtcagcgg
    18001 tgctttcaag gaaatggatg aagcatccga ccagactggc ccaggttcac tggaatcgct
    18061 gatcaccagc atgagtgaca gcctgaatac ggcatataaa aacagcggtc ataaaatcag
    18121 ctgcgttttc gagcgtgacc ctgaaatggg gaaagaagaa atcgaagaca tggtcgcccc
    18181 acaaaaacgc tcactggcta atacaggtat ccagttacag gatgtggtcg atgagaaagt
    18241 cacaacactg tccccatggc tggtccggga gcgctgctgg ctggcgatct ggagtggacc
    18301 cgaccttatc agcaacagcg atcgcaccgc ccatgatgag cttgtcagaa gactggctga
    18361 acgggtaccg aaagcacgct ttgcccagtc cccctggcag tggaccttat ctgcactgaa
    18421 aatccgccac gaagcttttc ttgataatgt ggaacaggca ctgagacatt catctgatgg
    18481 cctgattctc cggctactgg atatacacga ggtcgggcgt gaaatacgtc gtcagacaga
    18541 acggtacagc acaccgcgta actggcaacc ccacctgcct gaagatgccc agccagcggg
    18601 atatcgctgg actgacgatg aatccgtact acatgctcct tcattgcatt tgcagttatt
    18661 caacacgcag gtgaccacac agggcaacct ggttcaggcg ggcggactct ggcacggaat
    18721 ggtatcgatt actttacctc cgcaaaatct gcagacgttt aacgaactgg tccgtgccgt
    18781 cccccgcgca gtcccctggc gcatcagaat ggatctgatg cccggcggga tgaaggctct
    18841 taatctgaag aaaacgcttc tgacttacag cagcttcatt tctgccgttc gtccaatgta
    18901 tgaatccgtt atgactctgg cggcaacgga tgaaaaagaa cctgtctgca taatgaccat
    18961 catggcctcc acgtggggaa aaacacgtga aatatgcgca cgaaaccagg ccattctgaa
    19021 atcggccatt gaaggctggg gcgtatgtgg caccacgaca acatttggcg atccccgacg
    19081 cgcctgggtg aataccattc tcgcggcgtc cggaggctcc ggcccggttc ccctgtatcc
    19141 cccgttgtca catgccatct cgcttttccc gcttaacagg gcaggctctg tctggcgagg
    19201 caaagggaat ctgatgttac atacagaaga cggttccgca tttgaggttg gtctggcgtc
    19261 atcccaacaa aataaacata cagaactggc accaggcgat ccgggactgg gtaaatcagt
    19321 tctgattaat acgttgtcgg aaatacagat atcatctgct cagaaaaacc tgcccttcat
    19381 tgcctatatc gataagggat acagtgctca gggactggtt cagcttattc gcgacagtct
    19441 tcctccggaa agaaaagacg aagctgtcgg tattattctg agcaatgatc cggaatacac
    19501 ccgtaacctt tttgacgtga tgtacggcgc taaaaagcct attacgccgg aaaagaattt
    19561 catgtcatcg gtgctgtgtg ctctctgtgt cgataccggt accggtcaac cctgtaaccc
    19621 cggagacacc cgacaaatta tcaaccagct tatcgagctg gcttttaaag agtacggtga
    19681 aaataatccg cgactttatc gcgcttcaac ggaagaactg gtggattcag cactgcagga
    19741 ctcgggactg tatgaaaaac atgatgcagc ctggtgggcc agatcaacct ggttcgaagt
    19801 ccgggatatg ctccacaatg ccgggtatat catggcggct cagcgggctc attatcaggc
    19861 aatgccccag cttcccgaag tgtcctcgat gctgggccat accagtctca gggatgtttt
    19921 cggtactgtt cagcgtgatg gttcaaacga gcttctgctg gactacatcc gccgcgccct
    19981 ggagcaggga cataacgact accccatgat atccgggtat acccggttta tgatcaaccc
    20041 ggaaacccgg gtcatcgctg tcgatctgaa taatgttgcc ggtgacaaaa cgcctgcagg
    20101 caggcttaaa accggcatca tgtacctgct tgcaggtcag atcgccggtg gtgacttcac
    20161 cctgccacaa tacagggatg aagtgttaaa gcagcttcca cgggaatacc atgaaatcgc
    20221 tcttaaacgt attaaccaac ttgatcagga ggttaagaca aaagtttatg atgaactgca
    20281 taacgcccgg ggaattgact tcatctggga aaatctggat acccaggagc gcgaacaacg
    20341 caagtttgct atccgcacgg ttctgagtac gcagtatctg agggactacc cggaaagcgt
    20401 tcttaagtca gcaaatactc tctggttaat acgctacaaa cccgaagata tccccgtact
    20461 gagggataac ttcaacgtgc ctgaatttat gctgaaacgc ttcctgaaaa tgccggaagg
    20521 cccggcacca gatggtagtg gtgttcctgt tctgggagta ttcagggtaa aaagtggcac
    20581 gcttgcgaga atactcaaat ttaccgtcgg tccactggag ctatgggcgc tgaactcatc
    20641 gccaaaagac agtgccctgc gtaaaacgct gacaaataag ttaggttcag ttcgggcacg
    20701 taagattctg gccgaaaact tccccagagg ttctgcaacg tcattaattg agcaccgggc
    20761 gggccaacat aacagtgaca atgttattga agatctggcc tcggagctca tccgaaaaca
    20821 gggatacaat ctctgatgtg tacaattcat atcaccccac gctgccggag acctgccaga
    20881 gggcaggtat ttcttaaaaa acttgaggta aaaggtgaca gtttctcatt cactctgccg
    20941 tcacgtctct tcaggttaca tccggccccc aatcccagag tgatatacgc ctcggatgcc
    21001 agaacacagg gaaaggttac aggcatgcgg ctgttgttgc cgtccagcac agatgagctg
    21061 ataacaacgg caatatggca ggtttctgtc ccggatgaag caccattcga cgttcagcat
    21121 gtcatccagt ggatactccc ttcaccgctg gcttcgctga tgtccgatga tacctggtta
    21181 tggccatccg ttcccggaac gccggcactg agtgccggtg actggcctgt catggatact
    21241 gacccgtcca ccttacggcg cgtcagacgt cgttctttca gcatcatcga taaccggaac
    21301 aggaaaggtt atatcaccag gcgatatcag tgttttccac tggccccact acctgaagac
    21361 agaaaatacg acagccttcc tgaccttgtg ctccaccccg agcaggagac aataaaatgc
    21421 aaagaaaaac attactcgca gcccttatag ccatcctgag tggaacggca tgccaggctc
    21481 atgcgtattc agtcaccgtc gtcgccagcc gccccgttga acagcaggtc gtccccagaa
    21541 tggaggccat caaaggtgtg ctgagtgaca tactgagtac ccagacagcc acgggtaccg
    21601 ctatcaatca gaactctgaa aagctggcaa gtgtcattgc ccagaacgga caggcgacac
    21661 gtcagcagat gattttcagt aatgaaactc agcgcctcga ggaggcacgg aaaagcttca
    21721 ccgtgccaga ctccatctgc agtgaatccg catcagggat tgcaacagaa agcaaaagtg
    21781 cctcagcatc cgcagcctca aaactcagta aaggtggcgg tgtgagcaac cgtaacatcc
    21841 gcgaccgtct ggccagcgca gcaaactctc ccgtgcggga agcttatgat ggcgcggcca
    21901 tacacgccag ttactgtaca gaagcagaat atgcacgttt tggaggaacc gccgtttgtc
    21961 cttctgtggg cgaaatacca ggtggagaca gtcaggtacg ctcgatttat cacggcgcag
    22021 gtacagcgga cacacctgcg gcactgacat gggatcagaa gcaaatagat gcagcgacgg
    22081 cttacatgaa aaacacttcc cgcccctctg ccggtcgtgc tctgggtaaa ggagaagtga
    22141 atacccagag tgggcgaacc tacgtcggac tccagaacga atacaacggc atcattgatt
    22201 ctgcgtcgaa tccccaactg acgttgattg ctgacagcac gcctaatgaa agcacacgta
    22261 aagcactggc tgaaacactg cagtcagact cagcggccgc ttacttcgac caggtggctt
    22321 caccagaagc aaaagcacgg ggatatatga gtacccgtga gtttgaagct tttgaggctg
    22381 gccggcgcta cgccaacaca gcatacctgg tggatttaca ggaaatgcag ggggataacc
    22441 tgctccgtga actggtaaga atcactgcgc aaatgaactg gcagctgaac gatctgaaag
    22501 aacagatccg ccagggtaat gttatctctg gccagcaact ggctctgact gcccgccagt
    22561 attatgaaaa acaactcggt agccttgaga aaacaatcaa tcaggcaaac gcacgttgaa
    22621 agctgacgtc agaacaggac tgaaaaaatg aataagttac cggaaaattc agaccagacg
    22681 aaaaacgtca aaaaatcacc atccataacc cgcatagcca cccggaggat tattaacatt
    22741 tttgttccgc tgatggagac tcgcctgata acgaattctg tacagcatat gctaaagcaa
    22801 caaaaaagca ggctggaaaa attccgtcag gtaaataata aaaaggcgca actctgcctc
    22861 tcgtgggaag aagctctgct ggccagccat atgtcagtag acgatctgga tcgccgtttc
    22921 cgtcggcgca gaacagcatg gcggttatgc tgctggagtc tgctggccat cgctttattc
    22981 ctcagcggta tgctctttgc cgcctcctca ttacctttga tgacactggt acgcgccatc
    23041 agcactctta tgttgatact gtcaggcgtc gctctttgtg cttccagagc tctgatagtt
    23101 acataccgcc tctggcagtt gcatgaacga aaagtcagcg aacccgagca ggggactttc
    23161 cgtgattttc tgaacgaccg caatggctgg cgcaatgcca cattaattgc cgtaaccagt
    23221 aaacaatact gatcacgtcc agatgccagt accactggca tgtcgccatc ccccttaatt
    23281 aaatcctgtg tggcctttgc ccatacgcaa ttctattccg gagttactgt gaaaatttta
    23341 cttcgcgcac tctgtgcagg ccttgctata tcctcactgc cggcaatggc ttcagtgacc
    23401 tatcaggata ttgtgtctgc cgccaccaat cctgacgatc tgtcccgcca ggcgctggtc
    23461 acgatattcg gtgatgtggt caccaatcca ctgtcaacca gcgaccccac cctgatcgga
    23521 agcatgttct gggtgttcaa caatatcatt gccgtacttg ctatcgtctg gtgtatcttc
    23581 attagtatcc gccatgttgt gcgttcgggg catcagggac aggtattcag cgtcgggcgc
    23641 gatattgtcg gcatactgag tttcgtcgca ggttttctga tgatcgttcc taccggaaat
    23701 ggctggagtc tcgctcagct cattatgtta tggggcgcat cgataatggg ggttgggtcc
    23761 gccaatgtga tggtgcaagt tgccgctgat aatatcgcaa atggttattc aatgactgta
    23821 cagccagttc aggcatccac acgaacagct gcgcgtggca tttttgaaat ggaattatgt
    23881 aagtatgcgg ttaacgcagg actaaatgat tttaatcaga ccgccaaatc ctcgacttca
    23941 ctgatgacag aatcagctaa aaccgccagt ggtaattaca ctgtcacggt atccaatggc
    24001 agcggtatct gtggtacagc cagcctgtca gtagaaggaa acggaacaac agatcagtcg
    24061 acgattggaa aattctttaa tcccttcagt aaaaacgagt acagcggtgt tatctcagca
    24121 caacgtgcag ccatggataa tatgattagc gacatggaca acgctgccag tgagtttgtg
    24181 acaacatttc tggaaaaaag aaattctggc aacggaacac tgccggatat cgagacacga
    24241 attcagaaag cagccgacga atacgaacgt gctgtgcaaa aatcgctacc cactgataac
    24301 ggagagcaat ccagaaaaga ggctcttaaa tcttatctca caacctacgg gtgggtaacg
    24361 cttggcgcat ggtatcagac ctttgccact gctaaccagc gtctggcaga gctggctgac
    24421 agagctccag ctgtaacttc aatgtcatca ctgggagaag ttggtgatac tgacttattc
    24481 agtgcggtca tgagtgccta taggacgcaa ctgcagaatt cctcctatac gccaccgctg
    24541 ggcacagtag tatcatccag tgaacaacgc atggcaaatg cacaagatcc gaaatctgcc
    24601 ttgtctgaaa ttatgggccc ccttgttagt ctcactaaca ggattgcaac ggaaacaagt
    24661 ggcacaggca caaccagtgc tcaaattaat cctctgataa aaatgaaaaa tatcggagat
    24721 ataacaatgg taagtgcaga aggaatctgg actatatata caacggccag agttgtcgtt
    24781 gccggtggca aagattcaat tcttgtaaaa ttcttcaact cactaacagg tgccgcttcg
    24841 atgcttaccg cgctgtttga agcacttgca ccacctgttt attttctttt gttcctgatg
    24901 ttctgtgctg gattttcctt atcaatttac ctgccattca ttccgtttat tttctggatg
    24961 acaggcatcg ggaactggat agtcagcgta ttaataggat gtaccgccgg gccgctgtgg
    25021 gctgcaacac atctcgggac atcagaagac agaggaagtc gggcagccta cggttatata
    25081 tacttaattg atagtatgat aaggccgccc atcatggtct ttggtttttt ctttgcttct
    25141 gtagccatca tcgccgtagg cacaatactg aatgcattat ttggcgctgc cctggttaac
    25201 gtacagttca attcgctgac cggtattttc agtcttgctg gtttcttgct gatatacgcc
    25261 agaatttgta caaccactgt agctgccata tttgcccttc aggcctacct acctgatcat
    25321 gttattaact tcctaggggg acgtgatgga gccaacacgc ttggcagcat ggcaaattct
    25381 gttaaagaaa tatttattgg aggaagtcgc aatatccgac atactcctgg aatgaaaaca
    25441 gatcgtctta aagataatac aaaaggaagt gacgacaagg acggaataaa aggataatat
    25501 caatataaat attgcacaac ctccccatcg gcattaaaat aatagatagt acgaggggag
    25561 gcattatatg aaagctaaaa aagaaacaac agacagattt ccaacctggt ggctatttta
    25621 ttatgtatta agaaaagctt atttctttct tggaatacct ttttttctgt tctgcgcatt
    25681 aggctttacc gaaatgctat gttctgatcg ttatttcgga aataaggtcg aagattatgt
    25741 tgtcactttc ggtagttggt tcttattact tgcgccaggc atatggatgt actcacgtgc
    25801 aaaaacaagg agagaaaaaa taagaaaagt tgtacaaaca ataaaagagt caggcttcta
    25861 ctctccagag aaggggtatg agggattatc tttaacccag ggagcttatt tcggcattga
    25921 ccttaaaaat ggcacaatgt tgtatgtccg tatctatcca ggcaacatta tggatgttat
    25981 cggttttgac attcataatt tcactcgtac tgtaacagac gacaaaaaac tggaaattca
    26041 tacgaaatac atcaatctgc caatggttcc tgttccatca tggtgtgctc atccagaaac
    26101 agcatcaaac accatgcacg caatggcaag tcgaggatat gattaccctg tcgactttcc
    26161 tcgcctgatt caggaaaagc gtaaggagtg ggagcagatt gcaggcatgc ctgtagccga
    26221 agtattttaa gataagctcc ctccataaca gccggttcaa atgagccggc ttttgttcat
    26281 tacaacagat aacttatgcc gttaccgata aattcgacca agtgctttaa tcgcagcaat
    26341 ttttatttcc atatcatcac tttgactcaa tctatgtaat tcacgagtaa tgttctccgc
    26401 ctgacaccgg ccttcaccta atgcatagat cgcagcaagt gtaacgtctt ttgatttact
    26461 cttcatcatt tcaaacaaga aagtattagc tatcgcagga ggcatgctca taatcaatcc
    26521 tcttcatgaa ataaacaatg gcactcactt acaaacagga gtccactatc gcaagcgact
    26581 caacttagca atatctctca atttgaatga aaaaaccaga tggcatgtga cagggaaccg
    26641 tccgcatgat gtccgtgacc atttaacccc ataagctaac cttgtcacaa acgggcgcag
    26701 aacagcctgc cagacagaca acaaaacaaa agtccaagat aaaacatgaa taccggtatc
    26761 tcaatgcgaa gaaataatct ccgtagaacc ccccatgaga aaaatatcat atgggagaaa
    26821 atcgcaatta tcacagccag cgcattcatt attttcgctg tgctctggca ttaattattt
    26881 tcaacacaaa aaggaaaaaa caatgaatct ggtagacgcc tttgtcaaaa aagtaatatc
    26941 cgggccatat gaagaatatg gaaaatggtg gatagatgtt gaatacattt catggggtgt
    27001 tcccgggaaa acaagactga tgtttgagtc aaaggagcag gcactggaag ttaaagaagg
    27061 gtacaaattt ttaacgtgag atctcttttt tgattagcag gatttttgac atagtgtggg
    27121 acaaagcata gaattgatta tgttagatac agactgtctt ttcccgccca gagcaaccaa
    27181 ctctgtagcg gaacagtaaa aaagccgacc tcaccagtcg gtttttttac atctgttgtt
    27241 tctgcaaatc cgccccacca tgcctgttat accgggaaga ctcatgttct ggttaccgtc
    27301 atcacgacag aagtgtcgcc agacagtgct aacctgcgga ttacaagggt ggttgttatc
    27361 aaatgaacag aacactatta taagaacgtt agctgaaaag agatttcctc cagtcagggc
    27421 caccaactct gtaacggaac agtaagaaaa ccgacctcat cagtcggttt ttttacattt
    27481 attacttctg agtaacgaca agctgtacgt agcaagctcc ctctggcgtg gaggacgtca
    27541 gcgggctact ataatgttgt ctaggcatta cagtagagcc cttggttgat tgatagaaca
    27601 atctcccggg gctttcacaa acgctttcag cttacagcct caagctcccc accgcgattt
    27661 tgacgacttt cgtattttgc aacaatatca ggtggtcagc ctttcccgta aactgtcacg
    27721 aacggtgcaa tagtgatcca cacccaacgc ctgaaatcag atccaggggg taatctgctc
    27781 tcctgattca ggagagctta tggtcacttt tgagacagtt atggaaatta aaatcctgca
    27841 caagcaggga atgagtagcc gggcgattgc cagagaactg gggatctccc gcaataccgt
    27901 taaacgttat ttgcaggcaa aatctgagcc gccaaaatat acgccgcgac ctgctgttgc
    27961 ttcactcctg gatgaatacc gggattatat tcgtcaacgc atcgccgatg ctcatcctta
    28021 caaaatcccg gcaacggtaa tcgctcgcga gatcagagac ctgggatatc gtggcggaat
    28081 gaccattctc agggcattca ttcgttctct ctcggttcct caggagcagg agcctgccgt
    28141 tcggttcgaa actgaacccg gacgacagat gcaggttgac tggggcacta tgcgtaatgg
    28201 tcgctcaccg cttcacgtgt tcgttgctgt tctcggatac agccgaatgc tgtacatcga
    28261 attcactgac aatatgcgtt atgacacgct ggagacctgc catcgtaatg cgttccgctt
    28321 ctttggtggt gtgccgcgcg aagtgttgta tgacaatatg aaaactgtgg ttctgcaacg
    28381 tgacgcatat cagaccggtc agcaccggtt ccatccttcg ctgtggcagt tcggcaagga
    28441 gatgggcttc tctccccgac tgtgtcgccc cttcagggca cagactaaag gtaaggtgga
    28501 acggatggtg cagtacaccc gtaacagttt ttacatccca ctaatgactc gcctgcgccc
    28561 gatggggatc actgtcgatg ttgaaacagc caaccgccac ggtctgcgct ggctgcacga
    28621 tgtcgctaac caacgaaagc atgaaacaat ccaggcacgt ccctgcgatc gctggctcga
    28681 agagcagcag tccatgctgg cactgcctcc ggagaaaaaa gagtatgacg tgcatcttga
    28741 tgaaaatctg gtgaacttcg acaaacaccc cctgcatcat ccactctcca tctacgactc
    28801 attctgcaga ggagtggcgt gatgatggaa ctgcaacatc aacgactgat ggtgctcgcc
    28861 gggcagttgc aactggaaag ccttataagc gcagcgcctg cgctgtcaca acaggcagta
    28921 gaccaggaat ggagttatat ggacttcctg gagcatctgc ttcatgaaga aaaactggca
    28981 cgtcatcaac gtaaacaggc gatgtatacc cgaatggcag ccttcccggc ggtgaaaacg
    29041 ttcgaagagt atgacttcac attcgccacc ggagcaccgc agaagcaact ccagtcgtta
    29101 cgctcactca gcttcataga acgtaatgaa aatatcgtat tactggggcc atcaggtgtg
    29161 gggaaaaccc atctggcaat agcgatgggc tatgaagcag tccgtgcagg tatcaaagtt
    29221 cgcttcacaa cagcagcaga tctgttactt cagttatcta cggcacaacg tcagggccgt
    29281 tataaaacga cgcttcagcg tggagtaatg gccccccgcc tgctcatcat tgatgaaata
    29341 ggctatctgc cgttcagtca ggaagaagca aagctgttct tccaggtcat cgctaaacgt
    29401 tacgaaaaga gcgcaatgat cctgacatcc aatctgccgt tcgggcagtg ggatcaaacg
    29461 ttcgccggtg atgcagcact gacctcagcg atgctggacc gtatcttaca ccactcacat
    29521 gtcgttcaaa tcaaaggaga aagctatcga ctcagacaga aacgaaaggc cggggttata
    29581 gcagaagcta atcctgagta aaacggtgga tcaatattgg gccgttggtg gagatataag
    29641 tggatcactt ttcatccgtc gttgacataa acttatggca tgttgcatta atcaggtaga
    29701 acaaattatc atttttagcg tcagttatag acagctcttt tctggtcaga gtcatcaact
    29761 ttgtagcgta acagtaaaaa agccggcctc accagtcggt ttttttacgt cttttgtatc
    29821 tgcaaaatcc gccccgccat gcccgtcaca ccggggaaac tcatgctctg aacctgaacc
    29881 agccatctca actttgccgt cttctgaaaa aactggcaca ttcagttcga taactaccca
    29941 taaatacaga aagaaaatcc gatgtcagaa aagtggagta aagaattcga ctcttgcttt
    30001 caggtgggga gcatagaaga aattgccgat gctctcgaga aacgcagcgg aagcgaggaa
    30061 aacgcgttag ccatgctggc aatgacagcc ttcacactca tgacccgacg tggtatctgc
    30121 gaaatgcaga acgtggcccc cgatggcaaa ggcattcggc tggagctaat cggcttcagg
    30181 ggaaatgaaa caataccgga tacgcttcat tgaagaagaa agggcgcaat gaggtcagcc
    30241 ttcgcaacaa agcggcggca gaaaacctgc cgccgtgttg cccgttaacg tttaacttcg
    30301 taggctaacg ttgccacaag cactgtgttt ccctgctgga gccggagtac gcaaagcgaa
    30361 tccctcacca tccagacaaa acacagaatc gtcacacaga tgacgattaa catcattaaa
    30421 aacgttcgct gtggcatcat agcccctcca ttgccttacg gcggttatcg ggctactata
    30481 atgttgtcga agcattacag tagagccctt ggttgattga taaaaaaatc tccaggggct
    30541 ttctgctgta taccgtccac aaaacgcttt cggcatacag cctcaagcgc ccgcagctat
    30601 tctaacgact ttcgtatctg caacaatcct tttatcacac ggctaattcc tctggttagc
    30661 tcttatcgcc tgcaaataaa tttttaacct ttccgtttga tttaaattcc agaaatggag
    30721 actttgtcat gtcttacaat cgacagcctg tcgcagaaga tcctatgcag atatggggcg
    30781 ctgttggtgt ccttcttatc ctgctgctat tcgttatatg gttattcttg ccggaagtgg
    30841 tttacgccag ctgcctgatt cttcatacct tatggggact ggttgactgg ggaccatttc
    30901 ataactatgc agcaccacga tacaacctgc ttgccatgac cggtaacaac gccgccaaca
    30961 taagctatag ccagtgggtt aacgtcatgg agcagaccat aggtattctg tggatgtacc
    31021 tcttacctgt gacactctgg tgtttgtggg agtggtatca acatccggga caaagtcgtt
    31081 tcacccgcag accagtagat attacccgcc tgccacacat ctttgcttcg ttgtcccctg
    31141 ctatcgcccc tgtactggca gatggtgatc cggaaaaact ctttcatggt ggcaaacgac
    31201 ctgaacggcg ggttgctctc accccggaag catttgtcga gcagcatact ctcatcacca
    31261 atatgcagct cgatgttgca gctgcaagac gatgtttcat ggcccagtta ggtaaacctt
    31321 taacgtcctg gaaagacatg gcaccacatg aaaaagcgct ctttgccata tttggtcttc
    31381 agtatttcct ggatgatcgt aaggcagcat taaagctcat ggatacactg aacctctcat
    31441 gcagaattaa aagcaaacgg gacagtggga aattctgtac ccctgtttat tcactggcca
    31501 aatcagcttt ccagagagtg attaaaagca acggagcaca gcaatggctg aaacaacatc
    31561 gctacgtccg cagtgggctg gtctggctgt atgcacatga cctgcggctt acgcccccca
    31621 actggatttg gctgaaaggc gtggacagga cgctgtttta tgcattacac cgcgccaata
    31681 ccacgaaagg atttattgaa ggcgctggcg tggtggccgt tgcacgtgca gaggccgaag
    31741 ccatgcgttt tggcctcccc tgccctgaac cctgtgttga tgaagcggtg gaaggcttac
    31801 ggcgggatat gctcagtctc ggtcttatct gggatgaacc acaaccagat cgcgaccgga
    31861 aacgccgcat cctgaccaac tggtccctca ccgacgacat cctgccccgc acacctgcta
    31921 cagacaacga attctgatta tccggagaac tgaaaatgac aatcgagtac tttgcaacac
    31981 gtattgcaaa acatatttcc gtgcaggcaa tctggccgga tggcaggaca gaaattattg
    32041 ccgtccttcc acgggatgcc ctgtcagggc tggtaacacg aaataatcaa ctgattcata
    32101 tagcctttga cgccatgggc acccgtaaca aagaaaccgt cctgattgat aaacaggagc
    32161 ataacgctga ccagatactt acagctattg attcctgcct gcgccttgaa tatctgatgg
    32221 aacgccgctt cagcagaaca cctttgttcc gtggcataat cgccagcgtt gtgctgttcg
    32281 taatggcaac gattggcttc tctctgttcc gctatgttga tcgtgtattc tgggatgata
    32341 caacgcctga agcagtacag acagcaggtg agccacgact gcttccccct cacctgaatc
    32401 acactgtgcc attaaatgaa ggcattcaac tcccggttcc cccgaaaaaa gacgtccagg
    32461 taccggagaa aacaatcaca agcaaaaatc cggaagccgc agctgcgcga cataatctgg
    32521 ctactgttct gaagcggaac gccgatcggg gcatgtttac catcaacctg tcatccggtc
    32581 atgaacgaac cctgttcgca tttctcgatc ctgcctgtcc taactgcaga cttctggagc
    32641 cggccttaaa acgcctggcc agcgacttca atgtcgttat ctacccggtt tcagttattg
    32701 gtggagagga atccaccgac cgtgtggcac cactgctgtg tgaaaaagat gctcagaaac
    32761 gtgctgccgg ctggcaccga ctgtattccg cagataacgg aatgatgacg ccatcagaag
    32821 aaacaacgcc tgcagatgaa acatgcctga aagcagccag agctgcgatt gatgttaaca
    32881 atgtcgcctt ccgtaagttc ggatttgccg gtaccccatg ggtgctgtcc gacacgggct
    32941 ggcatctgcc tactggaatt ctgcaggaaa ctggcacgct taatttattc ctgaaaacca
    33001 ccgacagcga gtctgaccat gagtgaacat cgcgttaacc ccgagctttt acaccgtaca
    33061 gcctggggaa atcctgtctg gaatgcactc cagagtctca atatctatgg cttttgcctg
    33121 gtggcaagtc ttgtggccag ttttatctgg ccacttgcat taccggcatg tctgttgttc
    33181 acactgataa cgatgctggt atttagtctg cagcgatggc gctgccctct tcgtatgccc
    33241 atgacgctgg aatgtgctga cccgtcacag gacagaatga ttaaaagaag ccttttcagc
    33301 ttctggccaa ctctgtttca gtatgaggtc atcctggagt caccggccag cggcatattt
    33361 tatgttggtt atcaacgcgt cagggatata ggtcgggagt tgtggctgag tatggacgat
    33421 ctgacccgcc atataatgtt tttcgccacc accggtggtg gtaaaacgga aaccatcttt
    33481 gcctgggcga ttaacccgct ttgctgggca agaggattca cccttgtcga tggcaaggca
    33541 cagaatgata cggcaagaac gatctggtat ctggccagac gctttggccg tgaagacgat
    33601 gtggaagtca tcaacttcat gaacggagga aaatcccgca gtgaaatcat tctgagtggt
    33661 gaaaaaacac gacctcagtc aaatacctgg aatcccttct gttacagcac tgaggcattc
    33721 acagcggaga caatgcagtc aatgttgccc cagaacgtcc aggggggcga gtggcagtcc
    33781 cgggccattg ccatgaacaa ggcactggta tttggtacta aattctggtg tgtgcgcgaa
    33841 ggcaaaacaa tgtcgctgca gatgctccgt gaacatatga ctctcgaagg gatggccaaa
    33901 ctttactgtc gtggcctcga tgatcagtgg ccggaagaag ctatcgcacc gttacgtaac
    33961 taccttcagg acgttcccgg tttcgacctg tcgctggtca ggacaccatc agcctggacg
    34021 gaagaaccca gaaaacaaca tgcttatctc tccgggcagt tttctgaaac tttcagcaca
    34081 ttcacggaag cattcgggga tatttttgct gaagattccg gtgatatcga tatccgtgac
    34141 agcattcaca gcgacaggat tctgatggta atgatccccg ctctggatac atcagcgcat
    34201 acaacgtctg ctctgggacg aatgtttatc acccagaaaa gtatgattct cgcccgtgat
    34261 ttgggctacc gcctcgaagg aactgattcc gatgcactgg aagtcaaaaa atataagggg
    34321 cgtttccctt atctgtgttt ccttgatgaa gtgggggcat actatacaga ccgtattgct
    34381 gtggaagcca ctcaggtgcg ttcactggat tttgctctga ttttgatggc acaggaccag
    34441 gaacgtatag aaggacagac aacagccacg aatactgcaa cactgatgca gaacacgggg
    34501 acaaaatttg ccggcaggat tgtcagcgag ggcagtacgg ccagaacgct gaaaagcgcc
    34561 gccggtgaag aagccagggc gaggatgaac aacctgcagc gtcaggacgg catatttggt
    34621 gaatcatgga ttgacagccc acaaatcagc atcctgatgg aaagtaagat agatgttcag
    34681 gagttgattg aacttcatcc tggcgagttc ttttctattt tccggggaga aaccgtacca
    34741 tcagcatcat tcttcatccc tgacaatgag aaaagctgca gtagcgatcc cgttgttata
    34801 aacaggtata tcagcgtgga tgcacctcgc ctagaccgtc tccgccgtct ggttccccgt
    34861 acagctcaac gtcgaatacc gtcaccggaa aatgtcagtg ccatcattgg cgtcctgact
    34921 gcaaaaccct ccagaaaaag acgaaaaatt cgcacagagc cgcacacgat cgtggataca
    34981 ttccagcaac gcattgcagg acgtcaggcg gctatggcaa tgctggaaga gtacgacaca
    35041 gatatcaacg cacgtgaaag tgccttgtgg gaaacagcgg taaatacgct taaaacgacc
    35101 acacgggaag agcgacgaat tcgctatatc acgctgaaca gaccagaact acctgaaaca
    35161 aaagaggaaa atcagatatc agtgagagca gaacgagcag gtataaacct gttaacgctt
    35221 ccacaggaca ataaccacct gacagggcgt cctgtaaacg ggtttcatca taaaaaaacc
    35281 aaccgtccgg actgggacgg aatgtactga acagtggccg cgccggattc tggcgcggcc
    35341 ttttttttaa cctggagaag gcggttccca gcgtttatcc tgctccggcg gaggcagtga
    35401 tgcgtcatcg ttgctgttcg ccgcgatata atcgcggtag tagcgttcac ttccttcacg
    35461 gtgatgatcc acgtccggtc gcgtaatcct gtagtcttcg tgaccggtac ggcctgtcac
    35521 attatgccag gcaaccattt cagcaaagac ctggttaaat tgtttgtcgt ttccttctgg
    35581 ttcaaaaccc atgcgtggat cacgcccgaa taataccggt gcaatcaaat ccagtttatc
    35641 tgccagcgca ttgcggtcat ggtgattacg gaaaacaacc ctgtcaccat aatccgtaca
    35701 gacaaactct cccgtccgac ggtcacggaa acgaacactc ccgttcttct gcaaacgggc
    35761 ctcgagatca ccggtattac cgtataccgg cgttccgccc ggttcacaaa gcacgacaca
    35821 gcggtctgtt gtcgttgtgc gtgacttatc tttacggcga tcgcgataat cccagcctct
    35881 cagctgcgat acagcagccc tgtctccctg agcagcctga atttcgaccc actgacggta
    35941 agagggtgga taccacttcc cgtcagcaat aagtttctgc cgctcatccc tgatgtcttc
    36001 tttcagcctg atcaatgcct gcattcgctg aacttctgca atgtgataat gcagcttacg
    36061 taatgccgga tcatcgtact gcgcacgaat gtgtgacttc cgcagacggc atgcctgatg
    36121 aatttcccga caacgttccc cataacgcag atctggttta cgccattgtt cacgccatgc
    36181 cagatagcgg gcacgcaggt cagcacgggc ctcagctctg gcttcacgtc gctgccggcg
    36241 cagcattggg tcacgtttac tgctgacccc gtacctgtca ctgacagcca gctccgggtt
    36301 atagcgactt tcaggttgca ccctgtcaaa caaatctgct ggggcactca caaaaggtcc
    36361 ggcctgtggc tctgcacgcc ccagagtcag atcaggatga atgctgctgg ccttcaccgg
    36421 cgtttgctca tgattaaagg catcaacgac aacaagcccg tgatgttgtt tctgtagcat
    36481 cagtccctgt tgtgcaaaca actcatgaca acgctgccag gtaaactcac cctgtgtgat
    36541 catttcttca atctgagggc tacaatggct gatgctgtat ccccacagac tttctttgtc
    36601 agaaaacagt tcgcgtttga tagccccctg cggccccgta cctgtacgca tacggtgcca
    36661 ttctttatcg gtcgcaggac agctctccat acgacgacca cggaagcgtt ctgttggcgt
    36721 aacctggaga aaaatatctg ttggtacagg ctgccagcca ccatcgagtt gattcacatt
    36781 gtcgagcgtc agcagtgacc atacgctgtc agcacgaacg ggagtctggt tatgatcata
    36841 accgtcacag ataaccaggt gaccatgctg aacacgcatc cataatcccg cttcagccag
    36901 tgtgcggtga atagcctggc agttctccag ccgtccttcc cgtgccattt ccggcagacg
    36961 ttctccaaga tgacgacagg catactgctg cagactttct gtttcagcga ttttttccgg
    37021 gcgaacatca gctgcaatga agtccggatt atagcgtcct ggtgcttcca cctggctgaa
    37081 aatgtctttt ggtactggcg tgtagtcacc catttttttc atgagttttt ctgcacacca
    37141 ggaagggcca aacgagtcaa gctgtacacc ttccctgttg cgatcccagc catccatcac
    37201 cagaaatttt ccgtccatct gagacaggta cagaccatct tcagcaagac gacgatgcag
    37261 ggataaccag tcatgtacag gttcactgcg taaaccagct accgctgtct gcgcaacata
    37321 ctcgcgaaaa gtttgttttt ttccgcgtgt ccaagcgttc tggcgatcac gttcaacggc
    37381 agttttgcga acgatacgat ttcccggcgc atggacccag caaccgttat ccggagcaaa
    37441 accatgcttc agttcaagct cacggcaggc acggctgagt ttttcctgac tccatgaaag
    37501 gcaattgaga taacctgtaa ccggatgcac ccggttgacc gcaacgtgaa catgcaggtt
    37561 atcagtatcg gtatgcacgg cagagacata ctgatgttca cccagcccga gagatttcag
    37621 ggtatggcgt acactgtcat aaatctgttc cggacgcggg ctttcatggg cctgccagga
    37681 aagaatgtag tgaaaaacag gatcagtatt atctttcgca tagtgtgcct gctgtgcaat
    37741 gtactccata tctgcagcgg cagtttcaag cgatgtacag ttgtgaaaac aggtcacacc
    37801 ataaaagtta acccattcgc agccgtcctt catgacatca accagtgcca cgaatgattc
    37861 atttcgaagg cgtgttgcat aatcaacaag acgactgaag cggctccggt gcggttgttc
    37921 agcctgcgaa gaagaagata aattcagttc ctcatcggtc atgtcatccc ggacagagac
    37981 gtaggacacc aggtcttcga acgaagactt gccgtccctt ctctttttcg gaatgactgc
    38041 attcaccgga gaatcctcaa ccttccatta actgtttacg caatgtattt gtaagttcgg
    38101 ttatggcaac aagtacttct gcgtattcct tgtcaccggt tctttttccc tgaacaaaca
    38161 gatgcttctg catccttccc agtctcatta actccttcag aaaagcatca tctgtccggg
    38221 agttaattcg cttattcagt gctgcatttc ggatgtaagc agatacagta agtccggaat
    38281 cttcagcttt tttcctgata gtttcatcct caacaggaga gaatctgagt gtcctgacaa
    38341 ctgtcttttg ccgtacctca cttttctttc ttaccgcact atcactcact tcaggctcct
    38401 tacggggtgt cggggcgaag ccctgaccag atggtaattg taatagcgtc gcgtgtgacg
    38461 gtattacaat tacacatcct gtcccgtttt tcaggccatt atagcctgtt atttttgtgc
    38521 atcatagtct tatgcagacg gcagaggcag ggcgcagccc tgccaggagt cagtttttga
    38581 tgataaaatc agacttcaac atgaaacgga gagaaagtgc caatggcttc taaaaaattt
    38641 tactcagatg atgacatcca gctggcaaaa gctgctttat cggaattgcc agatctcacc
    38701 gctcaacgga aaacattgcg tgattttctt gatgccattc gtgatgacat tattgtcctg
    38761 ataaggacaa agggttatac actggcagat gttcgtgaca cgctcaaaaa tgcagggtat
    38821 gaagtaggag agaaggcact tcgtgacatt attcgggaag cagaatcgaa aaaaccatcc
    38881 cgccgttctt cctctaaaac agcacctaaa aagacagatt caggcaggaa agatggcatc
    38941 gatatgaaca acaattgatg tgacaatgtc acatcgtgtt ctgagattat gatgattaca
    39001 gaaaaaaaag ccccggcata aataccaggg cttttctgtt taatcagact cgtggcggca
    39061 atacacctgg ataatgccgt gcaataatat cattcagttt ttcaacaagg tcagaacgat
    39121 taaagacaat gtgtacggtc cctttctggt agccacgcac cgtaaaatat tccccttcta
    39181 acagcttacc gacattgtcg ccgttcccga gaaattcacc atactgcgcc ccgatgctgt
    39241 tcctgaagtc aggaacgttg cgcccctcca gcagataaaa cggacgtacc aggtcatcca
    39301 gtgcctcccg tccgctgcag tccagcgtca cacgcccgtt actccagcgg tacagcaggt
    39361 tttcaataat gattttctta cccagacggc agggattatt ggttctgtaa tcccatgaca
    39421 atttccggta gacatcaatc agtccctgtt caaatgtctg catcttgcag gcattcagat
    39481 ggcggaatgt tgccagtaca ttgtccaggg tgatttcagg acaggtgtcg ctcatcagct
    39541 ggctgttcca ctcatcacgc tggcatgaac tcatgaaggt gtacatgccc gtatctgtca
    39601 tcaggcgctc ccagattttc cggtcggcaa gacgggtgat attccttttc gcttcttccg
    39661 gtttatctat gcgacgaacg gaatcagtca cgcagtcttc aaacccgtaa agaaaaatat
    39721 cacctgacgc atcgagcaga atcttgcgcg ctgtcgccag gcattccatc gcctgcatga
    39781 acagtgcaat accttcgtta cgctgcgcga tgatgcggtc gatagccaca gacggaataa
    39841 catctgtcgt gccggcagta ttcaggtcag cagtgggtaa agtctgattc atcacattgt
    39901 ctcctcatcg tcacgactgc cgggtcagcc aggtcatttc ccggaggagc gaagctcctt
    39961 ctgccgtccg ggtcttcggg gatttccccg cagtggacct ttccgacggg ggacgctcac
    40021 cacgtcacgg ggcagttgtc cgggggcaga cgcaaaagtt tttgacgcct gcggcaaaaa
    40081 gttttgtggc tggtacatct ctcccctgga cgactgaaac gggatgtggt catgtatgta
    40141 cccccggaaa gtccgtctgc ggagaacagg ccgcagtgcg gcggcagaca ggcagagaca
    40201 gctgcgccat caggcgcagt ggccttacac accgtaaggt gtgcagggag cgccgcatac
    40261 ggcgcgactg aagaaaaacg acggcacaac aatggcatgt ggtggtcact ggcacaccac
    40321 tcccgcacag gtgaaaacag agaaaaccgc acgacattta caagcaaaaa aaagtgaaat
    40381 ttcttcattt ttttacactt atttatcgcg ctgatttggc aattgtgatg ataaaataaa
    40441 gtgaagtttt ttcacttttt caaaggtgtt ttatgaccgg ctgggaactg cgaatctggc
    40501 gaaaaagcat gctctggtca cgcgaaaaag cggccagaga atttggcgtg acgcagagaa
    40561 catggcacgc ctgggaaaat gcggaacagg tggacgtcac cgtctggagg accacccagg
    40621 cactttcagt ccgtgacctg ctgcctcaca tgcaggggat gcgtaaggca gatatcatca
    40681 ggcgactgga aaatgaactg ggggaaacgg cagggaatgt gtgagcgtga ttcacagcct
    40741 ggctgaatgc caggctactg ctcatcagga aacagctttt tcagttcttc accggaaagt
    40801 ccggtcgcct cctgaatccg ttccggcgtc cagcccatat cccgcagccg gcaggctgct
    40861 tcccgcgcca cttcaagcgc acctttctta aaaccttctt taaaaccttc tttaaaacct
    40921 tctttaaaac cttcgtcgaa acctttctgt ataagacgtt ctgcaagcgt catactgttt
    40981 tctctgctcc tgctggcaaa aaagcccggg attttgccgg gctttgcggt tctcatcaat
    41041 gagtgatttt cttcagttcg tcatcggaaa gtccggtagc ctgcttaatc tgctccggcg
    41101 tcatccccat tttctgaagc tggcacgcaa tagccagggc tttttcaagc gcaccttcca
    41161 tcctgccctc ctggcgacct ttttgctcaa gacgttctgc gatagtcatc agtttatcct
    41221 catgctgcgg cagacgctca gccagcgccc gcataaattc cggtgataca gagtcccctg
    41281 cgttaacgat gtaatgaatc agaacacgca cctgctcgtc tgaaatttcc accatgacct
    41341 gcgggagttt gtccagcagc tccatcatgt cacgatggcg gatatgcttc atcagcagcg
    41401 tcagtgcggc catccggcga tggttcatga tttcattgtc atcaacgaca gtgatatcaa
    41461 ccagcggaaa cggatttgtg tatattttag ccgcaagtgc cggattctca aaacagtcca
    41521 gccagttcat gctgtacgga tacgggctgc gctcaccgtg atagaacagc accggaatca
    41581 ccagtggcaa tgttttgtgc tgctccagat gtctctgcat agccgccaca ctgtagcgta
    41641 acatgcgaaa aggcatgtac agattttcgg tgctctggtg ctcgatgagc gtataaacat
    41701 agccgtcttc acccccggtg gttttcacgc tccagaggat atcgctggcg tactgatgca
    41761 ggtccggctc aacaaaggtg gcgggttcca gcttcagcgt ggacaggtcg cacaactgcc
    41821 ggtactccgc aggaagatgc agttccagaa aatccctggc aacgtcggga ttcgccagga
    41881 acgaccggaa cgcggcatca tgcggcgtgg gcgtcgtggt ggttttcttc ttactcacgg
    41941 ttcctcctgg tgagatgtct gaacgtatcc tgccgcctgc acaggcagac ggcaagggtt
    42001 aatcagtggc agacccgctc aatttcaagc gcgcggagca ggtggcccca ttcgctgact
    42061 ttcatggcgg ggatacgtac ccgcttctgc tcactgcagc gtctggcgat atgaccgctc
    42121 atcgccagga cgtccgggtt aatctcatcc tgtgccagct cctgacgtct gaagcgggta
    42181 tggcggtgca ggggtttatt ctcccgcagg cactcttcac gcagacgctt tacatactcg
    42241 gcggttgcga agataattga tggtctcatg gcataatctc catagatagt gattgagatg
    42301 ccggacttcc tggcggggaa gcgccggcgg agagaggcag ggtttatcgc cctgcctttt
    42361 tttcatttcg gacagcgacg cagtgccagc gcgagcgctt tcatcttcca gccttccggc
    42421 gtgcggtaca tcaccttcca gtagccgtcg atgaacacat aatggaagcg cacctcttca
    42481 gtgctttcag tggcaatagc ctccctgaaa gaacggtact cacgcgcctc actgtccatc
    42541 cggaaaccac tgtcacgtcc gtaataagcc gtcacaccgt ccaccgggtt ctgaagcgta
    42601 tgcccggcgg gtttgtcgca acggggaccg aggcaacgga tatcaccgtg ttcaaccagg
    42661 gcttcggcct gctgaccggt ggcatagtgg gtatgcagga tgcgaccgtt ccaggtcggc
    42721 tccccgtgca ggtggcagta aacggtacgg aacaccccgt cgcggcaaaa aacggaaatc
    42781 gtgctgctga ctgtcatgaa aacgtctcct tctgctgaat caggtcgccg ggccgaccgg
    42841 ttgctccccg gaggggcgaa agccccttct gccgtccact tcttcggggt ttctccccgc
    42901 agtggacctt tccgatgggg cgtccgtcac cacgtcacgg ggcagctgtc cgggggcgga
    42961 cgcaaaattt tttgccgggt ttatggctaa aaattttgtg gacggtatat cttcccctgg
    43021 actgctgaaa cgggatgtgg ttactccagc ccccggaaag tccacagcgg gaaacaggcc
    43081 gcaggggtgg cggcggaagg gttgactgcg ccatcaggcg cagtggcctt acacaccgtc
    43141 aggtgtgcag ggagcgccgt ttccggcgcg acaggggcgg cgcgaccgga acggtcgctg
    43201 caagcctggt ttttcagaca tcggaccgta gcggcagccc gaaaccgcgc cagcgggttc
    43261 ggcggagact ggcgggtgcg ccagcagctg cctgtcggag tcgggcctga cgaccggatg
    43321 ccgccaggca gccgggagcc gaagtgggcg caataaaaga cagccagaaa cggtgacagt
    43381 gtcacggaat atcacacctg ttccctgcat acagccatac actacctt
//
LOCUS       DAPHKZ010000026        41898 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.026, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000026 DAPHKZ010000000
VERSION     DAPHKZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41898
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.026"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(130..3279)
                     /gene="acrB"
                     /locus_tag="RH288_001533"
     CDS             complement(130..3279)
                     /gene="acrB"
                     /locus_tag="RH288_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease AcrB"
                     /protein_id="HDV4030603.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHRHTVDHH"
     gene            complement(3302..4495)
                     /gene="acrA"
                     /locus_tag="RH288_001534"
     CDS             complement(3302..4495)
                     /gene="acrA"
                     /locus_tag="RH288_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HDV4030604.1"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     ATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     gene            4637..5284
                     /gene="acrR"
                     /locus_tag="RH288_001535"
     CDS             4637..5284
                     /gene="acrR"
                     /locus_tag="RH288_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HDV4030605.1"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE"
     gene            5412..8777
                     /gene="mscK"
                     /locus_tag="RH288_001536"
     CDS             5412..8777
                     /gene="mscK"
                     /locus_tag="RH288_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HDV4030606.1"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNNTAFARASSNGDLPT
                     KADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEETVQLRQKVAEAPEK
                     MRQATAALTALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLASYNSQLV
                     SLQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQ
                     QRKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSP
                     DEAARIQANPLVKQELEINQQLSQRLITATENGNQLMQQNIKVKNWLERALQSERNIK
                     EQIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDA
                     FVNKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMS
                     VSKNLKSILTQQIFWVNSNRPMDWDWIKAFPQSLKDEFKSMKITVNWQKAWPAVFIAF
                     LAGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCL
                     IILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQT
                     SHWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRE
                     SWRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLAGRWIETVYLVIIWNLLY
                     QTVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLL
                     MFALFGVMFWAIWSDLITVFSYLDSITLWHYNGTEAGAAVVKNVTMGSLLFAIIASMV
                     AWALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQ
                     WLAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTI
                     TDFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEH
                     PRVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIA
                     FNQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     gene            complement(8989..9150)
                     /gene="rsmS"
                     /locus_tag="RH288_001537"
     CDS             complement(8989..9150)
                     /gene="rsmS"
                     /locus_tag="RH288_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HDV4030607.1"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPASTVLRALDIVKRDYEKK
                     LTRDDEAEK"
     gene            complement(9164..9691)
                     /gene="priC"
                     /locus_tag="RH288_001538"
     CDS             complement(9164..9691)
                     /gene="priC"
                     /locus_tag="RH288_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
                     /protein_id="HDV4030608.1"
                     /translation="MKTALLLEKLEGQLATLRQRCAPVSQFATLSARFDRHLFQTRAT
                     TLQACLDEAGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREASAWSLREWDSAP
                     PKIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     gene            9761..10138
                     /locus_tag="RH288_001539"
     CDS             9761..10138
                     /locus_tag="RH288_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HDV4030609.1"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILLILLTFAISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     gene            10291..10842
                     /gene="apt"
                     /locus_tag="RH288_001540"
     CDS             10291..10842
                     /gene="apt"
                     /locus_tag="RH288_001540"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDV4030610.1"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     gene            10971..12902
                     /gene="dnaX"
                     /locus_tag="RH288_001541"
     CDS             10971..12902
                     /gene="dnaX"
                     /locus_tag="RH288_001541"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDV4030611.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEESIRPI"
     misc_feature    12235..12299
                     /gene="dnaX"
                     /locus_tag="RH288_001541"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            12955..13284
                     /locus_tag="RH288_001542"
     CDS             12955..13284
                     /locus_tag="RH288_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDV4030612.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            13284..13889
                     /gene="recR"
                     /locus_tag="RH288_001543"
     CDS             13284..13889
                     /gene="recR"
                     /locus_tag="RH288_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDV4030613.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     gene            13999..15873
                     /gene="htpG"
                     /locus_tag="RH288_001544"
     CDS             13999..15873
                     /gene="htpG"
                     /locus_tag="RH288_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDV4030614.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     gene            16054..16698
                     /gene="adk"
                     /locus_tag="RH288_001545"
     CDS             16054..16698
                     /gene="adk"
                     /locus_tag="RH288_001545"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDV4030615.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIN
                     VDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG"
     gene            16934..17896
                     /gene="hemH"
                     /locus_tag="RH288_001546"
     CDS             16934..17896
                     /gene="hemH"
                     /locus_tag="RH288_001546"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HDV4030616.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPEMPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     gene            complement(17893..18852)
                     /gene="aes"
                     /locus_tag="RH288_001547"
     CDS             complement(17893..18852)
                     /gene="aes"
                     /locus_tag="RH288_001547"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HDV4030617.1"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQYY
                     TLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGSVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     gene            19004..20308
                     /gene="gsk"
                     /locus_tag="RH288_001548"
     CDS             19004..20308
                     /gene="gsk"
                     /locus_tag="RH288_001548"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HDV4030618.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            complement(20441..22117)
                     /locus_tag="RH288_001549"
     CDS             complement(20441..22117)
                     /locus_tag="RH288_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HDV4030619.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGVAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETPPAGEVVTG"
     gene            complement(22355..23575)
                     /gene="fsr"
                     /locus_tag="RH288_001550"
     CDS             complement(22355..23575)
                     /gene="fsr"
                     /locus_tag="RH288_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fosmidomycin MFS transporter"
                     /protein_id="HDV4030620.1"
                     /translation="MAMSEQPQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     gene            23793..25445
                     /gene="ushA"
                     /locus_tag="RH288_001551"
     CDS             23793..25445
                     /gene="ushA"
                     /locus_tag="RH288_001551"
                     /EC_number="3.1.3.5"
                     /EC_number="3.6.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HDV4030621.1"
                     /translation="MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     gene            complement(25482..25961)
                     /gene="ybaK"
                     /locus_tag="RH288_001552"
     CDS             complement(25482..25961)
                     /gene="ybaK"
                     /locus_tag="RH288_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HDV4030622.1"
                     /translation="MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD"
     gene            complement(26165..26959)
                     /locus_tag="RH288_001553"
     CDS             complement(26165..26959)
                     /locus_tag="RH288_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HDV4030623.1"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDITLPGNRHFHLIGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEEQLQNLQHIS
                     QEIGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR"
     gene            27097..27438
                     /locus_tag="RH288_001554"
     CDS             27097..27438
                     /locus_tag="RH288_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HDV4030624.1"
                     /translation="MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSAL
                     INNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
                     ARREERAKKVA"
     gene            complement(27754..30258)
                     /gene="copA"
                     /locus_tag="RH288_001555"
     CDS             complement(27754..30258)
                     /gene="copA"
                     /locus_tag="RH288_001555"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HDV4030625.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEK
                     SVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALV
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLAR
                     AILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNEQQVGTKAIEAEITA
                     QASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKHLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLHNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     gene            30520..31452
                     /gene="glsA"
                     /locus_tag="RH288_001556"
     CDS             30520..31452
                     /gene="glsA"
                     /locus_tag="RH288_001556"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDV4030626.1"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVA
                     IVTCDGNVYSAGDSDYRFALESISKVCTLALALEDVGPQAVQDKIGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENVEQRWQRILHIQQQLAGEQVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLLNTIELATLGATLAAGGVN
                     PLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEDGNSVRGQKMVASVAKQLGYNVFKG"
     gene            31455..32747
                     /locus_tag="RH288_001557"
     CDS             31455..32747
                     /locus_tag="RH288_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV4030627.1"
                     /translation="MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGSLLLSLIVAMVMKRNKTV"
     gene            32872..33279
                     /gene="cueR"
                     /locus_tag="RH288_001558"
     CDS             32872..33279
                     /gene="cueR"
                     /locus_tag="RH288_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HDV4030628.1"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMR
                     DQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     gene            complement(33280..33738)
                     /locus_tag="RH288_001559"
     CDS             complement(33280..33738)
                     /locus_tag="RH288_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDV4030629.1"
                     /translation="MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLVPLGWEWQGVMFAILTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLHIRAVSS"
     gene            complement(33735..34652)
                     /locus_tag="RH288_001560"
     CDS             complement(33735..34652)
                     /locus_tag="RH288_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDV4030630.1"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     gene            34798..35475
                     /gene="fetA"
                     /locus_tag="RH288_001561"
     CDS             34798..35475
                     /gene="fetA"
                     /locus_tag="RH288_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HDV4030631.1"
                     /translation="MQENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNRQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     gene            35462..36241
                     /gene="fetB"
                     /locus_tag="RH288_001562"
     CDS             35462..36241
                     /gene="fetB"
                     /locus_tag="RH288_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HDV4030632.1"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDILWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     gene            complement(36304..37158)
                     /gene="cnoX"
                     /locus_tag="RH288_001563"
     CDS             complement(36304..37158)
                     /gene="cnoX"
                     /locus_tag="RH288_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415025.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HDV4030633.1"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQESNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(37219..38028)
                     /gene="ybbO"
                     /locus_tag="RH288_001564"
     CDS             complement(37219..38028)
                     /gene="ybbO"
                     /locus_tag="RH288_001564"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HDV4030634.1"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPSIAARF
                     TLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMVLKRLLPGRVMDKILQG"
     gene            complement(38018..38641)
                     /gene="tesA"
                     /locus_tag="RH288_001565"
     CDS             complement(38018..38641)
                     /gene="tesA"
                     /locus_tag="RH288_001565"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HDV4030635.1"
                     /translation="MNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSA
                     SAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLR
                     GFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     gene            38612..39298
                     /locus_tag="RH288_001566"
     CDS             38612..39298
                     /locus_tag="RH288_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4030636.1"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     gene            39295..41709
                     /locus_tag="RH288_001567"
     CDS             39295..41709
                     /locus_tag="RH288_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4030637.1"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQMAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGNENQLDGYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSMERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSRYDLVAI
                     LKTLGAGRAQLRKLIVGQWLMVLTLSAVTGGAIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNDVVANVWPLKFYLPIVSVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVAPLKAF
                     LAEHQIVPESFYPVVRARLTAINDKPTEGNEDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKADEVSMEEGLAKRLNVALGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQAKVFDFPWEPDWRLWIVLPCSGALLLSLFGGWLGARLVKGKAL
                     FRQFAG"
BASE COUNT        10004 a        11037 c        11153 g         9704 t
ORIGIN      
        1 atgaatttta tccgtggtta atactggttt tcgtatgaga tcctgagttg gtggttcaat
       61 tactccttaa tgttcgtagg ttatgcataa aaaaggccgc ttacgcggcc ttagtgatta
      121 cacgttgtat caatgatgat cgacagtatg cctgtgctcg atatcttcat tcttgcggct
      181 aaagcggcgg cgaaccacca caaagaatac cggaacgaag aagattgcca gtaccgttgc
      241 ggtcaccatc ccgcccatta caccggtacc tactgcgttc tgcgcgccgg aaccagcacc
      301 agtactgata accagcggca taacgccgag gataaacgcc agcgaggtca tcaggatcgg
      361 acgtaaacgc atccgcaccg catcaagcgt cgcttcaatc agacctttac cttctttatc
      421 catcaagtct ttggcgaatt cgacgataag gatcgcgttc ttcgccgaca acccaatggt
      481 tgtgagcagg cctacctgga agtaaacgtc attggtcagg ccacggaagg tggcagccag
      541 caacgcaccg ataaccccca gcggaacgac cagcataacg gagaacggaa tcgaccagct
      601 ctcgtacagc gccgccagac acaggaacac gacaatcaac gaaatcgcgt acagtgaagg
      661 tgcctggttg ccggagagac gttcctgata ggacatcccc gtccagtcat agccaacacc
      721 ggtaggcagt ttgctcgcca gttgttccat cagctccatt gcttcaccgg tacttttacc
      781 cggtgccgcc tggcctaaga tttccatgga tggcaggccg ttgtaacgtt ccagacgcgg
      841 cgaaccgtac tcccaacgag aagaggagaa cgccgagaat ggcaccatct gaccatcagc
      901 agcacgaaca taccagtcgc cgatatcatc cggcagcata cggtatttcg cttctgacat
      961 gacataaact ttcttcacac gaccgcggtc gataaagtcg ttcacatagc tgccgcccca
     1021 tgcagcgccc agagtggtgt taatgtcgtt gatagaaaca cccagcgcct gcgctttttc
     1081 ctggtcgata tcaatcttaa actgcggggt atcttccaga ccgtttggac gtacgctggt
     1141 caacatatca gggtgcttcg ctgcttctgc aagcaactgg ttacgcgcct gagtcagttt
     1201 ttcgtgacca aggccagcct ggtcaatcag ctcaaagtca aagccggttg cagtacccag
     1261 ttccacgatt gcgggcaggt taaaggcgaa aaccatcgca tctttgattt gcgagaaagc
     1321 gcgtgttgca cgcatggtaa tcgcttcaac tttgttttct tcgcccggac gatcggccca
     1381 gtccttcaag gaaacgaacg caataccggt attctgacca cgtcccgcaa agccgaagcc
     1441 gttaacggcg aacaccgact caacgttgtt cttttctttg gtcagatagt aatgcgttac
     1501 ctcattgagc actttctgtg tacgttcctg cgttgcacct gctggcagct gaaccatggt
     1561 cataaacacg ccctggtcct catctggcaa gaaggagctt ggcagacgca cgaacagata
     1621 ggccatgccg accacgatga tcagatacag caccaggtaa cgccccgtac tgcgcagaat
     1681 accgcctacg ctgtcggtgt agtggtgcgt gctcttctcg aacatgcggt taaaccagcc
     1741 gaagaagcct tttttacctt ccccgtgatc gcctttggca atcggtttca gcatggtggc
     1801 acaaagagct ggagtcagga tcaacgccac cagtaccgac agcgccattg ctgaaacaat
     1861 ggtaatagag aactgacgat agatagcacc agtagaaccg ccaaagaagg ccatcggtac
     1921 gaataccgcc gacagtacca tcgcgatacc gaccagagcg ccctgaatct gccccatcga
     1981 cttacgggta gcttcttttg gcggcaaacc ttcttccgcc ataacacgct caacgttttc
     2041 taccacaacg atggcgtcat ccaccaacag gccgatggcg agcaccatcc cgaacattgt
     2101 tagcgtgttt atcgagaagc caaaggcggc aaggacggca aaggtcccga gcaataccac
     2161 cggtacggca atggtcggaa tcaacgtcgc gcggaagttc tgcaggaaca gatacataac
     2221 caggaacacg aggatgatcg cttcgaccag cgttttaacc acttcgtgaa tagagatttt
     2281 cacgaacggc gtggtgtcgt atgggtaaac aattttcaga cccgacggga agaacggttc
     2341 catcttcgcc agttcagcac ggattgccgc agcggtatcc agcgcgtttg caccggtcgc
     2401 cagcttgatc cccagaccgg aagccggttg gccgttaaac tctgcgatga tgtcgtagtt
     2461 ctcaccaccc agctcaatct tcgcgacgtc acgcagcagc acgcgggaac catcctgatt
     2521 cactttcagc aggattttgc cgaactcttc agtagaggtc agacgcgtct gagcaataat
     2581 agaggcgtta agctgttggc ctttcaccgg cggcgtacca ccgagctgac ccgccgcaac
     2641 ctgggcgttc tgcgctttga tggcggtaat gacatcaacc ggcgttagct ggaatttgtt
     2701 cagctcattc gggttcatcc agatacgcat cgcgtactgt gaaccgaaca actgaacatc
     2761 acccacgccc gacgtacggc tgatggcatc tttcatattc gccgccacgt agtcggagat
     2821 atcctcctgc gtcatggtgc catcggtgtt gataacgccg acaaccatca ggaagctgct
     2881 ggatgatttc tcaacgctca ccccttgctg ctgaacttct tgcggcagca acggcatcgc
     2941 cagctgcagt ttgttctgca cctgaacctg cgcgatatcc gcatcagtac cagactcaaa
     3001 ggtcagggtg atctgcacgg tacccgtgga gtcactgtta gaggacatgt acatcaggtt
     3061 atcgataccg ttcatattct gttcgataac ctgtgtcacc gtgtcctgca ctgttttcgc
     3121 atcagcgccg gggtaggagg cggagatcgt tactgccggc ggtgcaatcg taggatattg
     3181 cgccaccggc agtttgagga tcgccagccc ccctgccaac atgatgataa tggcgatcac
     3241 ccacgcaaaa atcgggcgat cgataaagaa attaggcatg tcttaacggc tcctgtttaa
     3301 gttaagactt ggactgttca ggctgagcac cgcttgcggc ttgctggtta ttatcagcgg
     3361 taacttcttg tgcttttacc tggacaccag gacgcacttt ctgcagccca cttattacta
     3421 cgcgatcgcc tgctttcaga ccttctgtca ccagccactt atcgccaata gcctggcttg
     3481 caacgatcgg acgggtttcc actttgtcat ccgcgccaac taccagtacg gtggcatcgc
     3541 cacgcggcgt acgggttacg ccctgttgcg ggactaaaat agcgtttgga ttaagccctt
     3601 cttccagacg tgcgcgcacg aacatacccg gcagcagagt gtgatccggg ttcgggaaga
     3661 tagcgcgtag ggtgatagac ccagtggtct gatcaacggt aacgtcagag aattccagcg
     3721 taccgtcctg cgggaactta atgccgtcac tggtgatcag tgacactttg gctttgccgt
     3781 tctcttgttt cagcgtgcca ttcgccagtt cctgtttcag gcgcaggaag tcgttgctgg
     3841 actgggtcac atcaacgtag atcggatcaa gttgctgcac ggttgccagc gcagtcgcct
     3901 gaccgttctg taccaatgcg ccttccgtca cgttcgactt accaatgcga ccgctaatcg
     3961 gagaggtgac tttggtgtaa gccagattga tccgcgcagt ttcaacggca gctttcgccg
     4021 cagttaccgc agcattcgcc tgttgcgcat cagccagagc ctgatcgtac tcttgcttac
     4081 tgatgtactg agtaccgagc agtttctgat aacgattcac cgtcaattgc gcgatattgg
     4141 ctgcagcctg ggctttcgcc agatcacctt tcgcactgtc gtatgtcgcc tgataggtcg
     4201 caggatcaat ctgatagaga gagacacctg cttcgatgtc gctaccttct ttgaaattac
     4261 gcttcaggat aatcccgcta acttgaggac gaacttctgc gatccggtag gcactggtgc
     4321 gacccggaag ctcggttgtg atctgcagag gttcagtttt gactgttact acgccaacgg
     4381 cgggcatctg ctggccacct tgttgggcct gtttgtcgtc acatcctgtt agggctaagc
     4441 tgcctgagag catcagaacg accgccagag gcgtaaaccc tctgtttttg ttcatatgta
     4501 aacctcgagt gtccgatttc aaattggtca atggtcaaaa gttaataaac ccattgctgc
     4561 gtttatatta tcgtcgtgct atggtacata cattcacaaa tgtatgtaaa tctaacgcct
     4621 gtaaattcac gaacatatgg cacgaaaaac caaacaagaa gcgcaagaaa cgcgccaaca
     4681 catcctcgat gtggctctac gtcttttctc acagcagggg gtatcatcca cctcgctggg
     4741 cgagattgca aaagcagctg gcgttacgcg cggtgcaatc tactggcatt ttaaagacaa
     4801 gtcggatttg ttcagtgaga tttgggaact gtcagaatcc aatattggtg aactagagct
     4861 tgagtatcag gcaaaattcc ctggcgatcc actctcagta ttaagagaga tattaattca
     4921 tgttcttgaa tccacggtga cagaagaacg gcgtcgatta ttgatggaga ttatattcca
     4981 caaatgcgaa tttgtcggag aaatggctgt tgtgcaacag gcacaacgta atctctgtct
     5041 ggaaagttat gaccgtatag aacaaacgtt aaaacattgt attgaagcga aaatgttgcc
     5101 tgcggattta atgacgcgtc gcgcagcaat tattatgcgc ggctatattt ccggcctgat
     5161 ggaaaactgg ctctttgccc cgcaatcttt tgatcttaaa aaagaagccc gcgattacgt
     5221 tgccatctta ctggagatgt atctcctgtg ccccacgctt cgtaatcctg ccactaacga
     5281 ataaccctga atctgactcc aggatttttc ctggacattt tcgtcgttgc tattctggtt
     5341 cactgcgtcg tgatattctt gcggtttgac tttttcaggt cgttcttcag gttcagaaac
     5401 cttcattcat catgactatg ttccagtatt acaaacgatc acggcatttt gttttttcag
     5461 catttattgc ttttgttttt gtcttgttat gccagaacaa cacggcgttt gcgcgggcgt
     5521 catcgaatgg tgatctgccg acaaaagcgg acctgcaggc gcaacttgac tcactaaata
     5581 aacaaaaaga tctttctgct caggacaaac tggtgcagca ggatctgaca gatacattag
     5641 ccaccctcga taaaatcgat cgcataaaag aagagacagt tcagctacgg caaaaagtcg
     5701 ctgaagcgcc ggaaaaaatg cgccaggcga ccgcggcgtt aacagcactt agcgatgtcg
     5761 ataacgacga agaaacgcgc aaaattctga gcacgctgtc gttgcgccag ctggaaactc
     5821 gcgttgccca ggcgctggac gatttgcaaa acgcacaaaa cgatctggcg tcttataaca
     5881 gccagctggt ttcgttacag acgcagcccg aacgcgtgca aaatgcgatg tataacgctt
     5941 cgcagcagct gcaacaaatt cgcagtcgtc tggatgggac tgatgtcggc gagacagcct
     6001 tacgtcccag ccagaaagtg ttaatgcagg cccagcaggc gttgctgaat gcggagattg
     6061 accagcagcg taaaagcctg gaagggaaca ccgtcttgca ggataccttg caaaagcaac
     6121 gtgattacgt gacggcgaac agcgctcgtc tggagcacca gttacaactg ttgcaagaag
     6181 cggtaaacag caagcgcctg actttaaccg aaaaaacggc gcaggaagcc gtctccccgg
     6241 atgaagccgc gcgtattcag gctaatccgc tggtgaagca ggaactggaa attaaccagc
     6301 agttaagtca gcgtctgatt accgcgactg aaaacggtaa tcagttgatg cagcaaaaca
     6361 ttaaagtcaa aaactggctg gagcgggcgc tgcaatcgga acgcaatatt aaagagcaga
     6421 ttgccgtcct gaagggcagc ctgctgttgt ctcgtatcct ttaccagcaa caacaaacgc
     6481 tgccctcggc ggatgaactg gaaaacatga ccaaccgcat cgcggatttg cgtctcgaac
     6541 agtttgaagt taaccagcag cgtgatgcac tcttccagag cgatgcgttc gtcaacaaac
     6601 tggaagaagg tcacaccaac gaagtcaaca gcgaagttca cgatgcgtta ttgcaagtgg
     6661 ttgatatgcg tcgcgaattg ctggatcaac tcaacaaaca gttgggtaac cagctgatga
     6721 tggccattaa cctgcaaatc aaccagcagc agttaatgag tgtgtcgaaa aacctgaaat
     6781 ccatcctgac tcagcaaatc ttttgggtga acagtaaccg tccaatggac tgggactgga
     6841 tcaaagcgtt cccgcaaagc ctgaaagatg aatttaagtc gatgaaaatc acggtgaact
     6901 ggcaaaaagc ctggcccgcc gtttttatcg ctttcctcgc tggtttgccg ctgctgttga
     6961 ttgccgggct gatccactgg cgtctgggct ggctgaaagc gtatcaacaa aaactggctt
     7021 ccgctgtggg ttccctgcgt aacgacagcc agctcaacac accaaaagcg atccttatcg
     7081 acctgatccg tgcgctgccg gtgtgcctga ttattctcgc ggttggcctg attctgttga
     7141 ccatgcagct caacatcagc gaactgctat ggtcgttcag caaaaaactg gcgatattct
     7201 ggctggtgtt tggcctgtgc tggaaggtac tggagaaaaa cggcgttgcc gtacgtcact
     7261 tcggcatgcc ggaacagcag accagccact ggcgtcggca aattgtccgc atcagtctcg
     7321 cattgctgcc tatccatttc tggtctgtgg tggcagaact ttccccgctg catctgatgg
     7381 atgatgtgct ggggcaagcg atgattttct tcaacctgct gctgattgcc ttcctggtat
     7441 ggccgatgtg ccgcgaaagc tggcgtgata aagagtcgca caccatgcga ctggtcacca
     7501 ttaccgtgct gtcgataatc ccgattgcgc tgatggtgct gactgctaca ggctacttct
     7561 acactacgct gcgtctggca ggacgctgga ttgaaaccgt ttatctggtg atcatctgga
     7621 acctgctgta ccagacggta ctgcgtggct taagcgtagc ggcgcggcgt atcgcctggc
     7681 gtcgtgcgct ggcgcgtcgg cagaatctgg tgaaagaggg tgcagaaggt gctgaaccgc
     7741 cggaagaacc caccattgca ctggagcaag ttaaccagca gacgctgcgt attaccatgt
     7801 tgctgatgtt tgcgctgttc ggtgtcatgt tctgggcaat ttggtccgat ttgatcaccg
     7861 tgttcagcta tctcgacagc atcacgctct ggcattacaa cggcactgaa gctggcgctg
     7921 cggtggtgaa aaacgtcacc atgggcagtc tgttgtttgc gattatcgcc tcaatggtgg
     7981 cctgggcgtt gattcgcaac ctgcctggtt tactggaagt gctggtgctc tcgcgactga
     8041 atatgcgcca gggcgcgtcg tatgccatta ctaccatcct taactacatc attattgctg
     8101 ttggtgcgat gacggtgttc ggatcgctgg gcgtctcttg ggataaactc cagtggctgg
     8161 ccgcagcatt atccgtaggt cttggttttg gtttacaaga aattttcggt aacttcgtct
     8221 ccggtttgat cattctattc gaacgtccgg tgcgtattgg cgatacggta accattggta
     8281 gcttctcggg gacggtaagt aagatccgta ttcgtgcgac aacgattacc gatttcgatc
     8341 gcaaagaagt gatcatcccg aacaaagcgt ttgttaccga gcgtctgatc aactggtcgt
     8401 tgactgacac tactacgcgt ctggtgatcc gtctcggcgt ggcctatggc tccgatctgg
     8461 aaaaagtgcg taaagtgtta ctgaaggcgg cgactgagca cccaagggtg atgcacgaac
     8521 caatgccgga agtcttcttt acggcatttg gtgccagcac gttggatcat gagctgcgtc
     8581 tgtatgtgcg tgaactgcgt gaccgtagtc gtactgtcga tgagctgaac cgtactatcg
     8641 atcagctgtg ccgtgaaaac gacatcaaca ttgcctttaa ccagcttgaa gtgcatctgc
     8701 acaacgagaa gggcgatgag gtgacggaag taaaacgcga ctacaaaggc gatgacccga
     8761 cgccagcggt agggtaaaaa cgaaaggggg caacatttag ttgccccgag attgctaaca
     8821 aagtgcgcgt tgttcatgcc ggatgcggcg tgaccgcctt atccggccta cgaaaccgca
     8881 agaattcaat atattgcagg agcggtgtag gcctgataag cgtagcgcat caggcagttt
     8941 tgcgtttgcc cgcaacctta ggggacattt agcgacccca tttatttctc acttttccgc
     9001 ctcatcatcg cgcgttaatt tcttttcata atcacgcttt acaatatcca gcgcgcgcag
     9061 cacggtactg gccgggatct gattttcctc cagcagcaca atcaaatcga cagccagttt
     9121 gacatcgtca ggggcatttt ccagtgacat attctctcca ttgctagcgg gttaaacgcg
     9181 ctaacctgtt ttcgattttt tccagcgcat ggcggcagcg tgccaggcgc gcttcatagg
     9241 cttccacttc acgatgcagc gtttgctgtt ccacgagatc ggtcacccgc gccagacggg
     9301 ctctgcgttc ggcaaccatc tcacgtagcc gccgctcaaa atcctgatgc tgaatacgtt
     9361 tacgctgcca gcgggcaatt ttcggtggtg cactgtccca ctcgcgcaat gaccaggcgg
     9421 aggcttcacg cgcgatggct tccagttgtg ccgccagatg ttccgccagc caggccactt
     9481 gcggcagctg ttgctgctca actgcatgac gaagcgcagc cagattatcg cccgcctcgt
     9541 cgagacaagc ctgtagtgtt gtcgcacgag tctgaaaaag atgcctgtcg aaacgagcac
     9601 ttagcgtggc gaactgtgac accggggcac aacgctgacg cagcgtagcg agctgtcctt
     9661 ccagtttttc cagcagcagg gcggttttca cgataagacc tcaatgaaaa tgataattgt
     9721 tatgctaaag tagccactct gtaagctgac aacactcaat atgcaacgaa tcattttaat
     9781 catcattggc tggctggcgg tagtgctggg tacgctgggc gtggtattac cggtattacc
     9841 gacgacgccg tttatcctgc tggcggcctg gtgctttgcc cgttcttccc cgcgctttca
     9901 cgcctggttg ctgtaccgct catggtttgg cagctatcta cgtttctggc agaaacatca
     9961 tgcgatgccg cgcggcgtca aaccgcgggc gattttgctt attttgctca cgtttgccat
    10021 ttctctgtgg ttcgtccaga tgccatgggt gcgcatcatg ttgctggtaa ttctcgcctg
    10081 tttgcttttc tatatgtggc gaattccggt gattgatgaa aagcaagaaa agcactgaag
    10141 cacaacaatc gcagttgcaa ttattgcgta cagccagtac attctggcgt tttcgagcac
    10201 aggcgcaggc ggtcaaaggt taaacaactg ttacttttga tacgtttaaa acgcgccgtg
    10261 agtaccaccg taacaagcag gcatacactt atgaccgcga ctgcacagca gcttgagtat
    10321 ctcaaaaata gcatcaaaag cattcaggac tacccaaaac ccggcattct tttccgcgat
    10381 gtcaccagct tactggaaga cccgaaagct tacgctctca gcatcgactt gctggttgag
    10441 cgttacaaaa atgcgggcat taccaaagtt gtcggcaccg aagcgcgtgg cttcttgttt
    10501 ggcgctccgg tagctctggg tctgggcgtt ggctttgtac cggtccgtaa accgggcaaa
    10561 ctgccgcgtg aaaccatcag tgaaacttac gacctggaat acggcaccga tcagctggag
    10621 atccacgttg atgccatcaa accgggcgac aaagttctgg tggtggacga cctgctggca
    10681 accggcggca ctatcgaagc gaccgttaaa ctgatccgtc gtctgggtgg tgaagtggct
    10741 gacgctgcgt tcattatcaa cctgttcgat ctcggcggcg aacagcgtct cgaaaaacag
    10801 ggcattacca gctacagcct tgtcccgttc ccgggccatt aattatcgcc agtcttgtgc
    10861 tgcccacgct acggacagca caagatgtgc attcagcctc gccgttctga cggggctgtg
    10921 ttagcattac cccttcgtga atccaccttc cagcgtttca gagcctgcca atgagttatc
    10981 aggtcttagc ccgaaaatgg cgcccacaaa cctttgctga cgtcgtcggc caggaacatg
    11041 tgctgaccgc actggcgaac ggcttgtcgt tagggcgtat tcatcatgct tatctttttt
    11101 ccggcacccg tggcgtcgga aaaacctcta tcgcccgact gctggcgaag gggctaaact
    11161 gcgaaaccgg cattaccgcg acgccgtgcg gcgtgtgcga taactgtcgt gaaatcgagc
    11221 aggggcgctt tgtcgatctg attgaaatcg acgccgcctc gcgcaccaaa gttgaagata
    11281 cccgcgacct gctggataac gtccagtacg ctccggcgcg tggtcgtttc aaagtttatc
    11341 tgatcgacga agtgcatatg ctgtcgcgcc acagctttaa cgcactgtta aaaacccttg
    11401 aagagccgcc ggagcacgtt aagtttctgc tggcgacgac cgatccacag aaattgccgg
    11461 tgacgatttt gtcacgctgt ctgcaatttc atctcaaggc gctagatgtc gagcaaattc
    11521 gccatcagct tgagcacatc ctcaacgaag aacatatcgc tcacgagccg cgggcgctgc
    11581 aattgctggc acgcgccgct gaaggcagcc tgcgagatgc cttaagtctg accgaccagg
    11641 cgattgccag cggtgacggc caggtttcaa cccaggcggt cagtgcgatg ctgggtacgc
    11701 ttgacgacga tcaggcgctg tcgctggttg aagcgatggt cgaggccaac ggcgagcgcg
    11761 taatggcgct gattaatgaa gccgctgccc gtggtatcga gtgggaagcg ttgctggtgg
    11821 aaatgctcgg cctgttgcat cgtattgcga tggtacaact ttcgcctgct gcacttggca
    11881 acgacatggc cgccatcgag ctgcggatgc gtgaactggc gcgcaccata ccgccgacgg
    11941 atattcagct ttactatcag acgctgttga ttggtcgcaa agaattaccg tatgcgccgg
    12001 accgtcgcat gggcgttgag atgacgctgc tgcgcgcgct ggcattccat ccgcgtatgc
    12061 cgctgcctga gccagaagtg ccacgacagt cctttgcacc cgtcgcgcca acggcagtaa
    12121 tgacgccaac ccaggtgccg ccgcaaccgc aatcagcgcc gcagcaggca ccgactgtac
    12181 cgctcccgga aaccaccagc caggtgctgg cggcgcgcca gcagttgcag cgcgtgcagg
    12241 gagcaaccaa agcaaaaaag agtgaaccgg cagccgctac ccgcgcgcgg ccggtgaata
    12301 acgctgcgct ggaaagactg gcttcggtca ccgatcgcgt tcaggcgcgt ccggtgccat
    12361 cggcgctgga aaaagcgcca gccaaaaaag aagcgtatcg ctggaaggcg accactccgg
    12421 tgatgcagca aaaagaagtg gtcgccacgc cgaaggcgct gaaaaaagcg ctggaacatg
    12481 aaaaaacgcc ggaactggcg gcgaagctag cggcagaagc cattgagcgc gacccgtggg
    12541 cggcacaggt gagccaactt tcgctaccaa aactggtcga acaggtggcg ttaaatgcct
    12601 ggaaagagga gagcgacaac gcagtatgtc tgcatttgcg ctcctctcag cggcatttga
    12661 acaaccgcgg tgcacagcaa aaactggctg aagcgttgag catgttaaaa ggttcaacgg
    12721 ttgaactgac tatcgttgaa gatgataatc ccgcggtgcg tacgccgctg gagtggcgtc
    12781 aggcgatata cgaagaaaaa cttgcgcagg cgcgcgagtc cattattgcg gataataata
    12841 ttcagaccct gcgtcggttc ttcgatgcgg agctggatga agaaagtatc cgccccattt
    12901 gatcgtaagc acagcttacg ttcgtcatcc ttaacgtgat tgagagagaa acctatgttt
    12961 ggtaaaggcg gtctgggtaa cctgatgaag caagcccagc agatgcaaga aaaaatgcag
    13021 aaaatgcagg aagagatcgc gcagctggaa gtcaccggcg aatctggcgc aggtctggta
    13081 aaagtgacca tcaacggtgc acacaactgc cgtcgcgtag agatcgaccc gagcctgctg
    13141 gaagacgaca aagagatgct ggaagacctg gtggctgcag cattcaacga cgcagcacgt
    13201 cgtattgaag aaacgcagaa agaaaaaatg gcctctgtat cctccggaat gcagctgccg
    13261 cctggcttta agatgccgtt ctgatgcaaa ccagcccgct gttaacacag cttatggaag
    13321 cactgcgctg tctgccgggc gttggcccga agtcggcgca gcgtatggcg ttcacgctgc
    13381 ttcagcgcga tcgtagcggc gggatgcgtc tggcgcaggc gctcacccgg gcgatgtcgg
    13441 aaatcggcca ctgcgccgat tgccgcactt tcaccgaaca ggaagtctgt aacatctgtt
    13501 cgaatccgcg tcgtcaggaa aacggtcaaa tctgcgtggt ggagagcccg gcggacatct
    13561 acgccattga gcagacgggg cagttttcag gtcgttattt tgtgttgatg gggcatctgt
    13621 caccgctgga cggcatcggt ccggatgata tcgggcttga tcgtctggaa cagcgtctgg
    13681 cagaggaaaa aatcactgaa gtgatcctcg ccaccaaccc cacggttgaa ggtgaagcta
    13741 ccgctaacta cattgccgag ctttgcgcgc aatatgacgt ggaagccagc cgaatcgctc
    13801 atggcgttcc ggttggcggc gagctggaaa tggtcgacgg caccacgttg tcacactccc
    13861 ttgccgggcg tcataagatt cgtttttaag caaacgagag caggatcacc tgctctcgct
    13921 tgaaattatt ctcccttgtc cccatctctc ccacatcctg tttttaacct taaaatggca
    13981 ttattgaggt agacctacat gaaaggacaa gaaactcgtg gttttcagtc agaagtgaaa
    14041 cagcttctgc acctgatgat ccattctctc tattccaata aagaaatctt cctgcgtgag
    14101 cttatctcta acgcctccga tgcggcggac aagctgcgtt tccgtgcgct ctctaacccg
    14161 gacctgtacg aaggtgatgg cgaactacgc gttcgtgtct ctttcgataa agacaagcgt
    14221 acgctgacca tctccgataa cggcgtgggg atgacccgcg acgaagtgat tgaccatctg
    14281 gggactatcg ctaaatccgg taccaaatca ttcctcgaat ccctgggttc tgaccaggcg
    14341 aaagacagcc agctgatcgg tcagtttggt gttggtttct actctgcgtt tatcgtggcc
    14401 gacaaagtga ccgtgcgtac tcgcgcggca ggcgaaaaac cagaaaatgg cgtcttctgg
    14461 gaatcggctg gcgaaggtga atacaccgtt gccgacatca ccaaagaaga tcgtggtact
    14521 gaaatcaccc tgcatctgcg tgaaggcgaa gacgagttcc tcgatgactg gcgcgtgcgt
    14581 tccatcatca gcaaatactc cgaccatatc gcgctgccgg tagagatcga aaaacgcgaa
    14641 gagaaagacg gcgaaaccgt tatctcctgg gagaaaatca acaaagcgca ggcgctgtgg
    14701 actcgtaaca agtcggaaat caccgatgaa gagtacaaag agttctacaa acacatcgcc
    14761 cacgacttta atgatccgct gacctggagc cacaaccgtg ttgaaggtaa gcaggagtac
    14821 accagcctgc tgtacatccc gtcccaggct ccgtgggata tgtggaaccg cgatcataaa
    14881 cacggcctga aactgtatgt tcagcgtgtg ttcatcatgg acgacgcaga acagttcatg
    14941 ccgaactatc tgcgcttcgt gcgtggtctg attgactcca gcgatctgcc gctgaacgtt
    15001 tcccgtgaaa tcctccagga cagcacggta acgcgtaacc tgcgcaatgc gctgaccaag
    15061 cgtgtgctgc aaatgctgga aaaactggcg aaagacgacg cggaaaaata ccagaccttc
    15121 tggcaacagt ttggcctggt actgaaagaa ggtccggcgg aagatttcgc taaccaggaa
    15181 gcgatcgcca aactgctgcg ttttgcttct acccataccg attcttctgc gcagaccgta
    15241 tctctggaag actacgtttc ccgcatgaaa gaagggcagg agaaaatcta ctacatcacc
    15301 gcagacagct atgcggcagc gaagagcagc ccgcacctgg aactgctgcg taagaaaggc
    15361 atcgaagttc tgctgctttc cgaccgcatc gatgagtgga tgatgaacta tctgactgag
    15421 ttcgacggta aaccgttcca gtcggtgtct aaagttgacg agtcgcttga aaaactggct
    15481 gacgaagttg atgagagcgc gaaagaagcg gagaaagcac tgactccgtt catcgaccgt
    15541 gtgaaagccc tgctcggcga gcgcgtgaaa gatgtccgtc tgactcaccg tctgaccgat
    15601 acgccagcga tcgtttcgac cgacgcggac gaaatgagca ctcagatggc gaaactgttc
    15661 gctgcggcgg gccagaaagt gccagaagtg aaatacatct tcgaactgaa cccggatcac
    15721 gtactggtga aacgtgcggc agatactgaa gatgaagcga agttcagcga gtgggtagaa
    15781 ctgctgctgg atcaggcgct gctggcagaa cgcggcacgc tggaagatcc gaacctgttt
    15841 attcgtcgta tgaaccagct gctggtttcc tgatgtaatg ccggatgacc ttcgtgtcat
    15901 ccggcatttt tcttttcatc atctgcactt tccgcaaatt atctcgccat taaccgtttc
    15961 agccccaggt gcctttcttg aggcaatcgc ctgttggtgg tatcgtttat cgctttttca
    16021 aaaaattcga cacattttaa ggggattttc gcaatgcgta tcattctgct tggcgctccg
    16081 ggcgcgggga aagggactca ggctcagttc atcatggaga aatatggtat tccgcaaatc
    16141 tccactggcg atatgctgcg tgctgcggtc aaatctggct ccgagctggg taaacaagca
    16201 aaagacatta tggatgctgg caaactggtc accgacgaac tggtgatcgc gctggttaaa
    16261 gagcgcattg ctcaggaaga ctgccgtaat ggtttcctgt tggacggctt cccgcgtacc
    16321 attccgcagg cagacgcgat gaaagaagcg ggcatcaatg ttgattacgt tctggaattc
    16381 gacgtaccgg acgaactgat cgttgaccgt atcgtcggtc gccgcgttca tgcgccgtct
    16441 ggtcgtgttt atcacgttaa attcaatccg ccgaaagtag aaggcaaaga cgacgttacc
    16501 ggtgaagaac tgactacccg taaagatgat caggaagaga ccgtacgtaa acgtctggtt
    16561 gaataccatc agatgacagc accgctgatc ggctactact ccaaagaagc agaagcgggt
    16621 aataccaaat acgcgaaagt tgacggcacc aagccggttg ctgaagttcg cgctgatctg
    16681 gaaaaaatcc tcggctaatt cgaaagcgcg cacggacagt cccctcgccc cctcggggag
    16741 agggttaggg tgaggggaac aggcccgcac aagcaaactt atcagcaatc tcaggccgga
    16801 tattcattcg gccttttaca aaaacctcaa tctgcgctat tcctttttct gatttgacct
    16861 ctcacagcaa ttagttcttc ttcctcactt ttccgctaca attatcaaca agttgaatcg
    16921 ataagaggcg gtaatgcgtc agactaaaac cggtatcctg ctggcaaacc tgggtacgcc
    16981 cgatgccccc acacctgaag cggtaaaacg ctatctgaaa caatttttaa gcgacagacg
    17041 cgtggttgat acctcacggt tgttatggtg gccattgctg cgcggcgtga ttttgccgct
    17101 gcgctcgccg cgtgtggcga agctgtatgc ctctgtctgg atggaaggtg gctcgccgct
    17161 gatggtttac agccgccagc aacagcaggc gctggcacaa cgtttaccgg agatgcccgt
    17221 agcgctggga atgagctacg gctcgccatc actggaaagc gccgtagatg aactcctggc
    17281 agagcatgta gatcatattg tggtgctgcc gctttatccg caattctcct gttctacggt
    17341 cggtgcggta tgggatgaac tggcacgcat tctggcgcgc aaacgtagca ttccggggat
    17401 atcgtttata cgtgattacg ccgataacca cgattacatt aatgcactgg cgaacagcgt
    17461 acgcgcttct tttgccaaac atggcgaacc ggatctgcta ctgctctctt atcatggcat
    17521 tccccagcgt tatgcagatg aaggcgatga ttacccgcaa cgttgccgca caacgactcg
    17581 tgaactggct tccgcattgg ggatggcacc ggaaaaagtg atgatgacct ttcagtcgcg
    17641 ctttggtcgg gaaccctggc tgatgcctta taccgacgaa acgctgaaaa tgctcggaga
    17701 aaaaggcgta ggtcatattc aggtgatgtg cccgggcttt gctgcggatt gtctggagac
    17761 gctggaagag attgccgagc aaaaccgtga ggtcttcctc ggtgccggcg ggaaaaaata
    17821 tgaatatatt ccggcgctta atgccacgcc ggaacatatc gaaatgatgg ctaatcttgt
    17881 tgccgcgtat cgctaaagct gagcggtaaa gaactgagcg ccgtcgcgaa gagcctcgtc
    17941 ggcggttttc atcatccgtg aataatgcaa aaaggcgtgc agcgtgcctg ggtagagttt
    18001 gaactcacag ggctgctgat gcgccgctaa cgtctggtaa agcagacggc tgtcatccag
    18061 cagcggatcg aactccgccc cggcaataaa acagggcgga acttcgcgag tgagatcatt
    18121 attaaacaga cagtaatacg gcgactcgcg gtccgcgtcg ttgcttaaat atgcctcttc
    18181 gtacatctgc aaatcctgtt gcgttaagcc atcccagaca ctgcccaaca gacgacgagt
    18241 cacggaatcc cgtaatccgt aaagcccata ccacagcaaa acgcccgcaa ctttaccgca
    18301 atcgatctgt ttatcacgca accacaacgc actggcgagc gccagcatgg cacctgcgga
    18361 atcaccggca aagccaatgc gggacatatt gatttgataa tcctccgcct gctggtggaa
    18421 ataacaacaa gcagccacaa tttcctctat cgcttgcgga aaacgcgctt caggtgaaag
    18481 ggtgtaatca ataccaatca ccgtacattg gctgtagctt gccagcaggc gcatgatgcg
    18541 atcgtgggta tcgagattgc cgagaataaa accgcctcca tgcaaataaa atagcgtcgc
    18601 tgggctatct ggctgcggac aaaagagacg tgtttccacc tgcccatatt ttgttggaac
    18661 catgtaagct ctggttgcca tttctggagc gcccgcattc cagaatcggc gctcaagcgt
    18721 gtaatactgt cgttgctcag caatcgttcc cgttgcgggc cagggcggta aatccggctg
    18781 aagagtattc acaacggtct tcatttcagc agaaataagg tccagaacag gtagtttgtt
    18841 ttccggcttc atacaaaaac tcctttcaaa ttacgtcatt gtaaggaacc actgccatga
    18901 aaatgcgatc ccgcctgctg atattgaaac tggctgcgtc tcgcgcgctc ccgtcagatt
    18961 gtgttaacat tcgccgctca gttaaccacc cgtaaaaaca accatgaaat ttcccggtaa
    19021 acgtaaatcc aaacattact tccccgtaaa cgcacgcgat ccgctgcttc agcaattcca
    19081 gccagaaaac gaaaccagcg ctgcctgggt agtgggtatc gatcaaacgc tggtcgatat
    19141 tgaagcgaaa gtggatgatg aatttattga gcgttatgga ttaagcgccg ggcattcact
    19201 ggtgattgag gatgatgtag ccgaagcgct ttatcaggaa ctaaaacaga aaaacctgat
    19261 tacccatcag tttgcgggtg gcaccattgg taacaccatg cacaactact cggtgctcgc
    19321 ggacgaccgt tcggtgctgc tgggcgtcat gtgcagcaat attgaaattg gcagttatgc
    19381 ctatcgttac ctgtgtaaca cttccagccg taccgatctt aactatctac aaggcgtgga
    19441 tggcccgatt ggtcgttgct ttacgctgat tggcgagtcc ggggaacgta cctttgctat
    19501 cagtccaggc cacatgaacc agctgcgggc tgaaagcatt ccggaagatg tgattgccgg
    19561 agcctcggca ctggttctca cctcatatct ggtgcgttgc aagccgggtg aacccatgcc
    19621 ggaagcaacc atgaaagcca ttgagtacgc gaagaaatat aacgtaccgg tggtgctgac
    19681 gctgggcacc aagtttgtca ttgccgagaa tccgcagtgg tggcagcaat tcctcaaaga
    19741 tcacgtctct atccttgcga tgaacgaaga tgaagccgaa gcgttgaccg gagaaagcga
    19801 tccgttgttg gcatctgaca aggcgctgga ctgggtagat ctggtgctgt gcaccgccgg
    19861 gccaatcggc ttgtatatgg cgggctttac cgaagacgaa gcgaaacgta aaacccagca
    19921 tccgctgctg ccgggcgcta tagcggaatt caaccagtat gagtttagcc gcgccatgcg
    19981 ccacaaggat tgccagaatc cgctgcgtgt atattcgcac attgcgccgt acatgggcgg
    20041 gccggaaaaa atcatgaaca ctaatggagc gggggatggc gcattggcag cgttgctgca
    20101 tgacattacc gccaacagct accatcgtag caacgtacca aactccagca aacataaatt
    20161 cacctggtta acttattcat cgttagcgca ggtgtgtaaa tatgctaacc gtgtgagcta
    20221 tcaggtactg aaccagcatt cacctcgttt aacgcgcggc ttgccggagc gtgaagacag
    20281 cctggaagag tcttactggg atcgttaagt tatcgtcggt tcgtaggcca gataaggcgt
    20341 tcacgccgca tctggcattt ggctctcgat gcctgatgcg acgctggcgc gtcttatcat
    20401 gcctacatat ttttcatatt ttacatccgg caaccaccgt ttaccccgtc accacctcac
    20461 ccgccggtgg cgtttccagc agttccagca tggtacgggc gatttcacgc tcgcccatca
    20521 ctacctgatt cgcaccacgt tcggtgatat acgccacttc atcgtcataa tgggcgcggg
    20581 caataatctc aatatccgga tttttcgcgc gggcagatgc cacaatctca cccgcttcat
    20641 aaccgttggg aatcgtcagg atcagccatt ttgcacattc cagatgcgcc agttgcataa
    20701 tttcttcgtt cgccgcattg cccaatactg cgcggacccc gcgctctcgc agctcatcaa
    20761 cacgggttcg tgacgtctca atcaccacca gcggaatatc agaggcgagc aatttctccc
    20821 ccagcaggct gcctacacga ccgtaaccca ccagtagcgc atggttgcaa atatccactg
    20881 ggatctgctt ctcttcttcg attgcctctt ccagcgtctg ctcttccagc gtttcggtct
    20941 tcgccagata tttctccagt agtgcgaaca gtaccgggtt gagcataatc gacaggatcg
    21001 cccctgccag taccaggttt tgtccggcct gcggcagtaa attcaatgcc attcccagtc
    21061 ccgccaggat aaacgcgaac tcaccaatct gcgccaggct ggcggcgatg gttaatgccg
    21121 tacgttggga gtgaccaaac agtcgcacca ggaaaaatgc ggctaacgac ttaccaaaca
    21181 gaataatcgc cagcgtcgcc agcactgcca gcggttgctg aatcagaatt aacggatcaa
    21241 acaacatccc gacggagaca aaaaacagca ccgcaaacgc gtcgcgcaat ggcagcgtat
    21301 cgtgggcggc acggtgactc agttcagact cgttcagtac catcccggca aagaacgcac
    21361 cgagtgcaaa ggagacatca aacagctcta ccgcaccaaa ggcaacccct aacgccagcg
    21421 ccagcaccga cagggtaaac agctcgcgag aaccggttgc cgcgctgcgt gccataatcc
    21481 acggcaccag acggcgacct accagcatca taatggcgat aaatgcgatc actttgccga
    21541 tggtgatccc catatcgact gcaagagtgg caaagcccac atcgccctgt tccatcattc
    21601 ctgccactgc gggcagcaac accagcgtca gaaccattac caggtcttcc acaatcaacc
    21661 aaccgatggc gatttgccca cgctgactgt caattaattg ccgttcttca agtgcgcgca
    21721 gtaacaccac ggtactggcg gtggaaagac ataaaccgaa cacgataccg gtcattaacg
    21781 accagcccag cacggcagag agcgccatac ccagcagcgt cgccacggct atctgggcga
    21841 tcgcaccggg aatggcgatg gcctttaccg ccatcaaatc cttcagcgaa aagtgcaaac
    21901 cgacgccaaa catcaacaga atgacgccca gttcagccag ttccggggca agcttggtat
    21961 cggcaacaaa gcccggagtg aatggtcctg ccagcacacc cgctaacaga tatcccacca
    22021 gaggagaaat acgtagttta ttggccagca tgccgaggat aaaggcgagc acaaggccgc
    22081 caacaatggt ggtgataagc ggggtggcgt gatgcattcc gtctcctttt cctggtggtt
    22141 attgtccatt tttggccggg aaaaccaaaa ttacaggtaa tagtttatga caatttcatt
    22201 gatgatgttc atgaataatt attgaatttt gcagaaaaat ggaattagct gcaaaaaaag
    22261 cacggatcgg aaaacagaag gcggtttaac agaggaaagg cttatggcga ctgtaaaacg
    22321 atgcagccaa agtttgcctt tggctgcaat gaaatcagtc tttatgccgg ttatcaggca
    22381 ggaatatggt caacatcccc aatagtggca ggaaagcaca gattttatag actaactcga
    22441 tgctggtgtg atcggcgata agccccagaa ctgccgctcc cagacctccc atgccaaaag
    22501 caaaaccgaa aaagagtcca gaaaccatac cgatacgtcc tggaagcagc tcctgagcgt
    22561 agaccagaat ggcagagaat gccgaagcga ggataaatcc aataatcacc gttaaaaccc
    22621 ccgtccagtg caggctggcg tagggtaaaa tcagcgtaaa cggcgcaacg ccgaggatag
    22681 agccccaaat cacatatttc cgcccaattt tatcccctac aggcccgccg atcaccgtac
    22741 ctgccgcaac ggcaaacagg aaggcaaaca gatgaagctg agcattctgg atagataatc
    22801 cgaatttttg catcagataa aaggtgtaat agctgctgat gctcgccata tagaaatatt
    22861 tcgagaaaat gaggattaac agaatgctga ccgccagtac aactttattg cgcggcagtg
    22921 gattgataat cgtcgctttg ggttttcctt tattcattcg gtgctgtgcc gagtaccaac
    22981 ggctgatttg cgccaacacc acgatcgcca gcagtgccgc aagcacaaac caggcaacgt
    23041 tgcctttgcc ataaggcgcg ataatcaccg ccgccagcaa gggtcccagg gaactgccaa
    23101 agttgccgcc gacctgaaag atagattgcg ccaggccatg ccgcccgccg gaagccatac
    23161 gggccacgcg agaagattcc ggatgaaaga ccgatgaacc ggtaccgacc agcgccgccg
    23221 ccagcagaac tgcgccaaaa ctgcccgcca gcgcaagcag caccagaccg cttaaggtaa
    23281 agcacatgcc aattggcaac gaccatggca tcggatattt atcggtccag tagccgacca
    23341 ctggttgcag tagcgaagag gcgagctgga aggtgagggt tatcatgcca atctgcataa
    23401 atgtcagaga aaattctgac tgaagcagcg gataaatcgc cagaatcagc gattggatca
    23461 tgtcgttcag cagatgtgag aggctgatag cacctaaaat accaaacgat gttcgggcct
    23521 tggtcgttga cgcagccgcg cccgccacag gctggggttg ttcactcatt gccataggaa
    23581 agtcactttt tcagggttgc gatgtaaaga atgatcttat ttgtgattat taccagacta
    23641 acatacctgt atgcgtcgtc tgaaggaagt ctcaacgccg aatacagaat ttctaatctg
    23701 gatgcagatt tatcttcacc ggacgcagac ttgtctatga tgtcgcgtca tactattttt
    23761 caacacgttg aaatcaggtc agggagagaa gtatgaaatt attgcagcgg ggcgtggcgt
    23821 tagcgctgtt aaccacattt acactggcga gtgaaactgc tctggcgtat gagcaggata
    23881 aaacctacaa aattacagtt ctgcatacca atgatcatca tgggcatttt tggcgcaatg
    23941 aatatggcga atatggtctg gcggcgcaaa aaacgctggt ggatggtatc cgcaaagagg
    24001 ttgcggctga aggcggtagc gtgctgctac tttccggtgg cgacattaac actggcgtgc
    24061 ccgagtctga cttacaggat gccgaacctg attttcgcgg tatgaatctg gtgggctatg
    24121 acgcgatggc gatcggtaat catgaatttg ataatccgct caccgtatta cgccagcagg
    24181 aaaagtgggc caagttcccg ttgctttccg cgaatatcta ccagaaaagt actggcgagc
    24241 gcctgtttaa accgtgggcg ctgtttaagc gtcaggatct gaaaattgcc gttattgggc
    24301 tgacaaccga tgacacagca aaaattggta acccggaata cttcactgat atcgaatttc
    24361 gtaagcccgc cgatgaagcg aagctggtga ttcaggagct gcaacagaca gaaaagccag
    24421 acattattat cgcggcgacc catatggggc attacgataa tggtgagcac ggctctaacg
    24481 caccgggcga tgtggagatg gcacgcgcgc tgcctgccgg atcgctggcg atgatcgtcg
    24541 gtggtcactc gcaagatccg gtctgcatgg cggcagaaaa caaaaaacag gtcgattacg
    24601 tgccgggtac gccatgcaaa ccagatcaac aaaacggcat ctggattgtg caggcgcatg
    24661 agtggggcaa atacgtggga cgggctgatt ttgagtttcg taatggcgaa atgaaaatgg
    24721 ttaactacca gctgattccg gtgaacctga agaagaaagt gacctgggaa gacgggaaaa
    24781 gcgagcgcgt gctttacact cctgaaatcg ctgaaaacca gcaaatgatc tcgctgttat
    24841 caccgttcca gaacaaaggc aaagcgcagc tggaagtgaa aataggcgaa accaatggtc
    24901 gtctggaagg cgatcgtgac aaagtgcgtt ttgtacagac caatatgggg cggttgattc
    24961 tggcagccca aatggatcgc actggtgccg actttgcggt gatgagcgga ggcggaattc
    25021 gtgattctat cgaagcaggc gatatcagct ataaaaacgt gctgaaagtg cagccattcg
    25081 gcaatgtggt ggtgtatgcc gacatgaccg gtaaagaggt gattgattac ctgaccgccg
    25141 tcgcgcagat gaagccagat tcaggtgcct acccgcaatt tgccaacgtt agctttgtgg
    25201 cgaaagacgg caaactgaac gaccttaaaa tcaaaggcga accggtcgat ccggcgaaaa
    25261 cttaccgtat ggcgacatta aacttcaatg ccaccggcgg tgatggatat ccgcgccttg
    25321 ataacaaacc gggctatgtg aataccggct ttattgatgc cgaagtgctg aaagcgtata
    25381 tccagaaaag ctcgccgctg gatgtgagtg tttatgaacc gaaaggtgag gtgagctggc
    25441 agtaatccga aagtgccgga tgtttgcatc cggcacaatg cttaatcgcg gcgggcgata
    25501 tcagcaaatt tggcatcgag gatctttgcc agatcgcctg ccgccagttc gatatccagt
    25561 ccgcgcttgc cgccggaaac ataaatagtg gcaaattctt gtgcgggggc gtcgataatc
    25621 gttggcagac gttttttctg ccccagtggg ctaatccccc caaccaggta tcccgtcgaa
    25681 cgctgcgcga ccatcggatc ggccatctca actttcttgg cacccagcgc ttttgctact
    25741 tttttaagat ccagttgacc tgcgaccggc gtaacggcca cggcaaggtg tttcatatca
    25801 ccgttcactg ccaccagcag cgttttgtag acctgatccg gattcaaacc taattttttg
    25861 acgacttcat cgccaaaatt ggtttcagcc ggatcgtgct cgtaggtatg gatttgaaac
    25921 gaaatcttgt ttttttcgag taatttaact gcgggtgtca tggtaatttt cctgccttaa
    25981 acaaaaaaac gaagcaagca tacgcctgat ggcggtccaa aaaaaagagt catcttgcct
    26041 aagagtattg gcaggatggt gagattgagc gacaatcgag ttacaccgtc gcttaaagtg
    26101 acggcataat aataaaaaaa tgaaattcct ctttgacggg ccaatagcga tattggccat
    26161 ttttttagcg caacatttgc ggcaaattcc cttctccata caggtgtagt gcaccgaccg
    26221 cgaccacata tcgccccggc ggcatggcgc gtaatttatc ccgccaggcg agatttcgct
    26281 gatgcatcag cacatcgtac agcgactgac tgaacgtatt gggcagcgtt atatcattat
    26341 tttgcggcgg tgcattcagc caccagctca tcatttgttg cagcaaccgt gcgttggtat
    26401 gccagtgggt cagcgtatcg tccagcagcg ccagtccttt gtcagggagc tggagcaaca
    26461 tggcaatctg gttttcagcc ccttccagtt caatcacggg tttatgttgt tgcttcgccg
    26521 cctgcaatag ctggtaatcg ataccgtatt ctgcccgcag ccccagtttt tgtgcctgcg
    26581 tcgcctgaag aaccatcgcg atttgccaca gcggttgggt agaaaagagt gagggagaaa
    26641 tgcctatctc ctggctaatg tgctgcaggt tttggagttg ctcctcgcta atgcgctctt
    26701 ccagcgcctc gcaggcaggc aaattagcaa aaggcgtatc gctggtggaa acatccgcct
    26761 cgacgatcag cgcatcggcg tttttgagct ttttgagcaa acgggtgggc aggggagcca
    26821 tatcgtggct acccatatga atactgccaa tcagatgaaa atggcgattg ccggggaggg
    26881 tgatatcgat ggcaggccag gtgtaatgat taccgcgcag cgcggcccaa agcgttttta
    26941 cccggtacaa cagatccata cgacctccct ttgtgaaata tcatgctagc gcgcggtgag
    27001 ggatggcgca aatggagttg gagacttgtt taatgtgttt gtatgattca gtatgttctt
    27061 gcatcgctat tcacaaggaa gcaacagtta aaaaccatga aacaggcaac aagaaaaccg
    27121 acgacacccg gagatattct tctctatgaa tatctggaac cgctcgattt gaaaatcaat
    27181 gagttagcag agttgctgca tgttcatcgt aatagcgtca gtgcactgat caataacaat
    27241 cgtaaactca ctactgagat ggcatttcgt ctggcgaaag tttttgatac cacagtcgat
    27301 ttttggctaa acctccaggc ggcggttgat ctttgggaag ttgaaaacaa catgcgcacc
    27361 caggaagaat tgggacggat tgaaacagtg gctgaatatt tggcacgccg tgaagagcgt
    27421 gcaaaaaagg tcgcgtaagg ccaaaacatc gcttcatctc gtaggccgga taaggcgttc
    27481 acgccgcatc cggcatccga gcaccattgc ctgatgcgac gcttacccgt cttatcaggc
    27541 ctacaaactt gtgcctgaac cgtaggccgg ataaggcgtt tacgccgcat ccggcatccg
    27601 agcaccattg cctgatgcga cgcttacgcg tcttatcagg cctacaaacc tgtgcctgaa
    27661 ccgtaggccg gataaggcgt ttacgccgca tccggcagtc atgcgtcgat gccaaatgcg
    27721 ccaccctaaa gcagcgcatc cgcaatgatg tacttattcc ttcggtttaa accgcagcaa
    27781 ccggttggcg ttactcacta cggtaatcga cgagagcgcc attgccgctc cggcaactac
    27841 cgggttaagc agtgttccag tgaacggcca caaaataccg gcggcgaccg gaataccgat
    27901 actgttgtag ataaacgcac cgagcaggtt ctgcttcatg ttgtgcagcg ttgcgcggga
    27961 aatagcgagc gcatccgcaa cgcccatcag gctatggcgc atcagggtaa tcgccgcggt
    28021 ttcaatggca acatcactgc cgccacccat cgcaatgccg acatccgcct gagccagcgc
    28081 tggcgcgtcg ttaatgccgt cgcccaccat tgccacctga cgtccttcac tttgcagatg
    28141 tttgatcgct tcggctttac cgtccggcag caccccggcg atcacctcat caatccctgc
    28201 ttctttggcg atcgcattgg cggtggttgg gttatccccg gtcaacatca ccagacgata
    28261 tcccgcttta tgcaggcgtt gcagcgccgc cacgctatca ctacgcaacg gatcgcgtac
    28321 tgccagcagg gctaccgctt tcccgtcaac cgccagcagc acaggcgttg ccccttgcga
    28381 tgcctgagca gtaatctccg cttcgatagc tttggtacca acctgttgct catttaacag
    28441 cgcctgattg cccagcaata acgcatgacc ttcagcttca ccgctcacgc ccagcccgcg
    28501 caatgtgcgg aaaccgttga cctgcggtag ctgcatatca cctgctttat cgaggatcgc
    28561 tcgtgccagc ggatggctgg aaccttgctc cagtgccgcc gccagacgca atgcctgcgc
    28621 ttcatcaaca tcagcaaatg ttttcactgc gacaacctgc ggcttccctt cagtcagcgt
    28681 cccggtttta tcgaacacta cagtgtcgag tgtactggcg cgttgcagcg cgtcagcgtc
    28741 ccgcaccagc acgccaaact cagccgcccg cccgacgccg gaaataatcg acatcggcgt
    28801 cgccagcccc agcgcacacg gacaggcaat aatcagtacc gtggtggcaa tcaccagggt
    28861 atagacaatc tgcggtgccg gaccaaagaa ataccagatt gccgcactga caagcgcaat
    28921 aaccaccact accggcacaa atacggctga gattttatcc gccagctgac cgatttctgg
    28981 cttgctgctc tgggcctggc gcaccatgcg aatgattcgt gacagcgtag tatggctgcc
    29041 aaccgcactg gcacgaaaca gcacactgcc gtcctgtacc actgtcccgg catggacgct
    29101 atcgccttcg cctttttgct gcgggattgg ttcgcccgtc agcatcgctt catccagcca
    29161 tgcttcgccc tgggtaatct cgccatctac cggcacgcga tcgccggtcg tcaggcgcag
    29221 caacatacct ggctgcactt ctgccagagg cacgcttttt tcaccttcgt cagtaaccag
    29281 gcgtgccgtc ggcggggtta aatcgagtaa cttttccagc gccttagaag aacgctggcg
    29341 tgcgcgcgct tccagcatat ggccgagatt gatcagaccg ataatcatcg cgctggcttc
    29401 gtaataaaga tgtcgcgctt ccatcgggaa ccactgcggc cacaggttga cgctcatcga
    29461 atagagccac gccacgccag tacccagcgc caccagcgta tccatcgtcg ccgcaccgtt
    29521 cagcaggctt ttccatgcac tgcggtaaaa atggccgccg gcgaaaacca tcactgccag
    29581 ggttatcagg ccgataacca accacaggct gcggttgtca gcggtgacca tcatgttatc
    29641 gccgatcatc ccccagacca tcaccgggat acccaccgcc agtgcgacaa ttgcctgcca
    29701 gcggaagcgc ttcatcgtag cgacggcggt ttcttgctgg cgctcgcggc gtttagcgtc
    29761 atcttcaatc gcttccgcgc cgtagcccgc tttttccacc gcctgcacta aatcttgtgg
    29821 ggaggcactg cccatcacca gcgcagtacg ctccgccagg tttacccgtg cctgagtgac
    29881 gcccggtacg ctttgcagcg cattttgtac gcgggtgaca cagctggcgc agctcatgcc
    29941 gctcagcagc aactgctggc tgtcatcgtc atcggcggtc gctgccggaa gcgcctcaga
    30001 aaccgctgtc agtgcttccg acgggattga tgactccgcc agcggtttag cctttgggtg
    30061 gcttacagat gcgtcataac ccgcttgttt gatggtttcg atcagctgtt ctgcactggc
    30121 agtcccggta acgtgcgctt cagtgataga cacatccgcc tgctcaacat ccggacgctg
    30181 ttcaagactt tctttcacgc gtttaacgca gtgaccgcag gacaggccgt ccagggtcag
    30241 gtcgatagtt tgtgacataa aacactcctt taagacagtt ttgactggct gtgataaagg
    30301 ttaaaccttc cagcaagggg aaggtcaaga aattaataaa ccaggcgggt aaaagtccgt
    30361 aaagattaaa aaatcggctc gatttgcatc aggattagac atttatctct ttgttttcct
    30421 gtagttaagt tgcgggtgct aagttaaatc aggatgcctg aaaatcggca ccggggtgag
    30481 gaattacctc ccgcatctat aaaaaggagt taacaaaaga tgttagatgc aaacaaatta
    30541 cagcaggcag tggatcaggc ttacacccaa tttcactcac ttaacggcgg acaaaatgcc
    30601 gattacattc cctttctggc gaatgtacca ggtcaactgg cggcagtggc tatcgtgacc
    30661 tgcgatggca acgtctatag tgcgggtgac agtgattacc gctttgcact ggaatccatc
    30721 tcgaaagtct gtacgttagc ccttgcgtta gaagatgtcg gcccgcaggc ggtacaggac
    30781 aaaattggcg ctgacccgac cggattgccc tttaactcag ttatcgcctt agagttgcat
    30841 ggcggcaaac cgctttcgcc actggtaaat gctggcgcta ttgccaccac cagcctgatt
    30901 aacgctgaaa atgttgaaca acgctggcag cgaattttac atatccaaca gcaactggct
    30961 ggcgagcagg tagcgctctc tgacgaagtc aaccagtcgg aacaaacaac caacttccat
    31021 aaccgggcca tagcctggct gctgtactcc gccggatatc tctattgtga tgcaatggaa
    31081 gcctgtgacg tgtatacccg tcagtgctcc acgctcctca atactattga actggcaacg
    31141 cttggcgcga cgctggcggc aggtggtgtg aatccgttga cgcataaacg cgttcttcag
    31201 gccgacaacg tgccgtacat tctggccgaa atgatgatgg aagggctgta tggtcgctcc
    31261 ggtgactggg cgtatcgtgt tggtttaccg ggcaaaagcg gtgtaggtgg cggtattctg
    31321 gcggtcgtcc ctggagtgat gggaattgcc gcgttctcac caccgctgga cgaagatggc
    31381 aacagtgttc gcggtcaaaa aatggtggca tcggtcgcta agcaactcgg ctataacgtg
    31441 tttaagggct gatcatgatg aacacggaag gtaataacgg taacaaacct ctcggtctat
    31501 ggaacgtcgt ttccatcggc attggggcaa tggtgggggc ggggatcttc gcgctgctgg
    31561 ggcaggctgc attgctaatg gaagcctcga cctgggtcgc ctttgctttt ggcggtattg
    31621 tggcgatgtt ttccggttat gcctatgcgc gtctgggggc gagctatccc agcaatggcg
    31681 gcattatcga cttctttcgt cgcggattag gcaacggcgt cttttcgctg gcgctctcgt
    31741 tactgtacct gttgacgctg gcggtgagca tcgccatggt cgcccgtgct tttggcgctt
    31801 atgccgtgca gtttttgcat gaaggcagcc aggaggagca ccttattttg ctctacgcgt
    31861 tggggatcat tgcggtgatg acgcttttca actccttaag caaccatgcg gtagggcggc
    31921 tggaagtgat cctcgtcggc attaaaatga tgatcctgtt attgctgatt attgccggtg
    31981 tctggtcgct gcaaccggcg catatttccg tctctgcgcc ccccagctcc ggtgcgttct
    32041 tctcctgtat tgggataact ttccttgcct atgcgggctt tggcatgatg gcgaacgcgg
    32101 cggataaagt gaaagatccg caggtcatta tgccacgggc gtttctggtg gcgattggcg
    32161 ttaccacgtt gctttatatc tcgctggcac tggttttgct tagcgatgta tcggcattag
    32221 agttagaaaa atatgccgat accgccgtag cgcaggctgc ttctccgctg ctcgggcatg
    32281 tgggttatgt gatcgtcgtc atcggcgctt tactggcgac ggcttcagcc attaacgcga
    32341 acctgttcgc cgtgtttaac atcatggaca acatgggcag cgaacgcgaa ctgccgaagc
    32401 taatgaataa atccctgtgg cggcagagta cctggggcaa cattattgtc gtggtgttga
    32461 ttatgctgat gacggcggca ctgaatttag gctcactcgc cagcgttgcc agcgccacct
    32521 ttttgatttg ctacctggcg gtgtttgtgg tggcgatccg cctgcgtcat gatattcacg
    32581 cctcgttgcc gattcttatc gttggtacgt tggtgatgtt gttggtgatc gttggcttta
    32641 tctacagtct gtggtcccag ggtagccgtg cgttgatatg gattattggc tcactcttac
    32701 tcagccttat tgtggcaatg gtcatgaagc gcaataaaac cgtataacat ctctctgtgc
    32761 gcagtacttc ctgtattatt gtggtggcgg tcgatattcg cactggcaaa aaaacgtgct
    32821 tgaatatctg ttgaaaccct ttaacaaagc acaggaggcg ttgcgcgaac gatgaacatc
    32881 agcgatgtag caaaaattac cggcctgacc agcaaagcca ttcgcttcta tgaagagaag
    32941 gggctggtga cgccgccgat gcgcagcgaa aacggttatc gcacctacac gcagcagcat
    33001 ctcaacgaac tgaccttact gcgccaggca cggcaggtgg gctttaacct ggaagagagc
    33061 ggcgagctgg tgaatctgtt taacgacccg cagcggcaca gcgccgacgt caaacggcgc
    33121 acgctggaga aggtggcgga gatcgaacga cacattgagg agctgcaatc catgcgcgac
    33181 cagctgctgg cactggcgaa tgcctgccct ggcgatgaca gcgccgactg cccgattatc
    33241 gaaaatctct ccggctgctg tcatcatcgg gcagggtgat taagacgaga cggctcggat
    33301 atgtagggtt atcccttcta tcgcaatgac ttcaacatgc gtacctgcac cgagatcctc
    33361 gctggcgctg acaggccatg aactgtcacc gacgcgcata tgaccgcgcc cgttgaccag
    33421 cggagattcc agcacaaaac gtcggccaat cagctgctgc ccgcgctggt ttaaatgact
    33481 atcgctgtgc ttttgttcgc gcacccgccg cgacaaccat ttccaccaca gccaggcggc
    33541 gagcagcgtc aggatggcaa acattacccc ttgccactcc caacccagcg gcaccagcca
    33601 gaccaccagg ccggtaatca ccgctgccac gccgctccac aacaaataac catttccgcc
    33661 cagcatctcg gctgccagca gcaaaccgcc gagactgagc cagaaaatat gtggatgaac
    33721 gaccattaac tccatcatgg ctgagtccgt ttgttggcgc tgtctttcac cagctcggca
    33781 atcccggcaa tcgaccccat caggctgctg gcctctaatg gcatcatcac tactttgctg
    33841 ttactggagg aaccgatctg ctgtaacgct tcggtgtatt tctgcgctac gaagtagttc
    33901 accgcctgaa tatcaccgga ggcgatagct tcagacacca ttttggtggc gcgggcttct
    33961 gcttcggcgg aacgttcacg cgcttcagcc tgtaaaaacg ccgactgacg ttcgccttcc
    34021 gctttcagga tttgcgactg tttttcacct tcggctttga ggatttccgc ctgacggatc
    34081 ccttccgctt caagaatgta agcgcgtttg gtacgttccg ctttcatctg cgcgttcatt
    34141 gaagagataa gctctgccgg tgggcgcacg tcgcgaattt caatacgggt gactttaatc
    34201 ccccacgggt tggtggcttc atcgacaata cgcagcaggc gtgagttgat gctgtcgcgc
    34261 tgagagagca tttcgtcaag ttccattgaa cccagcacgg tacggatgtt agtcatggtc
    34321 aggttgatga tcgccagctc cagattgctg acttcataag ccgcgcgcgg cgcgtcaatc
    34381 acctgaataa agcacacggc gtcgatggta acgttggcgt tatctttcga gataacttcc
    34441 tgggaaggga tatcgagcac ttgctccatc atattgatct tgcgaccaat gcgatccata
    34501 aacggcacca ccagactgag ccccggctgt aacgttttgg tatagcgacc aaagcgttct
    34561 actgtccact gatagccctg cggtacgatt ttgacacccg cgccgacaat gaccagcgcg
    34621 acaaaaatga gaatcgggat aaagataagc atcggaaaaa cctcctgttg taccgtccat
    34681 aatcagcaaa attgctgctt gattaaacaa attatacctg attactgaaa gagagttccc
    34741 ccttattcct gcgaaggata aactgttttt agtaaaaatc agaaaaaggg aacagcgatg
    34801 caggaaaata gtcctttgct tcagctacaa aacgtaggat atctggcggg tgatgcgaag
    34861 attcttaata acatcaattt ttcgctgcgt gctggcgaat ttaagttaat taccggtcct
    34921 tctggttgtg gcaaaagtac gctgctaaaa atagttgctt cattgatcag cccaaccagc
    34981 ggaacgttac tgtttgaagg tgaggatgtc agcacactaa agccagaaat ctaccgccaa
    35041 caagtctctt actgcgccca gacaccgacg ctgtttggcg atacggtata cgataatctg
    35101 atctttccct ggcagatccg taaccggcag cctgacccag ccatttttct cgattttctc
    35161 gaacgcttcg ccttgccgga cagcattttg acgaagaata tcgccgagct atctggtggt
    35221 gaaaaacaac gcatctcatt gattcgtaac ctgcaattta tgccgaaggt tttattgctg
    35281 gatgaaataa ccagtgcgct ggatgaaagt aataaacata acgtcaatga gatgatccat
    35341 cgttatgtgc gcgagcaaaa tattgccgtg ctgtgggtga cacacgataa agacgaaatt
    35401 aatcatgcgg ataaagtgat tacactgcaa ccgcatgccg gagaaatgca ggaagcacgc
    35461 tatgaactcg cataatatta ctaacgaatc attagcactg gcattaatgc tggtggtggt
    35521 ggcaatctta attagccata aagaaaaact ggcgctggag aaagatattc tctggagcgt
    35581 cgggcgagcg ataattcagc tgattattgt cggctatgtg ctgaagtata ttttcagcgt
    35641 ggatgatgcc agcctgacat tattgatggt gttatttatc tgctttaatg cggcgtggaa
    35701 cgcgcaaaaa cgcagtaaat atattgctaa agcttttatc tcatcgttta ttgccattac
    35761 ggtcggggcg ggaattaccc tggcggtgct gattctctca gggtcgattg aatttatccc
    35821 gatgcaggtg atccctatcg ccgggatgat tgccggtaac gccatggtag cggtggggtt
    35881 gtgttacaac aatttagggc aacgggtcat tagcgaacag caacagattc aggagaaact
    35941 gagtcttggt gcgacgccga agcaggcttc agcgatattg attcgcgaca gtattcgcgc
    36001 ggctttaatt ccgacggtcg attcagcaaa aacggttggc ttagtgagtt taccaggaat
    36061 gatgtccggg ctgatatttg ccgggattga tccggtgaag gcgattaaat atcagattat
    36121 ggtgaccttt atgctgctct caaccgccag cttgtcgacc attattgcct gctatttaac
    36181 ctatcgtaag ttttataatt cgcgccacca gttggtggtg acgcaattga agaagaaatg
    36241 atgcgatgcc ggatgcgcag catcgcatcc ggcgttgtgg ttcatgtgcc gatcaacgga
    36301 atatcaatac aacaatgcat acagctggcg gcgatacttc gacgccagtg catcacccgt
    36361 acccagcgca gcgaggatct cctggaacgt tttacgcgtc tgaccgtctg cggcggtgag
    36421 atctttacgc agatgcccga acagcaactc cagcgcctct tcattgcgcc caacctgatg
    36481 cagttgcagc gccagttgcg tcgccagtgc ggcatcttct ggattctccg ccacctgctg
    36541 ttgcaactgt tgaatttccg gcgtatcagc cgcctgcttc agcagttcga tttgcgccac
    36601 cagcccctgg tagcgggtgt cctgatcctg caacggaatg gttttcagca ccgcttccgc
    36661 atcttcagaa cggttcagcg caatcagcgt ttctgccagc agcaggccga tctccccgtt
    36721 ctgattcgac aactgccagg cgtctttcag caatggcagg gcatcggtgt aattgctttc
    36781 ctgcatcagt tgcatcgcct gctgcgcttt cagctcttct tcgcgcggca gcactttatc
    36841 cagcagggcg cggatcgcct cttccggttg cggcccctgg aagccatcta ccggttgccc
    36901 gttctggaac agatacacgg tcggaatcgc acgcagacca aactgcgcgg caatcatctg
    36961 ctccgcgtcg cagtccagct tcgccagaat aaattgcccg ttgtactgcg ccgcgaggct
    37021 ttccagaatt ggggttaact gcaaacagtg ctggctacgt tcagaccaaa aatagaacag
    37081 caccggagtg gtcatcgact gttcaagaac ctgttgcagg ttagattcgt taatgttgac
    37141 aatattttct acggacatgg agtcgctctc tgttgtcgat attttctttg acatgggggc
    37201 ttaagcgcgc gcttcaactc acccctgcaa tattttgtcc atcacgcgcc ccggcagcag
    37261 gcgcttaagc accattaccg cccaggtcac cagcgtcacc ggatagcgca tcttcggctt
    37321 ctcgctaata aaagcatggc gtactttgtc caccaccgct tccggtccca acgtaaagcg
    37381 ggcggcgatg ctgggatttt cgactggttt atcactttgc gtctggttga cgttgtcggt
    37441 gaagcgagta cgaatgggac cgggttcgat caggctgact ttaattccgc tgtggcgcag
    37501 ctccatgcgc agtgcgtctg accacgcctc cagcgcatat ttactggccg cgtaagcgcc
    37561 acgacccggc gtggagatta atcccatcac cgatgatgtc atcacaatac gcccttcacc
    37621 gtgcggtaac atcgcgggta acaggcgcat ggtgagctgg tgtgcgccga aaaagttggc
    37681 ggaaaactgc tgttccatct gcgcacggct gatggtggaa agggggccat acatgccgaa
    37741 tccggcattg ttaaagatcc catacagaca attatcggtc agggcgatca cctcgtcggc
    37801 tgcgcgatca acactttctg gtgaatccag atcgatcaac acgccggtaa atcccatgct
    37861 gttcatgcgc tcaacatcat ccggtttccg gcaacctgcc agcacatgaa aaccctggcg
    37921 ttttaattcg agcgcgcttt ccaggccaat tccactggaa catccggtaa ttaagaccga
    37981 tttttgcata actttacctg tcaggatctc cgttgcttta tgagtcatga tttactaaag
    38041 gctgcaactg cttcgccatc cagtcggcaa taaacggctg ggcgtcgcgg ttgggatgaa
    38101 taccgtcatc ctgcatccat tgtggcttga ggtagacctc ttccataaaa aagggcagca
    38161 gcggaacatc aaactctttg gcgagtttgg ggtaaatggc gctaaaggct tcattataac
    38221 ggcgaccata gtttgcaggc agacgtattt gcattaacaa tggttcagcg ttggcggctt
    38281 tgacatcctg caaaatctgg cgcagcgttt gctcggtttg ctgtggctga aaaccacgca
    38341 aaccgtcatt gccgcccagt tcaaccagca cccaacgcgg ctgatgctgt ttcagcagag
    38401 ccggaaggcg cgccagtcct tgttgcgagg tgtcgccgct gatgctggca ttaactaccg
    38461 acgttttact ctgccactta tcattcaaca aggcaggcca ggccgcgctg gcagacattc
    38521 gatacccggc gctcaggcta tcacccagaa tcaataacgt gtccgctgcg gcggcacgga
    38581 aggttaacag gaccaggaac aggaagggca aatgccagcg gaaaacattg ttgaagttca
    38641 tcatcttaag aagtccgtcg gtcaggggga gcatgaactc tccatcctca ccggagttga
    38701 gctggttgtc aaacgtggcg agaccatcgc actggtgggc gagtcgggat cgggtaagtc
    38761 aaccttgctg gcgatcctcg ccgggcttga tgacggcagc agtggcgaag tgagtctggt
    38821 gggacaaccg ctacataata tggacgaaga agcgcgggca aagttgcgcg cgaagcacgt
    38881 cggctttgtt tttcagtcat ttatgttaat tcctaccctt aacgcgctgg aaaacgtcga
    38941 gcttccggct ctgctgcgcg gtgagagtag cgcggaaagt cgtaacgggg cgaaagcgtt
    39001 gctcgaacag ttagggctgg gtaaacgtct ggatcatctt ccggcacagc tttccggcgg
    39061 tgaacagcaa cgagtggcgc tggcacgagc ctttaatggt cgacctgatg tgctgtttgc
    39121 cgacgaaccc accggcaacc ttgaccgcca gacgggcgat aaaattgccg acctgctgtt
    39181 ttccctcaac cgtgaacatg gcaccacgtt gattatggtg acccacgacc tgcaactggc
    39241 ggcacgctgc gaccgctgct tacggctggt gaacgggcag ttgcaggagg aagcatgatt
    39301 gcacgttggt tctggcgcga atggcgttcg ccgtcgctat taattgtctg gctggcgcta
    39361 agcctggcgg tggcctgcgt gctggcgctg ggcaatatca gcgatcgcat ggagaagggc
    39421 ttaagccagc aaagccgtga gtttatggcg ggcgatcggg cgttgcgcag ttcacgcgaa
    39481 gtgccgcaag cgtggctgga ggaagcgcaa aagcgcggcc tgaaagtcgg caagcagctg
    39541 actttcgcca caatgacctt tgcaggcgac acaccgcagc tggcgaacgt caaagcggtg
    39601 gatgatatct acccgatgta tggcgatctg caaactaatc cccctggcct gaaaccgcag
    39661 gcgggcagcg tattgctggc cccacgcctg atggcactgc ttaacctgaa aacgggcgac
    39721 accattgacg tgggcgatgc caccttgcgg attgccggag aagtgattca ggaaccggat
    39781 tccggtttta accccttcca gatggctccg cgtctgatga tgaatctggc ggatgtcgat
    39841 aaaaccggag ccgtgcagcc ggggagtcgg gtcacctggc gttataaatt cggcggcaac
    39901 gagaaccagc tcgacggcta tgagaaatgg ttgttacctc agcttaaacc cgaacaacgc
    39961 tggtacggtc tggaacagga cgaaggcgcg ctggggcgat cgatggaacg ctcgcaacag
    40021 ttcctgctgc tttcggcgct tctgaccttg ctgctggcag tggcagcggt ggcggtagcg
    40081 atgaatcatt actgtcgcag tcgctacgat ctggtggcga tcctcaaaac gctgggggca
    40141 gggcgagcgc aactgcgtaa gctaatcgtc ggtcagtggt tgatggtgct gacgctttca
    40201 gccgttaccg gtggggccat aggcctgttg ttcgaaaacg tgttgatggt gctgctcaag
    40261 cccgttctgc ctgctgcact accgccagcc agcctctggc cgtggctgtg ggcgcttggc
    40321 accatgacgg tcatctcgct gctggtgggg ctacgaccat atcgcttgtt gctggcaacg
    40381 cagcctttac gcgtattacg taatgatgtg gtagcgaacg tctggccgct gaagttttat
    40441 ctgccgattg tcagtgtggt ggttgtgctg ctgctcgccg gattaatggg tggcagcatg
    40501 ctgctttggg cggtgctggc gggcgcggta gtactggctt tgctgtgcgg tgtgctgggc
    40561 tggatgctgc tgaatgtact tcgccgcatg acgctgaaat cgctgcctct gcgcctggcg
    40621 gttagccgcc tgttacgtca gccgtggtca acgttaagtc agctttcggc attttcgctc
    40681 tcctttatgc tgctggcact gctgctggtg ttgcgtggcg atctgctcga ccgctggcag
    40741 cagcagctac ctccagaaag cccgaactac tttttaatta acatcgccac agaacaggta
    40801 gcaccgctaa aagcgttcct cgcggaacat cagatagtcc cggaatcgtt ttatccggtg
    40861 gtgcgggcgc ggctgacggc gattaacgat aagccgacag aaggtaatga agatgaggcg
    40921 cttaaccgcg aactcaatct tacctggcaa aatacgcggc ccgatcataa tccgattgtc
    40981 gccggtaact ggccgccaaa agccgatgaa gtgtcgatgg aagaggggct ggcgaaacgc
    41041 ttaaacgttg ccctcggtga taccgtgact tttatgggcg atacccagga gttccgcgct
    41101 aaagtgacca gcctgcgcaa agtggactgg gaaagtctgc ggcctaattt ctattttatt
    41161 ttccctgaag gggcattaga cgggcaaccg cagagctggc ttaccagttt ccgctgggag
    41221 aatggcaacg gcatgttgac acaactcaac cgccagttcc cgaccattag cctgttagat
    41281 attggcgcga ttttaaaaca ggtcggtcag gtgctggagc aggtaagtcg ggcgctggaa
    41341 gtgatggtgg tactggtcac cgcctgcggt atgttgctgt tgctggcaca ggtgcaggtg
    41401 ggaatgcgtc agcgtcatca ggagctggtg gtgtggcgca cactcggtgc ggggaaaaaa
    41461 ctgctgcgta ccacgttgtg gtgtgagttc gccatgcttg ggtttgtttc cggcctggtg
    41521 gccgcaattg gtgcggaaac ggcgctggca gtgttgcagg cgaaagtgtt tgattttccg
    41581 tgggagccag actggcgatt gtggattgtt ctgccgtgca gcggagcgct gctgctgtcg
    41641 cttttcggcg gctggctggg tgcgcgactg gttaagggta aggcgctgtt caggcagttt
    41701 gcggggtgat gagagtaaat aaggggcgtt ctggttgaat ggaacgcctt gtttaaatta
    41761 attctacaat atgtttcatt gatgatgtta ttgaattggt gatttcctat ctttctattg
    41821 ctgatattaa tctgaatcgg tggagtttat tgattttaaa tatagcccta caaaaataac
    41881 tcagactaat aaaatcat
//
LOCUS       DAPHKZ010000027        41888 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.027, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000027 DAPHKZ010000000
VERSION     DAPHKZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41888
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.027"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            212..982
                     /locus_tag="RH288_001568"
     CDS             212..982
                     /locus_tag="RH288_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HDV4030638.1"
                     /translation="MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMD
                     SVESSISSNAIVLTTIKDGQCLTSTRKNHDRGINMHVVTEVQHIVILAEHHLLDYKGV
                     EKRFSQIQPLRYPRWLVALMVGLSCACFCKLNKGGWDGAVITFFASTAAMYIRQLLAQ
                     RHLHPQINFCLTAFAATTISGLLLQLPTFSNTPTIAMAASVLLLVPGFPLINAVADMF
                     KGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV"
     gene            973..1446
                     /locus_tag="RH288_001569"
     CDS             973..1446
                     /locus_tag="RH288_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HDV4030639.1"
                     /translation="MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAI
                     GHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV"
     gene            1554..2093
                     /gene="dnaT"
                     /locus_tag="RH288_001570"
     CDS             1554..2093
                     /gene="dnaT"
                     /locus_tag="RH288_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HDV4030640.1"
                     /translation="MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYA
                     VTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFI
                     RLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
                     RDVNTVSEPDSQIPPGFRG"
     gene            2096..2833
                     /gene="dnaC"
                     /locus_tag="RH288_001571"
     CDS             2096..2833
                     /gene="dnaC"
                     /locus_tag="RH288_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HDV4030641.1"
                     /translation="MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAAL
                     ERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASF
                     IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
                     SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVM
                     DRMRLGNSLWVIFNWDSYRSRVTGKEY"
     gene            2882..3376
                     /locus_tag="RH288_001572"
     CDS             2882..3376
                     /locus_tag="RH288_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HDV4030642.1"
                     /translation="MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNS
                     TTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQVLE
                     KLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGL
                     NFIS"
     gene            3630..5921
                     /gene="opgB"
                     /locus_tag="RH288_001573"
     CDS             3630..5921
                     /gene="opgB"
                     /locus_tag="RH288_001573"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HDV4030643.1"
                     /translation="MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNIT
                     LFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRR
                     HHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDP
                     KLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIAAFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNY
                     LGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELA
                     LSTDWCVSQGQLGGQQIVQHVDKTTWKGKTAFKDTVIDIARYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITA
                     KAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVEREG"
     gene            complement(6060..7082)
                     /gene="lgoD"
                     /locus_tag="RH288_001574"
     CDS             complement(6060..7082)
                     /gene="lgoD"
                     /locus_tag="RH288_001574"
                     /EC_number="1.1.1.414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418778.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-galactonate oxidoreductase"
                     /protein_id="HDV4030644.1"
                     /translation="MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDI
                     HAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGR
                     TNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
                     APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDF
                     DAQLRAQFGGSLAQKVIDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHK
                     KETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLAETYERDVINNRELI
                     KGVITF"
     gene            7221..8135
                     /locus_tag="RH288_001575"
     CDS             7221..8135
                     /locus_tag="RH288_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313344.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDV4030645.1"
                     /translation="MSRSQNLRHNVINQVIDDMARGHIPSPLPSQSALAEMYNISRTT
                     VRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACTTASMSEQNKVFEQAFFTMINQR
                     QLRPGETFSELQLARAAGVSPVVVREYLLKFGRYNLIQSEKRGQWSMKQFDQSYAEQL
                     FELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHS
                     LLLSAADNIFFDQSLEIISVIFHFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLD
                     ATLALRNHLNSAKQSMIRSINENTRYAH"
     gene            8349..9710
                     /locus_tag="RH288_001576"
     CDS             8349..9710
                     /locus_tag="RH288_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4030646.1"
                     /translation="MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAM
                     LLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGTLLSVFSLAYGIAQLPCGPLLD
                     RKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
                     IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYR
                     NREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLY
                     LAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKIC
                     IIAGMFCSAAFTLVVPQATTSMTAVLLIGTALFCIHFAGTSCWGLIHVAVASRMTASV
                     GSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDP
                     RKD"
     gene            complement(9759..11423)
                     /gene="tsr"
                     /locus_tag="RH288_001577"
     CDS             complement(9759..11423)
                     /gene="tsr"
                     /locus_tag="RH288_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HDV4030647.1"
                     /translation="MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQ
                     TIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAE
                     KNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
                     DGFEKQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASL
                     VAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA
                     IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSAS
                     ETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQ
                     GRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVT
                     RVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRL
                     TEAVAVFRIQQQQQQQRETSAVVKTVTPAAPRKMAVADSGENWETF"
     gene            11605..12468
                     /locus_tag="RH288_001578"
     CDS             11605..12468
                     /locus_tag="RH288_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDV4030648.1"
                     /translation="MAYSIDIISCITERFMALTATEKRIAQFILDDVSAAVELPIAEL
                     ARLTQTSQASVTRFARALGCKDVRELKVKLAQSLAVGQRFILDVPDLDGVQGIYEAII
                     SVLETHRRSLDMNAISQAVSWLSQARQILALGTGGGSTICSQEIQYRLFRLGLPVVSQ
                     NDALMMRMMCSAVMPQDVVIVLSLGGYTPEIIESAAIARQYGARVIAITPAQTPLAEQ
                     VDLVLPLLVQESDYIFKPTPSRYAMLAMVDVLATELAMANKAQAKDRLRRIKLVLDSH
                     RGGANRQPLGD"
     gene            complement(12478..13947)
                     /locus_tag="RH288_001579"
     CDS             complement(12478..13947)
                     /locus_tag="RH288_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDV4030649.1"
                     /translation="MNSHIFLVGFIIYAIAMIWLGWFVSRNQKSGEDFLLGGRSLPLF
                     LTLGSTVATMVGTGSSMGAVGFGYSNGWAGMLYGVGGAVGILLVAWLFAPVRKLRFMT
                     MSEEISYYTGGSHLIKNIVGLMIFIASIGWLGAHILGGSMYLAWATGIDLTVAKLIIA
                     LAFAIYVIIGGYSAVVWTDTIQALILFFGFILMAILAVVHVGGWSAIEQAMDPKAMSL
                     FAIDKMGVLPALSLALVIGVGVLATPSYRQRIYSGKDVPSVRRSFVITGVLYLFFSIL
                     PAIIGMAAFTMNPNLENSNYAFLFATSFLPAILGLVVLIAGLSATMSSASSDAIAAVA
                     IMMRDVYTMITGRMPPEDKAITYSRWMLTFVIGLALVFALTSNDIISYITKMISMLMS
                     GLFICSILGRFWLRFNWQGALAALVSGMVMSIVVLMNADWLAYWGNPCIPSVLGSLVA
                     GVLVTLVTPASQVSREEALAIITNERENQSVVITKPEEA"
     gene            complement(14050..14439)
                     /locus_tag="RH288_001580"
     CDS             complement(14050..14439)
                     /locus_tag="RH288_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDV4030650.1"
                     /translation="MNIKRYGTEGGTGTGGQHLPFARAVEAGGWLYVSGQTPMKNGEV
                     VEGGIVEQSRLAIQNCVDIMTEAGYSLADVVHVKVILTDARYFQSFNKVFREFFGENP
                     PARICCVADLVVDCKVEVDVTCYNATR"
     gene            complement(14449..15891)
                     /locus_tag="RH288_001581"
     CDS             complement(14449..15891)
                     /locus_tag="RH288_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004100781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDV4030651.1"
                     /translation="MQVDWLIKNVTVIDGSGGPEFRGDVAITGDRIVDIAPALNVTAQ
                     QVIDGEGRVLAPGFIDVHTHDDINVIRIPEYLPKISQGITTVIVGNCGISAASAKMKG
                     EVPDPMNLLGEAEHFIYPTVESYAQAVEAARPSLNVGTLIGHTALRNNHMDDLFRPAT
                     VDEIAAMRADLRLALSQGALGLSSGLAYATAFQATTEEVMALAEELAGEKGVYTTHLR
                     SEFKPILDALDEAFRIGRHGKVPVVVSHHKCAGAKNWGRTKETLAFFDQMRQHQEIGC
                     DVYPYSASSSTLDLKQVTDEFDIVITWSQTHPQQAGKTLAQIAIDWQMSMLEAAKLLM
                     PAGAIYYNMDERDVRRVLSYPVSMIGSDGLPNDPMPHPRLWGAFPRVLGHYCRDEGLF
                     PLTTAIHKMTGLSASRFRLPQRGLVKVGYFADLVLFDPQTIRDVASFSDPKRPADGIE
                     AVMVNGVMSYGRDKHITGRAGRFLRRQTSH"
     gene            16092..17312
                     /locus_tag="RH288_001582"
     CDS             16092..17312
                     /locus_tag="RH288_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid deaminase"
                     /protein_id="HDV4030652.1"
                     /translation="MKYHSEPLVPHKSALMQMPANLLAEDVCLPAAIIKKQALENNIT
                     WMQRYADARGVSLAPHGKTTMTPWIFQAQQAAGAWAIGVGSAWQAGAAMASGIQRVLM
                     VNQLVGKANMQLIAQLQQHYPTVDFICCIDSIENARALSAFFASQQQTLNVMIELGVP
                     GGRCGCRSTDAALALAKQAAQLPGLRLRGLELYEGVLHGDDPQPQVEALLRDAAQLAC
                     DMANLVDGEFILTGAGTVWYDVVCNIWLAAEKPDNCRIVIRPGCYITHDTGIYDAAQQ
                     QLLARDPVACDLAGDLTSALELVAMVQSVPEADRAVVNFGKRDCAFDAGLPQPVAHYR
                     NGKSLAFDPQAIRSTGIMDQHCMLQLSANSDVQVGDILVFGTSHPCLTFDKWKTLLLA
                     DDDYNVLAELDTLF"
     gene            17580..19730
                     /gene="btsT"
                     /locus_tag="RH288_001583"
     CDS             17580..19730
                     /gene="btsT"
                     /locus_tag="RH288_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HDV4030653.1"
                     /translation="MDTKKIFKHIPWVILGIIGAFCLAVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNP
                     QMEGFFYMASQYKEKIANGTDLTAQQIANMNHIVVNNYTNAGLSILFLIVVYSIIFYG
                     FKTWLKVRNSDKRTDKETPYVPIPEGGVKISSHH"
     gene            19861..20064
                     /locus_tag="RH288_001584"
     CDS             19861..20064
                     /locus_tag="RH288_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HDV4030654.1"
                     /translation="MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSY
                     EEFFRERQNARYGGDGKGGMRCC"
     gene            20075..21031
                     /gene="yjiA"
                     /locus_tag="RH288_001585"
     CDS             20075..21031
                     /gene="yjiA"
                     /locus_tag="RH288_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418772.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HDV4030655.1"
                     /translation="MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMA
                     DPGPIIQTFFSHEVLCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
                     DVAGEAEKLHERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVVSTKPRFHFIA
                     DKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDEKPHSTMVFIGIQLPEEEIRAAFAGLRK"
     gene            complement(21077..21991)
                     /gene="mrr"
                     /locus_tag="RH288_001586"
     CDS             complement(21077..21991)
                     /gene="mrr"
                     /locus_tag="RH288_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine/cytosine-specific restriction
                     endonuclease Mrr"
                     /protein_id="HDV4030656.1"
                     /translation="MTVPTYDKFIEPVLRYLATKPEGAAARDVHEAAADALGLDDSQR
                     AKVITSGQLVYKNRAGWAHDRLKRAGLSQSLSRGKWCLTPAGFDWVASHPQPMTEQET
                     NHLAFAFVNVKLKSRPDAVDLDPKADSPDHEELAKSSPDDRLDQALKELRDAVADEVL
                     ENLLQVSPSRFEVIVLDVLHRLGYGGHRDDLQRVGGTGDGGIDGVISLDKLGLEKVYV
                     QAKRWQNTVGRPELQAFYGALAGQKAKRGVFITTSGFTSQARDFAQSVEGMVLVDGER
                     LVHLMIENEVGVSSRLLKVPKLDMDYFE"
     gene            22179..25691
                     /gene="hsdR"
                     /locus_tag="RH288_001587"
     CDS             22179..25691
                     /gene="hsdR"
                     /locus_tag="RH288_001587"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system
                     endonuclease"
                     /protein_id="HDV4030657.1"
                     /translation="MMNKSNFEFLKGVNDFTYAIACAAENNYPDDPNTTLIKMRMFGE
                     ATAKHLGLLLNIPPCENQHDLLRELGKIAFVDDNILSVFHKLRRIGNQAVHEYHNDLN
                     DAQMCLRLGFRLAVWYYRLVTKDYDFPVPVFVLPERGENLYHQEVLTLKQQLEQQVRE
                     KAQTQAEVEAQQQKLVALNGYIAILEGKQQETEAQTQARLAALEAQLAEKNAELAKQT
                     EQERKAYHKEITDQAIKRTLNLSEEESRFLIDAQLRKAGWQADSKTLRFSKGARPEPG
                     VNKAIAEWPTGKDETGNQGFADYVLFVGLKPIAVVEAKRNNIDVPARLNESYRYSKCF
                     DNGFLRETLLEHYSPDEVHEAVPEYETSWQDTSGKQRFKIPFCYSTNGREYRATMKTK
                     SGIWYRDVRDTRNMSKALPEWHRPEELLEMLGSEPQKQNQWFADNPGMSELGLRYYQE
                     DAVRAVEKAIVKGQQEILLAMATGTGKTRTAIAMMFRLIQSQRFKRILFLVDRRSLGE
                     QALGAFEDTRINGDTFNSIFDIKGLTDKFPEDSTKIHVATVQSLVKRTLQSDEPMPVA
                     RYDCIVVDEAHRGYILDKEQTEGELQFRSQLDYVSAYRRILDHFDAVKIALTATPALH
                     TVQIFGEPVYRYTYRTAVIDGFLIDQDPPIQIITRNAQEGVYLSKGEQVERISPQGEV
                     INDTLEDDQDFEVADFNRGLVIPAFNRAVCNELTNYLDPTGSQKTLVFCVTNAHADMV
                     VEELRAAFKKKYPQLEHDAIIKITGDADKDARKVQTMITRFNKERLPNIVVTVDLLTT
                     GVDIPSICNIVFLRKVRSRILYEQMKGRATRLCPEVNKTSFKIFDCVDIYSTLESVDT
                     MRPVVVRPKVELQTLVNEITDSETYKITEADGRSFAEHSHEQLVAKLQRIIGLATFNR
                     DRSETIDKQVRRLDELCQDAAGVNFNGFASRLREKGPHWSAEVFNKLPGFIARLEKLK
                     TDINNLNDAPIFLDIDDEVVSVKSLYGDYDTPQDFLEAFDSLVQRSPNAQPALQAVIN
                     RPRDLTRKGLVELQEWFDRQHFEESSLRKAWKETRNEDIAARLIGHIRRAAVGDALKP
                     FEERVDHALTRIKGENDWSSEQLSWLDRLAQALKEKVVLDDDVFKTGNFHRRGGKAML
                     QRTFDDNLDTLLGKFSDYIWDELA"
     gene            25892..27481
                     /gene="hsdM"
                     /locus_tag="RH288_001588"
     CDS             25892..27481
                     /gene="hsdM"
                     /locus_tag="RH288_001588"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system
                     methyltransferase"
                     /protein_id="HDV4030658.1"
                     /translation="MNNNDLVAKLWKLCDNLRDGGVSYQNYVNELASLLFLKMCKETG
                     QEAEYLPEGYRWDDLKSRIGQEQLQFYRKMLVHLGEDDKKLVQAVFHNVSTTITEPKQ
                     ITALVSNMDSLDWYNGAHGKSRDDFGDMYEGLLQKNANETKSGAGQYFTPRPLIKTII
                     HLLKPQPREVVQDPAAGTAGFLIEADRYVKSQTNDLDDLDGDTQDFQIHRAFIGLELV
                     PGTRRLALMNCLLHDIEGNLDHGGAIRLGNTLGSDGENLPKAHIVATNPPFGSAAGTN
                     ITRTFVHPTSNKQLCFMQHIIETLHPGGRAAVVVPDNVLFEGGKGTDIRRDLMDKCHL
                     HTILRLPTGIFYAQGVKTNVLFFTKGTVANPNQDKNCTDDVWVYDLRTNMPSFGKRTP
                     FTDEHLQPFERVYGEDPHGLSPRTEGEWSFNAEETEVADSEENKNTDQHLATSRWRKF
                     SREWIRTAKSDSLDISWLKDKDSIDADSLPEPDVLAAEAMGELVQALSELDALMRELG
                     ASDEADLQRQLLEEAFGGVKE"
     gene            27478..28872
                     /gene="hsdS"
                     /locus_tag="RH288_001589"
     CDS             27478..28872
                     /gene="hsdS"
                     /locus_tag="RH288_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system
                     specificity subunit"
                     /protein_id="HDV4030659.1"
                     /translation="MSAGKLPEGWVIAPVSTVTTLIRGVTYKKEQAINYLKDDYLPLI
                     RANNIQNGKFDTTDLVFVPKNLVKESQKISPEDIVIAMSSGSKSVVGKSAHQHLPFEC
                     SFGAFCGVLRPEKLIFSGFIAHFTKSSLYRNKISSLSAGANINNIKPASFDLINIPIP
                     PLAEQKIIAEKLDTLLAQVDSTKARFEQIPQILKRFRQAVLGGAVNGKLTEKWRNFEP
                     QHSVFKKLNFESILTELRNGLSSKPNESGVGHPILRISSVRAGHVDQNDIRFLECSES
                     ELNRHKLQDGDLLFTRYNGSLEFVGVCGLLKKLQHQNLLYPDKLIRARLTKDALPEYI
                     EIFFSSPSARNAMMNCVKTTSGQKGISGKDIKSQVVLLPPVKEQAEIVRRVEQLFAYA
                     DTIEKQVNNALARVNNLTQSILAKAFRGELTAQWRAENPDLISGENSAAALLEKIKAE
                     RAASGGKKASRKKS"
     gene            29100..29441
                     /gene="symE"
                     /locus_tag="RH288_001590"
     CDS             29100..29441
                     /gene="symE"
                     /locus_tag="RH288_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418767.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease SymE"
                     /protein_id="HDV4030660.1"
                     /translation="MTDTHSIAQPFEAEVSPANNRHVTVGYASRYPDYSRIPAITLKG
                     QWLEAAGFATGTAVDVKVMEGCIVLTAQPPAAEESELMQSLRQVCKLSARKQKQVQAF
                     IGVIAGKQKVA"
     gene            29603..30981
                     /gene="mcrB"
                     /locus_tag="RH288_001591"
                     /pseudo
     CDS             29603..30981
                     /gene="mcrB"
                     /locus_tag="RH288_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418766.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-methylcytosine-specific restriction
                     endonuclease subunit McrB"
     gene            30981..32027
                     /gene="mcrC"
                     /locus_tag="RH288_001592"
     CDS             30981..32027
                     /gene="mcrC"
                     /locus_tag="RH288_001592"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methylcytosine-specific restriction
                     endonuclease system specificity protein McrC"
                     /protein_id="HDV4030661.1"
                     /translation="MEQPVIPVRNIYYMLTYAWGYLQEIKQANLEAIPGNNLLDILGY
                     VLNKGVLQLSRRGLELDYNPNTEIIPGIKGRIEFAKTIRGFHLNHGKTVSTFDMLNED
                     TLANRIIKSTLAILIKHEKLNSTIRDEARSLYRKLPGISTLHLTPQHFSYLNGGKNTR
                     YYKFVISVCKFIVNNSIPGQNKGHYRFYDFERNEKEMSLLYQKFLYEFCRRELTSANT
                     TRSYLKWDASSISDQSLNLLPRMETDITIRSSEKILIVDAKYYKSIFSRRMGTEKFHS
                     QNLYQLMNYLWSLKPENGENIGGLLIYPHVDTAVKHRYKINGFDIGLCTVNLGQEWPC
                     IHQELLDIFDEYLK"
     gene            complement(32084..38428)
                     /locus_tag="RH288_001593"
     CDS             complement(32084..38428)
                     /locus_tag="RH288_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001605447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDV4030662.1"
                     /translation="MTTRYFSSLIEQSLSRSTEATLSIMGVTNPQLREHLAQQMGADC
                     GKPGSFLASPVFQQMFGWKESNHTMRSLTEGNALLSKAVVDSLDDQNNGRYRFGADWR
                     PFTHQLASWKALLEKKHSVVVTSGTGSGKTECFMVPVLEDLYRELHENGNNPLVGVRA
                     LFLYPLNALINSQRERLDAWTRGFGTGIRYCLYNGNTENLHASVKSEQAKRPNEVLSR
                     EKMREEPAPILVTNGTMLEYMMVRQVDAPIIQQSKAQKSLRWIVLDEAHTYVGSQAAE
                     LALQLRRVMTAFGVTPDDVRFVATSATIAGSDAEKQLKKFLSELSGIPQERIDVLDGS
                     RVIPELEPSKNVSVPLDEIEQIPDLDLRDKNDNKIKGISPERFYALTHSPEARYIREM
                     LVKQPNPMKLDEITERLHVLTKQHYSQQEVLRWIDVCSGTQPNAKDPAFLKVRAHIFQ
                     RNTQGIWACVDKDCRLKHGTPLDKGWPFGYVYVNQRQNCDCGSPVYEVAFCNDCNEPH
                     LLARDKKGKLVQWENKGGDEFSLQDEVPVEHDATEEKVEKENSFQPPLIIAAGETSEA
                     GYTLQRLDRQTRRIGVINNDSIPLIINDIEQVCSASGCGYRGMSGKQPFRRALLGGPF
                     YVTNIVPTVLEYCQDFTSDEGKEGVGPDSLPGRGRRLITFTDSRQGTARMAVRMQQEA
                     ERSRLRGSVVEILSWHQRTQTSTAPNANADLEKLAARAKQAREQAEEYRSWGMPDQAK
                     LSQAQAEQLEQAYQAATGGKAATILVSRTWTEMVNELKERADIRGPVLQYNHYLKPEV
                     FNENGGPLKLSEMLLFREFMRRPKRTNSLETQGLVQVGYQGLEKIHKSPLHWQEKGLT
                     LDDWRDFLKVTLDHYVRESNFTQLDDELKNWIGSRFSSKFVRNPESKDPEDNQNRRWP
                     QIRNGNVSHRLAKLLMLGAGFKTVNAATIDIINTWLKEAWAQLTGPLAVLKPDGNRFY
                     LPKEHMTFSLITDAWICPVTNKILDTAFKGLTPYLPTHISFEHLTLAQYDTFVAQKVT
                     MPEIWKLDRSQEDYAEGLAKARDWVSHDPLIAQLRSENVWTDINDRVVEGGFYYRTAE
                     HSAQQSSERLQSYEKMFKNGQLNVLNCSTTMEMGVDIGGITAVVMNNVPPHPANYLQR
                     AGRAGRSKESRAISYTLCKGNPHDQQVFANPLWPFETMIPAPMVAMNSARLVQRHVNA
                     LLLSDFLCNVIGETDKEKTSLDSLWFFGEDDGQSKCERFKIWLERPVLDIDTALERLV
                     KGTALHGARAEYLRDKTINAITFLQQRWLSVYRDLVTQERESQPQTPYRKRIELEKKR
                     HCGEYLLRDLAARTFLPGYGFPTDVVTFDNFTMEDYIREKSQKSRDKKDREDNVSRYK
                     GLPSRNLGVAIREYAPGAEIILDGRVFRSAGVSLHWHNINADTNEAQRLDCAWRCHKC
                     GTIGYEEGMSSSGMLFCSNSACGEKIIMDNRRQVLQPAGFVTDAHAPVTNNIETMKFV
                     PVVPAWVFVKAEPVPLPNPLMGYMASGADGHVFQQSLGEGGHGYALCLSCGRAESMLN
                     ENDAPKSMEAHYPPRPGKADRDSQNHRLICPGSTALMKNVTLGALARTDVFEMVLRKP
                     QNGEYLPDNTEEGRIVAMTLAVALRQALAGVLGISAAELGYSVRPVRLEDGQSVLAVQ
                     LYDVISGGAGFASSAPVHIEAILQGMVKQLGCRHCETACSECLLDSQTRHDHDLLDRK
                     AALAWLGDDFTYYIGLPDEETFSLPDARYCPGAIGDTIRRAINEGAEKLTLWMTGAPN
                     EWDLYARQFRAAVQNYRLKDNVEVDLVIPTGVDDPDLLHELSQFTALGVRLCHVEQDL
                     QLPIVAQVTFTDRVMTLASRSQQATIPGPEWHLNDELVVRSLGYKTVELNEFILPAKA
                     TNAVERVKDIQIHKQLNGPLSQFGQRFWDVLFNDHEEAQSLMNNTRITGVHYTDRYLQ
                     NPVALALLGSILRPLKTKLTDGAEVTLDTLFKDKDRPGNRPFHDWMSIADFQDFADQW
                     FAAALGRPVELTVFDSPRDIPHHRKLTVTFEDGQVLKIRFDQGMGYWRINFSSQWHYF
                     DFRDDVSFQLVKMAQACKEGNVANSEESWATDVLVEVIAS"
     gene            complement(38441..41731)
                     /locus_tag="RH288_001594"
     CDS             complement(38441..41731)
                     /locus_tag="RH288_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030663.1"
                     /translation="MGQSEYISWVKCTSWLSNFVNLRGLRQPDGRPLYEYHATNDEYT
                     QLTQLLRAVGQSQSNICNRDFAACFVLFCSEWYRRDYERQCGWTWDPIYKKIGISFTA
                     TELGTIVPKGMEDYWLRPIRFYESERRNFLGTLFSEGGLPFRLLKESDSRFLAVFSRI
                     LGQYEQAKQSGFSALSLARAVIEKSALPTVFSEDTSVELISHMADNLNSLVLTHNLIN
                     HKEPVQQLEKVHPTWRSEFPIPLDDETGTHFLNGLLCAASVEAKPRLQKNKSTRCQFY
                     WSEKHPDELRVIVSLPDEVSFPVTSEPSTTRFELAICEDGEEVSGLGPAYASLENRQA
                     TVRLRKSEVRFGRQNPSAGLSLVARAGGMIVGSIKLDDSEIAIGEVPLTFIVDADQWL
                     LQGQASCSVRSSDVLIVLPRDNSNVAGFDGQSRAVNVLGLKALPVKGCQDVTVTANET
                     YRIRTGREQISIGRFALNGKRASWVCHPDETFIGVPKVISTLPDIQSIDVTRYLSGIS
                     IEQCHIQEMLGAQYLSIRNSKNETLLRRKIGILPADFSIEIKGGIHANEGTIVITTQH
                     PCVAKLKDKTLEATRKRTEGRTEIQLKAEGVPPAFITLQVLPNLAADPIDIELPFPAK
                     GCLALDVNGRPLDKNITLHDLLGSRAFLFSRNGEPTRYTLQLHLRSVSGLQAWHEWCY
                     TALSDRPVELNLYSLREHIENLISLEAGIDQVVEMRITGAGVVMAWQIRRYKYSLRYD
                     YEKELLLSQSVNHRAGQIPSPVIMLLSEPERKSIPLASRMSEGVPVGEYELSSIVNKN
                     GPWLVVPKPGEEMAFRPCFIRGESSLPVEESNIRSLQKATQLFNPQAEVNTITLVLGQ
                     MANDPAHSGWQFMRSLYDQFGYLPLATFEVWRALVQHPQALAMSLFKFEMSAEYLSRI
                     ENEFPILWEFFPIFEIKAASERFKLFLSQKGAPEETQKLLVTNMFQRLGLVFPTYADE
                     IEKWLSNGHLPPSIPESFVHVWYQELLREHSEAQWPEYGSKRLHSWMASQKNPVIGIN
                     PDANHRYSVALLPVFAAAVASGNASFESVFDRKPGAVFFLRQVRDFDSRWFKAIFQCS
                     LLRYVAKK"
BASE COUNT        10580 a        10882 c        10136 g        10290 t
ORIGIN      
        1 aaacaataaa ttcattatag tgataatatt catgtgatag tttgtttgcg gcgagagata
       61 attcgctttt tatcaccgag cttgtcccga taaccaggat taatcagcgc aattttgatc
      121 ttaacctacc gcaaaacaac cgtgcttcat gatacaaatg gattctcatt atctgaacaa
      181 tacgcagcac gtctatgaca aagggcgagt tatgcaaact gagcaacagc gagccgtaac
      241 acggctttgt atccagtgtg gattatttct tttgcaacat ggtgcggaaa gcgcgttggt
      301 tgatgagctt tcctcacgac tgggtcgggc gttggggatg gacagcgtcg aaagttctat
      361 ctcttcgaac gccatagtgc tgacaaccat taaagatggg caatgcctga catcgacacg
      421 taaaaatcac gatcgcggca ttaatatgca tgtggtgact gaagtccagc acattgtgat
      481 tctggcggag caccatctgc tggattacaa aggcgtagag aaacgattta gccaaattca
      541 gccattacgt tacccaagat ggctggtagc cttaatggtt ggcctttctt gtgcctgttt
      601 ctgtaaactc aataaaggtg gctgggatgg tgccgtcatc accttctttg ccagtacggc
      661 cgcgatgtat atccgccagc tgctggcaca acgtcatctt catccacaaa tcaacttttg
      721 ccttaccgct ttcgccgcca ccaccatttc cggattgctt ttgcaactcc ccactttcag
      781 caataccccc accattgcga tggccgccag cgttctgctg ctggtgccgg gctttccgtt
      841 gattaatgcc gtcgccgata tgtttaaagg ccacatcaat accggactgg cacgctgggc
      901 gatcgccagt ctgctgacac tggctacctg cgtcggcgta gtgatggcac tgacgatttg
      961 ggggctacgc ggatgggtgt gatcgaattt ctgttagcgt tggcgcagga tatgatcctc
     1021 gccgccattc ctgcggtcgg ctttgcgatg gtgttcaacg ttcccgttcg ggcgttacgc
     1081 tggtgtgcgc tgcttggcgc gattggtcat ggttcacgaa tgatcttaat gaccagcggg
     1141 ctgaatattg agtggtcaac ctttatggcc tccatgctgg tcggcaccat tggtattcaa
     1201 tggtcgcgct ggtatctggc gcatccgaaa gtgtttaccg tggcggccgt tatccctatg
     1261 ttcccgggca tatcggctta taccgcaatg atttcggcgg taaaaatcag ccagttaggt
     1321 tacagcgaac cgttgatgat taccctgtta accaactttc ttacagcttc atcgattgtt
     1381 ggtgcgttat ccatcggtct ttccattcct ggattatggt tgtaccgcaa gcgccctcgc
     1441 gtataaaatt gcctcgctta aagcacacgg atgagagaca gcctcctctc ctccgtgtgt
     1501 tactataaaa gttatctccc ttctcgttca tcgttccata tttgagaaac agtatgtctt
     1561 ccagagtttt gaccccggac gtcgttggta ttgacgccct ggtacacgat caccaaaccg
     1621 ttctggcaaa agctgaaggc ggtgtggttg ccgtatttgc taacaatgcc ccggcgtttt
     1681 atgccgtcac gcctgcacgc ctggctgaac tgctggcgct ggaagaaaag ctggcgcgtc
     1741 cgggaagcga tgtcgctctg gacgatcaac tctatcagga accgcaagcc gctcccgttg
     1801 ctgtacccat ggggaaattc gccatgtatc cggactggca acccgatgcc gattttatcc
     1861 gcctggcggc gctatggggt gtggcactaa gagagccggt gaccaccgaa gaactggcct
     1921 cattcattgc ctactggcag gcggaaggta aagtctttca ccatgtgcag tggcaacaaa
     1981 aactggcgcg cagcctgcaa atcggtcgtg ccagcaacgg cggactgccg aaacgagatg
     2041 tgaatacggt cagcgaacct gacagtcaaa ttccaccagg attcagaggg taacgatgaa
     2101 aaacgttggc gacctgatgc aacgcctgca aaaaatgatg cctgcccata tcaaacctgc
     2161 attcaaaacg ggtgaagaac tactggcctg gcagaaagaa caaggagcga tccgctccgc
     2221 cgctctcgaa cgtgaaaatc gggcgatgaa aatgcagcgc acctttaacc gctccggtat
     2281 tcggccactg catcagaact gctcctttga gaactatcgc gttgagtgtg aagggcagat
     2341 gaatgcgtta agcaaagcgc gccagtacgt cgaagagttt gacggcaaca tcgccagctt
     2401 catcttttct ggtaagccag gaaccggcaa aaaccatctg gcggcggcaa tctgcaacga
     2461 gctgctgcta cgcggtaaat ccgtattgat catcaccgtg gccgatatta tgtcggcgat
     2521 gaaagatacc ttcaggaata gcggtaccag tgaagaacaa ctgcttaacg atctgagcaa
     2581 cgttgatctg ctggtgatcg atgagatcgg cgtgcagacc gaatcgaaat acgaaaaagt
     2641 gatcatcaac cagatcgtcg atcgccgctc ttcttccaaa cgcccaaccg ggatgctgac
     2701 caacagtaat atggaagaga tgaccaagtt gctgggcgaa cgcgtgatgg accgtatgcg
     2761 cctgggtaac agtttgtggg tgatcttcaa ctgggatagc taccgtagcc gggtaacagg
     2821 taaagagtat taatccccgt ttctggcggt atactgcgac acaattccac cttgagtaat
     2881 gatgatgaaa actgttaaac atcttctgtg ctgtgccatt gccgccagcg cattaatttc
     2941 caccggggtg catgctgcgt cctggaaaga tgcgctctcc agcgccgcca gcgaacttgg
     3001 taaccaaaac agcacgacac aggaaggcgg ttggtcgctc gcgtcattaa ctaacttgct
     3061 tagcagcggg aaccaggcct taagcgcaga taacatgaac aacgccgcag gcattctgca
     3121 atactgcgcg aagcaaaagc tggcgtcggt aaccgatgcc gaaaacatca agaaccaggt
     3181 gctggaaaag ctgggcctga acagtgaaga gcaaaaagaa gacaccaact atctggatgg
     3241 cattcagggt ttgctgaaaa ccaaagatgg tcagcaactc aatctggata acatcggaac
     3301 gactccgctg gcagaaaagg tgaaaaccaa agcctgcgat ctggtgttaa agcaggggct
     3361 gaacttcatt tcctgaaccg cgaaacgccg cgttttagct gttacccggc tgacgcggct
     3421 ctctcctgcc cttttccctg cttctggacg gttttccccc tgttacacgg gaagcgaccg
     3481 cgatcaaaaa agtctgttta taaactaatt cctaacaaca tcgcattttt ttgacactag
     3541 aattgcagca atatggcgac gccattacat tgtgcttctc aaaaagctta aacgttggct
     3601 aaacggcccg gtttagtgag gatcgcccgt tgtcagaact actctctttc gccctttttc
     3661 tcgcctctgt gctgatttac gcatggaaag cgggacgtaa cacctggtgg tttgcagcca
     3721 cattaacggt gctggggcta tttgtcgttt taaatatcac cctgtttgcc agcgactatt
     3781 ttactggcga tggtattaac gacgcggttc tctatacctt aaccaacagc ctgaccggtg
     3841 ctggcgtcag caaatacatc ctgccgggta tcggcattgt gctggggctg acagcggtgt
     3901 tcggtgcgct gggctggatc ctgcgccgtc gtcgccatca tccgcaccat tttggttaca
     3961 gcctgctggc gctcttactg gcgctgggtt cggtggacgc cagcccggca tttcgtcaga
     4021 taacggaact ggtgaaatcc cagtcacgcg atggcgaccc ggactttgcg gcttattata
     4081 aagagccgtc gaaaactatc cctgacccga aactcaacct ggtttatatc tacggcgaaa
     4141 gtctcgagcg gacctatttt gataacgaag ctttcccgga tctcacgcct gaactgggcg
     4201 cgttgaaaaa tgaaggcctg gatttcagcc acacgcagca gctgccagga acggattaca
     4261 cgattgcggg catggtggct tctcagtgcg gcataccgct gtttgccccc tttgaaggca
     4321 acgcctccgc ctctgtctcc agcttcttcc cgcagaacat ctgtctgggc gatatcctga
     4381 aaaactcggg ttatcagaac tatttcgtgc agggcgcgaa tctgcgtttt gccggtaaag
     4441 atgtgttcct gaagtcgcat ggcttcgacc acttatacgg ctcagaagag ctgaaaagcg
     4501 tggtggccga cccgcactat cgcaacgact ggggattcta cgacgatacc gttctcgatg
     4561 aagcgtggaa aaagtttgaa gagctttccc gctcaggtca gcgattctca ctgtttaccc
     4621 tgacagtcga tacccatcac ccggatggtt ttatctcgcg tacctgtaac cgcaaaaaat
     4681 atgattttga cggtaagccg aaccagtcat tcagcgcggt aagttgcagc caggagaata
     4741 tcgcggcgtt tatcaacaaa atcaaagcgt caccgtggtt taaagatacc gtcatcgtcg
     4801 tctcttctga ccatttagcg atgaacaaca cggcgtggaa atacctcaat aagcaggatc
     4861 gcaataacct gttttttgtc atccgtggcg acaagccgca gcaagagacg ctggcagtga
     4921 agcgtaacac gatggataac ggcgcgacgg tgctggacat tctcggtggc gataactatc
     4981 tcggacttgg tcgtagcagt ttatccgggc agtcgatgtc ggaaatcttc ctcaatatca
     5041 aagagaaaac attggcgtgg aagccggata tcatccgcct gtggaaattc cctaaagaga
     5101 tgaaagagtt caccatcgac cagcagaaaa acatgattgc cttctcgggt agccatttcc
     5161 gtttgccgct gctgttgcgg gtttcagaca aacgcgtgga accgctgccg gaaagcgaat
     5221 actcagcacc gctgcgtttc cagctggccg atttcgctcc acgcgacaat ttcgtctggg
     5281 ttgaccgttg ctataagatg gcacaactct gggctccgga actggcactt tccaccgact
     5341 ggtgtgtctc gcaagggcag cttggcggtc agcaaattgt ccagcatgtt gacaaaacaa
     5401 catggaaggg caaaacggca tttaaagata cggtcatcga catagcgcgt tacaaaggca
     5461 atgtcgatac gctgaagatt gttgataacg atattcgcta caaagccgac agtttcatct
     5521 ttaacgtcgc cggtgcgcca gaagaggtga aacagtttag cggaatttcc cgtccggagt
     5581 cgtggggccg ctggtccaac gcgcaactgg gcgatgaagt aaaaatcgag tacaagcatc
     5641 cgctgccgaa gaaatttgac ctggtgatta ccgccaaagc atacggcaat aacgccagcc
     5701 gtcctattcc ggtacgcgta ggcaatgaag aacaaaccct tgtgctgggc aatgaagtga
     5761 ccaccaccac actgcatttc gataacccaa ccgatgccga cacactggta attgtgccgc
     5821 cggaacctgt ctcaaccaac gaagggaata tcctcggaca ctcgccgcgt aagctcggga
     5881 tcggcatggt ggaaattaaa gtggtggaac gtgaaggata attcctgact gatgtgtagg
     5941 tcgcataagg tgcgacctac acaccttctg cggcctacaa aacatcattg agaaacagaa
     6001 aaaaacagcg cccaacactt ccccggacgc tgcatggcaa ctttaataat ctcgccttat
     6061 cagaaagtaa ttacaccctt aatcaactca cgattgttaa tcacatcgcg ctcgtaggtt
     6121 tctgccagcg tggcgaacgg atagcgatgg gttaacatca tgtcagcagt gatttttcct
     6181 tccgccatca gtcgaccgac tttagcaaaa tcttccggcg tggcgttgcg gctacccatc
     6241 atcgtcgttt cttttttatg gaattccgga tcggagaact gcaactcacc tttaaacagg
     6301 ccgacaaata ccaccgtgcc gccgtgacga atcaaattca cggtgttatt catcgcatgt
     6361 tgattacctg tcgcgtcgat cactttctgc gccagcgaac caccaaactg cgcccgtagc
     6421 tgcgcgtcaa aatcttcggc tgacgggtcc agtaaaggta attccagacg cgttgccaca
     6481 tgttcacggc gcgccggact ggtatccgcc accaccacct gtgcgccatc ggctttagcg
     6541 attgccgccg cgcccagacc gattggcccc gccccgacca ccagcacctg ctcgccggga
     6601 gcaatggctg cgcgacgcac cgcatgagcg ctaatagcga aaggttcaat caatgctgcc
     6661 gcctgcgggt caataccgtc tgcgggcaaa atgttcgcca ccggcacgct caaatactca
     6721 ctaaaaccgc catcctgatg cacgccaatg actgaaattt tttcacagca attggtacgc
     6781 ccgcttttac acgccggaca ttgctgacag gcaacataag ggatcacagc aacttgctga
     6841 ccatttttaa gatcagcaat atttttaccc agcccaacaa tctccccaca tatttcatgg
     6901 cctaaaaccc gtggataact aaaaaatggt tgatttccac cccaggcatg aatatcggta
     6961 ccgcaaatcc cgacagactt aatttttatt aatgcttcat tgtcacccgg aataggtatc
     7021 tcgcgttgtt tccagactaa ttctttcggc tgctggcaaa ttaaaacatt catcgtagac
     7081 atgattcggc tctccatttt ttgttgcctt agatatcaat gaaaatgaaa aatggcagcg
     7141 gaacggaaaa tctgttttgt gaaaacacac gcataaaaat gttttaaatc gggttttaat
     7201 ggactcacaa ggaggaaaat atgagtcgtt cacaaaattt acgccacaat gtgattaacc
     7261 aggtcattga tgatatggcg cggggtcata tcccttcccc acttccatcg caaagtgcgc
     7321 tggcggaaat gtacaacatc agccgcacta cagtgcgtca tattctcagc cacttacgcg
     7381 aatgcggcgt cttaacgcag gttggaaacg actatgtgat tgcgcgtaaa cctgaccatg
     7441 atgacggttt cgcctgtact accgcttcaa tgagtgaaca aaacaaagtg tttgagcagg
     7501 cttttttcac gatgataaac cagcgccagt tacgccctgg ggaaactttt tctgaactgc
     7561 aactggctcg ggccgcgggt gtcagcccgg ttgtagtaag agaatatctt ttaaaattcg
     7621 gccgttataa tcttattcaa agcgaaaagc gcggccagtg gagcatgaag caattcgatc
     7681 aatcctacgc cgagcagctg tttgaactac gcgaaatgct cgaaacacat tcacttcagc
     7741 actttctcaa cctgcctgat catgatcccc gctggctgca ggcgaaaacc atgctcgaac
     7801 gtcatcggct actgcgtgac aacatcggca atagctttcg catgttctcg caacttgaca
     7861 gagattttca ctccttactg ctttcagctg ccgacaatat cttttttgat caatctcttg
     7921 agatcatctc agtcatcttt cattttcact atcaatggga cgaaagcgat cttaaacagc
     7981 gcaatatcat tgccgtcgat gagcatatga ccattctcag cgctctgatt tgccgcagtg
     8041 accttgatgc cacccttgcg ctccgtaacc atttgaattc agctaaacaa tcaatgattc
     8101 gatccattaa tgagaacacg cgttatgctc attaagtacg gattaaaaac agcaaactat
     8161 tagcggtgca cggttttatc aaaagataaa taccgggaaa ttcccgctta cctatgctca
     8221 caatcagtcg actaaaaatg tttttgtgag cggtagtaaa gtcctaaaac tttaacctgc
     8281 cgttaatgtc aaccttgcgt aatgcacaat tacgtaaaca attaaaatta taaatacagg
     8341 agtccggcgt ggaaaaagaa aatatcaccc tcgatccgcg ttcttcattt actccatctt
     8401 cgtcggcaga tattcccgtg ccaccagatg gattagttca acgcagcacc cgaattaaac
     8461 gcattcaaac caccgccatg ttgttattat tttttgcggc ggtaatcaat tatctcgacc
     8521 gcagttcgct gtcggtagca aatttaacga ttcgtgaaga attgggatta agtgccaccg
     8581 aaatcggcac tttgctctcc gtgttttcac tcgcttacgg gattgcgcaa cttccttgcg
     8641 gcccactatt ggatcgtaaa ggcccgcgcc tgatgctggg actcgggatg ttcttctggt
     8701 cactgttcca ggcaatgtct ggcatggtgc acagctttac gcagttcgtg ttggtgcgta
     8761 tcggtatggg gattggtgaa gcgccgatga acccatgcgg tgtaaaagtc attaacgact
     8821 ggttcaacat caaagagcgc ggacgcccga tgggcttctt caacgcagct tctaccattg
     8881 gcgttgccgt aagcccaccg attctggcgg cgatgatgct ggtgatgggc tggcgtggga
     8941 tgtttattac cattggtgtg ctggggattt ttctcgccat tggctggtat atgctctatc
     9001 gcaaccgcga gcacgtagaa ctgactgccg ttgaacaagc ttacctcaat gctggtagcg
     9061 tgaatgcccg ccgagatccg ctcagttttg ccgaatggcg cagcctgttc cgtaaccgca
     9121 caatgtgggg aatgatgctc ggattcagtg gcatcaacta cactgcgtgg ctgtatctgg
     9181 cctggcttcc tggttacctg caaacagcct ataacctgga tttaaaaagc acagggttga
     9241 tggcggctat ccctttcctg tttggggctg ccgggatgct ggtcaacggt tacgttactg
     9301 actggctggt caaaggggga atggctccga ttaaaagccg taagatctgc attattgccg
     9361 ggatgttctg ttctgccgcc tttacgctgg tcgtaccgca agcgacaaca tccatgacgg
     9421 cggttctgct gattggcacg gcactgttct gtattcactt tgccggaaca tcctgctggg
     9481 gcttgatcca cgtcgcagtt gcttctcgca tgactgcgtc ggtgggcagt atccagaact
     9541 ttgccagctt catctgcgcc tctttcgcgc cgatcattac tggttttatt gttgatacca
     9601 cccattcatt ccgtctggca ctaatcatct gcggttgcgt cactgcggcg ggtgcactgg
     9661 cgtacatctt cctggttcgt cagccgatca acgacccacg gaaagattaa tctccctatg
     9721 cccgataaca ttttgcttat cgggcatttt tatggcgatt aaaacgtttc ccagttctcc
     9781 ccgctatctg ccacggccat tttacgcggc gcagctggcg tcacggtttt taccacagcc
     9841 gatgtttcac gctgctgttg ctgctgttgc tgaatccgga acactgccac agcttcggtc
     9901 aggcgactgg cctgctcttc cagcgcggcg gcggcagcgg cagattcttc caccagcgca
     9961 gcgttctgtt gggttactct gtccatctca gcgaccgcta agccaacctg atcgatacca
    10021 cggctctgct catcagaagc cgaagcaatt tcgcccataa tgtccgtcac gcgggtcacg
    10081 gcactgacaa tctccgccat tgtttcccct gcgctttcga ccagcgtaga gccaacatct
    10141 actttcccca ccgagtcttc aatcaggctt ttaatttcac gagccgcctg agcgctgcgc
    10201 tgggccagat tacgcacttc acccgcgacc accgcaaaac cgcgcccttg ctcacccgcg
    10261 cgcgctgctt caaccgccgc gttcaaagcg agaatattgg tctggaaggc aatgccgtca
    10321 attacgctga taatatcggc gattttctgc gaactggtgg agatatcgcg catggtctgc
    10381 accacgttat ccaccacttt gccgccgcgt tgcgccgttt cagaagcact taacgccagg
    10441 tggctggcct ggcgcgcatt ttcggcgttc tgcttcaccg ttgcggtcag ttgctccatg
    10501 ctggctgccg tctcttccag cgaagcggcc tgttgctcgg tgcgcgaaga gagatcgtta
    10561 ttgccggtag cgatttcgct ggcaccgcta tagatggcat tggccccgtt gcgcacatca
    10621 ccgacggtac gcatcagctc tccctgcata tggcgcaaac tctcagccag ttgccccatc
    10681 tcattagagc catccacctc aatcggtttc accagatcgc cgcctgcaat atgacgaatg
    10741 ctgtcaatca ggcgattcat tggcgctacc aacgaggctt taataccgaa ccagacggcg
    10801 aagatgaccg ccagtacgac gatcatcacg cccaccagaa tccacatcgc ctggctgtag
    10861 gaggcattgt tatcgctgac ggcgatatca tagagccgat cgttttgctc catgtaagcc
    10921 acatactgct tctcgaaacc gtcctgatat ccctgggtcg gctgatcaaa gaactcgttg
    10981 attttgcctg cacctaacag ttggatcagc tccgccagcg cattgtgata aatatcgtaa
    11041 ttacgtttga tctctgccgc tgcggcggtg ctctgacgcg ggtcacgcgg caacgcttcg
    11101 taatccgccc agtttttttc cgcctgtttc agcgaaatac tggcactctg cattagctca
    11161 gcaacggttg aaccgctacc aatattattc tgatccatca tgtagcggat acccgcgcgg
    11221 ttgagggtgt tacgcgtctg caacaacgcg acccagctgc cattcagcgt ggattgctgc
    11281 tggcgaatgg tttgtaaaac agtgaaattt tctttgtcat tctttaaggc attaaagaac
    11341 agaccgcctg atgtcagttg taaaaggcca aaaacggcca aaaccagcag taagctggtc
    11401 acgatcttga tacgttttaa catggtttct ctttccacta gacagataca ctggttgtcg
    11461 gcctggtggt ggaaaacttt atgctgtgga aaagcgtcgg cactgctttt gttgcagcaa
    11521 acttgcgttt tttgtgaggg tcacactcta tagcggcagt ttatggtaca aagtatcaat
    11581 cttcttcgaa ccagtgatac tcctatggct tatagcatcg atatcatctc ctgcattacc
    11641 gaacggttta tggcgttaac cgccactgaa aagcgtatcg cacaatttat tcttgatgac
    11701 gtctctgccg cagtagagtt gccaattgct gagctggcac ggttaacgca aaccagtcag
    11761 gcgtcggtga cgcgttttgc ccgtgcactg gggtgcaaag atgtccgcga gttgaaagtc
    11821 aaactggcgc agtcactggc tgtcgggcag cggtttattc tcgatgtacc ggatcttgac
    11881 ggtgttcagg ggatctacga agcgattatt agcgtgctgg agacgcatcg tcgttcgctg
    11941 gatatgaatg ccatcagcca ggctgtaagc tggttaagtc aggcgcggca aattcttgcg
    12001 ttaggaactg gcggcggttc cactatctgt tcacaggaga ttcagtaccg tttattccgt
    12061 ctggggctac cggtggtcag tcagaatgat gccctgatga tgagaatgat gtgctcggca
    12121 gtcatgccgc aggatgtggt gattgtgctt tcgctgggcg gttatacacc ggaaatcatc
    12181 gaaagtgcgg caatcgcccg tcagtatggc gcgcgtgtta ttgccattac gccagcacaa
    12241 acaccgctgg cggaacaggt ggatctggta ttgccgttac tggttcagga aagtgattac
    12301 atctttaagc ccaccccttc ccgctacgcg atgttagcca tggtcgatgt actggcaaca
    12361 gaactggcaa tggcaaataa agcgcaggcg aaagatcgcc tgcggcggat aaaactcgtg
    12421 ttagacagcc accgtggggg cgctaaccgc cagccacttg gcgattagca ttgtcggtta
    12481 tgcttcttca ggtttggtga tcacgacact ctggttttca cgctcattgg tgataatagc
    12541 caaagcttct tcccggctga cctgacttgc tggcgttacc aacgtcacca gtacgccagc
    12601 gaccaggctg cccagcactg acggaataca cgggttaccc cagtaagcca gccagtcggc
    12661 attcatcagc accacaattg acatcaccat accgctcact aacgccgcca gcgcgccctg
    12721 ccagttaaag cgtagccaga agcgaccgag aatcgagcag ataaacagcc cggacatcag
    12781 catcgaaatc attttggtaa tgtagctgat gatgtcatta gaggtcagag caaagaccag
    12841 cgccaggcca ataacaaagg tcaacatcca gcgtgagtaa gtaatggcct tgtcctccgg
    12901 cggcattctg ccggtaatca tggtgtagac gtcgcgcatc ataatcgcca ccgccgcgat
    12961 ggcatcggag ctggcagaag acatggtggc tgaaagcccg gcaatcagca ccaccagccc
    13021 aagaatggca ggtaagaaac tggtcgcgaa caagaaggcg tagttgctgt tttccagatt
    13081 tgggttcatg gtgaacgccg ccatgccgat aatggcaggc aaaatcgaga agaacagata
    13141 taacacccca gtaataacaa acgaacggcg tacagaggga acatctttac ccgagtaaat
    13201 acgctggcga taagacggtg tggccagtac gccgacacca ataaccagcg ccagcgaaag
    13261 cgcaggtaga acgcccattt tatcaatcgc aaacaggctc atcgcttttg ggtccatcgc
    13321 ctgttcaatc gcactccagc cgccaacgtg aacaacggcg agaatagcca tcaatataaa
    13381 gccaaagaac agaattaagg cctgaatggt gtctgtccac actaccgccg aataaccgcc
    13441 gataataacg taaatcgcaa aagctaaggc gataattaat tttgctacag taagatcaat
    13501 acctgttgcc caggcaagat acatactgcc acctaatata tgcgccccca gccagccaat
    13561 agaggcaata aatatcatca ggccgacaat atttttaatt aaatgactcc cgccagtata
    13621 ataagatatt tcttcactca tggtcataaa acgtaattta cgtaccggtg caaacagcca
    13681 cgccaccagt aatataccta cggccccacc gacgccataa agcattccgg cccagccatt
    13741 gctgtagcca aagcccacgg cgcccatact ggaacccgtg ccaaccatcg tggcaacggt
    13801 tgagcccagc gtcagaaaca gcggcaacga acgcccgccc agcagaaaat cttctccgct
    13861 tttctgatta cgagacacaa accaaccaag ccaaatcatg gcgatggcat aaataataaa
    13921 gccgactaaa aagatatgac tgttcataat tcacatcctg ccagtagaga gagaataaag
    13981 taagagttcc cggagtgctg aatgtattca gcactcaatt gcggtctatt tttttaattc
    14041 ttaaatttat tagcgggtcg cgttataaca ggtcacatcg acttcaactt tacaatcgac
    14101 aaccagatca gctacacaac aaatacgtgc aggcggattc tcgccaaaaa attctctgaa
    14161 tactttatta aatgactgga aatagcgggc gtcggtcagg atcactttca cgtgaaccac
    14221 atccgccagg ctataaccgg cttcagtcat gatgtcgaca cagttttgga tcgccagtcg
    14281 tgactgttca acgataccgc cttctaccac ttcaccgttt ttcatggggg tttgcccgga
    14341 gacgtacagc cagccgcccg cctcaaccgc cctggcaaac ggcaaatgct gcccgccagt
    14401 gcctgttcca ccttccgtac cgtaacgttt aatattcata ttcactcctt aatgtgaggt
    14461 ctggcggcgc aggaagcgtc ccgcacggcc tgtaatgtgt ttatcgcgac catagctcat
    14521 aacgccgttc accatcaccg cctcaatgcc atctgccggg cgtttgggat cagaaaagct
    14581 ggcaacatca cgaatggttt gtggatcgaa caacaccagg tccgcaaaat agccgacttt
    14641 caccagccca cgctgaggca gacgaaaacg gctggcagaa agcccggtca ttttgtggat
    14701 agccgtggtc agtgggaata agccttcatc acggcaatag tgacccagca cgcgagggaa
    14761 agcgccccat aaacgcggat gcggcatggg atcattgggc agtccgtcag agccaatcat
    14821 actgaccgga taactcaaca ctctgcggac gtcgcgctcg tccatgttgt aatagatagc
    14881 cccggcaggc atcagcaact tcgcggcctc cagcatactc atctgccagt cgatggcgat
    14941 ttgtgccagt gttttcccgg cctgctgcgg atgtgtttgt gaccaggtga tcacaatatc
    15001 gaattcgtcg gtgacttgtt tgagatccag cgttgaagaa ctggccgagt aagggtagac
    15061 atcgcagcca atttcctggt gttgacgcat ttggtcaaaa aaggccaacg tttcttttgt
    15121 ccgcccccag tttttcgccc cggcgcattt atggtgggaa accacgacag gcactttgcc
    15181 atgacgccca atacgaaacg cctcatccag ggcatcgaga atcggtttaa attcagaacg
    15241 cagatgggtg gtataaacgc ccttctcacc ggctaattct tccgccagcg ccatgacttc
    15301 ttcggtagtc gcctgaaatg ccgttgcata ggccagcccg gaacttaacc ccagcgcccc
    15361 ctgactcaac gccagacgta agtcggcacg catagcggca atttcatcca ccgtcgccgg
    15421 gcgaaacagg tcgtccatat ggttattacg cagcgccgta tgaccaatca gcgtgccaac
    15481 gttcagtgac ggcctggctg cttccactgc ctgggcatag ctttcaacgg taggataaat
    15541 aaagtgctct gcttccccca acagattcat cgggtcagga acttcacctt tcattttcgc
    15601 cgacgccgca ctgatcccgc agttaccgac aatcaccgta gtgatcccct ggctgatctt
    15661 tggcagatat tccgggatgc gaataacgtt gatatcgtca tgggtatgaa cgtcgataaa
    15721 ccctggtgcc agcacccgcc cttccccgtc aatgacctgc tgcgccgtaa cgttaagcgc
    15781 aggggcaata tcgacaatcc gatcacctgt tattgccacg tcaccgcgaa attcagggcc
    15841 gccgctaccg tcgataacgg tcacattttt gattaaccag tcaacctgca tgttcgtcac
    15901 tccatttctg caatggtgac aagttaacca tttacaagga cgaaaaacag tggaaaacta
    15961 cgcaaaaccc agatgatttt atgatacttt tattcataaa taataagata aataaactaa
    16021 atatttatat ttcatttagt tacaaatgat actcacatcc gatacggtga aaaacttaaa
    16081 aggtaaatgt tatgaaatac cactcagaac ctctggttcc ccataaatct gccctgatgc
    16141 aaatgcccgc aaatctcctt gccgaagatg tctgtttacc tgccgcgatc attaaaaagc
    16201 aggccctgga gaacaacatt acgtggatgc aacgctacgc tgacgcgcgc ggcgtttcac
    16261 tggcaccgca cggtaaaacc accatgacgc cgtggatttt tcaggcgcag caggcggctg
    16321 gtgcctgggc aataggtgtc ggtagcgcat ggcaggctgg tgcggcaatg gcgagcggta
    16381 ttcagcgagt gctgatggtt aaccagctgg tcggcaaggc gaatatgcag ttgattgccc
    16441 agttgcaaca acattacccg acggtcgatt ttatctgctg tatcgacagc attgagaacg
    16501 cccgcgcttt gtctgccttt tttgccagtc agcaacagac actgaacgtg atgattgaac
    16561 tgggtgttcc cggcgggcgc tgtggttgcc gctcaacgga tgccgcactg gcactggcta
    16621 aacaggcagc ccaattaccg gggttacgcc tgcgggggct tgagttatat gaaggcgttt
    16681 tacacggtga cgatccacaa ccgcaggtag aagctctgct gcgggatgcc gcacaactgg
    16741 cctgtgatat ggcaaatctg gttgatggcg agtttattct caccggagca ggcacggtct
    16801 ggtatgacgt ggtgtgcaat atctggctgg cggcagaaaa gcctgataac tgccgcattg
    16861 ttattcgccc tggctgctac atcactcacg acaccgggat ctacgacgcg gcacaacaac
    16921 agttgcttgc ccgtgatcct gtggcctgcg atctggcagg cgatctcaca tctgcgctgg
    16981 aactggtcgc catggtgcaa tcggtgccgg aagctgatcg tgcggtggta aattttggta
    17041 agcgtgattg cgccttcgac gccggactgc cgcaaccagt cgcccactac cgcaacggca
    17101 aatcactggc atttgatcca caggcgattc gcagtacagg tattatggat cagcactgca
    17161 tgttgcaact gtcagctaat agcgacgtgc aagtggggga tattctggtg tttggcacat
    17221 cgcatccgtg cctgaccttc gacaaatgga aaacgttgtt attggctgat gacgactaca
    17281 acgtactggc ggaattagac actctcttct aagaataccc cttcggttaa ttatcgaagg
    17341 ggcattttta ttgtgatctc aatcacatat ccacccgacg aataattctt gcccaaccgc
    17401 tcaccgccat tcctgaccgc ttacgtccca aatataacca ctcagttatt taccttactt
    17461 tacgcgcgcg taactctggc aacatcactg caggatagcg gtcaatttac ctcctcaaac
    17521 gcaacgcaaa cctagaacgg cttcggccaa ctattaatca atacatgcca ggttttacta
    17581 tggatactaa aaagatattc aagcacatac cctgggtgat tcttggaatc atcggtgcat
    17641 tctgcctcgc ggtagttgca ttacgtcggg gggagcacgt cagtgccctg tggatcgtgg
    17701 tcgcctctgt gtcggtgtat ctggtggctt atcgctacta cagtctgtac atcgcccaga
    17761 aggtaatgaa actcgacccc acgcgcgcga cgcctgcggt tattaacaac gacggtctga
    17821 actatgttcc gaccaaccgt tacgtgttgt ttggtcacca cttcgccgct atcgccggtg
    17881 cgggtccgct ggttggtccg gttctcgccg cacagatggg ttacctgcct ggtacgctgt
    17941 ggctgctggc gggggtagtg ctggccggtg cggtacagga ctttatggtg ctgtttatct
    18001 cctctcgccg taacggtgca tctctcggtg agatgatcaa agaagagatg gggccagtac
    18061 cggggactat cgcgctgttt ggctgtttct taatcatgat catcatcctc gccgttctgg
    18121 cgctgattgt ggttaaagcc ctggccgaaa gtccgtgggg ggtcttcacc gtttgctcaa
    18181 ccgtaccgat tgcgctgttt atgggtatct acatgcgctt tatccgtccg gggcgtgtag
    18241 gtgaagtctc tgttattggt atcgtgctgc tggttgcctc tatctacttc ggtggcgtaa
    18301 ttgctcacga tccgtactgg ggtccggcac tgacctttaa agacaccacc attaccttcg
    18361 cgctgattgg ctatgcgttt gtttccgcac tgttgccggt gtggctgatc ctcgcaccgc
    18421 gcgactatct ggcaaccttc ctgaaaatcg gcgttatcgt cggcctggca ctgggtatcg
    18481 tggtgctgaa cccggaactg aaaatgcctg cgatgacgca gtacattgac ggtactggcc
    18541 cgctgtggaa aggcgctctg ttcccgttcc tgttcatcac catcgcctgt ggtgcggtat
    18601 ctggcttcca cgcgctgatc tcttccggta cgacgccgaa actgctggct aacgaaaccg
    18661 acgcgcgttt cattggctac ggcgcaatgc tgatggagtc cttcgtggcg attatggcgc
    18721 tggttgctgc atccatcatc gaaccgggtc tttacttcgc gatgaatacc ccgcctgcgg
    18781 gccttggcat caccatgcct aacctgcatg aaatgggtgg cgagaacgcg ccgatcatca
    18841 tggcgcagct gaaagacgtt accgcacacg cggcagcgac tgtcagctcc tggggcttcg
    18901 tgatttcgcc agagcagatc ctgcaaaccg cgaaagacat tggtgagcct tctgtcctga
    18961 accgtgcagg tggtgcgccg acgctggcgg taggtatcgc tcacgtgttc cacaaagtgc
    19021 tgccgatggc tgacatgggc ttctggtatc acttcggtat tctgttcgaa gccctgttca
    19081 tcctgaccgc gctggatgcg ggtacccgtt ctggccgctt tatgctgcaa gacctgctgg
    19141 gtaacttcat cccgttcctg aaaaaaaccg attctctggt tgccggtatc atcggtactg
    19201 cgggctgtgt gggtctgtgg ggctacctgc tgtatcaggg cgtggttgat ccgctgggcg
    19261 gcgttaagag cctgtggccg ctgttcggta tctccaacca gatgctggca gccgtagcgc
    19321 tggtactggg caccgttgtg ctgattaaga tgaagcgcac ccaatacatc tgggtaactg
    19381 ttgttccggc tgtatggctg cttatctgca ccacctgggc gctgggcctg aaactgttca
    19441 gcaccaaccc gcagatggaa ggcttcttct acatggcaag ccagtacaaa gagaagattg
    19501 ctaacggtac tgacctgacg gcgcagcaga ttgccaacat gaaccacatc gttgtgaaca
    19561 actacactaa cgcgggtctg agtattctgt tcctgattgt ggtgtacagc atcatcttct
    19621 acggtttcaa aacctggctg aaggtgcgaa acagcgacaa acgtactgac aaagaaacac
    19681 cgtacgttcc aatcccggaa ggcggcgtga agatctcttc gcaccactaa ccggttgccg
    19741 gatgcgctgc gcgtatccgg cctacaaagt gtctatcgta ggccggataa ggcgtttacg
    19801 ccgcatccgg caaatccccg gcccggacct tccgggcttt acgcatatct ggaaggcaaa
    19861 atgtttggta acttaggaca ggcaaaaaaa tatctcggcc aggcggcgaa gatgttgatt
    19921 ggcattccag actacgacaa ctacgtcgag catatgaaga ccaaccatcc cgacaagccg
    19981 tacatgagct atgaagaatt cttccgcgaa cgccagaacg cgcgctacgg cggcgatggt
    20041 aaaggcggta tgcgctgttg ttaatggaga gagcatgaac ccgattgcag ttaccctact
    20101 caccggtttt ttaggcgcag gcaaaaccac cctgctgcgc catattctta atgaacagca
    20161 cggctacaaa attgccgtga ttgaaaacga attcggcgaa gtctctgttg atgatcaact
    20221 gattggcgac cgcgccacgc agatcaaaac gctgaccaac ggctgcatct gttgttcgcg
    20281 ctccaacgag ctggaggacg cgctactcga cctgctggac aatctcgaca agggcaatat
    20341 tcagttcgac cgtctggtca ttgaatgcac cggcatggcc gatcccggcc cgattattca
    20401 gacctttttc tcccatgaag ttttatgcca gcgttatctg ctggacggcg tgattgcgct
    20461 ggtggatgcg gtacatgccg atgagcagat gaaccagttc accatcgccc agtcacaggt
    20521 tggctacgcc gaccgcattc tgctgaccaa aaccgacgtc gcaggcgaag cagaaaaact
    20581 gcatgaacgc ctggcgcgca tcaacgcccg cgcaccggtc tacaccgtca cccacggcga
    20641 catcgatctg ggcctgctgt tcaacaccaa cggttttatg ctggaagaaa acgtcgtcag
    20701 caccaaaccg cgtttccact ttatcgcaga taaacaaaac gatatttcgt cgattgtggt
    20761 ggaactggat tacccggtag atatcagcga agtttcccgc gtgatggaaa acctgctgct
    20821 ggagtcggcg gataaactgc tacgttacaa agggatgctg tggattgacg gcgaacctaa
    20881 ccgcctgctg ttccagggcg tccagcgcct ctacagcgcc gactgggaca ggccgtgggg
    20941 cgatgaaaaa ccgcatagca cgatggtgtt tatcgggatc cagctgccgg aggaagagat
    21001 tcgggctgcg tttgcggggt tgaggaagta aggggttatg ggccggataa ggcgcagccg
    21061 catccggcct gatatttcac tcaaaatagt ccatatccag tttcggcacc ttcaacaaac
    21121 gtgaagaaac ccctacttcg ttttcgatca ttaagtgcac caggcgttcc ccatcaacca
    21181 acaccatacc ctcgacggat tgggcaaagt cacgcgcctg agaagtaaat ccagaagtgg
    21241 taataaacac cccacgtttc gctttttgcc cagccagtgc gccgtaaaat gcctgtaatt
    21301 ctggcctgcc tacagtattc tgccaacgtt ttgcctgaac ataaactttc tccaggccaa
    21361 gtttatcaag cgatatcaca ccatcgatgc caccatctcc agtaccgcca acacgctgca
    21421 aatcatcacg gtggccgcca taccccaggc gatgcaaaac atccagaaca atgacttcaa
    21481 agcgcgaagg agaaacctgc aataagtttt ccagaacctc atcagccacc gcatcacgaa
    21541 gctcttttag cgcctgatct aaccgatcgt ccgggctgct ctttgcaagt tcttcatgat
    21601 cgggagagtc ggctttcgga tctaaatcga cggcatccgg ccgtgactta agtttgacat
    21661 tcacaaaagc gaaggccaga tggttcgtct cctgctccgt cattggctgg ggatgagacg
    21721 caacccagtc aaaacccgca ggagtcaggc accatttgcc acgcgacaaa ctttgcgaca
    21781 acccggcacg ttttaaacgg tcatgcgccc agcctgcacg atttttataa acaagttgtc
    21841 cgctggtaat gactttcgct cgctggctgt catccagtcc taatgcatcc gcggcagcct
    21901 catgaacatc acgcgcggct gcaccttccg gttttgttgc cagataacgc agaacaggtt
    21961 caataaattt gtcataggta ggaaccgtca tagtacatcc ttgcagaatc aggtagatgt
    22021 ttttcggcta ctatagcact acaaaaatag acgaacacgt tagaaatgag tcagttgctg
    22081 tgaccgtggt cattgcccgg aaaggtacag aaagctaaga tgagatgtta tgggccttaa
    22141 atatttggac aggcccgcac agcaatggat taataacaat gatgaataaa tccaattttg
    22201 aattcctgaa gggcgtcaac gacttcactt atgccatcgc ctgtgcggcg gaaaataact
    22261 acccggatga tcccaacacg acgctgatta aaatgcgtat gtttggcgaa gccacagcga
    22321 aacatcttgg tctgttactc aacatccccc cttgtgagaa tcaacacgat ctcctgcgtg
    22381 aactcggcaa aatcgccttt gttgatgaca acatcctctc tgtatttcac aaattacgcc
    22441 gcattggtaa ccaggcggtg cacgaatatc ataacgatct caacgatgcc cagatgtgcc
    22501 tgcgactcgg gttccgcctg gctgtctggt actaccgtct ggtcactaaa gattatgact
    22561 tcccggtgcc ggtgtttgtg ttgccggaac gtggtgaaaa cctctatcac caggaagtgc
    22621 tgacgctaaa acaacagctt gaacagcagg tgcgagaaaa agcgcagact caggcagaag
    22681 tcgaagcgca acagcagaag ctggttgccc tgaacggcta tatcgccatt ctggaaggca
    22741 aacagcagga aaccgaagcg caaacccagg ctcgccttgc ggcactggaa gcacagctcg
    22801 ccgagaagaa cgcggaactg gcaaaacaga ccgaacagga acgtaaggct taccacaaag
    22861 aaattaccga tcaggccatc aagcgcacac tcaaccttag cgaagaagag agtcgcttcc
    22921 tgattgatgc gcaactgcgt aaagcaggct ggcaggccga cagcaaaacc ctgcgcttct
    22981 ccaaaggcgc acgtccggaa cccggcgtca ataaagccat tgccgaatgg ccgaccggaa
    23041 aagatgaaac gggtaatcag ggctttgcgg attatgtgct gtttgtcggc ctcaaaccca
    23101 tcgcggtggt agaggcgaaa cgtaacaata tcgacgttcc cgccaggctc aatgagtcgt
    23161 atcgctacag taaatgtttc gataatggct tcctgcggga aaccttgctt gagcactact
    23221 caccggatga agtgcatgaa gcagtgccag agtatgaaac cagctggcag gacaccagcg
    23281 gcaaacaacg gtttaaaatc cccttctgct actcgaccaa cgggcgcgaa taccgcgcaa
    23341 caatgaagac caaaagcggc atctggtatc gcgacgtgcg tgatacccgc aatatgtcga
    23401 aagccttacc cgagtggcac cgcccggaag agctgctgga aatgctcggc agcgaaccgc
    23461 aaaaacagaa tcagtggttt gccgataacc ctggcatgag cgagctgggc ctgcgttatt
    23521 atcaggaaga tgccgtccgc gcggttgaaa aggcaatcgt caaggggcaa caagagatcc
    23581 tgctggcgat ggcgaccggt accggtaaaa cccgtacggc aatcgccatg atgttccgcc
    23641 tgatccagtc ccagcgtttt aaacgcattc tcttccttgt cgaccgccgt tctcttggcg
    23701 aacaggcgct gggcgcgttt gaagatacgc gtattaacgg cgacaccttc aacagcattt
    23761 tcgacattaa agggctgacg gataaattcc cggaagacag caccaaaatt cacgttgcca
    23821 ccgtacagtc gctggtgaaa cgcaccctgc aatcagatga accgatgccg gtggcccgtt
    23881 acgactgtat cgtcgttgac gaagcgcatc gcggctatat tctcgataaa gagcagaccg
    23941 aaggcgaact gcagttccgc agccagctgg attacgtctc tgcctaccgt cgcattctcg
    24001 atcacttcga tgcggtaaaa atcgctctca ccgccacccc ggcgctacat actgtgcaga
    24061 ttttcggcga gccggtttac cgttatacct accgtaccgc ggttatcgac ggttttctga
    24121 tcgaccagga tccgcctatt cagatcatca cccgcaacgc gcaggagggg gtttatctct
    24181 ccaaaggcga gcaggtagag cgcatcagcc cgcagggaga agtgatcaat gacaccctgg
    24241 aagacgatca ggattttgaa gtcgccgact ttaaccgtgg cctggtgatc ccggcgttta
    24301 accgcgccgt ctgtaacgaa ctcaccaatt atcttgaccc gaccggatcg caaaaaacgc
    24361 tggtcttctg cgtcaccaat gcccatgccg atatggtggt ggaagagctg cgtgccgcgt
    24421 tcaagaaaaa gtatccgcaa ctggagcacg acgcgatcat caagatcacc ggtgatgccg
    24481 ataaagacgc gcgcaaagtg cagaccatga tcacccgctt caataaagag cggctgccca
    24541 atatcgtggt aaccgtcgac ctgctgacga ccggcgtcga tattccgtcg atctgtaata
    24601 tcgtgttcct gcgtaaagta cgcagccgca ttctgtacga acagatgaaa ggccgcgcca
    24661 cgcgcttatg cccggaggtg aataaaacca gctttaagat ttttgactgt gtcgatatct
    24721 acagcacgct ggagagcgtc gacaccatgc gtccggtggt ggtgcgcccg aaggtggaac
    24781 tgcaaacgct ggtcaatgaa attaccgatt cagaaaccta taaaatcacc gaagcggatg
    24841 gccgcagttt tgccgagcac agccatgaac aactggtggc gaagctccag cgtatcatcg
    24901 gtctggccac gtttaaccgt gaccgcagcg aaacgataga taaacaggtg cgtcgtctgg
    24961 atgagctatg ccaggacgcg gcgggcgtga actttaacgg cttcgcctcg cgcctgcggg
    25021 aaaaagggcc gcactggagc gccgaagtct ttaacaaact gcctggcttt atcgcccgtc
    25081 tggaaaagct gaaaacggac atcaacaacc tgaatgatgc gccgatcttc ctcgatatcg
    25141 acgatgaagt ggtgagtgta aaatcgctgt acggtgatta cgacacgccg caggatttcc
    25201 tcgaagcctt tgactcgctg gtgcaacgtt ccccgaacgc gcaaccggca ttgcaggcag
    25261 ttattaatcg cccgcgcgat ctcacccgta aagggctggt cgagctacag gagtggtttg
    25321 accgccagca ctttgaggaa tcttccctgc gcaaagcatg gaaagagacg cgcaatgaag
    25381 atatcgccgc ccggctgatt ggtcatattc gccgcgctgc ggtgggcgat gcgctgaaac
    25441 cgtttgagga acgtgtcgat cacgcgctga cgcgcattaa gggcgaaaac gactggagca
    25501 gcgagcaatt aagctggctc gatcgtttag cgcaggcgct gaaagagaaa gtggtgctcg
    25561 acgacgatgt cttcaaaacc ggcaacttcc accgtcgcgg cgggaaggcg atgctgcaaa
    25621 gaacctttga cgataatctc gataccctgc tgggcaaatt cagcgattat atctgggacg
    25681 agctggcctg acacgtatac acttcatcct tcaggctgcc tctgcgttgg ctgcgctcgt
    25741 tcaccccggt cacgtacttc tgtacgctcc cggggattca ctcacttgcc gccttgatgc
    25801 aacctgaatg attttgtgta tattaccctc ggcaatttct tcttctgcgg ctcgatgaat
    25861 ttgggccgct gcttaattta cggaactcac aatgaacaat aacgatctgg tcgcgaagct
    25921 gtggaagctg tgcgacaacc tgcgcgatgg cggcgtttcc tatcaaaact acgtcaatga
    25981 actcgcctcg ctgctgtttt tgaaaatgtg taaagagacc ggtcaggaag cggaatacct
    26041 gccggaaggt taccgctggg atgacctgaa atcccgcatc ggccaggagc agttgcagtt
    26101 ctaccgaaaa atgctcgtgc atttaggcga agatgacaaa aagctggtac aggcagtttt
    26161 tcataatgtt agtaccacca tcaccgagcc gaaacaaata accgcactgg tcagcaatat
    26221 ggattcgctg gactggtaca acggcgcgca cggtaagtcg cgcgatgact tcggcgatat
    26281 gtacgaaggg ctgttgcaga agaacgcgaa tgaaaccaag tctggtgcag gccagtactt
    26341 caccccgcgt ccgctgatta aaaccattat tcatctgctg aaaccgcagc cgcgtgaagt
    26401 ggtgcaggac ccggcggcag gtacggcggg ctttttgatt gaagccgacc gctatgttaa
    26461 gtcgcaaacc aatgatctgg acgaccttga tggcgacacg caggatttcc agatccaccg
    26521 cgcgtttatc ggcctcgaac tggtgcccgg cacccgtcgt ctggcactga tgaactgcct
    26581 gctgcacgat attgaaggca acctcgacca cggcggcgca atccgtctgg gcaacactct
    26641 gggtagcgac ggtgaaaacc tgccgaaggc gcatattgtc gccactaacc cgccgtttgg
    26701 cagcgccgca ggcaccaaca ttacccgcac ctttgttcac ccgaccagca acaaacagtt
    26761 gtgctttatg cagcatatta tcgaaacgct gcatcccggc ggtcgtgcgg cggtggtggt
    26821 gccggataac gtgctgtttg aaggcggcaa aggcaccgac attcgtcgtg acctgatgga
    26881 taagtgtcat ctgcacacca ttctgcgtct gccgaccggt attttttacg ctcagggcgt
    26941 gaagaccaac gtgctgttct ttaccaaagg gacggtggcg aacccgaatc aggataagaa
    27001 ctgtaccgat gatgtgtggg tgtatgacct gcgtaccaat atgccgagtt tcggcaagcg
    27061 cacaccgttt accgacgagc atttgcagcc gtttgagcgc gtgtatggcg aagacccgca
    27121 cggtttaagc ccgcgcactg aaggtgaatg gagttttaac gccgaagaga cggaagttgc
    27181 cgacagcgaa gagaacaaaa acaccgacca gcatcttgct accagccgct ggcgcaagtt
    27241 cagccgtgag tggatccgca ccgcaaaatc cgattcgctg gatatctcct ggctgaaaga
    27301 taaagacagt attgatgccg acagcctgcc ggagccggat gtattagcgg cagaagcgat
    27361 gggcgaactg gtacaggcgc tgtctgaact ggatgcgctg atgcgtgaac tgggggcgag
    27421 cgatgaggcc gatttgcagc gtcagttgct ggaagaagcg tttggtgggg tgaaggaatg
    27481 agtgcgggga aattgccgga ggggtgggtt atcgccccag tatctacggt cacaactcta
    27541 atccgaggag taacgtataa aaaagagcag gcaataaatt atctaaaaga tgattatttg
    27601 cctcttatcc gtgcgaacaa tattcagaat ggcaagtttg atactacgga cttggttttt
    27661 gttcctaaaa atcttgttaa agaaagtcaa aaaatatctc ctgaagatat tgttattgca
    27721 atgtcatcag ggagcaaatc cgtagttggt aaatccgcac atcagcatct accatttgaa
    27781 tgtagtttcg gcgcattttg cggtgtatta cgtcctgaaa aacttatatt ttctggtttt
    27841 attgctcatt tcacaaaatc ttctctttat cgaaacaaaa tttcatcact ttctgctggt
    27901 gcaaatatta ataatattaa gccggcaagc tttgatttga taaatatacc aatcccacca
    27961 cttgccgaac aaaaaatcat cgctgaaaaa ctcgatacgc tgctggcgca ggtagacagc
    28021 accaaagcac gttttgagca aatcccacaa atcctgaaac gttttcgtca agcggtattg
    28081 gggggcgcag ttaatggaaa attgacagaa aaatggcgta attttgagcc gcaacattct
    28141 gtatttaaga agttaaattt tgaatctatc ttaactgaat tacgtaatgg tctttcatca
    28201 aagccaaatg aaagtggtgt tggtcatcca atactacgca ttagttctgt acgtgctggc
    28261 catgtagatc aaaacgatat tcggtttcta gaatgttcag aaagtgaact aaaccgccac
    28321 aaattacaag atggagatct tttatttact cgctataacg gaagtttaga atttgttggt
    28381 gtttgtgggt tattgaaaaa attacaacat caaaatttgc tatatcctga taaacttatt
    28441 cgagctcgat taaccaaaga tgctttacca gaatatatcg aaatattttt ttcatccccc
    28501 tcagcacgaa atgcaatgat gaactgcgtg aaaacaactt ctggtcaaaa aggtatttca
    28561 ggaaaagata tcaaatccca agttgtttta ttacctccag taaaagaaca agccgaaatc
    28621 gttcgccgcg tcgagcaact cttcgcctac gccgacacca tagaaaaaca ggtcaacaac
    28681 gccttagccc gcgtcaacaa cctgacgcaa tccatcctgg caaaagcgtt ccgtggtgaa
    28741 cttaccgccc agtggcgggc cgaaaacccg gatttgatca gcggagaaaa cagcgccgcc
    28801 gcgttgctgg aaaaaatcaa agctgaacgc gcagctagcg ggggtaaaaa agcctcacgt
    28861 aaaaaatcct gaacattatt ttctggcgca cctttccggt gcgcttttta ttatttcacg
    28921 ccaatcataa cccacataaa tatatttaaa tcattccaga aattgcccat tttattctat
    28981 ttttagctgg actttcccca tatttactga tgatatatac aggtatttag cgcggtgcgg
    29041 atgtgcgcca acacacccgc atcgctaatc acaatcacta ttcctggaga atagcagtta
    29101 tgactgacac gcattctatt gcacaaccgt tcgaagcaga agtctccccg gcaaataacc
    29161 gtcatgtcac cgtcggttat gcgagtcgct acccggatta cagccgtatt cccgccatca
    29221 ccctgaaagg tcagtggctg gaagccgccg gttttgccac tggcacggcg gtagatgtca
    29281 aagtgatgga aggctgtatt gtcctcaccg cccaaccacc cgccgccgag gagagcgaac
    29341 tgatgcagtc gctacgccag gtgtgcaaac tgtcggcgcg taaacaaaag caggtgcagg
    29401 cgtttattgg agtgattgcc ggtaaacaga aagtcgcgta acagcgttta ctcccggtta
    29461 accaccggga gccttccact gactcaatag aaactttccc cctcagtaaa tatttaccag
    29521 tctgattttg cagtaaaaat ctattgtttc agtacgttgc gaaagcgata atagaggctt
    29581 agcaatgagg aaggcatatc ttatggaatc tattcaaccc tggattgaaa aatttattaa
    29641 gcaagcacag caacaacgtt cgcaatccac taaagattat ccaacgtctt accgtaacct
    29701 gcgataaaat tgagtttcgg ttatggtaat tttacgtcta ttccctggtt tgcatttctt
    29761 ggagaaggtc aggaagcttc taacggtata tatcccgtta ttctctatta taaagatttt
    29821 gatgagttgg ttttggctta tggtataagc gacacgaatg aaccacatgc ccaatggcag
    29881 ttctcttcag acatacctaa aacaatcgca gagtattttc aggcaacttc gggtgtatat
    29941 cctaaaaaat acggacagtc ctattacgcc tgttcccaaa aagtctcaca gggtattgat
    30001 tacacccgat ttgcctctat gctggacaac ataatcaacg actataaatt aatatttaat
    30061 tctggcaaga gtgttattcc acctatgtca aaaactgaat catactgtct ggaagatgcg
    30121 ttaaatgatt tgtttatccc tgaaaccaca atagagacga tactcaaacg attaaccatc
    30181 aaaaaaaata ttatcctcca ggggccgccc ggcgttggaa aaacctttgt tgcacgccgt
    30241 ctggcttact tgctgacagg agaaaaggct ccgcaacgcg tcaatatggt tcagttccat
    30301 caatcttata gctatgagga ttttatacag ggctatcgtc cgaatggcgt cggcttccga
    30361 cgtaaagacg gcatatttta caatttttgt cagcaagcta aagagcagcc agagaaaaag
    30421 tatattttta ttatagatga aatcaatcgt gccaatctca gtaaagtatt tggcgaagtg
    30481 atgatgttaa tggaacatga taaacgaggt gaaaactggt ctgttcccct aacctactcc
    30541 gaaaacgatg aagaacgatt ctatgtcccg gagaatgttt atatcatcgg tttaatgaat
    30601 actgccgatc gctctctggc cgttgttgac tatgccctac gcagacgatt ttctttcata
    30661 gatattgagc caggttttga tacaccacag ttccggaatt ttttactgaa taaaaaagca
    30721 gaaccttcat ttgttgagtc tttatgccaa aaaatgaacg agttgaacca ggaaatcagc
    30781 aaagaggcca ctatccttgg gaaaggattc cgcattgggc atagttactt ctgctgtggg
    30841 ttggaagatg gcacctctcc ggatacgcaa tggcttaatg aaattgtgat gacggatatc
    30901 gcccctttac tcgaagaata tttctttgat gacccctata aacaacagaa atggaccaac
    30961 aaattattag gggactcata gtggaacagc ccgtgatacc tgtccgtaat atctattaca
    31021 tgcttaccta tgcatggggt tatttacagg aaattaagca ggcaaacctt gaagccatac
    31081 ccggtaacaa tcttcttgat atcctggggt atgtattaaa taaaggggtt ttacagcttt
    31141 cacgccgagg gcttgagctt gattacaatc ctaataccga gatcattcct ggcatcaaag
    31201 ggcgaataga gtttgctaaa acaatacgcg gcttccatct taatcatggg aaaaccgtca
    31261 gtacttttga tatgcttaat gaagacacgc tggctaaccg aattataaaa agcacattag
    31321 ccatattaat taagcatgaa aagttaaatt caactatcag agatgaagct cgttcacttt
    31381 atagaaaatt accgggcatt agcactcttc atttaactcc gcagcatttc agctatctga
    31441 atggcggaaa aaatacgcgt tattataaat tcgttatcag tgtctgcaaa ttcatcgtca
    31501 ataattctat tccaggtcaa aacaaaggac actaccgttt ctatgatttt gaaagaaacg
    31561 aaaaagagat gtcattactt tatcaaaagt ttctttatga attttgccgt cgtgaattaa
    31621 cgtctgcaaa cacaacccgc tcttatttaa aatgggatgc atcgagtata tcggatcagt
    31681 cacttaattt gttacctcga atggaaactg acatcaccat tcgctcatca gaaaaaatac
    31741 ttatcgttga cgccaaatac tataagagca ttttttcacg acgaatggga acagaaaaat
    31801 ttcattcgca aaatctttat caactgatga attacttatg gtcgttaaag cctgaaaatg
    31861 gcgaaaacat aggggggtta ttaatatatc cccacgtaga taccgcagtg aaacatcgtt
    31921 ataaaattaa tggcttcgat attggcttgt gtaccgtcaa tttaggtcag gaatggccgt
    31981 gtatacatca agaattactc gacattttcg atgaatatct caaataagcg gtaagtttta
    32041 tagaaaatac cgctcccgac accacatcgg gagcggctca tcatcaggag gcgatcacct
    32101 ccaccagcac atccgttgcc caactctctt cgctgttggc gacattccct tccttgcagg
    32161 cctgagccat tttgactaac tggaaagaaa cgtcatcgcg gaaatcaaag taatgccatt
    32221 gcgatgaaaa gttgatgcgc cagtagccca tcccctgatc gaagcggatc ttcaatacct
    32281 gaccatcctc aaaagtcacc gtcagtttac gatggtgagg gatatcgcgc ggcgagtcga
    32341 acaccgtcag ttctaccggc ctgcccagcg cagcagcaaa ccactgatca gcgaaatcct
    32401 gaaaatccgc tatgctcatc cagtcatgga aaggccggtt accggggcga tctttatctt
    32461 taaatagcgt atccagcgtc acttcagcgc catcggtcag ctttgttttt agcggtctca
    32521 gaattgatcc caacaacgcc agcgcaaccg ggttttgcag atagcgatcg gtatagtgaa
    32581 cgccggtaat tcgcgtgtta ttcatcagtg actgcgcttc ttcatggtcg ttaaacagca
    32641 cgtcccagaa gcgttgccca aactgcgaca gtggtccatt caactgtttg tggatctgaa
    32701 tgtctttgac ccgctcgaca gcgttggtgg ctttagccgg cagaataaac tcgttcagtt
    32761 ctaccgtttt ataaccgaga ctacgcacca ccagttcgtc attcaggtgc cactccggcc
    32821 ccggaatcgt tgcctgctgg ctgcgagagg ccagcgtcat cacgcgatcg gtaaaggtga
    32881 cctgggcaac gatcggtaat tgcagatcct gttcaacatg gcacagccgc acacccagcg
    32941 cagtaaattg cgatagttca tgcaacaggt ccgggtcatc cactcccgta ggaataacaa
    33001 gatcgacctc gacgttgtct tttagccgat agttctgaac cgccgcgcgg aactgacgtg
    33061 cgtataaatc ccactcattg ggcgcgccgg tcatccacag ggtgagcttt tcagcgcctt
    33121 cgttaatcgc ccggcgaatc gtatcgccaa tggcgccagg gcagtagcgg gcatccggca
    33181 gcgagaatgt ctcttcatcc ggtaaaccga tgtaatacgt gaagtcatcg ccaagccagg
    33241 ccagcgccgc tttgcgatcc agcaaatcgt gatcgtggcg agtctgggaa tcaagcaggc
    33301 attcactaca tgcagtctca caatggcggc agcctaactg tttcaccatt ccctgcaata
    33361 tagcttcaat gtgtaccggt gcgctggagg caaaacctgc accaccgctg atcacatcat
    33421 aaagctgtac ggctaatacc gattgcccat cctccagtct gaccggacgt acagaatagc
    33481 cgagttctgc ggcggagata cccagaacgc ccgccagcgc ctgacgcaga gcaaccgcca
    33541 gagtcatggc aacaatccgc ccctcctctg tgttatctgg cagatactcg ccgttttgcg
    33601 gtttgcgcag aaccatttca aagacatcgg tacgcgccag tgcgcccagg gtgacattct
    33661 tcatgagtgc cgtcgaaccg gggcaaatca gacgatgatt ctggctgtcg cgatccgctt
    33721 tacccggacg cggtggatag tgagcttcca tacttttcgg cgcatcattt tcattcagca
    33781 tcgactcagc acggccacag ctcagacaca atgcataacc gtgtccacct tcccccaaac
    33841 tttgctggaa aacatgccca tcagccccag aagccatata acccattagc gggttaggca
    33901 acggtacggg ctctgcttta acaaagaccc acgcggggac aaccgggacg aatttcatgg
    33961 tttcaatatt gttcgttacc ggagcgtgtg catcggtgac aaacccggca ggctgcagca
    34021 cctgacggcg attatccatg attatttttt cgccgcaggc gctattggag caaaagagca
    34081 tcccggaact gctcatcccc tcttcatagc caatggtccc gcatttgtga cagcgccagg
    34141 cgcaatccag acgctgggct tcattggtat cagcattaat gttgtgccag tgcagtgaga
    34201 caccggcaga gcggaagaca cggccatcaa ggatgatctc tgctcccggt gcatattcac
    34261 gaatggcaac accgaggtta cgggaaggta atcctttata acgggaaacg ttatcttcac
    34321 ggtccttttt atcacgactt ttctgcgatt tttcgcggat ataatcttcc atcgtgaagt
    34381 tatcaaacgt cactacatct gtcgggaaac cgtatcccgg caggaaggtt ctggcagcca
    34441 gatcgcgcag cagatactcg ccacagtgcc gtttcttctc cagctctatg cgcttacgat
    34501 aaggcgtttg cggctgcgac tcacgctcct gtgtcacgag atcgcgataa acggagagcc
    34561 accgctgttg caggaaggtg atcgcgttga ttgttttatc ccgcagatat tcggctcttg
    34621 caccatgcaa cgccgtacct ttcaccagcc gttccagcgc cgtgtcgata tcaagaaccg
    34681 gacgttccag ccagatttta aagcgttcgc attttgactg cccgtcatct tcaccgaaaa
    34741 accagaggct atcgaggctg gttttttctt tatcggtttc gccaataacg ttacataaaa
    34801 agtcggacag taataatgca ttgacgtgac gttgcaccag tcgggcggag ttcatcgcga
    34861 ccatgggtgc cgggatcatg gtttcaaatg gccagagcgg gttggcaaaa acctgctggt
    34921 cgtgtgggtt acctttacat agggtgtaag agatcgcgcg tgattcttta ctacgcccgg
    34981 ctcgcccggc gcgctgtaaa tagttggccg gatgtggcgg tacgttgttc attaccaccg
    35041 cagtaatacc cccgatatca acccccattt ccatggtggt ggaacagttg agaacattta
    35101 gttgcccatt cttgaacatc ttttcatagc tttgcagacg ttctgacgac tgctgggcag
    35161 agtgctcggc agtacgatag tagaagccgc cttccacgac acgatcgtta atgtctgtcc
    35221 agacgttttc cgaccgcaat tgtgcgatca gcggatcatg gctgacccag tcgcgtgctt
    35281 ttgccagacc ctctgcgtag tcttcctgtg aacgatccag cttccagatt tccggcattg
    35341 tgactttctg cgcgacaaaa gtgtcatatt gcgccagggt aagatgctcg aacgaaatat
    35401 gggtaggcag ataaggggtt aagcctttaa aagccgtatc caggatttta ttggttaccg
    35461 ggcaaatcca ggcatccgtg attaaagaaa aagtcatatg ctctttcggt aaataaaaac
    35521 ggttgccatc gggtttcagt actgcaagcg gtccggtaag ttgggcccat gcttctttca
    35581 gccatgtatt gataatatca atagttgccg cattgacggt tttgaatcca gcccccagca
    35641 tcagcaactt cgctaaacga tgggatacgt tgccattacg aatttgaggc cagcgtctgt
    35701 tctgattatc ttcaggatct tttgattccg ggttacggac gaattttgat gaaaaacggc
    35761 taccaatcca gtttttcagc tcatcatcca gctgtgtgaa gttgctctcg cgaacgtaat
    35821 gatccaacgt aaccttgaga aaatcgcgcc agtcatccag cgttaatcct ttttcctgcc
    35881 agtgcaaggg gctcttatgt attttctcca gcccctggta accaacctga accagcccct
    35941 gtgtttccag gctgttagtc cgtttagggc gacgcatgaa ttcccggaac aacaacattt
    36001 cagaaagctt aagggggccg ccgttttcat taaacacttc aggcttaaga taatggttat
    36061 attgcagaac cggcccgcgg atatcggctc tctctttaag ctcgttaacc atctccgtcc
    36121 aggttcggga taccaggata gtcgcggctt tcccaccggt tgcagcctga taagcctgtt
    36181 caagctgttc agcctgtgct tgtgacaatt tcgcctggtc tggcattccc cagcttcgat
    36241 attcttctgc ctgctcacgg gcttgcttcg ccctggccgc taatttttcc agatcggcat
    36301 tggcattcgg cgctgtagac gtttgcgtcc tttgatgcca gctgagaatt tcgactacgc
    36361 ttccgcgtaa gcgactgcgt tctgcttctt gctgcatacg caccgccatt cgggctgtcc
    36421 cttgtcgact gtctgtaaag gtgatgagtc gacgacctcg tcctggcaac gaatctggtc
    36481 cgacgccctc tttgccttca tcactggtaa agtcctgaca atactctaga acggtgggca
    36541 cgatattagt aacgtaaaat ggcccaccta atagtgcacg ccggaagggc tgtttcccac
    36601 tcatgcctct gtagccacag ccactggcac tacaaacctg ttcaatatca ttaataatca
    36661 gcggaatgct gtcattgtta ataacgccaa tacggcgcgt ctgacggtcg aggcgttgta
    36721 gggtataacc tgcctcgctg gtctctcctg cggcaataat caacggaggc tgaaaactgt
    36781 tctctttttc gactttttct tctgtagcgt catgttcaac aggtacttca tcctgcaaag
    36841 agaattcatc gccaccttta ttttcccact ggactagttt gccctttttg tcccgtgcca
    36901 gaagatgagg ctcattacaa tcattacaga atgcaacttc gtatacaggg cttccacagt
    36961 cacaattttg tcgctggttc acatacacat agccaaaggg ccagcctttg tcgagcggtg
    37021 taccgtgctt taatctgcaa tctttatcaa cacaagccca tattccctgg gtattacgct
    37081 ggaagatatg cgccctgact ttaagaaatg cgggatcctt tgcattaggt tgagtccctg
    37141 aacagacatc gatccaacgc agtacttcct gctggctgta atgctgtttt gtcagcacgt
    37201 gtaaccgctc tgttatctca tccagcttca tcggattggg ctgtttgacc aacatctcac
    37261 gtatgtaacg cgcttcgggg gaatgcgtaa gcgcataaaa gcgctcagga cttatccctt
    37321 taattttatt atcattttta tctcttagat ccagatcagg tatttgctct atctcgtcta
    37381 acggaacaga aacgtttttg gatggttcca gttcaggaat cacccgactt ccgtccagaa
    37441 catcgatgcg ctcctgcggg ataccggata attcagagag aaattttttc agctgctttt
    37501 cagcgtcgct gccggcaatg gtcgcagagg tcgcgacaaa gcgcacgtca tctggtgtca
    37561 cgccaaacgc ggtcatcaca cgacgcagct ggagcgccag ttcagcggcc tgcgacccta
    37621 cataggtatg cgcttcatcc agtacaatcc agcgtagtga tttttgtgct ttagattgct
    37681 ggataatcgg ggcgtcgacc tggcgaacca tcatatattc cagcatcgtg ccgttggtca
    37741 ccagaatcgg cgcaggttct tcacgcattt tttcgcgcga gagcacctca ttcggccttt
    37801 ttgcctgttc gctttttacc gaagcgtgta ggttttcggt gttgccgttg taaaggcagt
    37861 agcggatccc tgtaccaaaa ccacgcgtcc aggcatccag acgctcgcgc tgtgaattaa
    37921 tcagggcgtt caatggatag agaaaaaggg ctcggacacc gaccaacgga ttgttgccat
    37981 tttcatgcag ttcccggtaa agatcttcca gcaccggtac cataaaacat tccgttttac
    38041 ctgaacccgt accactggtt accaccactg aatgtttctt ttccagcaaa gctttccaac
    38101 tggctaactg gtgcgtaaaa ggcctccagt cagcaccaaa ccggtaccgg ccattattct
    38161 gatcatccag tgaatcaacc actgctttgc tcaacaatgc gttgccttcc gtcaggctgc
    38221 gcatcgtgtg gtttgactcc ttccagccaa acatttgctg gaataccgga gaagcaagga
    38281 atgagcccgg tttcccacaa tcagccccca tttgttgcgc gagatgttca cgcagctgcg
    38341 ggttggtaac gcccatgata ctgagcgttg cttcagttga acgagacaac gattgttcaa
    38401 taagtgacga aaaatagcgt gtagtcatcc ttattccttt ttatttttta gcaacataac
    38461 gcaacaggct gcactggaag atggccttaa accagcggga atcgaaatcc ctgacttgcc
    38521 tcaggaaaaa tacggcaccg ggtttacggt caaatacaga ttcaaaagaa gcatttccgc
    38581 ttgccacagc tgcagcgaag acgggtaaca aggccacgga atagcggtga tttgcgtcag
    38641 gattaatacc aatcactgga tttttttgtg atgccatcca gctatgcagc cgcttgctgc
    38701 cgtactctgg ccattgagct tcactatgct cacgtaaaag ctcctgatac cacacgtgga
    38761 caaaagactc aggaatagac ggggggagat gtccgttact taaccatttc tcaatttcat
    38821 cggcatatgt cgggaacacg agccccagcc gttgaaacat attagtaacc agtaatttct
    38881 gggtttcctc cggtgcacct ttttggctca ggaacaattt gaaacgctca gatgccgctt
    38941 tgatctcaaa gatggggaaa aactcccata gaatagggaa ctcattctca atacgactca
    39001 ggtactctgc tgacatttca aatttgaaga gcgacattgc caatgcctgc ggatgctgca
    39061 ccagtgcacg ccatacttca aaggttgcca gtggtaaata accaaattga tcgtacaggc
    39121 tacgcataaa ttgccagccg gaatgggcag gatcgttagc catctgtccg agaaccagtg
    39181 tgatggtatt aacttctgcc tgtggattaa aaagctgggt cgctttctgc aatgagcgga
    39241 tgttgctttc ttctaccggt aacgaagatt cgccacgaat gaagcaggga cgaaaagcca
    39301 tctcttcacc cggtttaggg acaaccaacc acggtccatt tttgttaacg attgagctca
    39361 actcatattc accgacaggc actccctcgc tcattcttga tgctaagggg atggatttcc
    39421 tctcgggttc acttaacagc atgataacgg gggaaggaat ctgtccagca cgatggttca
    39481 ctgactggct gagtaatagt tctttttcat aatcatagcg cagactgtat ttatagcgac
    39541 gaatttgcca ggccatgacc acacccgccc ccgtaatacg catctcaaca acctggtcaa
    39601 tacctgcctc aagtgaaatc aggttctcaa tatgttcgcg cagactatag agattcaatt
    39661 caacaggacg atcgctcaac gccgtataac accattcgtg ccatgcctgt aatccactaa
    39721 cggagcgcaa atgcaactgc aatgtatatc ttgtcggctc gccatttctg gagaacagaa
    39781 acgctctgga acccagcaga tcatgcagcg taatgttttt atccagagga cgtccgttta
    39841 catcaagagc gagacagcct ttagcgggaa aaggtaactc aatatcgatg gggtcagccg
    39901 ccaaattagg cagaacttgt aatgtaataa atgccggagg taccccttcc gctttgagtt
    39961 gtatctctgt tcgcccctca gtacgcttac gtgtagcctc caatgtttta tctttaagtt
    40021 ttgctacaca aggatgctgt gtggtgatta cgatagtgcc ttcatttgcg tgtattccac
    40081 cttttatctc aatactgaaa tcagcaggca aaataccgat tttgcgacgc aagagcgttt
    40141 cattcttact attacggata gaaagatatt gagcccccag catctcttgt atatgacatt
    40201 gctcaattga aattccgctc aggtaacgcg ttacatcaat gctttgaata tccggtagtg
    40261 tagaaatgac ttttggtaca ccaataaatg tttcatctgg atgacaaacc cagcttgcac
    40321 gctttccatt tagagcaaac cttccgatgc tgatttgttc tcttccggtg cgaatccgat
    40381 aagtttcatt tgctgtaact gtaacgtcct gacatccctt cacaggtagt gcttttagtc
    40441 ctaatacgtt tactgccctc gattggccat caaaaccagc aacattgcta ttatcccgag
    40501 ggagcacaat cagaacatcg ctgcttcgca cactgcaaga agcctgtccc tgtaacagcc
    40561 attgatctgc atcaacgatg aaggttaacg gcacctcacc aatggcaatt tcactgtcat
    40621 caagtttaat gctcccaaca atcatccctc cagcacgagc cactaacgac aaacctgccg
    40681 atggattttg cctgccaaat ctcacttcgc ttttacgtaa tcgaactgtt gcctgtctgt
    40741 tttccagaga agcataggct ggcccaaggc cagagacttc ctcaccatct tcacaaatgg
    40801 caagttcaaa gcgcgtagtt gacggctcgc ttgttacagg aaaggaaact tcgtccggaa
    40861 gagatactat caccctaagc tcatctggat gcttttctga ccaatagaat tggcaacgcg
    40921 tactcttatt tttttgtagt cgaggcttag cctctacaga ggctgcgcat agcagtccat
    40981 tcaaaaaatg cgttcctgtt tcatcatcta acggtattgg aaactcgctt cgccaggtag
    41041 ggtgaacctt ctcaagctgt tgtactggtt ctttgtgatt tattaggttg tgagtaagta
    41101 ctaaggaatt gaggttatca gccatatgac tgataagttc tacagaggta tcttcgctaa
    41161 aaacagttgg cagcgctgat ttttctatga cagctcttgc cagcgaaagg gcagaaaaac
    41221 ctgactgctt tgcttgctca tattgtccaa ggatcctgga gaaaacagcc agaaagcgac
    41281 tgtctgattc tttgagtagc cggaaaggta aaccaccttc actgaataat gttccgagaa
    41341 aattgcgtcg ttcagattca taaaatcgaa ttgggcgcag ccagtaatct tccatccctt
    41401 tcggtacgat agtaccaagc tctgtggcgg tgaatgaaat ccctattttt ttatatatag
    41461 ggtcccacgt ccatccgcat tgccgttcat aatccctgcg gtaccactca gagcaaaaaa
    41521 gaacaaaaca ggcagcaaag tccctattac atatattaga ttgtgattga ccgactgcac
    41581 ggagtagctg cgttaattgg gtatattcat cattggttgc atgatattca taaagaggac
    41641 ggccatccgg ttgtctcaac cctctaagat tcacaaagtt acttagccag gaagtacatt
    41701 ttacccatga aatgtattct gattgaccca aagcaagctc cttagagata aaagatacaa
    41761 aaacaaaacc ccacaacatt tctaatttga aagaaaacct ttcagaatat tgtatagtta
    41821 ctcaggcggc aacaactatt ttttcaggtc gatactataa atcaatttta gataaaaatg
    41881 atatcaac
//
LOCUS       DAPHKZ010000028        41847 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.028, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000028 DAPHKZ010000000
VERSION     DAPHKZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41847
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.028"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            333..419
                     /gene="leuL"
                     /locus_tag="RH288_001595"
     CDS             333..419
                     /gene="leuL"
                     /locus_tag="RH288_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HDV4030664.1"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     gene            512..2083
                     /gene="leuA"
                     /locus_tag="RH288_001596"
     CDS             512..2083
                     /gene="leuA"
                     /locus_tag="RH288_001596"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDV4030665.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITEYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     gene            2083..3174
                     /gene="leuB"
                     /locus_tag="RH288_001597"
     CDS             2083..3174
                     /gene="leuB"
                     /locus_tag="RH288_001597"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDV4030666.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            3177..4577
                     /gene="leuC"
                     /locus_tag="RH288_001598"
     CDS             3177..4577
                     /gene="leuC"
                     /locus_tag="RH288_001598"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDV4030667.1"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     gene            4588..5193
                     /gene="leuD"
                     /locus_tag="RH288_001599"
     CDS             4588..5193
                     /gene="leuD"
                     /locus_tag="RH288_001599"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDV4030668.1"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN"
     gene            complement(5242..6420)
                     /gene="setA"
                     /locus_tag="RH288_001600"
     CDS             complement(5242..6420)
                     /gene="setA"
                     /locus_tag="RH288_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetA"
                     /protein_id="HDV4030669.1"
                     /translation="MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREV
                     GAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRH
                     YLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPL
                     AFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVR
                     MLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVK
                     RYGKRRMMVIAVAAGVLFYTGLIFFNSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMP
                     GRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
                     "
     gene            complement(6522..6653)
                     /gene="sgrT"
                     /locus_tag="RH288_001601"
     CDS             complement(6522..6653)
                     /gene="sgrT"
                     /locus_tag="RH288_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HDV4030670.1"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES"
     gene            6742..8397
                     /gene="sgrR"
                     /locus_tag="RH288_001602"
     CDS             6742..8397
                     /gene="sgrR"
                     /locus_tag="RH288_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SgrR"
                     /protein_id="HDV4030671.1"
                     /translation="MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     IKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLKIKEIDYDQWHTGEIES
                     DIWLNSANFTLPLDFSVFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLLHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     regulatory      8431..8530
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8561..9544
                     /gene="thiB"
                     /locus_tag="RH288_001603"
     CDS             8561..9544
                     /gene="thiB"
                     /locus_tag="RH288_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HDV4030672.1"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     ADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
                     STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     gene            9520..11130
                     /gene="thiP"
                     /locus_tag="RH288_001604"
     CDS             9520..11130
                     /gene="thiP"
                     /locus_tag="RH288_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HDV4030673.1"
                     /translation="MATRRQPLIPGWLIPGVSATTLVVAVALAAFLALWWNAPQDDWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVIPAIFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLATLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRSWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALLQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQVLEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRPLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKLPGRNVKTD"
     gene            11114..11812
                     /gene="thiQ"
                     /locus_tag="RH288_001605"
     CDS             11114..11812
                     /gene="thiQ"
                     /locus_tag="RH288_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HDV4030674.1"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGSLTIDGVDHTTMPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAVQQGKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELL
                     SGKASASALLGITG"
     gene            complement(11926..12690)
                     /locus_tag="RH288_001606"
     CDS             complement(11926..12690)
                     /locus_tag="RH288_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV4030675.1"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWLAGIIGCLMGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
     gene            complement(12776..13654)
                     /gene="araC"
                     /locus_tag="RH288_001607"
     CDS             complement(12776..13654)
                     /gene="araC"
                     /locus_tag="RH288_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HDV4030676.1"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCEEKVNDVAVKLS"
     gene            13993..15693
                     /gene="araB"
                     /locus_tag="RH288_001608"
     CDS             13993..15693
                     /gene="araB"
                     /locus_tag="RH288_001608"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HDV4030677.1"
                     /translation="MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHEIWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKTQINASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
                     "
     gene            15704..17206
                     /gene="araA"
                     /locus_tag="RH288_001609"
     CDS             15704..17206
                     /gene="araA"
                     /locus_tag="RH288_001609"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDV4030678.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGKKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     gene            17321..18016
                     /gene="araD"
                     /locus_tag="RH288_001610"
     CDS             17321..18016
                     /gene="araD"
                     /locus_tag="RH288_001610"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDV4030679.1"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPS
                     GVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     gene            18091..20442
                     /gene="polB"
                     /locus_tag="RH288_001611"
     CDS             18091..20442
                     /gene="polB"
                     /locus_tag="RH288_001611"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HDV4030680.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPQLLEKLNAWFANYDPD
                     VIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     gene            20607..23513
                     /gene="rapA"
                     /locus_tag="RH288_001612"
     CDS             20607..23513
                     /gene="rapA"
                     /locus_tag="RH288_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HDV4030681.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     gene            23525..24184
                     /gene="rluA"
                     /locus_tag="RH288_001613"
     CDS             23525..24184
                     /gene="rluA"
                     /locus_tag="RH288_001613"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HDV4030682.1"
                     /translation="MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     gene            24397..24575
                     /locus_tag="RH288_001614"
                     /pseudo
     CDS             24397..24575
                     /locus_tag="RH288_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244358.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(24592..24750)
                     /locus_tag="RH288_001615"
     CDS             complement(24592..24750)
                     /locus_tag="RH288_001615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030683.1"
                     /translation="MNGATSLYDEVIIINKIPPKKIDTKGVATEEVATKKVLLNKLLT
                     TQLLNEPE"
     gene            complement(24747..25398)
                     /locus_tag="RH288_001616"
                     /pseudo
     CDS             complement(24747..25398)
                     /locus_tag="RH288_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518734.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25693..26508)
                     /gene="djlA"
                     /locus_tag="RH288_001617"
     CDS             complement(25693..26508)
                     /gene="djlA"
                     /locus_tag="RH288_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HDV4030684.1"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     gene            26763..29117
                     /gene="lptD"
                     /locus_tag="RH288_001618"
     CDS             26763..29117
                     /gene="lptD"
                     /locus_tag="RH288_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HDV4030685.1"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     gene            29170..30456
                     /gene="surA"
                     /locus_tag="RH288_001619"
     CDS             29170..30456
                     /gene="surA"
                     /locus_tag="RH288_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HDV4030686.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     gene            30456..31445
                     /gene="pdxA"
                     /locus_tag="RH288_001620"
     CDS             30456..31445
                     /gene="pdxA"
                     /locus_tag="RH288_001620"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HDV4030687.1"
                     /translation="MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLT
                     NRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRAPVTAGQLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLNELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     gene            31442..32263
                     /gene="rsmA"
                     /locus_tag="RH288_001621"
     CDS             31442..32263
                     /gene="rsmA"
                     /locus_tag="RH288_001621"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDV4030688.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAE
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     gene            32266..32643
                     /gene="apaG"
                     /locus_tag="RH288_001622"
     CDS             32266..32643
                     /gene="apaG"
                     /locus_tag="RH288_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HDV4030689.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     gene            32650..33492
                     /gene="apaH"
                     /locus_tag="RH288_001623"
     CDS             32650..33492
                     /gene="apaH"
                     /locus_tag="RH288_001623"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HDV4030690.1"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGE
                     AAAS"
     gene            complement(33570..34049)
                     /gene="folA"
                     /locus_tag="RH288_001624"
     CDS             complement(33570..34049)
                     /gene="folA"
                     /locus_tag="RH288_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HDV4030691.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            complement(34241..36103)
                     /gene="kefC"
                     /locus_tag="RH288_001625"
     CDS             complement(34241..36103)
                     /gene="kefC"
                     /locus_tag="RH288_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HDV4030692.1"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGCGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     gene            complement(36096..36626)
                     /gene="kefF"
                     /locus_tag="RH288_001626"
     CDS             complement(36096..36626)
                     /gene="kefF"
                     /locus_tag="RH288_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HDV4030693.1"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     gene            complement(36734..38065)
                     /locus_tag="RH288_001627"
     CDS             complement(36734..38065)
                     /locus_tag="RH288_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4030694.1"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     gene            complement(38122..38409)
                     /gene="fixX"
                     /locus_tag="RH288_001628"
     CDS             complement(38122..38409)
                     /gene="fixX"
                     /locus_tag="RH288_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HDV4030695.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     gene            complement(38406..39692)
                     /locus_tag="RH288_001629"
     CDS             complement(38406..39692)
                     /locus_tag="RH288_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDV4030696.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     gene            complement(39743..40684)
                     /locus_tag="RH288_001630"
     CDS             complement(39743..40684)
                     /locus_tag="RH288_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDV4030697.1"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQA
                     IQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     gene            complement(40699..41469)
                     /locus_tag="RH288_001631"
     CDS             complement(40699..41469)
                     /locus_tag="RH288_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HDV4030698.1"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     ALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
BASE COUNT        10129 a        11477 c        10848 g         9393 t
ORIGIN      
        1 tcaataatat tcaccaaatc aatatcaaaa aaaaatcgca aaacatataa ttcaatacaa
       61 atcatcagga taggttttgc aacgcgtgca ttttgtcccc tttttcctcg ttgattagat
      121 gcaaaaattt atgctgaaat atgtcaaccg atgaaaagcg tcggtagtta agcagaaatt
      181 aatatcgctt actttaacca ccgcagcaca attagctaat tttacggatg cagaactcac
      241 gctggcggga cgtttttatt gcgtcagggt tgacatccgt ttttgtatcc agtaactcta
      301 aaagcatatc gcattcatct ggagctgatt taatgactca catcgttcgc tttatcggtc
      361 tactactact aaacgcatct tctttgcgcg gtagacgagt gagcggcatc cagcattaag
      421 ccagcacgca gtcaaacaaa aaacccgcgc cattgcgcgg gtttttttat gcccgaagcg
      481 aggcgctcta aaagagacaa ggacccaaac catgagccag caagtcatta ttttcgatac
      541 cacattgcgc gacggtgaac aggcgttaca ggcaagcttg agtgtgaaag aaaaactgca
      601 aattgcgctg gcccttgagc gtatgggtgt tgacgtgatg gaagtcggtt tccccgtctc
      661 ttcgccgggt gattttgaat cagtgcaaac catcgcccgc caggttaaaa acagccgcgt
      721 atgcgcgtta gctcgctgcg tggagaaaga tatcgacgtg gcggccgaat ccctgaaagt
      781 cgccgaagcc ttccgtattc atacctttat tgccacttcg ccaatgcaca tcgccaccaa
      841 gctgcgcagc acgctggatg aagtgatcga acgcgctatc tatatggtga aacgcgcccg
      901 taattacacc gatgatgttg aattttcttg cgaagatgcc gggcgtacac ccattgccga
      961 tctggcgcga gtggtcgaag cggcgattaa tgccggtgcc accaccatca acattccgga
     1021 caccgtgggc tacaccatgc cgtttgagtt cgccggaatc atcagcggcc tgtatgaacg
     1081 cgtacctaac atcgacaaag ccattatttc cgtacatacc cacgacgatt taggcctggc
     1141 ggtcggcaac tcactggcgg cggtacatgc cggtgcacgc caggtggaag gtgcaatgaa
     1201 cgggatcggc gagcgtgccg gaaactgttc cctggaagaa gtcatcatgg cgatcaaagt
     1261 tcgtaaggat attctcaacg tccacacagc cattaatcac caggagatat ggcgcaccag
     1321 ccagttagtt agccagattt gtaatatgcc gatcccggca aacaaagcca ttgttggcag
     1381 cggcgcattc gcacactcct ccggtataca ccaggatggc gtgctgaaaa accgcgaaaa
     1441 ctacgaaatc atgacaccag aatctattgg tctgaaccaa atccagctga atctgacctc
     1501 tcgttcgggg cgtgcggcgg tgaaacatcg catggatgag atggggtata aagaaagtga
     1561 atataattta gacaatttgt acgatgcttt cctgaagctg gcggacaaaa aaggtcaggt
     1621 gtttgattac gatctggagg cgctggcctt catcggtaag cagcaagaag agccggagca
     1681 tttccgtctg gattacttca gcgtgcagtc tggctctaac gatatcgcca ccgccgccgt
     1741 caaactggcc tgtggcgaag aagtcaaagc agaagccgcc aacggtaacg gtccggtcga
     1801 tgccgtctat caggcaatta accgcatcac tgaatataac gtcgaactgg tgaaatacag
     1861 cctgaccgcc aaaggccacg gtaaagatgc gctgggtcag gtggatatcg tcgctaacta
     1921 caacggtcgc cgcttccacg gcgtcggcct ggctaccgat attgtcgagt catctgccaa
     1981 agccatggtg cacgttctga acaatatctg gcgtgccgca gaagtcgaaa aagagttgca
     2041 acgcaaagct caacacaacg aaaacaacaa ggaaaccgtg tgatgtcgaa gaattaccat
     2101 attgccgtat tgccggggga cggtattggt ccggaagtga tgacccaggc gctgaaagtg
     2161 ctggatgccg tgcgcaaccg ctttgcgatg cgcatcacca ccagccatta cgatgtaggc
     2221 ggcgcagcca ttgataacca cgggcaacca ctgccgcctg cgacggttga aggttgtgag
     2281 caagccgatg ccgtgctgtt tggctcggta ggcggcccga agtgggaaca tttaccacca
     2341 gaccagcaac cagaacgcgg cgcgctgctg cctctgcgta agcacttcaa attattcagc
     2401 aacctgcgcc cggcaaaact gtatcagggg ctggaagcat tctgtccgct gcgtgcagac
     2461 attgccgcaa acggcttcga catcctgtgt gtgcgcgaac tgaccggcgg catctatttc
     2521 ggtcagccaa aaggccgcga aggtagcgga caatatgaaa aagcctttga taccgaggtg
     2581 tatcaccgtt ttgagatcga acgtatcgcc cgcatcgcgt ttgaatctgc tcgcaagcgt
     2641 cgccacaaag tgacgtcgat cgataaagcc aacgtgctgc aatcctctat tttatggcgg
     2701 gagatcgtta acgagatcgc cacggaatac ccggatgtcg aactggcgca tatgtacatc
     2761 gacaacgcca ccatgcagct gattaaagat ccatcacagt ttgacgttct gctgtgctcc
     2821 aacctgtttg gcgacattct gtctgacgag tgcgcaatga tcactggctc gatggggatg
     2881 ttgccttccg ccagcctgaa cgagcaaggt tttggactgt atgaaccggc gggcggctcg
     2941 gcaccagata tcgcaggcaa aaacatcgcc aacccgattg cacaaatcct ttcgctggca
     3001 ctgctgctgc gttacagcct ggatgccgat gatgcggctt gcgccattga acgcgccatt
     3061 aaccgcgcat tagaagaagg cattcgcacc ggggatttag cccgtggcgc tgccgccgtt
     3121 agtaccgatg aaatgggcga tatcattgcc cgctatgtag cagaaggggt gtaatcatgg
     3181 ctaagacgtt atacgaaaaa ttgttcgacg ctcacgttgt gtacgaagcc gaaaacgaaa
     3241 ccccactgtt atatatcgac cgccacctgg tgcatgaagt gacctcaccg caggcgttcg
     3301 atggtctgcg cgcccacggt cgcccggtac gtcagccggg caaaaccttc gctaccatgg
     3361 atcacaacgt ctctacccag accaaagaca ttaatgcctg cggtgaaatg gcgcgtatcc
     3421 agatgcagga actgatcaaa aactgcaaag aatttggcgt cgaactgtat gacctgaatc
     3481 acccgtatca ggggatcgtc cacgtaatgg ggccggaaca gggcgtcacc ttgccgggga
     3541 tgaccattgt ctgcggcgac tcgcataccg ccacccacgg cgcgtttggc gcactggcct
     3601 ttggtatcgg cacttccgaa gttgaacacg tactggcaac gcaaaccctg aaacagggcc
     3661 gcgcaaaaac catgaaaatt gaagtccagg gcaaagccgc gccgggcatt accgcaaaag
     3721 atatcgtgct ggcaattatc ggtaaaaccg gtagcgcagg cggcaccggg catgtggtgg
     3781 agttttgcgg cgaagcaatc cgtgatttaa gcatggaagg tcgtatgacc ctgtgcaata
     3841 tggcaatcga aatgggcgca aaagccggtc tggttgcacc ggacgaaacc acctttaact
     3901 atgtcaaagg ccgtctgcat gcgccgaaag gcaaagattt cgacgacgcc gttgcctact
     3961 ggaaaaccct gcaaaccgac gaaggcgcaa ctttcgatac cgttgtcact ctgcaagcag
     4021 aagaaatttc accgcaggtc acctggggca ccaatcccgg ccaggtgatt tccgtgaacg
     4081 acaatattcc cgatccggct tcgtttgccg atccggttga acgcgcgtcg gcagaaaaag
     4141 cgctggccta tatggggctg aaaccgggta ttccgctgac cgaagtggct atcgacaaag
     4201 tgtttatcgg ttcctgtacc aactcgcgca ttgaagattt acgcgcggca gcggagatcg
     4261 ccaaagggcg aaaagtcgcg ccaggcgtgc aggcactggt ggttcccggc tctggcccgg
     4321 taaaagccca ggcggaagcg gaaggtctgg ataaaatctt tattgaagcc ggttttgaat
     4381 ggcgcttgcc tggctgctca atgtgtctgg cgatgaacaa cgaccgtctg aatccgggcg
     4441 aacgttgtgc ctccaccagc aaccgtaact ttgaaggccg ccaggggcgc ggcgggcgca
     4501 cgcatctggt cagcccggca atggctgccg ctgctgctgt gaccggacat ttcgccgaca
     4561 ttcgcaacat taaataagga gcacaccatg gcagagaaat ttatcaaaca cacaggcctg
     4621 gtggttccgc tggatgccgc caatgtcgat accgatgcaa tcatcccgaa acagtttttg
     4681 cagaaagtga cccgtacggg ttttggcgcg catctgttta acgactggcg ttttctggat
     4741 gaaaaaggcc aacagccaaa cccggacttc gtgctgaact tcccgcagta tcagggcgct
     4801 tccattttgc tggcacgaga aaacttcggc tgtggctctt cgcgtgagca cgcgccctgg
     4861 gcattgaccg actacggttt taaagtggtg attgcgccga gttttgctga catcttctac
     4921 ggcaatagct ttaacaacca gctgctgccg gtgaaattaa gcgatgcaga agtggacgaa
     4981 ctgtttgcgc tggtgaaagc taatccgggg atccatttcg acgtggatct ggaagcgcaa
     5041 gaggtgaaag cgggagagaa aacctatcgc tttaccatcg atgccttccg ccgccactgc
     5101 atgatgaacg gtctggacag tattgggctt accttgcagc acgacgacgc cattgccgct
     5161 tatgaagcaa aacaacctgc gtttatgaat taatcccctt gcccggtcaa atgaccgggc
     5221 tttccgctat cgtccacgtc atcaaacgtc tttaaccttt gcggttaaaa ataatgcgac
     5281 aacagaaata accgcaatta cccagtagac agcaaagtgc ccccaacttt gtgcaattgc
     5341 tccctgaata acgccagcca gaattacccc ggtagaaata ctgttagtaa ataaggtggt
     5401 agctgccccc gctcttccag gcattaaatc ctgaaaccat agcatcccaa tacccgcaac
     5461 aatgccgata aatacagcgt taaaaagttg cagcgtcatc aacgccatac ggctattaaa
     5521 gaaaatcaat ccggtgtaaa acagtactcc tgccgccact gctatgacca tcattcgccg
     5581 cttaccataa cgtttgacat agtagccagc cagaatcatt gctggtattt ccagtccagc
     5641 tgccgtcccc atcaggaaac ccgccagttt gtctggcaat cctaactcgc tactgatcca
     5701 caacggcata tcaataatgt acatggtgtt gcaggtccac attaacgtcg aggcgacaaa
     5761 taacatccgt acgttactat cctgccagcc accttgcatt gataaagcat tttccgacgg
     5821 cagttctacc cgcgccacag acggaagcat aaatgcaatc aataccagac tgagtgtgaa
     5881 tatcccggcg gcaatcgaaa acatcaccgt aaagccgtaa ttcaacgcca gcataaaggc
     5941 caacggtgga ccgataaccc atgccagaga aagctgcgca cgcatcaccg agctaaacat
     6001 caccacttct cgcgccgagt tatccgcata ttcccgcgcc agagcaaata actgtggcat
     6061 tgccgtattg gccagagatg ccagaagcac accacaggtg ataagcgtca gataatgacg
     6121 attaaatgca aacaatagcg cattgccgat agccatcaaa cagcaaaata taatcagttt
     6181 tcgccgatcg ccctgactgt cagaacgttt tgccaaccag aggcttacgc cgatcccagc
     6241 aatagcattc accgtataaa agaggccgat ccagaaaggt tgcgcgccaa cctcacgact
     6301 cagaaataag ctcaatgtag gagcctgtag cgccccggcc acccccatca taaaagcgac
     6361 cagcataaat gccgcgtaaa caccgttcat acggcgagcc atcgtcatta tccagatcat
     6421 acgttccctt tttagcgcgg cgagaataaa aaaaaccagc aggtataatc tgctggcggg
     6481 tgattttaca ccaatactca gtcacacatg atgcaggcaa gtcaactttc agaattgcgg
     6541 tcatcccact gcatcagtcc ttcaagcatg gttaatcgtt gtgggacgct taaccaacgc
     6601 aaccagcaca acttcgctgt cgcggtaaaa tagtgctgat aaaactgacg catggggcac
     6661 ccccttgctt catcgttagg aattattgac ttaatatagg gaaaataaaa ttgctgtctt
     6721 ttgcacagga gttccccttt tatgccatct gctcgtctgc aacaacagtt catccgcctg
     6781 tggcaatgct gcgagggtaa atcgcaggac acaacgctca acgaactggc agcgttattg
     6841 agctgctcgc gtcgtcatat gcgcaccctg ctcaacacca tgcaggatcg cggctggctg
     6901 acgtgggaag cggaagtcgg gcgcggtaaa cgctcgcgtc tgacattcct ctataccggg
     6961 ctggcgcttc agcaacagcg ggcggaagac ctgctggagc aggatcgtat cgatcaactg
     7021 gtgcagttgg ttggcgacaa agcgactgtg cggcaaatgc tggtttctca tctgggccgc
     7081 agcttccgcc aggggcggca catcctgcgc gtgctctact atcgtccgtt gcgtaatctg
     7141 ctacctggca gcgcattgcg ccgttccgaa acccatatcg cccggcaaat cttcagttcg
     7201 ctaacgcgca taaatgagga aaatggggaa ctggaagcag acatcgccca ccactggcag
     7261 caaatttcac cgcttcactg gcgtttcttt ttgcgtccag gagtccattt tcaccatggt
     7321 cgtgaactgg aaatggacga tgtgatcgcc tctttaaaac gaatcaatac gctgccgctc
     7381 tattcgcata ttgctgacat tgtgtcgccg acgccctgga cgctggatat ccatctcacg
     7441 caaccggacc gctggttacc gttactgctg gggcaagttc cggcgatgat cctgccgcgc
     7501 gaatgggaaa ccctcagtaa ctttgccagc catcccatcg gcaccggtcc gtatgcggtg
     7561 attcgcaaca gcaccaatca actgaaaatt caggcattcg atgacttctt cggttaccgg
     7621 gcattaatcg acgaagttaa cgtctgggtt ctgccggaaa ttgccgacga gccagccgga
     7681 gggctgatgc taaaaggtcc acagggcgag gaaaaagaga ttgaaagccg cctggaggaa
     7741 ggttgctact atttactgtt cgacagccgc acccatcgcg gggcgaatca gcaagtcagg
     7801 gactgggtaa gctatgtgct ttctccaact aatctggtct atttcgctga ggaacagtac
     7861 cagcaactgt ggttcccggc ttatggactg ctcccccgtt ggcaccatgc ccgcaccata
     7921 aagagcgaaa aaccggctgg cctggaaagc ctcaccctaa ccttttatca ggatcacagt
     7981 gagcatcggg tgattgccgg gatcatgcag cagattctgg caagtcacca ggtcacgctg
     8041 aaaatcaaag agatcgacta cgatcagtgg catacaggag agatcgaaag tgatatctgg
     8101 ctaaacagcg ccaactttac cctgccgctg gacttctctg ttttcgcaca tttatgcgaa
     8161 gtgccactgc tacaacattg cattcccatt gactggcaag ccgacgctgc tcgctggcgc
     8221 aatggcgaga tgaatctggc gaactggtgc cagcaactgg tcgccagcaa agcgatggtg
     8281 ccattattgc accactggct gatcattcag gggcaacgca gtatgcgcgg cctgcgcatg
     8341 aataccctcg gctggttcga ttttaaatca gcgtggtttg cgccaccgga tccatgattg
     8401 ctggttgata acaaaatcac tacactaacg ccgttctcaa cggggtgcca cgcgtacgcg
     8461 tgcgctgaga aaatacccgt cgaacctgat ccggataacg ccggcgaagg gatttgaggc
     8521 tccttctcaa gtcctttgcc actctttttt gaggtgcaaa gtgttaaaaa aatgtctgcc
     8581 cctgctgttg ctgtgcacag cgcccgtttt cgctaaaccc gttctgactg tttataccta
     8641 cgattccttc gccgccgact gggggcctgg tccggtggtt aaaaaagcct ttgaagccga
     8701 ctgtaattgc gaactgaaac tggtggcgct ggaagatggc gtttcgcttc tcaaccgtct
     8761 acggatggaa ggcaaaaaca gtaaagccga tgtggtgctg gggctggata acaacctgtt
     8821 agacgccgcc agtaaaaccg gactgtttgc caaaagcggt gtggcagcgg atgccgttaa
     8881 cgttcccggc ggctggaata atgacacttt cgtaccgttt gattatggct acttcgcctt
     8941 cgtttatgac aagaacaaac tgaaaaaccc gccacaaagc ctgaaagaac tggttgagag
     9001 cgatcaaaac tggcgggtga tttatcagga tccgcgcacc agtacaccgg ggctgggtct
     9061 gttgctatgg atgcaaaaag tctatggcga tgacgcccca caagcctggc agaaactggc
     9121 gaagaaaacg gtcacggtca ccaaaggctg gagcgaagcc tacggcctgt ttttaaaagg
     9181 tgaaagcgat ctggtactga gttacaccac ctctccggct tatcacattc tcgaagagaa
     9241 gaaagataac tacgccgccg cgaacttcag cgaaggtcac tatctgcaag tggaagtcgc
     9301 cgcccgcacc gctgccagca agcagccgga gctggcgcaa aaattcctcc agtttatggt
     9361 ttctccggct ttccagaatg cgatcccaac cggcaactgg atgtatccgg tggcaaacgt
     9421 cacgctgcct gccggttttg aaaaattgac caaacccgca accacgttgg agttcacgcc
     9481 agccgaagtg gcggcacaac gtcaggcatg gattagcgaa tggcaacgcg ccgtcagccg
     9541 ttaattcccg gctggttaat tccaggtgta agcgccacca cgctggtggt agcggttgcg
     9601 ctggcggcgt ttctcgccct gtggtggaac gcgccgcagg atgactgggt ggcagtctgg
     9661 caggacagct atctgtggca tgtggtgcgc ttctccttct ggcaggcgtt tctctcggca
     9721 ctgctctctg tcatacccgc gatattcctc gcccgcgcgc tctatcgcag gcgctttccg
     9781 ggtcggctgg cgctgttgcg tctgtgtgca atgaccttga tcctcccggt gttggtcgct
     9841 gttttcggca ttcttagcgt ctatggtcgc cagggctggc tggcaacact ctgccaatcg
     9901 ctcggtctgg agtggacctt ttcgccctac ggcctgcaag gtattttgct ggcccatgtg
     9961 ttttttaatc tgccgatggc gagccgctta ttactccagg cactggaaaa catccccggc
    10021 gaacagcgtc aacttgccgc ccagcttggg atgcgtagct ggcatttttt ccgcttcgtc
    10081 gaatggccgt ggttacggcg acaaatcccg ccggttgctg cgcttatctt tatgctctgt
    10141 ttcgccagct tcgccaccgt gctatcgctg gggggcggtc cgcaggcgac cactatcgag
    10201 ctggcaatct atcaggcgct gagttacgac tacgatcctg cccgcgcggc aatgctggcg
    10261 ctgctccaga tggtgtgctg cctcgggctg gtgctgttga gtcagcgatt gagtaaggcc
    10321 attgcgcccg gcaccacgct gctgcaaggc tggcgcgacc cggacgatcg tctgcatagc
    10381 cgcatttgcg acacggtgtt aattgtgctg gcgctgctgc tgttgctgcc accgttactg
    10441 gcggtgatcg tcgatggggt aaatcgccag ttgccggaag tgctggcaca accggtgctg
    10501 tggcaggcgc tgtggacctc gttgcgtatt gcgctggcgg caggtgtatt gtgcgtagtg
    10561 ctgaccatga tgctgctatg gagcagtcgc gaactgcggg cgcggcagaa aatgctggcg
    10621 ggtcaggtgc tggagatgag cggcatgttg atcctcgcca tgccggggat tgtgctggct
    10681 accggcttct ttttactgct caacaacact atcggcctgc cacaatctgc tgacggcatt
    10741 gtgattttca ccaatgcgtt aatggcgatc ccttatgcgc tgaaagtgct ggaaaacccg
    10801 atgcgcgata tcaccgcccg ctacagcatg ttatgtcagt cgctggggat tgaaggctgg
    10861 tcacgcttaa aagtggtgga gctgcgcgcc ctgaaacgtc cactggcgca ggcgctggcc
    10921 tttgcatgcg tgctgtcgat tggtgatttt ggcgtggtgg cgttgttcgg taacgatgat
    10981 ttccgccccc tgccgtttta tctctaccag caaattggct cctatcgcag ccaggacggt
    11041 gcggtcaccg cgttaattct gctgctgctc tgttttctgc tgtttaccgt gattgaaaaa
    11101 ctaccggggc gaaatgttaa aactgactga tatcacctgg ctttaccacc atttgccgat
    11161 gcgttttagc ttaacggtgg aacgcggcga gcaggtggcg atcctcgggc caagcggcgc
    11221 gggtaaaagt accctgctga atttgatcgc cggttttctg acgccagcca gcggttcgct
    11281 gactatcgat ggcgtagatc acacaactat gccgccgtca cgccgtccgg tgtcgatgct
    11341 gtttcaggag aacaacctgt tcagccacct gacggtcgca cagaacatcg ggctggggct
    11401 aaatccggga ttgaaactga acgcggtaca gcaggggaaa atgcacgcta tcgcccgcca
    11461 gatggggatt gataatttaa tggcgcggtt accgggcgag ctttccggcg gtcagcgaca
    11521 gcgagtggcg ttagcgcgtt gtctggtacg cgaacagccg attttattgc tcgatgaacc
    11581 gttctctgcg ctcgatccgg cgttacgtca ggagatgttg acgctggtga gcacgagctg
    11641 ccagcagcaa aaaatgacgc tattgatggt gtcgcacagc gtggaagatg cggcgcggat
    11701 cgccacgcgc tcggtagtag tcgccgacgg gcgcatcgcc tggcagggta tgaccaatga
    11761 gttgttgagc ggtaaggcga gtgcttcggc actattgggg attacgggtt agtatgcact
    11821 gtcggatgcg gcgtgaacgc cttatccgac ctacgggtag tgcgttttgt aggcctgata
    11881 agacgcggca agcgtcgcat caggcaaccc gcacaagact atctcctaaa ccccaaccac
    11941 tttacgcaaa atatcgatat acaccggcat caacgggtgg cgaattaaca ccaccagcgc
    12001 caccacgccg atggcagaaa tcaacggcgt cagccacaac aaacgaccgc gggacaaata
    12061 atgactcaaa cggtcagtcg ctttaccgct gcgccataac cgccagcaca gccagccacc
    12121 aacccacaaa aacaccgctg ttgccagcag caaccattta aactcaccgc tctgcattcc
    12181 ggcaggaata tcgatcgccg cgcccgccag aatccctggc aggaagtaaa acggcggcca
    12241 cagcaggcag ccgataatat tcggcgtaat aaatttagcc accggcagat ccagcattcc
    12301 cgccaccatt ggcaccagcg gacgcgtcgg gccaacaaaa cgaccgacca gaatggtgaa
    12361 catgctgtgt tgatgcaacg catgttcagt tttatcaagt agtgctttgt ttttcttcag
    12421 aaatgaccag cgatgcaacg gctttttaaa acgccaaccc agccagaaag aaatccagtc
    12481 gcccatcaag cagccaataa tccctgccag ccaggcgtgc cagaaactta actcgccgct
    12541 gccaatcagc gctcccagcc ccgccatcag caccgtaccg ggtagaatca aaccgaccag
    12601 cgccagcgac tccagaaagg ccaccaacac caccgccatc aatgaataca cggtggattg
    12661 ggtaataaag tgttccagca atgcttgcat aatgtgcctg tcaaatggac gaagcaggga
    12721 ttctgcaaac cctatgctac tccgtcaagc cgtcaattgt ctgattcgtt accaattatg
    12781 acaacttgac ggctacatca ttcacttttt cttcacaacc ggcacgaaac tcgctcgggc
    12841 tggccccggt gcatttttta aatactcgcg agaaatagag ttgatcgtca aaaccaacat
    12901 tgcgaccgac ggtggcgata ggcatccggg tagtgctcaa aagcagcttc gcctgactaa
    12961 tgcgttggtc ctcgcgccag cttaagacgc taatccctaa ctgctggcgg aaaagatgtg
    13021 acagacgcga cggcgacaag caaacatgct gtgcgacgct ggcgatatca aaattgctgt
    13081 ctgccaggtg atcgctgatg tactgacaag cctcgcgtac ccgattatcc atcggtggat
    13141 ggagcgactc gttaatcgct tccatgcgcc gcagtaacaa ttgctcaagc agatttatcg
    13201 ccagcagctc cgaatagcgc ccttcccctt gcccggcgtt aatgatttgc ccaaacaggt
    13261 cgctgaaatg cggctggtgc gcttcatccg ggcgaaagaa acccgtattg gcaaatattg
    13321 acggccagtt aagccattca tgccagtagg cgcgcggacg aaagtaaacc cactggtgat
    13381 accattcgcg agcctccgga tgacgaccgt agtgatgaat ctctcctggc gggaacagca
    13441 aaatatcacc cggtcggcag acaaattctc gtccctgatt tttcaccacc ccctgaccgc
    13501 gaatggtgag attgagaata taacctttca ttcccagcgg tcggtcgata aaaaaatcga
    13561 gataaccgtt ggcctcaatc ggcgttaaac ccgccaccag atgggcgtta aacgagtatc
    13621 ccggcagcag gggatcattt tgcgcttcag ccatactttt catactccca ccattcagag
    13681 aagaaaccaa ttgtccatat tgcatcagac attgccgtca ctgcgtcttt tactggctct
    13741 tctcgctaac ccaaccggta accccgctta ttaaaagcat tctgtaacaa agcgggacca
    13801 aagccatgac aaaaacgcgt aacaaaagtg tctataatca cggcagaaaa gtccacattg
    13861 attatttgca cggcgtcaca ctttgctatg ccatagcatt tttatccata agattagcgg
    13921 atcctacctg acgcttttta tcgcaactct ctactgtttc tccatacccg tttttttgga
    13981 tggagtgaaa cgatggcgat tgcaattggc ctcgattttg gcagtgattc tgtgcgagct
    14041 ttggcggtgg actgcgctac cggtgaagag atcgccacca gcgtagagtg gtatccccgt
    14101 tggcagaaag ggcaattttg tgatgccccg aataaccagt tccgtcatca tccgcgtgac
    14161 tacattgagt caatggaagc ggcactgaaa accgtgcttg cagagcttag cgtcgaacag
    14221 cgcgcagctg tggtcgggat tggcgttgac agtaccggct cgacgcccgc accgattgat
    14281 gccgacggaa acgtgctggc gctgcgcccg gagtttgccg aaaacccgaa cgcgatgttc
    14341 gtattgtgga aagaccacac tgcggttgaa gaagcggaag agattacccg tttgtgccac
    14401 gcgccgggca acgttgacta ctcccgctac attggtggta tttattccag cgaatggttc
    14461 tgggcaaaaa tcctgcatgt gactcgccag gacagcgccg tggcgcaatc tgccgcatcg
    14521 tggattgagc tgtgcgactg ggtgccagct ctgctttccg gtaccacccg cccgcaggat
    14581 attcgtcgcg gacgttgcag cgccgggcat aaatctctgt ggcacgaaat ctggggcggc
    14641 ctgccgccag ccagtttctt tgatgagctg gacccgatcc tcaatcgcca tttgccttcc
    14701 ccgctgttca ctgacacttg gactgccgat attccggtgg gcaccttatg cccggaatgg
    14761 gcgcagcgtc tcggcctgcc tgaaagcgtg gtgatttccg gcggcgcgtt tgactgccat
    14821 atgggcgcag ttggcgcagg cgcacagcct aacgcactgg taaaagttat cggtacttcc
    14881 acctgcgaca ttctgattgc cgacaaacag agcgttggcg agcgggcagt taaaggtatt
    14941 tgcggtcagg ttgatggcag cgtggtgcct ggatttatcg gtctggaagc aggccaatcg
    15001 gcgtttggtg atatctacgc ctggtttggt cgcgtactcg gctggccgct ggaacagctt
    15061 gccgcccagc atccggaact gaaaacgcaa atcaacgcca gccagaaaca actgcttccg
    15121 gcgctgaccg aagcatgggc caaaaatccg tctctggatc acctgccggt ggtgctcgac
    15181 tggtttaacg gccgccgcac accgaacgct aaccaacgcc tgaaaggggt gattaccgat
    15241 cttaacctcg ctaccgacgc tccgctgctg ttcggcggtt tgattgctgc caccgccttt
    15301 ggcgcacgcg caatcatgga gtgctttacc gatcagggga tcgccgttaa taacgtgatg
    15361 gcactgggcg gcatcgcgcg gaaaaaccag gtcattatgc aggcctgctg cgacgtgctg
    15421 aatcgcccgc tgcaaattgt tgcctctgac cagtgctgtg cgctcggtgc ggcgattttt
    15481 gctgccgtcg ccgcgaaagt gcacgcagac atcccatcag ctcagcaaaa aatggccagt
    15541 gcggtagaga aaaccctgca accgtgcagc gagcaggcac aacgctttga acagctttat
    15601 cgccgctatc agcaatgggc gatgagcgcc gaacaacact atcttccaac ttccgccccg
    15661 gcacaggctg cccaggccgt tgcgactcta taaggacacg ataatgacga tttttgataa
    15721 ttatgaagtg tggtttgtca ttggcagcca gcatctgtat ggcccggaaa ccctgcgtca
    15781 ggtcacccaa catgccgagc acgtcgttaa tgcgctgaat acggaagcga aactgccctg
    15841 caaactggtg ttgaaaccgc tgggcaccac gccggatgaa atcaccgcta tttgccgcga
    15901 cgcgaattac gacgatcgtt gcgctggtct ggtggtgtgg ctgcacacct tctccccggc
    15961 caaaatgtgg atcaacggcc tgaccatgct caacaaaccg ttgctgcaat tccacaccca
    16021 gttcaacgcg gcgctgccgt gggacagtat cgatatggac tttatgaacc tgaaccagac
    16081 tgcacatggc ggtcgcgagt tcggcttcat tggcgcgcgt atgcgtcagc aacatgccgt
    16141 ggttaccggt cactggcagg ataaacaagc ccatgagcgt atcggctcct ggatgcgtca
    16201 ggcggtctct aaacaggata cccgtcatct gaaagtctgc cgatttggcg ataacatgcg
    16261 tgaagtggcg gtcaccgatg gcgataaagt tgccgcacag atcaagttcg gtttctccgt
    16321 caatacctgg gcggttggcg atctggtgca ggtggtgaac tccatcagcg acggcgatgt
    16381 taacgcgctg gtcgatgagt acgaaagctg ctacaccatg acgcctgcca cacaaatcca
    16441 cggcaaaaaa cgacagaacg tgctggaagc ggcgcgtatt gagctgggga tgaagcgttt
    16501 cctggaacaa ggtggcttcc acgcgttcac caccaccttt gaagatttgc acggtctgaa
    16561 acagcttcct ggtctggccg tacagcgtct gatgcagcag ggttacggct ttgcgggcga
    16621 aggcgactgg aaaactgccg ccctgcttcg catcatgaag gtgatgtcaa ccggtctgca
    16681 gggcggcacc tcctttatgg aggactacac ctatcacttc gagaaaggta atgacctggt
    16741 gctcggctcc catatgctgg aagtctgccc gtcgatcgcc gcagaagaga aaccgatcct
    16801 cgacgttcag catctcggta ttggtggtaa ggacgatcct gcccgcctga tcttcaatac
    16861 ccaaaccggc ccagcgattg tcgccagctt gattgatctc ggcgatcgtt accgtctact
    16921 ggttaactgc atcgacacgg tgaaaacacc gcactccctg ccgaaactgc cggtggcgaa
    16981 tgcgctgtgg aaagcgcaac cggatctgcc aactgcttcc gaagcgtgga tcctcgctgg
    17041 tggcgcgcac cataccgtct tcagccatgc actgaacctc aacgatatgc gccaattcgc
    17101 cgagatgcac gacattgaaa tcacggtgat tgataacgac acacgcctgc cagcgtttaa
    17161 agacgcgctg cgctggaacg aagtgtatta cgggtttcgt cgctaagtag ccgcatccgg
    17221 tatgtaacgc ctgatgcgac gctgacgcgt cttatctggc ctacacgctg cgattttgta
    17281 ggccggataa gcaaagcgca tccggcacga aggagtcaac atgttagaag atctcaaacg
    17341 ccaggtatta gaagccaacc tggcgctgcc aaaacacaac ctggtcacgc tcacatgggg
    17401 caacgtcagc gccgttgatc gcgagcgcgg cgtctttgtg atcaaacctt ccggcgtcga
    17461 ttacagcgtc atgaccgctg acgatatggt cgtggttagc atcgaaaccg gtgaagtggt
    17521 tgaaggtacg aaaaagccct cctccgacac gccaactcac cggctgctct atcaggcatt
    17581 cccctccatt ggcggcattg tgcatacgca ctcgcgccac gccaccatct gggcgcaggc
    17641 gggtcagtcg attccagcaa ccggcaccac ccacgccgac tatttctacg gcaccattcc
    17701 ctgcacccgc aaaatgaccg acgcagaaat caacggcgaa tatgagtggg aaaccggtaa
    17761 cgtcatcgta gaaacctttg aaaaacaggg tatcgatgca gcgcaaatgc ccggcgttct
    17821 ggtccattcc cacggcccgt ttgcatgggg caaaaatgcc gaagatgcgg tgcataacgc
    17881 catcgtgctg gaagaggtcg cttatatggg gatattctgc cgtcagttag cgccgcagtt
    17941 accggatatg cagcaaacgc tgctggataa acactatctg cgtaagcatg gcgcgaaggc
    18001 atattacggg cagtaatgac tgtataaaac cacagccaat caaacgaaac caggctatac
    18061 tcaagcctgg ttttttgatg gattttcagc gtggcgcagg caggttttat cttaacccga
    18121 cactggcggg acaccccgca agggacagaa gtctccttct ggctggcgac ggacaacggg
    18181 ccgttgcagg ttacgcttgc accgcaagag tccgtggcgt ttattcccgc cgatcaggtt
    18241 ccccgcgctc agcatatttt gcagggtgaa caaggctttc gcctgacacc gctggcgtta
    18301 aaggattttc accgccagcc ggtgtatggc ctttactgtc gcgcccatcg ccaattgatg
    18361 aattacgaaa agcgcctgcg tgaaggtggc gttaccgtct acgaggccga tgtgcgtccg
    18421 ccagaacgct atctgatgga gcggtttatc acctcaccgg tgtgggtcga gggtgatatg
    18481 cacaatggca ctatcgttaa tgcccgtctg aaaccgcatc ccgactatcg tccgccgctc
    18541 aagtgggttt ctatagatat tgaaaccacc cgccacggtg agctgtactg catcggcctg
    18601 gaaggctgcg ggcagcgcat cgtttatatg ctggggccgg agaatggcga cgcctcctcg
    18661 cttgatttcg aactggaata cgtcgccagc cgcccgcagt tgctggaaaa actcaacgcc
    18721 tggtttgcca actacgatcc tgatgtgatc atcggttgga acgtggtgca gttcgatctg
    18781 cgaatgctgc aaaaacatgc cgagcgttac cgtcttccgc tgcgtcttgg gcgcgataat
    18841 agcgagctgg agtggcgcga gcacggcttt aaaaacggcg tcttttttgc ccaggctaaa
    18901 ggtcggctaa ttatcgacgg tatcgaggcg ctgaaatccg cgttctggaa tttctcttca
    18961 ttctcgctgg aaactgtcgc tcaggagcta ttaggcgaag gaaaatctat cgataacccg
    19021 tgggatcgaa tggacgaaat tgaccgccgt ttcgccgaag ataaacctgc gctggcaact
    19081 tataacctga aagattgcga gctggtgacg cagatcttcc acaaaactga aatcatgcca
    19141 tttttactcg aacgggcaac ggtgaacggc ctgccggtgg accgacacgg cggttcggtg
    19201 gcggcatttg gtcatctcta ttttccgcga atgcatcgcg ctggttatgt cgcgcctaat
    19261 ctcggcgaag tgccgccgca cgccagccct ggcggctacg tgatggattc acggccaggg
    19321 ctttatgatt cagtgctggt gctggactat aaaagcctgt acccgtcgat catccgcacc
    19381 tttctgattg atcccgtcgg gctggtggaa ggcatggcgc agcctgatcc agagcacagt
    19441 accgaaggtt ttctcgatgc ctggttctcg cgagaaaaac attgcctgcc ggagattgtg
    19501 actaacatct ggcacgggcg cgatgaagcc aaacgccagg gtaacaaacc gctgtcgcag
    19561 gcgctgaaaa tcatcatgaa tgccttttat ggcgtgctcg gcaccaccgc ctgccgcttc
    19621 ttcgatccgc ggctggcatc gtcgatcacc atgcgtggtc atcagatcat gcggcaaacc
    19681 aaagcgttga ttgaagcaca gggctacgac gttatctacg gcgataccga ctcaacgttt
    19741 gtctggctga aaggcgcaca ttcggaagaa gaagcggcga aaatcggtcg tgcactggtg
    19801 cagcacgtta acgcctggtg ggcggaaacg ctgcaaaaac aacggctgac cagcgcatta
    19861 gaactggagt atgaaaccca tttctgccgt tttctgatgc caaccattcg cggagccgat
    19921 accggcagta aaaagcgtta tgccggactg attcaggagg gcgacaagca gcggatggtg
    19981 tttaaagggc tggaaaccgt gcgcaccgac tggacgccgc tggcccagca gtttcagcag
    20041 gagctatacc tgcgcatctt ccgcaacgag ccatatcagg aatatgtacg cgaaaccatc
    20101 gacaaactga tggcgggtga actggatgcg cgactggttt accgtaaacg ccttcgccgt
    20161 ccgctgagcg agtatcagcg taatgtgccg cctcatgtac gcgccgctcg ccttgccgat
    20221 gaagaaaacc aaaagcgtgg tcgccccttg caatatcaga atcgcggcac cattaagtac
    20281 gtatggacca ccaacggccc ggagccgctg gactaccaac gttcaccact ggattacgaa
    20341 cactatctga cccgccagct acaacccgtg gcggagggaa tactcccttt tattgaggat
    20401 aattttgcta cacttatgac cgggcaactt gggctatttt gagcaaaaaa aagagttcgc
    20461 cagataccat tttgatgcgt gacgaatgct ttgccatcca gtaccatagc gccctttcca
    20521 ttcctggacc tgaataacac cactacctca taagcacggt agcgggtggt tattgcctgc
    20581 aattaaagat atagagccga acacatatgc cttttacact tggtcaacgc tggatcagcg
    20641 atacagaaag cgaattggga cttggaaccg ttgtcgcggt ggatgcgcga actgtcactt
    20701 tacttttccc atctactggt gaaaaccgtc tgtacgcacg cagtgattcc cccgtgaccc
    20761 gcgtgatgtt caaccctggt gataccatta ccagccatga cggctggcag atgcaagtcg
    20821 aagaagtaaa agaagaaaat ggcttgctga cctatatcgg tactcgcctg gatactgaag
    20881 agtccggcgt agccctgcgt gaagttttcc ttgatagcaa actggtgttc agcaaaccgc
    20941 aggaccgtct gtttgccggg cagattgacc gtatggaccg ctttgcgctg cgttatcgcg
    21001 cgcgtaaata ttccagcgaa cagttccgta tgccgtacag cggcctgcgc ggtcagcgta
    21061 ccagcctgat cccgcatcag ctcaacatcg ctcatgatgt tggtcgccgc cacgcgccgc
    21121 gcgtcctgct ggctgacgaa gtgggtttag ggaaaaccat tgaagccggg atgatcctgc
    21181 atcagcaact gctctctggc gctgctgaac gtgtgctaat tatcgtcccg gaaaccttac
    21241 agcatcagtg gctggtagaa atgctgcgcc gtttcaacct gcgctttgcg ctatttgatg
    21301 atgagcgtta tgccgaagct cagcacgatg cttacaaccc gtttgacacc gaacagctgg
    21361 tgatttgctc gctggatttt gcccgtcgta gcaaacagcg cctggaacat ctctgtgaag
    21421 ccgaatggga cctgctggtg gtcgatgaag cgcatcacct ggtgtggagc gaagatgcgc
    21481 caagccgtga atatcaggcc attgaacaac tggcagagca cgtgccgggc gttctgctgc
    21541 tgaccgcgac cccggaacag ctggggatgg aaagccactt cgcccgtctg cgtctgctgg
    21601 acccgaaccg tttccacgat tttgcgcagt tcgttgaaga gcagaaaaat tatcgtccgg
    21661 ttgcggacgc cgttgccatg ctgctggcag gtaacaaact gagcaatgac gaactgaaca
    21721 tgctcggcga gatgatcggc gagcaggata tcgagccgct gttgcaggca gcaaacagcg
    21781 acagcgaaga tgcccagagc gcccgtcagg agctggtttc gatgctgatg gatcgccacg
    21841 gcaccagccg cgtgctgttc cgtaacacgc gtaacggtgt gaaaggattc ccgaaacgcg
    21901 agctgcacac cattaagctg ccgctaccga cgcagtatca gacggctatt aaagtctccg
    21961 gcattatggg cgcacgtaaa agtgcggaag atcgtgctcg cgatatgctc tacccggagc
    22021 gtatttatca ggaatttgaa ggtgataacg ccacctggtg gaacttcgat ccgcgcgttg
    22081 agtggctgat gggctacctg accagccatc gctctcagaa agtgctggtg atctgcgcca
    22141 aagctgccac tgcgctgcaa ctggagcagg tactgcgcga acgtgaaggt attcgcgctg
    22201 cggtgttcca cgaaggtatg tcgattatcg aacgtgaccg cgctgccgcc tggtttgccg
    22261 aagaagacac cggcgcacag gtactgctgt gctcagaaat cggttctgaa ggacgtaact
    22321 tccagttcgc cagccacatg gtgatgtttg acctgccatt caacccggat ctactggagc
    22381 agcgtattgg tcgtctggat cgtatcggcc aggcgcacga tattcagatc catgtgcctt
    22441 atctggagaa aaccgctcag tcggtgctgg tgcgctggta tcacgaaggt ctggatgcat
    22501 ttgagcacac ctgcccgacc ggacgcacta tttacgatag cgtatacaac gatctgatta
    22561 actatctggc ttcaccggat caaaccgaag gctttgacga tctgatcaaa aactgccgcg
    22621 agcaacatga agcgctgaaa gcacagctgg aacagggtcg tgaccgcctg ctggaaatcc
    22681 actccaacgg tggcgaaaaa gcccaggcac tggcagaaag cattgaagag caggatgacg
    22741 ataccaacct gatcgccttc gccatgaacc tgttcgatat tatcggtatc aatcaggacg
    22801 atcgcggcga caacatgatc gtgctgacgc cgtccgatca tatgctggtg ccggacttcc
    22861 ctggcctgtc ggaagatggc atcaccatca cctttgatcg tgaagtggcg ctggcgcgtg
    22921 aagatgcaca gtttattacc tgggagcatc cgctgatccg caacggtctg gatctgatcc
    22981 tttctggcga taccggtagc agcacgattt cactgttaaa aaacaaagcg ttgccggtag
    23041 gtacgctgtt ggtggaactg atttatgtgg ttgaagccca ggctccgaag cagttgcagc
    23101 tcaaccgctt cctgccaccg acgccggtac gtatgctgct ggataaaaac ggcaacaacc
    23161 tggcggcgca ggtagagttt gaaaccttta accgccagct taacgcggtt aaccgtcaca
    23221 ccggcagcaa actggttaac gccgtgcagc aggatgttca cgctatcctt caactgggtg
    23281 aagcgcagat cgagaaatct gcccgtgcat tgattgatgc agcgcgtaac gaagccgacg
    23341 aaaaactgtc tgccgagctg tctcgtctgg aagctctgcg tgcagtgaac ccgaacattc
    23401 gtgacgacga actgaccgcc attgagagca accgtcagca ggtaatggaa agcctggatc
    23461 aggcaggttg gcgtctggat gccctgcgtt tgatcgttgt aacgcatcag taacggagcc
    23521 gaaaatgggg atggaaaact acaatccacc gcaggaaccc tggttggtta tcctgtatca
    23581 ggatgaccat attatggtgg tcaacaagcc gagcggtttg ttgtcagtgc cgggtcgtct
    23641 ggaagagcac aaagacagcg tgatgacgcg cattcagcgt gattatccgc aggcagaatc
    23701 ggtgcatcgt ctggatatgg ctaccagcgg cgtgattgta gtggcgctga ccaaagccgc
    23761 ggagcgggag ttaaaacgcc agttccgcga gcgcgagccg aaaaagcagt atgtggcccg
    23821 cgtctggggg catccatccc ccgcagaagg tctggtggat ctgccgctga tttgcgactg
    23881 gccaaaccgc ccgaaacaga aagtctgtta cgaaacgggt aaacctgcgc agacggaata
    23941 tgaagtggtg gagtatgcgg cggataacac ggcaagagtg gtgttaaaac cgattaccgg
    24001 gcgttcgcat caattgcgtg tgcatatgct ggcgctgggt catccgattc tcggcgatcg
    24061 tttttatgca tcaccagaag cgagagcgat ggcaccacgt ttgttgctac atgcagagat
    24121 gttgacgatt acccatccgg cgtatggcaa tagtatgacg tttaaagcgc cagcggattt
    24181 ttaatctttc ctgtacgttt ataccctcat cctaagggct gcctcttgta cataaatccc
    24241 cgagtccggg gattttttgt ttctgccaaa ctgctttcag ttgttgcgtg tggctacgct
    24301 ttccattcgg taattccctt cctgctccac agcgaatttt tgaacttttt cttcacccgt
    24361 tgaccgtctc ttatatttca ttttaacggg tctgttatgg tcctttctga ttgttattca
    24421 tgggctaatt agcagtctgg ttggcgatgc ccatctcggt gatccgtgtc ctgcacgacg
    24481 ccttgcgtca ctagcctctt ctctagctca tcatgcaggt ctttctaatt gtgaaatcat
    24541 cccacgctac tgctaaggtt gaaggggcgt tccagcccct tcaaccttag cttattctgg
    24601 ctcattcaat aattgcgttg tcagtaattt gttcagcagt acttttttag tagcaacttc
    24661 ttcagtagca actcctttag tatcaatttt tttggggggg attttattaa taataattac
    24721 ctcatcatat agggaggtag caccgttcac ggtagcaccg tccaggatag caccgtccag
    24781 gttagcaccg tccggggtag caccgtccgg ggtagcaccg cccaggttag cattccaccc
    24841 aggtctctca taaaggatat cattgctacc tttcattgtt tttttaccaa ggtaacaatc
    24901 cctcatgtca acgccgggaa ggtaagcctt tctaagatca acgcccaagt taccttggcc
    24961 cttatgcagc tgcaacgtct gagtacatat cttattcttt tcaatgaaaa aagtgacact
    25021 taactcgata tccccgaagg tctgggcgac ccagcgcata ttgccctttg cgaccaactc
    25081 atccggattt tttgcgcatg ttttaagttt attgaataat tccaggctat tgataaactt
    25141 ttctctctca ttctcgttga tagccccagt aaagtattct gaggcgttga tgttgccagt
    25201 ctggttattc acgaaattga acagaagttt ataagcctca gtctgtttat ctgaccagaa
    25261 cagatggcgt aacgtctccc acaagcgttg aaagatattc atcttcacgt ccatcttgtc
    25321 cccgctcacc atcttataaa tatcgttctt gctcatattt aaaagtgtaa ccggcatgcc
    25381 tggaactgat actttcatgg taatagcctc gcattgagtt aaaaactcat gatgcgcgtt
    25441 ctgaataaat atactttcaa aaatcgctca ttcaggtatg tgttttttat ttttaagacg
    25501 taaaaatata attccgctcg tcgtaaagct ctcaacctta agcagggtca acgcgataaa
    25561 acctacagaa cccctcccgt aaaccgtgca ttgagcctgt ccaccattct gagtaaacgc
    25621 cttttctcaa agaagtgacc gccagggcgg ccacctttaa tcgtgggcag ttactcagca
    25681 tcatttacag ggtcatttaa accctttctg ctgctttatc agctcatatg cctgctgaat
    25741 ttcctgcgct ttctgcttcg ccatctccat catctcaggc ggcaaacctt tcgccaccag
    25801 cttatcggga tggtgttcac tcatcagctt acggtaggca cgtttgatgg tggtcgcatc
    25861 atccgtcggc ttcacgccca gcacattaca ggcatcttcc agcgttgggc cacgctgcgc
    25921 ttgctgccag ttaccaccgc cagtttgctg ctgataaccg ccgccaaact gtgcaccgcc
    25981 ctgcatcatg cgcaaaaact ggtcaaactg agcgcgggag atccctaatt cttctgcaat
    26041 gacatacagc accgcccgtt cattcgggtg cagtgaacca tcagcaaacg ccgcctgaat
    26101 ctggatctcc agaaacatac gaattaagtc aaaacgacca aagcagacac tgcgaaactg
    26161 gcgcatcttt tcgcgcagcg ggtaattgtc tgattttccc acccggaacg cattttgcgc
    26221 cgcagtacgg gaagcgccat gaagattcat tcggtccatc aactggctgg cgatatgaat
    26281 atcagcctcc gtgacgcgac ctttggattt ggttaaatgc cccatcactt caaaagtggt
    26341 ggcaaaaaac agcgcctgac gctcacgctg gttggcgaac cacgccattt tacggctacg
    26401 ggctttatca aacatatggc caattaacag gcctaacact acgccccaaa agccgccgcc
    26461 catcagtaag gccacggcca cgccaatgat ttttccccaa tactgcatat attccccaaa
    26521 tcgacacacg gatatcaggg ccatctccca caatataaag gtgcttttac cgttttccgg
    26581 ctgcggtcaa ttgtgggaca tcgcctataa tttgcattat catacctgtc attcaatgcc
    26641 gtgcctaaca ccactgacgc tattcggaca ggattaacac tagcgtagag atgacgagta
    26701 cgttagtctc tgaccgtttg tcacgcgcaa cgttaccgat gatggaacaa taaaatcaac
    26761 gtatgaaaaa acgtatcccc actctcctgg ccaccatgat tgccaccgcc ctttatagtc
    26821 aacagggact ggcagccgac ctcgcctcac agtgcatgtt gggcgtgcca agctatgacc
    26881 gtcctctggt acagggcgat accaatgact tacccgtgac tatcaatgct gaccacgcga
    26941 aaggggacta cccggatgac gccgtgttta ctggcagcgt ggatatcatg cagggtaaca
    27001 gccgtctgca ggccgacgaa gtgcagctcc atcaaaaaga ggcaccagga caaccggagc
    27061 cggtacgtac cgttgatgcg ctcggtaatg tccattacga cgataaccag gtgatcctca
    27121 aagggccgaa aggctgggcg aatctgaaca ccaaagatac caacgtctgg gaaggtgatt
    27181 accagatggt gggtcgccag ggtcgcggta aagcggacct gatgaaacaa cgtggcgaaa
    27241 accgctatac cattctggat aacggtagct ttacctcctg tctgccgggt tctgacacct
    27301 ggagcgtggt aggtagcgaa attattcatg accgcgaaga acaagttgcg gagatctgga
    27361 acgcccgctt taaggtgggt ccggtaccga tcttttatag cccctatttg cagttgccgg
    27421 tgggtgacaa acgtcgctct ggtttcttga tcccgaacgc caagtacacc accaccaact
    27481 actttgagtt ctacctgcca tattactgga acatcgcgcc aaatatggat gccaccatca
    27541 cgccgcatta tatgcatcgt cgtggcaaca tcatgtggga gaacgaattc cgctacctct
    27601 cccaggcggg cgctggcttg atggaactgg actatctgcc ttcagataaa gtctatgaag
    27661 atgaacaccc gaacgatgac agttcacgtc gttggttatt ctactggaac cactccgggg
    27721 tcatggatca ggtgtggcgt ttcaacgtcg actacaccaa ggtcagcgat cctagctact
    27781 tcaatgattt cgataacaag tacggttcca gtactgacgg ctacgcaacg caaaaattca
    27841 gcgttggcta tgcggtgcaa aacttcaatg ccaccgtttc aaccaagcag ttccaggttt
    27901 tcagcgaaca gaacaccagt agctactcgg cagagccgca gttagacgtt aattactacc
    27961 agaatgatgt tggtccgttt gatacgcgta tttacggcca ggcagtgcac tttgttaaca
    28021 ccagagacga catgcctgaa gcaacccgtg ttcacctgga accgaccatc aatttgccgc
    28081 tctctaataa ctggggcagc atcaataccg aagcgaagtt gctggcaacc cattatcagc
    28141 aaaccaatct tgactggtat aactccagaa acacgaccaa gctggacgaa tccgttaacc
    28201 gcgtaatgcc gcaattcaaa gttgacggca aaatggtctt tgaacgcgat atggaaatgc
    28261 tggctccggg ttatacccaa acgctggaac cgcgcgcgca gtatttgtac gtgccgtatc
    28321 gcgatcagag cgacatctat aactacgact cgtctctgct gcaatctgac tactctggcc
    28381 tgttccggga ccggacttac ggcggtcttg accgtattgc ctccgctaac caggtgacga
    28441 ccggtgtcac atctcgcata tatgatgatg ctgccgttga acgttttaat atttccgttg
    28501 gtcaaatcta ctatttcacg gagtctcgca ctggcgatga caacataaca tgggagaatg
    28561 acgacaaaac gggttcactg gtgtgggcag gcgatactta ctggcgtatc tccgagcgtt
    28621 ggggattgcg tggcgggatt cagtacgata cacgtctgga taacgtagcg accagtaact
    28681 ccagcattga ataccgtcgg gatgaagacc gtctggtaca gctgaattac cgttacgcca
    28741 gcccggaata tattcaggct acgctgccta agtactattc cactgctgag caatataaga
    28801 atggtatttc gcaggtaggt gctgtcgcca gctggccaat tgccgatcgt tggtccattg
    28861 ttggggccta ctactacgac accaatgcta acaagcaagc cgactctatg ttaggtgtgc
    28921 aatacagctc ctgctgctat gcaattcgcg tcggttacga gcggaagctg aacggttggg
    28981 ataacgataa acaacatgcg gtatatgaca acgcaatcgg ctttaacatc gaacttcgcg
    29041 gcctgagctc caactacggt ctgggtacgc aagagatgct gcgttcgaac attctgccgt
    29101 atcaaaacac tttgtgattt gttgatttac cacgtaatcc gcagtgcggt taattgaaat
    29161 ggaaaaagta tgaagaactg gaaaacgctg cttctcggta tcgccatgat cgcgaatacc
    29221 agtttcgctg ccccccaggt agtcgataaa gtcgcagccg tcgtcaataa cggcgtcgtg
    29281 ctggaaagcg acgttgatgg attaatgcag tcggtaaaac tgaacgctgc tcaggcaagg
    29341 cagcaacttc ctgatgacgc gacgctgcgc caccaaatca tggaacgttt gatcatggat
    29401 caaatcatcc tgcagatggg gcagaaaatg ggagtgaaaa tctccgatga gcagctggat
    29461 caggcgattg ctaacatcgc gaaacagaac aacatgacgc tggatcagat gcgcagccgt
    29521 ctggcttacg atggactgaa ctacaacacc tatcgtaacc agatccgcaa agagatgatt
    29581 atctctgaag tgcgtaacaa cgaggtgcgt cgtcgcatca ccatcctgcc gcaggaagtc
    29641 gaatccctgg cgcagcaggt gggtaaccaa aacgacgcca gcactgagct gaacctgagc
    29701 cacatcctga tcccgctgcc ggaaaacccg acctctgatc aggtgaacga agcggaaagc
    29761 caggcgcgcg ccattgtcga tcaggcgcgt aacggcgctg atttcggtaa gctggcgatt
    29821 gctcattctg ccgaccagca ggcgctgaac ggcggccaga tgggctgggg ccgtattcag
    29881 gagttgcccg ggatcttcgc ccaggcatta agcaccgcga agaaaggcga cattgttggc
    29941 ccgattcgtt ccggcgttgg cttccatatt ctgaaagtta acgacctgcg cggcgaaagc
    30001 aaaaatatct cggtgaccga agttcatgct cgccatattc tgctgaaacc gtcgccgatc
    30061 atgactgacg aacaggcccg tgtgaaactg gaacagattg ctgctgatat caagagtggt
    30121 aaaacgactt ttgctgccgc agcgaaagag ttctctcagg atccaggctc tgctaaccag
    30181 ggcggcgatc tcggctgggc tacaccagat attttcgatc cggccttccg tgacgccctg
    30241 actcgcctga acaaaggtca aatgagtgca ccggttcact cttcattcgg ctggcattta
    30301 atcgaactgc tggatacccg taatgtcgat aaaaccgacg ctgcgcagaa agatcgtgca
    30361 taccgcatgc tgatgaaccg taagttctcg gaagaagcag caagctggat gcaggaacaa
    30421 cgtgccagcg cctacgttaa aatcctgagc aactaatggt taaaacccaa cgtgttgtga
    30481 tcactcccgg cgagcccgcc gggattggcc cggacttagt tgtccagctt gcacagcgtg
    30541 agtggccggt cgaactggtt gtttgtgccg atgccactct ccttaccaac cgggcagcga
    30601 tgctcggttt gccgctcacc ctccgccctt attcccccaa ctcccctgca caaccgcaaa
    30661 ctgcgggcac attaacgcta cttcctgtcg cgctacgtgc acctgtcact gcggggcagt
    30721 tagcggttga aaatgggcat tatgtggtgg aaacgctggc gcgagcgtgc gatggttgtc
    30781 tgaacggcga atttgccgcg ctgatcacag gtccggtgca taaaggcgtt attaacgacg
    30841 ctggcattcc ttttaccggt cataccgagt ttttcgaaga gcgttcgcag gcgaaaaagg
    30901 tggtgatgat gctggcgacc gaagaacttc gcgtggcgct ggcaacgacg catttaccgc
    30961 tgcgcgatat cgcagacgct atcacccctg cacttttgca cgaagtgatt gctattttgc
    31021 atcacgattt gcggaccaaa tttggtattg ccgaaccgcg cattctggtc tgcgggctga
    31081 atccgcacgc gggcgaaggc ggtcatatgg gtacggaaga gatagacacc attattccgg
    31141 tgctcaatga gctgcgggcg caggggatga aactcaacgg gccgctgcct gccgataccc
    31201 tgtttcagcc gaaatatctt gataacgccg acgccgtgct ggcgatgtac cacgatcagg
    31261 gtcttcccgt gctaaaatac cagggcttcg ggcgcggtgt gaacattacg ctgggcctgc
    31321 cctttattcg cacatcagtg gaccacggca ccgcgcttga actggcggga cgtggcaaag
    31381 ccgatgtcgg cagttttatt acggcgctta atctcgccat caaaatgatt gttaacaccc
    31441 aatgaataat cgagtccacc agggccactt agcccgtaaa cgcttcgggc aaaactttct
    31501 caacgatcag ttcgtgatcg acagtattgt gtctgccatt aacccgcaaa agggccaggc
    31561 gatggtcgaa atcggccccg gtctggcggc attgaccgaa ccggtcggcg aacgtctgga
    31621 ccagctgacg gtcatcgaac ttgaccgcga tctggcggca cgtctgcaaa cgcatccatt
    31681 cttaggcccg aaactgacga tttatcagca ggatgcgatg acctttaact ttggtgaact
    31741 ggccgagaaa atgggtcagc cgctgcgtgt tttcggcaac ctgccttata acatctccac
    31801 gccgttgatg ttccatctgt ttagctatac tgatgccatt gccgacatgc actttatgtt
    31861 gcaaaaagag gtggtgaatc gtctggttgc aggaccgaac agcaaagcgt atggtcgatt
    31921 aagcgtcatg gcgcaatact attgcaatgt gatcccggta ctggaagtac cgccgtcagc
    31981 ctttacacca ccacccaaag tggattccgc cgtcgtgcgc ctggttcctc atgcaacgat
    32041 gcctcacccg gttaaagatg ttcgtgtgtt gagccgcatc accaccgaag cctttaacca
    32101 gcgtcgtaaa accattcgta acagcctcgg caacctgttt agcgtcgagg tgttaacggg
    32161 aatggggatc gacccggcga tgcgagcgga aaatatctct gtcgcgcaat attgccagat
    32221 ggcgaactat ctggcggaga acgcgccttt gcaggagagt taacgatgat caattcgccc
    32281 cgagtgtgta ttcaggttca aagcgtctac attgaggctc aatcttcacc tgataatgaa
    32341 cgttacgttt ttgcttatac cgtaaccata cgcaatctgg ggcgagcgcc agtgcagttg
    32401 ttggggcgtt actggctgat caccaatggc aatggccgtg aaaccgaagt ccagggcgaa
    32461 ggagtggttg gcgtccagcc acttatcgcg cctggcgaag agtaccagta caccagcggt
    32521 gcaatcattg aaaccccgct gggcaccatg cagggtcact acgaaatgat cgatgaaaat
    32581 ggcgtccctt tcagcatcga cattcccgta ttccgactcg ccgttcccac actcattcat
    32641 taaaagaata tggcgacata ccttattggc gacgttcatg gttgttacga tgaactgatc
    32701 gcattgctgc ataaagtaga atttacccct gggaaagata ccctctggct gacgggcgat
    32761 ctggtcgcgc gcgggccggg ttcgctggat gttctgcgct atgtgaaatc cttaggcgac
    32821 agcgtacgtc tggtgctggg caatcacgat ctgcatctgc tggcggtatt tgccgggatc
    32881 agccgcaata aaccgaaaga tcgcctgaca ccgctgctgg aagcgccgga tgccgacgag
    32941 ctgcttaact ggctgcggcg ccagcctctg ctgcaaatcg acgaagagaa aaagctggtg
    33001 atggcccacg cagggatcac gccgcagtgg gatctgcaga ccgccaaaga gtgcgcacgc
    33061 gatgtagaag cggtgctatc gagtgactcc tatcccttct ttcttgatgc catgtacggc
    33121 gatatgccaa ataactggtc accggaattg cgggggctgg gaagactgcg ttttatcacc
    33181 aacgctttta cccgtatgcg tttttgcttc ccgaacggtc aactggatat gtacagcaaa
    33241 gaatcgccgg aagaggcccc tgccccactg aaaccgtggt ttgcgattcc tggccctgtc
    33301 gctgaagaat acagcatcgc ctttggtcac tgggcatcgc tggagggcaa aggtacgccg
    33361 gaaggtatat acgcgctgga taccggctgc tgctggggtg gtacattaac ctgcctgcgc
    33421 tgggaagata aacagtattt tgtccagccg tcgaaccggc ataaggattt gggcgaagcg
    33481 gcggcgtctt aaacacagcc tgatatagga aggccggata agacgcgacc ggcgtcgcat
    33541 ccggcgctag ccgtaaattc tatacaaaat taccgccgct ccagaatctc aaagcaatag
    33601 ctgtgagagt tctgcgcatc agcatcgtgg aattcgctga ataccgattc ccagtcatcc
    33661 ggctcgtaat ccgggaaatg ggtgtcgcct tccacttctg cgtcgatatg cgtcagatac
    33721 agtttttgcg cttttggcaa gaactgttca taaacgcgac cgccgccaat caccatgatt
    33781 tctggtacgt caccacacgc cgcgatggct tcatccaccg acttcaccca cgttacgcga
    33841 tcgtccgtac ccggttgact gctgaggata atatttttgc gtcctggcaa cggacgaccg
    33901 attgattccc aggtatggcg gcccataatc acgggtttat ttaaggtgtt gcgtttaaac
    33961 caggcgagat cggcaggcag gttccacggc atggcgtttt ccatgccgat aacgcgatct
    34021 accgctaacg ccgcaatcag actgatcatt gagatttccc gataaaaaaa attgtcgcca
    34081 ctatacgtaa agcgtaaacc gtcgtcgact ggtgcgagga tgatgttgag gaaaatttta
    34141 tattctgctg gcgagtccac gctctctccc tggactcgcc gcattacaat gaaacaaaaa
    34201 caaacagtta gctgtaaagt gtgatttacg tcactcttta ttaggatgag ggtttcgttt
    34261 ccggttcatc cgccatgttg ccggtatgtt taccttcttc ggttccctgc cagccatgtc
    34321 gttgaattaa tgacagatgt tcgcggtcct cggtaatgat ctcacttaac atcgcgctgg
    34381 tgcgtttata gaccgccgcg cgggctttgg tgtcgttctc aaccattgcc atctcttcca
    34441 ccatctgaat attaaagcgg cggaacacat cggcacgttc tcgcgcttca tacggcccca
    34501 gacctaaact ttccagtgcc agacgcccgg ttttcagcgc accttcgaag gtttcacgct
    34561 ccggcttttc aacgcctgcc tgacgcaaac gaatgtagtg gtcgacatcg cgggcgcggg
    34621 caataatctg caaatgcggg aaatgttctt tcaccatctc tgtcagttgc aggttggttt
    34681 gcggatcgtc gatggcgtta atcagcactt ccgctttcgc cgctccggca gattccagta
    34741 aatccatccg cgtggcatcg ccataaaaca ctttcatacc aaatttacgc aaggtttcga
    34801 tatggtccgg atcgtgatcg agtaccacca ttttcacccc gctggagagc agtaaacgtc
    34861 cggtaatctg cccaaaacga ccgaatccgg cgataatcac gcgcggctgt tcttcgtcga
    34921 tctcatcggc ttcacgcgct tcctcagtag aagattgctc aaggcgattg aggatcacca
    34981 gcagaatcgg cgttgctgcc atcgacagcg ccaccgccag ggtcagcgat ttcgcccact
    35041 ccggctccag cacattcgcc atctgcgccg cgccaaatac cacaaaggca aactcactgc
    35101 cctgccctaa caacaccgca aaccaacgac gctgtttatt tggcacttgc aacggtcggg
    35161 caatcagcca cagcatggcg attttgatga tgaggaaacc gagcagcaaa atgacaatgc
    35221 gcaatgggtt ttcaagcagc gtgccaaagt ctatcgacat gccaacaccg atgaaaaaca
    35281 gccccaacag caaaccttta aatggttcga tatcgctctc cagcgcatga cggtattccg
    35341 agcttgccag cagtacgccc gccagaaacg cgcccatcgc catcgacaag ccgacctctt
    35401 ccagcagcaa accaaagcca aacacgagga ataacgccac ggcactaaac acttcccgca
    35461 agccagagcg ggctacaaaa cgcagcgccg gacgcgtgac atagcgcccc agcaatacca
    35521 ccagcaccag cgcacccgcc acttttaacg ccgagagagc aaatgcgccc atcgtcgtcg
    35581 aggcactgct cgttgccagt agcggaatca tcgccaccag cgggatcgcc gcgatatcct
    35641 ggaacagcag caccgcaaag gcactgcgac ccatttgcgt caccatcaga ttgcgttcat
    35701 tcatcgcctg catggcaatc gccgtagagg agagcgccag cgtcatgccg atcaattccg
    35761 cgacctgcca gcgcagccca agtaacatgc agaacagccc cagcaggccg ccgcaaatca
    35821 ccatctgcaa tgcgccacag ccgaacactg ccgcacgcag cttccacagc ctttgtggat
    35881 cgagttcgag gccgataata aacagcatca gcaccacccc aatctcggca aagtgcagaa
    35941 tagattcggc atcggtcacc agtcgcagcc cccacgggcc aataatgcag ccggcgatca
    36001 ggtagccaag taccgatccc agaccaagac gtaccgcaat gggtacaatc agcgctgccg
    36061 aaccgagata aatcagcgcc tgaatcagcg tatggctatc catgatgggc ctcctgccat
    36121 tccagcagac gttgcttata gtgacgcgcc tgcccttcga gggtttcgtc gtcacaaata
    36181 aaggtgcagt gcatggcaaa cggtggcagc cagttcagcc cgcagtagat tgccgtcgcc
    36241 tgtagcggct gcgacagcac atcaaagccc ggatgcgcac caatttcaaa atggctttcc
    36301 ccgccgccgg tcgtcaccgc ccacagcaaa tgtttgccat gcagcgccgt gccgccatga
    36361 ccgtaagccc agccgtggga gaaaacttta tcgatccaaa gtttgaggag cggaggaatg
    36421 ctgtaccact gcatcggatg ctgccagacg atcagatcgg cgcgagacag cgcctcctgc
    36481 tcggcggcaa tatcgatatt gaagtcagga tagagttgat aaagagagcg aatttcgacg
    36541 ccttccagcg tccttgcctg ttcaagcatc cgtttattcg catgggaatg atgcggatac
    36601 ggatgcgcat aaattataag aatcataggt agcccgcgtg attacgcctt tgttttccca
    36661 caaagtgtag tcatatattc acgcggctta tagtcaataa tattgattca gaaaagagag
    36721 aaatctgaac aatttacccc attctctgcc cgcggatcgt catattgctg gtctgcgcca
    36781 gtgacatccc tcgagtctcc ggggcaaacg ctacggaaat caacaagcca aacagcgaga
    36841 tacccgcccc cattagcatc gtgttactga taccgtaatt attgataaag atcggtagtg
    36901 cccaggtcga aacaatggtg ccaatacgac ttaaggacat aatcacgccc acggcagagg
    36961 cgcggatatc tgtcgggaag agttcattag gatagagcca ctgcaaatta cccggcccgc
    37021 cagagaaaaa ggcatacacc gcaaaggcca tcactaccag ccagatcccc atatccggga
    37081 ttagccccaa aaccgccagc gccagcgtca tcatggcaaa gctgccaatc aacaatggac
    37141 gccgtccggc agtgtttaac cacagcatcg gcggaataca gccgagcata aagaacaggc
    37201 taatcaccac attccctagt gccgcgtttt tgccaacccc caatcccaac aaaccaacga
    37261 tttgcgggcc aaaggtgtaa atggcgaaca ttgggatcac ctggcaggtc cagatggcgg
    37321 caacaaacag aacaaaagga aaatggcggc gattaaacag atcgcgaaaa cgggtttgct
    37381 gcggctgctc ttcatcgaaa gccaccggtt cgccaaacag tttgatcatc atctcttcgc
    37441 actcttttac tcgccctttg cgtaataacc agcggggaga ttcaggcagt tcgaatcgac
    37501 caatcaaaat caacaaacag gggatcgccg cgctacccag catccagcgc cagccgcctt
    37561 ccacatcata aagccagtag ccgaccagat cggcacaggt cgcgccgaca taccacatcg
    37621 cggcaataaa gctgatggaa aacgcccgct gacgggtact ggagaactcg gtgatcattg
    37681 aggtggcgat gggataatct gcaccgatga caatgccgat aagtacccgc atcaccaaca
    37741 gttcgacggg ggatgaaaca aacatcgtcg ccaccgatat cacgccgatg gcgatgatat
    37801 caatgaggaa cattttgcgc cgtccgactt tatcggaaat ataaccaaac agcgatgtgc
    37861 caacgaacag cccggcgagc gttcccgcgc ccagcaagcc aatccagtca gcgtccagtt
    37921 tcagcgccgg cgtcagttgc tccagcgcca cgccaatcat taccagtaca taaccatcca
    37981 gaaacggacc accgcttccc cacagcaaaa tgcggcggtg aatagaggag aatttgagat
    38041 cgtcaaagtt tctggacggt tgcatggtta ttcctgtttt ttgcaatgag agtcagtgcg
    38101 gcgttacgta tcaaaccaac atcagccgta acggaactcc acaccaaagg tgccgcgcgg
    38161 gtattcccac tgttccagcg ccgaccccag ccccagaatg cgacaggtgc cgcactccag
    38221 acatccggcg taatcgaagc gcacactgcc gtcatcctgc ttcttgtaca gacctgcggg
    38281 gcacgctttc accagcagct ccagcgcctg tttatcagca tcggccttca caacaatgtg
    38341 cggatgctct tcatcgacat tgaatttatt gacgcccagt ttgacgtcca cattgacggg
    38401 agaagtcata aaacggtcac tcctttcatg ccatccttga ttagattgat gaagcccact
    38461 ttcttgccgt ggcggaggat tttcttgcgc atcagttccg gcgcgctgcc atcaatggtg
    38521 aacaggtcac gcgccacacc caccgccagc tccgggtagc cgctaaacat gcgtgggtta
    38581 tcaaggaacg ccggtagttt ctggtacata cgcatatcgc gcagcggacc actctcaaga
    38641 tgctgacgat attccgccag tttttgctta ctgaaatcgt cgcttttcat cgctgaaagc
    38701 acggtttttg ctgcggcttc cccggcggca atcgccagat ccataccgcg aatggtaaaa
    38761 ccgaggttca tacacattcc ggcggcatca ccggcaatca atacgccgtc accaaccaac
    38821 tccggcagca tgttgatgcc tgcttccggc actacgtgag cggaatattc caccagcttg
    38881 ccgcccgcga tcagcggtgc aacggccgga tgctgtttga aatcttccag catttgcggc
    38941 accgattttt tcgcgtcatg cagatgatgc aaaccacaaa ccagccccag cgacagggtg
    39001 ttttcattgg tataaaggaa gccgccgccc atcaggccat cggtgggtga tcccgcaaac
    39061 aggcaagccg ccccctgatt accctgcaac tgaaaacggt cttcaataac cgacttcggt
    39121 aactcgatca gttccttcac gccaaccgcc acatccgtcg gtttgacgcg ttttgccatc
    39181 cccaattttt cggcaaggat ggagttcacc ccatcagcaa ggatcaccgt tttcgcttca
    39241 atcacatcgc catcggcttc tacaccgacg actttgccat cgcgctgtac gaggttatcg
    39301 acgcggatcc cggtaattaa ctgcgcgccc gcttcttcgg cctgctccat cagccaggca
    39361 tcaaatttac tgcgcaaaac ggagtaagaa cgctgggatg gcgaggtttc gtcaccattg
    39421 cagtagtcca tagtcatcgc tgacttttcc gtcataaacg cgagtttttc atgggtgatc
    39481 aggcgttcta cgggggcgga gtcggcgaaa ccaggaataa tgtgttccag actgtgggca
    39541 tagagacgcc cgccggtgac gttcttggca cctgcggaat tgccacgctc gataactaac
    39601 acttgcgcac cttcgcgggc gagcaccagt gcggcaaccg aaccggcaag ccctgcaccg
    39661 acgatgatgg cgtcaaagat atcttcggac ataagagctc cctgtcagcg gcagggccaa
    39721 aatgcagccc tgccagagtg gatcaacgcg ctaaagctgc ggtcagcgcc ggaaggatct
    39781 tcacggcgtc gccaacaatg ccgtaatccg cgtactggaa gatcggcgca tttttatctt
    39841 tattgatggc gaaaatggtt tgcgacgcgt tagcgccaac catgtgctgg atctgcccgg
    39901 agatccccac cgccaagtac agttcaggtt tcagcatcag gttggagata ccgacatagc
    39961 gttcgtgctc catccatttt tcgttttccg ccaccggacg agaacaggcc aactccgcac
    40021 ctatcgcctt gcaaagctgt tctgccagcg caatgttctc tttgctgcca ataccgcgac
    40081 cgacgctgac caccagacgg gctttgtcga gatcgacgct gttgctctgg cgcgcctggg
    40141 ttgccgtgcg ggtaatcgcc acagccggag cctgccactc cacggtgtgc gtttcgccag
    40201 tgcgtgacgc gtctggctga gccgcatcga acgtgccgct gctgatggtc agtaccgcat
    40261 acggcgtggc aatgcgttct tcgccaatcg ccagaccacc gtaaaccatg tgtttcactg
    40321 tcgctttacc gtcctgtacg ctgacggtgc tggcatcgtt agacaccgcc gctttaaggc
    40381 gataacccag ttttgccgcc agtaatttgc cgcgacgggt gtttggcagc agcaccaggc
    40441 cgtctgcgcc gtgctggcga atagtgtcag ccatgacacc ggcgtaatct tcgatcatcc
    40501 gatcgtccgg tttgccgttt aatttccaga catgattagc gccgagctgg attgcctgtg
    40561 cgccgtcggc atcattgagg acaaaggtgt tgatttgatt agctaaagcc tgcgcaccgt
    40621 tcatcagttc cggcagacga gaaggggtat cgctgaatac ccagacttga gaaaacgtgt
    40681 tcatagcatc ccctgtaatt aaatgacttt gcgaagattt tcagcaaatg cggcgatctg
    40741 ttcttcgccg tcgccttcaa tcacgatgcg ctgacgttcg cgctgtttcg gcgcggcaac
    40801 ctgttgttct gaccaggctg cctctgcgtt aaaaccaata tccgccgccg accatacctg
    40861 gacgggcttt ttcgccgcgc cgagaatggc tttcatcgaa ggaatttgtg gggaattgat
    40921 atcagtggaa acagcaacaa ccgcaggcag cggaatgctt aaggtttcgg tttcatcttc
    40981 cagttcgcgc tcaacggtga gggtatctgc agtcagggag ataattttgc tgacgccgtt
    41041 aactgccgga atattgagga tttcgcctac cagcaaacca acctgctggg cataaaggtc
    41101 ggaagaacca tcgccacaga ggatcaaatc aaagcctgct ttctgggcgg ctgcagccag
    41161 tgcgctcgcc gtttgttgcg gcagtgcctg ctcgaactgg tcatcaatta ccacaatcag
    41221 ttcatccggg ccgcgcgata acacatcttt acgccctttg gcgttggtca gggctttacc
    41281 gcccacactt aaggctgtca cctgcgcctc tgctgcctgt tgctttagct ggcaagccgc
    41341 ttcaatagcg ttgagatcgt attggcttat tttggcatcg gctttgctga agtctaatga
    41401 accatcagca ttattgaccg caatatcctg ttcatcaggc acgcacttat agcaagtaat
    41461 aatcttcatt gcatctccag aaatcatgaa ggaaacgtcg ttcatatcgg tggtgttaat
    41521 tacagatatc acgcccttta atttggaaat aaaactttaa tcaccaatat tgaaaatgtc
    41581 acacgcagat aaatccaact ttcaatattg ttaagttcct caccaatatt gaaaacacgg
    41641 cgtagcaaaa agaaattttc aatattgttt tatggatcac caatattgaa agtcagatgt
    41701 tattttttta ctcacaatag agcataacaa actgattatt aatcaaaatt aacgaaaaaa
    41761 cgccctctat tcacccgaaa cagaaatgtg ataccaatca cagaatacag cttattgaat
    41821 acccattatg agttagccat taacgcg
//
LOCUS       DAPHKZ010000029        40286 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.029, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000029 DAPHKZ010000000
VERSION     DAPHKZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40286
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.029"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..1060)
                     /gene="bglH"
                     /locus_tag="RH288_001632"
     CDS             complement(<1..1060)
                     /gene="bglH"
                     /locus_tag="RH288_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-specific porin BglH"
                     /protein_id="HDV4030699.1"
                     /translation="MFRRNLITSAILLMAPLAFSAQSLAESLTVEQRLELLEKALRET
                     QSELKKYKDEEKKKYTPATVNRSVSTNDQGYAANPFPTSSAAKPDAVLVKNEEKNASE
                     TGSIYSSMTLKDFSKFVKDEIGFSYNGYYRSGWGTASHGSPKSWAIGSLGRFGNEYSG
                     WFDLQLKQRVYNENGKRVDAVVMMDGNVGQQYSTGWFGDNAGGENYMQFSDMYVTTKG
                     FLPFAPEADFWVGKHGAPKIEIQMLDWKTQRTDAAAGVGLENWKVGPGKIDIALVRED
                     VDDYDRSLQNKQQINTNTIDLRYKDIPLWDKATLMVSGRYVTANESASEKDNQDNNGY
                     YDWKDTWMFGTSLTQKFDK"
     gene            complement(1129..2541)
                     /gene="bglB"
                     /locus_tag="RH288_001633"
     CDS             complement(1129..2541)
                     /gene="bglB"
                     /locus_tag="RH288_001633"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglB"
                     /protein_id="HDV4030700.1"
                     /translation="MKAFPETFLWGGATAANQVEGAWQEDGKGISTSDLQPHGVMGKM
                     EPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEVEPNEAG
                     LAFYDRLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
                     QHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLLP
                     EAKIGNMLLGGLVYPLTCQPQDMLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNI
                     TIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNILNMIPNPHLKSSEWG
                     WQIDPVGLRVLLNTLWDRYQKPLFIVENGLGAKDSVEADGSIQDDYRIAYLNDHLVQV
                     NEAIADGVDIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGW
                     YAEVIKTRGLSLKKITIKAP"
     gene            complement(2560..4437)
                     /gene="bglF"
                     /locus_tag="RH288_001634"
     CDS             complement(2560..4437)
                     /gene="bglF"
                     /locus_tag="RH288_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIABC"
                     /protein_id="HDV4030701.1"
                     /translation="MTELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLK
                     KTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLDEKAQQAPENDDKGNLLNRFVY
                     VISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFFPIILG
                     YTAGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADALGLDFLGIPVTLLNYSSSVI
                     PIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPVTFLLVGPLSTWISELIAA
                     GYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLVPLCINNFTVLGYDTMIPLLMPAIM
                     AQVGAALGVFLCERDAQKKVVAGSAALTSLFGITEPAVYGVNLPRKYPFVIACISGAL
                     GATIIGYAQTKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMLH
                     FITAKRQPAQGAPQEKTPEVITPPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIA
                     ILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNV
                     GDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSII
                     R"
     gene            complement(4571..5407)
                     /gene="bglG"
                     /locus_tag="RH288_001635"
     CDS             complement(4571..5407)
                     /gene="bglG"
                     /locus_tag="RH288_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator BglG"
                     /protein_id="HDV4030702.1"
                     /translation="MNMQITKILNNNVVVVIDDQQREKVVMGRGIGFQKRAGERINSS
                     GIEKEYALSSHELNGRLSELLSHIPLEVMATCDRIISLAQERLGKLQDSIYISLTDHC
                     QFAIKRFQQNVLLPNPLLWDIQRLYPKEFQLGEEALTIIDKRLGVQLPKDEVGFIAMH
                     LVSAQMSGNMEDVAGVTQLMREMLQLIKFQFSLNYQEESLSYQRLVTHLKFLSWRILE
                     HASINDSDESLQQAVKQNYPQAWQCAERIAIFIGLQYQRKISPAEIMFLAINIERVRK
                     EH"
     gene            complement(5693..6418)
                     /gene="phoU"
                     /locus_tag="RH288_001636"
     CDS             complement(5693..6418)
                     /gene="phoU"
                     /locus_tag="RH288_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDV4030703.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVK
                     GQDFRHVGGDELDKLLAGKDSDK"
     gene            complement(6433..7206)
                     /gene="pstB"
                     /locus_tag="RH288_001637"
     CDS             complement(6433..7206)
                     /gene="pstB"
                     /locus_tag="RH288_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HDV4030704.1"
                     /translation="MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(7389..8279)
                     /gene="pstA"
                     /locus_tag="RH288_001638"
     CDS             complement(7389..8279)
                     /gene="pstA"
                     /locus_tag="RH288_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDV4030705.1"
                     /translation="MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLANALAGSGLLILWATVFGTPLGI
                     MAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPYSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKNKHG"
     gene            complement(8279..9238)
                     /gene="pstC"
                     /locus_tag="RH288_001639"
     CDS             complement(8279..9238)
                     /gene="pstC"
                     /locus_tag="RH288_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HDV4030706.1"
                     /translation="MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(9325..10365)
                     /gene="pstS"
                     /locus_tag="RH288_001640"
     CDS             complement(9325..10365)
                     /gene="pstS"
                     /locus_tag="RH288_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDV4030707.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWP
                     ITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWK
                     TNIKDSSGKPLY"
     gene            complement(10679..12508)
                     /gene="glmS"
                     /locus_tag="RH288_001641"
     CDS             complement(10679..12508)
                     /gene="glmS"
                     /locus_tag="RH288_001641"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDV4030708.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(12670..14040)
                     /gene="glmU"
                     /locus_tag="RH288_001642"
     CDS             complement(12670..14040)
                     /gene="glmU"
                     /locus_tag="RH288_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDV4030709.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPVKKK"
     gene            complement(14393..14812)
                     /gene="atpC"
                     /locus_tag="RH288_001643"
     CDS             complement(14393..14812)
                     /gene="atpC"
                     /locus_tag="RH288_001643"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDV4030710.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(14833..16215)
                     /gene="atpD"
                     /locus_tag="RH288_001644"
     CDS             complement(14833..16215)
                     /gene="atpD"
                     /locus_tag="RH288_001644"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDV4030711.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(16242..17105)
                     /gene="atpG"
                     /locus_tag="RH288_001645"
     CDS             complement(16242..17105)
                     /gene="atpG"
                     /locus_tag="RH288_001645"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDV4030712.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(17156..18697)
                     /gene="atpA"
                     /locus_tag="RH288_001646"
     CDS             complement(17156..18697)
                     /gene="atpA"
                     /locus_tag="RH288_001646"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDV4030713.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(18710..19243)
                     /gene="atpH"
                     /locus_tag="RH288_001647"
     CDS             complement(18710..19243)
                     /gene="atpH"
                     /locus_tag="RH288_001647"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDV4030714.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(19258..19728)
                     /gene="atpF"
                     /locus_tag="RH288_001648"
     CDS             complement(19258..19728)
                     /gene="atpF"
                     /locus_tag="RH288_001648"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDV4030715.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(19790..20029)
                     /gene="atpE"
                     /locus_tag="RH288_001649"
     CDS             complement(19790..20029)
                     /gene="atpE"
                     /locus_tag="RH288_001649"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HDV4030716.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(20076..20891)
                     /gene="atpB"
                     /locus_tag="RH288_001650"
     CDS             complement(20076..20891)
                     /gene="atpB"
                     /locus_tag="RH288_001650"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDV4030717.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(20900..21280)
                     /gene="atpI"
                     /locus_tag="RH288_001651"
     CDS             complement(20900..21280)
                     /gene="atpI"
                     /locus_tag="RH288_001651"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HDV4030718.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
     gene            complement(21897..22520)
                     /gene="rsmG"
                     /locus_tag="RH288_001652"
     CDS             complement(21897..22520)
                     /gene="rsmG"
                     /locus_tag="RH288_001652"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDV4030719.1"
                     /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRV
                     RFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGR
                     FYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI"
     gene            complement(22584..24473)
                     /gene="mnmG"
                     /locus_tag="RH288_001653"
     CDS             complement(22584..24473)
                     /gene="mnmG"
                     /locus_tag="RH288_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDV4030720.1"
                     /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRV
                     LYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     IGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREAS
                     GEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(24852..25295)
                     /gene="mioC"
                     /locus_tag="RH288_001654"
     CDS             complement(24852..25295)
                     /gene="mioC"
                     /locus_tag="RH288_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HDV4030721.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDL
                     PASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAI
                     DKLEAELKNFGAKQTGETLKINILDHDIPEDPAEEWLGSWINLLK"
     gene            complement(25385..25843)
                     /gene="asnC"
                     /locus_tag="RH288_001655"
     CDS             complement(25385..25843)
                     /gene="asnC"
                     /locus_tag="RH288_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HDV4030722.1"
                     /translation="MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTT
                     GHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            25995..26987
                     /gene="asnA"
                     /locus_tag="RH288_001656"
     CDS             25995..26987
                     /gene="asnA"
                     /locus_tag="RH288_001656"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDV4030723.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPF
                     LPDQIHFVHSQELLSRYPDLDAKWRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDY
                     DDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLQL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL"
     gene            complement(26992..28443)
                     /gene="viaA"
                     /locus_tag="RH288_001657"
     CDS             complement(26992..28443)
                     /gene="viaA"
                     /locus_tag="RH288_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HDV4030724.1"
                     /translation="MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKA
                     AITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRL
                     NSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
                     ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQ
                     LGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGG
                     TDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(28437..29933)
                     /gene="ravA"
                     /locus_tag="RH288_001658"
     CDS             complement(28437..29933)
                     /gene="ravA"
                     /locus_tag="RH288_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418202.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HDV4030725.1"
                     /translation="MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTS
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKE
                     IGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVD
                     LILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKT
                     ALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERSALEQWLS
                     KGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQL
                     EELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQC"
     gene            30156..32024
                     /gene="kup"
                     /locus_tag="RH288_001659"
     CDS             30156..32024
                     /gene="kup"
                     /locus_tag="RH288_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HDV4030726.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
                     GTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP
                     FFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHW
                     NKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            32191..32610
                     /gene="rbsD"
                     /locus_tag="RH288_001660"
     CDS             32191..32610
                     /gene="rbsD"
                     /locus_tag="RH288_001660"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDV4030727.1"
                     /translation="MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMAL
                     TQGVPSFMQVLGVVTNEMQVEAAIIAEEIKHHNPQLHETLLTHLEQLQKHQRNTIEIR
                     YTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF"
     gene            32618..34123
                     /gene="rbsA"
                     /locus_tag="RH288_001661"
     CDS             32618..34123
                     /gene="rbsA"
                     /locus_tag="RH288_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HDV4030728.1"
                     /translation="MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLR
                     KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            34128..35093
                     /gene="rbsC"
                     /locus_tag="RH288_001662"
     CDS             34128..35093
                     /gene="rbsC"
                     /locus_tag="RH288_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDV4030729.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTIN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
                     FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNK
                     IKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            35118..36008
                     /gene="rbsB"
                     /locus_tag="RH288_001663"
     CDS             35118..36008
                     /gene="rbsB"
                     /locus_tag="RH288_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HDV4030730.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEM
                     ALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKV
                     LKGEKVQAKYPVDLKLVVKQ"
     gene            36134..37063
                     /gene="rbsK"
                     /locus_tag="RH288_001664"
     CDS             36134..37063
                     /gene="rbsK"
                     /locus_tag="RH288_001664"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDV4030731.1"
                     /translation="MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNK
                     TIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIR
                     TVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR"
     gene            37067..38059
                     /gene="rbsR"
                     /locus_tag="RH288_001665"
     CDS             37067..38059
                     /gene="rbsR"
                     /locus_tag="RH288_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HDV4030732.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELN
                     YAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
                     SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTG
                     DFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDI
                     ELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQLTPILMERGSA"
     gene            complement(38025..39452)
                     /gene="mdtD"
                     /locus_tag="RH288_001666"
     CDS             complement(38025..39452)
                     /gene="mdtD"
                     /locus_tag="RH288_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
                     /protein_id="HDV4030733.1"
                     /translation="MSDKKKRSMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRS
                     PLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTLGSLACALSNSLPQL
                     VVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPVLGGVLVT
                     WATWHWIFLINIPIGIAGLLYARKHMPNFTTARRRFDITGFLLFGLSLVLFSSGIELF
                     GEKIVASWIALTVIVTSIGLLLLYILHARRTPNPLISLDLFKTRTFSIGIVGNIATRL
                     GTGCVPFLMPLMLQVGFGYQAFIAGCMMAPTALGSIIAKSMVTQVLRRLGYRHTLVGI
                     TVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGN
                     SVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIITVASAAMFMLL
                     KTTDGNNLIKRQRKSKPNRVPSESE"
     gene            complement(39475..40167)
                     /locus_tag="RH288_001667"
     CDS             complement(39475..40167)
                     /locus_tag="RH288_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDV4030734.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGEYEPGTILPGEIELG
                     EQFGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQSNWNFLDQELLTWWMTEENFHQ
                     VIDHFLVMRICLEPQACLLAATVGTAEQKAHLNTLMAEMAALKENFRRERWIEVDMAW
                     HEHIYEMSANPFLTSFASLFHSVYHTYFTSITSDTVIKLDLHQAIVDAIIQSDADAAF
                     KACQALLRSPDK"
BASE COUNT         9861 a        10394 c        10027 g        10004 t
ORIGIN      
        1 ctttatcaaa tttctgcgtt aaagatgtgc caaacatcca ggtatctttc cagtcataat
       61 acccgttatt atcctgatta tctttttccg atgcgctttc gtttgccgtg acataacgac
      121 cacttaccat taaggtggct ttatcccata acgggatatc tttatagcgt aaatcaatgg
      181 tattggtatt aatctgctgt ttgttttgca ggctgcgatc gtaatcatcg acatcttcgc
      241 gaaccagcgc gatatcaatt ttacccggac cgactttcca gttttccaga cctacacccg
      301 ctgcggcatc agtacgctgc gttttccagt caagcatctg gatttcaatt ttcggcgcac
      361 cgtgtttacc cacccagaaa tcagcctctg gcgcaaaggg caggaaacct ttggtggtaa
      421 cgtacatatc ggagaactgc atatagttct cgccaccggc gttatcgcca aaccagccgg
      481 tagagtactg ctgaccaacg ttaccatcca tcatcacaac ggcatcaacc cgtttgccgt
      541 tttcgttgta gacacgttgt tttaactgca aatcaaacca gccggagtat tcgttaccaa
      601 agcggcccag agaaccaatc gcccatgatt taggtgaacc atgagaggcg gtcccccaac
      661 cagaacggta atagccgttg taactaaagc caatttcatc tttcacaaat ttactgaaat
      721 ctttcagagt catggaagaa taaatcgagc ctgtctcact ggcatttttc tcttcatttt
      781 tgaccagtac agcatcaggt tttgcggcac tactggtcgg gaacggattg gcggcatacc
      841 cttgatcatt cgtacttacg ctacgattca ccgtcgctgg cgtatacttt ttcttctctt
      901 catctttata ctttttgagt tcgctttgcg tttctcttaa cgccttttct aataactcaa
      961 ggcgttgttc caccgttaat gattcagcca atgattgtgc agaaaaggct aacggtgcca
     1021 ttaataagat ggcagaggta ataagatttc gtctaaacat aatatccctt tatggtgcaa
     1081 agaaagaatt aacgcatcgc atccagactg ttctgaatgc gacgataatt aaggtgcttt
     1141 aatggttatt ttttttaatg acagcccccg cgtcttgatc acctctgcat accatccgaa
     1201 gcttttcttg cgtgttcttg tgaggcttcc ttcgccatta tcatcacgat ccacataaat
     1261 aaagccgtag cgcttagaca tttgtgaatg agatgcactg actaaatcaa ttggccccca
     1321 actggtgtac cccataatat ccacaccatc ggcaatcgct tcatttacct gtaccaggtg
     1381 atcgtttaaa taggcaattc gataatcgtc ctgtatcgaa ccatccgctt caacgctgtc
     1441 ttttgcgcct aatccgttct cgacaataaa taacggtttt tgataacgat cccaaagcgt
     1501 atttaacaga acccgtaatc caaccggatc aatttgccac ccccactctg aacttttcag
     1561 atgcggattg gggatcatat tcagtatgtt gccctgcgca tttttattaa tgctttcgtc
     1621 gtgggaaaca caaccagtca tgtaataact aaaagagatg aaatcgacgg tatgttttaa
     1681 atcttctgcg tcactttcag tcatctcaat ggtgatattg tggtcgcgga agaaacgctg
     1741 catatagccg ggatactggc cacgcgcctg aacatcacca aagaacatcc agcgccggtt
     1801 ctcttccatg gcctgcaaca tatcctgtgg ctggcaggtg agggggtaaa ccagcccacc
     1861 gagaagcata ttgccgattt tcgcttcggg gagcaggcta tgacaggctt taactgcccg
     1921 cgcactggca accagttgat ggtggatagc ctgataaact tccgcctcgc cactctcttc
     1981 tgccagcccc acgcccgtga atggcgcgtg taacgacatg ttgatttcat taaacgtcag
     2041 ccataacgcc actttatgtt ggtagcgagt aaagaccgtg cgggcgtaat gctcgaagtg
     2101 atcgatgacc gctcgattag cccaaccgcc gtagtttttc accagcccat atggcatttc
     2161 gtaatgggat aacgttacca gcggcttgat ccccgcctgc gccatttcat caaacagccg
     2221 atcgtaaaac gctaaccccg cttcattcgg ttcgacttcg tcgccctgag ggaaaattcg
     2281 cgcccaggca atggaaatac gcagacaggt gaagcccatc tcggcaaata acgcgatatc
     2341 ttccgggtaa cggtgataaa aatcgatggc gacatctttg atattctctt tccccaggat
     2401 gcgcggttcc atttttccca ttacgccatg aggctgtaaa tctgaggtcg agatcccttt
     2461 gccatcttcc tgccaggcac cttccacctg attggcagct gttgcgccac cccaaagaaa
     2521 tgtttctgga aatgctttca taattaactc cttttatcgt tagcgaatga tggataacag
     2581 cggttcacct gcgcttatct gcgccgtgcc gtggggtaat acgtccgtaa aatcatcgct
     2641 attactgatt aataccggcg tcgtcagatc aaatccggcc tcgcgaatag cagggatatc
     2701 aaaagaaatc agccgatcgc ctgtattgac cttgtcaccc acgttgacgt gagcggaaaa
     2761 gaatttgccg tccagtttta cggtgtcgat accgacatga atcaggatct ccacaccatc
     2821 atctgactca atgccaatgg cgtgtaatgt ggcgaacaac gaagcaattc gacccgcaac
     2881 cggagaacgc acttcaccaa ccgagggcag aatggcaata cctttaccca acaggccact
     2941 ggcaaacgtg gtatcagcga cgtgaatgag cggcacaatc tctcccgtca tcggtgaaca
     3001 gataccgccc tgctcaggtg gtgtaataac ctctggtgtt ttctcttgcg gggcaccctg
     3061 cgctggctga cgtttagcgg tgatgaaatg aagcatcacc gtaccgacaa atgcgcaacc
     3121 gatggcaatg acaccgccaa taacgctggc ccagacggtg aaatcaattc ccgttgacgg
     3181 gatggtttgc atgaaggtga aaatacttgg caaaccaaag gagtagactt tcgtttgcgc
     3241 gtagccaata atggtggccc ccaaagcccc actgatacag gcgataacaa aggggtactt
     3301 acgcggcagg ttgacgccat ataccgctgg ttcggtgata ccaaacagac tcgtcaacgc
     3361 cgctgatccc gccaccactt ttttctgcgc atcgcgttcg cagaggaaga cgccgagcgc
     3421 cgccccgacc tgcgccataa tggcgggcat taacagcggg atcatggtgt cgtagcccag
     3481 cacggtgaag ttattgatac acagcggcac caggccccag tgcagtccga acatgacgaa
     3541 gatttgccag aagccgccca ttaccgcgcc cgcaaatgca ggaaccgcct gataaagcca
     3601 gagataaccg gcggcaatca gttcgcttat ccaggttgat agcggcccca ccagcagaaa
     3661 ggtgacgggt gtgataacca tcagacatag caatggtgtg aagaaatttt tgattgccga
     3721 cggtaaccac gcattaagtc ggcgttccag aatgctgcac aaccaggcag aaaaaataat
     3781 gggaataacc gatgacgagt aattcaacaa tgtgaccgga atacccagga aatccagccc
     3841 cagcgcatcc gctttttgcc cgttctcgaa agcagtcaga attaatggat gcactaacgc
     3901 tccaccaatc accatggcag taaatggatt accgccgaag cgtttccccg cggtgtatcc
     3961 caggattatc gggaagaacc aaaacaaggc atcactggcg ctgaataaaa ttaaataagt
     4021 accactttgt tcggtcgtcc actgaaaagt gagcgccaga gccagcatac ctttcaagat
     4081 cccggttgcc gccatcaaac cgatcagagg cgtaaaaata cctgaaataa cataaacaaa
     4141 gcggtttagc agattacctt tatcatcatt ttccggtgcc tgttgcgctt tttcgtcaag
     4201 gcctgccaca ctgttaaccg ccaggaagac atcggccaca tggttaccta tgaccacctg
     4261 aaactggcca ccgctttcca ccaccataat aataccgggg gtctttttca gtacctctgc
     4321 ttgcgctttg ctttcatcct ttaatttaaa acgtaatcgc gttgcgcaat gcatcagact
     4381 cacaatgtta tctgcgcccc cgactcctgc gactattttt ctggctaact ccgtcataac
     4441 ttgccctcta ccgctttgcg gcaaaactcc aaaaaaaaac ctgaaaaaaa cggcctgacg
     4501 tgaatcaagc aatttttttc aggttttgcc cgcttagtgc ggtaacaatc ctttactcag
     4561 taataatatt tcagtgttct ttgcgcacgc gctctatatt tatggctaaa aacataatct
     4621 ctgcgggtga aattttacgt tgatactgca aaccaataaa aatggcgatc cgttccgcac
     4681 attgccatgc ttgcgggtaa ttttgtttta ctgcttgttg taatgattca tcactatcgt
     4741 taattgaagc atgttcaaga atacgccagg ataaaaactt cagatgtgta accagtcgct
     4801 gataactcaa gctttcttcc tggtaattaa ggctgaactg aaattttatt aattgcagca
     4861 tttcgcgcat taactgcgtg acacctgcaa catcctccat atttccgctc atttgggcac
     4921 tgaccagatg catggcaata aagcccactt catctttcgg taactgcacg cccaaccgtt
     4981 tatcaataat ggttaacgct tcttccccta gctggaactc tttcgggtaa agccgctgga
     5041 tatcccacag caacgggttg ggcagcaaca cgttttgctg aaagcgttta atcgcaaact
     5101 ggcaatggtc agttagcgag atataaatac tgtcctgtaa ttttcccaag cgctcctgcg
     5161 ctaaagagat aatacgatca caggttgcca tcacctcaag aggaatatga cttaagagtt
     5221 cgcttaatcg cccgttcagt tcatgactgc tcaaggcata ctctttttct attccacttg
     5281 agttaattct ttcgccagcg cgtttttgaa agccaattcc gcgccccatg acgacttttt
     5341 cccgctgttg atcatcaata accaccacaa cattattgtt gagaattttg gtgatttgca
     5401 tgttcatagc aaggaccttt tttataaaca aaaaaacccg acttcaccag tattctctgg
     5461 ttatgtcagg ttttgcctgc gaatgcagta acaatccagt catttattaa tggtttttat
     5521 aacgaacatc caggttcgga aattaattta attgcgtgca gagaaaatag caatgcgcta
     5581 ttgataaaaa tatgaccatg ctcgcagtta ttaactttgt gtaattttag gaatttataa
     5641 agttatatat aacaaatccc aataattaag ttattgggat ttgtctggtg aattatttgt
     5701 cgctatcttt ccccgccagc agtttatcca gctcatcgcc accgacgtga cggaaatcct
     5761 gccccttcac gtagtagaag ataaactcac aaatattctg gcagcggtcg ccaatacgtt
     5821 cgatagaacg cgcgcagaac agcgcagtaa gtacgctcgg aatggtacgc gaatcttcca
     5881 tcatgtaggt catcagttga cgaacaatac cttcgtattc ctgatcgact tttttatctt
     5941 cacgataaat acgtaccgct tcgtcaatgt ccatccgcgc gaacgcgtcc agcacgtcgt
     6001 gcagcatctg gatggtatga cggcccagcg actccagact taccagcaac ggctgatgct
     6061 gctgggagaa tttctccagc gcagtacggc agattttgtc cgccacgtcg ccaatacgct
     6121 ccagctcggc aatggtttta ctgatcacca taaccagtcg caggtcgctc gccgtcggct
     6181 gacgtttggc gataatgcgc acgcaggctt catcgatcgc cacttccatc atgttgacgt
     6241 tcttgtcgcc ttcgatgacg cgcttcgcca gatcgctgtc ctggttatgc atcgcggtga
     6301 ttgcatcaga aagctgctgc tccaccatgc cgcccatggt catcacctgc gtgcggatac
     6361 tttccagttc ggcgttgaac tggccggaaa tatgtttatt aagattgaga ctgtccataa
     6421 cgcactcctg aatcaaccgt aacgaccggt gatgtagtct tctgtttgtt tcttcgctgg
     6481 cttggtgaac agatcgtccg tgttgctgaa ctcaatcaat tcgcccaggt acataaacgc
     6541 cgtgtggtcg gaacaacgcg cagcctgctg catgttgtgg gtgacgatca ccacggtgta
     6601 atcctgcttc agttcggtga tcagctcttc aatacgcccg gtagagatag ggtcgagcgc
     6661 cgaacacggt tcgtcgagca gcagcacttc cgggcgaatg gcgataccac gcgcaataca
     6721 cagacgctgt tgctgaccac cagagagaga gtaaccgctc tggtgcaatt tatctttggt
     6781 ttcgttccac aatgcggctt tggtcaatgc ccactgcacg cgctcgtcca tgtcggcacg
     6841 ggagagcttc tcaaacagac gaacgccaaa agcgatgttg tcgtagatgg acatcggaaa
     6901 cggcgtcggt ttctggaaca ccatgcccac tttcgcacgc agcagtgcga tatcctgaga
     6961 gttggtcagg atgttgtcgc catcaagcag aatttcacct tccgcacgct gctccgggta
     7021 cagttcaaac attttgttga aggtacgcag cagcgtcgat ttaccgcagc cggacggccc
     7081 gataaacgcc gttacctggt ttttagcgat atccaggttg atgtttttca gggcatggaa
     7141 tttgccgtag tagaagttca aattacgaac ctgaatttta ctcggggcag tttcaaccat
     7201 actcattgca atcttttcct catcgtgcct gatgcacttc gctaatcagg cttaccgtag
     7261 gccggatcag gcgttcacgc cgcatccggc aaagtgttaa ccgtgtacag agtcaaaaag
     7321 gcgctcggtc ggtcccctcg cccctctggg gagagggtta gggtgagggg aaaaccgtgt
     7381 cagcaatatc aaccgtgttt attcttcgca aaaacaacgc gcgccagaat gttcagcagc
     7441 agtacgcaca gggtaatgat caataccccg gcccaggcca attgctgcca ttccgcaaac
     7501 gggctcatcg caaacttaaa gatcgtcacc ggcaggttgg cgatcggctg catcatgtcc
     7561 gtgctccaga actggttgga gagcgcggta aacagcagcg gcgcggtttc accagcaata
     7621 cgggcaatcg ccagcaggat accggtcata atcccggaca ccgacgcttt cagcgtaatc
     7681 gcagagatca tcttccactt cggtgtaccc agcgcataag ccgcttcacg caggctgtac
     7741 ggcaccagtt tcagcatgtt ctcggtggtg cggataacaa tcggcacctg caacaacgcc
     7801 agggcaatca cgcccgccca gccggagaag tgctccatct gcgccaccac aatggtgtaa
     7861 acaaacagac caaccacaat cgacggcgca gagagcagaa tgtcgttaat gaagcgaatc
     7921 acttctgcca gccaggattt acgaccatat tccgccagat aaatccccgc cataatgccc
     7981 agcggcgtac cgaataccgt ggcccacaaa attaacagcc cgctacccgc cagagcgttc
     8041 gccagaccac caccttccgt attgggcggc ggcgtcattt cagtgaacag cgccagcgac
     8101 ataccgtcga taccgcgagt gatggtggac attaaaatcc agatcagcca gaacaggccg
     8161 aaggccatcg tcgccatcga gagcgtcagc gcaatacggt ttttgaggcg gcgacgcgcc
     8221 tgcattttgc ggcgagattc agccagcgcc gcagtggttt gcatttcaac catagccatt
     8281 agcgtgcccc ctcattctta gccaggcgca taatcataaa cttcgatgcg gcgaggacga
     8341 tgaaggtaat cacaaacagg atcaggccca gttccatcag tgcggcaacg tgcagaccgg
     8401 attccgcttc cgcaaattcg ttcgccagcg cagaggtgat actgttgccc ggcatataca
     8461 gcgaggcgct gtcgagctgg taggtgttac cgatgataaa ggtcaccgcc atggtttcac
     8521 cgagcgcgcg gcccagcccc agcatgatgc cgccgataac accatttttg gtgaacggaa
     8581 gaacgatacg ccagataact tcccaggtgg tgcagccaat accgtaggcc gactctttca
     8641 tcatcaccgg ggtttgttcg aacacatcac gcattaccgc cgcaatgtac ggaataatca
     8701 tgatggcgag gatcacgcct gccgcgagga taccgatacc aaatgcgggg ccagagaaca
     8761 gcgcgccaac aatcgggata ttcgacatga tattgccgac cggctcctga aagtaaacgg
     8821 cgaacagcgg cgcaaagata aacaggcccc acatgccgta aacgatactt ggaatggctg
     8881 ccagcagctc aatggcgata cccagcgggc gtttcagcca gccaggcgca agctcagtca
     8941 ggaacagggc gataccgaaa ctcaccggga cggcgatcag cagcgcgata aacgaagtca
     9001 ccaacgtacc gtagatcggc accagcgccc cgtagatatc gttcggtgca tcccactctt
     9061 tggtccatag gaaagccaga ccaaatttct gaatgctcgg ccaggaggag atgatcagag
     9121 agacaataat gccacccaac atcaatagca caatcagcgc cgccagtttt accagcacgc
     9181 tgaaaattat gtcgcccttt ttacccggtg ggttaaaagc aggcttggtt gcagccataa
     9241 gttactcttc agttaaacgc gtttacaaag tcattttgta atgccggatg cggcgtaaaa
     9301 caccgtaccc ggcctggagt tttattagta cagcggctta ccgctactgt ctttaatatt
     9361 ggtcttccac gcagcgcgaa cctgttcaac tacactatcc ggcaggctgg cgtaatccag
     9421 gtcgttcgcc tgtttagccc cggttttgta cgcccagtcg aagaatttca gcacttctgt
     9481 gccttgttct ggtttcttct gatctttgtg gatcagaatg aacgtggtag aggtaatagg
     9541 ccatgcatct tcgcctttct ggttggtcag atcctgagcg aaggttttgc tccagtctgc
     9601 accttttgct gcattagcga agttttcttc ggtcggacta accggtttac catcagcgga
     9661 gatcagtttg gtgtacgcca ggttgttctg cttcgcgtaa gcatattcaa cataaccaat
     9721 tgcacccggc agacgctgaa cgaacgcggc gataccgtcg ttacctttac cgcccagacc
     9781 gatcggccat tttacggtag agccagtacc aacgttgttt ttccactctt cgttcacttt
     9841 cgccaggtag ctggtgaaga cgaaggaagt cccggagcca tctgcgcggc gtactacagc
     9901 aatgttttgt gaaggcagtt tcagacccgg attcagtttg gcgatggctt catcatccca
     9961 cttcttgatt ttgcccaggt agatgtcgcc gagggtttta ccatccagca ccagttcgcc
    10021 agacttcagc cctggaatgt taaccgccag caccacgccg ccaatcacgg tcgggaactg
    10081 gaacagacct tcctgagcca gtttttcgtc agacagcggc gcgtcagagg caccaaaatc
    10141 aacggtatta gcgataatct gttttacgcc accggaagaa ccgataccct ggtagttaac
    10201 tttattaccg gtttctttct ggtaagtgtc agcccatttg gcatacaccg gcgcagggaa
    10261 ggttgcacct gcacctgtca ggcttgcttc tgcaaacaca gagaaagcac tcatcgataa
    10321 ggtcgcggcg acaacagttg cgacggtggt acgcataact ttcataatgt ctcctgggag
    10381 gattcataaa gcattgtttg ttggctacga gaagcaaaat aggacaaaca ggtgacagtt
    10441 atatgtaagg aatatgacag ttttatgaca gagagataaa gtcttcagtc tgatttaaat
    10501 aagcgttgat attcagtcaa ttacaaacat taataacgaa gagatgacag aaaaattttc
    10561 attctgtgac agagaaaaag tagccgaaga tgacggtttg tcacatggag ttggcaggat
    10621 gtttgattaa aaacataaca ggaagaaaaa tgccccgctt acgcagggca tccatttatt
    10681 actcaaccgt aaccgatttt gccaggttac gcggctggtc aacgtcggtg cctttgatca
    10741 gcgcgacatg gtaagccagc agctgcagcg gaacggtgta gaagatcggt gcaatcacct
    10801 cttccacatg cggcatctcg atgatgtgca tgttatcgct acttacaaaa cccgcatcct
    10861 gatcggcgaa gacatacaac tgaccgccac gcgcgcgaac ttcttcaatg ttggatttca
    10921 gtttttccag caattcgttg ttcggtgcaa caacaataac cggcatatcg gcatcaatta
    10981 gcgccagcgg accgtgtttc agttcgccag cagcgtaggc ttcagcgtga atgtaagaga
    11041 tctctttcaa cttcaatgcg ccttccagcg cgattgggta ctgatcgcca cggcccagga
    11101 acagcgcgtg atgtttgtca gagaaatctt ctgccagcgc ttcaatgcgt ttgtcctgag
    11161 acagcatctg ctcaatacgg ctcggcagcg cctgcagacc atgcacgatg tcatgttcaa
    11221 tggaggcatc cagacctttc aggcgagaca gcttcgccac cagcatcaac agcacagtta
    11281 actgagtggt gaatgcttta gtggatgcca cgccgatttc tgtacccgcg ttggtcatta
    11341 gcgccagatc ggattcgcgc accagagaag aacccggaac gttacagatt gccagtgaac
    11401 caaggtaacc cagctctttc gacagacgca ggccagccag ggtatccgcg gtttcgccag
    11461 actgtgacaa ggtgatcatc aggctgttac gacgcacggc agatttgcga tagcggaatt
    11521 cagaggcgat ttcgacgtcg cacggaatac ctgctagcga ttcaaaccag tagcgggaaa
    11581 ccataccgga gttataagaa gtaccacagg cgaggatctg aatatgctca accttcgaca
    11641 gcagttcgtc ggcgttcggt cccagctcgc ttaaatcaac ctgaccgtgg ctgatgcgtc
    11701 cggtaagggt gtttttgatc gcgttcggct gttcgtagat ctctttctgc atgtagtgac
    11761 ggtaaatgcc tttatcgccc gcgtcatatt gcagattgga ttcgatatcc tgacgtttta
    11821 cttccgcgcc agttttatcg aagatgttta ccgaacggcg agtgatttcc gcaatatcgc
    11881 cctcttcaag gaagataaag cgacgggtca ccggcaacag cgccagctgg tcagaagcga
    11941 taaagttttc gcccatcccc aggccaatca ccagcggact accagaacgt gccgccagca
    12001 gggtatccgg gtgacgggag tccatgatca ctgtaccgta cgcaccacgc agctgcggga
    12061 tagcacgcag aacggcctca cgcagagtcc cgccttgttt cagctcccag ttcaccagat
    12121 gggcaatcac ttcggtgtcg gtttcagaaa cgaaggtata gccacgcgct tttagctctt
    12181 cacgcagcgg ttcatggttt tcgatgatgc cgttatgcac caccacaatg tgttcagaaa
    12241 catgcggatg cgcattcact tctgaaggtt caccgtgggt cgcccagcga gtgtgagcaa
    12301 taccagtgcc gccatgcaga ggatgttctt ccgctgcctg tgccagcatc tggactttac
    12361 cgaggcgacg caggcgggtc atatgacctt ctgcatcaac aacggccaga ccggcagagt
    12421 catatccgcg gtattccaga cgacgtaaac cttcaagaag gatttctgct acatcacgtt
    12481 gcgcgatcgc gccaacaatt ccacacatag tttttgattc cgatttatat cgttgtcggt
    12541 caacctgtat gcccgttttt tcgggcgccc cgagccttgt agagagtggg gttattttta
    12601 tagttactgc ttgtgggagg gagattatgt tatctcctca tcccatgtga ccgggttagc
    12661 cggccagaat cactttttct ttaccggacg acgccagcct tctttctgag tctgcggcac
    12721 acggctgata gctaatgcat tttcgccgac attacgcgtc acagttgtac ccgcagcaat
    12781 ggtcgcgcct ttgcctactg ttaccggggc caccagctga gtgtcggaac caacaaacac
    12841 atcgtcgccg ataatggtct taaatttatt cgcaccatcg tagttgcagg taatggttcc
    12901 cgcgccgatg ttaacgttat cgccaatttc cgcatcgccc aggtaagtca gatgaccagc
    12961 tttcgagcct ttacccagac gcgctttttt catctcaacg aagttaccga cgtgagcacc
    13021 ttccagcaac tcagcaccag gacgcaaacg ggcaaacggg ccaatggtac aggccgctgc
    13081 cagattcgca tcttccacaa cggtatacgg actgatttcg caatcatcgc caatcacgct
    13141 gtttttaatc acgcaaccgg tgccaatttt cacgcgatga ccgagagtca cgttgccctc
    13201 gatgataacg ttagtatcaa tttcaacatc gcgcccgtga gttagcgtac cacgcagatc
    13261 aaaacgcgct ggatcgcgca gcataacgcc tgctaacagc agtttttcag cctgttcgga
    13321 ctgataaaca cgctccagac gggagagttg caggcggtta ttcacgcctt ctacttcgct
    13381 taaacgttgc ggatgaacgg cgacgatttc acgcccttcc tgatacgcca gcgcaataat
    13441 gtcggtgatg tagtattcgc cctgagcatt attgttggtc agcttcgcca gccagcgttt
    13501 catatctgcg ccgttggcaa tcagaatgcc ggtgttgatc tcctgaatct gacgctgctc
    13561 gtcggtggca tctttgtgct caacaatgcc ggtaactttg ccgttttcac gggtgatacg
    13621 tccataaccg gtcggatcat ccagtttcac cgtcagcaga ccaatgccac cctgcggttt
    13681 agcatcacgc agacgctgga gtgtttcgac agagatcagc ggcacgtcgc cgtagagcat
    13741 taaaatgtct tcatcatcgg caaagaaagg tgcggcctgc tgcattgcat gacccgtacc
    13801 cagctgctct gcctgaagca cccagttaag gttgtcgtct ttcagcgcct gttttagcag
    13861 atcgccgccg tgaccgtaca ccaggtgaac gtgcgctgcg cctaattcat tcgcagcatc
    13921 aatgacatgc tgaaccatcg ctttcccggc aagggtatgc agcactttcg gaagatcgga
    13981 atacatgcgc gtgcctttgc ctgcggcaag gatcactacg ctcatagcat tattcaacat
    14041 acgcgtcctg actgtaattt gagaacgaat ttaaaccgct tcaccttgaa aaaactacat
    14101 ttttttcatc gtgaaatgga cagaggataa attgttcaat aacggattat ccccgctgac
    14161 gaaagcgcca ttttcgacca tcgtcacgcc ttttgtctgc agaaaattaa ggcagtacct
    14221 taatttaagc gtcaggtgga tgtttttgct cttatttcga tcaatgaata aacaggaaaa
    14281 caggggggtt ttatatcagc aggatctatg tgaacgctat tcaggacggg tcacacgcgc
    14341 aaaaaaaagc cagcctgttt ccagactggc ttttgtgctt ttcaagccgg tgttacatcg
    14401 cttttttggt caactcgata acgcgcagct gcgcgatcgc tttggccagt tccgcagacg
    14461 cctgagcgta atctacgtcg ccgtgagagc tgctaatgtg ctcttcagcc ttacgtttcg
    14521 cttccatggc tcgcgcttcg tcgagatcct ggccgcgaat tgcggtgtcg gccagaacgg
    14581 tcacgttgcc aggctgcact tcaagaatgc cgccagacag atagataaac tcttcgtgac
    14641 cgtgctgttt cacgatgcga atcataccag gcttaatggc ggtgagcagc ggtgcgtggc
    14701 cagggtagat ccccagttca ccttcgctac ccgttacctg gattttctcg accagaccag
    14761 agaacatttg ttgctctgcg ctgacgacgt ccaggtggta agtcattgcc atatcaccct
    14821 ccgattaagg cgttaaagtt ttttggcttt ttccacagct tcttcgatgg aaccgaccat
    14881 gtagaacgcc tgctccggca ggtgatcgta ttcgccttcc atgatgcctt taaagccacg
    14941 gatggtgtct ttcagggaga cgtatttacc cggagaaccg gtgaatactt ctgccacgaa
    15001 gaacggctgg gacaggaagc gctggatctt acgagcacgc gctaccacca gtttgtcttc
    15061 ttcagacagt tcatccatac ccaggatggc gatgatgtct ttcagttcct gataacgttg
    15121 caggatggac tgaacgccac gcgcggtgtc gtagtgttcc tgaccaacca ccagcgggtc
    15181 cagctgacgg ctggtggagt ccagcgggtc aacggccggg tagataccca gagacgcgat
    15241 ctgacggctc agtaccacgg ttgcgtcaag gtgcgcaaag gtggttgccg gagacgggtc
    15301 agtcaagtca tccgcaggta cgtatactgc ctgtacggag gtgatagaac cagttttggt
    15361 ggaggtgata cgttcctgca gaacgcccat ctcttccgcc agggtcggct gataacctac
    15421 cgctgaaggc atacggccca gcagtgcgga tacttccgta ccggccaggg tgtaacgata
    15481 gatgttgtca acgaacagca gaacgtcacg accttcgtca cggaatttct cagccatggt
    15541 cagaccggtc agagcaacgc gcagacggtt tcccggcggc tcgttcatct ggccatacac
    15601 cagggatact ttgtcgataa cgttggagtc ggtcatttcg tggtagaagt cgttaccctc
    15661 acgagtacgt tcacctacgc ccgcaaacac agagtaaccg gagtgctcga tcgcgatgtt
    15721 acgaatgagc tccatcatgt ttacggtttt acctacaccc gcaccaccga acagaccaac
    15781 tttaccgccc ttagcgaacg gacacatcag gtcgataact ttgataccgg tttccagcag
    15841 ttcctgagag tttgacagct cttcgtagga aggtgctgcg cggtgaatcg cccaacgctc
    15901 ttcttcaccg atctcgcctt tcatgtcgac cggttcaccc agtacgttca tgatacggcc
    15961 cagagtcgct ttacctaccg ggacttcaat cgggtgttcg aggtctttta catccagacc
    16021 gcgacgcaga ccgtcggagg aacccattgc gatggtacgt acgataccgc cgccgagctg
    16081 ctgctgaact tccagcacca gacgctcatt accattttgc acctcaagag catcgtacac
    16141 gcgcggtacg gcatcctgag ggaattcgac gtcaactacg gcgccgatta cctggacaat
    16201 ctttccagta gccatcttaa atcctctacg aaataacctg tttaaaccgc ggcggccccc
    16261 gagacgatct cggtgagttc ctgagtaatg ctggcctgac gagctttgtt gtataccaac
    16321 tgcagctctt taatcaggct gccgccattg tcggtcgcgg ctttcatcgc caccatacgg
    16381 gcggcctgct cgctggccag gttttcaacc acgccctgat aaacctgaga ttcgacataa
    16441 cgacgcagca gggtatccag caacgccttc ggatcgggtt cgtacaggta atcccaggat
    16501 ttatgtttca gatcatcatc atctgatgcc ggtaacggca gcagctggct gatggtcgga
    16561 acctgagaca tggtgttaat aaatttgttg ctgacaatgt aaagcttgtc cagacggcct
    16621 tcgtcgtagg cctgcaacat cacttttacc ggaccgatca gttcggacag ggaagggtta
    16681 tcccccatgc cggtgacctg ggcaacaaca ttgccgccca cggagttgaa gaacgacacg
    16741 cctttcgagc cgatcattgc gaggtcgcat tgaacgcctt tgtcggtcca ggtcttcatt
    16801 tccgccagca gttttttgaa caggttaatg ttcaaaccac cgcacaaacc acggtcggtc
    16861 gacaccacca ggtagcccac gcgtttaacg tcgcggtctt ccaggtaagg gtgcttatat
    16921 tccagattac cgtgtgcaag gtgaccaatc actttgcgca tggtttctgc ataaggacgg
    16981 ctggccgcca tgcgatcctg cgatttacgc attttggaag cggcgaccat ctccatcgct
    17041 ttagtgatct tttgcgtgtt ctggacgctt gcgatcttac tacgtatctc ttttgcgccg
    17101 gccatgagct tctcctcaat gccttgcggc ctgccctaag gcaagccgcc agacgttacc
    17161 aggattgggt tgctttgaag gaatcgagga tgcctttcag cttgccttcg atttcgtcgt
    17221 tgtagccacc ggtctggttg atctcttgca tcaacggagc gtgatcacgg tcgacgtaag
    17281 ccagcagagc ggcttcgaag ctgccaattt tcgacagttc aacatccgcc aggtaaccac
    17341 gttctgctgc gaacagaacc agagactgct gcgcaacgga catcggcgca tactgtttct
    17401 gtttcagcag ttcggtcact ttctgaccgt ggtcaagctg cttacgtgtt gcatcgtcaa
    17461 ggtcggatgc aaactgagag aacgctgcca gttcacgata ctgtgccaga gcggtacgga
    17521 taccaccgga cagttttttc atgatcttgg tctgtgctgc accaccaaca cgggatacgg
    17581 aaatacccgg gttaaccgca ggacgaatac cggcgttgaa caggttggtt tccaggaaga
    17641 tctgaccatc ggtaatggag attacgttgg tcggaacgaa cgcagaaacg tcacccgcct
    17701 gagtttcgat aatcggcagt gcggtcagag aaccggtttt ccctttcact tcacctttgg
    17761 tgaaggcttc aacgtattcg gcgttaacac gtgcagcacg ctccagcaga cgagagtgga
    17821 ggtagaaaac gtcgcccggg aatgcttcac gtcctggcgg acgacggagc agcagggaga
    17881 tctgacggta agcaacagcc tgtttagaca ggtcatcgta aatgatcagc gcatcttcac
    17941 cgcggtcacg gaagtattcg cccattgcgc aaccggcata cggtgccagg tattgcagtg
    18001 cagcggattc agacgcggtt gctaccacaa cgatggtgtt agccagtgcg ccgtgctctt
    18061 ccagtttacg taccacgtta gaaatggtgg acgctttctg gccgatagcg acatagatac
    18121 atttgatacc ggaatcgcgc tggttgatga tggcatcgat agccagtgcg gttttacctg
    18181 tctgacggtc accgatgatc aattcacgct gaccacgacc gattgggatc atggagtcaa
    18241 cggctttata accggtctgt accggctgat ctacggactg acgttcgata acgcccggag
    18301 cgattgcttc tacagcagag aagccgtcgt gatccagcgg acctttaccg tcgattggtg
    18361 cacccagagt gttaaccaca cggcccagca ggccacggcc aaccggaact tccaggatac
    18421 ggccagtaca cttaactttc atgccttcgg caaggtcagc gtacggaccc ataacaaccg
    18481 cacctacaga gtcgcgctcg aggttcagtg cgatagcgta acggttaccc ggcagggaga
    18541 tcatttcacc ctgcatacaa tcggccaggc cgtgaatgcg gataacaccg tcacttacag
    18601 aaacaatagt accttcgttg tgagcttcac tcacaacatt gaactgagca atgcgctgct
    18661 tgatcagttc gctgatttcg gtggaattca gttgcatgct ccagtcccct taagactgca
    18721 agacgtctgc aaggcgctca agacgaccgc gtacgctgcc atcaatgacc atatcacccg
    18781 ctcggatgat aacgcctgcc attacagact tatcgatttt gcaattcagc ttaactttgc
    18841 gtgacagacg tttttccatc gcagcagaaa ttttcgcgag ctgttgttca ctcagtgcgg
    18901 cagcggaaat gacgtctacc tcagcggtag cctcactcac ggcacgcagg tgaataaact
    18961 gctccagaac atccgggagc gcgttaagac gaccattttc agccataacc cgaatcaggt
    19021 tctgaccgtt ttcgtccagt tgctcaccac aaactgcgat aaacgactcg gcgagcgttt
    19081 ctggcgcaag cgcgccagag agaagctctg ccatttgttc gtttttggtt acctcggcgg
    19141 caaacgccag catgtcctgc cagcgttcta cactttggtg ttcgacggca aagtcaaaag
    19201 ctgctttggc gtaggggcga gctaccgtaa taaattcaga catcagcccc tccctcctta
    19261 cagttcagcg acaagtttat ccacgatgtc gctgttagca gcttcatcca cggaacgttc
    19321 gatgatcttc tcggcgccag caacagccag gatagcaact tgcttacgca gctcttcacg
    19381 ggcacgttta cgctcggctt caatttccgc ctgcgcctgg gccacgattt tagtacgttc
    19441 ctgttctgcc tcagctttcg cttcgtccag aatctgcgag cggcgtttgt tcgcctgctc
    19501 gatgattacc tgggcttccg ctttcgcttt tttcagctgg tcggtcgcgc tggcctttgc
    19561 aaggtcaagg tccttatgtg ctcgttctgc ggaagcaagg ccgtcagcaa tttctttttg
    19621 acgtttttcg atggctgcca ttaatggcgg ccatacgtac ttcatgcaga acagaacgaa
    19681 caggacaaac gcgatggcct ggccgaggat tgttgcgtta agattcacag cacaatgcct
    19741 ctatttagtt aacgttctga tattgctctt taaataaaag caacgcttac tacgcgacag
    19801 cgaacatcac gtacagaccc agacctacag cgatcatcgg gatagcatcc accagaccca
    19861 taacgataaa gaactgagta cgcagcagag gaatcagatc aggttgacgc gctgcgcctt
    19921 ccaggaattt acccccgagg atgccgatac cgatcgcagc accgattgcc gccagaccca
    19981 tcatcacagc ggcagccatg tacagcagat ccatattcag gttttccatg acagtctcca
    20041 gtttgtttca gttaaaacgt agtagtgttg gtaaattaat gttcttcaga cgccatcgac
    20101 agatagacga tcgtcagaac catgaagatg aaggcttgca gcgtaatgat caggatgtgg
    20161 aaaatggccc acggcacatt caggatccac tgtgaccacc acggcaacag accagcaatc
    20221 agaatgaaaa tcagctcacc ggcatacatg ttaccgaaca gtcgcaaacc gagtgaaact
    20281 ggtttggaca gcaggcttac cccttcaagg attaagttga caggaatgaa cgcccagtga
    20341 ttgaacggct gcagcgtcaa ctctttcgtg aagccgccga tgcctttcat tttgatgctg
    20401 tagaacagaa tcaggataaa tacgcccagt gccatagaca gcgttacgtt cacgtccgca
    20461 gacggaacca cacgcagtgc aggcagaccc agtacatgtt cagcaatgta cggcagcagg
    20521 tcgataggca gtaaatccat caggttcatc aggaataccc agacgaagat cgtcagggcc
    20581 agcggagcaa tcagcttgct tttgccatgg tacatgtctt tcacgctacc attaacaaag
    20641 ccgatcacca gctcaatcgc ggtctgaaac ttacctggca caccgctggt cgcctttttg
    20701 gctacgctac ggaataaaac caggaacaac agacccagca ccaccgagaa gaacatggag
    20761 tcaatattga ttgtccagaa ggtggctggg gggttttgtg gatccaccag cgagaatgta
    20821 cgcaggtcca gctgaaggtt attcaggtgg tgtcctatgt aatcctgcgg cgtcatattt
    20881 tctgaagcca tgatgccttt taccctttgt tgttaattac agccggtgcc agtatctgaa
    20941 ccaccagcac caaaacccac gtaacgatca gcggcaagaa taccgccttt aaaaccgcca
    21001 acgccaccac cagtaacacc aacatcgcca gaactttgaa agcttcgcca aatgcgaatg
    21061 tccaggccac ccggcctttc gctggtgtat gcgcctggtg acgccaggca aatatcataa
    21121 acaaaacgtt aggcagaaag actgccaggc ccccgcttat tgcagagacg ccccagaagg
    21181 ggtctttgag gctgaacagc aatccacttg ctatcaccac cagtaactga acgagcagaa
    21241 gcttccgagc aacgtttcga ctcacgagcg acacagacat cacgtttttc actcctgctc
    21301 ccttcgaggt atgccgcgtg tcgtataaaa ctttctttaa ggcttagagt caagcatcaa
    21361 aaagcggtca aattatacgg tgcgcccccg tgatttcaaa caataagtag ccaaaaggtg
    21421 aataaatgtt taaatatttt tccagtgcat acaattgcga cttttctgct aaccctgttc
    21481 gatcatgaaa aactgtaaat aacgcgtaaa cactggtgat aaagcgtgct tcagatcaca
    21541 tattgcgcat gttcgcgcac agcatattta tttacttggc aaatgatgcc tttgcaagtt
    21601 tatgatattt cagtctaaaa acagatactg ttttaataaa tgacatttac acaacaaaaa
    21661 ccacccattg acatttttaa taatgtttta acagccaatg atggttctta gcgccgattt
    21721 ttagcagact gatattttca ctaatgactt attttctgct taccaaaaaa agccacgtta
    21781 tcttgttgat gcaaaagagt gaacgtggcg ttaaatgtaa ccagttatat cagtagaaaa
    21841 cctggttgtt gttaacagtc taaccggtca attttttatg atttttttga taaaaattaa
    21901 attttatttg ctttaatcac caccagatga cgttcgccat ccagggctgg aacctgaagt
    21961 ttaaccactg attcgacctg atattcttcg ggcaacaaag cgatttcatc ttccggcatt
    22021 tgccctttca gcgcgtagaa acggccttgc tcaccaggaa gatggtggca ccagctcacc
    22081 atatcgttca gagaggcaaa agcgcggcta attacgccat caaatggcgg ctctgaagga
    22141 aactcttcta ccctgctctg tactggttca atattctcca gtttaagctc atgttgcacc
    22201 tgacgaagga aacgcacgcg tttaccaagg ctatccaaca gagtgaaatg ggcttcagga
    22261 cgcacgatag agagtggaat gcctggcagt cctggtccgg tgccgacatc gataaaccgt
    22321 tcaccttgca gatacggtgc caccacaatg ctatcgagaa tatggcgtac cagcatctca
    22381 ttaggatcgc ggaccgaagt caggttgtac gctttgttcc atttatgcag catattcacg
    22441 taggcaataa gctggttttt ctggtgatcg gtaagcgaaa tacctgcgtc tttcagcagt
    22501 aaggagagtt tgttgagcac ggtgattacc tgttcttgat gcgttgcctg gtaagcgggt
    22561 gcttaccagg catttttaat gcgttatgcg ctacgacgca gcataccctg ttttttcagc
    22621 cacaccagca gaatggagat ggccgcaggc gtgacgccag aaatacgcga agcttggccg
    22681 atagaggctg gtttgtgatc gttaagtttg gcgatcactt cgttagaaag accggatacc
    22741 tggcggtaat ccagtgtcgc gggtagcagg gtgttctcgt tacgcagctg cttttcgatc
    22801 tcatcttgct ggcgcgcgat ataaccttcg tatttaacct gaatctcaac ctgttccgcc
    22861 gcctgttcgt ctgtcaacgc aggggcaaac ggcgtcagcg tggttaattt ttcataagtc
    22921 atttccggac gacgcagcag atcttcacca ctggcttcac gggaaagcgg cgcagtcagg
    22981 tgagcattca cttcggctgc agcttccgcc gacggggtta cccaggtcga tttcagacgc
    23041 tgacgctcac gctcgatatt ctcaagtttc tcgttaaagc gcgcccaacg ttcgtcatcc
    23101 accaggccca gttcacgacc gatttcagtc aaacgcagat ccgcattatc ttcgcgtagc
    23161 atcagacgat attctgcgcg cgaagtaaac atacgatacg gttctttggt tcctaaagtg
    23221 cacaggtcat caactagtac gccgagatac gcctgagaac gtgccggagc ccaaccttct
    23281 ttgtcagcag acagacgggc agcgttaaga ccggccagca aaccttgcgc agcggcttct
    23341 tcgtaaccgg tagtgccgtt aatctgacca gcaaagaaca gcccctggat aaacttgctc
    23401 tccagcgtcg gtttcaggtc gcgaggatcg aagaagtcat actcaatggc ataacccgga
    23461 cgcacgatct tcgcgttttc catcccctgc atagagcgga cgatttgcat ctgcacatcg
    23521 aacggcaggc tggtggagat accgttcgga taaatttcat tagaggtcag tccttccggt
    23581 tcaaggaaga tctgatgctg atttctgtcg gcgaagcgca tgactttgtc ttcgatcgac
    23641 gggcagtagc gtgggccgac accttcgatc acccctgcgt acattgggct acgatcgagg
    23701 ttactgcgga tcacatcatg ggttttctcg ttggtatgag tgatataaca cggcacctgc
    23761 tggggatgct gggacgcatt gcccataaac gagaataccg gcattgggtt atcgccatgc
    23821 tgttgcgcca gtacgctaaa gtcgatggtt cgagcatcaa tacgcggtgg tgtcccggtt
    23881 ttcagacgac caacgcgcag cggcagttca cgcaaacggc gagaaagcgg aatggacggc
    23941 ggatcaccag cacggccacc gctgtaatta tccagaccga tatgaatttt accgtcgagg
    24001 aacgtcccaa cggtgagcac gacggctttg gcacggaact tcagtcccat ttgggtaaca
    24061 gcaccgacca cgcgatcgtt ttcgacaata agatcttcaa ccgcctgctg gaagatcatc
    24121 aggttcggtt ggttctccag cgccgtacgt accgcctgac ggtagagcac acgatccgcc
    24181 tgagctcggg tagcgcgaac cgccggtcct ttgcttgcgt ttagtatcct aaactggata
    24241 cccgcctgat cgatcgcttt cgccatcaga ccgccgagtg catccacttc ttttaccaga
    24301 tgtcccttcc caataccgcc gatcgccggg ttgcagctca tctgccccag agtgtcgata
    24361 ttgtgtgtca aaagcagagt ctgttgaccc atacgcgccg cggccatcgc ggcctcggtg
    24421 cctgcatgac ccccgccaat gatgatgacg tcaaaaggat ccggataaaa catggtgatt
    24481 gcctcgcata acgcggtatg aaaatggatt gaagcccggg ccgtggattc tactcaactt
    24541 tgtcggcttg agaaagacct gggatcctgg gtattaaaaa gaagatctat ttatttagag
    24601 atctgttcta ttgtgatctc ttattaggat cgcactgccc tgtggataac aaggatccgg
    24661 cttttaagat caacaacctg gaaaggatca ttaactgtga atgatcggtg atcctggacc
    24721 gtataagctg ggatcagaat gaggggttat acacaactca aaaactgaac aacagttgtt
    24781 ctttggataa ctaccggttg atccaagctt cctgacagag ttatccacag tagatcgcac
    24841 gatctgtata cttatttgag taaattaatc cacgatccca gccattcttc tgccggatct
    24901 tccggaatgt cgtgatcaag aatgttgatc ttcagtgttt cgcctgtctg ttttgcaccg
    24961 aaatttttga gttctgcctc gagtttatcg atagccccac aaaaggtgtc atattcacga
    25021 ctaccaatac cgattgcgcc aaagcggacc gcagaaagat cgggcttctg ttcctgcaat
    25081 gcttcataga aaggagaaag gttgtccgga atatctccgg caccgtgggt ggagctgata
    25141 accagccaga tccctgaggc aggtaaatct tctaacagcg gaccgtgcag cgtttcggtg
    25201 gtaaaacccg cctcttccag cttttcagcc aggtgttctg ctacatattc ggcaccgccg
    25261 agggtgctgc cgctgataag agtgatatct gccataaacc gccaccttta ttaagagtgg
    25321 cgtattgtac gctgtgaacg cgttgggatc tacctgtgga aaagtatggg attaaaaaag
    25381 ccgatcaggg cttgatggta cgcatgatcg ggttttgcag gacgatcaat gtctcggtgg
    25441 actgaatttc atcaattgtt tggatcttgt tgataagtac atgctggaga gcgtcgatcg
    25501 aacggcacat cacttttata aagatgctgt agtggccggt tgtgtaatag gcttcagtga
    25561 cttcatcaag gctttccagc tttgccagcg cggaagggta gtctttggcg ctctttaata
    25621 taatgccgat aaagcagcct acgtcataac cgagttgctt cgggctgaca tcaatacgcg
    25681 ccccggtaat gatccccgcc tgcttcattt tctctactcg aacgtgaatc gtccccggac
    25741 tgacgccaaa ttgtttcgcc agttcggcgt aagcggtgcg cgcattgccc attaatgctt
    25801 ccaggatgcc acggtccaga ttgtcgatca gataattttc cataggattt tcttatgcag
    25861 attgatgatt cattctattt tagccttctt ttttaatgaa tcaaaagtgt gttaggcttt
    25921 ttattgaatg attattgcat gtgtgtcggt ttttgttgct taatcataag caacaggacg
    25981 caggagtata aaaaatgaaa accgcttaca ttgccaaaca acgccaaatt agcttcgtga
    26041 aatctcactt ttctcgccaa ctggaagaac gtctggggct gatcgaagtc caggcgccga
    26101 ttcttagccg tgtgggggat ggcacgcagg ataacttgtc gggctgtgaa aaagcggtgc
    26161 aggtaaaagt gaaagctctg cctgatgccc agttcgaagt ggttcattca ctggcgaagt
    26221 ggaaacgtca gaccttaggg caacacgact tcagcgcggg cgaagggctg tacacgcaca
    26281 tgaaagccct tcgccccgat gaagaccgtc tttctccgtt gcactcggtc tatgttgacc
    26341 agtgggactg ggaacgcgta atgggcgacg gtgagcgtca attctcgact ctgaaaagca
    26401 cggtagaggc gatctgggcg ggaattaaag caaccgaagc tgcggttagc gaagagtttg
    26461 gcctggcacc gttcctgccg gatcagatcc acttcgtaca cagccaggag ttactgtctc
    26521 gttatccgga tcttgatgcc aaatggcgtg agcgggcgat agcgaaagat cttggtgcgg
    26581 tattccttgt cgggattggc ggcaagctga gcgatggtca tcgccacgac gtgcgcgcac
    26641 cggattatga tgactggagc accccgtcag agctgggcca tgcgggtctg aacggcgata
    26701 ttctggtgtg gaaccctgta ctggaagatg cgtttgagct ttcttccatg gggatccgcg
    26761 tggatgccga cacgttgaag catcagttgg cgctgaccgg tgatgaagat cgtctgcagc
    26821 tggaatggca tcaggcgctg ctgcgcggtg aaatgccgca gaccatcggc ggcggtatcg
    26881 gccagtctcg tttgaccatg ctgctgctgc aactgccgca tatcggccag gttcagtgtg
    26941 gtgtatggcc agctgctgtt cgcgagagcg tcccttctct gctgtaataa tttatcgccg
    27001 ccagcgtctg agcaggcggc ttcgcatccc ggtatcaaag cgccagatat gatcgaaaat
    27061 gcgcatgatg ccgggtttgc cgtgtgccga catcgccacg gcatgaaagc gatgctgatg
    27121 tacccgctgc agctctttca ctttactcgt cacgtcgtca ggcaaccgct gagcgataaa
    27181 atcagaaatc accaccgcat cggcatcaaa ccattccctg ctttgcaagc gttccataat
    27241 ggcgcgaaaa caactggcaa gatcggtgcc gccacgaaac tgctggctta aaaaacggat
    27301 tgcttgttcg atgccttgtg ggcctgaaag ctcataacgg acgatctcgg tggaaaatag
    27361 cataatatag cagcgccggt tttctgcgag agcaatgcgc atcaaggcca ggcagaacgc
    27421 tttcgcacac tgttcattaa agccgcccat tgagccggaa gtatccacac agacaataaa
    27481 cggcccgcgc ggctgttcat cgtaatcttt atgtaccacc ggacgttcga tcactttttc
    27541 acgccacgac tcaccgtgca ggcgataggt gagcaactgt ttttccacca gccgacggta
    27601 aaactcatac tccagttccg ttatccctag tgtcgccagt tctggcggca ggagacgtaa
    27661 aatatcatcg ctttgttgca gaccatcaac ctgctcagga accgtcgccg gttcgcgcac
    27721 catggtgcgg aaggtttcca tctgcgcatc gttgcgcggt attgatttgg cttcccgaga
    27781 acgccccagc tgctctgcca ggcgtttcag ttccggctgt tcgttaagaa attcaccgta
    27841 tttcacaatc aactgatagt cgccacgttt aagctgaccg gcgctcatat cccacagacg
    27901 accagctgca gtattgttat ctgcgagaat cggttcaagt tgtccgctca gcgtcatgcg
    27961 ttcctgaact tcactcaaca gttgttcgcg ttcttcttct aatagctgtt gatttaacgt
    28021 cgttgcttgc acgatcagac ttaaacgcca acgctggaga aaaagcgtgt gtaacgctga
    28081 agtgatcgtg ctgttagcat caaccaactg tcgggcttgt tctgcccatg gagaattcag
    28141 acgatgcagt aagtccagga tctgtggtag ctgcacaata aactgtggcg tggagaggag
    28201 ctggctttgc tgatagcaca tcacctcttc ggtgagttcc ggcgggactc gggcatcttt
    28261 cagccgactg cgcagcgctt cacgccagcg gggaacatca tcagtgattg ccgccttcag
    28321 gcgtgggaat ttttcaaaga agaccgccag ctgcggtgag gccagcagtg cgatgatcat
    28381 ctcttcgatc aatccctctt cgctgacggc cagcatcaca ttaagcgtat ccagcgttag
    28441 cattgttgtg cctggcgaat ctgtgcaccg acatcctgta ggctggcttc aatgcgacct
    28501 aaccagtcgc cagggataaa cagacatttt tgctgttcgc tgaataaagc gtgttgcttg
    28561 cgccagtcgc tttcaagctc ttccagttgt tgttttattt caccaggcag accttcagcc
    28621 gatgaaccgg gaagtgccag cgtactgcct tgtaaactta catcgcgaac gacaagatgt
    28681 tgggcgctat caacttccag attcagtttc tgggcaaagc cgataccgtt cagtttaccg
    28741 cgaatttcac cacctttgct cagccactgt tccagcgcgc tacgctcaaa ggagatatga
    28801 accacttcca tatcatgcag ttttaacggt ttttgcagca gtagagtcag agtggaagca
    28861 gtaacgttaa caggaagttg atactgctga cgacggctga aaatgccgcc cagacgaatt
    28921 accgttaagg ctgttttatc gctttgttgc tgctggagtt gcaggtgacg ttgcacaatc
    28981 gcgccaaggc gagtcaacat cccttgctgt tgccaggcgt gaccggtcat caatacatca
    29041 atttgttgtt gtatcaaatt caggctttgc gcgtcatacc acaggcaatc tttcagcaaa
    29101 atgagatcta ccggggcaac agcactgcga ccgctaaaaa aggcgctggc ctgtaataat
    29161 cggatcgctt ttttccagcg acgatccgag acataaggcg catccggtaa tttatccagt
    29221 tgctggcgca gcataaaaat cagctcaaat acatgatcgg gcagcgtaat ttcaccaatc
    29281 tctttctgcc agcgttcata ttcttcatct gtgacctgca aggcatcagg aaccggattg
    29341 tcgttttcat cctgttgact ggtcagcatg gagcggaaat tcgctttatc ctgcacttta
    29401 tctaaccaca gacgaatcag catgcggtca tataacgctt ccagactgct gtctgcttcc
    29461 ggcagctcgt tggaggccgc caccagcagg cgcatcggga ttttttctac gtgtgcaccg
    29521 ttgcggaact ggcgctcgtt aatggcggtg agcaaggtat taagaattgc cgggcccgct
    29581 ttccagatct catccagaaa gacaatttct gcttccggca ggtaaccgct ggttaaacgt
    29641 tcatagcgcc cttcatcttt tagcgcctga atagaaaggg gaccaaaaac ttcttccggc
    29701 gtggagaagc gggtcatcag atattcaaac gcgcgggcat tctgaaaggc gaattttaag
    29761 cgccgggcga tcaaactttt ggcaatacct ggcgggccaa ggaggaacac actttcacca
    29821 cttaatgccg ctaataaaca caagcggatg gcgtggctac gttcataaag ccccttttcc
    29881 aacgaactgc tcaggcggga aattctttcc gctaataaat gagggtgagc cataatgaag
    29941 tggcgtcctt tcgtcaaaag ttctgcgtaa attgcgagta tagacgtttc ttgctggtgg
    30001 ctaaaatagt ctcaaagggg gggtattttt ctttgagcca ggttaatgtg gccgcattta
    30061 ggagtacgat tttgccgtta atcgtgcata ctgtgcgctt ttttgtgggc caagggacta
    30121 agcacacatt tcatatttca acgaaagact agtctatgag cactgataat aagcaatcat
    30181 tgcccgcgat taccctcgcg gcgattggag ttgtctacgg cgatattggt accagcccgt
    30241 tatatacact tcgtgaatgt ttgtccggcc agtttggttt tggcgttgaa cgcgatgccg
    30301 tgtttggctt tttatcgctg atcttctggc tgctaatctt tgtggtttcc attaaatatc
    30361 tcaccttcgt gatgcgggca gataacgccg gtgagggggg gatcctgacg ttgatgtcgc
    30421 ttgccgggcg taatacgtcg gcgcgaacca catcaatgct ggtgattatg gggctaatcg
    30481 gcggcagctt tttctatggt gaagtcgtca taacacccgc tatttcggtg atgtcagcca
    30541 ttgaaggtct ggaaatcgtc gccccgcagc tggatacctg gatagttccc ctctcaatta
    30601 tcgttctcac tttattattt atgattcaaa agcatggcac ggctatggtc ggtaagctgt
    30661 ttgcgccgat catgctgacc tggtttttga ttctggcagg actggggtta cgtagcatta
    30721 ttgctaaccc ggaagtgctg catgcgctga atccgatgtg ggcggtgcat ttcttccttg
    30781 aatacaaaac ggtttctttt attgcattag gggcagtggt gctgtcgatt acgggggtcg
    30841 aggcgctgta tgctgatatg ggacactttg gtaagttccc tattcgtctg gcgtggttca
    30901 ctgtcgtatt accttcctta actcttaatt acttcggcca gggagcgctg ttgttaaaga
    30961 acccggaagc gattaagaac ccgttcttcc ttttggcacc ggactgggcg ctgatcccgc
    31021 tgctgatcat cgccgcactg gcgacggtaa tcgcctcgca ggcggttatc tctggcgtct
    31081 tttcattgac gcgtcaggcg gtacgtctgg gatatttgtc gccgatgcgc attattcaca
    31141 cctccgaaat ggagtcaggg caaatctata ttccgtttgt gaactggatg ctctatgtcg
    31201 cggtcgtgat tgtgattgtc agctttgagc actccagcaa cctggcggcg gcgtacggga
    31261 ttgcggtgac cggaaccatg gtgctgacgt ctattctctc gactaccgtg gcacgtcaga
    31321 actggcactg gaataagtat tttgttgcgc tgatcctgat tgctttcctt tgtgtcgata
    31381 ttccattgtt caccgctaac ctcgataaac tgctctccgg cggctggttg ccattgagcc
    31441 tcggtactgt gatgtttatc gtgatgacca cctggaagag cgagcgtttc cgcttgctgc
    31501 ggcggatgca tgaacatggt aactctctgg aagcgatgat tgcttcgctg gagaaatcac
    31561 cgcctgttcg cgtgcccggg accgcggtgt atatgtcgcg tgcaatcaac gtcattccct
    31621 ttgcgctgat gcataacctt aaacataaca aggtattgca tgagcgggtg attctgttaa
    31681 ctctgcgcac cgaagacgct ccatatgtcc ataacgtccg tcgggtacag attgaacaac
    31741 tgtcgcccac tttctggcgc gtggtggcaa gttatggttg gcgagaaacg ccaaacgtag
    31801 aagaagtttt ccaccgctgc ggtctggaag gattaagttg ccggatgatg gaaacctcct
    31861 tctttatgtc gcatgagtcg ttgatcctcg gcaaacgccc gtggtatttg cgtctgcgcg
    31921 gcaagctgta cttgctgctg caacgtaatg cgctgcgtgc accagatcaa tttgaaatcc
    31981 cgccaaacag ggttatcgaa ctgggtactc aggtcgaaat ctaacgccag acgcctcctt
    32041 tcttcataag ggggcgtttt tgttttcatg gttaatcacc atgtaaaacg tttcgaggtt
    32101 gatcacattt ccgtaacgtc acgatggttt tcccaactca gtcaggatta aactgtgggt
    32161 cagcgaaacg tttcgctgat ggagaaaaaa atgaaaaaag gcaccgttct taattctgat
    32221 atttcatcgg tgatctcccg tctgggacat accgatacgc tggtggtgtg tgatgctggt
    32281 ttacccatcc ccaaaagtac aacgcgtatc gatatggcat taacccaggg tgtaccttct
    32341 tttatgcagg tgctgggcgt cgtcacaaat gaaatgcagg tcgaggcggc cattatcgcg
    32401 gaagagatca aacaccataa tccgcaactc cacgaaacgt tgctcactca ccttgagcag
    32461 ctgcaaaaac accagagaaa taccattgaa attcgttaca ccacgcatga acaattcaaa
    32521 caacaaaccg cagaaagtca ggcggtaatt cgcagcggag aatgttctcc gtatgcgaat
    32581 atcattctct gtgctggcgt gacgttctga ggccgtcatg gaagcattac ttcagcttaa
    32641 aggcatcgat aaagccttcc cgggcgtaaa agccctctcg ggcgcagcgt taaatgtcta
    32701 tccgggccgc gtgatggcgc tggtgggcga aaacggcgcg ggtaaatcca ccatgatgaa
    32761 agtgcttact ggcatctata ctcgcgatgc cggtacgctt ttatggctgg ggaaagaaac
    32821 gacatttacc gggccaaaat cttcccagga agccgggatt gggattatcc atcaggaact
    32881 gaacctgatc ccgcagttga ccattgccga aaacattttc ctcggtcgtg agtttgttaa
    32941 tcgctttggc aaaattgact ggaaaaccat gtatgccgaa gcggataaat tgctggctaa
    33001 acttaacctg cgctttaaaa gcgacaagct ggtgggcgat ctttccatcg gtgaccagca
    33061 aatggttgaa atcgccaaag tgctgagctt tgagtcgaaa gtcatcatta tggatgaacc
    33121 gaccgatgcg ctgaccgata ccgaaaccga atccctgttc cgcgtcatcc gcgagctgaa
    33181 atcgcaaggc cgcggtattg tctatatctc ccaccgcatg aaagaaatct tcgagatttg
    33241 cgatgacgtt accgtttttc gtgatgggca atttattgct gagcgcgaag tggcatcact
    33301 gaccgaagat tcgctgattg agatgatggt gggtcgcaag ctggaagatc aatatccgca
    33361 cctggacaaa gcgccgggag atatccgcct gaaagtcgat aatctctgcg gacctggcgt
    33421 taacgatgtc tcttttactt tacgcaaagg cgaaattctt ggcgtctctg gtttgatggg
    33481 cgcaggtcgt accgaactga tgaaagtgct ctacggcgca ctaccgcgca ccagcggtta
    33541 cgtcaccctg gatgggcatg aagtcgttac ccgttcaccg caggatggcc tggcaaacgg
    33601 cattgtgtat atctccgaag accgtaaacg tgacggttta gtgttgggca tgtcagtaaa
    33661 agagaacatg tcgctgacag cgctgcgcta cttcagccgc gctggcggca gtttgaagca
    33721 tgccgatgaa cagcaggctg tgagtgattt cattcgtctg tttaatgtga aaactccgtc
    33781 gatggaacag gcaattggtc tgctttccgg tggcaatcag caaaaagtgg cgattgcccg
    33841 cggtctgatg acacgcccca aagtgttgat ccttgatgaa cctacccgtg gcgtagatgt
    33901 cggcgcgaaa aaagagatct atcaactgat taaccagttc aaagccgatg gcttgagcat
    33961 cattctggtg tcatcggaga tgccagaagt attaggcatg agcgatcgca tcatcgtcat
    34021 gcatgaaggg catctcagcg gggaatttac tcgtgagcag gccacccagg aagtgttaat
    34081 ggctgccgct gtgggcaagc ttaatcgcgt gaatcaggag taaaaaaatg acaacccaga
    34141 ctgtctctgg tcgccgttat ttcacgaaag cgtggctgat ggagcagaaa tcgcttatcg
    34201 ctctgctggt gctgatcgcg attgtctcga cgttaagccc gaactttttc accatcaata
    34261 acttattcaa tattctccag caaacctcag tgaacgccat tatggcggtc gggatgacgc
    34321 tggtgatcct gacgtcgggc atcgacttat cggtaggttc tctgttggcg ctgaccggcg
    34381 cagttgctgc atctatcgtc ggcattgaag tcaatgcgct ggtggctgtc gctgctgctc
    34441 tcgcgttagg tgccgcaatt ggtgcggtaa ccggggtgat tgtagcgaaa ggtcgcgtcc
    34501 aggcgtttat cgctacgctg gttatgatgc ttttactgcg cggcgtgacc atggtttata
    34561 ccaacggtag cccagtgaat accggcttta ctgagaacgc cgatctgttt ggctggtttg
    34621 gtattggtcg tccgctgggc gtaccgacgc cagtctggat catggggatt gtcttcctcg
    34681 cggcctggta catgctgcat cacacgcgtc tggggcgtta catctacgcg ctgggcggca
    34741 acgaagcggc aacgcgtctt tctggtatca acgtcaataa aatcaaaatc atcgtctatt
    34801 ctctttgtgg tctgctggca tcgctggccg ggatcattga agtggcgcgt ctctcctccg
    34861 cacaacccac ggcggggact ggctatgagc tggatgctat tgctgcggtg gttctgggcg
    34921 gtacgagtct ggcgggcgga aaaggtcgca ttgttgggac gttgatcggc gcattaattc
    34981 ttggcttcct taataatgga ttgaatttgt taggtgtttc ctcctattac cagatgatcg
    35041 tcaaagcggt ggtgattttg ctggcggtgc tggtagacaa caaaaagcag taataacgac
    35101 tacaggacat cttgaatatg aacatgaaaa aactggctac cctggtttcc gctgttgcgc
    35161 taagcgccac cgtcagtgcg aatgcgatgg caaaagacac catcgcgctg gtggtctcca
    35221 cgcttaacaa cccgttcttt gtatcgctga aagatggcgc gcagaaagag gcggataaac
    35281 ttggctataa cctggtggtg ctggactccc agaacaaccc ggcgaaagag ctggcgaacg
    35341 tgcaggactt aaccgttcgc ggcacaaaaa ttctgctgat taacccgacc gactccgacg
    35401 cagtgggtaa tgctgtgaag atggctaacc aggcgaacat cccggttatc actcttgacc
    35461 gccaggcaac gaaaggtgaa gtggtgagcc acattgcttc tgataacgta ctgggcggca
    35521 aaatcgctgg tgattacatc gcgaagaaag cgggtgaagg tgccaaagtt atcgagctgc
    35581 aaggcattgc tggtacatcc gcagcccgtg aacgtggcga aggcttccag caggccgttg
    35641 ctgctcacaa gtttaatgtt cttgccagcc agccagcaga ttttgatcgc actaaaggtt
    35701 tgaacgtaat gcagaacctg ttgaccgctc atccggatgt tcaggctgta ttcgcgcaga
    35761 atgatgaaat ggcgctgggc gcgctgcgcg cactgcaaac tgccggtaaa tcggatgtga
    35821 tggtcgtcgg atttgacggt acaccggatg gcgaaaaagc ggtgaatgat ggcaaactag
    35881 cagcgactat cgctcagcta cccgatcaga ttggcgcgaa aggcgtcgaa accgcagata
    35941 aagtgctgaa aggcgagaaa gttcaggcta agtatccggt tgatctgaaa ctggttgtta
    36001 agcagtagtt ttaatcaggt tgtatgacct gatggtgaca taaatacgtc atcgacagat
    36061 gaacgtgtaa tataaagaaa agcagggcac gcgccaccct aacacggtgg cgcattttat
    36121 ggacatcccg aatatgcaaa acgcaggcag cctcgttgtt cttggcagca ttaatgctga
    36181 ccacattctt aatcttcaat cttttcctac tccaggcgaa accgtaaccg gtaaccacta
    36241 tcaggttgca tttggcggca aaggcgcgaa tcaggctgtg gctgctgggc gtagcggtgc
    36301 gaatatcgcg tttattgcct gtacgggtga tgacagcatt ggtgagagcg ttcgccagca
    36361 gctcgccact gataacattg atattactcc ggtcagcgtg atcaaaggcg aatcaacagg
    36421 tgtggcgctg atttttgtta atggcgaagg tgagaatgtc atcggtattc atgccggcgc
    36481 taatgctgcc ctttccccgg cgctggtgga agcgcaacgt gagcgtattg ccaacgcgtc
    36541 agcattatta atgcagctgg aatcaccact cgaaagtgtg atggcagcgg cgaaaatcgc
    36601 ccatcaaaat aagactatcg ttgcgcttaa cccggctccg gctcgcgaac ttcctgacga
    36661 actgctggcg ctggtggaca ttattacgcc aaacgaaacg gaagcagaaa agctcaccgg
    36721 tattcgtgtt gaaaatgatg aagatgcagc gaaggcggcg caggtactgc atgaaaaagg
    36781 tatccgtact gtactgatta ctttaggaag tcgtggtgta tgggctagcg tgaatggtga
    36841 aggtcagcgc gttcctggat tccgggtgca ggctgtcgat accattgctg ccggagatac
    36901 ctttaacggt gcgttaatca cggcattgct ggaagaaaaa ccattgccag aggcgattcg
    36961 ttttgcccat gctgccgctg cgattgccgt aacacgtaaa ggcgcacaac cttccgtacc
    37021 gtggcgtgaa gagatcgacg catttttaga caggcagagg tgacgcttgg ctacaatgaa
    37081 agatgttgcc cgcctggcgg gcgtttctac ctcaacagtt tctcacgtta tcaataaaga
    37141 tcgcttcgtc agtgaagcga ttaccgccaa agttgaagcg gcgattaaag aactcaatta
    37201 cgcgccatca gctctggcgc gtagcctcaa actcaatcaa acacatacca ttggcatgtt
    37261 gatcactgcc agtaccaatc ctttctattc agaactggtg cgtggcgttg aacgcagctg
    37321 cttcgaacgc ggttatagtc tcgtcctttg caataccgaa ggcgatgaac agcggatgaa
    37381 tcgcaatctg gaaacgctga tgcaaaaacg cgttgatggc ttgctgttac tgtgcaccga
    37441 aacgcatcaa ccttcgcgtg aaatcatgca acgttatccg acagtgccta ctgtgatgat
    37501 ggactgggct ccgttcgatg gcgacagcga tcttattcag gataactcgt tgctgggcgg
    37561 agacttagca acgcaatatc tgatcgataa aggtcatacc cgtatcgcct gtattaccgg
    37621 cccgctggat aaaactccgg cgcgcctgcg gttggaaggt tatcgggcgg cgatgaaacg
    37681 tgcgggtctc aacattcctg atggctatga agtcactggt gattttgaat ttaacggcgg
    37741 gtttgacgct atgcgccaac tgctatcaca tccgctgcgt cctcaggccg tctttaccgg
    37801 aaatgacgct atggctgttg gcgtttacca ggcgttatat caggcagagt tacaggttcc
    37861 gcaggatatc gcggtgattg gctatgacga tatcgaactg gcaagcttta tgacgccacc
    37921 attaaccact atccaccaac cgaaagatga actgggggag ctggcgattg atgtactcat
    37981 ccatcggata acccagccga cccttcagca acaacgatta caacttactc cgattctgat
    38041 ggaacgcggt tcggcttaga tttacgctgt cttttgatca aattattacc atcggttgtt
    38101 ttcagaagca tgaacattgc tgctgaagca acagtaataa tgcccattgt gataaacgta
    38161 tagtggaatt gttcgacagt cgttgtgcct tccattcctt cataaacgcg aaggacggcc
    38221 gcacttacag caacgcctaa actaatcgac agttgctgcg tgaccgccag aacactgtta
    38281 ccgctgctgg cattgtcatc ggtcagatcg gcaagtgtga tggtattcat cgcggtaaac
    38341 tgcgtcgaca tagccatccc taatataaac aacggcaaga tcagcatcca tatagccatt
    38401 gctggtgatt gcaaagagaa ctgagcgatc attagcccaa taatcaccgt gatccccact
    38461 aacgtatggc gatagcccag acgacgtaag acttgggtaa ccatcgattt tgcaataatg
    38521 gaacctaacg ctgtcggtgc catcatacag ccagcaataa acgcctgata accaaatcct
    38581 acctgtaaca tcaatggcat aaggaacggt acacagccgg tccccagacg ggttgcaata
    38641 ttgcctacga taccgatcga gaaagtgcgg gttttaaata aatctaatga aattaatggg
    38701 tttggcgtgc gtcgtgcatg gagaatatag agaagcagta acccgatgct ggtgacaatt
    38761 accgtcaagg caatccagct ggcgacaatc ttttccccga atagctctat tccgcttgag
    38821 aagagaacaa ggctgaggcc aaacagcaaa aagccagtga tatcgaatct gcgtcgtgcg
    38881 gtggtgaaat tgggcatatg tttgcgcgcg taaagaaggc ccgcaatacc tatggggata
    38941 ttgattaaaa atatccagtg ccaggttgcc caggtgacca gcacgccgcc aagaacgggg
    39001 cctaaaattg gccccaccag acccggcatg gcgacaaaat tcaatactgg aagaagttca
    39061 ttacgaggat aagcgcgcag taaggccagc cgagcaacag gcatcatcat tgcgccgcct
    39121 atcccctgaa taacccggaa gacaaccagc tgtggtagcg aattagaaag tgcgcaggcc
    39181 agagaaccca atgtgaacag actcacggca agggtaaaaa tgcgacgcgt accgaagcga
    39241 tcggctagcc atccgcttac cggaataagc atcgccaccg tcagcgtata actgatgatg
    39301 gctgattgca tcgcgagagg agaacgatta aggctatgag cgattgcggg taaggcggta
    39361 ttaagaatag tggcatcaag tgcctgcatg aagaaggcca tcgccgcgat ccacggcaaa
    39421 cccgccatac tgcgcttctt tttatcgctc attcaatgtc ctgttatcgg gttatcactt
    39481 atcaggtgag cgtagcagcg cctgacaagc tttaaatgcc gcgtcggcat cgctttggat
    39541 aatcgcatcg acaatcgcct gatgcagatc cagctttatc actgtgtcgc tggtaattga
    39601 cgtgaagtaa gtgtgataaa ccgaatggaa tagcgaggcg aatgaggtca aaaacggatt
    39661 ggcgctcatt tcatagatat gctcatgcca ggccatatcg acttcgatcc agcgttcacg
    39721 gcgaaagttc tcttttaatg ccgccatttc ggccattaac gtattgagat gcgctttctg
    39781 ttccgcggtg ccaaccgttg ctgccagtag gcaggcttgc ggctccagac agatacgcat
    39841 aaccagaaag tgatcgatga cctgatgaaa gttctcttct gtcatccacc aggtaagcaa
    39901 ttcctgatca agaaaattcc agttcgattg tggcatgacc cgagtaccaa ttcgcggtcg
    39961 cggtaaaacc atcccttttg ccgttaacgt tttgaccgct tcgcgtaccg ctgtacgact
    40021 cactccaaat tgctcgccca gctcaatctc accgggcaaa atggtgccgg gttcatattc
    40081 accttttaag atccgttgcg ccagcttctc agccagaaca tacgaaaggt ttttctgtgc
    40141 agctaactgt tgtgcgctta aaggcattac ttatcttcct ttttcttttt attcctcctt
    40201 agtatgccac caggaagtgt gattacggtt gcaaaaacgg caaattgctt gttttatggc
    40261 acattaacgg ggcttttgct gaaaaa
//
LOCUS       DAPHKZ010000030        40049 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.030, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000030 DAPHKZ010000000
VERSION     DAPHKZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40049
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.030"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(47..460)
                     /gene="hns"
                     /locus_tag="RH288_001668"
     CDS             complement(47..460)
                     /gene="hns"
                     /locus_tag="RH288_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HDV4030735.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ"
     gene            1065..1682
                     /gene="tdk"
                     /locus_tag="RH288_001669"
     CDS             1065..1682
                     /gene="tdk"
                     /locus_tag="RH288_001669"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDV4030736.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQAIHCVLVDECQFLTRQQVYELSE
                     VVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
                     GRPYNEGEQVVIGGNERYVSVCRKHYKEALQVDSLTAIQERHRHD"
     gene            complement(1964..2860)
                     /locus_tag="RH288_001670"
                     /pseudo
     CDS             complement(1964..2860)
                     /locus_tag="RH288_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904641.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(2984..5659)
                     /gene="adhE"
                     /locus_tag="RH288_001671"
                     /gene_synonym="adhC"
     CDS             complement(2984..5659)
                     /gene="adhE"
                     /locus_tag="RH288_001671"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDV4030737.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQG
                     KELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLL
                     KEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA"
     gene            6136..6783
                     /gene="ychE"
                     /locus_tag="RH288_001672"
     CDS             6136..6783
                     /gene="ychE"
                     /locus_tag="RH288_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YchE"
                     /protein_id="HDV4030738.1"
                     /translation="MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARN
                     KTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
                     ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
     gene            complement(6941..7237)
                     /locus_tag="RH288_001673"
     CDS             complement(6941..7237)
                     /locus_tag="RH288_001673"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030739.1"
                     /translation="MRFLLANTFCKIVKQFSFIDRIRIYSLHPCLNKHLSIQSNRDWL
                     SMSIFSDYSSSSEMHNNLTIDYYLALSSTKGSGITNIISIILQQAQDYDVAKIT"
     gene            7521..9152
                     /gene="oppA"
                     /locus_tag="RH288_001674"
     CDS             7521..9152
                     /gene="oppA"
                     /locus_tag="RH288_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HDV4030740.1"
                     /translation="MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRN
                     NGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHL
                     RKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDL
                     GVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT
                     LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA
                     QGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYN
                     TSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH"
     gene            9238..10158
                     /gene="oppB"
                     /locus_tag="RH288_001675"
     CDS             9238..10158
                     /gene="oppB"
                     /locus_tag="RH288_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HDV4030741.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPE
                     VMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGA
                     AAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
                     LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            10173..11081
                     /gene="oppC"
                     /locus_tag="RH288_001676"
     CDS             10173..11081
                     /gene="oppC"
                     /locus_tag="RH288_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HDV4030742.1"
                     /translation="MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLI
                     VLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGR
                     ISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
                     GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNV
                     LGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA
                     GFLVVTLFCFNFIGDGLRDALDPKDR"
     gene            11093..12106
                     /gene="oppD"
                     /locus_tag="RH288_001677"
     CDS             11093..12106
                     /gene="oppD"
                     /locus_tag="RH288_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppD"
                     /protein_id="HDV4030743.1"
                     /translation="MSVIETATVPLAQQQADALLNVKDLRVTFSTPDGDVTAVNDLNF
                     SLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREILNLPEHELNKLR
                     AEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
                     RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREF
                     NTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLD
                     AEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFTPGRLRACFKPVE
                     ELL"
     gene            12103..13107
                     /gene="oppF"
                     /locus_tag="RH288_001678"
     CDS             12103..13107
                     /gene="oppF"
                     /locus_tag="RH288_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HDV4030744.1"
                     /translation="MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGHVAWLGKELLGMKPDEWRAVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGSYDEVYHNPLHPYTRALMSAVPIPDPDLE
                     KNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(13160..13489)
                     /locus_tag="RH288_001679"
     CDS             complement(13160..13489)
                     /locus_tag="RH288_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HDV4030745.1"
                     /translation="MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKL
                     CHIIWRE"
     gene            complement(13524..14984)
                     /gene="cls"
                     /locus_tag="RH288_001680"
     CDS             complement(13524..14984)
                     /gene="cls"
                     /locus_tag="RH288_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDV4030746.1"
                     /translation="MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAP
                     LFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQ
                     DDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL"
     gene            15127..15300
                     /locus_tag="RH288_001681"
     CDS             15127..15300
                     /locus_tag="RH288_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HDV4030747.1"
                     /translation="MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILN
                     KQRNSLLFAIYNI"
     gene            complement(15355..16608)
                     /gene="kch"
                     /locus_tag="RH288_001682"
     CDS             complement(15355..16608)
                     /gene="kch"
                     /locus_tag="RH288_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated potassium channel protein"
                     /protein_id="HDV4030748.1"
                     /translation="MSHWATFKQTATNLWVTLRHDILALAVFLNGLLIFKTIYGMSVN
                     LLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIY
                     TLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
                     LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMT
                     SIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLP
                     EDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKD
                     MSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLL
                     NSGHGIFSDNDELETKADSKESAQK"
     gene            complement(16908..17204)
                     /locus_tag="RH288_001683"
     CDS             complement(16908..17204)
                     /locus_tag="RH288_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HDV4030749.1"
                     /translation="MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKVF"
     gene            17428..18147
                     /gene="tonB"
                     /locus_tag="RH288_001684"
     CDS             17428..18147
                     /gene="tonB"
                     /locus_tag="RH288_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HDV4030750.1"
                     /translation="MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQP
                     ISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP
                     VKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQ
                     PQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPG
                     KPGSGIVVNILFKINGTTEIQ"
     gene            complement(18187..18585)
                     /gene="yciA"
                     /locus_tag="RH288_001685"
     CDS             complement(18187..18585)
                     /gene="yciA"
                     /locus_tag="RH288_001685"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HDV4030751.1"
                     /translation="MSTTHNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVQKGTTSVSINIEVWVKKVASE
                     PIGQRYKATEALFKYVAVDPEGKPRALPVE"
     gene            complement(18690..19229)
                     /locus_tag="RH288_001686"
     CDS             complement(18690..19229)
                     /locus_tag="RH288_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HDV4030752.1"
                     /translation="MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRF
                     RKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQ
                     RMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGIYIYRHMPQEDKS"
     gene            complement(19259..20002)
                     /locus_tag="RH288_001687"
     CDS             complement(19259..20002)
                     /locus_tag="RH288_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HDV4030753.1"
                     /translation="MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPS
                     DAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVIL
                     IIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLAL
                     APVMLVQDKMGVFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEI
                     GAVLANTLSNLISAILLIYLFRLYMLIRQ"
     gene            complement(20030..20119)
                     /locus_tag="RH288_001688"
                     /pseudo
     CDS             complement(20030..20119)
                     /locus_tag="RH288_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            20359..20997
                     /gene="ompW"
                     /locus_tag="RH288_001689"
     CDS             20359..20997
                     /gene="ompW"
                     /locus_tag="RH288_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HDV4030754.1"
                     /translation="MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGG
                     TLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAATPFRHKIGTRATGDIATVHHLPP
                     TLMAQWYFGDASSKFRPYVGAGINYTTFFDNGFNDHGKEAGLSDLSLKDSWGAAGQVG
                     VDYLINRDWLVNMSVWYMDIDTTANYKLGGAQQHDSVRLDPWVFMFSAGYRF"
     gene            complement(21057..21563)
                     /locus_tag="RH288_001690"
     CDS             complement(21057..21563)
                     /locus_tag="RH288_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HDV4030755.1"
                     /translation="MNRIEHYHDWLRDAHAMEKQAESMLESMASRIDNYPELRARIEQ
                     HLSETKNQIVQLETILDRNDISRSVIKDSMSKMAALGQSIGGIFPSDEIVKGSISGYV
                     FEQFEIACYTSLLAAAKNAGDTASIPTIEAILNEEKQMADWLIQNIPQTTEKFLIRSE
                     TDGVEAKK"
     gene            complement(21609..22109)
                     /locus_tag="RH288_001691"
     CDS             complement(21609..22109)
                     /locus_tag="RH288_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HDV4030756.1"
                     /translation="MNMKTIEDVFIHLLSDTYSAEKQLTRALAKLARATSNEKLSQAF
                     HAHLEETHGQIERIDQVVESESNLKIKRMKCVAMEGLIEEANEVIESTEKNEVRDAAL
                     IAAAQKVEHYEIASYGTLATLAEQLGYRKAAKLLKETLEEEKATDIKLTDLAINNVNK
                     KAENKA"
     gene            complement(22195..22374)
                     /locus_tag="RH288_001692"
     CDS             complement(22195..22374)
                     /locus_tag="RH288_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309858.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDV4030757.1"
                     /translation="MAEHRGGSGNFAEDREKASDAGRKGGQHSGGNFKNDPQRASEAG
                     KKGGQQSGGNKSGKS"
     gene            complement(22755..23561)
                     /gene="trpA"
                     /locus_tag="RH288_001693"
     CDS             complement(22755..23561)
                     /gene="trpA"
                     /locus_tag="RH288_001693"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HDV4030758.1"
                     /translation="MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAG
                     ADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMY
                     ANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADD
                     DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPD
                     QVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS"
     gene            complement(23561..24754)
                     /gene="trpB"
                     /locus_tag="RH288_001694"
     CDS             complement(23561..24754)
                     /gene="trpB"
                     /locus_tag="RH288_001694"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HDV4030759.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQ
                     FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMD
                     KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE
                     REGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALE
                     AFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            complement(24766..26127)
                     /gene="trpCF"
                     /locus_tag="RH288_001695"
     CDS             complement(24766..26127)
                     /gene="trpCF"
                     /locus_tag="RH288_001695"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415778.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HDV4030760.1"
                     /translation="MMQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDAL
                     QGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFNFLP
                     IVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMG
                     VLTEVSNEEEQERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGI
                     NTYAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAG
                     AIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQL
                     HGNEEQLYIDTLREALPAHVAIWKALSVGETLPAREFQHVDKYVLDNGQGGSGQRFDW
                     SLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTL
                     RAY"
     gene            complement(26128..27723)
                     /gene="trpD"
                     /locus_tag="RH288_001696"
     CDS             complement(26128..27723)
                     /gene="trpD"
                     /locus_tag="RH288_001696"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HDV4030761.1"
                     /translation="MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERL
                     ATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPANTLQPILEKLYQAQTLSQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANA
                     QTVLEVLRSGSAYDRVTALAARG"
     gene            complement(27723..29285)
                     /gene="trpE"
                     /locus_tag="RH288_001697"
     CDS             complement(27723..29285)
                     /gene="trpE"
                     /locus_tag="RH288_001697"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HDV4030762.1"
                     /translation="MQTQKPTLELLTCEGAYRDNPTALFHQLCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSGNGEALLALLDNALPAGVESEQSPNCRV
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLFSYDLVAGFED
                     LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAPNEEEKQRLTARLNELRQQ
                     LTEAAPPLPVVSVPHMRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGR
                     RADGSLDRDLDSRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGVVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     misc_feature    complement(29307..29400)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            complement(29377..29421)
                     /gene="trpL"
                     /locus_tag="RH288_001698"
     CDS             complement(29377..29421)
                     /gene="trpL"
                     /locus_tag="RH288_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HDV4030763.1"
                     /translation="MKAIFVLKGWWRTS"
     gene            29559..30440
                     /gene="yciV"
                     /locus_tag="RH288_001699"
     CDS             29559..30440
                     /gene="yciV"
                     /locus_tag="RH288_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HDV4030764.1"
                     /translation="MSDTNYAVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITD
                     HDTTAAIAPAREEISRSGLALNLIPGVEISTVWENHEIHIVGLNIDITHPLMCEFLAQ
                     QTERRNQRAQLIAERLEKAQIPGALEGAQRLAQGGAVTRGHFARFLVECGKASSMADV
                     FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAE
                     HHGDAMEVAQCQQSPNERTQLAALARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVE
                     GVWQLWEQPQNTTEREL"
     gene            30437..31057
                     /locus_tag="RH288_001700"
     CDS             30437..31057
                     /locus_tag="RH288_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDV4030765.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKI
                     EDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL"
     gene            31085..32980
                     /locus_tag="RH288_001701"
     CDS             31085..32980
                     /locus_tag="RH288_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HDV4030766.1"
                     /translation="MAGKFRCILLLIAGLFVSSLSYAENTEIPSYEEGISLFDVEATL
                     QPDGVLDIKENIHFQARNQQIKHGFYRDLPRLWMQPDGDAALLNYHIVGVTRDGIPEP
                     WHLDWHIGLMSIVVGDKQRFLPQGDYHYQIHYQVKNAFLREGDSDLLIWNVTGNHWPF
                     EIYKTRFSLQFSNIAGNPFSEIDLFTGEEGDTYRNGRILEDGRIESRDPFYREDFTVL
                     YRWPHALLSNASAPQTTNIFSHLLLPSTSSLLIWFPCLFLVCGWLYLWKRRPQFTPVD
                     VIETDVIPPDYTPGMLRLDAKLVYDDKGFCADIVNLIVKGKIHLEDQSDKNQQILIRV
                     NEGATRNNAVLLPAEQLLLEALFRKGDKVVLTGRRNRVLRRAFLRMQKFYLPRKKSSF
                     YRSDTFLQWGGLAILAVILYGNLSPVGWAGMSLVGDMFIMICWIIPFLFCSLELLFAR
                     DDDKPCVNRVIITLFLPLICSGVAFYSLYINVGDVFFYWYMPAGYFTAVCLTGYLTGM
                     GYIFLPKFTQTGQQRYAHGEAIVNYLARKEAATHSGRRRKGETRKLDYALLGWAISAN
                     LGREWALRIAPSLSSAIRAPEIARNGVLFSLQTHLSCGANTSLLGRSYSGGGAGGGAG
                     GGGGGGW"
     gene            33191..34066
                     /gene="rluB"
                     /locus_tag="RH288_001702"
     CDS             33191..34066
                     /gene="rluB"
                     /locus_tag="RH288_001702"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HDV4030767.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEV
                     TPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QVSGGRRSGGRNNNG"
     gene            complement(34106..34696)
                     /gene="cobO"
                     /locus_tag="RH288_001703"
     CDS             complement(34106..34696)
                     /gene="cobO"
                     /locus_tag="RH288_001703"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HDV4030768.1"
                     /translation="MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTA
                     AFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDT
                     AACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
                     RGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY"
     gene            complement(34693..35451)
                     /locus_tag="RH288_001704"
     CDS             complement(34693..35451)
                     /locus_tag="RH288_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HDV4030769.1"
                     /translation="MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGR
                     NEEKLRQVASHINEETGRQPQWFILDLLTCTSENCQQLAQRIAVNYPRLDGVLHNAGL
                     LGDVCPMSEQNPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPA
                     DIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGISQ"
     gene            35671..36720
                     /gene="sohB"
                     /locus_tag="RH288_001705"
     CDS             35671..36720
                     /gene="sohB"
                     /locus_tag="RH288_001705"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HDV4030770.1"
                     /translation="MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRV
                     NNLSEQYKEMKEELAAALMDSHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVATDSKPR
                     VWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
                     LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKD
                     IDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVAT
                     GEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESAD
                     RLLLRWWQRGQKPLM"
     gene            complement(36756..37007)
                     /locus_tag="RH288_001706"
     CDS             complement(36756..37007)
                     /locus_tag="RH288_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HDV4030771.1"
                     /translation="MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLV
                     FTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            37387..39984
                     /gene="topA"
                     /locus_tag="RH288_001707"
     CDS             37387..39984
                     /gene="topA"
                     /locus_tag="RH288_001707"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDV4030772.1"
                     /translation="MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPT
                     TSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRIL
                     PAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDH
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     PPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYV
                     DGKWVEGKK"
BASE COUNT        10143 a         9573 c        10129 g        10204 t
ORIGIN      
        1 aatcccgccg ctggcgggat tttaagcaag tgcaatctac aaaagattat tgcttgatca
       61 ggaaatcgtc gagggattta ccttgctcat ccattgcttt tttgattaca gctggagtac
      121 ggccttggcc agtccaggtt ttagtttcgc cgttttcgtc aacgtagcta tattttgccg
      181 gacgctgagc acgtttagct ttggtgccag atttaacggc agcaaggcta ttcagcagtt
      241 cgttcgggtc aataccgtca gcgatcagca tttcgcgata ttgctgcagt ttacgagtgc
      301 gctcttcaac ttcagcagca gccgcgcttt cttcttcgcg acgttcgtta acaacaactt
      361 ctaatttttc cagcatttct tccagcgttt caagtgtaca ttctcttgcc tgcgcacgaa
      421 gagtacggat gttgttcaga attttaagtg cttcgctcat tgtagtaatc tcaaacttat
      481 attggggtgg tttgttgagg taataataga gccttaaatt cagttgtgca atagccagga
      541 atgtaaggaa ttcaaaattg ttctttattt tgtgccgcca ataaatatct tttcataaaa
      601 ttagccagaa aagacgcggc atatagccct atttacaccg atgatttcgc agcacgtgag
      661 gttaaaactt cctgattcat gtcacatttt atggggagat tatcgtaggc tgacgacctt
      721 tcagtcttct gtattagttg tgtttacgag aattccctat taagcgaatg atgaaaagta
      781 gaacagtcgc aataagagca tggacttagt attgcactat ctcctggagg tcaacagagg
      841 gctattactt gcgcaacagg ttaaagattg tgaatagtta ccagcagtca tttacccgct
      901 tataacaagc gaggcagttg taatgatagc tcagaaggat tatgcaaggc ttcgtaaggg
      961 agaacgcata tacccacttc tgtgcatact gttgagctga aaaactgacg aattatgata
     1021 aactccagcc aactttattt catatcattg agggcctgtg gctgatggca cagctatatt
     1081 tctactattc cgcaatgaat gcgggtaagt ctacagcatt gttgcaatct tcatacaatt
     1141 accaggaacg cggcatgcgc actgtcgtat atacggcaga aattgatgat cgctttggtg
     1201 ccgggaaagt cagttcgcgt ataggtttgt catcgcctgc aaaattattt aaccaaaatt
     1261 catcattatt tgatgagatt cgtgcggaac atgaacagca ggcaattcat tgcgtactgg
     1321 ttgatgaatg ccagttttta accagacaac aagtatatga attatcggag gttgtcgatc
     1381 aactcgatat acccgtactt tgttatggtt tacgtaccga ttttcgaggt gaattattta
     1441 ttggcagcca atacttactg gcatggtccg acaaactggt tgaattaaaa accatctgtt
     1501 tttgtggccg taaagcaagc atggtgctgc gtcttgatca agcaggcaga ccttataacg
     1561 aaggtgagca ggtggtaatt ggtggtaatg aacgatacgt ttctgtatgc cgtaaacact
     1621 ataaagaggc gttacaagtc gactcattaa cggctattca ggaaaggcat cgccacgatt
     1681 aataagaatt tctttactga cagggtgagc agggcacttt tatcctgtca gttcgtttta
     1741 cgcacttctt ccgggctata tacccttctc ggcagttttt taacgccgct atacgcctca
     1801 cagggctctt aagcaccgac gttgacttgt gacctgtaaa gtacaatatc cctgtgttta
     1861 ggcgttatac atcgtcgcaa atatgatgaa ggctaatgct gtcggtttat ggaaaagttg
     1921 ctttgggtaa acaaaaaata cggccccaga agggcaatgc cgttcactta agaggagcgg
     1981 cactatgttt cacaggataa cgggtttttg atatcttaac cgacctcggc cttgatggtc
     2041 gggggcgttt tgttatgaac accacttcca gagcaccccg aagatgctcc agtcgtttcg
     2101 ggatggtccc tggtgacgcc gtgtttccca gctctatcat ttctgatgcg atattcttcc
     2161 acgcaggcag tagccagtgg cggttacaac ccttctggtt cagcgtcagc agcaggtctt
     2221 cgctgtaaaa aagtttatca aacaacgtaa tagagttatc cgggatggtg gcgagcatgg
     2281 agtgggccag cacagtttcg ctctgccggt aaggtgcggt cacggcattc agcagaatgt
     2341 gacttcccag gttcattaag gccaccagac gcataaccgg gtaggcgttc tgccgcttag
     2401 tggatgtgtt ggcagaccca taatattcac gcagctcggg tttatcaggt gtcctgaact
     2461 gtgcgccatc aatggcaaaa agttgcaggc cgtgccagtc atccttcagg taacgttccg
     2521 cgcccctgtc tgtgcggtct ggcggaagag ccattccact ggggcggccc ccacgcgctg
     2581 acgcgcctgg gtgacagcgc tgcgggccag caggttcatc cccgcttcgc catccgcgct
     2641 caggttcaga cggcgaacaa catcggtaat tggctcattg caccaccatc cagataacca
     2701 tgtcccccgg taaacgacgg cggcgaacgg tcgcatgagc agaaagcgtc aggcagtgtt
     2761 gtatccactc ggtgggaagg tgttctgcaa atagttgtgc agagggcgga ggcataagcg
     2821 gatggtcact gaaatcgagc agatcattga gaagtggcat aagaaaacgg ctccctgttg
     2881 tggaagccgt tatagtgcct cagtttaagg atcggtcaac taatccttaa ctgatcggca
     2941 ttgcccagaa ggggccgttt atgttgccag acagcgctac tgattaagcg gattttttcg
     3001 cttttttctc agctttagcc ggagcagctt ctttcttcgc tgcagtttca ccttctacat
     3061 aatcacgacc gtagtaggta tccagcagaa tctgtttcag ctcggagatc agcgggtaac
     3121 gcgggttagc gccggtgcac tggtcatcga atgcatcttc agacagttta tccacgttcg
     3181 ccaggaagtc tgcttcctga acgccagctt cacggataga tttcggaata cccagttcag
     3241 ctttcagcgt ttccagccat gccagcagtt tctcgatctt agcagcagta cggtcgcccg
     3301 gtgcgctcag acccaagtgg tcggcaattt cagcataacg acggcgagcc tgcggacggt
     3361 catactggct gaatgcagtc tgcttggtcg ggttgtcgtt cgcattgtag cgaataacgt
     3421 tacaaatcag cagggcgttt gccagaccgt gcggaatatg gaactgggaa cccagtttgt
     3481 gcgccattga gtgacataca cccaggaagg cgttcgcaaa cgcgataccc gcgatagtcg
     3541 ctgcactgtg aacacgttca cgcgctaccg gatttttaga cccttcgtgg taggacgctg
     3601 gcagatattc tttcagcagt ttcagtgcct gcagagcctg accatcagag aactcagatg
     3661 ccagtacaga aacataagct tccatggcgt gagttactgc gtccagacca ccgaaagcac
     3721 acagggactt cggcatgtcc ataaccaggt tggcgtcgac aatcgccata tccggagtca
     3781 gcgcatagtc tgccagcgga tatttctgac cagtagcgtc gtcagttaca accgcaaacg
     3841 gagtgacttc agaacctgta ccagaagtgg tggtgacagc gatcattttc gctttcacgc
     3901 ccattttcgg gaacttgtag atacgtttac ggatatccat aaagcgcagc gccagctctt
     3961 cgaagtgagt ttccggatgt tcgtacataa cccacatgat cttcgcggcg tccatcgggg
     4021 aaccaccacc cagcgcgata atcacgtctg gtttgaagga gtttgccagt tctgcacctt
     4081 tacgaacgat gctcagggtc gggtccgctt ctacttcgaa gaagacttca gtttcaacgc
     4141 ctgctgcttt cagtacggaa gtgatctgat cagcataacc attgttgaac aggaagcggt
     4201 cagtcacgat gagcgcacgt ttgtggccat cagtaatcac ttcatccagc gcgattggca
     4261 gggagccacg gcggaagtag atagatttcg gaagtttgtg ccacaacatg ttttcagctc
     4321 gcttagcaac ggttttcttg ttgatcaggt gtttcggacc aacgttttca gagatggagt
     4381 taccacccca agaaccacaa cccagagtca gggaaggtgc gagtttgaag ttatacaggt
     4441 caccgatacc accctgagac gctggggtgt taatcaggat acgcgccgtt ttcattttct
     4501 gaccgaagta agaaacgcga gccggttggt tatcctggtc agtgtacagg caagaggtat
     4561 gaccgatacc gcccatagca accagtttct ctgctttttc taccgcgtct tcgaaatctt
     4621 tagcgcggta cattgccaga gtcggggaca gtttttcatg tgcgaacggt tcgctttcat
     4681 caacaacggt cacttcaccg atcagaatct tggtgttttc tggtacagag aagcctgcca
     4741 gttcagcaat tttataggct ggctgaccaa cgatagccgc gttcagcgca ccgtttttca
     4801 ggataacatc ctgaacagct ttcagctctt taccctgcaa cagatagccg ccgtgggttg
     4861 caaaacgttc acgtacagcg tcataaacag agtcaacaac aacaacagac tgttcagaag
     4921 cacagattac gccgttgtcg aaggttttgg acatcagtac agatgcaact gcacgtttga
     4981 tatcagcagt ttcatcgata acaactggag tgttgcccgc gcctacaccg atagctggtt
     5041 taccggagct gtatgcggct ttaaccatgc ccggaccacc agtcgcgagg atcaggttga
     5101 tgtctgggtg gtgcatcagt gcgttagaca gttcaacaga aggttgatcg atccagccga
     5161 tcagatcttt cggagcaccg gcagcgatag cagcctgcag aacgatatca gccgctttgt
     5221 tggtggcatc ttttgcacgc gggtgcgggg agaagataat ggcgttacgg gtcttcagac
     5281 tgatcagcga tttgaagata gcagttgaag tcgggttagt ggtcggaacg ataccgcaaa
     5341 taataccgat tggttcagcg atagtgatgg taccaaaagt gtcgtcttca gacagaacac
     5401 cacaggtttt ttcatcttta taggcgttgt agatatattc agaagcaaag tggtttttga
     5461 tcactttatc ttcgacgata cccatgccgg attcggcaac ggccattttc gcgagtggga
     5521 ttcgagcatc tgcagcagcc agagcggcgg cgcggaagat tttgtctact tgctcttgag
     5581 tgaaactggc atattcacgc tgggcttttt ttacacgctc tacgagtgcg ttaagttcag
     5641 cgacattagt aacagccata atgctctcct gataatgtta aactttttta gtaaatcatc
     5701 tgctcgaata cgagagtata gtcagtgcgg tgatgatttg cttaacctat gaaaatcaaa
     5761 agcttactcg cgctcacact cactgtgatt tactaaaaga gtttaaacat tagagttatt
     5821 atctctaatg cgtcacttcc aggtggcgta agcaagatta ctcacttctg ggtactgatt
     5881 acgtgatcca aatcaaattt ttgcaaagct gacacctttc agcatcgctt ttcgccatta
     5941 tagctaacag ttaataaatt gtagtatgat ttggtggcta cattagcatg ttttgcacaa
     6001 ctagataaca ataacgaatg atagcaattt taagtagtta ggaggtgaaa aatgctgtca
     6061 aaaggcgtat tgtcagcgcg tcttttcaac cttatttatg gctaacatta tccggctttt
     6121 gcttcggagc taaccgtgat tcagaccttt tttgattttc ccgtttactt caaatttttc
     6181 atcgggttat ttgcgctggt caacccggta gggattattc ccgtctttat cagcatgacc
     6241 agttatcaga cagcggcagc gcgaaacaaa actaacctta cagccaacct gtctgtggcc
     6301 attatcttgt ggatctcgct ttttctcggc gacacgattc tacaactttt tggtatatca
     6361 attgattcgt tccgtatcgc cgggggtatc ctggtggtga caatagcgat gtcgatgatc
     6421 agcggcaagc ttggcgagga taaacagaac aagcaagaaa aatcagaaac cgcggtacgt
     6481 gaaagcattg gtgtggtgcc actggcgttg ccgttgatgg cggggccagg ggcgatcagt
     6541 tctaccatcg tctggggtac gcgttatcac agcattagct atctgtttgg tttctttgtg
     6601 gctattgcat tgttcgcttt atgttgttgg ggattgttcc gcatggcacc gtggctggta
     6661 cgggttttac gccagaccgg catcaacgtg attacgcgta ttatggggct attgctgatg
     6721 gcattgggga ttgaatttat cgttactggt attaagggga ttttccccgg cctgcttaat
     6781 taattccttt caaatgaaac ggagctgcca tgctccgttt acttcgtcat tatttttact
     6841 ttgttcccgc gcagttatca aaagcaaaag gaataggtaa aaatattctt ctcaaattac
     6901 agttagttat aaggatttcc ttaactgctt ctcctcacca tcatgttatt ttcgccacat
     6961 cataatcctg ggcttgctga agaataattg aaatgatatt agtaattcca ctgcctttgg
     7021 tagaggaaag tgctaaataa taatcaattg ttaaattatt gtgcatttca ctactggaac
     7081 tgtaatcaga aaagatagac atgcttagcc aatctctatt tgattgaatt gaaagatgtt
     7141 tgttaaggca tggatgcaag ctatagattc tgatacggtc aataaaagag aattgcttaa
     7201 caattttgca aaatgtattg gcgagtaaga accgcatttg gtactttccg ggcaaccgcc
     7261 agacgattct ttattggtaa tgagaataat taacaattaa agagcgtcgc gaaagaataa
     7321 tgtgtctcga caggggagac acagtacgaa tcgacataag gtgatcgtct gaatcaccag
     7381 aataaataaa gtcggtgata gtaatacgta acgataaagt aacctgacag cagaaagtct
     7441 ccgagcctgt gcagggtccc aatccgggat tacacatgct ggttaatacc agtaattata
     7501 atgagggagt ccaaaaaaca atgaccaaca tcaccaagag aagtttagta gcagctggcg
     7561 ttctggctgc gctaatggca gggaatgtcg cgctggcagc tgatgtaccc gcaggcgtca
     7621 cactggcgga aaaacaaaca ctggtacgta acaatggttc agaagttcag tcattagatc
     7681 cgcacaaaat tgaaggtgtt ccggagtcta atatcagccg agacctgttt gaaggcttac
     7741 tggtcagcga tcttgacggt catccagcac ctggcgtcgc tgaatcctgg gataataaag
     7801 acgcgaaagt ctggaccttc catttgcgta aagatgcgaa atggtctgat ggcacgccag
     7861 tcacagcaca agactttgtg tatagctggc aacgttctgt tgatccgaac actgcttctc
     7921 cgtatgccag ttatctgcaa tatgggcata tcgccggtat tgatgaaatt cttgaaggga
     7981 aaaaaccgat taccgatctc ggcgtgaaag ctattgatga tcacacatta gaagtcacct
     8041 taagtgaacc cgttccgtac ttctataaat tacttgttca cccatcaact tcaccggtgc
     8101 caaaagccgc tatcgagaaa ttcggcgaaa aatggaccca gcctggtaat atcgtcacca
     8161 acggtgccta taccttaaaa gattgggtcg taaacgaacg aatcgttctt gaacgcagcc
     8221 cgacctactg gaacaacgcg aaaaccgtta ttaaccaggt aacctatttg cctattgctt
     8281 ctgaagttac cgatgtcaac cgctaccgta gtggtgaaat cgacatgacg tataacaaca
     8341 tgccgatcga attgttccag aagctgaaaa aagagatccc ggacgaagtt cacgttgatc
     8401 catacctgtg cacttactat tacgaaatta acaaccagaa accgccattc aacgatgtgc
     8461 gtgtgcgtac cgcactgaaa ctaggtatgg accgcgatat cattgttaat aaagtgaaag
     8521 cgcagggcga catgcccgcc tatggttaca ctccaccgta tactgatggc gcaaaattga
     8581 ctcagccaga atggtttggc tggagccagg aaaaacgtaa cgaagaagcg aaaaaactgc
     8641 tggctgaagc gggttatacc gcagacaaac cgttgaccat caacctgctg tataacacct
     8701 ccgatctgca taaaaagctg gcgattgctg cctcttcatt gtggaagaaa aacattggtg
     8761 taaacgtcaa actggttaac caggagtgga aaacgttcct cgacacccgt caccagggta
     8821 cttttgatgt ggcccgtgca ggctggtgtg ctgactacaa cgaaccaact tccttcctga
     8881 acaccatgct ttcgaacagc tcgatgaata ccgcgcatta taagagcccg gcctttgaca
     8941 gcattatggc ggaaacgctg aaagtgactg acgaggcgca gcgcacagct ctgtacacta
     9001 aagcagaaca acagctggat aaggattcgg ccattgttcc tgtttattac tacgtgaatg
     9061 cgcgtctggt gaaaccgtgg gttggtggct ataccggcaa agatccgctg gataatacct
     9121 atacccggaa tatgtacatt gtgaagcact aatggcaatg cgtggggcag gagtgtcctg
     9181 ctccacggtg tctgattttt atcgcattac agaaggcaca ggccagaagg tagggcaatg
     9241 ttaaaattta ttctacgtcg ctgtctggaa gcgattccga cgctatttat tcttattact
     9301 atttcgttct ttatgatgcg cctcgcgccg ggaagccctt ttaccggcga acgtacttta
     9361 ccgccagaag tgatggccaa tatcgaagcg aaatatcatc ttaatgatcc gatcatgaca
     9421 cagtatttca gctacctgaa acaactggcg cacggtgatt tcggtccatc gtttaaatat
     9481 aaagattatt cggtcaatga cctggttgca tccagttttc ccgtttctgc caaattggga
     9541 gccgcagcat ttttccttgc ggtaatactg ggtgttagtg ctggcgttat tgccgcatta
     9601 aaacaaaaca ccaaatggga ctataccgtg atgggcctgg caatgaccgg ggttgttatc
     9661 cccagttttg tggttgcacc attattagtc atgatatttg cgatcatttt gcattggctg
     9721 ccgggcggtg gctggaatgg tggggcgctt aaattcatga tattgccgat ggtggcgttg
     9781 tcactcgctt atatcgccag tattgcgcgt attacccgtg gctctatgat tgaagtatta
     9841 cactccaact ttattcgtac tgcccgggcg aaagggttac ctatgcggcg gatcatttta
     9901 cgccacgcat taaaacctgc tctgttaccc gtgctctcct atatgggccc cgcatttgtc
     9961 ggcattatta ccggttctat ggtcatcgaa accatttatg gtttgccggg gattgggcaa
    10021 ctgttcgtta atggcgcatt gaaccgtgac tattccttag tgttaagcct gaccatcctg
    10081 gttggtgcgt taaccatttt gtttaatgcc attgtcgatg tgctatatgc ggttatcgac
    10141 ccgaaaatcc gttactgata ctggagctcg cgatgatgtt aagtaagaaa aacagcgaga
    10201 cgctggaaaa tttcagtgaa aagctggagg tcgaagggcg cagcttgtgg caggacgcac
    10261 gtcgacgttt tatgcataac cgtgcggcgg ttgccagtct gatagtgctg gtgctgatcg
    10321 cgttatttgt aatcctggca ccgatgcttt cgcagtttgc ctatgacgat actgactggg
    10381 cgatgatgtc cagcgccccg gatatggagt ccggtcacta ctttggtact gactcatccg
    10441 gtcgcgacct gcttgtgcgc gttgcgattg gcgggcgtat ctcactcatg gtcggtgttg
    10501 ctgcggcact ggtggcagtg gtcgtgggga cactttatgg ttcgctttcc ggttatctgg
    10561 gcggtaaagt ggattcggta atgatgcgtc tgctggaaat cctcaactcc ttcccattca
    10621 tgttcttcgt cattttgctt gtgacctttt tcggtcaaaa catcctgctg attttcgtgg
    10681 cgattggcat ggtttcctgg ctggatatgg ctcgtattgt gcgtggacaa accctgagtc
    10741 tgaagcgcaa agagtttatt gaggcggcac aagttggcgg tgtatcgaca tcgggcattg
    10801 ttattcgcca cattgtgccg aatgtactcg gtgtggtggt ggtctacgca tcacttctgg
    10861 tgcccagcat gatcctcttt gaatctttcc ttagcttcct ggggttgggt acgcaagagc
    10921 cgttaagcag ctggggtgca ttgctgagtg atggcgcgaa ctcgatggaa gtctctccat
    10981 ggttattgtt gttcccagcg ggattcctcg tggtgacgct gttttgtttc aactttatcg
    11041 gcgatggctt gcgtgatgcc ctcgacccga aagatcgtta aggagtgcag ccatgagcgt
    11101 aattgaaact gcaactgtgc cgctcgcaca acaacaggct gacgcactgc tgaacgtgaa
    11161 agatttgcgt gtcaccttta gtaccccgga cggcgacgtc acggcggtca atgatttgaa
    11221 tttttcccta cgtgccggag aaacgctggg tattgtaggt gagtctggtt cgggtaaatc
    11281 gcaaactgca tttgcgttga tgggcctgtt ggctgccaac ggacgtattg gcggatcggc
    11341 aaccttcaat gggcgtgaaa tcctcaattt gccagagcat gaactcaata aactgcgcgc
    11401 tgaacaaatc tcaatgattt ttcaggaccc aatgacttcg ttgaatccct atatgcgcgt
    11461 cggtgagcag ttgatggaag tgctgatgct gcataagaac atgagcaaag ctgaggcgtt
    11521 tgaagagtcg gtgcggatgc tcgatgcggt aaaaatgccg gaagcgcgta aacgcatgaa
    11581 aatgtacccg cacgaatttt ctggcggcat gcgtcagcga gtcatgattg cgatggcctt
    11641 gttatgtcga cctaagctgc tgattgcgga tgaaccaaca actgcgctgg acgtcaccgt
    11701 acaggcgcag atcatgacgc tattaaatga actgaagcgg gaatttaata ccgccatcat
    11761 tatgatcacc cacgatcttg gcgtggtggc ggggatctgc gacaaagtgc tggtaatgta
    11821 cgccgggcgc acgatggaat atggcaacgc gcgcgatgtc ttttatcaac ccgttcatcc
    11881 ttattctatc ggtttgctca acgcggtgcc gcgtctcgat gcggaaggtg aaacaatgtt
    11941 gaccatcccg ggtaatccgc caaacctgct gcgattaccg aaaggttgcc cgttccagcc
    12001 acgttgtccg catgcgatgg aaatttgtag tagcgcaccg ccgctggaag agtttacgcc
    12061 tggccgtctg cgtgcttgct ttaaaccggt ggaggaactg ttatgaatgc tgtaactgaa
    12121 ggaagaaaag tcctccttga aatcgccgat cttaaagtgc actttgaaat caaagatggc
    12181 aaacagtggt tctggcaacc gccgaaaacg ctcaaagccg tcgatggtgt cactcttcgc
    12241 ctgtatgaag gggaaacatt aggtgtggta ggggaatcgg gatgcggtaa gtccaccttt
    12301 gctcgcgcca tcatcggttt ggtcaaggcg accgacggtc atgttgcctg gttaggtaaa
    12361 gagttgctgg gcatgaaacc cgatgaatgg cgtgccgttc gcagtgatat tcagatgatt
    12421 ttccaggatc cgttggcatc gctaaacccg cgtatgacca tcggcgagat catcgctgaa
    12481 ccactacgta cttatcatcc gaaaatgtca cgccaggaag ttcgcgagcg cgtgaaggcg
    12541 atgatgctga aagtcgggtt attgcctaac ctgattaacc gctatccgca tgagttctct
    12601 ggtgggcagt gccagcgtat cgggattgcg cgtgctctta ttcttgaacc gaagctgatt
    12661 atctgtgatg agccggtgtc ggcgctggac gtgtcaattc aggcacaggt ggtcaacctg
    12721 ctccagcaat tgcaacgtga gatgggattg tcattaattt ttatcgctca tgacctggcc
    12781 gtggtaaaac acatttccga tcgtgtgttg gtgatgtatc tcggccatgc ggtagaactg
    12841 gggagctatg atgaggtcta ccacaatcca ctacatcctt acaccagggc attgatgtcg
    12901 gcagtcccca tacctgatcc ggatctggag aagaacaaaa ccatccagtt actggaaggg
    12961 gaattaccgt cgccgatcaa cccgccttcc ggttgtgttt tccgtacccg ttgcccgatt
    13021 gccggtccag agtgcgccaa aacacgtcct gttctggagg ggagtttcag acacgccgtt
    13081 tcttgcctga aagtcgatcc gctttaaaaa caataagggc tgacagttgt cagccctttt
    13141 tcacgctaaa agcgattatt tattcccgcc agatgatatg gcaaagtttg tgatcttttt
    13201 cgcggcataa cagaatgcgg gcaaaaacat cgttgatttc accatcttca ctgtccgcca
    13261 gaccaatcac cacttcggca aaaaagtccg ggttcaaatc gaaatcaaca tgttcctgcc
    13321 agtcttccgc cggatcgaat aactccgcgc cgccgcgctc ttcaaactga agattgaaca
    13381 gcagaacatc agctggatcg agattgtcgg cagccagttc gagaaaaata tcgtaggcct
    13441 gttcaagcgt ttcatcttca gtcaggcgat tgtttagatc catatccata gttactacct
    13501 gtttaacctc tgttggcgac gttttacagc aacggactga agaagtaaaa cagtcgctcg
    13561 gcgacacgtt gccataatgg acgttttagc cataaacggg catcgagcag acgtgaacgc
    13621 gaaatataat cgtcctgaac ggcggcgagg tcagcaccaa aacctttatc gtcgattgcc
    13681 agggtaatct cgaaatttag ccacagacta cgcatatcaa ggttaactgt gccaaccaga
    13741 cttagttcgc catcgaccag cacgctcttg gtatgcagta acccgccttc aaactgataa
    13801 attttaaccc cagcagccag cagttccgta aagaatgcgc gactggccca gccgaccagc
    13861 atcgagtcat tttttcgcgg aaggataata ctgacatcca ccccgcgctg cgccgccgtg
    13921 caaatcgcat gaagtaaatc atcgcttggc acaaagtagg gcgtggtcat gatcaaatat
    13981 tcacgcgccg aataagccgc agtcaataat gcctggtgaa tgagatcttc cggaaagccg
    14041 gggccagaag caattgtgtg aatggtgtga ccgctggcct gttcaaacgg cataatattg
    14101 acatctggtg gtggcggcag aatacgtttt ccggtttcaa tctcccagtc gcaggaataa
    14161 ataatcccca tcgcggtggc gatagggcct tccatacgcg ccatcagatc aatccattgc
    14221 cctacgcccg catcttgttt gaagtagcga ggatcgacca tattcatgct gccggtgtac
    14281 gcgatgtaat tatcgatcat gatcatcttg cgatgttggc gcaggtccat acggcgtaaa
    14341 aacacacgca tcagattgac ctttaaggct tcgaccactt caataccggc attacgcatt
    14401 agctcgggcc acgggctgcg gaaaaaagcc acactcccgg cggagtcgag catcaatcgg
    14461 caatgaatgc cgcgtcgcgc agccgccatt aatgattcag ccacctggtc cgccatgccg
    14521 ccgggctgcc agatataaaa caccatctca atattatggc gcgcgagctg gatgtcgcgg
    14581 attaacgcct gcatcacatc atctgactcg gtcatcagtt gtagctgatt ccctttgacc
    14641 ccagcgatcc cctgacgacg ctcgcaaagc ttgaataatg gcgcagcgac actgctattt
    14701 tcttcggcga agatatgctt acaggcttta aggtcgttaa gccattttgc ggtggaaggc
    14761 cacatcgctc tggcgcgctc agcgcggcgt ttgcctaaat ggagctcgcc aacggcaaga
    14821 taggcaataa ttccgactaa cggcagaatg taaataatca acagccaggc catcgcggag
    14881 ggaactgcgc gtcgtttcat tagaatgcgt aaagttacgc ctgcaatgag caaccagtat
    14941 cccagaatgg ccaaccaact caccaacgta taaacggttg tcatagatta gaaatccttt
    15001 tgaaagcgca ttgttatgag tttacgcata tggattcatc tggcaaataa aaacgcggga
    15061 aaagcactgg tcagcgtcgg gggtgggggt ataatgacca ttctgttatt gcatagagta
    15121 gttaacatga agcggagtag aacggaagtg gggcgctggc gcatgcagcg tcaggctagc
    15181 cgacgtaaat cgcgttggct tgaggggcaa tcgcgccgaa atatgcgtat ccacagcatc
    15241 aggaagtgca ttctaaacaa acagcgtaac tcgttattgt ttgcgatcta caatatctaa
    15301 atgtactggg caccattgcg gtgcccaata agtttactct tccgtcttta aactctattt
    15361 ttgcgccgat tctttactgt cagctttcgt ttctagttca tcgttatcgc tgaaaatacc
    15421 atgacctgag ttcaacaaca ttgaaacgag catatcatta ttaatctctt caccatttaa
    15481 aactcgcgcc agaatttcgc tgccaaacag ttgcggtgag agaatgatat ccggatgtac
    15541 catcttaatc ttattcaggt ttttgctatc actgacggcg agaactgttt tgacatcact
    15601 gctcatatct tttgccgaga gtacaacaaa cgcgttatct gcatcgttat cactcagcgc
    15661 cagaatggcc cggcaacgat cgattcccgc tttctttaat acagaactgt cattactgtc
    15721 accggggata acatcagcat tatcgcctaa gcgttgctca agttgcttga tatcatcttc
    15781 aggcaagttg ctgataaccg ttacgttttg tccgcgttga ttcagttgca ggatcgtatt
    15841 gatggcgaga atcgaatgtc cgcaaacaat aaaatgatct ttacgatgca ttgtatgatt
    15901 gtttcctttt acaagtttgt tgaatccccc gcggataagc ggaccaaaaa ttgaggtcat
    15961 agatgtggca aaaacggtaa tgccggaaat aatgaccgaa atagtgaaca atcgtgctga
    16021 ttcagaaaca gggacaatat cgccatagcc gacggttgac atggtttcta tcgaaaaata
    16081 gaacgcggtc atcaaacttt ctattcgcgg attaaaacct tcgcttaaat aaagcgcacc
    16141 gtaggttgag taaaacagta atgtcgtgaa actaataaat gcaaaaattg tcccggctgc
    16201 ggcgctactg tgggagaagt ctttgcgcag tatcagcaaa aacaccagcg taaaaatgca
    16261 aaatccaata ctaaatttca gccagggata aaaatgcagg gtgtaaatta gcgctatcaa
    16321 caacaaaatg atactgattg cccatgcgag ctttgcccgg aacagtaagc caatggagtt
    16381 caggacaaga aagacgccga gcataaagag tggggcgttt gccagcaagg agagatccaa
    16441 ctctgaaaat gctttgatat ggaaaatatc aagcaaattg accgacatac catagattgt
    16501 tttaaaaata agcaatccat ttaaaaagac ggccagcgcg agaatgtcgt gccgaagggt
    16561 cacccataaa tttgttgctg tttgtttgaa tgtagcccag tgactcactg atacctctgt
    16621 aaccacaatt ttgtttaatt atcttagcgt gcacattttc tgaacataca tgcagcgcgt
    16681 gaatgtgtta aacaatagta gatgacttta tccgcagtaa tcaaaggatt tgagcgagca
    16741 actgtacctc aggaaaggtc atttttcctg aatatgctca catcatataa agaaatacag
    16801 ataaagttat tatctgcttg tggtggtgaa tgcactgacc ggctataagg aaaggccaaa
    16861 caagaacacg gttgcaaaaa ccgtgccctt aaatattgaa tctctattca gaacactttc
    16921 ttaaatggtt tcactgaaac gtgttcatag actcctgccg ctacgtacgg gtcagcatcg
    16981 gcccaggcct gagctgcttc cagcgattca aattcagcaa taacggttga gccagtaaat
    17041 cccgcagccc ctggatcgtt actgtctacc gctggcattg gaccagctgt caacaaacga
    17101 ccttcatcat gcagtaactg taaacgtgct aaatgtgccg gacgaacgga aaggcgtttt
    17161 tcgaggctat cagctttgtc ttgagcgtaa ataacataca acacgggcac aactccttgt
    17221 tcgggaaagt tgtaaagtac gttatttgaa agggcgaaga tctgcaacgg aaagatgatg
    17281 tctttgttaa ggccatgcat aaagtaaggg taattacgcc aaaaatgaca ttttcactga
    17341 tcctgatcgt cttgccttat tgaatatgat tgctatttgc atttaaaatc gagacctggt
    17401 ttttctactg aaatgattat gacttcaatg acccttgatt tacctcgccg cttcccctgg
    17461 ccgacgttac tttcggtctg cattcatggt gctgttgtgg cgggtctgct ctatacctcg
    17521 gtacatcagg ttattgaact acctgcacct gcgcagccga tttctgtcac gatggttacg
    17581 cctgctgatc tcgaaccgcc acaagccgtt cagccgccac cggagccggt ggtagagcca
    17641 gaaccggaac ctgagccgat ccccgaaccg ccaaaagaag caccggtggt cattgaaaag
    17701 ccgaagccga aacctaagcc aaaaccgaag ccggtgaaaa aggtacagga gcagccaaaa
    17761 cgcgatgtca aacccgtaga gtcgcgtccg gcatcaccgt ttgaaaatac ggcaccggca
    17821 cgcctgacat caagtacagc aacggctgca accagcaagc cggttaccag tgtggcttca
    17881 ggaccacgcg cattaagccg taatcagccg cagtatccgg cacgagcaca ggcattgcgc
    17941 attgaagggc aggttaaagt taaatttgac gttacgccgg atggtcgcgt ggataacgta
    18001 caaatcctct cagccaagcc tgcgaacatg tttgagcgtg aggtgaaaaa tgcgatgcgc
    18061 agatggcgtt atgagccggg taagccaggc agtgggattg tggtgaatat cctgtttaaa
    18121 attaacggca ccaccgaaat tcagtaagca gaaagtcaaa agcctccgac cggaggcttt
    18181 tgactattac tcaacaggta aggcgcgagg ttttccttca ggatcaaccg cgacatactt
    18241 aaataatgct tctgtcgctt tatagcgttg cccaattggt tcagacgcta cttttttcac
    18301 ccacacttca atattaatgc tgaccgatgt cgtccctttc tggacacagc gtgcatagca
    18361 gcacaccaca tcgccgaccg caaccggccg taagaaagtc attccttcaa cccgcacagt
    18421 cactacgcga ccgtgggcaa tttcttttgc cagaatagcg ccgccaatat ccatttgtga
    18481 cattaaccaa ccaccaaaga tgtcaccatt ggcattggta tcggcgggca tggctaaagt
    18541 acgtaaaaca agatcgccct gagggacgtt atgtgttgta gacatggtaa aaccgactta
    18601 aaaggaaaat cacaggcgcg atgctactat gattttcctg aggagaacag aggagataca
    18661 gcgccagccc cgaaggactg gcagtctggt taggatttat cttcctgcgg catgtggcgg
    18721 tagatataga taccgcttaa caatgtgaag attaaggtaa gggcggtcag gccaaagact
    18781 ttaaagttga cccaaatatt ttgcggcagc cagaatgcga tgtagatgtt tgccagaccg
    18841 caaaggataa agaaaacagc ccaggccagg ttcagcttcg accataccgg ttgcggcagc
    18901 gtgagttctt tacccagcat ccgctgaatt agcggctttt tcatcaccca ttggctgact
    18961 aacagggctc ccgcaaatag agcataaatg actgtaacct tccatttaat aaactcatca
    19021 ttgtggaaga acagcgtcaa gccaccgaag acgaccacca gaacaaaagt gatcagggcc
    19081 atcttctcaa ccttacgaaa gcgaacccag ctatagataa gcacaatcgc cgtggcgacg
    19141 atcagcgccg cagtagccgc atagatgtca taaatcttgt aaaacgcgaa aaagacaacc
    19201 agcggtaaaa aatcaagaaa ctgcttcatt ttacgattcc gtaatcaaat gcttaaggtt
    19261 attggcgaat caacatatac aggcggaaca gatagatgag caatatggct gaaatcaggt
    19321 tgctcaaggt gttcgccagt acggcaccaa tttccggggt taatgcggca aaagaagagg
    19381 caaaaagcag caacagtgtt tttgccagca accagctcag tactgcgggt gccaccagac
    19441 gcatattcgc ccaagtcagc cgcatactgc tacgcatcga ggcaaaaacg cccattttgt
    19501 cctgtaccaa catcaccggt gccagggcca gtaaaatggc catgataatt cccggaacga
    19561 ccaccagcat gatgccaatc tgtactaaaa gggtagtcag aaaaatcaga ataaataact
    19621 ttggcaatat cggcgcactg gcaccaatag ctcgcagcgc actgactctc tgacccgcag
    19681 acaccagctg gataattaat attacgcctc cggcgagaat ggcgttaccg attaatcctg
    19741 aaaaagtgga cgccgctgaa gcctgcagca aaatttgttg ctgttccggt gacatattct
    19801 gaaccaggtc gaacaaccca ctactgccgc taacgggcac gccgtcattg agctgcgcaa
    19861 gctgtgcatc actgggtgag aaaacatgcc ctaacaccac tgtgataaac gcacatagca
    19921 acgataccaa cagaatggtc ataaattgat tacggaagaa atttccggtg tcacggtata
    19981 cggactgcgc cgtgatagac atgcactctc cttgagtttt atgcaggtgt taattagcgg
    20041 gcaattgtac cctggttaag cctcgggtgg cagcatcagg tcttgtatgg aaaagcatat
    20101 ctttgtaaag cggaggtaat tgctggcctt caggcatggg caaatcgcgg caagtggcga
    20161 ccgagttaat atttgcgtag cgaaaatatt taaaaattga tttaaatcac attaaccagg
    20221 attctcaatg caacttctaa attaatccag atcaataaag ggtgaattat catatgtaat
    20281 gtgatctatg taggatcatt tgttactcca atgtaggtat attcgtcacg tttttataac
    20341 cataacgacg gagcggatat gaaaaagtta acagtggcgg ctttggcagt aacaactctt
    20401 ctctctggca gtgcctttgc gcatgaagca ggcgaatttt ttatgcgtgc aggttctgca
    20461 accgtacgtc caacagaagg tgctggtggt acgttaggaa gtctgggtgg attcagcgtg
    20521 accaataaca cgcaactggg ccttacgttt acttatatgg cgaccgacaa cattggtgtg
    20581 gaattactgg cagcgacgcc gttccgccat aaaatcggca cccgggcgac cggcgatatt
    20641 gcaaccgttc atcatctgcc accaacactg atggcgcagt ggtattttgg tgatgccagc
    20701 agcaaattcc gtccttacgt tggggcaggt attaactaca ccaccttctt tgataatgga
    20761 tttaacgatc atggcaaaga ggcagggctt tccgatctca gtctgaaaga ttcctgggga
    20821 gctgccgggc aggtgggggt tgattatctg attaaccgtg actggttggt taacatgtca
    20881 gtgtggtaca tggatatcga taccaccgcc aattataagc tgggcggtgc acagcaacac
    20941 gatagcgtac gcctcgatcc gtgggtgttt atgttctcag caggatatcg tttttaattc
    21001 cgcacaaaaa cgaccccgta atatacgggg tcaataagga catggtataa agggtattat
    21061 ttcttcgctt ctacgccatc agtttcagag cgaattaaaa atttctcagt tgtttgcgga
    21121 atattctgaa tcagccagtc ggccatttgc ttttcctcat ttaaaatcgc ttcgatggtt
    21181 ggaattgaag ctgtatcacc ggcatttttt gctgctgcta atagtgaggt gtaacaggcg
    21241 atttcaaatt gctcgaagac atatccgcta atagagcctt tgactatttc atcagaaggg
    21301 aatataccac cgattgactg cccaagcgca gccattttac tcatggaatc tttaatgact
    21361 gaacgtgaaa tgtcattacg atcaagaata gtttccagtt gaacaatctg gtttttggtt
    21421 tcactaagat gttgttcaat acgagcgcgt agttcaggat aattatctat acggctggcc
    21481 atggattcaa gcatagattc ggcttgcttt tccattgcgt gggcgtcacg taaccagtca
    21541 tgataatgtt caatacgatt catgaaaatg tcctctttat aaaatgacta aaagttaaaa
    21601 ttcatatttc aggctttatt ttcggctttc ttatttacgt tattaatggc cagatcagtc
    21661 agtttgatgt cggtggcctt ttcttcttcc agggtttctt tcagaagctt cgctgcttta
    21721 cggtaaccta attgttcagc cagcgtcgct aatgtcccgt aactggcaat ctcataatgc
    21781 tcgactttct gtgctgcggc aatcagtgcg gcatcacgca cttcgttttt ctcggtactt
    21841 tcgatgacct cattagcttc ttcaataaga ccttccattg ccacacattt catgcgctta
    21901 attttcaggt tcgattcgga ctccacaact tgatcaatac gttcaatctg tccatgagtt
    21961 tcctcgaggt gcgcatgaaa agcctgactt aatttttcat ttgatgttgc tcttgcgagt
    22021 tttgccagtg cccgggttaa ttgtttttct gcgctgtagg tatctgaaag caggtgaata
    22081 aatacatctt caatggtctt catattcata tttttctcca gtgaaatcac tgcgagccat
    22141 acggcccgca gatgcaatta tctttatcag ctgatattaa taattaacgg tgaatcagga
    22201 tttgcctgat ttattaccac cgctttgttg accgcctttt ttacccgctt cagatgcgcg
    22261 ttgcggatca tttttaaaat taccgccgct atgctgaccg cctttacggc ctgcgtcgga
    22321 tgccttctca cggtcttcgg cgaaatttcc tgaaccacca cgatgttcgg ccatgttatt
    22381 tctcccgttg cgttgcattg tttcattaat atgagtgttg tgtgtcgaca ctcattaaaa
    22441 ttagtcgcta atgagaatta gtcaaattaa gcgcaacgag aagatagagg gaaaatatat
    22501 tttgaggaac attctggata tattaacaat tacctgagga ataagtgact tagagaaaat
    22561 tattgatttt actggtgtta tgttgcggga ttaatttgtt tgattatatt actgttgggc
    22621 ggaaaaatga cgtaagttga cgttcgaccg gggtaagcga aacggtaaaa agataaatat
    22681 taaatgaatt taggattttt ccggcttcat taaagaaagt taaaatgccg ccagcggaac
    22741 tggcggctgt gggattaact gcgcgtcgcc gctttcatcg gttgtacaaa aactttcagt
    22801 gccgccagca ttttctctgg ctcattaata tgttgctcga tgattttaac aatggccgaa
    22861 ccagaaatcg cgcccgcagc tcctgcatca atcgctgctt ttacctgatc cggggcggaa
    22921 ataccaaatc cctgcaatgg aggtgcagcg ttgtactctt tcagcttcgc aaccagatga
    22981 ttgaggggta acgcggcgcg gttttctgcg ccggtcacgc ctgctcgtga cagcaaatag
    23041 gtgtaaccac gaccgtaaga ggctatctgg cgcagcaggt cgtcatcggc atttggcggg
    23101 cagatgaaga taggtgcgac attatgacgc aacgcggcct ggcggaaggg cgcggactct
    23161 tcaactggca catcggcaac cagcaccgaa tcgacgccga ctttttcgca ctgggcataa
    23221 aactcatcaa tgcctttgtt aaacaccaga ttggcataca tcaacaggcc aatgggaatg
    23281 gtcgggtgtt tctggcgaat cagtgccagc atttcaaaac attgtgccgg agtcacacct
    23341 gccgcaaagg cgcgcagagt ggcgttttga atcgtcgggc catccgccag tgggtcggag
    23401 aaggggatac ctaactccag cgcgtcagca ccggcttcaa ttagcgtatc gataattttc
    23461 aatgactgct caatgcccgg atcaccgagc gtgacgaaag gaacgaatgc gccttctttg
    23521 cgctccttca actgggcaaa cagagattcg tagcgttcca tcagatttcc cctcgtgctt
    23581 tcaaaatatc gtgaacggtg aagatgtctt tatcgccgcg accggaaagg ttaaccacca
    23641 gtagctgctc tttatccggg ttttcgcgca tcattttcaa cgcatgggcc agggcgtggg
    23701 aggattccag cgccgggatg atcccttcgt gcaggcacag cgttttgaag gcttcaaggg
    23761 cttcatcatc ggtaatagac acgtaatcag cgcgtccagt gctgttaaga tacgcgtgtt
    23821 gtgggccgac agacgggaaa tccagtccgg cggagatgga gtaagattct tcaatctgcc
    23881 cgtcttcggt ttgcatcatc ggcgctttca taccgaaata gatacccacg cgaccatgtt
    23941 ttagcggtgc gccgtgctcg ccagtttcga taccgtgacc acctggctcc acaccaatca
    24001 ggccgacgtt ggtttcattg atgaaatcag caaacatgcc gatggcattc gaaccgccgc
    24061 caacacaggc gataacggca tccggcaggc gaccttctct ttccagaatc tgcgctttgg
    24121 tttcttcgcc aatcatccgc tgaaactcac gcacaatggt cggataagga tgcgggccag
    24181 ctgcggtgcc cagcatatag tgcgcggttt cgtaactacc ggaccagtcg cgcagcgcct
    24241 cgttacaggc atctttcagc gtcgcggaac cgctatgcac agggatcact tccgcaccca
    24301 ttaagcgcat acgaaaaacg ttaggcgact ggcgttcaac gtctttggca cccatataaa
    24361 tacggcattt caggccgagc agggcgctgg caagggccga cgccacgcca tgctgaccgg
    24421 caccggtttc ggcgatgatt tcggttttat ccatccgctt cgccagcaac gcctgcccca
    24481 gcacctggtt agttttatgc gcgccgccgt gcagcaaatc ttcacgcttg agatacagcg
    24541 tggtgttcgt cccggctgta atgttctggc atttggtcag cgcggttgga cgcccggcat
    24601 agtttttcag caggtcgttg aactgagcct gaaattcagg atctttttgc gcactgacaa
    24661 aagcttcttc cagctggcgc agagcaggca tcaggatttg tggcacgtac atgccgccaa
    24721 actcaccaaa ataggggtta agtaatgttg tcattgttcc tttccttaat atgcgcgcag
    24781 cgtctggaaa accgaggcca aaagacgtgc gtctttgatg cccggttgcg actctacagc
    24841 agaattaaaa tcaagtccgg cgcagccggt ttgtgccgct tccacgcagt tatctgcgcc
    24901 taagcccccc gccagcagaa cgttgccaag cgattgacca tttaatagtg accagtcaaa
    24961 acgttgcccg cttccaccct ggccgttgtc taaaacatat ttatcaacgt gctgaaactc
    25021 gcgggcgggc agggtttcac cgacgcttaa tgctttccag atggcaacat gtgctggcag
    25081 agcttcacgc agcgtatcga tatacagctg ttcttcatta ccatgcagtt gcactgccgc
    25141 cagcgataac accttagctt tgtccaccac atcggcaata tcgtgattgc ggaacacgcc
    25201 aacatactgc aacggtgccg cagccatcac ttcctgcgcc tgttcaacgt tgacgcaacg
    25261 cggtgatgtc gcaacaaaaa tcaacccacc gtaaatcgcg cccgcgtcat aagctgcttt
    25321 agcatcttgc ccacgcgtca ggccacatac tttattctca cccagcaaca cccggcgcac
    25381 ggcggcgtgc aaatcgtcat gggccatcaa cgccgaacca atcagaaaac cgttagcgaa
    25441 gtggcttaac tcgcgcacct gagcgtaagt attgatgccg gattcgctga ttaccgtcac
    25501 gttgtgcccc agtttcggcg caagctcgcg ggtacggttg agatcaatcg acaaatcacg
    25561 cagatcgcgg ttgttgatgc caacgacctt tgctcccaat gcaatggcgc gctcctgttc
    25621 ctcttcatta ctgacttcgg tcagcacccc catctccaga ctgtgagcga cggcggcaag
    25681 ctggcgatat tggtcgtcat ccagtactga aagcattaat aagcaggcat cggcctggta
    25741 atagcgcgcc agatagatct ggtaagggtc gataatgaag tctttacata aaatcggctg
    25801 cggggcgatt tggctgacga tggggaggaa attaaagctc ccctgaaaat atttctcatc
    25861 agtcagcacc gaaattgccg aagcgtaatg tttataaatg gcggcaatgc gtgctggatc
    25921 gaaatcatca cggatcacgc cttttgacgg cgacgctttc ttgcactcca gaataaacgc
    25981 cgtgcgcgca ccctgtagcg catcataaaa atgtcgcgtg ctcggctgaa cctcattctg
    26041 aaaactggcc agcggttgct gctgtttgcg ggcttctacc caaatcgcct tgtctgcgac
    26101 gattttcgct aaaacggttt gcatcattta ccctcgtgcc gccagtgcgg tgactctgtc
    26161 gtaagcggaa ccactgcgca gtacctcaag aacggtttgc gcattggctt gcagatcttc
    26221 atggccatgc aggcgcatta acatggcgac gttcgcagcg acggctgctt catgggcggc
    26281 gtcgccttta ccttgtaaca aacgtgttaa aatgtcacgg ttttcttccg gtgttccgcc
    26341 tgccagttgc tcctggtggt agggtgtcag gccaaagtct tctgcggtga gctgatagct
    26401 tttaatttcg ccgtcatgca gttcggcaac gattgtcggc gcgtgtaatg aaacttcatc
    26461 catcccgccg ctgtgcacca ccgccgcgcg ttgatacccc agcacgcgca aggtttcggc
    26521 aatcggcagc accagttccg gactataaac accaattaac gccagcggcg gatgcgccgg
    26581 gttaatcaat ggccccagca cattgaacag ggtgcgggtt ttcagttgct ggcgaaccgg
    26641 catcgcgtgg cggaatccgg tgtgatactt cggcgcaaag aggaaacata cacctaactc
    26701 atccagcgcc tggcgcgatt tatcggcgtt catatcaaga ttaataccga acgccgccag
    26761 cagatcggac gaaccagatt tactggagac gctacggttg ccgtgtttcg ccactttcag
    26821 cccacaggcc gcggcgacaa acgcactggc ggtagaaata ttgatactgt tgctgccgtc
    26881 accgccagta ccgacgatat cagcaaacag ataatccggg cgcgggaacg gcgctgcgtt
    26941 ttccagtagc gcggttgctg ccccggcgat ctcgttcggg tgctcaccgc gaattttcat
    27001 gctcaccagc gccgccgcca gttgttccgg cttcagctcg ccacgcacca ccgctgaaaa
    27061 cagctggtgg ctttcttgtt ggctaagcgt ctgcgcctga tacagttttt ccagaatcgg
    27121 ttgcagcgtg ttggctggct ctagtttctg ctgcgcccag gccagcgttt gttccagcag
    27181 gcgagcgccc tgggtggtga gaatggattc cggatggaac tggaatccac aaacgcgatc
    27241 cgcatcgtga cgtactgcca tcaccatgcc attaaaatgg gcgttgatgg ttaaaccggc
    27301 cggaatgtta ctgccaacca gcgagtgata acgcgccacc ggcagcgggt ttgttaatcc
    27361 ggcaaacatc gcctgaccgt catgttcaat gctggaggct ttaccgtgga gaatttcgcc
    27421 cgcctgaccg acatagcccc cgtaagcttc gacaatcgcc tgatgtccga ggcaaatgcc
    27481 aataatgggc agcttgccac gcaagcgggt gaggagttcc ggcatacaac cggcttcgct
    27541 cggcacaccg gggccaggag aaagcatcag caccggattg ctcatggtcg ccaggcgttc
    27601 aattaaggtt tgcgccggaa tatggttgcg gtaaatcacc acgttatgcc cattgctgcg
    27661 caactgatct gccaggttgt acgtaaaaga gtcgatatta tcgagcagca gaatgtcagc
    27721 catcagaaag tctcctgtgc atgatgcgcg gtggcaatag cgcgcagtac agcgcgggct
    27781 ttgttacggg tttcgtcggc ttccgactgc ggaacagaat caaggactac accagcaccc
    27841 gcttgcacgg tggcgatacc gttttccacc agcgccgagc ggatcacaat gcaggtgtcg
    27901 agatcgccat gcgcggtgaa ataacctacc gcgccgccgt agctgccgcg gcgacgacct
    27961 tccgcctcgg caattaactg catagcgcgt actttcggcg caccgcttaa cgtccccata
    28021 ttcatacagg cgcgataagc gtgcagggcg tcaagatcgt gacgcagttc gccgactacg
    28081 cgagagacga ggtgcatcac ataggaataa cggtcaactt tggtgagatc ggcgacgtag
    28141 cggctgccgg gggtgcaaat gcgtgccaga tcattacggg cgagatcaac cagcatcaga
    28201 tgttcagaca gctctttatg atcggtacgc atttccagtt caatacggct gtcgagatct
    28261 ctgtccagtg aaccatcggc gcgacgaccg cgtgggcgtg ttccggcaat cgggtagatc
    28321 tcaatctggc ggctggtggc atcatacttg agcgagcttt ccggcgacgc gccaaatagg
    28381 gtgaaatcat tatcctgcat aaaaaacatg tacgggctgg gattactctt tttcagcacg
    28441 taataggccg ccagcggtga cgggcagggc agagagaaac ggcgagatgg caccacctgg
    28501 aaaatttctc cagcgcgaat cgctttttgc aacaaacgca ctacgccacc gaactcttca
    28561 tcgctctgat tacattcaca acgcatatgc ggcacggaaa ccactggcag cggcggcgcg
    28621 gcttcggtca gttgctgacg tagttcgttc aggcgagcag tgagacgttg tttttcttct
    28681 tcattcggag caaacaggct ggcctgaata cgggtgcttt ttttctgatg gtcaatcacc
    28741 atcagcgttt cagcgagata aaaacagaaa tcagggcagt tattttccgc tgacagttgc
    28801 ggtaaatctt caaatcccgc cacaaggtca taagagaaca ggccgccgaa gaacatggct
    28861 tctcgttctt ccttcggtac attcaacaga ttctgcaata aacggaaagc gtcaaaaacc
    28921 gaaagggagc ataagcgggc gtcttcatcc agcagtggac tgacaggggg gaagcgcagc
    28981 acacggcagt ttggtgattg ttcactttcc acacccgcag gcagggcgtt atccagtagt
    29041 gccagcaggg cttcgccgtt gccggaaagt gcctggattg tgacagtgtc acctaaagct
    29101 gtaatgcgca gcgcactgtc taccagcagc aggcttttta aatcatcttt gctgtcgata
    29161 tctgcggatt ccagcagcag cgttgccgga cgatccccac acaactggtg aaaaagcgcg
    29221 gtgggattgt cgcgataagc gccttcgcag gttagcagtt cgagagtcgg tttttgtgtt
    29281 tgcattgtta ttctctaatt ttgttcaaaa aaaagcccgc tcattaggcg ggctgggtat
    29341 ctgattgctt tacgcatggt gaatacactg cccgtttcag gaagtgcgcc accaaccttt
    29401 cagtacgaaa attgctttca ttgtcgatac cctttttacg tgaacttgcg tactagttaa
    29461 ctagttcgat gattaattgt caacagctca tttcagaata tttgccagaa ccgttatgat
    29521 gtcggcgcaa aaaacattat ccagaacggg agtgcgcctt gagcgacacg aattatgcag
    29581 tgatttacga cctgcacagc cataccacag cttccgatgg ctgcctgacg ccagaagcat
    29641 tggtgcaccg tgcagtcgag atgcgcgtcg gcaccctggc gatcaccgac catgacacca
    29701 cagctgcaat cgcgccagca agagaggaaa tttcacgttc gggactggcg ttgaatctta
    29761 ttcccggcgt ggaaatttcc acggtctggg aaaatcatga aattcatatt gtcgggctga
    29821 atattgatat tactcatccg ctaatgtgtg agttcctcgc gcagcagaca gaacggcgca
    29881 atcagcgggc gcagctgatt gccgaaagac ttgaaaaagc gcaaatacct ggggcgctgg
    29941 aaggcgcaca acgactggcg cagggcggcg cagtgacgcg cggtcatttt gcgcgtttcc
    30001 ttgttgagtg cggcaaagcc agttcaatgg cggatgtctt taaaaagtat ctggcgcgcg
    30061 ggaaaaccgg atacgttccg ccacagtggt gtacaataga acaagctatt gatgtcattc
    30121 atcattctgg cggtaaggcg gtgctagctc atcctgggcg gtacaatctt agtgctaaat
    30181 ggctgaaaag attggttgcg cattttgccg aacaccacgg tgacgcgatg gaagtcgcgc
    30241 agtgccagca atcgcccaat gaacgtaccc agctggcggc ccttgcgcgt cagcatcatt
    30301 tatgggcatc acaaggatct gattttcatc agccatgccc gtggatcgaa ctgggtcgta
    30361 aactctggct gcccgcaggc gttgaaggcg tctggcagct atgggaacag ccgcagaaca
    30421 ccacagagag ggaattatga gccagttttt ttatattcat cctgataacc cacagcaacg
    30481 tctgatcaac caggcggtgg agatcgtgcg taaaggcggg gtgattgttt atccaactga
    30541 ttccggctat gcgctcggct gtaaaattga agataaaaac gcgatggagc gtatttgtcg
    30601 tattcgccag ctgccggacg gtcacaactt taccctgatg tgtcgcgatc tttctgaact
    30661 ctcgacctat tcatttgttg ataacgttgc gtttcgttta atgaaaaaca acacgccggg
    30721 caactatacc ttcatcctga aggggacgaa ggaagtgcca cgccgtctgt tgcaggaaaa
    30781 acgcaaaacc atcggtatgc gtgtgccttc taaccctatc gctcaggcgt tacttgaagc
    30841 attgggcgaa ccgatgcttt ccacttcgct aatgctgcca ggcagcgaat ttaccgaatc
    30901 ggacccggaa gaaattaaag atcgtctgga aaaacaggta gatttgatta ttcacggcgg
    30961 ctatctcggg cagaaaccga caacggttat tgatcttacc gatgatacgc cggtcgtggt
    31021 gcgtgaaggc gtaggtgatg tgaagccttt cttataacaa attgcgttcc acggatggaa
    31081 gactatggca gggaagtttc gctgcatttt gctgttgata gcagggctgt ttgtatcatc
    31141 tctaagttat gcagaaaaca cggagatccc ttcttatgaa gaagggatct cgctctttga
    31201 tgttgaagcc actctgcaac cagatggggt gctcgacatc aaagaaaata ttcattttca
    31261 ggcgcgaaat cagcagatta agcacggctt ttatcgtgat ttaccacgac tatggatgca
    31321 gcctgatggg gacgctgcac tgctgaacta tcatattgtt ggcgtcaccc gtgatggtat
    31381 tcctgaaccc tggcatcttg actggcatat cgggttaatg agtattgtcg tgggcgataa
    31441 acaacgtttc ttgcctcaag gcgactatca ttatcaaatt cattatcagg ttaaaaatgc
    31501 tttcctgcgt gagggggatt ctgatctgct aatctggaac gtgaccggta accactggcc
    31561 gtttgaaatt tataagaccc gtttttctct ccagttctct aatattgcgg gtaatccatt
    31621 tagcgaaatc gatctcttta ccggagaaga gggcgacaca tatcgtaatg gccgcatcct
    31681 tgaggacgga agaattgaat cccgcgatcc gttttatcgt gaagatttca cggtcctcta
    31741 ccgctggcct cacgctttac ttagcaatgc ctcggctccg caaacgacga atattttcag
    31801 ccatcttctt ttaccctcca cgtcatcgtt gttaatttgg tttccgtgtc tgttcctggt
    31861 ttgtggatgg ttatatctct ggaagcgcag gccgcaattt acgccggtag atgtgattga
    31921 aaccgatgtc attccgccag attacacgcc cggcatgtta cgtctcgatg cgaagctagt
    31981 ttacgacgat aaaggttttt gtgccgatat cgtaaatctg attgtgaaag gaaaaattca
    32041 tctggaagat cagtctgaca agaaccagca aatcctgatt cgtgttaatg aaggcgcgac
    32101 cagaaataat gcggtattac tgcccgcaga gcagttatta ctggaagcgt tatttcgtaa
    32161 aggcgataag gtcgttctta cggggagacg caacagagtc ttacgcaggg catttttacg
    32221 gatgcagaaa ttttatctgc cgcgtaaaaa gtcttcgttt taccggtctg atactttttt
    32281 gcaatggggt ggactggcaa tattggcggt cattctttac ggtaacttga gtcctgtagg
    32341 ctgggcagga atgagtctgg tgggcgatat gtttattatg atctgctgga ttattccttt
    32401 tttattttgt tcccttgagc ttttgtttgc ccgcgatgat gacaagcctt gcgttaatcg
    32461 tgtaatcatc actttgtttt taccactgat ttgttcaggc gtggccttct attctctcta
    32521 catcaatgtc ggagatgtat tcttttactg gtatatgcca gcgggttatt ttaccgctgt
    32581 ttgcctgacc ggttatctca ctggcatggg gtatattttt ctgccaaagt ttacccaaac
    32641 tggacagcaa cgttatgccc acggtgaagc tatcgttaac tatcttgcgc gtaaagaggc
    32701 agcaacacac agtggacgtc ggcggaaagg ggaaacacgg aaactggatt acgcgttgct
    32761 aggttgggct atatcggcaa atttggggag ggaatgggcg ttacgcattg ccccttcgct
    32821 ttcttcggcg attcgcgctc cagagattgc ccgtaacggc gttttattct cattacagac
    32881 gcacctaagt tgcggggcca ataccagttt gttggggcga agttattccg gtggtggtgc
    32941 tggcggcggc gcgggtggcg gaggcggtgg tggctggtaa ttaagctgat gttaatcgaa
    33001 acaagcttta accataaaga tagtgtagta tgttgcgcct caaagccagg ccgataaacg
    33061 tcgagtcgtt tacttaaggc ctgaagagtt caaacagact ttactatcag tgagtcagat
    33121 gtaagttctg actcactgtt gcacaaaagc atatcagacg cctgggaagg cgacaccaaa
    33181 aggaagctct atgagcgaaa agctacagaa agtgctggcg cgtgccggcc acggttctcg
    33241 ccgtgaaatc gaatctatta ttgaagccgg tcgtgtgagt gttgatggca aaattgctaa
    33301 actcggcgat cgtgttgaag ttacccctgg attgaaaatc cgtatcgatg gtcacctgat
    33361 ttcggtacgt gagtccgctg aacaaatttg tcgcgttctg gcctattaca aaccggaagg
    33421 tgagttgtgt acccgtaacg atccggaagg acgtccaacg gtgtttgacc gtctgccaaa
    33481 actgcgtggc gcacgctgga ttgccgtggg tcgcttggac gttaatacct gtggtctgct
    33541 gctgttcacc accgatggtg aactggcaaa ccgtttaatg cacccaagcc gtgaagttga
    33601 acgtgaatat gccgtgcgtg tatttggtca ggttgacgac gcgaaactgc gtgatttgag
    33661 tcgtggcgtg cagttggaag atggtccggc agcttttaaa accatcaagt tcagcggcgg
    33721 cgaagggatc aaccagtggt acaacgtgac tctgaccgaa ggccgtaacc gtgaagttcg
    33781 tcgtctgtgg gaagcggttg gtgtgcaggt gagccgcctg atccgtgttc gttacggtga
    33841 tatcccactg ccaaaaggtc tgccacgcgg tggctggacg gagctggacc tcgcccagac
    33901 taactatctg cgcgaactgg tggagctacc gccagaaacc agctctaaag tcgctgttga
    33961 aaaagaccgt cgtcgcatga aggcgaatca gattcgtcgt gcggtgaaac gtcacagtca
    34021 ggtgagcggc ggtcgtcgtt ctggcggacg taataataac ggttaatcaa agtatgccgg
    34081 acgtcatatc cggcattttt acagattaat aatcgatccc tatctgcgct tttacaccgg
    34141 catcaaacgc atgtttgacg gggcgtaatt cacttaccgt atctgccagt tcaagaatat
    34201 cccgatgaca accacgaccc gtgataatca ccgtctgttg atgtggacgt tcatttaacg
    34261 cctgcaccac ttcttccagt ggcaaatagt catacgccac catatacgtc agttcatcaa
    34321 gcaaaaccat atccagtgag gaatcagcaa gcatccgctt tgcatgttgc cagacttcgc
    34381 ggcaggcggc ggtatcagac tcgcggtttt gtgtatccca ggtaaagccc gttgccatca
    34441 cctgaaactc aacgccatgt ggctccagca gattgcgttc gccattaggc caggtgcctt
    34501 taataaactg cacgacgcct actttttttc cgtgaccaac tgcgcgtgtt gccgtaccaa
    34561 atgccgcggt ggttttgcct tttccattgc cggtaaagac gatgataata ccgcgttcat
    34621 cctgggcctg ggccacacga gcatctactt tttctttcac tcgctgctga cgctgttggt
    34681 agcgttcatc actcattggg aaattcctgg tttacggccc ggttgggcgt caaaggtcat
    34741 gccggtttta cggcggctgt catcgcccat cagccagagg tagagcggca tgatatcagc
    34801 gggtgtttta agtttctgtg gatcttcggt cgggaaggcg ctggcacgca ttgcggtgcg
    34861 cgtaccgcct gggttaatgc agttgacacg caggcgctgc tgatattcat cggccagtac
    34921 ctgcatcatc ccttcggtgg caaatttcga cgctgcatat gcaccccagt tggctcgtcc
    34981 ctgacgtcca acgcttgatg aagtaaagac cagtgaaccg gcgtccgatt tgagtaataa
    35041 aggaagcagt gcctgggtga gcataaaggt ggcattaacg ttgacctgca tgacgtcctg
    35101 ccagacctgc ggattttgtt cgctcattgg gcaaacatcg ccgagcaatc cggcattatg
    35161 caaaacacca tccagacgcg gataattaac ggcaatgcgc tgtgccagtt gttggcaatt
    35221 ttcggacgtg caggtcagca aatcgagaat aaaccactgt ggctgacgcc cagtttcttc
    35281 gtttatgtgg ctggctacct gacgtaattt ttcttcatta cggcccaaca gaatcactgt
    35341 cgcaccatag cgtgcatacg tcatcgcggc ttcacgacca ataccatcgc tggctcccgt
    35401 caccaggata atgcgatcat tgagtaaatc ttgttttggc tggtaatgca tggctactcc
    35461 tcaacgacgt tgtctgtcgc gctgccagtg tactttatga ctttggggct ttatgcctga
    35521 aacagaaggg catttcaatc agcctggggc gataacaccg caaaatggat actttgtcat
    35581 actttcgctg caataacatc tctgcgagac ggcttaacat gcctgttgta aactgtgagc
    35641 caaagcgttg tttaaccaag gtggggactc gtggaattgt tgtctgaata tggtttgttt
    35701 ttggcgaaaa tcgttaccgt tgtgctagcg attgcggcga ttgccgccat tattgtcaat
    35761 gttgctcaac gtaataaacg ccagcgtggc gagttacggg tcaacaatct cagcgaacag
    35821 tataaggaga tgaaagaaga actggccgcg gcgctgatgg actcacatca gcaaaaacag
    35881 tggcacaaag cgcagaagaa aaagcataag caagaagcga aagcagcaaa agcgaaagcc
    35941 aaactgggcg aggtggcaac tgacagtaaa ccccgcgtct gggtgctgga ttttaaaggc
    36001 agcatggacg cccatgaagt gaactcgcta cgtgaagaga taacggctgt actcgcagca
    36061 ttcaaaccgc aggatcaggt tgtgctccgt ctggaaagcc ctggtggcat ggtgcatggt
    36121 tacgggctgg cggcttcgca actgcagcgt ctgcgcgata aaaacattcc tttaactgtt
    36181 acggtagaca aagtcgctgc cagcggcggt tacatgatgg cctgtgtggc ggacaaaatt
    36241 gtttccgcac cgtttgctat tgtgggttcc attggcgtgg tggcgcaaat gcccaacttt
    36301 aaccgcttcc tgaaaagcaa agatattgat atcgaactgc acactgccgg gcagtataag
    36361 cgcacgctga cgttgctggg tgaaaatacc gaagaagggc gggagaaatt ccgcgaagag
    36421 ttgaacgaaa cgcatcagtt gtttaaagat tttgtgaagc gtatgcgtcc ttctctggat
    36481 attgaacagg tggcaacggg tgaacactgg tacggacaac aggcggtaga gaaaggcctg
    36541 gttgatgaaa tcaacaccag tgatgaagtt attcttagcc tgatggaagg ccgtgaagtg
    36601 gtcaatgtac gctatatgca gcgtaaacga ctcattgacc gattcaccgg cagcgcggca
    36661 gagagcgccg atcgattgtt gctacgctgg tggcagcggg gtcaaaagcc attgatgtaa
    36721 aagacaaacg cgaggctaag acctcgcgtt ttgctttaat caaccagatg atatttttct
    36781 gaaagcacat gggccaggtg tttgaacata ttaaacaccg cggtgctttt ggctgttggc
    36841 aatccttgtt catctaaaaa gtagtcgccg gtaaatacca gcacgccatt acgctgcgtg
    36901 acgccggtgg cttcaatccc tgcgagcgta tcctcatgct cacgaatgat tttgttggcc
    36961 tctttcaaca gcgtttcgcg gtcgatgggt tgtgtctctt tgttcattat ttactcctta
    37021 aacaaggaca ttagtctacg ccaggcatgg cttgcagaca aatataccac gctggtggca
    37081 agagcgcctt actggcaact ttggattttg catgctaata aagttgcgta tcggatttta
    37141 tcaggtacag tgtgacgctt tcgtcaatct ggcaatagat ttgcttgaca ttcgaccaaa
    37201 attccgtcgt gctatagcgc ctgtaggcca agacctgtta actcagtcac ctgaattttc
    37261 gtgaacagag tcacgacaag gggttgatat ccgcagagag cgagtccata tcggtaactc
    37321 gttgccagtg gaaggtttat caacgtgcga cgcattcctg gaagaatcaa attaggtaag
    37381 gtgaatatgg gtaaagctct tgtcatcgtt gagtccccgg caaaagccaa aacgatcaac
    37441 aagtatctgg gtagtgacta cgtggtgaaa tccagcgtcg gtcacatccg cgatttgccg
    37501 accagtggct cagctgccaa aaagagtgcc gactctacct ccaccaagac ggctaaaaag
    37561 cctaaaaagg atgaacgtgg cgctctcgtc aaccgtatgg gggttgaccc gtggcacaat
    37621 tgggaggcgc actatgaagt gttgcctggt aaagagaagg tcgtctctga actgaaacaa
    37681 ctggctgaaa aagccgacca catctatctc gcaaccgacc ttgaccgcga aggggaagcc
    37741 attgcatggc acctgcggga agtgattggg ggtgatgatg cgcgctatag ccgagtggtg
    37801 tttaacgaaa ttactaaaaa cgcgatccgc caggcattta acaaaccggg tgagctgaat
    37861 attgatcgtg ttaatgccca gcaggcgcgt cgctttatgg accgcgtggt ggggtatatg
    37921 gtttcgccgc tgctatggaa aaagatcgct cgtggtctgt ctgccggtcg tgtgcagtcg
    37981 gtggcggttc gcctggtggt cgagcgtgag cgtgaaatta aagcgttcgt gccggaagag
    38041 ttctgggaag tcgatgccag cacgaccacg ccatctggtg aagcgttggc gttacaggtg
    38101 actcatcaga acgacaaacc gttccgtccg gtcaacaaag aacaaactca ggctgcggta
    38161 agtctgctgg aaaaagcgcg ctacagcgtg ctggaacgtg aagacaaacc gacaaccagt
    38221 aaacctggcg ctccttttat tacctctacg ctgcaacaag ctgccagcac ccgtcttgga
    38281 tttggcgtga aaaaaaccat gatgatggcg cagcgtttgt atgaagcagg ctatatcact
    38341 tacatgcgta ccgactccac taacctgagt caggacgcgg taaatatggt tcgcggttat
    38401 atcagcgata attttggtaa gaaatatctg ccggaaagtc cgaatcagta cgccagcaaa
    38461 gaaaactcac aggaagcgca cgaagcgatt cgtccttctg acgtcaatgt gatggcggaa
    38521 tcgctgaagg atatggaagc agatgcgcag aaactgtacc agttaatctg gcgtcagttc
    38581 gttgcctgcc agatgacccc agcgaaatat gactccacga cgctgaccgt tggtgcgggc
    38641 gatttccgcc tgaaagcacg cggtcgtatt ttgcgttttg atggctggac aaaagtgatg
    38701 cctgcgttgc gtaaaggcga tgaagatcgc atcttaccag cagttaataa aggcgatgct
    38761 ctgacgctcg ttgaacttac accagcccag cactttacca agccgccagc ccgtttcagt
    38821 gaagcatcgc tggttaaaga gctggaaaaa cgcggtatcg gtcgtccgtc tacctatgcg
    38881 tcgatcattt cgaccattca ggatcgtggc tacgtgcgag tagaaaatcg tcgtttctat
    38941 gcggaaaaaa tgggcgaaat cgtcaccgat cgccttgaag aaaatttccg cgagttaatg
    39001 aactacgact ttaccgcgca gatggaaaac agcctcgacc aggtggcaaa tcacgaagca
    39061 gagtggaaag ctgtactgga tcacttcttc tcggatttca cccagcagtt agataaagct
    39121 gaaaaagatc cggaagaggg tggtatgcgc ccgaaccaga tggttctgac cagcattgac
    39181 tgcccgactt gtggtcgcaa aatggggatt cgcacagcga gcaccggggt attccttggc
    39241 tgttctggct atgcgctgcc gccgaaagag cgttgcaaaa ccaccattaa cctggtgccg
    39301 gaaaacgaag tgctgaacgt gctggaaggc gaagatgctg aaaccaacgc gctgcgcgca
    39361 aaacgtcgtt gcccgaaatg cggcacggcg atggacagct atctcatcga tccgaaacgt
    39421 aagttgcatg tctgtggtaa taacccaacc tgcgacggtt acgagatcga agagggcgaa
    39481 ttccgcatta aaggttatga cggcccgatc gttgagtgtg aaaaatgtgg ctctgaaatg
    39541 cacctgaaaa tggggcgttt cggtaaatac atggcctgca ccaacgaaga gtgtaaaaac
    39601 acacgtaaga ttttacgtaa cggcgaagtg gcaccaccga aagaagatcc ggtgccatta
    39661 cctgagctgc cgtgcgaaaa atcagatgct tatttcgtgc tgcgtgacgg tgctgccggt
    39721 gtgttcctgg ctgccaacac tttcccgaaa tcgcgtgaaa cgcgtgcgcc actggtggaa
    39781 gagctttatc gcttccgcga ccgtctgccg gaaaaactgc gttatctggc cgatgcgcca
    39841 cagcaggatc cggaaggtaa taagaccatg gttcgcttta gccgtaaaac caaacagcaa
    39901 tatgtctctt cggaaaaaga cggaaaggcg actggctggt cagcatttta tgttgatggc
    39961 aaatgggttg aaggaaaaaa ataaccttta attctgtcag gtttttataa acaaagggtc
    40021 gcgaaagcgg ccctttttta ttgcatatt
//
LOCUS       DAPHKZ010000031        39493 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.031, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000031 DAPHKZ010000000
VERSION     DAPHKZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39493
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.031"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(152..856)
                     /locus_tag="RH288_001708"
     CDS             complement(152..856)
                     /locus_tag="RH288_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDV4030773.1"
                     /translation="MDRFPRSDSIVQPRAGLQTYMAQVYGWMTVGLLLTAFVAWYAAN
                     SAAVMELLFTNRVFLIGLIIAQLALVIVLSAMIQKLSAGVTTMLFMLYSALTGLTLSS
                     IFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
                     LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDTSNLRKYSILGALTLYLD
                     FINLFLMLLRIFGNRR"
     gene            complement(993..1445)
                     /gene="moaE"
                     /locus_tag="RH288_001709"
     CDS             complement(993..1445)
                     /gene="moaE"
                     /locus_tag="RH288_001709"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HDV4030774.1"
                     /translation="MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLG
                     DSVNALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSA
                     HRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW"
     gene            complement(1447..1692)
                     /gene="moaD"
                     /locus_tag="RH288_001710"
     CDS             complement(1447..1692)
                     /gene="moaD"
                     /locus_tag="RH288_001710"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HDV4030775.1"
                     /translation="MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHMAAQSDRWAL
                     ALEDGKLLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG"
     gene            complement(1685..2170)
                     /gene="moaC"
                     /locus_tag="RH288_001711"
     CDS             complement(1685..2170)
                     /gene="moaC"
                     /locus_tag="RH288_001711"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDV4030776.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     IDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
                     D"
     gene            complement(2173..2685)
                     /gene="moaB"
                     /locus_tag="RH288_001712"
     CDS             complement(2173..2685)
                     /gene="moaB"
                     /locus_tag="RH288_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HDV4030777.1"
                     /translation="MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHV
                     VDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            complement(2707..3696)
                     /gene="moaA"
                     /locus_tag="RH288_001713"
     CDS             complement(2707..3696)
                     /gene="moaA"
                     /locus_tag="RH288_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDV4030778.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNK
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNG
                     YRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVK
                     VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELL
                     RRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLF
                     GEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG"
     regulatory      complement(3684..3828)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            4093..5001
                     /gene="yvcK"
                     /locus_tag="RH288_001714"
     CDS             4093..5001
                     /gene="yvcK"
                     /locus_tag="RH288_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HDV4030779.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTP
                     IQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMV
                     YIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVL
                     EASDIPYRHDRQLLHNALEKALQALG"
     gene            complement(5193..7214)
                     /gene="uvrB"
                     /locus_tag="RH288_001715"
     CDS             complement(5193..7214)
                     /gene="uvrB"
                     /locus_tag="RH288_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HDV4030780.1"
                     /translation="MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLE
                     NNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVP
                     MDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(7793..8470)
                     /gene="bioD"
                     /locus_tag="RH288_001716"
     CDS             complement(7793..8470)
                     /gene="bioD"
                     /locus_tag="RH288_001716"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HDV4030781.1"
                     /translation="MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGS
                     EKTPEGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAG
                     LRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTA
                     QVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGK
                     YINLALL"
     gene            complement(8463..9218)
                     /gene="bioC"
                     /locus_tag="RH288_001717"
     CDS             complement(8463..9218)
                     /gene="bioC"
                     /locus_tag="RH288_001717"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HDV4030782.1"
                     /translation="MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYT
                     HVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATA
                     TFDLAWSNLAVQWCGNLSTALRELYRVVRPKGVVAFTTLVQGSLPELHQAWQAVDERP
                     HANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRIL
                     TRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE"
     gene            complement(9205..10359)
                     /gene="bioF"
                     /locus_tag="RH288_001718"
     CDS             complement(9205..10359)
                     /gene="bioF"
                     /locus_tag="RH288_001718"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HDV4030783.1"
                     /translation="MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNF
                     SSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYSRA
                     LLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLAR
                     LLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRG
                     SCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQAL
                     RASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQL
                     AEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG"
     gene            complement(10356..11396)
                     /gene="bioB"
                     /locus_tag="RH288_001719"
     CDS             complement(10356..11396)
                     /gene="bioB"
                     /locus_tag="RH288_001719"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDV4030784.1"
                     /translation="MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAW
                     KNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMT
                     PDTDEYYNAAAL"
     gene            11483..12772
                     /gene="bioA"
                     /locus_tag="RH288_001720"
     CDS             11483..12772
                     /gene="bioA"
                     /locus_tag="RH288_001720"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HDV4030785.1"
                     /translation="MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRR
                     LVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQP
                     LECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNS
                     MHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAG
                     GMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKAL
                     TGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQ
                     QVADIEVQLREQLAPARDAEMVADVRVLGAIGVVETTHPVNMAALQKFFVEQGVWIRP
                     FGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ"
     gene            12831..13307
                     /locus_tag="RH288_001721"
     CDS             12831..13307
                     /locus_tag="RH288_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HDV4030786.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTG
                     YDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS"
     gene            13459..14742
                     /locus_tag="RH288_001722"
     CDS             13459..14742
                     /locus_tag="RH288_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HDV4030787.1"
                     /translation="MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPI
                     LSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVD
                     AAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
                     DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVT
                     NSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFN
                     AFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVD
                     DNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK"
     gene            complement(14976..17237)
                     /locus_tag="RH288_001723"
     CDS             complement(14976..17237)
                     /locus_tag="RH288_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydratase"
                     /protein_id="HDV4030788.1"
                     /translation="MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSS
                     HNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGT
                     INGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
                     AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVK
                     NKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQL
                     NPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAH
                     GKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
                     SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREG
                     SKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQG
                     FVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRS
                     NPIGLAEFTLSRRDPGYVSRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPL
                     QTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQM
                     AEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIK
                     AGSLINFNKNRQM"
     gene            complement(17420..18853)
                     /locus_tag="RH288_001724"
     CDS             complement(17420..18853)
                     /locus_tag="RH288_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HDV4030789.1"
                     /translation="MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIV
                     GLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAA
                     FVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
                     AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISW
                     GGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLG
                     VFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGII
                     GLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAML
                     PVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGA
                     VLTILTFLVHITLGVWWWNMLIGWNML"
     gene            complement(18929..19981)
                     /locus_tag="RH288_001725"
     CDS             complement(18929..19981)
                     /locus_tag="RH288_001725"
                     /EC_number="5.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalomesaconate tautomerase"
                     /protein_id="HDV4030790.1"
                     /translation="MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGND
                     LEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGA
                     FAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVA
                     LTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELD
                     ADKALLARIESIRLQAGKTMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRA
                     LAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRAS
                     VIRTTRKIFSGEVYLP"
     gene            20165..21117
                     /locus_tag="RH288_001726"
                     /pseudo
     CDS             20165..21117
                     /locus_tag="RH288_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308823.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(21158..22153)
                     /gene="pgl"
                     /locus_tag="RH288_001727"
     CDS             complement(21158..22153)
                     /gene="pgl"
                     /locus_tag="RH288_001727"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HDV4030791.1"
                     /translation="MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYN
                     AGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG
                     HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTL
                     DMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ
                     PRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH"
     gene            22308..23126
                     /gene="ybhA"
                     /locus_tag="RH288_001728"
     CDS             22308..23126
                     /gene="ybhA"
                     /locus_tag="RH288_001728"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyridoxal
                     phosphate/fructose-1,6-bisphosphate phosphatase"
                     /protein_id="HDV4030792.1"
                     /translation="MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTG
                     RHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHI
                     HGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
                     THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENV
                     VAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI"
     gene            complement(23127..24185)
                     /gene="modC"
                     /locus_tag="RH288_001729"
     CDS             complement(23127..24185)
                     /gene="modC"
                     /locus_tag="RH288_001729"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HDV4030793.1"
                     /translation="MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAI
                     SGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMS
                     KSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWG
                     SSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELA
                     IKPGLWLYAQIKSVSITA"
     gene            complement(24188..24877)
                     /gene="modB"
                     /locus_tag="RH288_001730"
     CDS             complement(24188..24877)
                     /gene="modB"
                     /locus_tag="RH288_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDV4030794.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEW
                     LARISRERAGR"
     gene            complement(24877..25650)
                     /gene="modA"
                     /locus_tag="RH288_001731"
     CDS             complement(24877..25650)
                     /gene="modA"
                     /locus_tag="RH288_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV4030795.1"
                     /translation="MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDI
                     ATQFKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQ
                     TLLGNSLVVVAPKASVQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
                     GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKV
                     EYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTIK"
     gene            complement(25817..25966)
                     /gene="acrZ"
                     /locus_tag="RH288_001732"
     CDS             complement(25817..25966)
                     /gene="acrZ"
                     /locus_tag="RH288_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump accessory protein AcrZ"
                     /protein_id="HDV4030796.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQ
                     PGQNH"
     gene            26095..26883
                     /gene="modE"
                     /locus_tag="RH288_001733"
     CDS             26095..26883
                     /gene="modE"
                     /locus_tag="RH288_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HDV4030797.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDV
                     LSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
                     AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCE
                     VLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC"
     gene            26951..28423
                     /gene="modF"
                     /locus_tag="RH288_001734"
     CDS             26951..28423
                     /gene="modF"
                     /locus_tag="RH288_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HDV4030798.1"
                     /translation="MSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSA
                     LARALAGELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTT
                     AEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
                     EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGA
                     KEELLQQALVAQLAHSEQLEGVQLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPIL
                     NNLSWQVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISE
                     GETQLLFVSHHAEDAPACITHRLEFVPDGGLYRYVLTKIY"
     gene            28684..29700
                     /gene="galE"
                     /locus_tag="RH288_001735"
     CDS             28684..29700
                     /gene="galE"
                     /locus_tag="RH288_001735"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415280.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDV4030799.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVN
                     GTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAF
                     SKACGKPVNYHFAPRREGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYPD"
     gene            29710..30756
                     /gene="galT"
                     /locus_tag="RH288_001736"
     CDS             29710..30756
                     /gene="galT"
                     /locus_tag="RH288_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDV4030800.1"
                     /translation="MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQV
                     LPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESHDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQIWANSFLPNEAEREDRLQKEYFAEQKSPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            30760..31908
                     /gene="galK"
                     /locus_tag="RH288_001737"
     CDS             30760..31908
                     /gene="galK"
                     /locus_tag="RH288_001737"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDV4030801.1"
                     /translation="MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKH
                     LQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAYELDPIVAKRVRHILTENARTV
                     EAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGG
                     GFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC"
     gene            31902..32942
                     /gene="galM"
                     /locus_tag="RH288_001738"
     CDS             31902..32942
                     /gene="galM"
                     /locus_tag="RH288_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HDV4030802.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPECYQDQAAFLGASIGRYANRIANSRYTFDGETVTLSPSQGVNQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
                     RATVDKPCPVNMTNHVYFNLDGEQSDVRNHKLQILADEYLPVDEGGIPHDGLKSVAGT
                     SFDFRSAKIIASEFLADDDQRKVKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYT
                     TAPALQFYSGNFLGGTPSRGTEPYADWQGLALESEFLPDSPNHPEWPQPDCFLRPGEE
                     YSSLTEYQFIAE"
     gene            33144..33896
                     /gene="gpmA"
                     /locus_tag="RH288_001739"
     CDS             33144..33896
                     /gene="gpmA"
                     /locus_tag="RH288_001739"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDV4030803.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEF
                     DENFKPLKRYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(34054..35106)
                     /gene="aroG"
                     /locus_tag="RH288_001740"
     CDS             complement(34054..35106)
                     /gene="aroG"
                     /locus_tag="RH288_001740"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HDV4030804.1"
                     /translation="MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAGLPAQVMIDFSHANSSKQFK
                     KQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAYGKSITDACIGWEDT
                     DALLRQLANAVKARCG"
     gene            35422..35802
                     /locus_tag="RH288_001741"
     CDS             35422..35802
                     /locus_tag="RH288_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HDV4030805.1"
                     /translation="MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQ
                     VAPDARENVAPNNVDNNGVNTGSGGTMLHSDGSSMNNDGMTKDEEHKNTMCKDGRCPD
                     INKKVQTGDGINNDVDTKTDGTTQ"
     gene            35916..36857
                     /gene="zitB"
                     /locus_tag="RH288_001742"
     CDS             35916..36857
                     /gene="zitB"
                     /locus_tag="RH288_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HDV4030806.1"
                     /translation="MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGS
                     LALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVIT
                     ILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
                     LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPV
                     SLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYL
                     MDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH"
     gene            complement(36854..37573)
                     /gene="pnuC"
                     /locus_tag="RH288_001743"
     CDS             complement(36854..37573)
                     /gene="pnuC"
                     /locus_tag="RH288_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HDV4030807.1"
                     /translation="MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEK
                     ISNYFFGLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELKIR
                     WLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVVMPELQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIA
                     LNGSRMWINSARERGSRALSH"
     gene            complement(37611..38654)
                     /gene="nadA"
                     /locus_tag="RH288_001744"
     CDS             complement(37611..38654)
                     /gene="nadA"
                     /locus_tag="RH288_001744"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDV4030808.1"
                     /translation="MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK
                     TILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEY
                     PDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHEVHVDERLRERALVP
                     LNRMLDFAATLRG"
     gene            complement(38932..39007)
                     /locus_tag="RH288_001745"
     tRNA            complement(38932..39007)
                     /locus_tag="RH288_001745"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38972..38974),aa:Lys,seq:ttt)
     gene            complement(39140..39215)
                     /locus_tag="RH288_001746"
     tRNA            complement(39140..39215)
                     /locus_tag="RH288_001746"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39180..39182),aa:Lys,seq:ttt)
     gene            complement(39362..39437)
                     /locus_tag="RH288_001747"
     tRNA            complement(39362..39437)
                     /locus_tag="RH288_001747"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39402..39404),aa:Lys,seq:ttt)
BASE COUNT         9663 a        10480 c         9908 g         9442 t
ORIGIN      
        1 accacgcata caaaatactt ttgcatttat ggatacagaa aacgcttccg ctcgtccata
       61 aggcatattt tatacctggt acttgttaag tgtcgttttt agtaagaaaa aaatcccgac
      121 acatggccgg gatagtgatg gtgaaaaaga attaacggcg gttgccgaag atccgcaaca
      181 acatcaggaa caggttgatg aagtccagat acaaggttaa cgcgccaaga atggaatatt
      241 tgcgcaggtt cgacgtgtcg cgggtatcaa tctgctcacc catatttttc agtttctgcg
      301 tgtcatacgc cgtcaatccg acaaagacaa tcacgccgat gtaggtaact gcccacatca
      361 atgcttcgct tttcaaccag aagttgacca gcgatgccag cacaatgccg attaacgcca
      421 taaacagcat attgccaaag ccacttaaat cgcgcttcgt ggtgtaaccg tacaggctca
      481 ttgcgccgaa catcccggca gtaacgacga aagtactggc gatagaagca gcggtataga
      541 caatgaatat actggaaagc gtaagacccg tcagcgccga ataaagcata aagagcatcg
      601 tcgttacacc tgcgctcagc ttttgaatca tcgctgataa cacaataacc aatgctaatt
      661 gcgcgatgat cagaccgatt aaaaagacac ggttagtgaa caacagctcc atcacggccg
      721 cggaattagc cgcataccag gcaacaaatg cggtcagcaa caagccaacg gtcatccagc
      781 catagacttg agccatataa gtttgcaagc cagcccgggg ttgtacgatt gaatcagaac
      841 gtgggaatct gtccatgacg atctcctgaa gatataagga atatcttaag gatactgcaa
      901 aatgatgagg ctgtgcatcg acgcagcgta aacgtatgta ctgagcggtg aaattgccgg
      961 acgcagcggt gccttatccg gctaacaaaa aactaccagc gttttgccgc ctgctgatcg
     1021 ctctcccgag cttcaaccca gcggtcgcct tccggcgtgg cttcgcgctt ccagaacggt
     1081 gcgcgggttt tgagataatc cataataaac tgcccggctt caaacgcact gctgcgatgc
     1141 gcactggtga caccgacaaa aacgatttca tcgcccggcc ataattcccc gatgcggtga
     1201 atcacagtga cgcgccccag cggccagcgg ttacgcgctt catcaacaat ttctgccagt
     1261 gctttttcag tcatccccgg atagtgttcg agggttaatg cgttgacgct gtcgcccagg
     1321 ttatggttgc gcaccttacc agtaaaggtg actaccgcac cgtcttcgtc acgctccgcc
     1381 agccacgggt actcttctcc tacgctgaac ggctgcggac caacaacaat tttggtttct
     1441 gccatcttaa cctccggtta ccggcgggaa gaaagctact tcgtcgccgt cagtcagcgg
     1501 atggtcaaaa ctcaccagcg tctggttgac ggcagccagt aatttgccat cttccagcgc
     1561 cagcgcccag cgatcgctct gcgcagccat gtgctggcgt aacgcttcaa cagttgggaa
     1621 atccgcagcc acttcggttg catctgttcc caccaactcg cgcacctggg cgaaaaaaag
     1681 aactttaatc atccgcttcc accttaaagt cacccgactt gccgccgctc ttcgccagca
     1741 aacgtaccgg accaatcacc atatcttttt gcaccgcttt gcacatgtca taaatggtca
     1801 gcgccgccac ggaggccgcg gttaatgctt ccatttcgac accggttttc ccggtcaggc
     1861 ggcataaggt ttctatacgc acccgattgt gctccggctc ggcctgtaaa ttgacttcaa
     1921 ctttgctgag catcagcgga tgacagagcg ggatcagatc ccaggtgcgt tttgccgcct
     1981 gaataccggc aatacgcgca gtggcaaata cgtcgccttt gtggtggcga ccatcaataa
     2041 tcatcgccag cgtctcgctg cgcatggtga caaaggcttc cgcccgcgct tcacgcacgg
     2101 tttccgcttt ggcggagaca tccaccatgt gcgcttcgcc agcggcgttg atatgggtca
     2161 gttgcgacat acttatttct tcaaatgtgg atggaaatta cacggacgcg tacgggcatc
     2221 cagctgcggc gcgatgatat tttcccatgc ggtacggcac gctttggtcg aacccggcat
     2281 ggcgaaaatc agcgttttgt tggcgacgcc cgctaccgca cgagattgca acgtggaagt
     2341 gccaatctct tcaaacgaca acatccggaa cacttcacca aaaccttcaa cttcacggtc
     2401 gaacaacggc agcaatgctt cgggagcctg atcaccttcc gtcaggccag taccacccgt
     2461 aatcaatacc acttgtacat cgtcgctggc gatccacgca gatacctgag cgcgaatagc
     2521 gtagcggttt tctttcacaa tggctttatc gacaacgtga tggcccgctt cttgcgccga
     2581 atcgcgcaga tagtgaccgg aggtatcgtc ttcttcaccg cgacgattag aaaccgtaag
     2641 aatagcaata cgggtcggga taaattcagt gcttacctga ctcatctgat ctctcctttt
     2701 gacgttttag ccgccaatgt acgataagtt ttgcgtaata ccggtgttgt tttgatgcag
     2761 gaaatgggtc tgtttcttct cccgcagcgc cgctgaaata cgcgcttcca gcgcctgttg
     2821 ctgggtatcg tcttccagca gatcgcgcag gttaacgccg ccttcaccaa acaggcagag
     2881 atggagttta ccaatggagg aaacgcgcag gcggttgcaa gtggcgcaga agtctttttc
     2941 atacggcatg ataaggccaa tctctccggc gtaatctgga tggcaaaaga cttgcgcggg
     3001 accgtcgctg cgttgacgta attggtggat ccagccgcga cgcagtagct cgtcacgcag
     3061 aacctgacca gagatgtgat gcttacggaa gagctcgctg ccctcgcccg tttccatcag
     3121 ttcgatgaaa cgcagctgga tagggcgatg ctggatccag ttcagaaagg tgtcgagctg
     3181 gtgatgatta acatcacgca tcagcacggt attgactttg accttctcaa aaccggcctc
     3241 aaatgcagca tcaatccctg ccatgacctg gttgaattta tcctgcccgg taatagcgtg
     3301 aaactggcgg gcgtccagac tgtcgacact gacgttaatg ccagtaagtc ccgcatcgcg
     3361 ccagctcgcc acatcgcgtt ccagacggta accattggtt gtgaccgcaa tctggcggat
     3421 agcgtcgttt tcccgcacag cggcgatgat atcggtaaag tcgcggcgta aagacggctc
     3481 tcctcctgtc aggcgcactt tttcggtgcc cagactggcg aaggcgcgcg taacccggcg
     3541 aatttcatcg acggtaagaa agcctttatt ggtgacgccg ctcggtttgt agccatccgg
     3601 caggcagtag gtgcaacgaa agttacacac atcggtaatc gacaggcgca agtagtaaaa
     3661 cttacgcgca aatgcatcag tcagttgtga agccatgtac acctttccag atacgggagg
     3721 cgaagtcatt tcttccttcg ccctggtggc aatctttacg agcattgtca cggccaaagc
     3781 accgtatcag ttgacccagg tgcagaggct agagtgttta gtggttatgc cgatactagc
     3841 gtgtaaatga gatttttacc atccacactt tcgctatgta atcatgtata tagcgtcatg
     3901 atcgtgctat ttcgctacag aataagggaa aatggcggtt ttactttgat atacatcatc
     3961 agggaggcat agcgtgcatc gtcctttaga ggtagaagaa aatagtttgt atcctcaata
     4021 ttggcaggtt aattgctgtt tccccgcaat ttgcgctact gtagcgcgga taatctgact
     4081 ccaggaaact atatgcgcaa tcgtacgctg gctgatcttg atcgtgtcgt tgctctcggc
     4141 ggagggcatg gactgggacg cgttctctca tcactttcgt ctttgggttc tcgtttaacg
     4201 ggtatcgtca ccaccaccga taatggtggc tcgacggggc gtattcgccg ttcagaaggc
     4261 ggcattgcct ggggcgatat gcgcaactgc ctcaaccagc tgataacgga accgagcgtc
     4321 gcctccgcga tgtttgaata ccgttttggt ggcaatggcg aactttccgg tcataatctc
     4381 ggaaacttga tgttaaaggc gctggatcac cttagcgtgc ggcctctgga agccatcaat
     4441 ttaattcgta atctgctgaa agtggatacg catttgattc caatgtcaga gcatcctgtt
     4501 gatctgatgg cgattgacga tcaggggcat gaagtttacg gcgaggtcaa tatcgaccag
     4561 ttaactacgc cgattcaaga gttattgtta acgcctaatg tacccgcaac gcgtgaggcg
     4621 gttcacgcta tcaatgaagc ggatctcatc attattgggc ctggcagttt ttataccagc
     4681 ctgatgccaa ttctgctgct gaaggaaatc gcccaggcat tacgccgcac gccagcgccg
     4741 atggtttata tcggcaatct ggggcgtgag ttgagtttac ctgcggctaa tttgaagctg
     4801 gaaagcaagc tggcaattat ggagcagtat gttggtaaaa aggtcattga tgcggtcatc
     4861 gtcgggccaa aagtggatgt ctcggcggtg aaagagcgga ttgtgatcca ggaggtactg
     4921 gaggccagcg atattccgta tcgtcatgac cgccagttgt tacataacgc gctggaaaag
     4981 gcgttacagg ctttaggtta acggaaatcc gaaggaaaat tccggcttcc tattgaagac
     5041 aaagtgcgcg ttgtttatgc cggatgcggc gtgaacgcct tatccggcct acaaaccgcg
     5101 caaattcaat atattgcgga gaaaatgtag gcctgataag cgtagcgcat caggctgttt
     5161 tccgtttgtc atcagtcttc ttcgctatcc tgttacgatg ccgcgataaa cagctcacgc
     5221 agctgatgca actggtcacg aatttgcgcc gcttcttcga actccagatt ctgcgcgtgt
     5281 tgcatcatca acccttccag ctcatggatt ttctgctgca acgctttagg cgacatatcc
     5341 atcggcacat tatccggctc aacaatcggg cgcgattttc ctctgccctt cgctttggtt
     5401 ttggcaatgt tctgccccag cgccaggata tcgaccactt tcttgttcaa gccttgcggc
     5461 gtaattccgt gttcctcgtt gtacttctgc tgtttctcac ggcgacgttc ggtttcgcca
     5521 atcgctttcg ccattgatgg ggtgatctta tcgccgtaga gaatcgcttt accgttaacg
     5581 ttacgtgccg cacgaccaat ggtctggatc aacgaacgtt cggaacgcag gaagccttct
     5641 ttgtcagcgt cgaggatcgc caccagcgac acttccggca tatccagacc ttcgcgcagt
     5701 aagttgatcc ctaccagcac gtcgaactca cccagacgca agtcgcggat aatctccata
     5761 cgttcgacgg tgtcgatatc tgagtgaaga taacgcacgc gctcgccatg ttcttcgaga
     5821 tattcggtaa gatcttccgc catccgcttg gtcagtgtgg tgaccagtac gcgttcgtta
     5881 attgccgctc gctgacgaat ctccgaaaga agatcatcaa cctgtgtcgc caccggccgc
     5941 acttcgataa tcgggtcaag caatccggtt ggacgcacca cctgatccac cacatcgccg
     6001 ccggattttt ccagctcgta attacccggc gtcgccgaaa catagatggt ttgcggcgct
     6061 aatgcttcga actcttcaaa cttaagcgga cggttatcca gcgctgatgg caggcggaag
     6121 ccgtactcca ccagtgtctc tttacgcgcc cggtcaccgc gatacatgcc gccaatttgt
     6181 ggaatggtga cgtgagattc atcgacgacc agcagcccat cggcaggcag gtaatcaaac
     6241 agcgtcggcg gtggctcacc cggtccacga ccggagagga agcgcgagta gttttcaatc
     6301 cccgaacagt agcccagctc gttcatcatc tccagatcaa actgggtacg ctgggtcagc
     6361 cgctgctctt ccagcagttt gttgttttcc aacagcactt tgcgtctggc ggccagctct
     6421 tctttgatct cctccatcgc ctgtacgatg cgctcgcgcg gtgtgacgta gtgcgttttc
     6481 gggtagatgg taaaacgtgg aatagtggaa acaatctgcc cggtcagcgg gtcaaataac
     6541 gacaatcgtt ccacttcctc gtcaaacagt tccacgcgaa gtgcaatgtc atccgattct
     6601 gccgggaaga tatctatcac ctcgccacga acgcggaaag taccacgctg gaatgcttga
     6661 tcattacgag cgtattgcag ctccgccagt cggcgcagaa tcgcgcgctg atcgataatc
     6721 ataccgaccg tgagatggag catcatcttg agatataaat caggatcgcc cagaccataa
     6781 atcgcggaaa cagacgccac cacaaccaca tcacgccgct ccagcatcgc tttggtggcg
     6841 gacaaacgca tctgctcaat atgttcgtta accgaggcat ctttctcaat gaaagtgtcg
     6901 gaactcggta cataggcttc cggctgatag tagtcgtagt aggaaacgaa atattccacc
     6961 gcgttttccg ggaagaactc tttcatttcg ccatacagct gggccgccag cgttttgttg
     7021 ggcgcaagta ccatggttgg gcgctgaagg tcagcaatga cattggcaat ggtgaaggtt
     7081 ttccctgagc cagtcacgcc aagtaacgtc tggtgcgcca ggccatcttc cagcccctct
     7141 tcgagacgtc gaatcgcctc tggctgatcg ccagaaggtt taaaagcgga attcagtttg
     7201 aacggtttac tcatgagtcg ctacctgaag gagttgggcg ggcaggtatg taattttact
     7261 cgtcgtactt aattatgcca acaaattata ctggataaaa aaacagttca tcaccataat
     7321 atttctgata cagcgtaaac tccgctgtca atcatgagca aaatttactc tgtggcgaga
     7381 taaaactccg gccttaccgg gttatcccca aagcaacggc ttttttaaca tttgtcaaga
     7441 tgagtgatga cagttttatg gcaagagatg cctgttcagt gactgccatt gcatttatct
     7501 aaccagttaa aaaataaaag atatttcttt gagccgtctt taacgccaat tcgcgtgcaa
     7561 gccgcgtatt ctctcgcttg cctcgtgttt tctaactcta atacacatgg ttatccacag
     7621 gaatagtgga taactgtctc cagcccctat cccccgccgc ctgggcaatt cccacattcg
     7681 ccgcatgagg cggaagtaaa atttttttcg tgattatttt agaatttaat tggttaaatt
     7741 gcagtcaatc gaagacgcga tctcgctcgc aatttaacca aatacagaat ggctacaaca
     7801 aggcaaggtt tatgtacttt ccggttgccg cattttctgg attttctgca agccagggga
     7861 tctctcccag cagcggcgcg ggaatcatgc gggtgagcgt ggtcatatat tcagcgtgac
     7921 gttttcccgg aggcgtaaca tcgttcgcca cccaacccgc cagagtcagt ccggcgtgtt
     7981 gtattacctg tgcagtcaac atcgcgtgat taatacagcc gagtttcaca ccaactacca
     8041 gtatcaccgg cagttgttcc tgtgttaccc aatctgcaaa agtgaaagtg tcagaaagcg
     8101 gcgtaaacca gccgccagca ccttccacta acacccagtc agcctgttgt tcaagcgcgc
     8161 gtaatccggc gctcattacc aatgattcta tcggtctgcc ctcttgcgcg ctgatgatgt
     8221 gcggcgaagt gggttctgcg aaggtgtaag gatttactgt tgcgtaatcc agctgcaggc
     8281 tgctgttgcg ctgtaacgcc agcgcgtcgc tattgcgtaa accttccggg gtcttttcgc
     8341 tgccagaggc gaccggttta taacctgccg tccggtagcc tgctgccttt gcggcttgta
     8401 aaagtgcaca actggcgaca gttttcccca cttcggtatc cgttccggtg acaaaataac
     8461 gtttactcac gagcaatcac tcccaaaaaa agatgatacg tcagaggata tcgcccctgc
     8521 tgttgcggcc aggccagttg caatcgctgc aactgcgaac gcgttaatat tcgcgggtcg
     8581 cgcccttcat gaagatgcgt ggcaccgatg cctttcagcg aacgcatggc actgagcgca
     8641 tcatcaaacc acagcgtgat gggctgaata tgatgttgat aatgcacgcc gttcagcgac
     8701 tgttcgattt catctggcgg taaaaagcga ttagcatgcg gacgctcgtc caccgcctgc
     8761 cacgcctgat gcagttcggg taacgatccc tgcaccagcg tggtaaacgc gaccacgcct
     8821 ttggggcgca ccacccgata cagctcgcgg agtgccgtgg ataaattacc gcaccactgc
     8881 actgcgagat tgctccatgc aagatcgaac gtcgcagtcg ctaacggcag ggattcgata
     8941 tctcccgcca gataatggtc tgcggcatcc ttctggcgtg cctgaacaag cattggcggc
     9001 gagagatcta aggccgtcac ctgcgcgtga cgttcccgcc agtggcggct catccagcca
     9061 ggtccacaac ccgcgtccag tacgtgggtg tatttacgct gtggaagcat tgccagtaag
     9121 gcgtcagcac tctggcgctg tagatctgca tgttgctcat agtgtgcggc tgcccgacca
     9181 aatgccgctg caatggcttg tttattaacc gttgccatgc agcacctcca gcagacggtc
     9241 gatatcctgc atttcatgcg cagcggttag cgttaagcgc agtcgcgcag taccagcggg
     9301 tacggttggc gggcgaatcg ccgtgaccca gcagccttgc tggcgcagtt tttctgccag
     9361 ttgtaacgca cggctgttat caccgacaat caatggctgg atggcgctgc atgaatcagc
     9421 aagcgtaaac ggcaaatcct gtactccggc acgaaaacgc gtaatgagtg ccgccagttt
     9481 ttcgcgccgt gcatcaccct catcactgcg aatgaccgcc agcgacgcac gtaatgcctg
     9541 cgcctgagcg ggcggcatac tggtgctgta gataaggtgg cgggcgaatt gcagcagata
     9601 atccgccacc gtactggagc aaagcaccgc tgccccgctg acgccaaatc ctttgccaaa
     9661 agtcactacc agcaattctg gttttacctt ttgcagccag cagctgccgc gcccctgctc
     9721 cccgataacg cccgtgccgt gggcatcatc gaccatcaac cagccattgt gctgttgcgt
     9781 tacctgctgg atttccgcca gtggcgcact atcgccgtcc atgctgaaca cgccttctgt
     9841 caccaccatt tgctgccccg gacaggggga agcaagcaat cgcgccaaat gagtgacatc
     9901 gttatgagca aaacggcgaa gctgcgacgg gcttaaactg gcagcttcca gcaatgaggc
     9961 atggctaagc cggtcggcag caatacggtc ctctttcgcc atcatcgcgg caataactgc
    10021 ctgattagcg gcgaaaccag agataaacag cagtgcccgc gaatagccaa gccactcggc
    10081 cagctcttct tccagtgcct gatgcaccac gctataaccg ctgacgtgac cggagccgcc
    10141 gctaccgatg ccaaattgct ccgccccctg ctgccaggca cggataattt gcggatgatg
    10201 gcttaaacct aaataatcgt tactggaaaa gttcagatac tggcgatcat ccgccaccag
    10261 ccagcgtccg gctccttgcg ccaccggata acggcgacgc agggcatcgg cagcacgccg
    10321 cgcatcgagc gccgcgttga ttttctcctg ccagctcata atgctgccgc gttgtaatat
    10381 tcgtcggtgt ccggggtcat cagcgcctgt tcaagacgtt gctgttgttc gttatcccct
    10441 gccagcacgg cagtttgctg cggatttagc cccagtttgc ggaacagttg caggtcttta
    10501 tcttcttccg gattcggcgt ggtcagcagt ttgcaaccgt agaaaatcga gtttgcgcct
    10561 gccataaagc acatcgcctg agtctgttcg ttcatctgct cgcgtccggc agaaaggcgc
    10621 acgtaagagg ttggcatcat gatccgcgcg accgcaatgg tgcgaataaa atcaaaggca
    10681 tcgacatcat cgttatcggc aagcggcgtg cctttcacct tcaccagcat gttgattggc
    10741 acgctttccg gcggcgtcgg caggtttgcc agttgcagca ataatccggc gcgatctttt
    10801 accgtttcgc ctaagcccac aatgccgcca gaacagactt tgatcccggc atcgcgcact
    10861 ttttccagcg tatcgaggcg ttcctgataa gtgcgtgtgg tgatgatatt gccgtaaaac
    10921 tccggcgagg tgtccaggtt gtggttgtag taatccagcc cggcgttcgc gaggcgctgc
    10981 gcctgagatt cactcaacgt gcccagcgtc atacacgcct ccagccccat cgcttttacc
    11041 ccctgcacca tttgttccag gtacggcata tcgcgttcgt ggggattctt ccacgccgcg
    11101 cccatacaga agcgcgtcga tcctgccgct ttcgctttgc gcgccgactc cagcacctgt
    11161 tcaacttcca tcaaccgctc ggcttccagc ccggttttgt agcgcgagct ttgcgggcag
    11221 tatttgcaat cttccggaca agctccggtc ttaatcgaca gcaacgtgct gacctgcacc
    11281 tgacgaggat cgaaatgctg gcgatgcacc tgctgcgctt caaacagcag atccagcaac
    11341 ggtttttcaa ataattctgt gacttgcgac aatgtccagc gtgggcggtg agccatgggg
    11401 cttctccaaa acgtgttttt tgttgttaat tcggtgtaga cttgtaaacc taaatctttt
    11461 caatttggtt tacaagtcga ttatgacaac ggacgatctt gcctttgacc aacgccatat
    11521 ctggcaccca tacacatcca tgacctcccc tctgccggtt tatccggtgg tgagcgccga
    11581 aggttgcgag ctgattttgt ctgacggcag acgcctggtt gacggtatgt cgtcctggtg
    11641 ggcggcgatc cacggctaca atcacccgca gcttaatgcg gcgatgaagt cgcaaattga
    11701 tgccatgtcg catgtgatgt ttggcggtat cacccatgcg ccagccattg agctgtgccg
    11761 caaactggtg gcgatgacgc cgcaaccgct ggagtgcgtt tttctcgcgg actccggttc
    11821 cgtagcggtg gaagtggcga tgaaaatggc gttgcagtac tggcaagcca aaggcgaagc
    11881 gcgccagcgt tttctgacct tccgcaatgg ttatcatggc gatacctttg gcgcgatgtc
    11941 ggtgtgcgat ccggataact caatgcacag tctgtggaaa ggctacctgc cagaaaacct
    12001 gtttgctccc gccccgcaaa gccgcatgga tggcgaatgg gatgagcgcg atatggtggg
    12061 ctttgcccgc ctgatggcgg cgcatcgtca tgaaatcgcg gcggtgatca ttgagccgat
    12121 tgtccagggc gcaggcggga tgcgcatgta ccatccggaa tggttaaaac gaatccgcaa
    12181 aatatgcgat cgcgaaggta tcttgctgat tgccgacgag atcgccactg gatttggtcg
    12241 taccgggaaa ctgtttgcct gtgaacatgc agaaatcgcg ccggacattt tgtgcctcgg
    12301 taaagcctta accggcggca caatgaccct ttccgccaca ctcaccacgc gcgaggttgc
    12361 agaaaccatc agtaacggtg aagccggttg ctttatgcat gggccaactt ttatgggcaa
    12421 tccgctggcc tgcgcggcag caaacgccag cctggcgatt ctcgaatctg gcgactggca
    12481 gcaacaggtg gcggatattg aagtacagct gcgcgagcaa cttgcccccg cccgtgatgc
    12541 cgaaatggtt gccgatgtgc gcgtactggg ggccattggc gtggtcgaaa ccactcatcc
    12601 ggtgaatatg gcggcgctgc aaaaattctt tgtcgaacag ggtgtctgga tccggccttt
    12661 tggcaaactg atttacctga tgccgcccta tattattctc ccgcaacagt tgcagcgtct
    12721 gaccgcagcg gttaaccgcg cggtacagga tgaaacattt ttttgccaat aacgagaagt
    12781 ccgcgtgagg gtttctggct acactttctg caaacaagaa aggagggttc atgaaactca
    12841 tcagtaacga tctgcgcgat ggcgataaat tgccgcatcg tcatgtcttt aacggcatgg
    12901 gttacgatgg cgataatatt tcaccgcatc tggcgtggga tgatgttcct gcgggaacga
    12961 aaagttttgt tgtcacctgc tacgacccgg atgcgccaac cggctccggc tggtggcact
    13021 gggtagttgt taacttaccc gctgataccc gcgtattacc gcaagggttt ggctctggtc
    13081 tggtagcaat gccagacggc gttttgcaga cgcgtaccga ctttggtaaa accgggtacg
    13141 atggcgcagc accgccgaaa ggcgaaactc atcgctacat ttttaccgtt cacgcgctgg
    13201 atatagaacg tattgatgtc gatgaaggtg ccagcggcgc gatggtcggg tttaacgttc
    13261 atttccactc tctggcaagc gcctcgatta ctgcgatgtt tagttaatca ctctgccaga
    13321 tggcgcaatg ccatctggta tcacttaaag gtattaaaaa caactttttg tctttttacc
    13381 ttcccgtttc gctcaagtta gtataaaaaa gcaggcttca acggattcat ttttctattt
    13441 catagcccgg agcaacctgt gaacacattt tcagtttccc gtctggcgct ggcattggct
    13501 tttggcgtga cgctgaccgc ctgtagctca accccgcccg atcaacgtcc ttctgatcaa
    13561 accgcgcctg gtacctcttc tcgcccgatt ctgtcggcaa aagaagcgca gaatttcgat
    13621 gctcaacact attttgcatc cctgacacca ggtgctgcag cgtggaatcc ttccccgatt
    13681 accctgcctg cgcaacctga ctttgttgtc ggcccggcgg gcactcaagg tgtaacgcat
    13741 accacgattc aggcggcggt agatgcggca attatcaagc gtaccaacaa gcgccagtat
    13801 attgccgtga tgcctggtga gtatcaggga acggtatatg tccctgccgc tccgggtgga
    13861 attactctgt acggtacagg tgaaaaaccg attgatgtga agattgggct ttcccttgat
    13921 ggtggcatga gccctgccga ctggcgtcac gacgtcaacc cgcgcggcaa atatatgcca
    13981 ggtaaaccag cgtggtatat gtacgatagc tgccagagca aacgcagcga cagtatcggt
    14041 gttctctgct ctgcggtctt ctggtcacaa aacaatggcc tgcaactgca aaatctgacc
    14101 atcgaaaaca cgctgggcga tagcgtagat gcaggtaacc atccggcggt ggcactgcgt
    14161 actgatggtg accaggtaca gattaacaac gttaacattc tcggtcgtca gaacaccttc
    14221 tttgtcacca acagcggtgt gcagaaccgt ctggaaacga atcgtcagcc gcgtacgctg
    14281 gtgaccaaca gctacattga aggggatgtg gatatcgttt ctggtcgcgg cgcagtggtg
    14341 ttcgataaca ccgaattccg cgtggtgaac tcacgtactc agcaagaagc gtatgtgttt
    14401 gcaccggcta cgctgtccaa catttactac ggtttcctcg ccgtaaacag ccgtttcaat
    14461 gctttcggtg atggtgtggc gcaactgggc cgctcgctgg atgttgatgc caataccaac
    14521 ggtcaggtgg tgatccgtga tagcgccatc aacgaaggtt ttaacacggc taaaccgtgg
    14581 gccgatgcgg tgatctctaa tcgtccgttt gcgggtaata ccggcagcgt agatgataac
    14641 gacgaaatac agcgcaatct gaatgacact aactacaacc gcatgtggga atacaataac
    14701 cgcggcgtgg gtagtaaagt ggttgcagag gcgaagaagt aagagcaatt aactatttgc
    14761 cggatgcggc gtaaacgcct tatccggcct acggttcgat gcgatttgta ggtcggataa
    14821 gatgcgcaag catcgcatcc gacaataagt gccggatgct gcgaaaatgc cttatctggc
    14881 ctacagattc gatgcgattc gtaggtcgga taagatgcgc aagcatcgca tccgacaata
    14941 agtgccgaat gcgacctaca ttcacatggc gctttttaca tctgacggtt tttattgaag
    15001 ttaatcaaac tacccgcctt gataatctcg cgctcttcag cagtcagact ttccatatag
    15061 agcgtaattt ccgttaccgg cgcatcttca tggatcacat aacctttaaa cgtcgtaccc
    15121 ggattatcca gcgccgcttt aatgccaggg atgtaaatgt aatcccccac ttcaaaggtt
    15181 ggtacttccg ccatttgcag cggtaacatc ccccagttga tgacgttaga acgatagcgt
    15241 ttagtcgcgt actcctcggc aatattcgcc agaccgccaa tcacacgctg gcagctcgcc
    15301 gcctgttcac gcgcagaacc atcgcctggt ttcaccgcat agaccatgct gccaatttca
    15361 gtttgcagcg gatcaatatg ctcctgacca gcaatctgct taatgcgcgc aaacacctct
    15421 gtcagctcgc tgacattccc cgccagacgc tgattttcca gctcagcagt cgctttactt
    15481 ctgctaacat aaccgggatc gcggcgagac agggtaaact ccgccagacc aatcggattt
    15541 gaacgataag aagaggtttc accggaagga atcagttcgt cggtggtggt cacttcgtcg
    15601 aggatcttcg agcacacttt caggacgata ttgtcagtca gcgcacccaa ttccggccag
    15661 tctttaatgt tcggcccgta aatcagcggt tgctgagttg cccctttcac aaagccctga
    15721 taaacacggt ttttatacgg cgttacatcg aaggcgtact ccggcacgtt gtcccagcaa
    15781 tcaagttcgc tggcagaggt taaatagcca ccgtttgccg cagtcgcagc gatagaacga
    15841 gcgtccatca acgccaccgc tgacatctgc ccattagctg gcttagagcc ttcgcggttc
    15901 gggaagttac gcgtggtgtg gcgaatactc aaaccgttgt tgattggcgt atcgcccgcg
    15961 ccaaagcatg ggccgcagaa cgcggttctg atgattgcgc ctgcgccaat caaatctgct
    16021 accacacctt ttttggcgag atccataaac accggctgtg atgacgggta aactgccagc
    16081 gagaaggtgt cattgccaca ggattgaccg cgcagtgcat tcgccgccgc gatgacgttt
    16141 tcgtagttac cgccagaaca gcccgcgata atcccctgct gcactttcag gcgaccattt
    16201 tccactttat ccagcagcga gagtttggct ttaccgtgcg ccacgcgttc ggactcaatt
    16261 tcaatctcac gcagaatgtc ggtcaggttc tggttcagtg tgtcgatttc atacacgttg
    16321 ctcgggtgga acggcagcgc aatcattggt ttgatggcgc ttaaatcaac gctgatgcag
    16381 ccatcgtagt acgccatcgg ttgagggtta agctggcagt aatcctggcc gcgaccgtgc
    16441 agcgccagcc agttatggac ttcttcatcg gtttgccaga cagaacttaa acaggtcgtt
    16501 tcagtggtca tcacgtcaac gctgttacgg aaatcggtag agagcgcgct aacgcccggt
    16561 ccaacgaact ccatgacttt gtttttgacg taaccgtttt tgaacaccgc gccaatgata
    16621 gccagcgcca catcctgtgg ccccacatac ggcgcaggtt ttccggtcag atgcaccgca
    16681 accacgcccg gatagtcgat atcccaggtg tcattaagca gctgttttac caactcaccg
    16741 ccgccctcac cgactgccat tgtccctaat gcaccgtaac gggtgtggct gtctgacccg
    16801 aggatcattt tgccgccgcc tgccatcatc tcacgcatat attgatggat gaccgcaata
    16861 tgcggaggca caaaaatacc gccataacgc tgggccgccg ataaaccaaa aacatggtca
    16921 tcaccgttaa tagtgccgcc gacggcgcag agtgagttat ggcagttggt cagcacatac
    16981 ggcagcggga aacgttccat accggacgct ttagcggtct gtacaatacc aacaaaggta
    17041 atatcgtgag aggctaatga atcaaactta attttaagtt tatccatatt tccggacgta
    17101 ttatgcgaag agagaataga ccaggcaata gtgccttttt tggcttcttc ttttttaatt
    17161 tcgccggtga aatgttcttc ggcaattatt tcgttattac tggcgagaaa cacgcctttt
    17221 tcagataact tgatcatcaa atgctccaga tatctgcgca ccgtgaagtg cgcagaaaga
    17281 taataaatgg atatactcta aataattcga gttgcaggaa ggcgacaagc gagtgaatcc
    17341 ccaggagctt acataagtaa gtgactgggg tgagcgaacg cagacgcagc acatgcaact
    17401 tgaagtatga cgagaatatt tacagcatgt tccagccgat cagcatattc caccaccaca
    17461 cgccgagggt gatatgcacc aggaaggtta atatcgtcag taccgcaccg accaaccacc
    17521 aggatttaat atcgttataa cccacgccaa agatgaccgg acctgccgcg ccgccatagt
    17581 gagtaaccat gccgccatag gagttggaga acaacagtgc cagcgcggtt aacattaacg
    17641 gtgcgccgga gacgttcgcc agcatggcaa ataccggtaa catagcaacg atataggcac
    17701 taccggaagc gaagaaataa cgcacgataa tgctgaggaa aataataacg aagaaagcaa
    17761 cgttaccgtg accatcaaat gccaggttat ttttaaagac ttcagctaac cattcgaaga
    17821 atttaacttt cgataataag gagcttaagc cgataatacc gccgtaccag attaaggtat
    17881 tccagccgcc tttattttta accacgtctt cccaggtaac gatacccagc agcagcatgg
    17941 ttgccataac aacgattgcc acggtggatt catcaacccc cagagactta ctgaaaatcc
    18001 agcccagcag cgccagcaca aagacaccga gcagcatttt ttcgcggatt ttcatcggtc
    18061 ctagttcggc aaggcccgct ttagcgatgg ttttgttatc caccttctta atttctggtg
    18121 gatacatggt gtaaatcacc agcggggtga ccagcagcat aatgatgccc ggcaatccgg
    18181 ctgccagcgc ccatccaccc cagctaattt gcaggtgcag aatgtcgttg atcattttca
    18241 gcgccagaat gttccccgcc attgcggtaa agaacatata gctggtggtt ttggtgacca
    18301 tgtaaatgga catcatcagg taatgtccga cacgacgcgg acttttttcc ggttcggacc
    18361 ccaaagccac cgccacgctg ttgatgatcg gtaacacaat gccgcccgca cgcgcggtgt
    18421 tagacggtgt tgccggagcc agtaccagat cgaggaatac cgtaacgtaa cccagaccca
    18481 gcgtggtgtt accgatttta ccaatcagca gataggcaat acgtttacct aaaccggtgg
    18541 tcacaaatgc ggcgcttaag gtaaacgccg agaacaccag ccaggtggta cctgaagagt
    18601 aaccgcttaa tacggcggtg gttttaaacg caccgtcgga taagttaccg accaccacca
    18661 ttgaggcagc aacggcaatt aacagtacga caggttccgg gaaaggcttg ataaccagcc
    18721 ccacaatggc cgccaggtaa ataccaaaaa gcacccacgc cagttcgctt aatcctgccg
    18781 gagctggcat aaaaccaata atacatggga tcgctaatat cagaattagc ttccataacg
    18841 atttcttatt catttaaaat cctgttcttt ctgtatgact catacagaag tcctttattg
    18901 attgtcctta tcctgacaac gaattttttc agggaagata aacttcaccg gaaaatattt
    18961 ttctggtcgt ccgaataaca gatgcgcgta acgtcgtggc atcctgacct tcattactta
    19021 aatgaacgtc gagcgcacca ctggggtgtt caatattgat attgccgtat cctacagaag
    19081 ggacgatttg tcgggtgacg gtgccttcca atgcacaact actggaaata gcaatagcac
    19141 cggttatcgc cagcgcgcga tggcaagaat gcggcataaa ataacgcaca ttaattgccc
    19201 cgcctttctg cgctggagaa ataagcacag gtttagggat aaccatatta ctgacatcac
    19261 ctaagcccat tgttttaccc gcttgtagac ggatagattc aatgcgggct aataatgctt
    19321 tgtcggcatc cagttccgcc ggtaattcat aacctgtttt tcccagatat tcagccggaa
    19381 taatgacgac tggcatcgcc atatcgatac aggtcaccgg gacatcgtca aaataatcaa
    19441 tctgattatc agtcgggaaa acttttccgg ttttggttcc agcggcattc aggaaagtga
    19501 gcgcaaccgg tgcggcagta cccggtacgc cgtcaattct ggcgctaccc tcgtactcga
    19561 caacaccatt tggcgtttgc acatcagctt cgatgaacgt acccgtattg acgttgcgga
    19621 tacgtacgcg agtaactggc gaagtcgctg caatcaaacc attttcaatg gcgaatgccc
    19681 caacaccaga cagcatattg ccgcagttag gcgtggtatc gacacgttgc tcatgaacga
    19741 ttacctgcgc aaacagataa tcgacatcag cacgcggatc gctggaacgg ctaataatgg
    19801 cgactttact ggtcagtgga ttaccgccgc caataccgtc aatttccaga tcgttaccgg
    19861 aacccataat tgccatcaat attttatcgc gctgcgtttg atcttcgggt aaatgttccg
    19921 ctaacaggaa cgcgcccctc gaggttccac ctcgcatcat cacgcagggt atttttttca
    19981 taataatgcc ctcaatttaa aaacataact tattgcgata tggttacatt aagggcaaag
    20041 catctctaat gactttagct caacgattaa taacattttt tcattaattt aagttggcta
    20101 aatgcagtta aaatttttaa cggccagcca cccaaaatcg tcgcttccat tttccggagt
    20161 aataatgaag catgaattat caagtatgaa ggcatttgtc atactggcag aatccagttc
    20221 gtttaacaat gccgctaaat tactcaatat tacgcaacct gcattaacgc gaagaataaa
    20281 aaagatggag gaagatttac atattcaact atttgagcgt acaactcgca aggttacgtt
    20341 aacaaaagca ggaaaaaggt tgctcccgga ggcgcgggaa ttaataaaga aattcgatga
    20401 aacgcttttt aatattcgtg atatgaatgc ttatcatcgt ggtatggtga cgttagcgtg
    20461 tattccgacc gcagtatttt attttttacc gctggcaatc ggtaaattta atgagctgta
    20521 tcccaatatt aaagtgcgga ttctggaaca aggcacgaat aattgcatgg aatcggtgct
    20581 gtgtaacgaa tcagactttg gcataaacat gaacaacgtc acaaattcat ccattgattt
    20641 taccccactg gtcaacgagc cgttcgtgct ggcctgtcgg cgtgaccatc cattggccaa
    20701 aaagcagctt gtagaatggc aggagttagt gggttacaaa atgattggcg tacctcctcc
    20761 agcggcaacc gactgttgat agaacaacag ctggccgaca agccctggaa gctggactgg
    20821 ttttacgaag tgcgtcatct ttcgacgtca ttaggactgg tggaggcggg actggggatt
    20881 tcggcgcttc ctggcctggc aatgcctcat gcgccctatt cttcgattat tggtatccca
    20941 ttggtggaac ccgttatacg tcgaacattg ggaataattc gccgtaaaga tgccgtactt
    21001 tctccagcag cagaacgctt ttttgccttg ctgattaatt tatggactga cgataaagac
    21061 aatttgtgga ccaatatcgt cgaacgccag agacacgcgt tacaggagat aggttaatac
    21121 accggcgcag gagagactgc gccgggtaaa tcagcggtta gtgtgcgtta accaccaccc
    21181 acattggtcc ctgcccgacc gcatagcggc ctttttcatg cagtagcccc tgctcgccaa
    21241 caatttcgta taccgagatg tggtgagatt tttgcccggc ggcaatcaga tacttgccgc
    21301 tgtgatcaac attgaagccg cgcggctggg tttccgttgg ctggaagcct tctttactca
    21361 acacgctgcc atcttccgaa acgctgaaaa cggtaatcag gctggcggta cggtcgcagg
    21421 cgtataaatg gcgaccatcc ggggtgatat gaatatcagc cgcccaacgg gtgtcggaga
    21481 agttttccgg catcatatcc agcgtctgga cacattcgat attaccgtgc ggatctttca
    21541 gttcccagac atccactgag ctgtttaact cattgacgca atacgcatat tgttcgtttg
    21601 gatggaatac catatgacgc gggccggccc cttcaacggt ggtcacttcc gcagggtcct
    21661 gcgccacgag atgaccatca tcgctgaccg taaacaggca aatgcgatcc tgctttaatg
    21721 ccggaaccca cagcgtacgg ttgtccggtg agatattggc ggaatggcaa ccgtccagcc
    21781 cctcgaccac atcgacgacg cccactggca ggccatcttc cagacgcgtt acgctcacgt
    21841 tacccgcatt gtaagaacct acaaagacaa actgcccctg gtgatcggtg gaaatatgcg
    21901 tcggactacc cggcagcgca gactctgcgg caaaggtcag tgcgccatcg tccggggcga
    21961 tacgatacgc caggacgcga aactcagggc gaacaccaac atagagataa cgtttgtccg
    22021 ggctgaccac catcggctgc acctgccccg gcacatcgac aacctgtgtc agcgtcagtg
    22081 cgccttcatg attcagattc cagacgtgaa tttgctggct ctcagggctg gcgatataaa
    22141 ctgtttgctt catgaatgct cctttgcatt tagcaactga ctgtaacagc taaaattagt
    22201 cgcttttggc ggtgaatgct gaattaaaac gcagaatttt gtccgatagt ggtatcggtg
    22261 taccattcgc gcagacgaaa attcttaacc ttaatctgga atacgccatg accacacgcg
    22321 tgattgctct cgacttagac ggcaccttat tgaccccgaa aaagaccctg cttccttcat
    22381 cgatagaagc cctggcccgc gctcgcgaag caggctatca attaatcatc gtcacaggtc
    22441 gccatcacgt cgctattcat cctttttatc aggcgctggc gctggataca cctgctattt
    22501 gctgtaatgg cacctatttg tatgattatc atgcaaaaac cgtgctggaa gcggacccaa
    22561 tgcccgttat taaagccctg caactcattg agatgctgaa tgaacaccac attcacggtc
    22621 tgatgtatgt cgatgatgca atggtctatg agcacccgac cgggcatgtc attcgcacat
    22681 ctaactgggc gcaaaccctg ccgccggaac agcgtccgac tttcacacaa gtcgcttctc
    22741 tggctgaaac ggcgcaacaa gttaacgccg tatggaagtt cgccctgacg cacgatgacc
    22801 tgccgcaatt gcagcatttt ggtaagcatg tcgaacatga actgggactg gagtgtgaat
    22861 ggtcctggca cgatcaggtt gatattgcac gcggcggcaa cagcaaaggt aaacgtttga
    22921 cgaaatgggt tgaggcgcaa ggttggtcga tggaaaacgt cgtggcattc ggcgataact
    22981 ttaatgatat cagtatgctg gaagccgctg gtacaggcgt ggcgatgggc aacgccgatg
    23041 acgcggtaaa agcgcgcgcc aacattgtga ttggtgataa caccaccgac agcattgccc
    23101 agttcattta tagccacctg atttaatcag gcggttatcg acacactttt aatttgcgcg
    23161 tacagccaca ggccaggttt gatcgccagt tcatccctgg cccacgggct gatacgcgcc
    23221 cacagcgttt taccgccgac ttccagttcc acttccacct ggccgttgtc gtcataacta
    23281 ttaacaactt ttgcccgcaa tacgttacga atgctggttt gctgcggcgg ttgtaaaacc
    23341 agagaaacat cggaagcctg aatgcggata cgtagcgcag cttgcagcgg ttcgtccagc
    23401 ttattgaccc acaaatgctg atcgcccagc gccagcgcgg tcatcgcgta atgcggatga
    23461 tgctcaagca ccgtcacttt cagaatgcta ctttgttgct ctttcggcag ccacggattc
    23521 atcacgctac tgccccacac ttcctccagc gcgccaaagg ctttcacctg accgttttcc
    23581 agtaccatca ctctgtctgc cagatggagg atctcatcca gcgaatggct gacatacaac
    23641 atcggaatgt tgatttcccg tgtcagccgt tgcagataag gcaacagttc gcgtttacgc
    23701 ggaatatcca gtgacgccag cggttcatcc agcaacagca attccggtgc tgtcagcaaa
    23761 gcccgaccaa tcgccacgcg ctgtttttcg cctccggaca ggctgcctgg taaacggtca
    23821 agcaacggtt caatgcctaa aagcgccacc agcttatcga actgatcgac catacttttc
    23881 gacatgccgt agcgcagatt gccacgcact ttgtaatgcg ggaacagccg cgcatcctga
    23941 aaaacatagc caacgcgacg cttttccggc gtcaggcaga tacctttttc ggcatcattt
    24001 agtacccgcc cattgaggac aatccgccct ttttgcgggc gcgtcagtcc actgatggcg
    24061 ttaatcagcg aagtttttcc ggcaccggag acgccaaaga tagcagtgat gccattggcg
    24121 ggcagcgttt cattaatagt caggcaatgg ttgcccaacg tctgggaaaa attcagttcc
    24181 agcatgatta gcgccccgcc cgttcacggc tgattctggc cagccattct gaaatcaaca
    24241 gggagatcat cgccagcgca atagaaataa tgcacagtct cgccgctcca ctttccccgc
    24301 cgggggtctg gatcagggta tacatggcag aaggaatggt tcgcgtttca ccaggaatgt
    24361 tcgacacaaa ggtgatggtt gcaccaaact caccgagaga acgagcaaaa gccagtaccg
    24421 taccaacaat aattcccggt aaggtcagcg gtaacgtgat agtaaagaaa acgcgccagc
    24481 gcccggcccc cagtgttctt gcggcctgtt ccagtttgac atcaacccct tccagcgcca
    24541 gacgaattgc ccgcaccatc agcggaaacg acatgacggc ggcagcgaga accgcgccgc
    24601 gccagctaaa ggcgaaggta ataccaaacc agtcatacag acgttcaccg ataaatccgc
    24661 gccgtcccat cgaaactaat aataagtaac cgacgaccac gggcggtaac accagcggta
    24721 gatgcagtac gctgtcgagc agagctttgc ccggaaacgt gcaacgcacc agtaaccagg
    24781 caaaaaagat cccaaacggc aggctaaaca gcacagccag ggaagaaact ttcaggctta
    24841 ataaaactgc ctgccattct ggatcggtca gtatcattac ttgattgtaa atccgtaacg
    24901 tttaaagatt tccgctgcct gcggtccctt cagataatca taaaatgctt tcactgtcgc
    24961 attgttatgc ccttccacaa cagcaaccgg atattccact tttttatgtg aatcttccgg
    25021 gaaggtggca accactttta cccctttgct ggcaactgcg tcagaaccgt agacaatgcc
    25081 cagaggcgct tcgttacgtt cgaccagcgc cagcgcccca cgaacatctt ccgctggggc
    25141 cagtttcgga gagagcgtat cccatgcgcc cagtttttgc agtgcttctt ttgcataaat
    25201 gccagcggga acatgttccg gatcgccaac cgccaggcga ccgccattca gcagtgaagt
    25261 ccagttggtt ttgctgtcga tggtgaaatc tttctgcacg ctggctttcg gtgctacaac
    25321 gaccaggcta ttgccgagca gtgtctgacg cgtagctgta tcgatcgctt ttttatcaac
    25381 cgcataatcc atccatttct gatcggcaga aataaacaga tccgcaggcg cacccgcttc
    25441 aatctgacgg gcgagagtag atgacgaagc gaaagaagaa accacatcca cgcctttctc
    25501 ttttttaaac tgcgtagcaa tgtcctgcat tgcgttagtc agtgatgcgg cggcgaacac
    25561 cgtgattttc ccttcatctg ccagtgcatt gccagcaaca gcgaaagaga gtgccgcccc
    25621 ggcaaacaag ttcaaccatt tacgagccat tggtaacccc ttaatgtaac gttatgtagg
    25681 cgacaatata acgactaact cggaattttc ccagcagtta ttgctaacct ttgtgaggta
    25741 gataagaaaa aatatcggca ggaaaagcag gaagttgaga aaaagaaaat gcccgactaa
    25801 gcgggcattc agggaatcaa tgattttgtc cgggctggtc ttttttacca acaccagaaa
    25861 agatgttgaa tacttcacca agaccgtaaa tcagacccag gatgatggcc atcacgacag
    25921 gtaccatgat tacggcgaat accagacttt ttaataactc taacatggtc aactccagat
    25981 atagtcatga gactattcta accgctaagc acagaaaagc actccccttt tgtgcggtca
    26041 gctttgcgtg gcgttcgttt tccgtcacaa taagactttt gccaggacat tgttatgcag
    26101 gccgaaatcc ttctcaccct taagctccaa caaaaattat tcgccgaccc gcgccgcatt
    26161 tcgctactaa aacacattgc gctttccggt tccattagcc agggagcgaa agatgccggt
    26221 attagctata aaagcgcctg ggatgccatt aacgagatga atcagttaag tgagcatatt
    26281 ctggtcgagc gcgcaacagg cggtaaaggt ggcggcggcg cagtactgac ccgctatggt
    26341 cagcgactga ttcagctcta tgacttactg gcgcaaatcc agcaaaaagc ctttgatgtg
    26401 ttaagtgacg atgacgccct gccgctgaac agcctgctgg ccgcgatctc acgtttttca
    26461 ctgcaaacca gcgcccgtaa ccagtggttc ggtaccatca ccgcccgcga tcatgatgac
    26521 gttcaacagc atgttgatgt cttactggct gacggaaaaa cacgcctgaa agtcgcaatt
    26581 accgcacaaa gcggcgcgcg tctggggctg gatgaaggca aagaagtgtt gatattgcta
    26641 aaagcgccgt gggtaggtat tactcaggac gaggcggtcg cgcaaaacgc tgacaaccaa
    26701 ttaccgggta ttattagtca tattgagcgc ggcgcagagc agtgcgaagt attaatggcg
    26761 ctacccgacg ggcaaacact gtgcgccaca gtgccggtaa atgaagcgac ttctcttcag
    26821 caaggacaga atgtcacggc ctactttaat gccgacagcg tgattatcgc cacgctgtgc
    26881 taagcgtgtt gacaatttgt tatgaaacac gtatccctgt cagtaatcgc tgcacaaagt
    26941 gggatataaa atgtcatcgt tgcaaatttt gcaaggcacg tttcgtctta gcgacacaaa
    27001 aacgctgcaa ttgcctcagc taacgttaaa cgcgggtgat agttgggcgt ttgtcggttc
    27061 gaatggaagc gggaaatcgg ccctggcccg cgcgctggcg ggggaacttc cgcttttgaa
    27121 aggtgaacgg caaagccagt tttcccacat cactcgtctc tccttcgagc aattgcaaaa
    27181 actcgtcagc gacgaatggc agcggaataa caccgatatg ctcggccctg gcgaagatga
    27241 caccggacgc actacggctg agatcattca ggatgaagta aaggatgcac cgcgttgcat
    27301 gcaactggcg cagcagttcg gtattaccgc cctcctcgac cgacgcttta aatacctttc
    27361 cactggcgag acgcgaaaaa ccctgctgtg tcaggcgctg atgtcggagc ctgacttgtt
    27421 gattcttgat gagccgttcg atggcctgga tgttgcctca cgtcagcagc tggctgagcg
    27481 actcgcctcg ttacatcagt ccggtattac tctggtactg gtgctcaatc gcttcgatga
    27541 gatcccggag tttgtccagt ttgctggcgt gctggcggat tgcacgttag cggaaactgg
    27601 cgctaaagag gaactgctcc aacaagcact cgtcgcgcaa ctggcgcata gtgaacagct
    27661 tgaaggtgtg caactgccgg agccggatga accttcagca cgtcacgcct tacccgccaa
    27721 cgaaccgcgc attgtgctga acaatggcgt ggtttcttat aacgatcgcc ccattcttaa
    27781 taaccttagc tggcaggtga atccaggcga acactggcaa attgtcgggc caaatggtgc
    27841 aggaaaatcg acgttattaa gcctggttac tggcgatcat ccgcaaggtt acagcaacga
    27901 tttgacgctt ttcggacgac gtcgcggcag cggcgaaacc atctgggata tcaaaaagca
    27961 tatcggttac gtcagcagta gtttgcatct ggattaccgg gtcagcacta ccgtgcgtaa
    28021 tgtgattctt tctggctatt ttgattcgat tggcatttat caggccgttt cggatcgcca
    28081 gcaaaaactg gtgcagcagt ggctggatat tctcggcatt gataaacgca cggctgacgc
    28141 tccgttccat agtctttcct ggggacagca gcgtctggcg ctgattgtcc gcgcactggt
    28201 gaaacatccg acgttgctta ttctcgatga accactacag gggcttgatc cgctgaatcg
    28261 ccagcttatc cgccgttttg ttgatgtgct gattagcgaa ggtgaaacgc aattgttgtt
    28321 tgtttcgcac cacgctgaag atgcgcctgc ctgtattacc catcgtcttg agttcgtgcc
    28381 ggacggtgga ctctatcgct atgtgctgac aaaaatatat tgagtcggta gtgctgacct
    28441 tgccggaggc ggccttagcg ccctctccgg ccaacggttc gacgcatgca ggcatgaaac
    28501 cgcgtctttt ttcagataaa aagcgcaatc attcataaac cctctgtttt ataatcactt
    28561 aatcgcgcat aaaaaacggc taaattcttg tgtaaacgat tccactaatt tattccatgt
    28621 cacacttttc gcatctttgt tatgctatgg ttatttcata ccataagcct aatggagcga
    28681 attatgagag ttctggttac cggtggtagc ggttacattg gaagtcatac ctgtgtgcaa
    28741 ttactgcaaa acggtcatga tgtcatcatt cttgataacc tctgtaacag taagcgcagc
    28801 gtactgcctg ttatcgagcg tttaggcggc aaacatccaa cgtttgttga aggcgatatt
    28861 cgtaacgaag cgttgatgac cgagatcctg cacgatcacg ctatcgacac cgtgatccac
    28921 ttcgccgggc tgaaagccgt gggcgaatcg gtacaaaaac cgctggaata ttacgacaac
    28981 aatgtcaacg gcactctgcg cctgattagc gccatgcgcg ccgctaacgt caaaaacttt
    29041 atttttagct cctccgccac cgtttatggc gatcagccca aaattccata cgttgaaagc
    29101 ttcccgaccg gcacaccgca aagcccttac ggcaaaagca agctgatggt ggaacagatc
    29161 ctcaccgatc tgcaaaaagc ccagccggac tggagcattg ccctgctgcg ctacttcaac
    29221 ccggttggcg cgcatccgtc gggcgatatg ggcgaagatc cgcaaggcat tccgaataac
    29281 ctgatgccat acatcgccca ggttgctgta ggccgtcgcg actcgctggc gatttttggt
    29341 aacgattatc cgaccgaaga tggtactggc gtacgcgatt acatccacgt aatggatctg
    29401 gcggacggtc acgtcgtggc gatggaaaaa ctggcgaaca agccaggcgt acacatctac
    29461 aacctcggcg ctggcgtagg caacagcgtg ctggacgtgg ttaatgcctt cagcaaagcc
    29521 tgcggcaaac cggttaatta tcattttgca ccgcgtcgcg agggcgacct tccggcctac
    29581 tgggcggacg ccagcaaagc cgaccgtgaa ctgaactggc gcgtaacgcg cacactcgat
    29641 gaaatggcgc aggacacctg gcactggcag tcacgccatc cacagggata tcccgattaa
    29701 ggaacgacca tgacgcaatt taatcccgtt gatcatccac atcgccgcta caacccgctc
    29761 accgggcaat ggattctggt ttcaccgcac cgcgctaagc gcccctggca gggggcgcag
    29821 gaaacgccag ccaaacaggt gttacctgcg cacgatccag attgcttcct ctgcgcaggt
    29881 aatgtgcggg tgacaggcga taaaaacccc gattacaccg ggacttacgt tttcactaat
    29941 gactttgcgg ctttgatgtc tgacacgcca gatgcgccag aaagtcacga tccgctgatg
    30001 cgttgccaga gcgcgcgcgg caccagccgg gtgatctgct tttcaccgga tcacagtaaa
    30061 acgctgccag agctcagcgt tgcagcattg acggaaatcg tcaaaacctg gcaggagcaa
    30121 accgcagaac tggggaaaac gtacccatgg gtgcaggttt ttgaaaacaa aggcgcggcg
    30181 atgggctgct ctaacccgca tccgcacggt cagatttggg caaatagctt cctgcctaac
    30241 gaagctgagc gcgaagaccg cctgcaaaaa gaatattttg ccgaacagaa atcaccaatg
    30301 ctggtggatt atgttcagcg cgagctggca gacggtagcc gtaccgttgt cgaaaccgaa
    30361 cactggttag ccgtcgtgcc ttactgggct gcctggccgt tcgaaacgct actgctgccc
    30421 aaagcccacg ttttacggat caccgatttg accgacgccc agcgcagcga tctggcgctg
    30481 gcgttgaaaa agctgaccag tcgttatgac aacctcttcc agtgctcctt cccctactct
    30541 atgggctggc acggcgcgcc atttaatggc gaagagaatc aacactggca gctgcacgcg
    30601 cacttttatc cgcctctgct gcgctccgcc accgtacgta aatttatggt tggttatgaa
    30661 atgctggcag agacccagcg agacctgacc gcagaacagg cagcagagcg tttgcgcgca
    30721 gtcagcgata tccattttcg cgaatccgga gtgtaagaaa tgagtctgaa agaaaaaaca
    30781 caatctctgt ttgccaacgc atttggctac cctgccactc acaccattca ggcgcctggc
    30841 cgcgtgaatt tgattggtga acacaccgac tacaacgacg gtttcgttct gccctgcgcg
    30901 attgattatc aaaccgtgat cagttgtgca ccacgcgatg accgtaaagt tcgcgtgatg
    30961 gcagccgatt atgaaaatca gctcgacgag ttttccctcg atgcgcccat tgtcgcacat
    31021 gaaaactatc aatgggctaa ctacgttcgt ggcgtggtga aacatctgca actgcgtaac
    31081 aacagcttcg gcggcgtgga catggtgatc agcggcaatg tgccgcaggg tgccgggtta
    31141 agttcttccg cttcactgga agtcgcggtc ggaaccgtat tgcagcagct ttatcatctg
    31201 ccgctggacg gcgcacaaat cgcgcttaac ggtcaggaag cagaaaacca gtttgtaggc
    31261 tgtaactgcg ggatcatgga tcagctaatt tccgcgctcg gcaagaaaga tcatgccttg
    31321 ctgatcgatt gccgctcact ggggaccaaa gcagtttcca tgcccaaagg tgtggctgtc
    31381 gtcatcatca acagtaactt caaacgtacc ctggttggca gcgaatacaa cacccgtcgt
    31441 gaacagtgcg aaaccggtgc gcgtttcttc cagcagccag ccctgcgtga tgtcaccatt
    31501 gaagagttca acgctgttgc gtatgaactg gacccgatcg tggcaaaacg cgtgcgtcat
    31561 atactgactg aaaacgcccg caccgttgaa gctgccagcg cgctggagca aggcgacctg
    31621 aaacgtatgg gcgagttgat ggcggagtct catgcctcta tgcgcgatga tttcgaaatc
    31681 accgtgccgc aaattgacac tctggtagaa atcgtcaaag ctgtgattgg cgacaaaggt
    31741 ggcgtacgca tgaccggcgg cggatttggc ggctgtatcg tcgcgctgat cccggaagag
    31801 ctggtgcctg ccgtacagca agctgtcgct gaacaatatg aagcaaaaac aggtattaaa
    31861 gagacttttt acgtttgtaa accatcacaa ggagcaggac agtgctgaac gaaactcccg
    31921 cactggcacc cgatggtcag ccgtaccgac tgttaacttt gcgtaacaac gcagggatgg
    31981 tagtcacgct gatggactgg ggtgcgactt tactttccgc ccgtattccg ctttccgatg
    32041 gcagcgtccg cgaggcgctg ctcggctgtg ccagcccgga atgctatcag gatcaggccg
    32101 cgtttctggg ggcctctatt ggtcgttatg ccaaccgtat cgccaatagc cgttatacct
    32161 ttgacggtga aaccgtgacg ctttcgccaa gtcagggcgt taaccagctg cacggcgggc
    32221 cggaagggtt cgacaaacgt cgctggcaga ttgtgaacca gaacgatcgt caggtgctgt
    32281 ttgccctgag ttcagatgat ggtgatcagg gcttcccggg taatctcggc gcgacggtgc
    32341 aatatcgtct gaccgacgat aaccgtatct ccattactta tcgcgccaca gttgataaac
    32401 cttgcccggt gaatatgact aatcacgtct atttcaatct tgacggcgag cagtctgacg
    32461 tgcgcaatca caagttgcag attctggcgg acgaatatct gccggttgat gaaggcggca
    32521 ttccgcacga cggcctgaaa tctgtcgccg gaacgtcttt tgatttccgc agcgccaaaa
    32581 tcatcgccag tgagtttctt gccgacgacg atcagcgcaa agtgaaaggt tacgatcacg
    32641 cattcttgtt acaggccaaa ggcgatggca agaaagtggc ggcgcatgtc tggtcagcag
    32701 atgaaaaatt gcagctgaag gtctacacca ccgctccggc tctgcaattc tactccggca
    32761 acttcctcgg cggcacaccg tcgcggggaa ccgaacctta cgccgactgg caagggctgg
    32821 ctctggaaag cgagtttcta ccggacagcc cgaaccaccc tgaatggccg caaccggact
    32881 gcttcctgcg tcctggcgaa gagtattcca gcctgacgga atatcagttt attgctgagt
    32941 aatgttacgc cctcgtcatg agggctttat ctcatattgt tcaaatcacc agcaaacacc
    33001 gacatatttg caactcaata ttcacaacaa ccttacactg cgccactatt ttcgctatgg
    33061 ttatgcgtaa gcattgctgt tgcttcgtcg cggcaatata atgagaatta ttatcattaa
    33121 aagatgattt gaggagtaag tatatggctg taactaagct ggttctggtt cgtcatggcg
    33181 aaagtcagtg gaacaaagaa aaccgtttca ccggttggta cgacgtggat ctgtctgaga
    33241 aaggcgtaag cgaagcaaaa gcagcaggta agctgctgaa agaggaaggt tacagctttg
    33301 actttgctta cacttctgtg ctgaaacgcg ctatccatac cctgtggaat gtgctggacg
    33361 aactggatca ggcatggctg cccgttgaga aatcctggaa actgaacgaa cgtcactacg
    33421 gtgcgttgca gggtctgaac aaagcggaaa ctgctgaaaa gtatggcgac gagcaggtga
    33481 aacagtggcg tcgtggtttt gcagtgactc cgccggaact gactaaagat gatgagcgtt
    33541 atccgggtca cgatccgcgt tacgcgaaac tgagcgagaa agaactgccg ctgacggaaa
    33601 gcctggcgct gaccattgac cgcgtgatcc cttactggaa tgaaactatt ctgccgcgta
    33661 tgaagagcgg tgagcgcgtg atcatcgctg cacacggtaa ctctttacgt gcgctggtga
    33721 aatatcttga taacatgagc gaagaagaga ttcttgagct taatatcccg actggcgtgc
    33781 cgctggtgta tgagttcgac gagaatttca aaccgctgaa acgctattat ctgggtaatg
    33841 ctgacgagat cgcagcgaaa gcagcggcgg ttgcaaacca gggtaaagcg aagtaaacgt
    33901 cattcgttta aaatgagaaa gccgactgca agtgagtcgg cttttttgtt gctaacaatg
    33961 gagcacattg cctgatgcga cgctgcgcga cttatcaggc ctgtggtgat tcatcggata
    34021 cgccactctg acggcgcatc cgacaattaa accttacccg caacgcgctt ttactgcatt
    34081 cgccagttga cgtaacagag catcggtatc ttcccagccg atgcaggcat cggtgatgct
    34141 cttaccgtag gccagcggct ccccgctctc gaggctctga ttgccttcca ccagatggct
    34201 ttccaccatc acgccaataa tggccttttc gccaccggca atctgctggc aaacgtcagc
    34261 acaaacatcc atctgctttt tgaattgttt ggacgagtta gcatggctga aatcgatcat
    34321 cacctgtgct ggcaggcctg ctttattcag cccttctttc acttcagcaa cgtgcttcgc
    34381 gctgtagtta ggctctttac cgccgcgcag aatgatatgg caatcgccgt taccgctggt
    34441 attcacaatc gccgaatgcc cccatttcgt tacggacagg aagcagtgcg gcgcaccggc
    34501 ggcattaatg gcatcgatag ccactttaat cgtaccgtcg gtgccatttt tgaagccgac
    34561 cggacaagaa agccctgatg ccagttcgcg gtgcacctgc gattcggtgg tacgtgcgcc
    34621 aattgcgccc cagctcatca ggtcagcgag atattgtggg gtgatcatat cgagaaactc
    34681 acctgccgct ggcagaccgc tgtcgttaat atcaagcagc aatttacggg ctatacgcag
    34741 accgtcgttg atctggaagc tattatccat atgcggatcg ttaatcagcc ctttccagcc
    34801 caccgtggta cgcggctttt caaaatagac gcgcattacg atttccagct catctttcag
    34861 ctcttcacgc agcgccagca agcgagtggc atactctttt gccgcgacag gatcatgaat
    34921 tgagcatggg ccaatcacaa ccaacaggcg atcatcatta cctttcagga tcttatggat
    34981 cgcttttcgg gcatgggcaa ccgtattcgc ggcattttca gtagcgggga atttttccag
    35041 caatgcgaca ggaggaagta actctttgat ttctttgatg cgtaaatcgt cgttctgata
    35101 attcatgtct gttccagtgt tgccatactt atcttagtga atgcaatact tccaatctat
    35161 atcttccgtc agaatgtgta aacggggttt tacactatga acggattaat cctggaatta
    35221 gcaagaaaaa cgccagattg tcgcgaaaaa cgagatctct cctacaattt ctaactgtaa
    35281 ctcctttgtt tgttaattat ttcaagattc tctgctgcgt ttcataacct ggctgaaatc
    35341 ttaaaccaat gccttatatt cacctgcaaa tgcactgttg gaagaggtta tccgacataa
    35401 cgaccataac aggagcatcc tatgaaaatg acaaaactgg ccacattatt tctgactgcc
    35461 actctaagcc ttgccagcgg tgccgcactg gctgccgata gcggagcgca aactaataac
    35521 ggccaggcaa acgccgcagc tgatgcgggc caggtagccc ctgacgcccg tgaaaatgtc
    35581 gcgccaaata acgtcgacaa taacggggta aataccggtt ctggcggcac aatgctgcat
    35641 tcggatggtt cttcaatgaa caatgacgga atgaccaaag atgaagagca caagaacacc
    35701 atgtgcaaag atggtcgctg tccggatatc aataaaaagg tacaaaccgg tgatggcatc
    35761 aataatgatg tcgataccaa aaccgacggt accacgcagt aaccctgcaa aatagccaat
    35821 aatgggagag cggagtctct cccttttaat ttttcacttc taaaagcagt atgatgtcat
    35881 aaagttaagt gagaataatt aagggatgac tcgtcatggc gcactcacac tcacacacgt
    35941 cctcacacct gccagaagat aataatgctc gtcgcttgtt gtatgctttc ggcgtgactg
    36001 ccgggtttat gctggtagaa gtcgttggtg gttttctttc tggttctctg gcattgctgg
    36061 ccgatgcggg tcatatgttg accgatactg ccgccctgct tttcgcccta ctcgccgtgc
    36121 aattttcacg tcgtcctccc accattcgcc acactttcgg ttggctaaga ctgaccacgc
    36181 tcgcggcgtt tgtgaatgcc atagccctcg tggtaattac cattttgatt gtctgggagg
    36241 cgatagaacg cttccgcacg ccgcgtccgg tcgagggcgg catgatgatg gcaattgccg
    36301 tggctgggtt gctggcaaat atactttctt tctggttact tcatcacggc agcgaagaga
    36361 aaaacctcaa cgtacgagca gcggcactgc atgtgctcgg ggacctgctg ggttcggttg
    36421 gggctattat tgccgcgttg attattatct ggactggctg gacacctgct gaccccattc
    36481 tctcgatact ggtgtcgctt ctggttctgc gtagcgcgtg gcgactgttg aaagatagcg
    36541 tgaatgaatt acttgaaggt gcaccggtat cgctggatat cgctgaactg aagcgtcgta
    36601 tgtgccggga aatcccggaa gtccgcaatg tgcaccatgt acatgtatgg atggtaggcg
    36661 agaagccggt gatgacgttg catgtgcagg tgatcccgcc acacgatcac gatgccttgt
    36721 tggatcagat ccaacactac ctgatggatc actatcagat tgagcacgcc accattcaga
    36781 tggaatatca accttgtcat gggccagact gccacctgaa tgaaggggtg tctggccatt
    36841 cacatcatca ccattaatgg gacagcgcgc gtgagcctct ttcacgtgcg ctgttgatcc
    36901 acatccggct gccgttgagc gcaataaagg tcaggatgat gtactccaga gacatggcgt
    36961 aaacgccctg aagtgcaaaa ataacgacgc taatcacgtt aataatcacc cacaacagcc
    37021 agttttccac atacttacgc gtcatcagaa tcattgccac gatagataac accatcatgc
    37081 atgaatccca gaacgggaaa gcgtccggtt gcagttcagg catcacaacc tgtaatccta
    37141 atgcttgcat gatcatgact gccacgcggg tcaaaaatgc aaacaccgga ttgataaata
    37201 ccgtcatcag accaatcgaa acaacgcaaa ccgccaacca gctgagtgcc ttcggcaatg
    37261 gcaaccagcg aattttcaac tccgcctcgt tctgactggt ttgtcgcgac cacgcatacc
    37321 aaccgtaaat attcgcggca aagaaaaaca cctgtaatag caggctggca tacagctgaa
    37381 tctgaaagaa aataatgcca aacaaggtga cgttgatcag gccaaagaag tagttgctga
    37441 tcttctccag actggcaagg ccaatacaca gcaacccggc gatcgtgcct accgcttcga
    37501 tccatgagag atcataaccg cctgccccta ttggtatatg taccaggata ttctgcacac
    37561 taaaaaaatc catctttccc ccaaagcgta acgttacgcc ttattattcg ttatccacgt
    37621 agtgtagccg caaaatccag catacgattg agcggcacca gcgccctctc tcgcagcctt
    37681 tcatcaacat gaacctcgtg attgcttcct tcctgttcta atgcctctgc gatggcctga
    37741 aggccattca tggccatcca cggacaatgc gcgcagctgc ggcaggttgc accctcacct
    37801 gcggttggtg cttccagtaa ctctttatct ggcaccgcct gctgcatttt gtagaaaata
    37861 ccccgatcgg ttgccacaat aagcctctga tgtggcaatg ttttcgcagc agcgatcagt
    37921 tgactggtgg aaccgaccgc atccgccata tcgacaatag cttgtggtga ttctggatgc
    37981 accagtatgg cagcatccgg gtattcttct tgcaagcggg ttaacgcctg agtcttaaat
    38041 tcatcatgca caatacaggc accctgccag catagaatgt ctccacccgt ctgtttttgc
    38101 acgtaacgcc ccagatgttt gtcgggtgcc cagatgattt tttcacccaa actatcaaga
    38161 tgatcaataa gttcgacggc aatgcttgaa gttaccaccc aatctgcgcg cgcttttacc
    38221 gcagcagaag tgttggcgta gacgacgaca gtacgatcgg gatgggcatc gcaaaatgcg
    38281 ttaaattctt caacagggca gccgagatcc agtgaacatt cagcctgaag tgtcggcatc
    38341 agaattgttt tttccggact gagaattttg gcggtttctc ccataaatct caccccagcg
    38401 actaacaaag tagaagcggg atgctttgca ccgaagcgcg ccatttccag agaatcagaa
    38461 atacagccac cggtttcttc tgccagttgt tgaatttcgg gatcggtata gtagtgggca
    38521 accatcaccg cattacgttc ttttagcaga cgttttatct tctcgcggta atacgctttt
    38581 tcatcaatgc ttaacggcgt cggcttcggg gggaaaggat aaatcgccgt gtctggatca
    38641 aacattacgc tcatcttacc atctcgtttt acaggcttaa cgttaaaacc gacattagcg
    38701 taatattcgc tgttatcggt gtaatttgtt ttatatgcta aacaagatag tcgaatggtg
    38761 gggaaaagtc actcgaatta cgtatgagat gccgaatgcc acactttgcg tcttattcct
    38821 ccgacgtaaa gttgtttacg cagcaagcgc ggagtatgtc atcagggtca agaattgaaa
    38881 ttgagagatg cctgaatagc aaaaaagcgc ctttagggcg cttttttaca ttggtgggtc
    38941 gtgcaggatt cgaacctgcg accaattgat taaaagtcaa ctgctctacc aactgagcta
    39001 acgacccctt gcgggattat gctgctttaa tcattcagga tggtgggtcg tgcaggatga
    39061 ctggacttcg tctcgccctt cgggccgttg ctaacgcaac gttatccttc acgttctcta
    39121 ccagtaacca cctttaaatt ggtgggtcgt gcaggattcg aacctgcgac caattgatta
    39181 aaagtcaact gctctaccaa ctgagctaac gacccatatg ggtgttacct gaaagatttc
    39241 tactcggaac caatctttaa aattggtggc tcgtgcagga tgactcgctt cgctcgccct
    39301 acgggccgtt gctggcgtaa cgttatcctt cacgcttaac atctgagttt gatgttaaaa
    39361 ctggtgggtc gtgcaggatt cgaacctgcg accaattgat taaaagtcaa ctgctctacc
    39421 aactgagcta acgacccgag tggtgggtga tgacgggatc gaaccgccga ccccctcctt
    39481 gtaagggagg tgc
//
LOCUS       DAPHKZ010000032        39216 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.032, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000032 DAPHKZ010000000
VERSION     DAPHKZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39216
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.032"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            192..1847
                     /gene="aslA"
                     /locus_tag="RH288_001748"
     CDS             192..1847
                     /gene="aslA"
                     /locus_tag="RH288_001748"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase AslA"
                     /protein_id="HDV4030809.1"
                     /translation="MEISFSPKRLVVAVAAALPLMASAADTPSTATARKGFAGYDHPN
                     QYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVIFLLDDVGWMDVG
                     FNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMY
                     GQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYT
                     EWRDVHVNPEVALSPDRSEYIKQLPFSKDDVHAVRGGEQQAIADITPKYMEDLDQRWM
                     EYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDVFA
                     NLYKTLEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWK
                     GMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQS
                     NRKAEHYFLNGKLAAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLY
                     TDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD"
     gene            complement(2015..3250)
                     /locus_tag="RH288_001749"
     CDS             complement(2015..3250)
                     /locus_tag="RH288_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HDV4030810.1"
                     /translation="MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTH
                     MDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLGLEFYRRAVALQAKYGAGRKISN
                     SFQTNGVLLDDEWCAFLAEHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTFL
                     QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAAREGLKLH
                     APGDIQGELTEWSVRPDEFGEFLVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVC
                     HHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMIDSPQQQVFGEDKFKQ
                     LPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMSDLL
                     AHGRPASDIMHAHLLVVSK"
     gene            complement(3397..3473)
                     /locus_tag="RH288_001750"
     tRNA            complement(3397..3473)
                     /locus_tag="RH288_001750"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3437..3439),aa:Pro,seq:tgg)
     gene            complement(3516..3602)
                     /locus_tag="RH288_001751"
     tRNA            complement(3516..3602)
                     /locus_tag="RH288_001751"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3566..3568),aa:Leu,seq:cag)
     gene            complement(3623..3698)
                     /locus_tag="RH288_001752"
     tRNA            complement(3623..3698)
                     /locus_tag="RH288_001752"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3663..3665),aa:His,seq:gtg)
     gene            complement(3757..3833)
                     /locus_tag="RH288_001753"
     tRNA            complement(3757..3833)
                     /locus_tag="RH288_001753"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3797..3799),aa:Arg,seq:ccg)
     gene            complement(3936..5321)
                     /locus_tag="RH288_001754"
     CDS             complement(3936..5321)
                     /locus_tag="RH288_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV4030811.1"
                     /translation="MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVA
                     GVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAA
                     IASHPFRSILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGL
                     NRHGKAHKLEE"
     gene            complement(5512..6252)
                     /gene="rffM"
                     /locus_tag="RH288_001755"
     CDS             complement(5512..6252)
                     /gene="rffM"
                     /locus_tag="RH288_001755"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HDV4030812.1"
                     /translation="MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAI
                     NAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMA
                     RAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
                     AQIVTVAMGSPKQEIIMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWL
                     YRLLSQPSRIKRQLRLLRYLRWHYTGNL"
     gene            complement(6255..7607)
                     /gene="wzyE"
                     /locus_tag="RH288_001756"
     CDS             complement(6255..7607)
                     /gene="wzyE"
                     /locus_tag="RH288_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HDV4030813.1"
                     /translation="MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPR
                     RPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
                     "
     gene            complement(7604..8683)
                     /gene="rffT"
                     /locus_tag="RH288_001757"
                     /gene_synonym="wecF"
     CDS             complement(7604..8683)
                     /gene="rffT"
                     /locus_tag="RH288_001757"
                     /gene_synonym="wecF"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HDV4030814.1"
                     /translation="MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDD
                     GLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPS
                     QFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
                     LYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVP
                     MGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKN
                     TIAFFSPNYLQGWQRALAIAAGEVA"
     gene            complement(8680..9930)
                     /gene="wzxE"
                     /locus_tag="RH288_001758"
     CDS             complement(8680..9930)
                     /gene="wzxE"
                     /locus_tag="RH288_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HDV4030815.1"
                     /translation="MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFR
                     QLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVVGTSSAMVLGFSTLMALVFVLAA
                     APISQGLFGNTDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
                     LAYYVSYRLGGYEGALLGLALIPALVVIPAAIMLIKRGVIPLSYLKPSWDNGLAGQLS
                     KFTLMALITSVTLPVAYIMMRKLLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIWLLLSNKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEVSQFTLLMVFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(9932..11062)
                     /gene="rffA"
                     /locus_tag="RH288_001759"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(9932..11062)
                     /gene="rffA"
                     /locus_tag="RH288_001759"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HDV4030816.1"
                     /translation="MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRP
                     DTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGR
                     IELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGEHFG
                     EFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS"
     gene            complement(11067..11741)
                     /gene="rffC"
                     /locus_tag="RH288_001760"
                     /gene_synonym="wecD"
     CDS             complement(11067..11741)
                     /gene="rffC"
                     /locus_tag="RH288_001760"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HDV4030817.1"
                     /translation="MPVRASIEPLTWENAFFGVNSAIVRITSEAPLLTPDALAPWSRV
                     QAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASA
                     AFAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
                     TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVEST
                     AYWLYR"
     gene            complement(11719..12600)
                     /gene="rfbA"
                     /locus_tag="RH288_001761"
     CDS             complement(11719..12600)
                     /gene="rfbA"
                     /locus_tag="RH288_001761"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDV4030818.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT
                     GYGQYLLELLRARPRQY"
     gene            complement(12619..13686)
                     /gene="rffG"
                     /locus_tag="RH288_001762"
     CDS             complement(12619..13686)
                     /gene="rffG"
                     /locus_tag="RH288_001762"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDV4030819.1"
                     /translation="MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSL
                     APVAQSERFAFEKVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYG
                     NGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPN
                     KPHGVVHYSDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLAN
                     ESWWKQVQDGSYQGERLGLKG"
     gene            complement(13686..14948)
                     /gene="wecC"
                     /locus_tag="RH288_001763"
     CDS             complement(13686..14948)
                     /gene="wecC"
                     /locus_tag="RH288_001763"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HDV4030820.1"
                     /translation="MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVPTPFKGDHEPDMTYVESAA
                     RSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICADQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNI
                     DDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVM
                     LVDHSQFKVINGDNVHQQYVVDAKGVWR"
     gene            complement(14945..16075)
                     /gene="wecB"
                     /locus_tag="RH288_001764"
     CDS             complement(14945..16075)
                     /gene="wecB"
                     /locus_tag="RH288_001764"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDV4030821.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLD
                     QVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
                     VADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESF
                     GRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVE
                     EVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL"
     gene            complement(16131..17177)
                     /gene="wzzE"
                     /locus_tag="RH288_001765"
     CDS             complement(16131..17177)
                     /gene="wzzE"
                     /locus_tag="RH288_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HDV4030822.1"
                     /translation="MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIA
                     LAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYK
                     EFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDS
                     VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKA
                     IYDRRMNSIEQALKIAEQHNISRSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGP
                     AFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGG
                     LIGAGVALTRRCSK"
     gene            complement(17189..18292)
                     /gene="wecA"
                     /locus_tag="RH288_001766"
     CDS             complement(17189..18292)
                     /gene="wecA"
                     /locus_tag="RH288_001766"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HDV4030823.1"
                     /translation="MNLLTVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQ
                     GLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACAGVLVFIGALDDRFDISVKIRAT
                     IQAAVGIVMMVFGNLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWILLETTQGKTHPISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLIMRAGFTSRQAFVLITLAAALLASIGVLAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK"
     gene            complement(18532..19791)
                     /gene="rho"
                     /locus_tag="RH288_001767"
     CDS             complement(18532..19791)
                     /gene="rho"
                     /locus_tag="RH288_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDV4030824.1"
                     /translation="MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(19876..19977)
                     /gene="rhoL"
                     /locus_tag="RH288_001768"
     CDS             complement(19876..19977)
                     /gene="rhoL"
                     /locus_tag="RH288_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide RhoL"
                     /protein_id="HDV4030825.1"
                     /translation="MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR"
     gene            complement(20118..20447)
                     /gene="trxA"
                     /locus_tag="RH288_001769"
     CDS             complement(20118..20447)
                     /gene="trxA"
                     /locus_tag="RH288_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HDV4030826.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            20578..21843
                     /gene="rhlB"
                     /locus_tag="RH288_001770"
     CDS             20578..21843
                     /gene="rhlB"
                     /locus_tag="RH288_001770"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HDV4030827.1"
                     /translation="MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEY
                     IEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTD
                     LPKPLRLTRPRTGNGPRRTGAPRNRRRSG"
     gene            21977..23461
                     /gene="gppA"
                     /locus_tag="RH288_001771"
     CDS             21977..23461
                     /gene="gppA"
                     /locus_tag="RH288_001771"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HDV4030828.1"
                     /translation="MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAA
                     GLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQE
                     ILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
                     SMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQAL
                     QEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIF
                     TELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVA
                     ANFFDQVEKEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPA
                     QKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMT
                     LQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWSLEVH"
     gene            complement(23508..25529)
                     /gene="rep"
                     /locus_tag="RH288_001772"
     CDS             complement(23508..25529)
                     /gene="rep"
                     /locus_tag="RH288_001772"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HDV4030829.1"
                     /translation="MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     ANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGER
                     DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGTELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGY
                     EALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFP
                     YVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK"
     gene            25746..26195
                     /locus_tag="RH288_001773"
     CDS             25746..26195
                     /locus_tag="RH288_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDV4030830.1"
                     /translation="MAINFSPKVGEILECNFGNYPVSQNGQFSTTYYNGRIPPEMIKN
                     RLVVVLNGKINGNACIVVPLSTTRDHDKLNRGMHVEIASNVINDLQFFDQQIRWAKAD
                     LVQQVSRNRLNRARTYRGYLNQCLPHELVADIQRAVIKSINAISLIN"
     gene            26394..26675
                     /gene="ppiC"
                     /locus_tag="RH288_001774"
     CDS             26394..26675
                     /gene="ppiC"
                     /locus_tag="RH288_001774"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004097481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HDV4030831.1"
                     /translation="MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSG
                     KRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN"
     gene            complement(26721..28196)
                     /gene="ilvC"
                     /locus_tag="RH288_001775"
     CDS             complement(26721..28196)
                     /gene="ilvC"
                     /locus_tag="RH288_001775"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDV4030832.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     INLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
                     GAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            28346..29239
                     /gene="ilvY"
                     /locus_tag="RH288_001776"
     CDS             28346..29239
                     /gene="ilvY"
                     /locus_tag="RH288_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HDV4030833.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSVEKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPM
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCA
                     QKKRLHEPLIEAFWKILPNHK"
     gene            complement(29291..30835)
                     /gene="ilvA"
                     /locus_tag="RH288_001777"
     CDS             complement(29291..30835)
                     /gene="ilvA"
                     /locus_tag="RH288_001777"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HDV4030834.1"
                     /translation="MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEER
                     KEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRF
                     LNTLGTYWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAF
                     RFFLAG"
     gene            complement(30838..32688)
                     /gene="ilvD"
                     /locus_tag="RH288_001778"
     CDS             complement(30838..32688)
                     /gene="ilvD"
                     /locus_tag="RH288_001778"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDV4030835.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIG
                     ILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFS
                     QDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELA
                     ARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(32753..33682)
                     /gene="ilvE"
                     /locus_tag="RH288_001779"
     CDS             complement(32753..33682)
                     /gene="ilvE"
                     /locus_tag="RH288_001779"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HDV4030836.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIF
                     VGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     gene            complement(33702..33965)
                     /gene="ilvM"
                     /locus_tag="RH288_001780"
     CDS             complement(33702..33965)
                     /gene="ilvM"
                     /locus_tag="RH288_001780"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HDV4030837.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQN
                     INIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA"
     gene            complement(33962..35608)
                     /locus_tag="RH288_001781"
     CDS             complement(33962..35608)
                     /locus_tag="RH288_001781"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HDV4030838.1"
                     /translation="MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAP
                     FIGTDAFQEVDVLGLSLACTKHSFLVQSLEELPRIMAEAFDVACSGRPGPVLVDIPKD
                     IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVPALRE
                     FLAATKMPATCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPHASVIHMDIDQAEMNKLRQAHVALQGDLNALLPALQQPLNINDWQQHC
                     AQLRDEHSWRYDHPGDAIYAPLLLKQLSDRKPADCVVTTDVGQHQMWAAQHIAHTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIPGQHITRKDQVEAAL
                     DTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(35611..35661)
                     /locus_tag="RH288_001782"
     CDS             complement(35611..35661)
                     /locus_tag="RH288_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030839.1"
                     /translation="MNNSTKFCFSRFRTGN"
     gene            complement(35747..35845)
                     /gene="ilvL"
                     /locus_tag="RH288_001783"
     CDS             complement(35747..35845)
                     /gene="ilvL"
                     /locus_tag="RH288_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HDV4030840.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            36198..37718
                     /locus_tag="RH288_001784"
     CDS             36198..37718
                     /locus_tag="RH288_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDV4030841.1"
                     /translation="MSLSIVHTRAALGVNAPPITVEVHISKGLPGLTMVGLPETTVKE
                     ARDRVRSAIINSGYEYPAKKITINLAPADLPKEGGRYDLPIAIALLAASEQLTANKLD
                     EYELVGELALTGALRGVPGAISSATEAIKSGRKIIVAKDNEDEVGLINGEGCLIADHL
                     QAVCAFLEGKHALERPKPTDAVSRALQHDLSDVIGQEQGKRGLEITAAGGHNLLLIGP
                     PGTGKTMLASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSASLT
                     AMVGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITY
                     PARFQLVAAMNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDLSLEIPLPPPGI
                     LSKTVVPGESSATVKQRVMAARERQFKRQNKLNAWLDSPEIRQFCKLESEDEMWLEGT
                     LIHLGLSIRAWQRLLKVARTIADIDQSDIITRQHLQEAVSYRAIDRLLIHLQKLLT"
     gene            complement(37743..38081)
                     /gene="maoP"
                     /locus_tag="RH288_001785"
     CDS             complement(37743..38081)
                     /gene="maoP"
                     /locus_tag="RH288_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HDV4030842.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNE
                     LDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTDSDD"
     gene            38200..39039
                     /gene="hdfR"
                     /locus_tag="RH288_001786"
     CDS             38200..39039
                     /gene="hdfR"
                     /locus_tag="RH288_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HDV4030843.1"
                     /translation="MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLG
                     VNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWEC
                     MLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
                     LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQ
                     IAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLD
                     EVY"
     gene            complement(39135..39210)
                     /locus_tag="RH288_001787"
     tRNA            complement(39135..39210)
                     /locus_tag="RH288_001787"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39175..39177),aa:Trp,seq:cca)
BASE COUNT         9626 a        10676 c         9878 g         9036 t
ORIGIN      
        1 gccttacata tcaactgcgc cagaggtagg attgaaaacg ctctcctgat tttccaattc
       61 attttctgga taaataaata atttattttt gtcactatta tttatgtaat catcctgtca
      121 gggagaggga tctcaattat caatgcttaa ttacgtcatc attttgatga catgaaaccg
      181 gagcattttg catggaaatt tcgttttcac ccaaacgtct tgttgttgct gtcgccgccg
      241 ctcttcctct catggccagc gcagcagata ccccgtcaac tgccaccgca cgcaaaggct
      301 ttgccggata cgatcaccca aaccagtatc tggttaaacc ggcgaccact attgccgaca
      361 acatgatgcc agtaatgcag catccggcgc aggataaaga aacccagcag aagctggcag
      421 aacttgagaa aaaaaccggt aagaagccca atgtggttat cttcctgctg gacgatgtgg
      481 gctggatgga cgtcggtttt aacggtggcg gcgtggcggt gggtaaccct acaccagata
      541 tcgatgcagt tgccagccag gggctgattt taacgtcggc gtattctcaa ccaagctctt
      601 ccccaacccg cgccaccatt ctcaccggac aatactccat ccaccacggc attctgatgc
      661 cgccaatgta cgggcaaccg ggaggtctgc aagggttaac caccctgccg caattgctgc
      721 acgaccaagg ttacgtcacc caggctatcg ggaaatggca tatgggggaa aacaaagagt
      781 cgcagccgca gaacgttggc tttgatgatt tccgtggctt taactcggtg tctgatatgt
      841 acaccgaatg gcgcgacgtt cacgtcaatc cggaagtggc cctgagtccg gaccgttctg
      901 aatacatcaa gcaattaccg ttcagcaaag atgatgttca tgcagtgcgc ggcggcgaac
      961 aacaggccat tgccgacatt acgccgaaat atatggaaga tctggatcaa cgctggatgg
     1021 aatatggcgt taagttcctc gacaagatgg cgaagagcga taagcctttc ttcctctatt
     1081 acggcactcg cggctgtcac ttcgataact acccgaacgc taaatatgcg ggtagctctc
     1141 cggcacgcac ctcgtatggc gactgcatgg tggagatgaa cgatgtgttc gctaatctgt
     1201 ataaaacact ggagaaaaac ggtcagcttg ataacacgct gatcgtcttt acctccgata
     1261 acggaccgga agccgaagta ccgccgcacg gacgcacccc gttccgtggt gcgaaaggtt
     1321 cgacctggga aggcggcgtt cgcgtaccga ctttcgttta ctggaaaggg atgatccaac
     1381 cgcgtaaatc tgacggtatt gtcgatctgg cagatctctt ccctaccgcg ctggatctgg
     1441 cagggcatcc tggagcgaaa gtggcgaatt tagtgccgaa aaccaccttt atcgatggtg
     1501 tggaccagac atccttcttc ctgggaacaa atggtcagtc taaccgtaag gccgagcact
     1561 acttcctcaa cggtaaactc gctgctgtgc gtatggatga gttcaagtat cacgtcctga
     1621 ttcagcaacc ttacgcttat acccagagcg gatatcaggg tggattcacc ggcacagtaa
     1681 tgcaaacggc gggatcgtcg gtgtttaacc tctacaccga tccgcaggaa agcgactcca
     1741 tcggcgtgcg ccatattccg atgggtgtac cgctacagac cgaaatgcac gcgtatatgg
     1801 agatcctgaa aaaatatcca ccacgcgcgc agattaaatc tgactaagcc ggcgctatcg
     1861 ctgagatctg cctttgccgg atgcgatgct gacgcatctt atccagccta cagaacgctg
     1921 caatttattg aatttgcacg atcatgtagg ccggataagg cgtttacgcc gcatccggca
     1981 atcaaccgca ggcggccaca aaatggccgc ttttttactt actcaccacc agcaaatgcg
     2041 catgcataat gtcgctggcc gggcggccat gcgccagcaa atcagacatt gctttaagat
     2101 acggcggcag atggcgaaaa taacgctgat acccggcaca taaataattc agcccaggct
     2161 tgccgctggc atcgagcata aagcggtgtt tcgggcagcc tccccagcac gcttttaaca
     2221 cgttacaact acgacactgc gccggtaact gcttaaattt atcttcacca aacacctgct
     2281 gttgcgggga atcgatcatt tctgcaattg tttgctggtg catattcccc agccgatatt
     2341 gcggataaac atagtgatcg caggcgtaaa cgtcgccatt gtgctcaaca atcaccgagc
     2401 gcccacaggt tggctgatga tggcaaaccg cacccggcgc accgacaaaa ttggcaaacg
     2461 cccattcgat attcatcacg aaaatcttgc cgacgtcgcg tttgatccag tggtcaaaaa
     2521 tcgccaccag aaattcacca aattcatcgg ggcgcacaga ccattccgtt agctcaccct
     2581 gaatatcacc aggcgcatgc aatttcagtc cttcgcgggc agccgtttca tcagccaggc
     2641 gctcgaccac cggaataaac tggatgaatt ccactcccgc atcgcacaaa aaatcatata
     2701 cctgcaacgg ttgctgcgcg ctggtgcgat taacgcagac cagcacgtta tagtcgacat
     2761 gatgtttttg caggaacgtc agggcacgca tcaccagctt atgcgtgggt ctgccacctt
     2821 tagtcacgcg atattgattg tggatctcag gcgggccatc cagcgataaa ccaacaagaa
     2881 aatgatgctc cgcgagaaac gcgcaccatt cgtcatccag cagcacgccg ttagtctgga
     2941 agctgttact tatcttcctg ccagcaccat atttcgcctg tagcgctacg gcacggcggt
     3001 aaaactccag cccgagtagc gttggttcgc cgccctgcca ggtaaaagcc acttcgtttt
     3061 gcggttcgct ggcagcgata tagtgacgga catacgcttc cagcgtgtca tcgtccatat
     3121 gcgtgactgg cttttcgcgg taaagggatt gtttttcgag ataaaaacag tagtcacagt
     3181 tcagattaca atcggaacca ctcggtttcg ccatcacatg aaaagcacgc gttggaacct
     3241 gttgcagcat ggtcactcct tgcctgaagt catccttcaa tacgttaagg gcgaaatcat
     3301 accgtggggc aatgagttat tacgggcgtt tattgcgaag ggagggtgac gaaatgcaca
     3361 gaaaacaaaa aaccccgccg aagcggggtt caaaattggt cggcgagaga ggattcgaac
     3421 ctccgaccca ctggtcccaa accagttgcg ctaccaagct gcgctactcg ccgaaatact
     3481 gctttttgaa tttttagttc aattctttaa agtcgtggtg cgaggggggg gacttgaacc
     3541 cccacgtccg taaggacact aacacctgaa gctagcgcgt ctaccaattc cgccaccttc
     3601 gcattgtcac aacttctaat aatggggtgg ctaatgggat tcgaacccac gacaactgga
     3661 atcacaatcc agggctctac caactgagct atagccacca ctacaaatct tgttacgcgg
     3721 tattactacc accgcagctc aagcgccggg actaaatggc gcgcccgaca ggattcgaac
     3781 ctgagacctc tgcctccgga gggcagcgct ctatccagct gagctacggg cgcttagcgc
     3841 cgttgcgggg gtggataata cggacttccc acccctctgt ctagtccctt tttaaataaa
     3901 ttgcgcgttt ggttacggtt tgtgcgtttt gctgcttatt cctccagttt atgcgctttc
     3961 ccgtggcgat taaggccaaa aactttataa atcgccgtca ccgccagcat aaagatgatg
     4021 ccaacaaaca gcgacatacg cgtatcttca ttaaagtaca tgccgatcaa aacgcaaatc
     4081 aggaatgcca ttgttacgta attggcccac gggaacagga ttgagcggaa cggatggctg
     4141 gcaatcgccg ctttatgtgc acgccgaaaa cgcagctggc ttatcaatat cacaaaccat
     4201 ggcaccatcc ccggaagcac gctggcactg tagacgtaga caaacacacg ctgcggattg
     4261 ggaatgatgt agttcaggca tgagccaatt agcagaatag caatagatac tgccacaccc
     4321 gcaaccggta cgccgtgacg ggaaactttc gccattgccg ccggtaactg acggtttttc
     4381 gccagtgcgt agagcatacg tccgcaactg tacatgccgc tgttacagcc agagagcgca
     4441 gccgtcagca ccacaaagtt gataatgccc gccgctgcgg taataccgat tttggcaaaa
     4501 gtcagtacga acgggctgcc gttgctgcct atttcattcc acgggaagat ggtgacgata
     4561 acgaaaatcg cgcctacgta gaaaatcagg atccgccaca gcaccttgcc tacggcactg
     4621 cgcagcgtca cctgcggatt cttcgcttca ccggcagtaa tgccaatcag ctccacgccc
     4681 tggtaggacg ccaccacaat acacagagcg gtcaggaacc ctttccagcc acccgcaaag
     4741 aaaccgccat gctctgtgag attgctaaaa ccaatcgact gcccgccatt gccaaagcca
     4801 aagaaaatca cgcccaggcc aatgacaatc atcacgataa tcgtggtgac tttgatcatc
     4861 gcgaaccaga actcgatttc gccgtacaac cgcaccgccg ccagattcgc caacgccacc
     4921 agcgccactg cgatcaatgc gggtatccac tgcgccatct ccgggaacca gaactggaca
     4981 taaacgccaa tggcggtgat ttcagagatc cccaccgcca tccacataaa ccagtaagac
     5041 caggcggtga gatagccaaa gaacgggctc atataacgat gcgcataaac ggcgaacgaa
     5101 ccggtaaccg gttcgaggaa caacatttcg cccattgaac gcatgatgaa aaagacgaac
     5161 agcccggcga tgatataggc caacaatacg gatggcccgg cccatttcag ggtactggcg
     5221 gcccccataa acaggccgac gccaatggtg ccccccaggg cgatgagttc gatatgtcga
     5281 gcttccagcc cacgctgtag ctctggtttg ttatctgcca taaatcctcg tgttgtgttt
     5341 gcatgctttc cggtgttacc ggttatcgtt atgggtacat cgagtgttgc aaatgttttc
     5401 gtaattcagg agaaatggca aataaagcat taaaaatttg aatgctttgt gtaataaaaa
     5461 agcagacagg cgacggagtg accactccgt cgctttacaa agagaggaaa atcataggtt
     5521 gccggtgtag tgccagcgta aataacgcag caaacgaagc tgacgcttaa tgcggctcgg
     5581 ctgcgaaagc aggcggtaga gccactccag ccccagcgtt tgccagattt tcggtgcgcg
     5641 ttttacgtga ccggtgaaaa catcgtaagt cccgccaacg cccatataca gcgcatctgg
     5701 atgtaccaga cggcagtcgc gcatgatgat ctcctgcttt ggcgatccca tcgcaacggt
     5761 gacgatttgc gcaccgctgg catgaatgcg ttcaaacagc gcctgacgct gctcgggttt
     5821 aaaataacca tcctgactgc caacgatatt cacattccac tggttgcgca gtttagcttc
     5881 agtttgcgcc agcacttcag gtttaccgcc cacaagaaat accggcgtcc cttctttgcc
     5941 tgcgcgcgcc atcagctctt cccagagatc ggcaccggca acgcgggaaa cctgcgcctg
     6001 cgggtacttt ttacgtactg aacgtacaac gctgatgcca tccgcatatt taaattcggc
     6061 agcgttaatt aactccctga cctcggcgtt atcttcaata gtcagcattt tttcagcatt
     6121 aatggcaacc agcgttccct gcttaagctg cccgtcagca aacagataat cgagggcgtg
     6181 ctgcatatca cgccaaccaa tcaactgtaa gccacgcagc gtataggttg gtgccgtggt
     6241 gttgttattc attgttatcc ttcaacctgc gtccggagcg atgattttgt acgtttatga
     6301 atgagtccgg cgctttcaaa aagccagtac aacagttttg cgatcatcag acatgcgccg
     6361 aagaccacga taaaaaagac cacgcgtgag acaaacgaat ccagcccttc acgcgccagc
     6421 acgatcatat tgaagatcgc cccaaagcag aaactgtgca atatcgcagc tttatagcga
     6481 ttaggctcgc ggttgcccag ctcatacagc cagtcgaacc atttgatgat cagaccaacc
     6541 acgatcgccc cgagcgggat gaacaacgcg ccgcccatca ccaccagtga gcctataagc
     6601 gtaggcgaga tcgccagtcc ggagtggtta ttcagcactt cccaggtaaa gtagttggct
     6661 gagttcagca ccatactcgg gcgacccggc cacagccagg aagggataaa gacatagaaa
     6721 tcgcggacaa ttggagccag gccctggaag tcgatgttgt cgtagttctg caacagcaac
     6781 gccagattct cccacggcga gaaggtgtcg cgagtgagat agagaaacgt atagaacgct
     6841 tcatcgccgc tcacattcat tccatagcgt tttagtgcca gccagaacat gccaacaatc
     6901 cccagcacgc ccgccgccgc cagcatccac aacgaaatcc agccgcgaat aatgccaata
     6961 aacaggaaga tagcgaatgc gatgatgata ttggcgcgag tgccgccgac aatcatataa
     7021 gtcagcaagc caaaggcgac cgtgctgacg aggaaaaaca gccacgcttt gctgtcctgg
     7081 cgcagaaagt agaccaccag catcgccggg atgaaaaagt aaaagaagcg ttttaacgcc
     7141 acgccggaga cttcactgga aaagatctga ctgtaggagt taagccggaa cagcaaaaag
     7201 ccgttgtgca tgaagaagat gccgacgctt accagcgcga tacccatcag gatcacccac
     7261 gtaagattgg tctccacgcg gttcatggta aacagcggac ggcgcggtac atcagcaacg
     7321 cgtttgcgta ggcgggtttt gtaggtgaca tagtaaaccg cgtagaagca gcccgcagaa
     7381 agcaacgcct gcaacaagat ttctggcggc gcgacaccaa catcaaagcg aaataccagc
     7441 acgctggtca gcgggaagcc gaagaaaaag gtgagcaaaa acagcaatga aaagaagaca
     7501 ttgaagttaa agcgcacacg gcgaaactca aaccaggtca gcgtggcaat aaacagcgtg
     7561 cagagcagcc agacaacaaa caggccactg aattgcagca gactcatgcg acctccccgg
     7621 cggcaatcgc caacgcccgc tgccagcctt gtagatagtt agggctaaag aaggcaatgg
     7681 tgtttttatc caccgacgcc aactggcgct gcgcttcacg cacaatatcc tcgttgagat
     7741 cgtcggtagt aaacagcacc ggcaaatgtt gttccgtcat atcctgccag aacggatttt
     7801 cccggttaag cacacaagga atgcccgcct gaatcagtaa gcacagcgta ccaatgccct
     7861 gctggcgggc aaaaataaag taaccaagat cgcactgacg aagtagcgcc agataggcgt
     7921 caaattccag tttttcgctc agaatttgta gattttcttc gctgaataac tccagccccg
     7981 cctgacgaac ttcctcaatg tacgcttcgt tattaggcgg atatcccatc ggcaccacca
     8041 cttttaccgt atcgccaaat tgctgatgaa cggcgcgcaa ggcagcaata tgctcattgc
     8101 tgcggtcgcc ggagttcccc accagaatgg tcattttccc ttcacgttgc cgatcgttcg
     8161 ccatcgtatt gagcgaaggg tccatccgcg tcgggaagta cagcagttcg ccccgcacct
     8221 ttgggtgcgt tttggcaaaa aagctcaaat cgccgcgggt ggcaaataca cagccgactc
     8281 gcttttgcgc caggcgacgt agtgggtaaa aaagcttata tctcaagcca ctggaaagct
     8341 catacaggtc tgccccccag atatgccaga aaaactggct gggcttaatg ccaccactca
     8401 gcagagccag ccacagtgtg ggattgaact gaccgtggaa gaaaaaacgc tgctgacggt
     8461 tagcttttgc tttcgcgatg accgcttccg ccagcgattt tttcccaggg aaaaattgca
     8521 cagaaagcgc cggacagcta tcacttaagc cgtcgtcctt gccaacaacc ataaactcgc
     8581 gcgcgtgctc gctcgtcgcg gccagcgcgt cattgaaaaa ccgcaaaacg gttcggttat
     8641 ggtgagggat atccgatccc agtacgtgaa tcagtacagt catgcccgcc tacgccagag
     8701 taaaaacacg ccacaacaaa gagaaaaata gacgatataa gttgccatat atgcctgcgc
     8761 cgcgcccagt gcaccatgcg cagggattag ccagtgggca aataccatca ataaagtgaa
     8821 ctggctgact tccgccagaa tataaaaccg cagtgacgct ttggcgatca ccagataacc
     8881 aaagacataa gcgcccactt ttaacacatc acccactaac tgccaggcaa agagatcgcg
     8941 catagcggta aatttattcg acaacagcag ccagatagca aaatcacgca gcagccagac
     9001 ggtaaaactc gccgccgcca ctgccggtaa gacgaatttc agcgatttaa ccacttcccg
     9061 ggtgatatcg cgcttttccg ttagccgcga caacgtgggc agcaaatata cgctgaacga
     9121 tgccgtaata aattgcaggt aggcatcgga aatactgctc accccttgcc agatccccac
     9181 ctcatcccag ctatactgcg ccgccagcag tttacgcatc atgatgtaag caacaggcaa
     9241 ggtcaccgac gtaatcaacg ccatgagcgt aaatttgctc aactgccctg ccagaccgtt
     9301 atcccagctg ggtttcagat agcttaacgg gatgacacca cgtttgatca acatgatggc
     9361 ggcaggaatt accaccagcg cgggaatcag cgccagaccc agcaacgccc cttcataacc
     9421 gcccaaacgg taactgacgt agtacgcgag aacgccaatc aagctgccga caatcagcga
     9481 taacgcatta cctgcggcat cgcgaaagcc tttcatcagc gccagtaaca ggttgcccca
     9541 ggcgatcccc atttgcacca gcgccactaa acgcaccagc ccctgatagt cggtattacc
     9601 aaacaatccc tggctgattg gcgcagctgc cagcacaaaa accagcgcca tcagcgtaga
     9661 gaaaccaagt accatcgctg atgaagtgcc gaccacgcgg cgcagctgtt gcggattatc
     9721 atggtactgg gcaacgtatt tggttacacc gttaaagatg ccagccccgg caagcacgcc
     9781 gagcacggta atcaactggc ggaaatttgc cgccagccca agccccgccg gaccaaatga
     9841 caccgccagc aacttaccga ccagtaaccc ggcaccaatc ttgaccagtg tactggccgc
     9901 cgtccacaag gacgcttttg ccaacgacat atcaggaaaa gtagttcaac aaagtcgcaa
     9961 ttaccgtacg ctgattgacg ggcgacaggt tgtagaacag cggcaggcgc agcaggcgct
    10021 cgctctcttt ggtggtgtag cgatcttcac cgtggaactc accaaagtgt tcccccgcag
    10081 ggcaaccgtg cagcggaatg taatgaaaca ccgccatgat ttccgcttct ttcagaaagt
    10141 taatcaacgc gctccggtca tcaatatccc gcagtttaat gtagaacata tgcgcgttct
    10201 gcacgcagcc atcgggaatc gacggcagct cgatacgccc ggctttcgcc agaggcgcta
    10261 acgcatcgta gtagttttgc cacagcgcca gacgttgctg gttgatacga tccgctgctt
    10321 ccagttgcgc ccacaggtat gcagcttgca gatcggacat caaatagctg gagccaatat
    10381 cgcgccaggt atatttatcg acctgaccac ggaagaactg gctgcggtta gtgccctttt
    10441 cacggatgat ctcggctcgt tcgatcaacg ctttatcgtt aatcagcgtc gcgccgcctt
    10501 caccgcccgc cgtgtagttt ttggtttcat ggaagctaaa gcagccaata tgaccaatgg
    10561 ttcccagtgc acgccctttg taagtggaca tcacgccctg agcggcatct tctaccacaa
    10621 acaaattatg ctttttcgcc aacgccataa tggtgtccat ttcgcaggcc acacccgcgt
    10681 aatggaccgg cacgataacg cgcgttttgt cggtgatcgc cgcttcaatc agcgtttcgt
    10741 cgatgttcat ggtgtccggg cgaacatcca caaaaacgat ttttgcgcca cgcagcacaa
    10801 aggcattggc ggtggagaca aaggtgtagc tcggcatgat cacttcatcg ccaggctgga
    10861 tatcgagcag cagcgccgcc atctccagcg aagcggtgca ggacggcgtc agtaacactt
    10921 tggcgctgcc aaaacgttgc tccagccact gctggcagcg acgggtaaaa ccgccatcgc
    10981 cacacagttt gccgctaccc attgccgact gcatatagtc gagttcggtt cccaccaccg
    11041 gcggtgcgtt aaatggaatc atgtgatcac ctgtataacc agtacgcggt gctttctaca
    11101 ttcgcaccac tttgtatgta tcgtttaagc gcggcggtgt tgcccatttg ggtcgccacc
    11161 cgcaaagttg ttttaccgcg agcatacgcc cagtttagcg ccgtttgcat cagctcagca
    11221 cctgcaccgc gtccagccag caggccaatt cgcgcatctg tcgcattgag ttcccgtaaa
    11281 gagacatagc cgcgaatatc gccggacgcc gcacgtaaaa tcagacattg atgatcaaag
    11341 gtgccgcgca cggcattttc aatccactgt gcataaaagc gactgctggc gtcaggcgca
    11401 taccacggcg cacgaaaacg gctttgcgca aatgcggcgc tggctaactg acgtaatgcg
    11461 ggaatatcgg tctcttgtgc cactacagca ccgctatcac tggcattgtt cacgggtagc
    11521 gccaaatcaa cttcaccttc taccagggag aatcccagct gttgcagggc atccagttca
    11581 cccgtatttg atgccgcaat tttggcctgc acccgtgacc acggcgctaa cgcgtctggc
    11641 gtcaggagcg gtgcttcaga cgtaatgcgc acgatggcgc tgttaacacc aaagaaggcg
    11701 ttttcccagg ttagtggctc aatactggcg cggacgggca cgaagtaact ccagcagata
    11761 ttggccgtag ccagttttcg ctaatgaact ggcagcacgc ttcacaccct cgtcatcgag
    11821 ccagccgtta cgccaggcaa tctcttccag gcaggcaatc ttaaagccct ggcgtttttc
    11881 caccgtctgt acaaaggtgc tggcttcaat caggctgtcg tgagtgccgg tatccagcca
    11941 ggcaaatccg cgcccgagca gttcaacggt caggttgccc gcctcgaggt acatctggtt
    12001 gatggaggta atctccagtt caccacgctc cgacggcttc acctgctttg cgtactccac
    12061 gactttactg tcgtagaaat aaagcccggt caccgcccag tttgacttcg gctgttttgg
    12121 cttttcttcc agcgagatag cgcggaaatt gtcgtcaaac tccaccacgc caaagcgttc
    12181 cgggtccatc acctgatagc caaaaaccgt cgccccttcg gtgcgcgccg caacatgacg
    12241 cagcttcgga ctgaagccct gaccgaagaa gatgttatcg cccagcacca gacaagaagg
    12301 ttcaccatta aggaaggttt caccgatgat aaaggcctgc gccagaccgt ccgggctggg
    12361 ctgttcggca tattccagct ggataccgaa ctcactacca tcgcccagca ggcgctggaa
    12421 ataaccttta tcttccggcg tagtgatgat gagaatttcg cggataccgg ccagcatcag
    12481 caccgacagc ggatagtaaa tcattggctt atcgtaaatc ggcaacagtt gcttcgatac
    12541 gccgcgcgta atcggatgca atcgggtgcc ggaaccgccc gccaggataa tacctttcat
    12601 gtttgcctcc gctgaaaatt agcctttcag acctaaacgc tcgccctgat agctgccgtc
    12661 ctgcacctgc ttccaccagc tttcattagc cagataccac tgcaccgttt tacgcattcc
    12721 actttcaaag gtttcctgcg gcagccagcc aagttcacgg gcaattttcg aagcatcaat
    12781 ggcataacgc agatcatgcc ccggacggtc agcgacaaag gtgatcaagt cactatagtg
    12841 caccacgccg tgcggcttgt tcggagccag ttcttccagc agctcgcaaa tggtttccac
    12901 aacatcgaga ttcttacgct cgttgtgacc accaatatta taggtttcac cgactttccc
    12961 ggtggtcgcc acgcaataca gcgcgcgggc gtgatcttcc acatacagcc agtcacggat
    13021 ttgctgcccg ttgccatata ccggcagcga tttacccgcc agcgcgttga ggatcatcag
    13081 cgggatcagt ttttccggaa agtggtaagg gccgtagtta ttcgagcagt tggtgataag
    13141 cgtcggcaga ccataggtcc gcagccaggc gcgcaccaga tggtcgctgc tggcttttga
    13201 cgcggaataa gggctgctcg gcgcatacgg cgtggtttcg gtgaagaaat catccgtcga
    13261 gtgcaggtca ccatatactt cgtcagtgga gatatgatga aaacggaacg ctgatttttt
    13321 atcttccgtc agcgcattcc agtaagcccg cgccgcttca agcaatgtat aagtcccgac
    13381 aatgttggtt tcaataaacg ctgccgggcc gtcaatagaa cggtcaacat ggctttcggc
    13441 tgccagatgc atgacacagt ctggctgatg ctcagtgaat acgcgtgcca gttctgcccg
    13501 atcgcagata tcaactttct caaaggcaaa gcgctcgctt tgcgcgaccg gtgccagcga
    13561 catcaggttt ccggcgtagg tcagcttatc gaccactacc accgcgtcgc tcgtttcgtt
    13621 gatgatataa cgcaccagcg ccgagccaat aaacccggca ccacctgtta tcagaatttt
    13681 tctcatcagc gccagactcc tttggcatcg acgacatact gctgatggac attgtcgcca
    13741 ttgataactt tgaactgact atgatcgacc agcatcacca gcacgtctgc cgttgccagc
    13801 gcctcgtcaa gctgcgccag agtacaaagc ccggtcagtt ttttcggcaa ctggtggatg
    13861 ttaggctcaa caaccagagt ttcgccgcta tgccactggg cgatcagttc agcgatttcc
    13921 atcgccgggc tttcgcgcag gtcatcaata ttcggtttaa acgccagacc aaagcaggcg
    13981 attttcagtt cactggcgcg tttatcggta gccgccaggc aatcagccac cgccgctttc
    14041 acctgatcga taacccagaa cggtttgtga tcgttcactt cgcgcgcggt acggataagc
    14101 cgcgcctgct gggggttctg tgccacgata aaccacggat caacagcaat gcagtgaccg
    14161 cccacgccag ggccaggctg aagaatatta acgcgagggt gacgattcgc caggcgaatc
    14221 agttcccaga cgttaatccc ctgatcggca caaatcagcg acaattcatt agcaaaagcg
    14281 atattcacat cgcggaagct gttttcggtg agcttacaca tttccgccgt ccgcgagtta
    14341 gtgacgacac actcaccttc gaggaaaatt ttgtacagtt cgctggcgcg ggccgaacaa
    14401 accggcgtca taccaccaat cacgcgatcg tttttaatca gctcgaccat tacctgtcct
    14461 ggtaacacgc gttccgggca gtaagcaatg ttgacgtccg cctgctcgcc cacctgctgc
    14521 gggaaagtga gatccggacg catctctgct aaccattctg ccatcttctc ggttgacccc
    14581 accggcgagg tggattcaag gatcaccagc gcgccttttt tcagcactgg cgcaatggag
    14641 cgagcagccg attcaacgta ggtcatatct ggctcatgat cgcccttaaa cggcgtgggt
    14701 acagcaatca gccaggcatc cgcttcaact ggcgtcgtgc tcgctcgtaa aaaaccgcct
    14761 tctacggcag tttttactac actcgccaaa tcaggttcga cgatatggat ttcgccacga
    14821 ttgatggtat caaccgcatg ttggttgata tcgacaccaa ttacctgttt ttgccgtgag
    14881 gcaaacgctg ctgccgttgg cagcccgata taacccagtc cgataacaga aatggtcgca
    14941 aaactcatag tgatatccga ttatttttta acgcttccag aatgcgagag catgcctgac
    15001 catcaccata cgggttatgg gcgcggctca tagcttgata ttcgttttcg tcttttaaaa
    15061 gacgcgtcac ttcctcgaca attcgctgct tatccgtgcc taccagacgc accgtacccg
    15121 ccgtcaccgc ttccggacgc tcagtggtat cgcgcatcac cagcacaggt ttccccagcg
    15181 aaggcgcttc ttcctgaatg ccgcctgagt cggtcaaaat cagccaggcg tggttcatca
    15241 gccagacaaa cggtaaatac tcctggggat cgatcagaat gacatttttc acatgcccca
    15301 gaatgcgatt gaccggctct ctgacgttcg ggttgagatg caccggatag acaatctgga
    15361 tgtcctggtg cgtggtggcg atgtctgcca gcgcgtggca gatttcttca aagccacgac
    15421 cgaaactctc acgcctgtga ccggtcacca gaatcatctt tttatcgggg tcgataaacg
    15481 ggtaatttgc cgccagttct gaacgcagcg tgtcgctgct catcacctgg tcacgcaccc
    15541 ataacagtgc atcaatgact gtattaccgg taatgaagat tcggctatcc gcaacgtttt
    15601 cacgcagcaa gttttgccgg gaagtttcgg ttggagagaa gtgatacatc gccagatgcc
    15661 cggtcaatgt acggttagcc tcttccggcc acggcgaata gagatcgccc gtgcgcagac
    15721 cagcctcaac gtgaccaaca ggaatacgct gataaaacgc cgccaggctg gttgccagcg
    15781 tcgtcgtcgt atcgccgtga accagcacga cgtctggttt gaactcggca agaataggtt
    15841 ttagcccttc cagaatccga caggttatct ctgtcaggcc ctgtcctggc tgcattatgt
    15901 tgagatcgta gtcaggtaca atggaaaaga gtttcagcac ctgatcgagc atctcccgat
    15961 gctgcgcagt gacgcaaact ttagcctcaa aaaaaggatc ttttgccaac gcatgcacca
    16021 acggcgccat cttgatggct tccgggcgcg taccaaatac agtcagtact ttcacatcga
    16081 ttctcttcga ataagcggcg agcgcctttg cgctcaccgc agcagtgttg ctatttcgag
    16141 caacggcggg ttaatgcgac accagccccg atcagccccc cgacaatgcc ccacataatc
    16201 atcaggaagg cacgacgtgg gctatcgcgt tttaccggtt cttccggcgt acgcaaatag
    16261 cgataggtct gaaaacgcgg atccagggtt ggaccaacat tcagggtgtt taacatggcc
    16321 cgattctgat catagtcgag atcaaaggcc ggaccgacgg cctgtaaatt ttccagtcga
    16381 gcctgaagca ttggacgccc aagcaggaac atttctgaat caggtaattc ctcggcaggt
    16441 acatctgtcg cactgcgcga aatattatgc tgctcagcaa ttttcagcgc ctgctcaatg
    16501 ctgttcatcc ggcggtcgta gatggctttc gccacctctt cctgacgctt cacctgagct
    16561 ttcatctgga tggtacgcgc cgcccatgcg cctttcagct catcattcag atggctggct
    16621 gcacgctggc tggcaaaagc aacatactga cgtaacaggt tattagcgtc aggcgcggtt
    16681 tcggcaataa gcttcacgct gtcattgacc gcgcgggtaa agtctccggg gataaactgg
    16741 atgttgttaa tcatttcatc cagcaacgcc gcatcggctt tgctgttgcc caccatccgc
    16801 tgtttgtaat agtcggtttg cagccagaac tctctgcggg tatcccacga ggccagttgc
    16861 ataacaaact ctttataggc ttcgtccatg accgatggtt ggtcggcaga agccatgttt
    16921 gaacggacat ccaggttacg caaaaattgc tgctgcgagt aatatccccc cagcatattc
    16981 accgttggac gatcggtaat cgccgtcgag ctccactcct gacgagcaaa aaacgtatac
    17041 gccagcgcga ttaacgcaaa cgccagcccc atgccaataa tccatagctt cccagcccac
    17101 aaggtacgaa acaacccacg aatatccagt tcattttcag cgtcttcggc cggtttccca
    17161 ggcattggtt gtgtcatcac atcctcattt atttggttaa attggggctg ccaccacgat
    17221 ttctacgcag tctgcgtttt acgcgcttaa taaagcgagc aactttccag gcacgcttaa
    17281 tgcaatatcc atagaggaag aatgctagca aaaagagcac cagcatgacc cactccggga
    17341 caaaatgaga atattctgcc agcacgccaa tggaagcgag cagtgctgcg gcaagggtaa
    17401 tcagcacaaa cgcctgacgg gaagtaaacc cggcacgcat gatcaaatgg tgaatatgct
    17461 gacggtcagg agagaatggg ctcatgcctt tacgcaggcg acggtacata atcgccacca
    17521 tatccattag cggaatggcg attatccaca aagcggtaac cgggctgatg ggatgggttt
    17581 tgccctgggt cgtttcgagc aggatccaga tcacggtaaa accaatcagc gtactgcccg
    17641 catcacccat aaagactttg tagcggcgac ccaggatacc aaggttaagc atgatatatg
    17701 gcaggatggc ggcgatcatc gcaaagcacc agattgcgag gctggtttgc ccgtcgaacc
    17761 acaaaatcat accgattgct gcaaacgaga cgcaggacaa cccgcccagc aagccatcaa
    17821 tgccatcaac catgttgaac gcattaatgg ccgcccagac ggcaaatagc gtcaggaagt
    17881 aaccaaacgg tccgagcacc atctcccagg agccaaagat ataacccagg ctactgagat
    17941 aaaggttgcc aaacaccatc ataacaatgc caacagcggc ctgtatggtg gcacggattt
    18001 ttacgctgat atcaaaacgg tcatccagcg cgccaatgaa aacaagcaca ccggcacaag
    18061 cgagatagag agatgcatgc ggaatatagt aatcgacaat tccgaacgtg aagcaaatcc
    18121 ctgcgtaaac cgaaataccc ccaacgagtg gtatcaaccc ctggtgacgt ttgcggaagt
    18181 ttggtttatc cactaaaccg actttttttg ccaccttacg ggcaaaaaac agaaacagtg
    18241 tcgtgaataa aaaaatactg atgagatcag tactcactgt cagtaaattc acaatgcatg
    18301 ctctcagaga aaattattag cagaagtata accacgaaga cctttattca gaagggaaag
    18361 tccgttccga acccaccagt cctgtgcaaa aattaaccat ttgatatgca aattgcataa
    18421 catgtcagca aattccagga attttcctaa catcgccagc gcggcattaa gattacagat
    18481 ataaaagcaa aacgccacgt aaacacgtgg cgtttttggc ataagacaaa tttatgagcg
    18541 tttcatcatt tcgaagaaat cgtcattggt cttggtcatg gccagtttat taatgaggaa
    18601 ttccattgca tcgatttcgc ccatcgggtg aatgattttg cgcaggatcc acattttctg
    18661 cagttcttcc tgagtagtga gcagttcttc tttacgggta ccggaacggt tgtagtcgat
    18721 agccgggaag acgcgttttt cagcgatctt acgagagagg tgcagttcca tgttgcctgt
    18781 acctttaaac tcttcgtaaa taacttcgtc cattttagaa ccggtatcga taagcgccgt
    18841 cgcgataatg gtcaggctgc cgccctcttc cacgttacgc gccgcaccga agaagcgttt
    18901 cggacgatga agggcattgg cgtccacacc accggtcaac actttacctg acgccggaac
    18961 aacagtgttg taagcgcgcg ccagacgagt gatggagtcg agcagaatga taacgtcttt
    19021 cttgtgctca accaggcgtt tggccttctc gatcaccatt tccgcaacct gaacgtggcg
    19081 agatgcgggt tcgtcaaagg tagaagcaac aacttcacct tttaccagac gctgcatctc
    19141 ggttacttct tccggacgtt cgtcgatcag cagaaccatc agcacacaat ccgggtggtt
    19201 gtaagcaatg ctctgagcaa tgttctgcag cagcatagtt ttaccggctt tcggcggtgc
    19261 cacaatcaga ccacgctgac cacgaccgat aggtgatgcc agatccagta cgcgagcagt
    19321 taaatcttca gtagaaccgt taccacgttc catacgcaga cgagagtttg cgtgcagcgg
    19381 ggttaagttc tcaaagagga ttttgttgcg ggcgttttca ggtttgtcga agttaacttc
    19441 gttaactttc agcagcgcaa aatagcgttc accttctttc ggcgggcgaa tcttaccaga
    19501 gatggtatca ccagtgcgga ggttgaaacg gcggatttgg ctaggggaaa cgtagatgtc
    19561 atcaggaccg gcgaggtagg agctgtctgc ggaacggagg aaaccaaatc catcctgcaa
    19621 tatctccagt acgccatcac caaagatatc ttcgccactc tttgcgtgct gcttcaggat
    19681 ggcaaaaata atgtcctgct tacgcatacg agccaggttt tccagcccca tattttcgcc
    19741 gagagtgatc agctcagaaa ccggcgtatt ctttaattcg gtaagattca tagtggtgtg
    19801 agttcttaaa cttggggtaa atctcgaact taatgttgtg aatggtatgg caggatcatc
    19861 catgcctgtt tacggtcatc gactcatgtc ttttcgctgc ctggtcacag gagagtacgc
    19921 agaactgaaa cgacaagacg gattgagtga cgagccagaa atctgttcac ttcgcattta
    19981 agataaaacg ggaagcgttg gaaattacaa gattcaaact taataaggta tgtttaatac
    20041 gaagtcaaca ctaagttagc atgactcacg ccgggcgtcc agtttttagc gacggggcac
    20101 ccgaacatga aattccctta cgccaggtta gcgtcgagga actctttcaa ctgaccttta
    20161 gacagtgcac ccactttggt tgccgccact tcaccgtttt tgaacagcag cagagtcggg
    20221 ataccacgga tgccatattt cggcgcagtg ccagggtttt gatcgatgtt cagttttgca
    20281 acggtcagtt tgccctgata ttcgtcagcg atttcatcca gaatcggggc gatcattttg
    20341 cacggaccgc accactctgc ccagaaatcg acgaggatcg ccccgtccgc tttgagtaca
    20401 tccgtgtcaa aactgtcgtc agtcaggtga ataattttat cgctcatata taactccaca
    20461 ggaataagcc tggcgtgttg gtttcgttgt tggtgtaaca ttaaccaact aaaggttgac
    20521 tttatttcac cggatacgct ttcgtaaagc aatagtaagc tgatattcta ccacactatg
    20581 agcaaaacac atttaacaga acagaagttt tccgacttcg ccctgcatcc gaaggttgta
    20641 gaagcccttg aaaaaaaagg gtttcataac tgtacgccca ttcaggcact ggcccttccg
    20701 ctgacgctgg cgggtcgtga cgtagccggg caggcgcaaa ccggtaccgg gaaaacgatg
    20761 gcgtttctta cgtcaacgtt tcattatctt ctctctcatc ctgcgattgc cgatcgcaag
    20821 gtgaatcagc cgcgtgcctt aattatggca ccgacgcgtg aacttgccgt gcagatccat
    20881 gccgacgcag aaccgctggc ggaagctact ggcctgaagc tgggtctggc ttacggtggt
    20941 gatggctacg acaaacagct gaaagtgctg gaaagcggcg ttgacattct gattggcacc
    21001 acggggcgtt taattgacta cgccaagcag aaccacatta acctcggtgc tattcaggtg
    21061 gtggtactgg acgaagccga tcgcatgtac gatctgggct ttattaaaga tatccgctgg
    21121 ctgttccgcc gtatgccgcc tgcaaaccag cgcctcaaca tgctgttctc cgccacgctt
    21181 tcgtaccggg tacgtgaact ggcgttcgag cagatgaaca atgccgaata tattgaagtg
    21241 gaaccggaac agaaaacggg ccaccgtatt aaagaagagc ttttctaccc ttctaacgaa
    21301 gaaaaaatgc gtttgctgca aacgctgatc gaagaagagt ggccagacag agcgattatt
    21361 ttcgccaaca ccaaacaccg ttgtgaagag atctggggcc acctggcagc agatggtcat
    21421 cgtgtcggtt tattgacagg cgatgtcgcg cagaaaaaac gtctgcgtat tcttgatgaa
    21481 tttacccgtg gcgatctgga tattctggtt gccaccgacg ttgccgcgcg tggtttgcat
    21541 attccggcag tgacgcacgt ctttaactac gatttacccg atgactgtga agattacgtt
    21601 caccgtattg gtcgtacagg tcgcgcaggc gcaagcggtc actctatcag cctggcgtgt
    21661 gaagagtatg cattgaattt gcctgctatt gagacctata ttggtcactc aattccggta
    21721 agcaaataca atccggacgc attgatgacc gatctgccaa aaccgctgcg cctcacgcgc
    21781 ccacgtacag gcaatggtcc gcgtcgtact ggcgctccgc gtaatcgtcg tcgttcaggt
    21841 taaataaaat gtcatactca aaatcattca aactgtatca agatggcaag agaatgaatc
    21901 ccgatgagca tactgtagta agtgattcag gtgaaagaat gcagccaaca cagagacaga
    21961 ttgaaggatg aagagtatgg gttccacctc gtcgctgtat gcagccattg atctcggttc
    22021 gaatagtttt catatgctgg ttgtgcgcga ggtggctgga agcatccaga cgctgacgcg
    22081 aataaaacgc aaagtgcgtc tggctgctgg cctgaatagc gaaaatgccc tgtctaatga
    22141 agcaatggag cgcggttggc aatgtctgcg cctgtttgct gaacgtctgc aagatatccc
    22201 tccctcgcaa attcgcgttg tcgctacggc gacattacgt cttgccgtca atgcgggtga
    22261 ttttattgcc aaagcgcagg aaatcctcgg ttgtccggta caggtgatca gcggtgaaga
    22321 ggaagcacgt ctgatttatc agggcgttgc tcacacaact ggcggtgccg atcagcgcct
    22381 ggtggtggat ataggcggtg ccagtactga actggtaacc ggcacgggtg cacaaaccac
    22441 ctcgttgttc agcctgtcga tgggctgcgt cacctggctg gaacgctatt ttgccgatcg
    22501 taatctgggg caggaaaatt ttgatgctgc agaaaaagcg gcacgcgaag tgttacgtcc
    22561 ggttgccgat gaattacggt atcacggctg gaaagtgtgc gttggtgctt ccggcaccgt
    22621 gcaggcgtta caggaaatca tgatggcaca ggggatggat gaacgcatta ccctggaaaa
    22681 gttgcagcaa ttgaaacagc gagccattca ttgcggtcgg ctggaggaac tggagattga
    22741 cgggctgacg ctggaacgtg cgttagtgtt cccgagtggt ctggcgatcc tgatcgccat
    22801 ttttaccgaa ctgaatattc agtgtatgac cctggcgggc ggtgcgctgc gtgaaggcct
    22861 ggtctacggc atgttgcatc tggccgtcga gcaggatatt cgcagccgta cgctgcgtaa
    22921 tattcagcgc cgctttatga tcgatattga tcaggcgcag cgcgtagcca aagttgcggc
    22981 taacttcttc gatcaggtgg aaaaggaatg gcatcttgaa gcaataagcc gcgatttgct
    23041 catcagcgcc tgtcagcttc atgaaatcgg cctgagcgtt gacttcaaac aagcgccgca
    23101 acacgctgct tatctggtgc gtaatctgga tcttcccggt tttacccccg cacagaaaaa
    23161 attgctggcg acgctactgc tcaaccagac taatccggtc gatctctcat cgctgcatca
    23221 gcaaaatgcc gtaccgccgc gcgtcgcaga acaactctgc cgtttactcc gcctggccat
    23281 catttttgcc agccgtcgcc gtgacgatct cgtgccagag atgacattac aggctaacca
    23341 tgaactgttg accttgacgc ttccgcaagg ttggctaacc caacatccgc tgggtaaaga
    23401 gattattgct caggaaagcc agtggcagag ctatgtccac tggtcgctag aagtgcatta
    23461 atgagtaagt gccggatgcg atgctgacgc atcttctccg gccttgatta tttccctcgt
    23521 tttgccgcca tcatcgcttt cagattcgcc agatggcttt gccctttctg catccgttct
    23581 tcggcgctga ccactttgcg ctcctgttcc caaatcagat catcctgcgg cagctccagc
    23641 aaaaagcggc tcggctccgg gcgcaccagc tcgccgtact gacggcgttc tttacacagc
    23701 gtaaaggtca attccttctg ggcgcgggta atgccgacat aggccagccg ccgctcctca
    23761 tcgatattat cttcatcgat gctgctctgg tgcggcaaaa acccttcttc cataccgacc
    23821 atgtagacat aaggaaactc cagccctttt gacgcgtgca gagtcatcag ttgcacctga
    23881 tccagctctt cttcactctc accacgctcc atcatgtcgc gcaaagtaaa gcgcgtcacc
    23941 acctgggtga gcgtcatcgg ctcatccagt tcgctgcctt ccagcatctc cgtcatccag
    24001 ctaaacagtt ggttgacgtt cttcatgcgc atttcggcag ctttcgggct gggcgatgtt
    24061 tcgtacagcc aggattcata atccatgccg tggatcagat cgcgcaccgc ggcaatcggc
    24121 tcccgctccg ccagacgctg aatttctgcc aaccagtgag tgaagcgggt caatgcttca
    24181 taaccacgtc cgctaagcgt ctgactcagg cccatatcaa agctggcggt aaacatgctt
    24241 ttattgcgcg tcatcgccca ctcacccagc tttttcagcg tagccgggcc aatctctcgc
    24301 ttcggcgtgt taacgatacg cagaaatgcg ctgtcatcgt ccgggttagt cagcacgcgc
    24361 agataagcca gcaagtcctt gatttcagga cgagagaaaa acgacgtacc accagaaatt
    24421 ttgtacggga tgcggttttg catcaggaat ttttcaaaca cccgcgactg atggttaccg
    24481 cgataaagaa tggcgtaatc tttgtactgc gttttattga cgaagtgatg ggcgatcagc
    24541 tcgccagtaa cgcgctcggc ttcatgttcc tcgttattcg cgcttaaaac ttttagctct
    24601 gtgccgtaac ccagttcgga gaacagacgc ttttcaaaga cgtgcggatt attggcgatc
    24661 aggatgttcg ccgctttcaa aatacgtccg gaagagcggt agttctgctc aagcttaatc
    24721 accttcagcg ccggaaaatc ctgactcagc agcaccaggt tttgtggacg tgcaccgcgc
    24781 caggagtaga tcgactggtc gtcatcgccc accacggtaa agcgcgcgcg gctgcccacc
    24841 agcagtttca ccagttcata ctggctggtg ttggtgtcct gatactcatc caccagcagg
    24901 tagcgaattt tgttctgcca gcgctcgcgg acttcttcat tgcgttgcag cagcaacgtc
    24961 ggcaataaaa tcagatcatc gaagtcgaga acgttacagg ctttcaggtg tgcatcatac
    25021 agcccataac aatgggcaaa aatacggtcc cgctcgccaa tcgcacttgc tgccgcctgg
    25081 gacggtgttt tgagatcatt cttccagtta gagatggtcg aaatcagttg ttgcaggaga
    25141 actttgtcat cttcaatcag cccctcggtc aactctttaa gcaaagcaag ctgatcggta
    25201 tcgtcaaaca acgagaagtt cgctttcatc ccaagcgccg catactcgcg tttgatgata
    25261 tccaacccca gcgtgtgaaa agtggagatc atcagcccgc gcgcctcttt gcgacccagc
    25321 gtctgcccga cacgctcttt catctcgcgc gccgccttat tggtaaaggt caccgccgcg
    25381 atatgtcgcg cctgataacc gcaaccgcgg atcagatggg cgattttatt ggtgataaca
    25441 cgagttttac cggaacccgc gcccgccagc accaggcagg ggccggtaac gaattcgaca
    25501 gcttgttgtt ggccggggtt tagacgcata ggtgtattgc tcaatcttcg aacgggggga
    25561 ggattgtagc agaatcgcat ttgaatgtga ccgcgtgtaa gccgctaacc ggttggctgc
    25621 ggatgtttaa atcagagagg gaagaccgaa accggagtta atcgtgaatc cattagactt
    25681 agaaaatatc gggtcgtaac gttgtgttat tactttttca gagtttacta aggagaggtt
    25741 tactcgtggc gataaatttc agccctaagg ttggtgaaat actggaatgc aactttggta
    25801 actatcctgt tagccagaat ggacagttca gcaccacgta ttacaatggc cgcattcctc
    25861 ctgaaatgat aaaaaacagg ttagttgtcg tgctcaacgg aaaaattaat ggcaacgcat
    25921 gtatcgtcgt tccattatca accactcgcg atcatgacaa gttaaatcgt ggaatgcatg
    25981 ttgaaatagc cagtaatgtt atcaatgacc tgcaattctt tgatcagcag attcgttggg
    26041 ccaaagccga cctggtacaa caagtcagtc gaaaccgatt aaacagagca aggacttaca
    26101 gagggtatct taatcaatgt ttgccacatg agttggttgc agacatacag agggcggtca
    26161 tcaagtcaat caatgccata tcgctcataa attgacaata aaatcaccat ccccgataat
    26221 gactctgtag cccatagagg ccctaagttt tctccccttg agggacctgc gaagcccgga
    26281 ttttccgggc ttttgccata tatgtaccag cccctccctg actgacaatt acgttagcat
    26341 ctgcggatca tgctaaaatc gccgcctgac aattattcac tcaaggcacg atcatggcaa
    26401 aaacagcagc agcactgcat atccttgtaa aagaagagaa actggctctg gatcttctcg
    26461 agcagattaa gaacggtgcc gatttcggca agctggcgaa gaaacactcc atttgcccat
    26521 caggcaaacg cggcggtgat ttaggtgaat tccgccaggg tcagatggtt ccggcgttcg
    26581 ataaagtagt tttctcttgt ccggtactgg agccgactgg cccgctgcat acccagttcg
    26641 gttaccacat cattaaggtg ctttaccgta actaatagca aggccttctc caggagaagg
    26701 ccttgaactc tgaatcgcta ttaacccgca acagcaatac gtttcatatc tgtcatatag
    26761 ccgcgcagtt tcttacctac ctgctcaatc gcatggctgc gaatcgcttc gttcacatca
    26821 cgcagttgcc cgttatctac cgcgccttcc ggaatagctt tacccaggtc gcccggttgc
    26881 agctctgcca taaacggttt cagcagcggc acacaagcgt aagagaacag atagttaccg
    26941 tactcggcgg tatcagagat aaccacgttc atttcgtaca gacgcttacg ggcgatggtg
    27001 ttggcaatca gcggcagttc gtgcagtgat tcatagtaag cagattcttc gatgatgccg
    27061 gaatcaacca tggtttcgaa cgccagttca acgcccgctt tcaccatcgc gatcatcagt
    27121 acgcctttat cgaagtactc ctgctcgccg attttgcctt catactgcgg cgcggtttca
    27181 aacgcggttt tgccggtctc ttcacgccag gtcagcagtt tcttatcatc gttggcccag
    27241 tccgccatca taccggaaga gaattcgccg gagatgatgt cgtccatatg tttctggaac
    27301 aggggtgcca tgatctcttt cagctgttca gaaagcgcat aagcacgcag tttcgccggg
    27361 ttagagagac ggtccatcat cagggtgatg ccgccctgtt tcagtgcttc ggtgatggtt
    27421 tcccaaccga actgaatcag tttttctgcg tatgctggat cggtaccttc ttccaccagc
    27481 ttgtcgaagc acagcagaga gccagcctgc aacataccgc acaggatggt ttgctcgccc
    27541 atcaggtcag atttcacttc cgcaacgaag gacgattcca gcacacccgc acggtgacca
    27601 ccggttgcag ccgcccaggc tttggcaatc gccatgcctt cgcctttcgg atcgttttcc
    27661 gggtgaacgg caatcagcgt cggtacgccg aacccacgtt tgtactcttc acgcacttcg
    27721 gtgcctgggc atttcggcgc aaccatcact acggtgatat ctttacggat ctgctcgccc
    27781 acttcgacga tgttgaaacc gtgcgagtag cccagcgccg cgccgtcttt catcagtggc
    27841 tgtacggtgc gcactacatc agagtgctgc ttgtccggcg tcaggttaat caccagatcc
    27901 gcctgtggga tcagttcttc gtaagtaccc actttaaaac cattttcggt cgctttacgc
    27961 caggacgcgc gcttctcggc aatcgcttct ttacgcagag cgtaggagat atcgagacca
    28021 gaatcacgca tgttcaggcc ctggttcaga ccctgtgcgc cacagccgac gatgactact
    28081 tttttaccct gaaggtagct cgcgccatcg gcgaattcat cgcggcccat aaagcgacat
    28141 ttgcccagct gtgccagctg ctggcgcaga ttcagtgtat tgaagtagtt agccatggtg
    28201 attcctcgtg atgttgtgct tcttattgtt cggttcgcgt ttgcgagatt gaattcacta
    28261 tatgacagga aatttattgc ggaaattgat atattcacaa cgtcacattg caatttttgc
    28321 aacgtcaaca tcgagggctg tccctgtgga tttacgcgat ctgaaaacct tcctgcatct
    28381 ggcggaaagc cgccattttg gccgcagcgc gcgggcgatg cacgttagcc catccacgct
    28441 ctcacggcag attcagcgcc tggaagaaga tctcggtcag ccgctgtttg tgcgcgataa
    28501 ccgcacggtg acgctgactg aagcgggcga agagctgcgc gttttcgccc agcaaacgct
    28561 gttgcagtat cagcagttgc gccacaccat cgatcagcaa gggccgtcgc tctctggcga
    28621 attacatatc ttctgctcgg tgaccgctgc ctacagccat ctgccgccga ttctggatcg
    28681 cttccgcgcg gaacacccgt cggtggagat taaacttact actggtgatg cggcagatgc
    28741 gatggaaaag gtggtcactg gtgaagcgga tctggcgatt gcgggtaaac cggaaacctt
    28801 gcccggcgca gtggcgtttt cgatgctgga gaatctggca gtagtgctga ttgcccccgc
    28861 gctgccctgc ccggtgcgta atcaggtgtc ggtagagaag ccggactggt caacggtgcc
    28921 gtttattatg gccgatcagg ggccggtacg ccgccgcatt gaactgtggt ttcgacgcaa
    28981 taaaatcagt aacccgatga tttacgccac ggttggcggg catgaagcga tggtatcgat
    29041 ggtggcactc ggctgtggcg tggcattgtt gccggaagtg gtgctggaaa acagccccga
    29101 accggtacgt aaccgcgtga tgattttaga gcgcagcgat gagaaaacgc cgtttgagct
    29161 gggcgtgtgt gcgcagaaaa agcggctaca tgagccgcta attgaggcat tctggaagat
    29221 tttgccgaac cacaaatgac gttgtcgcgc gggtaggcct gataagcgaa gcgctatcag
    29281 gcatttttcc ctaacccgcc aaaaagaacc tgaacgccgg gttattggtt tcgtcgtggc
    29341 aatcgtagcc cagctcattc agccgggttt cgaaatccgg ttcatggtcg ccaagttcga
    29401 acgccgccag tacgcgcccg tagtcggtgc catggctgcg atagtggaac aaagaaatgt
    29461 tccagtacgt acccagcgtg ttgaggaagc gcagcagcgc gcccggtgat tccgggaatt
    29521 cgaagctgta gaggcgttcc tgcaacggat gcgatggacg tccgccgacc atatagcgca
    29581 cgtgtagctt cgccatttcg tcgtcggaga gatcaaccac gctgtagccg ccgtcgttga
    29641 gcatctgcaa aatttctttg cgctcttcga ggccgcggct caggcgcaca ccgacaaaga
    29701 tgcaggcgtt tttggcatcg gcaaaacggt agttgaactc ggtgaccgaa cgcccgccaa
    29761 gcagttggca gaatttgagg aagctgcctt tttcttccgg aatggtcacc gccaacaacg
    29821 cttcacgctg ttcgcccagt tcgcagcgtt ctgagacgta gcgcaggccg tggaagttca
    29881 cgttggcacc ggaaagaata tgcgccagcc gttcgccgcg aatgttgtgc agggcgatat
    29941 attttttcat tcccgccagc gccagcgcgc cagagggttc cgccaccgcg cgcacatctt
    30001 cgaataaatc cttcatcgcc gcacagatcg catcgctatc gacggtgatg atgtcgtcga
    30061 gatactcctg gcataaacgg aaggtttcgt caccgatgcg ttttaccgct acgccttcag
    30121 caaatagccc tacgcgcggc agatcaaccg gatgacccgc atccagcgct gctttcaggc
    30181 aggcggagtc ttccgcttct acggcgatca ctttgatttg cggcatcagt tgtttgatca
    30241 gcaccgccac gccagcagcc agaccgccgc cgccgactgg cacaaatacg cggtcgagat
    30301 gggcgtcctg ctggagcagt tccagcgcca gcgtgccttg cccggcaatc accatcggat
    30361 ggtcgaacgg cggcacccag gtgaacccct gctgctgtga cagttcgatc gctttggctt
    30421 tcgcttcatc aaagttcgcg ccgtggagca gcacttcgcc gccgaagccg cgcaccgcgt
    30481 cgactttgat gtcggcggtg gcggttggca taacgatcag ggccttcacg cctaaccgcg
    30541 cagaagaaaa cgcgacgccc tgcgcgtggt tacccgcaga agcagtgatc acgccgtgcg
    30601 ctttctgttc ttccgtcagg cccgccatca tggcgtatgc gccgcgcagc ttaaagctgt
    30661 gcactggctg gcgatcttcg cgcttcacca gaatgacgtt atcaagacgc gacgacagtt
    30721 tttccatttt ttgtagcggc gtaacctgcg ccgcctcgta aaccggcgcg cgcagcactg
    30781 ctcttaaata ttcggcacct tccggagcac cggacagggg ttgcgagtca gccattatta
    30841 accccccagt ttcgatttat cgcgcaccgc gcctttgtcg gcgctggttg ccaggctggc
    30901 ataagcacgc agggcaaagg agacctgacg ttcacgattt ttcggcgtcc aggctttgtc
    30961 acctcgagcg tcctgcgctt cacgacgcgc cgccagttcg gcatcgctta cctgtaactg
    31021 aatgccacgg ttcgggatgt cgatagcgat caggtcacca tcttcaatca ggccaatgct
    31081 gccgccgctt gccgcttccg gtgagacgtg gccgatggaa agaccagagg tgccaccaga
    31141 gaaacgaccg tcggtgatca gcgcacaggc tttgccgaga cccattgatt tcaggaagct
    31201 ggttgggtag agcatttcct gcatccccgg accgcctttc gggccttcat agcgaattac
    31261 taccacatct ccggcgacaa ctttaccgcc gagaatcgct tctaccgcat cgtcctggct
    31321 ttcgtacact ttcgccgggc cggtgaattt gaggatgctg tcatcgacgc ctgccgtttt
    31381 cacgatgcag ccgttttccg caaagttacc gtagagcacc gccaggccgc cgtctttgct
    31441 gtaggcgtgt tccagcgagc ggatacagcc attggcgcga tcgtcgtcca gcgtatccca
    31501 acggcaatct tgcgagaatg cctgtgtggt acgaatgcct gcaggacctg cgcggaacat
    31561 attttttacc gcgtcatcct gggtcagcat aacgtcgtat tgttccagcg tttgcggcaa
    31621 cgtcaggcca agtacgtttt tcacatcacg gttcagtaac cccgcgcgat ccagttcgcc
    31681 gagaataccg ataacaccac cagcacggtg aacatcttcc atatggtatt tctgggtgct
    31741 cggcgcaact ttacacagct gtggaacctt gcgggaaagc ttatcgatat cactcatggt
    31801 gaagtcgatt tccgcttcct gcgccgccgc cagcaggtga agtacggtgt tagtcgatcc
    31861 acccatcgcg atatccagcg tcatggcgtt ttcaaacgcc gccttactgg cgatattacg
    31921 cggcagtgca ctttcgtcgt tttgctcgta ataacgtttg gtcaattcaa caatgcgttt
    31981 accagcatta aggaacagct gcttacggtc ggcgtgggtt gccagcagcg agccgttgcc
    32041 cggctgcgac aggcccagcg cttcggtcag gcagttcatt gagttagcgg taaacatccc
    32101 ggagcaggaa ccgcaggtcg gacacgcgga acgttcaacc tgatcgctct gggagtcaga
    32161 tactttcggg tctgcgccct ggatcatcgc atcaaccaga tcgagcttga tgatctgatc
    32221 ggaaagtttg gttttcccgg cctccatcgg gccgccggaa acaaagatca ccggaatatt
    32281 caggcgcagg gaagccatca gcatccccgg ggtgattttg tcgcagttag agatgcagac
    32341 catggcgtcg gcgcagtggg cgttgaccat atactcaacg gaatcagcga tcagttcgcg
    32401 agatggcagt gaataaagca tccccccgtg gcccatggca atcccatcat ccaccgcaat
    32461 ggtgttgaac tctttggcaa cgccgccagc cgcttcaatt tgttcggcga ccagtttacc
    32521 gagatcgcgc agatggacgt gacccggtac aaattgggtg aacgagttca caaccgcgat
    32581 aatcggcttg ccaaaatcgg catcggtcat tccggtggcg cgccacagcg cacgagcacc
    32641 cgccatatta cgaccatgag tggtggtggc ggaacggtac ttaggcatac tttatttact
    32701 cccagtgtct gtctcgtaaa tgggacggtg cgtgccgtcc cattttttgt atttattgat
    32761 taacttgatc taaccagccc catttatctt cggtttcgcc agtgaagagg ccgaagaagg
    32821 cttgctgaat gcgtttggta accggaccgc aacggccttc accaacctga ataccatcta
    32881 cgctgcgcac tggcgtgatt tctgccgcag taccggacat aaacacttca tccgccaggt
    32941 acagtgattc gcgcgacaga acctgctcac gcacttcaat tcccagctct ttcgccagtt
    33001 tgatgatggc atcacgggta atacccggca gcgcggagga ggtgaacggt ggggtgaaca
    33061 gcacgccgtc tttcacttca aacaggtttt cgcctgcacc ttcagagatg tagccattca
    33121 catccagcgc gataccttcc tgataaccgt ggcggcgcgc ttcgctaccc accagcaggg
    33181 aagagaggta gttaccaccg gcttttgccg ccgtcgggat ggtgtttggt gctgcgcggt
    33241 tccaggagga aaccatcgca tcgatcccct gctccagcgc ttctgcgccc agatacgctc
    33301 cccacgggaa agcagcgata atcacgtcgg ttgagtatcc cgctggcggg tttacgccca
    33361 tgccaacatc accaacgaag atcagcggac ggatataggc gctggtgaga ttgtttttgc
    33421 ggatcacgtc acgacaagct tccatcagct catcaatgct ctgcgaaacc gggaagcgat
    33481 agattttggc ggagtcatgc agacgctgca tatgctcacg atggcggaat acaaccggtc
    33541 ctttgtgcga gtcgtagcaa cggatgcctt caaaaaccga agtgccatag tgcagcgcgt
    33601 gcgacatcac atgcaccttc gcgtcttccc agcgaaccat ctccccattg aaccaaatgt
    33661 aatcagcttt cttcgtggtc atttttatat tccttttgcg ctcaggcgcg gatttgttgt
    33721 gatgtggttg tgctctggca gatggcaacg tgtgcgacgt ccaccagttt atttaactga
    33781 ctaaacagta agtcgaccga ccgtgggctg gcaacggtca attcgatatt tatattttgt
    33841 gcatcgctgg cggcagccat attcattgag cagacgtgga aaccacgatg acgcaccacg
    33901 cgtaaaacac gttctaaggt ttccggattg aagcgagccg atacattgac ctgatgttgc
    33961 atcatgataa tttctccaac atttctgaat tactggcgcc aggcggcacc agcggccaga
    34021 cgttctcaag ttcgtcgatt gagacatgaa gcaggtatgg cccatcactg ttcagcatgg
    34081 tgtcgagtgc cgcttcaacc tggtctttac gggtgatgtg ttggccaggg atgccgaagg
    34141 cgctggctaa catgaggaaa tcggggttat cagtaagggt ggtttcgctg tatcgttcct
    34201 gaaaaaacag ttgctgccat tgtcgaacca tccctaaccg ttggttatcg agtaagacga
    34261 ttttcaacgg taactgcttg cgttttacgg tgcccagctc ttgcacattc atcatgaaag
    34321 agccgtcacc ggagatacag acaacggtat cgttcggtcg cgcgacttgt gcgccaaccg
    34381 ccgccggtaa accaaaaccc atggtaccta aaccgctgga ggtgatgaaa ttttccgggc
    34441 gagtgtgggc gatgtgctgc gcagcccaca tctggtgctg ccccacatct gtggtcacga
    34501 cgcaatccgc aggtttacga tccgacagtt gttttaacaa caacggcgcg tagatagcgt
    34561 caccgggatg gtcgtaacgc caggaatgtt catcacgcag ctgcgcgcag tgttgctgcc
    34621 agtcattgat atttaacggc tgctgtaatg ctggtaacag agcatttaaa tcaccttgta
    34681 atgccacatg tgcctgacgc agcttgttca tttctgcctg gtcgatatcc atatggataa
    34741 cactggcgtg tggcgcgaag gtgttcagtt tgccggtcac ccggtcatca aaacgtgcgc
    34801 ccacggcgat cagcaggtca cactcctgca ccgcgaagtt tgccgctttg gtgccgtgca
    34861 tccccagcat gcccagatag tacggataat ctgcttctac tgcgcccagc cctttcagcg
    34921 tacaggtggc aggcattttt gtggcagcga gaaattcacg caaagccgga actgcctgcg
    34981 ccatacccac gccaccgcca acgtacagca tcggtttttg cgcttttgcc agcatctggc
    35041 gcgcttgctc aacttcggca tgtgggaaag tcacttcgtt ttcaacggtg gtgaaccacg
    35101 gttccaggtc accgctggct aactggatat cttttgggat atcgaccaga accggaccag
    35161 gacgacctga gcaggcaacg tcgaatgctt cagccatgat gcgcggcaac tcttccagcg
    35221 actgcaccag aaagctgtgc ttggtacagg ctaacgacaa tcccaggaca tccacttcct
    35281 gaaatgcgtc agtgccgata aacggtgcgg acacttgacc ggtgatggca acaacaggga
    35341 tggaatctaa cagtgcgtcc gcaagcccgg ttatcaggtt ggttgcgccc ggaccagacg
    35401 tggcgataca tacgccagtt ttgccggtag cacgagcata accgatagcc gccattgccg
    35461 caccctgctc atgtcggcat agcaagtgct ccacgccgcc gtcatacaat gcatcgtaaa
    35521 ccggcataat tgcgccaccc ggataaccga aaacggtgtt cacaccctgt gcccgcaacg
    35581 catgtaccac ccactgtgcg ccattcatag ttagttcccc gtcctgaatc ttgagaaaca
    35641 gaattttgtg ctgttattca ttgtctgctc ctcggttatg tttttaaggt caaaaaaacc
    35701 cccggacctt tcggtgcggg ggtcttagtt cgttaaggct tgatctctaa gcctttcctc
    35761 gtccaagtgc agccccgcac ggtgggataa taatcaccac cacgctaatc acgaccaggc
    35821 taatcactcg tagaagggct gtcattttgt cttttcttgc atcttgttcg aaggaatgcc
    35881 taaagagtta ccataggttt tgtaaatagt acaagatatt ttttggccga tttttatgat
    35941 gcgtttaata atttcaatat aaattgttgt tttttaaaaa taaaatagtg agtgaaaaaa
    36001 attcaatttc agtatgaatg ttgttccctt cctcgtagtt catcctttgt ccgctgcatt
    36061 tttgcgagca tcattccacc gccagaacaa ctcaacttca cttgcacaaa taaacaggaa
    36121 tcagccacta aaattcacga attagcgggc tacagcagcg atatcttatg cacataatgg
    36181 tgactcaagg agggcttatg tcactgtcaa ttgttcatac ccgcgcagcc ctgggagtaa
    36241 atgcgccccc gatcactgtt gaggtacata tcagtaaagg tctacccggc ttaacgatgg
    36301 tgggcttacc agaaacaacg gtaaaagaag ctcgcgatcg cgtgcgcagc gccattatca
    36361 atagcggata tgaatatccg gcgaaaaaaa tcaccatcaa cctggctcca gctgatctgc
    36421 caaaagaagg gggacgatat gatttaccta tcgccattgc gttgctggcg gcctcagaac
    36481 agcttacagc caataagtta gatgaatatg aattagtcgg agaactggcg cttacaggcg
    36541 ctctgcgtgg cgttcccggc gcaatctcca gtgcaactga agctattaag tcgggcagaa
    36601 aaattatcgt cgcgaaagat aacgaagatg aagtggggct aattaacggt gaaggatgcc
    36661 tgatagccga tcatctgcaa gctgtctgtg cgtttctgga aggtaagcac gctctcgaac
    36721 gcccgaaacc aactgatgca gtatcccggg cgctacaaca tgatctcagt gatgttatcg
    36781 gtcaggaaca aggaaagcga ggactggaaa ttaccgctgc tggcgggcac aaccttttac
    36841 tgattgggcc gccgggaaca ggtaaaacaa tgctcgccag ccgtattaat ggcctgttgc
    36901 cagatttaag caatgaagag gcactggaga gtgctgcgat attaagtctg gtaaatgctg
    36961 aatcagtaca aaaacaatgg cggcagcgcc cgttccgctc acctcatcac agtgcatcgt
    37021 taactgcgat ggtaggcggt ggcgcaattc cagggcccgg tgaaatttcg ctggcgcata
    37081 acggcgtgct ttttcttgat gagctacctg aatttgaacg gcgtacactg gatgccttgc
    37141 gagagccgat tgaatccggg cagatccatc tttcacgcac acgagcaaaa ataacctatc
    37201 cagcccgttt ccagcttgtt gcggcgatga atcccagccc taccggacat tatcagggaa
    37261 accataaccg ctgcacgcca gaacagacat tacgttatct caaccggctc tcggggccct
    37321 ttctcgaccg cttcgatctc tcactggaga tcccattacc accccccggc attttgagta
    37381 aaacggtagt gccgggagaa agcagcgcca ccgttaaaca acgcgtaatg gccgccagag
    37441 agcgccaatt taagcggcag aataaactga atgcctggct ggatagtccg gaaatacgcc
    37501 aattctgcaa acttgagagc gaagatgaga tgtggttgga aggaacactg atccatctgg
    37561 ggttatcgat tcgtgcctgg cagcggttat tgaaagttgc acgaaccatt gctgatattg
    37621 atcagtctga cattatcaca cgtcagcatt tgcaggaggc agttagctat cgagcgattg
    37681 accgtttgct catccatctg cagaaactac tgacataaaa aaagggcatt tcgccctttt
    37741 tattaatcgt cagaatcggt gtagtcttca gcaccttcaa cctgcggttt accgccggaa
    37801 agggtgtgaa aacgttttgg acgcttaata cgcgtcatat acttggacca cacgcgttct
    37861 gcttctgtca ctggctcacg ttcgccacgg catactgcta cgaagagttt ctcttcctcg
    37921 gtaaccggct cgcgtttgcc aagatccaac tcattgaagg cataaccatg acgctcaagc
    37981 agttgtgcct ctttgatggt gaaatcacca tgacgagaga atccacgtgg ataatgttta
    38041 ttgtcgaaat atcgattagt cgtcgtaaag ctttccgcca tcctgcacgc tcctaattct
    38101 ttgaccgagc tagttatggc gcggagtatt agttacgctt gacagagtgt aaaacaaaac
    38161 atttaaatca taacgacaaa taattttgcg gagagcactg tggatacgga attgttaaaa
    38221 actttcctgg aagttagccg aacgcgtcac tttggtcgag cggctgaatc gctctatctg
    38281 acccagtcag cagtgagctt tcgaatcaga caactggaaa atcaactggg tgtgaacctt
    38341 ttcacccgcc acagaaacaa tatccgttta accgctgccg gtgaaaaact actgccttat
    38401 gcagaaacgc tcatgagcac ctggcaggcc gcccgtaagg aggtggcgca tacctcacga
    38461 cataacgagt tttctatcgg tgccagcgcc tcgttgtggg aatgtatgct taatcagtgg
    38521 ctgggacgct tgtatcaaaa tcaggatgcc catacaggct tacagttcga agcgcgaatt
    38581 gcccaacggc agtctctggt aaaacagctg catgaacgcc agcttgatct tcttattacc
    38641 actgaagcgc ccaaaatgga cgaatttagt agtcagttgc tgggatattt cactttagcg
    38701 ctttatacca gtgccccttc aaaactaaag ggagatctta attatctgcg acttgagtgg
    38761 gggccagatt ttcaacagca tgaggcaggt ttgatcggtg ctgacgaagt gcccattctg
    38821 acaaccagtt ctgctgaact ggcacagcaa cagattgcga tgcttaatgg ttgcacctgg
    38881 ctacccgtca gctgggcgcg taaaaaaggc ggcctgcata ccgttgtcga tagcacaaca
    38941 ctttcacggc cgctttatgc catatggctg caaaatagcg ataaaaatgc gttgattcgc
    39001 gatcttttga aaattaacgt gctggatgaa gtgtattaat atgaatggct ggcaaggatg
    39061 ccggtagaag gatttacttc ggagagggtt atttcagata aaaaaaatcc ttagctttcg
    39121 ctaaggatga tttctggcag gggcggagag actcgaactc ccaacacccg gttttggaga
    39181 ccggtgctct accaattgaa ctacgcccct aattag
//
LOCUS       DAPHKZ010000033        38563 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.033, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000033 DAPHKZ010000000
VERSION     DAPHKZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38563
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.033"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(202..1143)
                     /gene="fabY"
                     /locus_tag="RH288_001788"
                     /gene_synonym="yiiD"
     CDS             complement(202..1143)
                     /gene="fabY"
                     /locus_tag="RH288_001788"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HDV4030844.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAH
                     HQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQM
                     QVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     gene            complement(1188..1625)
                     /gene="dtd"
                     /locus_tag="RH288_001789"
     CDS             complement(1188..1625)
                     /gene="dtd"
                     /locus_tag="RH288_001789"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDV4030845.1"
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANR
                     LCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRA
                     EALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     gene            complement(1622..2494)
                     /locus_tag="RH288_001790"
     CDS             complement(1622..2494)
                     /locus_tag="RH288_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HDV4030846.1"
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEDDEP"
     gene            complement(2488..3087)
                     /gene="yihX"
                     /locus_tag="RH288_001791"
     CDS             complement(2488..3087)
                     /gene="yihX"
                     /locus_tag="RH288_001791"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HDV4030847.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRIPLATLKKSFHMGEAF
                     HQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSD
                     TVFFDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC"
     gene            complement(3186..3971)
                     /locus_tag="RH288_001792"
     CDS             complement(3186..3971)
                     /locus_tag="RH288_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418320.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV4030848.1"
                     /translation="MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQTEEKKAIAEAVADYIPDGSTIFI
                     TIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
                     AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHA
                     SAAVEIGNVAQVTALFTDELPPAALKSRLQDSQIEIILPQEDA"
     gene            complement(4005..4901)
                     /gene="yihV"
                     /locus_tag="RH288_001793"
     CDS             complement(4005..4901)
                     /gene="yihV"
                     /locus_tag="RH288_001793"
                     /EC_number="2.7.1.184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructose kinase"
                     /protein_id="HDV4030849.1"
                     /translation="MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATA
                     AVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVNTRYTKRYNQAKSSQSAIMVDAT
                     GERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
                     GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGC
                     DWLENGGRQHQPAFKVDVVDTTGAGDVFHGALAVALATGGDLAESVRFASGVAALKCT
                     RPGGRAGIPDCDQTRSFLSLFV"
     gene            5069..5965
                     /gene="yihU"
                     /locus_tag="RH288_001794"
     CDS             5069..5965
                     /gene="yihU"
                     /locus_tag="RH288_001794"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HDV4030850.1"
                     /translation="MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKG
                     ATPAANPAQAAKDAEFIITMLPNGDLVRSVLFGENGVCESLSTDALVIDMSTIHPLQT
                     DKLIADMQAKGFSMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELIN
                     AGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTT
                     SWPNKVLSGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYSQARAAGRGR
                     QDWSAILEQVRVSAGMTAKVKM"
     gene            5989..6867
                     /gene="yihT"
                     /locus_tag="RH288_001795"
     CDS             5989..6867
                     /gene="yihT"
                     /locus_tag="RH288_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructosephosphate aldolase"
                     /protein_id="HDV4030851.1"
                     /translation="MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSV
                     LTDFKVNAAKTLSPYASAILVDQQFCYRQVVEQNAIAKSCAMIVAADEFIPGNGIPVD
                     SVVIDRKINPLQIKQDGGKALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEP
                     VVRPPRRGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGPQQELLCASQRLNDHI
                     NMPWVILSSGVDEKLFPRAVRVAMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPK
                     LQQLGDIVDEMMAKRR"
     gene            6883..8124
                     /gene="yihS"
                     /locus_tag="RH288_001796"
     CDS             6883..8124
                     /gene="yihS"
                     /locus_tag="RH288_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovose isomerase"
                     /protein_id="HDV4030852.1"
                     /translation="MKWFNTLSHNRWLEQETDRIFDFGKNSVVPTGFGWLGNKGQIKE
                     EMGTHLWITARMLHVYSVAAAMGRPGAYSLVDHGIKAMNGALRDKKYGGWYACVNDEG
                     VVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEIIEKYFWSEEEQMCLESWDE
                     AFSKTEEYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRVASVIIHDVARNNHYRVNE
                     HFDTQWNPLPDYNKDNPAHRFRAFGGTPGHWIEWGRLMLHIHAALEARCEQPPAWLLE
                     DAKGLFNATVRDAWAPDGADGIVYTVDWEGKPVVRERVRWPIVEAMGTAYALYTVTGD
                     RQYETWYQTWWDYCIKYLMDYENGSWWQELDADNKVTTKVWDGKQDIYHLLHCLVIPR
                     IPLAPGLAPAVAAGLLDINAK"
     gene            8193..9095
                     /locus_tag="RH288_001797"
     CDS             8193..9095
                     /locus_tag="RH288_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001417111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose-1-epimerase"
                     /protein_id="HDV4030853.1"
                     /translation="MQITNMHCSGQTVSLAAGDYHATIVTVGAGLAELTFQGCHLVIP
                     HKPEEMPLAHLGKVLIPWPNRIANGCYRYQGQEYQLPINEHGSKAAIHGLLAWRDWQI
                     SELTATSVTLTAFLPPSYGYPFMLASQVVYSLNARTGLSVEIASQNIGTVTAPYGVGI
                     HPYLTCNLTSVDEYLFQLPANQVYAVDEHANPTTLHHVDELDLNFTQAKKIAATKIDH
                     TFKTANDLWEITITHPQQALSVSLCSDQPWVQIYSGEKLQRQGLAVEPMSCPPNAFNS
                     GLDLLLLEPGKTHRLFFNIYGQHN"
     gene            9156..10031
                     /locus_tag="RH288_001798"
     CDS             9156..10031
                     /locus_tag="RH288_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDV4030854.1"
                     /translation="MDFFTLFSPDGVMLETNVVCIVIALMFLYTFVGICAGFGGGLTT
                     MPLVTLMLPVKMATPLSVIVGTATALYATWLSRKETDWRSAMVLIIFSFLGIPVGLYA
                     LSYLPDHFMKVGLGGFLILYSFYSMFIPRLPIYDRNWIAAPIGAVAGALGAAFSTNGP
                     PMVIYGMLRNLGPAAFRGTLNAFFTANNIAVIGGLATSGILTVSIFKLVLFCIPTMIL
                     GSLVGQYVHKRISVKVFRVMVFLLLIASGSMLIKGALGIPAAAALLPPFTLLVILQLA
                     FGKKVAAIRRAEESK"
     gene            10140..12176
                     /gene="yihQ"
                     /locus_tag="RH288_001799"
     CDS             10140..12176
                     /gene="yihQ"
                     /locus_tag="RH288_001799"
                     /EC_number="3.2.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovosidase"
                     /protein_id="HDV4030855.1"
                     /translation="MDTPRPQLPDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSG
                     IADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGR
                     LLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
                     TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALW
                     EDKATLRFECADTYISLLEKLTALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMR
                     NAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRIKQWNKEGVQFLAYI
                     NPYVASDKDLCEEAAKRGYLAKDVAGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKK
                     NMIELGCGGWMADFGEYLPTDTYLHNGISAEIMHNAWPALWAKCNYEALEETGKLGEI
                     LFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGY
                     TTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFARMTTVFT
                     TLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYSLKYQYLLGRDILVAPVHEEGRS
                     DWTLYLPEDNWVHAWTGETFHGGEITVEAPIGKPPVFYRADSEWAALFASLKNI"
     gene            12222..13607
                     /locus_tag="RH288_001800"
     CDS             12222..13607
                     /locus_tag="RH288_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4030856.1"
                     /translation="MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFY
                     TDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTL
                     LAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
                     RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYV
                     ETQPTNPAQKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDP
                     ILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVNF
                     VAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGF
                     FPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRI
                     VEEIEARKRTA"
     gene            13647..15050
                     /locus_tag="RH288_001801"
     CDS             13647..15050
                     /locus_tag="RH288_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4030857.1"
                     /translation="MSDHNPLTLKLNLWEKIAYGMGDVGSNLMLSIGTLYLLKFYTDE
                     LGMPAYYGGIIFLVAKFFTAFTDMLTGFLLDSRKNIGPKGKFRPFILYAAVPAALIAT
                     LQFIATTFSLPVKTTIATALFMMFGLSYSLMNCSYGAMIPAITKNPNERAQLAAYRQG
                     GATIGLLICTVAFIPLQSLFSDSTVGYACAALMFSIGGFIFMMLCYRGVKEHYVDTAP
                     TGHKASILKSFCAIFRNPPLLVLCIANLCTLAAFNIKLAIQVYYTQYVLNDINLLSWM
                     GFFSMGCILVGVLLVPLTVKCFGKKQVYLAGMVLWAVGDILNYFWGSNSFTFVMFSCV
                     AFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFFRKISAALAGFLPGIML
                     TQIGYVPNIAQSDATLQGLRQLIFIWPCALAIIAALTMGFFYTLNEKRFALIIEEINQ
                     RKNKEIETEEKTASVTL"
     gene            15117..15809
                     /gene="ompL"
                     /locus_tag="RH288_001802"
     CDS             15117..15809
                     /gene="ompL"
                     /locus_tag="RH288_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpL"
                     /protein_id="HDV4030858.1"
                     /translation="MKNINAIILLSSLTSASVFAGAYVENREAYNLASDQGEVMLRVG
                     YNFDMGAGIMLTNTYTFQREDELKHGYNEIEGWYPLFKPTDKLTIQPGGLINDKSIGS
                     GGAVYLDVNYKFVPWFNLTVRNRYNHNNYSSTDLSGELDNNDTYEIGTYWNFKITDKF
                     SYTFEPHYFIRVNDFNSSNGKDHHWEITNTFRYRINEHWLPYFELRWLDRNVEPYHRE
                     QNQIRIGTKYFF"
     gene            complement(15900..17165)
                     /locus_tag="RH288_001803"
     CDS             complement(15900..17165)
                     /locus_tag="RH288_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4030859.1"
                     /translation="MLTKKKWTLFSLLTLCGGTIYKLPSLKDAFYIPMQEYFHLTNGQ
                     IGNAMSVNSFVTTVGFFLSIYFADKLPRRYTMSFSLIATGLLGVYLTTMPGYWGILFV
                     WALFGVTCDMMNWPVLLKSVSRLGNSEQQGRLFGFFETGRGIVDTVVAFSALAVFTWF
                     GSGLLGFKAGIWFYSLIVIAVGIIIFFVLNDKEEAPSVEVKKEDGASQHTSMTSVLKD
                     KTIWLIAFNVFFVYAVYCGLTFFIPFLKNIYLLPVALVGAYGIINQYCLKMIGGPIGG
                     MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAV
                     FFAPIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDLNPGIIGYKIVFGIMA
                     CFAFCGAVVSVMLVKRISQRKKEMLAAEA"
     gene            complement(17267..18247)
                     /locus_tag="RH288_001804"
     CDS             complement(17267..18247)
                     /locus_tag="RH288_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDV4030860.1"
                     /translation="MMTINNARKILQRVDTLPLYLHAYAFHLNMRLERVLPADLLDIA
                     SENNLRGVKIHVLDGERFSLGNMDDKELSAFGDKARRLNLDIHIETSASDKASIDEAV
                     AIALKTGASSVRFYPRYEGNLRDVLSIIANDIAYVRETYQDCGLTFTIEQHEDLKSHE
                     LVSLVKESEMESLSLLFDFANMINANEHPIDALKTMAPHITQVHIKDALIVKEQGGLG
                     HKACISGQGDMPFKALLTHLICLGDDEPQVTAYGLEEEVDYYAPAFRFEDEDDNPWIP
                     YRQMSETPLPENHLLDARLRKEKEDAINQINHVRNVLQQIKQEANHLLNH"
     gene            complement(18255..18965)
                     /locus_tag="RH288_001805"
     CDS             complement(18255..18965)
                     /locus_tag="RH288_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HDV4030861.1"
                     /translation="MAENQSTVENAKEKLDRWLKDGITTPGGKLPSERELGELLGIKR
                     MTLRQALLNLEAESKIFRKDRKGWFVTQPRFNYSPELSASFQRAAIEQGREPSWGFTE
                     KNRTSDIPETLAPLIAVTPSTELYRITGWGALEGHKVFYHETYINPEVAPGFIEQLEN
                     HSFSAVWEKCYQKETVVKKLIFKPVRMPGDISKYLGGSAGMPAILIEKHRADQQGNIV
                     QIDIEYWRFEAVDLIINL"
     gene            complement(19182..21005)
                     /gene="typA"
                     /locus_tag="RH288_001806"
     CDS             complement(19182..21005)
                     /gene="typA"
                     /locus_tag="RH288_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HDV4030862.1"
                     /translation="MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAI
                     TGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD"
     gene            21378..22787
                     /gene="glnA"
                     /locus_tag="RH288_001807"
     CDS             21378..22787
                     /gene="glnA"
                     /locus_tag="RH288_001807"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HDV4030863.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
                     SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLS
                     KNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            23073..24122
                     /gene="glnL"
                     /locus_tag="RH288_001808"
     CDS             23073..24122
                     /gene="glnL"
                     /locus_tag="RH288_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HDV4030864.1"
                     /translation="MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDG
                     MILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRVTESIHKVAERVVTLVSMELPDNV
                     RLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            24134..25543
                     /gene="glnG"
                     /locus_tag="RH288_001809"
     CDS             24134..25543
                     /gene="glnG"
                     /locus_tag="RH288_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HDV4030865.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVAE
                     STSQMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAR
                     LLGWGRNTLTRKLKELGME"
     gene            25655..25765
                     /locus_tag="RH288_001810"
     CDS             25655..25765
                     /locus_tag="RH288_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HDV4030866.1"
                     /translation="MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS"
     gene            complement(25994..27367)
                     /gene="hemN"
                     /locus_tag="RH288_001811"
     CDS             complement(25994..27367)
                     /gene="hemN"
                     /locus_tag="RH288_001811"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDV4030867.1"
                     /translation="MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAG
                     RHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAF
                     LTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     CYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQW
                     DLHFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARM
                     QQFSRVI"
     gene            complement(27556..28062)
                     /gene="yihI"
                     /locus_tag="RH288_001812"
     CDS             complement(27556..28062)
                     /gene="yihI"
                     /locus_tag="RH288_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HDV4030868.1"
                     /translation="MKPSSPSRSKGHAKARRKTREELNQEARDRKRQKKRRGHAPGSR
                     AAGGNTTSGSKGQNVPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELLE
                     TDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQED
                     MMRLLRGN"
     gene            28644..29276
                     /locus_tag="RH288_001813"
     CDS             28644..29276
                     /locus_tag="RH288_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDV4030869.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE"
     gene            complement(29658..32444)
                     /gene="polA"
                     /locus_tag="RH288_001814"
     CDS             complement(29658..32444)
                     /gene="polA"
                     /locus_tag="RH288_001814"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDV4030870.1"
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
                     GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEVTATVISYDNYVTIL
                     DEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDA
                     PDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAEL
                     EKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHRDDVDAVAKQIHQLMENCTRLDVPL
                     LVEVGSGENWDQAH"
     gene            32808..33740
                     /locus_tag="RH288_001815"
     CDS             32808..33740
                     /locus_tag="RH288_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HDV4030871.1"
                     /translation="MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVK
                     LLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVHGLEGLSKKNWYLLICN
                     HRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWALDMPFMKRYSRAYLLRH
                     PERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIA
                     MALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYIN
                     DKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQNK"
     gene            complement(33781..35211)
                     /locus_tag="RH288_001816"
     CDS             complement(33781..35211)
                     /locus_tag="RH288_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HDV4030872.1"
                     /translation="MIRKSATGVIVALAVIWGGGTWYTGTQIQPGVEKFIKDFNDAKK
                     KGEHAYDMTLSYQNFDKGFFNSRFQMQMTFDNGAPDLNIKPGQKVVFDVDVEHGPLPI
                     TMLMHGNVIPALAAAKVNLVNNELTQPLFIAAKNKSPVEATLRFAFGGSFSTTLDVAP
                     AEYGKFSFGEGQFTFNGDGSSLSNLDIEGKVEDIVLQLSPMNKVTAKSFTIDSLARLE
                     EKKFPVGESESKFNQINIINHGEDVAQIDAFVAKTRLDRVKDKDYINVNLTYELDKLT
                     KGNQQLGSGEWSLIAESIDPSAVRQFIIQYNIAMQKQLAAHPELANDEVALQEVNAAL
                     FKEYLPLLQQSEPAIKQPVRWKNALGELNANLDISIADPAKSSSSTNKDIKSLNFDVK
                     LPLNVATETAKQLNLSEGMDAEKAQKQADKQISGMMTLGQMFQLITIDNNTASLQLRY
                     TPGKVVFNGQEMSEEEFMSRAGRFVH"
     gene            complement(35366..35992)
                     /gene="dsbA"
                     /locus_tag="RH288_001817"
     CDS             complement(35366..35992)
                     /gene="dsbA"
                     /locus_tag="RH288_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HDV4030873.1"
                     /translation="MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEF
                     FSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDVGKDLTQAWAVAMALG
                     VEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
                     AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYANTVKYLSEKK"
     gene            complement(36009..36995)
                     /gene="srkA"
                     /locus_tag="RH288_001818"
     CDS             complement(36009..36995)
                     /gene="srkA"
                     /locus_tag="RH288_001818"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response kinase SrkA"
                     /protein_id="HDV4030874.1"
                     /translation="MNNSAFTFQTLHPDTIMDALFEQGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFY
                     FAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
                     EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDL
                     DDARNGPAIQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVY
                     YLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY"
     gene            complement(37072..37341)
                     /locus_tag="RH288_001819"
     CDS             complement(37072..37341)
                     /locus_tag="RH288_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HDV4030875.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELAD
                     LTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE"
     gene            37411..37995
                     /gene="mobA"
                     /locus_tag="RH288_001820"
     CDS             37411..37995
                     /gene="mobA"
                     /locus_tag="RH288_001820"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HDV4030876.1"
                     /translation="MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALM
                     TQLSHVVVNANRHQEIYQAGGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDT
                     PYIPPDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMAF
                     MRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR"
     gene            37977..38504
                     /gene="mobB"
                     /locus_tag="RH288_001821"
     CDS             37977..38504
                     /gene="mobB"
                     /locus_tag="RH288_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418293.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDV4030877.1"
                     /translation="MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHT
                     HHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLQFLASRMDTSKL
                     DLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVE
                     GLADFVVEWMQKQNG"
BASE COUNT         9430 a         9780 c         9438 g         9915 t
ORIGIN      
        1 atgaattaag cattatctgc gataattgcc actcagttct acaaataata tttaaatgct
       61 cctgaacagt gatgtagcaa gacacgtatg gagccaacga agaataaaaa tttatagagt
      121 tcttatttaa tataaccgaa atagccaagg actaatataa atgacctgaa tgagagaggc
      181 agcaccgccc ctctccatca gctactcttc ttcgttcccg ccctcttcat acgggccaaa
      241 tggcttcgcg ggcagaacga tatacgtgcc ttcaaacact gcacccggcg tctcgtcgcc
      301 aaagatttcg acctgcatct gcacccgtgc ttttcgtccg cgcgccagac ggtcgagatc
      361 gccgcttaag gcaccgaggt cggctaccgc atgaggttta ccgctaatcg gcttgctgta
      421 gcggatatgc gcatccgcaa gaataatcgt tccgccgagg tggcgttcac gcagcatcag
      481 ccagataagt ccccaaccgg tgagcgtcgc cagtgagaat aaactcccgg caaacagcgt
      541 atggtgcgga ttctgattgc cggtttctgg catggtagtg ataaattttt gcccggtata
      601 ttgctgaatg cgcacgccca ttttttcact aagcgggata tgttcgtacc acgcctgttg
      661 cagctgcgcg caccagtcgc cgcgatgcaa aatatcatcc agagtggcga cgggcttaat
      721 catcaaaaaa tggcgaatcg gcgtggtggt tggcgtggtg atttctccct gattaacaaa
      781 ccccagcttg gcgaaaaact ccaccgcgtc ttcacgggcg ctacaggtca cgcgcttaac
      841 gccttcctga cgcgccaccg actccagggt catcgccatc agcgttccta accctttgtc
      901 ctgcacgtcc gggtgaacgg ccataaagcg aatggacgct tcattgtcgg cattaatata
      961 cagtcggcct accgccacca gattaccctg ctcgtcgacg accatctggt gatgcgccat
     1021 cgcatcccac gcgtcgcgtt ccgaaccttt tggttgatgc aggggcttac gcaacatttc
     1081 ccagcgaaac tgatagtaac gctctaattc ttcttctgtt tgtggaaccc gaaggtgata
     1141 catagcgata ctctctcttg tttcccgtga caaccctgga agctggctca tacctgcaac
     1201 cagaatgtca cggggccatc attgaccagc gatacctgca tatccgcagc gaagcgtcct
     1261 gtttgcgtgt tcatctcttg ctgacggcag cgttcgacga aatagtcata taacgcctct
     1321 gcgcgatccg gtgatgcacc tttggagaaa cttgggcgca tcccccgttc ggtatctgcg
     1381 gcgagggtaa actgggaaac caccagcaca ctgccgcccg cctgttgcac gttgaggttc
     1441 atcttgcctt cggcatcgct aaagatgcgg tagccgagca cacgctcgca cagacggttt
     1501 gctttctgtt cgtcgtcatc cttttcgaca cccaataaca ccaaaagtcc cgcgccaatt
     1561 tcgcccgtca cttctccctc cacggtgacg ctggcacggg ttacgcgttg aattaatgca
     1621 atcatggttc gtcgtcttct tcttgttcag ctgcttgttt tagtttgcgg tattccccga
     1681 gagtgacagt aatttccgcg ccaagcaaga cgatacacca tgtccagtag acccaaacaa
     1741 agagaatggg gatcaccgcc aacacgccgt aaatgagctg atatgacgga aacatggtga
     1801 tataaagcgc gaaacctttc tttcctgctt cgaacaggag cgcggcgaca aacgcgccga
     1861 caatcgcgtc gcggttaggt acgcggatgg taggaacaat gctgtacagc aaccagaagg
     1921 agatccacga caacagcagc ggaaaaatac gcagcacgtt atcgatgaca gtattgagat
     1981 cgctcgccca gcgcagggag agcaaatagg aactgatcgc cagactggcc cctgccagca
     2041 gcggccccag cgttaaaatc atccagtaca cggcgaacga gtaaattttt ggtcgcgctc
     2101 gtttactgcg ccagatggta ttcaacgcgc tatcgatgga gtacatcagc aataacgcgg
     2161 tgacgatcag cccgcacgcc ccaacggcgg tcatcttgtt ggaattggca acaaattgtt
     2221 cgatataccg ctgaataaca tcgccagtag caggcagaaa gttggcaaaa ataaagtgac
     2281 gtaactgaat gctgacgtcg gaaaacatgg gaaaagcggc gaaaagcgca aaaacaacgg
     2341 caaccagcgg cactaatgag agcaacgaca cataggcaag gttacctgcc agggttgtca
     2401 tgttgtcctc atcaatgcgt tgccagagta gttttagcca ggcccatagt ggacgggtac
     2461 ggtgcctggc tttgtcctga atggttttta gcataacacc ttcgcgaaat agtccgggat
     2521 ggtggtttta tctttcacca gaatactggt aatgcccagc tgattagctc cttctatatt
     2581 atcggcgtta tcgtcgaaaa agaccgtatc gctgggtgaa aaaccttccg cctgcaaaac
     2641 atgctggtaa attcgtgctt caggtttgcg catccccaga tcttgcgaca gatagatatg
     2701 gtcagcagca tcacgaattt ccgggtattc ttccggccag aaggtggtat gcaggcggtt
     2761 ggtattggaa agcaccacca cgcgatgccc ctgctcacgc agtttatgca tgatggcgat
     2821 cacttccggg cgcagcgcaa caaacaccgc ctgccagccg tgagagaact gctcgtagct
     2881 tagcggtaga gccatctcat gacacagcgc ctctgcgaac gcttcgtcgc taatttcccc
     2941 acgctcatgc tgatgaaacg cctcccccat atgaaaactc ttcttaagcg tagccagcgg
     3001 aatacgcgtt aaatcgctcc aggctcccag cacacggtta aagtcgatat cgacaatcac
     3061 attacctaaa tcaaagatat agagcatttt tgcctccttt cgcgccacaa gaaattaact
     3121 gtagcgggaa aggatgggtt tggctatgtg gcaaggtatg aagccaggtc aacggtcaca
     3181 aaaatctacg cgtcttcctg gggaagaatg atttcaattt ggctgtcttg taagcgtgat
     3241 tttagcgcag cgggcggcag ctcgtcggta aagagcgcgg tgacctgtgc cacgttacca
     3301 atttcaaccg ccgccgaagc atgatactta gtgtgatcgg cgaccagcag gatatttctc
     3361 gcgtgcgcca tcatcgtttt caccacgtta gcttcgttaa catcaaactc catcaacgcg
     3421 ccatcgctct cgattgcgcc tacgcttgtt accagataat cagcacgaaa atcggccaca
     3481 aaggacgccg ctgaagggcc aatgatcccg ctattatgag agcgcaacgt accgccgggc
     3541 accatcactt caaagcgcgg gttgtggtaa agaatatgcg ccacacgcag gctgttggtg
     3601 attatccgca aatgattatg gttaagtaac gcccgggcga catgctcaac ggtcgtacca
     3661 atggtgataa atattgttga accatcagga atatagtctg ccactgcttc ggcaatcgct
     3721 tttttttcct cggtttgcga aacctcacgc tgctcgaacg ccgtattaac gacgctggaa
     3781 gcccgacccg cgccaccgtg atggcgcgta atcaggcctt gctcgcttaa tttacgaata
     3841 tcccggcgca ccgtctgcgt ggagacatcc agcagatttg caagctcatc aatattcata
     3901 tacccacgct cggcgatcag catgaggagt tggtcgtgcc gcgggttacc ggttagttcg
     3961 gtaaggctca tgaaaattcc tcgaaaaacc atcaccctgg cattttatac aaaaagtgac
     4021 aaaaaagatc gggtttgatc acagtcaggg atcccggctc gtccaccggg acgcgtgcat
     4081 ttcaacgccg ctacaccgct ggcgaagcgg actgactccg ctaaatcccc acctgttgcc
     4141 agcgccaccg ccaatgcgcc gtgaaaaaca tcacccgcac ctgtggtatc taccacatca
     4201 actttgaagg ccggttgatg ttgacgcccg ccattttcca gccagtcaca gcctgcgctg
     4261 ccctgggtca catagacatg accatttgtg agcgtttgtg cctgttttag cgcactggcc
     4321 atctctttca cgcccgttaa gcgcgccaga cccggttctg aaaaggccgc atgatcgctt
     4381 aatgccacca gctcgctgat atcctgcggc gtaatatcac cgtccagaac ggtcatcacg
     4441 cccgcctgcc gggccagagt gaaggctttt ttagcgccgt cgtgccagcg tacatctgcc
     4501 agcacaacat cccactgaga gaaatcaatt tcctccaacc actctgcgtc aggcagcagg
     4561 tccgggctgg ggtagttaat gattatccgc tcgcctgtgg catccaccat gatggcggat
     4621 tgcgatgatt tcgcctggtt ataccgtttg gtgtaacggg tgttaacgcc ccaggattcc
     4681 agctctgcca gcaggctgtt gcccgtgtcg tcatcaccta cgcgaccaat aaaatcaacc
     4741 tgcgccccca gccttgccgc cgcaaccgct gccgtcgccg ctggcccgcc accaacttcc
     4801 gtataatttc tcgccacgta tttaccgctc tccgtcggta acccttccac gtaatagatg
     4861 cgatccatca cggttatacc tacacaagca acacgaatca tggtcattcc ttaaacattt
     4921 tgggatgcgt tcattttaat ttcaccaatt gtttaaaaag tgacggctgt caattttttg
     4981 actataaatt acaaatacga tcaaaaacag acaatcaaag cgtgtcataa atgacaaaaa
     5041 gtgacatcgc tgtattcagg agaaggttat ggcagcaatc gcgtttatcg gtttaggaca
     5101 aatgggttcg ccaatggcga gcaatttatt gcagcaaggg caccaacttc gcgtctttga
     5161 tgtgaatgcc gaggctgtgc ggcatctggt agacaaaggc gcgactcccg ccgccaaccc
     5221 ggcgcaggcc gctaaagatg ccgaatttat cattaccatg ttgccgaatg gcgatctggt
     5281 gcgcagcgtg ttgttcggtg aaaacggcgt ttgcgaaagc ttatctaccg atgcgctggt
     5341 cattgatatg tcgaccatcc atccgctgca aaccgataaa ttgattgccg atatgcaagc
     5401 caaaggcttc agcatgatgg atgttccggt aggccgtact tctgcaaatg ccattaccgg
     5461 tactctgtta ctgctggctg gcggcaccgc tgaacaagtt gaacgtgcca cgccgatcct
     5521 gatggcgatg ggcagtgagt tgattaacgc tggcggtccg ggcatgggga tccgcgttaa
     5581 gctcatcaac aactatatga gcatcgcgct caatgcgctt tcggcagaag ctgccgtttt
     5641 gtgcgaagct ctgaatcttc ccttcgatgt tgccgtcaaa gtgatgagcg gtaccgccgc
     5701 cggtaaaggc cacttcacca cttcctggcc aaacaaagtc ctcagcggag atctttctcc
     5761 cgccttcatg atcgatcttg cccataagga tcttggcatc gcccttgatg tcgccaacca
     5821 gctgcatgtg ccaatgccgc tgggggccgc ctcacgggag gtttatagcc aggcgcgcgc
     5881 agcgggtcgc ggtcgccagg actggtccgc cattctggaa caggtccgtg tcagtgccgg
     5941 gatgactgcc aaagtaaaaa tgtaacgact ggataaagga ataaatgaat gaataagtac
     6001 accatcaacg acattacgcg cgcatcgggc ggttttgcca tgctggcggt cgatcagcgc
     6061 gaagccatgc gcatgatgtt tgccgcggct ggggcacccg ctccggtagc cgatagcgtt
     6121 ttaactgatt tcaaagttaa cgcggcgaag accctctcgc cttatgcctc ggcgattctg
     6181 gtagatcaac aattctgtta ccgccaggtg gttgagcaaa acgcgattgc caaaagttgc
     6241 gccatgattg tcgccgccga tgagttcatt cctggcaacg gtattccggt agatagcgtg
     6301 gtcattgacc gcaaaatcaa tccgctacag atcaaacaag acggtggcaa agccttaaaa
     6361 ctgctggtgc tgtggcgtag tgatgaagat gcgcagcaac gcctggatat ggtgaaagag
     6421 tttaacgaac tgtgccactc acacggcctg gtaagcatta ttgagccagt cgtccgccca
     6481 ccacgtcgtg gcgataaatt cgatcgcgaa caagcgatca tcgatgctgc caaagagctg
     6541 ggcgacagtg gcgctgacct ctacaaagtt gaaatgccgc tttacggtaa aggtccgcaa
     6601 caagagcttc tctgtgcttc acaacgtctg aatgaccata tcaatatgcc gtgggtgatc
     6661 ctctcttccg gtgtcgacga aaaactgttc ccgcgtgccg tacgcgtggc aatgacagcg
     6721 ggtgcatcgg gcttcctggc tggtcgtgcc gtctgggcat cggtcgtcgg tttaccagac
     6781 aacgagctga tgctgcgtga cgtttgtgca ccgaaattac aacaactggg cgatatcgtc
     6841 gacgaaatga tggctaaacg ccgttaagat ggggatacaa aaatgaaatg gtttaacact
     6901 ttaagtcaca accgttggct ggaacaggaa accgatcgca tctttgattt tggtaaaaat
     6961 tccgtagtac cgactggatt tggctggtta ggcaataaag ggcaaatcaa agaagagatg
     7021 ggcacccatc tgtggatcac agctcggatg ttgcacgttt attccgttgc tgcggcgatg
     7081 ggtcgacctg gcgcttactc gttggttgat cacggtatta aagccatgaa cggcgcactg
     7141 cgcgataaaa aatatggcgg ctggtatgcc tgtgtgaatg acgagggcgt ggtggatgcc
     7201 tccaaacagg gctatcaaca tttctttgct ctgctgggtg ctgccagcgc cgtcactacc
     7261 ggtcatccgg aagcgcgcaa gctgctcgat tacaccattg aaattatcga gaaatacttc
     7321 tggagcgaag aagagcagat gtgcctggag tcctgggacg aagccttcag caaaaccgaa
     7381 gagtaccgcg gcggcaatgc caatatgcac gcagtggaag ctttcttaat tgtttatgac
     7441 gtaacgcatg acaaaaaatg gctggatcgc gcgattcgcg tggcttccgt gattatccac
     7501 gacgtcgcaa gaaataatca ttatcgcgtt aacgaacact tcgataccca gtggaatccg
     7561 ctgccggatt acaacaaaga taacccggcg caccgcttcc gcgcgttcgg aggtacacca
     7621 ggccactgga tcgaatgggg ccgtttaatg ctgcacatcc acgcggccct ggaagcccgt
     7681 tgcgaacaac cgccagcatg gctgctagaa gatgccaaag gtctgtttaa cgccaccgtg
     7741 cgtgatgcct gggcacccga tggtgcggac gggattgttt ataccgttga ctgggaagga
     7801 aaaccggtgg tccgcgaacg tgtgcgttgg cctatcgtcg aagcgatggg tacggcctac
     7861 gcgctctaca ccgtcaccgg cgatcgccag tatgaaacct ggtatcagac atggtgggac
     7921 tactgcatta agtacctgat ggactatgaa aatggttcct ggtggcagga gctggatgcg
     7981 gacaataaag tcaccacgaa agtctgggac ggtaaacagg atatttatca cctgctgcat
     8041 tgcctggtga tcccgcgtat cccgttagcg ccaggcctgg ctccggcagt tgcggcgggt
     8101 ctgctggata ttaacgcgaa atagctgact aaaaaaaaac gacatatcag gctgcacgcc
     8161 gggtatgtcg ttattcaata aaggtacctc gtatgcaaat caccaacatg cattgcagtg
     8221 gacagaccgt ttcacttgcc gcgggggatt atcacgcgac cattgtgacc gtcggtgcag
     8281 gtctggctga attaaccttt cagggctgtc atttagttat tccacataaa cccgaagaga
     8341 tgccgctggc acatctgggc aaagtcctta ttccgtggcc gaaccggatc gccaacggct
     8401 gttatcgcta tcaggggcag gaatatcagt tacccattaa tgaacatggt tcaaaagccg
     8461 ctattcatgg gctgctcgcc tggcgtgact ggcaaatcag cgaattaacc gccaccagcg
     8521 ttaccctgac agcttttctg ccacccagtt acggctatcc gtttatgctg gcttcgcagg
     8581 ttgtttattc gctcaatgca cgcacgggtc tttccgttga gatcgcaagt cagaatattg
     8641 gtactgtgac cgcaccctat ggtgtgggta ttcatcctta tttaacctgc aacttaacat
     8701 ctgttgatga atatctgttc cagcttccgg caaaccaggt ttatgccgtc gatgagcacg
     8761 ctaatccgac aacgcttcac cacgttgatg agctggattt aaatttcacg caggcgaaaa
     8821 aaatagccgc gacaaaaatc gaccacacct ttaaaaccgc taatgatctg tgggaaataa
     8881 ccattaccca tccacaacag gcgctttcgg taagcctttg ttccgatcaa ccctgggtgc
     8941 agatttatag cggcgaaaaa ttacagcgtc agggactggc agttgaacct atgagttgcc
     9001 cacctaacgc ctttaattca ggtctcgact tattattact ggaaccaggg aaaacgcacc
     9061 gcctgttttt taatatttac gggcagcaca attaatttta ttaagaaaag aacgagatca
     9121 ttgtttaggg ttgtatttac acaacaggaa atatcatgga cttttttacg ttattttcac
     9181 cggatggggt catgctggaa acaaacgtgg tatgtatcgt tatcgcgtta atgtttcttt
     9241 atacctttgt ggggatatgc gcgggatttg gcggtggttt aaccaccatg ccgctcgtca
     9301 cgttaatgct ccccgtaaaa atggcaactc cgctctcggt gattgtcggc accgcgaccg
     9361 ccttgtacgc cacctggctg tcacgtaaag aaacggattg gcgatcggca atggtactga
     9421 ttattttctc gtttctggga atacccgtcg gtttatatgc gctgtcatat ttacccgacc
     9481 attttatgaa agtgggctta ggcggattcc ttatcctgta ctccttttac agtatgttta
     9541 ttccacgcct gccgatttat gaccgcaact ggatcgccgc acctatcggc gctgtggcag
     9601 gagcgttagg ggcagcgttt tcaaccaacg gaccgccgat ggttatctac ggtatgctgc
     9661 gtaacttagg cccggcggca tttcgtggca ctctgaacgc tttcttcacc gcaaacaaca
     9721 tcgcggtgat cggcgggctg gcgaccagcg gaattttgac tgtttctatc tttaaactgg
     9781 tgctgttttg tattcccacc atgatcctcg gttcactggt tggacaatat gtgcataaac
     9841 gcatttcagt caaagtgttc cgtgtgatgg tctttttgtt gctgattgcc tccggttcta
     9901 tgttgataaa aggcgcgctg ggaattcccg ctgctgccgc gcttctgcct ccttttacct
     9961 tgttagttat actgcaactg gcatttggta aaaaagtggc ggcaatccgc cgggctgaag
    10021 aaagtaaata atcacttatg cgggttttaa tttataccag caccacattc tttaattaat
    10081 gaaacctgta acaacaggat ggcatgaaat attagcttta tactctatgg agattattta
    10141 tggatacgcc acgcccacaa ttaccagatt ttcagtttca tcagaataac gacagtttta
    10201 ccctacattt tcaacagcgt cttattttaa cccatagcaa agataatcct tgtttatgga
    10261 ttggttcagg tattgcggat atcgatatgt tccgcggcaa tttcagcatt aaagataaac
    10321 tacaggagaa aattgcgctt accgacgcca tcgtcagcca gtcgccggat ggttggttaa
    10381 tccatttcag ccgtggttct gacattagcg ccacgctgaa tatctctgcc gacgatcagg
    10441 gccgtttatt gctggaacta caaaacgaca accttaacca caaccgtatc tggctgcgcc
    10501 ttgccgctca accagaggac catatctacg gctgcggcga acagttttcc tacttcgatc
    10561 tgcgtggcaa accgttcccg ctatggacca gtgaacaagg cgttggtcgc aataaacaaa
    10621 cctatgtcac ctggcaggcc gactgcaaag aaaatgcggg cggcgactat tactggactt
    10681 tcttcccaca gcctacgttt gtcagcacgc agaagtatta ctgccatgtt gataacagtt
    10741 gctatatgaa cttcgacttt agtgccccgg aataccatga actggcgctg tgggaagaca
    10801 aagcaacgct gcgttttgaa tgtgctgaca catacatctc cctgctggaa aaattaaccg
    10861 ccctgctggg acgccagcca gaactgcccg actggattta tgacggagta acgctcggca
    10921 ttcagggcgg gacggaagtg tgccagaaga aactggacac catgcgtaac gcgggcgtga
    10981 aggtcaacgg catctgggcg caggactggt ccggtattcg tatgacctct tttggcaaac
    11041 gcgtgatgtg gaactggaag tggaacagcg aaaactaccc gcaactggat tcgcgtatca
    11101 agcagtggaa caaagagggc gtgcagttcc ttgcctatat caacccgtat gttgccagtg
    11161 ataaagatct ctgcgaagag gcggcaaagc gcggttatct ggcaaaagat gtcgccggtg
    11221 gcgactatct ggtggagttt ggcgagttct acggcggcgt tgtcgatctc accaatccgg
    11281 aagcctacgc ctggttcaag gaagttatca aaaagaacat gattgaactc ggctgcggcg
    11341 gctggatggc tgacttcggc gagtatctgc ccaccgacac gtacctgcat aacggcatca
    11401 gcgcggaaat tatgcataac gcctggcccg cgctgtgggc gaaatgtaac tacgaagccc
    11461 ttgaagaaac gggcaagctc ggcgagatcc tcttctttat gcgcgccggt tctaccggta
    11521 gccagaaata ctccaccatg atgtgggcgg gtgaccagaa cgtggactgg agtctggacg
    11581 atggcctggc gtcggttgtc ccggcggcgc tatctctggc aatgaccgga catggcctgc
    11641 atcacagcga cattggcggt tataccaccc tgtttgagat gaagcgcagc aaagagctgc
    11701 tgctgcgctg gtgcgatttc agcgccttca cgccgatgat gcgcacccac gaaggtaacc
    11761 gtcctggcga caactggcag tttgacggcg acgcggaaac catcgcccat ttcgcccgta
    11821 tgaccaccgt cttcaccacc ctgaaacctt acctgaaaga ggccgtcgcg ctgaatgcga
    11881 agtccggcct gccggttatg cgcccgctgt tcctgcatta cgaagacgac gcgcagacct
    11941 attccctgaa atatcagtac ctgttaggtc gcgacattct ggttgctccg gtacacgaag
    12001 aaggtcgcag cgactggacg ctctatctgc cagaggataa ctgggtccac gcctggaccg
    12061 gagaaacctt ccacggtgga gaaataactg ttgaagcgcc catcggcaag ccgccggtct
    12121 tttatcgcgc cgacagcgaa tgggctgcac tgttcgcctc gttaaaaaac atctaatcat
    12181 gcccgcccgt ggggaaactc acgggcaaat ggagaataac gatgagtcac atcacaacgg
    12241 aagatccggc aactttgcgc ctgcccttta aagagaaact ctcttacggt atcggcgatc
    12301 tggcctctaa catcctgctg gatattggta cgctttatct tttgaagttt tataccgacg
    12361 ttctggggct gcctggcacc tatggcggca ttatcttttt gatctcgaaa ttctttaccg
    12421 cctttaccga tatgggaacc ggcatcatgt tggattcccg acgcaagatc ggtccaaaag
    12481 gtaaattccg tccttttatt ctgtatgcgt cattcccggt taccttattg gcaatcgcta
    12541 actttatcgg cacaccgttc gatgtcaccg gtaaaacggt gatggccact attctgttta
    12601 tgctttacgg actgtttttc agcatgatga actgctccta cggcgcaatg gttcccgcca
    12661 ttaccaaaaa ccccaacgaa cgcgcctcgc tggcagcatg gcgtcagggc ggcgctacgc
    12721 tgggcctgct gctgtgcacg gtgggattcg tgccggttat gaatcttatc gagggtaatc
    12781 agcaacttgg ctatatcttc gccgccacgc tgttttcact gtttggcctg ctgtttatgt
    12841 ggatctgcta ttcgggcgtg aaagagcgtt atgtcgaaac ccaacctacc aatccggcgc
    12901 aaaagccagg cctgttgcaa tctttccgcg caattgccgg taaccgccca ctgttcattt
    12961 tgtgcattgc caacctctgt accttagggg cgtttaacgt caagctcgcc attcaggtct
    13021 attacaccca gtacgtgctt aacgatccca tcctgttgtc atatatggga tttttcagca
    13081 tgggctgtat tttcatcggc gtgttcctga tgcctggtgc agtcaggcgt tttggtaaga
    13141 agaaggtcta tattggcggt ctgctgatct gggtgctggg cgatctgctc aactatttct
    13201 tcggcggcgg ctcggtcaac tttgtggctt tctcctgcct ggcgttcttt ggttcggcgt
    13261 ttgttaacag cctgaactgg gcgctggttt ctgacaccgt cgagtacggc gagtggcgca
    13321 ccggtgtccg ttctgaaggg acggtctaca ccggcttcac cttctttcgc aaagtttctc
    13381 aggcgctggc aggtttcttc cccggctgga tgctgacgca aattggctat gtgccgaacg
    13441 tcgcacaggc tgaccacacc attgaagggt tgcgccagct gatcttcatc tacccaagcg
    13501 cactggcggt agtcaccatt gtagcgatgg gctgcttcta cagcctgaac gagaagatgt
    13561 atgtccgcat tgttgaagaa atagaagccc gtaaacgcac ggcgtaataa taaacgacgc
    13621 cctgcggggc gttataagga gtgattatgt ctgaccataa tccactgaca ttaaaactga
    13681 atctgtggga aaaaatcgcc tatggtatgg gcgacgttgg ttcgaattta atgcttagca
    13741 tcggtactct gtatctcctc aaattttata ccgatgaatt agggatgcca gcttactatg
    13801 gcgggattat ctttctggtg gcgaagtttt ttaccgcgtt taccgatatg ctcaccggat
    13861 ttttactcga ctcgcggaaa aatattgggc ctaaaggcaa atttcgtccc tttattttat
    13921 atgcagcggt tccggcggcg ttaattgcaa cgctccagtt tatcgccacc acttttagtt
    13981 tgccggttaa aacgacgatt gccacggcgc tgtttatgat gtttgggctt tcatacagtc
    14041 tgatgaactg ctcgtatggc gcgatgatcc cggcaattac caaaaacccg aatgagcgcg
    14101 cgcagctcgc ggcttaccgc cagggtggtg caaccatagg gctattgatt tgtaccgtgg
    14161 cgtttattcc gttgcagtcg cttttttctg actcaaccgt cggttatgcc tgtgcggcac
    14221 ttatgttctc cattggcggc tttattttta tgatgctgtg ctacagaggc gtcaaagagc
    14281 attatgtgga cacagcacca accggacata aagccagtat tctcaaatct ttttgcgcga
    14341 tatttcggaa tccgccattg ctggttttat gcattgctaa cttgtgtacc ctggcggcat
    14401 ttaatatcaa actggcgatt caggtctatt acacccagta tgtgctgaat gatattaatt
    14461 tattgtcgtg gatgggattc ttcagtatgg gatgcatcct cgtcggcgta ttactggtgc
    14521 cattaactgt aaaatgtttt ggtaaaaaac aggtttattt agctggcatg gtgctatggg
    14581 cggttggtga tatcctgaat tatttctggg gaagtaactc tttcactttc gtcatgttct
    14641 cttgtgtcgc cttttttggc acggcctttg taaacagcct gaactgggcg ctggtaccag
    14701 ataccgtaga ttacggtgaa tggaaaaccg gtattcgtgc cgaaggttct gtttataccg
    14761 gttatacctt ctttcgtaaa atttctgccg cacttgctgg cttcttgcca ggcattatgc
    14821 tgacgcaaat cggttatgtt cccaacatcg cgcaaagtga tgcgacatta cagggtttgc
    14881 gtcagctcat ttttatctgg ccttgtgcac tggcaattat tgctgcattg acgatgggat
    14941 tcttttacac actcaatgaa aaacggtttg cgttgattat tgaggaaatc aaccaacgca
    15001 aaaataaaga aattgagaca gaagaaaaaa cggcttccgt aacgttataa atgtcaatag
    15061 ccgctatttc catcctggtg ggtggcggcc tccctacgtt taaaaatgga cttattatga
    15121 aaaatattaa tgcaataatt ttattatctt ctctgacctc tgcctcagta ttcgctggcg
    15181 catacgtcga aaacagggag gcatataatc tcgcctccga tcagggcgag gttatgctac
    15241 gtgtgggtta taacttcgat atgggcgcgg gtattatgtt aaccaatacc tacacctttc
    15301 agcgagaaga tgaactaaaa catggatata acgaaatcga aggttggtat ccgttattta
    15361 aaccaaccga taaattaacc atccagcccg gtggcttaat taatgataag agtatcggtt
    15421 cgggtggtgc agtgtatctg gacgtcaact ataaatttgt accatggttt aatctgacag
    15481 tacgaaatcg ctataaccat aataactata gttcaacaga tttgagcggg gaactggata
    15541 ataatgacac ctatgaaatt ggtacctact ggaattttaa aatcaccgat aagttctcct
    15601 atacatttga gccacattat tttatacgcg taaatgactt taatagcagc aatggaaaag
    15661 atcatcactg ggaaatcact aacaccttcc gttatcgcat taatgaacac tggctgcctt
    15721 atttcgaatt acgctggtta gatcgtaatg tcgaaccgta ccaccgcgag caaaaccaga
    15781 ttcgtatcgg gacgaagtat ttcttctgat gtgaaactgc cggatgcggc gtaaacgcct
    15841 tatccggcct acggttgata cggttttcgt tggccggatt aagcacatcc ggccattaat
    15901 taagcttcag ccgccagcat ctctttctta cgttggctaa tacgcttaac cagcattacg
    15961 gaaaccaccg caccacagaa tgcgaagcag gccataatgc caaacacgat tttgtagcca
    16021 ataatccccg gatttaaatc cagaatgtag ccatacagac tgaagcagaa catcgccggg
    16081 gcgtaaccaa taaagctacc caacgccatc gccgcgcctg ttttattttc agcaattttt
    16141 gcttcgccga taggtgcaaa aaatacggct cgctgtgtaa agactatcgc gccaaagccc
    16201 agcgtacatg ccatccctaa atagaccggc atactttcgt gcggcagcat aatcaacagt
    16261 acgagcgcag cggtactgat gataaaggtg tagcatagat atttactcgg cgatttcagg
    16321 atcttatctg aaatcatgcc accaatcggt ccaccaatca ttttcagaca gtattggtta
    16381 atgatgccgt aagcccccac cagcgcaacg ggcaatagat agatgttttt caggaatgga
    16441 atgaagaatg tcaggccaca gtaaaccgcg taaacgaaga agacgttgaa agcgataagc
    16501 cagatagttt tgtctttcag caccgaggtc atactggtgt gttgcgatgc cccatcttct
    16561 tttttcacct caacggacgg tgcctcttct ttgtcattca ggacaaagaa aataataatg
    16621 cctacggcaa tcacaataag ggaatagaac cagatgcctg ctttaaaacc taataagcca
    16681 ctgccaaacc aggtaaatac tgccaacgca gaaaatgcca ccacggtatc gacaatgcca
    16741 cgccctgttt cgaagaagcc aaacaaccga ccttgttgtt cgctattgcc caatcgactt
    16801 accgacttga gcaagaccgg ccagttcatc atgtcgcaag taacgccaaa tagcgcccag
    16861 acaaagagga tgccccaata ccccggcatt gtcgtcaaat aaacacccag taatcctgtc
    16921 gcaatgagtg agaatgacat ggtgtatctg cgcggtagtt tatcggcaaa ataaatagac
    16981 agaaaaaagc ccactgtggt aacaaatgag tttaccgaca tggcattacc aatttgacca
    17041 ttggtcaaat ggaaatattc ctgcatcggg atataaaacg catctttcag cgacggtaat
    17101 ttataaattg taccgccaca cagtgttaat agactaaata acgtccattt ctttttcgtg
    17161 agcataacat cccctaagcg atttttaaaa tcactgtttt aaaggcaata agataccgac
    17221 cattcatata gaatggtttt attaactgcg tatgagttaa aacttattag tggttcagaa
    17281 gatggtttgc ctcttgtttg atttgttgta gtacgttacg cacatgattt atctgattaa
    17341 ttgcatcttc tttttcttta cgtaaccgcg catccagtaa atgattttct ggtaggggtg
    17401 tttcactcat ctggcgataa gggatccacg gattatcatc ttcgtcttca aagcggaacg
    17461 ccggcgcata gtaatcaacc tcttcttcca ggccatatgc cgtcacctgc ggctcatcat
    17521 caccaaggca gataaggtgc gttaataacg ctttgaacgg catatcaccc tgacctgaaa
    17581 tacaggcttt atgacccagg ccaccctgtt ctttaacgat caaggcatct ttaatatgga
    17641 cctgggtaat atgcggtgcc atcgttttta aggcgtcgat gggatgctca tttgcattga
    17701 tcatgttcgc aaaatcaaac agtaaggaaa gagactccat ctcactttct ttgaccagcg
    17761 acaccagctc atgacttttt aaatcttcat gctgctcaat cgtaaaagtc aggccgcagt
    17821 cctgatacgt ttcccgtaca taggcaatgt cgttagcgat aatcgataat acgtcgcgca
    17881 aattaccttc ataacgtgga taaaaacgta cggacgatgc cccagttttc aacgcgatgg
    17941 cgacggcttc gtcaatagat gccttatctg aggcgctggt ttcaatatga atatcaaggt
    18001 tcagacggcg ggctttatct ccaaaggcag agagttcttt atcgtccata ttaccaagag
    18061 aaaaacgctc gccatccaga acatggattt tgacgccacg tagattattt tcacttgcga
    18121 tatcaagtaa atcagcaggc aacactcttt ccagccgcat atttaaatga aaggcataag
    18181 catgtaaata aagaggaaga gtgtcgacac gttgtagaat ctttcttgcg ttatttattg
    18241 tcatcataaa acacctacag attaatgatg aggtctacgg cctcaaatcg ccaatattca
    18301 atatctatct ggacaatatt gccttgctgg tcggcgcgat gcttttcaat taagatcgct
    18361 ggcatacccg cagaaccgcc aagatacttg ctgatatcgc ccggcattct gacgggtttg
    18421 aaaatcaatt tttttactac cgtctctttt tggtagcact tttcccagac tgcagaaaat
    18481 gagtggtttt caagttgttc aataaaaccc ggagcaactt caggattaat atatgtttcg
    18541 tgatagaaaa ctttatgtcc ttccagcgcc ccccagccgg tgatgcgata gagttcagtt
    18601 gatggtgtca ctgcaatcag tggcgcgagc gtctcgggaa tatcgctggt acggtttttc
    18661 tcggtaaacc cccaggaagg ctctcgtcct tgctcaattg cggcccgctg aaagctcgct
    18721 gacagctccg gactgtaatt aaatcgcggc tgggtcacga accacccctt acgatcctta
    18781 cggaagattt tggattctgc ctcgaggttc aacaacgcct ggcgcagcgt catacgttta
    18841 atgcccagca gttctcccag ctctctttct gaagggagtt ttccacccgg cgtggtgatg
    18901 ccatctttca accaccgatc cagtttctct tttgcatttt ctacggtgga ttgattctcc
    18961 gccattgttt aatccttttg gtttaaacca gatgaagcat cttacgctta cgccaaaaaa
    19021 gaaagcaatt aacggtgtat gactttgcag ataattgtga caaagctctc tattgacgta
    19081 atcacagact tataagggag atactcgcat tggtgtgcgc tcacgacagg taaaaaaaaa
    19141 cctgccagcg atggcaggtt ttttataact aaaaaacgaa attaatcgtc tttcggtgcg
    19201 cggttagcgc gacgacgatc gttttccgtc aggtgacgtt tacgaatacg gatagaggtt
    19261 ggagtcactt ctaccagttc gtcatcatcg atgaactcca gagcttgttc cagagtcatg
    19321 cggataggcg gaaccagaac aacggcttcg tcagtaccgg aagcacgcat gttggtcagt
    19381 ttcttaccgg tcaggcagtt taccgtcagg tcgttagagc ggctatgaat accgataatc
    19441 tgaccttcgt aaacttctgc accgtgaccg aggaacagct taccgcgatc ctgcagaccg
    19501 aacagcgcga acgcgaccgc tttaccctga ccgttagaga tcagtacgcc gttctgacgc
    19561 tggcccactt cacccggacg tacgtcgtcg tagtggctga aggtggagta cagcagacca
    19621 gtaccggaag tcatggtcat gaactcagaa cggaagccaa tcagaccacg gcttgggatc
    19681 acgtagtcga gacgtacgcg gcctttaccg tctggattca tgtttttcag gtcgccttta
    19741 cgttcgccca gcgcctgcat cacagaaccc tgatgctgtt cttcaacgtc cagcgtcacg
    19801 ttttcatacg gctcttgttt acgaccgtcg atttcacgga agattacttt cggacgggat
    19861 accgccagtt cgaaaccttc acgacgcatg ttttcgatca gaacagacag gtgcagttcg
    19921 ccacgaccag aaacgcggaa cgcatcggcg tcttcggttt cttctacgcg cagcgcaacg
    19981 ttgtgtacca gttctttgtt cagacgatcc aggatctgac gagacgttac gaacttacct
    20041 tctttaccgc agaacggcga ggtgttaacg cagaagaaca tagaaacggt cggctcatca
    20101 acggagagtg ccggcagcgc ttcaacgttt tgcgtgtcgc aaacggtgtc agaaatgttc
    20161 agttcgccca ggcccgtgat cgccacgata tcgccagctt ccgccaggtc ggtttcgata
    20221 cgttccagac cgaggtggcc cagcacttta ccgactttcg cgttgcgggt tttgccttcg
    20281 ctatcgatga tagtgacctg ctggttcggc ttcactttac cgcgcttgat gcggccaatg
    20341 ccgataacgc caacatagct gttgtaatcg agctgagaaa tctgcatctg gaacggaccg
    20401 tcaaggtcaa cgtccggcgc aggaacgtgg tcaacaatcg cctggtacag cggggtcatg
    20461 tcttccgcca tatcttcgtg gtccagaccc gcgataccgt tcagcgcaga agcgtaaacg
    20521 atcgggaagt ccagctgctc gtcggtcgcg tcgaggttaa cgaacagatc gaatacctga
    20581 tccacaaccc aatcaggacg cgcgccaggg cggtcaactt tgttgataac aacaatcggc
    20641 ttcaggccgt aagcaaacgc ttttttggtt acgaagcgcg tttgcggcat cgggccgtca
    20701 aatgcgtcaa ccaccagcag cactgagtct accatggaca ttacacgttc aacttcacca
    20761 ccgaagtcgg cgtgccccgg ggtatcaacg atgttgatac ggtaatcatt ccatttgata
    20821 gcggtgtttt tcgcgaggat ggtaatccca cgctctttct ccaaatcgtt ggagtccatc
    20881 acgcgctctt gggtttcggc acgagagtcg aacgtaccgg attgttggag cagcttgtct
    20941 accagggtag ttttaccatg gtctacgtgc gcgatgatgg cgatattacg caatttttcg
    21001 atcacaactt tgcctcaggc attagaaata gcgcgttatt gtacacggat taatcgcact
    21061 acaaaacagg atcacaaaca tcctccgcaa acaagtattg cagagtccct ttgtgatcgc
    21121 tttcacggag cataaaaagg gttatccaaa ggtcattgca ccaacatggt gcttaatgtt
    21181 tccattgaag cactatattg gtgcaacatt cacatcgtgg tgcagccctt ttgcacgatg
    21241 gtgcgcatga taacgccttt taggggcaat ttaaaagttg gcacagattt cgctttatct
    21301 tttttacggc gacacggcca aaataattgc agatttcgtt accacgacga ccatgaccaa
    21361 tccaggagag ttaaagtatg tccgctgaac acgtactgac gatgctgaac gagcacgaag
    21421 tgaagtttgt tgatttgcgc ttcaccgata ctaaaggtaa agaacagcac gtcactatcc
    21481 ctgctcatca ggtgaatgct gaattcttcg aagaaggcaa aatgtttgac ggctcctcga
    21541 ttggcggctg gaaaggcatt aacgagtccg acatggtgct gatgccagac gcatccaccg
    21601 cagtgattga cccgttcttc gccgactcca ccctgattat ccgttgcgac atccttgaac
    21661 ctggcaccct gcaaggctat gaccgtgacc cgcgctccat tgcgaagcgc gccgaagatt
    21721 acctgcgttc cactggcatt gccgacaccg tactgttcgg gccagaacct gaattcttcc
    21781 tgttcgatga catccgtttc ggatcatcta tctccggttc tcacgttgct atcgacgata
    21841 tcgaaggcgc atggaactcc tccacccaat atgaaggtgg taacaaaggt caccgtccgg
    21901 cagtgaaagg cggttacttc ccggttccgc cggtagactc tgctcaggat attcgttctg
    21961 aaatgtgtct ggtgatggaa cagatgggcc tggtggttga agcccatcac cacgaagtag
    22021 cgactgctgg tcagaacgaa gtggctaccc gcttcaatac catgaccaaa aaagctgacg
    22081 aaattcagat ctacaaatat gttgtgcaca acgtagcgca ccgcttcggt aaaaccgcga
    22141 cctttatgcc aaaaccgatg ttcggtgata acggctccgg tatgcactgc cacatgtctc
    22201 tgtctaaaaa cggcgttaac ctgttcgcag gcgacaaata cgcaggtctg tctgagcagg
    22261 cgctgtacta cattggcggc gtaatcaaac acgctaaagc gattaacgcc ctggcaaacc
    22321 cgaccaccaa ctcttataag cgtctggtcc cgggctatga agcaccggta atgctggctt
    22381 actctgcgcg taaccgttct gcgtctatcc gtattccggt ggtttcttct ccgaaagcac
    22441 gtcgtatcga agtacgtttc ccggatccgg cagctaaccc gtacctgtgc tttgctgccc
    22501 tgctgatggc cggtcttgat ggtatcaaga acaagatcca tccgggcgaa gccatggaca
    22561 aaaacctgta tgacctgccg ccagaagaag cgaaagagat cccacaggtt gcaggctctc
    22621 tggaagaagc actgaacgaa ctggatctgg accgcgagtt cctgaaagcc ggtggcgtgt
    22681 tcactgacga agcaattgat gcgtacatcg cactgcgtcg cgaagaagat gaccgcgtgc
    22741 gtatgactcc gcatccggta gagtttgagc tgtactacag cgtctaagtg ttttagttgc
    22801 cgtggaaact tttcgcctgt ctctggcagg cctgggatcg gtggcaagca catcacgccg
    22861 gatgcgacgc aaatgcgtct tatccggcct acacggtgat gatgtggtag gccggagcag
    22921 gtgagtcgct ctccaacgtg aagtttgtca gctatctgta gcccatctct gcatgggctt
    22981 ttttctccgt caattctctg atgcttcgcg ctttttatcc gtaaaaagct ataatgcact
    23041 aaaatggtgc aacctgttca ggagactgct ttatggcaac aggcacgcag cccgatgctg
    23101 ggcagatcct caactcgctg attaacagta ttttgttaat cgatgacaac ctggcgatcc
    23161 attacgccaa ccccgccgcg caacaactgc tcgcccaaag ctcccgcaaa ttgtttggta
    23221 caccgttacc ggaactgttg agctacttct cattaaatat cgagctgatg caagaaagtc
    23281 tggaggcggg gcaaggtttt accgataacg aagtgacgct ggtcatcgac gggcgctcgc
    23341 atatcctttc tgtgacggcc cagcgtatgc cggacggcat gatcctgctg gagatggctc
    23401 cgatggataa ccagcgccgc ttaagtcagg aacagctaca gcacgcccag caggttgctg
    23461 cccgtgattt agtgcgcggc ctggcacatg agattaaaaa tccgcttggc ggtttacgtg
    23521 gcgcggcgca gctgctcagc aaagcgttac ctgacccatc actactcgaa tataccaaag
    23581 tgattatcga acaggcggac cggctgcgaa atctggtcga ccgtctgttg gggccgcagc
    23641 tgcccggtac gcgcgttacc gaaagtattc acaaagtggc tgaacgcgtg gtaacgctgg
    23701 tgtcgatgga actgccggac aacgtgcggt tgattcgtga ttacgacccc agcctgccag
    23761 aactggcgca cgacccggat caaattgaac aggtcttgct gaatattgtg cgcaatgcgc
    23821 tacaggcgct ggggccggaa ggcggtgaaa tcattctgcg tacccgcacc gcgtttcaac
    23881 tgaccttaca cggcgaacgc taccggctgg cggcgcggat tgatgtggaa gataacgggc
    23941 caggcattcc gcctcatttg caggatacgc tgttttaccc gatggtcagc ggccgcgaag
    24001 gtggcaccgg gcttggctta tccatcgctc gtaatttgat tgatcagcat tcaggcaaaa
    24061 ttgaatttac cagttggcca gggcataccg agttctcggt ttacctgcct atcaggaaat
    24121 aaaggtgacg tttatgcaac gagggatagt ctgggtagtc gatgacgata gttccatccg
    24181 ttgggtgctt gaacgtgcgc tcgctggagc gggtttaacc tgtacgacat ttgagaacgg
    24241 cgcggaggta ctggaggcgc tggcgagcaa aacgccggat gtgctgcttt cagatatccg
    24301 tatgccggga atggacgggc tggcgctgct caagcagatt aaacagcgcc atccgatgct
    24361 tccggtcatc attatgaccg cacattccga tctggatgct gccgtcagcg cctatcaaca
    24421 aggggcgttt gattatctgc ccaaaccgtt tgatatcgac gaagccgtgg cgctggttga
    24481 gcgcgccatc agtcattacc aggaacagca gcagccgcgt aatgttcagc ttaacggccc
    24541 aacgaccgat atcatcggcg aagcgccagc catgcaggac gtgttccgta ttatcggtcg
    24601 gctttcgcgt tcttctatta gcgtgctgat taacggcgaa tccggcaccg gtaaagaact
    24661 ggtcgctcat gccctgcatc gccacagtcc gcgagccaaa gcgccattta tcgctctgaa
    24721 tatggcggct atcccgaagg atttgatcga atcagaactg tttggtcacg agaaaggcgc
    24781 gtttaccggc gcgaatacca ttcgtcaggg gcgttttgaa caggctgatg gcggtacatt
    24841 atttctcgat gaaattggcg atatgccgct ggatgtgcag acgcgtttgc tgcgcgtgct
    24901 ggcagacggc cagttttacc gcgttggcgg ctatgcgccg gtgaaagtgg atgtgcggat
    24961 tatcgctgcc actcaccaga atctcgaaca gcgggtgcag gaaggtaagt tccgtgagga
    25021 tctgttccac cgcctgaacg ttatccgcgt tcatctgccg ccgctgcgtg agcgtcggga
    25081 agatattccc cgcctggcgc gccatttttt acaggttgcc gcgcgagaac tgggcgtaga
    25141 agcgaagttg ctgcatccgg aaaccgaagc cgcgttgacg cgtctggcgt ggccaggcaa
    25201 cgtgcgccag ctggaaaaca cctgccgctg gctaacggta atggctgccg gacaggaagt
    25261 gttgattcag gatttgcctg gcgaactgtt tgaatcaacg gttgcggaga gtacttcgca
    25321 aatgcaaccg gacagttggg cgacgcttct tgcgcagtgg gcagacagag cgctacgttc
    25381 cggtcatcaa aatctgcttt ccgaagcgca gccagagctg gagcggacgt tactgacgac
    25441 cgcgttgcga catacgcagg ggcataaaca ggaagcggcg cggctactcg gctggggccg
    25501 caacactctg acgcgtaagt taaaagagct ggggatggag tgattcacgg cttgtgtgta
    25561 aagattgatt attgagcgca aattgctggt attttgcgct ttactgttcc gataagttca
    25621 gtatgatctt gcccggaaaa cggggagagt cattatgctg gaatcaataa ttaatctggt
    25681 atcgagtggc gcagttgaca gccacacacc gcaaactgcc gttgctgccg tgctgtgtgc
    25741 cgcgatgatt gggctgttta gctgaagctc gttgtttatg ccggatgcgg agaaagtcgt
    25801 aggcctgata agacgcgacc agcgccgcat caggcatcat gctcagatgc ctgatgcggc
    25861 gtaaacgcct tatccggcct acaaaagcaa taatttcaac aggttttgtt gcccagcgca
    25921 tcaggcaatc ttgttctcag cacattgatg gcgctttcgt tttctacttt gtaaacgaag
    25981 cgccattcac tatttaaatc acccgagaga actgctgcat ccgcgctttc tggcgcagat
    26041 aggtatcaaa gcacatgcaa atgttgcgga tcagcaagcg acctttcgcc gtcacctgta
    26101 ttcccttctc atccacatcc accagcccat cttttgctaa cggggcgagc agcttgagat
    26161 cttccgcaaa gtaatcagcg aagtgcaaat cccactgttt ctcaataggg gcgtaatcca
    26221 gacggaagtt gcagatgagc gacttaatca catcgcggcg aatacagtca tcacgcgtta
    26281 gcgcaatacc acgccacagc gcattgcctt gttcatccac ttgctgatag tactgcttca
    26341 actctttctg gttctgcgcg tagcagtcgc caatcatgct gatggcggaa acgcccatcc
    26401 ccagcagatc ggtatcgccc tgagtggtgt agccctggaa gttacgatgc agcacgcctt
    26461 cacgctgggc caccgccagc tcgtcatccg gacgggcaaa gtgatccata ccgataaact
    26521 gatagcccga ttgcgtcagg aaggcgatgg tttcctgcag gatatcgagt ttttgctgcg
    26581 gactcggcag gtcagcatct ttgattttgc gctgagcagc aaaaatggtc ggcagatgcg
    26641 cgtagttaaa gacactcaga cgatcggggt tcagctccgc cacacgtttc agggtaaagg
    26701 cgaaactctc cggcgtctgt ttcggcaggc cgtaaatcag gtcgatgttg gtggaggtaa
    26761 aaccaatctc acgcgcatgg ttaagcagtg caaagatgaa ctcttcatcc tgctcgcggt
    26821 taaccagacg ttgcacttct ttgttgaagt cctgcacgcc catgctcagg cgattaaagc
    26881 cttcggcgcg taaatgatcg agtacatcca gttcgatttc ccgcggatcg acttcgatcg
    26941 aaatctccgc atcggcattg aactggaagt tttcgcgcag cagcttcatc aggcggctga
    27001 tttgcgcttt attcagatac gtcggcgttc cgccgcccca gtgcaattgg ctgacgtgac
    27061 gcccggcgaa cagcggtgca cgatggacga tttcttgctc cagcgcgtcc agatactgat
    27121 cggccttgtg ctgctggcga gtaacaatct tattgcaacc gcagaagtaa caaagcttat
    27181 ggcagaacgg gatatgtacg tagagagata atggacgctc aggatagcgc gccacggctt
    27241 gtaaaaacgc ctgttcgccg aagtcttctg aaaactccag cgcggtcggg tacgaggtgt
    27301 atcgtggccc ggaatagtta tatttctgga tcagggccag atcccagtcg atttgctgta
    27361 cagacatgct cactccttcc gatggcgtct ctggcggcta cggcgtaccg gcggatgccc
    27421 gtttcgggtc atcagccggt tgcgcagcca cttttgtcgc cgcgacaacc gctgtagttt
    27481 aacgaataac cacaccagat aacatataac cggaagggtt atcagcagaa cgggaaggcc
    27541 cacggcggca atccgttagt tgccccgcag cagacgcatc atgtcttctt gcttctcgtc
    27601 ttcttcctct tcttcgtcat cgtcataaga gaggccgagt ttctgcatca actcatcaat
    27661 acgatccagt ttagcatcca cccaggattg ctcttcggca ctcagggttt cgcctgcttc
    27721 cagacgttcc agcagcgcat ccagacgctc atccgtttcc agtaactcca actccgcctg
    27781 cggtgaaagc ataggtttct cactcttcgg tttgtgctgt ttggtgactt tttcagtcac
    27841 gcccaatgga ataggggttt tactgccaat acgtggatct tttggtacgt tctggccttt
    27901 gctgcctgac gtggtgttac cgcccgctgc gcggctgccc ggcgcatgac cacgacgttt
    27961 tttctgacgc ttgcggtcac gagcttcctg attcagctct tcgcgcgttt tgcgacgcgc
    28021 ttttgcatga cctttgctgc gtgatggtga agatggtttc ataatggttc gtcttttagc
    28081 cgttttattc agtatagatt tgcggcggaa tctaacagaa agcaagcaaa gaaaaaaggc
    28141 gacagattac tctgtcgcct tttttcctga ctcataaccc ttaacgggtc ttacaatcct
    28201 tgcaggccgc caacacaccc tgtttttcca ttagccggaa caatccgtgt tgattccatt
    28261 tccgtttaat tacgtctccg gacgtttgtc ttcctgacaa tcctctgtct tcgcctcctg
    28321 gcgctcctga ccctcatcct gagtcattgt tcctgttagc gtcctcgctc tatgggtgtt
    28381 actttacgcc tttgctttaa acaaacaatc aaccgccatc agtatttgca cattttcaga
    28441 gttttatata aaagcaattc actgatttat atagcttatt tgacatgcat cgcagaattt
    28501 tctctgctat ttcgcataaa gactatcggc aatgtctcac aaagcgtatg gcttttactt
    28561 acaacgctca cgccgaaaaa tccgcctttt attatggttc aggtataatc gccacaaagc
    28621 tttgactgac ggagacgacc gctttgacta atttgaatta tcaacagacg cattttgtga
    28681 tgagtgcgcc tgatattcgc cacctacctt ccgataccgg aattgaagtg gcttttgcag
    28741 gccgttccaa cgcaggtaaa tccagcgcgc tgaacacgct gactaaccag aaaagcctgg
    28801 ctcgtacctc aaaaacccct ggacgcaccc agcttatcaa cctgtttgaa gtggctgacg
    28861 gcaagcgtct ggttgacttg cctgggtacg gttatgcgga agtcccggaa gagatgaagc
    28921 gcaaatggca gcgcgcgctc ggcgagtacc tcgaaaaacg tcagagcctg caaggtctgg
    28981 tggtgctaat ggatattcgc catccgctga aagatttgga tcagcagatg attgagtggg
    29041 cggtagacag caatatcgcc gtgctggtgt tgctgaccaa agcggacaaa ctggcaagcg
    29101 gcgcacgtaa agcgcaattg aatatggtgc gtgaagctgt actggcgttt aacggtgatg
    29161 tgcaggttga aacgttttct tcgttgaaga aacaaggcgt ggacaagctg cggcagaaac
    29221 tggatacctg gtttagcgag atgcagcctg tagaagaaac gcaggacggc gaataatttt
    29281 cttgccttaa tgcttgtgcc ggatgtggcg tatccggccc gtaaattcaa tagattacaa
    29341 ttctaccgtt ggcctgataa acatggcgca tcaggcattg cggatttttt ctttcgctca
    29401 ataaaaaacg ccccagtcat tactgactgg ggcggctaaa atattcagcc aaatccgatt
    29461 acgtgaagta aaaggtctga aagatagaac atcttacctc tgtaccctac gcgactaact
    29521 ttactctttt ttgttcagtt cagaaagcac tttttgtaat tttttttcag ttgttgcata
    29581 ggaatttcta atagccatca caaaacgtga cagcttatgt tgcttactta cgaaaaaagg
    29641 gcatgttcag gcgaatctta gtgcgcctga tcccagtttt cgccactccc cacttccacc
    29701 agcaacggca catccagacg ggtacagttt tccatcagtt gatgaatctg cttcgcaacg
    29761 gcatcgacat catctctatg aacttcaaat accagttcat cgtgtacctg catgatcata
    29821 cgtacacgcg gttgctcagc ctgtaaccac gcatcaacgg caatcatcgc ccgtttgata
    29881 atgtcggcgg cggttccctg cattggcgcg ttaatggctg cacgttcagc cgctgcacga
    29941 cgagcaccat tgctggattt gatatccggc agatacagac ggcgtccgtc cagcgtttca
    30001 acgtagccct gctctttcgc ctgagcacgg gtgcgttcca tatactccag cacgccaggg
    30061 tagcgttcga agtaaaggtc catgtacttc tgcgcttctt tacgtggaat gttcaattgc
    30121 cgcgccagac cgaaagcact catgccataa atcagaccaa agttgatcgc tttcgcgcta
    30181 cggcgttgct cgctggtgac ggtttccagt ggcaaaccaa acacttctgc cgccgttgcc
    30241 cggtggatat cttttccttc cgcgaatgcg gtcagcaagc ctttgtcacg cgagagatgc
    30301 gccataatgc gcagttcaat ctgcgagtag tccgctgaga caatcacata atcctctggc
    30361 gcaataaacg cctggcggat acggcgacct tcttcgttac gtaccggaat gttttgcagg
    30421 ttaggatcgg ttgacgataa acgtcccgtt gcagttactg cctggtgata agaggtatgc
    30481 acacgcccgg ttttcgggtt gatcatcagc ggcagcttgt cggtgtaggt cgatttcagc
    30541 ttcgccagac cacgatactc cagaatcact tttggcaacg gatagtccag cgccagttct
    30601 tccagtacct cttccgacgt tgacggcgcg ccacccggcg ttttcttcag cggtttaatg
    30661 ccctgttttt caaatagaat ggtttgtaac tgcttggtgg aagaaaggtt aaattcctca
    30721 cctgcaattt catgcgcttt cttttccagc tcagccagac gcaaggtaag ctcttcagaa
    30781 tgattgtgca gcactttcgg atcgatcttc acaccgttac gttcaatgcg tgaaagcacc
    30841 ggcaccagcg gcatttcgat attctcgaag acgttcaacg gccctttgtg tttttgcaga
    30901 tctggccaca ttttcagatg caactgcaag gtgacatccg catcttcggc ggcgtaacgt
    30961 ccggcctctt cgagggcaat ctggttaaag gtcagttgat ttttgccttt acccgcaatc
    31021 tcttcaaaag tgatggtttt gtgcttcaac caacgttccg cgaggctgtc catatcgtga
    31081 cgcccggcaa cgctattgag aatgtaggac tccagcatgg tatcaaacgc aatcccacgc
    31141 agctcaatgc cgtaattcgc cagaataccg cgatcgtatt tcaggttttg cccgaccttc
    31201 agcgcctttt catcttccag cagcggtttt agcaactcga gtgcacgctc gcgagagatt
    31261 tgatcgggcg catcaagata atcatgagca accggaatat atgccgctac gcctggctcg
    31321 atagcaaaag aaagcccgac caggttagca gagatgttat caaggctgtc ggtttcggta
    31381 tcaaatgcaa ataccggcgc tttttccagc ttcgcaatcc acgctttcag tgtttcttca
    31441 tcaaggatgg tgacgtagtt gtcataagaa atcaccgttg ccgtcacttc tggtgcttcg
    31501 tctgcaacac tggtttcctg tggcttcgcg gcgggttttg cccctttggc ctgtaaccat
    31561 ttgcccgctt cgacatcagc agtccagcgt ttgaactcat actttttgaa cagccccaac
    31621 aactcttccg ctgccggttg ctgcacttcc agttgttcac aggtcagctc cagttcaacg
    31681 tcggttttaa tcgtcgccag ctggtatgag agataagcaa cttctttgtt ttgctcgagc
    31741 ttcgctgcca ttgttttcgc gccacggaag ctcaacccag caattttttc tggctcggca
    31801 tacagcgtat ccagcccgcc aagaccttgc agcaatgcct gcgcggtttt ttcaccgacg
    31861 cccggtacgc caggaatgtt atcagaggag tcacccatca gcgccaggaa atcgatgatc
    31921 agttctggcg gcacgccgta cttattcacc acctcttccg gtccgaggat ggtattcgtc
    31981 atggtattga taagcgtaat atttggcgtc accagctgcg ccatatcttt atcgccagtg
    32041 ctgatcagca ccggacgccc ggctttttcg gcttcgcgcg ccagagtacc gataacgtcg
    32101 tccgcttcta cgccagaaac cgccagcagc ggcagtccca tcgctttaac catcgcgtgc
    32161 aagggttcga tttgtgcacg cagatcgtcc ggcattggcg ggcgatgtga tttgtaatgt
    32221 tcaaacagtt catcacgaaa ggtttttccc ttggcgtcaa agaccaccgc tgcatgcgtc
    32281 ggtttatatt gcatgatcag actgcgcagc atgttgagga caccatacat cgcaccggtc
    32341 ggctcgcctg cgctgttagt cagcggagga aacgcgtgat atgcgcgata aagataagat
    32401 gaaccatcta caaggataag tggattttgg gggatctgaa ccataatgtc cgtgcctgtt
    32461 tatcagatta tgggtaaagg atgccacaga caggataaaa acatgagttt ttcaccgctt
    32521 ttcgtgaaaa tcttttgtag atcttctgga tcgctcgcaa atcgtcatgt ggataacttt
    32581 gtgcataaat tatttacatc gcttttaatt tattatcatg ctttttacag catgatgctt
    32641 gtctttgttt ttcatgcagt taaaagtaaa gccatccctg ataattgaga taatgggatt
    32701 ttttctaatg tggatagata tgaattattt ttctccttaa ggatcatccg ttatttgggt
    32761 cgttttctgc taaaatctgc gccttgcgct tctttagcgc actgtctatg gctaaccttt
    32821 tgaataaatt cattatgacg agaatactcg ctgcgataac ccttttgctg agtatcgtat
    32881 tgaccatttt ggtcactatt ttttgttccg tcccgatcat cattgccggg attgtaaaac
    32941 tattgctacc tgtgccagtc atttggcgaa aggtttcgcg tttttgtgat tttatgatgt
    33001 attgctggtg tgaaggtctg gcggtattac tgcatctgaa cccacacctg caatgggaag
    33061 ttcacgggct ggaagggtta agtaagaaga actggtatct gcttatttgt aaccaccgta
    33121 gttgggcaga tattgtcgta ctgtgcgtgc tgtttcgtaa gcacattccg atgaataaat
    33181 atttcctcaa gcaacagctg gcctgggtgc catttcttgg cctggcgtgc tgggcgctgg
    33241 atatgccgtt tatgaagcgt tattcccgcg cttatttatt acgtcatccg gagcgacgtg
    33301 gtaaagatgt tgaaaccact cggcgttctt gtgaaaagtt tcgcctgcat cccaccacca
    33361 ttgtcaattt cgttgaaggc tcccgtttca cgcaagaaaa acatcagcaa acccactcca
    33421 cttttcaaaa cttgttgcca ccaaaggcgg caggcattgc gatggcgcta aatgtactgg
    33481 gtaaacaatt cgataaactg cttaatgtta cgctgtgtta tccggacaat aaccgtcagc
    33541 cgttcttcga tatgttaagc ggtaaactga cgcggattgt cgtacatgtg gatttacagc
    33601 ctattgccga tgagttacat ggcgactaca tcaatgacaa aagctttaag cgccattttc
    33661 agcaatggct gaactcattg tggcaggaaa aagaccggct tctgacgtct ctcatgtcat
    33721 cacagcgtca gaataagtaa gttttactcg cctctgaatg agcagaggcg agtgagtatt
    33781 ttaatgaaca aaacgtccgg cacgagacat aaattcttct tcgctcatct cctgtccgtt
    33841 aaaaacaact ttacccggtg tataacgcag ctgcagcgag gcggtattgt tgtcaatcgt
    33901 gattaactga aacatctgac ctaatgtcat catcccgctg atttgtttat cagcctgctt
    33961 ttgcgctttt tccgcatcca ttccttcaga taaattaagc tgttttgcgg tttctgtggc
    34021 gacattaagc ggtaacttca catcaaaatt gagcgatttg atatctttgt ttgtggatga
    34081 tgaagatttg gctgggtcgg caatactgat atccagattg gcatttagtt cgccgagtgc
    34141 gttcttccat cttaccggtt gtttaatggc cggctcactt tgttgtaata acggtaaata
    34201 ctctttgaac aatgcagcat tcacttcttg cagagcaact tcatcgtttg ctaactcagg
    34261 atgtgcagca agctgcttct gcatcgcaat gttatactgg atgataaatt ggcgcactgc
    34321 tgagggatca atagattcag caatcaatga ccactcacca ctaccgagtt gctgattccc
    34381 ttttgttaac ttatcaagtt cgtaggtcag attgacattg atataatctt tgtctttaac
    34441 gcgatccagc ctggtttttg caacgaaagc atcgatttgg gcaacgtctt ccccgtgatt
    34501 gataatgtta atctgattaa atttcgactc gctttcacca accggaaatt tcttttcttc
    34561 taatcgcgcc agagaatcaa tggtaaaact ttttgccgtt actttgttca ttggtgataa
    34621 ttgcagaaca atatcttcga ctttgccttc aatatccagg ttagacaatg aactaccatc
    34681 accattaaaa gtaaactggc cctcaccaaa agaaaacttt ccatactctg caggggcaac
    34741 atctaatgtc gtagagaatg agccaccaaa cgcgaatcgc aatgtcgctt ccacgggcga
    34801 tttatttttc gcggcgataa atagcggttg tgtcagttca ttattcacta agttcacttt
    34861 tgccgctgcc agtgctggga tgacattacc atgcattaac attgtgatgg gcaacggacc
    34921 gtgctcaaca tccacatcaa atacaacttt ctggcctggc ttgatattga gatcgggtgc
    34981 accgttatcg aatgtcattt gcatttgaaa acgggaatta aaaaagcctt tgtcaaaatt
    35041 ttgataactt aacgtcatat cgtaggcatg ttcacctttc tttttagcat cgttaaaatc
    35101 tttaataaat ttttcgacac caggctgaat ttgcgtacct gtgtaccatg tgccaccacc
    35161 ccagattacg gctaacgcaa caataacacc tgtagctgac ttacgtatca tataaatatt
    35221 ccctgataaa acagcaaaac tttgaatatc cacttatgct gaaataatgt ccagcggcag
    35281 gatgcattat cagaatgtat ttatatttat taaataataa aaaaagcccg tgaatattca
    35341 cgggctttat gtaatttaca ttgaattatt ttttctcgga cagatatttc actgtattag
    35401 catactgctg aacaaaaaca tccatattgc tggtatccat accctgcgga ttcagctgat
    35461 atttaccgtt aacaaacatc gccggaacac cacgcaattg cacgtcagct gcagcttttt
    35521 cctgctgagc gaccagagat ttgaccacga agctgttcca ggccgcgtcg tactcttcac
    35581 ctttaatacc tgcgttgata aatacatcgc ggatatcaga tgctgaacga atggtctggg
    35641 ttttctgtac gccttcaaac agcggaacag tgactttgtc ttccacgccc agcgccatcg
    35701 ccacagccca tgcctgagtc agatctttgc cgacgtcccc ccccatgaag ttgacgtggt
    35761 atttagtcat cttcacgcct tccggcagtt ttttcttcac gttatcagaa atatgcagaa
    35821 cttcttcaaa ctgatagcag tgcgggcaga agaaagagaa aaactccagc acttgcggcg
    35881 cgccagctac cggtttttcc agggtagtgt actgtttacc atcttcatac tgcgccgccg
    35941 atgcgctaaa cgctaaaact aaaccagcca gcgccagcca aatctttttc atgatctact
    36001 ctctccgatt aatacattgg tgttaattgc aaagggggtt cttgtagaac ttttgcctgt
    36061 tctataaaag tcgccgtctg tcgtagccag taatcttccc cggttaacca cgggaaattt
    36121 ttcgggaacg cgggatcagc ccaacgccgc attagccagg caagataata aaccaaacgc
    36181 atggcgcgta aaggttcaat cagtccgatt tcagcggtgt cgaactcgct aaattcttca
    36241 taagcttcaa taatagtttc cagttgcatc cgctgctcgg ctttatcgcc attgagcaac
    36301 atccacaaat cctgaatagc tggaccatta cgtgcatcat ccagatcaac aaacattgga
    36361 ccatcgcgcc agagaatatt cccggcgtgg cagtctccat gtagccgcag aacggtgaaa
    36421 tcttcccgcc agtgtgctgt aacggcggcg atcagctcat ctgtcgcttt caggaatgcc
    36481 gctttcaacc cggaaggtat cagtgtagcg tcctcaaaca gcttgcgtgg ctcaatgaga
    36541 tattcattca gaccgatggt cgggcgatgg ataaaaagct gtttgcgccc cgtctggtgc
    36601 atacgcccta aataacgccc aaccgcttcc atctgatcga tattatcagc ttcgaactgg
    36661 cgaccaccga cgcttggaaa aacagcgaaa taaaatccct gatgattcaa taaagtctga
    36721 ccgttaaaag ccacaggtgc tgcgaccgga acttcatcat ttaccagctg caacgcaaat
    36781 tgatgttctt cgaggatttg atcggctgtc caacgttcag gacgataaaa tttgacgaca
    36841 aaacgtcgac gatcttcgtc ctgaaattga tagacacggt tttcatagct gttaagcggg
    36901 gtaagaccgg aatccacccg gatcccttgc tcaaacagag cgtccatgat ggtatccggg
    36961 tgtagtgtct ggaaagtaaa agcgctgttg ttcatcccat catccggaaa acattacgaa
    37021 tgatgaagga tatcatttca cgatgatttt ggtggcgccg cttacaagct tttactcttt
    37081 aattacgccg cgagcgcgta acagcgccgt tttgaagtct tcttcataat ctttctgcaa
    37141 acccgggatc accgcatctt tcgcggaatc acgcattttc aggtgataga tcagaatgtc
    37201 atccgtcaaa tccgccagtt cgccgtcaaa acctgactct ttcgccaatt tctgcaaaaa
    37261 ttgcaacagg ttaaggtctg gctctttttg ccaggctggc tggaggagtt caataacttc
    37321 attcagacgt ttacatttca tagtgatgct ccttactctt gagacagaca cgttagcagg
    37381 gtcaatccca caataaaaga ggcgatatcg gtgaatctga tgacgacgat aacaggcgtt
    37441 gtgctggcag gcggtaaagc cagacgaatg ggcggcgtag ataaaggatt gcttgaatta
    37501 aacggcaaac cattatggca acatgtcgct gacgcgctta tgacgcagct ctctcacgtc
    37561 gtggttaatg ctaatcgtca tcaggaaatc tatcaggcag gcggtctgaa agtgattgaa
    37621 gattcactgg cggattaccc aggccctctg gcaggaatgc tttcagtaat gcagcaggaa
    37681 gctggtgagt ggtttttgtt ttgcccgtgc gatacgcctt acattccccc tgatttagca
    37741 gcaaggctta atcatcagcg caaagatgcg cctgtcgtgt gggtccatga cggtgaacgc
    37801 gatcacccga ctattgctct ggtaaaccgc gctattgagc ctttattact ggaatatctg
    37861 caagcaggag aacgccgggt aatggcattt atgcgtctgg ctggcggtca tgcggttgat
    37921 ttcagcgatc ataaagatgc atttgttaac gtgaatacgc cagaggagct tgcccgatgg
    37981 caggaaaaac gatgataccg ttactcgcct ttgccgcgtg gagtggtacc ggaaaaacta
    38041 cgcttttgaa aaaactgatc ccggcattat gcgccagagg gatccgtcca gggctgatta
    38101 agcatacgca ccatgatatg gatgttgata agccaggcaa agatagctat gagctgcgca
    38161 aggctggcgc ggcacaaacc atcgttgcca gccagcaacg atgggccttg atgacggaaa
    38221 caccagacga agaagagctg gatctacagt ttctcgcaag tcgaatggat acctcaaagc
    38281 tggatttgat tctggtcgaa gggtttaagc atgaagagat cgcaaagatt gtgctgtttc
    38341 gcgatggagc cggacatcga cctgaagaat tagtgataga caggcatgtt attgctgtag
    38401 ccagtgatgt gccgcttaat cttgatgtcg cattactgga tattaatgat gttgaggggc
    38461 tggctgattt tgtggtggag tggatgcaaa agcagaacgg ataagcaaga gtaggctgga
    38521 taagacgcgc cagcgtcgca tccggcattt ttttctgcac caa
//
LOCUS       DAPHKZ010000034        38454 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.034, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000034 DAPHKZ010000000
VERSION     DAPHKZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38454
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.034"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(155..346)
                     /locus_tag="RH288_001822"
     CDS             complement(155..346)
                     /locus_tag="RH288_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2633 family protein"
                     /protein_id="HDV4030878.1"
                     /translation="MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHH
                     QSKKEAQQSTLSVESPVQR"
     gene            364..516
                     /locus_tag="RH288_001823"
     CDS             364..516
                     /locus_tag="RH288_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030879.1"
                     /translation="MSHAVDGTYIKAQQDKMVNSSLCKKASVDTYFNVMEVNLIIYND
                     DVIMMN"
     gene            698..2941
                     /gene="pdeF"
                     /locus_tag="RH288_001824"
     CDS             698..2941
                     /gene="pdeF"
                     /locus_tag="RH288_001824"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeF"
                     /protein_id="HDV4030880.1"
                     /translation="MKLNATYIKIRDKWWGLPLFLLSLILPIFAHINTFAHISSGEVF
                     LFYLPLALMISMMMFFSWAALPGIALGIFVRKYAELGFYETLSLTANFIIIIILCWGG
                     YRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
                     FNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDAKVTKKEFAL
                     WLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMI
                     SIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVVRRIQRLAYVDP
                     VVHLPNVRALNRALRDAPWSALCYLRIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLE
                     PGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRS
                     PVNHIYLLLGELNTVAELSIVTNAPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNH
                     FFLMAQPITGMRGDVYHEILLRMKGENDELISPDSFLPVAHEFGLSSSIDMWVIEHTL
                     QFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLAKYQIEAWQLIFEVTESNALT
                     NVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKKMLVVAEYVENEEIREAVLSLGIDYMQGYLIGKPQPLIDTLNEI
                     EPIRESA"
     gene            complement(2980..4521)
                     /gene="ppx"
                     /locus_tag="RH288_001825"
     CDS             complement(2980..4521)
                     /gene="ppx"
                     /locus_tag="RH288_001825"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HDV4030881.1"
                     /translation="MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPI
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASG
                     TIKAAHEVLMEMGEKDGIITPERLEKLVKEILRHRNFASLSLPGLSEERKTVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQAR
                     RVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNS
                     DLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEEST
                     PEIAA"
     gene            complement(4526..6592)
                     /gene="ppk1"
                     /locus_tag="RH288_001826"
     CDS             complement(4526..6592)
                     /gene="ppk1"
                     /locus_tag="RH288_001826"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HDV4030882.1"
                     /translation="MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
                     IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGM
                     CSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEV
                     ATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIK
                     SLEQPE"
     gene            complement(6764..7402)
                     /gene="purN"
                     /locus_tag="RH288_001827"
     CDS             complement(6764..7402)
                     /gene="purN"
                     /locus_tag="RH288_001827"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDV4030883.1"
                     /translation="MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLE
                     RARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
                     SEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE"
     gene            complement(7402..8439)
                     /gene="purM"
                     /locus_tag="RH288_001828"
     CDS             complement(7402..8439)
                     /gene="purM"
                     /locus_tag="RH288_001828"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDV4030884.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPL
                     ADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQW
                     PEVFNWLQTAGNVEHHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            8764..9390
                     /gene="upp"
                     /locus_tag="RH288_001829"
     CDS             8764..9390
                     /gene="upp"
                     /locus_tag="RH288_001829"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDV4030885.1"
                     /translation="MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            9476..10765
                     /gene="uraA"
                     /locus_tag="RH288_001830"
     CDS             9476..10765
                     /gene="uraA"
                     /locus_tag="RH288_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDV4030886.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVLFRPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
                     ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTL
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVI
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGM
                     ALATIVGIGLSLIFKLISVLRPEEVVLDAEDADITDK"
     gene            10815..11561
                     /gene="hda"
                     /locus_tag="RH288_001831"
     CDS             10815..11561
                     /gene="hda"
                     /locus_tag="RH288_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HDV4030887.1"
                     /translation="MVNFSRFCEILVEVSLNTPAQLSLPLYLPDDETFASFWPGDNSS
                     LLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVP
                     EVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNL
                     GLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRT
                     LFMTLDQLDRASITAQRKLTIPFVKEILKL"
     gene            complement(11699..12058)
                     /gene="arsC"
                     /locus_tag="RH288_001832"
     CDS             complement(11699..12058)
                     /gene="arsC"
                     /locus_tag="RH288_001832"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416990.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HDV4030888.1"
                     /translation="MTKQVKIYHNPRCSKSRETLNLLKENGVEPEVVLYLETPADAAT
                     LRDLLKILGMNSARELMRQKEDLYKELNLADSSLSEEALIQAMVDNPKLMERPIVVAN
                     GKARIGRPPEQVLEIVG"
     gene            complement(12079..13542)
                     /gene="bepA"
                     /locus_tag="RH288_001833"
     CDS             complement(12079..13542)
                     /gene="bepA"
                     /locus_tag="RH288_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HDV4030889.1"
                     /translation="MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTL
                     SIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSNANSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFD
                     PQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYL
                     AKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQP
                     LLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQP
                     QEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLL
                     SSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM"
     gene            13755..14816
                     /locus_tag="RH288_001834"
     CDS             13755..14816
                     /locus_tag="RH288_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDV4030890.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLV
                     AIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
                     TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVL
                     EMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVIHAWPDGQIAQE"
     gene            complement(14854..15702)
                     /locus_tag="RH288_001835"
     CDS             complement(14854..15702)
                     /locus_tag="RH288_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter"
                     /protein_id="HDV4030891.1"
                     /translation="MRNKLSFDLQLSARKAAIAERIAAHKIARSKVSVFLMAMSAGVF
                     MAIGFTFYLSVIADAPSSQALTHLVGGLCFTLGFILLAVCGTSLFTSSVMTVMAKSRG
                     VISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTF
                     TESVSLGIMCNLMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPF
                     AIAIRHFAPPPFWQLAHSSADNFPALTVSHFITANLLPVMLGNIIGGAVLVSMCYRAI
                     YLRQEP"
     gene            complement(15724..17736)
                     /gene="hyfR"
                     /locus_tag="RH288_001836"
     CDS             complement(15724..17736)
                     /gene="hyfR"
                     /locus_tag="RH288_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HyfR"
                     /protein_id="HDV4030892.1"
                     /translation="MAMSDEAMFAPPQGITIEAVNGMLAERLAQKHGKASLLRAFIPL
                     PPPFSPVQLIELHVLKSNFYYRYHDDGSDVTATTEYQGEMVDYSRHAVLLGSSGMAEL
                     RFIRTHGSRFTSQDCTLFNWLARIITPVLQSWLNDEEQQVALRLLEKDRDHHRVLVDI
                     TNAVLSHLDLDDLIADVAREIHHFFGLASVSMVLGDHRKNEKFSLWCSDLSASHCACL
                     PRCMPGESVLLTQTLQTRQPTLTHRADDLFLWQRDPLLLLLASNGCESALLIPLTFGN
                     HTPGALLLAHTSSTLFSEENCQLLQHIADRIAIAVGNADAWRSMTDLQESLQQENHQL
                     SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLS
                     PRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGD
                     LPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRL
                     NVFPLELPPLRDRPEDIPLLAKHFTQKMARHMNRAIDAIPTEALRQLMSWDWPGNVRE
                     LENVIERAVLLTRGNSLNLHLNVRQSRLLPTLNEDSALRSSMAQLLHPTTPENDEEER
                     QRIVQVLRETNGIVAGPRGAATRLGMKRTTLLSRMQRLGISVREVL"
     gene            complement(17766..18179)
                     /gene="hyfJ"
                     /locus_tag="RH288_001837"
     CDS             complement(17766..18179)
                     /gene="hyfJ"
                     /locus_tag="RH288_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416985.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 assembly chaperone HyfJ"
                     /protein_id="HDV4030893.1"
                     /translation="MTEECGEIVFWTLRKKFVASSDEMPEHSSQVMYYSLAIGHHVGV
                     IDCLNVAFRCPLTEYEDWLALVEEEQARRKMLGVMTFGEIVIDASHTALLTRAFAPLA
                     DDATSVWQARSIQFIHLLDEIVQEPAIYLMARKIA"
     gene            complement(18172..18930)
                     /gene="hyfI"
                     /locus_tag="RH288_001838"
     CDS             complement(18172..18930)
                     /gene="hyfI"
                     /locus_tag="RH288_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfI"
                     /protein_id="HDV4030894.1"
                     /translation="MSPVLTQHVSQPITLDEQTQKMKRHLLQDIRRSAYVYRVDCGGC
                     NACEIEIFAAITPVFDAERFGIKVVSSPRHADILLFTGAVTRAMRMPALRAYESAPDH
                     KICVSYGACGVGGGIFHDLYSVWGGSDTIVPIDVWIPGCPPTPAATIHGFAVALGLLQ
                     QKIHAVDYRDPTGVTMQPLWPQIPPSQRIAIEREARRLAGYRQGREICDRLLRHLSDD
                     PTGNRVNTWLRDADDPRLNSIVQQLFRVLRGLHD"
     gene            complement(18927..19472)
                     /gene="hyfH"
                     /locus_tag="RH288_001839"
     CDS             complement(18927..19472)
                     /gene="hyfH"
                     /locus_tag="RH288_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit H"
                     /protein_id="HDV4030895.1"
                     /translation="MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACG
                     ACACACPANALTIQTDDQQNSRTWQLYLGRCIYCGRCEEVCPTRAIQLTNNFELTVTN
                     KADLYTRATFHLQRCSRCERPFAPQKTIALAAELLAQQQNAPQNREMLWAQASVCPEC
                     KQRATLINDDTDVLLVAKEQL"
     gene            complement(19482..21149)
                     /gene="hyfG"
                     /locus_tag="RH288_001840"
     CDS             complement(19482..21149)
                     /gene="hyfG"
                     /locus_tag="RH288_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfG"
                     /protein_id="HDV4030896.1"
                     /translation="MNVNSSSNRGEAILAALKTQFPGAVLDEERQTPEQVTITVKINL
                     LPDVVQYLYYQHDGWLPVLFGNDERTLNGHYAVYYALSMEGAEKCWIVVKALVDADSR
                     EFPSVTPRVPAAVWGEREIRDMYGLIPVGLPDQRRLVLPDDWPEDMHPLRKDAMDYRL
                     RPEPTTDSETYPFINEGNSDARVIPVGPLHITSDEPGHFRLFVDGEQIVDADYRLFYV
                     HRGMEKLAETRMGYNEVTFLSDRVCGICGFAHSVAYTNSVENALGIEVPQRAHTIRSI
                     LLEVERLHSHLLNLGLSCHFVGFDTGFMQFFRVREKSMTMAELLIGSRKTYGLNLIGG
                     VRRDILKEQRLQTLKLVREMRADVSELVEMLLATPNMEQRTQGIGILDRQIARDLRFD
                     HPYADYGNIPKTLFTFTGGDVFSRVMVRVKETFDSLAMLEFALDNMPDTPLLTEGFSY
                     KPHAFALGFVEAPRGEDVHWSMLGDNQKLFRWRCRAATYANWPVLRYMLRGNTVSDAP
                     LIIGSLDPCYSCTDRVTLVDVRKRQSKTVPYKEIERYGIDRNRSPLK"
     gene            complement(21139..22719)
                     /gene="hyfF"
                     /locus_tag="RH288_001841"
     CDS             complement(21139..22719)
                     /gene="hyfF"
                     /locus_tag="RH288_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit F"
                     /protein_id="HDV4030897.1"
                     /translation="MSYSVMFALLLLTPLLFSLLCFACRKRRLSATRTVTVLHSLGIT
                     LLLILALWVVQTAADAGEIFAAGLWLHIDGLGGLFLAILGVIGFLTGIYSIGYMRHEV
                     AHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRS
                     SLEAAWKYIIICTVGVAFGLFGTVLVYANAASVMPQAEMAIFWSEVLKQSSLLDPTLM
                     LLAFVFLLIGFGTKTGLFPMHAWLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIII
                     CQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVENMGLVAVELGIGGP
                     LGIFAALLHILNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGAL
                     ALAGMPPFNIFLSEFMTITAGLARNHLLIIVLLLLLLTLVLAGLVRMAARVLMAKPPQ
                     AVNRGDLGWLTTSPMVILLVMMLAMGTHIPQPVIRILAGASTIVLSGTHDLPAQRSTW
                     HDFLPSGTASVSEKHSER"
     gene            complement(22724..23374)
                     /gene="hyfE"
                     /locus_tag="RH288_001842"
     CDS             complement(22724..23374)
                     /gene="hyfE"
                     /locus_tag="RH288_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 membrane subunit"
                     /protein_id="HDV4030898.1"
                     /translation="MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSI
                     FATLSCLFAAEQLLIWSASAFITKVLLVPLIMTYAARNIPQNIPEKALFGPAMMALLA
                     ALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMEN
                     GSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG"
     gene            complement(23386..24825)
                     /gene="hyfD"
                     /locus_tag="RH288_001843"
     CDS             complement(23386..24825)
                     /gene="hyfD"
                     /locus_tag="RH288_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfD"
                     /protein_id="HDV4030899.1"
                     /translation="MENLALTTLLLPFIGALVVSFSPQRRAAEWGVLFAALTTLCMLS
                     LISAFYQADKVAVTLTLVNVGDVALFGLVIDRVSTLILFVVVFLGLLVTIYSTGYLTD
                     KNREHPHNGTNRYYAFLLVFIGAMAGLVLSSTLLGQLLFFEITGGCSWALISYYQSDK
                     AQRSALKALLITHIGSLGLYLAAATLFLQTGTFALSAMSELHGDARYLVYGGILFAAW
                     GKSAQLPMQAWLPDAMEAPTPISAYLHAASMVKVGVYIFARAIIDGGNIPHVIGGVGM
                     VMALVTILYGFLMYLPQQDMKRLLAWSTITQLGWMFFGLSLSIFGSRLALEGSIAYIV
                     NHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLHTLPLPGVGFCVAALAITGVPPFNGF
                     FSKFPLFAAGFALSVEYWILLPAMILLMIESVASFAWFIRWFGRVVPGKPSEAVADAA
                     PLPGSMRLVLIVLIVMSLISSVIAATWLQ"
     gene            complement(24842..25789)
                     /gene="hyfC"
                     /locus_tag="RH288_001844"
     CDS             complement(24842..25789)
                     /gene="hyfC"
                     /locus_tag="RH288_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416978.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfC"
                     /protein_id="HDV4030900.1"
                     /translation="MRQTLCDGYLVIFALAQAVILLMLTPLFTGISRQIRARMHSRRG
                     PGIWQDYRDIHKLFKRQEVAPTSSGLMFRLMPWVLISSMLVLAMALPLFITVSPFAGG
                     GDLITLIYLLALFRFFFALSGLDTGSPFAGVGASRELTLGILVEPMLILSLLVLALIA
                     GSTHIEMISNTLAMGWNSPLTTVLALLACGFACFIEMGKIPFDVAEAEQELQEGPLTE
                     YSGAGLALAKWGLGLKQVVMASLFVALFLPFGRAQELSLACLLTSLVVTLLKVLLIFV
                     LASIAENTLARGRFLLIHHVTWLGFSLAALAWVFWLTGL"
     gene            complement(25800..27817)
                     /gene="hyfB"
                     /locus_tag="RH288_001845"
                     /pseudo
     CDS             complement(25800..27817)
                     /gene="hyfB"
                     /locus_tag="RH288_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit B"
     gene            complement(27817..28434)
                     /gene="hyfA"
                     /locus_tag="RH288_001846"
     CDS             complement(27817..28434)
                     /gene="hyfA"
                     /locus_tag="RH288_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416976.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfA"
                     /protein_id="HDV4030901.1"
                     /translation="MNRFVVAEPLWCTGCNTCLAACSDVHKTQGLQQHPRLALAKTST
                     ITAPVVCHHCEEAPCLQVCPVNAISQRDDAIQLNESLCIGCKLCAVVCPFGAISASGS
                     RPVNAHAQYVFQAEGSLKNGEENVLPQHALLRWEPGVQTVAVKCDLCDFLPEGPACVR
                     ACPNQALRLITDDSLQRQMKEKQRLAASWFANGGEDPLSLTQEQR"
     gene            complement(28687..29157)
                     /gene="bcp"
                     /locus_tag="RH288_001847"
     CDS             complement(28687..29157)
                     /gene="bcp"
                     /locus_tag="RH288_001847"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDV4030902.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA"
     gene            complement(29157..29729)
                     /locus_tag="RH288_001848"
     CDS             complement(29157..29729)
                     /locus_tag="RH288_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HDV4030903.1"
                     /translation="MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIVMKRTTARPRPPMPASVWVQVDV
                     ADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            29875..30753
                     /gene="dapA"
                     /locus_tag="RH288_001849"
     CDS             29875..30753
                     /gene="dapA"
                     /locus_tag="RH288_001849"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDV4030904.1"
                     /translation="MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGT
                     TGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
                     KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMC
                     KLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITD
                     SGRETVRAALKHAGLL"
     gene            30770..31804
                     /gene="bamC"
                     /locus_tag="RH288_001850"
     CDS             30770..31804
                     /gene="bamC"
                     /locus_tag="RH288_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HDV4030905.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEA
                     APLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGD
                     TASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAAN
                     AAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNM
                     AVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFSK"
     gene            32017..32730
                     /gene="purC"
                     /locus_tag="RH288_001851"
     CDS             32017..32730
                     /gene="purC"
                     /locus_tag="RH288_001851"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDV4030906.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLV
                     KRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSL
                     GGLIEAYEAVARRLGVQLD"
     gene            32898..33761
                     /locus_tag="RH288_001852"
     CDS             32898..33761
                     /locus_tag="RH288_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HDV4030907.1"
                     /translation="MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVV
                     LVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMG
                     KTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHSMQ
                     QQGVLETGDLEEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGD
                     PAQCNTFGKSI"
     gene            33776..35791
                     /gene="tmcA"
                     /locus_tag="RH288_001853"
     CDS             33776..35791
                     /gene="tmcA"
                     /locus_tag="RH288_001853"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HDV4030908.1"
                     /translation="MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFEHTLKLRDALP
                     GDWLWISPRPDAENHCSPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWL
                     VLLLPVWEEWENQPDADSLRWSDCPDPIATPHFVQHLKRVLTADNEAILWRQNQPFSL
                     AHFTPRTDWYPATGAPQPEQQQLLKQLMTMPPGVAAVTAARGRGKSALAGQLISRIVG
                     RAIVTAPAKASTDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLHQLV
                     SRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEAL
                     VFDDENFTHTPQGNIVISAFEQTLWQSDPETPLKVYQLLSGAHYRTSPLDLRRMMDAP
                     GQHFLQAAGENEIAGALWLVDEGGLSQQLSQAVWAGFRRPRGNLVAQSLAAHGNNPLA
                     ATLRGRRVSRIAVHPARQREGTGRQLIAGALQYTQDLDYLSVSFGYTGELWRFWQRCG
                     FVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEREHYRLRRDAQALAQWNGETLPVD
                     PLNDAVLSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELALPALRGRLQKNASDAQ
                     LCTTLKLSGRKMLLVRQREEAAQALFALNDVRTERLRDRITQWQLFH"
     gene            35865..36563
                     /gene="ypfH"
                     /locus_tag="RH288_001854"
     CDS             35865..36563
                     /gene="ypfH"
                     /locus_tag="RH288_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416968.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDV4030909.1"
                     /translation="MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGNWFAPLFP
                     DALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQARVDAIMPTFIETVRYWQKQSGVGA
                     NATALIGFSQGAIMVLESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
                     VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEAL
                     SGGKPGDDDVIEMM"
     gene            complement(36673..36873)
                     /locus_tag="RH288_001855"
     CDS             complement(36673..36873)
                     /locus_tag="RH288_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HDV4030910.1"
                     /translation="MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPP
                     HRDFNDKWDDDDDWPKKDQPKK"
     gene            complement(36901..38028)
                     /gene="dapE"
                     /locus_tag="RH288_001856"
     CDS             complement(36901..38028)
                     /gene="dapE"
                     /locus_tag="RH288_001856"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HDV4030911.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMD
                     FADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLV
                     GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIE
                     WDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            complement(38032..38388)
                     /locus_tag="RH288_001857"
     CDS             complement(38032..38388)
                     /locus_tag="RH288_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HDV4030912.1"
                     /translation="MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLND
                     FINELGWEALLNTRGTTWRKLDETTRNKITDAASAAALMTEMPAIIKRPLLCVPGKPM
                     LLGFSDSSYQQFFHEV"
BASE COUNT         9391 a         9902 c        10105 g         9056 t
ORIGIN      
        1 atatttattt cgcagccaaa caggataaac atcagtcagg ataaagacgt aaaatttaag
       61 atgaaagaat atctgccgct ttgataatcc caaacagcaa aagcatccga cagcgaagtg
      121 ccgttatgtt ctgtgaaagt ggagaaggta accgctaacg ttgtaccggt gattcgacgg
      181 agagtgtgga ttgctgagct tcttttttgc tctgatggtg ctgccaggca ccgacggacg
      241 agtagataaa acggccaaag aagaagataa agctgatgag cagtacgata cgggtcatgc
      301 gactgttaaa tcggtgtcgt tttcgcatac tggttgcctg actcacaaaa ggttccttga
      361 agtatgtccc acgctgtgga cggtacttac attaaggcac aacaggacaa aatggtcaat
      421 tcttcgttat gtaaaaaagc gtcagtggat acatatttta atgttatgga agttaattta
      481 attatttaca atgatgatgt aataatgatg aattaacatg ataaacgtaa taattcatta
      541 atcagggtta ttttgtttga tatatatcaa ttggtacttt catatgacac ttagaatcaa
      601 tgctctctat agtgatgaat aatcatcatt cgaagtcagg tgggatgcct gtctgaatac
      661 acctccttca ggatgtgggg gattctgctg agcatctatg aaactgaatg caacttatat
      721 aaaaatacgt gataaatggt gggggcttcc gctgttcctg ctttctttaa tcttgcccat
      781 tttcgcccac attaatactt tcgcgcatat ttcttccggt gaggtttttc tcttttatct
      841 gcctctggca ctgatgatca gcatgatgat gtttttcagc tgggcggcat tgccagggat
      901 cgccttaggg atttttgtcc gcaaatatgc agagctgggt ttttacgaaa cgctatcatt
      961 aacggctaat tttattatca ttatcattct ctgttggggc ggttacaggg tctttactcc
     1021 ccggcgtaac aacgtttcac atggtgatac ccgtttaatt tcccagcgta tattctggca
     1081 gattgtgttt cctgcaacgc tgtttctgat acttttccag tttgctgcat ttgtaggatt
     1141 actggcgagc agagaaaatc tggtcggtgt catgcctttt aacctcggga ctttaatcaa
     1201 ttatcaggcc ttactggtgg gtaatctgat cggtgtcccg ctgtgctact tcatcattcg
     1261 ggtagtgcga aatccatttt atttacgtag ctattattcg caattaaaac agcaggttga
     1321 tgccaaagtc accaaaaaag agttcgcgct ctggctactg gcattaggtg ctttattgtt
     1381 gctgttatgc atgccgttaa atgaaaaaag cacaattttt agcaccaatt ataccttgtc
     1441 attattgctg cccctgatga tgtggggagc gatgcgctat ggttataagc tgatttcgct
     1501 gctctgggcg gtcgtgttga tgatcagcat ccacagctat caaaattaca ttcccattta
     1561 tcctggctat accacgcagc tgaccataac ctcctccagt tatctggtat tctcttttat
     1621 tgtcaattat atggctgtac tggcaacccg tcagagagcg gtagtcagac gcattcagcg
     1681 gcttgcgtat gtggacccgg tggttcatct gccaaatgtt cgcgccctga atcgcgcgtt
     1741 gcgtgatgcc ccctggtctg cgctttgtta tttacgcatc cctggcatgg aaatgctggt
     1801 taagaactat ggcatcatgc tgcggattca atacaagcaa aaactttctc actggctgtc
     1861 acccttgctg gaaccgggtg aagatgttta tcagctttcg ggtaacgatc tcgcgctgcg
     1921 actgaataca gaatcgcacc aggagcgcat taccgcactg gatagccatc tcaagcaatt
     1981 tcgtttcttt tgggatggca tgccgatgca accgcagatt ggcgtcagtt actgctatgt
     2041 gcgctcgcca gtgaatcata tctacctgct gctgggagag ctaaatacgg tcgccgaact
     2101 ttccatcgtg accaacgccc cggaaaatat gcagcgtcgc ggggcaatgt atttgcaacg
     2161 cgaattgaaa gataaagtcg cgatgatgaa tcgactacag caggcgctgg aacacaacca
     2221 ttttttcctg atggcccagc cgattaccgg tatgcgtggt gatgtttacc atgaaattct
     2281 tctgcgcatg aaaggtgaga atgatgaact gatcagcccc gatagcttct tgccggtcgc
     2341 gcacgaattt ggtttatcgt cgagtatcga catgtgggtc attgagcata cgctgcaatt
     2401 tatggctgaa aacagagcga agatgcccgc tcaccgtttt gctattaatc tgtctccaac
     2461 ctcggtatgt caggctcgtt ttcctgttga agtcagtcag ttgctggcta aatatcagat
     2521 tgaagcgtgg caacttattt ttgaagtcac cgaaagtaat gctctgacca atgttaagca
     2581 ggcgcaaatc accttgcagc atcttcagga attaggctgc cagattgcga ttgatgattt
     2641 cggcaccggc tacgccagct atgcgcggct taaaaatgtg aatgccgatc tgcttaaaat
     2701 tgacggcagt tttatccgca atattgtgtc aaatagtctg gattatcaga tagtggcatc
     2761 gatttgccac ctggcgcgaa tgaagaaaat gctggtagtg gcagagtacg ttgaaaacga
     2821 agagatccgc gaggcggtgc tctctttggg gatcgattat atgcagggtt atcttattgg
     2881 taagccgcag ccgttaattg atacgctgaa tgaaatcgaa cccattcgcg aaagtgcctg
     2941 aataatgcgg gccgacattt ctcgtcggcc cgcaaagtat taagcggcga tttctggtgt
     3001 actttcttct tcaattttca accgccagcc agccacgcct tcccagtatt cttgctcctt
     3061 ttccagatca agcagtacca gcgcattctg actaaaccag tcatgcggga aacgcagtgt
     3121 ccagtgactg tcatcagtaa tcagcgtcaa tgttggcggt gtggtggttg cctgacgttg
     3181 attgttgagt aatacgccaa ggcgcaatag ctgtatcagt ggcaggaact gtttcttctt
     3241 aaacaaggta aagcgcggca gatcgtcgag cttaatcgct ttacggtgat agcgcaccag
     3301 tgtcgccatc atcagctgct gttcctgatt aaaacccggc aagtcactgt tttgcagaat
     3361 ataagcggag tggcgatgca aaccgctgtg gttgatattc aacccgacct catgcagcat
     3421 ggcggcccat cgcagtagcg cctccagttg cggatgcgcc agcttcggtt gctgttcccg
     3481 ccactgttcg tacatttgca tagtggtatc cagcacccgt cgggcctgtt cgctgtcgat
     3541 gtgatactgg ttggcgaggc tgctggcggt gcgactacgc acatcctgat gacggaaacg
     3601 tccttccatt tcatacagta cgccttcgcg taacgccccg tcagaaaggc gcagttcacg
     3661 gatggctaaa gcatcaaaca caccgcataa aatcgccagt cccggaacga agactgtttt
     3721 ccgctcttcg gaaagacccg gtaaactcag cgatgcgaaa ttacggtgac gtaaaatttc
     3781 ttttaccagt ttttccagac gttccggggt aattatcccg tctttctcgc ccatttccat
     3841 taacacttca tgggcggctt ttatggtacc ggaagcgccc attgcaacgt tccagccctg
     3901 aatacggaat tgccaggtta aagtttccag tttttgtgct gccgccatgc gagcgcgctg
     3961 aaaattctct ttattgatga ccccgccagg aaaataaagc tgggcaaagc tgacacaacc
     4021 catccggcgg ctttcaacga gaataggttc gaaattttca ccaatcacca gttccgtaga
     4081 tccgccgcca atatcaataa ccagtttgcg acctttttcc ggttgggtat gttccacgcc
     4141 cataaaaatc agacgggctt cttcattacc ggaaataatt tcaatcgggt agggaatgac
     4201 cttttccgcg cgtttcagaa agtcagtggc gttcagcgcc tgacgcagcg tatgggtacc
     4261 aactatacag acgctggcag gagaaaaccc ttgtagccgt tcggcaaaca gcgacagaca
     4321 gtttaaaccg cgcgtcattg cctcttcact caacatatta tctggcccca ggccgtccgc
     4381 cagatgcacc cgctgtttca ggcggccaat aatctgcatg gcaccatcta ccacacgggc
     4441 tatgaccatg tgaaaactgt ttgaaccaag atcgaccgca gcaaactcct gcggacgagg
     4501 ggatttatcg tgtattggca tagggttatt caggttgttc gagtgatttg atgtagtcat
     4561 aaatcgccaa ctgcgcccgt actttgcggc gattgccgcg gggaacgtag cgattactga
     4621 gttctttatc gatataacgt gctttgaccg tatcgctgaa caatatgtcg atgatgtcca
     4681 gtacccgctg cttcaggcgc ggatcgagca gcggcgtcgc cacttcaata cgataatcaa
     4741 tattgcgcgt catccagtcg gcggaagaaa ggtagacctt tttatcgccg ccattttcaa
     4801 aaatataaac ccggtcatgt tcaaggtaac ggtcaacaat actgatggca cgaatgttgt
     4861 cgctaatgcc ttccagattg gggatcagcg aacacattcc gcgaaccagc agattaaccg
     4921 gtacgccgga gctggaggcc gcatacagac gatcaaccag gcctttatcg acaaggttat
     4981 ttagcttcag ggtgatacca ctgggcagcc cttgctgcgc gttggcgatc tcgcggtcca
     5041 ccatttcata caataggcgg cgggagtttt gcggcgatac cattaaataa tcaaatgtca
     5101 ccggacggta tgggttttca ataaagttaa atacccgccg tacttcgttg gtgatgcgcg
     5161 catcggcggt cagcaacgaa tagtcagtat aaagacgcgc ggttttttcg ttaaagttcc
     5221 cggtcccgat gtgtgcataa cgcaccactt caccgttttc tttacgtgaa atcaggaaca
     5281 gtttggcgtg aattttcagc cccggcgcag agaagataac gtgcacgcct gcttcggtca
     5341 ggcgcttcgc ccagtgaatg ttggcttctt cgtcgaaacg cgcctgtaac tcaaccacca
     5401 cggtgacttt cttaccgtta tgtgcggcgt ggatcatcga gtcgatgatg cgtgaatctt
     5461 tcgccacgcg gtaaatgtta attttaatcg ccagtacgct cgggtcgaac gaagcctgac
     5521 gcagcagttc cagcacatgc tcaaaggtgt gataaggata atagagcaac acatcgcgtt
     5581 cgcgaatggc atcaaaacca ttgcggaact gggctttatc aaaccaaata tggcgtaaac
     5641 gcggcagtgg tttgttcacc agattggctt tgccgacatt ggggaaatta ataaagtctt
     5701 taaaattatg ataacgaccg ccggggacga tggagtcgta gcgggaaata gtcagttttt
     5761 cgcgtaacac ttcaaccagc gcattgggca tatcgcgctg ataaacaaaa cgcaccggct
     5821 cagcagttaa acgctgcttg agactggaag acatcaactc catcaggctg gcttccatct
     5881 catgcactaa atcgtattcg gcatcgcggg tcatcttcat tgaataggca ttcagcgcgt
     5941 cataatcaaa gaagcctttg aaaatatcat caaggcagta acgcagaatg ttatccagaa
     6001 gaatcatcgg cttgcgtcga cgcggcgctt ctggcggtaa attcacaaag cgcggcactt
     6061 tatctgatgg gatctccagc agcgcgtaac ggatggtatc gccacggata atttccaccg
     6121 ccagataggt gtaatcatct ttcaggaact gcactaagtc agtgtcagga ttgattaaaa
     6181 tcggcgtaat gtgctgacgc agatactgct taaaataatg acgcagccag ttttgttgat
     6241 tgacggagag ctggcgttca ttaatcagga agatctggtt gcgcgccatc tccagcaata
     6301 gctcgttgta gaggccgtcg aattcctgat cggctttcag cacccgggac tgaattttgc
     6361 ccagtaaatg gcgggaatga gagttggagc cttgttcttc gctaataatg atgcgtcgct
     6421 tcagttcagc gaagcggact ttatagaact catcaaggtt attggaatag atccccagga
     6481 aacgcatcct ttcaatcagc gggttagatt tgtccgccgc ttcctgaagc acgcgttcat
     6541 tgaacgataa ccaactgagc tctttttcga tgtatagctt ttcctgaccc attaccactt
     6601 ttactccgtt ttattcacgg gacactgcct ggatattatg gcgagcaata ttggcagatg
     6661 tccaactatg ccagaaaagg gggaaaaaaa ctgctggagc ttgcgattta caggtgaatt
     6721 gaaaaacgcc agcggcagag ctggcgcttt aattacgggg gtattactcg tcggcagcgt
     6781 agccctgcgg cggcagacgt tgaccatcca gccacgcggc gttttcgtgc attttcagac
     6841 gaccatcggc aaaccagcta atcaccagtg gataaatggc gtgttcctgg gtttgcacgc
     6901 gggcggtgat gtcatcttcc gaatcaccag caaataccgg gactttcgcc tgtaaaataa
     6961 ccgggccacc gtccagttca tcggtgacga aatgcaccga tgtaccgtgc tcttcatcgc
     7021 cattttccag cgcctgacga tgggtgtgta atccgggata tttcggcagc agagaagggt
     7081 gaatgttcag caaacgcccg gcatagtggg agacaaacgc cgggctgaga atgcgcataa
     7141 aaccagccag cacgaccaca tcgggtgcgt acatgtcgat ttcatgaatc aactcccggt
     7201 cataggcttc acgactgtca aacgcgctgg cgatgagcgt atgcgttgca atacccgcct
     7261 ggcgggcgcg ttcaaggccg aacgcgtcgg ccttattgct gaaaactgcc cgtacggtgc
     7321 ctttaatttt gttggtttta caggcgtcaa taattgcctg taaattactt ccgttgccgg
     7381 aaataagcac cacaatattc attattcgat aaccacgcgt tgttcggaat cagaggcttt
     7441 gatgataccg attttccacg cgttttcacc gttggcattg agcagggcga gggctttgtc
     7501 cacttccgga gcaggcaggg caataatcat cccgacgccg cagttgaagg tgcgatacat
     7561 ttcatggtgc tcaacgttac ctgccgtttg cagccagttg aacacttccg gccactgcca
     7621 ggaagattca tcaatcactg cctgagtatt atctggcaat acgcgcggaa tgttttccca
     7681 gaagccgccg ccggtcaggt gcgcaatggc atgcacatcg accttttcaa tcaactccag
     7741 cactgacttc acgtaaatgc gggtcggtgc cagcagatga tcggctaatg gcttaccatc
     7801 aagttcggtg gtttgcggat cacaaccgct gacttcaaga attttgcgca ccagcgaata
     7861 gccgttcgag tgtggaccgc tggaaccgag tgcaatcagc acatcgccgt cgctgacttt
     7921 agagccgtcg atgatttctg atttttctac cacgccaacg cagaaacccg cgacatcgta
     7981 atcctcaccg tgatacatcc ccggcatttc tgccgtttcg ccacccacca gtgaacagcc
     8041 tgattgcaga caaccttccg caatgccgct gatcaccgct gaagcggtat caacatccag
     8101 ttttccggtt gcgtaatagt cgaggaaaaa cagcggctct gcaccttgca ccaccaggtc
     8161 attaacgcac atggcgacca gatcaatacc aatggtgtcg tgacgtttta agtccattgc
     8221 cagacgcagc ttggtaccta cgccgtcagt gccagaaacc agcacgggtt cacgatattt
     8281 ttgcggcaat gcacacagcg caccgaagcc gcccagaccg cccatcactt ccggacgacg
     8341 cgttttcttc actacgcctt tgattcttcc aaccagagca ttacccgcgt caatatcaac
     8401 accggcatct ttgtagctaa gagaggtttt atcggtcact gcttgggtcc ccacgcgtta
     8461 cttgcggtag aaaaataaaa ttcggcgcaa ttctaacagg gaaagcaaac gtttgcgaga
     8521 ctgctttaca caaccttttt gcacgtcttt tccccaggcg cgcggcgaaa gaagacttgt
     8581 gccagggtaa aggttagttt tcggatggaa taatcttctt tcataaccat ctgaatataa
     8641 aataacttta tctcaaaccg ttatcatttt gactaaagtc aacgaaaaga atattgccgc
     8701 cttgaagaaa ggaggtataa tccgtcgatt ttttttgtgg ctgcccctca aaggagaaag
     8761 agtatgaaga tcgtggaagt caaacaccca ctcgtcaaac acaagctggg actgatgcgt
     8821 gagcaagata tcagcaccaa gcgctttcgc gaactcgctt ccgaagtggg tagcctgctg
     8881 acttacgaag cgaccgccga cctcgaaacg gaaaaagtaa ctatcgaagg ctggaacggc
     8941 ccggtagaaa tcgaccagat caaaggtaag aaaattaccg ttgtgccaat tctgcgtgcg
     9001 ggtcttggta tgatggacgg tgtgctggaa aacgttccga gcgcgcgcat cagcgttgtc
     9061 ggtatgtacc gtaatgaaga aacgctggag ccggtaccgt acttccagaa actggtttct
     9121 aacatcgatg agcgtatggc gctgatcgtt gacccaatgc tggcaaccgg tggttccgtt
     9181 atcgcgacca tcgacctgct gaaaaaagcg ggctgcagca gcatcaaagt tctggtgctg
     9241 gtagctgcgc cagaaggtat cgctgcgctg gaaaaagcgc acccggacgt cgaactgtat
     9301 accgcatcga ttgatcaggg actgaacgag cacggataca ttattccggg cctcggcgat
     9361 gccggtgaca aaatctttgg tacgaaataa agaataaaaa taattaaagc cgactttaag
     9421 agtcggcttt tttttgagta aagcgcctat aacacataat acagaggata atactatgac
     9481 gcgccgtgct atcggggtga gtgaaagacc gccactttta cagacaatcc cgcttagttt
     9541 gcaacatttg ttcgccatgt ttggtgcaac cgtcctggtg cccgtcttat ttcatattaa
     9601 cccggcgact gtactgttat ttaacggtat tggaacgctg ctgtatctct tcatctgtaa
     9661 agggaaaatt ccggcttatc ttggttccag ctttgccttt atttcaccgg tattgttact
     9721 gttgccgtta gggtatgaag tcgcgctggg cggctttatt atgtgcggcg tgctgttctg
     9781 cctggtttct tttatcgtga agaaagcggg gaccggctgg ctggacgtgc tgtttcgacc
     9841 tgcggcaatg ggcgcaatcg ttgccgtcat cggtctggag ctggcgggcg tagctgccgg
     9901 tatggcgggt ttactcccgg ctgaagggca aacgccagac tccaaaacca tcatcatctc
     9961 tattaccacc ctggcggtca cggttttagg ttccgtgctg tttcgtggtt tcctggcaat
    10021 tatcccgatt ttaattggcg tgctggtggg gtacgcgctc tctttcgcaa tgggaattgt
    10081 cgataccacg ccgattatta atgctcactg gtttgcgctg ccaaccctct atacgccgcg
    10141 cttcgagtgg tttgccattc tgactattct gccagcggcg ttagtggtta ttgccgaaca
    10201 cgtagggcac ctggtagtaa cggctaatat cgtcaaaaaa gatctgctgc gcgatccagg
    10261 tctgcaccgt tcgatgtttg ctaatggctt gtcgaccgtg atttccggct tctttggctc
    10321 tacgccaaat actacttacg gagaaaacat tggcgtgatg gcgatcaccc gtgtttacag
    10381 tacctgggtt atcggcgggg cggcgatttt cgctatcctg ctttcctgcg tcggtaaact
    10441 ggctgccgct atccagatga tcccattgcc ggtgatgggc ggcgtttcgc tgctgcttta
    10501 tggtgtcatc ggtgcttccg gtattcgtgt tttgatcgaa tcgaaagtgg attacaacaa
    10561 agcacagaac ctgatcctga cttccgtgat tttgatcatc ggcgtcagtg gcgcgaaggt
    10621 aaacatcggc gcggcggagt taaaaggtat ggcgctggcg accatcgtcg gtatcggctt
    10681 aagtttgatc ttcaaactga tcagtgtgct gcgccctgaa gaagtggtgc tggacgcaga
    10741 agacgcggat ataacagaca aataatgtac cgaccgggca gtgttgctgc ccggttcaaa
    10801 catcatggga ttctgtggta aacttctcgc gattttgtga aatcctggtt gaggtatctc
    10861 tgaacacacc ggcacagctc tctttgccac tttatcttcc tgacgacgaa acctttgcaa
    10921 gtttctggcc gggggataac tcctctttac tggccgcgct gcaaaacgtg ctgcgtcagg
    10981 aacatagcgg ttacatctat ctctgggcac gcgaaggcgc ggggcgcagc catctgctgc
    11041 acgcggcttg cgcggaattg tcgcagcgtg gcgatgcggt gggctatgtc ccgctggata
    11101 aacgcacctg gtttgttccg gaagtgctcg acggtatgga gcatttgtcg ctggtctgta
    11161 tcgacaacat tgagtgtatt gcaggcgatg agttgtggga gatggcgatt ttcgatctct
    11221 acaatcgaat tctggaatcg ggcaaaacac ggttgttgat caccggcgat cgtccaccgc
    11281 ggcagttgaa tctgggatta ccggatctcg cgtcgcgact cgactggggg cagatctaca
    11341 aattgcagcc actttctgat gaagataagt tgcaggcgct acagttacgc gcgcgtttgc
    11401 gtggttttga actgccggaa gatgtggggc gtttcttgct gaagcggctc gacagagaaa
    11461 tgcgcacgct atttatgacg ttggatcagt tggatcgtgc gtcgattacc gcgcaacgta
    11521 agctgaccat tccgtttgtg aaagaaattc tgaagttgta gataaggtgt ttattgtcgg
    11581 atgcggcgcg aacgccttat ccgaactacg cgaagttaat ccatagtatt cgtaggccgg
    11641 ataagacgtg gcaagcgtcg catccggcaa tgtgcttcaa ctagcgatgg agcacatctt
    11701 aacccacgat ttccagtacc tgctccggtg gacgaccaat ccgcgctttg ccattcgcga
    11761 ccacaatcgg gcgctccatc agcttcggat tatccaccat tgcctgaatc agcgcctctt
    11821 cgctaagcga actgtcagcc aggttcagtt ctttataaag atcctctttc tggcgcatca
    11881 attcacgggc gctattcatc cccagtattt tcagcaaatc gcgcagcgtt gccgcatcgg
    11941 cgggtgtctc aaggtagagc accacttctg gctccacgcc gttttctttc agcaggttca
    12001 gcgtttcccg gctctttgaa cagcgtgggt tatggtagat ttttacctgt ttggtcattg
    12061 ttcttccttt aatgcgaatt acatcttggt ataaggctta aagcgttcct gcagctggcg
    12121 caactggtcg atgcgcgcat cgtaacgcgc ttgttgcagg ctgcctaatt tcacctgcga
    12181 actggcgcta ctcaacagcg aaatggcctg atcgagtcgt ccggcgagcg cataaccttc
    12241 tgctcgcgca gccagctcct gatcgcggtt atttagcgcg gcttccgcct gtgccagcaa
    12301 atcccagccg ttgctgtcat ctttattatt aaaggtgtag cgattcagaa tattggccgc
    12361 ttcttgtggt tgaccgcctt gcaaataagc gttcgccagg ttgagctgca acaccggatt
    12421 ggtgcgtaaa tcgcgggcat ttttcagacg attgatcgcc tcattggctt tgttttgccc
    12481 aagatcgata tcagtagcca gatcgagata ccatgcgttg ccaggttctg ccgccagtaa
    12541 cggttgcagc gttttacgcg cctcgtcgta tttattggct tccatcgcct gtaaagcacg
    12601 accatattgt gctgctcgtt gctgacgaac gtttcctttc gcccattcat ccagcaaatc
    12661 actggtgagc tggttacgtc cggaattata catccccagt gtgcgcgctt tcgccagata
    12721 gaaatcttcc gacgactgca ccaccatcgg gcgcatctga ttagcacggt tgcgggcatc
    12781 tgccagacga ctttccggca acgggtgagt caataaaatt tccggcgggc gcgaggagta
    12841 acgcgcctga tcgagtaatt tttcgaggaa ggttggcatc gcctgcggat cgaatcccga
    12901 gcgttgcagc acctgaatac caatgcggtc cgcttcctgt tcattttgct gggtgaaact
    12961 gatcatcccc tgacgcgttc ccgccagtgt accggtcagc gccgccatcc ccgcctgcgg
    13021 actggccatc gccagtaaaa tagaacctaa cgcgccgacc caggtcagcg gcgcgctgcg
    13081 ctgctgatct tccatcgctc gcgccaggtg acgttgggtg acgtgggaga tttcgtgcgc
    13141 cataactgaa gccagttgac tttcgttatc ggaataacgg aacagggcag agtgcagcac
    13201 cacgttgccg ccaaagaaag caaaggcgtt aatttcgtcg ttgttgatca gaaaaaaatg
    13261 aaacggtgtc ttaaccgaat tggcattcga aaccagacgc atccccagcg aattaatata
    13321 ttgcgttaac agcgggtcat taattaacgg cgcgctgccg cgtagctggc ggacataata
    13381 gtcgcccatc tgcatttcct gaccaatgga aagcgtgctt cctgcggagg ttcccatatc
    13441 cggcaaggtg tctgcgctgt cggcaaacgc cggggctacc tgaccaatgg tcatagcagc
    13501 aatgagggtt gcaaccaggt tttttttcaa ctgcctgaac ataacctcta tcctgtattt
    13561 ctggagatag tcatttgacc gatactgtga aatatcgttc ccaccgcgcc gcctttgagt
    13621 gtaacggcga agattagccc actcaaatga cttttcagtt tcctgaatcc gtcataaaaa
    13681 gcgaagtctt ttttgtgaca tttcgataca attgcggatc gcaatcccgc tcttgaggtt
    13741 cagggaaggt ctttatgctc gaaatgttga tgcaatggta tcgccgccgt tttagcgacc
    13801 cggaagcgat tgccttgctg gttattttag ttgccggatt tggcattatc tttttcttta
    13861 gtggcctgct tgctccgttg ctggtggcta ttgtgctggc ctatttgctg gaatggccaa
    13921 ccgtgcgtct gcaatctatt ggctgctccc gccgctgggc gacgtcgatt gtattggtgg
    13981 ttttcgtcgg tatattgcta ctgatggcgt tcgtggtact gcctatcgcc tggcaacagg
    14041 gcatctactt aatccgcgat atgccgggga tgctcaataa gctttctgac tttgccgcca
    14101 cgttgccgcg ccgctatccg gcgttaatgg acgcgggcat tattgatgca atggccgaaa
    14161 atatgcgcag tcggatgctg accatgggcg attcggtggt gaaaatttcc ctcgcctcgc
    14221 tggtcggttt gctgaccata gccgtctatc tggtgctggt gccattgatg gtcttcttcc
    14281 tgctgaaaga caaagagcag atgctgaacg ccgttcgccg ggtgctgccg cgtaaccgtg
    14341 ggctggcagg acaggtgtgg aaggagatga atcaacaaat caccaactat atccgcggca
    14401 aagtgctgga gatgatcgtg gtggggatcg ccacctggct ggggttcttg ctcttcgggc
    14461 tgaactattc gctgctgctg gcagtgctgg tcggcttctc ggttcttatt ccgtacattg
    14521 gcgcatttgt ggtgaccatt ccggtggttg gcgtggcgct attccagttt ggcgcaggta
    14581 ctgaattctg gagctgcttc gcggtgtatc tgattattca ggcgctggac ggcaacctgt
    14641 tagtgccggt gttgttctcc gaagcggtta acctgcatcc gctggtgatt attttatcgg
    14701 tggtgatctt cggtggtttg tggggattct ggggcgtatt cttcgccatt ccgttggcga
    14761 cgctgatcaa agccgtgatt catgcctggc ccgatgggca aatcgcgcaa gaataatctt
    14821 cagcccgacg aactgtttcg ccgggctgat ttttcagggt tcctgacgta aataaatagc
    14881 ccgataacac atactcacca gcaccgcacc gccgataata ttacccagca tcaccgggag
    14941 cagattggcg gtaataaaat ggctgaccgt cagtgccgga aaattgtctg cgctactgtg
    15001 cgccagctgc cagaaggggg gaggggcgaa atggcgaatg gcaatggcga acggaatcac
    15061 aaacaaattg gcgatacagt gctcaaagcc actggcgaca aacagggtga tgggcaaaat
    15121 catggcgacg attttgtcgc ataacgaacg cccgcaataa ctcatccaca gcgccaggca
    15181 aaccatcaga ttgcacataa tgccgaggct gacagattca gtaaatgtat gatgcatttt
    15241 gccctcggcg cagtgtaaaa ccgcgactcc ccacatcgcg ttttcactca tcaccagccc
    15301 ggaaaaccag attaacaaac tgaaacaggc aatacctgcc agattaccgc aggccaccag
    15361 aagtgcgtta atcagccaag ttcgccaact aataacgccc cgactttttg ccatcaccgt
    15421 cattaccgac gaggtgaaca ggctggtgcc gcaaaccgcc agcaaaataa agccgagtgt
    15481 aaagcaaagg ccgcccacca gatgggttaa tgcctgtgaa gacggggcat cggcgataac
    15541 ggaaaggtaa aaagtaaatc cgatcgccat aaacacgcca gcggacatcg ccattaaaaa
    15601 gaccgacact ttactgcggg caattttatg ggcggcaatc cgttcagcga ttgccgcttt
    15661 tctggcgctc aactgcaagt cgaaagagag tttgtttctc atgcatactc ctgcaaaagc
    15721 agattacaac acctcgcgaa ccgagatccc cagccgctgc attcgtgaca gcagcgtggt
    15781 gcgcttcatc cctaatcgcg tcgctgcgcc acggggcccg gcaacaatgc cattggtttc
    15841 tcgcaatacc tgaacaatgc gctgacgttc ttcttcgtca ttctctggcg tcgtcgggtg
    15901 cagtaactgc gccattgaac tgcgaagcgc tgaatcttca tttagcgtcg gcagtaaacg
    15961 gctttgtcgg acatttagat gtaaattcag actgttacca cgagtcaaca gtaccgcccg
    16021 ctcaatcacg ttttccagct cgcgcacgtt gcccggccaa tcccacgaca tcaactggcg
    16081 tagtgcctcg gtcgggatgg cgtcaattgc gcgattcata tggcgcgcca ttttttgcgt
    16141 gaaatgtttt gctaaaagag ggatatcttc cggacggtcg cgtagcggcg gcaattccag
    16201 tgggaagaca ttcaggcgat aaaagagatc gctgcgaaac tggcgatctt caaccatttg
    16261 ccacaaatca cggttggtgg cggcaatgac tctgacattc accgggatcg ttctactccc
    16321 gccgagacgc tcaatctccc gctcctgcaa tacgcgcagc agtttaggct gaagttctaa
    16381 cggcagatcg ccaatttcat cgagaaacaa cgtgccgcca tcggcaattt caaaacgacc
    16441 acgatgggta ttaatcgcac cagtaaacgc ccctttgtca tgaccgaata actcactttc
    16501 cagaagactg gcggggatgg cagcgcagtt gattttgacc agcggcttgt cgcgtcgcgg
    16561 gctaagttga tggatcgctc tggcgatcac ctctttgcca gttccggttt caccacaaat
    16621 caacaccgta ctgtcgctct tcgccacaat atctacctgc tggagcaggt cttccattgc
    16681 ctggctttga tagataatgt caccgatgcc cagattcgaa aggagctgct cgctaagctg
    16741 gtggttttct tgctgcaaac tttcctgcaa atcggtcatg ctacgccagg catcggcatt
    16801 gccaacggca atagcgatgc gatcggctat gtgttgtagt agctggcagt tttcctcact
    16861 aaagagagtg gaagaggtat gcgccagcaa caatgcaccc ggtgtatggt tgccaaaggt
    16921 aagcggtata aggagcgcag attcgcagcc gttagatgca agtaagagta ataacgggtc
    16981 gcgttgccag agaaacagat catctgcacg gtgcgtcaag gtcggttgtc gggtttgtag
    17041 cgtttgtgtc agcaatacac tttcgccagg catacagcgt ggcagacacg cacaatgtga
    17101 ggcagaaaga tcgctgcacc acaggctgaa cttctcgttc tttcgatgat cgcccagtac
    17161 catactgact gaagccagac cgaaaaaatg atggatctca cgagcgacgt cagcgatcag
    17221 atcgtcgaga tcaagatgtg acagcactgc attagtaata tcaaccagta cccgatgatg
    17281 atcgcgatct ttctccagca aacgcagcgc cacctgctgt tcttcatcat tgagccatga
    17341 ttgcagaacc ggggtgatta tccgcgccag ccagttaaac agtgtgcaat cctgggaagt
    17401 aaaacgactg ccgtgggtgc gaataaagcg tagctccgcc attccactac tgccgagaag
    17461 gacggcgtga cgcgaataat cgaccatctc gccctgatac tctgttgttg ccgtcacatc
    17521 gctgccatca tcatggtagc ggtaatagaa gttgcttttg agaacatgca gttcaataag
    17581 ttgtaccggg ctgaacggcg gcggcagcgg gatgaaggcg cgtaataaag acgccttgcc
    17641 gtgtttctgt gctaaccgct ccgcgagcat tccgtttacc gcttcaattg ttattccttg
    17701 tggcggggca aacatcgcct cgtctgacat agccatcaac agtccttatt aatgagaaat
    17761 ccttctcacg caatttttct ggccatcaga tagatggccg gttcctgcac aatttcatcc
    17821 aacagatgaa tgaattgaat gctacgcgcc tgccacacag acgtcgcgtc atccgccagt
    17881 ggcgcgaatg cccgggtcaa cagggcggtg tggctggcgt caataacaat ctcaccaaaa
    17941 gtcatcaccc ccagcatctt acgtcgggct tgctcctctt cgaccagtgc aagccaatct
    18001 tcgtattccg tcagtgggca gcggaaggcg acattcagac aatcaatcac gccaacgtga
    18061 tggccgatag ctagcgagta atacattacc tgagagctgt gttccggcat ctcgtcgcta
    18121 ctggcgacaa acttttttcg cagcgtccag aaaacaattt ccccgcactc ttcagtcatg
    18181 taacccccgg agtacgcgaa agagttgctg aacgatacta ttgagacgtg gatcgtcggc
    18241 atcgcgcaac caggtgttaa cccgatttcc tgtaggatcg tcgcttaaat ggcgcaggag
    18301 ccgatcgcaa atttctcgcc cctgacgata gcccgccagc cgccgcgctt ctcgctcaat
    18361 ggcgatacgc tgtgatggcg ggatctgcgg ccacaacggt tgcatagtca ccccggtggg
    18421 atcgcgataa tccacagcgt gaatcttctg ttgcagcaaa ccgagcgcca cggcgaaacc
    18481 gtgaatggtg gcggccggtg ttggcgggca gccggggatc caaacatcaa tggggacaat
    18541 ggtgtcgcta ccgccccaga cgctgtagag atcgtggaaa ataccgccgc cgacaccgca
    18601 cgcgccgtag gaaacacaaa ttttatgatc gggggcagac tcatacgccc gaagtgcagg
    18661 catacgcatc gcccgggtga ctgcgccagt aaataacaaa atatcggcgt gacgcggtga
    18721 tgaaacaacc ttaatgccaa aacgttctgc gtcgaatact ggtgtaatgg cagcaaaaat
    18781 ttcgatttca caggcgttgc agccgccgca atcgacgcga taaacgtaag ccgagcgacg
    18841 gatatcctgt agcaaatgcc gcttcatctt ttgcgtttgc tcgtccagcg tgatgggctg
    18901 gctgacatgt tgtgtaagca ctggactcat agctgctcct tagccaccag cagtacatct
    18961 gtatcgtcgt tgatcagcgt cgcgcgttgt ttgcattccg ggcagacgct cgcttgcgcc
    19021 cacaacattt cgcggttttg tggcgcattt tgttgctgtg ctaacaattc agcagccagt
    19081 gcgatggttt tttgcggggc aaacgggcgt tcgcaacggc tgcaacgttg tagatggaac
    19141 gtcgcgcggg tatagagatc ggctttattg gtgacggtca gttcaaagtt attggtaagc
    19201 tggatggctc tggtcgggca cacttcttca caacgtccgc agtaaataca acgccccaga
    19261 tagagctgcc aggtgcgcga attttgctgg tcgtcggtct ggatagtcag cgcatttgcc
    19321 ggacaagcac aggcgcaggc accgcaggca atacattggc tgggcatcag gtccggtttt
    19381 ccgcgaaagc cagggctgac ctccagtggc gcgaagggat atttcaccgt cgcggttccg
    19441 gcgcgcataa tagttttcag taacttcagc atcttctgtc cttacttcag cggcgaacgg
    19501 ttacgatcaa tgccgtagcg ttcgatctct ttatacggca cggtttttga ctggcgcttg
    19561 cgcacatcta ccagcgtcac acggtcggta caggagtagc agggatcaag gctaccgata
    19621 atcagcggtg cgtcagaaac ggtattgccg cgcagcatgt aacgcaacac cggccagttg
    19681 gcgtaggtgg cggcacggca gcgccagcgg aacaattttt ggttatcacc gagcatgctc
    19741 cagtgcacgt cttcaccgcg tggcgcttca acaaagccca gcgcgaatgc gtgaggttta
    19801 tagctaaagc cttcggtcag cagtggggta tccggcatgt tgtcgagggc aaattccagc
    19861 attgccagcg aatcaaacgt ctctttgaca cggaccatca cgcgggagaa aacatcgccg
    19921 ccggtaaagg taaacagtgt ttttggaata ttgccgtagt cggcgtaggg gtgatcaaag
    19981 cgcaaatcac gggcgatttg tcggtcgaga atgccaatgc cctgagtgcg ttgttccata
    20041 ttcggcgtag caagcagcat ctctaccagc tccgacacgt cggcgcgcat ctcgcgcacc
    20101 agtttcagcg tttgcagacg ttgctctttg agaatatcgc ggcgaacacc accaatcaga
    20161 ttcagaccgt aggttttacg cgacccgatc agcaattccg ccatcgtcat cgacttttcc
    20221 cgcacgcgga aaaattgcat aaagccggta tcaaaaccaa cgaaatggca ggagaggcca
    20281 aggttaagca aatgactgtg tagccgttcg acttccagca gaatcgagcg aatagtatgt
    20341 gctcgttgcg gcacctcaat ccccagtgca ttttcaaccg aattggtata ggccacactg
    20401 tgggcaaaac cgcaaatccc acacacgcgg tccgataaga aggtcacttc gttgtagccc
    20461 atccgcgttt ctgccagttt ctccatgccg cgatggacat aaaacaggcg gtaatcagca
    20521 tcgacaattt gctcgccatc cacaaacaag cggaagtgac ccggttcatc ggaggtgata
    20581 tgcagcgggc cgacagggat cacccgcgca tcgctgttgc cctcattgat aaacggatac
    20641 gtttcggaat cagtcgtcgg ttcagggcgc agtcgataat ccatcgcatc tttgcgcagc
    20701 ggatgcatat cttccggcca gtcatcgggc aacaccaggc gacgctgatc cggcaggcca
    20761 accggaatca gcccgtacat atcgcgaatt tctcgctcgc cccagaccgc ggcagggacg
    20821 cgcggtgtga ctgacggaaa ctcccgactg tcggcatcga ccagcgcctt caccacaatc
    20881 cagcattttt cggccccttc cattgaaagg gcataataaa ccgcgtaatg accgttaagt
    20941 gtccgctcgt cgttgccaaa caggaccgga agccagccat catgttgata ataaagatac
    21001 tgtacaacgt caggcagcag attgattttc accgtaatgg tgacctgttc aggcgtttgt
    21061 cgctcttcat ccagcaccgc gccggggaac tgcgttttca gggcggcgag aatcgcttcg
    21121 ccacgatttg acgatgaatt aacgttcact gtgtttctcc gaaacagatg cggtgcctga
    21181 aggcaaaaaa tcatgccagg tgctacgttg tgcaggcaga tcgtgcgtcc ctgagaggac
    21241 tatagtggaa gcgcccgcca ggatcctgat gacaggttgt ggaatatgcg ttcccatcgc
    21301 cagcatcatg accagcagaa tcaccattgg cgaggtggtc aaccagccga gatcaccccg
    21361 gttaacggcc tgcggcggtt tcgccattaa cacccgcgca gccatccgta ccaggcccgc
    21421 cagcaccagc gttaacagca ataacagcag gacgataatc agcaggtgat tacgtgccag
    21481 tccggcggta atggtcataa attcgctaag aaaaatgttg aagggcggca tccctgccag
    21541 cgccagcgca ccgccgccaa acagcacggc ggtaaatggc atgattttga gcatcccaca
    21601 gacgacgttg agatcgcgcg tgccgtactt gagcagtaca ttgccggaac cgcagaacag
    21661 cagcgttttt gccagactgt ggtttaagat gtgcagcagc gcggcaaaaa ttcccagcgg
    21721 cccgccaatg cctagctcca ccgcgaccag ccccatgttc tccacgctgg agtacgccag
    21781 cagacgctta atgtcccgct gtaccagaat gaaaaatgcc gccacggcaa ccgacaacat
    21841 gccgaagatg agcaacaacc ggttggggaa atcgctgccg atggcttggc aaataatgat
    21901 gtaatagcga atcagcacca acagcgcgca gttcagcaat acggcggaga gcagggcgct
    21961 gaccggactc ggcgcttcac tgtgagcatc cggcagccag gcgtgcatgg gaaatagccc
    22021 ggttttggta ccaaagccaa ttagcaaaaa cacaaaggcc aacagcatta atgttgggtc
    22081 aagcaaggac gattgcttaa gaacctcgct ccagaatatc gccatttctg cctgcggcat
    22141 aacgctggcg gcgttggcgt ataccagcac ggtaccgaac agaccaaaag cgacaccaac
    22201 agtacaaata atgatgtact tccatgcagc ttccagcgat gaacgctgac cgtaaatgcc
    22261 taccagaaac gccgagctta aggtggtggc ttcgatcgcc gcccacatca caatcaggtt
    22321 attgctggta acaaccagca gcatggtgaa caaaaacaga tggaagaaac cgtagtaatc
    22381 gcacagcgta acgggtgaaa gctcgccgtg tgccacttca tgacgcatgt agccaatcga
    22441 gtaaataccg gtgagaaagc caatcacacc aagaatggcg aggaacaaac cgcccagacc
    22501 atcaatatga agccacagtc ccgcagcgaa tatttctcct gcatcagcgg cagtttggac
    22561 cacccagagt gccagaatca gcagcagtgt gatccctaag ctatgtaata cggtcaccgt
    22621 gcgagtcgca gaaagtctcc gtttccggca ggcaaaacag agcagcgaaa aaagcagcgg
    22681 cgtgagcagg agtaaagcga acatcacaga ataactcatc tcattatccc ttcagcgcgg
    22741 tcaagttgtt cacgtccagc gtgccgtggg tacgccatat ttttcttgcc agtaacacca
    22801 tcacaatgac ggcgaagatg gcgtcggtag cgatacctat ttccaccagt tccggtgctc
    22861 gccaggcaag aagcgccagc accagatggg agccgttttc catcaggcag taaccaaaaa
    22921 tttgccgcag gatattgcgc tggctgacaa tgcacagcag gccaagcaga aaatgaccta
    22981 acgctaccgc cagcgccggt ttcagcccgg tagccatcgg tagcttcacg ggctgaacga
    23041 caaatgcgca aagcaggaca attaacgccg cgagcagtgc catcattgcc ggaccgaata
    23101 acgctttttc cgggatgttc tggggaatat ttcgtgcagc gtaagtcatg attaacggta
    23161 ccagcagcac tttggtgata aaggcgctgg cggaccagat cagcagttgc tctgcggcga
    23221 acaggcacga gagagtggcg aaaatagaca ccagcaccag tgactggcag gcgtaaaatc
    23281 cgcatgacag gcgatagctt ttgacgctaa tcacaaacag cgatgtcagc atcatcagtc
    23341 ccgccagatt atttacgatc atagaaccgg tcattcatca tctccttact gcaaccaggt
    23401 cgcggcgatt acgctggaaa tcagcgacat cacaatcagt acaatcaaca ccaggcgcat
    23461 tgatcctggc agcggtgcgg catcggcgac ggcctcgctc ggtttgccag gcacaacgcg
    23521 accaaaccag cgaataaacc aggcgaaact ggcgaccgat tcaatcatca gaagaatcat
    23581 ggcgggcagc aggatccagt actccactga caacgcaaaa ccggcagcaa acagcgggaa
    23641 tttactgaag aagccgttga acggcggcac gccggtaatc gccagcgctg ccacgcagaa
    23701 acccacgcct ggcaacggca gggtgtgcaa tacgccacgc agacgcggca acaagcgcgt
    23761 gccgcagctg taactcagcg cacctgctac aaggaaaaac aggcttttag cgaacgcgtg
    23821 gttgacgatg taggcgatgc tgccctccag cgccagccgc gagccgaaga tggagagcga
    23881 caagccgaag aacatccagc caagttgagt gatggtcgac caggctagca accgcttcat
    23941 atcctgctgt ggcaaataca tcagaaagcc ataaagaatg gtgaccagtg ccatgaccat
    24001 gccaacgccg ccaatcacat gcgggatatt gccgccgtcg ataatagcgc gggcaaaaat
    24061 gtaaacgccc actttcacca tcgatgcggc gtggagatag gcgctgatcg gtgttggcgc
    24121 ttccattgcg tccggtagcc acgcttgcat cggtagctgg gccgatttcc cccacgcggc
    24181 aaacaggatg ccgccataaa ccagataacg tgcgtcgccg tgtaactcgc tcatcgcgct
    24241 aagcgcaaac gttccggtct gcaaaaacag cgtggcggcg gcaagataca accccaacga
    24301 gccgatatga gtgataagta acgcttttag tgctgaacgc tgcgctttat cgctctggta
    24361 ataactgatc aacgcccagg agcagccgcc tgtaatttca aaaaacaaca actgaccgag
    24421 cagcgtcgag gagagtacca gtcccgccat cgcgccgata aacaccagta aaaatgcgta
    24481 ataacgattc gtgccgttat gcgggtgttc gcgattttta tccgtcagat aacccgtgga
    24541 gtagatcgtg accagcaaac cgagaaacac caccacaaac agaatcagcg tactcacgcg
    24601 atcaatgacc aggccaaaca acgccacatc ccccacgttg accaacgtca acgtgacggc
    24661 aactttatcg gcctgataaa acgcggagat cagtgacaac atgcacagcg tggtcagcgc
    24721 ggcgaacaaa accccccatt cggcggcccg acgttgtggc gaaaacgaaa cgaccagtgc
    24781 gccgataaaa ggcagcaata acgtcgtcag agcaagattt tccatattcc gtcagtgctc
    24841 cttacagacc ggttaaccag aagacccatg caagcgcagc aaggctgaag ccaagccagg
    24901 tcacatggtg aatgagtaaa aaacgcccgc gtgccagcgt gttttctgcg attgaggcca
    24961 gtacaaaaat cagcaaaacc ttgagcagcg taacgacaag tgaagtcagc aggcaggcga
    25021 gagaaagttc ttgcgcgcgc ccaaagggca gaaacagggc cacaaacagt gatgccatca
    25081 cgacctgttt cagccccagc ccccatttcg ctagcgccag cccggcaccg gaatattcgg
    25141 tcagcgggcc ttcctgtaat tcctgttctg cttcagcaac atcaaaggga atttttccca
    25201 tctcaatgaa gcaggcaaaa ccacaggcca gtaacgccag tacggtggtt agcggcgagt
    25261 tccagcccat cgccagcgta ttgctgatca tctcgatatg cgtggaacct gctatcagcg
    25321 ccaataccag cagtgagaga ataagcattg gttcgaccag aatgccgagc gtcaactcgc
    25381 gactggcacc gactcccgca aacggacttc cggtatccag cccggaaaga gcaaagaaaa
    25441 aacgaaacag ggcaagaaga tagataaggg tgatcagatc gccgccgccc gcaaaagggg
    25501 aaacggtaat aaacagtggt aaggccatcg ccagcaccag catgctgctg attaataccc
    25561 acggcatcag gcggaacatc agacctgaag atgtcggcgc aacttcctgg cgtttaaaca
    25621 gtttgtggat atcgcgataa tcctgccaga tccccggccc gcggcgggag tgcatacgcg
    25681 cgcgtatctg ccgggaaata cccgtaaaaa gtggggttag catcagcaga atcacggcct
    25741 gtgctaacgc aaaaatgacc agatatccgt cgcaaagagt ttgtctcatg gtgatttcct
    25801 tagacggcaa tagcgattag cagcacaacc agtgcggcga ccacatacag gcaatagaga
    25861 cgaaagtcgc cgctttgcag atgctgtatt tctttggcca gccgttgggt ggcgctcacg
    25921 atggggcgga tcacccgctc atcccagaag ggttctgtgc tctgagccct ggcggtgacg
    25981 tgcgcaagac ctttatttag cctcagcgta gggtcgagct gttgtcgtag acgaaatagc
    26041 gcagaaaaga ccacacgcag cggctgcatc acgccattgc ctgacggggc catcgcattt
    26101 tcccagccgt agccgcatgc ccaggcatct cctgtgcgac gaaacgctgc gcggcgcgaa
    26161 cgacaccaca gccagtaaag gccaggcagc aaaggcatcg ccagtagtaa cagcaacagt
    26221 aatgaggggg tgacctgtgt atgaaacgtg ccgggtacaa gtgctattcc gctggcgaca
    26281 gtggcgggag gggtattggt aaacgcatgg gcaatatgca ttatcttcgg tgccagccaa
    26341 ctggcactaa gcgcaattaa tacgcagagt gccgcgagca gtagcatggc gacgatcatc
    26401 gtatttggca cttcctgtgc ctcttcagcg tgtgtactgc gcggcgcacc acagaaagta
    26461 ataccgtaca tttttacgaa gcacattact gccagcccac cagtgactgc cagcattacc
    26521 atagcaatag gacccgcaag ttgtagcgct acggcttcca cacgacttag tgagaacagc
    26581 gactgccagg tgtaccattc gctgataaaa ccattcagcg gaggaatggc tgatatcgcg
    26641 aggcaaccaa tcaggcatgc tgcggctgtc cacggcatcc gtttcgctag tgcccccatt
    26701 ttttccatgt cgtgggtatg caaacgcgaa ataatcgctc ccgcgccgag aaatagcagc
    26761 cctttgaaca gcgcatggtt gagcagatga aacagtgcgc cgagcagtcc aaccacggtg
    26821 agcagcgggt cgtgcagtga cagaccgacc atcgccacac cgactgccag caaaataatg
    26881 ccgacgtttt cgacggtact ccaggccagc agccgtttga tatcctgttc cgccagcgca
    26941 tatagcacgc ccaggagcgc ggagattgcg ccgatcgcca tcaccagaat gccccaccac
    27001 agaggcaaac ccgtttgcgc cagcagatcc atcgctactt tcaggatgcc gaaaatacct
    27061 attttgacca ttacgccaga catcaacgcc gaagcgtgcg atggtgcggc agggtgagcg
    27121 cgcggcaacc agctgtgcaa cggtatcatc ccggctttcg cgccaaaacc gaaaaaggcc
    27181 agcagaaaca ccgccgacgc cagccccgga gaaagtgaaa gcgtgcgaat ctggcaaaat
    27241 cgaggctgcc gctttcgcgc cccatcagca agaaggcgat cataatcagc accgatccgg
    27301 cgtgggcgat aaaaaagtag agcatgccag cgttgatcga cgttttatcc tgcctggcaa
    27361 tgaccagaaa ccaggaagac agcgacatca tttcaaacag cacgatgaac caaaaagcgt
    27421 tgtccatcac cagcagggca accatcgatg cgatgaaaag attcataaag aagcccatcg
    27481 ccgccgcgcc tttgccctcg tattcgcgca tataagtcaa tgaatagagc gaacaaacca
    27541 ccaccagcaa ggagataacc agcaccataa atgccgagag gctatccatt cgcagggtta
    27601 aatcggcaaa gtcaaaaggg gtggcaaaat gggcgactaa agttacacca gcatgtaatt
    27661 gcgtaattcc gctgatgatg ccaatcacgc cgcccaccag cgatgtgatg ccggaaagct
    27721 taatagccag tctgtccaga ccgagtaaaa acagcgaagc cagactggca aacagataga
    27781 ggatcagcga ccaggttaat aattgcaggg catccattag cgttgctcct gagtgaggga
    27841 aaggggatcc tccccgccat tggcaaacca gcttgcggca aggcgctgtt tttctttcat
    27901 ctgacgttgc aggctatcgt cggtgatcag ccgtaacgcc tgattcgggc aagcgcgaac
    27961 gcaggccgga ccttctggca agaaatcaca caggtcgcat ttcaccgcga cggtctggac
    28021 accaggttcc cagcgcagca acgcatgttg gggcagcacg ttttcttcgc cgtttttgag
    28081 tgagccttca gcctgaaaaa catattgcgc atgggcattc accggacggc ttcctgaagc
    28141 gctgattgcg ccaaatgggc agaccacggc gcaaagcttg cagccaatac agaggctttc
    28201 gttgagttgg atcgcatcat ccctctgaga gatggcattg accgggcaga cctgcaggca
    28261 aggggcttcc tcacagtgat gacacacgac aggggcagtg attgttgacg tcttcgccag
    28321 ggccaggcgc gggtgttgct gtaaaccttg cgttttatgc acgtccgaac aggcagcgag
    28381 acaggtatta catcctgtac accacagtgg ttcggccacc acaaagcggt tcatgtcggc
    28441 tccttgaaaa tgatatgaaa cattgcattt catattgcat aaaggatgcc attctgatta
    28501 actcaatata ttcaataagt tatgtattaa ctggattctg aacggtacaa aaatgatggt
    28561 cattaacgtt cagcaaaaaa tggattcgac acccgtgtcg caggggaaag cgagaatgtg
    28621 atcttcatca cgagaagtga ggtatgctgg ccgcaagcgc agccagcacg gaatggagca
    28681 aagtaatcag gcgtgttctt tcagccagtt cagcacaacg tcgtggtgat tgctggtttt
    28741 gaaatcgtca aagacatgtt cgattttgcc atcagcgtca atcaggaagc tgatgcgatg
    28801 aatgccatcg taggttttgc ccatgaagga cttttcaccc cagacgccga attgttcgca
    28861 cacctggtgg tcctcatcag acaggagcgt aaagttaagc agctcttttt ccgcaaaacg
    28921 ggagagtttt tcgggtttat cggtgctgat acccagcaca tcaacgcccg cttttttcaa
    28981 ctcatccatg ttatcgcgta agccgcaggc ctgtacggta cagccggggg tcatggcttt
    29041 cgggtagaaa taaaccagaa cacgctgtcc ctggaagtcg gtcaaattaa cttgttctcc
    29101 gtcttgatcc ggcaagctaa atttcggtgc gatatcaccg gctttcagtg gattcattac
    29161 ttaactccat cctgttcatc atgttgggaa taattgacga cgttaatact gccttgtgca
    29221 ttgagttctg tacatagggc tttgaacgct tgctcaatat ttgctgcgtc cgcagatgcg
    29281 gggctgtggg cggttatctg aatatgcaac tgcgcagccc gttcattttc agcaggttgc
    29341 gtgcgcgaca ccagctccgc aatgttcata tgatgcgcgt cgaaaagtgc tgtgaagcgt
    29401 tcaattaaat gcggggagtc tgccacatcg acctgaaccc agacagatgc tggcattggc
    29461 ggacgcggac gcgccgtcgt gcgcttcatc acgattaaaa gatccagttc ggcacctttc
    29521 aacggtaacg ttgattcaat cagagtaatg gcattccatg aaccggaaag cagcataata
    29581 aacgtgaact cttctcccag catcgccagg cgactgtctt caatattaca gccgcaacta
    29641 ctgacatgac gggtgatggt gttcacaatt ccagggcgat cggcacccaa cgcagtgatc
    29701 accagataat gttgcgatga cagtgtcaaa ctggttattc ctttaagggg tgagttgttc
    29761 ttaaggaaag cataaaaaaa acatgcatac aacaatcaga acggttctgt ctgcttgctt
    29821 ttaatgccat accaaacgta ccattgagac acttgtttgc acagaggatg gcccatgttc
    29881 acgggaagta ttgtcgcgat tgttactccg atggatgaaa aaggtaatgt ctgtcgggct
    29941 agcttgaaaa aactgattga ttatcatgtc gccagcggta cttcggcgat cgtttctgtt
    30001 ggcaccactg gcgagtccgc taccttaaat catgacgaac atgctgatgt ggtgatgatg
    30061 acgctggagc tggctgatgg gcgcattccg gtaattgccg ggaccggcgc taacgctact
    30121 gcggaagcca ttagcctgac gcagcgcttc aatgacagtg gtatcgtcgg ctgcctgacg
    30181 gtaacccctt actacaatcg tccgtcgcaa gaaggtttgt atcagcattt caaagccatc
    30241 gctgagcata ctgacctgcc gcaaattctg tataatgtgc cgtcccgtac tggctgcgat
    30301 ctgctcccgg aaacggtggg ccgtctggcg aaagtaaaaa atattatcgg aatcaaagag
    30361 gcaacaggga acttaacgcg tgtaaaccag atcaaagagc tggtttcaga tgattttgtt
    30421 ctgctgagcg gcgatgatgc gagcgcgctg gacttcatgc aattgggcgg tcatggggtt
    30481 atttccgtta cggctaacgt cgcagcgcgt gatatggccc agatgtgcaa actggcagca
    30541 gaagggcatt ttgccgaggc acgcgttatt aatcagcgtc tgatgccatt acacaacaaa
    30601 ctatttgtcg aacccaatcc aatcccggtg aaatgggcat gtaaggaact gggtcttgtg
    30661 gcgaccgata cgctgcgcct gccaatgaca ccaatcaccg acagtggtcg tgagacggtc
    30721 agagcggcgc ttaagcatgc cggtttgctg taaagtttag ggagatttga tggcttactc
    30781 tgttcaaaag tcgcgcctgg caaaggttgc gggtgtttcg cttgttttat tactcgctgc
    30841 ctgtagttct gactcacgct ataagcgtca ggtcagtggt gatgaagcct acctggaagc
    30901 ggcaccgctt gcggagcttc atgccccggc tggaatgatt ttgccggtga cctccggtga
    30961 ttatgcaatc ccggtgacca acggtagtgg tgctgtcggt aaggcgctgg acattcgtcc
    31021 accagcccag ccgctggcac tggtttctgg cgcgcgtacc cagttcacgg gcgataccgc
    31081 ttcattgctg gtggaaaatg gtcgtggcaa tactctgtgg ccgcaggtgg ttagcgtgct
    31141 gcaggcgaaa aactacacca tcacccaacg tgatgatgct ggtcagacac tgaccaccga
    31201 ttgggtacaa tggaaccgtc tggacgaaga cgagcagtat cgtggtcgtt atcaaatctc
    31261 tgttaagccg cagggttatc agcaggcggt tacggttaaa ctgctgaacc tggaacaggc
    31321 gggcaaaccg gttgcagacg cggcttccat gcagcgttac agcacggaga tgatgaacgt
    31381 tatttccgcc ggtctggata aatctgccac tgacgccgcg aacgctgcgc aaaatcgtgc
    31441 ctccaccact atggacgtac aaagtgcagc tgatgacacc ggtttaccaa tgctggtcgt
    31501 acgcgggccg ttcaatgtgg tttggcaacg tctgccagcg gcgctggaaa aagtgggcat
    31561 gaaagtgacc gacagcaccc gttcgcaggg caacatggcc gtaacttata agccgctgtc
    31621 tgacagcgac tggcaggaac tgggcgcgag cgatccaggc ctggcatccg gtgactataa
    31681 actgcaggtt ggcgatttag ataaccgcag cagcctacag ttcatcgatc cgaaaggtca
    31741 tactctgact cagagtcaga acgacgcgct ggtagctgtc ttccaggctg cgtttagcaa
    31801 gtaaaaatac agggctggaa tcatccggcc cttttttctg atatgatacg caaacgtgtg
    31861 cgtctgcagg aaaacgcgat tttagcggta attcgcacga aatttgtttg tcggacgtag
    31921 ttcggataag gcgttcacgc cgcatccgac aaaacatccg gcacaccaga cagcaaaaga
    31981 ttttaaaacg ttaattcaca cccaggagtg ataaagatgc aaaagcaagc tgagttgtat
    32041 cgtggtaaag cgaaaaccgt atacagcacg gaaaacccgg acctgttggt gctcgaattc
    32101 cgcaatgata cgtcagcagg ggatggcgcg cgcattgagc agtttgatcg caaaggtatg
    32161 gtgaacaaca agttcaacta cttcattatg agcaaactgg ctgaagcggg tatcccgact
    32221 caaatggagc gtctgctctc cgataccgaa tgtctggtga aaaagctgga tatggtgccg
    32281 gttgagtgtg tcgtgcgtaa ccgtgctgct ggctctctgg tgaaacgtct tggaatcgaa
    32341 gaaggtattg agctgaaccc gccgctgttc gatctgttcc tgaaaaacga cgccatgcac
    32401 gatccgatgg tcaacgaatc ttactgcgaa acctttggct gggtgagcaa agagaacctg
    32461 gcgcgtatga aagagctgac ctacaaagcg aacgacgtgc tgaaaaaact gttcgatgat
    32521 gctggtctga ttctggtcga cttcaagctg gagtttggtc tgtacaaagg tgaagtggta
    32581 ctgggcgatg agttttcccc ggacggcagc cgcctgtggg acaaagaaac gctggagaaa
    32641 atggacaaag accgtttccg ccagagcctc ggtggcctga tcgaggccta tgaagccgtc
    32701 gcccgccgcc tgggtgtaca gctggactga tttttctgtt catcatcttg ccgtgcagct
    32761 ggcacggcaa gacaaccgct ctcggaatat atgcattgaa cgctcattcc tccgccattt
    32821 catcccgctt tcctgtggta atcttcctct gaaccaccta cgatcatttc tataatgaat
    32881 atattgttga ggtatctatg cgttggcaag ggcgacgtga aagtgacaat gttgaagaca
    32941 ggcgcaacag ctctggtggt ccgtctatgg gcggtcccgg ttttcgcctg ccgagcggta
    33001 aaggcgggct gattttactg atagtcgtgc tggttgcagg ctactatggc gttgatttaa
    33061 ccgggttgat gaccgggcag ccggtttctc aacagcaatc aacgcggtca attagcccaa
    33121 atgaagacga agccgcaaaa ttcacctcgg tgattctggc aaccacggaa gacacctggg
    33181 gacaacagtt cgaaaagatg ggtaagacct atcagcaacc gaagctggtc atgtaccgtg
    33241 gaatgacgcg taccggctgc ggggcgggcc agtccataat ggggccgttc tattgcccgg
    33301 cggatggcac ggtttatatc gatctctcct tctatgatga catgaaagac aaacttggcg
    33361 cggatggcga ttttgcccag gggtacgtta tcgcccatga agtcggtcat catgtgcaga
    33421 aactgttagg catcgagccg aaagttcgtc aactgcaaca aaacgcgacg caggcggaag
    33481 taaaccgctt atctgtgcgt atggaactcc aggccgactg ttttgccggt gtctgggggc
    33541 atagtatgca gcagcaaggc gttctggaaa ccggcgatct ggaagaggcg ctgaacgcgg
    33601 cgcaggccat cggcgatgac cgtttacaac agcaaagtca ggggcgagta gtaccagaca
    33661 gtttcactca tggcacttct cagcaacgct acagctggtt taaacgtggt ttcgacagcg
    33721 gcgatccggc acaatgcaat acttttggta aaagcattta acttccgggg cagggatggc
    33781 tgaactgact gcgcttcaca cattaacagc gcaaatgaaa cgtgaaggga tccgccgctt
    33841 gctggtgttg agcggggaag agggttggtg ttttgagcat actcttaagt tgcgtgatgc
    33901 cttacctggc gactggctgt ggatttcgcc gcggccagat gctgaaaacc actgttctcc
    33961 ctcggcacta caaactttac ttgggcgcga gttccggcat gcggtattcg acgcccgcca
    34021 cggctttgat gccgctgcct ttgccgcact tagcggaacg ttgaaagcgg gaagctggct
    34081 ggttttgtta ctccctgtat gggaagagtg ggaaaaccaa cctgatgccg actcgctgcg
    34141 ctggagtgat tgccctgacc ctattgcgac gccgcatttt gtccagcatc tcaaacgcgt
    34201 acttacggcg gataacgagg ctatcctctg gcggcaaaac cagccattct cgttggcgca
    34261 ttttactccc cgtactgact ggtaccccgc gactggcgca ccacaaccag aacaacagca
    34321 actcttaaag cagctaatga ccatgccgcc gggcgtggca gcggtaacgg ctgcgcgtgg
    34381 gcgcggtaag tcggcgttgg cagggcaact catttctcgt attgtgggca gagcgattgt
    34441 caccgcgccc gcaaaagcgt caacggatgt actggcacaa tttgcgggcg agaagtttcg
    34501 ctttattgcg ccggatgcct tgttagccag cgatgagcaa gccgactggc tggtggtcga
    34561 tgaagccgca gccatacctg cgccattgtt gcatcaactg gtatcgcgtt ttcctcgaac
    34621 gttgttaacc actacggtgc agggctacga aggcaccgga cgtggttttt tgctgaaatt
    34681 ttgcgctcgc tttccgcatt tacaccgttt tgaactgcaa cagccgatcc gctgggcgca
    34741 gggatgcccg ctggaaaaaa tggtcagcga ggcactggtt tttgacgatg aaaacttcac
    34801 ccatacacca caaggcaata ttgtcatttc cgcatttgaa cagacgttat ggcaaagcga
    34861 tccagaaacg ccgttaaagg tttatcagct cttgtctggt gcgcactatc ggacttcgcc
    34921 gctggattta cgccggatga tggatgcacc agggcaacat tttttacagg cggctggcga
    34981 aaacgagatt gccggggcgc tgtggctggt ggatgagggt ggattatctc aacaactcag
    35041 tcaggcggta tgggcaggtt ttcgtcgccc gcggggtaat ctggtggccc agtcgctggc
    35101 ggcgcacggc aacaatccac tggcggcgac attgcgtgga cggcgggtca gccggatagc
    35161 agttcatccg gctcgtcagc gggaaggcac agggcggcaa cttattgctg gtgctttgca
    35221 atatacgcaa gacctcgact atctttcggt gagttttggt tacaccgggg agttatggcg
    35281 tttctggcaa cgctgcggtt ttgtgctggt gcggatgggt aatcatcggg aagccagcag
    35341 cggttgctat acggcgatgg cgctgttacc gatgagtgat gcgggtaaac agctggctga
    35401 acgtgagcat taccgtttac gtcgcgatgc gcaagctctc gcgcagtgga atggcgaaac
    35461 gcttcctgtt gatccactaa acgatgccgt cctttctgac gacgactggc ttgaactggc
    35521 cggttttgct ttcgctcatc gtccgctatt aacgtcgtta ggttgcttat tgcgtctgtt
    35581 acaaaccagt gaactggcat taccggcgct gcgtgggcgt ttacagaaaa acgccagtga
    35641 tgcgcagtta tgtaccacac ttaaactttc aggccgcaag atgttactgg tccgtcagcg
    35701 ggaagaggcc gcgcaggcgc tgttcgcact taatgatgtt cgcactgagc gtctgcgcga
    35761 tcgcataacg caatggcaat tatttcactg actccttcaa ttttatctca tggtcattgt
    35821 gagtcagcgg cgtaaaatta atgacatcag ttaaggagtt cgccatgaaa catgaccatt
    35881 ttgttgttca aagcccggat aaacctgcgc aacagttgtt actgcttttc cacggtgtcg
    35941 gggataaccc ggtggcaatg ggggaaatag gcaactggtt tgcaccgctg tttcctgatg
    36001 cgctggtggt gagtgtcggt ggcgcggagc cgagcggtaa tccggcgggg cgtcagtggt
    36061 tttcggtgca gggtattacg gaagataatc gccaggcgcg tgtggatgcg atcatgccga
    36121 cgtttattga aacggtgcgc tactggcaga aacagagcgg agtaggggct aacgccacgg
    36181 cgctcatcgg tttctctcaa ggcgcgatta tggtgctgga gagcattaaa gccgaaccgg
    36241 gccttgcttc acgcgtcatt gcttttaacg gacgctatgc gagcctgccg gaaactgcgt
    36301 ctacagccac gacaattcac ctgattcatg gcggtgaaga tccggttatc gatctggcgc
    36361 atgcggttgc ggcgcaggaa gcgttaatca gtgccggtgg tgacgtgacg ctggatatcg
    36421 tggaggattt aggccatgcg atcgacaatc gcagtatgca atttgccctg gatcacttgc
    36481 gttataccat tccgaaacat tatttcgacg aagcgctaag tggcggtaag cctggcgatg
    36541 atgatgtgat tgaaatgatg taaaagacag attacctggc ctgataagac gcgtgagcgt
    36601 cgcatcaggc atcgttcacc attgccggat gcggcgttaa cgccttatcc ggcctacggt
    36661 tgagcactca gcttacttct tcggttgatc ctttttcggc cagtcgtcgt catcgtccca
    36721 cttatcgttg aaatcacgat gcgggggaag ctccggcttg ttggcgagaa atttcttatg
    36781 gtcgacgcgc ttgagatctt taatcacgtt cagcaggacg cctaccaaaa agacaatcac
    36841 cagaatccac caatatttag ccagccagtc catgcttatt tcctcttgca gaaccactca
    36901 tcaggcgacg agctgttcca tgatacgttg atacatacgg gcaagtagct gcaggtcggc
    36961 agcgttcaca cattcattaa ttttatgaat agtggcattg accggcccga gttccaccac
    37021 ctgcgccccc atgcgggcaa taaagcgccc gtcggacgtt ccgcctgtgg tcagtagctg
    37081 cggtttaatt tcattatagt gctcaaccgc gttaacgacc gcatccacca gtttaccgcg
    37141 cgcggtcaaa aatggctgcc cggaaagcca ccaatccacc gtatagcgca gttgatgttt
    37201 ttcaagcagg gcaagcacct gcgctttgat catctcatca gtcagttcgg tgctgaagcg
    37261 gaagttaaac tgcacaaaca gttcacccgg aataacgttg ttactgcccg ttcccgcctg
    37321 aatattggca atctgcatac tggtcgccgg gaagaattca ttgccctgat cccactcaat
    37381 agccactaat tcattaagga aaggtgctgc gcgatgtacc ggattgtcag ccagatgtgg
    37441 gtaggcaaca tgcccctgaa cgccatgaat ggtaaggttg caggttaatg atccgcgacg
    37501 accatttttc accacatcac ctaccacttc gatactcgac ggttcgccaa ccaggcagta
    37561 atcgagacgc tcattacgtg ccattaacgc ttcgacgact tttaccgtac cgttgtgggc
    37621 actggcttct tcatcagagg tgatcagaaa tgccagtcgc cccgtatggt tgggatgttg
    37681 tgcgacaaaa cgttctgccg ccaccaccat cgccgccagc gagcctttca tatctgccgc
    37741 accgcgcccg aataacatgc cgtcacgaat ggtgggttca aacgggggat tgatccaacg
    37801 atcggcgtcg ccaggcggca ccacgtcggt atgcccggca aaggctaacg tttcaccctg
    37861 cccacgccat gcccaaaaat tctgcgtatc ggcaaagtcc atgcgttcaa cggtaaaacc
    37921 gatcgcctgc aaacgttcaa tcaacaaagc ctggcatcct gcatcatcag gactcaggga
    37981 agggcggcga ataagctgtt gtgtcagctc aataaccggg cacgacatag actacacctc
    38041 atggaaaaat tgctgataac tggaatcact gaaacccagc agcataggct taccgggcac
    38101 gcagagcaat ggacgtttga taattgcagg catttcagtc attaatgccg ccgcagaggc
    38161 cgcatcggtg attttattgc gggtggtttc gtccagttta cgccaggttg taccacgggt
    38221 gttgagtaac gcttcccagc ctaattcgtt gataaaatcg ttcaataatt cgctgtccag
    38281 cccatcgacg cggtaatcat gaaaacgata gtcgatgtta ttggcttcca gccaacggcg
    38341 agccttttta atggtgtcac aatttttgat accgtaaagt gtaaccataa tgaatccttt
    38401 ttcgatttat gagaataaat actcatttaa gggtgaaaac attttgcctg caaa
//
LOCUS       DAPHKZ010000035        38012 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.035, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000035 DAPHKZ010000000
VERSION     DAPHKZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38012
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.035"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(189..476)
                     /locus_tag="RH288_001858"
     CDS             complement(189..476)
                     /locus_tag="RH288_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HDV4030913.1"
                     /translation="MNEVVNSGVMNIASLVVSVVVLLIGLILWFFINRASSRTNEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKADKKTVESQKSVEDEDIIRLVAER"
     gene            complement(551..694)
                     /gene="mgrB"
                     /locus_tag="RH288_001859"
     CDS             complement(551..694)
                     /gene="mgrB"
                     /locus_tag="RH288_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HDV4030914.1"
                     /translation="MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQF
                     IPW"
     gene            853..1092
                     /locus_tag="RH288_001860"
     CDS             853..1092
                     /locus_tag="RH288_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030915.1"
                     /translation="MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLT
                     ARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG"
     gene            complement(1235..2026)
                     /gene="kdgR"
                     /locus_tag="RH288_001861"
     CDS             complement(1235..2026)
                     /gene="kdgR"
                     /locus_tag="RH288_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HDV4030916.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMREISR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
                     KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQMGYHDYPF"
     gene            2203..3576
                     /locus_tag="RH288_001862"
     CDS             2203..3576
                     /locus_tag="RH288_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4030917.1"
                     /translation="MPKVQADGLPLPQRYGAVLTIVIGISMAVLDGAIANVALPTIAT
                     DLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSD
                     SLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
                     AAILSIASWKWLFLINVPLGIIALLLAMRFLSPNGSRASKPRFDLPSAVMNALTFGLL
                     ITALSGFAQGQSLTLIAAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICT
                     SVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAG
                     LLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRE
                     RSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRI
                     TQPRSRA"
     gene            complement(3622..4503)
                     /gene="htpX"
                     /locus_tag="RH288_001863"
     CDS             complement(3622..4503)
                     /gene="htpX"
                     /locus_tag="RH288_001863"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HDV4030918.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGF
                     GGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFS
                     RHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTH
                     PPLDKRIEALRTGEYLK"
     gene            complement(4695..6743)
                     /gene="prc"
                     /locus_tag="RH288_001864"
     CDS             complement(4695..6743)
                     /gene="prc"
                     /locus_tag="RH288_001864"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HDV4030919.1"
                     /translation="MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGD
                     ELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
                     ELNALWDSKVKFDELSLKLAGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAI
                     SVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLT
                     RERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDL
                     RSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGNLTA
                     FEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRL
                     ARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
                     "
     gene            complement(6763..7461)
                     /gene="proQ"
                     /locus_tag="RH288_001865"
     CDS             complement(6763..7461)
                     /gene="proQ"
                     /locus_tag="RH288_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707288.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HDV4030920.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVD
                     RVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQK
                     PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLN
                     SGMSLIVRAEHLVF"
     gene            complement(7558..8055)
                     /gene="msrC"
                     /locus_tag="RH288_001866"
     CDS             complement(7558..8055)
                     /gene="msrC"
                     /locus_tag="RH288_001866"
                     /EC_number="1.8.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine (R)-S-oxide reductase"
                     /protein_id="HDV4030921.1"
                     /translation="MNKTEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDVNW
                     AGFYLLEDDTLVLGPFQGKIACVRIPVGRGVCGTAVARNQVQRIEDVHAFDGHIACDA
                     ASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVAQLEKVLATTDYKKFF
                     ASVAG"
     gene            8185..9468
                     /gene="yebS"
                     /locus_tag="RH288_001867"
     CDS             8185..9468
                     /gene="yebS"
                     /locus_tag="RH288_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HDV4030922.1"
                     /translation="MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEIN
                     SHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANV
                     MQGIWQMTKQGDTITGAMVFFCVIGAPLILVSSIAYLWFGNRLGMNLRPVLLMLERLK
                     EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFY
                     PQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVL
                     LLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD"
     gene            9437..12070
                     /gene="yebT"
                     /locus_tag="RH288_001868"
     CDS             9437..12070
                     /gene="yebT"
                     /locus_tag="RH288_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding membrane homeostasis protein YebT"
                     /protein_id="HDV4030923.1"
                     /translation="MSQETPASTTEAQIKNKRRISPFWLLPFIALMIAGWLIWDSYQD
                     RGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQDISLSDDLRKIEVKVSIKSDMKDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDNGD
                     LMIHLQAPDLGSLNSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKG
                     SRFWNVSGVDANVSISGAKVKLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAH
                     SQRGVITKLELPSGAGLTADSTPLMYQGLEVGQLTKLDLNPGGKVTGEMTVDPSVVTL
                     LRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLHEPDV
                     LTLTLTAPESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWINGGIRILPGDKGEMKASYPLYANLEKALENS
                     LSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLHIKPEYRNL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASQRKGDKRILY
                     ASETAARAVGGQITLHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLY
                     PEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPYINVEPGRGNPRRDFELQEATIT
                     DSRYLDGLSIIVEAPEAGSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
                     QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGK
                     HFLLQESEPKEWREWGTALPK"
     gene            12150..13589
                     /gene="rsmF"
                     /locus_tag="RH288_001869"
     CDS             12150..13589
                     /gene="rsmF"
                     /locus_tag="RH288_001869"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HDV4030924.1"
                     /translation="MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVN
                     TLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGVILANEFSASRVKVLHA
                     NISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     QEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEVVCLWLKETYPDAVEFLPLGD
                     LFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPTPKYKVGNFPFSPVKD
                     REAGQIRQAAASVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHN
                     KGYRWQHEAVIALATPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPI
                     GLAKRIGSRLKNSYPRELVRDGKLFTSNA"
     gene            13707..13943
                     /locus_tag="RH288_001870"
     CDS             13707..13943
                     /locus_tag="RH288_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HDV4030925.1"
                     /translation="MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAW
                     DAETSIPALLNGEHSILYRTRYDQQSDAWIMRLA"
     gene            14048..14239
                     /locus_tag="RH288_001871"
     CDS             14048..14239
                     /locus_tag="RH288_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HDV4030926.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDVYNTEQQCLHSMSDQRIRQGGCF
                     PIEDFIDGFWRPAQEYGDF"
     gene            complement(14240..14896)
                     /gene="pphA"
                     /locus_tag="RH288_001872"
     CDS             complement(14240..14896)
                     /gene="pphA"
                     /locus_tag="RH288_001872"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HDV4030927.1"
                     /translation="MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCRFDPW
                     RDLLISVGDVIDRGPQSLRCLQLLEQHWVRAVRGNHEQMAMDALASQQMSLWLMNGGD
                     WFIALADNQQKQAKTALEKCQHLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
                     VLWSRSRLGERPKGQGITGADHFWFGHTPLRHRVDIGNLHYIDTGAAFGGELTLVQLQ
                     "
     gene            complement(15292..15633)
                     /locus_tag="RH288_001873"
     CDS             complement(15292..15633)
                     /locus_tag="RH288_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HDV4030928.1"
                     /translation="MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEV
                     MLTCRPGNALYVINPSTLVQYPLNDIAQKEVASGKTKAQPISVIQIDDPNNPGEKMSL
                     APFIERAEKLC"
     gene            complement(15646..16518)
                     /gene="copD"
                     /locus_tag="RH288_001874"
     CDS             complement(15646..16518)
                     /gene="copD"
                     /locus_tag="RH288_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HDV4030929.1"
                     /translation="MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLAKRFL
                     RLQQHAAVWSLISATAMLAVQGGLMGTGWTDVFSPNIWQAVLQTQFGGVWLWQIVLAL
                     VTLIVALMQPRNMPRLLFMLTTAQFFLLAGVGHATLNEGVTEKIHQTNHAIHLICAAA
                     WFGGLLPVLWCIQLIKGRWRHQTIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPT
                     LTTYWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAV
                     VLVIISLLATLEPF"
     gene            complement(16522..16896)
                     /gene="yobA"
                     /locus_tag="RH288_001875"
     CDS             complement(16522..16896)
                     /gene="yobA"
                     /locus_tag="RH288_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HDV4030930.1"
                     /translation="MASTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAA
                     PQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYT
                     VDWHVVSVDGHKTKGHYTFSVK"
     gene            17035..17265
                     /gene="holE"
                     /locus_tag="RH288_001876"
     CDS             17035..17265
                     /gene="holE"
                     /locus_tag="RH288_001876"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HDV4030931.1"
                     /translation="MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQ
                     PEHLRSWFRERLIAHRLASVNLSRLPYEPKLK"
     gene            17367..18023
                     /locus_tag="RH288_001877"
     CDS             17367..18023
                     /locus_tag="RH288_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDV4030932.1"
                     /translation="MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPS
                     LSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTIIAGLPVEYNDRFIRGIAVFAPW
                     RKTPGIYHQSHGACLGRRSRTITVVDEQPQGMDMDPTCSLFTTGQCLGEPDLLASARR
                     LQFFSHQYSIAVLMANARGNSALWDEYGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
                     "
     gene            18047..18709
                     /gene="exoX"
                     /locus_tag="RH288_001878"
     CDS             18047..18709
                     /gene="exoX"
                     /locus_tag="RH288_001878"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HDV4030933.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPIS
                     PQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKL
                     ARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
                     MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLGSMSPELRLTLKHYLE
                     NT"
     gene            complement(18706..20766)
                     /gene="ptrB"
                     /locus_tag="RH288_001879"
     CDS             complement(18706..20766)
                     /gene="ptrB"
                     /locus_tag="RH288_001879"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HDV4030934.1"
                     /translation="MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQEN
                     SYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQS
                     AFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
                     ETGNWYPELLDNVEPSFVWANDSWTFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYE
                     EKDDTYYVSLHKTTSKHYVVIHLASATTSEVRLLDAEMADAEPFVFLPRRKDHEYSLD
                     HYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIPPRENIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFDAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVY
                     GYGSYGASIDADFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDY
                     LDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTML
                     DESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDNHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPA
                     TPAD"
     gene            complement(20975..21634)
                     /locus_tag="RH288_001880"
     CDS             complement(20975..21634)
                     /locus_tag="RH288_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HDV4030935.1"
                     /translation="MANWLNQLQSLLGQSSSSTSSSADQGLGKLLVPGALGGLAGLLV
                     ANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERT
                     ERLILALVFAAKSDGHIDAKERAAIDQQLREAGVEEQGRVLIEQAIEQPLDPQRLATG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVRDGIERDLEQQKRTLA
                     E"
     gene            complement(21961..22317)
                     /locus_tag="RH288_001881"
     CDS             complement(21961..22317)
                     /locus_tag="RH288_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YebF"
                     /protein_id="HDV4030936.1"
                     /translation="MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIA
                     ASVKRDYQQNRVARWADDQKIVGQADPVAWVSLQDIQGKDDKWSVPLTVRGKSADIHY
                     QVSVDCKAGMAEYQRR"
     gene            complement(22384..22674)
                     /gene="yebG"
                     /locus_tag="RH288_001882"
     CDS             complement(22384..22674)
                     /gene="yebG"
                     /locus_tag="RH288_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HDV4030937.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTN
                     SPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA"
     gene            22808..23986
                     /gene="purT"
                     /locus_tag="RH288_001883"
     CDS             22808..23986
                     /gene="purT"
                     /locus_tag="RH288_001883"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HDV4030938.1"
                     /translation="MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRY
                     ADAPAMHVAHRSHIINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVV
                     PCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSS
                     SGKGQTFIRSAEQLAQAWKYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN
                     VTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
                     "
     gene            complement(24042..24683)
                     /gene="kdgA"
                     /locus_tag="RH288_001884"
                     /gene_synonym="eda"
     CDS             complement(24042..24683)
                     /gene="kdgA"
                     /locus_tag="RH288_001884"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDV4030939.1"
                     /translation="MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVL
                     EVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
                     TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL"
     gene            complement(24720..26531)
                     /gene="edd"
                     /locus_tag="RH288_001885"
     CDS             complement(24720..26531)
                     /gene="edd"
                     /locus_tag="RH288_001885"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HDV4030940.1"
                     /translation="MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWM
                     PIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMA
                     RLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGEL
                     DWREGAEKSLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVV
                     FESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE
                     PHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF"
     gene            complement(26766..28241)
                     /gene="zwf"
                     /locus_tag="RH288_001886"
     CDS             complement(26766..28241)
                     /gene="zwf"
                     /locus_tag="RH288_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDV4030941.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTR
                     IIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFNLL
                     GAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEIN
                     DQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPG
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            28579..29448
                     /gene="hexR"
                     /locus_tag="RH288_001887"
                     /gene_synonym="yebK"
     CDS             28579..29448
                     /gene="hexR"
                     /locus_tag="RH288_001887"
                     /gene_synonym="yebK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HDV4030942.1"
                     /translation="MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAAMALEA
                     NVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESA
                     MATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
                     DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKES
                     RFDKQLLNLSDDR"
     gene            29576..31018
                     /gene="pyk"
                     /locus_tag="RH288_001888"
     CDS             29576..31018
                     /gene="pyk"
                     /locus_tag="RH288_001888"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDV4030943.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCSQDAIDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGY
                     LMSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(31149..32120)
                     /gene="lpxM"
                     /locus_tag="RH288_001889"
                     /gene_synonym="msbB"
     CDS             complement(31149..32120)
                     /gene="lpxM"
                     /locus_tag="RH288_001889"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416369.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HDV4030944.1"
                     /translation="METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFR
                     DPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMAMMAE
                     LAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHT
                     IARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(32240..33562)
                     /gene="mepM"
                     /locus_tag="RH288_001890"
     CDS             complement(32240..33562)
                     /gene="mepM"
                     /locus_tag="RH288_001890"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HDV4030945.1"
                     /translation="MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRD
                     ATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVST
                     GDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
                     TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQ
                     WQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRN
                     GTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGE
                     VVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGP
                     HLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD"
     gene            complement(33578..34510)
                     /gene="znuA"
                     /locus_tag="RH288_001891"
     CDS             complement(33578..34510)
                     /gene="znuA"
                     /locus_tag="RH288_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HDV4030946.1"
                     /translation="MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIAD
                     GVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQV
                     TIAQLEDVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
                     KLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFG
                     LTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMG
                     TLDPLGTNIKLGKTSYSEFLSQLANQYASCLKGD"
     gene            34589..35344
                     /gene="znuC"
                     /locus_tag="RH288_001892"
     CDS             34589..35344
                     /gene="znuC"
                     /locus_tag="RH288_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HDV4030947.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKS
                     TLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDIL
                     PALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS"
     gene            35341..36126
                     /gene="znuB"
                     /locus_tag="RH288_001893"
     CDS             35341..36126
                     /gene="znuB"
                     /locus_tag="RH288_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HDV4030948.1"
                     /translation="MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVS
                     LMSNIRVDLMAYLFGDLLAVTPEDLISIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     LVGMVAVTGGLTFSAFYDTPAGPSVVLCAALLFILSMMKKQAS"
     gene            complement(36273..37283)
                     /gene="ruvB"
                     /locus_tag="RH288_001894"
     CDS             complement(36273..37283)
                     /gene="ruvB"
                     /locus_tag="RH288_001894"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDV4030949.1"
                     /translation="MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIF
                     IKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPE
                     MP"
     gene            complement(37292..37903)
                     /gene="ruvA"
                     /locus_tag="RH288_001895"
     CDS             complement(37292..37903)
                     /gene="ruvA"
                     /locus_tag="RH288_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDV4030950.1"
                     /translation="MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL"
BASE COUNT         9101 a         9801 c         9382 g         9728 t
ORIGIN      
        1 taaacatcct aataaattaa tgaggaaaat atctttttct gatatcccgt tacgcaaata
       61 aataatatga taattatttg aagtcagacc agagttttaa tttgaagcag ttgcaccatg
      121 gcagtgcgta taatcaggat gaattgagta acccttcaac gacggggtta ctcaagattg
      181 aggaaggatt atcgttcggc gaccagacga ataatatctt cgtcttcaac cgatttttga
      241 ctctcaacgg tctttttatc tgctttctca ggttcgtttg cttcgcacaa acgacgtaac
      301 agtgcatttt gacgtttttg ctgatccagc aacgcctcaa gcagttcaat ctgttcgtta
      361 gtccgagaac tggcacgatt gataaaaaac cacaagatga gcccgataag aagaaccacc
      421 accgatacaa ccaaagacgc aatgttcatc acgcctgaat ttacaacttc gttcatttca
      481 ccacctctga gtagaggcgc tattctacca ctgctggaga ggaagaaaat ctagtgctga
      541 aaaaatgata tcaccacggg ataaactggt taatggcaca aattccgctg aaaaattgta
      601 catcctgatc gcacatcatg ttgaatacct gcgcccaaag cagcaagcaa gccaacacca
      661 cgacaaccag aacgacccat cgaaactttt tcactccaat ctccgcttca cctaccttat
      721 gtcattaaac tagcatgcgt tagttaaaca gcgcctaact atgtcgatat tcgtgctttt
      781 tcggaatgag tagcttgctt cagcgcatat tgccgctacg attaagcgaa cataaaaaga
      841 gaagaggttg taatgcgatt catcattcgc acagttatgc tgatagcact ggtatggata
      901 ggattattac tcagcggata tggcgttttg attggaagca aagagaatgc cgcaggatta
      961 ggtttgcaat gtacctatct gactgccaga ggcaccagca cggtacaata cttgcacact
     1021 aaaagtggtt tcttggggat aacagattgc ccactgttac gtaaaagcaa tatcgtggtc
     1081 gataatggtt aagggtaata aataaccaga ttctcactca tgagtaaaat attcttatag
     1141 caagcgcgtt taatataacg caccttcaac tttatttttc tcatgctaaa taaagaacct
     1201 gtctgtttga tattccgaca ggttcttact ctcatcagaa cggatagtcg tgataaccca
     1261 tttgggcaga aattttgcgc gctgcggtat gcaacattgc gacatattcc tgtaaacgct
     1321 cttcagagaa acgcaacgtc gggaaggaga tgctcaaacc ggcaatgacc acgccaaagc
     1381 gatcaaatac cggtaccgca atgcatcgca gcccttcttc ctgctcttcg ttatcttcgc
     1441 catacccctg ctcgcgcacc tggtccagaa cgggtaataa cgcttctgta ctggtgatgg
     1501 tccgctcggt actgcgttta tactccacgc cctcaagaat ttgcttcact tcatcgcgat
     1561 cgcgccatgc cagcagtacc ttaccaatcg cggtgctgta cagcggatta cgacgcccaa
     1621 tccgtgaata catgcgcaaa ttgtacatag agtcaatttt gtgaatgtaa acaatactgt
     1681 cttcgtccag tgcgccgagg tggatagttt ctttggtcag gcgggagatc tcacgcatct
     1741 ggatatctgc gctacgaatt aaatcgacgt tttgtaacgc gcgagcgccc agttcaaaca
     1801 atttcagggt cagggaatat ttctccgact ccccttcctg cgccacataa cctaaggttt
     1861 tcatggtctg taaaaagcga taaacggtgc tttttgacat catgacgcgc tgcgacagct
     1921 cggttatccc tatttcgcgc tcttcaccca gcgcctgcaa aatgccaaaa acttttagca
     1981 cggaagatac agaatcaggc tgtttatcca gatctgcgtt agccatttat cacctcattg
     2041 cgagtgtttt ataaaaatca gaactgtttt ttattataat ttcgcaccag ggtggtcgca
     2101 atccatcttt tgccggttag ttacaattct gcgacatcca ccgtgaatat cagtgctaga
     2161 atcatacccc tgttgattat tcaccaaaga tataaaattc ctatgccaaa agttcaggcc
     2221 gacggcctgc cattgcccca gcgatacggt gcggtattaa ccattgtgat tggtatttcg
     2281 atggctgtcc ttgacggcgc aatcgccaac gtcgccctgc caacaatcgc cacggacctt
     2341 catgccacgc cagccagttc catctgggta gtgaacgcct atcaaatcgc cattgtcatc
     2401 tccctgctct cgttttcgtt tctgggcgat atgtttggct atcgacgtat ttataaatgc
     2461 ggtctggtcg tttttctgtt gtcttcactg ttctgcgccc tttctgattc gctgcaaatg
     2521 ctcacccttg cgcgtgtcat acaaggtttc ggaggtgcag cgttgatgag cgttaatacc
     2581 gcacttatcc gcctgatcta tccacaacgt tttctgggga gagggatggg cataaactcg
     2641 tttattgttg ccgtctcttc tgctgccggg ccgacaattg ctgcagcaat cctctccatc
     2701 gcatcctgga aatggttatt tttaatcaac gtaccgttag gtattatcgc cctgcttctg
     2761 gcgatgcgtt ttctgtcacc caatggttct cgcgccagta aaccccgttt cgacctgccc
     2821 agcgccgtga tgaacgcgtt aaccttcggc ctgcttatca ctgcgttgag tggtttcgct
     2881 caggggcaat cgctgacgtt aattgctgcg gaactggtgg taatggttgt tgttggtatt
     2941 ttctttattc gccgccagct ttctcttcct gtaccgctgc taccggtgga tttactgcgt
     3001 atcccgctgt tttcactttc tatttgcaca tctgtttgct ctttctgcgc acaaatgctg
     3061 gcaatggttt ccctgccctt ttacctgcaa accgtgctcg ggcgtagtga agtcgaaaca
     3121 ggtttacttc tgacaccgtg gccgttagca acgatggtga tggctccgtt ggcaggctat
     3181 ttgattgaac gcgtacatgc aggattgctg ggtgctctag ggttgttcat catggctgcg
     3241 gggctttttt ccctggttct gctgcccgcg tcacctgcgg atatcaatat tatctggccg
     3301 atgatcttat gtggcgctgg atttggcttg ttccagtcac ccaataacca caccattatt
     3361 acctccgctc ctcgcgaacg tagcggtgga gccagtggca tgttaggaac ggctcgtcta
     3421 ctgggtcaga gtagcggcgc ggcactggtg gcgctgatgc taaatcagtt cggtgataat
     3481 ggtacgcacg tttcgctgat ggctgcggct attctggcag tgattgctgc ctgtgtgagt
     3541 ggtttacgta tcactcagcc acgatccagg gcataaaaaa agcgcgtcga tcaggacgcg
     3601 ctttttagta tttacttcat attacttcag gtattcaccc gtacgcagag cttcaattcg
     3661 tttatccagc ggcgggtgag tcatgaacaa ctcactgagc gatttcgact taccgttaat
     3721 gcagaaagcc atcatgctgg ttgcttcttg cggttcatag ctggttttca ggcgctgcag
     3781 cgcggcaatc attttctcgc gaccaaccag ttttgccgaa ccggcatcag catggaattc
     3841 acgatgacgc gagaaccaca tggtgataat gctcgccaga ataccaaaca ccagttccag
     3901 aaccgttgca accgcaaagt agatcagcgg gttgccgttg ctctcttcac cttcatcacg
     3961 atttccgccc ataaaacccg cggcaagctg cgccagaata cgggaaataa agataacgaa
     4021 ggtgttcacc acgccctgaa tcagcgtcat ggtaaccata tcaccattgg cgatgtggct
     4081 gatttcgtga gcaattaccg cctcggcttc atccgggctc atgttctgca gcaaaccggt
     4141 gctgacagca accagagagg catcacggcg cgcaccggtt gcaaaagcgt tgatgtccgg
     4201 cgcatggtag atagccactt gcggcatagc gatccccgcc tgacgagcct gggttgctac
     4261 agtattgacc agccaacgtt ccctttcgtt acgcggttgc tcgatcactt ccccgccaac
     4321 agatcgtaat gccatccatt tggacatcag aagcgaaacg aaggaaccac caaaaccgaa
     4381 cagcaaggcc atgatcatca gcccctgaac gctgctcgac tgtatccctg tcaggctcag
     4441 taccagcccg aaaacgacca ttacggccag gttcgttagc aggaagagcg cgattcgcat
     4501 cataattttc tttttacctc agtttaacaa aacgcaatat gcgataccca catcgtatgg
     4561 gttacgcgac tattttcaag tctggatagt gcgtaagtca ccagaaagac acaactttac
     4621 attttgtagc atctgattta cggcatcttg ccgctgttaa aaaatcaggc acaatttctt
     4681 gtgcctgatt gatattactt gacgggagcg ggttgttccg cgggtctggc tttttcaagc
     4741 ttcgccagat cgagtgcgat attcaccgtc tcatccagat aaggatccgg ctcctggtaa
     4801 tctttcggta gatcatccag cttcttcaac tccggtttac cttcgcgttt aaagcgttcg
     4861 ttcaaacgcg ccagacgcgt cgcatcatct tcattattct ctttctcacg cacagcgtag
     4921 ttcagagaaa cgatattgcg cttgtccttc atagcgttga agcgcgcgat atccttcatg
     4981 atgttctgga actcaggatc tttcgcgata cgcgcattat gttccttcag cagctccggt
     5041 tcaaaggcag ttaaatttcc tgatttcaca taagtcgcgg catcgatgct atcccacggc
     5101 agcgcgttat cttcgaattt ctcacccgtt tccgtttctt cattacccgt cggcatgatg
     5161 atgtctggcg ttacgccttt acgttgcgta ctgccgccgt taacgcgata gaatttctgg
     5221 atcgtgtact gcacagaacc cagcgctggc cattcaggac gtaacatctg atcgtaaata
     5281 cggttcaatg aacggtattg ctgaacggtg cctttaccaa acgtcggttc acccacaacc
     5341 agcgcacgac cgtaatcctg cattgccgcg gcaaagattt ctgaagccga agcactgaaa
     5401 cggtcaacca gtaccaccag cgggccttta tagaacacct gcccgtcggt atcgctgtct
     5461 tcacgaacct tgccgttgtt atcgcggacc tgaacaatgg gacccgcagg aataaacaga
     5521 cctgagagcg ataccgcttc ggtcaacgcc ccaccgccat tgctacgcag gtcgatgatc
     5581 acactgctga cattctgttt ttccagtttc tgcagttgaa ctttgacatc gtctgtcaaa
     5641 cccacataga agcccggaat atccagcacg ccgactttct ctttaccgac ggtcttcacc
     5701 gacattttaa ccgcgcggtc ttcgagacga atacgttcac gggtcaatgt tacagtgcgg
     5761 gtcttggtcc ctttaccagc aggtaaaatt tccagacgaa ctttactgcc cttcggccct
     5821 ttaattaagg caaccacatc atcaagacgc cagccaatca cgtcaaccat cggcttgcct
     5881 gtttgaccaa caccgacaat tttgtcacca acgctgatag ctttactctt cgctgccgga
     5941 ccacctgcca ccatcgaatt gataacggtg tagtcatcat ccatttgcag cactgcgcca
     6001 ataccttcca gcgacaaact catttcagtg ttgaactgtt cggtattacg cggggaaaga
     6061 tagttggtat gcgggtcgat ttcacgcgca aacgccgtca ttgccagcga gaaaacatct
     6121 tcgctgttgg tttgcgccag acgacgaatg gcaaatttgt agcggcgtgt cagggtttca
     6181 cgaatttctt tatccgtttt tcctgccagc ttcaggctta actcgtcgaa tttgacttta
     6241 ctgtcccaca gcgcgttcaa ctcagcctcg tttttcggcc agggcgcttt gctgcggtca
     6301 aggttataag tgtcgttgcc ggtgaaatcc atcggctttt ccagtaccga caaagcgtac
     6361 tggtaacgct caaaacggcg cttttgcgcc agattgtaga gatcgtagaa aacgtcgagt
     6421 ttgcctgaac gcagttcatc gcctaactcg gttttctttt tcgcgaactg ttcaacatcg
     6481 cttgccagca gcacgttgtg gctgtaatcg agcagattca ggtagcggtc aaagattttg
     6541 gccgaaaatg cctgatcgag gtcgaactgg cgataatgag aacgggtgaa gcgcgacgtt
     6601 acgcgctcac ttaccgtcgc atgctgcgtc tcttccttta ataccggaat ttgatcagca
     6661 cgcgtgatat cttctacagc gaaggtctgg cctgctattg caagcaggcc agctaacgcg
     6721 gtaagcctaa aaaacatgtt catgcctggc ccggcctccg tttcagaaca ccaggtgttc
     6781 tgcgcgcaca atcaaagaca tacccgaatt cagctggacg cggacgccgt ctttggtgat
     6841 ttctaatacg gtggcatcca tcgcgttttg acccgctttc accttcaggg cttgtccgac
     6901 agtcagagct gaaatgtcag aaaccggggt gtgctgttct tcgcgaggtg cttttactgt
     6961 ttttggcgct ttctctaccg gcttttgcgc acgaggttta cgttcagcgc cttctttgcg
     7021 gcgtggcgtg gtcggacgtg gcttgcgttc gcggcgcggt gcgtcttctt tctcaccagc
     7081 agctgcggca gcttcgcgtt ttttcgcttg ctgttcagca cgctgtgcct gaacacgcgc
     7141 tttcgcttct tcaagctgct tgcgagcatg ctctacatgt tgctcgtcca gctcaccgca
     7201 tgggttgccg tcaagatcga cacgcgttgc gccgggttta acaccgtaaa gataacgcca
     7261 gctcgaagtg tagagacgta aagcggatcg taattgcgtt ttgctcaggt tcatttcccc
     7321 ggcaacacga tcgaccaaat cctgaaaaat accgattttc agcggacgcg cttcaccttc
     7381 cgcactgaaa cagtggggaa aacgttcggc cagaaacgcg attacttctt tactgctatt
     7441 caacttaggt tgattttcca tgaaatttcc tgattacaac ggacgtagcc aacaagcgca
     7501 ggcatgaaca ggcgtcatta taatgacgct accagtaaat gctacgttat ccgttgatta
     7561 tcctgcgacg ctcgcaaaga attttttgta atccgtcgtt gcaagcactt tttcaagctg
     7621 tgccacaagc tgacgtaagc cttgctcgtc ctcgtctgta aagcgaccga agacggtact
     7681 atcgatgtca agaacaccaa taatctgatt tttcaccacc agcggcagaa caatttcaga
     7741 attactcgcc gcatcacagg caatatgccc gtcaaacgcg tgaacatcct cgatacgctg
     7801 cacttgattg cgggcaaccg cagtgccgca caccccgcgc ccgacgggta tccggacaca
     7861 ggcaattttg ccctgaaatg gtccgagtac cagtgtatcg tcctcaagca aataaaaacc
     7921 tgcccagttt acgtcagtga gacgctcgta taacaacgca ctggtgttcg caagcgttgc
     7981 cagaaaactg gtttctcccg ccatcagcgc gttaaagtcg cgatttaaat ccgcgtaaaa
     8041 ttctgttttg ttcattatat aatcacttgt ttgtcttacc tggaactgcc agcctattaa
     8101 aataagcatt aaatgcgtta atgctcaaga tcattcccat catgggttaa gattaatgtt
     8161 aattcttatt acatttggca cgtcatggct cttaacacac cacaaattac gccgacaaaa
     8221 aagataacag tgagggcaat cggcgaggaa ctgccgcgtg gtgattacca acgttgcccg
     8281 caatgtgaca tgctgtttag cctgcccgag ataaattctc atcagagtgc ctattgtccg
     8341 cgctgtcagg caaaaattcg cgacgggcgc gactggtcgc taacgcgcct ggcggcaatg
     8401 gctttcacca tgctgttgct gatgccgttt gcctggggcg aaccgctgtt gcatatctgg
     8461 ctgttaggta ttcgtatcga cgccaacgtc atgcaaggca tctggcaaat gaccaaacag
     8521 ggcgatacga taacgggggc gatggtcttt ttctgcgtta ttggtgcccc cctcattctg
     8581 gtgtcctcca tagcatattt atggtttggt aaccgactgg gaatgaattt acgtccggta
     8641 ctgctgatgc ttgagcgact taaagagtgg gtaatgctgg atatctacct ggtcggcatt
     8701 ggcgttgctt ctataaaggt acaggattat gcccatatcc aggcgggtgt cggcttgttc
     8761 tcttttgtgg cgttggtgat tttaacgacg gtgacgttgt cacatcttaa tgtcgaggag
     8821 ctgtgggagc gattttatcc gcagcgcccc gctacgcgta gggacgagaa acttcgtgtc
     8881 tgtcttgggt gccattttac cggctatcct gatcagcgtg gtcgctgccc gcgttgccat
     8941 atcccgctac gcctgcgtcg ccgtcatagt ttgcaaaaat gctgggcggc gctgttagcg
     9001 tcaatcgttt tgttgttacc tgccaacctg ttgcctattt ctatcattta tctgaacgga
     9061 ggacggcagg aagatacaat tctttccgga attatgtcgc tggcaagtag caacattgcg
     9121 gttgcgggaa tcgtgtttat cgccagtatt ctggtaccgt ttactaaagt gatcgtcatg
     9181 ttcactttac tgttgagcat tcattttaaa tgccagcaag gtttacgcac acgcattctg
     9241 ttactgcgga tggtgacctg gattggtcgc tggtcgatgc tcgacctgtt tgtcatatct
     9301 ttaaccatgt cgctgattaa tcgcgatcag atcctcgctt ttactatggg accggctgcg
     9361 ttttatttcg gcgcagcggt aattttgact attcttgctg tggaatggct ggacagccgc
     9421 ttactttggg atgcacatga gtcaggaaac gcccgcttcg acgactgaag cgcagattaa
     9481 aaataaacgc cgtatctcac ctttctggct gctgccgttc atcgcgctaa tgattgccgg
     9541 ttggctgatt tgggacagtt atcaggaccg gggtaatacc gtcaccatcg actttatgtc
     9601 ggcggatggt attgtcccgg gccgtacgcc tgttcgttat cagggcgttg aagtcggaac
     9661 agtgcaggat atcagcctca gcgacgatct tcgtaagatt gaagtcaagg tcagcatcaa
     9721 gtccgatatg aaagatgcgc tgcgcgaaga gactcagttc tggctggtga cgccaaaagc
     9781 atcgttggca ggtgtctccg ggctggacgc cctcgtcggt ggtaactata tcggcatgat
     9841 gccaggtaaa ggtaaagagc aggatcactt tgtcgcactc gatacccaac cgaaatatcg
     9901 actggacaat ggcgatctga tgatccacct gcaagccccc gatctcggtt cgctgaacag
     9961 cggttcattg gtctatttcc gcaagatccc tgtgggaaaa gtctacgact atgccatcaa
    10021 tcccaacaag caaggcgtgg tgattgatgt cctgatcgag cggcgtttta ccgacctggt
    10081 gaaaaaaggt agccgtttct ggaacgtttc cggcgttgat gccaacgtca gtatcagtgg
    10141 cgcgaaggtg aaactggaaa gtctggcggc actggttaac ggtgcgattg ccttcgattc
    10201 acctgaagag tcgaaacctg ccgaggcgga agataccttt ggtctgtatg aagatctggc
    10261 ccacagccag cgcggcgtaa taacaaaact ggaactgccg agtggggcag gattaaccgc
    10321 cgactcgacg ccattaatgt atcagggact ggaagtcgga cagctaacta aactggattt
    10381 aaatcctggt ggtaaagtca ctggggaaat gaccgttgat cccagcgtcg ttaccctgct
    10441 tcgtgaaaat acccgcatcg aattacgtaa tccgaaatta tcccttagcg atgccaatct
    10501 cagcgccctg ctgactggca aaaccttcga gttggtaccc ggcgatggcg agccacgcaa
    10561 agagttcgtt gttgtgccag gcgaaaaagc actgctgcat gaacctgatg ttctgacgct
    10621 gaccctgacc gcgccggaaa gttacggtat tgatgcgggt cagccgctca ttcttcacgg
    10681 cgtgcaggta ggccaggtta tcgatcgtaa actcaccagc aaaggcgtca cctttaccgt
    10741 cgccatcgag cctcagcatc gcgaactggt aaaaggcgat agcaaatttg tcgtcaacag
    10801 ccgtgtcgat gtgaaggtgg ggctggatgg cgttgagttt ctcggtgcca gcgcctcaga
    10861 atggatcaat ggcgggatac gtattctgcc gggcgataaa ggtgagatga aagccagcta
    10921 tccactgtat gccaatttgg aaaaagcgct ggagaacagc cttagcgatt tacccaccac
    10981 aaccgtgagt ttgagtgcag agacgctgcc ggatgtgcag gcaggatcgg tagtgctgta
    11041 ccgtaaattt gaagttggtg aagtgattac cgtgcgtccg cgagctaacg cgtttgatat
    11101 cgatctgcat attaagccgg agtatcgcaa ccttctgacc agcaatagcg tgttctgggc
    11161 agaaggcggg gcgaaagttc agctgaatgg tagtggtctg accgtacagg catccccgct
    11221 ctccagagca ttaaagggag ccattagctt cgacaacctc agcggtgcca gcgccagtca
    11281 gcgtaaaggc gataagcgta ttctgtatgc ttccgaaaca gcggcccgtg cggttggcgg
    11341 gcagattacg cttcacgctt tcgatgccgg aaaactggcg gtcgggatgc caattcgcta
    11401 tctcggtatt gatatcgggc aaatccagac gctggatctg attaccgcac gcaatgaagt
    11461 acaggcaaag gcggtacttt acccggaata tgtccagacc tttgctcgcg gtggtacgcg
    11521 cttctcagtg gtcacaccgc aaatttcggc agctggcgtt gagcatcttg atactatcct
    11581 ccagccgtat atcaacgtcg aaccaggccg gggcaatcct cgccgcgact ttgaattaca
    11641 agaggccacc attactgatt cgcgttacct ggatggctta agcattattg ttgaagcgcc
    11701 ggaagccggt tcgttaggca tcggtacgcc tgtgctgttc cgtggtctgg aagtcggtac
    11761 ggttacagga atgacgctgg ggacattgtc agatcgcgtg atgattgcga tgcgcatcag
    11821 taaacgctat caacacctgg tgcgtaacaa ttccgtcttc tggttggcat cgggttacag
    11881 tctggacttt ggtctgacgg gcggcgtagt gaaaaccggc acctttaacc agtttatccg
    11941 tggcggcatc gccttcgcca cgcctccggg gacgccactg gcaccgaaag cccaggaagg
    12001 caagcacttc ctgttgcagg aaagtgaacc gaaagagtgg cgtgaatggg gtactgcgct
    12061 tcccaaataa tgcccactgc tccggcgtgc ctgcgccgga gcgtttatgc taaactgcgc
    12121 gcctgttttt ttgccagtgg tatatgctcg tggcccaaca caccgtttat ttcccggacg
    12181 cctttctgac gcaaatgcgc gaagcgatgc cttcgacgct ctcttttgat gattttcttg
    12241 ccgcctgtca gcgcccgttg cgccgcagta ttcgcgttaa tacgctgaaa atctccgttg
    12301 ctgatttcct gcaattaacc gctccttatg gctggacgct tacgccaatt ccgtggtgtg
    12361 aagaaggttt ctggattgaa cgcgacaatg aagatgcatt gccattgggt agtaccgccg
    12421 agcatttaag cggcctgttt tatattcagg aagccagttc aatgttgccc gtcgccgcct
    12481 tgtttgctga cggtaatgca ccacagcggg tgatggatgt cgctgctgcg ccaggctcca
    12541 aaacgacgca aattgccgca cggatgaata acgaaggggt aatccttgcc aatgagtttt
    12601 ccgccagtcg ggtaaaagtg ttacatgcca atatcagccg ctgtggcatc agtaatgttg
    12661 cgctcacaca ttttgatggc cgcgtgtttg gtgcggcagt gccagaaatg ttcgatgcca
    12721 ttttgctgga cgctccctgc tccggcgaag gcgtggtgcg taaagatccc gatgcgctaa
    12781 aaaactggtc accagaaagc aatcaggaaa tcgcagctac ccaacgggag cttatcgaca
    12841 gcgcctttca tgcattacgt cctggtggta cgctggttta ctcgacctgt accttaaaca
    12901 gggaagaaaa cgaagtcgtt tgcctgtggc tgaaagagac ttaccctgac gcagtagagt
    12961 ttttaccact tggcgatctc ttccctggtg caaacaaagc gctgaccgag gaaggctttt
    13021 tgcatgtttt cccacaaatt tacgactgcg aaggcttctt cgttgctcgt ctgcgtaaaa
    13081 ctcaggccat tcccgcctta cccaccccaa aatacaaagt gggcaatttc ccgttcagcc
    13141 cggtgaaaga tcgcgaagcc ggacaaattc gtcaggcggc tgcaagtgtt ggtttaaact
    13201 gggatgaaaa tctgcgcctc tggcagcgtg acaaagaact gtggttgttc ccggtgggca
    13261 ttgaagccct gatcggtaaa gtccgatttt ctcgcttggg gattaaactt gccgaaacgc
    13321 acaacaaagg ttatcgctgg cagcatgaag cagttattgc ccttgccacc cccgacaatg
    13381 tgaacgcttt tgaactgaca ccgcaggaag cggaggagtg gtatcgcggg cgcgatgttt
    13441 acccgcaagc cgcgccagtg gcggatgacg tgttggttac tttccagcat cagccgattg
    13501 gtttagccaa acggattggt tcgcgactga aaaacagcta cccgcgtgaa ctggtgcggg
    13561 acgggaaact ttttaccagt aacgcatgac agcgcacaaa aaaagcgcac tttttgactg
    13621 gcacattcgg cggcctcaac taggctgaaa aatggtgcga tcggactggt cgtaccacaa
    13681 tcggcagcta aatggagagc acgaagatga aaaccagtgt gcgcataggc gcttttgaaa
    13741 tcgacgacgg cgaattacac ggtgaatcgc cgggtgatcg aacgttaacc attccttgta
    13801 aatctgaccc cgatttatgt atgcaactgg atgcctggga tgctgaaacc agtatccctg
    13861 ccctgctaaa tggcgaacac tctatccttt accgtacccg ttacgatcaa caatctgatg
    13921 cctggattat gcgtcttgcc tgatccaaaa agaacccgtc ggcatggcgg gttatttgtc
    13981 ctggttattc ccccgttgta aaatctctcc taaacttaac ggtacggcac cacacttcgg
    14041 ggatgaaatg ttcgcgctgg tactttttgt ttgctacctg gatggcggtt gtgaagatat
    14101 tgttgtggat gtctacaaca cggaacagca gtgtcttcat tctatgagcg atcaacggat
    14161 ccgccagggc ggttgttttc cgattgagga ttttatagat ggtttctggc gacctgcgca
    14221 ggagtacggt gatttttaat tattgcaatt gcacaagagt cagttcgccc ccaaaggcag
    14281 caccggtatc aatataatgc aggttgccaa tatccacgcg atgtcgcaac ggtgtatgac
    14341 caaaccagaa atgatcagca cctgtaattc cctgcccttt tgggcgttca cctaatcgtg
    14401 agcggctcca caagacctga tgcaaatcaa cgtccttttg ccattcataa acatcatctg
    14461 gataatcggc atgagcaata acatgtttgc cggtgcggct gtgtacttca agaataaagg
    14521 gcaaatgctg acatttttcc agcgccgttt tcgcttgttt ctgttgatta tctgccagcg
    14581 caataaacca gtcgccgcca ttcatcaacc acaaagacat ctgctgggat gccagcgcat
    14641 ccatcgccat ctgttcatga ttgcctctta ccgcacgaac ccaatgttgt tccagtaact
    14701 gcagacaacg taaactttgc ggcccacgat cgataacgtc tcccactgag ataagtaaat
    14761 ctcgccacgg atcaaaacga caatgccata atttgcggcg caactgctca agacaaccgt
    14821 gtatatcgcc agaaagccag atatgtcgcc attgatgacc cgcaattctc tgataaacgg
    14881 gcgcaggctg tttcatcaat attttcctcc cgcgctaaag atcacataat cttaacaaga
    14941 atgttaaaaa acgctggact cagacagtag agtgtgtgtt atggttgact ataaagtcag
    15001 cgaaggaaat gcttctggct tttaacagat aaaaagagac cgaacacgat tcctgtattc
    15061 ggtccaggga aatggctctt gggagagagc cgtgcgctaa aagttggcat taatgcaggc
    15121 ttagttgcct tgccctttaa gaatagatga cgacgccagg ttttccagtt tgcgtgcaaa
    15181 atggtcaata aaaagcgcgg tggtcatcag cttaaatgtt aaaaaccgcc cgttctggtg
    15241 aaagaactga ggcggttttt ttattggaaa tcaaaaggct attttaggta attaacagag
    15301 tttttcagct cgttctataa acggtgccag actcattttt tcgccgggat tgttaggatc
    15361 atcaatctga atcaccgaaa tgggttgggc tttagtcttc ccactggcaa cttccttttg
    15421 tgcgatatcg tttaaaggat actgcacgag ggtacttggg ttgatgacat acaaagcatt
    15481 acccggtcgg caagtcagca tcacctcttc gcgattaaac gcccatttgt ctttacccac
    15541 ttcaaaacgg ctgacggtaa tcacctgcgg tgccgccagc gccgctgcag aactggtgag
    15601 taacagaaac gccagaatac tttttttcat cattttcgta atccatcaaa aaggttcgag
    15661 agtcgcaagc aggctgatga tcaccagcac taccgcacct atcgcccatt cgagtttagt
    15721 catccacaca aaccagggtg ccgcacgatc ttcatcctgc ctcatgcgcg gtacaagaac
    15781 ataacgatta gccagcgcaa tgaccaccat aatcatcacc aggatggctt tgagcaataa
    15841 gagttggccc cagtaagtcg taagcgtggg gggaaatccg gtaatcaaca atgcattaag
    15901 cacgccgctt gccagtacgc cgatcaccgc aaaatgcccg caccaggaaa aacgcatcag
    15961 cgcctgaata gtctggtgtc gccaacggcc tttgatgagt tgtatacacc agagcaccgg
    16021 cagtaatccc ccaaaccacg ccgccgcaca aatcaggtga atcgcgtgat tagtctgatg
    16081 gattttctcc gttacccctt cattcagcgt cgcatgcccc actcccgcca gcagaaaaaa
    16141 ttgcgcggta gtgagcataa acagcaaacg tggcatattc cgcggttgca taagggcgac
    16201 gatcaacgtt acgagggcga gaacaatttg ccataaccag acgccaccaa actgcgtttg
    16261 taaaacagcc tgccaaatgt ttggcgaaaa tacatctgtc catcccgttc ccatcaaccc
    16321 gccctgaacg gcgagcattg cagtggcact gatcaaactc cagacggcag cgtgctgttg
    16381 taaacgcaga aaacgcttcg ccagcaaacg acgaatcgtt aagggggcca gccaggcacc
    16441 gtacattgcg aagccaaaaa ccagcatcag cgaggtgaaa tggataaatc gcagcgcgat
    16501 ccaggtaaac gccagcatga tttatttcac gctaaaggtg tagtgtcctt tcgttttatg
    16561 cccgtccacc gaaacaacat gccagtcaac ggtgtaggtt ccgggtttca gcgaatcggc
    16621 cagtggaaca atcagttgct tttggtcctg ctcatttcgc ttcgccggta atgttttaat
    16681 attttcgttt tttggccccg tgatttttgc accactgaat cctgtttcca caccttccga
    16741 gaagtttaaa gtgattgcct gcggtgcagc tgtcacttgc gcgtttgccg caggatactg
    16801 atgcgttaaa tgcgcatgtg cccagacgga aggtgtcacc aacgaagtgg tcaggattgc
    16861 cagcgcgtag cgaagggagc gtgcagttga agccatatta tctattcctt tttgtaataa
    16921 cttttttaca gagcataacc ttgtctaatg tctgagtcga ggatcatcaa ttccggcttg
    16981 ccatcctggc tcactcttag taacttttgc ccgcgaatga tgaggagatt aagaatgctg
    17041 aagaatctgg ctaaactgga tcaaacagaa atggataaag tgaatgtcga tttggcggcg
    17101 gccggggtgg catttaaaga acgctacaat atgccggtga tcgctgaagc ggttgaacgt
    17161 gaacagcctg aacatttgcg cagctggttt cgcgagcggc ttattgccca ccgtttggct
    17221 tcggtcaatc tgtcacgttt accttacgag cccaaactta aataaaactt atacagggtt
    17281 acactttctt acataacgcc tgctaaatta tgagtatttt ctaaaccgca cccataattt
    17341 gcagtcattt tgaaaaggaa gtcattatgt cgttctggaa agttgcagca gcgcaatatg
    17401 agcctcgtaa aacctcactc accgaacagg tagctcatca tctggagttt gtgagggccg
    17461 ccgccaggca acaatgtcag ctgttagttt ttccatcgct ttctttactg gggtgtgatt
    17521 attcgcgacg tgcccttcct gccccacccg atctctcact gttagacccg ctttgttatg
    17581 ccgcaacgac ctggcgaatg accatcattg ccggccttcc cgttgaatat aacgatcgct
    17641 ttattcgtgg aattgcggtg ttcgcaccgt ggcgaaaaac gcctgggatc taccatcaga
    17701 gtcatggtgc atgtctgggc cgtcgttcca gaaccatcac ggtggtcgat gaacaaccgc
    17761 aaggtatgga tatggacccg acctgttcac tgtttacgac agggcaatgt ctgggagaac
    17821 ccgacctgct ggcgtcggcc cgtcgcttac aatttttttc acatcagtac tcgattgccg
    17881 tgctgatggc aaatgcccgt ggtaacagtg cactatggga tgaatatggt cgtctcatcg
    17941 ttcgcgccga tcgtggttca ttattgttag tcggtcagcg ttcatcacag ggttggcaag
    18001 gcgatatcat tccattacgc taggcttttt cggcctggag catgccatgt tgcgcattat
    18061 cgatacagaa acctgcggtt tgcagggagg gatcgttgag attgcctctg ttgatgtcat
    18121 tgacggaaaa atcgtcaacc ccatgagcca cctggtgcgc cccgatcgtc ctattagtcc
    18181 acaagcgatg gcgattcatc gcatcaccga agccatggtc gccgataaac cgtggattga
    18241 agatgtgatc ccacactatt acggtagtga atggtatgtc gcgcataacg ccagctttga
    18301 ccgccgcgta ctgcctgaga tgcccggtga gtggatttgc actatgaaac tggcccgtcg
    18361 tttgtggcca gggatcaagt acagcaatat ggcgttatat aaaacacgga agctcaatgt
    18421 acagacgccg ccgggcctgc atcatcaccg cgcgttgtat gactgttata tcaccgccgc
    18481 gttgcttatc gatattatga acacctccgg ctggacggca gaacagatgg ccgatatcac
    18541 cggacgtccg tcgttgatga cgaccttcac ctttggcaaa taccgtggca aagcggtttc
    18601 cgacgttgcc gaacgcgatc cgggctatct gcgctggtta tttaataacc tgggcagcat
    18661 gagcccggag ctgcgtttaa cactgaaaca ttatctggaa aatacttaat ccgcaggcgt
    18721 agcgggtaat gttccctgcg ccagcgcgac cagaaaagca tattccatcg ctacgccttc
    18781 gtacgattta aagcgaccag atttaccgcc atggcctgag tccatgtcgg tacagagcaa
    18841 taaaagatgg ttatcggttt tcagctcgcg caatttagcg acccattttg ccggttccca
    18901 atattgcacc tgagaatcgt gcaaaccggt cgttaccagt aaatgcggat aagcctgtgc
    18961 ggtgacgttg tcatacgggc tgtagctttt catgtactcg taatattgcg gatcctgcgg
    19021 gttaccccac tcttcaaact caccagtggt aagaggaatt gattcatcaa gcatcgttgt
    19081 tacaacatca acaaacggta cctgggcgat aacgccgtgg aataattccg ggcgttgatt
    19141 aattgcaacg cccatcaaca tgccccccgc actcccgccc atcgcataac aaagcgaagg
    19201 agagccatag cccagtttta acaatgcatc gcaggcatca agataatcat taaacgtatt
    19261 tttcttcttc agaaattttc cgtcttcgta ccattgttgc cccagctcac caccgccgcg
    19321 aacatggaca atggcgtaga caaagccacg atctaacaaa ctcaagcggc taaaactgaa
    19381 atcggcatca atacttgcgc cgtaagaacc atagccatac accagcaacg ggttgtgtcc
    19441 tttgcgaaaa tgtttgcgat ggtagaccaa cgaaaccgga acttcgacgc catcacgggc
    19501 gactatccac aggtgttcac tgcggtaatt cgccgcatca aaaccgggca cttctgtttg
    19561 ttttaataca cgacgctcac cggtatccat atccagttca aacaaagtgt ctggtgtggt
    19621 catggaagaa taaccataac gcaatcgcgc ggtttcaggt tctggattgt aggcaatcca
    19681 ggtcacatag gctggatcat caaaggcaat accaatgact tcccgggtct tgcggttaat
    19741 ttggcgcaaa ctggttaacc cgcgctgacg ctcttcaacc accagccagt cggtaaacag
    19801 cgtaaaccct tccagcatga tgttttcgcg tggcggaatt aactcttccc actgttgctc
    19861 atcacgcata cgggtacggt ataagccaaa gtttttgccg tggcggttgg aacgtagata
    19921 aaaacgatgc tggtagtgat caaggctgta ttcgtgatct ttgcggcgcg gcagaaaaac
    19981 aaacggctcg gcatcggcca tttccgcgtc cagcaggcga acttcactgg tagtggcgct
    20041 ggccaaatga atgactacat agtgcttcga ggtcgtttta tgcaggctga cgtaataggt
    20101 atcgtctttt tcttcgtaga tcagtttatc ttgcgatgct ggcgtaccga tggcgtgacg
    20161 ccagacctga taaggcagca gcgtcaccgg atgcttgcga acatagtaga aagtccagga
    20221 gtcatttgcc cagacaaagc tgggttcaac gttatccagc agttccgggt accagttacc
    20281 agtttccaga ttacgaaaac gaatgccgta ctggcgtcgg gaaagaaaat cttctgccag
    20341 cgccataatg gtgttatcgg gcgtaatcgc cattccgccc atcgaataaa actcactatg
    20401 agctgcgcgc ttattggcat cgagcaatgt ttcccactca tcccactctt cactgaatgc
    20461 cgattgacgc tggtagatag catattcaca gcctggttca taaatatgcc gatagcggta
    20521 gccatttttg atgtagggcg cagaaacttc tcgttgcgga atgcggtcga tgatttcctt
    20581 taagatgcga tcctgcaagg cttgttgtga ggccatcacc cgatgaccgt aactattttc
    20641 ttgttgcagg tagtccagaa cttccggctg agaacgcgta tcgtcccgca gccagtagta
    20701 attatcgatt cgcgtatcgc catgaagcgt catggcgtgg ggaatgcggg cggcttttgg
    20761 tagcatgtta ttgttctttc tggttgaaac atcttataag ggtggcaaaa ctcaccgggg
    20821 atgcaagcga aacaggggag tcattgctta gatgatgaca ggtaatggcg cggatatcga
    20881 atgttatgca gacagagaaa atcagcctgt tcaaatggct gtgcgattct ggatagcccg
    20941 aaatagtcaa cttcaggcta tccagagagc ggaattattc cgccaaagtg cgtttttgct
    21001 gttcgagatc gcgttcaatg ccgtcacgaa catcctgggg gattttcagc gcgtcaccca
    21061 gtgcattcag gtaactgcgt tccataaaat ggtcaatatc aatagccgcg caactcagga
    21121 aatagatttc cagcgcctct tcttcattgc ggaccccggt agccaggcgt tgtggatcca
    21181 gcggttgttc gattgcctgc tcaatgagta cacgcccctg ctcttccacg ccggcttcac
    21241 gcaattgctg gtcgattgcc gcacgttctt tggcatcaat atgaccatca cttttagcgg
    21301 caaagaccag cgcaaggatc aaacgttctg tacgctcatc cagcggcgta ctttgcgcgc
    21361 caaactgcgg ttcgtcctga tgcgccgcgc gaattttatc tttgtattta ttccacagca
    21421 ccgtacccgc taccgctccg ccgccaacca gtaacgcgtt ggtgccatat ttcgtaagaa
    21481 gtttacgtgc tgatttattt gcgaccagca gcccagccag tccgcctaat gcgcctggca
    21541 ctaacagttt gcccaatccc tgatccgcag acgaggaggt agaagaactg ctttgcccaa
    21601 gcagggattg cagttgattt aaccagttag ccatatttgc tcctcaataa ccatttttag
    21661 tgcctgtagc atagcggatg aggatgtcag aaaatgtata tcgagacaaa agatgcgcaa
    21721 ataagcgggg cggtaggccg ttattcaaag aaattcgcgc caggtaaggt atttactgta
    21781 tatcaggtga taagggtatt ttaggtgaaa gtagtttgtc gttttgagtg gcattgtttg
    21841 atgctgattg cccgatgcga cgctgttgcg tcttctcagg cctacgattg tggtgcgttc
    21901 tggggcggac aaggcactcg cgccgcatcc gccaacggtc aatcgaatta tcagaagcca
    21961 ttaacgccgc tgatattccg ccattcccgc tttgcagtcc acgctgacct ggtaatgaat
    22021 atcggcactt ttaccacgca cggtcagcgg tactgaccat ttatcatctt taccctgaat
    22081 gtcctgcaaa ctgacccaag ccacgggatc ggcctgaccg acaatttttt gatcatctgc
    22141 ccagcgcgcc acgcgatttt gttgataatc acgttttacg ctcgcggcaa ttccggcagc
    22201 atccagacct tcacactttg ggaaagtgac cgacttgctg gtttcattat tggcagcgaa
    22261 aactgatgcg caggcagaaa ccaacaacag ccctaaaaac gcccctcttt ttttcatgtt
    22321 tttctccata gcacaatgat tcaggagaaa gcatggtaca aattgtcagg agcgcaagtt
    22381 gcttcaggcc gcgtgtgagg catcttcctc ttcggattca gcaccgacga cctgtgggga
    22441 cggtaatttg ccggttttca gaatggtgct cagcacatct ttttgttctg ccagccatag
    22501 cgaaagggct tcacgttgct cgtcttccat ttgcactgga gaatttgtca gccaggtgtc
    22561 aagcagatcc gccgtatcaa gcattttatc ataagcatcg gcttcctttt tgctggtaaa
    22621 cgacattttc tcttcgccct cacgaatgac tacgtattta acttcaaccg ccatttgcag
    22681 cctctcataa taactgtgat tttatacagt atatttcttt tcggttgaga aatcaacatc
    22741 agcaataaag acacgcgcaa acgttttcgt ttatactgcg cgcggaatta atcaggggat
    22801 attcgttatg acgttattag gcactgcgct gcgtccggca gcaactcgcg tgatgttatt
    22861 aggctccggt gaactgggta aagaagtggc aatcgagtgt cagcgtctcg gcgtagaggt
    22921 gattgccgtc gatcgctatg ccgacgcacc agccatgcat gtcgcgcatc gctcccatat
    22981 cattaatatg cttgatggtg atgcattacg ccgtgtggtt gaactggaaa aaccacatta
    23041 tatcgtgccg gagatcgaag ctattgccac cgatatgctg atccaacttg aagaggaagg
    23101 actgaatgtt gtcccctgcg ctcgcgcaac gaaattaacg atgaatcgcg agggtatccg
    23161 tcgcctggcg gcagaagagc tgcagctgcc cacttccact tatcgttttg ccgatagcga
    23221 aagccttttc cgcgaggcgg ttgctgacat tggctatccc tgcattgtaa aaccggtgat
    23281 gagctcttcc ggcaaggggc agacgtttat tcgttctgca gagcaacttg ctcaggcatg
    23341 gaagtacgct cagcaaggcg gtcgcgccgg agcgggccgc gtaattgttg aaggcgtcgt
    23401 taagtttgac ttcgaaatta ccctgctaac cgtcagcgcg gtggatggcg tccatttctg
    23461 tgcaccagta ggtcatcgcc aggaagatgg cgactaccgt gaatcctggc aaccacagca
    23521 aatgagcccg cttgcccttg aacgtgcgca ggagattgcc cgtaaagtgg tgctggcact
    23581 gggcggttat gggttgtttg gtgtcgagct atttgtctgt ggtgatgagg tgattttcag
    23641 tgaggtctcc cctcgtccac atgataccgg gatggtgacg ttaatttctc aagatctctc
    23701 agagtttgcc ctgcatgtac gtgccttcct cggacttccg gttggcggga tccgtcagta
    23761 tggtcctgca gcttctgccg ttattctgcc acaactgacc agtcagaatg tcacgtttga
    23821 taatgtgcag aatgccgtag gcgcagattt gcagattcgt ttatttggta agccggaaat
    23881 tgatggcagc cgtcgtctgg gggtggcact ggctactgca gagagtgttg ttgacgccat
    23941 tgaacgcgcg aagcacgccg ccggacaggt aaaagtacag ggttaaaccc ggcaaaaaaa
    24001 cgctacaaaa atgcccgatc ctcgatcggg cattttgact tttacagctt agcgccttct
    24061 acagcttcac gcgccagctt agtaatgcgg tcgtaatcgc ccgcttccag cgcatctgcc
    24121 ggaaccagcc aggaaccacc gatgcacagc acgcttttca gcgccaggta gtcacggtag
    24181 ttagccggag aaataccacc cgtcgggcag aaacggacct gggagaacgg acccgcgatc
    24241 gcctgcaggg ctttcacgcc gccgttagct tcagccggga agaatttgaa ctctttcaaa
    24301 ccgtagtcca tacccagcat cagttcggaa acagtgctga tccccggaat cagaggaata
    24361 gtcccttcgg tagcagcttt cagcagcggc tcggtcagac ccgggctaat tgcgaactgt
    24421 gcacccgctt cagtgacttc tgccagctgc tgtggattca gcaccgtacc ggcacccaca
    24481 atcgcttcag gcacttcttt ggcgatagca cggatagcgt caactgcaca ctcggtacgc
    24541 agagtcactt ccagaacgcg caccccacca gcaaccaacg cttttgccat cggcaccgcg
    24601 tgttccagtt tttttaccac gataaccggt acaaccgggc cggtggtcag gattgattct
    24661 gcacttgttt tccagttttt catcagagtt ttctctcgcc tgattacaaa tttgtcgtct
    24721 taaaaagtga tacaggttgc gccctgttcg gcaccggaca gtttttcacg caaggcgctg
    24781 aataattcac gtcctgttcc cacgcgtgac gcgctcaggt caggaatgtg cggttcgcga
    24841 gcagccagtt ccgcttcgtc taccagcagc gtcagttcgc ctgtctgtcc attcacacga
    24901 atgatgtccc cgtcgcgcac ttttgccagc agcccgccat cgtaggcttc tggtgttacg
    24961 tggatagctg acggcacttt acctgaagcg ccggagagtc gtccatcggt aactaacgca
    25021 attttgaaac accggtccaa taatacacca agtggcggca tgagtttatg taattctggc
    25081 attccgttcg cttttggccc ctgatgacgg acaacaacga cacaatcgcg gtccagcaaa
    25141 cccgcttcaa aggccggcat aacgtcatgc tggctttcaa aaacaaccgc tggcgcttca
    25201 atcacctggt tctcaaccgg cacggcagag gttttcataa ccgcacggcc caggttaccg
    25261 cttaacactt ttgtcccacc atgatgagag aaaggttgtt cgaaggaagc gatcacattg
    25321 ctgtcgagtg atttttccgc cccttcccgc cagtccagtt caccattatt cagccatggt
    25381 tcaagggtat aacgagacag accaaagcct gccaccgtat tgacatcttc atgcagcagg
    25441 cctgctttga gcagttcacg caccagaacc ggtacgccac ctgccgcctg gaagtggtta
    25501 atatcggccg gaccgttcgg gtagagacgt gccatcagcg gtacaacatc agaaaggtca
    25561 gagaagtcat cccagttaat ctgaataccg gccgcgcgcg ccatcgccac caggtgcatg
    25621 gtgtggttag tggaaccacc ggtcgccagc agtgcaacga taccgttcac caccactttc
    25681 tcatcgatca tcttaccgat cggcatccat tcattaccat taccggtcat gcgtgtaacc
    25741 tgacgcgcag cggcagcggt caaagcatcg cgcagcggag aatccggatg aacaaaagaa
    25801 gagcctggca actgcatccc cataaactcc accaccatct ggttggtgtt ggcagtaccg
    25861 tagaaagtac atgttcccgg cgcatggtaa gacgcggctt ctgactccag taaggccatg
    25921 cggtccactt taccttcggc ataaagctgg cgaatacgca ctttttcttt atttggcaaa
    25981 ccgcttgcca tcggtccaga cggcacaaac accgcaggca aatgaccaaa cgacagggct
    26041 gccatcgtca gacccgggac aatcttgtcg cacacaccga ggaacagagc accatcaaac
    26101 atgttatggg acagccccac cgccgcagac atcgctatca cttcgcggct tagcagcgac
    26161 aattccattc catcctgccc ctgggtgaca ccatcacaca tcgccggaac accgcccgca
    26221 acctgaccaa ccgcattcgc ttcatgcagg gctttacgaa tgatttctgg atagtgttca
    26281 taaggctggt gcgcggagag catgtcgtta taggaggtga tgatggcgat attgttacgc
    26341 aacatgcttt tcaaagaggc tttgtcttct ggctggcagg cagcgaaacc gtgtgccagg
    26401 ttaccgcatg ccaactgcga acgatgaacg gtcgacgttt tcgcttgttc tatccgggcg
    26461 agataagcag agcgagtctc gcgcgaacgt tcaatgattc gatttgttac gcgtaacaat
    26521 tgtggattca taaaggctcc tgaaattgag ttgtcagagc aggatgattc acaacgcgtt
    26581 tcattcagag gatttatgac tgaaacgcct gtaaccggag ctcatagggc aaaaacgttt
    26641 cagtcagtgt aataaaaaaa gcctcgtggg tgaatccgca cgaggcctga aagtgtaaaa
    26701 attgttctac aatctgcgca agatcatgtt accggtaaaa taaccataaa ggataagcgc
    26761 agatattact caaactcatt ccaggaacga ccatcacggg taatcatcgc caccgaggca
    26821 acgggtcccc aggttccggc ctgatacggt ttcggcgcat cattgtccat cgcccacgcc
    26881 tcagtaatgg agtctaccca tttccaggct tcttccactt catcacgacg tacaaacagt
    26941 gcctgaatac cacgcatggt ttccagcagc agacgttcat aggcatccgc cagatgcgtc
    27001 tgattaaagg tttctgaata gctcagatcc agcttggtga tttgcaggtt atgtttgtgg
    27061 tcaaggccag gaactttatt cagtacctgg atatccacgc cttcatcagg ttgcagacgg
    27121 atagtcagtt tattctgcgg cagatcctgc cacgactctt taaacagatt cagttcaggt
    27181 gttttgaaat agaccacgac ttcagaacat ttggtcggca gacgtttacc agtacgcagg
    27241 tagaatggca caccggccca gcgccagtta tcaatgtcga cgcggatcgc cacgaaggtt
    27301 tctgtattgc tgctcttgtt cgcgccctct tcttccagat atcccggcac ttttttgccc
    27361 tgggcgaagc ccgcagtata ttgcccgcgt acggtttttt cgcgtacgtt ggagcggtcg
    27421 atgcggcgca gggacttcag tactttcact ttttcatcgc ggatgctgtc tgcgctcagg
    27481 tcagatggcg gagacatcgc aatcatgcag agaatttgta gcaggtggtt ctgaatcatg
    27541 tcacgcatct gaccggcttt atcaaaatag ccccagcgcc cttcgatccc cacttcttct
    27601 gccacggtaa tctcaacatg atcaatggtg cgattgtccc agttattcac aaacagggag
    27661 ttagcaaaac gcagcgccaa caggttcagc accgtttctt taccaagata gtggtcgata
    27721 cggtaaacct ggcactcctc gaagtattcg ccaacctgat cattgatttc ctgcgaggtc
    27781 gccagcgacg tccccagcgg tttctccatg actacgcgtg ccggtttagc attcagtttt
    27841 gcctcgccaa gccctttgca aattgcgcca aaagtgctgg gcggcatggc aaagtagtta
    27901 atggtgatac gatttttttg atccagcatc gcgccgagaa ggttgaatgc agcagtgtca
    27961 ttgacatcga gattacaaaa atccagacgt gcactcaggg tgtcccataa accttcatca
    28021 atggtttctt tcatgaaagt ttcgagcgcc tcgcggacaa ctttggtata tgccgcttta
    28081 tcccagtcag cacgccctac gccgataatc cgggtgtccg ggttgagctg accggctttt
    28141 tccagttgat acagggaagg cagcaattta cgacgcgcaa ggtcgccttt cgcgccgaaa
    28201 atgaccaggt cacaggcctg ggctgtttgc gttaccgcca tgtcattctc cttaagttaa
    28261 ctaacccggt acttaagcca gggtatactt gtaattttct tacggtgcac tgtactgctt
    28321 ttacgagctt gcgaaaactg taaacgctta tccacccgtg cgattacggg aaaagcgcgc
    28381 aaagtgcggc aaaactgata aaaaaatcat cgttttccat tcggtaaaaa tctgacactg
    28441 atcatgttat gaaaaaaaat aacaactttt ttatctgctt ttgtcattaa cacggcacac
    28501 aggcgtaata tctgacaaaa ctgcatttcg atttctttca gtgcggaaat cgtcattacc
    28561 cgtgagtctc tttacatcat gaatatgctg gaaaaaatcc agtctcagct ggaacatttg
    28621 agcaaatcag agcgcaaagt tgccgaggtc attctggctt cgcccgataa cgcgatccat
    28681 tcgagtattg ctgctatggc actggaagcc aatgttagcg aaccgacggt gaatcgtttc
    28741 tgtcgcagca tggacacgcg cggttttcct gattttaaac ttcatctggc acagagtctg
    28801 gcgaatggca ctccctatgt taatcgcaac gtcaatgaag atgacagcgt tgaatcatac
    28861 acagggaaaa tatttgagtc cgcaatggca acgctcgatc atgtccgtca ttcactggat
    28921 aaatctgcca tcaaccgcgc cgtcgacttg ctcactcagg caaaaaaaat cgcctttttc
    28981 ggattaggct cttcagccgc cgttgcccac gatgcgatga ataagttctt tcgttttaat
    29041 gttccggtgg tgtactccga tgatattgtg ctgcaacgca tgagttgtat gaattgtagc
    29101 gacggagacg tggtggtgct gatttctcac actggaagaa caaaaaatct ggtcgagctg
    29161 gcgcagctgg ctcgcgaaaa cgacgcaatg gtgattgccc tcacctctgc gggtaccccg
    29221 ctcgcccggg aagcaacgct ggcaattacc ctcgacgtac cggaagatac tgacatttat
    29281 atgcccatgg tttctcgact tgcacagctg accgtgatag atgtgctggc gacaggattt
    29341 actttgcgac gcggtgcaaa attcagagat aacttgaagc gggtcaagga agcgctgaag
    29401 gaatcgcgtt ttgataagca gttacttaat ttaagtgacg atcgctaaaa acgactgtca
    29461 ctgtcctaat cttatacgac atccgaatga gattaattta tcgccatcgc ggcgttattt
    29521 cattcggatt tcatgttcaa gcaacacctg gttgtttcag tcaacggagt attacatgtc
    29581 cagaaggctt cgcagaacaa aaatcgttac cacgttaggc ccagcaacag atcgcgataa
    29641 taatcttgaa aaagttatcg cggcgggtgc caacgttgta cgtatgaact tttctcacgg
    29701 ctcgcctgaa gatcacaaaa tgcgcgcgga taaagttcgt gagattgccg caaaactggg
    29761 gcgtcatgtg gctattctgg gtgacctcca ggggcccaaa atccgtgtat ccacctttaa
    29821 agaaggcaaa gttttcctca atattgggga taaattcctg ctcgacgcca acctgggtaa
    29881 aggtgaaggc gacaaagaaa aagtcggtat cgactacaaa ggcctgcctg ctgacgtcgt
    29941 gcctggtgac atcctgctgc tggacgatgg tcgcgtccag ttaaaagtac tggaagttca
    30001 gggcatgaaa gtgttcaccg aagtcaccgt cggtggtccc ctctccaaca ataaaggtat
    30061 caacaaactt ggcggcggtt tgtcggctga agcgctgacc gaaaaagaca aagcagacat
    30121 taagactgcg gcgttgattg gcgtagatta cctggctgtc tccttcccac gctgtggcga
    30181 agatctgaac tatgcccgtc gcctggcacg cgatgcagga tgtgatgcga aaattgttgc
    30241 caaggttgaa cgtgcggaag ccgtttgcag ccaggatgca attgatgaca tcatcctcgc
    30301 ctctgacgtg gtaatggttg cacgtggcga cctcggtgtg gaaattggcg acccggaact
    30361 ggtcggcatt cagaaagcgt tgatccgtcg tgcgcgtcag ctaaaccgag cggtaatcac
    30421 ggcgacccag atgatggagt caatgattac taacccgatg ccgacgcgtg cagaagtcat
    30481 ggacgtagca aacgccgttc tggatggtac tgacgctgtg atgctgtctg cagaaactgc
    30541 cgctgggcag tatccgtcag aaaccgttgc agccatggcg cgcgtttgcc tgggtgcgga
    30601 aaaaatcccg agcatcaacg tttctaaaca ccgtctggac gttcagttcg acaatgtgga
    30661 agaagctatt gccatgtcag caatgtacgc agctaaccac ctgaaaggcg ttacggcgat
    30721 catcaccatg accgaatcgg gtcgtaccgc gctgatgacc tcccgtatca gctctggtct
    30781 gccaattttc gccatgtcgc gccatgaacg tacgctgaac ctgactgctc tctatcgtgg
    30841 cgttacgccg gtgcactttg atagcgctaa tgacggcgta gcagctgcca gcgaagcggt
    30901 taatctgctg cgcgataaag gttacttgat gtctggtgac ctggtgattg tcacccaggg
    30961 cgacgtgatg agtaccgtgg gttctactaa taccacgcgt attttaacgg tagagtaagt
    31021 acgttgccgg atgcggcgaa aacgccacat ccggcctaca gttcaatgat agttcaacag
    31081 atttcgaata ttctgaagca aacttgaact tatcatcagg cgaaggcctc tcctcgcgag
    31141 aggctttttt atttgatggg ataaagatct ttgcgcttat acggctggat ttcgcccggt
    31201 ttgcgagttt tcagcaattt tagtatccag gtgtattgtt ctggtcgcgg accaacaaaa
    31261 atctcgactt cttcattcat ccgccgcgca atcgtatgat catccgcctc taacagatca
    31321 tccatcggtg ggcgcacctg aatcgtcaga cgatgcgtct tgccatcata aatcggaaac
    31381 agcggtacaa cgcgcgcacg gcacactttc atcaaacgac caatcgcggg caacgtcgct
    31441 ttataggtgg caaagaaatc cacaaattcg ctgtgctctg ggccatgatc ctgatcgggt
    31501 aaataatatc cccagtaccc ctgacgtacc gactggatga atggtttaat accgtcattt
    31561 ctcgcatgca gacgaccgcc aaagcgacga cgcaccgtgt tccagacata atcaaaaacc
    31621 gggttgccct gattatggaa catcgctgcc attttctgcc cttgcgaggc catcagcatg
    31681 gcaggaatat cgacggccca accgtgcggc accagaaaga taactttctc gttattacgc
    31741 cgcatctctt cgatgatctc cagcccttgc cagtcaacgc gcggctgaat tttctccggc
    31801 ccgcgtattg ccaactcagc catcattgcc atcgcttgcg gcgcggtggc aaacatctca
    31861 tcaacaatcg cttcgcgttc agcttcacta cgttctggaa agcagagcga cagattgatt
    31921 aacgcacgac ggcgtgagct ttttcccagt cgtccggcaa aacgtcccag ccgtgccaga
    31981 atgggatcac ggaactttgg cggcgttaaa gcgatacccg ccatcgctgc tacgcccagc
    32041 catgctcccc agtagcgcgg gtggcgaaag gatttatcaa actcaggaat gtattcgcta
    32101 ttattttttt tcgtttccat gcttttccag tttcggataa ggcaaaaatc aatctggtga
    32161 tagtgtagcg gcgcaacttg ccccgcacca aataaaaaaa gccggtactg actgcgtacc
    32221 ggctgcgaat ggatgttaat taatcaaacc gtagctgcgg cacaatctct ttggcctgtg
    32281 ccaggaattc gcgacgatcg gagccggtca gcccttcggt acgcggcagt tttgccgtca
    32341 gcgggtttac ggcctgctgg tttatccata cttcatagtg cagatgcggc ccggttgaac
    32401 gtccggtatt accggaaagc gcgatacggt cgccacgttt caccttctgt cccggtttca
    32461 ccagaatctt gcgcaagtgc atataacgcg tggtgtagct gcgaccatga cgaatagcta
    32521 cataataacc tgctgcacca ctgcgtttgg caaccaccac ttcaccgtca cccactgaaa
    32581 gcactggcgt accttgtggc atggcgaaat caacacctct gtgtggtgca acgcgaccgg
    32641 tcaccggatt agtacgacgc gggttaaagt tagacgagat acggaactgt ttcgccgtcg
    32701 ggaatcgcaa gaatcctttc gccagaccag taccgttacg atcgtagaat ttgccatctt
    32761 cagcgcggat agcgtaataa tctttacctt ctgaacgcaa acgtacgccc agcagctggc
    32821 tttgctcacg tttaccatca agcatttctc gagacattaa taccgcaaat tcatcgcctt
    32881 ttttcagttt gcggaaatcc atttgccact gcatggcttt aatcactgcg ctcacttcgg
    32941 cgctggttaa accggcgttt ctggcgctgg caacaaagct ccccccgacg gtacctttca
    33001 gcagattgtt aacccactct ccttgctgca tttcgctggt cattttaaaa ccgttagcgg
    33061 cagtacggtc ataggttcgg gtttcacgac gagacacttc ccaggtgagg cgctgcagtt
    33121 cgccgtccgc ggttaatgtc caggagagtt gttgaccgat tttcaggtta cgcaattctt
    33181 tgtcggccgc agccagttgg gtgatatcac ccatatcaat accatactga ttgagaatgc
    33241 tgcttagcgt atcgccagtg gaaacaacat attcatgcac gcccgcttca ccggcgattt
    33301 tgtcatccag ttcgtcctga ggaatggctt catcttcttg tgcagcttga tcaatcggct
    33361 cactggcttc aggtaagagc gaacgaattt cgttctgttc cagctcaatg gttttgacaa
    33421 ttggcgtggc atcgcggtga taaacatagg gccgccagac agcgacggcc agagtaagaa
    33481 cggtgagcga ccccaacata acgcggtgtg gtcgcggtaa attattaaac gccagggcga
    33541 cagagcgggc tatctgttgc acgtaatcac ttcctcatta atctcctttc aggcagctcg
    33601 catactggtt ggctaattga ctcaggaatt ctgaatagct tgttttaccc agtttgatat
    33661 tcgtccccag gggatccaac gttcccatac gaacggatgt ccctcgtgcg acgctctcaa
    33721 cgaccgctgg cctgaactgt ggctcagcaa aaacgcaggt tgctttttgc tcaaccaact
    33781 gtgttcttat ttcatgtaaa cgctgcgcgc caggttgaat ctcagggtta acggtaaaat
    33841 gaccaagcgg tgtcagtcca aactgttttt cgaaatagcc gtaagcatcg tgaaaaacga
    33901 aataaccttt ccccttgagc ggcgcgagct cgttaccaac ctgcgtttcg gttgaggcta
    33961 attgtgcctc aaaatccttc aggttggcgt caagtttggc tcgactttgc ggcataagtt
    34021 ccactaattt tccatggatt gcaaccgctg tagcccgcgc tatctctggg gaaagccaaa
    34081 gatgcatgtt gaaatcgccg tgatggtgat cttcgtcact tttttccgcg tggtcgtgat
    34141 catcatcatc gccgtgaata cttttcatca gtagcggttt cacatcttca agctgcgcaa
    34201 tcgttacctg cttcgcttct ggtaatttac ttaccggttt ttgcataaac gcttccatct
    34261 ccgggccaac ccaaacgact aagtccgcgt tctgtaagcg ttttacatcc gatggacgca
    34321 gtgaataatc atgttctgaa gcgccgtcag gcagtaaaac ctccgtttct gttaccccat
    34381 cagcaatggc agaagcgatg aacccaacgg gtttaagcga agcgacaact gcggcatctg
    34441 cggcctgtgt tgcaccgccc cagagagcgg cggataatgc tgcgaaaaga agcgtttttt
    34501 tatgtaacat aatgcgacca atcatcgtaa tgaatatgag aagtgtgata ttataacatt
    34561 tcatgactac tgcaagacta aaattaacat gacaagtctg gtttccctgg aaaatgtctc
    34621 ggtttctttt ggccaacgcc gcgtcctctc tgatgtgtcg ctggaactta aacctggaaa
    34681 aattttgact ttacttgggc caaatggcgc aggtaagtcg acactggtac gggtagtgct
    34741 cgggctggta acacccgatg aaggggttat caagcgcaac ggaaaactac gcatcggcta
    34801 tgtaccgcag aagctgtatc tcgacaccac gttgccactg accgtaaacc gttttttacg
    34861 cttacgccct ggcacacata aagaagatat tttgcctgca ctgaaacgtg tccaggccgg
    34921 ccacctgatt aacgcaccga tgcaaaagct ctcgggtggc gaaacgcagc gtgtactgtt
    34981 agcgcgagca ttgttaaatc gcccgcaatt attagtgctg gatgaaccca ctcaaggcgt
    35041 ggatgtaaat ggccaggtgg cgttatatga ccttattgac cagttgcgtc gcgaactgga
    35101 ttgtggcgtt ttaatggttt ctcacgatct gcatctggtg atggcaaaaa ccgatgaagt
    35161 gctgtgcctg aatcaccaca tttgttgttc cggcacaccg gaagttgttt ccctgcatcc
    35221 ggagtttatt tcaatgtttg gtcctcgtgg tgctgaacaa ctgggtatct atcgccatca
    35281 tcataatcat cgtcacgatt tacagggacg aattgttttg cgtcggggaa atgatcgctc
    35341 atgattgaat tattatttcc cggttggtta gccgggatca tgctcgcctg tgccgcgggt
    35401 ccgctgggtt cgtttgtagt ctggcgtcgt atgtcttatt tcggtgatac gctggctcat
    35461 gcctcattac ttggcgtcgc gtttggtttg ttgctggacg tgaatccatt ctatgcggtg
    35521 attgccgtta cgctgctgct ggcgggcggt ctggtatggc tggagaagcg tccacagctg
    35581 gcgatcgaca cgttattagg gattatggcg cacagtgccc tgtcgctggg cctggtggtc
    35641 gttagtctga tgtctaatat tcgtgttgat ttgatggctt acttgttcgg tgatttgctg
    35701 gcagtgacgc cggaagatct catctccatc gccattggcg tggtcatcgt ggtggctatt
    35761 ttgttctggc aatggcgcaa tttgctgtcg atgacgatta gcccggatct ggcgtttgtt
    35821 gatggtgtga aattacagcg cgtgaaattg ttattgatgc tggtgacggc attgacgatt
    35881 ggtgtagcga tgaaatttgt cggtgcgttg attattactt cgttgctgat tattcctgca
    35941 gctactgcgc gtcgctttgc ccgcacgccg gaacagatgg ctggtgtcgc tgttttggtg
    36001 gggatggtgg cagtgactgg cggtttaacc ttttccgcat tttacgatac gccggcgggt
    36061 ccgtcggtag tgctatgtgc ggcactgtta tttattctca gtatgatgaa aaagcaggcc
    36121 agttaatctg tcgctgaaca catttgtcgg atgcggcgcg agcgccttat ccgacctacg
    36181 gttcggtatc tctggtagtc ctggtaagac gcgaacagcg tcgcatcagg catattgcca
    36241 gtgccggatg cggcgcgagc gaccaatccg acttacggca tttctggcgg cgttatgcca
    36301 aagtgattcc acgcccgcgt cgtcgccata cgcccacgcg gtgtacgctg caaaaagcct
    36361 tgctgaatca aataaggttc cagcacatcc tcaatggttt cacgttcttc gccaatggct
    36421 gccgccaggt tatccagacc tacaggtcca ccaaagaact tatcgattac cgccagcaac
    36481 aatttgcggt ccatataatc gaaaccttca gcatcgacat tcaacatatc cagcgcctga
    36541 gcagcgatat ctgccgagat ggtgccatcg tgcttcactt cggcgaaatc acgcactcga
    36601 cgcagcagac ggttggcaat gcgcggcgta ccgcgagcgc gacgagcaac ttccagcgcg
    36661 ccgtcatcac tcatctcaag ccccataaag cgtgcgctgc gactgacgat atattgcaga
    36721 tccggcacct gataaaactc cagacgttgc acaataccaa aacggtcgcg caacggtgat
    36781 gtcagcgaac ctgcgcgcgt ggttgcacca atcagggtaa acggcggcaa atcaatttta
    36841 atggagcgtg ccgccggacc ttcaccaatc atgatatcca gttggtagtc ttccattgcc
    36901 gggtacagca cttcttcaac aactggcgat agacggtgga tctcatcaat aaacagcacg
    36961 tcatgcggtt caaggttagt gagcatcgca gccaaatcgc ccgccttttc cagcaccgga
    37021 ccagaagtcg tgcgtaaatt aacgcccatt tcattggcga caatgttggc aagcgtagtt
    37081 ttacccaacc ccggaggacc aaaaatcaac aaatgatcga gggcatcgcc gcgcagtttc
    37141 gctgctttga tgaaaatctc catctgtgaa cgaacctgcg gctgaccaac atactcttcc
    37201 agtaatttgg ggcgaatggc gcgatctgct acatcttccg gcaaagtggt accggcagaa
    37261 atcagacggt ctgcttcaat catcctttac ctcataacgc ggcgcgtagg gcttcgcgaa
    37321 ttaaagtttc actgctggcg tcagggcgag cgattttgct caccatgcgg cttgcttctt
    37381 gtggtttata gcccagcgcc accagcgcgg caaccgcttc ttgttcagca tcgtcggtcg
    37441 ccgggctggc aggagacgtg agtaccaggt cggcggctgg cgtaaagaga tcgccatgca
    37501 aacctttaaa tcggtctttc atttcaacaa tcaagcgttc ggcggttttt ttgccaatac
    37561 ccggcagttt caccagtgcc cccacttctt cacgctcaac ggcattaacg aactgctgcg
    37621 ctgacattcc ggagaggatc gccagcgcca acttcgggcc gacgccgttg gttttgatca
    37681 actctttgaa caatgtgcgc tcttgtttat tgttaaaacc gtacagcagt tgcgcgtctt
    37741 cacgcaccac aaagtgggtg aaaacgatcg cttcctgacc cgcttcaggg agttcataaa
    37801 aacaggtcat cggcatatgc acttcatagc ctacgccgcc cacttcaatt aacaccagcg
    37861 ggggttgttt ttcaatgatg atgcctctga gtctgcctat cacatgacgc tcctgcgtaa
    37921 tgaatcaaag ataatgctgt atgataaaaa aatgctggat agatatccag cgaaggatga
    37981 agaaaacttg cgaggtgtct cgatgaactg aa
//
LOCUS       DAPHKZ010000036        37678 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.036, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000036 DAPHKZ010000000
VERSION     DAPHKZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37678
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.036"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(474..1250)
                     /gene="sseB"
                     /locus_tag="RH288_001896"
     CDS             complement(474..1250)
                     /gene="sseB"
                     /locus_tag="RH288_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708361.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HDV4030951.1"
                     /translation="MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGE
                     AVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVEDEQAFVVMPVRTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLIGEEGNPLSSQEILEGGESLILSEVAEPPAQMIDSLTT
                     LFKTIKPVKRAFICSIKENEEAQPNLLIGIEADGDIEEIIQATGSVATDTLPGDEPID
                     ICQVKKGEKGISHFITEHIAPFYERRWGGFLRDFKQNRII"
     gene            complement(1392..2675)
                     /gene="pepB"
                     /locus_tag="RH288_001897"
     CDS             complement(1392..2675)
                     /gene="pepB"
                     /locus_tag="RH288_001897"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417018.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HDV4030952.1"
                     /translation="MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLI
                     QRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVVWPDLDDAQRQELDN
                     RLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGL
                     HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNT
                     DAEGRLVLADGLIDASAQKPEMIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLAS
                     AAQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGW
                     LHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA"
     gene            complement(2853..3053)
                     /gene="iscX"
                     /locus_tag="RH288_001898"
     CDS             complement(2853..3053)
                     /gene="iscX"
                     /locus_tag="RH288_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HDV4030953.1"
                     /translation="MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICDLEDFDD
                     DPQASNEKILEAILLVWLDEAE"
     gene            complement(3065..3400)
                     /gene="fdx"
                     /locus_tag="RH288_001899"
     CDS             complement(3065..3400)
                     /gene="fdx"
                     /locus_tag="RH288_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HDV4030954.1"
                     /translation="MPKIVILPHQDLCPDGAVLEANSGETILDAALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIPR
                     YTINHAREH"
     gene            complement(3402..5252)
                     /gene="hscA"
                     /locus_tag="RH288_001900"
     CDS             complement(3402..5252)
                     /gene="hscA"
                     /locus_tag="RH288_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HDV4030955.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     ADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPH
                     LPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKI
                     ALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVM
                     VGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSE
                     IASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAA
                     AHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV"
     gene            complement(5269..5784)
                     /gene="hscB"
                     /locus_tag="RH288_001901"
     CDS             complement(5269..5784)
                     /gene="hscB"
                     /locus_tag="RH288_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HDV4030956.1"
                     /translation="MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQ
                     LAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREEL
                     DEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            complement(5880..6203)
                     /gene="iscA"
                     /locus_tag="RH288_001902"
     CDS             complement(5880..6203)
                     /gene="iscA"
                     /locus_tag="RH288_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HDV4030957.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCG
                     ESFHV"
     gene            complement(6220..6606)
                     /gene="iscU"
                     /locus_tag="RH288_001903"
     CDS             complement(6220..6606)
                     /gene="iscU"
                     /locus_tag="RH288_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HDV4030958.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            complement(6634..7848)
                     /gene="iscS"
                     /locus_tag="RH288_001904"
     CDS             complement(6634..7848)
                     /gene="iscS"
                     /locus_tag="RH288_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDV4030959.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
                     QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR
                     LWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLE
                     PSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            complement(7960..8448)
                     /gene="iscR"
                     /locus_tag="RH288_001905"
     CDS             complement(7960..8448)
                     /gene="iscR"
                     /locus_tag="RH288_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HDV4030960.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKL
                     RA"
     gene            complement(8809..9549)
                     /gene="trmJ"
                     /locus_tag="RH288_001906"
     CDS             complement(8809..9549)
                     /gene="trmJ"
                     /locus_tag="RH288_001906"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HDV4030961.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGNKAE"
     gene            9668..10471
                     /gene="suhB"
                     /locus_tag="RH288_001907"
     CDS             9668..10471
                     /gene="suhB"
                     /locus_tag="RH288_001907"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HDV4030962.1"
                     /translation="MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVS
                     IAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            10616..11470
                     /locus_tag="RH288_001908"
     CDS             10616..11470
                     /locus_tag="RH288_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417029.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV4030963.1"
                     /translation="MALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGP
                     DPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLP
                     ERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
                     NILDVIGRGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIP
                     LLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFI
                     LSALNPQN"
     gene            11661..12941
                     /gene="csiE"
                     /locus_tag="RH288_001909"
     CDS             11661..12941
                     /gene="csiE"
                     /locus_tag="RH288_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HDV4030964.1"
                     /translation="MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATMATFSELNGVDD
                     DIASLDISETGREILRYHQLTLTTGYDGSYRVEGTVLNQRLCLFHWLRRGFRLCPSFI
                     TSQFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFESRDIHFLCLYLQYCL
                     LQHHAGITPQFNPLQRRWAESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSML
                     RVPDPLRDAHQRDRQLRQSIKRLVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLF
                     AIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESGLVAVIFGAWLMQEN
                     DLHEKQIILLTGNDSEREAQIEQQLRELTLLPLNIKHMSVKAFLQTGAPRGAALIIAP
                     YTMPLPLFSPPLIYTDLTLTTHQQEQIRKMLESA"
     gene            complement(12933..14072)
                     /locus_tag="RH288_001910"
     CDS             complement(12933..14072)
                     /locus_tag="RH288_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HDV4030965.1"
                     /translation="MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLL
                     LGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIG
                     FNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVTMFDYRVIL
                     ALLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAH
                     AAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAIC
                     GVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC"
     gene            complement(14232..15122)
                     /gene="hcaR"
                     /locus_tag="RH288_001911"
     CDS             complement(14232..15122)
                     /gene="hcaR"
                     /locus_tag="RH288_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HcaR"
                     /protein_id="HDV4030966.1"
                     /translation="MELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVG
                     VPLLVRDKRKVALTAAGECFLQDALAILEQAENAKLRARKIVQEDRQLTIGFVPSAEV
                     NLLPKVLPMFRLRQPDTLIELVSLITTQQEEKIRRGELDVGLMRHPVYSPEIDYLELF
                     DEPLVVVLPVDHPLAHEKEITAAQLDGVNFVSTDPVYSGSLAPIVKAWFAQENSQPNI
                     VQVATNILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEM
                     KPALRDFIAIVQERLASVTA"
     gene            15258..16619
                     /locus_tag="RH288_001912"
     CDS             15258..16619
                     /locus_tag="RH288_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="HDV4030967.1"
                     /translation="MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWL
                     FLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRA
                     FTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSA
                     PGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSH
                     ASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWV
                     DGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRGPDQVE
                     VWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKL
                     CLEMGLGQEKRRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQE
                     VMK"
     gene            16616..17134
                     /locus_tag="RH288_001913"
     CDS             16616..17134
                     /locus_tag="RH288_001913"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate/cinnamic acid dioxygenase
                     subunit beta"
                     /protein_id="HDV4030968.1"
                     /translation="MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTM
                     RTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNC
                     QISETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQ
                     AVITSHNLSVLF"
     gene            17134..17454
                     /locus_tag="RH288_001914"
     CDS             17134..17454
                     /locus_tag="RH288_001914"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-phenylpropionate/cinnamic acid
                     dioxygenase ferredoxin subunit"
                     /protein_id="HDV4030969.1"
                     /translation="MNRIYACPVADVPEGEALRIDTSPVIALFNVGGEFYAINDRCSH
                     GNASMSEGYLEDDATVECPLHAASFCLKTGKALCLPATDPLTTYPVHVEGGDIFIDLP
                     EAQP"
     gene            17451..18263
                     /gene="hcaB"
                     /locus_tag="RH288_001915"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
     CDS             17451..18263
                     /gene="hcaB"
                     /locus_tag="RH288_001915"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
                     /EC_number="1.3.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate-dihydrodiol/cinnamic
                     acid-dihydrodiol dehydrogenase"
                     /protein_id="HDV4030970.1"
                     /translation="MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVA
                     SLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPA
                     ETLETGFHELFNVNVLGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASK
                     HAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAIL
                     PLQFFPQPADFTGPYVMLTSRRNNRALSGVMINADAGLAIRGIRHVAAGLDL"
     gene            18273..19475
                     /locus_tag="RH288_001916"
     CDS             18273..19475
                     /locus_tag="RH288_001916"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylpropionate dioxygenase ferredoxin
                     reductase subunit"
                     /protein_id="HDV4030971.1"
                     /translation="MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYER
                     PPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWD
                     QLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIIGAGTIGLELA
                     ASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKV
                     ELTLQSGETLQADVVIYGIGISANEQLAREANLDTANGIVIDEACRTCDPAIFAGGDV
                     AITRLDNGALHRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSDQYSDNLQFIGDM
                     RGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQSGKTFDAKLLID
                     ENIALKSL"
     gene            19572..19994
                     /locus_tag="RH288_001917"
     CDS             19572..19994
                     /locus_tag="RH288_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417038.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDV4030972.1"
                     /translation="MNTLRYFDFGAARPVLLLIARIAVVLIFIIFGFPKMMGFDGTVQ
                     YMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRPLAVLFIFYTLGTAVIGHHYWDM
                     TGDAVGPNMINFWKNVSIAGAFLLLAITGPGAISLDRR"
     gene            complement(20042..20914)
                     /locus_tag="RH288_001918"
     CDS             complement(20042..20914)
                     /locus_tag="RH288_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HDV4030973.1"
                     /translation="MTIYTLSHGSLKLDVSDQGGVIEGFWRDTTPLLRPGKKSGVATD
                     ASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGEWQCVSHSDDSLC
                     LVYEHRSGVYHYRVSQAFHLTADTLTVTLSVTNQGAETLPFGTGWHPYFPLSPQTRIQ
                     AQASGYWLEREQWLAGEFCEQLPQELDFNQPAPLPRQWVNNGFAGWNGQARIEQPQEG
                     YAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPG
                     ESTTSEMSLRVEWL"
     gene            complement(20926..22020)
                     /locus_tag="RH288_001919"
     CDS             complement(20926..22020)
                     /locus_tag="RH288_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDV4030974.1"
                     /translation="MKINRIVNEGFMKTMLAAYLPGNSTVDLREVAVPTPGINQVLIK
                     MKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDR
                     VLVYHISGCGFCPNCRRGFPISCTGEGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
                     YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM
                     LPERLAMAKQLGVMDHGYLATTEGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTA
                     DWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAI
                     THRFSLEQAGDAYALMASGKCGKVVINFPD"
     gene            complement(22053..23051)
                     /locus_tag="RH288_001920"
     CDS             complement(22053..23051)
                     /locus_tag="RH288_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4030975.1"
                     /translation="MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNA
                     PGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEV
                     PLAVACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPID
                     ENEVLDWLGGQFLGVPVSALIMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGIN
                     VRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRG
                     SLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANILLTQRSSKAKR"
     gene            complement(23076..24587)
                     /locus_tag="RH288_001921"
     CDS             complement(23076..24587)
                     /locus_tag="RH288_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDV4030976.1"
                     /translation="MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGK
                     NGAGKSTLIRMLTGSERPDSGEIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEG
                     LTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEI
                     ARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASC
                     ATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIVDQAVLEVRALRHKP
                     KLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLEEYEQGEIVINGEKITRPDYGDM
                     LKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMT
                     VKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVREL
                     AAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHAPVNVDELMSAILSVH"
     gene            complement(24610..25593)
                     /locus_tag="RH288_001922"
     CDS             complement(24610..25593)
                     /locus_tag="RH288_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDV4030977.1"
                     /translation="MPKKMRTTRNLLLMATLLGSALFARAADKEMTIGAIYLDTQGYY
                     AGVRQGVQDAAKDSSVQVQLIETNALGDISKESTFVDPLVARNVDAIILSAVSENGSS
                     RTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKID
                     QPKIAVINCEAFEVCVQRRKGFEEVLKSRVPGAQIVANQEGTVLDKAISVGEKLIIST
                     PDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDIS
                     GKKMGNAVFAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP"
     gene            complement(25690..28971)
                     /locus_tag="RH288_001923"
     CDS             complement(25690..28971)
                     /locus_tag="RH288_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HDV4030978.1"
                     /translation="MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYG
                     VTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPA
                     LVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHEDGAQTVWVGETEPMHGLQVMT
                     GFTLRPDRAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKR
                     AVSAFPIATGTYYKVDYSAGVDISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLH
                     VANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEE
                     KRFEQYFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLNGYRLAIREIGKCN
                     ALLDDAVALMPATAIQGVLHGINPERLTIELSDADGNIVLSYQEHQPQELPLPDVAKA
                     PLAAQDITSTDEAWFIGQHLEQYHHASRSPFDYYLRGVALDPLDYRCNLALAMLEYNR
                     ADFPQAVAYATQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWRAVWSGN
                     SKAGGYYGLARLAARNGNFDAGLDFCQQSLRACPTNQEVLCLHNLLLVLSGRQDNARV
                     QREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPTL
                     AAEMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDVFPQFVRFPNTLEEVAALESI
                     EECWFARHLLACFYYNKRSYNKAIAFWQRCVEMSPEFADGWRGLAIHAWNKQHDDELA
                     ARYLDNAYQLAPQDARLLFERDLLDKLSGATPEKRLARLENNLEIALKRDDMTAELLN
                     LWHLTGQADKAADILATRKFHPWEGGEGKVTSQFILNQLLRAWQHLDAREPQQASELL
                     HAALHYPENLSEGRLPGQTDNDIWFWQAICANAQGDETEAMRCLRLAATGDRTINIHS
                     YYNDQPVDYLFWQGMALRLLGEQQTAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLL
                     SLYGDLQQQHKEKCLMVAMLASAGLGEVAQYESARAELTAINPAWPKAALFTTVMPFI
                     FNYVH"
     gene            29089..30282
                     /locus_tag="RH288_001924"
     CDS             29089..30282
                     /locus_tag="RH288_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDV4030979.1"
                     /translation="MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAV
                     SNILQELESEKRVVNIDDKSQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACL
                     SPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
                     MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIG
                     SSFVINEQIYRGSLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLK
                     SQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSLYNFLNILNINQIWL
                     YGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEA
                     QLRQI"
     gene            complement(30480..31733)
                     /gene="glyA"
                     /locus_tag="RH288_001925"
     CDS             complement(30480..31733)
                     /gene="glyA"
                     /locus_tag="RH288_001925"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDV4030980.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
                     QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVAL
                     KEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDS
                     INDEAVIERIKGKVLDICARYPVYA"
     gene            32061..33251
                     /gene="hmpA"
                     /locus_tag="RH288_001926"
     CDS             32061..33251
                     /gene="hmpA"
                     /locus_tag="RH288_001926"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HDV4030981.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHL
                     LATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
                     TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYR
                     IAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLA
                     MLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTAHTWYRQPSEADRAK
                     GQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQFTAKQLVDLGVKQENIHYECFGP
                     HKVL"
     gene            complement(33296..33634)
                     /gene="glnB"
                     /locus_tag="RH288_001927"
     CDS             complement(33296..33634)
                     /gene="glnB"
                     /locus_tag="RH288_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HDV4030982.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDICVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(33695..35029)
                     /gene="glrR"
                     /locus_tag="RH288_001928"
     CDS             complement(33695..35029)
                     /gene="glrR"
                     /locus_tag="RH288_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HDV4030983.1"
                     /translation="MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRV
                     LNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFS
                     FLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
                     LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVS
                     NREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDINVRIISAT
                     HRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVR
                     AFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFV
                     EARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE"
     gene            complement(35019..35732)
                     /gene="qseG"
                     /locus_tag="RH288_001929"
     CDS             complement(35019..35732)
                     /gene="qseG"
                     /locus_tag="RH288_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HDV4030984.1"
                     /translation="MRHIFQRLLPRRLWLAGLPCLALLGCVQNHNKPAIDTPAEEKIP
                     VYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGSWQ
                     NTFKQGILLADAKITPYERRQLVARIEALSTEIPAQVRPLYQLWRDGQALQLQLAEER
                     QRYSKLQQSSDSELDTLRQQHHVLQQQLELTTRKLENLTDIERQLSTRKPAGNFSPDT
                     PHESEKPAPSTHEVTPDEP"
     gene            complement(35897..37324)
                     /gene="qseE"
                     /locus_tag="RH288_001930"
     CDS             complement(35897..37324)
                     /gene="qseE"
                     /locus_tag="RH288_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HDV4030985.1"
                     /translation="MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     ALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHA
                     GVLPDDKLYQALRQDLHNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
                     GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLG
                     NSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETV
                     VSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSS
                     HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     ELYLVDESGQDVCFRIELPSSKNTK"
BASE COUNT         8849 a        10381 c         9539 g         8909 t
ORIGIN      
        1 aaaccgccaa aatcaggcgg ttttttgttg ctggtccggt tcgcggcctt tccagcaggt
       61 tgtattaccg tagtaatgca agcgcgtctc agcggagaca atactcgcca gtaactctct
      121 ttttgtcaag caaaagagag ttattattgt tctgttagtg tattatccac tgcggccctt
      181 tccgccgtct cgcaaacggg cgctggcttt aggaaaggat gttccgtggc cgtaaatgca
      241 ggtgtttcac agcgcttgct atcgcggcaa tatcgccagt ggtgctgtcg tgatgcggtc
      301 ttcgcatgga ccgcacaatg aagatacggt gcttttgtat cgtacttatt gtttctggtg
      361 cgctgttaac cgaggtaaat aataaccgga gtctctccgg cgacaattta ctggtggtta
      421 acaaccttca gagcagcaag taagcccgaa tgccgccctt tgggcggcat attttagatt
      481 atccgattct gtttaaagtc acgcaaaaaa ccaccccagc gacgttcata gaatggcgca
      541 atatgttcgg taataaagtg gctaattcct ttttcccctt ttttcacctg acaaatatcg
      601 attggttcat cgccaggtaa tgtatcggtc gctacacttc ccgtcgcctg aataatttct
      661 tcgatatcac catcggcttc aatgccaata agtaaattag gctgtgcctc ttcgttctct
      721 ttaattgaac aaataaaagc acgcttcacc ggcttaatgg ttttaaataa ggtggtgagt
      781 gaatcaatca tttgtgctgg cggctctgcg acttccgata atatcagcga ttcaccgcct
      841 tccaggattt cctggctgct cagcggattt ccctcttcac caatcaacaa actgatttca
      901 cgcggcataa attctttacc ggttggcagt ttggcattaa ggaagagcgt ttcgccaagt
      961 gtcatctcaa acagcgtgcg aacgggcatt acgacaaatg cctgttcgtc ttcaaccgcc
     1021 tgttgaagtg cttctaacga ggtgaaaaaa ggaatgacgc tggtgccgtc ttctttttcc
     1081 cagtgctgta aatcaagcgc gctatcttca accacagcct cgccctgcgc cgccgtacca
     1141 ggcacccaga cggtggattc cagtagagta cggaaaaagg ccgggcggtg cgccggttca
     1201 gttgctgctt tttccagcag gtcttcaagt tcgttttttg tttcggacat aagaaccaca
     1261 attcattcaa cgttcggggc gcaaatgcct gatgcgctac gcttatcagg cctacaaggg
     1321 attcgcaatt tgttgaattt gcagaatttg taggccggat aaggcgttta cgccgcatcc
     1381 ggcatattag tttacgccgt taacagatta gctatcgtgc gcacaccaag tcccgtagcg
     1441 cccgcagacc actgttcaac cggcgcttta cggtaggtcg ccgagcagtc gatatgcagc
     1501 cagccttgct gatagttctc aacaaagtgc gacaggaagc ccgccgccgt gctcgcgcct
     1561 gccggatacg ccgcgcttcc ggtattgttc agttcggcaa agttagacgg cagctggctg
     1621 cggtggaact ccgccagcgg cagacgccag aacggttcgt tctcctgcgc ggcactcgcc
     1681 agcaagcgac cggccagcgc atcgtcaaaa ctgaacagcg cgtgataatc attacccagc
     1741 gcagttttcg ccgccccggt gagggtcgcc gcatcaatga tcatttccgg tttctgcgca
     1801 ctggcatcaa tcagaccatc ggcaagcacc agacgccctt cggcatcagt gttcatcact
     1861 tcaacttttt taccgttgcg ataggtgatg atatcgccca gcttgaacgc attgccgcta
     1921 atcaggttat ccgcacagca gaggaacagc ttcacgcgct tgttcagtcc gcgcgtaatg
     1981 gcaaatgcca gcgccccggt aaccgttgcc gcgccgccca tgtccgactt catcgagtcc
     2041 ataaacgcag tctgtttgat gctgtagccg ccggagtcaa aagtgatacc tttacctacc
     2101 aggcacgcgt acactggcgc ttctttatcg ccagttgggt tgtaatccag cgccagcaat
     2161 accggagaac gttctgaacc gcgtccgact gtgtgcagcc ccatataacc ttgctcacgc
     2221 agatcttcgc ctttggtgat ccgataagtc acacgatcgc ccgcgacgtt gctgatcaga
     2281 tcaacagcac gctgtgccag ttgcgatggt cccaattctt ctgccggtgc gttgatggtg
     2341 tcacgcaccc agtcgatgat catcaggcgg ttatccagtt cctggcgctg ggcatcgtcc
     2401 agatccggcc acaccacttt acgcgtgcct ttcggggctt tgtaaccttg ccagaatgcc
     2461 cagcagcgat ccgcatccca gccttcaccg cttaactgaa catgcttgat gcccagaccg
     2521 tcaatcttgc gcgccgcacg ctggatcagc cccagatcgt ctgccccgtt caaatgcagg
     2581 gtaatgccgt cattattaat gctgtaagtt gctttttctc cccagcgcgc gtcggcaggt
     2641 tgggtagaga gggtaatctt catcgcttct gtcattttag ttatccttct ttgtaaaagg
     2701 gccgccagtt ggcagcccca ggatttttcc gctaaatgat tcgcgttgca ggaaggcggc
     2761 aagtgagtga agccccagga gcatagataa ctatgtgact ggggtgaacg agcgcagcca
     2821 acgcatctgc ggcgtgaagc atgacgcgga aattattcgg cctcgtccag ccagactaac
     2881 aaaatcgctt cgaggatttt ctcgttggat gcctgcgggt cgtcgtcgaa atcttccaga
     2941 tcgcaaatcc actgatgcat atcggtgaat cgaaccgttt tcggatcaag atcgggatac
     3001 gcatcgtaca gtgcttcgcc aatttcgcgg ctatcggtcc acttaagtcc catactaacc
     3061 tctgttaatg ctcacgcgca tggttgatag tgtaacgcgg gatttcgact actaaatctt
     3121 cgtcggtaac gcgcgcctgg cagcttaaac ggctttccgg ctccagtccc caggctttgt
     3181 ccagcatgtc gtcttcctgc tctgagcttt ccggcagtga gtcaaaacct tcacgaacga
     3241 tgcagtggca ggtggtgcaa gcacaggatt tttcacaggc gtgttcaatc tcgataccgt
     3301 tacgcagagc tgcgtcgaga atggtttcac cgctattagc ttccagaaca gcgccatcag
     3361 ggcagagatc ctgatgaggc aaaataacaa tctttggcat attaaacctc gtccacggaa
     3421 tggcctttca gcgcacgacg aaccgactgg tccatgcggc gagcggcgaa atcctgggtt
     3481 tgtttgtcta cgtttttaat cgcttgttcg atggcgtcaa catcatcgcc ctgcgccact
     3541 tcactcaggt gagcggcagc atcgtcaatg acctgacgtt ctgcggcgct taacagcgcg
     3601 gcatcagcag ccagcgcgcc gtgcagactt tccagcacac gcgccgcttc tactttttgt
     3661 tctgccagca ttcgggcttt tacgtcctgc tcggcatagc tcattgagtc tttgatcatc
     3721 gaagcgattt cgctatcggt cagaccgtaa gacggtttga cctgaataga cgcctcaacg
     3781 ccggtggatt tctccatcgc cgtcacgctc aaaagaccgt cggcatcgac ctggaacgtc
     3841 acgcgaatat gcgcaccgcc agccggtagc gccggaatac cacgcagcgc aaaacgcgcc
     3901 agtgagcggc agtcctgcac cagttcgcgc tcaccctgca ttacatggat agacatcgcc
     3961 gtctgaccat ctttaaaggt ggtgaaatcc tgagcgcggg ccaccggaat agtggtatta
     4021 cgcggaatca ctttctccac caggccgccc atcgtttcga ggcccagcga cagtgggatc
     4081 acatcaagca acagcatttc gctgtctggc ttgttaccca ccagaatatc cgcctgaatc
     4141 gccgcgccaa tagcgacgac tttatccggg tcgatggaag tcagcggtgg acgaccgaaa
     4201 aattcgccta cccgttcacg caccagcggc acgcgagtag aaccgcccac catcaccact
     4261 tccagcactt catcagcttc tacacccgcg tctttcagcg cgcgacgaca agccagtaag
     4321 gttcgtttta ccagtggcgc gatcagttca ttgaattgtt cacggctgat ttcgccctgc
     4381 cagcccgcaa cgttaacggt cacggagtcc gcatcgctca gcgcgatttt ggctgcaatg
     4441 gcggcatcca gcagttcacg ctgaacgcgg ttatcgctac gatcaggaat gcccgcctgc
     4501 tcgcgaatgt aatccgccag cagatggtcg aaatcatcgc cgccgagcgc ggaatcaccg
     4561 ccggttgcca gcacttcaaa cacgccgcga cttaagcgca gaatggaaat atcaaacgtc
     4621 ccgccaccga ggtcataaac ggcgatcacg ccttcctgac cggaatccag cccgtaggcg
     4681 atagccgcag cggtcggttc gttaagtaag cgcaggacgt gaaggcccgc cagacgcgcc
     4741 gcgtctttgg tgccctgacg ctgggcatcg tcaaagtacg ccggaacggt gataactaca
     4801 ccatccagct cgcctgccag ggcttcagtt gcccgcgccg ccagtgcttt gaggatgtcc
     4861 gcagaaacgc gcaccgggtt cagcagcccc gccgccgttt caatcatcgg caggccgttt
     4921 tcgctggcct ggaattgata aggcagatgc ggatagcgtt gctggatatc agccagcgag
     4981 cgtcccatca ggcgtttaac agaactaatt gtgttggcgg tatcgagcgc tgcattagta
     5041 cgcgcgtcat aacccaccga atgcccttgc tgttgatagt gaacaacaga tggcagcagg
     5101 tgacggcctt catgatcggc taacgtttcg gcctgaccgc tgcgcactgt cgccaccagc
     5161 gagttggttg tgcccaggtc aataccggcc gccagacgac gctgatgcgg cgcagcactc
     5221 aaaccaggtt cactaatttg taataaggcc atgtttagct tccagaaatt aaaaatcgag
     5281 cagtttttct tcgagttgtt cggcactgct tcgcagttta tcgagaaaac gcagcttacg
     5341 cacggtatcc gccgccgcgt cccacgtctc gttgtctaac tgttcaacca tcaactgatg
     5401 gcgggtatca aacatctttt tcacacgttt gataaagctt tccagccgcg cttcatcttt
     5461 cgcctgttcg atctcgtcca gctcttcgcg cagctccaac tgttccatca ggaacgcggt
     5521 gtcgcgcaca gtatgctgct cgctggcgag atcaaagccg tgcaaagaaa gcaaatattc
     5581 cgcgcgcatt aacggatgac gcagcgtttg ccaggcctgg ttaatggttg cagattgctg
     5641 tacggcggcg agttgttccg cctggcttcc gctggcgaat ttatcaggat gatactgacg
     5701 ttgtagatcc tgaaaacgca ggctcagcgc ctgggtatcg agttgatagc gggcaggcaa
     5761 gccaaagagg gtgaagtaat ccataacatt ctcagggctg cgatccgccg cgataacggc
     5821 gaatcaggta aaacaaaccc cacgcgcagg cgaccacggt ggggttatcg gtatgcgcat
     5881 caaacgtgga agctttcgcc gcaaccacac tcatctttga cgttcgggtt ggtgaattta
     5941 aacccttcgt tcaggccttc ttttacgaag tccagctgcg taccgtccag aaattgcagg
     6001 ctcttgccat cgaccacgac tttcacgcct ttgtcttcaa acacgatgtc ttccggcgtc
     6061 ggttcgtcaa caaattccag tacataagcc atacctgaac acccggaggt tctcacgccc
     6121 agacgcaggc caaacccttt accgcggtta gccagaaagg tatttactcg cgctgctgca
     6181 ctgtcgctca gtgtaatcga cataaccaaa cctcaactct tattttgctt cacgtttgct
     6241 tttatagtcc gcaatggcgg ctttgatcgc gtcttctgcc agaatagaac agtgaatttt
     6301 caccggcggc agttcaagtt cttcagcaat atcggtgttt ttgatcgcct gcgcttcgtc
     6361 gagagacttc cctttcaccc attcggtgac cagggagctg gaagcgatag cggaaccgca
     6421 gccgtaagtt ttaaaacgcg cgtcttcaat gataccttca tcgttgactt taatctgcaa
     6481 cttcatcacg tcgccacagg ccggtgcccc caccatgccg ctgccgacgt tctcgtcgtt
     6541 gttgtcaaag gaacccacgt tacgcggatt ctcgtaatgg tcgataactt tttcgctgta
     6601 agccattata aattctcctg attccgatac cgattaatga tgagcccatt cgatgctgtt
     6661 cagatccacg ccctgcttgt acatttccca cagcggagaa aggtcacgca gacgaccgat
     6721 ggatttacga actaactcga tggtgtagtc gatctcttct tcagtagtaa aacgacctaa
     6781 agagaaacgg atagagctat gtgccagctc gtcgttcagc cccagcgcgc gcagcacgta
     6841 ggacggttcg aggcttgctg acgtacaggc ggaacctgaa gaaactgcga ggtctttcag
     6901 cgccataatc agcgactcac cttcaacgta gttgaagctg acgttgagaa tgttcggcgc
     6961 accgtgttcc aggtcaccgt tcaggtaaac ttcttcgata tctttgatgc cgttccacag
     7021 acggttacgc aggccgcgca gacgttccat ctcggtcgcc atctcttctt ttgcgatgcg
     7081 ataggcctcg cccattccga cgatctggtg aacaggcaga gtgccggaac gcataccgcg
     7141 ctcgtgaccg ccgccgtgca tttgcgcttc gatgcgtacg cgcggtttac gacgtacata
     7201 cagcgcaccg atacctttcg ggccatagat tttgtgaccg gagaaagaca tcaggtcaac
     7261 tttcaactgg ctcaggtcga taggcagttt acccacgctc tgggttgcat caacgtgata
     7321 gataatgcca cgagcacggc acatttcgcc gatagccgcg atatcctgca ccacgccgat
     7381 ttcgttattt acgtgcatga tggacacgag gatggtgtcg tcacgcatcg ctgcttcaag
     7441 ttctttcagg tcgataatgc cgttacgctg cggtgccagg taggtgactt caaaaccttc
     7501 gcgctccagc tgacggcagg tatccagtac cgctttgtgt tcggttttgc tggtgatgat
     7561 gtgcttgcct tttttctgat aaaagttggc tgcacctttg atcgccaggt tgtcagattc
     7621 ggttgcacca gaggtaaaga cgatttcacg cggatcagcg ccgaccagat cggcaatctg
     7681 attacgggcg atatctaccg cttcttcagc ctgccagccg aaacggtgag aacgggaggc
     7741 cgggttacca aaggttccgt ccatcgtcat aaactgcatc attttctcgg caacacgcgg
     7801 gtccaccggc gtggttgcgg agtagtcgag ataaatcggt aatttcattg ctctataaac
     7861 tccgtacatc actcaatgca aggaatcagg ctaccggctg gatgtacgac cgtgtttacg
     7921 gagtatttag cactccggcc tgattctgaa ttctttttat taagcgcgta acttaacgtc
     7981 gatcgcgtct tgtgtgcggg tgcgtggcgc gtcgtgagta tgctgacgac cagacacatc
     8041 cagcacttcc tggttattaa ccagttcgcc taaagtaatg ttgttgagaa aaccggtgag
     8101 acggtcgctc aaatcacgcc acagcgcgtg ggtcaggcat ttatcgccgc cctggcagcc
     8161 gcctttaccc tgacaacggg tggcatctac agattcgtca acggcgctaa ttacttcgcc
     8221 aacggcgatg ctgctggcat ctttgcctaa cagataacca ccgcctggtc cacgtacgct
     8281 ggaaaccaga ccatttttac gcagacggga aaacagttgt tccagataag aaagggaaat
     8341 tccctgacgt tcggaaatat cagccaacgg taccgggccc gcttcagagt tgagcgcaac
     8401 gtcaagcatt gcggtcacgg catagcgccc tttagatgtc agtctcatgt cttacttcac
     8461 ctcaaactcg cccctgcccg gggtttttta ttgtaaaagt gggggtattg catagcaggg
     8521 tcaagtctga cattcccgag taaattggtc aactatttac ttgactgatt tagtcgggta
     8581 tttaaccttc agtgccattt ttttatcgtg gcgtttgtac ctgttgtcgg atgcggcgtg
     8641 aacgccatat ccgccctggg gttctgtaca ctgtaggcct gataagacgc attacgcgtc
     8701 gcatcaggca acggctgtcg gatgcggcgt gaacgcctta tccgacctac ggttctgttc
     8761 actgtaggcc tgataagacg cattacgcgt cgcatcaggc aacggctgtt attcggcctt
     8821 gttaccttta ttctgctgct caatagaagc cagaatcccg cgcaggatat tcaactcctg
     8881 gctttccggg cgcgcacggg taaacagacg gcgcaattta ttcatcacct gccccggatg
     8941 gttttcacgg ataaaaccgg ttgccagcag cgtttgttcc agatgaccat aaaaacgctc
     9001 cagatcatcg accagcggat acggcgtctc ttcatgctcg acctgctcgc cgttttcctg
     9061 agttgccagc caggccatgc gcacttcata ggcaataacc tgaaccgcca tcgccaggtt
     9121 cagcgagctg tattccgggt tagccgcaat cgcgacatga taatggcatt tctgcaactc
     9181 ttcattggtc aagccgacgc gctcgcgacc aaacaccagc gccaccgggg tatttgccgc
     9241 ttcagcgacg cttttcaggc cgcattcgcg cgggtcgagc atcggccatg gcagcgtgcg
     9301 ggaacgtgcg ctggtgccca ccaccaggct acaaccggct aacgcttcgt cgagcgtatc
     9361 gacgatgtga gcattaccaa tcacatcgct ggcccctgct gccagggcaa tcgcctggga
     9421 gtcgggtttc accagtggat taaccagcca cagattggtt aatcccattg ttttcatggc
     9481 acgggcaaca gaacccatat tgccggtgtg tgacgtctcc accagcacaa ttcgaatatt
     9541 ttgcagcatt gtctttcttc atctaaagat tattcacgca tcttatcata aaacgaagac
     9601 agatgccgat ctcgctgcta tactctgcgc cgttttcccg ttctttaaca tccagtgaga
     9661 gagaccgatg catccgatgc tgaacatcgc cgtgcgcgca gcgcgcaagg cgggtaattt
     9721 aattgccaaa aactatgaaa ccccggacgc tgtagaagcg agccagaaag gcagtaacga
     9781 tttcgtgacc aacgtagata aagctgccga agcggtgatt atcgacacga ttcgtaaatc
     9841 ttacccacag cacaccatca tcaccgaaga aagcggtgaa cttgaaggta ctgatcagga
     9901 tgttcaatgg gttatcgatc cactggatgg cactaccaac tttatcaaac gtctgccgca
     9961 cttcgcggta tctatcgctg ttcgtatcaa aggccgcacc gaagttgctg tggtatacga
    10021 tcctatgcgt aacgaactgt tcaccgccac tcgcggtcag ggcgcacagc tgaacggcta
    10081 ccgactgcgc ggcagcaccg ctcgcgatct cgacggtact attctggcga ccggcttccc
    10141 gttcaaagca aaacagtacg ccactaccta catcaacatc gtcggcaaac tgttcaacga
    10201 atgtgcagac ttccgtcgta ccggttctgc ggcgctggat ctggcttacg tcgctgcggg
    10261 tcgtgttgac ggtttctttg aaatcggtct gcgcccgtgg gacttcgccg caggcgagct
    10321 gctggttcgt gaagcgggcg gcatcgtcag cgacttcacc ggtggtcata actacatgct
    10381 gaccggtaac atcgttgctg gtaacccgcg cgttgttaaa gccatgctgg cgaacatgcg
    10441 tgacgagtta agcgacgctc tgaagcgtta atgactcagg cgggtgatat cactcacccg
    10501 ccctcgcctt tcaggcgcta ttccgaaata cttcctcact gctttacttt ctttcgtcac
    10561 tctcccacca tctttccccg attaatggat gataaagaag tcgcaaggaa aggttatggc
    10621 actgccagtg aacaaacgcg ttcccaaaat tctgtttatt ctctttgttg ttgccttctg
    10681 cgtttattta gtgccgcgcg ttgccatcaa cttcttctat tatcccgacg ataaaattta
    10741 cggtcccgat ccctggtcgg cggaatccgt cgaatttacg gctaaggacg gtactcgtct
    10801 gcaaggctgg tttatccctt cttcgacggg ccctgctgac aacgccatcg caaccatcat
    10861 tcatgctcac ggcaatgccg gaaatatgtc cgcccactgg ccgctggtca gttggttacc
    10921 cgagcgtaat ttcaacgttt ttatgtttga ttatcgcggg tttggtaaat caaaaggcac
    10981 gccgtcccag gccggattgc tggacgatac gcaaagtgcc atcaatgtgg tgcgccatcg
    11041 cagtgatgta aacccacaac gtctggtgct gttcgggcag agtattggcg gggcgaatat
    11101 tctggatgtt attggtcggg gtgatcgtga aggcatacgt gcggtgatcc tcgactccac
    11161 atttgcctct tatgcaacca tcgccaacca gatgatcccc ggcagtggct acttacttga
    11221 tgagagttac agcggcgaaa attatatcgc cagcgtcagc ccgatcccgc ttttactcat
    11281 tcacggtaaa gctgatcacg ttatcccatg gcagcacagc gaaaagttgt atagcctggc
    11341 aaaagagcca aaacggttga tcctaatccc ggatggcgaa cacattgatg ctttttccga
    11401 tcgtcacggc gatgtttatc gcgaacagat ggtggacttt atccttagcg cgttgaatcc
    11461 gcagaactaa cccatgatcg ctagcacgat aatcattcac aaaaccacct taagacatgc
    11521 taatccactg gtcagaacag tttaagatga gaaaaattct gtgacgcttg ccaacatttc
    11581 tgatgattag cattcccttc gccatttcct tgagcaaact ttagctattc ttatcaatta
    11641 tgcttatggg agatctacag atgatgccta cgcttgctcc accatctgtc ctttcggctc
    11701 cccagcgccg ctgccagatc ttgctgacgc tctttcagcc ggggttgacc gccaccatgg
    11761 caaccttcag cgagcttaat ggtgtggatg atgatattgc cagtcttgat atcagcgaaa
    11821 caggacggga gatcctgcgc tatcatcaac tcacactgac gactggttat gacggtagct
    11881 accgggttga aggtacagta cttaaccaac gtttgtgttt atttcactgg ctacgacgtg
    11941 gtttccgtct gtgtccgtca tttattacca gccaattcac ccccgccctg aagagtgaac
    12001 tgaagcggcg cggaattgcg cgtaactttt acgacgatac caatctacaa gcgttagtga
    12061 atctctgctc ccgacggctg caaaaacgct ttgaatcgcg cgatattcat ttcctgtgtc
    12121 tgtatctgca atattgtttg ctgcagcacc acgctggaat tacgcctcag tttaatccgc
    12181 tccaacgtcg ctgggcggaa tcctgccttg aatttcaggt agcgcaggaa attggacgcc
    12241 actggcagcg tcgggcgctc cagcctgtac cacctgatga gccactgttt atggcactac
    12301 ttttttccat gttgcgggtt cccgatccat tgcgggatgc gcatcagcgg gacagacaat
    12361 tgcgtcagtc tatcaaacgt ctggtaaacc attttcgtga gctgggaaat gttcgttttt
    12421 atgatgaaca ggggttatgt gatcagcttt atacccacct cgcccaggcg ttaaatcgca
    12481 gtttgtttgc catcggtatt gataataccc tgccggaaga gttcgccaga ctgtacccac
    12541 gcctggtgcg caccacccgc gcggcgctgg ccggatttga aagtgaatac ggcgtccatc
    12601 tttctgatga ggaaagtggt ctggtcgcgg tgattttcgg tgcctggcta atgcaggaaa
    12661 acgatctgca tgaaaaacag attattcttc ttaccgggaa tgatagcgag cgagaagcgc
    12721 agattgagca gcagttacgc gaactaacgt tactgccgct caacattaag catatgtcgg
    12781 taaaggcatt tttgcagaca ggcgctccgc gtggcgcggc actgattatt gcgccttata
    12841 ccatgccatt accgctcttt tcaccaccgc tgatctatac ggacctgacg ctgacaacac
    12901 atcaacagga gcagatccgc aaaatgctcg aatcagcatg agggaacaac tttcgggcgc
    12961 aaaaacattg ccggaagcgc caccagcgcc attacccaga acacgccgtg gcccagatat
    13021 tgatacagga aaccggcgaa aacggtcatg atagcgatac tgccgcccat cgcgacggca
    13081 gagtaaaccg cctgtaaacg gatgacttcg ctaccctggc gagcagcaat ataacgcatg
    13141 gcggccaggt ggcagaccgt gaaggtgccg caatgcagaa tttgcaccac tatcaaccac
    13201 ggcaacgccg tagttgctcc cataatgccc cagcgcacta cgccgcaaat cgccgagatc
    13261 aacagcatat cgcgtgcact acaacggcgg aaaagtttat tactcagcgc aaagataatg
    13321 acttccgcca ccacgcccag cgaccacaaa taccccaccg ccgaggccga gtagccagct
    13381 gcctgccagt aaatggcgct aaaaccgtaa taggccgcat gtgccccctg caataaacaa
    13441 acgcaggcca gaaagcgcca gttctggcga accagcgcca accacgcaga ccaaccggtg
    13501 ctctcctgct ggcgacttgc cccttgtggc tgaatcgtcg gacggatgag aaagccgagc
    13561 agcatggatg ccacgcccaa cgtcaacagc gcgaggatca cccgataatc aaacatagtg
    13621 accagtttgc ccgtcagcgc cgagccaatg acaaacgcca ccgagcccca cagtcgcact
    13681 ttgccgtaat caagcgggaa ctgcttttgc cacgtattcg ccagtgcatc ggtcaacggt
    13741 accagtggtg agaaaaagag gttaaagcca atcatcacca gcatcagcca cgctacgtgc
    13801 gcccccgccc agaaggcgac agcaaagaga agtgtcagca gtgccagcac gcgcaaggcg
    13861 gaaatcaggc gggaaggatc gctgacgcgg ggcgcgatga gcaaactccc gaggaaacgg
    13921 gcaaccagac ctgcccccaa taacaggccg atggtttctg gcgttaaacc aatcccttta
    13981 agccagacgc tccagaaagg tagaaaaatg ccgtaactaa aaaagtatgt gaaatagccg
    14041 agcgccaacc agcgcgtgga ttgcaaaacc atgagtccct cccgtcagga ggcgttagtc
    14101 tggggttaat cgaatgttgg tgcaagttga aaaataagaa tattcgagcc tgcttcccga
    14161 tgtctgtaac gccagttcac aagcactaaa aaactgagat ccgcgacgca tgttgcaaaa
    14221 ataatgcgta attatgccgt tacgcttgcc aaacgttcct gcacaatggc gatgaaatcg
    14281 cgtaatgccg gcttcatctc ccctttcttc cacgccatca gtaaagcaat ggaaggcaca
    14341 tttccggcaa tgggacgaaa aacaacctgt ccggtattaa aattattcat ataaccgggt
    14401 atcaaagtga cgcccagccc catgcccacc agattcatgg tcaccagaat attcgttgcc
    14461 acctggacga tatttggctg gctgttttct tgcgcaaacc acgctttaac gatcggcgca
    14521 agcgaaccgg aatacaccgg atcggtactg acgaaattca cgccatccag ttgcgcggcg
    14581 gtgatctctt tttcatgtgc taaagggtga tcaaccggta acacaaccac taatggttcg
    14641 tcaaaaagct ccagataatc aatctccggg ctataaacag gatggcgcat taagccgacg
    14701 tcgagttcac cacggcgaat tttttcctcc tgttgcgtgg tgattaaact caccagctca
    14761 atcaaggtgt ctggctgtct gagacgaaac atcggtaata cttttggcag taaattcact
    14821 tccgccgatg gcacgaagcc aatggttaat tgtctgtctt cctgaacaat tttccgcgcc
    14881 cgtaatttgg cattttccgc ttgttcgagg attgccagcg cgtcctggag aaaacattct
    14941 cccgccgccg tcaacgcgac tttgcgctta tccctcacca gtaacggaac accgacacag
    15001 ttttcaagat cgcggatctg gctgcttaac gaaggctgtg aggtatgcag tttttccgcc
    15061 gcacgggtaa agttcagtgc ctgcgccact gcgacgaaat agcgtaaatg ccgtagttcc
    15121 atcaccttcc ccttgttatc gaaaaaacgt ctcagctggt agaaattaac tatttcacat
    15181 attagcaacc aaccagcaac atccttatgg cacaaaaata gaaggtcaat acatcttatc
    15241 tttcaggatt aaaaaatatg accacaccct cagatttgaa catttaccaa ctgattgaca
    15301 cccaaaatgg tcgggtcact ccgcgtattt ataccgaccc ggatatttac caactggagc
    15361 ttgagcgtat tttcggtcgt tgctggctat ttctcgccca cgaaagccag atcccaaaac
    15421 ccggtgattt ctttaacacc tacatgggag aagatgcggt tgtcgtagtg cgtcagaaag
    15481 acggcagcat caaggcgttt ctcaaccaat gccgccaccg ggccatgcgt gtgagttatg
    15541 cagattgcgg caacactcgc gcctttacct gcccgtatca cggctggtct tatggcatta
    15601 acggcgagtt gatcgatgta ccgctggaac ctcgcgccta cccacaaggg ttgtgtaaat
    15661 cccactgggg actaaacgaa gttccttgtg tggagagtta taaagggcta atttttggca
    15721 actgggatac cagcgcaccg ggcctgcgtg attacctggg tgacattgcc tggtatctgg
    15781 atggcatgct ggatcgtcgc gaaggcggca ccgaaattgt cggcggcgta caaaagtggg
    15841 tgatcaactg taactggaaa ttcccggcag agcagttcgc cagtgaccag tatcatgctc
    15901 tgttcagcca tgcttctgcc gttcaggtat taggggcgaa agatgatggc agcgataagc
    15961 gcctcggtga tggacaaacc gcccgcccgg tgtgggaaac cgccaaagat gcgctgcaat
    16021 ttggtcagga cggtcacggt agcggtttct tctttactga aaaaccggat gctaatgtct
    16081 gggtcgatgg cgcagtttca agctattacc gcgaaaccta tgccgaagca gaacaacgtt
    16141 taggtgaagt tcgcgccctg cgcctggcgg gtcataacaa tattttcccc acgctttcat
    16201 ggctaaacgg cactgccaca ctccgcgtct ggcatccgcg cggccctgat caagttgaag
    16261 tgtgggcgtt ctgtattact gacaaagccg cctccgatga agttaaagcc gcttttgaaa
    16321 acagcgccac tcgtgctttt ggtcctgctg gttttctcga gcaggatgac tcggagaact
    16381 ggtgtgaaat ccagaaattg cttaaaggcc accgcgcccg caacagcaaa ctgtgtctgg
    16441 aaatggggct tggtcaggaa aagcgccgcg acgacggcat tcctggcatt actaactata
    16501 tcttttcaga aactgccgct cgtggaatgt accaacgctg ggccgatctt ctgagtagcg
    16561 aaagctggca ggaagtgctc gataaaaccg ccgcttacca gcaggaggtg atgaaatgag
    16621 tgcgcaagtt tcactagagt tacatcaccg cattagccag tttctctttc acgaagccag
    16681 cttactggac gactggaaat ttcgtgactg gctggcgcag ctcgacgaag agattcgtta
    16741 caccatgcgc accacagtta acgcgcaaac acgcgaccgc cgcaaaggcg tccagccacc
    16801 gacaacctgg atttttaatg acaccaaaga ccagctggag cggcgaatcg cccgtctgga
    16861 aacgggcatg gcctgggcag aagagccgcc gtcacgcacc cgtcacttaa tcagcaactg
    16921 ccagataagc gaaaccgaca tcccaaacgt atttgctgtg cgggtaaatt atctgcttta
    16981 tcgggcacaa aaagagcgcg atgaaacatt ctatgttgga acgcgtttcg acaaagttcg
    17041 ccgtctggaa gatgacaact ggcgcttgct ggaacgggat atcgtcctgg atcaagcggt
    17101 aatcacttcc cataacctga gtgtactgtt ctgatgaatc gaatttatgc gtgtcccgtt
    17161 gcggatgtgc cggagggtga ggctctccgg atcgatacct cgcccgtcat cgccctgttc
    17221 aacgttggcg gcgagtttta tgccattaac gatcgttgca gccatggtaa tgcgtcaatg
    17281 tcagaagggt atctggaaga tgacgccacg gtggagtgcc cgctacacgc cgccagtttt
    17341 tgcctgaaaa cggggaaagc gttatgcctg cccgccaccg atccgctcac cacttatcca
    17401 gtacacgttg aaggtggtga cattttcatc gacttaccgg aggcgcagcc atgagcgatc
    17461 tgcataacga gtccattttt attaccggcg gcggatcggg attagggctg gcgctggtcg
    17521 agcgatttat cgaagaaggc gcgcaggttg ccacgctgga actgtcggcg gcaaaagtcg
    17581 ccagtctgcg tcagcgattt ggcgaacata ttctggcggt ggaaggtaac gtgacctgtt
    17641 atgccgatta tcaacgcgcg gtcgatcaga tcctgactcg ttccggcaag ctggattgtt
    17701 ttatcggcaa tgcaggcatc tgggatcaca atgcctcact ggttaatact cccgcagaga
    17761 cgctcgaaac cggcttccac gagctgttta acgtcaatgt tctcggttac ctgctgggcg
    17821 caaaagcctg cgctccggcg ttaatcgcca gtgaaggcag catgattttc acactgtcaa
    17881 atgccgcctg gtatcctggc ggcggtggcc cgctgtacac cgccagtaaa catgccgcaa
    17941 ccggacttat tcgccaactg gcttatgaac tggcaccgaa agtgcgggtg aatggcgtcg
    18001 gcccgtgtgg tatggccagc gacctgcgcg gcccacaggc gctcgggcaa agtgaaacct
    18061 cgataatgca gtctctgacg ccggagaaaa ttgccgccat tttaccgctg caatttttcc
    18121 cgcaaccggc ggattttacg gggccgtatg tgatgttgac atcgcggcgc aataatcgcg
    18181 cattaagcgg tgtgatgatc aacgctgatg cgggtttagc gattcgcggc attcgccacg
    18241 tagcggctgg gctggatctt taaggaagca cgatgaaaga aaaaacgatc attattgtcg
    18301 gtggcgggca agcggcggca atggctgcgg cctcgctacg ccagcaaggg ttcaccggtg
    18361 agctgcatct gttttccgat gagcgacatc ttccttatga acgacctcca ctctcgaaat
    18421 ccatgttgct ggaagattcc ccgcagttac agcaggtgtt acccgctaac tggtggcagg
    18481 aaaacaatgt tcatctgcat tccggtgtaa ccatcaaaac gctgggtcgc gacacacgag
    18541 agttagtgtt aaccaacggc gaaagctggc actgggatca gctttttata gcaaccggcg
    18601 cggcagctcg accgctgccg ttgcttgatg cactgggaga acgctgcttt accctacgcc
    18661 atgccggtga tgccgccaga ctgcgagaag ttctgcagcc cgaacggtca gtcgtgatta
    18721 tcggtgccgg aactattggt ctggaactgg ctgccagcgc cacgcagcgc agatgtaagg
    18781 tgacagtgat tgaactggcg gcaaccgtca tgggccgtaa tgcaccaccg cccgtgcaac
    18841 gctatctttt acagcgccac cagcaggctg gtgtgcgcat tctgctcaat aatgccattg
    18901 aacatgtggt cgatggtgaa aaagtagaac tgacgctgca aagtggggaa acgcttcagg
    18961 ctgatgtggt gatttacggt attggtatca gcgccaacga gcaactggct cgcgaggcca
    19021 accttgatac tgccaatggc attgtcattg atgaggcttg ccgcacctgc gatcccgcga
    19081 tctttgccgg tggcgatgtg gcaatcactc gtcttgataa tggtgcacta caccgctgcg
    19141 aaagctggga aaacgccaat aaccaggcgc aaattgccgc tgccgcaatg ttagggctac
    19201 cgctaccgct actgccgccg ccgtggttct ggagcgatca gtacagtgat aacttacagt
    19261 ttattggcga tatgcgtggc gatgactggc tttgtcgtgg caacccggaa actcagaagg
    19321 cgatttggtt taatctgcaa aacggcgtgc ttatcggtgc ggtcacgctg aatcaggggc
    19381 gtgagattcg cccaattcgc aaatggatcc agagcggcaa aacgtttgat gcgaaactgc
    19441 tgatagatga gaacatcgcg cttaaatcac tgtaaccagg ataattagcg aatatctcaa
    19501 tgcctggggc gtggcgaggt gcaagagtgt gtattacgtt taaatcacat tatcttgcaa
    19561 agggattggt tatgaacaca ctacgttatt ttgattttgg agctgcccgc cccgttttgt
    19621 tattaattgc ccgtatcgcc gtggtcttaa ttttcattat ttttggtttt cccaaaatga
    19681 tgggctttga cggtacggtc caatatatgg cctcgttggg cgcgccaatg ccgatgctgg
    19741 cagcgattat tgcggtagtt atggaagtgc ccgccgcgat attaatcgtg cttggctttt
    19801 tcacccgtcc gctggcggtg ctgtttattt tctacacgct gggtacggcg gtgattggtc
    19861 accattactg ggatatgacc ggcgatgcgg ttgggccaaa tatgattaat ttctggaaga
    19921 atgtcagtat cgctggcgcg ttcttgctat tggcaattac cgggccgggg gcaatttctc
    19981 tcgatcggcg ttaggaaaga tgccggatgc ggcgtgaacg ccttatccgg catttaataa
    20041 attacagcca ctctacccgc aacgacatct ctgaagttgt tgattcccct ggtgctagcg
    20101 caatgagatc acccccttcc gggcgatgat gatcatccgg cgcatggctc atcggttcca
    20161 gacagaagaa atcaaacgca tatcctttat caaacgcagg gtcggaaaca aagatgaaat
    20221 aacacggtgc aggtggcgtc gtttccatga tgatggcata accttcctgc ggctgctcga
    20281 tgcgggcctg accattccat ccggcaaaac cattgttcac ccactggcgc ggcaacggcg
    20341 cgggctggtt aaaatccagt tcctgcggta gctgctcgca aaactcaccc gccagccact
    20401 gctcccgctc cagccagtaa ccgctcgcct gtgcctgaat ccgcgtttgc ggcgacaacg
    20461 gaaaataagg atgccagccg gtaccaaatg gcagcgtctc tgccccttga ttggtgacag
    20521 agagcgtcac cgtcagcgta tccgccgtta aatgaaacgc ctgacttacc cgatagtgat
    20581 agacaccgct gcgatgttca tacaccagac acaaactatc atcgctgtgc gagacacatt
    20641 gccactcgcc cagccagcca tcgccgtgta gatagtgcgc atcccactca acattcggtt
    20701 gcagttgata ctcacgcccc tgccagacaa aacgattgcc gctcacccgg tttgcaaatg
    20761 gcaccagcgg aaaacatgag gcatcggttg ccacaccgct ttttttacca ggacgtaaga
    20821 gcggcgtcgt atcgcgccag aagccttcga ttacgccgcc ctggtcagaa acgtccagct
    20881 ttagcgaccc gtgggataag gtatagatgg tcatccgcta actccttaat ccgggaagtt
    20941 aatcacaact ttcccgcatt tgccgctcgc catcagcgca taggcatcac ctgcctgttc
    21001 cagcgagaag cgatgggtaa tagcgttacg cggccacagc ttccagtccg tcagatcatg
    21061 ggcgcatttt tccatatgga acagactggt cacccaggag ccgataatcc gccgttgatg
    21121 gtgcatcaga tcggcgctga cctcgaattc cacttttccg gtttcaccaa tgtaaaccac
    21181 ccgtccccag tcagcggtgg attgcagtgc cagcaagcga cctgcggcat taccggaaca
    21241 atcgagcgca acatccgcgc caccgtgggt gagttcggcg ataatctgcg gcagaccttc
    21301 ggtggttgct aaatagccgt gatccatcac ccctaactgt tttgccatcg ccagacgttc
    21361 cggcagcata tcaacgccga tgatccgttt tgcaccgcga cctttcgcca gcatcatcgc
    21421 catcatgccg actggcccca gaccgaccac cagcacgtta tcactgccgg aaacttcgcc
    21481 gcgcaaaatt ccttcatacg ctgtaccaac gccgcaactg ataaacgcac catcttcgta
    21541 gctcagcgca tccggcagga ggatcagatc tttttcttcc gccagcaagt attcggcatg
    21601 accgccgtca cgctgccagc cgtaagccgc ttttccttcg ccagtacaag aaataggaaa
    21661 accgcgacgg cagttcgggc aaaaaccaca gccagaaatg tgatacacca gcacgcggtc
    21721 gccctcttta aaatggcggc agccttgccc catcgccaca atctgcccgc acggttcatg
    21781 accgttgata aagccctggt ataacggttt atcgggtgcc gccgctgtgg cacggtgttg
    21841 atgatagata tagtggacat cgcttccgca aatcccggag gatttcattt tgatcagtac
    21901 ctggttaatc cccggcgtcg gcaccgcaac ttcccgcaga tcgacggtcg aatttcctgg
    21961 taaataagct gccagcatcg ttttcataaa tccctcatta acaatacgat taattttcat
    22021 ccctgccgca cccgcgccag gggcgttaag gtttagcgtt tcgctttact gcttcgctgg
    22081 gtcagcaaga tattcgccag caccgccacc acgatgatga cgccgcgtac cacctgctgg
    22141 aaaaaggagt taataccgag cagcaccaga ccgttaccga ttagcgtaat caccagcaca
    22201 ccaagcaatg taccgaacag ggaaccgcga ccgccggaaa gtgccgtacc gccgaccacg
    22261 accgcggcga tgacgtcaaa ctccagaccg tttgcggcac ctgcgttacc agaaccgagg
    22321 cgcgccgcca acaaaatgcc ggtcaccgcc gctaataatc ccgaaagggt aaagataaga
    22381 atgcgcaccc gacgaacgtt gatgccgcac aactgcgccg ccgtagcatt accgccaacg
    22441 gcaaaaaccg agcgcccgaa ggcggttttg cggctgatga acacaaacag cgcaaacaac
    22501 acaatcatga tcagcgcgga taccggcaca ccgagaaatt gtccgcccag ccagtccagc
    22561 acctcgtttt catcaatcgg cactggcagt gcgttcgtca taaacagccc cattccgcgc
    22621 agggcgctcc acagccccag tgtggcaacg aaacttggta cattaaacac gccgcgcagc
    22681 accccggcca gcgttcccat cagcgcgcct aacagcaaca ccagcaggca cgccaccgcc
    22741 agcggaactt caaattgcag caaaaatgcc aggcacaccg agacaaaagc caccatcggc
    22801 ccaacgctga catcaatttc accggagata ataatcagcg tcatcgccca ggcggcaatc
    22861 ccaatggtgg cggcatcgcg cagcacgttc atctggttat tcaatgagat aaagccaggc
    22921 gcgttcaggg agaagaccag ataaagaatg gcaatcacca ccagcaaacc gatctcatta
    22981 atatggcgac tgacaaattg tttgagcgag acgctcttgc cctgcggcaa tggtaatgac
    23041 gaagcagaca tcttcaggtt cctcggtaaa attcatcagt gcacagacag aatggcggac
    23101 atcagctcat ccacattgac cggagcgtga aactcctgcg agaacgtgcc gtgctgtaat
    23161 aacaggatgc ggtcacacac cagcggcaac tcctccactt cactggagat aaacaccacg
    23221 ctttttcctt cggcagccag ctcacggaca atacggtaaa tctgctgttt ggcttcgata
    23281 tcgacgccgc gcgttggctc gtcgagcaac aaaatctggc tggcagcata gacccaacga
    23341 ccgatcacca ctttttgctg attgccacca gaaagcgtgc cgatgggtgt ttcgctactg
    23401 gcggccttga ccgtcatccg ctgcatcacc tcttcggtca ggcggcggat ggtggaccat
    23461 tgcagcacac cgttggcgct gattttttgc cgattggtca gcactgtatt ttcgtcaacg
    23521 cccaaccagg gaatgatccc cgcttctttg cggttttctg gcgtatagcc aatgccgcgt
    23581 ttcagcatgt cgccgtaatc ggggcgcgtg attttctcgc cgttgataac aatttcgccc
    23641 tgttcatact cctccagccc aacaatcgcc ttcagcaatt cactgcgccc tgcccccagc
    23701 agaccagcaa tgccgagcac ttcgccacga cgtagcgtaa aactgatatc ctccagcttg
    23761 ggcttatggc gtaacgcacg gacttccagc acggcctgat ccacaatttc ctgaggggct
    23821 accggcgcaa tatcaacgtg atcgcgcccg agcatcagcg acacaatatg atgcgtggag
    23881 gtgttttcga gcatcacatc gcccgccacc tgaccatcgc gcataacggt ggcacaggag
    23941 gcaatgcggc gaatttcttc catccggtgg ctgacataaa tcaccgccac gcccagtgcc
    24001 gacatctttt tcaccgcgct gatcaccagt tcaacttccg cactcgcaag cgaactggta
    24061 ggttcatcaa gaatgaccac gcgcggctcg cccttcatca cccgcgcaat ttccaccagc
    24121 tgcttttgcg ccgggcttag tgttgaaaca agttgttcag gactaacgtc aacgcccaac
    24181 gcctgtaagc aacgttgggc atcctgcgcc atttgcaggt aatcaatcat gccgttgcgg
    24241 cggggccact gaccgaggca gaggttttcc gccaccgtca gcccttccac cagacttaac
    24301 tcctgataaa ccgcgcgtac ccccagttca gcggcacggc gagtcagcgt agcttcgtcg
    24361 ccttccagtc gcgtctcgcc aatccagatt tcaccgctat ccgggcgttc gctgccggta
    24421 agcattcgaa tgagggtcga tttgcccgcg ccgtttttac ctagcagtgc acgaacttcg
    24481 cctttattga gcgtgaagtt aacgttatcc aacgcaacga cgccgggata acgcttattt
    24541 cctgccacca cttttgctac cgggactgcc tctgttgccg tgaacatagg gacctctgcg
    24601 aatcagcgat tagggcagac catcaacgtg cgttgccagc cactgtttac catcttccgt
    24661 tttggtatag agatcgatag gcacctgaat cactttttca ccgtcggctt gtttattgat
    24721 aaccttcaat gtttgcgcga aaacagcatt gcccattttc ttaccggaaa tatccactac
    24781 cgctttcagc acctgattgt tttccagctc ctgagcaatt tcggttgtca tatccgaacc
    24841 gaaaacagca atttttccgg cctgattttg attacgtacc gcttttaccg cgccgagtgt
    24901 cgcaccgccc gactccccca taatggcgtt gagatccggc gtggagataa tcagtttttc
    24961 accaacggaa atcgctttat ctaaaacagt cccttcctga ttagcgacaa tttgcgcgcc
    25021 gggaacgcgg gattttaata cttcttcaaa tcctttacgt cgctgcacac aaacttcaaa
    25081 ggcttcgcaa ttgatgacgg caattttcgg ctggtcaatt ttattggcaa taaaataatc
    25141 ggcggcagcg ttacccagtt ttttaccaaa ttccagcgga tcgccgacca gatacgccga
    25201 gacatattta tcgaccccct tttgattaat acaggtgttg tagcaaatca ccggaatacc
    25261 cgcttcactg gcgcgacgaa cggtacggct actgccattt tcagacactg ccgataaaat
    25321 aatggcatcg acattacgcg ccacgagggg atcaacaaag gtactttctt tcgaaatatc
    25381 acccagggcg ttagtttcaa ttaactgtac ctgtactgaa gaatcttttg ccgcatcctg
    25441 aacgccctga cgcactccag cgtaatatcc ctgggtatca aggtatattg caccaatggt
    25501 catttcttta tccgcagccc tggcaaatag tgcgctacct aatagcgtag ccattaataa
    25561 tagattacgg gttgttctca tttttttagg catagtgcct cctgtagggt ttttattaac
    25621 aacggcttat tctaattatt ttgtgatgag cggcagcgcg tgccgctcaa atattacagt
    25681 taatagggtt tagtgaacgt agttaaaaat aaaaggcatc acagtggtga ataatgccgc
    25741 tttcggccag gccggattaa tcgccgtcaa ttcagcgcga gcagactcat attgcgcaac
    25801 ctccccgagt cccgcggacg ccagcatcgc caccatcagg catttttctt tatgctgctg
    25861 ttgtaaatcg ccatacagcg ataacaggtc aggttgtgaa acagcaaaga aatccgcctc
    25921 aatactggtt ttcgccatct cttgcgccca ctgtttcatt tcactaaaca gttgctgtgc
    25981 ggtttgctgt tcacccagca gtcgcagcgc cattccttgc cagaagagat aatcaaccgg
    26041 ctgatcgttg taataactgt ggatgttaat ggtgcgatcg ccggtcgccg ccagacgtaa
    26101 acaacgcatc gcttcagttt catcgccctg cgcgttggcg catatcgcct gccagaacca
    26161 gatgtcgtta tcagtttgcc ccggtaaacg gccttcgctt aaattctccg gataatgcag
    26221 cgcggcatga agcagttcgc tggcctgctg cggctctctg gcatcaagat gctgccaggc
    26281 gcgtaataac tggttgagga taaactgact ggtgaccttc ccttccccgc cttcccacgg
    26341 gtggaattta cgcgtggcga gaatgtccgc cgctttgtct gcctgacccg tgagatgcca
    26401 caaattgagc agttctgcgg tcatgtcgtc gcgtttcagc gcaatttcca gattattttc
    26461 cagacgcgcc agtcgtttct ccggtgtggc tccacttaac ttatcaagca aatcccgttc
    26521 gaaaagcaga cgtgcatcct gcggcgcaag ctgataagca ttatcaagat aacgcgcggc
    26581 cagctcatca tcgtgttgct tattccacgc atggatcgct aacccgcgcc agccgtcggc
    26641 aaactccggc gacatctcta cgcaacgttg ccaaaaggca atggctttgt tgtagctacg
    26701 tttgttgtag tagaagcagg ccagtaaatg gcgagcaaac cagcactctt caatactctc
    26761 cagcgccgcc acttcttcca gcgtattcgg gaaacggaca aactgcggga agacatcaat
    26821 ggcttttgcg accagttcgc cacgttcggc tttcggcagc aagctggctt gcaggtaaag
    26881 cggcagcgtg cgctggcagt ccagtgcgtt cagcatctct gccgccaggg tgggcattcc
    26941 ccagttaatc agttgcccgg cggtcatcag ggcgttaacg tcgcgtccct gacacagacc
    27001 gcgccactgc gcgagggctg attcgctacg accatcgaac cagttcagcc accacagagt
    27061 ggcgttcagc ggataatcgc gcagcagttt ctcgcgctgc acacgcgcgt tgtcctgacg
    27121 accacttaac accagcagca gattatgcag gcaaagcact tcctgattgg ttgggcaggc
    27181 gcgaagactt tgttggcaaa aatccagacc agcgtcgaag ttaccattac gcgccgccag
    27241 tcgtgccagg ccataatagc caccggcttt gctgttgccg ctccagaccg cacgccagaa
    27301 atcctcttcg gcttgttgat attgtccctg acgttcgtaa gcactggcgc gaatcaaact
    27361 cgcctgtccg cactgcggat ttttgttcag cgcatgtgcg cgtttcagag cctgagtggc
    27421 atacgccacc gcttgcggga aatctgcgcg gttatattcc agcatcgcca gcgccaggtt
    27481 acagcggtaa tccagcggat ccagcgccac gccgcgcagg tagtaatcga acggtgaacg
    27541 gctggcgtga tgatattgct ccagatgctg accgataaac caggcttcat ctgtactggt
    27601 aatgtcttgt gctgccagtg gcgctttggc gacgtccggc aacggcaact cttgcggctg
    27661 atgttcctga taactcagta caatattgcc gtcggcatcg gagagctcaa tggtcagcct
    27721 ttcaggattg ataccgtgca acacgccctg gatggcggtc gcaggcatca gtgccacggc
    27781 atcatcaagt aacgcgttgc atttgccgat ttcgcggatc gccaggcggt atccgttcaa
    27841 cggagagatg gcataaagcc cccactcaat cccccgctca ctacgctgga gttttatcac
    27901 cgcatcgcgg gaggcatttt gcaccatgcc caaagaatga taaggcagga aatactgctc
    27961 aaaacgcttc tcttcgtaag catcaagcca ggtaaaatca ggctggttat cggcaaaaat
    28021 accggtcatc agttcgatat acgggccgtt attgtcggtc agactcttat cccacgcctg
    28081 gccaaattca ctgtgtcccc agctccactg ctttttacct ggcgcaatat ggtggttggc
    28141 aacgtgtagc aaaccaccat cttcatcgtg acaccacgcg ccaacaaaat cgtactgtga
    28201 tttttcagcc atatatgagg ttggaacggg cacattttta tagcgagaaa tgtccactcc
    28261 agcggagtag tccactttgt agtaagtgcc ggtggcgatg gggaaagcgg agacggcccg
    28321 tttgccgtga tcaaacaccg cagtcacatc cggcgggaaa acgctctgat gcccttcccc
    28381 ccctttcact gccgggttgg cccaccacaa gaaatgacgc ggcgtggcgt tgccgttata
    28441 gacgcggctg gcgatttcca gcgccgcccg gtcagggcgc agggtgaaac ctgtcatcac
    28501 ctgtaaacca tgcatcggct ccgtttcgcc gacccacacc gtctgtgcgc cgtcttcatg
    28561 ggcttcgagg gtgaaatcaa cgggcataaa ggtggtcggg cgatggtgtt gcggccagtt
    28621 aaactcaatc ccgccagaga tccacggtcc cagcagcccc accagcgcag gtttaatgac
    28681 ttcattgtga tagacaaaat cgcgctgttt cactttatcc catgcgcgat gcacccgacc
    28741 gcccagttcc ggcaggatca tcactttgat gtagtcgttt tccagccaca ccgcctgcca
    28801 ggatttcagg gttttctgct cgctcagcgt atcggtcacg ccgtagggat aaaccgcgcc
    28861 ggacgatccc tgataaacgc gattttccag gaacatagga tgtatatcct gcggcccggt
    28921 ttcataggtc gggatctcaa cgcgctcttg ccacactttt actggagtca tggtgccctc
    28981 aatattaaca agacatactg aattaaaaga tttgtggcag tgtattgaac aatctggcaa
    29041 tgttttcgcg gaataatcac gcaattaact aaacaaggtt tagtgaagat gagagcctgc
    29101 attaacaatc aacagatccg ccaccataac aaatgcgtga ttctggaact gctgtaccgg
    29161 caaaagcgcg ccaataaatc aacgctggcc cggctggcgc aaatttcgat tccggcggtc
    29221 agtaatattt tgcaggaact ggaaagcgaa aaacgggtgg tgaatatcga cgataaaagt
    29281 cagacgcgcg ggcatagtag cggtacatgg ctgattgcgc cggaaggtga ctggacgttg
    29341 tgcctgaacg tgacgcccac cagtattgag tgtcaggttg ctaatgcttg tttaagtccg
    29401 aaaggcgagt ttgagtattt acagattgat gcaccgacgc cgcaggcgct gctgtccgaa
    29461 atcgaaaaat gctggcatcg ccaccgtaaa ttgtggccgg accgcaccat caatctggcg
    29521 ctggcaatcc acggtcaggt tgatcctgtg accggcgtgt cgcaaaccat gccgcaagcg
    29581 ccgtggacaa cgccggtgga ggtgaaatat ctgctggaag agaagctcgg cattcgggtg
    29641 atggtcgata atgactgcgt gatgctggcg ctggcggaga aatggcaaaa taattcgcag
    29701 gaacgggatt tctgcgtgat caacgttgat tacggcattg gctcgtcgtt cgtgattaac
    29761 gagcaaattt atcgcggcag tttgtatggt agcggacaga ttggtcacac catcgttaat
    29821 ccggatggcg tcgtctgcga ctgtggacgt tacggctgcc tggaaaccgt cgcctcgtta
    29881 agtgcattaa aaaaacaggc gcgggtatgg ctaaaatcac aaccggttaa tactcagctt
    29941 gatcctgaaa aactgacaac cgcgcagtta atcgctgcct ggcagagtgg agaaccgtgg
    30001 atcaccagct gggttgatcg ctctgccaat gccattggtt tgagtctgta taacttcctc
    30061 aacatcctca atattaatca gatttggttg tacggtcgca gttgtgcctt tggtgagaac
    30121 tggcttaata ctattattcg ccagacagga tttaacccgt tcgaccgcga cgaaggaccg
    30181 agcgtgaaag cgacgcaaat tggctttggg caattaagcc gcgcccaaca ggtgctggga
    30241 attggctatt tgtatgttga ggcgcagtta cgacagattt gatggcgcga taacgtagaa
    30301 aggcttcccg aaggaagcct tgatgatcat aaacgaaaaa ttgcctgatg cgctacgctt
    30361 atcaggccta cacggagatt gcaatatatt gaatttgcaa gattttgtag gcctgagaag
    30421 gtgttcatgc cgcatccaac atgaacaacg agcacattgt cagcaaatca ccgtttcgct
    30481 tatgcgtaaa ccgggtaacg tgcgcagatg tcgagaactt tacctttgat gcgctcgata
    30541 acggcttcat cattgatgct gtccagcacg tcacacatcc agccagccag ttctttcgct
    30601 tcggcttctt taaagccgcg acgggtaatc gccggagtac ccacgcgaat accggaggtc
    30661 acaaacgggc tcttcggatc gttcggtacg ctgtttttgt tgacggtgat gttagcacgg
    30721 cccagagcgg cgtctgcttc tttaccggtc aggtttttat caaccagatc aaccaggaac
    30781 aggtggttat cagtgccgcc ggaaaccact ttgtagccgc gttccaggaa cacttctacc
    30841 atcgctttag cgtttttagc gacctgctgc tggtaagttt tgaactcagg ctccatcgct
    30901 tctttcagag caaccgcttt accagcgatt acgtgcatca acggaccgcc ctgaccacca
    30961 gggaaaacgg cagagttcag ttttttgtac agctcttcgc taccaccttt cgccaggatc
    31021 agaccgccgc gcggacccgc cagggttttg tgagtggtgg tagtaacaac gtgagcatga
    31081 ggaaccgggt tcgggtagac gccagcagca accaggcccg caacgtgcgc catatcaacg
    31141 aacaggtaag caccgatgct gtcagcgatt tcacgcattt tcgcccagtc caccacgccg
    31201 gaatatgcag agaaaccacc gataatcatt ttcggcttgt gttctttggc ttgtttttcc
    31261 agatcggcgt agtcgatatg accggtagca tcgataccgt aaggaacgat gttgtacagt
    31321 ttaccggaga agttaaccgg agaaccgtga gtcaggtgac cgccatgcgc caggttcata
    31381 cccagaacgg tatcacctgg ttccagcagc gcggtgtaga ccgcaaagtt agcctgggag
    31441 ccggagtgcg gctggacgtt agcgtagtca gcgccgaaca gttctttcgc acgatcgatc
    31501 gccagttgtt caacgatatc aacatactcg caaccgccgt agtagcgttt gcccggataa
    31561 ccttcagcat atttgttggt cagctgagaa ccctgcgcct gcattacgcg cgggctggtg
    31621 tagttttcgg aggcgatcag ttcgatgtgc tcttcctgac gtactttttc ctgctccata
    31681 gcctgccaca gttcggcatc ataatcggca atgttcattt cacgctttaa catccgcatc
    31741 tcctgactca gctaacaata aaatttttgg cctttatagg cggtcctgtt ggacaacggc
    31801 gaacagtata accgaatcat tgtgcgataa caggtcttga caaaggaatt tacgcaaacg
    31861 attaccttca ggctacacaa ggctttggag aataaagagc ttgcaaccgg aaacggattt
    31921 cttttcaggt ttgtgatgca aatttttcac ttcatcacat tctttctgaa aaacaccaaa
    31981 gaaccattta cattgcaggg ctatttttta taagatgcat ttgagataca tcaattaaga
    32041 tgcaaaaaaa ggaagaccat atgcttgacg ctcaaaccat cgctacagta aaagccacca
    32101 tccctttact ggtggaaacg gggccaaagt taaccgccca tttctacgac cgtatgttta
    32161 ctcataaccc agaactcaaa gaaattttta acatgagtaa ccagcgtaat ggcgatcaac
    32221 gtgaagccct gtttaacgct attgccgcct acgccagtaa tattgaaaac ctgcctgcgc
    32281 tgctgccagc ggtagaaaaa atcgcgcaga agcacaccag tttccagatc aaaccggaac
    32341 agtacaacat cgtcggcgaa cacctgttgg cgacgctgga cgaaatgttc agcccggggc
    32401 aggaagtgct ggacgcttgg ggtaaagcct atggtgtact ggctaatgta tttatcaatc
    32461 gcgaggcgga aatctataac gaaaacgcca gcaaagccgg tggttgggaa ggtactcgcg
    32521 atttccgcat tgtggctaaa acaccgcgca gcgcgcttat caccagcttc gaactggagc
    32581 cggtcgacgg tggcgcagtg gcagaatacc gtccggggca atatctcggc gtctggctga
    32641 aaccggaagg tttcccgcat caggaaattc gtcagtactc tttgactcgc aaaccggatg
    32701 gcaaaggcta tcgtattgcg gtgaaacgcg aagagggtgg gcaggtatcc aactggttgc
    32761 acaatcacgc caatgttggc gatgtcgtga aactggtcgc tccggcaggt gatttcttta
    32821 tggctgtcgc agatgacaca ccagtgacgt taatctctgc cggtgttggt caaacgccaa
    32881 tgctggcaat gctcgacacg ctggcaaaag caggccacac agcacaagtg aactggttcc
    32941 atgcggcaga aaatggcgat gttcacgcct ttgccgatga agttaaggaa ctggggcagt
    33001 cactgccgcg ctttaccgcg cacacctggt atcgtcagcc gagcgaagcc gatcgcgcta
    33061 aaggtcagtt tgatagcgaa ggtctgatgg atttgagcaa actggaaggt gcgttcagcg
    33121 atccgacaat gcagttctat ctctgcggcc cggttggctt catgcagttt accgcgaaac
    33181 agttagtgga tctgggcgtg aagcaggaaa acattcatta cgaatgcttt ggcccgcata
    33241 aggtgctgta atttgatgtt gccggatgga aacatccggc aacccttgac gcggtttaaa
    33301 ttgccgcgtc gtcctcttca ccggtacgga tgcgaatgac ccgtgccacg tcaaagacga
    33361 agattttacc gtcaccgatt ttgccggttt gcgccgtgcg aataatggta tcgacacaga
    33421 tatcgacaat gtcgtccggt acgacaatct caattttcac tttcggcaga aaatccacca
    33481 tatactccgc gccgcggtac agctcggtat ggcctttctg gcggccaaaa cctttcacct
    33541 cagtgaccgt catgccggta atgccgactt cagccagtgc ttcgcggaca tcgtccagct
    33601 tgaagggttt tataatcgca tcaatctttt tcatgctatt ccttgaaaag gtcgcctgtc
    33661 ttttgatctg ctaaacgtaa cacataacgc caattcattc cttgaaatcg tttgcatcca
    33721 gctcgtgtcg ggaaagcagt ttataaaatt ctgtccggtt gcgccccgcc attctcgccg
    33781 cgtgggtgac gttgcctttg gtaatttgca gcagcttacg caaatagttg agttcaaact
    33841 gattacgtgc ctcaacaaag gttggcagcg ccgtgttttc accctccagc gcctgctcta
    33901 ctaatgcatc gctaataacc ggagatgagg tcagcgccac gcactgttca atcacgttga
    33961 ccaactggcg cacattaccc ggccagctag cggtcatcag gcgtttcatc gcatcagtgg
    34021 agaacgcgcg gacaaacggt ttatgtcgct ctgccgcctg gcgcaacagg tgatttgcca
    34081 gaagcggaat gtcttctgtg cgctctgcca gagccggaat tttcaggctg acaacgttga
    34141 ggcggtaata gagatcttcg cggaattccc cgcgcgccat cgcttttggc agatcacggt
    34201 gagtggcaga aataatccgc acattgatat caatatcgcg gttactgccc agcgggcgca
    34261 ctttacgctc ctgcaacacg cgcagcagtt tgacctgtaa cggcgcaggc atatcgccaa
    34321 tttcatcgag aaatagcgtt ccgccttccg ccgcctggaa taaaccttcg cgattgctga
    34381 cagcgccagt aaacgcgcca cgcgcatgac caaacagctc cgactccagc aattgctcgg
    34441 gcaatgcgcc acagttaata gcaataaatg gtttgctgtt gcgcgggctg gcgttgtgga
    34501 tagcctgggc gaaaatctct ttcccggtgc cgctctgacc gttaatcaaa acgctgacgt
    34561 ctgattgcgc caccagccgc gcctgttcca gcaaacgcag catcagcggg ctgcgggtga
    34621 caattgcctc gcgccagcgt tcatcggtgg ctggcgcgga ttgctccagc gcatcgtcaa
    34681 ttgcctgata tagcgcgtct ttgtcgacag gcttggtgag gaaactaaaa acgccctgct
    34741 gtgttgcagc aacggcatcg gggatagaac catgcgcagt aagaataatt actggcattc
    34801 ccggctgcac tttctggatt tcagcaaata gctgcatacc gtccatttca tccatccgca
    34861 ggtcgctgat aactaaatct actttttcgc gattcagtac ccgtaatcct tcagcgccac
    34921 tttccgccgt gaccacactg tagccttcgc tggtcaggcg caggccaagc agtttcagca
    34981 atcccggatc gtcatcgacc aataataaat gcgcaggttt atggctcatc aggagtgacc
    35041 tcatgggtgg atggcgcggg cttttcactc tcgtgcggcg tatccggcga gaaatttcca
    35101 gccggtttgc gggtcgagag ctggcgttca atatcggtca ggttttccag cttgcgggtg
    35161 gtgagttcca gttgctgctg tagaacgtga tgttgctggc gcaatgtatc cagctcgctg
    35221 tcgctggact gctggagttt actgtaacgt tggcgctctt ccgccagttg cagttgcagc
    35281 gcctgaccgt cgcgccagag ttgatacagt gggcgaacct gtgccgggat ctcggtactt
    35341 aacgcttcaa tacgcgcgac cagctggcgg cgctcatacg gcgtaatttt ggcgtcggcg
    35401 agcaaaatcc cttgtttaaa ggtattttgc cagctgccgt cgtcatattg gcgagcttgc
    35461 tgacgcgact gcgcaggcat taaacgatca gcacaatcca tcgcccgcag ccagtaaagc
    35521 ggattggttt cggttgattt accttgcagc gcccagatgt cgctacattc agtagaaaga
    35581 tagtcagcca gttgataaac cggaattttt tcttctgctg gcgtatcaat ggctggctta
    35641 ttgtgattct gcacgcaacc cagcaatgcc agacatggca gccctgccag ccacagccgt
    35701 cggggcaata atcgttgaaa aatgtgtcgc atattcacca gacttaaagc ctatcccagt
    35761 gggcgtaatt gttgcagaca gtctggacat ggacagcgcg gagaaaccgg agcgtacata
    35821 tcgtacgtga agatttcgag cactgcccgg ggccgaactg acaaataaaa tagcctgata
    35881 ggataggctg ttagcattat ttcgtgtttt tcgacgacgg taattcaatg cggaaacaaa
    35941 cgtcttgccc gctctcgtcg accagataca gttccccttg catacggcga atacaatccc
    36001 tggcaatgct taatcccaga ccgctgccct tcaccgcccc ttttcgctgg tggcttccct
    36061 gaaaaaaggg ttcgaagatc atggcgcgtt cctcttgcgg aatgggcgtg cctgtattga
    36121 tgacatcaat ataaacccgc gcaccatgtg aactgctgcg aaggcaaatg ttaccggatt
    36181 cagccccgta gtgcaccgca ttggagtaaa gattatccag tacgctcatc agcagcattg
    36241 gctccgccag gcaagctgtt gctttgagat cgacgtcggt atgcatcatt ttagcccgtg
    36301 cgggcaggct atgagcagaa accactgtct ccaccagcgg tgctaactca acattctcca
    36361 gttccaccgc actgtccgcc tgtttacggt tgtaatcaag cagttgttcg atcagttttt
    36421 gcaaattgcg gctgctgcta tcaagaatgc tcaccacctc tttttgctct ggcgtaagcg
    36481 gcccgacaac ctggtcagcc agtaattcag tgccctcgcg catactcgcc agtggcgttt
    36541 ttaattcatg agataaatgt cttaaaaatt gatggcgttg ggattccagc catgacaggc
    36601 gctcacttaa ccaaagaata cgttgcccaa ccgagcgtaa ctcgctcggt ccactgaacg
    36661 agacgctatt gcccagagaa cgcccttccc ccagacggtt gatcatgcgc tcgatatttt
    36721 tcaccggccc gataatcatc cgcgtgaaaa gcagtaccat taccagactc accagaaata
    36781 gcaccagcga ttgccaacca aaatattgcc cacgttcggc gatttcacgc tgaagctgct
    36841 gcccacgaga gaacaccact gtgcgcgtgg cctgtaccat ttcggtattg gcactggcaa
    36901 aggcttcaag acgtgcggcg gcggcagcat cgggaccgct gttgttacac tgaagttgag
    36961 ccagattgtg caaatcctga cgtaatgcct ggtagagttt atcgtccggc agcacgcctg
    37021 cgtgggcatc gagcatttcg ctgtaacgct tgcgctggct ttgataaacc ttcgccaggg
    37081 ttgggtcgtc cagcacgcaa tactgacggt aactacgctc catctccagc gccgcgttgg
    37141 tcatcgcttc actgcgccgg gcatcaataa gcgtagtgcg gttaaccagc gccgcctgat
    37201 cgctaagcgc attcaggctt tgccaggctt gccatgccag caccaacagg ggcagcagaa
    37261 tcagcaaaaa tgccagcatt accagttgtc gtaatgagcg gggaaaaacg ggccagcgtt
    37321 tcaaggtgtt actctcgtca gacgcgaata gcctgatgct aaccgagggg aagttcagat
    37381 acaacaaagc cgggaattac ccggctttgt tatggaataa ggcggtgcct aactcgacgt
    37441 ttcgcccgat ggttgatata gctacgctga tatcagaagt tggacggcag gcaccttgtt
    37501 gtgcgtcatt cgtattttat gtagcacgtc ccgaaggggc tgacataagt cggtgaatga
    37561 gccactggtt actattatgc agtaactgtg ccaataaaga aaatagtttg gtaacgtact
    37621 gattatacgt tgctttgagg ggtttatgtc tcctccgctg tttgaatgta aatcagcc
//
LOCUS       DAPHKZ010000037        37601 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.037, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000037 DAPHKZ010000000
VERSION     DAPHKZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37601
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.037"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(27..308)
                     /locus_tag="RH288_001931"
     CDS             complement(27..308)
                     /locus_tag="RH288_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HDV4030986.1"
                     /translation="MNKYWLSGIIFLAYGLASPAFSSETATLAINGRISPPTCSMAMV
                     NGQPQQHCGQLTYNVDTRHLFSSPVKGVTTEVVVAGSDSKRRIVLNRYD"
     gene            complement(571..1680)
                     /gene="apbC"
                     /locus_tag="RH288_001932"
     CDS             complement(571..1680)
                     /gene="apbC"
                     /locus_tag="RH288_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HDV4030987.1"
                     /translation="MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRP
                     ESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV"
     gene            1812..3845
                     /gene="metG"
                     /locus_tag="RH288_001933"
     CDS             1812..3845
                     /gene="metG"
                     /locus_tag="RH288_001933"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDV4030988.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEE
                     NRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSV
                     SFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALAD
                     LANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLN
                     TELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDP
                     IQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"
     gene            3986..7780
                     /locus_tag="RH288_001934"
     CDS             3986..7780
                     /locus_tag="RH288_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR and DUF4132 domain-containing protein"
                     /protein_id="HDV4030989.1"
                     /translation="MRHFIYQDEKSHKFWAVEQQGNELHISWGKVGTKGQSQIKSFSD
                     AAAAAKAELKLIAEKVKKGYVEQAKVNSLQPSQTVTGSLKVADLSTIIQEQPSFVAET
                     RAPDKNTDAVLPWLAKDIAVVFPPEVVHTTLSHRRFPGVPVQQADKLTQLRRLACSVS
                     QRDNKTATFDFSACSLEWQNTVAQAISQIDGLKTTQLPSPVMAVLTALEMKCTRYKVR
                     EDVMDQIVQEGGLEYATDVIIHLQQIDIKWDYANNVIIILPSGIAPDYLEQYSRFELR
                     LRKHLSLAEESLWQKCAQKLIAAIPHIPEWRQPLIALLLPEKPEIAHEIAQRLLGQKK
                     LPSLEWLKIVATDEHILASLEKYHEPYAIFDDYYCGAIWSATVLQEQGVAALPRFAPY
                     AASDYCADVLRHINHPFALTLLIRVAGHTKRCHDRMTKAIAAFPHAAMAALTELLGQK
                     EENSWRIMLMTMLISQPALAEQVIPWLSTPAVAVLKSCQQQLTQPSNHASADLLPAVV
                     VSPPWLSKKKKSPIPVLDLAPLGIEPICYLTEEISNQLLAKYIWYSKHITVSHEESTT
                     NLLARMGFQRRIAGTYIKAPEAVVEAWLNEDYSTLLSEFKVFHSPTGHYWQLGILTTL
                     PLEKAVKAWNALTLSPHTDTEYAMLHFGLKGLPRLVNSLARYPQEALPITNYFAASEL
                     APAVARAFNKLKTLRENARSWLLKYPEHALTGLLPAALGKAGEAQDNARAALRMLTEN
                     GHQPLLQEIARRYNQPEVTDAVNALLALDPLDNHPTKIPTLPAFYQPSLWTRPVLKAN
                     AQSLPDSALLHLGEMLRFPQEEALYPGLLQVKDVCSADSLAGFAWDLFTAWQTAGAPS
                     KESWAFTALGVLGNDDTARKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNG
                     IAQKLKFKALQERAKEKIADIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGPRQFT
                     VSFDETLKPFVRDVSGSRLKDLPKPNKSDDESRSNDAVNRYKLLKKDARTVAAQQVAR
                     LESAMCLRRRWSPENFQLFLVEHPLVRHLTRRLIWGVYSAENQLLACFRVAEDNSYST
                     ADDDLFTLPEGDISIGTPHVLEISPTDAAAFGQLFADYELLPPFRQLDRNSYALTEAE
                     RNASELTRWAGRKCPSGRVMGLANKGWIKGEPQDGGWIGWMIKPLGRWSLIMEIDEGF
                     AVGMSPAELSAEQLLSKLWLWEGKAESYGWGSNSTQEAQFSVLDAITASELINDIEAL
                     VE"
     gene            7790..11422
                     /locus_tag="RH288_001935"
     CDS             7790..11422
                     /locus_tag="RH288_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDV4030990.1"
                     /translation="MDKELPWLADNAQLELKYKKGKTPLSHRKWPGEPVPVITESIIQ
                     TLGDELLQKAEKKKNIVWRYENFSLEWQSAITQAINLIGEHKPSIPARTMAALACIAQ
                     NDSQQLLDEIVQQEGLEYATEVVIARQFIARCYESDPLVVTLQYQDEDYGYGYRSETY
                     NEFDLRLRKHLSLAEESCWQRCADKLIAALPGITKVRRPFIALILPEKPEIANELVGL
                     ECPRTHFHSKEWLKVVANDPTAVRKLEHYWSQDIFSDREASYMSHENHFGYAACAALL
                     REQGLAAIPRLAMYAHKEDCGSLLVQINHPQVIRTLLLVADKNKPSLQRVAKYHKNFP
                     HATLAALAELLALTEPPARPGYPIIEDKKLPAQQKARDEYWRTLLQTLMASQPQLAEE
                     MMQWLSTQARAVLNSYLSAPPKPVIDSTDNSNLPEILVSPPWRSKKKMTAPRLDLAPL
                     ELTPQVYWQPGERERLAATEPARYFSTESLAERMEQKSGRVVLQELGFGDDVWLFLNY
                     ILPGKLDAARNSLIVQWHYYQGRVEEILNGWNSPEAQLAEQALRSGHIEALINIWEND
                     NYSRYRPEKSVWNLYLLAQLPREMALTFWLRINEKKHLFAGEDYFLSILGLDALPGLM
                     LAFSHRPKETFPLILNFGATELALPIARVWHRFAGQRNLARQWILQWPEHTATALIPL
                     IFTKSSDKSEAALLALRLLYEHGHGELLQTVANRWQRTDLWPALEQLLKQSPIEIYPA
                     RIPKAPDFWHPQMWSRPRLITNNQPVTDDALEIIGEMLRFTQGGRFYSGLEQLKTFCQ
                     PQTLAAFAWDLFTAWQQAGAPVKDNWAFLALSLFGDESTARDLTTQILGWPQEGKSAR
                     AVSGLNILTLMNNDMALIQLHHISQRAKSRPLRDNAAEFLQVVAENRGLSQEELADRL
                     VPTLGLDDPQALSFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPRLRADDDQLKAPE
                     ALARLKGLKKDATQVSKNLLPRLETALRTTRRWSLADFHSLFVNHPFTRLVTQRLIWG
                     AYPANEPRCLLNAFRVAAEGEFCNAQDEPIDLPADALIGIAHPLEMTVEMRSEFAQLF
                     ADYEIMPPFRQLARCTVLLTPDESTSNSLTRWEGKSATVGQLMGMRYKGWESGYEDAF
                     VYDLGEYRLVLKFSPGFNHYNVDSKALMSFRSLRVYRDNKSVTFAELDVFDLSEALSA
                     PDVIFH"
     gene            11483..11800
                     /locus_tag="RH288_001936"
     CDS             11483..11800
                     /locus_tag="RH288_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030991.1"
                     /translation="MIVQKELVAIYDYEVPVPEDPFSFRLEIHKCSELFTGSVYRLER
                     FRLHPTFHQRDREDADPLINDALIYIRDECIDERKLRGESPETVIAIFNRELQNIFNQ
                     EIE"
     gene            13040..14128
                     /locus_tag="RH288_001937"
     CDS             13040..14128
                     /locus_tag="RH288_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDV4030992.1"
                     /translation="MSPQNNHLQRPPAAVLYADELAKLKQNDNAPCPPGWQLSLPAAR
                     AFILGDSAQNISRKVVISPSAVERMLVTLATGRGLMLVGEPGTAKSLLSELLATAISG
                     DAGLTIQGGASTTEDQIKYGWNYALLINHGPSTEALVPAPLYQGMRDGKIVRFEEITR
                     TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKR
                     RFDFETVFPIMDFAQELELVASASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEK
                     KTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVDCIAGTIVKDNEEDRAR
                     LRRYFEQRVATHKEAHWQAYYQARHRLP"
     gene            14139..16418
                     /locus_tag="RH288_001938"
     CDS             14139..16418
                     /locus_tag="RH288_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708008.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4030993.1"
                     /translation="MSEPLIVGIRHHSPACARLVKSLIESQRPRYVLIEGPADFNDRV
                     DELFLAHQLPVAIYSYCQYQDGAAPGRGAWTPFAEFSPEWQALQAARRIQAQTYFIDL
                     PCWAQSEEVDDSPDTQEESQALLLRATRMDNSDTLWDHLFEDESQQTALPSALAHYFA
                     QLRGDSPGDALNRLREAFMARWIGWAMQQNNGDVLVVCGGWHAPVLAKMWRECPQEIN
                     TPELPSLADAVTGCYLTPYSEKRLDVLAGYLSGMPAPVWQNWCWQWGLQQAGEQLLKT
                     VLTRLRQHKLPASTADMAAAHLHAMALAQLRGHTLPLRTDWLDAIAGSLIKEALNAPL
                     PWSYRGVIHPDTDPILLTLIDTLAGDGFGKLAPSTPQPPLPKDVTCELERTAISLPAE
                     LTLNRFNPNGLAQSQVLHRLAILEIPGIVRQQGSTLTLAGNGEERWKLTRPLSQHAAL
                     IEAACFGATLQEAARHKLEADMLDAGGIGSITTCLSQAALAGLASFSQQLLEQLTLLI
                     AQENQFAEMGQALEVLYALWRLDEISGMQGAQILQTTLCAAIDRTLWLCESNGRPDEK
                     EFHAHLHSWQALCHILRDLHSGVQLPGISLSAAVALLERRSQAIHAPALDRGAAHGAL
                     MRLEHPNASAEAALTMLAQLSPAQSGEALHGLLALARHQLACQPTFIAGFSSHLNQLS
                     DADFINALPDLRAAMAWLPPRERGTLAHQVLEHYQLAQLPVSALQMPLHCPPQAIAHH
                     QQLEQQALASLQNWGVFHV"
     gene            16411..17547
                     /locus_tag="RH288_001939"
     CDS             16411..17547
                     /locus_tag="RH288_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDV4030994.1"
                     /translation="MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEW
                     LYGRDPERLQRGERSGGLGGSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVV
                     TNLDVLERMQPSESLLRAVLHTKHLMNPEVLAAARQIVRQVVEEIMARLAKEVRQAFS
                     GVRDRRRRSLIPLARNFDFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRQSEQWQLV
                     LLVDQSGSMVDSVIHSAVMAACLWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQ
                     LGGGTNIASAVEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQVKKCVQSGIKVLGL
                     AALDSTATPCYDRDTAQALVNVGAQIAAMTPGELASWLAENLQS"
     gene            17544..19544
                     /locus_tag="RH288_001940"
     CDS             17544..19544
                     /locus_tag="RH288_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HDV4030995.1"
                     /translation="MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHEN
                     GALIATFSDGVRTQLANSQALKEAQCSCGASGMCRHRVMLVLSYQRLCATVQPTEKEE
                     EWDPAIWLEELATLPDATRKRAQALVAKGITIELFCAPGEIPSARLPMSDVRFYSRSS
                     IRFARCDCIEGTLCEHVVLAVQAFVEAKAQQAEFNHLIWQMRSEHVTSSDDPFASEEG
                     QTCRQYVQQLSQALWLGGISQPLIHYEAAFNRALQAAEACNWRWVSESLRQLRASVDA
                     FHTRASHYHAGECLRQLAALNSRLNCAQEMARRDSVGEVPPVPWRTVVGSGIAGEAKL
                     DHLRLVSLGMRCWQDIEHYGLRIWFTDPDTGSILHLSRSWPRSEQENSPAATRRLFSF
                     QAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVALR
                     EYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNLLTLSL
                     PASACSPFAVERMAALLQQTDDPVSLVSGFVSFVDGQLTLEPRVMMTKTRAWALDAET
                     APVAPLPSASVLPVPSTAHQLLMRCQALLIQLLHNGWRYQEQSAISQAELLANDLSAV
                     GFYRLAHVLGQFRNTESEARVEAMNNGVLLCEQLFPMLQQQG"
     gene            19669..20130
                     /locus_tag="RH288_001941"
     CDS             19669..20130
                     /locus_tag="RH288_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HDV4030996.1"
                     /translation="MKAFNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAIT
                     YVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKLTYTDTYA
                     QENVTIDMEKVDFKALQGISGINVSAEDAKKGITMAQMELVMKAAGFKEVK"
     gene            complement(20171..20641)
                     /locus_tag="RH288_001942"
     CDS             complement(20171..20641)
                     /locus_tag="RH288_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HDV4030997.1"
                     /translation="MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKE
                     DEEGFQRCPDIVLSSFLNGLIYEKRGKDESAPALEPERRINNNIVLKKLRIAFSLKTD
                     DILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKS"
     gene            complement(20688..21407)
                     /gene="yehT"
                     /locus_tag="RH288_001943"
     CDS             complement(20688..21407)
                     /gene="yehT"
                     /locus_tag="RH288_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310963.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HDV4030998.1"
                     /translation="MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVH
                     KLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IDEARLEKTLARLRQERSKQDVSLLPENQQVLKFIPCTGHSRIYLLQMKDVAFVSSRM
                     SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            complement(21404..23089)
                     /gene="btsS"
                     /locus_tag="RH288_001944"
     CDS             complement(21404..23089)
                     /gene="btsS"
                     /locus_tag="RH288_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system sensor histidine
                     kinase BtsS"
                     /protein_id="HDV4030999.1"
                     /translation="MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKF
                     LCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILA
                     IARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISST
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQV
                     NIAIPQELSQQQLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNA
                     GLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLPWRDEA"
     gene            23311..24042
                     /gene="mlrA"
                     /locus_tag="RH288_001945"
     CDS             23311..24042
                     /gene="mlrA"
                     /locus_tag="RH288_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HDV4031000.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRT
                     WIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKK
                     QGKDALVVGWNIQDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFEGRTLLVWCGE
                     NRTSAQQQQLTSWQEQGHDIFPLGI"
     gene            24102..24209
                     /locus_tag="RH288_001946"
     CDS             24102..24209
                     /locus_tag="RH288_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HDV4031001.1"
                     /translation="MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG"
     gene            complement(24190..24921)
                     /gene="yehW"
                     /locus_tag="RH288_001947"
     CDS             complement(24190..24921)
                     /gene="yehW"
                     /locus_tag="RH288_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehW"
                     /protein_id="HDV4031002.1"
                     /translation="MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPSVAV
                     LAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
                     KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIADRLFERLVQALSQHAK"
     gene            complement(24926..25852)
                     /gene="yehX"
                     /locus_tag="RH288_001948"
     CDS             complement(24926..25852)
                     /gene="yehX"
                     /locus_tag="RH288_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter ATP binding
                     protein YehX"
                     /protein_id="HDV4031003.1"
                     /translation="MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGEIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWSVAQNIATVPQL
                     QKWSRARIDDRIDELMALLGLESNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGN
                     PLTMLTRPANDFVRQFFGRSELGVRLLSLRSVADYVRREERADGEALAEEMTLRDALS
                     LFVARGCEVLPVVNMQGQPCGTLHFQDLLVEA"
     gene            complement(25845..27002)
                     /gene="yehY"
                     /locus_tag="RH288_001949"
     CDS             complement(25845..27002)
                     /gene="yehY"
                     /locus_tag="RH288_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehY"
                     /protein_id="HDV4031004.1"
                     /translation="MTYFRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQL
                     WPQTIWMLVGVGCAWLTACFIPGKKGSICALILAQFVFVLLVWGAGKAATQLAQNGSA
                     LARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
                     SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNV
                     IQTVPSVALFGLLIAPLAALVTAFPWLGTLGIAGTGMTPALIALVLYALLPLVRGVVV
                     GLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIG
                     AGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKRND"
     gene            complement(27009..27926)
                     /gene="osmF"
                     /locus_tag="RH288_001950"
     CDS             complement(27009..27926)
                     /gene="osmF"
                     /locus_tag="RH288_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein OsmF"
                     /protein_id="HDV4031005.1"
                     /translation="MPLLKLWAGSLVMLAAVSLPLQAASPVKVGSKIDTEGALLGNII
                     LQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDAAWKNAQ
                     QGYEKVKKLDSEHNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTF
                     KLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLREYPQMAQWLQPVFASLDAKTL
                     QQLNASIAVEGLDAKKVAADYLKQKGWTK"
     gene            complement(28137..30434)
                     /gene="bglX"
                     /locus_tag="RH288_001951"
     CDS             complement(28137..30434)
                     /gene="bglX"
                     /locus_tag="RH288_001951"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HDV4031006.1"
                     /translation="MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRL
                     KIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSTMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     QWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKS
                     GKVTMAELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAV
                     GENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAV
                     VGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKP
                     NKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKRE
                     GATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGTDSARVKKGEFELL"
     gene            30630..32345
                     /gene="dld"
                     /locus_tag="RH288_001952"
     CDS             30630..32345
                     /gene="dld"
                     /locus_tag="RH288_001952"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDV4031007.1"
                     /translation="MSSMTTTDNKAFLNELARLVGSSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDVVIISTL
                     RLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRH
                     DGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQ
                     QVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGT
                     DKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSD
                     EVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVDVH
                     ALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKN
                     WQEVE"
     gene            complement(32383..33315)
                     /gene="pbpG"
                     /locus_tag="RH288_001953"
     CDS             complement(32383..33315)
                     /gene="pbpG"
                     /locus_tag="RH288_001953"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416638.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HDV4031008.1"
                     /translation="MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAM
                     IVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVY
                     SRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTR
                     FVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNH
                     LVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTW
                     IETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND"
     gene            complement(33489..34076)
                     /locus_tag="RH288_001954"
     CDS             complement(33489..34076)
                     /locus_tag="RH288_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HDV4031009.1"
                     /translation="MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICA
                     FIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
                     EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF"
     gene            34246..34824
                     /locus_tag="RH288_001955"
     CDS             34246..34824
                     /locus_tag="RH288_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV4031010.1"
                     /translation="MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLV
                     VLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFM
                     YGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHL
                     KHWVWLILVVVLVVGVRWWLKRRGKKKPDHQA"
     gene            complement(34954..35715)
                     /locus_tag="RH288_001956"
     CDS             complement(34954..35715)
                     /locus_tag="RH288_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV4031011.1"
                     /translation="MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTA
                     REVVSHGVRAEIVQLDLGNLPEGALALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFD
                     EWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
                     GGLTKAMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIA
                     SLVVWLCSEGANYTTGQSLIVDGGFMLANPQFNPE"
     gene            complement(35768..37204)
                     /gene="mdtQ"
                     /locus_tag="RH288_001957"
     CDS             complement(35768..37204)
                     /gene="mdtQ"
                     /locus_tag="RH288_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001583680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HDV4031012.1"
                     /translation="MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTA
                     LPKALKNGWPDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAVATQD
                     GPQIDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNR
                     AEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIAT
                     DRQLYQNGITSSVEGVETDINASKTRQQLNDVAGKMKIIEARLSALTNNQTKSLKLKP
                     VALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAESNLSIASYNKAVVEAV
                     NDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRE
                     RANGLLLQGQWLDASIQLTGALGGGYKR"
     gene            37428..37511
                     /gene="yohP"
                     /locus_tag="RH288_001958"
     CDS             37428..37511
                     /gene="yohP"
                     /locus_tag="RH288_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HDV4031013.1"
                     /translation="MKIILWAVLIIFLIGLLVVTGVFKMIF"
BASE COUNT         9311 a        10009 c         9434 g         8847 t
ORIGIN      
        1 aatgcaatta aaatcaggtt gccaaattaa tcgtagcgat ttaacacgat tcgacgtttg
       61 ctatcgctac ctgcaacaac cacttctgtc gttacacctt tgacgggcga agaaaacaga
      121 tgacgggtgt caacattata cgttaactga ccacaatgct gttgaggttg accattaacc
      181 atagccatac tgcatgttgg gggactgatc ctgccattaa tcgctaatgt ggcagtctct
      241 gaagagaacg cgggagaagc caatccatag gcaagaaaaa taattcctga cagccaatac
      301 ttattcattg aacgttatcc ctgtagtaaa ggttatgcct ggatagaatg agtgcataac
      361 aaactatagc tgtacatcca ctacacagcc acgaaggatg ataatgaagc attgcctgta
      421 cggtcaatcg actttgtaga gtttcggacg aaggtccgca gaatattcgc agtattaaat
      481 aagtgttcat taatgcggca aaaacaaata caccgcatca atataacatc tctgcggtgt
      541 atgaagaata accagaatgg ttaataggcg ttagaccgcg cggaaggaaa tctcgcctgg
      601 aatgacttca ccctgccagt agagctgagc tgcaacgcgg tcagccagct ggcggtagat
      661 agcggtaaat tcgctctccg gacggctgat aaccgttggc gtgcctttat cgagatcctc
      721 acgtaaggag atgtgtaacg gcatctgccc cagcagctgt gtgtggtatt tttcagccag
      781 tttctcagca ccaccggtac cgaaaatcgg ttcatggtga ccacagttac tgcaaatatg
      841 cacactcatg ttctcgacaa taccaagcac cggaacctcg actttctcga acatcacaat
      901 gccttttttc gcatcgatca acgcgatgtc ctgcggggtg gtgaccacga ctgcaccagt
      961 tactggaatg ttttgcgcca gcgtcaattg aatgtcaccg gtgcctggcg gcatatcaag
     1021 caccagatag tcgagatccg gccacaaggt ttcctgcaac atctgcatta acgccttgct
     1081 cgccatcggt ccacgccaca ccatcgcatt gtcgtcagtg accagataac caattgaatt
     1141 ggttgccagg ccatgagaca taatcggtgc catatgggta ccgtccggcg aagttggacg
     1201 ctgattttct gcgcccagca tggtgggaat tgatgggccg tagatatcgg cgtccagaat
     1261 gccgactttc gccccttccg ccgccagtgc cagcgccagg tttaccgccg tggaggattt
     1321 acccacgccg cctttaccgg aactgaccgc aatgatgttc ttcacaccat taatacccgg
     1381 ctgattcttc acgcgtttta aggtggcgat attgtgcgac agtttccagt cgatagcttt
     1441 cgccccggtg atacgcagca gttcggcgct acattgctct tttaactctt caaacgcgct
     1501 atgccagacg aatggcataa ccagttccac atgcaacgtg tcgtccatcc aggcgacatg
     1561 gtgcaacgct ttcagcgtgg tgaggttatg cttcagggtt gggtgctgaa aattggccag
     1621 tgtcccggcg accattgcgc gcaaggcttc tggtgatttg gcctgggatt gttcgttcat
     1681 cccgactcct tttttgtata aataaaccat cagctgatag tttacctgaa gaatatagag
     1741 aagtacttac ttaacatttt cccatttggt actatctaac cccttttcac tattaagaag
     1801 taatgcctac tatgactcaa gtcgcgaaga aaattctggt gacgtgcgca ctgccgtacg
     1861 ctaacggctc aatccacctc ggccatatgc tggagcacat ccaggctgat gtctgggtcc
     1921 gttaccagcg aatgcgcggc cacgaggtca acttcatctg cgccgacgat gcccacggta
     1981 caccgatcat gctgaaagct cagcagcttg gtatcacccc ggagcagatg attggcgaaa
     2041 tgagtcagga gcatcagact gatttcgcag gctttaacat cagctatgac aactatcact
     2101 cgacgcacag cgaagagaac cgccagttgt cagaacttat ctactctcgc ctgaaagaaa
     2161 acggttttat taaaaaccgc accatctctc agctgtacga tccggaaaaa ggcatgttcc
     2221 tgccggaccg ttttgtgaaa ggcacctgcc cgaaatgtaa atccccggat caatacggcg
     2281 ataactgcga agtctgcggc gcgacctaca gcccgactga attgatcgag ccgaaatcgg
     2341 tggtttctgg cgctacgccg gtaatgcgtg attctgaaca cttcttcttt gatctgccct
     2401 ctttcagcga aatgttgcag gcatggaccc gcagcggtgc gttgcaggag caggtggcaa
     2461 ataaaatgca ggagtggttt gaatccggcc tgcaacagtg ggatatctcc cgcgacgcgc
     2521 catactttgg ttttgaaatt ccgaacgcgc cgggcaaata tttctacgtc tggctggacg
     2581 caccgattgg ctacatgggt tctttcaaga atctgtgcga caagcgcggc gacagcgtaa
     2641 gcttcgatga atactggaag aaagactcca ccgccgagct gtaccacttc atcggtaaag
     2701 atattgttta cttccacagc ctgttctggc ctgccatgct ggaaggcagc aacttccgca
     2761 agccgaccaa cctgtttgtt catggctatg tgacggtgaa cggcgcaaag atgtccaagt
     2821 ctcgcggcac ctttattaaa gccagcacct ggctgaatca ttttgacgct gacagcctgc
     2881 gttactacta cactgcgaaa ctctcttcgc gcattgatga tatcgatctc aacctggagg
     2941 atttcgttca gcgtgtgaat gccgatatcg tgaacaaagt ggttaacctg gcctctcgta
     3001 atgcgggctt tatcaacaag cgttttgacg gcgtgctggc aagcgaattg gctgacccgc
     3061 agttgtacaa aaccttcact gatgccgctg aagtgattgg tgaagcgtgg gaaagccgcg
     3121 aatttggtaa agcagtgcgc gaaatcatgg cgctggctga tctggctaac cgctatgtcg
     3181 acgagcaggc tccgtgggtg gtggcaaaac aggaaggccg cgatgccgac ctgcaggcaa
     3241 tttgctcaat gggcataaac ctgttccgcg tgctgatgac ttacctgaag ccggtactgc
     3301 cgaaactgac cgagcgcgca gaagcattcc tcaatacaga actgacctgg gatggtatcc
     3361 agcaaccgct gctgggccac aaagtgaatc cgttcaaagc gctgtataac cgcatcgata
     3421 tgaagcaggt tgaagcactg gtggaagcgt ctaaagaaga agtgaaagca gctgccgcgc
     3481 cagttactgg cccactggca gatgatccga ttcaggaaac catcaccttt gacgacttcg
     3541 caaaagttga cctgcgcgtt gcgctgatcg aaaacgcaga gtttgttgaa ggttctgaca
     3601 aactgctgcg cctgacactg gatctcggcg gtgaaaaacg caatgtcttc tccggtattc
     3661 gttctgccta cccggatccg caggcactga tcgggcgtca caccattatg gtggccaacc
     3721 tggcaccgcg taaaatgcgc tttggtatct ccgaaggcat ggtaatggct gctggtcctg
     3781 gcgggaaaga tatcttcctg ttaagcccgg atgctggtgc taaaccaggc catcaggtga
     3841 aataatcccc ctttaaggcg ctgcatcgac agcgcctttt ctttataaat tcctaaagtt
     3901 gttttcttgc gattttgtct ctctctaacc cgcataaata ctggtagcat ctgcattcaa
     3961 ctggataaaa tcacagggat gcagaatgag acactttatc tatcaggacg aaaaatcaca
     4021 taaattctgg gcagttgagc aacagggaaa cgagttgcat atcagttggg gaaaagttgg
     4081 caccaaaggg caaagccaga taaaaagttt ttcagatgct gcggcagcgg caaaagcgga
     4141 gcttaagctg attgcggaga aggtgaagaa ggggtatgtg gagcaagcga aggttaattc
     4201 tttgcaacct tcccaaacgg taacgggctc tctcaaggta gcggacttat ccaccattat
     4261 tcaggaacaa ccctctttcg tagcagaaac ccgtgcgcct gacaaaaata cagatgctgt
     4321 tttaccgtgg ctggcgaaag atattgctgt cgtttttccg cccgaagttg tacacaccac
     4381 gttaagtcat cgccgctttc ccggagttcc tgttcagcaa gcagacaaat tgacccaatt
     4441 acgtcgctta gcctgtagtg tgtcgcaacg ggataataaa acagccacat ttgacttcag
     4501 cgcctgttct ttagaatggc aaaacaccgt cgcccaggcg atcagtcaga tcgacggcct
     4561 gaaaacaaca cagctaccat caccagtaat ggctgtactc acggcacttg aaatgaaatg
     4621 cacaagatat aaagtgcgtg aggatgttat ggatcagatc gtccaggaag gcggtctgga
     4681 atatgctact gatgtaataa tacaccttca acagattgat attaaatggg attatgcgaa
     4741 taatgtcatt attattctac cgtctggcat tgcacctgac tacttggagc aatattccag
     4801 atttgaatta cgcctacgta aacatttatc actggcggaa gagtctctct ggcaaaaatg
     4861 tgcacaaaaa cttattgccg caattccaca tattccagaa tggcggcaac cattaattgc
     4921 tttgttatta cccgaaaaac cagaaattgc acatgaaatt gcccagcgtc tactggggca
     4981 aaaaaaatta ccctcgcttg agtggttaaa aatagtggcg actgatgagc acattcttgc
     5041 ctcattagaa aaatatcacg agccatatgc catttttgat gattactatt gtggtgcgat
     5101 atggtcagcc accgtattac aggagcaagg tgttgcagcc ctgccccgat ttgctcccta
     5161 tgccgcaagt gactactgcg ccgatgtgtt gcgtcatatc aatcatccgt tcgcattaac
     5221 actgcttata cgtgtagccg ggcatactaa acgctgtcac gatcggatga cgaaagccat
     5281 tgctgcgttc ccacatgcag caatggcggc actgacggaa cttcttgggc aaaaagaaga
     5341 gaacagttgg cgcattatgc taatgacaat gcttatctca caaccagcac tggcagaaca
     5401 ggtcattccc tggctctcga cacccgcagt tgccgtactg aaatcatgcc agcaacaact
     5461 gacacagccc tcaaaccatg ccagcgccga tctactgcca gccgtagtag tctcccctcc
     5521 ctggctttcg aaaaagaaaa aatcgccgat tccggtgctg gatttagcgc cattaggcat
     5581 tgagccaatc tgttatctga cagaagaaat cagtaatcaa cttttggcga aatatatctg
     5641 gtattcaaaa cacatcacgg ttagccatga agaaagtact accaacctgt tggcaaggat
     5701 gggttttcaa cgacggatcg ctggtacata tattaaagct cccgaagcgg tagttgaggc
     5761 atggctaaat gaagattatt caaccttact aagtgaattt aaggtgtttc attcacctac
     5821 cgggcattat tggcagttgg ggattttgac aacattgccg ctggagaaag cagtaaaagc
     5881 atggaatgcc cttaccctat ctccacatac cgataccgaa tacgccatgt tacattttgg
     5941 actcaaaggg ttacctaggt tagtaaactc acttgcacgc tatccacaag aagccttgcc
     6001 catcacgaat tacttcgcag cgagtgagct ggctcctgcc gtcgcccgtg ccttcaacaa
     6061 actgaaaacg ctacgcgaaa acgcccgtag ctggctgttg aaatacccgg aacatgccct
     6121 taccggcctg ctgcctgcgg cgctcggcaa agccggtgaa gcacaggata acgcccgcgc
     6181 tgccttgcgt atgcttaccg aaaacggtca tcagccatta ctgcaagaaa tcgcccgacg
     6241 ttataaccag ccggaagtaa ccgatgcggt gaacgctctg cttgcgctcg atcccttaga
     6301 taatcacccg acaaaaatcc ccactcttcc ggccttttat cagccatcgc tctggacgcg
     6361 cccggtatta aaagcaaatg cccaatcact gccagatagc gccctcctcc acctcggtga
     6421 aatgctccgc ttccctcagg aagaggctct gtatccggga ttattgcagg tgaaagacgt
     6481 ctgttccgcc gactcactgg cgggatttgc ctgggatctg tttaccgcct ggcagaccgc
     6541 tggcgcgccg tcgaaagaga gttgggcgtt cactgcgtta ggcgttctcg gtaacgatga
     6601 caccgcccgc aaactgacgc cattaatacg cgcctggcct ggtgaatccc agcataaacg
     6661 cgccaccgtt gggttggata ttctcgctgc tatcggtagt gatatcgccc ttatgcagct
     6721 taacggcatc gcccagaaac tgaaattcaa agcattacag gagcgggcaa aagaaaaaat
     6781 tgccgacatt gccgagagcc gcgaactcac ggtggcggag cttgaagatc ggttagcacc
     6841 ggatctcggt ctggatgata acggttcgct gctgctggat tttggcccac ggcagttcac
     6901 cgtcagcttt gatgaaacct taaaaccgtt tgtgcgtgat gtttccggca gccgcctgaa
     6961 agacctgccc aaaccgaaca aaagcgatga tgaatcgcgg tcgaacgatg cggttaaccg
     7021 ctacaaattg ctgaaaaaag atgcgcgtac cgtcgccgcc cagcaggtag caaggctgga
     7081 atccgccatg tgcctgcgcc gccgctggtc gccggaaaac ttccagctct tcctggttga
     7141 gcatccgctg gttcgccact taacccgccg tctgatttgg ggcgtttata gcgccgaaaa
     7201 ccagctactg gcttgctttc gcgtagcaga agataacagc tacagcaccg ctgacgatga
     7261 tcttttcacc ctgccggaag gcgatatctc tatcggcact cctcacgttc tggaaatatc
     7321 accaacggat gctgccgcct ttggtcagct ttttgccgac tacgaactgc taccaccgtt
     7381 ccgccagctc gaccgtaaca gctacgccct gacagaagcc gagcgcaatg ccagtgaact
     7441 gacccgctgg gcaggcagaa aatgcccgag tggtcgggtc atggggctgg cgaataaagg
     7501 ctggataaag ggcgaaccac aggatggagg ctggatcgga tggatgatca aacctttggg
     7561 tcgctggtcg ttaatcatgg aaatcgacga aggttttgcg gtgggtatgt caccagccga
     7621 acttagcgct gagcagctct taagcaagct gtggttatgg gaaggcaaag cggaaagcta
     7681 tggctggggg agtaattcaa cacaggaagc gcagttctcc gtactcgatg ccatcaccgc
     7741 cagcgagcta attaacgata ttgaagccct ggttgaataa ggaaagagca tggacaagga
     7801 attaccgtgg ctggcggata acgcccaact ggaactgaaa tataaaaaag gcaaaacacc
     7861 actcagtcat cgcaaatggc cgggcgaacc ggtgcctgtt atcactgaaa gcatcattca
     7921 gacactgggt gatgaattgc tacaaaaagc tgagaagaaa aaaaacattg tctggcgtta
     7981 tgaaaatttt tcactggagt ggcagtccgc catcacgcag gccatcaact tgatcggcga
     8041 acacaaaccc tcaatcccgg cccggacaat ggcggcgcta gcctgtatcg cgcaaaatga
     8101 cagccaacag ttgctcgacg aaatcgtcca acaagagggg ctggaatatg cgactgaggt
     8161 ggtgattgca cgccagttta ttgcgcggtg ttatgagagt gatcctctgg tagtgacatt
     8221 gcagtatcag gacgaggatt atggctatgg ttatcgctca gaaacctata acgaattcga
     8281 tctccgactg cgtaagcatc tctctctggc agaggaaagc tgctggcagc gttgcgccga
     8341 caaactcatt gccgcactac caggaataac caaagttcgc cgccctttta ttgcgctgat
     8401 cctcccggaa aaaccagaaa tagccaatga gttggtaggc cttgaatgcc cgcgaactca
     8461 ttttcattct aaggagtggt taaaagttgt tgctaatgac cccacagcgg tgagaaaact
     8521 cgagcactac tggagccagg atatatttag cgatcgagaa gccagctaca tgtcgcatga
     8581 aaaccacttc ggctacgcgg cctgcgccgc ccttttgcgc gaacaaggac tggcagccat
     8641 tccgcgcctc gcgatgtatg cccataaaga agattgcggc agtctgctgg tacaaattaa
     8701 ccatccgcaa gtcatccgca ccttgctact ggtggctgat aaaaacaaac ccagcctgca
     8761 acgtgtagct aaataccata aaaacttccc ccatgcgacg ctcgccgcac tggcagaact
     8821 gctggcgtta acagaaccac cagcccgccc aggttatcca atcatcgaag acaaaaagct
     8881 gcctgcacag caaaaagcac gcgatgaata ctggcgtacg ctgttacaaa cgctgatggc
     8941 atcgcagcca caactggcag aagagatgat gcagtggtta agtactcaag ccagggcagt
     9001 gctgaatagt tatttatcgg caccgcccaa accggttatt gatagtaccg ataacagcaa
     9061 tctgcctgaa atcctcgttt caccaccgtg gcgtagtaag aaaaaaatga cagctccacg
     9121 tcttgatttg gcaccgctcg aattaacgcc gcaagtttac tggcaacctg gcgaacgaga
     9181 gaggcttgcc gccactgagc ctgcccgtta tttcagcacg gaatctcttg cggaacgcat
     9241 ggaacaaaaa agtgggcgag ttgtattaca ggaactgggt tttggggatg atgtatggct
     9301 gtttttgaat tatatactcc ccggaaaact ggatgctgca cgcaattcac tcattgttca
     9361 gtggcattac taccaggggc gggttgaaga gatcctgaat ggctggaact ccccggaagc
     9421 acaattagca gaacaggcgc tccgcagcgg tcacatagaa gcgttaatta acatatggga
     9481 aaatgacaac tactcacgtt atcgtccgga aaagagtgtc tggaacctgt atttattggc
     9541 acagttgccg cgtgagatgg ctttgacctt ctggctgcgt atcaatgaga aaaaacatct
     9601 gttcgcgggt gaggactatt ttctcagtat cctcgggttg gatgcgctac caggtctgat
     9661 gttggctttt tcacatcgtc caaaagaaac atttccgtta attttaaatt tcggcgcaac
     9721 agaactggcc ctgcccattg cccgcgtctg gcaccgtttt gcgggccagc gtaatctggc
     9781 tcgccagtgg attttacaat ggccggaaca tacggctact gcacttatcc ctcttatctt
     9841 caccaaatct agcgataaaa gcgaagctgc attacttgcc ctgcgtttac tttacgaaca
     9901 tgggcatggc gaattgctac aaactgtagc caatcgttgg cagcgtacag atctatggcc
     9961 tgccctggaa caattactta aacagagtcc aatagagatt tacccggcac gcattccaaa
    10021 agcccctgat ttctggcatc cgcaaatgtg gtccaggccg cgccttatca ctaataatca
    10081 acctgttacc gatgacgctc tggaaattat cggcgaaatg ctgcgcttta cccagggggg
    10141 acgtttttat agcgggctgg aacaactgaa aacgttctgc cagccacaaa cgctggcagc
    10201 ttttgcctgg gatctcttca ctgcgtggca acaagctggt gcccccgtaa aagacaactg
    10261 ggcatttctg gcgttaagtc tctttggtga cgaaagcacg gcacgggatc taacgacaca
    10321 gatcctcggc tggccacaag aaggcaaatc tgcccgtgct gtcagtggcc tgaacatcct
    10381 taccctgatg aataatgata tggcgctgat acagctgcat catatatcgc aacgggcgaa
    10441 atcccgcccc ttacgtgata acgcggcgga atttcttcag gtggtcgcag aaaatcgcgg
    10501 gctaagccag gaagagctag cggacagatt agtcccaacc ctgggccttg atgatccgca
    10561 ggcgttgagt tttgattttg gtccccggca gtttaccgtt cgcttcgatg aaaacctcaa
    10621 cccggttatc tttgatcagc aaaacgttcg ccagaaaagc gttccccggt tgcgcgccga
    10681 tgacgatcaa ctgaaagcgc ccgaggcact ggcccgacta aaagggctaa aaaaagatgc
    10741 cactcaggtg agcaaaaacc tgctcccgcg tcttgaaacg gccctacgta ccacccgacg
    10801 ctggtcgctg gcagattttc attctctgtt tgttaatcat ccctttaccc gtctggttac
    10861 ccagcgatta atatgggggg cttatccggc aaatgaaccg cgttgtttac tcaacgcctt
    10921 tcgtgtggcc gcagaggggg agttctgcaa tgcgcaagat gagccaattg acctgcctgc
    10981 ggacgctctg attggcattg cccacccgtt agaaatgaca gtagaaatgc gcagtgaatt
    11041 tgcacagctt tttgccgatt acgaaattat gccgcctttt cgccagttgg cgcggtgcac
    11101 ggtgctgctc acacctgatg agtcaaccag taacagcctg actcgctggg aaggtaaatc
    11161 cgctaccgtt gggcagctta tgggaatgcg atacaaaggc tgggagtcag gctatgagga
    11221 tgcatttgtc tatgacctgg gcgagtaccg gctggtcctt aagttttcac ccggttttaa
    11281 ccactacaat gttgatagca aagcgctaat gagcttccgt tctcttcgag tgtaccgtga
    11341 caataaatcc gtcacttttg ccgaacttga tgtgtttgat ttgagtgagg cgttaagcgc
    11401 acctgacgtc attttccatt aaaacacagc gggcagtgat gcgactgccc gttatctaca
    11461 cgacttacca gcggggaaag cgatgatcgt gcaaaaagag ctagttgcta tttacgatta
    11521 tgaggtccct gtacctgaag atccgttttc cttcagactt gagatccata aatgctctga
    11581 attatttaca ggttccgtct atcgactgga gcgattccgg ctacatccaa catttcatca
    11641 acgtgatcga gaagatgctg acccgctaat aaatgatgcg ttgatttata taagagatga
    11701 gtgtattgat gagcggaaat tacgaggtga atcacctgaa actgtaatag caatttttaa
    11761 tcgtgaacta cagaatatat tcaaccaaga aatagaataa tatactctag ataattaaag
    11821 tcgcagcaca tgcaacttga agtatgacga gtatagcttt cttaaagggg gaaacggtat
    11881 tcccccttag atgcgtttca atttgcccgt tacttcaaca aatcaatcaa ccgtaacaga
    11941 gccactaata actccagtac ggcaatgagc acggttaact tttgtgtcag cgtgtccatc
    12001 cgctctcctt attaaggagc gcaacaccag caccttaccc ttacactgcc tgttgatact
    12061 ggtttacgta tgttggtacg aaacgttgct ctccggatca gggcaccgcc tgcggcacca
    12121 cccgtccggc agccaggact taaaattggt ccgatccggc acaacctccc aacgggcagg
    12181 attataaatc tcactcactg aattgcaatg gagtgtggat atggttataa tttattcgtt
    12241 ggtacgaaat gttgcacaat cagcaagtta gcgtcactgt agtaaataaa agaacctgcc
    12301 tcaccagcag gtttttttat tttctgcgat ctactttcca gatatttttt gccaatagcc
    12361 caacataaat attcacatcc cggtcaaatg gtgcgttgaa tataaaatcg atgaatttat
    12421 aaataaaaat gagttatatg atgaattaat aaaaacagta atcattttat taaaggggga
    12481 agcggttttc ccccttagat gcgtttcaat ttgcccgtta cttcaacaaa tcaatcaacc
    12541 gtaacagagc cactaatagc tccagtacag caatgagcac ggttaacttt tgtgtcagcg
    12601 agtccatccg ctctccttat taaggagcgc aacaccagca ccttaccctt acactgcctg
    12661 tcgatactgg tttacgtatg ttggaccacg atgttgcact ccggatcagg gcaccacctg
    12721 cagcaccccc cgtccggtag ccaggacttg aaataggttc gatccggcgc aacgtcccaa
    12781 cggtctggat tataaatctc attatcttaa ttgcaacggg gtccagccgt ggttataatt
    12841 cgttcgttgg aacacgatgt tgcacaggct gtggtgttag gcctgaaaat agtaaataaa
    12901 agaacctgcc tcaccagcag gtttttttat ttactgcgat ctgctttcca gatatttttt
    12961 gctcaaacaa ctaatgcgcc aaacatttat tgcgcgtaaa atatcgttta tttcattaat
    13021 acatttcagg gatgaatata tgtcaccgca gaataatcat ctgcagcgtc cgcctgctgc
    13081 tgtgttatac gccgatgaac tggcaaaatt aaaacaaaat gataacgctc cttgcccgcc
    13141 cggttggcag ttaagtttgc ctgcggcccg tgcttttatc cttggcgata gcgcgcaaaa
    13201 tattagccgt aaagtggtga ttagtccctc cgctgtcgaa cgtatgttag tcactcttgc
    13261 caccggacgc ggtttgatgt tggtggggga acctggcacc gcaaaatctc tcctgtctga
    13321 attactggca accgctatta gcggcgatgc cgggttaacc atccagggcg gcgcatctac
    13381 cactgaagat caaatcaagt acggctggaa ctacgctctg cttatcaatc atggcccatc
    13441 aacggaagcg ctggtccctg ccccgcttta ccagggaatg cgcgacggca aaatcgtccg
    13501 ttttgaagag ataacgcgta caccgctgga agtgcaagac tgtctgttag gtatgctttc
    13561 tgacagggtg atgacggtgc cggaactcac tggtgaagcc agtcagctct atgcgcgaga
    13621 aggctttaat attattgcca ctgccaatac ccgagatcgc ggcgtcaatg aaatgagtgc
    13681 tgcgctaaag cgtcgcttcg attttgaaac tgtctttccg attatggatt tcgcccagga
    13741 gctggagctt gtcgccagtg cttcggcgcg tttgctggcc catagcggta ttccgcataa
    13801 agtgcctgac gcggtactgg agttactggt ccgcaccttc cgcgatctgc gtgccaacgg
    13861 cgaaaagaaa acgtcaatgg atacactaac agcgattatg tccaccgctg aagccgtgaa
    13921 cgtggcccac gccgtaggcg tccgcgcctg gtttttagcg aatcgcgcag gtgagccagc
    13981 cgacctggtg gactgcattg ccggaaccat cgtcaaagat aacgaagaag atcgcgctcg
    14041 tctgcgccgt tacttcgaac aacgagtcgc cacacataaa gaagctcact ggcaggctta
    14101 ttatcaagcc cgccaccgcc tgccgtgagg aaagatgcat gagcgagccg ttaattgtcg
    14161 gcatccggca tcatagtccg gcctgcgccc ggctggtgaa atcgttaatc gaaagccagc
    14221 ggccacgata cgtattgatt gaaggcccgg ctgattttaa tgaccgggta gacgaactgt
    14281 ttttagccca ccagcttccg gtagctattt acagttattg ccagtatcag gacggtgcag
    14341 cccccgggcg tggtgcctgg acgccatttg ctgaattttc gccggagtgg caggcgctac
    14401 aagccgcacg tcgtattcag gcacaaactt acttcatcga tttgccttgc tgggcgcaga
    14461 gtgaagaagt ggacgattcg cctgatacgc aagaggaaag ccaggccttg ctgctgcgtg
    14521 ccacccgcat ggataacagc gacaccctgt gggatcactt gttcgaagat gaaagccagc
    14581 aaactgcatt accctctgca ctggcgcact attttgccca actgcggggc gactcccccg
    14641 gagatgctct caatcgtctg cgcgaagcct ttatggcccg ctggattgga tgggcgatgc
    14701 agcaaaataa tggcgacgtg ttagttgtct gcggtggctg gcacgctccg gtactggcaa
    14761 aaatgtggcg cgaatgcccg caggaaatta acacgccaga attgccgtcg ctggcagatg
    14821 ccgttacagg ttgttatctc accccctaca gtgaaaagcg ccttgatgtg ctggcaggat
    14881 acctttccgg aatgcctgcc ccggtctggc aaaactggtg ctggcagtgg ggcttacagc
    14941 aggcgggaga acaactgcta aaaacggttc tcacccgttt gcgccagcac aagttgcctg
    15001 cttcgaccgc ggatatggct gccgctcatc tgcatgcgat ggcactggca cagttgcgcg
    15061 gtcatacact accgttacgc actgactggc tggatgccat agcaggatcg ctgattaaag
    15121 aagccctgaa tgcgccgttg ccgtggagct atcgcggcgt tattcatccc gacaccgatc
    15181 cgattctgct aacgttgata gacacattag cgggtgacgg attcggtaaa cttgcccctt
    15241 ctacgccaca acctcctctg ccaaaagatg tcacctgcga actggaacgt accgcaatct
    15301 cccttccggc ggagcttacc ttaaatcgct ttaaccccaa tggactagcg caaagtcagg
    15361 tgttacatcg gctggcaata ctggagatcc cagggattgt gcgccagcag ggaagcacac
    15421 tgacacttgc aggcaacggt gaagaacgct ggaaattaac ccgcccgctt agccagcatg
    15481 cggcattgat tgaggccgcc tgctttggtg caacactcca ggaagccgca cgccataaat
    15541 tagaagccga tatgctggac gcgggtggaa tcggcagtat caccacatgt cttagccagg
    15601 cggcgttagc gggtctggcg tccttcagtc aacaattact ggagcaactc acattattaa
    15661 tcgcccagga aaatcaattt gccgaaatgg gccaggcgct ggaagtgcta tatgccttat
    15721 ggcggctgga tgaaattagc ggtatgcaag gcgcgcagat attacaaacg acgttatgcg
    15781 cggctatcga tcgcacgctg tggctatgtg aatctaacgg cagaccagat gaaaaggagt
    15841 ttcacgctca cctgcatagc tggcaagcgt tgtgtcatat cctgcgcgat ctacatagcg
    15901 gtgtgcaact ccccggcatt tctctttctg cggcggtagc cttactggag cgacgcagtc
    15961 aggcaattca tgccccggcg ctggatcgcg gcgcggctca tggcgcactg atgcgtctgg
    16021 aacatcctaa cgccagtgcc gaagcggcgc tgacgatgct ggcgcagtta tccccggcac
    16081 aatccggcga agcgctgcac ggtttgctgg cgctggcccg ccatcaactg gcctgtcagc
    16141 cgacatttat cgccggtttc agcagtcatt taaatcaact aagtgatgcc gattttatca
    16201 atgccctgcc cgatttacgc gcggcgatgg cctggctacc accacgagaa cgcgggacgc
    16261 tggcgcatca ggtgcttgag cattatcaac tggcgcaact tcccgtttcg gcgctgcaaa
    16321 tgccgttgca ttgtccacca caggccattg cacatcatca acaactcgaa cagcaggcac
    16381 tggcatcgct gcaaaactgg ggagttttcc atgtctgaac tgaacgatct tctgaccacc
    16441 cgtgagctac aacgctggcg attaattctt ggcgaagcgg cagaaacgac gctttgtggg
    16501 ctggatgaca acgcccggca gatagaccac gcgctggagt ggctgtatgg gcgcgatcct
    16561 gaacggctcc agcgtggtga acgctctggt ggattaggtg gctcaaatct caccacccct
    16621 gagtggatca acagtattca cactctgttt ccgcaacagg tgattgagcg actggaaagc
    16681 gatgccgtac tgcgctacgg cattgaagat gtggtgacga atctcgacgt gctggaacgt
    16741 atgcagcctt cggaaagcct gctacgcgcc gttttgcaca ccaaacatct gatgaatccc
    16801 gaagtactgg ctgccgcccg ccagatagtg cgccaggttg ttgaagaaat tatggcgcga
    16861 ctggcaaagg aagttcgtca ggctttttct ggtgtccgcg atcgccgtcg ccgctcatta
    16921 attccactgg cgcgaaactt tgatttcaaa agtactctgc gcgccaacct gcaacactgg
    16981 cacccgcaac acggcaagtt gtatatcgaa tccccccgct ttaacagccg cattaaacgc
    17041 caaagcgaac aatggcaact ggtcttactg gttgatcaaa gcggatcgat ggtggactcg
    17101 gtgatccact ctgcggtgat ggcggcctgt ttgtggcagt tacccggcat tcgtacccat
    17161 ctggtggcgt ttgacacaag cgtggttgat ctcacggcag acgttgccga tccggtagag
    17221 ttattaatga aagtacagtt gggcggcggg accaatatcg ccagtgccgt ggagtatggt
    17281 cggcaactta ttgaacaacc agcaaaaagc gtcattatcc tcgtgagcga tttttacgaa
    17341 gggggttcat catcattgct gacgcatcag gtgaaaaagt gtgtccagag cggcatcaaa
    17401 gtgctgggac tggcagcgct cgatagcacc gcaacgcctt gctatgaccg cgatacggcc
    17461 caggcgctgg ttaatgtcgg cgcacaaata gccgccatga cgccgggcga gctggcatca
    17521 tggcttgcgg agaatcttca gtcatgaatt cactacgtcc ggaattatta gaactgacac
    17581 cgcaggcact gacggcgtta agcaatgccg gttttgttaa gcgcagtctt aaggaactgg
    17641 aaaatggcaa cgtcccggaa atcagccatg agaacggcgc tttaatcgcc accttcagtg
    17701 acggtgtccg tacccagctg gcgaacagcc aggcactgaa agaggctcag tgcagctgcg
    17761 gggccagcgg catgtgccgt catcgcgtga tgctggtgtt aagttatcaa cgactttgtg
    17821 ccaccgtcca gcccacggaa aaagaagaag aatgggatcc ggcaatctgg ctggaagaac
    17881 tggctaccct gcccgatgcc acccgcaaac gcgcgcaggc gctggtcgct aaaggcatca
    17941 ccattgagtt gttctgtgcg ccgggcgaaa ttccctctgc ccgcttaccg atgagcgatg
    18001 tgcgttttta ttcccgtagc agtattcgtt tcgcccgttg tgattgtatt gaaggcacac
    18061 tttgcgaaca tgtcgtactg gctgtgcagg ccttcgtcga ggccaaagcg cagcaagcag
    18121 aatttaacca tttaatctgg cagatgcgca gcgaacacgt cacatcatct gacgatccgt
    18181 ttgccagcga agaaggccaa acgtgtcgtc aatatgttca gcaattaagc caggcattat
    18241 ggcttggcgg catcagccag ccgcttattc actacgaggc agcattcaac cgcgcattgc
    18301 aggcggcaga ggcctgcaac tggcgctggg tgagtgaatc actacgacag ctacgggcaa
    18361 gcgttgatgc cttccacact cgcgccagcc actatcatgc cggagaatgc ttacgtcagc
    18421 ttgcggcatt aaacagtcga ttaaattgcg cacaagagat ggcccggcgc gacagtgttg
    18481 gtgaagttcc tcctgtgccg tggcgcacgg tcgttggctc tggcattgcc ggagaagcaa
    18541 agcttgatca tctgcggctg gtgtctttag gtatgcgttg ctggcaggat attgagcatt
    18601 atggtttacg catctggttt accgatcccg acaccggcag tattttgcac ctttcgcgca
    18661 gttggccgcg aagtgaacag gaaaactcac cggcagctac gcgtcggctg tttagttttc
    18721 aggctggcgc actggcgggt gggcaaattg tttcacaagc agcaaaacgc agtgccgatg
    18781 gcgagctgct gttagctacc cgcaaccgct taagcagcgt tgtgccgctg tcgcctgatg
    18841 cctggcaaat gttgagcgcg ccgttacgcc agccgggcat tgtggctttg cgggaatatt
    18901 tacgccagcg tccccccgcc tgcatacggc ctcttaatca ggtcgataac ttatttattc
    18961 tgccggtcgc tgagtgtatt tcgctcggtt gggatagcag ccgccagacg ctggatgcgc
    19021 aggtaatcag cggcgaaggt gaagataatc tcctgacgtt atcccttccg gcatctgcct
    19081 gttctccttt tgccgttgaa cgcatggcgg cgcttttgca acaaacagac gaccccgtga
    19141 gtctggtttc tggctttgtc agttttgttg atgggcaatt gacactggaa ccacgggtga
    19201 tgatgacaaa aacccgcgcc tgggcgctgg acgcggaaac tgcgcctgtg gcaccgctac
    19261 cttctgccag cgttttgcct gtgccgtcta ccgctcatca gttgctgatg cgctgccagg
    19321 cgttacttat tcaactgctc cataacggct ggcgctatca ggaacagagc gctattagtc
    19381 aggcagagtt gctggcgaat gacctctccg cggtcggttt ttatcggctg gcacatgtgt
    19441 tgggacaatt tcgtaataca gaaagcgagg cacgggtaga agcaatgaat aacggtgttt
    19501 tactttgcga acaattattc cccatgcttc agcaacaagg atgaaatagt gctttttact
    19561 aagagttcta ctccagttcc ggactgctca cgtcacggta ttaggcatat tctatatagc
    19621 ccctggtgag agtcaccagt ttcttgatta aataaaatgg agttttacat gaaggctttc
    19681 aataagctgt tttccctcgt tgttgcatct gttctggttt tctctcttgc tggctgcggt
    19741 gacaaagaag aatcgaagaa attcagcgcc aatctgaacg gcactgaaat tgccattacc
    19801 tatgtctaca aaggtgacaa ggtgcttaag caatcttctg aaaccaaaat tcaatttgct
    19861 tctattggtg caaccaccaa agaagacgct gccaagacac ttgagccgtt aagcgccaaa
    19921 tacaaaaaca tcgcgggtgt tgaagaaaaa ttaacctata cagataccta cgcgcaggaa
    19981 aacgtgacta tcgatatgga aaaagtggat tttaaagccc tgcagggtat ttcaggaatc
    20041 aacgtttctg ctgaagatgc caaaaaaggt atcactatgg cgcaaatgga actggtgatg
    20101 aaagccgctg gttttaaaga agtgaaataa tctgtcggcg gccatgtttc gcatggccgc
    20161 catacccgtc ttagcttttc ttcacatgct ggcgcgctgc cagtccacgc agaaaataac
    20221 gtaaaaattg atcgccgcat tcgcggaagt ttttatgatc cggtgcgcgc atcatcgctg
    20281 taatttccgg catcgaaacg cggaactgct gttcggtgag gatagccaga atgtcatcgg
    20341 ttttcagcga aaacgcgatg cgtaattttt tcagcacgat gttgttatta atgcgacgtt
    20401 ccggctccag tgccggagca gactcatcct tgccgcgttt ttcataaatc aggccgttga
    20461 ggaatgacga caaaacaatg tccggacaac gctgaaaacc ctcttcgtct tctttacgta
    20521 gccagacggc gatctgttcc gcggtggctt cgacattacc cagcgccaga atacgcacca
    20581 ggtcattatt attggctttc aaaatgtagc gcacgctgcg cagaatatcg ttacttagca
    20641 tgaggccttc aggtgttgat gaggcaaaaa gccattttag cagtctttta caggccaatc
    20701 gcctctttta agcttttcag ataacggcgg ctgaccggca cggttaagcc attacgcaaa
    20761 atcaactcgg cctggccgtt atcttccaga cgaatctcct gtaaatgcgc gagattaacc
    20821 agatactgac gatggcagcg cagtagtggt gtacgacttt ccagggtacg taatgtcaat
    20881 tcggtaaagc cctctttccc ttcgtggctg gtaacgtaga caccgctcat ccgactgctg
    20941 acaaatgcca catctttcat ttgcagcaaa taaatccgac tatgccccgt acaagggata
    21001 aatttcagca cctgttgatt ttccggtaac agcgaaacat cctgcttgct gcgctcctga
    21061 cgcaatcgcg ccagcgtttt ctccagtcgc gcttcatcaa ttggcttcag cagataatca
    21121 aaagcatgtt cttcaaaggc tttaatagcg tattcgtcaa acgcggtgag aaaaacaata
    21181 tacggacgat gttccggatc gagcatcccc accatttcca gaccactgat gcgcggcatc
    21241 tggatatcga gaaacagcac atccgggcgc agtttatgca ccgcgccgat cccttccacg
    21301 gcgtttgaac actctccaac gatttcaata tcgctctgct cctgcaaaaa tacgcgcagg
    21361 ttctcccgtg ctaacggttc atcatcgaca attaagactt taatcatgcc tcgtccctcc
    21421 atggtagtcg taacgttatt cgggtgtaac tatcaggctc acaggcgacg cttatcccat
    21481 agtcatcgcc aaaccgttca cgtaaacgct tatccaccag attcatcccc agcccactgg
    21541 cattggttac cggttgatac aaaccggcat tgtcttcgat ctccagcatc aaatgttgcc
    21601 cctcacgtcg ggcgctgatt gccactcgcc ctgtatccag cagttgtgat gtcccatgtt
    21661 taatggcgtt ttccactatc ggttgcaggg taaacgcggg caattgctgc tgggataatt
    21721 cttgcggaat agcaatgttg acctgcaacc gcgactggaa gcgcgccttt tcaatttgca
    21781 gataagcatt cacatgttca atttcgtcgg cgagagtaac aaactccgaa ggccgcttta
    21841 agtttttgcg gaaaaaagtg gaaagatact gcaccagctg gctggcctgt tcgctgtcgc
    21901 gacggatcac cgctttaatg gtgttaagcg cattaaacaa aaaatggggg ttcacctggg
    21961 cgtgaagcag tttgatctct gactgggtga gcatcgcttt ttgccgctca tattgcccgg
    22021 caaggatctg cgccgaaagc aattgcgcaa tcccctcacc caacgtgcgg ttgattgaac
    22081 tgaataaacg gtttttggct tcatacaatt tgatggtgcc catcacccgc tgattttcac
    22141 cacgcaacgg aattaccagc gtcgacccca gtttgcattg cggatgcaaa gagcaacggt
    22201 aaggtacttc gttgccatca gcgtagacca cttcaccggt ttcaatcgct tttaaagtat
    22261 aagttgaaga aatcggtttg ccgggtaaat ggtggtcgtc accaattccg gtaaaggcca
    22321 gcaatttctc tcgatcggta atcgcgactg caccaatatc cagttcctga tacagcacct
    22381 gagccacttt catgctgttc acttcgttaa acccctggcg caaaatgcct tccgtcgagg
    22441 ctgccacttt cagcgcagtg gcagaaaaag ccgaagtgta tttttcaaac atcgcgcgtt
    22501 tatcgagcaa tatacgcata aacagcgccg cgccgacggt attggtgacc atcattggcg
    22561 cagcaatatt actcaccaga cgcaccgcat cttcataagg tcgggcgatc gcaaggatga
    22621 tcagcatttg caccatttca gcgacgaacg tgacggcacc ggcggtaatg gggttaaaga
    22681 ctttatcagt gcgcccgcgg cggatcagga tgctgtgtac caggccaccg agtaatcctt
    22741 caacgatggt cgagatcatg caacttaacg cggtcatgcc ccccatcgaa tatcgatgta
    22801 agccgccggt cagcccaacc agcccaccga cgaccggacc gccgagtaag ccgcccatta
    22861 ccgcgcctat cgcacgggta ttggcaatag aatcgtcaat gtgcaaccca aaccaggtgc
    22921 ccatgatgca gaagatggaa aagacgatgt agcagagaaa tttatgcggc agacgaaccg
    22981 tgacctgcat taacggtatg aataatggcg ttttactcat taaccatgca atgactaaaa
    23041 aaacgcacat ctgctgaagc agcagcaaca ccagattaaa atcgtacata cccgcaaacc
    23101 acacttccct ttaaaacgcg taacatacat tgcctgcgtt taactttctt tgaactcttg
    23161 cagaaaaatg agaattcgtg agtacgatca ctcaaaatcg cctggcaaaa ataaaatcac
    23221 cctatagatg cacaaaaaac gggcaaaact acctggttcg caaaactgcg tctaaagtta
    23281 aaccgggacc tcgcgagcaa gggtgagacg atggcgcttt acacaattgg tgaagtggcg
    23341 ttgctttgtg atattaatcc tgtcacgtta cgcgcgtggc agaggcgtta cggattgctg
    23401 aaaccgcaac ggacagacgg cggtcatcgg ctgttcaacg atgccgatat tgaccggatc
    23461 cgcgagatca aacgctggat cgacaacggc gtgcaggtca gcaaagttaa aatgctgctc
    23521 agtaatgaaa atgttgatgt gcagaacggc tggcgcgatc agcaagaaac attactgact
    23581 tacctgcaaa gcggcaatct acatagcctg cgaacgtgga tcaaagagcg cggtcaggat
    23641 taccccgccc agacactcac cacacatctg tttattcctc tgcgccgacg gcttcagtgc
    23701 caacaaccga ctctccaggc gctgctggcg atcctcgacg gcgtactgat caactacatc
    23761 gccatttgtc tggcttcggc acgtaaaaaa cagggtaaag atgcgctggt ggttggctgg
    23821 aatattcagg ataccacccg tctgtggctg gagggctgga ttgccagtca acaaggatgg
    23881 cgcattgatg tcctcgccca ctcgctcaat caactacgcc ctgaactatt cgaaggccgt
    23941 acattgctgg tgtggtgcgg tgaaaatcga acctccgccc aacagcagca actcaccagt
    24001 tggcaagaac aaggccatga tattttccca ctcggcattt aatgattcgt taacaaatgc
    24061 gctttactgt acaatccttt cgttaacata aggagtgcat tatgcgcata gctaaaattg
    24121 gggtcatcgc cctgttcctg tttatggcgt taggcggaat tggtggcgtc atgctcgcag
    24181 gttatacctt tattttgcgt gctggctaag cgcctgcacc agcctttcaa acaggcggtc
    24241 tgcgatgatc gccgccagtg ccaccagtaa cgccccctgg atcacatacg cggtattaaa
    24301 tccgctaagc ccgatgatga tgggcgtacc cagcgtgctg gcccctaccg ttgaggcgat
    24361 cgtcgccgta ccaatgttga taatcaccga agttcgcacg cccgccagaa tcaccggagc
    24421 cgccagcggt agctcgacct tacgcagtcg ctgaccacga ctcattccca tacctttcgc
    24481 aacttctgtc acgctggcat caatcgctcc cagcccggca agtgtcgcct gcaggacggg
    24541 cagcacaccg taaaggatca aggcgataat cgctggttgc agaccaaagc cgatcaccgg
    24601 aacggcgatc gccagcactg cgacggacgg aaaagtctgt ccaacggcgg caatagtttc
    24661 caccagtggg cgaaattccg cgccccacgg gcgagtgaca gcaattccgg caccagtgcc
    24721 aatgatcacc gcaaacaaac tcgaaattcc caccagccag aaatgagcca gtgccagagc
    24781 tgcaaaactt tcttgctgat aaacgggtcg tggcagttgt gggaacaagg cagcaaacag
    24841 cggctggctg taaggcagcc agaaaatcag cgccacaaac agagcaatga gccagaacag
    24901 cggatcgcgc aacatcttca tacgcttacg cctccaccag cagatcctga aaatgcagcg
    24961 tgccgcaagg ctggccctgc atgttcacca ccggcagcac ctcgcatccc cgcgcaacaa
    25021 acagagagag cgcatcgcgt agcgtcatct cttctgccag tgcctcacca tctgctcgtt
    25081 cttcgcgacg cacgtaatcc gccacactac gtaacgaaag caggcgcaca cccagttcac
    25141 tacgtccaaa aaactggcgg acaaaatcat tcgccggacg agtcagcatc gtcagcggat
    25201 tgccctgctg cactacttca ccgtgatcca tcaataccag atgttctgcc agccgtagcg
    25261 cctcatcaat atcatgagtg accagcacaa tggtacgccc cagcaaacgg tgaatgcgcg
    25321 tcatctcttg ttgcaacgcg ccgcgcgtta ccgggtccag tgcgccaaaa ggttcatcca
    25381 ttagtaagac ttgcggatcg gcagccagtg cacgcgccac tcccacacgt tgctgctgac
    25441 caccggaaag ctgatgcgga taacgctcac gcaaatttga ctccagcccc agtagcgcca
    25501 ttaattcgtc gatacgatcg tcaatccgcg cccgcgacca tttttgtaat tgcggcacgg
    25561 tagcgatgtt ttgcgccacg ctccagtggg ggaacaggcc aatagattga atggcatagc
    25621 ccatccggcg gcgcaactcc agtactggca gcgagcgaat ttcttctccg gcaaagcgga
    25681 tctctccgct gtcatgctcc accaggcggt taatcatttt cagggtggtg gatttgccgg
    25741 agccagatgt gccaatcagc accgaaaaac tcccttcctg aaaattgaga ttgagatcgt
    25801 taacggcttt ttgtgcgccg aacagtttgc tgacatggct aaattcaatc attacgtttc
    25861 accttcagca gtgcgataag caaatcgaac agcgcgtcgg taagcaccgc cagaacaatt
    25921 accgggatca cccccagcaa cactaaatca atggcgctgc ttagcagccc ctggaaaacc
    25981 agcgcaccaa aaccgcctgc gccgattaac gccgcaatca ccgccatacc tacagtttgc
    26041 accatcacca cccgcaggct gcgcagaaat accggtaacg ccagcggtaa ctgaacatgc
    26101 aggaaacgct gcgccccgct catccccatc gctctggcgc tttccagcac atcgcgcggg
    26161 atctggttca aaccgactac cacgccgcgc accagcggca gcaaggcata gagcaccagc
    26221 gcaatcagtg cgggtgtcat tccggttcct gctatgccga gcgtccccag ccacggaaag
    26281 gccgtaacca gcgcggcaag cggcgcaatc aacaggccaa agagcgccac cgaaggcacg
    26341 gtctgaatca cattgagcag agaaaaaatt gccccctgcc gagcagtgga aaagtagcac
    26401 cagatgccca acggcacacc aatcactaac gcaggcagca ccgcaccaaa cagcaacgtc
    26461 agatgttgtg ccagcgcgtc gtcaaacaca tcctgacggt tggcgtattc tttcattagt
    26521 gagagatcgt taagcgtgcc ggagtacagc aaccacagcg gaataatggc aatctgcata
    26581 tgcaacaacc agcgccacag cggatgcgtg gagattcggc ggatggcatc gctacaggcc
    26641 agcaatgcca gcgccgcagc cagccagaaa ccactgccga ggctggtacg cgccagcgca
    26701 ctgccatttt gcgccagttg ggtcgccgcc tttccagctc cccacaccag caatacgaag
    26761 acgaattgcg ccagaatgag tgcacaaatg ctgccttttt taccgggaat aaaacaggcc
    26821 gtcagccagg cgcaaccaac gcccaccagc atccagatcg tttgcggcca cagctgccag
    26881 agatgacgcc cctcacccga aactaaacga ttaggcgcgt aactgataaa cggcagcgcc
    26941 gctgcgattg ccgtcagcaa cagcagcagc gccagaacag gattaatacg gaaataagtc
    27001 acgggaaatt acttcgtcca ccctttttgt ttcaggtagt cggcagccac ttttttggca
    27061 tccagtcctt ccacagcaat gctggcattc agttgctgca atgtttttgc atcgaggctg
    27121 gcgaagactg gctgtagcca ctgtgccatt tgcggatact ccctcaacac cgactcacgc
    27181 accactggtg caggcgcgta gataggttgc acaccttgcg gatcgcttaa ggtttgcagc
    27241 cccagcgccg ctaccgggcc gtcagtgccg taagccattg cagcattaac gccagaggtt
    27301 tgctgggcag cggctttgat cgtcaccgcc gtgtcgccac cagccagtga cagcaactga
    27361 tcctgaccga gcttaaagcc ataggctttt tcaaacgcgg gtaacgcatc ggcgcgttcg
    27421 ataaactctg ccgaggctgc cagtttgaag gtgccgccct cttgcagata acgactcagg
    27481 tcggcaagcg aagtgagttt atttttctct gccacatcct gacgcacggc gatagtccag
    27541 gtgttatttg caggcgcggg cgtcagccag attaacttgt tgtgctccga atcgagcttt
    27601 ttgactttct cgtaaccttg ctgcgcgttt ttccacgctg catcgttttc atctttaaag
    27661 aagaaagcgc cattgccggt atattccgga tagatatcca gttcaccgga agtaatcgcc
    27721 ccgcgcacca caggagtcgt tccgagttgc actttattca ccgtcggtac gccgtggctt
    27781 tccagcacct gcaaaatgat attgccgagt agcgcacctt cggtatcgat ttttgaaccg
    27841 actttaacgg gggaagccgc ctgtagcggc aggctcacgg ctgccaacat aaccagtgaa
    27901 cctgcccaga gctttaagag tggcatgatg ctttcctcat tcttttactg ttgttttcag
    27961 cgaattaaga gaaaagcata gttgataatg gcggggttag cttgagcgga aggattcagt
    28021 tgcagaatca gataaatact taagaggcat attcggtccg gcgtttcctg ccggatgcgg
    28081 cgcgagcgcc ttatccggcc tacaaagggc gcaaacgtcg cgcccttact aaagcattac
    28141 agcaactcaa actcgccttt cttaacgcgt gcggaatcag tgccgataaa gacattgaac
    28201 ttgccaggct cggcgtcata tttcatctgt tgattccaga acttcagcgc ctcaatatcg
    28261 atcgggaagc tgacagtctg agtttcgccc ggtttcaggg tgattttctc aaagcctttc
    28321 agctgtttca cagggcgact catggaagcc gtcacatcct gcaagtacat ctgcactacc
    28381 gtggcaccct cgcgcttacc ggtgttcgtc acctgcacgc tggcagtcac tttgccgtca
    28441 cgcttcatgg tcggcgcaga aagtttcaca tcagagacgg tgaaagtggt gtagctcagc
    28501 ccatagccga acggatacaa cgccccgtta gcttcatcaa aataacgcga agtgtatttg
    28561 ttcggcttgt cggcattata cgggcgaccg gtattcagat ggctgtagta caccgggatc
    28621 tgcccgacag aacgcgggaa ggacattggc agcttgccgg acgggttgta atcgccaaac
    28681 aatacatcgg caattgcatt accgccttca gtccccgcaa accaggtttc cagaatcgca
    28741 tcagcctgct gatcttcttt caccagcgcc agcggacgcc cgttcatcag caccagcacc
    28801 agcggtttac cggtggcttt cagtgccgca atcaagtcac gttggctttg cggaatagtg
    28861 atatcggtcc ggctggaggc ttcgtgcgcc atcccctgtg cttcaccgac tacagccacc
    28921 accacatcag attgtttcgc cgtctgcacc gcttcatcaa tcatctcttg cggcgaacgc
    28981 ggatcgactt tgaccgcttc ttcatactga ttcaggaaat cgataatgcc tttgtcactg
    29041 gtaacgttcg cccctttggc atacagcact ttaccgtttt caccgacggc atttttaatc
    29101 ccggtcagta cggtcacgga ttgatcggca acaccggctg cggaccagct gcccatcacg
    29161 tcacgtttac tgtccgccag tggcccaacc accgcaatgg tggccgattt tttcagcggt
    29221 aacgtttcga gacggttttt cagcaacacc aagctttcgc gcgccacttc acgcgcttct
    29281 ttacggtgca ggcggctttc ggcattggta tccaccgggt cagactcttt cggccccaaa
    29341 tggctgtatg ggtcgttaaa caaccccata tcatatttaa cgttcagtac atggcgggca
    29401 gcatcgtcca gctctgccat cgtcactttg ccggatttaa tcaacccagg cagatacttc
    29461 gagtagtact cgtcgctcat gctcatgttg attccggatt tcagcgccac gcgcaccgca
    29521 tcttccgggt ctgccgccgt gccatgttta atcagctctt tgattgcacc gtgatcggaa
    29581 acggtgatgc ctttaaagcc ccactggtcg cgcagaacat ctttcagcag ccaggaatcg
    29641 gaggtggctg gcgtgccgtt cagcgagttc agcgccacca tcaccgcgcc gctgcctgcg
    29701 tccagccccg ctttgtacgg cggcatataa tcattaaaca ggcgctgcgg actcatatcg
    29761 acggtgttgt actctttacc gccttctacc gcgccgtatg cggcaaagtg tttgacgctg
    29821 gtcatcaccg agtagcgatc tgccgggctt ttaccctgca tcgcttccac catggtttta
    29881 cccattgttg aggtgagata cgtatcttcg ccaaaacctt cggaagcacg tccccagcgc
    29941 ggatcgcgcg agacatcgac catcggtgcc caggtcatat tcaggccatc atctgccgct
    30001 tcataagcag agacacgtcc gaccgttttc actgcatcga ggttaaaaga cgaggccaga
    30061 ccgaggctaa tcgggaacac cgtgcgctga ccgtgcagca cgtcgtaagc aaagaaaaga
    30121 ggaattttca ggcggcttaa ttccatcacc tgatcctgca tggcgcggat atcctgacgg
    30181 gttacggtgt tgaaaatcgc cccaacctga ccgtctttga tcatctcgcg gatcgcctct
    30241 ttcgggttat ccgggccgac gctgattaag cgcagctgac caattttctc atcaactgtc
    30301 attttcttaa gcagttcggt gacgaacgca tcccgcgctt cgggcgttaa tggatggttg
    30361 ccgaataaat catccgccag tgctggctgc agggccagac tcaccgcgat tcctactgaa
    30421 catagccatt tcatatggat ttttcttcct ttgttgcccg acgtggcagc gaaaatggtg
    30481 caaaaaccgt agtttgccat aagcatgatg gagagagaaa aagaatgctc agtttattgt
    30541 ctgaattttc aaaatattca ctcgctgaat tgttatacaa ggcgctattc tagtttgtga
    30601 tattttttcg ccaccacaag gagtggaaaa tgtcttccat gacaacaact gataataaag
    30661 cctttttgaa tgaacttgct cgtctggtgg gttcttcaca cctgctcacc gatcccgcaa
    30721 aaacggcccg ctatcgcaag ggcttccgtt ctggtcaggg cgacgcgctg gctgtcgttt
    30781 tccctggctc actactagaa ttgtggcggg tgctgaaagc ctgcgtcacc gccgacaaaa
    30841 ttattctgat gcaggccgcc aatacaggcc tgaccgaagg atcgacgcca aacggtaacg
    30901 attatgatcg cgatgtcgtt atcatcagca ccctgcgtct cgacaagctg cacgttcttg
    30961 gcaagggcga acaggtgctg gcctatccgg gcaccacgct ctattcgctg gaaaaagccc
    31021 tcaaaccgct gggacgcgaa ccgcactcag tgattggatc atcgtgtata ggcgcatcgg
    31081 tcatcggcgg tatttgtaac aactccggcg gctcgctggt gcaacgtggc ccggcgtata
    31141 ccgaaatgtc gttattcgcg cgtataaatg aagacggcaa actgacgctg gtgaaccatc
    31201 tggggattga tctgggcgaa acgccggagc agatccttag caagctggat gatgatcgca
    31261 tcaaagatga cgatgtgcgt cacgatggtc gtcacgccca cgattatgac tatgtccacc
    31321 gcgttcgtga tattgaagcc gacacgcccg cacgttataa cgccgatcct gatcggttat
    31381 ttgaatcttc tggttgcgcc gggaagctgg cggtctttgc agtacgtctt gataccttcg
    31441 aagcggaaaa aaatcagcag gtgttttata tcggcaccaa ccagccggaa gtgctgaccg
    31501 aaatccgccg tcatattctg gctaacttcg aaaatctgcc ggttgccggg gaatatatgc
    31561 accgggatat ctacgatatt gcggaaaaat acggcaaaga caccttcctg atgattgata
    31621 agttaggcac cgacaagatg ccgttcttct ttaatctcaa gggacgcacc gatgcgatgc
    31681 tggagaaagt gaaattcttc cgtccgcatt ttactgaccg tgcgatgcaa aaattcggtc
    31741 acctgttccc cagccattta ccgccgcgca tgaaaaactg gcgcgataaa tacgagcatc
    31801 atctgctgtt aaaaatggcg ggcgatggcg tgggcgaagc caaatcgtgg ctggtggatt
    31861 atttcaaaca ggccgaaggc gatttctttg tctgtacgcc ggaggaaggc agcaaagcgt
    31921 ttttacaccg tttcgccgct gcgggcgcag caattcgtta tcaggcggtg cattccgatg
    31981 aagtcgaaga cattctggcg ttggatatcg ctctgcggcg taacgacacc gagtggtatg
    32041 agcatttacc gccggagatc gacagccagc tggtgcacaa gctctattac ggccatttta
    32101 tgtgctatgt cttccatcag gattacatag tgaaaaaagg cgtggatgtg catgcgttaa
    32161 aagaacagat gctggaactg ctacagcagc gcggcgcgca gtaccctgcc gagcataacg
    32221 tcggtcattt gtataaagca ccggagacgt tgcagaagtt ctatcgcgag aacgatccga
    32281 ccaacagcat gaatccgggg atcggtaaaa ccagtaaacg gaaaaactgg caggaagtgg
    32341 agtaaaaatt acggatggca gagtatcgcc atccgaattc acttaatcgt tctgtgccgt
    32401 ctgccccgcc gccgccattt gggcggcttt ttgtttttta tagctcaacg ctgctgccgg
    32461 cacaggcatc actttaccgg tttcaatcca ggtacgcagg cggctggcat cggcaaaatg
    32521 ggtatatttg ccaaacgcgt ccatcactac cagcgccacc ggtttattat tgataaccgt
    32581 acgcatcacc agacaatggc ccgccgcatt ggtaaagccg gttttggtta actgaatatt
    32641 ccagttatcg cgatacacca gatgattagt attgcggaac ggcagcgtat acgtcggatt
    32701 agagaaggtt gccatatctt cccgggtagt acttaactgc ccgatcaacg gatattgttt
    32761 gctggcaatg agcagtttgg ttaagtcacg ggcagttgaa acgttatgca ccgacaatcc
    32821 ggtaggttca acaaagcgcg tgttgttcat tccgagcgat ttcgctttcg cattcattgc
    32881 cttaataaag gctttgtaac caccgggata atggtgcgca aggcttgccg ccgcgcggtt
    32941 ttctgaagac atcagcgcca gcaacagcat atctttacgg ctgatttcgc tattcagtcg
    33001 tacgcgcgaa tagacccctt tcatctccgg cgtctggctg atatccactt ttagtttttc
    33061 atccagcggc agtcgtgcat ccagcacaac catcgcggtc attaatttgc tgatagacgc
    33121 aatcggacgc accagatccg ggtggttcga atagatcact ttgttggtat tcagatcaac
    33181 aatcatcgcg ctaccggagg caatttccgg ttgtgaagcg gtggtagcgg ctgccgtttt
    33241 cgcaacggcc tgcggtgcaa aaggcacagc cagcatcagg gccaggctaa ataaagaaac
    33301 tcgaaatttc ggcatgatga gcattcagat agtggttcac gcgcacgggt tgcgcaccgc
    33361 cggagtaagg atttactgag gctagcgacg ccatcataac gagcaaaaag tgcgatcgtc
    33421 aaaggagaat cgtgaggaaa tgctgcattg ctgacattta cgccagcaat gcaacgtcaa
    33481 agaactttct agaacaaacg ataaccgtag ccccatagta taacggttag ggcgagcagc
    33541 acttccagta ccagcacgcc aatcgccagc gtcgaactag agaagctaag gccttcctct
    33601 ttgttgatat tcaggaagct cggaatacca aggtaaagca ggtagccggt gtaaaacagc
    33661 gccaccgtgc cgaccagcgc acacaaccag accagtggat aaagcgccac cagaccgctt
    33721 aaaaacagcg gagttgcaac gtagcccgcg aagaccatgc agtgcgcaag tgacggacgc
    33781 tgcggataat tacgcgccat ccaccagatg acccgcccca tcaccgcgac cccagccagc
    33841 ataacgccgt aaaacaagac agccagcgcc agtccggtaa accaggataa cttcaggata
    33901 gtgccatcgc caaaattcca gccaatctgt gtagtgccaa tgaaggcgca aatcaccgga
    33961 atcgccgcca tcagcaaaac gtggtgggtg taatggtgag aaatcgtttc gttttcgcga
    34021 ttaatcacct gcatttcacg atcgggatgg gaaaacagtc cccagacatg gctcataccg
    34081 cccccttgtt gtgagttcat gaacctgaca gttcaagtat aagtcagctt gtgattattt
    34141 tttgttcgcc catgtaattt tcactgtctg atgaacgtcc tttttcagcg tgaatgattc
    34201 acagggtgta tgcttactgg caaccaaagg gagacagact ggcctatgga tctcaataca
    34261 cttatctcac aatatggtta tgccgcgctg gtgatcggta gcctggcgga aggtgaaacc
    34321 gtgactttgc tgggaggcgt tgcggcgcat caggggctat taaagttccc gctggtggta
    34381 ctttctgtgg cgcttggcgg catgattggc gaccaggtgc tctatctgtg cgggcggcgg
    34441 tttggcggca agctgttacg ccgtttctcg aaacatcagg ataaaattga gcgggcgcag
    34501 aaacttatcc aacgccatcc gtatctgttt gtcattggta cgcgctttat gtatggcttt
    34561 cgggtgattg gcccgacgct gattggtgcc agccagctgc cgccgaaaat ctttctgccg
    34621 ctgaatattc tcggcgcatt tgcctgggcg ttgattttta ccactattgg ttacgctggt
    34681 ggtcaggtga ttgcgccgtg gttgcacaat ctcgaccagc atttgaagca ctgggtctgg
    34741 ttgattctgg tcgtggttct ggtggtgggc gtgcgctggt ggctgaaacg acgcgggaag
    34801 aaaaagccgg atcatcaggc gtaaaaccat tgccctggat aaggcgttcg cgccgcatcc
    34861 gacatccgga gtaccatgcc tgatacgacg cttgtgcgtc ttttcatgcc gaccaaaata
    34921 ttacccaatg aaatatccac gcacctcact gcgctattct gggttgaact gtggattcgc
    34981 caacataaag ccgccatcca ctatcaacga ctgcccggtg gtgtaatttg cgccctccga
    35041 acaaagccac accaccaggc tggcaatctc atgcgttgcg ccaaaacgcc gcaagggaat
    35101 cgaaggctcc gcgtcgggct tcacgtcgct gtcatccatg ccattcattg gcgtggcgat
    35161 cgccccaggc gcgactgcgt tcaccaaaat cttatgcctg accagctcca gcgccatcgc
    35221 tttggttaac ccaccgagcg catgtttagc ggctgtgtag gcgctggcat ccggcagcgg
    35281 cgtatgttca tgtaccgacg taatgttgat gatgcgaccg ccctgccctt gtttcaccat
    35341 ctgacgagcc gcaatttgcg agcataagaa tgcaccatcg acatcaacgg taaaaatctt
    35401 gcgccactca tcaaaagcca tatcaagaaa cggcgctttg gtcattgcac ccgcattatt
    35461 caccagcaca tcaatgcgcc ccagccgttg aatgagtttc tccagcgcca gtgccccttc
    35521 tggtagattg ccgagatcca gctgcacgat ctccgcacgt acgccgtggc taactacctc
    35581 acgcgcggta tcttttgccc cttcttcatc tgagtgccag gtaataccaa tatcaaaccc
    35641 ctgctgcgcc agtaataacg cgcactcttt gccgatcccc gaatcggagg cggtaataat
    35701 cgcaacctgt gccatcgagt tctccactta acgctgaata aacgttaagt atagaaggcg
    35761 catatcatca gcgtttgtaa cccccgccca acgcaccagt gagttgaatg gaggcatcca
    35821 gccactgccc ttgcaataac aggccattgg cccgctcacg cagcgcgggg attctggctt
    35881 cgctgacgcg ggaaccagca atgatgcccg cgttaaagcg cgcctgcgca agacctacca
    35941 cacgcaaggc atcgcgctca atttgcgcct gatgctggtt tttctccgcc agtgtctgaa
    36001 cctgactggc tgcccgcgcc acgtcattca ccgcttcaac caccgctttg ttgtagctgg
    36061 cgatagacaa gttgctttcg gcttttgcga tatcgagatt ggcgttaaga cgaccactat
    36121 cgaaaatggg tagcgtcagg cctgccgtaa cgcccatttg ctgcgcggaa tgacggaaca
    36181 gatcgcttaa gtgcaacgca tcctgttgca ggaaggccat caggttgatg tcaggataaa
    36241 atgccgcttt tgccgcatca atggtgctta gcgatgactc aacgtaccag tgcgccgcct
    36301 gcaaatctgc ccgccgggcc agtaaggagt accccagttc atcaggaagc tggcttgcca
    36361 ctttcggcaa cgcgaccggt ttaagcttca atgactttgt ctggttattt gtaagtgcgc
    36421 ttaaccgtgc ctcaataatt ttcattttcc ccgcgacatc gttgagctgc tgccgggttt
    36481 tgctggcatt aatatcggtt tccacacctt caactgaaga agtaatcccg ttctgatata
    36541 gctggcgatc ggtcgcgata atggtgttct gctctttttc tatttgctgc aagaccgtgt
    36601 ttaacgccgc ctgggtttgc cactcccagt acaggcgggc tacgctgcca gccagcaatt
    36661 ggcgggtttg ctcgcgttcc gccgcccgtg ctttaaccgt acccaggcgg gcagtaacct
    36721 ccgcccgatt ctttccccag atatcgagat gccagcccgc cgttaagcca aaagtaccgt
    36781 tggtgtacca cgggccggtc gtacctgcgg ccggatcgtt cagagcaaac ggccccatta
    36841 agccttctgc cgacattttt tgccgctcca tatccgccga aaagtcgatc tgcggaccat
    36901 cctgagtggc aactgccttc gcctgggctt cagctagctg aatgcgctgt tcagccacct
    36961 gcatatccgg tgcgttctgt agtgcattgt taattaagga agtgagttga ttatcgtgat
    37021 actccagcca ccattggctg tctggccaac catttttcag cgccttgggt aatgcggtgt
    37081 caacttgtgc agcgggcgtt tgctggctta acgcctggcg ggtttcatgc ataggcgcac
    37141 acccggccag catcagtaac agcggaaaac aggcgatggc tggataaaag gaatcacgat
    37201 tcatggggga ataatcaggt aagaaaaggt gcgcggagat taccgtgtgt tgcgatatat
    37261 tttttagttt cgcgtggcaa tacatcagtg gcaataaaac gacatatcca gaaaaatata
    37321 cactaagtga atgatatctt ccgatttatc ttaatcgttt atggataacg gcaaagggct
    37381 tcgttttttc ctatacttat tcagcactca caaataaagg aacgccaatg aaaattatac
    37441 tctgggctgt attgattatt ttcctgattg ggctactggt ggtgactggc gtatttaaga
    37501 tgatatttta aaattaatta atgtcatcag gtccgaaaat aacgagaata tttcagtctc
    37561 tcatcctgtt gcgctcctgt catgtgcatt gcttcatata a
//
LOCUS       DAPHKZ010000038        36458 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.038, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000038 DAPHKZ010000000
VERSION     DAPHKZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36458
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.038"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(456..1031)
                     /locus_tag="RH288_001959"
     CDS             complement(456..1031)
                     /locus_tag="RH288_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HDV4031014.1"
                     /translation="MTQSEMLKLIARHGYNVGFGAKKNFATYDLICKASGWISFISLA
                     VGVFALFIPELATNVISAILIIFGVATMYIQFYDSEKQSYESAGIEQTKIFNELEVIY
                     RNVKSDANFDYQRTQQSIDAIMSRFYGTVISKQIFGSNWYAHYKFYCEFEKAWVEEEL
                     NLTLKDKIPLSLCFLAGLAIIFTIAVIWKTP"
     gene            complement(1039..2367)
                     /locus_tag="RH288_001960"
     CDS             complement(1039..2367)
                     /locus_tag="RH288_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDV4031015.1"
                     /translation="MSHRELFSEFLENLNLDLKQAKKISYHYRKITKSLNLAFRGTSS
                     RVANRLKVGSVGRHTAIKGISDLDMLYIMPPNQYEYYNRKDNGQSALLTDVRNILAEE
                     YPDQTVKKDRLVVQIIFKNFYVEVQPVFRQDDDSFKFPESYNGGAWRITKPLHEKAAM
                     TAFSRDKSNNLRKLCKMIRAWKNLHGVNMGGLLIDTLAYRFLSSTSDYDNTGNGSLGA
                     LARDFFEYLSNEERKERYLALGSNQHVRVKSPWFGRAAKHAYELCCDALDAEGAASEN
                     DRWRKVFGRAFPRRKVGIMEARLGLESHAADAVPWTDTEEFIEDKYPVDIRYSLNLDC
                     TVTQDGFPPRSLREMLTRRFRLSARKSLLFRADLTEMEAEEPYTVMWKVLNVGDEARR
                     RNMIRGQIVSDGGYCTKKETTDFRGDHMVECYVIKNEVVVARAQIEVPIS"
     gene            complement(2502..2945)
                     /locus_tag="RH288_001961"
                     /pseudo
     CDS             complement(2502..2945)
                     /locus_tag="RH288_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3000..3314
                     /locus_tag="RH288_001962"
                     /pseudo
     CDS             3000..3314
                     /locus_tag="RH288_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743492.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(3324..3716)
                     /locus_tag="RH288_001963"
                     /pseudo
     CDS             complement(3324..3716)
                     /locus_tag="RH288_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707145.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(3748..3928)
                     /locus_tag="RH288_001964"
                     /pseudo
     CDS             complement(3748..3928)
                     /locus_tag="RH288_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            complement(4097..5359)
                     /locus_tag="RH288_001965"
     CDS             complement(4097..5359)
                     /locus_tag="RH288_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDV4031016.1"
                     /translation="MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRI
                     LGKEKTLALGVYPEVSLSEARTKRDEARKLISEGIDPCEQKRVKKVVPDLQLSFEHIA
                     RRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
                     ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALNLSRLPELLSRIDG
                     YKGQPVTRLAVMLNLLVFIRSSELRYARWSEIDIDNAMWTIPAEREPLPGVKFSHRGS
                     KMRTPHLVPLSKQAVAILAELQTWAGENGLIFTGAHDPCKPISENTVNKALRVMGYDT
                     TQDVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLML
                     QWWADFLNANREKCISPFDYAKINNPLK"
     gene            complement(5557..5632)
                     /locus_tag="RH288_001966"
     tRNA            complement(5557..5632)
                     /locus_tag="RH288_001966"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5597..5599),aa:Phe,seq:gaa)
     gene            complement(5738..6445)
                     /locus_tag="RH288_001967"
     CDS             complement(5738..6445)
                     /locus_tag="RH288_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDV4031017.1"
                     /translation="MVIGPFINASAVLLGGVLGALLSQRLPERIRVSMTSIFGLASLG
                     IGILLVVKCANLPAMVLATLLGALIGEIGLLEKGVNTAVAKAQNLFRHSRKKPAHESF
                     IQNYVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
                     SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLP
                     ALLLAMPLSAAWTAWFA"
     gene            6843..8978
                     /gene="speC"
                     /locus_tag="RH288_001968"
     CDS             6843..8978
                     /gene="speC"
                     /locus_tag="RH288_001968"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417440.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
                     /protein_id="HDV4031018.1"
                     /translation="MKSMNIAASSELVSRLSSHRRVVALGDTDFTDVAAVVITAADSR
                     SGILALLKRTGFHLPVFLYSEHAVELPAGVTAVINGNEQQWLELESAACQYEENLLPP
                     FYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGD
                     LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKS
                     NHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPYR
                     LAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLELNE
                     NDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP
                     LFAALDVNAKIHEGESGRRLWAECVEIGIEARKAILARCKLFRPFIPPVVDGKLWQDY
                     PTSVLASDRRFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVP
                     ATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLVE
                     VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAH
                     SAYIRGDVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNL
                     LPGFSPELQGVYSETDADGMKRLYGYVLK"
     gene            complement(9028..10284)
                     /gene="nupG"
                     /locus_tag="RH288_001969"
     CDS             complement(9028..10284)
                     /gene="nupG"
                     /locus_tag="RH288_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupG"
                     /protein_id="HDV4031019.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAQVTTPEAMFLVILIN
                     SFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
                     QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSM
                     LLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLS
                     RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVE
                     KEVSPAIRASAQGMFLMMTNGFGCILGGIVSGRVVEMYTQNGITDWQTVWLIFAGYSV
                     VLAFAFMAMFKYKHVRVPTGTQTVSH"
     gene            complement(10486..11565)
                     /gene="mltC"
                     /locus_tag="RH288_001970"
     CDS             complement(10486..11565)
                     /gene="mltC"
                     /locus_tag="RH288_001970"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HDV4031020.1"
                     /translation="MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQF
                     AHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRA
                     IIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
                     NRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTES
                     SFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAM
                     LNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLT
                     TRHPSAESRRYLYKVNTAQKSYRRR"
     gene            complement(11630..11905)
                     /locus_tag="RH288_001971"
     CDS             complement(11630..11905)
                     /locus_tag="RH288_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HDV4031021.1"
                     /translation="MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK"
     gene            complement(11933..12985)
                     /gene="mutY"
                     /locus_tag="RH288_001972"
     CDS             complement(11933..12985)
                     /gene="mutY"
                     /locus_tag="RH288_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDV4031022.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQ
                     VATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGG
                     KFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEV
                     ENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWAL
                     YPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRQWLAQ
                     RQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFTGCMDEGNALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            13146..13865
                     /gene="trmB"
                     /locus_tag="RH288_001973"
     CDS             13146..13865
                     /gene="trmB"
                     /locus_tag="RH288_001973"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDV4031023.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGA
                     CLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            13865..14191
                     /locus_tag="RH288_001974"
     CDS             13865..14191
                     /locus_tag="RH288_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417434.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HDV4031024.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLDEVRTSEL
                     FDVWWD"
     gene            14375..15094
                     /locus_tag="RH288_001975"
     CDS             14375..15094
                     /locus_tag="RH288_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HDV4031025.1"
                     /translation="MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIAL
                     DKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLV
                     NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGNLK"
     gene            15270..16316
                     /gene="ansB"
                     /locus_tag="RH288_001976"
     CDS             15270..16316
                     /gene="ansB"
                     /locus_tag="RH288_001976"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HDV4031026.1"
                     /translation="MEFFKKTALAALVMGFSGAALALPNITIFATGGTIAGGGDSATK
                     SNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKT
                     DGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARK
                     HTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVF
                     DTLATAAKTGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPQQIQQIFNQY"
     gene            16433..17440
                     /locus_tag="RH288_001977"
     CDS             16433..17440
                     /locus_tag="RH288_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 family protein"
                     /protein_id="HDV4031027.1"
                     /translation="MKKQWIVGTALLMLMTGNVWADGEPPTENILKDQFKKQYHGILK
                     LDAITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQLADYELLEQTWTKDKPVKFSAM
                     LTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALN
                     TQKNSIPALEKEVKALDKQMVAAQKAADAYWGKDANGKQMTREDAFKKIHQQRDEFNK
                     QNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVPIQQKRDFDINEQRRQTFLQSQKLS
                     RKLQDDWVTLEKGQYPLTMKVSEINSKKVAILMKIDDINQANERWKKDTEQLRRNGVI
                     K"
     gene            complement(17595..18731)
                     /gene="hemW"
                     /locus_tag="RH288_001978"
     CDS             complement(17595..18731)
                     /gene="hemW"
                     /locus_tag="RH288_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HDV4031028.1"
                     /translation="MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     NDLDNDVAYAQGREVKTIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEANP
                     GTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
                     NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGFMQGRYLESQRDVEATDKPFEFFMNRFRLLEAAPRVEFIAYTGLC
                     EDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE"
     gene            complement(18724..19317)
                     /gene="rdgB"
                     /locus_tag="RH288_001979"
     CDS             complement(18724..19317)
                     /gene="rdgB"
                     /locus_tag="RH288_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RdgB/HAM1 family non-canonical purine NTP
                     pyrophosphatase"
                     /protein_id="HDV4031029.1"
                     /translation="MQKVVLATGNVGKVRELASLLSDFGLDIVAQTDLGVDSAEETGL
                     TFIENAILKARHAAKVTALPAIADDSGLAVDVLGGAPGIYSARYSGEDATDQKNLQKL
                     LETMKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            complement(19325..19615)
                     /locus_tag="RH288_001980"
     CDS             complement(19325..19615)
                     /locus_tag="RH288_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HDV4031030.1"
                     /translation="MNAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN"
     gene            complement(19612..20178)
                     /gene="yggT"
                     /locus_tag="RH288_001981"
     CDS             complement(19612..20178)
                     /gene="yggT"
                     /locus_tag="RH288_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic shock tolerance protein YggT"
                     /protein_id="HDV4031031.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVT
                     QPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
                     LLYVINMGVAEVLQATGNMLLPGLWMAL"
     gene            complement(20196..20900)
                     /gene="yggS"
                     /locus_tag="RH288_001982"
     CDS             complement(20196..20900)
                     /gene="yggS"
                     /locus_tag="RH288_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate homeostasis protein"
                     /protein_id="HDV4031032.1"
                     /translation="MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIA
                     EAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
                     RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYSKK"
     gene            20918..21898
                     /locus_tag="RH288_001983"
     CDS             20918..21898
                     /locus_tag="RH288_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDV4031033.1"
                     /translation="MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDTPDV
                     EELLREWLDDDQRAILLENGQLDFAVSLAENQRLRGSAFAQRHGISLALRLLPSHCPQ
                     LEQLGAPTVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVE
                     YLYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVAL
                     FELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMITFQQSYQHRVGEGRL"
     gene            complement(22082..22498)
                     /gene="ruvX"
                     /locus_tag="RH288_001984"
     CDS             complement(22082..22498)
                     /gene="ruvX"
                     /locus_tag="RH288_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDV4031034.1"
                     /translation="MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNI
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVE
                     ARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(22498..23061)
                     /locus_tag="RH288_001985"
     CDS             complement(22498..23061)
                     /locus_tag="RH288_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HDV4031035.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLE
                     NLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDN
                     TVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKT
                     PIADRWREAAKLIGVDILTMPGVAGHA"
     gene            complement(23170..24120)
                     /gene="gshB"
                     /locus_tag="RH288_001986"
     CDS             complement(23170..24120)
                     /gene="gshB"
                     /locus_tag="RH288_001986"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HDV4031036.1"
                     /translation="MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLY
                     LINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYIL
                     ERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
                     PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIG
                     DRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ"
     gene            complement(24133..24864)
                     /gene="rsmE"
                     /locus_tag="RH288_001987"
     CDS             complement(24133..24864)
                     /gene="rsmE"
                     /locus_tag="RH288_001987"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003853382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDV4031037.1"
                     /translation="MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFD
                     GSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
                     AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            complement(24944..25651)
                     /gene="endA"
                     /locus_tag="RH288_001988"
     CDS             complement(24944..25651)
                     /gene="endA"
                     /locus_tag="RH288_001988"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HDV4031038.1"
                     /translation="MYRYLSIAAVVLSAAFSGPALAEGINSFSQAKAAAVKVHADAPG
                     TFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
                     AAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWNKMYPVTDWECERDERIAKV
                     QGNHNPYVQRACQARKS"
     gene            complement(25746..26243)
                     /locus_tag="RH288_001989"
     CDS             complement(25746..26243)
                     /locus_tag="RH288_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HDV4031039.1"
                     /translation="MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRG
                     TSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWM
                     MENVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGE
                     QLVAK"
     gene            complement(26320..27714)
                     /gene="galP"
                     /locus_tag="RH288_001990"
     CDS             complement(26320..27714)
                     /gene="galP"
                     /locus_tag="RH288_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HDV4031040.1"
                     /translation="MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIA
                     DEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVL
                     GTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
     gene            complement(28138..29292)
                     /gene="metK"
                     /locus_tag="RH288_001991"
     CDS             complement(28138..29292)
                     /gene="metK"
                     /locus_tag="RH288_001991"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDV4031041.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLT
                     SATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK"
     gene            complement(29596..29811)
                     /locus_tag="RH288_001992"
     CDS             complement(29596..29811)
                     /locus_tag="RH288_001992"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031042.1"
                     /translation="MGITSAGMQSRDAECGERIFTRTVRQVKQQTTVHYFVSPPRPPV
                     KTNPQAKTLISTRLEVATRKKRRVLFI"
     gene            29947..30078
                     /gene="yqgB"
                     /locus_tag="RH288_001993"
     CDS             29947..30078
                     /gene="yqgB"
                     /locus_tag="RH288_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HDV4031043.1"
                     /translation="MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII"
     gene            30087..32063
                     /gene="speA"
                     /locus_tag="RH288_001994"
     CDS             30087..32063
                     /gene="speA"
                     /locus_tag="RH288_001994"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HDV4031044.1"
                     /translation="MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAE
                     DAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGIFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQF
                     RDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE"
     gene            32201..33121
                     /gene="speB"
                     /locus_tag="RH288_001995"
     CDS             32201..33121
                     /gene="speB"
                     /locus_tag="RH288_001995"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDV4031045.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(33327..34085)
                     /gene="loiP"
                     /locus_tag="RH288_001996"
                     /gene_synonym="yggG"
     CDS             complement(33327..34085)
                     /gene="loiP"
                     /locus_tag="RH288_001996"
                     /gene_synonym="yggG"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417411.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease LoiP"
                     /protein_id="HDV4031046.1"
                     /translation="MKIRALLVAMSVATVLTGCQNMDSNGLLSSGAEAFQAYSLSDAQ
                     VKTLSDQACQEMDSKATIAPANSEYAKRLTTIANALGNNINGQPVNYKVYMAKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASA
                     GGIVGSLSQSQLGNLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLA
                     KLEEGRQSSMFDDHPASAERAQHIRDRMSADGIK"
     gene            34363..36354
                     /gene="tkt"
                     /locus_tag="RH288_001997"
     CDS             34363..36354
                     /gene="tkt"
                     /locus_tag="RH288_001997"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDV4031047.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDG
                     HDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMP
                     SDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVG
                     LNGAIVGMTTFGESAPAELLFEEFGFTVDNVVAKAKELL"
BASE COUNT         8845 a         9216 c         9459 g         8938 t
ORIGIN      
        1 atgagcaagg cggatttata tagtttgtaa ttagtttaaa tgtaagcagt tcgtcagagt
       61 gcgtattccg ctctattcga tcacggattg gccgttatga cccgatctcg atggaagtta
      121 ttgggtgatc cccttccatg aaaatataca ccgaagctcc cgcagaggtt tccgtgggcg
      181 aaggcatgat tctgtccgag agccggatgt gttagaagcg catgtccgct tcgatgagcg
      241 gggtgtggaa acaggattta tggtcaggac agtaaggcac cgccaatcga aagaggcggc
      301 aacagatatg cctgacctgt aaaattaccg cgccacatct tgactctacc cgttttccaa
      361 gcgccccccc ttatagaacg tacactggat ggtgataccg gctatacatc gcatatttga
      421 cagtcagctt gctgaatttt tcattggctg cagcatcagg gcgttttcca gatgacagct
      481 atagtaaaaa tgatcgccag accggcgaga aagcagagcg aaagcgggat tttgtccttc
      541 agtgtcaggt tcagctcttc ttcaacccat gctttttcaa attcacagta aaatttataa
      601 tgtgcgtacc agttacttcc gaagatctgt ttgctgatga ccgtgccgta aaaccgggac
      661 atgatagcgt cgatggattg ttgtgtacgc tgatagtcaa agtttgcatc gctttttacg
      721 ttgcggtaga tgacttcaag ttcattaaaa attttggtct gctcaatccc cgcactttca
      781 taactctgct tttccgagtc ataaaactga atgtacattg tagcaacacc aaatataatt
      841 aatatcgcgg aaatgacgtt tgtggccagc tcaggaataa aaagggcgaa cacaccgaca
      901 gcaagagaaa taaagctaat ccaaccggat gccttacaaa tcagatcata ggtggcaaag
      961 tttttcttag cgccaaatcc aacgttataa ccatgtcggg cgattaattt cagcatctct
     1021 gattgcgtca taaaaacctc agcttatggg aacttcaatc tgggcccggg caaccacaac
     1081 ctcatttttt atcacatagc attctaccat gtgatctccg cggaagtcgg tagtttcttt
     1141 cttcgtacag tagccgccgt ccgaaacgat ttgtccccgg atcatatttc ttctgcgtgc
     1201 ttcgtcaccc acgttcagta ccttccacat aacggtgtag ggttcctctg cctccatttc
     1261 tgttaagtct gcccggaaaa ggagagattt tcgagcggag aggcggaatc ttctggtaag
     1321 catctccctc aggcttctgg gagggaaacc atcctgggtt acggtacagt caaggttgag
     1381 tgagtacctg atatccaccg gatatttatc ctctataaac tcttcggtat cggtccaggg
     1441 aacagcatct gccgcatgcg attccagacc aagacgggct tccataatac ccactttacg
     1501 tctggggaag gctcgtccga acactttgcg ccagcggtca ttttcactgg cagccccctc
     1561 agcgtctaag gcatcacaac ataattcata cgcgtgtttc gctgcccggc caaaccaggg
     1621 agatttaaca cgtacatgct gattactgcc taacgcgaga tacctttcct ttctctcctc
     1681 atttgacaga tattcaaaaa agtctctggc gagggctccc aggctgccat ttccggtatt
     1741 gtcataatct gatgttgatg aaagaaagcg atacgctagt gtgtctatca gtaagccacc
     1801 catattgacg ccatgcaggt tcttccaggc tctgatcatt ttacacagct tgcgcagatt
     1861 attggattta tctcgcgaaa atgcggtcat ggccgccttt tcgtgaagag gttttgtaat
     1921 gcgccatgct cctccattat agctttcagg gaatttaaag ctgtcatcat cctgtctgaa
     1981 tacaggttga acctcgacat aaaagttttt aaagatgatc tgaacaacca gtctgtcctt
     2041 tttcacagtc tggtcaggat attcttccgc cagaatgttt ctgacatctg taagcaatgc
     2101 agactgacca ttatccttac ggttataata ttcatactga ttggggggca taatataaag
     2161 catatccaga tcggatatgc cttttattgc ggtatgtctg cctactgacc ccactttcaa
     2221 gcggtttgct acccgggaac tcgttcctct gaacgcaaga tttaatgact tggttatttt
     2281 tcgatagtga tagctgatct tttttgcctg tttgaggtca agattcaaat tttcaagaaa
     2341 ttcgctgaac aattccctgt ggctcatggt gtttcctttg gcatgtgaaa cattagctta
     2401 cattatcatt acaccttata aaaaccaaga tcttgggagg tgagcgttct gcatggcttt
     2461 atgacttaaa cgtaagcgtt aacggagtgc cgtattgacg cttatttatt ggtgagtact
     2521 acgttccatg gcaggagttc gtcaactcgg ttggaaggcc attccggcag tacgctcagg
     2581 atatggcgca gatacgcttc cggatcgata ccgttcagtc ggcaggtgcc gatcagcccg
     2641 tacaacagtg ctcctcgctc gccgccgtga tcgctgccga agaacataaa gtttttcttt
     2701 ccgagacaga ctgcacgaag cgctctttcc gcggcattat tatccgcctc cgccagacca
     2761 tcatcacaga agttgcacaa cgcaacccag tgcttccgga tataccggaa cgcatctctc
     2821 agacggcatt ttttcgataa tgtgtgttct ttctcctgca tcagcttata cagggaagtc
     2881 agtagcggtt tactctgcat ttgcctgacc gccaggcgtt cagacaccgg caacccgcgt
     2941 atttcggtaa ccggctcatt taaaccgtct ggtgtgtttc ctccggctcc acaaaaataa
     3001 tgtccatcat ttttaatgga cactatcgta tggaataccg gacctggatc actgaagctt
     3061 tacgtcttca ctttgaagaa catttaccac ggattgtggc cggacgtcgc ctgggcgtac
     3121 caaaatcaac agtttgtggt atgttcgtgc gcttccgaaa agctggcctt tcatggcctc
     3181 tgcccgcagg tatgtcggag cgggaacttg atgcccgtct ttacgggagt gcctccacag
     3241 tacctgtcgt acttactgaa aacaccgtta tgtccgaagt cccggtggta aaaaaacgcc
     3301 cccggcggcc taatgccagt cagttaagca actgactggc tctttttcgg ggctgtgggg
     3361 tatttccagg gcctctcctt taccactctc gggaaggccc tttcccttat tgtcggtaat
     3421 ttcacaagtt gtcccatact tgcaagatcg cgcatcagct ccggtatatg tcccggtgaa
     3481 gcgccctgca atgtcatcag cattttcatc accattccgc atgattctga gaaactcagt
     3541 tgattcggcc agtaaccttt cagatgttcc gccattttaa tcatctgata tctcaccaga
     3601 ttataagcca gtaagacacc ccacagctct tgctccacaa gctccggctt tttacttctc
     3661 agcgtcagcc tgctcagttg catcgtctgt tttatctccc tgtatcccag ttcgattgta
     3721 agcggctcgc cagaaccgta ttgatattta ctgagaggtc agatcaactt tccagggcaa
     3781 cagatcgcgt acccggtttg ccgaccagtc ctgcatatga tctgtgacgt aatgcagcaa
     3841 tttttctgac tccgcattgt tcagacggca ggtgccgatc agtgagcaca atatgtgctg
     3901 catatttgcc gccgctgtcg gaacctgcag catattacag gttattactc gatcccgatg
     3961 gatgatattg ggggatttct ttccatgaaa atacgtaaga gtcgggagta atttgtctta
     4021 ccatcaatct tcttcatcac gcccaaagaa aaatagtcat tcaaagtacc ccgggcattt
     4081 tgcccgggga ttattactat tttaatggat tgttgatctt tgcataatca aacggactga
     4141 tacatttctc tctgttcgca ttcagaaaat ctgcccacca ctgtagcatc agccggcgtt
     4201 cttccagatg ttcggcttta tggatgtaag cagcgcgtac accgttacgt tcctgatggc
     4261 tcatctgacg ttcaacagca tcgcgggacc acaaacctga ttcgatcagc gcactacatg
     4321 ccatcgcacg gaatccatgg ccacagacat cctgggttgt gtcatacccc atcaccctca
     4381 gggctttatt tacagtattt tcactgattg gtttacacgg gtcatgtgct cccgtaaaga
     4441 tcagaccatt ttcaccagcc catgtctgta gttctgccag tatggctaca gcctgtttgc
     4501 tgagtggcac aagatgtggt gttcgcatct tggagccccg gtgtgagaat tttacgccag
     4561 gcagaggttc gcgttcggct ggaatagtcc acatggcatt gtcaatatca atttcagacc
     4621 accgggcgta tctgagttca ctggaacgaa taaaaaccag taaattcagc ataacggcaa
     4681 gccgggtgac aggctggcct ttataaccgt caatacgcga cagaagttca ggcaggcgtg
     4741 aaagattcag agcggggcga tgctggcgtt ttaccgtggt caatgcacca gccatatcca
     4801 gagccgggtt atatctgatg atgccagact gtacggcgta acgcattaca gcagatattc
     4861 tttgctgcag acgactggcg atttcataaa tttgttttgc ttctgcagca cgaacaggaa
     4921 taagcaggtc cggggtattg agtgttgtga tatcccggtt gccgataaag gggaaaacgt
     4981 gtgtctcgag gcttttgagt actttatcgc tgtgtgattg tgcccattgt ttattactgg
     5041 catgccagcg tcgtgcaata tgttcaaaag agagctgtaa atcagggaca acttttttaa
     5101 ctcttttctg ttcgcaaggg tcaatcccct ccgaaatcag ttttcgggcc tcatcccgtt
     5161 ttgtacgagc ttcggagaga gaaacttccg gatacacacc aagtgccaga gtcttctcct
     5221 tacccagaat acgataacgg agacgccagt aacgggaacc attaggatga accagcagga
     5281 acatgccagc cccgtcagtg agtttataag ccttgtcagt gggctttgca gcccggattt
     5341 ttgcgtcagt cagtgccata gtacagcctt ctgaatgcgt taaagagggt acaaattctg
     5401 tcgaactggg gtatacccgc aattataccc acacaatggg gttgatgtgg ggggaatctg
     5461 gttgagttcg gtagaattga tttgtaggta gaacgcttaa attgtggcgt tctgaaacga
     5521 aaaacggacc tccgtggagg tccgttgata tgaatttggt gcccggactc ggaatcgaac
     5581 caaggacacg gggattttca atcccctgct ctaccgactg agctatccgg gcaacggggc
     5641 gcattaaacc tgattcgcct cgtctcgtca atcaaatttc ttcaatttac tgcagactgc
     5701 acaatctatc atcactttgc cgatattgca cgcattgtca ggcaaaccag gcggtccagg
     5761 cggcggaaag cggcattgcc agaaggagtg ctggaagcat gttgaccacc gggaacattt
     5821 taatgccaca gatgcgtaat ccggttgcca gcagcaataa accgcctacg gcgctgaagt
     5881 ctgccatcat cgacggtgtg gtcagcggta aaatcagcgc ggcagcccac gccagcgtta
     5941 actggatgat cagtaatggg atactaatca ccgataccgc aatacccagc gagcaggcga
     6001 agatcatcgc cgtaaagaaa tcaagaaatg acttggcgat taaaatactc ggatcgccgg
     6061 tcatcccttc gttcatcgcc ccgaagatcc cggtgccgct ggcgcaaaac aggacaataa
     6121 tcgcgacata attctgaata aaagattcat gcgctggctt cttacgtgag tgacgaaaca
     6181 gattttgtgc tttggcgact gctgtattga cacctttctc cagcaaacca atttcgccaa
     6241 ttagagcgcc aagtagcgta gctaaaacca tcgctggaag gttggcacat ttcaccacta
     6301 gtaaaatacc aatccccagc gatgccagac caaaaataga tgtcatggag acgcggatac
     6361 gttccggtaa gcgttggctg agcagtgcgc cgagaacgcc acccagtaat actgcactag
     6421 cgttgataaa agggccgatg accacaagag ttcctgttaa ctgtattgtt tgattttctt
     6481 attatgaccg tttggtgccg tcgatggctt gtttgttcgc aaagtcctgg cttgcacgct
     6541 ttagcgaaag gtgccatgat tgcgcgaatt ttctcctctc tgtacggagt ttgcccgatg
     6601 cacgccatct ccttacattc tctcgcttat cgccgtttcg cgcgaaacgt ttccctttct
     6661 atgttactgc tcatgcggtg aagttaacgc acgctcactg caggacaaca gtaaaatcag
     6721 agcgtttctg cttttactga tgtctggcgg tcggagctgg tgaccagttt gacccatatc
     6781 tcatggggca gggttttcca ccttgtccgg tattcttact tccccgaaac gggtttgcgc
     6841 ttatgaaatc aatgaatatt gccgccagta gtgaactggt atcccgactt tcttctcatc
     6901 gtcgcgtggt ggcgttggga gatactgatt ttacggacgt cgcggcagtc gtcattaccg
     6961 ctgcggatag tcgcagtggc attcttgcgt tgcttaagcg caccggtttt catctaccgg
     7021 tgtttttgta ttccgaacat gctgttgaat tacctgcggg cgttacggcg gtaatcaacg
     7081 gcaacgagca gcagtggctg gagctggaat ccgcagcctg tcagtatgaa gagaatttgc
     7141 tgccaccgtt ttatgacacg ctgacgcagt acgttgagat gggcaacagc acctttgctt
     7201 gccctggaca tcaacatggt gcgtttttta aaaagcatcc tgccggacgc catttttacg
     7261 atttctttgg tgagaacgtc tttcgcgccg atatgtgtaa cgctgacgta aaattgggcg
     7321 atctgcttat tcatgaagga tcggcgaaag atgcgcagaa attcgcagcc aaagtctttc
     7381 atgccgataa aacctatttt gtgctgaacg gcacatcggc agcgaataaa gtggtgacga
     7441 atgcgctgtt aacgcgtggc gatctggtgc tcttcgaccg taacaaccat aagtcgaatc
     7501 atcacggcgc gctgattcag gcgggggcga cgccggtcta tctggaagct tcacgcaacc
     7561 cgtttggttt cattggcggt attgatgcgc actgttttaa tgaagagtat ctgcgccagc
     7621 aaattcgcga cgttgcgcca gaaaaagccg acctgccgcg cccgtatcgc ctggcgatta
     7681 ttcagctggg aacctatgac ggcactgtct ataacgcccg tcaggtgatc gataccgttg
     7741 ggcatctgtg tgattacatt ctgtttgatt ccgcgtgggt cggttatgaa caatttatcc
     7801 cgatgatggc ggatagctcg ccgctgctgt tagaacttaa cgaaaacgat ccggggatct
     7861 ttgtgactca gtcggtgcac aaacagcagg cgggattctc acagacgtcg cagatccata
     7921 aaaaagataa ccatatccgc ggacaggcgc gtttttgccc gcataagcgg ttgaataacg
     7981 cctttatgct ccatgcttct accagccctt tctatccgct gtttgctgca ctggatgtta
     8041 acgccaaaat tcatgaaggg gagagtgggc gtcggctgtg ggctgagtgt gttgagatag
     8101 ggattgaagc gcgcaaggct attcttgcgc gctgtaagct gttccgcccg tttatcccgc
     8161 ccgttgttga tggcaaattg tggcaggatt atccgacatc agtgttagcc agcgaccgcc
     8221 gttttttcag ttttgagccg ggggcgaagt ggcacggctt tgaaggatat gccgcggatc
     8281 agtattttgt tgatccgtgc aagctgttac tcactacacc aggtatcgat gccgaaaccg
     8341 gcgaatatag cgactttggc gttccggcga cgattctggc gcactatctg cgtgagaacg
     8401 gcattgtgcc ggagaagtgc gatctcaact ccattctgtt tttattaact ccggcggaaa
     8461 gccacgagaa gctggcacaa ctggtggcga tgctggcgca atttgaacag catattgagg
     8521 atgactcgcc gctggttgag gtgttgccga gcgtttataa caagtatccg gtgcgctatc
     8581 gcgactacac cctgcgccag ttgtgtcagg agatgcacga tctgtatgtc agtttcgacg
     8641 tcaaagacct acaaaaagcg atgttccgcc agcagagttt cccgtcagtg gtgatgaacc
     8701 cccaggatgc gcatagcgct tatattcgcg gtgacgtgga gttggtgcgg attcgtgatg
     8761 ccgaagggcg aattgcggca gaaggggcgt tgccttatcc acctggcgtg ctttgcgtgg
     8821 tacccgggga agtctggggt ggggcggttc aacgttattt ccttgcactg gaagaagggg
     8881 tgaatttgtt gccgggattt tcgccggagc tgcaaggtgt ttatagcgaa accgatgcgg
     8941 atggcatgaa acggttgtac ggttatgtgt tgaagtaaga ataaaaaaaa cgggtcacct
     9001 tctggcgacc cgtttttctt tgcgtaatta gtggctaacc gtctgtgtgc ctgtcgggac
     9061 acgaacgtgt ttatatttga acatcgccat gaacgcgaag gccagaacca cggagtaacc
     9121 agcgaaaatc aaccatacgg tctgccagtc ggtaatgccg ttttgggtgt acatctcaac
     9181 aactctaccg ctcacgatgc cgccgaggat acagccgaag ccgttagtca tcatcaggaa
     9241 catcccttgt gcactggcgc gaattgccgg gctaacttct ttttcgacaa acaccgaacc
     9301 agagatgttg aagaagtcga atgcgcaacc gtaaacgatc atcgacagta ccagcagtac
     9361 agtaccgaac ggagtcgggt cgccgtaagc aaacagcgca aaacgcagga tccacgccac
     9421 aatactgatc atcattacgt tcttaatacc gtagcggctt aagaagaacg ggatggtcag
     9481 aatgaacagg gtttcagaga tctgcgaaat cgacatgatg attgacgcat gctgcacaat
     9541 aaagctgctg gcaaacatcg gatctttgtc gaagctgtgc aggaaggtat taccgaacat
     9601 gttggtaatc tgcagttccg cgcccagcag cattgagaag ataaagaaga ttgccatacg
     9661 cttgttttta aacagcgcga atgcatcgag gcccagcagg gttgtccagc tctgattcgc
     9721 ttgctgttta gcaaccggaa tatgcggcag agtcagggta aacagaacca gaatggcgga
     9781 aagtgctgcg ccaatataca gctgcatgtg gcttaattcg aagccagaca ggctcaccac
     9841 ccacattgcc atgataaagc cgatggtgcc ccagatacgg attggcggga agtcagtaac
     9901 gatatccatc ccggcatttt gcaggcgata gtaagagatg gtgttgatta acccaagcgt
     9961 tggcatataa gcaaacgagt taatcaatat cacaaggaac atcgcctccg gtgtcgtgac
    10021 ctgtgccgcc atgaacagcg tgatagcgcc aatggtgtgg caaatggcat atacccattt
    10081 cgcacttaac catttgtcgg ccacaatccc cagcagcgca ggcataaaga ccgctgcgat
    10141 acccagtgag ctataaactg cgccaataga agcaccgtca aacttcaggg taacaaacat
    10201 ataggagccg agggtcgtca gccaacttcc ccacagacag aactgcagaa aagagaggat
    10261 tttcagctgc agcttaagat tcatgttaat ttcctcacat cgtgatgcgg atgagtgttt
    10321 gaaaaagcac atttgaccgt gcgagatgat gggattctat caacttcgcg gactggtttt
    10381 ttgttacctg tggcaaataa ttgcaaacat tcccaatttg caaaacgaaa ttgtgatgtg
    10441 gataacattt ttgcccctga gcatcgtcag gggcggttaa tggaattatc ggcggcggta
    10501 ggatttttgc gcggtattca ctttataaag ataacggcga gattccgcag agggatggcg
    10561 ggtcgtcagc gtctgataaa catcgcccgg cgtcatggtg ttaataatat tggcagcctg
    10621 aatcttatca ttcgaaaaga ctcgcagcac gctgcctgcg ccgccgttat aggcggtgat
    10681 gacggcataa cgccgcgatg ttgggttatc aattccgccg agataaacat tgttcagcat
    10741 cgccagatac gcggtgccgg tatcaatatt gctggcagga tcaaacaaga aactgcggct
    10801 cggcgtgccg gatttcccct gcgagcggaa cacatctttc ccggcagtat gttgtaccac
    10861 ctgcattaat cccagcgcat cggaacggct gaccgcatac gggttaaagg aagattcggt
    10921 ctgcataatt gccagaatca gcgactcatc aacgccatat ttccgtgacg cctggcggac
    10981 catgccgaga tatttgtgcg cacgtttatc aaggtggttc ggcaccatgt taatggtgac
    11041 gctgtagatg atacgcagcc cgttgctgcg gctcttcaga cggtttttca gcagataatc
    11101 cgcgaagttg cttgcgcgac cttcccagcg aatcggctgc ccggtgttgt ccaccacctg
    11161 accgtaaagg aaaggttctt tcgaaatcgt aatatcatca acgtcggaat agagatcgac
    11221 cgaactcgga tcgtcaccca tcaataacgt tttgataatt gcccggcgca aatgcgcggc
    11281 aggttctgtc ccggcgatgg tttcgatagt aatcgtaccg tcatcgaagt tgatgtggct
    11341 gcgggtctga tattgatcgg tgtatttcac gtagtcctta ggaccagcga tcaccacctc
    11401 tttgaagccc cagatgttct caatattgtg ggcaaattgc cccatcagaa tatcaaaacc
    11461 gttggtatct ttgacccagg cttcgttata ggtatcgcct tttttggtcg tcgaacagga
    11521 gatgagcaac ggcgcaatca aagccagcgc gagatatttt ttcatcattc cgggtgcgtg
    11581 ttgtgtttgt ttttatgcaa gttgccggag gcgtgctccg gcactgtttt tattttttat
    11641 cttccggcgt atagccctcg atatgcacct ctttaccctc gaacaggaag ttgaccatct
    11701 cctgctcaag cagcttgcgg tgctcggcat tcatcatgtt gagtttcttt tcattaatca
    11761 gcatggtttg cttgtgctgc cactgcgccc aggcttcttt ggagatctcg ttatagatgc
    11821 gttttcccag ctcgccgggg tacagctgaa aatcctgacc ttctgcttca cgttgcagga
    11881 aagtacaaaa aatcgttctg ctcataaatc atcctcttta tcgactcacg cgctaaaccg
    11941 gcgcgccagt gcgtaactgc tgtaacaaac gctccacggg agccgccagg ccaactgacg
    12001 gcggttgcgc taagttatac cagagcgcat tgccttcatc catgcagccg gtgaatgacg
    12061 acacgggaag ccacataggc acaatatcta agtggaaatg gctgaaggta tgccgaaacg
    12121 cggtcagttg cgtcaggtta tcggcagcaa tctgccgttg cgccagccac tgccgcaaac
    12181 tttcttcgtc ggcaaactgc gggaaacagt ataaaccgcc ccacaatccg ctcggcggac
    12241 gctgcgccag caatacttca tcttcgtgct gtaatagcaa aaagtagccg gtgcgctccg
    12301 gcagcgtctg tttcggtttt ttgcccggat aaagcgccca gctattgttg gcggcggcaa
    12361 tacatccgtt ttgtagcgga cagagcgaac atttcggttt cgagcgcgta caaatcatcg
    12421 cacccaaatc catcatcgcc tgattaaacc gttccacgcc aaccgcgggc gtcacctgct
    12481 cgctcaaact ccataattta ttctcgacct cttttttccc tggccagccg cttacagcat
    12541 agcagcgcgc cagcacccgt ttgacgttac cgtcgagaat cggaaagtgc ttacccagag
    12601 aaagcgagag aatcgcgcct gcggtggaac gcccgacgcc cggcagtgct gcaacttcct
    12661 caaaggtttc cgggaattta ccgccgtgta aggtcgccac ttgttgtgcc gctttatgca
    12721 gattgcgcgc gcgggcgtaa tagccaagcc cggtccacaa gtggagaact tcgtcgagcg
    12781 gcgcattggc gagatcggtc accgtcggga agcgcgccat aaagcgttca aaatagggga
    12841 taacggtcgc aacctgagtt tgttgcaaca tcacttctga gagccatact ttgtagggcg
    12901 tcttgtcaat ttgccagggc agagtttttc gcccgtattt atcgtaccag tccagaacct
    12961 gggctgaaaa ttgcgacgct tgcatggtca ccgaattcac tgttgttggg ggcaagattg
    13021 cagcacagcg acggcagggt gtaaaccgga actttccgca gccacggcct tatcatgctt
    13081 gcatccggca actaactttg gataatgccc gttttcagaa cactttcaca agcgactaaa
    13141 cctttatgaa aaacgacgtc atttcaccgg aatttgatga aaacggccgc ccactgcgcc
    13201 gtatccgtag ttttgtgcgc cgccaggggc gactgaccaa aggccaggaa catgcgctgg
    13261 aaaactactg gccggtgatg ggcgttgagt tcagcgaaga tatgctggat ttccccgcgc
    13321 tttttggccg tgaagcgccg gtgacgcttg agattggttt tggcatgggg gcgtcgctgg
    13381 tggcaatggc taaagatcgc cctgagcagg acttcctcgg cattgaagtg cattcaccgg
    13441 gcgttggtgc gtgcctggct tctgcgcatg aagaaggttt aagcaacctg cgcgtgatgt
    13501 gtcacgatgc ggttgaagtg ctgcataaaa tgattcctga caattcattg cgcatggtgc
    13561 agctcttttt ccctgacccg tggcacaaag cgcgccataa taaacgccgt atcgttcagg
    13621 tgccgtttgc cgaactggta aaaagcaaac tgcagctggg gggcgtattc catatggcga
    13681 ccgactggga accttatgcg gaacatatgc ttgaagtgat gtcttctatt gacggttata
    13741 aaaacctgtc agagagcaat gattacgtac cgcgtccggc atcacgtccg gtgacgaaat
    13801 ttgaacaacg tggtcatcgt cttggtcacg gagtatggga cttaatgttc gagagggtga
    13861 aataatggca aagaaccgta gccgtcgtct gcgtaaaaaa atgcacatcg acgaattcca
    13921 ggaattagga ttttcggtgg catggcgatt cccggaaggt acatcggaag aacagattga
    13981 taaaaccgtt gatgatttta ttaacgaggt tatcgaaccg aacaaactgg cctttgacgg
    14041 cagcggttat ctggcctggg aaggtctgat ctgcatgcag gaaatcggca aatgcaccga
    14101 agaacatcag gcgattgtgc gtaagtggct ggaagagcgc aaactggatg aggtacgcac
    14161 cagcgaactt ttcgacgttt ggtgggacta agaaagcata cgggcgatga caaatgcaaa
    14221 actgcctgat gcgctacgct tatcaggcct ggaaagatgc acgatcgagt aggcgggata
    14281 aggtgtttac gccgcatccg gcatggaaaa cgcgtacttt gttatcaatc tggggccagc
    14341 aaatgctggc ctgatttttt cttgagggaa gactatgatg cgcaaaatgc tgctggcggc
    14401 agcactttca gtgacggcaa tgaccgctca cgccgactac cagtgcagcg tcacgccgcg
    14461 tgacgatgtg attgtcagcc cgcaaaccgt gcaggtgaag ggcgaaaacg gcaatctggt
    14521 gatcacgcca gacggcaacg tgatgtataa cggtaagcaa tattccctga atgccgccca
    14581 gcgcgagcag gcgaaggatt atcaggctga actacgcagc acgctgccgt ggattgatga
    14641 aggcgcgaaa agccgcgtcg agaaagcccg tattgctctg gataaaatta tcgttcagga
    14701 gatgggcgaa agcagcaaaa tgcgcagccg tctgaccaaa cttgatgcgc agctgaaaga
    14761 gcagatgaac cgcattattg aaacgcgcag cgatggcctg acgtttcact ataaagccat
    14821 tgatcaggtt cgcgccgaag gccagcaatt agtgaatcag gcaatgggtg gaattttaca
    14881 ggacagcatt aatgaaatgg gcgcgaaagc ggtgctgaaa agcggcggta acccattaca
    14941 gaatgtgctg ggaagcctgg gggggctgca atcctcaatc caaaccgagt ggaaaaagca
    15001 ggaaaaagat ttccagcagt ttggcaaaga tgtttgtagc cgcgttgtga ctctggaaga
    15061 tagccgcaaa gccctggtcg ggaatttaaa ataatcctct attttaagac ggcataatac
    15121 ttttttatgc cgtttaattc ttcgttttgt tacctgcctc taactttgta gatctccaaa
    15181 atatattcac gttgtaaatt gtttaacgtc aaatttccca tacagagcta agggataatg
    15241 cgtagcgttc acgtaactgg aggaatgaaa tggagttttt caaaaagacg gcacttgccg
    15301 cactggttat gggttttagt ggtgcagcat tggcattacc caatatcacc atttttgcaa
    15361 ccggcgggac cattgccggt ggtggtgact ccgcaaccaa atctaactac acagcgggta
    15421 aagttggcgt agaaaatctg gttaatgcgg tgccgcaact aaaagacatt gcgaacgtta
    15481 aaggcgagca ggtagtgaat atcggctccc aggacatgaa cgataatgtc tggctgacac
    15541 tggcgaaaaa aattaacacc gactgcgata agaccgacgg cttcgtcatt acccacggta
    15601 ccgacacgat ggaagaaact gcttacttcc tcgacctgac ggtgaaatgc gacaaaccgg
    15661 tggtgatggt cggcgcaatg cgtccgtcca cgtctatgag cgcagacggt ccattcaacc
    15721 tgtataacgc ggtagtgacc gcagctgata aagcctccgc caaccgtggc gtgctggtag
    15781 tgatgaatga caccgtgctt gatggccgtg acgtcaccaa aaccaacacc accgacgtag
    15841 cgaccttcaa gtctgttaac tacggtcctc tgggttacat tcacaacggt aagattgact
    15901 accagcgtac cccggcacgt aagcatacca gcgacacgcc attcgatgtc tctaagctga
    15961 atgaactgcc gaaagtcggc attgtttata actacgctaa cgcatccgat cttccggcta
    16021 aagcactggt agatgcgggc tatgatggca tcgttagcgc tggtgtgggt aacggcaacc
    16081 tgtataaatc tgtgttcgac acgctggcga ccgccgcgaa aaccggtact gcagtcgtgc
    16141 gttcttcccg cgtaccgacg ggcgctacca ctcaggatgc cgaagtggat gatgcgaaat
    16201 acggcttcgt cgcctctggc acgctgaacc cgcaaaaagc gcgcgttctg ctgcaactgg
    16261 ctctgacgca aaccaaagat ccgcagcaga tccagcagat cttcaatcag tactaatcgc
    16321 ctcgccccgg tatcgtgccg gggctttttc acttcagact cacgtccatt gccaatttta
    16381 attaccctaa tgataatcac cggaataaat tattctgcgc gagggttttc gggtgaaaaa
    16441 gcaatggatt gttggcacgg cgctgcttat gttgatgaca ggtaatgtct gggcagatgg
    16501 cgaaccacca actgaaaata tcttaaaaga tcaattcaaa aagcagtatc acggcattct
    16561 caagcttgat gctatcacct taaaaaatct tgatgctaag ggtaatcagg ccacctggtc
    16621 agcggaaggc gatgtctctt ccagtgacga tctctatacc tgggtcggtc agttggcaga
    16681 ttacgaactg ctcgaacaga cctggacgaa agataaaccg gtaaaattct cggcgatgtt
    16741 aaccagtaaa ggaacgcccg cgtctggctg gtcggtgaac ttttactctt ttcaggcggc
    16801 agccagcgat cgtgggcggg tggtcgacga tatcaaaacg aataataaat atctgatcgt
    16861 gaatagcgaa gatttcaatt atcgctttag tcagcttgaa tctgcgttga atacccagaa
    16921 gaactcgatt cctgcgctgg aaaaggaagt gaaagcgctt gataagcaaa tggtggcggc
    16981 gcagaaagca gcggatgcat attggggaaa agatgcaaac ggtaagcaaa tgacccgcga
    17041 agacgccttt aaaaaaattc accaacagcg tgatgagttt aataaacaga acgatagcga
    17101 ggcgttcgcg gttaaatatg acaaagaggt ttatcaaccg gcgattgcgg catgtcataa
    17161 acagagtgaa gagtgttatg aagtgccgat tcagcagaaa cgagatttcg atatcaacga
    17221 acaacggcga cagacttttc tgcaatcaca aaaacttagc cgtaaattgc aggatgactg
    17281 ggtaacgctc gaaaaagggc aatatccgtt aacgatgaaa gtttcagaaa taaacagtaa
    17341 aaaagtcgcg attttgatga aaattgacga tatcaaccaa gctaatgaac gctggaaaaa
    17401 agataccgaa caactgcggc gcaatggggt gattaagtaa gtttgatata gtgcacgatt
    17461 tgtagcagga tgcggcgttg accccgcatc cggcaatcaa cgtctgatgc gacgcttgcg
    17521 cgtcttatca gacctacaac cgctgccaca tgtcggctgg ataaggcgtt cacgccgcat
    17581 ccggcaatac aagtttactc agccagaaaa agctccagca gcgaatttaa aaacagcttc
    17641 ccatgttccg ttatctgcca gtaatccgca cattcggtga gataaccctg ggcaatcgcc
    17701 tcgtctaact gtgggcgaat cacatcttcg caaagcccgg tatacgcaat aaactccacg
    17761 cgcggcgcgg cctccagcag acggaagcga ttcataaaga actcaaacgg cttatctgtg
    17821 gcttcgacat cacgctggct ttccagatac cttccttgca taaaaccacg cggatgacgc
    17881 gttttggtgg tacgcagaat gcgcccatcc gggaaggtca ctttgccgtg tgcgccgcag
    17941 ccaataccga tgtagtcacc aaagcgccag tagttgagat tgtgctggca ctgataaccg
    18001 ggtttggcgt aagcggaagt ttcatattgc tgataacccg ctgcggttaa taactgatgc
    18061 ccctgttcga atatatccca caacgcgtca tcgtccggca gcaccggtgg tcgcgaacca
    18121 aacagcgtat tgggttcgat ggtcagttga taccaggaaa gatgcggcgg attcagttca
    18181 atggcctggc gtagatcgcc aagcgcctct tccagtgatt gatccggcag cccatgcatc
    18241 aaatcaaggt taaagctacg taaccctaaa ccgctcgcca gcttcgccgc gcgtttcgct
    18301 tcttgcgggc catgaatacg cccaagtcgt ttcagctttt cttcgctaaa actctgcaca
    18361 ccaatagaga tgcggttcac accagcacgc tgataatcga caaagcgatc ggcttctacc
    18421 gtgccagggt tcgcttccat agtaatttct gcatccgctg ccagcggcaa acgcgcacgc
    18481 acgccgtcca gcagcgtttg catcgccggg ccggaaagca ggctcggcgt accaccgcca
    18541 ataaagattg tctttacttc acggccctga gcgtaagcca catcgttgtc cagatcgtta
    18601 agcagatgct gaacataatc gtcgtgcggc acttctcctt tcaacgcgtg agagttgaaa
    18661 tcgcagtacg ggcatttctg cacgcaccac gggatgtgaa tgtagagact cagcggaggt
    18721 aatttaacca ttacgtaaag cgtccagcag cagtttcaac gcctgaccac ggtgggaaat
    18781 ggcgctcttt tcttcgcggg tcagttcggc ggcggttttc ccttcggaag gtacgaagaa
    18841 gattggatca taaccaaagc caccagtgcc cgctggttca cgagtaatca cgcccggcca
    18901 gctaccgtgg cataccagcg gagtgggatc ttccgcgtga cgcagatata ccagcacgca
    18961 gtggaaacgc gcctgacgtt ggtcgtccgg tacgtctttc attgtttcca gcagtttttg
    19021 cagattcttt tgatcggtcg cgtcttcacc ggaataacgc gcggagtaaa tgcccggcgc
    19081 gccgccaagc acatctaccg ccagaccaga gtcgtcggca attgccggta aagcggtcac
    19141 ttttgccgca tggcgcgctt tcagaatcgc gttttcgata aaggtcaggc cggtttcttc
    19201 agcggaatca acgccgaggt ctgtttgggc cacgatatca agaccgaagt cgctaagcag
    19261 cgacgccagc tcacgcactt taccgacatt gccggttgcg aggacaactt tttgcatagg
    19321 atacctaatt aattaacgcc gcgatttctg gcgggatttg ttgcggatta atgattttaa
    19381 tttgtttgtg gcggccaagt tcgccttttt caatcaccac ctggcttttg gcaacccgga
    19441 attgcttacc gagaaacttc accagatgac tgttggcctg gccgtcaacc ggcggcgcgg
    19501 taatggcgac tttaacttcg tcgccatgta aaccgacaat agaatcacgg ctggctttcg
    19561 gctgaatata gagccgtaaa accagaccgt catcattaac tgttacggca ttcataacgc
    19621 catccacagc cctggcagca gcatatttcc ggttgcctgt aatacttctg cgacacccat
    19681 attgatgaca tacagcagca gaacgaggat catcggcgag aaatcaatcc cacccattgc
    19741 cggtagcagg cggcgaatcg ggcgcagcag cggatcggcc agctgaatca gcacgtattc
    19801 aatcgggcta cgcccctggc ttacccagct cataatcgcc atcaccagca ggacccagaa
    19861 aatcagcagg ccgatggttt tcagcagaat cagtaaaccg gcaatccaga tgattggcag
    19921 gaaggtcacc actttaaaca gcacgatggc tttgataaaa ctgagaatat aggcaaccag
    19981 cagcgaggcg ctgtcaattg gccccattgc cggaataacg cggcgcagtg gcccgataat
    20041 tggctgcgtt accttcacta caaactgtga gaaggggttg taaaaatcac aatgagccca
    20101 ctgcatccag atgcgtaata acagcaccat ggtatacagc tcaatgaccg ttgaaagcag
    20161 gaaagtcaac gtattcatgg cgttccttta attccttatt ttttagagta atcacgcgca
    20221 ccaaaaattg cagtgccgat acgaaccatc gtgctacctg ccgcaatggc ggcttccata
    20281 tcgtccgaca ttcccagaga gagcgtgtcg atatgcgggt agcgcgtttt cagtccggca
    20341 aatgctacag ccatttggcg tgcaacttca aactgcctta catattctga ctcaggcgca
    20401 gggattgcca tcaacccgcg cagacgtaaa cgcggtagtt cagcgaccgc agctgccagc
    20461 tcgtccagtt cagccagttg aatcccggac ttactgtttt catcactaat gttaatttga
    20521 atcagaacgt taagaggggg aagttctgcc gggcgctggt cgttgagacg ggtagcgatg
    20581 cgcaaacggt cgatggtatg acaccagtcg aaatgctctg ccaccaggcg gcttttatta
    20641 gactgcaacg ggccaataaa atgccattct aatcctgtta cgcccagttc ctgaaagtgg
    20701 cgaattttat ctaccccttc ctgaacgtag ttttcaccaa attgacgctg cccggcatca
    20761 atggcttctg cgatggcgct cgcaggtttt gttttactga ctgcaagcag cgtaatttct
    20821 tctggagaac ggccgcaacg cgttgcagcc gctgagattt tgtcccggac ctgtgccagg
    20881 ttatgcgcaa tatcgttcat tttccgagga tcttagtatg aatatggaag aaattgtggc
    20941 ccttagtgta aagcataacg tctcggatct acacctgtgc agcgcctggc ccgcacgatg
    21001 gcgcattcgc ggcagaatgg aagctgcgcc gtttgatacg ccggacgtcg aagagctact
    21061 gcgggagtgg ctggatgacg atcagcgggc aatattgctg gagaatggtc agctggattt
    21121 tgccgtgtcg ctggcggaaa accagcgatt gcgtggcagc gcattcgcgc aacggcatgg
    21181 catttcgctg gcgttacggc tgttaccttc gcactgcccg cagctcgaac agcttggcgc
    21241 accaacggta ttgccggaat tactcaagag cgagaatggc ctgattctgg tgacgggggc
    21301 gacggggagt ggcaaatcta ccacgctggc ggcgatggtt ggctatctca atcaacatgc
    21361 cgatgcgcat attctgacgc tggaagatcc tgttgaatat ctctatgcca gccagcgatg
    21421 tttgatccag cagcgggaaa ttggtttgca ctgtatgacg ttcgcatcgg gattgcgggc
    21481 cgcattgcgg gaagatcctg atgtgatttt gctcggagag ctgcgtgaca gcgagacaat
    21541 ccgtctggca ctgacggcgg cagaaaccgg gcatttggtg ctggcaacat tacatacgcg
    21601 tggtgccgcg caggcagttg agcgactggt ggattcattt ccggcgcagg aaaaagaccc
    21661 cgtgcgtaat caactggcag gtagtttacg ggcagtgctg tcacaaaagc tggaagtgga
    21721 taaacaggaa ggacgcgtgg cgctatttga attgctgatt aacacacccg cggtggggaa
    21781 tttgattcgc gaagggaaaa cccaccagtt accgcatgtt attcaaaccg ggcagcaggt
    21841 ggggatgata acgtttcagc agagttatca gcaccgggtg ggggaagggc gtttgtgacg
    21901 ttgccatgcc cgatgcgcaa gcttatcggg cctacaaagg caataaatgt ctgatgcgac
    21961 gctaacgcgt cttatcagac ctatagccgc tgccagatgt gtgctggata aggtgttcac
    22021 gccgcatccg gcaataagac gcgatgatat tatttacact ccgccaggcg tttaaatcgc
    22081 cttaatatcc ctgctcgaaa tagctttcga gaataataac cgcagaggca gagtcaactt
    22141 tgcctttgtt gagcgcccga tagccgccct gttcaaacag accggaacgg gcttccacag
    22201 tgctaagacg ctcgtcatgg agctttactt caacaccgaa acggccatga atacggttgg
    22261 caaatttacg cgctctggca gtcaatggtt gctcggtgcc gtccatattc agcggcaaac
    22321 cgacgatgat ttcgtccggc tgccactctt tcagtaaacg ctcgataatg ttccagtccg
    22381 gcgtaccgtc ctgtgcttta attgcaggca aagggcgagc ggtgccggta atgcgttggc
    22441 cgaccgctac gccaatgctt ttggtgccga agtcgaaggc gagtaaggtt ccactcatca
    22501 ggcgtgtcct gccacaccag gcatggtgag aatatccaca ccaatcagtt ttgccgcctc
    22561 gcgccagcgg tcggcaatcg gcgttttgaa cagaatattc agatctgccg gggccgttag
    22621 ccacgcgtta tcgagaattt cttgttccag ttgacctttc tcccaggagg cataacccag
    22681 agccaccaat acgtcagacg gttgtttatc ggtgccgagc gtttccagca catcgcggga
    22741 agtggtcatt accgtgttgt ctgaaatgcg aatgctggaa gcaaaattgg agggcggagt
    22801 atgcaaaata aacccgcgat cttcagccag cggaccgccg agcataaccg gtttatccag
    22861 acggattgat tcatcacgcg gctccggcgt gatcttcagc ttttccagaa tcccttcaat
    22921 tttgagattt tccagcggct tgttgacgat gatccccatt gcaccattgg tattatgttc
    22981 gcaaatgtag accacggaac gacggaaaat cggatcctgg agagcaggca tggcaataag
    23041 aaagtgatgc tgtaaattca ttgtcagagg ttctgtttcc tggttcaaaa aagcaacagc
    23101 gcccagtatg cgtggaaaga agggcgctgt cactcagagt ctcaacgaga tccttctcgc
    23161 taaggtgggt tactgctgct gtaaacgtgc ttcgatggca tccattaaca ttccggtgat
    23221 cgacaccgga aactctgctt caatctcacg aatacaggtt gggctggtga cgttaatttc
    23281 agtcagacgg tcgccgatga tatccagacc aacaaaaatc agcccttttt ctttcagcgt
    23341 cggcccgatc tgacgggcga ttttccagtc actttccgtc agcggacgag gttcaccgcg
    23401 accaccggca gccagattgc cacgggtttc gcccccctgc ggaatacgcg ccaggcagta
    23461 cggtaccggc tcgccatcca ccaccagcac gcgtttgtcg ccatctttaa tggctggcag
    23521 gtaattttgc gccatgcagt agcgagtgcc atgctcagtc agggtttcgg caatcacgcc
    23581 gaggtttgga tcgccttctt tcacgcggaa aatcgacgcg ccgcccatac cgtccagcgg
    23641 cttaagaatg atgtcgctgt gtttctccca gaacgctttt agctgcgctt tattgcgcgt
    23701 aaccagcgtt tctggcgtta agtcagagaa ccaggcggta aacagtttct cgttacagtc
    23761 gcgcaggctc tgcggcttgt taacgatcag cgtccctttc tcttcggcac gttccagaat
    23821 ataggtcgcg tagataaact cggtatcaaa cggcgggtct ttacgcatca ggatcacatc
    23881 gagatcggcc agcggcagat cctgttcacc gacgaacgaa aaccactctt cgtagttctg
    23941 cttcacgttc agcgtgcggg tatgggcgcg ggcttcacca ttgatcagat acagatcgcc
    24001 catctccata tagtgaagtt cgtaaccacg acgctgtgct tccagcaaca tagcaaaact
    24061 ggaatctttc ttgatgttga tgtttgcgat ggggtccatc acgatgccga gcttgatcat
    24121 tattcttctc cgttagccca aatcgccaaa tcgtacttgt agcgcggtaa tggcggtgag
    24181 cgcagttgtc tctgtacgca aaacgcgagg tcccaacagg atatcagtaa attgatagcg
    24241 ggcagtcatg gcaatttcat ctgccgataa accgccttcc gggccaatca gcaggcggac
    24301 gcgttcaacc ggtaacggca acgtattgat gctgttactg gcgcgcgggt gaagattcag
    24361 tttcagtcct tcatcctgct ctgcacacca ggcttccaga tccatcgctg gacggatttc
    24421 cggcacccgg ttacgaccac actgctcaca ggcagcaatt gcaatcttct gccactgctg
    24481 aagcttcttg ttcagacgtt cactatccag tttaacgccg cagcgctcag aaaaaagtgg
    24541 cgtaatgagg cttacaccga gttcgatcga tttctggata gtaaattcca ttttttcacc
    24601 acgcgacatc acctgaccga ggtgaatatg cagcggagat tcgcgatcgt cgatctggcc
    24661 ttccagcacc ttcacttcca cgcttttttt gctggcgctg gtaatttcgg cgtcaaagac
    24721 ctggttgcta ccgtcaaaca attgcaacgc ctgccccggc cccatgcgca gtacgcgccc
    24781 gatatggttg gcggcatctt cgcaaagcgc gatgtgagaa tggctggtca gtggttcagg
    24841 atgataaatg cgggggatac gcatagttaa aaatccgcgt cgtctcccca cgcggttgta
    24901 cgcgtggggt aggggttaac aaaaagaatc ccgctagtgt aggttagctc tttcgcgcct
    24961 ggcaagcgcg ttgcacatac gggttatgat tgccctgcac cttcgcgatg cgttcatcgc
    25021 gctcgcactc ccagtcggta accggataca tcttgttcca tgcgttgaac agctgcgttt
    25081 gctggcgaga gagtgtcagg ttgtattggt cgcgcatata gaagtaggtg cgcgcaatgg
    25141 caccgcgtgc acgcgctggt ggttcggcag ctttttcttt gaaatcgacc ttcatggcgc
    25201 attgaccgta ctggccttca ccgccattcc actggctgta cataaagttg ccgcgatcgc
    25261 cattcacctc accgactgac ggctgcaggt tatgcatatc gctttccatc ttgcgataga
    25321 ccggatcttt agcgcagttt ttacgtccac cgtcctgcca gcactggcgc tggtgaccga
    25381 actgccaggc gggaacgaca tgttcccact ctacgcggct ggcgcggttt tcatttttgc
    25441 gcacctgata gccgcacgat tgcagatcaa caacgccttt tttgccctgc cagttaattt
    25501 tacatccgca ataaaacgta ccgggcgcgt cagcgtggac ttttaccgcc gcggctttcg
    25561 cctgagaaaa actattgata ccttcggcca acgccgggcc ggaaaatgct gcgctcagta
    25621 ccaccgcagc aatagacaaa taacggtaca tcacttactc cgtgttaaaa cgagccagca
    25681 acgtagcgaa agctgttttg gtatgcaatc agccagatca ggaaagttcc tgatagttca
    25741 gatggttatt tcgcaaccag ctgttcaccg cagtgaacac agcgatagac ggcctcgcca
    25801 cgaactacgc gattatggcg gcgtacggta agctgatgct cctggcactt gcagcggtag
    25861 gggaaggtgt tgcgacgcac ggattgcagt tcgaactgat gcgtacgacg ggcgggaaca
    25921 cccagcacgt tttccatcat ccacttccac tctttgccat gtggcgctac gcggccgaaa
    25981 tgtttccata ccagcaaatg tgccagttcg tgcggtacca cttcttcaat aaaagcttca
    26041 ctgttttcca acagcaaaac gggattgagg cgaatttcat agctttccag ccaggccgtt
    26101 ccggcggagg ttccgcgctg ggtgtaagag agttttggct ccgggtagtt acgccctagc
    26161 ttcaggttgg cctgggcgag tttttcccgc aggcgacgca taacggcctg ttggatggcg
    26221 atagggagac gggatgtttt catagcggca gaggatagag cgaagaaaag atgactgcaa
    26281 gaggtggctt cctccgcgat gggaggaagc ttggggagat taatcgtgag cgcctatttc
    26341 gcgcagttta cgacctttca tcagattacg ttcaatatgt tccagcgaaa cgtgtttggt
    26401 ttccggtacc agccacaatg tcagcaggat aaacagtacg ttcagagccg catacaccca
    26461 gaaggtgttg gcgttaccca gcgtgttgag catggtcagg aacgttgcgc caacgatcat
    26521 gttggcaatc cagttggtgg cagtggagca ggtgatgcca aaatcgcggc ctttcagcgg
    26581 ctgaatttcg gagcacagta cccaaatcag cggaccggca ctcatggcaa aaccgacaat
    26641 aaacatcagc agcatggcga tggcgaaata ctgcgccgac ggagagtgaa taccgatatg
    26701 catcattgta ccgagtacgc ccatgccagc agccatcacc aggaagccca gcgttagcgt
    26761 tggtttacgt ccccagcggt caacaaggcc gattgcgata aaggtggcaa gtacgttggt
    26821 caggccgaca atcacggtcc cccacatttg ctcggtagtg ttggtataac ccgccagttc
    26881 gaagattttc ggcgcgtaat acatgatgac gttcatcccg gtgaattgct gcattacctg
    26941 caacagtacg ccaaggaaca ccgcgcggcg gaagttgctg ttctctttaa acagcgccca
    27001 gccactctgt ttaacctgca aactttcacg gatttcatcc agttcgcgtt tcgcttccgc
    27061 gctggtgtca cgcaggcgta gcagcacgcg ttcggcatca acaaaacggc gtttggcggc
    27121 aaaccaacgt gggctgtctg gcaggaagaa gacaccaatc agcagcaaaa ttgccgggat
    27181 gataatcaca cccagcatcc agcgccatgc accggtgtag ctgaaggcgg tatcagaaag
    27241 ataagcaccg aggatcccga tagtgatcat caactgatac atcgagatca tactgccacg
    27301 aattttttcc ggcgcaattt cagagaggta cagcggtgcg gtataagagg ccacacccac
    27361 cgccagcccc agtagaacgc gggaaagaat cagtacttca acgtttggcg cagccgcaga
    27421 gaacagcgaa ccggcaacaa acaaaattgc gccgatcatc aggctctttt tgcgcccgag
    27481 tttaaaggag agccagccgc tgcccaccgc accgactgcc gcaccgaaca tcatggagct
    27541 tacgacccat tcttgcgtgt gcgaagtaat ctggaattca tctgcaataa acggcagtgc
    27601 gccagcaatt acaccgatat ccaggccaaa gagtaatccc gccagagcgg caaggaagca
    27661 gacgaaaaac gtcattgcct tgtttgaccg cccctgtttt ttagcgtcag gcatgatgcc
    27721 ctccaatatg gttatttttt attgtgaatt aagataggtg agtacgacgt aaaaagatgt
    27781 gaagcaaatc acatcagtgt aatcgcttac actaacattt atcttagtta tgatttaagt
    27841 gcatgaaaat aattgagtta tatcatcata gattaaacgc tgttatctgc aattaagact
    27901 ttactgaaaa gaaatgtaac aactgtgaaa accgaataat aatatgaaaa tattacaaat
    27961 ctttgtctgt tgtggttggt gtaatcggtt tcagttgtga tgataatctg cggtgaaacg
    28021 tgatcaggaa gaatgatgtt attgtgcggg cggttttttt gccggatgcg gcgtgaacgc
    28081 ctatccaaaa gaaaaaggcc agcgcgaggc tggcctttga acgcaggtga agaaagatta
    28141 cttcagaccg gcagcatcgc gcagcagctg cgctttgtcg gttttttccc acgggaaatg
    28201 ttcacgacca aagtgaccgt atgctgcggt ttctttgtag atcgggtgca gcagatccag
    28261 catctgaatc agaccgtatg ggcgcaggtc gaagaactca cgtaccagca gggtcagttg
    28321 ttcagaaggc actttctcag taccgaaagt ttctaccatg atggaggtcg gttcagccac
    28381 gccgattgcg taggaaacct gaatttcaca acgatcggcc aggccagcag caacgatgtt
    28441 tttcgcgaca taacgtgctg cgtaggctgc ggaacggtcc acttttgatg gatctttacc
    28501 agagaatgca ccgccaccgt gacgcgccat gccgccgtag gtatcaacga taattttacg
    28561 accagtcaga ccgcagtcac ccattgggcc accgataacg aaacgaccgg tcgggttgat
    28621 gaagaatttg gtggcagaag tcagccattc agcgggcaga attggcttga tgatctcttc
    28681 cattaccgct tcttgcagcg atttctggtc gatctcttca gagtgctgag tggaaagcac
    28741 gacagcatcg ataccaacga ttttgccgtc gtcatactga aaagtcacct ggcttttcgc
    28801 gtccgggcgc agccacggca gagtgccgtt tttacgcact tcagcctgac gctgtaccag
    28861 acggtgtgca taggtgatag gtgctggcat cagcacgtcg gtttcattag ttgcgtagcc
    28921 aaacatcaga ccctggtcac ccgcgccctg ttccagcgga tcggcacggt caacgccctg
    28981 gttgatgtca ggagactgtt tgccgatagc gctcagaacc gcacaggagt tagcgtcaaa
    29041 gcccatgtcg gaatgcacat agccaatttc gcgaacggtg ttacgggtga tctcttcgat
    29101 gtctacccag gcgctggtgg tgatttcgcc gccaactaaa accatgccgg tttttacgta
    29161 ggtttcgcaa gcaacgcgtg ctttcggatc ctgttcgagg atcgcgtcta aaacggcatc
    29221 agaaatttgg tcagcaattt tgtcaggatg cccttcagag acggactcgg acgtaaaaag
    29281 gtgttttgcc atatttaata tcacctaaag agaatttggt tagctcaaac tgttgtgtgg
    29341 attttctgtg gtagcggatc ctaccacgac tctgcaggtt aaaaacactg gcagtctgag
    29401 tgttaatcgg tatggatgga ttaacatctg gatggctatt ttaggtcaat tcttcaccct
    29461 atttccactt ttttttgaat cgtgtctcat tctgttaaaa acgtggctgg aaatttttcc
    29521 tgacaatgcc ggcattctgc gtatttatct tttgcaattt tctgccattg tggggtataa
    29581 aacgcggcgc gcggcttaaa taaaaagcac acgacgtttc tttcgtgttg ccacttccag
    29641 ccgggttgaa atcagagttt tggcttgtgg gttcgtctta acaggcggcc gtggaggtga
    29701 tacgaaataa tgaaccgttg tctgctgctt aacctgtctc accgttctgg tgaagattcg
    29761 ttccccgcac tctgcatctc tgctttgcat acctgccgat gttataccca tctcggcgct
    29821 tctcaggatt caagagctgg ttacagttac tgaggactga acaagggcgc tcttgtaaaa
    29881 acaagagttt tctcgtggtt tcgccgaact ttcacactta cgttcggtta tgtgcttaat
    29941 aatgttatga aaaagaaacc ggttgcgcag ttggagcgtc agcattcact gctggaaaat
    30001 ccatgtgctt atgggttgtt atcgcagttc caggctgcga tagtcgttaa ctgttttaca
    30061 cttaataaaa taatttgagg ttcgctatgt ctgacgacat gtctatgggt ttgccttcgt
    30121 cagcgggcga acacggtgta ctacgctcca tgcaggaggt tgcaatgagc tcccaggaag
    30181 ccagcaagat gctgcgtact tacaatattg cctggtgggg caataactac tatgacgtta
    30241 acgagctggg ccacattagc gtgtgcccgg acccggacgt cccggaagct cgcgtcgatc
    30301 tcgcgcagtt agtgaaaact cgtgaagcac agggccagcg tctgcctgca ctgttctgtt
    30361 tcccacagat cctgcagcac cgtttgcgtt ccattaacgc cgcgttcaaa cgtgcgaggg
    30421 aatcctacgg ctataacggc gattacttcc ttgtttatcc gatcaaagtt aaccagcacc
    30481 gccgcgtgat tgagtccctg attcattcgg gcgaaccgct gggtctggaa gccggttcca
    30541 aagccgagtt gatggcagta ctggcacatg ctggcatgac ccgtagcgtc atcgtctgca
    30601 acggttataa agaccgcgaa tatatccgcc tggcattaat tggcgagaag atggggcaca
    30661 aggtctatct ggtcattgag aagatgtcag aaatcgccat tgtgctggat gaagcagaac
    30721 gtctgaatgt cgttcctcgt ctgggcgtgc gtgcacgtct ggcttcgcag ggttcgggta
    30781 aatggcagtc ctccggcggg gaaaaatcga agttcggcct ggctgcgact caggtactgc
    30841 aactggttga aaccctgcgt gaagccgggc gtctcgacag cctgcaacta ctgcacttcc
    30901 acctcggttc gcagatggcg aatattcgcg atatcgcgac aggcgttcgt gaatccgcgc
    30961 gtttctatgt ggaactgcac aagctgggcg tcaatattca gtgcttcgac gtcggcggcg
    31021 gtctgggcgt ggattatgaa ggtactcgtt cgcagtccga ctgttcggtg aactacggcc
    31081 tcaatgaata cgccaacaac attatctggg cgattggcga tgcgtgtgaa gaaaacggtc
    31141 tgccgcatcc gacggtaatc accgaatcgg gtcgtgcggt gactgcgcat cacaccgtgc
    31201 tggtgtctaa tatcatcggc gtggaacgta acgaatacac ggtgccgacc gcgcctgcag
    31261 aagatgcgcc gcgcgcgctg caaagcatgt gggaaacctg gcaggagatg cacgaaccgg
    31321 gaactcgccg ttctctgcgt gaatggttac acgacagtca gatggatctg cacgacattc
    31381 atatcggcta ctcttccggc atctttagcc tgcaagaacg tgcatgggct gagcagcttt
    31441 atttgagcat gtgccatgaa gtgcaaaagc agctggatcc gcaaaaccgt gctcatcgtc
    31501 cgattatcga cgagctgcag gaacgtatgg cggacaaaat gtacgtcaac ttctcgctgt
    31561 tccagtcgat gccggacgca tgggggatcg accagttgtt cccggttctg ccgctggaag
    31621 ggctggatca agtgccggaa cgtcgcgctg tgctgctgga tattacctgt gactctgacg
    31681 gtgctatcga ccactatatt gatggtgacg gtattgccac gacaatgcca atgccggagt
    31741 acgatccaga gaatccgccg atgctcggtt tctttatggt cggcgcatat caggagatcc
    31801 tcggcaacat gcacaacctg ttcggtgata ccgaagcggt tgacgtgttc gtcttccctg
    31861 acggtagcgt agaagtagaa ctgtctgacg aaggcgatac cgtggcggac atgctgcaat
    31921 atgtacagct cgatccgaaa acgctgttaa cccagttccg cgatcaagtg aagaaaaccg
    31981 atcttgatgc tgaactgcaa caacagttcc ttgaagagtt cgaggcaggt ttgtacggtt
    32041 atacttatct tgaagatgag taagtcctgt gttacttgaa tccgcttaat ttagcggtga
    32101 taatccgcca caatttattg tgacaaatcc aacccttcct cgtcgggcct aacgacgcgg
    32161 aagggttttt ttatatcgac tttgtaatag gagtccatcc atgagcacct taggtcatca
    32221 atacgataac tcactggttt ccaatgcctt tggtttttta cgcctgccga tgaacttcca
    32281 gccgtatgac agcgatgcag actgggtgat tactggcgtg ccgttcgata tggccacttc
    32341 tggtcgtgcg ggtggtcgcc acggtccggc agcgatccgt caggtttcga cgaatctggc
    32401 ctgggaacac aaccgcttcc cgtggaattt cgacatgcgt gagcgtctga acgtcgtgga
    32461 ctgcggcgat ctggtatatg cctttggcga tgcccgtgag atgagcgaaa agctgcaggc
    32521 gcacgccgag aagctgctgg ctgccggtaa gcgtatgctc tctttcggtg gtgaccactt
    32581 tgttacgctg ccgctgctgc gtgctcatgc gaagcatttc ggcaaaatgg cgctggtaca
    32641 ctttgacgcc cacaccgata cctatgcgaa cggttgtgaa tttgaccacg gcactatgtt
    32701 ctataccgcg ccgaaagaag gtctgatcga cccgaatcat tccgtgcaga ttggtattcg
    32761 taccgagttt gataaagaca acggctttac cgtgctggac gcctgccagg tgaacgatcg
    32821 cagcgtggat gacgttatcg cccaagtgaa acagattgtg ggtgatatgc cggtttacct
    32881 gacttttgat atcgactgcc tggatcctgc ttttgcacca ggcaccggta cgccagtgat
    32941 tggcggcctg acctccgatc gcgctattaa actggtacgc ggcctgaaag atctcaacat
    33001 tgttgggatg gacgtagtgg aagtggctcc ggcatacgat cagtcggaaa tcactgctct
    33061 ggcagcggca acgctggcgc tggaaatgct gtatattcag gcggcgaaaa agggcgagta
    33121 agcaccagat gcgatgcgca cgggtaaaac gtgccattaa tgtcggatgc ggcgtgaacg
    33181 ccttatccga cctacgttcg gcacccgtag gccggataag atgcgccagc atcgcatccg
    33241 gcaatgcgca caaggtaaca aatgtgccat tcatgtcaga tgcggcgtga acgccttatc
    33301 tgacctacgt tcgacaccac caggctttac ttaatcccat ccgcgctcat gcgatcgcga
    33361 atatgctggg cgcgttcggc ggatgcagga tggtcgtcaa acattgagct ttggcgacct
    33421 tcttccagtt ttgccagttt ttcaaagctg gtggcaagac ctgccgggct gatgccgcgt
    33481 tggcgcagaa gatcgtaaga ataatcatcg gcttctgctt cctggcgctg ggagaattgc
    33541 gaattgacta atttctcgcc cagattacca agttgtgatt gagataaact tccgacaatc
    33601 ccgcccgcag aggccgcagc tactcgcacg gcatttgtac caagtgccac ctgcattcct
    33661 tttttcacat ggcctaacgc cacgtgcccc atttcgtgac cgatcaccgc ttcgacttcg
    33721 ttatccgtca tcatatccat cagcccgcta tagacgcgga tacagccgtt agccattgca
    33781 aaggcgttca catccttcgc catatacact ttgtaattta ccggctgacc gttgatattg
    33841 ttgcctagcg cattggcaat agttgtcaga cgtttagcgt attcgctatt ggctggcgca
    33901 atcgtcgcct tgctgtccat ctcctgacat gcctgatcgc tcagggtttt cacctgcgca
    33961 tcactcaaac tgtaagcctg aaaagcttcc gctcctgatg agagcagtcc gttggagtcc
    34021 atattctggc aaccagtcag taccgttgcc acgctcattg ctaccaataa ggcgcgaatt
    34081 ttcatgtttt ctcttccgca caaggtcagg attattctaa aaatgcgccg tttgcaggtg
    34141 aatcgacgct cagtctcagt ataaggaaaa gcgcagcgga cgggcgagta gattgcgcaa
    34201 catgcgagca tgatccagag atttctgaag cggcaaaagg atgttccatg tacatgacgc
    34261 gcggcttgcg gtaaattgtt ggcaaatttt ccggcgtagc ccaaaacgcg ctgtcgtcaa
    34321 gtcgttaagg gcgtgccctt catcatccga tctggagtca aaatgtcctc acgtaaagag
    34381 cttgccaatg ctattcgtgc gctgagcatg gacgcagtac agaaagccaa atccggtcac
    34441 ccgggtgccc ctatgggtat ggctgacatt gccgaagtcc tgtggcgtga tttcctgaaa
    34501 cacaacccgc agaatccgtc ctgggctgac cgtgaccgct tcgtgctgtc caacggccac
    34561 ggctccatgc tgatctacag cctgctgcac ctcaccggtt acgatctgcc gatggaagaa
    34621 ctgaaaaact tccgtcagct gcactctaaa actccgggtc acccggaagt gggttacacc
    34681 gctggtgtgg aaaccaccac cggtccgctg ggtcagggta ttgccaacgc agtcggtatg
    34741 gcgattgcag aaaaaacgct ggcggcgcag tttaaccgtc cgggccacga cattgtcgac
    34801 cactacacct acgccttcat gggcgacggc tgcatgatgg aaggcatctc ccacgaagtt
    34861 tgctctctgg cgggtacgct gaagctgggt aaactgattg cattctacga tgacaacggt
    34921 atttctatcg atggtcacgt tgaaggctgg ttcaccgacg acaccgcaat gcgtttcgaa
    34981 gcttacggct ggcacgttat tcgcgacatc gacggtcatg acgcggcatc tatcaaacgc
    35041 gcagtagaag aagcgcgcgc agtgactgac aaaccttccc tgctgatgtg caaaaccatc
    35101 atcggtttcg gttccccgaa caaagccggt acccacgact cccacggtgc gccgctgggc
    35161 gacgctgaaa ttgccctgac ccgcgaacaa ctgggctgga aatatgcgcc gttcgaaatc
    35221 ccgtctgaaa tctatgctca gtgggatgcg aaagaagcag gccaggcgaa agaatccgca
    35281 tggaacgaga aattcgctgc ttacgcgaaa gcttatccgc aggaagccgc tgaatttacc
    35341 cgccgtatga aaggcgaaat gccgtctgac ttcgacgcta aagcgaaaga gttcatcgct
    35401 aaactgcagg ctaatccggc gaaaatcgcc agccgtaaag cgtctcagaa tgctatcgaa
    35461 gcgttcggtc cgctgttgcc ggaattcctc ggcggttctg ctgacctggc gccgtctaac
    35521 ctgaccctgt ggtctggttc taaagcaatc aacgaagatg ctgcgggtaa ctacatccac
    35581 tacggtgttc gcgagttcgg tatgaccgcg attgctaacg gtatctccct gcacggtggc
    35641 ttcctgccgt acacctccac cttcctgatg ttcgtggaat acgcacgtaa cgccgtacgt
    35701 atggctgcgc tgatgaaaca gcgtcaggtg atggtttaca cccacgactc catcggtctg
    35761 ggcgaagacg gcccgactca ccagccggtt gagcaggtcg cttctctgcg cgtaaccccg
    35821 aacatgtcta catggcgtcc gtgtgaccag gttgaatccg cggtcgcgtg gaaatacggt
    35881 gttgagcgtc aggacggccc gaccgcactg atcctctccc gtcagaacct ggcgcagcag
    35941 gaacgaactg aagagcaact ggcaaacatc gcgcgcggtg gttatgtgct gaaagactgc
    36001 gccggtcagc cggaactgat tttcatcgct accggttcag aagttgaact ggctgttgct
    36061 gcctacgaaa aactgactgc cgaaggcgtg aaagcgcgcg tggtgtccat gccgtctacc
    36121 gacgcatttg acaagcagga tgctgcttac cgtgaatccg tactgccgaa agcggttact
    36181 gcacgcgttg ctgtagaagc gggtattgct gactactggt acaagtatgt tggcctgaac
    36241 ggtgctatcg tcggtatgac caccttcggt gaatctgctc cggcagagct gctgtttgaa
    36301 gagttcggct tcactgttga taacgttgtt gcgaaagcaa aagaactgct gtaattagca
    36361 tttcgggtaa aaaggtcgct tcggcgacct tttttattac cttgatatgt ccgtttgcgg
    36421 acaagcaata gataaggcgt gttgtagatc acaaatat
//
LOCUS       DAPHKZ010000039        35568 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.039, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000039 DAPHKZ010000000
VERSION     DAPHKZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35568
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.039"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..442)
                     /locus_tag="RH288_001998"
     CDS             complement(<1..442)
                     /locus_tag="RH288_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HDV4031048.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDLALPGPLPFILSRTYSSYRTKTPAPVGSLGPGWKMPADI
                     RLQLRDNTLILSDNGGRSLYFEHLFPGEDGYSRSESLWLVRGGVL"
     gene            complement(645..1046)
                     /gene="nikR"
                     /locus_tag="RH288_001999"
     CDS             complement(645..1046)
                     /gene="nikR"
                     /locus_tag="RH288_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HDV4031049.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEA
                     TQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(1052..1858)
                     /gene="nikE"
                     /locus_tag="RH288_002000"
     CDS             complement(1052..1858)
                     /gene="nikE"
                     /locus_tag="RH288_002000"
                     /EC_number="7.2.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikE"
                     /protein_id="HDV4031050.1"
                     /translation="MTLLNISGLSHHYAHGGFNGKHQHQAVLNNVSLTLKSGETVALL
                     GRSGCGKSTLARLLVGLESPAQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAV
                     NPRKTVREILREPMRHLLSLKKSEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRV
                     CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERF
                     CQRVMVMDNGQIVETQVVGEKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV"
     gene            complement(1855..2619)
                     /gene="nikD"
                     /locus_tag="RH288_002001"
     CDS             complement(1855..2619)
                     /gene="nikD"
                     /locus_tag="RH288_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikD"
                     /protein_id="HDV4031051.1"
                     /translation="MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSL
                     TCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHA
                     RETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
                     FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSDGK
                     IVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS"
     gene            complement(2619..3452)
                     /gene="nikC"
                     /locus_tag="RH288_002002"
     CDS             complement(2619..3452)
                     /gene="nikC"
                     /locus_tag="RH288_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikC"
                     /protein_id="HDV4031052.1"
                     /translation="MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSR
                     LLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLVIGGSAGLIGGR
                     VDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
                     RQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVT
                     APTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHA
                     H"
     gene            complement(3449..4393)
                     /gene="nikB"
                     /locus_tag="RH288_002003"
     CDS             complement(3449..4393)
                     /gene="nikB"
                     /locus_tag="RH288_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikB"
                     /protein_id="HDV4031053.1"
                     /translation="MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNL
                     PPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFASQRPVLDDMLNFLPATL
                     ELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
                     YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLND
                     KQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPV
                     IQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA"
     gene            complement(4393..5967)
                     /gene="nikA"
                     /locus_tag="RH288_002004"
     CDS             complement(4393..5967)
                     /gene="nikA"
                     /locus_tag="RH288_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HDV4031054.1"
                     /translation="MLSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLY
                     TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFD
                     AEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRP
                     FRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITF
                     NVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALN
                     TAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPSQYDP
                     QKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGAD
                     VSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADK
                     PLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYA
                     PIATEIPFEQIKPVKP"
     gene            complement(6078..6665)
                     /gene="acpT"
                     /locus_tag="RH288_002005"
     CDS             complement(6078..6665)
                     /gene="acpT"
                     /locus_tag="RH288_002005"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HDV4031055.1"
                     /translation="MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHT
                     LSPLPEIIYGEQGKPAFAPEMPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRANWR
                     WLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYHSS
                     LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN"
     gene            complement(6720..7769)
                     /locus_tag="RH288_002006"
     CDS             complement(6720..7769)
                     /locus_tag="RH288_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDV4031056.1"
                     /translation="METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELT
                     RKLFKLQEMLPFLNLHMSPERMLQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVF
                     MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELM
                     GVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGVYECILVGALFLVVHMVIG
                     NILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            7901..9118
                     /locus_tag="RH288_002007"
     CDS             7901..9118
                     /locus_tag="RH288_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417930.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4031057.1"
                     /translation="MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYV
                     HDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADSLGPKKIVVFGLCGCFLSGLGYLT
                     AGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTY
                     GAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLG
                     RVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGIN
                     RIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVP
                     QQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWRLKK
                     RPPEHVPEAASSS"
     gene            complement(9122..9679)
                     /gene="dcrB"
                     /locus_tag="RH288_002008"
     CDS             complement(9122..9679)
                     /gene="dcrB"
                     /locus_tag="RH288_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage sensitivity protein DcrB"
                     /protein_id="HDV4031058.1"
                     /translation="MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVN
                     LLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATGQKAVIVIMGDDPKEDLAVLAKR
                     LEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
                     ITLPADDQQKAQTTAENIINTLVIQ"
     gene            complement(9752..10417)
                     /locus_tag="RH288_002009"
     CDS             complement(9752..10417)
                     /locus_tag="RH288_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HDV4031059.1"
                     /translation="MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSILGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALA
                     HFNLFVARIATASFMAYALGQILDVHVFNRLRQSRRWWLAPTASTLFGNVSDTLAFFF
                     IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINAL
                     QAS"
     gene            10638..10883
                     /gene="tusA"
                     /locus_tag="RH288_002010"
     CDS             10638..10883
                     /gene="tusA"
                     /locus_tag="RH288_002010"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HDV4031060.1"
                     /translation="MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIAD
                     DPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG"
     gene            complement(10985..13183)
                     /gene="zntA"
                     /locus_tag="RH288_002011"
     CDS             complement(10985..13183)
                     /gene="zntA"
                     /locus_tag="RH288_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HDV4031061.1"
                     /translation="MSTPDNHGKKAPQFAAFKPLTTVQNANDCCCDGACSSTPTLSEN
                     VSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVES
                     ALQKAGYSLRDEQAAEEPQASRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATT
                     LVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARQGVSALMALKPETATRLRKGEREEVAINSLRPGDVIEVAAGGRLPADGKLL
                     SPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIE
                     EAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTA
                     IHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEA
                     QVNGERVLICAAGKHPADAFTGLINELESAGQTVVLVVRNDDVLGVIALQDTLRADAA
                     TAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTELNQHAPLA
                     MVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANI
                     RQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRR"
     gene            complement(13257..13883)
                     /locus_tag="RH288_002012"
     CDS             complement(13257..13883)
                     /locus_tag="RH288_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HDV4031062.1"
                     /translation="MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
                     AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            14024..14383
                     /locus_tag="RH288_002013"
     CDS             14024..14383
                     /locus_tag="RH288_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HDV4031063.1"
                     /translation="MSKPPLFFIVIIGLIVVAASFRFMQQRREKADNDMAPLQQKLVV
                     VSNKREKPINDRRSRQQEVTPAGTSIRYEASFKPQSGGMEQTFRLDAQQYHALTVGDK
                     GTLSYKGTRFVSFVGEQ"
     gene            complement(14386..14655)
                     /locus_tag="RH288_002014"
     CDS             complement(14386..14655)
                     /locus_tag="RH288_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HDV4031064.1"
                     /translation="MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMH
                     GMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLAWQKKFKVKK"
     gene            complement(14645..15241)
                     /gene="rsmD"
                     /locus_tag="RH288_002015"
     CDS             complement(14645..15241)
                     /gene="rsmD"
                     /locus_tag="RH288_002015"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HDV4031065.1"
                     /translation="MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGN
                     ARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEV
                     ENGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD"
     gene            15391..16887
                     /gene="ftsY"
                     /locus_tag="RH288_002016"
     CDS             15391..16887
                     /gene="ftsY"
                     /locus_tag="RH288_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDV4031066.1"
                     /translation="MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEP
                     VKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETP
                     EPVAIEREELPLPEDVNAEEVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELEAQAL
                     AAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISL
                     FRGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEM
                     GEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFR
                     AAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKS
                     HLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLD
                     GTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            16890..17558
                     /gene="ftsE"
                     /locus_tag="RH288_002017"
     CDS             16890..17558
                     /gene="ftsE"
                     /locus_tag="RH288_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDV4031067.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGG
                     VGHE"
     gene            17551..18609
                     /gene="ftsX"
                     /locus_tag="RH288_002018"
     CDS             17551..18609
                     /gene="ftsX"
                     /locus_tag="RH288_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HDV4031068.1"
                     /translation="MNKRDAINHIRQFGGRLDRFRKSVGGSGDGGRNAPKRAKSSPKP
                     VNRKTNVFNEQVRYAFHGALQDLKSKPFATFLTVMVIAISLTLPSVCYMVYKNVNQAA
                     TQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
                     ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALT
                     GLVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGG
                     ALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSFDECLLLLLVCSMIG
                     WVAAWLATVQHLRHFTPE"
     gene            18854..19708
                     /gene="rpoH"
                     /locus_tag="RH288_002019"
     CDS             18854..19708
                     /gene="rpoH"
                     /locus_tag="RH288_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HDV4031069.1"
                     /translation="MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYH
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            19979..21082
                     /gene="livJ"
                     /locus_tag="RH288_002020"
     CDS             19979..21082
                     /gene="livJ"
                     /locus_tag="RH288_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
                     /protein_id="HDV4031070.1"
                     /translation="MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQ
                     EFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMITPAATAPELTARSYQLILRTTGLDSDQGPTAAKYILEKVK
                     PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENID
                     FVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYD
                     QVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDT
                     VMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK"
     gene            complement(21282..21665)
                     /gene="panM"
                     /locus_tag="RH288_002021"
     CDS             complement(21282..21665)
                     /gene="panM"
                     /locus_tag="RH288_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HDV4031071.1"
                     /translation="MKLTIIRLENFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARF
                     NERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPGVSCWWMADAGV
                     EDRGVMTAFMQALGFTAQQGGWEKR"
     gene            22089..23198
                     /gene="livK"
                     /locus_tag="RH288_002022"
     CDS             22089..23198
                     /gene="livK"
                     /locus_tag="RH288_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HDV4031072.1"
                     /translation="MKRNAKTIIAGMIALAISHTAMADDIKVAVVGAMSGPIAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENID
                     FVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYD
                     QDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA
                     NTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK"
     gene            23246..24172
                     /gene="livH"
                     /locus_tag="RH288_002023"
     CDS             23246..24172
                     /gene="livH"
                     /locus_tag="RH288_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HDV4031073.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMMGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            24169..25446
                     /gene="livM"
                     /locus_tag="RH288_002024"
     CDS             24169..25446
                     /gene="livM"
                     /locus_tag="RH288_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HDV4031074.1"
                     /translation="MKPMHIAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDSASDVR
                     WQWVFIGTAVVFFFQLLRPAFQKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVA
                     WPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTFFGLEFSRTAREGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAILLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKNGAAKGEQA"
     gene            25443..26210
                     /gene="livG"
                     /locus_tag="RH288_002025"
     CDS             25443..26210
                     /gene="livG"
                     /locus_tag="RH288_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HDV4031075.1"
                     /translation="MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGTPLANGTPEQIRNNPDVIRAYLGEA"
     gene            26212..26925
                     /gene="livF"
                     /locus_tag="RH288_002026"
     CDS             26212..26925
                     /gene="livF"
                     /locus_tag="RH288_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HDV4031076.1"
                     /translation="MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDQFQERIKWVYELFPRLHERRVQRAGTMSGGEQQMLAIGRALMSNPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDVLLANEAVRSAYLGG"
     gene            27322..28638
                     /gene="ugpB"
                     /locus_tag="RH288_002027"
     CDS             27322..28638
                     /gene="ugpB"
                     /locus_tag="RH288_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HDV4031077.1"
                     /translation="MKPLHYTASALALGLALMGNAQAVTTIPFWHSMEGELGKEVDSL
                     AQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGN
                     MPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS"
     gene            28736..29623
                     /gene="ugpA"
                     /locus_tag="RH288_002028"
     CDS             28736..29623
                     /gene="ugpA"
                     /locus_tag="RH288_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HDV4031078.1"
                     /translation="MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLDNFVTLFHDSYYLDSFWTTIKFSTFVTVSGLLVSLFFAALVEYIVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFL
                     VIVLTVVQFRYVESKVRYQ"
     gene            29620..30465
                     /gene="ugpE"
                     /locus_tag="RH288_002029"
     CDS             29620..30465
                     /gene="ugpE"
                     /locus_tag="RH288_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HDV4031079.1"
                     /translation="MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAA
                     PMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLQMLDSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGL
                     VDSEK"
     gene            30467..31537
                     /gene="ugpC"
                     /locus_tag="RH288_002030"
     CDS             30467..31537
                     /gene="ugpC"
                     /locus_tag="RH288_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol 3-phosphate ABC transporter ATP
                     binding protein UgpC"
                     /protein_id="HDV4031080.1"
                     /translation="MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTEGDIWINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDE
                     PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGT
                     PVEVYEKPASLFVASFIGSPAMNLLTGRVNNEGTHFELDGGIELPLNGGYRQYAGRKM
                     TLGIRPEHIALSSQAEGGVPMVMDTLEILGADNLAHGRWGEQKLVVRLAHQERPTAGS
                     TLWLHLAENQLHLFDGETGQRV"
     gene            31534..32277
                     /gene="ugpQ"
                     /locus_tag="RH288_002031"
     CDS             31534..32277
                     /gene="ugpQ"
                     /locus_tag="RH288_002031"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDV4031081.1"
                     /translation="MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAE
                     RCREHGMMANIEIKPTTGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQQAV
                     PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKP
                     QRAAELLRWGVDCICTDAIDVIGPNFTAQ"
     gene            complement(32264..32704)
                     /locus_tag="RH288_002032"
     CDS             complement(32264..32704)
                     /locus_tag="RH288_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HDV4031082.1"
                     /translation="MKRLLILTALLPFVGFAQPINTLNNPNQPGYQIPSQQRMQTQMQ
                     TQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRVLQSQPGERNPARQQMLPNTNGG
                     MLNSNRNPDSSLNQQHMLPERRNGDMLNQPSTPQPDIPLKTIGP"
     gene            32824..34566
                     /gene="ggt"
                     /locus_tag="RH288_002033"
     CDS             32824..34566
                     /gene="ggt"
                     /locus_tag="RH288_002033"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDV4031083.1"
                     /translation="MIKPTFLRRVAIAALLSGSCFSAAAAPPAPPVSYGVEEDVFHPV
                     RAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIR
                     SKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDK
                     YGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKK
                     GDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERT
                     PISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAY
                     ADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQTT
                     HYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGD
                     ANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGLNVAEA
                     TNAPRFHHQWLSDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYG
                     ASDPRSVDDLTAGY"
     gene            complement(34604..34888)
                     /locus_tag="RH288_002034"
     CDS             complement(34604..34888)
                     /locus_tag="RH288_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhB family protein"
                     /protein_id="HDV4031084.1"
                     /translation="MITYHDAFAKANHYLDDADLPVVITLHGRFSQGWYFCFEAREFL
                     ETGDEAARLAGNAPFIIDKDSGEIHSLGTAKPLEEYLQDYEIKKATFGLP"
     gene            complement(35088..35243)
                     /locus_tag="RH288_002035"
     CDS             complement(35088..35243)
                     /locus_tag="RH288_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031085.1"
                     /translation="MEKLTTELHSLSEMDRRHVVSILAEIANGYDDFNDMLIYLEFYP
                     NHKILIS"
     gene            complement(35338..>35568)
                     /locus_tag="RH288_002036"
     CDS             complement(35338..>35568)
                     /locus_tag="RH288_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001759491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031086.1"
                     /translation="SVKNLFAVNEFYRNNDDFINPDLQERLVIGDYSISIFTYDIKSN
                     FFEIRDNIGTENIFSSFSDFSSFLNEIMDSCS"
BASE COUNT         8281 a         9185 c         9912 g         8190 t
ORIGIN      
        1 tcaggacgcc gccgcgcacc agccacagtg actcgctgcg gctgtaaccg tcctcaccgg
       61 gaaacaggtg ctcaaaatac aggcttctgc cgccgttatc actgagtatc agtgtgttat
      121 cgcgcagctg taagcggata tccgcaggca ttttccagcc ggggccgagg ctccccaccg
      181 gcgcgggcgt ttttgtccgg taactgctgt aggtgcggga gaggatgaac ggcagcgggc
      241 cgggcagggc aaggtcggtt tcaccgggaa ggacctttgc accgagcagg ggattgaccg
      301 gatggccgga cgtcactccg ccggggcaca ccgaacaggc cacgccggtg ggggcaccaa
      361 tacgtacccc ggctgaaccc tgaacaatgc taccgccata ctgcgtcatg tcaccctgac
      421 gcgccgccgg ttttccgctc atcgtaaaat ccttttctat tattttaatg acagtatctt
      481 catacgaaaa agcgaagaaa aacttgtggt cacaatgaat tgaagatttt taggaatata
      541 tttagaacgt tacaaaagag aaggttcgga tagggtattt agagaggaat caggtgtgct
      601 agtggccctt tgttgatcgt tcaccaaagg acccaataat agactcaatc ttccttcggc
      661 aagcactgca aatgcccgtg ccgcacgccg cgctgggcga taacgtcatc ggcaaaatgc
      721 tgcacgtcac ccatgtcacc tttcaacacg gcgatttcca gacagtcgtc gtggttgatg
      781 tgcacatgca gcgtggcgac ggagaggtcg tggtgatgat gctgggtgga gacaatgcgg
      841 ctggctaagt cgcgtttttc gtgttcatac acatacgaca gcaccgcgaa accttgcgtg
      901 ccgtgctgct gggtggcctc ttgcgccagg gcgctacgca gaatgtcgcg gatagcttcg
      961 gaacggttgt tataaccacg acgctggctc aggctgtcca gcgtctccag taaatcgtca
     1021 tcaagcgtga tggtgactcg ttgcatttgc gttaaacctt ttctgtggtg cgacggcgca
     1081 cggggaatgc gggtaatacc gcgttttgta gcacacgtcc ggcgtcagag gaaaaggtta
     1141 atttctctcc caccacctgg gtttcgacga tttgtccgtt gtccataacc attacccgct
     1201 ggcaaaagcg ttctaccagg cgtaagtcgt gggtgatgaa caggcaggcg gtgccaaact
     1261 gttgttgtag ctttttcagc aggcgaatga cacccgcctg taacacgaga tcaaggttag
     1321 aaacggcttc atccagaatc agtagtttcg gttcgaccgc cagcgcgcga gccaggcaga
     1381 cgcgctggag ctggccgccg cttaactgcg gtgggcgttt gtcgagaacg ctgtcatcga
     1441 gatcgaccgc cttcagcatt tcgctggcgc gcgccagttg ttcggatttt ttcagtgata
     1501 gcaggtggcg catcggttca cgcaggatct cgcgcacggt tttgcgcgga ttcacggcgc
     1561 tgatggagtc ctgaaatacc atctgaatat cgcggcggaa cgctttacgc tgggcgcgat
     1621 tgagtttcgc cagcggttcg ccacgccagc taatattccc ctgcgcgggc gattctaaac
     1681 ccaccagcaa ccgcgcgagg gtacttttcc cgcagccgct gcgccccagc agggcgacgg
     1741 tttcgccgct tttcagggtc agggaaacgt tattcagcac cgcctgatgt tgatgttttc
     1801 cgttaaatcc accgtgcgca tagtgatggg aaaggccgga gatgttaagt aaagtcatga
     1861 tgccagctcc ataccgtaga gggcgagatg agcggaaacc aggctgcgcg tcactgtatg
     1921 tttgggggcg ttaaacagcg tttctacatc gccctgttcg acaatcttac cgtcagacat
     1981 caccgccacg tcatccgcca gacgcgccac aacgcccata tcatgggtca ccagcagcat
     2041 tcccggcgct tgtttttgca taatgctttc cagcagatcg aggatgcgcg cctgtgctac
     2101 cacgtcgagg tcggtggtcg gttcatcggc gatgataaac ggtgattcac acagcaccgc
     2161 catcgcaatc atcatgcgct gcaacatgcc gccgctcatc tcgaacgggt acagcttcag
     2221 cacgcgcgcg gcgttttcca gccccaccgc ttctatggca gcggtaagcg tagcgtcatc
     2281 ggcgggtttc cctaacgcca ggcaggtttc ccgcgcgtgg gtgtgcatgg tgtgcagtgg
     2341 attaaaggcg ctgcgcgggt tctgcatgat ggtggcaatt ttgatgccgc gcagggcgca
     2401 aggcgaaacc ggtttgccat cggctaaaat ttcccccgcc gtctggcgaa cgccagcggg
     2461 caaaatgccc agcgtcgcgg cgcaggttaa tgatttcccg ctgccgctac cgccgactaa
     2521 cgccagcacg cgcccgcgtt gcagggttaa cgatacaccg tgtaccagcg gctgcgcggc
     2581 ctgtagcgcg atattacgta gttcaatctg ttgcggcatt agtgtgcgtg ctccgtcacc
     2641 agatgagggt ccagatgatc gcgcagtgcg tcacccacca ggttaaaggc catcacgctg
     2701 ataaacagcg ccagccccgg ccagaacatt tgcagcggct gggtccagat atactggcgc
     2761 gcgtcgttaa tcatcacgcc ccattcggcg gtcggcgcgg tcacaccgag gccaaggaaa
     2821 gacatccccg cgacgtgcag catcatatgg ccgatatcca gcgttgccag caccagcagc
     2881 gaagggatca ccgcgcctgc cagatgatcg acaaacaccc gcacatggcc cgcaccggaa
     2941 agccgtgacg ccagcacaaa ctcgcgttgg cgtagtgaaa tcaccaggct gcgcaccatg
     3001 cgtgcatacc acgcccagtg cgacagggcg atggcgataa ttacgttggt cagcccggtg
     3061 ccgagcacgc caaccataaa gaacgacaga atcgaggtcg ggaaggtcat aaacatatcg
     3121 gcgacgcgca tggtggcctg atcaacgcgc ccgccaatca acccggcgct gccgccaata
     3181 accagcccta atgtcagcac cagcagcagg caggccatta ccgaaccgag cgacacgcgg
     3241 gtcgctgcca tcagccgcga gaaaatatcg cgacctaagt gatcggtgcc cagccagtgc
     3301 tgcgcatccg gcgaaagcag gcgcgacggc aaatcaatcg cctgggggtc atacggcagc
     3361 caccactggc tggtgagcgc aatcagcgcc agcagggcga taatgatcag cgccaggcgt
     3421 accgaccagc gggaagagag gaaaaagttc acgcgtgcgc tccttcatga cgacgaatgc
     3481 gcgggtccag cgcggcgttg agcaaatcga caatcaaatt acagaccaca aaaaccacca
     3541 ccatcatcag cgtaaagcac tggatcaccg gatagtcacg gttaaaaatc gccgacaccg
     3601 catagcgccc gacgcccggc caggcaaaga tgttttcgat aatcatcgtc ccgccaatca
     3661 gttcgccgat atgcatcccc acggcggtga tcatcggcag cgaggcattg cgcaggatgt
     3721 ggcgacgttc ggtctgtttg tcgttcaggc cgcgcagacg cgcccaggtg acgtgacgct
     3781 gaccggcgac gtccagcata ctggcgcgca gtaaacgcgc gttaatcgcc agcgacataa
     3841 aggcaatgga aaccgcaggc aaaatgatgt gctgccagcc gccgtaaccc atcgcgggta
     3901 gccattgcag atacaccgaa aacgccatca ccagtaaaaa cgccagccag aagttaggca
     3961 tcgacacgcc aagaaacgcg atgaaacgta cggcgaaatc cggcagacgg tcgcgatggc
     4021 gcgccgccca gataccgagc ggtacggaag tgagcagaat taataccagc gccgcacctg
     4081 caagttccag cgtggcgggc aggaagttca gcatatcgtc cagtaccggg cgttggctgg
     4141 cgaatgagat accaaagtca agatgcagcg ccttccacaa ccaggtgccg tactggacgt
     4201 acagcggctg atccagtccc agcatggtgc gggtagaggc cagcatctcc ggcgtcggcg
     4261 gcaggttaga cagacgcaaa taatcgagcg ccgggtcgcc ggtaccgagg cgcagcatca
     4321 gaaaaatgat caccgaggcg gcgagcacca tcgggatcag cagcagaaag cggcgtaata
     4381 cgtaacgcaa cattaaggtt tcaccggttt aatctgttcg aacggaattt cggtggcgat
     4441 cggcgcgtag gggatgttac ccagctccgg ttttgatacc accatcattg agatgtaact
     4501 gataggcaga taaaccgcct cgtcatgcag acgggtcaga atgtcgcgat acagcgcctg
     4561 acgttgcgtt tcgtcatggg tcgccagcac ttcgccgatc tctttatcaa tcagcggttt
     4621 gtcggctaat ccttgctgtg cctggaagtc agcgtgtgac ggtacgcgca ttgaactgag
     4681 gaaggcgtgt ggatcatatg gcgcgcccca ggtgcggtgg aaaatcatgc caaaacgacc
     4741 gtcgcgctga cgagcataga tactgctctc ttcttcgcca atcagcgaga catctgcgcc
     4801 aatctggcgc atatcagcct gaatgatttc cgccatcgat ttgcttaacg catcggtgcc
     4861 gatgaacgaa agttcaatgc gcagcggctg accatttttc tcgcggatgt ctttgcccgc
     4921 aggcagcgtc caaccggctt tttccagcaa cgctttcgct ttttgcggat cgtactggct
     4981 cggtttcagg ccgaggttgg cgtagggcac agaaggggca aacagggtgt cggcgacctg
     5041 ctgggtgcca tacaacgcgt tatcaatcag cgattttttg tttaccgcgt aattaagagc
     5101 ttcacgtact gccagctcgt tggtgggggc tttggcggta ttgagcgcca gcatcacggt
     5161 ttcgatcggc tgtgacagtt gggtgtggta agccggattc tggctaaagc gggcgaaggt
     5221 atcgagcggt aataaccctt cgtttccgta cagcaggtcg atatcgccag tttcaaacgc
     5281 caccgcgcgg gtagtcgggt ccgggatgac gttaaaggtg atctttttaa tcgctggctt
     5341 ttcgccccag tagttttcgt tacggacgaa gacatcgtac tgattcagtt tcgattcctg
     5401 caaaatccac ggtccggtgc caatcggcgc tttaattccg ttcatggttt catggttttt
     5461 aaactgcgag ggagcgataa aacggaaagg acggggcagg gccagttctt gcaggaaagg
     5521 atagtaggcg cttttcaggg taatttgcag ctctgtttta ctgagtgctt taacatcaac
     5581 aatctggttt gccagctcca gccaggcgtg acgttgacgg ttatcgagca ctgcgcggaa
     5641 gttttctgcc gccgcctcgg catcgaacgg ttcaccgttg gagaatttca cgtcatcacg
     5701 cagggtgaag gtccaggttt taccatcttc tgaatgagtc cagctttttg ccagccacgg
     5761 gatcaccgaa ccgtctgcct gatatttcac caatggttca taaaccatgc tctgggcgaa
     5821 catctggtta ggcgtgtaaa ggtgcgggtt tagtggcccg acattcaccg gccaggcggt
     5881 ggtgatttca tctggtgcag cggcatggac gataaaagac gcacaagcca gcagcgcaaa
     5941 tagagtgcgg cggagtgtgg agagcatggt aaccccaatg gattaaaata gatggcggaa
     6001 ataagtatga cgattttaag tattcgtcat actgattacc tgttctggat caatagatgg
     6061 gcagtcgggt gggcggatca gttaactgaa tcgatccatt gcacactgtc ggcggtgagc
     6121 gtaaagggag taggggtgca gatcgcaagg cttaaatttt caagctgaca atggctgact
     6181 gacagcgagg agtgataggt gctgtctacg ctgacgattt gccaggcgct gccgccacgc
     6241 tgtttaacga tggcttcttt gcgcgtccag atgcgccaga acatttccag ttgctgatca
     6301 ggatgcacgg cgtccatctc agcgtgttcc ccgaggctga atacggcgtt cgccagccag
     6361 cgccagttgg cgcgcgggcg aatcacttcg atatcgcagc cgacttcgcc ttcatcactc
     6421 aacagcaggg cgatatcgtc accgctatgg cttaagttga accatagcgg catttccggc
     6481 gcaaatgcag gtttgccttg ttcgccatag atgatctccg gtagcgggga aagcgtgtgc
     6541 gaaagcaatg cacgccccgc cagccagcgt tcgcgtcgtg gaccttgcgg tgcttgctcg
     6601 cgtaaacccg gtggcagtgg agctgcgctt aaggtcgaaa ctttccccag aactatccga
     6661 tacatatcag ggccaacgtt taatggaaaa tgaaagtgcg tatcgtatca cttgtcgcct
     6721 catcccggta accgactttt cggtctgccc ggccccagta aaatcgccag tttgctaccg
     6781 cctttggtgg tttccatcca gattttacac acgctggtta atggcaccga aagtagcatc
     6841 cctaccgggc cgagcagcca tccccaaatt aacaatgaaa gaaataccac catggtggac
     6901 atccccaggc gatggcccat catccgtggt tctaaaatat tgccgatgac catatggacc
     6961 actaaaaaca atgcgccgac cagaatacat tcgtaaacac cattaaacag cagcacctga
     7021 atcattggcg gtacggcgga aattaccgcg ccgatattgg gcacgtagtt gagcaaaaac
     7081 gccagtactg cccacatcag cgcaaactgc acccccatca gctccagccc cagccagacg
     7141 atgacacctg tccataaact gagtagcgtc ttcaatgcaa gatagtgcga aacgccttta
     7201 agtgcgcggt gtaatcccgc gatgtgaatc tgtggattat tcagcgcaaa acgcattttg
     7261 taagggacgt ggcgcacttc aaacagcata aaaactacgg tcatcaccag caaaagcacg
     7321 ctcgccattg ccccggaaag cccggtcatt agcgctgtgg tgaaggtaac cactttttcc
     7381 gagtccatcc gctgcagcat tcgctccggc gacatatgca aattaagaaa aggcaacatc
     7441 tcctgcaatt taaaaagttt gcgcgtcagc tccttattaa acttcggcag catagagata
     7501 aattcgttaa acgatgccgc cagtacgccg accagcgcgg ttagtgcgat cagcatcacc
     7561 accactacaa tcgtaatggc aacggggcgt tgtactcccc gacgaataaa ccaggtgacg
     7621 agcgggttga ggacgatggc aaaaaacagc gccagtaaca gctgcacaat gatatctgcc
     7681 gctgcgtgaa tgcccgcgag gatcactacc agcgaggcca gcttgagcag aatgtgcatg
     7741 cccgttttat cgggttgagg ggtttccatt ggggcttcct tgtgactttt tgtattaagt
     7801 gtagcgggag tcacgccagc aatattctga ttcttactgc tgattttcac gtcagcacgt
     7861 ggtaaaaatg aaacactgtt gtaaaaatgt ggtgatcctc atgcccgaac ccgtagccga
     7921 acccgcgcta aacggattgc gcctgaattt gcgcattgtc tctatagtca tgtttaactt
     7981 cgccagctac ctcaccatcg ggttgccgct cgctgtatta ccgggctatg tccatgatgt
     8041 gatgggcttt agcgccttct gggcaggatt ggttatcagc ctgcaatatt tcgccacctt
     8101 gctgagccgc cctcatgccg gacgttacgc cgattcgctg ggacccaaaa agattgtcgt
     8161 cttcggttta tgcggctgct ttttgagcgg tctggggtat ctgacggcag gattaaccgc
     8221 cagtctgcct gtcatcagcc tgttattact ttgcctgggg cgcgtcatcc ttgggattgg
     8281 gcaaagtttt gccggaacgg gatcgaccct atggggcgtt ggcgtggttg gctcgctgca
     8341 tatcgggcgg gtgatttcgt ggaacggcat tgtcacttac ggggcgatgg cgatgggtgc
     8401 gccgttaggc gtcgtgtttt atcactgggg cggcttgcag gcgttagcgt taatcattat
     8461 gggcgtggcg ctggtggcca ttttgttggc gatcccgcgt ccgacggtaa aagccagtaa
     8521 aggcaaaccg ctgccgtttc gcgcggtgct tgggcgcgtc tggctgtacg gtatggcgct
     8581 ggcactggct tccgccggat ttggcgtcat cgccaccttt atcacgctgt tttatgacgc
     8641 taaaggttgg gacggtgcgg ctttcgcgct gacgctgttt agctgtgcgt ttgtcggtac
     8701 gcgtttgtta ttccctaacg gcattaaccg tatcggtggc ttaaacgtag cgatgatttg
     8761 ctttagcgtt gagataatcg gcctgctact ggttggcgtg gcgactatgc cgtggatggc
     8821 gaaaatcggc gtcttactgg cgggggccgg gttttcgctg gtgttcccgg cattgggtgt
     8881 agtggcggta aaagcggttc cgcagcaaaa tcagggggcg gcgctggcaa cttacaccgt
     8941 atttatggat ttatcgcttg gcgtgactgg accactggct gggctggtga tgagctgggc
     9001 gggcgtaccg gtgatttatc tggcggcggc gggactggtc gcaatcgcgt tattactgac
     9061 gtggcgatta aaaaaacggc ctccggaaca cgtccctgag gccgcctcat catcttaaaa
     9121 cttactgaat aaccagcgta ttaatgatgt tttctgcggt ggtctgcgct ttttgctgat
     9181 cgtcagcggg cagcgtaatt tgcatggtca gcagttgatt acccacgtta cccagaataa
     9241 cggaagagta cgccgtctgg cctttcgcgg agataatact gtctaactgc tgcattttgt
     9301 gacctttcag ctcaatggct ttattggtta ccacttgcag ctgcggatcg cggctacgtt
     9361 gctgatcttc cagacgcttc gccagcaccg ccagatcttc tttcggatca tcgcccatga
     9421 tgacgatgac tgctttctgc ccggtggcgt cggaccagac atgcatgtta ttggcctgcg
     9481 ttcccagctt accgctctgg tcggtcatat ccgctggcag cgagaaactt aacttgccat
     9541 caagcaggtt gacgggattc ccggtagcgt tactttccgc gaccgaaccc tgcgccgtag
     9601 cgttagtgtc tttatcatca caggccgcaa gccccataac cagcaggcca attccgacat
     9661 atttaaccag attgcgcatt gacttcttcc tttcgataaa cggccataac ggctcattca
     9721 tccatcttat cacaactctg ataacgaacc tttaactcgc ctgcaaagcg ttgatttcgg
     9781 atttatctgc cagtcttttc aacagcatat tgagtaatac gccatacatt ggcaggaaga
     9841 aaacgatact gattaacact ttgaaacagt aatcgaccag cgcgatttcc atccagtgtt
     9901 cagccataaa ggcatccggg ctacgccaga aggcaatgaa gaaaaaggcc agcgtgtcgc
     9961 tgacgttacc gaacagtgtg gacgctgtcg gtgccagcca ccagcggcga ctctgacgca
    10021 ggcggttaaa aacgtgcacg tcgaggattt gccccagcgc gtaggccatg aaactggcgg
    10081 tggcgatacg ggcgacaaac aggttgaagt gggcgagtgc gccgaatccc tgccaggaac
    10141 ccatatagaa tagcgacgag atgacgtagg agattaataa cgcagggatc attaccgcga
    10201 agataatgcg tcgggccagc ggtgcgccaa aaatacgcac ggtcaggtcg gtagcaagaa
    10261 aaataaacgg aaagctaaac gcgccccagg tggtatggaa acccaaaatg gagacgggaa
    10321 gctgaaccag atagttactg gaggtgatca ccagcagatg aaataacgat aaccagaaca
    10381 acgccttata gcgttgagtt tgcgagaaaa cgttcatatt gtaccttttt gattaaccat
    10441 tggggtgagg gaacccaata cgtacgacac gtctgttacc ttaacataat aacgtgctta
    10501 cccttttttc gagccgccgc atgatactgc tttacgttga caatgcaatg gttaattttc
    10561 acgcaatcgt taacctagtt tgcttacgga ctcacagggc gtaaactagc gccgtttttt
    10621 taagtgatga gaagaaaatg accgatctct tttccagccc tgaccacaca ctcgacgcgc
    10681 ttggcctgcg ctgcccggaa ccggtgatga tggtgcgcaa aaccgtgcgc aatatgcagc
    10741 ctggcgaaac gttgctgatt atcgccgacg atccggccac tacccgcgat attcctgggt
    10801 tttgtacctt tatggaacac gaactggttg ctaaagagac ggatggactg ccttatcgtt
    10861 atttgattcg taaaggcggt tgataggggc tgattggctt cgatgccgcc ttttcccctc
    10921 accctaaccc tctccccaga ggggcgaggg gaccgatcgc gctcaatgtt gcgatcggtt
    10981 tgccttatct cctgcgcaac aatcttaacg cattcgctgt caccagcacc gtcgcccccg
    11041 tatctgccag cactgccagc cacaacccgg tcatccctaa cagcgtggtg acgaggaaga
    11101 tccctttcag ccccagcgca atagtgatgt tctggcggat attggcgtga gtggcgcgtg
    11161 ccagttcaat catttgcacc aggccgcgca ggtggttatg ggttaatgct gcgtcggcgg
    11221 tttccagcgc cacgtctgtg ccgctaccca ttgcaatccc gatggcggca gctttcatcg
    11281 ctggcgcgtc gttaataccg tcaccgacca tcgccagcgg cgcatgttga ttcagctcgg
    11341 tcaccgcttt gactttatct tccggcaaca ggcccgcttt aaactccagc cccagctccc
    11401 cggcaattgc cgccgctgcg cgtggattat cgccggtgag gatcacccct ttgacgccca
    11461 gcgcgttcag ttcactgatg gcagttgcag catcggcgcg cagggtatcc tgtaacgcaa
    11521 tgacaccaag cacgtcatcg ttacgtacta ccagcactac cgtttgcccg gcgctttcca
    11581 gttcgttaat taaaccagta aatgcatcag cgggatgttt cccggcagcg caaatcaata
    11641 cgcgctcacc gttaacctgc gcttcaatgc cagacccgac cagcgcccgc tgtgattcgg
    11701 cggtgggaat ggcgagttca gcaacctgtg cttcgcgtac gatggcttgc gccagtggat
    11761 gcgtcgcgcc ttgctcgacc gccgccgcca gtgtcagcag ttcagattca ctaatacccg
    11821 ttgccggatg aatcgcggta acgcgcggtt taccgacggt cagcgtaccg gttttatcaa
    11881 acgccacctg agtaacacga cccagctgtt ccagcgccgc tccgccttta atcaacgccc
    11941 cacgacgcgc tgccgccgcc agcccggagg taatcgccgc aggcgttgag ataactaacg
    12001 cacacgggca gccaatcagc agcagcgtca gccctttata aatccactcc tgccagctgg
    12061 cggcaaacag cagcggtggc accagcgtca ccagcagagc gacggccata atcgcgggcg
    12121 tatagatacg gctgaaacgg tcgataaacc gctcaatggg agcgcgacgc tcttcggctt
    12181 cttcgatcag tttcagaatc cggtcaatgg cgctggctcc cggttctgac agcacttcca
    12241 acgtcaccag acggtctacg ctggtggcac cagcagggac tttatcgccc gttgcgcgct
    12301 ccaccggaat ggattcgccg gtcagggcgc tttcatcaaa actggcaaac ggtgagagca
    12361 gtttaccgtc ggcaggcaaa cgcccacctg cggcgacttc aatcacatcg ccagggcgca
    12421 ggctgttaat cgccacctct tcccgctcac ccttacgcag gcgcgtggcg gtttctggtt
    12481 tcagcgccat taacgcgcta acgccctgac gcgcgcggct ggcggcccag ccttccagtc
    12541 gttcaccaat caaaaacagc agcaacacca tcgcagcttc agccgttgcg ccaataaaca
    12601 gtgcaccaat agcggctacg ctcattaagg tttcaatggc gaagtagctg ccggatttga
    12661 tcaaccgtaa tgcctgacga gcaatcgggt acagcccaac cagcgtggtc gcgataaacg
    12721 ccagttgccc gaacggatga ttgaactgct ccagacccca gctgattgcc atcatcacga
    12781 ttagcgtaat cagcggcaga ttctctttca ggcgtgatgc ttgcggttct tcggcggcct
    12841 gttcatcgcg cagggaatag cctgcttttt gcagcgcaga ttcaacttgt gcacgaatgt
    12901 cattgtcggc atcgaccacc agtttttcgg tggcgaacaa cacctgcacc tgattcacgc
    12961 ctgcaagctg gcgcacggca ttttctacct tgcgcgcaca ggcggcgcag tccatgccgc
    13021 tgactttcca gctatagcgg gtgccggaga cgttttcaga gagagttggc gtgctggaac
    13081 atgcgccgtc gcagcaacag tcgttggcgt tctgtaccgt ggttagcggt ttgaacgcag
    13141 caaattgagg ggctttcttg ccgtgattgt caggagtcga catggcatcc tccggttaag
    13201 ttttttctca ttaaccgaag gatacactct ggagtcgact ccagagtcaa gttttatcag
    13261 agatacagcg agcggacgat caggaagtga ccggcaaagt agcaggccgc agcaatcgcg
    13321 ttatccgcac ggaagcgtcg gcgatagtgg ctccccagcc agacaaagtt actgataaac
    13381 agcaacgaag cgccaacaaa cgcagagagc gccggagcgg tcggacggaa gaaccacagt
    13441 tcacctgcca gccacaccat caccagcgtc atgccgataa acgtgcagat aggccaacgg
    13501 tactcttcca ggcgcgtcca gataatcgcc agtaacagcg cacccagaac cagcagcacc
    13561 agtggtagag gccagaagaa agagagcgtc atctgactgg cgaaatagat ggtgtacagc
    13621 aggtgcgaga ggaaaaacgc gccgatggcg tacatcagac gttgacgtgg caacagggtt
    13681 agcgcatcgc ccagcagtga ggcgcacagc cctgccagca ccagatagct aatggcgtcg
    13741 aacatcggcg cttgccaggc cagtaacagc aggagaagaa gggttaacgg tttaaacacc
    13801 cagcgttgcc aggttggccc acgatacgat gcatccacag atagccatgc ggaaagacag
    13861 acagcgataa acgaccaaag catcttagtt ccttgaattc gttatttttt cgtaagcgga
    13921 atgcctacgg tcttgcttcc agtttagtgg cgagggtgga cggatgacaa caccataact
    13981 ggcagggtat gcttatttcc gcattttccg atgagggata aagatgagca aaccacctct
    14041 tttctttatt gttatcattg gcttaattgt cgtcgccgca tcgtttcgtt ttatgcaaca
    14101 gcgacgggaa aaagctgata atgatatggc tccgctccag caaaagctgg tggtggtgag
    14161 caacaagcgg gaaaaaccga ttaacgatcg ccgttcgcgc cagcaggaag tgactccggc
    14221 aggcaccagt atacgctatg aggcaagctt caaaccgcaa agcggaggaa tggagcagac
    14281 gtttcgcctc gacgcccagc agtaccacgc cctgacagtg ggcgataaag gtacgctgag
    14341 ctataaagga acgcgctttg tcagctttgt aggcgaacaa taaggttatt ttttaacttt
    14401 aaatttcttc tgccaggcca gcagttcaaa cacgccgaaa aggaaaatcc gtaccttttc
    14461 ggcggtggtc atctgcgggc catctttcgg taaagtggat ttcaatagcg ccagctgcat
    14521 accatgcatc agcacggtaa aaatcagcgc cacgttaacg aagatattca gcgggcgtgg
    14581 gaagggatgc accaggttga ggattaaaaa tccccaaacg cagagcatta acaaacgacc
    14641 aatattaatc agcatcactt tctccttgtg cttcgcgttg atacagccga taagccacct
    14701 gacccgccac tttttcccga tgtaatgacc agtttgctgg aacagtgggc agaccgtttt
    14761 cgacttcgct ttcgacataa atcagggctt cgtcagccag ccagccgtta tcttccagta
    14821 aatttatcgt ctcttctaac aagccacggc ggaatggtgg atcgacaaac acgatattat
    14881 gcggtgtgcc tttttgcgcc aggaatgaca tcgcgttgct gttcaccacg cgtgcattgc
    14941 ctgcttttag tgtcgccaga ttcttaatta actgctgaga aaccgcgcga tccatctcaa
    15001 tcaacgtggc ccccgcagcg tagcgcgaca acgcttccag ccccagtgcg ccgctcccgg
    15061 cgaagcaatc cagacattgg gcgtcaacaa tgaccggagc cagccagtta aacaacgttt
    15121 cgcgtacgcg gtcggtggtg gggcgcagac ctgggctatc aggaaccggg agtttacggc
    15181 ctcgccactg cccgccaata atgcggattt ggccgctgcc ggaatgattc ggttttttca
    15241 tgataaattg ctcaatccgc cagataacac atacttgcag gcggtgatgt gaattaagtt
    15301 aagtgataga ctatttcatc atttttttag ctgctatgta catagcgtta acgctgtgcc
    15361 atgaagcaac agcgaggagt gtagtcgcaa atggcgaaag aaaaaaaacg tggctttttt
    15421 tcctggctgg gctttggtca aaaagagcag accccggaaa aagagacaga agttcagaat
    15481 gaacaaccgg ttgtagaaga aatcgttcag gcgcaagaac ctgtgaaggc ttcggaacaa
    15541 gccgttgaag agcagccgca ggcgcatact gaagccgagg cggaaacttt tgctgccgac
    15601 gttgtggaag tcactgaaca ggttgctgaa agtgaaaaag cgcagcctga agcggaagtc
    15661 gttgcacagc cggaaccggt cgtagaagaa acgccggagc cagtggctat cgaacgtgaa
    15721 gagctgccgt tgccggaaga cgtcaacgcc gaagaggttt cgccagaaga gtggcaggct
    15781 gaagcggaaa ccgtagagat tgtcgaagcg gcggaagaag aagcggctaa agaagaaatc
    15841 accgacgaag agctggaagc acaggcgctg gctgccgaag cggcagaaga ggcggtgatg
    15901 gtggttcctc cggcagaaga agagcagccg gtggaagaaa tcgctcagga gcaggaaaaa
    15961 ccgaccaaag aaggtttttt cgcgcgcctg aaacgcagcc tgttaaaaac caaagaaaat
    16021 ctcggttccg gatttatcag cctgttccgc ggtaaaaaaa tcgacgatga tctgtttgaa
    16081 gagctggaag aacagctgtt gatcgccgat gtgggcgtgg aaaccacacg taaaataatc
    16141 accaatctga cggaaggcgc atcccgcaag cagcttcgtg atgccgaggc gctctatggc
    16201 ctgctgaaag aagagatggg cgagattctg gcgaaagtcg atgagccgct gaatgttgaa
    16261 ggtaaaacgc cgttcgtgat cctgatggtg ggcgtcaacg gtgtgggtaa aaccacgacg
    16321 attggtaagc tggcgcgtca gtttgagcag cagggtaaat cggtgatgct ggcggcaggc
    16381 gatactttcc gtgcggcagc ggttgaacag cttcaggtct ggggtcagcg caacaatatt
    16441 ccggtgattg cccagcatac tggtgcggat tccgcttctg ttatcttcga cgccattcag
    16501 gccgctaaag cgcgtaacat cgacgtcctg attgccgata ccgccggacg cctgcagaac
    16561 aaatcgcatc tgatggaaga gttgaagaaa atcgtccgcg tgatgaagaa actcgacgtt
    16621 gaagcgccgc atgaagttat gctgactatt gatgccagca ccgggcagaa cgcggtaagc
    16681 caggccaaac tgttccacga agctgttggc ttaaccggca tcacgctaac gaaactggac
    16741 ggcacggcga aaggcggggt aattttctcg gtggctgacc agtttggtat ccctatccgc
    16801 tacattggtg tcggcgaacg tattgaggat ttgcgtccgt ttaaggcgga cgactttata
    16861 gaggcacttt ttgcccgaga ggattaacaa tgattcgctt tgaacatgtc agcaaggctt
    16921 atctcggtgg gagacaggcg ctgcagggcg ttacgttcca tatgcagccg ggtgagatgg
    16981 cgtttctgac cggtcattcc ggcgcaggga aaagtaccct cctgaagctg atctgtggga
    17041 ttgagcggcc cagcgccggg aaaatctggt ttagcggcca tgacatcacg cgtctgaaaa
    17101 accgtgaagt tccgtttctg cgccgccaga ttggcatgat tttccaggat caccatctac
    17161 tgatggaccg tactgtctac gataacgtgg cgatcccgct gattatcgct ggtgccagcg
    17221 gtgacgatat tcgtcgccgg gtgtcggcgg cactggataa agtcgggcta ctggacaaag
    17281 cgaagaactt ccctattcag ctttctggcg gtgaacaaca gcgtgttggc attgcccgcg
    17341 cggtggtgaa caagcccgcg gtactgctgg cggacgaacc gactggtaac ctggacgacg
    17401 cgttgtcgga agggattcta cgtctgtttg aagagtttaa ccgcgttggg gtaaccgtat
    17461 tgatggcaac gcacgacatc aacctgattt cacggcgttc ctatcgcatg ctcaccctga
    17521 gcgatggtca cttgcatgga ggcgtgggcc atgaataagc gcgatgcaat caatcatatt
    17581 cggcagtttg gcgggcgtct ggatcgcttc cgtaaatcgg tcggtggctc tggcgacggc
    17641 ggtcgtaacg caccgaaacg cgcgaaatcc tcgccaaaac cggtaaatcg caaaaccaac
    17701 gttttcaacg aacaggtgcg ctatgccttc cacggcgcat tgcaggatct gaaaagcaaa
    17761 ccgttcgcca cgtttttaac ggtgatggtt atcgccatct ctctgacgct gcccagcgtc
    17821 tgttatatgg tgtacaaaaa cgttaaccag gcggcgacgc agtattatcc gtcaccgcaa
    17881 atcactgttt atctgcaaaa aacgctggac gatgacgccg ctgcgggtgt ggtggcacag
    17941 ttgcaggccg agcaaggcgt ggagaaagtg aattatcttt ctcgtgaaga cgcactgggt
    18001 gagttccgta actggtctgg ttttggtggt gcgctggata tgctggaaga aaacccgctt
    18061 ccggcagtgg cggtggtgat cccgaaactc gatttccagg gtacggagtc tctgaatacg
    18121 ctgcgtgatc gtatcacgca gattaacggc attgacgaag tgcggatgga tgacagctgg
    18181 tttgcccgtc tggcggcgtt gaccgggctg gtcgggcgcg tttcggcgat gatcggcgtg
    18241 ttgatggtgg cggcagtgtt cctcgtcatc ggtaacagtg tacgcctgag tatctttgct
    18301 cgtcgtgact ccattaacgt gcagaaactg attggtgcaa cggatggttt catcctgcgc
    18361 ccgttcctgt acggtggcgc attgctgggg ttttctggcg cattgttgtc actaattttg
    18421 tcagaaattc tggtactgcg attgtcatcg gcggttgcgg aagtggcaca ggttttcgga
    18481 acgaagtttg atatcaatgg cttatcgttc gatgaatgcc tgctattgct gctggtatgc
    18541 tcgatgattg gctgggtggc agcgtggctt gccacggtac aacatttacg ccactttacg
    18601 cctgaataat aaaagcgtgt tatactcttt ccctgcaatg ggttccgtag cagggaaaga
    18661 gaccccgttg tctcttcccg gtatttcatc tctatgtcac attttgtgcg taatttattc
    18721 acaagcttgc attgaacttg tggataaaat cacggtctga taaaacagtg aatgataacc
    18781 tcgttgctct taagctctgg cacagttgtt gctaccactg aagcgccaga agatatcgat
    18841 tgagaggatt tgaatgactg acaaaatgca aagtttagct ttagccccag ttggcaacct
    18901 ggattcctac atccgggcag ctaacgcgtg gccgatgttg tcggctgacg aggagcgggc
    18961 gctggctgaa aagctgcatt accatggcga tctggaagca gctaaaacgc tgatcctgtc
    19021 tcacctgcgg tttgttgttc atattgctcg taattatgcg ggctatggcc tgccacaggc
    19081 ggatttgatt caggaaggta acatcggcct gatgaaagca gtgcgccgtt ttaacccgga
    19141 agtgggtgtg cgcctggtct ccttcgccgt tcactggatc aaagcagaga tccacgaata
    19201 cgtcctgcgt aactggcgta ttgtcaaagt tgcgaccacc aaagcgcagc gcaaactgtt
    19261 cttcaacctg cgtaaaacca agcagcgtct gggctggttt aaccaggatg aagtcgaaat
    19321 ggtggcccgt gaactgggcg taaccagcaa agacgttcgt gagatggaat cacgtatggc
    19381 ggcacaggac atgacctttg acctgtcttc cgacgacgat tccgacagcc agccgatggc
    19441 accggtgctc tatctgcagg ataaatcatc taactttgcc gacggcatcg aagatgataa
    19501 ctgggaagag caggcggcaa accgtctgac cgacgcgatg caaggtctgg acgagcgtag
    19561 ccaggacatc atccgcgcgc gctggctgga cgaagacaac aagtccacgt tgcaggaact
    19621 ggctgaccgt tacggcgttt ccgctgagcg tgtgcgccag ctggaaaaga acgcgatgaa
    19681 aaaattgcgt gctgctatag aagcgtaatt tccgctatta agcagagaac cctggatgcg
    19741 agtccggggt ttttgttttt tgggcctctg taataatcaa tttcccctcc ggcaaaacgc
    19801 caatccccac gcagattgtt aataaactgt caaaatagct attccaatat cataaaaatc
    19861 gggtatgttt tagcagagta tgctgctaaa gcacgggtag tcatgcataa aacgaaataa
    19921 agtgctgaac aacaacatca caacacacgt aataaccaga agaatgggga ttctcaggat
    19981 gaacataaag ggtaaagcgt tactggcagg atgtatcgcg ctggcattca gcaatatggc
    20041 tctggcagaa gatattaaag tcgcggtcgt gggcgcaatg tccggtccgg tggcccagta
    20101 cggtgaccag gagtttaccg gcgcagagca ggcggttgcg gatatcaacg ctaaaggcgg
    20161 cattaaaggc aacaaactgc aaatcgtaaa atatgacgat gcctgtgacc cgaaacaggc
    20221 ggttgcggtg gcgaacaaag tcgttaacga cggcattaaa tacgtgattg gtcacctctg
    20281 ttcttcatca acgcagcctg cgtctgatat ctacgaagac gaaggcattt taatgatcac
    20341 cccagcggca accgcgccgg agctgaccgc ccgtagctat cagctgatcc tgcgcaccac
    20401 cggcctggac tccgaccagg ggccgacggc ggcgaaatat attcttgaga aagtgaaacc
    20461 gcagcgtatt gctatcgttc acgacaaaca gcaatacggc gaaggtctgg cgcgagcggt
    20521 gcaggacggc ctgaagaaag gcaatgctaa cgtggtgttc tttgatggta tcaccgccgg
    20581 ggaaaaagat ttctcaacgc tggtggcgcg tctgaaaaaa gagaatatcg acttcgttta
    20641 ctacggcggt tatcacccgg aaatggggca aatcctgcgt caggcacgcg cggcagggct
    20701 gaaaactcag tttatggggc cggaaggtgt ggctaacgtt tcgctgtcta acattgcggg
    20761 cgaatcagcg gaagggctgc tggtgaccaa gccgaagaac tacgatcagg ttccggcgaa
    20821 caaacccatt gttgacgcga tcaaagcgaa aaaacaggac ccaagcggcg cattcgtctg
    20881 gaccacctac gccgcgctgc aatctttgca ggcgggcctg aatcagtctg acgatccggc
    20941 tgaaatcgcc aaatacctga aagcgaactc cgtggatacc gtaatgggac cgctgacgtg
    21001 ggatgagaaa ggcgatctga aaggctttga gttcggcgta tttgactggc acgccaacgg
    21061 cacggcgacc gatgcgaagt aatcattaat cggcaacttt gggttgccgc caaattgcta
    21121 atatcgagta cgttgcttca tgccggatgc ggcgtaaacg ccttatccgg cctacaagat
    21181 ccaaagaaat cagtaaattg cagcacacat tgtaggcctg ataagcgtag cgcatcaggc
    21241 aatttctcgt tggtcatcac ttttgaaatc aaacttgacg attaacgctt ttcccagccg
    21301 ccctgttgcg ccgtaaatcc cagtgcctgc ataaacgccg tcatcacacc gcgatcttcc
    21361 acgcctgcat ccgccatcca ccagcatgaa acgccaggat tgttacgcaa aacctcttcc
    21421 agcagatatt gccccacacc gcgacgtcgg gtgacttccc gcacacgcag ggaatccagt
    21481 gctccctcgg tgccgcttaa ggttacccgt acggcagcga gcaggcgctc gttaaaacgc
    21541 gcggcgtaga tacggtggtt atcgtcaacc tgtaaagagg aaggggaata ctccggccag
    21601 atcttttgca ggtcaatccg gtcctggtcg ctaaagtttt ctaatcgaat gatggtcagc
    21661 ttcatgggta acccgtgtaa atcacaaaag tggaaccagt gtagcgaaat aatttaatcg
    21721 gaggctttct cttttttatt tcttttggca ggtgattaat tttttaacag caataattac
    21781 aaagttaaaa cattagagaa tgaaaaatgt ccagcataat cccctgaatg gtagtgaatt
    21841 attccgctct ttgtgccgtt attttatgct gacaaaggca cctttttctg tttatctatc
    21901 aataaattca gaatattatc tgttcttaat cgactgaaaa atagggattt taatcgctat
    21961 catcacaaaa tactgcgcta accccttaat cagacaggta aaaacagtgc agtataaaaa
    22021 aagaacagtc tgatttgtta acacataaaa acaaagcaac acaacatcac gaatggggat
    22081 ttttgactat gaaacggaat gcaaaaacta tcatcgcagg gatgattgca ctggcaattt
    22141 cacacaccgc tatggctgac gatattaaag tcgccgttgt cggcgcgatg tccggcccga
    22201 ttgcccagtg gggcgatatg gaatttaacg gcgcgcgtca ggcgattaaa gacattaatg
    22261 ccaaaggggg aattaagggc gacaagctgg ttggcgtgga atatgacgac gcctgcgacc
    22321 cgaaacaagc cgttgcggtc gccaacaaaa tcgttaatga cggcattaaa tacgttattg
    22381 gtcatctgtg ttcttcttct actcaacctg cgtcagatat ctatgaagat gaaggtattc
    22441 tgatgatctc gccgggagcg accaatccgg aactgaccca acgcggttat caacacatca
    22501 tgcgtactgc cgggctggac tcttcccagg ggccaacggc ggcaaaatac attcttgaga
    22561 cggtgaagcc ccagcgcatc gccatcattc acgacaaaca acagtatggc gaagggctgg
    22621 cgcgttcggt gcaggacggg ctgaaagcgg ctaacgccaa cgtcgtcttc ttcgacggca
    22681 ttaccgccgg ggagaaagat ttctccgcgc tgatcgcccg cctgaaaaaa gaaaacatcg
    22741 acttcgttta ctacggcggt tactacccgg aaatggggca gatgctgcgc caggcccgtt
    22801 ccgttggcct gaaaactcag tttatggggc cggaaggtgt gggtaacgca tcattgtcga
    22861 atattgccgg tgatgctgcc gaaggcatgt tggtcactat gccaaaacgc tatgaccagg
    22921 atccggcaaa ccagggcatc gttgatgcgc tgaaagcaga caagaaagat ccgtccgggc
    22981 cttatgtctg gatcacctac gcggcggtgc aatctctggc gactgccctt gagcgtactg
    23041 gcagcgatga gccgctggcg ctggtgaaag atttaaaagc taacggtgca aacaccgtga
    23101 ttgggccgct gaactgggat gaaaaaggcg atcttaaggg atttgatttt ggtgtcttcc
    23161 agtggcacgc cgacggttca tccacggcag ccaagtgatc atcccaccgc ccgtaaaatg
    23221 cgggcgggtt tagaaaggtt accttatgtc tgagcagttt ttgtatttct tgcagcagat
    23281 gtttaacggc gtcacgctgg gcagtaccta cgcgctgata gccatcggct acaccatggt
    23341 ttacggcatt atcggcatga tcaacttcgc ccacggcgag gtttatatga ttggcagcta
    23401 cgtctcattt atgatcatcg ccgcgctgat gatgatgggc attgataccg gctggctgct
    23461 ggtggcggcg ggattcgtcg gcgcaatcgt cattgccagc gcctacggct ggagtatcga
    23521 acgggtggct taccgcccgg tgcgtaattc taagcgcctg attgcgctta tttccgcaat
    23581 cggtatgtcc atcttcctgc aaaactacgt cagcctgacc gaaggttcgc gcgatgtggc
    23641 gctgcccagc ctgtttaacg gtcagtgggt ggtgggccat agcgaaaact tctctgcctc
    23701 tattaccacc atgcaggcgg tgatctggat tgtcaccttc ctcgccatgc tggcgctgac
    23761 gattttcatt cgctattccc gtatggggcg cgcctgtcgt gcctgcgcgg aagatctgaa
    23821 aatggcgagc ctgcttggca tcaacaccga ccgggtgatt gctttgacct ttgttattgg
    23881 cgcggcgatg gcggcagtgg ctggcgtact gctcggtcag ttctatggcg tcattaaccc
    23941 ctatatcggc tttatggccg ggatgaaagc ctttaccgct gcggtgctcg gtgggattgg
    24001 cagcattcca ggggcgatga ttggcgggct gatcttgggg attgcggagg cgctctcttc
    24061 tgcctatctg agtacggaat ataaggatgt ggtttcattt gccctgctga ttctggtgct
    24121 gctggtgatg ccgaccggta ttctgggtcg cccggaggta gagaaagtat gaaaccgatg
    24181 catattgcaa tggcgctgct ctctgccgcg atgttctttg tcctcgctgg cgtctttatg
    24241 ggcgtgcaac tggagctgga tggcaccaaa ctggtggtcg acagcgcttc ggatgtccgt
    24301 tggcagtggg tgtttatcgg cacggcggtg gtctttttct ttcagctttt gcgacctgct
    24361 ttccagaaag ggttgaaaag tgtttccgga ccgaagttta ttctgcccgc cattgatggc
    24421 tccacggtga agcagaaact gttcctcgtg gcgctgctgg tgcttgcggt ggcgtggccg
    24481 tttatggtgt cacgtgggac ggtggatatc gccactctga ccatgatcta cattatcctc
    24541 ggtctcgggc tgaatgtggt tgttggtctt tctggtctgc tggtgctggg gtacggcggt
    24601 ttttacgcca tcggcgctta cacctttgcg ctgctcaatc actattacgg cttgggcttc
    24661 tggacttgtc tgccgattgc cgggttaatg gcagcggcgg cgggcttcct gctcggcttt
    24721 ccggtgctgc gtcttcgtgg tgattatctg gcgatcgtta cccttggctt cggcgaaatt
    24781 gtgcgcatat tgctgctcaa taacaccgaa attaccggcg gcccgaacgg aatcagtcag
    24841 atcccgaaac cgactttctt cggccttgag ttcagccgta ccgctcgtga aggcggctgg
    24901 gacacgttca gtaatttctt tggcctgaaa tacgatccct ccgatcgcgt cattttcctg
    24961 tatctggtgg cgttgctgct ggtggtgcta agcctgtttg tcattaaccg cctgctgcgg
    25021 atgccgctgg ggcgtgcgtg ggaagcattg cgtgaagatg aaattgcctg ccgttcgctg
    25081 ggcttaagcc cgcgtcgtat caagctgacc gcctttacca tcagcgccgc gtttgccggt
    25141 tttgccggaa cgctgtttgc ggcgcgtcag ggctttgtca gcccggaatc cttcaccttt
    25201 gccgaatcgg cgtttgtgct ggcgatagtg gtgctcggcg gtatgggctc gcaatttgcg
    25261 gtgattctgg cggcaatttt gctggtggtg tcgcgcgaat tgatgcgtga tttcaacgaa
    25321 tacagcatgt taatgctcgg tggtttgatg gtgctgatga tgatctggcg tccgcagggc
    25381 ttgctgccca tgacgcgccc gcaactgaag ctgaaaaacg gcgcagcgaa aggagagcag
    25441 gcatgagtca gccattatta tctgttaacg gtctgatgat gcgcttcggc ggcctgctgg
    25501 cggtgaacaa cgtcaatctt gaactgtacc cgcaggaaat cgtctcgtta atcggcccta
    25561 acggtgccgg aaaaaccacg gtttttaact gcctgaccgg tttctacaaa cccaccggcg
    25621 gcaccatttt actgcgcgat cagcatcttg aaggtttacc ggggcagcaa attgcccgca
    25681 tgggcgtggt gcgcaccttc cagcatgtgc gtctgttccg tgaaatgacg gtaattgaaa
    25741 acctgctggt ggcgcagcat cagcaactga aaaccgggct gttctctggc ctgttgaaaa
    25801 cgccttcttt ccgtcgcgcc cagagcgaag cgctcgaccg cgccgccacc tggcttgagc
    25861 gcattggttt gctggaacac gccaaccgtc aggcgagtaa cctggcctat ggtgaccaac
    25921 gccgtctgga gattgcccgt tgcatggtga cgcagccgga gattttaatg ctcgacgaac
    25981 cggcggcagg tcttaacccg aaagagacga aagagctgga tgagctgatt gccgaactgc
    26041 gcaatcatca caacaccact atcttgttga ttgaacacga tatgaagctg gtgatgggga
    26101 tttcagaccg aatttacgtg gtcaatcagg ggacgccact ggcaaacggt acgccggagc
    26161 aaatccgtaa taacccggac gtgatccgtg cctatttagg tgaggcataa gatggaaaaa
    26221 gtcatgttgt cctttgacaa agtcagcgcc cactacggca aaatccaggc gctgcatgag
    26281 gtgagcttgc atatcaatca gggcgagatt gtcacgctga ttggcgcgaa cggggcgggg
    26341 aaaaccacct tgcttggtac gttatgcggc gatccgcgcg ccaccagcgg gcgaattgtg
    26401 tttgatgata aagacattac cgactggcag acggcgaaaa tcatgcgcga agcggtagcg
    26461 attgtcccgg aagggcgtcg cgtcttctcg cggatgacgg tggaagagaa cctggcgatg
    26521 ggcggcttct ttgccgaacg tgaccagttt caggagcgca taaagtgggt gtatgaactg
    26581 tttccacgtc tgcatgagcg ccgtgttcag cgggcgggca ccatgtccgg cggtgaacag
    26641 cagatgctgg cgattggtcg cgcgctgatg agcaatccgc gtttgctgct acttgatgag
    26701 ccatcgctcg gtcttgcgcc gattatcatc cagcaaattt tcgacaccat cgagcagctg
    26761 cgcgagcagg ggatgactat cttcctcgtc gagcagaacg ccaaccaggc gctaaagctg
    26821 gcggatcgcg gctacgtgct ggaaaacggc catgtggtgc tctccgatac cggcgacgtg
    26881 ctgctggcga acgaagcagt gagaagtgcg tatttaggcg ggtaataaca cgttgattga
    26941 taaggagtca aaagactcct ttgagacagg tgacaaatgt aaaattgcct gatgcgctgc
    27001 gcttatcagg cctactgggt gagttgcaat atattgaatt tgcacgatct tgtaggccgg
    27061 ataaggcgtt tacgccgcat ctggcatgaa acgatgagta atctgtagag tttgattcag
    27121 accttctatt tttccgctta tccgtgcccc atctcccatt ttccctcacc cacgccgtca
    27181 ccgccttgtc atctttctga caccttacta tcttacaaat gtaacaaaaa agttattttt
    27241 ctgtaattcg agcatgtcat gttaccccgc gagcataaaa cgcgtgaatt cgcgcattcg
    27301 gtacaacaag agagataaac gatgaaaccg ttacattata cagcttcagc actggcgctc
    27361 ggactggcgt taatggggaa tgcacaggca gtgacgacca ttccgttctg gcattctatg
    27421 gaaggggaac tgggtaaaga ggtggattct ctggcccaac gttttaacgc cgaaaatccg
    27481 gattacaaaa ttgtaccgac ctataaaggc aactacgaac agaatttaag cgcggggatt
    27541 gccgcatttc gtaccggcaa cgctccggct attttgcagg tttatgaagt tggcaccgcc
    27601 accatgatgg catcgaaagc cattaaaccg gtatatgacg tgtttaaaga ggcggggatt
    27661 caattcgatg agtcgcagtt tgtgccgacg gtttccggtt actactccga cagcaaaacg
    27721 ggccacttac tctcccagcc attcaacagc tcgacccccg ttctctatta caacaaagac
    27781 gccttcaaga aagcaggatt agacccggaa caaccgccga aaacctggca ggatctggcg
    27841 gactatgccg cgaaactgaa agcctccggc atgaagtgcg gctacgccag cggctggcag
    27901 ggctggatcc aactggaaaa ctttagcgcc tggaacggtc tgccgtttgc cagcaaaaac
    27961 aacggctttg acggcacgga cgcggtgctg gagttcaaca agccggagca ggtgaaacac
    28021 atcgccatgc tcgaggagat gaacaagaag ggcgacttca gctacgtcgg tcgtaaggat
    28081 gaatccaccg agaagttcta taacggtgat tgcgcgatga ccaccgcctc ttccggttct
    28141 cttgccaaca ttcgcgagta cgccaaattt aactacggcg taggcatgat gccttacgac
    28201 gccgatgcga aagatgcgcc acaaaacgcc attatcggcg gagccagcct gtgggtgatg
    28261 cagggtaaag ataaagaaac gtataccggt gtggcgaagt tcctcgattt cctcgcgaag
    28321 ccagaaaacg ctgccgagtg gcatcagaaa accggttatc tgccaatcac caaagcagcg
    28381 tatgacctga cccgtgagca gggcttttat gagaaaaacc caggggcgga taccgcgacg
    28441 cgtcagatgc tgaataagcc gccgttgccg ttcaccaaag ggctgcgtct gggcaacatg
    28501 ccgcagatcc gcgtgattgt ggatgaagag ctggagagcg tgtggaccgg taagaagaca
    28561 ccacagcagg cactggatac cgccgttgag cgtggaaatc agttgctgcg ccgctttgag
    28621 aaatcgacga agtcttaatc agtgtaatgt cggatgcgtt tcgcttatct gacctggcat
    28681 cgcgtgtagg ccggataagc gaagcgcatc cggcacagtt caggaattaa ccgtaatgtc
    28741 atcatcccgt ccggtgttcc gctcgcgctg gctgccttat ctgctggtcg cgccgcagct
    28801 catcatcacc gttatctttt ttatctggcc tgcgggcgaa gcgttgtggt actcgctaca
    28861 aagcgtcgat ccgtttggtt tctccagcca gtttgtcggc ctggataact tcgtcacgct
    28921 gttccatgac agctactatc tcgactcctt ctggacgacg ataaaattca gcacctttgt
    28981 caccgtcagc ggtttgctgg tatcgctgtt ctttgcggcg ctggtggagt acatcgtgcg
    29041 cggcagccgt ttctatcaaa ccttaatgtt gctgccttac gccgtggctc ccgccgttgc
    29101 cgccgtattg tggatcttcc tgtttaaccc cggtcgcggg ctgatcaccc attttctcgc
    29161 ggagttcggc tacgactgga accacgcgca aaacagcggt caggcaatgt ttctggtggt
    29221 gtttgcctca gtatggaagc aaatcagcta caacttcctg ttcttctatg ccgcgctgca
    29281 atccattccc cgttcgttga tcgaagccgc agccatcgac ggtgcagggc cgattcgccg
    29341 cttctttaag attgcgctgc cgcttatcgc cccggtgagt ttcttcctgc tggtagtgaa
    29401 cctggtgtat gccttcttcg acaccttccc ggtgatcgac gccgccacgt ccggcgggcc
    29461 ggttcaggcc accacgacgc tgatttataa gatctaccgc gaaggtttta ccggactgga
    29521 tctggcttcg tctgccgcac agtcggtggt gttgatgttc ctcgtcatcg tgctgacggt
    29581 ggtgcagttc cgctatgttg aaagcaaggt gcgttaccaa tgattgagaa ccgtccgtgg
    29641 ctgacgatat tcagccatac catgctgatc ctcgggatcg cggtgatcct cttcccgctg
    29701 tacgtggcgt ttgtcgcggc gacgctggat aaacaggccg tctatgccgc gccgatgacg
    29761 ctcatccccg gcacacatct gctggaaaac atccacaaca tctgggtgaa cggggtaggc
    29821 acgaatagcg cgccgttctg gcggatgttg cttaacagct ttgtgatggc gttcagcatt
    29881 acgctcggca aaattaccgt ctcgatgctc tcggcatttg ccattgtctg gtttcgtttt
    29941 ccgctacgta acctcttctt ctggatgatt tttatcaccc tgatgctgcc ggttgaagta
    30001 cgtatcttcc cgacggtgga agtcatcgcc aacctgcaga tgctcgacag ctacgccggt
    30061 ttaacgctgc cgctgatggc ctcggcgacc gctactttcc tgttccgcca gttctttatg
    30121 acgctgccgg atgagctggt ggaagccgcg cggatcgacg gcgcatcgcc aatgcgcttc
    30181 ttttgcgaca tcgtttttcc gctctccaaa actaatctgg cggcgctgtt tgtgatcacc
    30241 tttatctacg gctggaatca gtatttgtgg ccgttgttga ttattaccga tgtggatctc
    30301 ggcaccaccg tggcagggat caaagggatg atcgctacag gcgaaggcac cacggaatgg
    30361 aactcagtga tggcggcgat gttgttaacg cttatccctc cggtggtgat tgttttagtg
    30421 atgcagcgtg ccttcgtgcg cggcctggtc gatagtgaga aataagatgg caggactgaa
    30481 attacaggca gtaaccaaaa gctgggatgg taaaacccag gtcattaaac cgctgaccct
    30541 tgatgtggcg gatggcgaat ttatcgtgat ggtcgggccg tctggctgcg ggaaatcgac
    30601 gctgctgcgc atggttgccg ggctggagcg ggtgacagaa ggcgatatct ggatcaacga
    30661 ccagcgcgtg actgaaatgg agccaaaaga tcgcgggatt gcgatggtgt tccagaacta
    30721 cgcgctttat ccgcatatga gtgtcgaaga aaacatggcg tgggggctga aaattcgcgg
    30781 catgggcaag cagcaaattg ccgagcgcgt taaagaagcg gcgcgcattc tggagctgga
    30841 cggtctgctc aaacgtcgcc cgcgcgagct ttccggcggt cagcgccagc gtgtggcgat
    30901 gggccgcgcg attgtgcgcg atccggcggt gttcctgttt gatgagccgc tctctaacct
    30961 cgatgccaag ctgcgcgtgc agatgcgtct tgaactgcaa cagttgcacc gtcgcctgaa
    31021 aacgacttca ctctacgtta ctcacgatca ggttgaagcg atgacgctcg cccagcgagt
    31081 aatggtgatg aacggcggtg ttgccgaaca gattggcaca ccagttgaag tctacgaaaa
    31141 gcccgccagc ctgtttgtag cgagttttat cggcagtccg gcgatgaacc tgctgacagg
    31201 ccgcgtgaat aacgaaggca cgcatttcga actggacggc ggtattgagc tgccgctaaa
    31261 cggtggctac cgtcagtatg ccgggcgtaa aatgactctc ggcattcgcc cggaacatat
    31321 tgcgctaagc tcgcaggcag aaggcggcgt accgatggtg atggacacgc tggagatcct
    31381 cggcgcagat aacctggcgc acggacgctg gggcgagcag aagctggtgg tgcgactggc
    31441 gcatcaggag cgcccgacgg caggcagcac gctgtggctg catctggcgg aaaatcagct
    31501 gcatcttttt gatggtgaaa caggacaacg agtatgagta actggcctta tccccgcatc
    31561 gtcgctcatc gtggcggcgg taagctggcc ccggaaaaca ccctggcggc aatcgacgtc
    31621 ggggcaaaat acggtcataa gatgatcgaa tttgacgcga agttatcgaa agatggcgag
    31681 atcttcctgc ttcatgacga caatctcgaa cgcaccagca acggctgggg cgtcgcgggt
    31741 gaactgaact ggcaggattt actgcgcgtg gatgcgggca gttggtacag caaagcgttt
    31801 aaaggtgagc cgctgccgtt gctttcgcag gtggcggaac gctgtcgtga acacgggatg
    31861 atggcgaata tcgaaatcaa acccaccact ggcactggac cattaacggg caaaatggtg
    31921 gcgctggcgg cacgccaact gtgggccggt atgacgccgc cgctgctgtc atcgtttgag
    31981 attgatgctt tagaagccgc acaacaggca gtaccggaac tgccgcgcgg tttgttgctg
    32041 gatgagtggc gcgacgactg gcgcgaactg accgcgcggc tgggctgcgt ctctattcat
    32101 ctcaatcata agttactcga taaagtgcga gtgatgcagt tgaaagacgc cggactgcgg
    32161 attctggttt ataccgtcaa taaaccccag cgcgcggcag agttgctgcg ctggggcgtg
    32221 gattgcatct gtaccgatgc gattgacgtg attggtccga actttacggc ccaatagttt
    32281 tcaacggaat gtcaggctgc ggcgtgctgg gctgattcag catgtcgccg tttctcctct
    32341 ccggcagcat atgctgctga ttcaacgaac tatccggatt acggttgctg tttaacatcc
    32401 cgccgttggt gttgggcagc atttgctgcc gggcgggatt tcgctccccc ggctgtgact
    32461 gcaacacccg ctgagaatta ttgtttatct ggttttctaa atgctgctgt tgcaactgag
    32521 tttgcgtttt cagttgctga ttcagcatcc ctttttgctg gatttgctga gtctgcatct
    32581 gggtttgcat ccgctgctgg ctgggtatct gataccccgg ctggttaggg ttgttcagag
    32641 tattaatggg ctgtgcaaag ccgacaaacg gcaggagtgc cgtaagaatc agaagtcgtt
    32701 tcatcgcgta tcctcctctg aagatatcct ttaagtttac tcgcttcccg acaaaacgat
    32761 gattaattca gagttatata ccaggcttag ctggggttgc cccttaatct ctggagaata
    32821 acgatgataa aaccgacgtt tttacgccgg gtggccattg ctgctctgct ctcaggaagt
    32881 tgttttagcg ccgccgccgc gcctcctgcg ccgcccgtct cgtatggtgt ggaggaagat
    32941 gtcttccacc cggtacgcgc gaaacaggga atggtagcgt ctgtggacgc cactgccact
    33001 caggtggggg tggatattct caaggagggc gggaatgccg ttgatgccgc cgtggcggtg
    33061 ggctacgcgc tggcggtaac gcatccgcag gcagggaatc tgggcggtgg tggttttatg
    33121 ttaatccgct cgaaaaatgg caataccacg gctatcgatt tccgcgaaat ggcacccgcc
    33181 aaagcgaccc gcgatatgtt cctcgatgat cagggcaacc cggacagcaa aaaatcactc
    33241 acttcgcatc tggcttccgg cacaccgggt acggtagcag gtttctcgct ggcgctggat
    33301 aaatacggca ccatgccgct gaacaaagtc gtgcagcccg cgtttaaact ggcacgcgat
    33361 ggttttatcg ttaacgacgc gctggctgac gatctcaaaa cctacggtag cgaagtgttg
    33421 ccgaatcacg aaaacagtaa agctatcttc tggaaagagg gcgagccgct gaaaaagggc
    33481 gacacgctgg tgcaggcgaa cctggcaaag agcctggaga tgattgctga aaacggcccg
    33541 gacgaattct ataaaggcac gattgcggaa cagatcgccc aggagatgca gaaaaacggt
    33601 ggcttgatca ctaaagaaga tttagcagcc tataaagcgg tcgaacgcac tccgataagc
    33661 ggcgattatc gcgggtatca ggtttactcc atgccaccgc catcctccgg cgggatccat
    33721 atcgtacaaa tcctcaatat tctggaaaac ttcgatatga agaaatacgg ctttggcagc
    33781 gccgatgcga tgcaaatcat ggcagaagcg gagaaatacg cctacgccga ccgctcggaa
    33841 tatcttggcg acccggattt tgtcaaagta ccgtggcagg cgctgaccaa taaagcctat
    33901 gccaaatcta ttgccgatca aattgatatc aataaagcga agccatccag cgaaattcgc
    33961 cccggcaagc ttgcgcctta tgagagtaat caaactaccc attactcagt ggtggataaa
    34021 gatggtaacg cggtggcggt gacctatacg ctgaacacca ccttcggtac gggcattgtc
    34081 gcgggcgaga gcggtattct gcttaataac cagatggatg atttctccgc caaaccgggc
    34141 gtaccgaacg tttacgggct ggtgggcggt gatgccaacg ccgtcgggcc gaacaaacgc
    34201 ccgctgtcgt cgatgtcgcc gaccattgtg gtgaaagacg gtaaaacctg gctggttacc
    34261 ggtagcccag gcggtagccg gatcatcact acagtgctgc aaatggtggt gaatagcatc
    34321 gattatggct tgaacgtcgc cgaagcgacc aatgcgccgc gtttccacca tcagtggttg
    34381 tcggacgagc tgcgtgtcga aaaagggttt agcccggata cgctcaagct gctggaagca
    34441 aaaggtcaga aagtggcgct gaaagaggcg atgggcagta cacaaagcat tatggttggg
    34501 ccggacggtg agttgtacgg cgcatccgac ccgcgctcgg tggatgattt aacggcgggg
    34561 tactaaggtt agcggccctc ttcgtgggaa gagggctatt ttgtcagggc aagccgaagg
    34621 tagccttttt tatttcgtaa tcctgtagat attcttccag cggttttgcc gttcccagag
    34681 aatgaatttc accactgtct ttatcaataa taaaaggtgc gttaccagct aagcgcgcgg
    34741 cctcatctcc agtttcgaga aattctcgtg cttcgaaaca gaaataccag ccctggctaa
    34801 agcgtccatg tagagtaatg acgaccggga gatctgcatc atcaaggtaa tggttcgctt
    34861 tcgcgaatgc gtcgtgataa gtaatcataa ttataataaa tattattgtt gagtgttata
    34921 ttattattcc tgtgtgatac attgagcaaa gacgcgttca tcttcgtcaa agatattatt
    34981 aaatgctggt tttgaaaaaa gttcatcgga taagatatag tcacgaaata agtatctgct
    35041 aatattttat gatttctttt tcagaacgtc gaacgggatt ttcttattta agatatcaga
    35101 atcttatgat tcgggtaaaa ttctaaataa atcaacatgt cattaaaatc atcatagcca
    35161 ttagctattt cggctaaaat agagactaca tgtcttcggt ccatctcact taaggagtgt
    35221 agttccgttg taagtttttc catagcttgc actgctaaat ttcgaacaag gaattttctg
    35281 ctggtaatct ctaaaaagat ggcatggttt acaatgattt ttgtttcctt ttgattatta
    35341 tgaacaactg tccatgattt cgtttaagaa tgaagagaaa tcactaaacg aactgaatat
    35401 attttctgtg ccaatattat ctctaatttc aaaaaagtta cttttaatgt cataagtaaa
    35461 tattgaaatg ctataatccc cgatcactaa ccgttcttgt agatcagggt ttatgaaatc
    35521 atcattattt ctataaaatt catttacggc aaaaaggttt ttaactga
//
LOCUS       DAPHKZ010000040        35243 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.040, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000040 DAPHKZ010000000
VERSION     DAPHKZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35243
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.040"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            51..1304
                     /locus_tag="RH288_002037"
     CDS             51..1304
                     /locus_tag="RH288_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4031087.1"
                     /translation="MSRTTTVDGAPASDTDKQSISQPNQFIKRGTPQFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAV
                     VGLLSLAYLTGTWSSPKAGTMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNG
                     VGAFIALMLVIALLVGTRLHRRLHA"
     gene            1701..2036
                     /locus_tag="RH288_002038"
     CDS             1701..2036
                     /locus_tag="RH288_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416114.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HDV4031088.1"
                     /translation="MKKQIEGMTMKKVLALVVAAAMGLSSAAFAAETTTTPAPTATTT
                     KAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQP
                     AKPAAQPAA"
     gene            2129..2212
                     /locus_tag="RH288_002039"
     CDS             2129..2212
                     /locus_tag="RH288_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031089.1"
                     /translation="MVGRYRFEFILIILILCALIAARFYLS"
     gene            2312..3133
                     /locus_tag="RH288_002040"
     CDS             2312..3133
                     /locus_tag="RH288_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HDV4031090.1"
                     /translation="MRTTIAVVLGAISLTSAFVFADKPDVARSANDEVSTLFFGHDDR
                     VPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRF
                     VSNKGLWRYEIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
                     LPLFEGDKAALTAALKAAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDT
                     LPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK"
     gene            complement(3172..3501)
                     /gene="mdtI"
                     /locus_tag="RH288_002041"
     CDS             complement(3172..3501)
                     /gene="mdtI"
                     /locus_tag="RH288_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HDV4031091.1"
                     /translation="MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAG
                     MIMVKLA"
     gene            complement(3488..3853)
                     /gene="mdtJ"
                     /locus_tag="RH288_002042"
     CDS             complement(3488..3853)
                     /gene="mdtJ"
                     /locus_tag="RH288_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HDV4031092.1"
                     /translation="MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLS
                     YIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLI
                     KSGTRKARKPELEVNHGAV"
     gene            4265..5299
                     /gene="tqsA"
                     /locus_tag="RH288_002043"
     CDS             4265..5299
                     /gene="tqsA"
                     /locus_tag="RH288_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2 transporter TqsA"
                     /protein_id="HDV4031093.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIA
                     VILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLLAYLGSALNELTRTLPQYRNSIM
                     TPLQALEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLF
                     MLLEVPQLPGKFQQMMARPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTAGGQSI
                     AVLLSDLNKE"
     gene            complement(5324..6712)
                     /gene="pntB"
                     /locus_tag="RH288_002044"
     CDS             complement(5324..6712)
                     /gene="pntB"
                     /locus_tag="RH288_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HDV4031094.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
                     HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGD
                     AKASVDAILKAL"
     gene            complement(6723..8255)
                     /gene="pntA"
                     /locus_tag="RH288_002045"
     CDS             complement(6723..8255)
                     /gene="pntA"
                     /locus_tag="RH288_002045"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HDV4031095.1"
                     /translation="MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLAS
                     FDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELM
                     QKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMK
                     AGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQAAQKAAPEVKTE
                     EKCTCSPWRKYALMALAIILFGWMASVAPKEFLGHFTVFALACVVGYYVVWNVSHALH
                     TPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFR
                     KN"
     gene            8779..9723
                     /locus_tag="RH288_002046"
     CDS             8779..9723
                     /locus_tag="RH288_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV4031096.1"
                     /translation="MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTG
                     RFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSGNWRVVADLYKADAEKAEETSNR
                     VINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
                     NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTA
                     SPSSEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTE
                     VSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK"
     gene            9909..11291
                     /locus_tag="RH288_002047"
     CDS             9909..11291
                     /locus_tag="RH288_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV4031097.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWG
                     ITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASL
                     WLTNICVQICLELIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIA
                     SVPATWMLVG"
     gene            11328..12050
                     /gene="folM"
                     /locus_tag="RH288_002048"
     CDS             11328..12050
                     /gene="folM"
                     /locus_tag="RH288_002048"
                     /EC_number="1.5.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydromonapterin reductase"
                     /protein_id="HDV4031098.1"
                     /translation="MGKTQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAI
                     DGLINAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGAPLADVL
                     ACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALD
                     NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVD
                     YLLTSCFVTGRSFPLDGGRHLR"
     gene            complement(12047..12382)
                     /locus_tag="RH288_002049"
     CDS             complement(12047..12382)
                     /locus_tag="RH288_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HDV4031099.1"
                     /translation="MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIEALRATIIFSMWSIIPYFVYLVSLWYFTGMMRLPAAFVGSVACWGISAWV
                     LIICWIKLH"
     gene            12511..13230
                     /gene="rstA"
                     /locus_tag="RH288_002050"
     CDS             12511..13230
                     /gene="rstA"
                     /locus_tag="RH288_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HDV4031100.1"
                     /translation="MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRE
                     NPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQNEQATLTKGLQETSLTPYKALHFGTLTIDPINRVVTLANTEI
                     SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAA
                     EPYRIKTVRNKGYLFAPHAWE"
     gene            13234..14535
                     /gene="rstB"
                     /locus_tag="RH288_002051"
     CDS             13234..14535
                     /gene="rstB"
                     /locus_tag="RH288_002051"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HDV4031101.1"
                     /translation="MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMN
                     SSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVA
                     LDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPH
                     WQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGVAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELH
                     LSEPDLPLWLSTHLADIQAVTPDKTVRIKTLVQGHYAALDMRLMERVLDNLLNNALRY
                     CHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLA
                     IVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA"
     gene            14611..15540
                     /gene="tus"
                     /locus_tag="RH288_002052"
     CDS             14611..15540
                     /gene="tus"
                     /locus_tag="RH288_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HDV4031102.1"
                     /translation="MARYDLVDRLNTTFRQMEQELAIFAAHLEQHKLLVARVFSLPEV
                     KKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLT
                     VLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQD
                     IAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGE
                     LLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD"
     gene            complement(15537..16940)
                     /gene="fumC"
                     /locus_tag="RH288_002053"
     CDS             complement(15537..16940)
                     /gene="fumC"
                     /locus_tag="RH288_002053"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HDV4031103.1"
                     /translation="MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSL
                     IHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQS
                     NMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
                     IPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYS
                     LPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALT
                     MLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIE
                     PNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEF
                     DSWVRPEQMVGSMKAGR"
     gene            complement(17083..18729)
                     /gene="fumB"
                     /locus_tag="RH288_002054"
     CDS             complement(17083..18729)
                     /gene="fumB"
                     /locus_tag="RH288_002054"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HDV4031104.1"
                     /translation="MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKEL
                     LIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIW
                     IEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK"
     gene            18928..20103
                     /gene="manA"
                     /locus_tag="RH288_002055"
     CDS             18928..20103
                     /gene="manA"
                     /locus_tag="RH288_002055"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416130.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HDV4031105.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKS
                     SSRVQNAAGDIVSLRDVIESDKSTLLGEAVAKRFGELPFLFKVLCAAQPLSIQVHPNK
                     HNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQP
                     VAGAHPAIAHFLQQPDAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIR
                     LISEFYPEDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEAKPANQLLTQPVKQGAELDFPIPVDDFAFSLHDLSDKETT
                     ISQQSAAILFCVEGDATLWKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL"
     gene            20204..21712
                     /locus_tag="RH288_002056"
     CDS             20204..21712
                     /locus_tag="RH288_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HDV4031106.1"
                     /translation="MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQL
                     KLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKENPWIKSGQSVIFNESVDHGPFP
                     LAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
                     PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLK
                     TDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPELY
                     QEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLA
                     QEVDRSVKSLDAKLTIPVDMATEFMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFR
                     LTTLQDNTITTSLQYANGQITLNGQKMSLEDFVGMFAMPALNVPAVPAIPQQ"
     gene            complement(21938..23203)
                     /gene="uidC"
                     /locus_tag="RH288_002057"
     CDS             complement(21938..23203)
                     /gene="uidC"
                     /locus_tag="RH288_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416132.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide uptake porin UidC"
                     /protein_id="HDV4031107.1"
                     /translation="MRKIVAMAVICLTAASGLTSAYAAQLADDEAGLRIRLKNELRRA
                     DKPSAGAGRDIYAWVQGGLLDFNSGYYSNIIGVEGGAYYVYKLGARADMSTRWYLDGD
                     KSFGFALGAVKIKPSENSLLKLGRFGTDYSYGSLPYRIPLMAGSSQRTLPTVSEGALG
                     YWALTPNIDLWGMWRSRVFLWTDSTTGIRDEGVYNSQTGKYDKHRARSFLAASWHDDT
                     SRYSLGASVQKDVSNQIQSILEKSIPLDPNYTLKGELLGFYAQLEGLSRNTSQPNETA
                     LVSGQLTWNAPWGSVFGSGGYLRHAMNGAVVDTDIGYPFSLSLDRNREGMQSWQLGVN
                     YRLTPQFTLTFAPIVTRGYESSKRDVRIEGTGILGGMNYRVSEGPLQGMNFFLAADKG
                     REKRDGSTLGDRLNYWDVKMSIQYDFMLK"
     gene            complement(23242..24615)
                     /gene="uidB"
                     /locus_tag="RH288_002058"
     CDS             complement(23242..24615)
                     /gene="uidB"
                     /locus_tag="RH288_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide transporter"
                     /protein_id="HDV4031108.1"
                     /translation="MNQQLSWRTIVGYSLGDVANNFAFAMGALFLLSYYTDVAGVGAA
                     AAGTMLLLVRVFDAFADVFAGRVVDSVNTRWGKFRPFLLFGTAPLMIFSVLVFWVPTD
                     WSHGSKVVYAYLTYMGLGLCYSLVNIPYGSLATAMTQQPQSRARLGAARGIAASLTFV
                     CLAFLIGPSIKNSSPEEMVSVYHFWTIVLAIAGMVLYFICFKSTRENVVRIVAQPSLN
                     ISLQTLKRNRPLFMLCIGALCVLISTFAVSASSLFYVRYVLNDTGLFTVLVLVQNLVG
                     TVASAPLVPGMVARIGKKNTFLIGALLGTCGYLLFFWVSVWSLPVALVALAIASIGQG
                     VTMTVMWALEADTVEYGEYLTGVRIEGLTYSLFSFTRKCGQAIGGSIPAFILGLSGYI
                     ANQVQTPEVIMGIRTSIALVPCGFMLLAFVIIWFYPLTDKKFKEIVVEIDNRKKVQQQ
                     LISDITN"
     gene            complement(24612..26423)
                     /gene="uidA"
                     /locus_tag="RH288_002059"
                     /pseudo
     CDS             complement(24612..26423)
                     /gene="uidA"
                     /locus_tag="RH288_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
     gene            complement(26814..27404)
                     /gene="uidR"
                     /locus_tag="RH288_002060"
     CDS             complement(26814..27404)
                     /gene="uidR"
                     /locus_tag="RH288_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator UidR"
                     /protein_id="HDV4031109.1"
                     /translation="MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAIS
                     PGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQR
                     ALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLL
                     DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS"
     gene            complement(27625..28392)
                     /gene="hdhA"
                     /locus_tag="RH288_002061"
     CDS             complement(27625..28392)
                     /gene="hdhA"
                     /locus_tag="RH288_002061"
                     /EC_number="1.1.1.159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HDV4031110.1"
                     /translation="MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN
                     ADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPK
                     PFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYA
                     SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRL
                     GQPQDIANAALFLCSPAASWVSGQILTVSGGGVQELN"
     gene            complement(28504..29532)
                     /gene="malI"
                     /locus_tag="RH288_002062"
     CDS             complement(28504..29532)
                     /gene="malI"
                     /locus_tag="RH288_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mal regulon transcriptional regulator MalI"
                     /protein_id="HDV4031111.1"
                     /translation="MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAA
                     IEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHG
                     GKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVD
                     TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSD
                     WVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDR
                     YFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGITLADRMMQKITHEETHSRNLII
                     PARLIAAK"
     gene            29707..31299
                     /gene="malX"
                     /locus_tag="RH288_002063"
     CDS             29707..31299
                     /gene="malX"
                     /locus_tag="RH288_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IICB"
                     /protein_id="HDV4031112.1"
                     /translation="MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSS
                     HDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGF
                     IGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
                     LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINS
                     AGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSC
                     PTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVV
                     GGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHG
                     LSTKWYMVPVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGY
                     NVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQV
                     VIGPQVQSVKDEMAGLMHTVQA"
     gene            31309..32481
                     /gene="malY"
                     /locus_tag="RH288_002064"
     CDS             31309..32481
                     /gene="malY"
                     /locus_tag="RH288_002064"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional maltose regulon transcriptional
                     repressor/cystathionine beta-lyase MalY"
                     /protein_id="HDV4031113.1"
                     /translation="MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAP
                     CIIEALNQRLMHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDSQTVVYGPSVIYMVSE
                     LIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLAK
                     PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWS
                     NVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTA
                     HIAAYQQGAPWLDALRIYLKDNLTYIADKMNAAFPELNWQIPQSTYLAWLDLRPLNID
                     DNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVR"
     gene            32585..33586
                     /gene="add"
                     /locus_tag="RH288_002065"
     CDS             32585..33586
                     /gene="add"
                     /locus_tag="RH288_002065"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDV4031114.1"
                     /translation="MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLI
                     PHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSPG
                     YMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
                     DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASIN
                     TDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK"
     gene            complement(33620..34660)
                     /locus_tag="RH288_002066"
     CDS             complement(33620..34660)
                     /locus_tag="RH288_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDV4031115.1"
                     /translation="MSDNIRVGLIGYGYASKTFHAPLIAGTPGLELAVISSSDETKVK
                     ADWPTVTVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELDALAKSLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTRVEGEERVEETLLTVPGNYPAYYAAIRDALNGDGENPVPASQAIQVMELIELGI
                     ESAKHRATLCLA"
     gene            34903..35028
                     /gene="blr"
                     /locus_tag="RH288_002067"
     CDS             34903..35028
                     /gene="blr"
                     /locus_tag="RH288_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HDV4031116.1"
                     /translation="MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK"
BASE COUNT         8672 a         9134 c         8522 g         8915 t
ORIGIN      
        1 ctaccctatg tataagcctg atctacaggc atatttagca aggatttcaa gtgagccgta
       61 ctacaactgt tgatggcgct ccggcaagcg acactgacaa gcaaagcatt tctcagccaa
      121 atcaatttat taaacgcggt acgccgcaat ttatgcgcgt caccctggcg ctgttctctg
      181 ccggactggc aacatttgca cttctctatt gtgtgcagcc tatccttccg gtgctttcgc
      241 aggagtttgg cttaaccccc gcgaacagta gtatttcact gtccatttcc acggcgatgt
      301 tggctattgg tttgctgttt actggcccgc tatccgatgc cattggtcgc aaaccagtga
      361 tggtcacggc gctactgttg gcctccattt gtacgttact ttcgacaatg atgaccagct
      421 ggcacggcat tttgattatg cgcgccttga ttgggctttc gttaagtggc gtggcagctg
      481 ttggcatgac ttatcttagc gaggaaatcc atcccagttt cgtggccttt tcaatggggt
      541 tgtatatcag cggcaactca attggcggca tgagcggacg cttaattagc ggtgtcttca
      601 cggacttttt caactggcga attgctctgg cggcaatcgg ttgtttcgcg ctggcctcgg
      661 cgttgatgtt ctggaaaatc ctccctgaat cacgccattt tcgcccgact tcgctgcgcc
      721 ctaagacgtt gtttatcaac tttcgtctgc actggcgtga ccggggatta ccgttattgt
      781 tcgcagaagg ctttttgctg atggggtcgt tcgtcacgct gtttaattac atcggctatc
      841 ggttgatgct ctccccctgg catgtcagtc aggccgtggt tggcttatta tcgctggctt
      901 atttgaccgg tacatggagc tcacccaaag ccggaaccat gaccacccgc tatgggcgtg
      961 gtccagtgat gttgttttcg acgggggtta tgctgtttgg tttactgatg accttattca
     1021 gctcgctgtg gctgatcttt gccggaatgt tactcttctc agcaggattc ttcgcagccc
     1081 actcagtagc cagcagctgg atcggccccc gcgcaaaacg cgctaaaggc caggcctcct
     1141 cgctgtatct gttcagttac tatctggggt cgagtattgc cgggacgctg ggtggtgttt
     1201 tctggcataa ctatggctgg aacggcgtcg gcgcatttat tgctctgatg ctggtcattg
     1261 ctctgctggt cgggacgcgt ttgcatcgtc gtctgcacgc ctgaaaaata agtccggact
     1321 gcggtaaata cccgtccgga cttattgcca gctcaaacca acgttaatag ccatcctaaa
     1381 atagacgaag cgccagccaa ttcccgcagc gcgtctagcg tcatcaggat tataagtacc
     1441 caaataaacg gattcatttt gctgtgtgtc atttattact gatgcgcagt tattctactg
     1501 ctttgtaagt agtaaaatag ttaacccgat caagactact attattggta gctaaatttc
     1561 ccttaagtca caatacgtta ttatcaacgc tgtaatttat tcagcgtttg tacatatcgt
     1621 tacacgctga aaccaaccac tcacggaagt ctgccattcc cagggatata gttatttcaa
     1681 cggccccgca gtggggttaa atgaaaaaac aaattgaggg tatgacaatg aaaaaagtat
     1741 tagctctggt tgttgccgct gctatgggtc tgtcttctgc cgcctttgct gcagagacta
     1801 cgaccacacc tgctccgact gcgacgacca ccaaagcagc gccggcgaaa actacacatc
     1861 ataaaaaaca gcataaagca gcacctgccc agaaagcgca ggcggctaaa aagcatcata
     1921 aaaatacgaa agctgaacag aaagcccctg aacaaaaagc gcaggcagcg aagaaacacg
     1981 ccaagaaaca cagccatcag caaccggcaa aacctgctgc acaacccgca gcgtaagttt
     2041 tcaacagtaa tgctggcgcg ccccctcgcg cctgaaaatt acggtgctaa gcgggtaacg
     2101 tttagcaccg cctttagcgg agggtagtat ggtgggccgt tatcgctttg agttcattct
     2161 gatcatcctt attttatgcg cactgattgc cgcccgtttt tatctttcct gattgtagtt
     2221 atctgatttt actcccactt tcatcccgtc ccgtctatag tatttatgag ggtttgcttt
     2281 taataatcat aattacccac cagagtgtga tatgcgtaca accattgctg tagtgttggg
     2341 tgcaattagt ttgacgtctg cttttgtgtt tgcagataaa ccagacgttg ccagatcggc
     2401 aaacgatgag gtcagcaccc tgttttttgg tcatgatgat cgtgtgccag tgaatgacac
     2461 gacccaatca ccgtgggatg cggttgggca actggaaacg gccagcggca atttatgtac
     2521 ggcgacgctg attgcaccca atctggcatt aacggcagga cactgtttat tgacacctcc
     2581 aaagggtaaa gccgataaag cagtggcgct gcgttttgtg tcaaataaag gtctttggcg
     2641 ctatgagatc cacgacatag aaggccgcgt tgatccgaca ctgggaaagc ggttaaaagc
     2701 agatggggat ggttggattg tacctcccgc agccgcgccg tgggacttcg gattgattgt
     2761 gctacgtaat cccccttctg gcattacgcc gttgccgtta tttgagggag ataaagccgc
     2821 gcttaccgcc gcattaaaag cggcaggtcg taaagtgact caggcaggct accctgaaga
     2881 tcatctcgat acgttgtaca gtcatcaaaa ctgtgaagtg actggctggg cgcaaacgtc
     2941 ggtgatgtca catcagtgcg ataccttgcc gggtgacagc ggttcgcctc tgatgttgca
     3001 taccgatgac ggctggcaat taattggggt gcaaagttcg gctcctgccg cgaaagatcg
     3061 ctggcgcgcc gataaccggg ccatttctgt taccggtttt cgcgacaagc tggatcaact
     3121 gtcgcaaaaa taatgttcaa acgctgcccg acagcgcggg cagcgtcttc atcaggcaag
     3181 tttcaccatg atcattccag ccaacagcaa gaccaggcca atccagcctt tacgatttaa
     3241 ccgttgacca aacaagatcc aacctgcggc taacgtggcg gcaataccaa acccgcccca
     3301 caatgcataa gcgacagaca agtcgatccc tttaacggct tgagaaagcg cactaaaggc
     3361 agccagcacc gccgccaggg agagcaagcc aaatattttg cgacgaaagc cgtcagaaaa
     3421 tttcaaaaag acgttagcaa cgatttccag cacgattgcc aatgccagcc aggcggcgtg
     3481 aacccattca aactgcgcca tggttcacct ccagttcagg tttacgcgct ttacgggtac
     3541 ctgattttat caacacaatc ccggcgacca gggtggttaa cccggcaatt ttcatcagcg
     3601 ataaactttc gtcgaataac aaaacgctaa acaaggtaat aaataaaata ccgatacctt
     3661 cccacagcgc ataagctacg cctaaggcga tttttttaac ggcgaaagag agaaatatat
     3721 acgacagaga aatcatcacc agcattaaaa taaagccgcc atttccctca ctgacgctcg
     3781 cccatttcat tgacagcgta ccggtaattt ctgtagcaat agccagacct aataaaatcc
     3841 aataaatata cattgtcctt ctcctgcaag agaattattt taattttcgc ttaattcagc
     3901 gaaaccaaag taaagtggtc aagccccgcg catagcgcaa gctttggcag aagaaaggac
     3961 taaagcgcgt tgcgccagtg ctgctcacct acgagcaaga tagtggatga ggtacgaaga
     4021 tgggtaaatg tagaaaataa cgtcctgaac aaattgtcca taatattaca attatccgca
     4081 gtgttgcttc tcgtcatcgc ggatgataat tgtcctcggt agttgaacac gcctgatttg
     4141 tatcatagct taagaattaa ctcaaaatat tttcacttct ttacctgagc ggtttgattt
     4201 tcgttatgat gacggagcga aaaagacatt attattagca aaggaagaaa aaacggggac
     4261 aagcatggca aagccgatca tcacgctcaa tggcctaaaa atcgtcatta tgttgggaat
     4321 gctggtcatt attctctgcg gtatccgttt tgccgccgag atcatcgtgc cgtttattct
     4381 cgcattattt attgctgtta ttcttaaccc gctggtgcaa cacatggtcc gctggcgtgt
     4441 gccgcgtgta ctggcggtgt cgattttgat gaccatcatc gtgatggcga tggtgttgct
     4501 attagcttat ctgggttccg cgctcaacga gttgacgcgg acgttaccgc aatatcgcaa
     4561 ctctattatg acgccgctgc aagcgcttga accgttgttg caacgcgtag ggattgacgt
     4621 ctcagttgac cagctggcgc attatattga tccgaacgcg gcgatgacgt tgctcaccaa
     4681 cttattgacg cagttatcta atgccatgtc atcaatattt ttattgctgc tgacggtgct
     4741 gtttatgctg ctcgaagtgc cacaattgcc cggaaaattt cagcaaatga tggcgcgtcc
     4801 ggttgaaggg atggcggcga ttcaacgtgc gattgacagt gtttctcatt atctggtgct
     4861 gaaaacagcc atcagcatca tcaccggcct ggtcgcctgg gcgatgctcg ccgcactcga
     4921 tgttcgcttc gcttttgtct ggggattgct ggcctttgcg cttaattaca tcccgaatat
     4981 tggttcagtc ctcgcggcaa tcccccctat cgctcaggta ctggtgttta atggcttcta
     5041 cgaagcgttg ctggtgctgg cgggatatct gctgattaat ctggtcttcg gcaatattct
     5101 ggagccgcgt atcatggggc gtgggctggg gctttccaca ttggtggtat ttttgtcgtt
     5161 gattttttgg ggatggttgt taggaccggt gggtatgctg ctttccgtgc cgttgacaat
     5221 tattgtcaaa attgcgcttg aacaaacagc gggaggtcaa agcatcgccg ttctgttaag
     5281 cgatctcaat aaagagtgac ggcctcagca gaggccgtca gggttacaga gctttcagga
     5341 ttgcatccac gctggctttg gcgtcaccaa acagcatgtg ggtgttttcc ttgaagaaca
     5401 gcgggttttg cacaccagca tagccagtgt tcatcgaacg tttaaagaca atcacgttct
     5461 gcgctttcca cacttccagc acaggcatac cagcaatcgg actcttcgga tcatcctgcg
     5521 ccgccgggtt aaccgtatcg ttagcaccaa tcaccagtac ggtatcggta tcagcaaagt
     5581 catcattgat ctcgtccatt tccagcacga tgtcatacgg tacttttgct tcagccagca
     5641 atacgttcat atgtccaggc aaacgccccg cgaccgggtg gataccgaaa cgcacattaa
     5701 taccacgagc gcgcaatttc tcagtaattt cagcgacagg atattgcgcc tgcgcgactg
     5761 ccatgccgta ccccggagta atgatcactg aatgggagtt tttcagcagt tccgctgtct
     5821 cttctgcggt gatttcgcgg tgctcaccca cttcctgatc atcgccagta gaagagccgt
     5881 cggtgccgaa accacccgca ataacgctga taaaggaacg gttcattgcc ttacacataa
     5941 tgtaagaaag gatagccccc gaagaaccga ccagcgcacc ggtcacaatc agcaggtcgt
     6001 tgctgagcat aaagcccgca gccgcagccg cccagccgga gtacgagttc agcatcgaca
     6061 ccaccactgg catatctgca ccaccgatgg aggcgactaa atgccagccg aataccagcg
     6121 caattgcggt cattatcagc aatgccagca cttgcaggcc gacgctgtcc gtgcgaacaa
     6181 atacaatcag cagcaggaag gaaacgacca gagccgccag gttcattttg tgacggtttg
     6241 gcagcatcaa tggtttagac gaaatcttgc cacacagttt gccgaacgcc accaccgaac
     6301 ccgtgaacgt taccgccccg atgaagatac cgaggaacac ttccgtcagg tgaatattga
     6361 ccagaatcgg tgccattccc gcgtcatgat gcagatagct gttaaagcca accagcactg
     6421 ccgccagacc cacgaagcta tgcaggatcg ccaccagttc tggcatttcg gtcatttcaa
     6481 ctttcttcgc cagacggata ccaattgccc caccaatgac catcgccagc aagatccagc
     6541 caacattacc cgtatccggt ccaaaaatgg ttgcgattaa cgcaatcgcc atcccggcga
     6601 taccgaagtt gttaccctgg cgagacgttt catgtttcga aagaccggcc agactgaaga
     6661 taaacaggat cgcggcaaca atgtatgcag ctgtaactaa tcctccagac atatgttacc
     6721 ccttaatttt tgcggaacat ttttagcatg cgctgagtca cggtgaagcc accgaaaata
     6781 ttaatgctgg ctataagcac cgcgataaaa ctaaggaagc taacccagcc gccctggcca
     6841 atctgcaaca gtgctccgac aacaataatc cctgaaatcg cgttggtgac cgacatcaac
     6901 ggtgtatgca gcgcgtgcga tacattccac accacgtaat aaccgacaac gcaggccagc
     6961 gcgaaaacgg tgaagtgccc aaggaattct ttcggcgcaa cgcttgccat ccagccaaaa
     7021 agaatgattg ccagcgccat caacgcgtat ttacgccacg gtgagcaggt acatttttcc
     7081 tcagttttca cttccggtgc cgctttttgt gccgcctgcg gctgagctga tacctgaatc
     7141 ggcggtgccg gccaggtaat ttcgcccgca cggatcacgg tcacgccgcg aatcaccaca
     7201 tcatcaaaat caacagtgat attgccgtct ttctctttgc acaacagttt cagcagatta
     7261 acgaggtttg tgccgtaaag ctgtgaggat tgcgtcggca gacggcccgg aagatcggta
     7321 taaccaatca ctttgacacc attttccgta gtgaagattt cacccggcac ggtgtattca
     7381 cagttgccgc cgttttgggc tgccaggtcg acaatcacac tgcccgcctt catggagtca
     7441 accatttcac gggtaattag cttcggcgct ggtttgcctg gaataagcgc ggtggtgaca
     7501 atgatatcga cctcttttgc ctgggcggca aagagttcca tttccgcttt gatgaacgcg
     7561 tccgacatca ctttggcata gccatcgccg ctgccagctt cctctttaaa atccagctcg
     7621 aggaattccg cgcccatact ttgaacttgt tctttcactt ccgggcgggt gtcgaatgca
     7681 cgcacaatcg cgccgagact gtttgctgcg ccaatggcgg ccagacctgc aacacccgca
     7741 ccaatcacca tcacttttgc cggtggcact ttcccggccg cagtaatttg cccggtaaag
     7801 aagcgcccaa attcatgtgc cgcttcaaca atggcgcgat aaccggcgat gttcgccatc
     7861 gagcttagtg cgtccagcga ttgtgcgcgt gagatacgcg gcacagagtc catcgccatc
     7921 acggtcacgt tacgttccgc aagtttttgc attaattccg gattctgcgc aggccagata
     7981 aaactcacca gcgttgtccc aggattcagt aacgcaattt catcatctaa cggcgcattg
     8041 accttcagaa tgatctctga ctgccagacg ctattccctt ctacaatttc agcgcccgct
     8101 tgcacaaacg ctttatcgtc aaaacttgcc agttgacccg cgccgctctc taccgcgacg
     8161 gtaaaaccca gtttcagcag ctgttccact gtttttggcg ttgctgcaac acgggtttca
     8221 ttggttaacc gttctcttgg tatgccaatt cgcatgatat tcccttccat cggttttatt
     8281 gatgatggtt tgcctgtgtc aggagccaca caagctgctc atgtacgagc taaatgttac
     8341 tccgttaaaa taaattagta acaaacgccc tataacgtac tgaaaattat gcctgtgatc
     8401 tagcgccaaa aatcagtatt tcggcgtgaa ctcgcaaaat attaacgatt cagccgtgat
     8461 agtgggataa acaccttaga acgccggata aagactgata attgtcttcg acggtcgggt
     8521 aaaacgagac atcgccccgg cacgaatcac tacttaacat taaattaact tatacaattc
     8581 agttgcttca gtagtaatga tgctgatacg gctgtttttt aagcatagac ggtcatttga
     8641 gcaggattaa aattggctta aggaatgtga tatgaaaaat gacgcagaca gttacaccgt
     8701 ttaaatgcaa taatcagcca cgtttctcgt taataacaat accagtacct ggtttgcgca
     8761 aggcgaagga ttatttttat gaagcttaag aacaccctcc tggcgtcggc actgctttct
     8821 gctacggcat tctccgttaa cgcagcaaca gaactgacac cggagcaagc ggcagcggtt
     8881 aaaccttttg accgtgtagt ggttaccggt cgttttaatg ctattggcga agcggtgaaa
     8941 gccgtttctc gtcgcgcaga taaagaaggt gccgcctctt tttatgttgt cgacacttct
     9001 gattttggta acagcggtaa ctggcgtgtg gtcgctgacc tctataaagc cgatgctgaa
     9061 aaagcagaag aaacaagtaa tcgcgtaatt aacggtgttg tcgaactgcc gaaagatcag
     9121 gctgttctga ttgaaccgtt tgacacggtc accgtccagg gcttctatcg tagccagcca
     9181 gaagtcaatg atgccatcac caaagcggca aaagcgaaag gtgcctactc tttctacatc
     9241 gttcgtcaaa tcgatgccaa ccagggcggc aaccagcgta ttactgcatt catctataaa
     9301 aaagatgcta agaaacgtat cgtccagagc ccggatgtga tcccggcaga ttccgaagca
     9361 ggacgtgcag ctctggctgc tggtggcgaa gccgcgaaga aagttgagat cccgggtgtt
     9421 gcgactaccg catcaccaag ttctgaagtc ggtcgcttct ttgaaaccca gtcatcaaaa
     9481 ggcgggcgtt acaccgtcac gctcccggat ggcactaaag tcgaagaact gaacaaagcg
     9541 accgcagcga tgatggtccc gttcgacagc atcaaattct ctggcaacta cggcaacatg
     9601 accgaagtct cctatcaggt tgcgaaacgt gccgcgaaga aaggtgctaa gtattaccac
     9661 atcacccgcc agtggcagga acgtggtaat aacctgaccg tcagcgcaga tctgtataaa
     9721 taactattca gttactccta taaggcggct tgatgccgcc tttcgcattt ttagtcacaa
     9781 atttccccgc gaccattgca tgcagacaca tctcttcgta aaatcccgcg cttcagtggc
     9841 aaactccatt tttatgcgtt ttgccctaat atttattctt cttatcacgt tttaatcact
     9901 ggatatcgat ggaaaagaaa ctgggactga gcgcactcac cgcgctggta ttaagctcaa
     9961 tgctgggcgc gggtgttttc agtctgccgc aaaatatggc ggcagttgcc agcccggcag
    10021 cactgctcat cggctggggt attactggcg ctggcatttt attgctggcc tttgccatgc
    10081 tgatcctcac gcgcattcgt cccgaacttg acggcggtat ctttacctat gcccgcgaag
    10141 ggtttggcga gctaatcggc ttttgttccg catggggata ctggctgtgc gcagtcatcg
    10201 ccaacgtctc ctatctggtg atcgtttttt ccgcgttaag cttttttacg gacacgccgg
    10261 aattgcgcct gtttggcgat ggtaatacct ggcaatcgat agtcggtgca tcggctttat
    10321 tgtggattgt tcactttttg atcctgcgcg gggtgcaaac cgctgccagc attaacctgg
    10381 tggcgacact ggcaaaattg ttgccgctgg gtctgtttgt tgtgctggcg atgatgatgt
    10441 tcaaactgga taccttcaag ctcgacttca ccggacttgc acttggcgta cccgtttggg
    10501 aacaggtgaa aaacaccatg ctgatcaccc tgtgggtttt cattggtgtg gaaggtgccg
    10561 tggttgtttc tgcgcgtgcg cgtaataaac gtgatgttgg caaagcgaca ctgctggcgg
    10621 ttctctccgc tctgggcgtt tacttgctgg taacgctgct ttcgctgggt gtggtggcac
    10681 gtcctgaact ggctgaaatt cgtaacccgt caatggccgg tctgatggtg gaaatgatgg
    10741 gaccatgggg cgaaatcatc atcgctgccg gtttgatcgt ttccgtttgc ggcgcgtact
    10801 taagctggac catcatggca gcagaagtac cgttcctggc cgccactcat aaagcattcc
    10861 cgcgcatttt tgcgcgccag aacgcacaag ctgcgccatc cgcctcactg tggttgacca
    10921 acatctgcgt gcaaatttgt ctggaactca tctggctgac cggttccgat tacaacacgt
    10981 tgctgaccat cgcctcagaa atgattctgg tgccctattt cctggtcggc gcgttcttgc
    11041 tgaaaatcgc aacccgtcca ctgcataaag cggtaggtgt cggtgcctgc atttatggct
    11101 tatggttatt gtacgcctct ggtccaatgc acttgctgtt atccgttgtt ctgtatgcac
    11161 cggggctgct ggttttcctg tacgcgcgca aaacgcatac ccatgataat gtactgaacc
    11221 gtcaggaaat ggtgctgatt ggcatgctgt taattgcctc agttccggcg acctggatgc
    11281 tggtgggata acgttcatcc catcgttgga tagcaaagga gataacgatg ggtaaaaccc
    11341 agcccttgcc aatattaatt actggcggag gtcgtcgcat cggcctcgcc ctcgcatggc
    11401 atttcattaa tcaaaagcaa ccggtgattg tcagctatcg gacacactat ccagccattg
    11461 atggactgat taatgcaggt gcgcagtgta ttcaggctga tttttcgacc aacgacggtg
    11521 tgatggcgtt tgccgatgaa gtactaaaaa gcacccatgg tctgcgtgct attttgcata
    11581 acgccagtgc gtggatggcg gaaaaaccgg gtgcgccact ggccgacgta ctggcttgca
    11641 tgatgcagat ccacgttaat accccatacc tgctcaacca tgcgctggaa agattactgc
    11701 gtgggcacgg acacgccgcc agcgatatca ttcactttac cgattatgtg gtggagcgcg
    11761 gtagcgacaa acatattgcg tatgctgcaa gcaaagcggc actggataat atgacccgct
    11821 cgtttgcccg caagctggca ccggaagtga aagtgaattc tattgcgcca tcgctgatcc
    11881 tgtttaatga acatgatgat gccgaatatc gacaacaggc gctgaataaa tcactgatga
    11941 aaaccgcgcc tggcgagaaa gaagtgatcg acctggtcga ttacttactt accagttgct
    12001 ttgtcaccgg acgcagtttc ccacttgatg gcggtcgtca tctgcgttaa tgcagcttta
    12061 tccagcatat aatcaacacc catgcgctta tcccccaaca cgcaacagaa ccaacaaaag
    12121 cggcgggcaa gcgcatcatt ccggtgaaat accacagcga caccaggtaa acaaaatagg
    12181 gaataatcga ccacatacta aaaatgatgg ttgcgcgtaa ggcttcaatg ccgcgttcgc
    12241 tggcaacaat ataatgcgcg ataagcgcaa aggtcgggaa aagtggaatc agcccggcga
    12301 tataataatt tttcgttttt gctaaaacac caatcaacag cactaccagc gcaccgagcg
    12361 cggctttgat taccagcccc atctttttac cttaacactt ccataacaag tcatcagtag
    12421 aatacctgat gaaaacttgt ttagaaacga ttgatagtaa gtaaaaacag cgcggtgtat
    12481 tgtgacgttt ttatatctac cgtgaatgtt atgaacacta tcgtatttgt ggaagatgat
    12541 gcggaagtcg gttcactgat tgccgcgtac ctggcaaaac atgatatgca ggttaccgta
    12601 gagccgcgcg gcgaccaggc cgaagaaacc attttgcgag aaaatccgga tttggtgtta
    12661 ctcgacatca tgctaccagg caaggacggc atgaccattt gtcgtgattt acgcgcaaag
    12721 tggtctggac cgattgttct tctaacctct ctcgatagcg atatgaacca catcctggca
    12781 ctggaaatgg gtgcctgcga ctatattctc aaaacgacgc cccctgctgt tttgctagcg
    12841 cgtttacgtt tgcatttgcg tcagaatgag caagccacac tgaccaaagg tcttcaggaa
    12901 acgtctctga ctccctacaa agccctgcat ttcggcacgt tgaccatcga tcccatcaac
    12961 cgcgtagtca ccctggctaa cactgaaatc tcgctctcga cagctgattt cgaattattg
    13021 tgggaattag ctacccatgc cgggcaaatc atggaccgcg atgcattgct gaaaaattta
    13081 cgcggcgtca gttatgacgg actggatcgt agcgtggacg tggctatttc gcggttaaga
    13141 aaaaaactgc tcgataacgc cgcagaacct tatcgcatta aaactgtgcg taacaaaggc
    13201 tatctttttg cgcctcatgc atgggaataa gcgatgaaaa aactgtttat ccagttttac
    13261 ctgttattgt ttgtctgctt ccttgtgatg tctctgctgg ttgggctggt gtacaaattt
    13321 accgccgaac gcgcgggcaa acagtcgctg gatgatttga tgaacagttc gctgtatctg
    13381 atgcgcagcg aattgcgtga gatcccccca cacgactggg gtaaaactct gaaagagatg
    13441 gatttaaatc tctctttcga tctgcgtgtc gagccactga gtaaatacca tcttgatgat
    13501 atttccatgc accgactgcg tggcggcgaa attgtcgccc tggacgatca gtacacgttt
    13561 ttgcagcgta tcccgcgcag ccactacgtg ctggcagttg gtcctgttcc ttatctttat
    13621 tatctccatc agatgcgatt gctggatatc gccctgatcg cttttattgc tatttccctc
    13681 gcctttccgg tgtttatctg gatgcgtccg cactggcagg atatgttaaa actggaagca
    13741 gcggcgcaac gatttggcga tgggcatctc aatgaacgta tccactttga tgagggttcg
    13801 agctttgaac gacttggcgt cgcatttaac cagatggcgg acaatatcaa cgccttaatt
    13861 gccagcaaaa aacagcttat tgacggtatc gctcacgaac tgcgaacacc gttagtgcgc
    13921 ctgcgttatc gactggagat gagcgataac ctgagcgccg ccgaatccca ggcgttgaat
    13981 cgtgatatca gtcaacttga agctttaatt gaagagctgc tgacttatgc ccgactcgat
    14041 cgcccacaaa acgagcttca tcttagcgaa ccagacctgc cgttgtggct gtcaacgcat
    14101 ctggcagata ttcaggcagt aacgcccgat aaaacggtac ggataaaaac gctcgtgcaa
    14161 ggccattatg cggcgttgga tatgcgctta atggagcgcg tgctggataa tttgctcaat
    14221 aacgccctgc ggtactgcca ttcaacggtt gaaaccagcc tgctactgtc ggggaataga
    14281 gcgacattaa ttgttgagga tgatggccca gggattgccc cagaaaaccg cgaacatatc
    14341 tttgaacctt ttgttcgcct cgatcccagc cgggatcgct caaccggcgg ctgcgggctg
    14401 gggctggcaa ttgtccactc tatagcactg gcaatgggcg gtacggttaa ttgtgacacc
    14461 agcgaactgg gtggtgcccg cttctcgttt agctggccgt tatggcataa catcccgcaa
    14521 tttacctctg cctgacacta cgcgcacgat ggtcaagtca ccacgactgt gctataaaat
    14581 aagtatgttg taactaaagt ggttaatatt atggcgcgtt acgatctcgt agaccgactc
    14641 aacactacct ttcgccagat ggaacaagag ctggctatat ttgccgctca tcttgagcaa
    14701 cacaagctat tggttgcccg cgtgttctct ttgccggagg taaaaaaaga ggatgagcat
    14761 aatccgctta atcgtattga ggtaaaacaa catctcggca acgacgcgca gtcgctggcg
    14821 ttgcgtcatt tccgccattt atttattcaa caacagtccg aaaatcgcag cagcaaggcc
    14881 gctgtccgtc tgcctggcgt gttgtgttac caggtcgata acctttcgca agcagcgttg
    14941 gtcagtcata ttcagcacat caataaactc aagaccacgt tcgagcatat cgtcacggtt
    15001 gaatcagaac tccccaccgc ggcacgtttt gaatgggtgc atcgtcattt gccggggctg
    15061 atcaccctta atgcttaccg cacgctcacc gttctgcacg accccgccac tttacgcttt
    15121 ggttgggcta ataaacatat cattaagaat ttacatcgtg atgaagtcct ggcacagctg
    15181 gaaaaaagcc tgaaatcacc acgcagtgtc gcaccgtgga cgcgcgagga gtggcaaaga
    15241 aaactggagc gagagtatca ggatatcgct gccctgccac agaacgcgaa gttaaaaatc
    15301 aaacgtccgg tgaaggtgca gccgattgcc cgcgtctggt acaaaggaga tcaaaaacaa
    15361 gtccaacacg cctgccctac accactgatt gcactgatta atcgggataa tggcgcgggc
    15421 gtgccggacg ttggtgagtt gttaaattac gatgccgaca atgtgcagca ccgttataaa
    15481 cctcaggcgc agccgcttcg tttgatcatt ccacggctgc acctgtatgt tgcagattaa
    15541 cgcccggctt tcatactgcc gaccatctgt tctggccgta cccagctgtc aaactcggct
    15601 tcgctaagat accccagcgc aagggccgca gcttttaagg tcagcccttc tttatgcgct
    15661 tttttggcga tctcggcggc tttgtcataa ccaatgtggg tgttaagcgc agtcaccagc
    15721 atcagcgatt cattgagtaa ttgattgatt cgctcacgat tcggttcaat acccactgcg
    15781 cagtgtttgt taaaactttc catgccatct gccagcaagc gcaccgattg caggaaattg
    15841 tggatcacca ttggacggaa gacgttcagt tcaaagttac cggaagcgcc ccccatgttg
    15901 atcgccacgt cgttccccat cacctgacag cagagcatgg ttaatgcctc acactgtgtt
    15961 gggttcactt tccccggcat gattgagctg cccggctcat tttccgggat tgagatttca
    16021 ccaattccgc agcgcgggcc agaggccagc cagcggacat cattggcgat tttcatcagt
    16081 gacgcagcca accctttcaa cgcgccgtgc gcctgaacca gggcatcaca ggtcgccagc
    16141 gcttcaaatt tgttcggcgc ggtaacaaac ggtgcacagg taatgactgc cagttcatct
    16201 gctacgcgac gcgcatactc cggatgggta tttagtccag tacccaccgc tgtaccgcca
    16261 agagccagtt ccgctacgtg aggcaggctg tattcgatat gtttgagatt atgctcgagc
    16321 atcgctaccc agccggaaat ctcctgcccc agcgttaacg gcgtggcatc ctgcaagtga
    16381 gtacgaccaa ttttgacgat atcggcaaaa gcacgggatt tctcattcag tgtctgtgtc
    16441 agggttttaa gctgaggaat gagttgcttg cgcagcgcca gcagcgccgc aacgtgcatc
    16501 gccgtcggaa agacatcgtt ggaactttgg cttttgttca cgtcgtcgtt agggtgaact
    16561 ttacgttcca tcccgcgcac accgccgagt aattcactgg cccggttagc cagcacttcg
    16621 ttcatgttca tgttactttg cgtgccggag ccggtctgcc agatagccag cgggaattcg
    16681 tcgtcatgct gtcctgccag tacttcatcc gccgcctgac gaatggcgct cgctttctct
    16741 tcagacaaca agcctaaatc ttcattaact tttgccgctg cacgcttggt tagcgccagc
    16801 gcatgaatca gtgaggtggg cattttctcc gtcgaaatgc ggaaatgctc cagcgagcgt
    16861 tgagtttgtg cgccccacag cttatctgcc gggacatcaa tcgcccccat cgaatctttt
    16921 tcgctgcgta ctgtattcat gacctgctcc tcacctgatt aattttttct ttctgttttg
    16981 ctttcgttaa gcaactttta gctcacttat tatttaccat ttgataacaa atgtttggtc
    17041 tttcgtgcca tgtaaaaaaa ccgccccgaa gggcggctct gtttatttca cacagcgggt
    17101 gcattgtgtg agttgtatct gctggaagaa gtcatttcct ttatcatcca caaggataaa
    17161 cgccgggaaa tcttccactt caattttcca gatggcttcc attcccagtt ccggatattc
    17221 aacacattcc aggctcttaa tacttccctg cgccaataca gcggccggac caccgatact
    17281 gccaaggtag aagccgccgt gttttttaca ggcatccgtc acctgctggc tgcggttgcc
    17341 tttcgccagc atgatcatac ttccgccctg cgcttgcagt tgatcgacat aagaatccat
    17401 ccgtccggcg gtcgttgggc caagagaacc ggaggcataa ccttccggcg ttttggccgg
    17461 acccgcgtag taaatcggat gatctttgat gtactgcggc agcccttcac cgttatccat
    17521 ccgctctttc agtttggcgt gagcaatatc acgaccgacg ataatcgtgc cgttaagcga
    17581 taagcgtgta gaaacgggat actgcgacaa ctgtgcgagg atctctttca tcggacggtt
    17641 aaggtcaacg cgcaccgctt cgccttctcc cgctttgcgc agctcttccg ggatatattt
    17701 gcctggatta tgttccagtt tttcgatcca gatcccctga cggttgatct tcgctttgat
    17761 attacggtca gcagagcagg agacgcccat accgaccggg caggatgcgc cgtgacgtgg
    17821 caggcgaatc acgcggatgt cgtgagcgaa gtatttacca ccaaactgcg cacccagacc
    17881 aagattttgc gcttcgatca gcaattcttt ttccagttcc acatcgcgga acgcctgacc
    17941 gtgctcattc ccttccgttg gcagttcatc atagtatttc gcggaagcca gtttcaccgt
    18001 tttaaggttc gtttctgcag aagttccacc aataacgaac gcaatatgat acggaggaca
    18061 ggccgccgta cccagcgtgc gcatcttctc aaccaggtaa tttttcagtt tccccggcgt
    18121 cagtaacgct ttggtttcct gatagagata cgtcttgttt gccgaaccac cacctttggc
    18181 gatacagagg aatttgtatt cgtcgccatc aacggcataa agatcgatct gcgctggcag
    18241 attggtgccg gtattcactt ctttatacat atccagcggc gcgttttgcg agtagcgcag
    18301 attatcttcg atataagtgt tatagacacc gcgcgccagc gccgcttcat caccaccacc
    18361 ggtccataca cgctgccctt ttttaccaac aataatcgcg gtgccggtat cctgacaggt
    18421 tggcagaacg cctttcgccg cgatgtcgga gttacgcagg aattgcagcg ccacatattt
    18481 atcattttcg ctggcctccg ggtcacgcag aatgtcggcc acctgttgtt ggtgcgccgg
    18541 acgcagcatg aacgacgcat catgaaacgc ctggcgcgcc aacagagtta acgcttcggg
    18601 tgcgactttc aaaatctcct gcccttcaaa ttcagatacg ctaacgtgtt cgctggttag
    18661 caggtaatac tcagtatcat cttttttgag tggaaaagga gcctgataat gaaagggttt
    18721 gtttgacatt gttctctcac ttactgcctg gtttggttat gctctgggcg ggtgttccgt
    18781 tgccctgtta aaagcgagta acaatatcct acacactttt ttaacaaaaa ctgagactag
    18841 tacgactttt tgcggctcca ggttacttcc cgtaggattc ttgctttaat agtgggatta
    18901 atttccacat taaaacaggg attgatcatg caaaaactca ttaactcagt gcaaaactat
    18961 gcctggggca gcaaaacggc gttgactgaa ctttatggta tggaaaatcc gtccagccag
    19021 ccgatggccg agctgtggat gggcgcacat ccgaaaagca gttcacgagt gcagaatgcc
    19081 gccggagata tcgtttcact gcgtgatgtg attgagagtg ataaatcgac tctgctcgga
    19141 gaggccgttg ccaaacgctt tggcgaactg cctttcctgt tcaaagtatt atgcgcagca
    19201 cagccactct ccattcaggt tcatccaaac aaacacaatt ctgaaatcgg ttttgccaaa
    19261 gaaaatgccg caggtatccc gatggatgcc gccgagcgta actataaaga tcctaaccac
    19321 aagccggagc tggtttttgc gctgacgcct ttccttgcga tgaacgcgtt tcgtgaattt
    19381 tccgagattg tctccctact ccagccggtc gcaggtgcac atccggcgat tgctcacttt
    19441 ttacaacagc ctgatgccga acgtttaagc gaactgttcg ccagcctgtt gaatatgcag
    19501 ggtgaagaaa aatcccgcgc gctggcgatt ttaaaatcgg ccctcgatag ccagcagggt
    19561 gaaccgtggc aaacgattcg tttaatttct gaattttacc cggaagacag cggtctgttc
    19621 tccccgctat tgctgaatgt ggtgaaattg aaccctggcg aagcgatgtt cctgttcgct
    19681 gaaacaccgc acgcttacct gcaaggcgtg gcgctggaag tgatggcaaa ctccgataac
    19741 gtgctgcgtg cgggtctgac gcctaaatac attgatattc cggaactggt tgccaatgtg
    19801 aaattcgaag ccaaaccggc taaccagttg ttgacccagc cggtgaaaca aggtgcagaa
    19861 ctggacttcc cgattccagt ggatgatttt gccttctcgc tgcatgacct tagtgataaa
    19921 gaaaccacca ttagccagca gagtgccgcc attttgttct gcgtcgaagg cgatgcaacg
    19981 ttgtggaaag gttctcagca gttacagctt aaaccgggtg aatcagcgtt tattgccgcc
    20041 aacgaatcac cggtgactgt caaaggccac ggccgtttag cgcgtgttta caacaagctg
    20101 taagagctta ctgaaaaaat taacatctct tgctaagctt attaaaggct tataacacct
    20161 tcaggcggcc agtccgcctg atttcatttt atggataatc attatgaata aatcgctggt
    20221 agcggtaggc gtcattgttg cgctaggcgt agtctggaca ggcggcgcat ggtatacagg
    20281 caagaagatt gaaacccatc tcgaagacat ggtcgcgcag gcgaacgcgc aactcaaact
    20341 gacagctcct gaatccaacc tggaagtgag ttatcaaaac tatcatcgcg gcgtattcag
    20401 cagccagttg caactgttgg tgaaacccat tgccgggaaa gaaaatccgt ggattaaaag
    20461 cggtcagagc gtcatcttca acgaatcggt tgatcatggt cccttcccgc ttgcccagct
    20521 taaaaaactg aacctgatcc cgtcgatggc atcaattcaa accacgctgg ttaataacga
    20581 agtaagcaaa ccactgtttg atatggcaaa aggtgaaacg ccttttgaga ttaactcgcg
    20641 cattggttac agcggtgatt ccagttccga tatttcgctc aagccactga attacgagca
    20701 aaaggatgaa aaagtcgcct ttagcggcgg cgagttccag ttaaatgctg acagagacgg
    20761 caaagccatc tccctttccg gggaggcgca aagtggtcgg atagacgcag ttaacgaata
    20821 caaccagaaa gtgcagttga cctttaataa tctgaaaacc gacggttcca gcacgctggc
    20881 aagttttggt gagcgtgtag gaaatcaaaa actgtcactg gaaaaaatga ccatttcagt
    20941 ggaaggcaaa gaactggcac tgctggaagg catggagatc agcggtaaat cggatctggt
    21001 caatgacggt aaaacgatca atagccaact ggattactcg ctaaacagcc tgaaggtaca
    21061 gaatcaggat ctgggcagcg gcaagctgac tttaaaagtc ggccagattg atggtgaagc
    21121 ctggcatcag tttagccagc aatataacgc gcaaactcag gcgctgctgg cacagccaga
    21181 aattgccaac aaccccgaac tttatcagga gaaagtgacg gaagccttct ttagcgccct
    21241 gccgctgatg ctgaaaggcg atccggtgat tactatcgcg ccgctaagct ggaaaaacag
    21301 tcagggtgaa agtgccctga atctgtcgct gttcctgaaa gatccggcaa cgactaaaga
    21361 agcgccgcaa acgctggcgc aggaagtaga tcgttcggtt aaatctctgg atgcgaaact
    21421 gaccattccg gtggatatgg caactgagtt tatgactcag gtagcgaagc tggaaggtta
    21481 tcaggaagat caagcgaaaa aactggcgaa acagcaagtt gaaggtgcat cagcaatggg
    21541 gcagatgttc cgtctgacca ccttgcagga caataccatc accaccagcc tgcaatatgc
    21601 taacggtcag ataacgttaa atgggcagaa aatgtcgtta gaagattttg ttggcatgtt
    21661 tgcgatgcca gctcttaacg ttccggctgt accggcaatt ccgcagcagt aattcacggc
    21721 caaaacgccg gagaattttc actccggcgt tttcatctga aaacaaacca gagattgcct
    21781 gatgcgctac gcttatcagg cctacctttt cctgcaacac tttgaattta tgagtttttg
    21841 taggctggat aaggcgttta cgccgcatcc ggcataaaaa acgcgcactt tgtcaacaat
    21901 ctgaaacgcc ggagattttt ctctccggcg ttatttttta cttcagcata aagtcatact
    21961 gaatactcat tttcacatcc cagtaattca ggcgatcgcc cagcgtactg ccatcgcgct
    22021 tttcccgccc tttatcggca gcaagaaaga aattcatccc ttgtaacggc ccttcgctga
    22081 cccgatagtt cataccacct aagatacccg tgccttcaat ccgcacatct cgtttactgg
    22141 attcatagcc gcgagtcaca atcggtgcaa atgtcagcgt aaattgcggc gttaaacgat
    22201 agttgacgcc caattgccag gactgcattc cttcacggtt acgatcaaga cttaatgaaa
    22261 agggatagcc aatgtcggta tccaccacgg caccattcat tgcatggcgc aaataaccac
    22321 cactgccaaa tacacttccc cacggcgcat tccaggtcaa ttgtccacta accaacgccg
    22381 tttcattggg ctggctggta ttacgactta aaccttcgag ctgcgcgtaa aagccgagca
    22441 actccccttt caacgtataa ttcgggtcga gcggtatgct tttctcgaga atactttgta
    22501 tctgattgga aacatctttc tgtaccgatg cccccagaga atagcgactg gtatcatcat
    22561 gccaactggc ggctaaaaaa gaacgtgcgc gatgtttatc gtattttccc gtctggctgt
    22621 tatacacccc ttcatcacga ataccggttg ttgaatcagt ccataaaaat actcgtgaac
    22681 gccacattcc ccacagatca atatttggtg ttaaagccca ataacctaat gctccttcag
    22741 aaactgtcgg taatgtacgt tgcgaactgc cagccattaa cggaatacga taaggtaagc
    22801 taccataact ataatccgtc ccgaagcgac ctaatttaag caggctattt tcactgggtt
    22861 ttatttttac tgcccccagg gcaaagccaa aacttttatc accatcaaga taccaccggg
    22921 tactcatatc agcacgagca cctaatttat aaacataata cgccccgcct tcaacgccaa
    22981 taatattgga ataataacca ctattgaaat cgagcaatcc tccctgtacc catgcgtaaa
    23041 tatctcttcc cgcgccagca ctgggcttat ccgccctgcg caattcgttt ttcagtctga
    23101 tgcgtagtcc cgcttcatcg tcagccagtt gcgccgcata agcagaggta aggccagagg
    23161 cagccgtcag gcaaataacg gccatggcca ctatttttct catagttgca cctttgatgt
    23221 tctgattatt tttattgaat attaattagt gatatcgctg attaattgct gctgcacttt
    23281 tttacgatta tcaatttcaa ccacgatttc tttgaatttt ttatccgtga gcggataaaa
    23341 ccagataata acgaatgcca gtagcataaa tccgcaaggt actaaggcaa ttgatgtgcg
    23401 gatgcccata ataacttccg gcgtttgcac ctgattggcg atatatccgc ttaaccccaa
    23461 aataaaggca ggaattgaac ctccgattgc ctgaccgcat ttacgggtaa atgagaatag
    23521 tgaataggtg agcccttcaa ttcgcacgcc ggtcaggtat tcaccgtatt ctacggtatc
    23581 agcttccagc gcccacatca cggtcatggt aacgccctga ccaattgaag cgatggccaa
    23641 cgcaaccaac gccaccggca gtgaccagac ggaaacccag aagaacagca gataaccgca
    23701 ggttcccagc aaagcgccaa tcaggaaggt attcttttta ccgatcctcg cgaccatccc
    23761 cggcaccagc ggtgccgatg ccacagtacc aaccaggttt tgcaccagta ccagcacagt
    23821 gaacagcccg gtatcattta acacatagcg cacgtagaac aacgacgagg cgctgaccgc
    23881 aaaggtcgaa atcagcacac acagcgcacc gatgcacaac ataaacagcg ggcgattccg
    23941 tttcagggtt tgcagactga tattcaatga cggctgcgca acgatacgta ccacattctc
    24001 acgcgtcgat ttgaagcaga tgaagtaaag caccattccg gcaatcgcca gcacaattgt
    24061 ccagaaatgg tataccgaca ccatctcttc cgggctggag ttcttaatgc tcggtcctat
    24121 cagaaatgcc aggcagacaa aggtcaatga agcggcaatc ccacgagccg cgcccagacg
    24181 ggcgcgggat tgtggttgtt gggtcatcgc ggtagcaagt gaaccataag gaatattcac
    24241 caggctgtag caaagcccga ggcccatgta ggtcaaatat gcatacacca ctttgctacc
    24301 atggctccag tcggtcggca cccagaatac cagcacgctg aagatcatta acggcgcagt
    24361 accgaagagt aaaaacgggc ggaattttcc ccagcgggta ttcacactgt ccaccactcg
    24421 tccggcaaag acgtcggcga aggcatcgaa tacccgcacc agtaacagca tggtgcccgc
    24481 cgcagcggca ccgacgccag cgacgtcggt gtagtaactc aacaggaaga gcgcccccat
    24541 tgcgaaggcg aagttattgg cgacgtcacc gaggctgtag ccgacgatgg tgcgccagga
    24601 gagttgttga ttcattgttt gcctccctgc tgcggttttt caccgaagtt catgccagtc
    24661 cagcgttttt gcagcagaaa agccgccgac ttcggtttgc ggtcgcgagt gaagatccct
    24721 ttcttgttac cgccaacgcg caatatgcct tgcgaggtcg caaaatcggc gaaattccat
    24781 acctgttcac cgacgacggc gctgacgcga tcaaagacgc ggtgatacat atccagccat
    24841 gcacactgat actcttcact ccacatgtcg gtgtacattg agtgcagccc ggctaacgta
    24901 tccacgccgt attcggtgat gataatcggc tgatgcagtt tctcctgcca ggccagaagt
    24961 tctttttcca gtaccttctc tgccgtttcc aaatcgccgc tttggacata ccatccgtaa
    25021 taacggttca ggcacagcac atcaaagaga tcgctgatgg tatcggtgtg agcgtcgcag
    25081 aacattacat tgacgcaggt gatcggacgc gtcgggtcga gtttacgcgt tgcttccgcc
    25141 agtggcgcga aatattcccg tgcaccttgc ggacgggtat ccggttcgtt ggcaatactc
    25201 cacatcacca cgcttgggtg gtttttgtca cgcgctatca gctctttaat cgcctgtaag
    25261 tgcgcttgct gagtttcccc gttgactgcc tcttcgctgt acagttcttt cggcttgttg
    25321 cccgcttcga aaccaatgcc taaagagagg ttaaagccga cagcagcagt ttcatcaatc
    25381 accacgatgc catgttcatc tgcccagtcg agcatctctt cagcgtaagg gtaatgcgag
    25441 gtacggtagg agttggcccc aatccagtcc attaatgcgt ggtcgtgcac catcagcacg
    25501 ttatcgaatc ctttgccacg caagtccgca tcttcatgac gaccaaagcc agtaaagtag
    25561 aacggtttgt ggttaatcag gaactgttcg cccttcactg ccactgaccg gatgccgacg
    25621 cgaagcgggt agatatcaca ctctgtctgg cttttggctg tgacgcacag ttcatagaga
    25681 taaccttcac ccggttgcca gaggtgcgga ttcaccactt gcaaagtccc gctagtgcct
    25741 tgtccagttg caaccacctg ttgatccgca tcacgcagtt caacgctgac atcaccattg
    25801 gccaccacct gccagtcaac agacgcgtgg ttacagtctt gcgcgacatg cgtcaccacg
    25861 gtgatatcgt ccacccaggt gttcggcgtg gtgtagagca ttacgctgcg atggatcccg
    25921 gcatagttaa agaaatcatg gaagtaagac tgctttttct tgccgttttc gtcggtaatc
    25981 accattcccg gcgggatagt ctgccagttc agttcgttgt tcacacaaac ggtgatacgt
    26041 acacttttcc cggcaataac atacggcgtg acatcggctt caaatggcgt atagccgccc
    26101 tgatgctcca tcacttcctg attattgacc cacactttgc cgtaatgagt gaccgcatcg
    26161 aaacgcagca cgatacgctg gcctgcccaa cctttcggta taaagacttc gcgctgatat
    26221 cagacgttgc ccgcataatt acgaatatct gcatcggcga actgatcgtt aaaactgcct
    26281 ggcacagcaa ttgcccggct ttcttgtaac gcgctttccc accaacactg atcaattcca
    26341 cagttttcgc gatccagact gaatgcccac aggccgtcga gttttttgat ttcacgggtt
    26401 ggggtttcta caggacgtaa cataagggac tcctcattaa gataataata ctggtcaacc
    26461 tttaatctga ttagttaacc aattctgtgt tgcacacagt tatctgtgag aaacccatgg
    26521 aagagaaatg gaaataaaaa gaactgacac cgcgatcaaa aaaccaaaaa ctgcaatacc
    26581 cacagcgtga tatagatcgc attaatcttt aaaacagcgt tgacagaagc cataaaataa
    26641 gcaaccgaac gttcgttcga gcgtattggg aacgataaac tctcatgaca tatggctaca
    26701 gtgaatattt tggggggaat tctccgaagc cgggaaggat aatttttgca cagagaaatt
    26761 acgatatgaa acgcgggcac agttatcacc agcccgccga aaaagagaga gaatcaggat
    26821 gcggttaaga taccgccaat catcgcgcgt aatccctgag caaacgacgc ttcacgcgcc
    26881 aggtcttccg cttcgatatc ggccagtaca ccgtaggtca gatccagcag taaacgtgaa
    26941 gtcattgccg tgttgatgtc tgggcttatc tcgccttttt gctgggcatc acgcatccgc
    27001 tgggcaacaa attccgtgat cgtcatatgc ttatttttaa gcatggcggc gacctgtggg
    27061 ttacgcatcc cttccgccat aatttcaacc accagcgccc gttgtccaaa ggcttcatgg
    27121 gtgagagaga caatggactc gaccatatag tcaacgaaat gaatcccttc aatcggttcc
    27181 cggaaacggg ccagcgccct ctcctggtcc tgtaagataa tcgcctgaat caaggcttct
    27241 ttggagatga aatggtgata gagcgtcccg ggactaatgg cgcaagattt acagatggct
    27301 ttcatcgagg cactgtgaaa tccattttct gaaaaaatct ctctggcagc attgaggatc
    27361 cgggtccgtg tcggttgtgc ttcagtctgc atgttatcca tcattaaacc attatagtta
    27421 gcgtgaataa ctagtttacc gcgttgtcag gtgagcgcct atcattgctg ttgaatagtg
    27481 cgaaggcaca ctctattcgt atacttttca ctctgaaatt ggttaaccaa tagccgtgat
    27541 ttggctgcca gttatttagc agagacgttg atgagtttat cccggtaaac aacacgcacg
    27601 gttgtttacc ggtccgttag tgtattaatt gagctcctgt accccaccac cggagacggt
    27661 gagaatttgt ccgcttaccc agctcgcagc aggcgagcaa aggaacagcg ctgcgttagc
    27721 aatatcttgc ggttggccca gacgtctgat cggcgtgtgc tgtaacattt tttgttcaat
    27781 ttctggtgta ataacggatt tcagggcatc ggttaatatt gcccccggcg caatgccatt
    27841 tacccgaata tttttttcac ccaggtcaaa cgccatattt ctgaccagat gactggccgc
    27901 agctttagat gatgcatagg aagtcatgtt tatattttta ttttctgccg ccatagaagt
    27961 gatggtcaga ataacgccac cgccattttt ttccatttct ggcgcaacaa gttgtgacag
    28021 atggaaaaaa gaaaacacat tcagttcata agcacggcga aaatccgcca ttggcatatc
    28081 aaacggttta ggtccaccgc caccggcgtt gttaaccaga atatcaactt tacccagctt
    28141 actgatagca aagtctgcca gtgcagagag ttcctgttcg gaagtaatat cacaacggca
    28201 ggcaaatgcc tgaccaccca gttgttgaat ttcgtctaca acatggttag ctgcgtcggc
    28261 gttaatatca ctgaccacca cagatgcgcc agctgtcgcg aatgtaatgg cgatttcttt
    28321 accaatacct gcacccgcac ctgtgatgat ggcgcatttt ccgtcgagtc tcaggttgtc
    28381 agaattaaac acataaacct cctgtgaact tcagtaaaaa taaaaggcac cgcctgtgtg
    28441 ccacattttt tatcattaac cttgaggaaa ggacactacc aggtatagca gataaagaga
    28501 ggattatttc gctgcaatga gccgggcggg aataataaga ttgcgtgaat gcgtctcttc
    28561 atgggtgatt ttttgcatca tgcgatccgc aagtgtgata ccaagttccc gcgctggcgt
    28621 gctggcccag gtaacaggta tatcatcaag tgtggttggt gtcgcatcgg taaatgccgc
    28681 cagcgaaacc tgttgctcaa agtaacgatc gactccgctt tccccgcttt gccgccctgc
    28741 tttgagcaaa ccaaaccatg cccccatcgc aatagtttcg ttatagcaaa ccacggcact
    28801 gatggtcggg ttatgacgta aaagcgccgt gatagcttcc gcggcttgct tctggctgga
    28861 agtgcactcc aacacccaat cgctatgaaa cggcaggcca aattttagta gagttgcaca
    28921 atagccccca acccgttctg cacgggttaa tgaggaactt tgccctccca gccaggcgat
    28981 ccgctgatgc ccattgcgaa tgagatgctc cgtcaacaac tgtgcagcct gcatgttgtc
    29041 cgggcgaacc gtatcaacat catcaagata actggcacgg gaagcgaaaa tcaccgggat
    29101 agctttttct tctgccatcc gtcgcaggtc atcgctactt cctgcagctc cggcaattac
    29161 cacaccatcg acaccctgat tcagtaacag tgaaaaccgc tgtgccagct gctcaccgtc
    29221 tttaccgccg tgaagcaaaa aaaccatccg tccctgcgct tccagagctt ccgtcaatcc
    29281 ggccgtcaat tcggcgtaaa acggcgcaga taaatcacgg acgatcaaac caatgacgcc
    29341 gctttgcccg ccgcgcagcg ccgacgcctg gcgattgcgc acaaatccca gctcttcaat
    29401 ggcggcgtta acgcgttctc ctgtggcggt agagattcgc cctttgccac taagcaccag
    29461 cgaaacggta cttaccgaca cgcccgcagc cagcgcaaca tcatgaatgg ttattttttt
    29521 ggcggtagcc atgcagatga cctactccct gattatgtga cagataaaac gttttacctt
    29581 ttatttatct tatacccgct attatcgttg cgtaatgtga tttatgcctc actaaaattt
    29641 gataaaacgt tttatcttct cgcgcaattt actgaatcca gattgttctc tacgaggagt
    29701 cgttttatga cggcgaaaac agcaccgaaa gtcacgctgt gggagttctt ccagcagtta
    29761 ggcaaaacct tcatgttacc cgtggcatta ttgtcgttct gcggcattat gctcggcatt
    29821 ggtagttctc ttagcagcca tgatgtcata accctgatcc cggtcctggg caaccccgtg
    29881 ttgcaggcta tctttacctg gatgagtaag attggctcgt ttgcttttag tttcctgcct
    29941 gtcatgttct gtatcgccat cccgctgggc ctggcacgcg aaaataaagg cgtagcggca
    30001 ttcgctggct tcatcggtta tgcggtaatg aacctcgcgg taaacttctg gttgaccaat
    30061 aaaggcattc tgccaaccac ggatgccgcg gttctgaaag ccaataacat ccagagcatt
    30121 cttgggatcc agtcgatcga taccgggatc ctcggtgcgg tgatcgccgg tattatcgtc
    30181 tggatgctgc atgagcgttt ccataatatc cgcctgccgg atgcgctggc attcttcggc
    30241 ggtacgcgct tcgtaccaat tatctcctcg ctggtgatgg gccttgtcgg cctggtgatt
    30301 ccattagtct ggccgatttt cgccatgggt attagcggct tgggccatat gataaacagc
    30361 gcgggtgatt tcggaccgat gctgtttggt accggtgaac gtctgctgtt gccgtttggt
    30421 ctgcatcaca ttctggtggc attaattcgc tttaccgacg caggcggcac gcaggaagtc
    30481 tgcggtcaaa ccgtcagcgg cgcactgacc atcttccagg cgcaattgag ttgcccgacc
    30541 actcacggtt tttctgaaag cgccacgcgt ttcctttcgc aaggtaaaat gcctgcgttt
    30601 ctcggcggtc tgccaggtgc agcgttagct atgtatcact gcgcgcgccc ggaaaatcgc
    30661 cataaaatta aaggtctgct gatttctggc ctgatcgcct gcgtcgttgg cggcactacc
    30721 gaaccgctgg aattcctgtt cctgttcgta gcgccagttc tgtatgtcat ccacgcgctg
    30781 ttaaccggcc tcggcttcac cgtcatgtct gtgctcggcg tcaccatcgg taataccgac
    30841 ggcaatatca tcgacttcgt ggtgttcggt attttgcatg gtctgtcaac caagtggtac
    30901 atggtgccag tggtggcggc aatctggttt gtcgtttact acgtcatctt ccgtttcgct
    30961 atcacccgct tcaatctgaa aaccccgggg cgcgatagcg aagttgccag ctcaatcgaa
    31021 aaagccgttg ccggtgcgcc gggtaaatca ggttacaacg ttcctgcaat cctcgaagca
    31081 ttaggcggtg ccgacaatat tgtcagcctc gataactgca ttacccgtct gcgtttgtct
    31141 gtgaaagata tgtcgcttgt taatgtgcag gcactgaagg acaatcgggc aattggcgta
    31201 gtacaactta atcaacataa cctgcaggtt gttatcgggc cacaagttca gtcagtaaaa
    31261 gatgaaatgg ccggtctgat gcatactgtc caggcataag gataagatat gttcgatttt
    31321 tcaaaggtcg tggatcgtca tggcacatgg tgtacacagt gggattatgt cgctgaccgt
    31381 ttcggcactg ctgacctgtt accgttcacg atttcagaca tggattttgc cactgccccc
    31441 tgcattatcg aggcgctgaa tcagcgcctg atgcacggcg tatttggcta cagccgctgg
    31501 aaaaacgatg agtttctcgc ggctattgcc cactggtttt ccacccagca ttacaccgcc
    31561 atcgattctc agacggtggt gtatggccct tctgtcatct atatggtttc agaactgatt
    31621 cgtcagtggt ctgaaacagg tgaaggcgtg gtgatccaca cacccgccta tgacgcattt
    31681 tacaaggcca ttgaaggtaa ccagcgcaca gtaatgcccg ttgctttaga gaagcaggct
    31741 gatggttggt tttgcgatat gggcaagttg gaagccgtgt tggcgaaacc agaatgtaaa
    31801 attatgctcc tgtgtagccc acagaatcct accgggaaag tgtggacgtg cgatgagctg
    31861 gagatcatgg ctgacctgtg cgagcgtcat ggtgtgcggg ttatttccga tgaaatccat
    31921 atggatatgg tttggggcga gcagccgcat attccctgga gtaatgtggc tcgcggagac
    31981 tgggcgttgc taacgtcggg ctcgaaaagt ttcaatattc ccgccctgac cggtgcttac
    32041 gggattatag aaaatagcag tagccgcgat gcctatttat cggcactgaa aggccgtgat
    32101 gggctttctt ccccttcggt actggcgtta actgcccata tcgccgccta tcagcaaggc
    32161 gcgccgtggc tggatgcctt acgcatctat ctgaaagata acctgacgta tatcgcagat
    32221 aaaatgaacg ccgcgtttcc tgaactcaac tggcagatcc cacaatccac ttatctggca
    32281 tggcttgatt tacgtccgtt gaatattgac gacaacgcgt tgcaaaaagc acttatcgaa
    32341 caagaaaaag tcgcgatcat gccggggtat acctacggtg aagaaggtcg tggttttgtc
    32401 cgtctcaatg ccggctgccc acgttcgaaa ctggaaaaag gtgtggctgg attaattaac
    32461 gccatccgcg ctgttcgtta accccaattg cgcaacgtaa aaaatcgttg cgcaatcgtg
    32521 gatttttacc ctgctttgtt tttataatgg tgcgcacttt tatatccaga aaaagagtgc
    32581 gaccatgatt gataccaccc tgccattaac tgatatccat cgccaccttg atggcaacat
    32641 tcgtccccag accattcttg aacttggccg ccagtataat atctcgcttc ctgcacaatc
    32701 cctggaaaca ctgattcccc acgttcaggt cattgccaac gaacccgatc tggtgagctt
    32761 tctgaccaaa cttgactggg gcgttaaagt tctcgcctct cttgatgcct gtcgccgcgt
    32821 ggcatttgaa aacattgaag atgcagcccg tcacggcctg cactatgtcg agctgcgttt
    32881 ttcaccaggc tacatggcaa tggcacatca gctgcctgta gcgggtgttg tcgaagcggt
    32941 gatcgatggc gtacgtgaag gttgccgcac ctttggtgtg caggcgaagc ttatcggcat
    33001 tatgagccgg accttcggcg aagccgcctg tcagcaagag ctggaggcct ttttagccca
    33061 ccgtgaccag attaccgcac ttgatttagc cggtgatgaa cttggtttcc cgggaagtct
    33121 gttcctttct cacttcaacc gcgcgcgtga tgcgggctgg catattaccg tccatgcagg
    33181 cgaagctgcc gggccggaaa gcatctggca ggcgattcgt gaactgggtg cggagcgtat
    33241 tggacatggc gtaaaagcca ttgaagatcg ggcgctgatg gattttctcg ccgagcaaca
    33301 aattggtatt gaatcctgtc tgacctccaa tattcagacc agcaccgtag cagagctggc
    33361 tgcacatccg ctgaaaacgt tccttgagca tggcattcgt gccagcatta acactgacga
    33421 tcccggcgta cagggagtgg atatcattca cgaatatacc gttgccgcgc cagctgctgg
    33481 gttatcccgc gagcaaatcc gccaggcaca gattaatggt ctggaaatgg ctttcctcag
    33541 cgctgaggaa aaacgcgcac tgcgagaaaa agtcgccgcg aagtaacaaa atggatggtg
    33601 caaatgcacc atccattttt catgcaaggc acaaagtcgc gcgatgtttg gcggattcga
    33661 tgcccagctc aatcaactcc attacctgga ttgcctggct tgccggaacc ggattttcac
    33721 catcgccatt taacgcatca cgaatagccg catagtaagc cggataattc ccaggcaccg
    33781 tcaacagcgt ttcttcgaca cgttcctcac cttccacgcg ggtaagtacg ccatcacgca
    33841 tatcgtagcc ccagtcttcc tgcggtagac gctcgccatt tttcagacgt tcttcctgtg
    33901 gatcgaggcc atatttcaca taactgcctc gggatccatg cacgatatac cgtgctgact
    33961 cagcggctgc cagcatggta ccgtgtaaaa tgactcgccg ctgtggatag gacaagatgg
    34021 cgtggaaata atcggtcgac tgcgctccgg gccgtaactg tgccaaatct accgtcatgc
    34081 tgaccggtaa accaaaaagc gtaatggcct gatcaagaag atgtggtgct aaatcgtacc
    34141 agataccgct gcctgggccg ccctgttcac gccaacgatc gcgcacctgc ggacggaagc
    34201 ggtcaaaatg agactcaaag taagcaactt cacccagcac gccttccgcg agtaaacctt
    34261 ttagcgtcaa gaaatcgcta tcccagcgac ggttatggaa tacagacagc acacgcccca
    34321 ggctttttgc cagcgcatcc agctctcgcg cttgtgacag tgtcacggta aagggtttat
    34381 caacgaccac atgtttaccc gcctcaagcg ccgctttggc taacgggaaa tgggtatcgt
    34441 tgggtgtagg aatgacaatc aggtctatgt tgggatcgtt aaacagatgc ttcggctcag
    34501 agacaaccgt aaccgttggc cagtcggctt ttacttttgt ttcatcactg ctggagatta
    34561 ccgccagttc cagcccgggc gtgcccgcaa tcaggggcgc atggaaggtt ttgctcgcat
    34621 aaccataccc aatcaaccca acacggatgt tgtcgctcat gtcattgcct ctcattgaag
    34681 tatgatggct atttgacact atcctttacc cacgctcaac agtttaataa cctgccagca
    34741 ataagggatg ttgtttaact taagtcaaaa aaatagcgaa ttttccaacg acaaaagcta
    34801 aatatcgcaa aaacctcagt aaaaatcttg ctggagctat tattgctaag taacatttac
    34861 cccctgaagt taatggatca atcaagagag atgtgggctg taatgaatcg tcttattgaa
    34921 ttaacaggtt ggatcgttct tgtcgtttca gtcattcttc ttggcgtggc gagtcacatt
    34981 gacaactatc agccacctga acagagtgct tcggtacaac acaagtaagc tctgcacttg
    35041 tggagcgaca tgctgcccgt ccgggtgcat gttttcactt gtcggatatt aaaccaggaa
    35101 tttattatct tgttcgatgt tgttggtgat tgtcagggat agtaaagcgc gttactcttt
    35161 tcagagcagt ttttcatccc tgaatatttg ccatcagcgc attcttatta ttgtaataac
    35221 acaagcgttc acttttggtg aaa
//
LOCUS       DAPHKZ010000041        34180 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.041, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000041 DAPHKZ010000000
VERSION     DAPHKZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34180
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.041"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(86..1216)
                     /gene="dnaJ"
                     /locus_tag="RH288_002068"
     CDS             complement(86..1216)
                     /gene="dnaJ"
                     /locus_tag="RH288_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDV4031117.1"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     gene            complement(1305..3221)
                     /gene="dnaK"
                     /locus_tag="RH288_002069"
     CDS             complement(1305..3221)
                     /gene="dnaK"
                     /locus_tag="RH288_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDV4031118.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            3598..4002
                     /locus_tag="RH288_002070"
     CDS             3598..4002
                     /locus_tag="RH288_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HDV4031119.1"
                     /translation="MKSVFTISASLAISLMLCCTAQANDHKLLGVIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     gene            4028..4741
                     /gene="msyB"
                     /locus_tag="RH288_002071"
     CDS             4028..4741
                     /gene="msyB"
                     /locus_tag="RH288_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HDV4031120.1"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKNMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     gene            4890..5456
                     /gene="satP"
                     /locus_tag="RH288_002072"
     CDS             4890..5456
                     /gene="satP"
                     /locus_tag="RH288_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HDV4031121.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     gene            complement(5491..6078)
                     /gene="mog"
                     /locus_tag="RH288_002073"
     CDS             complement(5491..6078)
                     /gene="mog"
                     /locus_tag="RH288_002073"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HDV4031122.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAAGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE"
     gene            complement(6193..7146)
                     /gene="tal"
                     /locus_tag="RH288_002074"
     CDS             complement(6193..7146)
                     /gene="tal"
                     /locus_tag="RH288_002074"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDV4031123.1"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPTLLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL"
     gene            7425..8855
                     /locus_tag="RH288_002075"
     CDS             7425..8855
                     /locus_tag="RH288_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDV4031124.1"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDANGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     IQANAVARALSFSFDFPPLVTGIILAVFALLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPDIGRQLSPDAWDDVSQE"
     gene            8925..9701
                     /gene="yaaA"
                     /locus_tag="RH288_002076"
     CDS             8925..9701
                     /gene="yaaA"
                     /locus_tag="RH288_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDV4031125.1"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPP
                     QISTLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
     gene            complement(9854..10150)
                     /locus_tag="RH288_002077"
     CDS             complement(9854..10150)
                     /locus_tag="RH288_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HDV4031126.1"
                     /translation="MKKMQSIVLALSLVLVAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPHGPPPPPRHHKKAHHDHHGGHGPGKHHR"
     gene            complement(10364..11650)
                     /gene="thrC"
                     /locus_tag="RH288_002078"
     CDS             complement(10364..11650)
                     /gene="thrC"
                     /locus_tag="RH288_002078"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDV4031127.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     gene            complement(11651..12583)
                     /gene="thrB"
                     /locus_tag="RH288_002079"
     CDS             complement(11651..12583)
                     /gene="thrB"
                     /locus_tag="RH288_002079"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDV4031128.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAEIF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     gene            complement(12585..15047)
                     /gene="thrA"
                     /locus_tag="RH288_002080"
     CDS             complement(12585..15047)
                     /gene="thrA"
                     /locus_tag="RH288_002080"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HDV4031129.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHLLRHAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDRFAARVAKARDEG
                     KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    complement(15074..15193)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            complement(15129..15194)
                     /gene="thrL"
                     /locus_tag="RH288_002081"
     CDS             complement(15129..15194)
                     /gene="thrL"
                     /locus_tag="RH288_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HDV4031130.1"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            complement(15408..16094)
                     /locus_tag="RH288_002082"
     CDS             complement(15408..16094)
                     /locus_tag="RH288_002082"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HDV4031131.1"
                     /translation="MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAHLEPAT
                     RWVAHGSGDIIDNIKVFPTLVESLHDVDFTVATTARSRAKYHYYATPVELVPLLEEKS
                     SWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLATLIQ
                     QPTKSDTTADQHQLQALRERVMALLTTLAVADDIKLVDWLQQRLGLLEQRDTAMLHRL
                     LHDIEKNITK"
     gene            complement(16494..16634)
                     /locus_tag="RH288_002083"
     CDS             complement(16494..16634)
                     /locus_tag="RH288_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031132.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILT
                     AT"
     gene            16730..17446
                     /gene="arcA"
                     /locus_tag="RH288_002084"
     CDS             16730..17446
                     /gene="arcA"
                     /locus_tag="RH288_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HDV4031133.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLED"
     gene            complement(17506..18858)
                     /gene="creD"
                     /locus_tag="RH288_002085"
     CDS             complement(17506..18858)
                     /gene="creD"
                     /locus_tag="RH288_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HDV4031134.1"
                     /translation="MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDA
                     IRQSTSGPQKLVGPLIAIPVTELYTVQEEDKTVERKRSFIHFWLPESLMVDGNQNVEE
                     RKIGIYTGQVWHSDLTLKADFDVSRLSELNAPNIILGKPFIVISVGDARGIGVVKAPE
                     VNGTALTIEPGTGLEQGGQGVHIPLPEGDWRKQNLKLNMALNLSGTGDLSVVPAGRNS
                     EMTLTSNWPHPSFLGDFLPAKREVSESGFQAQWQSSWFANNLGERFASGNDTGWENFP
                     AFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHIGFTVAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLALLLLDGVM
                     WGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTMDDQLRIWK
                     "
     gene            complement(18916..20340)
                     /gene="creC"
                     /locus_tag="RH288_002086"
     CDS             complement(18916..20340)
                     /gene="creC"
                     /locus_tag="RH288_002086"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HDV4031135.1"
                     /translation="MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLID
                     TATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDSQG
                     KVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
                     IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYAD
                     SVTDNKPVPLPELGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTVVDVAALF
                     RRVSEARTVQLAEKNITLHVMPTEVNVAAEPALLEQALGNLLDNAIDFTPESGRITLS
                     AEVDQEHVALKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFN
                     GEVTLRNVQEGGVLASLRLHRHFT"
     gene            complement(20340..21029)
                     /gene="creB"
                     /locus_tag="RH288_002087"
     CDS             complement(20340..21029)
                     /gene="creB"
                     /locus_tag="RH288_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HDV4031136.1"
                     /translation="MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKAR
                     QQAPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYV
                     AKPFSPREVCARVRTLLRRVKKFSSPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
                     LLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTIDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRGL"
     gene            complement(21042..21515)
                     /gene="creA"
                     /locus_tag="RH288_002088"
     CDS             complement(21042..21515)
                     /gene="creA"
                     /locus_tag="RH288_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HDV4031137.1"
                     /translation="MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDRIKNGKAQGE
                     VVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ"
     gene            21726..22595
                     /gene="robA"
                     /locus_tag="RH288_002089"
     CDS             21726..22595
                     /gene="robA"
                     /locus_tag="RH288_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HDV4031138.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
                     YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVM
                     LQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRP
                     INLRCELLIPIRR"
     gene            complement(22592..23239)
                     /gene="gpmB"
                     /locus_tag="RH288_002090"
     CDS             complement(22592..23239)
                     /gene="gpmB"
                     /locus_tag="RH288_002090"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HDV4031139.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAK
                     ELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEEN
                     WRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR"
     gene            23291..23812
                     /gene="yjjX"
                     /locus_tag="RH288_002091"
     CDS             23291..23812
                     /gene="yjjX"
                     /locus_tag="RH288_002091"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/xanthosine triphosphatase"
                     /protein_id="HDV4031140.1"
                     /translation="MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQ
                     PFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSA
                     TLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVIL
                     ALSPFHNAVYQAL"
     gene            complement(23897..24223)
                     /gene="trpR"
                     /locus_tag="RH288_002092"
     CDS             complement(23897..24223)
                     /gene="trpR"
                     /locus_tag="RH288_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HDV4031141.1"
                     /translation="MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLT
                     PDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEE
                     VLLKSD"
     gene            complement(24313..26250)
                     /gene="sltY"
                     /locus_tag="RH288_002093"
     CDS             complement(24313..26250)
                     /gene="sltY"
                     /locus_tag="RH288_002093"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HDV4031142.1"
                     /translation="MEKAKQVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGPMPADYQTIASAI
                     ISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNED
                     HIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYE
                     LKIDKAPQNVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYA
                     FNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSYLQYVYQ
                     QFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRYFMGDKPTLMSATEWGRRY"
     gene            26461..28128
                     /gene="ettA"
                     /locus_tag="RH288_002094"
     CDS             26461..28128
                     /gene="ettA"
                     /locus_tag="RH288_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HDV4031143.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
                     ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWV
                     RQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
                     DRLLIDDLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVD
                     QFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK"
     gene            complement(28435..29667)
                     /gene="nadR"
                     /locus_tag="RH288_002095"
     CDS             complement(28435..29667)
                     /gene="nadR"
                     /locus_tag="RH288_002095"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418807.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HDV4031144.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDD
                     TRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIETVLVDPKRTFMSISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     IALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEDDYD
                     SRFLRCVELVREMMGEQR"
     gene            complement(29688..31070)
                     /gene="radA"
                     /locus_tag="RH288_002096"
     CDS             complement(29688..31070)
                     /gene="radA"
                     /locus_tag="RH288_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDV4031145.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKAPEGMQIFGVKKL
                     SDALSVFDDL"
     gene            complement(31119..32087)
                     /gene="serB"
                     /locus_tag="RH288_002097"
     CDS             complement(31119..32087)
                     /gene="serB"
                     /locus_tag="RH288_002097"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HDV4031146.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLRS
                     RVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKL
                     RLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGAND
                     LPMIKAAGLGIAYHAKPKVNEKTEVTIRHADLMGVFCILSGSLNQK"
     gene            32193..32837
                     /locus_tag="RH288_002098"
     CDS             32193..32837
                     /locus_tag="RH288_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HDV4031147.1"
                     /translation="MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIAR
                     SGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKE"
     gene            32865..33881
                     /gene="lplA"
                     /locus_tag="RH288_002099"
     CDS             32865..33881
                     /gene="lplA"
                     /locus_tag="RH288_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HDV4031148.1"
                     /translation="MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     SIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEVITKAFFAHYGERVEA
                     EIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFSWGGVELHFDVEKGHI
                     TRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPDQEKELRELSTWIA
                     GAVR"
     gene            33913..34176
                     /locus_tag="RH288_002100"
     CDS             33913..34176
                     /locus_tag="RH288_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV4031149.1"
                     /translation="MIDLENQEREIINLMLSQRISWLAAVRIRHKLSLAEVSKMLGIS
                     INSLKQIEKTERLSSNIKSKMAEIYGCPPELLICPSWMTAEHK"
BASE COUNT         8038 a         9322 c         8533 g         8287 t
ORIGIN      
        1 atccccgcca cttttcaggt gctcgcatat cttcaacgca ccctggtttt acccaggcct
       61 gcccacgggc aggcttttgg ggaggttagc gggtcaggtc gtcaaaaaac ttcttcacac
      121 catcaaagaa gctctttgag cgcgggctgt tgtgctcgcc ggttgggcca ccgaagcttt
      181 cttgcagctc ttgcagcagc tgtttctgct tctcgttcag gcctaccggt gtttcgacga
      241 caacgcggca cagcaaatca ccctgtgcgc caccgcggac agacttgacg cctttaccgc
      301 gcatacggaa aagcttaccg gtctgggttt cgccaggcac tttcagtttg acgcgaccat
      361 caagggtcgg tacttcgatt tcgccaccca gcgccgccat agcgaagttg atcgggactt
      421 cgcaatacag gttgttgcct tcacgctcga aaatcgggtg ctgtttaacc tgaacctgaa
      481 cgtacagatc gcctgccggt gcgccatgct cgcccgcttc accttcgccc gcaagacgga
      541 tgcggtctcc agtgtccact cctgccggga ttttaacgga cagcgttttg ctgcgctcaa
      601 cacgaccatg accatgacat ttgttgcacg gatctttgat cagcgtaccg cggccctgac
      661 agtgtggaca ggtctgctgt acagcgaaga atccctgacg catctgcacc tgaccagaac
      721 catgacaggt cggacaggtc tgcggctgtg tacctggttt tgcaccgcta ccgtggcaaa
      781 cgtcacactc ttccagagtc ggaatgcgga tctctttggt cacgccacgt acagcttctt
      841 cgagggtgag ctccatgtta tagcgtaaat cagcaccgcg cgccgcacgt tgacgaccac
      901 gtccgccgcc aaaaatatcg ccgaaaacgt caccaaaaat atcgctgaag tctgcgccgc
      961 cgccaaaacc gccgccgccc ataccacctt gctcaaacgc agcatgacca tactgatcgt
     1021 atgccgcacg tttttgcgag tcggtcagaa cttcataagc ttccttgatc tctttaaatt
     1081 tcgcctcggc ctctttgtca ccctggttac ggtccgggtg gtatttcatg gccaggcgtt
     1141 tgtaggcctt tttgatttca cgctcttccg ctgttttgga aacgcctaaa atctcgtaat
     1201 aatcttgctt agccatcttt tttaaattgc ccctagatga atgcacgggc ggagaggaaa
     1261 ttccccttcg cccgtgtcag tataattacc cgtttatagg gcgattattt tttgtctttg
     1321 acttcttcaa attcagcgtc gacaacatcg tcatctttcg cgttgtttgc agaagcatca
     1381 gcaccggcag tctgctgctg ggcatgttgc tgctgggcga tttccatcag tttctgggaa
     1441 acctgtgcca gttcctgcat tttcgcttcg atagcggctt tgtcttcacc tttcagagca
     1501 gtttccagtg cagtcagtgc agactcgata gcagttttgt cgtcagccgg cagtttgtcg
     1561 cctgcttctt caacctgctt acgggtgctg tgcagcagat ggtcgccctg gttgcgagtc
     1621 tgtaccagct cttcaaactt acggtcagct tcggcgttag cttctgcgtc gcgtaccatt
     1681 ttctggattt catcttcgtt cagaccagaa gaagccttga tggtgatctt ctgctcttta
     1741 ccgctgtttt tatctttcgc ggaaacgtgc aggataccgt cagcatcgat atcgaaggta
     1801 acttcgatct gcggcatgcc gcgcggtgcc gggttgatac catccaggtt gaactgaccc
     1861 agagatttgt tatcagccgc acgtttacgt tcaccctgca gcacatggat ggttaccgca
     1921 gactggttgt cttcagcggt agagaacacc tggctgtgct tggtcgggat agtggtgttt
     1981 ttcgcgatca gcgtcgtcat cacaccgccc atggtttcga tacccagaga cagcggggta
     2041 acgtccagca gcagtacgtc tttcacgtca ccagtcagaa caccaccctg aacagcagca
     2101 ccgattgcta cagcttcgtc cgggttaacg tctttacgcg gctctttacc aaagaactca
     2161 gcaactttct tctgaaccat tggcatacga gtctgaccac caacgaggat aacgtcgtcg
     2221 atatcagata cggacaggcc agcgtcctgc agtgcaactt tcagcggctc aatggaacgg
     2281 tttaccagat cttcaaccag gctttccagt ttcgcacgag tcactttgat gttcatgtgt
     2341 ttcggaccgg tcgcatctgc agtgatgtac ggcaggttaa cgtcggtctg ctgagcggaa
     2401 gacagttcga ttttcgcttt ttctgccgct tctttcaggc gctgcattgc cagcggatcg
     2461 ttgcgcaggt caatgccctg atctttcttg aattcttcaa ccaggtagtt gatcagacgg
     2521 ctgtcgaagt cttcaccacc caggtgggta tcaccgttgg ttgccagaac ttcgaaggtt
     2581 ttttcgccgt caacttcgtc gatttcgata atagaaatat cgaaagtacc accacccagg
     2641 tcataaaccg cgatagtacg gttgccagta cctttgtcca gaccgtaagc cagcgcagct
     2701 gcggtcggtt cgttgatgat acgttttact tccagaccag cgatacggcc tgcgtctttg
     2761 gttgcctgac gctgagcatc gttaaagtat gccggtacgg tgataacagc ttcagttacc
     2821 ggttcaccca ggtaatcttc agcggttttc ttcatttttt tcagcacttc agcagagatc
     2881 tgcggcggtg ccattttctg gcctttaact tcgacccatg cgtcgccgtt atcagcagca
     2941 ataattttga acggcatgat ggaaacatca cgctgtactt cttcgtcctg gaagcggcgg
     3001 ccaatcaggc gtttaatcgc aaacagggtg ttttgcgggt tcgtcactgc ctgacgttta
     3061 gccggctgac caaccagagt ttcaccatcc tgggtatagg caatgataga aggcgtggtg
     3121 cgatcgcctt cggcgttctc cagcacacga ggagtggtgc catccataat cgctacacaa
     3181 gagttggtag tacccaggtc gataccaatt attttaccca tctaaacgtc tccactatat
     3241 attcggtcat catgtggttg tgagtctgta ataggggcga aacgtctggt ttcaactgcc
     3301 caatttcatt tttttgcaga ctcactcact gcggttgact actaaatggg gtcgtaaccc
     3361 acgtcatcaa gggggagatg caaaaatttt ttgtgctttt gcgcagaaat ttcgcgatat
     3421 ggcaggacaa gacgtaaaat tgacagcaat tttattcaga taaagaatga atcgcagcca
     3481 aggcattcat caaaaaattg taataaaaag aaaagattac gtacctgaac cttctcttta
     3541 tcagcagtaa actagtgggt attcatccct ctacctcttc ccactaagag aatccttatg
     3601 aaatccgttt ttacgatttc cgccagcctg gcgattagcc tgatgctgtg ctgcacggcg
     3661 caggcaaacg accataaact cctcggcgtc attgcaatgc cgcgtaacga aaccaacgat
     3721 ctggcgctga aacttcctgt ttgtcgcatt gtgaaacgca tacaactctc tgccgaccat
     3781 ggcgatttac agttaagcgg tgcatcggtt tatttcaaag ccgcccgtag cgccagtcag
     3841 agtctgaata ttccttcaga aataaaagaa gggcaaacca ctgactggat caacattaac
     3901 agtgataacg acaataaacg ctgcgtctca aaaatcacct tttccggtca tacggtgaac
     3961 tcatcggata tggccacgct gaaaattatc ggcgacgact aacgccagaa tatagaaacc
     4021 acaaaaaatg aatgttaatt acctgaatga ttcagatctg gattttcttc agcattgtag
     4081 tgaggaacag ttggcaaatt tcgcccgatt gctcacccat aatgaaaaag gcaaaactcg
     4141 cctctccagc gtactgatgc gcaacgaact gtttaaatcg atggaagggc atcccgagca
     4201 acatcgccgc aactggcagc tgattgctgg agaattacag cattttggtg gcgatagtat
     4261 cgccaacaaa ctgcgcggac acggtaaatt gtatcgggcc attttgctcg atgtttcaaa
     4321 acgattgaag ctgaaagccg acaaagagat gtctacgttt gagattgagc aacagttact
     4381 ggaacaattt ctgcgtaaca cctggaagaa tatggacgag gaacataagc aggagtttct
     4441 gcacgcggtc gatgccaggg tgaatgagct ggaagagctg ctgccgctgc tgatgaaaga
     4501 caaattattg gcaaaaggcg tgtcgcattt gctttccagc caattgaccc gcattttacg
     4561 cacccacgca gcaatgagcg tgcttgggca tggtttgctg cgcggcgcgg gtctgggagg
     4621 ccctgtgggc gcagcattaa atggggttaa agcggtcagc ggcagtgcct atcgcgtgac
     4681 aattccagcc gtactgcaaa tcgcctgcct gcgccggatg gttagcgcca ctcaggtctg
     4741 acaccgtaaa ccggggaaaa ttttcatttt cccctcaaaa gatcgtagac actgccccac
     4801 tggctgatta ttatgccgcg ccctgaaaac actactgtta ttcagggaaa ttatttcacc
     4861 attcattcga tgatgatttt tgaggaatta tgggcaacac taagttggct aatccggcac
     4921 cgctgggcct gatgggcttc ggcatgacca ccattctgct taacctgcac aacgtgggtt
     4981 atttcgctct ggacggtatt attcttgcca tgggcatttt ctacggcggc atcgcgcaaa
     5041 tttttgccgg tctgctggag tacaaaaaag gcaacacttt cggtttaacc gcattcacct
     5101 cttacggttc tttctggctg acgttggttg cgattctgct gatgccgaaa ctgggtctga
     5161 ccgatgcgcc aaatgcacag ttccttggtg tctacctggg tctgtggggc gtatttacgc
     5221 tgtttatgtt cttcggcacg ctgaaaggcg cacgcgttct gcaattcgtt ttctttagcc
     5281 tgactgtgct gtttgccctg ctggcgatcg gtaacattgc cggtaacgcc gcaatcatcc
     5341 actttgccgg ctggattggt ctgatctgtg gtgccagtgc aatctatctg gcgatgggtg
     5401 aagtactgaa cgagcagttt ggtcgcaccg ttctgccgat tggtgaatcc cactaattgt
     5461 tttgagatcc ccccgctcgg ggggattttt ttattcgcta acgtcgcgtc ttgcactctt
     5521 cggtctgaat gcagcaacca cttctggtgc cgtttcaacg tatggccctt ccagcaactg
     5581 aatgcagtac ggtacgctgg caaaaatacc gtgtaccaca acgttacccg cagcgtcctt
     5641 cacaccttcc agcgtctctt taatagactt cggctgaccg ggtaagttaa ggatcagcgc
     5701 ctgtttgcga atcacaccaa cctgacgcga aaggatcgca gttggtacaa aatgcaggct
     5761 tatctggcgc atctgttcac caaagccagg catctcgcgg tccgctactg ccagcgtcgc
     5821 atcgggcgtt acgtcacgac gcgccgggcc agttccgccc gtggtgagca ccagatggca
     5881 actcatttca tccactagct cacacaacgt ttgctcgatg atcgcctgct catcggggat
     5941 taagcgggtt tccagttcaa acggcgtggt tagcgccgat gtcagccatt cttccagcgc
     6001 agggatgcct ttatcctgat aaacgccgct ggatgcgcga tcagagatgg aaactaagcc
     6061 aatacgtaaa gtattcatca agatttttcc gtttaaacag tctcgttaaa cagaatgata
     6121 cactgcgaag ggagtgacag acaggcttca gaagaggtag cgtgaccgac ttcccggtca
     6181 cgctaagaat gattacagca gatcgccgat cattttttcc agtttttcct ggtcaatagc
     6241 aaacttacgg ataccttccg ccagtttatc tactgccatt ggatcctggt tgtgctgcca
     6301 caggaactcg gactcagtga tacgcgccgg acgcgctttc acttcgccgg tgtaagacag
     6361 tttacgttcg atagcccctt cgctctcagc cagctctttc agcagtgtag gtgcgatggt
     6421 aagacggtcg cagcctgcca gttccagaat ttcgccgatg ttacggaagc ttgcgcccat
     6481 aaccacggtt tcataaccgt gctctttgta gtactggtag atttcagata cagaaaccac
     6541 gcccggatct tctgccggag cgtactcttt cttatcggta ttcgctttgt accagtcaag
     6601 aatacggcca acaaacggcg agatcaggaa cacgcccgct tccgcacaag cacgagcctg
     6661 agcgaaggag aacagcaggg tcaggttaca gttgatgcct tctttttcca gctgttctgc
     6721 agcacggata ccctgccagg tagaagccag tttgatcaga atacgatcgt tgctaatacc
     6781 agcatcgttg tagagtttga tcaggcgttt tgctttcgca attgacgctt cggtgtcata
     6841 ggaaagacgc gcatcaactt cagttgagat acggcccgga accagtttca ggatttccag
     6901 accaatattt actgccagtt tgtcggtcgc gtccacgatc tgctgcgcgc gatcgttgct
     6961 ctgctgtttc gcccaggcga cagcatcatc aatcaactta cggtattccg gaatctgcgc
     7021 tgcgttaaga atgagagaag ggttggttgt ggcatcctgc ggttgataca gcttcattgc
     7081 cgcgatgtcc ccagtgtcgg ccactacggt ggtgtactga cgaagggagg tcaatttgtc
     7141 cgtcatgata gtatttctct ttaaacagct tgttaggggg atgtaaccgg tctgccctga
     7201 tgatatcacg acgcaacgtc agcgcaaccg ccgacaagac ggttatcgcc aggcgagact
     7261 gtttcggatt tctgacactg cgttgatatc gcccgccatt tttatacaaa acctcatgta
     7321 tgctacgcag aagttatcaa gtacctcgta gcgtatatac ttcttaaaca attggtaacg
     7381 tttacacagg aaagtcatcg cgaccggcaa taagagggat atgcatgcca gattttttct
     7441 cctttattaa cagcgtcctt tggggatcgg taatgattta cctgctcttc ggcgcaggtt
     7501 gttggttcac ttttcgcacc ggatttgtgc agtttcgcta catccgccag tttggcaaaa
     7561 gtcttaaaaa tagcattcat ccacagccag gcggtttaac ctcatttcag tcattgtgta
     7621 ccagtcttgc ggcgcgcgtg ggtagcggca acctggccgg cgttgcgctg gcaattaccg
     7681 ccggtggacc tggagccgtc ttctggatgt gggttgccgc gtttatcggc atggcgacct
     7741 cgtttgccga atgttccctc gcacagcttt ataaagaacg tgatgccaat gggcagtttc
     7801 gtggcggacc ggcatggtat atggcgcgcg ggctggggat gcgctggatg ggcgttctgt
     7861 tcgccgtctt tttgctcatc gcctacggca taattttcag cggaattcag gcgaacgccg
     7921 ttgcgcgagc cctgagtttt tcttttgatt ttcccccgct ggtgacaggt attattctcg
     7981 ctgtctttgc tctgctggcg atcactcgcg gtcttcatgg cgtcgcccgg ctcatgcagg
     8041 ggtttgtccc gttgatggcg ataatctggg tactgaccag cctggtgatt tgcgtaatga
     8101 atatcgggca acttccccac gtcatttggt ctatttttga gagtgctttt ggctggcagg
     8161 aagcggcagg cggcgcggcg ggatatacct taagccaggc gattactaac ggttttcagc
     8221 gcagtatgtt ttccaatgag gcgggaatgg ggtcgacgcc aaacgcggca gcggcagcgg
     8281 cgtcctggcc tccgcatccg gcagcgcaag ggattgtcca gatgattggc atttttatcg
     8341 acaccctggt catctgtacg gcaagcgcca tgctgatatt actggcgggt aacggcacaa
     8401 cctacatgcc gctggaaggt attcagctta tccagaaggc gatgcgggtg ctaatgggtt
     8461 cctggggtgc tgagtttgtt accctcgtgg ttattctgtt tgccttcagc tccatcgttg
     8521 ccaactacat ttacgccgaa aacaatctct tctttttacg cctgaacaac cctaaagcga
     8581 tctggtgttt gcggatctgc accttcgcaa cggtcatcgg cggcaccttg ctaagtcttc
     8641 cgctgatgtg gcaactggca gatatcataa tggcctgcat ggctattacc aatttgaccg
     8701 ccattttact gctctcgcct gtggttcata ccattgccag tgattatcta cgccagcgta
     8761 aactcggcgt gcgcccggtg tttgatccgt tgcgttatcc ggatatcggc cgccagcttt
     8821 ctccggacgc gtgggatgat gtttcgcagg agtaatcaca actatcgatc aactcattct
     8881 ctttttttgc taaagtcggc ataaatttcc tgcaaggact ggatatgctg attcttattt
     8941 cacctgcgaa aacgcttgat taccaaagcc cgttgaccac cacgcgctat acgctgccgg
     9001 agctgttaga caattcccag cagttgatcc atgaagcgcg gaaactgacg cctccgcaga
     9061 ttagcacgct gatgcgcatc agcgacaaac tggcgggtat caacgccgct cgctttcatg
     9121 actggcagcc agatttcacg ccggagaatg cccgccaggc gattctggcg tttaaaggtg
     9181 atgtctacac cggcttgcag gccgaaacct tcagcgaaga cgatttcgat tttgcccaac
     9241 agcatttgcg aatgctttcc ggcttgtatg gcgtactgcg cccgctcgat ttaatgcagc
     9301 cttatcgtct ggaaatgggg atccgtcttg agaatgcccg agggaaagat ctgtatcaat
     9361 tctggggaga tatcatcacc aacaagctga acgaggcgct cgcagcacaa ggcgataatg
     9421 tggtgattaa tctggcgtca gatgagtatt ttaaatcggt gaagccgaag aaattgaatg
     9481 ccgagattat caagccggtg ttcctcgatg agaagaacgg caaatttaag ataatcagct
     9541 tctacgctaa gaaagcacgc ggtctgatga gtcgttttat tattgaaaat cggctgacca
     9601 aaccagagca actgactggt tttaatagcg aaggttactt ctttgatgaa gcttcctcca
     9661 gcaatggcga actggtgttt aaacgctacg agcagcgtta agtttgcagt caatgccgga
     9721 tgcggcgtga acgccttatc cggcctacaa aagcatgcag attcaatata ttgcagaatt
     9781 cacgtaggcc tgataagacg cgccagcgtc gcatcaggcg ctgaatgccg gattgttacc
     9841 cggcatttgt catttagcgg tgatgtttgc ctggaccatg accgccgtga tgatcatgat
     9901 gagctttctt atggtgacgc ggcggtggcg gcggtccgtg tgggtgccag cgattgcctc
     9961 gccattcata atgttgtttc caccagccgt ggtcgcgcca gtgaccgcca tcccagtaat
    10021 aaccgcgatt atcacgatcg cctatctgta attttactga cgggactaac gtaatttccg
    10081 cagcctgcgc tgccatggga gcgaccagaa ccagggaaag tgcgagtacg atagattgca
    10141 tctttttcac aggttactcc ttttatcatt gcccgttatg ggtcgatatc cggagattac
    10201 gcgatgagaa cggcggttgt tattctccgc aatcctaatc tctaagttac cgcatttatt
    10261 gagaatttct cctttttccc tgtcgtttct ctccatattt tcttcacaaa aaagccgggc
    10321 tgcataaaag caaacccggc ctgattgaga taatgaatag atgttactga tgattcatca
    10381 tcaatttacg caacgcagca aaatcggcgg gcagattatg tgaaagcaag ggtaaatcag
    10441 cacgttctgc cagctctttt ggcagatcca acgtttcacc gagaatcgct tccacgctct
    10501 ctttaaattt cgccggatgc gcggtgccga ggaacaagcc atattcgcct ggattcaact
    10561 ggtcacgcag cgcacgatac gctacggcag cgtgcggctc cgaggtgtag cccagttctt
    10621 ttaactcacg cattgtctgt tgcgtggttt catcatccac ggctgcataa cccagctctt
    10681 tcagttgcca gattttgcgg cggaacaact cttccacacg cggccagttg ttcggctgac
    10741 tcacgtccat cgcgttggat aacgtcgcct gagtcgcttt gggggaccac tgaccgtcgt
    10801 gcaggaaacg tggcacggta tcgttcacgt tggtcgcagc aataaaacgt ttcaccggca
    10861 gaccgagtga cttcgccagc agacccgccg tcaaatcgcc gaagtttccg cttggtaccg
    10921 aaacaaccag ctggttgcgc gcctcctgcg gcagctgcgc aacagcttca aagtagtagc
    10981 aaatctgcgc cagcaaacgg ctgatgttaa tcgagttagc tgagtttaac cccagcgcca
    11041 ctttcagttc ttcatcatca aacgcctgct tcaccagcgc ctgacaggca tcgaaatcgc
    11101 cgtcgatggc aacagtttcg atattgccgc ccaatgtaca gaacagtttt tcttgcagtg
    11161 gactgatttt gcctcgtgga tagaggataa ccactttcac attcggcaaa ccgtagaaag
    11221 catgagccac tgccgctccg gtatcaccgg aggtcgcggt cagaatggtc actggcttat
    11281 cacccgcaat atgggtcagc atttgtgcca taaagcgacc gccgaaatct ttaaatgcca
    11341 gcgttggccc gtggaacaat tccagacaac cgacatcgct ttcaacattg gcgaccggag
    11401 ccgggaaggc aaacgccgcg cgcacgcgct cttccaggat ttcctgcggg atttcatcac
    11461 caataaacgc cgagaggatc ttcgcactgc gggtgacaaa atccagcttc agcatctcat
    11521 caatttcagt caggctgaat tccggcaggt catgcggaaa aaacagcccc tgatttttgc
    11581 ccaacccctg ggttacggct tgcgcaaagc tgacctgctc gttgtgatct ttcagattgt
    11641 agagtttcat ttagttttcc agtactcgtg cgcccgccgt atccagccgg caaatatgaa
    11701 caaaaccttc ctgattttgc aggtagttct tacccaacca gtcggcaacg cgctgggcgg
    11761 tatccggctt gtcacacaga gcgaacaagg tcgggccgga gccggagata ccgctcgcta
    11821 ccgcgccgat ttccgcgacc gcctgccgcg cctgccggaa gcctggcagt aatcgttcac
    11881 ggtagggttc agcgataaca tctttcatca gcttcgcggc aagctcaggc tgacgggaat
    11941 agcaggcgtg aatgaagcct gccagatgtc gcccgtgcgc aatgcaatcc tggcggcgat
    12001 actgcgccgg taaaatagcc cgggcttctg ccgtcgagac tttaatcccc ggatacgcca
    12061 gcacccacag ccactcatca aacccaggca cttgctggct gatgatgtcg ttttcttcga
    12121 tcatcaactg cataccacct agaaaacacg gtgccacgtt gtcgtaatga atgctgccgg
    12181 agatacgtcc ttccagctcg cccatcaaag ccagcaaacg agtgtcatta agcggcttgc
    12241 cgcagtgttc attcatcgcc atcagcgccg cgaccaccga acaggcgctg gagcctaagc
    12301 ccgaaccgat cggcatattc ttttccagag tcatcgccac tggaatttgc ttgccaagct
    12361 cctggcaaaa acgctcccag cactgataaa cgatattttc ccgtggttct gacggcagct
    12421 tatcggcaaa gcgcccgagg ttgttgagac tgaatatctc tgccgcctca accgtaacta
    12481 catctccgag caatgcacca tcaacgggtg tcaccgccgc cccgagcaca tcaaacccga
    12541 cgctcatatt ggcactggaa gccggggcat aaactttaac catgtcagac tcctaacttc
    12601 catgagaggg tacgcagcag atcggcaaag acaccagcag cggtaacgtc attgcccgca
    12661 ccatatccgc gcagcaccaa cggcagcggc tgataatagt ggctatagaa ggccagggcg
    12721 ttttcgccat ttttcacttt gaacagcgga tcattaccat ccacttcggc aatcttcacg
    12781 cgacagacgc catcttcatc aatattgcca acatagcgca aaacttttcc ttcatcacgg
    12841 gccttcgcca cgcgcgcggc aaagcgatcg tcgagctgtg acagattcgc cataaaagcg
    12901 gcaacatcac cctcggcgtt aaactctgcg ggcagcacag gttcaatttc aatatccgcc
    12961 agctccagtt cacgtcccgt ttcacgggcg agaatcaata gtttacgcgc cacatccata
    13021 ccagaaagat catctcgcgg atccggttcg gtataaccca tttcccgtgc cagcgtggtc
    13081 gcctcggaga aactcatgcc ttcgtctaac ttgccgaaga tataagaaag cgatcctgaa
    13141 agaatgccgg agaacttcat caattcatca ccagcattga gcagattttg caggttttca
    13201 ataaccggta atccagcccc aacgttggtg tcatagagga atttccgccg cgatttttcc
    13261 gccgcatgac gcaacagatg gtagtaatcc atcgacgagg tgttggcctt tttgttcggc
    13321 gtgacaacgt ggaaaccttc gcgcaggaag tcggcatatt gatccgccac tgcctggctg
    13381 gaggtgcagt caacaatgac cgggttcagc agatgatatt ctttcacgag gcgaattaag
    13441 cgcccgagat taaacggctc tttggcttgc gccagttctt cctgccagtt ttccagattt
    13501 aggccatgca cattggtgag cagtgccttc gagttggcaa caccgcagac acgtaagtcg
    13561 atatgtttat tcttcagcca gctttgttga cgcttcagtt gctccagcag cgcaccgcca
    13621 acgccaccga cgccaatcac aaacacttcg ataacctgat cggtattgaa cagcatctga
    13681 tgagtaacgc gcacgccagt ggtcgcatca tcgttattta ccacgacaga gattgagcgt
    13741 tcagaagatc cctgagcaat agcgacaatg ttgatattgg cgcgggccag cgcggcaaag
    13801 aatttcgccg agatcccacg caaggtacgc ataccatcac ctaccaccga gataatggcc
    13861 agccgttccg tcaccgccag cggctccagt aagccttctt tcagttccag gtagaactct
    13921 tcctgcattg cccgttcagc ccgcacacag tcgctttgcg gaacgcagaa actgatactg
    13981 tattcggaag atgattgcgt aatcagcacc acggaaatac gggcgcgtga catcgcggca
    14041 aagacgcgcg ccgccatgcc gaccattcct ttcatccccg ggccggaaac gctgaacatt
    14101 gccatgttat tcagattgga aatgcccttg accggtaatt cgtcttcatc acgactggca
    14161 ccaatgagcg tacctggtgc ttgaggattt ccggtatttt taatcaggca agggatctgg
    14221 aactgggcga tgggggtaat ggtgcggggg tgaagaactt tagcgccgaa gtaggaaagc
    14281 tccatcgctt cctggtagga catcgacttc aacaacctcg catcgggcac ctgacgcggg
    14341 tcgcaggtat agaccccgtc aacgtccgtc caaatctcgc aacaatcggc gcgtaaacag
    14401 gcagccagca ccgccgcgga gtagtcggaa ccgttgcgtc caagtaccac cagttcgcct
    14461 ttttcattac cggcggtgaa gcctgccatc agcaccatgt gatcagccgg aatacgactt
    14521 gccgcaatac ggcgggtgga ctcagcaata tcgacggtag attcgaggta atgccccact
    14581 gccagtagtt tttcgaccgg atcgataacg gtaacgttgt gaccacgcgc ttctaacacg
    14641 ccggccataa tggcgatcga cattttctcg ccacggcaaa tcagcgcagc gttaatgcta
    14701 tccgggcact gccctaacaa actaatgcca tgcaggacat gttttatttg ggcaaattcc
    14761 tggtcgacga aagttttcaa ttgcgccagc gggaatcccg gctgggcggc ggcgagtccc
    14821 gtcaaaagtt cggcaaaaat acgttcggca tcgctgatat tgggtaaagc atcctggccg
    14881 ctaatggttt tttcaatcat cgccaccagg tggttggtga ttttggcggg ggcagagagg
    14941 acggtggcca cctgcccctg cctggcattg ctttccagaa tatcggcaac ccgcagaaaa
    15001 cgttctgcat ttgccactga tgtaccgccg aacttcaaca ctcgcatggt tgttacctcg
    15061 ttacctttgg tcgaaaaaaa aagcccgcac tgtcaggtgc gggctttttt ctgtgtttcc
    15121 tgtacgcgtc agcccgcacc gttacctgtg gtaatggtga tggtggtggt aatggtggtg
    15181 ctaatgcgtt tcatggatgt tgtgtactct gtaattttta tctgtctgtg cgctatgcct
    15241 atattggtta aagtatttag tgacctaagt caataaaatt ttaatttact cacggcaggt
    15301 aaccagttca gaagctgctg tcagagactc tttttttaat ccacacagag acatattgcc
    15361 cattgcagtc agaatgaaaa gctgaaaaat acttactaag gcgtttttta tttggtgata
    15421 tttttttcaa tatcatgcag caaacggtgc aacattgccg tgtctcgttg ctctaaaagc
    15481 cccaggcgtt gctgtaacca gtcgaccagt tttatgtcat ctgccactgc cagagtcgtc
    15541 agcaatgcca tgactcgttc gcgtaaagct tgcagttgat gttggtctgc cgttgtgtca
    15601 cttttcgtcg gttgttgtat taatgttgct aattgatagc aatagaccat cactgcctgc
    15661 cccagattga gcgaaggata atccgccacc atcggcacac cagtaagaac gtcagccaac
    15721 gctaactctt cgttagtcaa cccggaatct tcgcgaccaa acaccagcgc ggcatggctc
    15781 atccatgaag atttttcctc taacagcggc accagttcaa ctggcgtggc gtagtaatga
    15841 tatttcgccc gactgcgcgc agtggtggcg acagtgaaat cgacatcgtg taacgattca
    15901 accagtgtcg ggaaaacttt aatattatca ataatatcac cagatccatg tgcgacccag
    15961 cgagtggctg gctccagatg tgcctgacta tcgacaatcc gcagttcgct aaaccccatc
    16021 gttttcattg cccgcgccgc tgccccaata ttttctgctc tggcgggtgc gaccagaata
    16081 atcgttatac gcatattgcc actcttcttg accaaatgac cgcgaacagg gtgatcactg
    16141 tcaacttatt acgcggtgcg aatttacaaa tccttaacgt aagtcgcaga aaaagccctt
    16201 tacttagctt aaaaaaggct aaactatttc ctgactgtac taacggttga attgttaaaa
    16261 aatgctacat atccttctgt ttacttagga taattttata aaaaataaat ctcgacaatt
    16321 ggattcacca cgtttattag ttgtatgatg caactagttg gattattaaa ataatgtgac
    16381 gaaagctagc atttagatac gatgatttca tcaaactgtt aacgtgctac aattgaactt
    16441 gatatatgtc aacgaagcgt agttttattg ggtgtccggc ccctcttagc ctgttatgtt
    16501 gctgttaaaa tggttaggat gacagccgtt tttgacactg tcgggtcctg agggaaagta
    16561 cccacgacca agctaatgat gttgttgacg ttgatggaaa gtgcatcaag aacgcaatta
    16621 cgtactttag tcatgttacg ccgatcatgt taatttgcag catgcatcag gcaggtcagg
    16681 gacttttgta cttcctgttt cgatttagtt ggcaatttag gtagcaaaca tgcagacccc
    16741 gcacattctt atcgttgaag acgagttggt aacacgcaac acgttgaaaa gtattttcga
    16801 agcggaaggc tatgatgttt tcgaagcgac agatggcgcg gaaatgcatc agatcctctc
    16861 tgaatatgac atcaacctgg tgatcatgga tatcaatctg ccgggtaaga acggtcttct
    16921 gttagcgcgt gaactgcgcg agcaggcgaa tgttgcgttg atgttcctga ctggccgtga
    16981 caacgaagtc gataaaattc tcggcctcga aatcggtgca gatgactaca tcaccaaacc
    17041 gttcaacccg cgtgaactga cgattcgtgc acgcaacctg ctgtcccgta ccatgaatct
    17101 gggtactgtc agcgaagaac gtcgtagcgt tgaaagctac aagttcaatg gttgggaact
    17161 ggacatcaac agccgttcgt tgatcggccc tgatggcgag cagtacaagc tgccgcgcag
    17221 cgagttccgc gccatgcttc acttctgtga aaacccaggc aaaattcagt cccgtgctga
    17281 actgctgaag aaaatgaccg gccgtgagct gaaaccacac gaccgtactg tagacgtgac
    17341 gatccgccgt attcgtaaac atttcgaatc tacgccggat acgccggaaa tcatcgccac
    17401 catccacggt gaaggttatc gcttctgcgg tgatctggaa gattaatcgg cgttaccacc
    17461 gtcaaaaaaa atggcgcttt ttagcgccgt ttttattttt caaccttatt tccagatacg
    17521 taattgatcg tccattgtaa cttctttact ggctttcatt ttcggcagtg aaaacgcata
    17581 ccagtcgata ttacgagtca caaacatcat gccggccagc gccaccacca gcacactggt
    17641 tcccaacaac agcgcgctat cggcagagtt gagcagtccc cacatcacac catccagcaa
    17701 caacagcgcg agggtaaaca acatgctgtt gcgccagcct ttcaataccg cctgcaaata
    17761 aataccgttc attaacgccc caatcagact ggcgattatc catgccacgg taaaaccgat
    17821 atgttcagaa agcgccagca agagcaaata aaacatcacc aatgaaagcc ccaccagcaa
    17881 atattgcatt gggtgtaaac gttgcgcggt gagcgtttca aaaacaaaga acgccataaa
    17941 agtcagtgca atcagcagaa tggcgtactt agtcgcccgg tccgttaatt ggtattgatc
    18001 ggctggcgtc gtcactgcga cgctaaacgc ggggaagttt tcccagccgg tatcattgcc
    18061 tgaagcaaaa cgctcaccga gattattagc aaaccagctg ctttgccatt gcgcctgaaa
    18121 acctgactcg ctaacttccc gtttggctgg caaaaaatca cctaaaaaac tgggatgcgg
    18181 ccagttgctg gttaaggtca tttcgctatt acgcccggca ggcaccacag aaagatcgcc
    18241 ggtaccgctt aaattcaggg ccatattcag cttcaggttc tgcttccgcc agtccccttc
    18301 gggtaaaggg atatgcacgc cctgcccgcc ttgctctaac ccggtgccgg gttcaatggt
    18361 cagcgccgtt ccgttaactt caggcgcttt caccacacca ataccacgcg catccccgac
    18421 gctaatcaca ataaagggct tgcctaagat gatatttggc gcgttgagct cgctaagacg
    18481 cgaaacatcg aaatcggctt ttagcgttaa atcactgtgc cagacctgac cggtataaat
    18541 ccctatcttg cgttcttcca cgttctgatt gccatcaacc atcaatgact caggtaacca
    18601 aaaatggata aaacttcgtt tccgctccac ggttttatcc tcttcctgca ccgtataaag
    18661 ctcggtcaca ggaatagcga taagcggccc aacgagtttt tgcggcccgc tagtactttg
    18721 gcgaatcgca tcttccacat cgctacggta atcggcacgt tcgacaatca cttgccgaat
    18781 cagcattatc ggaatcaaca acagcaatac tgcaccaaac aaggtggtca ttttccagaa
    18841 caggggggat ttcaacatag tcttctcctt tgcaatggca gcaggatacg aaggctatgt
    18901 gggaagaatt tgaagctatg tgaagtgacg gtgaagtcga agcgaggcca gcacgccacc
    18961 ttcctgcacg ttgcgcagcg tgacttcgcc gttaaacaaa cgggcgacct cactgacgaa
    19021 cgccaacccc agaccgctgc ttttttgccc atttgcacgc ggcaaagagt aaaagcgttc
    19081 aaaaatacgt gacagcgcgt agtcaggaat accactaccg gtatccagca ccttaagggc
    19141 gacgtgttcc tgatccactt cggcgcttag cgttatgcga ccgctctcgg gggtaaaatc
    19201 gatggcgtta tccagtaaat tccccagcgc ctgctccagt aacgccggtt cagcagcaac
    19261 attaacctca gtgggcataa catgtagagt gatgtttttt tctgccaact gcacggtgcg
    19321 cgcttcgctg acgcggcgaa ataatgccgc cacatcaaca acagtcagaa cgacttcctg
    19381 acgattctcc agtcttgcct ggcgtagtaa cgtttctacc aatgcctgca tacgcgcatt
    19441 ttgcgtcaga atgttgtcgg taaaacgagc caccacttcc ggtggcggac cttcgcgtaa
    19501 aatttccgcc gcgccacgaa tcgccgccag tgggcttttt agctcatggg ttaacgcata
    19561 aacatactgc tcaatatagt ttttcccttc cagcttcacg cgcatacttt ccagcgcctg
    19621 cgcaagctta cgcaactcgc tactgccgag ttcaggaaga ggaacgggct tattgtcagt
    19681 gacggaatcg gcatagcgag tgagccgggc aatggagcgg ttgatccacc aaaccatgcc
    19741 tgcgccaatc accagtgcaa tccccagcaa aatggcgctg gcccataaaa ttcgccgctc
    19801 gctacgctta atgaccggag ccatcgccgc gttcggtttg cctacgctca aaacgccaat
    19861 aagccgcgag ccgtccataa tcggcgcggc aacatacatc accgaacttt cgggatcggc
    19921 aggattttgc aacgtgctgc gcgcaccata ctgaccacgc aacgttagcc agacgtcatt
    19981 ccagcgcgaa taatcctgcc caacggcttt atttgccgaa tcgaacaata ctttaccctg
    20041 cgaatcggtc atatagacat gatattcatt gcgcactttg ttaatgccac cgatattggc
    20101 gcgaaacggg cgatgttgta gctgattaaa cgcctgcgcc agttgcccat gcgttgggtc
    20161 cccagagagc aaatcgggac gcgccagctc cgccagcaac gttgcggtat cgattaacgt
    20221 cccctccgtt gctcttcgca cgcccggttt aacttctttg acaaaaatag ccagtacgaa
    20281 ccaggccgcc accgccacca gtaaaaaata gcccagcagc aaccgcatgc cgatacgcat
    20341 tacaggcccc tcaggctata tcccatgccg cgatgagtat taatcggtga aagatcgggg
    20401 ttgatggcgc gcagcttggc acgcaacgtt ttaatgtggg tatcaatggt gcgatcgtag
    20461 gtgtcctgcg catcttccca cacgctatcc attagttgct ggcgggacca gacgcggcct
    20521 ggcgacttga gtaacgtctt cagcaataaa aactcatacc gcgtcagcgt taatggcgtg
    20581 tcaaaccagc tgatctgcgc cgcgggttca ttcaattcaa aatgaccaat acggatgacg
    20641 ggagacggcg acgagaactt cttcacccga cgcagtaagg tgcgcaccct ggcgcacact
    20701 tcgcggggtg aaaacggttt agccacatag tcgtcagcgc caatttccag cccaagcagg
    20761 cgatcgacct cttcacttcg ggccgtcagg aacagtacag gtaacgccgg atggagcgcc
    20821 agtaactggc ggcataattc aaagccgctg atatcaggca aaccaacatc gagaatcatg
    20881 acgtcgggag cctgctggcg agctttatcc agcaccggca agcctcgctc aaagacctcg
    20941 acggcaaaac cttcctgctg caacatgtag accagcgtgt cggctatccc ttgctcatct
    21001 tccactaacc agaccgtttc ccgttgcata aatcgcctct gttattgccg ccacggcatg
    21061 acaggaaccg cgctaatcgc gtttttcggc gaaccttcta caactttgtc ggagtaagcc
    21121 agataagcga gcgcgttgcg tttggcgtca taaaagcgca cgacctgtaa cgacttaaag
    21181 accagggacg tgcgtttttt gaatactacc tcgccctgag ctttgccgtt tttaatacga
    21241 tccgacagtt caatcggccc gacttgctga caagaaatag ccgcatcgga ggtatcttcc
    21301 gccagaccca atcccccttt aatacccccg gttttcgccc ggctcacata acaggtgaca
    21361 tttttcacat cgggatcgtc aaaggcttcc acaacaattt tgtgatccgg gccgatcatt
    21421 ttaaatacgg tgtcgaccga accaatctct tctgcatgag ccaatggccc cagcattatc
    21481 aggcttaaag acaggatcaa atgcttgtat ttcatattgt taccattttt atctattaca
    21541 cgagcaatta gttcgtcacg gtaaataaca tattgattaa gaacaaaatc tcaatacttt
    21601 tatttccgtc aagacctaaa acatactcta ctaagaaaaa aacactgaat gctaaaacag
    21661 caaaaaatgc tattatccaa ttacctgatg tcaggtgctc gttgttgaaa ggatgaggat
    21721 attttatgga tcaggccggc attattcgcg accttttaat ctggctggaa ggtcatctgg
    21781 atcagcccct gtcgctcgac aatgtagcgg cgaaagcagg ttattccaag tggcacttac
    21841 agagaatgtt taaagatgtc actggccatg ctattggcgc gtatattcgt gctcgtcgtt
    21901 tgtcgaaatc ggcggtcgca ctacgcctga ctgcgcgtcc gattctggac atcgcgctgc
    21961 aataccgctt cgactctcaa cagacattta cccgcgcatt caagaagcag tttgcccaga
    22021 ctcctgcact ttaccgccgt tctcctgaat ggagcgcctt tggtattcgc ccgccgctgc
    22081 gtctgggtga attcactatg ccagagcata aatttgtcac cctggaagat acgccgctga
    22141 ttggtgttac ccagagctac tcctgttcgc tggagcaaat ctctgatttc cgccatgaaa
    22201 tgcgttatca gttctggcac gattttctcg gcaacgcgcc gaccattccg ccggtgctct
    22261 acggcctgaa tgaaacgcgt ccgagtcagg ataaagacga cgaacaagaa gtattctata
    22321 ccaccgcgtt agcccaggat caggcagatg gctatgtact gacggggcat ccggtgatgc
    22381 tgcagggcgg cgaatatgtg atgtttacct atgaaggtct gggaaccggc gtgcaggagt
    22441 ttatcctgac ggtatatgga acatgcatgc caatgcttaa cctgacgcgc cgtaaaggtc
    22501 aggatattga gcgatactac ccggcagaag atgccaaagc aggagatcgc ccaattaatc
    22561 tgcgctgtga actgctgatt ccgatccgtc gttaacgctg caactcatct aatgcagggg
    22621 cgtccagatg cgagatgtcc cctgcggttt caacaaccca gccagacgcc agccacaggc
    22681 tttcctgata atccacgcgc gaaatagaac agttacgcag acgtaagcgg cgctctgccc
    22741 atgctggtaa tccgagaatc gtactcacca ggcatcccag tgcaatacca tgactcacca
    22801 gcagcggtcg gcttccctgc ggtaagtccc ggcaagattc cagtgccgca ttgacgcgat
    22861 cgctgagctc ctgcattgac tcgccttcag gaatacgccc gtcaacggtg ccattgacca
    22921 gctgccgacg ccagttctct tcttcttcgg tcagagaatc gatatgtctt ttttccagca
    22981 cacccatgtt taattcacgc aggcgagaat caaagatgat gtcacagccg caggcctggg
    23041 cgatgatttc cgccgtacgc cgggtgcgtc ctaaatcgct actgatgata tgcgtaatgc
    23101 caagctcttt ggcacgggtt gccacctgca tcgcctgttg ctcacctttg gcggtcagcg
    23161 ggctgtcaga ctggccctga atacgtcgct cggcgttcca ctgcgtttca ccgtggcgga
    23221 ctaggtatac ctgtaacatg ctttttttcc gtatactgct gtaacgttaa ttttctgagt
    23281 aatgctgatt atgcaccaag ttgtctgtgc gaccaccaat cccgctaaaa ttcaggccat
    23341 tctgcaggca tttcacgaga tcttcggcga aggatcctgc catattgcat ccgttgccgt
    23401 cgagagcggt gtaccggaac aaccctttgg cagtgaggaa acgcgcgctg gcgcacgaaa
    23461 tcgggtagca aatgcccgcc gtttacttcc agaggctgat ttttgggtgg cgattgaagc
    23521 tggcatcgat ggtgacagca ctttcagttg ggtggtgatt gaaaacgcca gccagcgcgg
    23581 cgaggcgcgt tcggctactt tgccgttgcc tgcggtgatt ctggaaaaag tgcgtgaagg
    23641 cgaggcgctc ggccccgtga tgtcgcgtta taccggtatt gatgagattg gtcgtaagga
    23701 aggggcgatc ggcgtgttta ccgccgggaa actcacccgc gccagcgtct atcaccaggc
    23761 ggtgatcctg gcgctgagtc cgtttcataa tgccgtgtat caggcattgt aggacggata
    23821 aggcgttcac gccgcatccg gcattcggtg cacgatgcct gatgcgacgc tgccgcgtct
    23881 tatcaggcct acaaaatcaa tcgcttttca gcaacacctc ttccagccac tggcgcagct
    23941 caacgggcgc ggctttcagg ctgttagatc cacgcgtaat cgtcgcgatg cccgcgccga
    24001 gttcattttt taactcacgc tggctcattt cgccgcgcaa cagctcttcg acaatacgca
    24061 cgcgagtccc caacgcttcg cgctcatctg gcgtcagcat caggtttaac aacggtaaat
    24121 ggagatcgtt ttggtaggca ttcttaagca ggtcgacaaa acgtaaccac tcctggtgac
    24181 gctgttctgc catcgctgct gaatagggtg attgttgggc cataatatgt cgccattgtt
    24241 agcgggggaa gcaaaatgcc tcccccggtt gtactcgcta aagagtacga tagcatatca
    24301 taaacgtgcg gatcagtaac gacgtcccca ttccgtggcg ctcatcaacg tcggtttatc
    24361 ccccatgaaa tagcggtagt aagcgtcata agccagcacg ttcttcacat aaccgcgcgt
    24421 ctcggagaac ggaatactct cgacaaatgc cacagcgtcg atacgcccgg cgctgttgcc
    24481 aagccaggtt cgcacccgtc caggtccggc gttataagct gctgaggaga aaatacggtt
    24541 attgccaaac tgctgataaa catattgcag gtaactggtg ccaatgttga tattcgtttc
    24601 cggatccagc aattgcccag ggctgctata accaggaata gagaacatct tcaccgtatg
    24661 ggtcgctgta ccaggcataa tctgcatcag gccgctggcc cctaccggtg atttcacttt
    24721 cggattccag gcgctctcct gacgggcaat cgccatcgca tagctttgcg ggatctcttt
    24781 cccactggtg taacgtttga aaagatcgtt gtaagccagc gggaatcgct cttccagatg
    24841 atcccaaagc ttcccggcga tcgttgcctg aacgctaaga tcccaccatt ggttattgaa
    24901 agcataccga gccagttgag cctgctctgt ttttgacttg ctcttcacca gattggccca
    24961 ctcgctacgc gcggtgttat cgagattcca gtacatcaac tcgcgcacgc gcgccatctc
    25021 cggcccctga gtcagggcgc tgtcaacatt ctgcggcgct ttatcaatct tcagctcata
    25081 ctcttctccg atgcgttgtg ctgcaaccat cgggtagaaa ccacgctgtt gcatgagttg
    25141 atgcaaaatc tctttcgctt cagcttcacg tccgcgttcc agcaataaat ccgcctgcca
    25201 gtaacgccat tcatctttct cttttgcttc catcggcaga cgcgccagcc aggtattcag
    25261 gccgcgacga tcgccggtgc caagtgccat tcgcacacgg cgttcaatca acgacgtgga
    25321 ttgcgagcgc ataatggcgt catcgcgcca tttcgcctgc tcgtcggtga catcgttgcc
    25381 catcaaacgc caggcgacga tatcgcgcag ctcctgaata tgatcttcat taagctgctg
    25441 cgcctgggca agcgacggga tcatcagccg tgcattttca gcatcctgcc gcgccacact
    25501 ggcaaacgcc accgccgcca tttgacgggt aaaatcggtc gctccggttg tacgcgcgaa
    25561 ggtcagtacc gtattagggt tgttcgccag tgaaatgatt gccgaggcga tagtctggta
    25621 atcggcaggc atcggccctg ccagcactgt taccaggcca gtgttacccg ctttcatcgc
    25681 cagacggata cgctctaaat aagccagcgg atcttgttta cctgacgcac gccagacgct
    25741 aaataacttg tcacaggcgt taggctggct cttgccggtt agccacagct ctttcgcccc
    25801 ttgccaggct tcttcactct gcccggtgtt ccatttcgca tagtagtaat tacattgcgc
    25861 ttcggtagtt ccgggctttt ccgggctaaa ggctaacaag ccacgccagt cttcacgccg
    25921 cgccagttca ttgacgaaac gagattgcag cgtgcgagcg ggaggaagcg tggggttagc
    25981 gcgaacaaag ttagtgaccg tcaccgccgg ttgattcatc agatcatcgg tgatctggcg
    26041 gtattccagg tagggataaa gcggataatc cttcagtcca ggcatcattt gttcgaccac
    26101 atccatttgt cgattatccc aggcctgctt gatttgcgcg taacggctac gctgctcatc
    26161 cagtgagtcg gctcgcgcca cgctgctgac cgtcagcaga cagacaccgg cagccaacag
    26221 ccgccaggta acttgtttgg ctttttccac aagcgcatcc tctaagtgta aatacatcaa
    26281 tgcagcgtca tgccgcgtaa tagatttatg ctaaccagtc attgccgttt acgccacgtt
    26341 acggacactt ttttactttt actgcgaagg tgatcgacca actgggatta ggcggggaaa
    26401 aaggctacac ttcgcctttg aaaactcatc atcacgataa acatagaggc gaagtccaac
    26461 gtggctcaat tcgtttatac catgcatcgt gtcggcaaag ttgttccgcc gaaacgtcat
    26521 attttgaaaa acatctctct gagtttcttc cctggggcaa aaattggtgt cctgggtctg
    26581 aacggcgcgg gtaagtctac cctgctgcgc attatggcgg gcattgataa agacatcgaa
    26641 ggtgaagcgc gtccgcagcc agacatcaag attggttacc tgccgcagga accgcagctg
    26701 aacccggaac acaccgtgcg tgagtccatt gaagaagcgg tttctgaagt ggttaacgcc
    26761 ctgaaacgcc tggatgaagt gtatgcgctg tacgccgatc cggatgccga ttttgacaag
    26821 ctggccgctg aacaaggccg tctggaagag atcattcagg ctcacgacgg tcataacctg
    26881 aacgtacagc tggagcgtgc ggcggatgcg ctacgtctgc cggactggga cgcgaaaatc
    26941 gctaacctct ccggtggtga gcgtcgtcgc gtagcgttgt gccgcctgct gctggaaaaa
    27001 ccagacatgc tgctgctcga cgaaccgacc aaccacctgg atgccgaatc cgtggcctgg
    27061 ctggaacgct tcctgcacga cttcgagggc accgtggtgg cgattaccca cgaccgttac
    27121 ttcctcgata acgttgcagg ctggatcctc gaacttgacc gcggtgaagg tattccgtgg
    27181 gaaggcaact actcctcctg gctggagcag aaagatcagc gcctggcgca ggaagcttca
    27241 caagaagcgg cgcgtcgtaa gtcgatcgag aaagagctgg agtgggtacg tcagggaact
    27301 aaaggccgcc agtcgaaagg taaagcacgt ctggcacgct ttgaagagct gaacagcacc
    27361 gaatatcaga aacgtaacga aaccaacgaa ctgtttattc cacctggacc gcgtctgggc
    27421 gataaagtgc tggaagtcag caacctgcgt aaatcctacg gtgatcgcct gctgattgat
    27481 gacctgagct tctcgatccc gaaaggggca atcgtcggga tcatcggtcc gaacggcgcg
    27541 ggtaaatcga ccctgttccg tatgatctct ggtcaggaac agccggacag cggcaccatc
    27601 actttaggtg aaacggtgaa actggcatcg gttgatcagt tccgtgactc aatggataac
    27661 agcaaaaccg tttgggaaga agtttccggc gggctggata ttatgaagat cggcaacacc
    27721 gagatgccaa gccgcgccta cgttggccgc tttaacttta aaggggttga tcagggtaaa
    27781 cgcgttggtg aactttccgg tggtgagcgc ggtcgtctgc atctggcgaa gctgctgcag
    27841 gttggcggca acatgctgct gctcgacgaa ccaaccaacg acctggatat cgaaaccctg
    27901 cgcgcgctgg aaaacgccct gctggagttc ccgggctgtg cgatggttat ctcgcacgac
    27961 cgttggttcc tcgaccgtat cgccacgcac atcctggact accaggatga aggtaaagtt
    28021 gagttcttcg aaggtaactt tactgagtac gaagagtaca agaaacgcac gctgggcgca
    28081 gacgcactgg agccgaagcg tatcaagtac aagcgtattg cgaagtaatg cgtaaaatgc
    28141 cggatgcggc gtgaacgcct tatccggcct acaaaccaag aaatttcaat acgttgtgaa
    28201 tctccaggcc tgataagacg cggtaagcgt cgcatcaggc attgagcacc gaatgccgga
    28261 tacggcgtga acgccttttc cggcctacaa cagccttagt atccgcaatt tcgtagcggg
    28321 tcacccgtgc aggttttttc aaaccttgtt taatctcgac agcctcttcc agaaaggttt
    28381 tcaactcatc aaaaaactta ttttatacct cgcctttgag ccgtttcatc gcggttatct
    28441 ctgctccccc atcatctccc gcaccagctc cacgcagcgc aggaaacggc tgtcataatc
    28501 gtcctcttca acccgcacga attcgatatt gttctcttcc agcatctcca ccagcaagtt
    28561 ctggaactct ttgcgatcca ccgaactgcc gaggctgcgt aaaccatccg ccacccacgg
    28621 cgtgttgttc tccagcagga tcaccagatc gaaacggtat tcatcaatca acgcctgcac
    28681 gaacggatgc tcacgccctt cgtacttttt gcagaacgcc tgggtagtga caaaatcagt
    28741 gtcaataaac gccactttat tggcgtattt cactgcaaaa tcaatgtatt gtgcgtggcc
    28801 cagcgcgatt ttatcgtagt cggaatactg caatgcgatc tcatcaccgc cgaggtgtga
    28861 aaagacataa tcgcgaccat attcccacgc actggtggta ttgaagatat tggcaagttt
    28921 gtttaccagg gtggatttac cgctcgactc gccgccaagg atcgccacgg tacgcacaaa
    28981 gaacggcttc acttccgtag gaatatattc ccagtagcgg aacgggtttt cgcggatctg
    29041 cgcaccgctg atactcataa aggtacgttt cggatcgacc agtaccgtct cgatccccag
    29101 atgttccata tactgtggcg catcggcttc ttccgaggtg tagatcaggt ccggctggat
    29161 ccccttttca gccataaact ttttgatgcc gttgctccac acatcccagc catgcggata
    29221 cggctccatg ccctcttcgt tgaaagcatg aatgcgaata tttttctgat atttaaaagt
    29281 ttgcaataac cagcgcagac gatccggcac cgtgggctgc tgcgacatgg cgctgtcttc
    29341 aaacaacgcg cggtcgcggg tatcgtcaaa acccataatg atatgcagct cgtcaacctg
    29401 gctacaggcg cgctggataa ggtagatatg tccggtatgc agcgggtaga acttaccgaa
    29461 tacgacacca atggttttct tctgccgggg aaattcaagc cccaaaaaac ggtgcaacgc
    29521 ctccagcttt tgcgcgctgg ggcttttaat tttggcattc agtaactggc ttaaataccc
    29581 tttggtcata ccgctggcat cagctacctg ctgtaacgtg cagccctgtt gcttgatggc
    29641 agttttcagg taatcaaatg acgacatatc tccctccgta tctctcatta taagtcgtcg
    29701 aacacgctaa gcgcgtcgga gagtttttta acgccaaaaa tctgcatccc ttccggcgct
    29761 tttttcggca cgttagccgc cggaacaatc gcccggcgaa aaccgtgttt cgccgcttca
    29821 gagattcgct cctgaccgct gggcaccggg cggatctccc ctgccagccc gacttcacca
    29881 aacaccacca gatcctgcgg tagcggtctg tcacgcaggc tggaaaccat cgccagcagt
    29941 aacgctaagt cggcactggt ttcggttacc ttcacaccac cgaccacgtt cacaaataca
    30001 tcctgatcgg ccatttgcag accaccgtga cggtgcaaga cagccagcag gattgccaga
    30061 cggttttgct ccagacctac cgccacgcgg cgcggattcg ccatcatcga gtgatcgacc
    30121 agcgcctgaa tctccaccag caacggacgc gttccttccc acaccaccat cacggagctg
    30181 ccggaggtca cttcatctcc gcgacttaag aaaattgccg aagggttgct gacttcacgc
    30241 agcccctgtt cggtcatcgc gaagacgccc agctcattca ccgcgccgaa gcggttttta
    30301 tggctgcgca aggtgcgaaa acgggagtcg gcatcgccat ccaaaagcac cgaacagtcg
    30361 atacagtgtt ccagcacttt agggcccgcc agcgagccat ctttggttac gtgtccaacc
    30421 atgacaatcg ccacaccgcg cgttttggcg aagcgtgtca aataagccgc cgtttcacgc
    30481 acctgcgcca cgctaccagg cgatgactgt acatccgcca tatgcatcac ctggatggag
    30541 tcaattacca tcagcttcgg ttgctcttct tcagcaatca ggcagatctg ctcgatgctg
    30601 gtttccgaca acatattgag attgtcagtc ggcaggccaa ggcgatgagc gcgcattgcc
    30661 acctgttgca gcgactcttc gccggtgaca tacagcgttt tcatctgctg ggccagtttg
    30721 cacagcgttt gcagcaacag cgtggatttc cccgcgcctg ggttaccgcc aatcagaatg
    30781 gcacttcccg gtaccacgcc gccgcctaat acgcggtcga actctttaaa tccggtggaa
    30841 aaacgcggca gctcttcaag gctgatgtcg gagagtttct ggacttttgc caccccggcg
    30901 ctaccggcat agccactgag acgctcgtta cgcgccaccg ttggcgacgc agcaagacgc
    30961 acctcggtga tggtgttcca ggcatgacag gcactgcact gcccctgcca gcgcggataa
    31021 tcggccccgc attcattaca aacaaaggcg cgttttggag cttttgccac ggtgtacctc
    31081 gttaatgctg tgccgcccgc aggatgacgg gcaggcaatt acttctgatt caggctgcca
    31141 gagaggatgc agaatacccc catcaggtca gcgtgacgga tggtgacttc cgtcttttca
    31201 ttcacttttg gcttggcatg gtaggcaatc cccagccctg ccgctttgat catcggcagg
    31261 tcattggctc catcgccaat cgccacggtc tgcgccagcg ggatttcata ctcctgcgcg
    31321 aggcgggtca gagttttcgc tttgtactgc gcgtcaacga tgtcgccgat cacattgccg
    31381 gtaaatttac cgtccatgat ctccagttca ttggctacca cggcggtcag gcgcagcttg
    31441 tcgcgcaggt attcagcaaa gaaagtaaag ccgccggagg caatcgccac tttccagccc
    31501 agcgtttcca gcttgagcac cagctgcgtt aagcctggca tcagcggcag attttcacgc
    31561 acctgttgca gaatattggc atcagcgcct ttcagcgtcg ccacgcggct gcgcaggctg
    31621 gcggtaaaat cgagttcgcc gcgcatcgcc cgttcggtta cctccgccac catctcgccc
    31681 gttccggcca gtttggcaat ttcatcaata cattcaatct ggatggcggt ggaatccatg
    31741 tccatcacca gcaaacccgg cgtgcgcagg tgcgggattt tccccagcgg cgcgacatcc
    31801 agttgcgctt catgggccag gcgcgtagcg cgcgcggtga gtgaacctgc cagacgaatc
    31861 acctgataat cttccacgca ccaggcggca acaatcacca tcgccgcgcc cagtttgctc
    31921 tggtattggg tcaggcgttg tttatccagc ccacgaccat acagcagcca gccgctacga
    31981 cctgcgtggt aatccagtgg catcacttca tcaccactta atgaaagagg cagacccggc
    32041 cataaagaga catcttcagg caggtcgcac caggtaatgt taggcattaa ggctcctgta
    32101 aaatcgttcg aagcagggaa aataacgcat gaggctacct tgtatccatt gcttctggca
    32161 acattaagtc tcaaattttc aaagggtgga agatggctcg cacaaaactg aaattccggc
    32221 tgcatcgggc agtgattgtc ctgttctgtc ttgccttgtt agtggcgctg atgcagggag
    32281 cgtcatggtt tagtcaaaac caccagcgac aacgtaatcc acagctggaa gaactggccc
    32341 gcaccctggc gcgtcaggta acgctgaacg ttgcaccgct gatgcgtacc gactcaccag
    32401 atgaaaaacg cattcaggcg atcctcgatc agttaacgga tgaaagccgc atcctcgacg
    32461 cgggtgtgta tgacgaacaa ggcgatctta tcgcccgttc aggcgaaagc gtcgaagtgc
    32521 gcgaccggct ggcgctcgac ggtaaaaaag caggcggcta ttttaaccag cagattgtcg
    32581 agccaattgc gggtaaaaac ggaccgctcg gctatctgcg cctgacactc gacacccata
    32641 cgctcgccac cgaagcccaa caggtggata acaccactaa cattttacgc ctgatgttgc
    32701 tgctctcact ggcaatcggc gtagtgctga cccgcacgct gctacagggt aaacgcaccc
    32761 gctggcagca atcgcccttc ctgttaaccg ccagcaaacc ggtgccggaa gaggaagaaa
    32821 gcgagaaaaa agagtgaccc attactacaa gaaaggaaat cgttatgtcc acattacgcc
    32881 tgctcatctc tgactcttac gacccgtggt ttaacctggc ggtggaagag tgtatttttc
    32941 gccaaatgcc cgccacgcag cgcgttctgt ttctctggcg caatgccgac acggtagtga
    33001 ttggtcgcgc gcagaacccg tggaaagagt gtaatacccg gcggatggaa gaagataacg
    33061 tccgcctggc gcggcgcagt agcggtggcg gcgcggtgtt ccacgatctc ggcaatacct
    33121 gctttacctt tatggctggc aagccggagt acgataaaac catctctacg tcgattgtgc
    33181 tcaatgcgct gaacgcgctc ggcgtcagcg ccgaagcgtc cgggcgtaac gatctggtgg
    33241 tgaaaacagt cgaaggcgac cgcaaagtct caggctcggc ctatcgcgaa accaaagatc
    33301 gtggcttcca ccacggcact ttgctgctca atgccgacct tagccgcctg gcaaactatc
    33361 tcaatccgga taaaaagaaa ctggcggcga aaggcattac ctcagtgcgt tcccgcgtga
    33421 ccaacctcac cgagctgctg ccggggatca cccatgagca ggtttgcgag gtcataacca
    33481 aggccttttt cgcccattat ggcgagcgtg tagaagcgga aatcatctcc ccggacaaaa
    33541 cgccagactt gccaaacttc gccgaaacct ttgcccgtca gagtagctgg gaatggaact
    33601 tcggtcaggc tccggcattc tcgcatctgc tggatgaacg ctttagctgg ggcggcgtgg
    33661 aactgcattt cgacgttgaa aaaggccata tcacccgcgc ccaggtgttt accgacagcc
    33721 tcaaccccgc gccgctggaa gccctcgccg ggcgactgca aggctgcctg taccgcgcgg
    33781 atatgctgca acaagagtgc gaagcgctgt tggttgactt cccggaccag gaaaaagagc
    33841 tacgggagtt gtcgacgtgg atagcggggg cggtaaggta actcgctgat taaaatacca
    33901 aaggaaggga atatgatcga tctggaaaac caggagcggg agattatcaa tttaatgtta
    33961 agccagcgta tttcctggct agccgccgtg cgtatcaggc ataaattatc gcttgctgaa
    34021 gtaagtaaaa tgttaggtat ctcgattaat tctctaaaac agatcgaaaa gacggaacgg
    34081 cttagctcaa acatcaaaag caaaatggca gaaatttatg gttgtccacc agagttgctg
    34141 atatgccctt cctggatgac ggctgaacat aaatgaatag
//
LOCUS       DAPHKZ010000042        32384 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.042, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000042 DAPHKZ010000000
VERSION     DAPHKZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32384
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.042"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(65..1825)
                     /locus_tag="RH288_002101"
     CDS             complement(65..1825)
                     /locus_tag="RH288_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HDV4031150.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
                     QSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSD
                     IYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQ
                     TLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAH
                     QSLLKAYEKLQRAKAAFWAK"
     gene            1955..2647
                     /locus_tag="RH288_002102"
     CDS             1955..2647
                     /locus_tag="RH288_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDV4031151.1"
                     /translation="MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
                     VYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHMKAGEKQLCPRCANP
                     EWTKASRAKRVT"
     gene            2846..3934
                     /gene="serC"
                     /locus_tag="RH288_002103"
     CDS             2846..3934
                     /gene="serC"
                     /locus_tag="RH288_002103"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HDV4031152.1"
                     /translation="MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGK
                     EFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYW
                     AASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAID
                     ETPDFGADVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKA
                     NIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELL
                     YGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPLEGVKALTDFMVEFERRHG"
     gene            4005..5288
                     /gene="aroA"
                     /locus_tag="RH288_002104"
     CDS             4005..5288
                     /gene="aroA"
                     /locus_tag="RH288_002104"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDV4031153.1"
                     /translation="MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNL
                     LDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPL
                     AAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGG
                     NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQ
                     HYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRF
                     ADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA"
     gene            5457..6221
                     /gene="ycaL"
                     /locus_tag="RH288_002105"
     CDS             5457..6221
                     /gene="ycaL"
                     /locus_tag="RH288_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706828.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase YcaL"
                     /protein_id="HDV4031154.1"
                     /translation="MKNTKLLLAIATSAALLTGCQNTHGIDTNMAISSGLNAYKAATL
                     SDADAKAIANQGCAEMDSGNQVASKSSKYGKRLAKIAKALGNNINGTPVNYKVYMTSD
                     VNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAIVAARDA
                     ISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQGLVGSF
                     EKLASLDGGRTQSMFDSHPPSTERAQHIRDRIASGK"
     gene            6394..7077
                     /gene="cmk"
                     /locus_tag="RH288_002106"
     CDS             6394..7077
                     /gene="cmk"
                     /locus_tag="RH288_002106"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDV4031155.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSMEQVIEKALQ
                     YARQKLALA"
     gene            7188..8861
                     /gene="rpsA"
                     /locus_tag="RH288_002107"
     CDS             7188..8861
                     /gene="rpsA"
                     /locus_tag="RH288_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDV4031156.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            9021..9305
                     /gene="ihfB"
                     /locus_tag="RH288_002108"
     CDS             9021..9305
                     /gene="ihfB"
                     /locus_tag="RH288_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HDV4031157.1"
                     /translation="MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            9513..11777
                     /locus_tag="RH288_002109"
     CDS             9513..11777
                     /locus_tag="RH288_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415433.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HDV4031158.1"
                     /translation="MKITTVGVCIISGIFPLLILPQLPGTLTLAFLTLFACVLAFIPV
                     KTVRYIALTLLFFVWGILSAKQILWAGETLTGATQDAIVEITATDGMTTHYGQITHLQ
                     GRRIFPASGLVMYGEYLPQAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
                     TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRSGQIFLPGRWIHWQIPLIGGICCAAFYAWLTG
                     MQPPALRTMVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPVAILSQSLWLSAAAV
                     AALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANL
                     LAIPLVTFITVPLILAAMVVHLSGPLILEQGLWFLADRSLALLFWGLKSLPEGWINIA
                     ECWQWLSFSPWFLLVVWRLNAWRTLPAMCVAGGLLMCWPLWQKPRPDEWQLYMLDVGQ
                     GLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHLDHRGGL
                     DSILHIWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGSNDKGNNHSCVVK
                     VDDGTNSILLTGDIEAPAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKV
                     ALASASRYNAWRLPSNKVKHRYQLQGYQWIDTPHQGQTTVNFSAQGWRISSLREQILP
                     RWYHQWFGVPVDNG"
     gene            11814..13562
                     /gene="msbA"
                     /locus_tag="RH288_002110"
     CDS             11814..13562
                     /gene="msbA"
                     /locus_tag="RH288_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HDV4031159.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV
                     IERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQI
                     EEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLL
                     EHRGVYAQLHKMQFGQ"
     gene            13559..14545
                     /gene="lpxK"
                     /locus_tag="RH288_002111"
     CDS             13559..14545
                     /gene="lpxK"
                     /locus_tag="RH288_002111"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HDV4031160.1"
                     /translation="MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTT
                     TAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVE
                     IVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNL
                     RTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALV
                     SAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTLLASGN"
     gene            14582..15814
                     /locus_tag="RH288_002112"
     CDS             14582..15814
                     /locus_tag="RH288_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaQ family DNA glycosylase"
                     /protein_id="HDV4031161.1"
                     /translation="MSLPHLSLADARNLHLAAQGLLNKPRRRASLEDIPATISRMSLL
                     QIDTINIVARSPYLVLFSRLGNYPAQWLDESLARGELMEYWAHEACFMPRSDFRLIRH
                     RMLAPEKMGWKYKDAWMQEHEAEIAQLIQHIHDKGPVRSADFEHPRKGASGWWEWKPH
                     KRHLEGLFTAGKVMVIERRNFQRVYDLTHRVMPDWDDERDLVSQTEAEIIMLDNSARS
                     LGIFREQWLADYYRLKRPALVAWREARAEQQQIIAVHVEKLGNLWLHDDLLPLLERAL
                     AGKLTATHSAVLSPFDPVVWDRKRAEQLFDFSYRLECYTPAPKRQYGYFVLPLLHRGQ
                     LVGRMDAKMHRQTGILEVISLWLQEGIKPTTTLQKGLRQAITDFANWQQATRVTLGCC
                     PQGLFTDCRTGWEIDPVA"
     gene            15866..16048
                     /gene="ycaR"
                     /locus_tag="RH288_002113"
     CDS             15866..16048
                     /gene="ycaR"
                     /locus_tag="RH288_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HDV4031162.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPV
                     LLETEARVLTADESKS"
     gene            16045..16791
                     /gene="kdsB"
                     /locus_tag="RH288_002114"
     CDS             16045..16791
                     /gene="kdsB"
                     /locus_tag="RH288_002114"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HDV4031163.1"
                     /translation="MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEP
                     MIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAQEVPGTGVDTPEDLERVRAEMR"
     gene            16945..17838
                     /locus_tag="RH288_002115"
     CDS             16945..17838
                     /locus_tag="RH288_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HDV4031164.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLM
                     ARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEA
                     PARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLN
                     QFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMV
                     GPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFSRRNFDLASKSLLPWLA"
     gene            complement(17815..18594)
                     /gene="elyC"
                     /locus_tag="RH288_002116"
     CDS             complement(17815..18594)
                     /gene="elyC"
                     /locus_tag="RH288_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HDV4031165.1"
                     /translation="MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFIS
                     IGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLD
                     LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRVGYETLGRIWQWLKGSSGEPRQE"
     gene            18730..19515
                     /gene="cmoM"
                     /locus_tag="RH288_002117"
     CDS             18730..19515
                     /gene="cmoM"
                     /locus_tag="RH288_002117"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HDV4031166.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ
                     KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA
                     QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
                     VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK
                     HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV"
     gene            19512..20834
                     /gene="mukF"
                     /locus_tag="RH288_002118"
     CDS             19512..20834
                     /gene="mukF"
                     /locus_tag="RH288_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HDV4031167.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALR
                     DEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            20815..21519
                     /gene="mukE"
                     /locus_tag="RH288_002119"
     CDS             20815..21519
                     /gene="mukE"
                     /locus_tag="RH288_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HDV4031168.1"
                     /translation="MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEENQPDSGEEE"
     gene            21519..25979
                     /gene="mukB"
                     /locus_tag="RH288_002120"
     CDS             21519..25979
                     /gene="mukB"
                     /locus_tag="RH288_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HDV4031169.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMR
                     HANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAK
                     ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARI
                     ASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHE
                     NDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQ
                     FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSY
                     SDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLESSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDL
                     RSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTDEAPSQAS"
     gene            26240..28087
                     /gene="ldtD"
                     /locus_tag="RH288_002121"
     CDS             26240..28087
                     /gene="ldtD"
                     /locus_tag="RH288_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDV4031170.1"
                     /translation="MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAV
                     SEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARD
                     MQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
                     LHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYA
                     AMHESLLALLCDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGD
                     DTPTDAVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGL
                     GADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNG
                     NQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESH
                     GYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYL
                     HDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNI
                     RQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR"
     gene            28268..28816
                     /locus_tag="RH288_002122"
     CDS             28268..28816
                     /locus_tag="RH288_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HDV4031171.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTR
                     KPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            28843..29490
                     /gene="gloC"
                     /locus_tag="RH288_002123"
     CDS             28843..29490
                     /gene="gloC"
                     /locus_tag="RH288_002123"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase GloC"
                     /protein_id="HDV4031172.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDD
                     SGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEEC
                     QPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
                     SDFPRGDHNQLISSIKDKLLPLGDDVIFIPGHGPLSTLGYERLHNPFLQDEMPVW"
     gene            complement(29712..30902)
                     /gene="aspC"
                     /locus_tag="RH288_002124"
     CDS             complement(29712..30902)
                     /gene="aspC"
                     /locus_tag="RH288_002124"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HDV4031173.1"
                     /translation="MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
                     ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMK
                     AAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(31087..32175)
                     /gene="ompF"
                     /locus_tag="RH288_002125"
     CDS             complement(31087..32175)
                     /gene="ompF"
                     /locus_tag="RH288_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HDV4031174.1"
                     /translation="MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHY
                     FSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNK
                     TRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
                     YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADR
                     TNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKT
                     QDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVD
                     YIINQIDSDNKLGVGSDDTVAVGIVYQF"
BASE COUNT         7886 a         7871 c         8711 g         7916 t
ORIGIN      
        1 aaaaaacgcc ccgtaatata actcagacta atcattaagc ctacattgcg taggctattt
       61 gattttattt tgcccagaat gctgctttgg cgcgctgcag cttttcgtag gccttcaaca
      121 acgactgatg tgcagcaaac gcgtgcagat cgctatctac cggttgcagg ccgtaaaacg
      181 ccgcttcgcc gctcattgcc gcactggcgg cttctacggc atctgcgccg tacatgcgaa
      241 caaacgcatt cagatattgc agcggctggc gatcttcttc ctgtgccagt aataacaacg
      301 tttgcaggca gcgataatag ttggcgcgtt ccggactaaa tactgatgag ttaaactcca
      361 tcgtccattc ggtccagacc agagcctgtt ccagatcgcc accagccagc gccagcatgg
      421 cttttaattc accgatacgc agggtgtacc aaccgttatc cgacccggtc gccagaccca
      481 acagctcacg cacgcgggta aagtcatcaa aaccttcttc atccagttgc tcgatgaggt
      541 tcaggtaatc ttctttttcc cactcgctgc ctggtagcga aagaatcgtt tcacgtaaat
      601 ggctgcccat actgttattc gcgagccaca gatcttcagc cggataaata tcggacatgc
      661 caggcacgat aatacggcaa gcataaacgc ccagatgctc gtaatcggca atataaactt
      721 ctttatcttc tttgttgaag atagccatca gtgtggcgaa ctcttcttcc gtggtgccgg
      781 agaaattcca gtccacaaac ggataatcgg catcctgctt gaacaggtcc caggagatta
      841 aaccgctgga atcgataaag tgcgtttcga ggttggtatg ttcagcgact tcttcatcat
      901 cgaaggttgg cggagtaaac acatccaaat ctttcaggcc acgaccttgc agcagctcgg
      961 tcacggtacg ttccagtgct acgccaaaat caggatgcgc accgaaagag gcaaagcagg
     1021 taccgttagc aggattgaac agtaccacgc aaatcaccgg atactggccg ccaagcgaac
     1081 cgtcataagc gaagattggg aaaccctccg cttccagcgt ttcgatggct tcaactactg
     1141 ctgggtaacg cgccagcacg tctgccggga tctctggcag gctgatgctt tcagcaataa
     1201 tgcggttttt cacgtagcgt tcgaaaactt cagacaatcc ctgaacgcgt gcttcgttgc
     1261 gggtattacc tgcggacata ccgttggaga cgtacaggtt accaatgata ttcatcggaa
     1321 tataaacggt ctgattgtcg gactgacgcg taaacggcag gccgcaaata ccacgatctt
     1381 cgttaccgga ttgtaggtca atcagcatgc tgccggtcag ttcattctcc ggatcataaa
     1441 acgcgcgcag acggtcatcg agcagccctt ctggcacatc gtcattttcg gtcagtggga
     1501 accatttttc gttgggataa tgcacgaacg gaccgttggc gatggtttcg cccagccaga
     1561 agtccgcaaa aaagtagttg gttgagagac gctcgaaata ttcaccgagt gcagaagcca
     1621 gcgccgcttt cttggttgcg cctttaccgt tggtaaaaca cagtgcgcac tctttgtcgc
     1681 gaatatgtac agaccagacg ttaggcacgg gattcagcca ggaggcctct tcaatctgaa
     1741 agccgaggtc tgaaagtttt tgctggaagc gagcgatgga atcttccaga gcggcatctt
     1801 tgccggggat aaatgtttgc gtcatgaaaa tcactttagt cgtacggaaa gcgcgcaata
     1861 atacgggttt tatctcaaag gcgctatcac cgccgccatg ccgatgaact gttgactatg
     1921 cttttagcgg ataaaccacg ttaagagcat aaaaatgaag gcgttcgatc tccaccgtat
     1981 ggcatttgat aaagtgcctt ttgatttcct tggcgaagtt gcactacgta gtctttatac
     2041 ctttgtactg gtctttttgt tcctcaaaat gaccggaaga cgcggtgtgc ggcagatgtc
     2101 gctgtttgaa gttttaatca ttctgacgct gggatcagcg gcgggagatg tggcgtttta
     2161 tgatgatgtg ccgatggtcc cggtacttat cgtctttatt actctggcgt tgttataccg
     2221 cctggtaatg tggttgatgg cgcacagtga aaaactggaa gatcttctgg aaggcaagcc
     2281 agttgtcatt attgaagatg gcgagctggc ctggtcgaaa ctcaataact ccaacatgac
     2341 ggaatttgag ttctttatgg agctacgatt gcgtggcgtg gagcagctgg ggcaggtacg
     2401 tctggcgatt ctcgaaacca acgggcaaat cagtgtctat ttctttgaag atgacaaggt
     2461 gaaaccgggt ttacttattt tacccagtga ttgtacgcag cgttacaaag tggtgccgga
     2521 gtcggcggac tatgcctgta ttcgttgtag tgaaatcatt catatgaaag cgggggaaaa
     2581 acaattatgt ccgcgctgtg caaatccaga atggacgaag gcaagtcggg caaaacgggt
     2641 gacctgacag taaaaacatc ggctttttgc taataatccg agagattctt ttgtgtgatg
     2701 caagccacat ttttgccctc aacggtttta ctcattgcga tgtgtgtcac tgaatgataa
     2761 aaccgatagc cacaggaata atgtattacc tgtggtcgca atcgattgac cgcgggttaa
     2821 tagcaacgca acgtggtgag gggaaatggc tcaaatcttc aattttagtt ctggtccggc
     2881 aatgctaccg gcagaggtgc ttaaacaggc tcaacaggaa ctgcgcgact ggaacggtct
     2941 tggtacgtcg gtgatggaag tgagtcaccg tggcaaagag ttcattcagg ttgcagagga
     3001 agccgagaag gattttcgcg atcttcttaa tgtcccctcc aactacaagg tattattctg
     3061 ccatggcggt ggtcgcggtc agtttgctgc ggtaccgctg aatattctcg gtgataaaac
     3121 caccgcagat tatgttgatg ccggttactg ggcggcaagt gccattaaag aagcgaaaaa
     3181 atactgcacg cctaatgtct ttgacgccaa agtgactgtt gatggtctgc gcgcggttaa
     3241 gccaatgcgt gaatggcaac tctctgataa tgctgcttat atgcattatt gcccgaatga
     3301 aaccatcgat ggtatcgcca tcgacgaaac gccagacttc ggcgcagatg tggtggtcgc
     3361 cgctgacttc tcttcaacca ttctttcccg tccgattgac gtcagccgtt atggtgtaat
     3421 ttacgctggc gcgcagaaaa atatcggccc ggctggcctg acaatcgtca tcgttcgtga
     3481 agatttgctg ggcaaagcga atatcgcgtg tccgtcgatt ctggattatt ccatcctcaa
     3541 cgataacggc tccatgttta acacgccgcc gacatttgcc tggtatctat ctggtctggt
     3601 ctttaaatgg ctgaaagcga acggcggtgt agctgaaatg gataaaatca atcagcaaaa
     3661 agcagaactg ctatatgggg tgattgataa cagcgatttc taccgcaatg acgtggcgaa
     3721 agctaaccgt tcgcggatga acgtgccgtt ccagttggcg gacagtgcgc ttgacaaatt
     3781 gttccttgaa gagtcttttg ctgctggcct tcatgcactg aaaggtcacc gtgtggtcgg
     3841 cggaatgcgc gcttctattt ataacgccat gccgctggaa ggcgttaaag cgctgacaga
     3901 cttcatggtt gagttcgaac gccgtcacgg ttaatgccaa aattttgctt aatccccaca
     3961 gccagcctgt ggggttttta tttctgttgt agagagttga gttcatggaa tccctgacgt
     4021 tacaacccat cgctcgtgtc gatggcacta ttaatctgcc cggttccaag agcgtttcta
     4081 accgcgcttt attgctggcg gcattagcac acggcaaaac agtattaacc aatctgctgg
     4141 atagcgatga cgtgcgccat atgctgaatg cattaacagc gttaggggta agctatacgc
     4201 tttcagccga tcgtacgcgt tgcgaaatta tcggtaacgg cggtccatta cacgcagaag
     4261 gtgccctgga gttgttcctc ggtaacgccg gaacggcaat gcgtccgctg gcggcagctc
     4321 tttgtctggg tagcaatgat attgtgctga ccggtgagcc gcgtatgaaa gaacgcccga
     4381 ttggtcatct ggtggatgcg ctgcgcctgg gcggggcgaa gatcacttac ctggaacaag
     4441 aaaattatcc gccgttgcgt ttacagggcg gctttactgg cggcaacgtt gacgttgatg
     4501 gctccgtttc cagccaattc ctcaccgcac tgttaatgac tgcgcctctt gcgccggaag
     4561 atacggtgat tcgtattaaa ggcgatctgg tttctaaacc ttatatcgac atcacactca
     4621 atctgatgaa gacgtttggt gttgaaattg aaaatcagca ctatcaacaa tttgtcgtaa
     4681 aaggcgggca gtcttatcag tctccgggta cttatttggt cgaaggcgat gcatcttcgg
     4741 cttcttactt tctggcagca gcagcaatca aaggcggcac tgtaaaagtg accggtattg
     4801 gacgtaacag tatgcagggt gatattcgct ttgctgatgt gctggaaaaa atgggcgcga
     4861 ccatttgctg gggcgatgat tatatttcct gcacgcgtgg tgaactgaac gctattgata
     4921 tggatatgaa ccatattcct gatgcggcga tgaccattgc cacggcggcg ttatttgcaa
     4981 aaggcaccac cacgctgcgc aatatctata actggcgtgt taaagagacc gatcgcctgt
     5041 ttgcgatggc aacagaactg cgtaaagtcg gcgcggaagt ggaagagggg cacgattaca
     5101 ttcgtatcac tcctccggaa aaactgaact ttgccgagat cgcgacatac aatgatcacc
     5161 ggatggcgat gtgtttctcg ctggtggcgt tgtcagatac accagtgacg attcttgatc
     5221 ccaaatgcac ggccaaaaca tttccggatt atttcgagca gctggcgcgg attagccagg
     5281 cagcctgaat gaacaacggg caataaatag ccaaatcttt ctttatcaaa acgtcggcac
     5341 attgtcggcg ttttttttcg gaccttgtga gtcattttga ttaatggtag cgtcgcttgt
     5401 caatgtaagt tgttgataca taatatttat atatgattaa tcaacggatg attcacatga
     5461 agaatactaa attactgctg gcgattgcga cctctgcagc attactgaca gggtgtcaaa
     5521 atacccacgg tattgatacc aatatggcta tcagctccgg tttaaatgcc tataaagcag
     5581 caacattaag cgatgccgat gcaaaagcga ttgccaatca gggctgtgcc gaaatggaca
     5641 gcggcaatca agtcgcaagt aaatccagca agtacggtaa acgtctggca aaaatcgcca
     5701 aagcattggg taacaatatt aatggcacgc cggtcaacta taaggtttat atgaccagcg
     5761 acgtcaacgc atgggcgatg gcgaacggct gtgttcgtgt ctacagtggc ctgatggaca
     5821 tgatgaatga caacgaaatt gaaggcgttc tgggccatga actgggccac gtcgcgttgg
     5881 gtcactcgct ggctgaaatg aaagcttctt atgcgatcgt tgccgcacgc gatgccattt
     5941 cagctaccag cggtgtggct tcccagcttt cccgctcaca attaggtgat atcgcagaag
     6001 gcgctatcaa tgctaaatac tcccgtgata aagagtccga agcagatgat ttctcctttg
     6061 atctgttgaa gaaacgtggc atcagcaccc aggggctggt tggcagcttt gaaaaactgg
     6121 ctagcctgga tggcggtcgc acccagtcca tgtttgactc tcacccacca tcaacagagc
     6181 gtgcgcaaca catccgtgat cgtatcgcct ctggtaagta aatcattgtc atctttcggg
     6241 ctggtcttct gccagcccgc tataattgcg caataaatcc ccatctgaat acagacaaaa
     6301 ctggtttttg cacacaacgt taacgatttg tggcgtcggc gcgtataatg cgcgcggtta
     6361 tgttaacggt acgcctgttt taaggagata aagatgacgg caattgcccc ggttattacc
     6421 attgatggcc caagcggtgc agggaaaggc accttgtgta aggctatggc ggaagcgttg
     6481 caatggcatc tgctggactc gggtgcaatt tatcgcgtac tggcattggc ggcattacat
     6541 caccatgttg atgttgcgtc ggaagatgcg ctggtaccgc tggcatccca tctggatgta
     6601 cgttttgtgt cgaccaatgg caatctggaa gtgatcctcg aaggggaaga tgtcagcggc
     6661 gaaattcgta ctcaggaagt ggcgaatgca gcttcacaag tcgcggcatt cccacgcgtt
     6721 cgtgaagcat tattgcgtcg ccaacgcgcg tttcgcgaat taccaggtct gattgccgat
     6781 ggccgcgaca tgggaacggt ggtattccct gatgcaccag tgaaaatttt ccttgacgcc
     6841 tcctcggaag aacgtgcgca tcgccgcatg ctacagttgc aggagaaggg ctttagtgtt
     6901 aactttgagc gccttttggc cgagatcaaa gaacgcgacg accgcgatcg taaccgagcg
     6961 gtagcgccac tggttccggc agccgatgct ttagtgttgg attccaccac cttaagcatg
     7021 gagcaagtga ttgaaaaagc gctacaatac gcgcgccaga aattggctct cgcataagcg
     7081 accgaatttg cagtaccccc gttgcaatgg aatgacagcg ggtatgttaa acaaccccat
     7141 ccggcatgga gccaggtgga cgttaaatat aaacctgaag attaaacatg actgaatctt
     7201 ttgctcaact ctttgaagag tccttaaaag aaatcgaaac ccgcccgggt tctatcgttc
     7261 gtggcgttgt tgttgctatc gacaaagacg tagtactggt tgacgctggt ctgaaatctg
     7321 agtccgccat cccggctgag cagttcaaaa acgcccaggg cgagctggaa atccaggtag
     7381 gtgacgaagt tgacgttgct ctggacgcag tagaagacgg cttcggtgaa actctgctgt
     7441 cccgtgagaa agctaaacgt cacgaagcct ggatcacgct ggaaaaagct tacgaagatg
     7501 ctgaaactgt taccggtgtt atcaacggca aagttaaggg cggcttcact gttgagctga
     7561 acggtattcg tgcgttcctg ccaggttctc tggtagacgt tcgtccggtg cgtgacactc
     7621 tgcacctgga aggcaaagag cttgaattta aagtaatcaa gctggatcag aagcgcaaca
     7681 acgttgttgt ttctcgtcgt gccgttatcg aatccgaaaa cagcgcagag cgcgatcagc
     7741 tgctggaaaa cctgcaggaa ggcatggaag ttaaaggtat cgttaagaac ctcactgact
     7801 acggtgcatt cgttgatctg ggcggcgttg acggcctgct gcacatcact gacatggcct
     7861 ggaaacgcgt taagcatccg agcgaaatcg tcaacgtggg cgacgaaatc actgttaaag
     7921 tgctgaagtt cgaccgcgaa cgtacccgtg tatccctggg cctgaaacag ctgggcgaag
     7981 atccgtgggt agctatcgct aaacgttatc cggaaggtac caaactgact ggtcgcgtga
     8041 ccaacctgac cgactacggc tgcttcgttg aaatcgaaga aggcgttgaa ggcctggtac
     8101 acgtttccga aatggattgg accaacaaaa acatccaccc gtccaaagtt gttaacgttg
     8161 gcgatgtagt ggaagttatg gttctggata tcgacgaaga acgtcgtcgt atctccctgg
     8221 gtctgaaaca gtgcaaagct aacccgtggc agcagttcgc ggaaacccac aacaagggcg
     8281 accgtgttga aggtaaaatc aagtctatca ctgacttcgg tatcttcatc ggcctggacg
     8341 gcggcatcga cggcctggtt cacctgtctg acatctcctg gaacgttgca ggcgaagaag
     8401 cagttcgtga atacaaaaaa ggcgacgaaa tcgctgcagt tgttctgcag gttgacgcag
     8461 aacgtgaacg tatctccctg ggcgttaaac agctcgcaga agatccgttc aacaactggg
     8521 ttgctctgaa caagaaaggc gctatcgtaa ccggtaaagt aactgcagtt gacgctaaag
     8581 gcgcaaccgt agaactggct gacggcgttg aaggttacct gcgtgcttct gaagcatccc
     8641 gtgaccgcgt tgaagacgct accctggttc tgagcgttgg cgacgaagtt gaagctaaat
     8701 tcaccggcgt tgatcgtaaa aaccgcgcaa tcagcctgtc tgttcgtgcg aaagacgaag
     8761 ctgacgagaa agatgcaatc gcaactgtta acaaacagga agatgcaaac ttctccaaca
     8821 acgcaatggc tgaagctttc aaagcagcta aaggcgagta attctctgac tcttcgggat
     8881 ttttattccg aagtttgttg agtttacttg acagattgca ggtttcgtcc tgtaatcaag
     8941 cactaagggc ggctacggcc gcccttaatc aatgcagcaa cagcagccgc ttaatttgcc
     9001 tttaaggaac cggaggaatc atgaccaagt cagaattgat agaaagactt gccacccagc
     9061 aatcgcacat tcccgccaag acggttgaag atgcagtaaa agagatgctg gagcatatgg
     9121 cctcgactct tgcgcagggc gagcgtattg aaatccgcgg tttcggcagt ttctctttgc
     9181 actaccgcgc accacgtacc ggacgtaatc cgaagactgg cgataaagta gaactggaag
     9241 gaaaatacgt tcctcacttt aaacctggta aagaactgcg cgatcgcgcc aatatttacg
     9301 gttaagtttt ttactcaaac ttgaacgaga gaaaagcacc tgtcgggtgc ttttttcatt
     9361 tctctaatct ggaactggaa gctgcctcgc agagttttga acagttttca ccctttcgtt
     9421 aaattcttct gaatatgcct cggggaacgc aaaattccca ccagacaacc gctcaacaaa
     9481 gttgcacact ttccataaac agggaggggt gcatgaaaat aacgacagtc ggtgtatgca
     9541 taattagcgg aatttttccg ttgctgattt tgccccaatt gcctgggaca ttaacccttg
     9601 cgtttctgac tctcttcgcc tgcgtactgg catttatccc tgttaaaacc gtccgttata
     9661 tcgcgctgac gttgctgttt ttcgtttggg gcatattatc agcaaagcaa attttgtggg
     9721 caggagaaac cttaactggc gcgacgcagg atgcaattgt tgagatcact gcaactgacg
     9781 gcatgaccac tcattacggt caaattactc atctacaagg tcgacgtata ttccctgcgt
     9841 caggtctcgt gatgtatggc gaatatcttc cgcaagcggt ttgtgctgga caacaatggt
     9901 caatgaaact caaagttcgt gcagttcatg gccaacttaa tgatggcggc tttgatagcc
     9961 agcgttatgc cattgcccag catcagccgc tcaccggccg ttttctgcag gcaagtgtca
    10021 ttgaaccgaa ttgtagcctg cgtgcacagt atctggcgtc actacaaaca acgctgcaac
    10081 cctatccgtg gaatgcggtt attcttggtt taggtatggg ggaacggtta tccgtcccca
    10141 aagaaatcaa aaatatcatg cgcgatactg gaacggcgca tttaatggcg atatcgggat
    10201 tgcacatcgc ttttgcggcg ttgctggctg ccggactcat tcgcagtgga caaatttttc
    10261 tgcctgggcg ctggatccac tggcaaatac cattaattgg cggaatctgc tgtgctgctt
    10321 tttatgcctg gttgacggga atgcaacctc ctgcattgcg taccatggtg gcgcttgcta
    10381 cgtggggaat gcttaagtta agtgggcgac agtggagtgg ctgggatgta tggatatgtt
    10441 gtctggcggc aattttgctg atggatcctg ttgccattct ctcgcaaagt ttatggctct
    10501 ctgccgctgc ggtcgcggca ttgatatttt ggtatcagtg gtttccctgt cctgagtggc
    10561 aactgccgcc ggtattgcgt gcagttgttt ccctcatcca tctgcaactg ggaatcacac
    10621 ttctgcttat gcccgtgcaa atcgtcatat ttcatggcat tagtctgacc tcgtttattg
    10681 caaatctatt agcaattccc ttggtgacat ttatcacggt tccgttgatc ctcgccgcga
    10741 tggttgtgca tttaagcggg ccgttaatcc tggagcaagg gttatggttt cttgccgacc
    10801 ggtctttggc tttacttttc tgggggttaa agagtttgcc ggaagggtgg atcaacattg
    10861 ctgaatgttg gcaatggcta tcattttccc catggttctt actggtggta tggcgattaa
    10921 acgcctggcg aacgttgcca gcaatgtgtg tggctggagg cttgctgatg tgctggccgc
    10981 tgtggcaaaa acctcgacct gacgagtggc agctgtacat gcttgatgtc gggcaagggc
    11041 tggcaatggt gatagccaga aacggcaaag cgattctcta tgacacagga ctggcctggc
    11101 ctgaagggga tagtgggcaa caactgatta tcccctggct ccactggcat aatcttgaac
    11161 cggaaggcgt tattctgagc catgaacatc tggatcaccg gggagggctg gattcaatat
    11221 tgcatatatg gccgatgtta tggatcagaa gtccgttaaa ctgggaacat catcagccct
    11281 gtgtgcgtgg cgaagcgtgg caatggcaag gattgcgttt cagcgcgcac tggcctttac
    11341 aaggtagcaa cgataaagga aataaccatt cctgtgtggt taaggttgat gacgggacga
    11401 atagcattct tctaaccggt gatattgaag ccccagctga acaaaagatg ctaagccgtt
    11461 actggcagca agtgcaggca acattgcttc aggtacctca ccatggcagt aatacctcat
    11521 catcgttgcc attaattcag cgagtgaatg gaaaagtggc actcgcatcg gcatcgcgct
    11581 ataacgcatg gcgactgccc tctaacaaag ttaagcatcg ctatcaactg caaggatatc
    11641 aatggattga tactccacat caaggtcaaa caacggtcaa tttttcagcg caaggctggc
    11701 ggattagcag cctcagggag caaattttac ctcgttggta tcatcagtgg tttggcgtgc
    11761 cagtggataa cgggtagaat atgcggctat ttcaacaaat gctggttttt tgaatgcata
    11821 acgacaaaga tctctctacg tggcagacat tccgccgact gtggccaacc attgcgcctt
    11881 tcaaagcggg tctgatcgtg gcgggcgtag cgttaatcct caacgcagcc agcgatacct
    11941 tcatgttatc gctccttaag ccacttcttg atgatggctt tggtaaaaca gatcgctccg
    12001 tgctggtgtg gatgccgctg gtggtgatcg ggctgatgat tttacgtggt atcaccagct
    12061 atgtctccag ctactgtatc tcctgggtat caggaaaggt ggtaatgacc atgcgtcgcc
    12121 gcctgtttgg tcacatgatg ggaatgccag tttcattctt tgacaaacag tcaacgggta
    12181 cgctgttgtc acgtattacc tacgattccg aacaggttgc ttcttcttct tccggcgcac
    12241 tgattactgt tgtgcgtgaa ggtgcgtcga tcatcggcct gttcatcatg atgttctatt
    12301 acagttggca actgtcgatc attttgattg tgctggcacc gattgtttcg attgcgattc
    12361 gcgttgtatc gaagcgtttt cgcaacatca gtaaaaacat gcagaacacc atggggcagg
    12421 tgaccaccag cgcagaacaa atgctgaagg gccacaaaga agtattgatt ttcggtggtc
    12481 aggaagtgga aacgaaacgc tttgataaag tcagcaaccg aatgcgtctt caggggatga
    12541 aaatggtttc agcctcttcc atctctgatc cgatcattca gctgatcgcc tctttggcgc
    12601 tggcgtttgt tctgtatgcg gcgagcttcc caagtgtcat ggatagcctg actgccggta
    12661 cgattaccgt tgttttctct tcaatgattg cactgatgcg tccgctgaaa tcgctgacca
    12721 acgttaacgc ccagttccag cgcggtatgg cggcttgtca gacgctgttt accattctgg
    12781 acagtgagca ggagaaagat gaaggtaagc gcgtgatcga gcgtgcgact ggcgacgtgg
    12841 aattccgcaa tgtcaccttt acttatccgg gacgtgacgt acctgcattg cgtaacatca
    12901 acctgaaaat tccggcaggg aagacggttg ctctggttgg acgctctggt tcgggtaaat
    12961 caaccatcgc cagcctgatc acgcgttttt acgatattga tgaaggcgaa atcctgatgg
    13021 atggtcacga tctgcgcgag tataccctgg cgtcgttacg taaccaggtt gctctggtgt
    13081 cgcagaatgt ccatctgttt aacgatacgg ttgctaacaa cattgcttac gcacggactg
    13141 aacagtacag ccgtgagcaa attgaagaag cggcgcgtat ggcctacgcc atggacttca
    13201 tcaataagat ggataacggt ctcgatacag tgattggtga aaacggcgtg ctgctctctg
    13261 gcggtcagcg tcagcgtatt gctatcgctc gagccttgtt gcgtgatagc ccgattctga
    13321 ttctggacga agctacctcg gctctggata ccgaatccga acgtgcgatt caggcggcac
    13381 tggatgagtt gcagaaaaac cgtacctctc tggtgattgc ccaccgcttg tctaccattg
    13441 aaaaggcaga cgaaatcgtg gtcgtcgagg atggtgtcat tgtggaacgc ggtacgcata
    13501 acgatttgct tgagcaccgc ggcgtttacg cgcaacttca caaaatgcag tttggccaat
    13561 gatcgaaaaa atctggtctg gtgaatcccc tttgtggcgg ctattgctgc cactctcctg
    13621 gttgtatggc ctggtgagtg gcgcgatccg tctttgctat aaactaaaac tgaagcgcgc
    13681 ctggcgtgcc cccgtaccgg ttgtcgtggt tggtaatctc accgcaggcg gcaacggaaa
    13741 aaccccggtc gttgtctggc tggtggaaca gttgcaacag cgcggtattc gcgtgggggt
    13801 cgtatcgcgg ggatatggtg gtaaggctga atcttatccg ctgttattgt cggcagatac
    13861 cacaacagca caggcgggtg atgaacctgt gttgatttat caacgcactg atgcgcctgt
    13921 tgcggtttct cccgttcgtt ctgatgcggt aaaagccatt ctggcgcaac accctgatgt
    13981 gcagatcatc gtaaccgacg acggtttaca gcattaccgt ctggcgcgtg atgtggaaat
    14041 tgtcgttatt gatggtgtgc gtcgctttgg caatggctgg tggttgccgg cggggccaat
    14101 gcgtgagcga gcggggcgct taaagtcggt tgatgcggta atcgtcaacg gcggtgtccc
    14161 tcgcagcggt gaaatcccca tgcatctgct gccgggtcag gcggtgaatt tacgtaccgg
    14221 tacgcgttgt gacgttgctc agcttgaaca tgtagtggcg atggcgggga ttgggcatcc
    14281 gccgcgcttt tttgccacgc tgaagatgtg tggcgtacaa ccggaaaaat gtgtaccgct
    14341 ggccgatcat cagtctttga accatgcgga tgtcagtgcg ttggtaagcg ccgggcaaac
    14401 gctggtaatg actgaaaaag atgcggtgaa atgccgggcc tttgcagaag aaaattggtg
    14461 gtatttgcct gtagacgcac agctttcagg tgatgaacca gcgaaactgc ttacgcaact
    14521 aaccttgctg gcttctggca actagttacg ccgcggcagc gttcgattga tggagtcatg
    14581 aatgtcgctg ccgcacctct cccttgctga tgcgcgtaat cttcaccttg ccgcacaagg
    14641 cctgttaaac aaaccccgcc gtcgagcgtc gttggaggat attccggcaa cgatctcccg
    14701 catgtccttg ctgcaaatcg ataccatcaa tattgttgcc cgtagtccat atctggtgct
    14761 tttcagtcgt ctgggaaatt atcctgccca gtggctggat gagtctctgg cgcgtggcga
    14821 attaatggaa tactgggcgc atgaagcctg ctttatgccg cgtagcgact ttcgtcttat
    14881 tcgccaccgc atgctggcac ctgaaaaaat gggctggaaa tacaaagacg cctggatgca
    14941 ggaacatgag gcggaaattg cacagttaat tcagcatatt catgataagg ggccggtacg
    15001 ttcagccgat tttgagcatc ctcgtaaagg tgcaagcggc tggtgggaat ggaagccgca
    15061 taaacggcat ctggaaggtt tatttactgc cggaaaggtg atggtgattg aacggcgcaa
    15121 cttccagcgc gtttatgatt taacccaccg tgtcatgcct gactgggatg atgagcgcga
    15181 tctcgtttcg caaacagaag cagaaatcat catgctggat aacagtgcgc gtagcctggg
    15241 aatattccgc gaacagtggc tggcagatta ctatcggctg aaacgtccgg cactggtggc
    15301 gtggcgcgaa gcgagggctg aacagcagca aatcattgct gtgcatgttg aaaaattggg
    15361 caatctttgg ctgcatgatg atttgctgcc gctactcgag cgagcgctgg ccggaaagct
    15421 cactgcaacg cacagcgcgg tactttcgcc ttttgatcct gttgtctggg atcgcaaacg
    15481 cgcagagcag ctttttgatt ttagctaccg gctggagtgc tataccccag cgccgaaacg
    15541 ccagtatggc tattttgttc tgccgttatt acatcgtggg caattagttg ggcgaatgga
    15601 tgccaaaatg catcgccaga caggcatcct tgaagttatc tctctgtggt tacaggaagg
    15661 tattaaacca acgacaacgc tgcaaaaagg gctacgtcag gcgattactg atttcgctaa
    15721 ctggcagcag gcaacgcggg tgacattagg atgctgcccg caaggcctct ttactgattg
    15781 ccgcaccggc tgggaaatag accccgtcgc ataaatgatt atgataagat ttatgcattc
    15841 ataacccgat ccatctggag gaactatgga tcatcgtctg cttgaaatca ttgcctgccc
    15901 ggtttgcaac ggaaaacttt ggtataacca ggaaaaacaa gagcttattt gcaaactgga
    15961 caacctcgct ttcccgctgc gtgatggcat tccagtgttg ctggaaacgg aagcccgcgt
    16021 gctgactgct gatgagagta aatcatgagt tttgtggtca ttattcccgc gcgctacgcg
    16081 tccacgcgtc tgcccggtaa accattggtt gatattaacg gcaaacccat gattgttcat
    16141 gttcttgaac gcgcgcgtga atcaggtgcc gagcgcatca tcgtggcaac cgatcatgag
    16201 gatgttgccc gcgccgttga agccgctggc ggtgaagtat gtatgacgcg cgccgatcat
    16261 cagtcaggaa cagaacgtct ggcggaagtt gtcgaaaaat gcgcattcag cgacgacacg
    16321 gtgatcgtta atgtgcaggg tgatgaaccg atgatccctg cgacaatcat tcgtcaggtt
    16381 gctgataacc tcgctcagcg tcaggtgggt atggcgactc tggcggtgcc aatccacaat
    16441 gcggaagaag cgtttaaccc gaatgcggtg aaagtggttc tcgacgctga agggtatgca
    16501 ctgtacttct ctcgcgccac cattccttgg gatcgtgatc gttttgcaga aggccttgaa
    16561 accgttggcg ataacttcct gcgtcatctt ggtatttatg gctaccgtgc aggctttatc
    16621 cgtcgttacg tcaactggca gccaagtccg ttagaacaca tcgaaatgtt agagcagctt
    16681 cgtgttctgt ggtacggcga aaaaatccat gttgctgttg ctcaggaagt tcctggcaca
    16741 ggtgtggata cccctgaaga tcttgagcgc gttcgcgctg aaatgcgcta atttcacttc
    16801 acgacacttc agccaatttt gggaggagtg tcgtaccgtt acgattttcc tcaatttttc
    16861 ttttcaacaa ttgatctcat tcaggtgaca tcttttatat tggcgctcat tatgaaagca
    16921 gtagctttta tgagggtaat ctgaatggaa cagctgcgtg ccgaattaag ccatttactg
    16981 ggcgaaaaac tcagtcgtat tgagtgcgtc aatgaaaaag cggatacggc gttgtgggct
    17041 ttgtatgaca gccagggaaa cccaatgccg ttaatggcaa gaagctttag tacgcccgga
    17101 aaagcccgac aactggcatg gaaaaccacc atgctggcaa gaagtgggac tgtccgtatg
    17161 ccgactattt atggtgtgat gacgcatgaa gaacaccccg gccccgatgt cctgctactg
    17221 gagcggatgc gtggtgtttc ggtggaggca ccagcccgaa caccagaacg ctgggaacaa
    17281 ctcaaagacc aaatcgttga agccttactg gcctggcacc gtcaggacag tcgcggttgc
    17341 gtcggcgcgg tcgacaatac tcaggaaaat ttctggccct catggtaccg gcaacatgtt
    17401 gaagtgctat ggaccacgct caatcagttc aataacaccg gtctgacgat gcaggataag
    17461 cggatcctgt ttcgcactcg cgaatgtctc ccggcattat ttgaaggctt taacgacaat
    17521 tgtgtgctga ttcacggtaa cttctgttta cgcagcatgt tgaaagattc gcgcagcgat
    17581 cagttactgg cgatggtcgg gccgggacta atgctttggg caccgcgaga atacgaactg
    17641 ttccgactaa tggataattc tctggcggaa gatttgctct ggagttacct gcaacgcgcg
    17701 ccagtggcgg agtcgttcat ctggcggcgt tggttgtatg tgttatggga tgaagttgcg
    17761 caactggtta ataccggacg atttagtcgg cgcaacttcg atctggcatc aaaatcactc
    17821 ttgccgtggc tcgcctgacg aaccttttag ccactgccag atacggccaa gcgtttcata
    17881 gccaacacga tcgctatgca tcaaccagac cggagaaggg attgcccgtt cccacgggtt
    17941 aagcggcgag tcgatggcca actgattcgc cggggctggt agcggattta acccttcctg
    18001 ctgaaaaaag atcatcgccc gcggcagatg tgatgcggag gtcaccagca ggaaaggggc
    18061 gtcaccaatc gcctgtttca ctgctgcagc ttcttcttcg gtatcttttg gcaaatccag
    18121 ggtgataatt tgctcgcgcg gcacgcccag cgattgcgca actctggcac ctacttccgc
    18181 tgtactcacc gtattggttt ttgctacgcc tcccgtgaag atcagttttg atcccggatt
    18241 ttcgcgccat aagcgaatac cttcattcag gcgtggcaga ctgttattga ttaaattaga
    18301 gctcggtgcc cactgcgggt tccaggtata accacctccg agcaccacga tatagtccac
    18361 tttttgcgaa ttattccatg tcggataggt gctttcgatg ggacgcagca ggcggtcggc
    18421 taccggttgc aaactcaata acaagagcgc cagccaccca atgctaataa aaatcttccc
    18481 ggttttttga aaacggctaa accacagcag cgccaggcca gcgccaataa tcaacaacat
    18541 cagcggaagt ggcagcaaca tattgccaat cacttttttc agtgtaaaaa gcatcctttc
    18601 tggttccttt tttaaccata tagcaaggga tcgccagcga tattacacca gacgggttca
    18661 ttctcgccgt ggctgtgaca aaatagcgtc tttatcagaa aacgtcttag ccaaccggtg
    18721 gagaaagcaa tgcaggatcg caattttgat gatattgcgg aaaagttttc ccgtaacatt
    18781 tacggcacca ccaaagggca gcttcgacag gctattctgt ggcaggatct cgatcgcgtg
    18841 ctggcggaaa tgggcccgca aaaactgcgt gtgctggatg ctggcggtgg agaagggcag
    18901 accgcaatca aaatggccga gcgtgggcat caggtcattt tatgcgatct ttctgcgcag
    18961 atgatcgacc gcgcaaaaca ggcggcagaa gcaaaaggtg tgagcgacaa catgcaattt
    19021 atacattgcg ccgctcagga tgttgcttcg catttggaaa cgcccgttga tctgatattg
    19081 ttccatgcgg tgctcgagtg ggtggctgat ccccgcagcg tattgcagac cctgtggtca
    19141 gtgttgcgtc caggcggcgt gttgtcgtta atgttctaca atgcgcatgg tttgttgatg
    19201 cataacatgg tcgccgggaa ttttgattac gtgcaggcgg gaatgccgaa aaagaaaaaa
    19261 cggacgcttt cgccagatta tccacgcgac ccggcgcagg tttatctgtg gctggaagaa
    19321 gctggttggc aaattatggg taagacaggc gttcgcgtgt ttcatgatta tctgcgcgag
    19381 aaacaccagc agcgcgactg ctatgaagca ttacttgaat tagaaacgcg ttattgccgt
    19441 caggaaccgt atattaccct ggggcgttat attcatgtca ccgcgcgcaa accgcagagc
    19501 aaggataaag tatgagtgaa ttttcccaga cagtccccga actggttgcc tgggccagaa
    19561 aaaatgactt ctccatctcg ctgccggtag accgactctc ttttctgctg gcggttgcca
    19621 cgctgaacgg cgagcgtctg gatggtgaga tgagtgaagg cgagctggtg gatgcattcc
    19681 gccatgtgag tgatgcgttt gagcaaacca gcgaaaccat cggcgtgcgc gccaataacg
    19741 cgatcaacga catggtgcgt caacgtctgt tgaaccgctt taccagcgag caggcggaag
    19801 ggaacgcaat ttaccgtctg acgccgctcg gcatcggcat tactgactac tacatccgtc
    19861 agcgcgagtt ttctacgctg cgtctttcta tgcagttgtc gattgtggcg ggtgagctca
    19921 aacgcgcagc agatgccgcc gaagagggcg gtgatgaatt tcactggcac cgtaatgtct
    19981 atgcgccact gaaatattcg gtagcagaaa ttttcgacag tatcgacctg acgcaacgtc
    20041 tgatggacga acagcagcag caggtgaagg acgatatcgc ccagttgctg aacaaagact
    20101 ggcgggcggc gatttccagc tgtgaattgt tgctttcgga aacttccgga acgctgcgtg
    20161 aattgcagga tacgctggaa gcggcaggcg acaaattgca ggctaatctg ttgcgcattc
    20221 aggatgcgac gatgacccat gacgatctgc atttcgtcga tcgtctggtg ttcgatctgc
    20281 agagcaaact cgatcgtatt atcagttggg gccagcaatc catcgacttg tggattggct
    20341 acgaccgcca cgtacacaaa tttattcgta ccgcgatcga tatggataaa aaccgcgtct
    20401 ttgctcagcg gttacgtcag tcggtacaaa cctattttga tgagccgtgg gcgctaactt
    20461 atgccaatgc cgatcgtctg ctggatatgc gtgacgaaga gatggcactg cgcgatgaag
    20521 aagtgactgg ggaacttcct gaggatctgg aatacgaaga gtttaacgag atccgcgaac
    20581 agctggcggc gatcatcgaa gaacaacttg ccgtgtacaa aaccagacaa gtgccgctgg
    20641 atcttggtct ggtggtacgc gaatatctgt cacagtatcc gcgtgcacgt cactttgacg
    20701 ttgcgcgtat tgttattgat caggcggtac gtcttggcgt agcgcaagca gatttcaccg
    20761 gactgccagc gaaatggcag ccgattaatg attacggagc caaggtacag gcgcatgtca
    20821 tcgacaaata ttgaacaagt gatgccggtt aagctggcgc aggcgctggc gaatccgtta
    20881 tttccggcgc tggacagcgc cttacgttca ggacgccata ttggcctcga cgaactggat
    20941 aatcatgcat tcctgatgga ttttcaggaa tatctggaag agttttacgc gcgttataac
    21001 gttgagctta ttcgcgcacc agaagggttc ttctatttac gcccacgttc caccacgctg
    21061 atccctcgtt ccgtcttgtc ggaactggat atgatggtcg ggaaaatcct ctgttatctc
    21121 tatctcagcc cggaacggct ggcgaatgag gggattttca cccagcagga actgtacgac
    21181 gaactgctca ccctggccga tgaagcaaaa ctgctgaaac tggtgaacaa ccgttcaacc
    21241 ggttcagacg ttgaccgtca gaagttgcag gagaaagtac gttcttcgct caaccgtctg
    21301 cgtcgtttag gcatggtgtg gtttatgggc cacgacagca gcaagtttcg cattaccgaa
    21361 tcggtgttcc gcttcggagc cgatgtgcgt gctggcgacg atccccgtga agcacagcgt
    21421 cgcctgattc gtgatggcga agcaatgccg attgaaaatc atctgcaact caacgatgaa
    21481 accgaagaga atcagccaga tagcggagag gaagaataat gattgaacgc ggtaaatttc
    21541 gctcactgac gctgattaac tggaacggct tttttgcccg aacttttgac cttgacgagc
    21601 tggtcacgac gctttctggc ggtaacgggg cgggtaaatc caccaccatg gcggcgttcg
    21661 ttacggcgct gatccccgac ctgaccctgc tgcatttccg taacactacg gaagccgggg
    21721 ccaccagcgg ttcgcgcgat aaaggtctgc acggtaagct gaaagcgggt gtctgttatt
    21781 cgatgctcga caccattaac tcgcgccacc agcgcgtggt ggtcggtgtg cgtctgcaac
    21841 aggttgccgg acgcgatcgt aaagtggata tcaagccgtt tgccattcag ggactgccga
    21901 tgtcggtgca gccgacacag ctggtgaccg aaaccctgaa cgaacgccag gcgcgcgtgc
    21961 tgccgcttaa cgagctgaaa gacaagctcg aggcgatgga aggcgtgcag tttaaacagt
    22021 tcaactccat tactgattac cactcgctga tgttcgatct gggcatcatc gcgcgtcgtc
    22081 tgcgctccgc atctgaccgt agcaaattct atcgtctgat cgaagcttcg ctgtatggcg
    22141 ggatctccag tgccattacc cgttctctgc gcgactacct gttgccagaa aacagcggcg
    22201 tgcgtaaagc gttccaggac atggaagcgg cgctgcgtga aaaccgtatg acgctggaag
    22261 cgattcgtgt cacccagtcg gaccgcgacc tgtttaagca tctgatcagc gaagccacca
    22321 actacgtggc ggcggactac atgcgtcacg ccaacgagcg ccgtgtccat ctcgacaaag
    22381 ccctggagtt tcgtcgcgag ctacatactt cgcgtcagca actggcggct gagcagtaca
    22441 aacacgtcga tatggcgcgt gagctggcag agcacaacgg tgccgaaggc gatctggaag
    22501 cggattatca ggcggccagt gatcacctga acctggtgca aaccgcactg cgtcagcagg
    22561 agaagatcga acgctacgaa gcggatctcg atgagctgca gatccgtctg gaagagcaaa
    22621 atgaagtggt ggcagaagcc atcgaacgcc aggaagagaa tgaggctcgt gcggaagctg
    22681 ccgaactgga agtggacgag ctgaaaagcc agcttgctga ctaccagcag gcgctggacg
    22741 tccagcaaac gcgcgcgatc cagtataacc aggcgattgc tgcgcttaat cgtgccaaag
    22801 aactgtgcca tctgccggac ttaaccgccg actgcgccgc cgaatggctg gaaaccttcc
    22861 aggcgaaaga gctggaagcg actgaaaaaa tgctctctct tgagcagaaa atgagcatgg
    22921 cgcaaaccgc gcacagccag tttgagcagg cttatcagct ggtggtggca atcaacggcc
    22981 cactggcgcg taacgaggcg tgggatgtcg ctcgcgaact attgcgcgaa ggggtcgatc
    23041 agcgtcacct ggcagagcag gttcagccgc tgcggatgcg attaagcgaa ctggaacagc
    23101 gtctacgcga gcagcaagaa gctgagcgtc tgctggcaga tttctgcaaa cgtcagggca
    23161 agaattttga tatcgacgaa ctggaagccc tgcatcagga actggaagca cgcattgcct
    23221 ctctttccga tagcgtgtct aacgcccgtg aagagcgcat ggcactgcgc caggagcagg
    23281 aacagctgca gtctcgcatt cagagtttga tgcagcgtgc gccggtttgg ctggcagcgc
    23341 aaaacagtct caaccagttg agcgaacagt gcggcgaaga gtttacctcc agccaggacg
    23401 tcaccgaata tctgcaacag ttgctggagc gtgagcgaga ggcgattgtt gaacgcgatg
    23461 aagtgggcgc gcgcaaaaac gccgtcgatg aagagatcga acgtttaagc cagcctggcg
    23521 gctctgaaga tcagcgtctg aacgcgctgg cggagcgttt tggtggtgtg ctgctgtcag
    23581 aaatttatga cgacgttagc ctggaagatg cgccgtactt ctcagcgctg tatggcccgt
    23641 cacgccacgc catcgtggtg ccagatctgt cacaggtaac tgaacacctg gaaggcttga
    23701 ccgattgccc ggaagatctc tatctgatcg aaggagatcc gcagtcattc gatgacagcg
    23761 tgttcagcgt tgatgagctg gaaaaagcgg tagtggtgaa aatcgccgat cgtcagtggc
    23821 gttattcacg tttcccggaa gtgccgctgt ttggtcgtgc tgcgcgtgaa agccgtattg
    23881 aaagcctcca tgccgagcgt gaagtgcttt ccgaacgctt cgccacgctc tcctttgatg
    23941 tacagaaaac tcagcgtctg catcaggcgt tcagccgctt tatcggcagt catctggcgg
    24001 ttgcgtttga gtctgacccg gaagcagaaa tccgtcaact gaacagccgt cgcgtcgaac
    24061 tggagcgggc gttaagtaat catgaaaatg ataaccagca gcagcgtatt cagtttgagc
    24121 aggcgaaaga gggcgttacg gcgctgaacc gcattctgcc gcgtctcaac ctgttggctg
    24181 atgacagcct ggcggatcgc gtcgatgaaa tccgcgaacg tctggatgaa gcccaggaag
    24241 ccgcgcgttt tgttcagcag tttggcaatc aactggcgaa actggaaccg attgtttcgg
    24301 tattgcagag cgacccggaa cagttcgaac agttaaaaga agattacgcg tactctcagc
    24361 agatgcagcg cgatgcccgt cagcaggcgt ttgccctgac ggaagtggtg cagcgtcgtg
    24421 cgcactttag ctattctgac tcggcagaaa tgcttagcgg taacagcgat ctcaacgaaa
    24481 aactgcgtga acgtctggaa caggcggaag cggagcgtac ccgcgctcgc gaagcgttgc
    24541 gcggtcacgc agcgcagttg agtcagtaca accaggtgct ggcttcgctg gaaagttctt
    24601 acgacaccaa aaaagagcta ctcaacgatc tgcaacgtga attgcaggat atcggcgtgc
    24661 gtgctgatag cggggcagaa gagcgggcgc gtattcgccg tgacgagctg catgcgcaac
    24721 tgagcaataa ccgttcacgc cgcaatcaac tggaaaaagc gcttaccttc tgcgaagcgg
    24781 agatggacaa cctgacccgc aaactgcgca agctggagcg ggattacttt gagatgcgcg
    24841 agcaggtagt gaccgccaaa gcgggctggt gtgcggtgat gcgcatggtg aaagataacg
    24901 gcgttgagcg ccgcttacac cgtcgtgagc tggcttatct ctccgctgat gatttgcgtt
    24961 ccatgtcgga taaggcgtta ggtgcgctgc gtctggcggt ggcggataac gaacatctgc
    25021 gcgacgtgct gcgcatgtcg gaagatccga aacgtccgga gcgtaaaatt cagttcttcg
    25081 tggcggttta tcagcatctg cgtgaacgta ttcgtcagga tattattcgt accgatgatc
    25141 cggtggaagc tatcgaacag atggagattg aacttagccg tctgaccgaa gaattaacct
    25201 cccgtgaaca gaaactggcg atcagttccc gcagcgtggc gaacatcatt cgcaaaacca
    25261 ttcagcgcga gcagaaccgt atccgtatgc tcaaccaggg gttgcagaac gtatcgtttg
    25321 gtcaggtgaa cagcgtgcgt ctcaacgtga acgtgcgtga aacgcacgcc atgctactgg
    25381 atgtgctctc tgaacagcac gagcagcatc aggatctgtt taacagcaac cgtttgacct
    25441 tctcggaagc gctggcgaaa ctgtatcaac gtcttaaccc gcagattgat atggggcagc
    25501 gcacgccgca gaccatcggt gaagaactgc tggattaccg caactatctg gaaatggaag
    25561 ttgaggttaa ccgtggttcc gatggctggc tgcgcgcaga gtctggtgca ttgtcgaccg
    25621 gtgaggcgat tggtaccggt atgtcgattc tggtgatggt ggtacaaagc tgggaagatg
    25681 aatctcgccg cctgcgcggt aaagatatct ctccttgccg cctgctgttc ctcgatgaag
    25741 cagcgcgact ggatgctcgt tctatcgcca cgctgtttga attgtgtgag cgtttgcaaa
    25801 tgcaactcat catcgcagcg ccggaaaata tcagcccgga gaaaggcacc acctataaac
    25861 tggtgcgtaa agtcttccag aataccgaac acgttcatgt cgtcggcctg cgaggatttg
    25921 cgccgcaact ccctgaaacg cttccaggaa ctgacgaagc gccttctcag gcgagttaaa
    25981 attaaggcgg cagcaatgcc gccttttctt tttccgaaaa ctccgtttct gcactaaaaa
    26041 agtggcacat tacggcgcgc ttttctttaa acttctttac attaggttat gtaaaaacgt
    26101 atcggcgttt atatactgaa gataagcctg atgagtaaca ggcttgctcg tcatactttc
    26161 gtgagtattg gcgttgtaca ggcaagtcgt aaaataacag cctggctatt cagagtatga
    26221 taaaaacagg gggcaaggga tgttgcttaa tatgatgtgt ggtcgtcggc tgtcggcaat
    26281 cagtttgtgc ctggccgtaa cattcgctcc actgttcaat gcgcaggccg atgagcctga
    26341 agtaatccct ggcgacagcc cggtggctgt cagtgaacag ggcgaggcac tgccgcaggc
    26401 gcaagccacg gcaataatgg cggggatcca gccattgcct gaaggtgcgg cagaaaaagc
    26461 ccgcacgcaa atcgaatctc aattacccgc aggttacaag ccggtttatc ttaaccagct
    26521 tcaactgttg tatgccgcac gcgatatgca acccatgtgg gaaaaccgtg atgctgttaa
    26581 agccttccag caacagctgg cagaggtggc gattgccggt ttccagccgc agtttaataa
    26641 atgggtagag ttactgaccg atcctggtgt taacgggatg gcacgcgacg tggtgctctc
    26701 tgatgcgatg atgggctatc tccatttcat tgcaaatatt ccggtcaaag gcactcgctg
    26761 gctatatagc agtaaacctt atgcacttgc aacgccgccg ctctcggtga ttaaccaatg
    26821 gcagctggcg ctggataaag gtcaattgcc tacgtttgtt gcaggactgg caccgcagca
    26881 tccgcaatat gcggcgatgc atgaatcgtt actggcctta ctctgtgaca ccaaaccgtg
    26941 gccccaactg accggcaaag caacgttgcg cccagggcag tggagtaacg acgtaccggc
    27001 gttgcgcgaa atattgcaac gcacaggcat gttggacggg gggccgaaaa ttactctacc
    27061 tggcgatgac acgccaactg acgcggtagt cagcccatcc gctgttactg ttgaaacagc
    27121 agaaactaag ccgatggata agcaaacgac gtctcgtagt aaacctgcgc ctgccgttcg
    27181 cgccgcctac gataatgaac tggtggaagc cgttaaacgt tttcaggcat ggcaaggatt
    27241 gggggcagat ggtgctattg gcccggcaac acgtgactgg ttaaacgtaa cgcccgccca
    27301 gcgtgctggc gtgttggctc tcaacatcca gcgattgcgc ttgctgccaa cagagctttc
    27361 taccgggatc atggttaaca ttccggccta ttcgctggtc tactatcaga acggcaatca
    27421 ggtgctggat tcgcgagtca ttgtcggtcg ccccgatcgc aaaacgccga tgatgagcag
    27481 tgcccttaac aacgtagtgg taaacccgcc gtggaacgta cctccaactc tggcacgcaa
    27541 agatattctg ccaaaagtgc gcaacgatcc gggatatctc gaaagccatg gctatacggt
    27601 gatgcgtggc tggaacagca gagaagcgat tgacccatgg caggttgact ggtctacaat
    27661 cacggcctcg aatttaccgt tccgcttcca gcaggctcca ggcccacgga actcgctggg
    27721 gcgctataaa ttcaatatgc cgagttcaga ggccatttat ttgcatgaca cgccgaacca
    27781 caatctgttc aagcgtgata cacgcgcatt gagctcaggc tgtgtacgag tgaataaagc
    27841 ttccgatctg gcgaatatgc tgttgcagga tgcaggctgg aatgacaaac gtatttctga
    27901 tgcgctgaag cagggtgata cacgttacgt caatattcgg cagtcgattc cggtgaatct
    27961 ctactacctg acggcctttg ttggtgcaga tggtcgtacc cagtatcgta cagatattta
    28021 caattatgat ctgcctgcgc gatccagctc gcaaatcgta tcgaaagcgg aacaattaat
    28081 caggtaaatg aagtagttcg gggaaatcag ttgtcgtaat aattagcatg attgggggcg
    28141 attctctgca gcccccgtca ctgctggggt tgagtcatct tgacgtctgc tttacgggcg
    28201 gttaaggtgc ctcttgtgcg ccagaagtgc atataaacga taacattgac ctgtagactt
    28261 gattatcatg gacaaattcg acgctaatcg ccgcaaattg ctggcgcttg gtggcgttgc
    28321 actcggtgcc gccatcctgc cgacccctgc gtttgcaaca ctctctaccc cacgcccgcg
    28381 cattttgaca ctcaataatc ttcataccgg agagtcaatc aaagcggagt ttttcgatgg
    28441 cagaggctat attcaggaag aattggcaaa acttaaccat tttttccgcg attaccgcgc
    28501 gaacaaaata aagtccatcg acccaggatt attcgaccag ttgtatcgcc tgcaagggtt
    28561 gttaggcacg cgcaaaccgg tgcaactcat ttccggttat cgttctattg ataccaacaa
    28621 tgaactacgc gcccgcagcc gtggagtagc gaagaaaagc tatcacacta aaggccaggc
    28681 gatggatttc catattgaag gtatcgcgtt aagcaatatt cgcaaagccg cgttatctat
    28741 gcgcgcaggt ggtgtaggat attatccacg tagtaacttt gtgcatattg ataccgggcc
    28801 agcacggcac tggtagtaat tgcttaacga aacaggggca gtatgaacta tcgtattatt
    28861 ccggtcaccg cattctccca gaactgttca ttaatctggt gtgaacaaac ccgtctggcc
    28921 gcactggtcg atcctggcgg cgatgcggaa aaaatcaaac aggaagttga tgacagcggc
    28981 ctgacactga tgcagatcct gctgacgcat ggtcatctgg accacgttgg cgcagcggcg
    29041 gaactggcgc aacattacgg cgtgccggtt ttcggcccgg aaaaagaaga tgagttctgg
    29101 ctgcaaggct tgcctgcgca aagtcgtatg tttggtctgg aagagtgcca gccgctgacg
    29161 ccagatcgtt ggctgaacga aggcgatacc atcagcatag ggaatgtgac tttacaggtg
    29221 ttacattgcc ctgggcatac gccgggtcat gtcgtgtttt ttgatgatcg ggcaaagctg
    29281 ctgatttctg gcgatgttat tttcaaaggc ggagtagggc gcagtgactt cccgcgtggc
    29341 gatcataatc aactgatttc ttcaatcaaa gataaattgc tgccactggg ggatgacgtg
    29401 atatttattc cgggtcacgg accattatcc acacttggtt atgaacgcct gcataatccc
    29461 ttcctgcaag acgaaatgcc cgtctggtaa ggcacataaa aaagcccgct tttaatgcgg
    29521 gcctggattt ctggcaaagt gcgctttgtt tatgccggat gcggcacgag cgccttatcc
    29581 ggcctacaaa atcgtgcaaa ttcaaaatat tgcaggggac gcgtaggcct gataagcgta
    29641 gcgcatcagg caatgttgcg tttgtcatca gtctcagccc gcttttcagc gggcttcatt
    29701 gtttttaatg cttacagcac tgccacaatc gcttcgcaca gcggagccat gttatctggt
    29761 gtcatcccgg ccacatttac gcgaccagaa gcaaccgcat atacgccaaa ctcttcgcgc
    29821 agacgcagca cttgttcttt tgtcaggcca ctgaaggaga acatgccgtt ctgtttgatg
    29881 ataaagctga agtcgcggtt tgcgcctttt tcctgcagcg tattgacgaa caactgacgc
    29941 atacgctgaa tacgctggcg catatcagtc agctcttgtt cccaaatcgc acgtaacgca
    30001 tcgttgctca ggatggtggc aacaacagaa gcgccgtgtg ctggtgggtt agagtagtta
    30061 gcgcgaatcg ccgctttcat ttggctgaat gcgcgatcaa cggtttcact gtcggcagca
    30121 accagagtac aagcgccaac acgctcgttg tacaggccaa agtttttaga gtaggaactg
    30181 gcaacaatca gctctttatg catagccgcg aaagcgcgca gtccttcagc atcttcttcc
    30241 agaccacggg caaaaccctg gtaagcgaag tcaaacagcg gtaaccagcc tttctcaacg
    30301 gagagttgtg ccagtgtttg ccattgttcc agcgtagggt cgataccggt tgggttatgg
    30361 cagcagccat ggaacagcac tacgtcgcca gcctgagctt cattcaggct gttaatcagt
    30421 gcatcgaagt caagagtgtg attttccgca tcataataag cgtattcacg aacttccaga
    30481 cctgcagagt taaagacgct cttatggttc ggccagcttg ggttgctcac ccacacacgc
    30541 ttaacgctgg tattttttgc caggaaatcg gcagccacgc gtagtgcgcc agtgcccccc
    30601 ggagtctgtg ccgtgcgagc acgtttgtca ttgatcaggg cgctaccttt accaaacagc
    30661 agttcctgag tgcagcgacc aaattcaggg atgccgtcaa tgccgaggta atttttggtg
    30721 gtttcatttt cgagcagata ctgttcagcc tttttcacgc tggtcagtac cggggttttg
    30781 cccgtctcat ctttatagac accaatcccg aggttaattt tgccgggacg ttcatcggca
    30841 cgaaacagat cggccaggcc cagaatcggg tcggcaggag cggcggtaat gttctcaaac
    30901 atgacgaggt tccattatgg ttacagaagg gaagtccgct atcagggtaa cgggagattt
    30961 acaaaattcc aactattact gatgaaaacg caggctgttt ttgcaagacg tgagattgct
    31021 ctggaaggta taaaaaaaac aggaccaaag tcctgttttt tcggcattta acaaagaggt
    31081 gtgctattag aactggtaaa cgatacccac agcaacggtg tcgtctgaac ctacgcccag
    31141 tttgttgtca gaatcgatct ggttgatgat gtagtcaaca taggtggaca tgtttttgtt
    31201 gaagtagtag gttgcgccca cttcaaagta gttcaccaga tcaacatcac cgataccttc
    31261 tacgtctttc gctttagatt tggtgtaagc gatggacgga cgcagaccga aatcgaactg
    31321 gtattgcgca actaacagaa cgtcttgcgt tttgttggcg aagccgctgg tgtttgtaaa
    31381 tttattagtg atcggcgtag cgttacgggt ttcaccgtag ttcgctgcca ggtagatgtt
    31441 gttcgcgtcg tacttcagac cagtagccca ctgttcagct tttttaccgt tgccaagagg
    31501 ttgagcttct tgcaggttgg tacggtcagc tgcaccataa gcaccaacga taccaaagcc
    31561 ttcgtattcg tagctgatag aaccgccaac accgtcgccg ttagaacggc gtgcagtgtc
    31621 acgctcgttt ttacccaggt actgaacagc gaagttcagg ccatcaacca gaccaaagaa
    31681 gttggagtta cgataggtag caacgccgcc aacacgacca acgaagaagt catcgctgta
    31741 tgcagtatca ccaccaaatt ctggcagcat atcggtgtaa cccagtgcat cataaaccac
    31801 accgtagtta cggccgtaat cgaaagaacc aacgtcagcg tatttaagac ccgcgaatgc
    31861 cagacgcgtt ttgttaccag tttgagcgtc agcgccttca gagttgttac cctggaagtt
    31921 atattcccac tgaccataac cggtcagatc ggaattgatt tgagtttccc ctttaaaacc
    31981 aagacgggca taggtcatgt cgccattgcc accgtaactg ttttcaccgt tacccttgga
    32041 aaaataatgc agaccaacag ctttaccgta cagatctact ttgttgccat ctttgttata
    32101 gatttctgca gcgtttgcag tacctgctac taacagagca gggacgatca ctgccagaat
    32161 attgcgcttc atcattattt attaccctca tggttttttt tatgacacct gccactgccg
    32221 tcaataagtt ctgtcaataa aaatttacgg aactattgat gagagtttgg tgtctttatg
    32281 tgtctgcagg catctttcca ttcaaactaa cgtttcgcta ccgtgaaagt gctacaaaga
    32341 taaagatttg gtttcaaaaa gaaaaaatat gtaaccaaaa gtaa
//
LOCUS       DAPHKZ010000043        32123 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.043, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000043 DAPHKZ010000000
VERSION     DAPHKZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32123
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.043"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(53..943)
                     /gene="rarD"
                     /locus_tag="RH288_002126"
     CDS             complement(53..943)
                     /gene="rarD"
                     /locus_tag="RH288_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HDV4031175.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSAVLIGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIA
                     AGIVTTVPLLCFTAAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTFAFI
                     WVALAIFVMDAIYTQRRTSK"
     gene            complement(995..1462)
                     /locus_tag="RH288_002127"
     CDS             complement(995..1462)
                     /locus_tag="RH288_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HDV4031176.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAF
                     KNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG"
     gene            1627..2496
                     /gene="pldA"
                     /locus_tag="RH288_002128"
     CDS             1627..2496
                     /gene="pldA"
                     /locus_tag="RH288_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HDV4031177.1"
                     /translation="MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLK
                     IGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDLF"
     gene            2629..4458
                     /gene="recQ"
                     /locus_tag="RH288_002129"
     CDS             2629..4458
                     /gene="recQ"
                     /locus_tag="RH288_002129"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDV4031178.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCL
                     VVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTRE
                     QQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDY
                     GHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSL
                     QLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEM
                     AEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE"
     gene            4522..5142
                     /gene="rhtC"
                     /locus_tag="RH288_002130"
     CDS             4522..5142
                     /gene="rhtC"
                     /locus_tag="RH288_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HDV4031179.1"
                     /translation="MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEAVSAP
                     APQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVET
                     LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(5204..5824)
                     /gene="rhtB"
                     /locus_tag="RH288_002131"
     CDS             complement(5204..5824)
                     /gene="rhtB"
                     /locus_tag="RH288_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HDV4031180.1"
                     /translation="MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIA
                     GLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSL
                     ASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
                     VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA"
     gene            5935..6957
                     /gene="pldB"
                     /locus_tag="RH288_002132"
     CDS             5935..6957
                     /gene="pldB"
                     /locus_tag="RH288_002132"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HDV4031181.1"
                     /translation="MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVR
                     FVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHLGFDVLIIDHRGQGRSGRLLADP
                     HLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
                     LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRY
                     RRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNR
                     MHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSG
                     NRSTEV"
     gene            6965..7765
                     /gene="yigL"
                     /locus_tag="RH288_002133"
     CDS             6965..7765
                     /gene="yigL"
                     /locus_tag="RH288_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HDV4031182.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII
                     TNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND
                     AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS"
     gene            7841..8740
                     /gene="bioP"
                     /locus_tag="RH288_002134"
     CDS             7841..8740
                     /gene="bioP"
                     /locus_tag="RH288_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter"
                     /protein_id="HDV4031183.1"
                     /translation="MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFL
                     PFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIY
                     DIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVH
                     RKWVAPRSSQTADDRRRDCALSE"
     gene            complement(8628..9581)
                     /gene="metR"
                     /locus_tag="RH288_002135"
     CDS             complement(8628..9581)
                     /gene="metR"
                     /locus_tag="RH288_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HDV4031184.1"
                     /translation="MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQP
                     VTEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL"
     gene            9818..12079
                     /gene="metE"
                     /locus_tag="RH288_002136"
     CDS             9818..12079
                     /gene="metE"
                     /locus_tag="RH288_002136"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDV4031185.1"
                     /translation="MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELR
                     ARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPV
                     LLGPVTWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELP
                     QAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAEL
                     HKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSV
                     ETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAV
                     EKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKG
                     NLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEA
                     FRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAAL
                     ANMVQAAQNLRRG"
     gene            complement(12119..12934)
                     /locus_tag="RH288_002137"
     CDS             complement(12119..12934)
                     /locus_tag="RH288_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312787.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDV4031186.1"
                     /translation="MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPA
                     YHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLTGDKSLNSPKQPVDIATDLNAPVLGLYGGLDNSIPQESVETMRQA
                     LRAANAKAEIIVYPDAGHAFNADYRPSYHAASAKDGWQRMLEWFKQYGGKKSL"
     gene            13196..13957
                     /gene="udp"
                     /locus_tag="RH288_002138"
     CDS             13196..13957
                     /gene="udp"
                     /locus_tag="RH288_002138"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HDV4031187.1"
                     /translation="MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKL
                     ASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESQAVKIVVEAARRLL"
     gene            14098..15525
                     /gene="rmuC"
                     /locus_tag="RH288_002139"
     CDS             14098..15525
                     /gene="rmuC"
                     /locus_tag="RH288_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HDV4031188.1"
                     /translation="MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAE
                     LSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR
                     QMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
                     GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASG
                     LREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTR
                     ESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITE
                     ALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAI
                     GQSLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEY
                     RLRSVPEQPNDEAYQRDDEYNQQSR"
     gene            15620..16375
                     /gene="ubiE"
                     /locus_tag="RH288_002140"
     CDS             15620..16375
                     /gene="ubiE"
                     /locus_tag="RH288_002140"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HDV4031189.1"
                     /translation="MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCISISFGLRNVTDKDKALRSMYRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQ
                     DTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            16389..16994
                     /gene="ubiJ"
                     /locus_tag="RH288_002141"
     CDS             16389..16994
                     /gene="ubiJ"
                     /locus_tag="RH288_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HDV4031190.1"
                     /translation="MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGF
                     STSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLTALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKAMRGGAKFLHHGIKRQQRYVAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK"
     gene            16991..18631
                     /gene="ubiB"
                     /locus_tag="RH288_002142"
     CDS             16991..18631
                     /gene="ubiB"
                     /locus_tag="RH288_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HDV4031191.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWM
                     PNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDG
                     KLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFF
                     TQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAF
                     KEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGAT
                     LVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR"
     gene            18710..18979
                     /gene="tatA"
                     /locus_tag="RH288_002143"
     CDS             18710..18979
                     /gene="tatA"
                     /locus_tag="RH288_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HDV4031192.1"
                     /translation="MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDEPKQAKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV"
     gene            18983..19498
                     /gene="tatB"
                     /locus_tag="RH288_002144"
     CDS             18983..19498
                     /gene="tatB"
                     /locus_tag="RH288_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HDV4031193.1"
                     /translation="MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPE
                     KASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
                     AAPSPSSSDKP"
     gene            19501..20277
                     /gene="tatC"
                     /locus_tag="RH288_002145"
     CDS             19501..20277
                     /gene="tatC"
                     /locus_tag="RH288_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HDV4031194.1"
                     /translation="MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHL
                     VSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE"
     gene            20319..21101
                     /gene="tatD"
                     /locus_tag="RH288_002146"
     CDS             20319..21101
                     /gene="tatD"
                     /locus_tag="RH288_002146"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HDV4031195.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVARAFDAGVNGLLITGTNLRESQQ
                     AQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFST
                     PEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
                     MQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSS
                     RRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF"
     gene            complement(21098..21586)
                     /gene="rfaH"
                     /locus_tag="RH288_002147"
     CDS             complement(21098..21586)
                     /gene="rfaH"
                     /locus_tag="RH288_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HDV4031196.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRT
                     AVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPK
                     DIVDPATPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
                     KL"
     gene            21753..23246
                     /gene="ubiD"
                     /locus_tag="RH288_002148"
     CDS             21753..23246
                     /gene="ubiD"
                     /locus_tag="RH288_002148"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HDV4031197.1"
                     /translation="MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGY
                     IEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA"
     gene            23292..23993
                     /gene="fre"
                     /locus_tag="RH288_002149"
     CDS             23292..23993
                     /gene="fre"
                     /locus_tag="RH288_002149"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HDV4031198.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDE
                     ERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHP
                     GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSER
                     NAREDRLFGDAFAFI"
     gene            complement(24276..25439)
                     /gene="fadA"
                     /locus_tag="RH288_002150"
     CDS             complement(24276..25439)
                     /gene="fadA"
                     /locus_tag="RH288_002150"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HDV4031199.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPA
                     LEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
                     SREMQDAFAARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LATLRPAFDPVNGMVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLIEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV"
     gene            complement(25449..27638)
                     /gene="fadB"
                     /locus_tag="RH288_002151"
     CDS             complement(25449..27638)
                     /gene="fadB"
                     /locus_tag="RH288_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HDV4031200.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIG
                     VLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
                     DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAILRQAINGDLDWKAKRQPK
                     LEPLKLSKIEATMSFTIAKGIVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDIETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVIMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDVVVEAVVENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     DYRDTIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAVVDDLLAEVSQPKRDFSE
                     EEIIARMMIPMVNEVVRCLEESIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAK
                     YLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA"
     gene            27828..29159
                     /gene="pepQ"
                     /locus_tag="RH288_002152"
     CDS             27828..29159
                     /gene="pepQ"
                     /locus_tag="RH288_002152"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HDV4031201.1"
                     /translation="MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     DVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
                     FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIES
                     LLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA"
     gene            29159..29773
                     /locus_tag="RH288_002153"
     CDS             29159..29773
                     /locus_tag="RH288_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HDV4031202.1"
                     /translation="MESWLIPAAPVTVVEEIKKSRFITMLAHTDGVEAAKAFVESVRA
                     EHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYSQLTGIEALLGQCDG
                     KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE"
     gene            29812..31263
                     /gene="trkH"
                     /locus_tag="RH288_002154"
     CDS             29812..31263
                     /gene="trkH"
                     /locus_tag="RH288_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HDV4031203.1"
                     /translation="MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFF
                     VALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATI
                     AIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQFTLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            31275..31820
                     /gene="hemG"
                     /locus_tag="RH288_002155"
     CDS             31275..31820
                     /gene="hemG"
                     /locus_tag="RH288_002155"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HDV4031204.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKELGIQTDVANVHRIEEPQ
                     WENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTN
                     SYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTD
                     WEQVANFAREIAHLTDKPTLK"
BASE COUNT         7451 a         8197 c         8796 g         7679 t
ORIGIN      
        1 atgcccactc tcatgcaaga gtcggcatat tttttcagaa tatatttatt ttttatttgg
       61 acgttctacg ctgcgtataa atcgcatcca tcacaaaaat tgccagcgcc acccaaataa
      121 aggcgaaagt caccatctta tcggcacccg gtttttcacc ataaaacgtc acagccagca
      181 ggaacatcag cgtcgggcca atgtactgga aaaagcctaa cgttgagaga cgcaagcgcg
      241 tggcagcggc ggtaaaacac aacagcggta cggtagtgac aataccggcg gcgatcagca
      301 gtaaattcag cgacatcggg ttttgcccca tatggctggt tgagctgtcg gcaatagcaa
      361 acaggtaaat tgccgccacg ggcagcagcc acatggtttc gattaacatg ccggtttgcg
      421 cttcaacggc aatcttcttg cgtaccagac cgtagaaggc aaaactaaat gccagtccca
      481 gcgcgataat aggtagcgaa ccaaaagtcc acagctggac taacacgcca catatcgcca
      541 gaatcaccgc cagccattgc atccggcgga atcgctcgcc gaggaaaatc atccccagca
      601 caatgttcac cagcgggtta ataaagtaac caaggctcgc ttccagcata tggtgattgt
      661 tcaccgccca gataaacagt agccagttgc caccaatcag cacggcagag actgccagca
      721 taaaaatttt ctgtggcgtc tgaatcagcg tttttaaata ggaccactgg cggcaaatgc
      781 tcatcagcac caccataaag aaaaacgacc agatcacgcg atgcgtcagg atttcatcgg
      841 cgggcacgta gtaaatcaac ttgaagtacg ctggcgctat accccaaata aaataagcgg
      901 caagagcgag taatacgccc tgccgcgttt gttttgcatc catcgggaat actcattttt
      961 aattggtaac agcagtttac ctgcttttat gtcttcaacc taccatatag gtggcggtgg
     1021 cactggcaat ataaagctgt tcttcattgt gtaattcaac gcgggcgacg gcgactttat
     1081 tgcctgcacg caacaggcta ctagtagcag taaaacgctc gcccctgcct gggcgcagat
     1141 aatcaacgcg aagatcaatg gtccccatcc gcgatagccg ctggcgtagt tcatcttcac
     1201 tgatggtttc gtggcgggtt aaggtacttc ccacgcacac cagaccggcg gcgacatcca
     1261 gcgccgacgc aatgaccccg ccgtgcaaaa tgctttgcgc ccagttgccc accatcattg
     1321 gctgattttt aaaggccagc tgtgcgaact ctttttcgta acgctccagt tccatcccca
     1381 atgcgcggtt aaatggcatg tgataaacaa acatctcacc cactaatttc agggcttgtt
     1441 cagcggtcag tacggcagac atatcatcct tacacttcat tggttaatga aatgttgatt
     1501 ttatgcttct ttgttgttgg tttctacttt aggaagggat aactaacggc tatggagtta
     1561 agtatgtaaa atagcccgca gaaaaatatt caccttatca ataattcgtt acggagaaca
     1621 cgaccgatgc ggactctgca gggctggttg ttgccggtgt ttatgttgcc tatggcagta
     1681 tatgcacaag aggcaacggt gaaagaggtg catgacgcgc cagcggtgcg tggcagtatt
     1741 atcgccaata tgctgcagga gcatgacaat ccgttcacgc tctatcctta tgacaccaac
     1801 tacctcattt acacccaaac cagcgatctg aataaagaag cgattgccag ttacgactgg
     1861 gcggaaaatg cgcgtaagga tgaagtaaag tttcagttga gcctggcatt tccgctgtgg
     1921 cgtgggattt taggcccgaa ctcggtgttg ggtgcgtctt atacgcaaaa atcctggtgg
     1981 caactgtcca atagcgaaga gtcttcaccg tttcgtgaaa ccaactacga accgcaattg
     2041 ttcctcggtt ttgccaccga ttaccgtttt gcaggttgga cgctgcgcga tgtggagatg
     2101 gggtataacc acgactctaa cgggcgttcc gacccgacct cccgcagctg gaaccgcctt
     2161 tatactcgcc tgatggcaga aaacggtaac tggctggtag aagtgaagcc gtggtatgtg
     2221 gtgggtaata ctgacgataa cccggatatc accaaatata tgggttacta ccagcttaaa
     2281 atcggctatc acctcggtga tgcggtgctc agtgcgaaag gacagtacaa ctggaacacc
     2341 ggctacggcg gcgcggagtt aggcttaagt tacccgatca ccaaacatgt gcgcctttat
     2401 actcaggttt acagcggcta tggcgaatcg ctcatcgact ataacttcaa ccagacccgt
     2461 gtcggtgtgg gggttatgct aaacgatttg ttttgatgaa cggttgagtg gttggcaaat
     2521 ctggaatcca gcatccagga ttaccctctc agagactaaa agcattgcag tttctcgcgc
     2581 aggcgctgaa aatagcgcct gtttttattt caggcaatcg gggtgaatgt ggcgcaggcg
     2641 gaagtgttga atctggagtc cggagctaaa caggttttac aagaaacctt tggctaccaa
     2701 cagtttcgcc ccggccagga agaaattatc gacactgtgc tttccggccg cgattgcctc
     2761 gtcgtcatgc ccactggtgg cggaaaatcc ctttgctatc aaatccctgc cttattgcta
     2821 aacggcctta ccgtggttgt ttcaccgctg atttcgttga tgaaagatca ggtggatcaa
     2881 ctgcaagcca acggcgtggc ggcggcgtgc cttaactcga cgcaaacccg cgaacagcaa
     2941 cttgaagtga tgacaggctg ccgcaccggg caaattcgtc tgctttatat cgccccggaa
     3001 cgcctgatgc tggataactt tcttgagcat ctggcgcact ggaatccggt gttattagcc
     3061 gttgatgaag cgcactgtat ctcccaatgg ggccacgatt ttcgcccgga atatgccgcg
     3121 ctcggtcagt tgcgccagcg gttcccgacg ctgccgttta tggcgctgac cgccacagcc
     3181 gacgacacca cgcgccagga tatcgtgcgc ctgctggggc tgaacgatcc gctgattcaa
     3241 atcagcagtt ttgaccgtcc gaatattcgc tacatgctga tggagaagtt caaaccgctc
     3301 gatcagttga tgcgctacgt gcaggaacag cgcggtaagt caggcattat ctactgcaac
     3361 agccgcgcga aagtagaaga caccgctgcg cgcctgcaaa gcaagggaat tagcgcggcg
     3421 gcctatcatg ccgggctgga aaataatgtt cgcgccgatg tgcaggaaaa attccagcgc
     3481 gatgacctgc aaattgtggt ggcgacggtg gcgttcggca tgggcatcaa taaaccaaac
     3541 gttcgcttcg tggtccactt tgatattccg cgcaatatcg aatcctatta tcaggaaacc
     3601 ggacgcgccg ggcgtgatgg cctgcccgcg gaagcgatgc tgttttacga tccggctgat
     3661 atggcgtggc tgcgccgttg tctggaagag aagccgcagg ggcagttgca ggatatcgag
     3721 cgccacaaac tcaatgcgat gggcgcgttt gccgaagcgc aaacttgccg tcgtctggta
     3781 ttgctgaact attttggcga agggcgtcag gagccgtgcg ggaactgcga tatctgcctc
     3841 gatccgccga aacagtacga cggttcaacc gatgctcaga ttgccctttc caccattggt
     3901 cgtgtgaatc agcggtttgg gatgggttat gtggtggaag tgattcgtgg tgctaataac
     3961 cagcgtatcc gcgactatgg tcatgacaaa ctgaaagtct atggcatggg ccgtgataaa
     4021 agccatgaac attgggtgag cgtgatccgc cagctgattc acctcggcct ggtgacgcaa
     4081 aatattgccc agcattctgc cctacaactg acagaggccg cgcgcccggt gctgcgcggc
     4141 gaatcctctt tgcaacttgc cgtgccgcgt atcgtggcgc tcaaaccgaa agcgatgcag
     4201 aaatcgttcg gcggcaacta tgatcgcaaa ctgttcgcca aattacgcaa actgcgtaaa
     4261 tcgatagccg atgaaagtaa tgtcccgccg tacgtggtgt ttaacgacgc aaccttgatt
     4321 gagatggctg aacagatgcc gatcaccgcc agcgaaatgc tcagcgttaa cggcgttggg
     4381 atgcgcaagc tggaacgctt tggcaaaccg tttatggcgc tgattcgtgc gcatgttgat
     4441 ggcgatgacg aagagtagtc agcagcataa aaaagtgcca gtatgaagac tccgtaaacg
     4501 tttcccccgc gagtcaaatg tatgttgatg ttatttctca ccgtcgccat ggtgcacatt
     4561 gtggcgctta tgagccccgg tcccgatttc ttttttgtct ctcagaccgc tgtcagtcgt
     4621 tcccgtaaag aagcgatgat gggcgtgctg ggcattacct gcggcgtaat ggtttgggct
     4681 gggattgcgc tgcttggcct gcatttgatt atcgaaaaaa tggcctggct gcatacgctg
     4741 attatggtgg gcggtggcct gtatctctgc tggatgggtt accagatgct acgcggtgca
     4801 ctgaaaaaag aggcggtttc tgcacctgcg ccacaggtcg agctggcgaa aagtgggcgc
     4861 agtttcctga aaggtttact gaccaatctc gctaatccga aagcgattat ctactttggc
     4921 tcggtgttct cattgtttgt cggtgataac gttggcacta ccgcgcgctg gggcattttt
     4981 gcgctgatca ttgtcgaaac gctggcgtgg tttaccgtcg ttgccagcct gtttgccctg
     5041 ccgcaaatgc gccgtggtta tcaacgtctg gcgaagtgga ttgatggttt tgccggggcg
     5101 ttatttgccg gatttggcat tcatttgatt atttcgcggt gatgccagac gcgtcttcag
     5161 agtaagtcgg ataaggcgtt tacgccgcat ccgacattat ttttcacgca tgcctcgccg
     5221 atgctaacag cgctcccacc agcataaaca acgagccgaa aatcttattc agcgccttca
     5281 tctgctttgg tcctttaatc catagagcaa tccgttgagc aagggtggcg taaccgatca
     5341 tcacaataat atcgaccaca atagtggtga cgccgagcac gatatactgc atcagttgcg
     5401 gctgttgcgg catgatgaat tgcggaaata gcgccgccag aaacacaata cttttgggat
     5461 tggtgagatt cacaaaaact gcgcgctgga acaaatgtcg acgcgattga gtagaggcca
     5521 gcgatttaag gtcaattgca ccagcggcgc gccactgctg gattcccagc caaatcaagt
     5581 aagccgcgcc tgcccacttc aacacttcaa acgcaatcac tgagcgggaa aatagcgtcc
     5641 ccaaccccac gccaaccagc acaatatgaa tcgccagtcc ggtctgaagc ccagcaatag
     5701 acgccaccgc gccgcgataa ccgtggttga gcgaggtggt catagtgttg attgcaccag
     5761 agcctggcga caggcttaaa atgatcgatg tcagcaggta ggcaaaccac cattctaagg
     5821 tcatgatgaa ctcccggtgt gtctattttt gtgccacaat acgctactgt cgcagcgttg
     5881 tgtcaggcac gctaaaaaaa acgattttac gtggtttaag aggcagatta cccgatgttt
     5941 cagcagcaaa aagactggga aacaagagaa aacgcgtttg ctgcttttac catgggaccg
     6001 ctgactgatt tctggcgtca gcgtgatgaa gcagagttta ctggtgtgga tgacattccg
     6061 gtgcgctttg tccgttttcg cgcacagcac catgaccggg tggtagtcat ctgcccgggg
     6121 cgtattgaga gctacgtaaa atatgcggaa ctggcctatg acctgttcca tttggggttt
     6181 gatgtcttaa tcatcgacca tcgcgggcag ggacgttccg gtcgcctgtt agccgatccg
     6241 catctcgggc atgttaatcg ctttaatgat tatgttgatg atctggcggc attctggcag
     6301 caggaggttc agcccggtcc gtggcgtaaa cgctatatac tggcacattc gatgggcggt
     6361 gcgatctcca cattatttct gcaacgccat ccaggtgtat gtgacgccat tgcgctaact
     6421 gcgccaatgt ttgggatcgt gattcgtatg ccgtcattta tggcacggca gatcctcaac
     6481 tgggccgaag cgcatccacg tttccgtgat ggctatgcaa taggcaccgg gcgctggcgc
     6541 gcgttgccgt ttgctatcaa cgtactgacc cacagcagac agcgatatcg acgtaactta
     6601 cgcttctatg ctgatgaccc aacgattcgc gtcggtgggc cgacctacca ttgggtacgc
     6661 gaaagtattc tggctggcga acaggtgtta gccggtgcgg gtgatgacgc cacgccaacg
     6721 cttctcttgc aggctgaaga ggaacgcgtg gtggataacc gcatgcatga ccgtttttgt
     6781 gaactccgca ccgccgcggg ccatcctgtc gaaggaggac ggccgttggt aattaaaggt
     6841 gcttaccatg agatcctttt tgaaaaggac gcaatgcgct cagtcgcgct ccacgccatc
     6901 gttgattttt tcaacaggca taactcaccc agcggaaacc gctctacaga ggtttaaatt
     6961 tcttatgtac caggttgttg cgtctgattt agatggcacg ttactttctc ccgaccatac
     7021 gttatcccct tacgccaaag aaactctgaa gctgctcacc gcgcgcggca tcaactttgt
     7081 gtttgcgacc ggtcgtcacc acgttgatgt ggggcaaatt cgcgataatc tggagattaa
     7141 gtcttacatg attacctcca atggtgcgcg cgttcacgat ctggatggta atctgatttt
     7201 tgctcataac ctggatcgcg acattgccag cgatctgttt ggcgtagtca acgacaatcc
     7261 ggacatcatt actaacgttt atcgcgacga cgaatggttt atgaatcgcc atcgcccgga
     7321 agagatgcgc ttttttaaag aagcggtgtt ccaatatgcg ctgtatgagc ctggattact
     7381 ggagccggaa ggcgtcagca aagtgttctt cacctgcgat tcccatgaac aactgctgcc
     7441 gctggagcag gcgattaacg ctcgttgggg cgatcgcgtc aacgtcagtt tctctacctt
     7501 aacctgtctg gaagtgatgg cgggcggcgt ttcaaaaggc catgcgctgg aagcggtggc
     7561 gaagaaactg ggctacagcc tgaaggattg tattgcgttt ggtgacggga tgaacgacgc
     7621 cgaaatgctg tcgatggcgg ggaaaggctg cattatgggc agtgcgcacc agcgtctgaa
     7681 agaccttcat cccgagctgg aagtgattgg tactaatgcc gacgacgcgg tgccgcatta
     7741 tctgcgtaaa ctctatttat cgtaatcgtt ctttatttgg tcagttgtca acctgatact
     7801 tcgctacaat ggatacccgt taatcaaaga gttttccatt gtggcgctac ttatcatcac
     7861 cacgattctg tgggccttct cctttagctt ttatggcgag taccttgcgg ggcacgtcga
     7921 tagctatttt gcggtgctgg tgcgcgttgg cctggcggca ctcgtttttc tgccgtttct
     7981 gcgtacccgt ggcaatagcc tgaaaacggt cggcctgtat atgctggtgg gcgcgatgca
     8041 gcttggcgtg atgtatatgc tgagtttccg cgcttatctc tacctgacgg tttccgagct
     8101 gctgctgttc accgtgctga cgccgctcta catcacgctg atttatgaca tcatgagtaa
     8161 gcgccgtctg cgctggggct atgcctttag cgccttgctg gcggtgattg gtgccgggat
     8221 tattcgctat gatcaggtca ccgaccattt ctggactggc ttgctgctgg tgcaactctc
     8281 caatatcact tttgccattg gcatggtggg ttacaaacgc ctgatggaaa ctcgcccgat
     8341 gccacagcat aacgcctttg cgtggttcta tcttggcgcg tttctggtgg cagtgattgc
     8401 atggttcttg ctgggaaatg cgcagaaaat gccgcaaacc acgctgcaat ggggcattct
     8461 ggtgtttctt ggcgtggtgg cttccgggat tggctacttt atgtggaact acggcgcgac
     8521 gcaggtggac gccggaacgc tgggcattat gaataatatg cacgttccgg cagggctgct
     8581 ggtaaacctg gctatctggc accaacagcc gcactggcca acgtttatta caggcgcgct
     8641 ggtgatcctg gcctcactgt gggtgcatcg taagtgggtc gctccgcgct cttcacaaac
     8701 ggcagatgat cgcaggcgtg attgcgcgct gagcgaataa acgcttccgt aactggctga
     8761 cgctgctcgc catcgcgcac ggcggcgtac agtcggctcc acaagccttc gcccagggtt
     8821 ttggtcacca ccagaccctg gcgctcaaaa ctctctacta cccaatgcgg tagcgcggca
     8881 atacccatcc gcgcggcaac catctgaatc aacaataagg tgttatcgac gcttttcagt
     8941 gacgggctga cgcctgccgg ctgaagaaaa tgccgccaga catccagtcg actacgctgc
     9001 accggataaa ttaatagcgt ctcgctggcg agatcttccg gtgtaattcg cgttttcgcc
     9061 gccagtggat ggtcaggtgc taacaccaga cgcacttcat agtcgaacat cggcgaataa
     9121 tgcaggccac tgcgcggcag aatatcggac gtcattacca gatccagctc tccctgttgc
     9181 aaggcgggct gcgggtcaaa tgtcacgccc gatttaaaat ccatctctac ctgcggccag
     9241 ttcttatgga aattttctaa cgcgggtgtc agccactgaa tacagctatg gcactcaatg
     9301 gcaatgcgca gacgcgtctg ctgcggttca ttgcaggctt gcagggcctg gctaatttgc
     9361 ggcagtacct ggtttgccag ttgcaacagg atttctccct gcggtgtaaa gcgtagcggc
     9421 tggctcttac gcacaaatag ccggaagcca aggcgttgtt ccagatcgct aaactggtga
     9481 gacagggcgg attgcgtctg atgcaacgtc gccgcagcgg ctgcgagcga gccgcagttc
     9541 cgcaacgctt gtagcgtttt caggtgtttt acttcgatca tgaaagtcct tcacttcggc
     9601 atgaataatt tgcgcttgag gaatatacag taaccgccaa ttatggatgt gtaaacatct
     9661 ggacggctaa aatccttcgt cttttaaatt tatggtgcgt tggctgcgtt tctccacccc
     9721 ggtcacttac ttcagtaagc tcccggggat gaataaactt gccgccttcc ctaaattcaa
     9781 aatccatagg atttacatat aattagagga agaaaaaatg acaatattga atcacaccct
     9841 cggtttccct cgcgttggcc tgcgtcgcga gctgaaaaaa gcgcaagaaa gttattgggc
     9901 ggggaactcc acgcgtgaag aactgctggc ggtagggcgt gaattgcgtg ctcgtcactg
     9961 ggatcaacaa aagcaagcgg gtatcgacct gctgccggtg ggcgattttg cctggtacga
    10021 tcatgtactg accaccagtc tgctgctggg taacgttccg gcgcgtcatc agaacaaaga
    10081 tggttcggta gatatcgaca ccctgttccg tattggtcgt ggacgtgcgc cgactggcga
    10141 acctgcggcg gcagcggaaa tgaccaaatg gtttaacacc aactatcact acatggtgcc
    10201 ggagttcgtt aaaggccaac agttcaaact gacctggacg cagctgctgg acgaagtgga
    10261 cgaggcgctg gcgctgggcc acaaggtgaa acctgtgctg ctggggccgg ttacctggct
    10321 gtggctgggg aaagtgaaag gtgaacaatt tgaccgcctg agcctgctga acgacattct
    10381 gccggtttat cagcaagtgc tggcagaact ggcgaaacgc ggcatcgagt gggtacagat
    10441 tgatgaaccc gcgctggtac tggaactacc acaggcgtgg ctggacgcat acaaacccgc
    10501 ttacgacgcg ctccagggac aggtgaaact gctgctgacc acctattttg aaggcgtaac
    10561 gccaaatctc gacacgatta ctgcgctgcc tgttcagggt ctgcatgttg acctcgtaca
    10621 tggtaaagat gacgttgctg aactgcacaa gcgcctgcct tctgactggt tgctgtctgc
    10681 gggtctgatc aatggtcgta acgtctggcg cgccgatctt accgagaaat atgcgcaaat
    10741 taaggacatt gtcggcaaac gtgatttgtg ggtggcatct tcctgctcgt tgctgcacag
    10801 ccccatcgac ctgagcgtgg aaacgcgtct tgatgcagaa gtgaaaagct ggtttgcctt
    10861 cgccctacaa aaatgccatg aactggcact gctgcgcgat gcgctgaaca gtggtgacac
    10921 ggcagctctg gcagagtgga gcgccccgat tcaggcacgt cgtcactcta cccgcgtaca
    10981 taatccggcg gtagaaaagc gtctggcggc gatcaccgcc caggacagcc agcgtgcgaa
    11041 tgtctatgaa gtgcgtgctg aagcccagcg tgcgcgtttt aaactgccag cgtggccgac
    11101 caccacgatt ggttccttcc cgcaaaccac ggaaattcgt accctgcgtc tggatttcaa
    11161 aaagggcaat ctcgacgcca acaactaccg cacgggcatt gcggaacata tcaagcaggc
    11221 cattgttgag caggaacgtt tgggactgga tgtgctggta catggcgagg ccgagcgtaa
    11281 tgacatggtg gaatactttg gcgagcacct cgacggattt gtctttacgc aaaacggttg
    11341 ggtacagagc tacggttccc gctgcgtgaa gccaccgatt gtcattggtg acattagccg
    11401 cccggcaccg attaccgtgg agtgggcgaa gtatgcgcaa tcgctgaccg acaaaccggt
    11461 gaaagggatg ctgacggggc cggtgaccat actctgctgg tcgttcccgc gtgaagatgt
    11521 cagccgtgaa accatcgcca aacagattgc gctggcgctg cgtgatgaag tggccgatct
    11581 ggaagccgct ggaattggca tcatccagat tgacgaaccg gcgctgcgcg aaggtttacc
    11641 gctgcgtcgt agcgactggg atgcgtatct ccagtggggc gtagaggcct tccgtatcaa
    11701 cgccgccgtg gcgaaagatg acacacaaat ccacactcac atgtgttatt gcgagttcaa
    11761 cgacatcatg gattcgattg cggcgctgga cgcagacgtc atcaccatcg aaacctcgcg
    11821 ttccgacatg gagttgctgg agtcgtttga agagtttgat tatccaaatg aaatcggtcc
    11881 tggcgtctat gacattcact cgccaaacgt accgagcgtg gaatggattg aagccttgct
    11941 gaagaaagcg gcaaaacgca ttccggcaga gcgcctgtgg gtcaacccgg actgtggcct
    12001 gaaaacgcgc ggctggccag aaacccgcgc ggcactggcg aacatggtgc aggcggcgca
    12061 gaatttgcgt cgggggtaaa atccaaaccg ggtggtaata ccacccggtc ttttctcatt
    12121 acagcgactt cttcccacca tactgcttaa accattccag catacgctgc cagccatctt
    12181 tcgcagatgc ggcatgatag ctcgggcgat aatcagcatt gaatgcatgc ccggcatccg
    12241 ggtacacgat aatctctgct ttcgcattag cagcccgcag cgcctggcgc atggtttcaa
    12301 cgctctcctg cggaatactg ttatccagac cgccatataa gccgagaacc ggcgcgttaa
    12361 gatcggttgc gatatcaaca ggttgtttcg gtgaattcag cgacttgtcg cccgtcagtt
    12421 tgccgtacca cgccactgcg gcttttagct gtggattatg cgcggcatac agccaggtga
    12481 tacgtccacc ccagcagaat ccggtgatca ttaaacgatg aacatcgccg ccgttgcggg
    12541 aagcccaact ggcgacatga tcgagatcgg ccagcacctg cgagtcaggc acttttgcta
    12601 ccagaccgct aagcaacgtg gggatatcgg caaaatcatt cggatcgcct tcgcggaagt
    12661 aaagttcagg tgcgatagcc agatacccct ccagcgccag acggcgacaa atgtcgcgga
    12721 tatgttcatg cacgccaaaa atttcctgca ctacaatgac cactggcagt gggccatcgc
    12781 tttgctttgg tctggcatgg taagcaggca tgttatcccc ttgtgaaggg atagaggtga
    12841 agcccgccac aatcgcgtcg tccggggtct gaacgatggt cgaagcgaga ggcgatgcag
    12901 caggtgcaaa tccagattgt tgtgttgttg ccatggtatt ctccgtaccc ttataaaaat
    12961 gttgcgcaat gttaactata gtcagcatgc aacaaatcac attgcctgaa tcggctcatc
    13021 ttttatgcag tcctgcagaa tgaagagtga tttatgtgat ttgaatcact tttggtgggt
    13081 aaatttatgc aacgcatttg cgtcatggtg atgagtatca cgaaaaaatg ttaaaccctt
    13141 cggtaaagtg tctttttgct tcttctgact aaaccgattc acagaggagt tgtatatgtc
    13201 caagtctgat gtttttcatc tcggcctcac taaaaacgat ttacaagggg ctacgcttgc
    13261 catcgtccct ggcgacccgg atcgtgtgga aaagatcgcc gcgctgatgg ataagccggt
    13321 taagctggca tctcaccgcg aattcaccac ctggcgtgca gagctggatg gtaaacctgt
    13381 tatcgtctgc tctaccggta tcggcggccc gtctacctct attgctgttg aagagctggc
    13441 acagctgggc attcgcacct tcctgcgtat cggtacaacg ggcgctattc agccgcatat
    13501 taatgtgggt gatgtcctgg ttaccacggc gtctgtccgt ctggatggcg cgagcctgca
    13561 cttcgcaccg ctggaattcc cggctgtcgc tgatttcgaa tgtacgactg cgctggttga
    13621 agctgcgaaa tccattggcg cgacaactca cgttggcgtg acagcttctt ctgatacctt
    13681 ctacccaggt caggaacgtt acgatactta ctctggtcgc gtagttcgtc actttaaagg
    13741 ttctatggaa gagtggcagg cgatgggcgt aatgaactat gaaatggaat ctgcaaccct
    13801 gctgaccatg tgtgcaagtc agggcctgcg tgccggtatg gtagcgggtg ttatcgttaa
    13861 ccgcacccag caagagatcc cgaatgctga gacgatgaaa caaactgaaa gccaagcggt
    13921 gaaaatcgtg gtggaagcgg cgcgtcgtct gctgtaattc tcttctcctg tctgaaggcc
    13981 gacgcgttcg gccttttgta tttttgcgta gcgcctcgca ggaaatgcct ttccaactgg
    14041 acgtttgtac agcacaattc tattttgtgc gggtaagttg ttgcgtcagg aggcgttgtg
    14101 gatttctcaa tcatggttta cgcagttatt gcgttggtgg gtgtggcaat tggctggctg
    14161 tttgccagtt atcaacatgc gcagcaaaaa gccgagcaat tagctgaacg tgaagagatg
    14221 gtcgcggagt taagcgcggc aaaacaacaa attacccaaa gcgagcactg gcgtgcagag
    14281 tgcgagttac tcaataacga agtgcgcagc ctgcaaagta ttaacacctc tctggaggcc
    14341 gatctgcgtg aagtaaccac gcggatggaa gccgcacagc aacatgctga cgataaaatt
    14401 cgccagatga ttaacagcga gcagcgcctc agtgagcagt ttgaaaacct cgccaaccgt
    14461 atttttgagc acagcaatcg ccgggttgat gagcaaaacc gtcagagtct gaacagcctg
    14521 ttgtcgccgc tacgtgaaca actggacggt ttccgccgtc aggttcagga cagcttcggt
    14581 aaagaagcac aagaacgcca taccctgacc cacgaaattc gcaatctcca gcaactcaac
    14641 gcgcaaatgg cccaggaagc gatcaacctg acgcgcgcgc tgaaaggcga caataaaacc
    14701 cagggcaact ggggcgaggt agtattgacg cgggtgctgg aggcttccgg tctgcgtgaa
    14761 gggtatgaat atgaaaccca ggtcagcatc gaaaatgacg cccgctcgcg gatgcagccg
    14821 gatgtcatcg tgcgcctgcc gcagggaaaa gatgtggtga tcgacgccaa aatgacgctg
    14881 gtcgcctatg aacgctattt taacgccgaa gacgactaca cccgcgaaag cgcgctacag
    14941 gaacatatcg cgtcggtgcg taaccatatc cgtttgctgg gacgcaaaga ttatcaacag
    15001 ctgccggggc tgcgaactct ggattacgtg ctgatgttta ttcccgttga acccgctttt
    15061 ttactggcgc ttgaccgcca gccggagctg atcaccgaag cgttgaaaaa caacatcatg
    15121 ctggttagcc cgactacgct gctggtggcg ctgcgcacta tcgccaacct gtggcgttat
    15181 gagcatcaaa gccgcaacgc ccagcaaatc gccgatcgtg ccagcaagct gtacgacaag
    15241 atgcgtttgt tcatcgatga catgtccgcg attggtcaaa gtctcgacaa agcgcaggat
    15301 aattatcggc aggcaatgaa aaaactctct tcagggcgcg gaaatgtgct ggcgcaggca
    15361 gaagcgtttc gcggtttagg agtagaaatt aaacgcgaga ttaatccgga tttggctgaa
    15421 caggcggtga gccaggatga agagtatcga cttcggtcgg ttccggagca gccgaatgat
    15481 gaagcttatc aacgcgatga tgaatataat cagcagtcgc gctagcccat tgggagtagt
    15541 taagccgggt agaaatctag ggcatcgacg cccaatctgt tacacttctg gaacaatttt
    15601 ttgatgagca ggcattgaga tggtggataa gtcacaagaa acgacgcact ttggttttca
    15661 gaccgtcgcg aaggaacaaa aagcggatat ggtcgcccac gttttccatt ccgtggcatc
    15721 aaaatacgat gtcatgaatg atttgatgtc atttggtatt catcgtttgt ggaagcgatt
    15781 cacgattgat tgcagcggcg tacgccgtgg gcagaccgtg ctggatctgg ctggtggcac
    15841 cggcgacctg acagcgaaat tctcccgcct ggtcggagaa actggcaaag tggtccttgc
    15901 tgatatcaat gaatccatgc tcaaaatggg ccgcgagaag ctgcgtaata tcggtgtgat
    15961 tggcaacgtt gagtatgttc aggcgaacgc tgaggcgctg ccgttcccgg ataacacctt
    16021 tgattgcatc tccatttcgt ttggtctgcg taacgtcacc gacaaagata aagcactgcg
    16081 ttcaatgtat cgcgtgctga aacccggcgg ccgcctgctg gtgcttgagt tctcgaagcc
    16141 aattattgag ccgctgagca aagcctatga tgcatactcc ttccatgtgc tgccgcgtat
    16201 tggctcactg gtcgcgaacg acgccgacag ctaccgttat ctggcagaat ccatccgtat
    16261 gcatcccgat caggataccc tgaaagccat gatgcaggat gccggattcg aaagtgtcga
    16321 ctactacaat ctgacggcag gggttgtggc gctgcatcgt ggttataagt tctgacagga
    16381 gaccggaaat gccttttaaa cctttagtga cggcaggaat tgaaagtctg ctcaacacct
    16441 tcctgtatcg ctcacccgcg ctgaaaacgg cccgctcgcg tctgctgggt aaagtattgc
    16501 gcgtggaggt aaaaggcttt tcgacgtcat tgattctggt gttcagcgaa cgccaggttg
    16561 atgtactggg cgaatgggca ggcgatgctg actgcaccgt tatcgcctac gccagtgtgt
    16621 tgccgaaact tcgcgatcgc cagcagctta ccgcactgat tcgcagtggt gagctggaag
    16681 tgcagggcga tattcaggtg gtgcaaaact tcgttgcgct ggcagatctg gcagagttcg
    16741 accctgcgga actgctggcc ccttataccg gtgatatcgc cgctgaagga atcagcaaag
    16801 ccatgcgcgg aggcgcaaag ttcctgcatc acggcattaa gcgccagcaa cgttatgtgg
    16861 cggaagccat tactgaagag tggcgtatgg cacccggtcc gcttgaagtg gcctggtttg
    16921 cggaagagac ggctgccgtc gagcgtgctg ttgatgccct gaccaaacgg ctggaaaaac
    16981 tggaggctaa atgacgccag gtgaagtacg gcgcctatat ttcatcattc gcactttttt
    17041 aagctacgga cttgatgaac tgatccccaa aatgcgtatc accctgccgc tacggctatg
    17101 gcgatactca ttattctgga tgccaaatcg gcataaagac aaacttttag gtgagcgact
    17161 acgactggcc ctgcaagaac tggggccggt ttggatcaag ttcgggcaaa tgttatcaac
    17221 ccgccgcgat ctttttccac cgcatattgc cgatcagctg gcgttattgc aggacaaagt
    17281 tgctccgttt gatggcaagc tggcgaagca gcagattgaa gctgcaatgg gcggcttgcc
    17341 ggtagaagcg tggtttgacg attttgaaat caagccgctg gcttctgctt ctatcgccca
    17401 ggttcatacc gcgcgattga aatcgaatgg taaagaggtg gtgattaaag tcatccgccc
    17461 ggatattttg ccggtcatta aagcggatct gaaacttatc taccgtctgg ctcgctgggt
    17521 gccgcgtttg ctgccggatg gtcgccgtct gcgcccaacc gaagtggtgc gcgagtacga
    17581 aaagaccttg attgatgaac tgaatttgct gcgggaatct gccaatgcca ttcagcttcg
    17641 gcgcaatttt gaagacagcc cgatgctcta catcccggaa gtttaccctg actattgtag
    17701 tgaagggatg atggtgatgg agcgcattta cggcattccg gtgtctgatg ttgcggcgct
    17761 ggagaaaaac ggcactaaca tgaaattgct ggcggaacgc ggcgtgcagg tgttcttcac
    17821 tcaggttttc cgtgacagct ttttccatgc cgatatgcac cctggcaaca tcttcgtaag
    17881 ctatgaacac ccggaaaacc cgaaatatat cggcattgat tgcgggattg ttggctcgct
    17941 aaacaaagaa gataaacgct atctggcaga aaactttatc gccttcttta atcgcgacta
    18001 tcgcaaagtg gcagagctac acgtcgattc aggctgggtg ccaccagata ccaacgttga
    18061 agagttcgaa tttgccattc gtacggtctg tgaacctatc tttgagaaac cgctggccga
    18121 aatttcgttt ggacatgtac tgttaaatct gtttaatacg gcgcgtcgct tcaatatgga
    18181 agtgcagccg caactggtgt tactccagaa aaccctgctc tatgtcgaag gggtaggacg
    18241 ccagctttat ccgcagctcg atttatggaa aacagcgaag cctttcctgg agtcgtggat
    18301 taaagatcag gtcggtattc ctgcgctggt gagagcattt aaagaaaaag cgccgttctg
    18361 ggtcgaaaaa atgccagaac tgcctgaatt ggtttacgac agtttgcgcc agggcaagta
    18421 tttacagcac agtgttgata agattgcccg cgagcttcag tcaaatcatg tacgtcaggg
    18481 acaatcgcgt tattttctcg gaattggcgc tacgttagta ttaagtggca cattcttgtt
    18541 ggtcagccga cctgaatggg ggctgatgcc cggctggtta atggcaggtg gtctgatcgc
    18601 ctggtttgtc ggttggcgca aaacacgctg attttttcat cgctcaaggc gggccgtgta
    18661 acgtataatg cggctttgtt taatcatcat ctaccacaga ggaacatgta tgggtggtat
    18721 cagtatttgg cagttattga ttattgccgt catcgttgta ctgctttttg gcaccaaaaa
    18781 gctcggctcc atcggttccg atcttggtgc gtcgatcaaa ggctttaaaa aagcaatgag
    18841 cgatgatgaa ccaaagcagg ctaaaaccag tcaggatgct gattttactg cgaaaactat
    18901 cgccgataag caggcggata cgaatcagga acaggctaaa acagaagacg cgaagcgcca
    18961 cgataaagag caggtgtaat ccgtgtttga tatcggtttt agcgaactgc tattggtgtt
    19021 catcatcggc ctcgtcgttc tggggccgca acgactgcct gtggcggtaa aaacggtagc
    19081 gggctggatt cgcgcgttgc gttcactggc gacaacggtg cagaacgaac tgacccagga
    19141 gttaaaactc caggagtttc aggacagtct gaaaaaggtt gaaaaggcga gcctcactaa
    19201 cctgacaccc gaactgaaag cgtcgatgga tgaactacgc caggccgcgg agtcgatgaa
    19261 gcgttcctac gttgcaaacg atcctgaaaa ggcgagcgat gaagcgcaca ccatccataa
    19321 cccggtggtg aaagataatg aagctgcgca tgagggcgta acgcctgccg ctgcacaaac
    19381 gcaggccagt tcgccggaac agaagccaga aaccacgcca gagccggtgg taaaacctgc
    19441 tgcggacgct gaaccgaaaa ccgctgcacc ttccccttcg tcgagtgata aaccgtaaac
    19501 atgtctgtag aagatactca accgcttatc acgcatctga ttgagctgcg taagcgtctg
    19561 ctgaactgca ttatcgcggt gatcgtgata ttcctgtgtc tggtctattt cgccaatgac
    19621 atctatcacc tggtatccgc gccattgatc aagcagttgc cgcaaggttc aacgatgatc
    19681 gccaccgacg tggcctcgcc gttctttacg ccgatcaagc tgacctttat ggtgtcgctg
    19741 attctgtcag cgccggtgat tctctatcag gtgtgggcat ttatcgcccc agcgctgtat
    19801 aagcatgaac gtcgcctggt ggtgccgctg ctggtttcca gctctctgct gttttatatc
    19861 ggcatggcgt tcgcctactt tgtggtcttt ccgctggcat ttggcttcct tgccaatacc
    19921 gcgccggaag gggtgcaggt atccaccgac atcgccagct atttaagctt cgttatggcg
    19981 ctgtttatgg cgtttggtgt ctcctttgaa gtgccggtgg caattgtgct gctgtgctgg
    20041 atggggatta cctcgccaga agacttacgc aaaaaacgcc cgtatgtgct ggttggtgca
    20101 ttcgttgtcg ggatgttgct gacgccgccg gatgtcttct cgcaaacgct gttggcgatc
    20161 ccgatgtact gtctgtttga aatcggtgtc ttcttctcac gcttttacgt tggtaaaggg
    20221 cgaaatcggg aagaggaaaa cgacgctgaa gcagaaagcg aaaaaactga agaataaatt
    20281 caaccgcccg tcagggcggt tgtcatatgg agtacaggat gtttgatatc ggcgttaatt
    20341 tgaccagttc gcaatttgcg aaagaccgtg atgatgttgt agcgcgcgct tttgacgcgg
    20401 gagttaatgg gctactcatc accggcacta acctgcgtga aagccagcag gcgcaaaagc
    20461 tggcgcgtca gtattcgtcc tgttggtcaa cggcgggcgt acatcctcac gacagcagcc
    20521 agtggcaagc tgcgactgaa gaagcgatta ttgagctggc cgcgcagcca gaagtggtgg
    20581 cgattggtga atgtggtctc gactttaacc gcaacttttc gacgccggaa gagcaggaac
    20641 gcgcttttgt tgcccagcta cgcattgccg cagatttaaa catgccggta tttatgcact
    20701 gtcgcgatgc ccacgagcgg tttatgacat tgctggagcc gtggctggat aaactgcctg
    20761 gtgcggttct tcattgcttt accggcacac gcgaagagat gcaggcgtgc gtggcgcatg
    20821 gaatttatat cggcattacc ggttgggttt gcgatgaacg acgcggactg gagctgcggg
    20881 aacttttgcc gttgattccg gcggaaaaat tactgatcga aactgatgcg ccgtatctgc
    20941 tccctcgcga tctcacgcca aagccatcat cccggcgcaa cgagccagcc catctgcccc
    21001 atattttgca acgtattgcg cactggcgtg gagaagatgc cgcatggctg gctgccacca
    21061 cggatgctaa tgtcaaaaca ctgtttggga ttgcgtttta gagtttgcgg aactcggtgt
    21121 tcttcacact gtgcttaatc tctttattaa taagattaag caatagcatg gagcgagcct
    21181 caccatcggg ttcggtgaaa atggcctgaa agccttcgaa cgcgccttcg gtaataatca
    21241 ccttatctcc cggataaggg gttgccggat cgacaatgtc tttcggttta tataccgata
    21301 gctgatgaat caccgccgat gggactatcg ctggcgacgc gccaaagcgc acgaagtgac
    21361 tgacaccgcg ggtcgcgttg atagtcgtgg tatgaatcac ttctggatca aattcgacaa
    21421 acaggtagtt gggaaacaat ggctcactga ctgcagtacg ttttccacgc acgatttttt
    21481 ccagggtgat catcggtgcc aggcaattca cagcctgtct ttcgaggtgt tcctgggcac
    21541 gttgaagttg cccgcgcttg cagtacagta aataccagga ttgcataatg actcttatcc
    21601 gtttaatcgg ggcgcaagga tagcaaaagc tttacgctaa gttaattata ttccccggtt
    21661 tgcgttatac cgtcagagtt cacgctaatt taacaaattt acagcatcgc aaagatgaac
    21721 gccgtataat gggcgcagat taagaggcta caatggacgc catgaaatat aacgatttac
    21781 gcgacttctt gacgctgctt gaacagcagg gtgagctaaa acgtatcacg ctcccggtgg
    21841 atccgcatct ggaaatcact gaaattgctg accgcacttt gcgtgccggt gggcctgcgc
    21901 tgttgttcga aaaccctaaa ggctactcaa tgccggtgct gtgcaacctg ttcggtacgc
    21961 caaagcgcgt ggcgatgggc atggggcagg aagatgtttc ggcgctgcgt gaagttggta
    22021 aattattggc gtttctgaaa gagccggagc cgccaaaagg tttccgcgac ctgtttgata
    22081 aactgccgca gtttaagcaa gtattgaaca tgccgacaaa gcggctgcgt ggtgcgccct
    22141 gccaacaaaa aatcgtctct ggcgatgacg tcgatctcaa tcgcattccc attatgacct
    22201 gctggccgga agatgccgcg ccgctgatta cctgggggct gacagtgacg cgcggcccac
    22261 ataaagagcg gcagaatctg ggcatttatc gccagcagct gattggtaaa aacaaactga
    22321 ttatgcgctg gctgtcgcat cgcggcggcg cgctggatta tcaggagtgg tgtgcggcgc
    22381 atccgggcga acgtttcccg gtttctgtgg cgctgggtgc cgatcccgcc acgattctcg
    22441 gtgcagtcac tcccgttccg gatacgcttt cagagtatgc gtttgccgga ttgctacgtg
    22501 gcaccaagac cgaagtggtg aagtgtatct ccaatgatct tgaagtgccc gccagtgcgg
    22561 agattgtgct ggaagggtat atcgaacaag gcgaaactgc gccggaaggg ccgtatggcg
    22621 accacaccgg ttactataat gaagtcgata gtttcccggt atttaccgtg acgcatatta
    22681 cccagcgtga agatgcgatt taccattcca cctataccgg gcgtccgcca gatgagcccg
    22741 cggtgctggg tgtcgcactg aacgaagtgt ttgtgccgat tctgcaaaaa cagttcccgg
    22801 aaattgtcga tttttacctg ccgccggaag gctgctctta tcgcctggcg gtagtgacaa
    22861 tcaaaaaaca gtacgccgga cacgcgaagc gcgtcatgat gggcgtctgg tcgttcttac
    22921 gccagtttat gtacactaaa tttgtgatcg tttgcgatga tgacgttaac gcacgcgact
    22981 ggaacgatgt gatttgggcg attaccaccc gtatggaccc ggcgcgggat actgttctgg
    23041 tagaaaatac gcctattgat tatctggatt ttgcctcgcc tgtctccggg ctgggttcaa
    23101 aaatggggct ggatgccacg aataaatggc cgggggaaac ccagcgtgaa tggggacgtc
    23161 ccatcaaaaa agatccagat gttgtcgcgc atattgacgc catctgggat gaactggcta
    23221 tttttaacaa cggtaaaagc gcctgatgcg cgtttgtttt gccctattta tcgatccgac
    23281 agagaaagcg catgacaacc ttaagctgta aagtgacctc ggtagaagct atcacggata
    23341 ccgtatatcg tgtccgcatc gtgccagacg cggccttttc ttttcgtgct ggtcagtatt
    23401 tgatggtagt gatggatgag cgcgacaaac gtccgttctc aatggcttcg acgccggatg
    23461 aaaaagggtt tatcgagctg catattggcg cttctgaaat caacctttac gcgaaagcag
    23521 tcatggaccg catcctcaaa gatcatcaaa tcgtggtcga cattccccac ggagaagcgt
    23581 ggctgcgcga tgatgaagag cgtccgatga ttttgattgc gggcggcacc gggttctctt
    23641 atgcccgctc gattttgctg acagcgttgg cgcgtaaccc aaaccgtgat atcaccattt
    23701 actggggcgg gcgtgaagag cagcatctgt atgatctctg cgagcttgag gcgctttcgt
    23761 tgaagcatcc tggtctgcaa gtggtgccgg tggttgaaca accggaagcg ggctggcgtg
    23821 ggcgtactgg caccgtgtta acggcggtat tgcaggatca cggtacgctg gcagagcatg
    23881 atatctatat tgccggacgt tttgagatgg cgaaaattgc ccgcgatctg ttttgcagtg
    23941 agcgtaatgc gcgggaagat cgcctgtttg gcgatgcgtt tgcatttatc tgagatataa
    24001 aaaaacccgc ccctgacagg cgggaagaac ggcaactaaa ctgttattca gtggcattta
    24061 gatctatgac gtatctggca aaccatgccc gatgcgacgc tgtcgcgtct tatcgtgcct
    24121 acaaatagtc cgaaccgtag gccggataag gcgtttacgc cgcatccggc aattggtgca
    24181 tgatgcctga tgcgacgctg gcgcgtctta tcaggcctac attggtgccg gatcggtaga
    24241 ccggataagg cgttcacgcc gcatccggca agtggttaaa cccgctcaaa caccgtcgca
    24301 ataccctgac ccagaccgat acacatcgtc gccagaccaa actgaacgtc tttgcgttcc
    24361 atcagattca gcagcgtggt gctgatacgc gcaccggaac aacccagcgg atgacccagc
    24421 gcgatcgcgc caccgttgag gttgatcttc tcgtcaatct gctcaattag tcccagatct
    24481 ttaatacatg gcaggatctg cgcggcaaag gcttcgttca tttcaaacac gccgatatcg
    24541 ctggcagaaa gccccgcttt tttcagcgcc agtttcgagg ccggaaccgg gccgtaaccc
    24601 ataatcgatg ggtcacaacc aacgaccgcc atcgaacgca cacgagcgcg cggcttaaga
    24661 cctaattcat gggcgcggct ttcactcatc accagcatgg cagctgcgcc atcggaaagt
    24721 gcagaagatg tgcccgccgt taccataccg tttactggat caaacgccgg acgcagcgtg
    24781 gcgagggctt ccacggtggt ttccgggcga atcacttcgt cgtaattaaa ctgcttcagg
    24841 acgccgtcgg catcgtgacc accggtcggg atgatttcat ttttaaatgc ggccgactgc
    24901 gtggcggccc aggcgcgggc gtgtgaccgc gcggcaaagg catcctgcat ttcacggctg
    24961 ataccgtgca tacgcgccag catttctgcc gttaagccca tcatgcccgc cgctttggcg
    25021 acattgcggc tcaggccggg gtgaaaatcg acgccgtgac tcatcggcac atggcccata
    25081 tgctccacgc cgccaaccag acatgcctgc gcatcgccag tcatgatcat tcgtgctgcg
    25141 tcatgcagtg cctgcatgga tgaaccacac aagcgattga cggtaaccgc cgggacagag
    25201 tgcggcactt ctgccagcag cgccgcgtta cgggcgatgt taaaaccctg ctccagcgtc
    25261 tgctgcacac aaccccagta aatatcgtcg agggccgccg cttccagcgc cgggttacgc
    25321 gccagcaggc tacgcattaa atgagcggag agatcttccg cacgcacgtt acgaaaagca
    25381 ccgcccttcg aacggcccat cggggtgcga attgcatcga caatgacaac ctgttccatt
    25441 gtgactcctt aagccgtttt caggtcgcca accggacggg ctggctcaac cggaggatag
    25501 tacggttcgt tatgacgcgc tttattacgc agaccttccg gcacttcata cagcgggccg
    25561 aggtgctgat attgctgtgc catatcgagg tattttgcgc taccgagggt gtccagccag
    25621 cggaacgcgc cgccgtggaa cggagggaag cccaggccgt agaccagcgc catatccgct
    25681 tctgccggag tggcgataat gctttcttcc agacagcgca ccacttcgtt gaccatcggg
    25741 atcatcatgc gggcgataat ctcttcttcg ctgaaatcgc gcttcggctg gctcacttct
    25801 gccagcaggt cgtcaacgac ggcgtcttct tctttcttcg gcttaccttt gctgtcttct
    25861 ttataacgcc agaaaccgag gccgttcttc tgaccaaagc ggttggcatc aaacagcgcg
    25921 tcgatggtat cgcgataatc tttctgcatc cgctgcggga agcctgctgc catgacagcc
    25981 tgggcatgat gcgcggtgtc aatgcccacg acatccagca gatatgccgg acccatcggc
    26041 cagccaaact gtttttccat tactttgtcg atcttgcgga aatccgcgcc gtcgcgcagc
    26101 aactggctga aaccggcgaa atacgggaac agcacgcggt tgacgaagaa gccggggcag
    26161 tcgttaacca caatcggcgt tttgcccatc ttgctcgccc aggcgacgac tttcgcgatg
    26221 gtttcgtcgg agcttttctc gccgcgaata atttccacca acggcattcg gtggaccggg
    26281 ttaaagaagt gcatcccgca gaagttttcc ggacgttcca gcgcgttggc cagttcgctg
    26341 ataggaatgg ttgaagtgtt agacgccagc acggtatccg ggcgtacttt ttgttcggtt
    26401 tctgccagta cggctttttt cactttcgga ttttcgacaa ccgcttctac cacaacatcc
    26461 acgcggtcaa atccggcgta gtcgagcgtt gggtggattg tggagatcac gccagccagt
    26521 ttcagaccat cgatcttgcc gcgctcaagc tgcttgttca gcagtttcgc agcttcggtc
    26581 atgccgaggg ttaacgactt gtcgttgata tctttcatga taaccggcac gcctttccac
    26641 gcagactggt aagcgatgcc gccgcccatg atgcctgcgc ccagcacagc ggcctgtttc
    26701 ggtgtttcaa tgtctttggt gagtttcttc gctttgcctt ttacatattg atcgttaagg
    26761 aaaatgccga ccagtgcgcg ggcttcgttg gtgtgcgcca gcgggacaaa acttttgttt
    26821 tccagattta atgcttcttc acgaccaaaa cgggccgcag cttcaatggt ttttactgcg
    26881 gtgatggggg ccggataatg tttccccgcc gtttgcgcga ctatcccttt agcgatggtg
    26941 aagctcatgg tagcttcaat cttgctcagt tttagcggtt ccagcttcgg ctgacgtttt
    27001 gctttccagt cgaggtcacc gttaatggcc tggcgtaaaa tcgccttcgc gccttcaacc
    27061 agtttttctg ctttgactac gccatccacc agaccgattt tcagcgcctg atccgcgccg
    27121 acatctttac cggcagcaat gatttccagc gcactgtcag cgcccagcat acgtggcata
    27181 cgtacagaac cgccaaagcc cggcatgatg cccagtttgg tttccggcag accgatgcgc
    27241 agatccggcg tcgccagacg ataatcggtc gccagcacgc attcgcagcc accgcccagc
    27301 gcatagccgt tgacggcagc aatggtcggc accggcagat cttccaggcg attaaacacg
    27361 ctattggcaa agtgcagcca ctgacttaac tgttcttcag gaacgaggaa cagggacaaa
    27421 aattcggtga tatcagcacc gacgataaag gctgctttgt tcgaacgcag cagcagccct
    27481 tttagatctg attgctgttc cagcacgccg atggcctcgc cgaggctggc gacggtcgca
    27541 gtgtcgagtt tattaactga acctggggca tcaaatacca gttcggcaat gccatcttcc
    27601 agccagtcaa ggtacagggt gtcgcctttg taaagcatgt cagtctcctg aatccgcaag
    27661 gtgatctggt cgtaccagat gagtcgaagt gtgtattttg tgttaaaaat atgcaaacaa
    27721 aagattaaag aaatgccgat ctgatcacgc tcggcagaaa tcacgctctg gatgaacgat
    27781 gtgctaagat gcggagactt aaggtcaaaa aaacagaagg gtaaaaaatg gaatcactgg
    27841 cctcgctcta taaaaatcat atagctacct tacaagaacg gactcgcgat gcgctggcgc
    27901 gcttcaagct ggatgcgtta cttattcact ccggcgagct gttcaatgtt tttctcgacg
    27961 atcatcccta tccgtttaaa gtgaacccgc aattcaaagc gtgggtgccg gtaactcagg
    28021 tgccaaactg ctggttgctg gtggatggcg tgaataagcc gaaactgtgg ttctatctgc
    28081 cggttgatta ctggcacaac gtcgaaccgc tgccgacctc cttctggact gaagatgtag
    28141 aagtgatcgc gctgccaaaa gccgatggca ttggtagtct gttgcctgct gcgcgcggca
    28201 atatcggtta tatcggtccg gtgccggaac gtgcgctgca actgggtatt gaggccagca
    28261 acatcaaccc gaaaggggtg atcgactacc tgcattacta ccgctccttc aaaaccgagt
    28321 acgaactggc ctgtatgcgt gaagcgcaga aaatggcggt caacggtcat cgtgcggcag
    28381 aagaagcgtt ccgttctggc atgagcgagt tcgatatcaa tattgcctat ctgaccgcga
    28441 ccggtcatcg tgataccgac gtaccttaca gcaacattgt ggcgcttaac gaacacgctg
    28501 cggtgttgca ttacaccaaa ctggaccacc aggcaccgga agagatgcgc agcttcctgc
    28561 tggatgccgg ggccgaatat aacggctatg cggctgacct gacccgtacc tggtcggcaa
    28621 aaagcgacaa cgactacgca cagctggtga aagacgtaaa tgatgaacaa ctggcgctga
    28681 tcgctaccat gaaagcaggc gttagctatg tggattacca catccagttc catcagcgca
    28741 tcgccaaact gctgcgtaaa catcaaatca tcaccgatat gagtgaagaa gcgatggtcg
    28801 aaaacgatct caccggaccg tttatgccgc acggtatcgg ccatccgctg ggcctgcagg
    28861 tgcatgacgt cgccggtttt atgcaggatg atagcggtac gcacctcgcg gcaccggcaa
    28921 aatatccgta cctgcgctgc acccgtattc tccagccggg catggtgtta accattgaac
    28981 cgggtatcta cttcatcgaa tcgctgctgg caccgtggcg tgaagggcag ttcagcaagc
    29041 acttcaactg gcagaaaatt gaagcactga aaccgttcgg cggcattcgt atcgaagaca
    29101 acgtggtgat ccacgaaaat aacgtggaaa acatgacccg ggatctgaaa ctggcgtgat
    29161 ggaaagctgg ttaattcctg cggcaccggt cacggtcgtt gaagagatca aaaaaagccg
    29221 cttcataacg atgttggcgc ataccgatgg cgttgaggcg gcgaaagcgt ttgttgaatc
    29281 ggtgcgggca gaacaccccg atgcccgcca ccattgcgtg gcgtgggtgg cgggtgcgcc
    29341 ggatgattct caacagctgg gtttctctga cgacggggag ccggcgggaa cggcaggtaa
    29401 accgatgctc gcccagctaa tgggcagcgg cgtcggggaa attaccgctg tggtagtgcg
    29461 ctactacggc ggcatattgc ttggcaccgg tgggttagtg aaagcgtatg gcggcggcgt
    29521 gaatcaggcg ctgcgccagc taacgaccca acgcaagacg ccattaaccg aatatacttt
    29581 gcaatgtgaa tatagtcagt taaccggcat tgaagcgttg ctggggcagt gtgacggcaa
    29641 aattatcaac agtgattatc aggcattcgt tctgctgcgg gtggcgcttc cggcggcgaa
    29701 agtggctgaa ttttccgcaa agctggcgga ttttagccgt ggttcattgc aattgttagc
    29761 gattgaagaa taatccccac ttcgttttgc agaactaagg aagcggcaga gatgcatttt
    29821 cgcgccatta cccgaatcgt tggactactg gtcatcttat tttcagggac catgattatc
    29881 cctgggctgg tagcactcat ctaccgggat ggagcgggcc gcgcttttac ccagaccttt
    29941 tttgtcgccc tcgccattgg ctctatgctg tggtggccga accgcaaaga gaagggcgaa
    30001 ctgaaatccc gtgaggggtt tctgatagtg gtgctgttct ggaccgtgct gggtagtgtc
    30061 ggtgcgctcc cttttatctt ctcggaaagc ccgaacctca cgattaccga tgcgtttttt
    30121 gaatctttct ctggcctgac caccaccggg gccactacgc tggtggggct ggattcgctc
    30181 cctcatgcca tcctctttta tcgccagatg ctgcaatggt ttggcgggat ggggatcatc
    30241 gtgttggcgg ttgcgatact gcctatcctc ggcgtgggtg ggatgcagct ctatcgcgca
    30301 gaaatgcccg gcccgctgaa agataacaaa atgcgcccgc gaattgcgga aacggcgaaa
    30361 accctgtggt tgatttatgt cttgctgacc gtcgcctgtg cgctggcgtt gtggtttgcc
    30421 ggaatggatg cctttgatgc catcggccat agctttgcga ctatcgctat tggcggcttc
    30481 tcgacacatg atgccagtat cggttatttc gacagcccga ctattaacac tatcattgct
    30541 atcttcctgc tgatctccgg ctgtaactac ggtctgcact tttcactgtt aagtgggcgt
    30601 agtctgaagg tttattggcg cgatccggaa tttcgcatgt ttatcggcgt acagtttacg
    30661 ctggtggtta tttgtacact cgtactgtgg tttcataatg tctacagttc ggcgctgatg
    30721 acaattaacc aggcgttttt ccaggtggta tcgatggcga caaccgccgg gtttacgact
    30781 gacagcattg cccgctggcc gctctttttg ccggtactgc ttttatgttc agcttttatc
    30841 ggcggttgcg ccgggtcaac gggcggtggc ctgaaagtga tccgcatcct gctgctgttt
    30901 aagcagggga accgtgagct gaaacgactg gtgcatccga acgccgtcta tagcattaag
    30961 ctggggaatc gcgcactgcc ggaacgtatc ctcgaagccg tttggggatt tttctccgcc
    31021 tatgcattgg tgtttattgt cagtatgctg gcgattatcg ccacgggcgt ggatgacttt
    31081 tctgcctttg cctcagttgt tgcgacattg aataacctgg ggccagggct tggcgtggtt
    31141 gctgataact ttaccagtat gaacccggtg gctaaatgga tcctgattgc caacatgctg
    31201 tttggtcgtc ttgaggtctt tacattgctg gtgctcttta ccccgacttt ctggcgtgaa
    31261 tgatggagta atacgtgaaa acattaattc ttttctcaac aagggacgga caaacgcgcg
    31321 agattgcctc ctacctggct tcggaactga aagaactggg gatccagacg gatgtcgcca
    31381 atgtgcaccg cattgaagaa ccacaatggg aaaactatga ccgtgtggtc attggtgctt
    31441 ctattcgcta tggtcactac cactctgcgt tccaggaatt tgtcaaaaaa catgcgacgc
    31501 gactgaattc gatgccgagc gccttttatt ccgtaaacct ggtggcgcgc aaaccggaga
    31561 agcgtactcc acagaccaac agctacgcgc ggaagtttct gatgaactcg caatggcgtc
    31621 ccgatcgctg cgcggtcatt gccggggcgc tgcgttaccc acgttatcgc tggtatgacc
    31681 gttttatgat caagctgatt atgaagatgt caggcggtga aacggatacg cgcaaagaag
    31741 ttgtctatac cgattgggag caggtggcga atttcgcccg agaaatcgcc catttaaccg
    31801 acaaaccgac gctgaaataa gcataaagaa taaaaaatgc gcggtcagaa aattatttta
    31861 aatttcctct tgtcagaccg gaataactcc ctataatgcg ccaccactga cacggaacaa
    31921 cggcaaacac gccgccgggt cagcggggtt ctcctgagaa tctcaacaga gaaaagtaaa
    31981 aaaatgcttg actctgtagc gggaaagcgt attatgcaca ccccgcgccg ctgagaaaaa
    32041 gcgaagcggc actgctcttt aacaatttat cagacaatct gtgtgggcac tcgaagatac
    32101 ggattcttaa cgtcgcaaga cga
//
LOCUS       DAPHKZ010000044        31668 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.044, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000044 DAPHKZ010000000
VERSION     DAPHKZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31668
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.044"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..567
                     /gene="tuf"
                     /locus_tag="RH288_002156"
     CDS             <1..567
                     /gene="tuf"
                     /locus_tag="RH288_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312930.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDV4031205.1"
                     /translation="IDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKE
                     TQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESE
                     VYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHP
                     IAMDDGLRFAIREGGRTVGAGVVAKVLS"
     gene            797..1180
                     /gene="secE"
                     /locus_tag="RH288_002157"
     CDS             797..1180
                     /gene="secE"
                     /locus_tag="RH288_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDV4031206.1"
                     /translation="MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            1182..1727
                     /gene="nusG"
                     /locus_tag="RH288_002158"
     CDS             1182..1727
                     /gene="nusG"
                     /locus_tag="RH288_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDV4031207.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEDLFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1886..2314
                     /gene="rplK"
                     /locus_tag="RH288_002159"
     CDS             1886..2314
                     /gene="rplK"
                     /locus_tag="RH288_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDV4031208.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            2318..3022
                     /gene="rplA"
                     /locus_tag="RH288_002160"
     CDS             2318..3022
                     /gene="rplA"
                     /locus_tag="RH288_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDV4031209.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAD
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASVN"
     gene            3435..3932
                     /gene="rplJ"
                     /locus_tag="RH288_002161"
     CDS             3435..3932
                     /gene="rplJ"
                     /locus_tag="RH288_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDV4031210.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            3999..4364
                     /gene="rplL"
                     /locus_tag="RH288_002162"
     CDS             3999..4364
                     /gene="rplL"
                     /locus_tag="RH288_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDV4031211.1"
                     /translation="MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKALEEAGAEVEVK"
     gene            4684..8712
                     /gene="rpoB"
                     /locus_tag="RH288_002163"
     CDS             4684..8712
                     /gene="rpoB"
                     /locus_tag="RH288_002163"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDV4031212.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     EEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8789..13012
                     /gene="rpoC"
                     /locus_tag="RH288_002164"
     CDS             8789..13012
                     /gene="rpoC"
                     /locus_tag="RH288_002164"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDV4031213.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAK
                     TSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEA
                     PAAPQVTAEDASASLAELLNAGLGGSDNE"
     gene            13225..13764
                     /locus_tag="RH288_002165"
     CDS             13225..13764
                     /locus_tag="RH288_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-shock protein C"
                     /protein_id="HDV4031214.1"
                     /translation="MKQEVEKWRPFGHPDGDIRDLSFLDAHQAVYVQHHEGKEPLEYR
                     FWVTYSLHCFTKDYEHQTNEEKQSLMYHAPKESRPFCQHRYNLARTHLKRTILALPES
                     NVIHAGYGSYAVIEVDLDGGDKAFYFVAFRAFREKKKLRLHVTSAYPISEKQKGKSVK
                     FFTIAYNLLRNKQLPQPSK"
     gene            complement(14174..15307)
                     /gene="thiH"
                     /locus_tag="RH288_002166"
     CDS             complement(14174..15307)
                     /gene="thiH"
                     /locus_tag="RH288_002166"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDV4031215.1"
                     /translation="MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMA
                     LLSPAASGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
                     PLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDNWRVDSYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMD
                     ERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHP
                     ELEQFSPHDDRRPEAVAAALTAQGLQPVWKDWDSYLGRASQRL"
     gene            complement(15304..16074)
                     /gene="thiG"
                     /locus_tag="RH288_002167"
     CDS             complement(15304..16074)
                     /gene="thiG"
                     /locus_tag="RH288_002167"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDV4031216.1"
                     /translation="MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKR
                     VDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDA
                     RWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAK
                     AFRLAVEAGLLARQSGPGSRSYFAHATSPLTGFLEASA"
     gene            complement(16076..16276)
                     /gene="thiS"
                     /locus_tag="RH288_002168"
     CDS             complement(16076..16276)
                     /gene="thiS"
                     /locus_tag="RH288_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDV4031217.1"
                     /translation="MQILFNDQAMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPRE
                     QWAQHIVQDGDQILLFQVIAGG"
     gene            complement(16260..17015)
                     /gene="thiF"
                     /locus_tag="RH288_002169"
     CDS             complement(16260..17015)
                     /gene="thiF"
                     /locus_tag="RH288_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418420.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole biosynthesis adenylyltransferase ThiF"
                     /protein_id="HDV4031218.1"
                     /translation="MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAA
                     LYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTA
                     LQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMV
                     LTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGE
                     LRLFDGKSSQWRSLALRRASGCPVCGGSNADPV"
     gene            complement(17008..17643)
                     /gene="thiE"
                     /locus_tag="RH288_002170"
     CDS             complement(17008..17643)
                     /gene="thiE"
                     /locus_tag="RH288_002170"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709787.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDV4031219.1"
                     /translation="MYQPDFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRR
                     DEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAG
                     LRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYP
                     TVAIGGVSLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE"
     gene            complement(17643..19538)
                     /gene="thiC"
                     /locus_tag="RH288_002171"
     CDS             complement(17643..19538)
                     /gene="thiC"
                     /locus_tag="RH288_002171"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDV4031220.1"
                     /translation="MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRV
                     PMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWID
                     ARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSL
                     GDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
                     LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGVQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEI
                     YLRKEEA"
     regulatory      complement(19619..19719)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(19772..20248)
                     /gene="rsd"
                     /locus_tag="RH288_002172"
     CDS             complement(19772..20248)
                     /gene="rsd"
                     /locus_tag="RH288_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HDV4031221.1"
                     /translation="MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQ
                     IMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA"
     gene            20343..21116
                     /gene="nudC"
                     /locus_tag="RH288_002173"
     CDS             20343..21116
                     /gene="nudC"
                     /locus_tag="RH288_002173"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HDV4031222.1"
                     /translation="MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRAL
                     QIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCG
                     HEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE"
     gene            21156..22220
                     /gene="hemE"
                     /locus_tag="RH288_002174"
     CDS             21156..22220
                     /gene="hemE"
                     /locus_tag="RH288_002174"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HDV4031223.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVP
                     PEHAGVFVEAVHRLSEQYHR"
     gene            22230..22901
                     /gene="nfi"
                     /locus_tag="RH288_002175"
     CDS             22230..22901
                     /gene="nfi"
                     /locus_tag="RH288_002175"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HDV4031224.1"
                     /translation="MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRY
                     TANQP"
     gene            22944..23534
                     /locus_tag="RH288_002176"
     CDS             22944..23534
                     /locus_tag="RH288_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HDV4031225.1"
                     /translation="MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCQQTGFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPSADDFDLYGVYPAIDACVALSE
                     LVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
                     FRLLAECEERDIELIKGLRADLREAGESNIGIIFQQ"
     gene            23721..23993
                     /gene="hupA"
                     /locus_tag="RH288_002177"
     CDS             23721..23993
                     /gene="hupA"
                     /locus_tag="RH288_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HDV4031226.1"
                     /translation="MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            24006..24701
                     /locus_tag="RH288_002178"
     CDS             24006..24701
                     /locus_tag="RH288_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HDV4031227.1"
                     /translation="MNSFNEGVVSPLLSFWRRSLMLAGALLLTACSHNSSLPPFTASG
                     FAEDQGAVRIWRKDSGDNVHLLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKPPV
                     NIRARFDDRGDLSFMQRESDGEKQQLSNDQIDLYRYRADQIRQISDALRQGRVVLRQG
                     RWHAMEQTVTTCEGQTIKPDLDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVAN
                     SDFCRWQPNEKTF"
     gene            complement(24703..25128)
                     /gene="zraP"
                     /locus_tag="RH288_002179"
     CDS             complement(24703..25128)
                     /gene="zraP"
                     /locus_tag="RH288_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HDV4031228.1"
                     /translation="MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQ
                     QTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAANPPDSSKINAVAKEMENLRQSLD
                     ELRVKRDIAMAEAGIPRGAGMGMGYGGCGGGGHMGMGHW"
     gene            25366..26763
                     /gene="zraS"
                     /locus_tag="RH288_002180"
     CDS             25366..26763
                     /gene="zraS"
                     /locus_tag="RH288_002180"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HDV4031229.1"
                     /translation="MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRASEA
                     DRQALLEKGNVLIRALESGSRVGMGMRMHHVQQQALLEEMAGQPGVLWFAVTDAQGII
                     ILHSDPDKVGRALYSPDEMQKLKPEENSRWRLLGKTETTPALEVYRLFQPMSAPWRHG
                     MHNMPRCNGKAVPQVDAQQAIFIAVDASDLVATQSGEKRNTLIILFALATVLLASVLS
                     FFWYRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPA
                     GGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANS
                     REIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKIS
                     VTDSGKGIAADQLDAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGSTF
                     TLWLPVNITRKDPQG"
     gene            26760..28085
                     /gene="zraR"
                     /locus_tag="RH288_002181"
     CDS             26760..28085
                     /gene="zraR"
                     /locus_tag="RH288_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HDV4031230.1"
                     /translation="MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQ
                     VREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALD
                     YLIKPLDFDNLQATLEKALAHTHSIDAETPAVTASQFGMVGKSPAMQHLLSEIALVAP
                     SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQIISVDVR
                     LIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIP
                     LGQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(28082..29371)
                     /gene="purD"
                     /locus_tag="RH288_002182"
     CDS             complement(28082..29371)
                     /gene="purD"
                     /locus_tag="RH288_002182"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDV4031231.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLDFAQNEKIDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLE
                     GSKAFTKDFLARHKIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GDKDTGPNTGGMGAYSPAPVVTDDVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACESKLDEKTSEWDERASLGV
                     VMAAGGYPGDYRTGDVIHGLPLEEVAGGKVFHAGTKLADDEQVVTNGGRVLCVTALGH
                     TVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN"
     gene            complement(29383..30972)
                     /gene="purH"
                     /locus_tag="RH288_002183"
     CDS             complement(29383..30972)
                     /gene="purH"
                     /locus_tag="RH288_002183"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDV4031232.1"
                     /translation="MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLL
                     AEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVV
                     VNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKLDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVK
                     EFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRD
                     LGMVGAEELRVVTKRQPSEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEV
                     IAAADEHGIAMLFTDMRHFRH"
     gene            31587..>31668
                     /locus_tag="RH288_002184"
     rRNA            31587..>31668
                     /locus_tag="RH288_002184"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         7500 a         8185 c         8647 g         7336 t
ORIGIN      
        1 attgacaagc cgttcctgct gccgatcgaa gacgtattct ccatctccgg tcgtggtacc
       61 gttgttaccg gtcgtgtaga acgcggtatc atcaaagttg gtgaagaagt tgaaatcgtt
      121 ggtatcaaag agactcagaa gtctacctgt actggcgttg aaatgttccg caaactgctg
      181 gacgaaggcc gtgctggtga gaacgtaggt gttctgctgc gtggtatcaa acgtgaagaa
      241 atcgaacgtg gtcaggtact ggctaagccg ggcaccatca agccgcacac caagttcgaa
      301 tctgaagtgt acattctgtc caaagatgaa ggcggccgtc atactccgtt cttcaaaggc
      361 taccgtccgc agttctactt ccgtactact gacgtgactg gtaccatcga actgccggaa
      421 ggcgtagaga tggtaatgcc gggcgacaac atcaaaatgg ttgttaccct gatccacccg
      481 atcgcgatgg acgacggtct gcgtttcgca atccgtgaag gcggccgtac cgttggcgcg
      541 ggcgttgtag caaaagttct gagctaattg ccgataacat ttgacgcaat gcgcactaaa
      601 agggcatcat ttgatgccct ttttgcacgc tttcgtacca gaacctggct catcagtgat
      661 tttctttgtc ataatcattg ctgagacagg ctctgttgag ggcgtataat ccgaaaagct
      721 aatacgcgtt tcgatttggt ttgcctcgcg atcgcggggt gaaaatgttt gtagaaaact
      781 tctgacaggt tggtttatga gtgcgaatac cgaagctcaa ggaagcgggc gcggcctgga
      841 agcgatgaag tgggtcgttg tggtggcatt gctcctggtg gcgattgtcg gcaactatct
      901 ttatcgcgac attatgctgc cgctgcgtgc gctggccgta gtaattctga ttgctgcagc
      961 gggtggtgtc gcgctgttaa cgacaaaagg taaagctacc gttgcttttg cccgtgaagc
     1021 gcgtaccgaa gtccgtaagg tcatttggcc gactcgccag gaaacattgc acaccacgct
     1081 gattgtggct gcggttaccg cagtaatgtc actgatcctg tggggactgg atggtattct
     1141 ggttcgcctg gtatccttta tcactggcct gaggttctga gatgtctgaa gctcctaaaa
     1201 agcgctggta cgtcgttcag gcgttttccg gttttgaagg ccgcgtagca acgtcgctgc
     1261 gtgagcatat caaattacac aacatggaag atttgtttgg tgaagtcatg gtaccaaccg
     1321 aagaagtggt tgaaatccgt ggcggtcagc gtcgcaaaag cgaacgtaaa ttcttccctg
     1381 gctacgtcct cgttcagatg gtgatgaacg acgcgagctg gcacctggtg cgcagcgtac
     1441 cgcgtgtgat gggcttcatc ggcggtactt ccgatcgtcc tgcgccaatc agcgataaag
     1501 aagtcgatgc gattatgaac cgcctgcagc aggttggtga taagccgcgt ccgaaaacgc
     1561 tgtttgaacc gggtgaaatg gtccgtgtta atgatggtcc gttcgctgac ttcaacggtg
     1621 ttgttgaaga agtggattac gagaaatctc gtctgaaagt gtctgtttct atcttcggtc
     1681 gtgcgacccc ggtagagctg gacttcagcc aggttgaaaa agcctaaccc agcgatcaaa
     1741 aaagcggcga tttaatcgtt gcacaaggcg tgagattgga atacaatttc gcgccttttg
     1801 tttttatggg ccttgcccgt aaaacgattt tttatatcac ggggagcctc tcagaggcgt
     1861 tattacccaa cttgaggaat ttataatggc taagaaagta caagcctatg tcaagctgca
     1921 ggttgcagct ggtatggcta acccgagtcc gccagtaggt ccggctctgg gtcagcaggg
     1981 cgtaaacatc atggaattct gcaaagcgtt caacgcaaaa actgattcca tcgaaaaagg
     2041 tctgccgatt ccggtagtaa tcaccgttta cgctgaccgt tctttcactt tcgttaccaa
     2101 gaccccgccg gcagcagttc tgctgaaaaa agcggctggt atcaagtctg gttccggtaa
     2161 gccgaacaaa gacaaagtgg gtaaaatttc ccgcgctcag ctgcaggaaa tcgcgcagac
     2221 caaagctgcc gacatgactg gtgccgacat tgaagcgatg actcgctcca tcgaaggtac
     2281 tgcacgttcc atgggcctgg tagtggagga ctaagaaatg gctaaactga ccaagcgcat
     2341 gcgtgttatc cgcgagaaag ttgatgcaac caaacagtac gacatcaacg aagctatcgc
     2401 actgctgaaa gagctggcga ctgctaaatt cgtagaaagc gtggacgtag ctgttaacct
     2461 cggcatcgac gctcgtaaat ctgaccagaa cgtacgtggt gcaactgtac tgccgcacgg
     2521 tactggccgt tccgttcgcg tagccgtatt tacccaaggt gcaaacgctg aagctgctaa
     2581 agctgcaggc gcagaactgg taggtatgga agatctggct gaccagatca agaaaggcga
     2641 aatgaacttt gacgttgtta ttgcttctcc ggatgcaatg cgcgttgttg gccagctggg
     2701 ccaggttctg ggtccgcgcg gcctgatgcc aaacccgaaa gtgggtactg taacaccgaa
     2761 cgttgctgaa gcggttaaaa acgctaaagc tggccaggtt cgttaccgta acgacaaaaa
     2821 cggcatcatc cacaccacca tcggtaaagt ggactttgac gctgacaaac tgaaagaaaa
     2881 cctggaagct ctgctggttg cgctgaaaaa agcaaaaccg actcaggcga aaggcgtgta
     2941 catcaagaaa gttagcatct ccaccaccat gggtgcaggt gttgcagttg accaggctgg
     3001 cctgagcgct tctgtaaact aatgccttta cgtgggcggt gattttgtct acaatcttac
     3061 ccccacgtat aatgcttaat gcagacgtat atccgagata ttcgggttgt ggcaaggcgg
     3121 caactgagtg agtcgccagg agcatagcta actatgtgac tggtgcgaat gaaggaagcc
     3181 aacgccgtca caagctgaat agcgacggat agaaaagatt tgttcgttgg agcctggcct
     3241 atccaggcct ccgtcgaaga ccgcaggagt ttcgcaagaa acttaatccc ctgcgtagac
     3301 ggtgacagaa cgctaagatt attcttttat attctggctt gtttctgctc accgtaatta
     3361 agacgctctc tccgtttgga ggagtgaagt gagttccaga gattttctct ggcaaacatc
     3421 caggagcaaa gctaatggct ttaaatcttc aagacaaaca agcgattgtt gctgaagtca
     3481 gcgaagtagc caaaggcgcg ctgtctgcag tagttgcgga ttcccgtggc gtaactgtag
     3541 ataaaatgac tgaactgcgt aaagcaggtc gcgaagctgg cgtatacatg cgtgttgttc
     3601 gtaacaccct gctgcgccgt gctgttgaag gtactccgtt cgagtgcctg aaagacgcgt
     3661 ttgttggtcc gaccctgatt gcatactcta tggaacaccc gggcgctgct gctcgtctgt
     3721 tcaaagagtt cgcgaaagcg aatgcaaaat ttgaggtcaa agccgctgcc tttgaaggtg
     3781 agctgatccc ggcgtctcag atcgaccgcc tggcaactct gccgacctac gaagaagcaa
     3841 ttgcacgcct gatggcaacc atgaaagaag cttcggctgg caaactggtt cgtactctgg
     3901 ctgctgtacg cgatgcgaaa gaagctgctt aatcgcagtt atctttttaa cgcattcgct
     3961 tacgtataaa cttattctga tattcaggaa caatttaaat gtctatcact aaagatcaaa
     4021 tcattgaagc agttgcagct atgtctgtaa tggacgttgt agaactgatc tctgcaatgg
     4081 aagaaaaatt cggtgtttcc gctgctgctg ctgtagctgt agctgctggc ccggttgaag
     4141 ctgctgaaga aaaaactgaa ttcgacgtaa ttctgaaagc tgctggcgct aacaaagttg
     4201 ctgttatcaa agcagtacgt ggcgcaactg gcctgggtct gaaagaagct aaagacctgg
     4261 tagaatctgc accggctgct ctgaaagaag gcgtgagcaa agacgacgca gaagcactga
     4321 aaaaagctct ggaagaagct ggcgctgaag ttgaagttaa ataagccaac ccttccggtt
     4381 gcagcctgag aaatcaggct gatggctggt gactttttag tcaccagcct ttttgcgctg
     4441 taaggcgcca gtagcgtttc acactgtttg actactgctg tgcctttcaa tgcttgtttc
     4501 tatcgacgac ttaatatact gcgacaggac gtccgttctg tgtaaatcgc aatgaaatgg
     4561 tttaagcgtg atagcaacag gcattgcgga aagtgttcca ttttccggtc aacaaaatag
     4621 tgttgcacaa actgtccgct caatggacag atgggtcgac ttgtcagcga gctgaggaac
     4681 cctatggttt actcctatac cgagaaaaaa cgtattcgta aggattttgg taaacgtcca
     4741 caagttctgg atgtacctta tctcctttct atccagcttg actcgtttca gaaatttatc
     4801 gagcaagatc ctgaagggca gtatggtctg gaagctgctt tccgttccgt attcccgatt
     4861 cagagctaca gcggtaattc cgagctgcaa tacgtcagct accgccttgg cgaaccggtg
     4921 tttgacgtcc aggaatgtca aatccgtggc gtgacctatt ccgcaccgct gcgcgttaaa
     4981 ctgcgtctgg tgatctatga gcgcgaagcg ccggaaggca ccgtaaaaga cattaaagaa
     5041 caagaagtct acatgggcga aattccgctc atgacagaca acggtacctt tgttatcaac
     5101 ggtactgagc gtgttatcgt ttcccagctg caccgtagtc cgggcgtctt ctttgactcc
     5161 gacaaaggta aaacccactc ttcgggtaaa gtgctgtata acgcgcgtat catcccttac
     5221 cgtggttcct ggctggactt cgaattcgat ccgaaggaca acctgttcgt acgtatcgac
     5281 cgtcgccgta aactgcctgc gaccatcatt ctgcgcgccc tgaactacac cacagagcag
     5341 atcctcgacc tgttctttga aaaagttatc tttgaaatcc gtgataacaa gctgcagatg
     5401 gaactggtgc cggaacgcct gcgtggtgaa accgcatctt ttgacatcga agctaacggt
     5461 aaagtgtacg tagaaaaagg ccgccgtatc actgcgcgcc acattcgcca gctggaaaaa
     5521 gacgacgtca aactgatcga agtcccggtt gagtacatcg caggtaaagt ggttgctaaa
     5581 gactatattg atgagtctac cggcgagctg atctgcgcag cgaacatgga gctgagcctg
     5641 gatctgctgg ctaagctgag ccagtctggt cacaagcgta tcgaaacgct gttcaccaac
     5701 gatctggatc acggcccata tatctctgaa accttacgtg tcgacccaac taacgaccgt
     5761 ctgagcgcac tggtagaaat ctaccgcatg atgcgccctg gcgagccgcc gactcgtgaa
     5821 gcagctgaaa gcctgttcga gaacctgttc ttctccgaag accgttatga cttgtctgcg
     5881 gttggtcgta tgaagttcaa ccgttctctg ctgcgcgaag aaatcgaagg ttccggtatc
     5941 ctgagcaaag acgacatcat tgatgttatg aaaaagctca tcgatatccg taacggtaaa
     6001 ggcgaagtcg atgatatcga ccacctcggc aaccgtcgta tccgttccgt tggcgaaatg
     6061 gcggaaaacc agttccgcgt tggcctggta cgtgtagagc gtgcggtgaa agagcgtctg
     6121 tctctgggcg atctggatac cctgatgcca caggatatga tcaacgccaa gccgatttcc
     6181 gcagcagtga aagagttctt cggttccagc cagctgtctc agtttatgga ccagaacaac
     6241 ccgctgtctg agattacgca caaacgtcgt atctccgcac tcggcccagg cggtctgacc
     6301 cgtgaacgtg caggcttcga agttcgagac gtacacccga ctcactacgg tcgcgtatgt
     6361 ccaatcgaaa cccctgaagg tccgaacatc ggtctgatca actctctgtc cgtgtacgca
     6421 cagactaacg aatacggctt ccttgagact ccgtatcgta aagtgaccga cggtgttgta
     6481 actgacgaaa ttcactacct gtctgctatc gaagaaggca actacgttat cgcccaggcg
     6541 aactccaact tggatgaaga aggccacttc gtagaagacc tggtaacttg ccgtagcaaa
     6601 ggcgaatcca gcttgttcag ccgcgaccag gttgactaca tggacgtatc cacccagcag
     6661 gtggtatccg tcggtgcgtc cctgatcccg ttcctagaac acgatgacgc caaccgtgca
     6721 ttgatgggtg cgaacatgca acgtcaggcc gttccgactc tgcgcgctga taagccgctg
     6781 gttggtactg gtatggaacg tgctgttgcc gttgactccg gtgtaactgc ggtagctaaa
     6841 cgtggtggtg tcgttcagta cgtggatgct tcccgtatcg ttatcaaagt taacgaagac
     6901 gagatgtatc cgggtgaagc aggtatcgac atctacaacc tgaccaaata cacccgttct
     6961 aaccagaaca cctgtatcaa ccagatgccg tgtgtgtctc tgggtgaacc ggttgaacgt
     7021 ggcgacgtgc tggcagacgg tccgtccacc gacctcggtg aactggcgct tggtcagaac
     7081 atgcgcgtag cgttcatgcc gtggaatggt tacaacttcg aagactccat cctcgtatcc
     7141 gagcgtgttg ttcaggaaga ccgtttcacc accatccaca ttcaggaact ggcgtgtgtg
     7201 tcccgtgaca ccaagctggg tccggaagag atcaccgctg acatcccgaa cgtgggtgaa
     7261 gctgcgctct ccaaactgga tgaatccggt atcgtttaca ttggtgcgga agtgaccggt
     7321 ggcgacattc tggttggtaa ggtaacgccg aaaggtgaaa ctcagctgac cccagaagaa
     7381 aaactgctgc gtgcgatctt cggtgagaaa gcctctgacg ttaaagactc ttctctgcgc
     7441 gtaccaaacg gtgtatccgg tacggttatc gacgttcagg tctttactcg cgatggcgta
     7501 gaaaaagaca aacgtgcgct ggaaatcgaa gaaatgcagc tcaaacaggc gaagaaagac
     7561 ctgtctgaag aactgcagat cctcgaagcg ggtctgttca gccgtatccg tgctgtgctg
     7621 gtagccggtg gcgttgaagc tgagaagctc gacaaactgc cgcgcgatcg ctggctggag
     7681 ctgggcctga cagacgaaga gaaacaaaat cagctggaac agctggctga gcagtatgac
     7741 gaactgaaac acgagttcga gaagaaactc gaagcgaaac gccgcaaaat cacccagggc
     7801 gacgatctgg caccgggcgt gctgaagatt gttaaggtat atctggcggt taaacgccgt
     7861 atccagcctg gtgacaagat ggcaggtcgt cacggtaaca agggtgtaat ttctaagatc
     7921 aacccgatcg aagatatgcc ttacgatgaa aacggtacgc cggtagacat cgtactgaac
     7981 ccgctgggcg taccgtctcg tatgaacatc ggtcagatcc tcgaaaccca cctgggtatg
     8041 gctgcgaaag gtatcggcga caagatcaac gccatgctga aacagcagca agaagtcgcg
     8101 aaactgcgcg aattcatcca gcgtgcgtac gatctgggcg ctgacgttcg tcagaaagtt
     8161 gacctgagta ccttcagcga tgaagaagtt atgcgtctgg ctgaaaacct gcgcaaaggt
     8221 atgccaatcg caacgccggt gttcgacggt gcgaaagaag cagaaattaa agagctgctg
     8281 aaacttggcg acctgccgac ttccggtcag atccgcctgt acgatggtcg cactggtgaa
     8341 cagttcgagc gtccggtaac cgttggttac atgtacatgc tgaaactgaa ccacctggtc
     8401 gacgacaaga tgcacgcgcg ttccaccggt tcttacagcc tggttactca gcagccgctg
     8461 ggtggtaagg cacagttcgg tggtcagcgt ttcggggaga tggaagtgtg ggcgctggaa
     8521 gcatacggcg cagcatacac cctgcaggaa atgctcaccg ttaagtctga tgacgtgaac
     8581 ggtcgtacca agatgtataa aaacatcgtg gacggcaacc atcagatgga gccgggcatg
     8641 ccagaatcct tcaacgtatt gttgaaagag attcgttcgc tgggtatcaa catcgaactg
     8701 gaagacgagt aattctcgct caaacaggtc actgctgtcg ggttaaaacc cggcagcgga
     8761 ttgtgctaac tccgacggga gcaaatccgt gaaagattta ttaaagtttc tgaaagcgca
     8821 gactaaaacc gaagagtttg atgcgatcaa aattgctctg gcttcgccag acatgatccg
     8881 ttcatggtct ttcggtgaag ttaaaaagcc ggaaaccatc aactaccgta cgttcaaacc
     8941 agaacgtgac ggccttttct gcgcccgtat ctttgggccg gtaaaagatt acgagtgcct
     9001 gtgcggtaag tacaagcgcc tgaaacaccg tggcgtcatc tgtgagaagt gcggcgttga
     9061 agtgacccag actaaagtac gccgtgagcg tatgggccac atcgaactgg cttccccgac
     9121 tgcgcacatc tggttcctga aatcgctgcc gtcccgtatc ggtctgctgc tcgatatgcc
     9181 gctgcgcgat atcgaacgcg tactgtactt tgaatcctat gtggttatcg aaggcggtat
     9241 gaccaacctg gaacgtcagc agatcctgac tgaagagcag tatctggacg cgctggaaga
     9301 gttcggtgac gaattcgacg cgaagatggg ggcggaagca atccaggctc tgctgaagag
     9361 catggatctg gagcaagagt gcgaacagct gcgtgaagag ctgaacgaaa ccaactccga
     9421 aaccaagcgt aaaaagctga ccaagcgtat caaactgctg gaagcgttcg ttcagtctgg
     9481 taacaaacca gagtggatga tcctgaccgt tctgccggta ctgccgccag atctgcgtcc
     9541 gctggttccg ctggatggtg gtcgtttcgc gacttctgac ctgaacgatc tgtatcgtcg
     9601 cgtcattaac cgtaacaacc gtctgaaacg tctgctggat ctggctgcgc cggacatcat
     9661 cgtacgtaac gaaaaacgta tgctgcagga agcggtagac gccctgctgg ataacggtcg
     9721 tcgcggtcgt gcgatcaccg gttctaacaa gcgtcctctg aaatctttgg ccgacatgat
     9781 caaaggtaaa cagggtcgtt tccgtcagaa cctgctcggt aagcgtgttg actactccgg
     9841 tcgttctgta atcaccgtag gtccatacct gcgtctgcat cagtgcggtc tgccgaagaa
     9901 aatggcactg gagctgttca aaccgttcat ctacggcaag ctggaactgc gtggtcttgc
     9961 taccaccatt aaagctgcga agaaaatggt tgagcgcgaa gaagctgtcg tttgggatat
    10021 cctggacgaa gttatccgcg aacacccggt actgctgaac cgtgcaccga ctctgcaccg
    10081 tctgggtatc caggcatttg aaccggtact gatcgaaggt aaagctatcc agctgcaccc
    10141 gctggtttgt gcggcatata acgccgactt cgatggtgac cagatggctg ttcacgtacc
    10201 gctgacgctg gaagcccagc tggaagcgcg tgcgctgatg atgtctacca acaacatcct
    10261 gtccccggcg aacggcgaac caatcatcgt tccgtctcag gacgttgtac tgggtctgta
    10321 ctacatgacc cgtgactgtg ttaacgccaa aggcgaaggc atggtgctga ctggcccgaa
    10381 agaagcagaa cgtctgtatc gctctggtct ggcttctctg catgcgcgcg ttaaagtgcg
    10441 tatcaccgag tatgaaaaag atgctaacgg tgaattagta gcgaaaacca gcctgaaaga
    10501 cacgactgtt ggccgtgcca ttctgtggat gattgtaccg aaaggtctgc cttactccat
    10561 cgtcaaccag gcgctgggta aaaaagcaat ctccaaaatg ctgaacacct gctaccgcat
    10621 tctcggtctg aaaccgaccg ttatttttgc ggaccagatc atgtacaccg gcttcgccta
    10681 tgcagcgcgt tctggtgcat ctgttggtat cgatgacatg gtcatcccgg agaagaaaca
    10741 cgaaatcatc tccgaggcag aagcagaagt tgctgaaatt caggagcagt tccagtctgg
    10801 tctggtaact gcgggcgaac gctacaacaa agttatcgat atctgggctg cggcgaacga
    10861 tcgtgtatcc aaagcgatga tggataacct gcaaactgaa accgtgatta accgtgacgg
    10921 tcaggaagag aagcaggttt ccttcaacag catctacatg atggccgact ccggtgcgcg
    10981 tggttctgcg gcacagattc gtcagcttgc tggtatgcgt ggtctgatgg cgaagccgga
    11041 tggctccatc atcgaaacgc caatcaccgc gaacttccgt gaaggtctga acgtactcca
    11101 gtacttcatc tccacccacg gtgctcgtaa aggtctggcg gataccgcac tgaaaactgc
    11161 gaactccggt tacctgactc gtcgtctggt tgacgtggcg caggacctgg tggttaccga
    11221 agacgattgt ggtacccatg aaggtatcat gatgactccg gttatcgagg gtggtgacgt
    11281 taaagagccg ctgcgcgatc gcgtactggg tcgtgtaact gctgaagacg ttctgaagcc
    11341 gggtactgct gatatcctcg ttccgcgcaa cacgctgctg cacgaacagt ggtgtgacct
    11401 gctggaagag aactctgtcg acgcggttaa agtacgttct gttgtatctt gtgacaccga
    11461 ctttggtgta tgtgcgcact gctacggtcg tgacctggcg cgtggccaca tcatcaacaa
    11521 gggtgaagca atcggtgtta tcgcggcaca gtccatcggt gaaccgggta cacagctgac
    11581 catgcgtacg ttccacatcg gtggtgcggc atctcgtgcg gctgctgaat ccagcatcca
    11641 agtgaaaaac aaaggtagca tcaagctcag caacgtgaag tcggttgtga actccagcgg
    11701 taaactggtt atcacttccc gtaatactga actgaaactg atcgacgaat tcggtcgtac
    11761 taaagaaagc tacaaagtac cttacggtgc ggtactggcg aaaggcgatg gcgaacaggt
    11821 tgctggcggc gaaaccgttg caaactggga cccgcacacc atgccggtta tcaccgaagt
    11881 aagcggtttt gtacgcttta ctgacatgat cgacggccag accattacgc gtcagaccga
    11941 cgaactgacc ggtctgtctt cgctggtggt tctggattcc gcagaacgta ccgcaggtgg
    12001 taaagatctg cgtccggcac tgaaaatcgt tgatgctcag ggtaacgacg ttctgatccc
    12061 aggtaccgat atgccagcgc agtacttcct gccgggtaaa gcgattgttc agctggaaga
    12121 tggcgtacag atcagctctg gtgacaccct ggcgcgtatt ccgcaggaat ccggcggtac
    12181 caaggacatc accggtggtc tgccgcgcgt tgcggacctg ttcgaagcac gtcgtccgaa
    12241 agagccggca atcctggctg aaatcagcgg tatcgtttcc ttcggtaaag aaaccaaagg
    12301 taaacgtcgt ctggttatca ccccggtaga cggtagcgat ccgtacgaag agatgattcc
    12361 gaaatggcgt cagctcaacg tgttcgaagg tgaacgtgta gaacgtggtg acgtaatttc
    12421 cgacggtccg gaagcgccgc acgacattct gcgtctgcgt ggtgttcatg ctgttactcg
    12481 ttacatcgtt aacgaagtac aggacgtata ccgtctgcag ggcgttaaga ttaacgataa
    12541 acacatcgaa gttatcgttc gtcagatgct gcgtaaagct accatcgtta acgcgggtag
    12601 ctccgacttc ctggaaggcg aacaggttga atactctcgc gtcaagatcg caaaccgcga
    12661 actggaagcg aacggcaaag tgggtgcaac ttactcccgc gatctgctgg gtatcaccaa
    12721 agcgtctctg gcaaccgagt ccttcatctc cgcggcatcg ttccaggaga ccactcgcgt
    12781 gctgaccgaa gcagccgttg cgggcaaacg cgacgaactg cgcggcctga aagagaacgt
    12841 tatcgtgggt cgtctgatcc cggcaggtac cggttacgcg taccaccagg atcgtatgcg
    12901 tcgccgtgct gcgggtgaag ctccggctgc accgcaggtg actgcagaag acgcatctgc
    12961 cagcctggca gaactgctga acgcaggtct gggcggttct gataacgagt aatcgttaat
    13021 ccgcaaataa cgtaaaaacc cgcttcggcg ggttttttta tggggggagt ttagggaaag
    13081 agcatttgtc agaatattta aggaatttct gaatactcat aatcaatgta gagatgacta
    13141 atatcctgaa actgactgaa ctaattgagt caaactcggc aaggattcga tactattcct
    13201 gtgtaacttt cttaaggaac gagaatgaaa caggaagtgg aaaagtggcg accttttgga
    13261 catccggatg gtgatattcg tgatttatca tttcttgatg ctcatcaggc tgtctacgtt
    13321 cagcatcatg agggcaaaga gcctttagag tatcgctttt gggttaccta ctctcttcac
    13381 tgcttcacaa aagattatga acatcagacg aacgaagaaa aacaatcgtt aatgtaccac
    13441 gcgcctaaag aatctcgtcc cttctgccag caccgttata acttagcgcg cacacactta
    13501 aaaagaacta ttttggcgct gccagaaagc aacgttattc atgccgggta tggtagctat
    13561 gccgtgattg aggtggactt agacggagga gataaggcat tttactttgt tgcgttcagg
    13621 gctttcaggg aaaagaaaaa actccgtttg catgtaacta gcgcttatcc catttctgaa
    13681 aaacagaaag gtaaatcagt gaaatttttc accattgcct acaacttatt gagaaataag
    13741 cagcttcctc agccctcaaa ataacaaaac ccaccttaag gtgggtttcg ccagagaatt
    13801 atctctggta ttcagaacgc cattaccgga ctttgccttg accttgcgat aatcgcaggt
    13861 tgcgggatgt ctgaatttct tcagtctgct gcatcctgga agatgagaac atgtgttctt
    13921 attttcgtct ctatcatagt tgagtattta ctctcttaca atcagatctc tttcattgct
    13981 caacaggcga tggcttcaga ctttgcatta cggaattttt aagaaaggca gggcgaaacg
    14041 aggaagaagc ttttcgccct ggacaacatt cctgctgacg gcactaccat aaaaaaacac
    14101 aacgctttca acaaccttgc gtttttcatc ttccgtagcg gctcggaata aatttacgtt
    14161 cttacattcc gtctcatagt ctttgcgagg cgcgtcccag atagctgtcc cagtctttcc
    14221 ataccggctg caaaccctga gcggttaacg cggcagcaac cgcttccggt ctgcgatcgt
    14281 cgtgcggtga gaactgttcc aactcggggt gattatcggc atagccacct ggctgcgttt
    14341 tcgagaaggc gctgacgtta ttgatcgcca gcggaataac gcgatcgcga aaccacggtg
    14401 attcccgcgt ggagagtgac agttcaatct ccggtgcaag cagtcggaag gcgcagatgg
    14461 tttgcactaa ctggcgttca tccataatcg acgcaggctc aatgccgcca gtacacgggc
    14521 gcaggcgcgg aaaggagaca gagtaacggc tttgccagta atgctgttgc agccatagca
    14581 aatgttcggc aaccatatag ctgtcaacgc gccagttgtc ggaaaggcca attagcgcgc
    14641 cgaggcctat cttatcaatc cccgcacgcc ccagccgatc cggcgtttcc agccgccaga
    14701 agaagtcctg ttttttgcct ttcagatgat ggcgggcata agtcgcctcg tgatatgtct
    14761 cctgataaac catcacgcca tccagaccaa gttgctttaa ctcggcgtat tccgtctccg
    14821 ccagcggttg cacttccatc tgtagtgaag agaactgttc acgaagggca gggagatgac
    14881 gacgaaagta atccatcccc actttcgcct gatgttcacc agtgactaac agcagatgtt
    14941 caaagcccat ctcccgtata gcggcacttt ccctggcaat atccgcttca tccagcgttt
    15001 tgcgcttgat gcgattactc atggaaaatc cacagtacgt gcagtcgtta gcgcaaagat
    15061 tggaaagata aagcgggacg tagaaactaa ctgtgttgcc aaatcgctga cgggtcagac
    15121 gctgcgcccg ttgggccagt tgttccagat agccactggc ggcaggcgat aacagcgcca
    15181 tcatgtcgtc gcgggtgagt tgcgaggcat ttagcgcccg ctctacgtca gcagccgttt
    15241 tgccgttgat acgcaggcgg atgtcgtccc agtccagttg tcgccagcga tcgctgaagg
    15301 ttttcatgcc gatgcctcca gaaatccggt cagcgggctg gtggcatgag caaaataact
    15361 gcggctgccc ggtccggact gacgtgccag taggcctgct tctaccgcca gacgaaatgc
    15421 cttcgccatg ttgacgggat cgtccgcgac ggcaatcgcc gtattcacta acaccgcgtc
    15481 ggcccccatt tccagcgcct gcgcggcatg gctgggaacg ccgatgccag catcgacaac
    15541 caccggcact gtggcctgct ggataataat ctccagcatg gcgcgggttt ccagtccctg
    15601 attcgagcca atcggcgcgc cgagcggcat caccgctgca cagccgactt cttccagacg
    15661 tttacacaat accggatcgg ccccgcagta aggcagcacg acaaatccct gttgtaccag
    15721 cgtttcggcg gctttcaggg tttcgatggg atcgggcaac agccagcggg cgtcagggtg
    15781 aatctctaat tttaaccagt ttgtgcctaa cgcttcacga gccagatggg cggcgaaaat
    15841 ggcttcttcc gctgttttcg ccccggatgt atttggcagc agggtcacac ccgccgcgat
    15901 aagcggttcg aggatagcgt cgttgtgctg gcgcaagtcg acacgtttca tcgccagtgt
    15961 caccagctgg ctgccggaag cgcggatcgc ctccaccatc agttgtgaag aagcgaattt
    16021 ccctgtgccg gtaaacagat gtgaatcaaa cgttttgtcc gcaatacgta acatttcaac
    16081 cccctgcaat aacctgaaaa agcaggatct ggtcgccatc ctgcacgata tgttgcgccc
    16141 actgctcacg cgggacgatt tgctgattaa tcgccagagc cgcgcccgct tgtcgttggt
    16201 cgagttgctc cagtagttcg tgaacagttt gcccggcggc gcactgcatc gcttgatcgt
    16261 taaacaggat ctgcattgct tcctccgcat accgggcaac cactggcgcg gcgcaacgcc
    16321 aggctgcgcc actggctcga tttaccgtcg aacagtcgga gttctcccgc aggtgtctct
    16381 ataccgctta ataacttaat ggcttccagt gcctgcaaag tgcccataac cccgaccacc
    16441 gggccaacca cgcccgccgt gcggcagttg cgttctggct cctggttatc tggccacagg
    16501 cagcggtaac acccctgctc ccagggcggc gtcagtacca tcaactgacc gccaaatccg
    16561 accgcgctgg cggtgataag cggcgtgttg agtgccacgc aggcggcatt aatctcctgg
    16621 cgagtcgcca tattgtcggt acagtcgagc accacatcgg cccgtgcaac cgcatctttt
    16681 aacgcctcac ccgttaaccg ttgttgtaat gctgtcagtt gaatgtcggg attcaactgt
    16741 gtcagtcgct gttggctgac ctgcgatttc gggcgatcga tatcttcagt ggtaaagagg
    16801 atttgtcgtt gcagattgct taaatgcaca tcgtcgtcat ctgccagtac cagcgtcccg
    16861 acgccagcgc ccgccaggta cagcgcagca ggtgtaccca gcccgcccag accgataatc
    16921 agcacctggc tgtcgagcag tttttgctgc ccgtcaagag cgatatcgtc gagcaggatt
    16981 tggcggctat aacgcataaa atcacggtca ttcatcgcca actcctgcaa tttccagcaa
    17041 ctgtgccgtt gccaaacgcc agtctgcggc ttgagtaatg gcgctgacga cggcgatact
    17101 gccgacaccc gttgctatca ccgcaggcgc gcgtgccaga ctgacaccgc caatcgccac
    17161 ggtgggataa tccgccagtc gctcaacatg ccgtgccagc tgttccagcc cctgcggtgc
    17221 agaaggcatc tgtttggttt gcgtcgggaa cacatgtccc agcgcgatat aagaggggcg
    17281 tgctgccagc gcgacgtcga tttccatatc gtcatgtgtc gaaacgccca gccgcaggcc
    17341 tgccgcgcgg atggcattga gatcggtggc ttgcaaatct tcctgcccca aatggacgcc
    17401 atacgcctga tgcttgatcg ccagccgcca gtaatcgttg ataaacaatc gcgcgttata
    17461 gcggcggccc agcgcaattg ccgccacgac atcggcttcc acctcttcat cgcgccgatc
    17521 tttgatgcgt agctggagag tacgtacgcc tgcatccaac agacgttcga tccactgtac
    17581 gctgtccacc accgggtaca gtcctaaacg aaaaggtaca ggaggaaaat caggctgata
    17641 catcacgctt cctccttacg caggtagatt tctccgcctc tggcacggaa gttctccgac
    17701 atatccgcca ttcccatttc aatagtttgc gtggcggcgt aatcacgcac ttcctggctg
    17761 attttcatcg agcagaattt cggcccacac atggagcaaa aatgggcgac tttacctgac
    17821 tcttgcggca gggtttcatc gtgataagcg cgggcggtaa acgggtcgag ggccagatta
    17881 aactggtctt cccagcgaaa ttcgaagcgg gctttcgaca tggcgttatc gcgaatttgc
    17941 acgcccggat gccctttcgc caggtcagcg gcgtgggcgg caatcttata ggtgataagc
    18001 ccctgcttaa catcttcttt attgggcaga cccagatgct cttttggcgt tacgtaacag
    18061 agcatcgcgc agccaaacca gccaatcatc gccgcaccaa tccccgacgt gaagtggtca
    18121 tagcccggcg caatatcggt agttagcggc cccagagtgt aaaacggcgc ttcgtggcag
    18181 tgctctaact cctcggtcat attgcggcgg atcatctgca tcggcacgtg gcctgggcct
    18241 tcaatcatca cctgcacgtc atattcccag gcaattttgg tcagttcgcc cagcgtatgc
    18301 agctcggcaa actgcgcttc atcgttggcg tcctgaatag aaccggggcg cagaccgtcg
    18361 cccagcgaca gcgaaacgtc ataagcggca cagatttcac aaatttcgcg gaagtgttga
    18421 tagaggaaat tttcctgatg atgggagagg caccatttcg ccataatcga accgccgcga
    18481 gagacgatac cggtcaggcg tttcgcggtc atcggcacat agcgcagcag tacgcccgca
    18541 tggatagtga agtaatccac accttgctcg gcctgttcca gcagcgtgtc gcggaacgct
    18601 tcccaggtaa gatcttcggc gatcccgtta accttctcca gcgcctggta gatcggcact
    18661 gtaccgatcg gcaccgggct gttacgcaaa atccactcgc gggtttcgtg aatatagcga
    18721 ccggtggaga gatccatcac cgtatccgct ccccagcgcg tggaccatac cagcttttcc
    18781 acttcttctt cgatggaaga ggtgaccgcc gagttgccga tattggcgtt aacttttacc
    18841 aggaaattgc gaccaataat catcggctcc gattccggat gattaatgtt ggccgggata
    18901 atcgcacgtc cggcagcaac ttcatcacgg acaaattccg cagtgatatt ttccggcaga
    18961 cgtgcgccaa agctcattcc cggatgctgg tggcgtaaaa cttcgctacg gatgcgctcg
    19021 cggcccatat tctcgcggat ggcgatgaat tccatttccg gcgtgatgat gccctggcgg
    19081 gcgtagtgca gttgggtgac acggcgtcct gctttggcgc gttttggtgt tagtacaccg
    19141 ctaaaacgca gttcgtcgag gccatcatct gccagccgcg ctttagtgta atcggaactg
    19201 cgcacggtaa gttcttcggt atcgccgcgc gcatcgatcc acggctggcg tagttttgcc
    19261 agcccttgct gcacgttaat ggcaatctgc ggatcaccat acgggccgga ggtgtcgtag
    19321 accggaatcg cttcgttttc ttcgtactgc ggctgttctt tgctaccgcc aattagcgtc
    19381 gggctaagct ggatctcacg catcggcacg cgcacgccgg gatgtgtgcc agtgatataa
    19441 atgcgttttg agttgggaaa ggcggtgcct tccagggtgt cgataaaatg ttgggcccgg
    19501 gcgcgttgtt cgcggcgggt cagttttgtt gcagacatag ctcattccaa aaagttaagg
    19561 acgtggcttg tcagacgacg gatgaagcaa gagacgatcg ccgcaaaggc gatgcgatag
    19621 cagattaact cttgttccct tcgcaggtat tagcctgatc aggttccgcg gatcccgaat
    19681 aaacggtctc agccagttaa ggcactccga caagaaatta gcccccacaa acggggcgtt
    19741 gaatgtaaat tacgcgttaa cagcgcagaa ctcaagcagg atgtttgacg cgggcggcgt
    19801 caagcaccag cagaatcagc ttatcttcca gcacaaagcg cgcttccagc gcctcgccga
    19861 tgtcagataa aacctgttga aactcaaggt aattatcatg atcgatggcg gtttccaggc
    19921 tggaatcgta gtaatccata atctgttggg tattggcttc gagttgcggc caaatcttcg
    19981 cggcgcgcgc gagttgcccg ttgccttcca gcttatgaag aatgcgctca taaatactga
    20041 aatgtccggc agacaagtaa tcgaccaggc tctgacaaaa atcatcaagg gctttttcgt
    20101 ttagcctcat gtacgattct ttgccaggct taatgccaac cagattgtag taagccacga
    20161 gcagatgctt acgtacatgt agccagcgat caaccagttt gttacttcct ctgacgcgct
    20221 ccgtcaggtt atcgagctgg ttaagcatga ttgactccgc aagtttgtat tcaaaaactg
    20281 ctcagtgaga aatgtaaaaa ccatgttaaa catgccagtg atgcaaaggt agtgcaagag
    20341 ctatggatcg tataattgaa aaattagatc acggctggtg ggtcgtcagc catgaacaaa
    20401 aattatggtt gccgaaggga gaattgccat atggcgaagc ggcaaatttc gatcttgtgg
    20461 gtcagcgcgc actacaaatc ggcgaatggc agggggaacc tgtttggtta gtacaacagc
    20521 agcggcgtca cgatatgggg tcggtacgtc aggtcattga tctcgatgtt gggctgtttc
    20581 aactggccgg acgaggcgta caactggcgg agttttaccg atcgcataaa tactgtggtt
    20641 actgcgggca tgaaatgtat ccgagcaaaa ccgaatgggc gatgctgtgc agccattgcc
    20701 gtgagcgtta ctacccgcaa atcgccccct gcattattgt tgccatccgt cgcgatgatt
    20761 cgatcctcct cgcccagcat acccgccatc gtaacggtgt ccatacggta cttgccggat
    20821 tcgtcgaagt gggcgaaacc ctcgagcagg cggtcgcgcg ggaagtgatg gaagagagcg
    20881 gaattaaagt taaaaacttg cgttatgtga cttcccagcc gtggccgttt cctcagtctt
    20941 taatgaccgc gtttatggcg gaatatgaca gcggcgacat cgtgatcgac ccgaaagaat
    21001 tgcttgaggc gaactggtat cgctatgacg atttgccgtt actcccgccg cccggcaccg
    21061 tagcgcgccg tctgatagaa gatactgtgg cgatgtgtcg ggcagagtat gagtgatgat
    21121 acactgaccg cctgacgcac taaggaacag ccaaaatgac cgaacttaaa aacgatcgtt
    21181 atctgcgggc gctgctgcgc cagcccgttg atgtcactcc agtatggatg atgcgccagg
    21241 cgggtcgcta tctaccggaa tataaagcca cgcgcgccca ggcgggcgat tttatgtcgc
    21301 tgtgcaaaaa cgccgagctg gcgtgcgaag tgactttgca accgctgcgt cgctacccac
    21361 tggatgcggc gatcctcttt tccgatatcc tcaccgtgcc ggacgcgatg gggttagggc
    21421 tctattttga agccggagaa ggtccgcgtt ttacctcgcc agtcacctgc aaagccgacg
    21481 tcgataaact gccaattccg gacccggaag atgagctggg ttacgtgatg aacgcggtgc
    21541 gtaccattcg tcgcgaactg aaaggcgaag tgccgctgat tggtttttcc ggcagcccgt
    21601 ggacgctggc gacctacatg gtggaaggcg gcagcagcaa agcgttcacc gtgatcaaaa
    21661 aaatgatgta tgccgatccg caggcgctgc acgctctact cgataaactg gcgaaaagcg
    21721 tcactttgta tctgaatgcg cagattaaag ccggtgctca ggcagtgatg attttcgaca
    21781 cctggggcgg tgtgcttacc gggcgcgatt atcaacagtt ctcgctctat tacatgcata
    21841 aaattgttga tggtttactg cgtgaaaacg acggtcgccg cgtaccggtc acgctgttta
    21901 ccaaaggcgg cggacagtgg ctggaagcca tggcagaaac cggttgcgat gcgctgggcc
    21961 tcgactggac aacggacatc gccgatgcgc gccgccgtgt gggcaataaa gtcgcgttgc
    22021 agggtaatat ggatccgtcg atgctgtacg cgccgcctgc ccgcattgaa gaagaagtag
    22081 cgactatact tgcaggtttc ggtcacggcg aaggtcatgt ctttaacctt ggtcacggca
    22141 ttcatcagga tgtgccgcca gaacatgctg gcgtgttcgt ggaggcagtg catcgactgt
    22201 ctgaacagta tcaccgctaa ggagtgatta tggatctcgc gtcattacgc gctcaacaaa
    22261 tcgaactggc ttcttctgtg atccgcgagg atcgactcga taaagatcca ccggatctga
    22321 tcgccggagc cgatgtcggg tttgagcagg gcggagaagt gacgcgagcg gcgatggtgc
    22381 tgctgaaata tccctcgctt gagctggtcg agtataaagt tgcccgcatc gccaccacca
    22441 tgccttacat tccaggtttt ctttccttcc gcgaatatcc tgcgctgctg gcagcgtggg
    22501 agatgctgtc gcaaaagccg gatttagtgt ttgtcgatgg tcatgggatc tcgcatcctc
    22561 gccgtcttgg cgtcgccagc cattttggct tattggtgga tgtgccgacc attggcgtgg
    22621 cgaaaaaacg gctctgcggt aaattcgaac cgctctccag cgaaccgggc gcgctggccc
    22681 cactgatgga taaaggcgag cagctggcct gggtctggcg cagcaaagcg cgctgtaacc
    22741 cgttgtttat cgctaccggc catcgggtca gcgtggacag cgcgctggcg tgggtacaac
    22801 gctgcatgaa aggctatcgt ctgccggagc caacgcgctg ggcggacgcg gtggcctcgg
    22861 aacgtccggc gttcgtgcgc tatacagcaa atcagcccta attcaggtaa actgcggata
    22921 atttccgtat ttgagaactc aacatgttac aaaacccaat tcatctgcgt ctggagcgcc
    22981 tggaaagctg gcagcatgtc actttcatgg cttgcttatg cgaacgcatg taccccaatt
    23041 acgccatgtt ctgccagcaa accggttttg gtgatgggca aatttaccgt cgcattctcg
    23101 atctcatctg ggaaacgctg accgttaaag acgcaaaagt aaatttcgac agccaactgg
    23161 agaaatttga agaagcgatt ccttcagccg acgatttcga tctgtacggc gtttatccgg
    23221 caatcgatgc ctgcgtggcg ttaagtgaac tggtccattc gcgtttgagt ggtgaaacgc
    23281 tcgaacacgc ggtggaagtg agtaagacct ccatcacgac cgttgcgatg ctggaaatga
    23341 ctcaggctgg tcgcgaaatg agcgatgaag agcttaaaga aaacccagct gtagagcaag
    23401 aatgggacat tcagtgggaa atattccgac ttttagctga gtgcgaagaa cgcgatatcg
    23461 agctgataaa aggccttagg gcagacctgc gtgaggcggg tgagagcaat attggtataa
    23521 tttttcagca ataagaccag aaaacgtgat ttaacgcctg atttgtcgta cctggagtct
    23581 tccctttcgc cccccgtctg gtctacattt ggggggcgaa aaaaagtggc tatcggtgcg
    23641 tgtatgcagg agagtgctat tctggcattt ccgtcgcact cgatgcttag caagcgataa
    23701 acacattgta aggataactt atgaacaaga ctcaactgat tgatgtaatt gcagagaaag
    23761 cagaactgtc caaaacccag gctaaagctg ctctggagtc cactctggct gcaattactg
    23821 agtctctgaa agaaggcgat gctgtacaac tggttggttt cggtaccttc aaagtgaacc
    23881 accgcgctga gcgtactggc cgcaacccgc agaccggtaa agaaatcaaa attgccgcag
    23941 ctaacgtacc ggcatttgtt tctggcaagg cactgaaaga cgcagttaag taagattgcg
    24001 tggcagtgaa cagttttaac gaaggggtgg tttcacccct tttgtctttc tggcgtcgat
    24061 cattgatgct ggctggcgct ctgcttctca ctgcctgtag tcataactct tcacttcctc
    24121 cctttaccgc cagtggattt gctgaagacc agggcgcggt acgcatctgg cgaaaagaca
    24181 gcggcgataa tgtgcatctg cttgccgtgt ttagcccgtg gcgcagtggc gataccacga
    24241 cgcgagagta tcgctggcag ggcgataacc tcacgctcat caatatcaat gtttacagca
    24301 aaccgccggt gaatattcgc gcgcgttttg acgatcgcgg tgatctgagc tttatgcaac
    24361 gtgaatccga tggggaaaag cagcagcttt ctaacgacca aatcgattta taccgttatc
    24421 gtgctgatca gatccgccag attagcgatg ccttacgtca ggggagagtc gtgctgcgcc
    24481 aggggcgctg gcatgcgatg gaacagaccg tgaccacctg cgaagggcaa accattaaac
    24541 ctgatttaga ttcgcaggcg atagcgcata tcgagcgccg ccagagccgc tcttctgttg
    24601 atgtcagcgt ggcatggctg gaagcgcccg aaggttcgca attactgtta gtggcaaact
    24661 ctgatttctg tcgctggcaa cccaacgaga aaacgttctg atttaccagt ggcccatacc
    24721 catatgaccg ccaccaccgc agccgccgta gcccatgccc attccggctc cgcgcggaat
    24781 acccgcttca gccatcgcga tatctcgttt cacccgtaac tcatctaacg actgacgcaa
    24841 attctccatc tctttggcga ccgcgttaat tttgctgcta tccggtgggt tcgcggctaa
    24901 cagggcattg tattcataac gcttcgtcac cagttgctgt tgcagtgcgc tgctttgagc
    24961 gtaaaagtca ttatggattt tctgccacgc tgtctgttgt tcgctggtca aaggcgcggc
    25021 attttgctgc cacataccgt gtccgccgtg agcaaatgca gatgtcgatc ccatcgccat
    25081 tgctgaaagc gccatcatta ccagggcaat tttcgtgttc cgtttcatgg ttaatcctcc
    25141 agtggttgtc ttacttcggg tattgcatct tccgtgccaa cgatgaaacg ctgatatgac
    25201 gggtaatctg gcatgataaa cgagtaaaaa tgactcgcct gctgcgggta gcgagtcatt
    25261 tttactcatt gaaacttaag cctttgtgtt acagcgcagg gtaagcgctg ataaaagatg
    25321 gcatgatttc tgctgtcaga aagggatgag caggcaaaga agaagatgcg ttttatgcaa
    25381 cgttctaaag actccttagc taaatggtta agcgcgatcc tccccgtggt cattgttggg
    25441 ctggtgggat tgtttgcggt aactgtgatt cgtgattatg ggcgggcaag cgaggcagac
    25501 cgccaggcat tactggaaaa aggtaatgtg cttatccgcg ctctggagtc gggaagccgc
    25561 gtagggatgg ggatgcgaat gcaccatgta cagcaacagg cgcttctgga agagatggcg
    25621 ggacagccgg gagtgttgtg gttcgcagtc accgatgcgc agggcatcat tattcttcat
    25681 agcgaccccg ataaggtcgg gcgtgcgctc tattcgccgg atgaaatgca gaaattaaag
    25741 ccagaggaaa actcccgctg gcggctgctt gggaaaacgg aaactacgcc tgcacttgag
    25801 gtctatcgtt tgttccagcc aatgtcagcg ccctggcggc atggaatgca caatatgccg
    25861 cgctgtaacg gcaaagctgt gccacaagta gatgcacaac aggctatttt tatcgccgtt
    25921 gatgccagtg atctggttgc aacccagagt ggggaaaagc gcaataccct gattatcctc
    25981 ttcgccctgg cgacggtctt gctggcaagc gtattgtcat tcttctggta tcgccgctat
    26041 ctgcgctcgc gccagcttct acaagatgaa atgaagcgca aagagaagct ggtggcgctg
    26101 gggcatcttg cggcaggcgt tgcccacgaa atccgtaacc cactttcctc gattaaagga
    26161 ctggcgaaat actttgccga gcgcgcgcct gcagggggag aagcgcatca actggcgcag
    26221 gtgatggcga aagaggccga ccgtttaaac cgcgtggtaa gcgagttgct ggaactggtt
    26281 aagccaacgc atctggcttt gcaggcggtg gatctcaaca cgctgattaa ccactcatta
    26341 cagctggtaa gtcaggatgc aaacagccgg gagatccagt tacgctttac cgccaacgac
    26401 acattaccgg aaattcaggc cgacccggac aggctgactc aggtcctgtt gaatctctat
    26461 ctcaatgcta ttcaggcgat tggtcagcat ggcgtgatta gcgtgacggc cagcgaaagc
    26521 ggcgcgggcg tgaaaatcag cgttaccgac agcggtaagg gaattgcggc agatcagctt
    26581 gatgccatct tcactccgta cttcaccact aaagccgaag gcaccggatt ggggctggcg
    26641 gtcgtgcata atattgttga acaacacggt ggtacaattc aggtcgcaag ccaggaggga
    26701 aaaggctcaa cgttcaccct ctggcttccg gtcaatatta cgcgtaagga cccacaagga
    26761 tgacgcacga taatatcgat attctggtgg tggatgatga cattagccac tgcactattt
    26821 tgcaggcttt actgcgcggc tggggctata acgtcgcgct ggcgaacagc gggcgacagg
    26881 cgttggagca ggtgcgggaa caggtttttg atcttgtgct ttgcgatgtg cgaatggcgg
    26941 agatggacgg catcgccacg ctgaaagaga tcaaagcgtt aaacccggca attccggtgc
    27001 tgattatgac tgcgtactcc agcgtcgaga cggcggtaga ggcactgaaa actggggcgc
    27061 tggattatct catcaagccg ctggatttcg ataacctaca ggcgacgctg gaaaaagcgc
    27121 tcgcgcatac gcacagtatt gatgctgaaa cacctgcggt gactgccagc cagttcggta
    27181 tggtcggtaa aagcccggcg atgcaacacc tgctcagtga aatcgccctc gtcgcgccat
    27241 cggaagccac ggtactgatc cacggcgatt ccggcaccgg taaagagctg gtcgccaggg
    27301 cgattcacgc cagtagcgca cgtagcgaaa aaccgctggt aacgctcaac tgtgcggcac
    27361 tcaacgaatc cttgctggaa tctgaattgt tcggtcacga aaaaggggcg tttactggag
    27421 ccgataaacg ccgggaaggg cgctttgttg aggcggacgg cggcacgctg tttctcgatg
    27481 aaattggcga tatctcgccg atgatgcagg tgcgtctgct gcgtgcgatt caggagcgcg
    27541 aagttcagcg tgtcggtagc aaccagatta tctcggttga tgtccggctg attgcggcga
    27601 cccatcgcga tcttgccgca gaggtgaatg ccgggcgttt tcgccaggat ctctactatc
    27661 gcctgaatgt ggtggcgatt gaagtaccat cgctgcggca acggcgggaa gatatccctc
    27721 tgctggctgg ccattttctg cagcgctttg ccgagcgtaa tcgcaaggcg gtaaaaggtt
    27781 ttacgcccca ggcgatggat ctgttgattc attacgactg gccgggaaat attcgtgagc
    27841 tggaaaacgc ggtggaacgg gcagtggtgc tgctgaccgg ggaatatatt tccgaacgcg
    27901 agctgccgct ggcgattgcc agtacgccga tcccgctggg acaaagtcag gatattcagc
    27961 cgttggtgga agtggaaaaa gaggtgattc tggcggcgct ggagaaaacg ggcggcaaca
    28021 aaaccgaagc cgcccgtcag ttagggatca cgcgcaaaac gctattggca aaactgtcgc
    28081 gttagttctg ctcgcgttcg atagcgcgcc agccgatatc tttccggcag aagcagtcgt
    28141 cccagtggat atcggtcatt aaggcatagg cgcgtttctg cgcttctgcc acggtatgac
    28201 ccagcgcggt gacgcacagt acgcgcccgc cgttggtcac tacctgctcg tcatccgcca
    28261 gttttgtgcc cgcgtggaac actttgccgc ctgccacttc ttccagcggc aggccgtgga
    28321 tcacgtcacc ggtgcggtaa tcacccggat atccacccgc agccatcacc acgccgagag
    28381 aagcgcgttc atcccactcg gacgttttct cgtccagttt gctttcacag gccgccaggc
    28441 agagctcaac cagatcggac ttcatgcgca gcataatcgg ctgggtttcc ggatcgccaa
    28501 agcggcagtt aaattcaata accttcggat tgccctgttt gtcgatcatc aggcccgcgt
    28561 agagaaaacc ggtgtaggtg ttgccttccg ccgccatgcc tttcacggtt ggccagataa
    28621 tacgttccat ggtgcgctga tgaacgtcat cggttactac cggcgcgggg gagtaagcgc
    28681 ccatcccgcc ggtgtttggt ccggtatctt tatcgcctac gcgtttgtga tcctggctgg
    28741 tagccatcgg cagcacatgc tcgccgtcca ccatcacgat aaagctcgct tcttcgccat
    28801 cgaggaactc ttcgataacg atgcgatgac ccgcgtcgcc aaaagcgttg cccgccagca
    28861 tatcgtgaac agccgcttcc gcttcttcca gcgtcatcgc cacgataacg cctttcccgg
    28921 cagccagacc gtccgcttta atgacgattg gcgcgccttt ctcacgcaga tacgccagcg
    28981 caggttctac ctcggtgaag ttctggtatt ccgccgtagg gatcttatgg cgggccagga
    29041 aatctttggt aaacgctttt gagccttcca gttgggccgc acctgcggtt gggccgaaga
    29101 ttttcagccc ggcggcgcgg aaggtatcga ccacgccttt caccagcggc gcttccgggc
    29161 cgacgatggt cagatcaatc ttttcgtttt gtgcgaaatc caacagcgcc gggatatcgg
    29221 tcacgccaat agcaacgttt tgcagcgcgg gttccagtgc agtgcctgca ttacccggag
    29281 caacaaaaac agtctcaacc agcggcgact gggccgcttt ccaggccagc gcgtgctcgc
    29341 gcccgccgtt accaatcact aatactttca tctattgctc cattaatggc ggaagtggcg
    29401 catgtcggtg aagagcatcg caataccgtg ctcgtcggcg gcggcaatca cttcgtcatc
    29461 acggatagaa ccgccaggct ggattacgca ggtcacgccc gcagcggcgg cggcatcaat
    29521 accgtcgcgg aacgggaaga acgcgtcaga agccatcgag gaacctttca cttccaggcc
    29581 ttcatcggcc gctttaatac cggcgatttt tgcggagtac acgcggctca tctggcccgc
    29641 gccaatgccg atagtcatat tgtttttggc atagacgata gcgttggatt tcacaaactt
    29701 cgccaccttc cagcagaaca gcgcatcacg cagttcctgt tcgctcggct gacgtttggt
    29761 caccacgcgc agttcttccg caccgaccat ccccaggtca cgatcctgaa ccagcagacc
    29821 gccgttcacg cgtttgaaat cgaggcccgg aacacgctcg ccccactgac cgcaggtcag
    29881 aacgcgtacg ttctgtttgg cggcggtgat tttcagggct tcttcgctgg cggacggcgc
    29941 aataatcact tcgacaaact gacgagaaat gatggcctgt gcggtttccg catccagctc
    30001 gcggttaaag gcaatgatgc cgccgaatgc ggaggttggg tcggttttgt acgcgcgatc
    30061 gtaagcatca agaatggaat tgccgatagc cacgccgcaa gggttggcgt gcttcacaat
    30121 cacacatgcc ggctcggcga actctttcac gcactccagc gccgcatcgg tatcggcgat
    30181 gttgttataa gagagggctt taccctgaac ctgggttgcg gtagcaacgg aggcttcttt
    30241 cacattctct tctatataga aggcagcctg ctggtggctg ttctcgccgt aacgcatatc
    30301 cagcttctta atgaagttca ggttcagcgt gcgtgggaag cgaccggcgg cttctttgct
    30361 ttcaccgtgg taagccggaa ccatgctgcc gaagtagttg gcaatcatgc tgtcgtaggc
    30421 ggcagtgtgt tcgaaggctt tgatggcgag gtcgaaacgg gttgcaagcg tcagcgatcc
    30481 ttcgttgtca tccatctctt taataatggc gtcatagtcg ctgctcttca ccacgattgc
    30541 gacatcttta tggttcttgg cggcggagcg caccatcgtt gggccgccga tatcgatgtt
    30601 ctcaaccgca tcttccagcg agcaaccttc acgggccacg gtctgggcga acggatacag
    30661 gttaacaacc accatatcga taggctggat ctgatgttct tccataatgg catcgtcctg
    30721 gccgcgacgg cccagaatgc caccatgtac tttcggatgc agggtcttca cgcgtccatc
    30781 catcatctcc gggaaaccgg tgtaatcgga aacttcggtt accggcagac ctttttctgc
    30841 taacagacgg gcagtgcccc ctgtagacag cagctccaca ccgcgtgcgg aaagtgcctg
    30901 ggcgaattcg acgataccgg ctttgtcaga aacactgagc agagcgcggc ggactggacg
    30961 acgttgttgc atggtaaatc ccctggattt gactattaca gagagcgtta gctgaatttt
    31021 tcgcgaaaaa ctcagctaac gcccctaacg gggcatcctt atttttcgcc cgcattgtaa
    31081 cgaaaacgtt tgcgcaacgc tcgcgaattt ttctctttca atggtgatca caattttgac
    31141 tgtggttacc gtgggcaaaa tacagaaatt acattgatga ttgtggataa ctctgtgcgt
    31201 aaaaaggtat aaagcgggct tttgctgggg aatgcagcag tcagtcattt ttctgcaatt
    31261 tttctattgc ggcctgcgga gaactcccta taatgcgcct ccatcgacac ggcggatgtg
    31321 aatcacttca cacaaacagc cggttcggtt gaagagaaaa atcctgaaat tcagggttga
    31381 ctctgaaaga ggaaagcgta atatacgcca cctcgcgaca gtgcgctaaa gcgcgtcgca
    31441 actgctcttt aacaatttat cagacaatct gtgtgggcac tcgaagatac ggattcttaa
    31501 cgtcgcaaga cgaaaaatga ataccaagtc tcaagagtga acacgtaatt cattacgaag
    31561 tttaattctt tgagcatcaa acttttaaat tgaagagttt gatcatggct cagattgaac
    31621 gctggcggca ggcctaacac atgcaagtcg aacggtaaca ggaagaag
//
LOCUS       DAPHKZ010000045        31580 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.045, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000045 DAPHKZ010000000
VERSION     DAPHKZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31580
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.045"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..528)
                     /gene="fliZ"
                     /locus_tag="RH288_002185"
     CDS             complement(<1..528)
                     /gene="fliZ"
                     /locus_tag="RH288_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HDV4031233.1"
                     /translation="MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIV
                     NKIEISRLDTLLDENGWQVEQQSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEM
                     SPGTVREYVVRLRRLGNHLHEQNISLEQLQDGFLDEILAPWLPTTSTNNYRIALRKYQ
                     HYQRQTCTGLVQKSSS"
     gene            complement(574..1293)
                     /gene="fliA"
                     /locus_tag="RH288_002186"
     CDS             complement(574..1293)
                     /gene="fliA"
                     /locus_tag="RH288_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HDV4031234.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVERYDALQGTTFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TDDHQRENPLQQLLDSNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            complement(1613..3325)
                     /locus_tag="RH288_002187"
     CDS             complement(1613..3325)
                     /locus_tag="RH288_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin FliC"
                     /protein_id="HDV4031235.1"
                     /translation="MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDD
                     AAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQATTG
                     TNSDSDLDSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKDGSMKIQVGANDGETITIDL
                     KKIDSSTLKLTSFNVNGKGAVDNAKATEADLTAAGFSQSAVVSGNSTWTKSTVTTFNA
                     ATATDVLASVSGGSTISGYAGTNNGLGVAASTAYTYNATSKSYSFDATALTNGDGTAG
                     STKVADVLKAYAANGDNTAQISIGGSAQEVKIASDGTLTDTNGDALYIGADGNLTKNQ
                     AGGPAAATLDGIFNGANGHDAVDAKITFGSGMTVDFTQVSNNVDIKGATVSAEDMNTA
                     LTGQAYTVANGAQSYDVAADGAVTATTGGATVNIGAEGELTTAANKTVTETYHEFANG
                     NILDDDGAALYKAADGSLTTEATGKSEATTDPLKALDDAIASVDKFRSSLGAVQNRLD
                     SAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLS
                     LLQG"
     gene            3591..4997
                     /gene="fliD"
                     /locus_tag="RH288_002188"
     CDS             3591..4997
                     /gene="fliD"
                     /locus_tag="RH288_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDV4031236.1"
                     /translation="MASISSLGVGSGLDLSSILDSLTAAQKATLTPISNQQSSFTAKL
                     SAYGTLKSALTTFQTANTALSKADLFSATSTTSSTTAFSATTAGNAIAGKYTISVTHL
                     AQAQTLTTRTTRDDTKTAIATSDSKLTIQQGGDKDPITIDISAANSSLSGIRDAINNA
                     KAGVSASIINVGNGEYRLSVTSNDTGLDNAMTLSVSGDDALQSFMGYDASASSNGMEV
                     SVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQTAIK
                     DWVNAYNSLIDTFSSLTKYTAVDAGADSQSSSNGALLGDSTLRTIQTQLKSMLSNTVS
                     SSSYKTLAQIGITTDPSDGKLELDADKLTAALKKDASGVGALIVGDGKKTGITTTIGS
                     NLTSWLSTTGIIKAATDGVSKTLNKLTKDYNAASDRIDAQVARYKEQFTQLDVLMTSL
                     NSTSSYLTQQFENNSNSK"
     gene            5022..5432
                     /gene="fliS"
                     /locus_tag="RH288_002189"
     CDS             5022..5432
                     /gene="fliS"
                     /locus_tag="RH288_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDV4031237.1"
                     /translation="MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARL
                     FMQDNNQQGKGVSLSKAINIIENGLRVSLDEDSKDELTQNLIALYSYMVRRLLQANLR
                     NDVSAVEEVEALMRNIADAWKESLLSPSLIQDPV"
     gene            5432..5797
                     /gene="fliT"
                     /locus_tag="RH288_002190"
     CDS             5432..5797
                     /gene="fliT"
                     /locus_tag="RH288_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HDV4031238.1"
                     /translation="MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAV
                     QEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSV
                     LSAYGDQGGFVLAPQDNFS"
     gene            5875..7362
                     /gene="amyA"
                     /locus_tag="RH288_002191"
     CDS             5875..7362
                     /gene="amyA"
                     /locus_tag="RH288_002191"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HDV4031239.1"
                     /translation="MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPA
                     YKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAAIDALKRNDIAVLLDVV
                     VNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCF
                     SGIDHIENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTQCDGFRLDAVKHIPAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQT
                     YIDQVEGKTMLFDAPLQMKFHEASRMGRDYDMTQIFTGTLVEADPFHAVTLVANHDTQ
                     PLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGQTYPIDMPII
                     EQLDELILARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTINLG
                     ENYGNKTWRDFLGNRQESVVTDENGEATFFCNGGSVSVWVIEEVI"
     gene            complement(7396..7809)
                     /locus_tag="RH288_002192"
     CDS             complement(7396..7809)
                     /locus_tag="RH288_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310694.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV4031240.1"
                     /translation="MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLAGYWQTKGPQ
                     RALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKLTLMSDDLTNVTVKRELYEVERD
                     GNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP"
     gene            7996..9201
                     /gene="yedE"
                     /locus_tag="RH288_002193"
     CDS             7996..9201
                     /gene="yedE"
                     /locus_tag="RH288_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HDV4031241.1"
                     /translation="MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYV
                     QLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFTALMLIIGWEKRFFRRA
                     APQTAKEIA"
     gene            9198..9431
                     /gene="yedF"
                     /locus_tag="RH288_002194"
     CDS             9198..9431
                     /gene="yedF"
                     /locus_tag="RH288_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDV4031242.1"
                     /translation="MKNIIPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            9540..10208
                     /locus_tag="RH288_002195"
     CDS             9540..10208
                     /locus_tag="RH288_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HDV4031243.1"
                     /translation="MCGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKV
                     LLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSRMFKPLWQHGRAICFADG
                     WFEWKKEGDKKQPYFIYRADGQPVFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIH
                     DRRPLVLSPEAAREWMRQEIGGKEASEIATNGCVPANQFTWHPVSRAVGNVKNQGAEL
                     IQPV"
     gene            complement(10601..10915)
                     /gene="fliE"
                     /locus_tag="RH288_002196"
     CDS             complement(10601..10915)
                     /gene="fliE"
                     /locus_tag="RH288_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDV4031244.1"
                     /translation="MSAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDR
                     ISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            11130..12788
                     /gene="fliF"
                     /locus_tag="RH288_002197"
     CDS             11130..12788
                     /gene="fliF"
                     /locus_tag="RH288_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDV4031245.1"
                     /translation="MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAK
                     APDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGL
                     PKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPS
                     LFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLT
                     QFNTSGRDLNDAQLKYASDVEGRIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTE
                     EQYRPNGDESHAALRSRQLNESEQSGSGYPGGVPGALSNQPAPANNAPISTPPANQNN
                     RQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGK
                     PLPLSNEQMKQIEDLTREAMGFSEKRGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQ
                     LLAAGRWLLVLLVAWLLWRKAVRPQLTRRAEAMKAVQQQAQAREEVEDAVEVRLSKDE
                     QLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE"
     gene            12781..13776
                     /gene="fliG"
                     /locus_tag="RH288_002198"
     CDS             12781..13776
                     /gene="fliG"
                     /locus_tag="RH288_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDV4031246.1"
                     /translation="MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANV
                     TQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRD
                     TASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            13769..14455
                     /gene="fliH"
                     /locus_tag="RH288_002199"
     CDS             13769..14455
                     /gene="fliH"
                     /locus_tag="RH288_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDV4031247.1"
                     /translation="MSDNLPWKTWTPDDLAPPQAEFVPMVEPEETIIEEAEPSLEQQL
                     AQLQMQAHEQGYQAGIAEGRQQGHEQGYQEGLARGLEQGLAEAKSQQAPIHARMQQLV
                     SEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGK
                     PQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQE
                     LCRLAAPGVV"
     gene            14455..15828
                     /gene="fliI"
                     /locus_tag="RH288_002200"
     CDS             14455..15828
                     /gene="fliI"
                     /locus_tag="RH288_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellum-specific ATP synthase FliI"
                     /protein_id="HDV4031248.1"
                     /translation="MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAE
                     GLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLD
                     TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFK
                     QLLSSFQRNRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLE
                     RIFPTVS"
     gene            15847..16290
                     /gene="fliJ"
                     /locus_tag="RH288_002201"
     CDS             15847..16290
                     /gene="fliJ"
                     /locus_tag="RH288_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FliJ"
                     /protein_id="HDV4031249.1"
                     /translation="MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWR
                     EKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE"
     gene            16287..17414
                     /gene="fliK"
                     /locus_tag="RH288_002202"
     CDS             16287..17414
                     /gene="fliK"
                     /locus_tag="RH288_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook length control protein FliK"
                     /protein_id="HDV4031250.1"
                     /translation="MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTD
                     KAAPQLLVATDKPTTKGEPLVSEILADAQQADLLIPVDETPPVINDEQSTSTPLTTAQ
                     TMTLAAVAGNNTAKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDVPSTVLPAEKP
                     TLFTKLTSAQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPH
                     QTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLK
                     VDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ
                     QQQSQRTVNHEPLAGEDDDTLPVPVSLQGRVTGNSGVDIFA"
     gene            17519..17983
                     /gene="fliL"
                     /locus_tag="RH288_002203"
     CDS             17519..17983
                     /gene="fliL"
                     /locus_tag="RH288_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HDV4031251.1"
                     /translation="MTDYAISKKSKRSLWIPILVFITLAACASAGYSYWHSHQVAADD
                     KAQQRVVPSPVFYALDTFTVNLGDADRVLYIGITLRLKDEATRSRLSEYLPEVRSRLL
                     LLFSRQDAAVLATEEGKKNLIAEIKTTLSTPLVAGQPKQDVTDVLYTAFILR"
     gene            17988..18992
                     /gene="fliM"
                     /locus_tag="RH288_002204"
     CDS             17988..18992
                     /gene="fliM"
                     /locus_tag="RH288_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HDV4031252.1"
                     /translation="MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQR
                     RVVRERLQALEIINERFARHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRNEDQNWRDNLVRQVQHSQLELVANFADISLRLSQIL
                     KLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTLNGQYALRIEHLINPILNSLNEEQPK
                     "
     gene            18989..19402
                     /gene="fliN"
                     /locus_tag="RH288_002205"
     CDS             18989..19402
                     /gene="fliN"
                     /locus_tag="RH288_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HDV4031253.1"
                     /translation="MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAADAVFQQFGG
                     GDVSGTLQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR"
     gene            19405..19770
                     /gene="fliO"
                     /locus_tag="RH288_002206"
     CDS             19405..19770
                     /gene="fliO"
                     /locus_tag="RH288_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliO"
                     /protein_id="HDV4031254.1"
                     /translation="MNNHATVQSSTPVSAAPLLQVSGALIAIIALILAAAWLVKRLGF
                     APKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEI
                     PQTDFQSVMKNLLKRSGRS"
     gene            19770..20507
                     /gene="fliP"
                     /locus_tag="RH288_002207"
     CDS             19770..20507
                     /gene="fliP"
                     /locus_tag="RH288_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310714.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDV4031255.1"
                     /translation="MRRLLSVAPVLLWLVTPLAFAQLPGITSQPLPGGGQSWSLPVQT
                     LVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            20517..20786
                     /gene="fliQ"
                     /locus_tag="RH288_002208"
     CDS             20517..20786
                     /gene="fliQ"
                     /locus_tag="RH288_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDV4031256.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQI
                     NEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG"
     gene            20795..21580
                     /gene="fliR"
                     /locus_tag="RH288_002209"
     CDS             20795..21580
                     /gene="fliR"
                     /locus_tag="RH288_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliR"
                     /protein_id="HDV4031257.1"
                     /translation="MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKL
                     GLAMMITFAIAPSLPANDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEII
                     GLQMGLSFATFVDPASHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG
                     GEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGISLMAALMPLIAPFCEHLFSEMFNLLADIISELPLI"
     gene            21870..22493
                     /gene="rcsA"
                     /locus_tag="RH288_002210"
     CDS             21870..22493
                     /gene="rcsA"
                     /locus_tag="RH288_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HDV4031258.1"
                     /translation="MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACD
                     SQRPSVVFINEDCFIHDASNSQRIKHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLL
                     ISSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
                     QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR"
     gene            complement(22537..22725)
                     /gene="dsrB"
                     /locus_tag="RH288_002211"
     CDS             complement(22537..22725)
                     /gene="dsrB"
                     /locus_tag="RH288_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HDV4031259.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNEAGHQDGIFVEKAE"
     gene            22888..23115
                     /gene="yodD"
                     /locus_tag="RH288_002212"
     CDS             22888..23115
                     /gene="yodD"
                     /locus_tag="RH288_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid resistance protein YodD"
                     /protein_id="HDV4031260.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHV
                     SVDGREYHTWRELADAFELDIHDFSVSEVNR"
     gene            23413..24228
                     /locus_tag="RH288_002213"
     CDS             23413..24228
                     /locus_tag="RH288_002213"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HDV4031261.1"
                     /translation="MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLREANVPVI
                     LCSSKTSAEMLYLQKTLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEISQ
                     VLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQ
                     FTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGKRPTTLGLGDGPND
                     APLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWGEGLDHFFSAR"
     gene            complement(24225..25919)
                     /gene="yedQ"
                     /locus_tag="RH288_002214"
     CDS             complement(24225..25919)
                     /gene="yedQ"
                     /locus_tag="RH288_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
                     /protein_id="HDV4031262.1"
                     /translation="MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWRE
                     VVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAV
                     TEFEQHRDEHAWQIELNRRRTLSVNGVSDALVSEGNLLSRENESLDNEITAALEVGYL
                     LRLAHNTSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRH
                     RAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLRNAIDKNLD
                     GEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDSRYVSWERL
                     DHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQS
                     SLQWQAWHDTLTRLYNRGALFEKARPLAKLYQTHQHPFSVIQVDLDHFKAINDRFGHQ
                     AGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGASLTEAAEVAERIRLKLNEKE
                     MLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVCASDNA"
     gene            complement(26157..26339)
                     /locus_tag="RH288_002215"
     CDS             complement(26157..26339)
                     /locus_tag="RH288_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2158 domain-containing protein"
                     /protein_id="HDV4031263.1"
                     /translation="MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFH
                     ETELVPGEGSRPAEEV"
     gene            complement(26418..27335)
                     /locus_tag="RH288_002216"
     CDS             complement(26418..27335)
                     /locus_tag="RH288_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HDV4031264.1"
                     /translation="MLLAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLN
                     AQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIISAFIPWAITPLLMIGGAFLCF
                     EGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVA
                     ITLGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALG
                     KGLLIIAPWLMKALSIVGTLAMFLVGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPT
                     VLNLILGFIIGGIVVLGVKAVAKIRGQAH"
     gene            27508..28428
                     /gene="yedA"
                     /locus_tag="RH288_002217"
     CDS             27508..28428
                     /gene="yedA"
                     /locus_tag="RH288_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HDV4031265.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LAAGILLMAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
                     SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVI
                     VFAVVLVTLGKYLFPANPVVAPVIQDASSE"
     gene            complement(28417..28887)
                     /gene="vsr"
                     /locus_tag="RH288_002218"
     CDS             complement(28417..28887)
                     /gene="vsr"
                     /locus_tag="RH288_002218"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VSPR family DNA mismatch endonuclease"
                     /protein_id="HDV4031266.1"
                     /translation="MADVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDA
                     SLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKIGKNVERDRRDIS
                     RLQELGWRVLIVWECALRGREKLTDEALSERLEEWICGEGASAQIDTQGIHLLA"
     gene            complement(28868..30286)
                     /gene="dcm"
                     /locus_tag="RH288_002219"
     CDS             complement(28868..30286)
                     /gene="dcm"
                     /locus_tag="RH288_002219"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-cytosine methyltransferase"
                     /protein_id="HDV4031267.1"
                     /translation="MQENISVTDSYSTGNAAQAMLEKLLQIYDVKTLVAQLNGVGENH
                     WSAAILKRALANDSAWHRLSEKEFAHLQTLLPKPPAHHPHYAFRFIDLFAGIGGIRRG
                     FESIGGQCVFTSEWNKHAVRTYKANHYCDPATHHFYEDIRDITLSHKEGVSDEAAAEH
                     IRKHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDARRP
                     AMFVLENVKNLKSHDQGKTFRIIMQTLDELGYDVADAEDNGPDDPKIIDGKHFLPQHR
                     ERIVLVGFRRDLNLKADFTLRDISECFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYR
                     YAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMATGEKDFDDP
                     LNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLL
                     EPKIKQAVALRQQEAQHGRRSR"
     gene            complement(30353..31048)
                     /locus_tag="RH288_002220"
     CDS             complement(30353..31048)
                     /locus_tag="RH288_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDV4031268.1"
                     /translation="MDLQHWQAQFENWLKNHHQHQDAAHDVCHFRRVWATAQKLAADD
                     DVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFEQFPAEKIEAVCH
                     AIAAHSFSAQIAPLTTEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDGEDPFAQ
                     HRPLDDKRYALDHFQTKLLKLPQTMQTARGKQLAQHNAHFLVEFMAKLSAELAGENEG
                     VDHKVIDAFSPAG"
     gene            complement(31088..31453)
                     /locus_tag="RH288_002221"
     CDS             complement(31088..31453)
                     /locus_tag="RH288_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDV4031269.1"
                     /translation="MEKCDFYHIIVLSLNFPGYLKMEYGSTKMEERLSRSPGGKLALW
                     AFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGAL
                     LGSIAWYTRPRPARSRRYE"
BASE COUNT         7637 a         8258 c         8128 g         7557 t
ORIGIN      
        1 gctggaggat ttctgcacaa gtccggtaca ggtttggcgc tgatagtgtt gatacttccg
       61 taacgcgatg cggtaattgt tggtgctggt ggtgggcagc cacggggcga ggatttcatc
      121 aaggaaaccg tcctgcagct gttcgaggga aatattttgc tcgtgtagat gattccccaa
      181 acggcgcaaa cgaacgacat attcacgcac cgtacctggg ctcatttcag tttgctcaaa
      241 aagaaattgc ttaaagccga taatatcgaa aaaatcactc tgcgttttgc agtgtaaatc
      301 accgcaaaat cggcacaatg ccgcccatga ttgttgttcc acttgccagc cattttcatc
      361 aagcagcgtg tccaggcggg aaatctcgat tttattcact attttgccgt cgcgaactaa
      421 ggtaatgcga tcgagtaatt tacggcaatg cgcacaatgg gtctggctgt gtttaaagtc
      481 tttaagatag cggcttaatg gccgtctttt caggtgctgc accatcatta agaactcctg
      541 gtagtcaaag ttaaagtgcg gcatttactg acgttataac ttacccagtt tagtgcgtaa
      601 ccgtttaatg gcctggctgt gtaactgact gacccgcgat tccccgacct ccagcaccgc
      661 gccaatctct ttgagattca gctcttcctg gtaatagagg gttaatacca gtttttcgcg
      721 ctccggcagc gtttcgatag cttccatcac ccgctggcgc agattactgt ccagcagttg
      781 ttgtagcggg ttttctcgct gatgatcatc agtaaccagt tcgatgctat cgccgtgctc
      841 ttcgcgccac tcatcgtagg agaagagctg gctgttattg gtgtcgagca acatttggcg
      901 ataatcggca atatcgatcc ctaaacgttc cgctacctca gtttccgtgg cgttgcggcc
      961 aagttcctgc tccagttgcc ctattgcctg tgccacttca cgcgcgttgc gtcgcacgct
     1021 gcgcggcacc cagtcacggc tgcgaagttc atccagcata gcgccacgga tacgctgcac
     1081 tgcgtaagtt gtaaatgtcg ttccttgtag ggcgtcatag cgttcgacgg cattaagtaa
     1141 cccaatgccg cccgcctgta gcagatcgtc aagttccacg ctcgcgggca gtcgaacctg
     1201 caggcgcaat gcttcgtgac gcaccagcgg gacataacgc tgccacagcg agtgtttatc
     1261 cattacacct tcagcggtat agagtgaatt cacgataaac agccctgcgt tatatgagtt
     1321 atcggcatga ttatccgttt ctgcagggtt tttaatcgga cgattagtgg gtgaaatgag
     1381 gggttatttg ggggttaccg gtaaattgcg aacagaaaaa accccgccgg tggcggggga
     1441 gcacgttgct gacaaattgc gcttcatgtt gccggatgtg gcgtaaacgc cttatccggc
     1501 ctacaaaaat gtgcaaattc aataaattgc agttcacctt gtaggcctga taagcacagc
     1561 gcaccaggca atttggcgtt gccgtcagtc tcagttaatc aggttacgac gattaaccct
     1621 gcagcagaga cagaacctgc tgcggtacct ggttagcttt tgccagcacg gagttaccgg
     1681 cctgctggat gatctgcgct ttcgacatgt tggacacttc ggtcgcatag tcggcgtcct
     1741 gaatacggga ctgcgcttcg gacaggttgg tagtggtgtt gttcaggttg gtgactgcgg
     1801 aatccagacg gttctgcacg gcacccaggg aagaacggaa tttgtctacg gatgcgatag
     1861 catcgtccag cgctttcagc ggatccgtgg tcgcttcaga tttacctgta gcttcagtgg
     1921 tcagagagcc gtcagccgct ttatacagag ccgcgccgtc atcatccaga atattgccgt
     1981 tagcaaattc gtgataagtt tctgtgacag tcttgttggc cgcagtcgtc agttcaccct
     2041 cagcaccaat atttacggtc gctccacctg tagtagcagt tactgcacca tcagcggcaa
     2101 cgtcataaga ctgtgcgccg ttagctacgg tataagcctg accggttaac gcagtgttca
     2161 tatcttcggc ggataccgtc gcgcccttaa tatccacatt gttgctaacc tgggtgaagt
     2221 caacggtcat gccgctgccg aaggtaatct tcgcatcaac tgcatcatga ccattcgcac
     2281 cgttgaaaat accgtccaac gttgccgcgg ctgggccgcc ggcctggttt ttcgtcaggt
     2341 taccgtcagc accaatgtat aaagcatcgc cattagtatc cgtcagggta ccatcgctgg
     2401 caattttaac ttcctgagcg ctaccaccga tggagatctg agccgtgtta tcgccgtttg
     2461 ctgcataggc tttcagaaca tcagcaactt tagttgagcc cgcagtacca tcaccattag
     2521 taagtgcggt tgcgtcaaat gaataagact tgctggttgc gttgtaggta tatgcagtag
     2581 aagccgctac gcctaaccca ttgtttgtgc cagcataacc gctaatagtg ctgccgccac
     2641 taacgctagc cagcacatcg gtagctgttg ctgcattaaa ggtagtaaca gtagatttag
     2701 tccaggtgct attgccactg acaactgcac tttgggagaa gcccgcagcg gtcagatctg
     2761 cttcagtggc ttttgcatta tcaacagcgc ctttaccgtt gacgttgaag ctggtcagct
     2821 tcagtgtaga agagtcgatt tttttcaggt caatcgtgat ggtttcacca tcatttgcgc
     2881 ccacctgaat tttcattgaa ccgtctttgg acaacacatt cacgccattg aactgggtct
     2941 gaccagatac gcggtcaatt tcatcaagac gagatttgat ttcgtcctgg atggagtcca
     3001 ggtcagaatc ggagttagta ccggtagtgg cctgaaccgt cagttcacgg atacgctgta
     3061 agttgttgtt gatttcggac agcgcgcctt cggtggtctg cgcaacggaa ataccgtcgt
     3121 tggcgttacg tgcagcctga gtcaggcctt taatgttaga agtaaaacgg ttagcaatcg
     3181 cctgacccgc ggcgtcatcc ttcgcgctgt taatacgcaa gccagaagac agacgctcga
     3241 tagaactcga cagcgcagac tggttcttgt tgatattatt ttgagtgatc agcgagaggc
     3301 tgttggtatt aatgacttgt gccatgattc gttatcctat attgcaagtc gttgattacg
     3361 tattgggttt ccacccgtcg gctcaatcgc cgtcaaccct gttatcgtct gtcgtaaaac
     3421 aacctttaga atttttttca caaacagcca ttttttgtta gtcgccgaaa tactcttttc
     3481 tctgcccctt attcccgcta ttaaaaaaaa caattaaacg taaactttgc gcaattcagg
     3541 ccgataaccc cggtattcgt tttacgtgtc gaaagataaa aggaaatcgc atggcaagta
     3601 tttcatcgct gggagtcggg tcaggcctgg atttaagttc aatccttgat agcctcaccg
     3661 ccgcgcaaaa agcgacgcta acccctattt caaatcagca atcgtcgttt accgctaaac
     3721 ttagcgccta cggtacgctg aaaagcgcgt tgacgacttt ccagaccgcc aatactgcat
     3781 tgtctaaagc cgatcttttt tccgccacca gcactaccag cagcaccacc gcgttcagtg
     3841 ccaccaccgc gggtaacgcc atcgccggga aatacaccat cagcgtcacc catctggcgc
     3901 aggcgcaaac cctgaccacg cgcaccacca gagatgatac gaaaacggcg atcgccacca
     3961 gcgacagtaa actcaccatt caacaaggcg gcgacaaaga tccgattacc attgatatca
     4021 gcgcggctaa ctcgtcgtta agcgggatcc gtgatgccat caacaacgca aaagcgggcg
     4081 taagtgcgag catcattaac gtgggtaacg gtgaatatcg tctgtcagtc acatcaaatg
     4141 acaccggcct tgacaatgcg atgacactct cggtcagcgg tgatgatgcg ctacaaagtt
     4201 ttatgggcta tgacgccagt gccagcagca acggcatgga agtctcggtc gccgcccaga
     4261 atgcgcagct gacggtcaac aacgtcgcca ttgagaacag cagcaacacc atcagcgacg
     4321 cgctggaaaa catcaccctg aacctgaacg atgtcaccac gggcaaccag acgctgacca
     4381 tcactcagga cacctccaaa gcgcaaacgg cgattaaaga ctgggtgaat gcctataact
     4441 cgctaataga taccttcagc agcctgacca aatacaccgc cgtagatgcg ggagctgata
     4501 gccaaagctc tagcaatggc gcactgctcg gcgactccac gctgcggacg attcagacgc
     4561 agttgaagtc gatgctgagt aataccgtca gttcttccag ctataaaacg ttggcgcaga
     4621 ttggtatcac gaccgatccc agcgatggca aactggaact ggatgccgac aaactcaccg
     4681 ctgcactgaa aaaagatgcc agcggcgtag gtgcattgat tgttggcgat ggtaaaaaaa
     4741 ccggcatcac aaccaccatc ggcagcaacc tgaccagttg gctttcgaca acgggcatta
     4801 ttaaagccgc taccgatggc gttagtaaga ctctgaataa attaactaaa gactacaacg
     4861 ccgccagcga tcgcattgat gcgcaggtcg cgcgctacaa agaacaattt acccaactgg
     4921 acgttttaat gacctcgtta aacagcacca gcagctactt aacgcagcag ttcgaaaaca
     4981 acagtaattc caagtaatca atattcatcg ggagacaggt catgtacgcg gcaaaaggca
     5041 cccaggccta tgcacaaatt ggcgtcgaaa gcgccgtaat gagcgccagc cagcagcagc
     5101 tggtcaccat gctatttgat ggagtgctga gcgcactggt tagagcgcgc ctgtttatgc
     5161 aggacaacaa tcagcaaggc aaaggcgtct ctttgtcaaa agcgatcaac atcattgaga
     5221 acggactgcg ggtgagtctt gatgaagata gcaaagacga attaacccaa aacttgattg
     5281 ctctttatag ctatatggtc aggcgtttgc tgcaagccaa tttacgcaac gatgtctccg
     5341 cagtcgaaga agtggaagca ttaatgcgca atattgccga tgcctggaaa gagtcgttac
     5401 tctccccttc tttgattcag gacccagtct gatgaaccat gcaccgcatt tgtatttcgc
     5461 ctggcaacaa ctcgtcgaaa aaagccagct catgttacgc ctggcaacgg aagaacaatg
     5521 ggacgaactc atcgccagcg aaatggcgta tgtgaatgcg gtgcaggaga tagcacacct
     5581 gactgaagag gttgccccgt ccaccacgat gcaggagcag ctccgcccga tgctgcgcct
     5641 gattctcgac aacgaaagca aggtaaagca gttattacag attcgtatgg atgaactggc
     5701 gaaactggtc ggtcagtcat cggtgcaaaa atcggtgtta agtgcctatg gcgatcaggg
     5761 cggctttgtg ctggctccgc aagataactt ctcgtgaatc ttaacgagct aatggttcgc
     5821 gaataatccg attacggcta cgcttctaat gttccccttg aatggagtcg aagaatgcgt
     5881 aatcccacgc tgttacaatg ttttcactgg tattacccgg aaggcggtaa gctctggcct
     5941 gaactggccg agcgcgccga cggttttaat gatattggta tcaatatggt ctggttgccg
     6001 cccgcctata aaggcgcatc gggcgggtat tcggtcggct acgactccta tgatttattt
     6061 gatttaggtg agtttgatca gaaaggcagc atccctacta aatatggcga taaagcacaa
     6121 ctgctggccg ccattgatgc tctgaaacgt aatgacattg cggtgctgtt ggacgtggta
     6181 gtcaaccaca aaatgggcgc ggatgaaaaa gaagctattc gcgtgcagcg tgtaaatgct
     6241 gacgaccgta cgcaaattga tgaagaaatc attgaatgcg aaggctggac gcgttacacc
     6301 ttccccgccc gtgccgggca atactcacag tttatctggg atttcaaatg ttttagcggt
     6361 atcgaccata tcgaaaaccc tgatgaagat ggcatattta aaattgttaa cgactacacc
     6421 ggcgaaggct ggaacgatca ggttgatgat gaattaggta atttcgatta tctgatgggc
     6481 gagaatatcg attttcgcaa tcatgccgtg acggaagaga ttaaatactg ggcgcgctgg
     6541 gtgatggaac aaacgcaatg cgacggtttt cgtcttgatg cggtcaaaca tattccggcg
     6601 tggttttata aagagtggat cgaacacgta caggaagttg cgccaaagcc gctgtttatt
     6661 gtggcagagt actggtcgca tgaagtcgat aaactgcaaa cgtatattga tcaggtggag
     6721 ggcaaaacca tgctgttcga tgcgccgctg cagatgaaat tccatgaagc atcgcgcatg
     6781 gggcgcgact acgacatgac gcagattttc acgggtacat tagtggaagc cgatcctttt
     6841 cacgccgtaa ccctcgttgc caaccatgac acccaaccgt tgcaagccct cgaagcgcca
     6901 gtcgaaccgt ggtttaaacc gctggcgtat gccttaattt tgttgcggga aaatggcgtt
     6961 ccttcggtat tctatccgga cctctacggt gcgcattacg aagatgtcgg tggtgacggg
     7021 caaacctatc cgatagatat gccaataatc gaacagcttg atgagttaat tctcgcccgt
     7081 cagcgtttcg cccacggtgt acagacatta tttttcgacc atccgaactg cattgccttt
     7141 agccgcagtg gcactgacga atatcccggc tgcgtggtgg tcatgtcgaa cggggatgat
     7201 ggcgaaaaaa ccattaatct gggagagaat tacggcaata aaacctggcg tgattttctg
     7261 gggaaccggc aagagagcgt agtaaccgac gaaaacggtg aagcgacctt cttttgcaac
     7321 ggcggcagcg tcagcgtgtg ggttatcgaa gaggtgattt aaattcatcc ccggcggcaa
     7381 gccggggaga tttcattacg gcagtggcgt cggtaacggc gctttatcca gcgcagcggc
     7441 acactctgcc gtcgggcgat ccacacgctc catcgtcata ccatcgtact caatggtgtt
     7501 accgtcacgc tcaacctcgt acagctcacg ttttacggta acgttagtga gatcatctga
     7561 catcaatgtc aacttgcccg gcacggcaat cacccgctgc cactgacggc aatccagggt
     7621 atcgccctct ttagtgacaa tcaggctgcc tatcgcttcc ggactgacca gcgcacgttg
     7681 cggccctttg gtctgccagt agcccgccag ccagtccggc gcgggggttt tcacgacatt
     7741 gttatagttt tcgacttcgg cacagcccgc cagcaacatg agcgcgcctg caattgcgag
     7801 ttttttcatc attcgtcctg catgagaaga aaagaggatt gtggcattaa agccctgatg
     7861 tcgccagcct ttccaggttc agagagaaat ttgatctaac tattattttt gtgaattatt
     7921 accccgaaaa taaatttgca tgatgtatga ttcgcgactc ttgtttcaaa ccttctgagt
     7981 tcagaggcta cattcatgtc atggcagcaa ttcaaacacg cctggttgat taaattctgg
     8041 gcacccatcc ctgcggtcat cgcggcgggt attctctcca cttactattt tggcattact
     8101 ggcacctttt gggctgtcac gggtgaattt acccgttggg gcggccagct cctgcagctg
     8161 tttggcgtcc atgctgaaga gtggggttat tttaaaatta tccatctgga aggatcgcca
     8221 ttaacccgca tcgacgggat gatgatcctc ggcatgtttg gcggctgctt tgccgcagcg
     8281 ctgtgggcca acaatgtcaa actacgcatg ccgcgcagcc gtatccgcat tatgcaggcc
     8341 attattggcg gtattatcgc cggttttggc gcgcgtctgg caatgggctg taacctggcg
     8401 gcgttcttta ccggcattcc tcagttctcg ctgcatgcct ggttctttgc catcgccact
     8461 gccattggtt catggtttgg cgcgcgcttt accctgctgc ccatcttccg tattcccgtg
     8521 aaaatgcaga aagtttctgc cgcctcaccg ctgacgcaaa aaccggatca ggcgcggcgt
     8581 cgttttcgtc tcgggatgct ggtctttttc ggcatgctgg gctgggcgct gctcacggcg
     8641 atgaaccaac ccaaactggg gctggcaatg ctgtttggcg tcggctttgg tttactgatt
     8701 gaacgtgcgc aaatctgctt tacttcggcg ttccgcgata tgtggatcac cggacgtacc
     8761 cacatggcga aagcaatcat tattggtatg gcggtgagtg ccatcgggat cttcagttac
     8821 gtacagttag gtgttgaacc caaaatcatg tgggcgggac caaacgcggt aattggtggt
     8881 ttactgtttg gttttggcat cgtgctggca ggcggctgcg aaaccggttg gatgtaccgc
     8941 gcggtagaag gtcaggtgca ctactggtgg gtcggtctgg gcaatgtgat cggctcaacc
     9001 attctggcgt attactggga tgatttcgct ccggcgctgg ccaccgactg ggacaaaatc
     9061 aacctgctga aaacctttgg cccgatgggt ggcctgctgg tgacatattt gctgttgttt
     9121 actgcgctga tgttgattat cggctgggaa aaacgcttct tccgccgtgc ggcaccgcag
     9181 actgctaagg agatcgcatg aaaaatatca ttcctgatta ccgtcttgat atggtgggtg
     9241 aaccctgccc ttatccggca gtcgcaaccc ttgaggcgat gccgcagtta aaaaaaggtg
     9301 agatcctgga agtggtgagc gactgtccgc agtcgatcaa taatattcca ctggatgctc
     9361 gtaatcacgg ctatacggtg ctggatattc agcaagacgg gccgaccatt cgttatttaa
     9421 ttcagaagta atccctcatt cccgctgtgg ccaacagcgg gaatatcgtt gcctctgtac
     9481 cacatagatt ttacccgccc cctctcctat tcttttcagt gtgctctcag gaggttgcta
     9541 tgtgtggacg ctttgcccaa tcccaaacgc gtgaagatta ccttgcgctt ctcgcggaag
     9601 atattgaacg cgatattccc tatgatcccg aacccattgg cagatacaac gtcgcgccgg
     9661 gaaccaaagt tcttctgctc agtgaacgtg atgaacacct tcatctggat ccggttttct
     9721 ggggatatgc tcccggatgg tgggataaac cgccgctgat taacgcccgc gtagaaactg
     9781 cggccaccag tcgtatgttt aaaccgctct ggcaacatgg tcgggcaatc tgttttgccg
     9841 atggctggtt tgagtggaaa aaagaaggcg acaaaaaaca gccttatttt atctatcgtg
     9901 ctgacggaca acctgttttt atggccgcga taggtagcac accgtttgag cgcggtgacg
     9961 aagccgaagg atttttaatt gtcactgcag cagcagacca gggtctggta gatattcatg
    10021 accgccgccc gctggtactg tcgccagaag ctgcgcggga atggatgcgg caagagattg
    10081 gcggtaaaga agcatcagaa attgctacca acggctgtgt gccagcaaac cagttcacct
    10141 ggcacccggt atcgcgcgcg gtaggtaatg tcaaaaacca gggcgcggag ttaattcaac
    10201 ctgtttgata agccaggaga ctattgatca ataatactgc gtcataagaa atctctatta
    10261 gacaaagtag acgctccttc cacatgcgcc acaagaaacc tctattccag tgacacaatt
    10321 acgcctgatt atttccctag cccggaatat gaataaaaac atcaacaaag attaaattat
    10381 tcaaacgtta ctgttgcgtc tgcggtcgta acaacatccg acgtggtgat gtgtatcaaa
    10441 tgaggcctct gatgatcaga gggtttatcg cgtatacgga tcgtggatgg cagaaaactt
    10501 tcagaatcag gtttccattt taaaccagaa attgagtgag tttgccccat ccatgcccca
    10561 cgcggtgaga tcggatgtaa ttaacaacag gttacaaaac ctacacctgc atgctcatca
    10621 cttcctgata cgccgccacc agcttattac gcacctgaat ccccatttgc atagaaactg
    10681 aggctttttg catatcggtc atcacatcgt ttaacgccac gccgggttca ccgagagtga
    10741 atttttctgc ctgcgtgcgg gcagctgttt gtgtatcact aatgcgatcg agcgcggcgt
    10801 gcagctgccc ggcaaaacta atggtcggtt gcggcagtga ttcctgcgca cgcgcactca
    10861 tcgccgtagc ctgtaactgg ctgataaccc cttcaatccc ctgtatcgct gacattctcg
    10921 tctcccggat aatttctggt agcaaagcct accagtaagt caataagaca aaggcgctaa
    10981 ataacaacaa aaaaacgggt ttattggcgg atagaaaaaa acgaaagcac aaataatggg
    11041 agcgtcaatt tttcgagttt gctgacccgg gagtgagtct tgttccactt tgccaataac
    11101 gccgtccata atcagccacg aggtgcgcga tgaatgcgac tgcagcccag acaaaatctc
    11161 ttgagtggct taatcgcctg cgtgcgaatc cgaaaattcc attgattgtt gccggttccg
    11221 cggcagtggc ggtcatggtc gcactgatcc tgtgggcgaa agcccccgac taccgcacat
    11281 tattcagcaa tctttccgat caggatggtg gcgcaattgt cagccaactg acgcaaatga
    11341 atattcctta ccgcttcagc gaagccagcg gcgctattga agttccggca gataaagttc
    11401 acgaactgcg tctgcgcctg gcacaacaag gtttgcccaa aggcggcgcg gtcggtttcg
    11461 aactactcga tcaggaaaag tttggtatca gccagttcag cgaacaggtg aattatcagc
    11521 gggcgctgga aggcgagctt tctcgtacca tcgaaactat cggcccggta aaaggggcgc
    11581 gcgtacatct ggcaatgccg aaaccgtctt tattcgtccg tgaacaaaaa tccccttctg
    11641 catcggtgac ggtaaatctg ttacccggcc gcgcactcga tgaagggcaa attagcgcca
    11701 ttgtacatct ggtttccagc gcggttgctg gtctgccgcc ggggaacgtc acgctggtgg
    11761 atcagggtgg acatctgtta acccagttca acaccagcgg gcgcgatctt aatgacgctc
    11821 agttgaaata tgccagcgat gtcgaaggcc gtattcagcg gcgtattgaa gcgatcctgt
    11881 cgcctattgt tggtaacggt aatattcacg cccaggtcac ggcgcagctg gacttcgcca
    11941 gtaaagaaca aacggaagaa cagtatcgcc ctaacggtga tgaatctcat gcggcgcttc
    12001 gttcacgcca gcttaatgag agcgagcaaa gcggttccgg ttatccgggc ggcgtaccgg
    12061 gggcgttgtc gaatcaaccg gcacctgcga ataacgcgcc aatcagcacg cctccggcaa
    12121 atcaaaataa ccgccagcag caggcgagca ccaccagcaa tagcgggccg cgtagcacac
    12181 agcggaatga aaccagtaac tacgaagtcg atcgcaccat tcgtcatacc aaaatgaacg
    12241 tgggcgatgt gcaacgtctg tcagtcgcgg tagtggtgaa ttacaaaacc ttgccagacg
    12301 gtaaaccatt gcctctcagc aacgaacaga tgaagcaaat tgaagatctg acccgcgagg
    12361 cgatgggctt ttctgaaaaa cgcggtgact cgctcaatgt cgttaactcg ccgttcaata
    12421 gcagtgacga aagcggcgga gaactgccgt tctggcaaca gcaagcgttt atcgatcagt
    12481 tgctggctgc cggtcgctgg ttgctggtac tgctggtggc gtggctgctg tggcggaaag
    12541 cggtacgccc gcagttaaca cgtcgcgccg aggcgatgaa agctgtacag caacaggcgc
    12601 aggcccgtga ggaagtggaa gatgcggtgg aagtccgcct gagcaaagac gaacaactcc
    12661 aacaacgacg cgctaaccaa cgtctggggg cagaagtcat gagccagcgt atccgtgaaa
    12721 tgtctgataa cgatccgcgc gtggtggcgc tggtcattcg ccagtggata aataacgatc
    12781 atgagtaacc tgacaggcac cgataaaagc gtcatcctgc tgatgaccat tggcgaagac
    12841 cgggcggcag aggtgttcaa gcacctctcc cagcgcgaag tgcaaaccct tagcgctgca
    12901 atggcgaacg tcacgcagat ctccaacaag cagctaaccg atgtgctggc ggaatttgag
    12961 caagaagctg aacagtttgc cgcactgaat atcaacgcca acgattatct gcgttcggta
    13021 ttggtcaaag ctctgggtga agaacgtgcc gccagcctgc tggaagatat tctcgaaact
    13081 cgcgataccg ccagcggtat tgaaacgctc aactttatgg agccgcagag cgccgccgat
    13141 ctgattcgcg atgagcatcc gcaaattatc gccaccattc tggtgcatct gaagcgcgcg
    13201 caggccgccg atattctggc gttgttcgat gaacgtctgc gccacgacgt gatgttgcgt
    13261 atcgccacct ttggcggcgt gcagccagcc gcgctggcgg aactgaccga agtactgaat
    13321 ggcttgctcg acggtcagaa tctcaagcgc agcaaaatgg gcggcgtgag aacagcagcc
    13381 gaaattatca acctgatgaa aactcagcag gaagaagccg ttattaccgc cgtgcgcgaa
    13441 ttcgacggcg agctggcgca aaaaattatc gacgagatgt tcctgttcga aaatctggtg
    13501 gatgtcgacg atcgcagcat tcagcgtctg ttgcaggaag tggattccga atcgctgttg
    13561 atcgcgctga aaggggccga gcagccactg cgcgagaaat tcctgcgcaa tatgtcgcag
    13621 cgtgccgccg atattctgcg cgacgatctc gccaaccgtg gtccggtgcg tctgtcgcag
    13681 gtggaaaacg aacagaaagc gattctgctg attgtgcgcc gccttgccga aactggcgag
    13741 atggtaattg gcagcggcga ggatacctat gtctgataat ctgccgtgga aaacctggac
    13801 gccggacgat ctcgcgccac cacaggcaga gtttgtgccc atggtcgagc cggaagaaac
    13861 catcattgaa gaggccgaac ccagccttga gcagcaactg gcgcaactgc aaatgcaggc
    13921 ccatgagcaa ggttatcagg cggggattgc cgaaggtcgc cagcaaggtc atgagcaggg
    13981 ctatcaggaa ggactggccc gggggctgga gcaaggtctg gcagaggcga agtctcaaca
    14041 agcgccaatt catgcccgga tgcagcaact ggtcagcgaa tttcaaacta cccttgatgc
    14101 gcttgatagt gtgattgctt cgcgcctgat gcagatggcg ctggaggcgg cacgtcaggt
    14161 gatcggtcag acgccaacag tggataactc ggcactgatc aaacagatcc aacagttgtt
    14221 gcagcaagaa ccgttattca gcggtaaacc acagctgcgc gtgcacccgg atgatctgca
    14281 acgtgtggat gatatgctcg gcgcaacctt aagtttgcat ggctggcgct tgcggggcga
    14341 tcccacactc catcctggcg gctgtaaagt ctccgccgat gaaggcgatc tcgacgccag
    14401 tgtcgccact cgctggcaag aactctgccg tctggcagca ccaggagtgg tgtaatgacc
    14461 acgcgcctga ctcgctggct aaccacgctg gataactttg aagccaaaat ggcgcagttg
    14521 cctgcggtac gtcgctatgg gcgattaacc cgcgctaccg ggctggtgct ggaagccacc
    14581 ggattacaat tgccgctcgg cgcaacctgt gtcattgaac gccagaacgg cagcgaaacg
    14641 cacgaagtag aaagcgaagt cgttggcttt aacggtcaac ggctgttttt aatgccgctg
    14701 gaggaagtgg aaggtgtcct gcccggcgcg cgggtttatg ccaaaaacat ttcggctgaa
    14761 ggactgcaaa gcggcaagca gttgccgctc ggtccggcgt tattaggtcg cgttctggac
    14821 ggcagcggta agccgctcga tggcctgccc tcccccgata cgacggaaac cggtgcgctg
    14881 attaccccgc catttaaccc gttgcaacgt acaccgattg aacatgtgct ggacaccggc
    14941 gtgcgcccaa tcaatgccct gcttaccgtt gggcgtgggc agcgtatggg gctgtttgcc
    15001 gggtccggcg ttggtaaaag tgtgctgctg gggatgatgg cacgttacac ccgcgccgat
    15061 gtcattgtcg tgggtttgat tggtgaacgt gggcgcgaag taaaagattt tattgagaat
    15121 atcctcggtg ccgaagggcg tgcacgctcc gtggtgattg ccgctccggc ggatgtctct
    15181 ccgcttctgc gaatgcaagg tgccgcctat gccacgcgca ttgccgaaga ttttcgcgat
    15241 cgtggtcagc atgtgttgct gattatggat tccctcaccc gctacgcgat ggcccagcgt
    15301 gaaattgcgc tggcgattgg cgaaccaccc gccaccaaag gttatccccc gtcggtgttt
    15361 gccaaattac cggcactggt cgagcgtgcc ggaaatggca ttagcggcgg cggatcgatt
    15421 accgcgtttt ataccgtgct caccgagggc gatgaccagc aggaccccat tgccgactcc
    15481 gcgcgggcaa tcctcgacgg tcacattgtg ctgtctcgcc gactggcgga agccgggcac
    15541 tatccggcta tcgatattga agcgtcgatc agccgcgcaa tgacggcgtt gatcagcgag
    15601 caacattacg cgcgagtgcg caccttcaaa cagctgttgt cgagttttca gcgtaaccga
    15661 gatctggtta gcgtcggcgc gtatgccaaa ggcagcgatc cgatgctcga taaagccatc
    15721 gccctgtggc cgcagctgga gggctatttg caacaaggca tttttgaacg cgcggactgg
    15781 gaagcgtctc tccaggggct ggagcgtatt ttcccgacag tgtcataacc caggagataa
    15841 cggcagatgg cagaacatgg cgcgctggcg accctgaaag atctggcaga aaaagaggta
    15901 gaggatgccg cgcgcctgct gggtgaaatg cgtcgcgggt gtcagcaggc ggaagaacag
    15961 ctcaaaatgc tgatcgatta tcagaatgaa tatcgcaata acctcaacag cgatatgagt
    16021 gccgggatga ccagcaaccg ctggatcaac tatcagcagt ttatccagac gctggaaaaa
    16081 gccattactc agcatcgcca gcaacttaat cagtggacgc agaaagttga cattgccctg
    16141 aacagctggc gagaaaagaa acaacgtttg caggcctggc agacactgca ggaacggcaa
    16201 tccacggcgg cactgcttgc agaaaaccgc ctcgatcaga aaaagatgga tgagttcgcc
    16261 cagcgcgccg ccatgaggaa acctgaatga ttcgcttagc gcccttaatt accgccgacg
    16321 ttgacaccac cacattgcct ggcggcaaag ccagcgatgc tgcacaagat tttctcgcgt
    16381 tgttgagcga agcattagca ggcgagacaa ctaccgacaa agcggccccc cagttgctgg
    16441 tggcaacaga taagcccacg acaaaaggcg agccgctggt cagcgagatt cttgccgatg
    16501 cgcaacaagc ggatttactg atccctgtgg atgaaacacc gcctgtcatc aacgacgaac
    16561 aatccacatc aacaccatta accaccgctc aaacgatgac gttggctgcg gtggctggca
    16621 acaatacggc aaaagacgaa aaagcggatg atctgaatga agacgtcacc gcaagcctga
    16681 gcgccctttt tgcgatgttg ccgggttttg acaatacgcc caaagtgact gatgtgccgt
    16741 caaccgtgtt accggcagag aaaccaacgc tcttcacaaa actgacttct gcgcaactca
    16801 caacagcaca gcctgatgat gcccccggca cgccagctca gccattaaca ccgctggtag
    16861 cagaagccca gagtaaagcg gaagtcatca gcacaccttc accggtgacc gctgccgcca
    16921 gcccgctaat cactccacac cagacacagc cactgcccac cgtcgccgcg cctgtgttga
    16981 gtgcaccgct gggttctcac gaatggcaac aatcattaag ccagcatatt tcgctgttca
    17041 cccgccaggg gcaacaaagt gcagagttgc gtctgcaccc gcaggattta ggtgaagtgc
    17101 aaatctccct caaagtggat gataaccagg cgcaaatcca gatggtttca ccgcatcaac
    17161 acgtacgcgc cgccctggaa gcagcgcttc cggtactgcg aacgcagctg gccgaaagtg
    17221 gcattcagtt agggcaaagc aacatcagtg gcgaaagctt tagtggtcag cagcaggccg
    17281 cttcccaaca acagcaaagc caacgcacag taaaccatga acctctggcg ggggaagacg
    17341 acgatacgct tccggttccc gtctctttac aagggcgtgt aacaggcaac agcggcgttg
    17401 atattttcgc ctaacgtcag aggtagcacc gtaatccgcg tcttttcccc gctttgttgc
    17461 gctcaagacg caggataatt agccgataag cagtagcgac acaggaagac cgcaacacat
    17521 gactgattac gcgataagca agaaaagcaa gcgatcgctt tggatcccga ttctggtatt
    17581 cattaccctc gcggcctgtg ccagcgcagg ttacagctac tggcattcgc atcaggttgc
    17641 cgctgacgac aaagcgcagc aacgcgtcgt accctccccg gtcttctacg cgctggatac
    17701 cttcacggtc aatttgggcg atgcggatcg cgtgctttat atcggcataa ccctgcgcct
    17761 gaaagatgaa gctacccgct cgcggctgag tgagtatttg ccggaagtcc gtagccgttt
    17821 gctgttactg ttttcgcgtc aggatgctgc cgtactggcg acagaagaag gcaagaaaaa
    17881 cctgattgcc gagattaaaa ccacgctttc caccccgctt gttgccgggc aaccgaaaca
    17941 ggatgtcacc gacgtgctgt ataccgcttt tattctgcga taacgacatg ggcgatagta
    18001 ttctttctca agctgaaatt gatgcgctgt taaatggtga cagcgaagtc aaagacgaac
    18061 cgacagccag tgttagcggc gaaagtgaca ttcgtccgta cgatccgaat acccaacgac
    18121 gggttgtgcg cgaacgtttg caggcgctgg aaatcattaa tgagcgcttt gcccgccatt
    18181 ttcgtatggg gctgttcaac ctgctgcgtc gtagcccgga tataaccgtc ggggccatcc
    18241 gcattcagcc gtaccatgaa tttgcccgca acctgccggt gccgaccaac ctgaacctta
    18301 tccatctgaa accgctgcgc ggcacagggc tggtggtgtt ttcaccgagt ctggtgttta
    18361 tcgccgtgga taacctgttt ggcggcgatg gacgcttccc gaccaaagtg gaaggtcgcg
    18421 agtttaccca taccgaacag cgcgtcatca accgcatgtt aaagctggcg cttgaaggct
    18481 atagcgacgc ctggaaggcg attaatccgc tggaagttga gtacgtgcgt tcggaaatgc
    18541 aggtgaaatt taccaatatc accacctcgc cgaacgacat tgtggttaac acgccgttcc
    18601 atgtggagat tggcaacctg accggcgaat ttaatatctg tctgccattc agcatgatcg
    18661 agccgctacg ggaattgttg gttaacccgc cgctggaaaa ctcgcgtaat gaagatcaga
    18721 actggcgcga taacctggtg cgccaggtgc agcattcaca gctggagctg gtcgccaact
    18781 ttgccgatat ctcgctacgc ctgtcgcaga ttttaaaact gaaacccggc gacgtcctgc
    18841 cgatagaaaa acccgatcgc atcatcgccc atgttgacgg cgtcccggtg ctgaccagtc
    18901 agtacggcac tctcaacggt cagtatgcgt tacggataga acatttgatt aacccgattt
    18961 taaattctct gaacgaggaa cagcccaaat gagtgacatg aataatccgg ccgatgacaa
    19021 caacggcgca atggacgatc tgtgggctga agcgttgagc gaacaaaaat caaccagcag
    19081 caaaagcgct gccgacgcgg tgttccagca atttggcggt ggtgatgtca gcggaacgtt
    19141 gcaggatatc gacctgataa tggatattcc ggtcaagctg accgtcgagc tgggccgtac
    19201 gcggatgacc atcaaagagc tgttgcgtct gacgcaaggg tccgtcgtgg cgctggacgg
    19261 tctggcgggc gaaccactgg atattctgat caacggttat ttaatcgccc agggcgaagt
    19321 ggtggtcgtt gccgataaat atggcgtgcg gatcaccgat atcattactc cgtctgagcg
    19381 aatgcgtcgc ctgagccgtt agtgatgaat aaccacgcta ctgtgcaatc ttccacgccg
    19441 gtttctgctg cgccactgct gcaggtcagc ggcgcactca tcgccattat tgccctgatc
    19501 ctcgctgctg cctggctggt aaaacggttg ggatttgccc cgaaacgcac tggcgttaac
    19561 ggtctgaaaa ttagcgccag tgcttcgctg ggcgcgcgtg aacgggttgt ggtggtcgat
    19621 gtggaagatg cacggctggt gctcggcgtt accgcagggc aaatcaatct gctgcataaa
    19681 cttccccctt cagcaccaac agaagagata ccgcagaccg attttcagtc ggtcatgaaa
    19741 aatttgctta agcgtagtgg gagatcctga tgcgtcgttt gttgtctgtc gcacctgtcc
    19801 ttctctggct ggttacgccc ctcgccttcg cgcaactgcc gggtatcacc agccagccgc
    19861 tgcctggcgg tggacaaagc tggtcgctcc cggtgcagac gctggtgttc atcacctcgt
    19921 tgacgtttat tccggcaatt ttactgatga tgaccagttt cacccgcatc atcattgttt
    19981 ttggtttatt gcgtaacgcg ctgggaacgc cctccgcgcc acctaaccag gtattgctgg
    20041 ggctggcact atttttgacc ttttttatta tgtcaccggt gatcgataaa atttatgtcg
    20101 atgcgtacca gccattcagc gaagagaaaa tatcaatgca ggaggcgctg gaaaaagggg
    20161 cgcagccgct acgtgagttt atgctgcgtc agacccgtga ggcagattta gggttgtttg
    20221 ccagactagc gaataccggc ccgttgcagg gacctgaagc cgtgccgatg cgcattttgc
    20281 tcccggccta cgtgaccagc gagttgaaaa ccgcatttca gataggcttc acgattttca
    20341 ttcctttttt gattatcgac ctggtgattg ccagcgtgtt gatggcattg gggatgatga
    20401 tggtcccccc cgccaccatt gctctgccct ttaaactgat gctgtttgta ctggtggatg
    20461 gctggcaatt gctggtcggt tcgctggcgc agagctttta cagctagaga ggcaaaatga
    20521 cacctgaatc ggtcatgatg atggggactg aagcgatgaa agtcgcgctg gcactggctg
    20581 ccccgctgtt gctggtggcg ctggtcacgg gccttatcat cagtattttg caggccgcca
    20641 cgcagatcaa cgaaatgacg ctgtcgttta ttccaaaaat catcgccgta tttattgcca
    20701 ttattattgc cggaccgtgg atgctcaatc tgttgctgga ttacgtccgc accttgttca
    20761 ctaacctgcc gtatatcatc gggtagcccg tacaatgatg caggtgacaa gcgatcaatg
    20821 gctttcctgg ctaagtctgt acttctggcc gttactgcgc gtgctggcgc tcatttctac
    20881 cgcgccaatt ctgagcgaac gcagcgtgcc gaaacgggta aaactgggtc tggcaatgat
    20941 gatcacgttc gctattgccc catcattacc tgccaacgat gttcctgttt tttcgttctt
    21001 tgctctgtgg ctggccgtgc agcagatcct gatcggcatt gcgcttggtt ttaccatgca
    21061 atttgccttt gccgctgtgc gaaccgctgg cgaaattatc ggtctgcaaa tggggctgtc
    21121 atttgcgacg tttgtcgatc cggccagcca tctcaatatg cctgttttag cgcgtatcat
    21181 ggatatgctg gcgttactac tgttcctgac atttaacggt catttatggt tgatttcact
    21241 gctggtcgat acctttcaca ccctgccaat tggtggcgaa ccgttgaaca gcaatgcgtt
    21301 tctggcactc accaaagcag ggagtttgat tttccttaac gggctgatgc tggcgttacc
    21361 gctcattact ctgctgctga cactgaatct ggcattaggt ttacttaatc gtatggcccc
    21421 gcaattatcc atttttgtta ttggatttcc attaactctg actgtcggta tctctttaat
    21481 ggcggcatta atgccgttaa ttgcaccttt ttgcgaacat ttattcagtg agatgtttaa
    21541 tttgctggct gatattatta gtgaattgcc attaatataa ttccgtaacg tttatcatgt
    21601 tatcctaagg attatccgaa aaataatacc tacgaacatc ttccaggata ctcctgcggc
    21661 gaaatatttg ttttaaggtc actcacatat cgcaacattt actttacttt aagacaattc
    21721 caggcaaatt atacaacact ttacgggata gtaagtccgc ctgaaaaatc gcgagagtgg
    21781 cgcattaggt gacccatgtt gttccgttta gtcatgatga aatattcagg taaggggaat
    21841 tatcgttacg cattgagtga gggtatgcca tgtcaacgat tattatggat ttatgtagtt
    21901 acacccgact aggtttaacc gggtatctgt tgagtagagg ggttaaaaaa agagaaatca
    21961 acgacattga aaccgttgat gaccttgcca tagcttgtga ttcacagcgc ccttcagtgg
    22021 tgtttattaa tgaggactgt ttcatccatg atgcttctaa cagtcagcgc atcaagcaca
    22081 tcattaatca acatcccaat acgttattta tcgtttttat ggcaattgcc aatgttcatt
    22141 ttgatgaata tctattggtc agaaaaaatt tattgatcag ttctaaatcg attaaaccgg
    22201 aatctctcga cgatatcctt ggcgatattc tgaaaaaaga gacaacgata acctcttttt
    22261 taaatatgcc gacgttatca ttgagccgaa ccgaatcgag tatgttgcga atgtggatgg
    22321 caggtcaggg aaccattcaa atctctgacc aaatgaatat caaagccaag accgtttcat
    22381 cgcataaagg taatattaaa cgtaagatca aaacgcataa taaacaggtt atctaccatg
    22441 tcgtccgact gacggataat gtgactaatg gtatttttgt caacatgcgc taacacattc
    22501 tgactggtgg tttcccacca gtcaggctga ataagattac tctgctttct ccacaaagat
    22561 accgtcctga tgccctgctt cattaaagaa ccagatgccg agcgggtagt cttccagcga
    22621 aaccaggtac attgtgcctt cactaaactc ctcaactgcc agtaccacgc caggacgacg
    22681 cggaccgcca tccgttttga ctgttacccg atcattcacc ttcatcgttt tcctcctgtg
    22741 gctttgtgcc agtgtagaac aatttcgttt ttctggcagc gccaggcgcg cgcgagtgct
    22801 gattttctcg acggtctata cttaagagat gccaggcgga cttaacgact ggcggcaaca
    22861 acagagtaac ggttgcgagg aaagatgatg aaaaccgcaa aagagtacag cgataccgca
    22921 aaacgtgagg tcagcgtcga tgtcgatgcc ctgctggcgg cgatcaatga aattagcgaa
    22981 agcgaagttc atcgcagcca gaacgattct gaacacgtta gcgtcgatgg acgtgaatat
    23041 catacatggc gtgaattggc ggatgccttc gaactggata ttcatgactt cagcgtctct
    23101 gaagtgaatc gttgaatgca caataaaaaa atcccgaccc tgagggggtc gggatgaaac
    23161 ttgcttaagc aagaagcact taaaaaattc gttacaccag gaaatctgat gtgttcatca
    23221 ccttatccgc aatttttttc gctgacaaga aaatattcgc catatgaatg attaacgcta
    23281 cttatgaata gaaatgtgac gcacgtcacc ccttggtggc tctggcgtca gcgggatcgc
    23341 tcccgaaaaa atcatctttg ataatttgtg ctgttttgag aatcatcctg gtaaggggag
    23401 aactgcgcga ccatgttttc aattcaacaa ccactactgg tttttagcga tcttgatggc
    23461 accctgctgg acagtcatag ttatgactgg caaccggctg ccccctggct cagccgttta
    23521 cgcgaagcga atgttcccgt cattctctgt agcagtaaaa cttcagcgga aatgctgtac
    23581 ttgcaaaaaa cgttggggct acaagggtta ccgctgattg ccgaaaatgg cgcagtgatc
    23641 cagcttgctg aacaatggca ggatatagac ggttttccac gcatcatctc aggtattagc
    23701 catggcgaaa tcagccaggt tttaaatacg ctacgcgaga aagaacattt taaattcacg
    23761 actttcgatg atgtcgacga tgcaaccatc gccgaatgga cgggattaag ccgtagccag
    23821 gcggcgctga cgcagctgca tgaggcgtcg gtaacgctaa tctggcgcga cagtgacgag
    23881 cgtatggcac aatttaccgc tcgtctgaac gaactgggct tacagtttat gcagggtgcg
    23941 cgcttctggc acgtactgga tgcctctgcc ggaaaagatc aggctgccaa ctggattatc
    24001 gcgacctatc aacaattgtc aggcaaacgc ccaaccacac ttggcctggg cgatgggcca
    24061 aacgatgcgc ccttactgga ggtaatggat tacgcggtga ttgtgaaagg gctaaaccgt
    24121 gaaggggtgc atctgcatga tgaggatccg gcccgcgtct ggcgaacgca gcgtgaagga
    24181 ccggaaggct ggggtgaagg gctggaccat tttttctccg cccgttaagc gttatcgctc
    24241 gcgcataccc gattacgccc ggcctgttta gcgagataaa gtcgacggtc agccagtgac
    24301 tggagttgtt caaaatcata atcaccggtt tcctcgctgc tacttacccc cagcgaggca
    24361 ctgatgcgta tcgtcgtact cttagcaatc aacatctctt tttcatttaa cttcaggcga
    24421 atacgttctg cgacttccgc agcctccgtc agactcgcgc ctggcagaat cacacaaaac
    24481 tcctcaccac cgacccgccc ggcaacgtcc tgcgcacgca aggaactgct aattaatccg
    24541 gcagcatgag aaagaacacg gtcgcccgcc tgatgaccaa agcggtcatt aatcgcttta
    24601 aaatggtcaa gatcgacctg aatgacagaa aaaggatgtt ggtgcgtctg atacaattta
    24661 gcgagcggac gggctttttc gaacagtgcg ccacggttat ataaacgcgt taaggtgtcg
    24721 tgccacgcct gccactgcaa cgagctttgc agaacataca tgttgctaac catccggcga
    24781 atcacatacc aggagatgag taacatggtg gtaaagagcg cccacagcag ggttaatgca
    24841 atgctgatac tgccgaaatc gccgcgcacg ccttcgctta acgtatggac gcgcaccagc
    24901 acaccgtcga aatggtccag acgttcccag ctaacatagc gactgtccat acgaatgccg
    24961 ccccgcgtgt catgttccat cgcctgcgcc agcaaggcca gttcacgagg atcaaaaata
    25021 ttccctgttg gatggtcagg attggaagag gtcaaaaatc tcagcttact gtcatagagc
    25081 tgatactcac catcgaggtt tttatcgatg gcgtttctta aaaattgctg catggtacgc
    25141 acgggaatac tcatccccag cacgccatac cagtagttat tactgtctac tggaacactg
    25201 acggtaacct gcggttcagt attgctggcg tgttccggtt gcgaagtaaa ccagcgtact
    25261 gcgcggtgac gattttctcg ttgcgaatgg ccgataaacc agggttgggt gacatagccg
    25321 taataacgcg ttggtacatt gcgcgtaaac aaggtcggct gcgtcgaaac gtaaaatccg
    25381 gcacgcgaga catacatcgc ctgttcaacc atcgacgagg tgttgtgcgc cagtcgcagc
    25441 aagtaaccaa cttccagtgc agcggtaatt tcattgtcga ggctttcatt ttcgcgagac
    25501 aggagattcc cctcgctgac taatgcatcc gatacgccat tgactgacag ggtgcgtcgt
    25561 cggttgagtt caatttgcca ggcgtgctcg tcgcgatgct gttcgaactc ggttacagca
    25621 ttacgcagtg aagtgaaatc cagtggcgct acgagagctt cgcgcatgcc attacgcaaa
    25681 aagatcagtt tgtcgacgtt atactgcaaa tgcttatcga gcgcgttggc tacgttttcc
    25741 agatgattac gctggctgga gatataggca tcttccagca ccactacttc acgccaggtg
    25801 agcaaggtgg aaaaaagcaa taccacgata aagcagagat taacgacatg accaggcccc
    25861 aggcggcgtg cgagtttttt caaccagctc tggttttcca tttttgtctc gtgctgcacc
    25921 ctgacgactc ccaacctgct tttttatgat tctggcataa cctggcgata gcgtaccgca
    25981 aaacagcgat aattttataa tggtggcatg ataagacgcg acagacatcg atagttttat
    26041 aacgtaggca tgataagacg cgatagcgtc gcatcaggca attcagtgca gacactggca
    26101 cacccgaccg gatgcgacgt gagcgccaca tccggtcggg tgttaatgat accctttcaa
    26161 acttcttccg caggacgact tccctccccc ggaacaagct cggtttcatg aaaagcttcc
    26221 cgcttgaccc cgtaaccgtc ataccaacga cactcaacca taccgctgga gtatccggtg
    26281 acaatcatcc gcgggccgcc ctctttaacc gtaacttcct cactaaccat aaagctcata
    26341 ctcgcctcct tttttcgagt gaaacttgtt caccttagtt gaagatggcg aattttgcat
    26401 aatagcctgt gcgagtatta atgtgcctga ccgcgtattt tcgctacggc tttcactccc
    26461 agcaccacga tgccgccgat gataaatcca agaatcagat ttaaaacagt cggtaatatc
    26521 atcgccacca ctgcactttg ctgcccggcg aaatgttcaa tggcgtgatg cagcggcgca
    26581 ataccatgta ccacaatccc gccgccgacg aggaacatcg ccagcgtgcc gacaatcgat
    26641 aacgctttca tcagccaggg cgcgataatc aataatcctt tacctaatgc ctgcatcagc
    26701 gcgctggatt tttccgccag ccaatacccc aggtcatcaa tcttaacgat aacccctacc
    26761 agaccgtaga cgcccacggt cactaccagc gcgatgcctg aaagcaccag cacctgatta
    26821 agcaacggcg cttcggccac aatccccagc gtgatggcga cgatttccgc agacaatata
    26881 aaatcggtac gaatcgcccc ttttattttg tccttttcaa acttcagcgg atcctgcgcc
    26941 gccagcttct ccagacgctg ctgactctgc gccggatctt ctttatgttt acgcgcctcc
    27001 agcatatgca gcactttctc taccccttca aagcagagaa acgcgccgcc aatcatcaac
    27061 agtggcgtaa tcgcccacgg gataaacgca ctgatgatca gcgccagcgg caccagaatc
    27121 actttattga tcagcgatcc tttcgccacg ccccagacca cgggaagttc ccggttggcc
    27181 cgcacgcctg aaacttgttg cgcattgagc gataagtcat cccctaatac accggcggtt
    27241 ttcttcgccg ccagtttgcc catcacggag atatcgtcca gtagagtggc gatatcatcg
    27301 agcaacgtca gtaaactact cccggccaaa agcattccct ctcattttta ttgttgaagg
    27361 gtgtaagtat gaagcaaaaa cggcagctct gatacttgct tcacaggtca acattttttt
    27421 aacaatcaag tgcaattata tctctcgcca gcagaatgat tttcacgttt actatgaacc
    27481 acctttttat ttccaccgtg agggattatg cgtttccgcc agttgttacc gctttttggc
    27541 gcgctgtttg cgttgtatat catttggggc tcaacctatt ttgtcattcg gattggcgtg
    27601 gaaagctggc ctccgttaat gatggcaggc gttcgattcc tggcagccgg tattttattg
    27661 atggcatttt tgctactgcg cggacacaaa ctccccccgc tacgtccgct gctcaatgcc
    27721 gcgctgattg gcctgttatt gctggctgtc ggtaatggca tggtgacggt tgccgaacat
    27781 caaaatgttc cttccggcat cgccgccgta gtggttgcaa ccgtgcccct ctttaccctg
    27841 tgcttcagcc gcctgtttgg cattaaaacg cgcaaactgg aatgggtggg tattgccatt
    27901 gggcttgccg gaatcatcat gctcaatagc ggtggaaatt taagcggcaa tccgtggggc
    27961 gcgattctga ttttaatcgg ctcgattagc tgggcgtttg gctcggttta tggctcgcgc
    28021 attaccttac ctgtagggat gatggcgggt gcgattgaga tgctggcggc aggcgtggtg
    28081 ttaatgatcg cgtcgatgat tgcaggtgaa aaactgacgg cactcccttc cctttcaggc
    28141 ttccttgcgg tcggctatct ggcgctgttt ggttcgatta tcgccattaa cgcttatatg
    28201 tatttaatcc gcaacgtcag tccggctctc gccaccagct acgcctacgt taacccggtg
    28261 gtcgcggtct tgctgggtac gggactgggc ggagaaacgc tgtcgaagat tgaatggctg
    28321 gcgctcggcg taattgtctt cgcggtggta ctggtcacgt tgggaaaata tctcttcccg
    28381 gcaaaccccg tagttgcgcc agttattcag gacgcatcaa gcgagtaaat gaatcccctg
    28441 cgtgtcgatc tgcgcgctgg caccttcgcc gcagatccac tcttccagac gctcgctaag
    28501 cgcttcatcc gtcagcttct cgcgcccacg taatgcacac tcccagacaa tcaatacgcg
    28561 ccagccgagt tcctgcaaac gactgatatc gcggcgatcg cgttcaacat ttttacctat
    28621 cttctccagc cagaactcgg ttcgagtcgc aggcacttta aacagatagc agtgatgatg
    28681 atgccagaag cagccgtggg taaatatcac gcagcgatat tcatcaacga caaaatccgg
    28741 gcgtccgggc agactggcgt cctgaacgcg aaatgccagg ccctgcccgg ttaacagact
    28801 ggcgaggcgc ttctctatcg ccgtatcacg cgtggcaatc gcgcgcatat ttttgctgcg
    28861 agtggcctta tcgtgaacgt cggccatgtt gtgcctcttg ctgacgcaac gccaccgcct
    28921 gtttgatttt tggctcaagc agttttgcca ccgcggcaaa gaccggcacg accaccgagt
    28981 taccgaactg gcgataggcc tgagtgtccg aaaccggaat gcggaatttc gcttctcccg
    29041 gcgcttcaaa acccattaag cgcgcgcatt cccgaggcgt taaccgacgt ggacgatgtt
    29101 gctgattcag cggatcgtca aagtctttct cacccgtggc catatcccag ccgcgatcga
    29161 ttaaaatttc cgcgccatct ttgtaataac gcgcagacag cgtacgcgtg acgctttgcg
    29221 gattgttagg atagaccatt ccataaccga agccgttacc gcgcgcctga tgttttttcg
    29281 cataacgata gaggtacttc cacagcaccg gcgtcaggat atatttcgcc tcgaccatcg
    29341 ggtccagcag ctgcgccagc gtcactcgct gtgcagggaa acattcgctg atatcacgca
    29401 gagtaaaatc ggctttcaga ttaagatcgc gacgaaaacc caccagcacg atgcgttcac
    29461 ggtgctgcgg cagaaaatgt ttaccatcga tgattttcgg atcgtccggc ccgttatctt
    29521 ctgcatcagc cacgtcatag cccagttcgt ccagcgtctg catgatgatg cggaacgttt
    29581 taccctggtc gtggcttttc aggtttttga cgttttcgag cacaaacatc gccggacgac
    29641 gcgcgtcgat aatgcgcacc acatcaaaga acagcgtgcc ctgagtatcg caggcaaaac
    29701 cgtgcgcccg cccgagcgag ttctttttcg atacgccagc cagcgaaaat ggctgacaag
    29761 ggaaaccggc cagtaaaaca tcgtgttcag gaatgtgttt acgaatatgt tccgccgccg
    29821 cctcatcact cacgccttct ttatggctga gggtgatgtc gcggatatct tcataaaaat
    29881 gatgcgtcgc cgggtcgcaa taatgattgg ctttataagt gcgtaccgca tgtttgttcc
    29941 attcgctggt aaacacgcat tgtccgccaa tcgattcaaa accgcgacgg atgccgccaa
    30001 ttccggcaaa tagatcgata aagcgaaacg cataatgcgg atgatgtgcc ggtggtttgg
    30061 gtaacaacgt ttgcagatgg gcgaactctt tctcacttaa acggtgccat gccgagtcat
    30121 tcgccagcgc acgttttaaa attgccgcgc tccagtgatt ctcacccaca ccattaagct
    30181 gcgccaccag cgttttaaca tcataaattt gcagcagttt ctccagcatt gcctgtgcgg
    30241 cattcccggt gctgtatgaa tcggttactg atatattttc ctgcatagat ttaaccggcc
    30301 atctgagatg gccgacaggt taacataatt acagccattt agggccacgc gcttatcccg
    30361 cgggtgaaaa cgcatctatc accttgtgat cgacaccttc attctccccc gccagttcgg
    30421 cactgagctt cgccataaac tcgactaaaa aatgcgcgtt gtgctgcgcc agctgcttgc
    30481 ctcttgcggt ttgcatggtt tgcggtagct tcagcaactt agtctggaaa tgatccagcg
    30541 cgtagcgttt atcatcaagc gggcgatgct gtgcgaacgg atcttcacca tcaaacagcg
    30601 ccacgcccaa tgcccctgaa acggcaaaca cgcgcgccag gccaatcgcc cccagggctt
    30661 ccagccgatc cgcatcctgg acgattttag cttccgttgt taagggggcg atttgcgcgc
    30721 tgaaactgtg agcggcaatg gcatgacaaa cggcctcgat tttctccgcc ggaaattgct
    30781 cgaactcttc acggagcagg cgacgcgtct cttctgccgc caggattgaa gaacgctgcc
    30841 tttgcggatg atttttcgcc aggctcacaa tatcgtgaaa ataacaggcg gttaaaatca
    30901 ccagcatatc gacatcgtca tctgccgcca gcttctgtgc cgtagcccag acgcggcgaa
    30961 aatgacacac gtcatgggcc gcgtcctggt gctgatgatg gtttttcaac caattttcga
    31021 actgtgcctg ccagtgttgt aagtccatac gcgctccgtt gccaaagagt cgccacctta
    31081 gcagttttta ttcatagcgt ctgctacgtg cgggacgagg tcgggtgtac caggcaatgc
    31141 tgcctaacaa tgccccgacc agagccataa ataaaaatcc gaccagtgcc cctaaccact
    31201 ttcccgcggt agagcctaaa tcgctttcaa atcccgacac gggggcatcg gggatccggc
    31261 tcatcaccca gatgtaacgc gccattgccc agacgaaata gccacaccat gtatagaaag
    31321 cccacaaagc cagtttgccg ccagggctgc gagagagtct ctcttccatc tttgtcgaac
    31381 cgtattccat tttgagataa cccggaaaat tcagacttag tactattatg tgataaaagt
    31441 cacatttttc cacattggat gagccagtca agactcactc attttttgaa caaatagata
    31501 atttttgcgc aacggcagtg aatacaggaa aaatcgtttt gagcgatttt atttatcttt
    31561 gatatcggct ttattaattc
//
LOCUS       DAPHKZ010000046        31315 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.046, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000046 DAPHKZ010000000
VERSION     DAPHKZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.046"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(246..464)
                     /gene="infA"
                     /locus_tag="RH288_002222"
     CDS             complement(246..464)
                     /gene="infA"
                     /locus_tag="RH288_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDV4031270.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(749..1453)
                     /gene="aat"
                     /locus_tag="RH288_002223"
     CDS             complement(749..1453)
                     /gene="aat"
                     /locus_tag="RH288_002223"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HDV4031271.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQR
                     GIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGC
                     ASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFS
                     RMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGR
                     LPNNFWVPRCLFSPQE"
     gene            complement(1495..3216)
                     /gene="cydC"
                     /locus_tag="RH288_002224"
     CDS             complement(1495..3216)
                     /gene="cydC"
                     /locus_tag="RH288_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HDV4031272.1"
                     /translation="MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLS
                     ASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDF
                     TLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGA
                     SDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRISDLTDQKPEVTFPDTQTRVA
                     DRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEIL
                     RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDAT
                     TESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRY
                     YQFKQGL"
     gene            complement(3217..4983)
                     /gene="cydD"
                     /locus_tag="RH288_002225"
     CDS             complement(3217..4983)
                     /gene="cydD"
                     /locus_tag="RH288_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HDV4031273.1"
                     /translation="MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWF
                     MARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFP
                     SNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGEL
                     DFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAH
                     PQRGEAELASTDPVTIEAEELFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSL
                     LNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
                     SEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLL
                     LDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGR
                     YAELSVAGGPFATLLAHRQEEI"
     gene            complement(5106..6071)
                     /gene="trxB"
                     /locus_tag="RH288_002226"
     CDS             complement(5106..6071)
                     /gene="trxB"
                     /locus_tag="RH288_002226"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDV4031274.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNG
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK"
     gene            6616..7110
                     /gene="lrp"
                     /locus_tag="RH288_002227"
     CDS             6616..7110
                     /gene="lrp"
                     /locus_tag="RH288_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HDV4031275.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            7245..11234
                     /gene="ftsK"
                     /locus_tag="RH288_002228"
     CDS             7245..11234
                     /gene="ftsK"
                     /locus_tag="RH288_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDV4031276.1"
                     /translation="MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     SDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYE
                     DDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDE
                     EITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWA
                     APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQ
                     YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQ
                     TEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARERE
                     QLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAA
                     TVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKA
                     REAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAA
                     EAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQ
                     QPQQPVAPQQQYQQPQQPVPPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPV
                     APQQQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPV
                     DTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLA
                     RSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDI
                     AGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELS
                     VYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRM
                     MRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKAR
                     AAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDM
                     LYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGA
                     EELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNR
                     EVLAPPPFD"
     gene            11393..12004
                     /gene="lolA"
                     /locus_tag="RH288_002229"
     CDS             11393..12004
                     /gene="lolA"
                     /locus_tag="RH288_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HDV4031277.1"
                     /translation="MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK"
     gene            12015..13358
                     /gene="rarA"
                     /locus_tag="RH288_002230"
                     /gene_synonym="mgsA"
     CDS             12015..13358
                     /gene="rarA"
                     /locus_tag="RH288_002230"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HDV4031278.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEANAYAAGEVYFPPEIAQTHYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR"
     gene            13449..14741
                     /gene="serS"
                     /locus_tag="RH288_002231"
     CDS             13449..14741
                     /gene="serS"
                     /locus_tag="RH288_002231"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDV4031279.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF
                     HTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            14980..17424
                     /gene="dmsA"
                     /locus_tag="RH288_002232"
     CDS             14980..17424
                     /gene="dmsA"
                     /locus_tag="RH288_002232"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415414.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HDV4031280.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAH
                     AVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGEGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCEL
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDP
                     QGHHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGF
                     ESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGIHNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDAKRVDKGGCINVLTTQRPSPL
                     AKGNPSHTNLVQVEKV"
     gene            17435..18052
                     /gene="dmsB"
                     /locus_tag="RH288_002233"
     CDS             17435..18052
                     /gene="dmsB"
                     /locus_tag="RH288_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HDV4031281.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            18054..18917
                     /gene="dmsC"
                     /locus_tag="RH288_002234"
     CDS             18054..18917
                     /gene="dmsC"
                     /locus_tag="RH288_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     DmsC"
                     /protein_id="HDV4031282.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRV
                     IACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGW
                     LLAMLKKLSPALRTLWLIVTMVLGVIFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
                     MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVVSVMQGAELATIHSSVQQAAA
                     LVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYG
                     LHMTVGMAVAS"
     gene            complement(18952..19578)
                     /locus_tag="RH288_002235"
     CDS             complement(18952..19578)
                     /locus_tag="RH288_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDV4031283.1"
                     /translation="MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALG
                     DLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDTPYIARPGNINAWDNEDFVKAVKA
                     TGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRLSQAGA
                     QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK"
     gene            19892..21040
                     /locus_tag="RH288_002236"
     CDS             19892..21040
                     /locus_tag="RH288_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4031284.1"
                     /translation="MSTYTQPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVG
                     VVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRF
                     VAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
                     LPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITSMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV"
     gene            21250..22680
                     /locus_tag="RH288_002237"
     CDS             21250..22680
                     /locus_tag="RH288_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415419.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV4031285.1"
                     /translation="MAGNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSW
                     VFIFALYFTPYALIVGQLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLA
                     QKPQAILIALGWAMKGDGSLIKEYSVVALQGLTLVLFIFFMWVASRGMKSLKIVGSVA
                     GIAMFVMSLLYVAMAVTAPAITEVHIATTNITWETFIPHIDFTYITTISMLVFAVGGA
                     EKISPYVNQTRNPGKEFPKGMLCLAVMVAVCAILGSLAMGMMFDSRNIPDDLMTNGQY
                     YAFQKLGEYYNMGNTLMVIYAIANTLGQVAALVFSIDAPLKVLLGDADSKYIPASLCR
                     TNASGTPVNGYFLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAF
                     IAVVRLAQKYKPEYVFIRNKPLAMTVGIWCFAFTAFACLTGIFPKMEAFTAEWTFQLA
                     LNVATPFVLVGLGLIFPLLARKANSK"
     gene            complement(22681..23589)
                     /locus_tag="RH288_002238"
     CDS             complement(22681..23589)
                     /locus_tag="RH288_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4031286.1"
                     /translation="MRMNMSDFATFFAVARNQSFRAAGDELGLSSSAISHSIKTLEQR
                     LKIRLFNRTTRSVSLTEAGSNLYERLRPAFDEIQIMLDEMNDFRLTPTGTLKINAARV
                     AARIFLMSLLVGFTREYPDIKVELTTDDSLVDIVQQGFDAGVRLSCIVEKDMISVAIG
                     PPVKLCVAATPEYFARYGKPRHPHDLLNHQCVVFRYPSGKPFHWQFAKELEIAVAGNI
                     ILDDVDAELEAVLMGAGIGYLLYEQIKEYLDTGRLECVLEDWSTERPGFQIYYPNRQY
                     MSCGLRAFLDYVKTGQICQSQRHRPQ"
     gene            23689..24279
                     /locus_tag="RH288_002239"
     CDS             23689..24279
                     /locus_tag="RH288_002239"
                     /EC_number="1.6.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H oxidoreductase"
                     /protein_id="HDV4031287.1"
                     /translation="MQSERIYLVWAHPRHDSLTAHIADAIHQRAMERKIQVTELDLYR
                     RNFNPVMTPEDEPDWKNMDKRYSPEVHQLYSELLEHDTLVVVFPLWWYSFPAMLKGYI
                     DRVWNNGLAYGDGHKLPFNKVRWVALVGGDKESFVQMGWEKNISDYLKNMCSYLGIED
                     ADVTFLCNTVVFDGEELHASYYQSLLSQVRDMVDAL"
     gene            complement(24361..25158)
                     /gene="pflA"
                     /locus_tag="RH288_002240"
     CDS             complement(24361..25158)
                     /gene="pflA"
                     /locus_tag="RH288_002240"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015696619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HDV4031288.1"
                     /translation="MSNLTNCNTTENTATAGATKSVIGRIHSFESCGTVDGPGIRFIT
                     FFQGCLMRCLYCHNRDTWDTHGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAIL
                     QAEFVRDWFRACKKEGIHTCLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQN
                     LVGVSNHRTLEFAKYLANKNVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIEL
                     LPYHELGKHKWVAMGEEYKLDGVKPPKKETMERVKGILEQYGHKVMF"
     gene            complement(25190..26185)
                     /locus_tag="RH288_002241"
     CDS             complement(25190..26185)
                     /locus_tag="RH288_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016158965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV4031289.1"
                     /translation="MSIKKLDDGRYEVDVRPQGADGKRIRRKFKTKGEAQAFERHVLV
                     NYHNKEWLEKPADRRTLTELLGRWWIYHGKSHERGDIERGRLTTIIAKFAEMGVSRAD
                     QLTKKTITDYRVVMMNDGLKPASVNRHLAIMSGMFTKLIDAGEYHSHNPFREIKRLRE
                     AVTEMAFLSSEEITRLLSMLDGDELNATLVCLSTGGRWSEVSNLKAEHIINQMVTFMK
                     TKNGKRRTIPVSQDLIKRIKTKNSGRLFNASYYKVRNALREVKPDLPDGQAVHVLRHT
                     FATHFIMNGGNIITLQRILGHSNIQQTMTYAHFAPDFLQDAVTLNPVSGMSIMRP"
     gene            complement(26279..26578)
                     /locus_tag="RH288_002242"
     CDS             complement(26279..26578)
                     /locus_tag="RH288_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV4031290.1"
                     /translation="MSSEQSEKLKLIRESERLKTKELAELIGINYYTYHGYESGKSKM
                     PMEAGMKLFKHPRFRKYRDWFMFDETDPAAGQIAPALAHIGQDSTTLHHSDQKTG"
     gene            26687..27043
                     /locus_tag="RH288_002243"
     CDS             26687..27043
                     /locus_tag="RH288_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001442926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031291.1"
                     /translation="MTTNVEISCPTSDEASFENEAKRKSIQISERPSDLLSKEGFALY
                     IGKTPRAVAEMAKAGKLPAFYMTDPLKPRGKAELWINRREWDKYAAQLVDEAPTEWHD
                     WKNRISYSKSRHGRAA"
     gene            27221..27721
                     /locus_tag="RH288_002244"
     CDS             27221..27721
                     /locus_tag="RH288_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein B"
                     /protein_id="HDV4031292.1"
                     /translation="MTVMTLNLVEKQPAAMRRIIGKHLAVPRWQDTCDYYNQMMERER
                     LTVCFHAQLKQRHATMRFEEMNDVERERLVCAIDELRGAFSKRRQVGASEYAYISFLT
                     VSQRRTLFMHAGLTEKEFNQPYWRINEESCYWRDALFRALRELFSLFEYAPTILTSVK
                     PEQYLH"
     gene            27785..28009
                     /locus_tag="RH288_002245"
     CDS             27785..28009
                     /locus_tag="RH288_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 family protein"
                     /protein_id="HDV4031293.1"
                     /translation="MHTVSENQCGKYTLLLQQARTEAQADAATRFSSHLDAMIRHITK
                     AELSRVEIVELLSQESEKFHNIGLSRGEVL"
     gene            28009..28308
                     /locus_tag="RH288_002246"
     CDS             28009..28308
                     /locus_tag="RH288_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5405 family protein"
                     /protein_id="HDV4031294.1"
                     /translation="MSCSHSVVLLNNALKIAVMKNGDLSLIQLCLDKEKRDITESVIA
                     IYQNELNLLSDVVNLLVKRAVFHKQISSVDELTKLTTELASYCADVSRKLNDKRS"
     gene            28311..28535
                     /locus_tag="RH288_002247"
     CDS             28311..28535
                     /locus_tag="RH288_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HDV4031295.1"
                     /translation="MPDNVDFIQEQQAELLERQINAARVKHCGASALVCEECDAPIPA
                     ARRAAYPSATRCVSCQSVFEAKNKHYRRMA"
     gene            28532..28807
                     /locus_tag="RH288_002248"
     CDS             28532..28807
                     /locus_tag="RH288_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5405 family protein"
                     /protein_id="HDV4031296.1"
                     /translation="MSIRIEIGERYVVTSDSFQFILHEKKRAESGKNAGQEWLAVVGY
                     YPKLSQLVSGLMHHDILTGSAKSFADLNAQVEQLSRRCSEAFGSYGR"
     gene            28797..31082
                     /locus_tag="RH288_002249"
     CDS             28797..31082
                     /locus_tag="RH288_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001726608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HDV4031297.1"
                     /translation="MAVKASGRFVPPSAFAAGTGKAFTGAYAWNAPREAVGRERPLTR
                     DEMRQVQGVLSTINRLPYFLRSLFTSRYDYIRRNKSPVHGFYFLTSTFQRRLWPRIER
                     VNQRHEMNTDASLLFLAERDHYARLPGMNDKELKKFAARISSQLFMMYEELCDAWVDA
                     HGEKESLFTDEAQAHLYGHVAGAARAFNISPLYWKKYRKGQMTTRQAYSAIARLFNDE
                     WWISQLKGQRMRWHEALLIAVGEVNKDRSPYASKHAIRDVRARRQANLEFLKSCDLEN
                     RETGERIDLISKVMGSISNPEIRRMELMNTIAGIERYAAAEGDVGMFITLTAPSKYHP
                     TRQVRKGESKTVQLNHGWNDEAFNPKDAQRYLCRIWSLMRTAFKDNDLQVYGLRVVEP
                     HHDGTPHWHMMLFCNPRQRNQIIEIMRRYALKEDGDERGAARNRFQAKHLNRGGAAGY
                     IAKYISKNIDGYALDGQLDNDTGRPLKDTAAAVTAWASTWRIPQFKTVGLPTMGAYRE
                     LRKLPRGVSIADEFDERVEAARAAADSGDFALYISAQGGANVPRDCQTVRVARSPSDE
                     VNEYEEEVERVVGIYAPHLGARHIHITRTTDWRIVPKVPVVEPLTLKSGIAAPRSPVN
                     NCGKLTCGDTSLPAPTPSEHAAAVLNLVDDGVIEWNDPEVVRALRGAFKHGLRTPNRQ
                     QRNGSPLKQYEMAPSARLTRSERMQITRIRVDLAQNGIRPQRWELEALARGATVNYDG
                     KKFTYLVDEEWLEDITDIKWI"
BASE COUNT         7815 a         7583 c         8132 g         7785 t
ORIGIN      
        1 ttgctaccaa acctcatggg tggcaacggg gcgctactat agggagttgg agtaaaacgg
       61 tcaagaagaa ttttaatgat aattattgtt tgctcatact gtaaacaagt tgtgcagtat
      121 atctacatcg agacaagtta cggacttata cttccaaagt acttcataca tatcacaaaa
      181 taaaaaggcc ggttaaaccg accttttact cgttctttct cttcgcccat caggcggtaa
      241 aacaatcagc gactacggaa gacaatgcgg cctttgctca ggtcgtacgg ggtcagttca
      301 acagtcactt tgtcgcccgt caggatgcgg atgtagtttt tgcgcatttt accggagatg
      361 tgtgcagtaa ccacgtgacc gttttctaac tctacgcgga acatggtatt aggcaacgtt
      421 tcaagaacgg taccttgcat ttcaatattg tcttctttgg ccatctaatc ctctggggta
      481 tcactaccgt aatttgaacc ggcaagataa tgccgaagtt ctgtaaataa gtaaagattt
      541 gcgcgctaaa tcgcaacaaa caggttcggc acattactcc gaaaacacac ggctaagccg
      601 caccaaaagc gcaacgtata agggagcggt gagataaacg atgggcgtta cctgacgcga
      661 aaaattcctt atcggcagcg gggtaatgag cgtaaccaac tctgcgaccg caattataac
      721 actctgggga gaaatgtgcc gaaaacattc attcttgtgg tgaaaacaag catcgtggta
      781 cccagaaatt attcggcaat cgtccgaggc gcatttgatt gagataatta aggtaatccc
      841 ggcggggaat ttcgcaggca ccaagcgatg ctgtgtgatc gttaaggacc tggcagtcga
      901 taagcttacc gccatgaccg ataaattcct cacagaatac cagaagcgcc gttttagacg
      961 cattttccat ccggctgaac atggactcgc cacaaaatag cgttccctgg gccacgccgt
     1021 acataccgcc gacaagctca tcttcacgcc agacttcaat ggagtgggca tggccgagtt
     1081 cgtgaaggcg atggtaggct tcgaccacgc cacgcgtgat ccaggttcct tcttcgcgat
     1141 cgctggcaca gccttcaatg acctgaccaa aagcgtaatt catcgtgaca cgatagggcg
     1201 agcgtttatg aaatcgcttc atactacggc tgatatgcag tgattctggc catagcaccg
     1261 cgcggggatc gggcgaccac cagaggatgg ggtcgcctgg agaaaaccac ggaaaaatac
     1321 cacgctggta agccattaac aggcgcgcag ggctaagatc gcccccaagt gccagcaggc
     1381 cgttaggctc acgtaatgcg ccttccgggg aagggaaggc tattgaatgg cgagaaagct
     1441 gaaccaggcg catgaccgca aaactccacg caagtcggat cgttcaataa tagcttacaa
     1501 accctgcttg aactggtaat aacgcccctg tctggcaagc agttctgcgt gagtaccttg
     1561 ctcaataatt tgcccgttgt ccatcactat tatttgttgg aaacgagaga gtccgcgaag
     1621 tcgatgggtg accattaaca ccgttttctc acgcatcatt tctgcaagca attcaaggat
     1681 ctggctttcg gttgtggcat ctaagccttc ggtaggttca tccagcaaca ccagtggcgc
     1741 atcatgtaac agcgcacggg cgatagccag acggcgcagt tcaccaccgg agagctggcg
     1801 tccgccttca cctaaccaac tgttgagacc tgcatcctcg agcagctttt ccaggccaac
     1861 gcgacgcaag atctccgaca gagcctcatc actactgcca ggcgaggcga gtaaaagatt
     1921 atcacgcagc gtggcgctaa acagatgcac tcgctgagga acaacgctga tggtctgtcg
     1981 tagagccgct tcattcaggc tggctatggg gctatcgtta agcaaaatct cgccctgttg
     2041 cgggtcccat gcgcgggtca gcagttgtaa cagtgttgat ttgccgcatc cggttcgccc
     2101 gagaatcgct atatgttccc cggcgtttac ctgaagagaa atccctttaa gtgcctgttg
     2161 agattgctcc ggataagtga actgaacatc ccgtaacgtc agcgaaacgc gatcggcaac
     2221 acgagtttgg gtatcaggaa aggtgacctc cggtttttga tccgttaagt cagagatacg
     2281 tacggcagag gcaatgactt gccccagatg ctgaaatgca cccgttactg gtgccagtgc
     2341 ttcaaacgcg gctaacgcgc agaagacaaa cagggcaatt aacgcgccgg gttgagcatt
     2401 gccgccaacg ccgccagacg ccatccacag catcaggatc accgctaacg cgccaatgag
     2461 cagcattatc gcttgcgaca atgcggtcag ttcagattga cggcgttgcg cttccagcca
     2521 ttgaatttct gtattctcta gttgcgtgcg ataacgatcg ctggcaccaa aaatggtcag
     2581 ctcagcttgc ccttgcagcc aggccgtcag ttgttggcga tactgtccgc gaagatgagt
     2641 cagattttgc ccggtgcttt ttcccgcacg ataaaacagc ggtggcatca ggaaaagcgt
     2701 cagtaacata atgccgccca gcgtaaaggc gagggtgaaa tcaaggaaac ttaacccgat
     2761 tgtcaccacc ataatcacca caaaagcgcc caccagcggc gagataacgc gcaggtaaag
     2821 atgatcgagc gtatcaacat ccgccaccac gcgattgagc aattcgccct gacgatagcg
     2881 cgccagtccg gcaggggaga ggggcagcaa tttgctgaag gtgtaaatgc gcagatgctg
     2941 caacacgcgg aaagtcgcgt cgtgacttac cagacgttca aaatagcgcc cggcagtacg
     3001 ggtgattgct gcgccacgca cgcccgcagc gggtagcata tagttgaagc tgtacagtcc
     3061 ggcaaccccc gcaaccgctg aggccgagag gaaccagccg gaaagtgtca acagaccgat
     3121 actggcgagc agcgtcacaa ttgccagcac aataccaaga cttaacatcc atttatgacg
     3181 tttatacagt gccagatagg gtagcaaagc gcgcatttaa atctcctcct gacgatgggc
     3241 cagtaatgtg gcgaatgggc caccagccac acttaattcc gcgtaacgtc cttgctcaat
     3301 aatccggcca tcctgcataa cccaaatgac atcccagtca gcaagatctt ctaactggtg
     3361 ggtgaccatt aacgttgttt ggcgcagaga ggcggcattc agcgcctcca ttacgcgctg
     3421 ttcactgtga gcatcaaggc tggcagcggg ttcatccaac agtaatagcg aacagggatt
     3481 tagtaacgca cgggccaccg ccacgcgctg cgcctgcccc acggaaaggc gggcagcctg
     3541 gtcgccaaca ggcgtatcaa cgccttgtgg gaggagcggt agaaactcgc tgacccaggc
     3601 gttatccagc gctgcttgta attcttgttc gctggcatca ggtcgcgcca gtagtacgtt
     3661 atcccgcaat gttgctgccg gtaattgtgg gttttgccca acccaggaga gatgtttacg
     3721 ccatgattct ggtgataaat cgcgtaattc tatcccgttg attcgtagcg atccctgata
     3781 tgagagaaaa ccagaaagcg cgttcagcag tgagctttta cctgaaccgc tgcgaccaac
     3841 caacaccgca cgttggcctg ctggcaaagt aaagttcagc ggtccggcca gcgttttacc
     3901 ttccggcgac gtgataaaca gctcctcggc ctcaatggtc accggatcgg tcgatgctaa
     3961 ttccgcctca ccacgttgcg gatgggcgag cggggtttcc ataaacgttt tcagactgtc
     4021 agctgcgcca acagcctggg ctttagcatg ataaaacgta ccgagatcgc gtaatggctg
     4081 gaaaaactct ggcgcaagga tcagggccag aaaacccgca gccagcgtca caccggtatc
     4141 gtagtgacca aaatccagct cgccgagata ggaaaaacca aagtagaccg ccaccagagc
     4201 aattgacagc gaggtaaaaa attcgagaat gccggaggat aaaaacgcca gccgtagcac
     4261 ttccattgtc cgttggcgga aatcttccga agcagaacga atactttcaa tttcagcttc
     4321 accacgacca aaaatacgca atgtttccat gccgcgcagg cgatcgagga aatgcccact
     4381 taagcgagca agagcgagaa agttacgtcg gttagcatcg gcagccccca ttccaaccag
     4441 cgccataaac aacggaatta acggtgcagt gcccagcaga atgagcgccg cagcccagtt
     4501 agaggggaag attgccacca caatcagcaa cggcaccgac actgccagcg ccatttgcgg
     4561 cagatagcgt gcatagtaat catgcatatc gtcaatttgc tcgagtacca gcgtcgccca
     4621 gctccccgca ggtttaccct gaatccacgc tggccctgct tgttgcagac ggtcgagaac
     4681 ctgacggcgg atggcaaagc ggatatgctg cccggcgtga taacccaccc gttcgcgtaa
     4741 ccagaccacc catgcgcgca gtacaaaggt cagaaccagt aacgtaaagg gaagcagcag
     4801 ggcttcacgg ggaatattct ccataatcat atgttgcaga attcgcgcca tgaaccaggc
     4861 ctgggcaatg atcaatatgc cgctcacaaa gcccagcaga cgagaaatat tcagccaacg
     4921 ttgggagatg acgctttgct gttttaacca gcgggttaac tctttttgac gagatttatt
     4981 cattgcacgc ttagcaggtg agttatcaga attatttgca gagcaatgtt acaacgggga
     5041 aaaaataaag gcgacccata gtcgcatggt gtcgccttct ttacttttgt tactgatttg
     5101 taaaattatt ttgcgtcagc taaaccatcg aggtagcgtt ccgcatcaag tgctgccatg
     5161 cagcctgtac cggccgaagt aatggcctgg cgataaatgt gatccatcac gtcgcctgcg
     5221 gcaaagacgc caggaatgct ggtctgggtg gcattaccat gaatacccga ctgtactttg
     5281 atgtagccgt tttccagttc cagctgccct tcgaaaatcg cagtattcgg gctgtgaccg
     5341 atagcaacaa acagaccggc aacgtcgagt gactcgatgt tatcgctgtt ttgcgtatcg
     5401 cgcagacgaa cgccagtgac acccatttga tcgccggtca cttcttccag cgtacggttg
     5461 gtgtgcagaa tgatgttgcc gttctccact ttatccatca ggcgcttaat gaggattttt
     5521 tccgcgcgga aaccgtcacg gcggtgaatc agatgcactt ccgaagcgat gttagacaga
     5581 tacagcgcct cttcaaccgc ggtattgccg ccgccgatga ccgcaacttt ctggttgcga
     5641 tagaagaaac cgtcgcaggt tgcacaagca gaaaccccac ggcctttaaa ggcttcttca
     5701 gagggcaggc cgagatagcg tgcagaagct ccggtggcaa taatcagcgc gtcgcaagtg
     5761 tattcgccgt tatcgccatt cagacggaac ggacggtttt gcagatccac cttgttgata
     5821 tgatcaaaaa tgatctcagt ttcaaacttg gtggcatgtt cgtgcatgcg ctccattaat
     5881 aacggaccgg tcagatcgtt tggatcgcca ggccagtttt ccacttccgt ggtggtggtc
     5941 agttggccgc ctttttccat gccggtaatc agcacaggtt gcaggttggc gcgcgccgcg
     6001 tagacagcag cggtgtatcc cgccgggcct gaacccagga taagcagttt actgtgtttg
     6061 gtcgtgccca tgagatcccc atagttgttg gcagacaatg ggcaggattg tagggaattt
     6121 acagacgtaa aaaaagagta tgacgatttt gttaacaatt tgtgcaatcg gcagcatcga
     6181 taagcaggtc aaattctccc gtcattatca cctctgctac ttaaatttcc cgctttataa
     6241 gccgattaaa tgatgaataa acgcccctgt taatgaatat ctggcatgtt gtactaaaaa
     6301 tcgatgtttt gctttgacaa tcccctggtg ttttgcgaaa acattcgagg aagaaaaaaa
     6361 acagtattct tatatgcgca taaccatgca tgtaaatacc atgtttaccg tgctagtgaa
     6421 atctacgtat ggcgtggaca gacgccattc gtgatgtcga tagctgccac aaggcaacgg
     6481 tcttctcacc gtagacccag gcattgcgcg ccgtgaatct tcatgatttc ggtctatcgt
     6541 gacgggtagc gactctgaac agtgatgttt cagggtcaga caggagtagg gaaggaatac
     6601 agagagacaa taataatggt agatagcaag aagcgccctg gcaaagatct cgaccgtatc
     6661 gatcgtaaca ttcttaatga gttgcaaaag gatgggcgta tttctaacgt cgagctttct
     6721 aaacgtgtgg gactttcccc aacgccgtgc cttgagcgtg tgcgtcggct ggaaagacaa
     6781 gggtttattc agggctatac ggcgctgctt aacccccatt atctggatgc atcacttctg
     6841 gtattcgttg agattactct gaatcgtggc gcaccggatg tgtttgaaca attcaatacc
     6901 gctgtacaaa aacttgaaga aattcaggag tgtcatttag tatccggtga tttcgactac
     6961 ctgttgaaaa cacgcgtgcc ggatatgtca gcctaccgta agttgctggg ggaaaccctg
     7021 ctgcgtctgc ctggcgtcaa tgacacacgg acatacgttg ttatggaaga agtcaagcag
     7081 agtaatcgtc tggttattaa gacgcgctaa cacggaacag gtgcaaaatc ggcgtatttt
     7141 gattacactc ctgttaatcc atacagcaac agtactgggg taacctggta ctgttgtccg
     7201 ttttagcatc gggcaggaaa agcctgtaac ctggagagcc tttcttgagc caggaataca
     7261 ctgaagacaa agaagtcaca ttgacaaagt taagtagcgg ccgccgcctt ctggaggcgt
     7321 tgctgatcct tattgtcctg tttgccgtct ggttgatggc tgccttacta agctttaacc
     7381 cttcggaccc cagctggtcg caaacggcct ggcatgaacc tatccataat ttaggtggga
     7441 tgcccggtgc gtggttggca gatacgctgt tctttatttt tggcgtgatg gcttacacca
     7501 ttcccgtcat tattgtcggc ggttgttggt ttgcctggcg tcatcagtcc agcgacgaat
     7561 acattgatta ttttgccgtt tcgctacgca tcattggcgt tttggcgctc atccttacct
     7621 cctgtggtct ggcggcaatc aacgctgacg atatctggta ttttgcctcc ggtggcgtca
     7681 ttggcagctt actaagcact acgctacaac cactgctaca cagtagcggg ggaactattg
     7741 cgctgctctg cgtttgggca gcgggcctga cgttgttcac cggttggtca tgggtgacca
     7801 ttgctgaaaa actcggcggc tggattttaa acattctcac cttcgccagt aatcgtaccc
     7861 gtcgcgatga tacctgggtc gatgaagatg agtatgaaga cgacgaagag tatgaagatg
     7921 aaaatcacgg caaacagcat gaatcacgcc gtgcccgtat tcttcgcggc gcgctagcgc
     7981 gtcgtaaacg gttggcggaa aaattcatta atccgatggg gcggcaaaca gacgctgcgt
     8041 tgttctccgg taagcggatg gatgatgacg aagagattac ctacactgca cgcggtgtgg
     8101 ctgccgaccc ggacgacgtc ctattttcgg gcaatcgtgc aacgcagcca gaatatgacg
     8161 aatacgatcc attattaaac ggtgcgccaa ttaccgaacc tgtcgctgta gcagctgctg
     8221 ctaccacggc gacacaaagc tgggctgcgc cggttgaacc tgtgactcag acgccgcctg
     8281 ttgcctctgt tgatgttcca cctgcgcaac ctacagtagc ctggcagcct gtaccgggtc
     8341 cacaaacggg agagccggtt attgctcctg caccggaagg ttacccacag cagtcacaat
     8401 atgcgcagcc tgcagtgcaa tataatgagc cgctgcaaca accagtacag ccgcagcagc
     8461 cgtattatgc acctgcagct gaacaacctg cgcaacagcc gtattatgcc cctgcgccag
     8521 aacaaccggt ggcaggtaac gcctggcaag ccgaagagca gcaatccact tttgctccac
     8581 agtctacata ccagactgag caaacttatc agcagccagc cgctcaggag ccgttgtacc
     8641 aacagccgca acccgttgaa cagcagcctg ttgtggagcc tgaacccgtt gtagaagaga
     8701 caaaacccgc gcgtccgccg ctttactact ttgaagaagt tgaagagaag cgagcccgtg
     8761 aacgtgaaca acttgcggcc tggtatcaac cgattccaga accggttaaa gaaccagaac
     8821 cgatcaaatc ttcgctgaaa gcaccttctg ttgcagcagt acctccagta gaagccgctg
     8881 ccgctgtttc cccgctggca tctggcgtga aaaaagcgac actggcgacg ggggctgccg
     8941 caaccgttgc cgcgccagtc ttcagtctgg caaatagcgg tggaccgcgt cctcaggtca
     9001 aagaggggat tggtccgcag ttgccacgac cgaaacgtat ccgcgtgcca actcgtcgtg
     9061 aactggcgtc ttacggtatt aagctgccct cacagcgtgc ggcggaagaa aaagcccgtg
     9121 aagcccagcg caatcagtac gattctggag atcagtacaa cgatgatgaa atcgatgcga
     9181 tgcagcagga tgaactggca cgtcagttcg cccagacaca gcagcaacgc tatggcgaac
     9241 agtatcaaca tgatgtgccc gtaaacgcag aagatgcaga tgctgcggca gaggctgaac
     9301 tggctcgtca gtttgcgcaa actcaacaac aacgttattc cggcgaacaa ccggctgggg
     9361 cgaatccgtt ctcgctggat gattttgaat tttcgccaat gaaagcgttg ctggatgatg
     9421 gtccacacga accgttgttt acgccaattg ttgaacctgt acagcagccg caacaaccgg
     9481 ttgcaccgca gcagcaatat cagcagccgc aacaaccagt tccgccgcag ccgcagtatc
     9541 agcagccaca acagccggtt gcgccgcagc cacaatatca gcagccgcaa caaccggttg
     9601 cgccacagca gcaatatcag cagccgcaac aaccggttgc gccgcagcag cagtatcagc
     9661 agccacaaca gccagttgcg ccacaaccgc aggataccct gcttcatccg ctgttgatgc
     9721 gtaatggcga cagccgtccg ttgcataaac cgacgacgcc gctgccttct ctggatttgc
     9781 tgacaccgcc gccgagcgaa gtggagccgg tagatacctt tgcgcttgaa caaatggctc
     9841 gcctggtgga agcgcgtctg gctgatttcc gtattaaagc cgatgtcgtc aattactctc
     9901 cggggccggt tatcactcgc tttgaattga acctggcacc gggcgtaaaa gcggcgcgca
     9961 tttctaactt gtcacgggac cttgcccgtt cactttcgac ggtggcggtg cgtgtcgttg
    10021 aagttattcc tggcaaaccc tatgtaggtc tggagttacc gaataaaaaa cgacaaaccg
    10081 tttatctgcg cgaagttttg gataacgcca aattccgcga taatccgtcg ccattaaccg
    10141 tggtgctggg taaagatatc gccggtgagc cggtggttgc cgatctggcg aaaatgccgc
    10201 acttgttggt tgcggggact accggttccg gtaaatctgt cggtgtgaac gcgatgatcc
    10261 tgagcatgct ttataaagca cagccagaag atgtgcgttt catcatgatc gacccgaaaa
    10321 tgctggagct ttcggtttat gaaggcattc cgcatctgtt aacggaagtc gttactgata
    10381 tgaaagatgc cgccaacgcg ctgcgctggt gtgttaacga gatggagcgt cggtataaac
    10441 tgatgtctgc gctgggtgtg cgtaatctgg cgggttataa cgaaaaaatt gctgaagccg
    10501 atcgcatgat gcgtccgatt ccagacccgt actggaagcc gggtgacagt atggatgccc
    10561 agcatccggt gctgaaaaaa gaaccataca ttgtggtgtt ggttgacgaa tttgccgacc
    10621 tgatgatgac ggtaggtaaa aaagtggaag agctgatagc acgtctggcg caaaaagccc
    10681 gtgccgcggg tatccacctc gtactggcaa ctcagcgtcc atcggttgat gttattactg
    10741 gtctgattaa agcgaatatt ccgacccgta tcgcctttac cgtatccagt aagattgact
    10801 cacgtaccat tcttgatcag gctggcgcgg aatcactgct gggtatgggg gatatgctct
    10861 actctgggcc gaactccacg ttgccggtac gtgtccatgg tgcttttgtt cgcgatcagg
    10921 aagttcatgc cgtggtgcag gactggaaag cgcgtggtcg cccacagtat gttgatggca
    10981 tcacctccga cagcgaaagc gaaggtggtg cgggtggttt cgatggcgct gaagaactgg
    11041 atccgttgtt cgatcaggcg gtgcagtttg tcactgaaaa acgcaaagcg tcaatttctg
    11101 gcgtacagcg tcagttccgc attggttata accgtgcagc gcgtattatc gaacagatgg
    11161 aagcgcaggg gattgtcagc gaacaggggc acaacggtaa tcgtgaagtg ctggccccac
    11221 cgccgtttga ctaactaatg catcgtatgc cggataaggc gcggtagcgt cgcatccggc
    11281 actctatcaa ctgaaaattc agtattttct tctttcctca agctgattat tagcctggaa
    11341 tagagagtag agggaactcc cgatcgggag tgacgtaatt tgaggaataa tgatgaaaaa
    11401 aattgccatc acctgtgcat tactctcaag cttagtagca agcagcgttt gggctgatgc
    11461 cgcaagcgat ctgaaaagcc gcctggataa agtcagcagc ttccacgcca gcttcacaca
    11521 aaaagtgact gacggtagcg gcgcggcggt gcaggaaggt cagggcgatc tgtgggtgaa
    11581 acgtccaaac ttattcaact ggcatatgac acaacctgat gaaagcattc tggtttctga
    11641 cggtaaaaca ctgtggttct ataacccgtt cgttgagcaa gctacggcaa cctggctgaa
    11701 agatgccacc ggtaatacgc cgtttatgct gattgcccgc aaccagtcca gcgactggca
    11761 gcagtacaat atcaaacaga atggcgatga ctttgtcctg acgccgaaag ccagcaatgg
    11821 caatctgaag cagttcacca ttaacgtggg acgtgatggc acaatccatc agtttagcgc
    11881 ggtggagcag gacgatcagc gcagcagtta tcaactgaaa tcccagcaaa atggggctgt
    11941 ggatgcagcg aaatttacct tcaccccgcc gcaaggcgtc acggtagatg atcaacgtaa
    12001 gtagaggcac ctgagtgagc aatctgtcgc tcgatttttc ggataatact tttcaacctc
    12061 tggccgcgcg tatgcggcca gaaaatttag cacagtatat cggccagcaa catttgctgg
    12121 ctgcggggaa gccgttgccg cgcgctatcg aagccgggca tttacattct atgatcctct
    12181 gggggccgcc gggtaccggc aaaacaactc tcgctgaagt gattgcccgc tatgcgaacg
    12241 ctgatgtgga acgtatttct gccgtcacct ctggcgtgaa agagattcgc gaggcgatcg
    12301 agcgcgcccg gcaaaaccgc aatgcaggtc gccgcactat tctttttgtt gacgaagttc
    12361 accgtttcaa caaaagccag caggatgcat ttctgccaca tattgaagac ggcaccatca
    12421 cttttattgg cgcaaccact gaaaacccgt cgtttgagct taattcggca ctgctttccc
    12481 gtgcccgtgt ctatctgttg aaatccctga gtacagagga tattgagcaa gtactaactc
    12541 aggcgatgga agacaaaacc cgtggctatg gtggtcagga tattgttctg ccagatgaaa
    12601 cacgacgcgc cattgctgaa ctggtgaatg gcgacgcgcg ccgggcgtta aatacgctgg
    12661 aaatgatggc ggatatggcc gaagtcgatg atagcggtaa gcgggtcctg aagcctgaat
    12721 tactgaccga aatcgccggt gaacgtagcg cccgctttga taacaaaggc gatcgctttt
    12781 acgatctgat ttccgcactg cataagtcgg tacgtggtag cgcacccgat gcggcgctgt
    12841 actggtatgc gcgaattatt accgctggtg gcgatccgtt atatgtcgcg cgtcgctgtc
    12901 tggcgattgc gtctgaagac gtcggtaatg ccgatccacg ggcgatgcag gtggcaattg
    12961 cggcctggga ttgctttact cgcgttggcc cggcggaagg tgaacgcgcc attgctcagg
    13021 cgattgttta cctggcctgc gcgccaaaaa gcaacgctgt ctacactgcg tttaaagccg
    13081 cgctggccga tgctcgcgaa cgcccggatt atgacgtgcc ggttcatttg cgtaatgcgc
    13141 cgacgaaatt aatgaaggaa atgggctacg ggcaggaata tcgttacgct catgatgaag
    13201 caaacgctta tgctgccggt gaggtttact tcccgccgga aatagcacaa acacactatt
    13261 atttcccgac aaacaggggc cttgaaggca agattggcga aaagctcgcc tggctggctg
    13321 aacaggatca aaatagcccc ataaaacgct accgttaatg ttatcgttgc ggtaatgttg
    13381 ttactgtatc cctgtggtcg caggctgtgg ccacatctcc catttaattc gataagcaca
    13441 ggataagcat gctcgatccc aatctgctgc gtaatgagcc agacgcagtc gctgaaaaac
    13501 tggcacgccg gggctttaag ctggatgtag ataagctggg cgctcttgaa gagcgtcgta
    13561 aagtattgca ggtcaaaacg gaaaacctgc aagcggagcg taactcccga tcgaaatcca
    13621 ttggccaggc gaaagcgcgc ggggaagata tcgagccttt acgtctggaa gtgaacaaac
    13681 tgggcgaaga gctggatgca gcaaaagccg agctggatgc tttacaggct gaaattcgcg
    13741 atatcgcgct gaccatccct aacctgcctg cagatgaagt gccggtaggt aaagacgaaa
    13801 atgacaacgt tgaagtcagc cgctggggta ccccgcgtga gtttgacttt gaagttcgtg
    13861 accacgtgac gctgggtgaa atgcactctg gcctcgactt tgcagctgca gttaagctga
    13921 ctggttcccg ctttgtggta atgaaagggc agattgctcg catgcaccgc gcactgtcgc
    13981 agtttatgct ggatctgcat accgaacagc atggctacag tgagaactat gttccgtacc
    14041 tggttaacca ggacacgctg tacggtacgg gtcaactgcc gaaatttgct ggcgatctgt
    14101 tccatactcg tccgctggaa gaagaagcag acaccagtaa ctatgcgctg atcccaacgg
    14161 cagaagttcc gctgactaac ctggtgcgcg gtgaaatcat cgatgaagat gatctgccaa
    14221 ttaagatgac cgcccacacc ccatgcttcc gttctgaagc cggttcatat ggtcgtgaca
    14281 cccgtggtct gatccgtatg caccagttcg acaaagttga aatggtgcag atcgtgcgcc
    14341 cagaagactc aatggcggcg ctggaagaga tgactggtca tgcagaaaaa gtcctgcagt
    14401 tgctgggcct gccgtaccgt aaaatcatcc tttgcactgg cgacatgggc tttggcgctt
    14461 gcaaaactta cgacctggaa gtatggatcc cggcacagaa cacctaccgt gagatctctt
    14521 cctgctccaa cgtttgggat ttccaggcac gtcgtatgca ggcacgttgc cgcagcaagt
    14581 cggacaagaa aacccgtctg gttcataccc tgaacggttc tggtctggct gttggtcgta
    14641 cgctggttgc agtaatggaa aactatcagc aggctgatgg tcgtattgaa gtaccagaag
    14701 ttctgcgtcc gtatatgaac ggactggaat atattggcta atacccaatt tttctgaatc
    14761 taaaaagcgc ctgcgggcgc tttttttgtc tccctttgat accgaacaat aattactcct
    14821 cacttacacg taatactact ttcgagtgaa aatctaccta tctctttgat tttcaaatta
    14881 ttcgatgtat acaagcctat atagcgaact gctatagaaa taattacaca atacggtttg
    14941 ttactggaat caatcgtgag caagcttgag tgagccatta tgaaaacgaa aatccctgat
    15001 gcggtattgg ctgctgaggt gagtcgccgt ggtttggtaa aaacgacagc gatcggcggc
    15061 ctggcaatgg ccagcagcgc attaacatta ccttttagtc ggattgcgca cgctgtcgat
    15121 agcgccattc caacaaaatc agacgaaaag gttatctgga gcgcctgtac agttaactgt
    15181 ggtagtcgct gcccgctacg tatgcacgtc gtggacggtg aaatcaaata tgtcgaaacg
    15241 gacaataccg gcgatgacaa ttacgacggc ctgcaccagg ttcgcgcctg cctgcgtggg
    15301 cgttccatgc gtcgccgtgt ctacaatccg gaccgcctga aatatccgat gaaacgagtc
    15361 ggggcgcgcg gtgaaggcaa attcgagcgc attagctggg aagaagccta cgacatcatc
    15421 gcgaccaata tgcagcgcct gatcaaagag tacggcaacg agtctatcta tctgaactat
    15481 ggcaccggta cgctgggcgg caccatgacc cgctcctggc cgccgggaaa taccctggtc
    15541 gcgcggctga tgaactgctg cggcggctat ctgaaccatt acggcgacta ctcctccgcg
    15601 caaattgcgg aaggtttgaa ctatacctac ggcggctggg cagatggcaa cagcccgtcg
    15661 gatatcgaaa acagtaagct ggtagtgctg tttggtaata accctggcga aacgcgaatg
    15721 agtggcggtg gggtgactta ctatcttgaa caggcacgcc agaaatctaa tgcccgcatg
    15781 atcatcatcg atccgcgcta taccgacacc ggtgccgggc gcgaagatga gtggatccct
    15841 attcgtccgg gaacagatgc cgcactggtt aacggtctgg cgtacgtcat gatcactgaa
    15901 aacctggtgg atcaggcatt cctcgataaa tattgcgttg gctacgatga gaaaaccctg
    15961 ccagccagtg cgccgaaaaa tggccactat aaagcttata ttctgggtga agggccagat
    16021 ggcgtggcta aaacgccgga atgggcctcg caaatcactg gtgttccggc agacaaaatc
    16081 atcaaattgg ctcgtgaaat cggtagtacc aaaccggcgt ttatcagcca gggatggggc
    16141 ccgcagcgtc acgctaacgg tgaaatcgca acccgtgcta tctcgatgct ggcgattctg
    16201 accggtaacg ttggtattaa cggaggcaac agcggcgcgc gtgaaggttc atacagctta
    16261 ccgtttgtcc gtatgccgac cttggaaaac ccgatccaga ccagcatttc gatgtttatg
    16321 tggaccgatg ccattgaacg tggcccggaa atgacggcgc tgcgtgatgg tgtacgcggg
    16381 aaagataagc tggatgtgcc gatcaaaatg atctggaact atgccggtaa ctgcctgatt
    16441 aaccagcatt ctgaaatcaa ccgtacccat gaaatccttc aggatgataa gaagtgcgag
    16501 ctgattgtgg ttatcgactg ccacatgacc tcatcggcga aatatgctga catcctgctg
    16561 cctgactgca ccgcttccga acagatggac tttgcgctgg atgcatcctg cgggaatatg
    16621 tcttacgtga ttttcaacga tcaggtgatt aaaccgcgct ttgaatgtaa gaccatctat
    16681 gaaatgacca gcgaactggc aaaacgtctt ggcgttgagc aacagtttac tgaaggccgt
    16741 acccaggaag agtggatgcg gcatctgtat gcccagtcgc gggaagcgat tcctgaactg
    16801 ccaacgtttg aagagttccg caagcagggg atctttaaaa agcgcgaccc acaagggcat
    16861 cacgttgctt ataaagcctt ccgtgaagat ccgcaggcaa acccactgac tacgccatcg
    16921 ggcaaaattg agatttattc gcaggcgctg gctgacattg ccgctacctg ggaattgcct
    16981 gaaggcgatg tgatcgatcc actgccgatc tacacgccgg gctttgaaag ttatcaggat
    17041 ccgctgaaca aacagtatcc gctgcagctt acaggtttcc actataaatc tcgcgttcac
    17101 tcaacttacg gcaacgttga tgtgctgaaa gcggcttgcc gtcaggaaat gtggatcaac
    17161 ccgcttgatg cccaaaaacg cggtatccac aacggcgata aagtcaggat ctttaacgat
    17221 cgtggtgagg ttcatattga ggcgaaagtg acgccacgaa tgatgccggg tgtggtcgca
    17281 ctgggtgaag gtgcctggta tgacccggat gcaaaacgtg tcgataaggg tggttgtatt
    17341 aacgtactga ccactcaacg tccgtctcct ctcgctaagg ggaatccgtc acatacaaac
    17401 cttgttcagg ttgaaaaggt gtaaggagta accgatgaca acccagtatg gattttttat
    17461 tgattccagc cgttgcaccg gttgcaaaac ctgcgagctg gcctgtaaag actacaaaga
    17521 tttgacgcca gaagtcagct tccgccgcat ttatgaatat gctggcggcg actggcagga
    17581 agataacggt gtctggcacc agaacgtgtt tgcctactat ctgtcgattt catgtaacca
    17641 ctgcgaagat ccggcttgta ctaaagtctg cccgagcggt gcgatgcata aacgtgaaga
    17701 tggttttgtt gtggtcgatg aagatgtgtg cattggctgc cgctactgcc atatggcttg
    17761 cccgtatggc gcaccgcaat ataacgaaac gaaaggccat atgaccaaat gcgatggttg
    17821 ttatgaccgt gttgcggagg gtaaaaagcc gatctgtgtt gaatcttgtc cgctgcgggc
    17881 gctggatttc ggccctatcg acgagctgcg taaaaaacat ggcgatctgg cggccgttgc
    17941 gccgttgccg cgagctcact ttaccaaacc gaatattgtg atcaaaccca atgccaatag
    18001 ccgcccgacc ggggatacca ctggctatct ggcaaacccg aaggaggtgt gagatgggaa
    18061 gtggatggca tgaatggccg ctgatgatct tcacggtctt cgggcaatgt gtagcaggtg
    18121 gttttatcgt tctggctttg gcgctgctca aaggcgacct gcgagcagaa gcccagcagc
    18181 gtgttatcgc ctgcatgttt ggtttatggg tgctgatggg cattggcttt atcgcctcta
    18241 tgctccatct tggttcacca atgcgcgctt ttaactcgct caaccgggta ggggcttcag
    18301 cactcagtaa cgaaatcgcc agcggttcga tcttttttgc cgtaggcggc atcggctggt
    18361 tgctggcaat gctgaaaaag ctgtcaccgg cattgcgtac gctgtggctg atagtgacga
    18421 tggttcttgg cgtcatcttt gtctggatga tggtgcgtgt gtataacagc attgataccg
    18481 ttccgacctg gtacagcatc tggacgccga tgggcttctt cctgacgatg tttatgggcg
    18541 gcccgttact gggttacctg ttgttgagtc tggctggcgt cgatggctgg gcgatgcgtc
    18601 tgctgccagc aatttctgta ctggcactgg tagtgagtgg cgtggtgtca gtgatgcagg
    18661 gcgcagagct ggcgactatt catagttctg tgcagcaggc cgcagcgctg gtgccggact
    18721 atggtgcgct gatgtcctgg cggatcgtgc ttttggccgt tgccctgtgc ttgtggattg
    18781 caccacagct aaaaggttat cagcctgcgg ttccgctact ttctgtatca ttcattctgc
    18841 ttctggcagg ggaattaatc ggtcgcggcg tattctatgg tttgcatatg accgtgggga
    18901 tggccgtcgc aagctaatca taacaaccgg ggtttcggcc ccggttctct tttatttctg
    18961 cttcgttaac gtgtcataac tggtcatcaa attacgataa tcaggaatgt ggttagagaa
    19021 caacgtcgcc agtccttcaa tatcattacg ccagtcgcga tgcagctcgc acgccacgcc
    19081 gaaccatgtc atcaattgcg caccagcttg cgacaagcga tcccatgccg aatgccgggt
    19141 aatttcatta aaggtccctg acgcgtcagt cacgacaaag acgtcaaacc cttcttcaat
    19201 ggctgaaagc gccgggaatg ccacgcaaac ttcggttacc acaccggcaa taattaactg
    19261 ttttttacct gtcgctttga cagcttttac aaaatcttcg ttatcccagg cgttaatatt
    19321 tcccgggcga gcaatgtaag gtgtatcggg gaattgtgct ttcagttctg gaactaatgg
    19381 gccgttagga ccggtttcaa aactggtggt aagaatagtt ggtaagttga aatacttagc
    19441 caggtcaccc agcgccagca cgttattttt aaacttatcg ggttcgatat cccgtacaag
    19501 ggaaagtaaa ccagcctggt gatcaacaag caaaacggca gcatcatttt tatcaagacg
    19561 aacatacggt ttggtcatcc tcttctcctt tcgagagtca gtggtacgtc tgaaatcgat
    19621 cagacgcgat gcattgctct gaaagcatag acgggaaata tgagtttgct gtgaccatga
    19681 aatttttcga ctgaacgaag cgtatgaaat ttgtgttagt tcaataaaaa caatcagatg
    19741 agactaatca tctcttcagc attagcgtta tgaatgagta atataaatcg ataataccgc
    19801 cgctgggata tcgcgtattt tcacccattg acaatgtttt tggcggtggc atgatgcgca
    19861 tgaaatttga acttcctcac ggttttaatt catgtccacg tatacccagc ctgtcatgct
    19921 tttgctgtct ggcctgcttt tgttgactct ggcgattgcg gtgttaaata cactcgtgcc
    19981 gctttggctc gcccaggaac acatgtccac atggcaggta ggcgttgtca gctcatccta
    20041 ttttaccggc aaccttgtcg gtacattgct gacagggtat gtcattaagc gcattggctt
    20101 taaccgcagc tattatctgg cctccttcat ttttgccgct ggctgtgccg gccttggcct
    20161 gatgattgga ttctggagct ggttggcttg gcgttttgtc gcgggcgtcg gctgtgccat
    20221 gatttgggtg gttgttgaga gcgcgctgat gtgcagtggg acgtcacgta accgtgggcg
    20281 tttgcttgct gcgtatatga tggtttatta cgtgggaacg tttttaggcc agttactggt
    20341 cagcaaagtt tcaaccgagc tgatgtccgt attgccgtgg gttacaggtt tgacgttggc
    20401 agggatctta ccgctgttgt ttacgcgtgt gctgaatcag caggctgaaa accatgattc
    20461 gacgtcaatt acgtcaatgc taaaactccg tcaggcgcgg cttggcgtga atggctgcat
    20521 tatctcagga atcgttctgg gatctctata tggcctgatg ccgctgtacc tcaatcacaa
    20581 aggggtgagc aatgccagca ttggtttctg gatggcggta ctggtcagtg cgggtatcct
    20641 tggacaatgg ccgattggac gtctggcgga taagtttggt cgactgctgg tgttgcgtgt
    20701 tcaggtcttt gtcgtcattc tcggcagtat cgcgatgctt agccaggcgg cgatggcccc
    20761 agcgttattc atcctcggtg ccgctggctt tacgctatat ccggtggcga tggcatgggc
    20821 ttgcgagaaa gttgaacatc atcaactggt ggcgatgaac caggccttac tgttgagcta
    20881 tactgtggga agtctgcttg gcccgtcatt taccgctatg ctaatgcaga atttctccga
    20941 taatttattg tttatcatga tcgccagcgt atcgtttatc tatttgctga tgctgctgcg
    21001 caacgccggt catacgccga aacccgttgc tcacgtgtaa atgaattcaa gcagagtgtg
    21061 aacttactgt ttcacactct gcttttttgt ttcttctatc tgacttgctt tattccaaat
    21121 tttattcgtt taaaaataaa atgtgcagca ggttataatt ttgcatttcg ctatttccgc
    21181 acttcttatt tgccgcgcat aatccctcgt tttacagatg cccctttaat tttggcgaag
    21241 gatttgtcta tggctgggaa tgttcaggaa aaacagttgc gatggtacaa cattgcgctg
    21301 atgtctttta tcactgtctg gggttttggc aacgttgtta ataactatgc caaccagggg
    21361 ctggtggttg ttttttcatg ggtgtttatc tttgcactct atttcacacc ttatgcgcta
    21421 attgttggtc agttaggctc gaccttcaaa gatgggaagg gcggggtcag tacctggatt
    21481 aaacacacga tgggacccgg actggcttat ctcgccgcgt ggacctactg ggtggtgcat
    21541 attccctatc tggcacaaaa accccaggca attctgattg cgctcggttg ggcgatgaaa
    21601 ggcgacggtt cgctaatcaa agaatattca gtcgtagcgt tacaggggtt aacgctggtg
    21661 ctgtttatct tctttatgtg ggttgcttca cgcggtatga aatcgctgaa aatcgtcggt
    21721 tctgtggcag ggattgctat gtttgttatg tcgctcctgt atgtggcgat ggcggtaacc
    21781 gcgcctgcaa ttactgaagt gcatattgcg accacaaaca ttacctggga aacgttcatt
    21841 cctcatatcg actttaccta cattaccact atttcaatgc tggttttcgc ggttggcgga
    21901 gcagagaaga tttctcctta cgttaatcaa acgcgcaacc caggaaaaga atttccaaaa
    21961 gggatgttat gcctggcggt gatggttgcg gtttgtgcca ttctgggctc gctggcgatg
    22021 gggatgatgt ttgattcgcg taatatcccg gatgacttaa tgaccaacgg tcagtattac
    22081 gcctttcaga agctgggcga gtattacaac atgggtaata ctttaatggt gatttacgcc
    22141 attgcgaata ccctgggaca agtagcggcg ctggtattct cgattgatgc cccgcttaaa
    22201 gtgctattag gtgatgctga cagcaaatat attccagcca gtttatgtcg taccaacgct
    22261 tctggtacgc ccgttaatgg ctattttctg accctggtac tggtggcgat tctgattatg
    22321 ctgccgactc tcggcattgg tgatatgaac aatctctata aatggctgtt gaaccttaat
    22381 tcggtagtga tgccgctgcg ttatttatgg gtatttgttg catttattgc agtcgttcgc
    22441 ttggcgcaga aatataaacc agaatatgtc tttattcgta ataagcctct ggcaatgacc
    22501 gtcgggattt ggtgttttgc ctttaccgcc tttgcctgtt tgacggggat cttcccgaaa
    22561 atggaagcct tcactgcaga gtggaccttc cagttggcgc tgaatgttgc aacgccgttt
    22621 gtgctggtag gattaggact gatattcccg ctgctggcgc gtaaagcgaa tagtaaataa
    22681 ttattgtggt cggtgacgct gactctggca gatctgaccc gtttttacat aatcgagaaa
    22741 tgcgcgcaag ccgcaggaca tatactggcg gtttggataa tagatctgga agcctggacg
    22801 ctctgtgctc cagtcttcca gtacacattc taaacgacca gtatcaaggt actccttgat
    22861 ctgttcatag agcagatacc cgataccagc acccatcaaa acggcctcca gttcagcatc
    22921 aacatcatcc agaatgatat ttcctgcgac agcaatttcc agctcctttg caaattgcca
    22981 gtggaaaggt ttgccgctgg gataacgaaa aacaacacat tgatgattaa gcagatcatg
    23041 aggatggcgg ggtttgccat atcttgcaaa gtactctggc gttgctgcta cacataattt
    23101 cactggcggg ccgatcgcca cgctgatcat atctttttcg acgatgcaac taagtcgaac
    23161 gccagcgtca aagccctgtt ggacgatatc gacaagagag tcgtcagttg tgagctcgac
    23221 tttaatatca ggatattcac gtgtgaaacc aaccagtaaa gacattaaaa atatacgtgc
    23281 agctacccgg gcggcattga ttttgagcgt tcctgtcggt gtcagacgaa aatcattcat
    23341 ctcatctaac atgatctgaa tttcgtcgaa agctgggcgc aatcgttcat agagattaga
    23401 acccgcttcc gttaacgata cgcttcgggt tgtccgattg aataagcgaa ttttaagacg
    23461 ttgttccagt gttttaatac tatggctaat ggcggacgag gataagccta actcatcgcc
    23521 cgctgcacga aagctttgat tacgggccac ggcaaagaaa gtggcaaagt cagacatatt
    23581 catccgcatt agtgaaaatc cttcattaac tcatcctgaa tcatcacgtt tacaggatta
    23641 tgccgcctgc gtaaagtgcg ctccagaact taacgtggag gtaaaattat gcagtctgaa
    23701 cgtatttatt tggtatgggc ccatcctcgt catgattcat tgaccgcaca tattgctgat
    23761 gcgatccatc agcgggcaat ggagcggaaa atacaggtga cggaactcga tttatatcgg
    23821 cgtaatttca acccagtgat gacgccggaa gatgaaccag actggaagaa tatggataaa
    23881 cgttattctc cagaggttca tcagctttat tcagagctgc ttgaacatga cacgttagtg
    23941 gtggtttttc ctctctggtg gtacagcttc ccggcaatgc taaaaggata tattgacaga
    24001 gtatggaata atgggctggc ttatggagat gggcacaaat taccattcaa taaagttcgt
    24061 tgggtggcgc tggttggagg agacaaagaa tcatttgtcc agatgggctg ggaaaaaaat
    24121 ataagcgatt atttaaaaaa tatgtgcagt tatcttggta ttgaagatgc cgatgtcact
    24181 ttcttgtgta atacagtggt attcgatggg gaagaacttc acgcgagcta ttatcagtcg
    24241 ttattatctc aggtacggga tatggtagat gcactataag atgtgttaaa aacgctgtag
    24301 cagaatgaag cgcggaataa aaaagcggca actcaataaa gttgccgctt tacggggaaa
    24361 ttagaacatt accttatgac cgtactgctc aagaatgcct ttcacgcgtt ccatggtctc
    24421 tttcttcggt ggtttaacac cgtcgagttt gtactcttca cccattgcca cccatttgtg
    24481 tttgcccagc tcgtggtagg ggagaagctc gattttctca acgttgccca tatcacgggt
    24541 aaattcaccg aggcgatgcg ctgaatcgtc atcgtcagac cagcctggga caacaacgta
    24601 gcggatccac accttcacat ttttgttcgc cagatattta gcgaactcca gcgtgcggtg
    24661 gttggaaact ccaaccagat tttggtggat ctcgtcgttc atctgtttga gatcgagcat
    24721 taccaggtcg gttacttcca gcagttcatc aatcaccgga tcgtaacgac gaacaaaacc
    24781 gttggtgtcc agacaggtat gaatgccttc ttttttgcag gcgcggaacc agtcacgaac
    24841 aaactcagct tgcaggattg cttcaccgcc ggatgcggta acgccgccgc cggaagcgtt
    24901 cataaagtgg cgataggtca ccacttcctt catcaaatct tcaacggtaa cttctttacc
    24961 gccatgcgtg tcccaggtgt cgcggttatg acaatacagg cagcgcatca ggcagccctg
    25021 gaaaaaggtg ataaagcgaa tacctgggcc gtctacggtt ccacaggatt caaaggagtg
    25081 aatgcgacca ataactgact tggtagcccc cgccgtagcg gtattttctg ttgtattaca
    25141 attagttaaa ttactcatat cgcttcaatt ggctctagtt aactctggtt tatggacgca
    25201 ttatggacat tcctgacacc gggttaagag tcacagcatc ttgtaagaaa tccggtgcaa
    25261 agtgtgcgta ggtcatagtt tgctgaatgt tagaatgacc caggatgcgc tgcaatgtga
    25321 ttatgttacc tccattcatt ataaaatgtg tggcaaatgt atgcctcaaa acatgtactg
    25381 cttgtccgtc aggtaaatcg ggttttactt ccctgagagc gttacgcact ttgtagtaac
    25441 tggcattaaa aagcctgcct gaatttttgg tcttgatccg tttaatcagg tcctgcgaaa
    25501 cgggaattgt cctgcgtttt ccgtttttag ttttcataaa cgtaaccatc tggttaatga
    25561 tgtgttcagc ttttaaatta gacacttcac tccagcgtcc accagtagaa aggcagacca
    25621 gagttgcatt taattcatca ccatcaagca tggataacag ccgcgtaatc tcttcactgg
    25681 acaaaaaagc catttccgta acagcttcac gtaaccgttt aatctcacgg aacgggttgt
    25741 gggagtggta ttcaccggcg tcaattaact tggtgaacat cccgctcatt attgccagat
    25801 gtcgatttac gctggctggt tttagaccat cgttcatcat tacaacgcga taatcagtta
    25861 tcgttttctt tgttagctgg tcagctctgg acactcccat ttctgcaaat ttggcgatta
    25921 ttgtcgttaa acgcccccgt tcaatatctc cacgctcatg tgattttccg tgatatatcc
    25981 accatctacc taacaactct gtaagagttc ggcggtcggc tggtttctcc aaccactctt
    26041 tgttgtggta gttaaccagt acatgacgtt cgaatgcctg agcttcacct ttagttttaa
    26101 atttccgcct gatacgtttt ccatctgcac cctgcggtct gacgtccact tcataacgac
    26161 catcatcgag ctttttaata gacataaagc cctccgatga cgctgtttac ttctactact
    26221 tgaaaattaa tgcaattttc tttcgtacat ttactacaca catatgctga ataaatcgtc
    26281 agccagtctt ctggtctgag tggtgcaagg ttgttgagtc ttgcccaatg tgtgcgagag
    26341 ccggggctat ttgtccagct gctggatctg tttcatcaaa catgaaccag tcacgatact
    26401 tgcgaaagcg tggatgctta aacagcttca tacctgcttc cataggcatt tttgattttc
    26461 ctgattcata tccatgatat gtgtagtaat taattccaat taattcagca agttccttag
    26521 ttttaaggcg ttcggattca cggatgagct ttagtttctc actttgttca cttgacataa
    26581 ttttgctaat ctccaattat attgctactt ggcaatttgt gattcactca aaaaggctct
    26641 agatggctcc agttggtgaa tcgcaaatct tatggaggat agcaaagtga cgacaaatgt
    26701 agaaatttct tgtccaacta gcgatgaggc aagtttcgaa aatgaagcca aacgtaaaag
    26761 cattcagatt tcagagcgcc catctgattt gctgtcgaaa gaaggttttg ctctttacat
    26821 tggtaagaca ccacgcgcgg tggctgaaat ggctaaagca ggaaagctgc cagccttcta
    26881 catgacagac ccattaaaac caagagggaa agctgaatta tggattaatc gccgtgagtg
    26941 ggacaagtac gcagcccaac tggttgatga agctccgaca gaatggcatg actggaaaaa
    27001 tcgcattagt tacagcaaat caagacatgg ccgtgcggct taaggtggaa aggatgaacg
    27061 agcctcgttg tattgctcag ttactgcgta acgaaagccc cagggcgatt gacttcacca
    27121 tcacccacgg gaagggtcgc aagggaatca ttatccgcac caaaaaacag agtccgttaa
    27181 aaaaggctct gacctttctg aaaagccgga gggtctggaa atgacagtga tgacgctcaa
    27241 tctcgtcgaa aaacagccag cagctatgcg ccggataatt ggcaagcatc ttgccgtccc
    27301 tcgctggcag gatacatgtg attattataa tcagatgatg gagcgcgaac ggttaacggt
    27361 ttgctttcat gcgcagttaa aacagcgtca cgcaacgatg cgttttgaag aaatgaacga
    27421 cgtcgaacgt gaacggctgg tttgtgcaat tgatgaactg cgtggggcat tctcaaaacg
    27481 ccgtcaggtc ggtgcaagtg agtatgcata tattagtttt ttaacagtca gtcagcgtcg
    27541 tactttattt atgcatgcgg gattgacaga aaaagaattc aatcagccgt actggcgcat
    27601 taatgaagaa tcatgttact ggcgtgatgc tttattccgt gcattacgtg aattattcag
    27661 tctgtttgag tatgcaccga caattctgac gtcggtaaaa ccagagcaat atctgcatta
    27721 agtaattaac cagagttttt aacgcactta atcgtgcggg gcttcttttt gcctggagaa
    27781 agtcatgcat acagtttctg aaaatcagtg cggtaaatac acattactgc tgcaacaggc
    27841 cagaaccgaa gcacaggccg acgctgcgac gcgcttttct tctcatcttg atgccatgat
    27901 tcgccacatc acaaaggcgg agttatcccg cgtggagata gtcgagctgc tcagtcagga
    27961 gtcggaaaaa tttcacaata tcggattgtc tcgcggggag gtgctttgat gtcctgttct
    28021 cattcagttg tattactgaa taacgcctta aaaatcgccg ttatgaaaaa tggcgatttg
    28081 tctcttattc aactttgcct tgataaagaa aaacgcgaca taactgaatc tgttatcgcg
    28141 atttatcaga atgaattaaa cctcctgtct gatgtggtca atttacttgt taaacgcgct
    28201 gtattccaca agcaaatttc ctcagtggat gaactgacaa aattaacgac agaacttgcc
    28261 agttattgcg ctgatgtatc caggaaactt aacgataaaa ggagctgata atgccggaca
    28321 acgtagattt cattcaggaa caacaggctg aattactgga gcgtcagatt aacgcggcaa
    28381 gggtaaaaca ttgcggtgct tctgcgctgg tttgcgaaga gtgtgacgcg ccaatacctg
    28441 ctgcccgtcg tgcggcttat ccgtcagcca cgcgttgtgt ttcctgccag tcagtctttg
    28501 aagcaaaaaa caagcattac cggagaatgg catgagtatt cgtattgaaa ttggcgaacg
    28561 ttatgtcgtt accagtgaca gctttcagtt tattctccac gagaaaaaga gagcggaaag
    28621 cggtaaaaac gccggtcagg aatggctggc ggtggttggt tattatccga aattaagcca
    28681 gctcgtttct ggcctgatgc atcacgatat tctgaccgga agcgcaaagt cttttgctga
    28741 tttaaacgcg caggttgagc aactcagcag gcgttgttca gaggcttttg gctcatatgg
    28801 ccgttaaagc ctccgggcgt tttgtccctc cttcagcatt tgctgcaggc accggtaagg
    28861 cgtttaccgg tgcttatgca tggaacgcgc cacgcgaggc cgtcgggcgc gaaagacccc
    28921 ttacacgtga cgagatgcgt caggtgcaag gtgttttatc cacgattaac cgcctgcctt
    28981 actttttgcg ttcgctgttt acttcacgct atgactacat ccggcgcaat aaaagcccgg
    29041 tgcacgggtt ttatttcctc acatccactt ttcagcgtcg tttatggccg cgcattgagc
    29101 gcgtgaatca gcgccatgaa atgaacaccg acgcgtcgtt gctgtttctg gcagagcgtg
    29161 accattatgc gcgtctgccg gggatgaatg ataaggagct gaaaaagttt gccgcccgta
    29221 tttcatcgca gcttttcatg atgtatgagg aactctgcga tgcctgggtg gatgcgcatg
    29281 gcgaaaaaga atcgctgttt acggatgagg cgcaggctca cctctatggt catgttgctg
    29341 gcgctgcacg tgctttcaat atttcccctc tctactggaa aaaataccgt aaaggacaga
    29401 tgaccacgag gcaggcatat tctgccattg cccgcctgtt taacgatgag tggtggatta
    29461 gtcagcttaa aggccagcgt atgcgctggc atgaggcgtt actgattgct gtcggggagg
    29521 tcaataaaga ccgttcacct tatgccagta aacatgccat tcgtgatgtg cgtgcgcgcc
    29581 gccaggcaaa tctggaattt cttaaatcgt gtgaccttga aaacagggaa accggcgagc
    29641 gcatcgacct tatcagtaag gtgatgggca gtatttctaa tcctgaaatt cgccggatgg
    29701 agctgatgaa caccattgcc ggtattgagc gttacgccgc agcagagggt gatgtgggga
    29761 tgtttatcac gctgaccgcg ccgtcaaagt atcacccgac acgtcaggtc agaaaaggcg
    29821 aaagtaaaac cgtccagcta aatcacggct ggaacgatga ggcatttaat ccaaaggatg
    29881 cgcagcgtta tctctgccgt atctggagcc tgatgcgcac ggcattcaag gataatgatt
    29941 tacaggtcta cggtttgcgt gtcgtcgagc cacaccacga cggaacgccg cactggcata
    30001 tgatgctttt ttgtaatccg cgccagcgta accagattat cgaaatcatg cgtcgctacg
    30061 cgctcaaaga ggatggcgac gaaagaggag ctgcgcgaaa ccgttttcag gcaaaacacc
    30121 ttaaccgggg cggtgctgcg ggatatatcg cgaaatacat ctcaaaaaac atcgatggct
    30181 atgcactgga tggtcagctc gataacgata ccggcaggcc gctgaaagac actgccgcgg
    30241 ctgttaccgc atgggcgtca acgtggcgca ttccgcaatt taaaacggtt ggcctgccga
    30301 caatgggggc ttaccgtgaa ctacgcaaat tgccgcgcgg cgtcagcatt gctgatgagt
    30361 ttgacgagcg cgtcgaggct gcacgcgccg ccgcagacag tggtgatttt gcgttgtata
    30421 tcagcgcgca gggtggggca aatgtcccgc gcgattgtca gactgtcaga gtcgcccgta
    30481 gcccgtcgga tgaagttaac gagtacgagg aagaagtcga gagagtggtc ggcatttacg
    30541 cgccgcatct cggcgcgcgt catattcata tcaccagaac gacggactgg cgcattgtgc
    30601 cgaaagttcc ggtcgttgag cctttgactt taaaaagcgg catcgccgcg cctcggagtc
    30661 ctgtcaataa ctgtggaaag ctcacctgtg gcgatacttc gttaccggct cccacacctt
    30721 ctgagcacgc cgcagcagtg cttaatctgg ttgatgacgg tgttatcgaa tggaatgacc
    30781 cggaggtcgt gagggcgctc aggggcgcat ttaaacacgg gctgagaaca ccaaatcgtc
    30841 agcagagaaa cggaagcccg ttaaaacagt atgaaatggc accatcggcc agactgaccc
    30901 ggtcggaacg aatgcaaatt acccgtatcc gcgttgacct cgctcagaac ggtatcaggc
    30961 cgcagcgatg ggagcttgag gcgctggcgc gtggagcaac cgtaaattat gacgggaaaa
    31021 aattcaccta tctggtagat gaggagtggc tggaggatat aacggatatt aagtggatct
    31081 aatgataatt taactcctcg gaatagaatg ttatgttcgt tcttgataac tgataatgag
    31141 tgatttaaaa aagccatgtt atgttactaa catggctttg ggatattaat tgctgtgctc
    31201 tttaaagaat agattaactt cttcaggtgt tatattttca tccattttat caaatttatc
    31261 tgtgtcaacg atttttgttt ttcttagcaa ggataatatt ttggctttat tgggg
//
LOCUS       DAPHKZ010000047        31225 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.047, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000047 DAPHKZ010000000
VERSION     DAPHKZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31225
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.047"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            113..3865
                     /gene="yfaL"
                     /locus_tag="RH288_002250"
     CDS             113..3865
                     /gene="yfaL"
                     /locus_tag="RH288_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA-I family autotransporter adhesin YfaL/EhaC"
                     /protein_id="HDV4031298.1"
                     /translation="MRIIFLRKEYLSLLPSMIASLFSANGVAAVTDSCQGYDVKASCQ
                     ASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFAN
                     NTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA
                     MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSK
                     HPSGYTIVNNTAFTNNTAEGYGGAIYTNSVTAPYLIDISVDDSYSQNGGVLVDENNSA
                     AGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSG
                     DLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQN
                     QAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGIIEGAGQLTIAQNGSY
                     VLAGAQSMALTGDIVVDDGAVLSLEGDAADLTALQDDPQSIVLNGGVLDLSDFSTWQS
                     GTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANN
                     NSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITSDVDTRSDAAGHG
                     RDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSA
                     VRVEEGTLKGDVADILPYASSLWVGDGATFVTGADQDIQSIDAISSGTIDISDGTVLR
                     LTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNT
                     SGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVN
                     SITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLR
                     SQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAF
                     MMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEW
                     MLGIVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYA
                     WFSNDVSEQEDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAA
                     NRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAV
                     KQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW"
     gene            complement(3993..4715)
                     /locus_tag="RH288_002251"
     CDS             complement(3993..4715)
                     /locus_tag="RH288_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HDV4031299.1"
                     /translation="MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLR
                     LGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNP
                     ITNTFKLGPGVDVNYMLHTQNK"
     gene            4862..7489
                     /gene="gyrA"
                     /locus_tag="RH288_002252"
     CDS             4862..7489
                     /gene="gyrA"
                     /locus_tag="RH288_002252"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HDV4031300.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDP
                     IIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELEL
                     VREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLP
                     LEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDEL
                     IGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRG
                     DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAA
                     EGDDEIAPEVDVDDEPEEE"
     gene            7638..9326
                     /locus_tag="RH288_002253"
     CDS             7638..9326
                     /locus_tag="RH288_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416733.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2138 domain-containing protein"
                     /protein_id="HDV4031301.1"
                     /translation="MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSP
                     LVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIE
                     GSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPL
                     LFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFK
                     DDQQDTEATAIAGDLLSGKKRWQASFGLEERTAEKTPVRQRIVVSARWLGFGYQRLMP
                     SFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAE
                     EMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNI
                     GAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLA
                     MQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGIAKLLRNETLT
                     SLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL"
     gene            9323..9946
                     /locus_tag="RH288_002254"
     CDS             9323..9946
                     /locus_tag="RH288_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1175 domain-containing protein"
                     /protein_id="HDV4031302.1"
                     /translation="MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQ
                     GPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGLSSQYLPPEMTLTPEQRQLAQNW
                     NQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYH
                     TGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR"
     gene            9970..14484
                     /locus_tag="RH288_002255"
     CDS             9970..14484
                     /locus_tag="RH288_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HDV4031303.1"
                     /translation="MGTGLANADDSLPSSNYAPPAGGTFFLLADSSFSSSEEAKVRLE
                     APGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWL
                     WDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLV
                     KQFRYPLWQAKPFEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYR
                     ATTVVFVSDTVALSKVSGKELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGT
                     LQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKV
                     IGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVNVTLDARNGGQGSFRLPENAVAGG
                     YELRLAYRNQVYSSSFRVANYIKPHFEIGLALAKKEFKTGEAVSGKLQLLYPDGEPVK
                     NARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNFPAADKPSRYLL
                     TVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVT
                     YEWLRLEDRTSHSGELPSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGST
                     AHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTL
                     QRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTH
                     YQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRT
                     SSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKA
                     YFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAG
                     LFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQV
                     QDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLD
                     ALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGAR
                     FTWWGEDGNGDAFLTAWAWYADWQASQAIGVTQQPEYWQHMLDSYAEQADNMPLLHRA
                     LVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESPLADA
                     VANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQTAAIL
                     SGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEDWRWVGQGVP
                     DILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSN
                     EIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQL
                     LEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAA
                     GSEWTGMQVK"
     gene            14485..16134
                     /locus_tag="RH288_002256"
     CDS             14485..16134
                     /locus_tag="RH288_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaQ family protein"
                     /protein_id="HDV4031304.1"
                     /translation="MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGV
                     TKVSALSDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRD
                     TALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLA
                     TLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTD
                     GTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKST
                     TAVNPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDRE
                     AKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMTAWT
                     QDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRS
                     TCQLLPKAKAWLAKKMPQWRRILQAETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRN
                     FFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD"
     gene            16139..16915
                     /locus_tag="RH288_002257"
     CDS             16139..16915
                     /locus_tag="RH288_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaP family protein"
                     /protein_id="HDV4031305.1"
                     /translation="MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASF
                     SQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSF
                     ARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHV
                     VTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPIHGRYQVYINYYGGRSETE
                     LTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW"
     gene            complement(16989..18173)
                     /gene="atoB"
                     /locus_tag="RH288_002258"
     CDS             complement(16989..18173)
                     /gene="atoB"
                     /locus_tag="RH288_002258"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA acetyltransferase"
                     /protein_id="HDV4031306.1"
                     /translation="MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKID
                     SQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAI
                     QAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGI
                     TAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDE
                     FPKADSTTEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARI
                     KSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFD
                     SEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIER
                     LN"
     gene            complement(18204..19526)
                     /locus_tag="RH288_002259"
     CDS             complement(18204..19526)
                     /locus_tag="RH288_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00366 family protein"
                     /protein_id="HDV4031307.1"
                     /translation="MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPI
                     SMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVT
                     FFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPL
                     LAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPK
                     LLMEEADFQKQLPKDAPPSERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNL
                     MFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFI
                     NVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYG
                     EQWMNMAQPFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF"
     gene            complement(19523..20173)
                     /gene="atoA"
                     /locus_tag="RH288_002260"
     CDS             complement(19523..20173)
                     /gene="atoA"
                     /locus_tag="RH288_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate CoA-transferase subunit beta"
                     /protein_id="HDV4031308.1"
                     /translation="MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQ
                     SENGFLGLGPVTTAHPDLVNAGGQPCGVLPGAAMFDSAMSFALIRGGHIDACVLGGLQ
                     VDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTA
                     QHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL"
     gene            complement(20173..20835)
                     /gene="atoD"
                     /locus_tag="RH288_002261"
     CDS             complement(20173..20835)
                     /gene="atoD"
                     /locus_tag="RH288_002261"
                     /EC_number="2.8.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate CoA-transferase subunit alpha"
                     /protein_id="HDV4031309.1"
                     /translation="MKTKLMTLQDATGFFRDGMTIMVGGFMGIGTPSRLVEALLESGV
                     RDLTLIANDTAFVDTGIGPLIVNGRVRKVIASHIGTNPETGRRMISGEMDVVLVPQGT
                     LIEQIRCGGAGLGGFLTPTGVGTVVEEGKQTLTLDGKTWLLERPLRADLALIRAHRCD
                     TLGNLTYQLSARNFNPLIALAADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQE
                     SK"
     gene            complement(21031..22416)
                     /gene="atoC"
                     /locus_tag="RH288_002262"
     CDS             complement(21031..22416)
                     /gene="atoC"
                     /locus_tag="RH288_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetate metabolism transcriptional
                     regulator AtoC"
                     /protein_id="HDV4031310.1"
                     /translation="MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLF
                     ADIHPDVVLMDIRMPEMDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDY
                     VIKPFDLDELNLIVQRALQLQSMKKEIRHLHQALSTSWQWGHILTNSPAMMDICKDTA
                     KIALSQASVLISGESGTGKELIARAIHYNSRRVKGPFIKVNCAALPESLLESELFGHE
                     KGAFTGAQTLRQGLFERANEGTLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIK
                     VDIRIIAATNRDLQAMVKEGTFREDLFYRLNVIHLILPPLRDRREDISLLANHFLQKF
                     SSENQRDIIDIDPMAMSLLTAWSWPGNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQ
                     PDCNAGEVKTAPVGERNLKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYK
                     LQEYGIDPADV"
     gene            complement(22413..24239)
                     /gene="atoS"
                     /locus_tag="RH288_002263"
     CDS             complement(22413..24239)
                     /gene="atoS"
                     /locus_tag="RH288_002263"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     AtoS"
                     /protein_id="HDV4031311.1"
                     /translation="MHHMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVL
                     SEKEKKLSAVVNLLNQALGNRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAG
                     YYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMI
                     PIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANI
                     DIITDGLSTLAQNIPTRLPQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVI
                     AIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALE
                     ISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGEL
                     MAGVAHEVRNPLTAIRGYVQILRQQTSDPIHQEYLSVVLKEIDSINKVIQQLLEFSRP
                     RHSQWQQVSLNALVEETLVLVQTAGVQARVDFISELDNELSPINADRELLKQVLLNIL
                     INAVQAISARGKIRIQTWQYSDSQQAISIEDNGCGIDLSLQKKIFDPFFTTKASGTGL
                     GLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV"
     gene            24406..27255
                     /gene="rcsC"
                     /locus_tag="RH288_002264"
     CDS             24406..27255
                     /gene="rcsC"
                     /locus_tag="RH288_002264"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HDV4031312.1"
                     /translation="MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPAF
                     EPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANR
                     LQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSW
                     FGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLA
                     RMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQE
                     PTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARI
                     YLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDVIKQTLTLYAERVRKSRDS"
     gene            complement(27455..28105)
                     /gene="rcsB"
                     /locus_tag="RH288_002265"
     CDS             complement(27455..28105)
                     /gene="rcsB"
                     /locus_tag="RH288_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HDV4031313.1"
                     /translation="MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD"
     gene            complement(28122..30794)
                     /gene="rcsD"
                     /locus_tag="RH288_002266"
     CDS             complement(28122..30794)
                     /gene="rcsD"
                     /locus_tag="RH288_002266"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HDV4031314.1"
                     /translation="MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIQKRVDNWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLIST
                     LPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGNNDNEKEGTDSVSIHFNS
                     TKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFS
                     SRSTENVPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHL
                     NLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRMIFMKNIGDALKEPAQSLAESAAKLNAPESKQLANQADVLVRLVDE
                     IQLANMLADDSWKSETVLFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGD
                     RDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLH
                     FPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPE
                     VEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNP
                     SNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLG
                     GDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPG
                     KQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL"
BASE COUNT         7630 a         7685 c         8394 g         7516 t
ORIGIN      
        1 taataacaaa atagccattg caccgggttg aacaatttac aaaagaaaga tattccatat
       61 cgtataatgc gattaaatac gccgtcttat agaaaatgat ggttagatta atatgcggat
      121 tatctttcta cgcaaggagt atttatcttt actcccgtca atgattgcat ctcttttctc
      181 tgctaacggt gtcgcggcgg tcactgattc atgccaggga tatgatgtca aagcgagttg
      241 tcaggccagc aggcaaagcc tttcaggcat tacgcaggac tggagtatcg ctgatgggca
      301 atggctggtt ttttcggata tgaccaataa cgccagcggt ggggccgtat ttttgcaaca
      361 aggagcggaa ttttcactat taccagaaaa tgaaactgga atgactctgt ttgccaataa
      421 caccgttaca ggagaatata ataacggcgg agccatattt gctaaagaaa actcaacgct
      481 gaatcttact gatgttattt tttccggtaa cgtcgcaggc ggctatggtg gcgcaatcta
      541 ttcttctggt actaacgata ctggtgccgt cgatttacgt gtcactaacg ccatgtttcg
      601 caataacatc gctaatgatg gcaaaggtgg cgcaatttat accattaata atgacgttta
      661 tttaagtgat gttatttttg ataacaacca ggcatataca tcaacaagtt acagtgatgg
      721 cgatggcggg gcaatcgatg ttaccgataa taatagcgac agcaagcatc cttcaggtta
      781 tacgatagta aataacactg cctttacaaa taacactgcc gaaggttatg gcggggcgat
      841 atataccaat agcgtgacgg ctccctatct tattgatatt tctgttgatg acagctacag
      901 ccagaacgga ggcgtgttag tcgatgagaa caatagcgca gcaggctatg gagatggtcc
      961 ttcctctgcg gcgggtggct ttatgtatct cggcttaagt gaagttacct ttgatattgc
     1021 cgacggaaaa acgctggtta ttggcaatac agagaatgac ggagctgttg actctattgc
     1081 tggtaccggg ttaatcacca aaacaggttc cggcgatctg gtacttaatg cagataacaa
     1141 tgactttact ggtgagatgc agattgaaaa cggtgaagtt accctgggcc gcagcaactc
     1201 cctgatgaat gtcggcgata cgcattgcca ggacgatccg caagactgct acggtctgac
     1261 gatagggagt attgatcagt atcagaatca ggctgagcta aacgttggct cgacccaaca
     1321 aacttttgtg cacgcattga cgggctttca gaatggcact ttaaatatcg atgctggtgg
     1381 caacgttact gttaatcagg gcagttttgc tggcatcatc gaaggtgctg gtcagctcac
     1441 cattgcgcaa aacggcagct acgtgctggc aggggcgcag tcgatggcgc taaccggcga
     1501 tatagtcgtt gatgatggtg cggtgctttc gctggaaggc gacgcggcag atcttaccgc
     1561 tctccaggac gatccgcagt cgatcgtgtt aaacggcggt gtgctcgatc tctctgattt
     1621 ctccacctgg cagagcggca catcatacaa cgatggcctt gaagtcagtg gcagcagcgg
     1681 aacggttatc ggcagtcagg atgtggtaga tcttgcaggt ggcgacaatt tgcatatcgg
     1741 cggcgacggg aaagatggcg tctacgtggt ggtcgatgcg agcgacgggc aggtaagtct
     1801 ggcaaacaat aatagttatt tgggcacaac acaaatcgcc tccggtacgc tgatggtgag
     1861 cgacaactcg cagcttggag atacccacta taaccgccag gttatcttta ccgataagca
     1921 acaagaaagc gtgatggaga ttacctccga cgttgacacg cgttcagatg cggcaggcca
     1981 cggacgtgat attgaaatgc gcgccgacgg tgaagtggca gttgatgcgg gggtagacac
     2041 gcagtggggc gcactgatgg ctgacagcag cgggcagcat caggatgagg gtagcacatt
     2101 gactaaaacg ggggctggta cactggagct gaccgccagc ggtacaacgc agtcggcggt
     2161 acgtgtcgaa gaaggcaccc tgaaaggtga tgttgctgat atccttcctt atgcttcgtc
     2221 actgtgggtt ggtgatgggg caacgttcgt tactggcgcg gatcaggata ttcagtcaat
     2281 tgatgctatt tccagcggca ctatcgacat cagcgatggt acggttttgc gcctgaccgg
     2341 gcaggatact tccgtcgccc ttaatgcctc actatttaac ggcgatggga cgctggtgaa
     2401 tgccaccgat ggtgtgacgt tgacaggtga gcttaatacc aaccttgaaa ctgacagcct
     2461 gacttatctt tccaacgtga cggttaatgg caatctgacc aatacgtccg gtgcggttag
     2521 cctgcaaaat ggcgtcgctg gcgatacgct gacggtaaac ggtgattata ccggcggcgg
     2581 tacgctactg ctcgatagcg aattaaacgg cgatgactcg gtaagcgatc aattggtgat
     2641 gaacggtaat actgctggca acacaactgt ggtggttaac tccattacag ggattggtga
     2701 gccgacatcg acaggcatta aagtggttga tttcgcagct gatcccacgc agtttcaaaa
     2761 caatgcgcag ttcagtctgg caggcagcgg ctacgtcaat atgggagcgt atgactacac
     2821 gctggtggaa gataacaacg actggtatct gcgatcgcaa gaagtaacgc cgccatcgcc
     2881 acctgatcca gacccgactc ccgatcctga tcccacgccg gatcctgatc caacacccga
     2941 cccggaacct acgcctgctt accagccggt gttgaatgcc aaagttggcg gttatctcaa
     3001 taacctgcgg gcggcaaatc aggcgtttat gatggagcga cgcgatcacg caggtggcga
     3061 tggtcagacg ctgaatttac gtgttatcgg cggagattat cattacacag cagcggggca
     3121 actggctcaa catgaagaca cttctacggt gcaacttagc ggcgatctgt ttagcgggcg
     3181 ctggggcacg gatggcgagt ggatgcttgg gattgttggt ggctacagcg ataaccaggg
     3241 cgacagccgc tcgaatatga ccggaactcg cgccgataac cagaaccacg gttatgccgt
     3301 tgggctgaca tcaagctggt ttcagcacgg taatcagaag caaggggcct ggctggatag
     3361 ctggctgcaa tacgcgtggt ttagcaatga tgtttccgaa caagaagatg gcacagatca
     3421 ttaccactcg tcggggatta tcgcctcgct ggaggcgggg tatcagtggt taccggggcg
     3481 tggtgtggtg attgaaccgc aggcgcaggt gatttatcag ggcgtgcagc aggatgattt
     3541 taccgccgct aaccgtgcgc gcgtgtcaca atcgcagggt gatgatattc agacgcggct
     3601 gggtttacac agcgaatggc gtaccgctgt tcatgtcata ccaacattag atctgaatta
     3661 ttatcacgat ccccattcga cggaaattga agaggatggc agcactatca gtgacgatgc
     3721 ggtgaagcaa cggggtgaaa taaaagtggg agtcacgggc aatatcagtc agcgagtgtc
     3781 cctgcgcggc agcgtggcgt ggcagaaagg gagtgatgat tttgcccaga cggcagggtt
     3841 tttgtcgatg acggtgaaat ggtaatcact gtctagtcgg cacggttgcc ggatgcggcg
     3901 taaacgcctt atccggccta cggggagcat ttgtaggcct gataagacgc ggcaagcgtc
     3961 gcatcaggca ttggcgcggc caaacatcaa cctcacttat tctgcgtgtg cagcatatag
     4021 ttcacatcca cgccggggcc gagtttaaaa gtattagtga tcgggttgta atgcagccca
     4081 gtgatatgcc gctcttttaa actggtctga tccacccagc ccagcaattc tgccggttta
     4141 ataaacttct tcacatcatg cgtgcctttg ggcaccatgc gcaaaatata ttccgcacca
     4201 accaccgcca tcagccatga cttgccgttg cggttaagtg tcgagaaaaa gacatcgccg
     4261 cctggtttca ccagttgcgc acaggctctg accactgact gcggatcggg gacgtgctcc
     4321 agcatctcca tgcaggtcac cacatcatac tgcccggcat gttttgccgc gtgctcttcc
     4381 acggtttcct gcacgtaatc cacctgaatg ccgctttcca gtgcgtgcag ttttgccacc
     4441 tgcaatggct caaagcccat atccagaccg gtcaccgtcg cgccttcgcg cgccatactc
     4501 tcggccagaa tgccgccgcc acaaccgaca tcgagcacct ttttgccaaa taaaccgcca
     4561 gcacgctcgg caatatagcc cagacgcagc gggttaatgc ggtgcagcgg tttgaactca
     4621 ccttccagat cccaccagcg ggaggcgacg gcttcaaatt tagcgatctc ttcgtggtct
     4681 acgttatggt ttaccggcga tttttcggca ttcattggca cttctactcc gtaattggca
     4741 agacaaacga gtatatcagg cattggatgt gaataaagcg tataggttta cctcaaactg
     4801 cgcggctgtg ttataatttg cgacctttga atccgggata cagtagaggg atagcggtta
     4861 gatgagcgac cttgcgagag aaattacacc ggtcaacatt gaggaagagc tgaagagctc
     4921 ctatctggat tatgcgatgt cggtcattgt tggccgtgcg ctgccagatg tccgagatgg
     4981 cctgaagccg gtacaccgtc gcgtacttta cgccatgaac gtactaggca atgactggaa
     5041 caaagcctat aaaaaatctg cccgtgtcgt tggtgacgta atcggtaaat accatcccca
     5101 tggtgactcg gcggtctatg acacgatcgt ccgcatggcg cagccattct cgctgcgtta
     5161 tatgctggta gacggtcagg gtaacttcgg ttctatcgac ggcgactctg cggcggcaat
     5221 gcgttatacg gaaatccgtc tggcgaaaat tgcccatgaa ctgatggccg atctcgaaaa
     5281 agagacggtc gatttcgttg ataactatga cggcacggaa aaaattccgg acgtcatgcc
     5341 aaccaaaatt cctaacctgc tggtgaacgg ttcttccggt atcgccgtag gtatggcaac
     5401 caacatcccg ccgcacaacc tgacggaagt catcaacggt tgtctggcgt atattgatga
     5461 tgaagacatc agcattgaag ggctgatgga acacatcccg gggccggact tcccgacggc
     5521 ggcaatcatt aacggtcgtc gcggtattga agaagcttac cgtaccggtc gcggcaaggt
     5581 gtatatccgc gctcgcgcag aagtggaagt tgacgccaaa accggtcgtg aaaccattat
     5641 cgtccacgaa attccgtatc aggtaaacaa agcgcgcctg atcgagaaga ttgcggaact
     5701 ggtaaaagaa aaacgcgtgg aaggcatcag cgcgctgcgt gacgagtctg acaaagacgg
     5761 tatgcgcatc gtgattgaag tgaaacgcga tgcggtcggt gaagttgtgc tcaacaacct
     5821 ctactcccag acccagttgc aggtttcttt cggtatcaac atggtggcat tgcaccatgg
     5881 tcagccgaag atcatgaacc tgaaagacat catcgcggcg tttgttcgtc accgccgtga
     5941 agtggtgacc cgtcgtacta ttttcgaact gcgtaaagct cgcgatcgtg ctcatatcct
     6001 tgaagcatta gccgtggcgc tggcgaacat cgacccgatc atcgaactga tccgtcatgc
     6061 gccgacgcct gcagaagcga aaactgcgct ggttgctaat ccgtggcagc tgggcaacgt
     6121 tgccgcgatg ctcgaacgtg ctggcgacga tgctgcgcgt ccggaatggc tggagccaga
     6181 gttcggcgtg cgtgatggtc tgtactacct gaccgaacag caagctcagg cgattctgga
     6241 tctgcgtttg cagaaactga ccggtcttga gcacgaaaaa ctgctcgacg aatacaaaga
     6301 gctgctggat cagatcgcgg aactgttgcg tattcttggt agcgccgatc gtctgatgga
     6361 agtgatccgt gaagagctgg agctggttcg tgaacagttc ggtgacaaac gtcgtactga
     6421 aatcaccgcc aacagcgcag acatcaacct ggaagatctg atcacccagg aagatgtggt
     6481 cgtgacgctc tctcaccagg gctacgttaa gtatcagccg ctttctgaat acgaagcgca
     6541 gcgtcgtggc gggaaaggta aatctgccgc acgtattaaa gaagaagact ttatcgaccg
     6601 actgctggtg gcgaacactc acgaccatat tctgtgcttc tccagccgtg gtcgcgtcta
     6661 ttcgatgaaa gtttatcagt tgccggaagc cactcgtggc gcgcgcggtc gtccgatcgt
     6721 caacctgctg ccgctggagc aggacgaacg tatcactgcg atcctgccag tgaccgagtt
     6781 tgaagaaggc gtgaaagtct tcatggcgac cgctaacggt accgtgaaga aaactgtcct
     6841 caccgagttc aaccgtctgc gtaccgccgg taaagtggcg atcaaactgg ttgacggcga
     6901 tgagctgatc ggcgttgacc tgaccagcgg cgaagacgaa gtaatgctgt tctccgctga
     6961 aggtaaagtg gtgcgcttta aagagtcttc tgtccgtgcg atgggctgca acaccaccgg
     7021 tgttcgcggt attcgcttag gtgaaggcga taaagtcgtc tctctgatcg tgcctcgtgg
     7081 cgatggcgca atcctcaccg caacgcaaaa cggttacggt aaacgtaccg cagtggcgga
     7141 atacccaacc aagtcgcgtg cgacgaaagg ggttatctcc atcaaggtta ccgaacgtaa
     7201 cggtttagtt gttggcgcgg tacaggtaga tgactgcgac cagatcatga tgatcaccga
     7261 tgccggtacg ctggtacgta ctcgcgtttc ggaaatcagc atcgtgggcc gtaacaccca
     7321 gggcgtgatc ctcatccgta ctgcggaaga tgaaaacgta gtgggtctgc aacgtgttgc
     7381 tgaaccggtt gacgaggaag atctggatac catcgacggc agtgccgcgg aaggggacga
     7441 tgaaatcgct ccggaagtgg acgttgacga cgagccagaa gaagaataat tttacttctt
     7501 catgccaaaa gggagctatc tcccttgttt gaattgaaaa gtccaggctg caaagtctgg
     7561 gcttttgtcg tattagggca cggtaaagtt tggctgtgcc cgtaaaaaat ggctggctat
     7621 acacaaggaa tgtggcaatg agtggtgaaa aaaaggcgaa aggctggcgg ttctatggtc
     7681 ttgtaggttt tggcgcaata gcactgcttt ccgctggcgt ctgggcgttg caatatgctg
     7741 gcagtgggcc agaaaaaacg ttgtcgccgc tggtggtgca caacaatctg caaatcgatc
     7801 tcaatgagcc ggacctcttt ctcgacagcg actctctgag ccagcttccc aaagatctcc
     7861 tcaccattcc gtttctccac gatgttctga gcgaagattt cgttttctat tatcagaatc
     7921 atgccgatcg tctgggcatt gaaggcagca ttcgtcgtat tgtctatgaa cacgatctca
     7981 cgctgaaaga taagctcttt tcgtcactct tagatcagcc cgcgcaggca gcgctgtggc
     8041 acgataaaca aggccatctt tcacattata tggtgctgat ccagcgcagt ggtttaagca
     8101 aactgctgga gccattgttg tttgccgcta ccagcgacag ccagttaagc aaaacggaaa
     8161 tcagtagcat caagataaat agtgaaactg ttcctgttta tcagttgcgc tataacggca
     8221 ataacgccct gatgttcgcg acttatcagg acaagatgct ggtgttttcc agcacggata
     8281 tgttgtttaa agatgatcag caggataccg aagccacggc gatcgcaggt gatttgttga
     8341 gcggcaaaaa acgctggcaa gcaagctttg gcctggaaga gcgtactgcc gaaaaaacgc
     8401 cagtacgcca gcgcatcgta gtcagcgcca ggtggctggg gtttggctac cagcggttaa
     8461 tgccttcttt tgctggcgta cgcttcgaaa tgggtaacga cggctggcac agttttgtgg
     8521 cgttaaatga tgaatccgcc agcgtagatg ccagtttcga ttttacgccg gtatggaaca
     8581 gtatgcctgc cggagccagc ttctgtgtgg cggtgccgta ttcacacggt attgccgaag
     8641 agatgctttc gcacatcagc caggaaaacg acaagctgaa tggggcgtta gacggtgccg
     8701 cggggctgtg ctggtatgaa gactcaaaat tgcaaacccc gctgtttgtc ggtcagtttg
     8761 atggcactgc cgaacaggcg caattgccag ggaaactgtt tacgcaaaat attggtgcgc
     8821 acgaaagcaa agcgccagaa ggtgttttgc cggtaagcca gactcagcag ggcgaagcgc
     8881 aaatctggcg tcgcgaagtg agttcccgat acggccagta tccgaaagcg caggcggcgc
     8941 aacccgatca attaatgtcg gattattttt tccgtgtgtc gctggcgatg caaaacaaaa
     9001 cgctgctttt ctccctcgat gacacgctgg ttaataacgc gctgcaaaca ctgaataaaa
     9061 cccgcccggc aatggtggat gtaataccca ctgatggcat cgttccgctc tatatcaatc
     9121 cacaaggaat agcgaaactg ctgcgtaacg aaacgttgac cagtctgccg aagaatctcg
     9181 aaccggtttt ttataacgcc gcacaaactt tattaatgcc gaagctggac gctttatctc
     9241 aacaaccgcg ttatgtcatg aagctggccc agatggaacc cggtgccgcc tggcagtggc
     9301 tacccataac ctggcagccg ctatgaggca cgggctgctg gcgctgattt gctggctgtg
     9361 ttgtgttgtt gcccatagcg aaatgctgaa tgtcgaacaa tccgggctgt ttcgcgcctg
     9421 gtttgtacgc attgcacaag aacagctccg ccaggggcca agtccacgct ggtatcagca
     9481 ggattgtgcg ggcctggtgc gatttgcggc gaacgagacg ctgaaagttc acgacagtaa
     9541 atggctaaaa agtaacggtt tatctagcca gtatttgccg ccagagatga cgctaacacc
     9601 tgaacagcgt caactggcgc aaaactggaa tcaggggaac gggaaaaccg gcccctatgt
     9661 gaccgcgatt aatttgattc agtacaacag ccagtttatt ggccaggaca taaaccaggc
     9721 gctgcctggc gatatgattt ttttcgatca gggcgatgcc cagcacttaa tggtctggat
     9781 ggggcgttac gtcatctacc acaccggaag cgccacgaaa actgacaacg gaatgcgcgc
     9841 agtcagtctg caacaactta tgacatggaa ggacacccga tggataccca acgattccaa
     9901 tcccaatttc attggcattt atcgtttaaa ttttctggcg cgatagcagc gtgcttgtcc
     9961 ctgtctcttg tgggaacagg gcttgctaat gctgatgatt cgcttccttc cagcaactat
    10021 gcgccgcctg ccgggggaac attctttttg cttgctgaca gcagttttag cagcagtgaa
    10081 gaggcgaaag tgcgactgga agcgccgggg cgtgattatc ggcgctatca gatggaagag
    10141 tacggcggcg tggacgttcg cctgtatcgt attcctgacc cgatggcatt tttgcgccag
    10201 cagaaaaacc tgcatcgcat tgtggtgcaa ccgcaatatc tgggcgacgg gctgaacaat
    10261 acgctaacct ggctgtggga taactggtac ggcaaatctc gccgcgtgat gcagcgtact
    10321 ttctcttctc agtcacggca gaatgtgact caggcgttac ccgaattaca gctcggcaat
    10381 gccattatta aaccttcccg ttatgtacag aacaaccagt tttccccgct gaaaaaatat
    10441 cccctggtga aacagttccg ttatccacta tggcaggcta aaccgttcga gccgcagcaa
    10501 ggggtaaaac tggaaggcgc atccagcaat ttcatctcgc cgcagccggg taacatttat
    10561 attcctctcg gccaacaaga gccgggactg tacctcgtcg aggcgatggt tggtgggtat
    10621 cgggcgacga cggtggtgtt tgtttccgat accgtggcgc ttagcaaagt gtcaggcaaa
    10681 gagcttctgg tgtggaccgc gggtaaaaaa cagggtgaag cgaagcccgg ctcagagatc
    10741 ttgtggactg acggtcttgg cgtgatgacc cgcggtgtga ccgatgacag cggtaccttg
    10801 cagttacaac atatatcgcc agaacgttca tacattctgg gtaaggatgc tgaaggcggc
    10861 gtttttgtct ccgagaactt cttctacgaa agcgaaatct acaacacccg cttgtatatt
    10921 tttaccgatc gcccgctata tcgcgcaggc gatcgtgtcg atgttaaagt gatcggccgc
    10981 gagttccacg atccgttgca ttcatccccc atcgtcagcg ccccggcgaa gctttcggtg
    11041 ctggacgcca acggcagtct gttgcaaacc gtcaatgtca cgctggatgc gcgcaatggc
    11101 gggcagggaa gtttccgcct gccagaaaat gccgtagccg gaggttatga gttacgtctt
    11161 gcttaccgca atcaggtcta tagcagcagt tttcgcgtgg caaactacat caagccacat
    11221 ttcgagattg gtttagctct cgccaaaaaa gagttcaaaa ctggcgaagc ggtcagcggc
    11281 aaactgcaac tgctctaccc ggatggcgag ccggtaaaaa atgcccgcgt gcagttaagt
    11341 ttgcgcgctc agcaattatc aatggtcggt aacgatttgc gttatgccgg acgtttcccc
    11401 gtgtcgctgg aaggcagcga aacggtgtcc gacgccagcg gtcatgtggc gttaaatttc
    11461 cccgccgccg ataaaccgag ccgctatttg ttaaccgtct ccgccagtga cggcgcggcg
    11521 tatcgcgtca ccaccaccaa agagatcctc attgaacgcg gtctggcgca ttactcttta
    11581 agtaccgccg cacaatacag taatagcggc gagtcggttg tgttccgtta tgccgcgctg
    11641 gaatcttcaa aacaggttcc tgttacgtat gaatggttgc gtctcgaaga ccgcacgagc
    11701 catagcggag agctaccgtc aggcggcaaa tcctttaccg tcaatttcgc taaacctggc
    11761 aactacaatc tgacattacg cgataaagac ggcttaattc tcgctgggtt aagtcatgcc
    11821 gtcagcggta agggcagcac ggcgcatact ggtacggtag atatcgtggc ggataaaacg
    11881 ctgtaccagc caggcgaaac cgcgaagatg ctgattacct ttccggagcc aattgatgaa
    11941 gcattattga cgctggaacg cgatcgcgtg gaacagcagt cgctgctttc gcatccggca
    12001 aactggctaa cgctacaacg tttaaacgat acccagtatg aagcccgggt tccagtgagc
    12061 aattcctttg cgcctaacat cactttttcg gtgctgtata cccgtaatgg tcagtacagt
    12121 tttcagaacg ccgggatcaa agttgccgtt cctcagcttg atatccgggt gaaaacggac
    12181 aaaacccatt accagcctgg tgaactggtc aatgtcgaat taacctcgtc gctgaaaggt
    12241 aaacctgttt ctgcgcagct aacggtaggc gtggtcgatg aaatgatcta cgcgctgcaa
    12301 ccagaaatcg cgccgaatat cggcaaattt ttctatccgc tggggcgtaa caatgtgcgt
    12361 accagctcca gtctgtcgtt tatcagctac gaccaggcgc tctccagcga gccggttgcg
    12421 cctggcgcaa ctaaccgcag cgagcggcga gtaaaaatgc ttgaacgtcc acggcgtgaa
    12481 gaggtggata ccgcggcatg gatgccgtca ctcacaaccg ataaacaagg caaagcgtat
    12541 ttcacgttcc tgatgcctga ttcgttaacc cgctggcgta tcaccgcgcg tgggatgaac
    12601 ggcgacgggc tggtcgggca ggggcgtgct tatctgcgtt cggaaaaaaa tctctacatg
    12661 aagtggagta tgccaacggt gtatcgcgtg ggcgacaaac cggcggcagg actgtttatc
    12721 ttcagtcagc aggataacga accggtggcg ctggtgacta aatttgcagg cgctgagatg
    12781 cgccagacgc tgacgctgca caaaggggcg aattatattt cgctgacgca gaatattcag
    12841 caatctggct tgttaagtgc agaactgcaa caaaatgggc aagtgcagga cagcattagc
    12901 acaaaactgt cttttgtgga taacagctgg cccgttgaac agcagaaaaa tgtcatgctc
    12961 ggtggtggcg ataacgcgct gatgttgccc gagcaggcga gcaatatccg gctacaaagt
    13021 agtgaaacgc cgcaggagat tttccgcaac aatcttgatg cgttagtcga tgaaccgtgg
    13081 ggtggcgtaa tcaacaccgg tagccgtctg atcccgctca gtctcgcctg gcgttcgctt
    13141 gccgatcatc aaagtgccgc cgctaacgac attcgtcaga tgattcagga taaccgtctg
    13201 cggctgatgc aactggcggg gcccggagcg cgctttacct ggtggggtga agatggcaat
    13261 ggtgacgcct tccttacggc atgggcatgg tacgccgact ggcaggccag ccaggcgatc
    13321 ggcgtaacgc aacaaccgga atactggcag catatgctcg acagctacgc ggagcaggca
    13381 gataacatgc cgttattgca tcgggcgctg gtgctggcat gggcgcagga gatgaatttg
    13441 ccgtgcaaaa cgttgttgaa agggttggat gaagctatcg cccggcgcgg aactaaaact
    13501 gaagatttct ctgaggaaga cacccgcgat atcaatgata gcctgatcct cgatacaccg
    13561 gagtctccac tggcagatgc ggtggcaaac gtcttaacca tgacgttgct gaaaaaagcg
    13621 cagttgaagt ccacggtgat gccacaggtt cagcaatatg cgtgggataa agcggcaaac
    13681 agcaatcagc cgctggcgca cacggttgtg ctgcttaata gcggtggcga cgctacccag
    13741 acggccgcta ttttaagtgg tttgaccgct gagcaatcca ctattgagcg cgcgctggcc
    13801 atgaactggc tggcgaaata tatggcgaca atgcctccag ttgttttgcc tgcgcctgcg
    13861 ggcgcatggg ctaaacataa gttaactgga gggggcgaag actggcgttg ggttggtcag
    13921 ggtgtgccgg acattctctc ttttggtgac gaattatcgc cgcaaaatgt gcaggtccgc
    13981 tggcgtgaac cggcaaaaac ggctcaacaa agtaacattc cggtgaccgt tgaacgccag
    14041 ttgtatcggc ttatccccgg tgaagaagag atgagcttta ctctgcagcc ggtgaccagc
    14101 aatgagattg acagcgatgc gctgtatctc gatgaaatta cgcttaccag cgagcaggat
    14161 gcagttctgc gctatggtca ggtggaagta ccgctcccgc cgggagccga cgttgagcgc
    14221 acaacatggg gcatttcagt caataaaccc aacgccgcga aacagcaggg gcaattgctg
    14281 gaaaaagcgc gtaatgaaat gggcgaactg gcctatatgg tgccggtgaa agaactgacg
    14341 ggaacggtca ctttccgcca tttgctgcgc ttctcgcaaa aagggcaatt cgttctgcct
    14401 cctgctcgtt atgtgcgttc ctatgcacct gcgcagcaaa gtgttgcggc agggagtgaa
    14461 tggaccggga tgcaggtgaa ataagtgaac tggcgcagaa tcgtctggct attggcgttg
    14521 gttactctgc caacacttgc ggaggagacg ccgttacaac tggtgctgcg cggtgcgcag
    14581 cacgatcaac tgtatcagct gtcgtcatca ggcgtgacca aagtctcagc attatctgac
    14641 tcgctcacca cgccgttagg gagtttgtgg aaactgtatg tttacgcctg gctggaggat
    14701 acccatcaac cggagcagcc ctaccagtgt cgcggaaact ccccggaaga ggtttattgt
    14761 tgtcaggctg gggagagcat aacgcgcgat accgcgctgg tacgttcctg tgggctctat
    14821 tttgcgccgc agcggttgca tattggcgca gatgtgtggg ggcaatactg gcaacagcgt
    14881 caggcacctg cgtggttagc gtctctgact acgctgaagc cagaaacctc ggtaacggtt
    14941 aaatcgctgc ttgattcatt agcgacgtta cccgcgcaaa acaaagctca ggaagtctta
    15001 ctggatgtgg tgctggacga ggcgaaaatc ggtgtcgcat ccatgctcgg tagtcgggta
    15061 cgggtgaaaa cctggagctg gtttgccgat gataaacagg aaatccgtca gggtggtttt
    15121 gctggctggt taaccgatgg tacaccgctg tgggttactg gcagtggcac cagcaaaacg
    15181 gtactaaccc gttatgcgac ggtgcttaat cgggttttgc cagtgccgac gcaggttgcc
    15241 agtgggcaat gtgtagaggt ggagctgttt gcccgctatc cgctgaagaa aatcacagcg
    15301 gaaaagagta cgacggcagt aaatcccggc gtacttaatg ggcgctatcg tgtgacgttt
    15361 actaatggta accacattac gtttgtcagc cacggtgaga cgaccttact gagcgaaaag
    15421 ggcaaactga aattgcagtc gcatctcgat cgtgaagagt acgttgccag agttctggat
    15481 cgcgaggcga aaagtacgcc ccctgaggca gcgaaagcca tgaccgtggc gattcgcact
    15541 tttttacagc aaaacgccaa tcgggaaggc gattgcctga ccatccccga cagcagcgcc
    15601 acgcagcgtg tttctgcttc gccagcgacc acgggggcgc gaacgatgac cgcctggacg
    15661 caggatctca tctatgcagg cgatccggtt cattatcatg gcagtcgcgc taccgaaggg
    15721 acactttcct ggcggcaagc cacggcccag gcggggcagg gagagcgtta cgaccagata
    15781 ctcgcgtttg cttatcccga caacagcctt agccgctggg gagcgccacg ctcaacctgc
    15841 cagttattac ccaaagcgaa agcctggctg gcgaaaaaaa tgccgcagtg gcggcgtata
    15901 ttacaagctg agacggggta caacgaacca gacgtgtttg cggtttgccg tttagtctca
    15961 ggtttcccct ataccgatcg gcagcagaaa cggctgttta ttcgtaactt ctttacgctt
    16021 caggatcggc tggatttaac ccatgagtat ctgcacctgg cctttgatgg ttatcccacc
    16081 gggcttgatg agaactatat cgaaacgctg acccgacaat tattaatgga ctaatgctat
    16141 gcgaaagatt tttcttccgt tgttactggt ggcgctttcg cctgtcgctc acagtgaagg
    16201 tgtgcaggaa gtcgagattg atgcaccgct ctcaggctgg catccggcag agggcgaaga
    16261 tgccagtttt tcacaatcga tcaattaccc ggcgtcgtcc gtcaacatgg cagatgatca
    16321 aaatatctca gcgcagatcc gcggcaaaat aaagaattat gctgcggcgg gtaaagttca
    16381 gcagggccgg ctggtggtca acggtgccag tatgccgcag agaattgaat ccgatggttc
    16441 atttgcacgc ccttatattt tcactgaagg cagcaacagc gtgcaggtca tcagcccgga
    16501 tgggcaaagc cgacaaaaaa tgcagtttta ctcaacgccg ggtacaggaa cgattcgtgc
    16561 acgtttacgg ctggttctct cgtgggatac ggacaatacc gacctcgacc ttcacgttgt
    16621 tacgcccgat ggcgaacacg cctggtacgg taacaccgtg ctgaaaaaca gtggtgcact
    16681 ggatatggat gtcacgacgg ggtacggacc cgagattttc gccatgcccg cgccaattca
    16741 cgggcgctat caggtgtata tcaactacta tggtgggcgc agcgaaacgg aattaaccac
    16801 cgcccaactg acgctgatca ccgatgaagg atcggtcaat gagaaacagg aaacatttat
    16861 tgtaccgatg cgtaatgctg gcgagctgac gctggtgaaa agttttgact ggtgattaat
    16921 ggggttacct tcgccgtcga tgttcaagaa aacacccgat aactttcgct atcgggtgtt
    16981 tttattgatt aattcaaccg ttcaatcacc atcgcaattc cctggccgcc gccaatgcac
    17041 agtgttgcca gccccagcgt tttatcgcgt gcctgcatgg catgtaatag tgtgaccaga
    17101 atacgagcac cactggcacc gataggatgc ccgagcgcga tggccccgcc gttgacattc
    17161 actttctcag aatcaaagcc caggtttttc ccaacggcaa ggaactgtgc agcaaatgct
    17221 tcattagcct caatgagatc aatatccgcc agttgcagcc ccgccagttg taacgctttt
    17281 tgcgtggcag gtactggccc catacccatc aatgcggggg gcacgccacc gctggcataa
    17341 cttttaatgc gagccagggg ggtaaggcct gctgccagcg ccgcagattc ttccataatc
    17401 accagagcgg cagcaccgtc gttaatacca gacgcgttcc cggcggtaac tgttcctgct
    17461 ttatcgaagg ccgggcgcaa tgcgcctaac gcttcagtcg tagaatccgc tttcgggaat
    17521 tcgtcttgac tgaagacgaa ggttttcttc cgagtgacaa catttaccgg gacgatttcg
    17581 gctgtaaaag caccggactc aattgcggct gccgctttac gctgtgaatg tagcgccagt
    17641 tcatcctgca tttctcgggt aattccgtac tctttggcca cgttctcggc ggtaatcccc
    17701 atatgataac catgggtggc gcacatcagg ccatcgcgca ggattacgtc ataaacctgt
    17761 ccgtctccaa gacgataacc agagcgtgct tttgcatcga gtaagtaggg ggctaaactc
    17821 atattttcca taccccccgc cacaatgctc tgcgcctgac ctgcctgaat ggcctgggcg
    17881 gcaagcgcca cacttttaag acccgaacca catactttat tgaccgtgaa tccgcacacc
    17941 gtttctgcca gcccgctttt taacagtgcc tgacgcgccg gattttgccc cagcccggct
    18001 tgtaacacgt tacccataat cacttcatca acgtgttgtg aatcgatttt tgcacgttca
    18061 atggcggctt taattactgt cgcccccagg tcgatggcgc tggtggaagc gagtgaaccg
    18121 ttaaaactac cgatagcagt acgtaccgca ctgacgatga cacaattttt cattttttat
    18181 tccttctgtc tgtagggttg ccgtcagaac agcgttaaac caatgacgaa aatgacgccg
    18241 gagaagagca gggcagtgat gcaatagccc atgatgtcgc ggacaccgag tccggcgatt
    18301 gccagtgctg gcagcgccca gaatggttgt gccatgttca tccattgctc gccgtaggcg
    18361 atcgccatta ccgatttacc gagatcagcg cccagcgcct gggctgcggg tatcacgaaa
    18421 ggtccctgaa taacccagtg accgccgcca gacggaacgg cgaagttaat cagtgcagaa
    18481 ctaaaaaagg tcattaccgg gaaggtgtct ttgttcgcaa cattgatgaa gaattcggta
    18541 atgagtccgc ccagaccgga atgctccatc atcagttgga tcccagcgta gaaggggaat
    18601 tgcaccagaa taccggcagt actgcgtgct gccgcgctga tagcacgcat ataagccatt
    18661 ggcgttttat gtagcagcag acccgcaatc ataaacatca ggttgacggt attgatggtg
    18721 atgttgaagc catgttcgct gaagtacatc gcaaggtaag cgataccgag tgcgccgatg
    18781 atcaacgtca gaatgcggct ttcttccagt cgctcggatg gtggggcatc tttcggtagc
    18841 tgcttttgaa aatcagcctc ttccatgagt agtttcggat cgatactcac cacgtcagac
    18901 ggttttggca tcatcatgcg ggtgataaat ggcatcacca caatcaacgc cacagtgatg
    18961 aaaatattaa aaccactgaa cagagtatcg cccaccggga tcagcccggc gatatgctca
    19021 accgggttgc ccggtgttgc agccaacaga ggcattgatc cagagaagcc gccaccccag
    19081 gtgagaaaac caatgtaggc gcaggcaatg agcaacggat aatcagaacc ggggactcgc
    19141 cgggcgactt cacgggcaaa cattgcgccg acaaccaaac caaatcccca gttgatgaca
    19201 caagcgactg aaccgaagaa agtgaccagc atgacgccct gtacgggcgt ctttgcggcg
    19261 gaggcggcag tacgcagcaa acttttcacc ggagcagagc tggcaagggc atgaccggta
    19321 acgatgataa gcgccatctg cataccaaac gccagcaagt tccagaaacc gtcaccccac
    19381 attttcacca tgctgatcgg cgtttgtggt gttaaccaaa gcgcgatcac gaatgttagc
    19441 aatgtcagca acatggcaaa gatcagtgga tcgggaagcc accggctgac aaaacgcgtc
    19501 ataaaacgcg atatgcgacc aatcataaat caccccgttg cgtattcaga tcggcggcga
    19561 cttcaaaccg agcttctgtt ttggcacgca cggtggctaa atcacacccg tcggcaattt
    19621 cggtgagcca cattttgccg tcaataaaac gaaagacagc cagttcagta accagcatat
    19681 gcaccgcatg ttgtgcagtg agtggcatgg tgcagcggcg caaaattttt gctgaaccat
    19741 ctttggcgca atgttccatg gcgatgatca ctttgcgcga cccggtcacc agatccatcg
    19801 cgccacccat accgggcacc attttcccag gcactaccca gttcgcgagg tttgcttctt
    19861 cgtctacttg caaaccgccg agcacgcagg catcaatatg accgccacgg attagcgcaa
    19921 atgacatggc gctatcaaac atggctgcac cgggtaaaac accgcacggt tgtccgccag
    19981 cgttcaccag atctggatgc gctgtcgtga ccgggcctaa accgaggaag ccgttttccg
    20041 attgcagagt gatatgaata ccctccggta aataattggc gaccattgtg ggtaaaccga
    20101 tccctaagtt aacgatgtca ccatcacgaa gctcttgcgc cacacggcgc gcaatacgtt
    20161 gtttcgcatc cattatttgc tctcctgtga aacgatgatg tggtcgataa cggcaccagg
    20221 ggtgacaata tggtcaggtt gcagctcgcc ggtttcgacc agttcatctg gctctaccag
    20281 cgtgatatca gctgcaaggg ctatcagggg gttaaagttg cgggcgctaa gttgataggt
    20341 caggttgcca agtgtgtcgc aacgatgagc gcgaattagc gccaggtcgg cgcgcagtgg
    20401 gcgttcgagc agccaggttt taccgtcgag tgtcagtgtc tgtttgcctt cctctacgac
    20461 ggtgccgaca cccgttgggg tgagaaaacc accaagtcca gctccaccac agcgaatttg
    20521 ctcgattagc gtaccttgcg gcaccagaac gacgtccatc tcaccagata tcatgcgccg
    20581 acctgtttcc gggttggtgc cgatatgtga agcaatcact ttgcggactc gaccattgac
    20641 gatgagcgga ccgatgccgg tatcaacaaa cgcggtatca ttggctatca atgtcaggtc
    20701 gcgaacacca gattccagta atgcttcaac caggcgggat ggagtgccaa tccccataaa
    20761 tccgcccacc atgatggtca tgccgtcacg aaagaagccg gtggcgtctt gtaatgtcat
    20821 caattttgtt ttcatttttt atccctcttg catacaccgt tgtgggtaca gtcaggcaat
    20881 agcaagggga gtgccagaat gagattattg gatttagtta tttaactaat tgaatatgaa
    20941 ggggtaaatt ggatgggggt ttataaggag aatgagcggc tatgcagaaa attgcgcact
    21001 gtgcaaattt ctgcatagca agttttggtg ttatacatcc gccggatcga taccgtattc
    21061 ctggagttta tacatcaatg cacggcgact gatgcccagc attaaagcag tgcgggttcg
    21121 gtttccttct tgttgttcca gcacttccat aatgatgcgt ttttcgacgc gtttaatttc
    21181 ctcttttaaa ttacgctcac cgacaggggc tgtttttacc tcgccagcat tacagtctgg
    21241 ctgacgaatc tgtggcggaa gatcctcaga aaaaatgatc gggcctgaat tcatcacgac
    21301 ggcgcgttca ataacgttgg aaagctctcg aatatttccc ggccatgacc aggcggtaag
    21361 cagtgacatt gccatcggat cgatgtcgat aatatcgcgc tgattctcac tactgaattt
    21421 ttgcaaaaag tgattagcta acagggaaat atcttcccgg cgatcgcgca gaggcggcag
    21481 tattaaatga ataacgttaa ggcgataaaa gagatcttca cggaaggtgc cttcttttac
    21541 cattgcctgc aagtcgcggt tggtggcagc aatgatgcgg atatcaactt ttatggtctg
    21601 atggccgcca atccgttcaa attcccgttc ctgtagaatg cgtagtaatt tggcttgtag
    21661 taccagcggc atttcgccaa tttcgtcgag gagcagagta ccttcgttgg ctcgttcaaa
    21721 taatccctga cgcaaggttt gtgcaccagt aaatgcacct ttttcatgac caaacagttc
    21781 actttcgagc aacgattccg gcagcgccgc gcagttgact ttaatgaacg gcccctttac
    21841 ccgccgcgaa ttgtagtgaa tcgctctggc aatcaactct ttcccggtgc cgctttcacc
    21901 gctaatcaag acgctggcct gagaaagggc aattttggcg gtgtctttgc agatgtccat
    21961 catcgccggg ctgttggtga gaatgtgccc ccattgccag ctggtgctca gtgcctggtg
    22021 cagatgacgg atctcttttt tcattgactg gagttgtaaa gcgcgctgaa cgattaaatt
    22081 caactcatcg agatcaaacg gtttaataac atagtcgaag gctccgcagc gtagcgcttc
    22141 gacggcggtt tccacttccg cataggccgt catcagaata acgggtgtcc gggtctcatg
    22201 gctgcgcatc tcctttagtg ccttgatgcc gtccatctct ggcatgcgga tatccatcaa
    22261 caccacatca gggtgaatat cggcaaacag gtgtaatgct gtgcgtccgt tgttcgcaca
    22321 atgtgtttcg aatccttgta gtgcaaaagc ggtgctcagc atacggcgaa cattatcttc
    22381 atcatccaca ataaggatgc gattaatagc agtcatacag tctgatttcc ctgcgggttg
    22441 atcggtaaaa taagcgtgaa ggttgcgccg tagcccggca aactggcgac gcgaatatca
    22501 ccctgatggg cattaatgat gcgttgactt aacgccagac caagcccggt tcctgaggct
    22561 ttggtggtga aaaagggatc gaagatcttt ttttgcagcg agagatcaat gccacagccg
    22621 ttgtcctcta tcgaaatggc ctgttgtgag tcgctgtatt gccaggtttg aatgcgaatt
    22681 ttccctcgtg cgctgatagc ctggacggca ttgatcagga tattcagtag tacctgtttg
    22741 agcagttcac gatcggcgtt aatcgggctt aattcattat ccagttcgct tatgaagtcg
    22801 acccgcgctt gtacgccggc ggtttgtacc agtaccagag tttcttcaac caatgcattg
    22861 aggctgactt gttgccattg actgtggcgt ggacgtgaaa attcgagcaa ttgctgaata
    22921 actttgttaa ttgaatcgat ttctttgagt actacggaca gatattcctg atgtattggg
    22981 tcactggttt gttggcgcaa gatctgtaca taaccacgaa tagccgttaa cggattacgt
    23041 acttcatgcg cgacgccagc catcagctca cccagtgtgg cgaggcgttc tgcttgcgcc
    23101 atgcggcgct gggtttcttt gcgggcagtt aaatcagaga aaatcaccaa agcacctatc
    23161 atttcaccgt gcgtgttatg aatacgactg gtagtgacac tgagttcaat ggtgcggtca
    23221 cgacctggaa aactgatctc cagcgccaca tgttcggtgc catgttccag cgtatccagt
    23281 actggactgt agaactgagt attgtcgaac aacatggagt aaggctgccc taccagttca
    23341 tggcgttgat agccagtgat aacttctgct gccgggttca tggtggttac atcaccctgg
    23401 cggtcaatgg caatgacgcc atcggcagcg ttttcaataa tcagatcgtt aagtgtccgc
    23461 gtttcacgca gtgcctgggc gaggttatta acactctgac tgatttgccc catttcaccg
    23521 ggcaattgtg gtaatcgagt gggaatattt tgtgccagag tcgagaggcc atcggtgatg
    23581 atatcaatat tggcgctcag gcgacgggag aaaaggacaa tcaacagcag gcttatcagc
    23641 aaaccggcgg tgagcacaat gataatcctc acatccattt tccaggcctg gcggcgaata
    23701 tcttcggtta attcattggc ccagatatag ccgaggattt caccattacg ctcaatgggg
    23761 atcattgaat tcaaaatatc gccgcgcacc tgcctgcctg aataaaccaa aggggtattt
    23821 gtacgcatga cttcgcgacc agggtgatct gcggcaatgg taacgccgac attattctga
    23881 tatagcgctg aaggcgcgta ggtgattatc gcatccagcg ttttgttgta ataaccagcg
    23941 ccgatgccag ggaaggcgtg agtgatattt tcggtaatgg gggcaagttc tgcatttaat
    24001 gcgcggatac gctcctcacg cggtaagtcg atgtagagat cgtagcgatt gcctagcgcc
    24061 tgattaagca ggttgaccac ggcagaaagt tttttctctt tttcagataa gactgctgaa
    24121 cgtccttccg tttctacgat ataaccaata gtaagcgttg ggacaatgac catcaggatt
    24181 gccatcagga tcatttgatt gcgtaagcgg cgtggataaa tccacttcat atgatgcatg
    24241 ctgaaatcca ctagtcttgt ccggtatatg acgattatca gaggttaagg tgatgatttc
    24301 tcggcggtgt atcatattcc agagaagaga gaacattgcg gtaacacgct tttaccgcta
    24361 ccttaaccac actccatcgg tcacctgagg cggagcttcg cccctttgaa ataccttgct
    24421 tcttttcgta caaccctgaa agcctcgcgc tacatgttca gagcattggc gttagtgctc
    24481 tggctgttga ttgctttttc atccgttttt tacatcgtta atgcgttaca tcagcgagaa
    24541 tcggaaattc gtcaggaatt taatctgagt tccgatcagg ctcagcgctt tattcaacgc
    24601 acctctgatg tgatgaaaga gctgaagtac atcgccgaaa atcgcttatc ggcagagaac
    24661 ggtgtgcttt ccccgcgtgg acgagaaacg caggcggatg tgcctgcgtt tgaaccgctg
    24721 tttgccgact ccgattgttc cgcgatgagt aacacctggc gaggttctct ggagtcattg
    24781 gcgtggttta tgcgctactg gcgcgataat ttttctgcgg cttacgatct caaccgggta
    24841 tttttaatcg gcagtgataa cctctgcatg gccaatttcg gtctgcgtga tatgccagtg
    24901 gaacgcgata ccgcgttgaa agctttgcat gaacgcatca ataaatatcg aaatgcacca
    24961 caagatgata gcggcagtaa cctctactgg atcagcgaag gtccgcgccc tggcgtcggg
    25021 tatttttacg cgttgacgcc agtttatctg gcgaaccggt tgcaggcgct tttgggtgtc
    25081 gagcagacca tccggatgga aaactttttc ttaccgggta cgttgccgat gggggttacc
    25141 attcttgatg aaaatggtca taccctgatt tcgcttaccg gaccagaaag taaaattaag
    25201 ggcgatcctc gctggatgca ggaacgctcc tggtttggct atacggaagg gttccgggag
    25261 ctggtgctga agaaaaatct gccaccctca tcgctaagca tcgtgtattc ggtgccggtt
    25321 gataaggtgc tggaacgcat tcgcatgttg atccttaacg caattttgct gaatgtgctt
    25381 gccggagctg cattgtttac tctcgcacgg atgtacgagc gacgtatttt cattccggcg
    25441 gaaagcgacg ccctgcgact ggaagaacat gagcagttca atcgcaagat tgtcgcctcc
    25501 gcgccagtgg gtatctgcat tttgcgtacc gctgatggcg tcaatatttt aagtaacgaa
    25561 ctggcgcata cctatctcaa tatgcttacg catgaggacc gccaacgact gacgcaaatt
    25621 atctgtgggc agcaggtcaa ttttgttgat gtcctgacca gcaacaatac caatctgcaa
    25681 atcagcttcg tccattcgcg ctatcgtaat gaaaacgtgg ccatttgtgt gctggtggat
    25741 gtttcttcgc gcgtgaagat ggaagagtcg ttgcaggaga tggcacaagc agcggaacag
    25801 gcgagccagt caaaatcgat gttccttgcc accgtcagtc atgagctgcg aacgccgctg
    25861 tatggcatta tcggtaacct ggatctgttg caaaccaaag agttaccgaa aggcgtcgat
    25921 cggctggtga cggcaatgaa caactcttcc agcctgttgt tgaaaattat cagcgatatt
    25981 ctcgatttct cgaagattga atcggaacag ttgaagatcg aaccgcgtga gttttcaccg
    26041 cgtgaagtga tgaaccacat caccgccaac tatttaccgc tggtggtacg caagcagtta
    26101 ggcttgtact gctttattga accggatgtg ccagtggcct taaatggcga cccgatgcgt
    26161 ttacagcagg tcatctccaa cctgttgagt aacgccataa aattcaccga taccggctgt
    26221 atagttttgc atgttcgcgc ggatggcgat tatctctcta tccgtgttcg cgataccggc
    26281 gtggggatac cggcgaaaga agtggtgcgc ttgtttgatc ccttcttcca ggtcggaacg
    26341 ggcgtacagc gtaatttcca ggggaccggt ctgggtctgg cgatttgtga aaaactgatc
    26401 agcatgatgg acggcgatat ctcggtagat tcagaaccgg gaatgggcag ccagtttacc
    26461 gtgcgtattc cgttgtacgg cgctcagtac ccgcagaaaa aaggcgtgga agggttgagt
    26521 ggtaaacgct gctggctggc ggtccgcaat gcgtcgctct gtcagttcct ggaaaccagt
    26581 ttgcagcgca gcggcatcgt cgttacaaca tacgaagggc aggaaccgac tcccgaagat
    26641 gtgttgatca ctgacgaggt agtgagtaaa aaatggcagg gcagagcggt agtgaccttc
    26701 tgtcgtcgcc atattggtat tccgctggag aaagcgccag gggagtgggt acacagtgtg
    26761 gctgctccgc atgagctacc ggcattgttg gcgcgtattt atttgatcga gatggagagc
    26821 gacgatcctg ctaacgctct gccgtcaacg gacaaagcgg tcagcgataa tgacgatatg
    26881 atgattcttg tcgtggatga tcatccgatt aaccggcgtt tgctggcaga tcagttggga
    26941 tcgttgggct atcaatgtaa aaccgcgaat gatggcgtcg atgcgcttaa tgtacttagc
    27001 aagaatcata ttgatatcgt gcttagcgac gtcaacatgc caaatatgga tggttaccgc
    27061 ttgacgcaac gcattcgtca gttgggactg acgttgccgg taatcggagt aactgctaat
    27121 gcgttggctg aagagaagca gcggtgtctg gagtccggta tggacagctg cctgtcgaag
    27181 ccggtaacgc tggatgtgat aaaacagacg ctgacgttat atgccgagag ggtcaggaaa
    27241 tcgcgggatt cgtaggacgg ataaggcgtt tacgccgcat ccggcattca gtgcaaatgc
    27301 cagatgcgac gctgacgcgt cttatctggc ctactttaat gtaatttgtt gaaataatgg
    27361 gaatcgtagg ccggataagg cgtttacgcc gcatccggca atcggtgcaa atgccagata
    27421 agacactaac gcgtcttatc tggcctacag gtgattagtc tttatctgcc ggacttaagg
    27481 tcactgaaga gagataattc agcagggcga tatcgttctc gacacccagc ttcatcatcg
    27541 cagatttctt ctggctactg atggttttaa tactgcggtt cagcttttta gcgatctcgg
    27601 tcaccaggaa gccttccgca aacaggcgca gaacttcact ctcttttggc gagagacgct
    27661 tgtcaccgta accaccagca ctgatttttt ccaacaggcg agaaacgctt tccggggtaa
    27721 atttcttccc tttctgcagc gcggcgagag ctttcggcag atcggtcggt gcaccttgtt
    27781 tcagcacgat cccttcgata tccagatcca ataccgcact aagaatcgcc gggttgttgt
    27841 tcatagtcag aacaatgatc gacaggcttg ggaaatggcg cttgatgtac ttgattaagg
    27901 taatgccatc gccgtactta tcgccaggca tggagagatc ggtaatcaac acatgcgcat
    27961 ccagtttcgg caggttgttg atcagtgctg tagagtcttc aaattcgccg acaacattca
    28021 cccactcaat ttgctcaagt gatttgcgaa taccgaacaa gactatcgga tggtcatcgg
    28081 caataattac gttcatattg ttcatgtaat aggctacctt gctacagcaa gctcttgaca
    28141 taactgtcaa tgtcgctgat gtatttttct attcctggaa catccttctc acgaatcaga
    28201 tgttccagcg tttcacataa ctgcttgccg ggtaccagat ttagcatggc aaatacgcct
    28261 ttaagacgat gagccgtttg ggctaacgca gcaaagtcac tggttgctgc ttcagtatac
    28321 agcctcttaa catcatccgg tactgtgtct acaaagagcg cataatagcc gctggcatgg
    28381 agttgcgcat tttcatctcc gcccagaggc gattctgtca cctcttcctg cgccagttgc
    28441 acttcaatta attgtaagac cgcttcctgc atagcgttgc tcatattgaa gttgacgcac
    28501 aattgaccag gcccaatttc ccgtacgcca gactcatcat cgcttaaaag caagccagag
    28561 gcagtaagat tagacggatt atccgttaaa aagatatcat aatcttgact aattaatctt
    28621 tcatcgggtg tgatacaggt tgcaccccaa ttttctaact ggcgagtgac aatattccga
    28681 atttctgccg aagtaacatc caccattacg cagacatcat ccagtaaacg ctcttcttcc
    28741 tcttcaactt ccgggtcagc tgcgagcatt ttgatatgca cagagtagcg tgtaccaagc
    28801 ccatcccgcg ttttgatgtt taaatgaccg cccagtttac gtgccagttg atcgctcagc
    28861 cagaatgcca gcgggtccgc cttgccatag cgatcgtttt gggtctggtt gataaacggg
    28921 aagtgcaaat tatccatttc atgaatactt acgccttctc ccgtgtccag aatgcggaac
    28981 gtcaggcggt cttcggagga ctcatcctga tcaacctcaa gggtgatttt tcccaattgc
    29041 gttgaggtca cggcatattg catcagtagc agcaaaatac gtcgtaaggc atcgcgatcg
    29101 ccgcggcgca tatcgtgtgc tttcagatga ttgttaatca gcagttgcag acctttacgc
    29161 ttgatggcag gcaacactga aggcacaact tcatcaatta aatcctgcac ggagaacagc
    29221 accgtctcac ttttccagct atcatccgca agcatgttcg ctaactgtat ttcatcaacc
    29281 agccgcacca gcacatctgc ctgattcgcc agttgtttgc tttccggggc gttgagttta
    29341 gccgcgctct ccgccaggga ctgtgcgggt tctttcagcg catcgccaat gtttttcata
    29401 aagatcatcc gcccctgctg gtttttctca tacagacgct gcgcctgctt gagtttcttg
    29461 tttaccagca cttcgcgatc ctgatcgcga ataatgaaaa tttgtgtgcg cggcgcgacc
    29521 tggctgcgga acatgcggat ctcatacagc tcgttattga tcgtcgcctg aataatcccc
    29581 tgatgctgtt ccgccatggt ggtgatgttt tgcagattca aatgcggcag caaatgatcg
    29641 gcaattttgt tacttatgac agtgcggttc gattcctgat cgtgaaccag caggccgagc
    29701 ggcagcagtg agactatctc ttcattgatt gcccgtaaaa tgcgcaattc gttattgacc
    29761 gccgtgctgg ggacgttttc tgtactgcgg ctggagaaat ggcggaatgt ggtatagcca
    29821 aataacgcca gcgccagcaa accgatgttc agcagcagtg gcagcagaat gttttgcaac
    29881 gtatccagca ataaggtgcc ataaggaacc tgccagacca ggcgcatatc ggtagagttg
    29941 agtgccgagg agatttcaat cttcgtactg ttaaagtgga tactgacgct atccgtccct
    30001 tctttctcat tatcattgtt tcccgttgcc gtcgcgtctg gctcaaggcg gaaactgtcc
    30061 agcggcatac ccggtgggat caaatcatta atcggcagat caaaagccac gaccgttgcc
    30121 agatgtcctg gctggttaaa ggtagtacgc aatgtaaagt aatgaccgtt ctgccaggcc
    30181 aggcggcgca tgttagaaaa gctttcgcgt tcatcgaggg cgttggcctg ttgcaacatc
    30241 tctgcacgac gtgaatcaac aatgtcgctg acggtcgatt ctttaaatcc ggaggtgaga
    30301 tctttaaggg gtagggttga gatcagcacc agactgttat cctgaccatt caggtaatac
    30361 atcgaccacg gtacattttc tgcgccccac aatgtatcca gataagtgga catccgctga
    30421 gtcatctcaa gcgttgagtt gtcgtgagag ccaaagatta acgcttccgt tttgcggcgt
    30481 ggtttctcca gatagtagac atcctgtttc aggcgcgtct cttgtaaacc ttcgccggag
    30541 gagggggagg tcgtcgcggc aatgttgtcg tagatctgcc aggtcacgta acgccagtta
    30601 tcgacgcgct tttggatagc atgggtaatg tcgacaatct ggtaactttt atctttcagc
    30661 caggcgttaa cggcgctttg taccattaca cccatcgtca ccagtaacac aatgatcaac
    30721 agtaaaaaga agcgggtaat gctccccggt aggagtgaaa agcgggtcgt ggccgttgtc
    30781 tctttctgac gcattcgtgt ttatgacctg ttaaaacttc gcgaagtgat agggcagtat
    30841 aaagggtaca gtgtgaaatt ccagactctt acctgattga tgattctcta ttctcccgtg
    30901 atatttatca tcctgcattg ggggaaatag atgtacaagc gccattttgc tgtacaaata
    30961 acctacaaaa agcccaacga aaataattgc aaataaacaa agattgctgg aaattatgct
    31021 gatgttaatt atttgtgaaa tagttaacaa gcgttatagt ttttatgtgg tagcacagaa
    31081 taatgaaaag tgtgtaaaga agggtaaaaa aaaccgaatg cgaggcatcc ggttgaaata
    31141 ggggtaaaca gacattcaga aatgaatgac ggtaataaat aaagttaatg atgatagcgg
    31201 gagttattct agttgcgagt gaagg
//
LOCUS       DAPHKZ010000048        30910 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.048, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000048 DAPHKZ010000000
VERSION     DAPHKZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30910
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.048"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(6..803)
                     /gene="rfaP"
                     /locus_tag="RH288_002267"
     CDS             complement(6..803)
                     /gene="rfaP"
                     /locus_tag="RH288_002267"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HDV4031315.1"
                     /translation="MVELKEPLATLWRGKDAFAEVKKLNGEVFRELETRRTLRFELSG
                     KSYFLKWHKGTTLKEIIKNLLSLRMPVLGADREWHAIHRLSDVGVDTMKGIGFGEKGL
                     NPLTRASFIITEDLTPTISLEDYCADWAVNPPDIRVKRMLIARVATMVRKMHTAGINH
                     RDCYICHFLLHLPFTGREDELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGL
                     TQRDIWRFMKVYFGMPLRKILSLEQNLLNMASVKAERIKERTQRKGL"
     gene            complement(796..1920)
                     /gene="rfaG"
                     /locus_tag="RH288_002268"
     CDS             complement(796..1920)
                     /gene="rfaG"
                     /locus_tag="RH288_002268"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide glucosyltransferase I"
                     /protein_id="HDV4031316.1"
                     /translation="MIVAFCLYKYFPFGGLQRDFMRIASTVAARGHHVRVYTQSWEGD
                     CPKAFELIQVPVKSHTNHGRNAEYYAWVQNHLKEHPADRVVGFNKMPGLDVYFAADVC
                     YAEKVAQEKGFLYRLTSRYRHYAAFERATFEQGKSTKLMMLTDKQIADFQKHYQTEPE
                     RFQILPPGIYPDRKYSEQIPNSREIYRQKNGIKEQQNLLLQVGSDFGRKGVDRSIEAL
                     ASLPESLRHNTLLFVVGQDKPRKFEALAEKLGVRSNVHFFSGRNDVSELMAAADLLLH
                     PAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIADANCGTVIAEPFSQEQLNEVLRKA
                     LTQSPLRMAWAENARHYADTQDLYSLPEKAADIITGGLDG"
     gene            complement(1917..2987)
                     /gene="rfaQ"
                     /locus_tag="RH288_002269"
     CDS             complement(1917..2987)
                     /gene="rfaQ"
                     /locus_tag="RH288_002269"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HDV4031317.1"
                     /translation="MEKPFRKILVIKMRYHGDMLLTTPVISTLKQNYPDAKIDMLLYQ
                     DTIPILSENPEINALYGISNKGAGTFDKIKNVLSLIKTLRANNYDLVINLTDQWMVAL
                     LVRCLPARMKISQLYGHRQHGIWKKSFTHLAPIHGTHIVERNLSVLEPLGITDFYTDT
                     TMSYAEDCWKKMRRELDALGVKDHYVVIQPTARQIFKCWDNDKFSKVIDALQQRGYQV
                     VLTCGPSADDLACVDEIARGCETKPITGLAGKTRFPELGALIDHAVLFIGVDSAPGHI
                     AAAVKTPVISLFGATDHVFWRPWTENIIQFWAGNYQKMPTRHELDRNKKYLSVIPAED
                     VIAATEKLLPEDAPSADRNAQL"
     gene            3393..4670
                     /gene="waaA"
                     /locus_tag="RH288_002270"
     CDS             3393..4670
                     /gene="waaA"
                     /locus_tag="RH288_002270"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HDV4031318.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRH
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQ
                     HVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
                     AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLAKEVSSLLTDADYRS
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            4678..5157
                     /gene="coaD"
                     /locus_tag="RH288_002271"
     CDS             4678..5157
                     /gene="coaD"
                     /locus_tag="RH288_002271"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDV4031319.1"
                     /translation="MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKP
                     MFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQL
                     AHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA"
     gene            complement(5196..6005)
                     /gene="mutM"
                     /locus_tag="RH288_002272"
     CDS             complement(5196..6005)
                     /gene="mutM"
                     /locus_tag="RH288_002272"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HDV4031320.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRL
                     SDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKV
                     LRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK"
     gene            complement(6103..6270)
                     /gene="rpmG"
                     /locus_tag="RH288_002273"
     CDS             complement(6103..6270)
                     /gene="rpmG"
                     /locus_tag="RH288_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDV4031321.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            complement(6291..6527)
                     /gene="rpmB"
                     /locus_tag="RH288_002274"
     CDS             complement(6291..6527)
                     /gene="rpmB"
                     /locus_tag="RH288_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDV4031322.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY"
     gene            complement(6744..7412)
                     /gene="radC"
                     /locus_tag="RH288_002275"
     CDS             complement(6744..7412)
                     /gene="radC"
                     /locus_tag="RH288_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418095.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDV4031323.1"
                     /translation="MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTL
                     AKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLL
                     SPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHRRLFSGTLNHVEVHPREIIREAI
                     KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAE
                     RGWI"
     gene            7584..8804
                     /gene="coaBC"
                     /locus_tag="RH288_002276"
     CDS             7584..8804
                     /gene="coaBC"
                     /locus_tag="RH288_002276"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDV4031324.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRTAATQHNLEVLASRGLLIWGPDSGSQACGD
                     IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAA
                     VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNV
                     EEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            8782..9240
                     /gene="dut"
                     /locus_tag="RH288_002277"
     CDS             8782..9240
                     /gene="dut"
                     /locus_tag="RH288_002277"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDV4031325.1"
                     /translation="MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELA
                     PGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVW
                     NRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ"
     gene            9347..9943
                     /gene="slmA"
                     /locus_tag="RH288_002278"
     CDS             9347..9943
                     /gene="slmA"
                     /locus_tag="RH288_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HDV4031326.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
                     QILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(9980..10621)
                     /gene="pyrE"
                     /locus_tag="RH288_002279"
     CDS             complement(9980..10621)
                     /gene="pyrE"
                     /locus_tag="RH288_002279"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDV4031327.1"
                     /translation="MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEA
                     KDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
                     RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV"
     gene            complement(10687..11403)
                     /gene="rph"
                     /locus_tag="RH288_002280"
     CDS             complement(10687..11403)
                     /gene="rph"
                     /locus_tag="RH288_002280"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDV4031328.1"
                     /translation="MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKALGEFTITLDCDVLQADGGTRTASITGACVALVDALQKLVENGKLKTNPMKGMVA
                     AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLL
                     ALARGGIESIVATQKAALAN"
     gene            11530..12393
                     /locus_tag="RH288_002281"
     CDS             11530..12393
                     /locus_tag="RH288_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDV4031329.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRL
                     EGVTAEVVKVRSHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            12614..13438
                     /gene="dinD"
                     /locus_tag="RH288_002282"
     CDS             12614..13438
                     /gene="dinD"
                     /locus_tag="RH288_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
                     /protein_id="HDV4031330.1"
                     /translation="MNEHHQPFEEIKLINANGAEQWSARQLGKLLGYSEYRHFIPVLT
                     RAKEACENSGHTIDDHFEEILDMVKIGSNAKRALKDIVLSRYACYLVVQNGDPAKPVI
                     AAGQTYFAIQTRRQELADDEAFKQLREDEKRLFLRNELKEHNKQLVEAAQQAGVATAT
                     DFAIFQNHGYQGLYGGLDQKAIHQRKGLKKNQKILDHMGSTELAANLFRATQTEEKLK
                     RDGVNSKQQANTTHFDVGRKVRQTIQELGGTMPEELPTPQVSIKQLENSVKITEKK"
     gene            13729..14346
                     /locus_tag="RH288_002283"
     CDS             13729..14346
                     /locus_tag="RH288_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HDV4031331.1"
                     /translation="MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSI
                     IGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
                     IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH"
     gene            complement(14343..16025)
                     /gene="ligB"
                     /locus_tag="RH288_002284"
     CDS             complement(14343..16025)
                     /gene="ligB"
                     /locus_tag="RH288_002284"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418104.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
                     /protein_id="HDV4031332.1"
                     /translation="MKVWMAILIGILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQW
                     DDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRK
                     MVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSL
                     ISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSL
                     GVFVWAWPDGPQLMSDRLKELATAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVT
                     DGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLA
                     PVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTP
                     PENRFNSLTCYFASDVCQEQFISRLVWLGAKQVLGLDGIGEAGWRALHQTHRFEHIFS
                     WLLLTPEQLQNTPGIAKSKSAQLWHQFNLARKQPFTRWVMAMGIPLTRAALNASDERS
                     WSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP"
     gene            16283..16906
                     /gene="gmk"
                     /locus_tag="RH288_002285"
     CDS             16283..16906
                     /gene="gmk"
                     /locus_tag="RH288_002285"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDV4031333.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQP
                     RPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLD
                     IDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            16961..17236
                     /gene="rpoZ"
                     /locus_tag="RH288_002286"
     CDS             16961..17236
                     /gene="rpoZ"
                     /locus_tag="RH288_002286"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDV4031334.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            17255..19363
                     /gene="spoT"
                     /locus_tag="RH288_002287"
     CDS             17255..19363
                     /gene="spoT"
                     /locus_tag="RH288_002287"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HDV4031335.1"
                     /translation="MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGV
                     LITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQE
                     FITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLA
                     NIMRKIRVMPDVIKVTRNRN"
     gene            19370..20059
                     /gene="trmH"
                     /locus_tag="RH288_002288"
     CDS             19370..20059
                     /gene="trmH"
                     /locus_tag="RH288_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HDV4031336.1"
                     /translation="MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA
                     VDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD
                     ADWWATMQAAG"
     gene            20065..22146
                     /gene="recG"
                     /locus_tag="RH288_002289"
     CDS             20065..22146
                     /gene="recG"
                     /locus_tag="RH288_002289"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDV4031337.1"
                     /translation="MKGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFSAA
                     MKNSLAAGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQH
                     PAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKPTGAQARV
                     VAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFAPLGIEVGWLAGKQKGKARLAQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRTDIIDRVHHACITEGRQAYWVCTLIEESELLEAQAAEATW
                     EELKLALPELNVGLVHGRMKPAEKQAVIASFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIER
                     WMPETERYSNA"
     gene            complement(22315..23520)
                     /gene="gltS"
                     /locus_tag="RH288_002290"
     CDS             complement(22315..23520)
                     /gene="gltS"
                     /locus_tag="RH288_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDV4031338.1"
                     /translation="MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLL
                     VALALLVLKKSMGWEVNFDMSLRDPLMLAFFATIGLNANIASLRAGGRVVGIFLIVVV
                     GLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTAFELPTFVCVLFVGVILSNGLSIMGFYRVFERAVS
                     VLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAG"
     gene            23800..25191
                     /gene="xanP"
                     /locus_tag="RH288_002291"
     CDS             23800..25191
                     /gene="xanP"
                     /locus_tag="RH288_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HDV4031339.1"
                     /translation="MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNP
                     YLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGIT
                     AIVLNLIFPPEKQ"
     gene            25312..27021
                     /locus_tag="RH288_002292"
     CDS             25312..27021
                     /locus_tag="RH288_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDV4031340.1"
                     /translation="MKFIGKLLLYILIALLVAIAGLYFLLQTRWGAEHISAWVSENSD
                     YHLAFGAMDHRFSAPSHIVLENVTFGRDGQPATLVAKSVDIALSSRQLTEPRHVDTIL
                     LENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPKAGKVL
                     GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADG
                     SWQVENLRMADIRLQSEKSLTDFFAPLRSVPSLQIGRLEVIDARLQGPDWAVTDLDLS
                     LRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINTEFSPQGVALRQFTSRWEGG
                     MVRTSGNWLRDGKTLILDDAAIAGLEYTLPKNWQQLWMETTPGWLNSLQLKRFSASRN
                     LIIDIDPDFPWQLTALDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLA
                     LTANSSTVNISELSAFTEKGILEATASVSQTPQRQTHISLNGRGVPVNILQQWGWPEL
                     PLTGDGNIQLTASGDIQANVPLKPTVSGQLHAVNAAKQQVTQTMNAGIVSSGEVTSTE
                     PVR"
     gene            complement(27074..29392)
                     /gene="yicI"
                     /locus_tag="RH288_002293"
     CDS             complement(27074..29392)
                     /gene="yicI"
                     /locus_tag="RH288_002293"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HDV4031341.1"
                     /translation="MKISDGNWLIQPGLNLIHPLQVFEVEQQDNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAE
                     FKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSF
                     EVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRR
                     LKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     DACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLK
                     CRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAG
                     DVQFYLPEGRWTHLWHNDELDGSRWHKQQHGFLSLPVYVRDNTLLALDNNDQRPDYVW
                     HEGTAFHLFNLQDGHEAVCEVPAADGSVIFTLKAARTGNTITVTGAGEAKNWTLCLRN
                     VVKVNGLQDGSQAESEQGLVVKPQGNALTITL"
     gene            complement(29402..30784)
                     /locus_tag="RH288_002294"
     CDS             complement(29402..30784)
                     /locus_tag="RH288_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418114.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HDV4031342.1"
                     /translation="MKSEVLSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSMNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVNLIGGDNKPLGFQGGIAVLSVVAFMMLAFCFFTTKERVEAPPTTTSMR
                     EDLRDIWQNDQWRIVGLLTIFNILAVCVRGGAMMYYVTWILGTPEVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVTIFWWTNALLAVISLAMFFVPMQASITMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLAFGGALIGWMLAYGGYDA
                     AEKAQNSATISIIIALFTIVPAICYLLSAIIAKRYYSLTTHNLKTVMEQLAQGKRRCQ
                     QQFTSQEVQN"
BASE COUNT         7676 a         8246 c         7648 g         7340 t
ORIGIN      
        1 tatttttata atcctttgcg ttgtgttcgc tctttaatac gctcggcctt aacgcttgcc
       61 atgttcaata aattctgttc aagagacaat attttgcgta aaggcatccc aaaataaacc
      121 ttcataaatc gccagatatc tctttgcgtc aggccaatat tcattgatga gaaatataaa
      181 ccaatcaggt ctttatcgcg ccagcggcgc ggtacttttg cacgtatctg tgcccgatgc
      241 agatcgataa ctgaaatttt taattcatct tcccggccag taaatggcaa atgaagcaaa
      301 aagtggcaaa tgtaacagtc gcggtgattt atccctgcag tatgcatttt acgcaccata
      361 gttgctacac gtgcgatcag catacgctta acacgtatat caggcgggtt gactgcccaa
      421 tcggcacaat aatcttcaag gctaattgtg ggagtgagat cttcggtaat aataaatgat
      481 gcgcgagtta atggatttaa ccctttttcg ccaaacccaa tgcccttcat tgtatcaacg
      541 ccaacatcac tcaggcgatg aatagcgtgc cactctctgt ctgcgcccaa aacgggcatc
      601 cgcaatgaga gtagattttt tataatctct tttaatgtcg tccccttgtg ccatttaaga
      661 aaatagcttt tcccggacag ttcaaagcgt aatgtacgac gagtctccag ttcacgaaag
      721 acctcgccgt tcagtttttt gacctctgca aaagcatctt taccacgcca aagtgtggca
      781 agcggctctt ttaattcaac catctaaacc acctgtaatg atatccgcgg ctttttctgg
      841 caagctatac aaatcctgag tatcggcata atggcgagca ttctccgccc aggccattcg
      901 caatggcgac tgagttaacg ctttacgtaa aacttcattt aattgttcct gagagaaagg
      961 ttcagcgatg accgttccac aattggcatc cgcaatataa tgcgcgtacc cacataccgc
     1021 tgttgttaaa acaggtaacc cagcagtgat cgcttctaga agaacgatac ccgcggcttc
     1081 ctgataagcg ggatgcagta ataaatcagc ggctgccatt aattctgaca catcattgcg
     1141 accggagaag aaatgcacat tgctccgcac gccgagtttt tctgccagcg cttcaaattt
     1201 tcgcggctta tcctgaccaa caacaaataa aagcgtattg tgacgtaatg attccggtaa
     1261 cgatgccaaa gcttcaattg agcgatctac acctttacgg ccaaaatctg atccaacctg
     1321 cagtaataag ttttgttgct cttttatgcc atttttctgg cgataaattt cacggctgtt
     1381 tgggatttgc tcactgtatt ttctgtctgg ataaataccg ggaggaagaa tttgaaaacg
     1441 ttcaggttca gtttgataat gcttctggaa atcggcgatt tgcttatcgg tcagcatcat
     1501 aagtttcgtc gatttaccct gctcgaaagt cgctcgctca aatgcggcat aatggcgata
     1561 tcgtgatgtt aaacgatata aaaaaccttt ttcttgcgca actttctcgg cgtaacaaac
     1621 atcagcggca aaataaacat ccaggccagg catcttatta aacccaacaa cgcgatctgc
     1681 gggatgctct ttgagatgat tttgtaccca ggcataatat tctgcattgc gtccatggtt
     1741 ggtatgggac ttaactggca cctgaataag ctcaaatgct ttcgggcaat cgccttccca
     1801 cgactgtgta tatacccgaa catggtggcc ccgtgcggca actgttgatg caatgcgcat
     1861 aaagtcacgt tgaagcccac caaatggaaa atatttatat aaacaaaacg ccacgatcat
     1921 aattgtgcat tcctgtcagc tgaaggggca tcttctggca acagcttttc cgtagcggcg
     1981 atcacatcct ccgctgggat aacagaaaga tattttttgt tgcggtcaag ttcatgccgg
     2041 gtcggcattt tctgataatt ccccgcccag aattgaataa tattctcggt ccagggacgc
     2101 cagaatacgt gatccgttgc accaaataga ctaatgactg gcgttttcac tgccgctgca
     2161 atatgtcccg gcgcagaatc cacaccaata aaaagcactg catgatcaat taatgcaccc
     2221 agttcaggaa aacgtgtttt acctgcaagg ccagtaatgg gttttgtttc gcaacctcgt
     2281 gcaatctcat ctacacaagc gagatcatct gccgagggcc cacaggttag cacaacctga
     2341 tagcctcgct gttgcagcgc atcgataacc ttagaaaatt tatcgttatc ccaacactta
     2401 aatatctgac gcgctgtcgg ttggatgaca acataatgat cttttacgcc cagggcatct
     2461 aattcccggc gcatcttctt ccagcaatct tcggcgtaac tcattgttgt gtcggtgtag
     2521 aaatcggtaa tacctaatgg ctcaaggacc gataaattac gctcaacaat atgtgtaccg
     2581 tgtattggcg ctaagtgtgt gaagcttttt ttccaaatac catgctgccg atgaccataa
     2641 agttgcgata ttttcatccg tgcaggtaaa caacgtacca gcagcgccac catccactga
     2701 tccgtaagat taatgaccag gtcataatta ttcgcacgca gagtttttat caacgaaagc
     2761 acatttttaa ttttatcgaa agttcccgca cctttattgc ttatcccata gagcgcatta
     2821 atttccgggt tttcagacaa aatagggatg gtgtcctgat aaagcagcat atcgattttt
     2881 gcatcaggat aattctgctt gagcgtactg atgacaggag tagttaataa catatcccca
     2941 tgatatcgca tctttatgac caggattttt cgaaatggct tttccactag cgactctttt
     3001 gtgtgattgt ctggttaagt taagcagaaa aaagcacgct accgccccag gctcaacagc
     3061 tacctgaata ctgataacgc acttactttg acgtgctagt gtatcatttc tttcgcagca
     3121 atccgacccg aatgattttt atacacaaaa tatactttaa tcataaaaat caaatagata
     3181 aaaaatagca tttcgataat gtcagtacgg cctatgtaga tttgaaaatg gggccgagtt
     3241 tcaatgaatc gcataaaaat acaaaaaaaa tgaagatgta gcggcagatc agaccaaact
     3301 gaagctattt aagtcaaaaa cgggaaaagt aatggtaaag ccacagctaa atacatagaa
     3361 tccccagcac atccataagt cagctattta ctatgctcga attgctttac accgcccttc
     3421 tctaccttat tcagccgctg atctggatac ggctctgggt gcgcggacgt aaggctccgg
     3481 cctatcgaaa acgctggggt gaacgttacg gtttttaccg ccatccgcta aaaccaggcg
     3541 gcattatgct gcactccgtc tccgtcggtg aaactctggc ggcaatcccg ttggtgcgcg
     3601 cgctgcgtca tcgttatcct gatttaccga ttaccgtaac aaccatgacg ccaaccggtt
     3661 cggagcgcgt acaatcggct ttcgggaagg atgttcagca cgtttatctg ccgtatgatc
     3721 tgcccgatgc actcaaccgt ttcctgaata aagtcgaccc taaactggtg ttgattatgg
     3781 aaaccgaact atggcctaac ctgattgcgg cgctacataa acgtaaaatt ccgctggtga
     3841 tcgctaacgc gcgactctct gcccgctcgg ccgcaggtta tgccaaactg ggtaaattcg
     3901 tccgtcgctt gctgcgtcgt attacgctga ttgctgcgca aaatgaagaa gatggtgcac
     3961 gttttgtggc gctgggcgca aaaaataatc aggtgaccgt taccggtagc ctgaaattcg
     4021 atatttctgt aacgccgcag ttggctgcta aagccgtgac gctgcgccgc cagtgggcac
     4081 cacaccgccc ggtatggatt gccaccagca ctcacgaagg cgaagagagt gtggtgatcg
     4141 ccgcacatca ggcattgtta cagcaattcc cgaatttatt gctcatcctg gtaccccgtc
     4201 atccggaacg cttcccggat gcgattaacc ttgtccgcca ggctggacta agctatatca
     4261 cacgctcttc aggggaagtc ccctccacca gcacgcaggt tgtggttggc gatacgatgg
     4321 gcgagttgat gttactgtat ggcattgccg atctcgcctt tgttggcggt tcactggttg
     4381 aacgtggtgg gcataatccg ctggaagctg ccgcacacgc tattccggta ttgatggggc
     4441 cgcatacttt taactttaaa gacatttgcg cgcggctgga gcaggcaagc gggctgatta
     4501 ccgttaccga tgccactacg cttgcaaaag aggtttcctc tttactcacc gacgccgatt
     4561 accgtagttt ctatggccgt catgccgttg aagtactgta tcaaaaccag ggcgcgctac
     4621 agcgtctgct tcaactgctg gaaccttacc tgccaccgaa aacgcattga ggttgttatg
     4681 caaaaacggg cgatttatcc gggtactttc gatcccatta ccaatggtca tatcgatatc
     4741 gtgacgcgcg ccacgcagat gttcgatcac gttattctgg cgattgccgc cagccccagt
     4801 aaaaaaccga tgtttaccct ggaagagcgt gtggcactgg cacagcaggc aaccgcgcat
     4861 ctggggaacg tggaagtggt cgggtttagt gatttgatgg cgaacttcgc ccgtaatcaa
     4921 cacgctacgg tgctgattcg tggcctgcgt gcggtggcag attttgaata tgaaatgcag
     4981 ctggcgcata tgaatcgcca cttaatgccg gaactggaaa gtgtgtttct gatgccgtcg
     5041 aaagagtggt cgtttatctc ttcatcgttg gtgaaagagg tggcgcgcca tcagggcgat
     5101 gtcacccatt tcctgccgga gaatgtccat caggcgctga tggcgaagtt agcgtagcgt
     5161 ttatgccgga tggtatgcca tccggcgcgc atgaattact tctggcactg ccgacaataa
     5221 aacgttgccc gctgcgcatg tttagtcgcc acaatcggcg taccgcacac ccgacacggc
     5281 tcaccttttc gcccgtaaac ctgcaattcc tgagcgaaat agcccggttt accatcactt
     5341 tgcagaaaat ctttcagcgt tgtaccaccc tgctcaatcg aacgcagcaa caccgcttta
     5401 atcacccgag ctaacaattc acactctgcc agcgacagtg atgacgccag ccgatccgga
     5461 tggatccccg ccgcaaacag tgattcgctg gcatagatat tccctacccc taccaccagc
     5521 ttgttatcca tcagccacgg tttaatcgcc gtttttttct tcgcgcactt ctgatgcaga
     5581 tactcaccat tgaaatcgtc gctaagcggc tccggtccaa gatgggtcag cacattatgc
     5641 ccttccagct ctttggtcca cagccaggca ccaaagcggc gcggatcggt gtagcgcagc
     5701 actttgccgt tgctcatcac caaatccaca tggtcatgct tttcaggggg aagttcttct
     5761 ggaaggatgc gcaggctgcc agacatccct aaatgaatga taatccagcc ctcaggcagc
     5821 tccagcagca gatatttagc ccgccgctgc acgctaagca ctggttggtc gcttaaacgg
     5881 tagatctctt ctgaaaccgg ccagcgcaag cgtccgttgc gcaccactgc atgaagaatg
     5941 gttgcaccaa cgagatgcgg ttctatgccg cggcggctgg tttcaacttc gggtaattca
     6001 ggcatagcat ctccaggaat gaacagatgc agtcaatatg ggggcaagca gataacaaaa
     6061 aaccccgccg gagcgaggtt ttttgttaca tcaaagcgag aattatttga ttttcgcttc
     6121 tttgtagatc acgtgctggc gaacaactgg atcgaatttt ttcagttcca gtttttccgg
     6181 cttagtacgt ttgttcttcg tagtggtata gaagtgacca gtaccagcag aagaaaccag
     6241 cttgattttc tcacgaatac ctttagccat gatttatttc ctctaagtac ttagtacttt
     6301 tcgccacggg cacgcagttc agccagaact gtatcgatgc cttttttatc gattacacgc
     6361 atacctttag cagatacgcg cagggtgaca aaacgcttct cgctctcaac ccagaaacgg
     6421 tgagagtgca ggttcggcag gaaacggcgt ttagtcgcgt tcagtgcgtg ggaacggttg
     6481 ttaccggtca ccggacgctt gccagtaact tggcagactc gggacatgtc tattctccaa
     6541 aaatcaaatt agctcgagct tcgtatgggg tattggcgcc tcgtcaggct ttacagcccg
     6601 gtcatcgcag ttctatgtga actctcgatt gccaggccca aatgccaaac ccgagattct
     6661 caaaggtggc gtagtatacg ctgactcagc gatgtgctca agtcccgaac agacaaagat
     6721 cccgaaggat cgcgcatagc gggttaaatc cagccgcgtt cggcaaaaga aacatactct
     6781 ccacgcccaa tcacgatatg gtcgagcacg cgtaaatcca tgaactgaca actctttatt
     6841 atccgttcag taatgagttt atccgcttta ctgggttcag cacaacccga agggtgatta
     6901 tgtgcaagga tcagcgccga ggcgtttatt tttatcgctt cgcggataat ttcccgagga
     6961 tggacttcaa catggtttag cgtgccggaa aaaagacgcc tatgcgttat aacccggtgt
     7021 tgggagtcga gaaagatcac cataaagatc tcccgctcct cacccgtgag ctggctttgt
     7081 aaaaattccc tcgtcatctc cgggctgagt aaagggcttt cttcacgcat ccgcacgttg
     7141 tagtaacgcc gcgccagttc agcaatcccc tttaactggg caaatttcgc cacgccaatt
     7201 ccatgaacgc cactaaattg ttcatattca gaggttaaca agccataaag agagccgaaa
     7261 ttctccagca tctcttttgc cagggttaat acatctttac cgcgcgttcc ggtacgcaga
     7321 aatagcgcca gcagctcgac atccgttaag gcgctaatac caaacttcag cattttttcg
     7381 cgcggcatca acagctgtga attgtttttc accttcacct cctttgtggt gctcgcatcc
     7441 tgtcatagcc gtttcgttaa atcgacggcc agttttcaat cctggaaagc gcctcgcaaa
     7501 gtgaatctca ggtgaaggca cgacaacaaa agtattgtga taaaatcgcc aacttctggt
     7561 gtcaccctac aggaaaaatc atcatgagcc tggccggtaa aaaaatcgtt ctcggcgtta
     7621 gcggcggtat tgctgcctat aaaacccctg aactggtgcg tcgtttgcgc gatcgcgggg
     7681 ccgacgtccg cgtagccatg accgaagcgg caaaagcctt tatcacccca cttagcttgc
     7741 aggcggtttc tggttatccc gtttccgaca gtctgctgga cccggcagcc gaagccgcta
     7801 tgggccatat tgagctgggt aaatgggctg atttagtgat tctcgcccct gccacggcag
     7861 atttgattgc ccgtgttgct gccggaatgg cgaatgacct ggtatcgacg atttgtctgg
     7921 ctacacctgc gcctgtagcc gtgctccccg ccatgaacca gcagatgtac cgtaccgctg
     7981 ccacgcagca taatttagag gtgcttgctt cccgtggttt gctcatctgg gggccagaca
     8041 gtggcagtca ggcttgtggt gatatcggtc ctgggcgaat gctcgatccg ttaaccattg
     8101 tggatatggc ggtagcgcat ttttcgcccg tcaacgacct gaaacatctg aacattatga
     8161 ttaccgccgg cccgacgcgt gaaccgctcg atccggtgcg ttatatctct aatcacagct
     8221 ccggcaagat gggttttgct atcgccgccg ccgctgcccg tcgtggcgcg aacgtcacgc
     8281 tggtatcagg tccggtttca ctaccgacgc caccgtttgt taaacgtgtt gatgtgatga
     8341 ccgcgctgga aatggaagcc gccgtgaatg cttctgtaca gcagcaaaat atttttatcg
     8401 gctgcgccgc cgtggcggat tatcgcgcag ctaccgtggc cccagagaaa atcaaaaagc
     8461 aggccacgca gggtgatgaa ttaacaataa aaatggttaa aaaccccgat atcgtcgcag
     8521 gcgttgccgc actaaaagac catcgaccct acgtcgttgg atttgccgcc gaaacaaata
     8581 atgtggaaga atacgcccgg caaaaacgta tccgtaaaaa ccttgatctg atctgcgcga
     8641 acgatgtttc ccagccaact caaggattta acagcgacaa caacgcatta caccttttct
     8701 ggcaggacgg agataaagtc ttaccgcttg agcgcaaaga gctccttggc caattattac
     8761 tcgacgagat cgtgacccgt tatgatgaaa aaaatcgacg ttaagattct ggacccgcgc
     8821 gttgggaagg aatttccgct cccgacttat gccacctctg gctctgccgg acttgacctg
     8881 cgtgcctgtc tcaacgacgc cgtagaactg gctccgggtg acactacgct ggttccgacc
     8941 gggctggcga ttcatattgc cgatccttca ctggcggcaa tgatgctgcc gcgctccgga
     9001 ttgggacata agcacggtat cgtgcttggt aacctggtag gattgatcga ttctgactat
     9061 cagggccagt tgatgatttc cgtgtggaac cgtggtcagg acagcttcac cattcaacct
     9121 ggcgaacgca tcgcccagat gatttttgtt ccggtagtac aggctgaatt taatctggtg
     9181 gaagatttcg acgccaccga ccgcggtgaa ggcggctttg gtcactctgg tcgtcagtaa
     9241 cacatacgca tccgaataac gtcataacat agccgcaaac atttcgtttg cggtcatagc
     9301 gtgggtgccg cctggcaagt gcttattttc aggggtattt tgtaacatgg cagaaaaaca
     9361 aactgcgaaa aggaaccgtc gcgaggaaat acttcagtct ctggcgctga tgctggaatc
     9421 cagcgatgga agccaacgta tcacgacggc aaaactggcc gcctctgtcg gcgtttccga
     9481 agcggcactg tatcgccact tccccagtaa gacccgcatg ttcgatagcc tgattgagtt
     9541 tatcgaagat agcctgatta ctcgcatcaa cctgattctg aaagatgaga aagacaccac
     9601 agcgcgcctg cgtctgattg tgttgctgct tctcggtttt ggtgagcgta atcctggcct
     9661 gacccgcatc ctcactggtc atgcgctaat gtttgaacag gatcgcctgc aagggcgcat
     9721 caaccagctg ttcgagcgta ttgaagcgca gctgcgccag gtattgcgtg aaaagagaat
     9781 gcgtgagggt gaaggttaca ccaccgatga aaccctgctg gcaagccaga tcctggcctt
     9841 ctgtgaaggt atgctgtcac gttttgtccg cagcgaattt aaataccgcc cgacggatga
     9901 ttttgacgcc cgctggccgc taattgcggc acagttgcag taatatgacg ccggatgact
     9961 tttcatccgg cgagtttctt taaacgccaa actcttcgcg ataggcctta accgccgcca
    10021 gatgttccgc catttccggc ttctcttcca ggtaagcaat caggtctttc agggtgatga
    10081 tagagatcac tttgcagttg taatcacgct caacttcctg aatcgccgaa atctcgccgc
    10141 gcccgcgttc ctgacgatcg agcgaaatca acacgccagc aagcgtcgcg ccattggcct
    10201 gaataatctc catcgactcg cgaatcgccg ttccggcggt gatcacatca tctaccagca
    10261 ttacgcgtcc ttgtaacgcg ctaccaacca gattgccgcc ttcaccgtgg tcttttgctt
    10321 ctttgcggtt aaagcagtac ggcaggtcca ggtcgtgatg ctccgccagt gccacagcgg
    10381 ttgtggtggc aatcgggatc cctttgtaag cagggccaaa cagcagatcg aactcaatgc
    10441 cggaatccac caacgcttca gcgtaaaaac ggcctaacag tgccagatcg cgcccggtat
    10501 taaacagccc ggcgttgaag aaataggggc ttttgcgccc ggatttcagc gtaaactcgc
    10561 caaactttaa cacctgcttg ctaagcgcaa attcaataaa ctggcgctga tatggtttca
    10621 tgccttcgct cctcatctta cttttctaca gacaaaaaaa aggcgactca tcagtcgcct
    10681 taaaaatcag tttgccagcg ccgccttctg cgtcgctaca atggattcga ttccccctcg
    10741 ggccagagcc aacaaggtga gtagctcttc atgggtgaac ggctcgcctt ctgccgtccc
    10801 ctgcacttca atgatgcgcc cgtcttcggt catcactacg ttcatgtcgg tctctgcggc
    10861 agagtcttca acgtattcca gatcgcaaac cgcttcgccg ttcacaattc cgacagaaac
    10921 tgcggctacc atccctttca tcggattggt tttcagcttg ccgttttcca ccagcttctg
    10981 tagcgcatct accagcgcca cgcaggcacc cgtaatcgac gcggtacgcg tgccaccatc
    11041 agcctgaagc acgtcgcagt ccagcgtaat ggtgaactca cccagcgctt tcaaatctac
    11101 tgccgcgcga agagcacggg cgatcagacg ctggatttcc attgtgcgtc caccctgctt
    11161 acctttcgcc gcttcacgag cgttacgggt gtgggtagaa cgtggcagca tgccgtactc
    11221 tgcggtgatc cagccctggc cctgaccttt caggaagcgc ggcacgcctt cttcaataga
    11281 ggcggtacac aacactttgg tatcgccaaa ttcgaccagc accgagcctt ctgcatgttt
    11341 tgtatagtta cgagtcaggg taacgggacg cacctgatta ttgctacggc ctgctggacg
    11401 catattgaaa tctccggctt gaaacaaatg tggctgcgca ttatacggac ttccggcggt
    11461 tattcctatc ctgacaaggc atcgatggct ataatccttc cacctctcct tttataaaca
    11521 ggaacgtcta tgatccgcag tatgaccgcc tacgcccggc gtgaaatcaa gggtgaatgg
    11581 gggagcgcaa cctgggaaat gcgctcggta aaccagcgtt atctggaaac ttactttcgt
    11641 ctgccggagc agttccgtag ccttgaacct gtcgttcgcg agcgtattcg ttctcgcctg
    11701 acgcgcggta aagtggaatg taccctgcgc tatgagccag atgttagcgc gcaaggtgag
    11761 ctgatcctca acgaaaaact ggctaaacag ctggtaactg ccgcgaactg ggtaaaaatg
    11821 cagagtgacg aaggggaaat caacccggtt gatattctac gctggccggg cgtgatggca
    11881 gcccaggagc aggatcttga cgccattgcc gctgaaattc tcgcggcgct ggatggtacg
    11941 ctggacgact ttattgtcgc gcgcgaaacc gaaggtcagg cactgaaagc attgatcgag
    12001 cagcgtctgg aaggcgtcac cgccgaagtg gtcaaagtcc gctcccatat gccggaaatc
    12061 ctgcaatggc agcgtgagcg tctggtcgcg aagctggaag atgctcaggt gcaactggaa
    12121 aacaaccgtc tggagcagga actggttctg ctggcacaac gaattgacgt tgccgaagaa
    12181 ctggatcgcc tcgaagcgca tgtcaaagag acctacaaca ttctgaagaa aaaagaagcg
    12241 gttggtcgtc gtctggattt tatgatgcag gagttcaacc gcgagtcgaa cactcttgcg
    12301 tcgaagtcta tcaatgccga agtgacaaac tccgccatcg agctgaaagt gttgattgag
    12361 cagatgcgcg agcagattca gaacatcgaa taactcgtaa cgccaattct tacttttccg
    12421 ccttcacaaa tgccgccact caaacagagc ggcatttttc ttccccgcaa cattcaattc
    12481 tgttttgcgt gcctgctcca gattttgcga tgtttttttg cccagcacac tgagaacgtg
    12541 agatactcac aactgtatat aaatacagtt acagatttac tttctttgca attgatatca
    12601 catggagtgg gcaatgaacg aacatcatca accttttgaa gagataaaac tgattaatgc
    12661 aaacggagca gaacaatggt cagcaagaca acttgggaaa ctactgggtt attcagagta
    12721 tcgtcacttt atacctgtat taacgcgcgc caaagaagcc tgtgagaaca gtggtcacac
    12781 aattgatgac catttcgagg agatcctcga tatggtcaaa attggctcaa atgccaaaag
    12841 agcattaaaa gacatcgtac tctcccgcta tgcctgttac ctggtagtac aaaacggcga
    12901 ccctgcgaaa ccggtcattg cggcagggca gacttatttt gctatccaga cccgacggca
    12961 ggagcttgct gacgatgaag catttaagca acttcgtgaa gacgaaaagc gtctgtttct
    13021 gagaaatgag ttgaaagaac ataacaaaca attggttgag gcagcacagc aagctggggt
    13081 agcgacagct actgatttcg ccatatttca gaatcatggt taccaggggc tgtatggtgg
    13141 attagatcag aaagctattc atcagcggaa ggggctgaaa aagaatcaga agatcctgga
    13201 tcatatgggt tcaacagaac tggcggctaa tctctttcga gctacccaaa cagaagaaaa
    13261 actcaagcgg gatggcgtga attcaaaaca gcaagcaaac accacacact ttgacgtggg
    13321 tcgcaaggtg aggcaaacca ttcaggaact tggcggaacc atgcctgagg agttgccgac
    13381 cccgcaggtc agcatcaagc agttggaaaa cagtgtaaaa attacagaga agaaatagca
    13441 gaaactaaaa actctttttg ttgattgaga cacccgatgc gtaagccaag gtccaggtgc
    13501 agtgaacaca atggctaaat attgcacctt tcttttcccc cctcagtttt aacctatttt
    13561 ttcttatgca ttttctcaga caagaagtca gaagaatgca tctctgctac agaaaatagc
    13621 gatttcacat aactacaagt tatcaatttc ccctcccctt aaaaaatctc aatcgtgaca
    13681 atgcgcacaa atcgctaccc tgccagacag atttttaggg agagaaccat gctgttacac
    13741 attttgtatt tggttggcat tactgccgaa gccatgacgg gggcgctggc ggccggacga
    13801 cggcgcatgg atacatttgg cgtaattatt attgcgaccg ccaccgcaat tggcggaggg
    13861 tcagtgcgcg atattctgct gggccactat ccgctcggct gggtcaaaca cccggaatat
    13921 gtgattatcg tcgctaccgc cgcagtactc accactatcg ttgctcctgt aatgccttac
    13981 ctgcgcaaag tgtttctggt gctcgatgcg ctcggactgg tggtcttttc tatcatcggg
    14041 gcacaggttg cactggatat ggggcacggc ccaattattg ccgttgtcgc ggcggtaacc
    14101 accggcgtgt ttggcggcgt tttgcgcgat atgttctgta aacgtatccc actggtattc
    14161 cagaaagagt tgtatgccgg tgtctcattt gcctccgccg tgctgtacat cgcgctgcaa
    14221 cactatgttt ctaaccatga tgtggtaatt atctccaccc tggtattcgg cttttttgcc
    14281 cgcttactgg cgctacgcct taagctggga ttaccggtct tttactacag ccacgaagga
    14341 cactaaggtt caaaacctgt gatctgctgg gcagccagcc aactgcccag cttcttgatt
    14401 tgcgcatttt ccttccattc aataacctgt ctggcgcgtc ccgatccagt ccccggcagc
    14461 tgctgccaga actgctccgt gctaaataaa agttgcgacc aggaccgttc atcactggca
    14521 ttaagcgccg cccgggttag cggtattccc attgccatca cccagcgagt aaaaggctgc
    14581 ttacgagcca gattaaactg atgccatagc tgcgcacttt tacttttcgc gatccccggc
    14641 gtgttctgta attgctctgg cgttaataaa agccaggaaa agatatgttc aaagcgatga
    14701 gtctgatgca gcgcgcgcca accggcctca ccaatgccat ccagcccaag aacctgtttt
    14761 gcccccagcc agactaagcg tgaaatgaac tgttcctgac aaacatcaga agcaaagtag
    14821 caggtcaacg agttaaagcg gttttctggc ggtgtcggtt ttgtacgttc tgcaccgcgc
    14881 cacaccacat catcaatgcg aggaataccc tgaccggcaa ggctgacgag aatctgatca
    14941 ccaggcgcaa tatcccactc ctgccagcgc ctgacggaac caatattcac ccgctggact
    15001 tttttatcat ccagcatgac aggtgcgagt gacgcaacca ccgatatttt accgctctta
    15061 cccaccgcaa actgaattgc cttcacttcg gcaacctgag ctacaggttg atatttccag
    15121 gccaccagcc actctgcctg gcccggtagc caatggcggg attctggctc tttcgccgct
    15181 cgtacaacta cgccatcggt gacgaagggt aattccgctt tccaccactc attgcgtacg
    15241 cgcgcaactt catcagcatt tttcaccgca cgggtatacg tctgcgttag agtaaaacct
    15301 gcggtagcca gctcttttaa acgatcagac attaactgcg gtccatccgg ccatgcccag
    15361 acaaaaacgc ccagagaatt cagcgtgtcg ctatcgtcct ggcgcatcat caagccagca
    15421 acttttgcgc gggcatttat tccccccatt tgttgttgga tatgcccctc gcgctggaga
    15481 aatatttccc cctgaagcgt actgttggct aaaggcccgc taacggtttg cggcacagcg
    15541 gaaattaagc taactttctg cgtccagtcc tcgcctttca ggccattacc gcgactgatt
    15601 gctttgttca gtttcccgtc ccgataaacc agggttaccg caacgccatc aacttttggc
    15661 tgcacccaaa gatcgctacg ttctcgcatc cacagactta atgcgttttt atccaccatt
    15721 ttgcgtacac ccgtatgggc aaccggatgc ataaccgcac catttaaagg cggcatcatc
    15781 acgtcgcggg gctcgctccc aaagcagcgt tgccactgcg taagacgggc gcttaactga
    15841 tcgtaaacac cgtcttccac ctcacttttt ccttccttcc agtagtcatc gtcccactgt
    15901 tttatttgct gttgcaggcg ggaaatttct tcctgtgctc tggctggcga ccaggccgga
    15961 cagaccgccc acacagatga ttgccagcac aagataccta ttaatatcgc catccatact
    16021 ttcatcatca cctccgctgt agatagtcag gcagatatac aacgtgatga aagcaaagcc
    16081 gagtggcaaa aacggagtct gcgaggacgc ttcctgaaaa tcgtctttat tgcagtgaat
    16141 gacaggcaaa tgcggaagca gctacgcaaa acgcaacaac tttgcgcaaa aagtgtgagc
    16201 aagggctacg tcacatggcc gcgccgtgta taataagctc gtatgtaggc tttatttcgc
    16261 taatcacata cgaaagatac tcatggctca aggcacgctt tatattgttt ctgcccccag
    16321 tggcgcgggt aaatccagcc tgattcaggc tttattaaaa acccaaccgt tgtatgacac
    16381 ccaggtttct gtttcacaca ccacacgcca accgcgtcct ggtgaagtcc acggtgaaca
    16441 ttatttcttt gttaatcatg atgaatttaa agaaatgatt agcagagatg cgttcctcga
    16501 acacgcagaa gtttttggta attactatgg cacttcgcgt gaggccattg agcaagtact
    16561 ggcgaccggt gtcgatgttt ttctcgatat cgactggcag ggcgcgcagc aaattcgcca
    16621 gaagatgccg cacgcgcgga gtatctttat tttaccgccg tccaaaattg aactggaccg
    16681 ccgtctacgc ggtcgcggtc aggacagcga agaggtcatt gcaaagcgta tggcgcaagc
    16741 tgttgcagaa atgagccatt acgccgaata tgattatctg attgtgaatg atgacttcga
    16801 taccgcgttg accgatttga agaccattat tcgcgccgaa cgtctgcgca tgagccgcca
    16861 aaagcagcgt catgacgctt taatcagcaa attgttggca gactgaacct gatttcagta
    16921 tcatgcccag tcatttcttc acctgtggag ctttttaagt atggcacgcg taactgttca
    16981 ggacgctgta gagaaaattg gtaaccgttt tgacctggta ctggtcgccg cgcgtcgcgc
    17041 tcgtcagatg caggtaggcg gaaaggatcc gctggtaccg gaagaaaacg ataaaaccac
    17101 tgtaatcgcg ctgcgcgaaa tcgaagaagg tctgatcaac aaccagatcc tcgacgttcg
    17161 cgaacgccag gaacagcaag agcaggaagc cgctgaatta caagccgtta ccgctattgc
    17221 tgaaggtcgt cgttaatcac aaagcgggtc gcccttgtat ctgtttgaaa gcctgaatca
    17281 actgattcaa acctacctgc cggaagacca aatcaagcgt ctgcggcagg cgtatctcgt
    17341 tgcacgtgat gctcacgagg ggcaaacacg ttcaagcggt gaaccctata tcacgcaccc
    17401 ggtagcggtt gcctgcattc tggccgagat gaaactcgac tatgaaacgc tgatggcggc
    17461 gctgctgcat gacgtgattg aagatactcc cgccacctac caggatatgg aacagctttt
    17521 tggtaaaagc gtcgccgagc tggtagaggg ggtgtcgaaa cttgataaac tcaagttccg
    17581 cgataagaaa gaggcgcagg ccgaaaactt tcgcaagatg attatggcga tggtgcagga
    17641 tatccgcgtc atcctcatca aacttgccga ccgtacccac aacatgcgca cgctgggctc
    17701 acttcgcccg gacaaacgtc gccgcatcgc ccgtgaaact ctcgaaattt atagcccgct
    17761 ggcgcaccgt ttaggtatcc accacattaa aaccgaactc gaagagctgg gttttgaggc
    17821 gctgtatccc aaccgttatc gcgtaatcaa agaagtggtg aaagccgcgc gcggcaaccg
    17881 taaagagatg atccagaaga ttctttctga aatcgaaggg cgtttgcagg aagcgggaat
    17941 accgtgccgc gtcagtggtc gcgagaagca tctttattcg atttactgca aaatggtgct
    18001 caaagagcag cgttttcact cgatcatgga catctacgct ttccgcgtga tcgtcaatga
    18061 ttctgacacc tgttatcgcg tgctgggcca gatgcacagc ctgtacaagc cgcgtccggg
    18121 ccgcgtgaaa gactatatcg ccattccaaa agcgaacggc tatcagtctt tgcacacctc
    18181 gatgatcggc ccgcacggtg tgccggttga ggtccagatc cgtaccgaag atatggacca
    18241 gatggcggag atgggtgttg ccgcgcactg ggcttataaa gagcacggcg aaaccagtac
    18301 taccgcacaa atccgcgccc agcgctggat gcaaagcctg ctggagctgc aacagagcgc
    18361 cggtagttcg tttgaattta tcgagagcgt taaatccgat ctcttcccgg atgagattta
    18421 cgttttcaca ccggaagggc gcattgtcga gctgcctgcc ggtgcaacgc ccgtcgactt
    18481 cgcttatgca gtgcataccg atatcggtca tgcctgcgtg ggcgcacgcg ttgaccgcca
    18541 gccttacccg ctgtcgcagc cgcttaccag cggtcaaacc gttgaaatca ttaccgctcc
    18601 gggcgctcgc ccgaatgccg cttggctgaa ctttgtcgtt agctcgaaag cgcgcgccaa
    18661 aattcgtcag ttgctgaaaa acctcaagcg tgatgattct gtaagcctgg gccgtcgtct
    18721 gctcaaccat gctttgggtg gtagccgtaa gctgaatgaa atcccgcagg aaaatattca
    18781 gcgcgagctg gatcgcatga agctggcaac gcttgacgat ctgctggcag aaatcggact
    18841 tggtaacgca atgagcgtgg tggtcgcgaa aaatctgcaa catggggacg cctccattcc
    18901 accggcaacc caaagccacg gacatctgcc cattaaaggt gccgatggcg tgctgatcac
    18961 ctttgcgaaa tgctgccgcc ctattcctgg cgacccgatt atcgcccacg tcagccccgg
    19021 taaaggtctg gtgatccacc atgaatcctg ccgtaatatc cgtggctacc agaaagagcc
    19081 agagaagttt atggctgtgg aatgggataa agagacggcg caggagttca tcaccgaaat
    19141 caaggtggag atgttcaatc atcagggtgc gctggcaaac ctgacggcgg caattaacac
    19201 cacgacttcg aatattcaaa gtttgaatac ggaagagaaa gatggtcgcg tctacagcgc
    19261 ctttattcgt ctgaccgctc gtgaccgtgt gcatctggcg aatatcatgc gcaaaatccg
    19321 cgtgatgcca gacgtgatta aagtcacccg aaaccgaaat taatgtttta tgaacccaac
    19381 acgttatgca cgcatctgcg aaatgctcgc caggcggcag cctgatctga ccgtctgcat
    19441 ggagcaggtc cacaaacctc ataacgtttc tgcgattatt cgtaccgcag atgccgttgg
    19501 cgtacatgaa gttcacgccg tctggcctgg tagccgcatg cgcaccatgg cttcggcagc
    19561 ggcgggtagt aacagctggg tacaggtgaa aacacaccgc accattggcg atgccgtcgc
    19621 tcatctcaaa ggccagggca tgcagattct ggcaacccat ctttctgata acgctgtcga
    19681 tttccgcgaa attgattaca ctcgcccgac ctgcattttg atgggacagg agaaaacggg
    19741 catcacgcag gaagcattgg ccctggcgga tcaggacatc atcattccga tgatcggcat
    19801 ggtgcagtcg ctgaatgttt ccgttgcctc agccctcatt ctttacgaag cccagcgtca
    19861 gcggcaaaat gcaggcatgt acctgcgtga aaacagcatg ttgccggaag cagagcaaca
    19921 acgcctgttg tttgaaggcg gctatccggt gctggcgaaa gtcgcaaaac gcaaaggcct
    19981 gccttatccc cacgtcaatc agcaaggcga gatcgaagct gatgccgact ggtgggctac
    20041 tatgcaggct gcagggtaag tgccatgaaa ggtcgcctgt tagatgctgt cccactcagt
    20101 tccctaacgg gcgttggcgc agcacttagt aacaaactgg cgaaaatcaa cctgcatacc
    20161 gtgcaggatc tactcttaca ccttcccctg cgctacgaag atcgcaccca tctctacccc
    20221 atcggagaac tactgccggg cgtttatgcc acggtggaag gcgaagtgct gaactgcaat
    20281 atctccttcg gcggtcggcg gatgatgacc tgccagatca gcgacggttc cggcatcctc
    20341 accatgcgct ttttcaattt cagcgcggca atgaaaaata gcctggcggc gggccgccgt
    20401 gtactggctt atggcgaagc aaagcgcggt aaatatggtg cggagatgat ccacccggaa
    20461 taccgcgtgc agggcgatct cagcacgcca gaattacagg aaacgctcac gccggtttat
    20521 ccaacaacgg aaggcgtaaa gcaggccacg ctgcgtaaat taaccgacca ggcgctggat
    20581 ctgctcgaca cctgcgccat tgaagaactc ctgccgccgg aactgtcaca aggaatgatg
    20641 acgctaccgg aagcgttgcg cactttgcac cgcccgccac cgacgctaca gcttagcgat
    20701 ctggaaaccg ggcagcatcc ggcgcaacgt cgtctgattc tggaagaact gctggcgcac
    20761 aacctcagca tgttagcctt acgtgccgga gcacagcgtt ttcatgccca gccgctgagc
    20821 gccaatgaca cgctgaaaaa taaactcctc gccgccttac cgttcaagcc aacgggcgca
    20881 caggcacgcg tagtggcgga gatcgagcgc gatatggcgc tggatgtgcc gatgatgcgt
    20941 ctggtgcagg gcgatgtagg ttccggtaaa acgctggtcg ccgccctcgc cgcgttgcgt
    21001 gcgattgccc acggcaaaca ggtagcattg atggcaccaa ccgaattact cgccgagcag
    21061 cacgccaata acttccgcaa ctggtttgca ccgctcggta tcgaagtggg ctggctcgcc
    21121 ggtaagcaga aaggtaaagc acggctggca cagcaggaag ccatcgccag cggtcaggtg
    21181 cagatgattg tcggtacaca cgccatcttc caggaacagg tgcagtttaa cggcctggcg
    21241 ctggtgatta tcgacgaaca gcatcgtttt ggcgtgcatc agcgtctggc attgtgggag
    21301 aaaggccagc agcagggctt ccatccgcat cagttgatca tgaccgccac gccgatcccc
    21361 cgcacgctgg caatgactgc gtatgccgat ctcgatacct cggtgataga tgagctgccg
    21421 ccaggccgca cgccagtgac tacggtcgct attcctgata cccgccgtac cgacatcatt
    21481 gaccgcgtgc accacgcctg cataactgaa ggtcgtcagg catactgggt ttgtacgttg
    21541 attgaagagt cggaattgct ggaagcgcag gcggcggaag ctacctggga agagttgaaa
    21601 ctggcgctac cagagttgaa cgttggcctg gtacacgggc ggatgaaacc tgccgagaaa
    21661 caggcggtga tagcgtcgtt taaacaaggt gagctacacc tgctggttgc cacaaccgtt
    21721 attgaagtcg gcgttgatgt gcctaacgcc agtctgatga ttatcgaaaa cccggagcgt
    21781 ctgggtctgg cgcagttaca ccagctgcgc gggcgcgtag gtcgtggcgc ggtggcttct
    21841 cactgcgtgc tgctctacaa aacgccgctt tctaaaacgg cgcaaattcg cctgcaagtg
    21901 ctgcgcgaca gtaacgacgg ttttgtgatt gcgcaaaaag atctggagat tcgcggccct
    21961 ggcgaattgt taggcacgcg tcagacgggt aatgctgaat ttaaagtggc ggatttactg
    22021 cgcgatcagg cgatgatccc ggaagttcag cgcctggcac gccatattca cgaacgttac
    22081 ccacaacagg caaaagccct gatagaacgc tggatgccgg agacggaacg ttactcgaat
    22141 gcgtaaaagg cggcagtgag aagaccgcca tttcaggtta ccctaccttc ctgccggatg
    22201 cgattcatca ccctacaaat tcaataaatt atgaatcaat acgcaggctt gataagcgaa
    22261 gcgtatcagg catttgtctt tgttgcggcg gcacttctac cgccgcttca tcggttaacc
    22321 ggcaaaaatc ggcaacatca aatacaactt aattaccagc gcattgacga tatcgataaa
    22381 gaacgcaccg accatcggca ccaccaaaaa cgccatgtgc gacgggccaa agcgttcagt
    22441 gatcgcctgc atgttggcga ttgccgttgg cgttgcaccg aggccaaaac cacagtgacc
    22501 cgcagccagc actgccgcat cgtagttttt gcccatcatg cgccaggtaa cgaagatggc
    22561 atacaacgcc atgaagatgg tctgtaccac cagaatcgcc agcatcggca gcgccagcga
    22621 agccagctcc cacagtttca gccccatcaa cgccatcgcc aggaacaacg acaagcttac
    22681 gttacccagc acggataccg cacgctcaaa gacgcggtaa aagcccatta ttgacagacc
    22741 gttgctcaga atcacgccaa caaacagtac acagacgaag gtcggcagtt caaaagcagt
    22801 gccagccaaa agttgcgcaa caattttccc caccgtcagg cagatagcaa tcagcgcgat
    22861 agtttcaatc agcaccaacg aggtgatcat gcgtcccaca tccggctttt caaacgccgt
    22921 cgggacttcc tggtcatccg gaataccgtt cggcgtggtg gagtgtttca ccagatagcg
    22981 cgccaccgga ccgccaatca agccgcccag caccagaccg aacgttgcac aggccatcgc
    23041 cacttccgtc gcattggtga agccataacg ttcaatgaac aatttactcc acgcagcgcc
    23101 cgtaccgtga ccgccggaaa gcgtaataga accggccaac agccccatca gcggatcaag
    23161 ccctaacaag ctagccatac caatgccaat ggcattttgc atcaccaaca gaccaacaac
    23221 cacaatcaag aagatgccaa ccacacgccc accggcacgc aaactggcaa tgttggcgtt
    23281 caggccaatg gtggcgaaga aagccagcat taacggatcg cgcagggaca tatcaaagtt
    23341 gacttcccag cccatgcttt ttttcagtac tagtagcgcc agcgccacca acaaaccacc
    23401 cgcaacaggt tccggtatgg tgtatttctt caaaaaggag acggaatgga ccaacttacg
    23461 cccgagcagc aacgtcagcg ttgcggcaac aagcgttgct aaagtatcga gatgaaacat
    23521 agttactcct ttgtatccgc atcactcttt catactcgtc atacttcatc gcgcagtggc
    23581 aacttcatga actatgacgg gtatcgagtt atgctttcct gggtcaaatt ctcagctgtt
    23641 aatgaacaaa tggcatggat tttaagcaga aaaataccaa aagttatata aaaaagtgca
    23701 tttatctcat ttaaatattt agatgaggat gtggcaaacg tttgcttttc tctttcggtc
    23761 agctaaaatg cccgctttgc taccacggga ttgttttcga tgtctgtttc caccctcgag
    23821 tcagaaaatg cgcaaccggt tgcgcagact caaaacagcg aactgattta ccgtcttgaa
    23881 gatcgtccgc cgcttcctca aaccctgttt gccgcctgtc agcatctgct ggcgatgttc
    23941 gttgcggtga tcacgccagc gctattaatc tgccaggcgc tgggtttacc ggcacaagac
    24001 acgcaacaca ttattagtat gtcgctgttt gcctccggtg tggcatcgat tattcaaatt
    24061 aaggcctggg gtccggttgg ctccgggctg ttgtctattc agggcaccag cttcaacttt
    24121 gttgccccgc tgattatggg cggtaccgcg ctgaaaaccg gtggtgctga tgttcctacc
    24181 atgatggcgg ctttgttcgg cacgttgatg ctggcaagtt gcaccgagat ggtgatctcc
    24241 cgcgttctgc atctggcgcg ccgcattatt acgccgctgg tttctggcgt tgtggtgatg
    24301 attatcggcc tgtcgctaat tcaggttggg ttaacgtcca ttggcggcgg ttacgcagcc
    24361 atgagcgata acaccttcgg cgcaccgaaa aatctgctgc tggcaggcgt ggtcttagcc
    24421 ttaattatcc tgcttaaccg tcaacgtaac ccttacttac gcgtggcctc actggtaatt
    24481 gcgatggcgg ccggatatgc gctggcgtgg tttatgggca tgttgccaga aagcaacgaa
    24541 cctatgacgc aagaactgat tatggtgcca acgccgctct attacggtct tggcattgaa
    24601 tggagtctgc tgctgccgct gatgctggtc tttatgatca cttcgctgga aaccattggc
    24661 gatatcacgg cgacctctga cgtttccgaa cagccagtgt ccggtccgct gtacatgaaa
    24721 cgcctgaaag gcggcgtgct ggcaaacggc ctgaactcgt ttgtttcggc ggtgtttaac
    24781 accttcccga actcctgctt cgggcaaaac aacggagtga tccagttgac tggtgttgcc
    24841 agccgctatg tcggttttgt cgtcgcgctg atgttgatcg tgctgggtct gttcccggca
    24901 gtgagcggtt ttgtacaaca cattccagaa ccggttctgg gcggcgcaac gcttgtaatg
    24961 tttggcacca tcgccgcctc cggtgtgcgt atcgtttctc gtgagccgct gaaccgtcgg
    25021 gcgattctga ttatcgcgct gtcgctggcg gttggtctgg gcgtgtctca gcagccgctg
    25081 attttgcagt ttgcccctga atggctgaaa aacctgctct cctccgggat cgccgcgggc
    25141 ggtattactg ccatcgtgct gaatctgatt ttcccaccag aaaaacagta attcactggc
    25201 ggcggtaaga taattaccgc cgcagtctca cctctttaac cattcccgcc ttgaggattg
    25261 cgcgtaaatc gtgcataact cccttatgtg catttcacgg gatggaagac catgaaattt
    25321 attgggaagc tgcttctcta cattctcatc gctctgttag tggcgatcgc tggcctctat
    25381 tttcttctgc aaacccgctg gggagcagaa catatcagcg catgggtttc cgagaatagc
    25441 gactatcatc tggccttcgg ggcgatggat caccgttttt ccgcgccatc tcatatcgtg
    25501 ctggagaacg tcacgtttgg tcgtgatggc cagcccgcga ccctggtggc caaaagtgtc
    25561 gacattgcgc taagcagtcg gcaactgacc gaaccacgcc atgtcgatac catcctgctg
    25621 gaaaacggga cgctgaatct caccgaccag accgcgccgc taccgttcaa agccgatcgt
    25681 ctgcaactgc gtgatatggc gtttaatagc ccgaatagcg aatggaaact gagcgcgcag
    25741 cgggtaaatg gcggcgtagt tccgtggtca ccaaaagccg gtaaagtgct aggtacgaag
    25801 gcgcagattc agtttagtgc cggatcgctt tcgctcaatg atgttcctgc caccaatgta
    25861 ctgattgaag gcagtattga taacgatcgc gttacgctga ctaacctggg tgccgacatc
    25921 gcccgcggga cattaaccgg aaacgcgcag cgtaacgccg acggcagctg gcaagtggaa
    25981 aacctgcgca tggcggatat acgtctacaa agcgaaaaat cgctaaccga cttctttgcg
    26041 ccattacgct ctgtcccgtc gttgcagatt ggtcgcctgg aagtgatcga tgctcgtttg
    26101 caaggtccgg actgggcggt gaccgacctc gatctcagct tgcgcaacat gaccttcagt
    26161 aaagatgact ggcagacaca ggaaggcaaa ctgtcgatga acgctagcga gttcatttat
    26221 ggttcgctgc atttatttga cccgattata aacacggaat tttccccgca gggcgtagcg
    26281 ctgcgccagt tcaccagccg ctgggaaggg ggtatggtca gaacgtcagg gaactggctg
    26341 cgtgacggga aaacgttgat ccttgatgat gcggcaattg ccgggctgga atataccttg
    26401 ccgaaaaact ggcaacagtt gtggatggaa acgacacccg gttggttaaa cagcctgcaa
    26461 ctgaagagat ttagcgccag ccgcaatctg atcattgata tcgaccctga cttcccgtgg
    26521 cagctcaccg cgctcgatgg ttacggtgcc aacctgacgc tggttaccga tcataaatgg
    26581 ggcgtctgga gtggctcggc gaatctgaat gccgccgccg cgacattcaa tcgtgttgat
    26641 gttcgtcgcc cgtcgctggc gctgaccgcc aacagcagca cggtgaatat cagcgaactg
    26701 agtgcattta ctgaaaaagg cattctggaa gccaccgcca gtgtttcaca aacgccacaa
    26761 cgtcagacac atatcagcct gaatggacgc ggtgtgccgg tgaatatttt gcaacagtgg
    26821 ggatggcctg aattaccgtt gactggcgac ggcaatattc agcttaccgc cagtggcgat
    26881 attcaggcca atgtcccgtt gaaacctacg gttagcgggc aattgcatgc cgtgaacgcc
    26941 gcaaagcagc aagtgactca aaccatgaat gctggcatcg tttccagcgg tgaagttaca
    27001 tcgacggagc cggtgcggta aacatcaatc tcgccgggta cgactcagac gtacccggca
    27061 ttccatcaat agattacaac gtaattgtca gcgcattccc ttgaggcttc accaccagcc
    27121 cctgctcact ttcagcctgc gaaccgtctt gcagaccatt tactttcaca acattgcgca
    27181 ggcacagtgt ccagttcttc gcctcgcccg caccagtcac agtaatcgtg ttgccagtac
    27241 gtgctgcttt taaagtaaag atcaccgatc cgtcagcagc gggcacttca cagacggctt
    27301 catgcccgtc ttgcagatta aagaggtgga atgccgtgcc ttcgtgccac acgtaatcgg
    27361 gacgttgatc gttgttgtcc agcgccagta gagtgttatc acgcacataa acgggcagac
    27421 tcaggaagcc gtgctgctgt ttatgccagc gactaccgtc gagttcatcg ttgtgccaca
    27481 ggtgtgtcca gcgaccttcc ggcaggtaga actgcacatc gcccgcttca gtgaacaccg
    27541 gcgcaaccat cacgttgtca cctaacatgt attgacggtc aaggtaatca caagccggat
    27601 cgtccgggaa ctccatcatc atggcccgca tcatcggcgt accccgcgcg ttcgcacgcg
    27661 cagcttcacg atacagatac ggcatcatgc ggcatttcag ttgcgtgaag aagcgcacca
    27721 catcacagga ctcatcatcg taggcccacg gcacacgata agatttgcta ccgtgtaaac
    27781 ggctatggct ggagagcaaa ccaaacgcgc accagcgttt gtaaacgtgc gccggagcgg
    27841 tattttcaaa gccgccgata tcgtggctcc agaagccaaa acctgaaagg ccaatagaca
    27901 aaccaccgcg caggctttcc gccattgatt cgtagttagc gtaacaatcg ccaccccagt
    27961 gtaccgggaa tttctgcgca ccgacggagg ccgagcgggc aaacaagaca gcttcttcct
    28021 caccaacggt gtccttgagc acgttccaca ccagttcgtt gtagatgtac gcataatggt
    28081 tatgcatttt ctgcggatcg gaaccgtcaa accactgaac atcagttggg atacgttcgc
    28141 caaagtcggt cttaaagcaa tcaacgccca tcgcgaccag acctttcagt ttgtcggcgt
    28201 accatttgca ggcatccgga ttggtaaagt cataaatcgc cagacctggc tgccatttat
    28261 cccactgcca tagcgaaccg tccgggcgtt tgagtaaata gcctttctct tgtaactctt
    28321 taaagacggg ggatttttga ccgatatagg ggttaatcca gacgcagatt ttcagtcctt
    28381 tcgctttcag gcggcggatc atcccttccg ggtcagggaa agtcagcggg tcccactcaa
    28441 aatcgcacca ctggaaggct ttcatccaga aacagtcaaa gtggaaaaca tgcagcggca
    28501 gattgcgttc cgccatacca tcgataaagc tgtttaccgt cgcttcgtcg tagttggtgg
    28561 taaatgaagt ggttagccac aggccgaagg accacgcggg cggcagcgcc ggacgaccag
    28621 taaagcgggt ataacgatca agtaccgctt tcggcgtcgg gccgtcgata acaaagtatt
    28681 cgagatattc actctcaacg ctgaactgca ctttggagac tttctccgat cccacttcaa
    28741 aagagacaca ctggggatga ttgaccagta ccccataacc acggttagtc atgtagaacg
    28801 ggatattttt atacgcctgt tcagtacttg tgccgccgtc ccggttccag gtctctaccg
    28861 tctggccatt gcgcaccagg gcagtaaagc gctctcccag accgtaaact gtttcgccaa
    28921 cgccaagatc aagccgctca aacatataat tgcgttgatt attcgtgtcc tgcacgtagc
    28981 cattattttt cacctgacta ccggtaatac gttcgccgtt gcgcagaaaa tccagtgacc
    29041 agaactcacc tttgctgaca cgcgcgctta agttgccact tttaaactca gcataacgtt
    29101 ctgtgttttc gattgtgacc ttcacgtcct gcaaaatatt gagcggataa tgaggaccgt
    29161 tattcagcgc cccctgaaaa tgctcaatcc gcacaccgac aataccttcc tgtggggaga
    29221 aaaagcgcaa cgtaaataaa ggcgtatcaa gctgccaggt acgttcacgc acatcacggg
    29281 gggcagcata gaccaccatt tcattatcct gctgttcaac ctcgaacacc tgaagcgggt
    29341 gaatcaaatt gaggccaggt tgaatcaacc agtttccatc gctaattttc attgccgttc
    29401 cttagttctg cacttcttga gaggtgaatt gttgctggca acggcgttta ccctgagcca
    29461 gctgttccat aacggttttc agattgtgcg tcgtgagtga gtagtagcgt ttagcgataa
    29521 tcgcgctcag caaataacag atcgccggaa caatcgtgaa tagcgcaata atgatgctaa
    29581 tcgtggcgct gttctgcgct ttttctgccg catcatatcc gccataagcc agcatccagc
    29641 cgataagagc gccgccgaag gccaacccca gtttgagcac aaacagcgtg ccagcaaaac
    29701 tgatcccggt caggcgttta ccattgcacc actcgccgta gtcgacggta tcggacatca
    29761 ttacccactg gataggtgtc accagttgat gcaacacacc aatcacgaag atgaagacaa
    29821 acatagtgat gctggcctgc atgggaacaa agaacatcgc gaggctaatc actgccagca
    29881 gggcgttcgt ccaccagaag atagtgactt tacatttcca gtcggtcaga ggttttgcca
    29941 gtgcggaacc aatcaggtta cccacgcaat aagtggtgag aaaagcgaca aacacttccg
    30001 gcgtgcccaa aatccatgtg acgtaataca tcatcgcccc accgcgtacg cacaccgcca
    30061 ggatattgaa aatggttagt aaaccgacaa tccgccactg gtcgttttgc cagatatcac
    30121 gtaaatcttc ccgcatagac gttgttgtag gtggtgcttc aacgcgttct ttagtggtga
    30181 agaaacaaaa tgccagcatc atgaatgcca ccacggaaag gaccgcgata ccgccctgga
    30241 aaccgagtgg tttattatca ccgccaatta aattaaccag tggcatcatc agaacagtag
    30301 aaagcatgcc tcccgcggtc gccagcacaa aacgccagga ttgcagcgag atacgctgag
    30361 tcgggtcatt ggtgattaca ccacccaatg cgcagtaagg gatattgacg acggtataaa
    30421 gtaaggtaag tagggtgtaa gtaattgctg catagatcat tttgccgttc atactgagat
    30481 ctggcgtgct ataggccagt acacagacga tcccgaatgg cagtgcgcca aacagtaccc
    30541 acggacgaaa tttaccccag cgagagcgcg ttcgatcggc caacaacccc atgcaaggat
    30601 cggaaatcgc atccagtgca cgagcgacca aaaacatggt tccgacaaaa ccggcaggaa
    30661 tgccaaaaat atcggtataa aagaacatca tatataacat tacgttatcg aaaataatgt
    30721 ggctggcggc gtctcccatg ccataaccaa ttttctcttt aacggacaac acttcactct
    30781 tcatctgctt ttccttgatg ctataggggt gctgagaccg ataacgcatt ttgtaaacca
    30841 tccctgtgag agcgaatatt ccgatatctg gttattaatt tatgattctt gttttatgtg
    30901 atcgtggtag
//
LOCUS       DAPHKZ010000049        30029 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.049, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000049 DAPHKZ010000000
VERSION     DAPHKZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30029
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.049"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(39..1493)
                     /gene="xylB"
                     /locus_tag="RH288_002295"
     CDS             complement(39..1493)
                     /gene="xylB"
                     /locus_tag="RH288_002295"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDV4031343.1"
                     /translation="MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQD
                     PEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCA
                     QECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
                     TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAK
                     AWGMATVPVVAGGGDNAAGAVGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHS
                     FCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQADESAEPVWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTL
                     IGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLP
                     LEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA"
     gene            complement(1565..2887)
                     /gene="xylA"
                     /locus_tag="RH288_002296"
     CDS             complement(1565..2887)
                     /gene="xylA"
                     /locus_tag="RH288_002296"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDV4031344.1"
                     /translation="MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHD
                     VDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVE
                     HKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAG
                     HSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNS
                     ELGQQILKGQMSLADLAKYAQEHHLSPVHQSGRQEQLENLVNHYLFDK"
     gene            3253..4245
                     /gene="xylF"
                     /locus_tag="RH288_002297"
     CDS             3253..4245
                     /gene="xylF"
                     /locus_tag="RH288_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV4031345.1"
                     /translation="MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDR
                     DIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA
                     KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
                     AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS
                     NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAE
                     IAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDGFHKESEL"
     gene            4323..5864
                     /gene="xylG"
                     /locus_tag="RH288_002298"
     CDS             4323..5864
                     /gene="xylG"
                     /locus_tag="RH288_002298"
                     /EC_number="7.5.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HDV4031346.1"
                     /translation="MPYLLEMKNITKTFGSVKAIDNVCLRLNAGEIVSLCGENGSGKS
                     TLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENI
                     FLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
                     VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDG
                     QHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKR
                     VNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQA
                     IAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQL
                     KVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQ
                     LVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHV
                     EKQSV"
     gene            5842..7023
                     /gene="xylH"
                     /locus_tag="RH288_002299"
     CDS             5842..7023
                     /gene="xylH"
                     /locus_tag="RH288_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose ABC transporter permease XylH"
                     /protein_id="HDV4031347.1"
                     /translation="MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFT
                     WTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICD
                     VWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
                     TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVV
                     GRQALTAIIVLGAIWLLNDYRGVPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLE
                     AARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGG
                     TSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRR
                     S"
     gene            7101..8279
                     /gene="xylR"
                     /locus_tag="RH288_002300"
     CDS             7101..8279
                     /gene="xylR"
                     /locus_tag="RH288_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XylR"
                     /protein_id="HDV4031348.1"
                     /translation="MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATD
                     NYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRS
                     TDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMI
                     HAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
                     "
     gene            complement(8475..9299)
                     /locus_tag="RH288_002301"
     CDS             complement(8475..9299)
                     /locus_tag="RH288_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HDV4031349.1"
                     /translation="MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKAS
                     NKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITAERNWL
                     ISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM"
     gene            9619..11649
                     /gene="malS"
                     /locus_tag="RH288_002302"
     CDS             9619..11649
                     /gene="malS"
                     /locus_tag="RH288_002302"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HDV4031350.1"
                     /translation="MKLAACFLTLLPGFAVAASWTSPGFPAFSEQGTGTFVSHAQLPK
                     GTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPPQWRLFRDGEYTLQIDTRSGTPT
                     LMISIQNAAEPVASLVRECPKWDGLPLTVDVSATFPEGAAVRDYYSQQIAIVKNGQIM
                     LQPAATSNGLLLLERAETDTSAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMA
                     EIGTFHGGDLRGLTNKLDYLQQLGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYY
                     TQDWTNLDANMGNEADLRTLVDSAHQRGIRILFDVVMNHTGYATLADMQEYQFGALYL
                     SGDEVKKSLGERWSDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNP
                     GFDDLTMSLAFLPDIKTESTTASGLPVFYKNKMDTHAKAIDGYTPRDYLTHWLSQWVR
                     DYGIDGFRVDTAKHVELPAWQQLKTEASAALREWKKANPDKALDDKPFWMTGEAWGHG
                     VMQSDYYRHGFDAMINFDYQEQAAKAVDCLAQMDTTWQQMAEKLQGFNVLSYLSSHDT
                     RLFREGGDKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSA
                     ASVAHWQKISQFRARHPAIGAGKQTTLLLKQGYGFVREHGDDKVLVVWAGQQ"
     gene            11827..13080
                     /gene="avtA"
                     /locus_tag="RH288_002303"
     CDS             11827..13080
                     /gene="avtA"
                     /locus_tag="RH288_002303"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HDV4031351.1"
                     /translation="MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIP
                     EMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIAL
                     TNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGI
                     ISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPENRCLIHK
                     PEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
                     PEPEKIEAGVKILAEEIERAWAESH"
     gene            complement(13231..13704)
                     /locus_tag="RH288_002304"
     CDS             complement(13231..13704)
                     /locus_tag="RH288_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDV4031352.1"
                     /translation="MNRFIIADATKCIGCRTCEVACAVSHHENQDCAALSPDEFISRI
                     RVIKDHCWTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQTRCIGCKSCMLACPFG
                     AMEVVSSRKKARAIKCDLCWHRETGPACVEACPTKALQCMDVEKVQRHRLRQQPV"
     gene            complement(13806..14654)
                     /gene="yiaJ"
                     /locus_tag="RH288_002305"
     CDS             complement(13806..14654)
                     /gene="yiaJ"
                     /locus_tag="RH288_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HDV4031353.1"
                     /translation="MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCP
                     LAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIH
                     IAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMG
                     KIYMAFGHPDYVKSYWESHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL
                     GVSCIAVPVFDIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRD
                     DLGAIT"
     gene            14855..15853
                     /gene="yiaK"
                     /locus_tag="RH288_002306"
     CDS             14855..15853
                     /gene="yiaK"
                     /locus_tag="RH288_002306"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HDV4031354.1"
                     /translation="MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAA
                     DHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRI
                     LPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPT
                     RDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL"
     gene            15865..16332
                     /locus_tag="RH288_002307"
     CDS             15865..16332
                     /locus_tag="RH288_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDV4031355.1"
                     /translation="MIFGHIAQPNPCRLPAAIEKALDFLRATDFNALEPGVVEIDGKN
                     IYTQIIDLTTREAVVNRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRNI
                     IFYHDSEHESFIEMIPGSYAIFFPQDVHRPGCIMQTASEIRKIVVKVALTALN"
     gene            16450..16923
                     /gene="yiaM"
                     /locus_tag="RH288_002308"
     CDS             16450..16923
                     /gene="yiaM"
                     /locus_tag="RH288_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HDV4031356.1"
                     /translation="MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYL
                     FVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLK
                     TIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA"
     gene            16926..18203
                     /gene="yiaN"
                     /locus_tag="RH288_002309"
     CDS             16926..18203
                     /gene="yiaN"
                     /locus_tag="RH288_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HDV4031357.1"
                     /translation="MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLDMFDVQIMA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAM
                     IMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFG
                     VSSRLSISKLFMAGIAPGMMMGATLMLTWWWQASRLNLPRQQKATMQEIWHSFVSGIW
                     ALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTS
                     VVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTP
                     TVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDA
                     VRGVFPYVLVLYSLLVVFVFIPDLIILPLKWIN"
     gene            18216..19202
                     /gene="yiaO"
                     /locus_tag="RH288_002310"
     CDS             18216..19202
                     /gene="yiaO"
                     /locus_tag="RH288_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter
                     substrate-binding protein YiaO"
                     /protein_id="HDV4031358.1"
                     /translation="MKLRSVTYALFIAGLAAFSTSSLAAQSLRFGYETSQTDSQHIAA
                     KKFNDLLQERTKGELKLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFAGLSPVMN
                     LLDVPFLFRDTAHAHKTLDGKVGDDLKASLEGKGLKVLAYWENGWRDVTNSRAPVKTP
                     ADLKGLKIRTNNSPMNIAAFKVFGANPIPMPFAEVYTGLETRTIDAQEHPINVVWSAK
                     FFEVQKFLSLTHHAYSPLLVVINKAKFDGLSPEFQQALVSSAQEAGNYQRKLVAEDQQ
                     KIIDGMKEAGVEVITDLDRKAFSDALGNQVRDMFVKDVPQGADLLKAVDEVQ"
     gene            19206..20702
                     /gene="lyxK"
                     /locus_tag="RH288_002311"
     CDS             19206..20702
                     /gene="lyxK"
                     /locus_tag="RH288_002311"
                     /EC_number="2.7.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulokinase"
                     /protein_id="HDV4031359.1"
                     /translation="MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWA
                     ERDMAELWQYCMAVIRALLTHSGVSGEQIVGIGISAQGKGLFLLDKNDKPLGNAILSS
                     DRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHEPERYAQIGCVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMSLGEYDPCLTDWLGIAEINHALPPVVGSAEIC
                     GEITAQTAALTGLKAGTPVVGGLFDVVSTALCAGIEDEFTLNAVMGTWAVTSGITRGL
                     RDGEAHPYVYGRYVNDGEFIVHEASPTSSGNLEWFTAQWGEISFDEINQAVASLPKAG
                     GDLFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGVVFSHMTHLNRMRERFT
                     DVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTGVYHNFSE
                     AQRDLRHPVRTLLPDMTAHQLYQKKYQRYQHLIAALQGFHARIKEHTL"
     gene            20699..21361
                     /gene="ulaD"
                     /locus_tag="RH288_002312"
     CDS             20699..21361
                     /gene="ulaD"
                     /locus_tag="RH288_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDV4031360.1"
                     /translation="MSRPLLQLALDHSSLEAAQRDVTLLKDSVDIVEAGTILCLNEGL
                     GAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMA
                     QRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFKDIRVKAFIAGRALAGAANPAQVAGDFHAQIDAIWGGA
                     RA"
     gene            21354..22214
                     /locus_tag="RH288_002313"
     CDS             21354..22214
                     /locus_tag="RH288_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDV4031361.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLDWSAAQRTSLVAAMIETGVGIPSMCLSAHRRFPFGSRDEAVRERAREIMSKAIR
                     LARDLGIRTIQLAGYDVYYEDHDEGTRQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
                     NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTE
                     QSPGQFRDVPFGEGCVDFVGIFKTLHKLNYRGSFLIEMWTEKAKEPVLEIIQARRWIE
                     ARMQEAGFIC"
     gene            22208..22903
                     /gene="araD"
                     /locus_tag="RH288_002314"
     CDS             22208..22903
                     /gene="araD"
                     /locus_tag="RH288_002314"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDV4031362.1"
                     /translation="MLEQLKADVLAANLALPAHHLVTFTWGNVSAVDDTRQWMVIKPS
                     GVEYDVMTADDMVVVEIASGKAVEGSKKPSSDTPTHLALYRRYAEIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRQMTTEEINGEYEYQTGEVIIKTFEERGLNP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKH
                     YLRKHGDNAYYGQ"
     gene            complement(22935..23036)
                     /locus_tag="RH288_002315"
                     /pseudo
     CDS             complement(22935..23036)
                     /locus_tag="RH288_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            complement(23250..23990)
                     /locus_tag="RH288_002316"
     CDS             complement(23250..23990)
                     /locus_tag="RH288_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MipA/OmpV family protein"
                     /protein_id="HDV4031363.1"
                     /translation="MLINRNIVALFALPFMASATASELSIGAGAAYNESPYRGYNENT
                     KAIPLISYEGDSFYVRQTTLGFILSQSEKNELSLTASWMPLEFDPADNDDYAMQQLDK
                     RDSTAMAGVAWYHHERWGTVKASAAADVLDNSNGWVGELSVFHKMQIGRLSLTPALGV
                     LYYDENFSDYYYGISESESRRSGLASYSAQDAWVPYVSLTAKYPIGEHVVLMASAGYS
                     ELPEEITDSPMIDRNESFTFVTGVSWRF"
     gene            24114..25088
                     /locus_tag="RH288_002317"
     CDS             24114..25088
                     /locus_tag="RH288_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4031364.1"
                     /translation="MTKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADF
                     ESKVGLKVFDRTTRQLMLTPFGTALLPYINDMLDRNEQLNNFIADYKHEKRGRVTIYA
                     PTGIITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDE
                     SLVASFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGS
                     KEVRDYRVKGNYVCDNTQSALELARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWW
                     LDLVAIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAAESED"
     gene            complement(25085..26221)
                     /locus_tag="RH288_002318"
     CDS             complement(25085..26221)
                     /locus_tag="RH288_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDV4031365.1"
                     /translation="MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLI
                     LLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDKKNTLIKKGEVLFRLDPTRYQAR
                     VDRLMADIVTAEHKQRALGAELDEMAANTQQAKATRDKFAKEYQRYARGSQAKVNPFS
                     ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLE
                     QTIVRAPSDGYVTQVLIRPGTYAASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGD
                     DAEVVFNALPGKVFSGKLAAISPTVPGGAYQSTGTLQTLNTAPGSDGVIATIELDEHT
                     DLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH"
     gene            complement(26227..26550)
                     /locus_tag="RH288_002319"
     CDS             complement(26227..26550)
                     /locus_tag="RH288_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HDV4031366.1"
                     /translation="MFLDYFALGVLIFVFLVIFYGIIILHDIPYLIAKKRNHPHADAI
                     HVAGWVSLFTLHVIWPFLWIWATLYRPERGWGMQSHDSSVMQLQQRIAGLEKQLADIK
                     SSSAE"
     gene            26733..26876
                     /locus_tag="RH288_002320"
     CDS             26733..26876
                     /locus_tag="RH288_002320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031367.1"
                     /translation="MNNSSKTSTVQIKRIKPSIIYRLLLIGLGSPMVIYGLVRPLTIE
                     TRD"
     gene            complement(27095..28633)
                     /gene="aldB"
                     /locus_tag="RH288_002321"
     CDS             complement(27095..28633)
                     /gene="aldB"
                     /locus_tag="RH288_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HDV4031368.1"
                     /translation="MTNNPPSVQIKPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQN
                     LTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGV
                     VNVVNGAGGVIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLE
                     PTILFGQNNMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(28798..29949)
                     /gene="yiaY"
                     /locus_tag="RH288_002322"
     CDS             complement(28798..29949)
                     /gene="yiaY"
                     /locus_tag="RH288_002322"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine dehydrogenase"
                     /protein_id="HDV4031369.1"
                     /translation="MASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDNMLTK
                     LGMAGDVQKALEERNIFSVIYDGTQPNPITENVAAGLKLLKENNCDSVISLGGGSPHD
                     CAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
                     MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALK
                     AVTMIAENLPLAVEDGSNAKAREAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLP
                     HGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAEACINAIRELAKKV
                     DIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM"
BASE COUNT         7443 a         7754 c         7507 g         7325 t
ORIGIN      
        1 gtgaattatc ccccacccgg tcaggcaggg gataacgttt acgccattaa tggcagaagt
       61 tgctgataga ggcgacggaa cgtttctcgt cgtggctgat aagcggcata acgctgcgca
      121 tctggtagat gcgactgttc taacggtagt tgcggcaaca attcaatgag cgatttctct
      181 ggattcgccg cgatctgcgc cagccttgct gcgcccagtg ctggccccac atcccccccc
      241 gtacggtaat cgagctgctg accgctgata tccgccagca tctgacgcca gtactcacta
      301 cgcgccccgc ccccaatcaa cgtaacactt tgcggtttaa taccgcaggc atgcacgaca
      361 tccatgccat ctgccagcgc ataacccacg ccttccagca ctgctcgcgc cagttcattg
      421 gggccatgtt gatgagtcaa accaaagaaa acccccttcg cctggggatt attgtgtggc
      481 gtacgctcgc cggaaagata aggcagaaac caaactggct cggcactttc atcagcctgt
      541 tgagctgcag cgattaaagc tgggacattg ctcaggccgg ttaatttcgc ggcccaatcc
      601 agacacgacg ctgcactcag catcacagac attaaatgcc aacgttgcgg tagcgcatgg
      661 caaaagctat gtacggcgct ttctggcttg cttaagaacc cttcgctgac agcaaaatag
      721 acccccgacg tccccagcga taacattgcc tgattagcat caaccattcc cacaccaact
      781 gcaccagctg cattgtcgcc accgcctgcg acaactggca ccgtcgccat accccacgct
      841 ttcgcaactt caggtaacaa agcaccagta atttcgctgc cttcgtataa tgcgggcatc
      901 tggtcacgag ataagtcgca agcctgcagc atgacgtcac tccagtcacg ctttgcgaca
      961 tccagccaca tggtgccagc tgcgtcagac atatcgctgg caaactcccc cgtcatacgc
     1021 agacgcaagt aatctttcgg taataatact ttgtcgattt gacggaatat ctccggctca
     1081 tgccgctgaa cccatagcaa tttaggcgca gtaaatccgg gcatcatcag gttgccggta
     1141 atcacccgcg attgcggaac tcgcgcttcc agcaaagtgc actcttgcgc acagcgcccg
     1201 tcgttccaca aaatggcagg gcgtaacacc cgttgctgag catccagcaa ggttgctccg
     1261 tgcatctggc cggcaatacc caatgcttta acgtcctgca gagaatgctg atcgcccaga
     1321 gctttcattg cgcgatcagt tgcctgccac cactgttccg ggtcttgttc cgaccagagt
     1381 ggatgcgggc gcgaaacggt cagcttttcc gtttgcgcag caaccacctc accctgctcg
     1441 ttgagcaaaa taacttttac gcccgaggtg ccaagatcta tcccgatata catatcgatc
     1501 gttccttaaa aaaatgcccg gtatcgctac cgataaccgg gccaacggac tgcacagtta
     1561 gccgttattt gtcgaacaga taatggttta ccagattttc cagttgttcc tggcgaccac
     1621 tctgatgcac cggagacaaa tgatgttcct gagcatattt ggctaaatct gccagtgaca
     1681 tttggccttt caggatttgc tggcccaatt cgctattcca gccggaataa cgctgcgcga
     1741 tgcgtttatc cagctcgcca tcttcaatca tgcgcgctgc aattttcagc gccagtgcca
     1801 tcgtatccat cgcgccgata tgaccgtaaa acagatcata tttatcagta ctttgacgac
     1861 gtactttggc atcgaagttc agaccaccgg tggtgaaacc gcctgctttg agaatttcat
     1921 acatcaccag cgcattctct tccacactgt tcgggaactg gtcggtgtcc cagcccagtt
     1981 gcgcatcgcc acggttggcg tcgacagaac cgaacaggcc aagcgcaatg gcggtggcta
     2041 tttcatgatg gaaagagtga cctgccagcg tcgcgtggtt agcttcaatg ttcagtttaa
     2101 tctctttttc cagaccaaac tgtttcagga agccatagac cgtcgcggca tcgtaatcat
     2161 attgatgttt ggtcggttct tgcggtttcg gttcgataag caacgtgccc tggaaaccga
     2221 ttttatgttt atgctcaacc accatctgca taaagcggcc cagttgttca cgctcctgac
     2281 gcaagtcggt atttaacagc gtttcgtaac cttcacgacc gccccacagg acatagtttt
     2341 caccgcccaa tttatgggtt gcttccatcg ctgtaacaac ttgcgttgcc gcccagctga
     2401 agacttcagg atctgggttc gtcgccgcac ccgcgccgta gcgagggttt gtaaagcagt
     2461 tggcggttcc ccacagcagc ttcacgccgc tctcttcttg cttgcctgcc aggacatcaa
     2521 ccatttgcgc aaaattattg atgtactctt ttaacgacgc gccctcaggg gaaacatcca
     2581 catcgtggaa gcaataaaat ggcacatgta acttgtggaa aaactcaaat gcgacatctg
     2641 ctttacgctt cgccaacgcc agtgcctcac caggctgctg ccacggacga ttaaacgccc
     2701 ccacaccaaa catatccgcc ccgttccagc agaaggtgtg ccagtagcag gcggcaaaac
     2761 gcaagtgctc ttccatacgc ttacccaaca ccagttcgtc gggattgtag tgacggaatg
     2821 ctaacgggtt tgaggatttt gagccttcat aacgaacgcg atcgagctgg tcaaaatagg
     2881 cttgcatatt gaactccata atcaggtaat gccgcgggtg atggatgatg tcgtaatatt
     2941 gggcactccc tttcagttgc tcaattatgt tatttcacac tgctattgag ataattcaca
     3001 agtgtgcgct cgctcgcaaa ataaaatgga atgatgaaac tgggtaattc ctcgaagaga
     3061 aaaatgcaat aagtacaatt gcgcaacaaa agtaagatct cggtcataaa tcaagaaata
     3121 aaccaaaaat cgtaatcgaa agataaaaat ctgtaattgt tttcccctgt ttagttgcta
     3181 aaaattggtt acgtttatcg cggtgattgt tacttattaa aactgtcctc taactacaga
     3241 aggccctaca ccatgaaaat aaagaacatt ctactcaccc tttgcacctc actcctgctt
     3301 accaacgttg ctgcacacgc caaagaagtc aaaataggta tggcgattga tgatctccgt
     3361 cttgaacgct ggcaaaaaga tcgagatatc tttgtgaaaa aggcagaatc tctcggcgcg
     3421 aaagtatttg tacagtctgc aaatggcaat gaagaaacac aaatgtcgca gattgaaaac
     3481 atgataaacc ggggtgtcga tgttcttgtc attattccgt ataacggtca ggtattaagt
     3541 aacgttgtaa aagaagccaa acaagaaggc attaaagtat tagcttacga ccgtatgatt
     3601 aacgatgcgg atatcgattt ttatatttct ttcgataacg aaaaagtcgg tgaactgcag
     3661 gcaaaagccc tggtcgatat tgttccgcaa ggtaattact tcctgatggg cggctcgccg
     3721 gtagataaca acgccaagct gttccgcgcc ggacaaatga aagtgttaaa accttacgtt
     3781 gattccggaa aaattaaagt cgttggtgac caatgggttg atggctggtt accggaaaac
     3841 gcattgaaaa ttatggaaaa cgcgctaacc gccaataata acaaaattga tgctgtagtt
     3901 gcctcaaacg atgccaccgc aggtggggca attcaggcat taagcgcgca aggtttatca
     3961 gggaaagtag caatctccgg ccaggatgcg gatctcgcag gtattaaacg tattgctgcc
     4021 ggtacgcaaa ctatgacggt gtataaacct attacgttgt tggcaaatac tgccgcagaa
     4081 atagccgttg agttgggcaa tggtcaggaa ccaaaagcag ataccacact gaataatggc
     4141 ctgaaagatg tcccctcccg cctcctgaca ccgatcgatg tgaataaaaa caacatcaaa
     4201 gatacggtaa ttaaagacgg attccacaaa gagagcgagc tgtaagcgtt acgccccagc
     4261 gcggagcggg ggcgtgattt ctctccatgc cgcgtgaatg aattggctta ggtggagtcg
     4321 ttatgcctta tctacttgaa atgaagaaca ttaccaaaac cttcggcagt gtgaaggcga
     4381 ttgataacgt ctgcttgcgg ttgaatgctg gcgaaatcgt ctcactttgt ggggaaaatg
     4441 ggtctggtaa atcaacgctg atgaaagtgc tgtgtggtat ttatccccat ggctcctacg
     4501 aaggcgaaat tatttttgcg ggagaagaga ttcaggcgag tcacatccgc gataccgaac
     4561 gcaaaggtat cgccatcatt catcaggaat tggccctggt gaaagaattg accgtgctgg
     4621 aaaatatctt cctgggtaac gaaataaccc acaatggcat tatggattat gacctgatga
     4681 cgctacgctg tcagaagctg ctcgcacagg tcagtttatc catttcacct gatacccgcg
     4741 ttggcgattt agggcttggg caacaacaac tggttgaaat tgccaaggca cttaataaac
     4801 aggtgcgctt gttaattctc gatgaaccga cagcctcatt aactgagcag gaaacgtcgg
     4861 ttttactgga tattattcgc gatctacaac agcacggtat cgcctgtatt tatatttcgc
     4921 acaaactcaa cgaagtcaaa gcgatttccg atacgatttg cgttattcgc gacggacagc
     4981 acattggtac gcgtgatgct gccggaatga gtgaagacga tattatcacc atgatggtcg
     5041 ggcgagagtt aaccgcgctt taccctaatg aaccacatac caccggagat gaaatattac
     5101 gtattgaaca tctgacggca tggcatccgg ttaatcgtca tattaaacga gttaatgatg
     5161 tctcgttttc cctgaaacgt ggcgaaatat tgggtattgc cggactcgtt ggtgccggac
     5221 gtaccgagac cattcagtgc ctgtttggtg tgtggcccgg acaatgggaa ggaaaaattt
     5281 atattgatgg caaacaggta gatattcgta actgtcagca agccatcgcc caggggattg
     5341 cgatggtccc cgaagacaga aagcgcgacg gcatcgttcc ggtaatggcg gttggtaaaa
     5401 atattaccct cgccgcactc aataaattta ccggtggcat tagccagctt gatgacgcgg
     5461 cagagcaaaa atgtattctg gaatcaatcc agcaactcaa agttaaaacg tcgtcccccg
     5521 accttgctat tggacgtttg agcggcggca atcagcaaaa agcgatcctc gctcgctgtc
     5581 tgttacttaa cccgcgcatt ctcattcttg atgaacccac caggggtatc gatattggcg
     5641 cgaaatacga gatctacaaa ttaattaacc aactcgtcca gcagggtatt gccgttattg
     5701 tcatctcttc cgaattacct gaagtgctcg gccttagcga tcgtgtactg gtgatgcatg
     5761 aagggaaact aaaagccaac ctgataaatc ataacctgac tcaggagcag gtgatggaag
     5821 ccgcattgag gagcgaacat catgtcgaaa agcaatccgt ctgaagtgaa attggccgta
     5881 ccgacatccg gtggcttctc cgggctgaaa tcactgaatt tgcaggtctt cgtgatgatt
     5941 gcagctatca tcgcaatcat gctgttcttt acctggacca ccgatggtgc ctacttaagc
     6001 gcccgtaacg tctccaacct gttacgccag accgcgatta ccggcatcct cgcggtagga
     6061 atggtgttcg tcataatttc tgctgaaatc gacctttccg tcggctcaat gatggggctg
     6121 ttaggtggcg tcgcggcgat ttgtgacgtc tggttaggct ggcctttgcc acttaccatc
     6181 attgtgacgc tggttctggg actgcttctc ggtgcctgga acggatggtg ggtcgcgtac
     6241 cgtaaagtcc cttcatttat tgtcaccctc gcgggcatgt tggcatttcg cggcatactc
     6301 attggcatca ccaacggcac gactgtatcc cccaccagcg ccgcgatgtc acaaattggg
     6361 caaagctatc tccccgccag taccggcttc atcattggcg cgcttggctt aatggctttt
     6421 gttggttggc aatggcgcgg aagaatgcgc cgtcaggctt tgggtttaca gtctccggcc
     6481 tctaccgcag tagtcggtcg ccaggcttta accgctatca tcgtattagg cgcaatctgg
     6541 ctgttgaatg attaccgtgg cgttcccact cctgttctgc tgctgacgtt gctgttactc
     6601 ggcggaatgt ttatggcaac gcggacggca tttggacgac gcatttatgc catcggcggc
     6661 aatctggaag cagcacgtct ctccgggatt aacgttgaac gcaccaaact tgccgtgttc
     6721 gcgattaacg gattaatggt agccatcgcc ggattaatcc ttagttctcg acttggcgct
     6781 ggttcacctt ctgcgggaaa tatcgccgaa ctggacgcaa ttgcagcatg cgtgattggc
     6841 ggcaccagcc tggctggcgg tgtgggaagc gttgccggag cagtaatggg ggcatttatc
     6901 atggcttcac tggataacgg catgagtatg atggatgtac cgaccttctg gcagtatatc
     6961 gttaaaggtg cgattctgtt gctggcagta tggatggact ccgcaaccaa acgccgttct
     7021 tgattttgat aaaaattttc tcaaagccgg ttacgtatta ccggttttga gtttttgcat
     7081 gattcagcag gaaaagaacc atgtttacta aacgtcaccg catcacatta ctgttcaatg
     7141 ccaataaagc ctatgaccgg caggtagtag aaggcgtagg ggaatattta caggcgtcac
     7201 aatcggaatg ggatattttc attgaagaag atttccgcgc ccgcattgat aaaatcaagg
     7261 actggttagg agatggcgtc attgccgact tcgacgacaa acagatcgag caagcgctgg
     7321 ctgatgtcga cgtccccatt gttggggttg gcggctcgta tcaccttgca gaaagttacc
     7381 cacccgttca ttacattgcc accgataact atgcgctggt tgaaagcgca tttttgcatt
     7441 taaaagagaa aggcgttaac cgctttgctt tttatggtct tccggaatca agcggcaaac
     7501 gttgggccac tgagcgcgaa tatgcatttc gtcagcttgt cgccgaagaa aagtatcgcg
     7561 gagtggttta tcaggggtta gaaaccgcgc cagagaactg gcaacacgcg caaaatcggc
     7621 tggcagactg gctacaaacg ctaccaccgc aaaccgggat tattgccgtt actgacgccc
     7681 gagcgcggca tattctgcaa gtatgtgaac atctacatat tcccgtaccg gaaaaattat
     7741 gcgtgattgg catcgataac gaagaactga cccgctatct gtcgcgtgtc gccctttctt
     7801 cggtcgctca gggcgcgcgg caaatgggct atcaggcggc aaaactgttg catcgattat
     7861 tagataaaga agaaatgccg ctacagcgaa ttttggtccc accagttcgc gtcattgaac
     7921 ggcgctcaac agattatcgc tcgctgaccg atcccgccgt tattcaggcc atgcattaca
     7981 ttcgtaatca cgcctgtaaa gggattaaag tggatcaggt actggatgcg gtcgggatct
     8041 cgcgctccaa tcttgagaag cgttttaaag aagaggtggg tgaaaccatc catgccatga
     8101 ttcatgccga gaagctggag aaagcgcgca gtctgctgat ttcaaccacc ttgtcgatca
     8161 atgagatatc gcaaatgtgc ggttatccat cgctgcaata tttctactct gtttttaaaa
     8221 aagcatatga cacgacgcca aaagagtatc gcgatgtaaa tagcgaggtc atgttgtagc
     8281 gatgatgaga attgtcggcg tcacatcagg taacgctgcg tggttgtcgg atgcggcgtg
     8341 aacgccttat ccgacctacc cgccaggcat gataaaacgc accaacaacg cttcaggctc
     8401 gtagctcaac tgcctgagac aaagtaaaaa gccttatccg actgacaagt cggataaggc
     8461 tcaaggaaat gcaattacat atgcgccgcg attaaccgtt ggttatcctg gtacattgcg
     8521 aacaggtagt tgttataact cttccctttg gtcgagtagc ccttcagctt gtgaatcatc
     8581 gctgtggcag tcacttcctg atccgcttta cgcagctgcg cacgcgattt acggaacgaa
     8641 gagtaagccg ggtgcgtatt caggttagtg acataggcgc tcaccgattc tttgacagaa
     8701 ctaaactgtg agtacccttt cactttacct ggcgcattgg tacaacgtcc tttcatgcat
     8761 ttcatgccga acaggttgtt gttgttgcgc gccagcttcg acgttcccca accgctttct
     8821 gctgcagcca tcgtcgccac catactggtg gggataatgt ctacgcgttc aagcaaggta
     8881 ttccacggga tttttcgcgt attaccggac cacttcacct tgtagcgttt ggcgatgtct
     8941 ttcagacgcg cacgctcagc aggtgaccat tggccctgat actgttttga aatgagccag
     9001 ttacgttccg cagtaatggc cgcattttgg ctggtaatgt aaggcattac ggtccggaga
     9061 aacgcctttt tccttggtgt tccggaaggg tattttcgca aatcaggaag tgaactactc
     9121 tttgcactat tgcgagaata ctcttgttta ctgcttacct gtttattact agctttagtt
     9181 aagtgggact tttgactcgc tgttgttgtg tgcgtcttcg ctaacacctc actcgaaaac
     9241 accagagtga gtaacataag aatcatcgcc ccatatcgtc gtatgggagt caaaatcatc
     9301 aggtctcctg gtcggattta atcattccaa caccttatat ttttcacaaa tttgagagtt
     9361 gaatctcaaa tcatatcaaa aatagctgtc aagagcaccc caaggaatag tccaaatctg
     9421 aaactatgtc acgtgttaac gattcagatt ggcgctaaat cgcagaaaat gtgggggtta
     9481 tcgcaaaatt cagccgtttt ttgcgcgaga tcgctcaccc ttgcttctca tcctgtggac
     9541 ttaccgctca gggatgagtt ttgtttggct tatcgctggc aaactgtctg aaatcgcagc
     9601 aataaggact catccgccat gaaactcgcc gcctgttttc tgacactcct tcctggcttc
     9661 gccgttgccg ccagctggac ttctccgggg tttcccgcct ttagcgaaca ggggacagga
     9721 acatttgtca gccacgcgca gttgcccaaa ggtacgcgtc cactaacgct aaattttgac
     9781 caacagtgct ggcagcctgc ggatgcgata aaactcaatc agatgctttc cctgcaacct
     9841 tgtagcaaca cgccgcctca atggcgattg ttcagggacg gcgaatatac gctgcaaata
     9901 gacacccgct ccggtacgcc aacattgatg atttccatcc agaacgccgc cgaaccggta
     9961 gcaagcctgg tccgtgaatg cccgaaatgg gatggattac cgctcacagt ggatgtcagc
    10021 gccactttcc cggaaggagc cgccgtacgg gattattaca gccagcaaat tgcgatagtg
    10081 aagaacggtc aaataatgtt acaacccgct gccaccagca acggtttact cctgctggaa
    10141 cgggcagaaa ctgacacatc cgcccctttc gactggcata acgccacggt ttactttgtg
    10201 ctgacagatc gtttcgaaaa cggcgatccc agtaatgacc agagttacgg acgtcataaa
    10261 gacggtatgg cggaaattgg cacttttcac ggcggcgatt tacgcggcct gaccaacaaa
    10321 ctggattacc tccagcagtt gggcgttaat gctttatgga taagcgcccc atttgagcaa
    10381 attcacggct gggtcggcgg cggtacaaaa ggcgatttcc cgcattatgc ctaccacggt
    10441 tattacacac aggactggac gaatcttgat gccaatatgg gcaacgaagc cgatctacgg
    10501 acgctggttg atagcgcaca tcagcgcggt attcgtattc tctttgatgt cgtgatgaac
    10561 cacaccggct atgccacgct ggcggatatg caggagtatc agtttggcgc gttatatctt
    10621 tctggtgacg aagtgaaaaa atcgctgggt gaacgctgga gcgactggaa acctgccgcc
    10681 gggcaaacct ggcatagctt taacgattac attaatttca gcgacaaaac aggctgggat
    10741 aaatggtggg gaaaaaactg gatcagaacg gatatcggcg attacgacaa tcctggattc
    10801 gacgatctca ctatgtcgct agcctttttg ccggatatca aaaccgaatc aactaccgct
    10861 tctggtctgc cggtgttcta taaaaacaaa atggataccc acgccaaagc cattgacggc
    10921 tatacgccgc gcgattactt aacccactgg ttaagtcagt gggtccgcga ctatgggatt
    10981 gatggttttc gggtcgatac cgccaaacat gttgagttgc ccgcctggca gcaactgaaa
    11041 accgaagcca gcgccgcgct tcgcgaatgg aaaaaagcta accccgacaa agcattagat
    11101 gacaaacctt tctggatgac cggtgaagcc tggggccacg gcgtgatgca aagtgactac
    11161 tatcgccacg gcttcgatgc gatgatcaat ttcgattatc aggagcaggc ggcgaaagca
    11221 gtcgactgtc tggcgcagat ggatacgacc tggcagcaaa tggcggagaa attgcagggt
    11281 ttcaacgtgt tgagctacct ctcgtcgcat gatacccgcc tgttccgtga agggggcgac
    11341 aaagcagcag agttattact attagcgcca ggcgcggtac aaatctttta tggtgatgaa
    11401 tcctcgcgtc cgttcggtcc tacaggttct gatccgctgc aaggtacacg ttcggatatg
    11461 aactggcagg atgttagcgg taaatctgcc gccagcgtcg cgcactggca gaaaatcagc
    11521 cagttccgcg cccgccatcc cgcaattggc gcgggcaaac aaacgacact tttgctgaag
    11581 cagggctacg gctttgttcg tgagcatggc gacgataaag tgctggtcgt ctgggcaggg
    11641 caacagtaac ttttccggct tcccgttcgt cagtacctcg ggaagccgcc aaccaggata
    11701 aaatgtcagc cctaatcagc gttgcaggat aaagcaccgc tcactcttca acagaccgat
    11761 ttgcacccca gcaaatgtag cgttattgtt accttccttg ctacagagtt cgacagatat
    11821 cccgctatga cattctccct ttttggtgac aaatttaccc gccactccgg cattacgctg
    11881 ttgatggaag atctgaacga cggtttacgc acgcctggcg cgattatgct cggcggcggt
    11941 aatccggcgc agatcccgga aatgcaggac tacttccaga cgctactgac cgacatgctg
    12001 gaaagtggca aagcgactga tgcactgtgt aactacgacg gtccacaggg gaaaacggag
    12061 ctactcacac tgcttgccgg aatgctgcgc gagaagttgg gttgggatat cgaaccacag
    12121 aatattgcac taacaaacgg cagccagagc gcgtttttct acttatttaa cctgtttgcc
    12181 ggacgccgtg ccgatggtcg ggtcaaaaaa gtgctgttcc cgcttgcacc ggaatacatt
    12241 ggctatgctg acgccggact ggaagaagat ctgtttgtct ctgcgcgtcc gaatattgaa
    12301 ctgctgccgg aaggccagtt taaataccac gtcgattttg agcatctgca tattggcgaa
    12361 gaaaccggga tgatttgcgt ctcccggccg acgaatccaa caggcaatgt gattactgac
    12421 gaagagttgc tgaagcttga cgcgctggcg aatcaacacg gcattccgct ggtgattgat
    12481 aacgcttatg gcgtcccgtt cccgggtatc atcttcagtg aagcgcgccc gctatggaat
    12541 ccgaatatcg tgctgtgcat gagtctttcc aagctgggtc tacctggctc ccgctgcggc
    12601 attatcatcg ccaatgaaaa aatcatcacc gccatcacca atatgaacgg cattatcagc
    12661 ctggcacctg gcggtattgg tccggcgatg atgtgtgaaa tgattaagcg taacgatctg
    12721 ctgcgcctgt ctgaaacagt catcaaaccg ttttactacc agcgtgttca ggaaactatc
    12781 gccatcattc gccgctattt accggaaaat cgctgcctga ttcataaacc ggaaggagcc
    12841 attttcctct ggctatggtt taaggatttg cccattacga ccgagcagct ctatcagcgc
    12901 ctgaaagcac gcggcgtgct gatggtgccg gggcacaact tcttcccagg gctggataaa
    12961 ccgtggccgc atacgcatca atgtatgcgc atgaactacg taccagagcc ggagaaaatt
    13021 gaggcggggg tgaagattct ggcggaagag atagaaagag cctgggctga aagtcactaa
    13081 aaattgcctg atgcgctacg cttatcaggc ctacatgatt tctgcaatat attgaatttg
    13141 gaagaatttg taggccggat aaggcgttta cgccgcatct ggcataaaca aagcgcactg
    13201 ttccggcgtt gagaaacgcc ggaaaacgtt tcaaacaggc tgctgccgta gccgatgccg
    13261 ctgcactttc tcgacatcca tgcactgcaa cgcctttgtc gggcaggctt caacacaggc
    13321 cggtcccgtc tcccgatgcc agcacagatc gcacttaatc gccctcgcct ttttgcgcga
    13381 agaaacgacc tccatcgcac caaacgggca agccagcata cagcttttac agccaatgca
    13441 acgtgtttgt tcaacgaaaa tatgcccatg ttcgcggctt atcgcgtcaa cagggcagac
    13501 attcgcgcac ggtgcatctt cacactgatg acaggctact gccgtggtcc agcagtggtc
    13561 tttaatgaca cgaatacggg aaataaactc gtctggtgac aacgcagcgc aatcctgatt
    13621 ctcatgatgc gacactgcgc aagccacttc acaggtacgg caaccgatac atttcgtcgc
    13681 atccgcaata ataaaccggt tcatgatcac tcctttgcac taaaacagca gagtgccaga
    13741 gagcgcgtcc ctactgcttt gatccaacga aggaaatgtt aaagttttgg cacttgtcca
    13801 aagcgttatg tgatcgcgcc caggtcatcc ctgacagtaa atcccagttc attagaaata
    13861 gcctgcgcgg tttcacgcag tggtttcagg agatttttct ctcccacctg tttcagacgt
    13921 gatgtcgaaa gcgaaatcga cacggcgtac ggcacccgcc catgaatatc aaacaccgga
    13981 acagcaatac aggagacgcc gagttcgttt tcttctctgt ccatcgccgc tccgctttca
    14041 cgaatgtgcg ccagttcgtc gaacatcgcg ggcagctcgg taatggtatt gcgggttaac
    14101 ggctggatct catgctgatg gctttcccag tatgacttca cgtagtccgg gtgaccaaac
    14161 gccatgtaga tcttgcccat tgcggaacag tagagcggca tatgctggcc aatataggca
    14221 cgggttcgca gcatcccggt tgtgggttcc agcttataaa tcaaaatagc gtgatcgtct
    14281 tcgcggctgg agaagttaat ggtttcacca gtggcgatgt tcagtgcctc aagatgcgga
    14341 gcggcgatat gaatgatatt cagcgaagac agcgccttct gcccgacggc aataaatttg
    14401 gtggtcaggc gataactccc tgcggcaggc gcggtggtca catagccgca ggactgtaat
    14461 ccctgcaata agcgatggac ggtactctta tttaaaccag ccagctccga aagatgcgcc
    14521 aacggacaac cgtttggata gttgctcaaa atctcaatca gcatcaaccc gcgaaacaga
    14581 ctctggcttc cggctggacg ctctttttcc tgcgccatct cgttctcttt ttttcccatc
    14641 acttctttcc ccattttgtc gcgtcctgat ggtagcgcaa agtgtgccgt agttcacgat
    14701 ctcgacagat aatttataac caattgattt ttatgtcttt tgaaattcat caatcagatt
    14761 gctttgttaa aaagtgatcg atatatttga aatcaagttt cgcatattga aattttaagc
    14821 caaaaaagcg atcaaaaaaa caaggaagcc tgggatgaaa gtgacatttg agcagttaaa
    14881 agcagccttt aatcgggtct taatttcacg cggcgttgac agcgaaacgg ctgacgcctg
    14941 tgcagagatg ttcgcccgca ccaccgaatc cggcgtttat tctcacggcg ttaatcgttt
    15001 ccctcgtttc attcaacaac tggaaaacgg cgatatcatt cctgatgccc aacccaaacg
    15061 tataaccagc ctcggcgcaa ttgaacagtg ggacgcccag cgttcgatcg gtaacctgac
    15121 agcgaaaaag atgatggatc gcgccattga actggctgcc gatcacggta ttggtctggt
    15181 ggcactacgt aatgccaacc actggatgcg cggcggcagc tacggctggc aggcggcgga
    15241 aaaaggctat attggcattt gctggaccaa ctccatcgcc gtaatgccgc cgtggggcgc
    15301 aaaagagtgt cgcatcggca ctaacccgct gatcgtcgcc attccttcca cgccgatcac
    15361 catggtcgat atgtcgatgt cgatgttctc ttacggcatg ttagaagtta accgtctggc
    15421 aggtcgtcag ctcccggtcg atggtggctt tgatgatgag ggcaatttga ccaaagaacc
    15481 tggcgttatc gagaagaatc gccgcatttt gccgatgggc tactggaaag gttctggcat
    15541 gtcgattgtg ctggatatga tcgctactct cctttccgac ggcgcatccg ttgccgaagt
    15601 cacccaggac aacagcgacg aatacggcat ttcacaaatt tttattgcca ttgaagtgga
    15661 caagcttatc gacggtccca cccgcgatgc caagctgcaa cgcatcatgg attacgttac
    15721 tagtgccgag cgtgctgacg aaaatcaggc cattcgctta cccggccatg aatttactac
    15781 cctgctggcc gaaaaccgcc gtaacggcat cactgttgat gacagcgtgt gggccaaaat
    15841 ccaggcgtta tgaggagata agtcatgatt tttggacata tcgcgcagcc caatccgtgc
    15901 cgtttgcccg ccgccattga aaaggcgctc gattttctgc gcgctaccga tttcaacgcc
    15961 ctggagccgg gcgttgtcga aatcgacggc aaaaatattt atacgcaaat tatcgattta
    16021 accacacgcg aagcggtggt aaaccgtccg gaagtgcatc gtcggtatat cgatattcag
    16081 tttctggcgt ggggcgaaga gaaaatcggc attgctattg atacgggaaa taataaagtc
    16141 agcgaatcac tattagagca gcgcaatatt attttttatc acgacagtga acatgaatca
    16201 tttatagaaa tgataccggg cagctacgca attttctttc cgcaggatgt tcaccgacca
    16261 ggttgtatta tgcaaacagc ctctgagata cgaaaaattg tggttaaagt cgcattaacg
    16321 gcgctgaatt aatcgaataa tcgtctacgc cagaacgcct gggtaatgtt attgctctaa
    16381 ctatattaat aattcaggtt gctgcacatg cgacttgaat tatgacagac atagcctcaa
    16441 ggaatagcta tgaaaaaaat actcgaagca atactggcga ttaatctcgc cgtactttcc
    16501 tgtattgtat ttataaacat tattttaaga tatggttttc agacaagcat tttatctgtt
    16561 gatgaattgt cacgttattt atttgtctgg ttaacgttta ttggcgcgat tgtagctttt
    16621 atggataacg cccacgttca ggtcaccttt ctggtggaga aactctcccc cgcatggcag
    16681 cgacgagtcg ctctggttac ccattcctta atcttattta tttgtggcgc actggcctgg
    16741 ggcgcaacgc taaaaacaat tcaggactgg agcgattatt caccgatcct cggtttaccc
    16801 atcggcctga tgtatgccgc ttgtctgccc accagcctcg ttatcgcatt ctttgaactg
    16861 cgtcatttat atcaactcat cacgcgtagc aattctctaa cgtcgccacc gcaaggagct
    16921 taatcatggc tgtgctgatt tttctgggct gtctgttggg tggtattgct atcggtttgc
    16981 ctattgcctg ggcactgttg ttgtgcgggg cggcgttaat gttctggctg gacatgtttg
    17041 atgtccagat catggcacaa acgctggtga acggagccga tagcttctcc ctgctggcga
    17101 ttccgttctt tgtgctggcg ggtgaaatca tgaatgcggg cggcttgtca aaacgcattg
    17161 ttgacctgcc gatgaaactg gtggggcata aaccaggcgg gctgggctac gtcggcgtgc
    17221 tggcagctat gattatggcg agcctttctg gttctgccgt tgcggatacc gccgccgttg
    17281 ccgctctact ggtgccgatg atgcgcagcg ccaactatcc ggtcaaccgg gcggcggggc
    17341 tgattgcctc tggcggcatt atcgcgccaa ttattccccc ttccattccg tttattatct
    17401 tcggcgtttc cagcagatta tccatcagta agctgtttat ggcgggcatt gcccctggca
    17461 tgatgatggg cgcaacgctg atgcttacct ggtggtggca ggccagtcgc cttaatttac
    17521 cccgccagca aaaagcaacg atgcaggaaa tctggcactc ttttgtctcc ggtatctggg
    17581 cgctgtttct tccagtcatc attattggcg ggtttcgctc cggtctgttt acccctaccg
    17641 aagccggggc cgttgctgct ttctatgcgc tgtttgtcgc cacagttatt taccgtgaaa
    17701 tgaccttcgc cacactttgg catgtactca ttggcgcggc gaaaaccacc tcagtggtta
    17761 tgtttctggt ggcctcggca caagtttccg cctggctgat taccattgct gaactgccga
    17821 tgatggtttc tgatttactg caaccgttgg tcgattcacc gcgtctgctg tttatcgtca
    17881 ttatggtggc tatcctgatt gtcggcatgg tcatggattt aacgccgacg gtattaattc
    17941 ttaccccggt attaatgcct ttagttaaag aggcaggaat cgatccgatt tatttcggtg
    18001 tcatgtttat cattaactgc tcaatcggct taattacacc gcctatcggt aatgtactta
    18061 acgttatttc aggggtggca aaactcaaat tcgatgatgc agtcagaggc gttttccctt
    18121 acgtcctggt tttatattca ttattagtcg tatttgtttt tattcccgat ctcatcatcc
    18181 tccctttgaa atggattaat taaaaggaaa atattatgaa attacgctct gtaacctacg
    18241 cattattcat tgctggcctg gctgcattca gcacatcttc tctggcggca caatctttac
    18301 gtttcggtta tgaaacatca caaaccgact cgcaacatat tgcggcgaaa aaattcaatg
    18361 atttattgca ggagagaacc aaaggcgagc tgaaattaaa actgttcccg gacagcactc
    18421 tcggtaacgc gcaggcgatg atcagcggcg tacgtggcgg caccatcgat atggaaatgt
    18481 ccggctcgaa taactttgcc gggttatcac cagtgatgaa cttgcttgat gtccctttcc
    18541 tgttccgcga taccgctcac gcgcataaaa cgctcgacgg caaagtcggt gatgatctga
    18601 aagcctcact tgaaggtaaa ggactgaaag tactggccta ctgggaaaac ggctggcgcg
    18661 atgtcaccaa ctcgcgcgca ccggttaaaa cccccgccga cctgaaaggg ctgaaaatcc
    18721 gcaccaacaa tagcccgatg aatatcgccg cattcaaagt ctttggcgct aacccgatcc
    18781 cgatgccgtt tgccgaagtc tataccgggc tggaaacccg cactatcgac gctcaggaac
    18841 acccgatcaa cgtcgtctgg tcagcaaaat ttttcgaagt gcagaagttc ctttctctga
    18901 cgcaccacgc ctattccccg cttctggtgg tgatcaacaa agcgaagttt gatggcttaa
    18961 gtccggagtt ccagcaggcg ctagtttcat ctgcacaaga agcgggtaac tatcagcgca
    19021 aactggttgc tgaagatcag caaaaaatca tcgacggcat gaaagaagcg ggcgtggaag
    19081 tcatcaccga tctcgaccgc aaagccttta gcgacgcact ggggaatcag gttcgcgaca
    19141 tgtttgttaa agatgtgccg cagggagctg atctgctgaa agccgtggat gaggtgcaat
    19201 aaaccatgac gcaatactgg ctggggttag attgtggcgg tagctggctg aaagccgggc
    19261 tgtatgaccg cgaaggccgg gaggcaggcg tgcagcgcct gccgctgtgc gcattaagcc
    19321 cgcagccagg ctgggcagag cgcgatatgg cagaactgtg gcaatactgc atggctgtca
    19381 ttcgcgccct gcttactcat tctggtgtta gcggggaaca aattgtcggt atcggcatct
    19441 ccgcacaggg aaagggcttg tttttgctgg ataaaaacga caaaccgctc gggaatgcta
    19501 ttttgtcctc ggaccgccgg gcgatggaaa tcgttcgtcg ctggcaggaa gatggcatcc
    19561 cggaaaaact ctacccgctg acccgacaaa ccttgtggac cgggcatccg gtgtcgctgt
    19621 tacgctggct gaaagagcac gaaccagaac gctacgcgca aattggctgc gtgatgatga
    19681 cgcacgacta cctgcgctgg tgtttaactg gcgtcaaagg ctgtgaagag agcaatattt
    19741 ccgagtccaa cctctacaac atgagtcttg gggaatatga cccgtgcctc accgactggc
    19801 tggggatcgc tgaaatcaat cacgccctgc cgcctgttgt cggatctgcc gaaatctgcg
    19861 gggagatcac cgctcagaca gccgccctga ccggtctgaa agcgggtacg cccgttgttg
    19921 gcggcctgtt tgatgtggtt tccaccgcac tctgcgccgg gatcgaagac gaatttaccc
    19981 tcaatgcggt gatggggacc tgggcggtga ccagcggcat aacccgcggt ttacgtgacg
    20041 gtgaagcgca tccgtatgtc tatggtcgct acgttaacga tggtgaattt atcgttcacg
    20101 aagccagccc tacctcttcc ggcaacctcg aatggtttac cgcacagtgg ggagaaatct
    20161 cgtttgatga gatcaatcag gccgttgcca gcttgccgaa ggctgggggc gatctctttt
    20221 tcctgccgtt cctgtacggc agcaacgccg gactcgagat gaccagtggt ttctacggga
    20281 tgcaggccat tcacacccgc gcgcacctgt tgcaggccat ctatgaaggg gtggtgttca
    20341 gccatatgac ccacctcaac cgaatgcgcg aacgttttac tgatgttcac accctacgcg
    20401 tcactggcgg cccggcgcac tccgatgtct ggatgcaaat gctggcggac gtcagcggtc
    20461 tgcgtatcga gctgccgcag gtggaagaaa ccggctgctt tggtgcggcc cttgccgccc
    20521 gcgtcggcac cggggtttat cacaacttca gcgaagccca acgtgacttg cgacacccgg
    20581 tgcgcaccct gctgccagat atgaccgccc atcagcttta ccaaaaaaaa tatcaacgtt
    20641 atcagcatct cattgccgca cttcagggct ttcacgcccg cattaaggag cacacattat
    20701 gagccgacca cttctgcaac tggccctcga ccactcatca cttgaagccg cgcagcgcga
    20761 cgtgacgctg ttaaaagaca gcgtcgatat cgtcgaagcg ggcaccattc tctgtttaaa
    20821 cgaagggctt ggcgcggtga aagccttgcg cgaacagtgc ccggacaaaa tcatcgttgc
    20881 tgactggaag gtcgccgacg ctggtgaaac gctcgcgcaa caggcgtttg gcgcaggcgc
    20941 taactggatg accatcatct gcgccgcgcc gctcgcgacg gtagaaaaag gccacgcaat
    21001 ggcacaacgc tgcgggggtg aaattcagat agagctgttc ggtaactgga cgctggacga
    21061 cgcccgcgac tggcatcgta ttggcgtgcg gcaggccatt tatcatcgcg gtcgtgatgc
    21121 acaggccagc gggcaacagt ggggcgaagc cgatctggca cgcatgaagg cgctttcaga
    21181 tatcggcctt gagctttcca ttactggcgg gattacccct gctgacctgc cgctgtttaa
    21241 agatatccgc gtgaaagcgt ttattgccgg gcgggcactg gcaggcgcgg caaatccggc
    21301 gcaagtggct ggcgatttcc atgcgcaaat cgacgctatc tggggaggtg cgcgtgcgta
    21361 atcatccgtt agggatttat gaaaaagcgc tggcgaaaga tctctcctgg ccggagcggc
    21421 tggtgctggc aaaaagctgc ggttttgatt ttgtcgaaat gtcggtggat gaaaccgacg
    21481 aacggctctc acgtcttgac tggagcgccg cacaaaggac ttcgctggtt gccgcgatga
    21541 tcgaaacagg tgttgggatc ccgtcgatgt gcctgtccgc acatcgtcgc tttccctttg
    21601 gtagccgtga cgaggcagtg cgcgaacggg cgcgggaaat catgagtaaa gcgattcgcc
    21661 tggcgcgcga tctcggcatt cgcaccatcc agctggcagg ttatgacgtc tattacgaag
    21721 accacgacga aggcacccgg caacgttttg ctgaagggct ggcgtgggca gtcgaacagg
    21781 cggcggcatc acaagtaatg ctggcggtgg agattatgga taccgcgttt atgaactcca
    21841 tcagcaaatg gaaaaaatgg gacgagatgc tcgcctcgcc gtggttcacc gtctacccgg
    21901 acgtcggcaa cctcagcgcc tggggcaatg atgttcccgc cgaactgaaa ctgggcattg
    21961 accgtatcgc cgcgatccac ctgaaagaca cccagccagt taccgagcaa agtcccggac
    22021 agttccgcga cgtgccgttt ggcgaaggct gcgtcgattt cgttggcatc ttcaaaacgc
    22081 tgcataaact gaactatcgc ggttctttcc tgattgagat gtggaccgaa aaagccaaag
    22141 agccggtgct ggagattatt caggcgcggc gttggattga agcgcgtatg caggaggctg
    22201 gatttatatg ttagagcaac tgaaagccga cgtgctggcg gcaaatctgg cgcttcccgc
    22261 tcaccatctg gtgacgttca cctggggcaa tgtcagcgcg gtagacgaca cgcggcaatg
    22321 gatggtaatc aaaccttccg gcgtcgaata cgacgtgatg accgccgacg atatggtggt
    22381 ggttgagata gccagcggta aggcggtgga aggcagcaaa aagccctctt ccgatacgcc
    22441 aacgcatctg gcgctctacc gtcgctatgc agagatcggt ggcattgtgc atacccactc
    22501 gcgccacgcg accatctggt cacaggccgg gctggatctc cccgcctggg gcaccaccca
    22561 cgccgattat ttttacggtg ccatcccctg cacgcgccag atgaccactg aggagatcaa
    22621 cggcgagtat gaataccaga ctggcgaagt gatcattaaa accttcgaag aacgtggttt
    22681 gaacccggca caaatcccgg cggtactggt acattctcac ggcccgttcg cctggggaaa
    22741 aaacgccgcc gatgcggtgc ataacgccgt ggtgctggaa gagtgcgcct atatgggcct
    22801 gttctcgcgc cagcttgcgc cgcagctccc tgccatgcaa aacgaactgc tggataaaca
    22861 ctacctgcgt aagcatggag acaatgccta ttacgggcag taatccctca cgccggggct
    22921 tcatcgcccc ggcactacga attgatatgt tccttgctgt aacgccgttt ccacgctgct
    22981 ggcgttaaac cggtgtgttt gcgaaaaatc tgccggaaaa agccaacgtc attaaaccgt
    23041 attgcatgga gcaggccgac aacgtcgagt cactgcataa cctgttgctg cccgccgatg
    23101 cgccatttac gacatttgaa ggcaagggat tgttcagcca taagatcctg attcagacgc
    23161 caggttcccg gtatgaacag agcaatccag agcaacaacc tttgtggcat tacgacggag
    23221 caccagccgc accaacatcc accggtgaat taaaaacgcc agctcacgcc ggtgacaaag
    23281 gtaaaactct cattacgatc aatcatcggg ctgtcggtaa tctcttccgg cagctcgctg
    23341 tatcctgcac tcgccatcaa tacgacgtgc tctcctatcg ggtattttgc cgtcaggctg
    23401 acatagggca cccaggcatc ctgcgcggaa taacttgcca gaccgctacg acgggactca
    23461 ctctctgaaa tgccatagta atagtcactg aaattctcgt cataatagag cacgcccagc
    23521 gcaggtgtca gcgacaggcg acctatctgc attttgtgga aaaccgatag ctcccccacc
    23581 cagccgttgc tgttatccag aacgtccgca gccgcagagg ctttcacagt tccccaacgc
    23641 tcgtggtgat accaggcaac ccccgccata gccgtactat cacgcttatc aagctgttgc
    23701 atggcataat cgtcattatc ggcagggtca aattccagcg gcatccagga tgcggtcagg
    23761 ctaagttcat ttttttcact ttgcgacaga ataaaaccta acgtggtctg acgaacataa
    23821 aaagaatcac cttcataact aatcagggga attgcctttg tattttcatt ataaccgcga
    23881 taaggcgatt cattataagc cgcaccggca ccaatggata attcagaagc agttgcgctt
    23941 gccataaaag gcaacgcaaa taacgccaca atattgcggt taattaacat gttcggtatt
    24001 ccattttaaa ataagataaa aaagagtcgg catagtaatg cttacaattt ctccggtgca
    24061 agattcatat ttatatagta atatataaaa ttatatataa ttgggctgtt gcgatgacaa
    24121 aattacaact taagtaccgg gagttaaaaa ttatctcggt aatcgctgcc agtgaaaata
    24181 tcagccatgc cgcgactgta cttggcatcg cacaggccaa cgtcagcaaa tatcttgctg
    24241 attttgaatc aaaagtgggt ttaaaagtct ttgaccgaac cacccggcag ctgatgctca
    24301 caccttttgg taccgcgctg ttaccgtaca tcaacgacat gctggacaga aacgagcagc
    24361 ttaataattt tattgcagat tataagcatg agaaacgtgg tcgggtcacc atctacgccc
    24421 caaccggcat aattacctat ttatccaaac atgtaatcga taaaattaaa gatatcggtg
    24481 atatcacctt atcgctaaaa acctgcaatc ttgagcgtaa tgccttttat gaaggcgtcg
    24541 aatttcctga tgattgtgat gttttaatca gctacgctcc accaaaagat gaatcgctgg
    24601 ttgccagttt tattacccaa tatgccgtaa ccgcttatgc cagccagcgc tatcttgaga
    24661 aacatcccat tagccgtcct gacgaactcg aacatcactc ctgtattttg atcgactcga
    24721 tgatgatcga cgacgcgaat atctggcgct tcaacgtcgc cgggagtaaa gaggtgcggg
    24781 attatcgcgt gaagggaaat tacgtttgcg acaacacgca atctgcgctg gagctggcac
    24841 gaaatcacct ggggattgtg tttgcgccag acaaaagtgt gcagagcgac ctgcaagacg
    24901 gcacgctggt gccctgcttt cagcaaccct atgaatggtg gctggatctg gtggctatct
    24961 tccgtaaacg ggaataccag ccctggcggg tccagtatgt gctggatgaa atgctgcgtg
    25021 aaattcgcca ccagcttgct cagtcgcagc aactgcggcc tgaacaagcg gcggaaagcg
    25081 aagattaatg atcgagataa aggtaatgca cccagctggt catgcgtaat agcactttgc
    25141 gcatcaccga gacatggctg aaatgatcag agtaaaccgc cacctgggcg taaataccgt
    25201 ctggtaaagc gctcaaatca gtgtgctcat ccagttcaat ggtcgcgata acgccatctg
    25261 aacccggcgc tgtgtttaac gtctgtaagg tgccggtcga ctgataagct ccgccgggaa
    25321 cggttggact aatggctgcc agcttaccgc tgaatacctt acctggcaga gcattaaaca
    25381 ccacttccgc atcgtcgcca ggagccagtc gcagcaagga gttctgacgg aactgcgcca
    25441 cgatttgtcg tttctgatcg ggtataaaca ccatcaccgg acgtagcggc agcgacgcgg
    25501 cataggtacc cggacgaatc agtacctggg tcacataacc atcgctcggc gcacgcacta
    25561 tcgtctgctc aaggttatat tttgcttccg cgagctgtgc tttcaggctg gcgatttgag
    25621 aatgttcacc caacaccagg ctatccagct ggctctggat ctgtttttgt tccgccgccg
    25681 atgacttcac ggaggcttcc tgcgccagat aattttgccg cgccacatcg atatcgcgtt
    25741 ctgaaaacgg gtttactttc gcctggctgc cacgtgcgta acgctgatac tctttagcga
    25801 atttatcccg cgtggccttt gcctgctgag tattcgccgc catctcatct aactctgcgc
    25861 ccaacgcccg ctgtttatgt tctgcggtaa cgatatccgc catcagccga tccacccgcg
    25921 cctgataacg cgtcgggtcc agtcgaaata gcacctcacc ttttttaatc agcgtatttt
    25981 tcttatccgt cacttcaatc accacaccag tcacctgtgg gacaacagga atagaaataa
    26041 ccgctttttg cgctttaaag gtatacggat ggttatagtt cattaacaga attagaccgc
    26101 tgacaataaa tattccaccc agggccgctg tgggaatggt ccatttattt acgggaattt
    26161 tgaagatctt aaacattgcc catgcaaaag ccacataggt caaaataatc agtaaatcca
    26221 taagtattac tcggcagaag aggatttgat gtcggcgagc tgtttctcca gcccggcaat
    26281 gcgctgttgc agttgcataa cggatgaatc atggctttgc attccccatc cccgctccgg
    26341 gcggtaaagc gtggcccaaa tccacaaaaa cggccagata acatgtaacg taaaaagact
    26401 cacccaacca gcaacatgaa tggcgtcggc atgaggatga ttacgttttt tggcaatcag
    26461 gtagggaata tcatgtaaaa taatgatccc atagaagatc accagaaata caaaaataag
    26521 cactcccagt gcaaaatagt ccaggaacat atttccctca aagaatataa aaaagaacaa
    26581 ttaacgcata ttatgaaatg ccatgatgca gtgcaatttc cttatttata taacgacata
    26641 ttgtttttta tatactttct taaatgtgct gtctggtttt tcaacaggac gaggtttatc
    26701 atattgaaat agtggaacta ttggccaaac taatgaataa ctccagtaaa acatccacag
    26761 tacagattaa gcgtattaaa ccttcaatta tctaccgttt attgctgatt ggcctcggat
    26821 caccaatggt gatttacggc ctggttcgcc cgctcaccat cgaaacgcga gattaaactc
    26881 ctgacaaaac acgccccaga aacgcacttc tgttggcgta gtctgggtta ttgcgcacgt
    26941 aggtttaaaa cgtaaattgt aacaacgtgc gctttgttta tgccggatgc ggcgtgtacg
    27001 ccttatccgg cctacggtca ggttcccgta ggcatgataa gacgcgtaag cgtcgcatca
    27061 ggcaatgaat acccaatgcg accagcttct tatatcagaa cagccccaac ggtttatccg
    27121 agtagctcac cagcaggcac ttggtttgct ggtaatgctc cagcatcatc ttgtgggttt
    27181 cgcgaccgat acctgattgt ttgtagccac caaacgccgc atgtgccggg taagcgtgat
    27241 aacagttggt ccacacgcgc ccagcctgta tgccgcgccc catcttatag gccagattac
    27301 cgttgcggct ccagacgccc gcgcccaggc catattgcgt atcgttcgcc agctccagcg
    27361 cttcttccat cgttttgaag gtggtcaccg ccagcaccgg gccaaaaatc tcctcctgga
    27421 acacccgcat attgttctga ccaaacagaa tcgtcggttc gaggtagtag ccgtctttca
    27481 gttcaccttc cagcagcttg cgccgcccgc ctgtgagcac gtcagcgccc tcttttttac
    27541 cgatatcaat gtagttgagg atggtttcca gttgcccgtg agaaacctgc gcgcccattt
    27601 gcgtcacgct gtcgagcggg ttaccgctac gaatgctttc gacacggcgg atggcgcgtt
    27661 ccataaagcg ttcgtagata gattcctgca ctaaagcacg actcggacag gtgcaaactt
    27721 cgccctggtt aaaggcaaac agtgcaaagc cttccagcgc tttatcgaaa aaggcatctt
    27781 cttcatccat cacatcagca aagaagatat ttggcgattt gccgcccagc tccagcgtca
    27841 ccggaataat gttttgcgtg gcgtattgca taatttgttg gcccacttcc gttgagccgg
    27901 taaacgccac tttggcgatg cgtttcgagg tagccagata ttcgccaatt accccacctg
    27961 cgccattgac cacgttcacc acgcccggcg gcagtaaatc accgacaatt tccattagca
    28021 gcagtacaga aagcggggta agacgtgcgg gtttcagcac cacacagttg cccgccgcca
    28081 gcgcgggagc cattttccag ctcgccatca gcagcgggaa gttccacggg ataatctgcc
    28141 ccaccacgcc taacggttca tggaaatgat aggccacggt ttcgctatca acttcactga
    28201 tcccaccttc ctgcgcccga atacacgagg cgaaatagcg aaaatggtca atcgccagcg
    28261 gcacgtcggc agcactggtt tcgcgaatgg gtttgccgtt atcccaggtt tcagccgtcg
    28321 ctaacagctc aaggttttgt tccattcgat cggcaatctt aaacagaatc gccgcgcgat
    28381 cctgcaccga ggtgtgcgcc catttatctt tcactttgtg cgcagcatcc agcgccagat
    28441 cgatgtctcg tttgcccgaa gacgccactt cgcacagcag ctgcccggtc accggcgtca
    28501 gattctggta atactcgccg tcggcagggg ctacccattc gccgccaata aagttgtcat
    28561 agcgggcttt taacttgagg gggaaaccat actcgccggg cttaatctgt actgaagggg
    28621 gattattggt catgatcgtc tccttgcggt gtgaggtata acaagggtag acgtgactgg
    28681 cgaaatcttc gccagtcggt aacagcttta cgacagctat cacgaattta cgggcaaggg
    28741 ttacagagat agttgaaaaa gcggctgaca atttgccagc cgttgtggaa atgatgatta
    28801 catcgctgcg cgataaatcg ccacaatttc ttcgtgagtt gcctggatcg ggttagtaaa
    28861 accacaggca tctttcaggg cattagttgc cagaaccgcg aaatcttctt ctttcacgtt
    28921 caggtcgcgt aggcctgccg ggatatccac tttcttcgcc agttcacgga tggcgttaat
    28981 gcaggcttca gcaccttccg catcgttttt acctgtcacg ttcacgccca ttgcagcggc
    29041 acagtcacgc agacgtgcgg cggcgacttt gctgttgaat acctgaacat gcggcagcaa
    29101 aacggcgtta catacaccgt gtggcaggtt gtagaaaccg cccagctggt gcgccatcgc
    29161 atgaacataa cccagagaag cattattgaa cgccataccg gcgaggaact gggcataagc
    29221 cattgcttca cgcgctttcg cattactgcc atcttcaacg gctaacggca ggttttcggc
    29281 aatcatggtc acggctttca gtgcacaagc gtcagtgatc ggcgtggcgg caatagaaac
    29341 atacgcttcg atagcgtgcg ttaaggcgtc cataccagtg gcggcggtca gtgacttcgg
    29401 cataccgatc atcagcgagg agtcattgac agaaagcagc ggagtcacgt gcttatcaac
    29461 aatcgccatt ttgatgtgac gcgcttcgtc ggtgatgatg cagaaacgag tcatttctga
    29521 tgctgtaccc gcagtggtat tgatggcgat catcggcagc tgcggttttg cagagcggtc
    29581 aacgccttca taatcacgga tatcaccacc attggctgcc accagcgcaa taccttttgc
    29641 acagtcatgc ggagaaccac cgcctaagga aatcacgcta tcgcaattat tttctttaag
    29701 taatttcaaa cctgcggcga cgttttccgt gattgggtta ggttgggtgc catcataaat
    29761 aacgctaaaa atattgcgtt cttccagtgc tttttgcaca tcacccgcca tacctaattt
    29821 cgttaacata ttgtcagtga caattaaggt acgggtaaat ccataatctg ccatcatatt
    29881 cattgcatca gtcaatgaat cagcgccgat gacattcaca gaaggaataa agaaagttga
    29941 agatgccata acacactcct gaaagtgtaa aaaagggcgg gcagcttact gaggattttc
    30001 attcgaaaat atgatcagta ttattgatt
//
LOCUS       DAPHKZ010000050        29661 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.050, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000050 DAPHKZ010000000
VERSION     DAPHKZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29661
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.050"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..847)
                     /locus_tag="RH288_002323"
     CDS             complement(<1..847)
                     /locus_tag="RH288_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MASE4 domain-containing protein"
                     /protein_id="HDV4031370.1"
                     /translation="MEKDYLRISSTVLVSLLFGLALVLVNSWFNQPGVEEVVPRSTYL
                     MVMIALFFIDTVAFIFMQLYFIYDRRQFSNCVLSLAFLSCLIYFVITVIIIQQIIEER
                     LTSSVVQNDIAIYYLFRQMSLCILIFLALVNKVSENTKQRNLFSKKMTLCISLFFVFG
                     GPIVAHILSSHYESYNLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNGLRY
                     DIWNGVTVIAFCAVLYNISLLFMSRYSVSTWYISRTIEVVSKLTVMVIFMCHIFSALR
                     VTKNIA"
     gene            1434..3857
                     /gene="pgaA"
                     /locus_tag="RH288_002324"
     CDS             1434..3857
                     /gene="pgaA"
                     /locus_tag="RH288_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine export
                     porin PgaA"
                     /protein_id="HDV4031371.1"
                     /translation="MYSSSRKRCPKTKWALKLLTAAFLAASPAAKSAVNNAYDALIIE
                     ARKGNTQPALSWFALKSALSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYA
                     AVAVAYRNLQQWQNSLTLWQKALSLEPQNKDYQRGQILTLADAGHYDTALVKLKQLNS
                     GAPDKANLLAEAYIYKLAGRHQDELRAMTESLPENASTQQYPTEYVQALRNNQLAAAI
                     DDANLTPDIRADIHAELVRLSFMPTRSESERYAIADRALAQYAALEILWHDNPDRTAQ
                     YQRIQVDHLGALLTRDRYKDVISHYQRLKKTGQIIPPWGQYWVASAYLKDHQPKKAQS
                     IMTELFYHKETIAPDLSDEELADLFYSHLESENYPGALTVTQHTINTSPPFLRLMGTP
                     TSIPNDTWLQGHSFLSTVAKYSNDLPQAEMTARELAYNAPGNQGLRIDYASVLQARGW
                     PRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDVVEREPQDPGVVRL
                     KRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLKDNWRGFAGFGYADG
                     QFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWRIGS
                     QLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRKYGVSWAFTDFSDSNQRHEVSLE
                     GQERIWSSPYLIVDFLPSLYYEQNTEHDTPYYNPIKTFDIVPAFEASHLLWRSYENSW
                     EQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLY
                     VEFDMTFRF"
     gene            3866..5884
                     /gene="pgaB"
                     /locus_tag="RH288_002325"
     CDS             3866..5884
                     /gene="pgaB"
                     /locus_tag="RH288_002325"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     N-deacetylase PgaB"
                     /protein_id="HDV4031372.1"
                     /translation="MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPW
                     PHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGK
                     PLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVD
                     REYFATWQQVREVARSRLVELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYET
                     AAEYRERIRLDAVKMTEYLRTKVEVNPHVFVWPYGEANGIAIEELKKLGYDMFFTLES
                     GLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKSPQRIMHIDLDYVYDENLQQMDR
                     NIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTR
                     SGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYHRLSPFDDRVRAQVGMLY
                     EDLAGHAAFDGILFHDDALLSDYEDASAPAITAYQQAGFSGSLSEIRQNPEQFKQWAR
                     FKSRALTDFTLELSARVKAIRGPHIKTARNIFALPVIQPESEAWFAQNYADFLKSYDW
                     TAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQAKDKSILELQAQNWQKNGQHQAISS
                     QQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDLIRPEFSTAWYPKND"
     gene            5877..7202
                     /gene="pgaC"
                     /locus_tag="RH288_002326"
     CDS             5877..7202
                     /gene="pgaC"
                     /locus_tag="RH288_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HDV4031373.1"
                     /translation="MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIM
                     WIVGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRY
                     ENIEVIAVNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLV
                     CIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIK
                     RTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRA
                     LCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAF
                     TCLVGFIIYAVQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLMIENRYEHNLT
                     SSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG"
     gene            7204..7617
                     /gene="pgaD"
                     /locus_tag="RH288_002327"
     CDS             7204..7617
                     /gene="pgaD"
                     /locus_tag="RH288_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     biosynthesis protein PgaD"
                     /protein_id="HDV4031374.1"
                     /translation="MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAMDLLTGY
                     YWQSEARSRLQFYFLLAVANAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIP
                     DELYQQLQKSHRMSVHFTSQGQIKMVVSEKALVRA"
     gene            complement(7667..8455)
                     /gene="phoH"
                     /locus_tag="RH288_002328"
     CDS             complement(7667..8455)
                     /gene="phoH"
                     /locus_tag="RH288_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HDV4031375.1"
                     /translation="MGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMGGVEA
                     IGMARDSRDTSPILARNEAQLHYLKAIESKQLIFATGEAGCGKTWISAAKAAEALIHK
                     DVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIG
                     KVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLP
                     RGVCSGLSDALERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS"
     gene            complement(9076..10347)
                     /gene="efeB"
                     /locus_tag="RH288_002329"
     CDS             complement(9076..10347)
                     /gene="efeB"
                     /locus_tag="RH288_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
                     /protein_id="HDV4031376.1"
                     /translation="MQYKDENGVNEPSRRRLLKVIGALALAGSCPVAHAQKTQSAPGT
                     LSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLT
                     QGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
                     TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHA
                     ARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQ
                     FRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLAN
                     PRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALE
                     EYVKPIGGGYFFALPGVKDANDYFGSALLRV"
     gene            complement(10353..11480)
                     /gene="efeO"
                     /locus_tag="RH288_002330"
     CDS             complement(10353..11480)
                     /gene="efeO"
                     /locus_tag="RH288_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HDV4031377.1"
                     /translation="MTINFRRNALQLSVAALFSSAFMANAADVPQVKVTVTDKQCEPM
                     TITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMT
                     CGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
                     IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHR
                     LEKALFGDNTTKGMDQYAEQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKI
                     SGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKY
                     RTKDGFETYDKLTDADRNALKGPITALAEDLAQLRGVLGLD"
     gene            complement(11538..12368)
                     /locus_tag="RH288_002331"
     CDS             complement(11538..12368)
                     /locus_tag="RH288_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family protein"
                     /protein_id="HDV4031378.1"
                     /translation="MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLL
                     AAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLE
                     QAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLAT
                     AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFD
                     MSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
                     "
     gene            complement(12911..14419)
                     /gene="putP"
                     /locus_tag="RH288_002332"
     CDS             complement(12911..14419)
                     /gene="putP"
                     /locus_tag="RH288_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HDV4031379.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     YNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNDHPALAGAVNQNAERVFIELAQILFNPWIAGILLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAAN
                     PENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWL
                     GLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQES"
     gene            complement(14578..14787)
                     /locus_tag="RH288_002333"
     CDS             complement(14578..14787)
                     /locus_tag="RH288_002333"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031380.1"
                     /translation="MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQ
                     LTFLKGATAKNVRECNLMKNSVAEH"
     gene            14842..18804
                     /gene="putA"
                     /locus_tag="RH288_002334"
     CDS             14842..18804
                     /gene="putA"
                     /locus_tag="RH288_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HDV4031381.1"
                     /translation="MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQL
                     ENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRP
                     ETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGK
                     LVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEESDRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDL
                     ANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPR
                     EVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGS
                     TEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAG
                     QRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYN
                     RNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAKYPVDAQLKAALTQPLNAL
                     REWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDAL
                     TQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDS
                     DQLRALCEAVAARDGTIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            complement(18844..19482)
                     /gene="rutR"
                     /locus_tag="RH288_002335"
     CDS             complement(18844..19482)
                     /gene="rutR"
                     /locus_tag="RH288_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HDV4031382.1"
                     /translation="MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQI
                     AELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQ
                     HLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR"
     gene            19770..20861
                     /gene="rutA"
                     /locus_tag="RH288_002336"
     CDS             19770..20861
                     /gene="rutA"
                     /locus_tag="RH288_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309285.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein A"
                     /protein_id="HDV4031383.1"
                     /translation="MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDF
                     ALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAA
                     TIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKS
                     DFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFA
                     PTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQ
                     KDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDF
                     LSGIETFGERIQPLMQCRAHLPALTQEVA"
     gene            20861..21553
                     /gene="rutB"
                     /locus_tag="RH288_002337"
     CDS             20861..21553
                     /gene="rutB"
                     /locus_tag="RH288_002337"
                     /EC_number="3.5.1.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxyureidoacrylate/ureidoacrylate
                     amidohydrolase RutB"
                     /protein_id="HDV4031384.1"
                     /translation="MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVS
                     TTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQP
                     QLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTG
                     IATNVCVESTLRDGFFLEYFGVVLEDATHQAGPKFAQKAALFNIETFFGWVSDVETFC
                     DALSPTSFAHIA"
     gene            21565..21951
                     /gene="rutC"
                     /locus_tag="RH288_002338"
     CDS             21565..21951
                     /gene="rutC"
                     /locus_tag="RH288_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein C"
                     /protein_id="HDV4031385.1"
                     /translation="MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLF
                     ADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKP
                     ARFCIQCGLVKPDALVEIATIAHIAK"
     gene            21959..22759
                     /gene="rutD"
                     /locus_tag="RH288_002339"
     CDS             21959..22759
                     /gene="rutD"
                     /locus_tag="RH288_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein D"
                     /protein_id="HDV4031386.1"
                     /translation="MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVC
                     YDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYP
                     ASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPR
                     LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSS
                     ELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL"
     gene            22769..23359
                     /locus_tag="RH288_002340"
     CDS             22769..23359
                     /locus_tag="RH288_002340"
                     /EC_number="1.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonic semialdehyde reductase"
                     /protein_id="HDV4031387.1"
                     /translation="MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGP
                     TSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFP
                     HGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFT
                     GSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL"
     gene            23370..23864
                     /gene="rutF"
                     /locus_tag="RH288_002341"
     CDS             23370..23864
                     /gene="rutF"
                     /locus_tag="RH288_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415527.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization flavin reductase protein
                     F"
                     /protein_id="HDV4031388.1"
                     /translation="MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTD
                     TPPTLLVCLNRGASVWPAFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQT
                     GVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALM
                     RPAC"
     gene            23885..25213
                     /gene="rutG"
                     /locus_tag="RH288_002342"
     CDS             23885..25213
                     /gene="rutG"
                     /locus_tag="RH288_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization transport protein G"
                     /protein_id="HDV4031389.1"
                     /translation="MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMF
                     GATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNG
                     QGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
                     IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLG
                     LGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGR
                     NMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAML
                     LGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTL
                     VLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP"
     gene            complement(25470..25643)
                     /locus_tag="RH288_002343"
     CDS             complement(25470..25643)
                     /locus_tag="RH288_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDV4031390.1"
                     /translation="MANHRGGSGNFAEDRERASEAGKKGGQHSGGNFKNDPQRASEAG
                     KKGGKSSHGKSDN"
     gene            26016..26612
                     /gene="wrbA"
                     /locus_tag="RH288_002344"
     CDS             26016..26612
                     /gene="wrbA"
                     /locus_tag="RH288_002344"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HDV4031391.1"
                     /translation="MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMP
                     PQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            26633..26860
                     /locus_tag="RH288_002345"
     CDS             26633..26860
                     /locus_tag="RH288_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HDV4031392.1"
                     /translation="MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWE
                     EGSDEVLVKAFAKTDKDSLFWGEQTIERKNV"
     gene            complement(26898..28139)
                     /gene="agp"
                     /locus_tag="RH288_002346"
     CDS             complement(26898..28139)
                     /gene="agp"
                     /locus_tag="RH288_002346"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HDV4031393.1"
                     /translation="MNKTLIAAAVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECP
                     PPYTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQE
                     PGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTS
                     PEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNE
                     RTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCP
                     IDADGFCPMDKFDSVLNEAVK"
     gene            complement(28432..>29661)
                     /locus_tag="RH288_002347"
     CDS             complement(28432..>29661)
                     /locus_tag="RH288_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccE family protein"
                     /protein_id="HDV4031394.1"
                     /translation="CTANNYLKQAWNDIKNEYEKNQTYSITLFENTLVCFMRLYNELR
                     RKVNEEDTPCLECESLEKEFEEMQNDNDLSLFMRTLRTNDTQIYSGVSGGITYTIQYV
                     RDIDIVRVSLPGRASESITDFKGYYWYNFMEYIENINACDDVFSEYCFDDENISVQPE
                     RINTPGISDLDSDIDLSGISFIQRETNQALGLKYAPVDGDGYCLLRAILVLKQHDYSW
                     ALVSYKMQKEVYNEFIKMVDKKTIEALVDTAFYNLREDVKTLFGVDLQSDNQIQGQSS
                     LMSWSFLFFKKQFIDSCLNNEKCILHLPEFIFNDNKNLLALDTDTSDRIKAVKNFLAV
                     LSDSICSLFIVNSNVASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPPELFAQAYKL
                     NNKEMNAQLDYLNRYAI"
BASE COUNT         7478 a         7569 c         7277 g         7337 t
ORIGIN      
        1 gtgcaatgtt ctttgttact cgtagcgcac tgaatatatg gcacataaat attaccataa
       61 cggttaactt actgactact tcaatagtgc gactaatata ccaagtggac acgctatacc
      121 tgctcataaa taacagagag atattgtaca gtacggcaca aaaagcaatc accgtcactc
      181 cattccagat atcatagcgt aaaccattaa agtatagatt aaccgaaagc aaggttaacc
      241 acatgaaaat cattatggta acatatgagg ctttccaaac cacctgacca ttttcattgg
      301 ttaactcggc aatgtgtaaa ttgtagctct cataatgact agaaagtatg tgagcaacta
      361 tcggcccccc aaaaacaaaa aacaaactta tgcacaaagt catttttttg gaaaataaat
      421 tgcgctgttt tgtgttttca ctaactttat tcaccaatgc cagaaatatt aatatgcaca
      481 aactcatctg acgaaacaaa taatagattg caatgtcatt ttggacaaca ctgcttgtca
      541 aacgctcctc aataatttgc tgaatgataa tgacggttat aacaaagtaa atcaaacaac
      601 tcagaaaagc caaactaagt acacagtttg aaaattgcct acggtcataa atgaaataca
      661 actgcataaa aataaatgca acagtatcga taaaaaataa agcaatcatt accatcagat
      721 aggttgatcg tggaacaact tcctcaacgc ctggctgatt aaaccaacta ttcaccaaaa
      781 ccaaagcaag cccaaacaat aagctcacta atacagtact actaattctc aaatagtctt
      841 tttccataaa gctacaccaa tctgtaggtt gtagatccct ttctattatt aatagatata
      901 agaactgtac tgttgtcaat atgaaattcc gcccacaaac aataccgatg atgatagttg
      961 ctgaatgtaa ttattattgc ctaagtgctt tatacattgt ttgcaacaag ccaggcttga
     1021 aaatacttat aaatggttat agaaaatcct tataaaacat taattcatag atacattagg
     1081 aataacaatt aaatccgtga gtgccgtagc gcagcctttc atcaggactt tcgaaaaatc
     1141 cgaaatcatg catcggaatt tactgattta attattttaa tcctaattta ttttgaaaaa
     1201 ggcattggga tttatgccgt attcctgaag atcctcatca ttggaatgga ttttcgggcg
     1261 agaaaaggat tttatatgga cactctgctc atcatttctt cttctcatca tcaacaattc
     1321 acgtctctct tccgcgttta ataacggatt atgaggtgca aaaatatctt tcttttcagt
     1381 tacctgtaat tagatacaga gagagatttt ggcaatacat ggagtaatac aggatgtatt
     1441 caagtagcag aaaaaggtgc ccgaaaacca aatgggcttt gaaacttctt actgccgcat
     1501 ttttagcagc gagtcccgcg gcgaagagtg ctgttaataa cgcctatgat gcattgatta
     1561 ttgaagctcg caagggtaat actcagccag ctttgtcatg gtttgcacta aaatcagcac
     1621 tcagcaataa ccaaattgct gactggttac agattgcctt atgggccggg caagataaac
     1681 aggttattac cgtttacaac cgctaccgtc atcagcaatt accagcgcgt ggttatgcag
     1741 ctgtcgccgt cgcttatcgt aacctgcaac aatggcaaaa ctcgcttaca ctgtggcaaa
     1801 aggcgctctc tctggagccg caaaataagg attatcaacg gggacaaatt ttaaccctgg
     1861 cagatgctgg tcactatgat actgcgctgg ttaaacttaa gcagcttaac tctggagcac
     1921 cggacaaagc caatttactc gcagaagcct atatctataa actggcgggg cgtcatcagg
     1981 atgaattacg ggcgatgaca gagtcattac ctgaaaatgc atctacgcaa caatatccca
     2041 cagaatacgt gcaggcatta cgtaataatc aacttgctgc cgcgattgac gatgccaatt
     2101 taacgccaga tattcgcgct gatattcatg ccgaactggt cagactgtcg tttatgccta
     2161 cgcgcagtga aagtgaacgt tatgccattg ccgatcgcgc cctcgcccaa tacgctgcat
     2221 tagaaattct gtggcacgat aacccagacc gcactgccca gtaccagcgt attcaggttg
     2281 atcatcttgg cgcgttatta actcgcgatc gttataaaga cgttatttct cactatcagc
     2341 gattaaaaaa gacggggcaa attattccgc cctgggggca atattgggtt gcatcggctt
     2401 atctcaaaga tcatcagccg aaaaaagcac agtcaataat gaccgagctc ttttatcaca
     2461 aggagaccat tgccccggat ttatccgatg aagaacttgc ggatctcttt tacagccacc
     2521 tggagagtga aaattatccg ggcgcgctaa ctgtcaccca acataccatt aatacttcgc
     2581 cgcctttcct tcggttaatg ggcacgccta cgagcatccc gaatgatacc tggttacagg
     2641 ggcattcgtt tctctcaacc gtagcaaaat atagtaatga tcttcctcag gctgaaatga
     2701 cagccagaga gcttgcttat aacgcaccag gaaatcaggg actgcgcatt gattacgcga
     2761 gtgtgttaca agcccgcggt tggcctcgtg cagcagaaaa tgaattaaaa aaagcagaag
     2821 tgatcgagcc acgtaatatt aatctggagg ttgaacaagc ctggacagca ttaacgttac
     2881 aagaatggca gcaggcagct gtcttaacgc acgatgttgt cgaacgtgaa ccgcaagatc
     2941 ccggcgttgt acgattaaaa cgtgcggttg atgtacataa tcttgcagag cttcgtatcg
     3001 ctggctcaac aggaattgat gccgaaggcc cggatagtgg taaacatgat gtcgacttaa
     3061 ccaccatcgt ttattcacca ccgctgaagg ataactggcg cggttttgct ggattcggtt
     3121 atgccgatgg acaatttagc gaaggaaaag ggattgttcg cgactggctt gcgggtgttg
     3181 agtggcggtc acgtaatatc tggctcgagg cagagtacgc tgaacgcgtt ttcaatcatg
     3241 agcataaacc cggcgcgcgc ctgtctggct ggtatgattt taatgataac tggcgtattg
     3301 gttcgcaact ggaacgcctc tctcaccgcg ttccattacg ggcaatgaaa aatggtgtta
     3361 caggcaacag tgctcaggct tatgttcgct ggtatcaaaa tgagcggcgt aagtacggtg
     3421 tctcctgggc tttcactgat ttttccgaca gtaaccagcg tcatgaagtc tcacttgagg
     3481 gtcaggaacg catctggtct tcaccatatt tgattgtcga tttcctaccc agtctgtatt
     3541 acgaacaaaa tacagaacac gataccccat actacaaccc tataaaaacg ttcgatattg
     3601 ttccggcatt tgaggcaagc catttgttat ggcgaagcta tgaaaatagc tgggagcaaa
     3661 tattcagcgc aggtgttggt gcctcctggc aaaaacatta tggcacggat gtcgtcaccc
     3721 aactcggcta cgggcaacgc attagttgga atgacgtgat tgatgctggc gcaacgctac
     3781 gctgggaaaa acgaccttat gacggtgaca gagaacacaa cttatacgtt gaattcgata
     3841 tgacattcag attttaagga taaatatgtt acgtaatgga aataaatatc tcctgatgct
     3901 ggtgagtata attatgctca ccgcgtgcat tagccagtca agaacatcat ttataccgcc
     3961 acaggatcgc gaatctttac tcgccgagca accgtggccg cataatggtt ttgtagcgat
     4021 ttcatggcat aacgttgaag acgaagctgc cgaccagcgt tttatgtcag tgcggacatc
     4081 agcactgcgt gaacaatttg cctggctgcg cgagaacggt tatcaaccgg tcagtattgc
     4141 tcaaattcgt gaagcacatc gaggaggaaa accgctaccg gaaaaagctg tagtgctgac
     4201 ttttgatgac ggctaccaga gtttttatac ccgcgtcttc ccaattcttc aggccttcca
     4261 gtggcctgct gtatgggccc ccgtcggcag ttgggtcgat acgccagcgg ataaacaagt
     4321 aaaatttggc gatgagttgg tcgatcgaga atattttgcc acgtggcaac aagtgcgaga
     4381 agttgcgcgt tcccggctcg ttgagctcgc ttctcataca tggaattctc actacggtat
     4441 tcaggctaat gccaccggca gcttattgcc tgtatatgta aatcgtgcat attttactga
     4501 ccacgcacgg tatgaaaccg cagcagaata ccgggaaaga attcgtctgg atgctgtaaa
     4561 aatgacggaa tacctgcgta caaaggttga ggtaaatcca cacgtttttg tttggcctta
     4621 tggcgaagcg aatggcatag cgatagagga attaaaaaaa ctcggttatg acatgttctt
     4681 cacccttgaa tcaggtttgg caaatgcgtc gcaattggat tccattccgc gggtattaat
     4741 cgccaataat ccctcattaa aagagtttgc ccagcaaatt attaccgtac aggaaaaatc
     4801 accacaacgg ataatgcata tcgatcttga ttacgtttat gacgaaaacc tccagcaaat
     4861 ggatcgcaat attgatgtgc taattcagcg ggtgaaagat atgcaaatat caaccgtgta
     4921 tttgcaggca tttgctgatc ccgatggtga tgggctggtc aaagaggtct ggtttccaaa
     4981 tcgtttgcta ccaatgaaag cagatatttt tagtcgggtt gcctggcaat tacgtacccg
     5041 ctcaggtgta aacatctatg cgtggatgcc ggtattaagc tgggatttag atcccacatt
     5101 aacgcgagta aaatacttac caacagggga gaaaaaagca caaattcatc ctgaacaata
     5161 tcaccgtctc tctcctttcg atgacagagt cagagcacaa gttggcatgt tatatgaaga
     5221 tcttgccgga catgctgctt ttgatggcat attgttccac gatgatgctt tgctttcaga
     5281 ttatgaagat gccagtgcac cggctatcac ggcttatcag caagcaggct ttagcgggag
     5341 tctgagcgaa attcgacaaa acccggagca atttaaacag tgggcccgct ttaaaagtcg
     5401 tgcgttaact gacttcactt tagaacttag tgcgcgcgta aaagccattc gcggtccaca
     5461 tattaaaact gcacgaaata tttttgcact tccggtaata caacctgaaa gtgaagcctg
     5521 gtttgcacag aattatgctg atttcctaaa aagctatgac tggaccgcta ttatggctat
     5581 gccttatctg gaaggtgtcg cagaaaaatc ggctgaccaa tggttaatac aattgaccaa
     5641 tcaaattaaa aacatccctc aggctaaaga caaatctatt ttagaattac aggcacaaaa
     5701 ctggcagaaa aatggtcagc atcaggctat ttcttcgcaa caactcgctc actggatgag
     5761 cctattacaa ctgaatggag tgaaaaacta tggttattat cccgacaatt ttctgcataa
     5821 ccaacctgaa atagacctta ttcgtcctga gttttcaaca gcctggtatc cgaaaaatga
     5881 ttaatcgcat cgtatcgttt tttatattat gtctggtgtt atgcataccc ctatgcgtag
     5941 cgtactttca ctctggtgaa ctgatgatga ggttcgtttt cttctggccg ttttttatgt
     6001 ccattatgtg gattgttggc ggcgtctatt tctgggtcta tcgtgaacgc cactggccgt
     6061 ggggagaaaa cgcaccagct ccccagttga aagataatcc gtctatctcc attatcattc
     6121 cctgttttaa tgaggagaaa aacgttgagg aaaccataca cgccgcttta gcacagcgtt
     6181 atgagaacat tgaagttatt gccgtaaatg acggttcaac agataaaacc cgtgccatcc
     6241 tggatcgcat ggctgcacaa attccccatt tgcgggtcat tcatctggcg caaaaccagg
     6301 ggaaagccat tgcgcttaaa accggagctg ccgcggcgaa aagtgaatat ctggtgtgca
     6361 ttgatggcga tgcgttatta gaccgcgatg cggcggcata tattgtggaa ccgatgttgt
     6421 acaacccgcg tgtgggtgcc gtaaccggta atcctcgtat tcgaacacgt tctaccctgg
     6481 tgggtaaaat tcaggttggc gagtattcct caattattgg tttgatcaag cgaacccagc
     6541 gtatctatgg aaacgtattt accgtttccg gtgttattgc cgcatttcgt cgcagcgccc
     6601 tggcagaagt gggttactgg agtgacgata tgatcaccga agatattgat attagctgga
     6661 agctgcagtt gaatcagtgg acgatttttt acgagccacg ggcactgtgc tggatattaa
     6721 tgcctgaaac gttaaaaggg ctgtggaaac agcgcctgcg ctgggctcag ggcggtgcag
     6781 aagtattcct caaaaatatg acaaggttgt ggcgcaaaga aaactttcga atgtggccgc
     6841 tgttttttga atactgcctg acgacaatat gggccttcac ctgcctggtc ggtttcatta
     6901 tttacgcagt ccaacttgcc ggtgtaccgt taaatattga attgacacat atcgctgcga
     6961 cacatactgc cggaatatta ttgtgtacgt tatgtttact gcaatttatt gtcagcctga
     7021 tgatcgagaa tcgctatgag cataatctga cttcatcgct tttctggatt atttggttcc
     7081 cggttatttt ctggatgctg agcctggcaa cgacattggt atcatttaca cgagtcatgt
     7141 tgatgcctaa aaagcaacgc gcccgttggg taagtcccga tcgcgggatt ctgagaggtt
     7201 aatatgaaca atttaattat tacgacccga caatcaccag tacgtttact ggttgattat
     7261 gttgccacaa ccatcttgtg gacattattt gcgttgttca tattcttatt cgccatggat
     7321 ctgctgacgg gttattactg gcaaagcgag gccagaagcc gacttcagtt ctattttttg
     7381 ctggcagtgg cgaatgccgt cgtgttaatt gtctgggcgc tgtacaataa gctgcgtttt
     7441 caaaaacagc agcatcatgc agcctaccaa tatacgccgc aagaatatgc agagagctta
     7501 gcaatacctg atgagctcta tcagcaacta caaaaaagcc acaggatgag cgtacacttc
     7561 accagccagg ggcaaataaa aatggttgtt tcagaaaaag cgctagtccg ggcataaaca
     7621 cccaaaacaa agcccggttc gcccgggctc tgcaccgata acacacttaa ctgtaggcat
     7681 gcagcgtacg ttggcaaagt gccgaacgta cgcagtcctc tttaccgaac cggacgatcc
     7741 caaccatttc atcttcttcg aaacgttcca gcgcgtcact taatccggag cacacgccgc
     7801 gaggcaaatc gcattgcgtg atatcaccgt tgacgataac cgtcacgttc tccccgaggc
     7861 gggttaaaaa cattttcatt tgcgcggcag tcacattctg cgcctcgtca agaatgacga
     7921 ctgcattttc aaaggtacgt ccacgcatat aggcgaacgg cgcaatttcc accttcccta
     7981 tttccggtcg caggcagtac tgcataaagg aagcccctaa gcgccggacc agcacgtcgt
     8041 agaccgggcg aaaataggga gcaaactttt ctgcgatatc tccaggtaag aagccaagat
     8101 cttcatcggc ttgcagaact ggacgggtga cgataatcct gtcgacatcc ttatgtatca
     8161 gggcctctgc cgcttttgct gcgctgatcc aggtttttcc gcacccggct tcgcccgtgg
     8221 cgaatatcag ctgcttactc tcaatagcct tcagatagtg caattgcgct tcatttcgcg
     8281 cgaggatggg cgaagtatcg cgactgtcgc gggccatacc aatggcttct acgccgccca
     8341 tctgcacaag cgaggtgacc gattcttctt cacgctgctt atggctgcgc gaatcccgtc
     8401 tcagcacacg ttttgcctcg cgacgagctt tgatcactgc tttttgtctt cccatggaga
     8461 gcaccttgag ttgtttgtat tcatcacacg cgccgttggc agcgcgatta tgcgcacgaa
     8521 catcagaggg ttggcttcct tgtaagccat agtttgcttt tggataaaat gccgaaaaac
     8581 ggctacgcgc accgtttacg gcgtcggtaa cacatgaaaa gaaaggatga ggttgaaaat
     8641 gcaaagtgac gagatgacta ccggaggaga aaactccgcg agtggtggcg cgttgattat
     8701 ctaaaacatg tccagtacag gacgttacca tccgcgatct ccatagtgac tgactatcac
     8761 tgccgggaac ttccgctgct acttaataag tacaacagat ctcgcattta ttgcaacaat
     8821 atatttactt atatttaact ataaaacacc atttcagtga cattagtttc tactggaaag
     8881 atgacagagt gatgacagtg atgaaaaaag ctgtgtgctt tcagcaggat ttgcatcagg
     8941 catcagtgca cgatcgccgg atgcggcgtg aacgccttat ccagcctacc aaacccgcac
     9001 tgattgtagg catgataaga cgcgcaagcg tcgcatcagg catctgcgca caaatgcctt
     9061 atccgcctaa aaacattaaa cccgcaataa cgcgcttccg aaataatcgt tcgcgtcctt
     9121 cacccccggc agcgcaaaaa aataaccgcc gccgataggt ttaacgtatt cctccagcgc
     9181 ttcgccattg agcctttttt gtactgtcag gaagcctttt tccagatcgt gttggtagca
     9241 gacaaacagc aaccccatat ccagttgccc ggagttggtg acgcccagtg aataactgta
     9301 gccacgacgc agcatcaggc tggactcact ctccgccgtg cggggattcg ccagccggat
     9361 atggctgtcc agcgcgatca ccttcccttc cgggtcgctg gcgtaatcag gcacatcatg
     9421 ctcatgctgc attcccagcg gcgcaccggt ttgcttatca cggccaaaaa tcgtctgctg
     9481 ttctttcagc ggcgttctgt cccaaaattc cactcgaaac tgaatcaagc gtactgcctg
     9541 atagctgcca ccgattgtcc acgcaggctc ctgctgatct gccgttaccc acaccacttt
     9601 ttgcatcaac ttatcattct ggctatcggg attggcagtg ccgtctttga aacccagcaa
     9661 attaatcggc gtctctttgc ctttactacg cgccgcgtga tcggaaataa acccttcccg
     9721 cttccagcgc acactgagca aatccggcgt gtgtttgatg atatcgcgca gcgcatggat
     9781 aaccgtgtcc tgggtgttgg cgcaaatctg tagcaacaca tcaccatgac ataacgctgc
     9841 atccagcgag tcgttgggga aacgcgtcat cttctgcagc ttttttggca tctgtggcgc
     9901 aaggccaaag cgctcatcaa acaatgagtg acccaccgat aacgtgatgg tgagattatc
     9961 gggcgcaatg tagccgccaa gaatgccgga atcgagtggt ggcaggcgcg gatttggcgt
    10021 ttctggtgct gctccgccct gagtcagaaa agcaaaacgc tgagtcaaca agcgaaacaa
    10081 ccgctcaaga tcggctttat cgctggcaag cacatcaaac gccaccagca tcattgcggc
    10141 ctgttgtggc gtcaggatcc ctgcctgatg ctcaccataa aacggctgtt tctcattgcg
    10201 agcatccggt gaaagcgtac ccggcgcact ttgcgttttt tgtgcatgag cgaccggaca
    10261 acttcccgcc agcgccagtg cacctatcac tttcagtaaa cgtcggcgtg acggttcatt
    10321 cacgccgttt tcatctttat actgcataac gcttaatcca gtcccagcac accgcgaagt
    10381 tgcgccagat cttccgccag cgcagtaatc ggtcctttca gtgcattccg gtcggcatcg
    10441 gtcaatttgt cgtaggtttc aaaaccgtct ttagtacggt atttcgccag aatggtatcg
    10501 acctttttaa agttggcatc gacttttgcc agcagttccg ggttggcttt ttgcagttgt
    10561 ggacgcagca aatcgacaat tttctgcgag ccttcaacgt tagcctggaa atcccacaga
    10621 tcggtgtggc tgtagcgatc ttcttcaccg ctaattttgc tggctgccac ttcctcaatc
    10681 agtccggctg cgccgccgac cacttttgaa ggtgggaaag ccagttcact gatgcgtttt
    10741 tgcaaatcga ccacatcggt ataaagctgc tcagcgtact gatccatccc tttggtggtg
    10801 ttgtcgccaa acaatgcttt ttccagacgg tggaaaccag tgaattttgg gtcggcggct
    10861 ttttgctcgt aatcatcttc acgggcgtca atgctgccat ccagatcgga gaacagttca
    10921 gcaatcggtt caatacgctc atagtgctgg cgcgtcggtg catacagtgc tttcgctttt
    10981 tcgatatcgc ctgctttaat cgcgtcggta aaggctttgg tgtcggtcac cagctgcgtg
    11041 gtttccgcca tgacatacgc tttatatgca gtaattgcac caccaagact taacagcgca
    11101 tcactttgcg ccgcatccgc cgttgcctca cctttgacga tcaacttccc tttcgggtta
    11161 gtcagcagac cgcaggtcat atcgtattcg ccaggctgta aattcgccgt cattttctgg
    11221 ctaaagccag gggcgatatt ttcccgctct tccaccacca tcacgccttt gaggatctcc
    11281 cactccagcg ccttctgact gtggttctga ataatgaact gtgttttccc ggcgttaacc
    11341 gtaatggtca tcggttcgca ctgcttatcc gtcacggtca ctttgacctg cggcacatca
    11401 gcggcgttag ccataaaagc agaagaaaac agcgcagcca cgctcaactg caatgcgtta
    11461 cggcggaagt taatggtcat gacgagacta tccctttaaa gtatgttgta actaagcaag
    11521 agtttgcgtc gtatttgtta cgcggagcga gacgctgtcg cccctgcgcg tggtggcaga
    11581 gcaaatgcca ccagcgccgg gatgagataa ataaaccaga cggcgacttc gctgacgctc
    11641 ggcgcttcct gatagccaaa aatcccttcc atcagcgtgc caaacagcga gtgagttgag
    11701 agcaccgcac tcatatcgaa ggcgatttcc tgaaagtggt tccacaatcc ggcttcatga
    11761 aatgcgcgaa tggcaccagc tgccagccct gcggcgacga agagaataaa caggctggtc
    11821 catttaaaaa atgcaccaag attgaggcga ataccgcccc agtagagcag gaagcctagc
    11881 accacggcag tagcaagacc gagcattgca cccagcggcg gccagatccc gacatcttgt
    11941 tgaaatgccg ccagcaggaa aaagaccgac tccagccctt cccttgcaac ggcaaaaaag
    12001 accatcatca ccagcgccca gccatgatga tttccacgct gcaatgcgct atcgactgcc
    12061 tgttccagtt gcactttgac gttgcgcgac actttgcgca tccagaaaac catccaggta
    12121 aggatcacca cggcgatcac cgccacgata ccttcaaaca gttcctgttc tttttgcgga
    12181 aattcgccgg tggtttcgtt aatgaagata cccaagccca ggcacaacgc agcggcaagc
    12241 aacacgccaa tccacatcac accaatccat cggcctcgct gggtacgctt aagatagctg
    12301 gcaatcaaac tgacaatcag cgcggcttca agtccttcgc gcaacataat gagaaacgga
    12361 acaaacatgc cacccaccct taaacgtttt tctgagtcaa tctatgcaaa gaaaagtaaa
    12421 tcgcagtgat agcgattatc attacggcaa agaaaaacac aagcggaatg tttataaaat
    12481 gatgttggaa tgtaaacaaa gagaggtaat gccaagggat ataaacgatt attccagggt
    12541 agaaagatgg gattgtttgc aaagaaccat gtgttcttgc cggatgccgc gtaaacgccg
    12601 tatccagccg acaaaactgt ccagactcaa tgcatcagag cttccatgta aaactgataa
    12661 gcgggtgtat caagcaattt cgtccatccg cgattatcaa atctaacttt ttgcccggaa
    12721 cataataaca gctcgggtgt tggtggcgtc aaaatcgctg aagcgttccc cgaaggccgg
    12781 gacagcaggg ggcggcggcg attggccgcc ccctgcgcgc tccctgcacc attcaattta
    12841 tatggcgagg cacattaagg gagcgcaacc cgctgctgaa gccaaacaaa accgccgcag
    12901 gctaagtccc ttagctttcc tgcaaccgtg acggcggagc cgaatgatag tgcgcatcgg
    12961 cctcggcaaa gcgtttttgc atcgccgctg acggcgcttt acccagcaaa ctaaacacta
    13021 caatcccaat actgccgaag ataaagcccg gaataatttc gtacagtccc agccagccga
    13081 actgtttcca gacgataacc gtcagcgcac cgatgatcat ccccgccagc gcaccgttac
    13141 gcgtcatgcg tgaccacatc accgagaaca gcaccactgg accaaacgcc gcgccaaagc
    13201 ctgcccacgc gtagctcact aagcccagca cgcggttttc cgggtttgcc gccagcgcaa
    13261 tcgccaccag cgccaccacc agcaccatca cacgccctac ccacaccagc tctttctggc
    13321 tggcatgttt acgcagaaac gctttgtaca aatcttcggt aatcgcactg gagcacacca
    13381 gcagctggca acttaaggtt gacattaccg ccgccagaat tgccgacagc agaatcccgg
    13441 caatccacgg gttaaacaga atttgcgcca gttcgataaa cacacgctcg gcgttctgat
    13501 ttaccgcacc agccaacgcc ggatgatcgt taaagtaagc aatcccaaag aagccgacag
    13561 ccaccgcccc tgccaggcag aggatcatcc aggtcatact aatacgacgc gcatggacaa
    13621 tgctgtggtg agaatccgcc gccataaaac gcgccagaat gtgcggctgc ccgaagtaac
    13681 ccagccccca acccatcagt gagataatgg caacaaagtt cagacctttg agcatatcaa
    13741 cgttttcgat gctcttttgt ttgatcactt ccagcgagtc accaaagcca ccgacactga
    13801 taatgacgat aaccggcgtc aggatcaggg caaaaatcat caggctggcc tgtacagtgt
    13861 cagtccagct caccgcgagg aaaccgccaa taaaggtgta aaggatcgtc gccgcagcgc
    13921 ccgcccacag agccgtttcg tagctcatgc caaaggtact ttcaaacaga cgcgcgcctg
    13981 ccacaatgcc cgaagcgcaa taaatggtga agaacagcaa aataaccagc gcagagataa
    14041 tgcgcaaaat gcggctttta tcttcaaagc gcccggtgaa ataatccggc agtgttaagg
    14101 cgttattgtt gtattcggta tgcacacgca accgcccggc caccagcttc cagttaatcc
    14161 acgcgcctaa tgtcaggcca atggcgatcc agctttcgga aatcccggaa agaaaaacag
    14221 cgcccggcaa ccccattaac agccagccgc tcatatccga cgcacccgcc gataatgccg
    14281 tcacgaatgg cccaagacta cgaccgccca gaatatagtc gtcaaagttt ttcgttgatc
    14341 gccaggcgat aaacccaatc aatatcatgc caaagatata gacacaaaat gtcaccaaca
    14401 tcggtgtgct aatagccatc taaagtctcc aaaaaattat tatcggcaat gtcgaaactt
    14461 gccgttatat ctgccaccgg aacggggtaa cagagtttat gttttaccag ggcgaccgta
    14521 tcctgccgga agcgctggtt attcacaatc gatttaacac accatttaca ttaaatttta
    14581 gtgctcagcg acactatttt tcatcaggtt gcactctctc acattttttg cggttgcacc
    14641 tttcaaaaat gttaactgcc gcagagaaaa agtctgagtt atttttttaa tccctgtcat
    14701 atcgatttct tttattaaca tttcattcat ttttaagctt gctacgcatg tcacatttaa
    14761 catggttgca caaagttgca acatcatgga tatttcacga taacgttaag ttgcaccttt
    14821 ctgaacaaca ggagtaatgg catgggaacc accaccatgg gggttaagct ggacgacgcg
    14881 acgcgtgagc gtattaagtc tgccgcgaca cgtatcgatc gcacaccaca ctggttaatt
    14941 aagcaggcga ttttttctta tctcgaacaa ctggaaaaca gcgatactct gccggagcta
    15001 cctgcgctgc tttctggcgc ggccaatgag agcgatgaag caccgactcc ggcagaggaa
    15061 ccacaccagc cattcctcga ctttgccgag caaatattgc cccagtcggt ttcccgcgcc
    15121 gcgatcaccg cggcctatcg ccgcccggaa accgaagcgg tttctatgct gctggaacaa
    15181 gcccgcctgc cgcagccagt tgctgaacag gcgcacaaac tggcgtatca gctggccgat
    15241 aaactgcgta atcaaaaaaa tgccagtggt cgcgcaggta tggtccaggg gttattgcag
    15301 gagttttcgc tgtcatcgca ggaaggcgtg gcgctgatgt gtctggcgga agcgttgttg
    15361 cgtattcccg acaaagccac ccgcgacgcg ttaattcgcg acaaaatcag caacggtaac
    15421 tggcagtcac acattggtcg tagcccgtca ctgtttgtta atgccgccac ctgggggctg
    15481 ctgtttactg gcaaactggt ttccacccat aacgaagcca gcctctcccg ctcgctgaac
    15541 cgcattatcg gtaaaagcgg tgaaccgctg atccgcaaag gtgtggatat ggcgatgcgc
    15601 ctgatgggtg agcagttcgt cactggcgaa accatcgcgg aagcgttagc caatgcccgc
    15661 aagctggaag agaaaggttt ccgttactct tacgatatgc tgggcgaagc cgcgctgacc
    15721 gccgcagatg cacaggcgta tatggtttcc tatcagcagg cgattcacgc catcggtaaa
    15781 gcgtctaacg gtcgtggcat ctatgaaggg ccgggcattt caatcaaact gtcggcgctg
    15841 catccgcgtt atagccgcgc ccagtatgac cgggtaatgg aagagcttta cccgcgtctg
    15901 aaatcactca ccctgctggc gcgtcagtac gatattggta tcaacattga cgccgaagag
    15961 tccgatcgcc tggagatctc cctcgatctg ctggaaaaac tctgtttcga gccggaactg
    16021 gcaggctgga acggcatcgg ttttgttatt caggcttatc aaaaacgctg cccgttggtg
    16081 atcgattacc tgattgatct cgccacccgc agccgtcgcc gtctgatgat tcgcctggtg
    16141 aaaggcgcgt actgggatag tgaaattaag cgtgcgcaga tggacggcct tgaaggttat
    16201 ccggtttata cccgcaaggt gtataccgac gtttcttatc tcgcctgtgc gaaaaagctg
    16261 ctggcggtgc cgaatctaat ctacccgcag ttcgcgacgc acaacgccca tacgctggcg
    16321 gcgatttatc aactggcggg gcagaactac tacccgggtc agtacgagtt ccagtgcctg
    16381 catggtatgg gcgagccact gtatgagcag gtcaccggga aagttgccga cggcaaactt
    16441 aaccgtccgt gtcgtattta tgctccggtt ggcacacatg aaacgctgtt ggcgtatctg
    16501 gtgcgtcgcc tgctggaaaa cggtgctaac acctcgtttg ttaaccgtat tgccgacacc
    16561 tctttgccac tggatgaact ggtcgccgat ccggtcactg ctgtagaaaa actggcgcaa
    16621 caggaagggc aaactggatt accgcatccg aaaattcccc tgccgcgcga tctttacggt
    16681 cacgggcgcg acaactcggc agggctggat ctcgctaacg aacaccgcct ggcctcgctc
    16741 tcctctgccc tgctcaatag tgcactgcaa aaatggcagg ccttgccaat gctggaacaa
    16801 ccggtagcgg caggtgagat gtcgcccgtt attaaccctg cggaaccgaa agatattgtg
    16861 ggctatgtgc gtgaagccac gccgcgtgaa gtagaacagg cgctggaaag tgcggttaat
    16921 aacgcgccaa tctggtttgc cacgcctccg gctgaacgcg cagcgatttt gcaccgcgct
    16981 gccgtgctga tggaaagcca gatgcagcaa ctgattggta ttctggtgcg tgaggccgga
    17041 aaaaccttca gtaacgccat tgccgaagtg cgcgaagcgg tcgattttct ccactactac
    17101 gccggacagg tgcgggatga tttcgctaac gaaacccacc gtccattagg gcctgtggtg
    17161 tgtatcagtc cgtggaactt cccgctggct attttcaccg ggcagatcgc cgccgcactg
    17221 gcggcaggta acagcgtgct ggcaaaaccg gcagaacaaa cgccgctgat tgccgcgcaa
    17281 gggatcgcca ttttgctgga agcgggtgta ccgccaggcg tggtgcaatt gctgccaggt
    17341 cggggtgaaa ccgtgggcgc gcaactgacg ggtgatgatc gcgtgcgcgg ggtgatgttt
    17401 accggttcaa ccgaagtcgc tacgttactg cagcgcaata tcgccagccg cctggacgct
    17461 cagggtcgcc ctattccgct catcgctgaa accggcggca tgaacgcgat gattgtcgat
    17521 tcttcagcac tgaccgaaca ggtcgtcgtg gatgtactgg cctcggcgtt cgacagtgcg
    17581 ggtcagcgtt gttcggcgct gcgcgtgctg tgcctgcaag atgagattgc cgaccacacg
    17641 ttgaaaatgc tgcgcggcgc aatggccgaa tgccggatgg gtaatccggg tcgcctgacc
    17701 accgatatcg gtccagtgat tgatagcgaa gcgaaagcca atattgagcg ccatattcag
    17761 accatgcgta gcaaaggccg tccggtgttc caggcggtgc gggaaaacag cgaagatgcc
    17821 cgtgaatggc aaagcggcac ctttgtcgcc ccgacgctga tcgaactgga tgactttgcc
    17881 gaattgcaaa aagaggtctt tggtccggtg ctgcatgtgg tgcgttacaa ccgtaaccag
    17941 ctaccagagc tgatcgagca gattaacgct tccggttatg gtctgacgct tggcgtccat
    18001 acgcgcattg atgaaaccat cgcccaggtc actggctcgg cccatgttgg taacctgtat
    18061 gttaaccgta atatggtggg cgcagtggtt ggtgtgcagc cgttcggcgg cgaagggttg
    18121 tccggtaccg ggccgaaagc aggcggtccg ctctatctct accgtctgct ggcgaatcgc
    18181 ccggaaagtg cgctggcagt gacgctcgcg cgtcaggatg caaagtatcc ggtcgatgcg
    18241 cagttgaaag ccgcattgac tcagccgcta aatgcactgc gggaatgggc agcaaatcgt
    18301 ccagaattgc aggcgttatg tacgcaatat ggcgagctgg cgcaggcagg aacacaacga
    18361 ttgctgccgg ggccgacggg tgaacgcaac acctggacgc tgctgccgcg tgagcgcgtg
    18421 ttgtgtattg ccgatgatga gcaggatgcg ctgactcagc tcgccgccgt gctggcggtg
    18481 ggcagccagg tactgtggcc ggatgacgcg ctgcatcgtc agttagtgaa ggcattgcca
    18541 tcggcagtca gcgaacgtat tcaactggcg aaagcggaaa atataaccgc tcaaccgttt
    18601 gatgcggtga tcttccacgg tgattcggat cagcttcgcg cattgtgtga agcagttgcc
    18661 gcgcgggatg gcacaattgt ttcggtgcag ggttttgccc gtggcgaaag caatatcctt
    18721 ctggaacggc tgtatatcga gcgttcgctg agtgtgaata ccgctgccgc tggcggtaac
    18781 gccagcttaa tgactatagg ttaaacaggt agccggagga tgttacaacc tcctccggca
    18841 tctttaacgt ggtcgaatcc cctcaataat aatccgctgc acgttttcaa ccgtttgatt
    18901 gaaaaatacc tcatcgcgca acgtcgcgcc tgtcaccgcc tccacctgag gggcgaaatc
    18961 ggcgtaatgt tgagtggaag cccaaatcat aaaaatcaaa tgctgcggat caatcggcgc
    19021 gagtttgccg cttttgaccc aaccggcaat cagcgccgat ttctcatcaa ttaatgcctt
    19081 caaatcgccc gtcagttcat ccattaacag cggcgcgcct gccagcatct ccatacagaa
    19141 caggcgcgaa gcctgcggat aatcgcgtga gacttccagc ttcagacgga tgtactcttt
    19201 gatcgccgcc agcggggcga aatcttcacg aaacgctttt aacggtgcca gccagatatc
    19261 gagaatctgc cgcagcacgg caatatacag cgcctctttt gacggaaagt aatacagcag
    19321 attggttttt gaaacacccg ccaactctgc gatctgctcc agccttgtgc cgtgaaaacc
    19381 gaattgtgaa aaagtgtcca gtgctgcgct aagaatcgct tttttcttcg cgcttactgc
    19441 gcgcgaacgt ttacccgttg ttttcactgc gccttgcgtc atgcgctctc ccctcttgta
    19501 gattggcaac aggatagcaa aacccccgcc cggcctcgac cttctgcact ctcatcgcgc
    19561 acagatgcat gttttatgtg caactgtttt gaccgtttag tccacttttt accagatatt
    19621 ttagataacg taatgttaac agattaataa cattaacttt ttaaaaactg gcatccgctt
    19681 tgcaaacaag ccaatacgcg gctgaaaagg atatgcagga tgcagcgccc cgtctgactt
    19741 tcactttacg agacgaagag aggttgatga tgaaaattgg cgtattcgta cctattggca
    19801 acaacggctg gctcatttcg acccacgcgc cgcagtacat gccgaccttt gaactgaata
    19861 aagccattgt gcaaaaagcg gagcactacc atttcgattt cgccctgtcg atgatcaaac
    19921 tgcgtggctt tggcggcaaa actgagttct gggatcacaa ccttgagtcg ttcaccttga
    19981 tggcggggct ggcggccgtg acctcgcgca ttcagattta cgccactgct gccaccttaa
    20041 cgttacctcc ggcaatcgtc gcccgtatgg ccgcaaccat cgactccatc tctggcgggc
    20101 gttttggcgt caacctcgtg actggctggc aaaagcccga gtatgagcag atgggtatct
    20161 ggcctggcga tgactatttc tcccgtcgtt acgactatct caccgaatat gttcaggtgc
    20221 tgcgcgacct gtggggcacg gggaaaagcg attttaaagg cgattttttc accatgaatg
    20281 attgtcgcgt gagtccgcaa ccgagtgtcc ccatgaaagt gatctgcgcc gggcaaagcg
    20341 acgctggcat ggcgttctcc gcccggtatg ccgatttcaa cttctgtttc ggcaaaggcg
    20401 taaatacacc cacggctttc gccccgaccg ctgcgcggat gaaacaggcc gcagagcaaa
    20461 ccggacgcga cgttggctct tatgtgttgt ttatggtgat tgccgatgaa accgacgatg
    20521 ccgctcgcgc caaatgggaa cactacaaag cgggcgcgga tgaagaggcg ttaagctggc
    20581 taaccgaaca aagtcagaaa gatacccgct ccggtactga caccaacgtt cgtcagatgg
    20641 ccgatcccac ttcggcggta aacatcaata tggggacgtt agtcggttct tacgccagtg
    20701 tcgcgcgcat gttagatgaa gtcgcaagcg tgcctggtgc cgaaggcgtg ctgttaacct
    20761 tcgacgattt tctgtcggga atcgaaacct tcggcgagcg cattcaacca ctgatgcaat
    20821 gccgcgccca tctacctgcg ctgactcagg aggtggcatg atgacgacct taaccgctcg
    20881 accggaagcc attaccttcg atccgcagca aagtgcgctg atcgtggtgg atatgcaaaa
    20941 cgcttatgcc acgccaggcg gctacttaga tctcgccggg tttgatgtct caaccactcg
    21001 cccggtcatt gccaacattc aaaccgccgt gaccgcagcg cgagcggcag ggatgctgat
    21061 catctggttt caaaatggct gggatgaaca gtatgtcgag gctggcggac ccggctcacc
    21121 gaattttcat aaatcgaacg ccctgaaaac catgcgtaag cagccgcagc tgcaggggaa
    21181 attgctggcg aaaggctcct gggattatca actggtggat gaactggtgc cgcagcctgg
    21241 cgatattgtg ctgccgaagc cgcgctacag cggtttcttc aatacgccgc tggacagcat
    21301 tttgcgcagc cgcggaatac gccatctggt tttcaccggc atcgctacca acgtctgcgt
    21361 cgaatcgacg ctacgcgacg gcttttttct ggagtatttc ggcgtggtgc ttgaagacgc
    21421 aactcaccag gcggggccga aatttgcgca gaaagccgcg ttgttcaata tcgaaacctt
    21481 ttttggctgg gtcagcgacg tcgaaacatt ctgcgacgcg ctttctccca cgtcctttgc
    21541 tcatatcgct taaggagttt aacgatgcca aaatccgtaa ttattcccgc tggcagcagc
    21601 gcaccgctgg cccccttcgt tcccggcacg ctggctgatg gcgtggtgta tgtctccggt
    21661 acgctggctt ttgatcaaca taataacgtg ctgtttgccg atgacccaaa ggcgcaaacc
    21721 cgccacgttc tggaaactat ccgcaaggtg atcgagacgg cgggtggcac gatggcggat
    21781 gtgaccttca acagcatctt tattaccgac tggaaaaatt acgccgcgat taacgaaatc
    21841 tacgccgagt tttttccggg tgataaaccg gcgcgattct gcattcagtg cggactggta
    21901 aaacctgacg cgctggtgga aatcgccaca attgcgcata tcgccaagtg aggccgcgat
    21961 gaaactttca ctctcacctc ccccttatgc tgatgcgccc gtagtggtgt tgatttcggg
    22021 tcttgggggt agcggcagtt actggttacc gcaactggcg gtgctggagc aggagtatca
    22081 ggtagtctgt tacgaccagc gcggcaccgg caataatccc gacacgctgg cagaagatta
    22141 cagtatcgcc cagatggcag cggaactgca tcaggcgctg gtagccgcag ggattgagca
    22201 ttacgcagtg gtcggccatg cgctcggtgc gctggtggga atgcagctgg cgctggatta
    22261 tcccgcgtcg gtaactgtgc tgatcagcgt taacggctgg ctacgaataa acgcccatac
    22321 gcgccgctgt tttcaggttc gcgaacgatt actgtatagc ggcggcgcgc aggcatgggt
    22381 ggaagcgcag ccgttgttcc tctatcccgc cgactggatg gcggcccgcg cacctcgcct
    22441 ggaggcagaa gacgcgctgg cactggcgca ttttcagggc aaaaataatt tactgcgtcg
    22501 acttaacgcc ctcaaacgcg ctgactttag tcaccatgcg gatcgcatcc gctgcccggt
    22561 gcaaatcatc tgcgccagtg atgatctgct ggtgccaaca gcatgttcca gtgaacttca
    22621 tgccgccctg cccgatagcc agaaaatggt gatgccctat ggcggacacg cctgcaacgt
    22681 gaccgatccc gaaacgttta atgctctgtt actcaacggg cttgccagcc tgttacatca
    22741 ccgtgaagcc gccctgtaag gaattgctat gaacgaagcc gttagcccag gtgcgcttag
    22801 caccctgttc accgatgccc gcactcacaa cggctggcgg gagacacccg tcagcgatga
    22861 gacgttacgg gagatttatg ccctgatgaa atgggggccg acatcagcta actgttctcc
    22921 ggcacggatc gtgtttaccc gcacggcaga aggaaaagaa cgtctgcgcc cggcactttc
    22981 cagcggcaat ctgcaaaaaa ccctgaccgc gcccgtcacc gctatcgtcg cctgggacag
    23041 tgaattttat gaacggttac cactactgtt tccccacggt gatgcccgca gttggtttac
    23101 ctccagccca caacttgccg aagaaacagc gtttcgcaac agttccatgc aggcggccta
    23161 tctgatcgtc gcctgccggg cgctgggact ggataccggc ccgatgtcgg gctttgaccg
    23221 tcaacacgtg gacgacgcct tttttacggg cagcacgctg aagagcaatc tgctgattaa
    23281 tatcggctat ggcgatagca gcaagcttta tgcgcgcctg ccacgtctgt cctttgaaga
    23341 agcctgcggg ctgttgtaag gagcaaacta tgaacattgt cgatcaacaa acttttcgcg
    23401 atgcgatgtc ctgtatgggc gcggcggtca atattatcac cacggacggt ccagccgggc
    23461 gcgccgggtt caccgccagc gccgtctgca gtgtgaccga tacgccgccc acattactgg
    23521 tgtgcctgaa tcgtggggcg tccgtctggc cggcattcaa tgaaaatcga acgctgtgtg
    23581 taaatacact tagcgccggg caggagccgc tttcaaacct ttttggcggc aaaacgccca
    23641 tggaacaccg ctttgccgcc gcccgctggc agacgggggt gaccggatgc ccgcaactgg
    23701 aagaggctct ggtttcgttt gactgccgta tcagccaggt ggtgagcgtc ggcacccacg
    23761 acattctgtt ttgcgccatc gaagcgattc atcgtcacac cacaccctac gggctggtgt
    23821 ggttcgatcg cagttatcac gcgctgatgc gccctgcttg ttaacctcct taaggagaca
    23881 gctgatggca atgttcggtt ttcctcactg gcagttaaaa tcgacctcta cagagagcgg
    23941 cgtggtcgcg ccggatgaac gattgccgtt tgctcagacg gcagtaatgg gcgttcaaca
    24001 cgcggtggcg atgtttggcg cgacggtgtt aatgccgatt ctgatggggc tggatcccaa
    24061 tctttccatt ttaatgtcgg ggatcggcac gttactgttt ttctttatta ccggcgggcg
    24121 cgtccccagt tatctcggct ccagcgcggc ttttgtcggc gtggtgatcg ccgcgacggg
    24181 ctttaacggt cagggcatta acccgaatat cagcattgcg ctgggcggga ttatcgcctg
    24241 tgggctggtt tataccgtca ttggcctggt ggtgatgaaa atcggtacgc gctggattga
    24301 acgactgatg ccgccggtgg tgacgggtgc ggtggtgatg gcgattggcc tgaacttagc
    24361 gcctatcgca gtgaaaagtg tatcggcttc ggcctttgat agctggatgg cggtaatgac
    24421 ggtgctgtgt attgggctgg tggcggtgtt tacccgtggc atgatccagc ggttattgat
    24481 tctcgtagga ttaattgtcg cctgtctgct gtatggcgtg atgaccaacg ttttagggct
    24541 gggaaaagcc gtcgatttta ctctcgtcag ccatgctgcc tggttcggtc tgccacattt
    24601 ttccactcct gcttttaatg gtcaggcaat gatgctgatt gcgcccgtgg cggtgattct
    24661 ggtggcggaa aacttaggtc atctcaaggc agtcgccggg atgaccggac gcaatatgga
    24721 cccgtatatg gggcgggcat tcgtaggcga tggtctggca acgatgcttt ccggctctgt
    24781 cggcggtagc ggcgtgacca cctatgctga aaatatcggt gtgatggccg tgaccaaagt
    24841 ctactcgacg ctggtgtttg ttgctgctgc cgtcatcgcc atgctgttgg gcttttcacc
    24901 gaaatttggt gcgctgattc ataccattcc ggccgcggtt attggtggtg catcaattgt
    24961 tgtgttcggg ctgattgccg tcgcaggcgc aaggatatgg gtacaaaacc gtgtcgattt
    25021 aagccagaac ggtaatttga ttatggtcgc agtaacctta gtgctgggcg cgggtgattt
    25081 tgctctcacg ctgggcggtt ttacgttggg agggattggt acagcaacct ttggcgcgat
    25141 tttactcaat gcgttgttaa gcagaaagtt ggttgacgtt ccaccgccag aagttgttca
    25201 tcaggagcca taaacagaaa accgccgggg ttaccggcgg tgcagattgt tgacaacgta
    25261 cgcattgttc atgccggatg cggcgtaaac gccttatccg gcctacaaaa cagtgcaaat
    25321 tcaatatatt gcaatcttct ggtaggcctg ataagcatcg cgcatcaggc aagcttacat
    25381 ttgtcatcag tatcaaccac cgggtaaccg gcggtgatgg ctttttgacg agctacagac
    25441 aaaaatgcat tcgtcattga ttagcccggc tagttgtcgc ttttgccgtg actgctctta
    25501 ccaccttttt tacctgcttc agatgcgcgc tgcgggtcat tcttgaaatt acccccgctg
    25561 tgctgtccac cttttttacc tgcttctgat gctctttcgc ggtcttctgc aaaattgccg
    25621 gaaccgcctc gatggtttgc cattactgac ctccgtctgg gtatagacat catattgcat
    25681 agaattaacg cggcgtatgg cggctgccat attttcgcta cgtgggacta agcttagtga
    25741 actgacgcgg gcagacccgc gtttggtaat atcctgcaac agcttcttag cgagaataga
    25801 tatcatctcc aataattatc cataagccgc tcttatgatt aaaaaaacgc gatgagataa
    25861 aaatgtgtca ttttgcgaca aaattacgtg cttgtgaaag ttgttataaa tcaaataagt
    25921 ggttgtgaaa tttgcactct gaaaaggacg tcttatcttt aaataagtgg tagcgaatcg
    25981 ctacggaata gagataacac gaggagtggt tagaaatggc taaagttctg gtgctttatt
    26041 attccatgta cggacatatt gaaacgatgg cacgcgcagt cgctgagggt gcaagcaaag
    26101 tggatggcgc tgaagttgtc gttaagcgtg taccggaaac catgccgccg caattatttg
    26161 aaaaagcagg cggtaaaacg caaactgcac cggttgcaac cccgcaagaa ctggccgatt
    26221 acgacgccat tatttttggt acacctaccc gctttggcaa catgtccggt caaatgcgta
    26281 ccttcctcga ccagacgggc ggcctgtggg cttccggcgc actatacgga aaactggcga
    26341 gcgtctttag ttccaccggt actggcggcg gtcaggaaca aaccatcaca tccacctgga
    26401 cgacccttgc gcatcacggc atggtaattg tccctattgg ctacgcagcg caggaattat
    26461 ttgacgtttc acaggttcgc ggcggtacgc cgtacggcgc aaccaccatc gcaggcggtg
    26521 acggttcacg ccagcccagc caggaagaac tgtctattgc tcgttatcaa ggggaatatg
    26581 tcgcaggtct ggcagttaaa cttaacggct aatcttcaac aggaggatac gcatgccaac
    26641 tcaagaagcg aaagctcatc acgtcggtga atgggcatct ctgcgcaata cgtcgccgga
    26701 aatagccgag gccattttcg aagtcgccgg gtacgacgaa aaaatggcgg aaaagatttg
    26761 ggaagaaggt agtgatgaag tgttagtcaa agcctttgct aagaccgata aagattcgct
    26821 tttttggggc gaacagacca tcgaacgtaa aaacgtttaa ccagcgactc ccccgcttct
    26881 cgcgggggag ttttctgtta tttcaccgct tcattcaaca cgctatcaaa cttatccatc
    26941 gggcagaaac catcagcgtc tatcgggcaa ccgcttaatt ccagcgtcac acgctgcgca
    27001 ggtgcctgca gggttaacgc atcggcatta cgtaactgtt ccgcactctg atacacatat
    27061 tcaattttca tcaaatcgcg attggctttg ctgtcatgcc aacgctggaa aacgattttg
    27121 ccgccaatcg gcgtgcgttc gttctggtca tgcaactgat acggtttgaa atccagcgcc
    27181 gttaacagag aggcaatgtt ggagtcgtgc ccaaccaaca ctgtaatttt cggtgcgctg
    27241 gtgcgatcgg tgaccagagc tttgtcgata taactgacca gcggtttcgc aacattgcgc
    27301 gccacttccg gtgaggtaaa caggctgtcc tggtagccgt ttttaagctt cgacaacacc
    27361 ttccactgct ggtcagattt gatttctccc caggccacct gatccatcgg aaaaccttcg
    27421 taatattgca aagtaaacgc atctaccagc gagttgccga ctttcagcgg cccggaaaca
    27481 cctggttctt gttgatactt ggcgctaaag gtatttttgc catccaccag cgaacactgt
    27541 tgtttctctt tacaggcagg ggaatcttta tagttaacga ttttttccag tagctggtag
    27601 ctgtcggtaa gctggagttt gctgagctct ttctccattg ccgccaccgc ctgttcactg
    27661 aatgcggcgg aatcatcggt gatcaccggg ttaaaggttg ggtccatagt gcccattttt
    27721 tcctggtgat gcacaggaat atcacacccc gggaatgcgc cggtaataaa gaactgtgcg
    27781 gtcgcaacgg tacgttgcag actattggca taggcataaa cggtgtacgg cggcgggcat
    27841 tcccccgatt tcaccatccc ctgctctgcc agccattcac gcatgtaatg gcccatatac
    27901 acttcgagca cgccaccttt ggtggtgagt tgcccaccgg ggacgtccca ttctggccat
    27961 ttattcggcg tcgactgctc cagcacactg ccattgttcg ccagcggcgc acgtaagtta
    28021 tggcggctca tcatgagcac ttgctgtagc tgatagcctt ccggtacggt ttgtgcctga
    28081 gcgtttgaag cgagtaaaac tatccctgcc acagctgcgg cgattagcgt tttgttcatt
    28141 cctggcacct cttttgttat caatcactaa agagtgtgac agaaatatga cttttttccg
    28201 ggaacaggtt cgcaaaatgg cttgttgaac gcctgttttt ctatatacat cttcaaaaac
    28261 aggcaaggtt tgacgcaaac tatgcctgat tagcccctgc ctcgcgtacg ccgctgataa
    28321 ttgcacctgt ggctaaacag aatatctgcg gcgttaccaa tacagagaca atatttacca
    28381 ataaaaaagt gtgagactaa taacaatggt ttttagcata tgcctttgcc attaaattgc
    28441 ataacgattt aaatagtcga gttgcgcatt catttcctta ttgtttaact tgtaagcctg
    28501 agcaaaaagt tcaggaggga ggtaaacgtc ataatgattg ccagtgttca ttaaataacc
    28561 atactcaaga tcttcatctg ttgaaaagga ttcattcccc aaggagattg atgccacatt
    28621 actattaaca ataaataatg agcaaatgct atctgaaaga acagcaagaa aattcttcac
    28681 cgctttaatc ctatccgacg tgtcggtatc taaagcaagc aagttcttgt tatcattaaa
    28741 tataaactcg ggtaaatgca ggatacattt ttcgttattc aagcaactat caatgaattg
    28801 ttttttaaaa aacagaaagc tccatgacat aagactactc tgcccctgaa tttggttgtc
    28861 agattgtaga tcaacgccaa ataacgtctt tacatcttcc ctgagattat agaatgccgt
    28921 atcaacaaga gcctcgatcg tttttttatc aaccatttta atgaattcgt tgtaaacttc
    28981 cttttgcatc ttataactga ccagcgccca tgaataatca tgttgtttta aaaccagtat
    29041 agctcttaac agacaatatc catcgccatc tacaggagca tattttaatc ctaatgcctg
    29101 gttagtttca cgctgaataa aagatatacc agacaaatca atgtcagaat ccaaatcaga
    29161 tattcccggc gtatttatcc gctctggctg gacacttata ttttcatcat caaaacaata
    29221 ctcagaaaaa acatcatcac acgcattaat gttttcaata tactccataa agttatacca
    29281 ataataacct ttaaaatctg tgatagactc tgaagctctg cccggcaagg acactctaac
    29341 aatatcaata tctcgaacat attgtatagt atatgtaata cctcctgaaa cccctgaata
    29401 aatttgtgta tcattagtac gcaatgttct cataaataat gatagatcat tatcattctg
    29461 catttcctca aattcttttt ctagtgattc acattccaga catggagtat cctcttcatt
    29521 tactttacgt ctgagttcat tgtataaccg cataaaacac accagtgtgt tttcaaaaag
    29581 cgtgattgaa tatgtttgat ttttttcgta ctcatttttt atatcgttcc aggcctgttt
    29641 caaataatta tttgcagtgc a
//
LOCUS       DAPHKZ010000051        28353 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.051, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000051 DAPHKZ010000000
VERSION     DAPHKZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28353
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.051"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..290)
                     /gene="tuf"
                     /locus_tag="RH288_002348"
     CDS             complement(<1..290)
                     /gene="tuf"
                     /locus_tag="RH288_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDV4031395.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAA"
     gene            complement(361..2475)
                     /gene="fusA"
                     /locus_tag="RH288_002349"
     CDS             complement(361..2475)
                     /gene="fusA"
                     /locus_tag="RH288_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDV4031396.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
                     RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEW
                     HQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPL
                     AGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDEAPSNVAQAVIEARGK"
     gene            complement(2572..3042)
                     /gene="rpsG"
                     /locus_tag="RH288_002350"
     CDS             complement(2572..3042)
                     /gene="rpsG"
                     /locus_tag="RH288_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDV4031397.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3139..3513)
                     /gene="rpsL"
                     /locus_tag="RH288_002351"
     CDS             complement(3139..3513)
                     /gene="rpsL"
                     /locus_tag="RH288_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDV4031398.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3639..3926)
                     /gene="tusB"
                     /locus_tag="RH288_002352"
     CDS             complement(3639..3926)
                     /gene="tusB"
                     /locus_tag="RH288_002352"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HDV4031399.1"
                     /translation="MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYL
                     ESLRNAPIKVYALNEDLIARGLTGQISNDIILIDYTDFVRLTVKHPSQMAW"
     gene            complement(3934..4293)
                     /gene="tusC"
                     /locus_tag="RH288_002353"
     CDS             complement(3934..4293)
                     /gene="tusC"
                     /locus_tag="RH288_002353"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HDV4031400.1"
                     /translation="MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGV
                     FQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLE
                     ADALRRELANYDVILRF"
     gene            complement(4293..4679)
                     /gene="tusD"
                     /locus_tag="RH288_002354"
     CDS             complement(4293..4679)
                     /gene="tusD"
                     /locus_tag="RH288_002354"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HDV4031401.1"
                     /translation="MRFAIVVTGPAYGTQQASSAFQFAQALIADGHELSSVFFYREGV
                     YNANQLTSPASDEFDLVRAWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSN
                     LQQGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4679..5401)
                     /locus_tag="RH288_002355"
     CDS             complement(4679..5401)
                     /locus_tag="RH288_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV4031402.1"
                     /translation="MSRSLLTNETSELDLLDQRPFDQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSSVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5568..6380)
                     /gene="fkpA"
                     /locus_tag="RH288_002356"
     CDS             complement(5568..6380)
                     /gene="fkpA"
                     /locus_tag="RH288_002356"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDV4031403.1"
                     /translation="MKSLFKVTLLATTMAVALHAPITFAAEAAKPATAADSKAAFKND
                     DQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLV
                     IPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK"
     gene            6601..6819
                     /locus_tag="RH288_002357"
     CDS             6601..6819
                     /locus_tag="RH288_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HDV4031404.1"
                     /translation="MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(6868..7458)
                     /gene="slyD"
                     /locus_tag="RH288_002358"
     CDS             complement(6868..7458)
                     /gene="slyD"
                     /locus_tag="RH288_002358"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDV4031405.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH"
     gene            complement(7553..7753)
                     /locus_tag="RH288_002359"
     CDS             complement(7553..7753)
                     /locus_tag="RH288_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HDV4031406.1"
                     /translation="MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMRE
                     ADKEARDHVRKDEQVIGIFHPD"
     gene            complement(7763..9568)
                     /gene="kefB"
                     /locus_tag="RH288_002360"
     CDS             complement(7763..9568)
                     /gene="kefB"
                     /locus_tag="RH288_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
                     /protein_id="HDV4031407.1"
                     /translation="MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGP
                     WGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALL
                     AGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV
                     IPALALVPLLAGSADEHFDWMKVGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFT
                     AATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFI
                     SVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGG
                     EFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTLLLMKLVDKWLSRQFNGPEEEDE
                     KPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGD
                     ATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELL
                     QAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADT
                     VQISRAREARRELEEIFQREMQQERRQLDGWDEFE"
     gene            complement(9568..10119)
                     /gene="kefG"
                     /locus_tag="RH288_002361"
     CDS             complement(9568..10119)
                     /gene="kefG"
                     /locus_tag="RH288_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312229.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HDV4031408.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHY
                     PDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
                     QELASHARAYGDWLANPLSPGGR"
     gene            10250..12163
                     /locus_tag="RH288_002362"
     CDS             10250..12163
                     /locus_tag="RH288_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4031409.1"
                     /translation="MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAALEYVIDGDREYRQLEAQLHDAN
                     ERNDGHAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIH
                     IEQQSMFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADE
                     SPIQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVEPF
                     DGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIAR
                     LEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQ
                     EQLEQMLLEGQSN"
     gene            12163..13185
                     /locus_tag="RH288_002363"
     CDS             12163..13185
                     /locus_tag="RH288_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDV4031410.1"
                     /translation="MAQITTTDANEFSSSAEFIPMRGFSNCHLQTMLPRLFRRQVKFT
                     PYWQRLELPDGDFVDLAWSENPAQAQHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGW
                     LGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
                     CLLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAY
                     PGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIH
                     AKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTY
                     LEAKSC"
     gene            13179..13397
                     /locus_tag="RH288_002364"
     CDS             13179..13397
                     /locus_tag="RH288_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HDV4031411.1"
                     /translation="MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKR
                     QLQCGEAVLVWSELHETVNIMPRSQFRE"
     gene            13451..14320
                     /locus_tag="RH288_002365"
     CDS             13451..14320
                     /locus_tag="RH288_002365"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HDV4031412.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYD
                     EAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(14375..14779)
                     /locus_tag="RH288_002366"
     CDS             complement(14375..14779)
                     /locus_tag="RH288_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDV4031413.1"
                     /translation="MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVVAA"
     gene            15081..15713
                     /gene="crp"
                     /locus_tag="RH288_002367"
     CDS             15081..15713
                     /gene="crp"
                     /locus_tag="RH288_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HDV4031414.1"
                     /translation="MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            15765..17855
                     /locus_tag="RH288_002368"
     CDS             15765..17855
                     /locus_tag="RH288_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312236.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDV4031415.1"
                     /translation="MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVP
                     ACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLLLAKDVPLPFLLTGLTLVLGVTA
                     ELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
                     LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLS
                     AQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARL
                     RVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPL
                     YARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWI
                     LMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASY
                     LILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQW
                     QSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEP
                     AFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQ
                     RLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPH
                     HGIWLSRKLRDSKA"
     gene            complement(17922..19142)
                     /gene="argD/dapC"
                     /locus_tag="RH288_002369"
     CDS             complement(17922..19142)
                     /gene="argD/dapC"
                     /locus_tag="RH288_002369"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     acetylornithine/succinyldiaminopimelate transaminase"
                     /protein_id="HDV4031416.1"
                     /translation="MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEY
                     VDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERV
                     VFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQ
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAF
                     HPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSD
                     IRGMGLLIGAELKPQYKGRARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEG
                     MQRFAHAVAKVVGA"
     gene            complement(19228..19791)
                     /gene="pabA"
                     /locus_tag="RH288_002370"
     CDS             complement(19228..19791)
                     /gene="pabA"
                     /locus_tag="RH288_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HDV4031417.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKP
                     QKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHG
                     KTSPITHNGEGVFRGLANPLTVTRYHSLVVEPDSLPACFDVTAWSETREIMGIRHRQW
                     DLEGVQFHPESILSEQGHQLLANFLHR"
     gene            complement(19823..20425)
                     /locus_tag="RH288_002371"
     CDS             complement(19823..20425)
                     /locus_tag="RH288_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HDV4031418.1"
                     /translation="MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRA
                     ATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNAL
                     MQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
                     SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE"
     gene            complement(20415..20582)
                     /locus_tag="RH288_002372"
     CDS             complement(20415..20582)
                     /locus_tag="RH288_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HDV4031419.1"
                     /translation="MKKLTDKQKSRLWELQRNRNFQASRRLEGVEMPLVTLTAAEALA
                     RLEELRSHYER"
     gene            complement(20687..21259)
                     /gene="ppiA"
                     /locus_tag="RH288_002373"
                     /gene_synonym="rotA"
     CDS             complement(20687..21259)
                     /gene="ppiA"
                     /locus_tag="RH288_002373"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HDV4031420.1"
                     /translation="MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELEL
                     DKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPSKPVVILSAKVLP"
     gene            21530..22711
                     /gene="tsgA"
                     /locus_tag="RH288_002374"
     CDS             21530..22711
                     /gene="tsgA"
                     /locus_tag="RH288_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HDV4031421.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAA
                     MFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
                     EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTV
                     LAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVL
                     TCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTS
                     H"
     gene            22973..25516
                     /gene="nirB"
                     /locus_tag="RH288_002375"
     CDS             22973..25516
                     /gene="nirB"
                     /locus_tag="RH288_002375"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HDV4031422.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFY
                     DKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
                     AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGV
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDI
                     YAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQKDGTYS
                     VIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCT
                     RECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADIDRETLIKYLDRFMMFY
                     IRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVLCEWTETV
                     NTPSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA"
     gene            25513..25839
                     /gene="nirD"
                     /locus_tag="RH288_002376"
     CDS             25513..25839
                     /gene="nirD"
                     /locus_tag="RH288_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HDV4031423.1"
                     /translation="MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISN
                     IDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYEARVKDG
                     VVQLRG"
     gene            25965..26771
                     /gene="nirC"
                     /locus_tag="RH288_002377"
     CDS             25965..26771
                     /gene="nirC"
                     /locus_tag="RH288_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HDV4031424.1"
                     /translation="MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKAGSISHGQMW
                     AILPQTWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALC
                     NWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYT
                     LAGIGHNLLWVTLGNTLSGAVFMGLGYWYATPKANRPVADKFNQTETAAG"
     gene            26790..28163
                     /gene="cobA"
                     /locus_tag="RH288_002378"
     CDS             26790..28163
                     /gene="cobA"
                     /locus_tag="RH288_002378"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDV4031425.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALA
                     FIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
                     LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQ
                     KLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
                     LNWFSNH"
BASE COUNT         6849 a         7609 c         7168 g         6727 t
ORIGIN      
        1 gcagcaccgg tgatcatgtt tttaacatag tcggcgtgcc ccgggcagtc tacgtgtgcg
       61 tagtgacggg tcggggtgtc gtattcaacg tgagaagtgt tgatggtgat accacgagct
      121 ttttcttccg gcgcgttatc gatctggtcg aatgcacgag cagcaccgcc gtaggtttta
      181 gccagtacgg tggtgattgc agcggtcaga gtagttttac cgtggtcaac gtggccgata
      241 gtaccaacgt taacgtgcgg ttttgtacgt tcaaattttt ctttagacac ggctatattc
      301 cttactatag tgctctcccc ttcaggagag agcacgggac tttggtatta acccttaggc
      361 ttatttacca cgggcttcaa ttacggcctg agcaacgtta ctcggcgctt catcatactt
      421 caggaattcc atagtgtatg atgcacgacc tttggtcaga gaacgcagct gagttgcgta
      481 tccgaacatt tcagacagcg gtacttcagc gtggatctta acgccagtaa cttcagattc
      541 ctgacctttg agcataccac gacgacggct caagtcaccg ataacgtcac cggtgttctc
      601 ttccggagtt tctacttcaa ccttcatgat cggctcaagc agaactggtt tcgctttctt
      661 aaagccttct ttaaaggcga tagaagcagc cagtttaaac gccagttcag aggagtcaac
      721 gtcatggtaa gaaccgaagt gcagacgaat acccatgtct actaccgggt agcctgccag
      781 cggacctgct ttcagctgtt cctggatacc tttatcaacg gccgggatgt attcgccagg
      841 gattacacca cctttaatgt cgttgatgaa ctcgtagcct ttcgggtttg aacccggctc
      901 cagcgggtac atgtcgataa caacatgacc atactgacca cgaccaccag actgtttcgc
      961 gtgtttacct tcaacatcgg taactttctg gcggatagtt tcacggtaag caacctgcgg
     1021 tttacctacg ttcgcttcaa cgttgaattc acgcttcata cggtcaacga tgatgtcgag
     1081 gtgcagttcg cccatacccg cgatgatggt ctggttagat tcttcgtcag tccatacacg
     1141 gaaagacggg tcttctttag ccagacggcc cagagccaga cccatttttt cctggtcagc
     1201 tttggttttc ggttcaactg cgatggagat taccggctca gggaattcca tacgttccag
     1261 aatgatcggc gcatccgggt cacacagggt gtcaccagtg gttacgtctt tcagaccgat
     1321 agcagcagcg atgtcgcccg cgcgaacttc tttgatctct tcacgtttgt tagcgtgcat
     1381 ctgaacgata cgaccgaaac gctcacgtgc agctttcacg gagttcagta cggtatcacc
     1441 agagttaacc acaccggagt aaacacggaa gaaggtcagg ttaccaacaa acgggtcggt
     1501 agcgattttg aacgccagtg cagagaacgg ctcgtcatca cttgcgtgac gttcagccgg
     1561 agtgtcttta ccgtcgtcca ggataccgtt gatcgcaggt acgtcaaccg gggatggcag
     1621 gtaatcaatt accgcatcca gcatcgcctg aacacctttg ttcttgaacg cagaaccaca
     1681 ggttaccagg atgatttcgt tgttcagaac gcgctgacgc agagcacctt tgatttctgc
     1741 ttcagtcagt tcttcaccac ccaggtattt ttccatcagc tcttcagaag cttcagctgc
     1801 ggattcgatc aggttctggt gccattcgtt agccagttca accatgtctg ccgggatatc
     1861 ttcgtattcg aaggttacgc cctggtcagc gtcgttccag ttgatagctt tcattttcac
     1921 caggtcaaca acaccggtga aatgttcttc agcaccaatc gccagctgca gcggaaccgg
     1981 gttcgcgccc agacgggttt tgatctggtt aacaactttc aggaagttcg cacccatgcg
     2041 gtccattttg ttaacgaacg caatgcgcgg aactttatat ttgtttgcct gacgccatac
     2101 ggtttcagac tgcggctgaa caccaccaac tgcgcagtaa accattaccg caccatcgag
     2161 aacacgcatg gaacgttcta cttcgattgt gaagtcaacg tgccccgggg tgtcgatgat
     2221 gttgatgcga tgcggctcat actgcttagc cataccagac cagaatgcag tagtcgcagc
     2281 ggaagtgatg gtaataccac gttcctgctc ctgctccatc cagtccatgg ttgcagcgcc
     2341 gtcatgaact tcaccgattt tatggtttac accggtgtag aacagaatac gttcggtagt
     2401 agtggtttta ccggcgtcga tgtgcgcact gataccgatg ttacggtagc gtgcgatggg
     2461 tgttgtacga gccatttgtt tcctcgttta tcttttaggc gttcaattta agtagcccaa
     2521 agcgggctgc ttactggaag cgcccgcctg gtgactaaaa ctccgaaggg attaccaacg
     2581 gtagtgtgcg aacgccttgt tggcttcggc catacggtga acgtcttcac gtttcttaac
     2641 tgcagtacct ttgttttctg cagcatcaga aagttcgttc gccaggcgca gagccatgga
     2701 tttatcaccg cgtttacgag cagcttcaac gatccaacgc attgccagag cattacgacg
     2761 aaccggacgg acttcaactg gtacctgata agtagaacca ccaacgcggc gagacttaac
     2821 ttctacagtc gggcgcacgt tttcgagagc tacttcgaat gcttccagtt cagatttacc
     2881 agagcgctga gccagggtct ccagcgcgct gtatacgata gattcagcag tagatttttt
     2941 accatctacc atcaggatat ttacaaattt agccagcagt tctgatccga acttcggatc
     3001 cggcagaatt ttacgctgac caatgacgcg acgacgtggc atggaaatac tccgttgtta
     3061 attcaggatt gtccaaaact ctacgagttt agtttgacat ttaagttaaa acgtttggcc
     3121 ttacttaacg gagaaccatt aagccttagg acgcttcacg ccatacttgg aacgagcctg
     3181 cttacggtct ttaacgccgg agcagtcaag cgcaccacgt acggtgtggt aacgaacacc
     3241 cgggaggtct ttaacacgac cgccacggat caggatcacg gagtgctcct gcaggttgtg
     3301 accttcacca ccgatgtagg aagtcacttc gaaaccgtta gtcagacgaa cacggcatac
     3361 tttacgcagc gcggagttcg gttttttagg agtggtagta tatacacgag tacatacgcc
     3421 acgtttttgc gggcatgctt ccagcgcagg cacgttgctt ttcgcaactt tgcgagcacg
     3481 tggtttgcgt accagctggt taactgttgc cattaaatag ctcctggttt tagcttttgc
     3541 ttcgtaaaca cgtaataaaa cgtcctcaca caatatgagg acgccgaatt ttagggcgat
     3601 gccgaaaagg tgtcaagaaa tatacaacga tcccgccatc accaggccat ctggctgggg
     3661 tgcttaaccg taagtctgac gaaatcagta tagtcaatga gaatgatgtc gttcgaaatt
     3721 tgaccagtca aaccgcgggc aataaggtct tcgttcaggg catagacctt aatgggggca
     3781 ttacgcagac tttcaaggta gcggttaccg tcaactgcgg cagttacgcc atcttgcaat
     3841 aatagcagtt cgtctccttc actgagcaga cgcagcagcg cagcaaaatc cgtcagccag
     3901 ggtgagcgat gtaatgtgtg cagcataaac gcctcaaaac ctcaaaataa catcgtagtt
     3961 ggcgagttcg cggcgtaagg catctgcttc gagcggcgtg gcttcgacaa caaagggtgt
     4021 ctgcggatct aacccgcgtt cgcgcagtga agccgcacaa acccagcact gttcaatgtc
     4081 gtacagaccc aacaatttaa aagtggcaat gtaatcacgc gccagcactg catcgggctt
     4141 ttgtcctggc agcagctgaa aaacgccatc agctataaag aagacagcca gatcgtcagt
     4201 taatgcggaa gttgccagta aagcatctaa accttcccgg cctgcggctg taccatgagg
     4261 tgcagtagaa aaaacaaacg caattcgttt catcagaact gtaccaccct gtcacaggtc
     4321 agcgaggctt ccgccagcgc cccaagtccg cttaaggtaa atccctgctg aaggtttgac
     4381 gaagccagcc ccagtcttcc ggcctccgtt tcatcaacaa cgccacggcg taatgctgcc
     4441 gctacgcaga tattcagcgc cacaccatgt tgcgcattca gttgttgcca ggcccgtacg
     4501 aggtcaaatt cgtcacttgc cggagaggtc aattggttag cgttatagac cccttcccga
     4561 tagaaaaaga cgctgcttaa ctcatggcca tctgctatca gcgcctgcgc aaactgaaaa
     4621 gcactactcg cctgttgcgt accgtatgct ggcccggtca ccacgatggc aaaacgcatt
     4681 acttatcttg cccctggaaa tcaccgctct tgaactggcg gatgtagaga tagacagtgt
     4741 gtttggagat gttcaggcgg tcagcaacct ggttgatcgc atctttaata tcgaagatcc
     4801 ctttctcgta gagattcagc acgatctgac gatttttggc gttattagaa acattgcgat
     4861 cggcattcac ttcttcgatg gtgaactcca gcgtttgggt aaccagatct tcaacagaag
     4921 aggcaaagtt gacgcttgaa ccgacatccg gggtttctgg cggcacaaag gtgctcataa
     4981 tctgcgagaa gggaacatca agattcatat tgatgcacag cagaccaatt acacgctgtt
     5041 cgcggttacg aatcgcgata gtcagggact tcattaatac gccgcttttg gcgcgagtaa
     5101 agtagcattt agaaacgctg ctatccgctc ccgtcatatc gtgcagcata cgtagcgcca
     5161 ggtcagtaat tggcgaacca atcttccggc ctgtatgttc accgttagca atgcgaatgg
     5221 ctgaacattt tagatcctgc aaagagtgca aaacgatttc acagtgggag ccaataagca
     5281 tcgctaaccc gtccaccacc gcttcgtagg atttcagaat atcaaaatcg gtctggtcga
     5341 aaggacgttg atccagtaaa tccaactcac tggtttcgtt ggttaaaagc gacctggaca
     5401 tgaaaaaaaa cactcctttt caggagcctg tcgttaactt ttcagggcag gctcattaat
     5461 gatgcgggta actaaattaa tacagcggag gttccgcttt ccagcactaa ttatatccgg
     5521 cctgtaataa aaaaaccgcc gcctggtcag gcggcggttc ttaatgctta ttttttagca
     5581 gaatctgcgg ctttcgcatc agcttccggc tttgcatcag ccttcggcgc tggtttcaca
     5641 tccagcagct ctacgtcaaa caccagggta gaattcggtg ggatccccgg aacacccgct
     5701 ttgccgtaag ccagttctgg tggaataacc agtttgatct taccgccttt cttgatgttc
     5761 ttcagacctt ctgtccaacc cgggataaca ccgtccagac ggaaagaaag cggttcacca
     5821 cgggtgtaag agttgtcgaa ctctttaccg tcgatcagcg tacctttgta gttcactaca
     5881 acagtatcgc tgtctttcgg tgcttcgcct ttaccggctt ctactacctg ataaaccaga
     5941 ccagttgaag aggttttcac acctttctct ttggcaaatt tctcgcggta ctctttacct
     6001 tttgcttcgt tatcagccgc gtctttttcc atcttcgcct gagcagaaga cttcacgcga
     6061 gcttcgaatg cttgtagagt ctgttcgatc tcttggtcgg agagtttgct cttatcagca
     6121 aatgcatcct gaacaccagc gatcagctga tctttatcca gtttgatgcc cagtttttct
     6181 tgttctttta gagagttttc catgtaacga cccagcgagg cacccagtgc ataagctgat
     6241 ttctgatcgt catttttgaa cgctgctttg ctgtcagcag ctgtagcagg ttttgcagct
     6301 tcagcagcaa aagtgattgg tgcatgcagg gcaacggcca ttgtggtcgc cagcagcgtt
     6361 actttaaaca gtgatttcat ccatatctcc aggatcgggg catctcaccc cagggttaac
     6421 tattatcaga agggtactat aaagcgttgt cgaacaaatc tacatacaga cacgccctat
     6481 tatcatctat tttcagactc tttttgttta aattagtttc gatgaccgcg aaatgagtgc
     6541 tgtctcgggc agcaaagtta agtagaatcc gcggcgacca ttcgacaaaa gaggtgaatc
     6601 atgcaggatt tatcattgga agcacgcctg gcagagctgg agagccgact ggcttttcag
     6661 gaaatcacca ttgaagaact gaacgtcacg gtgaccgctc atgaaatgga gatggcgaaa
     6721 ctgcgcgatc atctgcgtct gctgaccgag aagttaaaag ccagccagcc gtcgaacatc
     6781 gcgtcgcagg ctgaagaaac gccaccgcca cattattgag gcgtaaaaaa agcggggatt
     6841 ccccgctttt ttgtcacttt ttcggtatta gtggcaaccg caaccgccgt tgcctttacc
     6901 gccacagcag ccttcgccac cgtgttcatg accgtgatcg tggccatgac cgccgcagca
     6961 accgtcgtgg tcgtgatcgt ggtggtgatc gtgcgcgccg tgaacgtgac catgagccag
     7021 ttcttcttca gtcgcttcgc gaatcgccac aacttcaacg ttgaatttca ggttctgacc
     7081 ggccagcatg tggttaccat caaccacgac gtgatcgtct tcaaccgcag tgatttcaac
     7141 cggtaccgga ccctggtcgg tttcagccag gaaacgcata cctacctgca gttcatcaac
     7201 gcccataaat acgtctttag gaacacgttg caccaggttt tcgtcgtact gaccgtaagc
     7261 gtcgttcgcg ccaacagcga catcaaattt gtcgccaact tcatgacctt ccagcgccgt
     7321 ttccaggcca gagatcaggg aaccgtgacc atgcaggtag tccagcggcg cactcaccgg
     7381 agactcatca accaacacac cgtcttctgt acgtacctga taggccaggc tgaccaccag
     7441 gtcttttgct actttcatga tatctcctga gcatgggaag aatagtggcg cagattgtag
     7501 cggaattctg cagccgtgta ctcactagct taaaaaaact cggcgcatat cgctagtccg
     7561 gatgaaaaat cccgatcact tgctcatctt tgcgaacgtg atcgcgggct tctttgtctg
     7621 cttctcgcat ctgatgtccg cacttaacac attcaacaat atcaatatta ttttcgcgcc
     7681 acatcgccat tgaatcctgc gcctgacagg ccgggcattt tgcgcccgca ataaaacgtt
     7741 ttcggattgc catctttacc ctctactcaa attcatccca gccgtccagc tggcgtcgtt
     7801 cttgttgcat ttcacgctgg aaaatctctt ccagttcgcg tcgggcttcc ctggcgcgag
     7861 aaatttgtac ggtatcggca tgcattggga tgagctctcg cagcatccgc atatccaggc
     7921 ggcgaaaatg cagttgcgct cgctgtgcct gatgcggatg catgccaagc gtgaccagcg
     7981 tcttgcgccc cagctctaac gcactggaga atgtttcacg ggaaaactgc gtcacccctg
     8041 cctgtaataa ctcatgcgct tccacacgtc cgcgcgctcg cgcaagaata tgcaaatgcg
     8101 gaaagtgctg ttggcatatt tccaccagct tcatggtgtc ttccggctcg ttacaggtaa
     8161 tgacgataga ctcagcggcc tctgcacccg cagaacgtaa aagatcgacc tgcgtggcgt
     8221 cgccgtaata aactttgtag ccgtatttac gcatcaggtt aacggcgctg atatcccgct
     8281 ccagcacggt aatgcgcatt ttatttgcca tcagcaaacg accaatcacc tgaccaaaac
     8341 gcccgaagcc cacgacaatg acctggggtt tatcatcgtt gacccacggt ttttcgtctt
     8401 cttcttccgg tccgttaaac tggcgggata gccatttatc caccagcttc atcagcaaca
     8461 gcgtggtcat catggaaagc gtcaccgtca ccagcaacaa cgccatctgg tcgccctgga
     8521 ataagcgttg tgaagaagcg gtagaaaaga ggacaaaggc aaactcacca ccctgactca
     8581 acacgccagc aaactgcatc cgctctgagc tacgcacgcc atacaatcgc gccagcagat
     8641 acagcacgag aattttcacc gccaccagca caaccacgct tatcactacc cacaacagat
     8701 gggtataaag caccccgagg ttgagtgaca tgccgacaga gataaagaac aaaccgagca
     8761 gcaagccttt gaagggatcg atagccgttt ccagttcatg gcgatattca ctttccgcca
     8821 gcagcacgcc cgcaataaat gtaccgagcg ccatcgacag ccccagcgca tccataaaca
     8881 atgcggaacc caacaccagc agcagcgtcg cggcggtgaa cacttcccgc acgccagaag
     8941 ctgcaataaa gcggaatacc ggacgcagta aatagcgccc accaatcagc atgccgacaa
     9001 acgccagcac cttcatgccg accttcatcc agtcgaaatg ttcgtctgcc gaccccgcca
     9061 acaacggcac taacgccagt gctgggatta ctgccagatc ctgaaacagc agaaccgaaa
     9121 acccgagctg gccggattcg ctgcgattca tccctttctc acgcatcaat tgcaacgcca
     9181 ttgcagttga agacatcgca aggccaatgc caccgaccac cgccgcctgc caggcgaaat
     9241 ccgtcagcat caataatccc gccagcaacg ccgcgcttaa cagcacctgt gccgcgccta
     9301 cgccaaaaat cgaacgccgc agttgccaaa gtttggaggg attcaactca aggccgatga
     9361 taaacatcag gaataccacg ccgagttccg aaaagtggag gatctcatcg acgtcgctaa
     9421 taaaccccag cccccacggg ccaattgcaa tccctgccag caaatatccc aacacagcgc
     9481 caatacccag ccgcgatgcc agcggcaccg cagccaccgc cgcgaagaga aacagcactc
     9541 ctgcgagtaa aaaatcggaa ccttccatca gcggcctcct ggagacagcg gatttgccag
     9601 ccagtcaccg taggctctgg cgtggctcgc cagctcctgt gcgctttgcc gtctcgccca
     9661 gtaaataatg atgggactta accaatgcat ccggcacatg cccgccgcca gttcaaaggg
     9721 gcgcagcaca tcgctcatcg ggtagcgatt cagcgcgtca taacggtaag cactttccgg
     9781 ctcgccggtg gtaatcacgc tacgccagta ctttcccgcc agttggtttc ctcccggccc
     9841 gctggcaaaa ccacgactta atacccggtc cagccactct ttcagtagcg ccgggcagct
     9901 ataggtataa agaggatgct gaaagacaat cacctcgtgc tcgcgcagta atgcctgctc
     9961 acgggggata tcaataaaaa aatcgggata gtgcgcgtaa aggtcgtgca cggtaacatt
    10021 gctgagctgc gtggccggtt taagcagtac ccggtttgcc accgagtcct gagattccgg
    10081 atgggcatac agcagcaaaa ctttcgctgg ctgagacatc atccccctcc cggtatggtt
    10141 tttgtgtata gtcgctgttt tgggctacca ttgcgcccgg tgcggcagct cgcccataca
    10201 ttacattatc ataatgataa gttaacatag tctgaacata cggcacctta tgattgtttt
    10261 ctcctcgtta caaattcgtc gcggcgtgcg cgtcctgctg gataatgcca ccgccaccat
    10321 caaccctggg cagaaagtcg gcctggtggg taaaaacggc tgtggtaaat ctaccctgct
    10381 ggcattgctg aaaaatgaaa tcagcgccga cggcggcagc tacacctttc cgggaagctg
    10441 gcaactggcg tgggtgaatc aggaaacgcc ggcgttaccg caagcggcgc tggaatatgt
    10501 cattgacggc gaccgtgaat atcgtcaact agaagcgcag ctacacgacg ccaacgaacg
    10561 taacgacggg cacgccattg cgaccattca tggcaagctg gatgctattg acgcatggag
    10621 tattcgctcc cgtgctgcca gcctgctgca cggcctcggt ttcagcaatg aacaactgga
    10681 gcgcccggta agtgattttt ccgggggctg gcgtatgcgt cttaaccttg cccaggcgct
    10741 gatttgccgt tcagacttgc tgctgctcga cgaaccgact aaccacctcg atctcgatgc
    10801 cgttatctgg ctggaaaaat ggctgaagag ctatcagggc acgctgatcc tgatctctca
    10861 cgaccgcgac ttcctcgatc cgatcgtcga taaaattatt catatcgaac aacaaagcat
    10921 gttcgagtac accggcaact acagttcgtt tgaagtacag cgcgccaccc gtctggcgca
    10981 gcaacaagcg atgtacgaaa gccagcagga acgcgtagcg catctgcaaa gttatatcga
    11041 ccgtttccgt gccaaagcca ccaaagcgaa gcaggcccag agccgcatta agatgctcga
    11101 gcgtatggag ctaattgccc ccgcgcacgt cgacaacccg ttccgcttta gcttccgcgc
    11161 gccggaaagc ctgccaaatc cgttactgaa gatggaaaaa gtcagcgcgg gctatggcga
    11221 tcgcattatt ctcgactcga ttaaactgaa cctggtgccc ggctcgcgta ttggtctgtt
    11281 aggccgcaat ggcgcgggta aatcgacatt aatcaaactg ttagccggtg aacttgcgcc
    11341 agtcagcggt gaaattggtc tggcgaaagg gatcaaactc ggctacttcg cccagcatca
    11401 acttgaatac ctgcgcgccg acgaatcacc tattcaacat ctggcacgtt tagcgccgca
    11461 ggagctggaa caaaaactgc gtgactacct cggcggcttt ggtttccagg gcgataaagt
    11521 aaccgaagaa acgcgccgct tctccggtgg ggaaaaagcc cgcctggtgc tggcattaat
    11581 tgtctggcag cggccgaatc tgctgctgct cgacgaaccg actaaccacc ttgacctcga
    11641 catgcgtcag gcactcaccg aagcattaat cgagtttgaa ggcgcgctgg ttgtcgtttc
    11701 gcacgaccgt catttgctgc gttccaccac tgacgatctc tacctggttc acgatcgtaa
    11761 agtcgaaccg ttcgacggcg atctggaaga ttatcaacag tggttgagcg acgtacaaaa
    11821 gcaggaaaac cagaccgacg aagcgccaaa agagaatgcg aacagcgccc aggcacgtaa
    11881 agatcagaag cgtcgggaag ctgagctgcg tgcgcaaacc cagccactgc gtaaagagat
    11941 tgcccgtctg gaaaaagaga tggagaagct gaacgcgcaa ctggcgcagg cggaagagaa
    12001 actcggcgac agcgaactgt atgaccagag ccgtaaagcg gagttgaccg cctgcctgca
    12061 acagcaagcc agcgccaaat ccggcctgga agagtgcgaa atggcatggc tggaagccca
    12121 ggagcagctt gagcagatgc tgctggaagg ccaaagcaac tgatggcgca gataacgacg
    12181 accgatgcca atgaattcag cagcagtgct gaattcatcc ccatgcgcgg ctttagcaat
    12241 tgtcatctgc aaaccatgct gccgcgtctg tttcgtcgtc aggtgaaatt caccccgtac
    12301 tggcagcggc tggagttgcc cgacggcgat tttgtcgatc ttgcgtggag tgaaaaccct
    12361 gcacaggcgc aacataaacc tcgtctggtg gtgtttcacg ggctggaagg cagtctcaac
    12421 agcccttacg cccacggtct ggttgaggcg gcgcaaaagc gcggctggct gggcgtggtg
    12481 atgcattttc gcggatgcag cggtgaacca aaccgtatgc accgcattta ccattcgggc
    12541 gaaaccgaag acgccagttg gtttttacgc tggctgcaac gcgaatttgg tcatgcgcca
    12601 acggctgccg tcggctattc gctcggcggt aatatgctgg cctgtttgct ggcaaaggaa
    12661 ggcaatgatc tcccggttga tgcggcggtg attgtctctg cgccgtttat gctggaagcc
    12721 tgtagctatc atatggaaaa gggcttttcc cgcgtttatc agcgttactt gctgaacctg
    12781 ttaaaagcca atgccgcgcg caagctggca gcctaccccg gaacgctgcc gattaatctc
    12841 gcgcagttaa aatcggtacg tcgcatccgt gaatttgacg atctcatcac cgccagaatt
    12901 cacggctacg ccgacgctat cgactattat cgtcagtgta gcgccatgcc gatgctgaac
    12961 cggatcgcca aaccgacgct gattattcac gccaaagacg atccgtttat ggatcatcag
    13021 gtgatcccga aaccggaaag tctccccccg caggtggagt atcaactgac tgaacatggc
    13081 ggtcatgttg gctttattgg cggtacatta cttcatccgc aaatgtggct ggagtcacgc
    13141 attcctgact ggttaacaac gtatctggag gcgaaatcat gttgattccg tggcaagacc
    13201 tctcccccga aacgctggaa aatttaattg aaagctttgt gttacgtgaa ggcaccgatt
    13261 atggtgaaca tgagcgtaca cttgaacaga aagtcgccga cgtcaaacgc cagctacagt
    13321 gcggagaagc ggtgctggta tggtcggagc tgcacgaaac ggtcaatatt atgccgcgca
    13381 gtcagtttcg cgaataacct gcaaccgtcg gcggacgaga taataatgat agctaagtca
    13441 tggagttact atgtctgcca aacatccggt cattgcggta acaggatcca gcggcgcggg
    13501 gaccaccacc accagcctcg cgtttcgtaa aatattcgcg cagttaaatc tgcatgcagc
    13561 tgaggtggaa ggcgacagtt ttcaccgtta cacccgcccg gaaatggaca tggcgatccg
    13621 caaagcgcgc gacgccgggc ggcatatcag ctacttcggc cccgaggcta acgacttcgg
    13681 cctgctggaa caaaccttca ttgaatacgg tcagagcggc aaagggaaat ctcgcaaata
    13741 tctgcatacc tacgacgaag ccgtaccgtg gaatcaggta ccggggacat tcaccccctg
    13801 gcaaccttta ccggaaccca ctgatgtact gttttatgaa ggtttacacg gcggcgtagt
    13861 cacgccacag cataacgttg cgcagcatgt ggacttactg gtcggcgtgg tgcctatcgt
    13921 taaccttgag tggattcaaa aactgatccg cgacaccagc gagcgcgggc actcacgaga
    13981 agcagtgatg gactcagtag tgcgttcaat ggaagactat atcaactaca tcacaccgca
    14041 gttttcccgc acccatctta acttccagcg cgttcccacc gtcgacactt caaacccgtt
    14101 cgcggcaaaa ggtatcccgt cgctcgatga aagctttgtg gtgatccatt ttcgtaatct
    14161 ggaagggatc gatttcccct ggctgctggc gatgttgcaa ggctcattca tttcccacat
    14221 caatacgtta gtggtaccgg gcggcaaaat gggtctggca atggaattaa ttatgctgcc
    14281 gctggtgcaa cgattgatgg aaggaaagaa aatcgagtaa ctctgctatt acgccggata
    14341 aaatactatc cggcttcaca acgggatagt taagtcacgc ggcaaccact tcatacgagt
    14401 gagtaatatt caccgctttt tccagcatca acgccactga acaatatttc tcggcagaga
    14461 gatcaaccgc acgcgcaacc gctgcgtctt tcaggtcgcg accggtgacg ataaaatgca
    14521 gattaatgtg cgtaaacagg cgtggtgcct cttcgcggcg ttcagaggtc aattttactt
    14581 cacaatcgac cacatcctga cgcccttttt gcaggatcga aaccacatcg atggcactgc
    14641 aaccacccgc cgccatcaac accatttcca tcggacttgg tgctttatcg cctgagttgc
    14701 cgtccattaa aatctgatga ccagaggcgg attcgcccag aaaagttaac ccttcgaccc
    14761 acttcactcg cgcttgcatt tttgctactc cactgcgtca attttcctga cagagtacgc
    14821 gtactaacca aatcgcgcaa cggaaggcga cctgggtcat gctgaagcga gacaccagga
    14881 gacacaaagc gaaagctatg ctaaaacagt caggatgcta cagtaataca ttgatgtact
    14941 gcatgtatgc aaaggacgtc acattaccgt gcagtacagt tgatagcccc ttcccaggta
    15001 gcgggaagca tatttcggca atccagagac agcggcgtta tctggctctg gagaaagctt
    15061 ataacagagg ataaccgcgc atggtgcttg gcaaaccgca aacagacccg actctcgaat
    15121 ggttcttgtc tcattgccac attcataagt acccatccaa gagcacgctt attcaccagg
    15181 gtgaaaaagc ggaaacgctg tactacatcg ttaaaggctc tgtggcagtg ctgatcaaag
    15241 acgaagaggg taaagaaatg atcctctcct atctgaatca gggtgatttt attggcgaac
    15301 tgggcctgtt tgaagagggc caggaacgta gcgcatgggt acgtgcgaaa accgcctgtg
    15361 aagtggctga aatttcgtac aaaaaatttc gccaattgat tcaggtaaac ccggacattc
    15421 tgatgcgttt gtctgcacag atggcgcgtc gtctgcaagt cacttcagag aaagtgggca
    15481 acctggcgtt cctcgacgtg acgggccgca ttgcacagac tctgctgaat ctggcaaaac
    15541 aaccagacgc tatgactcac ccggacggta tgcaaatcaa aattacccgt caggaaattg
    15601 gtcagattgt cggctgttct cgtgaaaccg tgggacgcat tctgaagatg ctggaagatc
    15661 agaacctgat ctccgcacac ggtaaaacca tcgtcgttta cggcactcgt taatcccgtc
    15721 ggagtggcgc gttacctggt agcgcgccat tttgtttccc cccgatgtgg cgcagactga
    15781 tttatcaccc cgatatcaac tatgcacttc gacaaacgct ggtgctatgt ttgcccgtgg
    15841 ccgttgggtt aatgcttggc gaattacgat tcggtctgct cttctccctc gttcctgcct
    15901 gttgcaatat tgcgggcctt gatacgcctc ataaacgttt tttcaaacgc ttaatcattg
    15961 gtgcgtcgct gtttgccacc tgtagcttgc tgacacagct actactggca aaagatgttc
    16021 ccctgccctt tttgctgacc ggattaacgc tggtacttgg cgtcactgct gagctggggc
    16081 cattgcacgc aaaattgctt cctgcatcgc tgctcgccgc catttttacc ctcagtttgg
    16141 cgggatacat gccggtctgg gaaccgttgc tcatctatgc gttgggcact ctctggtacg
    16201 gattgtttaa ctggttttgg ttctggatct ggcgcgaaca accgctgcgc gagtcactaa
    16261 gtctgctgta ccgtgaactg gcagattatt gtgaagccaa atacagcctg cttacccagc
    16321 acaccgaccc tgaaaaagcg ctgccgccgc tgctggtgcg ccagcaaaaa gcggtcgatc
    16381 taattaccca gtgctatcag caaatgcata tgctttccgc gcaaaataat actgactaca
    16441 agcggatgct gcgtattttc caggaggcgc tggatttaca ggaacatatt tcggtcagtt
    16501 tgcatcagcc ggaagaggtg caaaagctgg tcgagcgtag ccatgcggaa gaagttatcc
    16561 gctggaatgc gcaaaccgtc gccgctcgcc tgcgcgtgct ggctgatgac attctttacc
    16621 atcgcctgcc aacgcgtttt acgatggaaa agcaaattgg cgcactggaa aaaatcgccc
    16681 gccagcatcc ggataatccg gttgggcaat tctgctactg gcatttcagc cgcatcgccc
    16741 gcgtgctgcg cacccaaaaa ccgctctatg cccgtgactt actggccgat aaacagcggc
    16801 gaatgccatt acttccggcg ctgaaaagtt atctgtcact aaagtctccg gcgctacgca
    16861 atgccggacg actcagtgtg atgttaagcg ttgccagcct gatgggcacc gcgctgcatc
    16921 tgccgaagtc gtactggatc ctgatgacgg tattgctggt gacacaaaat ggctatggcg
    16981 caacccgtct gaggattgtg aatcgctccg tgggaaccgt ggtcgggtta atcattgcgg
    17041 gcgtggcgct gcactttaaa attcccgaag gttacaccct gacgttgatg ctgattacca
    17101 ccctcgccag ctacctgata ttgcgcaaaa actacggctg ggcgacggtc ggttttacta
    17161 ttaccgcagt gtataccctg caactattgt ggttgaacgg cgagcaatac atccttccgc
    17221 gtcttatcga taccattatt ggttgtttaa ttgctttcgg cggtactgtc tggctgtggc
    17281 cgcagtggca gagcgggtta ttgcgtaaaa acgcccatga tgctttagaa gcctatcagg
    17341 aagcgattcg cttgattctt agcgaggatc cgcaacctac gccactggcc tggcagcgaa
    17401 tgcgggtaaa tcaggcacat aacactctgt ataactcatt gaatcaggcg atgcaggaac
    17461 cggcgtttaa cagccattat ctggcagata tgaaactgtg ggtaacgcac agccagttta
    17521 ttgttgagca tattaatgcc atgaccacgc tggcgcggga acaccgggca ttgccacctg
    17581 aactggcaca agagtattta cagtcttgtg aaatcgccat tcagcgttgt cagcagcgac
    17641 tggagtatga cgaaccgggt agttctggcg atgccaatat catggatgcg ccggagatgc
    17701 agccgcacga aggcgcggca ggtacgctgg agcagcattt acagcgggtt attggtcatc
    17761 tgaacaccat gcacaccatt tcgtcgatgg catggcgtca gcgaccgcat cacgggattt
    17821 ggctgagtcg caagttgcgg gattcgaagg cgtaatgcag gctaaaccat cggataaggc
    17881 attcacgccg catccgacat cttttgcctg atgcttcgta tttacgcccc aaccaccttc
    17941 gccaccgcgt gggcgaaacg ttgcatccct tcatcgatat ccgcatcttc caccaccagc
    18001 gacggtgcaa aacgcatcac atccggtccg gcattcagca ccattacgcc agcctctgcg
    18061 cccgcataca ggaaatcacg cgcccgacct ttgtactgtg gtttcagctc tgcgccaatc
    18121 aacagcccca taccgcgaat atcgctaaat acatcgtact gctgatcgat cttctgcaga
    18181 tggtcaacaa aacgctggcg tttcgcctga atgccttcca gcacttcagg ggtattgatg
    18241 atatcaaacg ccgcccccgc tactgcacag gccagaggat taccgccgta ggtggaaccg
    18301 tgagaaccag gatgaaacgc agaagcaatt tccgccgtgg tcagcatggc gctaatcggg
    18361 aagccgccgc ctaacgcttt cgcagaggtc agaatatccg gcgtaacgcc gtagtgcatg
    18421 taagcaaaca aatcgccggt ccgccccatc ccgcactgca cttcatcaaa caccaataat
    18481 gcctgatgtt gatcgcacag ctcgcgcaag ccctgcaaaa actctggcgt cgctgccgtc
    18541 acaccgccct cgccctggat cggctcaacc accaccgcac aggtgtgatc atccatcacc
    18601 gctttcactg catggagatc gttaaaggga acgtggatga tgtctgccgg tttcggccca
    18661 aagccgtcgg aatattttgg ctgcccaccc accgaaacgg taaacagcga gcgaccatga
    18721 aaagcgttat ggaaggcaat aattttggtt ttgaacgggc tatgacgcac acaggcgtaa
    18781 tggcgtgcca gtttaaaggc ggtttcgtta gcttccgtgc cggagttcat aaacaccacg
    18841 cgttcggcaa acgttgcctc aatcagttta cgcccaagac gcagcgccgg ttcattggtg
    18901 aaaacgttac tgatatgcca cagagtttcg ccctgggttt ttaacgcgtt caccagcgca
    18961 ggatggcaat ggcccaacgc cgtaactgca atgccacccg cgaaatcgac atactccttg
    19021 ccttgctgat cccagattcg gctgccctga ccttttaccg gaataaactc tgccggagca
    19081 taaatcggca ggatcacttc atcgaaagtc gcgcgtgtaa ttgctgtttg ttcaattgcc
    19141 atctcatgat caccctgtta cgcataaaca aatgtgaaat tataaccaca aaatatgcat
    19201 aaaaaatcac taaatggcaa tcagaaatca gcgatgcagg aaattagcca gcagttgatg
    19261 tccttgttcg ctaagaatac tttctggatg gaactgcaca ccttccagat cccactggcg
    19321 atggcgaatc cccataatct cgcgggtttc gctccaggcc gtcacgtcaa agcacgctgg
    19381 taatgagtca ggttccacca ccagcgaatg gtagcgtgtc acggtaagtg gatttgccag
    19441 cccccgaaat acgccctcac cgttatgtgt aatcggcgag gttttgccgt gcatgacctt
    19501 tgcggcgcgc acaactttac cgccaaatgc ctgcgccatt gcctgatgac cgaggcagac
    19561 gccaagaatc ggcaagcgcc cggcatagtg gcgaataacg tcaagggaga tcccggcttc
    19621 atctggcgta caggggccag gtgagatgac aattttttgt ggtttaaggg cgtcgatatc
    19681 cgccagcgtc aacgcatcgt tgcgcttaac cagcacatcc gcccccagtt cacaaaagta
    19741 ctggtagagg ttccaggtaa aagaatcgta gttatctata agcaggatca tggcggctcc
    19801 ggtacaaaag aaccgcgcta ttttactcag attccccggc ttcgcttacc actttgctaa
    19861 atatcatctg cagtgcggtg agatccccca ttgccccact ctgatttgcc tgattccagg
    19921 cctctttttc gataccctgc cagctcagtt gatatccggc atgaatcgcc agttgctcga
    19981 agaagatccg ctgtgccaga ccacttccca cccggaaggg atgcagcacg ttgatttcac
    20041 aatagtaatg cgccagccgc tcgacgaact tcgctttctc caggccaacc agataacctt
    20101 cttcctccag atcctgcatc agggcattgc cctctttttc gatataagca aagtggcaga
    20161 acggcgtatc accctgataa atatcaactt cacgcagttg ccctgcccag tcgaaaatat
    20221 cctgatacag ctggcgatgg atagttcgca aatgcggtaa accgcgcacc agcggaccaa
    20281 gctcaatggt cgcagcacgc agcgccgtca tttcgtaagc ggcctgttcc agccgctgct
    20341 gctggcggat gttcagccgg ttacgcatga tatcaaggcc tggataaaga tacggatcgc
    20401 gcccttcgcc gaatttatcg ctcatagtga ctcctcagct cttcaaggcg cgctaaagcc
    20461 tctgcggcag taagagtgac taaaggcatc tcgacgcctt caagacggcg actggcctga
    20521 aaattacgat tacgctgaag ctcccagaga cgggactttt gcttatcggt gagtttcttc
    20581 acttgatgcc tccctgaacg tgtccatttg ccacaagtat aagcggcaaa tccgggttac
    20641 gccgggagag cagaagcgcg ggcaagattg cccgcgcgag aaatcattac ggcaggactt
    20701 tagcggaaag gataactacc ggttttgacg gcacattctg gtacggacca acgtcatgag
    20761 tcggcacctg ggaaatctta tcggcaacgt ccatgccttt caccacttta ccaaataccg
    20821 cgtaaccgaa atcacgctga ccatggtcaa ggaaggcgtt atcggcaacg ttgataaaga
    20881 actggctggt ggcgctgtct ttgtcagcgg tacgtgccat cgcgatggtg ccacgcgtgt
    20941 tgcgcaggcc gttatcggct tcatttttga ttggcgggtt tggttttttc tgctgcatct
    21001 gctcggtgaa accgccgccc tgaatcataa agccaggaat gacgcggtga aaggtagtgt
    21061 tgttataaaa accgctgttc acataatcga caaagttttg cacagacact ggcgcttttt
    21121 gtttatccag ctccagttcg atgttaccag ctgaggttgt caacaatacg tgcgggtccc
    21181 ctttcgctgc cattgctgcg ggagaaagag cagaaagagc gaaaacagca gccatcgccg
    21241 ccagggtcga tttgaacatg agatttcctt aacaaacaga gcagaaaaaa agcaagtgaa
    21301 gagattctaa atagccttca agaacaaggc catcccttta cctaatttta cgtatctgaa
    21361 atatatgtaa cctgacgatc actttttatt ccgtgatcaa aatcacctct taaaatgcaa
    21421 tttagcaacc gattgcaata aaacatttaa acagatcaca aaatcaccta aaatcgcccg
    21481 ctcgcggcat atcccgctat gccattttat ttttgaacgc aggccaatca tgactaacag
    21541 caatcgcatc aagctcacat ggattagctt tctctcctac gcactgactg gtgcgttggt
    21601 tattgtcacc gggatggtga tgggaaatat cgccgattat ttcaatctgc ctgtttccag
    21661 tatgagtaat accttcacct tcctcaacgc cggcatttta atctctatct tcctcaacgc
    21721 ctggctgatg gaaatcgtcc cgttgaaaac gcagttacgt tttggctttc tcctgatggt
    21781 gctggcggtt gccggtttga tgttcagcca cagcctggcg ctgttctcgg cggcgatgtt
    21841 cattctcggg gtggtcagcg gcatcaccat gtcgattggt acattcctgg taacacaaat
    21901 gtatgaaggg cgtcagcgcg gttcccgcct gttatttacc gactccttct tcagtatggc
    21961 tgggatgatt ttcccaatga tcgccgcgtt tctactggcg cgcagcattg agtggtactg
    22021 ggtttatgcc tgcatcgggc tggtgtatgt cgctattttt attctgacct tcggctgtga
    22081 gttcccggcg ctgggcaaac atgcgccaaa aacggatgct ccggtagaga aagaaaagtg
    22141 ggggatcggc gtactgtttc tctctgttgc ggcgttgtgc tacatcctcg gtcagttagg
    22201 ttttatctcc tgggtgcctg agtatgccaa aggcctgggc atgagcctga acgacgcggg
    22261 cacgctggtg agtaacttct ggatgtcata catggtcggc atgtgggcgt tcagctttat
    22321 tcttcgcttc tttgatttgc aacgcattct gaccgtactg gctggtctgg ctgcgattct
    22381 gatgtacgtc tttaacaccg gaacaccagc acatatggcg tggtcaattc tcgctctggg
    22441 cttcttctcc agcgcgatct ataccaccat catcaccctg ggttcacagc agaccaaagt
    22501 accgtcgcca aaactggtta actttgtcct gacctgcgga accatcggta ctatgttgac
    22561 ctttgtggtt accggcccga tcgttgaaca tagcggtccg caggcggcac tgcttacagc
    22621 aaacggtctg tacgctgtcg tctttgtgat gtgcttcctg ttaggtttcg tcagccgtca
    22681 ccgtcagcat aacaccctga cctctcatta attgctcatg ccggacggca ctatcgtcgt
    22741 ccggcctttt cctctcttcc cccgctacgt gcatctattt ctataaaccc gctcattttg
    22801 tctatttttt gcacaaacat gaaatatcag acaattccgt gacttaagaa aatttataca
    22861 aatcagcaat atacccatta aggagtatat aaaggtgaat ttgatttaca tcaataagcg
    22921 gggttgctga atcgttaagg taggcggtaa tagaaaagaa atcgaggcaa aaatgagcaa
    22981 agtcagactc gcaattatcg gtaacggtat ggtcggccat cgctttatcg aagatcttct
    23041 tgataaatct gatgcggcca actttgatat taccgttttc tgtgaagaac cgcgcatcgc
    23101 ttatgaccgc gtacacctct cgtcttactt ctctcaccac accgccgaag agctgtcgct
    23161 ggtgcgcgaa ggcttctacg agaaacacgg catcaaagtt ctggtcggcg aacgcgctat
    23221 caccatcaac cgtcaggaga aggtgattca ctccagcgcc ggacgtaccg ttttttatga
    23281 caagctgatc atggcaaccg gttcctaccc gtggatcccg ccaatcaaag gttctgatac
    23341 tcaggactgc tttgtctatc gcactattga agacctcaac gccattgaat cctgcgcccg
    23401 tcgcagcaaa cgcggtgccg ttgttggtgg cggcctgtta ggtctggaag ccgcaggcgc
    23461 gctgaaaaac ttaggtattg aaacccacgt tatcgaattt gcccctatgc tgatggcaga
    23521 acagcttgat cagatgggcg gcgagcagct gcgtcgcaaa atcgaaagta tgggcgtgcg
    23581 cgttcacacc agcaaaaaca cccttgagat tgtgcaggaa ggtgttgaag cgcgtaaaac
    23641 catgcgtttt gccgacggca gcgaactgga agtcgacttt atcgtcttct ctaccggtat
    23701 ccgtccgcgc gataagctgg caacccagtg tggtctggac gttgctccgc gtgggggtat
    23761 tgtcattaat gattcctgcc agacttccga tccggatatc tacgccatcg gtgaatgcgc
    23821 aagctggaac aaccgtgtat ttggtctggt agcacctggc tacaaaatgg cgcaggtcgc
    23881 cgttgaccat attctcggta gcgaaaacgc ctttgaaggt gctgacctta gcgccaagct
    23941 gaaactgctg ggcgtagacg taggcggtat tggtgatgcg cacggtcgca cgcctggcgc
    24001 acgtagctac gtttacctcg acgaaagtaa agagatctac aaacgcctga ttgtcagcga
    24061 agacaacaaa accctgctcg gtgcggtact ggtgggcgat accagcgact acggtaacct
    24121 gctgcaactg gtgctgaacg ctatcgaact gccggaaaac ccggattccc tgatcctgcc
    24181 agcacactcg ggtagcggca agccgtctat cggtgttgat aaactgccgg acagcgcgca
    24241 aatctgctcc tgcttcgacg tcaccaaagg tgatctgatt gctgccatca acaaaggctg
    24301 ccacacagtt gcggcgctga aagctgaaac caaagcgggt actggctgcg gtggctgtat
    24361 cccgctggtc actcaggtac tgaacgcgga actggcgaaa cagggcatcg aagttaacaa
    24421 caacctgtgc gaacactttg cttattcgcg tcaggaactg ttccatttga tccgcgttga
    24481 aggcattaaa accttcgaag aactgctggc gaaacacggc aaaggctacg gttgtgaagt
    24541 ttgtaaacca accgtcggtt cgctgctggc ctcctgctgg aacgaataca ttctgaagcc
    24601 ggaacatact ccgctgcagg attctaacga caacttcctc gctaacatcc agaaagacgg
    24661 cacctactcg gtgatcccgc gttctccggg cggtgaaatc accccggaag ggctgatggc
    24721 ggtaggtcgt atcgcgcgtg aatttaatct ctacaccaag atcactggct cccagcgtct
    24781 ggcgatgttt ggcgcacaga aagacgatct gccggagatc tggcgtcagc tgattgaagc
    24841 cggcttcgaa accggtcatg cctatgcgaa agcactgcgt atggcgaaaa cctgcgtggg
    24901 tagcacctgg tgccgctacg gcgttggcga cagcgtcggc ctcggcgtgg aactggaaaa
    24961 ccgctacaaa ggcatccgta cgccgcacaa aatgaagttc ggtgtctccg gctgtacccg
    25021 tgaatgttca gaagctcagg gtaaagacgt gggtattatc gccactgaaa aaggctggaa
    25081 cctgtatgtt tgcggtaacg gcggcatgaa accgcgtcat gcggatctgc tggcggcgga
    25141 tatcgatcgc gaaacgctga tcaaatatct cgaccgcttc atgatgttct acatccgtac
    25201 tgccgacaaa ctgacgcgta ccgcaccgtg gttagaaaac ctcgaaggcg gcatcgatta
    25261 cctgaaagca gtgatcattg acgacaaact ggggctgaac gcacatctgg aagaagagat
    25321 ggcgcgcctg cgtgaagcgg tactgtgtga gtggactgaa acggtcaata cgccgtctgc
    25381 gcagactcgc ttcaaacact tcatcaacag cgacaagcgt gacccgaacg tgcagatggt
    25441 gccagagcgc gaacagcacc gtccggcaac gccgtatgaa cgtatcccag taactctggt
    25501 ggaggacaac gcatgagcca gtggaaagac atctgcaaaa tcgatgacat cctgcctgaa
    25561 accggcgtct gcgcgctgtt aggtgacgag caggtcgcga ttttccgccc gtatcacagc
    25621 gatcaggtgt ttgcgatcag caacatcgac ccgttcttcg agtccagcgt gctgtcacgc
    25681 ggactgattg cggaacacca gggcgagctg tgggtcgcca gcccgctgaa aaaacagcgt
    25741 tttcgcttaa gcgacggctt gtgcatggaa gacgaacagt tttccgtcaa acattacgaa
    25801 gcgcgagtga aagacggcgt ggtgcagctg cgcggttaat gttttaacgg gaggcgcaat
    25861 gcctcccctt tttgcatggt cctgtaataa tcttcggtat attgcaggac attttttaaa
    25921 ctttttgttt tattttttgt ttttattttt taaaggataa tcaaatgttt acagacacta
    25981 ttaataagtg tgcggctaac gctgcgcgca ttgcacgcct gtcggcaaat aacccgctcg
    26041 gcttttgggt cagctccgcc atggcgggcg cgtatgtggg tcttgggatc atcctgattt
    26101 tcacgctcgg taatttgctc gatccatccg tacgcccttt ggtgatgggc gcgacctttg
    26161 gtatcgcctt aacgctggtg attatcgccg gttctgaact gttcaccgga cacaccatgt
    26221 tcctcacctt tggggtaaaa gcgggcagca tcagccacgg gcaaatgtgg gcaatcctgc
    26281 cgcaaacctg gctgggtaac ctggtcggtt ccgtcttcgt tgccatgctc tatagctggg
    26341 gcggcggtag cctgctgccg gtagatacca gcatcgttca ctccgtcgcg ctggctaaaa
    26401 ccactgcacc ggcaatggta ctcttcttca aaggtgcatt gtgtaactgg ctggtttgcc
    26461 tggcaatctg gatggcgctg cgcactgaag gggcggcgaa atttatcgct atctggtggt
    26521 gtctgctggc atttatcgcg tccggctacg agcactctat cgctaacatg acgctgttcg
    26581 cgctctcctg gttcggcaac cacagcgaag cctacacgct ggcgggtatt ggtcataacc
    26641 tgctgtgggt gacgctgggt aatactttat caggtgccgt attcatggga ttgggttatt
    26701 ggtatgctac gccgaaagcg aatcgtccgg ttgcggacaa atttaatcaa actgaaacgg
    26761 ctgccggtta attactaagg ggtttttacg tggatcattt gcctatattt tgccaattac
    26821 gcgatcgcga ctgtctgatt gtcggcggtg gtgatgtcgc ggaacgcaaa gcaaggttgc
    26881 tgttagacgc aggcgctcgc ttaacggtga atgcattagc gtttattcca cagttcaccg
    26941 catgggcaga tgcaggcatg ttaaccctcg tcgaagggcc atttgatgaa agccttctcg
    27001 acacctgctg gctggcgatt gcagcgacgg atgatgacgc gcttaaccag cgcgtcagcg
    27061 aagccgctga agctcgtcgc atcttctgta acgtggtcga tgcgccgaaa gccgccagct
    27121 ttattatgcc gtcgattatt gaccgctcac cgctcatggt agcggtctcc tctggcggca
    27181 cctctccggt tctggcacgc ctgttgcgcg aaaaacttga atcactgctg ccgttacatc
    27241 tgggccaggt agcgaaatac gccgggcaat tacgcgggcg agtgaaacaa cagttcgcca
    27301 cgatgggtga gcgtcgccgt ttctgggaga aattgttcgt taacgaccgc ctggcgcagt
    27361 cgctggcaaa caacgatcag aaagccatta ctgaaacgac cgaacagtta atcaacgaac
    27421 cgctcgacca tcgcggtgaa gtggtgctgg ttggtgcagg tccgggcgat gccgggctgc
    27481 tgacactgaa aggactgcaa caaattcagc aggcagatgt ggtggtctac gaccgtctgg
    27541 tttctgacga tattatgaat ctggtacgcc gcgatgcgga ccgtgttttc gtcggcaaac
    27601 gcgcgggata ccactgcgta ccccaggaag agattaacca gatcctgctg cgggaagcgc
    27661 aaaaaggcaa acgcgtggtg cggctgaaag gtggcgatcc gtttattttt ggccgtggtg
    27721 gcgaagagct ggaaacactg tgcaacgcgg gtattccgtt ctcggtggtt ccgggtatta
    27781 ccgcagcttc tggttgctct gcctattcgg gtattccact cacgcatcgc gattatgccc
    27841 agagcgtacg cttaattacc ggacacttaa aaaccggtgg cgagctggac tgggaaaacc
    27901 tggcggcaga aaaacagacg ctggtgttct atatggggtt gaatcaggcc gcgactattc
    27961 agcaaaagct gattgaacac ggaatgccag gcgaaatgcc ggtggcaatt gtcgaaaacg
    28021 gtacggcagt cacgcagcgc gtgattgacg gtacgctcac acagctggga gaactggcgc
    28081 agcaaatgaa cagtccatcg ctaattatta ttggtcgggt tgttggcctg cgcgataaac
    28141 tgaactggtt ctccaaccat taatttaacc cgggccagag aattctggcc ttcttaatga
    28201 ctctttttat atattcagca aataaaacat agccccttaa taaatattat ctgctaatgg
    28261 gttatattca ccgttacagc gacttacaaa attaagtcat tcgctcactg acgccaatta
    28321 aatattcctg tatcgttctt aacgagcagt ctg
//
LOCUS       DAPHKZ010000052        28234 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.052, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000052 DAPHKZ010000000
VERSION     DAPHKZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28234
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.052"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..697
                     /locus_tag="RH288_002379"
     CDS             <1..697
                     /locus_tag="RH288_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDV4031426.1"
                     /translation="NSNKLDFQHEARILNGIWLITALGLVATAGLAWGAKYLEITATK
                     YDSPPMYVAIGLLLLCMYGLSKDINKINAAIAGVIYLFLLSLVAIVVASLVPVYAIII
                     VFSTAGAMFLISMLAGLLFNVDPGSHRFIIMMTLTGLALVIIVNAALMSERPIWVISC
                     LMIVLWSGIISHGRNKLLELAGKCHSEELWSPVRCAFTGALTLYYYFIGFFGILAAIA
                     ITLVWQRHTRFFH"
     gene            complement(733..1689)
                     /locus_tag="RH288_002380"
     CDS             complement(733..1689)
                     /locus_tag="RH288_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HDV4031427.1"
                     /translation="MSKSHPRWRLAKKILTWLFFIAVIVLLVVYAKKVDWEEVWKVIR
                     DYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKLAKRQVMLVSFICYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLAGIIFTAGVVELPDHWYVD
                     QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMV
                     MGAIIWLLLGQSVNYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFIALLAGEHTSKGT
                     IIAALLAYRVLYYFIPLLLALICYLLLESQAKKLRAKNEAAM"
     gene            complement(1689..2930)
                     /gene="clsB"
                     /locus_tag="RH288_002381"
     CDS             complement(1689..2930)
                     /gene="clsB"
                     /locus_tag="RH288_002381"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HDV4031428.1"
                     /translation="MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFE
                     DDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLF
                     GMRTNVFRRMHRKIVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
                     QFELENLPGQSAARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQ
                     ARREVIIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVK
                     GGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRD
                     NLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDP
                     PAQPTMETQDRVETENTGVKP"
     gene            complement(2927..3688)
                     /locus_tag="RH288_002382"
     CDS             complement(2927..3688)
                     /locus_tag="RH288_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDV4031429.1"
                     /translation="MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADI
                     VCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
                     VNELPDGEPVLVAGDFNDWRQKANHPLKVQAGLDEIFTRAHGRPARTFPVQFPLLRLD
                     RIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL"
     gene            3821..4231
                     /locus_tag="RH288_002383"
     CDS             3821..4231
                     /locus_tag="RH288_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HDV4031430.1"
                     /translation="MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGL
                     CALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLL
                     AIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR"
     gene            complement(4193..5299)
                     /locus_tag="RH288_002384"
     CDS             complement(4193..5299)
                     /locus_tag="RH288_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4031431.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFP
                     ADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISS
                     LCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM"
     gene            complement(5310..6443)
                     /locus_tag="RH288_002385"
     CDS             complement(5310..6443)
                     /locus_tag="RH288_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4031432.1"
                     /translation="MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFG
                     YGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRG
                     LVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
                     FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLS
                     TEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTL
                     GMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFV
                     STLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            complement(6436..8172)
                     /locus_tag="RH288_002386"
     CDS             complement(6436..8172)
                     /locus_tag="RH288_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415315.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4031433.1"
                     /translation="MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGA
                     GKTTLMRMLAGLLKPDSGSATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GEPKALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPD
                     DIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKE
                     LTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMD
                     LKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGL
                     KSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQ
                     LIHDWDKEHSNE"
     gene            complement(8165..9160)
                     /gene="hlyD"
                     /locus_tag="RH288_002387"
     CDS             complement(8165..9160)
                     /gene="hlyD"
                     /locus_tag="RH288_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HDV4031434.1"
                     /translation="MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTV
                     NLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRA
                     VEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE"
     gene            complement(9163..9834)
                     /gene="cecR"
                     /locus_tag="RH288_002388"
     CDS             complement(9163..9834)
                     /gene="cecR"
                     /locus_tag="RH288_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415317.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CecR"
                     /protein_id="HDV4031435.1"
                     /translation="MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQN
                     IAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRA
                     CRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
                     NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGL
                     SQRSL"
     gene            10063..11427
                     /gene="rhlE"
                     /locus_tag="RH288_002389"
     CDS             10063..11427
                     /gene="rhlE"
                     /locus_tag="RH288_002389"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HDV4031436.1"
                     /translation="MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
                     MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD
                     QVTQHVHFVDKKRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPGYEPDPSIKAEPIQNGRQ
                     QRGGGGRGQGGGRGQQQPRRGEGGAKSASAKPAEKPSRRLGDAKPAGEQQRRRRPRKP
                     AAAQ"
     gene            complement(11659..12141)
                     /gene="ybiA"
                     /locus_tag="RH288_002390"
     CDS             complement(11659..12141)
                     /gene="ybiA"
                     /locus_tag="RH288_002390"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-glycosidase YbiA"
                     /protein_id="HDV4031437.1"
                     /translation="MPVRAQRIQHVMQDTIINFYSTSDDYGDFSNFAAWPIKVDGKTW
                     PTSEHYFQAQKFLDEKYREEIRRVSSPMVAARMGRDRSKPLRKNWESVKEQVMRKALR
                     AKFEQHAELRALLLATAPAKLVEHTENDAYWGDGGHGKGKNRLGYLLMELREQLAIEK
                     "
     gene            12261..14411
                     /gene="dinG"
                     /locus_tag="RH288_002391"
     CDS             12261..14411
                     /gene="dinG"
                     /locus_tag="RH288_002391"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HDV4031438.1"
                     /translation="MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAG
                     EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKK
                     IIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLK
                     GDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAE
                     VVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQL
                     DLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEH
                     RFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRA
                     LGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWR
                     SIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVE
                     PSIDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGD
                     QPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVI
                     TEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKR
                     LLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR"
     gene            14439..15401
                     /gene="ybiB"
                     /locus_tag="RH288_002392"
     CDS             14439..15401
                     /gene="ybiB"
                     /locus_tag="RH288_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HDV4031439.1"
                     /translation="MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGG
                     VLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLA
                     ILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
                     FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDI
                     GGRALLMHGTEGEVYANPQRCPQINLIDREGMRVLYEKQDTAGSELLPQAKDPETTAQ
                     WIERCLAGSEPIPESLKIQMACCLVATGEAATISDGLARVNQAF"
     gene            15542..16627
                     /gene="hcxB"
                     /locus_tag="RH288_002393"
     CDS             15542..16627
                     /gene="hcxB"
                     /locus_tag="RH288_002393"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcXB"
                     /protein_id="HDV4031440.1"
                     /translation="MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAG
                     HDSHGIGMIPSYVRSWSQGHLQINHHAKTVKEAGAAVTLDGDRAFGQVAAHEAMALGI
                     EKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
                     GTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPA
                     VMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTII
                     INPELFGAPDCNAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQKQGIPLDAGS
                     WQAICDAARQIGMPEETLQAFCQQLAS"
     gene            complement(16856..17116)
                     /locus_tag="RH288_002394"
     CDS             complement(16856..17116)
                     /locus_tag="RH288_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV4031441.1"
                     /translation="MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADG
                     ASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSGTAVIYK"
     gene            complement(17381..17647)
                     /gene="ybiI"
                     /locus_tag="RH288_002395"
     CDS             complement(17381..17647)
                     /gene="ybiI"
                     /locus_tag="RH288_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc finger protein YbiI"
                     /protein_id="HDV4031442.1"
                     /translation="MASGWANDDAVNEQINSTIEDAIARARGEIPRGESLDECEECGA
                     PIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRRGSKDSQLR"
     gene            complement(17721..18398)
                     /gene="ybiX"
                     /locus_tag="RH288_002396"
     CDS             complement(17721..18398)
                     /gene="ybiX"
                     /locus_tag="RH288_002396"
                     /EC_number="1.14.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKHD-type hydroxylase YbiX"
                     /protein_id="HDV4031443.1"
                     /translation="MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQ
                     QVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVR
                     SHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
                     TPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGESEEILSLLNLYHNL
                     LREWSEI"
     gene            complement(18440..20722)
                     /locus_tag="RH288_002397"
     CDS             complement(18440..20722)
                     /locus_tag="RH288_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor Fiu"
                     /protein_id="HDV4031444.1"
                     /translation="MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTL
                     VVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVG
                     AFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
                     YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGE
                     KTHDAGRDKVKNERYGVAPSVAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSA
                     PSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVK
                     QDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGH
                     DVSTGVEFTRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYA
                     FDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPTGVAKGSPVTTVDTAK
                     SGNLMNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKA
                     NTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNI
                     TPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGAR
                     YIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKS
                     GYRYHPGEPRTFLLTANMHF"
     gene            complement(20987..21247)
                     /locus_tag="RH288_002398"
     CDS             complement(20987..21247)
                     /locus_tag="RH288_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV4031445.1"
                     /translation="MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATG
                     ASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTATIYK"
     gene            21523..22449
                     /gene="rlmF"
                     /locus_tag="RH288_002399"
     CDS             21523..22449
                     /gene="rlmF"
                     /locus_tag="RH288_002399"
                     /EC_number="2.1.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415328.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
                     /protein_id="HDV4031446.1"
                     /translation="MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSV
                     DFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIP
                     ANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISSNPGLNRAIRLR
                     RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGG
                     QQQELWCEGGEVTFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVV
                     KKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR"
     gene            complement(22446..24671)
                     /gene="ybiO"
                     /locus_tag="RH288_002400"
     CDS             complement(22446..24671)
                     /gene="ybiO"
                     /locus_tag="RH288_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HDV4031447.1"
                     /translation="MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQ
                     KKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEV
                     SRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
                     PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRT
                     IAFQQSLFLNAFALIEFFKAVLRLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIG
                     YGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLA
                     FFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSG
                     MFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFD
                     FWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRT
                     LLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGV
                     FIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGI
                     GSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLSNTAFTL
                     RVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGATPAEPLPPGEPT
                     L"
     gene            complement(24932..25654)
                     /gene="glnQ"
                     /locus_tag="RH288_002401"
     CDS             complement(24932..25654)
                     /gene="glnQ"
                     /locus_tag="RH288_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HDV4031448.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     NPQVLIKNPPSQRLQEFLQHVS"
     gene            complement(25651..26310)
                     /gene="glnP"
                     /locus_tag="RH288_002402"
     CDS             complement(25651..26310)
                     /gene="glnP"
                     /locus_tag="RH288_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HDV4031449.1"
                     /translation="MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFAR
                     TFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            complement(26448..27194)
                     /gene="glnH"
                     /locus_tag="RH288_002403"
     CDS             complement(26448..27194)
                     /gene="glnH"
                     /locus_tag="RH288_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HDV4031450.1"
                     /translation="MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDEL
                     RDKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            complement(27598..28101)
                     /gene="dps"
                     /locus_tag="RH288_002404"
                     /gene_synonym="pexB"
     CDS             complement(27598..28101)
                     /gene="dps"
                     /locus_tag="RH288_002404"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HDV4031451.1"
                     /translation="MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLW
                     FIESNIE"
BASE COUNT         6691 a         7343 c         7516 g         6684 t
ORIGIN      
        1 aaacagcaat aaattagatt ttcagcacga ggccaggata ttaaacggta tatggctcat
       61 taccgcttta ggtttggtgg caaccgcagg actagcctgg ggagctaagt atctcgaaat
      121 tacggcaacc aaatatgatt caccaccaat gtatgtcgcc atagggttat tattactttg
      181 tatgtatggc ttaagtaagg atatcaacaa gataaatgcc gccatcgcgg gcgtaatata
      241 tctgttttta ctctctttgg tggcgattgt cgttgcaagt ttagttcctg tatatgccat
      301 tatcatcgtg ttcagcactg cgggcgcgat gtttttaatc agtatgctgg ccggtttatt
      361 atttaatgtt gatcctggtt ctcaccgttt tatcattatg atgacgttga cagggttggc
      421 cctggtaatc atcgtgaatg cggcattaat gagtgaacgg cccatttggg taataagttg
      481 cttaatgatt gtgttatggt caggcattat ctcgcatgga cgaaataagc tccttgaatt
      541 ggcggggaaa tgccatagtg aagagttgtg gagtccggtt cgttgcgctt ttacaggtgc
      601 attaacactc tattactatt ttatcggctt ctttgggata cttgccgcga tagctataac
      661 gcttgtctgg caaaggcata cgcgtttttt tcattagccg taaatgcaca tactaaagaa
      721 cttaactaaa cttcacatcg ccgcttcatt tttcgcccgt agcttcttcg cctggctttc
      781 cagcaacagg taacagatca gcgccagcag cagtgggata aagtaataca gcacacggta
      841 agcgagtagg gcggcgataa ttgtaccttt ggaggtatgc tccccagcca gtagtgcgat
      901 aaacaccgct tccagcacac cgatccccgc cggaatatgc acgatgacgc cagcaatact
      961 actaaccagt aacacgccca gtacaaagaa atagttcacg ctttgaccaa gtaacagcca
     1021 gataatcgcc cccattacca tccagttaac gctggaaatc agcatctgag cgagggcgaa
     1081 tttccatgaa ggcagcacca gcttttgccc tttgatggtc atatggcggt gcttcgcgaa
     1141 agcgcaaaac cacaaataaa ccgcgataat catcagtaag ccaatgccga gaatacgcag
     1201 cgtagtttga tcgacatacc agtgatccgg caactccacc acgcctgcgg taaagataat
     1261 ccctgccagt aaaatgtagc ccagccagtt ggtggtaata ctgagcgaga aaatccgcgt
     1321 aatagtgcta ccgggcaacc ccagacgaga gtacaaacga tagcgcatac caatgccgcc
     1381 gacccaggta ctgagcgtca ggttgaaggc gtagcagata aacgacacca gcatcacctg
     1441 gcgcttcgcc agtttgtgac cgcagtaaaa gcgggcgagc aggtcatagc agccgtaaat
     1501 cagatagctg acgaccacca gcccgaccgc actaagcagc gcaacgcgat tgtagtcgcg
     1561 gatgaccttc cagacctctt cccagtccac ttttttggcg tagaccacca gcaacacaat
     1621 caccgcgata aaaaacagcc aggtgaggat cttctttgct aagcgccagc gcgggtgtga
     1681 tttactcatc agggttttac ccccgtgttt tcagtttcta cccgatcctg cgtttccatt
     1741 gtcggttgtg cgggcggatc aacctgcgcc agacgtggcg tgtgtgccgg aagccagcca
     1801 accagcgccg ggaagtggcg taaaaagtgg aacgccagca cgcttttggt caggttccac
     1861 caggtgcgtt tgggcagcat ggtttcatcc acctgctgac aatctgcggc aataatgccg
     1921 ttcagattat cgcgcagcgt ctggttaaaa tgacgatcgt ggatgatgac atttgcttcg
     1981 agattcagtg acaaactgag cggatcgaga ttactggacc ctactgtcgc ccagtgatcg
     2041 tccatcaatg ccactttgcc gtggagcggg cggcggcggt actcaaaaac ctgaacgccg
     2101 cctttaacca gatagttata cagcaagcgc gcaccgactc tgacaatcgg catatccggt
     2161 tcgccctgaa tgatcagttt gatccgcacc ccgcgccgtg ccgctttacg caaggcgtgt
     2221 aaaaatcgat agccggggaa gaagtaggcg ttggcgataa tcacttcccg ccgcgcctga
     2281 gtgagcattt tcaaataatg gcgttcaata tcatcgcgat gttcttcgtt atcgcgccag
     2341 accagcaata cctgcgcttc tcccggctgg cggttctctt ccgctttgtg atgacgtcgc
     2401 caccagcgtc gtgccgcgct ctgtccaggc aggttttcca gctcaaactg gagaatatct
     2461 tcgacaatcg gcccttcaag gcgtaccgcg taatcctgtt tagcctctgg accgtagctg
     2521 gacatatgct cggcggagta attcagcccg ccaataaagg ctatacgcgc gtcgatcacc
     2581 acaattttgc gatgcatccg gcgaaacaca ttggtgcgca taccaaaaag gcgagggcgg
     2641 ggatcgtagt agcggaacac tacgccagct gccgtcagtt cattgacaaa ctcatcgctg
     2701 agatccggcg aaccgtagcc atccagcaag acttccgctt taaccccgcg ttgcgctgct
     2761 gccagtagtg ccgcatgcag ttgtttgccg acgtcatcct caaaccagat aaacgtttca
     2821 agaatgatgc gttcttgtgc ctcgccaatc gccttaaaca ccgcgggata atattgctcg
     2881 ccgttttcca gcaactggat cttattgcct tcgcgccagc tacatttcat aaatgaatct
     2941 ccgcacttaa aggggcatga tcagaaaggt gtcgccatgt ccgcagcggc aacgcggttg
     3001 gcgcgctggc gctggcattt ttgacgtaga tcctgtccag tcgtagtaga ggaaattgca
     3061 ccggaaacgt gcgcgccggg cgtccgtggg cgcgggtaaa aatctcatcc agtccggcct
     3121 gcacttttaa cggatgatta gctttttgcc gccagtcatt gaaatcaccc gccaccaata
     3181 ccggttcgcc gtccggtagc tcattcaccc attcggcgag catcgcaagc tgcgcctgac
     3241 ggtgcgcctc acgcaggccc agatgtacgc acatcacatg aatcgctttt ccggtcatcg
     3301 gcggcacaat gcggcagtag agcacgccgc gcttttccgc accatcgacc gaaacatcgc
     3361 gattctcata atgttcaatg ggataacgcg acagtacggc gttgccgtga tgcccttccg
     3421 ggtatacggc attgcgaccg taggcaaaat cgctccacat agtgtcggcg agaaactcgt
     3481 agtgcgaggt atcgggccag ttttccacat gcagcggatg aacttcgtgc gcgcccatca
     3541 cttcctgcag gcaaacaata tcggcgctga cggtacgcac ggcgtcgcga agttccggca
     3601 aaatgaagcg tcggttaaac gcggtaaagc ctttgtgaat attgatggtg agcaccttga
     3661 acgaaaattg ttgtgtttga tcgggcataa ttttcctgtc tttgcctctt atctcattga
     3721 aatagtgtag tcggcgtcac aaaaaggtgc ggtcttacgg aattttccgt aaagttcggt
     3781 actctgagta agtagagata aattcttcag gagagaagcc atgaagtggc aacaacgtgt
     3841 tcgtgtcgca acgggtctaa gttgctggca gattatgttg catttactgg tagtggcgct
     3901 gctggtggtg ggctggatga gtaagactct ggttcacgtc ggcgtgggat tatgcgcact
     3961 gtattgtgtc acggtagtga tgatgctggt gtttcagcgc caccccgagc aacgctggcg
     4021 tgaggtggca gacgtgctgg aagagctgac cacgacctgg tattttggcg cagcgctgat
     4081 tgtgctgtgg ctgttgtccc gcgttctgga aaacaacttt ttgctggcaa ttgcagggct
     4141 ggcaatcctt gccggcccgg cggtagtgtc tttgctggcg aaagataaga agttacatca
     4201 ccttacgtct aaacatcgcg tacgccgctg accctgtcgt ggccgttatc accagtagcg
     4261 gccacaaact attccacaca atatccagac tcgcatcctt caaataaatc tgcttggtaa
     4321 tgtccgtaaa gtggcgaata gggttaatcc acgtcaggtt ttgcagccat accggcatgt
     4381 tttccaccgg agaaacgtaa ccggaaagga gaatggcggg catcataaag acaaacacgc
     4441 cgataaacgc ctgctgttgt gttgaacaga gtgatgaaat caacagaccg aatcccacca
     4501 gcgataaacc ataaatcacc atcgtaaagt agaacagcgc cagcgatccg gcgaagggga
     4561 tttgatacgc ccagatacca atcgccagca caatggtggc ctggaaggtg gcgacaatta
     4621 acgccggtac ggctttgccg atgaagatct gccaggtggt gagcggcgaa accagtagct
     4681 gatcgagcgt accttgttca cgttcgcggg cgacggaaag tgaagtgacg atcattacgc
     4741 cgatagtggt gatcatggcg atcagtgacg gcaccacaaa ccatttgtag tcgagattcg
     4801 ggttatacca gttgcgtacc accagctcgc tgttgttagg tttcggtttt ccttccagca
     4861 gctcctgctg ataatttttg acgatctgtt gcaggtagtt ggcggcaatt tgcgcactgt
     4921 tggagttacg cccgtcgagg atcaactgca aaggcgcggt ctggaaggta tccagtttgc
     4981 gcgagaagtc agccgggaaa cgcaccagta gtaacgcctt ttgtgtgtcg atggttgggc
     5041 ggatctcctg tgggcttttc agcagcagca catgagtaaa ggcgctggcg cgggcaaaac
     5101 gttgggtcag ctccaccgaa tgctcgccgt tatcttcatc gtagatggcg atggtggcgt
     5161 tagtcacttc cagcgtggcg gcgaacggga acaggatcac ctgaattagc acgggtaaaa
     5221 tcagaatcgc gcgggtttgc ggttcgcgca gcaacgactg caactctttg cggattaacg
     5281 tccataagcg atgaaacatg ctcttctccc taatccagcc gacgtttggt tttcagccac
     5341 gtcaggccga taaacatcac cgccgaagcg atcaaaaaca gcacgtttac caccagcacc
     5401 actggaatat tcccggcgag gaacaggctt tgcagggtgc tgacgaaata acgagcggga
     5461 ataatgtacg tcaccgcgcg gatcaccgcg ggcatactgt cgatctgaaa aataaagccg
     5521 gaaagcataa tcgacggcag aaaagcggcg ttcagggcga cctgagcggc attgaactgg
     5581 ttgcgggtaa tcgtggaaat cagcagcccc atccccaggg tactgagtaa aaacaggctg
     5641 gagataaaaa acagaatcag cagcgacccg cgatacggca cgccgagaat aaacactgac
     5701 accagcatac acagcaacat cgccagcatc ccgagaaagt aataagggat cagcttacac
     5761 agcagcagtt ccgtgcgggt aatctccgta gagagcagag cctccatggt gccgcgttcc
     5821 cattctcgcg ccaccaccag cgaggtgaga atcgcgccga tgaccgtcat gataatggtc
     5881 accgcaccgg ggataatgaa gtgctggcta atcgccgccg ggttaaacca gtagcgggtt
     5941 tgtacatcaa taagcggttc aaaagtctgc ccgttgtcct ccgctcgctg catttgccag
     6001 atctgccaga tcccttcgac atacccctgt acaaagttag cggtattcgg ctcactgccg
     6061 tcggtgatca cctgaatcgg tgcggtggcg ttggcgcgct ccatctgttc cgcaaaatcc
     6121 accggaataa ccaccagacc gcgaattttc cccgcctgca ttttggcgat cagttcctga
     6181 cggttatcgc tgatggtggc gtcgatgtag ggcgaaccgg tcatggtgtg ggtgaaatcc
     6241 agcgccgctt cgctacgctg ttccagtaaa atcccgaccc gcagcttgct ggagtcgagg
     6301 ttaatgccgt aaccaaaaat aaacagcagt agcagcggga tcactaccgc aatcagccag
     6361 ctactcggat cgcgaacgat ctgccgcgtc tctttaacgc acagcgcccg tacgcgacgc
     6421 caggacagga tcgggttact cattgctatg ctccttatcc cagtcgtgga tcaactgaat
     6481 aaaggcttgc tccatggtgg gatcgggttg ctcatcgtta gccgactgtg ctttcaaatc
     6541 gtccggcgtg ccgctggcga ttaatttccc gcggtacacc aggccgatgc ggtcgcaata
     6601 ttccgcttca tccataaagt gggtggtgac catcaccgtg acgcctttct ctaccatgct
     6661 gttgatgtgc agccaaaatt cacggcgggt gagggggtca acgccggaag tcggttcgtc
     6721 gagaaacaga atgtccggtt catgcatcag cgaacaggcc agcgccagcc gctgtttaaa
     6781 acctaatggc agttcatcgg tggcgtggga ggcgatactt ttcaggccga acgcctcgct
     6841 catgcgggag attttttcgt tctgcgcccg accgcgtaag ccatacacac cagagaaaaa
     6901 gcgtaaattc tgttcgaccg tcaggttacc gtagagcgaa aatttttgcg ccatatagcc
     6961 gagatgctgg cgcgctttac cggaactctc tttcagatcc atccccagca ccagcgcctg
     7021 gccggaagtc ggcaccagca aaccgcacat catcttaaag gtggtcgatt tacccgcgcc
     7081 gtttggcccc agcaaaccaa aaatctcccc acgtttaacg gcaaagttga cgtgatcggt
     7141 ggcggcaaaa tccccaaatt tcttggtcag ttctttcgct tcgatcaccg tctcgccggg
     7201 tgtgccttct accgtatgta atattgcgcc cagcggcgat tccgaggttc cggcaccgcc
     7261 cagcaaatca ataaacgcat cttcaaaacg cggcgtagtt tcgttgatgt tgatttccgg
     7321 catcccgtcg gcatggcgaa tatcgtctgg tgtggcctct tttttgagga tcagacgtac
     7381 cgatttcccc tgaatcatgc cgtcgctgac ctgcggcagt ttcaaggcgc gttgcaacag
     7441 tttgcggttg ccctcgtgtg gactggtcat cagaaagctg cgtccggcca tggtttgtgt
     7501 cagggctttt ggttctccct gatacagcaa ctcgccttcg ttcatcagta acacgtcacg
     7561 gcactgctcg gcttcgtcga gatacgaggt actccagagg attaacatcc cttcgcccgc
     7621 cagctcatgc accatctgcc acagttcgcg ccgtgagata gggtcaacgc cgacgccggg
     7681 ttcatcgagc agcaacactt tcggttcgcc caccagggta caggccaggc cgagtttttg
     7741 tttcatccca ccggagagct tgcccgccag gcgtccggta aacggcccaa gagacgtaaa
     7801 ctccagcagg cgagcaaaag tttgcttacg tgcctcgccg gtgacgctgc gcaaatccgc
     7861 gtacagattg aggttctcca tcaccgtgag atcttcatac agaccaaatt tctgcggcat
     7921 ataaccgagc acggcgtgca gcgcgccgtc gtttttgatc ggatcaaagc caatcaccgt
     7981 ggcactgccg ctgtcgggtt tcagtaatcc cgccaacatc cgcatcagcg tggttttacc
     8041 tgcaccgtcc ggccccacca accccgtcac ataaccggcg tgaatggtac aatcgagcgg
     8101 cgcgacggcg ggcttgtcca tgcccggaaa gcgtttttcc aggccgttca gcgtgataac
     8161 ggcatcattc atgtcctgcc tcgtcaccga attgtaccgt cactggcatt ccctggcgta
     8221 acgcatcatc ggcgtcggtc accacaatac gcaggcgata gacgaggtcg gtacgcagat
     8281 ccggcgtttc gacggttttc ggggtaaatt cagcagtcgg cgaaacgaaa ccaatctgcc
     8341 cgtgatacgg cttgtccggg cgaccatcgg tataaagcag cactttgcgc cccggctggg
     8401 cctggtcaag attacgttca tcaacataag cgcgcaccca caccggacgc gttagtgaaa
     8461 cggtaaacac cgtgccacct tcattgagga ccgtgcctgg ctccaccgcg cgcgttaaca
     8521 gcgtgccatc agacggggct atcaacgttg agtcctgtaa attcaactcc gcctgcgcca
     8581 gttgcgcctg cgcctgttcg aggctggctt tcgcctgagc gatgtcctgt tcacggttac
     8641 cggaacggta ctgacgcaat ttatcctgtg ctgatttcag cgttgcctgc gcctggtcgc
     8701 gcgaggagcg ggcattttcc aggtcatttg ccgaaatagt gcggcttttc cacaaccctt
     8761 gctggcggtt atagaagttc tgcgcatagt cataggcggc ttgcgcctgt ttcaccgctg
     8821 cggcggcctg agcgatttct tcatcgcgat acccggcaag catcaggtca tactgcgcct
     8881 gtgccaccga aacacccgct ttcgcctgca tcagggcaat ctcatacggc ttgtgatcca
     8941 gttcgcccag cacctggccc gctttgatag catcaccttc gtccaccgcc agcgattcaa
     9001 cgcgcccccc aacacggaaa ctaagattta ccgtacgaat atccacgttg ccatacagcg
     9061 tcaggccgtt atcctggcgg ctttgatacc accagtagcc tccggcaacc acggcggcaa
     9121 gtaccactac cgccaatccg atcacgacag gttttttcat cactacaaac tcctttgcga
     9181 taatccttgc aaaatcaggt cgatatgaca ggtcaccgtc tggttgatca gttcggtctt
     9241 ttcttcatcg aacgcggtcc agccggtacg taacagaatt gtttctttgc caagacggaa
     9301 cgccagaatc tcaccaatca acgcatgggt atgaaggatc atgcgggtgt cattggcgtc
     9361 gcagccggtc caggcggcaa tcaggcgtgt caggtggctg tgtagcggac taatcacctg
     9421 ttcgtgcacc aggtggtagg ctgccgtggg agagagctgc tcacgggaga taaacttgct
     9481 gaggttgacg gtgtcatcct gggtgagcag cttaatcatg ttcctgcagg cgcgaaggat
     9541 cagttcacgg atggcagccc gatcaggctg tggttgcgcg aacaagcgtt cggcttcctc
     9601 ggcatgcgga cggaactgct cgccaataaa atcggcaatc cactgggcgc aggcgaggta
     9661 caaatcttct ttcgaaccga agtagtaggt gatggcagcg atattctgcc cggcctgggc
     9721 ggctatctcg cgagtggtgg cgttcattcc atattcacca aactgcgcca gtgcggcagc
     9781 aatcagctgt tttttcgcct gttcaccctt gattgtcatg gcaggattat tcatcgcaca
     9841 gtccattctt aatcaaatga ttgattaaga ttatgactcc ataggggagt tgtccagtat
     9901 ggctaagaat tttagcaacg ccagtcacag ggataattta tgcgctgcgt cacaaaaact
     9961 gctacactcc gctccctcat gacattgtgg tttttgtcat tttccttttc agtatctccc
    10021 tgaaaactac accggtaacg gtcggggcgg ttcggagtag ttatgtcttt cgattctttg
    10081 ggtttaagcc ctgatatcct gcgcgccgtt gccgagcagg gttaccgtga acccacccct
    10141 attcagcagc aggcgatccc tgcggtgctg gaaggccgcg acctgatggc tagcgcccag
    10201 accggcaccg gcaaaacagc gggctttacg ctgccgctgt tgcaacacct gatcactcgc
    10261 cagccgcacg ccaaagggcg tcgtccggta cgtgcgctca ttcttacccc gacccgtgaa
    10321 ctggcggcgc agattggcga aaacgtccgt gattacagca aatacctgaa cattcgttcg
    10381 ctggtggtgt ttggtggtgt gagtattaac ccgcagatga tgaaactgcg tggcggcgtt
    10441 gatgtgctgg tggcaacccc gggacgtttg ctggacctgg aacatcagaa tgcagtgaag
    10501 ctggatcagg ttgaaatcct cgtcctcgat gaagctgacc gcatgctcga catgggcttt
    10561 atccacgata tccgtcgcgt gttaacaaaa ctacctgcga agcgccagaa cctgttattc
    10621 tccgcgacct tctctgacga tattaaagcc ctggcggaaa aactgttgca caacccgctg
    10681 gaaatcgaag tggcacgccg caataccgcg tctgatcagg tgacccagca cgttcacttt
    10741 gtcgataaga aacgcaaacg cgaattgctg tcgcacatga ttgggaaagg gaactggcag
    10801 caggtgctgg tgtttacccg taccaaacac ggcgctaacc atctggctga acagctcaat
    10861 aaagatggca tccgtagtgc ggcgatccac ggcaataaat cgcaaggtgc gcgtactcgt
    10921 gcgctggctg attttaaatc gggcgatatt cgtgtactgg tggcaactga catcgctgcg
    10981 cgcggcctgg atattgaaga gctgccgcac gtcgtcaact atgaactgcc aaacgtacct
    11041 gaagattatg tccaccgtat cgggcgtacc ggtcgtgcgg ctgctaccgg tgaagcgttg
    11101 tcgctggtgt gtgttgatga acacaaactg ctgcgtgata tcgaaaaact gctgaaaaaa
    11161 gagatcccgc gcattgcgat tccgggctat gagccggacc cgtcaatcaa agccgaaccg
    11221 atccagaacg gtcgccagca acgtggcggc ggcggtcgtg ggcaaggtgg tggtcgcggt
    11281 caacagcaac cacgccgtgg ggaaggtggc gcaaaatctg caagcgcgaa acctgcagaa
    11341 aaaccgtctc gccgcctcgg cgatgccaaa ccggcaggcg aacaacaacg tcgccgccgt
    11401 ccgcgtaaac ctgccgctgc gcagtaatct tttatgccgg gctatgcccg gcatcaggct
    11461 gatgaacaaa cgcaaaactg cctgatgcgc tacgcttatc aggcctacgt gaactctgca
    11521 atatattgaa tttgcatgct tttgtaggcc ggataaggcg tttacgccgc atccggcatt
    11581 tcacaacaag cacttgtcag caatttgaga acacgggaaa aaatttatct gttttaccgc
    11641 ccataagcca ccgagacgtt acttctctat agccaattgt tcgcgcaact ccattaaaag
    11701 gtagcccagt cgattcttgc ccttaccatg accaccgtct ccccagtaag catcgttttc
    11761 cgtatgctca accagttttg cgggcgcggt tgccagcaag agcgcacgca gttctgcatg
    11821 ctgttcgaat ttagcgcgaa gtgcttttcg catcacctgt tctttgaccg actcccagtt
    11881 tttacgcaga ggcttagaac gatcgcgccc catgcgtgcg gcgaccatag gggaagaaac
    11941 ccgacggatc tcttcgcggt atttttcatc aaggaatttt tgtgcctgaa aatagtgttc
    12001 tgaggtgggc caggttttcc cgtcaacctt gatgggccag gcggcaaagt tagaaaaatc
    12061 accgtagtca tcgctggtgc tgtagaaatt tatgatggtg tcttgcatga cgtgttggat
    12121 cctttgtgct cgaacgggca ttaaaccgca ttatgttggt ggttattgcg agccgctttc
    12181 cagaaacaga aaaaccatta cccctgaaaa ccgaaaaatg ccacaatatt ggctgtttat
    12241 acagtatttc aggttttctc atggcattaa ccgccgcgct taaagcgcaa attgccgcct
    12301 ggtataaggc gcttcaggaa cagatccccg actttattcc ccgtgcgccg cagcggcaga
    12361 tgattgcgga cgtcgccaaa acgctggccg gagaagaagg gcgacatctg gcgattgaag
    12421 cccccaccgg cgttgggaaa acgctctctt atttgattcc cggcatcgcc attgcccgcg
    12481 aagagcaaaa aacgctggtg gtgagtaccg ccaacgtggc attgcaggat cagatttaca
    12541 gcaaagattt accgctgctg aaaaagatca ttcccgatct taaattcact gccgcttttg
    12601 ggcgtgggcg ctacgtttgt ccgcgtaatc tgacggcgct cgccagtact gaacccacgc
    12661 aacaggatct gctggcgttt cttgacgacg aactgacgcc gaacaatcag gaagagcaaa
    12721 aacgttgtgc gaagctgaag ggcgatctcg atacttataa atgggatggt ctgcgcgatc
    12781 atactgatat cgctatagat gacgatctct ggcgtcgttt aagtaccgac aaagccagct
    12841 gcctcaaccg caattgttac tactatcgtg aatgcccgtt ttttgtcgct cgtcgggaga
    12901 ttcaggaagc ggaagtggtg gtggcaaacc atgcgctggt gatggcggcg atggaaagcg
    12961 aagcggtatt gcctgacccg aaaaatttac tgctggtgct ggacgaaggc catcacctgc
    13021 cggatgtggc gcgggatgcg cttgagatga gcgccgaaat caccgcgccg tggtatcggc
    13081 tacagctgga cttgttcacg aaactggtcg ctacctgcat ggagcagttt cgcccgaaga
    13141 ccatcccacc gctggcgatc cctgaacgtt tgaatgcgca ttgtgaagag ttgtatgagc
    13201 ttatcgcctc gttaaacaac attctcaatc tctacatgcc tgccgggcag gaggcagagc
    13261 accgttttgc gatgggcgaa ctgccagatg aagtgctgga gatctgccag cggctggcaa
    13321 aactcaccga gatgctgcgt ggcctggcgg agttatttct taacgattta agtgagaaaa
    13381 ccggcagcca tgacattgta cgtctgcatc ggttgatttt gcagatgaac cgcgcgttgg
    13441 ggatgttcga ggcgcaaagc aaactctggc ggctggcttc gctggcgcaa tcttccggtg
    13501 caccggtgac caaatgggcg acgcgggaag agcgcgaagg gcagctacac ctctggtttc
    13561 actgcgtggg aatacgtgtc agcgatcagc tggaaaggct gctgtggcgc agtattccgc
    13621 acattattgt cacctccgca accttgcgtt cgctgaacag tttttcgcgt ttgcaggaga
    13681 tgagtggtct gaaagagaaa gcgggcgacc gttttgtggc gctggattcc ccctttaacc
    13741 actgcgaaca gggcaaaatt gttattcccc ggatgcgcgt tgagccttcc atcgacaacg
    13801 aagagcagca tattgccgaa atggcggcct ttttccgtaa gcaggtggag agcaaaaaac
    13861 atctcggtat gttggtactg tttgccagcg gacgggcgat gcagcgcttt ctcgactatg
    13921 tgacggattt acgtctgatg ttgctggttc agggcgatca gccgcgttac cgtttagttg
    13981 aactgcaccg caaacgcgtc gccaacggtg agcgcagcgt gctggtgggc ttacagtcat
    14041 ttgccgaagg gcttgatttg aaaggtgatc tgctcagcca ggtgcatatc cacaaaatcg
    14101 cttttccgcc catcgacagc ccggtggtga tcaccgaagg ggaatggctg aaaagcctca
    14161 accgctatcc gtttgaggtg caaagcctgc cgagcgcctc gtttaacctg attcagcagg
    14221 ttgggcgact gattcgaagc cacggttgct ggggcgaagt ggttatctac gacaaacgct
    14281 tgctgaccaa aaattatggc aagcgactac tggatgcatt accggtattt ccgatagagc
    14341 aaccggaagt ccctgaaggt atagttaaaa agaaagaaaa aacgaaatcc ccacgccgtc
    14401 ggcggcgtta atgatgtgag tcaggtaagg agtcgtaaat ggactatcgc aaaatcatta
    14461 aagagatcgg gcgcgggaaa aaccacgcgc gcgatttaga ccgggatact gcgcgcggtc
    14521 tgtatgctca tatgctcaat ggtgaagtcc ctgaccttga gttgggcggc gtattgattg
    14581 cgctgcgtat caaaggagaa ggggaagcag agatgctcgg cttttacgaa gccatgcaaa
    14641 atcacaccat caagctgacg ccgccagcag gcaagccgat gccgattgtc atccccagtt
    14701 acaacggcgc gcgtaaacag gccaacctga cgccgttgtt ggcgattctc ctgcacaaac
    14761 tcggttttcc tgtggtggtt cacggggtta gcgaagatcc aacccgcgtg ctgactgaaa
    14821 ccatttttga attgatgggt attacgccaa cgttgcacgg cgggcaggcg caggcgaagc
    14881 tcgacgaaca tcaaccggtg tttatgccag tcggcgcgtt ttgcccgccg ctggaaaaac
    14941 aactggcgat gcgctggcgg atgggcgtgc gtaacagtgc acataccctg gcgaaactgg
    15001 cgacgccatt tgccgaaggt gaggcgctgc gtctttccag cgtttcgcat ccggaataca
    15061 ttggacgcgt cgcgaagttc tttagcgata tcggcgggcg ggcgctacta atgcatggta
    15121 ctgaaggtga agtgtatgct aatccgcagc gctgcccgca gatcaatctc attgaccgtg
    15181 aagggatgcg ggtgctgtat gaaaaacagg acactgctgg tagcgagtta ctgccacaag
    15241 caaaagatcc ggaaaccacg gcgcagtgga ttgagcgttg ccttgctggc agcgaaccga
    15301 ttcccgaatc gctgaaaatc cagatggctt gctgcctggt ggctacgggt gaagcggcaa
    15361 ctatcagcga cggcctggcg cgcgttaatc aggcatttta attcttttct cagccggatg
    15421 agccatgtca tccggctttt accccaccgc aatatgaaat tcctgcatct ttattgacct
    15481 tcccacgccc ggcgtgcagc ataaaaatac aacaaacaca taacataaac aggagttaac
    15541 catggaaagt ggtcatcgct ttgatgctca gacgctgcac agttttattc aggctgtatt
    15601 tcgtcagatg ggtagcgagg aacaagaagc gaaattagtt gccgatcatt taatcgcggc
    15661 aaacctggca gggcatgatt cacatggtat tggcatgatc ccaagctatg tacgctcctg
    15721 gagtcagggg cacctgcaaa ttaaccatca tgccaaaacc gttaaagagg cgggggcggc
    15781 ggtcacgctc gatggcgatc gcgcatttgg tcaggtcgcg gcacatgaag cgatggcgct
    15841 ggggattgag aaagcgcatc agcacggtat tgccgccgtg gcgctacata actcgcatca
    15901 tatcggccgt atcggttact gggcggagca gtgtgcagcg gcggggtttg tctctatcca
    15961 ctttgttagc gtggtcggta ttccaatggt cgcgccgttc cacggtcgcg acagccgctt
    16021 tggcaccaat ccgttctgtg tggttttccc tcgtaaagat aatttcccgc tgttgcttga
    16081 ttacgccacc agcgccattg catttggcaa aacccgcgtc gcctggcata aaggcgtccc
    16141 cgtgccgcca ggttgcctga ttgacgttaa cggcgtgccg acgaccaatc cggcggtaat
    16201 gcaggagtcg ccgttgggtt cgctgttgac ctttgccgaa cataaaggct acgcccttgc
    16261 agcgatgtgt gaaattcttg gcggggcgct ttccggcggt aaaacgacgc atcaggaaac
    16321 gttacaaacc agtcccgatg ccattcttaa ctgcatgacc actatcatca tcaacccgga
    16381 actcttcggc gcgccggatt gtaacgcgca gaccgaagcc tttgccgagt gggtgaaagc
    16441 ctcgccgcat gatgatgata agccgatttt gctaccgggc gagtgggaag tgaacacgcg
    16501 tcgcgaacgg cagaagcagg ggattccact ggatgcggga agctggcagg ccatttgtga
    16561 tgcagcgcgg cagattggta tgccggaaga gacgttgcag gctttctgtc agcagttagc
    16621 cagctaaaaa aaagcccgtc cagtggcgga cgggcaaaca agggtaacat aggatcaatg
    16681 agggttagag catatgcgtc tgtcggcaaa cagacaggga aatacttgtg ctggacgtag
    16741 cgtaaacgcc tgatccgtcc aacggttcgg attttgtagg cctgataaga cgcggtagcg
    16801 tcgcatcagg catctgttgc cggatgcggc gtaaacgcct tatccgtcct acgaattact
    16861 tataaattac cgcagtaccg cttaatttat tgttgttggt ggcggaagtg atgctgtatc
    16921 cactggcacc ggctgccgcg gctttctcag ccagtttcgc ttccagggca tcgagggtgg
    16981 atgcgccatc ggcagaaacc acgccgattt tattcatgtt ctgtgcctgg gatgccgtta
    17041 ccggttccgc cgcgaacacg ccaaatgaca gagttgaaag agccatagca gcaacaacag
    17101 tattgatagt tttcataatt aatctctcgc aggtgatttt tgtataagtg acgttgtttc
    17161 gtcgatgtga tgagtatcac gtttttttac gagagataaa atcgaagaga attgaccgcc
    17221 ttgttcaaat aaattgattg atatctaacc tactgataaa ccatttattt gttgtactta
    17281 tgaacttgtt ttataccgcg tggcagtcac agcagcgtta aaggcacgga atgacacgca
    17341 aaatacaaat tatactcgct atgcatctcg ccagttgtag ttaacgtaac tggctgtctt
    17401 tcgaacctct gcgattatat cctgtataag ctggtttttg taaatctttc tcctgctgac
    17461 aatgaataca taagcgcacg ccaggaatgg cttcccgacg ggcctgcggg atgggggcac
    17521 cgcactcttc acattcatcc aggctttcgc cgcgcggaat ttcaccccga gcgcgggcaa
    17581 tcgcatcttc aattgtactg ttgatctgtt cgttgacggc gtcatcgtta gcccaaccgg
    17641 atgccatatc gacctcccca tatcaatact tgtacagtta agtgtagcta atccagggac
    17701 gaactcgggc agttcaagca tcagatctcc gaccattccc gcagcagatt atgataaaga
    17761 ttaagcagcg acaggatctc ttcactttcg ccgtagcggc ttttcagcga ctgaatattg
    17821 ttgtccagtt caaacagcat ggcgcgcttt ttatcatcgc ggatcatcga ctggatccac
    17881 ataaatgatg ccactcgtac gccgcgggtt acgggtgtca cgcaatgcag gctgctggag
    17941 ggatacaaca cgagatcgcc tgccgggagt tttacccgat gttgtccgaa ggtgtcatta
    18001 acgaccagtt cgccgccgtc gtagctttgt ggatcgctta aaaacagcgt ggcagaaagg
    18061 tcagtacgca tccagccgtt ttgtggatgg ctgcgtactg cgccatccac atggaaacca
    18121 taggtttcat tgttctgata gcgattaaac agcggcgtgg aaagggtacg cggcaaggcc
    18181 gcggcaaaga ataaagcatg ttggttaacc gcgttcagca cctcattttg cagggcggcg
    18241 tataacgtgc tgcgggtgtc gacctgttga ttgttcttaa cttgcgcacc ttgtgcgccg
    18301 gtggtgacgc gtccatccac ccattcggct tgttccagtt gttcgcgaaa acgagcgacg
    18361 tcctgtggcg ataacacgcc gggaatgtgg tacatcatac aatttctcca aaaagtgggg
    18421 cctgcgcccc acatctgaat cagaaatgca tattggctgt gagcaagaag gttcttggct
    18481 cgcccgggtg ataacggtag ccgctcttgt tgattgaggc gacgtaatcg gtatcaaaca
    18541 ggttgtaaac gtttagctgg aagtcgagat tgcgattaac tcgatacccc agtttggcat
    18601 cggcgaccca gtaaccttcg gtaaacgctg gcgttcccac cgcgccgtct gaacctttat
    18661 gcatactgcc gatatagcgt gcgcccgcgc caacagagat atcgtcggtt gcctgatatt
    18721 ggctccataa ggtgaaggcg tgctccgggg tatacggcag cgatgaggaa ccatcctggg
    18781 caacatcttt gccgtttttg atggttgctt tttgctgggt atagccgcca atcacctgcc
    18841 acgcgggagt gatattcccg gccacggata tctcatagcc ttcgacgcgt ttcttaccgt
    18901 attgcgagta agttccgtca tcattttgct caacttcatt ttcgatatca gtgcggaaca
    18961 gcgcggcggt gagcaacaga cgtttatcca gaacctgcca tttggtgcca atctcgctgg
    19021 tgttggcttt ttgcggttta aaatcggtgc ggttggcact gttaccgctg ccagactgcg
    19081 caagggcgaa gttgttgccg cccggaggct gctgggaaac ggcatagtta atatagacat
    19141 tgccgttttc cgtcaggtga tacagcgccc cggctttcca gttcatcaga ttgcccgact
    19201 tggcggtgtc gacggtggtg accggagaac cttttgccac accagttggg caggtgatgg
    19261 caccgcgtcc gctgccgccg caggcggtgg cactgtcata ttcagtatga taattatcca
    19321 gacggatccc gccgttcagc tcaaaatcac gggtgatttg cagcgtatca aaggcgtaaa
    19381 ttgcgaaggt atccgtctga ccattggcgt ttgcgccgtt gcgcgtcagg ccgccgggat
    19441 gaatgctgct gtcaggatga taaatattta ccgcgggtaa cgtcaccgga ttaacgccgt
    19501 agttagtctg cgtttcacgg gtaaattcca cgccggtact gacatcatga ccgatagaac
    19561 cggtatagaa cgtcgaggtc aggttggtct ggttggtgag aattttatta ctcacatctt
    19621 tggtattcgc cgtgcgtgac caggtccagc tattcacatc gctggtgggc tgagtaatat
    19681 tcgacgcccc gcccataatc gccgtcatca ggtaatcctg ctttacgcgc gaccaacggg
    19741 tagtattgcg aatggtggtg ttatcgttga tgtcgtgctc aaaacgcatg gtggcggtgt
    19801 cggtggtcga atcgtcgtaa tcggaatccg tgccgtaaaa gttatgagta tcaacttttc
    19861 cggaatgatt cagggccgcc gttcccgcag atggggcaga atagcccggc aaaccgatgg
    19921 tcggaatgcc gccgtctggc gtgttgtgct gggtgacatg cagataatta agatacaaac
    19981 gattcgctgt accaaggcca aaagcgacag aaggggcgac gccgtaacgc tcatttttga
    20041 ctttgtcgcg tccggcatcg tgcgtttttt cgcccattac attcaggcgc accgcggtgg
    20101 tatcaccaat gacctgattg acgtccagcg tgccgcggcg gaaccaggcg ctgccaatac
    20161 tggcggaggc gtcaatgccg gaatcattgc gcggctgctt gctgatcata ttgatcgagc
    20221 ctgtcggtgc gctgcgcccg tagtcggtgc cggacggccc tttaatcact tcgacctgct
    20281 cggtattgaa ggtgtcgcgc gagacgctgc cgatatcgcg aatgccatca atataaatac
    20341 tgttagaggt atcggcacca cgcatataaa tggcgtcgcc agtggtggag ttaccgttct
    20401 cacccgcaaa aaacgcaccc acgccgggga cgtttttgag cgcgtcggta aggttggttg
    20461 cgccctgatc tttaatcact tgttcagaaa ttaccgtcat cgtgcgggta gtatccgcta
    20521 ccggacgcga gaatttcgga tcggcagatt gttgtggcgc ataaagcgaa ggcgttgatg
    20581 cttcgacaac cagcgtgtca tccgcgttag tttgcccttc ggcggcgagt gcctgagcca
    20641 caggcgtgat gccaatacaa agaccggcaa agaacgtgag cgaatgaaat tgtctggcag
    20701 ggaaattgcg attgttttcc attttgcagg tgactttttc ttatatgttg aaattttcac
    20761 tgccacgaga aagcctctct gcggatgcga tgccactgtt aatcccgtga tagtgctcgt
    20821 gaaagtgata ataattttga taagcattat cacttggagc gattttctat cacccattgc
    20881 gcgaaaaaga aatacattta tttacattga gttcatattt gatgtttttt gattacaaaa
    20941 cagacgaaaa ctgcatccag aggcgaatgc agttacgttg gtggggttat ttgtagatgg
    21001 ttgcagtacc gaacatctgg tcatttccgc ctgcggaatt aatgacataa cctttcgcgc
    21061 cttgttcgcg cgctttttct gccagtttat cctccagatc gcttaggttt gatgcgccag
    21121 ttgccgaaac ggtaccggcg ggccgtagct gaccgctgtc caggttactc atcggttgcg
    21181 cggcataagc cgtgagagag attccgctca ggacggtggc aatcagtagt gtgaggcact
    21241 ttttcataat gacatcctca taaatacaac gggtagtgcc tgataagtgt aggtcgcctg
    21301 cgcgatgcaa atgacgcaaa aaattgacag agatgtgctt attttttgaa cgatatattt
    21361 ttacaaaata agacaaatca atgacatgca taatgctgat ttttatgatg aattgccata
    21421 aaccatagcc atgttaaggt tttggggaat gataaacgca gccagatatt taccctgtcg
    21481 cgttatgcgg gtatcttacg ccgctgctta aaggagaatg ctatgtccgc ccagaaaccg
    21541 gggttgcatc cgcgcaaccg tcatcacagc cgctacgatc tcgccacgct ttgtcaggtc
    21601 aatcctgaac tcaggcaatt cctcacgctt acacccgccg gggagcaaag cgtagacttt
    21661 gccaatccgc tggcggtgaa ggcgctcaat aaggcgttgc tggcccattt ttacgccgta
    21721 gcgaactggg atatccccga cggttttctc tgcccaccag taccgggccg ggcggattat
    21781 attcatcacc ttgccgattt actggcagaa gcaagcggaa caattccagc gaatgccagc
    21841 attctggata tcggcgttgg tgcgaactgt atttatccgc tgattggcgt acatgaatat
    21901 ggctggcgtt ttaccggtag tgaaaccagc agccaggcgt taagcagtgc gcaggcgatt
    21961 atcagttcta atccggggct taaccgcgcc attcgtctgc gtcggcaaaa agagagtggg
    22021 gcgattttta acggcatcat ccataaaaac gagcaatacg acgcgacctt gtgtaacccg
    22081 ccattccacg attccgccgc tgcggcacgg gcaggtagtg agcgtaaacg ccgtaacctg
    22141 gggctgaaca aagacgatgc actgaacttt ggcggccagc aacaggagtt gtggtgtgaa
    22201 ggcggtgaag tcacctttat caaaaagatg attgaagaga gcaaaggctt cgcgaagcag
    22261 gtgatgtggt ttacatcact ggtatctcgt ggtgaaaact taccgccgtt gtatcgtgcc
    22321 ctgacggacg tgggcgcggt gaaggtggtt aaaaaagaga tggcccaggg gcaaaagcag
    22381 agtcgcttta ttgcctggac ctttatgaac gacgagcagc gccgccgttt tgtcaatcgc
    22441 cagcgttaaa gcgttggttc ccccggcggt aacggttcag ccggggtcgc gcccggagca
    22501 ggcagcacct gataagtctg cactggcgcg cgaacgcccg ccaggtcgaa atgttttttc
    22561 acctggctgt cgagggcaaa gcgtaccgtc cactgtttga gtggcagcgt ggtgaacgaa
    22621 acacgcagtg taaacgcggt attgcttaag ccgacaatcc cggcaaaatt cggttcacca
    22681 ataatcagcc cgcgaatttc ttcgttttcc attaattccg ctaccgcatc tttcagtgcc
    22741 tgattggctt tatcagcatc ttcatggcga tcaacatcat aatttgccac caccgaacca
    22801 atgccgcgga caaagttagc aaaggtggtt atcgaagacc acggaatgat gtgatacgcc
    22861 ccggtatcct gtcgtacgcc cacggagcga atcgacatcc gttccactgt gccggtcaac
    22921 ggcccgatag tcaccaaatc tccagtgttc atgccgtttt caaactgaat aaataccccg
    22981 gtgataatat ctttcaccag cgtttgcgaa ccaaacgaga tagccagacc taatgccccg
    23041 gcacctgcca gcaatggcgc gatattgacg ccgatttccg acaacacaat catgatggtg
    23101 atggtactga taatcaccgc cagcgcgtta cgaaacagcg taagcagggt acgcgtgcgg
    23161 gcgctgggta gcgggcggcc atgaatatcc gaagccagcc ggttttcgat caaactggcg
    23221 agcaccgtcc agccaaccgc cgagaagaaa agaatgagtg cgatacggat caggatatct
    23281 acggttttct gccccgcgcc gttttgcagc cagttccaga aatcgaacaa tccccatgcg
    23341 ctcaacagca acattaccgc cacgcagact gtcagaatac gcgccgtttt cagcgccgcc
    23401 gacagccagc cattcaaccg tttttgcagc tccggatagt tacgctgagt atgtggcgag
    23461 agagtgatgg ttttcgccag ccagcgggaa aacataccgg aaacaaacgc tgcgatacca
    23521 ataatcgcca ggctgcgcac cgttgcaccc atcataaatt tcaggctgtt gcccggatcg
    23581 aacaacgaaa agaaaaacag cacgataaaa taggcgcttg ccagccagtg ccacaccagc
    23641 gcaaaggcgc ggataaacag gctgaaaaag gccagcgaat gctccgcgaa gttgagcaaa
    23701 tgctgggtaa tctctttttt attacgaaag atcaggtaca acgcccagac ggtcatgcac
    23761 agcataatga tgacgttcgc cagcgcacct atctgtacat tcacctgatt agagataatc
    23821 ggcacggcca caatcaggcc ataacctatc aaactgctta accagctcag gcgacgactc
    23881 cagtaacggg cgctctcgtc ctgaatcgtg aacgggcgca gctccgccac gtttgggcaa
    23941 aaaatcaggc gtagtacggc tttgaaaaat tcaatgaggg caaaggcgtt gagaaacaaa
    24001 ctttgttgga aagcgatggt gcgactgcct gcattcaggt tgtcgcttaa tacctggccg
    24061 acaaataatg tcagggccag taacagcagg tcgataataa acgccccgat aatcatcgcc
    24121 ggaagctgca accagttgct gcgctcacga tttttttgcc gcgcccactg acccattttg
    24181 cgatacagcg gcagtgcgca caggcgaatc agccagtaaa aaccaaacac taataccgct
    24241 aacattgaaa aatgggtcag cgcattgctg aaggtttgtg gattaaacgg cttatgcggg
    24301 gagccggtga tattgcgata aagttgcccg aagcgggcgg aaagggcttc accataatgg
    24361 cggctgactt cggtgacctt ttgcagcacg gtttgctctt cgaccagcgt cggcggcact
    24421 atttttggta ccggttcagc agggggcgta gcggcaacgg tgcgcaactg gtcgatcaac
    24481 tctttacgcg aggtgtcatt atccagcaca tccgccagtg cgccataggc cgcttttttt
    24541 tgttcgatat ccggttccgg ggccggttca gtcgttgagt ccgttgtcgt tgtggttgta
    24601 acgccgggta tggataccgc gtgggcaggt gcgcccagca ggcagaagag gatgaacagg
    24661 atccaccgca tgactcctcc agtgagaaaa tagagcaaaa agataagtat agatgctgga
    24721 ggaggggcga ttttaaatga gaggaatctg gtgtgcctcc ctttcgggtg aaagggagga
    24781 agggatatta agcaggttgc tgacaacgtg cgggcttttt tgtcggatgc ggcgtgaacg
    24841 ccttatccgt cctacaagtt catgcaattt taataagttg ccagatatcc tgtaggcctg
    24901 ataagcgtag cgcatcaggc aatgtgtctt attaagagac gtgctgcaaa aattcctgca
    24961 agcgctggct cggcgggttc ttgatcaaca cctgcggatt gccatcttcc gcaatccggc
    25021 ctttgtcgat aaagatcagc cgcgaagcta ctttctcggc aaaaccgatt tcgtgggtca
    25081 cgatcaccat cgtcatccct tcttcagcca gatcctgcat aaccttcagc acttcatggc
    25141 gcagttccgg gtcaagagcg gaagtcggtt catcaaacag catcattttc ggcttcaccg
    25201 ccagcgcgcg ggcaatcgcc acacgctgct gttgaccacc agaaagttcg gaagggtagt
    25261 gatgtgcacg ttctgccaga ccgactttcg ccagcagctc acgtgccagt ttttccgcct
    25321 cttctttgtt cgcgccacgc acgcgtagcg ggccaaacat gacgttttcc agcgccgtca
    25381 gatgcgggaa gaggtaaaac tgctggaaca ccatacctgc ttcctggcga atcaggcgct
    25441 cgtcaacttt cggatcgtta accttcaggc catcgacaat cagatcgccg gaggtgattt
    25501 cttccagttt gttgatgcag cgcagcaggg tcgatttacc ggaaccggac ggcccgataa
    25561 tcaccacgac ttcgccctgg gcaatgttca aatcgatatt gtgcagcacc tgggttgggc
    25621 caaagtgctt ggagacgttt ttaaattcaa tcacaggatt ttcatccttc tttccagacg
    25681 acgcagaata aagctcagca ccagggtaat aatcagatag aacaccgcca cggcgctcca
    25741 gatctcaagg gcgcggaagt taccggcaat aatttcttgc ccctgacggg tcagttccgc
    25801 cacgccgatc acaataaaca gcgaggtgtc tttaatgctg atgatccact ggttacccag
    25861 cggcggcagc atacgacgca gtgccagcgg taaaatgacg tagcgaatgg tttcccaacg
    25921 tgaaagaccg agcgccagtc ctgcttcacg aaaacctttg tggatagaca gcaccgcacc
    25981 acgcgtgatt tccgcaatat acgcgccgga gttgatcatg atggtgacca ccgccgcagt
    26041 aaatgggtcg atgcgtaagt cgttaaacgc catcggcagg gcgaaataaa taaacatcac
    26101 ctggacgacg ataggtgtgc cgcggatcac ttcaataaag accagcgcga cgtggttggc
    26161 tatccaacct ccgaaggtgc gtgcaaaacc tgccagcaat ccgattacca gaccgcctgc
    26221 cagaccgagg accgaaatcc acagggtcat tttggcacct tcaatcagaa gcggaatggc
    26281 aggccagatg gcactccagt caaactgcat atgttgttcc tgttaccgtg gtgtaaataa
    26341 tcaaattcag ggtaattaat ggccccggag cgggttgcgc ccctcaccct aatcctctcc
    26401 ccatagggga gagggaactg ccagtgcgtt ttacaggtgt agcgttatta tttcggttca
    26461 gtaccgaacc attttttgta gatttcgttg taagttccgt tctcgcgcag ggttttcaac
    26521 gcgccgttga ctttgtcacg cagctcgtcg ctacctttcg ggaacgcaat accgtattgc
    26581 tgcgcttcca gagagtcacc taccgctttg aactgaccgt taccggcggt tttgatgaag
    26641 tacagaatgt ttggcgtatc gtgcagaacg gcgtctgcgc ggttggtgcc cagttccata
    26701 taggcgttat cgatgttcgg gaactgacgc agatctttag ttttgatgtt tgctttcgcg
    26761 taatcaacgg agccagtacc gctcttcaca gcaaccactt tcccgtcgag atctttcacg
    26821 cttttcacat cgttattgtt agctttcacc atcactaaca ggccgctttt gtagtagccg
    26881 tcagagaaat cgatcgcttt tttacgctcg tcggtgatgg taatgcccgc cagcgccaga
    26941 tcgacgtttt tggtttgcag tgccggaatg atcccactga aatccatcgg cttcagttcg
    27001 taatccagct tcagctcttt agcgatggca gcccacagat caacgtcaaa gcccacatat
    27061 ttatcgccct gtttaaattc aaacggaacg aaggcggtat ccgtcgcgac aactaatttt
    27121 ttatccgcgg catgagaaga aaccgcaaaa gccagggtca gtgcagccag tgaaactttt
    27181 aatacagact tcatagcatt tccttttttc tatccacggg acgatcccct gcgtgacatt
    27241 cacatatatg aaaaaatcgt gccagttttg caactccttg atttttcgag atgcggcaaa
    27301 aacgtgatgc acgatttata gggcaatacc ctgaagatgc accattctgg ggcaccaatc
    27361 tggtgcgcta aaattgtgca ctcaacacag tgattattta gcgtaaaacc tgatgaaaaa
    27421 acaatcttta tgtaacgatt gtgtgatgat gtggatacaa aaaatttact taatcagctg
    27481 gagatagcag atggatgcac taaataagtg cgttgaggtg ggctgcaaaa caaaacggcc
    27541 tcctgtcagg aagccgcttt tatcgggtac taaagttctg caccatcagc gatggattta
    27601 ttcgatgtta gactcgataa accacaggaa tttatccagg tcgcgagacg cggcggtcag
    27661 gatatctgcg gtgtcgtcat ctttcgcttc gccaatcgct ttgcgtacgt cattagcgac
    27721 gattgcgtaa cggtcagcca gttctttcag gtgatcctga acgttgtgga tgtccagcgg
    27781 gtaacttttc agcggggttt tgctgttgat aacttgagtg gtccccagag ctacaccgcc
    27841 cagctgcact gcacgttctg ccatggtatc cagatgatcg atcagtgcgg tgcggaagcc
    27901 atccagcatt tcatgtacgg caatgaagtt agcgccgcgc atgttccagt gcgcttgttt
    27961 ggtaatcaaa gaaagatcaa taaactggat aacctggcga ttcagcaact ctactgttgc
    28021 ttttttctcg ctgtcggaga catcgttgcg ggtataaagc agattggtcg cttttgattt
    28081 aactaattta gcggtactca taatttcata tcctcttgat gttatgtccc agtaattaac
    28141 gagactaagt atagcaccgg ctatgtgttc cgctattctg gctgttccta tcacactaat
    28201 agtggtaaca agcgtgaaaa acaaaactaa taaa
//
LOCUS       DAPHKZ010000053        27993 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.053, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000053 DAPHKZ010000000
VERSION     DAPHKZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27993
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.053"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(40..630)
                     /gene="paaY"
                     /locus_tag="RH288_002405"
     CDS             complement(40..630)
                     /gene="paaY"
                     /locus_tag="RH288_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="HDV4031452.1"
                     /translation="MPIYQIDGLTPVVPEESFVHPTAVLIGDVILGKGVYVGPNASLR
                     GDFGRIVVKDGANIQDNCVMHGFPEQDTVVGEDGHIGHSAILHGCIIRRNALVGMNAV
                     VMDGAVIGENSIVGASAFVKAKAEMPANYLIVGSPAKAIRKLSEQELAWKKQGTHEYQ
                     VLVTRCKQTLHQVEPLREIEPGRKRLVFDDNLRPKQ"
     gene            complement(612..1562)
                     /gene="paaX"
                     /locus_tag="RH288_002406"
     CDS             complement(612..1562)
                     /gene="paaX"
                     /locus_tag="RH288_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation operon negative
                     regulatory protein PaaX"
                     /protein_id="HDV4031453.1"
                     /translation="MSKLDTFIQHAVNAVPVSGTSLISSLYGDSLSHRGGEIWLGSLA
                     ALLEGLGFGERFVRTALFRLNKEGWLDVSRIGRRSFYSLSDKGLRLTRRAESKIYRAE
                     QPAWDGKWLLLLSEGLDKSTLADVKKQLIWQGFGALAPSLMASPSQKLADVQTLLHEA
                     GVADNVICFEAQIPLALSRAALRARVEECWHLTEQNAMYETFIQSFRPLVPLLKEAAD
                     ELTPERAFHIQLLLIHFYRRVVLKDPLLPEELLPAHWAGHTARQLCINIYQRVAPAAL
                     AFVSEKGETSVGELPAPGSLYFQRFGGLNIEQEALCQFIR"
     gene            complement(1662..2975)
                     /gene="paaF"
                     /locus_tag="RH288_002407"
     CDS             complement(1662..2975)
                     /gene="paaF"
                     /locus_tag="RH288_002407"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HDV4031454.1"
                     /translation="MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKF
                     DAAGVHPDDFRELSDLRKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTV
                     VGYTQNDIDNWANIVARSLRAAGGSPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
                     MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPW
                     TQAMRKEIERRLGITALDIYGLSEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPHDG
                     TPLADGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRRMDRISGRSDDMLII
                     RGVNVFPSQLEEEIVKFEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQV
                     CHQLRHRIKSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA"
     gene            complement(3002..4207)
                     /gene="paaJ"
                     /locus_tag="RH288_002408"
                     /gene_synonym="paaE"
                     /gene_synonym="ydbW"
     CDS             complement(3002..4207)
                     /gene="paaJ"
                     /locus_tag="RH288_002408"
                     /gene_synonym="paaE"
                     /gene_synonym="ydbW"
                     /EC_number="2.3.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase"
                     /protein_id="HDV4031455.1"
                     /translation="MREAFICDGIRTPIGRYGGALSSVRADDLAAIPLRELLVRNPRL
                     DAECIDDVILGCANQAGEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAAR
                     AIKAGDGDLLIAGGVESMSRAPFVMGKAASAFSRQAEMFDTTIGWRFVNPLMAQQFGT
                     DSMPETAENVAELLKISREDQDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVT
                     EIQHDEHLRPETTLEQLRGLKAPFRANGVITAGNASGVNDGAAALIIASEQMAAAQGL
                     TPRARIVAMATAGVEPRLMGLGPVPATRRVLERAGLSIHDMDVIELNEAFAAQALGVL
                     RELGLPDDAPHVNPNGGAIALGHPLGMSGARLALAASHELHRRNGRYALCTMCIGVGQ
                     GIAMILERV"
     gene            complement(4207..4629)
                     /gene="paaI"
                     /locus_tag="RH288_002409"
     CDS             complement(4207..4629)
                     /gene="paaI"
                     /locus_tag="RH288_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyphenylacetyl-CoA thioesterase PaaI"
                     /protein_id="HDV4031456.1"
                     /translation="MSHKAWQNAHAMYENDACAKALGIDIISMDEGFAVVTMTVTAQM
                     LNGHQSCHGGQLFSLADTAFAYACNSQGLAAVASACTIDFLRPGFAGDTLTATAQVRH
                     QGKQTGVYDIEIVNQQQKTVALFRGKSHRIGGTITGEA"
     gene            complement(4619..6046)
                     /gene="paaC"
                     /locus_tag="RH288_002410"
     CDS             complement(4619..6046)
                     /gene="paaC"
                     /locus_tag="RH288_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase PaaC"
                     /protein_id="HDV4031457.1"
                     /translation="MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRA
                     IDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKAL
                     FAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLA
                     TAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDA
                     ALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGK
                     KSGLGVYDWRAEREAVVGLEAVSDSFSPMKVEKKSDGVTEIDDVLLIETQGETAQALA
                     IRLARPVVVIDKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWR
                     TVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQH
                     HYGEERYRPCSLLRQRALLESGYES"
     gene            complement(6048..6836)
                     /gene="paaB"
                     /locus_tag="RH288_002411"
     CDS             complement(6048..6836)
                     /gene="paaB"
                     /locus_tag="RH288_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
                     isomerase"
                     /protein_id="HDV4031458.1"
                     /translation="MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVER
                     DDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPV
                     ICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA
                     MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINS
                     AETNTLDTQLDLERDYQRLAGRSADYREGVSAFLAKRSPQFTGK"
     gene            complement(6836..7603)
                     /locus_tag="RH288_002412"
     CDS             complement(6836..7603)
                     /locus_tag="RH288_002412"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dehydroadipyl-CoA hydratase"
                     /protein_id="HDV4031459.1"
                     /translation="MSELIVSRQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATD
                     TSISVCVITGNARFFAAGADLNEMAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGY
                     ALGAGCELALLCDVVVAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSG
                     ESITAQQAQQAGLVSDVFPSDLTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQ
                     AGLAQERQLFTLLAATEDRHEGISAFLQKRTPDFKGR"
     gene            complement(7600..8670)
                     /gene="paaK"
                     /locus_tag="RH288_002413"
     CDS             complement(7600..8670)
                     /gene="paaK"
                     /locus_tag="RH288_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase/reductase subunit
                     PaaK"
                     /protein_id="HDV4031460.1"
                     /translation="MTTFHSLTVAKVESETRDAVTITFAVPQPLQEAYRFRPGQHLTL
                     KASFDGEELRRCYSICRSYLPGEISVAVKAIEGGRFSRYAREHIRQGMTLEVMVPQGH
                     FGYQPQAERQGRYLAIAAGSGITPMLAIIATTLQTEPESQFTLIYGNRTSQSMMFRQA
                     LADLKDKYPQRLQLLCIFSQETLDSDLLHGRIDGEKLQSLGASLINFRLYDEAFICGP
                     AAMMDDAETALKALGMPDKTIHLERFNTPGTRVKRSVNVQSDGQKVTVRQDGRDREIV
                     LNADDESILDAALRQGADLPYACKGGVCATCKCKVLRGKVAMETNYSLEPDELAAGYV
                     LSCQALPLTSDVVVDFDAKGMA"
     gene            complement(8678..9175)
                     /gene="paaD"
                     /locus_tag="RH288_002414"
     CDS             complement(8678..9175)
                     /gene="paaD"
                     /locus_tag="RH288_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate degradation protein PaaD"
                     /protein_id="HDV4031461.1"
                     /translation="MQRLATIAPPQVHEIWALLSQIPDPEIPVLTITDLGMVRNVTQM
                     GEGWVIGFTPTYSGCPATEHLIGAIREAMTTNGFTPVQVVLQLDPAWTTDWMTPDARE
                     RLREYGISPPAGHSCHAHLPPEVRCPRCASVHTTLISEFGSTACKALYRCDSCREPFD
                     YFKCI"
     gene            complement(9190..9936)
                     /gene="paaC"
                     /locus_tag="RH288_002415"
     CDS             complement(9190..9936)
                     /gene="paaC"
                     /locus_tag="RH288_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaC"
                     /protein_id="HDV4031462.1"
                     /translation="MNQLTAYTLRLGDNCLVLSQRLGEWCGHAPELEIDLALANIGLD
                     LLGQARNFLSYAAELAGEGDEDTLAFTRDERQFSNLLLVEQPNGNFADTIARQYFIDA
                     WHVALFTRLMESRDPQLAAISAKAIKEARYHLRFSRGWLERLGNGTDVSGQKMQQAIN
                     KLWRFTAELFDADEIDIALSEEGIAVDPRTLRAAWEAEVFAGINEATLNVPQEQAYRT
                     GGKKGLHTEHLGPMLAEMQYLQRVLPGQQW"
     gene            complement(9945..10232)
                     /gene="paaB"
                     /locus_tag="RH288_002416"
     CDS             complement(9945..10232)
                     /gene="paaB"
                     /locus_tag="RH288_002416"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit B"
                     /protein_id="HDV4031463.1"
                     /translation="MSNVYWPLYEVFVRGKQGLSHRHVGSLHAADERMALENARDAYT
                     RRSEGCSIWVVKASEIVASQPEERGEFFDPAESKVYRHPTFYTIPDGIEHM"
     gene            complement(10244..11173)
                     /gene="paaA"
                     /locus_tag="RH288_002417"
     CDS             complement(10244..11173)
                     /gene="paaA"
                     /locus_tag="RH288_002417"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit A"
                     /protein_id="HDV4031464.1"
                     /translation="MTQEERFEQRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIV
                     GMLPEGNWITRAPTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDIYQKMLDGRM
                     KYSSIFNYPTLSWADIGVIGWLVDGAAIVNQVALCRTSYGPYARAMVKICKEESFHQR
                     QGFEACMALAQGSEAQKQMLQDAINRFWWPALMMFGPNDDNSPNSARSLTWKIKRFTN
                     DELRQRFVDNTVPQVEMLGMTVPDPDLHFDTESGHYRFGEIDWQEFNEVINGRGICNQ
                     ERLDAKRKAWEEGTWVREAALAHAQKQHARKVA"
     gene            11458..13503
                     /gene="paaZ"
                     /locus_tag="RH288_002418"
     CDS             11458..13503
                     /gene="paaZ"
                     /locus_tag="RH288_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation bifunctional
                     protein PaaZ"
                     /protein_id="HDV4031465.1"
                     /translation="MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAA
                     RQFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEG
                     GIGTLFTYASLGSRELPDDTLWPEDELIPLSKEGGFAARHLLTSKSGVAVHINAFNFP
                     CWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDL
                     LDHLDSQDVVTFTGSAATGQMLRVQPNIVAKSIPFTMEADSLNCCVLGEDVTPDQPEF
                     ALFIREVVREMTTKAGQKCTAIRRIIVPQALVNAVSDALVARLQKVVVGDPAQEGVKM
                     GALVNAEQRADVQEKVNILLAAGCEIRLGGQADLSAAGAFFPPTLLYCPQPDETPAVH
                     ATEAFGPVATLMPAQNQRHALQLACAGGGSLAGTLVTADPQIARQFIADAARTHGRIQ
                     ILNEESAKESTGHGSPLPQLVHGGPGRAGGGEELGGLRAVKHYMQRTAVQGSPTMLAA
                     ISKQWVRGAKVEEDRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSGDHFYAH
                     MDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLESLRFIEPVKPGDTI
                     QVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD"
     gene            13751..16024
                     /gene="tynA"
                     /locus_tag="RH288_002419"
     CDS             13751..16024
                     /gene="tynA"
                     /locus_tag="RH288_002419"
                     /EC_number="1.4.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415904.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primary-amine oxidase"
                     /protein_id="HDV4031466.1"
                     /translation="MGSPSLYSARKTTLALAVALSFAWQAPVFAHGGEAHMVPMDKTL
                     KEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVPVVMKDNKAWVSD
                     TFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLP
                     PDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVL
                     LDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVI
                     SYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVK
                     PMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSL
                     GGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP
                     MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENG
                     TIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDV
                     DGENNSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKE
                     NRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEG
                     KYPNRSTHDTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKP
                     WNFFDETPTLGALKKDK"
     gene            complement(16082..17581)
                     /gene="feaB"
                     /locus_tag="RH288_002420"
                     /gene_synonym="maoB"
                     /gene_synonym="padA"
     CDS             complement(16082..17581)
                     /gene="feaB"
                     /locus_tag="RH288_002420"
                     /gene_synonym="maoB"
                     /gene_synonym="padA"
                     /EC_number="1.2.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415903.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetaldehyde dehydrogenase"
                     /protein_id="HDV4031467.1"
                     /translation="MTEPHVAVLSQVQQFLDRQHGLYIDGRPGPAQSEKRLAIFDPAT
                     GQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEELA
                     QLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIAGKTLDLSIPLPQGARYQAWTR
                     KEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGI
                     PDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLELGGK
                     NPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSLQ
                     VGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVN
                     PDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRL
                     QAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCVRY"
     gene            17817..18722
                     /gene="feaR"
                     /locus_tag="RH288_002421"
     CDS             17817..18722
                     /gene="feaR"
                     /locus_tag="RH288_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator FeaR"
                     /protein_id="HDV4031468.1"
                     /translation="MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGL
                     KLSTVTTSGVNLSRTWQEVKGSDDAWFYTVFQLSGQAIMEQDERQVQIGAGDITLLDA
                     SRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMN
                     NPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEW
                     IAGETGMSVRSLYRMFADKGLVVAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFS
                     DQSHFSTVFKQRFGMTPGEYRRKFR"
     gene            complement(18894..19220)
                     /locus_tag="RH288_002422"
     CDS             complement(18894..19220)
                     /locus_tag="RH288_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HDV4031469.1"
                     /translation="MKKTLLLCAFLVGLVSSNVMALTLDEARTQGRVGETFYGYLVAL
                     KTDAETEKLVADINAERKASYQQLAKQNNVSVDDIAKLAGQKLVARAKPGEYVQGING
                     KWVRKF"
     gene            complement(19228..19413)
                     /locus_tag="RH288_002423"
     CDS             complement(19228..19413)
                     /locus_tag="RH288_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HDV4031470.1"
                     /translation="MKILLAALTSSFMLVGCTPRIEVAAPKEPITINMNVKIEHEIII
                     KADKDVEELLETRSDLF"
     gene            complement(19410..22049)
                     /locus_tag="RH288_002424"
     CDS             complement(19410..22049)
                     /locus_tag="RH288_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HDV4031471.1"
                     /translation="MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRI
                     ALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLNVGTVELDSACLAKL
                     PQTEQSPAAPKTLAQWQAMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
                     KVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFAMPLVPDGLPVSGHATATLNLPQ
                     EPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLS
                     GRLGVKVDNWQAGLENALVSGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPLQLTG
                     EAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKV
                     TQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATW
                     DVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPIVWVRDAQHPSFSGAL
                     SLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLR
                     GNAWWPKQSLTVFQPLVPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAW
                     MPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTE
                     EEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAF
                     SGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEIS
                     RSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQA
                     WLEQNARLPGNDCPQGKECEEKQ"
     gene            22257..23246
                     /gene="ldhA"
                     /locus_tag="RH288_002425"
     CDS             22257..23246
                     /gene="ldhA"
                     /locus_tag="RH288_002425"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDV4031472.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAML
                     RILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEA
                     AFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEKGETCPNELV"
     gene            23357..23779
                     /gene="hslJ"
                     /locus_tag="RH288_002426"
     CDS             23357..23779
                     /gene="hslJ"
                     /locus_tag="RH288_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HDV4031473.1"
                     /translation="MKKVAAFVALSLLMAGCVSNDKIAVTPEQLQHHRFVLESVNGKP
                     VTSDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELD
                     NTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN"
     gene            complement(23776..24042)
                     /locus_tag="RH288_002427"
     CDS             complement(23776..24042)
                     /locus_tag="RH288_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HDV4031474.1"
                     /translation="MRAAFWVGCAALLLSACSSEPVQQATAAHVAPGLKASMSSSGEA
                     NCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            24316..27840
                     /gene="nifJ"
                     /locus_tag="RH288_002428"
     CDS             24316..27840
                     /gene="nifJ"
                     /locus_tag="RH288_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDV4031475.1"
                     /translation="MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISQIATLKSR
                     VPFIHFFDGFRTSHEINKIVPLADDTILDLMPQVEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYNAVYDHVEQAMNDFSAATGRQYQPFEYYGHPQAERVIILMGSAI
                     GTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARF
                     TVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAF
                     FHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHS
                     ANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     IWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPAELLT
                     ALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKLPLALDSRPPSEALEETLLHEQRFRRLNSQQPEVAEQL
                     WKDAAADLQKRYDFLAQMAGKAEKSNTD"
BASE COUNT         6804 a         7538 c         6897 g         6754 t
ORIGIN      
        1 ctgcttaata attaaaggga caaaataatt ttacatctgt tactgtttcg gtcgcagatt
       61 gtcatcaaat accaggcgtt tcctgccagg ttcaatttcc cgcaatggct cgacttgatg
      121 taacgtctgc ttacagcgtg tcaccagcac ctggtactca tgcgtaccct gctttttcca
      181 tgccaactcc tgctcactga gtttacgaat cgctttcgcc gggctgccga caatcaggta
      241 attagctggc atttctgctt tggctttcac aaatgcggat gcaccaacaa tgctgttctc
      301 gccaatcacc gcaccgtcca tcactaccgc gttcattccc actaatgcat tgcggcggat
      361 aatgcagccg tgaaggatag cgctatgacc aatatgtcca tcttctccta caacagtatc
      421 ctgctcggga aaaccgtgca taacgcaatt atcctgaatg ttcgcgccat ctttcaccac
      481 gatacgacca aaatcgccac gcaggctggc atttggccca acgtaaacgc ccttgccgag
      541 aataacatcg ccgatcaata ccgctgtcgg atggacaaaa ctctcttctg gcacaaccgg
      601 agtcagaccg tctatctgat aaattggcat aacgcctcct gttcaatatt caagccgcca
      661 aaacgttgaa aatacaggct tcccggcgca ggcagttcac cgaccgaggt ttcacctttt
      721 tcactaacga acgctaaagc agcaggcgct acgcgctgat aaatgttgat acacagctga
      781 cgcgccgtat gccctgccca gtgtgccgga agcaactcct ccggcaacaa tgggtcttta
      841 aggacgacac ggcgataaaa atggatcagt aaaagctgaa tatgaaatgc ccgctccggg
      901 gttaactcgt ctgccgcctc ttttaaaagc ggcaccagcg ggcggaatga ctgaataaag
      961 gtttcgtaca tggcattttg ttcagttaaa tgccagcact cttctactct ggcacgcagt
     1021 gctgcgcgag aaagcgccag tggtatttgc gcttcaaaac aaatcacgtt atccgccaca
     1081 cccgcttcat gcaaaagtgt ctgtacatcg gccagttttt gcgacggcga tgccatcagg
     1141 ctgggtgcca gtgcgccaaa accttgccag atcaactgct ttttgacatc agccagcgtt
     1201 gatttatcta aaccttccga gagcaacagg agccatttac catcccatgc aggttgctct
     1261 gcgcgataaa ttttactttc tgcccgtcgc gtcaggcgca agcctttatc actgaggcta
     1321 tagaaactgc gtcgcccgat gcgggaaaca tccagccagc cttctttatt aagacgaaac
     1381 aaagcggtgc gcacgaaacg ctcaccaaat cccagccctt ccagcaaagc agccagacta
     1441 cccaaccaga tttcaccacc acgatgggaa agcgaatcac catacagaga ggagatcaaa
     1501 gatgtgccac tgaccggaac agcgtttaca gcatgttgga taaaagtatc aagtttactc
     1561 attcgcttca gtctgttgtt attgttgtga tttatgaatc atagcacagg tcgtatcgac
     1621 ttctggccct ggcgctttcc ccaccagggc cagacgatac gtcaggcacc aacaatattg
     1681 cgcagatcaa acacccgaca cgccttgcct tctgaacgcg ggatactgcc acagttaacg
     1741 atcatcacat cggtagagat ccccaccatc gacttaatcc gatggcgcag ctggtggcat
     1801 acctggcaac gctgctcatg cgtcaatgtc aggctacttt ctttcaactc cactttcaca
     1861 gaaagtgaat caagatgccc ccggcggttc acctccagtt ggtaatgcgg cgataaatgt
     1921 tcgaatttga caatctcttc ttccagttgt gacggaaaga catttacacc gcgaataatc
     1981 aacatgtcat cgctgcgtcc gctgatgcga tccatgcggc gcatagtccg cgccgttcct
     2041 ggtaacagtc gggttaaatc acgcgtgcgg taacgaatga ccggcaatgc ttctttggtc
     2101 agcgtggtga ataacagttc gccatgttca ccatcggcaa gcggtgtgcc gtcatgagga
     2161 ttaacaattt caggatagaa atgatcttcc caaatggttg ggccgtcggt agtttccaga
     2221 cactccatcg ccacccccgg ccccatcact tctgacaggc cataaatatc cagtgcggtg
     2281 atccccaggc gacgctcaat ctctttacgc atggcctgtg tccacggctc agcaccaaat
     2341 actccaaccc gcagcgagca accgctggca tcaccgccca actgccgctc cagctcttca
     2401 atcaggttaa ggcaataaga tggcgtaacc atgatcatat ctggttgaaa atcacggatc
     2461 agttgcgctt gtttttccgt ctgcccgcca gacatcggga tcaccgtagc gcccagacgt
     2521 tcggcaccat agtgcgcacc cagcccacca gtaaacaggc cgtaaccata ggcaacatga
     2581 attttgtctt tgggcgagcc ccctgccgca cgcaaagaac gcgctacaat attggcccag
     2641 ttatcaatat cgttttgcgt atagccgaca actgtcggtt tacctgtggt tcccgaagaa
     2701 gcatgaatgc gcaccacttg ttccattggc acggcaaagg tgtcaaaggg atagttgtcg
     2761 cgcagatcct gtttggtggt acagggaaat ttacgcaggt ctgaaagttc cctgaaatca
     2821 tcaggatgta cgcctgctgc gtcgaatttg cgccgataca tcggcacatt ttcatacgcg
     2881 tgtttgagcg tccatttcag acgctgtgtt tgcaacgcct gtaactcatc aacagacgcg
     2941 gtttcaatcg ggtcaagctt tgtattggtt atcattgtag ggtactcgca ggttgatatg
     3001 ctcaaacacg ctccagaatc atggcgatgc cctgaccgac accgatgcac atggtgcaca
     3061 atgcgtaacg accgttacgc cgatgcagct catggctggc agccagtgcc aggcgggcac
     3121 cactcattcc caacggatgg cctaaggcga tagcgcctcc gttggggtta acatgtgggg
     3181 catcatcagg cagccccaat tcgcgtagta cacccaacgc ctgggccgcg aacgcttcgt
     3241 tcagttcaat cacgtccata tcgtgaatac tcagccctgc gcgttccagc acccggcgag
     3301 ttgcaggcac cggaccaagc cccatcaggc gcggttccac cccggcggtt gccatggcta
     3361 cgatacgcgc ccgcggtgtc agtccttgcg ctgctgccat ctgttcactg gcaataatca
     3421 acgcagcggc tccgtcattc accccggaag cattgcctgc ggtaatcacc ccattggcac
     3481 gaaatggtgc ttttaaccca cgtaactgtt ccagcgtcgt ttccgggcgc agatgctcat
     3541 catgttgtat ttctgttaca acacctttct tgtttttcaa cacaaccgga acaatctcct
     3601 cagccagaat gcctgaggat tgcgcttttg ccgtacgttg ctgactgcgt agcgcaaaac
     3661 tatcttgatc ttctcgtgag atttttaaca gttcagctac attctctgcc gtttccggca
     3721 tgctgtcagt tccaaattgc tgagccatga gcgggttcac aaatcgccag ccaatagtgg
     3781 tatcgaacat ctcagcctga cgagaaaatg cactggctgc cttgcccata acaaacggtg
     3841 cccgtgacat tgactccacg ccaccggcga tcagcaaatc gccatcgccc gctttaatcg
     3901 cccgtgcggc aaaccccagt gcgtccagcc cggaaccaca caagcggtta atggttgtgc
     3961 cggaaacact ctgcggcagc cccgccagta aagtcgccat ccgggctacg ttacggttat
     4021 cttctcccgc ctgattagca cagccgagga tcacatcatc gatacactcc gcatcgagac
     4081 gcgggtttcg caccagcagt tcccgcaaag ggatagcagc cagatcatca gcccgaacac
     4141 ttgataatgc cccgccgtag cgaccaattg gcgtacgaat tccgtcacaa ataaaggctt
     4201 cacgcatcag gcttctcctg taatggtgcc gccgatgcgg tgagatttac cgcgaaacag
     4261 cgcaaccgtt ttttgttgtt ggttaacaat ttcgatgtcg taaacaccgg tttgcttgcc
     4321 ctgatgacgt acctgcgcag tagcagttaa ggtgtctccg gcaaagcctg gacgcaaaaa
     4381 atcaatcgtg caggcagaag cgacggctgc cagcccctgg ctattgcagg cgtaggcaaa
     4441 ggcagtatca gccagtgaaa atagctgccc gccgtggcaa ctttgatgac cgttaagcat
     4501 ttgtgcagtg acggtcatgg tcactacagc aaagccttca tccattgaga taatgtcgat
     4561 gccaagcgct ttggcgcagg catcgttctc atacattgca tgggcatttt gccaggcctt
     4621 atgactcata accgctctcc agaagcgccc gttggcgcag caatgaacat gggcgatagc
     4681 gttcttcgcc atagtgatgc tgtagatttt caaggagcct taatattcgc tgccagccaa
     4741 gttgcgctcc ccaggcaagt gggccatatg gataattcac cccaagacgc atggcggtat
     4801 cgatatcctg ttcagaggcc acgccttttt gaagcgcatc aagggcttca ttgatgatca
     4861 ttgctaccgt tcgccaaatc agcattcctg ggtaatctgc aatttgcagc actgttttgc
     4921 cctgctgttg caggtaataa atggccttgc gggtcgctga gtccgggttc accgctgcag
     4981 cagcaatggt caccaccttg cccgccattt tatcgatcac taccaccggg cgtgccagtc
     5041 gtattgccag cgcctgtgcc gtctcgcctt gtgtctcaat caataaaaca tcgtcaattt
     5101 ccgtgacacc gtcacttttc ttttctactt tcattgggct aaaactgtcg cttaccgctt
     5161 ccaggccaac aactgcctca cgttccgcgc gccagtcgta cacgcccagc ccacttttct
     5221 tgcccaaccg tccaccaatc accagttcct gttgcaccag cgaaggtaaa aaacgacgct
     5281 cctgccagaa agcgttaaac accgaacagg tgacagcaaa attgacgtcc tgaccaatca
     5341 gatcggttaa ttccagcggc cccatcggga aaccagcgcc atcgcgaagt gcagcgtcaa
     5401 tcacttctgg tgcagcaacc tgctcttcca gtgcccgcca ggcctcggaa taataaggac
     5461 gcgcaacacg gttaacgata aatccaggag tcgaatgaca gcgcacaggc tgcttacccc
     5521 aactcaacgt tagttcacac aactgctcaa caacttccgc cgccgttgcc agcccactga
     5581 ccacctccac caacttcatc accggtgccg ggttaaaaaa atgcagcccc gcaacacgtt
     5641 caggattttt tatctccgca gcaatcgcgg ttatagagat tgacgaagtg ttagtggtca
     5701 atagcgtttg tggcgggcaa acttccgcca gctgtgcaaa gagcgctttt ttgacttcca
     5761 gacgttcaga cgccgcttca atgaccaggt ccgcagctgc cagcgcgtga atatcggtca
     5821 ccgggatcag gcgtttcaat gtgcgttcac aggtttcagc agtcagtttt ccccgcgtca
     5881 cgcgtgaatt tagccgcgcg tgtatcccgt cgattgcgcg ggtcagcgct tcagcagaaa
     5941 tgtcatacag taaaacctgg tgtccatgac tggcagcaac ttcagcaatg cctgccccca
     6001 tggtgccgct cccaatcact gccacagttt gcacatttat catcatgcta tttccccgtg
     6061 aactgcggtg agcgtttagc caggaacgca ctgacacctt cacgataatc tgcgctccgt
     6121 ccggcaagtc gctgatagtc acgttccaga tccagttgcg tatcgagcgt attggtttca
     6181 gcgctattta tcgcttgctt gataagtcca agaccaaatg tcggttgtgt cgccagatgc
     6241 cgtgccagct gttgcgcggt atctgccagc gtttcatcat caacaacctg ccagatcatc
     6301 ccccattcgt gcgcctgttc agcactcagt tgattcccca gcagtgccag ccccatggcg
     6361 cgcgctcgtc cggcaacgcg tggcagtaac caggttccac cgcaatcggg tattaagcct
     6421 aacttactaa acgccatgac gaattttgct gaacgggcag caataacgat gtcgcccccc
     6481 agtgccagtg ttgcgcctgc ccctgccgcc acgccattga ctgcacagat caccggtttt
     6541 ggcagttttg ccaggcgacg taccagtggg ttatagaaac gttcaactga catccctaaa
     6601 tccggtgcgg ggcctgtggg atcaacgtta cgatcgttaa gatcctgacc agcacaaaat
     6661 ccgcgcccgg cacctgtaag taacaggcaa cggatagtgt cgtcgcgctc gacctgtttc
     6721 aggcactctg ccagttgtgc gtgcatctca tcattaaaac tgttcaggcg ttccgggcgg
     6781 ttgagcgtta gtgtcatcac gcccttttct acatgactga ggatgaattc catcattagc
     6841 gtcctttaaa gtcgggcgtg cgtttttgta agaaagcgga gatgccttca tgacgatctt
     6901 ctgttgccgc cagcaaggtg aataactgtc gctcctgggc aagtccggct tgcaaagcca
     6961 cttcctgcga ctggcgcagc gcttgctttg ccgcttgtaa ggccagcggc gagtgacgtg
     7021 ccattttcga tgccagctgt aaggcgtatt cgagggttaa atcgctgggg aagacgtcgc
     7081 taaccagccc ggcctgctgt gcttgctgag cggtgatact ttctccgctc agcaccattt
     7141 tgctggctaa cgatttaccg acactacgga ttaaacgttg cgttccgcct gcgccaggca
     7201 tgatgccgag agtgatttcc ggcaacccaa aacgcgcgtt ctctccggca accaccacat
     7261 cgcacaacaa tgccagttcg caacccgccc caagcgcgta accattgacg gctgcgataa
     7321 gtggtttatt aaaggcctgc aatcgcgccc atagctgcgg acgtgtatcg tttaaggtgg
     7381 ccgcgagatc tttttctgcc atttcgttga gatcggcccc agcggcaaaa aagcgtgcat
     7441 taccggtaat cacacagacc gaaatgctgg tatcggtagc cgcagcttcc agttcattta
     7501 ccagttgcat cagcagggca ttatttagcg cattacgtgc ggcgggacgg ttaagggtca
     7561 gcaacaatac tcgttgctga cggctgacga tcagttcgct catgccatcc ccttcgcgtc
     7621 aaagtcaacc accacatcgc tggtcagcgg cagtgcctgg caactcaaca cataacctgc
     7681 ggccagttca tccggttcca gactgtaatt ggtttccatc gccactttgc cacgcagcac
     7741 tttgcatttg caggtcgcac agacgccgcc tttgcaggca tagggcagat ccgccccctg
     7801 gcgcaatgcc gcatcgagaa tgctttcatc gtcggcatta agcacgattt cccgatcccg
     7861 cccatcctga cgtacagtca ctttttgtcc gtcactttgc acgttaacgc tacgtttgac
     7921 gcgcgtgcca ggcgtattaa accgctccag atgaatggtt ttatctggca ttcccagtgc
     7981 ttttaaggcg gtttccgcgt catccatcat cgccgccgga ccacaaataa atgcctcatc
     8041 ataaagacga aaattaatga gcgaggcccc aagtgactgt aatttttcac cgtcaatacg
     8101 cccgtgaagc agatcgctgt cgagggtttc ctgactgaaa atgcacaaca actgtaaacg
     8161 ctgaggatat ttgtctttca ggtctgccag tgcctggcga aacatcatgc tctggctggt
     8221 acggttaccg tagatcaggg tgaactgact ttcaggctcg gtttgtaaag tggtggcgat
     8281 aatcgccagc attggcgtaa tacctgatcc tgctgcaatt gccagatagc gcccctggcg
     8341 ttcggcctgc ggctgatagc cgaaatgccc ctgcggcacc atgacctcca gcgtcatacc
     8401 ctggcggatg tgttcgcggg catagcggga gaaacgtccg ccttcaatgg ctttcaccgc
     8461 cacactaatt tcgccaggca gatagctgcg gcaaatggag taacaacggc gtaattcttc
     8521 accatcaaag ctggctttta aggtcaaatg ttgaccgggg cgaaagcgat acgcctcctg
     8581 caaaggctgg ggcaccgcaa aggtaatggt caccgcatca cgggtttccg actcgacttt
     8641 tgccactgtt aaggaatgaa acgttgtcat ggcatcctca aatacatttg aaataatcga
     8701 aaggttcgcg gcaactatcg cagcggtaca atgctttgca ggccgtggaa ccaaattcac
     8761 tgataagtgt ggtatggacg ctggcgcagc gcgggcaacg tacttctggc ggcaaatggg
     8821 catggcaact gtgtccggcg ggcgggctaa tgccatactc tcgcagacgc tcacgggcat
     8881 cgggggtcat ccagtcggtg gtccatgccg ggtcgagttg cagcacaacc tgaacggggg
     8941 taaacccgtt ggttgtcatt gcctcacgta tcgcgccaat caaatgttcc gttgccggac
     9001 aaccggaata tgtcggcgta aagccgatca cccatccttc tcccatctgt gtcacattac
     9061 gcaccatgcc taaatcagta atggtcagca ccgggatctc cgggtccggg atctggctga
     9121 gtagcgccca tatctcatga acctgtggcg gtgcaatggt ggccagacgt tgcataccca
     9181 tctcctctgt taccattgct gaccgggcaa gacacgctgg agatactgca tttctgccag
     9241 catgggtcca aggtgttcgg tatgcagtcc ttttttaccg ccagtgcgat acgcctgctc
     9301 ttgcggtacg ttcaatgtgg cttcgttgat cccggcaaaa acttcggctt cccacgctgc
     9361 gcgtaaagtg cgtggatcaa ccgcaatacc ctcttcactc agtgcaatat caatctcgtc
     9421 ggcatcgaac agttcggcgg taaaacgcca caacttgttg atggcctgct gcatcttttg
     9481 ccctgatacg tcagtaccat tgcccagtcg ctccagccag ccacgactaa aacgcaggtg
     9541 atagcgcgct tctttaattg ctttggcaga aatcgccgcc agttgcggat cacggctttc
     9601 catcagacgg gtaaagagcg ccacatgcca tgcatcgatg aaatactggc gtgcaatggt
     9661 gtcggcaaaa ttgccgtttg gttgttcaac caacaataag ttgctgaact ggcgctcgtc
     9721 tcgggtgaag gccagggtat cttcatcgcc ttctcccgct aattcagcgg catacgataa
     9781 gaagttgcgt gcctgaccta ataaatcgag gccaatgttt gccagtgcga gatcgatttc
     9841 cagttccggt gcgtgaccgc accattcacc caaccgctgg gagagcacca ggcagttatc
     9901 gcccaggcgc aaggtgtaag ccgttaactg attcatttcc gacctcacat gtgctcaatg
     9961 ccatcaggga tggtgtaaaa cgttggatgg cgatagacct tgctttcagc cggatcaaaa
    10021 aattcaccgc gttcttccgg ttgcgaggca acaatttcac tcgccttcac cacccaaatt
    10081 gaacatcctt cgctacgacg ggtgtaagca tcacgggcat tttccagtgc catccgctca
    10141 tcggcagcat gtaaactgcc aacatggcgg tgtgataagc cctgtttgcc acgcacgaaa
    10201 acttcgtata acggccagta aacattactc attttgaatc tccttatgcg accttacggg
    10261 catgttgttt ttgtgcatgg gccagcgctg cttcccgtac ccaggtacct tcttcccagg
    10321 ctttacgttt ggcgtcgagc ctctcctgat tacaaattcc gcgaccgtta attacttcgt
    10381 taaactcctg ccagtcgatc tcaccaaagc ggtagtgacc gctttcagtg tcaaaatgca
    10441 gatccgggtc aggaacggtc ataccgagca tttcaacctg tggaacggtg ttatccacga
    10501 aacgctggcg gagttcgtcg ttggtgaaac gtttgatttt ccaggtgaga cttctggcgc
    10561 tgtttggcga gttatcatcg tttggcccga acatcattaa ggctggccac cagaaacggt
    10621 taatggcgtc ttgcaacatc tgcttttgag cttcgctgcc ctgcgccagt gccatgcagg
    10681 cttcaaaccc ctgacgctgg tgaaaactct cttctttgca gattttcacc attgctctgg
    10741 catacgggcc ataagaagtg cggcataacg ccacctgatt gacgatcgct gcgccatcca
    10801 ccagccagcc gataacaccg atatcagccc aactcaatgt cggataatta aagatggagg
    10861 aatatttcat ccgtccgtcg agcatttttt ggtagatgtc ttctctggcg cagcccagtg
    10921 tttcggcggc gctatagaga tacagaccat gaccggcttc atcctgcact ttggccaaca
    10981 gaatggcttt acgccgcaag gttggtgcgc gagtgatcca gttaccttca ggcaacatac
    11041 caacaatctc ggagtgcgca tgctgcccaa tctggcggat caatgtcttt cggtaagcat
    11101 cgggcatcca gtcctgtggc tcgatagccg tttcctgggc tatccgttgc tcaaagcgtt
    11161 cttcttgggt cacgtcatca cctttacgat tccagttttc gtgaattaat taaaaacacg
    11221 aatcacattg ttttatgaaa gttacacaat agttaagtaa aatcacaaat tttgtatgtt
    11281 tgaactgtga cggatttcgc accctatttt tataaatcat tatttatcag tgcattaatg
    11341 ttttccgcag ttgctataca gatcgcacag ttaacatttc gttaaaagat cccttgcttt
    11401 ttatgattcg cgatttaact attagcaaca gaaatgtgaa acatctggag agtagcgatg
    11461 cagcagttag ccagtttctt atccggtacc tggcagtctg gccggggccg tagccgtttg
    11521 attcaccacg ctattagcgg cgaggcgtta tgggaagtga ccagtgaagg tcttgatatg
    11581 gcggctgccc gccagtttgc cattgaaaaa ggtgcccccg cccttcgcgc tatgaccttt
    11641 atcgaacgtg cggcgatgct taaagcggtc gctaaacatc tgctgagtga aaaagagcgt
    11701 ttctatgctc tttctgcgca aacaggcgca acgcgggcag acagttgggt tgatattgaa
    11761 ggtggcattg ggacgttatt tacttacgcc agcctcggta gccgggagct gcctgacgat
    11821 acgctgtggc cggaagatga attgatcccc ttatcgaaag aaggtggatt tgccgcgcgc
    11881 catttactga cctcaaagtc aggcgtggca gtgcatatta acgcctttaa cttcccctgc
    11941 tggggaatgc tggaaaagct ggcaccaacg tggctgggcg gaatgccagc catcatcaaa
    12001 ccagctaccg cgacggccca actgactcag gcgatggtga aatcaattgt cgatagtggt
    12061 cttgttcccg aaggcgcaat tagtctgatc tgcggtagtg ctggcgactt gttggatcat
    12121 ctggacagcc aggatgtggt gactttcacg gggtcagcgg cgaccggaca gatgctgcga
    12181 gttcagccaa atatcgtcgc caaatctatc cccttcacta tggaagctga ttccctgaac
    12241 tgctgcgtac tgggcgaaga tgtcaccccg gatcaaccgg agtttgcgct gtttattcgt
    12301 gaagttgtgc gtgagatgac cacaaaagcc gggcaaaaat gtacggcaat ccggcggatt
    12361 attgtgccgc aggcattggt taatgctgtc agtgatgctc tggttgcgcg attacagaaa
    12421 gtcgtggtcg gtgatcctgc tcaggaaggc gtgaaaatgg gcgcactggt aaatgctgag
    12481 cagcgtgccg atgtgcagga aaaagtgaac atattgctgg ctgcaggatg cgagattcgc
    12541 ctcggtggtc aggcggattt atctgctgcg ggtgccttct tcccgccaac cttattgtac
    12601 tgtccgcagc cggatgaaac accggcggta catgcaacag aagcctttgg ccctgtcgca
    12661 acgctgatgc cagcacaaaa ccagcgacat gctctgcaac tggcttgtgc aggcggcggt
    12721 agccttgcgg gaacgctggt gacggctgat ccgcaaattg cgcgtcagtt tattgccgac
    12781 gcggcacgta cgcatgggcg aattcagatc ctcaatgaag agtcggcaaa agaatccacc
    12841 gggcatggct ccccactgcc acaactggta catggtgggc ctggtcgcgc aggaggcggt
    12901 gaagaattag gcggtttacg agcggtgaaa cattacatgc agcgaaccgc tgttcagggt
    12961 agtccgacga tgcttgccgc tatcagtaaa cagtgggtgc gcggtgcgaa agtcgaagaa
    13021 gatcgtattc atccgttccg caaatatttt gaggagctac aaccaggcga cagcctgttg
    13081 actccccgcc gcacaatgac agaggccgat attgttaact ttgcttgcct cagcggcgat
    13141 catttctatg cacatatgga taagattgct gctgccgaat ctattttcgg tgagcgggtg
    13201 gtgcatgggt attttgtgct ttctgcggct gcgggtctgt ttgtcgatgc cggtgtcggt
    13261 ccggtcattg ctaactacgg gctggaaagc ttgcgtttta tcgaacccgt aaagccaggc
    13321 gataccatcc aggtgcgtct cacctgtaag cgcaagacgc tgaaaaaaca gcgtagcgca
    13381 gaagaaaaac caacaggtgt ggtggaatgg gctgtagagg tattcaatca gcatcaaacc
    13441 ccggtggcgc tgtattcaat tctgacgctg gtggccaggc agcacggtga ttttgtcgat
    13501 taatcggtga atgaagggca acggcgaata gttgcccttt tatttcacta agttttgtga
    13561 cgttgtcaca ttatgcatga tgtgtacatc tattttcagg gcatccactg tatgaaaagc
    13621 tggcacacct gccaaacaac ctggcaggtg caggcaatcc cctttgcatc agtactgata
    13681 atgtgaacct gactaaaccg cccacagagc gcggttgcta acaagaacac aacatctgac
    13741 gaggttaata atgggaagcc cctctctgta ttctgcccgt aaaacaaccc tggcgttggc
    13801 agtcgcctta agtttcgcct ggcaagcgcc ggtatttgcc cacggtggtg aagcgcatat
    13861 ggtgccaatg gataaaacgc ttaaagaatt tggtgccgat gtgcagtggg acgactacgc
    13921 ccagctcttt accctgatta aagatggcgc gtacgtgaaa gtgaagcctg gtgcgcaaac
    13981 agcaattgtt aatggtcagc ctctggcact gcaagtaccg gtagtgatga aagacaataa
    14041 agcctgggtt tctgacacct ttattaacga tgttttccag tccgggctgg atcaaacctt
    14101 tcaggtagaa aagcgccctc acccacttaa tgcgctaact gcggacgaaa ttaaacaggc
    14161 cgttgaaatt gttaaagctt ccgcggactt caaacccaat acccgtttta ctgagatctc
    14221 cctgctaccg ccagataaag aagctgtctg ggcgtttgcg ctggaaaaca aaccggttga
    14281 ccagccgcgc aaagccgacg tcattatgct cgacggcaaa catatcatcg aagcggtggt
    14341 ggatctgcaa aacaacaaac tgctctcctg gcaacccatt aaagacgccc acggtatggt
    14401 gttgctggat gatttcgcca gtgtgcagaa cattattaac aacagtgaag aatttgccgc
    14461 tgccgtgaag aaacgcggta ttactgatgc gaaaaaagtg attaccacgc cgctgaccgt
    14521 aggttatttc gatggtaaag atggcctgaa acaagatgcc cggttgctca aagtcatcag
    14581 ctatcttgat gtcggtgatg gcaactactg ggcacatccc atcgaaaacc tggtggcggt
    14641 cgttgattta gaacagaaaa aaatcgttaa gattgaagaa ggtccggtag ttccggtgcc
    14701 aatgaccgca cgcccatttg atggccgtga ccgcgttgct ccggcagtta agcctatgca
    14761 aatcattgag cctgaaggta aaaattacac cattactggc gatatgattc actggcggaa
    14821 ctgggatttt cacctcagca tgaactctcg cgtcgggccg atgatctcca ccgtgactta
    14881 taacgacaat ggcaccaaac gcaaagtcat gtacgaaggt tctctcggcg gcatgattgt
    14941 gccttacggt gatcctgata ttggctggta ctttaaagcg tatctggact ctggtgacta
    15001 cggtatgggc acgctaacct caccaattgc tcgtggtaaa gatgccccgt ctaacgcagt
    15061 gctccttaat gaaaccatcg ccgactacac tggcgtgccg atggagatcc ctcgcgctat
    15121 cgcggtattt gaacgttatg ccgggccgga gtataagcat caggaaatgg gccagcccaa
    15181 cgtcagtacc gaacgccggg agttagtggt gcgctggatc agtacagtgg gtaactatga
    15241 ctacattttt gactggatct tccatgaaaa cggcactatt ggcatcgatg ccggtgctac
    15301 gggcatcgaa gcggtgaaag gtgttaaagc gaaaaccatg cacgatgaga cggcgaaaga
    15361 tgacacgcgc tacggcacgc ttatcgatca caatatcgtg ggtactacac accaacatat
    15421 ttataatttc cgcctcgatc tggatgtaga tggcgagaat aacagcctgg tggcgatgga
    15481 cccagtggta aaaccgaata ctgccggtgg cccacgcacc agtaccatgc aagttaatca
    15541 gtacaacatc ggcaatgaac aggatgccgc acagaaattt gatccgggca cgattcgtct
    15601 gttgagtaac ccgaacaaag agaaccgcat gggcaatccg gtttcctatc aaattattcc
    15661 ttatgcaggt ggtactcacc cggtagcaaa aggtgcccag ttcgcgccgg acgagtggat
    15721 ctatcatcgt ttaagcttta tggacaagca gctctgggta acgcgttatc atcctggcga
    15781 gcgtttcccg gaaggcaaat atccgaaccg ttctactcat gacaccggtc ttggacaata
    15841 cagtaaggat aacgagtcgc tggacaacac cgacgccgtt gtctggatga ccaccggcac
    15901 cacacatgtg gcccgcgccg aagagtggcc gattatgccg accgaatggg tacatactct
    15961 gctgaaacca tggaacttct ttgacgaaac gccaacgcta ggggcgctga agaaagataa
    16021 gtgattgttt cagacaaaaa aacggcacca ggtgccgttt tttacttatg agcgaaccag
    16081 attaataccg tacacacacc gacttagttt cacaccaacc gtccagccag tcggggccaa
    16141 aatcacggcc cgttcctgac tgcttcatcc caccaaacgg taagttagcg tcaattaagg
    16201 tatggctgtt tacccacacc gtccctgcct gtaagcgatc gctatattcc agagcctggg
    16261 agagattttg cgtccagaca ctggcagtta agccatattc cgtgtcgttt gccagttgta
    16321 acgcctcttc tccatccgct actcgcacca ggtttaccac cggaccaaac acctcttcac
    16381 gagttaagcg caatttagca tcgggattta ccaccagcgt tggcgcaaca taatacccct
    16441 ctccggctgg tccattcgac ccgcgaatca gctctgcttg ctgtgcctgc gcatcgtcga
    16501 ggaatgaaca cactttgtcg cagtgcgcac gagaaaccaa agggttaatc tgtgcaacag
    16561 gtgacatccc cggtcccact tgcaacgatt ttaccgcctg ctcaaatcca ctaaccagcg
    16621 tgtcaaacaa cggcgcttca atataaattc gcgaactggc ggcgcatact tgcccttgat
    16681 tcaggaagct tccggtcatc aagccttcaa taacccattg cggatcagca tcttttaata
    16741 caattgccgg gtttttaccg cccagttcca gcgttacacg cgttaagtga tcagcagcag
    16801 ttctggcaat accttttccc gtcgcggttg aaccggtaaa actgattttc gcaacatgag
    16861 gatgtgacgt cagggccgcg ccgcatacag cacctgaccc ggtgacgaca ttaaaaacgc
    16921 catcagggat accagcctcg ctggccagtt ccgccacgcg caacatcgtc agtggcgtgg
    16981 tttccgaagg cttaatcacg attgaacagc ctgctgccag tgctggcatc accttccaca
    17041 taccaatcat caacggaaag ttccatggca caattcccgc cactacgcca accggctctt
    17101 tacgcgtcca ggcctgataa cgcgccccct ggggtaaggg aatcgacaag tccagcgttt
    17161 tacccgcgat tttggtcgtt aacccggcgg tataacgcat ccagttcagc gtacagccca
    17221 cttcaaaagc acgggaaatg gcaattgact tgccttgctc cagggtttcc agttgcgcca
    17281 gctcctcact gtgctgctcc accagatcag caaaacgtag cagaatacgt tcacgctctg
    17341 cgggtaatcg cccggcccag cgacgcgaga caaaggcccg ccaggcagac atgactgcgt
    17401 tatctacatc cgcttcgttg gcatcagcag tagacgcaat ttcttgcccg gtggccggat
    17461 caaagatcgc caaccgtttt tcactttgtg cggggccagg acgaccatca atataaagac
    17521 cgtgttgacg atcgagaaac tgttggacct ggcttaatac tgctacatgc ggctctgtca
    17581 tcacttttcc ttattattta cccagtgtga tttcagtgta cgcagcgaca agaaaagtca
    17641 cttttttcgc tgtgacattc gctttgtcag ctgtgacaag ctccgcaaat cgtgacaata
    17701 accgcttatg tctctatgcc tgacaagact tatttcctat agtcaggctc attagcttcg
    17761 tttattgcaa cacaaatgca acaataaaaa tacatttcac agagcgaaaa cgtgccatga
    17821 accccgcagt ggataatgag tttcagcaat ggctttccca aatcaatcag gtatgcggaa
    17881 attttaccgg acgcctgctg actgagcgtt acacgggtgt actggacacg cattttgcca
    17941 aaggactaaa gctgagtacc gtgacaacca gcggggtgaa tttatcccgc acctggcagg
    18001 aagtaaaagg cagcgacgat gcctggtttt acaccgtttt tcagcttagt ggtcaggcaa
    18061 taatggagca ggatgagcgt caggtgcaga ttggcgctgg cgatattacg ttactcgatg
    18121 cctcacgccc ctgttcgctt tactggcagg agtcttctaa acagatttca ttacttttgc
    18181 cacgcactct gctggaacaa tattttcccc atcaaaaacc tgtctgcgca gaaagactgg
    18241 acgctgactt acccatggtg caactcagtc atcgcctgtt acaggagagc atgaataatc
    18301 cggcactttc tgaaacagaa agtgaagctg cgctacaggc gatggtgtgt ctgctgcgcc
    18361 cggtacttca tcagcgggaa tctgttcaac ctcgtcgtga acgtcagttt caaaaagtgg
    18421 ttacgttgat agacgataat attcgcgaag agatattacg cccggagtgg atagccggag
    18481 agacaggtat gtcagtacgt agtttgtacc gaatgtttgc cgataaaggt ttggtagtcg
    18541 cgcaatatat tcgtaaccgt cgtctcgatt tttgtgcaga tgcgattcgc catgccgcag
    18601 atgatgaaaa actggcaggc atcggctttc attggggttt ttctgaccag agtcattttt
    18661 caacggtatt taagcaacgc tttgggatga cgccaggcga gtatcgacgt aaattccgct
    18721 aactaattgg cgttgcatgt actgcaacgc caattagtta aaacagatat ttgactatgc
    18781 atttttcagg gcaaaaggca atttgacagg agtttttgaa tattcacctt gtttcaggaa
    18841 aatagatcaa tcgccttctc ctgtagcgtt atcccgatat tgcggttttg ctattaaaat
    18901 tttcgcaccc atttaccgtt tatcccttgt acatattccc ccggtttggc ccgagctacg
    18961 agcttttgcc cggcgagttt cgcgatatca tctaccgaca cattattttg ctttgccagt
    19021 tgttggtaac tcgctttacg ttcggcatta atgtcggcta ctaatttctc tgtttcagca
    19081 tccgttttca gcgcaaccag ataaccgtaa aatgtttcac ctacccgccc ctgagttctg
    19141 gcttcatcca gagtcaatgc cattacattg ctgcttacca gcccaacaag aaacgcacaa
    19201 agaagtaatg ttttcttcat catcacctca gaaaagatcg ctacgagttt caagcagctc
    19261 ttcgacatct ttgtctgcct tgatgatgat ctcatgctca attttaacgt tcatattgat
    19321 agtgatcggt tccttaggtg cagcgacttc aatgcgaggc gtacagccaa ccagcataaa
    19381 agatgacgtc aacgcagcca gtaaaatttt cattgttttt cctcacactc ttttccttgc
    19441 ggacagtcat ttcccggcag acgtgcgttc tgctccagcc atgcctggag attatcgcca
    19501 aagcgtaaac tgcgccacag cgtaaaaata ttctcttcat gatggtaatt aaggtttacc
    19561 gtaccgcttt taccatcaac gcgactggta cctgtaatgt tggcctgcat ggttaataaa
    19621 ccgagattat ctaaattaat ttttgtcgat gaacggctaa tttccatata gcgcaaccag
    19681 ttaattgctg aacccgcagt catattgtct tttaccaccg catccgcagt gtctttatcc
    19741 agtcgcaatg tcatcggccc gctattcgcc agccagccat ctttcacaat ccatttttca
    19801 ttgttcagcc ataacggcag tgcaccacta aatgccccgg acatggcgaa ttgtttcgga
    19861 ttgacggcgc taaccagttc gctggatgag agattattca gccgcaacag cgccgggtca
    19921 tgttgcggca tacgtaattg tttcatcagt acgttaccgc ctaacacatc gacgctaaca
    19981 tcagtcaaca gcaagggttc ttcttcagtc cacggataac gcccttgcaa atcagccgta
    20041 atatttttcg ctgtcaccag attaatcact tcggcaattc gcaacgtaac ggggccgcga
    20101 gtccccagat gccaggctcc atcggcaaaa cggaaaggca ggacaaaatc gacaccgtta
    20161 acctgattat ctggcatcca ggcactaccg cctttcaaca cgccgtgtcc tcccgcgcgg
    20221 aatccttgtt caggcgcagc agaaaatgca acctgagcat acagttcacc atcgcgtaag
    20281 ttcatcttcc agtcgggtgg caccagcggc tggaatacgg tcagtgattg tttaggccac
    20341 caggcgttac cgcgcagacg aataccgtcc cagcgaccat ttacccgaac cgggccaatc
    20401 tcaccagcat gtaaatcgcc tttaaagagg aaataggtag gatcgcgccc atcgacgcta
    20461 aattttaagg ttgatggcgg taacacactg ccgccagtga acagcgtttg cccggcgtcc
    20521 agtgacagcg cgccgctaaa ggagggatgc tgtgcgtcac gtacccagac gatgggcttg
    20581 tcgagaatta atcgcggctt ttctaccgtc atcgtaccgt attgtaactg gtcgaaaccg
    20641 gtggagagat cggtcagcgt aatcgtgctg tcatgccact caccttttcc tgcgacatcc
    20701 caggtggcat tcatcggtgt aaaactccct tttccccagt agcgccactg ccagcggcca
    20761 gcgtcaggga gaaaatcatt cgccagccca tccatatgca gcacgaaatc gcccagttca
    20821 ttttcatgcg cctgcaagat ggcctgcaaa cgtccgtcaa caccacgttg ggtgactttt
    20881 acacccgcta aaggccagcg gatttcatcg atgtccagcg aatcgatgac tcttcccttt
    20941 gaacgaagta acgcgcctgg ctcaaaggtc agcgttgggt cagacagact tccacttagc
    21001 tgcgcaggta aacgggcata taaaatgagg tccgcctgtt tcgcttcacc ggtcagctgc
    21061 agaggcagct gactgttatc catgcttaat tttcctgggc caaaattaag caccgcgttg
    21121 cccttacccg cttgcccctg ggtcagcaca ctcagtcgtc cgctgaccag agcgttctca
    21181 agccctgcct gccagttgtc gactttgaca cccagtcggc cactcaaagg aaaacctgca
    21241 tacggccagc tccagcgacc atcgcttacg gtcaattgtt gacgagtaat ttgccacggc
    21301 aaatcgagca acggatcgcc gttatcccgt gccagcacga tcaattgccc gctattttcc
    21361 tgccagtcca gctcggcatc caccagtgac ggttcctgcg gcaagtttaa cgtcgcagta
    21421 gcatgcccac ttacaggaag tccatccggc acgagcggca tagcaaattc ccccaccagt
    21481 tttaccggcg gctgattttc aaacgcgacg acatccagtt cgctgactgt aagttgttgc
    21541 cctttcagct ggccttgaaa tttaactttt tcgccctgat aacgcagttg ctggatatca
    21601 gaggttaatg cgagagagag ttttccctgc cattcctgcc agggagaaaa aatcagttta
    21661 tcgatattga tccaggtgtt aggcagcatg gcctgccact gcgcgagtgt ttttggagcg
    21721 gctggcgatt gctccgtctg cggcaatttc gccagacaag cagaatcaag ttctaccgtg
    21781 ccgacgttca ataaccagcg gctgggatgt gaaaggctgg cgttggtgat atgcgcaagc
    21841 tgacaatctc ccaccagata acggagatcg ggaatgatta aacctttacg cgtaatgcgt
    21901 gggctttcat ctaatgcaat acgtgtcccg agcggtagcc agatgcccgc cagcgtggga
    21961 acccacagcc cgagcgtcat cagcagcgtc aacggcacaa gaataatcag taataacagc
    22021 gcgagaacgg ctttatattt acccagcatg ggtagttaat atcctgattt agcgaaaaat
    22081 taagcattca atacgggtat tgtggcatgt ttaaccgttc agttgaaggt tgcgcctaca
    22141 ctaagcatag ttgttgatga atttttcaat atcgccatag ctttcaatta aatttgaaat
    22201 tttgtaaaat atttttagta gcttaaatgt gattcaacat cactggagaa agtcttatga
    22261 aactcgccgt ttatagcaca aaacagtacg acaagaagta cctgcaacag gtgaacgagt
    22321 cctttggctt tgagctggaa ttttttgact ttctgctgac ggaaaaaacc gctaaaactg
    22381 ccaatggctg cgaagcggta tgtattttcg taaacgatga cggcagccgc ccggtgctgg
    22441 aagagctgaa aaagcacggc gttaaatata tcgccctgcg ctgtgccggt ttcaataacg
    22501 tcgaccttga cgcggcaaaa gaactggggc tgaaagtagt ccgtgttcca gcctatgatc
    22561 cagaggccgt tgctgaacac gccatcggta tgatgatgac gctgaaccgc cgtattcacc
    22621 gcgcgtatca gcgtacccgt gatgctaact tctctctgga aggtctgacc ggctttacta
    22681 tgtatggcaa aacggcaggc gttatcggta ccggtaaaat cggtgtggcg atgctgcgca
    22741 ttctgaaagg ttttggtatg cgtctgctgg cgttcgatcc gtatccaagt gcagcggcgc
    22801 tggaactcgg tgtggagtat gtcgatctgc caaccctgtt ctctgaatca gacgttatct
    22861 ctctgcactg cccgctgaca ccggaaaact atcatctgtt gaacgaagcc gccttcgaac
    22921 agatgaaaaa tggcgtgatg atcgtcaata ccagtcgcgg tgcattgatt gattctcagg
    22981 cagcaattga agcgctgaaa aatcagaaaa ttggttcgtt gggtatggac gtgtatgaga
    23041 acgaacgcga tctattcttt gaagataaat ccaacgacgt gatccaggat gacgtattcc
    23101 gtcgcctgtc tgcctgccac aacgtgctgt ttaccgggca ccaggcattc ctgacagcag
    23161 aagctctgac cagtatttct cagactacgc tgcaaaactt aagcaatctg gaaaaaggcg
    23221 aaacctgccc gaacgaactg gtttaatctt gccgctcccc tgcattccag gggagctgat
    23281 tcagataatc cccaatgacc tttcatcctc tattcttaaa atagtcctga gtcagaaact
    23341 gtaattgaga accacaatga agaaagtagc cgcgtttgtt gcgctaagcc tgctgatggc
    23401 gggatgtgta agtaatgaca aaattgctgt tacgccagaa cagctacagc atcatcgctt
    23461 tgtgctggaa agcgtaaacg gtaagcccgt gaccagcgat aaaaatccgc cagaaatcag
    23521 ctttggtgaa aaaatgatga tttccggcag catgtgtaac cgctttagcg gtgaaggcaa
    23581 actgtctaat ggtgaactga cagccaaagg gctggcaatg acccgtatga tgtgcgctaa
    23641 cccgcagctt aatgaactcg ataacaccat tagcgaaatg ctgaaagaag gtgcacaagt
    23701 ggatctgacc gcgaaccagt taacgctggc gaccgcaaaa cagacattaa cttataagct
    23761 ggcggattta atgaattaat agctgccaca gctcccggcg gcaagtgact gttcgctaca
    23821 gcgtttgccg ttgggtaatg cacacatccc aatcgccgta ccatccagtt gacgggcaac
    23881 agaaagcgaa ccgccgatca ttgcacaatt tgcttctcca ctactggaca tcgacgcttt
    23941 taaacctggc gctacgtgcg cggcagtcgc ctgctgaaca ggttcactac tacacgccga
    24001 caacaataaa gcggcacacc ctacccaaaa cgctgctcgc atcttttctt cctctgatct
    24061 tcaagccaaa cgacaccgcc ataaataata ggcagcacag agggcggcgt cgagagctgt
    24121 cctgcgcgtt gccccgcatt tttacttttt tatggctatt tttttgccct ctgtttgatc
    24181 aaaacattca ttacgctgat gtgggggaca caaaagcgaa aatgcagaag aaagccattt
    24241 gctaaaattg aaagattact actgggcgcg cagcaatttc gtgcgcccct catttgcgca
    24301 atgtaagggt gtcatatgat tactattgac ggtaatggcg cggttgcttc ggtcgcattt
    24361 cgcaccagtg aagttatcgc catctaccct attaccccca gttccacgat ggcagaacag
    24421 gctgatgcct gggccggaaa cggcttaaag aacgtttggg gagacacacc acgcgtggtt
    24481 gaaatgcagt cggaagcggg tgctatcgct accgtgcatg gcgctttgca gacgggtgcc
    24541 ctttcaacat cgtttacgtc atcgcagggt ttgctgctga tgatcccgac gctgtacaaa
    24601 ctggcaggcg aactaacacc gtttgtcctg catgtagcgg cacgtaccgt tgccacacat
    24661 gcactctcta tttttggcga tcattccgac gttatggcgg tgcgccagac gggttgcgcg
    24721 atgttgtgtg cagcaaacgt ccaggaagcg caagactttg ctctcatttc gcaaatcgcg
    24781 acgctgaaaa gccgcgtgcc atttattcat ttctttgatg gtttccgcac gtcccacgaa
    24841 atcaataaaa ttgtcccgct ggccgatgac acgattcttg atctcatgcc gcaggtcgaa
    24901 attgatgctc atcgcgcccg ggcactcaac ccggaacatc cggtgatccg cggtacgtcc
    24961 gccaatcctg acacttattt ccagtctcgc gaagccacca acccatggta caacgcggtc
    25021 tatgaccatg ttgaacaggc gatgaatgat ttctctgccg cgacaggtcg tcagtatcag
    25081 ccgtttgaat attacgggca tccgcaagcg gaacgggtga ttatcctgat gggctctgcc
    25141 attggcacct gtgaagaagt ggttgatgaa ttgctaaccc gtggcgaaaa agttggcgtg
    25201 ctgaaagttc gcctgtaccg ccccttctcc gctaaacatt tactgcaagc tctgccggga
    25261 tccgtacgca gcgtggcggt actggacaga accaaagaac ccggtgccca ggcagaaccg
    25321 ctctatctgg atgtaatgac cgcactggca gaagccttta ataatggcga gcgcgaaact
    25381 ctgccccgtg tcattggtgg gcgctatggt ctttcatcca aagaatttgg cccagactgt
    25441 gtactggcgg tatttgccga gctcaacgcg gctaaaccga aagcgcgctt tacggttggt
    25501 atttacgatg atgtgaccaa tctgtcactg ccgttgccgg aaaacaccct gccaaactcg
    25561 gcgaaactgg aagccttgtt ttatggcctt ggtagtgatg gcagcgtttc cgcgaccaaa
    25621 aacaatatca agattatcgg taattccacg ccgtggtacg cacagggcta ttttgtttac
    25681 gactccaaaa aggcgggcgg cctgacggtt tctcaccttc gagtgagcga acagccgatt
    25741 cgttccgctt atctcatttc ccaggctgat tttgttggct gccaccagtt gcagtttatc
    25801 gataaatatc agatggctga gcgtttaaaa cctggcggca ttttcctgct caacacgccg
    25861 tacagcgcag atgaagtgtg gtcgcgcttg ccgcaagaag ttcaggccgt gttaaaccag
    25921 aaaaaagcgc gcttctatgt gattaacgcg gcgaaaatcg cccgcgaatg tggcctggcg
    25981 gcccgtatta ataccgtcat gcagatggct tttttccatc tgacgcaaat tctgcctggc
    26041 gatagcgccc tcgcagaatt gcagggtgcg attgccaaaa gttacagtag caaaggccag
    26101 gatctggtgg aacgcaactg gcaggctctg gcgctggcgc gtgaatccgt agaagaagtt
    26161 ccgttgcaac cggtaaatcc gcacagcgcc aatcgaccgc cagtggtttc cgatgccgcc
    26221 cctgatttcg tgaaaaccgt aaccgctgcg atgctcgccg ggcttggtga cgccctcccc
    26281 gtttcggcgc tgccgccaga cggcacctgg ccgatgggca ctacgcgctg ggaaaaacgc
    26341 aatatcgccg aagagatccc catctggaaa gaggaactct gtacccaatg taaccactgc
    26401 gttgccgctt gcccacactc agctattcgc gcaaaagtgg tgccgcctga agcgatggaa
    26461 aacgcccctg ccagcctgca ttcgctggat gtgaaatcgc gtgatatgcg cgggcagaaa
    26521 tatgtcttgc aggtggcacc ggaagattgc accggttgta acctgtgcgt cgaagtttgc
    26581 ccggcgaaag accgtcagaa tccagagatt aaagccatca atatgatgtc tcgcctggaa
    26641 catgtcgaag aagagaaaat caattacgat ttcttcctca acctgccaga aatcgaccgt
    26701 agcaaactgg aacgtattga tattcgtaca tcgcagctga ttacaccgct gtttgaatat
    26761 tcaggtgctt gctccggttg tggcgagacg ccgtatatta aattactgac tcagctctat
    26821 ggcgaccgga tgttgatcgc taacgccact ggctgttctt caatttatgg cggtaacctg
    26881 ccctctacac cgtataccac cgatgccaac ggtcgtgggc cggcatgggc gaactctcta
    26941 tttgaagata atgccgaatt tggccttggt ttccgcctga cggtcgatca acaccgtgtc
    27001 cgcgtgctgc gtctgctgga tcaatttgcc gataaaatcc cggcggaatt actgacggcg
    27061 ttgaaatcag acgccacgcc agaggttcgt cgtgaacagg ttgcagcttt acgccagcaa
    27121 ctcaacgatg ttgccgaagc acatgaactg ctacgtgatg cagatgcact ggtggaaaaa
    27181 tcaatctggc tgattggtgg tgatggctgg gcttacgata tcggctttgg cggtctggat
    27241 catgtattga gtttgacgga aaacgtcaac attctggtgc tggatacgca atgctattcc
    27301 aacaccggtg gtcaggcgtc gaaagcgaca ccgctgggtg cagtaactaa atttggcgag
    27361 cacggcaaac gtaaagcgcg taaagatctt ggcgtcagta tgatgatgta cggtcatgtt
    27421 tatgtggcgc agatttctct cggcgcgcag ctgaaccaga cggtgaaagc gattcaggaa
    27481 gcggaagcgt atccggggcc atcgctgatc attgcttata gcccgtgtga agagcatggt
    27541 tacgatctgg cactcagcca cgaccagatg cgccaactca cagctaccgg cttctggccg
    27601 ctatatcgct ttgatccgcg tcgtgccgat gaaggcaaac tgccgctggc cttggattca
    27661 cgcccgccgt cagaagcact ggaagaaacg ttacttcacg agcaacgttt ccgtcggctg
    27721 aattcgcagc agccagaagt ggcagaacag ttatggaaag atgctgcagc tgatttgcaa
    27781 aaacgctatg acttcctggc acaaatggcc ggaaaagcgg aaaaaagcaa caccgattaa
    27841 atgctctgga taaggattat ccaattctaa aaaaaaagcc cggacgactg ttcgggcttg
    27901 tctttttata tgttggaaaa tcagtggcaa tgcaatggcc caacagaaaa taaaatctgt
    27961 gacaataaag gcatataacc cgcgcagaat aac
//
LOCUS       DAPHKZ010000054        27813 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.054, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000054 DAPHKZ010000000
VERSION     DAPHKZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27813
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.054"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            65..322
                     /gene="bhsA"
                     /locus_tag="RH288_002429"
     CDS             65..322
                     /gene="bhsA"
                     /locus_tag="RH288_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple stress resistance protein BhsA"
                     /protein_id="HDV4031476.1"
                     /translation="MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAG
                     TNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAVIYK"
     gene            complement(404..1366)
                     /gene="ldtC"
                     /locus_tag="RH288_002430"
     CDS             complement(404..1366)
                     /gene="ldtC"
                     /locus_tag="RH288_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtC"
                     /protein_id="HDV4031477.1"
                     /translation="MMIKTRFSRWLTFFTFAAAVALALPAKANTWPLPPAGSRLVGEN
                     KFHVVENDGGSLEAIAKKYNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPRE
                     GIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTAN
                     IRARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCI
                     RLRDDDIKTLFSQVTPGTKVNIINTPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPI
                     TLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL"
     gene            complement(1510..4956)
                     /gene="mfd"
                     /locus_tag="RH288_002431"
     CDS             complement(1510..4956)
                     /gene="mfd"
                     /locus_tag="RH288_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDV4031478.1"
                     /translation="MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPTMQ
                     RGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEAINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLLVNTGDLETSAERFQADTLARFENRGVDPMRPLLPPQSLWLRVDELFSELKNW
                     PRVQLKTEHLPTKAANANLGFQKLPDLAVQTQQKAPLDALRKFLETFDGPVVFSVESE
                     GRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDTVRNLALICESDLL
                     GERVARRRQDSRRTINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     ISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKE
                     RIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSMVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKTENELEEIKVELIDRFGLLPDPARTLLDIARLRQQAQKLGIRKLEGNEKGGVIE
                     FAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENA
                     IA"
     gene            complement(5084..6157)
                     /locus_tag="RH288_002432"
     CDS             complement(5084..6157)
                     /locus_tag="RH288_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HDV4031479.1"
                     /translation="MKQKELWINQIKGLCICLVVIYHSVITFYPHLTTFQHPLSEVLS
                     KCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQW
                     LALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASTSLWYLYALIVYFVVCKIF
                     SRLALPLFALFVLLSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATIMTCVKEVPLR
                     RHLLMASLLTVLAVGAWLFTISLLLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSN
                     TIAIYTTHRILVEIFSLTLLAQMNAARWSPQVELTLLLVYPFVSLFICTVAGLLVRKL
                     SQRAFSDLLFSPPSLPAAVSYSR"
     gene            6419..7618
                     /gene="lolC"
                     /locus_tag="RH288_002433"
     CDS             6419..7618
                     /gene="lolC"
                     /locus_tag="RH288_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HDV4031480.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
                     QIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGN
                     ITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGA
                     LLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            7611..8312
                     /gene="lolD"
                     /locus_tag="RH288_002434"
     CDS             7611..8312
                     /gene="lolD"
                     /locus_tag="RH288_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415635.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HDV4031481.1"
                     /translation="MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEINSRALEMLKAVGLDHRANHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            8312..9556
                     /gene="lolE"
                     /locus_tag="RH288_002435"
     CDS             8312..9556
                     /gene="lolE"
                     /locus_tag="RH288_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HDV4031482.1"
                     /translation="MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDHVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKV
                     KQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMG
                     SSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     VLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCG
                     VIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            9585..10496
                     /gene="nagK"
                     /locus_tag="RH288_002436"
     CDS             9585..10496
                     /gene="nagK"
                     /locus_tag="RH288_002436"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDV4031483.1"
                     /translation="MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVC
                     ELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRL
                     PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQG
                     DEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLADRLPRHLLPV
                     ARVPRIERARHGDAGGMRGAAFLHLTD"
     gene            10512..11351
                     /gene="cobB"
                     /locus_tag="RH288_002437"
     CDS             10512..11351
                     /gene="cobB"
                     /locus_tag="RH288_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415638.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDV4031484.1"
                     /translation="MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQP
                     EIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
                     VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGLKAG
                     SIA"
     gene            complement(11471..12259)
                     /locus_tag="RH288_002438"
     CDS             complement(11471..12259)
                     /locus_tag="RH288_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HDV4031485.1"
                     /translation="MKKFIILLSLLILLPLTAASKPLIPIMKTLFTDVTGTVPDAEEI
                     AHKAELFRQQTGIAPFIVVLPDINNEASLRQNGKAMLAHASSSLSDVKGSVLLLFTTR
                     EPRLIMITNGQVESGLDDKHLGLLIENHTLAYLNADLWYQGINNALAVLQAQILKQST
                     PPLTYYPHPGQQHENAPPGSTNTLGFIAWAATFILFSRIFYYTTRFIYALKFAVAMTI
                     ANMGYQALCLYIDNSFAITRISPLWAGLIGVCTFIAALLLTSKR"
     gene            complement(12256..12717)
                     /locus_tag="RH288_002439"
     CDS             complement(12256..12717)
                     /locus_tag="RH288_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3592 domain-containing protein"
                     /protein_id="HDV4031486.1"
                     /translation="MSQDSKVFFRIFLGIGLVLILISVVVFYNQFTYSKDAIHTEGVI
                     VDTVWHSSHSHRTGKDGSWYPVVAFRPTPDYTLIFNSSIGSDFYEDSEGDKVNVYYSP
                     GHPEKAEINNPWVNFFKWGFIGIMGVIFIAVGLLISMPSSKKSRRKRKSRP"
     gene            complement(12775..13821)
                     /gene="potD"
                     /locus_tag="RH288_002440"
     CDS             complement(12775..13821)
                     /gene="potD"
                     /locus_tag="RH288_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HDV4031487.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLTNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
                     GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGAAS
                     SIYEEYYQKLKAGR"
     gene            complement(13818..14612)
                     /gene="potC"
                     /locus_tag="RH288_002441"
     CDS             complement(13818..14612)
                     /gene="potC"
                     /locus_tag="RH288_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HDV4031488.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKI
                     YSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK"
     gene            complement(14609..15466)
                     /gene="potB"
                     /locus_tag="RH288_002442"
     CDS             complement(14609..15466)
                     /gene="potB"
                     /locus_tag="RH288_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HDV4031489.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASR
                     LLNKKVELE"
     gene            complement(15450..16586)
                     /gene="potA"
                     /locus_tag="RH288_002443"
     CDS             complement(15450..16586)
                     /gene="potA"
                     /locus_tag="RH288_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HDV4031490.1"
                     /translation="MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGREC
                     NIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK"
     gene            16836..18062
                     /gene="pepT"
                     /locus_tag="RH288_002444"
     CDS             16836..18062
                     /gene="pepT"
                     /locus_tag="RH288_002444"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDV4031491.1"
                     /translation="MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEE
                     MGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKKI
                     PHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTAQRK"
     gene            complement(18111..19232)
                     /gene="roxA"
                     /locus_tag="RH288_002445"
                     /gene_synonym="ycfD"
     CDS             complement(18111..19232)
                     /gene="roxA"
                     /locus_tag="RH288_002445"
                     /gene_synonym="ycfD"
                     /EC_number="1.14.11.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415646.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[50S ribosomal protein L16]-arginine
                     3-hydroxylase"
                     /protein_id="HDV4031492.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLA
                     MESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRE
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYV
                     LQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALD
                     ALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(19308..20768)
                     /gene="phoQ"
                     /locus_tag="RH288_002446"
     CDS             complement(19308..20768)
                     /gene="phoQ"
                     /locus_tag="RH288_002446"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HDV4031493.1"
                     /translation="MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDV
                     PWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
                     VNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSL
                     RPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLS
                     RELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACK
                     YCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAR
                     EITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE"
     gene            complement(20768..21439)
                     /gene="phoP"
                     /locus_tag="RH288_002447"
     CDS             complement(20768..21439)
                     /gene="phoP"
                     /locus_tag="RH288_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HDV4031494.1"
                     /translation="MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHI
                     PDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGY
                     LFELR"
     gene            complement(21608..22978)
                     /gene="purB"
                     /locus_tag="RH288_002448"
     CDS             complement(21608..22978)
                     /gene="purB"
                     /locus_tag="RH288_002448"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDV4031495.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKE
                     KVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQ
                     YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAIT
                     MVDELK"
     gene            complement(22982..23623)
                     /gene="hflD"
                     /locus_tag="RH288_002449"
     CDS             complement(22982..23623)
                     /gene="hflD"
                     /locus_tag="RH288_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HDV4031496.1"
                     /translation="MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSII
                     DMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL"
     gene            complement(23659..24765)
                     /gene="mnmA"
                     /locus_tag="RH288_002450"
     CDS             complement(23659..24765)
                     /gene="mnmA"
                     /locus_tag="RH288_002450"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415651.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDV4031497.1"
                     /translation="MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFD
                     EPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV"
     gene            complement(24819..25280)
                     /gene="nudJ"
                     /locus_tag="RH288_002451"
     CDS             complement(24819..25280)
                     /gene="nudJ"
                     /locus_tag="RH288_002451"
                     /EC_number="3.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase NudJ"
                     /protein_id="HDV4031498.1"
                     /translation="MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETL
                     VEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDID
                     CCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI"
     gene            complement(25290..25943)
                     /gene="rluE"
                     /locus_tag="RH288_002452"
     CDS             complement(25290..25943)
                     /gene="rluE"
                     /locus_tag="RH288_002452"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415653.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HDV4031499.1"
                     /translation="MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPENQPTRVILF
                     NKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPG
                     KRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER
                     KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWREVTD"
     gene            26115..27365
                     /gene="icd"
                     /locus_tag="RH288_002453"
     CDS             26115..27365
                     /gene="icd"
                     /locus_tag="RH288_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HDV4031500.1"
                     /translation="MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     ANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIV
                     IKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYD
                     FERLMEGAKLLKCSEFGEAIIENM"
     gene            complement(27468..27791)
                     /gene="iraM"
                     /locus_tag="RH288_002454"
     CDS             complement(27468..27791)
                     /gene="iraM"
                     /locus_tag="RH288_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HDV4031501.1"
                     /translation="MKWIVIDTVIQPTCGISFSAIWGNMKMIIWYQSTIFLPPGSIFT
                     PVKSGIILKDKEYPITIYHIAPFNKDLWSLLKSSQECPPGESKITNKCLHNSCIIKIC
                     PYGLK"
BASE COUNT         6799 a         6999 c         7193 g         6822 t
ORIGIN      
        1 tcatttagtt atcgatcgtt aagtaattgc ttgcgacgtc attcatctgc ataaggccac
       61 tattatgaaa aacgtaaaaa ccctcatcgc tgcggcgatt ttaagctcca tgtcatttgc
      121 cagctttgcg gctgtcgaag ttcagtcaac gccagaaggc caacaaaaag tcggtacaat
      181 cagtgctaac gcggggacaa atctgggatc gctggaagag cagctggcgc aaaaagcgga
      241 tgagatgggc gcaaaatctt tccgtattac ttctgtaacc ggtccgaata ccctccatgg
      301 aacagcagta atttataaat aagcattaac cctcattaat gcctgctact gctgattttt
      361 tccccgcgac atgccgtgtc gcggggattt ttttatccgg gctttacagc gtttgtgggc
      421 tcacttgatg acggcggaca tccaccggca tcccggaacg gacatccatc acatgttgca
      481 tcacttcagc gtcagtttgt gctgcatctt taaatgattg cattgcgcta ttcagcgtaa
      541 ttggcagcag ctgcggatcg tcatcaatct tctctgacag cggctgatgt acttcaacca
      601 gacgcgcacc gtttggttcg gcagagactt ttatcggagt gttgatgata ttcactttgg
      661 tgcctggggt gacctggcta aagagtgttt tgatatcgtc atcccgcaga cgaatacagc
      721 cagaacttac ccgcatgcca atgccgaaat cggcgttcgt accatgaagc aaataaacgc
      781 cgccataggc cgccagacga atcgcatgat ggcccattgg gttatccggt ccagccggca
      841 ctaccgcagg caactcaatt ccctgtgctt tataacgggc gcggatgttt gccgttggcg
      901 tccaggttgg gtttgcacgt ttgtctgaaa cggtggtcac cattgtcggt gtcagcgtgt
      961 caccacctaa ctgaccaata cctattggat acacggttac cgaattttta cccggcgggt
     1021 agtaatagag acgcagctcc gcaatgttga tcacaatgcc ttcgcgcggc gcatctggaa
     1081 gtagggtttg caacgggatc gttaacacgc tgcccgcgcg cggtacgtaa ggatcaacgc
     1141 cggggttagc ctgtaacaga gcgagaaagc cgacgttgta ttttttggcg atggcttcca
     1201 gagaaccacc gtcattttcc accacatgaa atttgttttc gccaaccaga cgactgcccg
     1261 ctggcggcag cggccaggtg ttggcttttg ccggtagcgc cagcgccacg gcagcggcga
     1321 acgtaaaaaa cgttagccag cgagaaaaac gcgttttgat catcaccaaa aatccataat
     1381 aaatataagg ttattgtaat aaacagataa gcctgaatta tggatggtga cagtgtcgga
     1441 tagtgcaggg aagtgcaaag aatttgtaaa tgttgcagat gggggcgcag aaacgccccc
     1501 gatttaccat taagcgatcg cgttctcttc cagttcacgc ataaactggc gtacccattc
     1561 gatacgcgtt ttccgctcac tcaaatcctg aataaatttc aggcgcgtcg gaccatcaag
     1621 gcggtaatgc tgcggctgtt tttgcagcaa accaatcaac caggccggat taacgtgatt
     1681 cttctcggca aattcgatca ccccgccttt ctcattacct tccagcttcc tgatccccag
     1741 tttctgcgct tgctggcgca gacgggcaat atccagcagg gtacgcgccg gatctggcag
     1801 caggccgaag cgatcgataa gctcgacttt gatctcttcc agttcgtttt ccgttttggc
     1861 gctggcaata cgtttgtaga acgacagacg cgtgttcacg tcagggatga aatcatctgg
     1921 caatagcgac ggcatccgca gctcgacttc tgtttgctgg ctggtgagat cttccagcga
     1981 cggctcgcgt ccggctttca gtgcatcgac ggcgttttcc agcaactcca tatacagcga
     2041 gaaaccgatg gtttccattg agccgctttg ttcttcgcca agcagttcac ccgcgccgcg
     2101 aatctccaga tcgtgcgttg ccagcgcaaa acctgccccg agatcttcca gcgaggcaat
     2161 tgcttcaaga cgtttttgtg catcggtagt catcgctttt ggatgcggtg tcagcaacca
     2221 tgcatatgcc tgatgatgcg aacgtccgac gcgaccgcgt aactggtgca gctgcgccag
     2281 accgaagtga tccgcgcgtt caatgataat agtgttggct gtcgggatgt cgatcccggt
     2341 ttcgataatg gttgtacaaa ccagcacgtt gaaacgttga tgatggaaat cattcatcac
     2401 ccgttccagt tcgcgctcgc gcatctgccc gtgaccgatg gcgatccgcg cttctggcac
     2461 cagttctgcc agccgttcgg cggctttctg aatgttttcc acatcattgt agagataata
     2521 aacctgtcct ccgcgcaaaa tttcacgcag gatcgcctcc cggaccacca tgctgtcata
     2581 ctcacggaca aaggttttaa ctgccagacg acgggcgggc ggcgtggcga taatcgacag
     2641 atcacgcatt ccgctcattg ccatattcag cgtacgtggg atcggcgttg cagtaagcgt
     2701 cagaatatcc acgttcgcgc gcatcgcttt aatgcgctct ttatgacgca ccccgaagcg
     2761 gtgttcttca tcgacaatca gcaggcctaa atctttaaac ttgacgtcac tttgcagcag
     2821 tttgtgcgta ccgatcagaa tatcgatttt cccttccgcc acttccgcaa ggatttgcgt
     2881 ctgctctttg gcgctgcgga aacgggagat catttcgata cgtaccggcc agttggcgaa
     2941 acggtcgcgg aagttgtcgt aatgctgctg cgcgagaagg gtggtaggca ccagcaccgc
     3001 cacctgcttg tggttatcta ctgccaggaa agctgcgcgc atcgccactt ctgttttacc
     3061 aaagccaaca tcgccgcaca ccagacgatc cattgccagc ggctgacaca tgtcgctaag
     3121 taccgcatta atggcctgcg cctgatccgg cgtggtttca aacgggaagc tgtcgcagaa
     3181 caactgatac tgctcacgat cgtgtttaaa cgcgaagccc tctttggcgg cgcgttgcgc
     3241 gtagatatcc agcaattccg ccgccacatc acgcactttt tccgccgctt tctgccgcgc
     3301 gcgtgaccac gcatcgccgc caagtttatg cagcggggcg ttttcttccg cgccacctgc
     3361 gtaacggcta atcagatgca gtgacgacac cggaacatac agtttggcgt cgttggcata
     3421 ggtgagcatc agatactcgc cagtaatgcc acccgcttcc agcgtggtca ttccggcata
     3481 acgaccgacg ccgtgctcca gatggaccac cggctgacca atatgcagtt ccgcaaggtt
     3541 acggatcagt gtatcggggt tgatggtgcg gcgagaatcc tgacgacgac gggcaacgcg
     3601 ttcaccgagc agatcgcttt cgcaaatcag cgccagatta cgcaccgtat cgacaaaacc
     3661 atgttcggca gcgccaatca tcagataacg cccacggtcg ctggcttcat caagacgcat
     3721 aatgcgttgc ggagcaattt taattcgtgc gagcagttca cccagcgctt cacggcgacc
     3781 ttcactttct accgagaaca ccaccggacc gtcgaaagtc tcgaggaact tacgcagcgc
     3841 atccagcggc gctttttgtt gtgtctgaac ggccaggtct ggcagtttct ggaaacctaa
     3901 attggcattc gcggcttttg tcggtaaatg ttcagttttt agctgcaccc ggggccagtt
     3961 tttcagctct gagaagagct cgtccacccg cagccagagc gattgtggtg gcaacagcgg
     4021 gcgcatcgga tcgacgccgc gattctcaaa acgcgccagc gtgtcagcct ggaaacgttc
     4081 ggcactggtt tccagatcgc cagtattcac gagcaaggta ttggcaggga aataactgaa
     4141 cagcggcggc agtggttcgc tgaagaacaa tggctgccag tactcgatcc cggcaggtaa
     4201 tgtgccttta ctcacttgct ggtaaatatg ttctggatcg cgcttcactt cgaaggtatc
     4261 gcgccactgg ctgcggaaca gttcaattgc cgctttatcg gtcggaaatt cgtgcgcggg
     4321 cagcagattg atcgcttcta cttcctccag cgtgcgctgg ctgtcgacgt caaacacccg
     4381 caggctgtcg atttcatcat caaagaaatc aagacgataa ggcagctcac tccccatcgg
     4441 gaagagatcc agcaacgcgc cgcgcgtggc gtattcgccg tgctccatca cctggtcaac
     4501 atggcgataa ccggcgctgt ccagttgggt tcgtaatgca tctcgtgaca ggcgctgacc
     4561 ttttttcatc accagcgcat gaccgtggag aaaactgtgt gggcaaacgc gctgcataag
     4621 cgtattcacc ggaacaatca gtacgccacg ctgcatcgtc ggtagctggt aaagggtgga
     4681 aaggcgcgag gagataatgt cctgatgagg cgaaaaactg tcgtagggaa gagtttccca
     4741 gtccgccaga ttcatcacca tttgatcggt aaactggctg atttcatcat gcaaacgcag
     4801 agcattttgc atatctggtg caatgagtac caccggaccg gcgtgacgtt cggcaatttc
     4861 cgctaccagc gttgcacagg ctgcgccggt taactcgccc agcagacgct gctcacccgc
     4921 tttgacgggc agcgtataac gatattgttc aggcataacg gttgtcagat tctcgttagg
     4981 atatgcctca acatatgggg gcatatctct gataagcaat gctgttcatt atccgtaatc
     5041 gacatggttt agcaaattga atcgccccgg ctggggcgat ggcttagcgg gagtaactga
     5101 cggcagcggg cagtgaaggc ggggagaaca acagatcgct gaatgcacgc tgtgaaagtt
     5161 ttcttaccag caagcccgca acagtacaga tgaacaaact gacaaaggga taaaccagca
     5221 ggagtgtcag ttcgacttgc ggcgaccagc gtgctgcgtt catttgcgca agcagagtta
     5281 agctgaatat ttcaaccaga atgcgatggg tggtgtagat agcaatggtg ttggagccaa
     5341 tcacattcag caggctggtg gagcgcatac cgaatcgttg ctcgtattga taaaacagct
     5401 tcatgatcac cacaatcgat accagcgaca acagcagcga gatagtaaac aaccaggcac
     5461 cgaccgccag aacggtaagc aaagaagcca tcagcagatg gcggcgcaac ggcacctctt
     5521 taacacaggt cattattgtt gcgccaaacc atgcgccaag gctgtaataa ggcaaattgc
     5581 ggatcacact gttcattccc caccacggcg tgggaacgaa attaaccgcc acactcagca
     5641 gtacaaacaa ggcgaatagt ggcagcgcca gacggctaaa aattttacat accacgaaat
     5701 agacaattaa cgcatacaga taccacaagc tggtgctggc ggtgatcatc ccgtgcagga
     5761 actcaccggt ggaatcggca taagcggcat tggaggcatt gcttaaatcg cgctcaggtg
     5821 ccagccactg gttcagcgca cttaacgcca gccactgcac cacgccccaa agcgccagca
     5881 cccagaagat gttccagatc cgtttatcga gacaatttcc ccacggtacg ctgtcgatat
     5941 agcggcgaat caaatagccg gatataaaga aaaaaaccgg catacgaaag ggggcaaggt
     6001 aaagattgaa atagatccag catttgctca ggacttccga taacggatgc tgaaaagtgg
     6061 tcagatgcgg ataaaaggta atgaccgagt gataaatcac caccagacaa atacataacc
     6121 ctttgatctg gttaatccat agctcttttt gtttcatcag gacaacacgc tcttttttaa
     6181 tttacatgcg gttgatcctg cgggttatga cccgaggtgt aatgggtatc tgtctgtatt
     6241 ggatgatttt tcagattaag atcaggcggc aagattgatg ataaaacatg gcaatttagc
     6301 cgattgattt acgggggctt ttcagattag ccctgacgat cacttacagt tcagacgttt
     6361 acccatcttg ctttcgctta tatactcgtg tctttgctac agcaaccaga cggatttcat
     6421 gtaccaacct gtcgctctat ttattggcct gcgttacatg cgtgggcgtg cagcggatcg
     6481 cttcggtcgt ttcgtctcct ggctttctac catcggcatt accctcgggg tgatggcgct
     6541 ggtcacagta ttgtcagtga tgaacggctt tgagcgcgag ctgcaaaaca acatccttgg
     6601 cctgatgcca caggcaattc tctcttctga gcatggctct cttaacccgc agcaactccc
     6661 agaaacggca gtcaaactgg acggcgttaa tcgcgtcgca cctattacta ccggtgatgt
     6721 ggtactgcaa agcgcgcgca gcgtggcggt cggggtgatg ctcggtatcg acccggcgca
     6781 aaaagatcca cttacaccgt atctggtcaa tgtgaaacaa actgacctcg agccggggaa
     6841 atataatgtc atcctcggcg aacaacttgc ctcacagcta ggcgttaatc gcggtgatca
     6901 aatccgcgtg atggtaccat ctgccagcca gttcacgccg atggggcgta ttccaagcca
     6961 gcgcctgttc aatgtgattg gcactttcgc cgccaacagt gaagtcgatg gctatgaaat
     7021 gctggtgaat attgaggatg cctcgcgtct gatgcgttat ccggcaggca atattaccgg
     7081 ctggcgtttg tggctggatg agccgctgaa agtcgactca ttaagtcagc aaaaactgcc
     7141 tgaaggcagc aaatggcagg actggcgtga tcgtaaaggc gagttgttcc aggccgtacg
     7201 catggaaaaa aatatgatgg gtttactgct gagcctgatt gtcgccgttg cggcgtttaa
     7261 cattattacc tcactagggc tgatggtaat ggagaagcag ggcgaagtag cgatcctgca
     7321 aacgcaaggc ttaactccgc gacaaatcat gatggtcttt atggtgcaag gggccagcgc
     7381 cgggattatc ggtgcgatcc tcggagcggc gcttggcgcc ctgcttgcca gccagttaaa
     7441 taatctgatg ccgataatcg gcgtcctgct tgatggcgcg gcgctgccgg tggctatcga
     7501 acctttacag gtcattgtta ttgcgctggt ggcgatggct atcgcgctgc tgtctacgct
     7561 ttacccttca tggcgcgctg ccgccactca acccgctgag gctttacgtt atgaataaga
     7621 tcctgttgca atgcgacaac ctgtgcaaac gctatcagga aggcagtgtg caaaccgatg
     7681 tgctgcacaa tgtcagtttc agcgtcggcg aaggtgaaat gatggcgatc gtcggtagct
     7741 ctggttccgg taaaagtacc ttgctgcacc tgctgggcgg gctggatacg ccaacctccg
     7801 gcgatgtgat ttttaatggt cagccaatga gcaaactgtc gtcggcagcg aaagctgaac
     7861 tgcgcaacca gaagctgggc tttatttatc agtttcacca cctgctgccg gattttaccg
     7921 ccctggaaaa cgtggctatg ccgctgctga ttggcaagaa aaagcccgct gaaatcaaca
     7981 gccgtgcact tgagatgtta aaagcggtgg ggctggatca tcgtgcgaat caccgcccat
     8041 ctgaactttc tggcggcgaa cgccagcgtg tggcgattgc ccgtgcgctg gtgaataacc
     8101 cgcgcctggt actggcggat gaacctaccg gtaacctcga tgcgcgtaac gccgacagca
     8161 tcttccagtt gcttggggaa ttgaatcgct tgcagggcac cgccttcctg gtggttactc
     8221 acgacctgca actggcgaaa cgtatgagcc gccagttaga aatgcgtgat ggtcgtctga
     8281 cggcggaact gagcctgatg ggggcggagt aatggcgatg cctttatcgt tattaattgg
     8341 cctgcgtttt agtcgcggac ggcggcgcgg cggcatggtg tcgctgatct ccgttatttc
     8401 taccattggc attgccctcg gcgtggcggt attgatcgtc ggcttaagcg cgatgaacgg
     8461 ctttgaacgc gaactgaaca accgtattct ggcggtggtg ccgcatggtg aaatcgaggc
     8521 ggtggatcag ccgtggacta actggcagga agcactggat cacgtgcaaa aagtgccggg
     8581 tattgccgct gccgcgccgt atatcaattt caccgggctg gtggaaagtg gcgcgaatct
     8641 tcgcgcaatc caggtgaagg gcgttaaccc gcaacaggaa cagcgtctga gcgcattacc
     8701 ctcgtttgtc cagggcgatg cgtggcgcaa ttttaaagcg ggcgaacagc aaattatcat
     8761 cggcaaaggc gtggcggatg cgctgaaagt gaagcagggg gattgggtgt cgattatgat
     8821 ccccaactcg aatcccgagc ataaactgat gcagccaaaa cgtgtgcgtt tgcacgttgc
     8881 cggtattttg cagttgagtg gtcaactcga tcacagtttt gccatgatcc cgctggcgga
     8941 tgcccaacaa tatcttgata tgggttccag cgtgtcaggt attgccctta aaatgacgga
     9001 tgttttcaac gccaataagc tggtacgcga tgcgggtgaa gtgaccaata gctatgttta
     9061 tattaaaagc tggattggta cttacggcta tatgtatcgc gatatccaaa tgatccgcgc
     9121 cattatgtat ctggcgatgg tactggtgat tggcgtggcc tgtttcaaca tcgtctccac
     9181 cttagtgatg gcggtgaaag acaagagtgg cgatatcgca gtattaagaa cgctgggggc
     9241 gaaagatggt ttaattcgcg ccatctttgt ctggtatgga ttgctggcag ggctgttcgg
     9301 cagcctgtgt ggtgtgatta tcggcgtagt ggtttcactg caacttaccc cgattattga
     9361 gtggattgaa aagttgatcg gtcatcagtt cctctccagc gatatctatt ttattgattt
     9421 cctgccatcg gaattgcact ggctggacgt cttctacgta ctggtcacag cattgttgct
     9481 gagtcttttg gcaagttggt atccggcgcg gcgcgccagt aatattgacc ctgcgcgagt
     9541 ccttagcggc cagtaaaggc agtacattaa aacaaggagc ggcaatgtat tacgggtttg
     9601 atattggtgg aacaaaaatt gcgcttggcg tgtttgatag cggtcggcag ttgcagtggg
     9661 aaaagcgggt gccgacaccg cgtgacagct atgacgcatt tttagatgca gtgtgtgagc
     9721 tggtagctga agctgaccaa cgttttggct gtaaaggttc tgtcggcatc ggtattccgg
     9781 gaatgccgga aacagaagat ggtacgctgt atgccgccaa tgtccccgct gccagcggta
     9841 aaccgctgcg tgccgacctg agcgcacgtc ttgatcgcga tgtacgcctt gataacgatg
     9901 ccaactgttt tgccctttca gaagcctggg atgatgaatt tactcaatat ccactggtga
     9961 tggggttgat tctcggcacc ggtgttggcg gcgggctgat tttcaacggc aaaccgatta
    10021 ccggtaaaag ctacattacc ggcgagtttg gccatatgcg tctgccggtt gatgcgttaa
    10081 ccatgatggg gttggatttc ccgttacgcc gctgcggctg tggtcagcat ggctgcattg
    10141 aaaattatct gtctggtcgc ggttttgcgt ggctgtatca acactattat catcaaccgt
    10201 tgcaggctcc cgaaattatt gcgctttatg atcaaggcga tgagcaggca agggcgcacg
    10261 ttgagcgtta tctggattta ttagcggttt gtctgggaaa tatcctgacc atcgttgacc
    10321 ctgacctggt cgtcattggt ggtggcttat cgaatttccc ggcaatcaca acgcaactgg
    10381 cggacaggct gcctcgtcat ctcttacctg tagctcgtgt tccgcgcatt gaacgcgcgc
    10441 gccacggtga tgcgggagga atgcgtggtg cggccttcct acatctaacc gattaaacaa
    10501 cagaggttgc tatgctgtcg cgtcggggtc atcggttaag tcgttttcgt aaaaataaac
    10561 gccgcctgcg cgagcgtttg cgtcagcgta tttttttcag agataaagtg gtgccggaag
    10621 caatggaaaa accaagagta ctcgtactga caggggcagg aatttctgcg gaatcaggta
    10681 ttcgtacctt tcgcgccgca gatggcctgt gggaagaaca tcgggttgaa gatgtggcaa
    10741 cgccggaagg tttcgatcgc gatcctgaac tggtgcaagc gttttataac gcccgtcgtc
    10801 gacagctgca gcagccagaa attcagccta acgccgcgca tcttgcgctg gctaaactgc
    10861 aagacgccct cggcgatcgc tttttgctgg tgacgcagaa tatcgacaac ctgcatgaac
    10921 gcgcaggtaa taccaatgtg attcatatgc atggggaact gctgaaagtg cgttgttcac
    10981 aaagtggtca ggttctcgac tggacaggag acgttacccc agaagataaa tgccattgtt
    11041 gccagtttcc ggcacccttg cgcccgcacg tagtgtggtt tggcgaaatg ccactcggca
    11101 tggatgaaat ttatatggcg ttgtcgatgg ccgatatttt cattgccatt ggcacatccg
    11161 ggcatgttta tccggcggct gggtttgttc acgaagcgaa actgcatggc gcgcacaccg
    11221 tggaactgaa tcttgaaccg agtcaggttg gtaatgaatt tgccgagaaa tattacggcc
    11281 cggcaagcca ggtggtgcct gagtttgttg aaaagttgct gaagggatta aaagcgggaa
    11341 gcattgcctg atgcactacg cttatcaggc ctgcaagggg acgcaattaa ttgaatttgc
    11401 gggttttgtg ggccggataa ggcgttcgcg ccccatccgg cataatacac gcgcactttt
    11461 ccggcctctt ttatcgttta ctcgtcaata acaatgcggc aataaacgta cagacaccaa
    11521 ttagccctgc ccagagtggc gatattctgg taatcgcaaa gctattatcg atatacaaac
    11581 ataaagcctg ataacccata ttggcaatag tcatcgccac tgcaaatttt aacgcataaa
    11641 taaaacgagt cgtgtagtaa aagatcctgg aaaataagat aaacgtcgca gcccaggcga
    11701 taaaacctaa tgtgttggtg ctgccggggg gagcattttc atgctgttgt cctggatgcg
    11761 gataatacgt tagtggcggc gtcgattgtt ttaatatctg tgcttgtaga acagccaatg
    11821 cattattgat tccctgatac cagagatctg catttaaata agccagcgtg tgattttcta
    11881 tcagaaggcc gagatgttta tcgtccagac cactttcaac ctggccgttg gtgatcataa
    11941 ttaaccgtgg ttcgcgggta gtaaatagta acagaacact tccttttaca tcactcaatg
    12001 aagatgacgc atgcgccagc atcgctttac cattttgtct gagactggct tcattattaa
    12061 tgtcgggtaa aaccacaata aacggtgcaa ttcccgtttg ttggcgaaaa agctcggctt
    12121 tatgcgcgat ctcttcagca tctggtacag taccggtaac gtccgtaaaa agtgtcttca
    12181 ttattggaat taatggcttg ctggctgctg tcagaggcag gagtatcagt aaactgagca
    12241 gtataatgaa ttttttcatg ggcgggactt ccgtttcctg cgtgattttt tagaggaggg
    12301 catacttatt aataaaccga cggcgataaa aataacgccc ataatgccga taaaccccca
    12361 tttaaaaaaa ttaacccacg ggttatttat ctcagccttt tcaggatgcc cgggagaata
    12421 ataaacatta actttatcgc cttcgctgtc ttcataaaaa tcgctgccga tactcgaatt
    12481 gaaaattagc gtgtaatctg gcgtcggtcg aaaggcaacg acgggatacc acgaaccatc
    12541 tttacccgtg cgatgagaat gactggagtg ccagacggta tcaacaatga cgccttcggt
    12601 atgaatcgcg tctttgctat aggtgaactg gttataaaag acaacaacag aaatgaggat
    12661 cagtaccaga ccgataccga ggaatatacg aaagaaaact ttactgtcct gactcattag
    12721 ccacatcctt gctaactaaa aaacgggcgg taataccacc gcccgcttgc tgaattaacg
    12781 tcctgctttc agcttctgat aatactcttc ataaatgctg ctggctgcgc caacgtcatt
    12841 ctgccattcg ccatttttaa tggtttcagc atccgggtag agtgttttat cgttcgccac
    12901 ttctggactt aacagcttac gcgccgcaag gtttggcgtt ggataaccga tagtttcagc
    12961 aacctgtttt gccacatccg ggcgcagcag gaagttgatc aatttcagcg cgccttcttt
    13021 gtttttggca tttgccggga tcgccaggct gtccatccag aaaatgccgc cttctttcgg
    13081 ccacaccacg tcaattggcg tacccgcctg gcgtgcaacg aaagcagaac cgttccagat
    13141 catgccgagg ttaacttcgc cttccatgta cgggttcgcc gggttatcgg agttaaaggc
    13201 tgccacgttt ggcatcagtt ttttcagctc gttatatgca gcttcaatct ctttcggatc
    13261 ggtggtgtta ccggagtagc ccagcttacg cagcgccatc tggaacactt cacgggcatc
    13321 gtcggtcaac agcaggctgc ctttgtactc tggcttccac agatcggccc agctggtgac
    13381 agatttcgga tccaccgcat caccgttaac accaatcgcc gtcgcacccc agatatacgg
    13441 aatggagtag tcgttattcg ggtcaaaagg cttgttgagc atgtctggat cgagattgct
    13501 gaagtttgtt aacttcgact tgtcgatctt ctggatcatc ccttctttac gcattttatc
    13561 aacgtaatag gttgaaggaa ccaccagatc ataggcaccg tctttgtatg ttttcagctt
    13621 ggcgtacatg gtttcgttcg actcgtaagt cgaatagata accttaatac cggtttcttt
    13681 ggtgaactgt tcaagcagtc ctggcggcac gtactcggtc cagttgtaga aatacagcgt
    13741 gttgttgtca tcggcgtgag cggcgctcat gcccagtgcc agagcacccg ccgcgagcag
    13801 gtggcgtgac cattttttca tttaacgtcc cctgtgttac ctttcgtttt atcacgagca
    13861 ataagctggc tggcaataac catcaccagc gacagcacca gtaatatggt tgccagcgcg
    13921 ttaacttccg gcgatacgcc gactttgacc atcgaataaa tttttaacgg cagaatttca
    13981 taacttggtc cggtgacgaa cgaagaaact accacatcgt ccatcgacag ggtaaagctt
    14041 aacacccagc ccgccgccac cgctggcatt gccagtggca gaatgatttt tcgcagaatg
    14101 gtaaattcgc tggcaccgag atctttcgcc gcttccagca ttcgcacgtc aaaacctttc
    14161 aggcgcgaat acaccgtcac caccacaaat ggcaggcaga aggtgatatg cgagaacagc
    14221 agcgaccaga agccaagctg aatacccagc agcataaaca gcaccagcag cgaaatcgcc
    14281 atcacgatat ctggtgacat catcaccaca aacagcattc cgctaacgaa cggcttacca
    14341 cgaaagcgat aacggtacag cgcaactgcc gtcagtgaac cgataagcgt agcaaacgtc
    14401 gccgaaaaca ccgccattgt tagtgaatgc tgcgctgcct gtaacaggct gtcgttgttc
    14461 atcagcaggc tataccattt ggtggtaaaa ccctgccagt tgatgccaaa gcgcgagctg
    14521 ttaaaggagt tcacaatcaa aataatgatt gggatataca ggtacgcgta gatagcggtc
    14581 ataaaaccgc cgcgaagcag tcgaccgatc attcgagttc caccttctta ttcagcaaac
    14641 gagaagcgcg ccagtaaacc agcaacatca ggcccattac gatagtcagc gtaatgctgg
    14701 tagctgcacc aaacggccag tcacgaatat taaggaactg gaccttgatg acgttaccga
    14761 tcagcaggtt tttcgcaccg cccatcaggt cggatacata gaacaggccc atcgctggca
    14821 gcatcaccag cagacatccg gcaataattc ccggcatcgt cagtggaata atgatacgga
    14881 taaaagtctg taacttgctg gcaccgagat cgcgcgccgc ctcaagcaac ggcttatcca
    14941 gtttttcgat actggagtac agcggcatca ccataaacgg cagcagaatg taaaccagac
    15001 cgataatcac cgcactgggc gtgaacatga tacggattgg tgtgtcgata acgcccagcc
    15061 agagcaaaaa ctcgttgaga tagcctttgg tgctgaggaa aattttcagc ccgtagatac
    15121 gaattaatga gttggtccag aacggaacaa tcagcagaaa cagcagcagc ggacgcacct
    15181 tgtgtggcaa cttcgccaga aaccaggcaa acgggtagcc cagcaccagg caggcgaggg
    15241 tggcgatcag cgccatattc agcgagtgca atagcacttc aaaatagagc ggatcgagca
    15301 gacgcgtgta gttatccagc gtaaagacca ttttgacaaa actggcgtcg tcgcgggtca
    15361 aaaagctggt gccaatgatc atcaggttgg gcagaaagac aaacaacaca agccaaccga
    15421 caatagtgac aatcactaca ttctggaact tacttgtgtt cttcatcagc cagtacgacc
    15481 tcccagcttt ctacccaatt aatggccatt ttttggtcga gagagtggtc aaagtcagga
    15541 tcgtcttcat tgaagaattc gctgaccatc accatcttgc cattttccag ttcaacaacc
    15601 gactccagcg tcatgccttt gtagttacgc tcgcgaacgt aaccaatcag cccttcagcg
    15661 tggttgtcgt cgttaatctc ttcaacacgt aagtcttccg ggcgcagcag aacatgcagt
    15721 ttttgccccg gttcaacggc gaagttaacg tagatattac attcgcggcc ttcaacgttg
    15781 gcgcgtacgc gctgctcgtc tagacgttcg atgacagtgg cgttaaacat attgatttcg
    15841 ccaatgaagc cggcaacaaa caggtttttc ggctcttcgt agatttcacg cggcgtgccg
    15901 tcttgctcaa tgcgaccatc gcgcatcacc acaatcctgt ctgacatggt gagtgcttct
    15961 tcctggtcgt gagtcacaaa gacgaatgta atgccaagct tacgctgtaa cgctttcagc
    16021 tcgttctgca tttgcttacg cagtttgtaa tccagcgctg agagcgactc atccagcaac
    16081 aacagacgag gcttgttaac caccgcgcga gcaatggcga cgcgttgctg ttgaccacca
    16141 gagagctgat gcggtttgcg ttgagcgaag gtttccaact gcaccatccg cagggcttcc
    16201 atcacgcggg gcgtaatttc agcagcgggg gttttttgca tgcgcaaccc aaaggccaca
    16261 ttttcgaaca cggtcatgtg ggggaaaagt gcgtagcttt ggaaaacagt gttcacatag
    16321 cggttttccg ccggaacgtg ggtgatgtcc tcgttatcca gcatgatgcg tccggaatca
    16381 acagtttcca gacctgcaat caggcgaaga acggttgttt taccgcagcc agaagggcca
    16441 agcagcgtga ggaactcgcc attgttgata gtcagatcca gctggggaat gacctcttta
    16501 ccatcaaagc atttgcgaat tcccgccaat tgcaccagcg gtgaaagcga actcggttgt
    16561 ttattcaatt ttttactctg tcccatgtaa acgcaacgga tggcttaccg atgcggggtt
    16621 tgtggttaac caccttggtg actcttaatg agggcggtaa ttctacggca aaccgcttga
    16681 atcgccaatc tttgttgtga attactggct tagctttata ttcattaagg taatgctgat
    16741 aaatattccc gcttgcaggg gtaaaagtga cctgacgcaa tatttgtctt ttcttgcttc
    16801 ttaataatgt tgtcacaaaa agtgagggtg actacatgga taaactactt gagcgatttt
    16861 tgaactacgt gtctctggat acccaatcaa aagcaggggt gagacaggtt cccagcacgg
    16921 aaggccaatg gaagttattg catctgctga aagagcagct cgaagagatg gggcttatca
    16981 atgtgacctt aagtgagaag ggcactttga tggcgacgtt accggctaac gtccctggcg
    17041 atatcccggc gattggcttt atttctcatg tggatacctc accggattgc agcggcaaaa
    17101 atgtgaatcc gcaaattgtt gaaaactatc gcggtggcga tattgcgctg ggtatcggcg
    17161 atgaagtttt atcaccggtt atgttcccgg tgctgcatca gctactgggt cagacgctga
    17221 ttaccaccga tggtaaaacc ttgttaggtg ccgatgacaa agcaggtatt gcagaaatca
    17281 tgaccgcgct ggcggtattg caacagaaaa aaattccgca tggtgatatt cgcgtcgcct
    17341 ttaccccgga tgaagaagtg ggcaaagggg cgaaacattt tgatgttgac gccttcgatg
    17401 cccgctgggc ttacactgtt gatggtggtg gcgtaggcga actggagttt gaaaacttca
    17461 acgccgcgtc ggtcaatatc aaaattgtcg gtaacaatgt tcatccgggc acggcgaaag
    17521 gagtgatggt aaatgcgctg tcgctggcgg cacgtattca tgcggaagtt ccggcggatg
    17581 aaagcccgga aatgacagaa ggctatgaag gtttctatca tctggcgagc atgaaaggca
    17641 ccgttgaacg ggccgatatg cactacatca tccgtgattt cgaccgtaaa cagtttgaag
    17701 cgcgtaaacg taaaatgatg gagatcgcca aaaaagtggg caaagggtta catcctgatt
    17761 gctacattga actggtgatt gaagacagtt actacaatat gcgcgagaaa gtggttgagc
    17821 atccgcatat tctcgatatc gcccagcagg cgatgcgcga ttgcgatatt gaaccggaac
    17881 tgaaaccgat ccgcggtggt accgacggcg cgcagttgtc gtttatggga ttaccgtgcc
    17941 cgaacctgtt cactggcggt tacaactatc atggtaagca tgagtttgtg actctggaag
    18001 gtatggaaaa agcggtgcag gtgatcgtcc gtattgccga gttaacggcg caacggaagt
    18061 aagcgaaaag ggatgcggca tgtgatgccg catccggctt aaatccaaac ttacccttcg
    18121 aagaaccaat acccgctatt gaccagcgcc gcgagcatcg cgaggaatga cggatcttcc
    18181 agcgcatcgc caaaattctc cgcagtcagc gcaatgttgc tggcgagtgc atccagtgcc
    18241 ggacggtgcg gggaatcgat cttctcacca ttggcataca cgtcgtcgcc aatgcgcaat
    18301 acgcgcagac cacccaggcg caccagcact tcaccttgtt tcagcgcatc gtagatttca
    18361 tccggctgat aaggcggctc tggcggcgcg atatccagtt catgacgtga ctgggatata
    18421 aactcgccaa accattgctt aaagtgttcc ggctggttga tcaattcgag catcatctca
    18481 cgcagtttat ccatctcttg cggcagaaca tccgcaggat gagcgcgagg tggaacatcc
    18541 ggatcgctgt agtagttgcc gcccagttca cgttgcagca cataatcggc aaatccacta
    18601 atcagttccc gcgtatttgg cgcgcgaaag cccacggaat agttcatcgc attttccagc
    18661 gcgtagcctt catgcgggaa tcctggcgga atataaagaa tatcaccagg ctccagctct
    18721 tcatcgatga tggcttcgaa cggatcgacc tgtaacagat ccggatgtgg gcagtgctgt
    18781 ttcatttgca gcttttcgcc cactcgccag cgacgacgtc cggtaccctg aatgataaac
    18841 acgtcgtact gatcgagatg cgggccgacg ccgccgccgg gtacagaaaa agaaatcatc
    18901 agatcatcaa tacgccagtc cggtagttca cggaacggtc gcatcagcgc ggcggtcggc
    18961 tcatgccagt ggttcactgc ctgtaccagt aatgaccagt tggtttcacc gagatgatcg
    19021 tagctttcga acgggccgtg gctgacctgc catttgccat cctggtgact gaccagtcga
    19081 ctgtcaactt cgctttccat cgccagaccc gccaactcgt ctggagagat cgggtcaata
    19141 aaattattaa agccgcgttt taacaccacc gggcgtttct gccagtgacg ttcaagaaaa
    19201 tcgggccagt taagagtgag ttggtattcc atgttaagca tccacaggct ggtatctgca
    19261 accgattata acggatgctt aacgtaatgc gtgaagtatg ggcatattta ttcatctttc
    19321 ggcgcagaat gctggcgacc aaaaatcacc tccatccgcg caccgcccag catgctctct
    19381 ccggcgacga ttttaccctc atattgctcg gtgatttcgc gggctaccgc cagccctaca
    19441 ccttgcccag ggcgtaaagt atcaacccgt tgaccacggt cgaaaatgac ctctcgcttg
    19501 cttaatggaa taccggggcc atcatcctcg accacaatat agagatgctc gtcggtttgc
    19561 cttgcagaaa tttcgacaaa ctcgaggcaa tatttacagg cattatccag cacgttgccc
    19621 atcacctcga caaaatcgtt ctgctcaccg acaaagctga tctctggcga aatatcgaga
    19681 gagatattga cccctttgcg ttgatacact ttgttcagcg ctgaggtgag attgtccagc
    19741 agtggggcga ccggatgcag ctcgcggctg agcaatgtcc cgccgcgcat actggcacga
    19801 tgcaggtagt agccaatttg ctgtgaaatg cggctgattt gctccagcat taccggctca
    19861 gcatcactga cgctcatctt ttcactacgc agagaacgca gcgtactttg cagcaccgcc
    19921 agtggcgttt tcagactatg ggtcaggtcg gtgagcgtcg tacggtattt gtcgtaacgt
    19981 tcgcgttcac tttttaacaa tcggttcagg tttcgtacca gactggtcag ttctcgcgtt
    20041 gtggctggat tgagcaattc gcggttatgt tcttccagtt cgcggacttc ttttgccagg
    20101 gcttcgatgg ggcgtaaact ccaccaggcg gcgacccaca gcagcgggat cactaacagc
    20161 agattggctg agagcacata gataaaccag ctccagacca tataggaact ttttagctcc
    20221 accggaatgg tatccaccac cacaatggtt aattttggca tccgcgatgt tgccgggtag
    20281 acgtttactg ccaccgagtg ggtcatctcc gcgtcgtcat catcttcccg cacttcctgc
    20341 aactgttgct gtatcgaatg atctccactc agcaagaggc tggtatcgtt aacatccgct
    20401 tcaatttcat gaaaaccatt cgatttcagc cagtcaggct ggatcatctt catcagccag
    20461 ggcacgtcac gttgcgccca taaaagctgc ccgttctcat cataaattag cgtcatggtg
    20521 gggctttgct tgtcgatatt ttcgggtaac tcgacatgca acttattgtt ttcccacttc
    20581 gcaagggtat agaacagatt gctctcgcca cgtaacagcc gaaacgtagt tttatcgaaa
    20641 ctgacgctat aaccgatcag cgcgaccatt ccgtaggcaa gcgaaagcac cagtactacc
    20701 gctgccgttg ccaacagaaa acgtacccgc agcgagagcg ggaaaaaaag acgcagtaat
    20761 tttttcatca gcgcaattcg aacagatagc cctggccgcg aacggtggta atcacttctt
    20821 ggggatattg tgcctgaatt tttttgcgca gacgtcccat cagtacatca atggtatggc
    20881 tttcccgcag ctccgcatcc ggatagagtt ggagcattaa cgaatctttg ctgaccactt
    20941 tgccattatt gcgtatcaac gtttccataa tggtgtattc gaacgcggtc agtttgatca
    21001 cttcgtcatt aatagataat tcacggcgag agagatcaac ctgaaacggg gggagcgaaa
    21061 tgacctgtga agccagaccg ctattacgcc gcattaatgc ctgcattcgc gccatcacct
    21121 cttcaatatg aaacggttta gtcacataat catcagcacc ggcacttaat acttcgactt
    21181 tgtcctgcca gctttcacgg gcggttaata ccagaatcgg cagtgaaaca tcgttgctac
    21241 gccagcggcg aatcagtgac agaccgtcct cgtctggcaa tccgagatcg acaatcgcaa
    21301 tatccggtat atgttcattg agataataat cggcttcttt ggcatcttct gcgtcatcga
    21361 cctgatgacc agcatcctga atctgaactt taaggtggtg acgtaacaac gcattgtctt
    21421 caacaaccag tacgcgcatt tttatttctc cctgtcttaa ttattaaaat agtgtaacgc
    21481 gattatgtgg ttatgggggt aaacattaaa taaaccagcg gggaggggag gtaaagtgaa
    21541 aaaataaaaa gcggataatc ttaataagca ggccggacag catcgccatc cggcactgat
    21601 acgaggttta tttcagctca tcaaccatcg tgatagctcg accaatatag ttagccggcg
    21661 tcatcgcttt caggcgggct ttctcttctt ctggcaacgc cagaccatcg ataaactgct
    21721 tcatgccttc ggcgtcaacg cgcttaccgc gagtcagctc tttcagcttc tcgtacggtt
    21781 tttcgatgcc atagcgacgc ataactgtct ggattggttc agccagcact tcccagttgt
    21841 gatccagttc atccagcaga tggtcacggt tcacttccag tttgctcacg cctttcaggg
    21901 tggattgata tgcaatcaag gcataaccga tacccacgcc gaggttacgc agcacggtag
    21961 agtcggtcag gtcacgctgc cagcgggaaa ccggcagttt gcttgccaga tgctgcaata
    22021 ccgcgttgga aaggcccaga ttcccttcgg agttttcgaa gtcgatcggg ttaactttat
    22081 gcggcatggt ggaagaacca atctcaccag caatggtttt ctgtttgaag tggttaaggg
    22141 cgatataacc ccagacgtca cggtcaaagt cgatcagaat agtgttgaag cgcgcaacgc
    22201 aatcaaacag ttcggcaatg tagtcgtgcg gttcgatctg ggtggtgtac gggttccact
    22261 gaatacccag cgaggtgacg aactcttcgc tgaactgatg ccagtcaact tccgggtaag
    22321 cggcgatgtg ggcgttatag ttaccgaccg cgccgttgat tttgccgagg atctccacct
    22381 ggttaagctg gcggtactgg cgctccatac ggtaggcgac gtttgccatc tctttaccga
    22441 tggttgacgg cgtggctggc tgaccgtggg tacgagacag cagcgggata tcgcgatact
    22501 gaacggcgag atctttaatg ccatcaatca gttgacgcca gtatggcagg atcacttcat
    22561 cacgcgcggt tttcagcatt aatgcgtggg agaggttatt gatatcttcc gaagtacagg
    22621 caaagtggat gaattcagaa accgcgtgca gttccgggat ctccgccact ttttctttca
    22681 ggaaatactc aaccgcttta acgtcgtggt tagtggtacg ctcgatagtt ttgatgcgcg
    22741 ccgcatcttc ttcgctgaaa ctggcgacga ttgcatcaag gtaaccgatt gcgtcggcag
    22801 caaaagcagg aacttccttg atcgctgcgt gcgcggccag tttttgcagc caacgtactt
    22861 caacttgtac acggaatttc agcaaaccat attcgctgaa aatcccgcgc agcgcgctga
    22921 ctttatcgcc gtagcgtcca tcgacagggg aaacggcggt cagtgaggat aattccatag
    22981 atcacaactc cggggttaaa tgagcaagaa tttgttttgc ctgagtggtc aggcgattac
    23041 gagaaaacat cagttgcaga cgtccgccgc cgacctggtg ccagagcacg gcggcgcgaa
    23101 tgcctgccag cagggttgcg cgaactttcg cctgcacttg tgggctttgc agtacagcag
    23161 gggaaccggt gacctgaatg cgcgggccaa gcgggctaat cacatcaaca tagatagcag
    23221 ccatcgcgct catcagcgtt tcggactgta aatcgaagtg ttcgagctgg cgttgcaggc
    23281 cgttgatccg gttgcccaga gtgtcgagcg cgcctttcgc tgaggagagt ttgcgctcaa
    23341 gcaccatcaa gctgagtgtg tagcgggtta attcggcgtt taagccctgg cgactgctgg
    23401 cattgagcac gccgagcagg gtttccagcc cgacgcgcag gttggcttcg ctaccgccaa
    23461 aaaccgccag cgtcgagctg gggttcatat caataatact gttgagtgag acgtgtagcg
    23521 catcggcatc acaatgcccc tggtgagcga gttgttgcac caggcgtgcc gactgacaaa
    23581 taccggccag ggcgagggtg atgtcatagt aattctttgc cacgttcact gcttccttgt
    23641 tttaagtaaa gataataatc agaccggcag cggcagacgc tgctcaataa taccgccacc
    23701 gaggcacact tcaccgttat agaagacggc agactggccc ggcgtcacgg cggcaaccgg
    23761 ttcatcgaaa atcacttcaa tgcgatcatc gtccagcgcc ttgacggtgc aagggatatc
    23821 ggtctggcga tagcgggttt ttaccgtgca acgcatagtg ccggtgaatg gttcgcgatc
    23881 gacccagtgc aactgctggg caatcaaccc gacagacatc agccgcgggt gttcatggcc
    23941 ctgagcgaca accagaatgt tgttttcgac gtctttgtcc accacatacc acggttcttc
    24001 ggtaccttct ttggtgccac cgatacccag acctttacgc tgaccgagag tgtgatacat
    24061 cagcccctgg tgctcaccaa tttcatcgcc atcgacggta atgattttgc ccggttgcgc
    24121 cgggagataa cggcccagga actcgcggaa tttacgttcg ccaatgaagc aaatgccggt
    24181 agagtctttt ttcttcgcgg tgaccagacc aagatcttca gcaatcttac gcacctgcgg
    24241 tttttccagt tcgccgaccg ggaacaggct ttgcgcaatc tgctcatggc tgagcgtata
    24301 aaggaagtag ctctggtctt tattgctgtc cagaccacgc agcaggcggc tcttgccatc
    24361 gacatcggcc cgacgtacgt aatgaccggt agcgatataa tcggcaccta aatcttcggc
    24421 ggcaaattcg aggaaggctt taaatttgat ctctttgttg cacagaatat ccggattcgg
    24481 cgtgcgaccg gctttatatt cggcaaggaa cagttcgaag acgttgtccc agtactcggc
    24541 agcaaagtta acggtgtgca gttcaatgcc gagcttgtcg cagacagcct gggcatcagc
    24601 cagatccgct gccgctgtgc aatattcctc accgtcgtct tcttcccagt tcttcataaa
    24661 caggccttcg acctgatatc cctgttgttg caacagccag gcagaaacgg aggaatcgac
    24721 accgccggac atgccgacga ttactttttt tgcggtttca gacattggat cactcacgac
    24781 attgaacttc aaggcggcgt attctatcac gcagcctttt agatgacacc ctttgtaaaa
    24841 ggccagttaa aatcgccaat catctccagc ggataacgtt gcccgctttg ataacaacga
    24901 atactttccg ccaccagcgg cgaacgaaga tttgacgcct gtaaaatttc ttcggcgctg
    24961 acccaacggc agcagtcgat atcgctgtca tgaggctggg tcgggcatat ttgctcaagc
    25021 tcaatggcaa agaggaaacg caaaaacggc gttttatctg gcgcaatcca ctgatgcata
    25081 cgaataaagt gttgcggctg cgcgctgatg ccggtttctt cccacagttc acgggcggcg
    25141 gcttccacta aggtttcatc ggcttccaga tgcccggcag gttggttcca taacgcttta
    25201 ccattaatcg tctcttcaac gactaaaaat ttgccttctg cgtgcaccac gcaagcaacg
    25261 gtaacgtgcg gtttaaacat tttgcatcct taatctgtca cttctcgcca ttcaccattg
    25321 gcaagattat ccaaagagta atcacccatc gcatagcgaa tcagtcgcag cgtggggaag
    25381 ccaacatggg cggtcatgcg gcgcacctgg cgattacgtc cttcatataa ggtgatcttc
    25441 agccagctgg tgggaatact tttgcgttca cgaattggtg gattccgcgg ccataaccac
    25501 gcgggttcgt caaccagctc cgcgccggcg ggcagggtag ggccatcatt taaggttacg
    25561 ccattgcgca aggcttcaag tgcgtcttgt gtgggaatac cttccacctg cacataatag
    25621 atttttccgg tgcgtttacc cggctgggtt aaacgcgcct gcaacgcgcc gttattggtc
    25681 agcaccagca acccttcgct atcgcggtca aggcgacctg ctgcataaac accctgaacc
    25741 gggatgaatt cttttaatgt tttgcgtccg gcttcatcgg tgaactgcgg aagaacatcg
    25801 tagggtttat tgaacaggat cacacgcgtg ggctggtttt caggtttacg cctggtagaa
    25861 cgttgcgagc tgaatcgctt aacctggtga tttctaaaag aagttttttg catggtattt
    25921 tcagagatta tgaattgccg cattatagcc taataacgcg catctttcat gacggcaaac
    25981 aatagggtag tattgacaag ccaattacaa atcattaaca aaaaattgct ctaaagcatc
    26041 cgtatcgcag gacgcaaacg catatgcaac gtggtggcag acgagcaaac cagtagcgct
    26101 cgaaggagag gtgaatggaa agtaaagtag ttgttccggc acaaggcaag aagatcaccc
    26161 tgcaaaacgg caaactcaac gttcctgaaa atccgattat cccttacatt gaaggtgatg
    26221 gaatcggtgt agatgtaacc ccagccatgc tgaaagtggt cgacgctgca gtcgagaaag
    26281 cctataaagg cgagcgtaaa atctcctgga tggaaattta caccggtgaa aaatccacac
    26341 aggtttatgg tcaggacgtc tggctgcctg ctgaaactct tgatctgatt cgtgaatatc
    26401 gcgttgccat taaaggtccg ctgaccactc cggttggtgg cggtattcgc tctctgaacg
    26461 ttgccctgcg ccaggaactg gatctctaca tctgcctgcg tccggtacgt tactatcagg
    26521 gcactccaag cccggttaaa caccctgaac tgaccgatat ggttatcttc cgtgaaaact
    26581 cggaagacat ttatgcgggt atcgaatgga aagcagactc tgccgacgcc gagaaagtga
    26641 ttaaattcct gcgtgaagag atgggggtga agaaaattcg cttcccggaa cattgtggta
    26701 tcggtattaa gccgtgttcg gaagaaggca ccaaacgtct ggttcgtgca gcgatcgaat
    26761 acgcaattgc taacgatcgt gactctgtga ctctggtgca caaaggcaac atcatgaagt
    26821 tcaccgaagg agcgtttaaa gactggggct accagctggc gcgtgaagag tttggcggtg
    26881 aactgatcga cggtggcccg tggctgaaag ttaaaaaccc gaacactggc aaagagatcg
    26941 tcattaaaga cgtgattgct gatgcattcc tgcaacagat cctgctgcgt ccggctgaat
    27001 atgatgttat cgcctgtatg aacctgaacg gtgactacat ttctgacgcc ctggcagcgc
    27061 aggttggcgg tatcggtatc gcccctggtg caaacatcgg tgacgaatgc gccctgtttg
    27121 aagccaccca cggtactgcg ccgaaatatg ccggtcagga caaagtaaat cctggctcta
    27181 ttattctctc cgctgagatg atgctgcgcc atatgggttg gactgaagcg gctgacctga
    27241 ttgttaaagg tatggaaggc gcaatcaatg ccaagaccgt aacttatgac ttcgaacgtc
    27301 tgatggaagg cgctaagctg ctgaaatgtt cagagtttgg tgaagcgatc atcgaaaaca
    27361 tgtaatctct ccatgtgtta aatattgaaa cgggcgtata acacgcccgt tgttttattt
    27421 atgtggatat tattaatagc atatcgagca tatttatatg aagcccatta cttgagccca
    27481 tatgggcata tttttataat gcaactatta tgtaaacatt tatttgttat tttgctttct
    27541 cctggaggac actcttgact gcttttgagt aaactccata aatccttgtt gaatggtgcg
    27601 atgtgataaa tagtaatagg atattcttta tccttaagga taataccaga cttaaccggt
    27661 gtaaatatac tgccaggagg gagaaatata gtagattgat accagatgat cattttcata
    27721 ttaccccata tggctgaaaa agatatacca catgtaggtt gaattaccgt gtcaattact
    27781 atccacttca tttgttatgt cttatcccac ggt
//
LOCUS       DAPHKZ010000055        27432 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.055, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000055 DAPHKZ010000000
VERSION     DAPHKZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27432
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.055"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            200..505
                     /locus_tag="RH288_002455"
     CDS             200..505
                     /locus_tag="RH288_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine-rich inner membrane protein GfcA"
                     /protein_id="HDV4031502.1"
                     /translation="MKHKLSAILMAFMLTTPAAFAAPEATNGTEATTGTTGTTTTTTG
                     ATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTTR"
     gene            612..1256
                     /gene="gfcB"
                     /locus_tag="RH288_002456"
     CDS             612..1256
                     /gene="gfcB"
                     /locus_tag="RH288_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein GfcB"
                     /protein_id="HDV4031503.1"
                     /translation="MRPLILSIFALFLAGCTHSQQSMVDTFRASLFDNQDITVADQQI
                     QALPYSTMYLRLNEGQRIFVVLGYIEQEQSKWLSQDNAMLVTHNGRLLKTVKLNNNLL
                     EVTNSGQDPLRNALAIKDGSRWTRDILWSEDNHFRSATLSSTFSFAGLETLNIAGRNV
                     LCNVWQEEVTSTRPEKQWQNTFWVDSATGQVRQSRQMLGAGVIPVEMTFLKPAP"
     gene            1253..1999
                     /locus_tag="RH288_002457"
     CDS             1253..1999
                     /locus_tag="RH288_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HDV4031504.1"
                     /translation="MNKLQSYFIASVLYVMTPHAFAQGTVTIYLPGEQQTLSVGPVEN
                     VVQLVTQPQLRDRLWWPGALLTDSAAKAKALKDYQHVMAQLASWEAEADDDVAATIKS
                     VRQQLLNLNITGRLPVKLDPDFVRVDENSNPPLVGDYTLYTVQRPVTITLLGAVSGAG
                     QLPWQAGRSVTDYLQDHPRLAGADKNNVMVITPEGETVVAPVALWNKRHVEPPPGSQL
                     WLGFSAHVLPEKYADLNDQIVSVLTQRVPD"
     gene            1999..4095
                     /locus_tag="RH288_002458"
     CDS             1999..4095
                     /locus_tag="RH288_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HDV4031505.1"
                     /translation="MKKNSYLLSCLAIAVSSACHAEVLTYPDPLGSSQSDFGGTGLLQ
                     MPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLEGTIRYTDVRTRKYSQWEDFSGD
                     QSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMA
                     WGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPL
                     RLKLEYDGNNYQNDFAGKLPQASHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTN
                     FNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFDAPEIQLRDKTLYMS
                     GQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAG
                     TAPGQSEPLQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGL
                     MSSARYWFTDHLLLDGGIFTNIYNNYDKFKSSLLPADSTLPRVRTHIRDYVRNDVYLN
                     NLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDACWALGVDVNYVKQRDWD
                     NMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVG
                     VWAAISNVSKDDYGEGGFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRK
                     YQLYPMTAEREVPVGQ"
     gene            4141..5280
                     /locus_tag="RH288_002459"
     CDS             4141..5280
                     /locus_tag="RH288_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HDV4031506.1"
                     /translation="MKKNIFKFSVLTLAVLSLTACTLVPGQNLSTSNKDVIELPDNQY
                     DLDKMVNIYPVTPGLIDQLRAKPIMSQANPELEQQIANYEYRIGIGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNADGAIFYPYIGRLKVAGKTLTQVRNEITARLDSVIESPQ
                     VDVSVAAFRSQKAYVTGEVSKSGQQPITNIPLTIMDAINAAGGLTADADWRNVVLTQN
                     GVKTKVNLYALMQRGDLRQNKLLHPGDILFIPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TLAEALGNAEGMNQDVADATGIFVIRATQNKQNGKIANIYQLNAKDASAMILGTEFQL
                     EPYDIVYVTTAPLARWNRVISLLVPTISGVHDLTETSRWIQTWPN"
     gene            5268..5714
                     /gene="etp"
                     /locus_tag="RH288_002460"
                     /gene_synonym="yccY"
     CDS             5268..5714
                     /gene="etp"
                     /locus_tag="RH288_002460"
                     /gene_synonym="yccY"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine-phosphatase Etp"
                     /protein_id="HDV4031507.1"
                     /translation="MAQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGL
                     VKHPADATAADVAANHGVSLEGHAGRKLTAEMARNYDLILAMESEHIAQVTAIAPEVR
                     GKTMLFGQWLEQKEIPDPYRKSQDAFEHVYGMLERASQEWAKRLSR"
     gene            5734..7914
                     /gene="etk"
                     /locus_tag="RH288_002461"
     CDS             5734..7914
                     /gene="etk"
                     /locus_tag="RH288_002461"
                     /EC_number="2.7.10.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HDV4031508.1"
                     /translation="MTTKNMNTPPGSTQENEIDLLRLVGELWDHRKFIISVTALFTLI
                     AVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMIPNSSPESAPEIQLLQSRMILGK
                     TIAELNLRDIVEQKYFPIVGRGWARLTKEKPGELAISWMHIPQLNGQDQQLTLTVGEN
                     GHYTLEGEEFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQETF
                     TVSERSKESGMLELTMTGDDPQLITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQL
                     PEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQLNELTFREAEISQLY
                     KKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNR
                     QQELSISKSSAIGNVRIIDPAVTQPQPVKPKKALNVALGFILGLFISVGAVLARAMLR
                     RGVEAPEQLEEHGISVYATIPMSEWLDKRTRLRKKNLFSNQQRHRTKNIPFLAVDNPA
                     DSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQSDQKVLFI
                     DADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSEL
                     LMRDRMRQLLEWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVS
                     LSMQRLEQAGVNIKGAILNGVIKRASTAYSYGYNYYGYSYSEKE"
     gene            complement(8034..9332)
                     /gene="appA"
                     /locus_tag="RH288_002462"
     CDS             complement(8034..9332)
                     /gene="appA"
                     /locus_tag="RH288_002462"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acid phosphatase/4-phytase"
                     /protein_id="HDV4031509.1"
                     /translation="MKAILIPFLSLLIPLTPQSAFAQSEPELKLESVVIVSRHGVRAP
                     TKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQP
                     GQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNA
                     NVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSKLCLNRKKQDESCSLTQALPS
                     ELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQF
                     YLLQRTPEVARSRATPLLDLIMAALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGG
                     ALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNT
                     PPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL"
     gene            complement(9408..9500)
                     /gene="cbdX"
                     /locus_tag="RH288_002463"
     CDS             complement(9408..9500)
                     /gene="cbdX"
                     /locus_tag="RH288_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HDV4031510.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLDPRLKS"
     gene            complement(9513..10649)
                     /gene="appB"
                     /locus_tag="RH288_002464"
     CDS             complement(9513..10649)
                     /gene="appB"
                     /locus_tag="RH288_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDV4031511.1"
                     /translation="MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARDDD
                     ERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPL
                     AFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGT
                     FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGAIHLRSQLATKRAALLVMLCFLLA
                     GYWLWVGIDGFVLLAQDANGPSNPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPL
                     LTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQL
                     TLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY"
     gene            complement(10661..12205)
                     /gene="appC"
                     /locus_tag="RH288_002465"
     CDS             complement(10661..12205)
                     /gene="appC"
                     /locus_tag="RH288_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HDV4031512.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTG
                     KTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALM
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
                     IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALR
                     SFAIGSVFGTLAIIGTLQLGDSSAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPE
                     QDQERNAFAIKIPALLGILATHSLDKPVPGLKNLMAETYPRLQRGRMAWLLMQEISQG
                     NREPHVLQAFRELEGDLGYGMLLSRYAPDMNHVTAAQYQAAMRGAIPQVAPVFWSFRI
                     MVGCGSLLLLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDLLPTYSAHSALTTGQLAFSLIMIVGLYTLFLIAEVYLMQKYARLGPSAMQSEQ
                     PTQQQG"
     gene            complement(12339..13196)
                     /locus_tag="RH288_002466"
     CDS             complement(12339..13196)
                     /locus_tag="RH288_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HDV4031513.1"
                     /translation="MSETFFHLLGPGTQPNDDSFSMNPLPITCQVNDEPSMAALEQCA
                     HSPQVIALLNELQHQLSQRQPQLGEVLAVDLLNLNADDRHFINTLLGEGEVSVRIQQA
                     DDSESEIQEAIFCGLWRVRRRRGEKLLEDKLEAGCAPLALWQAATQNLLPTDSLLPPP
                     IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIG
                     YGESYINATGLRHVWHLRCTDTLKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVC
                     LWLAEAAPT"
     gene            complement(13193..13591)
                     /gene="hyaE"
                     /locus_tag="RH288_002467"
     CDS             complement(13193..13591)
                     /gene="hyaE"
                     /locus_tag="RH288_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HDV4031514.1"
                     /translation="MSNDTPFDALWQRMLARGWTPVSEFRLDDWLTQAPDGVVLLSSD
                     PKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTGGN
                     YRGVLSGIHPWAELINLMRGLVEPQQERAS"
     gene            complement(13588..14175)
                     /locus_tag="RH288_002468"
     CDS             complement(13588..14175)
                     /locus_tag="RH288_002468"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HDV4031515.1"
                     /translation="MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEYVEIVDG
                     GTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQSALAQLAAWGIVP
                     QPANESRCLNYDCLSMENYEGVRLRQYRMTQEEQG"
     gene            complement(14172..14879)
                     /gene="hyaC"
                     /locus_tag="RH288_002469"
     CDS             complement(14172..14879)
                     /gene="hyaC"
                     /locus_tag="RH288_002469"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HDV4031516.1"
                     /translation="MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLP
                     SVSGEATYLFYMGYIRLIHFSAGMIFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWW
                     QGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
                     APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMV
                     NGYRSHKFGKISNKERS"
     gene            complement(14898..16691)
                     /gene="hyaB"
                     /locus_tag="RH288_002470"
     CDS             complement(14898..16691)
                     /gene="hyaB"
                     /locus_tag="RH288_002470"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HDV4031517.1"
                     /translation="MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
                     GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVK
                     IHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMI
                     PDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNV
                     LPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQ
                     ERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLG
                     RILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAP
                     RGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELISVQVR"
     gene            complement(16688..17806)
                     /gene="hyaA"
                     /locus_tag="RH288_002471"
     CDS             complement(16688..17806)
                     /gene="hyaA"
                     /locus_tag="RH288_002471"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
                     /protein_id="HDV4031518.1"
                     /translation="MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAW
                     ALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAE
                     EVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
                     ASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVD
                     RMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACS
                     STRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGV
                     VAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA"
     gene            18233..18320
                     /locus_tag="RH288_002472"
     tRNA            18233..18320
                     /locus_tag="RH288_002472"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18267..18269,aa:Ser,seq:tga)
     gene            complement(18811..19341)
                     /locus_tag="RH288_002473"
     CDS             complement(18811..19341)
                     /locus_tag="RH288_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001164143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV4031519.1"
                     /translation="MQHLKNITAGNPKTVAQYQLTKNFDVIWLFSEDGRNWYEEVSNF
                     QKDTIKMAYDDNNIIVAITRDASTLNPAGLSVVEVADITANRRADDSGQWMYLDGQVR
                     KREYSSEEVNRQTEQRKATLLSEADAIIRLLERSVRLNMATEEERTRLSAWERYSVLL
                     SRVDSANPEWPQKPEQ"
     gene            complement(19345..21930)
                     /locus_tag="RH288_002474"
     CDS             complement(19345..21930)
                     /locus_tag="RH288_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HDV4031520.1"
                     /translation="MAVKISGVLKDGAGKPVQNCTIHLKAKRNSTTVVVNTVASENPD
                     EAGRYSMDVEYGQYAVILLVDGFPPSHAGTITVYEDSQPGTLNDFLGAMTEDDARPEA
                     LRRFELMVEEVARNASAVAQNTAAAKKSASDAGTSAREAATHATDAAGSARAASTSAG
                     QAASSAQSASSSAGTASAKAAEASKSAAAAESSKSAAATSAAAAKTSETNAAASQQSA
                     ATSASTATTKASEAATSARDAAASKEAAKSSETSAASSAGSAASSATAAGNSAKAAKT
                     SETNARSSETAAEQSASAAAGSETAAASSSREASVKAEEASASATAAGKSAESAASSA
                     SAATTKAGEATEQATAAARSASAARTSETNAKASETSAESSKTAAVSSASSAASSASS
                     ASASKDEAARLASEAQGSATTASAKATEAAGSATAAAQSKSTAESAATRAETAAKRAE
                     DIASAVALEDASTTKKGIVQLSSATNSTSESLAATPKAVKAACENAEKRLQKDKNGAD
                     VPDKDTFTKNIGACRAFGGAVSTTTGDWTTAQFIGWLESQGAFNHPYWMCKGSWSYGN
                     NKIITDTGCGNIHLAGAVIEVMGIKSAMTIRITTPTTSSGSGTANAQFTYINHGDGYS
                     PGWRRDYNTKNKPPAFALGKTGETLADTDAVAWNLDSGAYCAQDGGASSLILHFNTGE
                     GSCPAVQFRVNYRNGGIFYRSARDGYGFEADWERLFTTTGGTLDGAVGIGAQNTLGGH
                     SLALGRGDTGLKQNGDGNLDVYAGNARVMRFTNGSIQVSKGLNVSGRVNPSDYSNFDI
                     RYVRDIRLGTRVVQGMQKGVTYEKSGHVITGLCLVGDADGDNSAVYRPVQKYINGTWF
                     NVSQV"
     gene            complement(21989..25468)
                     /locus_tag="RH288_002475"
     CDS             complement(21989..25468)
                     /locus_tag="RH288_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HDV4031521.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPLDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVGNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQHCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGIRTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGQGSPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVAADDGRERLVSTARTTETTYRFTQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVETSARYLGTALYWIAASINIKPGHDYYFYVRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLTEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNDVFLKRLTAPTITSGGNP
                     PAFSLTPDGKLTAKNADISGNVNANSGTLNNVTINENCRVLGKLSANQIEGDLVKTVG
                     KAFPRDSRAPERWPSGTITVRVYDDQPFDRQIVIPAVAFSGARHEREHNDIYSSCRLI
                     VRKNGAEIYNRTALDNTLIYTGVIDMPAGRGHMTLEFSVSAWLVNDWYPTASISDLLV
                     VVMKKSTAGISIS"
     gene            complement(25528..26130)
                     /locus_tag="RH288_002476"
     CDS             complement(25528..26130)
                     /locus_tag="RH288_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HDV4031522.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALATQLPAFRQKLSD
                     GWYQIRIAGRDTGENELSARLNEPLANGAVIHIVPRLAGAKSGGVFQAVLGAAVMAVA
                     IWMPGVGIMASNLLFSLGASMTLGGVAQMLAPKPKTPRTQTTDNGKQNTYFSSLDNMV
                     AQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            complement(26067..26810)
                     /locus_tag="RH288_002477"
     CDS             complement(26067..26810)
                     /locus_tag="RH288_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4031523.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVSTPEGERYFPCMNISGEPE
                     GYFRMAPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGAIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHREDDWWRHGQNLYLDNMEAT
                     GFYRVALTEAQPGDVLLCSFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWHASAFTGICNDLAAASTFV"
     gene            complement(26815..>27432)
                     /locus_tag="RH288_002478"
     CDS             complement(26815..>27432)
                     /locus_tag="RH288_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDV4031524.1"
                     /translation="LTEVGGERYFFCNEQNEKGEPVTWQGRQYQPYPIQGSGFELNGK
                     GSAARPTLTVSNLYGMVTGMAEDLQSLVGGTVVRRKVYARFLDAVNFVNGNSDADPEQ
                     EVISRWCIEQCSELSAVSASFVLSTPTETDGAVFPGRIMLANTCTWTYRGDECGYHGP
                     AVADEYDQPTSDITKDKCSKCLSGCKFRNNVGNFGGFLSINKLSQ"
BASE COUNT         6318 a         7677 c         7041 g         6396 t
ORIGIN      
        1 tttatcttat gctcacaagt cgtatttcca gagggggata gttaacaatc ttatatttcc
       61 ctctgcgcgc ctttcctacc cgcagtatat agtgcaagcg gtatgaggaa agggagattt
      121 cacaaggatg ttatactcaa agtagacaat cctgatctca agcgtacgta ttgtccatgc
      181 gatgaataaa ggaaaagtta tgaaacacaa gctttctgca atccttatgg ccttcatgtt
      241 gacgacgcca gctgcgtttg ctgcccctga agcaacaaac gggaccgagg caacgacggg
      301 tactactggc accacaacga ccactaccgg cgcaaccacg actgctacta ccactggtgg
      361 cgtggctgct ggcgctgtcg gcacggcgac agttgtcggt gtggcaacgg ctgttggtgt
      421 ggcgacgttg gcagttgttg cagcaaatga cagtggcgat ggcggttctc ataacacctc
      481 aaccaccacg tccactacac gctaatactg ctttaacgcg tcgaaattaa agttaaatga
      541 tacccggttg cgatattcgt accgggcttt agagatttgc atttttttaa ttaacctttc
      601 aaggattaaa ggtgcgccct cttattttat cgattttcgc actatttctt gcgggatgta
      661 cgcacagcca gcaaagtatg gtcgatacat ttcgcgccag ccttttcgat aatcaggata
      721 tcaccgtagc ggatcagcag atccaggcgt tgccttattc cactatgtat ttacgcctta
      781 atgaagggca acgaatcttt gtggtactgg gatatataga acaagaacaa agcaaatggt
      841 tatcccagga taacgccatg ctggttaccc acaatggacg tcttttaaaa accgtcaaac
      901 ttaataataa tctgctggaa gtgacaaatt ccgggcagga ccctctgcgt aacgcgctgg
      961 caataaaaga tggcagccgc tggacgcgcg atattctctg gagtgaagac aaccattttc
     1021 gctctgcgac cctgagttct actttttcct ttgctggatt agagacgctg aatattgcgg
     1081 gtcgcaatgt gctgtgtaat gtctggcagg aagaggtgac ttccacgcgg ccagaaaaac
     1141 agtggcaaaa cacattctgg gtcgattcgg ctactggcca ggttcgtcaa agtcggcaaa
     1201 tgttaggcgc aggggttatt cccgtagaaa tgacgtttct taaacccgca ccatgaataa
     1261 attacagtcg tatttcattg ccagcgtact ttacgtaatg acaccccatg cctttgcgca
     1321 aggaacggtg actatttatc tgcctggcga acaacagaca ctttccgttg gccccgtgga
     1381 aaatgttgtc cagttggtga cacaaccgca actgcgcgat cgcctctggt ggcctggtgc
     1441 cttgctgacc gactctgcgg cgaaagctaa agcgcttaaa gactaccaac atgtcatggc
     1501 acagcttgct tcctgggaag cagaagctga cgacgatgtg gcggcaacga ttaaatccgt
     1561 gcgccagcag ttactcaatc tcaatatcac tggtcgctta ccggtcaaac tggaccctga
     1621 ttttgtacga gtggatgaga acagcaatcc cccgttggtc ggggactata cgctctatac
     1681 cgtacagcgt ccggtgacta ttactctgct gggtgcggtt tctggggccg ggcaattgcc
     1741 ctggcaggca ggccgtagcg ttaccgatta tctgcaagat cacccccgcc ttgcaggcgc
     1801 ggacaagaat aacgttatgg tgattacgcc tgagggtgag actgtcgtcg cccctgttgc
     1861 cctgtggaat aaaagacatg tggaaccacc gcctggcagc cagctttggt tgggcttttc
     1921 tgcgcatgta ctgcccgaaa aatatgctga tttaaatgac cagattgtgt ctgttttaac
     1981 gcaacgtgtt cctgactgat gaagaagaat tcttatcttt taagctgcct ggccattgcc
     2041 gtctccagtg cctgtcatgc tgaagtatta acctacccgg atccgctggg ttcgtcgcaa
     2101 tcagactttg gcggcacagg attgttgcag atgccaaatg cgcgcatcgc accggaaggt
     2161 gaattcagcg tcaactaccg ggataacgat caataccggt tctactccac ctccgtggcg
     2221 ctgttcccat ggctggaagg caccattcgt tatacggatg tgcgcacacg caaatatagc
     2281 cagtgggaag atttcagcgg cgatcagtca tacaaagaca aatcattcga ttttaaactt
     2341 cgcctgtggg aagaaggtta ctggctaccg caagtggcgt ttggtaaacg tgatattgct
     2401 ggtacgggtc tgtttgacgg tgagtatctg gtggccagca agcaagcggg gccatttgat
     2461 ttcaccctcg ggatggcatg gggctacgcc ggtaatgcgg gcaatattac caacccgttt
     2521 tgccgggtga gcgataaata ttgtcatcgc gcagagtctc acgatgcggg cgatatcagc
     2581 tttagcgata tctttcgtgg cccggcttcc atctttggcg gcattgagta tcaaacgccg
     2641 tggaatcccc tgcgtctgaa actcgaatac gatggaaaca attaccagaa tgatttcgct
     2701 ggcaaactgc ctcaggcaag ccatttcaac gtcggcgcag tttatcgcgc tgccagctgg
     2761 gcagatctca acctgagtta tgaacgcggt aacacgttga tgtttggctt cacgttacgg
     2821 accaatttca acgatctgcg ccctgccctg cgcgatacgc caaaaccggc atatcaacct
     2881 gcgcctgaat ctgaaggatt gcagtacacc acggtagcaa accaacttac cgccctgaag
     2941 tataacgcgg gctttgacgc gccagaaatt cagctacgcg ataagacact gtatatgtct
     3001 ggtcagcaat acaaataccg tgactctcgt gaagcggtcg atcgtgccaa ccggattctg
     3061 gtgaataacc tgccgcaagg cgttgagaag attagcgtga cgcaaaagcg cgagcatatg
     3121 gcgatggtga ctaccgaaac cgacgtagcc agcctgcgca aacagctggc aggtacagcg
     3181 cctggtcaat cagagccact gcaacaacaa cgtgttgaag ctgaagatct ttctgccttt
     3241 ggtcggggct accgtattcg tgaagatcgc tttagctact ctttcaaccc aacactttca
     3301 cagtcgctgg gcggcccgga agatttctat atgttccagc tggggctgat gtccagtgcc
     3361 cgctactggt ttaccgacca cctgctgctt gatggcggta ttttcaccaa tatttacaac
     3421 aactacgaca agtttaagtc ttcgctgttg cccgcggact ctaccctgcc ccgcgtgcgc
     3481 acgcatatcc gtgactacgt tcgcaatgac gtttatctca acaacttgca ggcgaactat
     3541 tttgctgact taggcaatgg tttctatggc caggtgtatg gcggttatct ggaaacgatg
     3601 tacgccggtg tcggttccga gctgctttat cgcccgctag atgcctgctg ggcgctgggt
     3661 gtggacgtta actacgtgaa gcaacgtgac tgggacaaca tgatgcgttt caccgattat
     3721 tccacgccaa caggtttcgt gacggcttac tggaacccgc cgacgctcaa tggcgtactg
     3781 atgaaactta gcgttgggca atatctggca aaagataaag gcgcaacgat cgacgtcgcc
     3841 aaacgctttg acagcggcgt ggcggtaggg gtatgggcgg caatcagtaa cgtatctaaa
     3901 gatgactacg gcgaaggcgg ctttagtaaa ggtttttata tctcgattcc attcgacttg
     3961 atgaccattg gacctaaccg caaccgcgcg gtggtttcgt ggacaccatt gacgcgtgat
     4021 ggtggacaaa tgctgtcacg caaataccag ctctatccaa tgacggcaga gcgagaagta
     4081 ccggttggac aataacctga cgtaattcat aacattacat tgactgataa atataaacca
     4141 atgaaaaaga acatttttaa gttttcggta ctgacattgg ctgttctgtc tttgacagca
     4201 tgtacccttg ttcctggtca gaatttatcg accagtaaca aggatgtcat tgaactacct
     4261 gacaatcagt atgacctgga caaaatggtc aatatctatc ccgtcacgcc aggattgatt
     4321 gatcagttgc gcgccaaacc gattatgtcg caggctaacc cggagctgga gcagcaaatc
     4381 gcaaactatg aatatcgtat cgggattggt gatgtgttga tggttacggt ctgggatcac
     4441 ccggaactaa ccacccccgc agggcaatac cgtagcgcca gtgataccgg caactgggtt
     4501 aacgccgatg gtgcgatttt ctacccctat attggtcgcc tgaaagtggc cgggaaaaca
     4561 cttacccagg tacgcaacga gattacagcg cgtctcgatt cagtcattga aagcccgcaa
     4621 gtcgatgtca gcgtcgcggc gttccgatcg caaaaagcgt acgtcaccgg cgaagtcagc
     4681 aaatcgggtc agcagccgat taccaatatt cctctgacca tcatggatgc gattaacgcc
     4741 gcgggcggtc tgaccgcaga tgcagactgg cgcaacgtgg tgctcaccca gaatggcgta
     4801 aagaccaaag tgaacctcta tgcgctgatg cagcgtggcg acttgcgcca gaacaaactg
     4861 ctgcacccgg gcgatatttt atttattccg cgcaacgatg atctgaaagt cttcgtgatg
     4921 ggtgaagtgg gtaaacagag cacgctgaaa atggaccgca gcggtatgac cctggcggaa
     4981 gcgctgggta acgctgaggg tatgaatcag gatgtcgctg atgcgacggg gatttttgtt
     5041 attcgtgcaa cgcaaaacaa gcagaatgga aaaatcgcca atatttatca gctgaatgcg
     5101 aaggacgcat cggcaatgat actcggaacg gaattccagc ttgaacctta cgacattgtt
     5161 tatgtcacta ccgcgccgct ggctcgttgg aaccgtgtga tttctctgct ggtaccgacg
     5221 atttccgggg tgcatgacct gacagagact tcacggtgga ttcaaacatg gcccaactaa
     5281 aatttaactc aatcctggtg gtttgtaccg gcaacatttg ccgttcgccc attggcgagc
     5341 gcttgctgcg taaacgtctg ccgggcgtaa aagtcaaatc ggcaggtgtt catggtctgg
     5401 taaaacaccc tgcagatgcg acagcggcag atgttgccgc taatcatggc gtatctcttg
     5461 aaggacatgc cggacgtaag ctcactgctg agatggcacg aaattacgat ctgattctgg
     5521 caatggagtc ggaacatatt gctcaggtta ccgcaatcgc tcccgaggtc cgcgggaaga
     5581 caatgctgtt tgggcaatgg ctggaacaga aagagatccc ggatccctat cgtaaaagtc
     5641 aggacgcatt tgaacatgtc tacggtatgt tggagcgcgc cagtcaggaa tgggcgaagc
     5701 gcctcagccg gtaatttgag tttataaaat acgatgacaa ctaaaaatat gaatacgcca
     5761 ccaggcagca ctcaggaaaa tgagatcgat ctgcttcgtc tggtcggcga gttatgggat
     5821 caccgtaagt ttattatcag cgtgaccgcg ttattcacgc tgatcgctgt cgcttactcg
     5881 ctgttaagca caccaattta tcaggcagat actctggtcc aggttgagca aaaacagggc
     5941 aacgccattc tcagcggcct gagcgatatg atccctaact catcgcccga gtctgcaccg
     6001 gagatccaac tgctgcaatc gcgcatgatt ctcggtaaaa ccattgctga actgaatctg
     6061 cgcgacatag ttgagcagaa gtattttccg attgtgggtc gcggctgggc gagattaacc
     6121 aaagaaaaac caggtgagct ggcgatcagc tggatgcata ttccacaact gaatggtcag
     6181 gatcagcaac tgacactcac ggttggggaa aacggccact atacactgga aggtgaagag
     6241 ttcaccgtca atggtatggt cggccagcgt ctggaaaaag atggcgttgc gctgactatc
     6301 gcggacatta aggccaaacc aggaacacag tttgtcctga gccagcgtac cgaactggaa
     6361 gcgattaacg cgttgcagga aacctttacc gttagcgaac gcagtaaaga aagcgggatg
     6421 ctggaactta ccatgactgg tgatgatccc cagttgatta ctcgtattct gaacagcatc
     6481 gctaacaact atttgcaaca gaatatcgct cgccaggcgg cgcaggattc acaaagcctt
     6541 gaattcttac agcgccagtt gccagaagtg cgcagcgagc tggaccaggc ggaagaaaaa
     6601 ctcaacgttt atcgccagca gcgcgattcg gttgacctta acctggaagc caaagccgtt
     6661 cttgagcaga ttgttaacgt tgataatcaa ctcaatgagc tgaccttccg cgaggcagag
     6721 atctcccagc tgtataagaa agatcaccca acttatcgtg cgctgctgga aaaacgccag
     6781 acgctggagc aagaacgcaa acgcctgaat aagcgggtat cggctatgcc ttccacccaa
     6841 caggaagtgt tgcgtttaag tcgtgacgta gaagcgggcc gtgcggtata tctgcaatta
     6901 cttaaccgcc agcaggagtt gagtatttcg aaatccagtg ccattggtaa cgtgcggatt
     6961 atcgacccgg cagtcactca gccgcagcca gtgaaaccga aaaaagcgtt gaacgtggcg
     7021 cttggtttta ttcttggcct gtttatttcg gtgggtgccg tgctggcgcg tgcgatgttg
     7081 cgtcgtggtg tagaagcacc ggaacaactg gaagagcacg gcatcagcgt ttatgccact
     7141 atcccaatgt ccgagtggct ggataaacgc acccgtctgc gtaagaaaaa tttattttct
     7201 aatcagcagc gccatcgtac taaaaatatc cccttcctgg cggtggataa cccggcggat
     7261 tctgctgtgg aagccgtacg tgcgctacga accagtctgc atttcgctat gatggagact
     7321 gagaataaca ttctgatgat caccggtgcg acgccagaca gtggtaaaac atttgtcagt
     7381 tcaactctgg cagcggtgat cgcccagtcc gatcaaaaag tgttatttat tgatgccgac
     7441 ttacgccgtg gttattcgca taacctgttt accgtgagta atgaacatgg cttgtcggaa
     7501 tatctggcag gtaaagatga gctcaacaaa gtgatccagc attttggcaa aggaggcttt
     7561 gatgtgatta ctcgcggtca ggtgccacct aacccgtctg aactgctgat gcgcgatcgg
     7621 atgcgtcaat tactggaatg ggcgaacgac cattacgatc tggtgattgt cgatacgccg
     7681 ccgatgctgg cggtgagcga tgctgcggtc gtggggcgct ctgtcggcac cagcctgctg
     7741 gttgcgcgtt ttggcctgaa caccgccaaa gaggtgagct tgtcaatgca gcgtctggaa
     7801 caggcaggcg tcaatattaa aggcgcaatc ctcaatggtg tgattaaacg cgccagcacc
     7861 gcttacagtt acggctataa ctattacggt tatagttact ccgagaaaga gtaaaactga
     7921 aggtaaagtg accggatgcg gcgtgaacgc cttttccggt ctacgcatta gacagttctt
     7981 cgtttgtcat cagcctcaga gcattcaggt aactgaatgc tcttttttat gcattacaaa
     8041 ctgcacgccg gtatgcgtgc ttcattcacg atttgcgtaa aacctgccaa cgaacacatg
     8101 ccctgcgcat ttcgctcttc acatcctgcc agggtcagtt tcacctctcc gggcggcgta
     8161 tttaatgaca gcggcgtttt atcacgcatc tgctgtaaag tctggaagac cagcgaaacc
     8221 tgaatccact ggctgttatc gcttagccga cgccagcgtt caaacaccag ttcaccacct
     8281 ggcggcgtgt tatccggctg acctggaagc gtccagttga gctccagtgc gccgccgaga
     8341 tttgccagat tagtatcgtg tccggcaata aacagcactg aagtgggtaa tgtcacacca
     8401 tacgcctgtt tttgcggtgg atggggcgtc aacgctgcca tgatcaaatc caataacggg
     8461 gtggcgcgac tgcgggcaac ctctggcgtg cgttgtagta aataaaattg cgcgttatgc
     8521 aaacttagca aggtgttcca ctggtgtgaa tcagtgatcc ttccccaccc cggctccggc
     8581 attccctgtg cttgttgcag gagaaatatt tccgtcagca ttgatgcgag gcttaccgca
     8641 ccggttaatg agacattgtc ggcgctcacc ttgagttccg atggtaatgc ctgcgttaat
     8701 gaacagcttt cgtcctgttt cttacggtta aggcacaatt ttgattgcgg aaaattaagc
     8761 acccgttcca gttcgcgaaa cgccgtttgc cgatgcccgg taaagtcagc aattgaccct
     8821 cctgccctgc tgaggatcgc gtcagtcacg ttcgcgttat ccagttggca aacgccagtt
     8881 tttagaggat taaataacgg atcgggactg gacgtatctg cctgggtatg tacggttatt
     8941 gcacagtcag gtgccagccc ggcggcgaag gcttcgcctg ttttacgggt acgctcgtcg
     9001 acatcagcaa taatcgcgac ctgaccaggc tgcgggcagc cctttttcgc cagcaatccg
     9061 tcggctacca gacgctggcg ttggtaatgt ccgagatagg cgattagctc accaccgcgc
     9121 ggtgtcagcc aacccagttt taccggccag gttggccatg cgtctggggt gacatcctgc
     9181 atcagttgcg tggccttggt tggtgcacgc acaccatgac gactgacaat caccacactt
     9241 tccagcttca gctccggctc actctgagcg aatgcagatt gcggggttaa cggaatcaaa
     9301 agagataaaa atgggattaa gatcgctttc atcgatatgt ttccgctttt catatccgac
     9361 attattgcct gatgcgacgc taatgcgccg catcaggctt acgttcgtta acttttcaat
     9421 cgcgggtcca gccataccaa cacaagggtg gagagcgaac acatcaacaa aatgccgacg
     9481 aaccaaagta aataccacat tgttcctgct ccttagtaca gctcgttttc gttacggcgg
     9541 agagtttctg tcgtcatgcg tccccacatt ttgtagtagc tccagagagt gtagagcaac
     9601 acaatgggca aaaatatcag cacgattacc aacataatgc tcagcgtcag ctgactggaa
     9661 gtgctgtccc acaacgtcag gctggagatt ggactcacgc ttgacggcat gacaaagggg
     9721 aacagcgtga tgcctgccgt gaaaatcacg ccaaattgca tcaatgacgc cattaaaaat
     9781 ccccaacccg ggcgaccacg ataaatcgcc atcaccgtca gcaatgggca gaagaacccc
     9841 agcagcggga agatccacaa aacgggcgat tcgacgaaat tattcatcca ggcaccaggt
     9901 agcactgcca ccagtttcat taacggattg gaaggaccgt tagcatcctg ggcgagcagt
     9961 acaaagccat caataccgac ccacagccag taacccgcca gcaaaaagca cagcatcacc
    10021 agtagtgcag cgcgtttggt cgccagctgt gaacgcagat gaatcgcacc aacagttttc
    10081 agttgtaacc agacgccacc ttgcaaaatc accatcccaa ggctgagtaa tccgcacaat
    10141 aaagggaatg gcgtcagcag ttgccagaag gtgccgagat actccacgcg taattgcggt
    10201 gtgaaggcaa acggcacgcc gagcagcaag ttgccgaagg cgataccgaa gactaccggc
    10261 ggcaccagac tgccgatgac cagaccggca tcccacattt tacgccagcg tgcatcggca
    10321 atttttccgc gataatcaaa ggccagcgga cggaagaaca gcgagcacag caccaggatc
    10381 atcgccacat aaaagccgga aaacgccgct gcatacactc tgggccaggc agcaaataat
    10441 gccccacctg cgaggatcaa ccagacctga ttgccttccc agtgcgcacc aacgctatta
    10501 atcactatcc ggcgttcatc atcatcacgc gccaccagcg gcagcaaaca gccaatcccc
    10561 atgtcaaatc cgtcggagat cataaagacc accaggatca cgccaatcag cagccaccag
    10621 atgaagcgca atgtttcata atcaaacatg attttctcct ttacccctgt tgctgcgtcg
    10681 gttgttcact ctgcatcgcg ctcggcccca gacgggcata tttctgcatc aggtagactt
    10741 cggcgattaa gaacagggtg taaagcccta cgatcatgat cagtgagaaa gccagttgtc
    10801 ctgtggttaa agcggagtgc gcggagtatg tcggtaagag gtcctgtatc gcccacggct
    10861 gacgaccaaa ctcggtcata aaccacccgg cttcaatcgc aatccacggc aacggcaaac
    10921 tccagagcgc cattttcagc acccagcgat gctggtcgat tttgccacgc agcgtctgga
    10981 caagcgcaat aagcatcacc agtagcagca gggaaccaca gcccaccatg atgcggaaac
    11041 tccagaatac cggcgcaacc tgaggtatcg cgccacgcat cgccgcctgg tactgtgcgg
    11101 ctgtgacatg attcatatcc ggcgcatagc gggagagcaa catgccgtag cccaggtcac
    11161 cttccagttc ccggaatgcc tgcaacacat gcggctcacg attgccttgc gatatttcct
    11221 gcattaacag ccaggccata cgtccgcgtt gcaagcgtgg gtaggtttca gccatcaaat
    11281 tcttcagacc cggcacgggt ttatctaatg agtgagtggc gaggatccct aacagcgcgg
    11341 gaattttgat ggcaaaggcg ttacgctctt gatcctgttc cggccaggca accacatgga
    11401 acggtgcagg agcaggttcc gtttgccact ccccttccat cgccgccagt tttaccggtt
    11461 gtacttgcgc gacttcatac gcagaactgt ctccgagttg cagggtaccg ataatcgcca
    11521 gagtaccgaa gacggaaccg atggcaaacg agcgtaatgc gacatcgcgc tcccgtccgc
    11581 gcagtaaata ccaggcgctg atcgccataa taaacatggc cccggtcacg tagcccgcca
    11641 ttacggtgtg cacaaatttc acctggctga ccgggttaaa gaccagctcg ctgaagctgg
    11701 tcatctccat acgcagggtg tcgatatcaa aatgcgcacc ggtcgggtat tgcatccaac
    11761 cgttggcatt caatatccac aatgcagaga gatttgaacc gaacgccacc agccacgtca
    11821 ccagcaggtg ctggtattta ttcagccgct gccagccgaa gaagaacagc ccgacaaagg
    11881 tggattcgag gaagaaggcc attaatgctt ccatcgccag cggtgcgcca aaaatatcgc
    11941 ccacatagtt ggaataaaat gaccagttag taccaaactg aaactccatg gtcaggccgg
    12001 tagccacgcc aagagcaaag ttgataccga agagcttacc ccagaagcgc gtcatatcgc
    12061 ggtagattgt tttgccggtg accacgtaaa tggtttccat gatagccagc aaaaaaatca
    12121 gccccagggt aaggggtaca aataaaaagt gatacagcgc ggtcagagca aactgccagc
    12181 gcgataaatc aatgacatcc cacatgcgca ctcctgtagg cgaagagaga aaaataaccc
    12241 gataatggta gatctccctc tttatcctga aactctacga ccagaggtat tcgccgattg
    12301 cgatattcat aagactgaaa gcgatactta ccgtcttttt acgtcggtgc agcttccgcc
    12361 agccacagac atacctcgct aagccgctgc gcagagtcga ccaaatcttc tggcgctgcc
    12421 agcaccactt ccggtattgg gcagatttca taactttcca gtaaagggcc ttttaaggtg
    12481 tccgtacagc gtaaatgcca gacatggcgt aaccccgtgg cgttgatata gctctcgcca
    12541 tagccaatgg tacgaatctg aatatttccc ggcccacaga gacgtgagag aaaaagccga
    12601 tcagcctcgc tgatgggtaa ttgcgtcaga ttaatgctgt gcggctgcgc gtcggggtta
    12661 cgtacatgtg ccagtaactc atgcgccaac ggtaggccat tcatcaggcc atcaatgggc
    12721 ggcggtaaca gcgaatctgt cggcaagaga ttttgcgttg ccgcctgcca caacgccagc
    12781 ggcgcgcagc cagcctccag tttgtcctcc agcaactttt cgccgcgacg tctgcgcacc
    12841 cgccataatc cgcagaagat cgcctcctgt atttcacttt cgctgtcgtc agcctgctga
    12901 atgcgcactg acacttcccc ttccccgaga agcgtattga taaagtgacg atcgtcggcg
    12961 ttgagattta acagatcgac tgccagcacc tcgcccaact gcggctggcg ttgacttagt
    13021 tgatgttgta actcgtttaa cagcgcaatc acctgcgggc tgtgagcaca ttgctccaag
    13081 gccgccatac tcggttcatc attcacctga caggtgatcg gcagtggatt catgctgaaa
    13141 ctgtcatcgt tcggttgcgt tcctggcccc agcagatgga aaaaagtttc gctcatgagg
    13201 cacgctcctg ttgtggttcg acaagcccac gcatcaggtt tatcagttcc gcccacgggt
    13261 gaataccact cagcacgccg cgatagtttc cgccggtaaa cactaatgtg gcgggaaagc
    13321 gaaagacgcc aaagcgatct ccgatggctt cgctctgttc aaggtcagca atcgccacct
    13381 gccatgtgta gtcgggaaac tcgcgcagta attcgccaat cattaccgga ttatcgctga
    13441 cctctggcgt gcgtttcggg tcactgctta ataacaccac gccgtctggc gcttgcgtaa
    13501 gccagtcgtc aagacggaat tcactaaccg gcgtccagcc gcgcgccagc attcgttgcc
    13561 acaacgcatc aaatggcgtg tcgttgctca tccctgctcc tcctgtgtca tccggtactg
    13621 gcgcaagcga acgccttcgt aattttccat cgacagacag tcataattga gacaacgcga
    13681 ttcattagcc ggttgcggca caattcccca cgcagccaac tgcgccagcg ccgattgttc
    13741 cgcagcgggc agttgctccc gtgccagttc gctcaggctg ccgccgtagt cgtcgagcat
    13801 cgcgggttgc agaccgacga gggcaatatg tgctggcaga tgtccgcgga tatctgccag
    13861 cgccagcact tcggagaaac tgttctggtg caggctcatt ttcttcgcgc tgagataagc
    13921 cggaatgcgt tctccggcat acgttcgtag cgttccgggt tccagcccgt aatcaatggc
    13981 atcgagaatc aacagatgac tggcgctttc gacatacccc agcaagttca gtccctgagt
    14041 accgccatcg acaatctcca catactcggg ccagtggtaa tgggcataca gccgttccgc
    14101 cacccgcacg ccgaagcctt catcggccca cagcaggttg cccagcccca ttaccaccac
    14161 gcgttgctcg ctcatgaacg ctccttgtta cttattttgc caaatttgtg gctacggtag
    14221 ccgttgacca tggtggagat caccgtgtcg tcggacatga tgtcttcacg cagcgccatg
    14281 tagacatgac cgatcacaaa cgcgccaatc agccacatcc ccagccgatg ccagctgtga
    14341 atgtccattg agttgccacc cgtccagtag aaaaattcca ccacataacg gaacggcgca
    14401 aaaatagcgt actggctgtg ttcgctgtac agcgcaaaac cggtgatgat cataaagacc
    14461 gacatcagga aatagccgaa catcgccgcc tgggcgatgg ggttatggcc tatatcggca
    14521 ctcggacgtt ttgccagaaa cagataccag cggatttcat accacacgcc ctgccaccag
    14581 cttttacgcc ataccggcac gataaacagc tcgcgggagt aacgattgcc aacaaaagcc
    14641 cagtagatcc gcatcagcaa gaccacggta aaaatcatcc cggcgctgaa gtgaattaac
    14701 ctgatgtaac ccatatagaa cagatacgtc gcctcgccac tgacggaagg tagcggcttg
    14761 ccgataaagt atccggtgac catcaacacc gccatgcata acaccgtcaa ccagtgccag
    14821 atgcgcactg gcgcttcaaa gacatagtgg ctgacaacgt tgtcgctttt ctgttgcatg
    14881 atgattctcc ttcgctgtta acgcacctgc acggagatca gctcgctacc gtcgtcgccc
    14941 agcacgtgtg ttgaacaggc gaggcacggg tcaaagctgt gcagagtacg caggatctcc
    15001 agcggttgct cggggatcgc cattttggtg ttcatcagcg ccgcttcata agcgccaatc
    15061 tgccctttgg gatcgcgcgg gctggcgttc caggtggtcg gcaccacgca ctggtagaga
    15121 tcaatcttgc catcgcgaat ggcggcccag tggcctaacg ccccgcgcgg cgcttcggta
    15181 aaaccgacac cacggcactc tgtcggccag gttgcaggtt cccatttttc cgtggaagca
    15241 gtggcgagat tgccgttttt caggttggtc atcagcttgt cgaagaaata ctgcaactta
    15301 cctgcggccc actgcgcttc gtgcgcgcgg cacaaaatgc ggcctaacgt tgactggata
    15361 ccggaaagcg gcaggttcaa cgccgacatc atgcgatcga ccgactcaac ggtcgcagca
    15421 tcgcctttgt gataagcgat taacgtgcgc gccagcggcc ccacttccat cgcgttaccg
    15481 cgccagcgtg gcgctttgat ccacgagtag cgttcctgtt cattcagctg ctgaatgttg
    15541 gtatcgctgc ctttgacatc gccggggttg taccacgggt cggtgatgcc atcgaacgga
    15601 tgacgcccga cctgatcgtt gggatatcga taccaggcgt ggtcgacaaa ctcctgcacc
    15661 tgctgcggat caaccaaatc cactggcagc acattgttga agtcgccgtt aatcaccgcg
    15721 ccgccaggca tcagcagact tttctcgcca aagtcgttgg caatatccgg gaatgcgccg
    15781 tagctgagaa cgcatttatc agaaagacca gtgccgattt cgctccacgg tttgttgaac
    15841 tgaccgatgg ctaaggcgtc ggggatcatc acgttgttaa tgaagtccgc cgtgcgggtg
    15901 ataattgact gcaccaggtt caggcgttcc atattgactg ccccgaccgc gccgctttcg
    15961 tcaatgttga tggcgcaagg catcccgccg acaatccagt ttggatgcgg gtttttaccg
    16021 ccaaagaccg cgtggatttt gacaatttca cgctggaaat cgagagcttc gagatagtgg
    16081 gcaaagccca tcaggttagc ttctggcggc agtttgtact gcgggtgccc ccagtagcca
    16141 ttgcggaaga tccccaactg cccgccttca acaaattttt tcaggcggtt ttgtacgtcg
    16201 aagaaatagc caggggatga tttcggccaa gaggagagac tttgcgccag ttcggaggtt
    16261 ttccgcgggt cggctttcag cgcatctaac acatcgatcc agtccatccc ggcaagctga
    16321 tagaagtgca ccagatgatc gtggcaccag agcgttgcca gcataatgtt gcggatgata
    16381 ttggcgttgt ccggcacttt aataccgata gcatcttcga tggcgtaaac cgaagccagg
    16441 gcgtgtacgc cagtacagac gccgcagata cgttcaacga acgcccacgc atcgcgcggg
    16501 tcgcgccctt gtaggatgat ctccagcccg cgaaacatgg tgccgcagga gacggcattg
    16561 gtgatcacat tctgatcgtt aatattcact tcgcagcgca tgtggccttc gatgcgcgta
    16621 atcgggtcga ccaccaggcg gcgtccggca ttattgatgg tgtatccctg agtttcgtac
    16681 tgagtgctca tgcctgttta tcctcattgc ctggctgatg ttcggtttct gtaggttgct
    16741 ggttatgacg tctgcgctgg tcaacggcgc tggcgactgc gtgcacacca acagccgctg
    16801 ccaccacgcc aagcgcggtt aaaccgacgg tatcggcggt ggaatgagta cccatttgcg
    16861 gaatatcgac cacgcggctg tagaacgaac cgcgatccca gaaaccattt tccgcacagc
    16921 ccaggcagcc gtgaccagac tggattggga aagaaacgcc atcattccag cgtgtggagg
    16981 aacaggcgtt ataggtggta ggccctttgc agcccatttt gtacaggcag taacctttgc
    17041 gggcagcgtc atcatcccaa ctctggacga actctccggc gtcgaagtgg gcgcggcgat
    17101 agcatttatc gtggattcgc tgaccataga acatcagcgg acggcccatt ctgtcgacat
    17161 ctggcaagcg atcaaaggtc accatgtaag taatgatggc gctcatcaca tccgggatcg
    17221 gcgggcagcc aggtactttg ataatgggtt tgtcggtgat gactttgtcg ataggcgttg
    17281 cctgcgtcgg attgggtcgc gcggcctgca cgcagcccca ggacgcgcag gttccccagg
    17341 cgataatcgc gctggctccg gcagcggcac gtttgagttt ctcaataaac ggtcgaccgc
    17401 tgctgataca gaacatcccc tgctcgccca gcggcggatt accttctact gcgaggatat
    17461 atttgccatt gtattgcgtg atgatgtctt caaagacttc ttccgcctgg gttccggcgg
    17521 cagccatcaa agtatcgtcg taatcgaggg aaatcaggga aaggatgacg tccttcgcca
    17581 gtgggtgagc ggagcggata aaagattcgg tacagcaggt gcattccaga ccgtggatcc
    17641 ataccaccgg aatgcgcggt ttgttctcca gcgcccaggc aatctttggt gccattcccg
    17701 cgcctaatcc cagcgacgtg gcagccagac tacaatattt gagaaagctg cgccgggtaa
    17761 cgccctgacg ccgcatggcc tggtaaaatg tttcctcgtt attcatatcg cacgtctctc
    17821 ctccttgcga caccggcagg acaccgggcg cttatggtcg gcaagcgacg tccctgtagc
    17881 aaggcaaacc atcgcttcac gtgagatgct gaaaacgaaa gctcatcctt ctgcactggc
    17941 gcacgtcgcc agaaagtatt gttaataaag cgtagtgaaa cttttgcaca aaacaataca
    18001 aactgtgtgg atttatcttt tagcgataaa aatggaccta tttttctttt ggccgggcgg
    18061 tggggatgtt tagccggttg ctaaacgagt aaaagagaag gaattcatgg tgatgaaatg
    18121 atcaatctgc tgttatttca cgctatcaat gcacttttgg ctgtttttca ggcaaacaaa
    18181 caaattaggg gtttacacgc cgcatcggga tgtttatagt gcgcgtcatt ccggaagtgt
    18241 ggccgagcgg ttgaaggcac cggtcttgaa aaccggcgac ccgaaagggt tccagagttc
    18301 gaatctctgc gcttccgcca aataatcaag gggttaccaa atggtagccc ctttgctttt
    18361 tgggctcttg gtataaactt ggtataccaa ttggtatatt ttctgccaaa aaattcctaa
    18421 aatcccctcc agcacaaaca atcacttgct cattcatact tatcaagaaa atatccttgc
    18481 aagttatgtt gtttctttct gcgtcccgac agggtgtcat ggttccccac ttctctcggg
    18541 atggacactt aacggacgag aaattttcag gtgtcattca gacgcgcttc ggccccggat
    18601 tggcgaagcg cgcttttttt ctcagattat ttcgttttgc ctgagtgttg aataacgcca
    18661 ctacagttat ataagctgga aatcattcaa tactcgcact atcgaaagtt caccagccaa
    18721 ccgcagcaca ttcctgcata cgacgtgtct gcggcttttt tcatctctgc ctgtaattac
    18781 tgattaacgt aaaatcctct tccccgatat ttactgctct ggcttttgtg gccattccgg
    18841 gttcgctgaa tccacccggc tgagcaggac gctgtaacgc tcccatgccg acagccgggt
    18901 tcgctcttct tccgtagcca tattcagcct tactgaccgc tccagaagcc ggatgatggc
    18961 atctgcttca ctgagcagcg tggccttgcg ttgctctgtc tgtctgttga cttcctctga
    19021 cgaatactca cgtttcctca cctgaccgtc cagatacatc cactgccccg aatcgtctgc
    19081 acggcggttc gccgttatat ctgccacctc aacaacactt aatcccgccg gattaagcgt
    19141 tgaggcatcc cgggtgatgg caacgataat attgttatca tcgtaagcca tctttattgt
    19201 gtctttctga aagttactca cttcttcata ccagtttctt ccgtcctctg aaaacaacca
    19261 gataacatca aaattttttg tcagttgata ctgagcaacg gttttgggat tacctgctgt
    19321 aatatttttt aagtgctgca ttacttatac ctgcgatacg ttaaaccatg tgccgtttat
    19381 gtatttttgc accggccggt aaaccgctga gttatcgcca tcagcatccc cgacaagaca
    19441 aagccccgta atgacatggc cggatttctc atacgtcacg cctttttgca tgccctgaac
    19501 aacacgcgta cccagccgga tatccctgac atagcggata tcaaaattac tgtaatcgga
    19561 aggattaacg cgcccggaca cattcagccc tttactgacc tgaatgctgc cgtttgtaaa
    19621 gcgcattaca cgtgcgttac cggcgtaaac atcaagatta ccgtcgccgt tttgtttcag
    19681 gcctgtgtcg cccctcccca gcgcaagtga atgaccgccc agcgtattct gtgcaccgat
    19741 acccaccgcg ccatccaggg tcccgcccgt tgtcgtgaac agacgctccc agtccgcctc
    19801 aaagccatag ccatcacggg cggagcggta aaatatcccg ccatttcggt aattcacccg
    19861 aaactggacc gcagggcagc tgccttcccc tgtattaaaa tgaagaatta aggatgatgc
    19921 gccaccatcc tgtgcacaat aagcgccact gtccaggttc caggcgacag catctgtatc
    19981 ggcgagcgtt tccccggttt ttcccagcgc aaaggccggt ggcttgtttt tcgtgttgta
    20041 gtcacgacgc cagccagggg aataaccatc accatgatta atataggtaa actgcgcatt
    20101 cgccgttcca cttccgctgg atgttgtcgg tgtggttatg cggatcgtca tcgctgactt
    20161 tatccccatc acctcaatga cagcgccggc gagatgaata tttccgcagc ccgtatccgt
    20221 gatgatttta ttattaccgt aagaccagga gcccttgcac atccagtatg ggtggttaaa
    20281 tgcgccctga gactccagcc acccgataaa ctgtgcggtc gtccagtctc ctgtcgttgt
    20341 gcttacggcc ccaccgaaag cacggcaggc accaatattt ttcgtaaagg tgtctttgtc
    20401 ggggacatcc gcaccgttct tatctttctg cagtcgtttc tcagcattct cacaggcggc
    20461 ttttactgcc tttggtgttg ccgccagtga ctcggaagtg ctgttggttg cactgctgag
    20521 ctggactatc ccctttttcg tcgtgctcgc atcctcaagc gccacggcag acgcaatatc
    20581 ctccgcccgt tttgccgcag tctcagcgcg cgttgccgcg gattctgccg tgcttttgct
    20641 ctgtgctgcc gctgtcgcac tgccagctgc ctctgtcgcc ttcgcggatg ccgtcgtggc
    20701 actgccctgc gcctctgacg ccagccttgc cgcctcatct tttgaagctg acgccgatga
    20761 tgctgatgac gccgccgaac tggcggacga tacggctgcc gtttttgagg attctgcgct
    20821 ggtttccgac gctttcgcgt tcgtctcgga tgtcctcgca gcggaagcag acctcgctgc
    20881 tgcagtggcc tgttcagtgg cttcgccagc cttcgttgtg gctgctgaag cggacgatgc
    20941 ggcgctttct gccgattttc cggcggcggt ggcactggct gaggcctcct ccgctttaac
    21001 tgacgcctca cgggacgatg atgcagcggc agtttctgag cctgctgctg cggaggcact
    21061 ctgttccgct gccgtttcag aagacctggc gttcgtctca gacgtctttg ccgccttcgc
    21121 ggaatttcct gccgccgttg ccgaggaagc tgcgctaccg gcgctcgagg ctgcgctcgt
    21181 ttctgatgat tttgccgcct cttttgaggc cgccgcatcc ctggctgacg tggcagcttc
    21241 tgacgctttc gtggtcgcag tggatgcaga cgtggcggct gattgttgtg acgctgccgc
    21301 attcgtttct gacgtttttg ccgcagcggc actggtggcc gccgcgcttt ttgaggactc
    21361 tgcagcggca gcactttttg atgcctcagc ggcctttgct gatgccgttc ctgcgctgga
    21421 agacgctgac tgagccgacg aagcggcctg tccggctgac gtgctggctg cgcgtgctga
    21481 gcctgcagca tcagtcgcat gggttgccgc ctcacgggct gatgtaccgg catcgctggc
    21541 ggattttttc gcagctgccg tgttctgtgc cactgcggac gcgttacgcg ccacctcttc
    21601 caccattagt tcaaaacggc gcagtgcctc cggacgggca tcatcctccg tcatggcacc
    21661 gagaaaatca ttcagtgtac cgggttgaga atcttcatac acggtgatgg tcccggcatg
    21721 tgacggcggg aaaccgtcaa ccagcaggat aacagcgtac tggccatact caacatccat
    21781 actgtaacgc ccggcttcat ccggattttc tgaggccacc gtgttcacca ccaccgtggt
    21841 actgttacgt tttgctttca gatgaatggt gcagttctgt accggtttac ctgcaccgtc
    21901 tttcagcacg cctgaaatct ttactgccat attcgttcca caaataaaaa aggtgccatt
    21961 tctggcaccc ggtctggttt ctgaacattc agctgatact gataccggct gtggatttct
    22021 tcatcaccac aaccagcaaa tcgctgatgc ttgccgtggg ataccagtca ttcaccagcc
    22081 acgctgatac cgaaaactcc agcgtcatgt gaccgcgacc cgctggcata tcaatcacac
    22141 ctgtataaat cagcgtatta tccagcgcgg tacggttata aatttcagca ccgtttttcc
    22201 gcactatcag acggcatgat gaataaatgt cattatgctc tctctcatgt ctggcaccgc
    22261 tgaatgccac cgccggaatg acaatttgcc ggtcaaaagg ctgatcgtca taaaccctga
    22321 cggtgatggt ccctgatggc caccgttccg gtgcacggga gtcccggggg aaagctttgc
    22381 ccactgtttt aacgagatcg ccttcaatct ggttggcgga caattttccc agaacccgac
    22441 agttctcgtt aatcgtgacg ttgttgagcg tcccggagtt cgcattcacg ttaccgctga
    22501 tatcggcatt tttagcagtc agctttccgt ccggtgtcag ggaaaaggcc gggggattgc
    22561 cgccgctggt aatggtgggg gccgtcaggc gcttcaggaa cacgtcgttc atgaatatct
    22621 gatcgccctg accaacaaac atcggttttg tgttgccatt tgcaggatta atcatcgcaa
    22681 tcctgtccgc cgccagcagc acctgactct gcatgccgtc aggggtgttc tcaataccgg
    22741 caccgatacc cgcaatataa aggcgtccgt cctgcatctg ctgcagcttc actgcccaca
    22801 tgctgttcag gttattattt gtatcaacct gaaccttctg tatctgctgg atcgctgcac
    22861 tctggtcttc cagtttctta ttgacggtct gtgttatttc attgctgaca tccgttatgg
    22921 acgtcctgat ttcagtcagg tcaggcgcaa gctgaccgtt atcaatctgc gtccacagct
    22981 cctgagccag atgggttttc cctatctcgc ctttgaaaaa atccagatag cctgatgcat
    23041 catcactcgg ctgaccgaca gcctccacga atgccgattt gccaacggtg ttcacactgc
    23101 gaacgtaaaa ataataatca tggcccggtt tgatattgat actggcggct atccagtaca
    23161 gtgccgtacc aagataacgc gcgctggttt caacctgcct gatatccgca atccgttttt
    23221 ccgagaacca gaactcaaac tgtaccgtcg ggtcataaac cgcaagatgc ggcgtggcgg
    23281 ttatctgaaa atagcccggc gtcagctcaa tccgcgacgg cgctgccggt gcggcaatcc
    23341 ggaacgatac cgacgccgga tcgccctgct gcccccacgc atttactgcc cggactgtca
    23401 gcctgtagtt ccccagagcc agttgtgtga agcggtaagt ggtttccgtc gtccgggccg
    23461 tgctgaccag ccgctcacgg ccgtcatccg ctgccacggt caggcgaagc aggaagctca
    23521 cgcccttcac caccttcggc gtgtcccagc gcgccagcac ctggtattcc ccgctgtctg
    23581 cggtgacttc tgcggtcagg tgctgcaccg ctggcggcgt gacaccattt accgtgccgc
    23641 tctggtcgcc gtcaaagtgc gccccgttat ccacgatggc ctctttttcc ggtacatgct
    23701 gcacggcggt gatggcatac gtgccgtcgt cgttctcacg gatactcacg cagcggaaca
    23761 ggcgctggcg caacgtcggc agcttcagcc cccatacgct gtattcagca acgccgtcag
    23821 gaacacggct cactttcacc ttcacgccgt cggtgacgga ctgaacctcc acgctgaccg
    23881 gactcccctg cccgtcaacc aggcttatca gcgtggtgcc ggaagatggc agcgtgattt
    23941 cacggtcgag cgtcagcgtc cgggtctggc tgtttaccgc cagcacgcgt ccgccggtgc
    24001 ggataccggc atagtcatca tcgcagattt caatgacatc gcccggtaca tggcgaagcc
    24061 cttcggcacc cacgctgaag tccacggtct gcgtttccag cagttctgtt ttaatcagcc
    24121 acagcccggc gcggtgtgcc tgcccccggc tggtacagcc aaaagcatcc atcttcgtga
    24181 cgttacgacc gtaacgggca atggcctgcg tgtcctccac aagctctgtc gccgtctccc
    24241 agccgttatt cgggtcaatc cagttcacct caacggcatt atggcggtcc ttcagggcgc
    24301 tgaagctgta gcggaacggc gcaccatcat ccggcatcac cacattactg cggttatagg
    24361 tccacacctt atccgacggt cggtcctgca cgaacgtcag cgtctgcccg ttccataccg
    24421 gcatacagcg catcgcagag cagaaatcac tgagcacatc ccacgccttg cgctgtgtgg
    24481 tcaggtacgc attacaggtg atgcgcggct ccgtgccgcc aaaaccgtcc ggcaccgact
    24541 gatcgcaatg ctggccgatg acatacagcg cccatttgtc cacatccgcc gcaccaagac
    24601 gtttccccat gccgtagcgc ggatgggtca gcatatccca cagacaccag gccatgttgt
    24661 tgctgtatgc tggcttaaac gttccgtccc agataccgct gtattgccgc gtctgcgggt
    24721 tatagttcga cggcacctgc agaatgcgcc cgcgcagatg ataattacgg ctcacctgct
    24781 ggctgccgaa ctgctccgaa tccacctgca cgccgaccag tgccgtgttc gggtagcact
    24841 gtttcacatc gatgatttcg gtgtatgacg accagagcgt tttgttctgc agctggtctg
    24901 tggtgctgtc cggcgtcatc ctgcgcatcc gtatattgaa cgggcgcggc ggcaggttac
    24961 ccaccaccac cgaggccaga tactgcgagg tggttttgcc cttaatggtg atgtcttttt
    25021 ccgtcaccca gccaccatta cgctggatct gaaccagcag gcggacttcc gacggattcc
    25081 ggtccccctt tgaggtggtt tccaccagtg cctgcacgcc gaaggtaaaa cgcagacggt
    25141 cgatgtttgc cgacgtgatg gtccgggtga tcggcgtgtc gtatttcact tccgtaccca
    25201 gcaccgtctc ggagccggag gattcaaatc cctccggcgg tgtctgctcc tgctcaccgg
    25261 cccggaacac caccgtgacg ccggagatat tggtattccc ctcactgtcc agcactggcg
    25321 tactgttcag cagcacgctt tttaatccat ccaacggacc ttcaaccggc ccttcgctga
    25381 tggcatcgat cacactcagc aactgcgtgg acttcagatt gtccttcgct tcgcgcggag
    25441 tatgcccctt actgctgcct ttacccattc ctcacgctcc ataaacgaca aaaccgcccg
    25501 gaggcggttt cacataaacg tttttcatca gcgaccaatc accacaacct gaccaccatc
    25561 cccttcgtct gccgtgctga tctcctgaga gaccacccgc gaccccacgc gcatttcacc
    25621 gtacagaacg ggcagaacat tgccctgggc aaccatatta tccagtgaag aaaaataggt
    25681 gttctgtttg ccgttatccg ttgtctgtgt gcggggggtt ttgggtttag gggccagcat
    25741 ctgtgcaaca ccgccaagcg tcatactggc accgagagaa aacagcagat tactcgccat
    25801 aattcctacc cccggcatcc atatagcaac cgccataaca gccgccccca gcacagcctg
    25861 aaacacaccg ccacttttgg ctcctgccag acgcggcacg atgtggatca cagcaccatt
    25921 tgccagcggt tcattaagac gggctgataa ttcgttttca cctgtatcac gcccggcaat
    25981 ccgtatctga taccagccat cgctcagttt ctgacgaaac gccgggagct gtgtggccag
    26041 cgcccggatg gcttcagccc ccgttttcac acgaaggtcg atgcggcggc caaatcgttg
    26101 caaatccccg taaaggcaga tgcgtgccat gcccggtgac gccagaggga gtgtgtgcgt
    26161 cgctgccatt tgtcggtgta cctctctcgt ttactcagtt gttcaggaat atggtgcagc
    26221 agctcaccgt caccacagta aatggcagca tgattcggca ccgatgaacc aaagctgcac
    26281 agcagcacgt cgccaggctg cgcctctgtc agtgcgacac ggtaaaaacc cgttgcctcc
    26341 atattgtcaa gatagagatt ctgaccgtga cgccaccagt catcctcgcg atgaaaatcc
    26401 ggcatctcaa tccccgccag atgataagca tcccggaaca gcgtgtaaca gtccgtcacc
    26461 ccgtgctcaa agcgacgccc ggtgagatgc ggcacacagc ggaacttgtg aatcgccccc
    26521 cggcagacca gccaccacgg caaatcactc tgcacctgca gccgccggtc agcctcactc
    26581 agccagggca gaccaccggg atgactgtgg accagtgcca caatctcacc ctgcatctct
    26641 gcctgcagcc agtcctccgg agccatccgg aaataaccct ccggctcacc ggaaatattc
    26701 atgcagggaa aatatctttc cccctccggc gtgcttacca cgaagccgca cgactccgct
    26761 ggcgcacatc gccgggcgtg cgccagaatc gctgattctg tttctgtcat gggtttactg
    26821 cgaaagtttg ttaatggaaa ggaagccgcc aaagttgccg acgttattgc gaaacttaca
    26881 gccactcagg catttgctgc atttatcttt cgtgatatcg gatgttggct ggtcatattc
    26941 atccgcgaca gccggaccgt gataaccgca ctcatcaccg cgataggtcc aggtgcaggt
    27001 gttggccagc atgatacgtc ccggaaaaac agcgccgtcc gtttccgtcg gcgtggacag
    27061 tacaaaagag gcactcaccg cgctcagttc gctgcactgc tcaatgcacc agcggctgat
    27121 cacctcctgc tccggatcgg cgtcactgtt tccgttgacg aagttcaccg catccagaaa
    27181 acgggcgtaa accttacgcc ggaccaccgt tccgccaacc agactctgca gatcttccgc
    27241 catcccggtg accatgccgt acaggttaga gaccgtcagt gtcggacggg cagcactgcc
    27301 cttgccgttc agttcaaaac cgctcccctg aatgggatac ggctgatact gtcgcccctg
    27361 ccaggtgacc ggctcacctt tttcgttctg ctcattacag aaaaaataac gttctccacc
    27421 gacctctgtc ag
//
LOCUS       DAPHKZ010000056        26900 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.056, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000056 DAPHKZ010000000
VERSION     DAPHKZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26900
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.056"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            66..797
                     /gene="artJ"
                     /locus_tag="RH288_002479"
     CDS             66..797
                     /gene="artJ"
                     /locus_tag="RH288_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein ArtJ"
                     /protein_id="HDV4031525.1"
                     /translation="MKKLVLAALLASFTFGASAAEKINFGVSATYPPFESIGANNEIV
                     GFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTT
                     PYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKISDQWFPQ"
     gene            complement(996..2123)
                     /gene="rlmC"
                     /locus_tag="RH288_002480"
     CDS             complement(996..2123)
                     /gene="rlmC"
                     /locus_tag="RH288_002480"
                     /EC_number="2.1.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HDV4031526.1"
                     /translation="MQCALYDAGRCRSCQWITQPIPEQLSAKTADLKNLLADFPVVEW
                     CAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALK
                     PFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSDTKLAQLRKALPWLHE
                     QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVA
                     SQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIASEAIACAKQSAA
                     ELGLTRLQFQALDSTQFATAQGDVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSC
                     NAQTMAKDIRELPGFRIERVQLFDMFPHTAHYEVLTLLVKQ"
     gene            complement(2164..2652)
                     /locus_tag="RH288_002481"
     CDS             complement(2164..2652)
                     /locus_tag="RH288_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HDV4031527.1"
                     /translation="MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIF
                     NTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEIWCAFSLVKGRRWARWLYLLTQI
                     TAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
                     LQ"
     gene            complement(2712..3557)
                     /gene="potI"
                     /locus_tag="RH288_002482"
     CDS             complement(2712..3557)
                     /gene="potI"
                     /locus_tag="RH288_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HDV4031528.1"
                     /translation="MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELLRDDAMMSAVGLSLTIAACAATAAAILGTIAAVVLVRFGRFRGSNGF
                     AFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
                     SRLRELDSSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQ
                     RARRG"
     gene            complement(3554..4507)
                     /gene="potH"
                     /locus_tag="RH288_002483"
     CDS             complement(3554..4507)
                     /gene="potH"
                     /locus_tag="RH288_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HDV4031529.1"
                     /translation="MNTLEPAAQSKPPGGFKLWLSQLQMKHGRKLVIALPYIWLILLF
                     LLPFLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQS
                     LQVAAISTFCCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
                     NGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAA
                     LDLGARPLKTFFNVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ
                     EFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG"
     gene            complement(4517..5650)
                     /gene="potG"
                     /locus_tag="RH288_002484"
     CDS             complement(4517..5650)
                     /gene="potG"
                     /locus_tag="RH288_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HDV4031530.1"
                     /translation="MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERQEDGLVLDSPGLV
                     HPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEVIHIAYLGDLSVYHV
                     RLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV"
     gene            complement(5745..6857)
                     /gene="potF"
                     /locus_tag="RH288_002485"
     CDS             complement(5745..6857)
                     /gene="potF"
                     /locus_tag="RH288_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HDV4031531.1"
                     /translation="MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
                     DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDICVAIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKAATPLVSAEVRENPG
                     IYPPADVRANLFTLKVQDPKIDRVRTRAWTKVKSGK"
     gene            complement(7208..7684)
                     /locus_tag="RH288_002486"
     CDS             complement(7208..7684)
                     /locus_tag="RH288_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HDV4031532.1"
                     /translation="MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVF
                     DAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH"
     gene            complement(7772..8674)
                     /gene="rimK"
                     /locus_tag="RH288_002487"
     CDS             complement(7772..8674)
                     /gene="rimK"
                     /locus_tag="RH288_002487"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HDV4031533.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLR
                     SMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGG
                     AASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGI
                     DIAGKMIRWIERHATTEYCLKTGG"
     gene            complement(8735..9457)
                     /gene="nfsA"
                     /locus_tag="RH288_002488"
     CDS             complement(8735..9457)
                     /gene="nfsA"
                     /locus_tag="RH288_002488"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HDV4031534.1"
                     /translation="MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQ
                     CSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP
                     ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRR
                     TIIKESRPFILDYLHKQGWATR"
     gene            complement(9441..9728)
                     /locus_tag="RH288_002489"
     CDS             complement(9441..9728)
                     /locus_tag="RH288_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1418 family protein"
                     /protein_id="HDV4031535.1"
                     /translation="MRAIGKLPKGVLILEFIGMMLLAVALLSVSDSLSLPEPFSRPEV
                     QILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNRPPQYSRSEREKDNDANH"
     gene            9888..10145
                     /gene="grxA"
                     /locus_tag="RH288_002490"
     CDS             9888..10145
                     /gene="grxA"
                     /locus_tag="RH288_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 1"
                     /protein_id="HDV4031536.1"
                     /translation="MQTVIFGRSGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGIT
                     KEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA"
     gene            complement(10175..10552)
                     /locus_tag="RH288_002491"
     CDS             complement(10175..10552)
                     /locus_tag="RH288_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HDV4031537.1"
                     /translation="MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLF
                     FILPGAVASFFSQRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFW
                     CALGALCFLFISSLFKPQHRKNQ"
     gene            10822..12507
                     /locus_tag="RH288_002492"
     CDS             10822..12507
                     /locus_tag="RH288_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HDV4031538.1"
                     /translation="MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVI
                     GLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLM
                     VFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG"
     gene            complement(12682..13218)
                     /gene="rcdA"
                     /locus_tag="RH288_002493"
     CDS             complement(12682..13218)
                     /gene="rcdA"
                     /locus_tag="RH288_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RcdA"
                     /protein_id="HDV4031539.1"
                     /translation="MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGS
                     MTYYFSGIDELLLEAFSSFTEIMSRQYQAFFSDVSDAPGACQAITDMIYSSQVATPDN
                     MELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
                     RKPLSREEILRMVERVAG"
     gene            13302..14510
                     /locus_tag="RH288_002494"
     CDS             13302..14510
                     /locus_tag="RH288_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4031540.1"
                     /translation="MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     SIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTMSCALIGMMILSLALWLTS
                     PLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
                     LTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGVPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMLVVLALVILAAIVAKAVAKPD
                     TKTQTAMENS"
     gene            14510..15325
                     /gene="ybjI"
                     /locus_tag="RH288_002495"
     CDS             14510..15325
                     /gene="ybjI"
                     /locus_tag="RH288_002495"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415365.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase"
                     /protein_id="HDV4031541.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVAS
                     GNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFATVVEHLLTRPEV
                     EIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
                     VQKALHEAIGDIMVSVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGN
                     DIEMLRQAGFSFAMENAGNAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFDQ"
     gene            15411..15695
                     /locus_tag="RH288_002496"
     CDS             15411..15695
                     /locus_tag="RH288_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031542.1"
                     /translation="MFMKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSV
                     PQAVSVATVPQTVYVAPAPAPAYRPHPYVRHLASVGEGMVIEHQIDDHHH"
     gene            complement(15736..16968)
                     /gene="mdfA"
                     /locus_tag="RH288_002497"
     CDS             complement(15736..16968)
                     /gene="mdfA"
                     /locus_tag="RH288_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdfA"
                     /protein_id="HDV4031543.1"
                     /translation="MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLA
                     QNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKN
                     GRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLA
                     RLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGL
                     VRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWL
                     SLMVIFLKDKQMGNSHEG"
     gene            17253..17849
                     /gene="ybjG"
                     /locus_tag="RH288_002498"
     CDS             17253..17849
                     /gene="ybjG"
                     /locus_tag="RH288_002498"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDV4031544.1"
                     /translation="MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAVV
                     LWLWGLTAQRQLVIKIAIALAVSLFVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFP
                     SDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
                     CLSAQIIWQAMGHKLYQRLQSWYRVCFALPIRKGWVRD"
     gene            17907..18665
                     /gene="deoR"
                     /locus_tag="RH288_002499"
     CDS             17907..18665
                     /gene="deoR"
                     /locus_tag="RH288_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HDV4031545.1"
                     /translation="METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNN
                     HSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKLAATLVEPDQTLFFDCGT
                     TTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
                     LNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPA
                     RMGDLKRFDIVVSDCCPEDEYVKYAQTQRIKLMY"
     gene            complement(18712..19914)
                     /gene="dacC"
                     /locus_tag="RH288_002500"
     CDS             complement(18712..19914)
                     /gene="dacC"
                     /locus_tag="RH288_002500"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HDV4031546.1"
                     /translation="MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
                     KLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQP
                     NRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY
                     TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRVWDFVMMKFH
                     QWFGSWFS"
     gene            20161..20787
                     /gene="gstB"
                     /locus_tag="RH288_002501"
     CDS             20161..20787
                     /gene="gstB"
                     /locus_tag="RH288_002501"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308945.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase GstB"
                     /protein_id="HDV4031547.1"
                     /translation="MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDADF
                     LAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYGQKRLWIDSPARRAEAEKWMDWA
                     NQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
                     VGDIAIVPFIYNLFNVGLTWTPRPNLQRWYQQLTERPAVRKVVMIPVS"
     gene            complement(20784..21899)
                     /gene="yliI"
                     /locus_tag="RH288_002502"
     CDS             complement(20784..21899)
                     /gene="yliI"
                     /locus_tag="RH288_002502"
                     /EC_number="1.1.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose sugar dehydrogenase YliI"
                     /protein_id="HDV4031548.1"
                     /translation="MHRPFFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWSLAFLP
                     DNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWL
                     SYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
                     FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQG
                     MAMNPWSNALWLNEHGPRGGDEINIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAG
                     TEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRI
                     LTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN"
     gene            complement(22010..22393)
                     /gene="bssR"
                     /locus_tag="RH288_002503"
     CDS             complement(22010..22393)
                     /gene="bssR"
                     /locus_tag="RH288_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HDV4031549.1"
                     /translation="MFVDRQRIDLLNRLIDARIDLAAYVQLRKAKGYMSVSESNHLRD
                     NFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNAD
                     KLENCLMSLTLSIQSLQKHAMLEKA"
     gene            22606..23931
                     /gene="rimO"
                     /locus_tag="RH288_002504"
     CDS             22606..23931
                     /gene="rimO"
                     /locus_tag="RH288_002504"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDV4031550.1"
                     /translation="MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTS
                     MVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV"
     gene            complement(23978..25306)
                     /locus_tag="RH288_002505"
     CDS             complement(23978..25306)
                     /locus_tag="RH288_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDV4031551.1"
                     /translation="MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYSLKQSVID
                     TAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRTAYADSVSPSYLYDVGPYLISSD
                     ECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
                     RFSLLSKSLAMDSENLMFSLFKNGKPVTGDEYNAKNAIFTVSEAMEHFAYLPTGLYVF
                     AYKKDVYLRVCTLIIFFAALVAVISGASCLYLVRRVINRGIVEKEAIINNHFERVLDG
                     GLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKGGYLCLFDVDKFKNI
                     NDTFGHLLGDEVLMKVVKILKSQIPVDKGKVYRFGGDEFAVIYTGGTLEELLSILKEI
                     VHFQVGSINLSTSIGVAHSNECPTVERLKMLADERLYKSKKNGRAQISWQ"
     gene            complement(25314..>26900)
                     /locus_tag="RH288_002506"
     CDS             complement(25314..>26900)
                     /locus_tag="RH288_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDV4031552.1"
                     /translation="YIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVL
                     LVVYLMTTRVFRRQFSEMTELVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEM
                     KDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGVD
                     ERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGY
                     RNLRIHKSAICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWI
                     ARNIRHAMEIGELFLVYQPIVDINTRAILGAEALCRWVSAERGIISPLKFITIAEDIG
                     FINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHECFTTIMKENG
                     LKANSLCVEITETVIERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDS
                     IKVDSQFTGDIFGTAGKIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGY
                     LYQKPMPFSAWDKSGKLVKE"
BASE COUNT         6831 a         6977 c         6476 g         6616 t
ORIGIN      
        1 ggcattgtta tcccatgccg cagacacggc caaaaatcat aagattgaca gacgggagtt
       61 ccatcatgaa aaagttagtt cttgccgctt tacttgcttc ctttactttc ggtgcttctg
      121 ccgcagagaa aatcaatttt ggcgtttcag ccacctatcc accctttgaa tctataggtg
      181 ctaataatga gattgtcggc tttgatatcg atctggcaaa agccttgtgc aaacaaatgc
      241 aggcagaatg tacttttact aatcacgcgt tcgacagcct gatcccgtcc ctgaaattca
      301 gaaaatatga cgccgtaatc tccggtatgg atatcacccc ggagcgtagc aaacaggtat
      361 cgtttaccac gccctactat gaaaactcag ccgtcgtgat tgccaaaaaa gatacctaca
      421 aaacgtttgc cgatctgaaa ggcaaacgta ttgggatgga aaacggtact acgcaccaga
      481 aatatattca ggatcagcac ccggaagtga aaactgtctc ttatgacagt tatcagaatg
      541 cctttatcga tctgaaaaat ggtcgtattg atggggtatt tggtgacaca gcggtggtaa
      601 acgaatggct gaaaaccaat ccacaacttg gtgttgctac tgagaaagtg accgatccgc
      661 aatattttgg caccggcctg ggcatcgctg tacgtccgga taacaaagcc ctgctggaaa
      721 aactgaataa cgcgctggca gcaattaaag ctgacggtac ttatcaaaaa atcagtgacc
      781 agtggttccc acagtaagat tcagaaagcc gcaaccgcgg cttgagactg atgacaaagg
      841 taaaattgcc tgatgcgcta cgcttatcag gcctacatgg cccatgcaat gtattgaatt
      901 tgcacgcttt tgtaggccgg ataaggcgtt tacgccgcat ccggcataaa caacgcgcac
      961 tttgtcagca atctgaagcc gcacatgcgg cttttttatt gcttcaccag cagcgtcagc
     1021 acttcatagt gcgcggtatg cgggaacata tcgaaaagct gcacccgttc aatacgaaac
     1081 ccaggcagtt cgcggatatc tttcgccata gtttgggcgt tacagctgga gtagatgata
     1141 aaacgcggtg ccatcgttga gagataatca cacagcggtt taccaatgcc gcggcgcggc
     1201 gggttaacca gcaccagctc cggcacatcc ccctgagcgg tggcaaactg agtggagtcc
     1261 agcgcctgaa attgcaaacg cgttaagccc agttcagcgg ctgactgctt tgcacaggca
     1321 atggcctctg atgcaatttc gatcccggtt aactgcatgt caggcgtcgc gcagtgtaaa
     1381 ccaaagcccc ccacaccgca gaacagatcc cacatatgtt taaccggcag ctgtcgtacc
     1441 cagtcgcgcg cggtggcgta caactggctg gcgaccgccg gattagtctg gaagaaactt
     1501 tgcggacgga tccacagcgg tacgtcatta aaacgctccg ccagtgcctg ttgttcggtc
     1561 aggtagatct ccgtctcccc ttccataatc gccatatgta ccggctgaat attgacggta
     1621 ataactttca gctgcggtag ttgttcgtgt aaccacggca gcgccttacg cagttgcgcc
     1681 agcttggtat cagaacgcag tacaaagcgc agcatcatgc cgccatcact ctggctttca
     1741 gtcagcagaa tgtatttcag ttcgccacgc ttacgcgcca cgttataagg cgttagcccc
     1801 gctcgggcga taaacggttt tagcgccgca aaaacgggcg caaatgaggc aggataaagc
     1861 gggcagtcac aaaggtcttc cggtgtgccg tcgcgatgca gcataccgag cagtggtttt
     1921 tcaacgctac cactcaccac cattttggct ttattacgaa acccttgttc cgggcctgac
     1981 accggcgcgc accattccac gaccggaaaa tcggcgagca gatttttaag atcggcggtt
     2041 ttagcggaga gttgctctgg aatcggctgc gttatccact gacaggaacg acagcgaccc
     2101 gcgtcgtaaa gtgcgcactg catacattga ccttcacatc atcagggccg acgattatac
     2161 acattattgc aactggaaga accgccgact ggtcgaggga acgaacagca gcatcaggat
     2221 gagcatatcc ggcagcttct gcagcatcag gctatggaag atttcacgtt ttgattcacc
     2281 gggaatgctg aacagctccg gataaccata ccccagcgaa gccgcccaca agtaacttgc
     2341 ggcggtgatt tgtgtcagca gatatagcca gcgcgcccag cgacgccctt tcaccagtga
     2401 aaacgcacac cagatctcga taaaaaccag caccagactg cttaaaaaga ccagcgttaa
     2461 gctccaggtt tgtacgctgc gatgaatgaa ctcgccaata ccgcgcacgc ccagcgtatt
     2521 gaaaatcatc agcacgtcga ggccacggat cataataatg gcgagcgccg ctacctgcac
     2581 cagcgcaggc acattcaggc gagcatgaga tgaagatgtt ttcttaaaaa atcccaacgt
     2641 ttcgtcttcc atgaaaacaa tgccgcggca tgcgcggcat tatgtagcca ggttggcaaa
     2701 ttttagtgtc ttcagccacg tcttgcacgc tggatatcgc gtatccgctg tttttctgcg
     2761 cgagccatca gataccaggc gataaatccg acaattccga ccgcaccgag aattaacgtt
     2821 gcaagggcgt tgatttccgg attcaccccc atccgcacgc tggaaaagac cagcatcggt
     2881 aacgtggtgg ctcccggccc agaaacaaag ctggcgatca ccagatcatc aagcgacaaa
     2941 gtaaaagcca gtaaccagcc agaaatgatc gcgggcatga tcatcggtag cgtaatgacg
     3001 aaaaatactt tcagcggcgt cgcaccgaga tccatcgctg cttcttctat cgagctatcc
     3061 agttcccgca gacgcgacga aataacgact gccacataag ccgtacagaa cgtgacatgc
     3121 gccagccaga tggtaagcat cccgcggtcc gcaggccagc caatggcatg agcaagcgcg
     3181 acgaataaca acaacagcga caagcccgtg atgacatctg gcatcaccag cggcgcggtg
     3241 atcataaagg caaagccatt tgatccgcga aacctgccaa agcgcaccag caccaccgcc
     3301 gcaatagtcc cgaggatcgc cgccgccgtt gccgcacagg cagcaattgt caggcttaaa
     3361 ccaaccgcac tcatcatcgc gtcatcgcgc aataactcac cataccagcg cgttgaccag
     3421 ccggcccaca ccgtcaccag tttcgagctg ttgaatgaat agatcaccag catcagcatt
     3481 ggcgcgtaga gaaaggtgaa gcccaacagc aaaatcacaa tccgccaggg cgaacgaact
     3541 accggtaaat tattcatccg tgttctccca cgcttttttg ctggtgtttg tgaaaccaca
     3601 ttatcggcac aattagcagc agcaacatga tgatcgctac cgccgaggcc accggccagt
     3661 cgcggttgtt aaagaactcc tgccacagca cgcgcccgat catgatgctg tccgggccac
     3721 cgagcagttc cgggatcaca aactcgccca cagccgggat aaacaccagc atcgatccgg
     3781 caataatccc acctttagtc agcggcacga tcacattaaa gaacgttttc agcggtcgtg
     3841 caccgagatc cagcgctgct tccaccagcg aataatcaat acgaatcaac gcggtataaa
     3901 tcggcagtac cataaacggc acgtaagcgt aaacaatgcc gatataaacg gccagattgg
     3961 tatgcagaat ggtcagcggt tgatcgataa cccccagcca cagcagaaaa ttattcagca
     4021 caccgttgtt ttttaatatt cccatccagg cgtagacacg aatcagaaac gaggtccacg
     4081 acggcaggat caccagtagt aataagatat tacgggtcga aggcttactg tgcgccactg
     4141 cccacgccag cggatagccg atcagtaaac agcaaaatgt cgaaatcgca gccacctgta
     4201 gcgactggag ataagcatcg aaatagagcg gatcgtcggt cagttgcagg aaattaccga
     4261 gattaagagt gatggacagt tgcccgtcag cccactccat cagttcggta taaggcggaa
     4321 tggcgcgcgc catctccgcc agacttattt taaagacgat cagaaatggc agcagaaaca
     4381 gcaagatcaa ccagatatat ggcaacgcaa tgaccagttt gcgcccatgc ttcatttgca
     4441 gctgcgacaa ccacagctta aatccgcccg gcggtttcga ctgggcagca ggttcaagtg
     4501 tattcatctt tgctccttaa accgtcagca ccacacagct gtccacttcc cagcacaaac
     4561 gcacttcgtc gccccaggtc ggtaaccctt tacgatgacg atgggcgttt tgtagctggg
     4621 cgctaatcat ctgcccactt ttcagacgaa cgtgatacac cgaaagatcg ccgagatagg
     4681 caatatgtat cacctccccc accgcgaagt tacaaccatt ggcgggcggc tcttcgcaaa
     4741 gcatgatttt ttccgggcgc agagccacat gtaccggcac gttatcgacc accgaggcat
     4801 ccgcgtcgac tttcagtgga tgcaccagcc ccggcgaatc aagcaccagg ccatcttcct
     4861 gacgctcttt gagtacgcct tcaaagacgt ttaccgagcc aataaattcg gcgctatagc
     4921 gggtagtcgg atgctcgtag atctcttccg gttcgccaat ctggacaaat ttcccacgat
     4981 tcataatggc gatgcgcccc gccatggtca tcgcctcttc ctgatcgtga gtaaccatca
     5041 cgcaggtcac accgacgcgc tccagaatat ccaccacttc aagctgcatc cggtcacgca
     5101 attttttatc cagcgcgccc atcggttcgt cgagcagcag aagttttggg cgcttggcaa
     5161 ggcttcgggc cagcgccaca cgctgtctct gaccgccgga aagctgatgc ggtttgcgtt
     5221 tggcgaactc ctgcatatgc accagcccaa gcatctcgtt gacccggctg gcaatttccg
     5281 ctttcggtag tttgtcctgt ttcaggccaa aggcgatgtt ctgctccaca gtcatatggg
     5341 gaaacaatgc gtaagactga aacatcatat tgatggggcg tagataaggt ggcacctgtg
     5401 acaaatcgac gccatcaagc ataatctgtc cggcagaggg ttgttcaaaa cctgccagca
     5461 tacgcagcag cgtggattta ccacagccgg aagcgcccag cagcgcgaag atttcacctt
     5521 tgtagatagt caggctgaca tcatccaccg catgttgacc atcgtaggat ttggtgaggt
     5581 tgcggatttc taatagcggc gtcagcgcct tacgggtttt cgcctgcggg cgagggatag
     5641 cgtcattcac ggctgctctc cggcattgaa tgtgtgcaag cgcaccatga tggtgcgaat
     5701 tgccggcggg tgtggtgcgc ccgcccggca tctaaggctg cggattattt tccgctcttc
     5761 actttggtcc acgcgcgggt gcgcacacgg tcgattttcg ggtcctgcac tttcagagtg
     5821 aacagattcg cacgaacatc cgcaggcgga taaatacccg ggttctcacg gacttccgca
     5881 ctcaccagcg gcgtggctgc tttattggcg ttggcataga acacatggtc ggaaatatgc
     5941 gctactacat ccgggcgcag caggtaattc aggaactgat aggcttcgtc tttgtttttg
     6001 gcatccgcag gcatggcgaa tacatcaaag aacgccatcg ccccttcttt tggaatcgag
     6061 aacgagacat tcactccatt cttcgcttcc ttcgcgcggt ttgacgcctg ccagacatca
     6121 cctgcccagc cgatagcgac gcaaatatcg ccgtttgcca ggtcgttaat gtattgagat
     6181 gaatggaaat aacgaatgtt cgggcgcagc tttaacagca gatctgttgc cggtccggtg
     6241 taatcatccg ctttagtgct gttaggatct ttgccgagat aattcaacac ggtagcaaaa
     6301 acttcttctg gcgcatccag gaaagagaca ccgcagcttt tcagtttttc cagattttca
     6361 ggtttgagga tcaagtccca gctatcgacg ggcgcgtttt cgcccagcac cgctttaact
     6421 ttatcaacgt tatagccaat cccggtcgtc gcccacatat agggcatagc aaatttattg
     6481 tcgggatcgt gtttggcgac cagcttcagc agttccgggt cgagattctt ccactccggc
     6541 aatttgcttt tgtccagcgg ctggaaaact cccgcagtca actggcgctc cagaaagctg
     6601 gcagatggaa ccaccagatc aaagccggta ctcccggcca ttaatttgcc ttccagtact
     6661 tcgttagagt cgaaaacatc gtagacgact ttaataccgg tttctttttc aaaattggcc
     6721 accgtgtccg gggcgatata atcagaccag ttataaatgt ggagtgtttt ttgttcagcc
     6781 gcgagcgtgc cgacagagac ggccatcaga gcacccgcaa ccagacccga tagccatttt
     6841 ttatttaagg cggtcatatc tctttccttc tgaaagttcg ttaacaaacg aacaaaagtt
     6901 gtcacactga aagatatgca ataaacgtgc atatttttta tcggcgcggt gtaagaaaag
     6961 agaactttct cccggccagc actgctcgct atataaaagc atcgcaagaa taactttagc
     7021 cagggtttga gactatagct cggattaaaa aacggtattt aacaaatttt tatgcatatt
     7081 tgctctatgt gataaagcca aatcgacaca agagaagtga aataatcttt aagaaaaggt
     7141 taaaaacagc agataatttt gcagcgcgca gccactgcac cagcgactgc gtgctcgaaa
     7201 ggagttatca gtggaggaaa tagttttcgg taacgttgtt ttgcccttca tcatcagtcg
     7261 gtaacagcag ttgatgggca ttagcttcaa gaatgaccat cgaaatctgc tcttcgctct
     7321 gacgcacgaa ccatgcaaac tgctcatagg ttacgccctg cataacggat aaagactggc
     7381 aaaccaccag ctttggcaga ttatcatcct gcatatcaag aaatgctttc acggtcagcg
     7441 aactggcatt gatggcagat aaatccgccg ccagcggcaa tacggctgaa ggtcggactt
     7501 ccgccatggc agaaaacagg atcgtgttat cgatcagatc gattttggca tcaaagacac
     7561 cgtcgaaatt ctgcatatgg ggcagatgca gagcctgaca gttatcacat tcaaaaaaac
     7621 tcatccccag gtcatcgagc cattgacgca gcgtatccag accaggaacg accagcgatg
     7681 tcataatttt gtacaacctc tttcgataaa aagaccggca cagcttacgc aaaaagcgca
     7741 ggcaaaacca tgatcagtaa tgtgattgcg actaaccacc cgttttcagg caatattctg
     7801 tcgtagcgtg gcgttcgatc cagcggatca ttttacccgc gatgtcgata ccggtggttt
     7861 tttctattcc ttccagcccc ggcgacgcat tcacctccat caccaacggc ccgcgattag
     7921 cacgcagaat atccacacca gcaacgtcca gcgccatcgt tcgcgcggct tttatcgcga
     7981 tttcacgctc ctgtggtgtg atactggcga cgcttgccgc gccgccacga tgcaaattgg
     8041 aacgaaaatc gccctctttc gcccgccgtt caatcgcagc gaccacttca tcgccaacaa
     8101 ccagacagcg gatatcgcac ccttgcgcct ctttgatata ttcctgcacc agaatatgcg
     8161 cgttcagacc gcggaaagcg tcaatcacgc tttccgccgc ctgacgcgtc tccgccagca
     8221 cgacgccaat tccctgcgtg ccttcaacca acttgaccac cagcggcgca ccaccgacca
     8281 tgtcgattaa atcgctggta tcatccggcg aatgcgcaat gcccgtgaca ggcaggtcga
     8341 tgccctgacg cgccagcagt tgcatggaac gcaatttgtc acgcgcccgg gcaatggcga
     8401 ccgactcatt gagcggatag ctccccagca tctcgaactg gcgcagtgcc gccgtcccat
     8461 aaaaggtaat ggcggtgcca atacgcggga tcactgcgtc aaaatggggt aacttgcggc
     8521 ctttgtagtg aatagaagac gccgcaggat ttatgttcat gtagcaagaa agcggatcaa
     8581 gaatttcaac caggtgaccg cgctgtatag cggcttcacg cagccgctta cacgaataga
     8641 gcgttccatc ccgggacaat atggcaattt tcaccctgca cctctctgtc agacctggtc
     8701 aaaagcccgc gtatcataca tcgacgtggc ggttttagcg cgtcgcccaa ccctgtttgt
     8761 gcaaataatc cagaataaat gggcggcttt ctttaatgat tgttcggcgg atatgatcgc
     8821 tccaggtatc ccggcgatta ttgctgccac gggtgaggta atattccgcc agttgctcgt
     8881 catactgcgc cagtgcgcct ttatccagcg gttgatagct gttttcatgc accaaaatgg
     8941 aggccggtaa acgcggctta agatccggat tatccgcagg ccagccaagg cacagcccaa
     9001 acagcggcag aacatgctgc ggtaatttaa gcagtttcgt caccgcttca atattattgc
     9061 gcaggccgcc gatatatacc ccgcccaatc ccagcgattc cgctgcgatt aatgcattct
     9121 gcgccatcat tgccgtatca acgacaccga gcaacagttg ttccgccagg ccgagctgag
     9181 catccggaca gatctgtaaa tggcggttaa agtcggcaca gaacacccag aactccgccg
     9241 cttgcgctac gtgtttttgc ccgccggtca gcgtcaccag ttcttcacgt aacgctttgt
     9301 cggtaatgcg aataatgcta ctgcactgca aaaaactgga actggacgtc gcacgggcgc
     9361 tgttaataat cgcctcacgc tgcgcttcgg aaatgggttc atcagtgaaa tggcgaatgg
     9421 agcgatggcc acaaataagt tcaatggttg gcgtcattat ctttttctct ttctgaacgt
     9481 gaatattgcg gtggacggtt catcagctgt ggggcaagac gttttgccac ctgaagaata
     9541 accaccaccg cagcgggaag catgagcaaa acaccgagaa aaatcatcag aatctgcact
     9601 tctggccgag aaaatggctc aggcagcgac agggagtcgc ttaccgacag cagcgccacc
     9661 gccagtagca tcattccgat aaattccagt atcaacacgc ctttaggcaa tttaccgatc
     9721 gcgcgcatac gcttccctct gcaaagtgag ccttcagtct aaaacttttc actgtattgt
     9781 gtttaacagt tatagctttt agcaattaat gcaacaggtt aaacctactt tcagcgaata
     9841 cattttagcg tgatcattac aggcataaat ctatgaggag agaaataatg caaaccgtta
     9901 tttttggtcg ttcgggttgc ccttactgtg tgcgtgcaaa agatctggct gagaaattga
     9961 gcaatgaacg cgatgatttt cagtatcagt atgtagatat tcgtgcggaa gggatcacta
    10021 aagaagatct acaacaaaag gcaggtaaac ccgtagaaac cgtgccgcag atttttgtcg
    10081 atcagcaaca tatcggcggc tataccgatt ttgctgcatg ggtgaaagaa aatctggacg
    10141 cctgatcgtc tgacaagccc tcgcgttgag ggctttactg attttttctg tgctgtggtt
    10201 taaacaaact actgataaat aagaaacaca gtgcccccag cgcacaccag aacaccgcgc
    10261 ttagtaacca tgccagctct tgccagaatg agcgcgtcgg tgaaaaaaac agccgcataa
    10321 tgagcatcga acagggtgcc gccagcattg cgccaaacag aggtttcagg acttctctac
    10381 gctgtgaaaa gaagctggcg actgctccag gaagaatgaa aaatagcaag ccgatttcag
    10441 gatgcccggc agcccgaaaa gcgcctttca tgtgcgtcgc cagaaaaagg cacaccacaa
    10501 tgaagaggac aaaacagcag attgcccccg cccaacgttg tttatgtttc actcgttcct
    10561 cctgacactg cgtctatcga acacattttt cgccagtgtg gcgttcagta agataaagcc
    10621 gcttcgcatt ccatgctaat ataggccaac gcaattcata tagccgttga tacctaatgt
    10681 gattacacta gtaaaatata ttgttacttt actatcgttt aggtgcgctg aatgaatctg
    10741 cgccctgaat tctggtaaaa aacattatcg taaattacca tttctttcaa cagcttacta
    10801 gtaaacaaga agttagcctc cgtgaatata aacgtcgccg aattgttaaa tgggaattac
    10861 attctgttat tatttgtggt cctcgcgctt gggctatgtc tcggaaagtt acgacttggt
    10921 tcgatccaac tgggtaattc cattggcgtt ttagtcgtat cgctgttatt aggccaacaa
    10981 catttcagca ttaacaccga tgcgcttaat cttggcttta tgctgtttat tttctgcgtc
    11041 ggggtcgaag ccggaccgaa ctttttttcc attttttttc gcgatgggaa aaattaccta
    11101 atgttagcac tggtgatggt tggcagtgcg ctggtgatcg ccttagggtt aggtaagctg
    11161 tttggctggg atattggcct gacggccggt atgttagcag gctctatgac gtcgacaccg
    11221 gttctggtcg gtgctggcga tacactgcgt cattccggca tggaaagcag gcagctctca
    11281 ctggcactgg ataatctgag cctcgggtat gccttaacct atttaatcgg tctggtgagt
    11341 ttgattgttg gtgcgcgtta cttgccgaaa ttgcagcatc aggacttaca gaccagcgcc
    11401 cagcaaatcg cccgcgaacg tggcctggac actgatgcca accgtaaggt ttatttaccg
    11461 gtgatccgcg cctatcgcgt cggcccggaa ctggtggcct ggaccgacgg caaaaatctg
    11521 cgtgaactgg gtatttatcg acaaaccggc tgctacattg aacgtattcg acgtaacggg
    11581 attctggcaa atccagacgg tgatgccgtg ctacaaatgg gcgatgaaat agcgttggta
    11641 ggctatcccg acgcccatgc ccgactcgat cccagcttcc gtaacggtaa agaagttttc
    11701 gatcgtgacc ttctcgacat gcgtatcgtc actgaagaag tggtcgttaa aaaccataac
    11761 gctgtaggta aacgtctcgc acaactgaag ttgaccgatc acggttgctt ccttaaccgc
    11821 gtcattcgta gccagattga gatgccgata gatgacaacg tcgtgcttaa caaaggtgac
    11881 gttttacaag tcagcggcga tgcccgccgc gtaaaaacca tcgccgatcg catcggcttt
    11941 atctcgattc acagccaggt cactgacctg ctggcattct gcgccttctt tgttattggg
    12001 ctgatgatcg ggatgatcac cttccagttc agcacattca gtttcggcat ggggaacgct
    12061 gccgggttgt tattcgccgg aattatgctg ggctttatgc gtgctaacca cccgaccttc
    12121 ggttacattc cgcagggtgc attaagcatg gtgaaagagt tcggcttgat ggtgtttatg
    12181 gcaggcgttg gtctgagcgc cggtagcggt attaataacg gcctgggcgc gattggcggt
    12241 cagatgttga ttgccggatt gattgtcagt ctggtgcccg tggttatctg tttcttgttc
    12301 ggtgcttatg tattgcgaat gaaccgcgcg ctgttgttcg gcgcaatgat gggcgcacgt
    12361 acctgcgcgc cggcaatgga gatcatcagt gatacagctc gcagtaacat cccggcgctg
    12421 ggctatgcgg gcacctatgc aatcgccaac gtcctgctga cgctggcagg gacaatcatc
    12481 gtcatggtat ggccaggatt aggataaaac tgaagttgcc ctgaaaatga aatttttttg
    12541 cacaaccgca gaacttttcc gcagggcatc agtcttaatt agtgccactg cttttctttg
    12601 atgtccccat tttgtggagc ccatcaaccc cgccatttcg gttcaaggtt gatgggtttt
    12661 ttgttatcta aaacttatct actaccctgc aaccctctca accatcctca aaatctcctc
    12721 gcgcgatagc ggcttacggt cggtgacaaa atgcagcgtc atcccctcaa taaacgcatc
    12781 aagcgcgcgg gcggttccgg gttcaaacca ttgttcgagc gtttgctgac tgcgctgcat
    12841 ccagttttgc attaccgttt ttaatagcgg ttttcggcta gccagcgcgt agagctggta
    12901 catcagctcc atgttatccg gcgttgcaac ctgtgagctg tagatcatat cggtgatagc
    12961 ctggcatgcg cccggagcat cactaacatc gctaaaaaat gcctgatatt gccgggacat
    13021 gatctcagta aaactgctga acgcctccag taacaactca tcaattcctg aaaaatagta
    13081 ggtcatcgat cccaacggta ccccggcaag ggtagcaatt ttgcggtgcg taacagcatg
    13141 tattccgtaa agtttcaccg cctccagcgt ggcctggata attttttctc gccgttgcgg
    13201 atcgttagcg cgacgcatgt catttcctct ctctgcaatt gtgtacaaat gtacacaacc
    13261 ttgctaatgt tgtcttccct cttcttattt tgacgtgatc tatgaccgta aattcttcac
    13321 gtaatgcatt gaaacgccga acctgggcgc tgtttatgtt cttctttttg ccaggcctgt
    13381 taatggcgtc ctgggcaacc cgtacgcctg ctatccgcga tattctctct gtctcgatcg
    13441 ctgaaatggg cggtgttctc tttggtctgt cgatcggttc gatgagcggt attctctgct
    13501 cggcgtggtt agtgaaacgc tttgggacac gtaatgtcat cctggtcacg atgtcctgcg
    13561 cattgatcgg gatgatgata ttaagtctgg cactctggct gacatcgccc ctgctctttg
    13621 ccgttggtct cggcgtcttt ggggcaagtt ttggttctgc ggaagtggcg ataaacgttg
    13681 aaggtgctgc cgttgagcga gaaatgaata agacggtttt gccgatgatg cacggttttt
    13741 atagcctggg cacgctggca ggcgcaggtg tcgggatggc actgacggcc tttggcgttc
    13801 cggcaacggt gcacatttta ttggcggcgc tggtaggtat cgcacctatt tatatcgcca
    13861 ttcaggcaat ccctgacggt acgggcaaaa atgctgccga tggcacccag catggcgaaa
    13921 aaggcgtacc tttttatcgc gatatccagt tgctgctgat aggtgttgtg gtgctggcga
    13981 tggcctttgc cgaaggttct gccaacgact ggttaccctt attaatggtt gacggtcacg
    14041 gttttagccc tacttccggc tcgctgattt atgccggttt taccctgggg atgaccgttg
    14101 gacgcttcac cggcggttgg ttcatcgacc gttacagtcg cgttgccgtg gttcgggcca
    14161 gtgcactaat gggggcgttg ggtattgggc tgattatttt tgtcgatagc gcctgggtcg
    14221 ctggggtgtc tgttgtactc tggggactgg gtgcctcgct gggcttcccg ctgaccattt
    14281 ctgccgccag cgataccggc cccgatgcac caacccgcgt cagtgtggta gcaacgaccg
    14341 gttatctggc tttcctcgtc gggccgccgc tgctgggcta tctcggcgaa cattatggat
    14401 tacgtagtgc aatgctggtt gtactggcgc tggttattct cgcggctatt gtcgcgaaag
    14461 ccgtcgccaa acccgatacc aaaacgcaga cggcgatgga gaatagttga tgagcattaa
    14521 attaattgcg gtagacatgg atggtacttt cttaagcgat caaaaaacct ataaccgtga
    14581 gcggtttatg gctcagtatc agcaaatgaa agcacaagga attcgctttg tagtcgccag
    14641 cgggaatcaa tattatcagt tgatctcttt cttccctgaa attgctaatg aaattgcctt
    14701 tgtggctgaa aacggcggct gggtagtgag cgaaggcaaa gatgttttta atggcgagct
    14761 atcgaaggat gcgtttgcta ctgtcgtgga acatttgctg acgcgcccgg aagtggaaat
    14821 tattgcctgc ggaaaaaata gtgcctatac actcaaaaaa tatgacgatg ccatgaaaac
    14881 ggtggcggaa atgtattatc accgtctgga atacgtcgat aactttgaca acttagagga
    14941 tatcttcttt aagtttggcc tgaatctttc cgatgaactg attccacaag tacaaaaagc
    15001 attacatgag gccatcggcg atattatggt gtcggtccac accggcaacg gcagcatcga
    15061 tctgattatc cccggcgtac ataaagccaa tggccttcgc caactgcaga aattatgggg
    15121 aatagacgac agcgaagtgg tggtctttgg cgatggcggt aacgatattg agatgctgcg
    15181 tcaggcaggc tttagttttg caatggaaaa tgccggcaac gcggtcgtcg cagcggcaaa
    15241 ataccgggca ggctccaata accgtgaagg cgtactggat gtgatcgata aagttcttaa
    15301 acacgaagcg ccatttgacc aataaaaacg gcagcacgcc cggcaacaca atacctgaat
    15361 gaaggctgca taattcgcgg aaattaaccc gctgcattat ttcaggcgaa atgtttatga
    15421 aaaattgtct actgttgggc gcgcttttaa tgggctttac tggtgtggcg atggcgcaaa
    15481 gtgtcaccgt cgatgtgccg agtggataca aagtggttgt ggttcctgat tcagtcagcg
    15541 ttccacaagc ggtcagcgtc gcgactgtgc cgcaaaccgt ctatgtggct cctgcgccag
    15601 ctccggctta ccgcccgcat ccttatgttc gccatcttgc cagcgtaggt gaagggatgg
    15661 ttatcgaaca ccagattgac gaccatcacc attaattcga gaatgcctga tcgcacaaag
    15721 caatcaggca tttttttacc cttcgtgaga atttcccatc tgtttatctt ttaaaaagat
    15781 aaccatcagc gacagccaca aaattccgtt tacaaggttg aagagattaa acagtccgtt
    15841 gcccccgttc agccaggcat gtttgctgat ttcaataccg acggtaaaaa tcagcatttg
    15901 cagcattccc atcgccgcag aaaccgtacc tttactcata tcgctggcaa acagggttaa
    15961 tcgcaccagt cccgcattcg ccagaccaat accgaaagca taaatactta acccggcagt
    16021 catccataaa tacgcgtgcg atgagataac cgttgccgca gcagcgacca acagaccaat
    16081 cataatcggc cagccgccca taattatcag cgaacgtacg gtgcggcgcg aggtcagacg
    16141 cgctaacagc aagttacccg caattaacgc cccgaaaata ggcacctgca gcaagccata
    16201 ttcatagctg ctcaactgct cgccagtaat gatgataatc ggcgactggg cgatccacgc
    16261 cagcaatggc aggctaacga atcccagcgc cagcgccccc gccacaaagc ggccgttctt
    16321 cagcaccagc ttatagtcac gaccgagttc tttcagtgac agtttctcgc ctatacgcgt
    16381 ggcggtttca ggcatggctc gttgcagacc gaaaaaggag atcgctgcca atgcggcaaa
    16441 caagacgaac atcccttccc agggcagcac atggatccac gccgcgccca ccagcggacc
    16501 aagtagcgga gcaatcagcg ccacgttcgc catcagcgcg gtgatcttga tacaaaccgc
    16561 ctcttcgaag gattcctgaa ttgcggcgta tcccacagcg ccaatgaaac agaggcttat
    16621 gccctgcaag aagcgcaaca gggtgaattg ttcaatgttt tgcgccagca atattgccag
    16681 acaggtgacg ataaaccaca ccactcccgc cagcatcacc ggacggcgac caatacgatc
    16741 cgacagcggc cccagcagcc attgtaaaaa catcccgccc gccagatacg cggtcatcga
    16801 agtaggaacc caatcaatgc ccgcctgata ttgttccacc acggccaaca taccgggttg
    16861 aatcatatcg ttgccgatat aggttgaaaa ttcgtaaagc accagacaga gagggaaaag
    16921 taacgcctga cgtccaagcc tggcaccgga agctaattta ttttgcatgc aatttcttcg
    16981 ccaataataa tcgcgcagag tttaataaaa gcgcagctaa cgagaaagcg aattttgtag
    17041 ctgaaaccac ggttaagcac attcttacat tattgcgagt atagctacgc tttctttaag
    17101 ttttatttaa cctatgcccg ttacaatcac ccaccgtaaa caggccgctt gagggaaata
    17161 agacgatgcc gctttaccca gtttaacctg cactttattc tcaacgactt gcctgtattg
    17221 gctccctttt aatcactttg cgtcgggaag ttatgctgga aaatttgaat ctctctctat
    17281 tctctcttat taacgcgacg ccagactcgg ctccgtggat gatctcgttg gcgattttta
    17341 ttgctaaaga tttgattacc gtggtgccgt tgctggccgt ggtactttgg ttgtgggggc
    17401 ttacagcaca acggcaactg gtgataaaaa tcgctatcgc gctggcggtc agcctgtttg
    17461 tgtcctggac gatgggacat ctttttccgc acgaccgacc ctttgtcgaa aatatcggct
    17521 ataacttcct gcatcatgcg gcggatgact cattcccaag cgatcacggt acggtgattt
    17581 tcacctttgc actggcattt ttatgctggc atcgcctgtg gtccggctca cttttaatgg
    17641 tgctggccgt cgtcattgcc tggtcgcgcg tttatcttgg cgtccactgg ccgctggata
    17701 tgctcggtgg attgctggca ggtatgattg gctgccttag tgcccagatt atctggcaag
    17761 cgatggggca taaactctat caacgtctgc aatcgtggta tcgcgtctgt tttgcattac
    17821 cgatccgcaa aggctgggtg cgtgactgat ctctgctaaa aagtgtagta ttgagcggct
    17881 cgcttcaata actattcaga gggattatgg aaacacgtcg cgaagagcgt atcgggcagc
    17941 tgctgcaaga attaaaacgc agcgataagt tacatcttaa agacgccgcc gccctgcttg
    18001 gggtttcgga gatgacgatt cgtcgcgatc tgaacaacca cagtgcgccc gtcgttttgc
    18061 tcggcggcta tattgttctg gaaccgcgca gtgccagcca ttacctgtta agcgatcaaa
    18121 aatcccgcct ggtggaagaa aaacgccggg cggcaaaact ggctgcgacg ctggtagaac
    18181 ccgatcagac cctctttttt gactgtggca ccaccacgcc gtggattatt gaagcgattg
    18241 ataatgaaat cccttttacc gccgtttgtt attcgctaaa tacctttctg gcgctgaaag
    18301 agaaacccca ttgccgcgcg tttctttgcg gtggtgaatt tcacgccagc aacgccattt
    18361 tcaaacccat cgattttcag caaacgctga ataatttttg cccggatatc gctttctatt
    18421 ctgcggcggg cgtgcatgtc agtaaaggcg ctacctgttt taatcttgaa gagttgccgg
    18481 taaaacactg ggccatgtcg atggcgcaaa agcatgtgct ggttgtcgac cacagtaaat
    18541 ttggcaaggt gcgtccggcg cgcatgggtg acctgaaacg ctttgatatt gtggtgagcg
    18601 attgttgccc ggaagatgag tatgtgaagt acgcgcagac gcagcgcatt aagttgatgt
    18661 attaatgacg tataaccgga tgacgtttcg cgccatccgg ttatcagaag attaagagaa
    18721 ccagctgccg aaccactgat ggaatttcat catcacgaaa tcccacaccc gaccaaagaa
    18781 tccgccctct tccacatttt ccatcacgat cagcggacgc tgctcaatgg atttaccgtt
    18841 aagctggaaa tcaatggtcc cgacaacctg accttttttc agcggtgcgg taagctgcgg
    18901 ttccgttaac gtataactcg ctttcaggtt tttcagctgc ccacgcggta tggtcactga
    18961 gcccgcttca cctgccccga gattcacttc gctcttatca ccaaaccaga cgcgctgagt
    19021 cacaaaggtg gcatcaggtt taattggcgt cacggtttca aagaagcgga aaccccaggt
    19081 caataatttc tcagactcat taaaacggat acggtcagtt ttcgccccca gcactacgga
    19141 gattaaacgc atatcaccct gggtagccga agcaaccaga ttatatcccg cacctgccgt
    19201 ggttcctgtc ttcatgccat caacattcag attgctgctc cacagcagac ggttacggtt
    19261 aggctgacga attttgttga aggtgaactc tttctcttta tgaatggcgt actcttccgg
    19321 cacatcgtgg atcaatgctt tacccagcaa tgccatatcg cgcgcggtac tgaactgccc
    19381 cggcgcatcc agaccgtgca ccgtctggaa ggtagtgttg gtcagaccca gttttttggc
    19441 ataaccattc atcaaaccaa taaatgactc ctggctcccg gcaacgtaat cggccagcgc
    19501 aatacaggcg tcattaccgg actggataat cacacctttg ttcaagtctg ccaccgaaac
    19561 ctgatcgccc ggtttgagga acattaccga tgaaccacgc agtgccggat ttcccgtcgc
    19621 ccaggcatct ttaccgaccg tcaccatatc ggtgagttta atcttatcgg ccttaagcgc
    19681 ctgcccaacc acatagctgg tcatgatttt agtcaggctc gcgggatcca gtttctcatc
    19741 cgcgttgcct tctgccagca ctttaccgct ggcgtaatcc attaaaatcc atgcacgcgc
    19801 atccacgctc ggcgcttcaa cggtttgttc cgccgcgaat gccgttgggg caaaaaggaa
    19861 taaaaatgca gaacccgctg caagaccacg aaggagagag gagtattgcg tcataaatgc
    19921 cacccgagta tccattcaaa aaaaatacgt tatatcgccg tatgataagt ttggtgatta
    19981 ataacgcaca cacaaactta aagaaaccgt aagttggtaa agtttttaaa gtttatgcaa
    20041 tatcctgccg cttcgctgct tctggtgtca tttttttgcc agctgttgct taaaagttaa
    20101 ctttacttca ccatcggagt cctgttcagc ctgtggctgc ctgtcggaaa aggggtgagt
    20161 atgattacgc tgtggggtcg gaataattca actaacgtaa aaaaagtatt gctgacgctc
    20221 gaagaactgg aactacctta tgagcaaatt ctcgcgggcc gtgagtttgg gataaatcac
    20281 gatgctgatt ttctggcgat gaaccctaac gggctggtgc cgttgttgcg tgacgacgaa
    20341 agtgatctca ttctttggga atcaaacgcc attgtccgct atctggcggc acagtacggg
    20401 caaaaacgcc tgtggatcga ctcaccggca cgtcgtgcgg aagcggaaaa atggatggac
    20461 tgggcaaacc agacgctcag taatgctcat cgcgggatcc tgatgggatt agtcagaaca
    20521 ccaccggaag agcgcgatca ggccgccatt gatgccagtt gcaaagagtg cgacgccctg
    20581 tttgccctgc tcgatgcgga actggcaaaa gtaaaatggt tctctggcga cgagtttggt
    20641 gtgggcgata tcgctatcgt accgttcatc tacaatttgt ttaacgttgg cctgacctgg
    20701 acaccgcgtc caaatctgca acgctggtat cagcaactca ctgaacgccc cgcagtgcgc
    20761 aaagtggtga tgattcccgt tagctaattg cgtgggctaa ctttaagtaa ttccccactg
    20821 gactcgtcgg tgagaacgta taaataaccg tcgggtccag tgcgaacatc acgaattcgc
    20881 tgccctctgt ccgttaaaat acggccatct tctgtcactt tgtcgccgtt gacgctcatc
    20941 acaatgacat ctttatcttt cagcgcgcca ataaataatt tttgctgcca ctgggggaat
    21001 ttatcgctgt tatagaaggc catgccgctc acagcgggcg aatctttcca gtaaaaaaca
    21061 ggttgctcgg tcccggcgac gatctcccct ttcgcttccg gtatcttaaa gcctgaatag
    21121 ttgattcccc aggttgccag cggccagccg tagtttttgc ctttttgcgg gatattaatt
    21181 tcatcaccac cgcgcgggcc atgttcattc agccacagtg cattactcca cggattcatc
    21241 gccattcctt gcggattacg aatgccataa gaccagatct cggcgcgcgc accggattcc
    21301 tttataaaag gattatcatc cgggatttcg ccctggtcgg tcagacgcac cagtttgccc
    21361 tgtaatttat ccagatcctg cgccgtcggg cgctgattgt tttcgcccag agcaataaaa
    21421 agataacctt taccgtcgaa taccagccgc ccgccaaaat ggttgccggt agacagtttt
    21481 ggcatctggc gaaagacggt gcggaagtcg gtcacttttg agagatcatc acttaagcgg
    21541 ccataaccca cagcagttcc ggctttgcca tcatcgccaa cttcggaata acttaaccag
    21601 atgcggcgag actgagcaaa atcaggcgct aaaaccacgt ccagcaggcc gccctgcccg
    21661 tgcgcccaaa cgtccggcac tccggaaagc ggcgcagata atccttttcc tgcttgccag
    21721 tgacgcaact cgccgccgcg cagagtgatt aacataccgt gattatcggg taaaaaggcc
    21781 agtgaccagg gatggtcgag tttgtcttgc agtacttcga catttaccgt tgcaggagcc
    21841 gcccagagag cggaagaaag acaaataagg ggcacaagga aaaagaatgg tcgatgcata
    21901 acgcctccgg attgactctg gcttaaagcg tagtcagtgg aggagataac aaattcattt
    21961 ttacaaaaac ttaaacatga agggggagac gctttctccc ccttagtttt caggccttct
    22021 caagcatggc gtgcttctgc aggctctgga tactcagcgt taagctcatc agacaatttt
    22081 caagcttatc ggcgttgacg gtaataacag tcgggcaatc atggtgccca ctcatcaaac
    22141 atactgcggc tgtcgctaat gcttcttcag catgatgaag agcactccac tcttcctgat
    22201 ccagatgaag attcaaccgc agcgatttat cgtgcagttc gcgattcagt ttaaaaaagt
    22261 tatctcgtag atgattgctt tcgctgacgg acatgtatcc ttttgccttc ctcagttgca
    22321 cgtatgcggc gaggtcaatg cgtgcgtcga tcaaccggtt cagcagatcg attcgctgtc
    22381 tgtcaacgaa catacttcga tcctcctctt tccagccttg ttgcaattaa atagtatggc
    22441 tattttttga gcaaaatgct gtccaggatc aattcttcac gccgaattaa caaaatttac
    22501 atttccttcg cctccgccag cgaatgagat tgcgatacaa attttatcca gaactctgta
    22561 gaatccctgc cctgaccttt cctgtaactg aatatttttt aagctatgag caaagtaact
    22621 ccccagccga aaatcggctt tgtttccctt ggctgtccga aaaaccttgt tgattcagag
    22681 cgtattctca ccgaactccg cactgaaggt tatgacgtgg taccgagcta tgacgatgcg
    22741 gacatggtga tcgtcaacac ctgcggcttt attgacagcg cggtacaaga atcactggaa
    22801 gccattggtg aagcgttgaa tgaaaacggc aaggttattg tgaccggttg tctgggggca
    22861 aaagaagatc agatccgcga agtccacccg aaagtgctgg aaatcaccgg gcctcatagc
    22921 tatgagcagg ttctggagca cgttcatcac tacgtgccga aaccgaaaca caacccattc
    22981 ctgagcctgg tgccagaaca aggtgtgaaa ctgacgccgc gtcattatgc ctatctgaaa
    23041 atttctgaag gctgtaatca ccgctgcacc ttctgcatta ttccgtctat gcgcggcgac
    23101 ctggtgagcc gtccgattgg cgaagtgtta agtgaagcga aacgtctggt agatgcgggc
    23161 gttaaagaga ttctggtgat ctcgcaggat acttccgcct atggcgttga tgttaaacat
    23221 cgtactggct tccacaacgg cgagccggta aaaaccagca tggtcagcct gtgcgaacag
    23281 ttatcgaaac tggggatctg gacacgtctg cactacgttt acccttatcc gcatgtggac
    23341 gacgtcatcc cactgatggc agaaggcaaa atcctgccgt atctggacat tccgttgcag
    23401 cacgccagcc cgcgcattct caaactgatg aagcgtccgg gttctgtaga tcgccaactg
    23461 gcgcgcatca aacagtggcg cgaaatctgc ccggaactga ccctacgctc aacctttatt
    23521 gtcggcttcc ctggcgagac ggaagaagat ttccagatgc tactcgactt cctgaaagaa
    23581 gcgcgtctgg atcgcgttgg ctgctttaaa tacagcccgg ttgaaggtgc agacgccaat
    23641 gccctgcctg accaggttcc ggaagaagtg aaagaagaac gctggaaccg tttcatgcag
    23701 ctgcagcagc agatttccgc cgagcgcctg caagagaaag tgggccgtga aattctggtg
    23761 attatcgacg aagtggacga agaaggcgca attggtcgca gcatggcaga tgcaccggaa
    23821 atcgacggcg cggtttatct caatggtgaa accaacgtta agccgggtga tatcctgcgt
    23881 gtgaaagtcg agcacgccga tgagtacgat ttgtggggta gccgggttta attaattcag
    23941 gccgggcaaa atcatttgtc cggcctgcga ataatgatta ctgccagcta atctgtgccc
    24001 tgccgttttt cttactctta tacagccgct catccgccag cattttcaag cgttcgacgg
    24061 taggacattc atttgaatgt gctacaccga tactggtact taaattaatg cttcccacct
    24121 ggaaatgaac gatttctttt agaatcgata gcaactcttc cagcgttcca cccgtataaa
    24181 tcaccgcaaa ttcgtcaccg ccgaagcggt agactttacc tttatctacc gggatctgtg
    24241 atttaaggat tttcaccact ttcatcaaca cttcatcgcc cagcaaatga ccgaaggtgt
    24301 cgttaatgtt tttgaattta tcgacgtcaa acaggcacaa ataaccgcct ttttccggca
    24361 gcgcttttaa atcttcgtca aaggattttc tgcccattgc tttggtcagg tcgtccagga
    24421 acgccgagtt atacatactg tagagttttt tgacatcggc agccgaaaag aaaagcccgc
    24481 catccagtac gcgttcaaaa tggttattaa tgatggcttc tttctccaca ataccacgat
    24541 taatcactct gcgtaccaga tagaggcaac tggcacccga tatcactgcc accaatgcgg
    24601 caaagaaaat aatcaatgta caaacccgca aataaacatc ttttttatac gcaaatacat
    24661 acaatccggt cggcaaatag gcgaagtgct ccatcgcttc cgaaacggtg aagatggcgt
    24721 ttttagcatt atattcatca ccggtcaccg gtttaccgtt cttaaataga gagaacatca
    24781 ggttctcgct gtccatcgcc agcgattttg acagtaaaga aaaacgctcc agaccaagca
    24841 aaaatatcag actacgattg tgagttaccg gatagaggta atagacgaag gttttaccgt
    24901 caaaagagat aaaccctgta tttttgacat gtcgatactt cacaacctgc ataatatctg
    24961 cacaataatt tttctcgaac tcctttacct gaatacattc gtcactggaa atcagataag
    25021 gaccgacatc gtacaaataa gagggggaaa ccgagtcggc gtaagctgtg cgcaaaccaa
    25081 ccaacagctg ttcctccgtg ggatttagcg tgttgataag atcaattgcc acgctacgcc
    25141 gatattcagc aatatttgcc accgcaaaag cagtatcaat aacggactgt ttcaggctat
    25201 acacccgttc ctttaccatt tgagtgtaga tcccgcaggc aactgctgaa atcatgataa
    25261 aaatcagcag actgactgta agtacgaact tattgattct ggacatacgt aaactactct
    25321 tttactaatt ttccactttt atcccaggcg gagaatggca tgggtttctg gtacagatac
    25381 ccctgagcct gaacacatcc taatttaatt aattcgcgcg caacgtcttc gctctctacg
    25441 ccttccgcaa tcaccgggat ccggttatag cgtgccagat cgaaaataat gcgcacaatt
    25501 tttcccgcag taccgaaaat atcgccggta aattgcgagt ccacctttat gctgtctgga
    25561 ttaatttcat aaaaacgttt caggtttgac aaaccggtgc caaagtcatc aatcgatatc
    25621 cgtacccctt gtttacgcag ttgttcaata ttgagataaa aatgttcatt aattcgctcg
    25681 atcacggttt cagtgatctc aacacagagg ctgttcgcct tcaggccatt ttctttcatg
    25741 atggtggtaa aacactcatg aaagtgcggt tcgtttaact gccagggcga aacattaata
    25801 tgcagtaaga aatcatcctt cagcgacgca cgctgactaa aatgtctgaa ttcacccatt
    25861 gccgttttaa taatctgata acccagctca ttgataaacc cgatatcttc agcaatggta
    25921 atgaacttca gcggtgaaat gatcccccgc tccgcagaaa cccaacggca caacgcctcc
    25981 gcgcccagaa tggcgcgggt gttaatatca acgatcggtt gatagacgag gaatagttcg
    26041 ccaatttcca ttgcatggcg aatattacgc gcaatccaga tattctcttc tatttcgttg
    26101 agtttcgcgt catcacagaa aataaactcg gagaacatat ggtcacggat actggaaatc
    26161 gccagtttca gtttttctgc gtaactccag gcgttttccc cctgcaaagg ttcacaaatg
    26221 gcagacttat ggatgcgcag attgcggtag ccaaagctgc tgtcaaaatc gtttaccatc
    26281 gctattttac gggtaaatgt ctgtacattt tcccgacaca gaagtaaata gagatcggca
    26341 ttgaatgtca cgatatcgca gcattgcgca tatttctcgg caattcgctg acacaatttc
    26401 ctgacgattt tattgcgttc atcaacacca aacaccgctt ccacggcttc cagaccacac
    26461 agtttgatga tccccacagc cagatactga ttattgttgg actcaataat cgccatattt
    26521 ttaataaaac cgctttcctg atcgtaagag atcagtgaga gcaatttatt tgaccgttca
    26581 atttcggcat ctttcatttc cgcgatcgaa tttttaatgc tgataatctc tttcgcatcg
    26641 ccttcgcgaa ttttcagagc ctcgatttga tccgttgagt cgggcaaaaa tgccagcgta
    26701 ttaaccagct ctgtcatttc agaaaattgc cgacggaaca cacgagtggt cattaaataa
    26761 accaccagca atacgataat aatgaacgca aacggcagat aaaaaagttt atctgatgcg
    26821 ttcaataaat taccgccagg ataataaaaa tagatttcga ataatgcgtt gtttggcacc
    26881 gctgatgttt tttcgatata
//
LOCUS       DAPHKZ010000057        26672 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.057, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000057 DAPHKZ010000000
VERSION     DAPHKZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26672
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.057"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            441..1580
                     /gene="wza"
                     /locus_tag="RH288_002507"
     CDS             441..1580
                     /gene="wza"
                     /locus_tag="RH288_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein Wza"
                     /protein_id="HDV4031553.1"
                     /translation="MMKSKMKLMPLLVSVTLISGCTVLPGSNMSTMGKDVIKQQDADF
                     DLDKMVNVYPLTPRLIDQLRPRPNVARPNMTLESEIANYQYRVGPGDVLNVTVWDHPE
                     LTTPAGQYRSSSDTGNWVQPDGTMFYPYIGKVHVVGKTLAEIRSDITGRLATYIADPQ
                     VDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTILDAINAAGGLTDTADWRNVVLTHN
                     GREERISLQALMQNGDLNQNRLLYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSGM
                     TLTEALGNAEGIDMTTSNASGIFVIRPLKGEGGRNGKIANIYQLDMSDATSLVMATEF
                     RLQPYDVVYVTTAPVSRWNRLINQLLPTISGVRYMTDTASDIHNW"
     gene            1586..2029
                     /gene="wzb"
                     /locus_tag="RH288_002508"
     CDS             1586..2029
                     /gene="wzb"
                     /locus_tag="RH288_002508"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase Wzb"
                     /protein_id="HDV4031554.1"
                     /translation="MFNNILVVCVGNICRSPTAERLLQRYHPELKVESAGLGALVGKG
                     ADPTAISVAAEHQLSLEGHCARQISRRLCRNYDLILTMEKRHIERLCEMAPEMRGKVM
                     LFGHWDNECEIPDPYRKSRETFAAVYTLLERSARQWAQALNAEQV"
     gene            2032..4194
                     /gene="wzc"
                     /locus_tag="RH288_002509"
     CDS             2032..4194
                     /gene="wzc"
                     /locus_tag="RH288_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416564.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wzc"
                     /protein_id="HDV4031555.1"
                     /translation="MTEKVKQHAAPVTGSDEIDIGRLVGTVIEARWWVIGITAVFALC
                     AVVYTFFATPIYSADALVQIEQNSGNSLVQDIGSALANKPPASDAEIQLIRSRLVLGK
                     TVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMVDQVFTLNVLDDK
                     NYTLSSDGGFSARGQAGQMLKKEGVTLMVEAIHASPGSEFTVTKYSTLGMINQLQNSL
                     TVTENGKDAGVLSLTYTGEDREQIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQL
                     PEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLY
                     TKVHPAYRTLLEKRQALEEEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNK
                     EQELKITEASTVGDVRIVDPAITQPGVLKPKKGLIILGAIILGLMLSIVGVLLRSLFN
                     RGIESPQVLEEHGISVYASIPLSEWQKARDSVKTIKGVKRYKQSQLLAVGNPTDLAIE
                     AIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLLIDCDMR
                     KGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSER
                     FTELVNWASKNYDLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSR
                     FEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK"
     gene            4372..5211
                     /gene="wcaA"
                     /locus_tag="RH288_002510"
     CDS             4372..5211
                     /gene="wcaA"
                     /locus_tag="RH288_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaA"
                     /protein_id="HDV4031556.1"
                     /translation="MKDNPLISIYMPTWNRQQLAIRAIKSVLRQDYSNWEMIIVDDCS
                     TSWEQLQQYVTALNDSRITYIHNDINSGACAVRNQAIMLAQGEYITGIDDDDEWTPNR
                     LSVFLAHKQQLVTHAFLYANDYVCQGEVYSQPASLPLYPKSPYSRRLFYKRNIIGNQV
                     FSWAWRFKECLFDTELKAAQDYDIFLRMVVEYGEPWKVEEATQILHINHGEMQITSSP
                     KKFSGYFHFYRKHKDKFDRASKKYQLFTLYQIRNKRMTWRTLLTLLSVRNGKRLADGI
                     RGR"
     gene            5214..5702
                     /gene="wcaB"
                     /locus_tag="RH288_002511"
     CDS             5214..5702
                     /gene="wcaB"
                     /locus_tag="RH288_002511"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaB"
                     /protein_id="HDV4031557.1"
                     /translation="MLEDLRANSWSLRPCCMVLAYRVAHFCSVWRKKNVLNNLWAAPL
                     LVLYRIITECFFGYEIQAAATIGRRFTIHHGYAVVINKNVVAGDDFTIRHGVTIGNRG
                     ADNMACPHIGNGVELGANVIILGDITIGNNVTVGAGSVVLDAIPDNALVVGEKARVKV
                     IK"
     gene            5699..6916
                     /gene="wcaC"
                     /locus_tag="RH288_002512"
     CDS             5699..6916
                     /gene="wcaC"
                     /locus_tag="RH288_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaC"
                     /protein_id="HDV4031558.1"
                     /translation="MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGK
                     ESVSHQNYPQVIKHTPRMTAMANIALFRLFNRDLFGNFNELYRTITRTPGPVVLHFHV
                     LHSYWLNLKSVVRFCEKVKNHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP
                     TLNNYPPVKIDRAHQLVAGKRQLFREMLALGCQFISPSQHVADAFNSLYGPGRCRIIN
                     NGIDMATEAILADLPPVRETQGKPKIAVVAHDLRYDGKTNQQLVREMMALGDKIELHT
                     FGKFSPFTAGNVVNHGFETDKRKLMSALNQMDALVFSSRVDNYPLILCEALSIGVPVI
                     ATHSDAAREVLQKSGGKTVSEEDVLKLVQLSKPEIAQAIFGTTLAEFSQRSLAAYSGQ
                     QMLEEYVNFYQNL"
     gene            6891..8108
                     /gene="wcaD"
                     /locus_tag="RH288_002513"
     CDS             6891..8108
                     /gene="wcaD"
                     /locus_tag="RH288_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative colanic acid polymerase WcaD"
                     /protein_id="HDV4031559.1"
                     /translation="MSTSIRICSYLLLPLIYLLVNVKIAQLGESFPITIVTFLPVLLL
                     LFLERISVKKLMIALGIGAGLTAFNYLFGQSLDASKYVTSTMLFVYIVIIIGMVWSIR
                     FKTISPHNHRKILRFFYLVVGLVVALAAVEMAQIILTGGSSIMESISKYLIYSNSYVL
                     NFIKFGGKRTTALYFEPAFFALALISIWLSIKQFGIKTPKTDAMILSGIILSGSFSGV
                     MTFILFYLLEWAFQYLNKEAIKKKLPLALISLAVFLVGVVIAFPYISTRLGDLGTEGS
                     SSYYRIVGPLVMVGYSLSHIDGVVRFGSLYEYVASFGIFNGADVGKTIDNGLYLLIIY
                     FSWFAVLLSLCYMGKVIKMMINAFGDNRNFRVQLYLFTPVSLFFTGSIFSPEYAFLIV
                     CPFILRKALNITR"
     gene            8119..8865
                     /gene="wcaE"
                     /locus_tag="RH288_002514"
     CDS             8119..8865
                     /gene="wcaE"
                     /locus_tag="RH288_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaE"
                     /protein_id="HDV4031560.1"
                     /translation="MLLSIITVAFRNLEGIVKTHASLAHLAQADDISFEWIVVDGGSN
                     DGTREYLENLNGIYNLRFVSEPDNGIYDAMNKGIAMAQGKFALFLNSGDIFHQDAANF
                     VRRLKMQKDNVMITGDALLDFGDGHKIKRRAKPGWYIYHSLPASHQAIFFPVSGLKKW
                     RYDLEYKVSSDYALAAKMYKAGYAFKKLNGLVSEFSMGGVSTTNNMELCADAKKVQRQ
                     ILHVPGFWAELSWHLRQRTTGKTKALYNKV"
     gene            8881..9429
                     /gene="wcaF"
                     /locus_tag="RH288_002515"
     CDS             8881..9429
                     /gene="wcaF"
                     /locus_tag="RH288_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaF"
                     /protein_id="HDV4031561.1"
                     /translation="MQDLSGFSVPKGFRGGNAIKVQLWWAVQATLFAWSPQVLYRWRA
                     FLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDDVNLYTLGEITIGAHSVISQ
                     KSYLCTGSHDHASRHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKS
                     LPANRVCRGNPAVVIRERVETE"
     gene            9456..10577
                     /gene="gmd"
                     /locus_tag="RH288_002516"
     CDS             9456..10577
                     /gene="gmd"
                     /locus_tag="RH288_002516"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HDV4031562.1"
                     /translation="MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRF
                     EGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWK
                     PEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES"
     gene            10580..11545
                     /gene="fcl"
                     /locus_tag="RH288_002517"
                     /gene_synonym="wcaG"
                     /gene_synonym="yefB"
     CDS             10580..11545
                     /gene="fcl"
                     /locus_tag="RH288_002517"
                     /gene_synonym="wcaG"
                     /gene_synonym="yefB"
                     /EC_number="1.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HDV4031563.1"
                     /translation="MSKQRIFIAGHRGMVGSAIKRQLEQRGDVELVLRTRDELNLLDS
                     RAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKL
                     LFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMA
                     AASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASK
                     PDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG"
     gene            11548..12027
                     /gene="gmm"
                     /locus_tag="RH288_002518"
                     /gene_synonym="nudD"
                     /gene_synonym="wcaH"
                     /gene_synonym="yefC"
     CDS             11548..12027
                     /gene="gmm"
                     /locus_tag="RH288_002518"
                     /gene_synonym="nudD"
                     /gene_synonym="wcaH"
                     /gene_synonym="yefC"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="HDV4031564.1"
                     /translation="MFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGY
                     WFVPGGRVQKDETLEAAFERLTMAELGLRLPMTTGQFYGVWQHFYDDNFSGTDFTTHY
                     VVLGFRFSVAEEELLLPDEQHDDYRWLTPDALLASDNVHPNSRAYFLAEKRAGVPGL"
     gene            12024..13247
                     /gene="wcaI"
                     /locus_tag="RH288_002519"
     CDS             12024..13247
                     /gene="wcaI"
                     /locus_tag="RH288_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis fucosyltransferase
                     WcaI"
                     /protein_id="HDV4031565.1"
                     /translation="MKILVYGINYSPELTGIGKYTGEMVEWLAAQGHEVRVITAPPYY
                     PQWQVGENYSAWRYKREEGAATVWRCPLYVPKQPSTLKRLLHLGSFAVSSFFPLMAQR
                     RWKPDRIIGVVPTLFCTPGMRLLAKLSGARTVLHIQDYEVDAMLGLGLAGKGKGGKVA
                     QLATAFERSGLHNVDNVSTISRSMMNKAIEKGVAAENVIFFPNWSEIARFQHVADADV
                     AALRNQLGLPDNKKIILYSGNIGEKQGLENVIEAADRLRDEPLIFAIVGQGGGKARLE
                     KMAQQRGLRNMQFFPLQSYDALPALLKMGDCHLVVQKRGAADAVLPSKLTNILAVGGN
                     AVITAEAHTELGQLCETFPGIAVCVEPESVEALVAGIRQALLLPKHNTVAREYAERTL
                     DKENVLRQFIHDIRG"
     gene            13250..14686
                     /gene="cpsB"
                     /locus_tag="RH288_002520"
     CDS             13250..14686
                     /gene="cpsB"
                     /locus_tag="RH288_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanyltransferase"
                     /protein_id="HDV4031566.1"
                     /translation="MSQSKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTT
                     ICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAA
                     KRHSPDSDPLMLVLAADHVIADEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGY
                     IRRGEVSAGEQDTVAFEVAQFVEKPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELK
                     KYRPDILDACKKAMSAVDPDLDFIRVDEEAFLACPEESVDYAVMERTADAVVVPMDAG
                     WSDVGSWSSLWEISAHTAEGNVCHGDVINHKTENSYVYAESGLVTTVGVKDLVVVQTK
                     DAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITV
                     KPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGAKHCLENPGKI
                     PLDLIEVRSGSYLEEDDVVRFADRYGRV"
     gene            14788..16158
                     /gene="cpsG"
                     /locus_tag="RH288_002521"
                     /gene_synonym="manB"
     CDS             14788..16158
                     /gene="cpsG"
                     /locus_tag="RH288_002521"
                     /gene_synonym="manB"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis phosphomannomutase
                     CpsG"
                     /protein_id="HDV4031567.1"
                     /translation="MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLG
                     GDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLF
                     GYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIP
                     NPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAHPVEAINR
                     VEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEARTRTL
                     LTLLNE"
     gene            16213..17607
                     /gene="wcaJ"
                     /locus_tag="RH288_002522"
     CDS             16213..17607
                     /gene="wcaJ"
                     /locus_tag="RH288_002522"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HDV4031568.1"
                     /translation="MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSF
                     LYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATEFALLLQNWTLSVIFSAGLVAFN
                     NDFDTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLM
                     ESFRNQPWLGFEVVGVYHDPKPGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGA
                     RVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVVPLYDTPLSGVNRLLKRA
                     EDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMKVME
                     NDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYR
                     QLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIV
                     FLTVFKGFVNKAAY"
     gene            17609..19087
                     /gene="wzxC"
                     /locus_tag="RH288_002523"
     CDS             17609..19087
                     /gene="wzxC"
                     /locus_tag="RH288_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid undecaprenyl disphosphate flippase
                     WzxC"
                     /protein_id="HDV4031569.1"
                     /translation="MSLREKTISGAKWSAIATVIIIGLGLVQMTVLARIIDNHQFGLL
                     TVSLVIIALADTLSDFGIANSIIQRKEISHLELTTLYWLNVGLGIVVCVAVFLLSDLI
                     GDVLNNPDLAPLIKTLSLAFVVIPHGQQFRALMQKELEFNKIGMIETSAVLAGFTFTV
                     VSAHFWPLAMTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVAPNLRFGAWLTA
                     DSIINYLNTNLSTLVLARILGAGVAGGYNLAYNVAVVPPMKLNPIITRVLFPAFAKIQ
                     DDTEKLRVNFYKLLSVVGIINFPALLGLMVVSNNFVPLVFGEKWNSIIPVLQLLCVVG
                     LLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAIVIGGQMAGAIGVTLGFLLVQI
                     INTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTLVVSYALGLLLKGQLALGMLLA
                     VQIAAGVLAFVVMIVLSRHPLVVEVKRQFCRSEKMKMLLRAG"
     gene            19159..20439
                     /gene="wcaK"
                     /locus_tag="RH288_002524"
     CDS             19159..20439
                     /gene="wcaK"
                     /locus_tag="RH288_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis pyruvyl transferase
                     WcaK"
                     /protein_id="HDV4031570.1"
                     /translation="MKLLILGNHTCGNRGDSAILRGLLDAINILNPHAEVDVMSRYPV
                     SSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNI
                     AIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGP
                     FQDEQFNQLANYVFGHCDALILRESVSLDLMKRSNITTAKVEHGVDTAWLVDHHTEDF
                     TASYAVQHWLDVAAQQKTVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQV
                     IALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGT
                     RLHSAIISMNFATPAIAINYEHKSAGIMQQLGLPEMAIDIRHLLDGSLQAMVADTLGQ
                     LPALNARLSEAVSRERQMGMRMVQSVLERIGEAK"
     gene            20436..21656
                     /gene="wcaL"
                     /locus_tag="RH288_002525"
     CDS             20436..21656
                     /gene="wcaL"
                     /locus_tag="RH288_002525"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaL"
                     /protein_id="HDV4031571.1"
                     /translation="MKVGFFLLKFPLSSETFVLNQITAFIDMGFEVEIVALQKGDTEN
                     THAAWTKYNLAARTRWLQDEPTGKVAKLRHRASQTLRGIHRKNTWQALNLKRYGAESR
                     NLILSAICCQVATPFHADVFIAHFGPAGVTAAKLRELGVIRGKIATIFHGIDISSREV
                     LNHYTPEYQQLFRRGDLMLPISDLWAGRLQKMGCPREKIAVSRMGVDMTRFSPRPVKA
                     PATPLEIISVARLTEKKGLHVAIEACRQLKEQGVAFRYRILGIGPWERRLRTLIEQYQ
                     LEDVVEMPGFKPSHEVKAILDDADVFLLPSVTGADGDMEGIPVALMEAMAVGIPVVST
                     LHSGIPELVEADKSGWLVPENDARALAQRLAAFSQLDTDELAPVVKRAREKVEHDFNQ
                     QVINRELVSLLQAL"
     gene            21667..23061
                     /gene="wcaM"
                     /locus_tag="RH288_002526"
     CDS             21667..23061
                     /gene="wcaM"
                     /locus_tag="RH288_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein WcaM"
                     /protein_id="HDV4031572.1"
                     /translation="MPFKKLSRRTFLTASSALAFLHTPFARALPARQSVNINDYNPHD
                     WIASFKQAFSEGQTVVVPAGFVCDNINTGIFIPAGKTLHILGSLRGNGRGRFVLQDGS
                     QVTGEEGGSMNNITLDVRGSDCTIKGLAMSGFGPVTQIYIGGKNKRVMRNLTIDNLTV
                     SHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILISDHIIERINCT
                     NGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIK
                     ARNITPDFSKKAGIDNATVAIYGCDNFAIDNIEMINSAGMLIGYGVIKGKYLSIPQNF
                     RVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLFMRNIKV
                     MQESSVGPALSMSFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRINHHIV
                     NVEKINFRLPERRE"
     gene            23236..24129
                     /gene="galF"
                     /locus_tag="RH288_002527"
     CDS             23236..24129
                     /gene="galF"
                     /locus_tag="RH288_002527"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalF"
                     /protein_id="HDV4031573.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     gene            24551..25831
                     /gene="tviB"
                     /locus_tag="RH288_002528"
     CDS             24551..25831
                     /gene="tviB"
                     /locus_tag="RH288_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001507568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     UDP-N-acetylglucosamine C-6 dehydrogenase TviB"
                     /protein_id="HDV4031574.1"
                     /translation="MSFNLENYKIGIIGLGYVGLPLAVEFGKKIKTLGFDINEKRIKE
                     LSAGNDFTLECSSDELAQAYYLQYSCDYKELATCNVFIVTVPTPIDEYKQPDLTPLVK
                     ASETLGKIIKKDDIIIYESTVYPGATEEVCIPVIEKISGLVFNIDFFAGYSPERINPG
                     DKEHRVTTIKKVTSGSTPEIAEIVDKLYGTIITAGTHKASSIRVAEAAKVIENTQRDL
                     NIALINELAMIFNKLGIDTEEVLKAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQA
                     IGYHPEVILAGRRINDGMSKYIASQFIKAMLKKKFQIEGANVLIMGLTFKENCPDLRN
                     TKVVDILAELKEYNVNVDIYDPWVDVEEAYYEYGVNVLNTLSDKKYDGVIFAVAHSQF
                     KNMSKEEVHGIIRNDGVIYDLKYIIDPNLVDIRL"
     gene            25868..>26672
                     /locus_tag="RH288_002529"
     CDS             25868..>26672
                     /locus_tag="RH288_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDV4031575.1"
                     /translation="MKYKKIEDALSSKSETWLITGVAGFIGSNLLEALLKLNQKVVGL
                     DNFATGHQANLDEVKESVSAEQWSAFTFVEGDICEPETCVEVVKGVDHVLHQAALGSV
                     PRSIKDPITTNNTNISGFINMLVAAKDANVRSFTYAASSSTYGDHPALPKIEENIGNP
                     LSPYAVTKYVNELYAQVFARTYGFKSIGLRYFNVFGKRQDPNGAYAAVIPKWTAAMIN
                     DEPLYINGDGETSRDFCFIENVVQMNILAAQSDASARDQVYNVAVGDRTT"
BASE COUNT         6747 a         6469 c         7101 g         6355 t
ORIGIN      
        1 taaaaaccat attgaatgac acttaatata attcttaaaa atagccaatt gccgaattgt
       61 taccttgcct gctattccgt tagctgtaac acttcctcct gcattattgg agagctaata
      121 ttcaattacc ataatgtcac cttatattcg gaagttaatt tccgcaataa ccctttctca
      181 tcaacgattg tatgcagaga gggtttgaaa aattaagcta aatcagtgta ttggtggcta
      241 aaaagccagg ggcggtagcg tgtctggatg cctgaaagac cagtctgaat tattctgtca
      301 atagcctgcg gatgaaatca atttttttag gactgatgcc agttaaattt ttattcaatt
      361 aactgcaagg taaatgtgca tggcgacatt gctattaata gtgcacagga taattactct
      421 gccaaagtga taaataaaca atgatgaaat ccaaaatgaa attgatgcca ttattggtgt
      481 cagtaacctt gataagcggt tgcacagtac ttccgggcag caatatgtcg acgatgggta
      541 aagacgtcat caaacagcag gatgctgatt tcgatctcga caaaatggtg aatgtttatc
      601 cgctgacccc gcgcctgatt gatcaattac gcccacgccc aaacgtcgcg cgccccaata
      661 tgacgctgga aagcgagatt gccaattatc aatatcgtgt cgggccgggc gacgttctta
      721 atgtcaccgt ctgggatcac ccggaactca ccacgccagc tggtcagtac cgcagctcca
      781 gcgacaccgg caactgggta cagcctgacg gcaccatgtt ctacccgtat atcggcaagg
      841 ttcacgtagt ggggaaaacg ctcgctgaaa tccgcagtga tattaccggg cgcttagcga
      901 cgtacatcgc tgacccacag gtggacgtta atatcgctgc cttccgctcg caaaaggcct
      961 atatctccgg tcaggtgaat aaatccggtc aacaggcgat caccaacgtg cctctgacca
     1021 ttctcgacgc cattaacgcc gcaggtggcc tgaccgatac cgctgactgg cgcaacgtgg
     1081 tgctaacaca caatggtcgt gaagaacgca tttctttgca ggcgctgatg caaaacggcg
     1141 acctcaatca gaaccgactg ctttatcctg gcgatattct ctacgtgccg cgtaatgatg
     1201 atctgaaagt atttgtgatg ggtgaagtga aaaaacagag caccctgaaa atggacttta
     1261 gcggcatgac cttgactgaa gccctgggca atgccgaagg tatcgacatg accacctcca
     1321 acgccagcgg catctttgtc attcgtccgc tgaaaggcga gggcgggcgt aacggcaaga
     1381 tcgccaatat ctaccaactg gatatgtccg atgccacgtc gctggtgatg gcgacagaat
     1441 tccgcctgca gccttatgac gtggtgtatg tcaccaccgc tccggtttcc cgctggaacc
     1501 gtctgatcaa tcagttgctg ccaactatta gcggtgtccg ttacatgacg gatacagcca
     1561 gcgacattca taactggtaa tcgtcatgtt taacaacatc ttagttgtct gtgtcggcaa
     1621 tatttgccgt tccccgacgg cggaacgctt actgcaacgt tatcaccctg agctgaaagt
     1681 agaatccgct ggactcggcg cgctggtcgg taagggcgct gatcctaccg ctatcagcgt
     1741 cgccgcagaa catcaactgt ctctggaagg tcactgtgca cggcaaatca gccgccgcct
     1801 gtgtcgcaac tacgacctga tattgactat ggaaaagcgc catatcgaac gcttatgcga
     1861 gatggcacct gagatgcgcg gcaaagtgat gctgtttggt cactgggata acgaatgtga
     1921 aatccccgat ccgtatcgca aaagccggga aacgtttgca gcggtgtaca cattacttga
     1981 acggtctgcc cgccagtggg cgcaggcatt gaacgcagag caggtataac aatgacagaa
     2041 aaagtaaaac aacatgccgc tccggtaacg ggcagtgatg aaatcgatat tggtcgcctg
     2101 gtcggcaccg tcattgaagc gcgctggtgg gtaattggca tcaccgccgt attcgccctc
     2161 tgtgccgtgg tttacacctt cttcgccacg ccgatataca gcgccgacgc actggtacaa
     2221 atcgagcaaa acagcggcaa ttcgttagtg caggatatcg gctcggcgtt agctaacaag
     2281 ccgccagcat cggacgctga gatccagttg attcgctcgc gtctggtgct cggtaaaacg
     2341 gtggacgatc tcgacctcga tattgcggtg agcaaaaaca cgttcccgat tttcggtgcg
     2401 ggctgggatc gcctgatggg acgtcagaac gagaccgtaa aagtgaccac ctttaaccgt
     2461 ccaaaagaga tggtggatca ggtgtttacg cttaatgtgc tggacgataa aaactacact
     2521 ttgagcagcg acggcggctt tagcgctcgt gggcaagcgg gtcagatgct gaaaaaagaa
     2581 ggcgtcacgc tgatggttga agccattcac gccagcccgg gcagtgagtt taccgtcact
     2641 aaatactcaa cgctggggat gatcaatcaa ctgcaaaaca gcctgacggt aacagagaat
     2701 ggcaaagacg ctggcgtact gagcctgact tataccggtg aagatcgcga acagatccgc
     2761 gacattctta acagtatcgc ccgtaactat caggaacaaa atattgagcg caaatcggcg
     2821 gaagcgtcga aaagcctcgc cttcctcgcg caacagttac cagaagtacg cagccgcctt
     2881 gatgttgccg aaaacaaact gaatgccttc cgtcaggata aagattctgt tgatctgccg
     2941 ctggaagcga aagcggtgct tgattcaatg gtgaacatcg acgcgcagtt gaacgaactg
     3001 acctttaaag aggcggaaat ctccaagctg tacaccaaag ttcacccggc gtaccgcacg
     3061 ctgctggaga aacgtcaggc gctggaagaa gagaaggcca aacttaacgg tcgcgtaacg
     3121 gcgatgccga aaacccagca ggagattgtg cgtctgacgc gcgatgtcga gtctgggcag
     3181 caggtctata tgcaactgct gaataaagag caggagctga aaattaccga ggccagcacc
     3241 gtcggcgatg tgcgtattgt tgacccggca atcacccagc ctggcgtgct gaaaccgaag
     3301 aaagggctga ttattctcgg cgcaatcatc ctcggcctga tgctttctat cgtgggtgtg
     3361 ctgctgcgct cgttgttcaa tcgcggcatt gaaagcccgc aggtgctgga agaacacggt
     3421 atcagcgtct atgccagcat cccgctgtcg gaatggcaaa aagcgcgcga tagcgtcaaa
     3481 accatcaaag gggttaaacg ctataaacag agccagctac tggcggtggg gaatccaacc
     3541 gatctggcga ttgaagccat ccgtagtctg cgtaccagtt tgcacttcgc gatgatgcag
     3601 gcacagaaca atgtgttgat gatgaccggg gttagcccgt caatcggtaa aacctttgtc
     3661 tgcgccaacc tggcggcggt cattagccag accaataaac gggtgttgtt gatcgactgc
     3721 gatatgcgca aaggctacac ccacgagctg ctcggcacca ataacgtcaa tggcctgtcg
     3781 gaaattctga ttggtcaggg cgatattact accgctgcta aaccgacctc tattgccaaa
     3841 tttgacctga tcccgcgcgg ccaggtgccg ccaaatcctt ctgaactgtt gatgagcgaa
     3901 cgctttaccg aactggtgaa ctgggcgagt aaaaactacg acctggtgtt gattgatacg
     3961 ccgccgattc tggcagtgac cgatgccgcg attgtcgggc ggcatgtcgg aaccacgttg
     4021 atggtggcgc gttatgcggt caacacattg aaagaagtgg aaaccagtct gagccgcttt
     4081 gagcaaaacg gaattccggt gaaaggggtg attctgaact ccatcttccg ccgcgccagc
     4141 gcgtatcagg attatggcta ttacgaatac gaatataagt cggatgcgaa ataacgagat
     4201 ccgctgtcgg atgcgatgct gacgcatctt atccgaccta cgttcacgcc gcatcaggca
     4261 agcaaacccg ctccgtaggt cggataaggc gttcacgccg catccggcaa cagaacctgt
     4321 aaaccagctt ataaaccggc agaacatctc gatactccgg gagaacaacc tatgaaagac
     4381 aatccgctga tctcaatcta tatgccgacc tggaaccgcc aacaactggc gattcgggcg
     4441 ataaaatcgg tcctgcgcca ggactacagc aactgggaga tgattatcgt ggatgattgc
     4501 tccacctcct gggaacagct gcaacaatac gtcaccgccc tcaacgactc gcgcattacc
     4561 tacattcaca acgacattaa cagcggggcg tgcgcggtac gtaaccaggc gattatgctg
     4621 gcacaagggg aatacatcac cgggatcgat gacgatgatg aatggacacc caaccgcctg
     4681 agcgtcttcc tcgcccataa acagcaactg gtcacacatg cgttcttgta cgccaacgac
     4741 tacgtttgcc agggcgaagt ctattcccaa ccggcaagct tgccgctgta tcccaaatcg
     4801 ccgtattcac gccgactgtt ctacaaacgc aatatcattg gtaatcaggt gtttagctgg
     4861 gcgtggcgtt tcaaagagtg cttgttcgat accgaactga aagcggcaca ggattacgac
     4921 atcttcctgc gaatggtggt ggagtacggc gaaccgtgga aagtggaaga ggcgacgcag
     4981 atcctgcata tcaatcacgg cgaaatgcag atcacctcgt caccgaaaaa attctccgga
     5041 tacttccact tttatcgtaa gcacaaagac aaattcgacc gcgccagcaa aaaatatcag
     5101 ttgtttaccc tctaccagat ccgcaataaa cgcatgacct ggcgcacctt gttgacgctg
     5161 ctgtcggtgc gtaacggcaa acgtctggct gatggaattc gggggcgcta aagatgctgg
     5221 aagatctgcg cgccaacagc tggagtttac gcccgtgctg catggttctt gcctatcgcg
     5281 ttgctcattt ttgttcagtg tggcgcaaaa aaaacgtcct caacaatctg tgggcggccc
     5341 cgctgctggt gttgtatcgc attatcaccg aatgcttttt cggttatgaa atccaggccg
     5401 ccgcgaccat tggccgacgc tttactatcc atcacggcta tgccgtagtg atcaataaaa
     5461 acgtggtcgc gggggatgat ttcaccattc gccacggcgt cactatcggc aatcgtggtg
     5521 ccgataacat ggcatgtcca cacattggca acggcgtcga gcttggtgcc aacgtcatta
     5581 ttctcggcga tatcacgatt ggtaacaacg ttaccgtggg ggcgggcagc gtggtgctcg
     5641 acgcaatccc ggacaacgcg ctggtggtgg gagaaaaagc gcgagtgaag gtaattaaat
     5701 gaatattctg caatttaatg tgcgactggc ggaaggcggg gcggcaggtg tggcgttaga
     5761 tctccaccag cgcgcgctgc aacaggggct ggcgtcacat tttgtctacg gctacggcaa
     5821 aggcggcaaa gagagcgtca gccatcagaa ctatccgcag gtcatcaaac atacgccgcg
     5881 gatgaccgcg atggcgaaca ttgccctgtt tcgtctgttt aatcgcgatc tgttcggcaa
     5941 tttcaatgag ttatatcgca ccattactcg cacaccggga ccggtagtcc tgcattttca
     6001 tgtgctgcac agctactggt tgaatcttaa gagcgtggtg cgcttttgcg aaaaggtgaa
     6061 aaaccacaaa ccggatgtca ctttggtctg gacactgcac gatcactgga gcgttaccgg
     6121 acgctgtgct tttaccgacg gttgcgaagg ctggaaaacg ggctgccaga aatgcccgac
     6181 cttaaataac tatccgccgg tgaagattga tcgcgcacac cagctggtgg cgggcaaacg
     6241 ccagttattc cgcgagatgc tggcgctggg ctgtcagttt atttccccca gccagcatgt
     6301 ggctgatgct ttcaatagcc tgtacggtcc agggcgttgc cggattatca ataacggtat
     6361 tgatatggca accgaagcga ttctggcgga cctgcctccg gtgcgcgaaa cccagggtaa
     6421 gccgaaaatc gcggtggtgg cgcatgacct gcgttacgac ggcaaaacta accagcaact
     6481 ggtgcgcgag atgatggcgc tgggtgacaa aatagaactg catacctttg gtaagttttc
     6541 gccgttcacc gctggtaacg tggttaatca cggctttgaa actgacaagc gcaagttgat
     6601 gagcgcgctt aatcagatgg atgcgctggt gttcagttct cgcgtcgata actacccgct
     6661 gattttgtgt gaggcgttat caattggtgt gccggtgatt gccacccata gcgatgcggc
     6721 gcgggaagtg ctgcaaaaat ccggcggtaa aaccgtcagc gaagaagacg tgctgaaact
     6781 ggtgcagtta agcaaaccgg aaatcgcgca ggcgatattt ggtaccacgc tggctgagtt
     6841 cagccaacgc agcctcgccg cctacagtgg acaacagatg ctggaggagt atgtcaactt
     6901 ctatcagaat ctgtagctac ctgctgctgc cgctgattta cctgctggtt aacgtcaaaa
     6961 tcgcccagct tggcgaaagt ttccccatca ccatcgtcac ttttttacct gtcttgttac
     7021 tgctgttttt agagcgcatc agcgttaaaa aattgatgat tgccttaggg attggtgcgg
     7081 gactcacggc gtttaactac ctgtttggtc agtcgctgga tgccagtaaa tacgtcactt
     7141 caactatgct gtttgtctat attgtgatca ttattggcat ggtgtggagt attcgcttta
     7201 aaacgatttc gccacacaac catcgcaaga tattacgttt cttttatctg gttgtggggc
     7261 tggtggtggc gctggcggcg gtggagatgg cgcaaattat cctcactggc ggcagcagta
     7321 ttatggagtc gatttcgaaa tatctgattt acagcaacag ttatgtgctg aatttcatta
     7381 aattcggcgg caagcgtacg acagcacttt atttcgaacc ggcatttttc gctctggcat
     7441 taatctcaat ttggctcagc atcaaacagt ttggtatcaa aacgcctaaa accgatgcta
     7501 tgattctctc agggataata ttatccggat cgttttcagg ggttatgacc tttatcctgt
     7561 tttatttgtt ggagtgggcg tttcaatatc tgaacaaaga ggcgattaag aaaaagttac
     7621 cgttagcatt gatttctctg gctgtattcc tggttggtgt ggtaatcgcg tttccttata
     7681 tttccacccg cttgggcgat ttaggtacgg aaggatcgtc atcgtattat cgcattgtcg
     7741 gtccactggt gatggtcggt tattctttga gccatattga cggtgtagtc agatttggct
     7801 cactttatga atatgtcgca tcattcggaa tatttaacgg tgcggatgtc ggaaaaacca
     7861 tagacaatgg tttgtatctg ctgattattt atttttcctg gttcgcagtg cttttatcac
     7921 tgtgttacat ggggaaagtg ataaaaatga tgatcaacgc ttttggtgat aatcgcaatt
     7981 ttcgtgtgca gctctatctt tttactccgg tgtcgctgtt ttttaccggt tcgatattta
     8041 gcccggagta tgcattttta atcgtctgtc catttatttt gcgaaaagcg ttaaatatta
     8101 cgaggtaaga ataagaacat gttgcttagc ataatcactg tcgcgtttcg taacctcgaa
     8161 gggatagtca aaacacacgc ctcgctggcg catctggcgc aggctgacga tatcagcttc
     8221 gaatggattg ttgtcgatgg cggttccaat gacggcaccc gtgagtatct ggaaaatctc
     8281 aatggtatct ataacctacg ctttgtcagc gagccagata acggtatcta cgacgccatg
     8341 aacaaaggca ttgcgatggc acaaggcaag tttgcgttgt ttctcaactc gggcgatatt
     8401 tttcatcagg atgccgcaaa ttttgtccgt aggttaaaaa tgcaaaaaga taacgtgatg
     8461 atcaccggcg atgcactgct ggattttggc gacgggcata aaattaaacg tcgcgctaaa
     8521 cctggctggt atatttatca cagcctgccc gccagccatc aggcgatatt ttttccggta
     8581 tccggtttga aaaaatggcg ttatgacctg gaatataaag tttcttccga ttatgcgctg
     8641 gcggccaaaa tgtataaagc cggttatgca tttaaaaaac tcaatggcct ggtgtctgaa
     8701 ttttctatgg gtggggtatc taccaccaat aatatggaat tgtgtgctga cgccaaaaaa
     8761 gtccaacgac aaatattaca tgtgcctggc ttctgggctg aattatcctg gcatttacgc
     8821 cagcgcacga cgggtaagac caaagcctta tataacaaag tctgaatata aggaatacca
     8881 atgcaagatt taagcggttt ctcggtgccg aaagggttcc ggggcggcaa cgctattaaa
     8941 gtgcaattgt ggtgggcagt acaggcaaca ttatttgcct ggtcgccaca agtattgtat
     9001 cgctggcggg catttttatt acgtttattc ggcgcaaaaa taggaaaaaa cgtagttatt
     9061 cgtccgtcag taaaaattac ctatccgtgg aaattaacct taggtgatta cgcgtgggtc
     9121 ggcgatgacg tcaatttata taccctcggt gaaataacta ttggcgcaca ttcggtgata
     9181 tcgcaaaaaa gttatttatg caccgggagc cacgaccatg caagtcgaca tttcaccata
     9241 aacgccacgc ccattgtgat tggcgagaaa tgctggctgg caaccgatgt ttttgttgct
     9301 cctggcgtca cgatcggcga cggcaccgtc gtgggtgcgc gaagcagtgt ttttaaatcg
     9361 cttccggcaa atagagtttg ccgggggaat cccgcagtgg tgatacgcga acgcgttgaa
     9421 actgaataaa ttcaaaaaat acagaggaat aagacatgtc aaaagtcgct ctcatcaccg
     9481 gtgtaaccgg acaagacggt tcttacctgg cagagtttct gctggaaaaa ggttacgagg
     9541 tgcatggtat taagcgtcgt gcatcgtcat tcaacaccga gcgcgtggat cacatttatc
     9601 aggatccgca cacctgcaac ccgaaattcc atctgcatta tggcgacctg agtgatacct
     9661 ccaacctgac acgcattttg cgtgaagtgc agccggatga agtgtacaac ctgggcgcaa
     9721 tgagccacgt tgcggtttct tttgagtcac cggaatatac cgcagacgtt gatgcgatgg
     9781 gcacactgcg tctgctggag gcgatccgct tccttggtct ggaaaagaaa acccgtttct
     9841 atcaggcttc cacttctgaa ctgtacggtc tggtgcagga aattccgcag aaagaaacca
     9901 cgccgttcta tccgcgatct ccatatgcgg tcgccaagct gtatgcctac tggatcaccg
     9961 ttaactaccg cgaatcctac ggcatgtacg cctgtaacgg cattctcttc aaccatgaat
    10021 ccccgcgccg cggcgaaacc ttcgtgaccc gcaaaattac ccgcgcaatc gccaatatcg
    10081 ctcaagggct ggagtcgtgc ctgtacctcg gcaatatgga ttccctgcgt gactggggcc
    10141 acgccaaaga ctacgtaaaa atgcagtgga tgatgctgca acaggaacag ccagaagatt
    10201 tcgttattgc caccggcgtt cagtactccg tgcgtcagtt cgtggaaatg gcggcagcac
    10261 agctgggcat caaactgcgc tttgaaggca cgggcgttga agagaagggc attgtggttt
    10321 ccgtcaccgg gcatgacgcg ccgggcgtta aaccgggcga tgtgattatc gccgttgacc
    10381 cgcgttactt ccgtcctgct gaagtagaaa cgctgctcgg cgacccgacc aaagcgcacg
    10441 aaaaactggg ctggaaaccg gaaatcaccc tcagagagat ggtatctgaa atggtggcta
    10501 atgacctcga agcggcgaaa aaacactctc tgctgaaatc tcacggctac gacgtggcga
    10561 tcgcgctgga gtcataagca tgagtaaaca acgtattttt atcgctggcc atcgcgggat
    10621 ggtcggttct gccatcaagc gacagctcga acagcgcggt gatgtggaac tggtattacg
    10681 cacccgcgac gaactgaacc tgctggacag ccgcgcggtg catgatttct ttgccagcga
    10741 gcgcattgac caggtctatc tggcggcggc gaaagtgggc gggattgtcg ccaacaacac
    10801 gtatccggcg gatttcatct accagaatat gatgattgag agcaacatca ttcacgctgc
    10861 gcatcagaac gacgtgaaca aactgctgtt tctcggatcg tcctgcatct acccaaaact
    10921 ggcaaaacag ccgatggcag aaagcgagct gttacagggc acgctggagc cgaccaacga
    10981 gccatacgcc attgccaaaa tcgccgggat caaactgtgc gaatcttaca accgccagta
    11041 tggacgcgat taccgctctg tcatgccgac caacctgtac gggccgcacg acaacttcca
    11101 tccaagtaat tcgcatgtga tccccgcatt gctgcgccgc ttccacgagg cgacggcaca
    11161 gaatgcaccg gacgtggtgg tgtggggcag cggtacgccg atgcgcgaat ttctgcatgt
    11221 cgatgatatg gcggcggcaa gcattcatgt catggagctg gcgcacgaag tctggctgga
    11281 aaacacccag ccgatgctgt cgcacattaa cgtcggcacg ggtgttgact gcactatccg
    11341 cgagctggcg caaaccatcg ccaaagtggt gggttacaaa ggtcgggtgg ttttcgatgc
    11401 cagcaaaccg gatggtacgc cgcgcaaact gctggatgtg acgcgcctgc atcagcttgg
    11461 ctggtatcac gaaatctcac tggaagcggg gcttgccagc acttaccagt ggttccttga
    11521 gaatcaagac cgctttcggg ggtaatgatg tttttacgtc aggaagactt tgccacggta
    11581 gtgcgctcca caccgcttgt ctctctcgac tttattgtcg agaacagtcg cggcgagttt
    11641 ctgcttggca aaagaaccaa ccgcccggcg cagggttact ggtttgtgcc gggagggcgc
    11701 gtgcagaaag acgaaacgct ggaagccgca tttgagcggc tgacgatggc ggaactgggg
    11761 ctgcgtctgc cgatgacaac gggccagttt tacggtgtct ggcagcactt ttatgacgat
    11821 aacttctccg gcacggattt caccacgcac tatgtggtgc tcggttttcg cttcagcgtc
    11881 gcggaagaag agctgttact gccggatgaa cagcatgacg attaccgctg gctgacgccg
    11941 gatgcgctgc tggccagtga caatgttcac cctaacagcc gtgcctattt tctcgctgag
    12001 aagcgtgccg gagtacccgg attatgaaaa tactggtcta cggtattaac tactcgccgg
    12061 agttaaccgg catcggcaaa tacaccggcg agatggtgga atggctggca gcacaaggtc
    12121 atgaggtgcg ggtcattacc gcaccgccgt actacccgca gtggcaggtg ggcgagaact
    12181 attccgcctg gcgctacaaa cgagaagagg gggccgccac ggtgtggcgc tgcccgctgt
    12241 atgtgccaaa acagccgagc accctgaaac gcctgttgca tctcggcagt tttgccgtca
    12301 gcagtttttt cccgttgatg gcgcaacgtc gctggaagcc ggatcgcatt atcggcgtag
    12361 tgccaacgct gttttgcacg ccgggaatgc gcctgctggc gaaactctct ggtgcgcgta
    12421 ccgtgctgca tattcaggat tacgaagtag atgcgatgct ggggctgggc cttgccggaa
    12481 aaggcaaagg cggcaaagtg gcacagctgg cgacagcctt cgaacgtagc ggactgcata
    12541 acgtcgataa cgtttccacg atttcgcgct cgatgatgaa taaagccatc gaaaaaggcg
    12601 tggcggcgga aaacgtcatc ttcttcccca actggtcaga aattgctcgt tttcagcatg
    12661 tcgcagacgc cgatgttgct gcccttcgta accaacttgg cctgccggat aacaaaaaaa
    12721 tcattcttta ctccggcaat attggtgaaa agcaggggct ggaaaacgtt attgaagctg
    12781 ccgatcgcct gcgcgatgaa ccgctgattt ttgccattgt cgggcagggc ggcggcaaag
    12841 cgcggctgga aaaaatggcg cagcagcgcg gactgcgcaa tatgcaattt ttcccgctgc
    12901 aatcttatga cgccttgcct gcactgctga agatgggcga ctgccatctg gtggtgcaaa
    12961 aacgcggcgc ggcagatgcc gtattgccgt cgaaactgac caatattctg gcggtaggcg
    13021 gtaacgcggt aattaccgca gaagctcaca cagaactggg gcagctttgc gaaaccttcc
    13081 caggaattgc ggtttgcgta gaaccggaat cggtcgaggc gctggttgct gggattcgtc
    13141 aggcgctcct gctgcccaaa cacaacacgg tggcacgtga atatgccgaa cgcacgctcg
    13201 ataaagagaa cgtgttacgt caatttatac atgatattcg gggataatta tgtcgcagtc
    13261 gaaactctat ccagttgtga tggcaggtgg ctccggtagc cgcttatggc cgctttcccg
    13321 cgtactttat cccaagcagt ttttatgcct gaaaggcgat cttaccatgc tgcaaaccac
    13381 catctgccgc ctgaacggcg tggagtgcga aagcccggtg gtgatttgca atgagcagca
    13441 ccgctttatt gtcgcggaac agctgcgtca actgaacaaa ctcaccgaga atattattct
    13501 cgaaccggca gggcgtaaca ctgcgcctgc cattgcgttg gcggcgctgg cggcaaaacg
    13561 tcatagtccg gacagcgatc cgttaatgtt ggtgctggca gcagatcatg tgattgccga
    13621 tgaagacgcg ttccgcgccg ccgtgcgtaa tgccatgccg tatgccgaag cgggcaagct
    13681 ggtcaccttc ggcattgtgc cggatctacc agaaaccggt tatggctata ttcgtcgcgg
    13741 tgaagtgtcg gcgggcgagc aggatacggt ggcctttgaa gtggcgcagt ttgtcgaaaa
    13801 accgaatctg gaaaccgccc aggcctatgt ggcaagcggc gaatattact ggaacagcgg
    13861 catgttcctg ttccgtgccg gacgttatct cgaagaactg aaaaaatatc gcccggatat
    13921 tctcgacgcc tgcaaaaaag cgatgagcgc cgtcgatccg gatcttgatt ttattcgcgt
    13981 ggatgaagaa gcgtttctcg cctgcccgga agagtcggtg gattacgcgg ttatggaacg
    14041 tacggcagat gccgttgtgg tgccgatgga tgcgggctgg agcgatgtcg gttcctggtc
    14101 ctctttatgg gagatcagcg cccacaccgc ggaaggcaac gtttgccacg gcgatgtgat
    14161 taatcacaaa accgaaaaca gctacgtgta tgccgaatct ggcctggtca ccaccgtcgg
    14221 ggtgaaagat ctggtagtgg tgcagaccaa agacgcggtg ctgattgcag accgtaacgc
    14281 ggtgcaggat gtgaaaaaag tggtcgagca gatcaaagcc gatggtcgcc atgagcatcg
    14341 ggtgcatcgc gaagtgtatc gcccgtgggg caaatatgac tctatcgacg cgggcgaccg
    14401 ctaccaggtg aaacgcatca ccgtgaaacc gggcgagggc ttgtcggtac agatgcacca
    14461 tcaccgcgcg gaacattggg tagtggtcgc gggaacggca aaagtcacca ttgacggtga
    14521 tatcaaactg cttggtgaaa acgagtccat ttatattccg ctgggggcaa aacactgcct
    14581 ggaaaacccg gggaaaattc ccctcgattt aattgaagtg cgctccggct cttatctcga
    14641 agaggatgat gtggtgcgct tcgcggatcg ctacggacgg gtgtagtagt tgaataatca
    14701 accggaataa atctccggta aataacgaca aaaacaaaat tggccgcttc ggtcagggcc
    14761 aactattgcc tgaaaaaggg taacgatatg aaaaaattaa cctgctttaa agcctatgat
    14821 attcgcggaa aattaggcga agaactgaat gaagatatcg cctggcgtat tgggcgtgcc
    14881 tatggcgaat ttctcaaacc gaaaaccatt gtgttaggcg gtgatgtccg tcttaccagc
    14941 gaaaccttaa aactggcgct ggcgaaaggg ttacaggatg cgggcgtcga cgtgctggat
    15001 atcggcatgt ccggcactga agagatctat ttcgccacgt tccatctcgg tgtggatggc
    15061 ggcatcgaag ttaccgccag ccataacccg atggattata acggcatgaa gctggtgcgc
    15121 gaaggggctc gcccgatcag cggtgatacc ggactgcgcg acgtccagcg tctggcagaa
    15181 gccaacgact tccctcccgt cgatgaaacc aaacgtggtc gctatcagca aatcaaccta
    15241 cgcgacgcat atgttgatca cctgttcggt tatatcaatg tcaaaaacct tacgccgctc
    15301 aagctggtga tcaactccgg gaacggtgcg gcgggtccgg tggtggacgc cattgaagcc
    15361 cgctttaaag ccctcggcgc accagtggaa ttgatcaaag tgcacaacac gccggacggc
    15421 aatttcccca acggaattcc taacccgctg ctgccggaat gccgcgacga cacccgcaat
    15481 gcggtcatca aacacggcgc ggatatgggt attgcctttg atggcgattt tgaccgctgt
    15541 ttcctgtttg acgaaaaagg gcagtttatc gagggctact acattgtcgg tctgctggca
    15601 gaagcgttcc tcgaaaaaaa tcccggcgcg aagatcatcc acgatccgcg tctctcctgg
    15661 aacaccgttg atgtggtgac ggccgcaggc ggcaccccgg taatgtcgaa aaccggacac
    15721 gcctttatta aagaacggat gcgcaaggaa gacgccatct acggtggcga aatgagtgcc
    15781 caccattact tccgtgattt cgcttactgc gacagcggca tgatcccgtg gctgctggtc
    15841 gccgaactgg tgtgcctgaa agggaaaacg ctgggcgaac tggtgcgcga ccggatggca
    15901 gcgtttccgg caagcggtga gatcaacagc aaactggcgc accccgttga ggcgattaac
    15961 cgcgtcgaac agcattttag ccgcgaggcg ctggcggtgg atcgcaccga tggcatcagc
    16021 atgacctttg ccgactggcg ctttaacctg cgctcctcca acaccgaacc ggtggtgcgg
    16081 ttgaatgtgg aatcgcgcgg tgatgtgccg ctgatggaag cgcgaacgcg aactctgctg
    16141 acgttgctga atgagtaatg tcggatcttc ccttacccca ttgcgggtaa ggggctaata
    16201 acaggaacaa cgatgacaaa tctaaaaaag cgcgagcgag cgaaaaccaa tgcatcgtta
    16261 atctctatgg tgcaacgctt ttcagatatc accatcatgt ttgccggact atggctggtt
    16321 tgcgaagtga gcggactgtc attcctctac atgcacctgt tggtggcgct gattacgctg
    16381 gtggtgttcc agatgttggg cggcatcacc gatttttatc gctcatggcg cggtgttcgg
    16441 gcagcgacag aatttgccct gctgctacaa aactggacct taagcgtgat tttcagcgcc
    16501 ggactggtgg cgttcaacaa tgatttcgat acgcaactga aaatctggct ggcgtggtat
    16561 gggctgacca gcatcggact ggtggtttgc cgttcatgta ttcgcattgg ggcgggctgg
    16621 ctgcgtaatc atggctataa caagcgtatg gtcgcggtgg cgggggattt agccgccgga
    16681 caaatgctga tggagagctt ccgtaatcag ccgtggttag ggtttgaagt ggtgggtgtc
    16741 tatcacgatc cgaaaccggg cggcgtttct aacgactggg cgggcaatct gcaacagctg
    16801 gtcgaggatg cgaaagcggg caagattcat aacgtctata tcgcgatgca aatgtgcgac
    16861 ggcgcgcgag tgaaaaaact ggtccatcaa ttggcggaca ccacctgttc ggtgctgctg
    16921 atccccgacg tctttacctt caacattctc cattcacgtc tcgaagagat gaacggcgtt
    16981 ccggtggtgc cgctgtatga cacgccactt tccggggtaa accgcctgct caaacgtgcg
    17041 gaagacattg tgctggcaac gcttattctg ctgctgatct ccccggtgct gtgctgtatt
    17101 gctctggcgg taaaactcag ttcaccaggg ccggttattt ttcgccagac tcgctacggc
    17161 atggatggca aaccgatcaa agtgtggaag ttccgttcga tgaaagtgat ggagaacgac
    17221 aaagtggtga ctcaggcgac gcagaacgat ccgcgcgtca ccaaagtggg gaactttctg
    17281 cgccgcacct cgctggatga actgccgcag tttatcaatg tgcttaccgg ggggatgtcg
    17341 attgtgggtc cacgtccgca cgcggtggcg cataacgaac agtatcgcca gctcattgaa
    17401 ggctacatgc tgcgccataa agtgaaaccg ggcattaccg gctgggcgca gattaacggc
    17461 tggcgcggcg aaaccgacac gctggagaaa atggaaaaac gcgtcgagtt cgatcttgag
    17521 tacatccgcg aatggagcgt ctggttcgat atcaaaatcg ttttcctgac ggtattcaaa
    17581 ggcttcgtta acaaagcggc atattgatat gagcttacgt gaaaaaacca tcagcggcgc
    17641 gaagtggtcg gcgattgcca cggtgatcat catcggcctc gggctggtgc agatgaccgt
    17701 gctggcgcgg attatcgaca accaccagtt cggtttgctt accgtgtcgc tggtgattat
    17761 cgcgctggca gatacgcttt ctgacttcgg tatcgctaac tcgattattc agcgaaaaga
    17821 aatcagccac cttgaactca ccacgttgta ctggctgaac gtcgggctgg ggatcgtggt
    17881 gtgcgtggcg gtgtttttgt tgagtgatct catcggcgac gtgctgaata acccggacct
    17941 ggcaccgttg attaaaacat tgtcgctggc gtttgtggtg atcccccacg ggcagcagtt
    18001 ccgcgcgttg atgcagaagg agctggagtt caacaaaatc ggcatgatcg aaaccagcgc
    18061 ggtgctggcg ggcttcactt ttacggtggt tagcgcccat ttctggccgc tggcgatgac
    18121 cgcgatcctc ggttatctgg tcaatagtgc ggtaagaacg ctgctgtttg gctactttgg
    18181 ccgcaaaatt tatcgccccg gtctgcactt ctcgctggcg tcggtggcac caaacttacg
    18241 ttttggtgcc tggctgacgg cggacagcat catcaactat ctcaacacca acctttcaac
    18301 gctggtgctg gcgcgtattc tcggcgcggg cgtggcaggg ggatacaacc tggcgtacaa
    18361 cgtggccgtt gtgccgccga tgaaactgaa cccaatcatc acccgcgtgt tgtttccggc
    18421 atttgccaaa attcaggacg acaccgaaaa gctgcgcgtt aacttctaca agctgctgtc
    18481 ggtagtgggg attatcaact ttccggcgct gctggggctg atggtggtgt cgaataactt
    18541 tgtaccgctg gtctttggtg agaagtggaa cagcattatt ccggtgctgc aattgctgtg
    18601 tgtggtgggg ctgctgcgct cagtggggaa cccgattggt tcgctgctga tggcgaaagc
    18661 gcgggtcgat atcagcttta aattcaacgt attcaaaacc tttctgttta ttccggcgat
    18721 tgttattggt gggcagatgg cgggcgcaat tggcgtcacg cttggcttcc tgctggtgca
    18781 gattatcaac accattctga gttacttcgt gatgattaaa ccggtgctcg gttccagtta
    18841 tcgtcagtac atcctgagtt tgtggctgcc gttttatctc tcgctgccga cactggtggt
    18901 cagttatgcg ctgggcctat tgctgaaagg gcaactggcg ctggggatgc tgctggcggt
    18961 gcaaatagcc gcgggcgtgc tggcgtttgt ggtgatgatt gtgctgtcgc gccatccgct
    19021 ggtggtggaa gtgaagcgtc agttttgtcg cagcgaaaaa atgaaaatgc ttttacgggc
    19081 ggggtgagtt gttgttttag gcactggcaa taaaaacaac aacataacct cacctggcat
    19141 caaatttatg aggaaaaaat gaaattactt attctgggca accacacttg cggcaaccgc
    19201 ggcgacagcg ccatcctgcg cggcttactt gatgccatca acatcctcaa tccacacgcc
    19261 gaagtggacg tgatgagccg ctatcctgtc agttcttcct ggctgctcaa ccgcccggta
    19321 atgggcgatc cgctgttcct gcaaatgaaa caacacaaca gcgcggcggg cgttgtcggg
    19381 cgcgttaaaa aagtcctccg tcgccgctac cagcatcagg tattgctctc acgcgtcacc
    19441 gacactggca agctgcgtaa tatcgccatc gcccagggat tcaccgactt cgtgcgcctg
    19501 ctgtcaggtt acgacgccat tattcaggtc ggcggatcgt tttttgtcga tctctatggc
    19561 gtgccgcagt ttgaacacgc gctttgcaca tttatggcga aaaagccgct gtttatgatt
    19621 ggtcacagcg tcggcccctt ccaggatgag caatttaacc aactggcgaa ctacgttttc
    19681 ggtcactgtg acgcgctgat cctgcgcgag tcggttagcc tcgatctaat gaaacgcagc
    19741 aatatcacca ctgcaaaagt ggaacatggc gtcgataccg cgtggctggt cgatcaccac
    19801 acagaagatt tcaccgccag ctatgccgtc caacactggc tggacgttgc cgcacaacag
    19861 aaaacggtgg caattaccct gcgcgaactg gcaccgttcg acaaacgtct cggcaccact
    19921 caacaagcgt atgaaaaagc ctttgccggg gtggtcaatc gaattctcga tgaagggtat
    19981 caggtgattg cgctctccac ctgtacgggc atcgacagtt ataacaaaga cgatcgcatg
    20041 gtggcgctca atctgcgcca gcacatcagc gatcctgccc gttaccacgt agtgatggat
    20101 gaactcaacg atctggaaat gggcaaaatt ctcggagcct gtgaactcac cgtcggtacg
    20161 cgcctgcact ccgccattat ctctatgaat tttgccactc cggcaattgc catcaactac
    20221 gaacataaat ccgccgggat catgcagcag ctggggctgc cagagatggc aattgatatc
    20281 cgtcatttac tggacggcag cctgcaagcg atggttgcgg ataccttagg ccaacttccg
    20341 gcgctgaacg cacgacttag cgaagccgtc agtcgcgaac gtcagatggg aatgcggatg
    20401 gtgcaatctg tgcttgaacg cattggggag gcgaaatgaa ggtcggcttc tttttactga
    20461 aatttccgct gtcgtcggaa accttcgtcc ttaaccaaat cactgcgttt attgatatgg
    20521 gctttgaggt ggagattgtc gcgcttcaaa aaggcgatac agagaacacc cacgcggcat
    20581 ggacgaaata caaccttgcc gccagaaccc gctggttaca ggacgaacct acgggcaaag
    20641 tggcgaaact gcgccaccga gccagtcaga ccttacgcgg cattcatcgt aaaaatacct
    20701 ggcaggcgct taacctcaaa cgctatggcg cagagtcgcg gaacctgatt ttgtctgcca
    20761 tttgctgcca ggtcgcaaca ccgtttcatg ccgatgtgtt tatcgctcat tttggccctg
    20821 ctggggtaac cgcggcaaaa ctccgcgaac tgggtgtcat tcgcggcaaa attgccacta
    20881 tcttccacgg tattgatatc tccagccggg aggtgctcaa ccactacact cccgaatatc
    20941 aacaactgtt tcgccgtggc gacctgatgt taccgataag cgatttgtgg gccggaaggc
    21001 tgcaaaaaat gggctgcccg agggaaaaaa tcgccgtatc gcgcatgggc gtggacatga
    21061 cgcgctttag cccgcgtccg gtgaaagcgc ctgcaacgcc gctggaaatc atttccgtcg
    21121 cacgcttaac cgagaaaaaa ggcctgcatg tggcgatcga agcctgccgt cagttgaaag
    21181 agcagggcgt ggcatttcgc tatcgcatcc tcggcattgg cccgtgggaa cgacgcctgc
    21241 gcaccctcat cgaacaatat caactggaag atgtggtaga gatgccgggc tttaaaccga
    21301 gccatgaagt gaaagcgatc ctcgatgacg cggatgtctt cctgttgcca tcggtaacgg
    21361 gcgcggatgg cgatatggaa ggtattccgg tggcgctgat ggaggcgatg gcggtcggca
    21421 ttccggtggt ttctactctg cacagcggaa taccggaact ggtagaggcc gataaatccg
    21481 gctggctggt gcctgagaac gatgctcgcg cactggcgca acgactggcg gcgtttagcc
    21541 aactggacac cgacgaactg gctccggtcg tcaaacgtgc gcgcgaaaaa gttgaacacg
    21601 attttaacca gcaggtgatc aatcgagaac tcgtcagctt gctgcaagct ttatagagga
    21661 gaacgcatgc catttaaaaa actctcccga cgcaccttcc tgacggcaag ctccgcgctt
    21721 gccttccttc atacgccttt cgcccgagca cttcctgccc ggcaaagcgt taacattaac
    21781 gactacaacc cacacgactg gattgcttca tttaaacaag ccttcagcga agggcaaacg
    21841 gtcgtcgtgc ctgccggatt cgtttgtgac aatatcaaca ccggcatctt cattcctgca
    21901 ggtaaaacgt tacacatcct tggaagcctg cgcggtaacg gcagagggcg atttgtctta
    21961 caggacggca gccaggtgac aggggaggag ggcggcagta tgaataacat cactctggat
    22021 gtgcgcggct ctgactgcac catcaaaggg ctggcgatga gcggctttgg tccggtaacg
    22081 cagatttata tcggcggcaa aaacaaacgg gtcatgcgca acctgaccat cgataacctc
    22141 actgtcagcc acgctaatta cgccatctta cgccagggat ttcataacca gattatcggt
    22201 gccaacatca ccaactgtaa gttcagcgac ttacagggcg acgccattga atggaatgtg
    22261 gcgattaacg accgcgatat tttgatatcc gaccacatca tcgagcgcat caactgtacc
    22321 aacggcaaaa tcaactgggg catcggcata ggccttgcgg gaagcactta cgataataat
    22381 tacccggaag atcaggcagt gaaaaacttt gtcgtggcga atatcacggg atcggattgt
    22441 cgacagttga tccatgttga aaatggtaaa cattttgtta ttcgtaatat caaagcccgc
    22501 aatatcacac cggatttcag taagaaagca ggtattgata acgccacagt cgctatttac
    22561 ggttgtgaca atttcgcaat tgataatatt gaaatgatta atagcgccgg gatgttaatc
    22621 ggctatgggg taattaaagg caaatatctc tcgataccgc aaaatttccg agtgaataat
    22681 attcaactgg ataacaccca ccttgcttac aaattgcgcg gcatccaaat ctccgccggg
    22741 aatgctgtct cctttgtggc gctgactaac attgagatga agcgtgcctc gcttgagctg
    22801 cacaacaagc cgcaacatct ttttatgcgt aatatcaaag tgatgcagga atcctcagtt
    22861 ggacccgcat tgagcatgag cttcgacatg cgcaaagacg tacgaggtgt ttttatggcg
    22921 aaaaaagaaa cactgctgtc acttgcaaat gttcatgcgg tgaatgaaaa aggacaaagc
    22981 tccgtcgata tcgacaggat aaatcaccat attgttaatg tggaaaagat taactttaga
    23041 ttgccggaac ggagggagta gatttgcgac cattcctgga aaaatggagc catacttagg
    23101 aacaatgcta ctgcaatcca caacgaagcg gcgtaacatc acaagtaatt cagtaatcaa
    23161 ttcagggtaa ttgatgctgg cgaaaaaaat cgaacaagct ataattcagc aaccatttta
    23221 caggtggatg aaataatgac gaatttaaaa gcagttattc ctgtagcggg tcttgggatg
    23281 catatgttgc ctgccactaa ggcgattccc aaagagatgc taccgatcgt cgacaagcca
    23341 atgattcagt acatcgttga cgagattgtg gctgcaggga tcaaagaaat cctcctggta
    23401 actcacgctt ccaagaacgc ggtcgaaaac cacttcgaca cctcttatga attagaatct
    23461 ctccttgaac agcgcgtgaa gcgtcaactg ctggcggaag tacagtccat ttgcccgccg
    23521 ggcgtgacca ttatgaacgt gcgtcagggc gaacctttag gtttaggcca ctccattttg
    23581 tgtgcacgac ccgccattgg tgataaccca tttgtcgtgg tgctgccaga cgttgtgatc
    23641 gacgacgcga gtgccgatcc gctgcgttac aaccttgctg ccatgattgc gcgcttcaac
    23701 gaaacgggcc gtagccaggt gctggcaaaa cgtatgccgg gtgacctctc tgaatactcc
    23761 gtcattcaga ccaaagagcc gctggaccgc gaaggtaaag tcagccgcat tgttgaattc
    23821 atcgaaaaac cggatcagcc gcaaacactg gactcagaca tcatggccgt tggtcgctat
    23881 gtgctttctg ccgatatttg gccggaactt gaacgcactc agcctggtgc atggggacgt
    23941 attcaactga ctgatgccat cgctgaactg gcgaaaaaac agtccgttga tgccatgctg
    24001 atgacaggtg acagctacga ctgcggtaaa aaaatgggct atatgcaggc gtttgtgaag
    24061 tatggactgc gcaacctaaa agaaggggcg aagttccgta aaggtattga gaaattgctt
    24121 agcgagtaag tttaaaaaat agacgccctg atagggcgta ataacaaata acggtagtca
    24181 acattcgacg cggtgatgca gatatgcccg gaatgctgat accgtttttt cattctaaaa
    24241 aactcatcat ttcattgagt taactacaaa atttagcact gttttttata atgtttcttc
    24301 ttgtttctgg catcaattgg taagataatt agtgtgtgag tttagaggct ttgcggcaga
    24361 gaagcggagc ttaacacgtc tgtgagagta cgcagtgcac tggtagctgt aaagccagtg
    24421 gcggtagcgt gtttaaataa atacattagt actactgcat attacatcat tgtaggctat
    24481 ttaagcgcta catgttaagc gacagcgcta gcaatcaaat cttttaaagt tacttctcag
    24541 gaatagtaaa atgagcttta atcttgaaaa ttataaaata ggaattattg ggctgggtta
    24601 cgttggctta cctttagctg ttgaatttgg caaaaaaata aagactcttg gttttgatat
    24661 caacgagaaa cggataaaag aattatcagc aggtaatgac tttacgcttg aatgtagttc
    24721 tgatgaactg gctcaagctt actatcttca atattcatgt gattataaag aattagcgac
    24781 ttgcaatgta ttcattgtga cggtacctac tccaattgat gaatataaac aacctgattt
    24841 aacacctctt gttaaagcct cggaaacact cggaaaaata atcaaaaaag atgatattat
    24901 tatctacgaa tcaactgttt atccaggtgc aacagaagaa gtatgtatcc cagtaattga
    24961 gaagatctca ggtctggtat ttaatataga tttttttgcc ggttacagcc cggaacgcat
    25021 taatccgggt gacaaagagc accgcgtgac aacgatcaaa aaagtaactt ctggttcaac
    25081 gcctgaaatt gctgagattg tcgataaatt atatggaacc atcatcaccg ctggaacgca
    25141 taaagcatct tcgatacgtg tggcggaagc ggctaaagtg attgagaaca cccagcgtga
    25201 tttgaatatt gctctgatta acgaacttgc aatgattttc aataagctgg ggattgatac
    25261 ggaggaagta ttaaaagccg caggcactaa atggaacttc ttaccattca gaccaggctt
    25321 agttgggggg cattgcatcg gagttgatcc ctactatttg actcataaag cgcaagcgat
    25381 aggttatcat ccagaagtca tcctggcggg gcgtagaatt aatgatggaa tgagtaaata
    25441 tatagcatca cagttcatta aagccatgct caagaaaaaa ttccaaattg aaggtgctaa
    25501 tgtcttaatt atggggctta cctttaaaga aaactgtccg gatcttcgta atacaaaagt
    25561 tgtagatatc ttggctgaac tgaaagaata caacgtgaac gtggatattt atgatccatg
    25621 ggttgatgtt gaagaagcct actatgagta tggggttaat gtattaaaca cattatctga
    25681 taagaaatat gatggtgtga tctttgcagt tgctcactct caatttaaaa atatgagtaa
    25741 agaagaagtc catggaataa ttagaaatga tggtgttatt tatgatttga aatacatcat
    25801 tgaccctaac ttagtagata ttcgtcttta atcaatactt gatgcaatgt gtcagagagg
    25861 atgcctagtg aaatataaaa aaatagaaga cgctttgtct tctaaatctg aaacatggtt
    25921 gattacaggt gttgcgggat ttatcggttc taacctatta gaggccttac taaaacttaa
    25981 tcaaaaagta gttggcttag ataattttgc aactggacat caagcaaacc ttgatgaggt
    26041 taaagagtct gtttcagctg aacaatggtc tgcttttacc tttgtggaag gagacatatg
    26101 tgagccagag acgtgtgtgg aggttgttaa aggagttgat catgtcctac atcaggctgc
    26161 attaggttct gtgcctcgtt caattaaaga tccaattact acaaataata ccaatatatc
    26221 gggtttcatt aatatgttgg ttgccgccaa agatgccaat gtcagaagtt tcacttacgc
    26281 tgcaagtagc tcaacgtatg gtgatcatcc tgcattacct aaaattgaag aaaatatagg
    26341 taatccgcta tctccatacg cagtgacaaa gtatgtaaat gaattatatg cgcaagtatt
    26401 tgcaagaacc tacggattca aatcaattgg attaagatac tttaatgtat ttggaaaacg
    26461 ccaggatcct aatggggcat atgctgctgt gataccgaag tggactgctg caatgatcaa
    26521 tgatgaaccg ctgtatatca atggtgatgg cgaaacaagt agagactttt gttttattga
    26581 gaatgtcgtg caaatgaata ttcttgctgc acagtctgat gcgtctgcaa gagatcaggt
    26641 ttataacgtt gcagttggtg accgtacgac gc
//
LOCUS       DAPHKZ010000058        26615 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.058, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000058 DAPHKZ010000000
VERSION     DAPHKZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26615
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.058"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            53..1522
                     /gene="gspA"
                     /locus_tag="RH288_002530"
     CDS             53..1522
                     /gene="gspA"
                     /locus_tag="RH288_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspA"
                     /protein_id="HDV4031576.1"
                     /translation="MSTRREVILSWLCEKRQTWRLCYLLGEAGSGKTWLAQQLQKDKH
                     RRVITLSLVVSWQGKAAWIVTDDNAAEQGCRDSAWTRDEMAGQLLHALHRTDSRCPLI
                     IIENAHLNHRRILDDLQRAISLIPDGQFLLIGRPDRKVERDFKKQGIELVSIGRLTEH
                     ELKASILEGQNIDQPDLLLTARVLKRIALLCRGDRRKLALAGETIRLLQQAEQISVFT
                     AKQWRMIYRILGDNRPRKMQLAVVMSGTIIALTCGWLLLSSFTATLPVPAWLIPVTPV
                     VKQDMTKDIAHVVMRDSEALSVLYGVWGYEVPADSAWCDQAVRAGLACKSGNASLQTL
                     VDQNLPWIASLKVGDKKLPVVVVRVGEASVDVLVGQQTWTLTHKWFESVWTGDYLLLW
                     KMSPEGESTITRDSSEEEILWLETMLNRALHISTEPSAEWRPLLVEKIKQFQKSHHLK
                     TDGVVGFSTLVHLWQVAGESAYLYRDEANISPETTVKGK"
     gene            1524..1943
                     /gene="gspB"
                     /locus_tag="RH288_002531"
     CDS             1524..1943
                     /gene="gspB"
                     /locus_tag="RH288_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative general secretion pathway protein GspB"
                     /protein_id="HDV4031577.1"
                     /translation="MFEFYIAAREQKETGHPGIFSRQKHSTIIYVICLLLICLWFAGM
                     VLVGGYARQLWVLWIVKAEVTVEAETPAFKQSTQHYFFKKQPLPVVESVEEEDDPGVA
                     VENAPSSSEDEENTVEESEEKAGLRERVKNALNELER"
     gene            2181..2492
                     /gene="rpsJ"
                     /locus_tag="RH288_002532"
     CDS             2181..2492
                     /gene="rpsJ"
                     /locus_tag="RH288_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDV4031578.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            2525..3154
                     /gene="rplC"
                     /locus_tag="RH288_002533"
     CDS             2525..3154
                     /gene="rplC"
                     /locus_tag="RH288_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDV4031579.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA"
     gene            3165..3770
                     /gene="rplD"
                     /locus_tag="RH288_002534"
     CDS             3165..3770
                     /gene="rplD"
                     /locus_tag="RH288_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDV4031580.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            3767..4069
                     /gene="rplW"
                     /locus_tag="RH288_002535"
     CDS             3767..4069
                     /gene="rplW"
                     /locus_tag="RH288_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDV4031581.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            4087..4908
                     /gene="rplB"
                     /locus_tag="RH288_002536"
     CDS             4087..4908
                     /gene="rplB"
                     /locus_tag="RH288_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDV4031582.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            4925..5203
                     /gene="rpsS"
                     /locus_tag="RH288_002537"
     CDS             4925..5203
                     /gene="rpsS"
                     /locus_tag="RH288_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDV4031583.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            5218..5550
                     /gene="rplV"
                     /locus_tag="RH288_002538"
     CDS             5218..5550
                     /gene="rplV"
                     /locus_tag="RH288_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDV4031584.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            5568..6269
                     /gene="rpsC"
                     /locus_tag="RH288_002539"
     CDS             5568..6269
                     /gene="rpsC"
                     /locus_tag="RH288_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDV4031585.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            6282..6692
                     /gene="rplP"
                     /locus_tag="RH288_002540"
     CDS             6282..6692
                     /gene="rplP"
                     /locus_tag="RH288_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDV4031586.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            6692..6883
                     /gene="rpmC"
                     /locus_tag="RH288_002541"
     CDS             6692..6883
                     /gene="rpmC"
                     /locus_tag="RH288_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDV4031587.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLNEKAGA"
     gene            6883..7137
                     /gene="rpsQ"
                     /locus_tag="RH288_002542"
     CDS             6883..7137
                     /gene="rpsQ"
                     /locus_tag="RH288_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDV4031588.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKL
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            7302..7673
                     /gene="rplN"
                     /locus_tag="RH288_002543"
     CDS             7302..7673
                     /gene="rplN"
                     /locus_tag="RH288_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDV4031589.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGP
                     VTRELRSEKFMKIISLAPEVL"
     gene            7684..7998
                     /gene="rplX"
                     /locus_tag="RH288_002544"
     CDS             7684..7998
                     /gene="rplX"
                     /locus_tag="RH288_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDV4031590.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            8013..8552
                     /gene="rplE"
                     /locus_tag="RH288_002545"
     CDS             8013..8552
                     /gene="rplE"
                     /locus_tag="RH288_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDV4031591.1"
                     /translation="MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            8567..8872
                     /gene="rpsN"
                     /locus_tag="RH288_002546"
     CDS             8567..8872
                     /gene="rpsN"
                     /locus_tag="RH288_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDV4031592.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            8906..9298
                     /gene="rpsH"
                     /locus_tag="RH288_002547"
     CDS             8906..9298
                     /gene="rpsH"
                     /locus_tag="RH288_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDV4031593.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            9311..9844
                     /gene="rplF"
                     /locus_tag="RH288_002548"
     CDS             9311..9844
                     /gene="rplF"
                     /locus_tag="RH288_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDV4031594.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     INLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            9854..10207
                     /gene="rplR"
                     /locus_tag="RH288_002549"
     CDS             9854..10207
                     /gene="rplR"
                     /locus_tag="RH288_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDV4031595.1"
                     /translation="MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            10222..10725
                     /gene="rpsE"
                     /locus_tag="RH288_002550"
     CDS             10222..10725
                     /gene="rpsE"
                     /locus_tag="RH288_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDV4031596.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            10729..10908
                     /gene="rpmD"
                     /locus_tag="RH288_002551"
     CDS             10729..10908
                     /gene="rpmD"
                     /locus_tag="RH288_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDV4031597.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAI
                     RGMINAVSFMVKVEE"
     gene            10912..11346
                     /gene="rplO"
                     /locus_tag="RH288_002552"
     CDS             10912..11346
                     /gene="rplO"
                     /locus_tag="RH288_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDV4031598.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEIRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            11354..12685
                     /gene="secY"
                     /locus_tag="RH288_002553"
     CDS             11354..12685
                     /gene="secY"
                     /locus_tag="RH288_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDV4031599.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            12717..12833
                     /gene="rpmJ"
                     /locus_tag="RH288_002554"
     CDS             12717..12833
                     /gene="rpmJ"
                     /locus_tag="RH288_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDV4031600.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            12980..13336
                     /gene="rpsM"
                     /locus_tag="RH288_002555"
     CDS             12980..13336
                     /gene="rpsM"
                     /locus_tag="RH288_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDV4031601.1"
                     /translation="MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVK
                     ISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPRKPIKK"
     gene            13353..13742
                     /gene="rpsK"
                     /locus_tag="RH288_002556"
     CDS             13353..13742
                     /gene="rpsK"
                     /locus_tag="RH288_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDV4031602.1"
                     /translation="MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            13776..14396
                     /gene="rpsD"
                     /locus_tag="RH288_002557"
     CDS             13776..14396
                     /gene="rpsD"
                     /locus_tag="RH288_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDV4031603.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK"
     gene            14422..15411
                     /gene="rpoA"
                     /locus_tag="RH288_002558"
     CDS             14422..15411
                     /gene="rpoA"
                     /locus_tag="RH288_002558"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDV4031604.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            15452..15835
                     /gene="rplQ"
                     /locus_tag="RH288_002559"
     CDS             15452..15835
                     /gene="rplQ"
                     /locus_tag="RH288_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDV4031605.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKAEAAAE"
     gene            15942..16310
                     /locus_tag="RH288_002560"
     CDS             15942..16310
                     /locus_tag="RH288_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HDV4031606.1"
                     /translation="MWLLDQWAERHIAEAQAKGEFDNLAGSGEPLILDDDSHVPPELR
                     AGYRLLKNAGCLPPELEQRREAIQLLDILKGIRHDDPQYQEVSRRLSLLELKLRQAGL
                     STDFLRGDYADKLLDKINDN"
     gene            16321..16746
                     /gene="zntR"
                     /locus_tag="RH288_002561"
     CDS             16321..16746
                     /gene="zntR"
                     /locus_tag="RH288_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HDV4031607.1"
                     /translation="MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESD
                     LQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQS
                     MQLSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC"
     gene            16802..17020
                     /gene="arfA"
                     /locus_tag="RH288_002562"
     CDS             16802..17020
                     /gene="arfA"
                     /locus_tag="RH288_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor ArfA"
                     /protein_id="HDV4031608.1"
                     /translation="MSRYQHTKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYMRKGK
                     HGNRGNWEASGKKVNHFFTTGLLLSGAC"
     gene            complement(17017..17427)
                     /gene="mscL"
                     /locus_tag="RH288_002563"
     CDS             complement(17017..17427)
                     /gene="mscL"
                     /locus_tag="RH288_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDV4031609.1"
                     /translation="MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL
                     NRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS"
     gene            complement(17557..18933)
                     /gene="trkA"
                     /locus_tag="RH288_002564"
     CDS             complement(17557..18933)
                     /gene="trkA"
                     /locus_tag="RH288_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HDV4031610.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            complement(18955..20244)
                     /gene="rsmB"
                     /locus_tag="RH288_002565"
     CDS             complement(18955..20244)
                     /gene="rsmB"
                     /locus_tag="RH288_002565"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDV4031611.1"
                     /translation="MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALL
                     QELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAET
                     VEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQ
                     WQSIVEANNQRPPMWLRINRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVH
                     ALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLVYATCSVLPEENSLQIKAFLQR
                     TADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK"
     gene            complement(20290..21237)
                     /gene="fmt"
                     /locus_tag="RH288_002566"
     CDS             complement(20290..21237)
                     /gene="fmt"
                     /locus_tag="RH288_002566"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDV4031612.1"
                     /translation="MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVAELQADVMVVVAYGLILPKAVLEM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPIT
                     AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVA
                     TGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV"
     gene            complement(21252..21761)
                     /gene="def"
                     /locus_tag="RH288_002567"
     CDS             complement(21252..21761)
                     /gene="def"
                     /locus_tag="RH288_002567"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDV4031613.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
                     KLDRLKARA"
     gene            21891..23015
                     /gene="dprA"
                     /locus_tag="RH288_002568"
     CDS             21891..23015
                     /gene="dprA"
                     /locus_tag="RH288_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDV4031614.1"
                     /translation="MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGL
                     TLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLLATTDYPGALFVEGEL
                     HALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
                     GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGL
                     SKGVLVVEAALRSGSLVTARCALEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEP
                     EEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDEVTPVDVVAERAGQP
                     VPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV"
     gene            22987..23460
                     /locus_tag="RH288_002569"
     CDS             22987..23460
                     /locus_tag="RH288_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HDV4031615.1"
                     /translation="MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFEREDIYNAL
                     LWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLET
                     REMVIERVLALDNAEFELDDLKWGILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            23489..24031
                     /locus_tag="RH288_002570"
     CDS             23489..24031
                     /locus_tag="RH288_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HDV4031616.1"
                     /translation="MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYV
                     RPLKSSADGHIVKVLEGQVCPACGANLVLRQGRFGMFIGCINYPECEHTELIDKPDET
                     AITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
                     AQGVKHFCASKQCGKPVSAE"
     gene            24036..24608
                     /gene="tsaC"
                     /locus_tag="RH288_002571"
     CDS             24036..24608
                     /gene="tsaC"
                     /locus_tag="RH288_002571"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HDV4031617.1"
                     /translation="MNNNLQRDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVM
                     RLLELKQRPVDKGLILIAANYEQLKPYIDDTMLTDVQRETIFSRWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGA
                     AFPVVPGETGGRLNPSEIRDALTGELFRQG"
     gene            24613..25431
                     /gene="aroE"
                     /locus_tag="RH288_002572"
     CDS             24613..25431
                     /gene="aroE"
                     /locus_tag="RH288_002572"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDV4031618.1"
                     /translation="METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFI
                     NTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLMRLEDGRLLGDNTD
                     GVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAK
                     LFAHTGSIQALSMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKG
                     KTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA"
     gene            25428..25685
                     /locus_tag="RH288_002573"
     CDS             25428..25685
                     /locus_tag="RH288_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HDV4031619.1"
                     /translation="MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRF
                     TGDTPEQWLASFRQHRWDLEEEAENLIQEQSEDDQGWVWLP"
     gene            complement(25661..26215)
                     /locus_tag="RH288_002574"
     CDS             complement(25661..26215)
                     /locus_tag="RH288_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417738.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDV4031620.1"
                     /translation="MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVV
                     IRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGN
                     RVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
                     LRYSANNYVKWKDEYLDQGNQTQP"
BASE COUNT         6801 a         6278 c         6957 g         6579 t
ORIGIN      
        1 catacattat ttttatgatt aaggataatc aataattaaa acaggaagtt ctatgtctac
       61 gagaagagaa gttattcttt cctggttgtg tgagaaacgt caaacctggc gtctatgcta
      121 tttgttgggt gaggctggaa gtggaaaaac ctggctggcg cagcaactgc aaaaagataa
      181 acatcgccgt gtgattactt taagcctcgt tgtttcctgg caaggtaagg ccgcatggat
      241 cgttaccgac gataacgcgg ctgaacaggg ctgccgtgac agcgcctgga cgcgagatga
      301 gatggcgggg caattactgc atgcgcttca tcgaactgat agtcgctgcc ctcttattat
      361 tattgaaaat gctcacctga atcaccgccg catacttgat gatctccaac gcgcaatatc
      421 tcttattcct gacggtcaat ttttgctgat cggcagaccc gatcgaaaag tcgaacgtga
      481 ttttaaaaaa cagggcattg aacttgtctc gataggacgt ctgacggagc acgaacttaa
      541 ggcaagcatc cttgaaggtc agaatattga ccaacccgat ctccttttaa ccgccagagt
      601 tctgaaacgg atagctttat tatgtcgggg cgatcgcaga aagctggcgc ttgccggcga
      661 aacaattcgc ttattacagc aagccgagca gatcagcgtt ttcacagcaa aacaatggcg
      721 aatgatttac cgcatattgg gtgataaccg cccccggaaa atgcagcttg ccgtggtgat
      781 gagtggaacc attatcgctc ttacctgtgg ttggctactg ctgtcctctt ttacagctac
      841 gttacccgtt cctgcgtggc tgatacccgt aacgccagta gttaaacaag atatgactaa
      901 ggatattgct catgtggtga tgcgcgatag tgaggcgcta agcgtgttat acggcgtatg
      961 ggggtacgag gtcccagctg attcggcctg gtgcgatcag gcagtaagag cggggctggc
     1021 atgtaaaagt gggaatgctt ctttacaaac attggtagat cagaatttgc cctggatcgc
     1081 atcgcttaaa gtcggggaca aaaaattgcc tgttgtggtc gttcgcgtcg gtgaggctag
     1141 cgttgatgtc ctcgtaggtc agcaaacgtg gacgctgaca cataaatggt ttgagtcggt
     1201 atggacgggt gattatcttc tgttgtggaa aatgtcgccg gaaggggaga gtaccattac
     1261 gcgtgatagc agcgaggaag agattctctg gctggaaacg atgttaaacc gcgcattgca
     1321 tatttcgaca gaaccttcgg cggagtggcg tcccttgttg gtagaaaaaa taaagcaatt
     1381 tcaaaaaagc caccacttga aaactgacgg tgttgttggc ttttcaacgt tagtacatct
     1441 ctggcaggtg gcaggggaga gtgcctactt atatcgggat gaagcaaata tttccccgga
     1501 aacaacggtg aaggggaaat gacatgtttg aattctatat cgccgcgcgt gagcagaaag
     1561 aaacaggtca ccctggtatc ttctcccgac aaaaacacag caccataata tatgtaattt
     1621 gtttattact gatttgcctg tggtttgcag gaatggtgct ggttggtggg tatgccaggc
     1681 agctatgggt gctttggata gtaaaagccg aagtcactgt agaggctgaa acgcccgctt
     1741 ttaaacaatc aacacaacac tatttcttca aaaaacagcc actccccgtc gtcgaatccg
     1801 tcgaggagga agatgaccca ggcgtcgcgg ttgagaatgc cccctcttct tctgaagacg
     1861 aagaaaatac tgtggaagaa agcgaagaga aagccggttt aagagagcgt gtcaaaaatg
     1921 cactgaacga acttgagaga taacccgaag gctgtttact ttactagcaa tacgcttgcg
     1981 ttcggtggtt aagtatgtat aatgcgcggg cttgtcgtag ttgacagcag gttcaatctg
     2041 aacctcagtt agccgaattt ggctacctaa caatgctccc aatcggggag ctacgtaaga
     2101 acggttacac tctcccatca atcgtaatgg gtctgaggag taatcatttt cgtttataaa
     2161 ataattggag ctctggtctc atgcagaacc aaagaatccg tatccgcctg aaagcgtttg
     2221 atcatcgtct gatcgatcaa gcaaccgcgg aaatcgtcga gactgccaag cgcactggtg
     2281 cgcaggtccg tggtccgatc ccgctgccga cacgcaaaga gcgcttcact gttctgatct
     2341 ccccgcacgt caacaaagac gcgcgcgatc agtacgaaat ccgtactcac ttgcgtctgg
     2401 ttgacatcgt tgagccaacc gagaaaaccg ttgatgctct gatgcgtctg gatctggctg
     2461 ccggtgtaga cgtgcagatc agcctgggtt aatcaggtca ttgagcgatt gagaggttga
     2521 aacaatgatt ggtttagtcg gtaaaaaagt gggtatgacc cgtatcttca cagaagacgg
     2581 cgtttctatc ccagtaaccg taatcgaagt tgaagcaaac cgcgttactc aggttaaaga
     2641 cctggctaac gatggctacc gtgctattca ggtgaccacc ggtgctaaaa aagctaaccg
     2701 tgtgaccaag cctgaagctg gccacttcgc taaagctggc gtagaagctg gccgtggtct
     2761 gtgggaattc cgcctggctg aaggcgaaga gttcactgta ggtcagagca ttagcgttga
     2821 actgtttgct gacgttaaaa aagttgacgt aactggcacc tctaaaggta aaggtttcgc
     2881 aggtaccgtt aagcgctgga acttccgtac ccaggacgct actcacggta actccttgtc
     2941 tcaccgcgtt ccgggttcta tcggtcagaa ccagactccg ggcaaagtgt tcaaaggcaa
     3001 gaaaatggca ggtcagatgg gtaacgaacg tgtaaccgtt cagagccttg acgtagtacg
     3061 cgttgacgct gagcgcaacc tgctgctggt taaaggtgct gtcccgggtg caaccggtag
     3121 cgacctgatc gttaaaccag ctgtgaaggc gtaaggagat agcaatggaa ttagtattga
     3181 aagacgcgca gagcgcgctg actgtttccg aaactacctt cggtcgtgat ttcaacgaag
     3241 cgctggttca ccaggttgtt gttgcttatg cagctggtgc tcgtcagggt actcgtgctc
     3301 agaagactcg tgctgaagta actggttccg gtaaaaaacc gtggcgccag aaaggcaccg
     3361 gccgtgcgcg ttctggttct atcaagagcc cgatctggcg ttctggtggc gtgacctttg
     3421 ctgctcgtcc gcaggaccac agtcaaaaag ttaacaagaa gatgtaccgc ggcgcgctga
     3481 aaagcatcct gtccgaactg gtacgtcagg atcgtctgat cgttgtcgag aagttctctg
     3541 tagaagcgcc gaaaactaag ctgctggcac agaaactgaa agacatggct ctggaagatg
     3601 tgctgatcat caccggtgag ctggacgaaa acctgttcct ggctgcgcgc aacctgcaca
     3661 aggttgacgt acgcgatgca actggtatcg acccggttag cctgatcgcc ttcgacaaag
     3721 tcgtaatgac tgctgatgct gttaagcaag ttgaggagat gctggcatga ttcgtgaaga
     3781 acgtctgctg aaggtgctgc gtgcaccgca cgtttctgaa aaagcgtcta ctgcgatgga
     3841 aaaatccaac accatcgtac tcaaagttgc taaagacgcg accaaagcag aaatcaaagc
     3901 tgctgtgcag aaactgtttg aagtcgaagt cgaagtcgtt aacaccctgg tagttaaagg
     3961 gaaagttaaa cgtcacggac agcgtatcgg tcgtcgtagc gactggaaaa aagcttacgt
     4021 caccctgaaa gaaggccaga atctggactt cgttggcggc gctgagtaag tcggaggagt
     4081 aatacaatgg cagttgttaa atgtaaaccg acatctccgg gtcgtcgcca cgtagttaaa
     4141 gtggttaacc ctgagctgca caagggcaaa ccttttgctc cgttgctgga aaaaaacagc
     4201 aaatccggtg gtcgtaacaa caatggccgt atcaccactc gtcatatcgg tggtggccac
     4261 aagcaggctt accgtattgt tgacttcaaa cgcaacaaag acggtatccc ggcagttgtt
     4321 gaacgtcttg agtacgatcc gaaccgttcc gcgaacatcg cgctggttct gtacaaagac
     4381 ggtgaacgcc gttacatcct ggcccctaaa ggcctgaaag ctggcgacca gattcagtct
     4441 ggcgttgatg ctgcaatcaa accaggtaac accctgccga tgcgcaacat cccggttggt
     4501 tctactgttc ataacgtaga aatgaaacca ggtaaaggcg gtcagctggc acgttccgct
     4561 ggtacttacg ttcagatcgt tgctcgtgat ggtgcttatg tcaccctgcg tctgcgttct
     4621 ggtgaaatgc gtaaagtaga agcagactgc cgtgcaactc tgggcgaagt tggcaatgct
     4681 gagcatatgc tgcgcgttct gggtaaagca ggtgctgcac gctggcgtgg tgttcgtccg
     4741 accgttcgcg gtaccgcgat gaacccggta gaccacccac atggtggtgg tgaaggtcgt
     4801 aactttggta agcacccggt aactccgtgg ggcgttcaga ccaaaggtaa gaagacccgc
     4861 agcaacaagc gtactgataa attcatcgta cgtcgccgta gcaaataatt ttagaggata
     4921 agccatgcca cgttctctca agaaaggtcc ttttattgac ctgcacttgc tgaagaaggt
     4981 agagaaagcg gtggaaagcg gagacaagaa gcccctgcgc acttggtccc gtcgttcaac
     5041 gatctttcct aacatgatcg gtttgaccat cgctgtccat aatggtcgtc agcacgttcc
     5101 ggtatttgta accgacgaaa tggttggtca caaactgggt gaattcgcac cgactcgtac
     5161 ttatcgcggc cacgctgctg ataaaaaagc gaagaagaaa taaggtagga ggaagagatg
     5221 gaaactatcg ctaaacatcg ccatgctcgt tcttctgctc agaaggttcg ccttgttgct
     5281 gacctgattc gcggtaagaa agtgtcgcag gctctggata ttttgaccta caccaacaag
     5341 aaagcggctg tactggtcaa gaaagttctg gaatctgcca ttgctaacgc tgaacacaac
     5401 gatggcgctg acattgacga tctgaaagtt acgaaaattt tcgtagacga aggcccgagc
     5461 atgaagcgca ttatgccgcg tgcaaaaggt cgtgcagatc gcatcctgaa gcgcaccagc
     5521 cacatcactg tggttgtgtc cgatcgctga gactctggag actagcaatg ggtcagaaag
     5581 tacatcctaa tggtattcgc ctgggtattg taaaaccatg gaactctacc tggtttgcga
     5641 acaccaaaga attcgctgac aacctggaca gcgattttaa agtacgtcag tacctgacta
     5701 aggaactggc taaagcgtcc gtatctcgta tcgttatcga gcgtccggct aagagcatcc
     5761 gtgtaaccat tcacactgct cgcccgggta tcgttatcgg taaaaaaggt gaagacgtag
     5821 aaaaactgcg taaggtcgta gcggacatcg ctggcgttcc tgcacagatc aacatcgccg
     5881 aagttcgtaa gcctgaactg gacgcaaaac tggttgctga cagcatcact tctcagctgg
     5941 aacgtcgcgt tatgttccgt cgtgctatga agcgtgctgt acagaacgca atgcgtctgg
     6001 gcgctaaagg tattaaagtt gaagttagcg gccgtctggg cggcgcggaa atcgcacgta
     6061 ccgaatggta ccgcgaaggt cgcgtaccgc tgcacactct gcgtgctgac atcgactaca
     6121 acacctctga agcgcacacc acttacggtg taatcggcgt taaagtgtgg atcttcaaag
     6181 gcgagatcct gggtggtatg gctgctgttg aacaaccgga aaaaccggct gctcagccta
     6241 aaaagcagca gcgtaaaggc cgtaaataag gagcgtcgct gatgttacaa ccaaagcgta
     6301 caaaattccg taaaatgcac aaaggccgta accgcggtct ggcgcagggt acggatgtta
     6361 gcttcggcag cttcggtctg aaagctgttg gccgtggtcg tctgactgcc cgtcagatcg
     6421 aagcagcacg tcgtgctatg acccgtgcag ttaagcgtca aggtaagatc tggatccgtg
     6481 tgttcccgga caaaccgatc actgaaaagc cgctggcagt gcgtatgggt aaaggtaaag
     6541 gtaacgtgga gtattgggtt gccttgattc agccgggtaa agtcctgtat gaaatggacg
     6601 gtgttccgga agagctggcc cgtgaagcat tcaagctggc agcagcgaaa ctgccgatta
     6661 aaaccacctt tgtaactaag acggtgatgt aatgaaagca aaagagctgc gtgagaagag
     6721 cgttgaagag ctgaacaccg agctgctgaa cctgctgcgt gagcagttca acctgcgtat
     6781 gcaggctgca agtggccagc tgcaacagtc tcacctgttg aagcaagtgc gtcgcgatgt
     6841 cgcacgcgtt aagactttac tgaacgagaa ggcgggtgcg taatgaccga taaaatccgt
     6901 actctgcaag gtcgcgttgt tagcgacaaa atggagaaat ccattgttgt tgctatcgaa
     6961 cgttttgtga aacacccgat ctacggtaaa ttcatcaagc gtacgaccaa actgcacgta
     7021 catgacgaga acaacgaatg cggtatcggt gacgtggttg aaatccgcga atgccgtccg
     7081 ctgtccaaga ctaaatcctg gacgctggtt cgcgttgtag agaaagcggt tctgtaatac
     7141 agtacactct ctcaatacga ataaacggct cagaaatgag ccgtttattt tttctaccca
     7201 tatccttgaa gcggtgttat aatgccgcgc cctcgatatg gggattttta acgacctgat
     7261 tttcgggtct cagtagtagt tgacattagc ggagcactaa aatgatccaa gaacagacta
     7321 tgctgaacgt cgccgacaac tccggtgcac gtcgcgtaat gtgtatcaag gttctgggtg
     7381 gctcgcaccg tcgctacgca ggcgtaggcg acatcatcaa gatcaccatc aaagaagcaa
     7441 ttccgcgtgg taaggtcaaa aaaggtgatg tgctgaaggc ggtagtggtg cgcaccaaga
     7501 agggtgttcg tcgcccggac ggttctgtca ttcgcttcga tggtaatgct tgtgttcttc
     7561 tgaacaacaa cagcgagcag cctatcggta cgcgtatttt tgggccggta actcgtgagc
     7621 ttcgtagtga gaagttcatg aaaattatct ctctggcacc agaagtactc taaggagcga
     7681 atcatggcag cgaaaatccg tcgtgatgac gaagttatcg tgttaaccgg taaagataaa
     7741 ggtaaacgcg gtaaagttaa gaatgtcctg tcttccggca aggtcattgt tgaaggtatc
     7801 aacctggtta agaaacatca gaagccggtt ccggccctga accaaccggg tggcatcgtt
     7861 gaaaaagaag ccgctattca ggtttccaac gtagcaatct tcaatgcggc aaccggcaag
     7921 gctgaccgtg taggctttag attcgaagac ggtaaaaaag tccgtttctt caagtctaac
     7981 agcgaaacta tcaagtaatt tggagtagta cgatggcgaa actgcatgat tactacaaag
     8041 acgaagtagt taaaaaactc atgactgagt ttaactacaa ttctgtcatg caagtccctc
     8101 gggtcgagaa gatcaccctg aacatgggtg ttggtgaagc gatcgctgac aaaaaactgc
     8161 tggataacgc tgcagcagac ctggcagcaa tctccggtca aaaaccgctg atcaccaaag
     8221 cacgcaaatc tgttgcaggc ttcaaaatcc gtcagggcta tccgatcggc tgtaaagtaa
     8281 ctctgcgtgg cgaacgcatg tgggagttct ttgagcgcct gatcactatt gctgtacctc
     8341 gtatccgtga cttccgtggc ctgtccgcta agtctttcga cggtcgtggt aactacagca
     8401 tgggtgtccg tgagcagatc atcttcccag aaatcgacta cgataaagtc gaccgcgttc
     8461 gtggtttgga tattaccatt accactactg cgaaatctga cgaagaaggc cgcgctctgc
     8521 tggctgcctt tgacttcccg ttccgcaagt aaggtagggt tactaaatgg ctaagcaatc
     8581 aatgaaagca cgcgaagtaa aacgcgtagc tttagctgat aaatacttcg cgaaacgcgc
     8641 tgaactgaaa gcgatcatct ctgatgtgaa cgcttccgac gaagatcgtt ggaacgctgt
     8701 tctcaagctg cagactctgc cgcgtgattc cagcccgtct cgtcagcgta accgctgccg
     8761 tcaaacaggt cgtccgcatg gtttcctgcg gaagttcggg ttgagccgta ttaaggtccg
     8821 tgaagccgct atgcgcggtg aaatcccggg tctgaaaaag gctagctggt aattgtcacc
     8881 aattgaatca cgggagtaaa gacagatgag catgcaagat ccgatcgcgg atatgctgac
     8941 ccgtatccgt aacggtcagg ccgcgaacaa agctgcggtc accatgcctt cctccaagct
     9001 gaaagtggca atcgccaacg tgctgaagga agaaggtttt attgaagatt ttaaagttga
     9061 aggcgacacc aagcctgaac tggaacttac tctgaagtat ttccagggca aagctgttgt
     9121 agaaagcatt cagcgtgtca gccgcccagg tctgcgcatc tataaacgta aagatgagct
     9181 gccgaaagtt atggcgggtc tgggtatcgc agttgtttct acctctaaag gtgttatgac
     9241 tgatcgtgca gcgcgccagg ctggtcttgg tggcgaaatt atctgctacg tagcctaatc
     9301 ggaggaaaaa atgtctcgtg ttgctaaagc accggtcgtt gttcctgccg gcgttgacgt
     9361 aaaaatcaac ggtcaggtta ttacgatcaa aggtaaaaac ggcgagctga ctcgtactct
     9421 caacgatgct gttgaagtta aacatgcaga taataccctg accttcggtc cgcgtgatgg
     9481 ttacgcagac ggttgggcac aggctggtac cgcgcgtgcc ctgctgaact caatggttat
     9541 cggtgttacc gaaggcttca ctaagaagct gcagctggtt ggtgtaggtt accgtgcagc
     9601 ggttaaaggc aatgtgatta acctgtctct gggtttctct catcctgttg accatcagct
     9661 gcctgcgggt atcactgctg aatgtccgac tcagactgaa atcgtgctga aaggcgctga
     9721 taagcaggtg atcggccagg ttgcagcgga tctgcgcgcc taccgtcgtc ctgagcctta
     9781 taaaggcaag ggtgttcgtt acgccgacga agtcgtgcgt accaaagagg ctaagaagaa
     9841 gtaaggtaac actatggata agaaatctgc tcgtatccgt cgtgcgaccc gcgcacgccg
     9901 caagctccag gagctgggcg caactcgcct ggtggtacat cgtaccccgc gtcacattta
     9961 cgcacaggta attgcaccga acggttctga agttctggta gctgcttcta ctgtagaaaa
    10021 agctatcgct gaacaactga agtacaccgg taacaaagac gcggctgcag ctgtgggtaa
    10081 agctgtcgct gaacgcgctc tggaaaaagg catcaaagat gtatcctttg accgttccgg
    10141 gttccaatat catggtcgtg tccaggcact ggcagatgct gcccgtgaag ctggccttca
    10201 gttctaaggt agaggtgtaa gatggctcac atcgaaaaac aagctggcga actgcaggaa
    10261 aagctgatcg cggtaaaccg cgtatctaaa accgttaaag gtggtcgtat tttctccttc
    10321 acagctctga ctgtagttgg cgatggtaac ggtcgcgttg gttttggtta cggtaaagcg
    10381 cgtgaagttc cagcagcgat ccagaaagcg atggaaaaag cccgtcgcaa tatgattaac
    10441 gtcgcgctga ataacggcac tctgcaacac cctgttaaag gtgttcacac gggttctcgc
    10501 gtattcatgc agccggcttc cgaaggtacc ggtatcatcg ccggtggtgc aatgcgcgcc
    10561 gttctggaag tcgctggggt tcataacgtt ctggctaaag cctatggttc caccaacccg
    10621 atcaacgtgg ttcgtgcaac tattgatggc ctggaaaata tgaattctcc agaaatggtc
    10681 gctgccaagc gtggtaaatc cgttgaagaa attctgggga aataaaccat ggcaaagact
    10741 attaaaatta ctcaaacccg cagtgcaatc ggtcgtctgc cgaaacacaa ggcaacgctg
    10801 cttggcctgg gtctgcgtcg tattggtcac accgtagagc gcgaggatac tcctgctatt
    10861 cgcggtatga tcaacgcggt ttccttcatg gttaaagttg aggagtaaga gatgcgttta
    10921 aatactctgt ctccggccga aggctccaaa aaggcgggta aacgcctggg tcgtggtatc
    10981 ggttctggcc tcggtaaaac cggtggtcgt ggtcacaaag gtcagaagtc tcgttctggc
    11041 ggtggcgtac gtcgcggttt cgagggtggt cagatgcctc tgtaccgtcg tctgccgaaa
    11101 ttcggcttca cttctcgtaa agcagcgatt acagccgaaa ttcgtctgtc tgacctggct
    11161 aaagtagaag gcggtgtagt agacctgaac acgctgaaag cggctaacat tatcggtatc
    11221 cagatcgagt tcgcgaaagt gatcctggct ggcgaagtaa cgactccggt aactgttcgt
    11281 ggcctgcgtg ttactaaagg cgctcgtgct gctatcgaag ctgctggcgg taaaatcgag
    11341 gaataagtag cagatggcta aacaaccggg attagatttt caaagtgcca aaggtggctt
    11401 aggcgagctg aaacgcagac tgctgtttgt tatcggtgcg ctgattgtgt tccgtattgg
    11461 ctcttttatt ccgatccctg gtattgatgc cgctgtactt gccaaactgc ttgagcaaca
    11521 gcgaggcacc atcattgaga tgtttaacat gttctctggt ggtgctctca gccgtgcttc
    11581 tatctttgct ctggggatca tgccgtatat ttcggcgtcg atcattatcc agctactgac
    11641 ggtggttcac ccaacgttgg cagaaattaa gaaagaaggg gagtctggtc gtcgtaagat
    11701 cagccagtac acccgctacg gtactctggt gctggcaata ttccagtcga tcggtattgc
    11761 taccggtctg ccgaatatgc ctggtatgca aggcctggtg attaacccgg gctttgcatt
    11821 ctacttcacc gctgttgtaa gtctggtcac aggaaccatg ttcctgatgt ggttgggcga
    11881 acagattact gaacgaggta tcggcaacgg tatttcaatc attatcttcg ccggtattgt
    11941 cgcgggactc ccgccagcca ttgcccatac tatcgagcaa gcgcgtcaag gcgacctgca
    12001 cttcctcgtg ttgctgttgg ttgcagtatt agtatttgca gtgacgttct ttgttgtatt
    12061 tgttgagcgt ggtcaacgcc gcattgtggt aaactacgcg aaacgtcagc aaggtcgtcg
    12121 tgtctatgct gcacagagca cacatttacc gctgaaagtg aatatggcgg gggtaatccc
    12181 ggcaatcttc gcttccagta ttattctgtt cccggcgacc atcgcgtcat ggttcggggg
    12241 cggtactggt tggaactggc tgacaacaat ttcgctgtat ttgcagcctg ggcaaccgct
    12301 ttatgtgtta ctctatgcgt ctgcaatcat cttcttctgt ttcttctaca cggcgttggt
    12361 tttcaacccg cgtgaaacag cagataacct gaagaagtcc ggtgcatttg taccaggaat
    12421 tcgtccggga gagcaaacgg cgaagtatat cgataaagta atgacccgcc tgaccctggt
    12481 tggtgcgctg tatattacct ttatctgcct gatcccggag ttcatgcgtg atgcaatgaa
    12541 agtaccgttc tacttcggtg ggacctcact gcttatcgtt gttgtcgtga ttatggactt
    12601 tatggctcaa gtgcaaactc tgatgatgtc cagtcagtat gagtctgcat tgaagaaggc
    12661 gaacctgaaa ggctacggcc gataattggt cgcccgagaa gttacggaga gtaaaaatga
    12721 aagttcgtgc ttccgtcaag aaattatgcc gtaactgcaa aatcgttaag cgtgatggtg
    12781 tcatccgtgt gatttgcagt gccgagccga agcataaaca gcgccaaggc tgattttttc
    12841 gcatattttt cttgcaaagt tgggttgagc tggctagatt agccagccaa tcttttgtat
    12901 gtctgtgcgt ttccatttga gtatcctgaa aacgggcttt tcagcatgga acgtacatat
    12961 taaatagtag gagtgcatag tggcccgtat agcaggcatt aacattcctg atcataagca
    13021 tgccgtaatc gcattaactt cgatttatgg cgtcggcaag acccgttcta aagccatcct
    13081 ggctgcagcg ggtatcgctg aagatgttaa gatcagtgag ctgtctgaag gacaaatcga
    13141 cacgctgcgt gacgaagttg ccaaatttgt cgttgaaggt gatctgcgcc gtgaaatcag
    13201 catgagcatc aagcgcctga tggatcttgg ttgctatcgc ggtttgcgtc atcgtcgtgg
    13261 tctcccggtt cgcggtcagc gtaccaagac caacgcacgt acccgtaagg gtccgcgcaa
    13321 accgatcaag aaataatcgg ggtgattgaa taatggcaaa ggcaccaatt cgtgcacgta
    13381 aacgtgtaag aaaacaagtc tctgacggcg tggctcatat ccatgcttct ttcaacaaca
    13441 ccatcgtgac tatcactgat cgtcagggta acgcgttggg ttgggcaaca gccggtggtt
    13501 ccggtttccg tggttctcgc aaatccactc cgtttgcagc tcaggttgca gcagagcgtt
    13561 gcgctgacgc cgtgaaagaa tacggcatca agaatctgga agttatggtt aaaggtccgg
    13621 gtccaggccg cgaatctact attcgtgctc tgaacgccgc aggtttccgc atcactaaca
    13681 ttactgatgt gactccgatc cctcataacg gttgtcgtcc gccgaaaaaa cgtcgcgtat
    13741 aacgcctcgt tttccaggtt tgttggagaa agaaaatggc aagatatttg ggtcctaagc
    13801 tcaagctgag ccgtcgtgag ggcaccgact tattccttaa gtctggcgtt cgcgcgatcg
    13861 ataccaagtg taaaattgaa caagctcctg gccagcacgg tgcgcgtaaa ccgcgtctgt
    13921 ctgactatgg tgtgcagttg cgtgaaaagc aaaaagttcg ccgtatctat ggtgtgctgg
    13981 agcgtcagtt ccgtaactac tacaaagaag cagcacgtct gaaaggcaac accggtgaaa
    14041 acctgttggc tctgctggaa ggtcgtctgg acaacgttgt ataccgtatg ggcttcggtg
    14101 ccactcgtgc agaagcacgt cagctggtta gccataaagc aattatggta aacggtcgtg
    14161 ttgttaacat cgcttcttat caggttagtc cgaatgacgt tgtaagcatt cgtgagaaag
    14221 cgaagaagca gtctcgcgtg aaagccgctc tggagctggc tgagcagcgt gaaaagccaa
    14281 cctggctgga agttgatgct ggcaagatgg aaggtacgtt taagcgtaag ccggagcgtt
    14341 ctgatctgtc tgcggacatt aacgaacacc tgatcgtcga gctttactcc aagtaaagct
    14401 tagtaccaaa gagaggacac aatgcagggt tctgtgacag agtttctaaa accgcgcctg
    14461 gttgatatcg agcaagtgag ttcgacgcac gccaaggtga cccttgagcc tttagagcgt
    14521 ggctttggcc atactctggg taacgcactg cgccgtattc tgctctcatc gatgccgggt
    14581 tgcgcggtga ccgaggttga gattgatggt gtactacatg agtacagcac caaagaaggc
    14641 gttcaggaag atatcctgga aatcctgctc aacctgaaag ggctggcggt gagagttcag
    14701 ggcaaagatg aagttattct taccttgaat aaatctggca ttggccctgt gactgcagcc
    14761 gatatcaccc acgacggtga tgtcgaaatc gtcaagccgc agcacgtgat ctgccacctg
    14821 accgatgaga acgcgtctat tagcatgcgt atcaaagttc agcgcggtcg tggttatgtg
    14881 ccggcttcta cccgaattca ttcggaagaa gatgagcgcc caatcggccg tctgctggtc
    14941 gacgcatgct acagccctgt ggagcgtatt gcctacaatg ttgaagcagc gcgtgtagaa
    15001 cagcgtaccg acctggacaa gctggtcatc gaaatggaaa ccaacggcac aatcgatcct
    15061 gaagaggcga ttcgtcgtgc ggcaaccatt ctggctgaac aactggaagc tttcgttgac
    15121 ttacgtgatg tacgtcagcc tgaagtgaaa gaagagaaac cagagttcga tccgatcctg
    15181 ctgcgccctg ttgacgatct ggaattgact gtccgctctg ctaactgcct taaagcagaa
    15241 gctatccact atatcggtga tctggtacag cgtaccgagg ttgagctcct taaaacgcct
    15301 aaccttggta aaaaatctct tactgagatt aaagacgtgc tggcttcccg tggactgtct
    15361 ctgggcatgc gcctggaaaa ctggccaccg gcaagcatcg ctgacgagta accggatcac
    15421 aggttaaggt tttactgaga aggataaggt catgcgccat cgtaagagtg gtcgtcaact
    15481 gaaccgcaac agcagccatc gccaggctat gttccgcaat atggcaggtt cactggttcg
    15541 tcatgaaatc atcaagacga ctctgcctaa agcgaaagag ctgcgccgcg tagttgagcc
    15601 gctgattact cttgccaaga ctgatagcgt tgctaatcgt cgtctggcat tcgcccgtac
    15661 tcgtgataac gagatcgtgg caaaactgtt taacgaactg ggcccgcgtt tcgcgagccg
    15721 tgccggtggt tacactcgta ttctgaagtg tggcttccgt gcaggcgaca acgcgccgat
    15781 ggcttacatc gagctggttg atcgttcaga gaaagcagaa gctgctgcag agtaatctga
    15841 agcaacgtaa aaaaacccgc cccggcgggt ttttttatac ccgtagtatc cccacttatc
    15901 tacaatagct gtactctttt tgttcatccc ctggagtatt tatgtggtta cttgaccagt
    15961 gggcagagcg ccatatagca gaagcgcaag cgaaaggtga gtttgataac ctggcaggta
    16021 gcggcgaacc attgatactg gatgatgatt ctcacgtgcc accggaatta cgtgcggggt
    16081 atcgcttgct gaagaatgcc ggttgcttac cgccagaact tgagcaacgg agagaagcaa
    16141 ttcagcttct ggatattctc aaaggtatcc gtcacgatga tccgcaatat caagaggtta
    16201 gccgtcgatt gtcattactg gaattgaagc tgcgacaagc tggattgagt accgattttt
    16261 tacgcggcga ttatgctgac aagttgttgg acaaaatcaa cgataactag tggagtatgt
    16321 atgtatcgca ttggtgagct ggcaaaaatg gcggaagtaa cacccgacac gattcgttat
    16381 tacgaaaaac agcagatgat ggagcatgaa gtgcgtactg aaggtgggtt tcgcctatat
    16441 accgaaagcg atctccagcg attgaaattt atccgccatg ccagacaact aggtttcagt
    16501 ctggagtcga tccgcgagtt gctgtcgatc cgcatcgatc ctgaacacca tacctgtcag
    16561 gagtcaaaag gcattgtgca ggaaagattg caggaagtcg aagcacggat agccgagttg
    16621 cagagtatgc agctttcctt gcaacgcctt aacgatgcct gttgtgggac tgctcatagc
    16681 agtgtttatt gttcgattct tgaagctctt gaacaagggg cgagtggcgt taagagtggt
    16741 tgttgatttt ttgcactggc aggattacac tcgcgccgtt aaataaccaa ctggagtttt
    16801 tatgagtcga tatcagcata ctaaagggca gataaaggat aatgcgatag aagcattact
    16861 acatgatccc ttattccgac agcgcgtaga gaaaaataag aaggggaaag gcagttacat
    16921 gcgaaaagga aaacatggca atcgggggaa ctgggaggcc agtggcaaga aagtaaatca
    16981 cttttttacc actggtcttc tgctttcagg cgcttgttaa gagcggttat tctgctcttt
    17041 cagcaaatca cgaatttctg tcagtaatac ttcttcttta gttggtgcag gtgcggctgc
    17101 tggttcttct tttttccgat tcagtttgtt gattagctta atcgccataa agatggcaaa
    17161 ggccacaatc agaaaatcaa agacgttttg aatgaagaca ccgtaatgca tcacaacagc
    17221 agggatatcc ccctgcgcat cgcgtagcgt gacagcaaac tgtttaaaat cgatcccgcc
    17281 aattaataag cccagaggag gcatgatgat atcggcaacc agtgaagaga caatcttccc
    17341 gaatgccgca ccgataatga cacccaccgc caaatccacc acgttcccgc gcatcgcaaa
    17401 ttcgcgaaat tctttaataa tgctcatgtt attctcccta tgaagccgac aaccataagt
    17461 ctaacaaatg ttaagccatt ttcctgccag gaatgaattt aattaatcct tgataatcaa
    17521 agggaaataa taaggcgtca ttagacgcct tattaattac aagaagaaag ggcttggctg
    17581 gaagagtctt tcgacgtcgg taataaactt tttatctgtg aggaacataa ttacgtgatc
    17641 gccttgctca atgcgcagat tgtcattggc aatcatcacg tcgtttccac gtaccaccgc
    17701 tccaataatc gttcctggcg gtagcttgat ttcgtcaatg actctgccga caacgcgtga
    17761 ggtgctttca tcaccgtgag caacggcttc aatagcttct gctacgccgc ggcgcaatga
    17821 ggaaacacca acaatatctg cttttcgcac atggctaagc aacgcagaaa tagttgcttg
    17881 ttgtggtgaa atcgcaatat cgataacgct cccctgaacc agatccacat aagcgcgacg
    17941 ctggatcaat accatcacct ttttcgcacc catacgtttg gcaagcatgg cggacatgat
    18001 attggcctcg tcatcgttgg tgacggcaat aaacagatca acttgatcga tatgttcttc
    18061 ggccagtagt tcttgatccg acgcatcacc aaaaaagacg atcgtattct gtaacttttc
    18121 cgccagttcg gcagcgcgct gctgattacg ttcgatgagt ttaacgctgt aatctttttc
    18181 cagacgacgc gccagccctg caccgatatt accgccacca accagcatga tccgcttata
    18241 cggtttttcc agtcgctgta attcactcat caccgcgcgg atatgctgtg aagcggcaat
    18301 aaagaacact tcatcaccag cttcaacaat ggtcgaacct tgcggacgaa tggggcgatc
    18361 gtggcggaaa attgctgcca cacgagtatc gatatgtggc atatgttcgc gcatggtcga
    18421 aagtgcatta ccaatcagcg ggccgccata ataggcttta accacagcca ggctgacttt
    18481 accctcagcg aagttcacca cctgcaatgc gccgggatac tcaatcagtc ggtaaatatt
    18541 atcgataacc aactgctctg gtgcgatcag atgatcaatc ggcacagcat ctgaatgaaa
    18601 tagcttatcg gcatcgcgca cgtagtctgg tgagcggata cgagcgatgc gattaggggt
    18661 gttgaaaagt gagtaggcta cctggcaggc aaccatattg gtttcatctg aactggttac
    18721 agcaaccagc atatcggcgt cgtcggcacc tgcctcccgc aatacgcgtg gatgagagcc
    18781 atgcccctgc acgacccgca ggtcaaattt atcctgtaag gtccgcagac gctcaccgtt
    18841 ggtatcgaca acagtaatat cgttgttctc gccaaccagg ttttccgcca gtgtgccgcc
    18901 aacctggccg gcacccagaa tgataatttt catcagtcgc gacccgttat ctcatcactt
    18961 tttgattagc ttagcgtaaa agaagccgtc gccctcttcg gcaccaggta gattttgttt
    19021 acccggttgc tctggtgttc ctgtttcgca aagttcggca tcagcggtac gttgcaaaaa
    19081 ggctttaatc tgcaggctat tctcttccgg taacaccgaa caggtggcat agaccagagt
    19141 tccaccggtt tttaaatgcg gccaaatggc gtcgagaatt tcagactgca attgcgcgag
    19201 ttccgggata tcgcgatcgc gacgtaacca tttaatatct ggatggcgac gaatcacacc
    19261 ggttgctgaa caaggcgcat ctaataaaat gcgatcaaac tgttgctcgc cacaccattg
    19321 agaagggtaa cggccatcac cttgtttcac ggtcgccttc ataccaaggc gttttaaatt
    19381 gtcgtaaacc cgagagaggc gctgttcgtc gatatcaacc gcaacaacct gcgcttctgg
    19441 tgccacctca aggatatgcg ttgttttacc gccgggggcg gcacaaagat ccaaaatgtg
    19501 ttcaccgttt tgtggcgcaa gccaggtcat gcaaccttgt gctgatgcat cctgaacggt
    19561 aacccatccg tcttcaaaac caggtagcgc atgaacaggt gcaggtgttt ccagacgtac
    19621 agcatcaggg taatccgcat gcgggaaacc tttcattcct gcttcatcca gcaatgcaag
    19681 ccagctgtcg cgggaatgat gcgtacgatt aatacgcagc cacattggcg gacgctggtt
    19741 attggcttcg acgatggatt gccactgctc tggatacgct ttttgcagac gcttcagcaa
    19801 ccaggaagga tgcagataac gtgcatcact ggcattaaac tcggctaata actcttcttg
    19861 ctgacgctgg aactggcgta atacaccgtt tatcaaccct ttaagttgcg gacgcttaat
    19921 tgcgatagcg ccttcaaccg tttcagccag cgcagcatga ggtggaatgc gggtataaag
    19981 cagttgatac aaaccaacca taatcaggta atgcacggtc cgctgtttgc cggtcatcgg
    20041 acgggccatt aacttattaa tcagccagtc taactgcgaa agcgtacgca gtacgccaaa
    20101 gcacaactct tgaagaagtg ctttgtcttt atcggaaact ttttgctgga gcggtggcag
    20161 aatgttgctt aatgattgcc cttgctcgac gacttgttca acggcctggg ccgccatgct
    20221 acgtaaatta cgttgttttt tcataagtat aaaaacgccc ggcaagaccg ggcttagaag
    20281 agtggactat cagaccagac ggttgcccgg aacaaaccat tcccgacgag agttcaggag
    20341 gtcttgcgcg ctcatcgctt tcttacccgc aggttgtaac gagagcaggt tcaggatgcc
    20401 atcaccagtc gcaacctgaa tgccttgttt gttggcttca aggatcgttc ctggtgcagc
    20461 gttggttgcc gtatcaatga ccgatgcttt ccagacttta accggctgtc cttcaatttc
    20521 cagccagctc attggccatg gattgaaagc gcgaatgcag cgttcaagct gtgctgccga
    20581 aagtgaccag tcaatacgcg cttcttcttt actcaacttc tcggcgtaag tgacaagagt
    20641 ttcgtcctga acttctggtt tcgccgtgcc gtctgccagt tgtttcaacg tggtgataag
    20701 cccttgtggg ccaagctctg ccagcttgtc gtacagcgta ccactggtat cttctgcagt
    20761 aatcgggcag gagagcttat agagcatatc accggtgtct aaaccgacat ccatttgcat
    20821 aatggtcaca ccagtttctg catcacccgc ccatagtgag cgttggattg gtgcagcacc
    20881 gcgccagcgt ggcagcagtg aaccatgaac gttgatacag ccaagacgcg gcatctccag
    20941 cactgctttc ggcagaatta aaccataggc gacgacgacc ataacatcag cctgcagttc
    21001 ggcgaccagt tgctggtttt cttgtggacg cagggaaaca ggttgaaaaa cgggcagacc
    21061 tttttcctca gccagaactt taaccgggct gggcatcagt tttttaccgc gtcctgccgg
    21121 tcggtctggc tgggtgaaca cgccaacgac gttatgacca gaagacaaca gcgcgtcgag
    21181 atgacgcgct gcaaagtcag gtgtacccgc aaaaataata cgtagtgatt ctgacacgtt
    21241 agttcttatc cttaagcccg ggctttcaga cgatccagtt tttcaacttt ctgacgaata
    21301 cgttgttgtt tcagcggtga cagataatcc ataaacagtt tgccgaccag gtgatccatc
    21361 tcatgctgaa tacagatggc taacagaccg tctgcttcca gttcaaatgg tttaccgtcg
    21421 cggtcaaggg cgcgaatttt aactttctct gcgcgcggca ctaaagcacg ttgttcaggg
    21481 atcgacaggc aaccttcttc aatgcctgtt tcgccgcttt tttctaaaag ctctggattg
    21541 attaacacta gccgttcgtc acggttttcc gaaacatcaa taacaatgat acgttgatgg
    21601 atatcaacct gggttgccgc caggccaata ccttcttctg cgtacatcgt ctcgaacata
    21661 tcatcgacga tacgctgaat ttctgcattc acttcttcta ccggtttagc aactttgcga
    21721 agccgctcgt ccggaatatg taacacttgc aaaactgaca taaatctcca gagatgtgtt
    21781 caggagttag aaagattatt tcttctattc tagacaaatc cccctctgat tgacagcatc
    21841 actgaccaat cgcaaagatt gctaaggctg cttatggcag ggagataagg atggtcgata
    21901 cagaaatttg gctgcgttta atgagtatca gcagcttgta cggcgatgat atggtccgta
    21961 tcgctcactg ggtggcaaaa cagtcgcata ttgatgcggt tgtattgcag caaacagggc
    22021 ttacattgcg gcaggcacaa cgctttcttt catttccacg aaagagtatc gaaagctcac
    22081 tttgttggtt ggagcaaccc aaccatcatt taattcctgc ggacagcgaa ttttatcctc
    22141 ctcaacttct ggcgacgaca gattaccccg gcgcactgtt tgttgaagga gaactgcacg
    22201 cgctgcattc atttcagctt gccgtagtgg ggagtcgggc gcattcatgg tatggcgagc
    22261 gatggggacg attattttgc gaaactctgg cgacgcgtgg agtgacaatt acgagtggac
    22321 tggcgcgtgg aatcgatggt gtagcgcata aagcagcctt acaggtaaat ggcgtcagca
    22381 ttgctgtatt ggggaatgga cttaatacca ttcatccccg ccgtcatgcc cgactggctg
    22441 ccagtctgct tgaacagggg ggcgctctcg tctcggaatt tcccctcgat gttccacccc
    22501 ttgcttacaa tttcccacga agaaatcgca ttatcagtgg tctaagtaaa ggtgtactgg
    22561 tggtggaagc ggctttgcgt agtggttcgc tggtgacagc acgttgtgcg cttgagcagg
    22621 ggcgagaagt ttttgccttg ccaggtccaa tagggaatcc gggaagcgaa gggcctcact
    22681 ggttaataaa acaaggtgcg attcttgtga cggaaccgga agaaattctg gaaaacttgc
    22741 aatttggatt gcactggttg ccagacgccc ctgaaaattc attttattca ccagatcagc
    22801 aagacgtggc attgccattt cctgagctcc tggctaacgt aggagatgag gtaacacctg
    22861 ttgacgtcgt cgctgaacgt gccggccaac ctgtgccaga ggtagttact caactactcg
    22921 aactggagtt agcaggatgg atcgcagctg tacccggcgg ctatgtccga ttgaggaggg
    22981 catgccatgt tcgacgtact aatgtatttg tttgaaacct atattcacac agaagctgag
    23041 ttgcgtgtgg atcaagacaa acttgaacag gatcttaccg acgcaggttt tgagcgagaa
    23101 gatatctaca atgccctgct atggctggaa aaacttgctg attatcagga agggttggca
    23161 gaaccgatgc aactggcctc ggatcctctc tccatgcgta tttatacacc ggaagagtgt
    23221 gaacgactgg atgccagctg ccgtgggttt ctgcttttcc ttgagcagat tcaggtgctc
    23281 aaccttgaaa ctcgtgaaat ggtgatagag cgagtgctcg cgctggataa cgcagagttc
    23341 gaactggatg atctgaaatg ggggatcctg atggtgttgt tcaatattcc gggctgcgaa
    23401 aatgcgtacc agcaaatgga agaattactc tttgaagtga atgaaggtat gctgcattaa
    23461 tcatttcttt aattcagcat aagttgttat ggcgaaatca gcactgttca cggtgcgtaa
    23521 taatgagtcc tgcccaaagt gcggggctga actggttatt cgatccggga aacacggtcc
    23581 gtttcttgga tgctcacagt atccggcgtg tgactacgtc cgtcctctga aatcttcagc
    23641 ggatggacat atcgtcaaag ttctggaggg gcaggtttgc cctgcatgtg gcgcaaatct
    23701 ggtattacgc cagggacgct ttggtatgtt tattggttgc attaactacc ctgaatgcga
    23761 acataccgaa cttatcgata aaccggacga aacagcaatt acatgccccc aatgtcggac
    23821 gggccatctg gtccagcgcc gctcccgtta tggcaaaaca tttcactctt gtgatcgcta
    23881 cccggagtgt caatttgcca ttaacttcaa acccatagct ggagaatgcc ctgagtgtca
    23941 ttatccgcta ctcatcgaaa agaaaaccgc gcagggtgta aaacactttt gtgccagtaa
    24001 acaatgtgga aagccggttt cggcggaata ataacgtgaa taataacctg caaagagacg
    24061 ctatcgcagc tgcgatagat gttctcaatg aagaacgtgt catcgcctat ccaacggaag
    24121 ccgttttcgg tgttgggtgc gatcctgata gcgaaacagc agtgatgcga ctgttggagt
    24181 taaaacagcg tccggttgat aaggggctga ttttaatcgc agcaaattac gagcagctta
    24241 aaccctatat tgatgacacc atgttgactg acgtgcagcg tgaaaccatt ttttcccgct
    24301 ggccaggtcc tgtcaccttt gtctttcccg cgcctgcgac aacaccgcgc tggttgacgg
    24361 gccgctttga ttcgcttgct gtacgagtca ccgaccatcc gttggtggtt gctttgtgcc
    24421 aggcttatgg taaaccgctg gtttctacca gtgccaactt gagtggattg ccaccttgtc
    24481 gaacagtaga cgaagttcgc gcacaatttg gcgcggcgtt cccggttgtg cctggtgaaa
    24541 cgggggggcg tttaaatcct tcagaaatcc gcgatgccct gacgggtgaa ctgtttcgac
    24601 aggggtaaca taatggaaac ctatgctgtt tttggtaatc cgatagccca cagcaaatcg
    24661 ccattcattc atcagcaatt tgctcagcaa ctgaatattg aacatcccta tgggcgcgtg
    24721 ttggcaccca tcaatgattt catcaacaca ctgaacgctt tctttagtgc tggtggtaaa
    24781 ggtgcgaatg tgacggtgcc ttttaaagaa gaggcttttg ccagagcgga tgagcttact
    24841 gaacgggcag cgttggctgg tgctgttaat accctcatgc ggttagaaga tggacgcctg
    24901 ctgggtgaca ataccgatgg tgtaggcttg ttaagcgatc tggaacgtct gtcttttatc
    24961 cgccctggtt tacgtattct gcttatcggc gctggtggag catctcgcgg cgtactactg
    25021 ccactccttt ccctggactg tgcggtgaca ataactaatc ggacggtatc ccgcgcggaa
    25081 gagttggcta aattgtttgc gcacactggc agtattcagg cgttgagtat ggacgaactg
    25141 gaaggtcatg agtttgatct cattattaat gcaacatcca gtggcatcag tggtgatatt
    25201 ccggcgatcc cgtcatcgct cattcatcca ggcatttatt gctatgacat gttctatcag
    25261 aaaggaaaaa ctccttttct ggcatggtgt gagcagcgag gctcaaagcg taatgctgat
    25321 ggtttaggaa tgctggtggc acaggcggct catgcctttc ttctctggca cggtgttctg
    25381 cctgacgtag aaccagttat aaagcaattg caggaggaat tgtccgcgtg aatcaggcca
    25441 tccagtttcc ggacagggaa gagtgggacg agaataaaaa atgtgtatgt tttcccgctc
    25501 tcgtgaatgg tatgcaactg acatgcgcga tctctggcga gagtctggcg tatcgcttta
    25561 ctggagatac gccagaacag tggttagcga gttttcgtca gcatcgctgg gacctggaag
    25621 aagaagcgga aaacttaatt caggaacaaa gtgaagatga tcaaggctgg gtctggttac
    25681 cctgatccag atattcgtcc ttccatttca cgtaattatt cgcggaatag cgtaacccag
    25741 ccttctcttc atcacttaac gggcggatct gtttgacggg gctaccgaga tacagatatc
    25801 cgctctccag ccgtttattt tgtgggacca gactacccgc accaatcatc acatcatctt
    25861 ctactattgc gccatcaagt aaaattgagc ccatcccaac caaaactcga ttgccaatgg
    25921 tgcagccgtg gagcatcacc ttgtgaccaa cagtgacatc ttcgccaatg gttaatgggt
    25981 tgccatctgg gttgtacgag gatttatgag tgacatgcaa catactgcca tcctggatat
    26041 tggtgcgtgc tccgatctgt acataatgta catctccacg aatcacaacg agcggccaga
    26101 tccccacatc atcagccaga cgaacgtcac caatcacgac actgctatcg tcgatcatta
    26161 cgcgctgacc gatttgtgga aaaagatcgc ggtatgggcg taaaacatca gacatactta
    26221 cctcagcaat aaatgattta ctaatgactt tgggggcatt attggccttg tgcaagtctt
    26281 ttagtatgca aaaaagcacc gttttgtgtg cgattgcagc aaaaagggtg aaaaaacaac
    26341 aaacagaaaa aaagatcaaa aaaatacttg tgcaaaaaat tgggatccct ataatgcgcc
    26401 tccgttgaga cgacaacgtg aaacacttca caggatggtc ggaacaacga agagaaaaaa
    26461 atcctgaaat tcagggttga ctctgaaaga ggaaagcgta atatacgcca cctcgcgaca
    26521 gtgagctgaa agccgcgtcg caactgctct ttaacaattt atcagacaat ctgtgtgggc
    26581 actcgaagat acggattctt aacgtcgcaa gacga
//
LOCUS       DAPHKZ010000059        26004 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.059, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000059 DAPHKZ010000000
VERSION     DAPHKZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26004
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.059"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            316..1614
                     /gene="kgtP"
                     /locus_tag="RH288_002575"
     CDS             316..1614
                     /gene="kgtP"
                     /locus_tag="RH288_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoglutarate permease"
                     /protein_id="HDV4031621.1"
                     /translation="MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFC
                     SLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCM
                     MCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGF
                     YASFQYVTLIGGQLLALLVVVVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQL
                     DETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGM
                     HANVASGIMTAALFVFMLIQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVS
                     SPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYV
                     ALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL"
     gene            complement(1611..1934)
                     /locus_tag="RH288_002576"
     CDS             complement(1611..1934)
                     /locus_tag="RH288_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HDV4031622.1"
                     /translation="MRILFVCSLLLLSGCSHMANDSWSGQDKAQHFIASAMLSAAGNE
                     YSQHQGMSRDRSAMFGLMFSVSLGASKELWDSRPEGSGWSWKDLAWDVAGASTGYTVW
                     QLTRH"
     gene            complement(1980..3335)
                     /gene="pssA"
                     /locus_tag="RH288_002577"
     CDS             complement(1980..3335)
                     /gene="pssA"
                     /locus_tag="RH288_002577"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HDV4031623.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKI
                     ASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLF
                     RQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNL
                     PAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHD
                     PQLELAPQREKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            complement(3449..6109)
                     /gene="pat"
                     /locus_tag="RH288_002578"
     CDS             complement(3449..6109)
                     /gene="pat"
                     /locus_tag="RH288_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HDV4031624.1"
                     /translation="MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVLAWPDIASLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSA
                     PASQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVS
                     NTILDWAQQRKMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLRGDRLMIISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPEHV
                     AISNPLDLRDDASSEHYIKTLDILLHSQDFDALMVIHSPSAAAPATESAQVLIEAVKH
                     HPRSKYVSLLTNWCGEHSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIASDSTE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQA
                     RVHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEDQAVVALPPLNMN
                     LARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASG
                     SEFTALDVTLDISPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQ
                     QFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTR
                     AISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVA
                     LARKLGFNVDIQLEEGIVGLTLNLAQREES"
     gene            complement(6141..6839)
                     /gene="tapT"
                     /locus_tag="RH288_002579"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             complement(6141..6839)
                     /gene="tapT"
                     /locus_tag="RH288_002579"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417078.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HDV4031625.1"
                     /translation="MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCS
                     TITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSQDLLELVQNP
                     DYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
                     VDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTGAAAGLGEHFTRFKTRYLAGKT
                     QHLGSITAEQLESV"
     gene            complement(6908..7327)
                     /gene="trxC"
                     /locus_tag="RH288_002580"
     CDS             complement(6908..7327)
                     /gene="trxC"
                     /locus_tag="RH288_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HDV4031626.1"
                     /translation="MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRF
                     GIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL"
     gene            7534..8571
                     /locus_tag="RH288_002581"
     CDS             7534..8571
                     /locus_tag="RH288_002581"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HDV4031627.1"
                     /translation="MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRA
                     DGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSFIDPEVLRR
                     QRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS
                     SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGV
                     LLGEWWRQNKA"
     gene            complement(8619..9308)
                     /gene="ung"
                     /locus_tag="RH288_002582"
     CDS             complement(8619..9308)
                     /gene="ung"
                     /locus_tag="RH288_002582"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDV4031628.1"
                     /translation="MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPG
                     FTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPI
                     DWMPVLPAESE"
     gene            9613..9996
                     /gene="grcA"
                     /locus_tag="RH288_002583"
     CDS             9613..9996
                     /gene="grcA"
                     /locus_tag="RH288_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HDV4031629.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVV
                     AVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            complement(10052..10639)
                     /gene="eamB"
                     /locus_tag="RH288_002584"
     CDS             complement(10052..10639)
                     /gene="eamB"
                     /locus_tag="RH288_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HDV4031630.1"
                     /translation="MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLA
                     GMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQA
                     KPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCW
                     ALAGHLFQRLFRQYGRQLNIVLALLLVYCAVHIFY"
     gene            10742..11623
                     /locus_tag="RH288_002585"
     CDS             10742..11623
                     /locus_tag="RH288_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417072.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4031631.1"
                     /translation="MDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFS
                     VQLFEKIGRRMCLTREGKKLLPHIYELTRVMDTLREAAKKESDPDGELRVVSGETLLS
                     YRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVFYRVGNDDALNRRELG
                     EQSLVLVASPQIADVDFTEPGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIEL
                     ISIESIKRCVAANIGVSYLPRFAVAKELECGELIELPFGEQSQTITAMCAHHAGKAVS
                     PAMHTFIQCVEESFVAG"
     gene            complement(11832..13166)
                     /gene="srmB"
                     /locus_tag="RH288_002586"
     CDS             complement(11832..13166)
                     /gene="srmB"
                     /locus_tag="RH288_002586"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HDV4031632.1"
                     /translation="MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNC
                     YLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHVFNFDMPRSGDTYLH
                     RIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTG
                     KPSKKVLAKRAEKKKAKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE"
     gene            13298..14035
                     /gene="trmN"
                     /locus_tag="RH288_002587"
     CDS             13298..14035
                     /gene="trmN"
                     /locus_tag="RH288_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HDV4031633.1"
                     /translation="MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAG
                     VKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHT
                     ADIQQWITQQTVRFDLIISNPPYYQQGVECSTPQREQARYTTTLDHPSLLTCAAECIT
                     EEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGPDQNYSEAYTALTQAFYLFM"
     gene            complement(14020..15642)
                     /gene="nadB"
                     /locus_tag="RH288_002588"
     CDS             complement(14020..15642)
                     /gene="nadB"
                     /locus_tag="RH288_002588"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDV4031634.1"
                     /translation="MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEG
                     STFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGV
                     LFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALNHPNIRVLERS
                     NAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTR
                     FMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLG
                     LGIDLTQEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAEDITRRMPYAHDISTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPELLTHSGPSILSPGNHYINR"
     gene            15898..16053
                     /gene="rseD"
                     /locus_tag="RH288_002589"
     CDS             15898..16053
                     /gene="rseD"
                     /locus_tag="RH288_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HDV4031635.1"
                     /translation="MIRLQHDKQKQMRYGTLQKRDTLTLCLLKLQLMEWRFDSAWKFG
                     LGRLYLG"
     gene            16050..16625
                     /gene="rpoE"
                     /locus_tag="RH288_002590"
     CDS             16050..16625
                     /gene="rpoE"
                     /locus_tag="RH288_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HDV4031636.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            16658..17308
                     /gene="rseA"
                     /locus_tag="RH288_002591"
     CDS             16658..17308
                     /gene="rseA"
                     /locus_tag="RH288_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HDV4031637.1"
                     /translation="MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMR
                     GDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
                     GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            17308..18264
                     /gene="rseB"
                     /locus_tag="RH288_002592"
     CDS             17308..18264
                     /gene="rseB"
                     /locus_tag="RH288_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HDV4031638.1"
                     /translation="MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYE
                     LSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKA
                     KFSWTPTWLPQGFSEVSSSRRPLPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQM
                     LRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ"
     gene            18261..18740
                     /gene="rseC"
                     /locus_tag="RH288_002593"
     CDS             18261..18740
                     /gene="rseC"
                     /locus_tag="RH288_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HDV4031639.1"
                     /translation="MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFAS
                     DVAALCGAILGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSSEDASQ"
     gene            18938..20737
                     /gene="lepA"
                     /locus_tag="RH288_002594"
     CDS             18938..20737
                     /gene="lepA"
                     /locus_tag="RH288_002594"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDV4031640.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLR
                     KGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTL
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPA
                     VNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            20753..21727
                     /gene="lepB"
                     /locus_tag="RH288_002595"
     CDS             20753..21727
                     /gene="lepB"
                     /locus_tag="RH288_002595"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDV4031641.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGD
                     SLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
                     VSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETK
                     ENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGLRLSRIGGIH"
     gene            21999..22679
                     /gene="rnc"
                     /locus_tag="RH288_002596"
     CDS             21999..22679
                     /gene="rnc"
                     /locus_tag="RH288_002596"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDV4031642.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            22676..23581
                     /gene="era"
                     /locus_tag="RH288_002597"
     CDS             22676..23581
                     /gene="era"
                     /locus_tag="RH288_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDV4031643.1"
                     /translation="MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLREGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
                     NVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            23593..24321
                     /gene="recO"
                     /locus_tag="RH288_002598"
     CDS             23593..24321
                     /gene="recO"
                     /locus_tag="RH288_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDV4031644.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     TLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
                     TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTHYE"
     gene            24333..25064
                     /gene="pdxJ"
                     /locus_tag="RH288_002599"
     CDS             24333..25064
                     /gene="pdxJ"
                     /locus_tag="RH288_002599"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HDV4031645.1"
                     /translation="MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVT
                     TEGGLDVAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYA
                     DAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAI
                     IGRAVMTGLKDAVAEMKRLMLEARG"
     gene            25064..25444
                     /gene="acpS"
                     /locus_tag="RH288_002600"
     CDS             25064..25444
                     /gene="acpS"
                     /locus_tag="RH288_002600"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDV4031646.1"
                     /translation="MAILGLGTDIVEIARIEAVIARSGDRLARRVLSDNEWAIWKTHH
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKL
                     GVANMHVTLADERHYACATVIIES"
     gene            25865..25945
                     /gene="shoB"
                     /locus_tag="RH288_002601"
     CDS             25865..25945
                     /gene="shoB"
                     /locus_tag="RH288_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin ShoB"
                     /protein_id="HDV4031647.1"
                     /translation="MTDCRYLIKRVIKIIIAVLQLILLFL"
BASE COUNT         6368 a         6497 c         6862 g         6277 t
ORIGIN      
        1 gcgaaaggcc atcctgacgg atggcctttt tgcattggcg cagaaaaaaa tgcctgatgc
       61 gacgctgcgc gtcttatact cccacatatg ccagattcag caacggatac ggcttcccca
      121 acttgcccac ttccatacgt gtcctcctta ccagaaattt atccttaagc tcctcaataa
      181 ccattttcct gctaactaaa ttcatggtta aggttgcata atgatatgca acaaatgtat
      241 aacatttcct ttaccaaaaa aaataaacaa aagcgaccga caaaagcatc ggattacggc
      301 aggagacata atggcatggc tgaaagtact gtaacggcag acagcaaact gacaagtagt
      361 gatactcgtc gccgcatttg ggcgattgtg ggggcctctt caggtaatct ggtcgagtgg
      421 ttcgatttct atgtctactc gttctgttca ctctactttg cccacatctt cttcccttcc
      481 gggaacacga cgactcaact actacaaaca gcaggtgttt ttgctgcggg attcctgatg
      541 cgcccaatag gcggttggct atttggccgc atagccgata aacatggtcg caaaaaatcg
      601 atgctgttat cggtgtgtat gatgtgtttc ggatcgctgg ttatcgcctg cctcccaggt
      661 tatgaaacta taggtacgtg ggctccggca ttattgcttc tcgctcgttt atttcaggga
      721 ttatctgttg gcggagaata tggcaccagc gccacctata tgagtgaagt tgccgttgaa
      781 gggcgcaaag gtttttacgc atcatttcag tatgtgacgt tgatcggcgg acaactgcta
      841 gccctactgg ttgtcgtggt tttacaacac accatggaag acgctgcact cagagagtgg
      901 ggatggcgta ttcctttcgc gttaggagct gtgttagctg ttgtggcgtt gtggttacgt
      961 cgtcagttag atgaaacttc gcaacaagaa acgcgcgctt taaaagaagc tggatctctg
     1021 aaaggattat ggcgcaatcg ccgtgcattc atcatggttc tcggttttac cgctgcgggc
     1081 tccctttgtt tctatacctt cactacttat atgcagaagt atctggtaaa tactgcggga
     1141 atgcatgcca acgtggcgag tggcattatg actgccgcat tgtttgtatt catgcttatt
     1201 caaccactca ttggcgcgct gtcggataag attggtcgcc gtacctcaat gttatgtttc
     1261 ggttcgctgg cagccatttt taccgttcct attctctcag cattgcaaaa cgtttcctcg
     1321 ccttatgccg cttttggtct ggtgatgtgt gccctgctga tagtgagttt ttatacatca
     1381 atcagtggaa tactgaaggc tgagatgttc ccggcacagg ttcgcgcatt aggcgttggt
     1441 ctgtcatatg cggtcgctaa tgctatattt ggtggttcgg cggagtacgt agcgttgtcg
     1501 ctgaaatcaa taggaatgga aacagccttc ttctggtatg tgaccttgat ggccgtggtg
     1561 gcgtttctgg tttctttgat gctacatcgc aaagggaagg ggatgcgtct ttagtgacgg
     1621 gtcagttgcc agacggtata gccggtgctt gcaccggcga catcccaggc caaatccttc
     1681 cagctccagc cgctcccttc ggggcggcta tcccaaagct cttttgacgc ccccaaactg
     1741 acagagaaca tcaatccaaa catggcactg cgatcccggc tcatcccctg atgctgtgaa
     1801 tattcatttc cggcggcgga aagcatcgcc gaggcgataa agtgttgagc tttatcctgc
     1861 ccgctccagc tatcgttagc catatggctg catccagaaa gtaacaatag cgaacagaca
     1921 aaaagaatac gcaaaacgtg gcctccaaaa aacaaacccc gtacaggacg gggttgtgat
     1981 tacaggatgc ggctaattaa tcggtcgatg cggatacggc gcaaacggcg gatgagttta
     2041 cgaaccttca ccggataatc ggcaatactt tgcagatcgc gatagtgctt aacgatggtg
     2101 gtatgctcgc ggatcagctc cagttctttc tctcgctgtg gcgccagctc aagttgcgga
     2161 tcgtggatca aaatggcgtt ttccagatcc agacgccagg cgcgcgggtt caggttatta
     2221 ccggtgatca acatccactt atcatcaacc cacatccctt tcaggtgata ggtgttgtcg
     2281 tcatctttcc ataaccgaac cactagctgg tcagtattga cgtaatactg caaacggctc
     2341 aggaaacgac gcagattgat ctcatagaga taaggcaatg cgccaattat cttgaaaggt
     2401 tcatcttccg gaatgtagaa gtcattcgcg gttttatcac caacaataat ttcgaccttt
     2461 ttcccttcgc gcagcaactg gataatattg cgcacaagga ttgctggcag gttgaagtat
     2521 ggcgtacaga tggttagttt ctgctcggca caaggcataa gatggaaaat ggtcttgttc
     2581 aacagactcg atttccccag ccccactagc ggcgttacag aaagctgatc gttgtcggca
     2641 tcgccctgga aatgataagc ggcatcacgc agctcctggc ggaacagacg aatatcgttc
     2701 ttgatttccg ggctttttgg ccgattaaca tcatccagac gattaacgcc gcggccattc
     2761 ataatattct gtgtaaccca ttcaaacata atgtctgaca tcttacggtt acggatcaga
     2821 tgataacggt cgtagcgata tttatcgtgc tgatgcaggt aaacatcgtt caggctggca
     2881 ccgctataaa gtacgctatc gtcgatgata aagcctttaa agtgcagaac accaagggct
     2941 tcacgagtat tgattggaac gccataaacc ggaacatcta cgcccggatt ttcctgcgcc
     3001 atgcggcagt accagtcagc gttagtgtta gatgccgcag cgccaatgcg tccacgttgt
     3061 gcacgatgcc agtcgaccag cacccgcaca tccagttccg gacgctgcct tttagcctca
     3121 tacaacgcgt tcagaatgcc tttgccaccg tcatcctgtt cgagatacag ggcgacaatg
     3181 caaatgcgct gcttcgcgct ggctattttt tccagcagcg tctcccggaa gtcggcggga
     3241 gcgtaaaaga aatcgacatc atcaactgat tgagaaatct tgggtagttg ggcaaggtgt
     3301 tgttgatgtt tattacgctt aaattttgac aacatcacag tgcatttctt ctctgttcat
     3361 tgaagggtcc tctgtgcaat gcagacgaca taagcgggca ataataacac cagtcccgat
     3421 taagtggtca acatttccag taccttactc atgattcctc gcgctgggca agatttagcg
     3481 taagcccaac gatcccctct tcgagctgga tatcaacgtt aaacccgagc ttgcgggcta
     3541 gcgccaccat gccacgattg tttggcatcg taataccatt cagacgttgt agtccgtgat
     3601 ctcgcgtata ggtaatcaac ttttccatta agcgtcgacc taagcctaac cctttgagat
     3661 ccgagcgaac cagtacagca aattcggcat cgatgttatc aggatcggaa atcgcacgcg
     3721 tgacgccgag gatctcttcc gtttgatcaa tacgtcgtac cgctacaaac gccatttccc
     3781 gatcgtagtc gatctgtgtc atgttggcta aatcttcatg ggtaaattcg ttgatctcgc
     3841 taaagtagcg gtaataaaga tcttctttgg tgactcgcga aatgaattgc tgaagttgtg
     3901 gctcatcttc tggcaaaatc gggcggaaca agcagcgttc accgtttttc aattctaccc
     3961 attcttccag ctgatgcgga taagggcgca ctgccagccg actctcgtta tcgccttcaa
     4021 acggcgagat atccagcgtg acatccagcg cggtaaattc actgccagaa gccagcaaag
     4081 gatgaatatc cagacgctga atttccgggc aatcgacaat caagttggaa acctgcacca
     4141 gaagctggct caagcctgca acatccaatg ggcgtagcgc actgcgcgca cgaatctttt
     4201 tacttttgat cccctgaata accagatagc gggccaggtt catgttcagc ggcggcagtg
     4261 cgacgacggc ttgatcttca ggacgccact ccacaccgcc ttcacccagc atgatcaacg
     4321 gcccgaaaac cggatcgtgc tcaaccacaa cccgcaactc ctgagcgcca gcacggttag
     4381 ccatactttg caccaacagg ccgtggaccc gcgcctgtgg ccaggccatt tttacgcgat
     4441 cgaaaatagc gttcgccgct tgctggactt cattggctgt acgcaggtaa agcatgacgc
     4501 cctgaacttc cgatttatgt ggaatatccg gcgaacgcaa tttcagcgcc accggataac
     4561 caatctgttc ggcaatatgc accgcttcgg tgctatcgct ggcaatccag gtagggagcg
     4621 tgttcatgcc atacgcttgc aggatgggct gaacttcatg ggtatcgagc gacgtagccc
     4681 cttcggcaat cgcctgttgc aacagaagat gcgcttctgc ggtattggaa gtcagattgc
     4741 tgggcaacgc cggcgtttcg cgtagttgct tctgattacg ccggtactcc accatatgca
     4801 taaaagcagt gatggttcct tccggggtac ggtaggtcgg cagcccggct tcgctgaata
     4861 aacgtcgtgc ctcttgcgag gagtgctcgc cgcaccagtt cgtcagcaaa gagacatatt
     4921 tgctgcgggg atgatgcttt accgcttcaa ttaatacttg cgcgctttct gttgcgggag
     4981 cagcggcgct gggcgaatga ataaccatca gcgcgtcaaa atcctggctg tggagcagaa
     5041 tatccagcgt tttaatatag tgctcactgc tggcgtcatc gcgtagatcg agcgggttag
     5101 atattgccac atgttctggc agtgcatcgc gcagtttctg gcaggtttct tcgcttagcg
     5161 ttgccagctt gccattgcgt gaccataagg catccagcgc cagcgcggca ggcgcagcac
     5221 cgttgctgat aatcatcagc cggtcgccac gtagcgggcg catatggcta agggtttcca
     5281 ccgccgaaaa cagctcgtgg gtgtcctgta cccgcaacaa accggcacgc tgaatagccg
     5341 catcccatgc cgggtccatt cctgccgtcg tgttgagcag tcgctgtgcc gccgggctac
     5401 gtccgctttt aatcaccaga atcggtttat tacgcgaggc actacgggcc gccgaaacaa
     5461 agcgtcgcgc gtcgcttaac tgttcgagat agagcaggat ggcgctggtt ttactgtcgc
     5521 gtgccagata gtcaagcaat tcatcaacgt cgatatccag gctgtcgccg agcgcaataa
     5581 agtaggaaaa gcccatctta cgctgttgcg cccagtcgag gatggtgttg gagacggcag
     5641 ccgattgcga aataaacgcc agcttgccgc gtttaatcgg cacaggcgaa aagctggcat
     5701 tcagaccttg ccagggagcc agtaaaccca gactgtttgg tccaagcagg cgcatgttat
     5761 ggcgcagggc gcaggcgcgg agatcttcgt gttgcgatgc cggggcggaa agaataatgc
     5821 aggttttaca gcctttctcg ccgagctctt ccagaagagc aagattacgg ctggcattgg
     5881 tacataaaac cgcaaggtcg ggtgtaaagg gcaagctggc aatatccggc caggccaaca
     5941 cacccaacac cgctttccag gctggcgtca ccgggagtac cggtccgtta aagcctcccg
     6001 ccagcaggtt acgcatcatc aggtaacctg cgcgattggg tttcatcgac gcgccaatta
     6061 ccgctatcga ttttggtcgc agtagtgctt ccagtcctcg ctgactcata ccggtctccc
     6121 gcagaagtga ccgaatgatt ttaaacgctt tctaactgtt ctgctgtgat gctacccaga
     6181 tgttgcgttt ttcctgccag atagcgtgtt ttaaagcggg taaaatgctc gcctaaccct
     6241 gccgccgccc cggtatcgcc ggccatatct aacagtgcga tggctacctc ggcagtacaa
     6301 tattggcctt cagcctgggc ttcacgcagg cgataggcag aaagccggga aagatcgacg
     6361 gaaatgacgg gaagattatc cagatacgga cttttacgaa acatcttgcg agcttccggc
     6421 caggtaccat cgagcatgat aaacagcggt ggcttaccgg caggtggtgt gaagatcact
     6481 tcccgttgct catcagcata cgaagcggga aagaccacca ttggctgata gtccgggttt
     6541 tgcaccaact ccagcaaatc ctgcgagggt tcggtacgcg accattgaaa cgcaacggta
     6601 tcaggcaaaa tatcagcaat gagacgcccg gtattactgg gcttcattgg ctcggtgtcg
     6661 aacatcagca aacagaagcg actttttgct tgtgctgggg taattgtcga acagagacat
     6721 aatttctctg gcaaaagaca gcgttggcag cgacgaacgc gattaccgcg ggcaagaaaa
     6781 ggacgtgttg cgcgcgcaat acgctcggcg cgtaactgga gaacagcgtt ttcggtcata
     6841 agagagcgtc gaaaaaacgc cattgtcgca gaggagaaaa cggggcacaa gatgcgcccc
     6901 ggtaagatta aagagattcg ttcagccagc tatcgaacgg cgctttcggt actgcgccat
     6961 taagcatgtc gacaacctga ccgtttttga aaatcatgat cgtcggtata ctacgaattc
     7021 caaagcgact gctcaattca cgttcagctt cggtattcac tttcacaaag cgcactttac
     7081 cgctacgctc ttgcgcgaca tcttcaaaaa ttggtgcgaa attacggcag gggccgcacc
     7141 acggtgccca gaagtcgatc accacaggta gatcatcctt cagcaatttg tcgagtgttt
     7201 caccggtcgc attaatcacc tctccgtcaa acaagtcgtg accgcagcgt ccgcattttg
     7261 ccgcatcttc gatccgatcg tcgggaatgc gattgatggc ctgacaatgg gtacaaacgg
     7321 tattcataac taacctcggg atgagtaagg agacttatcg gcaacgacgc cggtatgttt
     7381 ctaatatgtt acatattatc ggggacattg ttccagacaa caatctgttt tattcaatag
     7441 gtatgatagt cgcaggcttt ggtacgaaat catggcgaac cgcgcggact tcgggtaatc
     7501 tgcgcgcttc gcgcagcgct ggtggagaaa agcatgaacg atgaaatgaa aggtaaaagc
     7561 ggcaaggtca aagtgatgta tgtccgcagt gatgatgatt ctgataaacg tacccacaac
     7621 ccgcgtaccg ggaaaggggg cgggcgtcca ggaaaatctc gtgctgacgg tggccgtcgc
     7681 cccgcccgcg atgacaaaca gagtcagccc cgtgaccgca agtgggaaga ttcgccgtgg
     7741 cgcacggttt cccgcgcgcc gggtgatgag acgccggaaa aggccgatca cggtggcatc
     7801 agtggtaaaa gttttattga tccggaagtg ttgcgtcgtc agcgtgcgga agaaacccgc
     7861 gtctacggcg aaaatgcatg tcaggcactt ttccagagcc gtccggaagc gattgttcgc
     7921 gcctggttta tccagagtgt aacgccgcgt tttaaagaag ctttgcgctg gatggcagca
     7981 aaccgcaaag cgtaccatgt ggtggatgaa gcggaattga caaaagcgtc aggcacggaa
     8041 catcacggcg gcgtttgctt cttgatcaaa aagcgtaacg gtacaaccgt gcagcagtgg
     8101 gtaagccagg caggcgcgca ggattgcgtt ctggcactgg aaaacgaatc taacccgcat
     8161 aacctgggtg gcatgatgcg cagctgcgcg cacttcggcg tgaaaggtgt cgtggtgcag
     8221 gatgcggcac tgctggagtc gggggcggct atccgtaccg cagaaggcgg cgcagagcac
     8281 gttcagccga ttactggcga caacattgtt aacgtgctgg atgatttccg tcaggcaggt
     8341 tacaccgtag tgaccacttc cagcgagcag ggtaaaccgc tgttcaaaac tagtctgcca
     8401 gcgaaaatgg tactggtgct gggtcaggaa tatgaagggt taccggatgc cgcacgcgat
     8461 ccgaacgatc tgcgcgtgaa gattgacggt acgggcaacg ttgccgggct gaatatctct
     8521 gtcgcaaccg gcgttttgct tggtgaatgg tggcgtcaga ataaagcctg ataaatcagc
     8581 cgggtggcaa ctctgccatc cggcatttcc ccgcaaattt actcactctc tgccggtaat
     8641 actggcatcc agtcaatcgg cgtctcgcca cgttgttcca gccactgatt tgccagcaca
     8701 aaatggttgc agccaaagaa tccacgatgc gccgaaagcg gcgacggatg cggtgctttc
     8761 agtacatgat ggcgttgctt atctataatc gcccctttct tttgcgcatg cgatccccac
     8821 aacaaaaaca ccacgccttc gcgatgctgg ttaatcaggc tgatcacttt atcggtgaag
     8881 gtttcccagc cgaggctggc gtgggaatgc gcctgacctg cgcgtaccgt caacacagta
     8941 ttgagtagca gaacgccctg acgcgcccag ctttcaagat aaccatgatt agggcgggtg
     9001 aagcccggaa tagtattttc cagctcttta tacatattca ataatgacgg aggaatggca
     9061 atgccgggac gaacggaaaa tgccagacca tgcgcctgtc ccggtccgtg ataaggatcc
     9121 tggccgagaa tcaccacttt aacgtcaccc aactctgtaa agcggaacgc gttaaagaca
     9181 tctttttgtg gtgggtagat agtgacgccg gactgccgct cgctggcgac ggtctgaagg
     9241 gtattaagaa aatagggttg ctgcttctct tcagccagca cgtcatgcca ggttaattcg
     9301 ttagccatct cgctctcctg cgaatcttca atccgcctag cttaactgct tctttctaca
     9361 gaacaaaatc atgctcattt tttagactta aacgagtgca aaaaaatgta aattggtaaa
     9421 atttcacacc cgcataagtt gatgtaaaac aataaaatcc atttgcgacc atacttgatg
     9481 tgtggttttt attgatttaa atcaaagatt caagggtgtt tgaggagtat atatacactc
     9541 aagcaacaat ggttttacca attggccgcg acaggctgaa caaatcaaat aattttgccg
     9601 gggaggcatc acatgattac aggtatccag attactaaag ccgctaacga cgatctgctg
     9661 aactctttct ggctgctgga cagcgaaaaa ggcgaagcgc gttgcatcgt tgcaaaagca
     9721 ggttatgcag aagatgaagt ggttgcagta agcaaactgg gtgacattga ataccgtgaa
     9781 gttccagtag aagtgaaacc agaagttcgc gttgaaggtg gtcaacacct gaacgttaac
     9841 gttctgcgtc gcgaaactct ggaagatgca gttaagcatc cggaaaaata tccgcagctg
     9901 accatccgtg tatccggtta tgcagttcgc tttaactctc tgactccgga acagcagcgc
     9961 gacgttatcg ctcgtacctt tactgaaagc ctgtaaggct taagtagcaa gttactaagc
    10021 ggaagagggc gacctcttcc gctttttttc gttaatagaa aatgtgtacc gcgcaataga
    10081 ccagcaacag ggcaagcacg atatttaact ggcgaccata ctggcgaaac aatcgctgaa
    10141 acagatgccc cgccagcgcc cagcacacat tgccaaacgt cccaatcatc gccagcaaaa
    10201 cgctgacgcc aactacccag cttaacgcct gtgtttgcgg cagaacaaac gtcgacagtg
    10261 ccgtaacacc gtacaaaatg attttgacgt tcacaaactg caaagcaaag ctggcccaaa
    10321 agctgattgg ttttgcctga agtccgtctt cctttgttgg gctggtggcg attttccacg
    10381 ccagccagac aatatatgcc gcccccgccc aactcaaaag gtgtaccgct gccgggtcaa
    10441 tcactgccag tgaaaatgaa atgcccgcac acagtaacat cacaatcaaa aatcccagac
    10501 tcatccctgc cagcacgcgg gtactttgac gaaatccatg cgacgtagca gagctaaggg
    10561 cgagaatatt gttcggtcct ggcgtcatag cggtaatcag ggtgtaagtc caaaaagcac
    10621 ttaaaagggt cggtgtcact tgttatctcc tctgttttgg tagacagtac ccgacacgga
    10681 acatttaaaa aaatgaatgt ttttatattc tagattcgat attttcgata ggtttggggt
    10741 tatggatctg cgccgtttta ttacgcttaa aaccgtggtg gaagagggtt cctttttgcg
    10801 agcttcgcaa aaattgtgct gtacacaatc gacggtgact tttcatattc agcagcttga
    10861 gcaggagttt tcagtccagt tatttgagaa aattggccga cggatgtgcc ttacccgcga
    10921 aggaaaaaag ttgctgccgc acatttatga acttacccga gtgatggata cgcttcgtga
    10981 ggctgccaaa aaggagtcag atccggacgg ggaactacgc gttgtttcgg gcgaaacgtt
    11041 gctctcttac cgaatgccgc aggtgttgca gcgttttcgg caacgcgccc caaaagtgcg
    11101 tttatcgttg cagtcgctga actgttacgt gatccgtgat gcgctactga atgatgaggc
    11161 cgatgttggc gtcttttatc gtgtagggaa tgatgatgct ctgaatcgac gagagttggg
    11221 tgaacaatca ctggtgctgg tggcttcacc gcaaattgca gatgtcgatt ttactgagcc
    11281 gggaagacat aacgcctgta gctttattat caacgaaccg caatgtgtct tccggcagat
    11341 atttgagagc acgctgcgtc agcggcggat cacggtggaa aacaccattg agcttataag
    11401 tatcgaaagc atcaagcgtt gtgtcgcggc gaatatcggg gtcagctacc taccgcgctt
    11461 tgcggtggca aaagagttgg agtgcggaga attaattgaa ttgccttttg gcgaacagtc
    11521 gcagaccatt acggccatgt gcgcacatca tgctggaaaa gcggttagcc cggcgatgca
    11581 cacttttatt cagtgtgttg aagagagttt tgtggctgga taaaaataat gtcgggatta
    11641 aacccggcat ttaacttgtc gacaaagtgc gctttattca tgccggatgc ggcgtgaacg
    11701 ccttatccgg cctacaagat cgtgcaaatt caatatattg catgagccac gtaggcctga
    11761 taagcgtagc gcatcaggca gttttgcgtt tgccagcact tttaatacca ggcttaaacc
    11821 tggcattgag attactcttc tgtcgtttgc ggtggcacgc ccgttccgct tggtttacgg
    11881 cgcttaccaa tatttttggt gtcgcgatgg cgttttttca cccgcggctt ctctttctct
    11941 ttagcttttt tcttctcagc acgtttagcc agtactttct tcgatggctt gccggtctgc
    12001 ttttcgcttg gcgcacgcgt tttcgggcgt aactcatcaa taacgcgagc tttaattggc
    12061 tcttcaatat agcggcctac tttacccagc agcagatggt catgggcttc caccagcgaa
    12121 attgcggtgc ctttacgacc ggcgcgcgcg gtacgtccga tacggtgcaa ataagtatcg
    12181 ccactgcgcg gcatatcgaa gttaaagacg tggctgacgt caggaatgtc gataccgcgc
    12241 gcggcaacat cggttgcgac cagtacgttt acgcgacctt cggtcaaacg cttgatcgct
    12301 tcgttacgct tgccctgtac catctcacct tcgagatagc agttgttgat gcccgcttcg
    12361 cgcagccagt ttgccagctc atgcacacgc tcacgcttac gcacaaacac aattgagcgg
    12421 gtcgcttccg gctgttttaa cagatgcacc agcaacgcgg ttttatgctc aagatcatcg
    12481 gcgcggtaat accactgatg aatttttttg cgctcacggg tggagggatt ggcagaaact
    12541 tccaccggat cttccagcag acgctcggca aagtcctgaa tcgcatcgcc ttccagcgtt
    12601 gccgaaaaga gcagggtctg tttacgccag cgcgtttcgc cagcaatatg ttcgatatcc
    12661 tgagcgaagc ccatatccag catacggtct gcttcgtcga ggatcagcgt ttcaaccgcg
    12721 cggcaatcga agttctcttc ttttatgtat tgcagcagac gtccggtcgt ggcgaccacg
    12781 atgtcctgat tttcgctgaa cacttccgcg tggttcatat aggctacgcc gccggtgatg
    12841 gtggcgatat ccagatgcgt atgtttcgcc agttcgcggg catgatcggc cacctgcatc
    12901 gccagctcgc gagttggggt gaggatcaaa atacgcggcg gaccggattt cttacgcggg
    12961 aaatcgagca ggtgctgcaa cgctggcagc agatacgccg ccgttttacc ggtgcctgtc
    13021 ggcgcagaac cgagtacatc acggccatcg agcgcaggcg gaatggcggc agcctgaatg
    13081 gcggtcgggc gagtgaaacc tttatcctgg agggcttcca gcaggctttc gtcgagttca
    13141 agttcggaaa aagtcgttac agtcatgttc tacctctgtg tggggcgctg attatagacg
    13201 ttacggctgc aatcttcatc tgtttgtatg gatatcgctt ctcgggtatt gttctcaccc
    13261 ggtgctatcg ccgtttttcc tgcaaggttt tattttcatg tcacagtcta catccgtgct
    13321 tcgtcgtaat ggatttactt ttaaacagtt ttttgttgct cacgatcgct gtgcgatgaa
    13381 agtgggaacg gatggtattt tattgggcgc atgggcaccg gtggctgggg taaaacgttg
    13441 ccttgatatc ggcgcgggta gcgggttgct ggcattaatg ctggcgcagc gaaccgatga
    13501 cagcgtgatg attgatgcag ttgaactgga aagtgaagct gccgcgcagg cgcaggaaaa
    13561 tatcaaccag tccccgtggg cagagcggat taacgtccat acggcggata ttcagcagtg
    13621 gatcacacag cagacagtac gcttcgattt aatcatcagt aacccacctt actatcagca
    13681 gggagtagag tgctcgacac ctcaacggga acaggctcgc tataccacta cgcttgatca
    13741 cccatcgttg ctgacctgtg cggcggagtg cattaccgaa gagggatttt tctgcgtagt
    13801 gctgccagag cagattggta atggttttac ggagctggca ttaagcatgg gctggcattt
    13861 acgtttgcgg acggatgtgg cggaaaacga agcgcgactg ccgcatcggg tgctgctggc
    13921 attctccccg caggcgggag aatgctttag cgatcgctta gtcattcgtg ggccagacca
    13981 gaactattcc gaagcgtata cggcgctgac ccaggctttt tatctgttta tgtaatgatt
    14041 gccgggggaa aggatcgacg gaccggaatg ggtgagcagt tccggataat ccagcgtgaa
    14101 atgcaacccc cgactctctt tacgcatcat tgcacagcga acaatcaact cggcaacctg
    14161 taccagatta cgcagctcca gcaaattatt tgagacgcgg aaatgggcgt aatattcgtc
    14221 tatttcttgt tggagcatgg ttatccgccg cagggcgcgt tccaggcgct tcgttgtgcg
    14281 cacaatgcca acgtaatccc acataaacag acgtagctcg tgccagttat gctgaattac
    14341 tacccgttcg tcagggttct caacgcggct ttcatcccac ggcggtaacg tactgatgtc
    14401 gtgggcataa ggcatacgtc tggtgatatc ttccgccgcc gaccagccat agaccagaca
    14461 ctccagcaat gaattcgagg ccatgcggtt agcgccgtgt aagccggtat aactcacctc
    14521 gccaatggca tacaagccct cgacgtccgt acgcccatga tcatcaacca ttacaccacc
    14581 gcaggtataa tgtgcagcag gcacaatcgg taccggttct tgtgtgagat caatccccag
    14641 cccgagcagc ttttcataaa tcatcgggaa atgctggcga ataaaatcgg cgggcttatg
    14701 gctgatatca aggaacatac aatctgcgcc gaggcgtttc atttcatggt caatggcgcg
    14761 ggcgacaata tcgcgcgggg ccagttcgcc gcgctcatca aaatcgggca taaaacgcgt
    14821 accatccggg cgcttgagat aagcgccttc gccgcgcagt gcttctgtta acaggaaatt
    14881 gcgtgcctgt gggtgatata gcgcggtagg gtggaactga ttaaattcga gattggcaac
    14941 ccggcagcct gcgcgccacg ccatagcaat gccatcgcca gaagaaatat ccggattggt
    15001 ggtgtactga taaaccttcg acgcaccgcc ggttgccagc accaccgctt ttgcgtggca
    15061 ggtttccacc gtttctttat tacggttcca tacccacgcg ccaacaaccc gtcgcgtgcc
    15121 cggcaggcca attttgtcag aaacaatcag atcaaccgcg ttgctgcgct ccagcacgcg
    15181 aatattcgga tggttcagcg ccttgctcac cagcgtggtt tctacttctc taccggtggc
    15241 gtcggcggca tgaagaatac gacggtgact atgtccacct tcacgggtca gatggtaact
    15301 ttcttcgcca ttcggttgaa tgtgggtatc aaacaacacc ccctggtcga ttagccattg
    15361 cacacaggat cgtgcattgc tggcgacaaa ttcaactgca tggcgatcgc aaataccagc
    15421 cccggcaatc aatgtgtctt ccacatgcga gtcaatgctg tcagtttcat caaacacggc
    15481 ggcaataccg ccctgggcat aaaatgttga accttccgtt accgggcctt tacttagaac
    15541 gatgacctga tgctggtcag ccaggcgtag cgccagtgaa agtccggctg cgccgctacc
    15601 gataatcaac acgtcacatg aatgttcagg gagagtattc attttctttg tttaatttac
    15661 taaacatggt ttggtcagca tagcatcatg ttgtgcggat aaacacctgc tattttaata
    15721 tttgttacag ttgctaaaca cgctgacgca gggcggcgag aaaaagagaa gttactggct
    15781 ggtggaggat taggtggtga aataaaaagg ccgttgggtt actcttcagg cagttaaatg
    15841 ggcatttcta cacagataat gcgatgttca gattctgtag acttataatg atagataatg
    15901 atccgtctac agcatgacaa acaaaaacag atgcgttacg gaactttaca aaaacgagac
    15961 actctaaccc tttgcttgct caaattgcag ctaatggagt ggcgtttcga tagcgcgtgg
    16021 aaatttggtt tggggagact ttacctcgga tgagcgagca gttaacggac caggtcctgg
    16081 ttgaacgggt ccagaaggga gatcagaaag cctttaactt actggtagtg cgctatcagc
    16141 ataaagtggc gagtctggtt tcccgctatg tgccgtcggg tgatgttccc gatgtggtac
    16201 aagaagcttt tattaaagcc tatcgtgcgc tggattcgtt ccggggagat agcgcttttt
    16261 atacatggct gtatcggatt gctgtaaata cagcgaaaaa ttacctggtt gctcaggggc
    16321 gtcgtccacc ttccagtgat gtggatgcca ttgaagctga aaacttcgaa agtggcggcg
    16381 cgttgaaaga aatttcgaac cctgagaact taatgttgtc agaagaactg agacagatag
    16441 ttttccgaac tattgagtcc ctcccggaag atttacgcat ggcaataacc ttgcgggagc
    16501 tggatggcct gagctatgaa gagatagccg ctatcatgga ttgtccggta ggtacggtgc
    16561 gttcacgtat cttccgagcg agggaagcta ttgataacaa agttcaaccg cttatcaggc
    16621 gttgacgata gcgggatact ggataagggt attaggcatg cagaaagaac aactttccgc
    16681 tttaatggat ggcgaaacgc tggatagtga gctgcttaac gaactggctc ataacccaga
    16741 aatgcagaaa acctgggaaa gctatcactt aatccgtgac tcaatgcggg gtgatactcc
    16801 cgaggtgctc catttcgata tctcttcacg cgtgatggcc gccattgaag aagagccagt
    16861 acgtcaaccg gcgacattga tcccggaagc ccagcctgcg ccgcatcaat ggcagaaaat
    16921 gccattctgg cagaaagtac gtccgtgggc ggcacagctt acccaaatgg gcgtagccgc
    16981 atgcgtatcg cttgcagtta tcgttggcgt ccagcactat aatggacaat ctgaaacgtc
    17041 ccagcagccc gaaacgccgg tatttaatac actgccgatg atgggtaaag ccagcccggt
    17101 aagcctggga gtaccttctg aagcgaccgc aaacaatggt caacagcagc aggtacagga
    17161 gcagcgtcgt cgcattaatg caatgttgca ggattacgaa ctgcaacgcc gactccactc
    17221 tgaacagctt cagtttgagc aggcgcaaac ccagcaagcc gctgtacagg tgccaggaat
    17281 tcaaacttta ggaacgcaat cgcagtaatg aagcaacttt ggtttgccat gtcattagtg
    17341 acaggtagcc tgttattctc tgctaacgcc tcggccactc ccgcgtccgg ggcgttatta
    17401 cagcagatga acctggccag tcagtcactg aattacgagc tgtcattcat cagcatcaat
    17461 aaacagggtg ttgagtctct gcgttatcga catgcacgcc tcgataaccg tcctcttgca
    17521 caattgttgc aaatggatgg cccgcgccgg gaagtggtac agcgcggcaa tgaaatcagc
    17581 tattttgaac cgggacttga accgttcacg cttaatggcg attacattgt tgattctctg
    17641 ccatcgctta tctataccga tttcaaacgc ctttctcctt actacgactt tatctccgtc
    17701 gggcgcacgc gtattgctga tcgtctttgc gaagtcattc gcgtggttgc ccgagatggt
    17761 acacgctaca gctacatcgt gtggatggac accgaatcga aattaccgat gcgggttgat
    17821 ctccttgatc gcgatggtga aacgctggaa caatttcgcg tgattgcttt taacgtcaat
    17881 caggatatca gcagcagtat gcagacgctg gcgaaggcaa atttgccgcc gttgctttct
    17941 gttcctgtag gtgaaaaagc taaattcagc tggacgccaa cctggttgcc acagggtttt
    18001 agcgaagttt ccagtagtcg acgtccgcta ccgacgatgg acaacatgcc tatcgaatca
    18061 cgtctctatt ccgacggatt attcagcttc tcggtaaacg ttaaccgcgc tacgccatcg
    18121 agcaccgatc agatgttgcg caccggacgc agaaccgtca gtacaagcgt acgtgataac
    18181 gccgaaatca ccattgtcgg tgaactgccg ccgcaaacgg cgaaacgcat tgccgagaat
    18241 attaagttcg gggcagcgca atgatcaaag agtgggctac cgtcgtctcc tggcaaaacg
    18301 ggcaggcgct ggtcagttgt gatgttaaag cttcatgcag cagctgcgct tcacgcgccg
    18361 gttgcggtag ccgcgtgtta aataaacttg gcccgcaaac cacgcatacc attgtcgtac
    18421 cctgtgatga gccgttagtg ccggggcaaa aagtggaatt ggggatcgcc gaaggcagcc
    18481 tgcttagctc cgcattactg gtttatatgt cgccgctggt gggattattc cttatcgctt
    18541 cgctatttca gctactcttt gcttctgacg tcgcagcatt atgtggtgcg atcctcggtg
    18601 gtattggcgg gttcctgatt gcgcgcggct actcgcgtaa gtttgctgcc cgggcagaat
    18661 ggcaaccgat catcttaagc gtggcattgc cgcctggcct tgtgcgattt gaaacatctt
    18721 cggaagacgc gagccagtga tttcactggc tttgttgcat tttgcataac aaatgcgagg
    18781 acgtttccag ataccacaat ccatacggta tgaacatttc ctcgcctcaa tgttgtagtg
    18841 tagaatgcgg cgtttctatt aatacagacg ttaagctcag aacagcgact tctaaaagcc
    18901 tggttaaccg ggcattaagg cacaataatc atactttatg aagaatatac gtaacttttc
    18961 gatcatagct cacattgacc acggtaaatc gacgctgtct gaccgtatta tccagatctg
    19021 cggtggcctg tctgaccgtg aaatggaggc gcaggttctc gattccatgg atcttgagcg
    19081 tgagcgtggc attaccatca aagcgcaaag cgtgacgctg gactacaaag cgtctgacgg
    19141 cgaaacctat cagcttaact ttatcgacac cccgggccac gtagacttct cctatgaagt
    19201 ttcccgttcg ctggctgcct gtgaaggtgc attgctggtg gtcgacgccg ggcagggcgt
    19261 agaagcgcaa accctggcaa actgctacac cgccatggaa atggatctcg aagttgtgcc
    19321 ggtactgaac aagattgacc tgccggcagc cgatcctgaa cgcgtggcgg aagaaattga
    19381 agatatcgtc ggcatcgacg ccaccgacgc ggtgcgctgt tcagcgaaaa ccggcgttgg
    19441 tgtgcaggac gttctcgaac gtctggttcg cgacattccg ccgccggaag gcgatccgga
    19501 aggcccgttg caggcactaa ttatcgactc atggttcgac aactacctgg gcgttgtttc
    19561 acttatccgt attaaaaacg gcaccctgcg taagggcgac aaagtgaaag tcatgagtac
    19621 cgggcagacc tataacgccg accgtctggg catcttcacg ccgaaacagg ttgaccgcac
    19681 tgaactgaaa tgtggcgaag taggctggct cgtatgtgcg attaaagata tccacggcgc
    19741 tccagtcggc gataccttaa cgctggcgcg taatccggca gaaaaggcgc tgcctggctt
    19801 taagaaagtc aaaccgcagg tatacgccgg tctgttcccg gtaagttccg acgactatga
    19861 agccttccgt gacgcgctgg gtaaactcag cctgaacgat gcctcactgt tctatgagcc
    19921 ggaaagctcc agcgcgctgg gctttggttt ccgctgcggc ttcctcggcc tgctgcacat
    19981 ggagatcatc caggaacgtc tggaacgtga atacgatctg gatctgatca ccactgcgcc
    20041 gaccgtagtg tatgaagttg aaaccacgtc aagagaagtt atctacgtcg acagcccatc
    20101 caagctgcct gcggtaaata acatctacga actgcgcgag ccgattgcag agtgtcacat
    20161 gctgctgccg caggcatatc tcggcaacgt tattacgttg tgcgtagaaa aacgcggcgt
    20221 gcagaccaat atggtttacc acggtaatca ggtggcgctg acgtacgaga tcccgatggc
    20281 ggaagtggtg ctcgacttct tcgatcgcct gaaatctacc tcgcgtggtt atgcgtctct
    20341 ggattacaac ttcaagcgct tccaggcgtc cgacatggta cgtgtagacg tattaatcaa
    20401 cggtgaacgt gttgatgcgc tggcgttgat cacccaccgt gataattcgc aaaaccgcgg
    20461 tcgcgagttg gtggagaaga tgaaagatct gatcccacgc cagcagtttg atatcgccat
    20521 tcaggcagcg attggtacgc acatcattgc gcgatccacc gtgaaacagc tgcgtaaaaa
    20581 cgtactggct aaatgttatg gcggcgatat cagccgtaag aaaaagctgt tgcagaagca
    20641 gaaagaaggt aagaaacgca tgaagcagat cggtaacgtc gagctgccgc aggaagcgtt
    20701 cctcgccatt ctgcacgtcg gcaaagacaa caaataaccc ttaggagttg gcatggcgaa
    20761 tatgtttgcc ctgattctgg tgattgccac actggtgacg ggcattttat ggtgcgtgga
    20821 taaattcttt ttcgcaccta aacggcggga acgtcaggca gcggcgcagg cggctgccgg
    20881 ggactcactg gataaagcaa cgttgaaaaa ggttgcgccg aagcctggct ggctggaaac
    20941 cggtgcttct gtttttccgg tactggctat cgtattgatt gtgcgttcgt ttatttatga
    21001 accgttccag atcccgtcag gttcgatgat gccgactctg ttaattggtg attttattct
    21061 ggtagagaag tttgcttatg gcattaaaga tcctatctac cagaaaacgc tgatcgaaac
    21121 cggtcatccg aaacgcggcg atatcgtggt ctttaaatat ccggaagatc caaagcttga
    21181 ttacatcaag cgcgcggtgg gtttaccggg cgataaagtc acttacgatc cggtctcaaa
    21241 agagctgacg attcaaccgg gatgcagttc cggccaggcg tgtgaaaacg cgctgccggt
    21301 cacctactca aacgtggaac cgagcgattt cgttcagacc ttctcacgcc gtaatggtgg
    21361 ggaagcgacc agcggattct ttgaagtgcc gaaaaacgaa accaaagaaa atggaattcg
    21421 tctttccgag cgtaaagaga cactgggtga tgtgacgcac cgcattctga cagtgccgat
    21481 tgcgcaggat caggtgggga tgtattacca gcagccaggg caacaactgg caacctggat
    21541 tgttcctccg ggacaatact tcatgatggg cgacaaccgc gacaacagcg cggacagccg
    21601 ttactggggc tttgtgccgg aagcgaatct ggtcggtcgg gcaacggcta tctggatgag
    21661 cttcgataag caagaaggcg aatggccgac tggtctgcgc ttaagtcgca ttggcggcat
    21721 ccattaatag ccatcttcgt tcacgttgtc gccgttatgg cgacaacgtg aattatttat
    21781 gagataaatc tcccgtggct aacgacatcc cccgtcgttg tgtatagaat attcccccga
    21841 agtttaaggt tggcacctcc aggttgccac ggcacacgaa acagcgttgg tccccatata
    21901 ccggtaaact gaaactgcag cgaagcagtt agcagaacca tgtatatcag gtctgtttcg
    21961 tgtgctgaat tgttgacgca tttatttatt ggtatcgcat gaaccccatc gtaattaatc
    22021 ggcttcaacg gaagctgggc tacactttta atcatcagga actgttgcag caggcattaa
    22081 ctcatcgtag tgccagcagt aaacataacg agcgtttaga atttttaggc gactctattc
    22141 tgagctacgt tatcgccaat gcgctttatc accgtttccc tcgtgtggat gaaggcgata
    22201 tgagccggat gcgcgccacg ctggtccgtg gcaatacgct ggcggaactg gcgcgcgaat
    22261 ttgagttagg cgagtgctta cgtttagggc caggtgaact taaaagcggt ggatttcgtc
    22321 gtgagtcaat tctcgccgac accgtcgaag cattaattgg tggcgtattc ctcgacagtg
    22381 atattcaaac cgtcgagaaa ttaatcctca actggtatca aactcgtttg gacgaaatta
    22441 gcccaggcga taaacaaaaa gatccgaaaa cgcgcttgca agaatatttg cagggtcgcc
    22501 atctgccgct gccgacttat ctggtagtcc aggtacgtgg cgaagcgcac gatcaggaat
    22561 ttactatcca ctgccaggtc agcggcctga gtgaaccggt ggttggcaca ggttcaagcc
    22621 gtcgtaaggc tgagcaggct gccgccgaac aggcgttgaa aaaactggag ctggaatgag
    22681 catcgataaa agttactgcg gatttattgc catcgtcgga cgtccgaacg ttggcaaatc
    22741 cacattgttg aacaaactgc tggggcagaa aatctccatc acttcccgca aggcgcagac
    22801 aactcgtcac cgcattgtgg ggatccatac tgaaggcgcg tatcaggcga tctacgtcga
    22861 tacaccgggc ctgcatatgg aagaaaaacg cgccattaac cgcctgatga acaaagcggc
    22921 gagcagctct attggcgatg ttgagctggt gatttttgtc gttgaaggca cccgctggac
    22981 gccggacgac gaaatggtgc tcaacaaact gcgcgaaggc aaagcgccgg taatcctcgc
    23041 ggtgaacaaa gtggacaacg tgcaggagaa agccgatctg ctgccgcacc tgcagttcct
    23101 ggcaagccag atgaacttcc tcgatatcgt gccaatctct gccgaaaccg ggctgaatgt
    23161 tgacactatt gcggcaatcg tgcgtaagca tctacctgaa gcgactcatc acttcccgga
    23221 agattacatc accgatcgct cacagcgttt tatggcgtct gaaatcatcc gcgaaaaact
    23281 gatgcgtttc ctcggcgctg aactgccgta ctccgtgacc gtggagatcg aacgtttcgt
    23341 ctctaacgaa cgcggtggtt atgacatcaa cggtttgatt ctcgttgagc gtgaagggca
    23401 gaagaagatg gtcattggca acaaaggggc caagatcaaa accatcggga ttgaagcgcg
    23461 taaagacatg caggaaatgt tcgaagcgcc tgttcacctt gaactgtggg taaaagtgaa
    23521 atccggttgg gccgacgacg aacgcgcact gcgcagtctc ggttacgttg acgatcttta
    23581 agagtaactc cgatggaagg ctggcagcgc gcatttgtcc tgcatagtcg cccgtggagc
    23641 gaaaccagcc tgatgctgga cgtcttcacg gaggaatcgg ggcgcgtgcg tctggttgcc
    23701 aaaggcgcac gctctaaacg ctctaccctg aaaggtgcat tacagccttt cacccctctc
    23761 ttgctacgtt ttggcgggcg tggcgaagtc aaaacgctgc gcagtgctga agccgtctcg
    23821 ctggcgctgc cattaagcgg tatcacgctt tacagcggtc tgtacatcaa cgaacttctc
    23881 tcccgcgtac tggaatacga gacgcgcttc tctgaacttt ttttcgatta cttgcactgc
    23941 attcagtctc ttgcaggggt cactggtacg ccagaacccg cgctgcgccg ctttgaactg
    24001 gcactgctcg ggcatctggg ttatggcgtc aattttaccc attgtgcggg tagcggcgag
    24061 ccggtagatg acaccatgac gtatcgttat cgcgaagaaa aagggtttat cgcaagcgtc
    24121 gttatcgaca ataaaacgtt caccggaagg cagttaaaag cgttaaacgc acgggaattt
    24181 cctgacgcag acacactgcg cgccgcgaaa cgctttaccc gcatggcgct taagccgtat
    24241 cttggcggta aacctttaaa gagcagggaa ctgttccggc agtttatgcc taagcgaacg
    24301 gtgaaaacac attatgaatg atgaggattg tcatggctga attactgtta ggcgtcaaca
    24361 ttgaccatat cgctacgctg cgcaacgcgc gcggtaccgc ttacccggat ccggtgcagg
    24421 ccgcgtttat tgccgagcag gcgggagcgg acggcattac cgtgcattta cgtgaagatc
    24481 gccgtcacat tactgaccgc gacgtgcgca tcctgcgtca gacgctggat acccgcatga
    24541 atctggagat ggcggtgacc gaagagatgc tggcgatcgc cgttgagacg aagccacatt
    24601 tttgctgcct ggtaccggaa aagcgtcagg aagtaacaac cgaaggcggc ctggatgtcg
    24661 cagggcagcg tgacaaaatg cgcgatgcct gcaaacgtct ggcagatgcc gggattcagg
    24721 tttctctgtt tattgacgcc gatgaagagc agatcaaagc tgcggcagag gttggcgcac
    24781 cgtttatcga gatccacacc ggttgctatg ctgatgccaa aactgacgcc gaacaggcgc
    24841 aagagctggc gcgtatcgcc aaagccgcga cctttgccgc aagcctcggt ctgaaagtta
    24901 acgccggaca cggtctgacc tatcacaacg tgaaagccat tgccgccatc cctgagatgc
    24961 atgaactgaa tatcggtcat gccattattg gtcgtgcagt gatgaccgga ctgaaagatg
    25021 cggtggcaga aatgaagcgt ctgatgctgg aagcgcgtgg ctaatggcaa tattaggttt
    25081 aggcacggat attgtggaga tcgctcgcat cgaagcggtg atcgcccgat ccggtgatcg
    25141 cctggcacgc cgcgtattaa gcgataacga atgggctatc tggaaaacgc accaccagcc
    25201 ggtgcgtttt ctggcgaagc gttttgctgt gaaagaagcc gcagcaaaag cgtttggcac
    25261 cgggatccgc aatggtctgg cgtttaatca atttgaagta ttcaatgatg agctcggcaa
    25321 accacggcta cggctatggg gcgaggcatt aaaactggcg gaaaagctgg gcgttgcaaa
    25381 tatgcatgta acgctggcag atgagcggca ctatgcttgt gccacggtaa ttattgaaag
    25441 ttaaaaataa taccgttctc tttaaaaagt aaaacccccg aactggtaag gaacgggggt
    25501 tttacttttt aactttaatt ttgtgcagca tgcaccctca acaacagcga ttatggatca
    25561 gtgtacttat cttttacaag caacttgcaa tctttagcat aaaaactcga gcctttacga
    25621 agaaagcaat attgatggaa agattaacgt gaccgccaat tcgtaagtac attaaaattg
    25681 gcttcgttat tgaagatttt gctgtgcttt acaccatgcc acagaattcc cccattgaaa
    25741 cgagtggtgt cgtcaaagct ctggtgtgga gtgcagcatg caccctcaat aactcgcacg
    25801 ttcagttttg gggagatgta agggctaatc tgaatggctg cattccttgt ttaaggaaaa
    25861 acgaatgact gattgccgat acctgattaa acgggtcatc aaaatcatca ttgctgtttt
    25921 acagctgatc cttctgttct tataacacaa ggaaacgtac ttaaggtgcg tccggtgaac
    25981 cagtcggacg cacctttaat aact
//
LOCUS       DAPHKZ010000060        25308 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.060, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000060 DAPHKZ010000000
VERSION     DAPHKZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25308
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.060"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            209..628
                     /locus_tag="RH288_002602"
     CDS             209..628
                     /locus_tag="RH288_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HDV4031648.1"
                     /translation="MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLL
                     IQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLR
                     PTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR"
     gene            628..1896
                     /gene="umuC"
                     /locus_tag="RH288_002603"
     CDS             628..1896
                     /gene="umuC"
                     /locus_tag="RH288_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V catalytic protein"
                     /protein_id="HDV4031649.1"
                     /translation="MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEA
                     KALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDE
                     AFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     GGVVDLSNLERQRKLMSALPVDDVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHF
                     NVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYPSMRQAICSYAARAAE
                     KLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSRDIINAATRSLDAIW
                     QAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMTVMDTLNAKEGRGTLYFA
                     GQGIQQQWQMKRAMLSPRYTTRSSDLLRVK"
     gene            complement(1942..2472)
                     /gene="dsbB"
                     /locus_tag="RH288_002604"
     CDS             complement(1942..2472)
                     /gene="dsbB"
                     /locus_tag="RH288_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HDV4031650.1"
                     /translation="MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLC
                     IYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFA
                     TCDFMVRFPEWLPLDKWVPQVFVASGDCAERQWDFLGLEMPQWLLGIFIAYLIVAVLV
                     VISQPFKAKKRDLFGR"
     gene            complement(2618..4159)
                     /gene="nhaB"
                     /locus_tag="RH288_002605"
     CDS             complement(2618..4159)
                     /gene="nhaB"
                     /locus_tag="RH288_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HDV4031651.1"
                     /translation="MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKV
                     REVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLF
                     YIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMG
                     WIATL"
     gene            4380..5099
                     /gene="fadR"
                     /locus_tag="RH288_002606"
     CDS             4380..5099
                     /gene="fadR"
                     /locus_tag="RH288_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HDV4031652.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHE
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            complement(5151..6683)
                     /locus_tag="RH288_002607"
     CDS             complement(5151..6683)
                     /locus_tag="RH288_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HDV4031653.1"
                     /translation="MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIIDYLIFARKYITEC
                     EERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNLEPNIQIWNVDLR
                     GDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSIELLERCPPRMG
                     NL"
     gene            7013..8311
                     /gene="dadA"
                     /locus_tag="RH288_002608"
     CDS             7013..8311
                     /gene="dadA"
                     /locus_tag="RH288_002608"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HDV4031654.1"
                     /translation="MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYM
                     ENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDA
                     GVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKF
                     RFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMV
                     VRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQ
                     LLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS"
     gene            8321..9391
                     /gene="dadX"
                     /locus_tag="RH288_002609"
     CDS             8321..9391
                     /gene="dadX"
                     /locus_tag="RH288_002609"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HDV4031655.1"
                     /translation="MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIE
                     RIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHS
                     NWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
                     AEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPS
                     GQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAA
                     AAGTVGYELMCALALRVPVVTV"
     gene            complement(9777..11513)
                     /locus_tag="RH288_002610"
     CDS             complement(9777..11513)
                     /locus_tag="RH288_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415709.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDV4031656.1"
                     /translation="MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIAMIQHHESNISWMFIVDILQQFGLGIVIGLGGGYLLLQMINRIAL
                     PAGLYPLLALSGGILIFSLTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERV
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKV
                     VVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDN
                     QLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYA
                     DVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLK
                     IGVRVAEEEAES"
     gene            complement(11608..12522)
                     /gene="ldcA"
                     /locus_tag="RH288_002611"
     CDS             complement(11608..12522)
                     /gene="ldcA"
                     /locus_tag="RH288_002611"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HDV4031657.1"
                     /translation="MSLFHLIAPSGYCIKQHAALRGIQRLTDAGHQVNNVEVIARRCE
                     RFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLI
                     CGHSDFTAIQCGLLAHGNVITFSGPMLVANFGADELNAFTEHHFWLALRNETFTIEWQ
                     GEGPTCRAEGTLWGGNLAMLISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYH
                     AGILPRQKAIILGSFSGSTPNDYDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVT
                     LPLGAHAILNNTREGTQLTISGHPVLKM"
     gene            12622..13233
                     /gene="emtA"
                     /locus_tag="RH288_002612"
     CDS             12622..13233
                     /gene="emtA"
                     /locus_tag="RH288_002612"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415711.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HDV4031658.1"
                     /translation="MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQ
                     KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEP
                     TTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
                     RKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDAM"
     gene            complement(13235..13969)
                     /locus_tag="RH288_002613"
     CDS             complement(13235..13969)
                     /locus_tag="RH288_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HDV4031659.1"
                     /translation="MSHYHEQFLKQNPLAVLGVLRDLHKAAIPLRLSWNGGQLISKLL
                     AITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFIT
                     VPPPTLWFVQRRRYFRISAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
                     AELQEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSP
                     TVERQLQRIIFSLEREAREKADKVRD"
     gene            14170..14424
                     /locus_tag="RH288_002614"
     CDS             14170..14424
                     /locus_tag="RH288_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDV4031660.1"
                     /translation="MGIIAWIIFDLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAILVLGIFRLLRRE"
     gene            14602..15042
                     /locus_tag="RH288_002615"
     CDS             14602..15042
                     /locus_tag="RH288_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031661.1"
                     /translation="MIQKINILDSSQSGVKNGADSEAVLAALIEHLELINPSGRLSQN
                     TRSAMLQLREEEWSEFFFWLLNSLECLDYVIINLTPESKKTLMSEHRNNIQVAIDALY
                     SQRRRKSPGDESETLTRRNDAIFGNHVWQTFAQYFPPGLEKPSV"
     gene            complement(15121..16818)
                     /gene="treA"
                     /locus_tag="RH288_002616"
     CDS             complement(15121..16818)
                     /gene="treA"
                     /locus_tag="RH288_002616"
                     /EC_number="3.2.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HDV4031662.1"
                     /translation="MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILL
                     GPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPK
                     EGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWD
                     SYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELL
                     AQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTP
                     RPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVP
                     VDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYLWNDQQGWYADYDL
                     KSHKVRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAP
                     NGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGG
                     GGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQPSTKEAQPTP"
     gene            complement(17138..18556)
                     /gene="dhaM"
                     /locus_tag="RH288_002617"
     CDS             complement(17138..18556)
                     /gene="dhaM"
                     /locus_tag="RH288_002617"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaM"
                     /protein_id="HDV4031663.1"
                     /translation="MVNLVIVSHSSRLGEGVGELARQMLMSDSCKIAIAAGIDDPQNP
                     IGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPEIAAKVRLCAAPLVE
                     GTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTEISDTCPAYDEEARSLAV
                     VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLI
                     AKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSTL
                     TVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHTLLDDPELLAAASEL
                     LQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQ
                     FNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIARELGIGWICQQGEKL
                     YAIQPEETLTLDVKTQRFNRQG"
     gene            complement(18567..19199)
                     /gene="dhaL"
                     /locus_tag="RH288_002618"
     CDS             complement(18567..19199)
                     /gene="dhaL"
                     /locus_tag="RH288_002618"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase ADP-binding subunit
                     DhaL"
                     /protein_id="HDV4031664.1"
                     /translation="MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNR
                     GFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQATQARQSLT
                     LEELYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASS
                     IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE"
     gene            complement(19210..20280)
                     /gene="dhaK"
                     /locus_tag="RH288_002619"
     CDS             complement(19210..20280)
                     /gene="dhaK"
                     /locus_tag="RH288_002619"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415718.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDV4031665.1"
                     /translation="MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAG
                     KVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECAMQVDGGEGVLLI
                     IKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
                     GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIH
                     GEPGIDRRPFSSLDQTVDEMFDTLLVNGSYHRTLRFWDYQQGSWQEEQQTKQPLQSGD
                     RVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLK
                     VDDETLALWDAPVHTPALNWGK"
     gene            20508..22427
                     /gene="dhaR"
                     /locus_tag="RH288_002620"
     CDS             20508..22427
                     /gene="dhaR"
                     /locus_tag="RH288_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415719.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase operon
                     transcriptional regulator DhaR"
                     /protein_id="HDV4031666.1"
                     /translation="MSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGVTFA
                     SIYRRKKAMLTLGQAALEDAWEYMAPRECALFILDETACILSRNGDPQTLQQLSALGF
                     NDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQVLWNWAFCATPLFDSKGRLTGT
                     IALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVIS
                     WDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFE
                     SQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDDPQT
                     RRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAAL
                     AEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDA
                     RRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNN
                     KLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPE
                     HLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRK
                     MKQHGIDAGQFKRRV"
     gene            complement(22527..25283)
                     /locus_tag="RH288_002621"
     CDS             complement(22527..25283)
                     /locus_tag="RH288_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001379737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV4031667.1"
                     /translation="MIFSPLLIAADTGSQYGTNITINDGDRITGDTADPSGNLYGVMT
                     PAGNTPGNINLGNDVTVNVNDASGYAKGIIIQGKNSSLTANRLTVDVVGQTSAIGINL
                     IGDYTHADLGTGSTIKSNDDGIIIGHSSTLTATQFTIENSNGIGLTINDYGTSVDLGS
                     GSKITTDGSTGVYIGGLNGNNANGAARFTATDLTIDVQGYSAMGINVQKNSVVDLGTN
                     STIKTNGDNAHGLWSFGQVSANALTVDVTGAAANGVEVRGGTTTIGADSHISSAQGGG
                     LVTSGSDAIINFTGTAAQRNSIFSGGSYGASAQTATAVVNMQNTDITVDRNGSLALGL
                     WALSGGRITGDSLAITGAAGARGIYAMTNSQIDLTSDLVIDMSTPDQMAIATQHDDGY
                     AASRINASGRMLINGSVLSKGGLINLDMHPGSVWTGSSLSDNVNGGKLDVAMNNSVWN
                     VTSNSNLDTLALSHSTVDFASHGSTAGTFATLNVENLSGNSTFIMRADVVGEGNGVNN
                     KGDLLNISGSSAGNHVLAIRNQGSEATTGNEVLTVVKTTDGAASFSASSQVELGGYLY
                     DVRKNGTNWELYASGTVPEPTPNPEPTPAPAQPPIVNPDPTPEPAPTPKPTTTADAGG
                     NYLNVGYLLNYVENRTLMQRMGDLRNQSKDGNIWLRSYGGSLDSFASGKLSGFDMGYS
                     GIQFGGDKRLSDVMPLYVGLYIGSTHASPDYSGGDGTARSDYMGMYASYMAQNGFYSD
                     LVIKASRQKNSFHVLDSQNNGVNANGTANGMSISLEAGQRFNLSPTGYGFYIEPQTQL
                     TYSHQNEMTMKASNGLNIHLNHYESLLGRASMILGYDITAGNSQLNVYVKTGAIREFS
                     GDTEYLLNNSREKYSFKGNGWNNGVGVSAQYNKQHTFYLEADYTQGNLFDQKQVNGGY
                     RFSF"
BASE COUNT         6242 a         6318 c         6557 g         6191 t
ORIGIN      
        1 aatgcttcta ttctattttt tagccgggtg atatttttca tttctgctgg atgagcgtcg
       61 tcgccagaag gccacgtgag cacaagataa gagaacgaaa aatcagcagc ctatgcagcg
      121 acaaatattg atagcctgaa tcagtattga tctgctggca agaacagact actgtatata
      181 aaaacagtat aacttcaggc agattattat gttgtttatc aagcctgcgg atctccgcga
      241 aattgtgact tttccgctat ttagcgatct tgttcagtgt ggctttcctt caccggcagc
      301 agattacgtt gaacagcgca tcgatctgaa tcaactgttg atccagcatc ccagcgcgac
      361 ttacttcgtc aaagcaagtg gtgattctat gattgatggt ggaattagtg acggtgattt
      421 actgattgtc gatagcgcta ttaccgccag ccatggtgat attgtcatcg ctgctgttga
      481 cggcgagttt acggtgaaaa aattgcaact acgcccgacg gtacagctta ttcccatgaa
      541 cagcgcgtac tcgcccatta ccatcagtag tgaagatacg ctggatgtct ttggtgtggt
      601 gatccacgtc gttaaggcga tgcgctgatg tttgccctct gtgatgtaaa cgcgttttat
      661 gccagctgtg agacggtgtt tcgccctgat ttatggggta aaccggtggt tgtgctatcg
      721 aataatgacg gttgcgttat cgcccgaaac gctgaggcaa aggcgcttgg cgttaaaatg
      781 ggcgatccct ggttcaaaca aaaagatctg tttcgtcgct gtggcgtggt ttgctttagc
      841 agcaattatg agctttacgc agacatgagc aatcgggtga tgtcgacgct ggaagagcta
      901 tcgccccgcg tcgagattta cagtattgat gaggcattct gcgatctgac aggtgtgcgt
      961 aattgtcgcg atctgactga ttttggcaga gaaattcgcg caacggtgct acaacgtacc
     1021 catcttactg ttggtgtggg gatcgcccag accaaaacgc tggctaagct tgccaatcat
     1081 gcggcaaaaa aatggcagcg gcagacgggt ggggtggtgg atttatcaaa tctggaacgc
     1141 cagcgtaaat taatgtctgc tctccccgtg gatgacgtct gggggattgg acggcggatc
     1201 agcaaaaaac tggacgcgat ggggatcaaa accgttctcg atttggcgga tacagatatc
     1261 cggtttatcc gtaaacattt taatgtcgtg ctcgaaagaa cggtgcgtga actgcgcggc
     1321 gaaccctgtt tgcaactgga agagtttgca ccgacgaagc aggaaattat ctgttcccgc
     1381 tcgtttggtg aacgcatcac ggattatccg tcgatgcggc aggccatttg tagttacgct
     1441 gcccgggcgg cggaaaaact tcgcagcgag catcaatatt gtcggtttat ctccacgttt
     1501 attaagacgt caccatttgc gctcaatgaa ccttattacg gcaatagcgc gtcggtaaaa
     1561 ctgctgacgc ccactcagga cagcagggat atcattaacg ctgctacgcg atctctggat
     1621 gccatctggc aagcgggcca tcgttaccaa aaagcgggcg tgatgctggg ggatttcttc
     1681 agtcagggag tcgcgcagct caatttattc gatgacaacg caccgcgccc cgggagtgag
     1741 caattgatga cggtaatgga tacactgaat gctaaagagg gcagaggaac actctatttt
     1801 gccgggcagg ggatccagca acaatggcag atgaagcgag ccatgctttc accacgttat
     1861 acaacgcgaa gttctgattt actgagggtc aaataaatat agcggcagga aaaaagcgct
     1921 cccgcaggag cgccgaatgg attagcgacc gaacagatca cgttttttcg ctttaaacgg
     1981 ctgggaaatc accaccagca ctgcgacaat caggtaagcg ataaaaatac cgagcagcca
     2041 ctgcggcatt tccagaccta aaaaatccca ctgacgctcg gcgcaatcgc cagaggcgac
     2101 aaacacttgc ggcacccact tatccagcgg cagccattcc gggaaacgaa ccataaaatc
     2161 acaggtggca aacggcgaag gatagagctg aagcatggtg tgctcgtaag ttaactgcac
     2221 accgcggaac gcactataca accagataac catcgctaca taacgcagcg gagttttcgg
     2281 ggcgatcgcg ccaatcagcg cagcacccag aacgccgaat aacgcgcagc gttcataaat
     2341 acagagcacg caaggtttca gtaacatcac atgctggaac cacagcgccg tcagttccag
     2401 tgccagagca gtaaacgcca tcaacagcca cgcgccccgg ccttgtgaac attggttcaa
     2461 aaatcgcaac ataatcattt ccctgcaata tgcatagagt gcgcagttta aaccaattca
     2521 ttcgctgcgc caccaggagg cagcaaaaat aggacgcaat tggacaatta tcgggcgaaa
     2581 aggcaaaccg ggcatttata tgcccggtaa gttgttatca aagcgttgct atccagccca
     2641 tttgcataaa ccattcggtt acaggggcaa gcgtaaactc gacgcagagc aagccgacga
     2701 gtgtcaggac gagggtgtaa ggcagggcca tccacaccat gcggccataa gagaggcgaa
     2761 tcaatggcgc gagtgcagag gtcagcagga acaggaacgc agcctgaccg ttcggcgtag
     2821 cgacggaggg cagattggta ccggtattaa tggcgaccgc cagcagctcg tattgcttca
     2881 acgtgatagc gccactttcc attgccgctt tcgcttcgtt gatataaatc gtccccacga
     2941 agacgttatc cgaaatggat gacagcagac cgttgaaaat atagaacagc gacagctgag
     3001 catgttccga tgcctgcaac acaaactgaa taattggcga aaacagttgt tggtcgataa
     3061 tcaccgcgac taccgagaaa aacaccgtca acagtgcggt gaatggcaga gattcggtga
     3121 aggctttacc gatagcatgc tcatcggtga caccggtcaa tgatgttgcc agaataatga
     3181 ctgacaaacc aatcaagcca acttccgcca gatgcaacgc cagcgcagtc accagccaga
     3241 cgccaataat cgcctggaca atcagacgga ttttatcctg acgggtacgc tggtggcggc
     3301 tttgatcgtc aaactgttgc aacacttcgc ggactttctc cggcagcgtt tcaccgtagc
     3361 caaaccaacg cagcttctct accagcaggc aggttaacag gccacaaatc agaaccggaa
     3421 cggtcaccgg cgacatgcgc aggaagaaat cgccaaaatg ccagccagcc gctttagcga
     3481 tgatcaggtt ctgtggttcg cccaccatgg tcattacgcc gcctaatgcg gtgccgacac
     3541 cggcatgcat catcaggcta cgcagaaagc cacggaactg ttccagaacc actttgtaat
     3601 gcttgtcgat atgactatcg tcttgcaggt cggtgtcttc ggtacgggaa gaggctacgc
     3661 ggtgataaat accataaaaa ccgactgcaa cgctgatcac caccgccacg acggttaagg
     3721 catcgaggaa cgcggagagg aacgcagccg ccacgcaaaa agagagcgac agcagcattt
     3781 tggagcgaat gcttaacagc aaacgggtaa atatgaacag caacagctgt ttcataaaat
     3841 agatacccgc caccataaac atcagtaaca gcaagacttc aagatttgcc gccacctctt
     3901 cacggacgtg ttccgcgctg gtcatgccga tgaataccgc ttcgatagcc aacagaccac
     3961 cggggagcag cgggtagcat ttcagggcca tcgccagagt gaaaataaat tccgctacca
     4021 gcaaccagcc cgcgacgaaa gggctgatga ggaaaattaa cgggtttacg attaagaaaa
     4081 tgatgagggc gagtttgtac cagtcggggg actggcccaa aaaattgcgc catagcgcgc
     4141 ggccccagga gatctccatg atggtttccc ttaccttaca aataatcaat gatgttttta
     4201 tgtttaaacg caaagcttaa cggtcaggca ggagtgaggc aagtcttgat agtcaagggg
     4261 aaagagatgc ggaaaatgaa gccttgatcc ctttttcttc tttttgtctg ctatcagcgt
     4321 agttagccct ctggtatgat gagtccaact ttgttttgct gtgttatgga aatctcacta
     4381 tggtcattaa ggcgcaaagc ccggcgggtt tcgcggaaga gtacattatt gaaagtatct
     4441 ggaataaccg cttccctccc gggactattt tgcccgcaga acgtgaactt tcagaattaa
     4501 ttggcgtaac gcgtactacg ttacgtgaag tgttacagcg tctggcacga gatggctggt
     4561 tgaccattca acatggcaag ccgacgaagg tgaataattt ctgggaaact tccggtttaa
     4621 atatccttga aacactggcg cgactggatc acgaaagtgt gccgcagctt attgataatt
     4681 tgctgtcggt gcgtaccaat atttccacta tttttattcg caccgcgttt cgtcagcatc
     4741 ccgataaagc gcaggaagtg ctggctaccg ctaatgaagt ggccgatcac gccgatgcct
     4801 ttgccgagct ggattacaac atattccgcg gcctggcgtt tgcttccggc aacccgattt
     4861 acggtctgat tcttaacggg atgaaagggc tgtatacgcg tattggtcgt cactatttcg
     4921 ccaatccgga agcgcgcagt ctggcgctgg gcttctacca caaactgtcg gcgttgtgca
     4981 gtgaaggcgc gcacgatcag gtgtacgaaa cagtgcgtcg ctatgggcat gagagtggcg
     5041 agatttggca ccggatgcag aaaaatctgc cgggtgattt agccattcag gggcgataat
     5101 cccttccgtt taaagagcaa acccctcaaa cgaggggttt tttgttgttt ttacagattt
     5161 cccattcttg gcgggcaacg ttccagcaac tcgatgctgc cgtcttcgtt ttgctgttcg
     5221 agcatcacat caaatcccca caggcgatgc acatgcttca ggacttcttt gcgcccccga
     5281 tccagcggtg cgcgattatg tggaatataa cgcagcgtca gcgaacggtc gccgcgcaaa
     5341 tccacgttcc agatctgaat attcggctcc agattactta agttatattg cgacgataac
     5401 cggttacgga tctcccgata accttcttca ttatgaatag cggaaatctc cagataatta
     5461 tgccgatcgt catccagcac ggtgaagaag cggaaatcac gcatcacttt cggtgacagg
     5521 aactggctga taaaactctc atctttgaaa tcacgcatcg cgaaatgcag cgtttccagc
     5581 cagtcggaac cggcgatatc cgggaaccag tatttgtctt cttccgttgg cgactgacaa
     5641 atccgtttaa tatcctggaa catggcgaac ccgagggcat acgggttgat gccgctgtac
     5701 cacgggctgt tatagggggg ctggaagacc acattggtgt ggctgtgcaa aaactccagc
     5761 ataaaacgtt ccgttacttt cccttcatca tacagatggt taaggatggt gtagtgccag
     5821 aaggtcgccc agccttcgtt catcacctga gtctgttttt gcggataaaa atactggctc
     5881 accttacgca caatacgcag gatttcacgc tgccatgatt ccagcagtgg cgcatttttc
     5941 tccataaaat agagcaggtt ttcttgtggt tcggacggat agcggcgcgc ttcagcaacc
     6001 gttttctctt cctcgcgctt cggcagggta cgccagagca tattgacctg actttgcaga
     6061 tactcttcgc gacttttctg ccgggctttc tcttcttgca gcgagatttt ttgcgggcgt
     6121 ttgtaccggt ccacgccgta gttcatcagc gcgtggcacg agtccagaag ccgttctact
     6181 tcatcaacgc cataacgctc ttcgcactcg gtaatatatt tacgggcaaa aatcagataa
     6241 tcgataatcg aactggcgtc ggtccagcta cggaataagt aattgttttt gaagaaagag
     6301 ttatgcccat agcaggcatg agccatcacc agcgcttgca tggtaatggt gttctcttcc
     6361 atcaggtaag cgatacacgg gttagagtta atgacgattt cataggccag tccttgctga
     6421 ccgtgcttat acagccgttc agtctcgata aactttttac cgaatgacca gtgcggatag
     6481 ttaattggca tgccgacgct ggagtaggca tccatcatct gttctgaggt tatcacttca
     6541 atctggtgcg ggtaggtatc cagccggtag agtttcgcca cccggtctat ctctgccaga
     6601 taaacatcca gcaggtcgaa cgtccagtcg ggtccatcgc tcaaacgtgt ggtgtcctta
     6661 ttcatagaat cgatcgtcgc catacgcgca cctcattgtt gtcggcgctc tctgtgtgga
     6721 gcacctcatt tcaagcatag aacacctgtt aaaaaccgcg tcgccggaga atttttttct
     6781 ttgcgatttc ttattatcag agtgccacta atccgcttct gaacggaatt ttatgctgga
     6841 taaaaagggc gttcagcagg agatactaaa gacgccatat tgccgcagag tcagggagat
     6901 gtgagccagc tcaccataaa aaagccgtat gttgaataat attttcaact gagttatcaa
     6961 gatgtgatta gattattatt cttttactgt atctaccgtt atcggagtgg ctatgcgagt
     7021 tgtcatactg ggaagtggtg tggtaggcgt tgccagcgcc tggtacttaa atcaggcagg
     7081 acatgaggtc accgtcattg atcgggagcc gggggccgcc ctggaaacca gtgccgcgaa
     7141 tgccgggcaa atctcccccg gatatgctgc accgtgggcg gcaccaggtg tgcctttaaa
     7201 agcgattaaa tggatgttcc agcgccatgc gccgctggcg gttcgtctcg acggtacgca
     7261 gttccagttg aaatggatgt ggcaaatgtt acgtaactgc gacaccagcc actacatgga
     7321 aaacaaaggg cggatggtgc gtctggcgga atacagccgt gattgcctga aagcattgcg
     7381 cgccgaaacc aatattcagt atgaagggcg tcagggtggg acgctgcaac tgttccgtac
     7441 cgaacaacag tatgaaaatg cgacccgcga tatcgccgtg ctggaagatg ccggcgtacc
     7501 gtatcagctg ctggaatcca gccgcctggc ggaagtggag cccgcgctgg cagaagtggc
     7561 gcacaaactg acgggcggcc tgcagttacc caatgatgaa accggagact gtcagctatt
     7621 tacccagaat ctggcgcgga tggcggagca ggcgggggtt aaattccgct ttaatacgcc
     7681 cgttgaccaa ctgctttgcg acggcgagca aatctacggc gtgaagtgtg gcgatgaagt
     7741 gattaaggcc gatgcgtatg tgatggcgtt tggttcttac tcgacggcga tgctcaaagg
     7801 cattgttgat attccggtgt atccgctgaa aggctactcg ctgaccattc caattgcgca
     7861 ggaagatggt gcgccggtat ccaccattct tgatgaaacc tacaaaatcg ccattacccg
     7921 tttcgataac cgcattcgtg ttggcggaat ggcggagatt gttggtttta ataccgagct
     7981 gttgcaaccg cgtcgtgaaa cgctggagat ggtggttcgc gatctctatc cacgcggcgg
     8041 tcatgtcgag caggcgactt tctggactgg tctgcgcccg atgacgccag acggcacgcc
     8101 ggttgtcggg cgtacacgct ttaaaaatct gtggctgaat accggtcacg gcacgctcgg
     8161 ctggacgatg gcttgcggtt ccggtcagtt gttaagcgat ctgctctctg gtcgcacgcc
     8221 agcgatccca tatgaggatc taagcgtagc gcgctacagc cgtggattta cgccatcacg
     8281 tccgggccat ttacatggcg cacacagcta aggaaacgag atgacccgtc cgatacaggc
     8341 cagcctcgat ctgcaggcat taaaacagaa tctgtccatt gtccgccagg ccgcgacgca
     8401 cgcgcgcgtc tggtcggtgg taaaagcgaa cgcttacggg catggtattg agcgtatctg
     8461 gagcgcgatc ggggccaccg atggctttgc attgcttaac ctggaagagg caataacgtt
     8521 acgtgagcgc ggctggaaag gaccgatcct gatgctggaa ggatttttcc atgctcagga
     8581 tctggagatt tatgaccagc accgcctgac cacctgcgta cacagcaact ggcagctcaa
     8641 agcactgcaa aatgcgcggc taaaagcacc gttggatatt tatcttaaag tgaacagtgg
     8701 gatgaatcgg ttgggcttcc agcccgatcg cgtgcttacc gtctggcagc agttgcgggc
     8761 aatggcgaat gttggcgaaa tgaccctgat gtcgcatttt gccgaagcgg aacatcctga
     8821 tggaatttcc ggcgcgatgg cgcgtattga gcaggcggcg gaggggctgg agtgtcggcg
     8881 ttcgttgtcc aattcggcgg cgactctgtg gcacccggaa gcgcattttg actgggttcg
     8941 gcctggcatt attttgtatg gcgcttcgcc gtccggtcag tggcgtgata tcgccaatac
     9001 cggattacgt ccggtgatga cgctaagcag tgagattatt ggtgtccaga cgctaaaagc
     9061 gggcgagcgt gtgggctacg gcggtcgcta tactgcgcgc gatgaacagc gaatcggcat
     9121 tgtcgccgca gggtacgccg acggttatcc gcgccacgcg cctaccggta cccctgtttt
     9181 agtggacggc gtgcgcacca tgacggtggg gaccgtctcg atggatatgc tagcggtcga
     9241 tttaacgcct tgcccgcagg cgggtattgg tacgccggtt gagctgtggg gcaaggagat
     9301 caaaattgat gatgtcgccg ccgctgccgg aacggtgggc tatgagttga tgtgcgcgct
     9361 ggcgctacgc gtcccggttg tgacggtgta acttgttgta agccggatcg gaggcaacgt
     9421 cttctgggtg caaaaaaatc atccatccgg ctggtcagca actgtagttg ttaatgtgac
     9481 agagccattg cccatgatag tgtccattaa aaggatggac actatttccc cggaacctga
     9541 actcaccgca caggcgttct acataaaacg cttacgcttc attgttgact cgaactcgac
     9601 ttcagataaa tcacgcttta cccttgatgg agcctgtaca tagatttgtg taattgcctg
     9661 attttgatat gttcaattca acatcaaatg aaggttaaat tatggacgac aaacaattgc
     9721 aggctcaggc tgcgttcagc aaagcatcgc aaccggcgat agatgcttca ttaaatttaa
     9781 gattcagctt cctcttcagc cacccgtacg ccaatcttca acacttcatt atcttctttc
     9841 tcggccaccg tccagatcat cccggcaaac tctacctggt caccgacaac cggtgccgcg
     9901 cctaacaact gctggacaat ttcacccagc gtttgctgct tatcacgata ttctcgcccg
     9961 tcttccaggc catatatcag cgcaacatca gcatatttgg cgctggcttc gagaatgaag
    10021 tcaccaaaga agcgttgatc cagcgcgacc ggcggcgact ggctgaacag tttaccgagc
    10081 gccggaagat cgcgttcccg accaattaca cacaacacat cgccttcgcg cagtcgggtg
    10141 ctgccggtag gatgaagcaa ctggttatca cgaaacagtg ccgcaatacg cgtctctttt
    10201 ggcatatgca aatcgcgcag tgccgcgccc acgcaccatt tatcggcact caattgataa
    10261 acaaactgct cccacggatt ttccggatga atatccaggc caacgcgtga caccggacgt
    10321 cccactggcg gaaccaccac tttggctttt ttagccgccc acgagagtga tgttccctgc
    10381 aagagcagtg aaaccagaac cacaaagaag gcgacattaa agaacagacg tgcattctcc
    10441 agccccgcca tcatcgggaa cacggccagg atgattggca ccgcgccgcg taatcctacc
    10501 cagctgataa acacgcgctc acgcagattg aaaccgcgga aggggagcaa tccagcaaat
    10561 accgaaaggg gacgggcgaa gaatatcatc catgcggaca aaatgagcgc cggaatggca
    10621 ataggcagca gatcgcttgg gttaaccaac agccccagca ccaggaacat ggcgatttgc
    10681 gccagccagg cgaggccgtc gaaattttgc aggatgccgt agcggttgcg aatagggcga
    10741 ttacccagca gaaaaccgca cagatacacc gccagaatac cgctaccttc cagcgcagta
    10801 gttaatgaga aaatcagaat accgccactt aatgccagca atggatataa tccggcgggc
    10861 agggcgatgc ggttgatcat ttgcagtagt aaataaccgc cgccaagacc tattacaatg
    10921 cccagaccaa attgttgcag aatatcgaca atgaacatcc agctaatatt gctctcatga
    10981 tgctggatca tcgcaattag ggtaatcgtc agaaagaccg ccattggatc attactgccg
    11041 gattcaattt ccagcgtcga gccaacacgt tcgttaagcc ccttaccacc cagcagagaa
    11101 aagaccgctg cagcatcggt agagccgacg atagcgccga ttaataagcc ttcaatcaaa
    11161 tcaagattaa acagccacgc cgccatcatg ccggttaaac cagaggtgat aagcacgccc
    11221 agcgtcgcca gcgacagtgc cggtcctaac gccacacgaa aggaactggc ctgagtgcgc
    11281 atcccgccgt cgagcaaaat aatcgccagt gccaggttac ttaccatgta ggcgaagggg
    11341 taattatcaa acgggatacc gccgacgcca tcgactcctg ccagcatgcc gatcgccaga
    11401 aaaataacca gaataggaat gccaagacgg gaagaaaatg aactaagtaa tatactgctg
    11461 gtgacaagga tggatcctaa gatgaaaagg ctaattattg ttgtggcatc caacggtcgg
    11521 ttactcctga ttacgctgtc tcttatataa accctaccat attagcggca gagacagcgt
    11581 tttacttagc cctgaagcgt gattttttta cattttaaga acaggatgac cgctaatcgt
    11641 caactgagtg ccttcccggg tgttattcag aatggcatgt gcgcccaacg gcagcgtaac
    11701 cgtgcgttgt tcatgaccaa aatcgaggcc ggtaatgagt ggaatcgaca ggcgggaacg
    11761 caaaaacgcg tacactgact ccaggttgta acctgcgtca taatcattgg gcgtgctgcc
    11821 gctaaagcta ccgagaataa tcgccttctg acgtggcaaa attcccgcat gatagagctg
    11881 caacagcata cgttcgaccc ggaaagggtg ctcgttaata tcttccagca ccagaatacc
    11941 gttctcaatt tttggcatcc acggtgtacc gatcagtgaa atcagcatcg caagattgcc
    12001 tccccacaac gtgccttcgg cccgacatgt cgggccttcc ccttgccatt caatggtgaa
    12061 ggtttcattg cgtaacgcca gccagaaatg gtgctcggta aaggcgttca gttcatccgc
    12121 gccaaagttt gctaccagca tggggccgct aaaggtgatg acattgccat gcgccagaag
    12181 accgcactga atggcggtaa aatcgctatg tccgcaaatg agcaacgggt catgttgttg
    12241 gcgagccacc agtgcctgcc agtcaatatc tgccagtaaa cgactggcac cgtaaccgcc
    12301 gcgtacagcc agcacgatgg tgttgggggt agtcagtctg gcaagggaat tgagatcttc
    12361 cagacgctct gtttccgtac ccgcaaaacg ctcacaacga cgggcaataa cctcgacgtt
    12421 attgacttga tgccccgcgt cggtaaggcg ctggatacca cgcagcgcgg cgtgctgttt
    12481 aatgcagtaa cccgatgggg caattaagtg aaacagagac atggcaattc cttgctgaca
    12541 acagaaacga aatgtatatc atgccgctta ggtgtgccgt tgtcacctca acggcgattc
    12601 caggctataa ggatagaaga agtgaaattg agatggtttg cctttttgat tgtgttatta
    12661 gcgggttgtt catcaaagca tgactatacg aacccgccgt ggaacgcgaa agttccggtg
    12721 caacgtgcga tgcagtggat gccaataagc cagaaagccg gtgcagcctg gggcgtcgat
    12781 ccacaattga tcacggcgat tatcgctatc gaatcgggtg gtaatccgaa cgcggtgagt
    12841 aaatcgaatg ccattggttt gatgcagtta aaagcttcaa cctccggacg tgatgtttat
    12901 cgccgtatgg gctggagtgg tgagccgacg accagcgagc tgaaaaatcc agagcgtaat
    12961 atttcaatgg gggcggctta cctgaatatt ctggaaaccg gcccgctggc aggcattgaa
    13021 gatccgaagg tactgcaata tgcgctggtg gtgtcatacg ctaacggggc aggtgcgctg
    13081 ctacggactt tctcgtcaga tcggaaaaag gcgatcagca aaatcaacga tttggatgct
    13141 gacgagttcc tcgaacacgt agcgcgaaat caccctgcgc cgcaggctcc gcgctatatc
    13201 tacaaacttg agcaggcact ggacgcgatg taaatcagtc gcgcactttg tccgcttttt
    13261 cccgggcttc tcgctcgaga gagaaaataa tccgctgtaa ttgccgctcc accgtcgggc
    13321 tgacgttaag aaaacggaag ctcagacggg gagtggtgat ggtttcattc ttgccatcaa
    13381 tcactttgcg ctcgctgatg gagattaact gggcgtcaaa gtgaaaaaca ccccattgcc
    13441 ccatgttgac ttcaatctga gcgaagcgca tgccttcttg taattcggca ggctttgctg
    13501 tttccagtaa tgcgcccatg ccgcctaacg acaaatcata caggcggaaa cgtaacgtac
    13561 tgttatccgc cagtttggtc tggcaaaaat aaggcggatg gagtggggcg gagatgcgga
    13621 aatatcggcg tcgttgtaca aaccataagg tgggaggcgg tacggtaata aatgccggaa
    13681 gctgcaagta ttcactctgc tgtagttgtt caacagtaaa ctcgactttc gcaccctgag
    13741 tttcggcggt aatggtaatg tgctgtgcct ttagcacggc gatgttgtct tcggcttgac
    13801 tgccgaaatc cagcaccagt ttatccgggg ttattgccag taatttgctg atcagctgcc
    13861 cgccattcca actgagacgc aaaggaattg cggctttgtg caaatcgcgt aacacgccca
    13921 ggacggctaa cggattttgt ttcaggaact gctcatggta atgactcacg cggaaaaact
    13981 cctgactgac aaactgtctt tggtttatcg gtcacagtta acaaaactta atacaaatgc
    14041 gtgaatattt tttacatgtt gttcttaaat cagccgacat acgcccagca tcgatcccgc
    14101 ccttgcctat acttagagcg ttgatgtaag catttcttgc gtccgattca tcgaaacgag
    14161 ggcctgaaca tgggaattat tgcctggatt atttttgacc tgatagccgg cattatcgcc
    14221 aagctaatca tgccggggcg tgatggtggt ggatttttcc tgacctgtat tctcgggata
    14281 gtcggtgcgg tggtcggcgg ctggctggcg accatgtttg gcattggcgg ctccatcagt
    14341 ggttttaatc tgcacagctt cctggtggcg gtggtgggag ctattctcgt tctgggcata
    14401 ttccgcctcc tgcgaagaga ataagatttt cataaggcgg atagcgatac agatgccgct
    14461 atccgctttc acatcagaac gtatactcga cacctgcttt acgggtgaaa aaaatcaata
    14521 tagcacttcg atatccgata aagtcggttc ccggtaacaa caacagaatc cttttttaat
    14581 tattgtttcg ttgtttttgg tgtgattcag aaaataaata ttttagacag tagccagtca
    14641 ggcgttaaaa atggggcgga tagtgaggcg gttttggctg cgcttattga acatttagaa
    14701 ttgatcaatc cttctggcag attaagccaa aatacccgtt cggcaatgct tcagttacgc
    14761 gaagaggaat ggtctgaatt ctttttttgg ttgctaaatt ctctggagtg tctggattat
    14821 gtgattatta atttaactcc agaaagcaaa aaaacgttga tgagtgaaca ccgtaacaat
    14881 attcaggtag caattgatgc tttatatagc caacgtcggc gtaaatcgcc gggtgatgaa
    14941 agtgaaacac ttacccgtag aaatgacgct atcttcggca accacgtatg gcaaacattt
    15001 gcgcaatact tcccgccagg acttgaaaaa ccgtctgtgt agaaaaaacc atagctatgg
    15061 tgttatctgc cgacaacgcc atccggagaa gccgaatgac gttgtcggag taagcgctgg
    15121 ttaaggtgtg ggttgtgcct ctttggttga gggttgcgtc gttgctgact taacggtcgg
    15181 acgcgtcgcc ggaacattgt cacacggttg ctctttcggg cagatcaaat ccagcatttt
    15241 cagcgtcacg ccattggtcc agccaaagcc atcctgtaat ggatattcgc caccgccgcc
    15301 ccccgttccg gtggtgctga catcatattt ttccaccagc tttttctccc ggtcataggt
    15361 gtgctgaaca ttggtcagga agtgccagct aatgtccatc gccacctctt tttgcccgta
    15421 gttttgtaat ccttctgtcg cgacccactg taacggtgcc cagccatttg gcgcatccca
    15481 ttgttgccca cttttcaccg acgtggtgtt caggccgccg ggttgcagca gatgtgtttt
    15541 cgtcgccgtc gccattttgt tggcgcgatc tttcgctgcc gcattgacgt acagcgggaa
    15601 cagggcggcc gcggttaact gattgcgcac tttatgactt ttcaggtcgt aatcggcata
    15661 ccagccttgt tgatcgttcc acaggtattt ttcgatccct ttttgacggg catttgccag
    15721 cgtttcgtac tggtttgcca tcgcgttatc tccggcagct ttgctggcgc gggcgaggat
    15781 tttttccatt ttaaacatca ggctgttcag atcgaccggt acgatgctgg tggtgcgtaa
    15841 ggtatttaac tgctgcgggt tgtccatcca gcgcgagctg aaatcccagc cagacgcagc
    15901 ggcagagcgc aggtcgcggt aaatttcagt ggcaggtcga ttcggattgc ttttggcggt
    15961 ggcaatatct tccacccatg actctggtcg tggcgtatcg cgatcgtccc agtagcggtt
    16021 gagaagggta ccatcctgaa gtttgacaac gcgtttttcc tgttgtccgg cttgcaggtt
    16081 ttcaacaccg tccatccagt aagcatattc tttttgcatt tgcggcaggt attgcttcaa
    16141 cgcggcatcg ccttcatgct gcgccagtaa ctctaccatc agggcaaaga agggcggttg
    16201 cgagcggctt aaatagtaac tgcggttgcc gttgggaata tgaccgtaag tgtctatttc
    16261 atgagcaaaa ttggccacca tatccgcgac tttatcccag tgaccgcttt cggcaagtcc
    16321 taacatggtg aagtaactgt cccagtaata tacctcgcga aagcgtccgc ccggcacgac
    16381 ataaggttcc ggcagcggta acagagaatc ccatttttcg gtgttttcgg tagaacgcgt
    16441 taataccggc caaagtccgt caatatgttc gcgcagtgac tgcccctctg gcggaacata
    16501 tttctcgcct tctttcggca gggtgaaatt gacgttaacg aaatggcgca gatcaaatcc
    16561 gctctggttt tgctgcatcc gataatcagc aaggatcatc agcggatcgc tgttcggcac
    16621 ggcatcggca aaggtttttt ggtccggaaa aagtttggcg ttttgcacat cattaaacag
    16681 cggccctaat aaaatatcag gcggctgtgg tgttaccggt gtttcttctg cctgcaccga
    16741 tagcgcagcg aaacacaaaa agatacaggc tggaattaac gccatttttt gcgggcgaga
    16801 aggtgcgggg gatttcatca atcattctcc tttggcgaaa ccgaataaaa cggtattcaa
    16861 gtatcagaaa accttagttc aggatcgcac tagctgcatg atcgaaatct cattctgcga
    16921 actgtcaggc attttagaaa agggaattaa agggataaat aacggcgaaa tagagtgatc
    16981 aaataacgtc tgtttattag ccagccagcg gcgttgggtt cgtgattagc gaagaaaaat
    17041 catcataaat tggtgaaaaa tataacaggt agttaaaaac cattagtgct gagtaaattg
    17101 ccggatgaca tcagaacgat gccatccgaa cagtggctta accctgacgg ttgaaacgtt
    17161 gcgttttaac gtccagcgtt agcgtttctt ctggttgtat cgcatacagt ttctcaccct
    17221 gctggcaaat ccagccaatc cccagttcac gggcgattag ggcgctgtgg gataccggac
    17281 ttccggcgct aaggcagata ccttttacaa ccgccggatc cagttgcagt actgtggaag
    17341 gataaatgtt ctccgccagt agaatagttg gcgagttaaa ctgcgggagt tcttctttcg
    17401 tttgggtcag gtggaccagg gtgcgatgca gaagatcgtc cacatcaata tagcgagctt
    17461 gtagatattc atcatccagt tgctggtatt gctggctaag ttctttaaga acttgctgcc
    17521 aagcatattc tgccgtgcaa tgttcatgct gaaggagttc gcttgccgcc gccagcagtt
    17581 ccggatcatc taacagtgta tggtgaccag aaaagattgc ggcaatatcg tcaagcccgc
    17641 tggcttctgc tttcgctgtt aacgtcatca gatctaataa cgtgaagtca atagcctggc
    17701 gtaatcgatc ttgttcttct tccacggtca gggttgattt tgcctgtacc gtacataaaa
    17761 ctggttgata ataaaaggct ttacccgaaa caggcggaac gggacgcaga gtaggtggag
    17821 cgacttcctc cgtttcacca aagttatctt cagccagctg acggaaagcg atcagtgcct
    17881 cttcagcttc tggccctttc gcaatcaggc gcagcgtatc gttatagcga acttgtagta
    17941 acgcaatctg gttaatactc tctggtgtga cgcatttgcc gtttttttcc agcaacatat
    18001 cggcattaaa tgtcgataag gtataaacca gccgggaggc cggacgtaca tgcaggccgt
    18061 tacggttttt tatgaccacc gccagagaac gggcttcttc atcgtacgca ggacatgtgt
    18121 cagagatttc agtgtcggag gacggtaaac ccagttgttc acgtttggct tccagcgcat
    18181 gcatggcgtc aaagataact ttgtcgatat ccgcccccga ggccgcgctg accgttgctg
    18241 ccagtgtacc ttcgaccaac ggcgcagcac acaaacgtac ttttgcggcg atctcgggag
    18301 ccagcaattc cagcgcagtt tcagcactca ataatgcgct acccatatcc atcatgacca
    18361 gcacatggtc ggcatcagca acagattcga tggcctccat cactttgacg gcatcggtac
    18421 caatgggatt ttgtggatcg tcaattcccg cggcaatggc gattttacaa ctatcactca
    18481 ttaacatctg acgggctaat tcaccgacac cttctcccag tcggctgcta tgtgaaacta
    18541 tgaccaggtt taccatcacc aattccttac tcttttgcgg ctaacgccaa catttgcatc
    18601 ataaacatca ccgaggtcgc gccgggatcc tggtgaccaa tactgcgttc accgagataa
    18661 ctggcgcggc ctttgcgggc ttgcatcgta atcgtacttt gtgcagcgga ttcggcgatg
    18721 ctactggcag cttcgagcgc caccggaaca gagagatttt gctcgctgga ctgacgtaac
    18781 gattccacca ccggcaccca cacatcacac atggttttat cgccaggttc ggctttcccg
    18841 cgactgatta cgccgtccgc gccatcgcgg aacatctgat aaagctcttc cagtgtcagg
    18901 ctttgccgtg cctgggtcgc ctgtgcggcg cggataaaga aggtaccgaa cagcggacca
    18961 ctggcaccac cgacgctgga aagcagcgtc ataccggtat tcttgagaat gaaaccgata
    19021 tctttatctg cgatagcagg gagtttttcc accactttgc taaagcctcg gttcatattt
    19081 agcccgtggt cagcatcgcc aatttcgcga tccagtccgg taagatactc gctctcggtg
    19141 ctgaaaatat cgccacaacg agtgagccag ttaacaattt gagttctgct cagtgacatt
    19201 gctttctcct tatttacccc agttaagggc cggggtgtgg accggggcgt cccagagtgc
    19261 cagcgtttcg tcatcaactt tcagtaaggt gattgagaaa ccggtcatat ccagtgaggt
    19321 gcagtacgcg ccaattaaat tacgttcgat agtcaatccc gcttgctggc aacgtgtggt
    19381 caggcggtta tagacgccgt acagctcaga aagcggagtt gcgccaagat tgttaaccag
    19441 cgcaatcacc cgatcgccag actggagcgg ttgtttggtt tgttgttctt cctgccaact
    19501 gccttgttga taatcccaga aacgcaaagt gcgatggtat gagccattta ccagcagggt
    19561 gtcgaacatt tcatcgacgg tttgatcaag ggaagagaag gggcggcggt caatacccgg
    19621 ctcaccatga atgccgacgc caaactccat ctcattatcc gccagggtaa aagaaggttt
    19681 gcccgcggca ggaacggtac aggcaccgag agcgatacct attgagtggc cttgattatt
    19741 cagcttacgc cccagttccg cacaggcgtc cagtgagtcg ccacgctccg ccgctgcgcc
    19801 tacgagtttt tcaattaata cggtgttggc aacgccgcgt cgcccggcag tataaagact
    19861 gtcttttacc gcaacgtcgt catcaatgac cacagtggtc acttttacgc cgctatcgtg
    19921 cagtaactcg gtcgctgttt caaagttaag aatatcgccg gtgtaatttt tgataatcaa
    19981 cagtacacct tcgccgccat caacttgcat ggcgcattca aagattttat cgggcgtcgg
    20041 tgaggtgaaa atttcgcccg gacaggcccc cgaaagcatc ccctgaccga tataaccaca
    20101 gtgcatcggc tcgtgtccgc tgccgccacc cgacagcagg gcgacttttc ctgcaacagg
    20161 ggcatcagct cgggtgacat acaccggatc ctgatgcagt gtcagcgatg gatgcgcttt
    20221 cgccagtcct gccagttgtt cgtccagtac gtcttgcaca tcattgatca attttttcat
    20281 tattttgctc cagcaattac ggtagggcat ggatgatgtt caacgacacg gcgaccactg
    20341 actgccgatg aatccattgt gcatcaggca agggaaaaga aaattagccc aaattatgtt
    20401 tcatagtgaa acatatgctt taatgaatgt tccatattga aacttttacg tgtattaata
    20461 cttaaaattg cgagccggaa caccttttgt cataagggat gcgggatatg agtggcgctt
    20521 ttaacaacga tggtcggggc atatctccct taattgcaac ctcctgggag cgatgcaata
    20581 agctgatgaa acgggagaca tggaacgtac cacatcaggc ccagggcgtg acatttgctt
    20641 ctatttatcg gcgtaagaaa gcgatgctga cgctcgggca ggctgcgctg gaagatgcct
    20701 gggaatatat ggcaccgcga gagtgtgcgc tgtttatcct cgatgaaacc gcctgcattc
    20761 tcagccgtaa tggcgatccg caaaccttgc agcagctaag tgcactggga ttcaatgacg
    20821 gcacgtattg cgccgaggga attattggta cttgtgcgct atcgttagcg gctatctctg
    20881 gtcaggccgt gaaaacgatg gccgatcaac atttcaaaca ggtactctgg aactgggcct
    20941 tttgtgcaac gccgttgttt gacagcaagg gccgattgac gggaacaata gcgctggcgt
    21001 gtccggttga gcaaactacc gcagctgatt tgccgttgac gttggcaatc gcccgcgagg
    21061 tcggaaattt actgctgacg gacagtttgc tcgctgaaac taaccgtcat ttaaatcaac
    21121 ttaatgccct gttagaaagt atggatgatg gcgtgattag ctgggacgag cagggtaatt
    21181 tgcaatttat taatgcccag gcggcgcggg tcttgcgcct tgacgcgacg gcaagtcagg
    21241 gacgggcaat cactgaactc ttaacgttac ccgccgtatt gcaacaagca ataaaacagg
    21301 cacatccgct caaacacgta gaagcaacct ttgaaagcca gcaccagttt attgatgcgg
    21361 tgataaccct taaaccgata atagaaacgc agggaaccag ctttattttg ttgctccatc
    21421 ctgtggaaca gatgcggcag ttgatgacca gtcaattagg aaaagtcagc cataccttcg
    21481 ctcatatgcc acaggacgat ccgcaaaccc gccgcttgat tcattttggt cgccaggcgg
    21541 cgcgcagtag ctttcctgtc ctgctttgtg gagaagaggg cgtgggcaag gcactgctaa
    21601 gtcaggcaat tcataatgaa agcgagcgtg ctgcaggtcc ttatatcgcc gtcaattgtg
    21661 agttatatgg tgatgctgcg ctggcggaag aatttattgg tggcgatcgc acggacaatg
    21721 aaaatggccg tctgagtcgg ctggaactgg cacacggcgg cacgctgttt cttgaaaaga
    21781 ttgaatatct ggcggtggag ttacagtctg ctttgcttca ggttatcaag cagggggtta
    21841 tcacgcgact ggatgcgcgg cgtttaatac caattgatgt caaagtgatt gcaacaacga
    21901 ccgcggacct cgcaatgctg gtggaacaaa atcgttttag tcgccagctg tattacgcgc
    21961 tgcatgcatt tgaaattacc atcccgcctc tgcgtatgcg gcgtggcagc attccggcgc
    22021 tggtgaataa caaattacgc agtcttgaaa aacgcttctc tacgcggctg aaaattgatg
    22081 acgatgccct cgctcgcctg gtttcttgtg catggccagg caacgatttt gaactttaca
    22141 gcgtcatcga gaatcttgct ctgagtagtg ataacgggcg cattcgcgtc agtgatttgc
    22201 cggaacatct gtttaccgag caggcgacag atgatgtcag cgccacccgc ctttccacca
    22261 gtctgtcatt tgcggaagtt gaaaaagagg caattattaa cgcagcccag gtcacaggcg
    22321 gtcgcattca ggaaatgtcg gctttacttg ggatcggccg cactacgctg tggcggaaaa
    22381 tgaagcaaca tggcattgat gcagggcagt ttaagcgccg ggtatgaaag acagaaacga
    22441 tttctgatac atcagagtga tctgtatttc attccggcgc acgctaacaa ttttcagcat
    22501 cgtttaaggg cttgtctatc ccgcacttaa aagctgaagc gatatcctcc gttgacttgc
    22561 ttctgatcaa agaggttacc ctgcgtgtaa tccgcttcga gatagaatgt gtgctgtttg
    22621 ttatactgtg cactgactcc cacgccgtta ttccagccat tacctttgaa actgtacttc
    22681 tcccgggagt tgttcaacag atattcggta tcccctgaaa actcgcggat agcgccagtc
    22741 ttcacataga cattcagctg gctgttgcct gcggtgatgt cataccccag tatcatgctg
    22801 gcacgcccca gcagcgattc gtagtgattc agatgtatat tgaggccatt actcgccttc
    22861 atagtcatct cattctggtg gctgtatgta agctgggttt gcggctctat atagaaccca
    22921 taaccagtag gggacaggtt gaacctctgc ccggcttcca gggagatgct cattccattc
    22981 gcagtgccgt tggcgttaac gccgttgttc tgactgtcca gtacgtggaa actatttttc
    23041 tggcgcgatg cttttataac gagatcgctg taaaaaccgt tttgtgccat gtaactggcg
    23101 tacattccca tgtagtctga acgtgcggta ccgtcgcctc cgctatagtc cggcgatgca
    23161 tgtgttgagc caatatacag accgacatac aacggcatta catcagagag acgtttatcc
    23221 ccaccaaact ggataccgct gtaacccatg tcaaagccgc tcagtttgcc actggcaaag
    23281 gagtccaggc ttcccccata actgcgcaac cagatattac cgtctttact ctgatttcgc
    23341 aggtcaccca tccgttgcat cagcgtacgg ttttcaacat agttcaataa gtaaccgaca
    23401 ttgagataat tgccgccagc atctgcggtc gtggtgggtt taggcgtggg agcgggttca
    23461 ggcgtaggat cggggttgac tatgggaggc tgagcgggag ctggtgtggg ttcaggatta
    23521 ggagtcggtt ccggaactgt cccggaagcg taaagctccc agttagtgcc atttttacgc
    23581 acatcgtaca gatatccccc caactcaacc tgagaagacg cgctgaacga ggccgcgccg
    23641 tcagtggttt ttaccactgt cagaacttca tttcccgttg tggcctcgct gccctggttg
    23701 cggatagcca atacgtgatt accagcacta ctcccgctga tattcaataa atccccttta
    23761 ttattaacgc cattaccctc gccaacaaca tcagcacgca taataaaggt actgttaccg
    23821 ctcaggttct ctacgtttaa tgtggcaaat gtgccggcag ttgacccgtg gctggcaaaa
    23881 tcgacagttg aatggctcag cgccagcgtg tcgagattag aattacttgt tacgttccag
    23941 acgctgttat tcattgcaac gtccagtttt ccgccattga cattatcgct gagggaggaa
    24001 cctgtccaaa ccgacccagg gtgcatatcc agattgatta gcccaccttt ggaaagaacg
    24061 ctaccgttga taagcatacg acccgaggcg ttgatgcggc tggcggcata accatcgtca
    24121 tgttgcgttg cgatggccat ctggtcgggt gtactcatat caatgaccag atcgctcgtg
    24181 aggtcgatct ggctgttggt catggcataa attcccctgg ctcctgccgc gccggtgata
    24241 gccaaactgt ctccggttat tctaccgccg ctgagagccc acaaacccag cgccagactg
    24301 ccattacgat caactgtaat atcggtattt tgcatgttga caacagccgt tgccgtctgg
    24361 gccgaggcac cataagaacc gccggaaaag atgctgtttc gttgcgctgc cgtgccagta
    24421 aaattgatta tcgcgtctga accactggtg acgaggccac cgccctgcgc ggaagaaata
    24481 tggctatctg caccgatagt ggttgtacca ccacgaactt cgacgccatt ggccgcggct
    24541 ccagttacat caacagtgag tgcattcgcg ctaacctggc caaagctcca gaggccgtga
    24601 gcattatcgc cattggtttt aatggtactg tttgttccga gatcgacaac agagtttttc
    24661 tgtacgttta tccccatggc gctgtagccc tgaacatcga ttgtcaggtc tgtagccgta
    24721 aaacgcgcag caccattggc gttattgccg ttgagaccac cgatataaac acctgtactt
    24781 ccatcggtcg tgattttact tccgcttcca agatcgacac tggtgccata gtcattgatg
    24841 gttaggccta taccgttcga gttttcaatg gtgaattgag tggctgttag tgttgagcta
    24901 tgcccaataa tgatgccgtc atcgttactc ttaatggtgc tgcctgtgcc taagtcagca
    24961 tgggtatagt caccaattaa gttaatgccg atggcagagg tttgaccaac aacatctact
    25021 gtgagtcggt tagctgtcag ggagctgttt ttgccctgaa taatgattcc ttttgcatat
    25081 ccagaggcgt cgttgacatt gacggtgaca tcattaccca ggttgatatt gccaggcgtg
    25141 tttcctgctg gggtcattac accatagagg tttcctgatg gatcggcggt atctcctgta
    25201 attctgtcac catcattaat agtaatattg gtgccatatt gacttcctgt atcagcagct
    25261 atcagcaggg gggaaaagat aattgcattc aaaccaatag cgccaaat
//
LOCUS       DAPHKZ010000061        24890 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.061, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000061 DAPHKZ010000000
VERSION     DAPHKZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24890
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.061"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            141..1586
                     /gene="tldD"
                     /locus_tag="RH288_002622"
     CDS             141..1586
                     /gene="tldD"
                     /locus_tag="RH288_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HDV4031668.1"
                     /translation="MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
                     SGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
                     GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQ
                     DKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA"
     gene            complement(1720..2649)
                     /gene="aaeR"
                     /locus_tag="RH288_002623"
     CDS             complement(1720..2649)
                     /gene="aaeR"
                     /locus_tag="RH288_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HDV4031669.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDEL
                     QVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK"
     gene            2832..3035
                     /locus_tag="RH288_002624"
     CDS             2832..3035
                     /locus_tag="RH288_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HDV4031670.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            3043..3975
                     /gene="aaeA"
                     /locus_tag="RH288_002625"
     CDS             3043..3975
                     /gene="aaeA"
                     /locus_tag="RH288_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HDV4031671.1"
                     /translation="MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFS
                     ADVVAIAPDVSGLITQVNVHDNQLVKKGQILFTIDQPRYQKALEEAQADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGS
                     NKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWP
                     AGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG"
     gene            3981..5948
                     /gene="aaeB"
                     /locus_tag="RH288_002626"
     CDS             3981..5948
                     /gene="aaeB"
                     /locus_tag="RH288_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HDV4031672.1"
                     /translation="MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIW
                     AGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
                     IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQ
                     GMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDT
                     PVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATE
                     EEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTS
                     LAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSR
                     DRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEK
                     LRIWQAPPQVTEPVNRLAGMLHKYQHALTDS"
     gene            6040..6312
                     /locus_tag="RH288_002627"
     CDS             6040..6312
                     /locus_tag="RH288_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HDV4031673.1"
                     /translation="MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMN
                     DVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH"
     gene            complement(6368..6631)
                     /gene="yhcN"
                     /locus_tag="RH288_002628"
     CDS             complement(6368..6631)
                     /gene="yhcN"
                     /locus_tag="RH288_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HDV4031674.1"
                     /translation="MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSG
                     VASSPMDMREMLNKKAEEKGATAYQITEARSGDTWHATAELYK"
     gene            complement(6996..7466)
                     /gene="argR"
                     /locus_tag="RH288_002629"
     CDS             complement(6996..7466)
                     /gene="argR"
                     /locus_tag="RH288_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HDV4031675.1"
                     /translation="MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL"
     gene            7901..8839
                     /gene="mdh"
                     /locus_tag="RH288_002630"
     CDS             7901..8839
                     /gene="mdh"
                     /locus_tag="RH288_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HDV4031676.1"
                     /translation="MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK"
     gene            complement(8902..9969)
                     /gene="degS"
                     /locus_tag="RH288_002631"
     CDS             complement(8902..9969)
                     /gene="degS"
                     /locus_tag="RH288_002631"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HDV4031677.1"
                     /translation="MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETP
                     ASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGI
                     DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVV
                     VMRDDKQLTLQVTIQEYPATN"
     gene            complement(10059..11426)
                     /gene="degQ"
                     /locus_tag="RH288_002632"
     CDS             complement(10059..11426)
                     /gene="degQ"
                     /locus_tag="RH288_002632"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HDV4031678.1"
                     /translation="MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAP
                     MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEM
                     SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGI
                     KIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESI
                     YLLMR"
     gene            complement(11580..11978)
                     /locus_tag="RH288_002633"
     CDS             complement(11580..11978)
                     /locus_tag="RH288_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HDV4031679.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKSSSSLLPELSAEANPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRTGAKRD"
     gene            12172..13299
                     /gene="zapE"
                     /locus_tag="RH288_002634"
     CDS             12172..13299
                     /gene="zapE"
                     /locus_tag="RH288_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HDV4031680.1"
                     /translation="MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTP
                     PAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQR
                     LHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
                     KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTL
                     TQAHLWLSPLHDETRAQMDKLWLALAGGKRENSPTLEINHRPLATMGVENQTLAVSFT
                     TLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVS
                     AEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG"
     gene            13518..13946
                     /gene="rplM"
                     /locus_tag="RH288_002635"
     CDS             13518..13946
                     /gene="rplM"
                     /locus_tag="RH288_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDV4031681.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            13962..14354
                     /gene="rpsI"
                     /locus_tag="RH288_002636"
     CDS             13962..14354
                     /gene="rpsI"
                     /locus_tag="RH288_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDV4031682.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            14749..15387
                     /gene="sspA"
                     /locus_tag="RH288_002637"
     CDS             14749..15387
                     /gene="sspA"
                     /locus_tag="RH288_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HDV4031683.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS"
     gene            15393..15890
                     /gene="sspB"
                     /locus_tag="RH288_002638"
     CDS             15393..15890
                     /gene="sspB"
                     /locus_tag="RH288_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HDV4031684.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPME
                     YARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDTSIMNDEEASADNETVMSVIDGDKPDHDDDTHPDDEPPQPPRGGRPA
                     LRVVK"
     gene            complement(15933..17300)
                     /gene="dcuC"
                     /locus_tag="RH288_002639"
     CDS             complement(15933..17300)
                     /gene="dcuC"
                     /locus_tag="RH288_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HDV4031685.1"
                     /translation="MFGIIISVIVLITMGYLILKNYKPQVVLAAAGIFLMMCGVWLGF
                     GGVLDPTKSSGYLIVDIYNEILRMLSNRIAGLGLSIMAVGGYARYMERIGASRAMVSL
                     LSRPLKLIRSPYIILSATYVIGQIMAQFITSASGLGMLLMVTLFPTLVSLGVSRLSAV
                     AVIATTMSIEWGILETNSIFAAQVAGMKIATYFFHYQLPVASCVIISVAISHFFVQRA
                     FDKKDKNINHEQAEQKALDNVPPLYYAILPVMPLILMLGSLFLAHVGLMQSELHLVVV
                     MLLSLTVTMFVEFFRKHNLRETMDDVQAFFDGMGTQFANVVTLVVAGEIFAKGLTTIG
                     TVDAVIRGAEHSGLGGIGVMIIMALVIAICAIVMGSGNAPFMSFASLIPNIAAGLHVP
                     AVVMIMPMHFATTLARAVSPITAVVVVTSGIAGVSPFAVVKRTAIPMAVGFVVNMIAT
                     ITLFY"
     gene            17680..18471
                     /gene="nanR"
                     /locus_tag="RH288_002640"
     CDS             17680..18471
                     /gene="nanR"
                     /locus_tag="RH288_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417693.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HDV4031686.1"
                     /translation="MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMI
                     RRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
                     SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVS
                     YQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK"
     gene            18593..19486
                     /gene="nanA"
                     /locus_tag="RH288_002641"
     CDS             18593..19486
                     /gene="nanA"
                     /locus_tag="RH288_002641"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDV4031687.1"
                     /translation="MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYV
                     GGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGP
                     VDEKYLPELKALAQQLMQERG"
     gene            19595..21085
                     /gene="nanT"
                     /locus_tag="RH288_002642"
     CDS             19595..21085
                     /gene="nanT"
                     /locus_tag="RH288_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HDV4031688.1"
                     /translation="MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLAC
                     GFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILY
                     RGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPT
                     GVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYNPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS"
     gene            21133..21822
                     /locus_tag="RH288_002643"
     CDS             21133..21822
                     /locus_tag="RH288_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDV4031689.1"
                     /translation="MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQ
                     AGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADII
                     AIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
                     ETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQ
                     WYNTAMKKAVL"
     gene            21819..22694
                     /gene="nanK"
                     /locus_tag="RH288_002644"
     CDS             21819..22694
                     /gene="nanK"
                     /locus_tag="RH288_002644"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HDV4031690.1"
                     /translation="MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDA
                     LSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIA
                     INDAQAAAWAEFQALDGDITDMVFITVSTGVGGGVVSGCKLLTGPGGLAGHIGHTLAD
                     PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADAKTIFTRAGQGDEQAQQLIHRSA
                     RTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHD
                     AGLLGAALLAQGEKL"
     gene            22691..23155
                     /locus_tag="RH288_002645"
     CDS             22691..23155
                     /locus_tag="RH288_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDV4031691.1"
                     /translation="MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMTFNTQSPVEKKAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQ
                     LCSTIDNEQAIILKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA"
     gene            complement(23215..24342)
                     /locus_tag="RH288_002646"
     CDS             complement(23215..24342)
                     /locus_tag="RH288_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HDV4031692.1"
                     /translation="MESLSEGTTAGYQQIHDGIIHLVDSARTETVRSVNALMTATYQE
                     IGRRIVEFEQGGEARAAYGAQLIKRLSKDLCLRYKRGFSAKNLRQMRLFYLFFQHVEI
                     RQTMSGELTPLGIPQTPSAEFPSAKIWQTLSAKSFPLPRSTYVRLLSVKNADARSFYE
                     KETLRCGWSVRQLERQIATQFYERTLLSHDKSAMLQQHAPAETHILPQQAIRDPFVLE
                     FLELKDEYSESDFEEALINHLMDFMLELGDDFAFVGRQRRLRIDDNWFRVDLLFFHRR
                     LRCLLIVDLKVGKFSYSDAGQMNMYLNYAKEHWTLPDENPPIGLVLCAEKGAGEAHYA
                     LAGLPNTVLASEYKMQLPDEKRLADELVRTQAVLEEGYRRR"
     gene            complement(24527..>24890)
                     /locus_tag="RH288_002647"
     CDS             complement(24527..>24890)
                     /locus_tag="RH288_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031693.1"
                     /translation="TTRLFGLGKTKDNKNIGSYAVLIDSNNISASNGSQTLAVSIAGA
                     DAVITGQKRAWQTLTAYPLAVDQSYYYTFVKPGETTPTPVTNAIIPLQVSASIANDLG
                     GSEKIELDGKAVISVVYL"
BASE COUNT         5973 a         6174 c         6522 g         6221 t
ORIGIN      
        1 cagccgttgc ctgatgcgac gctgtgcgtc ttatcaggcc tacaaaccgg aacataaccg
       61 taggctggat agggcgttca cgccgcatcc ggcagccgta aaaaatcctc tactgcagta
      121 actaacgagt agcaaaaacg atgagtctta acctggtaag tgaacaattg ctagcggcga
      181 acggcctgaa acatcaggac ttgttcgcga tcctcggtca actggccgaa cgtcgccttg
      241 attatggcga tctctatttt cagtcgagct atcacgaatc ctgggtttta gaagaccgca
      301 ttattaaaga tggttcttac aacatcgatc agggcgttgg tgtgcgtgca atcagcggtg
      361 aaaaaaccgg atttgcttac gctgaccaaa tcagcctgct ggcgctggaa cagagtgcgc
      421 aagcggcgcg caccatcgtc cgtgatagtg gtgatggtaa agtacagacg ctgggcgcgg
      481 tagagcatag cccgttgtat acctcggtag atccgctgca aagcatgagc cgtgaagaga
      541 agctggatat cctgcgtcgc gtcgataagg ttgcccgcga agcggacaag cgcgtacagg
      601 aagtgactgc cagcctcagt ggtgtctatg aattaatttt ggttgcggcc accgacggca
      661 cgctagcggc ggatgtccgt ccgctggtgc gtctttccgt gagcgttctc gtcgaagaag
      721 atggcaaacg cgaacgcggt gccagtggcg gcggcggtcg ttttggttat gaattcttcc
      781 ttgccgatct cgacggcgaa gtccgtgcgg atgcatgggc aaaagaagca gtgcgtatgg
      841 cgctggtcaa tctttctgcc gttgctgcac cagcgggcac catgccggta gtacttggcg
      901 caggttggcc gggcgtgctg ttgcatgaag cggttggtca cggtctggaa ggcgacttca
      961 accgccgtgg cacttcagta tttagtggac aggtcgggga gctggtggct tcagaactgt
     1021 gtaccgtggt tgatgatggc acgatggtcg atcgccgagg ttcggtggcg attgatgacg
     1081 aaggtacgcc aggccagtac aacgtgctga ttgagaacgg cattctgaaa ggctacatgc
     1141 aggataaact caacgcgcgt ttgatgggga tgacgccgac tggcaacggt cgccgtgaat
     1201 cctacgccca tctgcccatg ccgcgtatga ccaacaccta tatgctgccg ggtaaatcga
     1261 ccccgcagga aattattgaa tccgttgagt acggtatcta tgcaccgaac tttggtggcg
     1321 gtcaggtgga tatcacctcc ggcaaattcg ttttctccac ttcagaagca tatctgattg
     1381 aaaacggtaa agtaacgaag ccggtgaaag gcgcaacgtt gattggttcc ggtatcgaaa
     1441 ccatgcagca gatttcgatg gttggcaacg acctgaaact ggataacggc gtgggtgtct
     1501 gcggtaaaga agggcaaagt ttgccggttg gcgtgggcca gccaacgttg aaagtcgata
     1561 acctgactgt tggcggtact gcgtaataat ttcactattt tcagaaggat aattaatctt
     1621 tctacgtgca cgaacggtcc cctcgcccct ttggggtgag ggttagggtg aggggaaccc
     1681 gttggcacag gtttgtacaa cgtaacagta caatatgaat tacttctctt tcccgcgccc
     1741 gtgcatctcc tgaaacaatt taccgacctc aacaaaataa tccgtcagcg agttgatcac
     1801 gacctgtacc ttcagcggca gcttatcttt ttcggtatat aacgcataaa ccgggcgtgg
     1861 atctgactgg taacgcggca gcaggatctc cagctcccca cgattgatct cgttgatcac
     1921 ccacatcagc ggcacgtagg cgatcccggc acccgccgtc agccagcgca ccagcgtcat
     1981 cggatcatta gtcacaaatc ttccttgtgg gatcaggcga gtcgagatcc cttccggtgc
     2041 gatcagttca aattcattgt cgggccgcac gctgtattca agccatgaat gactactcaa
     2101 atcggcgggt ttttccggta tgccgtattg tgtgagatag cttttcgcgg cgcacaccac
     2161 cattggcatc gcgcccagac ggcgggaaaa caggctggaa tcctgcaacg cgccgacgcg
     2221 gatcaccaca tccagaccgt cggcaatcag gtcgggggct ggaattccgg taaccagatt
     2281 gacgctcaaa cctgggtatt ctttcagcat tttggctgtc agcccggcga gaacattttg
     2341 tgccatagtt gaagaacagc caatgcgtag cgtcccgatg ggggtgttat tgaaggcata
     2401 cagttgctca tgaacatcct gcacttcatg aagcatacga cggcagccct ggtagtaaat
     2461 tctaccggct tcggtcaggc caatgctgcg tgtgctacgg tttaacagct ttacctgcaa
     2521 ctcatcttcc agttttgata ccgtctgact gatggacgaa acgctcatct gtagctgtct
     2581 ggcggcggcg gtaaaagagc caaattcaac tactttggca aacaccgaca tgcgttttag
     2641 tcgttccatt attcactctg acttaaaagt gatttagatc acataatata gataacagca
     2701 taacagttac gctaatatat taaatatcaa tctacagcaa tgttgctctc gcccggcttt
     2761 ccatgccctt ctctgcggcg acagatgctg aaaataataa cgcctgctct ctctttacaa
     2821 ccaaggtcaa catgagtctg tttcccgtta tcgtggtgtt tgggctgtct ttcccaccga
     2881 tattttttga attgctttta tcactggcga ttttctggct ggtgcgccgg gtacttgtgc
     2941 caacaggtat ctacgacttt gtctggcatc cggcgttgtt caacaccgcg ctctattgct
     3001 gcttgtttta tttgatatcg cgactgttcg tttgaggttg aagtgaaaac actaataaga
     3061 aaattctccc gtacggccat cacggtcgta ttagtcattc tggccttcat cgcaattttt
     3121 aatgcctggg tctattacac cgaatccccc tggacgcgtg acgcgcgctt tagcgctgac
     3181 gtcgttgcga tcgcgccgga cgtttctgga ctcattaccc aggtgaatgt tcatgataac
     3241 cagctggtga aaaaaggaca gatactgttc accatcgacc agccgcgcta tcaaaaggcg
     3301 cttgaggaag cgcaagccga tgttgcttat tatcaggtac tggcacagga gaaacgccag
     3361 gaggccggac gtcgtaaccg tctcggtgtg caggcgatgt ctcgcgaaga gatcgaccag
     3421 gccaacaacg tactacaaac ggttctgcat cagttagcga aagcgcaggc gacccgcgat
     3481 ctggcaaaac tggatcttga acgcacggtg atccgcgcgc cagcagatgg ctgggtgacc
     3541 aacctcaacg tctataccgg tgagtttatt actcgaggat caacggcggt tgcgctggtg
     3601 aaacagaact ccttctatgt actggcctat atggaagaaa ctaagctgga aggggtgcgt
     3661 ccggggtatc gtgcagagat cacgccgctt ggcagtaaca aagtgctgaa agggactgtt
     3721 gatagtgttg ccgcaggggt caccaacgcc agcagcacgc gtgacgacaa agggatggcg
     3781 actatagact ctaaccttga atgggtgcgt cttgcgcaac gtgttccggt tcgtattcgt
     3841 ctcgacaacc agcaagagaa catctggcct gcgggcacca ctgctacagt ggtggtcact
     3901 ggcaaacaag atcgcgacga aagccaggat tcgttcttcc gtaaaatggc ccatcgcctg
     3961 cgtgagtttg gttaatcacg atgggtattt tctccattgc taaccaacat attcgctttg
     4021 cggtaaaact ggcgaccgcc attgtactgg cgctgtttgt tggctttcac ttccagctgg
     4081 aaacgccacg ctgggcggta ctgacagcgg cgattgttgc cgccggtccg gcctttgctg
     4141 cgggaggtga accgtattct ggcgctattc gctatcgtgg ctttttgcgc atcatcggca
     4201 catttattgg ctgtattgcc ggactggtga tcatcattgc gatgatccgc gcaccattat
     4261 tgatgattct ggtgtgctgt atctgggccg gtttttgtac ctggatatcc tcgctggtac
     4321 gaatagaaaa ctcgtatgcg tgggggctgg ccggttatac cgcgctgatc attgtgatca
     4381 ccattcagcc ggaaccattg cttacgccgc agtttgccgt cgaacgttgt agcgagatcg
     4441 ttatcggtat tgtgtgtgcg attatggcgg atttgctctt ttctccgcga tcgatcaaac
     4501 aagaagtgga tcgagagctg gaaagtttgc tggtcgcgca atatcaatta atgcaactct
     4561 gtatcaagca tggcgatggt gaagttgtcg ataaagcctg gggcgacctg gtgcgacgca
     4621 ccacggcgct acaaggcatg cgcagcaacc tgaatatgga atcttcccgc tgggcgcggg
     4681 ccaatcgacg tttaaaagcg atcaatacgc tatcgctgac gctgattacc caatcctgcg
     4741 aaacttatct tattcagaat acgcgcccgg aattgatcac tgatactttc cgcgaatttt
     4801 ttgacacgcc ggtagaaacc gcgcaggacg tccacaagca gctcaaacgc ctgcggagag
     4861 ttatcgcctg gaccggggaa cgggaaacgc ctgtcaccat ttatagctgg gtcgcggcgg
     4921 caacgcgtta tcagcttctc aagcgcggcg ttatcagtaa cacaaaaatc aacgccaccg
     4981 aagaagagat cctgcaaggc gaaccggaag taaaagtaga gtcagccgaa cgtcatcatg
     5041 caatggttaa cttctggcga accacacttt cctgcattct gggcacgctt ttctggctgt
     5101 ggacgggctg gacttccggc agtggtgcaa tggtgatgat tgcggtagtg acgtcactgg
     5161 caatgcgttt gccgaatcca cgcatggtgg cgatcgactt tatctacggg acgctggccg
     5221 cgctgccgtt agggctgctc tactttttgg tgattatccc taatacccaa cagagcatgt
     5281 tgctgctgtg cattagcctg gcagtgctgg gattcttcct cggtatagaa gtacagaaac
     5341 ggcgactggg ctcgatgggg gcactggcca gcaccataaa tattatcgtg ctggataacc
     5401 cgatgacttt ccatttcagt cagtttctcg acagcgcatt agggcaaatc gtcggctgtg
     5461 tgctcgcgtt caccgttatt ttgctggtgc gggataaatc gcgcgacagg accggacgtg
     5521 tactgcttaa tcagtttgtt tctgccgctg tttccgcgat gactaccaat gtggcacgtc
     5581 gtaaagagaa ccacctcccg gcactttatc agcagctgtt tttgctgatg aataagttcc
     5641 caggggattt gccgaaattt cgcctggcgc tgacgatgat tatcgcgcac cagcgcctgc
     5701 gtgatgcacc gatcccggtt aacgaggatt tatcggcgtt tcaccgacaa atgcgccgca
     5761 cagcagacca tgtgatatct gcccgtagcg atgataaacg tcgtcggtac tttggccagt
     5821 tgctggaaga actggaaatc taccaggaaa agctacgcat ctggcaagcg ccaccgcagg
     5881 tgacggaacc ggtaaatcgg ctggcgggga tgctccataa gtatcaacat gcgttgaccg
     5941 atagttaagt caaaaccgac gccaaaagcg tcggtttttt catggctata cttagcgatg
     6001 cacggcagaa ctcgccgcga aacgtgacgg tggcaacaga tgaatattta tacctttgat
     6061 tttgatgaga ttgagagtca ggaggatttt tatcgtgact ttagccaaac ctttggtctg
     6121 gcgaaagata aggtacgcga tctcgactca ctatgggatg tgttaatgaa cgatgtcctg
     6181 ccgctaccac ttgagattga atttgttcat ctgggagaga aaacgcgtcg ccgttttggc
     6241 gcgttaatat tgctgtttga tgaggcagag gaagagctgg aagggcattt gcgttttaat
     6301 gttcgtcatt agcgcaaaaa aaagcccccg aaccgggggc aatatcgtcg gacaagacga
     6361 tgagggttta tttgtacagt tcagccgtag cgtgccaggt gtcaccgcta cgagcttcag
     6421 taatctggta ggccgttgcg cctttctctt ccgctttttt gttcagcatt tcacgcatat
     6481 ccattggcga agacgccaca ccacttacgg atacggtccc gattgcttca cgattttgtg
     6541 cttgtgcagc atcaatggag tcggcagcga atgcaccgaa agagagaaca gaaagtacgc
     6601 ttaatgcagc aacagtggtt ttgattttca tgatttttac ctcgacataa tcttttagct
     6661 gggcctttgt ttcgtgaccc atatcacaaa atcaagtata cactaattat tgagctaatt
     6721 aataccgcgc taactgtttc agttgatact aagtgttaaa aatgtgaatt ttaataacaa
     6781 aaaagaatta aaaatacggt tatttatcgt taattctagt tttttcaatt agataatgaa
     6841 ttttgcataa tgtgcttttt ttaccttatg tattcattgt gtgaatgaca tgtcgcagta
     6901 aaacgcacta ttcgttaaat taatcgcagg ggaaagcagg gggttgagag ggataagcaa
     6961 cattttcccc gccgtcagaa acgacggggc agagattaaa gctcctggtc gaacagctct
     7021 aaaatcgctt cgtacaggtc tttgactgtg aaaccgttag caggggtggt aaagatggtg
     7081 tcatcgccag cgatggtgcc cagaatacct tctgctttgc ccagtgagtc cagcaggcga
     7141 gcaattaact gcgccgcgcc agggctggta tgaatcacga caactgcatc gttgtagtcg
     7201 atatccagca ccagattctt caatggactg gaggtggttg gtacacccag ttcagctggc
     7261 aggcagtaaa ccatttccat tttggcattg cgtgtacgta cagcaccaaa cttggtcaac
     7321 atccgcgaga ctttagactg attaatattg tcaaagcctt gctcctgcaa cgcggcgacg
     7381 atttcgccct gggagctaaa tttctcttct ttaagtaatg ctttaaatgc tttaactagt
     7441 tcttcttgct tagccgagct tcgcataagt cacccgatat ggtggttgat acaacattat
     7501 tgtgcataca gatgaatttt tatgcaaaca gtcagccctg aagaaggctg aaataatgtt
     7561 atgaaagagc gggattttat caaatttcgt tattgagaaa catgcctgcg tcacggcatg
     7621 caaattctgc ttaaaagtaa attaattgtt atcaaattga tgttgttttg gctgaacggt
     7681 agggtatatt gtcaccacct gttggaatgt tgcgctaatg cataagcgac tgttaattac
     7741 gtaagttagg ttcctgatta cggcaattaa atgcataaac gctaaacttg cgtgactaca
     7801 cattcttgag atgtggtcat tgtaaacggc aattttgtgg attaaggtcg cggcagcgga
     7861 gcaacatatc ttagtttatc aatataataa ggagtttagg atgaaagtcg cagtcctcgg
     7921 cgctgctggc ggtattggcc aggcgcttgc actactgtta aaaacccaac tgccttcagg
     7981 ttcagaactc tctctgtatg atatcgctcc agtgactccc ggtgtggctg tcgatctgag
     8041 ccatatccct actgctgtga aaatcaaagg tttttctggt gaagatgcga ctccggcgct
     8101 ggaaggcgca gatgtcgttc ttatctctgc aggcgtagcg cgtaaaccgg gtatggatcg
     8161 ttccgacctg tttaacgtta acgccggcat cgtgaaaaac ctggtacagc aagttgcgaa
     8221 aacctgcccg aaagcgtgca ttggtattat cactaacccg gttaacacca cagttgcaat
     8281 tgctgctgaa gtgctgaaaa aagccggtgt ttatgacaaa aacaaactgt tcggcgttac
     8341 cacgctggat atcattcgtt ccaacacctt tgttgcggaa ctgaaaggca aacagccagg
     8401 cgaagttgaa gtgccggtta ttggcggtca ctctggtgtt accattctgc cgctgctgtc
     8461 acaggttcct ggcgttagtt ttaccgagca ggaagtggct gatctgacca aacgcatcca
     8521 gaacgcgggt actgaagtgg ttgaagcgaa ggccggtggc gggtctgcaa ccctgtctat
     8581 gggccaggca gctgcacgtt ttggtctgtc tctggttcgt gcactgcagg gcgaacaagg
     8641 cgttgtcgaa tgtgcctacg ttgaaggcga cggtcagtac gcccgtttct tctctcaacc
     8701 gctgctgctg ggtaaaaacg gcgtggaaga gcgtaaatct atcggtaccc tgagcgcatt
     8761 tgaacagaac gcgctggaag gtatgctgga tacgctgaag aaagatatcg ccctgggcga
     8821 agagttcgtt aataagtaat tgattagcgg ataataaaaa accggagcac agactccggt
     8881 tttttgtttt gagcgcacga cttaattggt tgccggatat tcctgaatgg tgacctgcag
     8941 cgttaactgc ttatcatcac gcatcactac tacagggatc accgaaccag ggcgaatttc
     9001 cgccacctga tccatcgtct ccagagcaga gatggccggt ttgttatcca ccgaaataat
     9061 cagatcgttg acctgaatac ccgcattcgc cgccgggccg tcaggtgaca cttcattaac
     9121 cacgatccct tgcagttgat ctataccacc gccctgcgcg tgcagtggtg cgatctcacg
     9181 tccgccgata ccaatgtagc cgcggatcac gcgaccatcg cggatcagct tatccataat
     9241 tttggttgct aactggaaag gaatcgcaaa gccgatacct tccggcgttt cgccatcgtt
     9301 actcttatca aacgacagcg tattaatgcc catcagttcg cccagcgagt tcaccagcgc
     9361 gccgccagag ttaccgtggt taatggaagc atcggtttgg aggaagtttt gccgcccggt
     9421 cgggttcaga ccgattcgac ccgtggcact aataatcccc tgggtaatgg tctgcccgag
     9481 gttgtacggg ttaccgatcg ccagtactac gtcgccaatg tgcggtacgc gacgtgcatt
     9541 aattggaatg gtaggtaaac cgccagtggc attaatttta agtaccgcca gatcggttag
     9601 agagtcagat cccaccagca atgcttcaaa tacacgtcca tcctgtaagg cgacgatgat
     9661 ctgatcggcg tcgttgatga cgtgtttatt ggtgatgata taaccgcgtt gatccatgat
     9721 tacaccggat cccagggtgc ggatctcaag ctggttgtga gagttggtgt tcaaaccacg
     9781 gttgtaaacg ttaaccaccg ctggcgcggc gcggcgaacc gccagattat agctggcagg
     9841 cgtctcatcg gtactgtcaa attgcggagt ggaaagcggg ttaaggctgc gcagcgaagg
     9901 catggcaacc agcagaatag cgccgacaat taatccaatc gcaacggaac gtaagagctt
     9961 cacaaacatg atggaggcgt cattaaaaaa gggaacggca gcagcatacc acgagttaac
    10021 cggacatcac acgtaagcct gatgcccggt ttacgacatt aacgcatcag cagatagatg
    10081 ctttcattgc cgcgtacaat ttgcagggcg atgatggccg gttttgccgc cagcacttta
    10141 cgcatttcag caatcgagtt cacccgatcg cggttgacgc caatgatcac atcgtctttt
    10201 tgcaagccag cctgagcagc tgggcttcct ttgacaactt catcgatttt aatacctttg
    10261 ccgccatctt ttagctgacc atcgctcaac gttgcacctt ccagcgctgg cgtgatcatt
    10321 tcagcgctgg ccgacgaaga ggtgctggta tcgagcgtca cttctacttc cagtggtttg
    10381 ccgttacgca gcaggccaag cttcactttc gtgcccggct cggtggtcgc gatacgagag
    10441 cgcaactcag caaagctatt cagcggtttg ccgttgaggc tggtaataat atcgcccgct
    10501 ttgacgcccg cttttgccga gccagaacct ggcaacactt cgctgacaaa cgcgccacgc
    10561 tgcacgtcaa ggttgaaggc tttggcgata tcggcactca tctcggtgcc tttgatgcct
    10621 aacaaaccgc gtttgatttc accaaagtcg ataagctgct gcgccagtgt tcgcgccata
    10681 ttactgggga tggcaaatcc aatcccgacg ctcccgccgc caggcgcaag gattgcagtg
    10741 ttgatgccaa ttaactcacc gttaaggttt aatagtgcac cgccggagtt accgcggtta
    10801 atggaagcat ctgtctggat aaagttttcc agaccttcaa gattcaaccc gctgcggcct
    10861 aatgcggaaa caatgccaga ggtggcggtt tgcccaaggc caaatgggtt accgaccgct
    10921 acggcaaaat caccgacgcg caatttatcg gagtcggcaa tagcgatttg cgttaatttg
    10981 ctcgggtttt gaatttgtaa cagggcgata tcgctctggt catcgctacc aatcagtttt
    11041 gcatcaaact cgcgcccatc attgagctga atactgattt tctgtgcctg attaatcaca
    11101 tggttgttgg tcagcacata gcctttactg gcgttgatga tgacaccgga gcctaaacct
    11161 tcgaagggtt gtgcaggttg atccggtaaa tcatcaccaa aaaacttttt gaattcttcc
    11221 gggattttct gtccctgact ggccgttcct tccacccgta cgctcaccac tgccggaagc
    11281 actttttcca gcattggagc cagactgggg agaggggcct gatcggcaac ctggcctgga
    11341 atcgacgcga cggcctgaaa tgacgccgag agagttaacc cgacacttaa cgctaatgca
    11401 ctcaacagct gggtttgttt tttcattatt cctgctctcg tacctgaatg ataagaaaag
    11461 agattcaaaa cagtttgatg ttattgaatt ttcagacggc taacaatgag acaccagatt
    11521 aaatgatagt cggggaggga gagaagagga gggcgcaatg gctgcgcccg aaaaataaat
    11581 tagtcgcgct tcgcgccagt acgcagcagg ccggatgcgc cttcagaata gtcgcgaggc
    11641 atctgcaccg gtgcctgatc gttgctggct tcagactctg ccagacgatt acggaacggg
    11701 tttgcttcag cagacagttc cggcagcagg ctgctggagc tttttgccat gtgctgatac
    11761 agctggcgat agtcgtgcgc catggtatcc agtaattccg cgctgcgggc aaagtggcta
    11821 accagctctt cgcgatactc gtccagttca gctttattct tttccagttc gtactgcaac
    11881 gcctgttgct ggcgtagttt acgattacca aaacgcatgg ccacagcacc aataatgatg
    11941 ccgacgacta acccaattag cgcatattcc caggtcatga acatctcccg ttgtcttttg
    12001 tttccgtagg gtgttggctt caggctccat gcctgcggct gattatgcca ctataaccgt
    12061 taattccaca gaagtggaat cccgactgca tatcgcgtag tgtagaacgg cctttttttc
    12121 gtcaaccgtg aacaacggcg caccgattat tcaaggaata acaataagat catgcaaagc
    12181 gttaccccaa catcgcaata cctgaaggcg cttaatgaag gcagccatca acccgacgac
    12241 gttcaaaaag aggccgtcag ccgcctggaa attatttatc aggaactcat caatagcacg
    12301 ccaccagccc ccaggacgag tgggctaatg gcgcgggtcg gtaagctgtg gggtaaacgc
    12361 gaagacacaa agcatacgcc agtgcgtggc ttatatatgt ggggcggtgt aggacgcggg
    12421 aaaacctggc tgatggacct tttctatcaa agcctgccgg gagagcggaa acagcgcctg
    12481 cactttcacc gttttatgct gcgggtgcat gaagagctaa ctgccttaca ggggcagacc
    12541 gatccgctgg aaattattgc cgatcgcttt aaagccgaaa ctgacgtgct ctgttttgac
    12601 gaattttttg tttctgatat taccgatgcc atgctacttg gcggtctgat gaaagccctg
    12661 ttcgctcgcg gtattaccct ggtagcgacg tcaaatattc cgccggatga actttatcga
    12721 aatggcctgc aacgtgcgcg ttttctgcct gcaatcgatg ccattaaaca gcattgtgat
    12781 gtaatgaacg tggacgctgg tgttgattat cgtctgcgta cactcactca ggcgcatctg
    12841 tggctttcgc cacttcacga tgaaacccgg gcgcaaatgg ataaactatg gttggcgctg
    12901 gcggggggga aacgagaaaa ttcaccgacg ttagaaatca accatcggcc attagcaaca
    12961 atgggcgtcg agaaccagac gctggcggtc tcttttacta cgctgtgcgt cgacgcccgc
    13021 agtcagcatg actatattgc gctctcacgt ctctttcata cggtcatgtt gtttgatgta
    13081 ccagttatga cgcggttgat ggagagcgaa gcgcggcgct ttattgcgct ggtggatgag
    13141 ttttacgagc gccatgtcaa attagtggtg agtgcagaag tgccgctgta tgaaatttat
    13201 cagggcgatc ggctgaagtt tgagttccag cgttgcctgt cacgtctgca agagatgcaa
    13261 agcgaagagt atctgaagcg cgagcatttg gcgggttaaa acctgtcaca aatcacaaaa
    13321 aggggtcgat ctttgacccc gacttctcta taatcctgcg accccacgtt acaagaaagt
    13381 ttttttccca aaactttttg tgtgctggca taggctattc gaaggggtag gtttgccgga
    13441 ctttgtcgtg tgaacctcaa caattgaaga cgtttgggtg ttcaccaacg tgtaactatt
    13501 tattgggtaa gcttttaatg aaaactttta cagctaaacc agaaaccgta aaacgcgact
    13561 ggtatgttgt tgacgcgacc ggtaaaactc tgggccgtct ggctactgaa ctggctcgtc
    13621 gcctgcgcgg taagcacaaa gcggaataca ctccgcacgt agataccggt gattacatca
    13681 tcgttctgaa cgctgacaaa gttgctgtaa ccggcaacaa gcgtactgac aaagtgtact
    13741 atcaccacac cggccacatc ggtggtatca aacaagcgac ctttgaagag atgattgctc
    13801 gccgtcctga gcgtgtgatt gaaatcgcgg ttaaaggcat gttgccaaaa ggcccgctgg
    13861 gtcgtgctat gttccgtaaa ctgaaagttt acgcgggtaa cgagcacaac cacgcggcac
    13921 agcaaccgca agttcttgac atctaatcgg gattataggc aatggctgaa aatcaatact
    13981 acggcactgg tcgccgcaaa agttccgcag ctcgcgtttt catcaaaccg ggcaacggta
    14041 aaatcgtaat caaccaacgt tctctggaac agtacttcgg tcgtgaaact gcccgcatgg
    14101 tagttcgtca gccgctggaa ctggtcgaca tggttgagaa actggacctg tacatcaccg
    14161 ttaaaggtgg tggtatctct ggtcaggctg gtgcgatccg tcacggtatc acccgcgctc
    14221 tgatggaata cgacgagtcc ctgcgttctg aactgcgtaa agctggcttc gttactcgtg
    14281 acgctcgtca ggttgaacgt aagaaagtcg gtctgcgtaa agcacgtcgt cgtccgcagt
    14341 tctccaaacg ttaattggct tctgctccgg cagaaaacaa ttttcgaaaa aacccgcttc
    14401 ggcgggtttt tttatagcta aaatctgaat cagcgtaaaa actggaaagt tgctttttgc
    14461 tgccacctga cagacaggta aaacaaaaac cacatcgcca ataagggact aagtcaacta
    14521 tttcagacta aagcgcatct ctttttcccc atttccggca tcgactcacc acaatggtcg
    14581 caaaatctgg taaactatca tccaattttc tgcccaaatg tcgggtattg ctcatttttt
    14641 gtttgatttt cgaacaaaga gagtcgttcc ttattgggta acacaacttc tgactggcca
    14701 cctggtggct ggtagcagta aaaattctga ctatacctgg aggttttcat ggctgtcgct
    14761 gccaacaaac gttcggtaat gacgctgttt tccggtccta ctgacatcta tagccatcag
    14821 gtccgcattg tgctggctga gaaaggtgta agtttcgaga tcgaacacgt ggaaaaggac
    14881 aatccgcctc aggatctgat tgacctcaac ccgaatcaga gcgttccgac cctggtggat
    14941 cgtgagctga ccctgtggga atctcgcatc attatggaat atctggatga gcgtttcccg
    15001 catccgccac tgatgcctgt ttacccggta gctcgcggtg aaagccgtct gtacatgcat
    15061 cgcatcgaaa aagactggta cacgctgatg aacaccatca tcaacggttc agcttctgaa
    15121 gcagatgccg cacgtaagca actgcgcgaa gaactgctgg cgattgcgcc ggtcttcggt
    15181 cagaagccgt acttcctgag cgatgagttc agcctggtcg attgctatct tgctccgctg
    15241 ctgtggcgtc tgccgcaact gggcatcgag ttcagcggcc cgggtgcgaa agagctgaaa
    15301 ggctatatga cccgcgtctt tgagcgtgac tctttccttg cttctttaac tgaagcagaa
    15361 cgtgaaatgc gtctgggccg gagttaatct gtatggattt gtcacagcta acaccacgtc
    15421 gtccctatct gctgcgtgca ttctatgagt ggttgctgga taaccagctc acgccgcacc
    15481 tggtggtgga tgtgacgctc cctggcgtgc aggttcctat ggaatatgcg cgtgacgggc
    15541 aaatcgtact caacattgcg ccgcgtgctg tcggcaatct ggaactggcg aatgatgagg
    15601 tgcgctttaa cgcgcgcttt ggtggcattc cgcgtcaggt ttctgtgccg ctggctgccg
    15661 tgctggctat ctacgcccgt gaaaatggcg caggcacgat gtttgagcct gaagctgcct
    15721 acgatgaaga taccagcatc atgaatgatg aagaggcatc ggcagacaac gaaaccgtta
    15781 tgtcggttat tgatggcgac aagccagatc acgatgatga cactcatcct gacgatgaac
    15841 ctccgcagcc accacgcggt ggtcgaccgg cattacgcgt tgtgaagtaa tacaaaacag
    15901 gcccaggcgg cctgttttgt ctttttaatg acttaataaa atagcgtgat tgtggcaatc
    15961 atattcacca cgaaaccgac tgccatgggg atcgctgtcc gcttcaccac cgcaaaaggc
    16021 gaaacgcctg caattcctga cgtaacgacc accaccgcag taatcggcga aaccgcgcgc
    16081 gctagcgtcg tggcaaaatg catcggcata atcattacaa ccgctggtac atgtagtccg
    16141 gctgcgatat tcggaataag actggcaaat gacataaacg gcgcattgcc agagcccatc
    16201 acaatggcac aaatggcaat gaccagcgcc ataataatca tcacgccaat accgcccaga
    16261 ccagaatgct ccgcccccct gataaccgca tcgacagtgc caatcgtcgt taagcctttc
    16321 gcaaatattt cacccgcgac caccagcgtt accacgttgg caaactgcgt acccatgccg
    16381 tcaaaaaacg cctgcacatc gtccattgtt tcgcgcaagt tatgcttgcg gaagaactca
    16441 acaaacatcg tcacagtcaa actcagtaac atcaccacca ccagatgcag ttctgactgc
    16501 atcagcccga cgtgggcgag gaacagcgag ccgagcatca ggattaacgg catcacaggt
    16561 aaaatggcgt aatagagcgg cgggacatta tcgagagctt tttgctctgc ctgttcgtga
    16621 ttgatatttt tatctttttt gtcaaaagcg cgttgcacga aaaagtggga gatcgccacc
    16681 gagataatga cgcaagaggc gaccggaagc tggtagtgga agaagtatgt ggcaattttc
    16741 attcccgcta cctgggcagc aaaaatggag ttcgtttcca gaatccccca ctcaatggac
    16801 atcgtggttg cgataactgc caccgcagag agacgactta ctcccagact caccagcgtc
    16861 ggaaataagg tgaccatcag caacataccc agaccggagg cgctggtgat aaactgcgcc
    16921 atgatttggc cgatgacgta agttgccgac agaataatat acggcgagcg aatgagtttt
    16981 aacgggcggc ttaacaagct caccatcgcg cgactggccc ctatgcgctc catgtagcgg
    17041 gcataaccgc ccaccgccat aatcgacagc cccaatccgg caatgcggtt ggacagcatg
    17101 cgcaggattt cattataaat atcgacgatc aagtagccgc tgcttttggt gggatcgagt
    17161 acaccaccga accctaacca gacaccgcac atcatcagga agatacctgc ggcagccagc
    17221 accacctgag gtttgtagtt tttcaggatc aaatagccca tcgtaattaa tacgatgaca
    17281 gatataatta tgccgaacat tgttgaactc cgtgtcaaaa gaaaacggtc aatcccataa
    17341 acggcagatt gaaaacaacg atgttatatt ttttgcaagg ctatttatgg tgcggatgtc
    17401 gtgtttttaa ttgtaggtga ggtgattttt cattaaaaaa tatgcgctta tgattatttt
    17461 gtaagaacac attcataata ttcataatgc tcgtgaatag tcttataaat aattcaaacg
    17521 ggatgttttt atctgcgtta cattaatttt tcgcaatagt taattattcc gttaattatg
    17581 gtaatgatga ggcacaaaga gaaaaccctg ccattttccc ctactttcaa tcctgtgata
    17641 ggatgtcact gatgatgtta atcacactga ccttacagaa tgggccttat gaacgcattt
    17701 gattcgcaaa ccgaagattc ttcacctgca attggtcgca acttgcgtag ccgcccgctg
    17761 gcgcgtaaaa aactctccga aatggtggaa gaagagctgg aacagatgat ccgccgtcgt
    17821 gaatttggcg aaggtgaaca attaccgtct gaacgcgaac tgatggcgtt ctttaacgtc
    17881 gggcgtcctt cggtgcgtga agcgctggca gcgttaaaac gcaaaggtct ggtgcaaata
    17941 aacaacggcg aacgcgctcg cgtctcgcgt ccttctgcgg acactatcat cggtgagctt
    18001 tccggcatgg cgaaagattt cctttctcat cccggtggga ttgcccattt cgaacaatta
    18061 cgtctgttct ttgaatccag tctggtgcgc tatgcggctg aacatgccac cgatgagcaa
    18121 atcgatttgc tggcaaaagc actggaaatc aacagtcagt cgctggataa caacgcggca
    18181 ttcattcgtt cagacgttga tttccaccgc gtgctggcgg agatccccgg taacccaatc
    18241 ttcatggcga tccacgttgc cctgctcgac tggcttattg ccgcacgccc aacggttacc
    18301 gatcaggcac tgcacgaaca taacaacgtt agttatcaac agcatattgc gatcgttgat
    18361 gcgatccgcc gtcatgatcc tgacgaagcc gatcgtgcgt tgcaatcgca tctcaacagc
    18421 gtctctgcta cctggcacgc tttcggtcag accaccaaca aaaagaaata atgccacttt
    18481 agtgaagcag atcgcattat aagctttctg tatggggtgt tgcttaattg atctggtata
    18541 acaggtataa aggtatatcg tttatcagac aagcatcact tcagaggtat ttatggcaac
    18601 gaatttacgt ggcgtaatgg ctgcactcct gactcctttt gaccaacaac aagcactgga
    18661 taaagcgagt ctgcgtcgcc tggttcagtt caatattcag cagggcatcg acggtttata
    18721 cgtgggtggt tcgaccggcg aggcctttgt acaaagcctt tccgagcgtg aacaggtact
    18781 ggaaatcgtc gccgaagagg cgaaaggtaa gattaaactc atcgcccacg tcggttgcgt
    18841 cagcaccgcc gaaagccaac aacttgcggc atcggctaaa cgttatggct tcgatgccgt
    18901 ctccgccgtc acgccgttct actatccttt cagctttgaa gaacactgcg atcactatcg
    18961 ggcaattatt gattcggcgg atggtttgcc gatggtggtg tacaacattc cagccctgag
    19021 tggggtaaaa ctgaccctgg atcagatcaa cacacttgtt acattgcctg gcgtaggtgc
    19081 gctgaaacag acctctggcg atctctatca gatggagcag atccgtcgtg aacatcctga
    19141 tcttgtgctc tataacggtt acgacgaaat cttcgcctct ggtctgctgg cgggcgctga
    19201 tggtggtatc ggcagtacct acaacatcat gggctggcgc tatcagggga tcgttaaggc
    19261 gctgaaagaa ggcgatatcc agaccgcgca gaaactgcaa actgaatgca ataaagtcat
    19321 tgatttactg atcaaaacgg gcgtattccg cggcctgaaa actgtcctcc attatatgga
    19381 tgtcgtttct gtgccgctgt gccgcaaacc gtttggaccg gtagatgaaa aatatctgcc
    19441 agaactgaag gcgctggccc agcagttgat gcaagagcgc gggtgagttg tttcccctcg
    19501 ctcgccccta ccgggtgagg ggaaataaac gcatctgtac cctacaattt tcataccaaa
    19561 gcgtgtgggc atcgcccacc gcgggagact cacaatgagt actacaaccc agaatatccc
    19621 gtggtatcgc catctcaacc gtgcacaatg gcgcgcattt tccgctgcct ggttgggata
    19681 tctgcttgac ggttttgatt tcgttttaat cgccctggta ctcaccgaag tacaaggtga
    19741 attcgggctg acgacggtgc aggcggcaag tctgatctct gcagccttta tctctcgctg
    19801 gttcggcggc ctgatgctcg gcgctatggg tgaccgctac gggcgtcgtc tggcaatggt
    19861 caccagcatc gttctcttct cggccgggac gctggcctgc ggctttgcgc caggttacat
    19921 caccatgttt atcgctcgtc tggtcatcgg catggggatg gcgggtgaat acggttccag
    19981 cgccacctat gtcattgaaa gctggccaaa acatctgcgt aacaaagcca gtggtttttt
    20041 gatttcaggc ttctctgtgg gggccgtcgt tgccgctcag gtctatagcc tggtggttcc
    20101 ggtctggggc tggcgtgcgc tgttctttat cggcattttg ccaatcatct ttgctctctg
    20161 gctgcgtaaa aacatcccgg aagcggaaga ctggaaagag aaacacgcag gtaaagcacc
    20221 agtacgcaca atggtggata ttctctaccg tggtgaacat cgcattgcca atatcgtaat
    20281 gacactggcg gcggctactg cgctgtggtt ctgcttcgcc ggtaacctgc aaaatgccgc
    20341 gatcgtcgct gttcttgggc tgttatgcgc cgcaatcttt atcagcttta tggtgcagag
    20401 tacaggcaaa cgctggccaa cgggcgtaat gctgatggtg gtcgtgttgt ttgctttcct
    20461 ctactcatgg ccgattcagg cgctgctgcc aacgtatctg aaaaccgatc tggcttataa
    20521 cccgcatact gtagccaatg tgctgttctt tagtggcttt ggcgcggcgg tgggatgctg
    20581 cgtaggtggc ttcctcggtg actggctggg aacccgcaaa gcgtacgttt gtagcctgct
    20641 ggcctcgcag ctgctgatta ttccggtatt tgcgattggc ggcgcaaacg tctgggtgct
    20701 cggtctgtta ctgttcttcc agcaaatgct tggacaaggg atcgccggga tcttaccaaa
    20761 actgattggc ggttatttcg ataccgacca gcgtgcagcg ggcctgggct ttacctacaa
    20821 cgttggcgca ttgggcggtg cactggcccc aatcatcggc gcgttgatcg ctcaacgtct
    20881 ggatctgggt actgcgctgg catcgctctc gttcagtctg acgttcgtgg tgatcctgct
    20941 gattgggctg gatatgcctt ctcgcgttca gcgttggttg cgcccggaag cgttgcgtac
    21001 tcatgacgct atcgacggta aaccattcag cggtgccgtg ccgtttggca gcgccaaaaa
    21061 cgatttagtc aaaaccaaaa gttaatcctg ttgcccggtc tatgtaccgg gcctttcgct
    21121 aagggaagat gtatgtcgtt acttgcacaa ctggatcaaa aaatcgctgc taacggtggc
    21181 ctgattgtct cctgccagcc ggttccggac agcccgctcg ataaacccga aatcgtcgcc
    21241 gccatggcat tagcggcaga acaggcgggc gcggttgcca ttcgcattga aggtgtggca
    21301 aatctgcaag ccacgcgtgc ggtggtgagc gtgccgatta ttggaattgt gaaacgcgat
    21361 ctggaggatt ctccggtacg catcacggcc tatattgaag atgttgatgc gctggcgcag
    21421 gcgggcgcgg acattatcgc cattgacggc accgaccgcc cgcgtccggt gcctgttgaa
    21481 acgctgctgg cacgtattca ccatcacggt ttactggcga tgaccgactg ctcaacgccg
    21541 gaagacggcc tggcatgcca aaagctggga gccgaaatta ttggcactac gctttctggc
    21601 tataccacgc ctgaaacgcc agaagagccg gatctggcgc tggtgaaaac gttgagcgac
    21661 gccggatgtc gggtgattgc cgaagggcgt tacaacacgc ctgctcaggc ggcggatgcg
    21721 atgcgccacg gcgcgtgggc ggtgacggtc ggttctgcaa tcacgcgtct tgagcacatt
    21781 tgtcagtggt acaacacagc gatgaaaaag gcggtgctat gaccacactg gcgattgata
    21841 tcggcggtac taaacttgcc gccgcgctga ttggcgctga cgggcagatc cgcgatcgtc
    21901 gtgaacttcc tacgccagcc agccagacac cagaagcctt gcgtgatgcc ttatccgcat
    21961 tagtctctcc gttgcaagct catgcgcagc gggttgccat cgcttcgacc gggataatcc
    22021 gtgacggcag cttgctggcg cttaatccgc ataatcttgg tggattgcta cactttccgt
    22081 tagtcaaaac gctggaacaa cttaccaact tgccgaccat tgccattaac gacgcgcagg
    22141 ccgcagcatg ggcggagttt caggcgctgg atggcgatat aaccgatatg gtctttatca
    22201 ccgtttccac cggcgttggc ggcggtgtag tgagcggctg caaactgctt accggccctg
    22261 gcggtctggc ggggcatatc gggcatacgc ttgccgatcc acacggccca gtctgcggct
    22321 gtggacgcac aggttgcgtg gaagcgattg cttctggtcg cggcattgca gcggcagcgc
    22381 agggggagtt ggctggcgcg gatgcgaaaa ctattttcac gcgcgccggg cagggtgacg
    22441 agcaggcgca gcagctgatt caccgctccg cacgtacgct tgcaaggctg atcgctgata
    22501 ttaaagccac aactgattgc cagtgcgtgg tggtcggtgg cagcgttggt ctggcagaag
    22561 ggtatctggc gctggtggaa acgtatctgg cgcaggagcc agcggcattt catgttgatt
    22621 tactggcggc gcattaccgc catgatgcag gtttacttgg ggctgcgctg ttggcccagg
    22681 gagaaaaatt atgatgatgg gtgaagtaca gtcattaccg tctgctgggt tacatcctgc
    22741 gttacaggac gcgttaacgc tggcattagc tgccagaccg caagaaaaag cgccgggtcg
    22801 ttacgaatta cagggcgaca atatctttat gaatgtcatg acgtttaaca ctcaatcgcc
    22861 cgtcgagaaa aaagcggaat tgcacgagca atacattgat atccagctgt tattaaacgg
    22921 tgaggaacgg attctgtttg gcatggcagg cactgcgcgt cagtgtgaag agttccacca
    22981 tgaggatgat tatcagcttt gcagcaccat tgataacgag caagccatca tcttaaaacc
    23041 gggaatgttc gccgtgttta tgccaggtga accgcataaa ccaggatgcg ttgtcggcga
    23101 gcctggagag attaaaaagg ttgtggtgaa ggttaaggct gatttaatgg cttaaaactt
    23161 agttcgtttt aaagattctg cagacactgt ctgcagaatt cgaaaccgct gaaattaacg
    23221 gcgtctatag ccttcctcta gcaccgcctg tgttcgaacg agttcatctg cgagtcgttt
    23281 ctcatcaggt agttgcatct tatattcgct tgccagaacg gtgttaggca aacctgccag
    23341 agcataatgc gcttctccgg ctcctttctc tgcacagaga accagaccga tgggcggatt
    23401 ttcatccggt agcgtccagt gctctttggc gtagttgaga tacatattca tctgtccggc
    23461 atcgctatag ctgaatttgc ccacttttag atcgacgatt agcaggcagc gtaaacggcg
    23521 gtggaaaaac agcagatcga cacgaaacca gttgtcatca atgcgtaacc ttcgctgccg
    23581 accaacaaag gcaaaatcat ccccaagttc cagcatgaaa tccatcaggt ggttgatcag
    23641 cgcctcctca aaatcggatt ctgaatattc atctttcaat tccagaaatt cgagcacaaa
    23701 gggatcgcgt atcgcctgtt gcggaagaat atgcgtctcg gcaggagcgt gttgttgcag
    23761 catggctgat ttgtcatgtg acagtagtgt ccgctcataa aactgggtcg caatttgccg
    23821 ctctagctgg cgaacagacc agccacagcg gagcgtctct ttttcataaa agctgcgggc
    23881 gtcagcgttt ttaacggaaa gtaaacggac gtaggtggac ctgggcaagg ggaaagattt
    23941 ggcagacagc gtctgccaaa tctttgccga tgggaattct gcagacggtg tctgcggaat
    24001 tcccaatggt gttaattcgc cagacattgt ctggcgaatt tcaacatgtt gaaaaaagag
    24061 gtaaaaaagc ctcatttggc gtaagttttt tgcagagaac ccacgcttat accttagaca
    24121 taaatccttt gatagtcgct tgattagctg cgcaccatac gcagccctgg cctcgccacc
    24181 ttgttcaaat tcgacaattc gtcggccaat ttcctggtac gtcgcggtca ttaacgcgtt
    24241 aacgctacgt accgtttccg tccgggcgct atcgaccaga tgaataatac cgtcgtggat
    24301 ttgctggtag cctgctgtgg ttccttctga gagcgattcc attatctgtc cctttatatg
    24361 gagctaagtt gaataatgga atgagctata ctctgggggg tgagcactga acaattaaga
    24421 acagcgtatt acatttactt tccccaagat atgcgaagag ctttcctgaa acattaaccg
    24481 atcgtataaa acgaatgcct gatagtactc ctgtccggca ttgttatcac aagtagacta
    24541 cgcttatcac agctttccca tcaagttcga ttttttctga accgcctaaa tcattcgcga
    24601 tagatgcgct cacctgaagc ggtataatgg cgttcgttac aggagttggg gttgtttcac
    24661 ctggttttac aaaggtgtaa taatagcttt gatcgactgc aagcggataa gcggtgagcg
    24721 tttgccatgc tcttttttgc cctgttatga cggcatctgc acctgctatt gatacagcta
    24781 acgtctggct accattgctg gcactaatgt tgttgctatc aattaacacg gcataactac
    24841 cgatattttt attatctttt gttttcccta agccgaataa gcgcgttgtc
//
LOCUS       DAPHKZ010000062        24875 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.062, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000062 DAPHKZ010000000
VERSION     DAPHKZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24875
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.062"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            292..1707
                     /gene="gltX"
                     /locus_tag="RH288_002648"
     CDS             292..1707
                     /gene="gltX"
                     /locus_tag="RH288_002648"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDV4031694.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSK
                     ERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALK
                     APVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEI
                     FTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDT
                     RNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVR
                     DKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALDFIAERENQQ"
     gene            complement(1759..2151)
                     /locus_tag="RH288_002649"
     CDS             complement(1759..2151)
                     /locus_tag="RH288_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416898.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HDV4031695.1"
                     /translation="MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGG
                     RARLILVDTQVCEFIQNTPAFHNTPMLMEAEERIAEYAPGARAPAYRQIINAIDNMTD
                     IEQEKVAQFLSREGIRNFLARLDIDESA"
     gene            complement(2153..2512)
                     /locus_tag="RH288_002650"
     CDS             complement(2153..2512)
                     /locus_tag="RH288_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HDV4031696.1"
                     /translation="MFKERMTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKA
                     RLVHVNEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLL
                     REGIIGLLQRLGIRDSK"
     gene            2733..2808
                     /locus_tag="RH288_002651"
     tRNA            2733..2808
                     /locus_tag="RH288_002651"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2766..2768,aa:Ala,seq:ggc)
     gene            2848..2923
                     /locus_tag="RH288_002652"
     tRNA            2848..2923
                     /locus_tag="RH288_002652"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2881..2883,aa:Ala,seq:ggc)
     gene            3132..5321
                     /locus_tag="RH288_002653"
     CDS             3132..5321
                     /locus_tag="RH288_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416896.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HDV4031697.1"
                     /translation="MFVEHNLIKNIKIFTLAFTLTVVLIQLSRFISPLAIIHSSYIFL
                     AWMPLCVMLSILFIFGWRGVVPVLCGMFCTNLWNFHLSFLQTAVMLGSQTFVVLCACA
                     ILRWQLGTRWRYGLTSRYVWQRLFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDA
                     DAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLGKEKRAFTLS
                     WLAALSVLLLLLCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLN
                     YNQNFLQGVETEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLL
                     PNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSICRTLLPLMQENEK
                     LYQLPGSELLLVLSGPETEGRLQHMVNILNSRQIHWNNTGLDMGYGAAWGRFDGNQET
                     LQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYA
                     QPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATH
                     PCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYHISPQAVILEITEEQAFSNAESSM
                     YNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRS
                     ITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLAD"
     gene            complement(5371..6573)
                     /gene="nupC"
                     /locus_tag="RH288_002654"
     CDS             complement(5371..6573)
                     /gene="nupC"
                     /locus_tag="RH288_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HDV4031698.1"
                     /translation="MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     ISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            6909..8147
                     /locus_tag="RH288_002655"
     CDS             6909..8147
                     /locus_tag="RH288_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDV4031699.1"
                     /translation="MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAY
                     LTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWV
                     IVVLVVALNIWLLVGTALGL"
     gene            complement(8288..8614)
                     /locus_tag="RH288_002656"
     CDS             complement(8288..8614)
                     /locus_tag="RH288_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HDV4031700.1"
                     /translation="MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYW
                     DGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGKGR
                     GHGHRH"
     gene            complement(8729..9985)
                     /locus_tag="RH288_002657"
     CDS             complement(8729..9985)
                     /locus_tag="RH288_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HDV4031701.1"
                     /translation="MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQR
                     LPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPG
                     LIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
                     GTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQM
                     EMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVLVLGIGGFILGILGVIGG
                     PVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVA
                     LGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVML
                     PAWLLLAGKPMMMVNRPKQQPPHDNV"
     gene            10189..11154
                     /gene="glk"
                     /locus_tag="RH288_002658"
     CDS             10189..11154
                     /gene="glk"
                     /locus_tag="RH288_002658"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HDV4031702.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     IRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
                     VDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDI
                     TERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASG
                     FRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            11373..11699
                     /locus_tag="RH288_002659"
     CDS             11373..11699
                     /locus_tag="RH288_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-like phosphotransferase enzyme IIB
                     component 1"
                     /protein_id="HDV4031703.1"
                     /translation="MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGAD
                     GIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDVYEITLQDAIKNAAGIIKEIEEM
                     IASEQQ"
     gene            11721..12968
                     /locus_tag="RH288_002660"
     CDS             11721..12968
                     /locus_tag="RH288_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDV4031704.1"
                     /translation="MAIKKRSATVVPGASGAAAAVKNPQASKTSFWGELPQHVMSGIS
                     RMVPTLIMGGVILAFSQLIAYSWLKIPAEIGIMDALNSGKFSGFDLSLLKFAWLSQSF
                     GGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
                     PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITP
                     FGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLP
                     VTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMFLAFMGISEGAIPFA
                     LESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVI
                     TALMVVFLRLMMFRKGKLLIDSL"
     gene            12983..14068
                     /gene="ypdF"
                     /locus_tag="RH288_002661"
     CDS             12983..14068
                     /gene="ypdF"
                     /locus_tag="RH288_002661"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDV4031705.1"
                     /translation="MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISR
                     ESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSW
                     ETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSE
                     REIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQ
                     GYCSDMTRTLLVNGEGVSAESHPLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRV
                     ITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRI
                     EDVVLVTPQGAEVLYAMPKTVLLTGEA"
     gene            14068..15105
                     /gene="ypdE"
                     /locus_tag="RH288_002662"
     CDS             14068..15105
                     /gene="ypdE"
                     /locus_tag="RH288_002662"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDV4031706.1"
                     /translation="MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGS
                     VLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTR
                     EECKIPGLLDGDRQGNDVSAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRV
                     MGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAI
                     VLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWVETVAAEIGVPLQAD
                     MFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMQQLLSALIQRLT
                     RETVVQLTDFR"
     gene            15130..17625
                     /gene="ptsP"
                     /locus_tag="RH288_002663"
     CDS             15130..17625
                     /gene="ptsP"
                     /locus_tag="RH288_002663"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDV4031707.1"
                     /translation="MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEITFINHRQNAKA
                     DAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTQAELTA
                     HPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRAIPASAQDSTRLEHSLA
                     TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIISNMEQ
                     VCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNKLVLEKPTILVAEDLTPSQ
                     FLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCG
                     VLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPG
                     AFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKS
                     IPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQI
                     LWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMT
                     QYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTTAHQRGKWVGICGELGGESRYLPLL
                     LGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEED
                     VRPLLALENIFVDQDFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVG
                     FGVAIPHTKSQWIRHSSISIARLAKPIGWQSEMGEVELVIMLTLGANEGMNHVKVFSQ
                     LARKLVNKNFRQSLFAAQDAQSILTLLETELTF"
     gene            complement(17628..18456)
                     /locus_tag="RH288_002664"
                     /pseudo
     CDS             complement(17628..18456)
                     /locus_tag="RH288_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416883.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(18469..19203)
                     /gene="ypdB"
                     /locus_tag="RH288_002665"
     CDS             complement(18469..19203)
                     /gene="ypdB"
                     /locus_tag="RH288_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator YpdB"
                     /protein_id="HDV4031708.1"
                     /translation="MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQH
                     NRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKP
                     YQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
                     HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYI
                     LRLKDLDFEVPVSRSKVKEFRQLMHL"
     gene            complement(19218..20915)
                     /gene="ypdA"
                     /locus_tag="RH288_002666"
     CDS             complement(19218..20915)
                     /gene="ypdA"
                     /locus_tag="RH288_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     YpdA"
                     /protein_id="HDV4031709.1"
                     /translation="MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKE
                     LLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRY
                     LIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
                     PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLP
                     LFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQ
                     AMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAV
                     GLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTAR
                     QLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNC
                     CIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERV
                     EANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL"
     gene            21291..22529
                     /gene="alaC"
                     /locus_tag="RH288_002667"
     CDS             21291..22529
                     /gene="alaC"
                     /locus_tag="RH288_002667"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HDV4031710.1"
                     /translation="MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEIDPESEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKA
                     MFRADGLLPASSKHIHENAE"
     gene            complement(22594..22665)
                     /gene="ypdK"
                     /locus_tag="RH288_002668"
     CDS             complement(22594..22665)
                     /gene="ypdK"
                     /locus_tag="RH288_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HDV4031711.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(23021..23941)
                     /gene="lpxP"
                     /locus_tag="RH288_002669"
     CDS             complement(23021..23941)
                     /gene="lpxP"
                     /locus_tag="RH288_002669"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311285.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HDV4031712.1"
                     /translation="MFPQCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRI
                     GAMARPFLKRRESIARKNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDS
                     RVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLFITPEMEGYPTDENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPVGESSLYI"
     gene            24294..24536
                     /locus_tag="RH288_002670"
     CDS             24294..24536
                     /locus_tag="RH288_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HDV4031713.1"
                     /translation="MINLWMFLALCIVCVSGYIGQVLNVVSAVSSFFGMVILAALIYY
                     FTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR"
     gene            complement(24613..>24875)
                     /gene="ypdI"
                     /locus_tag="RH288_002671"
     CDS             complement(24613..>24875)
                     /gene="ypdI"
                     /locus_tag="RH288_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="colanic acid biosynthesis lipoprotein YpdI"
                     /protein_id="HDV4031714.1"
                     /translation="ILFSLFLLVSIMACNVFAFSISGGGSERSYKETEKTSAMTTTHS
                     TKLQPSQAILFKMREDAPPLNLTEEMPPPFPTKANYLIHPVR"
BASE COUNT         5967 a         6155 c         6589 g         6164 t
ORIGIN      
        1 agggaggtgc tctcccagct gagctaatca cccccgctgt gtggagtcgc attataggga
       61 gagttcaaaa tgagtcaacg cattttctaa agaaattgtt cgttcgtcgt aaatttaagc
      121 aagatgatcg caaaacagac cgtgttgcgc aatttgtcaa cgaaaacaat aatgcgtaag
      181 gtagaaaccc gaactacatt gaggaatcag gcgggagtga tagaatatcg cccacttaat
      241 ttttccagga tttgccggtt gtcggcatct ttctaaacgt aaggccattt catgaaaatc
      301 aaaactcgct tcgcgccaag cccaacaggc tatctgcacg ttggcggcgc gcgtactgct
      361 ctttactcct ggctttttgc acgtaaccac ggcggtgagt tcgtgctgcg tattgaagac
      421 accgatcttg agcgttccac gccggaagct atcgaagcca ttatggatgg catgaactgg
      481 ctgagcctgg agtgggatga aggtccgtac taccagacca aacgttttga tcgctacaac
      541 gcggtgatcg atcagatgct ggaagagggc actgcttata aatgctattg ctctaaagag
      601 cgcctggaag cgctgcgcga agagcaaatg gcgaaaggtg agaagccgcg ttatgacggt
      661 cgctgccgcc acagccatga gcatcatgct gatgatgaac cgtgtgttgt acgttttgct
      721 aacccgcagg aaggttctgt tgtttttgac gatcagatcc gtggtccgat cgagttcagc
      781 aaccaggaac tggacgatct tattatccgc cgtaccgatg gttccccaac ctataacttc
      841 tgtgtggttg tcgatgactg ggatatggaa atcacccacg ttatccgtgg cgaagaccat
      901 atcaacaaca cgccacgcca gatcaacatt cttaaggccc tgaaagcgcc ggtgccggtt
      961 tacgcgcacg tttctatgat caatggcgat gacggtaaaa aactgtccaa acgtcacggg
     1021 gcagtcagcg taatgcagta tcgtgatgac ggttatttgc cagaagcact gctgaactat
     1081 ctggtgcgtc tgggctggtc ccacggcgat caggaaatct tcactcgtga agagatgatc
     1141 aaatacttca ctttgaatgc cgtcagcaaa tctgccagtg cgttcaacac cgacaagctg
     1201 ctgtggctga accatcacta cattaacgcg ctgccgccgg agtatgttgc tactcactta
     1261 cagtggcaca ttgagcagga aaatatcgat acccgtaacg gcccgcagct ggctgatctg
     1321 gtgaaactgc tgggcgaacg ctgcaagacg ctgaaagaga tggcacagag ctgccgttat
     1381 ttctacgaag attttgctga gttcgatgcc gacgccgcga aaaaacatct gcgtccggta
     1441 gcgcgtcagc cgctggaagt ggttcgtgac aaactggccg cgattactga ctggaccgct
     1501 gaaaacgttc atcacgctat tcaggcgacg gcggatgagc tggaagtggg tatgggtaaa
     1561 gttggtatgc cgctgcgtgt cgccgtaacc ggtgcggggc agtctccagc actggatgtt
     1621 accgttcacg caattggtaa gacccgcagt atcgagcgta tcaacaaagc gctggatttt
     1681 attgctgaac gcgaaaatca gcagtaatta gcgtgtaaaa agataaacgg caggagataa
     1741 tatcctgccg ttttttattt atgctgattc gtcaatatcg agacgggcga ggaaattgcg
     1801 aattccttca cgtgacaaaa attgcgcgac tttttcctgc tcaatgtctg tcatattatc
     1861 tatcgcgttg atgatttgtc gatacgccgg ggcgcgtgct ccaggagcgt attcagcaat
     1921 tctctcttca gcttccatca acattggtgt gttatggaag gctggcgtgt tctgaataaa
     1981 ctcgcaaact tgcgtatcga ccagaataag tctggcacga ccgcctttca cgccgggaaa
     2041 tttttccgtt ttccagcctt tttctctgat ccaacggtta acagtttgtt tagccacacc
     2101 gaggcattca gccagttctt cggtggtcat tttattgcgt aatcttttca tattatttgc
     2161 tatcgcgaat ccctaagcgt tgtaacaatc cgataatccc ttcccgcaga agcaaggatg
     2221 taaactgttt ttgttcaact ggcgtcatct ctttcgccag tgtcaccagc aatacttcaa
     2281 gcggcgcatc accagaaagg gcaggcgctt ctccctgacc ttctggacgt tcagcattgc
     2341 gaatatattc acgaacctgt tcattgacgt gaaccagtcg ggctttgcca ccctggacgc
     2401 caggttttgg tgacgttgtc cagccttcct tgcgtaccca tttattaatg gtctggcggc
     2461 tatagccggt cagtctggca agttcatctg gtgtcatcct ctccttgaac ataacaattc
     2521 cctgaatgta tgtgggtcta ttagtagttc attttataac accactttac aggaaaccgt
     2581 gacatgaata actactgaat gcgagcggtt ttccaaaatt gttcatttgc ctgatttttc
     2641 agcgattgaa actacacgtt gcaatttgcc gttgacacat tcgggcggaa ttcatatgat
     2701 gccgcccgtc aactcgacaa gctttacgtg acggggctat agctcagctg ggagagcgct
     2761 tgcatggcat gcaagaggtc agcggttcga tcccgcttag ctccaccaaa ttttgcaccc
     2821 agcaaacttg gtacgtaaac gcatcgtggg gctatagctc agctgggaga gcgcttgcat
     2881 ggcatgcaag aggtcagcgg ttcgatcccg cttagctcca ccaaatttcc aaccctcgct
     2941 gcaaagcggg ggttttttgt ctctgctttt tgccgctttt gtaatacagt ctacgtccgg
     3001 gttagtgccg cctggtgaaa gcatcattgg atgaaaaatc ggcaacaggc tggccccctg
     3061 tttgcttcgc gatgcgaata aacttattat ttgtgtgcct gaaaaccccg atcagtgaga
     3121 gtagtgtact catgtttgtg gagcataacc tgataaaaaa tatcaagata ttcacactag
     3181 cgtttacgct caccgtggta cttattcagc tatcccgttt tatttcgcca cttgccatta
     3241 tccattccag ttatatcttt ctggcgtgga tgccactgtg cgtaatgctg tcaatcttgt
     3301 ttatctttgg ctggcgcggt gtcgttcccg ttttatgcgg gatgttttgc accaatctgt
     3361 ggaactttca tctctctttt ttacagactg cggtcatgct cggtagccag acgtttgtcg
     3421 tattgtgtgc ctgcgcaata ttacgctggc agctggggac gcgttggcgt tatggattga
     3481 ccagccgata tgtctggcaa cgtctgttct ggcttggttt ggtgacgccg atcggcatca
     3541 aatgcagcat gtatcttgtg gggagcttct ttgatttccc gctaaagata tccacctttt
     3601 tcggcgatgc ggatgccatt ttcacggtcg ttgatttgct aagccttttc accgctgtgc
     3661 tgatttacaa catgcttttc tactatctca ctcgcatgat tgtaagtccc cactttgcgc
     3721 agatattgtg gcgcagggat atcgctccgt cgttgggcaa agagaaacgc gcatttacct
     3781 taagctggct ggcagcgtta agcgtgctgc tacttctgtt gtgcacacct tatgaaaacg
     3841 actttattgc cggttacctg gtacccgttt tcttcatcat ctttaccctc ggggtcggta
     3901 agcttcgcta tccgttttta aatctcacct gggctgtttc aacgctttgc cttctgaatt
     3961 acaaccagaa ctttttgcaa ggggtggaaa ccgaatattc gctggcattt attcttgcgg
     4021 tgctgatttc ctttagcgtt tgcctgctct atatggtgcg catttatcat cgcagtgaat
     4081 ggcttaatcg ccgctggcat ttgcaggcgc tgacagatcc gttaacgctc ctacccaact
     4141 ttcgtgcgtt ggaacaagcg ccggagcaag aggcgggcaa gagtttttgc tgcctgcgca
     4201 ttgataatct tgagtttatg agtcgtcatt acggcttaat gatgcgcgtt cactgtatcc
     4261 gctcaatttg ccgtacgctg ctgccgttga tgcaggaaaa cgaaaagttg tatcaattgc
     4321 cgggtagtga actgctgtta gtgctgagcg ggccggaaac ggaagggcga ctccagcata
     4381 tggttaacat cctgaatagt cggcaaattc actggaacaa taccgggctg gatatgggct
     4441 atggtgctgc ctgggggcgt tttgatggaa atcaggaaac cctgcaaccc ttgttggggc
     4501 agttaagctg gctggcggag caatcctgcg cacatcatca tgtgctggcg ctggatagca
     4561 gagaggagat ggtttccggg cagaccacta aacaggtgct attgctgaat accattcgca
     4621 cggcgttaga tcagggtgat ttgctgctct acgcccagcc aattcgcaac aaagagggtg
     4681 aaggttatga tgagatcctc gcgcgactga aatatgacgg cggcattatg accccggata
     4741 agtttctgcc ccttattgct cagtttaacc ttagcgcgcg ttttgatttg caagtgctgg
     4801 aatccttgtt gaagtggctg gcaacacacc cttgcgacaa aaaaggaccg cgcttttcag
     4861 tcaatttaat gccgctcacg ctgctgcaaa agaatattgc cgggcggatt attcgtctgt
     4921 ttaagcgtta tcacatctcc ccgcaggcgg tcattcttga gatcaccgag gagcaggcgt
     4981 tttctaacgc agaaagcagc atgtacaaca tcgagcagct gcataagttt ggtttccgga
     5041 ttgcgattga tgactttggc accggatatg ccaactacga acggttaaag cgtttgcagg
     5101 ctgatatcat caaaattgat ggcgtctttg tgaaagatat tgtcacgaac acgctggatg
     5161 cgatgattgt gagatcaatt accgatctgg cgaaagcgaa gtcattgagt gtggtcgcgg
     5221 agtttgtcga gacgcaacag cagcaggcgc tattgcataa gctcggggtg caatatctgc
     5281 aagggtattt gattggtcgc ccgcagccat tagctgatta acaggcgtaa aaaaaccggg
     5341 gaattatccc cggctttttt atgtatggtc ttacagcacc agtgctgcga ttgacgcaga
     5401 cagcacactc accagggtag agccgtaaac cagcttcaga ccgaagcgag aaaccacgtt
     5461 accttgctct tcattcaggc ctttaactgc acctgcgata atcccgattg aagagaagtt
     5521 agcgaaggaa accaggaaca cagagatgat gccttcagca cgcggagaga gcgtggaagc
     5581 aattttctgc agatccatca tcgcaacgaa ctcgttggaa accagtttgg tcgccatgat
     5641 actgcccact tgcagtgctt cactggaagg aacacccatc acccatgcaa tcggatagaa
     5701 gatgtagccc aggatgccct ggaaggagat gctgtagcca aaccagccag taacggtggc
     5761 aaacagtgcg ttcagcgcgg cgatcagggc gataaagcca atcagcatcg cggcaacgat
     5821 aatggcaact ttgaaacctg ccagaatgta ttcacccagc atttcgaaga agctctgacc
     5881 ttcgtgcagg ttggacatct ggatgttttc ttcactggca tcaacacggt aaggattgat
     5941 cagcgacagc acgataaagg tgctgaacat gttcagtacc agcgcagcaa cgacgtattt
     6001 cggttccagc atggtcatgt atgcaccaac gatggacatc gacacggtgg acattgccgt
     6061 ggcagccatg gtgtacatac gattacggga gattttgccg aggatatctt tataggcaat
     6121 aaagttttca gactgaccca gaatcaggga gctgacggcg ttaaaggatt ccagtttgcc
     6181 catgccgttg actttggaga gcaggaaacc aattgcgcgg atgatcaccg gcaacacgcg
     6241 aatgtgctgg agaataccga tcagtgcaga gataaagacg attgggcaca gcactttcag
     6301 gaagaagaat gccaggcctt gatcattcat gctaccaaag acgaagttag tcccttcgtt
     6361 ggcaaatccg agcagttttt cgaacatttc ggagaagcct ttcacgaagc ctaaaccaac
     6421 gtcggagttc aggaagaacc acgccagtaa cacttcgata acaagcagtt gaataacata
     6481 acggatacga atttttttgc ggtcgctgct taccagcagt gcgagaatcg caacaacggc
     6541 aagtgccagt acaaaatgaa ggacgcggtc catatttgct ccaaatatga ggcaggttaa
     6601 atttccgtgc acattctatg taacatggtt aaggaaaacg agatctgaca cacactataa
     6661 tgacgtcctg tgacaggctt caaaaatagt gatctgtcat acatttctgc tatgttgtgt
     6721 atggaagctg aaagttatgt aaatgtgcta acattaaaca taaccataac attcaagtca
     6781 tcaatctttt cgtagtcata atcctggtct atcagagaaa tcaccacaat ccatttaaat
     6841 gaatttgata atcattctcg tttggcatag catgaaacat agcaaaggct atgttttaga
     6901 ggcacaagat gacgaactat cgcgttgaga gtagcagcgg acgggcggcg cgcaagatga
     6961 ggctcgcatt aatgggacct gcgttcattg cggcgattgg ttatatcgat cccggtaact
     7021 ttgcgaccaa tattcaggcg ggtgctagct tcggctatca gctactgtgg gttgtcgttt
     7081 gggccaacct gatggcgatg ctgattcaga tcctctctgc caaactaggg attgccaccg
     7141 gtaaaaatct ggcggagcag attcgcgatc actatccgcg tcccgtagtg tggttctatt
     7201 gggttcaggc agaaattatt gcgatggcaa ccgacctggc ggaatttatt ggtgcggcga
     7261 tcggttttaa actcattctt ggtgtttcgt tgttgcaggg cgcggtgctg acggggatcg
     7321 cgactttcct gattttaatg ctgcaacgtc gcgggcaaaa accgctggag aaagtgattg
     7381 gcgggttact gttgtttgtt gccgcggctt acattgtcga gttgattttc tcccagccta
     7441 acctggcgca gctgggtaaa ggaatggtga tcccgagttt acctacttcg gaagcggtct
     7501 tcctggcagc aggcgtgtta ggggcgacga ttatgccgca tgtgatttat ttgcactcct
     7561 cgctcactca gcatttacat ggcggttcgc gtcaacaacg ttattccgcc accaaatggg
     7621 atgtggctat cgccatgact attgccggtt ttgtcaatct ggcgatgatg gctacagctg
     7681 cggcggcgtt ccacttttcc ggtcatactg gtgttgccga tcttgatgag gcttatctga
     7741 cgctgcaacc gctgttaagc cacgctgcgg caacggtctt tggattaagc ctggttgctg
     7801 cggggctgtc ttcaacggtg gtggggacac tggcggggca ggtggtgatg cagggcttca
     7861 ttcgctttca tatcccgctg tgggtgcgtc gtacagtcac catgttgccg tcatttattg
     7921 tcattctgat gggattagat ccgacacgga ttctggttat gagtcaggta ctgttaagtt
     7981 ttggtatcgc tctggcgctg gttccactgc tgattttcac cagtgacagc aagttgatgg
     8041 gcgatctggt gaacagcaaa cgcgtaaaac agacaggctg ggtgattgtg gtgctggtcg
     8101 tggcgctgaa tatctggttg ttggtgggga cggcgctggg attgtagttg aatgagcgtc
     8161 gcatctggca ctattggcgg atgcggcgta aacgccttat ccgccctacg cgttaaagag
     8221 ccggtttgta ggcctgataa gacgcactag cgtcgcatca ggcattgtgc tccattggcg
     8281 gacgcgttta atggcggtgc ccatgacccc ggccttttcc gcgatgatcg tcacgatcgc
     8341 gccagccttc acgatagcca cgctcatacg ctttacgctt atcccagcca cggtggtagc
     8401 cattatcatg acgccaccaa cggtttttgc gccactcata attgcgatgc cagtagtcac
     8461 ggtcgcgcca gtgaccaccg tcccagtaat taccgtaatg atcgcgatcg ccaatttgta
     8521 atttgattga tggcagtagg gtgatttcac ctgcgtttgc tgcaagcggg gtaaatgcca
     8581 tcagggcggc cgccagaaac agtgacctga acattgttat tctccttcac gctcgaagcc
     8641 gtcagcggcc tgttaacgca atattacggg gaggtaaagc cccgtatcat cgccataact
     8701 cttaaatcat aaaggagagc attttttgct aaacgttatc gtggggtggc tgttgcttcg
     8761 gacgattgac catcatcatc ggcttacctg ctaataacag ccatgccgga agcatgacga
     8821 tacagagcag cggtagcaat gtggtattgg gtacaacgac tgccgccata aaaagactta
     8881 accagccatc gcgtgttacc accagcacga tgccgagaat agcgcaagaa acggttattg
     8941 ccgctggtac ggcgggaacg tgctcatgca gcatcaaccc taatgccacg ccgacaaaca
     9001 ctgccgggaa gattcgccca ccgcgaaagc cactggcggc agcaacgacc agggcggcaa
     9061 gtttaattac cgccagcaaa aagtaatcgc tggtgctgaa agcctgattt gccaccatct
     9121 gctgcatctc atccagccct ttaaacagcg aaactggtcc accaataacc cccagaatac
     9181 cgagaataaa tccgccaata cccagcacga gcaccggatt tttcatttga tgcatcatcg
     9241 cgtgcaaccg tggtaagcac catacggcga ccatccctgc tgcgatggca atcgccgcga
     9301 caattgcacc gctgagaata tcggtcattt ccatctgtcc gtaatgagca atgggcagtg
     9361 aaaaatgagg atggaaaaat aatccggtag taagtgcacc agctgctgcc gccattaacg
     9421 gcgcaaagag acgatcccat agcggaactt cactactgcc atttaaggtt tgcgaaaata
     9481 tcaacgccgc cgcaacagga gtgccaaaca gtgcgccgat ggttccggca gaggctaaaa
     9541 tagtccactc cattcggttg acgcgcggta acagacgagc gccaatggca accgcaaggg
     9601 cgatattgac ggtcatgatc ggatgttccg gccccaggct gacgccgcca gcaagaccga
     9661 gaattaatgc tacgataagt ccaggtagcg cagagggcgg aaccggtgcg ccgatcagcg
     9721 gttcacaggc ggggtctggt ccggcatgac cctggctgaa acggataacc aaccccaccg
     9781 caatacccgt tagcgttaat acaccgatga tccagagggg tgaatcctgg gctatcccca
     9841 gagttcccgg cagtcgttgc cagagcaaat tctgtaatac cgaggcgatt ttcatcacca
     9901 caatcagaat aagactggac gcaatcccaa ttgccacggc ggggagcgat aataacaaca
     9961 tggttctggc tcgcggatgg agcatgttct attccttatg cggggtcaga tacttagttt
    10021 gcccagcttg caaaaaggca tcgctgcaat tggtgctgaa acgataaagt aattgtgtga
    10081 cccagatcga tatttacagg gagcctgcct ttccggcgtt gttgttatgc ccccaggtat
    10141 ttacagtgtg agaaagaatt attttgactt tagcggagca gttgaagaat gacaaagtat
    10201 gcattagtcg gtgatgtggg cggcaccaac gcacgtcttg ctctgtgtga tattgccagt
    10261 ggtgaaatct cgcaggctaa gacctattca gggcttgatt accccagcct cgaagcggtc
    10321 attcgcgttt atcttgaaga acataaggtc gaggtgaaag acggctgtat tgccatcgct
    10381 tgcccaatta ccggtgactg ggtggcgatg accaaccata cctgggcgtt ctcaattgcc
    10441 gaaatgaaaa agaatctcgg ttttagccat ctggaaatta ttaacgattt taccgctgta
    10501 tcgatggcga tcccgatgct gaaaaaagag catctgattc agtttggtgg cgcagaaccg
    10561 gtcgaaggta agcctattgc ggtttacggt gccggaacgg ggcttggggt tgcgcatctg
    10621 gtccatgtcg ataagcgttg ggtaagcttg ccaggcgaag gcggtcacgt tgattttgcg
    10681 ccgaatagtg aagaagaggc cattatcctc gaaatattgc gtgcggaaat tggtcatgtt
    10741 tcggcggagc gcgtgctttc tggccctggg ctggtgaatt tgtatcgcgc aattgtgaaa
    10801 gctgacaacc gcctgccaga aaatctcaag ccaaaagata ttaccgaacg cgcgctggct
    10861 gacagctgca ccgattgccg ccgcgcattg tcgctgtttt gcgtcattat gggccgtttt
    10921 ggcggcaatc tggcgctcaa tctcgggaca tttggcggcg tgtttattgc gggcggtatc
    10981 gtgccgcgct tccttgagtt cttcaaagcc tccggtttcc gtgccgcatt tgaagataaa
    11041 gggcgcttta aagaatatgt ccatgatatt ccggtgtatc tcatcgtcca tgacaatccg
    11101 ggccttctcg gttccggtgc acatttacgc cagaccttag gtcacattct gtaaatcctt
    11161 ccttttatat cgggaggtaa ctctcccgat aatcttttaa atcatacagt ttattcaatt
    11221 tttctttgtg tcccctcaca aggtcgacct gcgtcacact tccgtacagc gggattaatt
    11281 ctccagtaaa tgcattattt gtctggtaac ggcgatttgt tttgcacgtt cataatttca
    11341 ctcgtcaact atcactgaac gaggaattaa cgatgagtaa gaaactgatt gccttatgtg
    11401 cctgcccgat gggcctggct cacaccttta tggccgctca ggcgctggaa gaagcggcgg
    11461 tagaagccgg ttatgaagtg aaaattgaaa cccagggcgc ggacggtatc cagaatcgcc
    11521 tgacggcgca ggatatcgcc gaagcgacca tcatcatcca ctccgtggca gttaccccgg
    11581 aagataacga acgtttcgaa tcacgcgacg tttatgaaat cactttgcag gacgcaatta
    11641 aaaacgctgc gggcatcatc aaagaaatcg aagagatgat tgcctctgaa caacagtaat
    11701 attcgacagg gataattgtt atggccatta aaaaacgcag tgcaaccgtt gtgcctggcg
    11761 catccggtgc ggcagcggca gttaagaatc cgcaggcctc taaaaccagc ttctggggtg
    11821 aactcccgca gcatgtgatg tcagggattt cacgcatggt gccgacctta attatgggcg
    11881 gtgtgatcct cgctttcagc cagctgattg cttatagctg gcttaaaatt cctgctgaga
    11941 tcggcatcat ggatgctctt aatagcggga aattctccgg tttcgacctc tccttactta
    12001 aatttgcctg gctgtcgcag tccttcggcg gcgtgttgtt tggttttgcc attccgatgt
    12061 ttgctgcttt tgtggcgaac tctatcggtg gcaaactggc gttcccggct ggttttatcg
    12121 gcgggttgat gtctacccag ccgacgcaac tgctgaactt cgatcccagc actatgcaat
    12181 gggcgacctc ttcgccggtg ccgtccacct tcattggtgc gctgattatt tctatcgttg
    12241 ccggttacct tgtgaagtgg atgaaccaga aaatccagtt accggatttc ctgttagcgt
    12301 tcaaaaccac atttttgctc ccgattcttt ccgccatttt tgtcatgctg gcgatgtact
    12361 acgtcatcac cccctttggt ggctggatca acggcggtat ccgtactgtg ctgactgccg
    12421 caggtgagaa gggcgcgctg atgtacgcaa tggggatcgc cgcggcgaca gcaatcgacc
    12481 ttggtggccc gatcaacaaa gccgcaggtt ttgttgcctt cagctttacc actgaccacg
    12541 tattaccggt caccgctcgt tctatcgcta tcgttattcc gccgattggt ctggggctgg
    12601 cgaccattat cgaccgtcgt ttaaccggca aacgcctgtt caacgctcaa ctttatccgc
    12661 agggtaagac cgccatgttc ctggcgttta tggggatcag tgagggtgcg attccgtttg
    12721 cgctggaaag ccccatcacc gccattccgt cgtatatggt cggcgctatt gtcggctcaa
    12781 ccgccgctgt ctggctgggc gcagtgcaat ggttcccgga gtccgctatc tgggcatggc
    12841 cgctggtcac taacctgggc gtctatatgg cggggatcgc gctgggggca gtcataactg
    12901 cgctgatggt ggtgttcctg cgtctgatga tgttccgtaa aggcaaattg ttaatcgata
    12961 gcctgtaaga aggaaaatcc agatgacatt actcgcttcg ctgcgcgact ggcttaaggc
    13021 gcaacaactg gatgcagtgc ttctctcctc acggcagaac aaacagccgc atctggggat
    13081 ctccaccgga tcaggttatg tggtgattag ccgtgaaagt gcgcacattc tggtggattc
    13141 gcgctattac gttgaggtgg aagcccgtgc gcaaggctac cagctgcatt tgcttgacgc
    13201 gacgaacacg cttaccacta tcgtcaatca aatcattgcc gatgaacagt tgcaaacgct
    13261 cggttttgag ggccagcagg tgagttggga aaccgcgcac cgctggcagt ctgaactcaa
    13321 tgcgaaactg gttagcgcca cgccggatgt gctgcggcaa atcaaaacgc cagaggaggt
    13381 ggagaaaatc cgcctcgcct gtgggattgc tgatcgcggt gcagagcata ttcgccgctt
    13441 tattcaggcg gggatgagcg agcgcgagat agccgctgaa ctggagtggt ttatgcgcca
    13501 gcagggcgca gaaaaagcct cttttgacac cattgtcgcc agtggctggc gtggggcgct
    13561 gccgcacggc aaagccagcg acaagattgt tgcagcgggc gagtttgtca ctctcgattt
    13621 cggtgcgctg tatcagggct actgctctga tatgacgcgc accttgctgg tgaatggcga
    13681 aggggtgagc gccgaatctc acccgctgtt taacgtctat caaattgtcc tgcaggcaca
    13741 gctcgcagca atctccgcga ttcgccccgg cgtgcgctgc cagcaggttg acgatgccgc
    13801 gcgccgggtc attacagaag caggttatgg cgactatttc ggtcataaca ccggtcacgc
    13861 tatcggcatt gaagttcatg aagatccgcg tttttcaccg cgggacacca cgacgctaca
    13921 gccaggcatg ttactgaccg tggagccggg gatttatttg ccagggcaag ggggcgtgcg
    13981 catcgaagat gttgtgctgg ttaccccgca aggcgcagaa gtgctctacg ccatgccgaa
    14041 aacagtgttg ctcacgggag aggcataatg gatttatcgc tattaaaagc gttgagcgag
    14101 gcagatgcga tcgcctcctc ggaacaggaa gtgcggcaga tcctgctgga agaagcggat
    14161 cgcctgcaaa aagaagtgcg atttgatggt ctgggatcgg tgctgatccg cctgaatgaa
    14221 tcgacaggtc cgaaggtgat gatctgtgcg catatggacg aagtgggatt tatggtgcgc
    14281 agcatctccc gcgaaggggc gattgatgtg ctgccggttg gcaacgtacg catggctgcc
    14341 cgccagctgc agccggtgcg catcaccacc cgtgaagagt gcaaaattcc aggcctgctt
    14401 gacggcgacc ggcaggggaa tgacgtcagc gccatgcgcg tggacattgg tgcgcgctcc
    14461 tatgacgaag tgatgcaggc gggaattcgt cccggcgatc gcgtcacgtt tgataccact
    14521 tttcaggttc tccctcacca gcgagtgatg gggaaagcct ttgatgaccg cctcggttgc
    14581 tatctgctgg tgacgttact gcgcgaactg cacgacgccg aactacctgc ggaagtgtgg
    14641 ctggtggcaa gttccagcga agaggtggga ttacgcggcg ggcaaactgc cacccgcgcg
    14701 gtgtcgccgg acgtcgccat tgtgcttgat accgcctgct gggcgaaaaa ctttgattat
    14761 ggcgcggcta accatcgcca gattggtaac gggccgatgc tggtgttaag cgacaagtcg
    14821 ctgattgcgc cgccaaaact taccgcctgg gtcgaaaccg tggcggcaga aattggcgtg
    14881 ccgttgcagg cagatatgtt cagcaacggc ggcacggacg gcggggcggt gcacttaacc
    14941 ggcaccggcg tgcccacagt ggtgatgggg ccagcaaccc gccatggaca ttgcgccgca
    15001 tcgattgccg attgccgcga cattttgcag atgcagcaac ttttatctgc ccttattcaa
    15061 cgtcttacgc gtgagacggt tgttcaactg acggatttca gatgatctcc tgattaaccc
    15121 ggagcggtta tgttaacgat tcaatttctc tgtcctttgc ctaacggtct acatgctcgt
    15181 ccggcgtggg aacttaaaga acagtgcagc cagtggcaaa gcgaaatcac ttttattaac
    15241 catcgccaga acgcaaaggc agatgcgaaa agctcgctgg cgctgattgg caccggcacc
    15301 ctatttaatg acagttgcag cctgaacatt agcggcagcg atgaagagca ggcgcggcgc
    15361 gtgctggaag agtacatcca ggtgcgcttt atcgacagcg acagcgttca gcctacgcag
    15421 gcagaactga cggcgcatcc gctgccgcgt tcattaagcc gccttaaccc ggatttactg
    15481 tacggcaatg tgctggcaag cggcgtcggc gtgggtacgc tgaccctgtt acaaagcgac
    15541 agcctcgaca gttatcgggc aatccccgcc agtgcgcaag attccacccg gctggagcac
    15601 agcctggcaa cgcttgccga gcaactgaac cagcaattgc gtgagcgtga cggcgaaagc
    15661 aaaactatcc tcagcgccca tttgtcgctg attcaggatg atgaatttgc aggcaatatc
    15721 cgtcgcctga tgacagaaca gcatcagggg ctgggggcgg cgatcatcag caatatggag
    15781 caggtttgcg ccaaactttc tgcctctgcc agcgattatc tgcgcgaacg tgttagcgac
    15841 attcgcgata tcagcgaaca gttgctgcat atcacctggc cggaactgaa gccgcgcaac
    15901 aagctggtgc ttgaaaaacc gaccattctg gtggctgaag atttaacccc aagccagttt
    15961 ttgagccttg atttgaaaaa tcttgcgggc atgattctgg agaaaaccgg gcgcacctcg
    16021 catacactga ttctggcccg tgcctcggcg atcccggtac tgagtggctt gccgctggat
    16081 gcgattgccc gttatgccgg gcaacctgca gtgcttgacg cccagtgcgg cgtgctggcg
    16141 attaacccga atgacgcggt gagcggttat tatcaggtcg cgcagacgct ggcggataaa
    16201 cgccaaaaac aacaggcgca ggctgccgcg cagctggcct attcccgtga taacaagcgt
    16261 attgatattg cggcgaatat cggcaccgct ctggaagcgc caggcgcgtt tgccaacggc
    16321 gcggaaggtg tcgggctgtt ccgtaccgaa atgctctata tggatcgcga cagcgcgccg
    16381 gacgagcagg agcaatttga agcctaccag caggtgctac tggcggcggg cgacaagccg
    16441 attatcttcc gcacgatgga catcggcggc gataaaagca ttccttatct gaatattccc
    16501 caggaagaga acccgttcct cggctatcgc gcggtacgta tttacccgga atttgctggc
    16561 ctgttccgca ctcaactgcg ggccattttg cgcgccgcca gtttcggcaa cgcccagttg
    16621 atgatcccga tggttcacag cctcgatcag atcttatggg tgaaaggcga gatccaaaaa
    16681 gcgatcgttg agcttaagcg cgatggcctg cgtcatgcag agacgattac gcttgggatc
    16741 atggtggaag ttccgtcggt gtgctacatc atcgaccact tctgcgatga ggtcgatttc
    16801 ttcagtatcg gctccaacga tatgacccag tatctgtatg cggtcgatcg taataacccg
    16861 cgcgtatcgc cgctatataa cccgattacg ccatcgttcc tgcgcatgtt gcagcaaata
    16921 gttaccactg cgcatcagcg gggcaaatgg gtaggcattt gcggtgaact gggcggtgaa
    16981 agccgttatc tgccgctact gcttgggctg ggcctggatg agctgagtat gagtagcccg
    17041 cgtattccgg cggtgaaaag ccagcttcgt caactggata gcgaggcgtg tcgggaactg
    17101 gcgcgtcagg catgtgaatg ccgcagtgcg caggaaattg aagcgttact caccgccttt
    17161 acgccggaag aagacgttcg cccactgctg gcgctggaga atatctttgt tgatcaggat
    17221 tttagcaata aagagcaggc gatccagttc ctgtgcggca acctcggcgt taacgggcgc
    17281 actgaacatc cgtttgagct ggaagaagat gtctggcagc gggaagagat tgttaccacc
    17341 ggcgttggtt ttggcgtagc gatcccgcac accaaatctc agtggatccg tcattccagt
    17401 atcagcattg cccggctggc gaaaccgatt ggctggcagt cagaaatggg cgaagtcgaa
    17461 ctggtgatca tgctgacgct gggtgctaac gaagggatga atcatgtgaa agtcttctcg
    17521 cagctggcgc gtaaactggt gaataaaaac ttccgccagt cgttgtttgc cgcgcaagat
    17581 gcacaaagta tcctgacgct gctggaaaca gaattaacct tctgacgtta gccctgaaaa
    17641 cgggcgctgt actctcccgg cgtcagacca aactgacgcc ggaaaaccgc aacgctgtgc
    17701 cacttcatga attgacagat gatatttctg caaaatcatc ctcgccttcg ccattcgcac
    17761 ccaacgcaca tactcgataa aacgcatcgt tccatgctga gcaaacagtt ttgacagatg
    17821 attgggcgtg atattaaaaa actgcgccac gctctcgcgg gtgagcggct gggcataatt
    17881 atcctgaacc cagttacaaa tgctgtgata gagaaaatcg ccgcgcggct gcgaattgcc
    17941 cggcggcata ttcaccacgc tacggcaaag atgcagcaaa cttaacacca gcggctgaat
    18001 gatattttgc tccagcggcg aacggctaag atgggtgagg gcggtaagca tcgcttcacc
    18061 ttcaccgcgt tgcaggctgg gaagctggat ctggcgagca ggatgcaaca acgacgtggt
    18121 gcggctatcg taaaacgata acccaagcca ggtcggagcg aacaccaggc ttaacagcat
    18181 caccggtttg ttgttgaccg gtaaattagc cgcgcgcgcc ggaataaaca gcatttctcc
    18241 ttccaccaaa cgttgctgct ttgcttccag cagattgccg tattcgccgc gcagcacgat
    18301 atccagacgg ggaaaatcaa tacataaact gcccaccggc aacgaggcag gctggctggc
    18361 aaaccagacg cgccccagta gttgcgggtt aagcaccagg ccgctgaaca gatcggcgaa
    18421 aaattgttga tcggcgggca agcctggtgc tttcatgaaa gttcccgatt aaagatgcat
    18481 taactggcga aattctttca ctttgctgcg gctgaccggc acttcaaaat ccagatcttt
    18541 cagtcgcaga atgtaggtgt tattaaacca cggttcgatt tcgcgtattt tgttcagatt
    18601 gacacaaaat gagcgatggc agcggaaaaa atgcgacggc ggcagtttgc tgcaaaattc
    18661 ggtaatgttc atcggcatta cgtaggattc acgccgcgta tagacaaagg tcattttctc
    18721 gtgcgcttcg gcgtaataga tatcgttaat tggcgtgacg attattcgct catctttcac
    18781 cagattaatg gtgtcattct cacgcgttac cgtcgcggca ggcgtactgc tggtctgctg
    18841 ttgttgccag gccgcttcca gtttttgcag catcccggta atacgtgact cctgatacgg
    18901 tttgagaatg tagtcaaacg cctccagttc aaacgcttct accgcatgtt ctttccacgc
    18961 ggtgatgaac acaataaacg gtttatgggc gaactggctg atgttttgcg ccagcaacac
    19021 gccatccagc gacggaatat tgatatccag aaaaatggcg tcgacgcggt tatgctgcaa
    19081 aaacttcaac acgtccagac cgtcgtcaaa ggtgccgaca atctccatct ggctgtgctc
    19141 tttaattagc cagctcagtt cctgttgtgc caggaattcg tcttcaacaa tgatgacttt
    19201 cacaatatca ctccggctca aagcaataac gtagcctgtg aggcgactgg ggtgcgttgg
    19261 ttaggaatgt aaaacgcaat ttccgtcccc ggctccaggc ggcggatatg cagcccctcg
    19321 ccatacaata acttcacgcg atgatggaca ttcagcaggc caattttatt gcccggcatt
    19381 tcattcgctt cgacccgctc aatcaccttt ggatcgatgc cgtgcccggt atctcgcacc
    19441 gcaatgcgta cccgatttcc gcactctgca acgctgatgg tgacaacgcc tttacctttg
    19501 caaggctgaa taccgtggac aatggcgttc tccaccaacg gctggatcag caggctggga
    19561 atgcagcaat tcacctcttc atcaatatca tagataaccg tcagcttgtc accaaagcgg
    19621 gcctgctcaa tggcaatata gtctttaatt tgatacagct cttttttgat atcgatttgc
    19681 tcatcgtctt ttaattcaat gttatagcgc agataacgcg acagattaaa gatcaactgg
    19741 cgagcggtat ccggattcag acggattgac gatgaaatag cgttcagagc gttaaacaga
    19801 aaatggggat taattttgct ttgcagggcg cgaagctctg ccttatttgc catttcacgt
    19861 agctgctcgg cgcgtgaaac ctccagttgc gtggagatga tttgcgacag accgaccgcc
    19921 atttcctgta atgacgaggt gatctgatgc gcgtggcagt agtaaatttt cagcgttccg
    19981 gtcacgaccc ctttctccca caatgggatc accagcatgg aatgaatctc tggtgtgcgg
    20041 tgggcttcat cattgttttt aatgatgatt tttccgtaat tcatcgcctg acgggtagtc
    20101 gggctaatga agtcatcgcc attctgatag ttatgttcac ccacgccaac ataggccagc
    20161 acatgatcgg tattagtaat cgccaccgca tcggcgtgaa tgtcatcgcg gataatttcg
    20221 cagaccttgc gtaatgactc gctattgaca tggcgaaaca gcggtagcgt tttgttggcg
    20281 atatccagcg ccagcttggc ctgccgcgcg gcgctggcct ctttttcgcc ctcaacgctt
    20341 tgcaccagaa gcacaataaa gccgatacag acgctaccga ggatcattgg aatgccgatt
    20401 ttagagacga tatcgatccc caacgcggta gttggtgccc agacaattac cagaatcatg
    20461 gtcaacgtct cacacaacat gccgccgaga ataccgacgc gccagcgctg tgctttgggg
    20521 attttcaggt tgatccagcc cgatatacaa cccgccagaa tgctggtgat aaagcagggg
    20581 atcgccgtca cgccgccgat atcaattaaa taccggtgaa tacccgcaat cacgccggta
    20641 atgatgccta cccacgggcc aaacagaatc ccgccggaca tcaccgcgat aatacgtacg
    20701 ttcaccagcg agccttctac gggaacgccg gaccaggtgc tgaacagggc gaacagcgag
    20761 aaaatggcgg taacggcgag caattctttt ggggagtgcg ccgacttgtg caacagttcg
    20821 cgaaacaggc ggatacggat gagaaagaac aggcagataa gcattaacgc tgcccgatcg
    20881 aagaccgcca gcagcatgtt gaatatttcg tgcacgggtg actctgaata aggattaaac
    20941 ctctatgata ggtaacctga aggctgatga ccagcaggcc gtttttgagg aaaaaccaca
    21001 attttaaaag gggattgata gataaatggt gtattagcaa tgcatctctt gataatgcac
    21061 ttctggttag taaatttatt gaaattatta tgttaataaa atgagtggta attttcttgt
    21121 tagcgcagat aaatttcctg tttttaaagc agagttcctc atttaacgtc attaataaaa
    21181 tgttctaaaa cgctggacag acagaaatta atcaggctat tttcaaaaca gccaccatcg
    21241 tggcagcgtc gctcggacgg tccgggcgct aacgttaatc tgaggaaatt atggctgaca
    21301 ctcgccctga acgtcgcttt acgcgcattg atcgtctccc gccctacgtt tttaacatca
    21361 ccgctgaact gaaaatggct gcgcgtcggc gcggcgaaga tattatcgat ttcagcatgg
    21421 gtaacccgga cggtgcgact ccgccgcata tcgtcgaaaa attatgtact gtggcccagc
    21481 gcccggacac gcatggttac tccacttcac gcggcattcc gcggttacgt cgcgccattt
    21541 cccgctggta tcaggatcgc tacgacgttg aaatcgaccc ggaatcagaa gccatcgtca
    21601 ctattggttc gaaagagggc ctggcgcatc tgatgctggc gacgctggat catggtgaca
    21661 cggtgctggt gccgaatcca agttacccga tccatattta tggcgcggtg attgccgggg
    21721 cgcaggtacg ctcagtgccg ctggtggaag gtgtcgattt cttcaacgaa ctggagcgag
    21781 ccattcgtga aagttatccg aaaccgaaga tgatgatcct cggcttcccg tcaaacccaa
    21841 ccgcgcaatg cgtggaactg gagttcttcg aaaaagtagt ggcgctggcg aaacgctacg
    21901 atgtgctggt ggtccatgac ctggcctatg ccgatatcgt ctacgatggc tggaaagcgc
    21961 cgtcaattat gcaggtaccg ggtgcacgcg atgtggcagt cgagttcttt acgctgtcga
    22021 aaagctacaa catggcgggc tggcgtatcg gctttatggt tggcaacaaa acgctggtca
    22081 gcgccctggc tcgtattaaa agctatcacg attacggcac ctttacgccg ttgcaggtgg
    22141 cggcgattgc ggcgctggag ggcgatcaac agtgcgtgcg cgacattgcc gaacagtaca
    22201 aacgccgccg tgatgtattg gttaaagggc tgcatgaagc gggctggatg gttgaaatgc
    22261 cgaaggcttc gatgtatgtc tgggcgaaaa tcccggaacc atatgcggcc atgggatcgc
    22321 tggaatttgc caagaagctc cttaacgaag cgaaggtttg tgtctcgccg gggattggct
    22381 ttggcgacta tggtgatacg catgttcgct ttgcactgat tgaaaaccgc gaccgtattc
    22441 gtcaggccat cagagggatt aaagcgatgt tccgtgccga cggtttacta cccgccagca
    22501 gcaaacatat tcacgaaaac gcggaataaa caccgtcgtc agaaatgcaa acaggagcct
    22561 gatggctcct gtttttcatt gcacagtttg cttttagatc atcagggcaa aagtaccggc
    22621 ccaaacgatg accataaaag aaatgcccat aaagaaatat ttcactttac atctctccgc
    22681 gtaattactg ttacgcctga atgacttcat tacacctgat acagtgagtt gacaccgggc
    22741 aaagcgacct taaaagccct gtattttacc gtgggcatca ccccagaatt ctgagctaaa
    22801 ctgctcgaga cggcgctaat gtacgcctaa aactgaaacg agacaagagg cattttctta
    22861 tttactttta gtaacttaca agtgtctcat atcggcgaca gtttaatttc tgacggtaat
    22921 aattagatat tcagcgaagg aaaaaacctt aagaaaaaag ccataaaaac catgaggtta
    22981 ttatggccga tttgaggagg gaaagagtaa gagcagtttg ttaaatgtac aacgacgatt
    23041 ctcccaccgg gcgcgtttta aagcgacggt ggatccagag gtactgctcc ggtgcgcgca
    23101 tgatctcttt ctcgataatc ttgttcatat aggcagcggc ttgattttca tctgtcgggt
    23161 agccttccat ctctggggtg atgaacaaac gatatccgct gtaatccgct tttcttacca
    23221 tcgttacggt caacatggct gcgccagaga gacgggagag aacataggtg ccattggttg
    23281 tggcgacatt ttccaccgca aagaacggcg cgaaggagct gcctttacga ccataatcct
    23341 gatcgggagc aaaccatacc gcttcacctt tcttcagtgc accgacaatg ccgcgcagat
    23401 tatttctgcc gatcatcgct ttgttagagc gcatgcgccc acgggtctgc acccattcca
    23461 tcagctgatt attatgtgga cgataggtag ccatcattgg ttggcacagt cccatcacgc
    23521 ggccgcccag ttccagcgac ataaaatgga cgccgacaac cattacgccg cgattttgca
    23581 tttgtgcgcg tttaaggtta tccaaccctt caacatcaaa ccatttacgt acgcgactgt
    23641 cgggccagaa ccatgccatg ccggtttcta ccagcgccat gccgagtgaa cgaaagtttt
    23701 cggcaatcat cttctcgcgt tcttccgcag aatgctgcgg gaaacaaagt tccaggtttt
    23761 tacgggcgat agattcacga cgtttcagga atggtcgcgc cattgcgcca atacgcgtgc
    23821 cgagaaagca gagaacagga taaggaagct gtacccaaag ccagagtaca ccaagcccaa
    23881 accatgtgag ccagtagcga ggatgtagaa actcgcggga aaatttgcat tgtggaaaca
    23941 tagttacctt ctgtagatac gaattgttgt atcgcagaag attccatgtc gacagcggta
    24001 cactcaattg gttgggccat catgtacgac aatggttcct gtaaagagtg taaagactag
    24061 tcaggacata accacgagga gcatgaatgc ggtatctgta ctttatcact cgctgactgc
    24121 tttcagctac tgattattaa tcgtgcaaag taaatatttt tccgtacaca acagtcttgc
    24181 atttaacatg ctgttttcat tgatgcttag caaaaattgc cagaggttaa gaattgtctt
    24241 actattaaag tgactgaagt tacaggtttt ttagcgcggc aggaggttga gctatgatta
    24301 atttatggat gtttctcgcc ctgtgtattg tctgcgtaag cggctacatc ggtcaggtac
    24361 tgaacgtggt atcggcggtc tcttctttct tcggcatggt gatcctcgct gcactcattt
    24421 attacttcac catgtggtta actggcggta atgaactagt gacggggata tttatgtttc
    24481 ttgccccggc ttgtggcttg atgattcgct ttatggtggg gtatggcagg cggtagtggg
    24541 tcaggatggc tcatttgggc aggtgttcac atcagcatca gacatgattg ttcacctgcc
    24601 atgtgaaaga agctatcgca caggatgaat aagataattc gcctttgtcg gaaaaggggg
    24661 cggcatttct tctgtgaggt ttaatggtgg cgcatcttct ctcatcttaa acaaaatcgc
    24721 ctgtgatggc tgaagttttg tagagtgtgt ggtcgtcatc gctgatgttt tttcagtctc
    24781 tttatagctc ctctcacttc caccacccga aatggaaaat gcaaaaacat tgcatgccat
    24841 aatagagacc aataaaaata agctgaaaag tatta
//
LOCUS       DAPHKZ010000063        24663 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.063, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000063 DAPHKZ010000000
VERSION     DAPHKZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24663
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.063"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            346..1152
                     /gene="xthA"
                     /locus_tag="RH288_002672"
     CDS             346..1152
                     /gene="xthA"
                     /locus_tag="RH288_002672"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDV4031715.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKETPIAVRRGFPGDDEEAQRRIIMAEIPSLLGN
                     VTVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRDNPVLIMGDMNISPTDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMDRLMSWGLVDTFRHANPQTADRFSWFDYRSK
                     GFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR"
     gene            1319..2029
                     /locus_tag="RH288_002673"
     CDS             1319..2029
                     /locus_tag="RH288_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416264.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDV4031716.1"
                     /translation="MNAERKFLFACLIFALVIYAIHAFGLFDLLTDLPHLQTLIRQSG
                     FFGYSLYILLFIIATLLLLPGSILVIAGGIVFGPLLGTLLSLIAATLASSCSFLLARW
                     LGRDLLLKYVGHSNTFQAIEKGIARNGIDFLILTRLIPLFPYNIQNYAYGLTTIAFWP
                     YTLISALTTLPGIVIYTVMASDLANEGITLRFILQLCLAGLALFILVQLAKLYARHKH
                     VDLSASRRSPLTHPKNEG"
     gene            2034..2711
                     /gene="ydjY"
                     /locus_tag="RH288_002674"
     CDS             2034..2711
                     /gene="ydjY"
                     /locus_tag="RH288_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416265.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdjY"
                     /protein_id="HDV4031717.1"
                     /translation="MLQHYSVSWKKGLAALCLLAVAGLSGCDQQENAAAKVEYDGLSN
                     SQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKDGSNGHKSLFMGYATPKAFYEAL
                     KEAGGTPGENMTMDNKETTHVTGSKLDISVNWQGAAKAYSFDEVIVDSNGKKLDMRFG
                     GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLAT
                     VTFKIAE"
     gene            2726..3433
                     /locus_tag="RH288_002675"
     CDS             2726..3433
                     /locus_tag="RH288_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDV4031718.1"
                     /translation="MMMMQSRKIWYYRITLIILLFAMLLAWALLPGVHEFINRSVAAF
                     AAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGAFWGGLLS
                     WTSSMAGAALCFFIARVMGREVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLPFVPF
                     DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTV
                     VIFMAKKIWLERQKRNA"
     gene            3433..3981
                     /locus_tag="RH288_002676"
     CDS             3433..3981
                     /locus_tag="RH288_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDV4031719.1"
                     /translation="MGLPPLSKIPLILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLV
                     SMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCVDITSMKVAERTGSSDKLLAVAD
                     WRQSPLFSDEERLALEYAEAASVTPPTVDDALRTRLAAHFDAQALTELTALIGLQNLS
                     ARFNSAMDIPAQGLCRIPEKRS"
     gene            3991..5157
                     /locus_tag="RH288_002677"
     CDS             3991..5157
                     /locus_tag="RH288_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV4031720.1"
                     /translation="MRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDT
                     AINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTEAAAGRKTGGSVDLLWVNGE
                     NFRTLKEANLLQTGWAETLPNWRYVDTQLPVREDFSVPTQGAESPWGGAQLTFIARRD
                     VTPQPPQTPQALLEFAKANPGTVTYPRPPDFTGTAFLEQLLIMLTPDPAALKEAPDDA
                     TFARVTAPLWQYLDVLHPYLWREGKDFPPSPARMDALLKAGTLRLSLTFNPAHAQQKI
                     ASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAAKVVANFLLSPDAQLRKADPAV
                     WGDPSVLDPQKLPDGQRESLQSRMPQDLPPVLAEPHAGWVNALEQEWLHRYGTH"
     gene            5130..6665
                     /locus_tag="RH288_002678"
     CDS             5130..6665
                     /locus_tag="RH288_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416269.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDV4031721.1"
                     /translation="MATPLRYALIFLLWAMVAVIYAPLIPAALTLISPALSLTHWQAL
                     FADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVA
                     FATSALLLFADGGLLYDYFPYFTPPMDRFGIGLGLTLAVKESAFLLWILAAVLSEKWL
                     LQQVIVLDSLGYSRWQCLNWLLLPSVAPALAMAMLAIVAWSLSVVDVAIILGPGNPPT
                     LAVISWQWLTQGDIDQQTKGALASLLLMLLLAAYVLLSYLLWRSWRRTIPRVDGVRKP
                     ATPLLPGNTLAIFLPLTGVLCVVLLAILADQSTINSEALINSLTMGLVATFIALLLLL
                     LWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLKLDGSWTAVVWGHLLWVMPWML
                     FILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPVLIAFAVGFAVGIAQYMP
                     TLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVAKWVGYVRQ
                     GLR"
     gene            6665..7318
                     /locus_tag="RH288_002679"
     CDS             6665..7318
                     /locus_tag="RH288_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDV4031722.1"
                     /translation="MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLF
                     SWMIGALAEQFSCTGELWLNEQRIDILPTAQRQIGILFQDALLFDQFSVGQNLLLALP
                     ATLKGNARRNAVNDALERSGLEGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEP
                     FSRLDVALRDNFRQWVFSEVRALAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR"
     gene            7385..8692
                     /gene="ynjE"
                     /locus_tag="RH288_002680"
     CDS             7385..8692
                     /gene="ynjE"
                     /locus_tag="RH288_002680"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416271.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YnjE"
                     /protein_id="HDV4031723.1"
                     /translation="MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAID
                     TRPSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMSTEQLNAWIKQHNLKTDAPVALY
                     GNDKDVDAVKTRLQKAGLTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
                     TAKPAGDWKVIEAAWGAPKLYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKH
                     GIRHDTTVILYGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKV
                     KAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGE
                     IAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPEQQVSFYCGTGWRAS
                     ETFMYARAMGWKNVSVYDGGWYEWSSDPKNPVATGERGPDSSK"
     gene            complement(8701..9321)
                     /locus_tag="RH288_002681"
     CDS             complement(8701..9321)
                     /locus_tag="RH288_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416272.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDV4031724.1"
                     /translation="MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALP
                     FLALGWYLAALVVILLNRLLDGLDGALARRRELTDAGGFLDISLDFLFYALVPFGFIL
                     AAPEQNALAGGWLLFAFIGTGSSFLAFAALAAKHQIDNPGYAHKSFYYLGGLTEGTET
                     ILLFVLGCLFPAWFAWFAWIFGALCWMTTFTRVWSGYLTLKSLQRQ"
     gene            9408..9815
                     /gene="nudG"
                     /locus_tag="RH288_002682"
     CDS             9408..9815
                     /gene="nudG"
                     /locus_tag="RH288_002682"
                     /EC_number="3.6.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP pyrophosphohydrolase"
                     /protein_id="HDV4031725.1"
                     /translation="MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKVEPDES
                     QRQALVRELREELGIEATVGEYVASHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALV
                     WCSPEEALQYPLAPADIPLLEAFMALRAARPAD"
     gene            complement(9781..10053)
                     /locus_tag="RH288_002683"
     CDS             complement(9781..10053)
                     /locus_tag="RH288_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HDV4031726.1"
                     /translation="MSRALFAVVLAFPLIALANPHYRPDVEVNVPPEVFSSGGQSAQP
                     CTQCCVYQDQNYSEGAVIKAEGILLQCQRDDKTLSTNPLVWRRVKP"
     gene            10289..11632
                     /gene="gdhA"
                     /locus_tag="RH288_002684"
     CDS             10289..11632
                     /gene="gdhA"
                     /locus_tag="RH288_002684"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDV4031727.1"
                     /translation="MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPK
                     YRQMSLLERLVEPERVIQFRVVWVDDRNQIQVNRAWRVQFSSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
                     DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTK
                     EKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSLPVDIALPCATQNELDVDAAHQ
                     LIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLG
                     WKAEKVDARLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLAQGVI"
     gene            complement(11749..12789)
                     /locus_tag="RH288_002685"
     CDS             complement(11749..12789)
                     /locus_tag="RH288_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416276.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HDV4031728.1"
                     /translation="MKKVLLQNHPGSEKYSFNGWEIFNSNFERMIKENKAMLLCKWGF
                     YLTCVVAVMFVFAAITSNGLNERGLITAGCSFLYLLIMMGLIVRAGFKAKKEQLHYYQ
                     AKGIEPLSIEKLQALQLIAPYRFYHKQWSETLEFWPRKPEPGKDTFQYHVLPFDSIDI
                     ISKRRESLEDQWGIEDSESYCALMEHFLSGDHGANTFKANMEEAPEQVIALLNKFAVF
                     PSDYISDCANHSSGKSSAKLIWAAELSWMISISSTAFQNGTIEEELAWHYIMLASRKA
                     HELFESEEDYQKNSQMGFLYWHICCYRRKLTDAELEACYRYDKQFWEHYSKKCRWPIR
                     NVPWGASSVKYS"
     gene            complement(12917..14878)
                     /gene="topB"
                     /locus_tag="RH288_002686"
     CDS             complement(12917..14878)
                     /gene="topB"
                     /locus_tag="RH288_002686"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDV4031729.1"
                     /translation="MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAG
                     DPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIV
                     TSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCR
                     YLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSA
                     INLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELHIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMAT
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGG
                     SADKKKAAPRKRSAKKSPPADEVGSGAIA"
     gene            complement(14883..15926)
                     /gene="selD"
                     /locus_tag="RH288_002687"
     CDS             complement(14883..15926)
                     /gene="selD"
                     /locus_tag="RH288_002687"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDV4031730.1"
                     /translation="MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFAN
                     IEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYEAIPKLPGVEEYIKLGAVPGGTER
                     NFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKATAAEFGIELTAIGEL
                     VPARGGRAMVEIR"
     gene            complement(16043..16594)
                     /locus_tag="RH288_002688"
     CDS             complement(16043..16594)
                     /locus_tag="RH288_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HDV4031731.1"
                     /translation="MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQP
                     WHFFVIEGEGRERFSAVLEQGAIAAGSDDKAIDKARNAPFRAPLIITVVAKCEENHKV
                     PRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
                     GTPQLKASTSINVPDPTPFVTYF"
     gene            16755..18611
                     /gene="sppA"
                     /locus_tag="RH288_002689"
     CDS             16755..18611
                     /gene="sppA"
                     /locus_tag="RH288_002689"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDV4031732.1"
                     /translation="MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQ
                     VSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVN
                     TIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
                     YLASFANKIWLFPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKYA
                     LENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFAN
                     GAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGV
                     HTDGVSTSPLADVSITRALPPEAQQMMQLSIENGYKRFITLVADARHSTPEQIDKIAQ
                     GHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSG
                     SVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANVR"
     gene            18778..19794
                     /gene="ansA"
                     /locus_tag="RH288_002690"
     CDS             18778..19794
                     /gene="ansA"
                     /locus_tag="RH288_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDV4031733.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRP
                     EMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALS
                     FMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIY
                     PGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELHEASDRGIVVVNLTQCMSG
                     KVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQELDTETIRKAMSQNLRGEL
                     TPDD"
     gene            19805..20446
                     /locus_tag="RH288_002691"
     CDS             19805..20446
                     /locus_tag="RH288_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416282.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyrazinamidase/nicotinamidase"
                     /protein_id="HDV4031734.1"
                     /translation="MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRG
                     EAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQ
                     KAIAAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFT
                     VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQG"
     gene            complement(20539..21897)
                     /locus_tag="RH288_002692"
     CDS             complement(20539..21897)
                     /locus_tag="RH288_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4031735.1"
                     /translation="MEQYDQIGARLDRLPLARFHYRIFGIISFSLLLTGFLSYSGNVV
                     LAKLVSNGWSNNFLNAAFTSALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAAT
                     GAAFVPDMYWLIFFRFLMGTGMGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPM
                     LSAAIGVVVIAFFSWRIMFLLGGIGILLAWLLSGKYFIESPRWLAGKGQIAGAECQLR
                     EVEQQIEREKSIRLPPLTSYQSNSKVKVIKGTFWLLFKGEMLRRTLVAITVLIAMNIS
                     LYTITVWIPTIFVNSGIDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRLFGSTLLI
                     IIAVLGYIYSIQTTEWAILIYGLVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVN
                     AVGRIVAVFTPYGVAALLTHYGSITVFIVLGVMLLLCALVLSIFGIETRKVSLEEISE
                     VN"
     gene            complement(22015..22773)
                     /locus_tag="RH288_002693"
     CDS             complement(22015..22773)
                     /locus_tag="RH288_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV4031736.1"
                     /translation="MAAKDRIQAIKQMVANDKKVTVSNLSGIFQVTEETIRRDLEKLE
                     DEGFLTRTYGGAVLNTAMLTENIHFYKRASSFYEEKQLIARKALPFIDNKTTMAADSS
                     STVMELLKLLQDRSDLTLLTNSAEAIHVLAQSEIKVVSTGGELNKNTLSLQGRITKEI
                     ISRYHVDIMVMSCKGLDINSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFV
                     QLADFSHINYIITDKSPGAEWIAFCKDNNIQLVW"
     gene            complement(22910..23890)
                     /gene="ydjG"
                     /locus_tag="RH288_002694"
     CDS             complement(22910..23890)
                     /gene="ydjG"
                     /locus_tag="RH288_002694"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent methylglyoxal reductase"
                     /protein_id="HDV4031737.1"
                     /translation="MKKIPLGTTDITLSRMGVGTWAIGGGPAWNGDLDRQICIDTILE
                     AHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGD
                     RQLYKNLSPESIREEVEASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKAE
                     GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYS
                     PLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLAL
                     AWILKQSDLISILSGATAPEQVRENVAALIINLSDADATLMREMAEALER"
     gene            complement(23900..>24663)
                     /locus_tag="RH288_002695"
     CDS             complement(23900..>24663)
                     /locus_tag="RH288_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HDV4031738.1"
                     /translation="RIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVTEDG
                     ERTFVTNRNGSLWKLNIDDVDFSRFSQAELLSLASIFNSPLLDGKALTEIFTQAKTRQ
                     MIICADMIKPRLNETLDDICGALSYVDYLFPNYAEAKLLTGKETLDEIADCFLACGVK
                     TVVIKTGKDGCFIKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNLRECA
                     RFANATAAISVLSVGATTGVKNRKLVEQLLEEYEG"
BASE COUNT         6012 a         6409 c         6108 g         6134 t
ORIGIN      
        1 agtgcataaa cggcggaggc taactggaaa tcaaggagtt ataaccaaac catatgcatt
       61 taaagtgcat ataaagtgaa tacgtttgcg atgtgggtga ataaaaagaa taaaaaacgc
      121 aatgttatgc agaagtaaaa tataattctg gaattgtgat cattgacgaa atttactgga
      181 aattactgcg ccattctgac gcagcgcgca ccaaaagcgg gcattttttg cgccatcgtt
      241 gacatcatta acaaccatcg atcaaatcac ttaacaacag gcggtaagca acgcgaaata
      301 ctgctaccat ccacgcactc tttatctgaa taaatggcag cgactatgaa atttgtctct
      361 tttaatatca acggcctgcg cgccagacct caccagcttg aagccatcgt cgaaaagcac
      421 caaccggatg tgattggcct gcaggagaca aaagttcatg acgatatgtt tccgctcgaa
      481 gaggtggcga agctcggcta caacgtgttt tatcacgggc agaaaggcca ttatggcgtg
      541 gcgctgctga ccaaagagac gccgattgcc gtgcgtcgcg gctttcccgg tgacgacgaa
      601 gaggcgcagc ggcggattat tatggcggaa atcccctcac tgctgggtaa tgtcaccgtg
      661 atcaacggtt acttcccgca gggtgaaagc cgcgaccatc cgataaaatt cccggcaaaa
      721 gcgcagtttt atcagaatct gcaaaactac ctggaaaccg aactcaaacg tgataatccg
      781 gtactgatta tgggcgatat gaatatcagc cctacagatc tggatatcgg cattggcgaa
      841 gaaaaccgta agcgctggct gcgtaccggt aaatgctctt tcctgccgga agagcgcgaa
      901 tggatggaca ggctgatgag ctgggggttg gtcgatacct tccgccatgc gaatccgcaa
      961 acagcagatc gtttctcatg gtttgattac cgctcaaaag gttttgacga taaccgtggt
     1021 ctgcgcatcg acctgctgct cgccagccaa ccgctggcag aatgttgcgt agaaaccggc
     1081 atcgactatg aaatccgcag catggaaaaa ccgtccgatc acgcccccgt ctgggcgacc
     1141 ttccgccgct aatttagcag ctctcctggc tcaaactggg tcaggagaat taaccttgag
     1201 aaaaatcaac aaactgtcag taatgatttg ttgcctgccg tcctttgtta taccgtctct
     1261 gcgtttttag ttgtctgacc acttctctat tatcaagttt gatataggaa actccacgat
     1321 gaacgctgag cgtaaatttc tttttgcctg tcttattttt gcgctggtca tttacgctat
     1381 ccacgctttc ggtttattcg atctgctcac cgatttaccc cacttacaga cactcatccg
     1441 ccagagcgga tttttcggct atagcctcta tattctgtta ttcatcattg ccaccctctt
     1501 gctgttacca ggaagcatac tggtgatcgc gggaggaata gtttttggcc cgctcttagg
     1561 gacactactc tcattaattg ccgccacgct ggcctcctcg tgctcattcc tgctggcgcg
     1621 ctggctggga cgtgatttac tgctgaaata cgttggccat agcaatacct tccaggccat
     1681 tgaaaaaggc attgcgcgta acggtattga ttttcttatt ctgacccgct taatcccgtt
     1741 gtttccttac aatattcaaa attacgctta cggattaacc acaatcgcct tctggcctta
     1801 tacccttatt tcggcactca cgaccctacc cggtattgtt atttataccg tgatggcaag
     1861 cgatctcgcc aatgaaggca ttacgctgcg ctttatttta caactctgtc tggcgggcct
     1921 ggcgctgttt attctcgtcc agctcgcaaa actctacgcc cgacacaaac atgtggatct
     1981 gtctgcttcg cgccgcagcc cacttactca cccaaaaaat gaaggataga acgatgttgc
     2041 aacattattc agtgtcatgg aaaaaaggac tggctgcact ctgtttactg gctgttgctg
     2101 ggcttagcgg ctgcgatcaa caagagaatg cggcggcaaa agtggaatac gacggacttt
     2161 cgaacagcca accgctgcgt gtcgatgcca ataaccatac ggtaaccatg ctggtgcaaa
     2221 ttaatggtcg tttcctcacc gacgacactc gtcacggtat tgtgtttaaa gatggctcca
     2281 acggacataa atcgctgttt atgggttatg cgaccccgaa agcattttat gaagccctga
     2341 aagaggcagg tggtacgccg ggcgaaaaca tgacgatgga taataaagaa acgactcatg
     2401 tcacaggcag caaactggat atttcggtca actggcaagg ggcggcaaaa gcgtattcct
     2461 tcgatgaagt gattgttgac agtaatggca agaaactgga catgcgcttt ggcggtaatt
     2521 taacggcagc agaagagaag aaaacgggtt gcctggtgtg tctggatagc tgcccggtcg
     2581 gcatcgtcag caatgcaaca tacacttatg gtgcggttga aaaacgtggt gaagttaaat
     2641 tcaaaggcaa tgcctcagtt ctcccggcgg ataacacgct ggcaacggtt acctttaaaa
     2701 tcgccgaata aagccaggat aaaggatgat gatgatgcaa tcgcgaaaaa tctggtacta
     2761 ccgtataacc ctcatcatcc tgttgttcgc tatgctgctg gcatgggcgc tgcttcccgg
     2821 cgtccatgag tttatcaatc gcagcgttgc ggcgtttgcc gccgtggacc aacagggtat
     2881 agaacgcttt attcagtctt acggcgcact ggcggcagtt gtctcgttct tgttgatgat
     2941 tttgcaggcc attgctgcac cgctacctgc gtttttgatc acctttgcca atgcgtcgct
     3001 gtttggcgcg ttctggggcg gcttgctgtc gtggaccagt tcgatggccg gcgcggcgct
     3061 gtgctttttt atcgccagag tgatgggccg cgaagtggtg gaaaaattaa ccggcaaaac
     3121 cgtgcttgac agtatggacg gctttttcac tcgctacggc aaacacacca ttctggtctg
     3181 tcggttattg ccttttgtcc ctttcgatcc aatcagctat gctgccggtt tgacttcaat
     3241 acgttttcgc tcgtttttta tcgccaccgg gcttggtcag ttaccggcaa ctattgttta
     3301 ttcctgggcg ggcagcatgt taacaggcgg tactttctgg tttgtcaccg gactgtttat
     3361 tctgtttgcc ctgaccgtgg tgatttttat ggcgaagaaa atatggcttg aacgccagaa
     3421 gaggaatgcc tgatgggttt accgccgctt agcaaaattc ctttaatttt acgtccacag
     3481 gcgtggctgc atcgtcgcca ttacggcgag gtgctaagcc ccattcgctg gtgggggcgg
     3541 atcccgttta tcttttatct ggtgtcgatg tttgttggct ggctggagcg caaacgctca
     3601 ccgctcgatc cggtagtacg atcgcttgtc agcgcgcgca ttgcgcaaat gtgcctgtgt
     3661 gagttttgtg tggatatcac cagtatgaaa gtcgccgagc gcaccggcag cagcgataaa
     3721 ctgctggcag tggctgactg gcggcaaagc ccgctcttta gcgatgaaga acggctggcg
     3781 ctggagtacg ccgaagccgc aagcgtaacg ccgccaacgg tcgatgatgc cctgcgtacc
     3841 cgactggctg cgcattttga cgctcaggcg ctcaccgaac tgacggcatt gatcggcctg
     3901 caaaatctgt cagcccgttt taattctgcc atggacattc ccgctcaggg gctgtgccgt
     3961 attcctgaaa aacgttctta aggagagatg atgcgccatt gtgggtggtt gctgggattg
     4021 ttatcgctgt tttctctggc aacacatgcc agtgactggc aagaaattaa aaatgaggcc
     4081 aaagggcaaa ccgtctggtt taacgcctgg ggcggcgata ccgcaattaa ccgctatctc
     4141 gactgggtga gcggcgagat gaaaacccat tacgctataa acctgaagat tgtccgtctg
     4201 gcggatgccg cagacgcggt gaagcgcatt cagaccgaag ccgcagccgg acgtaaaacg
     4261 ggcggctcgg tggatctgct ctgggtgaac ggcgaaaact tccgcacctt aaaagaggcc
     4321 aatttattac aaacgggctg ggcggagact ctgcccaact ggcgctatgt cgacacacag
     4381 ctgccggtgc gggaagattt ttctgtgccg acacaaggtg cggaatcgcc ctggggcggc
     4441 gcacaactga cgtttatcgc ccgccgcgat gttacgccac agccaccaca aacgccgcaa
     4501 gccttactgg agtttgctaa agccaatccc ggcacggtta cctatccgcg cccaccggac
     4561 tttaccggca cggcgtttct tgaacagttg ctgattatgc tgacgcccga tcccgccgca
     4621 ttaaaagaag cgccggacga tgcgactttc gcccgtgtca ctgctccctt gtggcaatat
     4681 cttgatgtgc tgcatccgta tttgtggcgc gaaggaaagg atttcccgcc ttcacccgcg
     4741 cggatggatg ctctgctgaa agccggcaca ttgcgcctgt cgctgacctt taaccccgcg
     4801 catgcgcagc aaaaaatcgc cagcggcgat ttgcctgcaa gcagttacag ttttggcttt
     4861 cgcgagggga tgattggcaa cgtgcatttc gtcaccattc ctgccaacgc gaatgccagt
     4921 gctgcggcga aggtagttgc caatttcctg ctctcacccg atgcgcaact gcgtaaagca
     4981 gatcccgctg tctggggcga tccttctgtt ctcgatccgc aaaaactgcc tgacgggcag
     5041 cgcgaatcat tgcaatcaag aatgccgcag gatctgccgc cggtactggc tgaaccgcac
     5101 gcaggttggg taaatgcgct ggaacaagaa tggctacacc gttacggtac gcattaatct
     5161 ttttgctgtg ggcgatggtg gcggtgattt atgcaccgct gatcccggca gctctcacgc
     5221 tgatatcgcc tgctttgtcg ttgacacact ggcaggcgtt atttgccgat ccacagttac
     5281 cgcaggcatt actggcaacg ctggtgtcga caaccatcgc ggcggtcggg gcattgttga
     5341 ttgccctgct ggtgattgtg gcgctgtggc ctgggccgaa atggcagcgt atgtgcgccc
     5401 gtctgccgtg gctgctcgcc attccccatg tggcttttgc caccagcgcc cttctgctct
     5461 ttgctgacgg agggctgctt tatgactatt tcccgtattt cactccgcca atggaccgat
     5521 ttggcatcgg tctgggcctc acccttgcag tgaaagaaag cgcatttctg ctgtggatct
     5581 tagcagcagt attgagcgaa aaatggctgt tgcagcaggt cattgtgctg gattcgctgg
     5641 gctacagccg ctggcaatgc ctgaactggc tgctgttgcc ctccgtcgcg cctgcgctgg
     5701 caatggcgat gctggcgatt gttgcctggt cgctgtcggt cgtggatgtg gcaattattc
     5761 tcgggccagg taatcccccg acgctggcgg taattagctg gcagtggtta acccagggcg
     5821 acattgacca acaaacaaaa ggcgcgcttg ccagcctgct gttgatgctg ttactcgccg
     5881 cctacgtttt gctgagctat ctgctatggc gcagctggcg gcgcactatt ccccgcgtag
     5941 atggcgttcg caagcctgcc acgcctttat tgccgggcaa tacgctggcg atttttttac
     6001 ccttaaccgg tgtgctgtgt gtggttctgc tggcgatcct cgcggatcag tcgacgatca
     6061 atagtgaagc gctcatcaac agcctgacaa tggggctggt ggcgacattc atcgctttgc
     6121 tcctgttact gctgtggctg gaatgggggc cacagcgtcg ccagttgtgg ctatggttgc
     6181 ccattttatt acctgctctg ccactggtgg cgggccagta cacgctggcg ctatggctga
     6241 aactggatgg aagctggacg gcggtggtct gggggcatct gctgtgggtg atgccgtgga
     6301 tgctgtttat cctgcaaccc gcctggcagc gcattgattc acggttaatt ttgattgcgc
     6361 aaacactggg ctggtcgcgg gccaaaatct tcttttacgt gaaatgccca ctcatgttgc
     6421 gccctgtgct gattgccttc gcggtgggat ttgcagtcgg tattgcgcag tatatgccaa
     6481 cgctgtggct gggcgcgggg cgttttccga cgctcaccac tgaggcggtg gcattaagca
     6541 gcggcggcag caacggtatt ctcgccgccc aggctttatg gcaactgcta ttaccgctta
     6601 ttatttttgc cctgaccgcg ttagtcgcaa aatgggtagg ttatgtcaga caaggactcc
     6661 gctaatgctc tgcgtgaaaa atgtttcgct acgtttacca gaaagccgct tgctgacaaa
     6721 cgttaacttt acggtggata aaggtgacat tgtcacgtta atggggccgt ctggctgtgg
     6781 aaaatccact ctgttttcat ggatgattgg tgcactggcc gaacagtttt cttgtacagg
     6841 tgagctatgg ctcaatgagc aacggattga catcctaccc accgcacagc gtcagattgg
     6901 cattcttttt caggatgcac tgttatttga ccagttcagt gtcgggcaaa atttactgct
     6961 ggcgctaccg gcgacactta aagggaatgc ccgacgtaat gccgtgaatg atgcacttga
     7021 gcgttcaggc cttgagggag ctttccatca ggatcctgcc actttgtctg gcggtcagcg
     7081 agcgcgcgtt gctctactac gcgcccttct cgcccaacca aaagcgttac tcctggatga
     7141 gccattcagc cgtcttgatg tggctctgcg cgataatttt cgccagtggg tgttcagcga
     7201 agttcgcgcc ctggcgatcc ccgtcgttca ggtaacgcac gatctccagg atgttcctgc
     7261 tgatagttct gttctggata tggcgcagtg gtcagaaaat tacaacaaac tgcgataacg
     7321 caaagttttt ctcaatgcgt cagttcagaa tggcgcactc aaaactacaa tgtcgggatt
     7381 ttcgatgaaa cgtgtttctc aaatgaccgc gctggcaatg gctttagggc tggcttgcgc
     7441 ttcttcgtgg gccgctgaac tggcgaagcc tcttacactt gaccagcttc aacaacaaaa
     7501 tggcaaagcg atagatactc gccccagcgc gttttataac ggctggccac aaaccttaaa
     7561 tggcccttct ggtcatgaac ctgccgcctt aaacctctct gccagctggc ttgacaaaat
     7621 gagcaccgaa cagctcaacg cgtggatcaa gcaacataac ctgaaaaccg atgctccggt
     7681 ggcgctgtac ggtaatgaca aagatgtcga cgccgtcaaa acgcgactgc aaaaagcagg
     7741 tttaacgcat atctccatcc tgagtgacgc gctaagcgaa ccttcccgtc tgcaaaaact
     7801 gccgcatttt gagcagctgg tttatccgca atggctgcac gacctgcaac aaggtaaaga
     7861 ggttacggcg aaacctgccg gtgactggaa agtcattgaa gcggcctggg gcgctcctaa
     7921 gctttacctt atcagccata ttcccggcgc tgactacatc gataccaacg aagtggaaag
     7981 tgaaccgctg tggaacaaag tttctgatga acaactaaaa gcgatgctgg caaaacacgg
     8041 cattcgccat gacaccacgg tcattctgta tgggcgtgac gtatacgctg cagcgcgtgt
     8101 ggcgcagatt atgctttatg ctggcgtgaa agatgtgcgc ctgctggatg gcggctggca
     8161 aacctggtcc gacgcgggac tgcctgttga gcgcggaacg ccaccgaaag tgaaagcgga
     8221 accggatttc ggcgtgaaga tcccggcaca accgcagttg atgctcgata tggaacaggc
     8281 ccgtggactg ctgcatcgcc aggatgcatc gctggtgagc attcgttcgt ggccagaatt
     8341 tatcggtacg accagcggtt acagctatat taaaccaaaa ggtgaaatag ccggcgcacg
     8401 ttggggacac gctggtagcg actcgacgca tatggaagat tttcataacc cggatggcac
     8461 catgcgcagc gccgatgata ttaccgctat gtggaaagcg tggaatatca aaccagagca
     8521 gcaagtttca ttctactgcg gcaccggctg gcgcgcgtcc gaaaccttta tgtacgcacg
     8581 cgccatgggt tggaagaatg tttccgtgta tgacggcggc tggtacgaat ggagcagcga
     8641 tccaaaaaat ccggtagcaa ccggtgaacg cggcccggac agtagcaaat aacattgcaa
     8701 ttactgacgc tggagcgact tcagcgtcag atacccactc cacacccgcg taaaggtcgt
     8761 catccagcac aacgcaccga agatccacgc aaaccacgca aaccatgcag ggaataaaca
     8821 tcccagcaca aacagtaaga tcgtttctgt gccttcggtt aatcccccca gatagtaaaa
     8881 cgacttatgt gcataaccgg ggttatcaat ctgatgtttt gctgccagtg cagcaaaggc
     8941 gagaaaactg ctgcccgtgc cgataaacgc aaacaacaac cagccgcctg ccagcgcatt
     9001 ttgctccggt gcagcaagaa taaagccaaa cggcaccagc gcgtaaaaga gaaaatcgag
     9061 agaaatatca agaaagccgc ccgcgtcggt aagctctctg cgccgcgcca gcgcaccgtc
     9121 cagaccatca agcagcctgt tcaacaaaat gacgactagc gccgccagat accagcccag
     9181 cgccagaaac ggcagagcca gcacgccgat ggcaaatccc actaatgtta aaccatctgg
     9241 cgtaatgccc ggtttatcaa gaacccgcac gcactgatgc aacaacggtt taatccgggg
     9301 atgaagatgg cggtctagca caggcactcc ttaaatataa agcctttctg attgagcaac
     9361 agtgcggata ttatggcatt tttcgcttat ctgcccgtgt gtaatttatg aaaatgattg
     9421 aagttgttgc cgccatcatt gaacgtgatg gcaaaatttt actcgcgcaa cgccccgccc
     9481 agagcgatca ggcgggatta tgggagtttg ccggtggtaa agtcgagccg gatgaaagtc
     9541 agcggcaggc gctggtgcgt gagttacgcg aagaactggg catcgaagca actgtgggtg
     9601 aatatgttgc cagccatcag cgagaagttt cggggcggat tatccatctt catgcctggc
     9661 acgtacccga cttccacggg acgttacagg cacatgaaca tcaggcgctg gtctggtgct
     9721 cacctgaaga ggcgctgcaa tatccgctgg cccctgctga cattccatta ttagaggcgt
     9781 ttatggcttt acgcgccgcc agaccagcgg attagtgcta agggttttgt catcacgctg
     9841 gcattgcagc agtattcctt cggctttaat taccgcccct tcagaataat tttgatcctg
     9901 ataaacgcag cactgagtac agggctgcgc tgactgcccg cctgaactga acacttctgg
     9961 cggtacgttt acctccacgt ccggacgata atgcgggtta gccagtgcaa ttaatggaaa
    10021 tgctaatact acggcgaaca atgctcgact cacagggaac tccttaacgt tattgtctct
    10081 gctactgata acggtagccg ggtggcaaaa ctttagcgtc tgagttatcg catttggtta
    10141 tgagattact ctcgttatta atttgctttc ctgggtcatt tttttcttgc ttaccgtcac
    10201 attcttgatg gtatagtcga aaactgcaaa agcacatgac ataaacaaca taagcacaat
    10261 cgtattaata tataagggtt ttatatctat ggatcagaca tattctctgg agtcattcct
    10321 caaccatgtc caaaagcgcg acccgaatca aaccgagttc gcgcaagccg ttcgtgaagt
    10381 aatgaccaca ctctggcctt ttcttgaaca aaatccaaaa tatcgccaga tgtcattact
    10441 ggagcgtctg gttgaaccgg agcgcgtgat ccagtttcgc gtggtatggg ttgatgatcg
    10501 caaccagata caggtcaacc gtgcatggcg tgtgcagttc agctctgcca tcggcccgta
    10561 caaaggcggt atgcgcttcc atccgtcagt taacctttcc attctcaaat tcctcggctt
    10621 tgaacaaacc ttcaaaaatg ccctgactac tctgccgatg ggcggtggta aaggcggcag
    10681 cgatttcgat ccgaaaggaa aaagcgaagg tgaagtgatg cgtttttgcc aggcgctgat
    10741 gactgaactg tatcgccacc tgggcgcgga taccgacgtt ccggcaggtg atatcggggt
    10801 tggtggtcgt gaagtcggct ttatggcggg gatgatgaaa aagctctcca acaataccgc
    10861 ctgcgtcttc accggtaagg gcctttcatt tggcggcagt cttattcgcc cggaagctac
    10921 cggctacggt ctggtttatt tcacagaagc aatgctaaaa cgccacggta tgggttttga
    10981 agggatgcgc gtttccgttt ctggctccgg caacgtcgcc cagtacgcta tcgaaaaagc
    11041 gatggaattt ggtgctcgtg tgatcactgc gtcagactcc agcggcactg tagttgatga
    11101 aagcggattc acgaaagaga aactggcacg tcttatcgaa atcaaagcca gccgcgatgg
    11161 tcgagtggca gattacgcca aagaatttgg tctggtctat ctcgaaggcc aacagccgtg
    11221 gtctctaccg gttgatatcg ccctgccttg cgccacccag aatgaactgg atgttgacgc
    11281 cgcgcatcag cttatcgcta atggcgttaa agccgtcgcc gaaggggcaa atatgccgac
    11341 caccatcgaa gcgactgaac tgttccagca ggcaggcgta ctatttgcac cgggtaaagc
    11401 ggctaatgct ggtggcgtcg ctacatcggg cctggaaatg gcacaaaacg ctgcgcgcct
    11461 gggctggaaa gccgagaaag ttgacgcacg tttgcatcac atcatgctgg atatccacca
    11521 tgcctgtgtt gagcatggtg gtgaaggtga gcaaaccaac tacgtgcagg gcgcgaacat
    11581 tgccggtttt gtgaaggttg ccgatgcgat gctggcgcag ggtgtgattt aagttgtaaa
    11641 tgcctgatgg cgctacgctt atcaggccta caaatgggca caattcattg cagttacgct
    11701 ctaatgtagg ccgggcaagc gcagcgcccc cggcaaaatt tcaggcgttt atgagtattt
    11761 aacggatgat gctccccacg gaacatttct tatgggccaa cggcatttct tactgtagtg
    11821 ctcccaaaac tgcttgtcgt aacgataaca cgcttcaagt tcagcatccg ttaactttct
    11881 gcgatagcag cagatatgcc agtaaagaaa tcccatttga ctattttttt gataatcttc
    11941 ttcgctttcg aacaactcgt gcgcctttcg agaagcaagc attatataat gccaggccag
    12001 ttcttcttca attgtcccgt tttgaaaagc tgtgcttgat atcgagatca tccatgataa
    12061 ttccgccgcc catattagct tcgccgagga tttaccggag ctatgattag cgcaatcaga
    12121 gatatagtct gagggaaaaa cagcaaattt attcaacaag gcgataacct gctctggggc
    12181 ttcctccatg tttgctttaa aggtattggc tccatggtcg ccagaaagaa aatgctccat
    12241 taaggcacaa taactttcgc tatcttcgat accccattga tcctctaaag actcgcgtct
    12301 tttacttatg atatcgatcg agtcaaaagg aagcacatga tattggaagg tatctttgcc
    12361 aggttcaggc tttcgcggcc agaactccag cgtttcagac cattgcttat gatagaatcg
    12421 ataaggtgcg atcaattgta gcgcctgtaa cttctcgata ctgagcggct caataccttt
    12481 agcctgataa taatgcagtt gttctttttt tgctttaaaa ccggcccgaa caataagccc
    12541 catcataatt aatagataaa gaaaagagca tcccgcggta atcaggcctc tttcattcaa
    12601 accgttggat gttatcgctg cgaacacaaa cattacagcg acaacacatg ttaaataaaa
    12661 cccccactta caaagcagca tggccttatt ttctttaatc atccgttcaa aattactatt
    12721 aaatatttcc cagccattaa aagaatactt ctcgctccca ggatggtttt gtaataaaac
    12781 ttttttcatc acattccctg ttattacata ctttagaggc gataatttta tccatgcaaa
    12841 aaaaatatcc aacgaatttt cttgatccgc tggatatttc agaatatgac tcgaatagca
    12901 cgaaagattc actcgcttac gctatcgccc cgcttccgac ttcatctgct ggcggacttt
    12961 ttttcgcact acgtttacgc ggtgcagcct ttttcttatc agcactgcca ccactgcccg
    13021 gagccacaat gccgcgaaac tgccgcaccg gcgtacgttt ggcttgatca ataagctgat
    13081 atagcgtccc caccagcggc tgcataaagt cctgatagcg acactgcttt tcgctgattt
    13141 gcgtcagcac cgattcccag tgcgcggtca tgtccggtcg cgtcgccatc tccggcagcg
    13201 aatggaatag cgcttttccg gcgtcggtgg agtggatata gcgccctttt ttggtcagga
    13261 aaccacgctt gaacaacagt tcaataatcc cggcacgcgt tgcctctgtc cccagaccat
    13321 cggtcgcacg gaggatcttt ttcagatctt tatcctgcac aaagcgcgcg atcccggtca
    13381 tcgccgaaag cagtgttgca tcggtaaaat ggcgcggcgg ctgggtttgc cgctctacca
    13441 cttcaccttt ttcacacagc aactcatcgc ctttcgccac cacaggcagt ggcgtgccgt
    13501 cgttttcttc atcgcgctct ttgctgccta acagcgtgcg ccagcctgct tcagcaagaa
    13561 aacgcgcttt agcgacaaat ttgcctttgg caatgtgcag ttcgataaca cacttgcgga
    13621 acaccgcatc cgggcagaat tgcatcagat actgacgggc aatcaggtta tagaccttcg
    13681 cttcgttctc cgtcaggttg atcgcagaac tccgtgcggt cggaatgatg gcgtggtgcg
    13741 catcgacctt tttgtcatcc caacagcggt tgcgtatatc tggatctacc actggctgcg
    13801 gcaacagatc cggtgcatga acactgatgg cattcatcac cgcgtggcgt ccggcaaaat
    13861 gttcttctgg caaatagcga caatcagaac gcggataagt gattagcttg tgcgtttcgt
    13921 acagtttctg gcagatatca agcacgttct gcgcactcag accaaaacgt tttgccgctt
    13981 caatctgcaa cgctgaaagc gaaaaaggca gcggcgcgga ttctgattcc cgtttatcgt
    14041 tatagctggt gacaatagcc ggttgaccac taatgcggtt aaccacatgc tccgccagtg
    14101 gacgatgtaa caagcgccct tcttcatcct ggtacggttc acacgcttcg ctcggttgcc
    14161 agatagcggt aaaccgctca tcggcaggtg tcacgatatg tgctttgact tcaaagaagt
    14221 ctttcgccac gaagttttca atctcttcat cgcggcgcac caccagccca agcacgggcg
    14281 tctgcacgcg tcccacggaa agtacgccct gataaccggc attgcgaccg agaatggtat
    14341 acgcacgggt catattgatg ccgtacagcc agtcggcacg cgctcgcgcc agcgcagaaa
    14401 cgcacagcgg tacaaactca ctgttggaac gaagacggtc gatcgcccgc tcaaccgcct
    14461 gcgggttcag gtcgtttatc aagcaacgct gtacctgctg gcgcttttcc ggtgccagtt
    14521 gcagatagtc cagcacttca tccaccagca attgcccttc acgatccggg tccccggcgt
    14581 gaacgatttc gctggcttca tgcaggaacc gtttgatgac gttaagttgt ttggtcacgg
    14641 agggtcgggg ctgtaattgc cacttttccg ggacaatcgg caaatccgca agattccagc
    14701 gcgcatagcg gctgtcgtag gcgtctggct gcgcctgctc aagcaggtga ccgatacacc
    14761 aggtcaccac ctgaccatta ccgcactcga taaagccatc gcctttccgg tgcggtttgg
    14821 gcaggacatc agcaatggcg cgcgccagac tcggtttttc ggcaataaac aaccgcattg
    14881 aattaacgaa tctcaaccat ggcacgaccg ccgcgcgctg gcaccagttc gccaattgcc
    14941 gtcagttcaa tgccaaactc ggcggctgta gctttgacct cattttctgc ttccggcatg
    15001 accgccagca gcaaaccgcc agaagtttgc ggatcacaca gcagatcgcg cacttcacgc
    15061 ggcatttcac ccatcagatg accgtagctg gcaaagttac gttcagtgcc gccaggtact
    15121 gcgcccaact taatgtactc ttcaacaccg gggagtttcg ggatcgcttc atagtcgacg
    15181 cgtgcctgca caccagcccc ctgacacatt tcgctcaagt ggcccagcag accaaagccc
    15241 gtaacgtcgg tcatcgcttt tacgccttcg atgttggcaa aggacgcgcc tgcgatgttc
    15301 atccggcaca tcacttccgt cgccagtccc tgatgttctg gtttcaacag tgattttttc
    15361 tcagccgtgg taagaacgcc gatccccagc ggtttcgtca ggaacagttt gcatccggct
    15421 tgtgcggtac tgtttttctt cacccgctcg gtcggtacga tccccgttac cgccagacca
    15481 aaaatcggct ccggcgcatc gatggagtga ccgccagcca gcgcaatacc cgcctgacga
    15541 catgcatagc gtccaccttc ggtcacttcg cgggcaattt ctggggaaag tttgttaatc
    15601 ggccagccga ggatcgcaat cgccataatc ggtttgcccc ccatcgcgaa gatatcgctg
    15661 atggcgttag tcgccgcaat gcggccaaaa tcgaaaggat tatcaacgat cggcataaag
    15721 aagtcggtgg tactgataac gctggtgcca ttgcccagat cgtacaccgc cgcatcgtcg
    15781 cgggtttcat tacccacaag caaattcgga tcaacaaact tcgcctgctc actgtgcagg
    15841 atggtttcca acacttttgg ggaaatttta cagccgcaac cagctccgtg gctgtattgg
    15901 gtcaaacgaa tcgagttctc gctcatggac atctcctgtc aatgcaatcc gggtatggta
    15961 accctcattc cgtgaagtga taagtgagag tgtctgaatt cctgcgcctt tgctcacaat
    16021 ccagacagtt tcgcgacaat tatcagaaat aagttacaaa cggcgtcggg tccgggacgt
    16081 taatcgacgt agatgctttc agctgcggcg taccgaggta gagaaaaccg acaattttat
    16141 cctgctcacg gcaaccgaat gcttcacgca ctaccggact ttcagttaat gcgccactgc
    16201 gccagatgcc gccaaacccc tgggcaactg ctgccatttg catcgccatg accgcgcatc
    16261 cggcagacat ttcctgttcc cagcgcggga ctttatgatt ctcttcgcat ttcgccacca
    16321 ccgtgatgat gagcggtgcg cggaacggcg cattacgggc tttgtcgata gctttgtcat
    16381 cactaccggc agcaatcgcc ccctgttcca gtacggcgct gaaacgctcg cgcccttccc
    16441 cttcaatcac aaaaaaatgc cacggttgca tggacttatg gtccggcgca cgcatacccg
    16501 cacgcaggat gttttgcagt tgttcacccg ttggcgcggg ttcagccaag cgggaggcgc
    16561 tacggcgatt gatcaatagt tcgagtgcat ccatttgatt aactcctgtc gtgatattta
    16621 ttcacaaaat taacacgaga gtggattttg ttacagcaca gtccgcaatt cctgctgaca
    16681 agtaccggtt gggtcattac gataaccaca tctattgcgc ctgtgacagg tgtgacctta
    16741 agttgggaga atacatgcga accctttggc gatttattgc cggatttttt aaatggacgt
    16801 ggcgtctgct gaatttcgtc cgtgaaatgg tacttaacct gttctttatt ttcctcgtac
    16861 tggttggtgt ggggatttgg atgcaggtca gtggtggtga ttcgaaagaa acggccagtc
    16921 gtggcgcact gctgctggac atttctggtg tgatcgtcga taaacccgac agttctcagc
    16981 ggtttagtaa attaagccgc cagctgcttg gtgccagttc cgatcgtctg caggaaaact
    17041 cactgtttga tatcgtcaac actattcgcc aggcgaagga cgaccgcaat atcaccggta
    17101 ttgtgatgga tctgaaaaac ttcgcaggcg gcgaccaacc gtctatgcag tacatcggca
    17161 aagctctgaa agagtttcgt gacagcggga aaccggttta tgccgttggc gagaactaca
    17221 gccaggggca atattatctc gccagtttcg ccaataaaat ttggctgttt ccgcaaggcg
    17281 tggttgatct gcacggcttt gccaccaacg gtctgtacta caaatcgttg ctggataagc
    17341 tgaaagtttc cacccatgtg ttccgcgtgg gtacgtataa atctgccgtt gaaccgttta
    17401 ttcgtgatga tatgtcaccg gcagcccgcg aagctgacag ccgctggatt ggtgagctgt
    17461 ggcaaaacta tctgaatact gttgccgcta accggcagat ccctgctgag caggtattcc
    17521 ctggcgcgca agggttgctt gagggtttaa ccaaaaccgg tggcgatacc gcgaaatatg
    17581 cactggaaaa caagctggtc gatgcactgg catcgagtgc ggaaatcgaa aaagcactga
    17641 ccaaagaatt cggctggagt aagactgata aaaattatcg cgccatcagt tattacgatt
    17701 acgcattgaa aacgccggca gataccggtg acagcatcgg tgtcgtcttt gctaatggcg
    17761 caattatgga tggcgaggaa actcagggga atgttggcgg tgataccact gcggcacaaa
    17821 tccgcgacgc tcgccttgac ccgaaagtga aagcgattgt cctgcgtgtt aatagcccag
    17881 gcggcagcgt taccgcgtct gaagtgattc gcgctgaact ggcagcagcc cgggcagcgg
    17941 gtaagcctgt ggttgtatcg atgggcggca tggcggcatc tggtggttac tggatttcca
    18001 cgccagctaa ttacattgtg gctaacccca gcaccctgac cggttctatc ggtatcttcg
    18061 gcgtgatcac caccgtagaa aatagtctgg attcgattgg tgttcatacc gatggtgtct
    18121 caacttcacc gctggcagat gtttctatca ccagggcact gccgccggaa gcacagcaga
    18181 tgatgcagtt aagcattgag aatggctata aacgctttat cacgctggtt gctgatgcgc
    18241 gtcattcgac gccggagcag attgataaaa tcgcccaggg ccacgtctgg accggtcagg
    18301 atgcaaaagc taacgggctg gtcgatagcc tcggggattt cgatgatgca gttgccaaag
    18361 cagcagagct ggcaaaagtg aaacagtggc atctggaata ctacgttgat gaaccgacct
    18421 tcttcgacaa agtgatggac aacatgtctg gttctgtccg ggcaatgttg ccagatgcgt
    18481 tccaggccat gttacctgca ccgctggcct cggtagcctc tactgttaaa agtgaaagcg
    18541 acaagctggc cgcgtttaac gacccacaaa accgttatgc gttttgcctg acctgcgcca
    18601 acgtgcgtta agtcttgtac tgagtggccg acagatcgtc ggccacatta ttttttacgt
    18661 cgacgaatcc tcttcccgct gtctcgcccc atatttcctt atccgcatag tatcaggtgc
    18721 gctcctcctg cctcacgtat atacttttgc tctttcgata tcattcatat caatatcatg
    18781 caaaagaaat caatttacgt cgcctacacg ggcgggacca tcgggatgca gcgttccgag
    18841 cagggttata ttccggtgtc aggtcatcta caacgccaac tggcgctgat gccggaattc
    18901 catcgcccgg agatgccaga tttcaccatt catgaatata cgccgttgat ggattcttct
    18961 gatatgactc cagaagactg gcagcatatt gctgaagata ttaaagcgca ctatgacgac
    19021 tatgatggtt ttgtcattct gcacggcacc gatacgatgg catataccgc ctctgcgctg
    19081 tcgttcatgc tcgagaatct cggtaaacca gtcattgtga cagggtcaca aatcccgcta
    19141 gctgagttac gctctgacgg acaaattaat ctgctgaatg cgttgtacgt tgcggcgaat
    19201 tatccgatca acgaagtaac gctctttttc aataaccgat tgtatcgcgg caaccgcact
    19261 accaaagccc atgccgatgg ttttgatgcg tttgcctctc caaaccttcc tccgttactg
    19321 gaagcaggta tccatattcg tcgtttaaat acgccacccg ccccgcacgg tgaaggggaa
    19381 ttaatcgttc atccaatcac cccacaacca attggcgtag tgacgattta tccagggatt
    19441 tctgctgacg tcgtgcgcaa ttttctgcgc caaccggtga aagcattgat tttgcgctcc
    19501 tatggcgtgg gtaatgcgcc acaaaacaaa gccttcctgc aggaattaca tgaagccagc
    19561 gatcgcggta ttgtggtggt caacctgaca caatgtatgt ccggtaaagt gaacatgggt
    19621 ggttatgcca ccggtaacgc cctcgcccat gccggcgtta ttggcggtgc agatatgact
    19681 gtagaagcca cgctaaccaa actgcattac ctgctgagcc aggaactgga tactgaaacc
    19741 attcgcaagg ccatgagcca aaacctgcgc ggcgaactga cgccggatga ttaaggagac
    19801 tgcaatgccc cctcgcgccc tgttactggt cgatttacaa aatgatttct gtgctggtgg
    19861 cgcgctcgcc gtgccggaag gtgacagtac ggtggatgtc gctaaccgcc tgattgactg
    19921 gtgccagtcg cgcggtgaag cggttatcgc cagtcaggac tggcacccgg cgaatcacgg
    19981 cagttttgcc agtcagcacg gtgtagagcc ttatacgcca ggccaactcg acggtttgcc
    20041 acaaaccttc tggccagatc actgtgtgca gaacagtgaa ggcgcacaat tacatccgtt
    20101 actgcaccaa aaagcgatcg cagcggtgtt ccataaaggc gaaaatcctt tagttgacag
    20161 ttacagtgcc ttttttgata acggccgtcg gcagaaaacc tctctcgatg actggttacg
    20221 cgatcatgaa atcgatgaat tgatcgttat gggcctggct actgactatt gcgtgaagtt
    20281 taccgtgctg gacgcgttac agttaggtta taaggtaaac gtgattaccg atggttgtcg
    20341 tggcgtgaat atccagccac aggacagtgc gcacgcgttt atggagatgt cagctgctgg
    20401 ggcaacgcta tatacgctgg cagactggga agagacacag gggtaatttt acgctggcct
    20461 acaattctgt actggcattg taggccaaat aaaacacgtc agtggcacat ctggcaattg
    20521 atgccatcaa cgaaagattt aattcacctc agaaatctct tccaacgaca ccttccgcgt
    20581 ttcgatgcca aaaatggaga gaaccagcgc acagagcaat aacatgacac caagtactat
    20641 aaacaccgtg atcgacccat aatgtgttaa taatgccgca acgccatagg gcgtgaagac
    20701 tgcgacgatc cgtccgacgg cattaacgaa acccgaaccg cgcaggcgta aatgcgttgg
    20761 ccaaagctcc gggatataaa ccgccgacgc gaagcaaaca tacatgtata aaaagaagat
    20821 catcaccagg ccatagatta aaatcgccca ctctgtagtc tgaattgaat agatatagcc
    20881 taacacggca ataataataa gtaaggtgga gccaaataac cgacgaggaa aatgatcaat
    20941 aattaatgcc gcaataaata ttcctaccgg agcgccaatc ataataacag cggtcattaa
    21001 tattgattta tcgacatcaa tgccggagtt aacaaatatg gtcggtatcc atacggtgat
    21061 ggtataaagc gaaatgttca ttgcaattaa aacagtaatc gcgactaatg tacgtcgtaa
    21121 catttcacct ttaaacagga gccagaaagt acccttgatt actttaactt tgctgttgct
    21181 ctgatacgaa gtaagcgggg gtaaacgaat actcttctct ctttcaattt gctgctctac
    21241 ttcacgaagt tggcattctg cacctgcgat ttgccctttc cctgccagcc atcgtggcga
    21301 ctcaataaag tatttacctg agagaagcca ggctaacagt atgccaatac cacccaacag
    21361 aaacattatc cgccaactaa aaaaagcgat aaccaccaca cctatcgccg cagacagcat
    21421 gggcgaccag ttaccaacaa atgagagccg cgcggaccat tttccacgca ccgtcgcggg
    21481 gataaactcc gtaaatgagg catagccaac cataatcagc gcccccattc ctgttcccat
    21541 caggaagcga aagaagatga gccagtacat atcagggaca aaagcggccc ctgttgcagc
    21601 aataccgacg atgagaagat ttatgcgaaa cgccctgcgc cgcccaaagt aatcaccgat
    21661 gaacccaccg gtaagagagc cgatgaaata accaaacatt aatgccgagg taaaggcggc
    21721 attgaggaaa ttatttgacc atccattgct taccagcttt gctaagacaa cattaccgga
    21781 gtaactcaaa aaacccgtta ataacagact aaagcttatt ataccaaata tacgataatg
    21841 aaaccgggcc aaaggcaagc ggtccagtct tgcgccaatt tgatcatatt gttccattgg
    21901 gtgcctcgga tttgctaaaa aaggtagcaa ttgcggcaaa ttcacttgcc gcatctttat
    21961 catcatttta tttcaaggcg caggaacaaa taatattgac aacgtgtgct taaattacca
    22021 caccagctgg atattattgt ctttgcaaaa tgctatccac tctgcacccg gtgatttatc
    22081 agttattatg taattaatat gactaaaatc agctaactgg acaaaagctt tgcgatcaaa
    22141 cttagagtga tcaaccaata acgcaacttc tgtcgcctga cggatcattg tctttttgat
    22201 ttcagcttcc gcttcattag agtccagcgc gccgctgtta atatcaagac ctttacaact
    22261 cattaccatg atatcgacat gatagcggct gatgatctct ttagtaattc ttccttgcag
    22321 tgaaagtgta tttttgttta gttccccacc cgttgaaacg actttaattt ctgactgagc
    22381 cagaacatga atcgcttccg ccgagttggt tagcaacgtc aggtcactac ggtcctgtaa
    22441 caatttgagc aattccatta cggtactact ggaatcggct gccatggtgg ttttattgtc
    22501 gataaagggt agtgccttgc gtgcaataag ctgcttctct tcataaaacg atgaagcgcg
    22561 cttataaaaa tggatattct ccgtcaacat cgctgtattt aaaacagcac caccataggt
    22621 tctggtcaaa aagccttcat cttccagctt ctcaagatcg cggcgaatgg tttcttcggt
    22681 tacctgaaaa atcccactca aatttgagac tgtcactttt ttatcgttgg caaccatttg
    22741 cttaattgcc tgaatcctgt cttttgccgc cacgattaca cccctgtatc tttttacatc
    22801 acattagcgc gattatcgca taaccgatgt ttactttcaa aacaacctgt ttgaatcaca
    22861 gattttcatc acagttttca cagaaacaga ggtgaatcgt gttgagtatt taacgctcca
    22921 gggcctctgc catttccctc atcaatgttg cgtctgcatc cgataagttg ataatcagtg
    22981 ccgcgacatt ttcgcgtacc tgttccggtg cagtagcccc actaagaatg gagattaaat
    23041 cactctgttt taatatccac gccagtgcca gagtgggaat tgtgcactga taacgagcac
    23101 aaagtggctg ccactgttca agcatatcaa tcactttcag catgttttca cgctggaacc
    23161 agactttatt tgcccgagcg ccgcccggaa cgtaatcacg agtgatggtg ccggtcaaca
    23221 atccctgctc tagcggggaa taaacctgaa ccacaatgcc attatcacga catagcggca
    23281 gcagttcgtt ttccattgcc cggtcgagga tactgtattt cgcctgaata atatccagtt
    23341 caccatattg cagatactcg cggatatggt cagcatcgac gttagcagcg cctatagcgc
    23401 gaattttccc ttcagccttc aactcattaa gcactgcgac agtttcagcg atcggcgtaa
    23461 aaaatggcgg caccgactgc cagtgcgtca tgtagatatc gatgtaatca atacccagac
    23521 gttgcaagct ggcttctacc tcttcgcgga tagattccgg ggaaaggttt ttatacaact
    23581 gccgatcgcc aactttgttg aataaacttc cttttcgttc ccagacaatg ccgcatttgg
    23641 tttctactac aacctgttca cggggcagtt tttttaacgc ctgaccgacg ataacttcac
    23701 tattgccaaa gttatatcct ggcgcagtat caatcagatt aatgccgcaa cgatgggctt
    23761 caagaatcgt atcaatacat atttgccgat cgagatcgcc attccatgca ggaccgccgc
    23821 caatggccca tgtccccacc cccattcgcg aaagcgtaat atccgttgtg cctaaaggta
    23881 tctttttcat ttgccttcat tatccttcgt attcttccag caattgttcg accagctttc
    23941 tgttttttac gccggtggtg gcaccgacgc ttagaaccga gatagccgcc gttgcattgg
    24001 caaagcgtgc gcattcacgc agatttttgc cttctaacag tgccgcaata aaacctgaag
    24061 caaagttatc gcccgcgcca atggtgtcga tggcggttat tcctgcgacc gccggcacct
    24121 tcatcgtcat gtcaccacgc ttgataaagc agccgtcttt acccgtttta atcaccaccg
    24181 tttttacgcc gcacgcaaga aagcagtcag caatttcatc caatgtctct ttcccggtga
    24241 gtaattttgc ctcggcataa ttaggaaaca gataatcgac ataactcaat gctccgcaaa
    24301 tatcatccag cgtttcattc aaccgcggtt tgatcatatc ggcacagata atcatctgcc
    24361 gggttttagc ttgcgtaaaa atttctgtta gcgctttacc atccaataga ggactgttga
    24421 aaatactggc cagagataat aattccgcct gagaaaaccg cgaaaaatca acatcgtcaa
    24481 tattcaattt ccacagactg ccgttacggt ttgtgacaaa cgtccgctcg ccatcctccg
    24541 tcaccagtcc aacgttaata gaggtatcta tgctgacgtc ctgcttcagg ctttgaatat
    24601 caatattctc tttgcggcaa tggtcgagaa taaactgtcc tgcggcatct ttaccaatac
    24661 ggc
//
LOCUS       DAPHKZ010000064        23938 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.064, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000064 DAPHKZ010000000
VERSION     DAPHKZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23938
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.064"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(332..1243)
                     /gene="gsiD"
                     /locus_tag="RH288_002696"
     CDS             complement(332..1243)
                     /gene="gsiD"
                     /locus_tag="RH288_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HDV4031739.1"
                     /translation="MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAA
                     LFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTVLLRHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPA
                     LAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(1246..2166)
                     /gene="gsiC"
                     /locus_tag="RH288_002697"
     CDS             complement(1246..2166)
                     /gene="gsiC"
                     /locus_tag="RH288_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HDV4031740.1"
                     /translation="MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEAD
                     AQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLT
                     ITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELG
                     WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQA
                     EILLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            complement(2184..3722)
                     /gene="gsiB"
                     /locus_tag="RH288_002698"
     CDS             complement(2184..3722)
                     /gene="gsiB"
                     /locus_tag="RH288_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HDV4031741.1"
                     /translation="MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGITYTVKLREGIKFQDGT
                     DFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
                     PATAMISPAALEKYGKEIGFYPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSI
                     TWRPVADNNTRAAMLQTGEAQFAFPIPYEQATLLEKNKNIELMASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKA
                     RELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQ
                     ALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFED
                     ADLQ"
     gene            complement(3742..5613)
                     /gene="gsiA"
                     /locus_tag="RH288_002699"
     CDS             complement(3742..5613)
                     /gene="gsiA"
                     /locus_tag="RH288_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HDV4031742.1"
                     /translation="MPHSDELDAGNVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGET
                     LAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLQRRSREVIELSEQNAAQMRHVR
                     GADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEM
                     SMGVIFITHDMGVVAEIADRVLVMYQGEAVETGTVEQIFHAPQHPYTRALLAAVPQLG
                     AMKGLDYPRRFPLISLEHPAKQAPPIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVT
                     REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLS
                     PGKLQALRRDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKDAAARVAWLLERV
                     GLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD
                     LQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAA
                     VPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR"
     gene            complement(5600..6565)
                     /gene="iaaA"
                     /locus_tag="RH288_002700"
     CDS             complement(5600..6565)
                     /gene="iaaA"
                     /locus_tag="RH288_002700"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDV4031743.1"
                     /translation="MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLE
                     AGESALDVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACVMDGNTLKAGAVAGVSH
                     LRNPVLAARLVMEQSPHVMMIGEGAENFAFARGMERVSPEIFSTPLRYEQLLAARKEG
                     ATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGG
                     LIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ"
     gene            6769..8004
                     /gene="moeA"
                     /locus_tag="RH288_002701"
     CDS             6769..8004
                     /gene="moeA"
                     /locus_tag="RH288_002701"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDV4031744.1"
                     /translation="MEFTTGLMSLNTALNEMLSRVTPLTAQETLPLVQCFGRILASDV
                     VSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGA
                     PVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAE
                     LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGC
                     EVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVR
                     TASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGN
                     VEVGEWVEVEPFNALFGGL"
     gene            8004..8753
                     /gene="moeB"
                     /locus_tag="RH288_002702"
     CDS             8004..8753
                     /gene="moeB"
                     /locus_tag="RH288_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HDV4031745.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGC
                     AASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIA
                     ITPVNALLDDAELAALIAEHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
                     ITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKMLAGYGKP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(8829..9491)
                     /gene="fsa"
                     /locus_tag="RH288_002703"
     CDS             complement(8829..9491)
                     /gene="fsa"
                     /locus_tag="RH288_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDV4031746.1"
                     /translation="MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLDVVLP
                     QLHEAMGGQGRLFAQVMATTAEGMVNDALKLRSIIADIVVKVPVTAEGLAAIKMLKAE
                     GIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQA
                     KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRT
                     SI"
     gene            9622..10521
                     /locus_tag="RH288_002704"
     CDS             9622..10521
                     /locus_tag="RH288_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415345.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDV4031747.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDL
                     LYDARLCLEGCELCAKAAPEVIERALNGLLIHREKLTPEHLTALTDCCPTQALTVCGE
                     VKSVEEIMTTVLRDKPFYDRSGGGLTLSGGEPFMQPEMAMALLQASHEAGIHTAVETC
                     LHVPWKYIAPSLPYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIR
                     VPLIQGFNADETSVKAITDFAADELHVGEIHFLPYHTLGINKYHLLNLPYDAPEKPLD
                     APELLDFAQQYACQKGLTATLRG"
     gene            10527..12959
                     /locus_tag="RH288_002705"
     CDS             10527..12959
                     /locus_tag="RH288_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDV4031748.1"
                     /translation="MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDGLREKVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSE
                     HIERFAALAREMAATETRESRRDELLAMAENCDLIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDT
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQK
                     LMILLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            13105..13920
                     /gene="ybiV"
                     /locus_tag="RH288_002706"
     CDS             13105..13920
                     /gene="ybiV"
                     /locus_tag="RH288_002706"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase YbiV"
                     /protein_id="HDV4031749.1"
                     /translation="MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIKFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPL
                     VIDKLHVALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGN
                     DAEMLKMARYSFAMGNAAENIKQIARYATDDNNHEGALNVIQAVLDNTSPFNS"
     gene            14072..15337
                     /locus_tag="RH288_002707"
     CDS             14072..15337
                     /locus_tag="RH288_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1479 domain-containing protein"
                     /protein_id="HDV4031750.1"
                     /translation="MASTFTSDTLPADHKAAIRQMKHALRAQLGDVQQIFNQLSDDIA
                     TRVAEINALKAQGDAVWPVLSYADIKAGHVTAEQREQIKRRGCAVIKGHFPREQALGW
                     DQSMLDYLDRNRFDEVYKGPGDNFFGTLSASRPEIYPIYWSQAQMQARQSEEMANAQS
                     FLNRLWTFESDGKQWFNPDVSVIYPDRIRRRPPGTTSKGLGAHTDSGALERWLLPAYQ
                     RVFANVFNGNLAQYDPWHAAHRTEVEEYTVDNTTKCSVFRTFQGWTALSDMLPGQGLL
                     HVVPIPEAMAYVLLRPLLDDVPEDELCGVAPGRVLPVSEQWHPLLIEALTSIPKLEAG
                     DSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYAHKVKAALEKGASPGDFP
                     REDYETNWEGRFTLADLNIHGKRALGMDV"
     gene            complement(15578..17170)
                     /locus_tag="RH288_002708"
     CDS             complement(15578..17170)
                     /locus_tag="RH288_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HDV4031751.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
                     KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPL
                     FKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEI
                     TPERVIDFSGNYEDYLRSKGIE"
     gene            17389..18309
                     /gene="ldtB"
                     /locus_tag="RH288_002709"
     CDS             17389..18309
                     /gene="ldtB"
                     /locus_tag="RH288_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDV4031752.1"
                     /translation="MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVIT
                     IPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIV
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDI
                     KFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKS
                     VQTVTGQPDVDQVVLDEAIKNRSGMPVRLN"
     gene            complement(18368..19486)
                     /locus_tag="RH288_002710"
     CDS             complement(18368..19486)
                     /locus_tag="RH288_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HDV4031753.1"
                     /translation="MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVAL
                     FIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFI
                     AQMAPLAGAMMLTLLLLCWCCFPGKAMQYHTGVQTPEWKPRLVWSCLGLYIVFLTALE
                     FKQELWGLVIVAAGFALLARRVVLSVDWTLLLVFMAMFIDVHLLTQLPALQGVLGNVS
                     HLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLVWAVNVGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHLYSIPMLFWAALVGYVLLVILPAN"
     gene            complement(19483..19950)
                     /gene="mntR"
                     /locus_tag="RH288_002711"
     CDS             complement(19483..19950)
                     /gene="mntR"
                     /locus_tag="RH288_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HDV4031754.1"
                     /translation="MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK"
     gene            20136..20264
                     /gene="mntS"
                     /locus_tag="RH288_002712"
     CDS             20136..20264
                     /gene="mntS"
                     /locus_tag="RH288_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HDV4031755.1"
                     /translation="MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK"
     gene            20536..22119
                     /gene="opgE"
                     /locus_tag="RH288_002713"
     CDS             20536..22119
                     /gene="opgE"
                     /locus_tag="RH288_002713"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDV4031756.1"
                     /translation="MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTA
                     AFTAILLLLWRTLPRVQKVLVGVSSLVAACYFPFAQAYGAPNFNTLLALHSTNMEEST
                     EILTIFPWYSYLVGLFIFALGVIAIRRKKENEKARWNTFDSLCLVFSVATFFVAPVQN
                     LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQT
                     YVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVD
                     GKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADK
                     NTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLY
                     TMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVP
                     FMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGPIYITNF
                     QLQKVDYNHLGTDIFDPKP"
     gene            complement(22168..22683)
                     /gene="ompX"
                     /locus_tag="RH288_002714"
     CDS             complement(22168..22683)
                     /gene="ompX"
                     /locus_tag="RH288_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HDV4031757.1"
                     /translation="MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKM
                     GGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASI
                     YGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
     gene            complement(22736..22801)
                     /locus_tag="RH288_002715"
     CDS             complement(22736..22801)
                     /locus_tag="RH288_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031758.1"
                     /translation="METFCYMKWPVRHHKSRRVSH"
     gene            23036..23923
                     /gene="rhtA"
                     /locus_tag="RH288_002716"
     CDS             23036..23923
                     /gene="rhtA"
                     /locus_tag="RH288_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HDV4031759.1"
                     /translation="MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVT
                     ALRLALGTLILTAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
                     AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAAS
                     MGSTLTVRKESKIKELDIN"
BASE COUNT         5853 a         6512 c         5964 g         5609 t
ORIGIN      
        1 tctgaataag ttcaaagcgg ctatcggcac gttttaccgc gcgctccgat accagttgat
       61 agttaatgat gaaaaaaaga ccaataaatg acagtgctgc caataaaaat aaaattatca
      121 gccttatctt tatcttttcg tataaactca gcatgttaat acatttaaca aaataactat
      181 ctgaacgctg tgccgctgca aaaattgtcc cttgctgcgg ctttttaacc aaattacccg
      241 attctacaaa atcagcagaa agttacaaca cttgcttagg gcaataattt cctgtgaggt
      301 gattaccctt tcaagcaata ttcaaacgta actatccttt aattttcgga tccagcgcat
      361 cgcgtaaacc atcgcccaac aaattgaacg ccagtacggt cagaaaaata gccagggccg
      421 gaaaaacagc gacatgcggc gcgataacca tatccgctcg agcctcattg agcattgctc
      481 cccactctgg tgtcggcggc tgcgcaccga ggccgagaaa tgagaggctg gcggcagaga
      541 taatcgaggt accaatgcgc atggtgaaaa acaccacgat agaagagacg gtaccaggca
      601 ggatatgacg caacaaaacg gtcatatcgc tggcaccaat actgcgtgct gactcaataa
      661 aggtttgctg tttcaacacc agcgtgttgc cgcgcaccag gcgggcaaac gcggggatgg
      721 aaaaaatggc gactgcaata atcacgttag caatgccgct tcccaacacc gcaacaacag
      781 cgatcgccag taaaataccc gggaaggcaa acagcacatc gcaaatgcgc atgatcagcc
      841 gatcccacca gccttcataa tatccagcga gcaagcccag caacgtcccg atcgccgcac
      901 cgataaacac ggcaaacacg cccgccgcca gcgagatttg cgcaccaacc aggacacggc
      961 tgaaaatgtc acgccccagt gaatcgacgc caaaccagtg ctgcaaagaa ggtccgttat
     1021 tcagattgtc ataatcaaaa taattttcgg cgtcataggg agcgatccag cgtgcaaaaa
     1081 tggccaccac aatcaataaa ataacgaata atgcggcggt catcgccata tgctgacggc
     1141 gaaatcgtcg ccagaattca tgccacggtg tacgtacctg gtcaggtttg accagtggca
     1201 tggcgtttaa caccgcctga cgtcgccagt taaatagtcg catccttact tgtacctgat
     1261 agccgggtta atggcggcgt aaagcacatc caccactaag ttgataagaa taaattccag
     1321 cgagaaaagc agaatttccg cctgaatcac cgggtaatca cgcatttcta cggagtcaac
     1381 gagtaagcgt ccaagtcccg gccagttgaa aactttctcc acaacgatgg aaccaccgag
     1441 caaaaagcca aactgtaagc ccatcatggt cactaccggg atcatcgcgt tacgtagccc
     1501 gtgtttgagg acaacccagg tttcgctcac ccctttcgcc ctcgcggtac gcatataatc
     1561 ttcgcttaaa acatcgacaa acgacgcgcg ggtaaagcgc gccatcacgg cggccactgc
     1621 cgcgccgagc gtcagggagg gtaaaatgta gtgctgccaa ctgtctgctc ccacggtagg
     1681 cagccagccc agttcaacgg agaatacctg aattaaaagc atccccagag caaatgccgg
     1741 aaacgagatc cccgacaccg caatggtcat actcaatcga tccggccaac ggttacgcca
     1801 gacggcggcg ataattcccg ccgccatacc aaatataacc gcccagacca tactggttat
     1861 ggtcagccac agcgttggca taaagcggct ggcaatctca tcggcaaccg gacgacgcga
     1921 caccatcgac aggccaaaat ccccctgcac agcattgctg atatagtgcc agaactggtg
     1981 atacagcggc tgatccaacc ccagctgctg acgcaccagt tctataacct gcgcatcagc
     2041 ttcgggcccg gcaatcaatc gcgccggatc gccgggcagc atatggacaa ataaaaacac
     2101 cagcaccgag acgataaaca gcgtcggaat caaccccagt aagcgtttga taacgtaatt
     2161 aagcattcca ctccctgcgt tgcttattgc aaatccgcgt cttcaaagct gaagccggtg
     2221 tctggcatga tccaaaaacc ggtcaggttt ttactgtgtg ccgacaccag tttttctacc
     2281 accagcggga tccacggcga ttcttgccag atgatatcct gcgccgcctt atataagcgg
     2341 gtcttttccg ccggatcatt agttttcagt gcctgagcca ggaagtcatc cacctgttta
     2401 ttgctgtaaa acgcggtatt aaacagcgtc ggtggccagt tctgcgaggc aaacagcggc
     2461 gatagtgccc agtccgcttc gccggttgaa gccgaccagc cagtgtagaa catccgcacg
     2521 ccgctctctt tttgcccttt accttcaact tctgccgccc gctgtccggc atccatcgca
     2581 gtcacctggg ctttaatccc gacctgcgct aactgctgct gggtaaattg cagcactttc
     2641 tgcgcggtgc tgtggttatg tgacgaccac agcgtggtac tgaaaccgtt gggatatccc
     2701 gcctctttca gtaattcgcg cgctttcact ggatcgtaag gccacggttt ataactttgc
     2761 gcgtaggcga tacttggcgg taccacacca gtagctggcg ttgcatagcc cgcaaaggca
     2821 actttcacca gcgccggacg gttaatggcg taattcagcg cctcacggac cttcgggtta
     2881 tcgaacggct tttgcgtcac gttcatactg atataacgct gcataattga cggactggcc
     2941 atcaactcga tatttttgtt tttctccagc agtgtggcct gctcgtaagg aatggggaaa
     3001 gcaaactgcg cttcaccggt ttgcagcatt gccgcgcggg tgttgttatc cgccaccgga
     3061 cgccaggtta tgctgtccag tttgggcaat cctggctgcc agtaacccgc gaattttttc
     3121 accttcacaa aatcggtctg attccaggta tccagttcat acggtccggt tcccaccgga
     3181 taaaaaccaa tctccttgcc atatttttcc agcgctgccg gtgaaatcat cgcggtcgcc
     3241 ggatgggcaa gaatattaat aaacgctgag aacggctgtt tgagggtaat ctttaccgtt
     3301 gtcggatcga tcgcttccgt tttagcaata ttcttataca ggttatagcg tttaagatga
     3361 ttcgccggat cgctggcccg gtccagattc gctttcaccg ccgcggcgtt gaaatcggtg
     3421 ccatcctgga atttaatgcc ttcccgcaat ttcacggtgt aagtaatgcc gtcatcggaa
     3481 acggtataac tctccgccag cacgtttttc agtttcatct ctttatccag accgaacagc
     3541 ccctggtaaa acgatttcgc tacggcctga gataacgtgt catttgcgtc atacggatcg
     3601 agcgtggtga aattcgatcc taccgccacc accacatctt tggcagcgaa tgcacaagat
     3661 gccatcaacg ctgtcgcaat gcccagcgcc actaacccac tacggtgtac agctcttgcc
     3721 attttattct ccgcctgaat gttatctacg catgaatgcg tattctgatt gtggttgtgc
     3781 gacgtaatgc cccggcccga cgcattgcaa cgagacggct gccacctctt cgccacgcag
     3841 atgaatattg ctgggaagat cgtccgacag cagtacacgc tgcggtcgtt gtcgggacgg
     3901 ttcagcgacc ggaactgccg ccagtaattt acgcgtataa ggatgctgcg ggttttcgaa
     3961 gaccgcgcgc cgtggaccaa tttcaacaat ttgcccgaga tacatcaccg ccacacgatg
     4021 actaatccgc tctaccaccg ccatatcgtg ggagataaac agatacgcaa tgccgaaatc
     4081 acgctggaga tcgagcaaca agttgataat ctgcccgcga atagaaacat ccagcgccga
     4141 aacggcttcg tcggcaatga tcacttttgg attcaatgcc aacgcgcgag caatgcagat
     4201 gcgctggcgc tgaccgccgg aaaactcatg cgggtaacgc caggcatgtt caggtaacag
     4261 gcccacgcgc tccagcaacc acgcaacgcg tgcagccgcg tctttacctg gcaataaacc
     4321 gtgtacacgc agcggttcga taatcgaatc accgatggtc tgacgtgggt ccagcgaagc
     4381 gtaagggtcc tgaaaaataa actgaatatc ccggcgtaat gcctgaagtt tgccgggtga
     4441 caaggtatcg attcgctgac cgttaaagat aatttcgccg ccctgcgatt cgaccaggcg
     4501 cagcaacgcc cgcccggtag tggatttacc gctgccagac tcgcccacca gcgatagcgt
     4561 ttcgccaggc cagagatcaa aactgacttt ctcaacggca tgcacttccc gcgttacgcg
     4621 attcaacaaa ccgctgcgca aagggaaacg ggtgacaaga ttacgcactc gtaaaacagg
     4681 ttcgccatcc accaccgttt tctgctcgat ggggggggcc tgtttcgctg gatgttcaag
     4741 cgatatcaac gggaaacgtc ggggataatc taaccctttc atcgcaccaa gttgcggaac
     4801 agcagctaac agcgcacggg tgtaaggatg ttgcggtgca tgaaaaatct gttcgacggt
     4861 acccgtttcc accgcctcgc cctgatacat caccagtacc cgatcggcaa tctctgccac
     4921 cacgcccata tcgtgagtga taaagataac gcccatcgac atctcttttt gcaatacttt
     4981 gattaattgc aggatctgcg cctgaatagt gacatccagc gcggtggttg gctcatcggc
     5041 aatcagcacc gccgggcggc atgacagcgc catcgcaatc atcactcgct ggcgcatccc
     5101 gccagagagt tgatgcggat aacgtgaaag aatggtttgt gcctcaggaa tgcgtacctg
     5161 atccagcatc cgcttcgcct cgaccatcgc ttcttcacga ctggcgttct gatgcagacg
     5221 aattgattcg gcaatctgtt cacccacagt aaataccggg ttcagcgatg tcatcggctc
     5281 ctgaaatatc atcgccatat ccgcaccgcg aacatggcgc atttgtgcag cgttctgctc
     5341 gctaagttca atcacttcgc gactgcgccg ctgcaacagc attttatcgc actgtactaa
     5401 accgcccgcc tgttccaaca ggcgcatcaa tgccaacgca gtcactgact taccggagcc
     5461 ggattcgcca acaattgcca gcgtctcacc gcgttgcaga ctaaaagaga gattgcggac
     5521 cgcagctatt ttctgctggt cctgcataaa ggcaatattc agattttcaa ccgccagcac
     5581 attaccggca tcaagttcat cactgtgtgg caacggtgtc ccctttttca cggtagatac
     5641 cggtggttgg cgtatcgcct gcgtagcccc aggcgcgata cattccttcg gtgttaaacg
     5701 gtagcgcgac attcccttca tggtcgatag cgattaagcc accgctaccg ccaagcgcag
     5761 ggagtttttc cattactacc cgctcgcagg cttccgcgag acttaatccg ccgtaatcca
     5821 ttaacgcggc gatgtcatat gccgccagcg cgcggatgaa gacttcgccc gtgccggtac
     5881 aagaaaccgc cacactggcg ttattggcgt agcatccggc acccactaag ggactatcgc
     5941 caactcgtcc gggtaattta ttggtcattc cgcctgtgga cgtggctgcc gccaaattgc
     6001 cgtctaaatc caacgccacg gcccccacgg tgcccatttt ctgtttttca tccagtggcg
     6061 caccgctatg gtcgaggacg gttgcccctt ccttgcgcgc tgccagtagt tgttcataac
     6121 gcaaaggcgt ggagaaaatc tccggcgaga cgcgctccat gccacgagca aacgcaaaat
     6181 tttctgcccc ttcgccaatc atcatcacat gcgggctttg ctccatcacc agccgggcgg
     6241 caagaaccgg attacgcaga tgactaacgc ccgccaccgc accggctttc agggtgttac
     6301 catccatcac acaggcgtcc agttcatggg tttcatcacg cgtaaagaca gcgccaattc
     6361 cggcgttaaa cagtggacac tcttccagca gacgcaccgc ttccgtcacc acatccagcg
     6421 cactttcgcc cgcttccagc attttctgcc cggtttcaac aatggcagac aacgcctcga
     6481 tgtagcgtaa ttcctgttgc agactcatct gcgcgcggct aattgcacct gcgccaccat
     6541 gaattgcaat gactgctttg cccatagtat tcgtccatta agggtggttc gccacttttg
     6601 ctataaatat cagaattttt atgaattact cattcaattt ttgaatatag aaagatggat
     6661 atggcatgta aaggcaggac ccagcgctac gcccgaggtg gcatacagtc tgtggcgttt
     6721 ttctgacata ataggcaaat tcgattttgc ctccgcagga gtgttttcat ggaatttacc
     6781 accggattga tgtcgctcaa caccgcgctt aatgagatgc tttctcgcgt caccccactg
     6841 accgcccagg aaacgctgcc actggtacag tgttttggtc gtattctggc gagcgatgtc
     6901 gtttcgccgc ttgatgttcc ggggtttgat aactccgcaa tggacggcta cgcggtgcgt
     6961 ttagccgata ttgcctccgg gcaaccgctg cccgttgccg gtaaatcctt tgccggtcag
     7021 ccataccatg gtgaatggcc tgcgggtacc tgcattcgta ttatgaccgg tgcgccggtg
     7081 ccggaaggct gcgaagcggt ggtgatgcag gagcagactg aacaaatgga caatggcgtg
     7141 cgttttactg ctgaagtgcg tagcgggcaa aatattcgcc gtcgcggtga agatatctct
     7201 gcaggtgcgg ttgttttccc ggcgggaact cgcctgacta ccgcagagct gccagtaatt
     7261 gcttcactgg ggattgccga agttccggtg attcgtaaag tgcgtgtagc gcttttttct
     7321 accggtgatg aactccagtt gcccggtcag ccgctgggcg acggccaaat ctacgatacc
     7381 aaccgtctcg ccgtacacct gatgttagaa cagttgggat gcgaggtaat taacttaggg
     7441 attatccgcg acgatcccca tgccctgcgc gccgcattta ttgaagccga cagccaggcg
     7501 gatgtggtga tcagttccgg cggtgtttca gtgggtgagg cggattacac caaaacgatt
     7561 cttgaagagc tgggggagat cgccttctgg aagctggcga ttaaaccagg taaaccgttc
     7621 gcgttcggta aactcagcaa tagctggttc tgcggcctgc cgggcaaccc ggtttcagcg
     7681 acgctgacct tctatcaact ggtacagcct ttgctggcaa aactaagcgg taacaccgcc
     7741 agcggcctgc ccgcgcgcca gcgcgtacgc acagcgtccc gcctgaaaaa aacgccagga
     7801 cgtcttgatt tccagcgcgg cgtgctgcaa cgcaacgccg atggcgaact ggaagtgacg
     7861 accaccggac atcagggttc acatatattt agctccttta gcctcggcaa ctgctttatc
     7921 gtgctggaac gcgatcgcgg caatgtggaa gtgggcgaat gggtggaagt agaaccgttt
     7981 aacgcgttgt tcggaggcct gtaatggcgg aactcagcga tcaggagatg ctgcgctaca
     8041 accgacaaat cattctgcgc ggctttgatt ttgacggcca ggaggcgctg aaagattctc
     8101 gcgtgctgat agtgggcctg ggcggcctcg gctgtgcagc ctcgcagtat ctggcaagcg
     8161 ccggtgtcgg taacctgacg ctgctcgact tcgacacggt ttcgctctcg aatctgcaac
     8221 gccagacact gcacagtgat gccacggtcg ggcaaccgaa ggtggaatcc gcccgtgacg
     8281 ccctgacgcg gatcaaccca catatcgcga ttacgccagt caatgcactg ctggatgacg
     8341 cagaacttgc agcattgatt gctgaacacg atctggtgct cgactgtacg gataacgttg
     8401 cggtacgtaa tcaactgaac gcaggctgtt ttgccgcgaa ggtaccgctg gtttccggcg
     8461 cggcaattcg tatggaaggt caaatcaccg tctttactta tcaggacggt gaaccgtgct
     8521 atcgctgcct tagccgtttg tttggtgaaa atgcattaac ctgcgtggaa gcaggcgtaa
     8581 tggcaccgtt gatcggcgta attggttcgt tgcaggcaat ggaagcgatc aaaatgctgg
     8641 caggttatgg caaaccggcc agcgggaaaa tcgtcatgta cgatgcgatg acctgtcagt
     8701 ttcgcgaaat gaaactgatg cgtaatccgg ggtgtgaggt gtgtgggcag taattgccac
     8761 ctccaggcct gataagacgc ggcactccgc cacgtcatca gcaatttatg aggatgcaga
     8821 acgtccggtt aaatcgacgt tctgccaaac gctccctgcc agtcctgctc aaacttcgcc
     8881 acagcggcat caaccgccgg atagctaatc atctgttgtg ccacatccag tggcagagta
     8941 attgattcac atcctgccag taagcagtcc agcgcctgac gcggggtttt gaaactcgct
     9001 gccagcactt tcgcctgcgg cgcatgcatt ttcaataact ggtgtaagtc ggtcacagtc
     9061 tgaatgccgc taccgccctg agcatcaata cgattaacgt aaggcgcaac atattccgca
     9121 cctgccagcg ccgacagcag cccttgtgct gcgccatata ccgcggttcc cagcgtcgga
     9181 atcccttccg cttttaacat cttaatagct gccagcccct cggcggtcac cggaactttc
     9241 accacgatat ccgcaataat agaacgcagc ttaagcgcgt cattaaccat cccttcggca
     9301 gtggtagcca ttacctgggc aaacagacgc ccctgaccgc ccatcgcttc atgaagttgc
     9361 ggaagcacaa catccagcgg ttttttaccc gcggcgataa tgcttgggtt agtggtcaca
     9421 cccgccagcg gaaaaatacg tgacagcgcc ttcaccgcaa caacgtctga agtatccaga
     9481 tacagttcca taaccatcct caaaatgtac tttttgtctg aatgtagact atcacgggaa
     9541 aactctctga acagttgacg cacatcaatc taactttcat tcgaaagtat tttaatgctt
     9601 gaacgaaata tagaggcaac tatgattttc aatattcagc gctactcgac ccatgatggc
     9661 cccggtatcc gcacggtcgt atttcttaaa ggctgttcgc tgggctgccg ctggtgtcag
     9721 aacccggaaa gccgcgcccg cacgcaggat ctgctgtatg acgcacgact gtgtctggaa
     9781 ggctgcgagc tgtgcgctaa ggccgcgccg gaagtgattg agcgcgcgct gaatggtttg
     9841 cttattcatc gggaaaagtt aaccccggag catctgacgg cgttaaccga ctgctgtccg
     9901 acacaggcat taaccgtgtg tggtgaagtg aaaagcgttg aggagatcat gacgaccgtt
     9961 ctgcgcgata aaccgtttta cgatcgcagc ggcggcggtt taacgctttc gggtggtgag
    10021 ccctttatgc agccggaaat ggcgatggcg ctactgcaag ccagccacga ggcaggcatt
    10081 catactgcgg tagaaacctg tctgcatgtg ccgtggaaat atatcgcccc ttctctgccc
    10141 tatatcgatc tgtttcttgc cgatttaaaa cacgttgccg acgcgccgtt taaacagtgg
    10201 accgacggta acgccgccag agtgctggat aacctgaaaa aactcgccgc agcgggcaaa
    10261 aaaatcatta tccgcgtgcc gctgattcag ggctttaatg ccgacgaaac ctctgtaaaa
    10321 gccattaccg attttgccgc cgacgagctg cacgttggcg aaattcattt tctgccctac
    10381 cacacgctgg gcatcaacaa atatcactta cttaatctgc cctatgacgc cccggaaaaa
    10441 ccgcttgatg cgccagaact gctcgacttt gcccagcagt atgcctgcca gaaagggtta
    10501 accgcgacct tacgaggata acaaccatga ccacactgaa actggacacg ctcagcgacc
    10561 gcattaaagc gcacaaaaat gcgctggtgc atattgtgaa accgccagtc tgtaccgagc
    10621 gcgcgcagca ctataccgag atgtatcaac aacatctcga taagccgatc ccggtacgtc
    10681 gcgcgctggc actggcgcat cacctggcga atcgcaccat ctggatcaaa cacgatgagt
    10741 tgatcattgg caaccaggca agcgaagttc gcgccgcgcc gatcttcccg gaatatactg
    10801 tctcgtggat cgaaaaagag attgatgatc tggcagatcg tcccggtgct ggctttgcgg
    10861 tgagcgaaga gaacaaacgc gttctgcatg aagtgtgccc gtggtggcgc ggtcagaccg
    10921 tacaggatcg ctgctacggc atgtttaccg atgagcaaaa aggtctgctg gcgaccggaa
    10981 tcattaaagc ggaaggcaat atgacctccg gcgatgcgca cctggcggtg aatttcccgc
    11041 tgctgctgga aaaagggctt gatggtctgc gcgagaaagt agcggaacgt cgctcgcgca
    11101 tcaacctgac ggtgctggaa gatttacacg gtgagcaatt cctgaaagcg attgatatcg
    11161 tgctggtggc agtcagtgaa cacattgaac gtttcgctgc cctggcgcgt gaaatggccg
    11221 cgaccgaaac ccgcgaaagc cgtcgcgatg aactgctggc gatggcagaa aactgcgatc
    11281 ttatcgccca ccagccgccg cagactttct ggcaggcgct gcaactgtgt tacttcatcc
    11341 agttgatttt gcagatcgaa tctaacggtc actcagtatc gtttggtcgt atggaccagt
    11401 atctctaccc gtactatcgc cgcgacgttg aactcaacca gacgctggat cgcgaacacg
    11461 ccatcgagat gctgcatagc tgctggctga aactgctgga agtgaacaag atccgctccg
    11521 gctcacactc aaaagcctct gcgggaagtc cgctgtatca gaacgtcact attggcgggc
    11581 aaaatctggt tgatggtcaa ccaatggacg cggtgaatcc actctcttac gcgatcctcg
    11641 aatcctgcgg tcgcctgcgt tccactcagc ctaacctcag cgtgcgttac catgcaggaa
    11701 tgagcaacga tttcctcgac gcctgcgtac aggtgatccg ttgcggcttc gggatgccgg
    11761 cgttcaacaa cgacgaaatc gtgatcccgg aatttattaa actcggtatt gaaccgcagg
    11821 acgcttatga ctacgcagcg attggttgta tagaaaccgc cgtcggtggc aaatggggct
    11881 atcgctgtac cggcatgagc tttatcaact tcgcccgcgt gatgctggcg gcgctggaag
    11941 gcgggcatga tgccaccagc ggcaaagtgt tcctgccaca agaaaaagcg ttgtcggcag
    12001 gtaacttcaa caacttcgat gaagtgatgg acgcgtggga tacgcaaatc cgttactaca
    12061 cccgcaaatc aatcgaaatc gaatatgtcg tcgacaccat gctggaagag aacgtgcacg
    12121 atattctctg ctcggcgctg gtggatgact gtattgagcg agcgaaaagt atcaagcaag
    12181 gcggcgcgaa atatgactgg gtttctggcc tgcaggtcgg cattgccaac ctcggcaaca
    12241 gcctggcggc agtgaagaaa ctggtgtttg aacaaggtgc gattggtcag caacagcttg
    12301 ctgccgcact ggcagatgac ttcgacggcc tgactcacga gcagctgcgt cagcggctga
    12361 ttaacggtgc gccgaagtac ggcaacgacg atgatactgt cgatacgctg ctggctcgcg
    12421 cttatcagac ctatatcgac gaactgaaac agtaccataa tccgcgctac ggtcgtggtc
    12481 cggttggcgg caactattac gcgggtacgt catcaatctc cgctaacgta ccgtttggcg
    12541 cgcagactat ggcaacaccg gacgggcgta aagcccacac cccgctggca gaaggcgcaa
    12601 gcccggcctc cggtactgac catcttggcc ctactgcggt cattggctca gtgggtaaac
    12661 tgcctacggc agcgattctc ggcggcgtgt tgctcaacca gaaactgaat ccggcaacgc
    12721 tggagaacga atctgacaag cagaaactga tgatcctgct gcgtaccttc tttgaagtgc
    12781 ataaaggctg gcatattcag tacaacatcg tttcccgcga aacgctgctg gatgcgaaaa
    12841 aacatcccga tcagtatcgc gatctggtag tgcgtgtcgc gggctattcc gcgttcttca
    12901 ccgcgctctc tccagacgct caggacgata tcatcgcccg tactgaacat atgctgtaat
    12961 ctcctcggcc cggcggcgtc gtcgccgggc taaatcattc acatcatcaa tttcatcctt
    13021 actttcattc gaaatataat ttgtgctctg cgtcacattg ttattacact gttacggttt
    13081 cattttcgag ccaggagcac acctatgagc gtaaaagtta tcgtcacaga catggacggt
    13141 acttttctta acgacgccaa aacgtacaac caaccacgtt ttatggcgca atatcaggaa
    13201 ctgaaaaagc gcggcattaa gttcgttgtt gccagcggta atcagtatta ccagcttatt
    13261 tcattctttc ctgagctaaa ggatgagatc tcttttgtcg cggaaaacgg cgcactggtt
    13321 tacgaacatg gcaagcagtt gttccacggc gaactgaccc gacatgaatc gcggattgtt
    13381 attggcgagt tgctaaaaga taagcaactc aattttgtcg cctgcggtct gcaaagtgca
    13441 tatgtcagcg aaaatgcccc cgaagcattt gtcgcactga tggcaaaaca ctaccatcgc
    13501 ctgaaacctg taaaagatta tcaggagatt gacgacgtac tgttcaagtt ttcgctcaac
    13561 ctgccggatg aacaaatccc gttagtgatc gacaaactgc acgtagcgct cgatggcatt
    13621 atgaaacccg ttaccagtgg ttttggcttt atcgacctga ttattcccgg tctacataaa
    13681 gcaaacggta tttcgcggtt actgaaacgc tgggatctgt caccgcaaaa tgtggtagcg
    13741 attggcgaca gcggtaacga tgcggagatg ctgaaaatgg cgcgttattc ctttgcgatg
    13801 ggcaatgctg cggaaaacat taaacaaatc gcccgttacg ctaccgatga taataatcat
    13861 gaaggcgcgc tgaatgtgat tcaggcggtg ctggataaca catccccttt taacagctga
    13921 cctctctacc ggagccgtgc gctccggttt tcccttcttt ttacatcctg tacatcacat
    13981 caaatcatta aacttgcatt aacttattta taacttatat tgtcacatgc aaatcagaat
    14041 ggtttcgaat gaaagttaat gagaggtggt tatggcttct acttttacca gcgacacatt
    14101 gcctgccgat cacaaagcag ctatccgtca gatgaagcac gcgctgcggg cgcagcttgg
    14161 cgacgtccag cagatcttta atcagctaag cgatgacatt gccacgcgag tggctgaaat
    14221 caacgcactc aaagcacagg gcgatgccgt ctggccggtg ctgtcttatg ccgatatcaa
    14281 agcaggtcat gttactgcag agcagcgcga acagattaaa cgtcgcggtt gtgcggtgat
    14341 aaaaggccat ttcccccgcg aacaagcgct aggctgggat cagtcgatgc tggactatct
    14401 ggaccgcaac cgctttgacg aggtctacaa aggccccggc gataatttct tcgggacgct
    14461 cagcgcttca cgtcccgaga tttaccccat ctactggtcg caggcgcaaa tgcaggcccg
    14521 ccagagtgaa gaaatggcga atgcgcagtc gtttctcaat cgtctgtgga catttgaaag
    14581 tgatggaaag caatggttta acccggatgt gagcgtcatc taccctgacc gtatccgccg
    14641 ccgtccgccc ggaacgacct ccaaaggtct tggagcgcat accgactccg gggcactgga
    14701 acgctggctg cttccagcgt atcagcgcgt tttcgccaac gtctttaatg gcaatctggc
    14761 gcaatatgat ccctggcatg cggcacatcg tacggaagtt gaagagtaca cggtggacaa
    14821 caccaccaaa tgttccgtgt ttcggacatt ccagggctgg acagcgctct ctgatatgct
    14881 gcctggtcag gggctgctgc acgtcgtgcc cattcctgaa gctatggcgt acgtactgtt
    14941 acgtccgctg cttgatgatg tgccggagga tgaactgtgc ggcgtagcgc ccggaagagt
    15001 attgccggta tcagagcaat ggcatccact gttgattgag gcgttaacca gcattccaaa
    15061 actcgaagcc ggagactccg tctggtggca ctgcgacgtc atccattccg ttgcccccgt
    15121 tgaaaatcaa caaggttggg gcaacgtgat gtacattcct gcggcaccga tgtgcgagaa
    15181 aaatcttgcc tacgcgcaca aggtgaaggc cgcactggaa aaaggcgcat cgccgggcga
    15241 cttcccgcgc gaggactatg aaacaaactg ggaaggacgc tttacgcttg ccgacctcaa
    15301 cattcacggt aagcgagcgt tgggcatgga tgtttgagaa ttaatggaag tgaattgatg
    15361 tgggattaag aaaatcgatt cgacgttact cagattgctg acaaatgcgc tttgttaatg
    15421 cctgatgcgg cgttaacgcc ttatccggcc tacaaagtcc tgcagattca atatattgca
    15481 ggtactgcgt aggcctgata agcgtagcgc atcaggctat tttgcatttg tcatcagccg
    15541 ccgtcacccc gacagtatcg gggtgacgga taatcactta ctcgatccct ttactacgca
    15601 ggtaatcttc gtaattaccg ctaaagtcga tcacgcgttc cggggtgatt tccagaatgc
    15661 gggtcgccag ggagcttacg aactcacggt cgtgtgaaac aaagatcagc gtgccctgat
    15721 acagttccag tgccatgttc agcgactcaa tggattccat atccaggtgg ttggtcggtt
    15781 cgtccatgat cagaatgttc ggcttctgca tcattaactt accaaacagc atccgccctt
    15841 tttccccacc ggaaagcact ttagctggct ttttgatgtc gtcctggctg aacagcaaac
    15901 gaccgagaat actgcgtacc gcctgctcgt catcgccttc ctgcttccac tggctcatcc
    15961 attcgaacac ggtcagatca ttttcaaact catattcgtg gtcctgagca tagtaaccaa
    16021 tgcgcgcgtt ctcagaccat tttacggtgc cgctgtccgg ttgcagatcg cccaccagcg
    16081 ttttcagcag cgttgattta ccgacgccgt tggtacccag taccgccagt ttttcaccca
    16141 cttccagcag caggttgaga tttttaaaca gcggaccgtt atcaaaccct ttggtcagac
    16201 cttccacttc cagcgcgtta cggaacagtt tcttatcctg ttcaaaacgg atgaacgggt
    16261 tctgacggct ggaggctttc acctcttcca gtttgatttt atcaatctgg cgcgcgcgcg
    16321 aagttgcctg gcgagatttc gaggcgttgg cgctaaagcg gctaacgaaa gattgcaact
    16381 cagcaatctg cgctttcttc ttggcgttat cggccagcag acgttcacgc gcctgggtcg
    16441 ccgccgtcat gtactcatcg tagttacccg gataaacgcg cagctcgccg taatccagat
    16501 ccgccatgtg ggtacagacc atgttaagga agtgacggtc gtgcgagatg atgatcatgg
    16561 tgctgtcacg ctcgttcagc acctgttcca gccagcgaat ggtgtcgatg tcgaggttgt
    16621 tggtcggttc gtcgagcagg agaatatccg gatcagcaaa cagcgcctgc gccagaagca
    16681 cacgcagctt ccagccagga gcaacttcac tcatcgggcc gtagtgctgt tccactggaa
    16741 ttcccacgcc aagcaacagt tcaccggcgc gagcttccgc agagtaaccg tccatttcgc
    16801 cgtatttaac ttccagatcg gccactttat agccgtcttc ttcactcatt tccggcaaag
    16861 catagatgcg gtcgcgctcc tgcttcactt cccacaactc tttatgcccc atgatcaccg
    16921 tatccagcac agtgaactct tcaaaggcaa actgatcctg acgcagttta ccaatgcgct
    16981 cgttgggatc gagggaaacg ttacccagcg tcggctcaag gtcgccgccg aggatcttca
    17041 taaaggtgga tttaccacta ccgttcgcgc caatcaggcc gtaacggttg ccgccgccaa
    17101 atttgacgga aatgttttca aacaacggct tactgccgaa ctgcatggtg acgttactgg
    17161 aaactaacac aggcgtatcc tgaaaagaga tatgacaaac cgcgcattat gccataagtc
    17221 tgaaagaaga tcctgctcct cgcttaaggt ctacactcaa gccaaaggca aaaaatgtga
    17281 tttcgtacac atctgatttc actgtgagct ggaatgaact tataatgcgc ttccaatact
    17341 ctaatattct caacccaatg gcctgccagg cacaaaatct cgcttaacat gaatatgaaa
    17401 ttgaaaacat tattcgcagc ggccttcgct gttgtcggct tttgcagtac cgcctctgcg
    17461 gtaacttatc ctctgccaac cgacgggagt cgcctggttg gtcagaatca ggtgatcacc
    17521 attcctgaag gtaacactca gccgctggag tattttgccg ccgagtacca gatggggctt
    17581 tccaatatga tggaagcgaa cccgggtgtg gataccttcc tgccgaaagg cggtactgta
    17641 ctgaacattc cgcagcagct gatcctgccg gataccgttc atgaaggcat cgtcattaac
    17701 agtgctgaga tgcgtcttta ttactatccg aaagggacca acaccgttat cgtgctgccg
    17761 atcggcattg gtcagttagg caaagatacg cctatcaact ggaccaccaa agttgagcgt
    17821 aaaaaagcag gcccgacctg gacgccgacc gccaaaatgc acgcagagta ccgcgctgcg
    17881 ggcgaaccgc ttccggctgt cgttccggca ggtccggata acccgatggg gctgtatgca
    17941 ctctatatcg gtcgcctgta tgctatccat ggcaccaacg ccaacttcgg tatcggcctg
    18001 cgtgtaagtc atggttgtgt gcgtctgcgt aacgaagaca tcaaattcct gttcgagaaa
    18061 gtaccggtcg gtacccgcgt acagtttatt gatgagccgg taaaagcgac caccgagcca
    18121 gacggcagcc gttatattga agtccataac ccgctgtcta ccaccgaagc ccagtttgaa
    18181 ggtcaggaaa ttgtgccaat taccctgacg aagagcgtgc agacagtgac cggtcagcca
    18241 gatgttgacc aagttgttct tgatgaagcg attaaaaacc gctccgggat gccggttcgt
    18301 ctgaattaat cttcaaaact taaagcaaaa ggcggactca taatccgcct tttttatttg
    18361 ccagacccta gttggccggg agtataacta acaaaacata tcccaccaac gccgcccaaa
    18421 acagcatcgg tattgaatag agatggaaac gccaccagat gcggcgatcg ttcgccatac
    18481 gtagcgcaat caaatttgcc agcgatccgg gtaataaccc aaagccacct acgtttaccg
    18541 cccataccag taataaagac ggcggcacat agttcagcaa caatatggta ctcggcacgt
    18601 tactgatcac ctgcgataaa ccgattgccg ttaaccataa cccgggttca gatagatgac
    18661 tcacgttacc caacacgcct tgcaacgctg gaagctgggt cagtaaatgg acgtcgataa
    18721 acatcgccat aaacaccagc agcagcgtcc agtccacact gagcaccacg cgacgtgcca
    18781 gcagcgcaaa gcctgccgcc acaatcacca gtccccacag ctcttgtttg aactccagcg
    18841 ccgtcagaaa gacgatatac agccccagac aactccacac cagccgcggt ttccactccg
    18901 gtgtttgcac ccccgtatgg tattgcatcg cctttccagg gaaacaacac cagcacagga
    18961 gcaggagcgt cagcatcatt gcgccagcca gcggtgccat ttgggcaata aatccggcaa
    19021 acgaaagacc agaacgtccc cagataagaa tattttgcgg gttgccaatt ggcgtcagta
    19081 gcgaaccagc gttgactgcc agcgcctcaa aaataatcag ccgattaacc gggatctcac
    19141 acagtctttt tagcgtgata gtcagcggaa caacaataaa cagcgcgaca tcgttggtca
    19201 gaaaggtaga aagcagcgcc gccgccagca ccataaacat cgccagccga cgctccgtag
    19261 caaagcggcg caccattttg cgccccagca catcaaaata accgcttaac tccacacctt
    19321 tggtcagcag catcaggccg cttaaggtga tgatggtgtg ccagtcgata gcagcaggcc
    19381 aggatttcgg tgcaaagggc acgaaaaagc ttaatccgat accaacaaga attaataact
    19441 gaaaaaaacg atcgccttgc agcgtgcgta aaaaaggcag gctcatttgg caccgtgttt
    19501 ctgggtaaac aaacgaaaag cgtcgagcgt ctcttcacta acatggtgct ccatgccttc
    19561 cgcgtcgcga cgggcgattt ccggactgac gcccaacacc aacaagaaat tttcgactat
    19621 ctgatgtcgc tcgcggcttt cctgcgccag cttctctcct tctgccgtta aaaacacgcc
    19681 acgccagggg atcatttcaa tcagccccat ggttgccagc cgcttaagca ttttagccac
    19741 cgtcggttgc gaaactccca gacgagcagc catgtccacc tgacgagctt cccccacttc
    19801 cctgatcaag tcagaaatca gctcaacgta atcatcaata agctcgcgcc gatgcgcctc
    19861 tctgacctgg cggaaccctt caacgtgctc ttccacgttc actaactgcg tcactttttt
    19921 tgctgttggc gtacctgcgc gacgactcat tgtgcttcct cattatggtg acgcatacat
    19981 agcgttctca tttcgtgcgc acattgtaaa ccagagttgc gaaggtacaa aaaattaacg
    20041 ttttagcaat agctatataa tatagcctgt gctatatctg tatgtaatgc aatcatccct
    20101 caaggatcga cgggattagc aagtcaggag gtcttatgaa tgagttcaag aggtgtatgc
    20161 gcgtgtttag tcattctccc tttaaagtac ggttaatgct gctctctatg ttgtgcgata
    20221 tggtcaacaa caaaccgcag caagataaac cttccgataa atagcggcgt cgcggtacgc
    20281 cgcttcactc ctgctttcat gcaggcataa cgcgttttgg tctgaaaaac cccacttttt
    20341 gtcggatttg caatcccctt cgcaaaagat ttgttcgtca gtagttgacc tgaacggcgg
    20401 ctcgctctat cttcttgcag ccctgcgtat attgcggctc gcggatgcgg acccctttcc
    20461 actcttcacg cactcttgca ggtattgacc cttgacgcca gggtaagcac atggcgtttg
    20521 ttacgatagt ggcatatgaa tttaaccctc aaagaatcgc ttgttacccg tagccgggta
    20581 tttagcccgt ggactgcgtt ctacttttta cagtcgctat taattaacct cggcttaggt
    20641 taccccttca gtttgctcta caccgctgcg tttacggcta ttttgctttt gctatggcga
    20701 acattgcctc gcgtacaaaa agttctggtc ggtgtcagtt cgctggtggc ggcttgttat
    20761 ttcccttttg ctcaggccta cggcgcgcct aatttcaata cattgctggc attgcactcc
    20821 accaatatgg aagagtcgac cgaaatcctg acgatttttc cgtggtacag ctacctggtc
    20881 ggcttattta tttttgcgct cggcgtaata gcaatcaggc gaaaaaaaga gaatgaaaaa
    20941 gcgcgctgga ataccttcga cagcctgtgt ctggtattca gtgtggcgac attttttgtt
    21001 gctcccgtgc aaaacctggc ctggggtggc gtatttaaac tgaaagatac tggctatccg
    21061 gtatttcgtt ttgctaagga tgtcatcgtc aataataacg aggtgattga agagcaagaa
    21121 cggatggcaa aactttccgg aatgaaagat acctggacgg tcactgccgt taagccgaag
    21181 tatcagacct atgtggtggt gatcggtgaa agcgcgcgtc gcgatgccct cggtgccttt
    21241 ggcggtcact gggacaatac cccgtttgcc agcagcgtta acggtttgat atttgctgac
    21301 tacattgccg ccagtggctc cacgcagaaa tcgcttggct taacgctcaa tcgcgttgtc
    21361 gatggcaaac cacagtttca ggataacttt gtcaccctgg caaatcgcgc gggcttccag
    21421 acctggtggt tttccaacca gggtcaaatc ggcgaatacg ataccgctat cgccagcatc
    21481 gccaaacgag cagatgaagt gtacttcctg aaagaaggta attttgaagc agataaaaac
    21541 accaaagacg aagcgttact ggatatgacc gctcaagtgc tggcgcaaga gcactcgcaa
    21601 ccgcagctga ttgttctaca tctgatgggc tcacatccgc aggcctgcga caggacacaa
    21661 ggaaaatacg aaacctttgt gcaatcgaaa gaaacgtcgt gctatctcta taccatgacg
    21721 caaacggacg atttactgcg caagctgtac gatcagttac gcaacagcgg cagcagcttc
    21781 tcgctggttt acttttctga ccacggtctg gcctttaaag agcgcggtaa agacgtgcaa
    21841 taccttgccc atgatgataa atatcagcaa aatttccagg tgccttttat ggtcatttcc
    21901 agcgacgata aagcgcatcg tgtgattaaa gcccgccgct cagccaatga cttcttaggc
    21961 tttttctccc agtggacggg gattaaagcg aaggaaatta acatcaaata cccgtttata
    22021 tctgagaaga aagccgggcc gatatacatc accaacttcc agttacagaa ggtggattac
    22081 aaccatctcg gaaccgatat tttcgacccg aaaccttaaa aacaaaaatc cgccccgaga
    22141 ggcggatttt ttatatcacc aaagtgatta gaagcggtaa ccaacaccgg caatccaggt
    22201 gcctacgtca acgctacgaa tacggctctg ctcgtaagag aagtccagag caacgttttc
    22261 catcgggttg aactgcagac ccgcaccgta ggagaaaccg tagtcgctgg tgtcgtgttt
    22321 gtaggtcggg tattcagtgg tctggaattt accataaccc acacccacta caccgtagat
    22381 gcttgcccag tcgttaatgc ggtaagccgg accagcagtg atgccgtagt actggttttt
    22441 gttgtagtca ccagagcttg cagtacggct tttctcggtg taagtgaaag aaccgatcac
    22501 acccagcggg ctgttgtctt cttcatagcg gtatttcagg ttgaaaccgc ccattttgtt
    22561 catttggccc tgagcgtcgc tctgtgcgta accgccagtt acagtagaag tcgcagctac
    22621 ggaagtacct gcggtgaaag ccagaactgc ggccagtgct gaaagacatg caattttttt
    22681 cataaccacc tcaaatgtga ttcaaataag tcctaagttt taaatatatc aaaaattaat
    22741 gggaaactct tcgcgatttg tgatgtctaa cgggccattt catgtaacag aacgtttcca
    22801 tacaccgcta tccatctaaa tttaaatcac tttttcagag aactgcgtaa gtattacgca
    22861 tgttttccct gtcattcatc cagattattc ctaatcacca gactaatgat tccatcaatc
    22921 ctggcgcatt ttagtcaaaa cgggggaaaa ttttttcaac aaatgctcaa ccagcattgg
    22981 gtatatccag tacactccac gctttactta agtctagata tttgtgggag aaaggatgcc
    23041 tggttcatta cgtaaaatgc cggtctggtt accaatagtc atattgctcg ttgccatggc
    23101 gtctattcag ggtggagcct cgttagctaa gtcacttttt cctctggtgg gcgcaccggg
    23161 tgtcactgcg ctgcgtctgg cattaggaac gctgatcctc accgcgttct ttaagccatg
    23221 gcgactgcgc tttgccaaag agcaacggtt accgctgttg ttttacggcg tttcgctggg
    23281 tgggatgaat tatctttttt atctttctat tcagacagta ccgctgggta ttgcggtggc
    23341 gctggagttc accggaccac tggcggtggc gctgttctct tctcgtcgcc cggtagattt
    23401 cgtctgggtt gtgctggcgg ttcttggtct gtggttcctg ctaccgctgg ggcaagacgt
    23461 ttcccatgtc gatttaaccg gctgtgcgct ggcactgggg gccggggctt gttgggctat
    23521 ttacatttta agtgggcaac gcgcaggagc ggaacatggc cctgcgacgg tggcaattgg
    23581 ttcgttgatt gcagcgttaa ttttcgtgcc aattggagcg cttcaggctg gtgaagcact
    23641 ctggcactgg tcggttattc cattgggtct ggctgtcgct attctctcga ccgctctgcc
    23701 ttattcgctg gaaatgattg ccctcacccg tttgccaaca cggacatttg gtacgctgat
    23761 gagcatggaa ccggcgctgg ctgccgtttc cgggatgatt ttcctcggag aaacactgac
    23821 acccatacag ctactggcgc tcggcgctat catcgccgct tcaatggggt ctacgctgac
    23881 agtacgcaaa gagagcaaaa taaaagaatt agacattaat taaatttaca tttctgca
//
LOCUS       DAPHKZ010000065        23852 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.065, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000065 DAPHKZ010000000
VERSION     DAPHKZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23852
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.065"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            21..539
                     /locus_tag="RH288_002717"
     CDS             21..539
                     /locus_tag="RH288_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HDV4031760.1"
                     /translation="MMKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQE
                     TKTVNIISILPAKVAVDNSQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVG
                     GGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNET
                     RIQPNTKCPEKS"
     gene            555..1094
                     /locus_tag="RH288_002718"
     CDS             555..1094
                     /locus_tag="RH288_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HDV4031761.1"
                     /translation="MKKVFLCAILASLSYPAIASSLQDQLSAVAEAEQQGKNEEQRQH
                     DEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEASADKKRDQSYE
                     DELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
                     DLMKSVGKAEENKSDSWFN"
     gene            complement(1187..2764)
                     /gene="guaA"
                     /locus_tag="RH288_002719"
     CDS             complement(1187..2764)
                     /gene="guaA"
                     /locus_tag="RH288_002719"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDV4031762.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEA
                     SNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(2833..4299)
                     /gene="guaB"
                     /locus_tag="RH288_002720"
     CDS             complement(2833..4299)
                     /gene="guaB"
                     /locus_tag="RH288_002720"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDV4031763.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            4461..5831
                     /gene="xseA"
                     /locus_tag="RH288_002721"
     CDS             4461..5831
                     /gene="xseA"
                     /locus_tag="RH288_002721"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDV4031764.1"
                     /translation="MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESM
                     QPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVL
                     KRRDPSLPVIIYPAAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFTSRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQS
                     TRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQL
                     KRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTH
                     LEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKK
                     SRKKVH"
     gene            complement(5828..6043)
                     /locus_tag="RH288_002722"
     CDS             complement(5828..6043)
                     /locus_tag="RH288_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417005.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDV4031765.1"
                     /translation="MELHCPQCQHVLDQDNGHARCRSCGEFIEMKALCPDCHQPLQVL
                     KACGAVDYFCQHGHGLISKKRVEFVLA"
     gene            complement(6113..7585)
                     /gene="der"
                     /locus_tag="RH288_002723"
     CDS             complement(6113..7585)
                     /gene="der"
                     /locus_tag="RH288_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDV4031766.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMG
                     SPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK"
     gene            complement(7703..8881)
                     /gene="bamB"
                     /locus_tag="RH288_002724"
     CDS             complement(7703..8881)
                     /gene="bamB"
                     /locus_tag="RH288_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HDV4031767.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTP
                     TTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDG
                     WFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
                     LVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSA
                     VLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYN
                     GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
                     "
     gene            complement(8892..9512)
                     /gene="yfgM"
                     /locus_tag="RH288_002725"
     CDS             complement(8892..9512)
                     /gene="yfgM"
                     /locus_tag="RH288_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ancillary SecYEG translocon subunit YfgM"
                     /protein_id="HDV4031768.1"
                     /translation="MEIYENENDQVEAVKRFFAENGKALAVGVILGVGALIGWRYWNS
                     HQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAAENKNTYGALASLELAQQFVDKN
                     ELEKAAAQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDTIKGEGWAAIV
                     ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI"
     gene            complement(9530..10804)
                     /gene="hisS"
                     /locus_tag="RH288_002726"
     CDS             complement(9530..10804)
                     /gene="hisS"
                     /locus_tag="RH288_002726"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDV4031769.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQAL
                     LNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLV
                     ASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEV
                     ANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            complement(10915..12033)
                     /gene="ispG"
                     /locus_tag="RH288_002727"
                     /gene_synonym="gcpE"
     CDS             complement(10915..12033)
                     /gene="ispG"
                     /locus_tag="RH288_002727"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDV4031770.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK"
     gene            complement(12060..13073)
                     /gene="rodZ"
                     /locus_tag="RH288_002728"
     CDS             complement(12060..13073)
                     /gene="rodZ"
                     /locus_tag="RH288_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HDV4031771.1"
                     /translation="MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQ
                     GQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANV
                     DTAATPAPTAATTPDGAAPLPTDQAGVTTPVADPNALVMNFTADCWLEVTDATGKKLF
                     SGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQS
                     PAQ"
     gene            complement(13358..14512)
                     /gene="trmG/rlmN"
                     /locus_tag="RH288_002729"
     CDS             complement(13358..14512)
                     /gene="trmG/rlmN"
                     /locus_tag="RH288_002729"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HDV4031772.1"
                     /translation="MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQ
                     VMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQ
                     RVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
                     AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPA
                     LDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVT
                     IEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVL
                     MSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV"
     gene            complement(14662..15093)
                     /gene="ndk"
                     /locus_tag="RH288_002730"
     CDS             complement(14662..15093)
                     /gene="ndk"
                     /locus_tag="RH288_002730"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDV4031773.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR"
     gene            complement(15242..17554)
                     /gene="pbpC"
                     /locus_tag="RH288_002731"
     CDS             complement(15242..17554)
                     /gene="pbpC"
                     /locus_tag="RH288_002731"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417014.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HDV4031774.1"
                     /translation="MPRLLTKRGCWITLAAAPFLLFLAAWGADKLWPLPLHEVNPARV
                     VVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARA
                     AWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
                     LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEAA
                     RNKVLERMAVQGVWSREQVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKITTTL
                     DAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFGHVDMV
                     NSIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLEDMAA
                     AYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAQPLPDSALPRVAPL
                     AWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLS
                     RSANLPEDPRPNSVTRGVICWPGGQSLPEGDGNCRRRLATWLLDGSQPPTLLLPEQEG
                     INGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTSCP
                     PYGHDAQLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRN
                     VTLHLTDKGDYQLLVMDDVGQIATVKFVMQ"
     gene            complement(17555..22516)
                     /gene="yfhM"
                     /locus_tag="RH288_002732"
     CDS             complement(17555..22516)
                     /gene="yfhM"
                     /locus_tag="RH288_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha2-macroglobulin"
                     /protein_id="HDV4031775.1"
                     /translation="MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSEN
                     ASSAKLSVPERQKLAQQSAGKVLTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIH
                     VVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTIT
                     TRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRN
                     SLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAG
                     RYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQA
                     TSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFG
                     PRDLYRPGETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQPENGLYHFTW
                     PLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSV
                     VGYYLYGAPANGNTLQGQLFLRPLREAVSALPCFEFGDIAAENLSRTLDEVQLTLDDK
                     GRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASK
                     SVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSE
                     DEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAG
                     YSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWW
                     QEIDVRAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDEN
                     RRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDP
                     WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVVQQA
                     LPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRF
                     MASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVRTTLFIPVR
                     ALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAI
                     PADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAA
                     QLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLV
                     RAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQ
                     KAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIALALKTPRNSDERIW
                     LGDYGSSLRDNALMLSLLEENKLLPDEQYTLLNTLSQQAFGERWLSTQESNALFLAAR
                     TIQDLPGKWQAQTSFSAEQLTGEKAQNSNLNSDQLVTLQVSNSGDQPLWLRMDASGYP
                     QSAPLPANNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLP
                     AGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPV
                     TLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP"
     gene            22723..23568
                     /gene="sseA"
                     /locus_tag="RH288_002733"
     CDS             22723..23568
                     /gene="sseA"
                     /locus_tag="RH288_002733"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HDV4031776.1"
                     /translation="MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLN
                     GHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAP
                     RAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDV
                     LLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDE
                     LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP
                     VEPVK"
BASE COUNT         5705 a         6611 c         5936 g         5600 t
ORIGIN      
        1 aatgtgtata acaaggaata gtgatgaaat ttaaaaaatg tcttctgcct gtggcaatgt
       61 tagcgtcatt cactctggca ggatgccagt caaatgctga cgatcatgct gccgatgttt
      121 atcaaaccga tcaactgaat accaaacaag aaactaaaac cgttaatatt atttccattc
      181 ttcccgcaaa agttgccgta gacaactccc aaaataaacg gaacgcacaa gccttcggcg
      241 cgcttattgg cgcagtcgct ggcggtgtta tcggccacaa cgtcgggtct ggcagcaatt
      301 ccggaacgac ggcaggtgca gttggcggcg gagctgtagg cgcggcagcg ggttctatgg
      361 tgaatgataa aaccttagtg gaaggtgttt ctttaaccta taaggaaggc accaaagtgt
      421 atacctctac ccaggtgggt aaagagtgcc agtttacgac aggtttagcc gttgttatta
      481 ccacgacgta taacgaaacg cgtattcagc caaataccaa atgtcctgaa aagagctaat
      541 aatcaggagg agtcatgaag aaagtttttc tttgcgccat cttagcctcc ttaagctatc
      601 cggctatcgc ctcatcattg caggatcaac tctctgctgt cgcagaagcg gaacagcaag
      661 gtaaaaatga agagcaaagg cagcatgacg aatgggtcgc ggagcgcaac agggaaatcc
      721 agcaagagaa gcaacgtcgc gcaaatgccc aggccgccgc taacaaaaga gcggcaacgg
      781 cagcggcaaa taagaaagct cgtcaggata aactggacgc cgaagcctct gcggacaaaa
      841 aacgcgatca aagttatgaa gatgagctac gcagcttaga gattcagaaa caaaaactgg
      901 cgctggcgaa agaagaagcc cgcgttaagc gagaaaacga atttatcgat caggaactga
      961 agcacaaagc tgcgcaaacc gatgtggtgc aatctgaagc tgacgccaac agaaatatga
     1021 ctgaaggcgg tcgcgatctg atgaaaagcg tgggcaaagc agaagagaac aaatcggaca
     1081 gctggtttaa ttaatcgatg ttagtaactt caatcctata attcttgaag ataaaaaacc
     1141 ctctgtagta acagagggtt ttgttcattc atagtgcagg gtcaaatcat tcccactcaa
     1201 tggtagctgg cggcttgccg ctgatgtcat acaccacgcg ggaaataccg ttcacttcat
     1261 tgataatgcg gttggaaacg cgaccgagga aatcgtacgg cagatgcgcc cagtgtgcgg
     1321 tcataaagtc gatggtttcg acagcacgca gagagacaac ccagtcatac ttacgaccat
     1381 cgcccattac gccaacggaa cgtaccggca ggaacacagt gaacgcctgg ctgactttgt
     1441 cgtacaggtc cgctttacgc agttcttcaa tgaagatggc gtcagcacgg cgcagcaggt
     1501 cacagtactc tttcttcact tcacccagaa cacgaacgcc aaggcctggt cccgggaacg
     1561 ggtgacggta cagcatgtcg tacggcaggc ccagctccag accaatctta cgcacttcgt
     1621 ctttgaacag ctctttcagc ggttcaacca ggcccatctt catctctttc ggcaggccgc
     1681 ccacgttgtg gtgagatttg atgacgtgtg ctttaccggt tgcagacgcc gcagattcga
     1741 taacgtcagg gtagatggtg ccctgcgcca gccacttcac gtcttccagt ttcagcgctt
     1801 cttcatcgaa tacttcaacg aaaacgcgac cgatgatttt acgttttgct tccggatcgt
     1861 tttcgccagc cagcgctgac aggaagcgat cttctgccgg tacgtgaaca atgttaagac
     1921 caaagtgatc gccaaacata tccagaacct gctctgcttc gttgaggcgc agcaggccgt
     1981 tgtcgacgaa tacgcaagtc aggtttttac cgatagcgcg gtgcagcagc attgcggtta
     2041 cggaggaatc cacaccacca gagaggccga ggatgacttt atcgtcgcct acctgctcgc
     2101 ggatgcgagc tacagcatcg tcgataattt tcgctggcgt ccacagggct tcacactggc
     2161 agatatcacg cacaaaacgc tccagcatgc gcataccctg gcgggtgtga gtcacttccg
     2221 ggtggaactg tacgccatag aagcgttttt cttcgttagc cataatggca aacgggcagc
     2281 tttcggtgct ggctacggtg atgaagtcgg acggaatagc ggtaacttta tcgccgtggc
     2341 tcatccagac atcgagcagc ggtttaccgt ctgcggtcag cgcatcttcg ataccgcgaa
     2401 ccagtgcgct gtcgtttacg acttcaacct gcgcgtagcc aaattcacgt tcgttagagg
     2461 cttcaacgtg accgcccaac tgcattgcca tggtctgcat gccatagcaa acgccgaata
     2521 ccggtacgcc tgcttcaaag acatactgcg gcgcacgcgg actgttttct tcagtagtac
     2581 tttccgggcc gccggaaaga ataatgccgc ttggattgaa gtcacgaatt tgtgcttctg
     2641 tcacatccca cgcccacagt tcgcagtaaa cacccagctc acgcacgcgg cgcgcaacca
     2701 gttgagtgta ctgagaaccg aagtccagaa tgaggatgcg atgcttatga atgttttccg
     2761 tcattgacgc ttattccgag gcaagtgaaa cagataatat aaatcgcccg acatgaagtc
     2821 gggcgaagag aatcaggagc ccagacggta gttcggggac tctttagtaa tggtcacgtc
     2881 gtgaacgtgg ctttcctgaa tgcccgcacc gctgatacgt acaaactccg ctttagtacg
     2941 cagttcgtcg atagtaccac agccggtcag acccatacag gagcgcaggc cgcccatctg
     3001 ctggtgaatg atctctttca ggcgaccttt ataggctacg cgaccttcga taccttccgg
     3061 caccagtttg tcggcagcgt tatcgctctg gaaataacgg tcagaggaac ctttggacat
     3121 cgcgcccagg gaacccatac cacggtaaga tttgtaagaa cggccctggt agagttcgat
     3181 ttcacccgga gattcttcag tacccgccag catggaacct accatcaccg cgcttgcgcc
     3241 agcggcgata gctttggcga tgtcgccgga gaagcgaata ccgccatcag cgataaccgg
     3301 aataccggtg ccttccaggg cttctactgc gtcagcaaca gcggtaatct gcggaacacc
     3361 gacgccagtc acgatacgag ttgtacagat agagccaggg ccaatgccga ctttaaccgc
     3421 actgcaacca gcttctgcca gagcgcgtgc acctgcagct gttgccacgt tgccgccgat
     3481 aatttgcaga tccggatatt tagcacgggt ttcacggata cgttgcagta caccttctga
     3541 gtgaccgtgg gaggagtcga tcagcagaac gtcaacgcct gcggcaacca gcgcgtcaac
     3601 acgctcttcg ttacccgcac ctgcgccaac cgctgcacca acacgcagac ggccttgctc
     3661 gtctttacag gcgttcggtt tacgttccgc tttctggaag tctttcacgg tgatcatgcc
     3721 gatcaggtgg aattcgtcat caaccaccag cgctttttca acgcgttttt cgtgcatttt
     3781 tgccagcacc acttcacggg cttcaccttc acgcacggtg accagacgct ctttcggcgt
     3841 catgtaaacg ctaaccggct ggttcaggtc ggtaacaaaa cgcacgtcac gaccggtgat
     3901 aatacccacc agttcgtttt cttcggtaac gaccggatag cccgcaaaac cgttacgctc
     3961 ggtcagttct ttcacttcgc gcagcgtcgt ggttggcaga acagtctgcg gatcagtcac
     4021 cacaccagat tcgtgttttt tcacacggcg aacttcttct gcctggcgtt caatggacat
     4081 gtttttgtgg ataaagccga taccgccttc ctgagccaga gcaatagcca ggcgcgcttc
     4141 cgttacggta tccattgctg cggaaagcat agggatattc agacgaatag ttttcgtcag
     4201 ctgggtgctg aggtcagcag tattcggcag aacggtagag tgagcaggaa cgaggagaac
     4261 gtcgtcaaac gtcagagctt ctttagcgat acgtagcatg ggcaatatct cgaccagagt
     4321 ggttaataaa tattgccgcg gcattataca gagcgtaacc gattgcatct accccttttt
     4381 gcaaaaaatg cttgctatcc ccgaagggcg ggttactatc gactgaataa cctgctgatt
     4441 tagaatttga tctcgctcac atgttacctt ctcaatcccc tgcaattttt accgttagtc
     4501 gcctgaatca aacggttcgt ctgctgcttg agcatgagat gggacaggtt tggatcagcg
     4561 gcgaaatttc taatttcacg caaccagctt ccggtcactg gtactttaca ctcaaagacg
     4621 acaccgccca ggtacgctgc gcgatgttcc gcaacagcaa ccgccgggtg accttccgcc
     4681 cacagcatgg gcaacaagtt ttagttcgcg ccaatattac gctctacgag ccgcgcggcg
     4741 actaccagat aatcgttgag agtatgcagc cggccggtga agggctgctg caacagaagt
     4801 acgaacagct caaagcgaag ttgcaggctg aaggtttgtt cgatcagcaa tacaaaaaac
     4861 cacttccctc ccctgcgcat tgcgttggtg tgatcacctc aaaaaccggt gctgcgctac
     4921 atgatatttt gcatgtgtta aaacgtcgcg atccttctct gccggtgatc atctaccctg
     4981 ccgccgttca gggcgatgac gcgccggggc aaattgttcg cgccattgaa ctggcgaatc
     5041 agcgcaatga gtgcgacgta ttgatcgtcg ggcgcggcgg cggttcgctg gaagatttat
     5101 ggagttttaa cgacgaacgc gtagcgcggg cgatttttac cagccgcatt ccggttgtca
     5161 gcgccgtcgg gcatgagacg gatgtgacca ttgccgattt tgttgccgat ctgcgtgcgc
     5221 caacgccgtc tgccgccgct gaagtagtga gccgtaatca gcaagagtta ctgcgccagg
     5281 tgcaatcgac ccgtcaacgg ctggagatgg cgatggatta ttatctcgcc aaccgcacac
     5341 gtcgctttac gcaaattcat caccgattac agcaacagca tccgcagctc cggctggcac
     5401 gccagcaaac catgcttgag cgcctgcaaa agcgaatgag ctttgcgctg gaaaatcaac
     5461 ttaagcgtac cgggcaacag cagcagcggt taacacagcg gctgaatcag caaaatccac
     5521 agccgaagat tcatcgcgcg caaacgcgca ttcagcaact ggaatatcgt ttagcagaaa
     5581 ccctgcgcgc acagcttagc gccacgcgtg aacgtttcgg taatgcagta acgcacctcg
     5641 aagccgtaag cccactgtca acgctggcgc gtggatacag cgttactact gctactgacg
     5701 gcaatgtact gaaaaaagtg aagcaagtta aagcgggtga aatgctaacc acacgtctgg
     5761 aagacggctg gatagaaagt gaagtaaaaa acatccagcc agtaaaaaaa tcgcgtaaaa
     5821 aggtgcatta agccagcacg aattcaacgc gttttttcga tatcaagcca tgcccgtgct
     5881 gacagaagta atctactgca ccacaggctt ttaacacctg caacggttga tggcagtctg
     5941 gacaaagagc tttcatttca ataaattccc cgcaggatcg gcaacgcgca tggccgttat
     6001 cctgatcaag cacatgctga cattgtggac aatgcagttc catatgaatt cctccggtag
     6061 ccattccctc tacattcata gagggaatgg cagataaaat acttacggat aattatttat
     6121 ttttcttgat gtgcttcatc agacgcttac gtttacgcat ctgggttggc gtcagggtgt
     6181 tacgcttatt cgcatacggg ttttcccctt ctttgaactg aatacgaatc ggcgatccca
     6241 ttacgtccag cgatttgcgg aagtagttca tcaagtagcg cttgtaggaa tcaggcaggt
     6301 ctttcacctg attaccgtga atcaccacaa tcggcgggtt ataaccaccg gcgtgggcat
     6361 atttcagctt cacacgacga ccgcgtacca gcggcggttg gtgatcttca acagccatcg
     6421 tcatgatgcg cgtcagcata gaggtcccca cacgacgggt ggagctgtca tacgcttcac
     6481 gtactgattc aaacaagtta ccaacaccac tgccgtgcaa ggcagagata aagtgcacac
     6541 gagcaaaatc gataaagccc agacggaagt ccagcgtttc tttcacctgc tctttcactt
     6601 cctgactcag gccatcccac ttattcacca caatgacaag tgagcgccca ctattgagaa
     6661 taaagcccag cagcgagaga tcctgatcgg aaataccttc gcgcgcatca atcactaaca
     6721 tcaccacgtt ggcgtcttca atggcctgca acgttttgat tacggagaat ttctctacag
     6781 catcggtgat tttgccgcgt ttacgtacgc cagcggtgtc aatgagcaca tactcacgtc
     6841 catcgcgttc cattgggatg tagatgctgt cacgcgtcgt gccaggcatg tcgtaaacaa
     6901 caacgcgctc ttcaccaaga atacggttag tgagtgtaga cttacctacg ttcggacgac
     6961 ccacaatcgc cagtttgatc ggcagacttt gcgggtcgaa gtcgtcttcc tcttcttctt
     7021 cgccgttctc ttccgcttca aattgcgccc agtattcagc gtcttcgtcg acttcctctt
     7081 gcggtgcgag atcttccatc cacggcagca gcacatgctc cagcagactt aatacgccac
     7141 gaccgtgaga cgcggcgatc gggtagattt cacctaaacc aagcgagtag aaatcaacca
     7201 ctgcctgatc gggatccaga ccgtcagttt tgtttgccac caggaaggtc ggtttttcac
     7261 gggagcgcag atgtttggca atcgcttcat ctgccggcat caggcccgcg cgcgcatcca
     7321 ccataaacag tacgacgtcc gcttcttcaa tcgccagcag cgactgttcc gccatgcggg
     7381 tttctacacc gtcttctgtg ccatcaatcc cgccggtatc aatacagata aactcacggc
     7441 cttcaatttc cgcacgaccg tacttacggt cacgagtcag acccgggaaa tccgcaacca
     7501 gcgcatctcg ggtgcgagtt agacggttaa ataacgtgga ttttcctacg ttagggcgcc
     7561 cgacaagcgc gaccacaggt accatgttta aagcctcatt tttataaatc atcagacaac
     7621 gcacgctata ttcgcgtcgt tgttaaaaac aggaaaacgg cccctgtcca ggagccgttt
     7681 tcaaagtgaa cgacagagac gattaacgtg taatagagta cacggttccg tcttttgcct
     7741 ggatcagcag tttgccgtca gcggcaaccg gttcagtctg gaaaccggaa ctatcaactt
     7801 tttgctgggc aacgaaacga ccatcttcga cgttaatcca gtgcagataa ccttcactgt
     7861 caccgaccac caggttgcca ttatacagca ccggagaagt cagcaggcga tgcagcagat
     7921 cgctttgtgt ccacagcgta acgccgccat caatggtcaa cgccatcacc cggtcatttt
     7981 gatcgaccag atagatgcga ttgccgtcga cgatgaaatc attcaccgaa cccagttcgc
     8041 gtttccacat aatctgacca ctgcgcagat caagcgccgt caggttacca ttataggcca
     8101 gcgcgaaaac aacgccgtta acaacgacgg gagtcgtgtc aacatcgctc agacggtcaa
     8161 tttcggtaga accggtcgcc tgggaaatac gctgctgcca aatcatctgg ccctgttcca
     8221 tcagcactgc gctgacgcga ccattatcgc cccccacgac ggccgcacca aaagccgttg
     8281 ccggcgcaga ctcgccacgc aaagagagcg aaggcatatc gaggttaact gtccatttga
     8341 cagcgccgtc agcttcgttc agcgcttgta actgaccgtt actggtgtgg attaacacca
     8401 gaccgtcgct gaccaccggg cgcgaaagtg cttcacccgc gactttagtt tgccatgcca
     8461 cagtaccatc gctggtattc agcgcgtaaa cctgcgcctt ttcgctgcca atgtagacat
     8521 gcccaccaga cacggtcaca ccgccagaaa gtaatgcagg ctctttagag aaccagccat
     8581 ctttctcggc caggctgaca gaccagattt ctttgccatc atccgcattc agcgctttta
     8641 ctaaaccagc gcggtccgct gcatagacaa cgttgtccgc cagtgccgga tgaagattgg
     8701 aatagaagtt gccaatgccg ctaccaacgg aagtgctcca cgccgtggtc ggcgtaaact
     8761 ggttttcaac ggttggcaat ggggacatct ttaccacatc ttcttcgctg ttaaacagcg
     8821 aacagccgct taaaagggta acggaaagca gtcctggcag cagtaattta cgcaattgca
     8881 tcgggtccct ctcagatgga caaattatta attttcatct gcatcatttc gctcagtgcc
     8941 ggagtaacat cgcttttcac gcctgcttcc catgcactac gcgcaccttg cttatcacct
     9001 ttgctcagca atgcttcacc acgcaggtcg gcaacaatgg cagcccaccc ttcacctttg
     9061 atggtatcaa gggttttcag cgcggcatca gcctgcttga gctgtacctg aacgcgagca
     9121 agacgcagat ttatcacggc tttgagattt tcatcgctcg tgtctgccag cccctgttgt
     9181 aactgggcgg cagctttctc tagttcattt ttgtcaacaa attgctgcgc aagttccaaa
     9241 gaagccagcg caccataagt atttttattt tcagcagcaa atttttccgc cgccgggatg
     9301 ctatccggtt tgccttcgct cactgcggta accgcatttt gataggcaag agaagcggag
     9361 cgtgcagaat caacctgatg gctgttccag tagcgccagc caatcagtgc gccaacgccc
     9421 aaaatcaccc caacagccag tgctttgcca ttttcagcaa aaaagcgttt aaccgcttct
     9481 acctggtcgt tttcgttctc gtaaatttcc acgctgtcct tctccttcct taacccagta
     9541 acgtgcgcaa atgcgcggct acgctatcct gcgcaactgc cgtttgctca ccagagcgca
     9601 aatccttcac tactgctgtg ccgttagcca cttcagactc acccagcacc acagcaacgc
     9661 gggcacccca tttatcagca cgggcaaact gtttcttaaa gttgccgccg ccgtggttgg
     9721 tcatcaattt cacgcccggt aattcatcac gcagacgctc agctaatgcc atagccgcag
     9781 attgtgtatc agcacctgaa gccaccaggt atatatcgac aacaggatcg gctttaaatt
     9841 ccggattaac ggcctgtact aacaatacaa gacgttcgag gcccatcgca aaaccgacag
     9901 ccggtgttgc acgaccgccc agttgttcca caagaccgtc ataacgaccg cctgcacaca
     9961 cggtgccctg ggagccgaga ctgttagtca cccactcgaa aacggtacgg ttgtagtaat
    10021 ccagaccacg caccagacgc tggtttacgg tgtaagcgat ccccgcgctc tccagcagtt
    10081 tgcacagacc ggcaaaatgc tcacgagatt cctcgtccag atagtcacct aatgccggag
    10141 cgtcgttgag aagcgcctgc acttccggat tttttgaatc cagcacgcgc agcgggttag
    10201 tgtacatgcg gcgtttgcag tcttcgtcca gcttttcttt atgctgctca aggaatgcca
    10261 ccagcgcatc gcggtaattg gcgcgtgctt ccagcgaacc gatagagttc agctcaagag
    10321 ttacgtgctc ggaaataccc agcgcgcgcc accagcgggc agtgagcata atcagttcag
    10381 cgtcgatatc cggaccttgc agaccgaaaa cttcgcagcc caactgatgg aactgacgat
    10441 aacgcccttt ctgcggacgc tcgtgacgga acatcggccc gatataccac agacgctgtt
    10501 cctgattgta cagaagacca tgctcgatgc cggcgcgtac acagcccgcc gtcccttcag
    10561 ggcgcagagt caggctgtcg ccattgcgat cctcaaaggt gtacatctct ttttcaacca
    10621 cgtcggtgac ttcaccaatc gcacgtttga atagcggggt ctgctctaca atcggcaagc
    10681 ggatttcact gtaaccgtag ctgccgagca cgtttttcag tgtgccttca atgcgctgcc
    10741 agatggccgt ttcgccaggc aggtaatcgt tcatgccgcg aatggcttga atgttttttg
    10801 ccacgtttat tctctttctg aatataaaaa tgaaccctca acgcttccct caatgtttcg
    10861 ggagccatgc gggttcaatc atacacggga agcgaggcgc ttcccatcac gttattattt
    10921 ttcaacctgc tgaacgtcaa ttcgacgcgc ttcgtccagc tgactggctt tcgcacgaat
    10981 gcgtgcttcc agctggtcga tcatatcgtt gttgtccaga cggtctttgc gcacgccatc
    11041 ttcatagagg ccgcttttct tgttgccgcc ggtgacgccg agtgtagaaa ccagcgcctc
    11101 acctgggcca ttcaccacgc agccgataat cgaaacgtcc atcggagtga tgatatcttc
    11161 caggcgttgc tccagcgcgt taaccgtacc gataacatca aattcctgac gcgaacaggt
    11221 cgggcaggcg atgaagttga tccctcgcga acggatacgc agcgatttca aaatatcgaa
    11281 accgactttg atctcttcga ccggatcggc cgccagcgat acgcgcagcg tgtcgccgat
    11341 gccttcagac agcagcagac ctaaaccaat ggcggatttt actgccccgc tgcgcgcacc
    11401 accagcttcg gtgatcccca gatgcaacgg ctgatcgatc tgttttgcca gcaaacgata
    11461 agactcaaca gcgaggaaga cgtcagacgc tttcacgctg actttgaact gatcgaagtt
    11521 caggcgatcg agatgatcaa catgacgcat ggcagattcc agcaacgcct gcggcgtcgg
    11581 ttcgccatac ttttcttgca gatctttttc cagcgatccg gcgttaacgc caatacggat
    11641 cggaatgttt ttatcgcgcg cacagtcaac caccatgcga atacgctctt cattaccgat
    11701 attgccaggg ttaatacgca gacaatcgac gccgtattcc gctactttca gcgcaatgcg
    11761 atagtcgaag tggatgtcag ccaccagcgg cacgttaacc tgctgtttga tgagtttgaa
    11821 cgcttctgcc gcgtccatcg tcggtacgga tacacggacg atatcagcgc caacgcgttc
    11881 cagcgccttg atttgattga ccgttgcttc gacgtctgtc gtacgcgtat tggtcatgga
    11941 ctgtacggcg atgggagcac catcgccaat cggcacattc ccaacgtaaa tacgtgttga
    12001 ttttctacgt tgaattggag cctggttatg catgaaaaat ctcccgcgtt acccgtctgt
    12061 tactgcgccg gtgattgttc ggcattgagg gtcagacgcg caacctggtt agttctgata
    12121 aaacgactca gatcgacagg tttcccttga tactggatct gtactgcggc tggcgcacca
    12181 attttcagtt tgtacggtgc ctggccggtt aagttcaaat taccgtcttt acgctgcata
    12241 ccgctaaaca attttttacc ggtagcatca gtgacctcca gccagcaatc ggcagtaaag
    12301 ttcatcacca gcgcattcgg atcagccacc ggcgtggtca cgccagcctg atcggttggc
    12361 aacggcgcag caccatctgg cgttgttgct gccgttggtg ccggggtcgc ggcggtatca
    12421 acatttgcct gcgaaggcga aacaaccgca ttctgttgcg gatcaacagc tggtgctggc
    12481 gcagttacgg caggtgtttg cgtgttggtt gcggtagtat ccacagacgc tggcggcgtg
    12541 gacgttgtag ccgggtctgt agttgtcgac gtatttaatg gaacactctg cccctgctcg
    12601 ctattactgc tcagttccgc cgaagattga tcggccatag tggtgatctc ttcctgctga
    12661 gctttgtggt cttgccacca ccaggcaccg ctcaggccga taaccacaaa caacaccagc
    12721 caagtgaagg tcatcagcca gccgtcgcgt tttttgcggc gtttaccgag ggaaaaactc
    12781 tgcatcggcg caacttttgc agcccgaagt ggagcctgct tttccagccc tggcagcagt
    12841 tcttcttctg gaatatgtac cagacgcgca taagagcgga tatatccgcg caggaatgtt
    12901 gaagcaagat cggcgggtgc cttatcttct tcaatgtcgc gtaccgtgga aaccttcagg
    12961 caaagtcgct cggcaacggc ctgctgacta agtcctagtt gttcgcgagc attacgcagg
    13021 cgagcgccgg tagtaagtgc ttcattttgg tcgtgcgtgg cttcagtatt cattcgctgc
    13081 aggtacgttt aaatgagaat tgagatgccg gtgaaccatc atgctcaccc acaccgcgaa
    13141 acatccgtta agttaaccgt tatcatacag tataagaccg tctgtgtgct cgtgacaaag
    13201 cccacattca ctaaggctaa cttactgttg catcgttaca tactgcctta aagtcagcaa
    13261 aaacgcaccg ttaatattga ccagacaatt gcaacttaat acttcattca taaaacatta
    13321 cgccacggta cataaagtaa ccgtggcgta atggctatca gaccgcttta atgtcgatgg
    13381 cttcaccctg catccgttta cgcagggtac gtttcgtacg gtcgataaca tcgcccgcca
    13441 actgaccaca ggcagcatcg atatcatcac cacgagtttt acgcacaata gtggtgaaac
    13501 cgtagctcat cagcactttt gagaaacggt cgatacggct gttcgagctg cgtccatacg
    13561 gcgcacccgg gaacgggttc cacgggatca ggttgatctt acacggcgta tctttcagca
    13621 gttccgccag ttggtgcgcg tgttcagtgc cgtcgttaac gtggtcaagc atcacgtatt
    13681 caatagtgac tcggccctga ttggcgttgg atttctccag ataacggcgc accgcagcaa
    13741 ggaacgtttc gatattgtac tttttgttga tcggcacaat ttcgtcacga atttcgtcgt
    13801 tcggcgcgtg cagggaaatt gccagtgcaa cgtcgatcat atcgcccagt ttatccagcg
    13861 ccggaactac accggaagtg gaaagcgtga cgcgacgttt agacaggcca aaaccgaaat
    13921 catcaagcat gatttccatc gccggaacga cgttgttcag gttgagcagc ggctcgccca
    13981 tgcccatcat cactacgtta gtgatcggac gctgaccggt gacttttgct gcgccgacga
    14041 ttttcgccgc acgccacacc tggccgataa tttccgacac ccgcaggttg cggttaaagc
    14101 cctgctgggc ggtggaacag aatttacact ccagcgcaca ccccacctgc gaagagacgc
    14161 agagcgtggc acggtcgtct tccgggatat acaccgtttc gacgcgctga tcgccaacgg
    14221 cgatcgccca tttaatggtg ccgtcagatg aacgctgttc ttcaaccact tccggtgcgc
    14281 ggatttccgc cacctctttc agtttgccgc gcaacacttt gttgatgtcg gtcatctcat
    14341 caaagttgtc gcagcaatag tgatacatcc acttcatcac ctgatcggcg cggaagggtt
    14401 tttcacctaa atctttaaaa aactcccgca tctgctgacg gttgagatcc agcaggttga
    14461 tttttccatc tttcgtggtg acgttttcag gtgtgactaa ttgttcagac atatgctatt
    14521 ccggcctcgt tattacacgt tatggcccct ggagggttga aaaaagaaac gccccggtga
    14581 gcggctgctc gtccgggggc gctgcattgt acaaattctg gcgcacggat gccacgtttg
    14641 cacgcggcat ttacgaaatt attaacgggt gcgcgggcac acttcgcctt cgccaaagaa
    14701 ataagcgatt tcgcgagcgg cagattcgac ggaatcagaa ccgtgggtac cgttttcggt
    14761 caggctgtca gcgtaatcag cgcgcagagt accagccagt gcgtttgccg gattggtcgc
    14821 gcccagcaga tcgcggtgac gctgaacggc gttttcacct tccagcacgg aaaccacgat
    14881 cgggccagag gtcatgaatt caaccagacc atcaaagaac ggttttccat cgtgttcagc
    14941 ataaaagcca cgtgcctgtt caacggtcag gtgcagcatt ttggtgccaa caattttgaa
    15001 ccctgcagct tcaaagcgcg caaagatatt accaatgacg ttttttgcta ccgcgttcgg
    15061 tttgatgatg gaaaaagtac gttcaatagc catttttacc tctgtaaatt gttctgttgt
    15121 tgtctgtacc agcgtacgag atggcgcgga ttataatgag caacagggcc gttgactatt
    15181 gatgaaggta acattttttt aaaataaaat gagttttagc aacaatcagg gacaaaacag
    15241 actattgcat gacaaatttc actgtcgcga tttgccccac gtcatccatc accagcaatt
    15301 gataatcacc tttatccgtc aaatgcaggg tcacgttgcg cccgcgttca gttaacggtt
    15361 cgccattcag aaaccaccag cgttcacctg cccctccact tgattgcaac ggcaaagtcg
    15421 cttccgctgc gcccggtaaa cgtttaataa tcgcgccatc gcgaacgcct gtcagctgca
    15481 gcgggagctg ggcatcgtga ccgtatggcg ggcaacttgt cgaggccggt ggtaagcgca
    15541 cagcgcgacg ttctgatgcg ggcagccagg gttccagcgg tagcggccag acatttatca
    15601 tttcttgtcg cgcttgcggg caatcagcgg caacacgttt gccattttca tccagccaga
    15661 tggggaaacg aatgccatta atgccttcct gctccggcag taatagagtt ggcggctgac
    15721 tcccgtccag cagccaggtt gccaggcggc ggcgacagtt accgtcacct tccggcaaag
    15781 actgtccgcc cggccagcag ataacgccac gagtgactga gttcgggcgc gggtcttccg
    15841 gcagattcgc actgcgcgac agtaagatat tattgacctg attcaacaat ggtacggcac
    15901 tggcaaagcc aaactgacca acaacgggcg tgccgtccgg tctgccagtc cagatcccaa
    15961 tgacatagcg agcgttaacc ccaatcgccc aggcgtcacg atagccatag ctggtgcccg
    16021 ttttccatgc cagtggggcg acgcgcggca aggcactatc cggcaagggt tgcgcttcat
    16081 cagccataat ccggcgaatg atccacgccg cccccgacga cattaaaggc cgttcaagca
    16141 gcggatcgtc aggctgtaag cgcaatttgc ctgccttgcc gtggcgagca aacgcggtat
    16201 acgctgccgc catatcttcc agttttgcac cagcgccgcc gagaatgagt gaaagattcg
    16261 gcgcagcacc gttgggcaaa tataacggca atccaacatt gcgtaacttt gccgcaaacc
    16321 gtttcggtcc ataggcttcc agcacctgca cagcaggtaa gttcagcgag cgcaccagcg
    16381 cctcgctcat gctgatcggg ccatgaaaac cgctatcaaa gttacctggt cgataatcac
    16441 cggtgcgccg ggggacgtct tgcagcagtg atgccgggtg gatcaagcct tcatccagcg
    16501 ccagaccata aacaaacggt ttgagcactg atcctggcga tcggatcgaa ttgaccatat
    16561 caacatgacc aaagcgtgaa tcatcgttga gatcaaccga tcccacccag ccgcgaacac
    16621 gcatatcggt atgatcaacc acgatcatcg ccagtgagct gcgcggtggc aaccgccctt
    16681 tccagttttg cgccagttct tccagacgtc gttgaagacc ggcatccaac gtagtagtga
    16741 ttttgtcgct tttgctttta ccgagcatca tgcgcgaaaa cagcggtgcc agttgcggca
    16801 tttgtcgggg ggccagccag atgggttctt cccttgactc ttttacctgc tcacgggacc
    16861 acacaccttg cacggccatc cgttcgagca ctttattacg cgcggcttcg gcacgctccg
    16921 gccaacgatc cgggcgaaga cggctgggcg cttgcggcaa aaccgccagc attgccgcct
    16981 cggaatagct taaattcgca ggcgattttc cgagataagc ccaacttgcc gcaccgatcc
    17041 cctgcaacgt accgccaaac ggagcgcggt taagatacaa ggtcagaatt tcacgcttag
    17101 acagatgcca ttccagttgc aacgcgcgcc agagctggcg aattttgccg ccaaatgttt
    17161 tggggtgagg atcaagcaga cgagcaacct gcatagtgag cgtgctgcca ccggaaataa
    17221 cccgtcccga agtgagatct tgccatgctg cgcgcgccac cgagaatgga ttcacccccg
    17281 gatgcttcca gaaccagcga tcttcataat tgatcagcgc ttcaaggtaa cgtggagaaa
    17341 catcttcgat tgttaccgga taacgccaga tgccgtcagc atcggcgaag cgccagagcg
    17401 gcgtaccatc ctgcgccacg accactcgtg cgggattgac ttcatgcagc ggtagaggcc
    17461 agagtttatc tgctccccac gctgcaagaa aaaggagaaa gggcgcggct gccaacgtta
    17521 tccagcagcc gcgtttggtt aacaagcgag gcatttacgg tctgacaatc agcagatctt
    17581 cagccgcgcc ggtcgcccgc cattggggaa catacattga ttccaccatc ggttgcggta
    17641 cctgatacgt tcccggcgtc accgcccgcg ccagatacac cagcgttacc ggttggtatt
    17701 catcaacggc aaccgccgcc acaaagcgat cgtcacggaa ctcaatgtgc ttaatgctcg
    17761 cctgctgcat ctggttcagt aagttctgca cttcgccacc actttgctcc aggctggcgc
    17821 taccgttcgc cagattctgg ttttccagtt ccagacccgc aggcagcaga tccacgacta
    17881 acgcatccgg cacgctgtta ctggctttta cctgcaacca caccagcacc agatcgccgc
    17941 tacgtaacga gtccagcgat ttgctcttac catcagtacc aagaatatga cgctcgattt
    18001 gcagcacatt gttcgccggt aaaggtgcgg attgcggata accgctggca tccatacgca
    18061 accataacgg ctgatcgcca ctgttgctca cctgcaaggt gacaagttga tcgctattca
    18121 gattgctgtt ttgcgctttc tcgcctgtca gctgctcagc tgagaaagag gtttgcgcct
    18181 gccatttacc gggtaaatcc tgaatcgtac gggcagccag gaacaacgcg ttactttcct
    18241 gcgtcgatag ccagcgttca ccaaacgcct gctgcgaaag tgtgttcagc aaagtgtact
    18301 gctcatcggg tagcagttta ttttcttcca gcaaggagag cattaacgcg ttgtcgcgca
    18361 gtgaactacc gtaatcaccc agccatatcc gctcatcact attacgcggc gttttcagcg
    18421 ccagcgcaat cgcttcttca ccacgcgtcg catcacccat ggttttcagc gcaacgccaa
    18481 gttgcagcag cggtaaacca gaagcggcat ctgcacgatg ctcccagatt tcacgcagcg
    18541 cacccagcgg agccttttgc tgacgggcca acaccagcgc agcgtaagac tgtacggcga
    18601 atttactggc tttgagatta tccgcgtacg ggatcgacat catgcccgga tcttgtaaat
    18661 agcgcagcag acgctcatta ccccggttaa tggcgtctgt cggcacgctg taaccctgtt
    18721 cgcctgcgcg gaccaggaaa tccatcacgt aagccgtcag ccagtactct tcgtcaccgt
    18781 ttttatccca cagcgcaaag ccgccgttat cacgttgcat ttgcagcaaa cgggaaatgc
    18841 cgatatcgac cgatgcacgg cgtttctcat cactgtcgcc tttgatgccc aacgcctgca
    18901 gttgggctgc gttggtataa agtgacggaa acaggccgct ggcggtttgc tcaagacagc
    18961 cgtacggata cgcttttaac tctttgatat aacgtgcgat gttcagcggt ggtttgccgc
    19021 tcaacaacaa ttgcccttcc agcgtaacag gcgagaagtt ttgcaatcca tccgccggaa
    19081 tcgcccatgt ctcaccaggc tgtaacgccg taccgtaatt aaccgtttgt gccgggaacg
    19141 ccggacggac gccgattttc cactgcttat gctgatcggc aacggtttca cccggtaacg
    19201 ctaacccgct aatggtggcc tgaatttctc catcgccata acccggcaat gctcgcaccg
    19261 ggataaacag cgtagtacgc acacctggcg ctaattcaac ggctgcgggt gaatcgctga
    19321 ccagttcaag caaaccactg gcggtcaggg caacgttcag tttttgcggt ttatcggtaa
    19381 gattagtgat atccagcgtc agacgcgagg tatcgccact cgccataaag cgcggcatgt
    19441 tcagttcagc aatcaccggt gcggcaacta tcactttact ttcgttgcta ccgaagtcat
    19501 ctgccgtcca ggcttgcgcc atgacgcgca attcaccgtt aaaatcgcca atcggcagtg
    19561 taaccgagcc ttcgccctgt tcgttgagcg ttaccggcag cgcctgctgc acgacaatat
    19621 tgacgtgatt gaccggcggt ttaccaccac gtttcagctc atcaccatcg ccaccgaaac
    19681 gcagagctgc cagacgcccc tgaccttcaa taacctgacc gtaaatatcg taaatgtctg
    19741 cgccatagcg tttctgacca aagaacgcct gccacggatc tggcgtgacg tagtcagtaa
    19801 tattcagcac accactatca acggcagaca ccagcacatt cacctgttta ggcttctcgc
    19861 catttttagt gctggcttta attttcacgg ttaatggttg attgggacgc atttttgctg
    19921 gtgtttccag cgccagatcg aggcgacggt tttcatcgcc aagcggcaga tgcaacacac
    19981 caaccgcgcg ttttggcgtc gcggagcgag atttatcgcc aggacgtacc accagcgtac
    20041 ttaaatacag atcatgacga ttccaggttt tatcgaccgg aatcgtcaga tccagccctt
    20101 gagcccgaac atcaatctct tgccaccaca gcggcccttc actggactcg accatcgcat
    20161 aacctttacc cgccgttggc gcggcgatat gcaacttaat ggtgtcgcca gggcgataac
    20221 tggctttatc cagtttcagc gtgacacggt cgggtcgcac tgcgccgcta ccgtcgctgt
    20281 tgtcctgcca gctatagcca gcccagaaac gaacactact gaccgcttca ttcggcgctt
    20341 tgacttccag acgataagcg ccccactcta ccggaaaact gaccttgccg gtttcgtccg
    20401 ctttcagatc cagagtttgt tcattttcga tcagatcttt ttgatcaaac tgtgactgcc
    20461 agccttcatc ttctgaccag ttccagtagt aatcgcggcg ttcgcgaatc aggcgcacct
    20521 gcaagcccga cacggctttt ttcacgcctt gcgcatcgct ataaacgatg tcaaaagcgg
    20581 cgttactgcc ttcatcaaca atgggctgtt tcaccgtgct gtcagtacga taatcgtaaa
    20641 ccgatttcga ggcgaactgc ggacggatcc ccggcaatgc atcggcaggc cagatagcct
    20701 gctcagcgcg gcgcgtcacc gggcgaccgc ccgattccag caaactaccc tggaaaataa
    20761 cctgtaatgg ggaatgcgtt tccttccact ggctttctgt agaaacttcg ccgcgccctt
    20821 tatcatccag cgtcaactga acttcatcca gcgtgcggga aagattttcg gcagctatat
    20881 cgccgaattc aaaacaaggt aaggctgaca cagcttcacg cagtgggcgc aggaaaagtt
    20941 gcccttgcaa agtattacca ttagcaggtg caccatacag gtagtacccc accacggaga
    21001 atttcacttc atctttcggc gttagcgggg ttttctcacc ggtcagattc agcgccatgc
    21061 gctctggcat aaaatcttcg acgtggaaat cccacatccg atactgatta tcgcccgtgt
    21121 tagcgcgaat atgccacata ccggttgccg cattgctatc gagtggccag gtaaagtggt
    21181 agaggccatt ctccggctga ctaacgacgc tcctgagtac ctgcccatcg ggtttaatca
    21241 cgtctaactt gatgggttga ttgggcaacg ctttaccgtc tgcatcacgc agcaaaccat
    21301 tgaggattac cgtttcacct gggcgataaa gatcgcgtgg gccaaacatg aaaaactgtt
    21361 tgctatagcc tggcgcgcca gcaatgttaa attctgctaa gtccagcgcc ggaagtttta
    21421 aatcgagtag cgttgtctga ccgtctttac gcgccaacag taatgccgcg tttttatcat
    21481 tttccagctg cacatgcccc tgagcgtcac tggttgcctg agtcagagtc tgccctttct
    21541 catttaataa agagacttca attccttgct gggccgcgcc gttttccaga ctttgggtaa
    21601 agatatccag acgattgtga taacggtgag ctgaaacgcc gatatcactt aacgtaaaca
    21661 gcgtcgcggg attactgtaa tcgtaacgtc cagcctgatt catcacagcc agatacacgc
    21721 ccgcctgctg aagcggtttg atatcgccca gcggcagcaa taatttttca cgggtgttac
    21781 gcgcaggatt gagatcaaac cgtccggtgt agaccagatc cgccatctgc agcagtttgt
    21841 ctgactgcca gttcgccagc gaattgcggt attcccattg gctaatgaat gctggcagag
    21901 attctggctt aacgcggaag aagttaacat cgacattatt aacgttgagc gccattaccg
    21961 gcagcccttc aacgactttg ccaggcagca gcgaaccacg gctggcaaaa ccgacgctgg
    22021 gttggatgtc gcgggtagtt atagtttttt cgtaatcttt actgaaggtt gcgttgttga
    22081 gtgctttgac ctccttgcca atagtaacga tcaaatcacg tttcggttcg aggtggcgta
    22141 aacgtaactc tttaagatta tctgacagct cccaggcacc atccactttg ccgctttttt
    22201 tatcgacgac atgaataacg cgtgagaaat cctgatccgg gtcgagaggg atggagaacg
    22261 tcagcaccag cgtggctgca ccatcaagtt ggacttcaga gagatccagc aatgtcagca
    22321 ccttaccggc actctgttgg gccagttttt gtctctccgg cacggagagt tttgctgaac
    22381 tcgcgttttc tgaagaggcc gctttagtaa cttcagaagg cgcatctttt ttcaccgctg
    22441 ttggcgcgtt atcgttgttg tcgcaccctg ccagcgccag cattagcatg caggcggcta
    22501 cgcgtaactt tttcattttt catccctgcc acaatggccc gttagcaacg tcgaataatt
    22561 attatgcgtg agaatttacg ttatgtaatt cagtatcacg cccatacaat ccgaatttta
    22621 gtgagaattg tggctcagac agccaaatca gcctcttttg cttgtcgctt ttcactaaac
    22681 atccgacaat ttagcctaac cccggcaaaa atggagatgc ctatgtccac gacatggttt
    22741 gtaggagccg actggctcgc cgaacatatt gatgacccgg aaattcagat tatcgatgcc
    22801 cgcatggcgt cgcctggaca ggaggatcgt aacgttgctc aggagtatct gaatggacat
    22861 attcccggcg cagtgttttt tgatatcgaa gcgctttctg atcacacttc cccgcttccg
    22921 cacatgctgc cgcgcccgga aacgttcgcc gtggcgatgc gtgaattagg cgttaaccag
    22981 gataagcacc tgattgtcta tgacgaaggt aatcttttct cagccccacg agcatggtgg
    23041 atgctgcgca cctttggtgt agagaaagtg tcgattctgg ggggtggact tgcaggctgg
    23101 cagcgcgatg atctgctgtt agaagaaggt gcagtagagc tgccggaagg agagtttaac
    23161 gccgcgttta atcctgaagc cgtggtgaaa gtaaccgatg tattattggc aagccatgaa
    23221 aatacggcgc aaattattga tgcccgcccg gctgcacgtt ttaacgcaga agttgatgaa
    23281 cctcgcccag gtttacgtcg cggacatatt cccggagcac tgaatgttcc gtggacggaa
    23341 ctggtgcgcg aaggcgaact aaaaacgacc gatgaactgg atgcgatatt ttttggtcgc
    23401 ggcgtcagct acgacaaacc aattatcgtc agctgcggct ctggtgtaac ggcagccgtg
    23461 gttttgttag cactcgcgac gctggatgtg ccaaacgtga aactgtacga cggcgcatgg
    23521 agtgaatggg gcgcgcgggc agatttaccg gttgagccag tgaaataagt attttacagg
    23581 caataaaaaa ccgccgaatt tggcggtttt ttattgctag tctggttcgc ggcctttcca
    23641 gcaggttgac ttgtgttaca tgagcaacgc aggtgcttca cagcaaaaca atactcacca
    23701 gtaactctct ttttgtcaag caaaagagag taattattgt ttatttagcg tattatcgac
    23761 accggccctt tccgccgtgt tcggtaataa aataacctgg cttattagtc cgaattcaga
    23821 caaatataaa caaatcctgc tcaaaattaa aa
//
LOCUS       DAPHKZ010000066        23729 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.066, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000066 DAPHKZ010000000
VERSION     DAPHKZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23729
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.066"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(318..1454)
                     /locus_tag="RH288_002734"
     CDS             complement(318..1454)
                     /locus_tag="RH288_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDV4031777.1"
                     /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI
                     LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVRYQAR
                     VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
                     ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE
                     QTVIRAPSNGYVTQVLIRPGTYAAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD
                     DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPND
                     DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH"
     gene            complement(1457..1819)
                     /locus_tag="RH288_002735"
     CDS             complement(1457..1819)
                     /locus_tag="RH288_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HDV4031778.1"
                     /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI
                     HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRL
                     EHQLAAEKKTDYSTFPEI"
     gene            2356..4269
                     /gene="mtlA"
                     /locus_tag="RH288_002736"
     CDS             2356..4269
                     /gene="mtlA"
                     /locus_tag="RH288_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDV4031779.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVEALSKM
                     LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL
                     RTSKVKEEDDIEAATRRMQDMKAESKGASPLSAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHTANEEKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA
                     TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGRK"
     gene            4499..5647
                     /gene="mtlD"
                     /locus_tag="RH288_002737"
     CDS             4499..5647
                     /gene="mtlD"
                     /locus_tag="RH288_002737"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDV4031780.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG
                     LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHF
                     RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ"
     gene            5647..6234
                     /gene="mtlR"
                     /locus_tag="RH288_002738"
     CDS             5647..6234
                     /gene="mtlR"
                     /locus_tag="RH288_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HDV4031781.1"
                     /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS
                     FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI
                     NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
                     YAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK"
     gene            complement(6246..6455)
                     /locus_tag="RH288_002739"
     CDS             complement(6246..6455)
                     /locus_tag="RH288_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031782.1"
                     /translation="MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPD
                     ESVPLYLQRLEYYRRLYRPKQVEGQ"
     gene            6740..7102
                     /locus_tag="RH288_002740"
     CDS             6740..7102
                     /locus_tag="RH288_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HDV4031783.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKAT
                     LEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTA
                     LGREMGLQEMTGFSKTAF"
     gene            7474..9129
                     /gene="lldP"
                     /locus_tag="RH288_002741"
     CDS             7474..9129
                     /gene="lldP"
                     /locus_tag="RH288_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDV4031784.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWR
                     GIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFR
                     FGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEW
                     VINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPS
                     DAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLG
                     WLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCIVGVITTLQAYVLTWMIP"
     gene            9129..9905
                     /gene="lldR"
                     /locus_tag="RH288_002742"
     CDS             9129..9905
                     /gene="lldR"
                     /locus_tag="RH288_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HDV4031785.1"
                     /translation="MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVS
                     RNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMADDPDYSFDIL
                     EARYAIEASTAWHAAMRATPGDKEKIQLCFEATLSEDPDIASQADVRFHLAIAEASHN
                     IVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFAGDADGARKAM
                     MAHLSFVHTTMKRFDEDQARHARITRLPGEHNEHSREKNA"
     gene            9902..11092
                     /gene="lldD"
                     /locus_tag="RH288_002743"
     CDS             9902..11092
                     /gene="lldD"
                     /locus_tag="RH288_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent L-lactate dehydrogenase"
                     /protein_id="HDV4031786.1"
                     /translation="MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSE
                     VALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIP
                     FTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLY
                     ALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAK
                     GNAA"
     gene            11290..11763
                     /gene="trmL"
                     /locus_tag="RH288_002744"
     CDS             11290..11763
                     /gene="trmL"
                     /locus_tag="RH288_002744"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDV4031787.1"
                     /translation="MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRD"
     gene            complement(11816..12637)
                     /gene="cysE"
                     /locus_tag="RH288_002745"
     CDS             complement(11816..12637)
                     /gene="cysE"
                     /locus_tag="RH288_002745"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDV4031788.1"
                     /translation="MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI"
     gene            complement(12717..13736)
                     /gene="gpsA"
                     /locus_tag="RH288_002746"
     CDS             complement(12717..13736)
                     /gene="gpsA"
                     /locus_tag="RH288_002746"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDV4031789.1"
                     /translation="MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATL
                     ERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSA
                     QEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKD
                     ERSSH"
     gene            complement(13736..14203)
                     /gene="secB"
                     /locus_tag="RH288_002747"
     CDS             complement(13736..14203)
                     /gene="secB"
                     /locus_tag="RH288_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HDV4031790.1"
                     /translation="MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDL
                     DTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYC
                     PNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(14266..14517)
                     /gene="grxC"
                     /locus_tag="RH288_002748"
     CDS             complement(14266..14517)
                     /gene="grxC"
                     /locus_tag="RH288_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HDV4031791.1"
                     /translation="MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK"
     gene            complement(14659..15090)
                     /locus_tag="RH288_002749"
     CDS             complement(14659..15090)
                     /locus_tag="RH288_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDV4031792.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDG
                     SGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK"
     gene            15335..16879
                     /gene="gpmM"
                     /locus_tag="RH288_002750"
                     /gene_synonym="pgmI"
     CDS             15335..16879
                     /gene="gpmM"
                     /locus_tag="RH288_002750"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDV4031793.1"
                     /translation="MLVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRAFFANPVLTGA
                     VDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKY
                     DTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQ
                     MRDPATGQAHTAHTNLPVPLIYVGDKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            16889..18172
                     /gene="envC"
                     /locus_tag="RH288_002751"
     CDS             16889..18172
                     /gene="envC"
                     /locus_tag="RH288_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HDV4031794.1"
                     /translation="MRGKAINTMTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADE
                     RDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNK
                     QIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALNERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEA
                     TRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            18176..19135
                     /locus_tag="RH288_002752"
     CDS             18176..19135
                     /locus_tag="RH288_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418071.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HDV4031795.1"
                     /translation="MFPFRRNVLAFAALLALSSPVLAGKLAIVIDDFGYRPHNENQVL
                     AMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKNTLRPEMSSDE
                     IERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
                     MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPATVRVL
                     QQMVYNLPPDITLVKASSLLNEPQVDTSTPPKNAVPDAPRNPFRGVKLCKPKKPIEPV
                     YANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKFNASAN"
     gene            complement(19122..20156)
                     /gene="waaH"
                     /locus_tag="RH288_002753"
     CDS             complement(19122..20156)
                     /gene="waaH"
                     /locus_tag="RH288_002753"
                     /EC_number="2.4.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate:LPS(HepIII) glycosyltransferase"
                     /protein_id="HDV4031796.1"
                     /translation="MMNSTNKLSVIIPLYNAGDDFRTCMESLITQTWTALEIIIINDG
                     STDNSVEIAKYYAENYPHVRLLHQANAGASVARNRGIEVATGKYVAFVDADDEVYPTM
                     YETLMTMALEDDLDVAQCNADWCFRETGETWQSIPTDRLRSTGVLTGPDWLRMGLSSR
                     RWTHVVWMGVYRRDVIVKNNIKFIAGLHHQDIVWTTEFMFNALRARYTEQSLYKYYLH
                     NTSVSRLHRQGNKNLNYQRHYIKITRLLEKLNRNYADKIMIYPEFHQQITYEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYKRLITNVRSVKVGYQALLWSFRLWQWRDKTRSHH
                     RITRSAFNLR"
     gene            complement(20395..21420)
                     /gene="tdh"
                     /locus_tag="RH288_002754"
     CDS             complement(20395..21420)
                     /gene="tdh"
                     /locus_tag="RH288_002754"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDV4031797.1"
                     /translation="MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLAAIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKE
                     NLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSG
                     KVILSWD"
     gene            complement(21430..22626)
                     /gene="kbl"
                     /locus_tag="RH288_002755"
     CDS             complement(21430..22626)
                     /gene="kbl"
                     /locus_tag="RH288_002755"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDV4031798.1"
                     /translation="MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPDLIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGM
                     EDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGK
                     QLGVIA"
     gene            complement(22901..23729)
                     /gene="yibB"
                     /locus_tag="RH288_002756"
                     /pseudo
     CDS             complement(22901..23729)
                     /gene="yibB"
                     /locus_tag="RH288_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312523.3"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="protein YibB"
BASE COUNT         5853 a         6208 c         6042 g         5626 t
ORIGIN      
        1 agattaaata ttttttaaat gtgactgtca tccttcagat aataaagcca tcatcgcaat
       61 agatggaaaa gcactcctgc tcttttttga ttagagccgt cgcaggagga acaactcata
      121 tcatcattgc gatctcgacg atgtatagtc tcatcctgcg gcagaacaag acggataaaa
      181 aatccaatga gagcacactc atccagaact tattaacata atgaatatta aagaaaaatc
      241 atcgcagcta atgaagtaat atgcaaaaat aattagtcct tacaaggagc aaagttccat
      301 aatctccccc ctccccctca atgatccaaa taaagataat gcatccagct ggtcattctt
      361 agcagcactt tccgcatcac cgaaacatgg ctgaaatggt cggagtaaac cgccacctgg
      421 gcgtagatgc cgtcgggtaa ggcatcgata tcatcgttag ggtccagttc aatggttccc
      481 agcacaccgt ccgtgccggg cacgaccgtt aatgattgca ataccccctg cgcctgataa
      541 gaaccgcctg gcacgacagg taaaatacta gtcagtttgc cgtgaaacac ctgcccaggt
      601 agcgcgttaa acaccacttc cgcatcatcg ccgggtttca gacgtaacag cgagttttgc
      661 cgaaattggg cgacaatttg ccgtttttgc tcggggatga agaccatcac cggacgcagc
      721 ggcaaggcag ctgcgtatgt acctgggcgg atcagtacct gagtaacgta gccattgctc
      781 ggcgcgcgaa tgacagtctg ctcaaggtta tattttgctt cagtaagttg cgctcttaag
      841 ctcacaatct gcgattgctc gccgttaacc atactgtcga gctggctctg gatctgcgcc
      901 tgctccgcca ccgagccttt caccagcgca tcctgcgcga ggaaattttg ccgcgcatcg
      961 tcgatgtcac gttccgagaa cggattcacc gccgcctggc tgcctttcaa gtaacgttga
     1021 taatttttaa acagacggtc gcgctccgct gaaacctggg tggtgttggc ctgcgcttca
     1081 gtgagctgcg cacgcagcgt ctttatatta tgcgtcgccg tcatcaggtc agcctgaagt
     1141 ctgtcaactc gcgcctggta acgaaccggg tcgagcttaa aaagcacctc gcccttttga
     1201 ataagctgat tattcttgtc agtgacttca gtaacaattc ccgtcacctg tggcgtgata
     1261 gggatcgcta tcactgcctt ttgcgcggta aaagtgtaag ggtggttgta gttcatcaac
     1321 aaaatcaaac cactcaccag aaacacgcct cccagcgccg ccgtcgccag cgtccactga
     1381 tttaccggaa tgcggaagat tttaaagacc gcccacgcca gcgccacgta agttaaaaca
     1441 atcaatagat ccataattag atctccggga acgtggaata gtcagtcttt ttctcggcgg
     1501 cgagttgatg ctccagccgg gaaattcggt cagaaagtgc ggcgatttcc gggtcagtcg
     1561 ctttctcctg cgacgcaaca tgtgactgca taccccagcc acgctccggt tgatagagcg
     1621 tcgcccagat ccacagaaac ggccagataa catgcagagt aaacaggctc acccagcccg
     1681 ccgtatgaat agcgtcggca tggggatggt tgcgcttttt ggcaatcaga taagggatgt
     1741 catgtatcgc gatgattcca taaaaaatca ccagaaagac gaagatcagc actcccaacg
     1801 cgaaatagtt tagaaacata tctgcctcgg attcacgttt atcagtgttg tttttgggct
     1861 ggcagccaga agggagtcag gctgatattt tgacaataat ccgggttcgc gattctcgcc
     1921 ataacaccaa agaataattt ttagaggtga tgagttgctt agttacataa cgattgtatg
     1981 acgaaggcat aacatgctgt agatcacatc aggtgaacgc cgtaagaaaa tatcttgtga
     2041 ttcagatcac aaagattcaa caaaccatca aaacaaaaat gtgacactac tcacatttaa
     2101 atgccatttt tagcgaaaat cgccgccttg ttgctttttt acacaagcgt tttgtgatga
     2161 acgtcacgtc aattacctct ctacccccta tatttatgtg attgatatca cacaaaaggc
     2221 cgtcgactgg acagttaacc gattcagtgc cagatttcgc agtatctaca aggtccggct
     2281 acctctgccg ccacattaac aaaaaacctc gggcttccag cctgcgcgac agcaaacata
     2341 agaaggggtg tttttatgtc atccgatatt aagatcaaag tgcaaagctt tggtcgtttc
     2401 ctcagcaaca tggtgatgcc aaatatcggc gcgtttatcg cgtggggtat catcaccgcg
     2461 ttatttattc caacagggtg gttaccgaac gagacgctgg cgaagctggt cgggccgatg
     2521 atcacttatc tcctgccgct gctgatcggt tataccggtg gtaagctggt aggcggcgaa
     2581 cgtggcggcg tagtcggtgc catcaccacc atgggcgtta tcgtcggcgc agacatgccg
     2641 atgttcctcg gttctatgat tgcaggtccg ctgggcggct ggtgcattaa gcacttcgac
     2701 cgctgggtag acggtaagat caaatccggt tttgagatgc tggtgaataa cttctccgca
     2761 ggcatcatcg ggatgatcct cgctattctg gcattcctcg gcattggccc gattgttgaa
     2821 gccctgtcca aaatgctggc tgcgggcgtt aacttcatgg ttgtccatga catgctgccg
     2881 ctggcgtcta tctttgttga accggcgaaa atcctgttcc tcaacaacgc cattaaccac
     2941 ggtatcttct cgccgctggg tattcagcag tcccatgaac tgggtaaatc aatcttcttc
     3001 ctgattgaag ctaacccagg tccaggtatg ggcgtgctgc tggcgtacat gttctttggt
     3061 cgtggtagcg ctaaacagtc tgcgggcggt gcggcaatca tccacttcct ggggggtatc
     3121 cacgaaatct acttcccgta tgtgctgatg aatccgcgtc tgatcctcgc agtcatcctc
     3181 ggcggtatga ctggcgtgtt cacgctgact atcctgggcg gtggtctggt ttctccggca
     3241 tctccgggtt ctatccttgc tgtactggcg atgacaccaa aaggtgctta cttcgctaac
     3301 atcgcgggtg tgtgtgcggc gatggctgtc tccttcgttg tctctgctat tttgctgaga
     3361 accagcaaag tgaaagaaga agatgatatt gaagcagcaa ctcgtcgtat gcaggacatg
     3421 aaagctgagt ctaaaggcgc atctccgctg tctgctggcg atgtgactaa cgacctgagc
     3481 cacgtacgta aaatcatcgt tgcctgtgac gccggtatgg gttccagtgc gatgggcgca
     3541 ggcgttctgc gtaagaaaat tcaggatgca ggtctgtcgc agatttctgt tactaacagc
     3601 gcgatcaaca acctgccgcc agatgtggac ctcgtcatca ctcaccgtga cctgaccgaa
     3661 cgcgctatgc gccaggttcc gcaggcacag catatttcgc tgaccaactt cctcgacagc
     3721 ggcctgtaca ccagcctgac cgaacgtctg gttgctgccc aacgccacac ggcaaacgaa
     3781 gagaaagtaa aagacagcct gaaagacagc tttgacgatt ccagtgctaa cctgttcaag
     3841 ctaggcgcgg agaacatctt cctcggtcgc aaagcggcaa ccaaagaaga agcgattcgt
     3901 tttgctggcg agcagctggt gaaaggcggt tacgttgagc cggaatacgt tcaggcgatg
     3961 ctggatcgtg aaaaactgac cccgacttat ctgggtgagt ctatcgcggt gccacacggt
     4021 acggttgaag cgaaagatcg cgtactgaaa acgggcgtcg tgttctgcca gtacccggaa
     4081 ggcgtgcgct tcggtgaaga agaagatgac attgcccgtc tggtgattgg tattgctgcc
     4141 cgtaacaacg agcacattca ggttatcacc agcctgacca atgcactgga tgatgagtcc
     4201 gtcatcgagc gtctggcaca caccaccagc gtggatgaag tgctggaact gctggcaggt
     4261 cgtaagtaat ccaatcccac cctctccaca tggagaaggt ggggttaatt gcctgatgcg
     4321 ctacgcttat caggcctaca ggatgcatca caatttgttg aatttgcacg ttcttgtagg
     4381 ccggataagg cgcttacgcc gcatccggcg ctgcccctct cctcacggag agggtttggg
     4441 tgagggtaaa gcctcacccc agccctctcg ggtaaaaaca ttgatgaagg ttaatactat
     4501 gaaagcatta cattttggcg caggtaatat cggtcgtggc tttatcggta aactgctggc
     4561 agacgcgggt atccaactga cgtttgccga tgtcaatcag gtggtacttg atgccctgaa
     4621 tgcccgtcat agctatcagg tacatgtggt tggtgaaacc gagcaggtag ataccgtttc
     4681 cggcgtcaat gctgtcagca gcattggtga tgatgtcgtt gatctgattg ctcaggttga
     4741 tttagtcact accgccgttg gcccggttgt gctggaacgt attgctccgg caatcgccaa
     4801 agggctggtg aaacgtaaag aacaaggtaa tgaatccccg ctgaacatca tcgcctgtga
     4861 aaacatggta cgcggtacca cgcagctgaa aggccatgtg atgaacgccc tgccggaaga
     4921 cgccaaagcg tgggtagaag aacacgttgg ctttgtcgat tccgccgttg accgcatcgt
     4981 accgccttcg gcttcggcaa ctaacgatcc gctggaagtg acggtagaaa ccttcagcga
     5041 atggattgtc gataaaacgc agttcaaagg cgcactgccg aacatcccag gcatggagtt
     5101 aaccgacaac ctgatggcat ttgtcgaacg taaactcttc accctgaaca cgggtcatgc
     5161 tataaccgcg tacctcggaa aactggccgg tcatcagacc attcgtgacg cgattctcga
     5221 cgagaaaatc cgcgcggtgg taaaaggtgc gatggaagaa agtggtgcag tattgatcaa
     5281 gcgctacggc tttgacgctg acaagcatgc ggcgtacatc cagaaaattc tcggccgttt
     5341 tgagaacccg tatctgaaag atgatgtaga gcgcgtaggc cgtcagccac tgcgtaaact
     5401 gagtgctggc gaccgtctga tcaagccact gctcggtacg ctggaatatg gtctgccaca
     5461 taaaaacctg attgaaggta ttgccgctgc aatgcacttc cgcagtgaag atgatccgca
     5521 ggctcaggaa ctggcagcac tgatcgctga caaaggtccg caggcggcgc tggcacagat
     5581 ttccggtctt gatgccaaca gcgaggttgt atccgaggcg gtaaccgctt ataaagcaat
     5641 gcaataatgg tggaccaggc gcaggacacc ctgcgcccga ataacagatt gtcagatatg
     5701 caggcaacaa tggaacaaac ccaggccttt gaaaaccgtg tgcttgagcg tctgaatgct
     5761 ggcaaaaccg tgcgaagctt tctgatcacc gccgtcgagc tcctgaccga ggcggtaaat
     5821 cttctggtgc ttcaggtatt ccgcaaagac gattacgcgg tgaagtatgc tgtagaaccg
     5881 ttactcgacg gcgatggtcc gctgggcgat ctttctgtgc gtttaaaact catttacggg
     5941 ttgggcgtca ttaaccgcca ggaatacgaa gatgcggaac tgctgatggc attgcgtgaa
     6001 gagctaaatc acgacggcaa cgagtacgcc tttaccgacg acgaaatcct tggacccttt
     6061 ggtgaactgc actgcgtggc ggcgttacca ccgccgccac agtttgaacc agcagactcc
     6121 agtttgtatg caatgcaaat tcagcgctat caacaggctg tgcgatcaac aatggtcctt
     6181 tcactgactg agctgatttc caaaatcagc ttaaaaaaag cctttcaaaa gtaagcaacg
     6241 tctgcttact gcccctctac ctgcttcggc cgataaagcc gacgataata ctccagacgt
     6301 tgtagatata acggcacgct ttcatcgggt attccggacg gaatcgcgtt acggggagga
     6361 agttttttca gatactcccg gaacgcctgg cttgatgcca tgaaatctac ggctttatcg
     6421 ataagaagcg gaacgttttc acctaatttg cccatgatga tatctccgta ttaccccgcg
     6481 ccgggaatgc gcggccgcca attttagttt aggttcccgg taaagatgac attaaggaaa
     6541 acgtgctgaa tcctcaataa tcatccgctg ctgtttatta tcttttttct atagatttct
     6601 taattaatca acgaattgcg tagtttttga gcatgttaat gattacgtta cagaactatt
     6661 acaatgtcat tagttgtgaa caaagcacct ggtcgcgcat actaggggct ataaatttat
     6721 ctttatcaga agccatcaca tgaaagaagt cgaaaaaaac gaaatcaaac gtctcagcga
     6781 tcgcctggac gccatccgcc accagcaggc cgatctttcg ctggttgaag ccgcagacaa
     6841 atatgccgag ctggaaaaag agaaagccac gctggaagca gaaattgctc gcctgcgtga
     6901 agttcatagc caaaaactga gtaaagaagc acagaagctg atgaagatgc cattccagcg
     6961 cgcaattacc aaaaaagagc aggctgatat gggcaagctg aagaaaagtg ttcgcggact
     7021 ggtcgttgtg cacccaatga ccgcactggg ccgcgaaatg ggcctgcagg agatgactgg
     7081 gttttcaaag accgcgtttt aagaacacag tatctacagg gtgattctgc acattcctat
     7141 aggccgagta aggtgttcac gccgcatccg gcaagataag gcgctctgga tcaacaacct
     7201 aagggcaatt ctctgatgag gattgccctt ttctttacca gacatctccc cccacaagaa
     7261 ttggccctac caattcttcg cttatctgac ctctggttca caatttccca attaaaactc
     7321 acatcaatgt tgccaataca taacgtttag ttaaccattc attgtcatta tccctacaca
     7381 acacaattgg cagtgccact tttacacaac gtgtgacaag gagatgagca acagactcat
     7441 tacacgatgt gcgtggactc caggagacct gcaatgaatc tctggcaaca aaactacgat
     7501 cccgccggga atatctggct ttccagtctg atagcatcgc ttcccatcct gtttttcttc
     7561 tttgcgctga ttaagctcaa actgaaagga tacgtcgccg cctcgtggac ggtggcaatc
     7621 gcccttgccg tggctttgct gttctataaa atgccggtcg ctaacgcgct ggcctcggtg
     7681 gtttatggtt tcttctacgg gttgtggccc atcgcgtgga tcattattgc agcggtgttc
     7741 gtctataaga tctcggtgaa aaccgggcag tttgacatca ttcgctcgtc tattctttcg
     7801 ataacccctg accagcgtct gcaaatgctg atcgtcggtt tctgtttcgg cgcgttcctt
     7861 gaaggagccg caggctttgg cgcaccggta gcaattaccg ccgcattgct ggtcggcctg
     7921 ggttttaaac cgctgtacgc cgccgggctg tgcctgattg ttaacaccgc gccagtggca
     7981 tttggtgcga tgggcattcc aatcctggtt gccggacagg taacaggtat cgacagcttt
     8041 gagattggtc agatggtggg gcggcagcta ccgtttatga ccattatcgt gctgttctgg
     8101 atcatggcga ttatggacgg ctggcgcggt atcaaagaga cgtggcctgc ggtcgtggtt
     8161 gcgggcggct cgtttgccat cgctcagtac cttagctcta acttcattgg gccggagctg
     8221 ccggacatta tctcttcgct ggtatcactg ctctgcctga cgctgttcct caaacgctgg
     8281 cagccagtgc gtgtattccg ttttggtgat ttgggggcgt cacaggttga tatgacgctg
     8341 gcccacaccg gttacactgc gggtcaggtg ttacgtgcct ggacaccgtt cctgttcctg
     8401 acagctaccg taacactgtg gagtatcccg ccgtttaaag ccctgttcgc atcgggtggc
     8461 gcgctgtatg agtgggtgat caatattccg gtgccgtacc tcgataaact ggttgcccgt
     8521 atgccgccag tggtcagcga ggctacagcc tatgccgccg tgtttaagtt tgactggttc
     8581 tctgccaccg gcaccgccat tctgtttgct gcactgctct cgattgtctg gctgaagatg
     8641 aaaccgtctg acgctatcag caccttcggc agcacgctga aagaactggc tctgcccatc
     8701 tactccatcg gtatggtgct ggcattcgcc tttatttcga actattccgg actgtcatca
     8761 acactggcgc tggcactggc gcacaccggt catgcattca ccttcttctc gccgttcctc
     8821 ggctggctgg gggtattcct gaccgggtcg gatacctcat ctaacgccct gttcgccgcg
     8881 ctgcaagcca ccgcagcaca acaaattggc gtctctgatc tgttgctggt tgccgccaat
     8941 accaccggtg gcgtcaccgg taagatgatc tccccgcaat ctatcgctat cgcctgtgcg
     9001 gcggtaggcc tggtgggcaa agagtctgat ttgttccgct ttactgtcaa acacagcctg
     9061 atcttcacct gtatagtggg cgtgatcacc acgcttcagg cttatgtctt aacgtggatg
     9121 attccttaat gattgtttta cccagacgcc tgtcagacga ggttgccgat cgtgtgcggg
     9181 cgctgattga tgaaaaaaac ctggaagcgg gcatgaagtt gcccgctgag cgccaactgg
     9241 cgatgcaact cggcgtatca cgtaattcac tgcgcgaggc gctggcaaaa ctggtgagtg
     9301 aaggcgtgct gctcagtcga cgcggcggcg ggacgtttat tcgctggcgt catgacacat
     9361 ggtcggagca aaacatcgtc cagccgctaa aaacactgat ggccgatgat ccggattaca
     9421 gtttcgatat tctggaagcc cgctacgcca ttgaagccag caccgcatgg catgcggcaa
     9481 tgcgcgccac acctggcgac aaagaaaaga ttcagctttg ctttgaagca acgctaagtg
     9541 aagacccgga tatcgcctca caagcggacg ttcgttttca tctggcgatt gccgaagcct
     9601 cacataacat cgtgctgctg caaaccatgc gcggtttctt cgatgtcctg caatcctcag
     9661 tgaagcatag ccgtcagcgg atgtatctgg tgccaccggt tttttcacaa ctgaccgaac
     9721 aacatcaggc tgtcattgac gccatttttg ccggtgatgc tgacggggcg cgtaaagcaa
     9781 tgatggcgca ccttagtttt gttcacacca ccatgaaacg attcgatgaa gatcaggctc
     9841 gccacgcacg gattacccgc ctgcccggtg agcataatga gcattcgagg gagaaaaacg
     9901 catgattatt tccgcagcca gcgattatcg cgccgcagcg caacgcattc tgccgccgtt
     9961 cctgttccac tatatggatg gtggtgcata ttctgaatac acgctgcgcc gcaacgtgga
    10021 agatttgtca gaagtggcgc tgcgccagcg tattctgaaa aacatgtccg acttaagcct
    10081 ggaaacgacg ctgtttaatg agaaattgtc gatgccggtg gcactggctc cggtgggttt
    10141 gtgtggcatg tatgcgcgtc gtggcgaagt tcaggcagcc aaagcggcgg acgcgcatgg
    10201 tattccgttt actctctcga cggtttccgt ttgcccgatt gaagaagtcg cgccagccat
    10261 caagcgccca atgtggttcc agctttatgt actgcgcgat cgcggcttta tgcgtaacgc
    10321 gctggagcga gcaaaagcag cgggttgttc gacgctggtt ttcaccgtgg atatgccgac
    10381 accgggcgca cgctaccgtg atgcgcattc aggtatgagc ggcccgaacg cggcaatgcg
    10441 ccgctacttg caagcggtga cacatccgca atgggcgtgg gatgtgggcc tgaacggtcg
    10501 tccacatgat ttaggtaata tctcagctta tctcggcaaa ccgaccggac tggaagatta
    10561 catcggctgg ctggggaata acttcgatcc gtccatctca tggaaagacc ttgaatggat
    10621 ccgcgatttc tgggatggcc cgatggtgat caaagggatc ctcgatccgg aagatgcgcg
    10681 cgatgcagta cgttttggtg ctgatggaat tgtggtttct aaccacggtg gccgccagct
    10741 ggacggtgta ctctcttccg cccgtgcact gcctgctatt gcagatgcgg tgaaaggtga
    10801 tatagccatt ctggcggata gcggaattcg taacgggctt gatgtcgtgc gtatgattgc
    10861 gctcggtgcc gacaccgtac tgctgggtcg tgctttcttg tatgcgctgg caacagcggg
    10921 ccaggcgggt gtagctaacc tgctaaatct gatcgaaaaa gagatgaaag tggcgatgac
    10981 gctgactggc gcgaaatcga tcagcgaaat tacgcaagat tcgctggtgc aggggctggg
    11041 taaagagttg cctgcggcac tggctcccat ggcgaaaggg aatgcggcat agtcgtttgc
    11101 gccccctcac cctaaccctc tccctcaggg agaggggacc gttcggcgct gtatgtactc
    11161 cctcactctg aaacgacacc gcactctttt tttctccctc gcccctccgg ggagagggcc
    11221 ggggtgaggg gaaaaggccg cactgctcac caattttctg ctatcctgcc cccgcactaa
    11281 gggggcagta tgctaaacat cgtactttac gaaccagaaa ttccgccaaa tactggcaac
    11341 atcatccgtc tttgcgctaa taccggcttt cgtctgcata tcatcgaacc gatgggattt
    11401 gcctgggacg ataagcgcct gcgccgcgcg gggctggact atcacgagtt taccgccgtt
    11461 acgcgtcatc atgactatcg cgcgttcctc gaagcagaaa atccccagcg cctgttcgcc
    11521 ctcaccacga aaggtacacc tgctcacagc gccgtaagct atcaggatgg cgattatctg
    11581 atgttcggcc cggaaacacg cggcctgcca gcgagcattc ttgatgccct gcccgctgaa
    11641 caaaaaattc gcattccgat ggtgccggac agccgcagca tgaatctgtc caatgcggtg
    11701 tcggtagtgg tgtatgaagc ctggcggcag ttggggtatc cgggagcggt attgagagat
    11761 tagttactgt aggccggata gatgattaca tcgcatccgg cacgatcaca ggacattaga
    11821 tcccatcccc atactcaaat gtatggttaa taccgttgaa atgctggtcc atatccattg
    11881 atggcttatc gctgtctggt ttaccgacaa tacgagccgg aacgccagcg gcggtggtat
    11941 gcggcggcac cggttgcagc accacggaac ctgcgccaat cttcgcgccg cgcccaactt
    12001 caatattgcc gaggattttc gcgcccgcgc caatcatcac accttcacga attttcgggt
    12061 gacggtcacc accagattta cccgtaccgc caagcgtcac agattgcaga atcgatacgt
    12121 cgttttcaat caccgccgtt tcaccaacga cgatgcctgt cgcgtggtca agcatgatac
    12181 cgcgaccaat ttttgctgcc gggtgaatat cgacctggaa cgtcacagaa acctggtttt
    12241 gcagaaagat tgccagtgcg cgacgcccct gattccacaa ccagtgaccg atgcgatagg
    12301 cctgcaaggc atgaaaaccc ttcaggtata acaacggggt tgagtattta tcgactgccg
    12361 ggtcgcgggt acgcaccgcc tgaatatcac aggccgcaga ggcgatcatt tccgggtcag
    12421 cggcgtaggc ttcttccacc acttcacgga tagcaatagc aggcataatt ggcgatgaca
    12481 gcttgttcgc cagcatgtag ctcagtgcac tgccaaggtt ttcgtgcttg agtagcgtcg
    12541 cgtggtaaaa actggccagc attggctcac agtccgccag cgttctggct tcggctttaa
    12601 tattgttcca gacaatttcc agttcttcac acgacattgc ttactccaca cgatgagata
    12661 atgaccggcc cgttctgcgc gggccgggtc atagcggtaa caaaggttcc ctggggttag
    12721 tggctgctgc gctcgtcctt gcgtgcacga cctagtaaag tcaatgctgc ctcgcgcgcg
    12781 ttttttccgc aatataatac ttgataaatt tcctcggtta ttggcatttc aacgccgaag
    12841 cgatgcgcca gttcgcggac ttctttcgta ttgcggtagc cttccaccac ctgaccaatc
    12901 ttctcctgcg cgctttgtac atccatgccc tgaccgagca tcatgccaaa acggcggtta
    12961 cgcgactggt tgtcggtaca ggtaagcacc agatcgccaa gccccgccat gcccataaag
    13021 gtggcagggt cggcacccag cgccgcacca agacgcgaca tttcagccag cccacgggtg
    13081 atcagcgccg tacgcgcatt cgcaccaaaa ccgataccgt cggacatccc cgcaccaatg
    13141 gcaataacgt ttttcaccgc gccgccaagc tgcacgccaa tgaaatccgg attgctgtaa
    13201 acgcggaaac ttttgccgca gtgcagcagc tgctggagat catcggcaaa ggtctgatcg
    13261 gtcgaggcca gcgaaatagc tgtcggtaaa cctgccgcca gttctttcgc aaacgttggg
    13321 ccagagataa ccgccagcgg aatttgatcg cctaaggcct cacgcgccac gtcctgtaac
    13381 agacgtccgg tttccgcttc cagccctttg gtcgcccaca ccagacgcgc atcaggacgc
    13441 atcagtggtt taatctggcg cagcacttca ccaaagacat ggctgggtac gacgacgaga
    13501 atattacggc tggctgccag cgcagtggcg agatcgcttt caagatggag cgtatcggga
    13561 aaaggcacat cggggagaaa cgcggcgtta cagcggtcgc gttcaagcgt tgcgatatgt
    13621 tcagggtcat ggccccagag gacaacctcg tggccatttc ttgccagggt gatggcaaga
    13681 gcggtgccgt acgagccggc accgatcaca gtcattgaag cattacgttg gttcatcagg
    13741 catcctgatg ttcttcagta ccttcgccag cctgctgctg caaatagttc atgaacagcg
    13801 catcgaagtt aaccggcgca aggttcagtt gcgggaatgt accgcgggat accatgctgg
    13861 tgatgcactc acgagcatac gggaacagaa tgttcgggca gtatgctccc aggcaatgcg
    13921 ccatctgggt gccttcgata cccgcgatgg agaaaatacc gccctgctga acttcacaca
    13981 ggaacgcggt ttcttcgccc aaagaggccg ttacggtaac acgcagtacc acttcgtata
    14041 cgtcatctgc cagttgggaa gatgccgtat ccagatcaag tttaacttct ggttgccaat
    14101 ctttctggaa aacgtgcggc gcgttcggcg cttcgaaaga gatatccttg gtataaatac
    14161 gttggatctg gaaagtcatt tcagtgttgt tttgttctga catgtgtaga aaacccttaa
    14221 gtgttgtcct taaatactgc gcaatgtaat gccaacgttc acacgttatt tcagcagggg
    14281 atccagtcca ccacgtgcat ccaatgcata caagtcatca cagccgccaa tgtgctgtgc
    14341 gtcaataaaa atctggggaa ccgtggtgcg accgctgcgt ttgatcatct cttcacgctt
    14401 ggcggcgttg ccatcgatcg gcagctcctg gaaactcacg cccttgctgc tcagcagtgc
    14461 ttttgcacga tggcaatacg ggcaggtttc tttggtatag atttcaacat tggccataaa
    14521 ttagctcctg tttttttacc ctgaaatttc atgttgcagg gcggcagcaa aatggagtgt
    14581 ccccagaagc ttataacaat aagtcgctgg gggcctaatt gcagctaacg gcctgcatca
    14641 tgaaagacga caggtaaatt atttgccgcg caccaaaggc aagttttcgc cagcccagcc
    14701 agcgacgcct tctttcagca cgaatacttg cgcaaaacca gctttcgtca gtgcgtttgc
    14761 aggctcctgg cactgcatgc cagaaccgtc taccacgata accggtttgt ctttgtgctt
    14821 ctcaagctca ccaacattgt tggctttgat ttcgctcggc aacagattaa tagaacctgc
    14881 gatatggcct ttacggaagt catcacgctg acgtaaatcc acaaccacag cgtcttcttt
    14941 gttgatcaga cgcgtagctt caccacgagt aatcaccttc actttcgagg tcaggctctt
    15001 aaacgtagtc acaagaaccg ccaccagtaa cgcgatccag gcgatactca gtatgggatg
    15061 acggccaaca aattgcataa tttcttgcat ggggggtaac aactcccgac gtagtgatta
    15121 aaaaaaccag gaaaggagta tacctgcgcg gtgcggcaaa tacagccagc gcgttaactg
    15181 gaatgcaatt ttgcggggcg cgacgaaaaa aaagcgtaaa tctggcatcg gcttgccgcg
    15241 agcggtcgta tattttgatc ttcagaggct attttatcga ttcagctgta gtaaaattac
    15301 gcaaattttg actcttgagt atgaggttgt cgcaatgttg gtttctaaaa aacctatggt
    15361 actggtgatt ctggatggct atggctatcg cgaagaacag caggataacg ccatttttag
    15421 tgctaaaacc ccggtaatgg atgcactgtg ggccaatcgt ccgcataccc taatcgacgc
    15481 ttccggtctg gaagtcggtc tgcctgaccg tcagatgggt aactccgaag taggccacgt
    15541 taacctgggt gccggccgca tcgtgtatca ggacctgact cgtctggacg ttgaaatcaa
    15601 agatcgcgct ttctttgcta atccggtgct gactggcgcg gtagataaag cgaaaaacgc
    15661 aggcaaagcg gtacacatta tgggtctgct ctccgcaggc ggcgtacaca gccacgaaga
    15721 tcacatcatg gcgatggtag aactggcagc tgaacgcggc gcagaaaaaa tctacctgca
    15781 cgcattcctt gacggtcgcg acactccgcc gcgcagtgct gaatcctcgc tgaaaaaatt
    15841 cgaagaaaaa tttgccgcgc tgggcaaagg ccgcgtagcg tccatcattg gtcgttacta
    15901 cgcgatggac cgcgataacc gttgggatcg cgtagaaaaa gcttatgacc tgctgactct
    15961 ggcgcagggc gagttccagg ccgataccgc cgttgctggt ttgcaggctg cttatgctcg
    16021 cgacgaaaat gatgaattcg tgaaagcgac cgttatccgt gctgaaggtc agccagacgc
    16081 ggcaatggaa gacggcgatg cactgatttt catgaacttc cgtgctgacc gcgcgcgtga
    16141 aatcactcgt gctttcgtga acgctgattt cgatggcttc gcgcgtaaga aagtggttaa
    16201 cgtcgatttc gtgatgctga ccgaatacgc cgctgacatc aaaactgcgg ttgcttaccc
    16261 acccgcttcc ctggttaaca ccttcggcga gtggatggcg aaaaacgaca aaactcagtt
    16321 gcgtatttcc gaaaccgaaa aatatgccca cgttactttc ttcttcaacg gtggcgtaga
    16381 agagtcgttc aaaggcgaag atcgcattct gatcaactca ccgaaagtgg ctacctacga
    16441 tctgcaaccg gaaatgagct ccgcagagct gaccgaaaaa ctggttgcgg ccatcaagag
    16501 cggcaaatac gacaccatca tctgtaacta tccgaacggc gacatggtag gtcacaccgg
    16561 ggtgatggaa gcggcggtta aagcggttga agcgctggat cactgcgtgg aagaagtcgc
    16621 gaaagcggtt gagtccgtgg gtggacaact gctgatcacc gctgaccacg gtaacgctga
    16681 gcagatgcgc gatccggcaa cgggtcaggc acacacggca cacaccaacc tgccagttcc
    16741 gctgatttac gttggtgata agaacgtgaa agcggttgaa ggcggcaaac tttctgacat
    16801 cgcgccgacc atgttgtcgc tgatgggtat ggaaatcccg caagagatga ctggtaagcc
    16861 gctgttcatc gtggaataat ccctccccat gaggggaaag gcgattaata ccatgacacg
    16921 ggccgtgaaa ccgcgcaggt ttgcaatcag gcccatcatc tacgccagcg ttcttagcgc
    16981 tggcgtattg ttgtgcgcct tttccgccca cgcggatgag cgtgaccaac tcaaatctat
    17041 tcaggctgac atcgccgcaa aagagcgcgc ggtacgccaa aagcaacaac aacgcgcaag
    17101 cctgctcgca caattgaaaa agcaggaaga agcgatctct gaagccaccc gtaagctgcg
    17161 cgaaacgcaa aacacgctca atcaactcaa taaacagatt gatgagatga acgcgtcgat
    17221 tgccaaactg gagcagcaaa aagccgccca ggagcgcagc ctcgccgcac aactggatgc
    17281 cgcattccgt cagggcgagc ataccggtat tcagctgatt ctcagcggtg aagaaagcca
    17341 gcgtggacag cgtttacagg cttatttcgg ctatctcaac caggcgcgac aagaaaccat
    17401 tgcccagttg aagcaaacgc gtgaagaagt cgccatgcag cgtgctgaac tggaagagaa
    17461 acagagcgag caacaaacgc tgttatatga gcagcgcgcc caacaggcga aactgactca
    17521 ggcgctgaac gagcgtaaaa agacgctggc agggctggag tcttccatcc agcaaggtca
    17581 gcaacagttg agcgagctgc gcgccaacga atcccgtctg cgtaacagca ttgcccgtgc
    17641 ggaagccgcg gcgaaagcgc gtgcagaacg agaagcacgt gaggcccagg cggttcgcga
    17701 ccgccagaaa gaagcgacgc gcaaaggcac cacctacaaa ccgaccgaaa gcgaaaaatc
    17761 gctgatgtcc cgtaccggtg gtctgggcgc gccgcgtggt caggcattct ggccggttcg
    17821 cgggccgacg ctgcatcgct atggcgaaca gctacagggt gaattacgct ggaaaggtat
    17881 ggttatcggt gcttctgaag gtactgaagt taaagcgatt gccgacggtc gggtgattct
    17941 ggctgactgg ctgcaaggct acggtctggt ggtggtggtt gagcatggta aaggcgacat
    18001 gagtctttac ggctataatc agagcgcact ggtgagcgtt ggttcgcagg ttcgcgcggg
    18061 ccagccgatt gcactggtgg gcagcagtgg cggtcagggt cggccttcac tctatttcga
    18121 aattcgccgc cagggtcagg cggtcaatcc acagccgtgg ttgggaagat aagttttgtt
    18181 tccatttcgt cgtaacgttc ttgcatttgc cgctctgttg gcgctctcct cccccgtact
    18241 tgctggcaaa cttgccatcg tcattgatga ttttgggtat cgcccgcaca acgaaaacca
    18301 ggtgctggcg atgccttccg ctatctccgt cgctgtatta cccgattcac cgcacgccag
    18361 agagatggcg accaaagcgc ataacagcgg gcacgaagtg ttgattcatc tcccgatggc
    18421 accgttgagt aaacagccgc tggagaaaaa tacgctacgc ccggagatga gcagcgacga
    18481 aattgagcgc attattcgta gtgcggtcaa taacgtgccc tatgccgtgg ggatcaacaa
    18541 ccacatgggc agcaagatga cctctaacct gtttggtatg cagaaagtga tgcaggcgct
    18601 ggagcgttac aatctttact tcctcgacag cgtaaccatc ggtaataccc aggcgatgcg
    18661 cgccgcgcaa ggcactggcg tgaaggtgat caaacggaag gtattcctcg acgattcgca
    18721 aaatgaagcg gacatccgtg tgcaatttaa tcgcgcaatt gacctggcgc gtcgcaacgg
    18781 ttcgaccatt gccattgggc atcctcaccc tgcaacggta cgcgtgttgc aacagatggt
    18841 ttataacctg ccgccagaca ttacgctggt gaaagccagc agcttgctga atgaaccgca
    18901 ggttgatact tctacaccgc cgaaaaacgc tgtgcctgat gcaccgcgta atccgttccg
    18961 tggcgtgaag ctgtgcaaac cgaagaaacc gatagaacct gtttatgcta atcgcttctt
    19021 tgaagtatta agcgaaagca tcagccagag cacgctgatc gtttacttcc agcatcagtg
    19081 gcaaggctgg ggcaaacagc ccgaagcggc gaagtttaac gctagcgcaa attaaaggcg
    19141 ctacgcgtaa tgcgatggtg cgaccgcgtt ttgtcgcgcc attgccataa gcggaaagac
    19201 cacagtaacg cctggtaacc gaccttcacg ctgcgcacat tggtaatcag gcgcttatac
    19261 ataccggaag taaatatctc ggcaatcatc cgttggcggg taagaatatc cggctctttg
    19321 cgcaccgcat ggcaaacacg caatgcctcg taagttattt gctgatgaaa ttccggataa
    19381 atcataattt tgtcggcata atttcgattt aatttctcca gcaggcgggt aatcttaata
    19441 tagtgacgtt gataattaag gtttttattc ccttgtctat gcaaccgact cactgacgta
    19501 ttatgcagat aatatttata taatgattgc tcggtatatc gcgcacgcag cgcgttaaac
    19561 atgaattctg ttgtccagac aatatcctga tgatgtaatc cggcaataaa tttaatgtta
    19621 tttttaacaa taacatcacg gcgataaacc cccatccaga caacgtgagt ccaacggcgc
    19681 gaagaaagcc ccatccgcag ccagtccggg ccggttaata cgccggttga gcgaaggcga
    19741 tcggtgggga tggattgcca ggtttctccc gtttcacgaa aacaccagtc agcgttgcac
    19801 tgcgccacgt cgaggtcgtc ctctaacgcc atggtcatca gcgtttcgta catggtggga
    19861 tagacttcat cgtcagcatc gacaaaagcg acatatttgc ccgttgccac ttcaatccca
    19921 cgattacgcg ccaccgatgc gccagcattc gcctgatgca acaaacgaac gtgcggatag
    19981 ttttctgcgt aatactttgc tatttcaaca gaattatccg ttgaaccatc gttaataata
    20041 atgatttcca gagcagtcca ggtttgcgta attaaagatt ccatacaagt gcggaaatca
    20101 tcgcccgcat tatataacgg aataataaca ctaagtttat tggtgctgtt catcataaat
    20161 taccgacgac ctctgaagtt atcctgacgt tttacaggct ttgtattaag aaactattaa
    20221 gcctgtgaga tattattttt acaggtgaga gagtcacttc agggtagaga gataatgaga
    20281 gcagctatat aagagatcag cacaattacg aactctttat tacactgaca ggattttaca
    20341 tatttaacag attatcctca gataaaaggg ctggaatacc agcccttgtt cgtgttaatc
    20401 ccagctcaga ataactttcc cggactggcc cgaacgcata gcgtcaaagc ccttctggaa
    20461 atcatcgata gagaaacgat gggtaatgat cggcgaaaga tcgaggccag actgaatcag
    20521 cgccgccatc ttgtaccagg tttcaaacat ctcacgaccg taaatacctt taatgaacaa
    20581 gcctttaaag atcactttgg tccagtcgat agacatatca gacggcggaa tacccagcat
    20641 cgcaatacgg ccgccgtggt tcatggtgtc aagcatggta cgaaacgctg gcggcgcacc
    20701 ggacatttcc agaccgacat caaaaccttc ggtcatgcct aactccgcca tcacgtcatt
    20761 gagattttct ttggcgacgt taaccgcacg ggtgataccc attttacgcg ccagctcaag
    20821 gcggtattcg ttaacatcag tgatcaccac attgcgtgca ccaacgtgtt tcgccaccgc
    20881 cgctgccata ataccaatcg ggcctgcacc agaaaccagc acatcttcgc ccaccagatc
    20941 aaacgacagc gcggtatgca cggcgttacc gaagggatca aaaattgcgg ctaagtcatc
    21001 ggaaatattg tcggggattt tgaaggcgtt gaatgccggg atcaccagat attcggcaaa
    21061 gcagcccggg cgattaacac caacgcctat cgtgttgcgg cacaaatggg tacgaccacc
    21121 acgacagttg cggcaatgac cacaggtgat atggccttcg ccagaaacgc gatcgccgat
    21181 cttgaagcct ttcacttcct gaccaatacc taccacttca ccgacatatt catggcccac
    21241 gaccatcggc accgggatgg ttttttgcga ccactcatcc cagttataga tgtgaacgtc
    21301 agtcccgcag atggctgttt tacggatttt aatcagcaga tcgttatgcc cgagttccgg
    21361 tacaggaacg tcggtcatcc agatgccctc ttccgctttc agtttggata acgctttcat
    21421 ctcacatcct caggcgataa cgcccagttg tttaccaata cgcgtaaatg cttctactgc
    21481 acgcgtaatt tgctcagggg tatgcgccgc agacatctgg gtacgaatac gcgcctgacc
    21541 tttcggaacg accggataga agaaaccggt aacgtaaatg ccctcttttt gcagctcacg
    21601 ggcaaatttc tgcgccacta ccgcatcacc aagcatgacc ggaataatgg cgtgatcggc
    21661 tcccgccagg gtaaagcccg ccgccgacat ttgctcacgg aactgacgcg cgttcgccca
    21721 cagacggtca cgcagttcgc tgcccgcttc gaccatctcc agtactttga tggacgcggc
    21781 aacaatggcc ggtgccagcg agttggagaa caggtacgga cgagaacgct ggcgcagcca
    21841 ctcaaccact tctttgcgcg ccgcggtata accaccagaa gccccgccca gcgctttacc
    21901 aagcgtaccg gtgataatat cgacccggcc catcacatcg cagtattcat gggaaccacg
    21961 accattttca ccgacaaaac cgaccgcgtg ggagtcgtct accatcacca gggcatcata
    22021 tttatctgcc agatcgcaaa cgcccttcag gttggcaatc acgccgtcca ttgagaacac
    22081 accatcggtg gcgatcagca catgacgcgc accggcttca cgcgcttctt tcagacgtgc
    22141 ttccagctcc tgcatatcgt tgttggcata gcgatagcgt ttagctttgc acagacgcac
    22201 accatcaata atagacgcgt ggttcagtgc gtcggagata atggcgtctt ccgcacccag
    22261 aagcgtttca aacaggccac cgttagcatc aaagcaggaa gagtagagaa tcgcatcttc
    22321 catccccagg aaggccgcca gtttttgttc aagctcttta tggctgtcct gagtgccgca
    22381 aataaaacgc accgaagcca tgccgaaacc gtgagaatcc attcccgcct ttgccgccgc
    22441 aatcagatca ggatgattcg ccagcccgag atagttgttg gcacaaaagt taatgacgtg
    22501 gcttccatca gccacagtga tatctgcttg ctgcgcagac gtaataatgc gctcttcttt
    22561 aaacaaccct tccgcccgtg cggtttccag atcgttggtt aactgctgat aaaattctcc
    22621 acgcattgcg attctccaga cagggcaaat tccagcacat attacccaaa cttataggtc
    22681 gcgacgagat aacgcgttaa cacttctgca aaattcagga taaataacgt gtaacttgat
    22741 gtctctcaac acctacagat agtagaaaaa ctgtacagtt ttggctgggc ataatgatga
    22801 ttgattttac tgcattgata taaaaagaaa aaatgatgcc aaagcatcat ttttcctatc
    22861 tcagttggta tcaaaacgct acccactaat ggagggaaac ctattttctt gaaaggaaaa
    22921 ttctcagcgc ctgcattttt gcccctaaag tgttactcct gaagcagcga aacaaatcga
    22981 accattttcc tctccccaga tagtttaggt tgaagagatc ggggcgtttg taatagcaca
    23041 tgacaaaaat gccctggtca tcgtccacaa tgttattatt tagtgttatt ttttgacttt
    23101 ccagaactaa tttatagaat tctttccatt tatgctgtga accaacaatt gcgcccccaa
    23161 taatatatac atgattgcca atcatgaaat caaaaacctg ttgttgagat gtgacagtaa
    23221 gccctttttt atagtgaaaa gatgcatctt actttcatca aatgggaaat cccaaatttt
    23281 caatcctcga gttacatttg gcttacggca atagccaaaa tctatccacg caacaagagg
    23341 cgttttcact aagcccatgt tgatagcttt atttacaaaa taggccttaa ggttacatac
    23401 caaaacatac tctggtgacc agtactctgg gttttttaat tgtcgaggct caagtctatt
    23461 tgtaaacgac tcatcttttt gaattttttc gatacgactt ctgatatatc taaatttctt
    23521 ttttatatcg ataacgataa ccgttgttgg ttttccgttg cgaatcgctt caacccttgg
    23581 tttcaaatcg ggagaagtga aaataatcat ctcattttca agtgcggcca gacgctcaaa
    23641 gtaactaaaa taaacatcaa ctgaacgagc tagtttttca cggaaccctt tattagcagt
    23701 ccaatcccct ctaccaatgt caaaatatg
//
LOCUS       DAPHKZ010000067        23587 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.067, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000067 DAPHKZ010000000
VERSION     DAPHKZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23587
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.067"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(372..716)
                     /locus_tag="RH288_002757"
     CDS             complement(372..716)
                     /locus_tag="RH288_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416323.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDV4031799.1"
                     /translation="MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
     gene            848..2758
                     /locus_tag="RH288_002758"
     CDS             848..2758
                     /locus_tag="RH288_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDV4031800.1"
                     /translation="MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVE
                     AGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKG
                     RSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADKVVKESGFGELIPE
                     ADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSW
                     IFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSSR"
     gene            2816..3511
                     /gene="tsaB"
                     /locus_tag="RH288_002759"
     CDS             2816..3511
                     /gene="tsaB"
                     /locus_tag="RH288_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDV4031801.1"
                     /translation="MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQD
                     ILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGA
                     WRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPEIVHERMQQLSGEW
                     VTVGTGWQAWPDLGKESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYL
                     RNNVAWKKLPGKE"
     gene            3551..4132
                     /gene="yeaY"
                     /locus_tag="RH288_002760"
     CDS             3551..4132
                     /gene="yeaY"
                     /locus_tag="RH288_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein YeaY"
                     /protein_id="HDV4031802.1"
                     /translation="MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRV
                     MSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADVN
                     GFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQVTGYKRWHLTQQVIMPPQPI
                     DPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE"
     gene            4337..6022
                     /gene="fadD"
                     /locus_tag="RH288_002761"
     CDS             4337..6022
                     /gene="fadD"
                     /locus_tag="RH288_002761"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HDV4031803.1"
                     /translation="MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSL
                     TEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA"
     gene            6104..7219
                     /gene="rnd"
                     /locus_tag="RH288_002762"
     CDS             6104..7219
                     /gene="rnd"
                     /locus_tag="RH288_002762"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707318.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HDV4031804.1"
                     /translation="MITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFD
                     GEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQIL
                     AAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITA
                     KLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLAD
                     WRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVE
                     KAQTLPEDALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLL
                     NWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ"
     gene            complement(7273..8238)
                     /gene="yeaX"
                     /locus_tag="RH288_002763"
     CDS             complement(7273..8238)
                     /gene="yeaX"
                     /locus_tag="RH288_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaX"
                     /protein_id="HDV4031805.1"
                     /translation="MSDYQMFEVQVSQVEPLTEQVKRFTLVATDGKPLPAFTGGSHVI
                     VQMSDGDNQYSNAYSLLSSPHDTSCYQIAVRLEENSRGGSRFLHQQVKVGDRLTISTP
                     NNLFALIPSARKHLFIAGGIGITPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELV
                     QHPQAEKVHLHHSSTGTRLELARLLADIEPGTHVYTCGPEALIEAVRSEAARLDIAAD
                     TLHFEQFAIEDKTGDAFTLVLARSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCG
                     TCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLDL"
     gene            complement(8294..9418)
                     /gene="yeaW"
                     /locus_tag="RH288_002764"
     CDS             complement(8294..9418)
                     /gene="yeaW"
                     /locus_tag="RH288_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaW"
                     /protein_id="HDV4031806.1"
                     /translation="MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFA
                     KSWICVAHSSELANANDYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGK
                     AKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPN
                     ATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPG
                     FSDSVQVDRYWHTMHGNWTLQYGFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPI
                     KGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQK
                     GLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD"
     gene            complement(9450..10931)
                     /gene="yeaV"
                     /locus_tag="RH288_002765"
                     /pseudo
     CDS             complement(9450..10931)
                     /gene="yeaV"
                     /locus_tag="RH288_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310537.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter YeaV"
     gene            complement(11086..12171)
                     /gene="dmlA"
                     /locus_tag="RH288_002766"
     CDS             complement(11086..12171)
                     /gene="dmlA"
                     /locus_tag="RH288_002766"
                     /EC_number="1.1.1.83"
                     /EC_number="1.1.1.85"
                     /EC_number="1.1.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional
                     D-malate/3-isopropylmalate/tartarate dehydrogenase"
                     /protein_id="HDV4031807.1"
                     /translation="MMKTMRIAAIPGDGIGKEVLPEGIRVLQAAAERWGFALSFEQME
                     WASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWPDTVPDHISLWGSLLKFRREFDQ
                     YVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQES
                     VFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEIRW
                     DKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTFP
                     SLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQAHNGILAAIEEVIA
                     HGPKTPDMKGNATTPQVADAICKIILR"
     gene            12274..13197
                     /gene="dmlR"
                     /locus_tag="RH288_002767"
     CDS             12274..13197
                     /gene="dmlR"
                     /locus_tag="RH288_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310535.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DmlR"
                     /protein_id="HDV4031808.1"
                     /translation="MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLE
                     QTLNVVLLHRTTRRVTITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISS
                     FGFGRQVVAPALSALAKAYPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARK
                     LATNYRILCASPEFIAQHGAPKHLTDLSALPCLVIKERDHPFGVWQLRNKEGPHAIKV
                     TGLLSSNHGEIVHQWCLDGQGIALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVS
                     RLATSAKVRITVEFLRQYFAEHYPNFSLEHA"
     gene            13324..13962
                     /gene="leuE"
                     /locus_tag="RH288_002768"
     CDS             13324..13962
                     /gene="leuE"
                     /locus_tag="RH288_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HDV4031809.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGY
                     LAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGK
                     NSEAKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILAATL
                     ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS"
     gene            14135..14494
                     /gene="yeaR"
                     /locus_tag="RH288_002769"
     CDS             14135..14494
                     /gene="yeaR"
                     /locus_tag="RH288_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HDV4031810.1"
                     /translation="MLQIPQNYIHTRSTPFWNKQTAPAGIFERHLDKGTRPGVYPRLS
                     VMHGAVKYLGYADEHSAEPDQVILIEAGQFAVFPPEKWHNIEAMTDDTYFNIDFFVAP
                     EVLMEGAQQRKVIHNGK"
     gene            14498..14680
                     /locus_tag="RH288_002770"
     CDS             14498..14680
                     /locus_tag="RH288_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HDV4031811.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETETPMTLLVPEVAAEVIKDLVN
                     TVRSYDTENEHDVCGW"
     gene            14828..15076
                     /locus_tag="RH288_002771"
     CDS             14828..15076
                     /locus_tag="RH288_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDV4031812.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGG
                     WISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKIKS"
     gene            complement(15135..15209)
                     /gene="yoaJ"
                     /locus_tag="RH288_002772"
     CDS             complement(15135..15209)
                     /gene="yoaJ"
                     /locus_tag="RH288_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaJ"
                     /protein_id="HDV4031813.1"
                     /translation="MKKTTIIMMGVAIIVVLGTELGWW"
     gene            complement(15212..15310)
                     /locus_tag="RH288_002773"
     CDS             complement(15212..15310)
                     /locus_tag="RH288_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HDV4031814.1"
                     /translation="MRIGIIFPVVIFITAVVFLAWFFIGGYAAPGA"
     gene            complement(15343..16368)
                     /gene="dgcP"
                     /locus_tag="RH288_002774"
     CDS             complement(15343..16368)
                     /gene="dgcP"
                     /locus_tag="RH288_002774"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416308.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcP"
                     /protein_id="HDV4031815.1"
                     /translation="MSDQIIARVSQSLAKEQSLESLVRQLLEMLEMVTDMESTYLTKV
                     DVEARLQHIMFARNSQKMYIPENFTVSWDYSLCKRAIDENCFFSDEVPDRWGDCIAAR
                     NLGITTFLSTPIHLPDGSFYGTLCAASSEKRQWSERAEQVLQLFAGLIAQYIQKEALV
                     EQLREANAALIAQSYTDSLTGLPNRRAIFENLTTLFSLARHLNHKIMIAFIDLDNFKL
                     INDRFGHNSGDLFLIQVGERLNTLQQNGEVIGRLGGDEFLVVSLNNENADISSLRERI
                     QQQIRGEYHLGDVDLYYPGASLGIVEVDPETTDADSALHAADIAMYQEKKHKQKTPFV
                     AHPALHS"
     gene            16551..16805
                     /gene="yoaF"
                     /locus_tag="RH288_002775"
     CDS             16551..16805
                     /gene="yoaF"
                     /locus_tag="RH288_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing lipoprotein YoaF"
                     /protein_id="HDV4031816.1"
                     /translation="MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVYCQQK
                     GGTLIPVQTAQGVSNNCKLPGGETIDEWALWRRDHPAGEK"
     gene            complement(16827..17174)
                     /locus_tag="RH288_002776"
     CDS             complement(16827..17174)
                     /locus_tag="RH288_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416306.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDV4031817.1"
                     /translation="MNIQCKRVYDPAEQSDGYRILVDRLWPRGIKKTDLALDEWDKEI
                     TPSTELRKAFHGEVVDYATFREQYLAELAQHEQEGKRLADIAKKQPLTLLYSAKNTTQ
                     NHALVLADWLRSL"
     gene            complement(17229..18410)
                     /gene="nimT"
                     /locus_tag="RH288_002777"
     CDS             complement(17229..18410)
                     /gene="nimT"
                     /locus_tag="RH288_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-nitroimidazole transporter"
                     /protein_id="HDV4031818.1"
                     /translation="MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAY
                     SLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPY
                     LLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
                     LNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTL
                     FLGINSLVYYVIIGWLPAILISHGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQ
                     RGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPLMGKIHDANGNWSVPLMGVAILSLLMAIFGLCAGRDKEI
                     R"
     gene            18507..19328
                     /gene="nimR"
                     /locus_tag="RH288_002778"
     CDS             18507..19328
                     /gene="nimR"
                     /locus_tag="RH288_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NimR"
                     /protein_id="HDV4031819.1"
                     /translation="MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLI
                     LALHGAITCTVENALWMVPPQYAVWIPGGVEHSNQVTANAELCFLFIEPSAVTMPTTC
                     CTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKI
                     RTMVEMMAKGPVEWGALGQWAGFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQG
                     LVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIARLTTVSPQSAKPDPRQ"
     gene            complement(19285..19731)
                     /locus_tag="RH288_002779"
     CDS             complement(19285..19731)
                     /locus_tag="RH288_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDV4031820.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFP
                     WIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRG
                     VTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            19901..20005
                     /locus_tag="RH288_002780"
     CDS             19901..20005
                     /locus_tag="RH288_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416302.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031821.1"
                     /translation="MNDQMFVETLIITSSFFAIAVVLVLSVLLIERTG"
     gene            complement(20006..20509)
                     /gene="yeaK"
                     /locus_tag="RH288_002781"
     CDS             complement(20006..20509)
                     /gene="yeaK"
                     /locus_tag="RH288_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mischarged aminoacyl-tRNA deacylase"
                     /protein_id="HDV4031822.1"
                     /translation="MTEMAKGSVTHQRLIALLSQEGADFRVVTHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHIGGLRASLASPAEVDEL
                     TGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTADYLRIAQPEL
                     VNFRRTA"
     gene            complement(20552..22042)
                     /locus_tag="RH288_002782"
     CDS             complement(20552..22042)
                     /locus_tag="RH288_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDV4031823.1"
                     /translation="MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQ
                     KADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTAHK
                     YPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
                     NDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQN
                     VMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIII
                     NQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHF
                     RLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDT
                     LGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRL
                     QHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS"
     gene            complement(22223..23566)
                     /locus_tag="RH288_002783"
     CDS             complement(22223..23566)
                     /locus_tag="RH288_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310521.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDV4031824.1"
                     /translation="MVSMGTQKLKAQSFFIFSLLLTLILFCITTLYNENTNVKLIPQM
                     NYLMVVVALFFLNAVIFLFMLMKYFTNKQILPTLILSLAFLSGLIYLVETIVIIHKPI
                     NGSTLIQTKSNDVSIFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPF
                     LVFPLLAHNLSSYNADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRL
                     ASELWPLIALLCLASLCCNLLLLTLDEYNYTIWYISRGIEVSSKLFVVSFLIYNIFQE
                     LQLSSKLAVHDVLTNIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQFKRINAQWGHR
                     VGDKVLVSIVDIIQQSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLT
                     GFSNRYDVPEQMTISIGTVFSTGDTRNISLVMTEADKALREAKSEGGNKVIIHHI"
BASE COUNT         6136 a         5685 c         5975 g         5791 t
ORIGIN      
        1 taatttgcat ctaatatcaa agggattata acgatatggc acgagttaac ctgttgacat
       61 tcaggtgttt taaaggtagc agctcatggt gtgttatcca gtaagatgga gaaatttaac
      121 ggtcagtccg cacgctataa ccagattgtt cagctaagaa agaaaaccag agttgctaat
      181 caaagggcga acacaacggc atgtttatgt ttatttatat agttagtttt atagataaaa
      241 ttgaaattat aaatataaat aatgaattag cagaagcatc aacagtaata tcttattctc
      301 tggtcgattt atgtaaaacc gaccagtatt atcgataaat tatcgtctga cttattttgc
      361 ttcgataaag cttacaccgc agccacaatc ttaatttcaa ctttatactt cgggttcatc
      421 aaacccgctt gtaccgtgca gcgcaccggc gcatgacccg cgacaaccca ggcatcccac
      481 gctttattca tcgccgcgaa gtcgttttta tcggccagga aaatggtggc atccagaatg
      541 ctcgatttat tgctgccctg tttttccagc acggcgtcaa tctgtgccag cgtgttggcg
      601 gtttgctcaa aggcatcggc gtcgaggttt tccggtacac cagtgtagta gagcgtgttg
      661 ttgtggatta ctacatcaga ccagcgggct tcagcatcga tacgaacgat agtcatcatt
      721 ttgtcctcat tatacttcca ttttcgtgct gcaaagactg ccacaatgtg aggtcgccgt
      781 caccacttca actggcgaaa gcgccctcat cctgacataa tccctgttca aatcaacagg
      841 gggtagtgtg acggacgatt ttgcaccaga cggtcagctg gcgaaagcga taccaggctt
      901 taagccgcga gaaccacagc gacagatggc ggtagccgtc acccaggcga tagaaaaagg
      961 ccagccgctg gtggtggaag caggaaccgg tacgggcaaa acctacgctt acctggctcc
     1021 tgcgctgcgg gcgaaaaaga aagtcattat ctcgaccggc tcaaaagcgt tgcaggatca
     1081 gctctacagc cgcgatttgc caacagtctc aaaggcattg aaatatacgg gcaacgtggc
     1141 gctgctgaaa gggcgctcaa actacctctg cctcgaacgt ctcgaacagc aggcgctggc
     1201 ggggggcgat ctgccggtac aaatcttaag cgatgtgatc ctgctgcgct cctggtctaa
     1261 tcaaacagtc gatggtgata tcagcacctg cgtcagcgtg gcggaagatt cacaggcgtg
     1321 gccgctggtc accagcacca acgacaactg tcttggcagc gactgcccga tgtataaaga
     1381 ttgctttgtg gtcaaagcac gtaaaaaagc gatggacgcc gatgtggtgg tggtaaacca
     1441 tcatctcttt ctggcggata aggtggttaa agagagtgga tttggcgaac tgatcccgga
     1501 agcggacgtc atgatcttcg acgaagccca ccagctaccg gacattgcca gccagtattt
     1561 tggtcagtca ctctccagtc gacaactgct cgacctggca aaagacatca ccatcgccta
     1621 ccgcaccgaa ttaaaagaca cccagcagtt acaaaagtgc gctgatcgtc ttgcccagag
     1681 tgcgcaggat tttcgtctgc aactcggtga gccaggttat cgcggtaacc tgcgtgagct
     1741 gttagctaat ccgcaaattc agcgggcatt tttactgctc gatgacaccc tggaactttg
     1801 ttatgacgtg gcgaaactgt cactggggcg ttccgccttg ctggatgcgg catttgagcg
     1861 cgccacgttg tatcgcacac ggctgaagcg gctaaaagag atcaatcagc cgggctacag
     1921 ctactggtac gaatgcactt cgcgccattt tactctggct ctcacgccgc tcagcgtggc
     1981 ggataaattc aaagagttaa tggcgcaaaa acccggtagc tggatcttca cctcagcaac
     2041 gctgtcggtg aacgacgatc tgcatcattt cacctcgcgg cttggcatcg aacaggccga
     2101 gtcgttgctg ttgcccagcc catttgatta cagccgccag gcgttactct gtgtgccgcg
     2161 caatctgccg caaaccaacc agccaggttc tgctcgccag ttagcggcaa tgctgcgacc
     2221 gatcatcgaa gctaacaacg gtcgttgttt tatgctttgt acctcgcacg ccatgatgcg
     2281 cgatctggcc gagcagttcc gcgctaccat gacgcttcct gtattgttgc agggggaaac
     2341 cagcaaaggg caactgttgc agcaatttgt cagcgccggt aatgcgcttc ttgtggcaac
     2401 cagcagtttc tgggaagggg tggacgtgcg tggcgataca ttgtcattgg taattatcga
     2461 caaattgccg tttacctcgc cggatgatcc actgttaaaa gcgcgcatgg aagattgtcg
     2521 tttgcgcggt ggcgacccgt tcgatgaagt gcaactacca gatgccgtca ttactctcaa
     2581 acagggggta gggcgactga ttcgcgacgc cgacgatcgt ggcgtgctgg tgatttgtga
     2641 caatcggctg gtgatgcgtc cttacggcgc gacgtttctc gccagtctgc cgcccgcgcc
     2701 acgcacccgt gacattgccc gtgcggttcg tttccttgcg ataccatcct ccaggtaatt
     2761 tgttacggag tatggtatga tgcgcgcctt tttattgatc taagcacgaa gacccatgcg
     2821 aattctggct atcgataccg cgacagaggc ctgctctgtc gccctgtgga acgacggtac
     2881 tgtcaacgct cattttgagc tttgccctcg tgaacatact caacgaatct taccgatggt
     2941 gcaggatatc ctgaccacca gcggaacttc cctgactgat attaacgctc tggcttacgg
     3001 gcgcggcccc ggtagcttta ctggcgtgcg cattggtatt ggcatcgcgc aagggctggc
     3061 gcttggcgcg gaattaccga tgattggcgt ctccacgcta atgacgatgg cgcaaggggc
     3121 gtggcgcaaa aacggcgcaa cccgcgtgct ggcagccatt gacgcgcgaa tgggcgaagt
     3181 ttactgggcc gaatatcagc gtgatgaaaa cggtatctgg cacggtgaag aaaccgaagc
     3241 cgtactcaaa cccgaaatcg tccatgaacg aatgcaacag ctttccggcg aatgggtgac
     3301 ggtagggacg ggctggcaag cttggccgga tctcggtaaa gagagcgggc tggttttgcg
     3361 cgatggcgaa gtgttactgc ctgctgctga agatatgctg ccgattgcgt gtcagatgtt
     3421 tgctgagggt aaaacggtgg cggtggaaca tgccgaaccg gtttatttac gtaacaacgt
     3481 cgcatggaag aaacttccgg gcaaagaatg aatcttaaga gtatgccctg agaaaaaaag
     3541 gagtcgcacc atggcggttc aaaagaatgt tatcaaaggc atactggcag gtacgtttgc
     3601 gctaatgctg agcggttgtg tcactgtgcc ggacgccatt aaaggcagca gtcccacgcc
     3661 gcaacaagat ttagttcggg tgatgagtgc gccgcagctg tacgttggtc aggaggcacg
     3721 ctttggtggc aaagtggttg cggtacaaaa ccagcaaggg aaaactcgcc tggaaattgc
     3781 taccgtaccg ctggacagcg gagccagacc gacgctggga gaaccttctc gcggtcgcat
     3841 ttatgccgat gtgaacggtt ttctggaccc ggtggatttc cgtggacaac tggttacggt
     3901 agtcgggcca atcactggtg cggttgacgg caaaatcggc aatacgccct ataaatttat
     3961 ggtgatgcaa gtaacgggtt acaaacgttg gcatttaacc cagcaggtga ttatgccgcc
     4021 tcagccgatt gatccatggt tttatggcgg tcgtggctgg ccctatggct acggcggatg
     4081 gggctggtat aatcccggcc ccgcgagagt acaaacagtt gtaactgaat aattacttgt
     4141 ttttaaagaa aaagaaacag cggctggtcc gctgtttctg cattcttacg gtaaagataa
     4201 aaataaatag tgacgcgctt cgcaaccttt tcgttgggta attatcaagc tggtatgatg
     4261 agttaatatt atgttaacgg catgtatatc atttggggtt gcgatgacga cgaacacgca
     4321 ttttagaggt gaagaattga agaaggtttg gcttaaccgt tatcccgcgg acgttccgac
     4381 ggagatcaac cctgaccgtt atcaatctct ggtagatatg tttgagcagt cggtcgcgcg
     4441 ctacgccgat caacctgcgt ttgtgaatat gggggaggta atgaccttcc gcaagctgga
     4501 agaacgcagt cgcgcgtttg ccgcttattt gcaacaaggg ttggggctga agaaaggcga
     4561 tcgcgttgcg ttgatgatgc ctaatttatt gcaatatccg gtggcgctgt ttggcatttt
     4621 gcgtgccggg atgatcgtcg taaacgttaa cccgttgtat accccgcgtg agcttgagca
     4681 tcagcttaac gatagcggcg catcggcgat tgttatcgtg tctaactttg ctcacacact
     4741 ggaaaaagtg gttgataaaa ccgccgttca gcacgtaatt ctgacccgta tgggcgatca
     4801 gctatctacg gcaaaaggca cggtagtcaa tttcgttgtt aaatacatca agcgtttggt
     4861 gccgaaatac catctgccag atgccatttc atttcgtagc gcactgcata acggctaccg
     4921 gatgcagtac gtcaaacccg aactggtgcc ggaagattta gcttttctgc aatacaccgg
     4981 cggcaccact ggtgtggcga aaggcgcgat gctgactcac cgcaatatgc tggcgaacct
     5041 ggaacaggtt aacgcgacct atggtccgct gttgcatccg ggcaaagagc tggtggtgac
     5101 ggcgctgccg ctgtatcaca tttttgccct gaccattaac tgcctgctgt ttatcgaact
     5161 gggtgggcag aacctgctta tcactaaccc gcgcgatatt ccagggttgg taaaagagtt
     5221 agcgaaatat ccgtttaccg ctatcacggg cgttaacacc ttgttcaatg cgttgctgaa
     5281 caataaagag ttccagcagc tggatttctc cagtctgcat ctttccgcag gcggtgggat
     5341 gccagtgcag caagtggtgg cagagcgttg ggtgaaactg accggacagt atctgctgga
     5401 aggctatggc cttaccgagt gtgcgccgct ggtcagcgtt aacccatatg atattgatta
     5461 tcatagtggt agcatcggtt tgccggtgcc gtcgacggaa gccaaactgg tggatgatga
     5521 tgataatgaa gtaccaccag gtcaaccggg tgagctttgt gtcaaaggac cgcaggtgat
     5581 gctgggttac tggcagcgtc ccgatgctac cgatgaaatc atcaaaaatg gctggttaca
     5641 caccggcgac atcgcggtaa tggatgaaga aggattcctg cgcattgtcg atcgtaaaaa
     5701 agacatgatt ctggtttccg gttttaacgt ctatcccaac gagattgaag atgtcgtcat
     5761 gcagcatcct ggcgtacagg aagtcgcggc tgttggcgta ccttccggct ccagtggtga
     5821 agcggtgaaa atcttcgtag tgaaaaaaga tccatcgctt accgaagagt cactggtgac
     5881 tttttgccgc cgtcagctca cgggatacaa agtaccgaag ctggtggagt ttcgtgatga
     5941 gttaccgaaa tctaacgtcg gaaaaatttt gcgacgagaa ttacgtgacg aagcgcgcgg
     6001 caaagtggac aataaagcct gagcgttaag tcagtcgtca gacgccggtt aatccggcgt
     6061 tttttttgac gcccactaaa gagaaaacaa tttgaattac caaatgatta ccacggacga
     6121 tgcgctggct tctttgtgtg aagccgtccg tgcctttccg gcgatagccc tggatactga
     6181 atttgttcgt acgcgcactt attacccgca gctggggttg attcaacttt tcgatggcga
     6241 gcatctggcg ctaatcgatc cactcgggat caccgactgg tcaccgctga aagcgatcct
     6301 gcgcgatccg tccatcacaa aatttctcca tgcaggcagt gaagatctgg aagtgttcct
     6361 caatgtcttt ggcgaattac cacaaccctt gattgacacg caaatccttg ctgccttctg
     6421 cggacgcccg atgtcatggg gtttcgcttc catggtggaa gagtattccg gcgttacgct
     6481 ggacaagagt gaatcgcgca ccgactggct ggccagaccg ctgaccgaac gtcagtgtga
     6541 atacgcagcg gcggatgtct ggtatctgtt accgatcacc gccaagctta tggtagaaac
     6601 ggaggcctcc ggctggctac ctgcggcgct ggatgaatgc cgcctgatgc aaatgcgtcg
     6661 tcaggaagtc gttgcgccgg aagatgcctg gcgtgatatc accaatgcct ggcaattacg
     6721 cacacgccaa ctggcctgtc tgcaactgtt agccgactgg cgactgcgca aggcgcgaga
     6781 gcgcgatctg gcggtgaact ttgtcgtgcg tgaagagcat ttgtggtcgg tagcgcgtta
     6841 tatgccggga agtttaggcg aactggacag cctgggttta tccggtagcg aaatccgctt
     6901 tcacggtaaa acgctgctag cgctggtgga aaaagcgcag acattgccgg aagatgcctt
     6961 accgcagccg atgcttaacc tgatggacat gccgggttat cgtaaagcgt ttaaagcgat
     7021 taagtcgctg attactgacg tgagcgaaac gcataagatc agcgccgaat tgctggcatc
     7081 gcgtcggcaa atcaaccaac tgctgaactg gcactggaaa ctgaaaccgc agaacaattt
     7141 gccggagctg atttccggct ggcgtggtga gctgatggcg gaagcattac acaatttatt
     7201 gcaggaatat ccgcagtaaa atcttccgaa gccggactgg gcgcgctcag cgccacatcc
     7261 ggcttcggca aactacaaat ccaacaccag gcgtttaccc ttcgcacgcg aacaacagat
     7321 caacatactt tgctggctgg cacgctcttc atcgctaaaa tattgatccc gatggtcagc
     7381 ttcaccttcc agtattgctg tttcgcaggt tccgcatacc ccttcacgac ataaacattc
     7441 cactttcgca gctttattat tttcaataac ctgcaaaata gtcatctctt ccggcaccac
     7501 aaactctttt ccggaacggg caagcaccag ggtaaatgca tcgccggttt tgtcttcgat
     7561 agcaaattgc tcaaagtgca gcgtatcggc ggcgatgtcc agacgcgcag cttcacttct
     7621 taccgcttca attagcgcct cggggccaca ggtataaacg tgtgtgccag gttcgatatc
     7681 cgccaataat cgcgctaatt ccagtcgtgt tccggttgat gaatgatgca aatggacttt
     7741 ctcagcctgc ggatgctgga ctagctcatc acgaaatgcg caactttctg gatttcgcga
     7801 gcagtaatgt agctgccagt cgacgtcgct gtgttgcagc tctgccatgt gcgacaggaa
     7861 aggggtgata ccaataccgc ccgcgataaa cagatgcttt ctggctgagg gaattagcgc
     7921 aaacaggtta ttaggcgttg aaatcgttaa ccgatcgccc acttttacct gctgatgcaa
     7981 aaagcgggaa ccgccgcgcg agttttcctc cagccgaacg gcaatctgat aacaagaggt
     8041 gtcatgcggc gaactcagta gtgaatacgc attgctgtac tggttatcac catcgctcat
     8101 ctgcacaatg acgtgacttc ctccggtaaa cgcaggtaat ggtttgccat cggttgccac
     8161 cagcgtgaag cgtttcacct gttcggtaag gggttcaacc tggctcacct gtacttcaaa
     8221 catttgatag tctgacattg ctgtactcca tcaaaaatca gcccagcggc ggaaaatacc
     8281 gccgccgatg tcattagtcc ttaaacacct gcgccagcag attatggaaa tgggcgatac
     8341 catgttcgga aatgccacta ccgctactgt cggccatgat gcgcccctga ccacgatagc
     8401 cacgcgattt cagccctttc tgtacgcttt caaccagacg taaatcttcc ggacggaaca
     8461 catcgcgata ccactcaatc agcgattttt gctcgtcggt taactcttca ttggtgaagt
     8521 aaatatcgta gttttgcagg gtagtttcag aatccaccgg gaattcataa atgaccgtca
     8581 tcatcccttt gatcggggtg acgttcagca tcgtgcacgg ccacagccag aaaccgtgga
     8641 atgccgcatc cgtaccctct tcaaatttaa acgactgttc ggacggtttg gcgaaaccgt
     8701 attgcagcgt ccagttaccg tgcatggtgt gccagtaacg atcaacctgt acggagtcgg
     8761 agaaacctgg atgcgccgga ccacagtgat agcactcgag atagttatcg acaatgttct
     8821 tccagttggc aggcgtgcgg gtggtaaagc gggccgccag tttcagatcg tggacttccg
     8881 ggcaggcttc cagcactttc gcgcccaggc cgggtaattg atcttctacg ctggtggcgt
     8941 tggggtccat gttgatgaag acgaatccgg catattcttc cagacgcacc ggaaccagtt
     9001 gcgctttgtc gctatcgaaa ttggcgacgt tttcgcagtt acgtgcatgg gccaggttgc
     9061 catcgagttt gaatgcccat gcgtgatacg ggcaggtaat cacatttttt gcttttcctt
     9121 caccgctcaa caactgatga ccacggtgcg gacacacgtt atagaacgcg cgcaaaacct
     9181 tatcacgacc gcgtaccagc acgatgcttt cgccaatgat ctcacgcgtc acataatcat
     9241 tggcattcgc cagttcgctg ctgtgagcga cgcaaatcca gcttttggcg aagacgttct
     9301 ctttttcgtg ttcaaacgcg ttctgatcgg tataaaaacg ggcaggaatg gtccacgcct
     9361 cttgcgggtt agcgcaaaaa ttttcgggta gtacaaagtc agggctcaga ttgctcatag
     9421 ggataccttt atcgttagga tgatggcgct cagttgtcgc ctttgaatac ggttcccgca
     9481 gggagcactg gcgttttttc cagggcttca accggtgtct gcgggagata atgttcaact
     9541 tgatgagccg gaatgtcggc gtaatcctgt ttcagccagc gaataaaccc gccgactttc
     9601 accagtaaaa tgacgaggaa gggaagggct gtgagcacga cggtggtttt catcgtttcc
     9661 agcgaagcac cggtaaacaa gatggaaagc gggatcagag tgatcaccac gcaccagaaa
     9721 agacgcagcc cacggtcagg atcgtcacct tcctggagat tacgcgtact ggtcgccgcc
     9781 atggtgtagg ccactgcatc catatgcgag gcaaggaaaa taatcatcac gcccaggtat
     9841 gcggcgagga acaatttacc ggctggcaac gacatcagaa cttgctgtac agctgtttcg
     9901 ccgcccagtg tttccagcac ctgtgggacg ttgattacgc cattgataaa ctgatgaatg
     9961 gcatagcttt ccattacgcc aaagaagaac cagcaaccga cggtgctgcc gaggatcagt
    10021 ccccagataa cttctttaat cttacgaccg cgggaaacgc gggtgacaaa cattgctacg
    10081 ccaggggtgt atgagatcca ccacagccag tagaaaacgg tccagttgcg ggtaaatgaa
    10141 ccatcgccaa gcggatcggt gaataagctc atttgcagga agttttgcgt ggtcaggccg
    10201 atggcattga tgatgctgtt ggtaataaat tcggttgggc cgacaatcag caccagtaat
    10261 ggcagcagga acgcgcccca gccaaccatt ttgctcagac gttgcaaacc gttgttgata
    10321 ccaatccacg agcttaggca aaaaatgccg ccggaaagca ggatcacaaa tgcctgcacg
    10381 gtgaagttat cgggtaaacc ggtcagcgcg gaaagcccac gggtaaaggt tgctgcggta
    10441 acaacaaggg aaatggtcag tgcgccgaca gtggcgatca ggaacatcaa atcgaccagt
    10501 tttccccatg ggccttgcgg gcgaacgccg gtaatagcag caataatgcc ggaaaggctc
    10561 agacctttgt ttttccgcac atgaaagtga taagccatga ttaatgaggc cagcgtataa
    10621 gttgcccagg cgctgatgcc ccagtggaag aaagagtagg gaacgctaaa ttcgagtgcc
    10681 tgttgtgaac gcggtgcgat atttaatcca ggtgtttgat aataataggc ccattcagca
    10741 accccccaat aaagcgtaga agaacctaaa ccggcacaaa taaacataaa cagccaggag
    10801 agcgtgctgt attccggttt tccttcgcca agacgaatat tgccgtattt actggtggct
    10861 aaataaatca ccagtcccat tgccagcaaa accaatacct gtacggcgga acctaacgta
    10921 cgcgtaacaa aatttgcatg ttacataaat taaacaatta agaatacgga aagccataaa
    10981 acacgaaacg gaaacaataa aaggtgaaat gacgcaggtt atttactgca aagaacgaat
    11041 aaaaaaaccg cgtcagtgac gcggttcaaa taaactggtt tgaccttaac gcaaaataat
    11101 tttgcaaatc gcgtcggcaa cctgtggcgt ggtggcattg cctttcatat caggtgtttt
    11161 cggcccgtga gcaatcactt cttcaattgc tgccagaata ccgttatgcg cttgctggaa
    11221 acgctcatcg ccattgccga gaaaatcgag catcattgcc ccggcccaaa tcgtggcgat
    11281 agggttagca atatttttcc cgtagatatc cggcgcggaa ccgtggacag gctcgaagag
    11341 cgacgggaaa gtgcgttccg gattcaggtt ggcggatgga gcaatgccaa tggtgccggt
    11401 gcaggccggg ccaagatcgg aaaggatatc gccaaacaaa ttggacgcca ccaccacatc
    11461 gaatcgttcc ggctgcatca caaaacgcgc gcagagaata tcaatatgct gcttgtccca
    11521 gcggatctcc gggtaattct cggccattgc ttccactcgc tcatcccagt acggcatgct
    11581 gatggctaaa ccgttcgatt tagtggcaga agttagtgtc ttacgtggac ggctttgcgc
    11641 aagttcgaag gcataacgca aaatgcgatc gacaccacgg cgggtaaata ccgattcctg
    11701 aatgacgact tcatgctctg taccttcatt cactctaccg ccgagcgagg aatattcgcc
    11761 ttcggtgttt tccctgacca cgtaaaaatc gatgtcgcca ggctgttttc ccgccagcgg
    11821 gcagggaacg ccaggaaaga gacgaaccgg gcgcaggttg acgtactggt cgaattcacg
    11881 acgaaatttc agcagcgaac cccacaacga aatatggtcc ggaacggtat ccggccagcc
    11941 gacggcacca aaatagatgg cgtcgaaacg gctaagttgc tcatgccagt cgtccggcat
    12001 cattttaccg tgatggctgt aatactcgca gctcgcccac tccatttgct caaaactcaa
    12061 ggcgaagccc cagcgctcag cggcagcctg taacacgcga atcccttcag gaaggacttc
    12121 tttgccaatc ccgtctcccg ggatcgcagc aatacgcatc gttttcatca ttgggttctc
    12181 acttcctgac catcaaaatt gacaacatca ccatcctata attgactgaa aaggaattaa
    12241 tccccgtaac tggtgaaaca taaaacacga atcatgaata atttaccgct gctgaatgat
    12301 ttgcgcgtct ttatgctggt ggctcgccgg gctggttttg ccgccgtggc ggaagaactg
    12361 ggcgtttcac cggcgttcgt cagcaagcgc atcgccttgc tggagcaaac gctaaacgtg
    12421 gtgttgttac accgcaccac ccgccgcgtc accattaccg aagaaggaga gcggatttat
    12481 gaatgggcgc agcggatttt gcaggatgtc ggtcagatga tggacgaact ttctgacgtg
    12541 cgtcaggtgc cgcaggggat gctgcgtatt atcagcagct ttggttttgg acgacaggtg
    12601 gtggctccgg cgttatcagc gctggcgaag gcgtatccgc aactggaatt acgttttgat
    12661 gtggaagacc gactggtcga tttggtcaat gaaggtgtcg atctcgatat tcgcattggc
    12721 gatgacatcg cccctaattt aatcgcccgc aaactggcga ccaattaccg tattctctgc
    12781 gcgtcgccgg aatttattgc gcaacatggc gcgccgaaac atttaaccga tctttctgca
    12841 ttgccgtgcc tggtcattaa agagcgcgat catccttttg gtgtctggca attacgcaat
    12901 aaagaaggcc cccatgcgat taaagtcacc ggcctactgt cgtctaatca tggagaaatt
    12961 gtccatcagt ggtgtctcga tgggcagggg attgctctgc gttcctggtg ggatgttagc
    13021 gaaaacattg ccagtggtca tttagtgcaa gtgctaccgg aatattacca gccagcgaac
    13081 gtctgggccg tttatgtttc aaggctggcg acgtcagcga aagtgcggat aacggtagaa
    13141 tttttacgcc agtattttgc cgagcactac ccgaattttt cactggagca tgcctgatta
    13201 atgattcaat tatcgggttg atatcaggtt aaaacctgat tttctccttt ctaagccgct
    13261 acagattggt tagcatattc acctttaatc gcgcatgatc gaaagataat taaagaggtt
    13321 aatgtgttcg ctgaatacgg ggttctgaat tactggacct atctggttgg ggccattttt
    13381 attgtgttgg tgccagggcc aaataccctg tttgtactca aaaatagcgt cagtagcggt
    13441 atgaaaggcg gttatcttgc ggcctgcggt gtatttattg gcgatgcggt attgatgttt
    13501 ctggcatggg ctggagtggc gacattaatt aagaccaccc cgatattatt caacattgta
    13561 cgttatcttg gtgcgtttta tttgctctat ctggggagta aaattcttta cgcgaccctg
    13621 aagggtaaaa atagcgaggc caaatccgat gagccccaat acggtgctat ttttaaacgc
    13681 gcgttaattt tgagcctgac taatccgaaa gccattttgt tctatgtgtc gtttttcgta
    13741 cagtttatcg atgttaatgc cccacatacg ggaatttcat tctttattct ggcggcgacg
    13801 ctggaactgg tgagtttctg ctatttgagc ttcctgatta tatctggtgc ttttgtcacg
    13861 cagtacatac gtaccaaaaa gaaactggct aaagttggca actcactgat tggtttgatg
    13921 ttcgtgggtt tcgctgcccg actggcgacg ctgcaatcct gatgctttca gcccgcgttg
    13981 tcgcgggctt cccatctata atcctccctg attcttcgct gatatggtgc taaaaagtaa
    14041 ccaataaatg gtatttaaaa tgcaaattat caggcgtacc ctgaaacggc tggaataaac
    14101 cgttttcagc gcattcaccg aaggagggaa aaggatgctt caaatcccac agaattatat
    14161 tcatacgcgc tcaacgcctt tctggaataa acaaactgca cctgccggaa tattcgaacg
    14221 tcatcttgat aaaggaacgc gcccgggggt ttacccacgc ctttccgtta tgcatggggc
    14281 ggtcaaatat ctcggctacg ctgatgaaca cagtgcagag cctgatcagg tgatccttat
    14341 cgaagcgggg cagtttgcgg tgttccctcc agaaaagtgg cacaacattg aagccatgac
    14401 tgacgatact tatttcaaca ttgacttctt cgtggctcct gaagtcctga tggaaggtgc
    14461 gcaacaacgg aaagtcattc ataacgggaa atgaatcatg ggcaaagcaa cgtataccgt
    14521 gaccgtcacc aataacagca atggcgtttc tgtcgattat gaaacagaga cgccgatgac
    14581 tttgctggtg ccagaagtgg cggctgaagt gataaaagat ctggtgaata ccgtacgttc
    14641 ttatgacacg gaaaacgaac atgatgtttg tggttggtaa ttatcactga tcgttgatgg
    14701 cgcaatttct gcgccatcgc aaaaaaaacc tccgtgatgc tcgtcacaaa tcttgccctc
    14761 ccgatgttgt gctatgcttt ttatcagcga ctaacccgct aatgcaaaac agataagtga
    14821 ggaaacaatg ggcattctgt catggattat ttttgggctt attgccggta ttctggcgaa
    14881 gtggatcatg ccaggtaaag atggaggtgg attctttatg actatcctgc tggggatagt
    14941 cggtgccgta gtcggcggat ggatcagcac gctgtttggc tttggtaaag tcgatggctt
    15001 caattttggc agcttcgtgg ttgccgttat tggtgcgatt gtcgtgctat ttatctacag
    15061 gaagattaaa agttaacgct taaattgcac aaaggctgca cacaggcagc ctttgctatt
    15121 ttttagaggt gacgttacca ccatcccagc tcagtgccga gtacgacaat aatcgccaca
    15181 cccatcataa taatcgttgt ttttttcatc tttatgctcc cggggcagca tagccgccaa
    15241 taaaaaacca tgctaaaaat acgaccgctg taatgaagat tacaaccgga aaaataatac
    15301 cgattcgcat gttatcacca atcaaaagga tgtgaatacg cctcaggaat gtagcgctgg
    15361 atgcgcgaca aaaggtgttt tctgtttgtg ttttttctcc tgatacatcg caatatcggc
    15421 agcatgcagg gcactgtctg catcggttgt ttcaggatcg acttctacta tgccaagact
    15481 ggcaccggga taatacaaat caacatcacc taagtgatat tctccacgta tttgctgctg
    15541 aatgcgttct cgcagcgacg aaatatccgc attctcgttg tttagtgaaa caactaaaaa
    15601 ctcatcaccg ccgagacgac caataacttc gccattttgc tggagcgtat taaggcgctc
    15661 gccaacctga atgagaaaca gatcgccact attatgacca aaacgatcat tgattaattt
    15721 gaagttatcc agatcgataa acgcgatcat tatcttatgg ttaagatgcc gggcgaggga
    15781 aaacagtgtc gtcagatttt caaaaatcgc ccgccgattc ggtagcccgg ttaacgagtc
    15841 ggtatacgat tgcgcaatca gcgcagcatt ggcttcgcgc agctgttcaa ccagtgcctc
    15901 tttttgaata tattgtgcaa tcagtccggc gaataactgt aaaacctgtt ccgcgcgttc
    15961 actccactgg cgcttctcac tgctggcggc gcaaagcgtg ccatagaatg atccatccgg
    16021 taagtgaatt ggcgtgctca gaaatgtggt gatgccaaga ttgcgtgccg caatacagtc
    16081 accccaacgg tcggggactt catcgctgaa aaagcagttt tcatcaatgg cgcgtttgca
    16141 taacgagtaa tcccacgaga cggtaaaatt ctccgggatg tacattttct ggctgttacg
    16201 ggcaaacata atatgctgca ggcgcgcttc gacatccact ttggtcaggt aggttgattc
    16261 catatcagtg accatttcca gcatctccag aagctgtcgg accagacttt ccagtgactg
    16321 ttctttggca agggattgcg agacgcgggc gataatctga tctgacacgg aacaactcca
    16381 ggatacggcg ggtaaatgct gattatttaa tctttgcagg catgataaaa catcatcaac
    16441 aaagatgaaa caagacgtaa tatgttttga gtgaatgtaa taaaaatagt gctgcaaaac
    16501 aaaacgatac cgcgatactc taatcttgga taaatatgtg agatcaataa atgaaaatta
    16561 tcagttttgt tctgccttgc ttgctggtcc tggctggttg ttcaacccct tctcagccag
    16621 aagcacctaa accgccgcag attggtatgg caaatccggc gtcggtctat tgccagcaga
    16681 agggcgggac gctcattcca gtgcagacag cgcaaggggt cagcaacaat tgcaaattac
    16741 cgggcggtga aacgattgat gaatgggcat tgtggcggcg tgaccatccg gctggtgaaa
    16801 aataaccgcc ggatgctgta ctaaaatcac aagctacgta gccagtcggc cagcaccagc
    16861 gcatggttct gcgtggtgtt ttttgctgag tagagcaggg tcagcggctg ttttttggcg
    16921 atgtccgcca gccgctttcc ttcttgctcg tgttgcgcca gttctgcaag atattgctcg
    16981 cgaaaggttg cataatcgac gacttcgccg tgaaaggctt tgcgcagttc cgttgacggc
    17041 gtgatttctt tatcccactc atcaagggct aaatcggttt ttttgatacc gcgcggccag
    17101 aggcggtcga ccagtatgcg ataaccatcg ctctgttcag ccggatcata aacgcgtttg
    17161 cactgaatat tcatcgtgtt tgttctccct ttcacgcatg atttgttacg tcactatagc
    17221 accggatatt agcgaatttc tttgtctctc ccggcgcaaa gtccgaaaat cgccatcagt
    17281 agtgaaagta tggcaacacc cataagtggt acagaccagt taccgttagc atcgtgtatt
    17341 ttacccatca gcggcggccc acaggctgcc aacaaatacc cgacggattg tgccatcccc
    17401 gagagtgccg ccgcctgatg cgcagaacta gcccgcagac caatgaacgt caaccccagt
    17461 atcattgttg cgccggaacc aaaaccgaaa agcagagtcc aggtgatcgc gtgcgctggc
    17521 ataaagcaga gcccaaccgc gcccactgcg cacatcaagg caacgaacgc tgcaatacca
    17581 cgctgatctt tcacatgatg taagaaaagt gggatcagca aaccgggtgc tgctgtggct
    17641 agttgcagca aaccatgcag tgaacccgcc tgtgcttcgc tatagccgtg actgatgagg
    17701 atcgccggaa gccagccaat aatcacgtaa tagaccagtg agttgatccc aagaaacaat
    17761 gtgacctgcc aggcaagcgg cgaacgccag ataccccgag tatgtaaggc gcgcgaggta
    17821 ctcaaatttg catgttgttg acttcgccac tgtggcagcc ataaaaaaag agccagcaga
    17881 ggaaaacaca tcagcatgag caacgcgcct tgccagccaa aaccgttcaa agccagcggc
    17941 acgaccatag ccgatcccag tgccgctgca gctcccattg tcagggaata tgcgccggta
    18001 agtctggcga cggaatgagg gaaatcgcgt ttaattaatc ctggcagtaa gacattgcct
    18061 aatgcaatcc caccgccaat gaccgctgta ccgccaaata ataagtaagg cgaagggaga
    18121 gagcgaattg cgataccagc acagatcaaa agtaacgcgg caaacaggct acgttccata
    18181 ccaaaacgtc gcgctactgg ggcagccaaa ggtgagatta gcgcaaaggc caataatggc
    18241 agggtggtca ataagccggt ttgcgctgtc gtcagcgagt aagcggaacg aatcgtatcc
    18301 agtaacggtg ctgcgccggt aaaggtgacg cgtaatgttg tggcaatcat cagaatgcca
    18361 gcgataagga caatcctgtt tttgccgctt aatgaagttg aacaggtcat atgcttctca
    18421 ttgttacaaa cgaggctgta ccttaccgtt tttattgtta tgttgaatca agctaaaatg
    18481 acaaattatc gctaagttcg gacaaaatga tgcacaggtt gaatctcaat ggctatgaac
    18541 ccgaccgaca ccatgaagcc gcggtcgcat tttgtattca cgccggaacg gatgagttaa
    18601 ccagtcctgt acatcagcac cgcaaaggac agctgatact ggcgctacat ggtgcaatta
    18661 cctgtacggt ggaaaatgct ttgtggatgg tgccgccaca atatgcggtt tggataccgg
    18721 gcggggtgga acatagcaat caagtaacag ctaatgctga actctgtttt ctgtttatcg
    18781 aacccagcgc agtgacaatg ccgacaacat gttgcacatt gaaaatatcg cccttatgcc
    18841 gggaattaat tttaaccctg gcaaacagga cgacgactca gcgtgctgag ccaatgaccc
    18901 gcagattaat tcaggtcctg tttgatgaac tccctcagca gccacaacaa cagctgcacc
    18961 tgcccgtttc ttctcatcct aaaatccgca cgatggtgga gatgatggcg aaagggcctg
    19021 tcgagtgggg ggcattgggg caatgggctg gcttttttgc gatgagtgaa cgcaatcttg
    19081 cccgactgat agtaaaagag acggggttga gttttcgcca gtggcgtcag cagttacagc
    19141 tgattatggc gcttcaggga ttagtgaaag gcgatactgt acagaaagtt gctcatacgc
    19201 tggggtatga ttcaacaacg gcctttatta ctatgtttaa gaaaggcctg gggcaaacgc
    19261 caggccgata tattgcgaga ttaactactg tttccccaca atcagcgaaa ccagacccgc
    19321 ggcaataagc ggcccaaccg gtacgccgcg aaacagcgct acgcctaaaa cagtgcctac
    19381 cagcagcccg gcgaccagtt gcggctggct gcccattaac gtcacgccgc gcccacccag
    19441 ccaggagaca atcacgccta ctgcaatcgc caccagtgat ttccagttca gaaacgagtg
    19501 aatcaaggtt gagggcggta gcgtcccgct ggcgatgggg gccataacgc caatcgtcag
    19561 aatgattatc ccgatactta gcccctgttt ttcaatccac ggaaaaaagg tgcttaacgg
    19621 tgtgacgcgg acaatgatta acaccagaat tgaaacggcg acagtggtgt tatgactgat
    19681 aaagcccagc gcagctaacc cgagcaggat cagcaaagtg acatcaaaca tcgtggtttc
    19741 cttgccaaaa aataataagc ctgcttactt tacgcttgct gcaggaagga agtagaaaat
    19801 ctttacgttt tttgcataaa aaatcaggcg aactgtcatc aaactgccat ttgtgcacgc
    19861 taacaataac gtgaaaacag ctatctcccg ggggcatgct atgaacgatc aaatgtttgt
    19921 cgagacactg attatcacgt catcgttttt tgccattgct gttgtactgg ttttgtccgt
    19981 tcttcttatc gaacggaccg gctagttacg cagtgcggcg gaaattgacc agttctggtt
    20041 gcgcaatgcg caaataatcc gcggttttca aaataacgga tttatccagc atgcctgcat
    20101 tgaaggcgat ttcatcaaat cgttcgaaga gtagagggtc ggcaaccagt ttgagttttg
    20161 gatggaagct gaaagggggg atcgcgccga agacacagcc tgtgagttca tcgacttccg
    20221 ccgggctggc caacgaagcg cgtaatccgc ctatatggct ggcgagttgg ctcagatcgg
    20281 cctgttgatc ggctgcgagg atcgccagaa catgttgatt tacgccattg cctttgactt
    20341 tacataccag tgccttagca ccctggccta gagcggtgcc acgaatttct gacaccgctt
    20401 cacatttacc taccgcttca tgggtaacga cgcggaagtc agcaccttct tgtgataata
    20461 aagcgattaa ccgctgatgc gtcacgcttc ctttagccat ttcagtcatt tcacgctcct
    20521 gagattacaa gcaaacaacc acagaaggtt atcatgaacg gctgtttttg ttctgcttat
    20581 tgacatataa acgctcatcg gaagctttat acgcatcatg taacgtatcg ttttctttca
    20641 tcgcgtaaat accggaagag aagccgatct ctttctgcgg cgcgatatgt tgcagacgtt
    20701 tttcgatacg ttcaggcagt tgtgctgcaa tttgcggcgt cgaatcgaca agaatgatgc
    20761 agaattcatc gccaccgagt cggatggcat aatcactttt acgaatcgac tgtttaatcg
    20821 cctgagctaa taacgtaatc gctaaatccc cctcctgatg accgagggtg tcatttattt
    20881 gctttaactt gtccatgtca atagcaataa acatcaccga agaaccggat tgcaccagtt
    20941 tctgcaaccg ctgctccagt tcaggggtta aaattttgcg attatacagt ccagtcatcg
    21001 catcactaat attttctcgc gacacatttt ggtataaacg gaagtgcatc cgcaccatat
    21061 tcagcaaaat taacgccgtc aaaatccaga acagaacgct tttccacgaa gacgtgataa
    21121 agtaaagaat atcaatggat aacgagacac gaatgccgcc cggtaagtca tggacgtaac
    21181 tgacatactg gaacagatta tcttcgctct ggttgatgat aatgtcgcgc cccgaatcgg
    21241 tatcggttag cgtgacattg agaaaacgcc agaggagagg gcggtcatga gtataaaaga
    21301 tattccgcag attgtttttg ttaatatcca gcagcacaat cccttttagc tgccctgcga
    21361 catataccgg cgtcagcaaa ctcatcacgt tctgtttagt acgctgatcc tggtaaatgc
    21421 tcgacaatac ggtacgcccg gtaaatacct tttcaatatc tttgcgatcg atgccaatac
    21481 ttcctgactg caggaaggac cagttattca tcgcaaagta ttcaacatta accggctcat
    21541 aaaaatagac atagcggtca ttgagatcga gataatagtg aaatttctct tcggccatcc
    21601 caagacctga accgtaatca tcctggtggc ggttgccttc cactgcctga tcaaaagcgg
    21661 gtaatagtgc tgcagcttcc acaattgtgt cgcagtcagt ggatgcggtt tgtagtgtgc
    21721 cgcgtaagcc cgggtattta tgggcagtca ggtttaagcc atgggtgtta ttggcagact
    21781 caaaagcctc gcagatggcg cgccgctgtt ctggcgacac ttccgactgc tcagcagcga
    21841 gagcgcgcat cacatgcgcg gcaatactct gattctgata cttatcataa agaaaggagg
    21901 agtctgcttt ctgcacgata tagcgcagat aggcactcat tgctctgtcg ctggcgacaa
    21961 gttcaaaaat aaggaaggaa gatgtcagca caatgacact tgcggcgata aaatgccgga
    22021 gcattctatg gtgcaatttc atgataaatg gcactccttc ggttagtgaa acgagaaaac
    22081 cagataaagt tcgattgcgg cctggcacag gggcgctaat tatactcatc tctgcgccgc
    22141 tggggagggg aaatttaggg gtaatagtaa taaattgtat gcaaaagcca cgcaaaaagc
    22201 atggctctga atatttttgc acttaaatat gatgaataat cactttgttg cccccctcgc
    22261 ttttcgcttc gcgtaaggct ttatctgctt ccgtcatgac aagcgagata ttacgcgtgt
    22321 cacccgttga aaaaaccgtg ccaatactga tggtcatttg ttcaggaaca tcatatctgt
    22381 tactaaagcc ggtcaggagt tcgacatttt tacgcatacg ttccgcaatg atttttgcct
    22441 gggcactatt gagttcggta aatagcaagc caaacacctc accctccagt cgcgctaaaa
    22501 tatcatcggg gcggatgctt tgctggataa tatcgacaat tgaaaccagc actttatcac
    22561 ccacacgatg tccccattgg gcattgatgc gtttgaactg attaatatca accagcatga
    22621 cacagaagtc cttaacaaca ggtcgcgaca ataatgactc tacgctgttg aaaaagtagc
    22681 gccgattata aatattggtc agcacatcat gaactgccag tttgctggag agttgcagct
    22741 cctgaaaaat gttataaatc agaaaagaca caacaaacag tttactggaa acttcaatcc
    22801 cgcgactgat ataccagata gtataattat actcatccag agtcagtaga agtaagttgc
    22861 agcatagcga tgccagacat aataatgcta ttaacggcca tagttcgctg gctaatcgtg
    22921 tgcgcatgat aataaagaac agtaaaaatg cccacagaca aaccaatatt tttgtatagt
    22981 tgattcccca ggtcgcagta tggttgtccg gacagtaatc gacgacatac aaagaatagt
    23041 cagcgttata actgctcaga ttgtgtgcca gaaggggaaa aactaaaaaa gggatcagcg
    23101 ccagcaacag gattcccgtt tttttcttat tgttgtcaag gatgttgtct tttccataac
    23161 aaaagagcgc cagcgaggtt aaacaaataa aactgagttg gcggaaaata tagaaaatag
    23221 aaacatcatt cgactttgtc tggatcagtg tactgccgtt aattggttta tggataatta
    23281 caatggtttc aactaaatag ataaggccac ttaaaaatgc aaggcttaaa atgagtgttg
    23341 gtaaaatttg tttgttagtg aaatatttca ttaacatgaa aagaaaaatg acggcgttaa
    23401 ggaaaaacaa agccacaaca accatcaggt aattcatctg tgggatgagt tttacatttg
    23461 tgttttcgtt atataaggta gtaatgcaaa ataaaattaa cgtcagcaat aaactgaaaa
    23521 taaaaaagct ttgagctttt aatttttgtg tacccataga aaccataaaa aggagagcaa
    23581 tgtgagt
//
LOCUS       DAPHKZ010000068        23343 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.068, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000068 DAPHKZ010000000
VERSION     DAPHKZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23343
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.068"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(531..1622)
                     /gene="ychF"
                     /locus_tag="RH288_002784"
     CDS             complement(531..1622)
                     /gene="ychF"
                     /locus_tag="RH288_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDV4031825.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAVLEKCLPQLENAGMLRALDLSAEEKAAIRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDVMNFLFNV"
     gene            complement(1739..2323)
                     /gene="pth"
                     /locus_tag="RH288_002785"
     CDS             complement(1739..2323)
                     /gene="pth"
                     /locus_tag="RH288_002785"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDV4031826.1"
                     /translation="MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAK
                     FFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGV
                     AKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ"
     gene            2601..2879
                     /gene="ychH"
                     /locus_tag="RH288_002786"
     CDS             2601..2879
                     /gene="ychH"
                     /locus_tag="RH288_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HDV4031827.1"
                     /translation="MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAH
                     GAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS"
     gene            complement(2934..4613)
                     /gene="dauA"
                     /locus_tag="RH288_002787"
     CDS             complement(2934..4613)
                     /gene="dauA"
                     /locus_tag="RH288_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HDV4031828.1"
                     /translation="MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIR
                     TLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATA
                     AIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL"
     gene            complement(4738..5685)
                     /gene="prs"
                     /locus_tag="RH288_002788"
     CDS             complement(4738..5685)
                     /gene="prs"
                     /locus_tag="RH288_002788"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDV4031829.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(5836..6687)
                     /gene="ispE"
                     /locus_tag="RH288_002789"
     CDS             complement(5836..6687)
                     /gene="ispE"
                     /locus_tag="RH288_002789"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDV4031830.1"
                     /translation="MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIE
                     LRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKR
                     FREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGANLS
                     PLHRAML"
     gene            complement(6687..7310)
                     /gene="lolB"
                     /locus_tag="RH288_002790"
     CDS             complement(6687..7310)
                     /gene="lolB"
                     /locus_tag="RH288_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HDV4031831.1"
                     /translation="MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQ
                     DVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEI
                     TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK"
     gene            7524..8780
                     /gene="hemA"
                     /locus_tag="RH288_002791"
     CDS             7524..8780
                     /gene="hemA"
                     /locus_tag="RH288_002791"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HDV4031832.1"
                     /translation="MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQILADEVGAEVIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMA
                     WLRAQSASETIREYRSQAEQVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAP
                     TKSLQQAARDGDNERLNILRDSLGLE"
     gene            8822..9904
                     /gene="prfA"
                     /locus_tag="RH288_002792"
     CDS             8822..9904
                     /gene="prfA"
                     /locus_tag="RH288_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDV4031833.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQ
                     LSDVSRCFTEWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVME
                     GKLDMLIEPIIQEHQADQLAALSEQE"
     gene            9904..10737
                     /gene="prmC"
                     /locus_tag="RH288_002793"
     CDS             9904..10737
                     /gene="prmC"
                     /locus_tag="RH288_002793"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDV4031834.1"
                     /translation="MEYQHWLREAISQLQASESPRRDAEILLEHVTGRGRTFILAFGE
                     MQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPEQPCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKN
                     IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIV
                     HIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFILAGYHDVETCRDYGDNERVTLGRYY
                     Q"
     gene            10734..11126
                     /locus_tag="RH288_002794"
     CDS             10734..11126
                     /locus_tag="RH288_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HDV4031835.1"
                     /translation="MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIV
                     PPVVDTLLLLSGIALMAKAHILPFSGQAQWLTEKLFGVIIYIILGFIALDYRRMHSQQ
                     ARIIAFPLALVVLYIIIKLATTKVPLLG"
     gene            11130..11939
                     /locus_tag="RH288_002795"
     CDS             11130..11939
                     /locus_tag="RH288_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HDV4031836.1"
                     /translation="MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSL
                     AKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLG
                     AVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNI
                     SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEI
                     RDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRAQINNIAHKHIVLH"
     gene            11975..12829
                     /gene="kdsA"
                     /locus_tag="RH288_002796"
     CDS             11975..12829
                     /gene="kdsA"
                     /locus_tag="RH288_002796"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HDV4031837.1"
                     /translation="MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
                     EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     AQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKG
                     FEELDTSK"
     gene            complement(12978..13085)
                     /locus_tag="RH288_002797"
     CDS             complement(12978..13085)
                     /locus_tag="RH288_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic polypeptide LdrA/LdrC"
                     /protein_id="HDV4031838.1"
                     /translation="MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK"
     gene            complement(13513..13620)
                     /locus_tag="RH288_002798"
     CDS             complement(13513..13620)
                     /locus_tag="RH288_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic polypeptide LdrB"
                     /protein_id="HDV4031839.1"
                     /translation="MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK"
     gene            complement(14048..14155)
                     /locus_tag="RH288_002799"
     CDS             complement(14048..14155)
                     /locus_tag="RH288_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic polypeptide LdrA/LdrC"
                     /protein_id="HDV4031840.1"
                     /translation="MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK"
     gene            complement(14559..15659)
                     /gene="chaA"
                     /locus_tag="RH288_002800"
     CDS             complement(14559..15659)
                     /gene="chaA"
                     /locus_tag="RH288_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HDV4031841.1"
                     /translation="MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINL
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAH
                     SSLWHAIWLIIHLIAVIAVTKMNASSLETLLDSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFALGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAHLALFAAYLMTIFA"
     gene            15929..16159
                     /gene="chaB"
                     /locus_tag="RH288_002801"
     CDS             15929..16159
                     /gene="chaB"
                     /locus_tag="RH288_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HDV4031842.1"
                     /translation="MPYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKEDRRD
                     DASREETAHKVAWAAVKHEYAKGDDDKWHKKS"
     gene            16317..17012
                     /gene="chaC"
                     /locus_tag="RH288_002802"
     CDS             16317..17012
                     /gene="chaC"
                     /locus_tag="RH288_002802"
                     /EC_number="4.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-specific
                     gamma-glutamylcyclotransferase"
                     /protein_id="HDV4031843.1"
                     /translation="MITRDFLMNADCKTAFGTIEESLLWSAEQRAASLAATLACRPDE
                     GPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGG
                     RTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGRTVNAIVFIMDPRHP
                     EYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLA
                     ENFPDGVLRPGFA"
     gene            complement(17056..17409)
                     /gene="ychN"
                     /locus_tag="RH288_002803"
     CDS             complement(17056..17409)
                     /gene="ychN"
                     /locus_tag="RH288_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/F sulfur relay family protein YchN"
                     /protein_id="HDV4031844.1"
                     /translation="MQKIVIVANGAPYGSESLFNSLRLAIALREQESNLDLRLFLMSD
                     AVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLIDGVEIGTLV
                     ELAQWTLSADKVLTF"
     gene            17594..18988
                     /gene="ychO"
                     /locus_tag="RH288_002804"
     CDS             17594..18988
                     /gene="ychO"
                     /locus_tag="RH288_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter invasin YchO"
                     /protein_id="HDV4031845.1"
                     /translation="MSRFVPRIIPFYLLLLVAGGTANAQSTFEQKAANPFDNNNDGLP
                     DLGMAPENHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHV
                     ESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDNGLVSNV
                     GVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQT
                     ATQEQRMARGYDLTARMRMPFYQHLNTSVSLEQYFGDRVDLFNSGTGYHNPVALSLGL
                     NYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVAESQSLRGSRY
                     DNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQ
                     ILSLTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVE
                     PFDALSNDELRWEP"
     gene            complement(18989..19639)
                     /gene="narL"
                     /locus_tag="RH288_002805"
     CDS             complement(18989..19639)
                     /gene="narL"
                     /locus_tag="RH288_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HDV4031846.1"
                     /translation="MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQG
                     IELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     gene            complement(19632..21428)
                     /gene="narX"
                     /locus_tag="RH288_002806"
     CDS             complement(19632..21428)
                     /gene="narX"
                     /locus_tag="RH288_002806"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HDV4031847.1"
                     /translation="MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGL
                     QDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
                     VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNN
                     MSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQ
                     NLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRL
                     ADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLT
                     TFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALS
                     NALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGD
                     CRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE"
     gene            21767..23158
                     /gene="narK"
                     /locus_tag="RH288_002807"
     CDS             21767..23158
                     /gene="narK"
                     /locus_tag="RH288_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HDV4031848.1"
                     /translation="MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGR
                     RWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWI
                     WVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGL
                     LFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKK"
BASE COUNT         5744 a         5833 c         5987 g         5779 t
ORIGIN      
        1 caattcgtta ctataaatat ggcaaaaata ttacaacaaa cagcggttaa aaaatttggt
       61 gaagattttt tgtaataatc ctaattagtt atgggaattt cgcttgatgt atctgcataa
      121 caaaaacaat atgcgccatt tttgcattac taataagaaa aagcaaaaaa catcgatatt
      181 catttttggt caatgggttt tctggcctat cgttgttatt gtgctactgg ttatcatttt
      241 catcttgcca gcatattgga gcgtgatcaa ttttgatcag ctgtgaaggg ggctgatgtg
      301 tagtgataca aaaacttacg ttatatcact gctaatgaga tatccgtcat ctgaacactt
      361 atgtctttaa ttattctcgt ggttcactat aggcaataag cacaaaagtg taggatgtta
      421 caagaatgat taggactcgg tgaaatgaaa aatccacgca attgcgtgga ttttatatac
      481 ttttgcgctc ttcatgagat ttagcgaaac ctcatgagac aataaattaa ttagacgttg
      541 aaaaggaagt tcatcacatc gccatctttc acgatgtaat ctttaccttc tgcacgcatt
      601 ttgcctgctt ctttcgcgcc ttgttcacct ttgtaagtga tgaaatcttc aaacgagatg
      661 gtttgtgcac ggataaagcc tttttcaaaa tcagtatgga ttttgcccgc tgcctgcggc
      721 gcggttgctc caaccggaat ggtccatgca cgcacttctt tcaccccagc ggtgaagtaa
      781 gtttgcaggt tcagcagttt ataaccggca cggatcacac ggttcaggcc cggctcttcc
      841 agcccaagct cctgcataaa ctcgtcacgt tcttcgtcgt ccagttcggc aatgtctgct
      901 tcaacagcag cacaaaccgg aaccacaaca gaaccttctt tcgccgcgat ttcacgcacc
      961 tggtcaagat atgggttgtt ttcaaaaccg tcttcgttga cgttggcgat gtacattgtt
     1021 ggtttcagcg tcaggaagct caggtaacga atagccgctt tctcttcagc gcttaaatcc
     1081 agcgcgcgca gcatacctgc attttccaac tggggcaggc atttttccag gaccgccagc
     1141 tcagctttcg cgtctttatc gccacctttg gctttcttct gtacgcgatg aatcgcacgt
     1201 tcgcaggtgt cgaggtctgc cagcgccagt tcggtgttga taacttcaat atcgtcagcc
     1261 gggttaactt tgccggaaac gtgaatgatg ttgtcatttt caaagcagcg aacaacgtga
     1321 ccgatcgctt cggtttcacg gatgttggtc aggaactggt tacccagacc ttcgcctttc
     1381 gatgcgcctt ttaccagacc ggcgatatcg acaaattcca tggtcgtggg aagcgtacgc
     1441 tgcggtttta cgatttcagc cagttgatcc aggcgaggat caggcattgg tacgacgcct
     1501 gtgttcggct caatggtgca gaatggaaag ttggccgctt caataccggc tttggtcagc
     1561 gcgttgaaca gggtagattt cccgacgttg ggcaaaccga cgataccgca tttgaatccc
     1621 atgatttaaa tcaccttaat atcttaataa tcaacctgtt attgctaaca gcttgcagaa
     1681 atggaaataa ctttgcctat tatacacggc actcggcaaa aatgccgcag acaacgactt
     1741 attgcgcttt aaaggcgtgc aatcggttcg ttgctttggt caagccatct gtaaaccaca
     1801 tttcagtaca acgcgccgct tcgtcaatgg cttcatcaat taacttctgt tcactaacag
     1861 gcggtttgcc taacacaaaa ccgacaactt tatttttatc gcccggatga ccgattccga
     1921 tgcgtaaacg gtgaaagtta gggttattac ccaatttact gatgatgtct ttcagtccat
     1981 tgtgaccacc atggccaccg cccaatttaa atttggcgac gccaggaggc agatccagtt
     2041 cgtcgtgggc caccagaatt tcgtccggat taatgcggaa aaaactggcc atcgccgcaa
     2101 cggctttgcc gctgagattc ataaatgtag tcgggactaa caggcggaca tcttcgcctc
     2161 caagagtgac tcgcgaagta taaccaaaga atttagcctc ttcgcgcagc ggagcgcgca
     2221 aacgctctgc cagtaagtca acgaaccagg caccagcatt atgtcgcgtt gcggcgtatt
     2281 cagcaccggg gttcgccagg ccgacaatca atttaatcgt cacgtttttt tgtcctgagt
     2341 gtgtacataa ctggcgcgta gtttactggt tgcggccccg cttgacaaaa aactgcgtat
     2401 caaatgcaga taacgtaata attgcctgag tggactatta gaaagtcaag gtgttcaggc
     2461 gtttatttgt aaagttttgt tgaaataagg gttgtaattg tgatcacgcc cgcacataac
     2521 ccactgggtg ttgtctatac tttacacata aggaagatgg gtattccctg ttacaaccca
     2581 gaaagttccg gaggtgacat atgaaacgca aaaacgcttc gttactcggt aacgtgctca
     2641 tggggttggg tctggtggta atggtggtcg gcgtggggta ttcaatcctc aaccagttac
     2701 cacagtttaa tatgccccag tatttcgcac atggtgcagt gctaagtatt ttcgtcggtg
     2761 ccattctctg gctggcgggt gcccgtgttg gcgggcatga acaggtgtgc gaccgttact
     2821 ggtgggttcg ccactatgac aaacgttgcc gccgtagcga taatcgccgt catagctaac
     2881 aaataatgca gtttgctgac cagtcagttt gcgctgactg gtcaatctcg tacttataaa
     2941 tccgccatcg ccgcgcgacg attcgggaag aacgccaggc gtcccgggat cggttgaatg
     3001 ccagcgcgag ccatagtgcg cagtggctgg aattccacgt tgcacacgcg cagttcacat
     3061 ccctcgggca gacgcttcac aaaacgctgg aacgcatcaa gaccaccagc atcaagtacc
     3121 ggaacggcat cccacttcag aatcacaatc cgtttgcctt caagacgtga ctccaggtcc
     3181 gtgaataagc cttcagcagc agcaaaaaac agcgggccaa taacgcgcag aaccaggaca
     3241 tcgtctggaa catctacgac taccggtgcc aggcgagtca tacgtgcgat acgacgcata
     3301 aacagcagcg atgccagcac gatccccacg ctgatggcaa taaccatatc aaacaacacg
     3361 gtcagcgaca tgcacagcag catgacgatg atgtcatctt tcggcgcatg acgcagcaag
     3421 tcgaccactt tgtgcgcttc actcatgttc cacgccacca tcaacagcag ggctgccatg
     3481 gcggaaagcg gcagccagga gagcagcggt gccagtacca gcagggcaag aataaccaga
     3541 atagagtgga tcaccgccga gataggggac gttgccccgg cacggacgtt agcggcagaa
     3601 cgcgcgatgg cagctgtagc ggtaatacca ccaaagaacg gagcgataat attccccagt
     3661 ccctgtccaa ccagttcgct gttcgccttg tgtttcgtcc cggtcatacc atccagcacc
     3721 acggcgcaga gcagagattc gattgcgccg agcattgcca ttgagaatgc cgcaggcagc
     3781 agtgtgcgaa tagaatccca ggttagcgtg aattctgaat taggcagatc ccacggcagc
     3841 accagttgcg gcagcagttg cggaataccg ttaccctgag aaccatcggc caggacgtag
     3901 tggaattgcg aaccgatggt agcaacatgt ccgccgagca ggttaacaat ccccatcacc
     3961 gcgcaaccag ccagcaaggc cggaaggtga ccgggtaaac gaatgcccag acgcggccaa
     4021 aaaacaagaa tacctagcgt cacaatgcca atggcagcat cacccacatt aatggtcggc
     4081 agcgccataa ataatgcgcc gactttttgt agataatgtt ccgggacatg ggccatttgc
     4141 agaccgagaa aatctttaat ctgcatggta ccgatggtga tcccgatacc cgaggtgaaa
     4201 cctaaggtga cggaaaccgg aatatactca atcaggcgac caaagcgtgc cagacccatc
     4261 agaatcaaaa agatccccga cagcaaggtc gcaaccagca gtcctgccag tccaaactgt
     4321 tgcgacacgg gatagagaat taccacaaat gccgcagtcg gaccggaaac gctaaagcgt
     4381 gacccacccg tcagagcaat gacaatcccc gcaacagctg cggtatataa accgtactgg
     4441 ggtgccacac cactaccaat agccaacgcc atcgccagcg ggatagcaat aatcccgacg
     4501 gttatcccgg caatcaggtc acgggtaaac cgtgcggcag tatatttttc tttccagcaa
     4561 gcgtcgatca gagcgcggaa aggcatcaca tgtgaggaaa atattttgtt cacaataatg
     4621 tttcatccgt gagcgcatca tctgtcaact aaatggcagg tgaaggaggc ataggtcata
     4681 caaatggata ttacagacaa aaaaacccgc cgcagcgggt ctttgagccg ggttcgatta
     4741 gtgttcgaac atggcagaga tcgattcttc gttgctgata cgacgaatcg cttcggccag
     4801 catacctgac agggtcagag tacgcacgtt cggcagtgat ttgatttcat cgctcagcgg
     4861 aatggtatcg cagacaacga cttcatcaat tacagagtta cgcaggttgt tcgccgcgtt
     4921 gccagagaag atcgggtgag tcgcgtacgc aaatacacgt ttagcaccac gttctttcag
     4981 agcttcagca gctttacaca gcgtaccgcc agtgtcgatc atatcatcga ccagtacgca
     5041 gtcacgacct gcaacgtcac cgatgatatg catcacctgt gaaacgttcg cacgcggacg
     5101 acgtttgtcg atgattgcca tatcggtatc gttcagcagc ttagcgatag cgcgggcacg
     5161 cacaacgccg ccgatgtccg gagaaaccac aattgggtta tccagattca gctgcagcat
     5221 gtcttccagc aggatcgggc taccaaatac gttatcaacc ggaacgtcga agaaaccctg
     5281 aatctgttca gcgtgcagat ccactgtcag cacacggtca acaccgacgc tggagaggaa
     5341 gtctgcaacc actttcgcag tgattggtac acgagcggaa cggacgcgac ggtcctggcg
     5401 cgcatagcca aagtagggga taacagcggt gatacgacct gcggaagcac gacgcagggc
     5461 atcaaccata acgactaatt ccatcaggtt gtcgttagta ggggcacaag tggactggat
     5521 gatgaaaata tcaccaccgc gtacattttc attaatttgt acgctgactt cgccatcgct
     5581 aaagcgacct acagcggcgt cgccgagtga agtgtacagg cggttggcaa tacgttgtgc
     5641 tagttccggg gtggcgttac cagcaaaaag cttcatatca ggcacgagaa gaacctcagg
     5701 catgcgtcca ttggtggaaa gaatctgccg aaaactgtgc gggccaggca tgatcctttc
     5761 caggcggtgt attaaagagc gcgatgcaac gtctggaaca aggtgacgtt gtcaccgaaa
     5821 ctcagcttgc ccggcttaaa gcatggctct gtgcaatggg gaaagattag cgcctttcgc
     5881 cacaaagcca ttgagccatt ccggggcttg ctctagcacc tggcgggctt cagactctgt
     5941 atcaaattca gcaaagacac aggcccctgt cccagtcagg cgcgacgggg cgtattctaa
     6001 cagccaggaa agcaccgcat caacctcgcg aaaacgtttt cttgcgataa cctcgcaatc
     6061 attgctgaat tcacatttta gcaacgtttc tattgacctt tttggcgtat tgcgcgggag
     6121 ttcaggatct ttaaaaatca ccggagtcgg aatacttaca ccagggtgcg ccaccagata
     6181 ccacttctct ggcggatcca ccggcgttag tatttcacca acgccttcgg caaacgcggc
     6241 atgcccccga acaaagacag gaacatctgc gcccagcgtc agccccattt ccgccagctc
     6301 atccatgctt agcccgcatt gccagagatg atttaatgcc accaggaccg tcgcggcatt
     6361 ggatgaacca ccgccgagac cgccgcccat cggcaaacgc ttgtcaatgc tgatattcgc
     6421 accgcttccc gtcggaagac gcccgctgtc tgccgcagtt ttcatcaaca atcgcgctgc
     6481 gcgaacgatc aggttatctt catgttccac gccttcaacg ggcgttaaca gacgaatatc
     6541 cccatcgtca cgaagctcaa tgctgatggt gtcgccgtaa tcaagaaact gaaacagcgt
     6601 ttgcagcgtg tggtaaccat ccgcacgctg accggtaatg tataaaaaca gattaagttt
     6661 tgccggagag ggccactgtg tccgcattat ttcactatcc agttatccat ttttaacttg
     6721 atgcgttgac caccgtcggt gagttccata ttggctggca tcgcaggttg cgttttggtg
     6781 tcataaccac cataaacaac cttccagttt ttgccattct ggctgtaggt aatttcgctc
     6841 aggcggtact ggtcgtccag tttgtagtcg gttgcatcac ccggtaaacc taaaatccac
     6901 tggcgcaagc tgttgagcgg aattggcatt ccggtcaatt tgccaatcat ctcttcggcg
     6961 tcatcggcgg tataacgctg acctttattg tcgactaact gcacgttacc cggttgagca
     7021 ttcagctcca gttccgtgct gcccaatggg ttagtgagca gcagacggta gcgatcctgg
     7081 ccggtttgct gccagaaaaa gcgggcgtac actttttgtt ggtcagaaat ataagcgaac
     7141 gcgccgcgag tctgatactg attaagattg cgcacgtctt gctgatgctg acgccattgt
     7201 ggcgaatccg ggcttttgcc aggacctttg ggcgtggtaa cggaacaggc agtgagcaca
     7261 agagcagcca gcggtagcag gcggataaga cgaaaatcgg gcaggggcat agtgatgaca
     7321 agtccttgag atacgttgca gttataaccc ttaatgctag cgttaccgtc cgctatcgtc
     7381 tatgttcaag ttgtcttaat tgccagaatc taacggcttt cggcaattac tccaaaaggg
     7441 ggcgctctct tttattgatc ttacgcatcc tgtatgatgc aagcagacta accctatcaa
     7501 cgttggtatt atttcccgca gacatgaccc ttttagcact cggtatcaac cataaaacgg
     7561 cacctgtatc gctgcgagaa cgtgtatcgt tttcgccgga taagctcgat caggcgcttg
     7621 acagcctgct tgcgcagccg atggtgcagg gcggcgtggt gctgtcgacg tgcaaccgca
     7681 cggaacttta tcttagcgtt gaagagcagg acaacctgca agaggcgtta atccgctggc
     7741 tttgcgatta tcacaatctt aatgaagaag atctgcgtaa aagcctctac tggcatcagg
     7801 ataacgacgc ggttagccat ttaatgcgtg ttgccagcgg cctggattca ctggttctgg
     7861 gggagccgca gatcctcggt caggttaaaa aagcgtttgc cgattcgcaa aaaggtcata
     7921 tgaaggccag cgaactggaa cgcatgttcc agaaatcttt ctctgtcgcg aaacgcgttc
     7981 gcactgaaac agatatcggt gccagcgctg tgtctgtcgc ttttgcggct tgtacgctgg
     8041 cgcggcagat ctttgaatcg ctctctacgg tcacagtgtt gctggtaggc gcgggcgaaa
     8101 ctatcgagct ggtggcgcgt catctgcgcg aacacaaagt acagaagatg attatcgcca
     8161 accgcactcg cgaacgtgcc caaattctgg cagatgaagt cggcgcggaa gtgattgccc
     8221 tgagtgatat cgacgaacgt ctgcgcgaag ccgatatcat catcagttcc accgccagcc
     8281 cgttaccgat tatcgggaaa ggcatggtgg agcgcgcatt aaaaagccgt cgcaaccaac
     8341 caatgctgtt ggtggatatt gccgttccgc gcgatgttga gccggaagtt ggcaaactgg
     8401 cgaatgctta tctttatagc gttgatgatc tgcaaagcat catttcgcac aacctggcgc
     8461 agcgtaaagc cgcagcggtt gaggcggaaa ctattgtcgc tcaggaaacc agcgaattta
     8521 tggcgtggct gcgagcacaa agcgccagcg aaaccattcg cgagtatcgc agccaggcag
     8581 agcaagttcg cgatgagtta accgccaaag cgttagcggc ccttgagcag ggcggcgacg
     8641 cgcaagccat tatgcaggat ctggcatgga aactgactaa ccgcttgatc catgcgccaa
     8701 cgaaatcact tcaacaggcc gcccgtgacg gggataacga acgcctgaat attctgcgcg
     8761 acagcctcgg gctggagtag cagtacatca ttttcttttt ttacagggtg catttacgcc
     8821 tatgaagcct tctatcgttg ccaaactgga agccctgcat gaacgccatg aagaagttca
     8881 ggcgttgctg ggtgacgcgc aaactatcgc cgaccaggaa cgttttcgcg cattatcacg
     8941 cgaatatgcg cagttaagtg atgtttcgcg ctgttttacc gaatggcaac aggttcagga
     9001 agatatcgaa accgcacaga tgatgctcga tgatcctgaa atgcgtgaga tggcgcagga
     9061 tgaactgcgc gaagctaaag aaaaaagcga gcaactggaa cagcaattac aggttctgtt
     9121 actgccaaaa gatcctgatg acgaacgtaa cgccttcctc gaagtccgag ccggaaccgg
     9181 cggcgacgaa gcggcgctgt tcgcgggcga tctgttccgt atgtacagcc gttatgccga
     9241 agcccgccgc tggcgggtag aaatcatgag cgccagcgag ggtgaacatg gtggttataa
     9301 agagatcatc gccaaaatta gcggtgatgg tgtgtatggt cgtctgaaat ttgaatccgg
     9361 cggtcatcgc gtgcaacgtg ttcctgctac ggaatcgcag ggtcgtattc atacttctgc
     9421 ttgtaccgtt gcggtaatgc cagaactgcc tgacgcagaa ctgccggaca tcaacccagc
     9481 agatttacgc attgatactt tccgctcgtc aggggcgggt ggtcagcacg ttaacaccac
     9541 cgattcggca attcgtatta ctcacttgcc gaccgggatt gttgttgaat gtcaggacga
     9601 acgttcacaa cataaaaaca aagctaaagc actttctgtt ctcggtgctc gcatccacgc
     9661 tgctgaaatg gcaaaacgcc aacaggccga agcgtctacc cgtcgtaacc tgctggggag
     9721 tggcgatcgc agcgaccgta accgtactta caacttcccg caggggcgcg ttaccgatca
     9781 ccgcatcaac ctgacgctct accgcctgga tgaagtgatg gaaggtaagc tggatatgct
     9841 gattgaaccg attatccagg aacatcaggc cgaccaactg gcggcgttgt ccgagcagga
     9901 ataatggaat atcaacactg gttacgtgaa gcaataagcc aacttcaggc gagcgaaagc
     9961 ccgcggcgtg atgctgaaat cctgctggag catgttaccg gcagagggcg tacttttatt
    10021 ctcgcctttg gtgaaatgca gctgactgac gaacaatgtc agcaacttga tgcgctactg
    10081 acacgtcgtc gcgatggtga acccattgct catttaaccg gggtgcgaga attctggtcg
    10141 ttgccgttat ttgtttcgcc agcgacctta attccgcgcc cggatacgga gtgtctggtg
    10201 gagcaggcac tggcgcggtt gcctgaacaa ccttgccgta ttctcgatct cgggacgggt
    10261 accggggcga ttgcgcttgc gctggctagc gagcgcccgg actgcgaaat tatcgctgta
    10321 gatcgtatgc ctgatgctgt ctccctggca caacgtaatg cccagcatct ggcgatcaaa
    10381 aatatccaca ttctgcaaag cgactggttt agcgcgctag ccgggcagca gtttgcgatg
    10441 attgtcagca atccgccgta tattgacgag caggaccctc atcttcaaca aggcgatgtc
    10501 cgctttgagc cgctcactgc gctggttgcg gcagacagtg gaatggcaga catcgtgcat
    10561 atcatcgaac agtcgcgtaa cgcgctggta tccggcggct ttctgcttct ggaacatggc
    10621 tggcagcagg gcgaagcggt gcgacaagca tttatcctcg cggggtatca tgacgtcgaa
    10681 acctgccgtg actatggtga taacgagcgc gtaacgctcg gccgctatta tcaatgacaa
    10741 gtttttctac actgcttagt gttcatctta ttagtatcgc gctttctgtt gggctattaa
    10801 ccttacgttt ctggctacgt tatcagaagc atccacaggc atttgctcgc tggacgcgca
    10861 ttgtgccgcc ggttgtcgat acgctgttac tgttaagcgg cattgcgttg atggctaaag
    10921 cgcacatcct gccattttcc gggcaggcac agtggctgac tgaaaagctg tttggagtta
    10981 tcatttatat cattttgggt tttattgcac tcgattatcg tcgtatgcac agtcagcagg
    11041 cgcgcattat tgccttcccg ctggcgttgg tggtgctgta catcatcatt aaactcgcca
    11101 ccacaaaagt accgttactg gggtaagtca tgagatcgtt agctgatttc gaatttaata
    11161 aagcgccatt gtgcgaaggc atgatcctgg cttgcgaagc aatccgccgc gattttccct
    11221 cgcaagatgt ttacgacgaa ctggagcgtc tcgttagtct ggcgaaggaa gaaatcagcc
    11281 agcttctgcc tttagaagag cagttggaaa aactgatcgc gctgttttac ggcgactggg
    11341 gatttaaagc ctcacgcggt gtttatcgtc tttccgatgc attatggctg gaccaggtgt
    11401 taaagaatcg acagggcagt gcggtatcat taggtgcggt tttattatgg gtcgcgaatc
    11461 gtctcgattt gccgctgctg ccggtgattt tccctacgca gctgatattg cgcattgaat
    11521 gtccggatgg cgaaatttgg ctgattaatc cttttaacgg tgaatcgtta agcgaacata
    11581 tgctggacgt atggttaaag ggaaatatca gcccgtcggc ggaactgttt tatgaagacc
    11641 ttgatgaagc tgataacatt gaggtaatcc gcaaattgct ggatacactc aaagcctcgt
    11701 tgatggaaga aaatcagatg gagctggcgt tacgcaccag cgaagcttta ttacaattca
    11761 accctgaaga tccctatgaa attcgcgatc gcgggttgat ttatgcgcaa ctggattgcg
    11821 aacacgttgc gttgaacgat ttaagttatt tcgttgaaca gtgtccggaa gacccgatca
    11881 gcgaaatgat ccgtgcgcaa ataaataaca tcgcgcataa acatattgtg ctgcattaat
    11941 taatcgacat tttactcaag attaaggcga tcctatgaaa caaaaagtgg ttagcattgg
    12001 cgacatcaac gtagcaaatg acctgccgtt cgtactgttt ggcggtatga acgtgttgga
    12061 atctcgcgat ctggcgatgc gcatttgcga gcactacgta actgtgaccc agaaactggg
    12121 tatcccttac gtgttcaaag cctcttttga caaagccaac cgctcctcca tccactctta
    12181 tcgtggaccg ggcctggaag aagggatgaa aatcttccag gagttgaagc agacttttgg
    12241 cgtgaaaatt atcaccgacg ttcacgaacc aagtcaggca cagcccgttg ctgatgtcgt
    12301 ggatgtgatt cagttgccgg cgtttcttgc tcgccagact gacctggttg aagccatggc
    12361 gaaaaccggt gcggtaatta acgtcaagaa accacagttt gtcagcccgg gacagatggg
    12421 taatatcgtt gataaattca aagaaggcgg caacgaaaaa gtgattcttt gcgatcgcgg
    12481 tgctaacttc ggctatgaca acctggttgt cgatatgctg ggcttcagca ttatgaagaa
    12541 agtgtctggt aactcgccgg tgattttcga cgtgacccac gcactgcaat gccgcgatcc
    12601 gtttggcgca gcttccggtg gtcgtcgtgc tcaggtggct gagctggcac gagccggtat
    12661 ggcggtaggt ctggcggggc tgtttattga agcgcatccg gatccggaac atgcgaaatg
    12721 tgatggtcca tccgcgctgc cgctggctaa actggaaccg ttcctcaagc agatgaaagc
    12781 gattgatgat ctggtgaaag gtttcgaaga actggatacc agcaagtaat cttttttgct
    12841 tgaaaaataa agtattagcg ttctgcgtta agactttttt catgggtgcc ggatacaaaa
    12901 aaggccgcag gctgttaccc ctgcggccgg tttcgggcgc atattgccat cacggcagcc
    12961 tgacgcccgt tttcacctta cttccggtta cgccaccagc tgacaatcgc tgcggtaata
    13021 attcccgcca ggatcggtgc tgccaggtcg tgccagaaaa tcatggcaaa ctgcgcgagc
    13081 gtcatatagc cgccttgttg taatgacaac attttgcggc tattcttgaa ttgttctggt
    13141 tcaagattag cccccgttct gttgtcaggt tgtacctctc aacgtgcggg ggttttctct
    13201 ttccagcaac caatgccacc agggataaag cccccgcaac attgcgcctc accggataac
    13261 gccggcttgg tgtggatact acgactcaat tcatcttcac ttcatccctg aaatgtttgc
    13321 aatgaagagt gcattccggt ttttcaacag ctgttacagt catttcatga gtgctctgga
    13381 tgaggcttcc agctcgggtt gccaatattt acttgtggaa gtgataaaga caaaaatggc
    13441 cgcaggctgt tacccctgtg gccggtttcg ggcgcatatt gccatcacgg cagcctgacg
    13501 cccgttttca ccttacttcc ggttacgcca ccagccgaca atcgctgcgg taataattcc
    13561 cgccaggatc ggtgccgcca ggtcgtgcca gaaagtcatg gcaaactgcg cgagcgtcat
    13621 atagccgcct tgttgtaatg acaacatttt gcggctattc ttgaagtgtc tggtttcaag
    13681 attagccccc gttctgttgt caggttttac ctctcaacgt gcgggggttt tctctttcca
    13741 gcaaccaatg ccaccaggga taaagccccc gcaacattgc gcctcaccgg ataattccgg
    13801 cttggtgtgg atactacgtc tcaattcatc ttcacttcat ccctgaaatg tttgcaataa
    13861 agagtacatt ccggcttttc aacagctgtt gcagtcgttt catgagtgct ctggatgatg
    13921 cttccagctc gggttgccaa tatttacttg tggaagagat aaagacaaaa atggccgcag
    13981 gctgttaccc ctgcggccgg tttcgggcgc atattgccat cacggcagcc tgacgcccgt
    14041 tttcacctta cttccggtta cgccaccagc tgacaatcgc tgcggtaata attcccgcca
    14101 ggatcggtgc tgccaggtcg tgccagaaaa tcatggcaaa ctgcgcgagc gtcatatagc
    14161 cgccttgttg taatgacaac attttgcggc tattcttgaa gtgtctggtt tcaagattag
    14221 cccccgtttt gttgtcaggt tttacctctc aacgtgcggg ggttttctct ttccagcaac
    14281 caatgccacc agggataaag ccccgcaaca ttgcgcctca ccggataacg ccggcttggt
    14341 gtggatacta cgtcgcaatt catcttcact tcatccctga aatgtttgca atgaagagta
    14401 cattccggct tttcaacagc tgttgcagtg gtttcgtgca gggtgtggta caggctcgca
    14461 attctgatta acgacctgtc caggtagtat gaagaaatac aataagcagg aatttatatt
    14521 atctcccccg attaccgtca tcggaggaga tataactgtc aggcaaatat cgtcatcaaa
    14581 taggcggcaa acagtgccag atgcgctgcg ccattgagca cgttagtacg tccggtggag
    14641 aaggagatat ggcacagcac taaagaggcc accatcacca ccatttctgg cgcaccaagt
    14701 gcaaactgca attcgttacc cgtcataaag gcaattagcg tgacgacagg tacggtaagc
    14761 gaaatggttg ctaacactga accaaagaac agattcatcg cgcgctgaac ctggttgttc
    14821 aacactgctt ttaatgcacc taaaccttcc ggcgacagaa tcaacagtgc caccaggaag
    14881 ccagtaaagg cgacaggggc attcatgctg tcgagcaatg tctccagcga gctggcgttc
    14941 attttggtca ccgcaataac ggcaatcaga tggataatca accagatagc atgccacagg
    15001 ctgctatggg cagacggttt accgtgatgc gggtcgtcat catcactgtc atcttcgtgc
    15061 tcgtagacaa acaaactttg atgcgttttg gtctggatca gcaaaaatac gccatacatt
    15121 gccgcagaaa ttaatgctac cagtaacgcc tgaccggttg aaaaattcgc cgcaggcaga
    15181 gccattggaa ataccagtac gattatcgcc agggggaaca gcgcaattaa atactgcttg
    15241 ataccaaaca gattcatata ttgggtggca aacttacgac cgcccaacaa taatgaaaag
    15301 ccaaccagcc caccggtaac aatcataatg attgaataga gcgtatcacg cattagcgtt
    15361 ggcgcggcgt cgccggttgc cattaaagct gaaatcaaac tgacttcaag aataaccact
    15421 gaaaggctaa gaataagcga accgtaaggt tctcccaggc gatgggctaa tacgtccgca
    15481 tgacggacaa cactaaaggc gctacttaaa ataccaataa gcgcaagaag attgatggca
    15541 atgaccactg gtagtgtctg gctgcttccc cacaggaaca gcactaccag cgccagaacc
    15601 gggaaaataa gcgaagtctc cttgtggcgg gtttttaccg cctcttgagc atttgacatt
    15661 atggttatcc ctttgcagat gaatttatcg aaaatgtaaa aaataggtag gaaaaataac
    15721 agaaagtgtc tggatatcgg taacatttta cgaattttta ccccgctgtc gattttttac
    15781 tcattggggc ataaaaataa gtattacgtt tagacaatgt ttgttttagc gtttcttaag
    15841 aagagtctga cctgaaaatt cttatgtttt ggcaagagta gatattgttg accacactta
    15901 atgttcaact ttgtaaaagg agtcaacgat gccgtataaa acgaaaagcg atctgccgga
    15961 aagcgtaaag cacgttctac cgtctcatgc ccaggatatc tataaagaag cgttcaacag
    16021 cgcatgggat caatataaag ataaagaaga tcggcgtgat gacgccagtc gcgaagaaac
    16081 cgcgcataaa gtggcctggg ctgctgtgaa gcatgaatat gccaaagggg atgatgataa
    16141 atggcataaa aaatcgtaaa accggtcgct tagttaaagc tattcgtgcg gtgttgcctt
    16201 gcaagtggtc cgtggattgc atattgtccc gttagtggtt tcaaaatgag cagtaaaaat
    16261 gtccggaaga caccaaaaag ttgtcgcagg gaagtatgca gtggcggagg tgtaaggtga
    16321 taacgcgtga tttcttgatg aatgccgatt gtaaaacggc atttggtacc attgaagaat
    16381 cactcttatg gtcagcagaa caacgggcgg cttcgctggc ggcgacgctg gcttgtcgac
    16441 ctgatgaggg accggtgtgg atcttcggct atggatcgtt gatgtggaat ccggcactgg
    16501 agtttaccga atcgtgcacc ggtacactgg ttggatggca tcgcgcattt tgcctgcgcc
    16561 tgaccgccgg gcgcgggact gcgcaccagc cgggacggat gcttgcactg aaagagggcg
    16621 gacgcaccac aggcgtcgcc tatcgactgc cagaagagac gctggagcag gaactaaccc
    16681 tgttgtggaa gcgagagatg attaccggct gttatctgcc aacctggtgt cagcttgatc
    16741 ttgatgatgg acgcacagta aacgccattg tgtttattat ggacccgcga catccagaat
    16801 atgaatctga tactcgcgct caggtcatcg cgccgttgat tgcggcggcg agcggtccgc
    16861 tgggaaccaa cgcacaatac ctgttttcac tggaacagga gcttatcaaa ctgggaatgc
    16921 aggacgatgg gctgaatgat ttgctggtat cggtaaaaaa actgctggcg gagaattttc
    16981 cggatggtgt gttacgtccg ggattcgcct gagtaaactt cccgcatagt ggggcgtcag
    17041 acgccccctc aaacattaaa atgtgagcac tttatcggct gacagcgtcc attgcgccag
    17101 ttccacaaga gtaccgattt ccaccccatc aatcagagga agtgtactaa tcccgcgccc
    17161 gtcggtacag gttttgcaca atttcaccgg tacattctga gcggtaagga tctccagcat
    17221 ttgctgaatg ttgtagcctt cccctggttt ttgcccgcgc aacccggctg tgaccgcatc
    17281 agacatgagg aacagacgca gatccagatt gctctcctgc tctcgtaacg caatggccag
    17341 ccgcaagctg ttaaacaagg attcgctccc gtaaggtgcg ccattggcaa cgatcacgat
    17401 tttttgcatt atttactcct gtattcaggg aattagacac tcatcttcta tcttactgct
    17461 tctgcagcgt ctgaccaatc ggtcacattt ttaaggattt tcctgaaagc gcgagaaaat
    17521 acgacaaaag ttgccagtaa tcgttattct ttaaggctat ggtttttcat tattaccgga
    17581 agttaccgac gttttgagcc gtttcgttcc tcgcattatc ccgttttatt tactcttgct
    17641 tgtagcaggc ggtacagcta acgcacaatc taccttcgag caaaaagcgg caaatccctt
    17701 tgataataac aatgatggtc tgccggattt aggcatggct cccgaaaatc atgatgggga
    17761 aaaacacttt gctgaaattg tgaaagattt cggcgaaacc agtatgaatg ataacgggct
    17821 ggatactggc gagcaggcaa aagctttcgc attgggaaaa gtccgcgacg cgcttagtca
    17881 acaggttaat cagcacgtag agtcctggct atcaccgtgg ggaaatgcca gtgttgacgt
    17941 caaagtggat aacgaaggac atttcaccgg cagtcgtgga agctggtttg tgccgttaca
    18001 agataatgat cgttatctca cctggagcca gcttggtctt actcagcagg ataatgggtt
    18061 ggtgagcaat gtgggcgttg ggcaacgctg ggcgcgcggc aactggctgg tgggttataa
    18121 cactttttat gacaacttgc tggacgaaaa tcttcagcga gcgggctttg gtgccgaagc
    18181 gtggggcgaa tatttgcgat tatcggcaaa cttttatcag ccgtttgctg catggcatga
    18241 acagacagcc acgcaggaac aacggatggc gcgcgggtac gacctgacag ctcggatgcg
    18301 catgccgttc tatcaacacc tcaataccag tgtcagccta gaacagtatt ttggtgatcg
    18361 tgttgatttg tttaactctg gtacgggtta tcacaatccc gtcgcgttga gtctgggatt
    18421 aaattacacc cctgtgccat tagtcactgt gacggcccag cataaacagg gtgaaagtgg
    18481 cgaaaatcaa aataacctcg ggctgaatct taattaccgc tttggtgtac cgctcaaaaa
    18541 acaactttct gcgggcgagg ttgccgaaag tcagtcgtta cgtggtagtc gctatgacaa
    18601 tccgcagcga aataatctac cgactcttga gtaccgacag cgaaaaacgt taacggtgtt
    18661 tctggcgaca ccgccgtggg atctaaaacc tggcgaaaca gtgccgctga aattacaaat
    18721 ccgcagtcgt tacggtattc ggcaactgat ttggcagggc gatacgcaga tattaagttt
    18781 gacgccgggc gcacaagcca acagcgcgga gggctggacg ctgatcatgc ctgactggca
    18841 gaacggggaa ggggcaagca atcactggcg attgtctgtg gtggtggaag ataaccaggg
    18901 gcagcgtgtc tcctccaatg agatcacgct aacgcttgtc gaaccgttcg atgcattgtc
    18961 aaacgacgaa ctgcgctggg aaccgtaatc agaaaatgcg ctcctgatgc acccataccg
    19021 ctgcttccac gcgagacttg agcttcattt tcttcagcat gtgcttgacg tgcactttta
    19081 ctgtgctttc ggtgatatcc aggcggcggg caatcatctt gttcggcaaa ccctgggcaa
    19141 tcagcttgag aatatcgcgc tcgcgtgggg ttaactggtt aacatcgcgc tcagtagtgg
    19201 cacggttagc gcgcaagctg gcggccagaa caggcgttaa tgcttcgctt aataccattt
    19261 cgccagcagc tgcctgatgc aatgctttca gcagatcttc cggttccata tcttttaaca
    19321 gatagccatc cgcgccgcgt ttcagtgcgg tgaccacatc ttcttcatgg ttagagacgc
    19381 tgaataccac aatgcgccct gagagggact tttcgcgcag tttatccagc gtttccagac
    19441 cgttcatgcc gggcatattg agatctaaca ggatcagatc gggatcaaga gactccgcca
    19501 gttcaatacc ctgttcgcca ttactcgctt cgccaaccac ggtgatatct ggtgccatac
    19561 tgataagctg ttttacgcca gttcgcagca tcgggtgatc gtcaatcagc aggatagtag
    19621 ccggttcctg attactcatg ggtatctcct tggacgtctg tgaaagtttt ttcgggaata
    19681 aaggtgacca ccacttcggt gccacctgat tcacgacggc ggacgcggca atcgcctcgt
    19741 aaactttgcg cacgatcgcg cattattatc atgccgtagt gattgctgcg gatggcattt
    19801 tcaggcacgc cgcagccgtt atcctggacg gtcagtttga cctgattatc gttttgcgcc
    19861 accgtcacca cgacttcact cgcttgcgaa tgtttgaggg cgttacttaa tgcctcacgg
    19921 gcaatttgca acaagtggat tgcctgatgc gaaggcacca ggcgaggcgg caattgataa
    19981 tccagcttca ccgggaagcc aaatttggcg ctgtactctt cgcaactcgc ctccagcgcc
    20041 ggacgtaatc caggctcggt gagctgcaag cggaatgtgg tgagcaattc acgcaactgc
    20101 gcccaggatg cattcagttc gttacggatc tgacttaaca gttcgcggct gctttctggc
    20161 agcgcatcgc cctgcatctg taaacaactc acctgcatct tcatgcaaga gagagattgg
    20221 gcaatagaat catgcagttc gcgcgcaatg gtggcacgct cttccatcac gatcaactgt
    20281 tgctgacgtt cctgatggcg atccagcgcc agcgtggcgg tgagttgttc aaccagggta
    20341 tccaccagtt gttgttgatc atggctaaga tgacgcccct gcggcagggt cgccagcaaa
    20401 ataccgtact gcgtatgaga gtcagccagc cgccacttca gggtcgtgcc gcgatcacca
    20461 acgggtaata cgccgcgcgg gcagagctgg cagcctttat catcacaagt catatctggc
    20521 tggcaggtaa actcctgatg attctcttca tcatcagtgt catacacccg caattcgata
    20581 tcacgtagca gggttaaatt ctgtaagccg ttgagtacag gtgacaggcg ttcacacagc
    20641 ggggcgcggg aatgcaaacg gcggttagcc tgccataaaa aagagaggat ctgattttta
    20701 tgctccagcc cggcggtttt ctcctgaacc cgctgctcaa gtacggcata actttcggcc
    20761 agttctgcag acatattgtt caacgcagtt ccaagcatcg ccatttcgtt gcgcccgctg
    20821 atgtttgcgc gttgggtaaa atcgcgatga ctgacggcac tcgccattgc cagcagttgc
    20881 cgccacggtt gtagcagtcg cgcccgcaac cagataatag tgaacaccag taaaagtgcc
    20941 ataaataccg ccattacccg atggaccagt accactgtct cgatgcgcat ttccgtggtg
    21001 cggtcaaaac cagataccag ttgatcaagc ccggcaacaa actggctgac atccgctgac
    21061 accgtttctc ggttttgtgc acgcatcagc gcagggatca gttcattacg ccagtaatct
    21121 tgtaaaccct gtaattgcgc cagttgtccg tctcgttctg ctgctcgagt caactcggcg
    21181 ctaaatgccg tttgttccat ctctttaatt aagggcttgt ctttctcgct taatggcact
    21241 gccgccaaca gacggtaact ttgcatgcgc agcgatcccg ctttgttgat cgcatgggcg
    21301 ctgccctgaa cgccttgcac cagccagcca gaaaccgcca tccctgccag tccaatagca
    21361 gtagaaagca acacaataag cgcaacctga ttaaccaggg tgagcggaga gagacaacgt
    21421 ttaagcatgt aaacctcttc cttcaggctt taaatgagca ataaccttaa tgaatgtgac
    21481 gatacattct ggaatggcag tattctcggc tattggctga agtataccca tacccggaaa
    21541 gagttactcc ttatttgccg tgtggttagt cgctttacat cggtaagggt agggatttta
    21601 cagcaccgtg aaaaatctca taatttttat gaagtcactg tactcactat gggtaatgat
    21661 aaatatcaat gatagataaa gttatcttat cgtttgattt acatcaaatt gcctttagct
    21721 acagacacta aggtggcaga catcgaaacg agtatcagag gtgtctatga gtcactcatc
    21781 cgcccccgaa agggctactg gagctgtcat tacagattgg cgaccggaag atcctgcgtt
    21841 ctggcaacaa cgcggtcaac gtattgccag ccgcaacctg tggatttccg ttccctgtct
    21901 gctgctggcg ttttgcgtat ggatgttgtt cagcgctgtt gcggtgaacc taccgaaagt
    21961 cggctttaat tttacgaccg atcagctatt tatgttgact gcgctgcctt cggtttctgg
    22021 cgcgttatta cgtgttccat actcctttat ggttcctatc ttcggtggtc gtcgctggac
    22081 ggcgttcagc accggtattc tgattattcc ttgcgtctgg ctgggttttg ccgtgcagga
    22141 tacctccacg ccttatagcg tcttcatcat catctctctg ctatgcggct ttgctggcgc
    22201 gaacttcgca tccagtatgg caaacatcag cttcttcttt ccgaaacaga agcagggtgg
    22261 cgcgctgggt ctgaatggtg gtctgggaaa catgggcgtc agcgtcatgc agttggttgc
    22321 tccgctggtg gtatcactgt cgattttcgc agtatttggt agccagggcg tcaaacagcc
    22381 ggatgggact gagctgtatc tggcgaatgc gtcctggata tgggtgccgt tccttgccat
    22441 cttcaccatt gcggcgtggt ttggcatgaa cgatcttgct acctcgaaag cctccatcaa
    22501 ggagcagttg ccggtactca aacggggtca tctgtggatt atgagcctgc tgtatctggc
    22561 aaccttcggc tccttcatcg gcttctccgc gggctttgca atgctgtcaa aaacgcagtt
    22621 cccggatgtt cagattctgc aatacgcttt cttcgggccg tttattggtg cgctggcgcg
    22681 ttctgcaggt ggtgcattat ctgaccgtct gggcggaact cgtgtcacgc tggtgaactt
    22741 tattctgatg gcgattttca gcggcctgct gttcctgacc ttaccgactg acgggcaggg
    22801 cggaagcttc atggcgttct tcgcggtctt cctggcgctg ttcctgacag ctgggctggg
    22861 tagtggttcc actttccaga tgatttcagt gatcttccgt aaactgacaa tggatcgcgt
    22921 gaaagcagaa gggggttctg acgaacgtgc gatgcgtgaa gcggcaaccg acacggcggc
    22981 ggcgctgggt ttcatctctg cgattggcgc gattggtggc ttctttatcc cgaaagcgtt
    23041 tggtagctcg ctggcattaa cgggttcgcc agtcggcgca atgaaggtat ttttgatttt
    23101 ctatatcgcc tgcgtagtga ttacctgggc ggtatatggt cggcattcta aaaaataaac
    23161 cgttactcgt catacttcgg gttacatgtg ctgcggctgc gttcattcac cccagtcact
    23221 tactttagta agctcctggg attcattcac ttgccgcctt cctgtaaacc gaattatata
    23281 gagtaaaata tttgattatc ctttgcgcgg catgatgtcg cgcttttttt atgcgtcatt
    23341 tag
//
LOCUS       DAPHKZ010000069        22502 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.069, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000069 DAPHKZ010000000
VERSION     DAPHKZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22502
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.069"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            213..1112
                     /gene="yegS"
                     /locus_tag="RH288_002808"
     CDS             213..1112
                     /gene="yegS"
                     /locus_tag="RH288_002808"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HDV4031849.1"
                     /translation="MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKG
                     DAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATS
                     VGIPEALDKALKLAIAGDAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
                     SVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALIND
                     SLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHDITFNLDGEPLSGQ
                     NFHIEILPAALRCRLPPDCPLLR"
     gene            complement(1194..1967)
                     /locus_tag="RH288_002809"
     CDS             complement(1194..1967)
                     /locus_tag="RH288_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV4031850.1"
                     /translation="MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLE
                     QKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVI
                     LDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
                     IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNR
                     RGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV"
     gene            complement(2073..3113)
                     /gene="gatD"
                     /locus_tag="RH288_002810"
     CDS             complement(2073..3113)
                     /gene="gatD"
                     /locus_tag="RH288_002810"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDV4031851.1"
                     /translation="MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR
                     IFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQ
                     CAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAKGCE
                     NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP
                     QMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKI
                     LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFTQAVRDIA
                     RNAMPGKVLLIP"
     gene            complement(3161..4516)
                     /locus_tag="RH288_002811"
     CDS             complement(3161..4516)
                     /locus_tag="RH288_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol permease IIC component"
                     /protein_id="HDV4031852.1"
                     /translation="MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIG
                     IGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPI
                     AILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKL
                     GDWFARDTRNFFELEGIAIPHGTSAYMGPIAVLVDAIIEKIPGVNRIKFSADDIQRKF
                     GPFGEPVTVGFVMGLIIGILAGYDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAK
                     QARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILIAVCVPGNQVLPFGD
                     LATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGG
                     MVASMDQGGSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKVVLA
                     E"
     gene            complement(4520..4804)
                     /gene="gatB"
                     /locus_tag="RH288_002812"
     CDS             complement(4520..4804)
                     /gene="gatB"
                     /locus_tag="RH288_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HDV4031853.1"
                     /translation="MKRKIIVACGGAVATSTMAAEEIKELCQNHNIPVELIQCRVNEI
                     ETYMDGVHLICTTAKVDRSFGDIPLVHGMPFISGVGIEALQNKILTILQG"
     gene            complement(4835..5287)
                     /gene="gatA"
                     /locus_tag="RH288_002813"
     CDS             complement(4835..5287)
                     /gene="gatA"
                     /locus_tag="RH288_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HDV4031854.1"
                     /translation="MTNLFVRSGISFVDRSEVLTHIGNEMLAKGVVYDTWPQALIARE
                     AEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVHFQQADDDNDVEVSLVIALI
                     VENPQQQLKLLRCLFGKLQQPDIVETLITLPETQLKEYFTKYVLDSDE"
     gene            complement(5297..6559)
                     /gene="gatZ"
                     /locus_tag="RH288_002814"
     CDS             complement(5297..6559)
                     /gene="gatZ"
                     /locus_tag="RH288_002814"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
                     /protein_id="HDV4031855.1"
                     /translation="MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIE
                     ATSNQVNQFGGYTGVTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAA
                     MEKSVELVKEYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCFAAESVATDCQ
                     REQLSYVIGTEVPVPGGEASAIQSVHITHVEDAANTLRTHQKAFIARGLTEALTRVIA
                     IVVQPGVEFDHSNIIHYQPQEAQPLAQWIESTRMVYEAHSTDYQTRTAYWELVRDHFA
                     ILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGF
                     NDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQS
                     GGLSAIPHQLIMDKIYDVLRAYRYGCAE"
     gene            complement(6588..7442)
                     /gene="gatY"
                     /locus_tag="RH288_002815"
     CDS             complement(6588..7442)
                     /gene="gatY"
                     /locus_tag="RH288_002815"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDV4031856.1"
                     /translation="MHVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAP
                     VIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVM
                     IDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQA
                     REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDI
                     QQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIA
                     DCGCEGRA"
     gene            complement(7752..8804)
                     /gene="fbaB"
                     /locus_tag="RH288_002816"
     CDS             complement(7752..8804)
                     /gene="fbaB"
                     /locus_tag="RH288_002816"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HDV4031857.1"
                     /translation="MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQL
                     ANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKITIA"
     gene            9061..10338
                     /locus_tag="RH288_002817"
     CDS             9061..10338
                     /locus_tag="RH288_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4031858.1"
                     /translation="MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQMLGYADISPT
                     NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYPEPVNGLTFNWSGMWTFGAVMIAII
                     AVLFMIFFRESDNEITAIKVDDRDIALTQGEVK"
     gene            10335..11339
                     /locus_tag="RH288_002818"
     CDS             10335..11339
                     /locus_tag="RH288_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HDV4031859.1"
                     /translation="MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPDLIGRNILDWALRFDAFNKN
                     VLGPTSKIALNAIRDGKPVAELENNGVTNGAAMRVSPLGCLLPARDVDSFIDDVALAS
                     SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAAR
                     LEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAV
                     "
     gene            11336..12301
                     /locus_tag="RH288_002819"
     CDS             11336..12301
                     /locus_tag="RH288_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDV4031860.1"
                     /translation="MSGARLHTLLPELTSRQPVMVVGAAVIDVIADAYALPWRGCDIE
                     LKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGVWAEIIRNRMAKEGLISLIDNAE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNRQWLARLTVAPGSLLYFSGYQLASPCGEL
                     LVEWLEKLQDVTPFIDFGPRIGDIPDALLARIMACRPLVSLNRQEAEIAAERFALSAE
                     ITTLGKQWQEKFAAPLIVRLDKEGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVL
                     AGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKNV"
     gene            complement(12275..13021)
                     /locus_tag="RH288_002820"
     CDS             complement(12275..13021)
                     /locus_tag="RH288_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDV4031861.1"
                     /translation="MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHG
                     NILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRSRGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVI
                     KQVALDQQQRPIEYSISHCRSDLYVFVCEE"
     gene            complement(13073..13891)
                     /locus_tag="RH288_002821"
     CDS             complement(13073..13891)
                     /locus_tag="RH288_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HDV4031862.1"
                     /translation="MQLRITSRKKLTSLLCALGLISIVAIYPRQTVNFFYSTAIQIKD
                     YIHFYGYRPVKSFAIRIPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKAT
                     EGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVL
                     DVEERGKLSAKELRKRVSQWLKMVEKSTGKKPIIYSGAVFYHTNLAGYFNEYPWWVAH
                     YYQRRPDNDGMAWRFWQHSDRGQVDGINGPVDFNVFNGTEEELQAFVDGIKETP"
     gene            complement(13956..14756)
                     /gene="thiD"
                     /locus_tag="RH288_002822"
     CDS             complement(13956..14756)
                     /gene="thiD"
                     /locus_tag="RH288_002822"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDV4031863.1"
                     /translation="MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQNV
                     VLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARTEQEMLE
                     QGRSLLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTAPRIMTKNTHGTGCTLSAA
                     LAALRPRHTNWADTVQEAKSWLSSALAQADTLEVGHGIGPVHHFHAWW"
     gene            complement(14753..15541)
                     /gene="thiM"
                     /locus_tag="RH288_002823"
     CDS             complement(14753..15541)
                     /gene="thiM"
                     /locus_tag="RH288_002823"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDV4031864.1"
                     /translation="MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLAL
                     GASPAMVIETEEASQFAAIASALLINVGTLTQLRAQSMCAAVEQAKSSQTPWTLDPVA
                     VGALDYRRRFCLELLSHKPTAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTL
                     ARETGAIVVVTGEMDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVATCCALPGDTL
                     ENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA"
     regulatory      complement(15576..15672)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15764..16036)
                     /gene="rcnR"
                     /locus_tag="RH288_002824"
     CDS             complement(15764..16036)
                     /gene="rcnR"
                     /locus_tag="RH288_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HDV4031865.1"
                     /translation="MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLIREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK"
     gene            16157..16981
                     /gene="rcnA"
                     /locus_tag="RH288_002825"
     CDS             16157..16981
                     /gene="rcnA"
                     /locus_tag="RH288_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
                     /protein_id="HDV4031866.1"
                     /translation="MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIA
                     IKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIIGTA
                     FWMFWRTWRGERNWLENMHGHDYEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHAND
                     IKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLA
                     LTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR"
     gene            17200..17538
                     /gene="rcnB"
                     /locus_tag="RH288_002826"
     CDS             17200..17538
                     /gene="rcnB"
                     /locus_tag="RH288_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416610.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HDV4031867.1"
                     /translation="MTIKNKMLLGALLLVTSAAWAAPATAGSTNTSGISKYELSSFIA
                     DFKHFKPGDTVPEMYRTDEYNIKQWQLRNLPAPDAGTHWTYMGGASVLISDTDGKIIK
                     AYDGEIFYHR"
     gene            complement(17620..18654)
                     /locus_tag="RH288_002827"
     CDS             complement(17620..18654)
                     /locus_tag="RH288_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="HDV4031868.1"
                     /translation="MEIRIMLFILMMMVMPVSYAACYSELSVQHNLVVQGDFALTQTQ
                     MATYEHNFNDSSCVSTNTITPMSPSDIIVGLYNDTIKLNLHFEWTNKNNITLSNNQTS
                     FTNGYSVTVTPAASNAKVNVSAGGGGSVMINGVATLSSASSSTRGSAAVQFLLCLLGG
                     KSWDACVNSYRNALAQNAGVYSFNLTLSYNPITTTCKPDDLLITLDSIPVSQLPVTGN
                     KATINSKQGDIILRCKNLLGQQNQTSRKMQVYLSSSDLLTNSNTILKGAEDNGVGFIL
                     ESNSSPVTLLNITNSSKGYTNLKEIAAKSKLTDTTVSIPITASYYVYDTNKVKSGALE
                     ATALINVKYD"
     gene            complement(18670..21150)
                     /locus_tag="RH288_002828"
     CDS             complement(18670..21150)
                     /locus_tag="RH288_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV4031869.1"
                     /translation="MLRMTPLASAIVALLLGIEAYAAEETFDTHFMIGGMKDQQVANI
                     RLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSREVIKRLGINSDNFASGK
                     QCLTFEQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYL
                     SQYYSDYKASGNNKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGF
                     AQLLGTLRVGDMYTSSDIFDSVRFRGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVT
                     IEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQ
                     PGVSKYDLAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGAGW
                     NTRIGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRT
                     FNDHVWANNKDNYRRDENDVYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLW
                     RDYWGRSGSSKDYQLSYSNNLRRISYTLAASQAYDENHHEEKRFNIFISIPFDWGDDV
                     STPRRQIYMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSHQHQGNETTAGANL
                     TWNAPVATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDA
                     YVNGQKYRTTNRNGVVIYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVL
                     VNFDTDQRKPWFIKALRADGQSLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPSSVN
                     VAIDKQQGLSCTITFGKEIDESRNYICQ"
     gene            complement(21166..21840)
                     /locus_tag="RH288_002829"
     CDS             complement(21166..21840)
                     /locus_tag="RH288_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV4031870.1"
                     /translation="MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQG
                     NRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKES
                     IFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
                     LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGN
                     YISDKI"
     gene            complement(21920..22462)
                     /locus_tag="RH288_002830"
     CDS             complement(21920..22462)
                     /locus_tag="RH288_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4031871.1"
                     /translation="MKRSIIAAAVFSSFFMSAGVFAADVDTGTLTIKGNIAESPCKFE
                     AGGDSVSINMPTVPTTVFEGKAKYSTYDDAVGVTSSMLKISCPKEVAGVKLSLITNDK
                     ITGNDKAIASSNDTVGYYLYLGDNSDVLDVSAPFNIESYKTAEGQYAIPFKAKYLKLT
                     DNSVQSGDVLSSLVMRVAQD"
BASE COUNT         5690 a         5705 c         5187 g         5920 t
ORIGIN      
        1 tttagttgaa tattaggtat atgctctttt ttgaaattta tcggtggcag ccgttagtat
       61 tcgctgtccc cattgcaagc tcctggtggt aaccactgaa tcctccatac ttgaactgac
      121 tttttatcct ccgactttca tcctgttctg actccacctt ttgttttctg ctctacacta
      181 tctacagacc aatcataaag gcacatacga tcatggcaga atttcccgcc agcttactga
      241 ttcttaatgg caaaagtact gacaatctac ccttgcgcga agcaattatg ctgttgcgtg
      301 aggaaggaat gacgatccat gtgcgggtca cctgggagaa aggcgatgcc gcacgatatg
      361 tagaggaggc ccggaagttg ggcgtcgcaa cggtgattgc cggtggtggc gatggcacca
      421 ttaatgaagt ttctacggcg ttgattcagt gtgaggggga tgacataccc gcgctgggaa
      481 ttttgccatt aggaaccgcc aatgattttg ccaccagtgt agggattcct gaggcactgg
      541 ataaggcgct gaaactggca attgccggtg acgccattgc gatagatatg gcgcaggtca
      601 acaaacaaac ctgttttatt aatatggcga caggcggatt tgggacgcgt attaccacag
      661 aaacgccgga aaaattaaaa gccgcgctgg gtagcgtctc ttacatcatt catggcttaa
      721 tgcgtatgga tactctgcaa ccggaccgtt gtgaaatccg cggtgaaaac tttcactggc
      781 aaggtgacgc cctggtcatt ggtattggta acgggcgtca ggccggtggc ggtcagcaat
      841 tgtgtccgaa cgcgttaatt aacgatagct tgctgcaact gcgcattttt accggcgatg
      901 aaatacttcc ggctctcgta tcaaccttaa aatctgacga agataacccg aatattatcg
      961 aaggcgcttc gtcgtggttt gatattcagg caccacacga catcaccttt aatcttgatg
     1021 gcgaaccgtt gagtgggcaa aattttcata ttgaaatact tccggcagcg ttgcgttgtc
     1081 gattaccacc agattgtcca ctgttgcgtt aatcaaacta ttctctcttg aaccagggag
     1141 aatccgtaat gccggatgcg gtgtaaacac cttatccggc atacagaaca atactacacc
     1201 gtaattaatt ttacccgtgt cttctgcaat gccagtttat ccacctctga tacagcatca
     1261 tcggtaataa taatgtcaat tttttcgatt ggcagtacct gattaaaacc gcgacggtta
     1321 aatttcgatg aatcgagaac ggcaatcact ttattagcgg cggtgaccat cgcaccgcta
     1381 atcgaataac cttcattaaa ggtcgtaata ccattaaccg catcaatacc atcagcaccg
     1441 acaaacatta aatcggcatt aatatcctgc agggaacgtt cagcaataga tccatgcata
     1501 gatcgcgttt tatggcggac cgtgccaccg cagacgacca gagtaatgtc tttattttcg
     1561 gaaagggcaa acgcagccgg gagactgttg gtaatcaccg tgatattttt agcggtcatt
     1621 aatccttcgg cgataagcat tgtggtactt ccgctgtcga gaataacggt catcccttca
     1681 tggatcattt tgactgccgc ctgcgctatt ctgtttttgg gcgcgctggc gagctgaaat
     1741 cgctctttaa acccgacttc ctgggtctcg gtttcactat taccggacat tattttcgcc
     1801 gcaccgccat gaaagcgcgt aaccacgcct ttttgttcga gaaagcgcaa atcggcacgg
     1861 attgtcgctt ccgaggcagc aaatactccc gccagatcct gaacaagcac ggttccctgt
     1921 tcattcacta attggatgat cttattcctt cgctcgaatg aattcatcgt catttaccca
     1981 tattcaattg tggctagtgt aaacgaaggg ggaccattgg tgaatgatct gttttgcaca
     2041 ataccgggcc agcatcacgc tggcccgcgg tttcatggaa tgagcaacac tttgcccggc
     2101 atggcattac gagcgatgtc acgcaccgcc tgggtgaagc tttcaaagct tccacggtga
     2161 gcgattaatg gctccaggct taacttacgt tctgtcagca accggctcgc cgtttcccac
     2221 tcctgccccg gccaagggct ggaatagttc atccaactgc cgataaccgt cagctcttta
     2281 cgcaatattt tgccaaacgt tgccgatgtt aaatgcagat cctgatgcaa cgtgcccacc
     2341 agcgccagtt gggcatgagg accggcaatc tctaccgcca gttcgacagt ttgcggtacg
     2401 ccagccgtct cgaggataag ctgattaaaa cgcagttcgc gtaaaacgct ctgcatttgc
     2461 ggcgcgctca tttcgctact gttaaatgtt tgcatcgcac cgaaagattt tgccagtgcc
     2521 agtttttctg agctaatgtc gatagccgtc acactctttg ctcccagcgc gacagcgcac
     2581 tgaatagcca gcaggccaat ggttccggca ccaataataa taacgttttt attctcacaa
     2641 cctttcgcta aatgaaaagc atgcagacca acggtaatcg gctcaataaa agccccatcc
     2701 tcaataggca tatccgtggg tagagcaaag acattttttc gcttaacgac aatatattca
     2761 gcaaatccac catcacgccg cgagccaata aaatcatatt ttgcgcactg ggaataaaac
     2821 cctttcagac actctggaca agtaaaacag ggtaataacg gcacacaggc aaccgcatcg
     2881 ccagggtgta aatcatcaac accggatccc accgcatcaa tatagccgct aaattcatgg
     2941 cctaacgtta ttggataata atgtgcacca tttttaaata tcctgggtaa atcggaacca
     3001 cataagcccg agctggcaat ttttacccgc acctcatcct gatgtttaat ttcaggaatg
     3061 acgctttctg caacgcgcac gataccatca gtatcattca ccactgattt cataaaaact
     3121 cctgattgtt aagggggata acctccccct caggtaaaaa ttattctgcg agaacgactt
     3181 tctcttgttt aataaagcca cgcgctctac gccaggtcat gaaaataccg gtcagataaa
     3241 ttgcaccgat aataatgaaa ccgggaatat tttgcgggga gaaaacctga atcagtaacc
     3301 aggtaatggg agaaccgccc tgatccattg aagccaccat acccccggct tttaacgccc
     3361 cagcattagc cgccagttgg gtgtgcaaac caatagtttg cgtcgcgatc cacagagtga
     3421 tgctcatgat gatgacaccc gagattaagg tgcggaacag atttccacga tgcacggcga
     3481 ccgccatcgc cacgaagaag ccgatggtgg caagatcgcc aaacggcagc acctgattac
     3541 ccggcacaca aacagcaatt aaaatggtga gtgggataaa aatcaggctt gccgatacca
     3601 ccgccgtatg tcccagcagc aacgccggat caaggccaat caggaactcc tgaccgccga
     3661 acttcgcctg taaacgacta cgagcctgct tagcgatggg cgttaaacca tccatgatgg
     3721 gtttaatcac ccgtggcatt agcagcatca ctgccgccgt ttttaccgcc agctgcaata
     3781 cacctttgac atcgtaaccc gcgaggatgc cgataatcag ccccatcaca aaacccacgg
     3841 tgacaggctc gccaaatgga ccaaatttgc gctgaatatc gtcggcgcta aatttaattc
     3901 ggttaacgcc tgggattttc tcgatgatag catcgaccag caccgcaatc ggccccatat
     3961 acgccgacgt accgtgcgga atagcaatac cttccagctc aaagaaattt cgggtatcgc
     4021 gggcaaacca gtcgccgagc ttataaacaa acgccgcgtg aattacgaca cctgccatcc
     4081 ctatcatcca tgaaccggtt gccagatgca gcaacgcgcc ggtgaaggtc atatgccaga
     4141 tattccagat atcaacattt accacccgcg tcatacgggt cagtaacatc gccacgttaa
     4201 ccaatatcgc aatcggaatc gccaccagcg caatttgcga agcccaggtc attggtgaag
     4261 agcccggcca gccgacatcg accacatgca gattcaggtc gaaattttcc gccatcgctt
     4321 tcgccgccgg accaatggaa tccagcatta agccaatcac aaggccaatg ccaacaaagc
     4381 caatcccgat atgcagaccc gctttaaagc aatcgcctgc cttcatgcct aatattttag
     4441 aaaaaataat gatgacaatc ggaagcatca ccgtagggcc gaggtcgaga atataacgca
     4501 tgacttctga aaacataggt cacccctgta agatagtcag aattttattt tgtaatgctt
     4561 cgataccgac accagaaata aaaggcatgc cgtgaactaa cggaatatcg ccaaaactac
     4621 gatccacttt ggcagtggtg catatcaaat gcacaccatc catataggtt tctatttcat
     4681 taacccgaca ctggattaat tcaacaggaa tattatgatt ctgacacaac tctttaattt
     4741 cttccgccgc catcgtagag gtcgcaaccg cgcctccgca agcgacaata atcttgcgtt
     4801 tcataaatag tcctttttat tgttacagag ggatttattc gtctgaatct aaaacatact
     4861 ttgtgaagta ttcctttaac tgagtttcag gaagagtaat tagtgtctcg acgatatcgg
     4921 gctgttgtaa cttgccaaat aaacagcgta aaagtttcaa ttgctgctgc ggattttcca
     4981 caatcaacgc aataaccaac gacacctcca cgtcgttatc atcatccgct tgctgaaaat
     5041 gaactttatt tgttggcctt aacagataaa tggctgacga cttagcatga atcgcctcac
     5101 aatgcggtat agcaatggcg tgctgctcaa gcattatccc ggtagggaat tctgcttctc
     5161 tggcaattaa tgcctgtggc caggtatcat aaaccacacc tttcgcgagc atctcattac
     5221 cgatatgggt taaaacttcg ctacgatcga caaaagaaat tccgctacga acaaacaggt
     5281 tagtcatata ccgtccttat tccgcacagc cgtagcgata ggcgcgcaaa acatcataaa
     5341 ttttatccat aatcagctga tgcggtattg ctgataatcc cccggactga atgcgttcaa
     5401 attgtttggg aagatactga ctaatcatgc ccagtgggat gtccacgcct tcaagattca
     5461 ccatcatcgt ttcgacgcta tttttaatcc gactatgcgg ccagtaataa cgaatacgat
     5521 ccgacaggct gtaacgaata tccagtaatg aatcgttaaa acccgtacga taatattttt
     5581 tccagtattg cggttcgtcg agcatcactt cttcaattac cgccaggcaa ccgctgcgat
     5641 tttcaggggc gataagttcc tgctcaattt gtgccagtgc aaatatcgcc tcgcgtaaag
     5701 caaaggttaa tgcgggaccg actttcaata ttgcaaagtg atcgcggact aattcccaat
     5761 aagccgtccg ggtctggtaa tcggtagaat gtgcttcata aaccattcgg gtgctttcta
     5821 tccattgcgc cagcggctgc gcttcctgcg gctgataatg gataatattg ctgtgatcaa
     5881 attccacgcc cggctgcacc acgatggcaa tcacgcgtgt taacgcctct gtcagcccac
     5941 gggcaataaa ggccttttga tgcgtacgta aagtattggc ggcatcttca acatgggtga
     6001 tgtgtactga ctgaatggcg ctggcctcac cgcccggaac cggaacttcg gtgccaatga
     6061 catagctcag ttgctcacgc tggcaatctg tcgccacact ttccgcagca aagcaaagca
     6121 cagcagctcg ttccgcaacc gtttctggtg ctaacggtat gggatccccc gcgcaggaca
     6181 ttgacgcatc aagatgaatt ttactgaaac cggcacgaac atattccttt accagctcga
     6241 cggatttttc catcgccgca tccgcatttt cttgctgcca gcagtttggc cccagatgat
     6301 cgccgccgag aataatgcgt tcgcgtgcaa acccaacttt atcggcaatc gtaaaaacaa
     6361 attcgcgaaa gtctgccggt gtcactccgg tataaccgcc aaattgattg acctggtttg
     6421 acgttgcttc aatcagcact ttgcgcgtgc tgttgcgatc aaatgccagc gccgcttcga
     6481 taaccaacgg atgggcagaa cagactgaac atatgccgat atgttcacca gctttatgcc
     6541 gggcaattaa cgttttcatg ttttttcctt attaaatggc aggtgcgtta tgccctgccc
     6601 tcgcagccac aatcggcaat cactttgctc accacatcgc gcattgcgga tttagccgac
     6661 tgcaaataat cccggggatc ggtcgcttca gggtgctcgg tcaggtaatt ttttaacgcc
     6721 tgcgagaagg catttttcag ctccgttgca acgttgattt tgcatatccc cagtttgatg
     6781 gtttgctgaa tatccttagt cgataaccct gacgcgccat gcagcaccag cggtaagttc
     6841 acccactggc gaatgttctc cagtcgagaa aaatcaagcg ccggtgcgct ggcatacatc
     6901 ccatgagccg tgccgatggc gaccgccagg gaatcaattc cggttgcctc ggcaaattca
     6961 cgcgcctgag cggggttggt ataaaaagca tcggcttcat tgacttgcac atcatcttcc
     7021 tggccgccaa gttgccccag ctccgcttcg acgctgacat caaagcgatg gcaaaaatcc
     7081 accacctctt tgacccgtga aatattttgc gcaaaaggca aatgcgaggc gtcaatcatg
     7141 actgagcgca cgccagaacg aaccttctga gcgatatcgt caaatttcgt gtgatggtcg
     7201 agatgaattg ccagtggatg gtgatattgc ttcgccatcg cgctgaccag cgccaacaga
     7261 ttttctgtac cagcatgagt aaatgtgcca ggcgttccgg cgatgatgac cggcgcatgc
     7321 aggttggcag cggtttccac caccacttgc atcgtttcga gattgtgaat attgaatgcc
     7381 ggaaccgcat aaccgccgcg ctgtgcgttg ttcagcatct gctttgtcga taccacgtgc
     7441 attttcatat cctgtcgttt gttttcgatt tcaaaatata atgaaatgat ttgtttttaa
     7501 atgtcgagat aacgatcaca aaaacgacaa tgtgaaaatt gttcgaggag taaaaggcaa
     7561 aaaaaaacgg cctcccgata gggaagccgt agcaaagtgc gcgtgttttt atgccggatg
     7621 cggtgtaaac atacgtggca gtgctatgta ggcatgataa gacgcttccg cgtcgcatca
     7681 ggcataggtt gccggatgca gtgtaaacgc cttatccgtc ctacggggtg gtgctgttcg
     7741 tatgaggcgt atcaggcaat agtaattttg ctatcgagat aaacgtcctg cacggcatta
     7801 atcagtttca cgccgtcagc catcgatttc ttgaacgcct tacgtccaag aatcagcccc
     7861 attccgccag cgcgtttgtt gataaccgca gtacgcactg catcgctgag gtcagtttca
     7921 ccgcccgcag caccgccgga gtttatcaac ccagcccgac ccatatagca gttagctaac
     7981 tgataacgca ccagatcaat cgggttttcg ctggtcaatt tgctgtaaac acgatcgtcg
     8041 gtgtaaccgt aattaattgc tttatagccg ccgttatttt ccgccatttt ttgtttgacg
     8101 atatctgcac cgatggttgc cgccagatgg tttgcctgac cggtcaggtc ggcggaaaca
     8161 tggtaatcaa cgccatcttt cttaaaggcg gagttacgca aataggccca cagcactgtc
     8221 accataccca gctcgtgcgc acgttcaaaa gccgcagaaa tttcttcaat ctggcgacgt
     8281 gactcttccg agccaaaata gatagtcgca ccaaccgcaa ccgcgcccat gttgaacgcc
     8341 tgctccacgc tggcatacag cgtttgatcg taggtattcg ggtaacttag cgtctcgttg
     8401 tgattaagtt tgacgaggaa tggaatgcga tgcgcataac gccgcgatac cgacgccagc
     8461 acgccgtaag ttgacgccac acagttacag cccgcttcga tcgccagttc aacaatgttt
     8521 ttcgggtcaa agtagagcgg gttagcagca aatgaagctc cggcagagtg ctcaacgccc
     8581 tggtcaaccg gcagaataga aagatatcct gtgccagcca gacgcccggt gttgtacaac
     8641 gtctgcatat tacgtaacac cgctggcggg cgattattgt caatcattac gcggtctacg
     8701 tagtcatgtc cggggagata aagctggtca gaaggaattg tcatacaacg gtgctgtaaa
     8761 aggttgtcgg cgtctttgcc aagcaactgc gcaatatctg tcattactat gctcccgtaa
     8821 attccgattg gatatcggct atggattgtc ctggcccgcc ttttgcgggc aatcataatc
     8881 ctggtcgtta cgggcgagtt tttccatctt ttggatgttt tttcagcgtt ttctgttggc
     8941 tcgattcatc agaaaaaatg ttagcgcggt caagttttca ccgcaaaggt atttaaaagg
     9001 tattattaag tggtattgtc atcgcgtacc ttacattacc tgtcatgaag gaattaaaag
     9061 atgaaaacaa cagcaaagct gtcgttcatg atgtttgttg aatggtttat ctggggcgcg
     9121 tggtttgtgc cattgtggtt gtggttaagt aaaagcggtt ttagtgccgg agaaattggc
     9181 tggtcgtatg cctgcacagc cattgcggcg atcctgtcgc caattctggt tggctccatc
     9241 actgaccgct ttttctcggc gcaaaaagtg ctggcggtat tgatgttcgc aggcgcgctg
     9301 ctgatgtatt tcgctgcgca acagaccact tttgccgggt tcttcccgtt actgctggcc
     9361 tactcgctaa cctatatgcc gaccattgcg ctgactaaca gtatcgcttt tgccaacgtg
     9421 ccggatgtgg agcgtgattt cccgcgcatt cgtgtgatgg gcactatcgg ctggattgcc
     9481 tctggtctgg catgtggttt cttgccgcaa atgctggggt atgccgatat ctcaccgact
     9541 aacatcccgc tgctgattac cgccggaagt tctgctctgc tcggtgtgtt tgcgtttttc
     9601 ctgcccgaca cgccgccaaa aagcaccggc aaaatggaca ttaaagtcat gctcggcctg
     9661 gatgcgctga tcctgctgcg cgataaaaac ttcctcgtct ttttcttctg ttcattcctg
     9721 tttgcgatgc cactggcgtt ctattacatc tttgccaacg gttatctgac cgaagttggc
     9781 atgaaaaacg ccaccggctg gatgacgctc ggccagttct ctgaaatctt ctttatgctg
     9841 gcattgccgt ttttcactaa acgctttggt atcaaaaagg tattattgct tggtctggtc
     9901 accgctgcga tccgctatgg cttctttatt tacggtagtg cggatgaata tttcacctac
     9961 gcgttactgt tcctcggtat tttgcttcac ggcgtaagtt acgattttta ctacgttacc
    10021 gcttacatct atgtcgataa aaaagccccc gtgcatatgc gtaccgccgc gcaggggctg
    10081 atcacgctct gctgccaggg cttcggcagt ttgctcggct atcgtcttgg cggtgtgatg
    10141 atggaaaaga tgttcgctta tccggaaccg gtaaacgggc tgactttcaa ctggtccggg
    10201 atgtggactt tcggcgcggt gatgattgcc attatcgccg tgctgttcat gatttttttc
    10261 cgcgaatccg acaacgaaat tacggctatc aaggtcgatg atcgcgatat tgcgttgaca
    10321 caaggggaag ttaaatgaaa acagaacgta ttctcggtgc tctttatggg caggcgttag
    10381 gggatgcgat ggggatgccc tccgagcttt ggccacgcag tcgcgttaaa gcacactttg
    10441 gctggattga ccgttttctg cctggaccaa aggagaataa cgcggcctgt tattttaacc
    10501 gcgccgaatt caccgacgat acctcgatgg cgctgtgtct ggcggatgcg ttactggaac
    10561 gtgaaggcaa gatcgatccg gatctgattg ggcgtaatat tctcgactgg gcgctgcgtt
    10621 tcgacgcctt taacaaaaac gtactaggtc cgacctcgaa gattgcgctt aacgccattc
    10681 gcgacggtaa acccgttgct gaactggaaa acaacggcgt gaccaacggc gcagcgatgc
    10741 gcgtctcgcc attaggttgt ttgcttccgg cgcgtgatgt tgattccttt attgatgatg
    10801 tggcgctggc gtcgagcccg acccataaat ccgatctggc agttgcaggt gcggtagtca
    10861 tcgcatgggc gatttctcgt gccattgacg gagaaagctg gtcagcgatt gttgattccc
    10921 tgccttcaat tgcgcgacat gcacagcaaa aacgcatcac taccttcagc gcctcactgg
    10981 cagcacgtct ggagattgcg ctgaaaattg tgcgcaatgc cgacggcacc gaatccgcca
    11041 gcgaacagct ttaccaggtc gttggcgcag gtaccagcac tattgagtcc gttccgtgcg
    11101 ccattgcgct ggttgaactg gcacaaaccg acccgaatcg ctgcgccgtc ctgtgcgcta
    11161 accttggcgg cgacacagac accatcggcg ctatggcgac ggcgatttgc ggcgcgttgc
    11221 atggcgttaa cgctatcgat cctgcattaa aggcggaact ggatgcggta aatcagcttg
    11281 atttcaaccg ctatgccaca gcgctggcga aatatcgtca acaacgggag gcggtatgag
    11341 cggcgctcga ttacacacgc tgctgcctga attaacctcg cgtcagccgg tgatggtcgt
    11401 cggcgcggcg gtcattgatg tgatcgccga cgcttatgcc ctcccctggc gtgggtgcga
    11461 tatcgaactg aagcagcaga gcgttaacgt tggcggctgc gcactgaata ttgccgtggc
    11521 gttaaagcgc ctcggcatcg aagcgggtaa tgccttgccg ctcggtcagg gcgtgtgggc
    11581 ggagattatt cgcaaccgga tggcgaaaga ggggttaatc agcctgatcg ataacgccga
    11641 aggcgataac ggctggtgtc tggcgctggt tgagccggat ggcgaacgca cttttatgtc
    11701 attcagcggt gtggaaaatc agtggaatcg ccagtggctg gcgcgattaa ccgttgcgcc
    11761 tggcagcctg ctctattttt ccggttatca actggcctcg ccctgcggcg aattgttagt
    11821 ggaatggctg gaaaagctgc aagacgtgac gccgtttatc gattttggcc cacgtatcgg
    11881 cgatatcccg gacgcattac tggcgcggat catggcctgt cgacctttag tatcactcaa
    11941 tcgtcaagag gctgagattg ccgccgaacg ttttgcttta tccgcagaga taacaacact
    12001 tggcaagcaa tggcaggaga aatttgccgc gccgttgatc gttcgtctcg ataaagaggg
    12061 tgcatggtat ttcagcaacg acgcttctgg ctgcattccg gcatttccaa cgcaagttgt
    12121 agacaccatt ggggcgggcg acagtcatgc aggtggcgta cttgccgggc tggcctctgg
    12181 tctgccactg gcggatgccg tattattggg caatgcagtg gcgtcgtggg ttgtcgggca
    12241 tcggggcggt gattgtgcgc caacgcgcga ggaactactc ctcgcacaca aaaacgtata
    12301 gatcgctgcg acagtggcta atgctgtact caataggccg ttgctgttgg tcaagcgcca
    12361 cttgcttgat caccagcacc ggtattttgc tatctaactg aatatgtgac tgaaactcgg
    12421 catccggcat ccgggcgcta acgcgggaac gcgtacgttg tgggtaaatg tgctggctgc
    12481 ggaaatagtc ataaagtgaa atcccgatgg catcaacatc atgaattaaa tgcgccggaa
    12541 cccacgattc ctcaatcgat accgcttctt catcgacata gcgaatacgc ttaagcaaaa
    12601 agacatcact tcctgcttcg accgccagct gctgcgcgac ttcttcggga catttcacga
    12661 cacgcttgtt aacccatagc gtatcgggct ttttcccgcg caataccacc tgctgagaaa
    12721 aacctcgcgc ttctttcaac gagtattcga agatgttgtt gatctgcgtg ccgtaaccgc
    12781 gcgaacgcgt caccacaccc tcttcttcca gcgcctgcat cgccttgcgc accgtaatgc
    12841 gcgaaacacc ggttaactga cttaaatcac gctcaccggg caaaatattg ccatgctcca
    12901 gcaccccgct gcgcacggca ttttttaccg tttcggcaaa cttaatataa agcggcgtgt
    12961 tatccgccgc taaaatacgc tcgttcaact gagcgataag ctgggtatgc gcttgttcca
    13021 tttgtctttt tcctgccggg gagtctggtg gaagtatatc actgcttctt atttaaggcg
    13081 tttctttaat cccatcaacg aatgcctgca actcctcctc tgtgccatta aacacattaa
    13141 aatccaccgg accattaatg ccatctacct gcccacggtc ggaatgctgc cagaaacgcc
    13201 aggccatgcc gtcattgtcc ggacgacgtt gatagtagtg agccacccac cacggatatt
    13261 cattgaaata gcccgccaga ttggtgtgat aaaaaacggc tcctgagtaa ataatcggct
    13321 tttttcccgt acttttttcg accattttta gccactgact tacccgcttg cgtaattctt
    13381 ttgccgataa ttttccccgt tcttctacgt ccagcacggc agggaaatcg ccttgtgaga
    13441 aatccaccgt ttgcagaaat aatcgtgcct gaaccggcgc tgctaccgac ggggagaaat
    13501 aatgatacgc cccgcgcagc aggccatttt cgcggcttag ttgccagtta cgcgaaaaat
    13561 aggggtccac cagcttttcg ccttccgtcg ccttaataaa agcaaactgt aagcggatac
    13621 cgttgtcgcg catttttgcc acccgctgcc agtcgatccg ctcctgccag cgagaaacat
    13681 ctattccgtg aatggtgtaa ctggcaggaa tgcgaatagc gaaagattta accgggcgat
    13741 aaccgtagaa atggatgtag tctttaatct gaattgctgt cgaatagaaa aaattcaccg
    13801 tctgacgcgg ataaattgca acgatggaaa ttagcccaag agcgcataat agagaggtga
    13861 gtttttttcg actggtaatt cttagctgca ttggtttcat ccctgaatgt cagtgcaaaa
    13921 gactgacaat aaccaaagca gctatagtac ggtgctcacc accaggcgtg gaagtggtga
    13981 accggaccaa taccgtgacc aacttccagc gtgtcggcct gggctaacgc cgatgaaagc
    14041 cagctttttg cctcctgtac ggtgtcagcc cagtttgtat ggcgcgggcg tagtgcagcc
    14101 aacgccgcag agagtgtaca accagtgccg tgggtgtttt tggtcataat gcgcggtgcg
    14161 gtaaaccgtt gttcaccctc gcgggtaaac agccagtccg ggctttgctc atcatccaga
    14221 tgaccacctt tcattagcac tgcgccacag cccatcgcca acagcgatcg cccttgttcc
    14281 agcatttcct gttcggtgcg cgcgtgtggc gcgtcgagca aggcggcagc ttcgggcaag
    14341 tttggcgtta ttaatgaaac ctgtggcaat aatcgactgc gcagcgtagc aaccgccgaa
    14401 ggtgaaagca gcgggtcgcc gctttttgcc agcataacgg tgtcgagtac cacgttttgg
    14461 atctgataac gttgcaaccg ttctgccacc gcttcaacaa tatcggtttc cgccaacata
    14521 ccgattttag tggtgtcgat tcgcacatcg ctgaacaccg aatcgagctg ggcggcgaca
    14581 aaatcaggct caatgcgata caccgactgt acgccacggg tattttgcgc caccagtgca
    14641 gtaataactg agcaaccata agcgccaagt gccgagaagg ttttaagatc ggcctgaatc
    14701 cccgcaccac cactcggatc agtaccggca atcgtcagag cgttaattcg tttcatgcct
    14761 gcacctcctg cgtcaattgc cagagcgcat caaggaaatg tggaacaaaa ctgcctggcc
    14821 cctcgcttct ggcgactgcg cgctctccgg cttgtttcat ccagtgacag gcagatgcga
    14881 cattttccag cgtatcgcct ggtaacgcac agcaggtagc gacaaccgcc gataatgcac
    14941 agccagttcc taccactttg gtcattaacg gatcgccacc gtgaatacca atgatacgat
    15001 gtccatcggt aacataatcc atctcgccag tgaccacgac gattgcgcca gtttcccgtg
    15061 ccagtgtttg tgcagcgggt atcgcgttag ctgcggcgtc agtggtatcc actccccgtc
    15121 caccattagc aatgccagct aatgccatga tttccgaagc attaccacgt atggcggttg
    15181 gcttatgaga cagaagttcc agacaaaaac ggcggcgata atcgagtgca ccaaccgcta
    15241 ctggatcaag cgtccagggt gtttgagagc tttttgcttg ctcaacggcg gcacacatcg
    15301 actgtgcgcg tagctgcgtc agcgtgccaa cgttaatcag caacgcactg gcaatagccg
    15361 caaactgact ggcctcttcg gtttcgataa ccatcgctgg cgatgcaccg agcgccagca
    15421 aggtattggc agtaaaggtt tgcaccacat cgttggtcat gcagtgcaca agaggggaat
    15481 gttggtgaaa aaggtgtaac gcgtgcgcag attgcgctga actcagcagg tcgacttgca
    15541 tagtttgctc ctgccataac gtgaagaagc aatgacctgg tggtccgtga cttccctacg
    15601 ctggcattat ccagatcagg tgatacgggt atttctcagc cttcacgcag aagggcaccc
    15661 cgagtcgttt ggttgcgatg ataaatcgca gaggaggatg gtaatgtcca gcgcacgcgt
    15721 tgtaaacgag gaaaaacggc agttttacaa tcgcgttaat aaattatttg atatatgaat
    15781 ccagcacctt cagaacgaca tccagatctt cttcacgttt tagctcatcc ccctggtgaa
    15841 cgatgtgttc cgtcagatga cctttaatca cttcccgtat cagaccgttt accgcgccac
    15901 ggatagcagc aatctgttgt aaaactgcag cgcattcgtg cggctcgtcg agcattttct
    15961 tgagcgccac gacctggccc tgaatcttac tggcacgcgc tttcagtttc tgtttatcac
    16021 ggattgtatg agacatggca acacctggtt aacaagaata tgaaaaatca tagcactatt
    16081 aatctactgg ggggtagtat caggtactgg gggggagtag aatcagattg ccgaattaat
    16141 actaagaatt attatcatga ccgaatttac aactcttctt cagcaaggaa acgcctggtt
    16201 cttcatcccc agcgccatct tacttggtgc gcttcatggc ctggaaccag ggcactcaaa
    16261 aacgatgatg gcggcgttta tcatcgccat caaaggcacc attaaacagg cggtgatgct
    16321 cggactggca gcaaccattt cgcataccgc ggtggtctgg ttgattgcct ttggcgggat
    16381 ggtgatcagt aagcgcttta ctgctcaatc agcagaaccg tggctccagc tgatttccgc
    16441 agtgatcatt attggcaccg cgttctggat gttctggcgt acctggcgcg gcgaacgcaa
    16501 ctggctggag aatatgcacg ggcatgatta tgagcatcat caccacgatc acgaagatca
    16561 ccacgaccat ggacatcatc accatcacga acatggcgag tatcaggatg cccatgcacg
    16621 agcccatgcc aatgacatta aacgacgctt tgatggtaga gaggtcacca actggcaaat
    16681 tttgctattt ggcttaaccg gtggccttat cccctgcccg gcagcaatta ccgtgctgtt
    16741 gatatgcatt cagttgaaag ccctgacact gggcgcaaca ctggtcgtca gtttcagcat
    16801 tggcctggcg ttaacgcttg tcaccgtagg cgttggcgca gcaatcagcg ttcagcaggt
    16861 cgcaaaacgc tggagcggat ttaacactct cgctaaacgc gccccctatt tttccagtct
    16921 gttgattggc ttagttggtg tgtatatggg cgtacatggc ttcatgggca taatgcgata
    16981 actcaatcct ttaggcttgc atgttatctt cagcccagga tgattcttaa atcagctatt
    17041 tccgctgact ctctgctcgc taaggatgct tttagggcat cctttcattt acacttttta
    17101 cgaaatcatg ggatcactaa caaaatatcg cttgtcagtt atattgtatg gcaggaaaga
    17161 tatgcgactg atattacaga tccccaaagt ggagagttta tgaccattaa aaataagatg
    17221 ttgctgggtg cgcttttgct ggttaccagt gccgcctggg ccgcaccagc caccgcgggt
    17281 tcgaccaata cctcgggaat ttctaagtat gagttaagca gtttcattgc tgactttaag
    17341 catttcaaac caggggacac cgtaccagaa atgtaccgta ccgatgagta caacattaag
    17401 cagtggcagt tgcgtaacct gcccgcacct gacgccggaa cccactggac ctatatgggt
    17461 ggcgcgtccg tgttgatcag cgacaccgac ggaaaaatca ttaaagccta cgacggtgag
    17521 attttttatc atcgctaaaa aaagccccct cggagagagg gggaaatgca gacaccttat
    17581 tatttcttat tattagccac ttgctcgtct tgcttgttat tagtcgtatt tcacgttgat
    17641 taatgcggtt gcttccagtg cgccagattt aactttgttt gtatcgtaga cgtagtaact
    17701 ggctgttatc ggaattgaaa ccgttgtatc tgtaagtttt gactttgccg caatttcttt
    17761 taaatttgtg tatcctttac tgctgttagt gatatttaaa agtgtgactg gcgaactatt
    17821 actttcaaga ataaatccta cgccattatc ttccgcacct ttcagtattg tgttgctgtt
    17881 ggttaacaag tcagaacttg ataaatacac ctgcattttc cgtgatgttt gattttgttg
    17941 acctaataaa tttttacaac gcagaataat atccccttgt ttactattta ttgttgcttt
    18001 gttacctgtg actggtaatt gtgaaacggg aatactgtct aaagtaatta ataaatcgtc
    18061 cggtttgcag gttgtggtta tcgggttgta tgacaatgtc agattaaagg aatagacacc
    18121 tgcattttgt gccaatgcat ttctgtagct atttacacat gcatcccatg acttgccacc
    18181 taataaacac agtagaaatt gtactgcggc actcccgcgt gtcgatgatg aagcactgga
    18241 taatgttgca acaccattaa tcatcactga accgccgccc cccgcagaaa cattcacttt
    18301 tgcattactg gccgcaggtg tcaccgttac cgaataacca ttggtgaaac tggtctgatt
    18361 atttgacaac gtgatgttat ttttattggt ccattcaaaa tgtaaattta atttaatggt
    18421 atcgttataa agtccaacaa taatatccga cgggctcata ggggtgatag tatttgtact
    18481 tacgcatgac gaatcattaa aattatgctc atatgtcgcc atttgtgttt gagtaagtgc
    18541 aaaatccccc tgaacaacca agttgtgctg aacagataac tcactataac atgccgcata
    18601 gctcacaggc ataaccatca tcattaatat aaatagcatt atgcgaattt ccatagaacc
    18661 acctgactat tactggcaaa tataatttct actttcatca atctctttac cgaaggtgat
    18721 tgtgcatgaa agtccttgtt gcttatcaat tgccacatta accgatgacg gtacttcatt
    18781 ggtgcgaata aataactgac ttccctggcc gacaacgcca atattatgac catggatatc
    18841 attgacttca taaccaaacg ttaatgattg cccatctgct cttaacgctt ttataaacca
    18901 tggcttgcgc tgatcggtat caaaattaac cagtacaacc gcgccgcgat aaggggcggc
    18961 aattttccgg ttgccacgta attctgcttc gctatcgctt tgcgacacat ccagcatcag
    19021 gtgattttcc cgataaggtg tcattccgtc gtatatcacc actccattac ggtttgttgt
    19081 gcgatatttt tgcccattga cataagcatc tttaattcct ggcgcattca tcacagcaaa
    19141 cgtttcggaa agacggttcg ccagattaac gccacccgac caggcgacaa tgccccctga
    19201 aacactggct ccagcctgtc gataagtact cgactgacta taactgccat tcactgtcgc
    19261 aaccggcgcg ttccaggtca aattcgcccc agctgtcgtt tcatttccct gatgttgatg
    19321 actcaggttg acaccataat tgaactgatc ccgactccct actgttcctg ataatcccgt
    19381 attatttgag gcaaacccct gatcatcaaa cgtcgttgag ttagacatat atatttgccg
    19441 acgaggcgtc gaaacgtcat caccccaatc aaagggaatc gatataaaaa tattaaaacg
    19501 tttctcttca tgatgattct cgtcataagc ctggcttgcc gcgagggtat agcttatccg
    19561 tcgcaggttg ttggaataac tcaactgata atccttacta ctgccgctac gcccccagta
    19621 atctcgccat aacgtactta atgacacaga cccccaacct tctggcaatg actggctcat
    19681 attggcggaa aagctatttt tgcggccaaa atcgttctgg taataatcgg caatgtcata
    19741 gacatcgttt tcatcacggc gataattatc tttattgttt gcccaaacgt gatcgttaaa
    19801 tgtccggtaa tcacgcgacg aataacgcca ggccgccaga ccaaaacgcg tcgacgtttg
    19861 gctcacaaat ttgttgtagg caatttgata actttgcccg tcaaacacat cgccgttgtc
    19921 ttgtttacta tgcgacttag tggcatcgac ggaaatggca ccaatgcgtg tattccagcc
    19981 agcccccaaa gtaaacgcgt aataattatt cgcgaccatc gagccaccat acagcgtcaa
    20041 taaattatta aaaccatact gataacccgc ctggacaaaa tcactttgtt tgctcgcccc
    20101 ttcaatatgg ctacgacccg ccgctaaatc atatttcgac acgccgggtt gcagcatatt
    20161 tggcaccgct gcataaggca ccagataggt ggttaccgag ccgtccgcct ctttcacgct
    20221 gacatcaaga tctgctccac caccggccaa ctgcaaatct gtaatcgcga acgggccagg
    20281 aggaacctct ttctgataaa ccacaaaacc attctgttca atagttacca gcgcgttact
    20341 ctgagcaatc ccctgcaccc gtggcgtaaa attttgtttc gagttaggca acatctgcat
    20401 atcacgaaac aaccgcacac ctctgaagcg aacagaatca aaaatatcgc ttgatgtgta
    20461 catatcaccc acgcgaagcg tgccgagaag ttgggcaaat ccacgttcca gatacagggt
    20521 attgcttttc cacacccctg gattgttatt tgttttactg aaactggcat cagaatgcag
    20581 ttgccacccc agtaaattta acccgctgtt aaaacgtaca tatgtactct tgttattacc
    20641 cgacgcttta tagtcgctgt aatactgact cagataataa gaggtataaa acgcattaat
    20701 accccgctcc cagttttccg gtggaacata gccactttcc agttcttcca cccaggcctg
    20761 cgggacactg aaatcgagac gaaaaacccc gatatcccag gtatagctcc caccctgaac
    20821 aagttgctca aatgttaaac attgcttacc gctggcgaag ttatcgctat taatgcctaa
    20881 ccgcttgata acttctcttg ataaacatgt ttcttgcggg ttgtctttaa caataatctc
    20941 atatttcccg cgccattgct tattgacata aatatcgatg tcatactgcc ccggtaaggg
    21001 ttgattatca tcaagacgaa tatttgcaac ctgctggtct ttcattccac ctatcataaa
    21061 atgggtatca aaggtttctt cagctgcata agcttcaatg ccgagcaata acgctacgat
    21121 tgctgatgca agtggggtca ttctcaacat aggcagctcc tgcaattaaa ttttgtcact
    21181 aatatagttg ccatggtcat cgataatggt cagatgccag ttatttgcat tattactttt
    21241 gacattaaca ctctgacttt ctaagggggc aatcataata gtttcataat tgactttgac
    21301 attattagct ttgacatccg aaatcgtcac ccaattagct gagtcatttt ttatcaccaa
    21361 accattgcca ctgcgattta ccagcaattt tttaaatgtc gctttattta ccggagcaat
    21421 acccgctggc cggtaaaaca acttaattct gttttgcatc gcaaacttca gtgcattctt
    21481 accttcttgc tctggactat ttggtggaat atccagaaca ttcagataaa aaatgctttc
    21541 tttattagtg ggcagtttat tcggcataat tttgattttt acttgctgcc cggaatttgc
    21601 tcctattttt gccactggtg gcgttaacat gaaaggaacc tgaatttttt ctggtggtaa
    21661 tgacgtatcg ccatcatcaa tccacgcctg cagcagcgaa gaacggtttc cctggttcat
    21721 caactgcacc atcacttctt tattttctgc cgggtaaata atgcgcgtcc cgtagataac
    21781 aattccggca tgtgcaggaa ggaccataga aaaaatgagt aaagataata atcctttcat
    21841 tttaatgcct cttaaattaa aaggccgcca tgggatagcg gccatgttta ttacctggag
    21901 aaacttacaa ttttatttat taatcctgcg ccacacgcat aaccagagaa gataacacat
    21961 cacctgattg cactgagtta tctgtcagtt tcaggtattt tgctttaaac ggaatagcat
    22021 attgaccttc cgctgtttta taactctcaa tgttaaaagg tgcagaaaca tccaggacat
    22081 cgctgttatc acctaaatag agatagtaac ccacggtatc gttgctactg gctatcgcct
    22141 tatcgttacc ggttatttta tcgttggtaa tcaacgagag ttttacacca gcaacttctt
    22201 tcgggcagct aatttttaac atgctgctgg ttacaccgac tgcatcatca taggtagaat
    22261 atttagcttt accttcaaag acagtggttg gtacagtcgg catattaata cttactgaat
    22321 caccacccgc ttcgaattta cacggagatt ctgcaatatt ccccttaata gttaatgttc
    22381 cggtatcaac gtctgcagca aatactccag cgctcataaa aaaagaagaa aagacagcgg
    22441 cagcaataat tgaacgtttc ataatatgtt ccttaataaa atttattttt ggttgttaag
    22501 ag
//
LOCUS       DAPHKZ010000070        21546 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.070, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000070 DAPHKZ010000000
VERSION     DAPHKZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21546
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.070"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            48..1562
                     /gene="caiT"
                     /locus_tag="RH288_002831"
     CDS             48..1562
                     /gene="caiT"
                     /locus_tag="RH288_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter"
                     /protein_id="HDV4031872.1"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNIWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     gene            1593..2735
                     /gene="caiA"
                     /locus_tag="RH288_002832"
     CDS             1593..2735
                     /gene="caiA"
                     /locus_tag="RH288_002832"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HDV4031873.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            2864..4081
                     /gene="caiB"
                     /locus_tag="RH288_002833"
     CDS             2864..4081
                     /gene="caiB"
                     /locus_tag="RH288_002833"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HDV4031874.1"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKARETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLATHTIAEVKERFAELNIACTKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     gene            4155..5708
                     /gene="caiC"
                     /locus_tag="RH288_002834"
     CDS             4155..5708
                     /gene="caiC"
                     /locus_tag="RH288_002834"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HDV4031875.1"
                     /translation="MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELN
                     QEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESA
                     WILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQ
                     PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYL
                     TVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATVTECIPMMIRTL
                     MVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRAGFCYEAEIRDDHNCPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAK
                     VLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIV
                     VVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCS
                     GKIIRKNLK"
     gene            5817..6602
                     /gene="caiD"
                     /locus_tag="RH288_002835"
     CDS             5817..6602
                     /gene="caiD"
                     /locus_tag="RH288_002835"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HDV4031876.1"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR"
     gene            6608..7198
                     /gene="caiE"
                     /locus_tag="RH288_002836"
     CDS             6608..7198
                     /gene="caiE"
                     /locus_tag="RH288_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HDV4031877.1"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFSGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRYHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     gene            complement(7407..7802)
                     /gene="caiF"
                     /locus_tag="RH288_002837"
     CDS             complement(7407..7802)
                     /gene="caiF"
                     /locus_tag="RH288_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414576.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HDV4031878.1"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     gene            complement(8064..11285)
                     /gene="carB"
                     /locus_tag="RH288_002838"
     CDS             complement(8064..11285)
                     /gene="carB"
                     /locus_tag="RH288_002838"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDV4031879.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAA
                     DVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGADRIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     DRLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     gene            complement(11303..12451)
                     /gene="carA"
                     /locus_tag="RH288_002839"
     CDS             complement(11303..12451)
                     /gene="carA"
                     /locus_tag="RH288_002839"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDV4031880.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEAILPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK"
     gene            complement(12907..13728)
                     /gene="dapB"
                     /locus_tag="RH288_002840"
     CDS             complement(12907..13728)
                     /gene="dapB"
                     /locus_tag="RH288_002840"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDV4031881.1"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTSERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNSL"
     gene            complement(13895..14809)
                     /gene="rihC"
                     /locus_tag="RH288_002841"
                     /pseudo
     CDS             complement(13895..14809)
                     /gene="rihC"
                     /locus_tag="RH288_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705986.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
     gene            complement(14875..15825)
                     /gene="ispH"
                     /locus_tag="RH288_002842"
                     /gene_synonym="lytB"
     CDS             complement(14875..15825)
                     /gene="ispH"
                     /locus_tag="RH288_002842"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDV4031882.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     gene            complement(15827..16276)
                     /gene="fkpB"
                     /locus_tag="RH288_002843"
     CDS             complement(15827..16276)
                     /gene="fkpB"
                     /locus_tag="RH288_002843"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDV4031883.1"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     gene            complement(16401..16895)
                     /gene="lspA"
                     /locus_tag="RH288_002844"
     CDS             complement(16401..16895)
                     /gene="lspA"
                     /locus_tag="RH288_002844"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDV4031884.1"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     gene            complement(16895..19711)
                     /gene="ileS"
                     /locus_tag="RH288_002845"
     CDS             complement(16895..19711)
                     /gene="ileS"
                     /locus_tag="RH288_002845"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDV4031885.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTRDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     gene            complement(19754..20695)
                     /gene="ribF"
                     /locus_tag="RH288_002846"
     CDS             complement(19754..20695)
                     /gene="ribF"
                     /locus_tag="RH288_002846"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDV4031886.1"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     gene            complement(20703..20921)
                     /locus_tag="RH288_002847"
     CDS             complement(20703..20921)
                     /locus_tag="RH288_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 family protein"
                     /protein_id="HDV4031887.1"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSAIKIAAGGQFLPVICAMAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     gene            21024..21287
                     /gene="rpsT"
                     /locus_tag="RH288_002848"
     CDS             21024..21287
                     /gene="rpsT"
                     /locus_tag="RH288_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDV4031888.1"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
BASE COUNT         5094 a         5802 c         5586 g         5064 t
ORIGIN      
        1 aaacgggaac gcaaaataaa tattcgtttt cacagtggaa ttaactcatg aagaatgaaa
       61 agagaaaaac gggaatagaa ccgaaggttt tctttccgcc gttaataatc gtcggcatac
      121 tttgttggct tacagtcaga gatctggatg cagcgaatgt cgttattaat gctgtattca
      181 gttacgtcac caatatatgg ggatgggcat ttgaatggta tatggtggtg atgcttttcg
      241 gttggttctg gctggtgttt ggcccgtatg ccaaaaagcg tttaggtaac gaaccgccag
      301 aatttagcac cgccagttgg atctttatga tgttcgcctc ctgtacgtct gctgccgtac
      361 tgttctgggg atcgattgag atctactact acatctccac cccgccgttt ggcttagaac
      421 cgaactcgac aggggcgaaa gagttggggc tggcttacag cttgttccac tggggacctc
      481 tgccgtgggc cacttacagc ttcctttcag tcgccttcgc ttacttcttc tttgtccgca
      541 aaatggaagt gattcgcccc agctcgacac tggtgccgct ggtaggtgaa aaacacgcca
      601 aagggttgtt cggcactatc gtcgacaact tctatctcgt cgccttgatc ttcgcgatgg
      661 gtaccagtct gggccttgcc acgccgctgg tgaccgagtg tatgcaatgg ttgtttggca
      721 ttccgcatac cctgcaactg gacgctatca tcattacctg ctggattatc ctcaacgcca
      781 tttgcgtcgc ttgcggtctg caaaaagggg tacgtatcgc cagtgacgtg cgtagttacc
      841 tgagcttcct gatgctgggt tgggtgttca ttgtcagcgg tgccagcttc atcatgaact
      901 acttcaccga ttcggtgggg atgttgctga tgtatctgcc gcgcatgttg ttctataccg
      961 atcccatcgc taaaggcggc ttcccgcagg gctggaccgt gttctactgg gcatggtggg
     1021 tgatttatgc tatccagatg agtatcttcc tcgcccgcat ctcccgtggt cgtactgtgc
     1081 gtgaactgtg cttcggcatg gtgctggggc tgacagcgtc aacctggatc ctgtggactg
     1141 tactcggtag taacactctg ctgttgatag ataaaaacat catcaacatt ccaaatctga
     1201 tcgaacagta cggtgtggcg cgcgccatca ttgaaacctg ggccgctctg ccactcagca
     1261 ccgccaccat gtggggcttc ttcatcctct gctttattgc caccgttacg ctggttaacg
     1321 cctgctctta taccctggcg atgtccactt gccgcgaagt acgcgatggt gaagaaccac
     1381 cgctgctggt gcgtatcggc tggtcaattc tggttggcat tatcggtatt gttctgctgg
     1441 cgctcggcgg cctgaaaccg attcaaaccg ccattatcgc cggaggatgc ccgctgttct
     1501 tcgtcaacat tatggtgacg ctctccttta ttaaagacgc gaaacagaac tggaaagatt
     1561 aattaacccc caaaatatca agaggttgaa agatggattt taatttaaat gatgagcagg
     1621 aactgtttgt cgccggtatc cgcgaactga tggccagcga aaactgggag gcctattttg
     1681 ccgagtgcga ccgtgacagc gtctacccgg aacgttttgt caaagcactg gcggatatgg
     1741 gtatcgacag tctgctgatc cctgaagagc acggtggtct ggacgcgggg tttgttactc
     1801 tcgccgccgt gtggatggag ctgggacgtc tgggggcacc aacctatgta ctgtaccagt
     1861 tgccgggcgg gttcaatacc ttcctgcgcg aaggcacaca agagcagatc gacaagatta
     1921 tggctttccg cggcaccggt aagcagatgt ggaactcagc gattaccgaa ccgggcgcgg
     1981 gctccgacgt gggtagcctg aaaacgactt atacccgtag aaatggtaag atttatctta
     2041 atggtagtaa gtgttttatt accagtagcg cctacacccc gtacatcgtg gtgatggcgc
     2101 gcgacggggc ttctccggac aaacctgtct acaccgaatg gtttgttgat atgagcaaac
     2161 cgggcatcaa agtgaccaaa cttgagaagc tcggtctgcg tatggatagc tgctgtgaaa
     2221 tcacctttga cgatgtggaa ctggacgaga aagacatgtt cggtcgggaa ggtaacggct
     2281 ttaaccgcgt caaagaagag ttcgaccatg aacgtttcct ggtagccctg accaactacg
     2341 gtacggcgat gtgcgccttt gaagatgcgg cgcgctacgc caaccagcgc gtgcagtttg
     2401 gcgaggctat tggtcgtttc cagttgattc aggaaaaatt cgcccacatg gcgatcaaat
     2461 taaactccat gaaaaacatg ctgtatgaag cagcgtggaa agcagacaac ggcaccatca
     2521 cctctggcga tgcagcgatg tgcaaatact tctgcgccaa tgcggcattt gaagtggtgg
     2581 atagcgcaat gcaggtgctg ggcggtgtcg ggattgcggg caaccaccgc atcagccgct
     2641 tctggcgtga cctgcgtgta gaccgcgttt ccggaggatc tgacgaaatg cagatcctga
     2701 cgctgggtcg tgcggtgctg aagcaatacc gctaagtccg tgcgctgcct gatgcgacgc
     2761 tgacgcgtct tatcaggcct acgggagcac gaatgtaggc cggataaggc gtttacgccg
     2821 catccggcag tcatgcgcta cataaatttt tcaggagcaa ataatggatc atctacccat
     2881 gccgaaattc gggccgttgg ccggattgcg cgttgtcttc tccggtatcg aaatcgccgg
     2941 accgtttgcc gggcaaatgt tcgcagaatg gggcgcggaa gttatctgga tcgagaacgt
     3001 cgcctgggcc gacaccattc gcgttcaacc gaactacccg caactctccc gccgcaattt
     3061 gcacgcgctg tcgttaaata ttttcaaaga tgaaggccgc gaagcgtttc tgaaattaat
     3121 ggaaaccacc gatatcttca tcgaagccag taaaggtccg gcctttgccc gtcgtggcat
     3181 taccgatgaa gtactgtggc agcacaaccc gaaactggtt atcgctcacc tgtccggttt
     3241 tggtcagtac ggcaccgagg agtacaccaa tcttccggcc tataacacca tcgcccaggc
     3301 cttcagtggt tacctgattc agaacggtga tgttgaccag ccaatgcctg ccttcccgta
     3361 taccgccgat tacttttctg gcctgaccgc caccacggcg gcgctggcag cactgcataa
     3421 agcgcgtgaa accggtaaag gcgaaagtat cgacatcgcc atgtatgaag tgatgctgcg
     3481 tatgggccag tacttcatga tggattactt caacggcggc gaaatgtgcc cgcgcatgag
     3541 caaaggtaaa gatccctact acgccggttg cggtctgtat aaatgtgccg acggctacat
     3601 cgtgatggaa ctggtgggca ttacccaaat tgaagagtgc tttaaagata ttggcctcgc
     3661 acatctgctt ggcacgccag aaatcccgga aggcactcag cttatccacc gtatcgaatg
     3721 cccttacggc ccactggttg aagagaaact cgatgcctgg ctggcgacac ataccatcgc
     3781 ggaagtaaaa gaacgctttg ctgaactgaa tatcgcctgc accaaagtgc tgaccgtacc
     3841 ggaactggaa agcaatccac agtatgtggc tcgcgaatca atcactcagt ggcaaacgat
     3901 ggatggtcgc acctgcaaag ggccgaacat catgccgaaa ttcaaaaata accccggaca
     3961 aatctggcgc ggaatgccct cacatggcat ggacacggct gccattttga aaaatatcgg
     4021 ctacagcgaa aacgacattc aggagttggt cagcaaaggt ctggccaaag ttgaggacta
     4081 aacgcgtggc gtcagtcggc ttgcctgact agcgcccgcc caataacaaa cgaacaaaaa
     4141 tggatagagg tgcaatggat atcattggcg gacaacatct acgtcaaatg tgggacgatc
     4201 ttgcggacgt ttacggtcat aaaacggcgc tgatttgtga atccagcggc ggagtcgtta
     4261 accggtatag ttatcttgag ttaaatcagg agattaaccg cacggcaaac ctgttttata
     4321 cgctggggat tcgcaaaggc gacaaggttg cactacatct cgacaactgc ccggaattta
     4381 tcttttgctg gttcgggctg gcaaaaattg gcgcgattat ggtgccgatt aacgcccgcc
     4441 tgttacgcga ggaaagcgcg tggatcctgc aaaatagcca ggcgtgcctg ctggtaacca
     4501 gtgcgcaatt ctatcctatg tatcaacaga ttcagcagga agatgccact caattgcggc
     4561 acatttgcct gacagatgtg gcacttcccg ctgatgatgg cgtgagttcg tttactcaac
     4621 tgaaaaatca acaacctgcc accttgtgct atgcaccgcc gctatcgact gacgatacgg
     4681 cggaaattct cttcacctcc ggcaccacct cccgaccgaa aggtgtggtg attacccatt
     4741 acaacctgcg cttcgctgga tattactccg cctggcagtg tgcactgcgt gacgatgacg
     4801 tctacctgac ggtaatgcct gcgtttcata tcgattgcca gtgtactgcg gcgatggcgg
     4861 cgttttctgc cggggccacc tttgtgctgg tcgagaaata cagcgcccgc gccttctggg
     4921 gacaggtaca gaagtaccgc gccaccgtta ccgaatgtat tccgatgatg atccgtacct
     4981 tgatggtgca gccgccttca gcgaacgatc ggcaacaccg cctgcgggaa gtgatgtttt
     5041 atctcaactt gtcggagcag gaaaaagatg cgttttgtga acgcttcggc gttcgcttgc
     5101 tgacgtctta tgggatgacg gaaaccattg tgggcattat cggcgatcgc cctggcgata
     5161 aacgacgctg gccgtcgatt ggtcgagcgg ggttttgcta cgaagcggag atccgcgacg
     5221 atcacaattg cccgctcccg gcaggtgaga tcggtgaaat ctgtattaaa ggcgtaccag
     5281 ggaaaaccat cttcaaagag tattttctca acccgaaagc cactgcgaaa gtgctggaag
     5341 ctgatggctg gctgcatacc ggcgataccg gataccgcga cgaagaaggc tttttttatt
     5401 tcgtcgatcg ccgctgcaat atgatcaaac gcggtggcga gaatgtctcc tgcgtggagc
     5461 tggaaaatat catcgccacc catccgaaaa ttcaggacat cgtggttgtg ggtattaaag
     5521 attcgattcg cgatgaagcc atcaaagcat ttgtggtgct gaatgaaggt gaaacattga
     5581 gcgaagagga attttttcgc ttctgcgaac aaaatatggc gaaatttaaa gtgccctctt
     5641 atctggagat cagaaaagat ctgccacgta attgctcggg gaaaataatt agaaagaatc
     5701 tgaaataaat gaaacggcag ggaactaccc tgccagctaa taatcacgct ctaaaacaat
     5761 atgcattttt tgcaggaatg ttgtcgtccc tgaaaaagca aaaatggaga aaaggaatga
     5821 gtgaatcatt acatctgacc cgcaatggat caattctgga aattaccctt gatcgcccaa
     5881 aagcgaatgc tattgatgca aaaaccagct ttgaaatggg cgaagtattt ctaaatttcc
     5941 gtgacgatcc gcaattacgt gtcgccatta ttaccggtgc cggagagaaa ttcttttccg
     6001 cgggctggga tttaaaagcg gcagcagaag gcgaagcacc ggatgctgac tttggcccgg
     6061 gtggttttgc gggattaacc gaaattttca atctcgacaa accagttatc gcagctgtga
     6121 acggctacgc ctttggcggc ggtttcgaac tggcgctggc ggcagatttt attgtttgtg
     6181 ccgataacgc cagcttcgcc ctgccggaag ccaaactggg catcgttcct gacagcggcg
     6241 gtgtgctgcg tctgccgaag atcctgccgc ctgccatcgt caatgaaatg gtgatgaccg
     6301 gcagacgaat gggcgcagaa gaggcgctgc gttgggggat agtcaaccgc gtggttagcc
     6361 aggcggaact gatggataac gcccgcgaac tggcgcagca gctggttaac agcgctccgc
     6421 tggcgattgc ggcgctgaaa gagatctacc gcaccaccag cgaaatgccg gtagaagaag
     6481 cgtatcgcta tattcgcagc ggcgtgttga aacactatcc gtcggttctg cattcggagg
     6541 atgccattga agggccgctg gcgtttgccg agaagcgcga tccggtgtgg aaaggacgtt
     6601 aacaaccgtg agctattacg cctttgaggg gttaattccg gtggttcacc cgacggcgtt
     6661 tgtccatccc agtgccgtct tgattggcga tgtgattgtg ggagccggtg tctacatcgg
     6721 cccactcgcc tcactgcgtg gtgactacgg gcggttgatc gtgcaagcgg gagccaatat
     6781 tcaggatggc tgcattatgc atggctactg cgacactgac accattgttg gggaaaacgg
     6841 ccatatcggg cacggagcga tcctgcatgg ttgtgtgatt ggtcgcgatg cattggtcgg
     6901 gatgaacagc gtgattatgg atggcgcggt cattggcgaa gagagcattg ttgccgccat
     6961 gagctttgtc aaagcgggct ttagcggcga gaaacgccag ttgttgatgg gtacgccagc
     7021 ccgcgctgta cgcagtgtta gtgacgacga gttacactgg aaacggttga ataccaaaga
     7081 gtatcaggat cttgtcgggc gctatcatgc atcgttacat gaaacgcagc cgttgaggca
     7141 aatggaggaa aatcgccccc gtttgcaggg gacaacggat gtgacgccta aacggtgatc
     7201 ttgccggatg cggcgtaaac gccttatcca actctgctgg agagcaaccg taggccggat
     7261 aagatgcgcc agcatcgcat ccggcgatag ctgtcggatg cggcataaac gccttatcca
     7321 acccggctgg agagcaaccg taagccggat aagatgcgcc agcatcgcat ccggcgacca
     7381 ggtcgcacgg tatcatcgaa atgacattaa cgacgcatac tctttgacaa catcatctgc
     7441 cacttctgct cgcggttaag ttccgtgagc ggaacggcag gaatacgcgg tgtctttctt
     7501 acgccgacta atttttcccg actgttattg cgcaggcgcg cgtaaatttg ttcatcgata
     7561 tcgaccactt taaccagtcg ctgacactgg catccccgcc cttccagctt attagggatc
     7621 atcttaactt cgcagcttat ttctgtgact tccgacagaa tataagtcag ggtattaacc
     7681 gccttgctgt gttcaatatc gaaatgaata gagatctctc ttgctatcac ccaccgattt
     7741 tcagccatca tccattcggc gattaacaag tagagtggtt tttcaacata tccttcacac
     7801 atacgaactc cagtttcaca aattaaaagt ctggctatga ctcgttttga agcaattaaa
     7861 caaggccata ttaaaattgt ggatatatcg atagtatgca acttcaccgt cgataagtgt
     7921 gagctaaatc ctgcttatgt catcaaaaat atcgattccc caaaagattt acttaatggg
     7981 caaaaaaaaa cggtcctcat cagagaaccg tattagttat tcgatcaaat tagcggatga
     8041 aaaatatctg ccatgacacg ctattatttg atctgtgcgt gcatttcctg caccgaaatt
     8101 actttttcag tcgcatcggc attcagcgcc atcgcggtgg caaagccgcc gttcagggtg
     8161 gtgtcgtaat gcactttata ttgcagcgca ctgcgacgaa tcacgcggga gtcttcaatc
     8221 gcacgacggc ctgaggtggt gttgatgatg taggtatatt cgccattctt gatacggtcc
     8281 tgaatgtgcg gacggccttc atgcaccttg tttaccagac gcgggttgat acctgcttcg
     8341 cccagcacaa tcgccgtgcc gtgggtcgca tccagctcga agccctgttt cagcagtttt
     8401 gccgccaggt ccaccacgcg ttctttatcg ccttcgcgca cggaaagcag cgcacgaccg
     8461 tgtttcttca tggtggagtt gctgcccagc tgcgctttgg caaacgcttc agcgaaggtg
     8521 cggcccacgc ccatgacttc cccggtagag cgcatttctg gccctaacag cgggtcaacg
     8581 cccgggaatt tattgaacgg cagcaccact tctttcaccg agtagtacgg cgggataact
     8641 tctttggtta cgccctgctc agccagcgat ttgccagcca tcacgcgcgc cgccactttt
     8701 gccagcggta cgccggtggc tttggagacg aacggaacgg tacgcgccgc acgcgggtta
     8761 acttcaatca ggtagacttc gttgtttttc accgcaaact gcacgttcat caggccgcgc
     8821 acctgcaatt cgaaggccag tttctgcacc tgctggcgca tcacatcctg aatttcctga
     8881 cttaaagtgt aggctggcag cgaacatgcg gagtcaccgg agtgcacgcc cgcctgctca
     8941 atatgctcca tgatgccgcc aatcagcacc atttcgccgt cgcagatggc gtccacatcc
     9001 acttctaccg cgtcatcgag gaagtggtcc agcaacactg gcgcatcgtt agacacgctg
     9061 accgccgtct ggaagtagcg acgcaggtct gcttcgtcat agacgatttc catcgcccga
     9121 ccgccgagaa cgtaagacgg acgtaccacc agcgggtagc caatctcttt cgccttctct
     9181 accgccattt cgatagcggt aacggtggcg ttcgccggtt gcttcagttt caggcggtca
     9241 accgcgtgct ggaagcgttc acggtcttcc gcacggtcga tagcatccgg gctggtgccg
     9301 ataaccggta cgccagcggc ttccagtgca cgcgccagtt tcagcggggt ctgaccgccg
     9361 tactgaacga taacgccttt cggcttctca atacgcacga tttccagcac atcttccagg
     9421 gttaccggct cgaagtagag gcggtcggaa gtgtcgtagt cggtggagac ggtttccggg
     9481 ttacagttaa ccataatggt ttcgtaaccg tcttcgcgca gcgccagcga ggcgtgtaca
     9541 cagcagtagt cgaattcgat accctgaccg atacggttcg ggccgccgcc gagaaccatg
     9601 attttttcac ggtcggtaga cggattcgct tcgcactctt cttcataagt ggagtacatg
     9661 taagcggtgt cggtggcgaa ctctgccgca caggtatcca cgcgcttata aaccgggtgc
     9721 aggtcatact ggtcgcgcag cttgcggatt tccgcttcgc gcacgcccgc cagttttgcc
     9781 agacgcgcat cggcaaagcc tttgcgtttc agctggcgca ggaattcagc gttcaggcca
     9841 gtgatgccca cttccgctac tttctcttcc agacgcacca gttcttcaat ctgtaccagg
     9901 aaccagcggt caatattggt caggttgaag acgccgtcca cagacaggcc cgcacggaac
     9961 gcatcggcga tgtaccagat acgatctgcg cctgcgtctt tcagttcgcg acggattttg
    10021 gttaacgctt ccgggtcatc caggctcact ttcgggtcga atccagtcgc accgacttcc
    10081 aggccgcgca gcgctttttg cagggattcc tgctgcgtgc gaccaatcgc catcacttcg
    10141 ccaaccgatt tcatctgagt ggtcagacgg tcgttagcac cggcgaattt ttcgaagttg
    10201 aagcgaggaa ttttagtaac cacatagtcg atggacggct cgaaggaggc cggagtacgt
    10261 ccgccagtga tgtcgttcat cagttcgtcg agggtgtaac ccaccgccag tttcgccgcc
    10321 actttagcaa tcgggaaacc ggtcgctttc gacgccagcg ccgaagaacg ggacacgcgt
    10381 gggttcattt cgataacaat cagacgaccg tttttcgggt tcaccgcaaa ctgaacgttg
    10441 gaaccaccgg tttcaacgcc gatttcacgc agcaccgcca tcgaggcgtt acgcatgatt
    10501 tgatattctt tgtcggtcag cgtttgggct ggcgcgacag tgatggagtc accggtgtgg
    10561 atgcccatcg catcgaagtt ttcgatagag cagacgatga tgcagttgtc gtttttatca
    10621 cgcaccactt ccatctcgta ctctttccag ccgatcagcg actcatcaat cagcaactct
    10681 ttggtcggag agagatccag accgcgggcg caaatttctt caaactcttc acggttataa
    10741 gcgataccgc cgccgctacc gcccatggta aaggatgggc gaataatgca cgggaagccc
    10801 acgtcagcgg caaccgccag cgcttcttcc atcgtgtgtg cgataccgga acgcgcggtt
    10861 tccagaccaa ttttcttcat cgctacgtcg aaacgacggc ggtcttctgc tttatcaatc
    10921 gcatcggcag tggcaccaat catggtgaca ccgaactctt ccaacacgcc ctgacgttcc
    10981 agctccagcg cgcagttcag cgccgtctga ccgcccatcg ttggcagcac cgcgtccggg
    11041 cgctcttttt caataatctt gcgtacaact tcccagtgaa tcggctcgat gtaggttgca
    11101 tcagccattt ccgggtcggt catgatggtc gccgggttgg agttcaccag aatgacgcgg
    11161 taaccctctt cacgcagggc tttacacgct tgcgcgccag agtagtcaaa ctcacacgcc
    11221 tgaccgataa caatcgggcc cgcacccaga atcaggatac tttttatatc tgtacgtttt
    11281 ggcatggctc ttttactcct gattacttag cggttttacg gtactgctca attaactcga
    11341 taaagtggtc gaacaacggc gcggcgtcgt gtggaccagg gctggcttca gggtgcccct
    11401 ggaagctgaa tgccggttta tcggtgcgat gaatgccctg taacgtaccg tcgaacaggg
    11461 atttatgcgt gacacgcagg tttgcaggta atattgcttc gtccaccgca aaaccgtggt
    11521 tctgggcggt gatcattacc acgtttttct ccacatcttt aaccggatgg ttgccgccgt
    11581 ggtgaccaaa tttcattttg acagtcttcg caccgctcgc cagcgccagc agctgatgac
    11641 cgagacagat gccgaatacc ggaatatcgg tttcgaggaa tttctggatg gcggtaatgg
    11701 cgtaatcgca cggggccggg tcgccaggac cgttggagag gaagatgccg tctggattca
    11761 ttttcagcac atcttccgca gaagtttgcg ccggaacgat ggtcaggcga cagcctctat
    11821 ccaccagcat ccgcaggatg ttgcgcttgg caccaaaatc ataagccacg acgtggaacg
    11881 gcagctcgtc ttcttttttc gcttctggca ggccaccggt caacgtccag ctcccttgtg
    11941 tccagctata ggcttctgcg gtggtcactt cttttgccag atccatgcca ttcagacctg
    12001 ggaacgcgcg ggctttttct aacgccagcg ccgcatccgg gttatcgccc gcgataatgc
    12061 agccattctg tgcgcctttc tcgcgcagta aacgcgtcag cttacgggta tcgatatcgg
    12121 caatcgccac gatgttatgg cgtttcaggt aagaagagag gtcttcggta ttacggaagt
    12181 tgctggcaat cagcggcagg tcgcgaatca ccagaccttg tgcatgtacc tgagaagatt
    12241 cttcatcggc gtcattggtg ccgacattgc caatatgggg ataagtaaga gtaacgattt
    12301 gacgagaata ggaaggatca gtgaggattt cttgataacc ggtcattgaa gtattgaaaa
    12361 cgacttcccc aaccgccgaa cctgttgccc ctatggcccg accgtgaaac tgggttccgt
    12421 cttccagaac caatagcgct gacttaatca aaacaccctc cagagaatat tcactcactt
    12481 tatttgcata ttaattcaca atgatgacgt aaatcaatgc aaatctgctt accgacgaat
    12541 ttctggcaaa cggcggcatt ctggagatat gggcgctaaa agtcaactta atggcaggat
    12601 tttttatatt attttgtggc tcatgcatgt tttacaggca ttaagcggca aaaagatcat
    12661 ataacctgtt ctggaaaacg cttgcgcagc aagaagattg catgaaataa aagcgagtag
    12721 ggaaaagtgg accaaatggt caaaatttac attaaaacaa caaaaaccga agacaaaaca
    12781 tgtaattttt ggcacttata gacaatttaa aaacataaca ctaaaaataa aagggccaaa
    12841 aattaaagcc ctttacaatc aataaattaa atgtgttatt tttgcaccat aacaaatatt
    12901 ttgtggttac aaactattga gatcaagcac atctcgcata tcaaaaagac cactttcctt
    12961 accactcaac cacaaagccg atcttaccgc gccgttagca aatgtcatgc ggctggacgc
    13021 cttatgggtg atctccagac gctcgccaat atcggcaaac atcgcggtat gttcgccaac
    13081 gatgtcacct gcacgcacgg tggcaaaacc aatggtgcca ggcacacgtt cactggtgtg
    13141 gccttcacga ctgtagaccg cgcaatcttt cagatcttta tcaagggcgt gggcgatcgc
    13201 ctctcccatt gccagtgcgg tgcctgacgg cgcatcaact ttatgtctat gatgtgcttc
    13261 aataatttcg atatcggtgt agtcacccat cactttggct gctttctcca gcagcttaag
    13321 catgacgtta acgccaacgc taaaattggc ggcaaagaca atcgcaatat cggcggcggc
    13381 gtcacgaatc gcctgtttac cggcttcgtc aaaccccgta gtgccgatca ccatcccttt
    13441 gccatgctgg cgacaaaaag cgagatggtt cagcgtacct tccggacggg taaaatcgat
    13501 aaacacatca aaatcatctt ttatcgcatc aaggctgctt tgcacggtaa cgcctgtttt
    13561 ccctgcacca gccagctcac cggcgtcgct gcccagtaaa gaagatcctt cgcgctccag
    13621 cgcagcgccc agctgcacgc cttctaatgc cagcgccgcc tgaatcaact ggcggcccat
    13681 acgccccccg gctcccgcga tggcaacgcg gatgtttgca tcatgcatag ctattctctt
    13741 ttgttaattt gcatagaccg ttttcagagt aaccagcgca tcgctacgcc gccagccaaa
    13801 aacgctgata attagaaatt aatgataaac agggagggat atcagtgaaa ggcatgagtc
    13861 gatgaatgac tgcatgccga taacatgtga caggttacgg caccagagcc agcaaatcag
    13921 ccacccactg ttggaagcct tttacattca gatccaatgc cacctgtaca ttggctggtt
    13981 tgcccaggca accgtcgata tcaaccaccg tcgtgcctga ggtaaattcg ccttgagttt
    14041 ctaccgcgac aaaacacggc ttgagggtga ataagtccgg gcgcaccagc caggcgatgg
    14101 cgcagagatc gtgcattcgc agaccgcttt gcatactgcc gctacggtag tggctaaaca
    14161 gggcgtggag catttttccg gtgcgattca actccggtaa agtagcgaga tagtcagggg
    14221 ttaatattgc ctgattggtg acatccagac cgcacatgac aatttcgatg ccgctacgga
    14281 agacacaggc agccgcttct ggatcggcag cgatattaaa ctcggcattt ggtgtacagt
    14341 tgccgcgacc agcagaaccg cccatgatca ccagacggcg aatatgcggt ttgcattccg
    14401 ggcattgtga aagtaacagc gcaatattgg ttaacgggcc gatggctacc agggtaacag
    14461 gctctggtgc acgcatcagg gcatcccgaa tcgccagaaa cgccggtacc tcgagcggct
    14521 ttcggttgtg ctcaacaaag tcgtagccag ccattcccga tttgccgtgc acagatgccg
    14581 catcacgcgg tgcgcgtacc agcggcacag cggctcccta ggcgagcgga atctccgcat
    14641 tccagaaatg cagcagttgc aaggcattac gggtagtttt ctcaaccgag acattacccg
    14701 cgacggtggt catcagttgc aggtcgagtt cgggggcaaa aatcgcggcg gcaatggcga
    14761 cggcatcgtc aatgccgggg tcagtatcga ggaagatagg taaacgcatg ttttctccat
    14821 aaaaaatgcc ggtaacaaga ccggcatttt cgcataactt aggctgctaa tgacttaatc
    14881 gacttcacga atatcgacac gcagctcttt cggcacttcg aaaacaatgt tttcttcacg
    14941 gccttccagc ggaatggctt caccaccgcc cagctgctgc aaacgtgcca ccacattttg
    15001 caccagaata tccggagccg atgcgcccgc agtcacgccg acgcatttaa cctctttcac
    15061 ccactcttcc tggatatctt tcgcatcgtc aatcaaaaac gcgcgtttgc ccatacgctg
    15121 ggccagctcc gccagacggt tggagttgga ggagtttttc gaaccgacca ccaacacaac
    15181 ttccgcctgt tctgccaggg cgcgtaccgc ttcctgacgg ttagtcgtgg cgtagcagat
    15241 gtcatctttg cgcggaccga caattttcgg gaagcgttta cgcagcgcgt cgatcacatc
    15301 agacgtgtca tccaccgaca gcgtggtctg ggtcataaag gagagcttct cttcgttttt
    15361 gaccgtcagt ttccacacat cgtccggcga ttcgaccaga tacattcccc cttccgggtt
    15421 actgtactgg cccatcgtac cttccacttc cggatgcccg gcgtggccga tgagaatcga
    15481 ctcttcgcca cgacggctgg cgcgggcgac ttccatatgc actttggtca ccagcggaca
    15541 ggtggcatca aacaccgtca aatcgcggct ttttgcttcg ttacgtaccg cctgagaaac
    15601 accgtgtgcg gagaaaatca ggatcgcgcc gtccggtact tcgctaatct gctcaataaa
    15661 gatagcccca cgctcacgca agctatcgac cacatagcgg ttatgtacca cttcgtgacg
    15721 gacatatatc ggtgcgccgt aaatggccag cgcgttttca acaatgctga tagcgcggtc
    15781 taccccggca caaaaaccac gcgggttggc caacaggatc tgcatgttac gcctccagtg
    15841 ccggatcgat ttccagcact tcaatatcaa aatgaacggt ctgcccggcc agcggatggt
    15901 tgaaatcaac ggtaatggag tcgccgttaa tttcgcggat cacgccaggc atctcactgc
    15961 catccattgc ggtaaaaagc atgattgcgc caatttctgg ctcgcctgca tccataaatt
    16021 cacggcggga gaagtactga atcaggtccg gtgacggcac gccaaacgcc gcatctggct
    16081 ccaacgagaa ggtggtttta tcgcccactt tcagccccaa caggtgttgc tccagccctt
    16141 cagaaagaga agcatcaccc aggcggaaca gcgccggttt accgttgttg cgggtagact
    16201 cggcggtggt gccatcgtcg agttttagcg tgaagtgcac caggacggcg ctattgctct
    16261 gtacagattc agacatgcag gtttgctctt atatttgagg atttttgccg gatgcggcgt
    16321 aaacgcctta tccggcctac gatttcgcag caatctgtag gccggataag atgcgtcagc
    16381 atcgcatccg gcagggttta ttattgtttt ttcgctttag aaggtaaaaa cccttccagc
    16441 acgatcaacg ccgcaccgac acaaatggca gtatcggcaa ggttgaaggt ggcgaagtgc
    16501 cagtcgccga cgtagaagtc gatcatatcg acaacgaagc cgtgccacag gcggtcgaac
    16561 aggttgccca gcgcgccgcc aataatcagc gcataagcga tattgtttag cttctgcgtg
    16621 gccttcgagc gatacatcat cactgccagg atcacgctaa taccaatcgc aataccggca
    16681 aagaaccaac gctgccagcc gccgctatcg gcaaggaaac taaacgccgc gccatagtta
    16741 cgcgcataat gcagattaag cgacgggaac agcgggaccg tatcccccag agcaaagttc
    16801 tggaggatca ggtatttgct gcccagatcg ataatcagca cgactaccac cagccacagc
    16861 cagcgtagcc ctgttgaaca gatcgattga ctcatcaggc aaacttacgt ttttcaccgt
    16921 caccggcgac gttgctgaca cagcggccgc agatttctgc gtgttccgcc accttgccga
    16981 catcccgggt gtagtgccag cagcgtgggc acttctcacc ttcggcttta ctcaacgcga
    17041 ctttcagccc tttgagtact tcgctctgct gagcatcagc aggtgcgtcg ttatagtctg
    17101 caacggtagc gccggaggtc aacaggacaa atcgtaattc atcgcccagc gcggtcagtt
    17161 tcgccgccag ttccggttct gcatacaagg ttactgccgc ttccagcgag ccacccactt
    17221 tcttgtcggc acgcgcttgc tcaatgactt tgttcacttc gccacgcact ttcaacagct
    17281 cgtcccagaa cgcatcgttc atcgcttcac tgtctgccag gccaaacagg ccttcgtacc
    17341 actcaccggt gaagacgtat ttttcacgtt cgcccggcag gtagccccac acttcatcag
    17401 cggtgaagga gaggattggt gccatccagc gcaccagcgc ttctgcgatg tgatacagcg
    17461 cagtctggca gctacgacgc gccacactgt ccgctttggc ggtgtactga cggtctttga
    17521 tgatgtcgag gtagaaggaa cccatctcaa cggagcagaa gcgcatcaga cgctgtacca
    17581 cttcgtggaa atcgtatgct tcgtacgcgt tgaggatgtc ttcctgtgcc gctttcgcac
    17641 aacctacggc ccagcgatcc agtaccacca tctcttccgg tttcaccata tcttttgctg
    17701 gatcaaaacc gttcaggttt gccagcagga agcgcgcggt gttacggata cgacgatagc
    17761 tatcggcagc acgtttcagg atctcgtcag aaacggccat ttcaccggtg tagtcggttg
    17821 atgccaccca cagacgcaga atatccgcgc ccagtttgtt catcacatcc tgcggcgaaa
    17881 cggtattgcc gatggattta gacatcttgc gaccctgacc atccacggta aagccgtggg
    17941 tcagtacctg acgatacggc gctttgcctt tcatcgcggt ggagatcatt agggaagaca
    18001 tgaaccaacc acggtgctgg tcagaacctt ccagatacat gtccgctgcg tgaccggcaa
    18061 attccggacg cacgtcaaca acagaagagt gggtagatcc ggagtcaaac catacatcca
    18121 atgtgtccgg cactttcacg tactgatcag cttcatcgcc gaggatctct ttcgcatcaa
    18181 gatcccacca cgcctggatg ccgtcaactt caacgcgttt tgccacttct tccattagtt
    18241 cgagagtacg cggatgcagc tcttccgtgt ctttgtgcac gaacagtgac atcggtacgc
    18301 cccaggtgcg ctgacgggag atacaccagt caggacggtt agcaaccatc gactcgatac
    18361 gcgcctggcc ccagtccggg atccactgca cgcctttgat ctctttcagt gactgcgcac
    18421 gcagaccttt ctgatccatg ctgacgaacc actgcggcgt cgcgcggaag atgatcggcg
    18481 ttttgtgacg ccagcagcac ggatagctgt gctgcatttt ctcaacgtgc agcagcgcgc
    18541 ctttttcctg cagcagcgca acgacgatgt cgttcgcttt gaagacgttc acgccatcca
    18601 gcgtcggata agtgcccggc agataagtgc cgtccgggcc aaccgggtta gcggtttcca
    18661 agccgtattt ctgaccgatc acatagtcgt ccgggccgtg gccaggcgcg gtgtgaacgg
    18721 caccggtacc ggcatccagg gtaacgtgat cgccgaggat tgccggaacg tcgaagccca
    18781 taaacggatg ggtaaagcgc agcaactcaa gctccgcacc ttttaccgtg ccgagaatgg
    18841 tgtaatcggt cacgccgata cgctgcatta cgctttcaac cagatctttc gccagaatca
    18901 cggcctgacc gtcgatctgc accagcgcat agtcgaaatc aggtgcaata gagattgcgc
    18961 ggttcgcagg cagagtccac ggcgtagtgg tccagatcac cagcgagatt gggccgttaa
    19021 cgttgcttac ggcaaatttt gctttcagtg catcctgatc gaccgcctga aaagcaacgt
    19081 cgatggacgg agaagttttg tcgtaatact caacttccgc ttccgccagc gcagaacggc
    19141 agtcaacgca ccagtgtacc ggcttcgcgc ctttgtgcag gtgaccgttg ccgatgattt
    19201 tgcccagcgc gcggatgatg ttggcttcag ttttgaagtc catggtcagg tacgggtgcg
    19261 accagtcgcc cagcacgccc agacggataa agtctttgcg ttgaccgtca acctgggtcg
    19321 ccgcgtattc gcggcacttg gcgcggaact cggcggcggt gaatttctca cccggcttac
    19381 cgtattcttg ctctactttc agctcgatcg gcagaccgtg gcagtcccag ccaggcacat
    19441 acggcgagtc ataaccggaa agccctttgg acttcacgat aatgtctttc aaaatcttgt
    19501 taaccgagtg accaatatga atgctgccat tcgcataagg agggccatca tgcagaatga
    19561 aggttttttt gcctttttta gccgcacgga tgatgccgta cagatcatca tcagtccaac
    19621 gcgccagcat tcccggttcg cgcttggcga gatcgccacg catcgggaac cctgtttccg
    19681 gcaaattcag ggttgattta tagtcactca tcagattctc ggttccgtgt ttcggtttga
    19741 ttacataaca ggcttaagcc ggttttgtta gcccaaaaaa ttcgcgggcg gttaattcat
    19801 cacgcgcaat ctgcgctttc agttcgtcca gcgacgcaaa tcgctgctca ttgcgtattt
    19861 ttttacgcag cactacttgt atatggcgac cgtaaaggtc cattgcaaca tctaacaaat
    19921 gcacttccag ctgctggcga ataccggcaa ccgttgggcg tgttccgatg tttgccacgc
    19981 cgggtaacgg cttttcaccg aggcccagca cttctaccgc ataaacccct ttcaccgggg
    20041 aaacctgacg gcgtagcggt acattcgccg tcgggaaacc tatagtgcgc cctaattcat
    20101 caccgtggac tacacgcccg gagatggcaa acgggtgccc cagtaaactt tctgccagag
    20161 ccagattgtc atccgccagc gcctgacgca cagcggtgct gctaatacgc acgccacctt
    20221 cgcaaaaagt ttgcgtacta gtgatatcga agccgtattc catgccagct ttctgtaata
    20281 acaagaaatc gccttcacga ccagcgccaa agcggaaatc atcccctacg gcaagaaatt
    20341 ttacgcgcaa atgcttcacc agaagatcgc tgatgaaatt ttgcgcggtt aacgccgcga
    20401 aacgcctgtc gaaacgcacg cacagcacgt aatcaacgcc acactctgca aggtaacgca
    20461 gtttttcccg cagccgggtc agccgtgccg gggctttatc ggtagcaaac agttccagtg
    20521 gttgaggttc aaaaagcatc accatcaccg gtaagttgcg cttgcgccct tcttcctgca
    20581 agccctgtaa cagcgcgcga tgaccgcgat gcacgccgtc gaaattacca atagtcagca
    20641 cacacccttc ttgcggggcc tggctgagat tatgtatgcc gcgtatcagc ttcatgtctg
    20701 gctcaaaaca gtgaaaatcg tccgagtata ccttgtacag cggtcaaggt taaccggcga
    20761 ttgagtaccg aaatcagaaa gaagtggctt ttcattgcca tggcgcaaat cacgggaaga
    20821 aactgaccgc ctgctgcaat ttttatcgcg gaaaagctgt attcacaccc cgcaagctgg
    20881 tagaatcctg cgccatcact acgtaacgag tgccggcaca ttaacggcgc ttatttgcac
    20941 aaatccattg acaaaagaag gctaaaaggg catattcctc ggcctttgaa ttgtccatat
    21001 agaacacatt tgggagttgg accttggcta atatcaaatc agctaagaag cgcgccattc
    21061 agtctgaaaa ggctcgtaag cacaacgcaa gccgtcgctc tatgatgcgt actttcatca
    21121 agaaagtata cgcagctatc gaagctggcg acaaagctgc tgcacagaaa gcatttaacg
    21181 aaatgcaacc gatcgtggac cgtcaggctg ctaaaggtct gatccacaaa aacaaagctg
    21241 cacgtcataa ggctaacctg actgcacaga tcaacaaact ggcttaatcg ccaatttgct
    21301 gaagctttgt gaaaaagccc gcgcaagcgg gtttttttat gcctgctgct tttgtgatgc
    21361 gtgagagaac acactgccgg ttgccagata gtcaaaagtt gcaggttctt gcagacatgc
    21421 cgttgtacta tctgaactct tcgtggctta agaatcgtag aaccatcggc tgatacattc
    21481 tgaacaagaa tatctactca atctccagac cccctacaaa gaatgtggat attgtgatac
    21541 acattg
//
LOCUS       DAPHKZ010000071        21475 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.071, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000071 DAPHKZ010000000
VERSION     DAPHKZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21475
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.071"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            32..1003
                     /locus_tag="RH288_002849"
     CDS             32..1003
                     /locus_tag="RH288_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M28 family peptidase"
                     /protein_id="HDV4031889.1"
                     /translation="MKKIIFAFIILFVFLLPMIIFYQPWVNALPSTPRHASPEQLEKT
                     VRYLTQTVHPRSADNIDNLNRSAEYIKEVFVSSGARVTSQDVPITGGPYKNIVADYGP
                     ADGPLIIIGAHYDSASSYENDQLTYTPGADDNASGVAGLLELARLLHQQVPKTGVQLV
                     AYASEEPPFFRSDEMGSAVHAASLERPVKLMIALEMIGYYDSAPGSQNYPYPAMSWLY
                     PDRGDFIAVVGRIQDINAVRQVKAALLSSQDLSVYSMNTPGFIPGIDFSDHLNYWQHD
                     IPAIMITDTAFYRNKQYHLPGDTADRLNYQKMAQVVDGVITLLYNSK"
     gene            1106..1609
                     /locus_tag="RH288_002850"
     CDS             1106..1609
                     /locus_tag="RH288_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDV4031890.1"
                     /translation="MGMIGYFAEIDSEKINQLLESTEKPLMDNIHDTLSGLRRLDIDK
                     RWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLES
                     LDRNELRKQFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNH
                     ALTVIVG"
     gene            complement(1882..2598)
                     /locus_tag="RH288_002851"
     CDS             complement(1882..2598)
                     /locus_tag="RH288_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031891.1"
                     /translation="MEWLSEIRKLRKNVPVGIQVARRLLERTGGDVDEAIKLFHIDQI
                     NILTAKADVTHQEAENVLLATNYDIAEALRRIDEQRYTLTELILRKNKDAGDALNNIA
                     LAIEYEWDLKRKFWFGFADIQLLPPVLQTFMLVYEWHEYVGWEGMECGIFFESDHTHQ
                     QLQALGLLELAQKMVTARIRYDELKDKAENFHEITEDDIFKMLIIHCDQLAREVDSIL
                     LQFVKDNIDVFPCRHNRHEL"
     gene            2807..3229
                     /locus_tag="RH288_002852"
     CDS             2807..3229
                     /locus_tag="RH288_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031892.1"
                     /translation="MTPLERITQLVNINGDVNNPDTPRPLLSLEDFFIDNNIHGSICC
                     NVIPEQSPQAIYHHFLKIRERNNVSDVLVEITMFDDPDWPFSESILVITTASPEEVQS
                     WFVEEIAPDECWEGWSEDTEHGWVEVPVGMHPVTCWWD"
     gene            3288..4136
                     /locus_tag="RH288_002853"
     CDS             3288..4136
                     /locus_tag="RH288_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416778.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDV4031893.1"
                     /translation="MKLIPRSSDISPGIDGICPGPFPPNGFTVLTDAAYGNGDCFGLY
                     WPIGQEHKLPIVCETYHDEWRIVPAFSSIKKFEEWLEVNDDDPHENGISIEDQDFAAN
                     LFRVARKCLSTGRLDDALPLLQRATEQLPEVSEYWLALAIQYRRCKKTEAAAQAALNA
                     YLGNWAFGVPDNKVIHLLSQAADVPNFQDDPVIQCIKEQGLDLSFGGTKENNNYPLMQ
                     MCVDTYFAQRKPLQALTLLHNYAWIMSSETTAFQERYDFNIDEWRAKFRQLCLEYFGD
                     SRTQFT"
     gene            complement(4220..5677)
                     /gene="nuoN"
                     /locus_tag="RH288_002854"
     CDS             complement(4220..5677)
                     /gene="nuoN"
                     /locus_tag="RH288_002854"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HDV4031894.1"
                     /translation="MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNK
                     DEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM"
     gene            complement(5684..7213)
                     /gene="nuoM"
                     /locus_tag="RH288_002855"
     CDS             complement(5684..7213)
                     /gene="nuoM"
                     /locus_tag="RH288_002855"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HDV4031895.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSL
                     QLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAV
                     LCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSSG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFA
                     VATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTR
                     P"
     gene            complement(7377..9218)
                     /gene="nuoL"
                     /locus_tag="RH288_002856"
     CDS             complement(7377..9218)
                     /gene="nuoL"
                     /locus_tag="RH288_002856"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HDV4031896.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALV
                     TAFIGVDFFANGEQTYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMY
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKG
                     VTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLA
                     AWLWLGKRTLVTSIASSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     SMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(9215..9517)
                     /gene="nuoK"
                     /locus_tag="RH288_002857"
     CDS             complement(9215..9517)
                     /gene="nuoK"
                     /locus_tag="RH288_002857"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HDV4031897.1"
                     /translation="MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(9514..10068)
                     /gene="nuoJ"
                     /locus_tag="RH288_002858"
     CDS             complement(9514..10068)
                     /gene="nuoJ"
                     /locus_tag="RH288_002858"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HDV4031898.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAI
                     MLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRKDDSAKRKTEEHA"
     gene            complement(10080..10622)
                     /gene="nuoI"
                     /locus_tag="RH288_002859"
     CDS             complement(10080..10622)
                     /gene="nuoI"
                     /locus_tag="RH288_002859"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HDV4031899.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(10637..11614)
                     /gene="nuoH"
                     /locus_tag="RH288_002860"
     CDS             complement(10637..11614)
                     /gene="nuoH"
                     /locus_tag="RH288_002860"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HDV4031900.1"
                     /translation="MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVP
                     VSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ"
     gene            complement(11611..14337)
                     /gene="nuoG"
                     /locus_tag="RH288_002861"
     CDS             complement(11611..14337)
                     /gene="nuoG"
                     /locus_tag="RH288_002861"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HDV4031901.1"
                     /translation="MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE
                     ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSLE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVV
                     LENDLHRHASAIRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPE
                     LAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEG
                     NNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTS
                     VPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     RVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ"
     gene            complement(14390..15727)
                     /gene="nuoF"
                     /locus_tag="RH288_002862"
     CDS             complement(14390..15727)
                     /gene="nuoF"
                     /locus_tag="RH288_002862"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDV4031902.1"
                     /translation="MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVNQVKDAGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGAWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIN
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(15724..16224)
                     /gene="nuoE"
                     /locus_tag="RH288_002863"
     CDS             complement(15724..16224)
                     /gene="nuoE"
                     /locus_tag="RH288_002863"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HDV4031903.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHINGY
                     QGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHAHLTPEAIPE
                     LLERYK"
     gene            complement(16227..18029)
                     /gene="nuoC"
                     /locus_tag="RH288_002864"
     CDS             complement(16227..18029)
                     /gene="nuoC"
                     /locus_tag="RH288_002864"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HDV4031904.1"
                     /translation="MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHL
                     ISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
                     PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFL
                     NLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLA
                     SYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENF
                     DFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRVRTPSF
                     AHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(18123..18785)
                     /gene="nuoB"
                     /locus_tag="RH288_002865"
     CDS             complement(18123..18785)
                     /gene="nuoB"
                     /locus_tag="RH288_002865"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HDV4031905.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLND
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(18801..19244)
                     /gene="nuoA"
                     /locus_tag="RH288_002866"
     CDS             complement(18801..19244)
                     /gene="nuoA"
                     /locus_tag="RH288_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HDV4031906.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     SKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR"
     gene            complement(19875..20813)
                     /gene="lrhA"
                     /locus_tag="RH288_002867"
     CDS             complement(19875..20813)
                     /gene="lrhA"
                     /locus_tag="RH288_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HDV4031907.1"
                     /translation="MISANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPST
                     FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYV
                     ASTLPAVRAAVKAGLGVTARPVEMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNEL
                     AQVIYQAMESYHNPWQYSPMSAPEGDDSLLIERDIE"
BASE COUNT         5504 a         5731 c         5335 g         4905 t
ORIGIN      
        1 ttcaacaacg caacccatta ataatttgca tatgaaaaaa ataatctttg cttttattat
       61 attatttgtg tttttactcc ctatgattat tttttaccaa ccctgggtca atgcattacc
      121 gtcaacgccc cgacacgcaa gtcctgagca attagaaaaa acagttcgtt atcttacaca
      181 aactgtgcat ccacgtagtg ccgacaatat tgataatctg aataggtccg cagaatatat
      241 aaaagaggtc tttgtcagta gcggtgccag agttacctcg caggacgtcc ccattacggg
      301 tggcccctac aaaaacattg ttgctgatta tggtcctgcc gatggaccgc tgattattat
      361 tggtgcgcat tatgactctg ccagcagtta tgaaaacgat caattgacct atacgccggg
      421 cgcggatgat aacgccagcg gtgtggcagg attactcgaa ctggcacgtt tgttacatca
      481 gcaagtaccg aaaacaggcg tgcagctggt cgcctatgcg tcggaagaac cgcccttctt
      541 tcgtagcgat gaaatgggga gcgcggtgca tgcagcttcg cttgagcgtc cagtgaaatt
      601 aatgatagca ctggagatga ttggctatta cgactctgcg cctggaagcc agaattaccc
      661 ttacccggca atgtcctggc tttatcccga tcggggagac tttattgccg tggtcggcag
      721 aatacaggat atcaacgccg ttcgtcaggt aaaagcggca ttgttgtcat ctcaggattt
      781 atctgtttat tctatgaata ccccagggtt tattcccggt attgatttct ctgaccacct
      841 gaattattgg caacacgata ttcccgccat aatgattact gacaccgctt tttatcgtaa
      901 taaacaatac cacttgcccg gtgataccgc agacagattg aattatcaga aaatggctca
      961 ggtagtggat ggtgttataa ctttgttata caacagtaaa taataaaaat ttctcgaggc
     1021 gggtccagaa aaagcgacat gcacatttta ttttccctca tctgttttaa gatgcgaaac
     1081 atgaaattca acggaggaaa aataaatggg aatgattggc tattttgcag aaattgactc
     1141 agaaaagatt aaccaactgc ttgagtctac tgaaaaacct ttgatggata atatacatga
     1201 cacgctttca ggattacgcc gactggatat tgataaacgc tgggattttt tacactttgg
     1261 gctgacaggc acctctgctt ttgatcccgc gaagaatgat ccgctgagtc gtgccgtgct
     1321 tggtgaacac agcctcgaag atggcataga tggcttcctt ggattgacct ggaatcagga
     1381 gttagccgcg acaatcgacc gactggaatc actggatcga aatgaactgc gtaaacagtt
     1441 ttccattaag cgactcaatg aaatggagat ttatccggga gtgacctttt cagaagagtt
     1501 agaggggcaa ctctttgcct cgatcatgct tgatatggaa aagctgatta gcgcgtatcg
     1561 acgtatgctg cgacaaggga atcatgcgct gacggttatt gttgggtgat atagcttgat
     1621 gcctggggga gaaagaccca ttagttaaga tttacgccag gatcatcttg aaaaaatctt
     1681 taaccatggt ccggttttta tccccttgta taaatattac taaatgcttg cttagtcgca
     1741 ttgttaaatg caataccgta tattcggtat gtaacagcga tatcctctgt gctggcaacg
     1801 atctgtcatg cttgatgaaa acggaattga acctgtcatt accaggtaga taaaaagcct
     1861 gttcaatttt gggattattt tttataactc gtgtctgtta tggcgacacg ggaaaacatc
     1921 aatattgtcc ttcacaaatt gcagtaatat agaatcaacc tctcttgcaa gttggtcaca
     1981 atgtattata agcattttga atatgtcatc ctctgtaatc tcgtgaaaat tttcggcctt
     2041 gtcttttagc tcatcatatc ggattcttgc agtaaccatt ttttgggcga gttctaataa
     2101 ccccaaagct tgcaattgct ggtgagtatg atcactttca aaaaatatcc cacactccat
     2161 tccttcccaa ccaacatatt catgccattc ataaaccagc ataaatgttt gtaaaactgg
     2221 cggtaataat tggatatctg caaaaccaaa ccaaaactta cgcttgagat cccactcata
     2281 ttcaatcgcc aatgctatat tgtttaaggc atctccggca tccttatttt tacgcaaaat
     2341 caattccgtc agtgtatagc gttgttcatc aatacgccga agagcttctg caatatcata
     2401 gtttgtagcc aacaaaacat tctctgcttc ctgatgagtg acgtctgctt ttgccgtcaa
     2461 tatattgatt tggtcaatat gaaacaactt gatggcttca tcaacatcac cgccagtcct
     2521 ctctaacaaa cgtctggcaa cctggatacc gacaggtacg ttcttccgaa gtttacgaat
     2581 ttcacttaac cattccatgt caaacccctt taaatattta tgatattaaa tataacaacg
     2641 tctggataac gacccggcct gactgaatat ctcacgtttt cctgcttaac attcatgtta
     2701 tgatgctctt gaaactaata atacgtatgg aattgtcact atttatctgc taatgaattc
     2761 aaacaatgtc attcgtttga tgaatatatt atttcaggga ataattatga cacctttaga
     2821 acgcattacc caacttgtta atatcaatgg tgatgttaat aatcctgata ctcctcgtcc
     2881 attgttatct cttgaggatt tttttattga caataatatc catggttcaa tatgttgcaa
     2941 tgtgattcca gaacaatctc cgcaagctat ctatcaccat tttctgaaaa tacgtgagcg
     3001 taacaatgtt agtgatgttt tggtagaaat tacgatgttc gatgacccag actggccctt
     3061 tagtgaaagt attttagtta tcaccactgc ttcaccagaa gaagttcaga gctggtttgt
     3121 agaagaaatt gcccctgatg agtgctggga aggatggtca gaagatacgg agcatggatg
     3181 ggttgaagtc cctgtgggta tgcatccggt tacttgttgg tgggattaaa acatttatat
     3241 aaacagataa gcggatgttt acataaattt ttatgtgaag gaacatgatg aaacttattc
     3301 ctcgcagtag tgatatttca cctggcattg atggaatttg cccggggcct tttcctccga
     3361 acggatttac cgtacttaca gatgcagcat atggtaacgg agactgtttc ggtttgtact
     3421 ggcctattgg tcaggagcat aaactaccta tagtgtgcga aacgtaccat gacgaatggc
     3481 gaatcgtacc tgccttttcc agcattaaga agttcgaaga atggctggaa gtgaatgatg
     3541 atgatcccca tgaaaatggc atcagcatcg aagatcaaga ctttgcagca aatctcttcc
     3601 gtgttgctcg gaaatgtctt tcaacgggaa ggcttgatga cgcactgcca ctgttacagc
     3661 gagcaacaga acaattgcct gaagtcagcg aatattggtt agcactggca atccagtatc
     3721 gccgatgtaa aaaaacagaa gctgcagcac aggctgcgct taatgcttat cttggcaatt
     3781 gggcatttgg tgttcctgac aataaagtca ttcatttgct gtcacaggcc gcagatgtcc
     3841 cgaatttcca ggatgatcct gtgattcagt gcattaaaga acaaggatta gatcttagct
     3901 ttggaggaac aaaggaaaat aataattacc ccttgatgca gatgtgtgtt gatacttatt
     3961 ttgcgcagag aaaaccgctt caggcattaa ccctgttaca taattatgcc tggataatgt
     4021 ccagtgaaac gactgcattt caggaacgct atgattttaa tatcgatgaa tggcgggcaa
     4081 aattcaggca gttatgttta gagtattttg gcgatagtcg tacacagttc acttaacgct
     4141 ctgcgtctat ctactatccc ttctttttca gaaaaaccgc cgagcatgtc ggcggctttc
     4201 tgacttacaa agtaacagat tacatcagcg gcattgccaa acgcacaatg ctaatcagcg
     4261 gttgtggcca tacacccagc accagtacca acagtgcaga gatcagcaca acgataccgc
     4321 ccgcgctgta ctgccagttt gatggtgcat cgcgacccgg ttgttccggg gcgtgaagat
     4381 acaggctcac cgccacgcgc aggtagtagt agaggccgat tgccgaaccg acaaccacgg
     4441 cacccaccag ccaccacaag tgtgcctgga caccgaccgc cagcacgtag aacttaccga
     4501 taaagcccag cgtcatcggg ataccggcca gagacagcat catcaccgtc atcactgccg
     4561 cgaggatcgg acgatgccag aacagaccgc ggtaagagaa cagggaatca gcatccgggc
     4621 cacgatacgg gctggacatc aggctgacca cgccgaacgc gccgaggctg ctgaacagat
     4681 aaccggccag gtaaacccct accgcttcca tcgacatctc gccggtttgc agcgcaatca
     4741 gcgctaccag cagatagccg aggtgagaga tagatgagta accgagcaga cgtttgatat
     4801 tggtctggct cagcgccatc aggttaccga agatgatgga ggcaaaggcg ataatcgcca
     4861 gcaccacgcg aatcgcttcg ctgtcaccca ccggtgcgta gaggaacaga cgcatcacca
     4921 caccgaagat agcgattttg ctcgccgtcg ccaggaaagt ggaaaccggc gcaggcgcgc
     4981 cctggtatac gtctggcgtc cacaggtgga acggcaccag agagagtttg aagccgaggc
     5041 caacaatcat caggccgaaa cctgccagca acagcggctc gttgagcata ccgtcgccaa
     5101 ggtttttacc caacgcgaca aacgacaggt cgccagactg cgcatacacc agcgccatac
     5161 caaacagcag gaaagaagac gctgcggcag aaaggatggt gtatttgata ctggcttcca
     5221 gtgaacgttt ctggcggaaa gcgtaaccga ccaggccaaa cagcggcaaa gagatcagtt
     5281 cgataccgag gaacagagac gccagatggt tggcattcgc cagcaggatc ccgcccagcg
     5341 cggcaattaa caccaacagg tagaactcat ccttgttgtc gttatagcct tcaagccacg
     5401 ggtaggcgaa agtacaggtg gcgaggctcg ccaacaatac cagcccggtg taaagcatgg
     5461 cgaaaccatc aacgcgcatc agcggcgtaa cgtccatagc gcccgcctgg ccaacaaacc
     5521 agagcgaaac cagcgccgcg ttaagcccaa taaccgagag cgtagcgttg aggaaatgat
     5581 tgcgtcgcca cgcaatggag agcatcacaa ccaccaccgt caagccgacg atcagcaacg
     5641 gtagcagtgc gatcaggttt tgtggagtta ttgtcatggc gatttacggc cttgtagtag
     5701 taacggaatt aacaaaccac tgctggatat tgccaatcgc ggagtgcgag gtatccagaa
     5761 tcggctgcgg atagaagccc agcagtacca gcagcaccac cagcaacagg atcataaaca
     5821 gctcacgcag cgacatccct ggcagttcct ggctggcaat ctggcttttc gctttaccga
     5881 agtaagcgcg atgtaacatc gccagcgaat aaacagatgc aaagaccagc ccaaaggtag
     5941 agataacggt aatcaccggt acaacctgga agctgccgaa cagaatcata aattcgccga
     6001 cgaagttacc ggtgccaggc atcccaagcg ttgccaccgc aaagaacagc gacagtgctg
     6061 gcagccattt catcttgctc cacagaccgc ccatcatgcg catgtcgcgg gtatggatac
     6121 gttcataaag ctgaccacaa agaataaaca gacccgccgc cgacaaaccg tgcgcaatca
     6181 tctggattac cgcgccctgg taggccaact ggctgccggt gtagatagca atcagcacga
     6241 agcccatgtg ggaaaccgag gtgtaggcga tcagacgttt gatatcggtc tgggcgaagg
     6301 ccatccacgc accgtagaag atgccgataa cacccagcca catagcaatt ggcgcgaact
     6361 ctgccgacgc gttcgggaac agcggcaggg agaaacgcag caaaccgtaa gcggcagttt
     6421 tcagcaagat ccccgcgagg tcaacggaac cggcggtcgg agcctgggag tgcgcatccg
     6481 gcagccagcc atgcagcgga accaccggca ttttgactgc gaaggcgatg aagaagccca
     6541 gcattaacag gtattccaca ccactggaca ttggcgtatt cagcagctct tcatagttga
     6601 aggtccagac gccggtcgca ttgtagtgaa caaaaaccag cgccaggatg gcaatcaaca
     6661 tcaccaggcc actcgcctgg gtgtaaatga agaacttggt tgccgccgtg atacgcgttt
     6721 taccgtcaga ggctttatgc ccccacagtg cgatcaggaa gtacatcggc accagcatca
     6781 tttcccagaa gaagaagaac aggaacatgt cgatggcaag gaacacgccg ataacgccgc
     6841 ccaggatcca catcaggttg aggtggaaga agccctgata tttttcgatc tctttccacg
     6901 aacatagtac cgccagcaca ccgagcagac cggtcagcac gaccatcagc agcgacagcc
     6961 cgtcaatggc gagatgaata gagataccaa aacgcgggat ccacggcatg tcgaattcag
     7021 actgccactg cggaattccg gcggattgcg tcagtgaata accgccctgc aaccacagtt
     7081 gcagcgacag cgccagcgtc aatcccatgg tgatcagcgc gatccagcgt ggcaccttga
     7141 cgccaaagcg ttcggtctgc cagcacagga agccgccaat aaagggaatt aatattagcc
     7201 agggtagtaa catggcgatc tttattcctt gtaaaagtcc cgtcaggacc ggattttcaa
     7261 cgaattctca cgacagaaaa ttctcttcgg actgggggta gtgtcggatg caccgcgaag
     7321 gcggcttatc cgacctacgt tcttatatgc ccaggggcaa tcccacaatc cttaactcaa
     7381 cgcagtacca tcaacagtgc cagcaccacg accgcaccga tgctcatgga tgccacatac
     7441 cagcgcagat agccgttctc acttaacagc agacctttac ctgcaaagcg ggaaaggaca
     7501 gccgggatgt tcatcattga gttcagcgga tcgcgtttca gcaaccaggc aatacccagg
     7561 aacggcttga cgaacacttt gtcatacagc cagtcaaatc cccaggcgtt gtaccaccag
     7621 gtgcccagca gacggcccgg cgcactgctg gcgatggagg tcaccagagt acgtttaccc
     7681 agccacagcc aggctgccag cagaatgccg accaccgcga ccacgccaga ggtaatttcc
     7741 agggtcaaca tgctgccgtg cgccagttcc gtcgtttgcg gaagcacgcc ctgcagcggc
     7801 ggtacaatca gtgcgccaac gaaggtggaa aggatcagca gcacaatcag cggcaggctg
     7861 tgagttaccc ctttcacggc gtgagcgtga atttgttctt ttccgtggaa gacgatgaaa
     7921 atcatacgga aggtgtagag cgaggtcata aacgcaccga ccagacctgc caccatcaga
     7981 ttgatatgac cattcgccat cgcacccgcg aggatctcat ccttactgaa gaagcccgca
     8041 gtgaccagcg gtagtgccga cagtgctgcg ccgcccacca ggaagcagag ataaaccagc
     8101 ggaatagatt tacgcagacc gcccatcttg aagatgttct gttcgtgatg gcaggccaga
     8161 atgacggaac cggatgccag gaacagcagc gctttaaaga acgcgtgggt catcaagtgg
     8221 aaaatcgccg catcccatgc ctgcacgcca agcgcgagga acatgtagcc aatctggctc
     8281 atggtagagt aagcgagaac acgtttgatg tcggtctgta ccagcgcggc aaaaccggcc
     8341 agcagcagcg taaccgcccc gacaataccc accagatgca gaacttccgg cgtcatcagg
     8401 aacaggccgt gggtacgggc gatcaggtag acacccgcgg ttaccatggt tgcggcgtgg
     8461 atcagcgcgg agacaggcgt cgggcccgcc atcgcgtcgg caagccatgt ctgcaacggc
     8521 aactgcgcag atttaccgac cgcaccgccc agcagcatca gcgtcgccca catcagcatg
     8581 ttattgccgt cagcaaagtg cgctggtgcc agttccacca tttcgcggaa gttcagggtg
     8641 cccagttcgt tgtaaagaat gaacagtgcg aaagcgagga acacgtcacc cacacgggtc
     8701 acgacgaacg ctttcattgc cgctgcgcca ttcttcggat cggtgtaata gaacccgatc
     8761 agcagatagg agcacaggcc cacgccttcc cagccgaggt acatcagcag caggttgtcg
     8821 gcaagcacca gaaccaccat gctggcgatg aacaggttgg tgtaagcgaa gaagcgagag
     8881 tagccctctt caccgcgcat ataccaggag gcgtacatgt gaataaggaa acccacacca
     8941 gtgaccaccg agagcatggt cagcgacagg ccgtccagca ccaggttaaa accgatgtta
     9001 aagtcgccta ccgacatcca cgtccacagc ggctggctgt atgtctgctc gccgttagcg
     9061 aagaaatcaa cgccgataaa ggcggttacc agcgccgcca ggcccacaga gcctacgccg
     9121 acgatcgccg agacgttttc agaccagcgc ccacgggaga atgccagcag gacgaagcca
     9181 atcaatggca aaataatggt taaggcaagc atgttcatcc gcgcatctca cttactgaat
     9241 cgatgttcag gttctggcga cgacggtgaa gttgcagcag cagcgcaagg ccgatactcg
     9301 cttctgccgc cgcgaggctg atggcgagaa tgtacatcac ctgaccgtcg gtctggcccc
     9361 agtagcttcc ggcgaccacg aaggccagcg cggaggcgtt aatcatgatt tccagaccaa
     9421 tcaacataaa cagcagattg cgacggataa ccagaccggt taagccaaga acgaataaga
     9481 ttgccgcgag gatcagtcca tgttgtaagg ggatcatgcg tgctcctccg tttttctttt
     9541 cgcgctgtcg tctttacgat tgctcagcac ttcacccgca cgctcttcac gaccgacgtg
     9601 gaaggccaca accagacctg cgagcagcag catagaagcc agttccaccg ccagtacgta
     9661 aggcccgaac agcgtaatac ccactgcttt agcactgatt ggcgtaccgt cgataccctg
     9721 atcgttaaca ccgaggatgg cgtaaacaat caccaccagc atgatggccg acaaaattgc
     9781 cggaccaatc cacacctgcg gtttcagcca ctggcgttcc tgttcgattt ctgaaccgcc
     9841 caggttgagc atcatcacca cgaacacgaa cagcaccata atggcacccg cgtagacgat
     9901 aatttccagc gcaccggcga agtaagcgcc cagtgagaag aacaccccgg aaatcgccag
     9961 cagcgaaata atcaggtaca gcagtgcgtg taccggattg gtatgggtga tcactcgcaa
    10021 ggtcgcaagt atggctatca ggccacagat ataaaaagcg aactccattg cccctctcct
    10081 tacggtaaca ggctcttgac gtcgataggc ttggcttcgt tctctgcttc gcccttatct
    10141 ttgccgtcga ttgccatacc tgccatccgg tagaagttat attccgggta tttgcccgga
    10201 ccggagatca gcagatcctc tttctcgtaa accagatcct ggcgcttgta ttcccccatt
    10261 tcgaaatccg gggttaactg aatcgccgtg gtcggacagg cttcttcgca cagaccacag
    10321 aaaatgcagc gtgagaagtt gatgcggaaa aattccgggt accagcgacc gtctttggtt
    10381 tctgcttttt gcagcgagat acagccgacc gggcaggcta ccgcgcagag gttacaggct
    10441 acgcaacgct cttcgccgtc cgggtcgcgg gtcagaacga tacgaccacg ataacggggc
    10501 ggcagataga ccggctcttc cgggtacatt cgcgtttcgc gtttggcgaa cgcgtgcagg
    10561 ccgatcatcc agatactacg aacctgggtg ccgaaaccta ctaacaattc ttttaaggtc
    10621 atggtcttat tgccccttat tgcgcctgcc agagaatgac agccgccgtt accagcaagt
    10681 tgatcagcgt cagcggcagg cagattttcc agccgaagga cattacctgg tcataacgcg
    10741 gacgcggtaa cgacgcacga atcaaaatga acatcatcat aaagaacgcg gttttcagcg
    10801 cgaaccagat gaatggcggt aacaacgggc cttgccagcc accgaagaac agcgtcacca
    10861 tcaatgcaga gatggtcaca atcccgatgt actcacccac gaagaacaga ccgaacttca
    10921 taccggaata ttcaatgtgg taaccatccg ccagttcctg ctcggcttcc ggctggtcaa
    10981 acgggtgacg gtgacatacc gccacgcccg cgatggcaaa ggtaataaaa ccaaagaatt
    11041 gcgggataac gttccacaca tgcgcctggc tgttgacgat gtcggtcatg ttgaatgaac
    11101 cggcctgcgc caccacgccc atcaaggaaa gcccgaggaa cacttcgtag ctcagggtct
    11161 gcgcagaagc acgcatcgca cccagcaacg agtatttgtt gttacttgac cagcccgcaa
    11221 acagcaccgc gtaaaccgcc agacctgcca tcatcaggaa gaacaaaatc ccgatgttca
    11281 ggtcggcaac cacccaaccc ggactgactg gcacaatcgc aaaggccagc agcagcgagg
    11341 taaaggcaat catcggtgcc agggtaaaga tgacgcgatc cgagaatttc gggatccagt
    11401 cttctttaaa gaacattttg atcatgtccg caaccagctg gagcgaaccg ccccagccaa
    11461 cacggttagg tccgtaacgg ttctggaaca gacccagcag gcgacgttcg ccaaagctca
    11521 tgaatgcccc gcaggtgaca accaccagca ggatcaccac cgctttgagg atggtcagca
    11581 ggatctcaat cagttccggt gatatccaac tcattgttgt gcctccttga gatcctcaag
    11641 atgcgcgcca gccagcaccg gagcaatgcc ggacataccc atcggcaagc ccacctgccc
    11701 tgccgtcagt ccttcggcga tttcaaccgg cagcgtgacc gtgttgccat cgtaactaaa
    11761 ggagacgcgt gtacctgcgt tcacacccaa cttcgcggca tccgctgggt tgagtttgat
    11821 gtacggctgc ggcatacggc tctggaagac cggagcacgc tgtgacaatt catcgctgcc
    11881 aaacaggtgg taatacggcg cgatacgcca tttcccgtcc tgcggctgga agcgtgccgg
    11941 tacgctggtg aagtaatcca gaccattttc gctggtttca aacagacgca cgcccggatc
    12001 gccaaagcgc agtttgccgc ccacttcgtc ctggaatttg ttccacgcct gcggggagtt
    12061 ccagcccggc gcccaggcaa acggcacttg cgaacggtgc gcagtcggct ggttgttacc
    12121 ttccatcgag aaggtgaaca tggtgtcaat atcctgcggc tgacgcggct catgaacgct
    12181 gatattggcg cgcatggcgg tacgaccgct gtaacggtgc ggttcacggg ccagtttctg
    12241 cccacgaata cggaatgtcg catccggcgc agcatctttg atacctgcca gttccgggat
    12301 tttcgccaca acagcgtcaa tcacatggtc gagctgcgtc cagtccactt cacggctcag
    12361 cagggtgctg tgcagcgagt gtaaccagcg ccagctttcc agcatgacag ttttgctgtc
    12421 gtaataagca ggatcgtaaa cctggaagaa acgttgggcg cggccttcgt tgttgatcac
    12481 cgtaccgtcg ctttcagcaa agctggcagc agaaagtacc agatgggcgt tttccataat
    12541 cgctgtgcgt tgatgatcaa ccaccatcac cagcggtgct ttagccagcg cagcattcac
    12601 gcggatagca gaagcgtgac gatgcagatc gttttccaac accaccaccg cgtcggcgcg
    12661 tccggtttcc agttcggtta acgcttcttc aagcgaaccg ccacccataa tgcccagccc
    12721 catgctgttg acggaacggg caatcatggt gataccgacg tcagcgccgc gacctttcag
    12781 ggctttcgcg acgttagccg ccgcctgaat cacctctaag ctaccggcgt tcgtcccgga
    12841 gataatcaac ggtttcttcg cacctgccag tgcctgcacg atgacgtcga ttttgctttg
    12901 cagctcaggt tcgataccgt caaccgctgg tgcagagtta tccagcgcat gggcgatggc
    12961 aaaacctaaa cgcgcctgat cttcaaccgg tgcgcggtaa gtccacgccg cgatatcatc
    13021 cagacgggtg tcatcaacgt tggtaacaaa cagcggatgc ttcgcacgtt gaccgatgtt
    13081 gaggattgcc gcaatctgcc agtcagccac tttctgtgct gccgccattt cgcgcgcttt
    13141 acctttcaca gcctgacgca ctgccagcgc gacgcgcgcg ccggtctggg taacgtcttc
    13201 gcccagcacc agtaccgcat cgtaagattc gatttcgcgc agagccggag tataaatgcc
    13261 gccttcacgc agcactttca gcgccagttg cagacgttcc tgctcaccgt gagcgatacc
    13321 ggtgtagaag ttttcttcgc ccaccagttc acgcagcgca aagttgcttt ccacgctggc
    13381 acgcggagaa ccaataccga tcactttctt cgactgacgc agaatatctg ccgcgccctg
    13441 cattgcctgt tcggcgttga gggtaatgaa atcatcgcca cgacgctgta ctggctgacg
    13501 cggacgatcc ttcaggttga cgtaaccgta accgaaacga ccacggtcgc agaggaagta
    13561 gtggtttacc gtaccgttgt aacggttttc gatacgacgc agttcgccgt aacgttcacc
    13621 ggggctgatg ttacagccga tggaacattg ctggcagatg ctcggcgcaa actgcatatc
    13681 ccatttacgg ttgtaacgct cggagtgcgt tttgtcggta aatacgccgg tcgggcaaat
    13741 ttcgaccagg ttaccggaaa attcgctttc cagcgtgccg tcttccgggc gaccgaagta
    13801 gacgttgtcg tgcgcaccgt aaacgcccag atctgtaccg tcagcgtaat ctttgtagta
    13861 acgcacacag cggtagcagg cgatgcagcg gttcatttcg tgagagatga atggccccaa
    13921 atcctgatta cggtgggtac gtttggtgaa acggtagcga cggaagctgt gtccggtcat
    13981 cacagtcata tcctgaagat ggcagttacc gccctcttca cataccggac agtcgtgcgg
    14041 gtggttggtc atcaaccact cgaccacgct ttcacggaac tgtttcgctt cttcgtcgtc
    14101 aatggaaata aaggtgccat cggaagccgg tgtcatacag gacatcacca ggcgaccacg
    14161 cgtgtcttcc gcgttttggt attgcttcac cgcacactgg cggcaagcac cgacacttcc
    14221 cagcgccgga tgccagcaaa agtaaggaat atcaaggccc agagacagac aagcttccag
    14281 caggttgtcc gctccgttga cctcgtattc tttgccgtct acatgaattg tagccattag
    14341 catgcttcca gttttctcag tcagagactg agcgttaatc gaaattcggt taccagcgct
    14401 ctttcagcag gttcggctga atcccattaa tcaaatgggt attgctgaac ggctgtttga
    14461 ttcccgcctc aaattcttcg cggaaatatt tgatggcgct ctgtaacggc tccactgcac
    14521 caggtgcgtg ggcacagaaa gttttacccg ggcctaagaa tcgacacagt tgctcaagtg
    14581 tttcgatatc gcccggctga ccttcaccac gctccagcgc acgcagaatt ttcacgctcc
    14641 acggcagacc gtcgcggcac ggcgtacacc agccgcagga ctcacgggcg aaaaactctt
    14701 ccaggttacg caccagcgac accatgttga tctcatggtc aaccgccatc gccagcgccg
    14761 tacccagacg gctgcccgct ttaccgatac tttcgaattc catcggcaga tcaaggtgcg
    14821 cttcggtcag gaagtcagtc cccgcgccgc ctggctgcca ggctttaaat ttcagaccat
    14881 cacgcatacc accggcgtaa tcttcgagga tctcgcgtgc ggtggtgccg aacggcagtt
    14941 cccacagtcc cggatttttc acccgaccgg agaagcccat cagcttggtg ccagcatctt
    15001 tacttttcga gatgttctga taccactcca cgccgttagc gaggatcgcc ggaacgttac
    15061 acagggtttc gacgttgttg acacaggtcg gtttacccca tgcgccggag gttgccggga
    15121 agggtggctt cgagcgtggg ttagcacgac gtccttccag ggagttgatt aacgctgttt
    15181 cttccccgca gatgtagcgc cctgccccgg tatggacgaa cagctcgaaa tcgaaacctg
    15241 ttcccataat gtttttgcca agcagacccg cttcggtggc ttcggcaatg gcacggcgca
    15301 gattaactgc cgcttcgata tattcgccac gcaggaagat gtagccacgg taagctttca
    15361 gcgcaaacgc ggagatgagc ataccttcca ccagcaggtg cggcagttgc tccatcaaca
    15421 ggcggtcttt ataggtgccc ggctccattt catcggcatt acacagcagg taacggatgt
    15481 tcatggattc gtctttcggc atcaggctcc atttcaggcc agtcgagaag cccgcgccgc
    15541 cgcgcccttt cagaccagcg tcttttacct gattaacgat ttcgtccgga gacagcccgg
    15601 tcagcgcctt acgcgcgcct tcgtaaccgt ttttgctgcg gtattcgtcc agccacactg
    15661 gctgtttgtc atcgcgcaga cgccaggtca gcggatgcgt ttcgggagta cggataatgt
    15721 ttttcattta taccgctcca gcagttcagg gatcgcttcc ggggtcagat gcgcgtgagt
    15781 gtcctcatcg atcatcatgt ttggcccttt atcacagttc cccaggcagc aagttggcag
    15841 cagcgtaaag cggccatcaa atgtcgtttg ccctggtttg atgttcagct ttttctcgag
    15901 cgccgcctga ataccctgat aaccgttgat atgacagacc acgctgtcac aataacggat
    15961 cacatggcga ccaaccggct ggcggaagat ctgactgtag aacgttgcca caccttcgac
    16021 gtcgcttgcc ggaataccca gcacatcggc gatcgcgtgg atcgcaccat ccggcaccca
    16081 gccacgctgc ttctgaacga ttttcagcgc ttcaatggac gccgcacgcg ggtcttcgta
    16141 gtggtgcatc tcgtgctcga tcgcttcacg ctctgccgca ctcagctcaa aagcctcggt
    16201 ttgtggttgt tgattctcgt gcataattag cggtccacat ctgacataac aaaatcgata
    16261 ctgcccagat aaacaatcag gtcagacacc aggctgccgc ggatcgccgc cggaatttgc
    16321 tgcaaatgcg caaagctcgg ggtacgaaca cgggtgcggt aactcatggt gctgccgtcg
    16381 ctggtcaggt agtaactgtt gatccctttg gtcgcctcaa tcatctggaa agattcattg
    16441 gcaggcatca ccggacccca cgacacttgc aggaagtggg tgatcagggt ttcgatatgt
    16501 tgcagcgtgc gctctttcgg cggcggcgtg gtcagcgggt gatccgcttt gaacgggcct
    16561 tccggcatgt tgttgaggca ctgctcaaga atgcgcagac tctggcgcag ctcttccact
    16621 ttaagcatta cgcgggtgta gcagtcagaa acgccaccac ccaccgggat ttcaaagtcg
    16681 aagttttcat agccagaata aggacgcgcc ttacgcacgt cgaagtcgat cccggtagca
    16741 cgcaggcccg cgccagtggt gccccactcc agcgcctctt tcgcgccata ggcggcaacg
    16801 ccctgggaac gacctttcag aatggtgttt tgcagcgccg ctttctcgta agacgccaga
    16861 cgtttcggca tccagtcgag gaactcacgc agcaggcgat cccagccgcg cggcaggtcg
    16921 tgcgctacgc cgccaatacg gaaccacgcc gggtgcatac ggaaaccagt gattgcttcc
    16981 accagatcgt aaattttctg acgatcggta aaggcgaaga acactggcgt cattgcgccg
    17041 acgtcctgaa taaaggtcga gatatacagc aggtgactgt tgatgcggaa cagttcggag
    17101 agcataacgc gaatgacgtt aacgcgatcc ggcacggtga tcccggccag tttctctacc
    17161 gccagcacgt aaggcatttc gttaacgcag ccgccgaggt attcgatacg gtcagtatac
    17221 ggaatgtagc tgtgccagga ctggcgttcg cccattttct ccgcaccacg gtggtggtaa
    17281 ccgatgtctg gtacgcagtc gacaatctct tcgccatcga gttgcaaaac gatacggaaa
    17341 gccccgtgcg ccgacgggtg gttcggaccg aggttgagga acatgaagtc ctcgttttcg
    17401 gtgccgcgct tcatccccca ctcttccggt ttgaaggtca gggcttccat ctccagatcc
    17461 tgtttggctt tggtcagctc aaacggcgag aattcggtag cgcgcgccgg ataatcttta
    17521 cgcagcgggt gacctttcca ggtttgcggc atcatgatgc gtcgcaggtt cgggtgaccg
    17581 tcgaaagtaa tgccaaacag atcccaggtt tcacgctcat accagttagc gttcgggaac
    17641 agtttggtga aggtcggtac gtgcaggtcg ttttctgcca gcgccacctt cagcatgatg
    17701 tcgcggttac gatcgataga aatcagatgg tagaaaacgg aaaaatccgc ggcaggtaac
    17761 ccttcgcggt gtgtgcgcag acgttcgtcc atgccgtgta agtcaaacag catgacgtaa
    17821 ggtttcggca gtttctttaa gaaatcgcca acttccagta attgttcacg cttgatccac
    17881 acaacgggaa ccccggtgcg agtcgcctga acagtaaagg catccggccc aaaacggttg
    17941 cgcagttcgc caatcaccgg atcatcaaga tgatcgcggg tctgccaggc gggttcttgc
    18001 gcggttaagt cggtcatatt gttcaccatt gcaaatggtc cgtggtgact gtcggcgcag
    18061 taagcttcgc gaaatagatt taggaataag cgaagaaaaa tccctttgcc gacaggcgca
    18121 aattaaatct cgtcaggtgt acgcaggtta gttacggcaa tgcgttcacc gcgcttgcgt
    18181 tcgcgctctg attgcatatt ggcgcgataa acgccctgat cgccaaccac ccaggagagc
    18241 ggacgacgtt ctttgccgat agattcctgc aacagcatca gtgcctgcat gtacgcttca
    18301 ggacgcggcg ggcagcccgg gatatacaca tcaaccggga tgaatttatc gacgccctgc
    18361 acaacggaat aaatatcgta cataccacca gagttggcac aggcacccat tgagataacc
    18421 cattttggtt ccagcatctg gtcatacaga cgctgaataa ccggtgccat tttggtaaag
    18481 caggttcctg caaccaccat caggtcagcc tgacgcggcg aagcacgcaa tacttctgcg
    18541 ccaaaacgcg ccacgtcatg caccgcggta aacgaagtca ccatctcaac gtaacagcag
    18601 gaaagaccga agttatacgg ccaaattgag tttttacgac cccagttaac catgtcattg
    18661 agcttgccca taaacacgtt tttgttaact tcttgctcca gagggtcggt tacgatctcc
    18721 tgcttttgca gggggtaacg gtcgttctca ccgttgggat ctatgcgggt gagcgtataa
    18781 tccatcttaa tgcctcgcgg ttagcgttga cgattagcga tactgttcgt ttccgggttc
    18841 atacgctcgc ggcgtgaacg cgcgggcgtc cagtccagcg cgccaatacg caccagataa
    18901 accagacctg ccagtaacac aaaaataaaa attgcagctt ccacaaagcc tacccagccg
    18961 ctttcgcgga tagaggttga ccatgcgaac agatacagcg cttcaacgtc gaagataacg
    19021 aagaacatgg ccaccagata aaacttggcg gacaggcgta agcgggcgga gccgaccgag
    19081 tcgataccgg attcaaacgg cacgtttttc gacctcgcgc gtgcgcgacc gcctaaaaac
    19141 caaccgccta ccagcatcag gcaacacagg ccaatggcaa cgataagaaa gatagcgaat
    19201 gcccagtgat gagcgatgac ttcagtggat gttgacatac tcattgctta ctcatcaaaa
    19261 gtagcgccag attcactgct cttcacggca gatggacgcc acatcgattc atggggagga
    19321 ataaaaaaaa ccttacaatc actgtagaaa ttcttttata cagctaattg atgtggtctt
    19381 ttactccttt ctataacctt ttgtcaactt taacaaaagt ttcttcacat tagtttacat
    19441 aatatcaaca ccattagcat ttaatgccct ttcaccccag atccttgacg actccaggat
    19501 aattagatgt tgttgaatcg tgtccgttgt gaagcaatgg aaaaaatacg ggtctatttt
    19561 gacaggaatt tgtgtcgatt cctcccccca aaagagagta ttttcttgat ctgtgacacg
    19621 cttttgtcat tccataacaa aaacgcagca acaaatttac gtatttttta acatcattgt
    19681 agcaggtgat ttttttcagg cgattatttg tgcgttcggg acgtgaatct ctggtgattg
    19741 aaaaatgaac agttttgtgc gttctgcact atgcgaggaa ggatttttac taaaaaaaag
    19801 ccgctggggt ttaaaacacc cccagcggct cgttttttac actattgtct caggaattat
    19861 ctatcgtccg tcgattactc gatatccctt tcaatcaaca atgaatcatc cccttccgga
    19921 gcagacattg ggctgtattg ccacggatta tggtagctct ccatcgcctg atagatcacc
    19981 tgggccagct cattattact ggacgggtca tagcacagca aatattcggt atcaggtagc
    20041 ggcggtaagc catctactcc actcagcaca cgcaggtccg ggctcatcat ttcaaccggc
    20101 cttgccgtca cgccaagacc ggctttcact gccgcacgaa cggccggaag cgtcgaggcg
    20161 acataagcca gtcgccatgg aatatctgct ttattaagcg tcgccagcac catatcgcga
    20221 aacggacttg gatcatccag caatacaaga gggatcggct cacctttttg caatacgtat
    20281 tccgctgcgc agtaccagtg tgttggcgag gtacgcaggt tcaatgcctt aaaggtagaa
    20341 ggacgatggg tggttaccat caaatccact tcctgggatt ccagcatttc tgccatatag
    20401 gcattacgtt taacgcggac atccagcgct aatttcggat aaaccgaact cacgcgattt
    20461 aacaggaaag gtaagatcgt atcggcagat tcatctgaag caccgatagt taacacgccc
    20521 tgaagattac tgaacattaa tgatgagcag gcctcatcat taaaacgcag gattttcctg
    20581 gcgtaaccaa gaagttgaat gccatgttca gttaacagtt tgttgcgacc gtgacgagcg
    20641 aacagttctt tcccaacgag ttgttccaga cgctgcattt gctgacttac ggcggactga
    20701 gtacgacaca cagcggcagc tgcggcagca aaagtgttca gatcggcaac agcaacaaat
    20761 gttctcagca gatcgaggtc gaggttaatt atcggacgat ttgcacttat catatattat
    20821 cacttactgg cggctcatac tgagctggtt aatgctgtgc acacacaaac aagcaattcc
    20881 atttgtaatg tgcctccctg gcagtttcat ccggaacccg gacgaaagta aaaatgcata
    20941 tgagttgcac taaaaaagcg actcacattg ttccgttata atgcctgaag tagatcacag
    21001 aatatatctt cagggatcgc atatctatta agttactcac tcttttctat ttatgacatg
    21061 cgcgtgtttg tataaatgta aatgtgagtc cttgttccac tctcgtgcag catcgctggt
    21121 catacgcgaa cacgtacaaa cagcaatggt gaggcggcat caagagcagg gatccgtcat
    21181 ttatgcgagc attttacccc aaaaaccttt tatttataag ggtcattgcg aattatctga
    21241 tgcaaagtta tgttatgtta ggcaaagtaa tcttctatta ttaataagca catcaaaacc
    21301 tttttgaata ttaaataata attaattagc atcatcctca ttcattaatt ccgcttaaca
    21361 atagtttcac accttgcccc cattacgaca cctcggaaat catcacgctg ttaaactctc
    21421 cgtaatgcgg aaatatcatc atcgcgtttc attagtgaat tcttaaatga ggcat
//
LOCUS       DAPHKZ010000072        21182 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.072, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000072 DAPHKZ010000000
VERSION     DAPHKZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21182
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.072"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(94..3894)
                     /gene="yhdP"
                     /locus_tag="RH288_002868"
     CDS             complement(94..3894)
                     /gene="yhdP"
                     /locus_tag="RH288_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HDV4031908.1"
                     /translation="MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKI
                     ESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLRFRTNTPITSGGSDDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSG
                     QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQ
                     ADDIDLKPWLGKWMQDNIALETAQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKQT
                     HTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAWIPEQDVGGKDNKRS
                     DELRIRASNLELAGLEGIRPLAAKLSPALGDVWRSTQPSGKINTLALDIPLQAADKTR
                     FQASWSDLAWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIAD
                     GQATISWLSNNKGFQLDGRNIDVKAKAVHARGGFRYLQPANDEPWLGILAGISTDDGS
                     QAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFEVLVPLR
                     NAKFAFQPDWPALTNLDIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLI
                     DADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEV
                     TLRNNSLFIKPLDSTLKNLSGKFSFINSDLQSEPLTASWFNQPLNVDFSTKEGAKAYQ
                     VAVNLNGNWQPAKTGVLPEAVNEALSGSVAWDGKVGIDLPYHAGATYNIELNGDLKNV
                     SSHLPSPLAKPAGEPLAVNVKVDGNLNSFELTGQAGADNHFNSRWLLGQKLTLDRAIW
                     AADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAASFPQHITLRTPMLS
                     LGNQQWNNLSIVSQPTANGTLVEAQGREINATLAMRNNAPWLANIKYLYYNPSVAKTR
                     GDSTPSSPFPTTERINFRGWPDAQIRCTECWFWGQKFGRIDSDITISGDTLTLTNGLI
                     DTGFSRLTADGEWVNNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLH
                     WRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRFDFRDTF
                     GEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVAPEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRK
                     EKAQ"
     gene            complement(3962..5431)
                     /gene="rng"
                     /locus_tag="RH288_002869"
     CDS             complement(3962..5431)
                     /gene="rng"
                     /locus_tag="RH288_002869"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HDV4031909.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGEEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQR
                     VLRDFADAELDRIRVDSRLTYEALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKR
                     TRESIEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHSLAEVEIFVGKQVKVQIEPLYNQEQFDVVMM"
     gene            complement(5421..6014)
                     /gene="yhdE"
                     /locus_tag="RH288_002870"
     CDS             complement(5421..6014)
                     /gene="yhdE"
                     /locus_tag="RH288_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /protein_id="HDV4031910.1"
                     /translation="MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQY
                     VVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQ
                     VMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASDEPLDKAGAYGIQGLGGCFV
                     RKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG"
     gene            complement(6023..6511)
                     /gene="mreD"
                     /locus_tag="RH288_002871"
     CDS             complement(6023..6511)
                     /gene="mreD"
                     /locus_tag="RH288_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDV4031911.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQ
                     QALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
                     VQ"
     gene            complement(6511..7614)
                     /gene="mreC"
                     /locus_tag="RH288_002872"
     CDS             complement(6511..7614)
                     /gene="mreC"
                     /locus_tag="RH288_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDV4031912.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDT
                     AVSPFYFVSNAPRELLDGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQPTPQQPATGNAATA
                     PAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ"
     gene            complement(7680..8723)
                     /gene="mreB"
                     /locus_tag="RH288_002873"
     CDS             complement(7680..8723)
                     /gene="mreB"
                     /locus_tag="RH288_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HDV4031913.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            complement(9028..10968)
                     /gene="csrD"
                     /locus_tag="RH288_002874"
     CDS             complement(9028..10968)
                     /gene="csrD"
                     /locus_tag="RH288_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HDV4031914.1"
                     /translation="MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQA
                     VATAIDTHLVSNDFSVLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGSSD
                     LFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIIVMLFLAVRWLQR
                     QLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLREIQNAREQHSRLDT
                     LIRSYAAQDVKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHS
                     QVEEQFFTLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIAGQLIKAVDT
                     LPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEK
                     GRGNVRWRTLIEQMLSRGGPRLYQKPAVTREGQVHHRELMCRIFDGNEEVSSAEYMPM
                     VLQFGLSEEYDRLQISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKS
                     QRKRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELL
                     KLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQG
                     DFFASSQPLDTNVKKYSQRYSV"
     gene            11120..12094
                     /locus_tag="RH288_002875"
     CDS             11120..12094
                     /locus_tag="RH288_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDV4031915.1"
                     /translation="MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQA
                     RVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
                     STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDEFAESRPLEKQVWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRA
                     QAWQRLVADLPESFYTQAAKEISLSEAPNFAEAIINNQIQGRTLVKVN"
     gene            13072..13542
                     /gene="accB"
                     /locus_tag="RH288_002876"
                     /gene_synonym="fabE"
     CDS             13072..13542
                     /gene="accB"
                     /locus_tag="RH288_002876"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDV4031916.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVM
                     QQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE"
     gene            13553..14902
                     /gene="accC"
                     /locus_tag="RH288_002877"
     CDS             13553..14902
                     /gene="accC"
                     /locus_tag="RH288_002877"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDV4031917.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA
                     SGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKLGLQEK"
     gene            15011..15253
                     /locus_tag="RH288_002878"
     CDS             15011..15253
                     /locus_tag="RH288_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HDV4031918.1"
                     /translation="MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLSGVAPGFTGFPR
                     WFEMACILTPLLFIGLCWAMVKFIYRDIPLEDDDAA"
     gene            15243..16694
                     /gene="panF"
                     /locus_tag="RH288_002879"
     CDS             15243..16694
                     /gene="panF"
                     /locus_tag="RH288_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HDV4031919.1"
                     /translation="MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQ
                     TIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFH
                     PIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK"
     gene            16706..17587
                     /gene="prmA"
                     /locus_tag="RH288_002880"
     CDS             16706..17587
                     /gene="prmA"
                     /locus_tag="RH288_002880"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDV4031920.1"
                     /translation="MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFAL
                     DPVVEKEEWCRITGRKN"
     gene            17916..18881
                     /gene="dusB"
                     /locus_tag="RH288_002881"
     CDS             17916..18881
                     /gene="dusB"
                     /locus_tag="RH288_002881"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDV4031921.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGY
                     RIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            18907..19203
                     /gene="fis"
                     /locus_tag="RH288_002882"
     CDS             18907..19203
                     /gene="fis"
                     /locus_tag="RH288_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HDV4031922.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            19289..20173
                     /gene="yhdJ"
                     /locus_tag="RH288_002883"
     CDS             19289..20173
                     /gene="yhdJ"
                     /locus_tag="RH288_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417728.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HDV4031923.1"
                     /translation="MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYN
                     IGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLF
                     TIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALI
                     DYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIV
                     LDPFAGSFTTGAVAVSSGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTG
                     NLSKRSRLSEVDPDLIAK"
     gene            20257..20436
                     /locus_tag="RH288_002884"
     CDS             20257..20436
                     /locus_tag="RH288_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HDV4031924.1"
                     /translation="MIRKYWWLVVFAVFVFLFDTLLMQWIELLTTETDKCRNMNSVNP
                     LKLVNCDELNFQDRM"
     gene            complement(20439..21101)
                     /gene="acrS"
                     /locus_tag="RH288_002885"
     CDS             complement(20439..21101)
                     /gene="acrS"
                     /locus_tag="RH288_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrS"
                     /protein_id="HDV4031925.1"
                     /translation="MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVT
                     RGAIYWHFENKTQLFNEMWLQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAK
                     IPRQQALLKILYHKCEFNDEMLAEVVIREKMGFNPQTLREVLQACQQQGCVANNLDLD
                     VVMIIIDGAFSGIVQNWLMNMAGYDLYKQAPALVDNVLRMFMPDENITKLIHQTNELS
                     VM"
BASE COUNT         5122 a         5604 c         5325 g         5131 t
ORIGIN      
        1 aacgccctat ccgacctacg gttatgttct ggctcgttgg cctttggcaa cgattatcct
       61 atgagattgg ggcaattacg cgccctcgtc aaatcattgc gctttttctt tacgcggttg
      121 gcgcaacact tcgttgattt gcggatcgtc cagcggaccc gaaatgtgat agcgcaaaat
      181 ggagactttg ctccacagcg gccccagcac tttactggcg gcaaacactg ccgcgccaac
      241 aatggggtta accgcaaaag ccgcagccac gcccaccgtc gcagaaatct ctggtgcgac
      301 aaccgcttcc atattcaggt cgcgacgtac cagatttacc gaccctttca tggcgatatc
      361 cgcctccagg ccatccacca gcgtgtcgtc ggtgtgcata acgccgtctt taatccacgc
      421 ggtgctgcga atggagtcaa aatagaaccc ttcgccaaaa gtgtctctga aatcaaaacg
      481 cagcttacgc atcagggcat ctacgctcaa taagcgcagc aattgcccgg catgtccggt
      541 attgatttcg gtaatttcgc ctttacccag ttgagtatga atgatgccat tcaacgtcgc
      601 ttcatctggc tgccagggtg ctttgcgcca gtgtaaatcg taatccacat taaatgacga
      661 ctggcgtatg ggcgtcgtga caccaaaaaa ttctgcggcg gcatcaattt tctgcccgcg
      721 cagttttcct ttcagcgagg tacgttcatt ccccggatta ttaacccatt caccatcggc
      781 agtaagccgc gagaaaccag tatcaatcag tccattggtc agcgttaacg tatcgccaga
      841 aatggtgata tcactgtcaa tgcgaccgaa tttttgcccc cagaaccagc actctgtgca
      901 tcgtatttgg gcgtccggcc agccacggaa gttaatgcgc tccgttgtcg ggaaaggtga
      961 tgacggcgtt gaatcaccac gagttttcgc cacgctcggg ttgtaataaa gatatttgat
     1021 attcgccagc cacggcgcgt tattacgcat cgctagcgtg gcgttgattt cacgcccttg
     1081 cgcttcaacc agggtgccat ttgccgtcgg ttgcgaaaca atactcaggt tattccattg
     1141 ctgatttccc agtgacaaca taggcgtacg taacgttatg tgttgtggga aactcgctgc
     1201 accaccgaca ctctccgcag cgcctttctg gaacagggcc agccactcgg caccattcat
     1261 cggcggcata ttgagttcaa cgccactttg ttccggcaac ggcgggagcg ttttactgtc
     1321 tgccgcccaa atagcacgat cgagcgtcag cttttgaccg agcaaccagc ggctattgaa
     1381 atgattatcc gcaccagcct gtccggttaa ttcaaagctg ttgagattgc catcaacctt
     1441 aacgtttacc gctagtggtt cacccgcagg tttggctaac ggtgaaggta agtgactgct
     1501 cacattcttt agatcgccgt tcagctctat gttataggtc gcaccagcat gataaggcag
     1561 atcaatgccc actttaccat cccacgccac gctgccactc aatgcttcgt tcaccgcttc
     1621 aggcagaacg ccggttttcg ccggttgcca gttaccgttg aggtttaccg ctacctggta
     1681 ggcttttgcc ccttctttgg tggaaaaatc cacgttcaac ggctgattaa accagcttgc
     1741 tgtcagtggt tcactttgca gatcgctatt gataaagctg aatttaccgc tcaaattttt
     1801 cagggtgctg tcgagtggtt tgataaacag actgttatta cgcagcgtca cttcaccttt
     1861 cgcggttacc agttcgccgt tcagcgggat atcaagatgt aagcgagcat tcacatcgcc
     1921 gtcgagctgg agttcttgca gggtcgcacc cagagaatct ttcagcggtg tctcatcaaa
     1981 gtaagggcca acggctttac ccggaccttt aatgtcagcg tcaatcagca gtttttcttt
     2041 tgagtagtca gggatcactg cggtaagatt actcgcgcgc acgccgccca gattaacgcc
     2101 atcggttttc atccataaac cgtcgttaat aaagtccagt tcaatatcaa ggttagttaa
     2161 tgcaggccag tccggctgga aggcaaactt cgcgttgcgc agcggcacca gcacttcaaa
     2221 ctgaccttcg ttgtgtttat aggggaagag ttgcggattg ccaccataaa ccagcgtcgc
     2281 gttatccgct tcaccgccct gaatcgcgcc acttaagtaa tcaaccaggt ctttacccat
     2341 caagttttcc gggaaatagc gccaggcttg tgaaccatca tcggtactga tgccagccag
     2401 aatacccagc cagggttcat cgttagcagg ttgcaggtaa cgaaaaccgc cgcgcgcatg
     2461 gacggctttg gctttaacgt caatattacg cccatccagc tggaaacctt tgttattgct
     2521 cagccagctt atagttgcct ggccgtcggc gatttctagt ggcgcacgga ataccgtttc
     2581 gtaaggcatc tttgcctgct tcatcgacgc ggtaagcaaa ccattttcaa cgctgccgga
     2641 aagcgtcccg gagaagtgtt ccgcacccgg taataatttc cattgcttcc aggccagatc
     2701 gctccacgat gcctgaaaac gggtcttgtc tgccgcctga agcgggatat ccagcgccag
     2761 agtgttaatc ttgccgctcg gttgtgtgga gcgccaaaca tcacccagtg caggtgaaag
     2821 tttcgcggcc agcgggcgta tgccctccag gcctgccagc tccagattac tggcgcgaat
     2881 ccggagttcg tcactgcgtt tattgtcttt gccgccaacg tcctgttccg gtatccaggc
     2941 cagcgtcaat gctccgctcg gccagggttt gccgtccatc gtgatccgtg tatcgggaat
     3001 agagaactgc cagcccggat tttcacgcgt aatatgcgcg gtcagattat ccaccgacag
     3061 cgtatgcgtt tgcttctcgc ccaaccagct ggcaccgccc tgtttcagcc agacgtcacc
     3121 gccggttaca tcgcctttgt cgatcgtcat ccagccttca agggagaact gtgccgtttc
     3181 cagcgcaata ttgtcctgca tccatttacc gagccacggc ttcaggtcga tgtcatccgc
     3241 ctggagccag acgcgaccat tgcttaacaa cccctcatca tcgcgcaaat ccatgcgcac
     3301 ctgcatcacg ccgtgctgtc cggtaaggct ggagaggctt accaggcctt ccgcacggtg
     3361 tcgacgtgga tcgttcagcc aggtgagttg tgggatcgcc agctcggcgc gctgaccgga
     3421 tggcgtcagg aaactgactt cactgtcgcg aagatcgaaa tggtcaaatt gacgaagaaa
     3481 cagatcgctg atgtgactgg cttccagact gtcatcacta ccaccgctgg tgataggagt
     3541 gttggtgcga aagcgcagct gccagaaagt gaggtcgcga aactgccagc gcatatgtaa
     3601 caggctctgc cagacatcca gcgccagagt aacgcgttta accgaaaatt cgccgccatc
     3661 ttttagttct gcacggatgt cgtgtgcttc aagcgtcggg ccaaaattct gccagctggc
     3721 tgagagctga ctggcttcta ccggcatgcc agtcgcggat tctattttgt tgaggatttc
     3781 cggacgccag gcgtcaagat gcggtaaagc aatacgcagg ccgctaacca gcagggcagc
     3841 gatcacaacg agcgcggctc cagtaagcag taaaatcccc ggcaatcgcc tcacccgtca
     3901 ctccttgtct gctaaaaatg tgactcaaaa accctttgcc ggatggcggc ccagcatctg
     3961 tttacatcat tacgacgtca aactgctcct ggttatagag cggttcaatt tgtactttaa
     4021 cctgtttgcc aacgaaaatt tccacttccg ccagcgagtg tgactcttcg cctttcaagg
     4081 cttcagctac tgccggagaa gcatagacca ggaaacggtc ggagtcgtaa gcatggtgga
     4141 cacgaacaat ctcgcgcatg atttcatagc ataccgtttc cacggttttc accgttccgc
     4201 gaccgtggca ggttgggcat tcgttacaca gtacgtgctc aatgctttcg cgggtgcgtt
     4261 tacgcgtcat ctccaccagc cccagcgccg aaaaaccatt aacgctggtt ttcacccggt
     4321 ctttgctcaa cgcctgctcc agcgagtgca gcactcggcg gcggtgatct tcattattca
     4381 tatcgatgaa atcaataatg ataatcccgc ccagattacg caaccgtaac tggcgagcga
     4441 tagcctgcgt cgcttcaata ttggtattga aaatggtgtc gtccagattg cgatgaccga
     4501 caaacgctcc ggtattgatg tccacggtgg tcatcgcttc ggtctggtcg ataatgagat
     4561 aaccaccgga tttcagttct actttgcgtt ccagcgctcg ctggatttcg ttttcgacat
     4621 caaagagatc gaaaatcggc tggcgtcctg tgtaatgctc cagcttgctt gtcatctcgg
     4681 gaatgtactc cgaggtgaac tcaagtaacg cttcgtaagt caggcgtgag tcaacgcgaa
     4741 tgcggtccag ttcggcatcg gcgaaatcac gcagaacacg ctgcgccagc gccagttcgc
     4801 cgtacagctg ataacgggtc tgcgggcgtt ttttacgctc cataactttg gtccagacac
     4861 gtttcagata agcggcatcg gaggccagtt cagcctcgcc aaccccttcc gctgcggtac
     4921 ggatgataaa cccgccctgc tcgtcgcaat actctgcgac cacttttttc aggcgttcac
     4981 gttctgattc gctttcaata cgttgggaaa ccccaacgtg agaagcccct ggcataaaca
     5041 ccagatagcg agaagggagc gtgatatcgg tggtcaggcg cgcaccttta gtgccaagcg
     5101 gatctttcac cacctgcacc atcagatctt gcccctgacg aaccagttcc gagatgtcgc
     5161 gcaccgtgaa ttgcttttgt tcttcacccg ccacacattc ggtgtgcggc atgatgtcgg
     5221 atgcatgaag aaacgcggct ttatccagcc caatatctac aaaagccgcc tgcatacccg
     5281 gaagtacacg acttacacga cccttgtaga tattgcctac tattccgcgt cgcgcctcac
     5341 gttcaatatg aatttcctgc agaataccgc catcaatata cgccactcgc gtttccgaag
     5401 gcgttacgtt tactaacaat tcagccgtca tgtttatccc ttttctcacg cagtgcgtta
     5461 aaattactta ataattcata cgtttcaacc agcggtaagc cgactacggc gtgatagctg
     5521 ccatttatct tcctgacaaa acagccaccc agcccctgaa taccgtatgc acctgcttta
     5581 tctaacggtt catcgctggc gacatagccc gcgatgtctt cgtctgttaa cgttctgaaa
     5641 gtcacatcgg tgaccaccag gcaatcgaga atgtgctggc tgtcggccaa cgccactgct
     5701 gtcatcacct gatgggtctg acccgataat ttgcgcaaca tctgcgccgc atgctctgcg
     5761 tcgcgcggtt tctccagcac ttctccgttc aggataacga tagtatccgc acccagcacc
     5821 gggagatcct tcgccgtttg cgcgacacct gcccgtgctt tctcgcgcgc cagacgcaca
     5881 acatactgct gcgcgctctc ctgcggctga cgctgctcct caatgcccgt aacaatacgt
     5941 tcaaaggtca cgccaagttg cgcaagtaac tcctgacgac gcggagaacc ggaagctaaa
     6001 tacagagaag tcatagaaac ctttattgca ctgcaaactg ctgacggact ttgcgcatca
     6061 gcaagaaaat ccacggccag agcaccccat tgactacact actccagaac acttccggtc
     6121 tgaaagagac gttaatcact aaaaactctg cccagaaaac aataatatcc accaccagcg
     6181 aaagcaacat gacgaccagc gcctgctgcc ataatgcgag gttgcggaaa agctggtatt
     6241 tcagcgccac caggtaagca atgatgctca tcgccaatac gcgtacgcca agcgtcgagc
     6301 cgctgatcag atccagtatg gcacccatca caaaacctgt gcccacattt acgcgatgag
     6361 gcaaggccag gatccaatac aacaagatga gtaacaccca gtttggccgg aaaacaatca
     6421 ggttatccgg ccagggcatg atttgcagca acagcgcaat gaggaaagag agccagatta
     6481 cccagcgtcc ctggctacga tagctcgcca ctattgccct cccggcgcac gcgcaggcgg
     6541 ttgagcacca ctttgcggcg gcgtagccct ttgtggagag cgattagcag caggctgtgt
     6601 cggcgcagca ggcgcagtag ctgcatttcc tgtcgccggt tgctgcggag tcggctgagc
     6661 gatccccgtt gccggttcag gtaactttgg ccccatcgcg tctggcgaag gcaatacctg
     6721 cggcatcatc tgcatcagac gttcattagc aacacgatgc acctcttccg gcgtcatcgg
     6781 gttagcgccg ttacgatctg ccccccacag cagcagcaga taacgcaaac gttgcagccc
     6841 tgcagtcgga cgcgcctgaa tcacagtata agcgcgctgg gtatcgagtt ttacggaaga
     6901 gacaaccgcg accggatagc cttccgggaa acgaccgccc agaccggaag tcaccagcac
     6961 atcaccaaca cgaatatccg tattcgccgg cagatgctca agctgcaaat catccgtaca
     7021 accgttaccg gctgcaatta cgcggatatc gttgcgcagc acctggattg gcagcgcgtg
     7081 ggtcgcatca caaatcagca gcacgcgact ggtcagttta gcgacggcca ccacctgacc
     7141 aacaacacct ttgtcgctga tgaccggctg gccttcataa acgccattaa cgctaccttt
     7201 atcgataaca acttgatcgc tataaggatc gttaaccgtg gagataacct gagtcaccat
     7261 tttctgctca tcctgacgca gcggggaacc cagcagctcg cgcagacgcg cgttctcctg
     7321 tttgtattgt ccaagcatca gcagttcact gtttttcagc aacagttcct gacgtaacgc
     7381 ccggttttca agttctaatt ggtcacgcga ggccagcgtc tgcgatacgc catccagcaa
     7441 ttcacgagga gcattggaaa caaagtagaa aggactgacg gcggtatcca tataagtacg
     7501 gatttgactg aacgtcccca ggcggctgtc ggcaataata atgccgagcg ccaccagcac
     7561 cgccagaata aggcgaatct gtagcgacgg gccacggcta aaaattggct tcataagtta
     7621 tgcgtattct cgtatcagac caggcagggt aaacagacac ttcccctgcc tgcatccgat
     7681 tactcttcgc tgaacaggtc gccgccgtgc atgtcgatca tttccagcgc tttgccgcca
     7741 ccgcgcgcca cacaggtcag cgggtcttca gcaacaacga ctggaatgcc ggtttcttcc
     7801 attaacaaac ggtcaaggtt acgcagcagt gcgccaccac cggtgagcac catgccgcgc
     7861 tcggagatgt cggaagccag ttccggcggg cactgttcca gtgcaaccat taccgcgctc
     7921 acaataccgg tcagcggttc ctgcagtgct tcgaggattt cattggagtt cagggtaaaa
     7981 ccgcgtggaa caccttctgc caggttacgg ccacgaactt cgatttcacg gacttcatcg
     8041 cccggataag ccgaaccgat ttcgtgcttg atacgttctg cggtggcttc accgatcaga
     8101 gaaccgtaat tacgacgcac atagttgatg atagcttcgt cgaaacggtc accaccaatg
     8161 cgcacagaag aggagtaaac cacaccgttc aaggagataa cagcaacttc agtggtacca
     8221 ccaccgatat caaccaccat agaaccggtc gcttcagaaa ccggcaggcc agcaccaatt
     8281 gcggcagcca tcggttcttc aatcaggaag acttcacggg caccagcgcc ctgcgcggat
     8341 tcacgaattg cgcggcgttc aacctgggtc gcgccaaccg gcacacaaac cagaacgcgc
     8401 gggcttggac gcataaagct gttgctgtgc acttgtttga tgaagtgctg gagcattttt
     8461 tcagtcacga agaagtcggc gataacgccg tctttcattg ggcgaatggc agcaatattg
     8521 cccggcgtac ggcccagcat ctgcttcgcg tcatgaccta ctgcagctac gcttttcggt
     8581 gaaccggcac gatcctgacg aatggccacc acggaaggct cattcaatac gatgccttgt
     8641 ccttttacat aaatgagggt attcgcagta cccaggtcaa tggacaagtc attggaaaac
     8701 atgccacgaa attttttcaa catactaagg gataatcctg aaagctgggg cggaaaagaa
     8761 aatccgctta ctttaccaac cacacgcagc agcgacaagg cgcaaaaatc atctgctacg
     8821 gtgaaaatta gtgcagttcg tttcctttgt tacaaatctc tgcctgagtc cagaaaggct
     8881 taatgcatca gcagcattcc tcgcctgttt gcaaccgcgt aaggtcattc atctgcatat
     8941 gtgctgcaac aatctggcga gcagacaagc acactcccat gagacgcagc gcgcgttatt
     9001 ctacgtgaaa acggattaaa cggcaggtta aaccgagtat ctttgtgaat attttttcac
     9061 gttagtatca agtggctgtg aggacgcgaa aaaatcccct tgcccgcctg taacaccgcg
     9121 ctgaatcagg gtctgccact cgcttcgcga acgcacgccg gtggcgtaaa cctgggtgct
     9181 ggtcccggag caggcttcca ccaggctttg aaccagcagc tggttctccg ttcgcttctc
     9241 aatgtttctg accagccccg gatggagctt gagtaactca acattaagtt ctttgatcca
     9301 actggtactt accagcgtca aaccagcctg gttgacggct acccgtaccc ctaaagcatt
     9361 cactaaacga ataacaggtt gtaaacgact gatatgttga cctacatcgg cctctgcaag
     9421 ttcaataatt atgcgttttc gttgtgattt ttcacattgc attaacgtat cgcgcagcca
     9481 acgctgaaaa cgcgggcgaa tcagcgactc aacggtaacc tgaatcgcca gattttcctc
     9541 tggccagtaa cgcaatagtg gaataagacg gctgatttgc agacggtcat actcttccga
     9601 taagccaaac tgcaagacca tcggcatata ctccgccgag ctaacctctt cattaccatc
     9661 gaagatgcgg cacatgagtt cgcgatgatg aacctgacct tcgcgagtaa ccgccggttt
     9721 ttgataaagg cgcgggccgc cgcgactgag catttgctcg ataagcgtac gccagcgaac
     9781 attaccgcgt cctttttcag gcaacgagtc atcgtaaata gcccagctat tgccgccctg
     9841 caatcccgca ttacgcgtgg cagactctgc atgttccatt acctgctcgg tatcctgacc
     9901 actacgccag gcgcagatac caatgtggat catatcgtcg cgatcgagca ttttattgtt
     9961 cggcaaggta tcaacggctt tgattaactg accggcgatg ctctctgcct cttttaacgt
    10021 ccggtgcggt aacagcgcag caaaatcact gcggtggtaa cgcgccagca gtgcgccagg
    10081 gtagcgcatc ataaatgtcg acagcagatt cgtcagagtg aagaactgtt cttcaacctg
    10141 gctgtgcccc caggtatcgc tcaacatatt gaaatccggc agacgaatca tcatcacgat
    10201 cccgtgggta cctactttct cctgatcttc cagtaacgtt gctaactgat tatcgaaaaa
    10261 gagtcggtta ttgaggccgg ttttcacgtc ctgggcggca taagagcgga tcagcgtatc
    10321 aagacggctg tgttgttcgc gtgcgttctg aatttcacga agcagcgtat ccagcgcact
    10381 gctggttctg ggcggccatt catagatggt tcccaacaca ttagagccac gctcaccgtt
    10441 taagatacga gtagcccggg tttccagcaa ttcttgcccg gcaagttgcc gttgtaacca
    10501 gcgtaccgcc aggaagagca taacaatgat aaagccaatc gcccccgtga gcggcgcggt
    10561 ggtcatcaac gaatggaaat agttgcccat cggatcctga taaaccagac gcaacgacat
    10621 ccccggatgc tttatcaacg gaacgctcag ttcgcgaaac agatcgctgg agccaactgg
    10681 acgataacta ccatttctgg ccagggtata aacctgttta tcaccatgga gcaggtctac
    10741 acgaacgata tctgccgaca tcattaattc ggtaatttgt ggccttaata cgctgaagtc
    10801 attcgacaca aggtgggtat caatcgccgt cgccaccgcc tgaacgcgat gactaaactt
    10861 atactgaatg gcgttgtaga aacttagcga acagcccagc aaagtcacaa aaattgttaa
    10921 cccggtgagc agcgtaacaa aggccgaaaa tttcgtcgtt aatctcatcc ttgtgttaac
    10981 tccgatagtg aggaagcggg catactagca aatcagattt atctcgcaat ttattgcgct
    11041 tcatcggctt tgcttttcca ttagcgagta tagtcttcag aaattatttt ccaatccatc
    11101 atgcacatga ggaccactta tgcaggcgtt acttttagaa cagcaggacg gcaaaactct
    11161 cgcatcagta cagactctgg acgaaagtcg cctgccggag ggcgatgtca cggtcgatgt
    11221 tcactggtcg agcctgaact ataaagatgc gctggcgatt accggtaagg gaaaaatcat
    11281 ccgtaatttt ccgatgattc ctgggatcga ttttgccgga actgtacgca ccagcgaaga
    11341 tccgcgtttt catgccggtc aggaggtgtt actcactggc tggggcgttg gtgaaaacca
    11401 ctggggtggg ctggcggagc aggcgcgagt gaaaggtgac tggctggttg ccatgccgca
    11461 agggctggac gcgcgtaaag caatgattat cggtactgcc ggttttaccg ccatgctgtg
    11521 tgtgatggcg ctggaagatg ccggtgttcg cccgcaggac ggggagattg tcgtgacggg
    11581 tgccagtggt ggcgtcggca gtaccgccgt ggcgctgctg cataagttgg gttatcaggt
    11641 cgttgccgtt tccggtcgcg aaagtaccca tgaatatctg aaaagtttag gtgctagccg
    11701 tgttctccct cgtgatgagt ttgccgaatc ccgtcctctg gaaaaacaag tctgggctgg
    11761 ggcaattgac accgttggcg acaaagtgct ggcaaaagtg ctggcgcaaa tgaattacgg
    11821 cggctgcgtg gcggcctgtg gtctggcggg tggttttact ctgccaacca cggtcatgcc
    11881 atttattctg cgtaatgtcc gtttgcaagg ggtggattca gtaatgacgc caccagaacg
    11941 ccgcgcacaa gcctggcagc gactggtcgc cgatttaccg gaatcattct atacccaggc
    12001 ggcaaaagag atatctctgt cagaggcacc gaactttgcc gaggccatca ttaataacca
    12061 gatccagggt cgcacgctgg tgaaggttaa ctaaccattt agcagggaat aataagagag
    12121 ggaactcatt ttgaaatcat tattcaatcg gttaacggga aaagcggtta gccggacagc
    12181 tttcgtcgaa caccttggtc aggaagttat acaacatcat ccaaactgga aagtcatgat
    12241 ttcgactgac cacaaattga tgcgcattga tactccacta aacagctatt attgatacgc
    12301 ctccgtcgcc tgttaggttt atggtgcttt gcctgggcga cgctacgctt agccccttac
    12361 ttatttctgg taccatgggg tgaataatct gattttgttt gactacaaat taatcactcg
    12421 aacctattta atgctgagca ttgtcaatcg gttaattttg cgtgctttag cattcacatc
    12481 tatccagacg atgcagtgaa aattgggtaa tccccagcaa ccgctgcgta atgtcgtcta
    12541 tcttgtcgcg atcctggcat ccctacatta tttgtggtct gtgaagatta tctcattgca
    12601 gcccctcatc ttcgcagggc tggcttttca gcttttcacc ttacgttata agaagttccg
    12661 tcgatgatgg cgctaatttc gtgaattgtg cggcttgttg caaattacac ggtgttgaag
    12721 gttatttaca tgttagctgt tgattatctt ccctgataag accagtattt agctgccaat
    12781 tgctacgaaa tcgttataat gtgcgacctc gtcctccctg acgcagtttt tgcgctgcgg
    12841 aaaaggtgac attggcgcaa cgaaggtata ttttgttttt tgccggagga tagcagcaga
    12901 tcgctgcaca atgtccgtca agtctaacat tgacactctg gggcaaaata gaccggcgtc
    12961 ccggcctgct ggaatttatc gctatgcata cagctgtcgg ggcatacgct ttacagacgg
    13021 cggtgaaacg cctgtcacaa tcacactaaa caaagagtac ggaacccact catggatatt
    13081 cgtaagatta aaaaactgat cgagctggtt gaagaatcag gcatctccga actggaaatt
    13141 tctgaaggcg aagagtcagt acgcattagc cgtgcagctc ctgccgcaag tttccctgtg
    13201 atgcaacaag cttacgctgc accaatgatg cagcagccag ctcaatctaa cgcagccgct
    13261 ccggcgaccg ttccttccat ggaagcgcca gcagcagcgg aaatcagtgg tcacatcgta
    13321 cgttccccga tggttggtac tttctaccgc accccaagcc cggacgcaaa agcgttcatc
    13381 gaagtgggtc agaaagtcaa cgtgggcgat accctgtgca tcgttgaagc catgaaaatg
    13441 atgaaccaga tcgaagcgga caaatccggt accgtgaaag caattctggt cgaaagtgga
    13501 caaccggtag aatttgacga gccgctggtc gtcatcgagt aacgaggcga acatgctgga
    13561 taaaattgtt attgccaacc gcggcgagat tgcattgcgt attcttcgtg cctgtaaaga
    13621 actgggcatc aagactgtcg ctgtgcactc cagcgcggat cgcgatctaa aacacgtatt
    13681 actggcagat gaaacggtct gtattggccc tgctccgtca gtaaaaagtt atctgaacat
    13741 cccggcaatc atcagcgccg ctgaaatcac cggcgcagta gcaatccatc cgggttacgg
    13801 cttcctctcc gagaacgcca actttgccga gcaggttgaa cgctccggct ttatcttcat
    13861 tggcccgaaa gcagaaacca ttcgcctgat gggcgacaaa gtatccgcaa tcgcggcgat
    13921 gaaaaaagcg ggcgtccctt gcgtaccggg ttctgacggc ccgctgggcg acgatatgga
    13981 taaaaaccgt gccattgcta aacgcattgg ttatccggtg attatcaaag cctccggcgg
    14041 cggcggcggt cgcggtatgc gcgtagtgcg cggcgacgct gaactggcac aatccatctc
    14101 catgacccgt gcggaagcga aagctgcttt cagcaacgat atggtttaca tggagaaata
    14161 cctggaaaat cctcgccacg tcgagattca ggtactggct gacggtcagg gcaacgctat
    14221 ctatctggcg gaacgtgact gctccatgca acgccgccac cagaaagtgg tcgaagaagc
    14281 gccagcaccg ggcattaccc cggagctgcg tcgctacatc ggcgaacgtt gcgctaaagc
    14341 gtgtgttgat atcggctatc gcggtgcagg tactttcgag ttcctgttcg aaaacggcga
    14401 gttctatttc atcgaaatga acacccgtat tcaggtagaa cacccggtta cagaaatgat
    14461 caccggcgtt gacctgatca aagaacagct gcgtatcgct gccggtcaac cgctgtcgat
    14521 caagcaagaa gaagttcacg ttcgcggcca tgcggtggaa tgtcgtatca acgccgaaga
    14581 tccgaacacc ttcctgccaa gtccgggcaa aatcacccgt ttccacgcac ctggcggttt
    14641 tggcgtacgt tgggagtctc atatctacgc gggctacacc gtaccgccgt actatgactc
    14701 aatgatcggt aagctgattt gctacggtga aaaccgtgac gtggcgattg cccgcatgaa
    14761 gaatgcgctg caggagctga tcatcgacgg tatcaaaacc aacgttgatc tgcagatccg
    14821 catcatgaat gacgagaact tccagcatgg tggcactaac atccactatc tggagaaaaa
    14881 actcggtctt caggaaaaat aagactgcta aagcgtcaaa aggccggatt ttccggcctt
    14941 ttttattact ggggatcgac aacccccata aggtacaatc cccgctttct tcacccatca
    15001 gggacaaaaa atggacactc gttttgttca ggcccataaa gaggcgcgct gggcgctggg
    15061 gctgaccctt ttgtatctgg cagtttggtt agtagccgct tacttatctg gcgttgcccc
    15121 cggttttacc ggctttccgc gctggtttga gatggcctgc atcctgacgc cgctgctgtt
    15181 tattggactg tgctgggcga tggtgaaatt tatctatcgc gatatcccac tggaggatga
    15241 cgatgcagct tgaagtaatt ctaccgctgg tcgcctatct ggtggtggtg ttcggtatct
    15301 cggtttatgc gatgcgtaaa cggagcaccg gcaccttcct taatgagtat ttcctcggca
    15361 gccgctctat gggcggtatt gtgctggcga tgacgctcac cgcgacctat atcagtgcca
    15421 gttcgtttat cggcgggcca ggagctgctt ataaatacgg gctgggctgg gtattgctgg
    15481 cgatgattca gcttcctgca gtctggcttt cactcggtat tctcggcaag aagtttgcga
    15541 ttcttgcgcg ccgctacaat gcagtgacgc taaacgatat gctgtttgcc cgctaccaga
    15601 gtcgtcttct ggtgtggctg gcgagtttga gtttgctggt tgcgttcgtt ggtgcgatga
    15661 ccgtgcagtt tatcggcggt gcgcgcctgc tggaaaccgc ggcgggtatt ccttatgaaa
    15721 ccgggctgct gatttttggt atcagcattg cgttatatac cgcctttggt ggctttcgcg
    15781 ccagcgtgct gaacgacacc atgcaagggc ttgtgatgct gattggcacc gttgtgctgc
    15841 ttattggcgt ggtacatgcc gctggcggct taagcaacgc agtacagacc ttgcaaacca
    15901 tcgatccgca actggttacg ccacaaggcg ctgacgatat tctgtcgcct gcctttatga
    15961 cgtcgttctg ggtactggtg tgctttggcg ttataggcct gccgcatact gcggtgcgct
    16021 gtatctctta taaagacagc aaagcagtac accgggggat catcatcggt acgattgtag
    16081 tcgcaatcct gatgttcggt atgcacctgg ccggagcgtt aggtcgggcg gtgatccccg
    16141 atctcaccgt accggatctg gtgatcccga cgttaatggt aaaagtgctg ccaccgtttg
    16201 ccgccgggat cttcctggct gcaccgatgg ctgcgatcat gtcgacaatt aacgcccaac
    16261 tgctgcaaag ttccgctacg atcattaaag atctctatct gaatatccgt ccggatcaaa
    16321 tgcaaaacga gacgcgtctg aagcggatgt cggcggtaat tacgttagtt ctcggcgcgt
    16381 tgctgctgct tgccgcctgg aagccgccag aaatgatcat ctggctgaat ttgctggcct
    16441 tcggtgggct ggaagccgtt ttcctgtggc cgctggtgct gggtctttac tgggaacgcg
    16501 ccaacgccaa aggcgcgcta agtgcgatga tcgttggcgg cgtgctgtat gccgtactcg
    16561 cgacgctgaa tattcagtac ctgggcttcc accctatcgt gccctcgtta ctactaagtt
    16621 tgctggcttt cctggtcgga aaccgtttcg gtacatccgt cccgcaagct accgttttga
    16681 ctactgataa ataaagagtt ttgccatgcc ttggatccaa ctgaaactga acaccaccgg
    16741 cgcgaacgcg gaagatctta gcgatgcgct gatggaagcg ggtgccgttt ctatcacttt
    16801 tcaggatacc cacgatacgc cagtatttga gccgctgccg ggcgaaacgc gcctgtgggg
    16861 cgacaccgat gtgattggtc tgttcgacgc tgaaaccgat atgaacgacg tggtggcgat
    16921 tctggaaaac catccgctgc tcggcgcagg cttcgcgcat aaaatcgaac aactagaaga
    16981 taaagactgg gagcgcgaat ggatggataa tttccacccg atgcgctttg gtgaacgact
    17041 gtggatctgc cctagctggc gtgatgtgcc ggacgaaaac gccgtcaacg tgatgttaga
    17101 tccagggctg gcgtttggta cgggtaccca tccaaccacc tctctgtgcc tgcaatggct
    17161 cgacagcctc gatttaaccg gtaaaacagt catcgacttt ggctgtggtt ccggcattct
    17221 ggcgatcgcg gcgctgaaac tgggtgcagc aaaagccatt ggtattgata tcgatccgca
    17281 ggcgattcag gccagccgcg ataacgccga acgtaatggc gtttctgacc gtctggaact
    17341 ctacttaccg aaagatcagc cagaagaaat gaaagccgac gtggtggtcg ctaacatcct
    17401 tgcaggccca ttacgtgaac tggcaccgtt aatcagcgtc ctgccggttt caggcggttt
    17461 gctgggcctt tccggtattc tggcaagcca ggcagagagc gtttgtgaag cttatgccga
    17521 tagcttcgca ctggacccgg tcgtggaaaa agaagagtgg tgccgtatta ccggtcgtaa
    17581 gaattaacct tcgcatcgcc gtagggtgac gcggggcgaa gtgcgagcaa gctcacaaaa
    17641 ggcacgtaaa tttgccgatt atttacgcaa atttgcgtgc caaaattttc attcataaag
    17701 aaaaattgag aacttactca aatttctttg agtgtaaatt ttagtcacta ttttctaata
    17761 tgatgatttt tatgagtaat tatcgcacca cgctcatttt aaatgcaatt ctttgatcca
    17821 tctcagagga ttggtcaaag tttggccttt catctcgtgc aaaaaatgcg taatatacgc
    17881 cgccttgcag tcacagtatg gtcatttctt aactcatgcg catcggacaa tatcagctca
    17941 gaaatcgcct gatcgcagcg cccatggctg gcattacaga cagacctttt cggacgttgt
    18001 gctacgagat gggagccgga ttgacagtat ccgagatgat gtcttctaac ccacaggttt
    18061 gggaaagcga caaatctcgt ttacggatgg tgcacattga tgaacccggt attcgcaccg
    18121 tgcaaattgc tggtagcgat ccgaaagaaa tggcagatgc agcacgtatt aacgtggaaa
    18181 gcggtgccca gattattgat atcaatatgg gttgcccggc taaaaaagtg aatcgcaagc
    18241 tcgcaggttc agccctcttg cagtacccgg atgtcgttaa atcgatcctt accgaggtcg
    18301 tcaatgcagt ggacgttcct gttaccctga agattcgcac cggctgggca ccggaacacc
    18361 gtaactgcga agagattgcc caactggctg aagactgtgg cattcaggct ctgaccattc
    18421 atggccgtac acgcgcctgt ttgttcaatg gagaagctga gtacgacagt attcgggcag
    18481 ttaagcagaa agtttccatt ccggttatcg cgaatggcga cattactgac ccgcttaaag
    18541 ccagagctgt gctcgactat acaggggcgg atgccctgat gataggccgc gcagctcagg
    18601 gaagaccctg gatctttcgg gaaatccagc attatctgga cactggggag ttgctgcccc
    18661 cgctgccttt ggcagaggtt aagcgcttgc tttgcgcgca cgttcgggaa ctgcatgact
    18721 tttatggtcc ggcaaaaggg taccgaattg cacgtaaaca cgtttcctgg tatctccagg
    18781 aacacgctcc aaatgaccag tttcggcgca cattcaacgc cattgaggat gccagcgaac
    18841 agctggaggc gttggaggca tacttcgaaa attttgcgta aacagaaata aagagctgac
    18901 agaactatgt tcgaacaacg cgtaaattct gacgtactga ccgtttctac cgttaactct
    18961 caggatcagg taacccaaaa acccctgcgt gactcggtta aacaggcact gaagaactat
    19021 tttgctcaac tgaatggtca ggatgtgaat gacctctatg agctggtact ggctgaagta
    19081 gaacagcccc tgttggacat ggtgatgcaa tacacccgtg gtaaccagac ccgtgctgcg
    19141 ctgatgatgg gcatcaaccg tggtacgctg cgtaaaaaat tgaaaaaata cggcatgaac
    19201 taattcaggt tagctaaatg cttgattaaa aaggcgctac tcggcatggg gaagcgcctt
    19261 ttttataggt gtcacaaagg gagtgaccat gagaacagga tgtgaaccga cccggtttgg
    19321 taatgaagct aagaccatta ttcacggtga tgcgcttgcc gaacttaaaa agatccccgc
    19381 cgaaagtgtc gatctgatct ttgccgaccc accatataac atcggtaaaa attttgatgg
    19441 tctgatcgaa gcctggaaag aagatctgtt tatcgactgg ctgtttgaag tgattgcaga
    19501 gtgccaccgc gttctgaaaa agcagggcag catgtacatc atgaacagca cggaaaacat
    19561 gccctttatc gatctccagt gccgcaagct ttttaccatc aaaagtcgca tcgtctggtc
    19621 atatgacagt tctggagtac aggcgaaaaa acactacggc tccatgtacg aacccatcct
    19681 gatgatggtg aaagacgcaa agaactacac attcaacggt gatgctattc tggtagaagc
    19741 caaaaccgga tcgcagcgcg cgttgatcga ttatcgcaaa aatcctccac agccatacaa
    19801 tcatcaaaaa gtaccgggta acgtctggga ttttccgcgc gtgcgttatt tgatggatga
    19861 atatgagaac cacccgacgc aaaaaccgga agccttactg aaacgcatta ttctcgcctc
    19921 ttccaaccca ggcgatatcg ttctcgaccc gtttgccggt agctttacta ccggtgccgt
    19981 agccgtctcc agcgggcgaa aattcattgg tattgagatc aacagcgagt acatcaaaat
    20041 ggggcttcga cggctggatg tcgcgtcgca ttactctgcg gaagaactgg cgaaagtgaa
    20101 aaaaagaaag accggcaacc tgtcaaaacg aagccggtta agcgaagttg accccgatct
    20161 cattgcaaag taaaggaagt gtaagcctgg ttttcagatt attcatttcg tgtatatttc
    20221 ctgccagact tggttaaaca tgcacaggct caggtaatga ttcgcaagta ttggtggctc
    20281 gtcgttttcg ctgtcttcgt ttttctgttt gatactttac tgatgcagtg gattgaactg
    20341 ctgacaacag aaacagacaa atgccgtaat atgaactcag ttaatccact aaaactggtt
    20401 aactgtgacg aactgaattt tcaggacaga atgtgaattt acatgacact taattcattc
    20461 gtttgatgaa ttaatttcgt tatgttttca tctggcatga acattcttaa tacgttatcg
    20521 accagcgcgg gtgcttgttt ataaagatca taacccgcca tattcattaa ccagttttga
    20581 acaattccgc tgaaggcacc atcaataata atcatcacaa catctaaatc gaggttattt
    20641 gctacacaac cttgttgctg acacgcctgc aatacttcgc ggagagtctg cggattaaag
    20701 cccatctttt cgcgtatcac tacctcggcc agcatctcat cattaaattc acatttgtga
    20761 tataagattt tcagcaacgc ctgctggcgg ggaattttgg caatatattg caagccgaca
    20821 atcaattttt cacgcaattg ttgaaacggg tcatgctcta atccagccgt caagtgttcc
    20881 tggattaact cccgcaatga aggctgttgc aaccacatct cattaaacag ttgggtcttg
    20941 ttctcgaagt gccagtagat agcgccacgc gtaacgttag cggcatcggc aatgtcgttg
    21001 agcgtcgtct tgcttacgcc atgttgcgca aactgggcga tggcagtttc aatcagttct
    21061 tgccgggtct tcagagcttc ggctttggtt ctttttgcca tgattaatta ttcaggaaat
    21121 aaatatattc gacacagggt gagaaaatag cgaaggttaa tctatcatct aatgtgtatt
    21181 ta
//
LOCUS       DAPHKZ010000073        21079 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.073, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000073 DAPHKZ010000000
VERSION     DAPHKZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21079
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.073"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(32..1891)
                     /gene="gss"
                     /locus_tag="RH288_002886"
     CDS             complement(32..1891)
                     /gene="gss"
                     /locus_tag="RH288_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HDV4031926.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVF
                     RSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQ
                     AFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQ
                     WTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLEN
                     KGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLH
                     ATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNAD
                     SASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEE
                     NYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQ
                     IREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLF
                     PHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNI
                     YQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKK"
     gene            2096..2962
                     /gene="yghU"
                     /locus_tag="RH288_002887"
     CDS             2096..2962
                     /gene="yghU"
                     /locus_tag="RH288_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HDV4031927.1"
                     /translation="MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIP
                     ALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGG
                     FGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGN
                     VVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDAS
                     DFETNTEDKRQG"
     gene            complement(3085..3333)
                     /gene="hybG"
                     /locus_tag="RH288_002888"
     CDS             complement(3085..3333)
                     /gene="hybG"
                     /locus_tag="RH288_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HDV4031928.1"
                     /translation="MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADL
                     LGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA"
     gene            complement(3346..3687)
                     /gene="hypA"
                     /locus_tag="RH288_002889"
     CDS             complement(3346..3687)
                     /gene="hypA"
                     /locus_tag="RH288_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HDV4031929.1"
                     /translation="MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAV
                     RFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPLCHGERLRVDTG
                     DSLIVKSIEVE"
     gene            complement(3680..4168)
                     /gene="hybE"
                     /locus_tag="RH288_002890"
     CDS             complement(3680..4168)
                     /gene="hybE"
                     /locus_tag="RH288_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HDV4031930.1"
                     /translation="MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSD
                     FTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDGV
                     SQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGE
                     NA"
     gene            complement(4161..4655)
                     /locus_tag="RH288_002891"
     CDS             complement(4161..4655)
                     /locus_tag="RH288_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HDV4031931.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKNAPGTMMILRDEEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPRE
                     AIHD"
     gene            complement(4655..6358)
                     /gene="hybC"
                     /locus_tag="RH288_002892"
     CDS             complement(4655..6358)
                     /gene="hybC"
                     /locus_tag="RH288_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HDV4031932.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNL
                     AVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRG
                     KGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHS
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRE
                     STQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNI
                     GKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            complement(6355..7533)
                     /gene="hybB"
                     /locus_tag="RH288_002893"
     CDS             complement(6355..7533)
                     /gene="hybB"
                     /locus_tag="RH288_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HDV4031933.1"
                     /translation="MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLQRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAF
                     IMGFSIVIFEGSLVQAGLRGNGPDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLS
                     LAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALSALLGCATWRLTYSL
                     VAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            complement(7523..8509)
                     /gene="hybA"
                     /locus_tag="RH288_002894"
     CDS             complement(7523..8509)
                     /gene="hybA"
                     /locus_tag="RH288_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HDV4031934.1"
                     /translation="MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGGNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPK
                     LDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES"
     gene            complement(8512..9630)
                     /gene="hybO"
                     /locus_tag="RH288_002895"
     CDS             complement(8512..9630)
                     /gene="hybO"
                     /locus_tag="RH288_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HDV4031935.1"
                     /translation="MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVT
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSA
                     GAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            complement(9819..10106)
                     /locus_tag="RH288_002896"
     CDS             complement(9819..10106)
                     /locus_tag="RH288_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HDV4031936.1"
                     /translation="MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMY
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN"
     gene            complement(10225..11109)
                     /locus_tag="RH288_002897"
                     /pseudo
     CDS             complement(10225..11109)
                     /locus_tag="RH288_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311911.3"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
     gene            11266..12306
                     /gene="gpr"
                     /locus_tag="RH288_002898"
     CDS             11266..12306
                     /gene="gpr"
                     /locus_tag="RH288_002898"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HDV4031937.1"
                     /translation="MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALES
                     QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDM
                     WPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
                     KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVG
                     CIAFTPLAQGLLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQ
                     RGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTKELAQIDQHIAD
                     GELNLWQASSDK"
     gene            complement(12346..12840)
                     /locus_tag="RH288_002899"
     CDS             complement(12346..12840)
                     /locus_tag="RH288_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HDV4031938.1"
                     /translation="MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPN
                     IFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            13031..13915
                     /gene="yghA"
                     /locus_tag="RH288_002900"
     CDS             13031..13915
                     /gene="yghA"
                     /locus_tag="RH288_002900"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HDV4031939.1"
                     /translation="MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKA
                     VLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
                     VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(14187..14612)
                     /gene="exbD"
                     /locus_tag="RH288_002901"
     CDS             complement(14187..14612)
                     /gene="exbD"
                     /locus_tag="RH288_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HDV4031940.1"
                     /translation="MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTI
                     FFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK"
     gene            complement(14619..15353)
                     /gene="exbB"
                     /locus_tag="RH288_002902"
     CDS             complement(14619..15353)
                     /gene="exbB"
                     /locus_tag="RH288_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HDV4031941.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGSKSLSLHLLNEAQNELELSEGSD
                     DNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLL
                     LQSRDLDLEASAAAHPVRVAQKLRAG"
     gene            15605..16792
                     /gene="metC"
                     /locus_tag="RH288_002903"
     CDS             15605..16792
                     /gene="metC"
                     /locus_tag="RH288_002903"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HDV4031942.1"
                     /translation="MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGD
                     HVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSIT
                     MEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDA
                     MIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEW
                     LAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLF
                     SMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFA
                     RIV"
     gene            16932..17591
                     /locus_tag="RH288_002904"
     CDS             16932..17591
                     /locus_tag="RH288_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV4031943.1"
                     /translation="MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAASLGCWLSYIQGRWLGNTKTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
                     GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCN
                     A"
     gene            complement(17631..18530)
                     /gene="yqhC"
                     /locus_tag="RH288_002905"
     CDS             complement(17631..18530)
                     /gene="yqhC"
                     /locus_tag="RH288_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YqhC"
                     /protein_id="HDV4031944.1"
                     /translation="MKREEICRLLADKVNKLKNKENSLSELLPDVRLLYGETPFARTP
                     VMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLN
                     VDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMERPLDARILG
                     KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEAN
                     MSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRAMQGN"
     gene            18724..19887
                     /gene="yqhD"
                     /locus_tag="RH288_002906"
     CDS             18724..19887
                     /gene="yqhD"
                     /locus_tag="RH288_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDV4031945.1"
                     /translation="MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKT
                     GVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK
                     FIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE
                     GILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFF
                     EQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR"
     gene            19992..20819
                     /gene="dkgA"
                     /locus_tag="RH288_002907"
     CDS             19992..20819
                     /gene="dkgA"
                     /locus_tag="RH288_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
                     /protein_id="HDV4031946.1"
                     /translation="MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRS
                     IDTAAAYKNEEGVGKALKNASVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYID
                     LYLMHWPVPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
                     IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVI
                     RWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG"
BASE COUNT         5199 a         5662 c         5280 g         4938 t
ORIGIN      
        1 cataatcagt acggggttgc tacaacatgt attacttttt caccacaatt aacggttcaa
       61 tatcactctc ttttttgatg accagtgatt catcaccgcg caaacacgtc ccaccgtagt
      121 tgccgccaac ggtgaaggta catacctgaa tgtatttacc gtccactttc ggcaaacacc
      181 acagttgctg atagatgttt ttctgctcgg caaatttacc gctggttttg tccagcacct
      241 cttcatgatg gctgacgagg tcgatattgc tgccacagcg accggcgatc ggtttcactg
      301 cgtaacctgt tttcaccagt tcatcattaa cagtgaaatc ggtatccagc aggtaacgat
      361 ggtgcgggaa cagcgaccag aggatcggca gaatcgcttt gttgccgggg atcaccgtcc
      421 acagcggctc aaagaccagc acttccgggc gcagcaatac gtcgataaga cgcacttcgt
      481 tttgcggatg accggtacgg attggcaccg cagcaaactc acggtcgcta acttcacgaa
      541 tctgatcaaa cgcggtttcc cacgcccagg ttttccacac gcagttaacc agtcgccctt
      601 ccccatcaat cagttgcccg gcagcatccc agcccagttc atccaatcca cgcaagatac
      661 gcgtttcaaa gcccgcctgg tgcagcgcct gctccataaa ctgcgcgtga tagttttcct
      721 cgatatcttt gtcctgcatg atatggacaa acggacgtgc acgactgtgt ttccaggcac
      781 cagccaattc gttaatcagc ccttccgccg gattgaagcc gttgccttta tagccctgct
      841 ccgcccaacg ttcgaggatc aagcccgctt cggtatgaca ggaggcggag tcggcgttgt
      901 actcgtaaac cttcaggcca cgctcatcca tgcagaaatc catacgacca gtgatcatat
      961 ggtgacggcg acgctgccag gagagacgca aacgtggcca gaggattttc gggatgtcga
     1021 acagcgccag caggttgtca tctttcagca ccttgtcggt tgcgtgaaga tacatcaggt
     1081 gcagctcgtt ggtggcttta attagctcct gctcggcact ctcggtaatg gtgtagtaat
     1141 gataaggatc ctgattgatc acctgaccgt tggcctgcac ataggcgttt tgcagcggat
     1201 ctttttcatc cagccattta ccgtcaaact ggcctttgtt ttccaggcgc gctccgctga
     1261 ttttcagcag ctcgcctgca atttccggct gcggtaagct gtattcagta tcttccgtct
     1321 ggatcatcca gcccagaatg gtggtgtcat caaaagtgtc tttcagggta tagcagccgt
     1381 tttcgaccac catctccagc tcgcgcgtcc actgttgccc ttgcggcaac ggggaatgaa
     1441 tcacgttctg ttccgcaata cggactttgt tgccatgcaa ttgggtaatg atggcgacat
     1501 ggccagtgtc tttaaattca ccgcctttat cccagataag aagcgcaccc gcgaccggcg
     1561 cacgcggcga gccgttagga aatgcctgca atggcaggat gttgtcatta accacttctc
     1621 gcaggaagcg cagcgagaaa atctcccacg ccatacccac gtcagtaaag accacaccgt
     1681 aattcagaaa gagaaaacgg cgagcaaatt caacgcattg ccacttgtgg cccatatatt
     1741 cgtcgtcgat atagctacgg aatacggcgt catcttcgta ttcctgcgga tcgagagaac
     1801 tgtaatctga agagtagatt gctaccccac ctggggcgta gcccaataat gtcccgaacg
     1861 gggcatcctg gctggtcgtt cctttgctca tcactttacc tttaacaata caacctaagc
     1921 agttggcgta attgttgtgc tctgattacc tgctcagcga cattaaccgg acagaggtca
     1981 gactaatcat acacctcatc gcagcggctg gcgcaaaggg ttaaaaaatt cacattctgt
     2041 acagcaagtg acctgctaca ctgcttcaac actaccactc agaaggcaac tcactatgac
     2101 agacaatact tatcagcccg cgaaagtctg gacgtgggat aaatccgctg gcggcgcgtt
     2161 cgccaatatc aatcgcccgg tttctggtcc gacgcatgaa aaaacgctgc ccgttggcaa
     2221 acacccattg caactttatt cgctgggaac gccgaacggt cagaaagtaa cgattatgct
     2281 tgaggagctg ctggcgctgg gcgttactgg tgcagagtac gacgcctggc tgattcgtat
     2341 tggcgatggc gatcaattct ccagcggctt tgtcgaagtg aacccaaact cgaagatccc
     2401 ggcgctgcgc gatcatacgc ataatccgcc gatccgcgtg tttgaatctg gttcgatcct
     2461 gctttatctg gcggagaaat ttggctactt cctgccgcag gatttggcaa agcgtactga
     2521 aacgatgaac tggctgttct ggttacaggg cgcggcaccg ttcctcggcg gtggttttgg
     2581 tcacttttac cattacgcac cggtaaagat tgagtacgcc atcaaccgct ttaccatgga
     2641 agccaaacgt ctgctcgacg tgctggataa gcaactggcg cagcataagt ttgttgcggg
     2701 cgatgagtac accattgcgg atatggcgat ttggccgtgg tttggcaacg tggtgttagg
     2761 tggtgtgtat gatgccgctg agtttcttga tgcgggcagt tataagcatg tacaacgctg
     2821 ggcgaaagaa gtaggcgaac gtccggcggt gaaacgtggg cgtattgtta accgcaccaa
     2881 cggaccgctg aatgagcagt tgcatgagcg ccatgacgcc agtgatttcg agacgaatac
     2941 ggaagataag cgtcaggggt aagggttggt gttcgtcgca gcaagccatc caggccggat
     3001 aaggcgttca cgccgcatcc ggcaatcgtg cacaatgcct gatgcgacgc tgccgcgtct
     3061 tatcaggcct acgaaagcta atcatcacgc gctggtaatg tcgtaatcca tttggcgcag
     3121 tgcgtctaat gtggctttgg cttcatcttc gtcgatgatg ctcatggcaa atccgacgtg
     3181 taccagcacc cactggccca gtagatcggc agggttacct tcacaaatca gggcgatatt
     3241 cacatcgcgc ttgataccac atacttcaac ctgcgcaagc tggtgaatat cttcaccgac
     3301 agccagcacc tggcctggaa cgccaataca cattattaac tccggttatt caacttcaat
     3361 acttttgacg atcagcgaat cgccggtatc gacacgcaac cgctcgccgt gacagagcgg
     3421 acactgcgca tcgtgctgat gaatctccac cacctggctg caatcccagc accaagcctg
     3481 ggcgggttta tagacgatat gtaaatcgca cccttgcgcc accgttccgt ggcagacaat
     3541 ttcaaaacta aaacggacgg cgctctcctc aacgcaggag agcgcgccaa tttccagcca
     3601 cacggcggtg acgcgcttaa catcgtgctg ctccgcctgc cgttggataa tttcaacggc
     3661 gctctggcaa agagacaact catgcatttt cgccactcct gcgaccaaac agcagggcgc
     3721 gacgccctgc gtgtggtaca tccggattcg tgactggcag cgaaaggatc attcgtgcgc
     3781 agtcatccgt caggcgttgg ccctcttcaa tcgacatgct gtgcgaaagc ggcgacatca
     3841 gcgaacagga gagatattgc gaaacaccgt ccagttcgcc aacggtaaag gtcatagtgc
     3901 catacggcag ttgcagacca attttttcac tcactttgcg cagcggccag agttgatccg
     3961 ggccggggaa gataactgca ctcagcatcc acggggtgat cacacacccc gtccactgac
     4021 cttcgaacag cgtaaaatca gaaacataca ccggcattga aggatgcaga aaagagagat
     4081 cgtgcatcga acgccgggca atttcttcaa acgctgcctg tacttgcgcc ttcggggagg
     4141 tctggaaacc tgctatctct tcagtcatga atcgcctccc gtgggatggc ttccacgcca
     4201 gattcacgca gcgcagccag aacctgctca agcgcaggtt caatcattgc ttcaaccgtc
     4261 ggcgttaagc cgatgtgtgg ctccagcgat tccgggatca cgccgaccag ggtcagcttt
     4321 ttcggaaact cgccggtgaa gcgcagggcc gacaagacgt cggccaggcc aagctgatgc
     4381 ggagagattt tgttggtaaa caacgccgga acttcttcat cccgcaggat catcatcgtt
     4441 cccggcgcgt tctttttcga gacaatggca tccgcaataa tcaaatgatc gcgatttgcc
     4501 atgtcgccaa gcagctccat tcccgccgtg ccgccatcga ggatctcaac ataatccggc
     4561 agaatgtatc gttgctctaa cgcttcgaca atccgcacac cgatggcttc atcggtcagc
     4621 aaaatattgc cgacccctaa gactaaaata cgcattacag aaccttcact gaaaccactt
     4681 cgttgccgtc agcatccact acgtgtaccg cacaggccat gcacgggtca aaggagtgaa
     4741 tggtacgcac cacttccagc ggtttattcg gatcggcaac cggtgtaccc accagcgact
     4801 gctcgtaagg accgacgtca tcattgaagt tacgcggacc agagttccag gttgatggaa
     4861 caaccgcctg gtagttgctg atgataccgt ctttaataac catccagtga gagagcatac
     4921 cgcgcggcgc ttcgaggaag ccaacacctt tgaattcacc cgttgccgga atgttcggct
     4981 tcacaaaggt ggtgtgatcg cctttgccga tattggtgat cagtgcactg tattggtttt
     5041 gcaggatatc ctgcaattca cagcagtgaa cggtacgacc aataatacgg cccagcgtgg
     5101 agtgcagctg tgccacttcc agcgtgttgc cagtcagttt ctgataaatc gcaacgattt
     5161 cattcagttt gttctgggta gattcgcgac ctgccgccag tttcaccagc atattagcca
     5221 gtggccccac ttctaccgtt ttgccgtaga aagtcggtga tttcacccag gaatatttcc
     5281 cgtcgtcaga ccaaccatca taagccggaa tggtggtgcc ttcccacggt gcctgcggcg
     5341 cttcgtcttt ataccaggag tgcttcgcgc tttcctgaat gcctttgatc aggtattcat
     5401 cggaatgaga agtgatcgga cgatacgagg acagatccgc attctcaatg tagccgcccg
     5461 ggaacaggaa gctgccgttt ttactgtcgg tcgggaattc cggcacgctc aggtagttca
     5521 ccgcaccttt accgcgtgtc agccattccg ggtagaacgc ggcaataact gcggtatcaa
     5581 ccttataaac ctgctcaaca aagtcgctca gtttgtcgat gaaagacttg atgtacatca
     5641 ggcgctcaag gttcagcacg cccaaaccgt cgaggttgat cgggttcgcg acaccaccta
     5701 ccgccaggtt ctgaatgtgc ggcgttttac cgcccagcag cgccacgacg cggttagcgt
     5761 cacgctggca ctccaacgct tgcaggtagt gcgctaccgc aatcaggttc acttccggcg
     5821 gcagtttcat cgccggatga ccccagtagc cattagcgaa aatacccaac tgaccgctgg
     5881 caaccagatc tttgatcttg ttctgaactt tggtgaactc ttccggactg ttcaggtgcc
     5941 aggtcgaaac gcctttcagc atttcggagg ctttggttgg gtcagcttgc agtgcagaag
     6001 tgatgtccac ccagtccagc gccgaaagct gatagaaatg aacaatatgg tcatgcgtgg
     6061 tgtgcgcagc cagaatgatg ttacggatgt attgcgcgtt aaccggaacg tcgatattca
     6121 gcgcactttc tgccgcacga acggaagaca gcgcgtgagt ggtagtacat acgccacaga
     6181 tacgttgcac aatcatccat gcatcgcgcg gatcgcggtt tttcacgatc tcttccatgc
     6241 cgcgccacat ggtaccggaa gcccatgctt tcgaaacgac gccattttcg atttcgcaat
     6301 cgatgcgtaa atgcccctca atacgggtta ccggatcaat agtaattctc tggctcatgc
     6361 tttgctcgcc tcatgacgat tatgatcgtt ttgttttaaa ggaggaagta tcggcagtag
     6421 acgaatgagt acgatgtaag cgcaaatctc aatagccaca aaaccaatag aaatcaacag
     6481 ttcttcccag gtcgggaagt aggcgtaacc gccgcccggg ttgaatgcca ccagcgaata
     6541 ggtcagacgc caggttgcac aacctaacag tgcgctcagt gctgacagga acagcatgcg
     6601 ggaatcatta cgcagcttcg ccacacgcag aacgaccagc gggaagagca tcagcaggac
     6661 ttcaatccag aacatcacgg agtagaagtc accggcaaac gctaacgaca gcttgtcgcg
     6721 atagataagc tcgccaaagc gcagcacgat gaaaatcgcc agcaacacac tgatggtgtt
     6781 ggtcagctta acaaacagac tcttttcatc cggaccgttg ccacgcagac ccgcctgcac
     6841 cagcgaacct tcaaagatga caatcgagaa gcccatgatg aacgccgtca gcagcgagaa
     6901 cagcggcaac atttcatagc tctgccacaa cggatgcacc ttgtagcccg ccgagatcat
     6961 cagcgacccc attgaagact ggtgcatggt cggcagcagc gcaccgagcg cgatgatgaa
     7021 gaacatcacc ttgtttagtc gctgtagcga caccttccac cccagacgtt caaacagtgc
     7081 cggagcaaac tccagtgcca tcacgccgat atagatggtc atacagaccg ccgtctcgaa
     7141 cagtaccgag ttcacgttga agtgacccgg aatgtagaag tacggcaggt tccagtagcg
     7201 acccacgtcg atagtgatcg acaagccacc cagtgagtaa ccaaacagac tcgccaacag
     7261 cgccggacgc accagcggat ggtattgccc acggttaaag acgtataccg cccacgccag
     7321 cgcccagccg ccacaggcaa agccggtgcc aatcagcagg tcaaacgcga tccacacgcc
     7381 ccacgggaag ccgccgttca ggtcagagac agagcccaga ccgaacacca gacgcttcac
     7441 aatcaggagc atacagatga cgattaacgg tccaaaaatc atgaccggtt tactgatgat
     7501 tttgccgccc agcggttgtg gatcatgact catgatcgtc tcctccgtcg tgatggtcgt
     7561 ttttggtgtt gcgacgaacc agcacggtta agcccgccag cacagccagt ggtagcatca
     7621 tgcctttata cagggtgtgt tgaatatttt cggaacgcgc accggtagaa agatcgtcca
     7681 gtttcggcag gtcgagattt tcataaggca cacccgtcag taccagaacc tgagtaccgc
     7741 cgccctcttt ctcgccgtac agatgcggat aatatttcgg caccgtatgc aggtaagtgt
     7801 cgccagattt cagcgtctga cgcggatagt ggtattcgct gccaggcttc agcgccagac
     7861 gttttttcgc ctccgccatc agctcttcac gcgtaccgaa aatcaccgcg cccgccgggc
     7921 acacttctac gcagccaggt agaccgcctt tatcgagacg ttccacacct ttctggttgc
     7981 acagctcgca cttatgcagc gcaccaaacg ggttgttgta gtcgtacttc ggcacgttgt
     8041 acggacaggc gaccatgcag taacggcagc cggtgcacac atctttgtcg taatggacaa
     8101 tgccggtttt cggatctttt ttcagtgcag agaccgggca cacagagaca cagttcggat
     8161 cgacgcagtg catacactgt ttcttaatgt acgcgtagcc gttctcctcc tggtctttgt
     8221 tgccccctgt gccgctggtc cacacctgaa tgatgttatt ggtatacggc gacagtttgt
     8281 cgttgttcga ccaggtctgt tccccttgcg ggttacgttc agggaaattg atatcctgac
     8341 acttggtgac gcaagcctgg cagcctacgc acaaggtcga gtcgtacaac atccccagcg
     8401 atcccggaat tggcgggcgg ttttcagcag ccgcatgact gacagacggc agcgcgcccg
     8461 tcagcaatgc cccgcaggag gctgctttaa taaaattacg tctgttcacg gttattctcc
     8521 ccgtgagtca gcgttatctt tcttttgctg acgacccagt tcacgcaccg ccatcacgct
     8581 gacaccggca accaacccaa ccacaccgcc gagcaaacca atagcgcctg cagagacgtt
     8641 gccgccctct ttagcgttaa catccggttt ctgtgaacgc ggagtttgat tttcgacgtt
     8701 ggcaagctga tggatgcctt tatggaagcc gataccttct tcgttacagc catagcacgg
     8761 gtgaccaatc gccaccggcc acacaccgcc aacatcgcag aattgcagcg ttgagcagtt
     8821 gccgtaagtt tctggccctt tacagccgag gtggtacagg caccagcctt cgcggtggcc
     8881 ttcatcaccg aactctttgg caaaacgacc agcatcgaag tgcgggcgac gttcgcagtg
     8941 ttcgtgaatc agacggccat aggcgaaggt cggacggttt ttgtcatcca gtttcggcgg
     9001 tttgccgtaa gtgatgatgt gcgcaacggt cgcgaggaag ttgtgcgggt tcggcgggca
     9061 gcccggaata ttgataacgg ttttgcctgg cagaacttct tgcaggctga ctgcgccagt
     9121 tgggttaact ccagctgcgg caacaccgcc ccacgcagag caggaaccga tagcgataat
     9181 ggctgctgcg ccttccgccg ctttgcggat gtgatccaca atcggctcac cggcaaccat
     9241 gcaataaata ccgttatctt ttaatgggat ggaaccatcc accactaaca catactgccc
     9301 tttgtacttc tcgagagcgt tatgtttgtt ctcttcgacc tgatgaccga aggcggcgga
     9361 aagcacttcg tgatactcca gagagatagt ctccagtacg aggttttcta ccgttggatg
     9421 cgttgcacga agcagagatt ccgtacaacc ggtgcactcc tgcgcgccaa tccagataac
     9481 tggcggacgc tgcgggttag taaccgattc ggccatctct gcagcggctt tgctacttaa
     9541 ccccatggtg gcggctaatg ctgcacaaag cttcatgaaa tcacgacggt taatgccgtg
     9601 agaatggatg agggtgttat ctccagtcat ttatagttat tccgttgcga agacctggca
     9661 tatattttgc ctcaatcgca aaatcaataa tgcgatcgat gcgccattta ccacacattt
     9721 attatggtta tcgatatcat gatactgcgg cggggcgcta aaacgaaggg aagaagcatt
     9781 agtgtaatta attaaagcaa gataatacgt atgtttgatc aattttcgag gcgataaccg
     9841 gccataaaaa agcgcaacgt agaacaggaa ttattctcac gaaagaaatc cattaccatc
     9901 tctttatcca gtccatagcg gcgcgtcaga atacccgctt cccaggcgct aagctggcga
     9961 tctccggtct tttcgtacat ccggtgtgag tagcctaata caaaaccgcg tttataatcg
    10021 gcacagaatt ttgtcacatt aaccgcactg tcggcatgcg ttgcttttaa tcccgccatt
    10081 aagcctttac caaaatggtt attcatcgtt cacctcattc gctatatatt gtcatatata
    10141 gcgatatttt aggcaaagaa cgacttttgc gcacgctatt ttttcatgct tgtttaagac
    10201 gtaatcccgt aagagataaa cctatcagga gagatattta tcgaaccatt tcagtgtcct
    10261 ttgccaggca agatcggcgg cagatttgtc ataacggggc gtggaatcat tatggaatcc
    10321 gtgattaacc cccggataga tatacgcctc ataaacctta ttattggctt tcaacgccgc
    10381 ctcgtaagca ggccagccct cgttgattcg ggtgtccagt tccgcgaagt ggagtagtaa
    10441 aggcgcttca atcttcgcca catcggcagt gggtgcctga cgaccataaa acggcaccgc
    10501 gcaggccagt tccggatacg cgacagccgc cgcgttcgat acgccaccgc catagcaaaa
    10561 tccggtaata cccactttgc ctgtcgcttg cggatagcgt tgcataaact caattgcggc
    10621 aaagaaatca ttcatcagtt tgttggatca acctgctgtt gcagctcacg acctttatca
    10681 tcatttcccg gataacctcc aacggaactt aagccgtcag gtgccagggc gatatacccc
    10741 gccttcgcca ctcgccgtgc cacatcttcg atatacggat tcagtccacg attctcatgc
    10801 accaccacta cggctggcgt tttgccgctc atctttgcgg gcttcaccag ataaccccgc
    10861 acctcgccgt gaccatttgg cgaaggatac gtgatgtact cagcaacaat ttccgggtcg
    10921 gtaaactcta cctgagtcgc cagcgcataa tttggcttga gcaaatcaaa caacgctaat
    10981 gccgtcatcc cgcctaccgc acttcgccgc aaggttgagg aactcacgtt tcgagatttt
    11041 cccgtgagcg taatagtcat agtaatccag caactcttat gggaaatctt tggcggttaa
    11101 acgcggcatc gttgcactcc tcagttggtg tttttttaag caaagcataa gcacgtgttt
    11161 ttgcccagtt tttcgtcact ctgtgagcca gactacggga tacgcgctgg cgaatcgcta
    11221 aactagaaac attgtttcga aattgaacgg tggaaaggag aggtcatggt ctggttagcg
    11281 aatcccgaac gttacgggca gatgcaatac cgctattgcg gaaaaagtgg tttacgcctg
    11341 cccgcgttat cgctcggttt atggcacaat ttcggtcacg ttaacgcgct ggaatcacag
    11401 cgtgcgatcc tgcgtaaagc gtttgatttg ggcattacgc actttgattt agccaacaat
    11461 tacgggccgc ctccaggaag cgcagaagag aactttggtc gcctgctgcg ggaggatttt
    11521 gccgcttatc gcgatgaact gattatctct accaaggctg gctacgatat gtggcccggc
    11581 ccttacggct ctggcggttc acgtaaatac ctgctcgcca gcctcgacca aagcctgaag
    11641 cgtatggggc ttgagtatgt cgatatcttt tactctcatc gcgtcgatga aaatacgccg
    11701 atggaagaaa ccgcctctgc gctggctcat gcggtacaaa gcggtaaggc gctgtatgtc
    11761 gggatctcct cttactcgcc agagcggacg caaaaaatgg tcgagttgct gcgcgagtgg
    11821 aaaattccgc tgttaattca tcaaccttcg tacaatttac tgaaccgctg ggtggataaa
    11881 agcggcctgc tggataccct gcaaaataac ggcgtgggct gtattgcctt tactcctctg
    11941 gctcagggat tgctgaccgg aaaatatctc aacggcattc cgcaagattc acggatgcat
    12001 cgtgaaggga ataaagttcg tggtctgaca ccgaaaatgc ttaccgaagc caacctcaac
    12061 agcctgcgct tattgaatga aatggcacag cagcgtggac aatcaatggc gcaaatggcg
    12121 ttaagctggt tgctgaaaga tgatcgcgtg acgtcggtat tgattggtgc cagccgcgcg
    12181 gagcaactag aggagaacgt gcaggcgctg aataatctga catttagcac caaggagctg
    12241 gcgcagattg atcagcatat cgccgatggc gagctgaatc tgtggcaggc gtcttccgat
    12301 aaatgacctg ttaataacgg gcgcgcgaac cgcgcccgaa tcagatcagt gattatgacg
    12361 agtcagtcgg tcaagatagc ccatcacaaa tgcagaaagc acaaacgtca gatggataat
    12421 gacgtaccac atcagtttgt tatccgggac atttttcgca tccataaaga cgcgcagtaa
    12481 gtgaatggaa gaaattgcca caatcgacgc tgctactttg tttttcagcg acgttgcgtc
    12541 cattttcccc agccagttca gcttctcttt gttctcggag atatccagct gtgagacgaa
    12601 attctcataa ccggaaaaca tcaccatcac cagcaaaccg ccaaccagcg tcatatccac
    12661 cagcgacagc aacacgagga tcaaatctga ttccgccatc gagaagatat tcggcagtac
    12721 gtgaataatc tcctggaaga acttcagcgc cagggcaact aacgccagcg aaaggccaaa
    12781 gtacacgggg gcaagcagcc agcgagaagc atacattgca ttttcaagaa aacgttccat
    12841 acattcctgt cgtgtagtta aaacgggcaa cagtatatcg caattgagta aacagcacgc
    12901 aacagcaaat caacatatac gttaaacctt tgtcgcataa ttctgaggtt tagggatctt
    12961 cctggttccc ttatcaacgc atcgagaacg tctaccctta aaggacgttg aacctgaagg
    13021 gagaaaaacg atgtctcatt taaaagaccc gaccacgcag tattacactg gtgaatatcc
    13081 caaacagaaa caaccgacgc caggcatcca ggcgaagatg acaccggtac cggattgcgg
    13141 cgagaaaacc tatgttggta gcggtcgcct gaaagatcgt aaagcactgg tgacaggggg
    13201 cgattccgga ataggtcgcg ctgccgccat cgcttacgcg cgtgaagggg ctgacgtggc
    13261 gatcagttat cttcccgtgg aagaagaaga cgctcaggat gtgaaaaaga tcattgaaga
    13321 atgcggacgc aaagccgttc tgctgccagg cgatttaagc gatgagaaat ttgcccgttc
    13381 gctggttcac gaagcgcaca aggcgttagg cgggctggat attatggcgc tggtcgccgg
    13441 gaaacaggtt gccattccgg atattgcaga cctcaccagc gaacagtttc aaaagacctt
    13501 tgccattaac gttttcgcgc tgttctggct aacccaggaa gcgatccccc tgctaccgaa
    13561 aggtgcaagt atcatcacca cttcgtcaat ccaggcatac cagccaagtc cgcatttact
    13621 ggactatgcg gctacgaagg cggcgattct gaactacagc cgtggcttgg caaaacaggt
    13681 cgcggagaaa ggtattcggg tgaatattgt cgcgccaggc ccgatctgga cagcactgca
    13741 aatttccggc ggacaaacgc aggataagat cccgcagttt ggtcagcaaa cgccgatgaa
    13801 acgtgcgggg caaccggcgg aactggcccc tgtatatgtt tatctggcaa gtcaggagtc
    13861 gagctacgtc accgcagaag tgcacggcgt gtgcggcggc gagcatttag gttaaaaaaa
    13921 tgcccggttg tgaaaagcaa ccgggcatca ttgtgaattc actcttacct gatgtggcga
    13981 aaacgcctta tccgcctaca aacgcatgaa gattcaacat gttgcaatag attttgtagg
    14041 cctgataagc gtagcgcatc aggcattgag cacctaatgc cggatgcgtc gtgaacgcct
    14101 tatccggcct acaaacgcac gaagattcaa catgttgcaa tagattttgt aggcctgatg
    14161 agcgtagcgc atcaggcaat tctactttac ttcgctttgg cggtttcttc gccgaccaga
    14221 cctatcttca ggtaacccgc ctgatgcagc gtatccatta ccttcatcaa cgtctcgtaa
    14281 tcgacggttt tgtccgctcg gaagaagatg gtggtgtctt tcttgccttc ggttaacgca
    14341 ttcaacgccg taatcattgt ttcatcggtg accggatcgt taccgataaa catcgagttg
    14401 tctgccttca ccgacagata aaccggtttt tccgggcgcg gctgcggcgt gctggtagaa
    14461 gcaggcaagt tcaccttcac atctaccgtc gctaacggtg ccgccaccat aaagataatc
    14521 agcagaacca acatcacgtc gataaacggc gtcacgttga tatcatgcat ttcgccgtta
    14581 tcgtcgaggt tttcgttaag atgcattgcc atcggatatt atcctgcgcg taatttttgt
    14641 gcgacacgaa ccggatgcgc agcggcgctg gcttccagat ccaggtcacg gctttgcagc
    14701 aacaatacct gcgctgcaac atcacccagc atcgctttaa agccgccaat ctggcgtgca
    14761 aatacgttat agataacgac cgcaggaatc gctgccacga ggccgattgc cgttgctaac
    14821 agagcttctg cgatacccgg cgcaacgact gccaggttag tggtctgcgt ttgcgcgata
    14881 ccaataaagc tgttcatgat gccccagacc gtaccaaaca gaccaacgaa cggagaaatc
    14941 gcgccgatgg ttgccagata gccgttaccg cggcccattt gacgacccac tgcggcgacc
    15001 cgacgctcca gacggaagct ggtacgttct ttaatacctt cgttatcgtc gctgccttct
    15061 gacagttcca gctcattctg cgcttcattg agcaaatgca ggcttaagct tttgctacca
    15121 aaatcagcgg cgatatcgtt ggcctggttt aaggaacgcg cttcagccag cagttgctgc
    15181 tcgcgcttaa ggcgacgctt ctgattgaag aactctacgc tcttactgaa gaagattgcc
    15241 caggtgacta cggaggccaa aataagccca atcatcacgc acttaacgac aatatcggcg
    15301 tgctgataca taccccagac ggaaaggtcc gtctgcatta aattattacc cactgtgtat
    15361 ctccaggacg caagtcacaa aatctgcgca taataatatc aaaacgacgt cgaattgata
    15421 gtcgttctca ttactatttg catactgccg tacctttgct ttcttttcct tgcgtttacg
    15481 cagtaaaaaa gtcaccagca cgccatttgc gaaaattttc tgctttatgc caattcttca
    15541 ggatgcgccc gcgaatattc atgctagttt agacatccag acgtataaaa acaggaatcc
    15601 cgacatggcg gacaaaaagc ttgatactca actggtgaat gcaggacgca gcaaaaaata
    15661 cactctcggc gcggtaaata gcgtgattca gcgcgcttct tcgctggtct ttgacagtgt
    15721 agaagccaaa aaacacgcga cacgtaatcg cgccaatgga gagttgttct atggacggcg
    15781 cggaacgtta acccatttct ccttacaaca agcgatgtgt gaactggaag gtggcgcagg
    15841 ctgcgtgcta tttccctgcg gggcggcagc ggttgctaat tccattcttg cttttatcga
    15901 acagggcgat catgtgttga tgaccaacac cgcctatgaa ccgagtcagg atttctgtag
    15961 caaaatcctc agcaaactgg gcgtaacgac atcatggttt gatccgctga ttggtgccga
    16021 tatcgttaag catctgcagc caaacactaa aatcgtgttt ctggaatcgc caggctccat
    16081 caccatggaa gtccacgacg ttccggcgat tgttgccgcc gtacgcagtg tggtgccgga
    16141 tgccatcatt atgatcgaca acacctgggc agccggtgtg ctgtttaagg cgctggattt
    16201 tggcatcgat gtttctattc aagccgccac caaatatctg gttgggcatt cagatgcgat
    16261 gattggcact gccgtgtgca atgcccgttg ctgggagcag ctacgggaaa atgcctatct
    16321 gatgggccag atggtcgatg ccgataccgc ctatataacc agccgtggcc tgcgcacatt
    16381 aggtgtgcgt ttgcgtcaac atcatgaaag cagtctgaaa gtggctgaat ggctggcaga
    16441 acatccgcaa gttgcgcgag ttaaccaccc tgctctgcct ggcagtaaag gtcacgaatt
    16501 ctggaaacga gactttacag gcagcagcgg gctattttcc tttgtgctta agaaaaaact
    16561 caataatgaa gagctggcga actatctgga taacttcagt ttattcagca tggcctactc
    16621 gtggggcggg tatgaatcgt tgatcctggc aaatcaacca gaacatatcg ccgccattcg
    16681 cccacaaggc gagatcgatt ttagcgggac cttgattcgc ctgcatattg gtctggaaga
    16741 tgtcgacgat ctgattgccg atctggacgc cggttttgcg cgaattgtat aacattgcca
    16801 cttttggaca attttgcaga cattttattg tgaaaagtct taaattgttg cgtccgggat
    16861 caaggcgtcc cggacgattc aggagtacaa taggcagata aaggcttaaa cgctgttcca
    16921 caggaaagtc catggctgtt attcaagata tcatcgctgc gctctggcaa cacgactttg
    16981 ccgcgctggc ggatcctcat attgttagcg ttgtttactt tgtcatgttt gccacgctgt
    17041 ttttagaaaa cggcctgctg cccgcctcat ttttgccagg cgacagcttg ttgatactgg
    17101 caggcgcatt gattgcccag ggggttatgg attttctgcc tacgattgcg attctgaccg
    17161 ccgcagcaag tctgggctgc tggctaagtt atattcaggg gcgctggtta gggaatacca
    17221 aaacggtgaa aggctggctg gcacagcttc ctgctaaata tcaccagcgc gccacctgca
    17281 tgtttgaccg ccacggtctg ctggcgctgc tggctggacg ttttcttgca tttgtccgta
    17341 cgctgctgcc aaccatggcg ggaatttccg gtctgccaaa ccgccgcttc cagtttttca
    17401 actggttaag tggattgctg tgggtcagcg tggtaaccag ttttggctat gccttaagta
    17461 tgattccgtt cgttaaacgc catgaagatc aggtaatgac gttcctgatg atcctgccaa
    17521 ttgccttgtt aaccgctggc ttgttaggca cgctgtttgt ggtgattaaa aaaaaatact
    17581 gtaacgcctg acgattttcc ccgttcccgg ttgctgtacc gggaacgtat ttaattcccc
    17641 tgcatcgccc gcattcttgc cgcatcttcc cccggcgtca caccgaagta acgtttaaac
    17701 tcacggctaa attgcgatgc gctttcatag ccgacgcgca tcgctgctgc gctggccttc
    17761 atgccgtcat ggatgatcat catccgcgcc ttatgcagac ggtaattctt caaatactgc
    17821 aacggcgagg tactggtgac agacttaaaa ttatggtgga acgccgatac gctcatgttg
    17881 gcttctgccg ccagttgctc gacgctcagg ttttcggtgt atttattctc aatccgtttc
    17941 agcacgcggc taatcagact gaagtgagtc tggcgactga ccagcgccag taacgcgccg
    18001 ccgcaaggtc cggtcagcac gtagtacaga atttcgcgga tgatctgttt gccgagaata
    18061 cgcgcatcca gtggtcgctc catcacgtcg agtaaccgct ccgccgcgca taaaatctct
    18121 tctgataacg tggcggagtt aatcccgctg gctgccatcg acggctggaa atgctcatct
    18181 tcgccaatgt ccatcaacag ttcctgtaac tgcaaaatat cgacattgag acgcaaccct
    18241 gccagcggca cctctgacgt ggcataggtt tcgcactcaa acggcaacgg caccgtcagc
    18301 agcaggtatt cattggcatc ataacgaaac acgcgttcat tgatataacc gattttatgc
    18361 ccggaaaaga gaattatgat gccaggctcg tacatcaccg gtgtacgtgc gaaaggcgtc
    18421 tcgccataca acaaacgcac atcgggcaac agttctgaca aactattttc tttatttttc
    18481 agtttattaa ctttatccgc cagcaagcgg caaatctctt cacgtttcat atcgcgtaat
    18541 ttcttaggaa taatgcggca atttgattgt gcgcaatttt gtagcatttc tccagcactc
    18601 tggagaaata ggcaagacat tggcagaaat gagcattgag agccagggcg ctggcgatca
    18661 caatgaaaaa catcaggcag atcgttctct gccctcatat tggcccagca aagggagcaa
    18721 gtaatgaaca actttaatct gcacacccca acccgcattc tgtttggtaa aggcgcaatc
    18781 gctggtttac gcgaacaaat tcctcacgat gctcgcgtat tgattaccta cggcggcggc
    18841 agcgtgaaaa aaaccggcgt tctcgatcaa gttctggatg ccctgaaagg catggacgtg
    18901 ctggaatttg gcggtattga gccaaacccg gcttatgaaa cgctgatgaa cgccgtgaaa
    18961 ctggttcgcg aacagaaagt gactttcctg ctggcggttg gcggcggttc tgtactggac
    19021 ggcaccaaat ttatcgccgc agcggctaac tatccggaaa atatcgatcc gtggcacatt
    19081 ctgcaaacgg gcggtaaaga gattaaaagc gccatcccga tgggctgtgt gctgacgctg
    19141 ccagcaaccg gttcagaatc caacgcaggc gcggtgatct cccgtaaaac cacaggcgac
    19201 aagcaggcgt tccattctgc ccatgttcag ccggtatttg ccgtgctcga tccggtttat
    19261 acctacaccc tgccgccgcg tcaggtggct aacggcgtag tggacgcctt tgtacacacc
    19321 gtggaacagt atgttaccaa accggttgat gccaaaattc aggaccgttt cgcagaaggc
    19381 attttgctga cgctaatcga agatggtccg aaagccctga aagagccaga aaactacgat
    19441 gtgcgcgcca acgtcatgtg ggcggcgact caggcgctga acggtttgat tggcgctggc
    19501 gtaccgcagg actgggcaac gcatatgctg ggccacgaac tgactgcgat gcacggtctg
    19561 gatcacgcgc aaacactggc tatcgtcctg cctgcactgt ggaatgaaaa acgcgatacc
    19621 aagcgcgcta agctgctgca atatgctgaa cgcgtctgga acatcactga aggttccgat
    19681 gatgagcgta ttgacgccgc gattgccgca acccgcaatt tctttgagca attaggcgtg
    19741 ccgacccacc tctccgacta cggtctggac ggcagctcca tcccggcttt gctgaaaaaa
    19801 ctggaagagc acggcatgac ccaactgggc gaaaatcatg acattacgtt ggatgtcagc
    19861 cgccgtatat acgaagccgc ccgctaagct ttttacgcct caaactttcg ttttcgggca
    19921 tttcgtccag acttaagttc acaacacctc accggagcct gctccggtga gttcatataa
    19981 aggaggaacg tatggctaat ccaaccgtta ttaagctaca ggatggcaat gtcatgcccc
    20041 agctgggact gggcgtctgg caagcaagta atgaggaagt aatcaccgcc attcaaaaag
    20101 cgttagaagt gggttatcgc tcgattgata ccgccgcggc ctacaagaac gaagaaggtg
    20161 tcggcaaagc cctgaaaaat gcctcagtca acagagaaga actgttcatc accactaagc
    20221 tgtggaacga cgaccacaag cgcccccgcg aagccctgct cgacagcctg aaaaaactcc
    20281 agcttgatta tatcgacctc tacttaatgc actggcccgt tcccgctatc gaccattatg
    20341 tcgaagcatg gaaaggcatg atcgaattgc aaaaagaggg attaatcaaa agcatcggcg
    20401 tgtgcaactt ccagatccat cacctgcaac gcctgattga tgaaactggc gtgacgcctg
    20461 tgataaacca gatcgaactt catccgctga tgcaacaacg ccagctacac gcctggaacg
    20521 cgacacacaa aatccagacc gaatcctgga gcccattagc gcaaggaggg aaaggcgttt
    20581 tcgatcagaa agtcattcgc gatctggcag ataaatacgg caaaaccccg gcgcagattg
    20641 ttatccgctg gcatctggat agcggcctgg tggtgatccc gaaatcggtc acaccttcac
    20701 gtattgccga aaactttgat gtctgggatt tccgtctcga caaagacgaa ctcggcgaaa
    20761 ttgcaaaact cgatcagggc aagcgtctcg gtcccgatcc tgaccagttc ggcggctaac
    20821 atgcaaattc tcccggtggc ggtaatgttc cgctaccgga cttttcagaa atcatttatt
    20881 cccctcgcgt cccgcccgtt gttactcttc cttgttcagg aatgccaaat ataaggacat
    20941 catcatgcag agccggaagc tcttaaaaga acaactcatc tatatccggg ataaacgcaa
    21001 cggagaggtg aaaaacagat gaaaataata cttctgtttt tagcagccct ggcaagtttt
    21061 accgtacacg cacagcccc
//
LOCUS       DAPHKZ010000074        20924 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.074, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000074 DAPHKZ010000000
VERSION     DAPHKZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20924
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.074"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            116..157
                     /locus_tag="RH288_002908"
     CDS             116..157
                     /locus_tag="RH288_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031947.1"
                     /translation="MVQLVDLARCVSF"
     gene            195..1577
                     /gene="dosC"
                     /locus_tag="RH288_002909"
     CDS             195..1577
                     /gene="dosC"
                     /locus_tag="RH288_002909"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DosC"
                     /protein_id="HDV4031948.1"
                     /translation="MEMYFKRMKDEWTGLVEQADPPIRAKAAEIAVAHAHYLSIEFYR
                     IVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIG
                     IPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDS
                     SASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFG
                     LWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTV
                     SQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDV
                     DKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLR
                     TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGR
                     NRVELWKASL"
     gene            1602..4001
                     /gene="dosP"
                     /locus_tag="RH288_002910"
                     /gene_synonym="pdeO"
     CDS             1602..4001
                     /gene="dosP"
                     /locus_tag="RH288_002910"
                     /gene_synonym="pdeO"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416006.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-sensing cyclic-di-GMP phosphodiesterase"
                     /protein_id="HDV4031949.1"
                     /translation="MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKL
                     WGYKREEVIGNNIDMLIPRDLRPAHPEYIRHNREGGKARVEGMSRELQLEKKDGSKIW
                     TRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
                     CNRAFTEMFGYCISEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRT
                     GEKIWIKASISPVYDVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGE
                     IICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEIQNAQSWSATIRQRDGAPAGIL
                     QIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
                     YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRI
                     EGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDLGKNRDYL
                     LSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIF
                     AETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS
                     QNIHIPALSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFK
                     RIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAI
                     TSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLK
                     I"
     gene            4259..4840
                     /gene="ddpX"
                     /locus_tag="RH288_002911"
     CDS             4259..4840
                     /gene="ddpX"
                     /locus_tag="RH288_002911"
                     /EC_number="3.4.13.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine dipeptidase"
                     /protein_id="HDV4031950.1"
                     /translation="MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHK
                     DAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLWQACPDPQYVVDVTVGSNHSRGT
                     AIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNTIMTGGGFVGIS
                     SEWWHFELPQAASYPLLADQFSCFISPGTQHVS"
     gene            4854..6404
                     /locus_tag="RH288_002912"
     CDS             4854..6404
                     /locus_tag="RH288_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV4031951.1"
                     /translation="MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLD
                     PAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDN
                     AKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
                     YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYP
                     GNKPNFKRVSVKIIGESASRRLQLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLR
                     VTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMRGPIPEGMWGYDATA
                     MQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGIIVKLEKL
                     ANATMRDRVGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKL
                     LRNALATTDQTQRTRDYQQAQKIVIDDAAYVYLFQKNYQLAMNKEVKGFVFNPMLEQV
                     FNINTMSK"
     gene            6406..7428
                     /locus_tag="RH288_002913"
     CDS             6406..7428
                     /locus_tag="RH288_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4031952.1"
                     /translation="MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDR
                     ASDAIVENIRQQLGLDQPLYVQFYRYVSDLFHGDLGTSIRTGRPVLEELRIFFPATLE
                     LAFGALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGH
                     LQILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGI
                     VARQIRSAMLEQLSEDYIRTARASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYG
                     AVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVNLVVDLLYLWIDPRI
                     GRGGGE"
     gene            7425..8321
                     /locus_tag="RH288_002914"
     CDS             7425..8321
                     /locus_tag="RH288_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-dipeptide ABC transporter permease"
                     /protein_id="HDV4031953.1"
                     /translation="MMLSEETSAVRPQKQTRFNGAKLVWMLKGSPLTVTSAVIIVLML
                     LMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLV
                     VVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAM
                     LAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLINWHILRNSLPPLIVQA
                     SLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAV
                     GFNLFGDGIRDLLDPKAGGKQS"
     gene            8318..9304
                     /locus_tag="RH288_002915"
     CDS             8318..9304
                     /locus_tag="RH288_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4031954.1"
                     /translation="MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGES
                     GSGKSVTAMLIMRLLPTGSYCVHRGQISLLGEDVLNAREKQLRQWRGARVAMIFQEPM
                     TALNPTRRIGLQMMDVIRHHQPISRREARAKAIDLLEEMQIPDAVEVMSRYPFELSGG
                     MRQRVMIALAFSCEPQLIIADEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMA
                     VVSQLCDSVYVMYAGSVIESGVTADVIHHPRHPYTIGLLQCAPEHGVPRQLLPAIPGT
                     VPNLTHLPDGCAFRDRCYAAGAQCENVPALTACGDNNQRCACWYPQQEVISV"
     gene            9297..10223
                     /locus_tag="RH288_002916"
     CDS             9297..10223
                     /locus_tag="RH288_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV4031955.1"
                     /translation="MSDTLLTLRDVHINFPARKNWLGKTTEHVHAINGIDLQIRRGET
                     LGIVGESGCGKSTLAQLLMGMLQPSHGQYIRSGSQRIMQMVFQDPLSSLNPRLPVWRI
                     ITEPLWIAKRSSEQQRRALAEELAVQVGIRPEYLDRLPHAFSGGQRQRIAIARALSSQ
                     PDVIVLDEPTSALDISVQAQILNLLVTLQENHGLTYVLISHNVSVIRHMSDRVAVMYL
                     GQIVELGDAQQVLTAPAHPYTRLLLDSLPAIDKPLEEEWALRKTDLPGNRTLPQGCFF
                     YERCPLATHGCEVRQSLAIREDGRELRCWRAL"
     gene            complement(10279..10710)
                     /gene="osmC"
                     /locus_tag="RH288_002917"
     CDS             complement(10279..10710)
                     /gene="osmC"
                     /locus_tag="RH288_002917"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin OsmC"
                     /protein_id="HDV4031956.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEK
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKS
                     EVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS"
     gene            11055..11270
                     /gene="bdm"
                     /locus_tag="RH288_002918"
     CDS             11055..11270
                     /gene="bdm"
                     /locus_tag="RH288_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415998.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HDV4031957.1"
                     /translation="MFTYYQAENSTAEPALVNAIEQGLRAQHGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            11372..11509
                     /gene="sra"
                     /locus_tag="RH288_002919"
     CDS             11372..11509
                     /gene="sra"
                     /locus_tag="RH288_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HDV4031958.1"
                     /translation="MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE
                     K"
     gene            11666..13363
                     /gene="maeA"
                     /locus_tag="RH288_002920"
     CDS             11666..13363
                     /gene="maeA"
                     /locus_tag="RH288_002920"
                     /EC_number="1.1.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HDV4031959.1"
                     /translation="MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLG
                     LLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPV
                     IYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRI
                     TDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAA
                     VTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFM
                     VDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVV
                     WKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGMV
                     LPELKVIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI"
     gene            13497..14507
                     /gene="adhP"
                     /locus_tag="RH288_002921"
     CDS             13497..14507
                     /gene="adhP"
                     /locus_tag="RH288_002921"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415995.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HDV4031960.1"
                     /translation="MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETL
                     CRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDA
                     AKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDG
                     IEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDF
                     RH"
     gene            14653..14937
                     /locus_tag="RH288_002922"
     CDS             14653..14937
                     /locus_tag="RH288_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415994.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HDV4031961.1"
                     /translation="MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTG
                     KAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAEKTVDVSRLRRLVTQ"
     gene            complement(15166..15819)
                     /gene="fdnI"
                     /locus_tag="RH288_002923"
     CDS             complement(15166..15819)
                     /gene="fdnI"
                     /locus_tag="RH288_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit gamma"
                     /protein_id="HDV4031962.1"
                     /translation="MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLT
                     QTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHK
                     VADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPMQVVRYSLLIHAAAGI
                     ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI"
     gene            complement(15812..16696)
                     /gene="fdnH"
                     /locus_tag="RH288_002924"
     CDS             complement(15812..16696)
                     /gene="fdnH"
                     /locus_tag="RH288_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase N subunit beta"
                     /protein_id="HDV4031963.1"
                     /translation="MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKA
                     CQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMH
                     CEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
                     TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEG
                     VGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHY
                     IGIGPNKEVDDDEEDHHE"
     gene            complement(16709..19756)
                     /gene="fdnG"
                     /locus_tag="RH288_002925"
     CDS             complement(16709..19756)
                     /gene="fdnG"
                     /locus_tag="RH288_002925"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(19169..19171),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HDV4031964.1"
                     /translation="MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAK
                     EIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYV
                     NSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLS
                     TGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIR
                     SGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYD
                     KSSWNYQFDENGYAKRDETLTHPRCVWNLLKEHVSRYTPDVVENICGTPKADFLKVCE
                     VLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSL
                     MKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDK
                     NKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDG
                     SIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQSEGGKGVEPLMKMSWNY
                     KQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYT
                     GSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLI
                     QWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETP
                     LGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIA
                     QPEQFVEISETLAAAKGINNGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGI
                     PIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA"
     gene            19988..20869
                     /gene="yddG"
                     /locus_tag="RH288_002926"
     CDS             19988..20869
                     /gene="yddG"
                     /locus_tag="RH288_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415990.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid efflux DMT transporter YddG"
                     /protein_id="HDV4031965.1"
                     /translation="MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLS
                     GLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLW
                     PSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
                     LAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMIFSTPVMIK
                     LISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGA
                     LMVCGGSLLCWLATRRG"
BASE COUNT         5109 a         5315 c         5328 g         5172 t
ORIGIN      
        1 ctgtcaccga aaaataatta cgatgggcta tactcttctg aagaacagta gcgtagattg
       61 aaactgtcct aaatcgctta tttcttttca gtatatcttc atatttcagg agaatatggt
      121 gcagttagtc gatctcgcac gttgcgtttc attttgattc cgtctgattt cccagcctta
      181 taagggtgtg aattatggag atgtatttta aaagaatgaa agatgagtgg accggacttg
      241 tcgaacaggc agatccgccc attcgtgcta aagccgcgga aattgccgtt gcgcatgctc
      301 attatctgag tatcgagttt tatcgaattg tccgcatcga cccgcatgcc gaagaattct
      361 tgagtaatga acaagttgag cggcagttga agagtgcgat ggaacgctgg attattaacg
      421 tgctttctgc ccaggttgac gatgtcgaaa ggctaataca aatccagcat accgtcgcgg
      481 aagtgcatgc ccgcatagga attccggtag aaattgtcga gatggggttt cgggtgctga
      541 aaaaaatcct ctatccggtg atcttctctt cggattattc cgccgcagaa aaacttcagg
      601 tctaccattt ctcgattaac agtattgata tcgcgatgga agtgatgact cgcgcgttta
      661 cctttagtga cagtagtgcc tcaaaggaag atgaaaacta tcgtatcttc tcgttactgg
      721 aaaacgccga agaagaaaaa gaacggcaaa tagcctcaat actttcatgg gaaatagata
      781 ttatctataa aatcctgctg gattctgatt taggcagtag tttgccttta agccaggctg
      841 attttggcct gtggtttaac cataaaggtc gacattattt tagtggtatt gccgaagtag
      901 gccatatctc ccgtctgatt caggatttcg acggtatttt caatcaaacc atgcgtaaca
      961 ccagaaattt gaataacaga agtctgcggg tgaaattttt attacagata agaaataccg
     1021 tatcgcaaat tattaccttg ctgcgtgaat tgtttgaaga agtatcgcgc cacgaagtcg
     1081 gtatggatgt actgacgaaa ttacttaacc gccgtttcct accgactatc ttcaaacgcg
     1141 aaattgccca tgccaaccgg accggtacac cgctgtcagt gctgattatt gacgttgata
     1201 aattcaaaga gatcaacgat acgtggggcc ataacactgg tgatgaaatt ctgcgtaaag
     1261 tctctcaggc cttttatgac aacgtccgca gtagtgatta tgttttccgc tacgggggcg
     1321 atgaatttat cattgttttg actgaagctt ctgaaaacga aacgttacgt accgcagaac
     1381 gtattcgcag tcgggtggag aaaaccaaac tgaaagccgc aaacggcgaa gatattgccc
     1441 tctcactttc catcggtgcc gccatgttta atggtcatcc tgactatgag cgcctcattc
     1501 aaatagccga tgaagctctg tatatcgcca aaagacgagg tagaaaccgt gttgaactct
     1561 ggaaagccag tctttagatg cgccaggatg cagaggtaat catgaagcta accgatgcgg
     1621 ataatgccgc cgatggcatt tttttccccg cccttgagca aaatatgatg ggtgcggtgt
     1681 taattaacga aaatgatgaa gtgatgtttt tcaaccccgc cgcagagaag ctctggggat
     1741 acaaacgtga agaagtcatt ggcaataaca ttgatatgct gattccgcgg gatttgcgtc
     1801 ctgcgcatcc tgaatacatt cgtcacaacc gtgaaggcgg taaagcgcgt gttgagggga
     1861 tgagtcggga gctgcagctg gagaaaaaag acggcagtaa aatctggacc cgttttgcgc
     1921 tatcgaaagt gagcgccgag gggaaagttt attacctggc gctggtacgg gatgccagcg
     1981 tagaaatggc gcaaaaagaa cagacccgac aattgattat tgccgttgac catctcgacc
     2041 gaccggtgat tgtcctcgat ccggaacgcc atattgtgca gtgcaatcgc gcatttaccg
     2101 aaatgtttgg ttactgcatt agcgaagcca gcggtatgca gcccgataca ctcctgaaca
     2161 ttcctgaatt ccctgccgat aaccgcattc gtttacaaca gttgctatgg aaaaccgccc
     2221 gcgatcagga cgaatttctg ctgttgacgc gcaccggtga aaaaatctgg attaaagcct
     2281 ctatcagccc ggtttatgac gtgctcgcgc atctgcagaa cctggtaatg actttctcgg
     2341 atatcaccga agaacggcag attcgccagc ttgaaggcaa tattctcgcc gccatgtgca
     2401 gcagcccgcc atttcatgaa atgggggaaa tcatttgtcg taacatcgaa tctgtactca
     2461 acgaatcgca tgtttcgctg ttcgcactgc gcaacgggat gccgatacac tgggcgtcat
     2521 cttcccacgg tgcagaaatt caaaatgcgc aaagctggtc agcgaccatt cgtcagcgtg
     2581 atggcgcgcc tgcggggatc ctgcaaatta aaacctcgtc aggagcagaa accagcgcct
     2641 ttatcgaacg cgtggcagat atcagccagc atatggccgc gctggcgctg gaacaggaaa
     2701 aaagccgtca gcatattgaa caactcatcc aatttgatcc gatgaccggt ctgccaaatc
     2761 gcaataacct gcacaattac ctcgatgacc tggtcgacaa agccgtctct cccgtggtgt
     2821 atctcatcgg tgttgaccat attcaggatg tgattgatag ccttggctat gcgtgggccg
     2881 atcaggcatt gctggaagtg gtcaatcgct ttcgtgaaaa actcaaaccg gatcagtatc
     2941 tctgtcgtat cgaaggtacg cagtttgtcc tcgtgagcct cgaaaacgac gtcagtaaca
     3001 ttacccaaat cgccgatgag ctacggaatg tggtcagcaa gccgataatg attgacgata
     3061 aacccttccc gcttaccttg agtattggca tcagctacga cctgggtaaa aaccgcgatt
     3121 acttgctctc cactgctcac aatgcaatgg attatattcg caagaatggc ggtaacggct
     3181 ggcagttctt cagcccggcg atgaacgaaa tggtaaaaga gcgtttggtt ttaggcgcag
     3241 cgctgaaaga agcgattagc aataaccaac tgaaactggt ttaccagccg caaatcttcg
     3301 cagaaacggg tgaactgtac ggcatcgaag cccttgctcg ctggcacgat cccctgcatg
     3361 gtcatgtgcc cccttcacgg tttattcctc tcgcagaaga gattggtgaa atcgaaaata
     3421 ttgggcgctg ggtcatcgcg gaagcttgcc gtcagttagc agaatggcgt agccagaata
     3481 ttcatatccc ggcgttatcc gtgaacttgt cggcgctgca ctttcgcagt aatcaactgc
     3541 ctaatcaggt gtctgatgca atgcacgcct ggggtattga cggccaccag ctgacggtag
     3601 aaatcacgga aagcatgatg atggaacacg ataccgaaat ctttaagcgc attcagatcc
     3661 tgcgtgatat gggcgtgggc ttatcggtag atgattttgg tacgggcttt tccggattat
     3721 cccgcttagt cagtcttccg gtaacggaaa tcaaaattga caaaagtttt gtcgatcgtt
     3781 gtctgaccga aaaacgcatc cttgccttac ttgaagccat taccagcatt gggcaaagcc
     3841 tcaatttaac cgtcgtggcg gaaggcgtcg aaaccaaaga gcaatttgag atgctacgca
     3901 agatccactg tcgcgttatt cagggatatt tcttttcccg ccccctaccc gccgaagaaa
     3961 ttccaggctg gatgagcagc gtgttaccgc tgaaaatctg acaaattcct ctcgcccgca
     4021 ctcgcgggtt ttcatttaac gtgacactgt cacttaaata ctgtgatttc agctacgatt
     4081 ccgggagatt ccttccttaa cttcccctct tgcaccaaaa ctgcactacg ctgcacaaat
     4141 gttgatcaaa agttaaaaaa tataacttta agccagcatt ctggcgctta tcccggcatg
     4201 gcatgagatc tgcataagcg gaaagcgcag caatttttgt cttatacagg aaccgtttat
     4261 gtcggatacc accgaactgg ttgatttagc cgtaatcttc cctgatctgg agatcgaatt
     4321 gaaatacgcc tgcgctgata acatcacagg taaagctatt tatcagcaag cgcgttgtct
     4381 gttacacaag gatgcgatta ccgcgctggc gaaaagtatc agcatcgccc agctgtcagg
     4441 gttacaactg gtgatttacg atgcgtatcg cccacaacaa gcacaggcga tgttgtggca
     4501 agcctgccca gacccgcaat atgttgttga tgtgacggtc ggttctaatc acagccgtgg
     4561 cacggcgatc gacctgacgc ttcgtgatga gcacgggaac atcctcgata tgggcgcagg
     4621 gttcgatgaa atgcacgagc gctcccatgc ctatcaccct tccgtcccgc ccgccgctca
     4681 gcgcaatcgg ctgttgctga atacgataat gactggtggc ggttttgtcg gtatctccag
     4741 cgaatggtgg cacttcgaat taccccaggc agcgagttac cctctgctcg ctgatcaatt
     4801 ctcttgtttt atatcccctg gcacacagca cgtcagttaa tcaggaaact gtcatgaaga
     4861 gatcgatatc gtttcgtccc acattgctcg cgctcgtcct tgccacaaat ttcccggttg
     4921 cgcacgccgc cgtaccaaaa gatatgctgg tgattggtaa ggccgccgat ccacaaaccc
     4981 tcgacccggc ggtaacaata gataataacg actggacagt gacctacccg tcttatcagc
     5041 ggctggttca gtacaaaacg gacggtgata aaggctcaac cgacgttgaa ggcgatctgg
     5101 caagtagctg gaaagcgtct gacgatcaaa aagagtggac gttcaccctg aaagataatg
     5161 ctaaatttgc cgatggcaca cctgtcactg ccgaagcagt aaaactttct tttgagcggc
     5221 tactaaaaat cggccagggg ccagcagaag catttcccaa agatttaaag attgatgctc
     5281 ccgacgaaca tacggtgaag tttaccctta gccaaccatt cgcaccgttc ctctacacgc
     5341 tggcgaatga cggtgcatcc attatcaatc cggcggtctt aaaggaacat gcagcggatg
     5401 atgctcgcgg cttcctcgcg caaaataccg ccggttccgg accatttatg ctgaaaagct
     5461 ggcaaaaagg tcagcaatta gttctggtgc caaatccgca ttacccaggc aataaaccga
     5521 acttcaaacg ggtatcggta aaaattattg gtgaaagtgc ctcccgtcgc ctgcagctct
     5581 cccgtggcga cattgacatt gccgatgcgc tgccggtgga tcaactcaac gccctgaagc
     5641 aggaaaataa agtcaatgtg gcagagtatc cgtcactgcg cgttacctat ctgtatctga
     5701 ataacagcaa agcgcctctt aatcaggcgg atctgcgtcg ggccatttcc tggtctaccg
     5761 attatcaggg catggttaac ggcattctga gtggtaacgg aaaacagatg cgcggcccga
     5821 ttccggaagg catgtggggc tacgatgcga cggcaatgca atacaaccat gacgaaacga
     5881 aagccaaagc cgaatgggat aaagtgacga gcaaacccac cagcctgacg tttctctact
     5941 ccgataacga tccgaactgg gagcctattg ctctggcgac acaatccagt ctcaacaagc
     6001 tgggcatcat tgtgaagctg gaaaagctgg cgaacgccac catgcgcgac agagtgggta
     6061 aaggtgatta cgacattgcg attggcaact ggagtccgga ttttgccgac ccgtatatgt
     6121 ttatgaatta ctggtttgag tcagacaaaa aaggtctgcc gggtaaccgc tcgttctatg
     6181 aaaacagtga ggtcgataag ttactgcgca atgcgcttgc gaccaccgac cagacgcagc
     6241 gtacccggga ctaccagcag gcacagaaaa tcgtcattga tgacgctgct tatgtgtacc
     6301 tgttccagaa aaactaccaa ctggcgatga acaaagaggt gaaaggcttt gtgttcaatc
     6361 ccatgctgga acaggtcttc aatatcaata ccatgagtaa ataacgtgac cttctggagt
     6421 attttacgcc aacgctgctg ggggctggtg ctcgtggtgg cgggcgtctg cgtgattacg
     6481 tttattatct cgcatctgat ccctggtgat ccggcgcggt tactggcggg tgaccgcgcc
     6541 agcgatgcta tcgtggaaaa tattcgccag caactgggac tggaccagcc actgtatgta
     6601 cagttttacc gctacgtcag cgacctgttt catggtgacc tgggaacatc cattcgtacc
     6661 gggcgtccgg tgctggaaga gttgcgtata tttttcccgg cgacgctgga gctggctttt
     6721 ggtgccctgc tgctggcact cctgattggc atcccgctgg gcatactctc tgcagtctgg
     6781 cgaaatcgct ggctggatca tctggtgcga ataatggcca ttaccggaat ctccacacct
     6841 gcgttctggc ttgggctggg cgtcattgtg ctgttttatg gtcatctgca aattcttccc
     6901 ggcggcggaa ggcttgatga ctggctggat ccaccaacgc acgttaccgg cttttatctg
     6961 ctcgatgcgc tgcttgaagg caacggtgaa gtcttcttca atgcgttgca acatctcatc
     7021 ttaccggcat taacgctggc gttcgttcac ctgggaattg tcgctcgcca gatccgctca
     7081 gcgatgctgg aacaattgag tgaagactac attcgtaccg cccgggccag cggcttgccc
     7141 ggctggtata tcgttttatg ttatgcgcta cccaatgcgt tgatcccatc gattaccgta
     7201 ttgggtttgg cgctgggcga tttgttgtat ggcgcagtgc tcaccgaaac cgtttttgcc
     7261 tggcccggaa tgggtgcatg ggtagtaaca tcaatacagg cgctcgactt cccggcagtg
     7321 atgggctttg ccgtcgtggt ttcatttgct tatgtgctgg tcaacctggt ggtggatttg
     7381 ctctatttgt ggattgatcc gcgtatcgga cgtggaggtg gtgaatgatg ctaagcgagg
     7441 aaacgtccgc cgtacgccca caaaaacaaa cgcgatttaa cggtgcaaaa ctggtatgga
     7501 tgctgaaagg cagtccgctc accgtgacca gcgcagtcat cattgtatta atgctattga
     7561 tgatgatttt ttcaccgtgg ctggcgacgc atgatcccaa cgccattgat ttaaccgccc
     7621 gccttttgcc gccttctgcg gcgcactggt ttggcaccga tgaagtggga cgcgatctgt
     7681 ttagccgcgt actggtcggc agtcagcaat caattctcgc cggattagtc gtggttgcca
     7741 ttgcgggtat gattggttcg ctactcggat gtctatccgg tgtgcttggt ggacgcgcag
     7801 acgccatcat catgcgcatc atggacatta tgctgtcgat tccttcgttg gtactgacaa
     7861 tggcactggc tgccgctctc gggccgagtt tgtttaacgc catgctggct attgctattg
     7921 tgcgaattcc cttttatgtg cgcctggctc gggggcaagc attagttgta cgccagtata
     7981 cctatgttca ggcggcgaaa acctttggcg cgtctcgttg gcatctgatc aactggcata
     8041 ttttacgtaa ctccctaccg ccgctgatcg tgcaggcatc gctggatatc ggtagcgcga
     8101 ttttaatggc cgccacgttg ggatttattg gcctgggtgc tcaacaaccg agtgctgaat
     8161 ggggcgcgat ggtagcaaat ggtcgcaact atgtactcga tcagtggtgg tattgcgcat
     8221 ttccgggggc agcgattttg cttaccgccg tcgggtttaa tctctttggt gatggtattc
     8281 gcgatctgct tgacccgaaa gcaggaggaa agcagtcatg acccaacccg ttctggacat
     8341 tcaacaactg catttgagtt tccccggttt taacggtgat gttcacgcgc tcaacaatgt
     8401 gtccttgcag attaaccgcg gtgaaattgt cggtctggtg ggagaatccg gctcaggtaa
     8461 atcagtcacc gcaatgctga ttatgcgtct gctaccgacg ggcagttatt gcgtacatcg
     8521 ggggcagatt tccctgctgg gagaagatgt tcttaacgcg cgggaaaaac agcttcgtca
     8581 gtggcgcggc gcacgagtgg cgatgatctt tcaggaaccg atgaccgccc tcaatccgac
     8641 acgtcgaata ggtcttcaga tgatggacgt gatccgccat catcaaccaa taagtcgtcg
     8701 ggaagccaga gctaaagcga ttgacctgct ggaagagatg caaatcccgg atgccgtgga
     8761 agttatgtcg cgctatccgt ttgagctttc aggtggtatg cgccagcggg taatgattgc
     8821 gctggcattc tcctgcgagc cgcaattgat tattgccgac gaaccgacta cggcgctgga
     8881 cgtcacggtg cagttgcagg tactgcgttt gcttaaacat aaagcccgcg ccagtggaac
     8941 tgcggttctg ttcatcagcc atgatatggc cgtggtgtcg caactgtgcg atagcgttta
     9001 cgtgatgtat gccggaagcg taattgaaag cggcgtgacg gcagacgtta tccatcatcc
     9061 ccggcatccg tataccattg gtttgctgca atgcgcacca gaacatggag taccacgcca
     9121 gctattaccc gccattccag ggacggtacc aaacctcacc catttgcctg acggctgcgc
     9181 ttttcgcgat cgttgctatg cggcaggtgc acagtgtgaa aacgtcccgg cgctgacagc
     9241 gtgtggtgac aacaaccagc gctgtgcctg ttggtatccg cagcaggagg ttataagtgt
     9301 ctgacacgtt attaacgtta cgcgacgtcc atatcaattt cccggcccgt aaaaactggc
     9361 ttggtaaaac tacggaacat gttcatgcca ttaatggtat tgatttacag atccgccgtg
     9421 gtgaaacctt agggatcgtc ggcgagtcag gctgcggcaa aagcaccctc gcacagcttt
     9481 taatgggtat gctgcaaccg agccacgggc agtacatccg ttctggctca caacgcatta
     9541 tgcagatggt gtttcaggac ccgctctctt cgcttaatcc gcgcttaccg gtgtggcgca
     9601 tcatcacaga accgctctgg atagctaagc gtagtagtga acaacagcgg cgagcgttgg
     9661 cagaggagtt ggctgtgcag gtgggtattc gtccggagta tctcgaccgc ctgcctcatg
     9721 cgttctccgg cgggcagcgg caacgtatcg ccattgccag agcactctct tcgcagcctg
     9781 acgtgattgt gcttgatgag ccaacctctg cgctggatat ctccgttcag gcgcagatcc
     9841 tcaatttact ggtaacgcta caggaaaatc acgggctgac ctatgtgctg atttcacaca
     9901 atgtctcggt gatacgtcat atgagcgatc gggtggcggt gatgtatctc gggcagattg
     9961 tagaactggg cgacgcgcag caggtgctga cggcacctgc acatccatac acccgattat
    10021 tgctggattc cctccccgcc attgataaac cgctggagga agaatgggca ttacgtaaaa
    10081 cggatctgcc gggaaaccgc acgttgccgc aaggctgttt tttctacgaa cgttgcccgc
    10141 tggcaaccca cggatgtgaa gtccggcaat cattagcaat aagggaggac ggacgtgagc
    10201 tccggtgctg gcgggcgctg tagagatgct aacaacgcat caggcattca cgcgcctgac
    10261 gcgtcatccg gcaatgcttt acgatttcaa ctggtaatcc agcgtaattt ccgctttcag
    10321 tacctgagag accgggcatc ctgcttttgc tttctggatt atgccgtcaa aggtagaggc
    10381 atcaataccc ggcaccgcaa cttcactctt cagtgcgatt ttcgtaatcg caaaaccggc
    10441 atccacttta tccagcgaca catcggcggt ggtatcaatc gatgttggcg tgaatcccgc
    10501 ttcccccagc attaatgaaa gcgccattga gaaacatgcg gcatgcgctg cgccaatcag
    10561 ttcttcaggg ttggttcctt tttcgccttc aaaacgcgtg ttaaatccat acggctgttg
    10621 gttcagcacg ccactctcgg tggatactgt tcccttcccg cgtttgatat cgccttccca
    10681 gtgtgcctga cctttcttat ggattgtcat tgttgctctc ctgtgggctt aaaaaggaaa
    10741 ttatagacta cgtgagaaac agcacgagga taagcaggat attccgaata aaatccggcg
    10801 aaaatattac ttctgcactt aaattaaatt cccacaatag attaccggga atatataacc
    10861 caaaagatat tgtatcaata ttaatcggat cataccaatc acaatcccta tgaatatcat
    10921 ggtgttaaaa tataaaaatc atcaaccagg actaatctta acaacgaagc ggcaaatatt
    10981 tgccatgctg aatgtgcttt ataaatctgc gatccgtagc agacaccata aatacacaga
    11041 cacggagaat cactatgttt acttattatc aggcagaaaa ttcaacagca gaacccgctc
    11101 tggttaatgc cattgagcaa ggccttcggg cacagcatgg tgttgtcact gaagatgaca
    11161 ttctcatgga gctgaccaaa tgggttgaag cttctgataa cgacatcctc agtgatatct
    11221 accagcaaac gatcaattat gtggtcagtg gccagcaccc tacgctttaa ggtgctatgc
    11281 ttgatcggca acctaattta ggggtttagc acgtgtttct tcgctacggc gatgttgtcc
    11341 ttaaaactag ctacaggatt gaggagttaa aatgaaatcg aaccgtcagg cacgtcatat
    11401 tcttggactg gaccataaaa tttctaacca gcgcaaaata gttaccgaag gtgacaaatc
    11461 cagcgtagta aataacccaa ccggcagaaa acgccccgct gaaaagtaat tcataaccat
    11521 cagtcctcaa tgacgattaa acaccattgc ctgcgcaatg gtgtttttgt ttttatctgc
    11581 tttatacttg aggccgacgc cctggcggta aagcaaagac gataaaagcc ccccagggat
    11641 ggatattcaa aaaagagtga gtgacatgga accaaaaaca aaaaaacagc gttcgcttta
    11701 tatcccttac gctggccctg tactgctgga atttccgttg ttgaataaag gcagtgcctt
    11761 cagcatggaa gaacgccgta acttcaacct gctggggtta ctgccggaag tggtcgaaac
    11821 catcgaagaa caagcggaac gagcatggat ccagtatcag ggattcaaaa ccgaaatcga
    11881 caaacacatc tacctgcgta acatccagga cactaacgaa accctcttct accgtctggt
    11941 aaacaatcat cttgatgaga tgatgcctgt tatttatacc ccaaccgtcg gcgcagcctg
    12001 tgagcgtttt tctgagatct accgccgttc acgcggcgtg tttatctctt accagaaccg
    12061 gcacaatatg gacgatattc tgcaaaacgt gccgaaccat aatattaaag tgattgtggt
    12121 gactgacggt gaacgtattc tggggcttgg tgaccagggc atcggcggga tgggcattcc
    12181 gatcggtaaa ctgtcgctct ataccgcctg tggcggcatc agcccggcgt atacccttcc
    12241 ggtggtgctg gatgtcggaa cgaacaacca acagctgctt aacgatccgc tgtatatggg
    12301 ctggcgtaat ccgcgtatca ctgacgacga atactatgaa ttcgttgatg aatttatcca
    12361 ggctgtgaaa caacgctggc cagacgtgct gttgcagttt gaagactttg ctcaaaaaaa
    12421 tgcgatgccg ttacttaacc gctatcgcaa tgaaatttgt tcttttaacg atgacattca
    12481 gggcactgcg gcggtaacag tcggcacact gatcgcagca agccgagcgg caggtggtca
    12541 gttaagcgag aaaaaaatcg tcttccttgg tgcaggttca gcgggatgcg gcattgccga
    12601 aatgatcatc gcccagaccc agcgcgaagg attaagcgag gaagcggcgc ggcagaaagt
    12661 ctttatggtc gatcgctttg gcttgctgac cgacaagatg ccgaacctgc tgcctttcca
    12721 gaccaaactg gtgcagaaac gcgaaaacct cagtgactgg gataccgaca gcgatgtgct
    12781 gtcactgctg gatgtggtgc gcaatgtaaa accagatatt ctgattggcg tctcaggaca
    12841 gaccgggctg tttacggaag agatcatccg tgagatgcat aaacactgtc cgcgtccgat
    12901 cgtgatgccg ctgtctaacc cgacgtcacg cgtggaagcc acaccgcagg acattatcgc
    12961 ctggaccgaa ggtaacgcgc tggtcgccac tggcagcccg tttaatccag tggtatggaa
    13021 agataaaatc taccctatcg cccagtgtaa caacgccttt attttcccgg gcatcggtct
    13081 gggtgttatt gcttccggcg cgtcacgtat caccgatgag atgctgatgt cagcaagtga
    13141 aacgctggcg cagtattcac cattggtgct gaacggcgaa ggtatggtac tgccggaact
    13201 gaaagttatt cagaaagtct cccgcgcaat tgcgtttgcg gttggcaaaa tggcgcagca
    13261 gcaaggcgtg gcggtgaaaa cctctgccga agccctgcaa caggccattg acgataattt
    13321 ctggcaagcc gaataccgcg actaccgccg tacctccatc taagcctgcg cccggtagtg
    13381 aaggctaccg ggctatttcc ctctcccttt ttcagatctc atccatactg ggtagtggcg
    13441 aataaatctc atttgcctca cctgctatgc agaacatcat ccgaaaagga ggaactatga
    13501 aggctgcagt tgttacgaag gatcatcatg ttgacgttac gtataaaaca ctgcgctcac
    13561 tgaaacatgg cgaagccctg ctgaaaatgg agtgttgtgg tgtatgtcat accgatcttc
    13621 atgttaagaa tggcgatttt ggtgacaaaa ccggcgtaat tctgggccat gaaggcatcg
    13681 gtgtggtggc agaagttggc ccaggtgtca cctcattaaa accaggcgat cgtgccagcg
    13741 tggcgtggtt ttacgaagga tgcggtcatt gcgaatactg taacagtggt aacgaaacgc
    13801 tctgccgttc agttaaaaat gccggataca gcgttgatgg cgggatggcg gaagagtgca
    13861 tcgtggtcgc cgattacgcg gtaaaagtgc cagatggtct ggactcggcg gcggccagca
    13921 gcattacctg tgcgggggtc accacctaca aagccgttaa gctgtcaaaa attcgtccag
    13981 ggcagtggat tgctatctac ggtcttggcg gtctgggtaa cctcgccctg caatacgcga
    14041 agaatgtctt taacgccaaa gtgatcgcca ttgatgtcaa tgatgagcag ttaaaactgg
    14101 caaccgaaat gggcgcagat ttagcgatta actcacacac cgaagacgcc gccaaaattg
    14161 tgcaggagaa aactggtggc gctcacgctg cggtggtaac agcggtagct aaagctgcgt
    14221 ttaactcggc agttgatgct gtccgtgcag gcggtcgtgt tgtggctgtc ggtctaccgc
    14281 cggagtctat gagcctggat atcccacgtc ttgtgctgga tggtattgaa gtggtcggtt
    14341 cgctggtcgg cacgcgccag gatttaactg aagccttcca gtttgccgcc gaaggtaaag
    14401 tggtgccgaa agtcgccctg cgtccgttag cggacatcaa caccatcttt actgagatgg
    14461 aagaaggcaa aatccgtggc cgcatggtga ttgatttccg tcactaagag gcctttgctg
    14521 cgactgccat gttcgggtcg cagcatcgca cactctccaa catgaaatgg ctaaatggat
    14581 tattgttgcg taggaaggaa caataatgat agtgttccca gtgaaggaac gctactgaga
    14641 gtaaagacac taatgaaaat ggccaatcat ccccgcccgg gggacattat tcaggaatca
    14701 ctggacgaac ttaatgtcag cctgcgcgag tttgccagag caatggaaat tgctccctca
    14761 acggcaagcc gattgctgac aggaaaagca gctttgacgc cagaaatggc gattaaactt
    14821 tccgtggtga tcggcagttc gccgcaaatg tggctgaatc tgcaaaacgc ctggagtctg
    14881 gcagaggcag aaaaaacagt ggatgtgtcg cgattacgcc gtctggttac gcaataaaaa
    14941 aatggcactt tataaagcgc catttagaac tgatgacaaa cgcaacattg cctgatgcgc
    15001 tacgcttatc aggcctacac gttcactgca atctattgga tttgaagggt tttcatgccg
    15061 gataaggcgt tcacgccgca tccggcatga acaaagccta cgttgtctac aatatgaaaa
    15121 tggcgccttt tacagcgcca ttttcagctt aaagttcaaa agagattata tcccttcttc
    15181 actctctttt ttcgcttctg ccttctcgat ttcacgatac cagcgcggat ggtgtttctt
    15241 cgcccagcga cgacttacct tcccttcgat catcccttta atcgatcctt tcacccaaaa
    15301 tgccatatac atatggatca ggatggcgtg gatcaggatg atgccggcag ccgcgtggat
    15361 cagcaggctg tagcgaacaa cctgcatcgg gaagtactgc gcaaagtacg gacgccagat
    15421 aatcaccccg gtcaccagca gcacgaaaat catgctcatg atcgaccaga acatcatctt
    15481 ttgcccggcg ttgtacttac caacatccgc cactttgtgc tcattgcctt ttaatacttc
    15541 gacaatgttc aacagccacg gaatatcttt cttatccggg atgttgtgat gcacaaaacg
    15601 cacaaacata aacatcagtg cgacgaaaat cgcaatgccg aagaacgggt gcaaaatgcg
    15661 tcccatctgc ggcgtaccga aggtttgcgt cagccattgc agcgtcggga agaagaacga
    15721 aatcccggac agcgccacca ggaagaagca aatcaccacg gtccagtgac aggcgcgatc
    15781 aataaatttg gtgcgcacaa tcattttcga cttactcatg atgatcctcc tcgtcatcgt
    15841 ccacttcctt attcgggcca ataccgatgt agtggaaaat caacccggca aaagtggcaa
    15901 taaagccagc cgctgccagc ggtttcaacg cgcctttcca caggcttacc gaggtgtcga
    15961 tcttcggatc tttcggcaga ccgtgataca gctccggctg atcggcgtga tgcagcacgt
    16021 acataacgtg cgtaccaccg accccttccg ggttgtagac gccagcatgt tcgtaaccac
    16081 gcgctttcag tttcgccacg cgctgttccg ccagctccag catctccttc ttggtgccga
    16141 agtggatagc cccggtcgga caggttttca cacaagccgg ttcctggccg acgctgacgc
    16201 gatcgacgca gagcgtgcat ttatataccc ggttatcctc tttgttgagg cgcggaatat
    16261 taaacggaca cccggcaatg cagtaaccac agccgatgca gttttccgac tggaaatcga
    16321 caatcccgtt agcgtactga atgattgcac cagcagacgg gcacgcctta aggcagcccg
    16381 gatcttcaca gtgcatacag ccgtctttac ggatcagcca ctccagcttg ccgttctgtt
    16441 cggtttcgct aaagcgcatc accgtccagg acttggcgct cagatcggcg gggttatcgt
    16501 aaaccccgac gcagtgcccc acttcatcac ggatgtcgtt ccactccgaa cacgccacct
    16561 gacaggcttt acaaccgata caggtggaaa cgtcgataag ttttgcgact tctgctttgt
    16621 aatcacgcac ctgagaaggc ggcgtgatgg agttagttgc ggaccttttg ataatgtcct
    16681 gcgtttccat agccatctgt tcgccccctt acgccttctc gatgttgact aagaacgctt
    16741 tatattccgg cgtttgcgag tttgcatcac cgacattcgg cgtcagagtg ttagcgatat
    16801 aacctttacg cgcgacaccc tcaaagcccc agtggattgg aatacccacc gtttcaacct
    16861 gctgaccgtt tacattcagc ggcttcagac ggcgcgttac cactgccacc gcgcggataa
    16921 agccacgttt gcttgagaca gtgacacgat cgccattatt aatgcctttc gccgccgcca
    16981 gcgtttcgct gatttccaca aactgttccg gctgagcaat tgcgttgagc aatgcgtgct
    17041 tggtccaggt gtggaagtgc tcggtcagac gataggtcgt acccacatac gggaactgct
    17101 cttttttacc catccgcagc gcgtcttgtt catacagacg aacaaccggg ttagacacca
    17161 cgttcggatg cagcgggtta gtgcccagcg gcgtttcaat cggctcgtag tgttccggga
    17221 acggaccttc cgccattttg ttgatggcaa acaggcgtcc catcccttcc ggctgcatga
    17281 taaacggccc ggttggcgta cccggtgcgg cattgccgaa gtcaggaata tcgttacccg
    17341 tccacttgct gccgttccac tggatcagca tccgtttcgg atcccacggt ttaccgttga
    17401 tatccgccga agcacggttg tacagcacgc gacggttgag cggccacgcc caggcccatc
    17461 ccagcgtatt ccccagaccg gacgggtcgg agttatcgcg gttagccatc tggttgccct
    17521 gctctgtcca gctaccggtg tagatccagc aagaagatgc ggttgtaccg tcatcacgca
    17581 gatgcgcaaa gctactcagc aactgacctt tcttcgcaat aagcacgcca ttagcgtcat
    17641 agagatcttc cagcgcgtag ccgttgttct ctttagccac ttcgtcagat tgcggttcgt
    17701 gcggctgctt gtagttccag ctcatcttca tcagcggttc tacgccttta ccaccttcgg
    17761 actggtacag ctcgcgcaga tgatggtaga tacccgccag aatttcaccg tcgttacgcg
    17821 cttcgcccgg cgcgtcctga cctttccagt gccactgcaa ccagcgaccg gagttagcga
    17881 tagaaccatc ttcttcagca aagcaggtcg aaggcagacg gaatacttca gtctgaatag
    17941 acgccggatc gacatcgttc gactcaccgt ggttctgcca gaaggtagag gtttcagtca
    18001 ccagcggatc gataaccacc atgtacttca gcttgctcag gcagctcacc actttgtttt
    18061 tgtccgggaa ggacgcaacc gggttaaagc cctggcagaa ataaccggtg actttgcctt
    18121 catccatcat gttgaaatac ttgatgacgt cgtaggtctg gtcccacttc ggcagccagt
    18181 catagcccca gttgttctct ttctgcgcgg catcgccata gaaagatttc atcaggctaa
    18241 cgaagaactt cggatagttg ctccagtagt tcacctgatc agccagcgtc gctttcggcg
    18301 tgttcgcttc cagatacgac tgcaaatcaa cctgtttttc tgacggcagc gtcagataac
    18361 ctggcaggct ggtagagagc aggcctaagt cagtcaagcc ctgaatgttg gagtgaccac
    18421 gcaatgcgtt cacgccgcca ccggccatac ccatgttacc gagcagcaac tggatcatcg
    18481 ccatagtacg gatgttctgc gcacccacag tgtgctgcgt ccagcccagc gcgtacagga
    18541 aggtggttgt gcgatccggt gcgctggtgg aggccagcac ttcacacact ttcaggaagt
    18601 cggcttttgg cgtaccgcag atgttttcaa cgacgtccgg cgtgtagcgg gaaacgtgct
    18661 ctttcagcag gttccacaca cagcgcggat gagtcagtgt ttcatcgcgt ttcgcatagc
    18721 cgttttcatc gaactgatag ttccaggacg atttatcgta ttgacgtttt tcagcgtcgt
    18781 agccgctgaa cagaccgtct tcgaaagcaa aatcatcacg caccagcagg ctggcgttgg
    18841 tgtaatgctt aacgtattcg gcgttgattt tgttgttttc gatcaggtag cgcaaaacgc
    18901 cagacaggaa cgtaatgtcc gtaccggaac gaataggcgc gtaaatatcc gccacagaag
    18961 cggtacgcgt aaaacgggga tcgacaacga tcaaggttgc gtcgttgttg tttttcgctt
    19021 ccatcgccca gcggaaaccg acgggatgcg cttcagcagc gttaccgccc atcaccatca
    19081 cgacgttagc gtttttgata tccacccagt ggttggtcat cgcaccgcga ccaaatgttg
    19141 gagcaagact tgctaccgtt ggtccgtgtc agacgcgcgc ctggttgtct accgccagca
    19201 tcccgaggga gcgggcaaat ttctgggtca gcatcccggt ttcgttgctg gcaccggagg
    19261 cacacagcat accggtagaa agccaacggt ttaccgttac gccctgctcg ttcttttcaa
    19321 taaagttagc gtcacggtca gctttcatca gcttcgcaat acgggagaat gcttcttccc
    19381 agctaatgcg ctgccatttg tcagaacctg gcgcacgata ttccgggtag cgcagacggt
    19441 tttcactgtt gacgtaatcc agcaaaccgg cccctttcgg gcacagcgca ccacggctta
    19501 ccggatgatc cgggtcacct tcaatgtgat aaatcgcttc tctggcgttt tttgcgccat
    19561 cacccaggct atacatcaat agcccgcaac ctacggaaca gtatgtgcag gtgttacgga
    19621 tctctttagc gcgtaataat ttgtagtttc gcgcctgagc cagtgcttgc ttcggggcaa
    19681 agcccaatgc cgctactgtt gttccagcca taccgcccgc gcagatttta aaaaattgtc
    19741 tgcgactgac gtccattgct ttcctctttt ttcaggggta ttactgcgcg aggaaactaa
    19801 cagtaaaatt ctgaatcttt ttgcgcgaaa tcaaaaagaa cacgtgtttg ccacaaaata
    19861 atccgcctgc gcaaattgac ctacctcaat agcggtagaa aaacgcacca ctgcctgaca
    19921 ggccagttaa aaaaatgcta taaaattcag cttaattttt aacggcaaga gagacaaaac
    19981 agcgagcatg acacgacaaa aagcaacgct catagggctg atagcgatcg tcctgtggag
    20041 cacgatggta ggattgattc gcggtgtcag tgaggggctc ggcccggtcg gcggcgcagc
    20101 tgctatctat tcattaagcg ggctgctgtt aatcttcacg gttggatttc cgcgtattcg
    20161 gcaaatcccg aaaggctatt tactcgccgg gagtctgtta ttcgtcagct atgaaatctg
    20221 tctggcgctt tccttagggt atgcggcgac ccgtcatcag gcgattgaag tgggtatggt
    20281 gaactatctg tggcccagcc tgacaattct ctttgccatt ctgtttaatg gtcagaaaac
    20341 caactggttg attgtacctg gattattatt agccctcgtc ggcgtctgtt gggtgttagg
    20401 cggtgacaat gggttacatt atgatgaaat catcaataat atcaccacca gcccattgag
    20461 ttatttcctg gcgttcattg gtgcgtttat ctgggcagcc tattgcacag taacgaataa
    20521 atacgcacgc ggatttaatg gaattaccgt ttttgtcctg ctaacgggag caagtctgtg
    20581 ggtttactat tttcttacgc cacaaccaga aatgatattt agcacgcccg tcatgattaa
    20641 actcatctct gcggcattta ccttaggatt tgcttatgct gcatggaatg tcggtatatt
    20701 gcatggcaat gtcaccatta tggcggtagg ttcgtatttt acgcctgtac tttcctcagc
    20761 gcttgcagcc gtgctgctca gcgccccgct gtcgttctcg ttctggcaag gcgcgctgat
    20821 ggtctgcggc ggttccctgc tctgctggct ggcgacacgt cgtggttaaa ataactgccg
    20881 ggtctacggc ccggtagtta atcagataaa ttccgacaat atta
//
LOCUS       DAPHKZ010000075        20797 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.075, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000075 DAPHKZ010000000
VERSION     DAPHKZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20797
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.075"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            128..433
                     /locus_tag="RH288_002927"
     CDS             128..433
                     /locus_tag="RH288_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031966.1"
                     /translation="MLMLNISVAKYIVKEFTSKQLNDLNELSQKLTEELKELPVREVK
                     KGIRRSQEEVKSFILKLMEQNPSVSATHALREFRDSGNSFEEKRFRAEFKALREAKP"
     gene            507..1757
                     /locus_tag="RH288_002928"
     CDS             507..1757
                     /locus_tag="RH288_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-guanine transglycosylase"
                     /protein_id="HDV4031967.1"
                     /translation="MSKLKYFFPDSQDFIDPSFDFFRETRNEHRVRQRDDHYPHEVFS
                     HPYDGMLVSKAVVDGLGGGESKYTRAQRLRYFRNGMKHFFRLPENMETMGDCGAFTYV
                     NQDVPPYRVEEVIEFYETSRFNYGVSLDHIVFGYERPGEVFSGEVLTECRRRQDITLT
                     LAQEFLNKSQKSCFTPFGVAHGWNKNSYRQSVEALLAMGYKNITMGGMVPLKTTQILE
                     TLEEIKPLLKSDTRVHLLGIARPESFADFIKFGVTSIDSTTPLQQAFKDRKNNYHTPD
                     GPAYTAVRVPQFDANPSLSRKIKSGVIDQDIARHLEKDAMNALFEYDKGALPLEKTLE
                     AVLAYERLHSGEKEANKIRADYERTLGERPWKQCQCNICQAIGINVIIFRGAERNRRR
                     GFHNIQVLYNRLQHTLSLRSEELS"
     gene            1754..2881
                     /locus_tag="RH288_002929"
     CDS             1754..2881
                     /locus_tag="RH288_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016538301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DGQHR domain-containing protein"
                     /protein_id="HDV4031968.1"
                     /translation="MSEYRVPALRIRQGEERQLYSLAIEGKQISKIAAISRIRRGEEN
                     LVGYQRPEVRNHIREIQRYIESKNPMIPNPVIIAFDKRVRFEPLTDNGDMGHLVIPFS
                     EDKDFEKPGFIVDGQQRTAALRDAEIDSFMMPVSAFIANDAEEQREQFMLVNSTKPLP
                     KTLLYELAPHTHGRLPSDLQMRKFPSLLTQRLNFGEGPLAGRIKTATNPDGVIADNSM
                     IKMIDASLREGALYRFRDPSTGLGDEVKMVKLLNNFWSAVETVFTDDWDKKPRYSRLL
                     HGVGILALGSLMDEIDQVHQDYKGEPGWTEIPSYTRFVEELNRIKPLCAWSSGAWNFG
                     TDIDGQPIVRKWNELQNLSKDISLVTDYLVTSYIKAANANI"
     gene            complement(2905..5088)
                     /locus_tag="RH288_002930"
     CDS             complement(2905..5088)
                     /locus_tag="RH288_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031969.1"
                     /translation="MTNVPQWLRDFFGNGNLLKLDRLLDNVENAYPADLKAVLLPLYE
                     SATDAQWPLILPWCDAHRWVFFAAADTARTTQELSNVLNARLGSADVIADRKVTFVPA
                     QGATSLSETALLTHCPAGFIRIELLPTKLKDKPAKERVFAALKDVIVLFRDRPSIVRT
                     VKRPFGRILSDFILANSQKDEATSDALLQELKNNGTLSRRNLMLLELQQAGKLEKWDT
                     LLNHDSLADLVRGRIPTTLMRMLLKAYQQRYFTPDSHGYPQASPADLRPQCLALNPLF
                     TQIPFLSQDETDFAAWKTWATGVMLIGEVDLLNALPERLKTDWLNGLHTWASRPFNLV
                     SPSATTATTSVPDTLQQLAAYLQTSLTATQEEIIGYAQTLHTLDQQLIEEAMAVPLLK
                     TLIEEIRHLTNPQIVGWDICFSRLCQSEVDSNSLVQLVALESENWPADSFHEATLLQL
                     LSSQIPPDAFPLLRNVMPAFIEWLERHHFSLSSRTWLKWLDVLAMEQSVSQADIKLAT
                     MATERFLQGSVSQEAYQQFGAMLELIVERASSFRNLSVLGELIELFLDSPVQDQATLT
                     SLWLSVQSFVSGIWTRLDPTARTVMRNLAADVLGEGAESVFPVEQDSCSADAEDELPD
                     LSGARVAIYSLTEGAARRAKRMLETLFPGIGVEISQAHTATDKLINQAKQADYFIFSA
                     GSATHQAFYAVSAQRRDLIYPTGKGAGSMLNAFITHVQQVSTVVV"
     gene            complement(5081..5611)
                     /locus_tag="RH288_002931"
     CDS             complement(5081..5611)
                     /locus_tag="RH288_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLD-like domain protein"
                     /protein_id="HDV4031970.1"
                     /translation="MEEQRQIFLHGPLGQRHLREILSAQFSGLILYPELIWLISPWMS
                     DFDVIDNRGGQWSFLDPSWGARMISFQELLATAVNNGCPLRIVTRKDTHSVVFIERLL
                     MRLSPDHDMQYLYHENLHAKGLLTKHFFLKGSMNYTWSGANVNDEHLLFSTNNTVISD
                     ALIEFSGQYTFGDTHD"
     gene            complement(5623..10059)
                     /locus_tag="RH288_002932"
     CDS             complement(5623..10059)
                     /locus_tag="RH288_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDV4031971.1"
                     /translation="MSTADLSLLHQALDLLEEREAELLVWGDTDGAFTHADIISLFTR
                     HLPYEDAESLLAELQKAAMLFSVPTSKGGTRYRTRMAEAVCLFRHQRQWFRNQPLQQA
                     RTLVADYRFVRRPRNYPKRELPAQTVLSKWVDVPWMNEIKRQALSRLIGDFFIAGFQE
                     RSTERILRAWHFHSHHARVKEATGTIVCAGTGSGKTLAFYLPALTSLLNDIQRDNAQR
                     VRTLALYPRKELLKDQFMETWSKCRELDNQALVLTGRKIRIGSFFGDTPFNHQYAMKD
                     KDKDMPFDLLRCTTPKCSGQMHWKAEDIKAKKEILRCSHCNHSVDSDEVILTRVSLMK
                     NPPDILFTTTEMLNQHLGNNQTNHLFGVGIDVTPPPVVLLDEVHTYVGNTGAQTAYLL
                     RRWMQLARSHPHFVGLSATLSDAERFFADLVGAHKKHVALIEPKFHEMEDEGAEYLLA
                     LRGDPVSQTALLSTTIQTSMLARRILDTKRKKSCGTWGQKTFVFTDDLDINNRLYHQL
                     CDAEGWRSRGQNLYVAKPPLASQRLETPKNSHKLTLAGQNWRIALDIGHSLDENDRAI
                     VARTSSQDVGVDPRAEVVIATASLEVGFNDPSVGMVIQHKAPRNVASYLQRKGRAGRS
                     RTMRPWMVAVLSEFGRDRVVYQRYEELINPEIKGQLLPMGNIHIQKMQAAMATLDWLS
                     MKIPGSNIWSLLNKPQTKRESLDHLDRMLHLITAVIEQHAWQLELEKYLFYALRITDE
                     QLQRVLWSPPRSIMMELLPTLKRQLTTQWSRMGQPEADRSTGRSPLPAFIPSALFSEL
                     NLPELEIHLERKFEKREHLPFIQGLKEFAPGRISKRYAVYSDNEADWLIPNNFVPAMN
                     CVSDVDFEIEQAFGNTWQPECVIECEGQPPIRVIRPMQVLTRALRFDQNLTEKSNSQL
                     YWHTRFNPDDQAVPLPIPTGPWAEILRSITFFTHQNMTPLDVTRYATHATASLRNKTK
                     QQAHVNFRWVEHGEPVGVGVRQWVDGARLRFTLPPNLLQRLRHDPAIQRALRTLYFQH
                     RIKREPRFEYDTFTADWIYECYLAAVTRELVTQSSLADSIAELKTPDGRRRLADIADT
                     LFQADNIFENCEDGEDDVESQELQQNLRNLFKETDILDMIDRHSAILTQDLSDDVDFQ
                     DWLQELLTTTLAGAVKQTSHLLLPDVDERGLVVDTELNDEVLDVWLTESEPGGCGIIT
                     RMEDVFHQDPVSVLNLFMRSFAVSDYEQIDYNLFEMLSRLSSSSELQEALNAIRQASS
                     HLQRRQANAHLRALLKAQGFALSHSFMSVLHTRVLRPGSQASHDAQMLAYLNAWRELE
                     DKAGYEIALNIFAHTQATQELPDASVIKVFERFCKIQGMLWQRGNAIRRSVLSYYNPF
                     KSGNNLTERLLLSSLFQQTACSISISESDWLAQLHHAITQHGFAELHIPREARHRIVE
                     VISLVQVTPIEYFGLHLYPRESAVDYQDGNLVLRFELAEALL"
     gene            complement(10063..10911)
                     /locus_tag="RH288_002933"
     CDS             complement(10063..10911)
                     /locus_tag="RH288_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000209821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031972.1"
                     /translation="MTTLRQQLAEMQKELDLSFQAGKASQIIDKCNLVCSKTNTIADK
                     FVLLKQQYSAQQQLPRGIAVTWNDEQRSELIAAANSVKSLMLQWRRWLKKQSVDNSGE
                     EENLADQEESPQESLGETLTASEEPTAYDIIQNDSLTHCVNQLGALHKDLSKELKDAW
                     NTWLEELHHQVHVDDKTLNFQKNTNKFDDIASDYERRRLDFENLTQSQPVSDEKIHQI
                     KALAEKLYSLRGMMKTDWPDVVQAFFNRINGPQNLRPTLSALTPEVLEWLTVEEMLDE
                     FVITRK"
     gene            complement(10908..14114)
                     /locus_tag="RH288_002934"
     CDS             complement(10908..14114)
                     /locus_tag="RH288_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031973.1"
                     /translation="MSIMEYWPSRKNIVQCIRNEAEELEDHVLLAVHEPMLLTRRDVN
                     ENHTILRDEDLFQQLLHTERAIPLIGRSGMGKSHLVRWLDCRFNMYLAENNKNEQWEI
                     VRIPKNASLRQVLLRILKNLTGEFFDNARMRVNEVTEQYPAKDLADLLLTMMAHQLQD
                     MQKAVKEEGQTLLAQGKDIPADRLAYMEAIIEEVENGICDLITDPNFKQNLLNPGHCI
                     FKLASRMSSGLKEGEEDHDKYELLPEDLYFIFEPDDLSARARRYLNHSQLHESDQVEA
                     RARAARVLNEAMHTSLKSLFKRLFTFNGGSFQELFQDIRKEFLRLNRRLVILVEDMAA
                     ISAIEDVLIDSLIEEAAPGGVQVLCPVHSVIAVTDNYPGYKRRQETLITRAGYEWVIE
                     NVDKDNNEDRIVSFCGRYLNAARFGSKELKKRPEQGKSLWPPVWHSDEIPDALEDFGY
                     SANQKFPLFPYNRSAILALADKHCRDSSGELIFNPRTIINRILLDILRDCRIEAEKTQ
                     FPPANFAGIHAVPEIEDKISQLVVSRVGSSVTLAAIWGYGIDSFDELRVKLPSSVAST
                     FGLDELAAQLNGKGPTMKSVEPVTKNAHETTGKTGSTPAGKKIDNPEFEPKEEAKYTA
                     KSELPFIRAVRAWVNDNVILPQEVARDLRTALNACYEIHAQPELFGMSSRPPLKEGRF
                     TLIFLPKAASNPSSIITNFYSEQDLTDPSRRVDVYNAAVALLRIQHYADLKQGFNYPE
                     AQEDYTRYQNFIQWWVPQATESAINHFRARNLRDALKKHLQKALLLGLVTGKEEPAEI
                     VNTLCLTQKGVGRTEGKSTGRTLTTAPSEICFRGIEATLHPHASARVAEARAQALVGW
                     DDARKAWLEQVAITEQGSGLGSSRALDADVIYSALKTVLKQPLGAEIERAALSVKQEL
                     ASTLKNVQLFANIKDSDDFLRQLNDWQTFIETVRAEHYPTGSAQYKPSSWLLGEIEAL
                     RTNSEESLATLNALLSIEKQKDSAKLWLEICQLDGDYVSRISSILAQWQLVQPKIAFT
                     LQQMNAKGDIQQLTLALNKVNDRLKTLASDIIASGVDQ"
     gene            complement(14111..14986)
                     /locus_tag="RH288_002935"
     CDS             complement(14111..14986)
                     /locus_tag="RH288_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4031974.1"
                     /translation="MSIINNANPGSGLILLPLIERVLQSAQEPLSQDTLLARYRPDNL
                     PANDNAWRKLKENLSFWCNLGLWPMLDGKMLPLEAGVRPLAHRLLICTIDACREKGVA
                     SGNDCEPLWRVLSCLLSLQQHSVGGREPLSPTIITNKVHKWLPGETINSNTEKLVREF
                     GRFLGFLELMPDGNYVTDPTRAIQYFLPEIFDDTHTLPAKIFMANMAEVMPMMDGGQY
                     RNSVHDVMQQEKDWIAPEGDNICTSTSVALQRLEISRRIILSIHSDDKDALSLHLPGG
                     KIRRVSQITLREDAE"
     gene            complement(14973..17453)
                     /locus_tag="RH288_002936"
     CDS             complement(14973..17453)
                     /locus_tag="RH288_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013367830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDV4031975.1"
                     /translation="MEEEWSRLQQALTTYFSQGVTFKDGIENQFLNRLIQIITDASAG
                     HGDIFAGYADALRAAHASGISEPWLPLPPELTDAPAPEWGMTKLPAVQQIQLAEESDL
                     ALTRATYQRKIRRNLLRPETDPALRRLLPEEPWLTHYQGFGQQAAIRTLLTSDNNCTL
                     LVNLPTSCGKSLLTQLQALSAPTNTLTLVIVPTVALAIEQADDMQKLLRGADQDHGGS
                     YVWIGGQDQPSRQAIKERIKAGTQRVLFCSPESVRSSLVPLLFELSRLNMIGAIVIDE
                     AHLIDQWGAEFRPDFQLIAPMIRSLKAMGKCRFRTLLLSATYSKSTRDILVEQFHDEN
                     SELIEVSANFLRPEPEYFVHHEANENAHRQRVEQLLMTLPRPLILYCTTRTDAEMWSA
                     RLNELGYWRIGIFHGQIDTNNRKKLISKWKNDQLDIMVATSAFGVGMNKKEIRSIIHA
                     AIPENIDRYYQDCGRAGRDGRSCQVHLVWHKAQMKTAKSLAVETLIGVEKGFARWKAM
                     FDDRKKSPIADYMISLNTKPVHIDHQGDKNEAWNRRTLLLMQRAGLIKLVFAEPKIPD
                     DLRDNLDDNNTQLIEWFESYYNHVHIRHCDDAHYSEAHWNTYVEKIRQSELNNRRAAF
                     TVMETWLEDPGKPLCKILQKFYEYQSHPPELTCGGCPGCRQKGKRAFSPTVGTDVQIL
                     RSEPKKKALFVGAEKKVYYNENMKLHSLLMELRVTLRSLITSGEYVFIRADRAVFLQL
                     ENNLDSLSHFWSAQKMTAPASDGPEIVIIPNTANAFPDLPMTRFERIIIAPEHLADPQ
                     FPHRTWCASAANALSLDSFIRQLQHVNN"
     gene            complement(17453..20560)
                     /locus_tag="RH288_002937"
     CDS             complement(17453..20560)
                     /locus_tag="RH288_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase SNF2"
                     /protein_id="HDV4031976.1"
                     /translation="MNVLPIGSLVISEQFEGIGKVVTVDSDTNNATVAFFESPAQPYA
                     RQMKVPLEQLTLTIPHEETVIYCIEPHSQRWTRARFGGSRPKGDFLVIFREDETTTLP
                     IDEIFVLNKAPDTPINPADFLALQANDAPFFFPYRQAFIETYIQQRAACRAMASISSS
                     AVELEPHQLAVVRRVLQDKNPKYILADEVGLGKTIEAGMVIREHALEATGHVSMLIAV
                     PAPLVSQWREELAERFQLKQLIIDASTALAGLRQNEATEGIVICSHCDGCTLIERGFT
                     PSLIAVDEVHQIASWPWSGDKDERYDFNLIAEGCRKAHYVLLLTGTPLHGHERNFLSM
                     LHCINPEAYQVDETHLQDFTELVKNRENLGGIFSGLVPSVSNVSLRRNLETLQQQFPE
                     DTVLMTLCQQLIPLIGTFSPNTPEREEGIRDIRRHLGENYRIHHRLLRNRRQVSLSFD
                     ETKNLNLNLLFPGLNGAEECRWYCDGLALDELIDEYRSLSLLPQNTQWAMSEDTYLFW
                     VDDLLSSPLCVMQRAKVHLGEAERTQEERDLLEHIVSTAKNELQAIDYKLAITLNEWL
                     QKNPTGKAIVFCDRPDLAQHLAIKLELLLEYPQELYQPGHPLMYLKPGSPIRILICDK
                     SGEDGLNLHGGLRLAVHYGLPRSCSRIEQRLGRLNRYSANLKGVKPVQSLILKNHADC
                     GLRNVWARILKDYIGVFNNTIASLQFVLDDYLENAWQNVYQEGPVALERVAREFPGEQ
                     GILANETHKINMQEKLLAMDDEIAEAAIFAQQISADDHLAVAQCNALTSWITRVLRFR
                     TTGTAEKGIKFQFELSDRSTGTLVDFKTFLTTCMLSFDKEGGNPPSTHLMSAERIPAI
                     DGTTVYPLRYGQPFVDTIWQLLNQDARGSSMAVLRVLPKPLNEPNYFFQSTWLVTHCQ
                     TQDTYAQRRIADELYPPRIVQHWLSSNGTPVINPQLLELLNGEYAKHETSQKFYADIN
                     LRPNLWQEIEELVSPDTWKEMVERVYTSDREQQQATFGEQARLQLMAVKAVVVCSRNL
                     LEEIV"
BASE COUNT         4966 a         5124 c         5245 g         5462 t
ORIGIN      
        1 tggtattgag tatttggctg acgcaaaaaa acaactgctc attataactt cccaaaaggt
       61 caatcgtagg ctaacggcat accttttcaa aacaaacaaa aatatggctc agtggttgag
      121 atgcaatatg cttatgctta atatcagtgt agcaaaatac attgtgaagg aatttacgtc
      181 aaaacaactc aatgatttaa atgagttatc tcaaaagtta acagaagaac tcaaagagtt
      241 acctgtgcgc gaagtgaaaa aaggaattcg tcgtagccaa gaggaagtta agtcattcat
      301 tttaaagctt atggaacaaa atcctagtgt cagtgcaaca catgcgttgc gtgaatttcg
      361 tgactcggga aattcatttg aggaaaaacg ttttcgggct gagtttaagg cccttagaga
      421 ggctaaacct taatgctact tgctgggatt tcatggtaga atccctcgtt ttttgagacg
      481 ttgcagtggt gtcacaggag agtaagttgt cgaagctaaa gtattttttc ccagatagtc
      541 aggattttat tgatcccagt ttcgacttct tccgcgaaac gcgtaacgaa catcgcgtgc
      601 gtcaacgtga cgatcattat ccgcatgagg ttttttctca tccttacgat ggtatgctgg
      661 tttctaaagc cgtagtagat ggtcttggtg gcggtgagag caaatatacc cgtgcccagc
      721 gtttacgtta tttccgtaat ggaatgaagc actttttccg tcttccagaa aatatggaaa
      781 ctatgggtga ttgcggagcc ttcacctatg ttaaccagga cgtcccccca taccgtgtgg
      841 aagaggtgat tgagttctac gaaacttccc gctttaacta tggcgtttct ctcgatcaca
      901 tcgtctttgg ttatgagagg ccaggggaag tattcagtgg cgaagtattg actgaatgtc
      961 gccgacgcca ggatatcact ctgaccctgg cacaagagtt tttaaacaag tctcaaaagt
     1021 cctgtttcac tccctttggt gttgcacatg gatggaataa aaactcctac cgtcagtctg
     1081 tagaggccct gctagccatg ggatacaaaa atatcaccat gggggggatg gtaccgttga
     1141 aaacgacgca gatccttgag accctcgaag aaattaaacc gctgctgaaa agtgatacac
     1201 gtgttcactt gcttggtatt gcccgtccag agagtttcgc cgactttatc aagtttggtg
     1261 tgaccagtat tgactcgaca acaccgctgc agcaggcctt caaagatcga aaaaataact
     1321 accatacgcc tgatggcccg gcctataccg ctgtgcgagt tcctcagttt gatgcgaatc
     1381 caagtttgag tcgcaaaata aaatccggcg tgattgatca ggatattgct cggcatctgg
     1441 aaaaggatgc catgaatgcc ctgttcgaat acgataaagg ggctttgccc cttgaaaaaa
     1501 ctcttgaggc agtactggct tatgaacgcc tgcattcagg tgaaaaagag gccaataaaa
     1561 tccgtgcgga ttatgaacgc acactgggtg aacgtccctg gaaacaatgc cagtgcaata
     1621 tttgccaagc tatcggtatc aacgtcatca ttttccgcgg agcagaacgt aaccgtcgcc
     1681 gcggtttcca taatattcag gtgttgtaca accgtttaca gcacacattg tcattacgct
     1741 cagaggaact gtcatgagtg aatatcgtgt tcccgccctg cgaatccgac agggtgagga
     1801 gaggcaactc tatagccttg cgatagaagg taaacagatt agcaaaattg cagcgatttc
     1861 gcgtattcgt cgcggtgaag agaatttggt tggttatcag cgtccagaag tacgtaacca
     1921 tattcgcgaa attcagcgct atattgagag taaaaacccg atgataccca acccggtgat
     1981 tatcgctttt gataagcgtg tgcgttttga accgcttaca gataatggcg acatggggca
     2041 tctggtgata cctttctccg aagataagga ttttgagaag cctgggttta ttgtggatgg
     2101 tcaacaacgt accgctgctt tgcgggatgc ggaaatcgac tcgtttatga tgccggtctc
     2161 tgcatttatc gctaatgatg cagaagagca acgcgagcag tttatgctgg ttaactccac
     2221 aaaacctctg cccaaaacgt tgttatacga attggcacca catacccatg gtcgtttgcc
     2281 atccgatctg caaatgcgta agtttccttc actgctgact caacgactaa acttcggcga
     2341 aggaccactt gcaggacgta tcaaaacggc aaccaatcct gatggggtta ttgctgacaa
     2401 ctcgatgatt aaaatgatcg atgccagtct tcgtgaggga gcattgtatc gattccgtga
     2461 cccgtcgaca ggtttggggg atgaagtgaa gatggtgaaa ctgctgaata acttctggtc
     2521 ggcggtggaa accgtgttta ccgatgattg ggacaaaaag ccacgctatt cccgcctatt
     2581 acacggcgtt ggtattcttg ctcttggtag tttgatggat gaaatcgatc aggttcatca
     2641 ggactataaa ggtgaacctg gctggactga gattccttcc tatactcgtt ttgtcgaaga
     2701 gttaaaccgc atcaagccac tttgtgcatg gagtagtggc gcgtggaact tcggtacgga
     2761 tattgatggt cagcccattg ttcgtaaatg gaatgaactg cagaacctgt cgaaagatat
     2821 ctcattagtg acggattatc tggtcaccag ttatatcaaa gcagcgaacg ccaatatata
     2881 aaaagggggc atttgcccct atttttatac cactactgtt gagacttgct gaacgtgcgt
     2941 aataaacgcg ttcagcattg acccggcacc tttacctgtt gggtagatta aatctctgcg
     3001 ctgcgctgag accgcgtaaa aagcctgatg agtggcgctg cctgccgaaa agatgaagta
     3061 atcagcctgt tttgcttgat taatcaactt atcggttgca gtgtgtgctt ggctgatctc
     3121 cactccgatc ccgggaaaca gcgtttccag catccgtttc gcgcgtcttg cagcaccttc
     3181 tgtcaagcta taaatcgcca ctctggctcc ggataagtcc ggcaattcat cttctgcatc
     3241 tgccgaacag ctatcctgct caaccggaaa tacactctct gcaccttccc ctagcacgtc
     3301 agccgccaag ttgcgcatca cggtacgagc agtcggatcc agtcgcgtcc atattccgct
     3361 cacaaaagac tgaacgctga gccacagcga ggtgagcgtc gcctgatcct gcaccggaga
     3421 atcaaggaag agttcgatca actcgcccag cactgacagg ttacggaacg aactggcgcg
     3481 ttcgacgatc agttccaaca tggctccgaa ctgttgatat gcttcctggc taacagagcc
     3541 ttgtaggaag cgctccgtcg ccatcgtggc cagcttgata tccgcctgac tgacgctttg
     3601 ttccatcgca agaacatcca gccactttag ccacgtcctg ctactcagac tgaaatgatg
     3661 acgctcaagc cattcaataa aggcaggcat cacgttacga aggagcggga acgcgtctgg
     3721 tggaatctga cttgatagta actggagcag cgtcgcttca tggaacgagt cagcgggcca
     3781 gttttcactt tccagcgcaa ccagttgcac aaggctgttg ctgtcgactt ctgactgaca
     3841 tagtcgggaa aaacaaatat cccagcccac gatttgcgga ttggtcagat ggcggatctc
     3901 ctcgatgagt gttttcagta gcggtaccgc catcgcttcc tctatcaact gctggtcaag
     3961 cgtgtggagc gtttgtgcgt agccgataat ctcctcttgc gttgcggtca gggaggtttg
     4021 taaatatgcc gcaagctgtt gcagcgtatc cgggaccgac gtcgtcgctg tcgtcgctga
     4081 cggactcact aagttgaacg gccgactagc ccaggtgtgc aatccattca accagtcggt
     4141 ttttaggcgt tctggcaacg cgttgagcag gtcgacttca ccaataagca tcactccagt
     4201 ggcccaagtt ttccacgccg caaagtcagt ttcatcttgg gataaaaaag gtatctgcgt
     4261 aaacagaggg tttagtgcca gacattgcgg gcgaagatcc gccggtgagg cttgcggata
     4321 cccatggctg tcgggtgtaa aatagcgctg ctggtatgct ttcagcagca tccgcatcag
     4381 ggttgtagga atgcgtcccc gaaccaaatc agcaagagaa tcgtgattca gcagtgtgtc
     4441 ccacttctct aacttacccg cctgctggag ttcgagcagc ataaggttac gtcgcgaaag
     4501 cgtaccgttg ttcttcagtt cctgtagtaa agcgtcgctt gtggcttcgt ctttttggct
     4561 attcgccaga atgaaatcac tcaagattcg cccgaagggg cgtttgaccg tgcgtacgat
     4621 tgatggcctg tcacgaaata ggacgataac gtcttttagc gcggcgaaaa cccgctcttt
     4681 tgctggttta tctttaagct ttgtgggcaa taattcgatc cggataaatc cggctggaca
     4741 gtgcgtcagc aacgccgttt cagacaggga cgtcgctccc tgtgcgggga caaaggtcac
     4801 ctttctgtca gcaataacat ctgcagaccc cagcctggca ttcaacacat tgctgagttc
     4861 ctgcgtggtg cgagctgtat ctgccgcggc aaaaaatacc cagcgatggg catcacacca
     4921 gggcagaatg agtggccact gagcatcagt cgcgctctcg taaagcggca gtaatacggc
     4981 ttttaagtct gcagggtagg cgttttcaac gttgtccagc aacctgtcca gcttcagtaa
     5041 atttccgttg ccaaagaagt cacgcagcca ttgaggaaca ttagtcatgg gtgtctccaa
     5101 aggtgtactg gccgctaaat tcaatcaacg catctgaaat caccgtatta ttggttgaaa
     5161 acaacagatg ctcatcgttc acgtttgcgc cgctccaggt gtaattcatg gagcctttca
     5221 gaaagaaatg tttggtcagc aatcccttag cgtgcaggtt ctcgtgatat aggtattgca
     5281 tgtcgtgatc gggcgataag cgcatcaata gtcgctcgat aaaaaccacg ctgtgcgtgt
     5341 ctttacgtgt cacgatacgt aacgggcaac cattgttaac ggcggtggcg agcaattcct
     5401 gaaagctgat catccgagct ccccatgaag gatcaagaaa actccactga ccgcctcggt
     5461 tatcaatcac gtcaaagtca ctcatccacg gagagatcag ccagatcagt tccggataga
     5521 ggatcaagcc actaaactgc gcgcttagga tttcccgcaa atgtcgctgg cccagtgggc
     5581 catgcaggaa aatttgtcgt tgttcttcca tttctgcgtt ccttacagta gcgcttcggc
     5641 cagttcaaaa cgtaacacca gattgccatc ctgataatcc acggcggatt cgcggggata
     5701 aagatgcaaa ccaaagtact caattggagt cacctgcacc agagagatca cttccacaat
     5761 acgatggcga gcctcgcgcg ggatatgcag ttctgcaaag ccgtgttggg taatggcgtg
     5821 atgtaactgc gctaaccaat cgctctcgct gatgctgatg ctacacgccg tctgttgaaa
     5881 cagtgagctt agcagcagtc gttcagtcag gttgttaccg gacttaaacg gattgtaata
     5941 gctgagaacc gaccgacgga tggcattgcc gcgctgccag agcattccct gaattttgca
     6001 aaagcgctca aaaactttaa tcacactggc gtcaggcagt tcttgcgtcg cttgggtatg
     6061 ggcaaaaata ttcagagcga tttcgtatcc ggctttatct tccaattccc gccatgcgtt
     6121 gagatatgca agcatctgcg catcatgtga cgcttggctg cccggacgta atacccgcgt
     6181 gtgcagcacc gacataaaac tgtgactaag tgcaaatccc tgcgccttta gcagcgctct
     6241 gaggtgggcg ttagcctggc gacgctgcag atgactgctg gcctgacgta tcgcattcaa
     6301 ggcctcctga agttcgctgg aagatgagag ccgcgaaagc atctcgaaca ggttgtagtc
     6361 gatctgctcg taatcgctga cggcaaaact acgcataaac agattcagta cggagaccgg
     6421 atcctgatga aaaacgtctt ccatacgggt aatgatacca cagccgccgg gttctgattc
     6481 ggtcagccag acgtccagta cttcgtcgtt tagttcggta tccaccacca gaccgcgttc
     6541 atcgacatcc ggcagcaaca ggtggctggt ttgtttgacc gctccggcca gcgtcgttgt
     6601 cagtaactcc tgtagccagt cctgaaaatc gacatcatca ctgagatcct gagtcaggat
     6661 cgcgctgtgc ctatctatca tgtccagaat gtcggtctct ttaaacaggt tgcgcaaatt
     6721 ttgctgcagt tcctgacttt caacgtcgtc ttcaccatcc tcgcaatttt caaagatatt
     6781 atctgcctgg aagagtgtgt ccgcgatatc agcgaggcga cgtcggccgt ccggagtttt
     6841 taattccgcg atagaatctg ccagagacga ctgtgtgacc agttcccgcg taaccgcagc
     6901 cagatagcac tcgtagatcc agtcagcggt aaacgtgtca tattcgaagc gtggttcacg
     6961 tttgatgcga tgctggaaat agagtgttcg cagtgcgcgc tgaatggccg ggtcatgccg
     7021 gaggcgttgc agcagattgg gtggcagcgt aaatctgagc cgtgcgccat ccacccactg
     7081 ccgcacgcca accccgacag gctcgccatg ctcgacccat ctgaagttca catgcgcctg
     7141 ttgcttggtt ttattgcgta atgaggctgt tgcgtgggtg gcgtaacgcg tgacatctag
     7201 aggtgtcatg ttctggtggg tgaagaacgt aatggagcgg aggatctccg cccacgggcc
     7261 ggtaggaatg gggagcggaa cggcctgatc gtctgggtta aaacgggtat gccagtacag
     7321 ttgcgagttg cttttctcgg tgagattttg atcaaatctc agcgcgcgcg taagcacctg
     7381 catcgggcga atgaccctaa tagggggctg accttcgcac tcgatgacac actcgggctg
     7441 ccaagtattg ccgaaagcct gctcaatttc aaaatcaaca tccgaaacgc aattcatcgc
     7501 cggaacaaag ttgtttggga taagccagtc tgcttcattg tcggagtaaa cggcatagcg
     7561 cttggaaatg cgccccggcg caaactcttt cagcccctga ataaagggca aatgttcacg
     7621 cttctcgaac ttccgctcga gatggatctc cagttccggc agattaagct cactgaatag
     7681 cgctgaagga ataaaggccg gcagtgggga acgtcccgtc gaacgatctg cctccggttg
     7741 gcccatccgc gaccattggg tcgtgagttg tcgttttaat gtcggcagca actccatcat
     7801 gatcgaacgg ggcggcgacc acagtacacg ctgaagttgc tcgtcagtga tgcgcaacgc
     7861 gtaaaacaga tacttctcca gctccagctg ccacgcatgt tgttcaatca cggcagtaat
     7921 caggtggagc atacgatcaa gatgatcaag agattctcgc tttgtctgcg gtttattcag
     7981 caatgaccag atattacttc cggggatctt catgctcagc cagtcaagtg tcgccattgc
     8041 cgcctgcatt ttctggatat ggatgttgcc cattggcaac aactgtcctt ttatctctgg
     8101 attaatgagc tcttcatagc gttgataaac gactcggtcg cggccaaatt cggataggac
     8161 agcgaccatc cacggacgca tggttcttga acgaccagca cgccctttgc gctgcaaata
     8221 ggaggcaacg ttacgtggcg ctttatgctg aataaccatg ccaacggagg ggtcgttaaa
     8281 gcccacctcc agcgacgcgg ttgcaatcac cacttccgct ctaggatcga ccccgacgtc
     8341 ctgactggac gtgcgggcaa cgatggctcg gtcattttcg tcaagtgagt gaccaatatc
     8401 cagcgcgata cgccagttct gtcctgccag tgtcagctta tggctgtttt tcggtgtttc
     8461 cagacgctga gaagccagcg gtggttttgc aacgtataag ttttgaccac gcgaccgcca
     8521 gccttcggcg tcacacagtt gatgataaag tcggttattg atatccagat cgtcggtgaa
     8581 gacaaaggtt ttttgccccc atgtcccgca tgattttttc cttttcgtat ccagaatacg
     8641 ccgagcgagc atgctggtct ggatagtagt agatagcaag gcggtttgcg agaccggatc
     8701 accgcgtaat gccagcagat attcagcccc ttcatcttcc atttcgtgga acttcggttc
     8761 gatcagagcc acatgttttt tatgtgcacc taccagatcg gcgaagaaac gttcggcgtc
     8821 actcagcgtt gccgaaagcc caacaaaatg agggtggctg cgcgcaagtt gcatccagcg
     8881 tcgcagtaga taggccgtct gtgcaccggt attccccaca taggtgtgta cttcatccag
     8941 caggactacc ggcggaggtg ttacgtcaat gccaacgcca aataggtgat tcgtttggtt
     9001 attccctagg tgctgattga gcatttcggt agtggtaaac aggatgtcag gcgggttttt
     9061 catcagcgag acgcgggtca ggattacttc gtcactgtct acgctgtgat tacagtggct
     9121 acaacgaaga atctcttttt tcgctttgat atcttctgct ttccagtgca tttgccccga
     9181 acatttcggc gtggtacaac ggagtaaatc aaagggcata tccttgtctt tatctttcat
     9241 tgcgtattga tggttgaacg gggtatcacc gaaaaaagaa ccaatacgga tcttgcgtcc
     9301 tgtcagtact agggcctgat tatcaagttc acgacattta ctccaggttt ccatgaactg
     9361 atctttaagc agttctttac gtggatacag tgccagcgtc ctgacccgtt gcgcattgtc
     9421 gcgctgaata tcattgagga gcgaggtgag tgccgggaga tagaacgcca gtgttttacc
     9481 actccccgta ccggcacaga caatggtccc ggtagcttct ttcacgcggg catgatgact
     9541 atgaaagtgc caggcgcgca aaatacgttc ggttgagcgt tcctgaaagc cggcaatgaa
     9601 aaagtcgccg atcagtcggg aaagcgcctg gcgtttaatt tcgttcatcc acggaacatc
     9661 gacccatttg ctcagcaccg tttgcgccgg aagttcacgc ttcggatagt tgcgcgggcg
     9721 acggacgaaa cggtagtcgg cgacaagcgt ccgggcttgc tgaagcggtt gattgcggaa
     9781 ccattgacgc tggtggcgga acaggcatac cgcttctgcc atacgcgtgc ggtagcgagt
     9841 tccccctttg ctggtcggga cgctgaaaag catggctgcc ttctgcagtt ctgccagtaa
     9901 cgactcggca tcttcgtacg gaaggtgccg ggtaaagagc gagatgatat cggcatgggt
     9961 aaatgcgcca tctgtatccc cccagaccag cagttctgct tcccgctctt cgagcagatc
    10021 cagcgcttgg tgcaggaggg acaaatcagc cgtagacata aattatttcc ttgtgatcac
    10081 gaactcatcc agcatctctt caaccgttaa ccactcaagc acctcaggcg taagggcgct
    10141 taacgtcggg cgcaagttct gcgggccatt aatgcgattg aaaaatgcct gaaccacgtc
    10201 aggccagtcc gttttcatca tgccgcgcag ggaatacagt ttctcggcta gcgctttaat
    10261 ttggtgaatc ttttcatcgc tgactggctg gctctgcgtt aagttttcga aatccagacg
    10321 tcgacgctcg tagtcggagg cgatatcatc aaatttattc gtatttttct gaaaattcag
    10381 agttttgtca tcgacgtgaa cttgatgatg taactcttcc agccatgtat tccaagcatc
    10441 ttttagttct ttgcttaggt ccttgtgcag ggcgccgagt tggttgacgc aatgggtcaa
    10501 ggaatcattc tggatgatgt cgtaggcagt aggttcctct gaggcggtca gagtctcacc
    10561 cagagattcc tgtggtgact cttcctgatc tgcaaggttc tcctcctcgc cagaattgtc
    10621 taccgactgt tttttcagcc agcgtctcca ctgcaacatg agacttttga cgctgttcgc
    10681 ggcagcgatc agttcgctac gctgctcgtc attccaggta accgcaatgc cccgcgggag
    10741 ttgttgctgg gctgaatatt gctgtttaag caatacaaac ttatctgcaa tggtgttagt
    10801 tttgctgcac accagattac atttatcgat gatttgtgag gccttaccag cctgaaagct
    10861 aagatcgagt tctttttgca tctcggccag ttgttggcgt aaggtggtca ttgatcaact
    10921 ccagaggcga tgatatcgct cgcaagtgtt tttagacggt cattcacttt attcagagca
    10981 agagtcagtt gctggatatc ccctttggca ttcatctgct ggagtgtgaa cgcgatcttg
    11041 ggttgtacca gttgccattg cgcaagtatg ctgctgattc ttgaaacgta gtcaccatca
    11101 agttgacaga tctccagcca caatttcgca ctatctttct gtttttcaat ggaaagtaac
    11161 gcatttaatg tcgccagact ctcctcggag ttggttctga gagcttcaat ttcccccagc
    11221 agccacgaag atggcttgta ctgagcgctg ccagtggggt agtgctcggc ccgcacagtc
    11281 tcaataaacg tctgccagtc gttcagttgt ctgaggaaat cgtcactatc tttgatgttg
    11341 gcaaagagct gaacattttt taacgtgctg gcaagttcct gtttgacgga gagcgccgca
    11401 cgttcaattt ctgcgccaag cggctgtttt aacactgttt tcagcgcaga atatattaca
    11461 tcggcatcca gcgcacgact gctgcccaag cctgagcctt gctccgtgat ggcaacctgt
    11521 tcaagccacg cttttctggc atcatcccat cctacgagcg cctgcgccct agcttcggcg
    11581 actctggcac tggcgtgcgg atgcagtgtt gcctcaatcc ctctgaaaca gatctcggaa
    11641 ggagcggtcg tcagcgttcg accggtactt ttaccttcag ttcttccgac gcctttctgg
    11701 gtgaggcaga gggtattgac gatttccgcc ggttcttctt taccggtcac caggccaagc
    11761 agcagagctt tttgcagatg ctttttcagc gcatcccgta agttacgcgc ccggaagtga
    11821 ttaatggcac tttccgtagc ctgcggtacc caccactgga tgaagttttg atagcgagta
    11881 tagtcttcct gcgcctctgg ataattaaaa ccttgcttta aatcggcgta atgctggata
    11941 cgtaacaggg ctaccgcggc gttatacaca tctacccgtc gggaaggatc ggtcaggtcc
    12001 tgctcagagt aaaagttcgt aataatactt gaggggttag atgccgcttt tggcagaaaa
    12061 atcaacgtaa aacgaccttc tttcagcggt ggtcgagaag acataccaaa caactctggc
    12121 tgtgcatgaa tttcataaca agcgttcagt gccgtacgca aatcacgggc aacctcctgc
    12181 ggcagaatga cattatcatt cacccatgca cggacagccc tgataaaggg tagttcggat
    12241 ttggcagtgt attttgcctc ttctttcggt tcgaactccg gattgtcaat ctttttaccc
    12301 gccggcgtac tgcctgtctt gccagtcgtt tcgtgtgcgt tctttgttac tggttccacc
    12361 gatttcatcg tgggaccttt gccattcagt tgtgcggcta gctcatcgag gccaaaggta
    12421 ctcgcaacgc tacttggcag ttttacgcgt agttcatcaa aagaatcaat gccatatccc
    12481 cagatggcgg caagtgtcac cgaactgcca acccgactga caaccagttg tgaaatcttg
    12541 tcttcgatct cgggaacggc atgaattcca gcgaaatttg ctggcgggaa ctgtgttttt
    12601 tccgcttcta ttcggcaatc gcgtagaata tctaacagga tgcggttaat gattgtgcgc
    12661 gggttaaaaa tcaactcgcc gctgctgtcg cggcaatgct tatccgccaa tgccagaatg
    12721 gcactacggt tatacgggaa tagcgggaat ttctgattgg cagaataacc aaaatcctct
    12781 agtgcatcag ggatctcatc actgtgccat acaggtggcc acagagactt accttgctca
    12841 ggacgttttt ttaactcctt tgatccaaag cgtgcggcgt tcagatagcg accacagaac
    12901 gagacaatac gatcttcgtt attgtcttta tcgacgttct caatgaccca ctcgtagcca
    12961 gcacgtgtga ttaacgtttc ctggcggcgt ttatagccag gataattgtc ggtgactgca
    13021 atcactgagt ggacaggaca gagaacttgc acgccgccag gtgccgcttc ttcgatcaga
    13081 ctgtcgatca gaacatcttc aatagcggaa atcgccgcca tatcttctac cagaatcacc
    13141 agacgacgat taagtcgtag aaactccttg cggatgtcct gaaaaagctc ctgaaaagat
    13201 cctccattga aggtgaacag gcgcttgaaa agtgatttca gcgaggtatg catggcttca
    13261 ttgagcacgc gcgctgctcg ggcacgcgcc tccacttggt ctgactcatg cagttgagaa
    13321 tggttcagat agcggcgtgc acgcgcggac agatcgtcag gttcaaagat aaaatagaga
    13381 tcttccggaa gaagttcata tttatcatga tcttcttctc cttctttcag accactactc
    13441 atccgactgg caagtttgaa aatacagtgg cctggattca gaagattctg tttgaagtta
    13501 gggtcggtga tcagatcaca gataccgttt tcgacctctt caatgatagc ttccatatag
    13561 gcgagtcggt ctgcaggaat gtctttacct tgcgccagca atgtttgacc ttcttccttg
    13621 accgcttttt gcatgtcctg caactgatgg gccatcatgg tcaacagtag gtctgccaga
    13681 tctttcgctg ggtactgttc tgtcacttca ttaacgcgca tgcgtgcgtt gtcgaaaaat
    13741 tcccccgtca aattttttag gatgcgtaaa agcacctgcc gtagactggc gtttttgggt
    13801 atccggacaa tttcccattg ctcattcttg ttgttttccg ctaggtacat gttgaatcgg
    13861 cagtctaacc agcgcaccag atgtgatttc cccatccccg agcggccaat cagtgggatc
    13921 gcgcgctccg tatgaagtaa ctgctggaac aggtcttcat cacgcaatat tgtatgattt
    13981 tcattgacgt cgcgtcgggt cagtagcatc ggttcatgta cggccagaag cacatgatcc
    14041 tctaattctt ctgcttcatt gcgaatgcat tggacgatat ttttcctgga tggccaatat
    14101 tccattatgc tcattctgca tcctctctta gcgtgatttg gctaacccgg cgaattttac
    14161 cgccaggtaa gtgaagtgat aaggcgtctt tatcatcact gtggatggag aggataatgc
    14221 gtctactgat ttcaagtcgt tgcagcgcaa cagatgtgct ggtgcagata ttgtcacctt
    14281 ccggtgcgat ccagtctttt tcctgctgca tcacgtcatg aacggagttt ctgtactggc
    14341 ccccgtccat catcggcatg acctccgcca tgtttgccat aaagattttg gcgggaaggg
    14401 tatgcgtatc gtcaaagatc tccggcagaa aatattggat ggcccgggta gggtcggtga
    14461 cataatttcc gtccggcatt aactcgagaa aaccgagaaa acgaccaaat tctctcacta
    14521 gtttttcggt gttgctattg atggtttcgc caggtaacca tttatgcact ttgttggtga
    14581 tgatcgtagg ggaaagaggt tcccggcccc cgaccgagtg ttgctgaagg ctcaacaagc
    14641 aactcagtac ccgccacaac ggttcgcaat cattcccact ggcaacgcct ttttcacgac
    14701 aagcatcaat cgtacagata agcaaccgat gcgccagtgg acgcacacct gcttcaagcg
    14761 gtaacatctt tccgtcgagc atcggccaga gtcccagatt gcaccaaaag ctcaggttct
    14821 cttttaattt tctccacgcg ttatcgttag cgggcaggtt atcaggacga tagcgggcga
    14881 gcagtgtgtc ctgagacaac ggttcctgtg cgctttgcag aacgcgttca atcaaaggaa
    14941 gcagtatcag tccgcttcct gggtttgcgt tgttaattat tgacatgttg tagttgcctg
    15001 ataaaagagt ccagcgacag cgcattagcg gcacttgcgc accatgttcg atgtgggaac
    15061 tgaggatcgg cgagatgctc aggtgcaata ataattcgct caaagcgcgt catgggtaga
    15121 tctgggaacg cattagccgt gttagggatg atcacgatct ctggtccatc cgatgcaggt
    15181 gctgtcattt tctgtgcgct ccagaaatgc gaaagcgaat ctaggttgtt ctctagttgc
    15241 aggaacactg ctctgtctgc acgaataaac acgtattcgc cagaggtgat cagtgatcgc
    15301 aacgtcacac gaagttccat caacaacgaa tgtaacttca tattttcgtt gtaataaact
    15361 ttcttttccg cacctacgaa gagtgctttt ttcttcggct cggaacgtaa aatttgtaca
    15421 tctgtgccca cggtgggcga aaacgccctt ttccctttct ggcgacatcc cggacaacca
    15481 ccacaggtta actcgggagg atggctctga tattcataga atttctgcag aattttacac
    15541 agtggtttgc caggatcctc caaccacgtt tccattaccg taaaggctgc ccggcggtta
    15601 ttcaactcgg actggcggat cttctccaca taggtgttcc agtgcgcttc tgaataatgc
    15661 gcatcgtcac agtgacggat atgtacgtgg ttatagtagc tttcgaacca ttcaatcagt
    15721 tgcgtgttgt tgtcatccag attatctcgc aggtcgtcag gaattttcgg ttcagcaaag
    15781 accagtttga tgagtccggc tctttgcatt aacagcaacg tccgacgatt ccaagcttcg
    15841 tttttatcgc cttggtgatc gatatgaacg ggcttggtgt tcagtgaaat catgtagtca
    15901 gcgatcgggc ttttcttacg atcgtcaaac attgctttcc agcgggcaaa acctttttct
    15961 acgccaatca gcgtctcaac ggccagcgat tttgccgttt tcatttgcgc cttatgccat
    16021 accagatgca cctggcagga tctgccgtca cgcccagcac gtccacagtc ctggtaatag
    16081 cggtcgatat tttccggaat agcagcatga atgatgctgc ggatttcctt tttattcatc
    16141 cctaccccaa aggcagaggt agcgaccatg atatcgagtt ggtcattttt ccattttgaa
    16201 atcaatttct tgcgattgtt tgtgtcaatt tgaccgtgga atatgccgat tcgccagtag
    16261 cccagttcgt tcagacgggc agaccacatt tccgcatctg tgcgggtagt gcaatacaaa
    16321 atcagcgggc ggggtaaggt catcagaagt tgttcgaccc gctgacgatg cgcgttttca
    16381 tttgcctcat gatgcacaaa atattccggc tctgggcgta ggaaattagc tgatacttca
    16441 atcagttcac tgttttcatc atggaactgc tcgaccagaa tgtcgcgggt acttttgctg
    16501 taagtcgccg aaagcagcag cgtacgaaaa cggcatttgc ccatggcttt cagtgagcga
    16561 atcatagggg caattagctg aaagtcaggg cggaactctg cgccccattg atcgatcaaa
    16621 tgcgcttcgt ctatgacaat cgcgccaatc atattcagtc tggaaagctc aaacagcaac
    16681 ggaaccaaag aagagcgaac ggattctggg gaacagaaga gaacacgctg tgttcccgct
    16741 ttgattcttt ccttaattgc ctgacgcgag ggctgatctt ggcctccgat ccaaacataa
    16801 cttccaccat gatcttggtc agcaccgcga agcagttttt gcatatcgtc agcctgctca
    16861 atcgcgaggg cgacagtggg gacgatcacc agcgtgaggg tgtttgtcgg tgcgctgagc
    16921 gcctggagtt gggtgagcag acttttaccg caactggtgg gcagattaac cagcaatgta
    16981 cagttattat cagacgttag cagcgtccgg atggcggcct gttgaccgaa tccctgatag
    17041 tgagtcagcc atggctcttc gggtaacagg cgcctcagtg ccggatcagt ctcggggcgc
    17101 agcaagttcc tgcgtatctt acgctgatag gtggctctgg tcagcgccag gtccgactct
    17161 tcagccagtt gaatttgttg cacggcaggc aactttgtca tgccccactc aggtgccgga
    17221 gcatcggtca gttctggcgg caggggtagc cacggctcgc taataccact cgcgtgagcg
    17281 gcacgtaacg catcggcgta gccggcaaaa atgtcaccat gacctgccga ggcatcggtg
    17341 atgatctgaa tcagtctgtt cagaaactga ttttcgatgc catctttaaa ggtgacccct
    17401 tgactaaaat aggtggttag cgcctgctgc aggcgtgacc attcctcttc catcagacga
    17461 tttcctctaa tagatttctg ctgcacacca ccacggcttt cacggccatt aactgaagtc
    17521 tggcttgttc gccgaaggtt gcctgttgtt gttctcggtc actggtatag actcgttcca
    17581 ccatctcttt ccacgtgtcc ggtgagacaa gttcttcgat ttcttgccaa agattagggc
    17641 gcagatttat atctgcatag aatttctgcg atgtttcatg tttggcgtac tcgccattga
    17701 gcagttccag caactgcgga tttatcaccg gtgtaccatt agaggacagc cagtgttgca
    17761 caattcgcgg cgggtacaac tcgtctgcaa tacggcgttg tgcgtaggta tcctgcgtct
    17821 ggcaatgggt gacaagccaa gttgactgaa agaagtaatt gggctcattc agtggcttgg
    17881 ggagcactcg cagtaccgcc atggaactgc ctcgggcatc ttggtttaac agttgccaga
    17941 tcgtatcgac aaatggctgc ccataacgca gcgggtaaac ggttgttccg tcgatcgccg
    18001 gaatgcgttc agcgctcatc agatgcgttg acggtgggtt gcccccttct ttatcgaagc
    18061 tgagcatgca ggtggtgaga aaggttttaa aatcgaccag cgtccctgtg ctgcgatcag
    18121 agagttcgaa ctgaaacttg ataccttttt ctgcagtgcc ggtggtgcga aaacgtagca
    18181 cacgcgtgat ccaacttgtc agtgcattac actgcgctac tgcaagatga tcgtcagcgc
    18241 tgatctgttg cgcaaaaatc gccgcctctg caatctcatc atccatcgcc agcagctttt
    18301 cctgcatgtt aattttatgc gtttcattgg ccagaatgcc ctgttcgcca gggaattctc
    18361 tggcaacacg ttcaagggcc accgggcctt cttggtagac attttgccac gcattttcta
    18421 gataatcgtc gaggacgaac tggaggctgg cgattgtgtt attaaatacg ccaatatagt
    18481 ctttcagaat gcgggcccac acgttgcgta atccacagtc ggcgtgattt ttcaggatca
    18541 gactctggac aggttttacg cctttcaggt ttgcactgta cctgttcaga cgaccaaggc
    18601 gctgttcaat acgactacaa gagcgcggta aaccgtagtg aacggctagt cgcagccccc
    18661 catggagatt cagaccatct tcgccgcttt tatcgcaaat taggatccga atagggctgc
    18721 cgggtttgag gtacatcaag ggatgacccg gctgatagag ttcctggggg tactccagca
    18781 gtagttcgag ctttattgcc aagtgttggg caagatccgg acgatcgcag aagacgattg
    18841 cttttcctgt cggattcttt tgcaaccact cattcagtgt gatggcaagc ttgtaatcaa
    18901 tggcctgtag ttcatttttt gcagttgaaa caatgtgctc taacagatct cgttcttcct
    18961 gagtgcgttc cgcttcaccc aaatgtactt tagcgcgttg cataacacag agtgggctgg
    19021 ataggagatc gtcaacccag aagaggtacg tgtcttcact cattgcccac tgcgtattct
    19081 gcggcagtaa agataatgaa cgatactcat caatcagttc gtctaatgct aacccatcgc
    19141 aataccagcg gcactcctct gctccattta gcccaggaaa cagaaggttt agattgaggt
    19201 ttttcgtttc atcgaagctg agtgaaacct gacggcgatt acgcaacagt cgatgatgaa
    19261 tgcgatagtt ttcccccaag tgccggcgaa tatcccggat cccttcttca cgctccggcg
    19321 tattggggga gaacgtccca ataagcggaa tgagttgctg gcagagcgtc atcagaacag
    19381 tatcttctgg gaactgctgc tgcagtgttt ccagattacg acgtaagctg acgtttgaga
    19441 cggaaggtac taaccccgag aagatcccgc caaggttttc gcgatttttg actagttcgg
    19501 taaagtcttg cagatgggtc tcatccactt ggtaggcttc cggattaata cagtgcagca
    19561 tcgacaagaa gttcctttca tgcccatgca gaggggtccc cgtgagtaac agaacgtagt
    19621 gggctttccg gcacccctct gcgatcaggt tgaagtcata acgttcatct ttatctcctg
    19681 accacggcca agaggcaatc tggtggacct catctactgc gataagtgaa ggggtgaatc
    19741 cccgttcaat cagggtacag ccatcgcaat gactgcaaat cacgatgcct tccgtggcct
    19801 cattttgtcg caaacctgcg agggccgtcg aagcatcaat aataagttgt ttcagttgaa
    19861 aacgttcagc cagttcttcc cgccactggc taactagtgg tgccggaacc gcaataagca
    19921 tgctgacgtg gccagttgct tctaacgcgt gttcacggat gaccattcct gcttcgatgg
    19981 ttttccccag cccaacctca tcggccagaa tatacttggg gtttttatcc tgaagtacac
    20041 ggcgtactac cgccaattgg tggggttcga gttcaacggc actactagaa atggatgcca
    20101 tcgcgcggca tgcagcgcgt tgctggatgt aggtttcaat aaaggcttgg cggtaaggga
    20161 aaaagaacgg tgcgtcatta gcttggaggg caaggaaatc tgcagggttt atcggggtat
    20221 ccggcgcttt gttcagaaca aaaatttcgt cgattggcag cgtcgtagtt tcatcttcgc
    20281 gaaagatgac gagaaaatcc cctttggggc gcgatccgcc aaaccgggct ctagtccatc
    20341 gttggctatg tggctcaatg caataaatta ccgtctcttc gtgcgggatt gtcagggtga
    20401 gttgttctaa aggaactttc atttgtcgtg cataaggttg agccggtgac tcaaaaaaag
    20461 cgaccgtggc gttatttgta tcactatcga cggtgacaac tttaccgatg ccttcaaatt
    20521 gctcagagat aaccagtgac ccgatgggta atacgttcat cctcacatcc ttgaattgtt
    20581 tcttataatc acatttgctc aaaaacaacc aaagacagac cgaaaatgtt actttgctat
    20641 gcctgagcga catgcttata agtgcattga tttgagtatt atgatcagga tactgagata
    20701 attctcatat tcaaggggga aagtagaaaa agatcaatga gatgttggct tgtgtagggg
    20761 agatttcagc gatatcaatt ttatctgtta caatgag
//
LOCUS       DAPHKZ010000076        20470 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.076, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000076 DAPHKZ010000000
VERSION     DAPHKZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20470
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.076"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            304..1170
                     /gene="folD"
                     /locus_tag="RH288_002938"
     CDS             304..1170
                     /gene="folD"
                     /locus_tag="RH288_002938"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HDV4031977.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQDE"
     gene            1172..1384
                     /gene="ybcJ"
                     /locus_tag="RH288_002939"
     CDS             1172..1384
                     /gene="ybcJ"
                     /locus_tag="RH288_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HDV4031978.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     gene            1492..2013
                     /locus_tag="RH288_002940"
     CDS             1492..2013
                     /locus_tag="RH288_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDV4031979.1"
                     /translation="MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLS
                     FNFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTAYGHQVIISELMWVWLP
                     GMLLMGMLWWRRR"
     gene            complement(2049..3434)
                     /gene="cysS"
                     /locus_tag="RH288_002941"
     CDS             complement(2049..3434)
                     /gene="cysS"
                     /locus_tag="RH288_002941"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDV4031980.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     gene            3608..4102
                     /gene="ppiB"
                     /locus_tag="RH288_002942"
     CDS             3608..4102
                     /gene="ppiB"
                     /locus_tag="RH288_002942"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HDV4031981.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     gene            4105..4827
                     /gene="lpxH"
                     /locus_tag="RH288_002943"
     CDS             4105..4827
                     /gene="lpxH"
                     /locus_tag="RH288_002943"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HDV4031982.1"
                     /translation="MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFE
                     AWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     gene            4945..5454
                     /gene="purE"
                     /locus_tag="RH288_002944"
     CDS             4945..5454
                     /gene="purE"
                     /locus_tag="RH288_002944"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDV4031983.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRNAQTDEVL
                     ENPDPRGAA"
     gene            5451..6518
                     /gene="purK"
                     /locus_tag="RH288_002945"
     CDS             5451..6518
                     /gene="purK"
                     /locus_tag="RH288_002945"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDV4031984.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAE
                     RSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRADETEQLPAECYGECIVEQGINFSG
                     EVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NNPSVMINLIGSDANYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEA
                     LIPLLPPEYASGVIWAQSKFG"
     gene            complement(6713..7606)
                     /locus_tag="RH288_002946"
     CDS             complement(6713..7606)
                     /locus_tag="RH288_002946"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDV4031985.1"
                     /translation="MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEETLAGEAGTCISL"
     gene            complement(7603..8418)
                     /locus_tag="RH288_002947"
     CDS             complement(7603..8418)
                     /locus_tag="RH288_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDV4031986.1"
                     /translation="MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWMLRRAQFDALCGGLCGNERPQVVAQGIRLRRFTVKQPQRYCLLRITPP
                     AHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRQFFACSDNLQLVTTAVSVSYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP"
     gene            complement(8429..9688)
                     /locus_tag="RH288_002948"
     CDS             complement(8429..9688)
                     /locus_tag="RH288_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009029994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDV4031987.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAR
                     AVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     gene            complement(9698..11365)
                     /locus_tag="RH288_002949"
     CDS             complement(9698..11365)
                     /locus_tag="RH288_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HDV4031988.1"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKA
                     LLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQAL
                     TQVRRWDSACQKLPDASLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLK
                     SRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK
                     ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAITPASSGFIC
                     GLYTGGTLAAEAAGLLAGHLGVEADDTHHHGMMLDADGHQIIDLGDDFYTVGRPHPMI
                     DPALRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYA
                     IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIRPLSPATQQHTPSLL
                     ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ"
     gene            11682..12731
                     /gene="allD"
                     /locus_tag="RH288_002950"
     CDS             11682..12731
                     /gene="allD"
                     /locus_tag="RH288_002950"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HDV4031989.1"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSS
                     ELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNLFAQ"
     gene            12753..13988
                     /gene="allC"
                     /locus_tag="RH288_002951"
     CDS             12753..13988
                     /gene="allC"
                     /locus_tag="RH288_002951"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HDV4031990.1"
                     /translation="MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFK
                     KRMAASGLETRFDEVGNLYGRLNGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKEL
                     VATLTELCEREKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     gene            13999..14784
                     /gene="allE"
                     /locus_tag="RH288_002952"
     CDS             13999..14784
                     /gene="allE"
                     /locus_tag="RH288_002952"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HDV4031991.1"
                     /translation="MGYLNNVTGYREDLLANRAIVKHGNFALLTPDGLVKNIIPGFEN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFA
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     gene            complement(15012..16157)
                     /gene="glxK"
                     /locus_tag="RH288_002953"
     CDS             complement(15012..16157)
                     /gene="glxK"
                     /locus_tag="RH288_002953"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HDV4031992.1"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADG
                     GEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPE
                     KRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQA
                     LAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARCAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAV
                     NLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     gene            complement(16179..17480)
                     /locus_tag="RH288_002954"
     CDS             complement(16179..17480)
                     /locus_tag="RH288_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HDV4031993.1"
                     /translation="MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     gene            complement(17537..18898)
                     /gene="allB"
                     /locus_tag="RH288_002955"
     CDS             complement(17537..18898)
                     /gene="allB"
                     /locus_tag="RH288_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HDV4031994.1"
                     /translation="MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVM
                     DASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVF
                     TEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGG
                     IAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQ
                     PNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILK
                     HQQ"
     gene            complement(18958..20412)
                     /locus_tag="RH288_002956"
     CDS             complement(18958..20412)
                     /locus_tag="RH288_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
                     /protein_id="HDV4031995.1"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLIFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGIGPIFDYIPSG
                     IQKAENGGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFVVMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIHFMEPLS
                     RVSWFVGVIVAFAAYALLKKRTTAEKTGEQKTIG"
BASE COUNT         4989 a         5602 c         5175 g         4704 t
ORIGIN      
        1 gcataatata ttcaacacaa atatagacct gaagcggtaa attactaggc tgaaaattct
       61 ttttatattg tcaggtattt cttaaattat cttaatcctt agacaaggaa ataaatcagt
      121 tccagattta caacgccatc atggacgaaa aatgaagctt tcagtctcag cgacggtgcg
      181 cctcaccttc gcaagaggtc gcttcacgcg ataaatctga aacgaaacct gacagcgcgc
      241 cccgcttctg acaaaatagg cgcatcccct tcgacctacg taacagatgg aatcctctct
      301 ctgatggcag caaagattat tgacggtaaa acgattgcgc agcaggtgcg ctctgaagtt
      361 gctcaaaaag ttcaggcgcg tattgcagcc ggactgcggg caccaggact ggccgttgtg
      421 ctggtgggta gtaaccctgc atcgcaaatt tatgtcgcaa gcaaacgcaa ggcttgtgaa
      481 gaagtcgggt tcgtctcccg ctcttatgac ctcccggaaa ccaccagcga agcggagctg
      541 ctggagctta tcgatacgct gaatgccgac aacaccatcg atggcattct ggttcaactg
      601 ccgttaccgg cgggtattga taacgtcaaa gtgctggaac gtattcatcc ggacaaagac
      661 gtggacggtt tccatcctta caacgtcggt cgtctgtgcc agcgcgcgcc gcgtctgcgt
      721 ccctgcaccc cgcgcggtat cgtcacgctg cttgagcgtt acaacattga taccttcggc
      781 ctcaacgccg tggtgattgg cgcatcgaat atcgttggcc gcccgatgag catggaactg
      841 ctgctggcag gttgcaccac tacagtgact caccgcttca ctaaaaatct gcgtcatcac
      901 gtagaaaatg ccgatctatt gatcgttgcc gttggcaagc caggctttat tcccggtgac
      961 tggatcaaag aaggcgcaat tgtgattgat gtcggcatca accgtctgga aaatggcaaa
     1021 gttgtgggcg acgtcgtgtt tgaagacgcg gctaaacgcg cctcatacat tacgcctgtt
     1081 cccggcggcg ttggcccgat gacggttgcc acgctgattg aaaacacgct acaggcgtgc
     1141 gttgaatatc atgatccaca ggatgagtaa catggcgaca ttttctttag gtaaacatcc
     1201 gcacgttgag ctgtgcgact tgctgaaact ggaaggctgg agcgaaagcg gcgcgcaggc
     1261 gaaaatcgcg attgccgaag gccaggtgaa agtcgacggt gcggttgaaa cgcgcaaacg
     1321 ctgcaaaatc gtcgccggtc agacagtgag ttttgcaggt cacagcgtac aggttgttgc
     1381 ctgatccctt tcccggcctg tatcaacagg ccggttctct tttcagactt ttgccctcta
     1441 cgccccgttc atccatgctg atagcatcga cattttgccg aagcgaccat catgccaacc
     1501 gttattacgc acgccgccgt tcccctatgc attggtttag ggttgggttc gaaagtcatc
     1561 cctccgcgcc tgttatttgc cggaatcatc ctggcgatgc tgcccgatgc cgacgtcttg
     1621 tcgtttaatt ttggcgttgc ttacggcaat gtttttggtc atcgcgggtt tacccattcg
     1681 ctggtgtttg cgtttgttgt cccgctgtta tgtgtgctga ttggacgtcg atggttcagg
     1741 gctgggctga ttcgctgctg gctgttttta accgtctcgt tgctatcgca cagcttgctg
     1801 gattcggtaa ccactggcgg taaaggggtt ggctggctgt ggccgtggtc agatgaacgc
     1861 tttttcgctc cctggcaggt gattaaagtc gcgccgtttg cattgtctcg ttacaccaca
     1921 gcgtacgggc atcaggtgat tatttctgaa ttgatgtggg tgtggttgcc ggggatgcta
     1981 ctgatgggaa tgttgtggtg gcgcagacga taaccggatg cgaaaactcg catccggcaa
     2041 tagcgcaatt acttacgacg ccaggtggtc ccttgcgggc catcttccag cacgatcccc
     2101 atctcattaa gacggtcacg cgccgcatct gccgccgccc agtctttcgc tttacgggca
     2161 tccagacgct gttgaattaa cgcttcaatc tcagccactt cgctgtcgtc tgcctgcgcg
     2221 ccgctttgca ggaacgcttc cggttcttgc tccagcaggc ccaatacggc ggaaagttta
     2281 cgcaggtgag atgccattgc attcgccgct gccatatctt ctgctttcag acggtttact
     2341 tcacgcgcca tatcaaacag cacggaatag gcttccgggg tgttgaaatc gtcgtccatc
     2401 gcttcaataa agcgcgcttc aaacgcttcg ccaccggcag gcgcaacggt tttatctgtg
     2461 ccgcgcagcg cagtgtagag acgctccagc gccgcacgcg cctgcttcag gttctcttcg
     2521 ctatagttca gctggctgcg atagtggccc gacatcagga agtaacgcac ggtttccgcg
     2581 tcgtagtatt tcagcacatc gcgcacggta aagaagttac ccagcgattt ggacatcttc
     2641 tcgcggtcaa ccatcaccat ccccgagtgc atccagtagt tcacatactg accatcatgg
     2701 gcacaggtgg actgcgcgat ttcgttttcg tggtgcggga acatcaggtc tgaaccgccg
     2761 ccgtggatat caaagtggtt acccagctgc ttgcagttca ttgccgaaca ttcaatgtgc
     2821 cagccaggac gacccgcgcc ccacggagac ggccagctcg gttcgccctc tttcgacatc
     2881 ttccacagaa cgaagtccat tgggttgcgt ttgtcgtcga ccacgtcaac gcgcgcgcct
     2941 gcctgcagct ggtcgagatc ctgacgcgac agcacgccat aagttggatc ggtcgggacg
     3001 tcgaacatca cgtcgccgtt gtccgccaca taagcgtgac ctttggcgat cagttgttca
     3061 gtgagttcaa taatttctgc gatatggtgc gtcgcgcgcg gctccatatc cgggcgcaga
     3121 atgttcaacg catcaaaatc tttgtgcatt tcggcgatca tgcgatccac cagcgccaca
     3181 aagctttcgc cattttcatt ggcgcgtttg atgattttgt cgtcgatatc ggtaatgttg
     3241 cgcacatact tcagcttata gccgaggaaa cgcagatagc gcgcaaccac gtcaaaagca
     3301 acaaaggtac gcccgtgacc gatatgacag agatcgtaaa cggtgattcc acacacgtac
     3361 atgccgactt ccccggcgtg aataggctta aattcctctt tttggcgtgt cagagtattg
     3421 aagattttta gcatcgaaga ttccgtttag acatgtgtgg gtaattgagt tgcgtataat
     3481 acccatattt cccgcgcgaa tcagcataca ttgcgtgatg atccgatcgt gcggttatgc
     3541 tataacacca ccctatatat gacccgaact gggttgaagc accaatcaaa cggaacagga
     3601 tgcaaaaatg gttactttcc acaccaatca cggcgatatt gtcatcaaaa cttttgacga
     3661 taaagcacct gaaacagtta aaaacttcct ggactactgc cgcgaaggtt tttacaacaa
     3721 caccattttc caccgtgtta tcaacggctt tatgattcag ggcggcggtt ttgaaccggg
     3781 catgaaacaa aaagccacca aagaaccgat caaaaacgaa gccaacaacg gcctgaaaaa
     3841 tacccgtggt acgctggcaa tggcacgtac tcaggctccg cactctgcaa ctgcacagtt
     3901 cttcatcaac gtggttgata acgacttcct gaacttctct ggcgaaagcc tgcaaggttg
     3961 gggctactgc gtgtttgctg aagtggttga cggcatggac gtggtagaca aaatcaaagg
     4021 tgttgcaacc ggtcgtagcg gtatgcacca ggacgtgcca aaagaagacg ttatcattga
     4081 aagcgtgacc gttagcgagt aatcgtggcg acactcttta ttgcagatct tcatctctgc
     4141 gtggaagaac cggcgatcac cgccggtttt ctgcgttttt tagcggggga agcccgcaag
     4201 gccgacgcgc tgtatattct tggcgatctg tttgaagcat ggattggcga cgacgatccc
     4261 aacccactcc atcgccagat ggcggcagcg atcaaagcgg tgtccgattc cggcgttccc
     4321 tgttatttca ttcatggcaa ccgtgatttt ctgctcggca aacgctttgc ccgtgaaagc
     4381 ggcatgacat tattgccgga agaaaaggtg ctcgaacttt atggtcgccg ggtgttgatt
     4441 atgcatggcg acacgctgtg caccgatgac gcgggttatc aggcttttcg cgccaaagtc
     4501 cacaaaccct ggctgcaaat gctattcctc gctctgccgt tgtttgtgcg caaacgcatt
     4561 gccgcgcgaa tgcgcgcgaa cagtaaagaa gccaatagca gtaaatcgct ggcgatcatg
     4621 gacgttaacc aaaacgcggt agtcagtgcg atggaaaaac atcaggtgca atggctgatc
     4681 cacgggcata cccatcgccc ggcggtgcat gaacttatcg ccaatcagca acctgctttt
     4741 cgcgtggtac tgggtgcctg gcatacggaa ggttcgatgg tgaaagtcac ggcggatgac
     4801 gttgagctaa ttcattttcc gttttaaaaa acccgcaact ttgctgattt cacagccacg
     4861 caaccgtttt ccttgctctc tttccgtgct attctctgtg ccctctaaag ccgagagttg
     4921 tgcaccacag gagttttaag acgcatgtct tcccgcaata atccggcgcg tgtcgccatc
     4981 gtgatggggt ccaaaagcga ctgggctacc atgcagttcg ccgccgaaat cttcgaaatc
     5041 ctgaatgtcc cgcaccacgt tgaagtggtt tctgctcacc gcacccccga taaactgttc
     5101 agcttcgccg aaagcgccga agagaacggt tatcaggtga ttattgcggg cgcaggcggc
     5161 gcggcgcacc tgccaggtat gattgccgcc aaaacgctgg tgccggtgct gggcgtgcca
     5221 gtacagagcg ccgcactgag cggtgtcgat agcctctatt ctatcgtaca aatgccgcgc
     5281 ggcattccgg tgggtacgct ggcgattggt aaagctggcg cggcaaacgc ggcgttactg
     5341 gcagcacaaa ttcttgcgac tcatgataaa gaactgcacc agcgtctgaa tgactggcgc
     5401 aatgcccaga ccgacgaagt actggaaaac ccggacccgc gaggtgcggc atgaaacagg
     5461 tttgcgtcct cggtaacggg cagttaggcc gtatgctgcg tcaggcaggc gaaccgttag
     5521 gcattgctgt ctggccagtc gggctggacg ctgaaccggc ggcggtgcct tttcaacaaa
     5581 gcgtgattac cgctgagata gaacgctggc cggaaaccgc attaacccgc gagctggcgc
     5641 gccatccggc ctttgtgaac cgcgatgtgt tcccgattat tgctgaccgt ctgactcaga
     5701 agcagctttt cgataagctc cacctgccga ctgcaccgtg gcagttactt gccgaacgca
     5761 gcgagtggcc tgcggtgttt gatcgtttag gtgagctggc gattgttaag cgtcgcactg
     5821 gtggctatga cggtcgcggt caatggcgtt tacgcgccga tgaaaccgag cagttaccgg
     5881 ctgaatgcta cggcgaatgt attgtcgagc agggcataaa cttctctggt gaagtgtcgc
     5941 tggttggcgc gcgcggcttt gatggcagta ccgtgtttta tccgctgacg cataacctgc
     6001 atcaggacgg tattttgcgc accagcgtcg cttttccgca ggccaacgca cagcagcagg
     6061 cgcaagccga agagatgctg tcggcgatta tgcaggagct gggctatgtg ggcgtgatgg
     6121 cgatggagtg ttttgtcacc ccgcaaggtc tgctgatcaa cgaactggct ccgcgtgtgc
     6181 ataacagcgg tcactggaca caaaacggtg ccagcatcag ccagtttgag ctgcatctgc
     6241 gggcgattac cgatctgccg ttaccgcaac cagtagtgaa taatccgtcg gtgatgatca
     6301 atctgattgg tagcgatgcg aattatgact ggctgaaatt gccgctggtg catctgcact
     6361 ggtacgacaa agaagtccgt ccggggcgta aagtggggca tctgaatttg accgacagcg
     6421 acacatcgcg tctgactgcg acgctggaag ccttaatccc gctgctgccg ccggaatatg
     6481 ccagcggcgt gatttgggcg cagagtaagt tcggttaact ggtgctctat tcttgccgga
     6541 tgcggcgtaa acgccttatc cggcctaccg atccggtacc cattgtaggc ctgataagat
     6601 gcgtcaagca tcgcatcagg cattgtgcac caattgccgg atgcggcacc ggttgtaggc
     6661 ctgataagac gcgtcaagcg tcgcatcagg cacaaatgtc taatgcctac gactacagcg
     6721 aaatacaggt ccccgcttcg cccgccagcg tctcttcaat tcgcgataac gccccaatcc
     6781 acgcgggttt accacggctt ctgacataac cactcaccgc cgttaccttc ggccccatcg
     6841 aaccatcggc tttggcaaat ggcgctaact catccggtgt ggcatggcga atggcgcgtt
     6901 gctgcggcgt tccccagttt tcatataccg catcagcatc agtgaggatc accagcccat
     6961 cggcgttaat ctgctcagcg agcaacgcag cagcgagatc tttatcaatc accgcttcac
     7021 tccctgcccc atcttccgtc acaggcacac cgccgccgcc actgcaaatc accacatgcc
     7081 cctctttgag caacaactcg atggcttcgc tgtcgagaat tttacgcggt tgcggagacg
     7141 ccaccacccg gcgcaaatat ttaccatcac gtttcatctg ccagccgtaa gccgcttcca
     7201 gtgcctcttg ttcttctggc tgataaaccg gaccaataaa tttctctggc tgcaaaaacg
     7261 ccggatcatc aggcgaaacc tcaatgcgcg tcagcaccgt cgtcacgggc ggcatctgcg
     7321 gctgtgcgct caaactctgc gccagcatat agccaatcat cccctgactt tctgccacca
     7381 gcacatccag cggatacggt tctacctctt tccacgccag attctgcaat gccagcagcc
     7441 ccacctgcgg cccgttgccg tgaacaatcg ccagccgata agaacgggcc aggcgcgcca
     7501 gcgcgggtac agcactggcg atattgcgat attgattttc tgccgtcagc gcctcaccgc
     7561 gctggagtaa ggcgtttccc ccaagagcta caaccagtgt tttcatggtt ttccttgtaa
     7621 taattgttga ccaagccaga accccagcag tgtatctgcc cctgacgtat gccccagcgc
     7681 cagcagcgaa tcaatcgcaa cagcggtacg tttcgggcaa ctcagagcat gaacaaagtg
     7741 caggagtggc gaggcgaaat atccttgcgc ggcataacgt aaataactga cgctcaccgc
     7801 tgtggtaacg agttgcagat tgtcggaaca ggcaaaaaac tggcgaccgg agcgcgcatc
     7861 taaagcgcca taataccagg ccgccagcag cattccgctc agcgtgtcat catgactcgg
     7921 cgttaatccg gggcctttac ccagccagtg ccgccagtcg gtcttaacgc cattgagcgc
     7981 ggcctgaaaa cagtgacgaa actggcgtaa ctcagcaggc agcggatcgc ttgccgccaa
     8041 cgccagtggc ccgaaaagcc cggtttcctc cgcgcgttgc atccatgcag ctgcaagtgg
     8101 ttgaggatgc gcaggcggcg taatacgcag caaacaataa cgctgtggct gtttaaccgt
     8161 gaaacgcctg aggcgaatcc cttgagccac aacctgtggt cgttcattgc cgcataatcc
     8221 accgcataac gcatcgaatt gcgcacggcg aagcatccat cctccggggc cgaaaccact
     8281 accctgacga tgcagcgtta acagttcgcc gctttccgtc atcaggttaa tcgcccgtcg
     8341 ccacactccc gctaaccgcc aggactggcg ataattcggt gcactacggc tggcaagcag
     8401 aggatggatg atcgtcattg cgcgttcctc aaccaatccc catgctttca gccagtgctt
     8461 ccagcgcctg ttcaaaacac gccagcggtg cccgcacagt gcctgcgcca atctgcccga
     8521 tccccgcctc tttatgggcg ataccggtat tgatgagtgg cgtaatgccg gtttctacca
     8581 cgcgacgaat gtccagtccc aggcacgcgc cctgaaaatc ccagcctggg atctgcaact
     8641 gcatattgcg ctcaaggtaa atttccgcca tctcttcaga taccgctctg gccgcctcca
     8701 tgccacccgc accgacaaag cgcgttacgc caggcgctgc gatcattgcc gcacctccga
     8761 taccaaaggt ttcggtaatc gcgctatcgc ccatatccgg gttcgcctgc tcctgcgaga
     8821 agccggtgaa aaacagacct tgcggagtgt ttacaggcgc agtaaaccag cgttcgccca
     8881 gcccgcttac ccgaatcccg aacatattgc cgttgcgggt cattgccgtg acgatgctgc
     8941 ctgcgcggat catcgcgcca gcatccatcg ccgccttgca gtaagccatc gcgaggttga
     9001 ggaagaactg atcggtcacg ctgaggaaat ccatcacttc ggcgatgtgc tgtttatcat
     9061 gatcgaggcg agcaatttgt ggggccagcg cacgcattaa cagtgcagag gaagcaatat
     9121 tgcgttgatg gaactcatcg cccatcgtaa tgccctgcgc catcatcgcc gtgagatcga
     9181 taccgcgctc catgcgcccc agcgccgcgc ttaatactgg cattaacaca tcgcgcatcc
     9241 agcgatggcg agtcaggaca tcttcgccgt aagcgccaaa acgcatcact ttgccgatac
     9301 cttcgttgag gttgcagtac gcccggttgc cgtcggtcac gttctcaacc accagcatcg
     9361 gcatactggc agaagtaata ccgcccattg gaccgacggc attcacatgg tgacaaggaa
     9421 tgaagttcac ttccccctgc tccagtattg ccagcgcctg cgcttcatct ttcgcccagc
     9481 cttcgaacag acatgcgccc acgcacgccc ctttcatggg tccggtcatc tcctgccagc
     9541 gcattggcgg cccggcgtga agcagtgttt tgccctcgtt tagttcgctg ataagtgaag
     9601 aagccggttg cacatccagc cagtgtggac gagcgcgacg aatttgttcg ataaccgcag
     9661 cattggcttg cgccactgat gtaaacatgg gaacccctta ttgcaaacgt tctaataaac
     9721 gagccagttt tttattgccg ccggcgactg gcgaccattg gtaatgcaca accggtttgc
     9781 tggcgctttg tagctccagc gcaaagctgc gtaatccgat gttaatcacg gcgacgtttt
     9841 ccagtaatga cggtgtgtgt tgctgagtgg caggcgaaag cggacgaatc agtgccgccg
     9901 ccagcaaggt ggcttccggc agcgaactca ctaccgcgat ccctgcatct tccagcgtgg
     9961 cgatttgctg cgagcggcat tgcgggtcac gttcagtgcc tgtcaccgtg gcaatggcat
    10021 acagtggttg attgtctgaa cgcgcggcac atgctttttg ccaggcgctt accagcgagg
    10081 cggcaggatc ggcggtcgca ccgaagccaa tcacgacatc aagcagcaat acgcgcactt
    10141 gcggtttagc gccgagatcg gcaattaact gattgcgtaa ggctgggtcg atcatcggat
    10201 ggggacgccc gacggtgtag aaatcatcgc cgaggtcaat aatctggtga ccatcggcgt
    10261 cgagcatcat gccgtgatga tgggtatcgt cggcttccac gccaaggtgt ccagcaagta
    10321 atcccgccgc ttcggcagcc agggtaccgc cggtatacaa accgcaaata aatccgctgc
    10381 tggcaggcgt tatcgcgtta cgtcgcgccg taacgcgtga aagcaggcaa gccaggcgtg
    10441 cggcctcatc cagcgaggag gcaaaccaga cattctcgtc gcgggccacc gccggggtat
    10501 aacctaaaaa cagcgccacc gtcggtttgc cggttgcttt catggcatta acaattttca
    10561 gacgcacagc ttcggcaggc ggttttgaaa caaatgccag cacttcgctt ttctcgtctg
    10621 cactgagcat ttccagcgcc gtcagcgcac tgatgccgcc cacttcacgg ctgaggtcgc
    10681 gcccgccaag gccaatcgcg tgagtaattc cctcccctgc cagcgcaatc tgcgaacaca
    10741 gttcctgaat cccggtaccg gaagcgccaa tgacgccaat attgccttcc ggcatcacgt
    10801 tagcaaaagc cagcggcgtg ccggcaatca tcgacgtacc gcagtccggc cccatcacca
    10861 gcaagccttt ttcccgcgcg cggcttttaa gttggatttc atcttccagc gtgacgttat
    10921 cggagaacat catcacgttg aggttgcgat ccagcgcctg gttcgccagc tccgccgcat
    10981 actcgccagc cactgaaatc agcgccagac tggcgtcggg taatttctga caggcactgt
    11041 cccagcgacg cacctgcgtc aacgcctggc tgctgcctga cccctgcgcc agttgtttta
    11101 gcgcctcttc aagctgctgc ataatcgcct gcgcgatccc cgcatccgcc gcttcgctac
    11161 gaattgccac gcaaatatcg ttcggcgtgg cgttattaaa atcgtcatgc cagaaacctg
    11221 tggtatctaa taacgcttta ttggcgggcg tacccatcat tacggaaaca tcatcaacat
    11281 tttctgattc gctgagtttt cgtgaaataa tcattaaact gaccgaatcc tgaaaacacc
    11341 cttttttaat aaaggcgtgg atcataacaa ctccttaaaa attgcaccca tggcaattgc
    11401 acgagcagtg ttaatgtggc gattacggta tcgatgacaa cgagtaaata aggtgatgaa
    11461 tatcacacag gaattattaa caaaagaatt caaataaccg ccaggctatt actcattatt
    11521 ttttaataag cgtggttgtt ttaaaaatca ggttaaaagt gagcggatta tcaaataaat
    11581 tctaactata ttttcttgcc tgtctggatc acataatcca gatattttcc ctgtatgtta
    11641 attgcagtca tgcttcacac cgtcgttaaa aaggaagaca gatgaaaatc agtcgggaaa
    11701 cactccacca gctaattgag aataaactct gccaggctgg gttaaaacgt gagcacgctg
    11761 caaccgtggc tgaagtattg gtttacgccg atgccagagg gatccactct catggcgcgg
    11821 tgcgcgtgga atactacgcg gaacgcattt caaaaggcgg caccaaccgc gaaccggagt
    11881 ttcgtcttga ggaaaccggg ccgtgctcgg caattttaca tgccgacaat gccgccggac
    11941 aggtcgcggc gaaaatgggt atggaacatg ccatcaaaac cgcccagcaa aatggcgttg
    12001 cggtggtcgg tatcagccgg atgggtcaca gcggcgcaat ctcttatttt gtgcagcagg
    12061 cagcccgcgc cggattcatt ggcatttcga tgtgccagtc cgatccaatg gtggtgccgt
    12121 ttggcggcgc ggaaatttac tacggtacta accccctggc ctttgccgcg ccgggagaag
    12181 gcgacgagat ccttaccttt gatatggcga ctaccgtaca ggcatgggga aaagtgctcg
    12241 acgcccgctc gcgtaatatg tctatcccgg atacctgggc ggtcgataaa aacggtgtac
    12301 caacaaccga tccgttcgcg gtacatgctc tgctccccgc cgccgggcca aaagggtatg
    12361 gcctgatgat gatgattgac gtcctctcag gcgtcttact cggcttaccg ttcgggcgac
    12421 aggttagttc gatgtatgac gatttacacg cagggcgtaa tttggggcaa ttacatatag
    12481 ttattaatcc gaactttttc tcctccagcg aattattccg tcaacatctt agccagacca
    12541 tgcgcgaatt aaatgccatt acccccgcgc ccggttttaa tcaggtttat tatcccggac
    12601 aggatcagga tattaaacaa cgcaaagccg ccgtcgaagg catcgaaatt gttgatgata
    12661 tttaccagta tttaatttcc gacgcgcttt ataacacgtc atacgaaacg aaaaatctct
    12721 ttgcgcaata attattgaga caggactttc ttatgattac acatttccgt caagctatag
    12781 aagaaacgct gccctggctt tcctcttttg gcgctgaccc agcgggtggg atgacccgtt
    12841 tactttattc gccggaatgg ctggaaaccc agcagcaatt taaaaaaaga atggcagcaa
    12901 gcgggctgga aacacgtttc gatgaagtgg ggaatttata cggtcgcctg aatggcaccg
    12961 aatatccaca ggaagtggtt ctgagcggtt cgcatatcga taccgtggtt aacggcggta
    13021 accttgacgg gcaattcggc gcgctggcgg cgtggctggc aattgactgg ctgaaaacgc
    13081 aatacggcgc gccgctacgt acggtcgaag tggtggcgat ggcagaagaa gaaggcagcc
    13141 gcttcccgta tgtcttctgg ggcagtaaaa atatttttgg gctggcgaat cctgacgacg
    13201 tgcggaatat ctgtgatgcc aaaggaaata gttttgtcga tgcgatgaag gcttgcggat
    13261 ttactcttcc gaacgcccca ctaactccgc gtcaggatat taaagccttt gttgaactgc
    13321 atattgaaca gggctgtgtg ctggaaagta atgggcaatc aattggcgtg gtgaatgcaa
    13381 ttgtcgggca gcgtcgttat acggtaacgc tgaacggcga atcaaaccat gcaggcacca
    13441 cgccgatggg ttatcgtcgt gatacagttt acgctttcag tcgcatttgc catcagtcgg
    13501 tcgaaaaagc gaaaaggatg ggcgatccgc tggttctgac ctttggcaaa gtagagccgc
    13561 gcccgaatac ggtaaatgtg gtgccgggta aaaccacgtt caccattgat tgtcgtcata
    13621 ccgacgctgc cgtgctgcgc gatttcaccc aacagttaga aaacgacatg cgggcgattt
    13681 gcgatgaaat ggacattggt attgatatcg atttatggat ggacgaagaa cccgtgccga
    13741 tgaataagga gctggtcgcc accctgacag aattgtgtga aagagaaaaa ctgaattacc
    13801 gggtgatgca cagtggtgcc gggcacgacg cgcaaatttt cgcgcctcgc gtaccaacct
    13861 gcatgatttt tatccccagc atcaacggga tcagccataa cccggcggaa cgcaccaata
    13921 ttaccgacct tgccgaaggg gtcaaaacgt tggcactcat gctttatcaa cttgcctggc
    13981 agaaataagg agtcataaat gggatattta aataacgtca ccggttaccg cgaagattta
    14041 ctggctaacc gtgcgattgt taaacacggt aatttcgcac tgttaacccc ggatggtctg
    14101 gtaaaaaata ttattccggg ctttgaaaat tgtgacgcga caatcctctc cacgccaaag
    14161 ctgggtgcct cttttgttga ttatctggtc acactgcatc aaaacggtgg caaccaacag
    14221 ggcttcggtg gcgaaggcat tgaaacgttc ctgtatgtga tctctggaaa tatcactgcc
    14281 aaagccgaag gcaaaacatt tgccttaagc gaaggtggct atctttattg cccgccaggc
    14341 tccttaatga cgtttgttaa cgcccaggcc gaagacagcc aaatcttttt atataagcgc
    14401 cgctatgttc cggtagaagg ctatgcaccg tggctggttt ctggcaatgc cagcgaactg
    14461 gaacgcattc attatgaagg catggacgat gttattctgc tggattttct gcccaaagag
    14521 ttaggttttg atatgaacat gcatatcctc tcttttgcac caggtgccag ccacggttat
    14581 atcgaaacac acgttcagga acacggtgcc tatattcttt ccggtcaggg ggtttataac
    14641 ctcgacaata actggatccc ggtgaaaaaa ggcgattaca tctttatggg cgcttattct
    14701 ttacaggctg gttatggtgt agggcgtggt gaagcgttca gctatattta ctcgaaagat
    14761 tgtaaccgcg acgtagagat ttaagtcata ccactcgcct gattattttt agctatgttg
    14821 gattttgcca cggtttatac cgtggctttt tttgtaacat tgcctgatgc gcttcgctta
    14881 tcaggcctac atgatctctg caatatatag aatttgcgcg attttcagga aggatatggt
    14941 actcatgccg catccggcat gagtactgca ctcttatgcg atataaatcg catccgcttt
    15001 aaaggtaagg gttagttttt aattccctga cctattttaa tggcgcaggc aatatttcgc
    15061 gcgctgttga agagattggt ttcaccgctg gcgagcactt cggctaaagg tgccagacga
    15121 ggcaaaatgc tgaataccgc gtcaatgccg tactggtgca ccacttccac gccatcaccc
    15181 aatacgccag caatcccaat caccggtaca ttaaactgct tcgccaccga cgccacaccc
    15241 agcggcgctt taccgcctgc cgtttgcgag tcgatgcgcc cttccccggt aatcaccagt
    15301 gctgcgccct gcactgcctg cgcaagattg accgcattca acacaatttc aatgcccggt
    15361 ttaatatccg cattgagaaa taccgccgcc gcaataccca taccgcccgc agcgccgccg
    15421 cccgccatct ggcagacatt aatttcagtt tgctgttgta aaacacgggc gtaattttgc
    15481 agcccctgtt caagttcttc gaccatctcc ggcgttgccc ctttttgcgg gccaaacacc
    15541 gccgccgcgc agcgtgcccc taccagcggg ttatcaacgt cacatgctac ttcaatatgg
    15601 caattcgcca gacgcggatc gcattcatcc atctcaatgc ttgccacgcg cgctaaatta
    15661 ccaccgtttg ccgccagcgc ctgaccgtcg gcatcaagga aacgcacacc gagcgcctgc
    15721 gccatgccca taccgccgtc gaccgtcgca ctgccgccaa tgccgagaat aatatggcga
    15781 atgtcgttat ccagcgcatg acgaattaac tcccccgtac caaaactgga ggccagcaac
    15841 ggattacgct tttcaggcgc gaccagcatc aggccacttg ctgccgccat ctcaatcacc
    15901 gccgttttcc cgtcgccggt aaggccataa aaagcattca ctttttcgcc catcggcccg
    15961 cagacttcaa gcgtcacgat gttgccgccc gtcgcggcga ccatcgcatc caccgtccct
    16021 tcgccgccat ccgctatcgg caaacagata tagttcgcat cgggaaagag ggtcgaaaac
    16081 ccggctttaa ttgcctgaca acatttttct gcacttaagc tctctttaaa agagtctggc
    16141 gcaatgacaa tcttcattat caatcctttt tcaacaaatt attcgatgcg ttcccacgga
    16201 ataaggttat ccataagaac agccagtaaa atcccgacca ataagccgtt actgagcaga
    16261 ggacgaagcg ttaatggaag gtcttgcaga tacacaggcg gtaatgccat taaaaatatg
    16321 ccgacaaata acggcaatgc gagtcgataa atattgcgag cggtaaacgt tatttgctgg
    16381 ctaaacacca gcgcggaaaa gagtaaaggc agataagaaa ccagcatgac cgcactactc
    16441 acgggtaaag ggatactgca aaacagtcgc gtgagtgcag gaaccagcgc caccagcagg
    16501 caaataacgc tgccataaat aaacgaacgc cgcgtgtaat cgccagtctg ggttaataaa
    16561 ccaatggatg aaacaaacgg tgaaaatgga attaccgcca gcggtacggt tatcagcgtc
    16621 ataaatccgg tcgccacaaa gctacgacga taacgcgtat tccctgcgcc ctgctgcgga
    16681 taaaaaacat ccgtgccccg aatcgcaccg taggtattgc tgatatttac cagacctgta
    16741 atcaccgccg tcagaataat tcccggcgac aaagcaccgc cactgccgag cgggaaccac
    16801 tgccagtgca actcaccgga gagcgagtgc gaagaaggaa agcaaaagta ccacaacaac
    16861 cagccggtta tggtgccgac cagcaggcca taacgggcaa aacgttgcgg caggaagata
    16921 atcatcgcca gtaccaggca catcaccgcc accgagagcg cgaacggcgg taactgaatt
    16981 ttaaaattcg ggtcggctat gccaaacggc agcccgagca tacctttgaa aaagatagtg
    17041 gtcagctgcg cgcccagcat caacataaac aagaccatca ccgacggcgt aaataaccgt
    17101 gccaggcgat ggcctaatcc gctaaaacca atcaacatcg tcagcacgcc ggagagtgca
    17161 atccccactg ccaggctggt ggcgatatcg ttgatcggtg tcccgcgcga tgcttcacca
    17221 agggtgatag taaggatggt tccccaccac aggccacctg gcccttccat aatagcgcga
    17281 cgatgaccgc aaaacgcctg agcgaagcag gccagtgcgg tagcaagaaa agcatattgc
    17341 gtgagcgtaa gcaggctact ttgcggcaac tgaaaagcag aaagtagcgt aggaggaacc
    17401 acaaccgtgt tgcaaaaaat aaagaaaaac cactgaaatc ctgataacag gctttcgcgg
    17461 ctgactgcaa aattgaacat aaacacacct taaccggaga atgcccgccg caaggacggg
    17521 cattgcaggg gccagattac tgctgatgtt taaggataaa ttgacctttc ggcgcaacag
    17581 ggaagccctg ttcaatgtcg taaatcacat caccacgtaa gatggttttc gtgatacgcg
    17641 cgccaatggt acggccaaca tacgggctga ctttgtggcg atattccaga tcgtcattgg
    17701 taagaacata gctgctattc ggctgaatga agacgaagtc ggcatctttt cctggggcga
    17761 tacggccttt ttgctgcaga ccgaaaatat ctgctgcgtt agtcgccatt aatttgccga
    17821 acattggcag agacataccg cgtttctgta ccgcttcatc gaacatcacg tccatgcagc
    17881 tttgcagacc ggcgataccg ccccatgctt tcatgatgtt accggctttc atttccggcg
    17941 ggcatggaga gtggtcggaa accaggcagt cgatttcacc gttaaacagt ttttcccaca
    18001 tgcctttctg gttttccaga tcgcggatcg gcggtgaaca cttcgccaga gtaccgattt
    18061 cttcgaactg atcggtatcc agtacaaagt aatgcgggca ggattcacaa gtaacgtcct
    18121 gaccttcctg acgtgcacga gtcacttcct caacaccttc cgggctgctg acgtggcaaa
    18181 cgtgcagacg gcaaccagca actttcgcca gatacagtac gcggcgaatt gcttccactt
    18241 cggtaaatac cggacgcgaa gccacatagt catgagcggt tacgcgacct tcacgcttcg
    18301 cttcttcgcc cagttcgtca caaatcagcg cgttttcgca gtgcaccagc accggctgac
    18361 ccagttcgcc cagcttctgc gcacctttga agaactgcca gtcgtttaca tcacggaagt
    18421 cgttgtcgat accgcgatcg ccacaggtcg caacgaagca tttgaagccg acaacgccca
    18481 cttcatccag ctcatgcaga cggtcgatgt tgtaagacac caggccaccg agttgtgccg
    18541 catcaatagt cagcttgcct ttagcggcat cgaacttcag ttcaattgaa gcgcggtcaa
    18601 ccgttgcagg cagctggttg agcggcattt cgatcatggt ggtgatacca ccttttgccg
    18661 ctgcgcgagt accggtttca taaccttccc agtggctacg acccggttca gaaatatggg
    18721 tgtgcgcatc aaccatgccc ggcgaaacca ccagaccaga cgcatccata acttcttttg
    18781 catcgcccag atcctgaccg atagcagcaa tttttccgcc tttaacggcg atatctacaa
    18841 cgcgagcttc gttttctaaa ataacggtgc cgtttttaat gattaaatca aaagacataa
    18901 caaactcctt gtaaaataca gattggtttt taactcaatg ttcaatatcg ggattaatta
    18961 acctatggtt ttttgctctc ctgttttttc tgctgttgta cgtttcttta ataaggcgta
    19021 ggccgcaaag gcgacgatga cgccgacaaa ccatgaaaca cgcgataacg gttccataaa
    19081 gtgaataaac ttaccgccaa gagataaaat aacggccacc agagttactg aaaacgcagt
    19141 gaggttaaaa ccgttatcgt aatatttata atcgccaggt gcggtataca gttcatcaag
    19201 attaatttgt ccgcgcatca ccacaaaata atgcgccatc atgacaccaa ttaccggacc
    19261 aagcattccg ccgataatat cgaggaaaag ataaatgctg tcctgatttt ccattaattt
    19321 ccacgggcag atcagcaagc tgataatact ggcaatcagt acgccgtttt tataggtcag
    19381 ttttgtcggt gcaatggcgg caatctgata accggctgga ataatattac cggtcgcgtt
    19441 agtggagata gttgtcatca gaataaccag taccgcaaag aacgaggcga acaggctgtc
    19501 ccaacgctga acaatatcca gcacgttcca ggtatcagcg ccgtagtgaa tactggctcc
    19561 ggcaataata cataccccgg cgaccgcaaa cagaatatag gccacaacta aacccagcgt
    19621 ttgccccagc gcctgctcac gaaacgagtg ggcgttttgc gtaaagtcgg atgcgctcac
    19681 cgccggtgcc gcccagaccg caactaccgc gttaatcacc accaggaaca ggaagccacc
    19741 gttttctgct ttctgaatac cgctcggaat gtagtcaaag attggaccga tcccgaccag
    19801 tgaaatcgcc caaatcgcca taccgccgaa aacgatatag atgcacgggt taagaatggc
    19861 agtgaattta tttaaaactt tgccaccgcc aaaacctata ccaacgttga ccagccagaa
    19921 gattaagaaa gtaattaagc ccggtagaga aaggcctaac agagtgaaat caccaccgag
    19981 agttaaaaat cccggccaga ttttgccaat cagaatcaag caggccagtg accccgcgta
    20041 acattgcaaa ccaaaccaca tgatggcggc aattccgccc cttaataatc cgggaaacag
    20101 tgcaccacgt acaccgtaag aagcacgcag gatcatggca aaaggcacac cgtatttact
    20161 gcccgcagca ccgtttaata ccattaccgc ggcaatgaaa aaggcgctga ggataattgc
    20221 cagcataata ctaaaggtag acaagccgag aataaaaaag ccgccgacca tcacataatt
    20281 gggaacgtta tgaaccgaac ccatccataa ggtaaaatag ttaaatgttt tccaggtccg
    20341 ctggctttgc gttttcggca atagatcttc gctatagccg cgttgctgga atagttttct
    20401 ctgatgttcc ataaatccct cttaatttca cgtatcgaat aacgttgttt taatctagct
    20461 atgaggaaca
//
LOCUS       DAPHKZ010000077        20468 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.077, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000077 DAPHKZ010000000
VERSION     DAPHKZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20468
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.077"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(205..951)
                     /gene="cutC"
                     /locus_tag="RH288_002957"
     CDS             complement(205..951)
                     /gene="cutC"
                     /locus_tag="RH288_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025309.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDV4031996.1"
                     /translation="MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLK
                     SVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVD
                     MPRMEKIMAAAGPLAVTFHRAFDMCANPLYTLNNLAELGIARVLTSGQKSDALQGLSK
                     IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSS
                     DEHADEYSRYIVDGAAVAEMKGIIERHQAK"
     gene            complement(965..1531)
                     /locus_tag="RH288_002958"
     CDS             complement(965..1531)
                     /locus_tag="RH288_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416389.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDV4031997.1"
                     /translation="MANWQSIDELQDIASDLPRFIHALDELSRRLGLNITPLTADHIS
                     LRCHQNATAERWRRGFEQCGELLSENMINGRPICLFKLHEPVQVAHWQFSIVELPWPG
                     EKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNP
                     TLAVTDGKTTIKFHPWSIEEIVASEQSA"
     gene            1747..3480
                     /gene="argS"
                     /locus_tag="RH288_002959"
     CDS             1747..3480
                     /gene="argS"
                     /locus_tag="RH288_002959"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDV4031998.1"
                     /translation="MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALAS
                     DRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQ
                     SGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            3657..4145
                     /locus_tag="RH288_002960"
     CDS             3657..4145
                     /locus_tag="RH288_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416391.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HDV4031999.1"
                     /translation="MFKFLVLTLGIISCQAYAEDTVIVNDHDISAIKDCWQKNSDDDT
                     DVNVIKSCLRQEYNLVDAQLNKAYGEAYRYIEQVPRTGVKKPDTEQLNLLKKSQRAWL
                     DFRDKECELILSNEDVQDLSDPYSESEWLSCMIIQTNTRTRQLQLYRNSEDFYPSPLT
                     RG"
     gene            complement(4265..4657)
                     /gene="flhe"
                     /locus_tag="RH288_002961"
     CDS             complement(4265..4657)
                     /gene="flhe"
                     /locus_tag="RH288_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HDV4032000.1"
                     /translation="MRTLLAILLFPLLVQAAGEGMWQASSVGITLNHRGESMSSAPLS
                     TRQPASGLMTLVAWRYQLIGPTPSGLRVRLCSQSRCVELEGQSGTTVAFSGIAAAEPL
                     RFIWEVPGGGRLIPPLKVQRNEVIVNYR"
     gene            complement(4657..6735)
                     /gene="flhA"
                     /locus_tag="RH288_002962"
     CDS             complement(4657..6735)
                     /gene="flhA"
                     /locus_tag="RH288_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDV4032001.1"
                     /translation="MSNLAAMLRLPANLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NIVGGLLVGVLQHGMSMGHAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVNQLFSNPSVMLLSAAVLGLLGLVPGMPNLVFLLFTAGLLGLAWWIRGREQKA
                     PAEPKPVKMAENNTVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQEMGFLPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLP
                     GEATVDPAFGLNAIWIESALKEQAQIQGYTVVEASTVVATHLNHLISQHAAELFGRQE
                     AQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILETLAEHAP
                     IQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(6728..7876)
                     /gene="flhB"
                     /locus_tag="RH288_002963"
     CDS             complement(6728..7876)
                     /gene="flhB"
                     /locus_tag="RH288_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HDV4032002.1"
                     /translation="MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSV
                     IWFGGVSLARRLSGMLSAGLHFDHSIINDPNLILGQIILLIREAMLALLPLISGVVLV
                     ALISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKTILVGSVTG
                     FFLWHHWPQMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKK
                     LRMSRQDIRDEFKQSEGDPHVKGRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVAL
                     QYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARALYRHAEIGQQIPGQ
                     LYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE"
     gene            complement(8078..8722)
                     /gene="cheZ"
                     /locus_tag="RH288_002964"
     CDS             complement(8078..8722)
                     /gene="cheZ"
                     /locus_tag="RH288_002964"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HDV4032003.1"
                     /translation="MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPI
                     DLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF"
     gene            complement(8733..9122)
                     /gene="cheY"
                     /locus_tag="RH288_002965"
     CDS             complement(8733..9122)
                     /gene="cheY"
                     /locus_tag="RH288_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002210873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HDV4032004.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(9137..10186)
                     /gene="cheB"
                     /locus_tag="RH288_002966"
     CDS             complement(9137..10186)
                     /gene="cheB"
                     /locus_tag="RH288_002966"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HDV4032005.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYNEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGE
                     RVLPGHAYIAPGDRHMELSRSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAV
                     GVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(10189..11049)
                     /gene="cheR"
                     /locus_tag="RH288_002967"
     CDS             complement(10189..11049)
                     /gene="cheR"
                     /locus_tag="RH288_002967"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDV4032006.1"
                     /translation="MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHH
                     FPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
                     EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFAPLNLLAKQY
                     TVPGPFDAIFCRNVMIYFDQTTQQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLR
                     GQTVYALSKD"
     gene            complement(11068..12669)
                     /gene="tap"
                     /locus_tag="RH288_002968"
     CDS             complement(11068..12669)
                     /gene="tap"
                     /locus_tag="RH288_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein IV"
                     /protein_id="HDV4032007.1"
                     /translation="MFNRIRISTTLFLILILCGILQIGSNGMSFWAFRDDLQRLNQVE
                     QSNQQRAALAQTRAVMLQASTALNKAGTLTALSYPADDIKTLMTTARASLTQSTTLFK
                     SFMAMTAGNEHVRGLQKETEKSFARWHNDLEHQATWLESNQLSDFLTAPVQGSQNAFD
                     VNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPL
                     AIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIG
                     IAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQ
                     AGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGF
                     AVVASEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMIDIVSSVTRVND
                     IMGEIASASEEQQRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRV
                     AVFTLEEHEVARHESVQLQIAPVVS"
     gene            complement(12715..14376)
                     /gene="tar"
                     /locus_tag="RH288_002969"
     CDS             complement(12715..14376)
                     /gene="tar"
                     /locus_tag="RH288_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HDV4032008.1"
                     /translation="MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSN
                     QLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAAT
                     HYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNA
                     MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLT
                     PLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIY
                     AGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDT
                     AQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF"
     gene            complement(14521..15024)
                     /gene="cheW"
                     /locus_tag="RH288_002970"
     CDS             complement(14521..15024)
                     /gene="cheW"
                     /locus_tag="RH288_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDV4032009.1"
                     /translation="MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVV
                     DGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
                     SAASEVA"
     gene            complement(15045..17009)
                     /gene="cheA"
                     /locus_tag="RH288_002971"
     CDS             complement(15045..17009)
                     /gene="cheA"
                     /locus_tag="RH288_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDV4032010.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIF
                     RAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPR
                     RIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEA
                     DQITFETVEVSPKISTPPVLKLAAEQAPTGRVEREKTTRSNESTSIRVAVEKVDQLIN
                     LVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFS
                     RYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKR
                     LAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEV
                     AMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGTGTTIRILLPLT
                     LAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWK
                     VFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
                     ILGDGSVALIVDVSALQAINREQRMANTAA"
     gene            complement(17014..17940)
                     /gene="motB"
                     /locus_tag="RH288_002972"
     CDS             complement(17014..17940)
                     /gene="motB"
                     /locus_tag="RH288_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HDV4032011.1"
                     /translation="MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVM
                     WLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPN
                     IEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
                     FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRA
                     NASRRELMVGGLDSGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHE
                     NAESQNEPVSALEKPEVAPQVSVPTMPSAEPR"
     gene            complement(17937..18824)
                     /gene="motA"
                     /locus_tag="RH288_002973"
     CDS             complement(17937..18824)
                     /gene="motA"
                     /locus_tag="RH288_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HDV4032012.1"
                     /translation="MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGS
                     FIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLALLYRLMAKSRQMGMFSLERDIE
                     NPRESEIFASYPRILADSVMLDFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
                     PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLATVLRQKSAETSKMMQCVKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVKNPQQQTTTEEA"
     gene            complement(18951..19529)
                     /gene="flhC"
                     /locus_tag="RH288_002974"
     CDS             complement(18951..19529)
                     /gene="flhC"
                     /locus_tag="RH288_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HDV4032013.1"
                     /translation="MSEKSIVQEARDIQLAMELITLGARLQMLESETHLSRGRLIKLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLY
                     LEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV"
     gene            complement(19532..19882)
                     /gene="flhD"
                     /locus_tag="RH288_002975"
     CDS             complement(19532..19882)
                     /gene="flhD"
                     /locus_tag="RH288_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416406.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HDV4032014.1"
                     /translation="MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMAT
                     TLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLN
                     DVNQPEEALRKKRA"
BASE COUNT         4932 a         5611 c         4968 g         4957 t
ORIGIN      
        1 agttttagta atttaaatcc cataattaat gtgaatatat acaatatttt tagcacaacg
       61 ctatgcgcac tgtcacccgc tcaacagatc acggttatcg ttcgtttttt atactgttca
      121 gggataaaaa aaggcccctg ttgaaattgc aggggcctgg tacgagcaag catcatattg
      181 ggcgacatga tgcaacggta aaaatcattt ggcctgatgg cgttcaatga ttcctttcat
      241 ttcagcaacc gccgccccgt ctacgatata acgcgaatac tcgtccgcgt gttcatctga
      301 tgacatggac aatccttgat tacgataacg catcggtgag gcttgccacg ctcccgcgga
      361 gctatggact tccagcactc cggcatcgag gaagtggtgc aggttttctg cacggactcc
      421 tgctccggcc ataatgattg gagcatcacg atgggcaata agttccataa tttttgataa
      481 accttgcagt gcgtctgatt tttgccctga tgtcagtacc cgggcaatgc ccaattccgc
      541 aagattattg agtgtatata aagggttagc gcacatatcg aaggcgcgat gaaaagtcac
      601 tgccagcgga ccggcagcag ccattatttt ttccattcgt ggcatatcga cattcccgtc
      661 aacatcgaga acgcccgtca ccagtccagg aaaacctaat tcgcggaccg tgcgcacatc
      721 ctcaagaatg gcggcaaact caccgtcgct gtagcaaaaa tcaccaccgc gtgggcgaat
      781 tatcggatgc acagggatcg tcacccgctg gcgcacggat ttcagtacac ccaacgacgg
      841 cgttaagccc ccctcttttg gggctgcgca taattcaact ctgtctgcgc cgttttgctg
      901 cgccgttagt gcacattcca tgctgtaaca gcaaatttcc agtaatgcca tttttactcc
      961 ttaattacgc cgactgctcg ctggcaacga tctcttcaat ggaccacgga tgaaacttaa
     1021 tagttgtttt gccatcggtg accgccagcg tcggattcgg taatcgctca tgctcacctt
     1081 ttggcgaact ggttttcact gagatccccg gtaggctgag tccttcatca gaaagcaatg
     1141 ccagcgcacg ggcattcagc gtttctggat cacccggcag aacgatttca atatgttccc
     1201 aaccttcgtg tgggtaacgt ttttccccgg gccacggtag ctccacaata gaaaactgcc
     1261 agtgcgcaac ctgtaccggt tcatgcaatt taaacagaca aatcggtctg ccattgatca
     1321 tattttctga caaaagctcg ccacactgtt caaacccgcg acgccagcgt tcagcagtgg
     1381 cgttttgatg gcaacgcaaa gaaatgtgat cggcagtcag cggagtgata ttcaacccca
     1441 gacggcggga aagttcatct aatgcgtgga taaatcgcgg taaatccgat gcaatatcct
     1501 gcagctcgtc gatagattgc cagttcgcca taatcactct tcgtctttca gtaaaagcgt
     1561 taatttaccc tgttgccctg tgccaaccaa ccgctgattt cacgccgctt ctgatgcaat
     1621 agtgaaaacg gcaatacgcc acgcgcacgt tgctgacgaa aacagccatt tgcagtatac
     1681 tcccgcccta atttctttaa ctggtgcggg caatttttgc tcgcttcatc aatgtaaggt
     1741 attccggtga atattcaggc tcttctctca gaaaaagtcc gtcaggccat gattgcggca
     1801 ggcgcgcctg cggattgcga accgcaggtt cgtcagtcag caaaagttca gttcggcgac
     1861 tatcaggcta acggcatgat ggcagttgct aaaaaactgg gtatggcacc gcgacaatta
     1921 gcagagcagg tgctgactca tctggatctt aacggtatcg ccagcaaagt tgagatcgcc
     1981 ggtccaggct ttatcaacat tttccttgat ccggcattcc tggctgaaca tgttcagcag
     2041 gcgctggcgt ccgatcgtct cggtgttgct acgccagaaa aacagaccat tgtggttgac
     2101 tactctgcgc caaacgtggc gaaagagatg catgtcggtc acctgcgctc taccattatt
     2161 ggtgacgcag cagtgcgtac tctggagttc ctcggtcaca aagtgattcg cgcaaaccac
     2221 gtcggcgact ggggcactca gttcggtatg ctgattgcat ggctggaaaa gcagcagcag
     2281 gaaaacgccg gtgaaatgga gctggctgac cttgaaggtt tctaccgcga tgcgaaaaag
     2341 cattacgatg aagatgaaga gttcgccgag cgcgcacgta actacgtggt aaaactgcaa
     2401 agcggtgacg aatatttccg cgagatgtgg cgcaaactgg tcgacatcac catgacgcag
     2461 aaccagatca cctacgatcg tctcaacgtg acgctgaccc gtgatgacgt gatgggcgaa
     2521 agcctctaca acccgatgct gccaggaatt gtggcggatc tcaaagccaa aggtctggca
     2581 gtagaaagcg aaggggcgac cgtcgtattc cttgatgagt ttaaaaacaa ggaaggcgaa
     2641 ccgatgggcg tgatcattca gaagaaagat ggcggctatc tctacaccac cactgatatc
     2701 gcctgtgcga aatatcgtta tgaaacactg catgccgatc gcgtgctgta ttacatcgac
     2761 tcccgtcagc atcaacacct gatgcaggca tgggcgatcg tccgtaaagc aggctatgta
     2821 ccggaatccg taccgctgga acaccacatg ttcggcatga tgctgggtaa agacggcaaa
     2881 ccgttcaaaa cccgcgcggg tggtacagtg aaactggccg atctgctgga tgaagccctg
     2941 gaacgtgcac gccgtctggt ggcagaaaag aacccggata tgccagccga cgagctggaa
     3001 aaactggcta acgcggttgg tattggtgcg gtgaaatatg cggatctctc caaaaaccgc
     3061 accacggact acatcttcga ctgggacaac atgctggcgt ttgagggtaa taccgcgcca
     3121 tacatgcagt atgcatacac gcgtgtattg tccgtgttcc gtaaagcaga aattgacgaa
     3181 gagcaactgg ctgcagctcc ggttatcatc cgtgaagatc gtgaagcgca actggcagct
     3241 cgcctgctgc agtttgaaga aaccctcacc gtggttgccc gtgaaggcac gccgcatgta
     3301 atgtgtgctt acctgtacga tctggccggt ctgttctctg gcttctacga gcactgcccg
     3361 atcctcagcg cagaaaacga agaagtgcgt aacagccgtc taaaactggc acaactgacg
     3421 gcgaagacgc tgaagctggg tctggatacg ctgggtattg agactgtaga gcgtatgtaa
     3481 tcgatttttc gtgagagtga agcctgatca gggttagccg atcaggcttt tttattgcca
     3541 tctaaatgta ttctgaaaat ggacatgcca ttgttttctc actgttggat aagaggccag
     3601 aagcgtaata tccggcccca gggaaacgat aacggttgaa tttaaggaat accgcagtgt
     3661 ttaaatttct tgtattaaca ttaggcatta tctcttgcca ggcttacgca gaagatacgg
     3721 ttatagtaaa cgaccatgac atttcagcca tcaaagattg ttggcaaaaa aattcagatg
     3781 atgatactga cgttaacgtg atcaaatcat gcctgcgaca agaatacaat ctcgtcgatg
     3841 cgcaattaaa taaagcctat ggtgaagctt atcgttatat agaacaagtg ccacgcacag
     3901 gtgtaaaaaa acctgatacc gaacaactta acttgcttaa aaaatcacag cgagcctggc
     3961 tggattttag ggacaaagaa tgtgaattaa tcctttcaaa tgaggacgtt caggatttaa
     4021 gtgaccctta ttctgaatca gaatggctct catgtatgat catacagacc aatacgcgaa
     4081 ctcgccagtt gcagctatac cgtaactctg aagattttta tccaagccct ttgacaagag
     4141 gataattcac atctttttgg catgttttgt tgcaagctat tcctgataaa taattgcaac
     4201 aagacatcga gcctttttca ctgagttatt aaacatactc gcgagcgcgt aatttttttg
     4261 tccttcagcg ataattcaca atcacttcat tacgttgtac ctttagcggt ggaattaacc
     4321 gcccaccgcc tggcacttcc cagataaatc gcaacggttc tgctgccgct ataccggaaa
     4381 aggccacggt ggttccgctc tgcccctcta attcgacaca acgagattgc gaacacaagc
     4441 gaacccgcag tcctgaaggt gtcgggccga taagctgata acgccacgct accagcgtca
     4501 tcaatcctga agcaggttgt cgcgtagaaa gaggcgcaga cgacatcgac tcaccgcgat
     4561 gatttagcgt aattcctaca ctacttgcct gccacatccc ctccccggcg gcttgcacca
     4621 gcagcggaaa caataatatt gctaataagg ttctcattat ttgccgccaa ttgtcgccgt
     4681 catgcggata tgtcggttat cagacagttc cagattcgac aggaccacta actgcggcaa
     4741 gctgcggcgc aggaagcgag acaataatgg tcgcagcgcg tggttcacca acaatactgg
     4801 cggcgcaccc agcatctcct gacgggatag cgcttcctga gtttgcgcca gtaaacgatc
     4861 cgccagccct ggctccagtc ctcccccgcc ctgcagcgcc tgtagtaaca aacgttccag
     4921 cggtgtatcg aggccaataa catggacttc atctttgcca ggaaaccact gctgggtaat
     4981 cgcccgtccc aacgccacgc gcacgacggc ggttaattca tgtggatcgc tttggatggg
     5041 cgcatgttcc gccagcgttt cgagaatggt gcgcatatcg cgaatcggta ctttttcatc
     5101 gaggagattt tgcagcactt tatgcagtgt ggtgagcgtg acgacgccag gaacgagatc
     5161 ttccgtcagc tttggcatct cctgggcgac gcgatccaac agctgttgcg cctcctgacg
     5221 accaaacagc tctgcggcat gctggctaat gaggtggtta agatgcgttg ctaccaccgt
     5281 gctggcctca accactgtgt acccctgaat ctgcgcctgt tcttttagcg cactttcaat
     5341 ccagatagca ttcaggccaa atgccggatc gacggtcgcc tcaccaggta acgtcccggc
     5401 agcggttcca gggttaatcg ccagccagcg ccccggataa gcatcaccac tgccaatctc
     5461 cacgcctttc atcaaaatgc gatagcgggc aggttgcaga tccatattgt cgcgaatgtg
     5521 caccactggc ggcagaaatc ccatctcctg ggcaaatttc ttgcggatac tgcgtatacg
     5581 gcccaacaac tcaccatcct gctggaaatc gaccatcggg atcagtcgat aacccacttc
     5641 cattcccaga gaatcttcca gttgtacatc gttccacgtc gcttcgacaa cggtattatt
     5701 ctctgccatt tttaccggtt tgggttcggc aggcgctttt tgttcgcgtc cgcgtatcca
     5761 ccaggccagc ccgagcaatc cggcagtgaa cagcaaaaat accaggttcg gcattccagg
     5821 caccaggccg agtaaaccga gcacggcggc gcttaacaac ataacgcttg ggttactgaa
     5881 aagctgattc accatctgct cgccaacatc ctgatcggtg ctgacacgcg taacgatgac
     5941 ccccgcggcg gtagaaatca ccagcgccgg aatttgtgcc accagaccgt cgccaatggt
     6001 caatagcgta taactttccg ccgcgtgtcc catgctcatg ccatgttgca gcacgccgac
     6061 cagcaacccg ccgacaatgt taatgaccat gatgaggatc ccggcgatgg catcgccgcg
     6121 aacaaactta cttgccccgt ccattgagcc gtaaaaatcg gcttcctgag tcacttcgga
     6181 gcggcgtttt ttcgcctcat cttcaccaat caatccggcg ttaaggtcgg cgtcaatcgc
     6241 catctgctta cccggcatac catcgagaac aaagcgcgca cccacttctg cgatacgccc
     6301 ggcacctttg gtaatgacca taaagttgat gatcacgaga atgacaaaca ccacgatacc
     6361 gatagcgaaa ttgccaccaa cgaggaagtg accgaacgct tcgaccacct tccctgccgc
     6421 cgccgcgccg gtatgccctt ccattaaaat gatacgggtt gaagccacgt taagtgccag
     6481 acgcaacagc gtggtaaaca acagaatggt cggaaacgca gcaaactcaa gcgtgcgctg
     6541 ggtaaacatc gccaccagca acaccatgat cgacaaggca atattgaagg taaacaacag
     6601 gtcgagtatg aatgcgggca gtggcagcac catcatcgac aagatcaaca ggatcaaaat
     6661 cggtccggca aggatctgcc attgtgtcga tttcaggttt gcgggcaggc gcagcatcgc
     6721 ggccagatta ctcatgggtc ggtttctcgt taataaaatc cagggcttcc ggcaccggaa
     6781 gatgagtagg ttgtacaggg cgctgtccac cagccagacg ccagcgtttc agttgccaga
     6841 cccaggccag cacttccgcc accgcggcgt acagttgacc cgggatttgt tgaccaatct
     6901 ccgcatgtcg atacagcgct cgcgccagcg gcggcgcttc aagcgtcggg acgttatttt
     6961 cagcgccaat ttcacgaatg cgcagcgcga ccagccctgc acctttagcg accactttcg
     7021 gtgcgctcat tttgttttcg tcatactgca acgctaccga atagtgggtc gggttattga
     7081 caatgacatc cgctttcggc acatcggcca tcatccgacg ccgtgcagca gctcgctgca
     7141 tctgacggat ccgcccttta acatgagggt caccttcgct ttgtttgaac tcatcacgaa
     7201 tatcctgccg tgacatacgc agctttttca ggtggctgaa tatttggaaa aagacgtcaa
     7261 atcccaccat tggaatgaca ccaagcacca ccagcagtgc gcatagccct accaaatcca
     7321 tcgcattacc catggcggta atcggagact cggccatcaa gcgcatcatc tgcggccagt
     7381 gatgccagag aaaaaacccc gtcacgctgc caaccaggat ggttttcaaa attgctttaa
     7441 gcaactccgc gccagtctga gccgagaaca tccgtttaat gcccggtagc gggttgagtt
     7501 tggaaaactt cggctgcaag gatttgccgc taaataccag ccctcccagc atgaccggag
     7561 aaatgagcgc caccagcacc acgccgctaa tcagcggcag cagcgccagc atggcttctc
     7621 tgatcagcag aataatctgc ccgaggatca gattcgggtc attgataata ctgtgatcaa
     7681 aatgcagccc agcggagagc atgcccgaca atcgacgggc cagcgacaca ccgccaaacc
     7741 agataacact aacgcccacc agcaaaatca gcagtgaggt cagttcacgg gaacgcggga
     7801 tttgcccctc ttcccgcgct ttttctagtc ggtgaggtgt gggggcttct gttttgtcgt
     7861 cgctctcgtc agacacgtcg ccaatcctgg aaagagtatt aagcgtgaat gatgccagag
     7921 cgcaaagcgt tcaatggttt gagtaagggg caaaacaggc gggatttagg gcttttgctg
     7981 ccacacatca agcatagtgt gcgtttgtcg gatgcggcgt catcgcctta tcagaccgcc
     8041 tgatatgacg tggtcacgcc acatcaggca atacaaatca aaatccaaga ctatccaaca
     8101 aatcgtccac ctgatcctga ctggctacca caccggcttt gctggtatcg acctgaggtc
     8161 cattaagcaa actctggttt tcacgttttg gacgcgactc ctgttccggg atgttttcca
     8221 acagcaccat cagcaactgg cgttcgatct cctgaatgac atccatcatc cgcttaatga
     8281 cctgcccggt gagatcctga aaatcctgcg ccatcatgat ttccagcagt tgcgcgttag
     8341 taaagctggt atgcgcgggt acatctgcca gaaattgtcg tgtatctgtt accagttcac
     8401 gggcgtcggc aaggtcaatc ggatcggcaa accagtcatc ccaacgttgg gttaacgctt
     8461 ttgctgattt ctccatttga tcctgatgcg gttgtgacgc ctcaacactg ttcagcgccc
     8521 gctccgcagc ctgggcggtc atctgcacaa catagtacaa acgatcgcgc gcatcgggga
     8581 tggcttccgc cgcttcggca atggcctgat ccagccccag ttcccgcaaa ctgtcgcgca
     8641 gcatacgcgt caggctgccg atgcgcgcaa tgatatcgcc agctgaatgc tcgtcagcag
     8701 gtttgattga tggttgcatc atagtcgcat cctcacatgc ccagtttctc aaagattttg
     8761 ttgagttttt cctccagcgt cgcggcggta aatggcttca ccacatagcc actggccccc
     8821 gcttgcgccg cagcaatgat gttctctttc ttcgcttctg cagtcaccat taacactggc
     8881 aatgccgaca tcgcgccatc cgcacgaatt gttttcagca attccaggcc atccatattg
     8941 ggcatgttcc agtcggagat aacaaatcca taaccgcctg cctgcaactt attgagagcg
     9001 tcgacgccat cttccgcttc ctcaacatta ttgaatccca gctctttcag caggttacgc
     9061 actatgcgtc gcatggtgga aaagtcatcc acaaccaaaa atttaagttc tttatccgcc
     9121 atttcacact cctgatttaa atacgtatcg cctgtccggc actaattttt gccaacattt
     9181 gctggcttac ctggctaaga tcgaccactt cgcagacacc acccatattg atggcctcgc
     9241 gcggcatgcc gaacaccacg caacttgctt cgttttgcgc aagggtccat gcccccgcct
     9301 gacgcatcgc caacattccc gccgcgccgt cgttgcccat accggtcagg atcaccccaa
     9361 ccgcattacg ccccgcctgt ttggcgacag aatggaacaa cacatctacc gaaggccgat
     9421 gacggttaac cgccgggcca tcgtgaattt tgatttggta atttgcgcca ctacgcgaca
     9481 gctccatatg ccgatcgccc ggcgcaatat aggcatgccc cggcaagaca cgttctccgt
     9541 cttcggcttc tttaaccccg atctggcaaa gcttattaag tctgtcggca aaagagcggg
     9601 tgaaaccggg cggcatatgc tgggtaatta acagtgccgg gctggaaagc ggcaacggtt
     9661 gcagtacgtg acgaattgcc tcagttccac ccgttgaagc accaatcgca atcagttttt
     9721 cagaactcaa caacggcccc gccttcagcg ttgtcggtgc cgacaatggc ttatgtgctg
     9781 caaggctcgc ctttgctgcc gtacgcacct tttcagcaat catttcgtta tacgccagca
     9841 taccttcgcg aatacccagt tgcggtttgg tgacaaaatc tatcgccccc agctccagcg
     9901 cgcgcagcgt gacttctgac cctttgccag tcagggaaga aaccatcaca acgggcattg
     9961 gacgcaaacg cattaatttt tcgaggaaat ccagtccgtc catccgcggc atttcaacat
    10021 ccagcgtcag cacatcggga ttgaatttct taatcaagtc acgcgcgacc agcggatcag
    10081 gcgcggtcgc caccatttcc atgtcgctat ggctgttgat gatttctgtc atgatctggc
    10141 gcatcagtgc cgaatcatcg acagataaca ccctgatttt gctcatcgtt aatccttact
    10201 tagcgcatac accgtctgac cacgcagcgt gaagcggcgc tcaaggtggc taaagttttc
    10261 agagtgaccc gcaaacagca atccgtcggg tttaaggagc ggaacaaagc ggcgcaaaat
    10321 ctcctgctgg gtagtttgat cgaagtagat catgacgtta cgacagaaga tcgcatcaaa
    10381 cggccccggc acggtgtact gtttcgccag tagattcagc ggggcaaaat caacatagtt
    10441 cgccagctcc tgacgcacgc gtaccagccc ttcatgcggc cccgtccctc gcatgaaata
    10501 ccgttgcagt tgctgcggcg tcaggttttt caactcttca tggcgataga taccgcttct
    10561 ggctttttcc agcacttcgg tgtcgatatc actggcaaac actttccagc gtccgggcgc
    10621 ggtgcccaat gtgtcagcca gcgtcatcgc aatgctgtac ggctcttcgc cggtcgaagc
    10681 cgccgcgctc catacgcgat actcgccaga acggcgacgt gcgtgatccg cgagcagagg
    10741 gaaatgatgt gcctcacgga aaaatgccgt cagattcgtg gtcagcgaat tgataaacgc
    10801 ctgccactca ccgctgtgct gattagattc cagcaagttc agataatgac cgaaatccgt
    10861 cagtcccagc gaacgcaaac gacgaaccag tcggttgtaa accatgtcgc gtttatggtc
    10921 agccagaacg atcccggctc gttgatagat caattgactt atccgccgaa aatgcgcgtc
    10981 ggaaagcgcc aggcgctcgg tcatctgtaa caataaagac gtttgcccac agggcagaga
    11041 tgaagtcata gcgccttctc aatcacttca ggataccact ggcgcaattt gtaactgcac
    11101 cgactcatgt cgtgctactt catgttcttc aagggtaaat accgccacac gcgacgaaag
    11161 atggtcggcc tgattcgcca gttgttccgt tgccaccgcc gcttcttcta ccagcgaggc
    11221 gttctgctga gtcacctgat ccatctggct gacagcctgt gcaacctgct caatcccccg
    11281 ctgttgttct tccgacgcag aggcaatttc tcccataatg tcgttcacgc gggtcaccga
    11341 actgacaata tcgatcatgg tcgcggcggc gttattcacc agtttcgaac cctgctggac
    11401 acgattgact gactcttcga tcagcccttt gatctctttt gctgcctgcg cgctacggct
    11461 ggcaagattg cgcacttcac ttgccactac cgcaaaacca cgcccctgct ctccggcgcg
    11521 agccgcttcc actgccgcat tcagggccag aatattggtc tggaaagcaa ttccgtcgat
    11581 aacgctgata atgtcgccaa ttttttgcga gctggtggcg atctcctgca tggtgtgagt
    11641 catggtactg acctgaacac cgcccgcctg cgccgttgtc gcggcatttt ttgccagttc
    11701 cgacgcctgt cgtgcgttat cggcgttttg ccctaccgtg gcggttaatt gctccatact
    11761 ggcggccgtt tgtgccagcg atgccgcctg ctgttcggta cgacttgaga gatcgttatt
    11821 gcctgcgaca atctccgcga taccaatgtg catctcctgg cttcccttac gcacatcact
    11881 taccgtccca cgcaaagcct gctgcatggt cttcagactg gcaaaaatgg cggtgatctc
    11941 attacgacca tataccgcaa tcggacgcgc cagattaccc gcagcaatgc tgtcaaaatg
    12001 gctaccgata atggccagtg gttgaacaat catcttgcgc gtccaccaca gcgcactgct
    12061 gatgtagatc gccgcaacaa taatcatgct gataaacacc agtgccgaaa tctgatagtt
    12121 acgctggctt tgcgcactgg cggcttccag cacatggttg atctccagct gccaggcctc
    12181 aaagttaacg tcaaacgcat tctgtgatcc ctgcaccggc gcagtgagga aatccgaaag
    12241 ttgattactt tcaagccagg tcgcctgatg ttcgagatcg ttgtgccagc gggcaaaact
    12301 tttctccgtc tctttttgca atcccctgac gtgctcgttg cccgcagtca tcgccataaa
    12361 acttttaaac agcgtggtgg attgcgtcag actggcgcgc gccgtcgtca tcaacgtttt
    12421 aatgtcatcc gccggatagc taagtgccgt cagagtgccc gctttgttca gcgcggtact
    12481 ggcctgtaac attaccgccc gagtttgcgc taatgccgca cgttgctgat tgctctgctc
    12541 gacctgattc agtcgttgca aatcgtcgcg aaatgcccaa aaagacatgc cgttactgcc
    12601 aatctgcaag atcccgcaga gaatcaaaat taaaaacagc gtggtcgaaa ttcgaatacg
    12661 attaaacatc aacgctcccc atcaggcggc aatgaccgcg ttagtaaata ctcgtcaaaa
    12721 tgtttcccag tttggatctt gttcagcaat tcgcagtcgt ggctgtgccg gtggttgctc
    12781 actggcagga cgggatggtg tttgcggttt attggtgagt gggctggctg ccagacggaa
    12841 cgcggaaacc gcttgcgtta aacgactcgc ctgttcttcc agcgcagcgg cggcggcagc
    12901 tgattcctgc accagcgatg cgttctgttg cgtgacgcga tccatttccg aaaccgccaa
    12961 tgcgacttga tcgatgccac ggctctgttc atccgatgcc gatgcaatct cgcccataat
    13021 gtcagtcacg cgagtgacag cattgacgat attgttcatt gtttccccgg cgctttcgac
    13081 cagcaccgaa ccggtatcaa cgcgtgagac ggagtcttca atgagggctt tgatctcttt
    13141 tgccgcctgg gcgctgcgac tggcaagatt acgcacttca cccgccacca cggcaaaacc
    13201 acggccctgt tcacccgcac gcgcggcttc aaccgcggca ttcagcgcga ggatattagt
    13261 ctggaaggca ataccgtcga taacgctgat aatgtcggca attttcttcg aactatcggc
    13321 gatctcatgc atcgttttca ctacgccatc caccactttg ccgccgtgct gggcggtgtc
    13381 ggaggcactt tgcgccagtt gcgaggcctg gcgggcgtta tcggcgtttt gcttcactgt
    13441 cgcggtgagc tgctccatgc tggcggcagt ttcttccagc gcggatgcct gctgttcagt
    13501 acgggaggaa agatcggtgt tgcccgccgc aatttcacgg gtaccggcat agatggcatc
    13561 tgaaccttcg cggacatgag tgacggtgtc agtcaaagag cgttgcatat gtgaaacgct
    13621 ctgcgccagg tcgcccattt cactgcgccc gtcaatggtc agggtattcg ccaggttacc
    13681 accggcgatt tcgcgaatgt gagcaataat ttttgccagc ggagtaagca acatacggcg
    13741 aatgccgtac cacgccacca gcagaatcaa taccaccacc agcgcgataa ccgccagttg
    13801 ccactgggca aatcggtaat catctgcgtt gtcagtgacg atatcgcgat acagtttttc
    13861 actgctgagg gcgtactgag caaacgcttc gcccattgca ttttgcattc cctgggttgg
    13921 ctgagcgaaa taagctccag tattgccata atctagataa tcaatcagtt cagttaacgc
    13981 tgtgtaatag tttttatatt tttcatcaat attacgactg gtagcgacca tttcaggtaa
    14041 cggtgccatg cttttgaatt ttttataatg cgtcgctgcc tgcgccaatg ttttcctggc
    14101 gctatcgagc aattcaactt tggcgttact ttgttgattg gaggaatcca tcatcatccg
    14161 caccgctgaa cgactcaggt taatacgcgt ttgcagcatt aaatcccagg ttgacgtcag
    14221 ctcgccctgc tgttcccgta attgattgga aaccacaaag ctcttctggc tatggtgaag
    14281 ggaagaaaaa aacagactgc cggaaataag ctgtaacagt gcgaataccc ccagcaccat
    14341 taccaacagc gtgactacgc ggatacggtt aatcataagg caccttcctg aaaacaagtt
    14401 gatctcgtta tcggcaagaa ggggggaaac tttattgctg atgccacccg ccgcgaaatt
    14461 gaaataaaaa acccgatgcg cagatcatcg ggttcatttc aattgaggaa atcgggagaa
    14521 ttacgccact tctgacgccg cgctatctaa cagcgccatc tcttcgctgt tcagcagttt
    14581 ttcgatgttc accagaatca acatccggtc gcccagtgcg cccagtccag tgagatattc
    14641 tgttgaaagc gtcacggcaa attccggtgc cggacgaatt tgctccgccg tcaatgaaag
    14701 cacgtctgag acgccgtcaa ccacgatgcc gaccacccgc tgtccgagat tcaggacgat
    14761 aactaccgtg ttgtcgttat agtccacatc cacctggctg aacttaattc gtaagtcaac
    14821 aatcggcaca ataacgccgc gcagattcgt gacgcctttg ataaacgctg gcgtgttcgc
    14881 aatccgtgtt acctgatcgt agccacggat ctcctgcact ttcaggatat caataccgta
    14941 ctcttcatca ccaagggtaa ataccagaaa ttcctggcct gacggctcgc tggccagctt
    15001 tgttacattc gtcataccgg tcatattgtt acctttttac tcattcaggc ggcggtgttc
    15061 gccatacgtt gttcgcggtt tatcgcctgc aaggcggaga catcaacaat cagtgccacg
    15121 ctgccgtcgc caagaatggt cgcagcagaa atgccgggga ctttgcgata gttactttca
    15181 aggtttttaa ccacaacctg gtgttgacca attaattgat ccaccagcaa ggcgtagcgg
    15241 cgaccgccac tttgtaagat caccacaatt ccctgggtgg cttcggtttt cgcgcccgcg
    15301 acgttgaaca ctttccacag ttcgacgatg ggcagatatt caccccgcac ttccagcacc
    15361 cgctcgccgc cggccagtgg atggagatcg gcttcacggg gttgcagtga ttccataaca
    15421 gcattcagcg gcagaatgaa aacttcatcc gcaacgcgta cggacatgcc gtcgaggatg
    15481 gccagcgtca gcggcagtaa aatgcggatc gtagtgccag taccctgctt cgactggatt
    15541 tcgacatgac cgcccatctc ctggatatta cgtttaacga cgtccatgcc gacgccgcgc
    15601 ccggagacgt cggtgacctg ctctgccgtg gagaagccag gtgcaaatat cagcatcgcg
    15661 acttcgtcgt cgctcatgtt ttcgctgaca gtcaaacctt gcgaggccgc ttttgccaga
    15721 attcgctcac ggtttagccc cgccccatcg tcggtcactt caatgcaaat gttgccgccc
    15781 tgatgttcgg cagacagaat taaatttccg acgctgtttt tacctgcggc gagccgtttt
    15841 tctggcagtt caataccgtg atcgaggcta ttgcgtacca ggtgggtcag cgggtcgata
    15901 atgcgttcta tcaggctttt gtcgagttca gtagaactgc ccaccagcgt cagttctacc
    15961 tgcttgccga gttttcccgc cagatcacgc accagccggg gatagcgact aaaaacatat
    16021 tccatcggca tcatgcgaat cgacatcact gattcctgca aatcacgggc gttacgttgt
    16081 aactgcccca tgctggttat caaatcacca tgattaaccg ggtccagttc gctggaacgc
    16141 tgggcaagca tggactgggt gataaccagc tcgccgacga ggttaattaa ttgatcaacc
    16201 ttttctaccg ctacacggat gctggtggat tcattgctgc gcgtcgtttt ttcccgctcc
    16261 acgcggccgg ttggcgcttg ttcggctgcc agtttaagca ctggtggggt ggatattttt
    16321 ggcgagactt ctactgtttc aaaggtaatc tgatcggctt caatcacaaa acagagtacc
    16381 gctgtgatgt catcttcggc gatgtcgccc ggtaatattg ccgagagcga atccgcccct
    16441 ttcaccacgt cagttaacgt tgtcagatgt cccagttctt cttccagcag gtcgacttcc
    16501 ccggccttca ggcgcgaaag gataattcgt cgcggcgact gactgcgact ctgctcatct
    16561 tgcggttcac ttttggcaac cacacttaat cgggtcactg cggatggcgt ttcgcctttc
    16621 gcttctaatg ccagttgacg caaggcctgg cagatataat cgaagctggc ggcatccggc
    16681 tcttgcgact gtttataagc gtcgagctgt tcttgcatga tgtccttcgt ttccaaaaac
    16741 agattgataa tgtcggtgtt gagttgcatc tcacctcgtc tggcttcatc gagcaggttt
    16801 tccatcagat gcgtggtttc ctgcaaaacg ctgaagccaa aagttcctgc ccctcctttg
    16861 atcgagtggg cagcccgaaa gatggcattc aattgttcgg catctggcgc ttccggctgc
    16921 aaaaccagca aatgctgctc catgtcagcc aacagttcgt ccgcttcatc aaaaaatgtc
    16981 tgataaaaat cgcttatatc catgctcacg ctgtcacctc ggttcggctg atggcattgt
    17041 gggaacactg acctgtggtg caacctcagg tttttccagg gcgcttactg gctcattctg
    17101 gctttcggcg ttttcatgca aaatggcctg ttcggcttgt ttgttcagta ccagcaggct
    17161 gatgcgacgg ttgacggcat catcaggtcc gcgatcgctt aagcgcatcg ttgccgccat
    17221 gccgacgaca cgtaacactt tgccgctatc caaccctccg accatcagtt cgcggcggga
    17281 tgcattggcc cgatcggcag aaagctccca gttgctatat cctttctcac cgctggcgta
    17341 ggggaaatca tcggtatgac ctgaaaggct aatacggttg ggaataccgt tcagtacagg
    17401 cgcaatggcg cgcagaatgt cgcgcatata gggttcgaca tcggcactgc cggttctaaa
    17461 catcgggcga ttctggctat cgatgatctg aatacgtaga ccttcctgga ccagatcgat
    17521 tttgagatgg ggacgtaacg cccgcagttt cggatcggac tctatcaact ggtcgagatc
    17581 accccgcaat ttccgcaatc gactttgctc catgcgtttt ttcagctctt cgatgttcgg
    17641 ctgcttattc acttccccct ggctttgggt gtaatcatca ccaccgccgg gaattgggct
    17701 ttcactatta gaaatgcgat cgccgcccgt aaccgcagtc gccagtggag tccggaagta
    17761 ctccgcaatc tgaatcagct cttttgggct ggagatggag atcagccaca tcaccagaaa
    17821 aaaggccatc atcgcagtca taaagtcggc ataagcaatc ttccacgatc catgtgctgc
    17881 cccgtggctt ttggctttgc gtcgtttgac gacaataatc ggatgcgctt gattcttcat
    17941 gcttcctcgg ttgtcgtctg ttgttgcgga tttttcaccg cacgcacatg ctcttccagt
    18001 tcaataaacg acggacgttc gctggaatag agcgttttgc gaccaaactc aacggcgata
    18061 ggcggtgcgt aaccgttcag attagaaagc agagtgactt tgacgcactg catcattttg
    18121 ctggtttcgg cgcttttctg acgtaaaaca gtcgctaatg gggaaataaa tccgtaagcc
    18181 aataaaatgc cgaggaaagt ccccaccatc gcatgtgcga taagcgcacc cagctcggcg
    18241 gcaggacgat cggctgaacc taacgcgtga acgaccccca ttacagccgc aacaatacca
    18301 aacgccggaa gtgagtcccc gaccagcgcc agactgttcg ccgggacttc tgcctcgctt
    18361 tcgtgcgtct caatctcttc atccatcagg gcttcgattt cgaaggtgtt catgtgaccg
    18421 ctgataatca ggcgcagata atcgacgata aaatcaagca tgacgctatc cgcgaggatg
    18481 cgtgggtagc tggcgaagat ctcgctctca cggggatttt caatatcacg ttccagcgaa
    18541 aacatcccca tctgccgcga tttcgccatc aaccgataaa gcagagccag cagatccata
    18601 tacattgctt tggtgtattt ggagcgacga aacagcaacg gcagcgcctt cagcgtgcct
    18661 ttaatcgctt tgccattatt gccgacgata aacgacccaa tccctgcacc ggcaataatc
    18721 accagttcag cgggttgata gagtgctcca aggcttccac cggtcatcaa ataaccgccg
    18781 aaaactgtac cgagaacaac caggtaacct aataagataa gcacgacatc atccttccac
    18841 tgttgaccat gacaggatgt tcagtcgtca ggcgttaacg cgcgattggg gcaaaaaaaa
    18901 gcagcggtac gtcgttaccg ctgctggaat gttgcgcctc accgtatcag ttaaacagcc
    18961 tgtactctct gttcatccag cagttgtggg ataatatcgg caggattctg ggaaagttta
    19021 cgtcttttta ctgcccggga tggcggttga cataagctgc aggcaaagct gccaacaggc
    19081 tggtgagcgt gggtaataaa attgccgccg cagcagttgc agctggaaag ttgcagtaat
    19141 ccactttcaa caaaccgcac caatgtccag gcacgggtta atgccagcag tggtccttct
    19201 tctgcttgtg ggcactgttc aaggtataaa cggtaggctt tgatcaccgc atcgacgcca
    19261 ttacacaaac cggttttcag taaaaactgc catgcattac agaacatcga agcatgaacg
    19321 ttttgttccc aggtcataaa ccagtcggtt gagaatggca gcatgccttt cggcggtggg
    19381 cttccgcgca gttctttata aagttttatc aggcgtccgc gacttaaatg tgtttcgctt
    19441 tccagcatct gcaaacgagc gcccagggtg atcaattcca ttgccagctg aatatcccgc
    19501 gcttcctgaa caatgctttt ttcactcatg atcaggccct tttcttgcgc agcgcttctt
    19561 caggctgatt aacatcattc agcaagcgtg ttgagagcat gatgccggta tgaatttgct
    19621 ggagatcgtc aacgcgggaa tcttgcgtca actgagtaat cgtctggtgg ctgtcaaaac
    19681 ggaagtgaca aaccagttga ttggtttctg ccagcttaac catttgcgga agagtcagtg
    19741 ccgctaacgt tgtcgccatt tcttcattta tgccgagacg aaacatagcg gacgctttgt
    19801 cctgaacaat caaacgctgt gcaagtagta aatatgacaa gttgatgtca taaatgtgtt
    19861 tcagcaactc ggaggtatgc attattccca cccagaataa ccaactttat ttttatgcgg
    19921 tttcaccgca ccccgtgatg tcgccgggaa gccccggtaa aaaataatta gcattagaat
    19981 agttgcgata agctgcaata agcagaacca cctttttggt ttaatatgtc cttacaaata
    20041 gaaatgggtc tttacactta tctaagattt ttcctaaatc gacgcaactg tactcgtcac
    20101 tacacgcaca tacaacggag gggggctgcg attttcaata atgtgtgatg cagatcacac
    20161 aaaacactca attacttaac ataaatgtat aagtcatact tttgttttgg gtgtatttca
    20221 atctgttaaa aagtttttcg ctacgctagc aagcaaaaat gaaacaggaa taatcgaaat
    20281 gggatgttgc gcacagtcaa aataactcac cgtaaataat catctgctat aaataatcac
    20341 tttcatgcaa taccagataa gctattttta aacagacact taccgcacaa caaactaatt
    20401 aaatacaaag aaaggcaaca atcaacttaa tgttaatgaa atgttttaca tatattaacc
    20461 acttgttt
//
LOCUS       DAPHKZ010000078        20335 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.078, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000078 DAPHKZ010000000
VERSION     DAPHKZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20335
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.078"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(142..315)
                     /locus_tag="RH288_002976"
     CDS             complement(142..315)
                     /locus_tag="RH288_002976"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032015.1"
                     /translation="MMIYVVDPVLLKAHNGLRIQMNGTTSYLACVQVINTIHSNFLLL
                     TKLRALLIDKSGR"
     gene            408..2321
                     /locus_tag="RH288_002977"
     CDS             408..2321
                     /locus_tag="RH288_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014883662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDV4032016.1"
                     /translation="MNHWYTIKAAGVRGAAEISIYEEIGGFGITAKQFAEDLKALGDV
                     SHIDLRIHSPGGDVFEGIAIYNLLRNHPAEITVYIDGVAASMASVVAMAGDRVVMPEN
                     AMMMIHKPWGISGGNAGDMRDYADLLDKVETVLIPAYARKTGKSAQEITAMLEDETWM
                     DGKECLKQGFADELLPSVRAMARIESKRTGDFSHMPETIKGMITPPQGAANIAGNEQK
                     RINGISEVFSLFGSRYDGIKMACLEDASCTPEMAREKLLNEMGRESTPSNKNTPAHIY
                     AGNGNITGDAIRQGLYSRLGYERPERGNPYAMMSLFEMAQASLTDRGISVGGFLNRSQ
                     VVNAAFTHSSSDFSHILAGGAEKSVLKGWQDSGETFQKWTRTGSLSNFHEAKRVGLNG
                     FSKLDKVPEGAEYKYITTRDKGVPIALATYGNIFSVTRQAIINDDLTQLTTIPMAMGR
                     AAARTVGNLVYLLLTSNGKFTDGKALFHADHKNLIAKDMDMEGLNEARKLMRLQEDAN
                     GDSLNITPAFVLVPAALESAAHRAILSSSSLFPVDGEGTINQNPGIINVVKDMAEVIV
                     EPRLDKNNNKEWYVAAAKGMDTIEVAYLDGIDTPYLEEQEGFTVDGVAWKVRIDAGVA
                     ALDYRGLLKSSGA"
     gene            2529..3071
                     /locus_tag="RH288_002978"
     CDS             2529..3071
                     /locus_tag="RH288_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDV4032017.1"
                     /translation="MKSHLMNKKNMAQSCRVSATAFDKWGVTPVERKGREAFYDVASV
                     IDNRVSNAINQITDDKGEIDNDELLRVRIRLLTAQAEAQELKNERERGDVISTEFCIY
                     ALSKLASQISSIMDSLPLTMQRRFPQMTPAMLDGLKKEVVRACNACTKLDENIPRMLS
                     DYLMETTGNVSDKFQPDKDK"
     gene            3323..3604
                     /locus_tag="RH288_002979"
     CDS             3323..3604
                     /locus_tag="RH288_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032018.1"
                     /translation="MTETEALGIIRSITGISQQADEQATQPDTVTAENYARVMAEVMR
                     RDGIELNGVDIRNIRTRVLEMLSYRRRVQMYQEKEKITYQWKKPERLRR"
     gene            complement(4239..6830)
                     /gene="yejO"
                     /locus_tag="RH288_002980"
     CDS             complement(4239..6830)
                     /gene="yejO"
                     /locus_tag="RH288_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311108.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter YejO"
                     /protein_id="HDV4032019.1"
                     /translation="MHQSGSVSLCRSAISVLVATALYSPIALASTVEYGETVDGVVLE
                     KDIQLVYGTANNTKINPGGEQHIKEFGVSNNTEINGGYQYIEMNGAAEYSVLNDGYQI
                     VQMGGAANQTTLNNGVLQVYGAANDTTIKGGRLIVEKDGGAVFVAIEKGGLLEVKEGG
                     FAFAVDQKAGGAIKTTTRAMEVFGTNRLGQFDIKNGIANNMLLENGGSLRVEENDFAY
                     NTTVDSGGLLEVMDGGTVTGVDKKAGGKLIVSTNALEVSGPNSKGQFSIKDGVSKNYE
                     LDDGSGLIVMEDTQAIDTILDKHATMQSLGKDTGTKVQANAVYDLGRSYQNGSITYSS
                     KAISENMVINNGRANVWAGTMVNVSVRGNDGILEVMKPQINYAPAMLVGKVVVSEGAS
                     FRTHGAVDTSKADVSLENSVWTIIADITTTNQNTLLNLANLAMSDANVIMMDEPVTRS
                     SVTASAENFITLTTNTLSGNGNFYMRTDMANHQSDQLNVTGQATGDFKIFVTDTGASP
                     AAGDSLTLVTTGGGDAAFTLGNAGGVVDIGTYEYTLLDNGNHSWSLAENRAQITPSTT
                     DVLNMAAAQPLVFDAELDTVRERLGSVKGVSYDTAMWSSAINTRNNVTTDAGAGFEQT
                     LTGLTLGIDSRFSREESSTIRGLIFGYSHSDIGFDRGGKGNIDSYTLGAYAGWEHQNG
                     AYVDGVVKVDRFANTIHGKMSNGATAFGDYNSNGAGAHVESGFRWVDGLWSVRPYLAF
                     TGFTTDGQDYTLSNGMRADVGNTRILRAEAGTAVSYHMDLQNGTTLEPWLKAAVRQEY
                     ADSNQVKVNDDGKFNNDVAGTSGVYQAGIRSSFTPTLSGHLSVSYGNGAGVESPWNTQ
                     AGVVWTF"
     gene            7150..7797
                     /gene="narP"
                     /locus_tag="RH288_002981"
     CDS             7150..7797
                     /gene="narP"
                     /locus_tag="RH288_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HDV4032020.1"
                     /translation="MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASA
                     IDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAG
                     ADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ"
     gene            complement(8008..9060)
                     /gene="ccmH"
                     /locus_tag="RH288_002982"
     CDS             complement(8008..9060)
                     /gene="ccmH"
                     /locus_tag="RH288_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis thiol:disulfide
                     oxidoreductase CcmH"
                     /protein_id="HDV4032021.1"
                     /translation="MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCP
                     KCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIVDYMVARYGNFVTYDPPLTPLTV
                     LLWVLPVVAIGIGGWVIYARSRRRVRVVPEAFPEQSVPEGKRAGYVVYLPGIVVALIV
                     AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKN
                     PGDIEGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDPNDNR
                     LGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE
                     RSIAQAMQHLSPQESK"
     gene            complement(9057..9614)
                     /gene="dsbE"
                     /locus_tag="RH288_002983"
     CDS             complement(9057..9614)
                     /gene="dsbE"
                     /locus_tag="RH288_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HDV4032022.1"
                     /translation="MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKP
                     VPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVG
                     MNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
                     GDLNPRVWEEEIKPLWEKYSKEAAQ"
     gene            complement(9611..11554)
                     /gene="ccmF"
                     /locus_tag="RH288_002984"
     CDS             complement(9611..11554)
                     /gene="ccmF"
                     /locus_tag="RH288_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis heme lyase CcmF"
                     /protein_id="HDV4032023.1"
                     /translation="MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAW
                     LLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWT
                     LLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARG
                     HKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVA
                     MTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYS
                     VERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRY
                     YNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGG
                     LLCLFDPRYRKRVSPQKTAPEAV"
     gene            complement(11551..12030)
                     /gene="ccmE"
                     /locus_tag="RH288_002985"
     CDS             complement(11551..12030)
                     /gene="ccmE"
                     /locus_tag="RH288_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HDV4032024.1"
                     /translation="MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEIL
                     YGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDL
                     FREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS"
     gene            complement(12027..12236)
                     /gene="ccmD"
                     /locus_tag="RH288_002986"
     CDS             complement(12027..12236)
                     /gene="ccmD"
                     /locus_tag="RH288_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HDV4032025.1"
                     /translation="MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHR
                     AILRGVAQQRAREARLRAAQQQEAA"
     gene            complement(12233..12970)
                     /gene="ccmC"
                     /locus_tag="RH288_002987"
     CDS             complement(12233..12970)
                     /gene="ccmC"
                     /locus_tag="RH288_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmC"
                     /protein_id="HDV4032026.1"
                     /translation="MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFA
                     PADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAV
                     FTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
                     ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTL
                     MRMRNLILLMEKRRPWVSELILKRGRK"
     gene            complement(13012..13674)
                     /gene="ccmB"
                     /locus_tag="RH288_002988"
     CDS             complement(13012..13674)
                     /gene="ccmB"
                     /locus_tag="RH288_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HDV4032027.1"
                     /translation="MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQ
                     LLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWM
                     VTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
                     LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRIS
                     IQ"
     gene            complement(13671..14288)
                     /gene="ccmA"
                     /locus_tag="RH288_002989"
     CDS             complement(13671..14288)
                     /gene="ccmA"
                     /locus_tag="RH288_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HDV4032028.1"
                     /translation="MLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLL
                     RLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDG
                     DTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVN
                     GVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAA"
     gene            complement(14307..14909)
                     /gene="napC"
                     /locus_tag="RH288_002990"
     CDS             complement(14307..14909)
                     /gene="napC"
                     /locus_tag="RH288_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HDV4032029.1"
                     /translation="MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIR
                     KLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
                     QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF"
     gene            complement(14919..15368)
                     /gene="napB"
                     /locus_tag="RH288_002991"
     CDS             complement(14919..15368)
                     /gene="napB"
                     /locus_tag="RH288_002991"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HDV4032030.1"
                     /translation="MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQE
                     GAIRMPKEQDRMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK"
     gene            complement(15365..16228)
                     /gene="napH"
                     /locus_tag="RH288_002992"
     CDS             complement(15365..16228)
                     /gene="napH"
                     /locus_tag="RH288_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HDV4032031.1"
                     /translation="MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPW
                     FGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHLPATVALTGAVIITVLYALAGKR
                     LFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVVILVGSALTGTLIWEWI
                     NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITV
                     AATDRQKCNRCMDCFHVCPEPHVLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFT
                     ITTRWSSGAKS"
     gene            complement(16215..16910)
                     /gene="napG"
                     /locus_tag="RH288_002993"
     CDS             complement(16215..16910)
                     /gene="napG"
                     /locus_tag="RH288_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HDV4032032.1"
                     /translation="MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGV
                     RLRPPGAINENAFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALDREIESIDDARMGLAVLVDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGNNGKS"
     gene            complement(16917..19403)
                     /gene="napA"
                     /locus_tag="RH288_002994"
     CDS             complement(16917..19403)
                     /gene="napA"
                     /locus_tag="RH288_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic nitrate reductase subunit alpha"
                     /protein_id="HDV4032033.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLL
                     RMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAE
                     MHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYII
                     QNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVA
                     EYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPS
                     GTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVS
                     DPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEDLLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNKLTLDATDPLSKETDFKKCAVKLEKV"
     gene            complement(19400..19663)
                     /gene="napD"
                     /locus_tag="RH288_002995"
     CDS             complement(19400..19663)
                     /gene="napD"
                     /locus_tag="RH288_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HDV4032034.1"
                     /translation="MHTNWQVCSLVVQAKSERISDISTQLNAFPGCEVAVSDAPSGQL
                     IVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP"
     gene            complement(19653..20147)
                     /gene="napF"
                     /locus_tag="RH288_002996"
     CDS             complement(19653..20147)
                     /gene="napF"
                     /locus_tag="RH288_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HDV4032035.1"
                     /translation="MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACI
                     NACENNILQRGAGGYPSVNFKNNECSFCYDCAQACPESLFSPRHTRAWDLQFTIGDAC
                     LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
                     LHAH"
BASE COUNT         5051 a         5633 c         5054 g         4597 t
ORIGIN      
        1 atataaataa atccgttttt cacctgccag gtggagttgc cagtgtcaaa acgtgttcag
       61 atggcgggat atttatgccg gattttctcc ggcttttttg tgtctgaatc tgactaatct
      121 gttttcatga tagaaatata tttatctacc acttttatcg atcaataatg cgcgcagttt
      181 agtcagtaag aggaagttac tgtgaattgt attaatgacc tgaacacagg cgaggtaaga
      241 ggtggttccg ttcatctgga tgcgcagacc gttatgcgcc ttaagcagta caggatcgac
      301 cacataaatc atcatcctgg ccaaccatta ccaggtgtgg cgcagattgt cagacacgca
      361 gttaacgcgt ggcttgataa gaatggtttt gcatctgggg gtgagcaatg aatcactggt
      421 acaccattaa ggcggcgggt gttcgcggag cggcagaaat atccatctat gaagaaattg
      481 gcggcttcgg tatcaccgcg aagcagtttg cggaagacct gaaagccctg ggcgatgtct
      541 cacatatcga cctgcggatc cattcgccag gtggtgacgt gtttgaaggc atcgccatct
      601 ataacctgtt acggaatcat ccggcagaaa ttacggttta tatcgatggt gttgcggctt
      661 caatggcttc ggttgtcgca atggctggcg atcgtgttgt gatgccggaa aacgccatga
      721 tgatgataca taagccgtgg ggtatctctg gcggaaatgc tggtgatatg cgtgattatg
      781 ctgatttgct ggataaggtg gaaaccgtgt taatccctgc ttatgccaga aaaacgggca
      841 aatcagcaca ggaaattacc gccatgctgg aagatgaaac ctggatggac gggaaagaat
      901 gccttaagca aggttttgct gatgaattgt tgccatccgt cagagcaatg gcgcgaattg
      961 aatcgaaacg cacaggagat ttttcacaca tgccggaaac cattaaagga atgattaccc
     1021 cgccacaggg agcagccaat attgctggta atgaacagaa gcgcatcaac ggaataagtg
     1081 aagtgtttag cctgttcggc agtcgttacg acgggatcaa aatggcgtgc ctggaagatg
     1141 catcatgtac accggagatg gcccgtgaaa agttgttgaa cgagatgggg cgcgagtcca
     1201 cgccatcaaa taaaaatacc ccggctcata tttatgccgg taacgggaac ataacaggtg
     1261 atgcaattcg tcaggggctt tattctcgtc tcgggtatga acgcccagag cggggaaatc
     1321 cttacgcgat gatgagcctt tttgaaatgg cccaggcatc actaacggat cgtggtatca
     1381 gtgttggcgg ttttttaaat cgctcgcagg tcgttaatgc agctttcaca cacagcagca
     1441 gcgatttttc tcatattctg gctggtggtg ctgaaaaatc agtactgaaa ggctggcagg
     1501 acagcggcga aacgtttcag aaatggacgc gtaccggatc gctttcaaac tttcatgaag
     1561 caaagcgcgt tggtctgaat ggtttttcaa agctggataa agtaccggaa ggtgcggaat
     1621 ataaatacat caccaccaga gataaaggtg tacctattgc gctggccacg tacgggaata
     1681 ttttttccgt tacccgtcag gccattatca acgatgacct gacccagtta actacaatcc
     1741 ccatggcgat ggggcgtgcg gccgccagaa cagtaggtaa tctggtttat cttctgttaa
     1801 ccagcaacgg caaatttacg gatggtaaag cgttattcca tgccgatcat aaaaatctta
     1861 ttgcgaagga tatggacatg gaggggctta acgaagcccg taagctgatg cgactacagg
     1921 aggatgccaa cggcgactcc ctgaatatta cccccgcttt tgttctggtc cctgctgcgc
     1981 tggagtctgc cgcacatcgc gccattctgt catcgtcatc actctttccg gttgatggtg
     2041 agggcactat caatcagaac cccggcatca ttaacgtggt gaaagatatg gctgaggtta
     2101 ttgttgagcc acgtcttgat aagaacaata acaaggagtg gtatgtagcc gcagcgaaag
     2161 ggatggacac gatagaggtc gcttatcttg atggtattga tacgccatat cttgaggagc
     2221 aggagggctt tactgttgat ggtgtcgcct ggaaggtgcg catagatgca ggtgttgcgg
     2281 ccctcgatta tcgtggacta ctgaaatcga gtggagcatg acaacaaggg cggcgatagc
     2341 cgcctttttt tacgggtcct cccggtggag tggccttacc acggggcggc agacgcgcgg
     2401 gttttcgcta tttatgagcc tttttcgggt gctggtggtg gttttgttgt tcgctctatc
     2461 tctatgaata aaaagggaaa gataaaacaa atacaccaac ctgaaacatt acttaagtgg
     2521 ggatattgat gaaatcgcac ctgatgaaca aaaaaaacat ggcgcaaagc tgccgtgtaa
     2581 gtgcgacagc gttcgacaag tggggagtga ctcccgttga acgtaaaggc cgcgaggcgt
     2641 tttatgatgt tgccagcgta atagacaatc gggttagcaa tgcaattaac cagattacag
     2701 acgacaaagg cgagattgat aatgatgagc ttttgcgagt caggatcaga ttgctgacag
     2761 cgcaggcgga ggcgcaggag cttaaaaacg agcgcgaacg cggcgacgtg attagtacgg
     2821 aattttgtat atatgcgctt tcaaaactgg cgagtcagat ttcatctatc atggacagcc
     2881 tgccgcttac catgcaaagg cgcttcccac agatgacccc cgccatgctg gatggcctga
     2941 aaaaagaagt tgtcagagcc tgtaacgcat gcacaaaact tgatgaaaac atcccgcgaa
     3001 tgctgtccga ttatctgatg gaaactaccg gaaatgtgtc tgataagttt cagccggata
     3061 aagacaagta acgtagtgca caatgaccga agccagttta ctgactggct ttcagcgttg
     3121 cgctggtggg agttatgcgt cagtgatgaa caaaaaataa tcgaaatcga caccgaaaaa
     3181 taaaacatca agtcatatca atatattgca ttggtggtga tgacgaataa aaatgcaaaa
     3241 actagccttt ttccgcgatg ctcccgcccc gtggcagggc accccaccag gaggacccgc
     3301 catcactatg gaggccatga ccatgaccga gaccgaagcg ctcgggataa tccgcagtat
     3361 taccggaatc agccagcagg ctgacgaaca ggccacgcag ccggatacag tcaccgctga
     3421 aaattacgcg cgtgtgatgg ctgaggtgat gcgccgtgac ggtatcgagc ttaatggcgt
     3481 ggatatacgc aacatacgca ccagagttct ggagatgttg tcgtaccgtc gccgcgtgca
     3541 gatgtaccag gagaaagaaa aaattacgta ccagtggaag aagccggagc ggttacggcg
     3601 ataaatattg gtgggagggg cggatcaaat ccttgcagcc atggctgccc gggaccgacc
     3661 gcctaccctt gttcacatcg ccgcaggttc gaaaactttt ttgggaaggt gtgcacggga
     3721 ttgatagatg aggtctatct ataaaaaatc acaaaatccg cgccattgct ggatccgcca
     3781 aaaatccccc accttacggc agacaaagaa aacgcgaatt atgggcctgt tgcagagaaa
     3841 aaaggtctca ctagttttgc gcatcctagc atcgaggttc gtcagcctcc catcagcaac
     3901 cagataacta atctcgctgg tgggcatgat gccgatatgg ggactcccat aacggtttat
     3961 ccgtgatcat ccaccagctt gatgacagat aacagggagt cataacggtt aaaattgtat
     4021 acttttacag caaacatttt tagctacacg ttaagctata cgattttgag tttaaatttt
     4081 ttaagctcaa ttaaatcaaa tggttatacg cacgttttga attctctcgt ggaccaaaaa
     4141 tcccaagaaa aaaccaaccc ttacggttgg tttttttata tctgcaatta attcgataaa
     4201 cagaccgtga cacatcacag cctgtttatt ttctgttatc agaacgtcca gaccacaccc
     4261 gcctgagtat tccacggcga ttctacccct gcgccattgc catagctgac tgacaaatga
     4321 ccgcttaacg tcggggtaaa cgatgacctt ataccagcct gataaacgcc actggttcca
     4381 gccacatcat tattaaattt gccatcgtca ttaactttca cctggttaga atcggcgtat
     4441 tcctgacgca cggccgcttt cagccagggt tccagcgtcg taccgttttg caggtccatg
     4501 tgatagctta ccgccgttcc cgcttcagcg cgtaatatcc gggtatttcc cacatccgcg
     4561 cgcatgccgt ttgataacgt gtagtcctga ccatctgtgg taaagccggt aaaggccaga
     4621 tagggtctaa cactccacaa tccgtcaacc caacggaacc cgctctcaac atgagcaccc
     4681 gcgccgttac tattgtaatc gccaaacgct gttgccccat tactcatctt gccatggatg
     4741 gtgttggcaa aacggtcaac tttcaccacc ccatcaacat aggcaccgtt ctgatgctcc
     4801 caaccggcat aagcccccag ggtatagcta tcgatattac ctttgccgcc gcgatcaaaa
     4861 ccaatatcag aatgagagta accaaagatc aagccgcgaa ttgtactgct ttcttcacgg
     4921 gagaaacggc tatcgatacc gagcgtcagg cccgtcaatg tttgctcaaa accagctccc
     4981 gcatcagtgg tcacgttgtt gcgggtgtta attgccgaac tccacatcgc cgtatcgtaa
     5041 ctaacgcctt ttacgctacc aagacgctca cgcacggtgt ccagttctgc atcaaatacc
     5101 agcggttgtg cggccgccat attcagcaca tcagtggttg aaggggtaat ttgcgcgcga
     5161 ttctctgcca gactccagct atggttgcca ttatccagca aggtatattc atacgtaccg
     5221 atatcaacaa cgcctccggc attgcccaac gtaaatgcag catcaccgcc gcccgttgtt
     5281 accagtgtaa ggctatctcc tgctgccggg ctggcaccgg tgtccgtcac gaatattttg
     5341 aaatcacctg ttgcctgacc ggtgacgttg agctgatcgc tctgatgatt agccatatcg
     5401 gtacgcatat aaaaattgcc gtttcccgac agggtattgg tggtcaacgt aatgaaattt
     5461 tccgcacttg ccgtcactga tgaacgagtc actggctcat ccatcataat cacatttgcg
     5521 tcagacatcg caaggttggc taagttgagg agggtgtttt ggttcgtcgt agtgatatcg
     5581 gcaatgatgg tccatacgct attttcgagc gaaacgtccg ctttgctggt atccacggca
     5641 ccatgcgttc taaaagaagc gccctcagaa accactacct tacccaccaa cattgcgggt
     5701 gcataattta tttgcggctt catgacctca agaatgccat cattccctct gactgaaacg
     5761 ttaaccattg tgccagccca gacgttagcg cggccattgt tgataaccat attttcagag
     5821 atggcttttg aggaatacgt gatacttcca ttctgatatg atcgaccgag atcatatacc
     5881 gcatttgcct gcactttcgt accagtatcc tttcccagcg attgcatagt ggcatgctta
     5941 tcaaggatag tatcaatggc ctgcgtgtcc tccataacaa tgagcccgga accatcatcc
     6001 agttcataat tttttgacac accatctttt atactaaatt ggcctttact gtttggacca
     6061 ctcacttcca gcgcattcgt tgagacaatt aattttccgc ctgctttttt atcaacgcca
     6121 gttacagtcc cgccatccat aacctccagt aagccgccac tatctacagt ggtattataa
     6181 gcgaagtcat tttcttcaac tcgcaaactt ccgccgtttt ccaacaacat attattagca
     6241 ataccattct tgatatcgaa ctgaccgaga cggtttgttc cgaatacctc catggcccgc
     6301 gtggttgttt taatagcacc gcctgctttc tgatctaccg caaatgcaaa tcccccctct
     6361 ttaacctcca gtagtcctcc cttttcgata gcgacaaaga cggccccccc atctttttca
     6421 acgattaagc gcccgccttt aatcgtggta tcattcgctg cgccataaac ctgtagcaca
     6481 ccattattga gcgtagtctg gtttgccgcg ccacccattt gaacaatttg ataaccgtca
     6541 tttaatactg agtattctgc ggcgccattc atttcaatgt actgataccc tccgttaatt
     6601 tcagtattat tacttacacc aaattctttt atatgctgtt ctccgccagg attgattttc
     6661 gtattattgg cggtcccata aaccagctgg atatcttttt ccaggacaac accatcaact
     6721 gtctcaccat actcaacagt tgatgccaat gctatgggtg aatataacgc tgtagccacc
     6781 agaacagata ttgcggaacg acaaagagaa acagaaccag attgatgcat tgagctttca
     6841 tcctatgaaa ttaattgctg ttaaaagcat tgggtacaga aaatacccat agctccatac
     6901 ccggagtcag tttttaaaaa ctgtttaaag aaatgcacaa gtattgtgat tgatttttta
     6961 gttgtttttc ttgatgagaa gctgatgcaa aattccgtct ttataatgaa aatgatgcca
     7021 aagcgaacga caaggttgta gttttcacta catgtccata cataaaatgg ggtaacattc
     7081 acgcgcctgg tagcgttacc aacgctacgc tcaaacataa tgattctaat aaaacctcag
     7141 gagactacta tgcctgaagc aacgcctttt caggtgatga ttgtggatga tcatccactt
     7201 atgcgacgcg gtgttcgtca gttactggag cttgatcctg gctttgaagt ggtcgccgaa
     7261 gcgggcgacg gcgcgagcgc tatcgatctg gcgaatagac tggatatcga cgtgatcttg
     7321 ctggatctca atatgaaagg tatgagtggc ctggatactc tcaatgcctt gcgcagggat
     7381 ggcgttaccg cgcaaattat tatcctgacc gtatccgatg cctccagcga tgtctttgcg
     7441 ctgatagacg caggcgcaga cggttatctg ttgaaagaca gcgacccgga agtattgctg
     7501 gaagcgattc gtgccggagc gaaaggcagc aaagtcttta gcgaacgcgt caatcagtac
     7561 ttacgtgaac gtgaaatgtt tggcgcggaa gaagatccct tcagcgtgct gacggagcgc
     7621 gagctggatg ttctgcacga gctggcacag gggctgtcaa ataaacagat tgcctcggtg
     7681 ttgaatattt ccgagcagac agtaaaagta catattcgca atctgctgcg taaactcaat
     7741 gtccgctcac gcgtggcggc caccattctg ttcctgcaac aacgcggggc acaataaaaa
     7801 tagcccgatg gatttatcat cgggctgaga tttatgacaa acgcaaaact gcctgatgcg
     7861 ctacgcttat caggcctacg tggatcgatc aatttattga atttacacaa ttttgtaggc
     7921 cggataaggc gttcacgccg catccggcat aaactaagcg cactttgtca acagtctagc
     7981 ccgatggcat caccatcggg cctcttttta tttactctcc tgcggcgaca aatgttgcat
     8041 cgcctgcgcg atactacgtt caatcaccgc acggcgagta tcgttggcag gtaagagttt
     8101 caacatcatc tcccacgcgg caacggcttc gccaaatcgc tgctgctcaa aggcattaaa
     8161 cgcatacatg cttagcacac ggatattgct atggtccgtt ctcaccagct gacgtagcag
     8221 ttcaccgccg aggcggttgt cgttgggatc agatgaacga gtcaacgctt cagcgtatcc
     8281 cagtgcagca tcactgtttt tcggatcgag gcgatacgca gtggcgtatg catcggtggc
     8341 gatactggcg ttacccagcg ccatgccaac gcggcccaac ataatccagc cttctatatc
     8401 tcccggattt ttttgcagtt gagtacgcat ccccagcgca agacgcgaca tctcttcttc
     8461 gttgagcgga tcggctttcg gatccagcgc cctgtccagc aacgccggag cctgtgccgt
     8521 ggcctgctgc cagattttca cctgctgata attgccagtc tggtagtagc tgacgccagc
     8581 cacaattaac gccaccacaa tacccggcag ataaacaaca tatccggcac gcttaccttc
     8641 cggcacgctt tgttcaggaa acgcttccgg caccacgcgt acccgacgcc gcgagcgggc
     8701 gtatatgacc caaccgccaa tgccaatagc cactactggc agcacccaca gcagcacggt
     8761 cagcggcgtt aacggcggat cgtaagtgac gaagttgccg taacgcgcca ccatataatc
     8821 gacaatctct tttttacttt taccttcctg catcagttca tacactttct gacgcaggtc
     8881 ggtggcaatc atcgagttgg aatcggcaat gctgttgttc tggcatttcg ggcagcgcag
     8941 ttcttcagtg agctgacgga actgttgttc ctgtgcttca tctttaaact gcaacacatc
     9001 gatggtcgcc agcgctgagc cggagatcat cagcatcagc acgcccaata aaaacctcat
     9061 tgtgcggcct ccttactgta tttctcccac agcggcttga tctcttcttc ccagacgcga
     9121 ggattcagat cgcccgcatg gcgatagcga atgatgccgt tgccgtcaat aagaaacgtt
     9181 tctggcgcgc catagacacc gagatccagc cctaacatgc catcgccatc aaacaggctt
     9241 agcgcgtaag gattgcccag ctctttcagc cagctgattg ccttctggcg atcgtcttta
     9301 tagttcatgc cgaccacgcg gatgccctgc gcagaaagct gattcagata ttgatgttcc
     9361 gcacggcagg tcggacacca ggtcgcccag acgttaagca gtactggttt gccctgagtc
     9421 agcacatccg cctgataaaa ctgccccgga ttgtccagtg attcgagacg aaacttcggc
     9481 acaggcttgc caatgagcgc cgattccaga ttggtcggat catccccttc ggcattacgc
     9541 gccagctgcc acagcagcgc cgcggcaatc gccaggaaga taatcaacgg aattaacaat
     9601 actttgcgct tcatacggcc tccggcgcag ttttttgcgg actcacgcgc ttacgatagc
     9661 gaggatcaaa cagacacagc agtccgccca acgccatcat cagcccgccc gcccaaatcc
     9721 agcgaacaaa tggtttgtag taaagacgca cggcccacgc gccgttttcc agctcttcac
     9781 cgagggccgc gtacaggtca cgcgtgatgc cgccgtcaat tgccgcttcg gtcatcatcg
     9841 acccggcagt gttgtaataa cgtttttccg catacagcac cgtttccggc ttgccatcgc
     9901 gcgttacgcc gatagtcgcc acaccgccac gccagttcgg gccagtcacc tctttgacat
     9961 cacggaaggt gaagcgatat tcatgaatat cgacgctatc gccggacttc atgcgcacat
    10021 cacgctcaac gctatagttc tggctaaagg caatgccaac aattgtcact gccagcccaa
    10081 ggtgagccgc caccatcccc caataactga aggtggtttt cgtgccgcgt gaaatacgta
    10141 gcgcagcttc cgcaattgcc agcaccgcaa tccagcaggc cattgccagg ccgagcaccg
    10201 tcatcgccac aactttgctt tcgaacagcc acggcaacag cagcgacagc accagcgtag
    10261 agatgaaggc gataatcaat aaattgcgga tcttacgcgg gcgatcccgc ccccagcgca
    10321 ccagaggacc gacaccaagc agtagcgcaa acggcaccat cagccaggta aacatggtgt
    10381 tgaagaacgg ttcgccaatc gaaatactgc ccagtcccag ttgcttatgc accaacggca
    10441 gcagcgtccc cagcaacacc accagcatcg cagcgaccag caaaacattg ttcgctaaca
    10501 gcaaagattc ccgcgaccac agcgcattgt ttacgcgtga gcgaactttg tgtccacgcg
    10561 cggcaaacag cagcagcgaa ccgccaatca ccagcaccat aaaggcgagg ataaacatac
    10621 cgcgcgccgg atcagacgca aacgcgtgta ccgataccag cacgccggaa cgcacgagga
    10681 aagtccccaa cagacacaac gagaaggcac tgattgccag cagtaatgtc cacgctttga
    10741 agctggcgcg ttgttcagtg accgccagtg agtgcatcag cgcagtcccc accagccacg
    10801 gcataaacga ggcgttttct accggatccc agaaccacca gccaccccag ccgagttcgt
    10861 aataggccca tgcggaaccg agcacgatgc cgagcgtcag gaagatccac gctgccagcg
    10921 tccacggacg agtaaaacgc gcataagtgc tgtccagacg cccgctcagc aaagaagcaa
    10981 tggcaaaagc aaacgccacc gagaaaccca cgtaccccat ataaagcaga ggcggatgga
    11041 agatcagccc cggatcctgc aatagcgggt taagatcgcg accttcaatc gggaagttcg
    11101 gcaacgtgcg agagaacggg ttagaggtaa agagaatgaa cagcaaaaag ccgacactga
    11161 ccatccccat tatcgccagt acacgggcca caatatccag cggaatacgc tgactaaaaa
    11221 tcgccaccgc aaaggtccag ccgctcatca gcagcaccca cagcagtagc gagccttcat
    11281 gcgcgcccca ggtagccgcc acgcgatacc acaccggaag ctgggtattg gagttgctgg
    11341 caacataggt gacggtgaag tcgttgacca cgaaagcatt gaccagcacc agaaatgcgc
    11401 cagccacaga cataaacagc agccaggcaa acaagcggga agacgccatc atgcgcgcat
    11461 ctccgcgcgc cacgccccat agcggataca cggacagcag cagcgcaatt cccagcgcca
    11521 ggcacagcag tccgttacca atttctggca tcatgatgct gggtccttat aaacactcgc
    11581 cgggcgacgg tggttagctt ccatcgcttt ctcaacttct ggcggcgtat agttttcatc
    11641 gtgtttcgcc agcacttctt tcgcgaggat atgattgcct ttttccagtt cgccctgcac
    11701 cacaacgccc tgcccttcac ggaacagatc cggcaaaatg ccttcgtaag agacatccac
    11761 tgagccttca gcatcgtaaa tggtgaaggt cactttcagc gaattgggat cgcgctgcac
    11821 actacccggc atcaccatcc cgccaacgcg cagacgctga ccgacttccg gcatttgctg
    11881 agtttcacgc ttgccgtaga gaatttcccc cggcgtataa aagagatcga tattcgagcg
    11941 cagcgcatat agcaccagac cgatagtcag cgccagccct gccaacacgg cacaggcaat
    12001 ccacaagcgg tttttacggc gaatattcat gcagcctcct gctgttgcgc agcacgtaaa
    12061 cgcgcctcac gcgcccgctg ttgcgccacg ccacgcagaa ttgcgcgatg ttgcatcacc
    12121 gagtgcacga ccaaaaccac cagcggaata acggtcatca ccaccgccag ccagacaaaa
    12181 aaggcgtaac cgcccattgc gaaaaattca ttccaggaag caaatgcagg ggtcatttac
    12241 ggcctctttt cagtatcagt tcactcaccc acggacggcg tttttccatc agcaaaatca
    12301 aattacgcat ccgcatcagc gtcagcgtgg cagacaggag caggaagcca aaaatcgacc
    12361 agcgcagcgg cgaacgcatc gccggatcga tactttgctg catccgcgtt gatccctgat
    12421 gcagggtgtt ccaccactcc acggagtaat gaataatcgg cagattcacc acgccaatca
    12481 gcaccaggat acctgccgca cggcccgcca gacggcggtc gtcgaaggcg tgccacaggg
    12541 caatcacacc cacatacaaa aacagcagca ccagttcaga agtcagacgt gcatcccata
    12601 cccaccaggt gccccacatc ggttttcccc atgcagagcc ggtaaccagg gcaataaagg
    12661 taaacacggc accaatgggg gccatcgccg ccaccgccag gttggccatt ttcatctgcc
    12721 agacaaggcc aataaacgct gccactgcca ttgatgcata aatgcccatc gaccagatcg
    12781 ccgcaggcac atgcaggtag ataatgcggt agctatttcc ctgctgataa tcagccggag
    12841 caaagccgaa tccccagatc cagccgacgg taagcacgac cacactggca attgccagcc
    12901 acggtataaa ccagccacag atttgataca gccgtggtgg gatcgccagt tgatgcagtg
    12961 ttttccacat agtttcgata ccagactcga acaaaaatca gtaatccagc gttattgaat
    13021 gctgattcgt aacgctgccg ccgtcgcaaa aggacttaat gtcgcggtgc ctgccagcaa
    13081 cgcgcctaaa attgccagat acccgtcaac gggcaaatgc atagaagccg cgtccatcgc
    13141 ggcggtggca aagatgagta atgggatagt cagcggtaac accagtatgc tgagcagcac
    13201 accaccgcgc ttaagtccca ctgtcagcgc cacgcccggt gcaccgagaa agccaagcgt
    13261 aggcgttccc agcagcagcg tcagcgccat cacttgccag ccataaacat ccattcccag
    13321 tagcattgct accagtggcg aaaggatgag taacggcaga ccggttacca tccagtgcgc
    13381 catcaccttc gccagcacaa cggcgggcaa gggtaacggc aacaacatca attgttcaag
    13441 actgccgtcc tgcaaatcgt cacggaacag tcgttccagc gccagcaagg atgaaagcag
    13501 cgcagcaacc cagataatgc ccggtgcaat acgcgccagc agttgcggct ccggaccgat
    13561 actgagcgga aaaagggtaa ttacaatcag gaagaaccac agcgggttgg cgatttcggc
    13621 gctatggcga aacgctacac gcagctcaag acggaaaatg cgccagaaca tcatgcggcc
    13681 ctcgtttgcg tcagtgaaat gcggcgaatt ttactttcag caacgttgag cggctggtgg
    13741 gtagtcagaa tcacaatccc cccctgctcc gtatgctgcg ccatacgctg ggtcagacga
    13801 tcgacaccgt taacgtcaat cgcggtaaaa ggctcgtcga ggatccataa cgtggcacgg
    13861 gtcagccaca gacgcgctaa agcgacgcgg cgttgttgcc cggccgagag ctgatttaca
    13921 ggaatatctt cgaatccggc aagcccggcc tgcgccaggg cttccagaca ttgtgcggta
    13981 tcgccatcgc gatgataaaa gtgcagattt tctaacgccg tcagccgggt tttgatcccc
    14041 ggctgatggc ctatccataa caggttttga tggtagctgt cgcgtacctg atgcaagggc
    14101 tgcccttgcc agagaacctc gcctgcgtca gggcgagaca accccgtcag caaacggaga
    14161 agcgttgtct tccccgcgcc gttgctaccg gtgatttgta cccactctcc tgcgttcagc
    14221 gtaaatgaca agccactaaa taaggttcgt tcatcccgct cacaaagtaa ctctctggct
    14281 tcaagcatac ccacgcaata accctgttaa aaacctggct cgacttcacg catatcgggc
    14341 agcttgtgcg ctatcccttt atggcaatca atacaggttt gcccatcttt caccgcctgg
    14401 tcatgcatct tcgcggcaac cgatttctgg gcggttgtat ccatatactc gaagttgtga
    14461 cagttacggc actcctgcga gttattgtcc ttcatgcgcc gccactcatt ctgtgccatc
    14521 gtcagacgat gagcttcaaa tttctgcggc gtgtcaataa cgccaaaaat tttaccatac
    14581 agctctttac ttgctttgag cttgcgtatc atcttcggca caaactcgtg cggaacgtga
    14641 caatccggac aggtcgcacg gacgccgcta cggttgttgt agtgcacgga atccatgtat
    14701 tcctgataca ccgtgttgcg catttcgtgg cagctaatgc agaactcttc ggtattggct
    14761 ttttccatcc cggtgttaaa gccaccccag aagacgatgc cgccaacaaa accgatcaac
    14821 agcagcgtcc ccagcgccag acggctgggg gtacgccacc atttccacag gcgcttaatc
    14881 agaccaggct tacggtcaga atttcccata ataacctctt atttcccgta accttttgat
    14941 ggggtaaagg tattccccac gattggcgcg gtatcggcct gcggtacgtg acattgcaga
    15001 cagaaataac gacgcggagc cacttccgcg cccactttgc cgtcgctgtc cataaagtga
    15061 gtaggactga tacgcggcgc gccagtggtg cgatagcttt cgacaccgtg gcactgcaag
    15121 cagcgattgg tattggtcgt tacctgataa ccttcaacgc tatgcgggat cattggcggc
    15181 tgattcacat agttcagcgg catccgatcc tgctcttttg gcatccgaat ggccccttcc
    15241 tgtgtcccgg atacttccgg cgactggcta aaatcgacgc cattagccgc ccaaaccgcg
    15301 ccgcttacca ccagggccag catcgccgtc cattgacaca gcgctttctt caggtcatgg
    15361 cttttcatga tttcgctccc gaactccatc gtgtagttat tgtaaataca tcctcagaac
    15421 agacatccac gcagcgaccg cacgtcatgc aatcgcggct ggtgacctgc accgggcttt
    15481 gttcatccag caccggggca cgtagcacat gcggttccgg gcaaacatga aaacaatcca
    15541 tacagcggtt acatttctgc cgatcggtgg ccgcaacggt aatcacacct ttgctaccca
    15601 gcacgccata cagcgcgcca accggacaaa tgtgcccgca ccagccgtgt tcaacgacca
    15661 gtagatcaaa taaaaacagc gcgagaataa gcagcgcgcc gctgccgaag cccattacca
    15721 ggctacgccc catcagagaa acggggttga tccattccca aatgagcgtg ccagttaagg
    15781 ctgatcccac cagaatgacc accaacagca cgtagcgaat gtggcgaggg atcgtcgcag
    15841 actgattgag gtcaaagcgc ctgcgtaacc agttcgctaa gtcggtaatc gggttcagcg
    15901 ggcagaccca gctgcaaaat aatcgctttc ccgccagggc gtagagcacg gtgataatca
    15961 ccgcaccggt caacgccacc gtggcaggca gatgaccact ggcaagactt tgcagcgtca
    16021 tcagcggatc ggtcagcgga acggtgtcga ataacaggct actgctgtag ttgccgtgca
    16081 agatccacac accaaaccat ggaccgctca aaaacatccc cagcacgaag aactgacaaa
    16141 ggcgacgtaa caccagccaa cggtgactgc gccaccagcc ttttttctcc agcgcctcgc
    16201 gcccggcgtc acgtttacga tttgccattg ttcccctcca gccagccgaa gcggtaatgg
    16261 tgacctaact cccctttcgc cagtgacagc ggtaacacct tgattgccgg ttgttccagc
    16321 acgcatactt tttcgcactt accgcaaccg gtacaggcgt cgctgtgaac cgtcggcaga
    16381 aagcgggcgt gcttaccggt acgcgtgttg cgctccagct ccagggtgat ggcctcatca
    16441 attttcgggc attcgcgata acaaacatcg cagcgcagcc cctgaaagtt gagacagttt
    16501 tcctggtcca ccagtaccgc cagccccatc cgcgcgtcgt cgatcgattc aatctcacga
    16561 tccagcgcac cgcttgggca cactttggcg cacggaatgt cctcacacat ttcgcaagga
    16621 atatcccgtg cgacaaaata tggcgtgccc gccgacagac cagaggccag cgtcgccagt
    16681 tttaaggtgt cgtaagggca agcctgaaca cactgaccgc aacgcacaca ggcactggca
    16741 aaggcgttct cgtttatggc tccgggcggg cgcaaccgca cgccagatgc gcgtgcggtt
    16801 tgctgttgta accccagcgc cacacccacg gcagccagcc cgcctgctgt gcgaacgaca
    16861 tcgcgcagaa agcggcggcg accattttga ggtttcgctg accgggacat aatggcttac
    16921 accttctcca gtttgaccgc gcacttcttg aagtccgtct ctttcgagag cggatcggtc
    16981 gcatccagcg tcagtttgtt aaccaactgt gcggcgtcga agaacggcat gtacaccagg
    17041 ccctgtggcg gacggttacg accgcgcgtt tcaacaatcg agatcacttc gccacggcga
    17101 gaaaccactt tcactttgtc gccacggcgc agatcgcgcg ctttcgcatc cagcgggtga
    17161 ataaacagga ccgcttccgg gaaggcgcgg tgcagttctg gtacacggcg agtcatactg
    17221 ccggtgtgcc agtgctccag aacgcgtccg gtagagagcc acaggtcgta ctcttcatcc
    17281 ggtgcttccg ccgccggttc gaatggcagt gcgaagatca ccgctttgcc atccggttta
    17341 ccgtagaact tatagccttc gcccgctttc acgtacgggt cgttaccttc gctgtaacgc
    17401 cactgcgttt ctttaccgtt caccaccggc cagcgcagac cgcgcgcttt gtggtagtca
    17461 tcgaacggtg ccagatcgtg accgtgaccg cgaccaaacc atgcgtactc ttcgaacagc
    17521 cctttttgca gatagaagcc cagctcgcgg gattcatcgt tcagctgatc ttccgccagt
    17581 tcggataccg ggaatttgct cacttccggt gtggcataca gcacttcgta cagcgttttg
    17641 ccacgcagtt ccggtttctt cgccagcaga tcttccggcc atacttcttc agttttgaag
    17701 cggcgggaga actggactaa ctgccagaga tccgatttcg cttcgcccgg tgcctgtacc
    17761 tgttgacgcc agaactgagt acggcgttcg gcgttaccgt aagcgccctc tttctctacc
    17821 cacattgcgg tcggcaggat caagtcggcg gccagcgcac tgactgtcgg atacggatcg
    17881 gagacgatga tgaagttgcg cggatcgcgc cagcccggca tacgctcttc attgatgttc
    17941 ggcccggcct gcatgttgtt ggtacacatg gtccagtaaa cattcagttt gccgtctttc
    18001 agcgcacggt cttgtgccac cgcgtgcaga ccgattttcg ccggaatggt gccgctcggg
    18061 atattccact tcttctcgca gatatcacgg tgtttctcgt tggtcaccac catgtccgca
    18121 ggcagacggt gagcaaaggt gcccacttca cgcgcagtac cacacgcaga aggttgcccg
    18181 gtcagggaga acggaccgca acccggctgg gaaattttgc cggtcagcag gtgcaggttg
    18241 tagaccaggt tgttagccca cacgccacga gtatgctggt tgaagcccat cgtccagtag
    18301 gagatgactt tcttgttcgg atcggcatac agctgcgcca gttgttctaa ctggtctttc
    18361 ggcacgccgg tcatttcggc agttttttcc agcgtatact cggcaacgaa ggctttgtaa
    18421 tcttcaaagc tcatcggttc ggaggcgtca gaacccggat tcttcgctgc tttttccagc
    18481 ggatgggtcg gacgtaaacc gtagccgatg tccgtcgccc ctttgcgcag gttaacgtgc
    18541 ttgctgaaga agtcctgatt tatcgcattg ttttgaatga tatagttggc gatgtagttc
    18601 aggatcacca ggtcagattg cggcgtaaag atgatgccgt tatccgccag ttcgaagcta
    18661 cgatgctggt aggtagaaag caccgccacg gtgacgttct ggttagagag acgacggtta
    18721 gtgatgcgcg accagaggat cgggtgcatt tccgccatgt ttgcgcccca cagcacaaac
    18781 gcgtcagcct gctcgatgtc gtcatagcag cccatcggct catccatacc aaaggtacgc
    18841 ataaagccaa ctactgccga cgccatacag tgacgcgcgt tcgggtcgat gttgttcgaa
    18901 cggaagcccg ctttaaacag cttggacgcg gcataacctt cccagatagt ccactgacca
    18961 gaaccgaaca taccgatcga ttccggccct ttttctttca gggcggtttt gaatttctct
    19021 tccatcacat cgaaggcctg atcccaggtg attggggtaa attcgccttc tttgtcatat
    19081 ttaccgtttt tcatacgcag cagcggctgc gtcaaacggt ctttaccgta catgattttg
    19141 ggcaggaaat agcccttaat gcagttcagg ccacggttaa ccggtgcgtc cgggtcgccc
    19201 tgacaggcca ccacacgtcc ctgctgcgtt ccgaccagaa cgccgcaacc agtaccgcag
    19261 aaacggcacg gcgctttatc ccatttgatg gcttcctgct gaccaacaac ggcgcgggca
    19321 acgcccggca cgctgagacc ggcagccgcc gcagcggccg caacggcgtt agctttcata
    19381 aagctacgac gactgagttt catggtgttt cctcaccttg ctcttcctgc tggtgataaa
    19441 ccagcgacac cgccagcacg ccctctacgt tgcgtactga ctcaatggtt tggatcagcg
    19501 tttcgctgtc ttctgcttcc accaccacaa tcaactgacc gctcggcgcg tcgctgacag
    19561 caacttcaca gccgggaaag gcgttcagtt gggtgctgat gtctgaaatt cgttcgcttt
    19621 tggcctgcac gaccaggctg caaacttgcc agttagtgtg catggagata ctccgcagtt
    19681 atggctgata ccggacagct ggctgcacat gctccacatc cgttgcaaag ttggctatta
    19741 agttgcggct ggtagatccc ggagagcgtc gggcgaaaga taattgccat tggctcacag
    19801 ctatcctgac agcggcggca ttcaactgac tgatacgcca ggcacgcgtc cccgatggtg
    19861 aactgcaaat cccaggccct ggtgtggcgc ggagaaaata gcgattcggg gcaagcctgc
    19921 gcgcagtcgt aacagaagct gcactcgtta tttttgaaat taacgctcgg atagccgccc
    19981 gcgccgcgtt gcagaatgtt gttttcacaa gcattaatac aggcgtcgca gcgggtgcaa
    20041 tgggtcagaa aatgagattc atcaccggac cagggcggac ggataccgtt actggctttg
    20101 cgccagcgac cagtgagtat gccccgacgg gatgcatcaa tcttcacatt gaccttccat
    20161 cattaacgcg ctctgaaaat tgagagcgac caaataaacc gcataattaa taagccattt
    20221 ttatagccgc taagatatta aaggatgtgt caaagatgca taccccgatc ggggtaaaac
    20281 ctgtagcagg atcaaaagag tggcgggaag cgtggcaaaa acgggctttt gctca
//
LOCUS       DAPHKZ010000079        20185 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.079, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000079 DAPHKZ010000000
VERSION     DAPHKZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20185
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.079"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(32..790)
                     /gene="aroD"
                     /locus_tag="RH288_002997"
     CDS             complement(32..790)
                     /gene="aroD"
                     /locus_tag="RH288_002997"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDV4032036.1"
                     /translation="MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDI
                     LEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNR
                     AAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
                     MQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEV
                     FGSAATFGAVKKASAPGQISVNDLRTVLTILHQA"
     gene            complement(821..1687)
                     /gene="ydiB"
                     /locus_tag="RH288_002998"
     CDS             complement(821..1687)
                     /gene="ydiB"
                     /locus_tag="RH288_002998"
                     /EC_number="1.1.1.282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinate/shikimate dehydrogenase"
                     /protein_id="HDV4032037.1"
                     /translation="MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEV
                     DNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLR
                     GYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEF
                     FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVN
                     DISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFP
                     LEYVKQVMGFGA"
     gene            complement(1699..2964)
                     /locus_tag="RH288_002999"
     CDS             complement(1699..2964)
                     /locus_tag="RH288_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416206.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4032038.1"
                     /translation="MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMSSLAEKFS
                     TDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMYLLFFFGIPACPNLT
                     LAYCLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
                     LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVANELPQMNSKPLVWLEGVSS
                     VLFGVAAFSTFYVIVVWMPKYAMAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKM
                     VRPIWANVFNSALATITAAIIYLYPSPLVCNAGAFVIGFSAAGGILQLGVSVMSEFFP
                     KSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRY
                     YRVFIIPENDVRFGERKFCTRLNTIKHRG"
     gene            complement(3191..4405)
                     /locus_tag="RH288_003000"
     CDS             complement(3191..4405)
                     /locus_tag="RH288_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4032039.1"
                     /translation="MKNPYFPTALGLYFNYLVHGMGVILMSLNMASLETLWQTNAAGV
                     SIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILHTNNIIIAYGLG
                     FLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
                     GWSFMIAAGIMFINALFLYRCTFPPHPGRRLPVIKKTTSSTEHRCSIIDLASYTLYGY
                     ISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTT
                     LLMLYTFISFIALFAVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGK
                     ATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFLLALFIGLRSRKETW
                     HHSLKENVAPGG"
     gene            complement(4505..4861)
                     /locus_tag="RH288_003001"
     CDS             complement(4505..4861)
                     /locus_tag="RH288_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416204.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiL family protein"
                     /protein_id="HDV4032040.1"
                     /translation="MNAYELQALRHIFAMTIDECATWIAQTGDSESWRQWENGKCAIP
                     DRVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQRVYPDGNFIDWKIY
                     QSVAAELYAHDLERLC"
     gene            complement(4997..5104)
                     /gene="rprA"
                     /locus_tag="RH288_003002"
     ncRNA           complement(4997..5104)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="RH288_003002"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(5290..6402)
                     /gene="ydiK"
                     /locus_tag="RH288_003003"
     CDS             complement(5290..6402)
                     /gene="ydiK"
                     /locus_tag="RH288_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HDV4032041.1"
                     /translation="MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTV
                     VIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISS
                     GDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
                     GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLL
                     AVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKPNK"
     gene            6791..9847
                     /locus_tag="RH288_003004"
     CDS             6791..9847
                     /locus_tag="RH288_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDV4032042.1"
                     /translation="MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGVRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVY
                     QRCRQQRQLIIDNFPKLNRFLTGYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARL
                     DITRLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDQEMLGLNIVEFAGDDEALIDERVNALCARLDELIASHQAGVIGWQVCREL
                     AGVERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQEILMKQISDDVVALTAKYGGLLWGEHGKGFRAEY
                     SPAFFGEELFAELRKVKAAFDPHNRLNPGKICPPEGLDAPMMKVDAVKRGTFDRQIPI
                     AVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEQELPESGVSLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYAPLMARAPKTFNFFINQPLVR
                     KLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLESLNAEQKARTVLVVQDPFTS
                     YYDAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAK
                     LGMPMVGVDPALVLCYRDEYKLALGEERGEFNVLLANEWLASALESQPVATVSGESWY
                     FFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHEAKNHENSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK"
     gene            9844..10254
                     /gene="menI"
                     /locus_tag="RH288_003005"
     CDS             9844..10254
                     /gene="menI"
                     /locus_tag="RH288_003005"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HDV4032043.1"
                     /translation="MIWKRKITLEALNAMGEGNMVGFLDIRFEHIGDDTLEATMPVDS
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSAREGRVRGVC
                     KPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL"
     gene            10354..10542
                     /locus_tag="RH288_003006"
     CDS             10354..10542
                     /locus_tag="RH288_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HDV4032044.1"
                     /translation="MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTL
                     SSAELKEEIYFAWRLGVH"
     gene            11090..11458
                     /gene="sufA"
                     /locus_tag="RH288_003007"
     CDS             11090..11458
                     /gene="sufA"
                     /locus_tag="RH288_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HDV4032045.1"
                     /translation="MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLG
                     VKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQI
                     FKFHNPKAQNECGCGESFGV"
     gene            11467..12954
                     /gene="sufB"
                     /locus_tag="RH288_003008"
     CDS             11467..12954
                     /gene="sufB"
                     /locus_tag="RH288_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416198.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDV4032046.1"
                     /translation="MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVR
                     AISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDT
                     CASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKN
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            12964..13710
                     /gene="sufC"
                     /locus_tag="RH288_003009"
     CDS             12964..13710
                     /gene="sufC"
                     /locus_tag="RH288_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDV4032047.1"
                     /translation="MLSIKDLHVSVEDKAILRGLSLDVHPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTGGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVKSGDFTLVKQLEEQGYGWLTEQQ"
     gene            13685..14956
                     /gene="sufD"
                     /locus_tag="RH288_003010"
     CDS             13685..14956
                     /gene="sufD"
                     /locus_tag="RH288_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDV4032048.1"
                     /translation="MAGLPNSSNALQQWHHLFEAEGTKRSPQAQQHLQQLLRTGLPTR
                     KHENWKYTPLEGLINSQFVSIAGEISPQQRDALALTLDSVRLVFVDGRYVPALSDATE
                     GSGYEVSINDDRQGLPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPAKPLLLMHITQG
                     VAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKL
                     AFENPLSHHFAHNDLLLAEDATAFSHSFLLGGAVLRHNTSTQLNGENSTLRINSLAMP
                     VKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNN
                     LLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQIFYLRSRGINQQDAQQMIIYA
                     FAAELTEALRDEGLKQQVLARIGQRLPGGAR"
     gene            14953..16173
                     /gene="sufS"
                     /locus_tag="RH288_003011"
     CDS             14953..16173
                     /gene="sufS"
                     /locus_tag="RH288_003011"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HDV4032049.1"
                     /translation="MIFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEA
                     EFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVA
                     NSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTL
                     FDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCD
                     FYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEA
                     GTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVD
                     RLVTGLQRIHRLLG"
     gene            16186..16602
                     /gene="sufE"
                     /locus_tag="RH288_003012"
     CDS             16186..16602
                     /gene="sufE"
                     /locus_tag="RH288_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HDV4032050.1"
                     /translation="MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSP
                     QNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS"
     gene            16751..17755
                     /gene="ldtE"
                     /locus_tag="RH288_003013"
     CDS             16751..17755
                     /gene="ldtE"
                     /locus_tag="RH288_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtE"
                     /protein_id="HDV4032051.1"
                     /translation="MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTV
                     QEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNL
                     AELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
                     GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIK
                     ALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQ
                     FKDNKAVDQKLVDKALYRRAGYPVSVSSGATPAASNAPSVESAQNGEPEQGNMLRVTQ
                     "
     gene            complement(17819..18055)
                     /gene="lpp"
                     /locus_tag="RH288_003014"
     CDS             complement(17819..18055)
                     /gene="lpp"
                     /locus_tag="RH288_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein lipoprotein Lpp"
                     /protein_id="HDV4032052.1"
                     /translation="MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK"
     gene            complement(18366..19778)
                     /gene="pykF"
                     /locus_tag="RH288_003015"
     CDS             complement(18366..19778)
                     /gene="pykF"
                     /locus_tag="RH288_003015"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HDV4032053.1"
                     /translation="MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGN
                     SEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVV
                     MVSGALVPSGTTNTASVHVL"
BASE COUNT         5274 a         4850 c         5175 g         4886 t
ORIGIN      
        1 ggggagggtg ttcccgccga aatattattg cttatgcctg gtgtaaaata gttaataccg
       61 tgcgcaaatc atttaccgag atttgccctg gcgcagacgc tttttttacc gcaccaaaag
      121 ttgccgccga gccaaatact tcaccagcca gacgagaaat tacgccagtt tttgccatcg
      181 acatcgtgat aattggacga tcggcatact gctcctgcat ctccagggtc gcggcaagca
      241 acgtcagcac atcgctggta ctttgcggca tcagcgcaat cttaggaata tcggcgtcga
      301 aggattgcat tttgcgcaga cgggcaatga tttcttcggc ttccggcgtt ttatggaagt
      361 catggttgga catgactact ttcacatcat gcgcgtgggc gtaggcgacg gtttctttaa
      421 cctgatcatc accggtaaat aactccagat cgatcatatc aaccaggccg ctgtcgatgg
      481 ctgcacgatt gagtgcaata taagcctcgg tggaaatcgc ctgctcgccg ccttctttgg
      541 cactgcggaa ggtaaacagc agcggttttt ctggcatggt ctcacggaga atttttgctg
      601 ccgccatgac agactccaca ttggagaggt cggcatagtg gtccacacgc cattccagaa
      661 tatcaaagtc cgcttcacga taggcgagag cttcggattt cacgctggcg atatctttcg
      721 ccatcagcga gacgatgatt ttaggtgcgc ccgtaccaat gacgagatct tttacagtta
      781 cggttttcat tttttaccct ttctgcacgc ggtcagcctg tcaggcaccg aaccccatga
      841 cctgtttaac atattccaga gggaaatctt tgccagtcca taatgtgaac tgttcagccc
      901 cttgccacaa caacatgccg tatccatcaa tcgttttgca accagcttgt tgcgcctgct
      961 gcaataactt cgtcatatgc gggttataca cgcattcagt gaccagaagt cccggatgta
     1021 acagactgat atcattaacc aatgattcat tctcaagggg tttcataccc acttttgtgc
     1081 cattggttaa aatgtcggcg gaagccaggg cttcagcaaa ggcttgctga tcggcgagat
     1141 cggtgaccgt gacgacacaa tcggtgtttt cattaacccg ctgcgcgaag gcgagggctt
     1201 tatcgaagaa ctcatcccga cggttaaaga gtttaatttc ttttaaacct tcaattgccc
     1261 cctgcgcgcc aattgccgtt gaggcaccac cggcccctaa cagcaccatc gttttgcctt
     1321 tgatatcaaa accgctctct ttaatggcgc gaatatggcc cgtgccgtcg gtgttatagc
     1381 cacgcagata gccatcatca ttaacgatgg tgttgatggc ccccaccagt ttggcagctg
     1441 gtgttaattc atcaacatat tcacacgcca gttgtttgtt cggcatcgat acaccagttc
     1501 cgcgcatttt gagggctttt aatccttcaa ttgctccagg aaagctatcg ttatccactt
     1561 cgaaggccat ataggtaaat ggcaatcccg ctttttctaa ggctttattc tgcatttcgg
     1621 gcgataaact gtggcggata ggataggcca tcaacccaat caattcgtat tttgcggtaa
     1681 catccataat taactccttt aacctctatg cttaattgtg tttaaccggg tgcaaaattt
     1741 acgctcgcca aaccgcacat cattttcagg aataatgaaa acgcggtaat agcggataaa
     1801 aacaataatt gcggtaatca gggccagcag cgcgaaagta aaatcgagaa caatgatata
     1861 ttgcaggccg atgttcgaca gataaccggt aatcagtgga ataacaaagt tagccagtcc
     1921 acccatcatc atataaatac tggtgacttt ggctttgctt ttgggaaaaa actctgacat
     1981 gaccgaaacg ccgagctgta aaatgccgcc agctgctgag aaaccgataa caaaggctcc
     2041 ggcattgcac accagtggag aagggtacag gtagataatg gctgctgtta ttgttgctag
     2101 tgcagagtta aatacattag cccagatggg ccggaccatt tttttcagta gtgcggcaaa
     2161 aataaagaca cagactaatg agcccatact gtaataagag atggttttta atgcctcagc
     2221 ttctgacata ccagcaaaag ccatcgcata tttgggcatc cataccacaa tcacataaaa
     2281 ggtcgagaat gcggctacac cgaacagtac cgatgaaaca ccttccagcc agactaacgg
     2341 tttgctgttc atttgcggta attcattagc tacgctggcg tccaccaact ggctggggaa
     2401 tttgcttttc aacagcatca acgtgatcag tacaaatagg atgcctggaa taatcagccc
     2461 atagccgtac cagatgttat tgagcaacat atagctcacc agcattgggt agaacatttg
     2521 tccgaatgac accatcgctt taaccagtat gaccgccgaa ccagaggctt tcggaaagca
     2581 ttccatgagc gcagggtagc cacccgtatc cagcgctgag ttagcgatac ctacgcacac
     2641 tgccagacag taggcgagag ttaaattcgg gcaagcggga ataccaaaga agaatagcag
     2701 atacattatt actgccatta atatcaccgc ccgacgacca aacttatcgg agatcacacc
     2761 gaagaataaa atactgatca atcgccccaa accgataccg gaaattaaat aggcaatgcc
     2821 cgcgttgtca gtggaaaact tttccgccag agatgacata ttttgggcaa gcgtaataac
     2881 actaatgccg tgcaggaaat agctgaagta aatacaaaga acagccagga taaatggcgt
     2941 gctgaaagcc ttattttgag acattttcac agctccttgc tgaaagataa tttcgttacc
     3001 gtacgtattg ttctccgacg gtttacataa ttactatact gaagatgatt ttccctgggt
     3061 acatggcata aagtttatgt ttccaggaat attgcatgtc atagtttgtt tttgatcgcg
     3121 attttcctta gtcagcgcag aaagagttat ttatccgtaa gatcttgcat gacctgaaaa
     3181 gaatattgca ttacccaccc ggagcgacat tttcctttag cgagtgatgc cacgtttctt
     3241 tgcggctgcg taagccgata aacagtgcca gtaaaaagcc gatggcagcg atggcggtat
     3301 cgaaccacat aatatcggca atacttcttt gggacagatg agccgtaatc aacggaatag
     3361 taaaggtcgc aatactgccc gcactgtaat agatccctgt agctttacct ttagcgtagg
     3421 ggaaacgttc agccattaat gtcaggccaa tttgcacaac acctccagca gaggtaaaac
     3481 caatgacaaa agcaaatatt atcaccacat aaaatgtggg atgcagacag acggcaaaca
     3541 gagcaataaa tgagataaag gtgtacagca tcagtaatgt tgttgggcga acggtattac
     3601 gaatgagtgg agcggtgata aatacacaaa gcagcgaacc cacggtgtag atactgagta
     3661 gtttgatcga catagtgtat gacatgcctg caacaaattg tccgtactgt gccagccact
     3721 ggctaaccag ataaaaggtt gccattgaga tataaccata taaggtataa ctggctaaat
     3781 cgattattga gcagcgatgt tccgtagagc tggtggtttt ctttatgaca ggtaagcgac
     3841 gacccggatg gggtgggaac gtacaacggt ataaaaacag agcgttaata aacataatgc
     3901 ctgcagcaat cataaaggac cagccgaacc acagttcagc ccacactaac aggctgatga
     3961 ttagcggtaa taaaaattgc ccgctggaaa caaatgcttt aattaaaata ttggctgtac
     4021 ccggtgagcg tggaaaagct tccatcaaac tgggataggt gcctgcatcg agaaaactgt
     4081 ttgccattcc cgccagaaag cccaaaccat aagcgataat gatgttattg gtgtgcagga
     4141 tgccaaaaaa gaaggccata tagcagcaca ttccgagcat gataaaaggg cggcgaccaa
     4201 agcgatcgga taataatcct gcaaaaagca agacacttaa tcgaccaata cccagcgatg
     4261 agataactat tgagacgcct gcggcattag tctgccaaag cgtctccagc gaggccatat
     4321 tcaggctcat caaaatgacg cccataccat gcaccaggta attaaaatac aacccaagtg
     4381 cggtagggaa atagggattt ttcataggtt ctacttagca aaggtgcttt aaaaagtgaa
     4441 gcgatgttgt gtcagcatcc gttcattatt gttgtaacaa cgacaattcc tttctgtgga
     4501 aaaattaaca aagccgctcc agatcgtgtg catataattc agcagctacc gattgataga
     4561 tcttccagtc aataaaattg ccatcagggt agactcgttg aaatgcggtt aagtcgggga
     4621 aaaaacgcat ggtgttgttg ccgatgcggt tatttatttt ctctatgatg gcatgaagat
     4681 gtttttttct ttgctgacgc atagccaaca gttgctcgac tacacgatca ggaatggcac
     4741 acttgccatt ttcccactga cgccagcttt cactgtcacc ggtctgggca atccaggtcg
     4801 cgcattcatc aatagtcatg gcaaaaatat ggcggagtgc ctggagttca taagcgttca
     4861 tcgtgtaatg gctgcatgaa ataaacaata aaatataaat aacattatca gcctgctgac
     4921 ggcttgaaga gagtcacagt atcttgtgca acattattgg aaagagtgag gggcgaggta
     4981 gcgaagcgga aaaatgttaa aaaaaagccc atcgtgggag atgggcaaag actacacaca
     5041 gcaattcgtt gtttcactca ggggatttcc atgcttataa atcaatatgt tgatttataa
     5101 ccgtgagcta atagtaggca tacggacttt ttgcgtcgat cagattcgtc tcattagttt
     5161 aaaaactgta aagaatttgc gacaggtact accagctgaa tggcggtaag caggaaaata
     5221 tggggaagag caagcaaata tcaattagcg gtggttaaca atcaggcggc agagccgcct
     5281 gatgagaaat tacttattcg gtttctcgat ttcgccaagt tcttcgagaa tttcttccgg
     5341 ttggtccgtc ggcggcggga cttcttccac ccacgcggca aacagacgcc aggaaacggc
     5401 taacagaacc ggaccaataa acagaccgat catcccgaaa gcaatcaaac caccaataac
     5461 gccagagaga atcaggatca gcggtaaatc ggcacccatg cgaattaaca ttgggcggat
     5521 gacgttatcc agcgtgccaa ccacaccgct ccacactaac aataccgttc cccaggtggt
     5581 atcgccagtc cagtagagcc agataatcgc cggaatcagt accggcaacg ggccaagctg
     5641 gacaaggcag gagaggatca ttaacaccgt tagcaacgtt gcataaggta cgccggatac
     5701 ggcgaggccg ataccgccaa gcactgcctg tactaacgcc gtcaccacca cacccagcgc
     5761 caccgcgcgg atagcctgtg ccgccagcag cacggcggca tctccgcgaa cgcctgccag
     5821 acgggttgca aaatggcgaa tgccttgtgc cacctgttca ccgcgccagt acagcagggc
     5881 actgaagaga agcatcagcg cacaatgcac cataaagcgc ccgatatgcg ccgcctgccc
     5941 aacgaaccag gtggtggtgg tgccaatata agggcggact ttcgccatga tcgccgtccc
     6001 ccccatatcc agcaagttgt gccagcctgc atacagcttc gcgccaatca ccggaatggt
     6061 attaagccac gccagatcgg gtaacgtcat gtcaccgctg gaaatggctt taattagcgg
     6121 gccgctgccg tcgacgatac tgttaaccag caaagcaata gggatgataa acaccatcac
     6181 taataacagc gtcatcacca gaacggcgag agagcggcgg ccaaacatga tcttttgcaa
     6241 acgtaacaat accggccagg tggcgataac caccgtaccg gcccatgcaa agccgagaat
     6301 aaagggttga acaatccaca gacatgccac aatcatgatg gctaaaaaca gcaccgaaag
     6361 cagaatttgt gcgacatccc tgggctgacg aacatttacc ataactactt ttcacctttt
     6421 ttgtgcgtca aatcgtcgac gcgacgtgaa cacgcgaaac tcacctgcat aatgatgagc
     6481 aatttcagcg gtttttaaca ggccgattct gcccttaatt ctgatgggcg tgttagaaaa
     6541 aaatgtggta caacaactca ggcaacacgc aaacgattta ctcgtcgtat ttcaagttgc
     6601 atgtgctgcg gctacgttcg ttcaccccag tcacttacta ttgtaagctc ctggagttca
     6661 ctcgcttgcc gccttcctgc aacacgaaat ccatagagta aacaaacatc acctttcagt
     6721 gcgctattgc agcagcctga aagaatagtg tatcgaccta catcacagac cgcaggaaag
     6781 ggtcaatata atgattccac agatttccca ggcacccggc gtcgttcaac tggtgcttaa
     6841 ttttttgcaa gagctggagc aacaaggttt taccggcgat acggcgacaa gttatgccga
     6901 tcgtctgaca atgtcgaccg acaacagtat ttaccaactt ctccccgatg cggtggtatt
     6961 tccgcgttca accgcagatg tggcgctgat cgcccgtctt gccgcgcagg aacgctattc
     7021 atcgctgatc tttacccccc gcggcggcgg caccggcact aacggtcagg cgctcaacca
     7081 ggggattatt gttgatatgt cccgccatat gaaccgcatc atcgaaatta accctgaaga
     7141 gggctgggtg cgcgttgagg ccggggtgat aaaagatcaa ctcaatcagt acctgaaacc
     7201 gttcggctac ttttttgcgc cggaactttc gaccagcaac cgggcaacgc tcggtgggat
     7261 gatcaatacc gatgcatccg gtcagggatc gctggtctat ggcaaaacgt cagatcacgt
     7321 acttggcgta cgcgcggtgt tgttgggggg cgatattctc gatacgcaac ctttacccgt
     7381 cgaattggcg gaaacgctgg gtaaatccaa taccacaatc gggcgaattt ataacacggt
     7441 ttatcaacgt tgccgtcagc aacgccagtt aattatcgac aacttcccca aacttaaccg
     7501 ctttcttacc ggttacgatc tgcgtcatgt ctttaacgat gagatgaccg agttcgacct
     7561 gacgcgcatt ctgacgggtt cagaagggac gctggccttt attaccgaag cgcggctgga
     7621 tattacacgc ttgcctaaag tgcgccgtct ggtgaacgtc aaatatgact cttttgactc
     7681 tgcgctgcgt aacgcgccgt ttatggttga ggcgcgggcg ctttcggtag agacggtgga
     7741 ctcaaaagtg ctgaatctgg cgcgggaaga tattgtctgg cattccgtca gcgagttgat
     7801 taccgatgtg cctgaccaag agatgctcgg gctgaacatt gtggaatttg ctggtgatga
     7861 tgaggcgctg attgatgagc gggtaaatgc actctgtgcg cggttggatg agctgatcgc
     7921 cagtcatcaa gcaggtgtca tcggctggca ggtgtgccgt gagctggcgg gggttgaacg
     7981 tatctatgca atgcgcaaaa aagccgttgg tctgcttggc aatgccaaag gtgccgctaa
     8041 gccaattccg tttgctgagg atacctgcgt accgccggaa cacctggcgg attatattgc
     8101 tgaatttcgc gcgctgctcg acagccacgg cttaagctac ggtatgttcg gtcacgtcga
     8161 cgcaggtgtc ttgcacgtcc gtccagcgct ggatatgtgc gatcctcaac aagagatttt
     8221 gatgaagcaa atctctgatg acgtggtggc gctgactgcg aaatacggtg gtttgttgtg
     8281 gggcgagcac ggcaaaggtt ttcgcgctga atacagcccg gcgtttttcg gtgaggaact
     8341 ttttgcagaa ctgcgcaaag tgaaagcggc atttgacccg cataaccgac tcaacccagg
     8401 gaagatttgc ccgccagaag gtctcgatgc gccgatgatg aaagtggacg cggtgaagcg
     8461 cggtacattc gatcggcaga tccccattgc ggtacgccag cagtggcgcg gtgcgatgga
     8521 gtgtaacggc aacggtttat gcttcaactt tgatgcccgt agtccgatgt gtccgtcgat
     8581 gaagatcacc cagaaccgga ttcattcacc gaaagggcgc gcaacgctgg tgcgtgaatg
     8641 gctgcgtttg ttggcggatc gcggcgttga tccactcaaa ctggaacaag aactgcctga
     8701 atccggcgtc agtttgcgga cgttaattgc ccgcacgcgc aatagctggc atgcgaataa
     8761 aggcgaatat gacttctcac acgaagtcaa agaggcgatg tcgggctgtc tggcctgtaa
     8821 agcgtgttcg acccagtgcc ccatcaaaat tgatgtgccg gagtttcgct ctcgttttct
     8881 gcagctctat cacacccgtt atttacgccc gctgcgcgac cacctcgtcg ctacggtcga
     8941 gagctacgcg ccgctgatgg cacgcgcgcc gaaaaccttt aacttcttca ttaaccagcc
     9001 gctggtgcgc aaactctcgg aaaaacatat cggcatggtt gatttgccgc tgctgtcggt
     9061 cccctcgcta caacaacaaa tggtggggca tcgctcggca aacatgacgc tggaacagct
     9121 tgaatctctc aatgcagagc agaaagcgcg cacagtgttg gtggtgcagg acccctttac
     9181 cagctattac gatgcgcaag tggtggcgga ttttgtccgt ctggtcgaaa aattaggttt
     9241 ccagcctgtg ttactgccat tttcgccaaa tggcaaagcc cagcatatta aaggttttct
     9301 taatcgtttt gcgaagacgg cgaaaaagac ggcggatttc ctcaaccgta tggcgaagct
     9361 gggtatgcca atggtgggcg tcgatccggc gctggtactt tgttatcgcg atgaatataa
     9421 actggcgctg ggcgaggagc gtggcgagtt taacgtctta ctggcgaatg aatggctggc
     9481 aagcgcactt gagtcacagc cagtggctac agtcagcggt gaatcatggt atttctttgg
     9541 tcactgtacc gaagttaccg ccttgccggg tgcgccagca caatgggccg cgatatttgc
     9601 ccgttttggc gcgaaactgg aaaatgtcag cgtgggttgc tgcggcatgg cagggactta
     9661 cggacatgaa gcgaaaaacc atgaaaattc gctcgggatc tatgagttat cctggcatca
     9721 ggctatgcag cgactgccgc gtaaccgctg tctggcgacc ggatattcct gccgtagcca
     9781 ggtaaaacgg gttgaaggca cgggggtacg ccatcctgtg caggctttac tggagattat
     9841 taaatgatat ggaaacggaa aatcaccctg gaagcactga atgctatggg tgaaggaaac
     9901 atggtggggt tcctggatat tcgctttgaa catattggtg atgacaccct tgaagcgaca
     9961 atgccagtag actcgcggac aaagcagcct ttcgggttgc tgcatggagg agcatccgtg
    10021 gtactggccg aaagtatcgg ttccgttgcc ggttatttat gtaccgaagg tgagcaaaaa
    10081 gtggttggtc tggaaatcaa tgctaaccac gtccgctcgg cacgagaagg gcgggtgcgc
    10141 ggcgtatgca aaccgttgca tctcggttcg cgtcaccagg tctggcagat tgaaatcttc
    10201 gatgagaaag ggcgtttgtg ctgttcgtca cgattgacga ccgccatttt gtgacgttgt
    10261 caccagaaaa gtgtgacgca tattgctttt ggtcattatc tgcacagtaa acggtggtat
    10321 actgtgcagg tcttgtctaa aagcgaggat gctatgtcta ctcaacttga tcccacccag
    10381 ctggccattg aatttttacg ccgtgaccag agcaatcttt cacctgccca atatctcaaa
    10441 cgtctgaaac aactagaact tgaatttgct gacctgctta ctctctcttc tgctgaatta
    10501 aaagaagaaa tctactttgc ctggcgtctg ggcgtgcatt gatcctgact taatgccgca
    10561 agttcgccaa atcgacctgg attaacctcc gtccaggttc gatgaccttc ttaatactac
    10621 ttatctaccg cctgatattg ttcaaaaata atactaatcg cagtttgtgt taaaacggcg
    10681 ggttagcttt atgagattat tcttatcgcc ccttcaagag ctaagccact gagagtgccg
    10741 gagataagcg ccggatgggg tagaaaccct taagcctgtg tcgcacagac ttaagggttt
    10801 tcttatttct gaacgctgca cttttttacc tatctcttaa atagtcattt tcaatacaac
    10861 tttttctttt tcatcacagc cttaatgctc cttagataat aaccattatc taacaatgag
    10921 atacctaatt cttagcgtgc ctgttaaccc acacatcagg gtctatgctt attaaaagca
    10981 ggcaaaaagc atgttttacg gtaaagcccc tgcgtttgct gggttgaact gataatcatt
    11041 atcactaaca tgctgttata cgctgaaagc gatgaagtga ggtaaatcga tggacatgca
    11101 ttcaggaacc tttaacccac aagatttcgc ctggcaaggc ttaacgctga cacccgcagc
    11161 ggcgatacac atccgtgagc tggtggcaaa gcagccgggt atggtcggcg tgcgcttagg
    11221 cgtgaagcaa acgggctgcg cgggctttgg ctatgtgctc gacagtgtta gcgagccgga
    11281 caaagacgat ctgctgtttg aacacgacgg cgcgaagctg tttgtcccgc tgcaagcgat
    11341 gccgtttatt gatggcacgg aagtcgattt cgttcgtgaa ggacttaatc agatattcaa
    11401 atttcacaac cctaaagccc agaatgaatg tggctgtggc gaaagctttg gggtataggc
    11461 ggtactatgt ctcgtaatac tgaagcaact gacgatgtca aaacctggac cggcggcccg
    11521 ctgaattata aagaaggatt cttcacccag ttagccaccg atgagctggc aaaggggata
    11581 aacgaagagg tggtgcgcgc aatttcggcg aagcgtaatg agccggagtg gatgctggag
    11641 tttcgtctaa acgcctatcg cgcatggctg gagatggaag aaccgcactg gttgaaagcg
    11701 cactacgaca agctgaatta tcaggattac agctactact cagcaccatc gtgcggtaat
    11761 tgtgacgaca cttgcgcgtc tgaacctggc gcggtgcagc aaactggcgc gaacgccttt
    11821 ttaagtaaag aggtggaggc ggcgtttgag cagttgggcg ttcccgtgcg ggaaggcaaa
    11881 gaggtggcgg tggatgccat tttcgactca gtttcggttg ccactactta tcgcgaaaaa
    11941 ctggcggagc agggaattat tttctgttcc tttggtgagg cgatccacga tcacccggaa
    12001 ctggtgcgta aatatctcgg caccgtggtg ccggggaatg acaacttctt tgccgcgctt
    12061 aatgcggcgg tagcctctga cggtacgttt atttatgtgc ctaaaggcgt gcgctgcccg
    12121 atggaacttt ccacctattt tcgcattaac gcagaaaaaa ccgggcagtt tgagcgcacc
    12181 attctggtgg ccgacgaaga cagctacgtc agctacattg aaggctgttc cgctccggtg
    12241 cgtgacagct atcagttaca cgcggcagtg gtggaagtca tcatccataa aaacgccgag
    12301 gtgaaatatt ccacggtaca aaactggttt cctggcgata acaacaccgg cggtattctc
    12361 aacttcgtca ccaagcgtgc tttgtgcgaa ggcgaaaaca gcaaaatgtc atggacgcaa
    12421 tcagaaaccg ggtcagcgat tacgtggaaa tatcccagct gcattttgcg cggcgataac
    12481 tccattggtg agttttactc agtggcgctg accagcggtc atcagcaagc ggataccggc
    12541 accaagatga tccacatcgg taaaaacacc aaatcgacca ttatctcgaa agggatctct
    12601 gccggacata gtcagaacag ttatcgcggc ttagtgaaaa tcatgccgac ggcaaccaat
    12661 gcgcgcaatt tcactcagtg cgactcaatg ctgattggcg ctaattgtgg ggcgcatacc
    12721 ttcccgtatg ttgagtgtcg taacaatagt gcgcaactgg aacacgaggc aacgacatca
    12781 cgtattggtg aagatcaact gttttactgc ctgcaacgcg ggatcagcga agaagacgcc
    12841 atctcgatga ttgttaacgg tttctgcaaa gacgtgttct cggagctgcc gttggaattt
    12901 gccgttgaag cacaaaaact cctcgccatc agtcttgaac acagcgtcgg ataaggaata
    12961 aacatgttaa gtattaaaga tttacacgtc agcgtggaag ataaagctat cctgcgcgga
    13021 ttaagcctcg acgttcatcc cggcgaagtt cacgccatta tggggccaaa cggttcgggc
    13081 aaaagtacct tatcggcaac gcttgccggg cgagaagatt atgaagtgac gggcggcacg
    13141 gttgagttca aaggcaaaga tttgcttgcg ctgtcgccgg aagatcgcgc gggcgaaggc
    13201 atctttatgg ccttccagta tccggtggag attccaggtg tcagtaacca gtttttcctg
    13261 caaacggcac ttaatgcggt gcgcagctat cgcggccagg aaacgctcga ccgctttgat
    13321 tttcaggatt tgatggaaga gaaaatcgct ctcctgaaga tgccggaaga tttattaacc
    13381 cgttcggtaa acgttggttt ttccggcggc gagaaaaagc gcaacgatat tttgcaaatg
    13441 gcggtgctgg aaccggagtt atgcattctt gatgagtcgg actccgggct ggatattgac
    13501 gcattaaaag tggtcgccga tggcgtgaac tcgctgcgtg atggcaagcg ctcattcatc
    13561 attgttacgc actaccaacg cattctcgac tacatcaagc ctgattacgt tcatgtgcta
    13621 tatcagggac gaattgtgaa atccggcgat ttcacgttgg tcaaacaact ggaggagcag
    13681 ggttatggct ggcttaccga acagcagtaa cgcgctgcaa cagtggcatc acttgtttga
    13741 agctgaaggg acaaaacgct ccccgcaagc acagcagcat ttacaacaat tgctgcgtac
    13801 cggactgccg acacgtaaac atgaaaactg gaaatatacg ccgctggaag ggctgatcaa
    13861 tagccagttt gtcagcattg cgggagagat atccccacag cagcgtgatg ccttagcgtt
    13921 aacgttagac tccgtgcggc tggtgtttgt cgatgggcgt tacgtgcccg cactgagcga
    13981 tgcaactgaa ggcagcggat atgaagtgag cattaacgac gaccgtcagg gtttacccga
    14041 cgctattcag gcggaagtgt ttctgcattt gacggaaagc ctggcacaaa gcgtgacgca
    14101 tatcgccgtg aagcgcggtc aacggccggc aaagccattg ctgttaatgc atatcaccca
    14161 gggcgtggca ggtgaagagg tgaacactgc ccattaccga catcatctgg atctggcgga
    14221 aggtgccgaa gcaacggtga tcgaacattt tgtcagcctg aatgatgctc gtcattttac
    14281 cggggcacgg ttcactatca acgtcgcagc gaatgcccac ttgcagcata tcaagctggc
    14341 gtttgaaaac ccgctcagtc accactttgc tcataacgat ttgttgctgg ctgaggatgc
    14401 caccgcattt agccacagtt tcctgctggg tggcgcagtg ttacgacaca acaccagtac
    14461 gcaactcaat ggcgaaaaca gcacgctgcg gatcaatagc ctggcgatgc cggtgaaaaa
    14521 cgaggtgtgt gatacccgta cctggctgga acacaataaa ggtttttgta acagccgaca
    14581 gttgcacaaa actatcgtca gcgacaaagg ccgcgcggta tttaacggtt tgatcaacgt
    14641 cgcgcagcac gccatcaaaa cggatggtca gatgaccaac aacaatctgc tgatgggcaa
    14701 actggcggaa gtggatacga aaccgcagct ggaaatctat gcagatgatg tgaaatgcag
    14761 ccacggcgcg acggtggggc gtattgatga tgaacagata ttctatctgc gctcgcgcgg
    14821 gatcaatcag caggatgccc agcagatgat catttacgcc ttcgctgccg aactgacgga
    14881 agcactgcgt gatgaggggc ttaaacagca ggtgctggcc cgaatcggtc aacggctgcc
    14941 aggaggtgca agatgatttt ttccgtcgac aaagtgcggg ccgactttcc ggtgctttcg
    15001 cgtgaggtaa acggtttgcc gctggcttat ctcgacagcg ccgccagtgc gcagaaaccg
    15061 agccaggtga ttgacgccga ggccgagttt tatcgtcatg gctacgcggc ggtgcatcgt
    15121 ggtattcata ccttaagcgc ccaggcgacc gagaaaatgg agaacgtgcg caagcgggca
    15181 tcgctgttta ttaatgcccg ttcggcggaa gagctggtgt tcgtccgcgg cacgacggaa
    15241 gggatcaatc tggtcgccaa tagctggggc aacagcaacg tgcgggcggg cgataacatc
    15301 atcatcagtc agatggagca ccacgctaac attgttccct ggcagatgct ttgcgcacgc
    15361 gttggcgcag agctgcgtgt gatcccgctc aatcccgatg gtacgttgca actggagacg
    15421 ctgcctacgc tgtttgatga gaaaactcgc ctgctggcaa ttactcatgt ctccaacgtg
    15481 cttggcacag aaaatccact ggcggaaatg atcacgcttg cgcaccagca tggcgcaaaa
    15541 gtgctggtgg atggcgctca ggcggtgatg catcatccgg tggatgttca ggcgctggat
    15601 tgcgactttt acgtgttctc cgggcataaa ctgtatggcc ccaccggaat tggcattctt
    15661 tatgtgaaag aagccttgtt gcaggagatg ccgccgtggg aagggggcgg ttctatgatc
    15721 gccaccgtca gcctgagtga aggcactacc tggaccaaag caccatggcg gtttgaagcc
    15781 ggtacaccca ataccggggg catcattggt cttggcgcgg cgctggagta tgtttcggcg
    15841 ctggggctta ataacatagc cgagtatgaa cagaatctga tgcattatgc gctatcacag
    15901 ctggaatctg taccggatct cactctctat ggcccacaaa acaggcttgg cgttattgct
    15961 tttaatctcg gtaaacacca cgcctatgat gttggcagtt ttctcgataa ttacggcatt
    16021 gctgtgcgta ccggacatca ctgcgcaatg ccattgatgg cctattacaa cgtccctgcg
    16081 atgtgtcggg cgtcgctggc catgtataac acccatgaag aagtggatcg tctggtgacc
    16141 ggcctgcaac gtattcaccg tttgctggga taacagggag gcactatggc tttattgccg
    16201 gataaagaaa agttgctgcg taatttttta cgctgcgcca actgggaaga gaaatatctc
    16261 tacattattg agctgggcca gcgtctgcca gaattacgcg acgaagacag aagtccacaa
    16321 aatagcattc agggctgtca gagtcaggtg tggattgtca tgcgccagaa tgcccaggga
    16381 attattgaat tacagggcga cagcgatgcg gcgattgtga aagggcttat tgcggtcgtc
    16441 tttattctct acgatcagat gacgccgcag gatattgtca atttcgatgt gcgtccgtgg
    16501 tttgaaaaaa tggcgctcac ccaacatctc accccatctc gttcacaagg tctggaagcg
    16561 atgattcgcg caattcgcgc caaagccgct gcacttagct aaactaaaag gacagctttc
    16621 atccggttgg ctcacattgc cggatggtca atgtttacac tgacctgcac aggagtgttt
    16681 tggtttcagg tgaacataag cgccatccga cgtttcagcg tgagtctccg gcaaatacag
    16741 gaggtttaca atgaaacgcg cgtctttgct tacactcacg cttatcggcg cttttagcgc
    16801 catccaggct gcctgggcgg ttgattatcc gctaccacca accggaagcc gactggttgg
    16861 gcaaaatcaa acgtatacgg tgcaagaagg ggataaaaac cttcaggcta ttgcccgacg
    16921 ttttgatact gcggcaatgt tgatccttga agccaataac actatcgccc cggtgccaaa
    16981 acctggtacg acgataacta ttccttcaca actgttatta cctgatgcac cgcgtcaggg
    17041 gattatcgtt aaccttgcag agctgcgcct ttattattat ccgccgggag aaaatattgt
    17101 gcaggtttat ccaataggta ttggattgca ggggctggaa acgccggtga tggaaacgcg
    17161 tgttgggcag aaaatcccta acccaacctg gacgcctacg gcaggcattc gtcagcgttc
    17221 gctggagcgt ggcattaaat taccgccagt cgttcctgcc ggaccaaata acccgctagg
    17281 acgttacgca ctgcgcctcg cgcatggtaa tggcgaatac ctcattcatg gtaccagtgc
    17341 gccggacagc gtcggtttgc gcgtcagttc agggtgtatt cgcatgaatg caccggatat
    17401 taaagccttg ttctccagcg tgcggacggg aacgccggtg aaagtgatca acgaaccggt
    17461 gaaatattcc gtggagccta acgggatgcg ttatgttgaa gtacatcgac cactatcggc
    17521 agaagaacag cagaacgttc agacaatgcc atacacactg ccagcaggct ttacgcaatt
    17581 taaagacaat aaggctgtag atcagaagtt agtcgataaa gcgttgtatc gtcgggcagg
    17641 gtatccggtt tcggtgagca gtggagcaac tcccgcagcc agcaatgcgc cttcagtaga
    17701 gtcagcgcag aatggtgaac cagagcaagg gaatatgtta cgcgtgacgc agtagcggta
    17761 aacggcagac aaaaaaaatg gcgcacaatg tgcgccattt ttcacttcac aggtactatt
    17821 acttgcggta tttagtagcc atgttgtcca gacgctggtt agcacgagct gcgtcatctt
    17881 tagcagcctg aacgtcggaa cgcattgcgt tcacgtcgtt gctcagctgg tcaactttag
    17941 cgttcagagt ctgaacgtca gaagacagct gatcgatttt agcgttgctg gagcaacctg
    18001 ccagcagagt agaacccagg attaccgcgc ccagtaccag tttagtagct ttcattatta
    18061 ataccctcta gattgagtta atctccatgt agcgttacaa gtattacaca aagtttttta
    18121 tgttgagaat atttttttga tgggaaggca cttatttttg atcgttcgct caaagaagca
    18181 tcgaacgctg ggttttagat aaaaaaattg agagaaaaca ggatgcttcc atcggattca
    18241 tcttagataa agtgagatta tatagtgaaa tccgatttga ttttttattg cttctggtta
    18301 tcgattaaat aaaaaaagcg cccatcaggg cgcttcgata tacaaattaa ttcacaaaag
    18361 caatattaca ggacgtgaac agatgcggtg ttagtagtgc cgctcggtac cagtgcacca
    18421 gaaaccataa ctacaacgtc acctttgtgt gccagaccgc tctgcagagc cagttcttta
    18481 cccagacggt agaaatcatc agtagaagtg atctctttaa caagctgcgg cacaacgcct
    18541 ttgctcagta ccaactgatg agccgttttt tcgttggtgg tcagtgccag gatggtggca
    18601 tccgggaagt atttacgtac tgcgcgagca gatttaccgc cctgagtagc aaccacgatc
    18661 agcggagcat ccagtttttc agcagtttca acggcaccac ggcataccgc ttcggtaatg
    18721 cgcagtttac ggttgtcatt gttgaactcg agacggctgt tcatcacgcg gtcggtacgt
    18781 tcgcagatgg tcgccatgat agaaaccgct tccagcgggt atttaccttt tgcggattca
    18841 ccagacagca tcactgcgtc agtaccgtcg aggatggcgt ttgcaacgtc accggcttct
    18901 gcgcgagtcg ggcgtgggtt tttgatcatg gaatccagca tctgggtcgc agtgataacg
    18961 actttacgtg cacggataca tttttcgatc atcatcttct gggcgaagat aacttcttct
    19021 accgggattt ctacacccag gtcgccacgc gcaaccatga tgccgtcaga ggcttcgagg
    19081 atttcgtcga agttgttgag gccttcctgg ttttcgattt tggagatgat gtggatgttt
    19141 tcgccgccgt gcgctttcag gtgctcacgg atttcgataa cgtcagaacg cttacgaata
    19201 aaggaagcag caacaaagtc tacgccttgt tcgcaaccaa agatcaggtc ctgtttgtct
    19261 ttttcagcca gtgctggcag agcaatggaa acgccaggca ggttcacacc tttgttttcg
    19321 cccaggtcac cgttgttcag cactttacag ataactttgt taccttcaat ggcggtaact
    19381 tccataccga tcagaccatc gtcaaccagt acggtgttgc caacagacag gtcagtagtg
    19441 aaaccttcat acgttaccgc aaccatttcg ctgttgccga taacagattt atcagtggtg
    19501 aaagtaaagg tctgaccagc tttcagagaa acgtcgttac cgccttccag tttcatggtg
    19561 cggatttccg gacctttggt atcaagcagg atagcggcgg ttttaccagt tttgctcatc
    19621 acgttgcgca gattctgaat gcgctgaccg tgttctgcat agtcaccatg agagaagttc
    19681 agacgcataa cgttcatgcc agcgtccagc attttagcta acatctcttc agattcggtt
    19741 ttcggtccga tggtgcaaac aattttggtc tttttcatga cagtcttagt ctttaagttg
    19801 agaaggatgg gagaaacttg ctttctgggc gcactgccgg aaagcgaatc cggtattacg
    19861 aaagtggtgg tgcctcgctc taaggatagg tgacatcgaa aaagcgtgca gaggaatgtg
    19921 tgcttgtgtc tcagcccaac gtgagtgcct gtttttgagt cgttgagttc tacagtccaa
    19981 agtgctgaaa ccattcaaga gtcaattggc gcgcattata cgctgaaatt aatccaaaag
    20041 gaaaacaaaa acagcgtttc aaaaaatata caacttgtta gacaataaat tgttatcaaa
    20101 gatttaacgt tccagggaaa aggttacgca aaaacttcac tgtttgcgca acgtctggtg
    20161 ccgaagttgt cagtgtgagg ataag
//
LOCUS       DAPHKZ010000080        19885 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.080, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000080 DAPHKZ010000000
VERSION     DAPHKZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19885
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.080"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            145..687
                     /locus_tag="RH288_003016"
     CDS             145..687
                     /locus_tag="RH288_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaZ family protein"
                     /protein_id="HDV4032054.1"
                     /translation="MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTETT
                     GLALSGNWTHNDDDGDVAGVGLGLNLPLGPLMATVGGKGVYTNPNYGDEGYAAAVGGG
                     LQWKIGNSFRLFGEYYYSPDSLSSGIQSYEEANAGARYTIMRPVSIEAGYRYLNLSGK
                     DGNRDNAVADGPYVGVNASF"
     gene            787..1989
                     /locus_tag="RH288_003017"
     CDS             787..1989
                     /locus_tag="RH288_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HDV4032055.1"
                     /translation="MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVG
                     DNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMER
                     YFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVM
                     VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPII
                     ELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQF
                     TGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEH
                     LNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEV
                     VESMTLSV"
     gene            2209..2991
                     /locus_tag="RH288_003018"
     CDS             2209..2991
                     /locus_tag="RH288_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDV4032056.1"
                     /translation="MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYL
                     LLNELRRQRFLSLDHQENFCLWTRLVELSGHALSKMDLRELARPRLTQLMDTTGLLCH
                     LGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGL
                     VWEQATPTTITHPQQLHEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAIS
                     VVGTRLQINEEYRDYLAGKAIACARDISRLLGWKSPFDLQAS"
     gene            3006..4211
                     /gene="rhmD"
                     /locus_tag="RH288_003019"
     CDS             3006..4211
                     /gene="rhmD"
                     /locus_tag="RH288_003019"
                     /EC_number="4.2.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnonate dehydratase"
                     /protein_id="HDV4032057.1"
                     /translation="MTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATP
                     MSKYRDYEQSRQSFGINVLGTLVVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEG
                     KCVSDIKLIHDQMLSATLYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAV
                     RDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFW
                     LMLDCWMSQDVNYATKLAHACAPYNLKWIEECLPPQQYESYRELKRNAPVGMMVTSGE
                     HHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQLVVPHGSSVYSHHA
                     VITFTNTPFSEFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRD
                     CNLKRPYSH"
     gene            4268..5557
                     /locus_tag="RH288_003020"
     CDS             4268..5557
                     /locus_tag="RH288_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416749.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4032058.1"
                     /translation="MSTALLDAVVKKNRVRLIPFMLALYVLAFLDRSNIGFAKQTYQI
                     DTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGARTWIGTTTLLWGFLSAAMAWAD
                     TEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
                     GALLEMHGFMGHPGWFWMFVIEGLLAVGAGVFTFFWLDDTPEQARFLSKQEKTLLINQ
                     LASEEQQKVTSRLSDALRNGRVWQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFT
                     ASVVTAIPWVAALFGTWLIPRYSDKTGERRNVAALTLLAAGIGIGLSGLLSPVMAIVA
                     LCVAAIGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFA
                     SDAAGLLTLAAVAVIGSLIIFTLRVNRTVAQTDVAHH"
     gene            5575..6378
                     /gene="yfaU"
                     /locus_tag="RH288_003021"
     CDS             5575..6378
                     /gene="yfaU"
                     /locus_tag="RH288_003021"
                     /EC_number="4.1.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy-L-rhamnonate aldolase"
                     /protein_id="HDV4032059.1"
                     /translation="MNALLSNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLL
                     IDGEHAPNTIQNLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTA
                     EQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDN
                     LDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAV
                     APDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRIKGSY"
     gene            complement(6419..6616)
                     /locus_tag="RH288_003022"
                     /pseudo
     CDS             complement(6419..6616)
                     /locus_tag="RH288_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6617..7516)
                     /locus_tag="RH288_003023"
     CDS             complement(6617..7516)
                     /locus_tag="RH288_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HDV4032060.1"
                     /translation="MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQT
                     LRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAA
                     MQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
                     IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQ
                     CGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLE
                     QGFEREIVLATTQLTDADIPNCH"
     gene            complement(7709..8899)
                     /gene="glpC"
                     /locus_tag="RH288_003024"
     CDS             complement(7709..8899)
                     /gene="glpC"
                     /locus_tag="RH288_003024"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HDV4032061.1"
                     /translation="MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMG
                     SVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWR
                     KLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRNIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLA
                     QALA"
     gene            complement(8896..10155)
                     /gene="glpB"
                     /locus_tag="RH288_003025"
     CDS             complement(8896..10155)
                     /gene="glpB"
                     /locus_tag="RH288_003025"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HDV4032062.1"
                     /translation="MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGS
                     LDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQL
                     QGSVELAHQRVTPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
                     ELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMI
                     LMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPG
                     DEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLD
                     VLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIA
                     QGCGGGVCAVSALHAAQQIAQRAGGQQ"
     gene            complement(10145..11773)
                     /gene="glpA"
                     /locus_tag="RH288_003026"
     CDS             complement(10145..11773)
                     /gene="glpA"
                     /locus_tag="RH288_003026"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HDV4032063.1"
                     /translation="MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLS
                     FQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAE
                     YADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYN
                     EIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEP
                     AEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVEN
                     LNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKG
                     VQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL"
     gene            12046..13404
                     /gene="glpT"
                     /locus_tag="RH288_003027"
     CDS             12046..13404
                     /gene="glpT"
                     /locus_tag="RH288_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HDV4032064.1"
                     /translation="MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTI
                     ATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQERN
                     GG"
     gene            13409..14485
                     /gene="glpQ"
                     /locus_tag="RH288_003028"
     CDS             13409..14485
                     /gene="glpQ"
                     /locus_tag="RH288_003028"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDV4032065.1"
                     /translation="MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLP
                     EHTLPAKAMAYAQGADYLEQDLVMTKDDNLVVLHDHYLDRVTDVADRFPDRARKDGRY
                     YAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
                     STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRI
                     KNELEPKMGMELNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADG
                     IGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTPDVNQLYDAL
                     YNKAGVNGLFTDFPDKAVKFLNKE"
     gene            complement(14527..14769)
                     /locus_tag="RH288_003029"
                     /pseudo
     CDS             complement(14527..14769)
                     /locus_tag="RH288_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311149.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            14948..15598
                     /gene="inaA"
                     /locus_tag="RH288_003030"
     CDS             14948..15598
                     /gene="inaA"
                     /locus_tag="RH288_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA"
                     /protein_id="HDV4032066.1"
                     /translation="MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKL
                     YVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALL
                     VTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIY
                     VKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM"
     gene            complement(15652..15906)
                     /gene="yfaE"
                     /locus_tag="RH288_003031"
     CDS             complement(15652..15906)
                     /gene="yfaE"
                     /locus_tag="RH288_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HDV4032067.1"
                     /translation="MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGS
                     CRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(15906..17036)
                     /gene="nrdB"
                     /locus_tag="RH288_003032"
     CDS             complement(15906..17036)
                     /gene="nrdB"
                     /locus_tag="RH288_003032"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="HDV4032068.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDL
                     FVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL"
     gene            complement(17270..19555)
                     /gene="nrdA"
                     /locus_tag="RH288_003033"
     CDS             complement(17270..19555)
                     /gene="nrdA"
                     /locus_tag="RH288_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HDV4032069.1"
                     /translation="MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPAL
                     YDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLVPSIQDDGCESGACKI"
BASE COUNT         4596 a         4886 c         5422 g         4981 t
ORIGIN      
        1 ttttttcggc atttaattat ttaagaagta tttagttaca ataagtgact agatcctttt
       61 tttcgctcat tgaatcctct gtgccaggca gtacaatccc gcagctttgg gaattttgat
      121 taattgcttg tgggaaaggg gataatgaaa aaaattgcgc tagcaggtct ggccggaatg
      181 ctgttggttt ctgcatcggt caatgcaatg agcatcagcg gtcaggcggg taaagaatac
      241 accaatattg gtgtcggttt tgggactgaa acgacgggcc tggcgttaag cggtaactgg
      301 acacataacg acgacgacgg tgatgtcgct ggcgtggggc tggggttgaa tctgcctctc
      361 gggccgttaa tggcgaccgt tggcggaaaa ggcgtttaca ccaacccgaa ttacggcgat
      421 gaaggttatg ccgcagcggt aggaggtggt ttgcagtgga aaattggcaa cagcttccgt
      481 ttgtttggcg agtattacta ctctccggat tcgctctcca gcggtattca aagttatgaa
      541 gaagcgaatg ctggcgcgcg ttacaccatt atgcgtccag tcagtattga ggcgggttat
      601 cgctacctga atctgtcggg taaagacggt aaccgcgaca acgccgtggc tgacggcccg
      661 tatgttgggg ttaacgccag tttctgatcc cttccggcgc ggcattctgt cgcgccattc
      721 agtttcttac tacgccttat ctccctttgc gttatagtga ttcgataaca aaagcaggag
      781 ataaccatgt taaaagtgga aatgttatcc accggggatg aagtgttaca cgggcaaatc
      841 gttgacacta acgctgcctg gctggccgat tttttctttc atcaggggtt gccattatct
      901 cgccgcaata cggtggggga taaccttgat gacttagtca ccattcttcg cgaacgtagt
      961 cagcacgccg atgtgctgat cgttaacggc gggctgggac cgaccagcga tgatttaagc
     1021 gcactcgccg ctgcgacagc aaaaggtgaa ggcctggtgc tgcatgaagc ctggctcaaa
     1081 gagatggaac gctatttcca cgaacgtgga cgagtaatgg caccgagcaa ccgtaaacaa
     1141 gcggagctgc ctgccagtgc tgaatttatc aataacccgg taggcaccgc ctgtggtttt
     1201 gccgtgcagc ttaatcgttg cctgatgttc tttactcccg gcgtaccgtc agaatttaag
     1261 gtgatggtcg agcacgaaat cctgccgcgc ctgcgcgagc gtttttcttt accgcagccg
     1321 ccggtttgtc tgcgtttgac tacttttggt cgttcggaaa gcgatctggc acaaagcctg
     1381 gacactctac aactgccgcc gggcgtaaca atgggctatc gctcctcaat gcctatcatc
     1441 gaactgaaac tcaccggacc ggcaagcgag caacaggcga tggaaaaact gtggctggat
     1501 gttaaacgtg ttgccggaca gagcgtgatt ttcgaaggca ctgaaggact gcccgcgcag
     1561 atcagtcgcg aattgcaaaa ccgccagttc agcctgacgt tgagcgagca attcaccggt
     1621 ggtttattgg ctttgcaact ttctcgcgca ggtgctccat tgctggcgtg tgaagtggtt
     1681 ccttcacagg aggaaaccct ggcgcaaact gcgcactgga ttacagaacg gcgggccaac
     1741 cattttgccg ggctggcact ggctgtttcg ggtttcgaga acgagcatct caactttgcg
     1801 ctagccacgc cagacggcac tttcgctctg cgtgtgcgtt tcagcactac gcgctacagc
     1861 ctggctatcc gtcaggaagt gtgcgcaatg atggcactga atatgctgcg ccgttggtta
     1921 aacggccagg atatcgccag tgagcatggc tggattgagg ttgttgagtc catgacctta
     1981 tctgtctgat tccgccactc tgtgccggtt tactgcaccg gcacattccc cctccggcaa
     2041 aatttgtcca acctgttgta ctcaataaga aaaaatccgt gcgctgattc acaaatttgt
     2101 gcgtaatttc tccagtctgc tggacgagga gcgggatttg atgcgcttca caattttact
     2161 ccccctgagc aacgagactg attccagtat ctaagactgg agtccagtat gttggaatca
     2221 agcaaagttc ccgccctgac acgggctatt gatattctca atttgattgc ccgcattggc
     2281 ccctgtagtg ctgcgacgat cattgacaca ttgggaatcc ctaaaagcac ggcctatttg
     2341 ctgcttaatg aactcaggcg tcagcgtttt cttagccttg atcaccagga aaatttttgt
     2401 ttgtggacca ggctggtgga gctttccggt catgcgttaa gcaagatgga tctccgggaa
     2461 ctggctcgac cgcgtttgac gcaactgatg gataccaccg ggctgttatg tcacctgggg
     2521 attattgata acggcagcgc ttattacatt ttgaaagtgg agtcatcagc cactatcagc
     2581 gtgcgttccc atgaaggaaa aagcctttcg ctttatcgct ccggaatagg taaatgcctg
     2641 cttgcctggc aacctgcagc ggtacagcaa agtattatcg aagggctggt ctgggagcag
     2701 gcgacaccca caacgattac tcatccacag caacttcacg aagaactggc gcgtattcgc
     2761 cgtcagggct ggagctatga caacggcgaa gattacgccg atgtccgttg tgtcgctgcg
     2821 ccggtgttta acgccaataa cgagcttacc gctgcgatct cggtggtcgg tacccgctta
     2881 caaatcaatg aagaataccg tgattatctg gcgggcaagg ccattgcctg cgccagggat
     2941 atttcacgtc tgttgggatg gaaaagtccc tttgacttac aagcctcata acaatggaga
     3001 acatcatgac cctaccaaaa attaaacagg ttcgcgcctg gtttactggc ggtgcgacag
     3061 cagaaaaagg cgctggcggc ggtgattatc acgaccaggg ggcgaatcac tggatagacg
     3121 atcatattgc caccccgatg agtaaatacc gcgattacga gcagtcacgc cagtcatttg
     3181 gcattaacgt tcttggcacg ttggttgttg aagtcgaagc agaaaacggc cagaccggat
     3241 tcgccgtttc gacagccggt gaaatgggct gttttattgt cgaaaaacat cttaaccgtt
     3301 tcattgaggg taaatgtgtc agtgatatca aactgatcca cgatcaaatg ctcagtgcca
     3361 ccctgtatta ctccggctct ggtggcctgg tgatgaatac gatttcttgt gtcgatctgg
     3421 ctctgtggga tctgttcggc aaagtggtcg ggcttccggt ttataaactt ttaggcggcg
     3481 ctgttcgtga tgagattcag ttctacgcca caggtgcgcg tccggatctg gcaaaagaga
     3541 tgggctttat cggtggcaaa atgccgacgc actgggggcc acatgatggc gatgcgggga
     3601 tccgcaaaga tgccgctatg gtcgcggata tgcgtgaaaa atgcggtgag gatttctggt
     3661 taatgctcga ctgctggatg agtcaggacg tgaactatgc gaccaaactg gcccacgctt
     3721 gcgcgcccta taacctgaaa tggatcgaag agtgcctgcc gccacagcag tatgaaagtt
     3781 atcgcgaact gaaacgcaac gcgccagtcg gaatgatggt caccagcggt gagcaccacg
     3841 gcacactgca atcttttcgt acgctttcag aaaccggtat cgacattatg cagccggatg
     3901 ttggctggtg cggtggttta accacgctgg tggaaattgc cgcaatcgcc aaatccaggg
     3961 ggcaactggt ggtgccgcac ggttcgtctg tttactctca ccatgcggtg atcaccttca
     4021 ccaatacgcc attcagcgaa ttcctgatga ccagcccgga ttgttcaacg atgcgtccgc
     4081 agtttgaccc gattctgctc aatgagccgg ttccggtgaa tggtcgtatt cataaatcag
     4141 tgcttgataa acccggtttt ggcgtcgaac tcaatcgtga ctgcaatttg aaacgcccct
     4201 acagccacta atcactccgg gcgttgctgt gacaacggta acgcccacat attctaagga
     4261 gctttttatg agcaccgctt tgcttgacgc cgtggtgaag aaaaaccgtg tgcgtttaat
     4321 tccgtttatg ttggcgctgt atgtgctggc gtttctcgac cgttcgaata tcggttttgc
     4381 caaacagacc taccagattg ataccgggtt gagtaatgaa gcttatgcgc tgggagcagg
     4441 cattttcttt gtggtatatg cgtttctggg tgttccggcg aatcttttga tgcgcaaact
     4501 gggggccaga acctggattg gtacgacaac actgctgtgg ggatttcttt cggcagccat
     4561 ggcatgggcc gatactgaag cgaaatttct gatagttcgc actctgcttg gtgctgcgga
     4621 ggccggattt ttccctggta tgatttatct cacctcgcaa tggtttccgc agcgtaatcg
     4681 cgccagcatt atggggctgt tctatatggg cgcaccgctg gcgttaacac tgggatcacc
     4741 gctttccggc gcgctgttgg agatgcatgg atttatgggg catcccggct ggttctggat
     4801 gtttgtgatt gaaggattgt tggcagtcgg tgctggggta ttcacattct tttggcttga
     4861 tgacacaccg gagcaggcac gttttctgag taaacaagaa aaaacgttgc ttatcaatca
     4921 actggcaagt gaagaacaac agaaagtgac ttctcggctg agcgatgcgc tgcgtaatgg
     4981 ccgagtctgg caactagcga ttatctacct gaccattcag gtggcggttt acggattaat
     5041 tttcttcctg ccgacccagg ttgcggcatt gctgggaaca aaagtgggct ttacagcgtc
     5101 ggtggtcacc gccattccgt gggttgcggc cttgtttggg acctggctta ttccgcgcta
     5161 ttccgataaa accggcgaac ggcgtaatgt cgcagcgctg acattactgg cggcgggcat
     5221 tggtattggt ctgtccgggc tgctttctcc agtaatggcg atcgtagcgc tgtgtgttgc
     5281 agctatcggg tttattgccg tgcagccagt gttctggacg atgccgacac aactgctttc
     5341 cggtacggcg ctggctgcgg gaattggttt tgtaaacctg tttggtgcag tgggcgggtt
     5401 tattgccccg atcctgcgcg tgaaagcaga aacgttattt gccagcgatg cggcgggatt
     5461 actgacgctg gcagcggtgg cggtcatcgg ttcgctgatt attttcactc tgcgtgtaaa
     5521 tcgcactgtt gcgcagaccg acgtggcaca tcattaaata ggttaaggaa cacgatgaac
     5581 gcattattaa gcaatccctt taaagaacgt ttacgcaagg gcgaagtgca aattggtctg
     5641 tggttaagct caacgactgc ctatatggca gaaattgccg ccacttctgg ttatgactgg
     5701 ttgctgattg acggggagca cgcgccaaac accattcaga atctttatca tcagctacag
     5761 gcggtagcgc cctatgccag ccaacccgtg atccgtccgg tggaaggcag taaaccgctg
     5821 attaaacaag tcctggatat tggcgcgcaa actctactga tcccgatggt cgatactgcc
     5881 gaacaggcac gtcaggtggt gtctgccacg cgctatcctc cctacggtga gcgtggtgtc
     5941 ggggccagtg tggcacgggc tgcgcgctgg ggacgcattg agaattacat ggcgcaagtt
     6001 aacgattcgc tttgtctgtt ggtgcaggtg gaaagtaaaa cggcactgga taacctggac
     6061 gaaatcctcg acgtcgaagg gattgatggc gtgtttattg gacctgcgga tctttctgcg
     6121 tcgttgggct acccggataa cgccgggcac ccggaagtgc agcgaattat tgaaaccagt
     6181 attcggcgga tccgtgctgc gggtaaagcg gctggttttc tggctgtggc tcctgatatg
     6241 gcgcagcaat gcctggcgtg gggagcgaac tttgtcgctg ttggcgttga cacgatgctc
     6301 tacagcgatg ccctggatca acgactggcg atgtttaaat caggcaaaaa tgggccacgc
     6361 ataaaaggta gttattgata tcaaaggccc atggggatcg gctgtgggcc tgtgttaatt
     6421 agtggttatt cgctgccaga tcggcttcgc ttagctgggt ggccgcgagc acctggtcac
     6481 gatcaaagcc ctgttccagc atgcgcaaag caattttaat ggcttgttca tgcaaacctt
     6541 ctaatttacc ttcctgccag ccaatttgat gtccttcctg ccgcagccgt tcagcaatag
     6601 tcattaatct ctccttttaa tgacagttcg gaatatcagc atcagtgagt tgggttgtcg
     6661 ccagcacaat ctcacgttca aagccctgct ccagcatgcg caaagcaatt ttaatggctt
     6721 gttcatgcat accttcctgc cagccaattt gatgcccttc ctgccgtagc cgttcagcaa
     6781 tagtcattaa tctctccttt tgtagtggtg aacgttcggc aatctcctca ataaaacggg
     6841 tgaaacggga ggtatcgccg cattgcagca gataattaaa cagtgtttgt agctggctgt
     6901 cattagtgaa gcctctaacc aaaagcgtgg tgatcctgtc gaccatgccg attaaatcgc
     6961 ggtcgcgaat atgcttttga atcagttcca gcagagctat acgccgatgt tgcatgatct
     7021 catcgtcagg tacgatggtg atatccacca acggaaaagc ttcggtgtac aactgccggg
     7081 caagttgcgg atcgtcaaac tcatccagcc agttgagtga gtacgggtaa ggcgaggttt
     7141 cgccatgata aaacagcaac ggcaccacca gcgggactct gtcatagcct ttgtccaggt
     7201 gacgctgcat ggcggcagtg gcatagcgca ttagccgaaa agccatattc ttttctgcag
     7261 agctttgatg ttcaatcacg cagtagatat agccgtcacc gtcgctggtt tccacggacc
     7321 acaaaacatc cgagtagtaa gcgcgtaaac ttttttcaat aaaactagtg ggttccaggc
     7381 gtaaggtttg caggttgcaa agcttgcgca gtggttctgg taaatgtatt tcgagaaaat
     7441 cccgtgcggt ttcgggtgtg aacataaagg ttttaaatac cgcatcatgc ggggaggagg
     7501 ttgttgattc ggtcatggtt gtccgtcacc tgatatttat gatgacgcga cattacggtt
     7561 atcccaggcc tttgacatct gccagtttca gcctttgcga gacgttttca gaggaatttt
     7621 cactgcgttg caacgcatac attgggcacg gaatcgtgta cgcaaaaatg cccggtaacc
     7681 acatgcttac cgggcatcag aaaggagttt aagccagcgc ctgggccagt agcgtaatcg
     7741 gatgttcgca gcgaagactt gtggacatct caatctgcca tttacaggtt tcgcagtcgg
     7801 tgaccaccag atctgcgccg ctttcttcta tctggcggaa cagtggtgcg ccgatggctt
     7861 gtgaggtggg gtagttctct tttttgaaac cgtaagtacc cgcaataccg cagcactggg
     7921 aatccagcac cgttaactca agccccggga tgttacgcaa cagctccagg gtgtagagcg
     7981 tccagcccat tttttccata tggcacggag tgtgataaac cactttcagc ggcagcggtt
     8041 tcagcggtaa cgttttgcct tcgtccagct tgcgccacag ccagcgggtt gccagttcga
     8101 tatgatcgcg caagcctttg ttgtcgacat tcagcacttc cgggtattcg tcgcgcaggg
     8161 caaatgtaca ggttgaggag gtggcaatca ccggaatgcc ttttactccc acagcttcgc
     8221 ggatcgactc tacattcgta attgcctgtt tgcgtgcttt atcggtaaag ccgttggcga
     8281 ttagcggtac gccgcagcat ttttctttgc tgagcagttg tacaccggta cccattgcgt
     8341 tgagcacttt aattaaatct ttacctaact gcggatggtt gtagttaacg aagcagccgt
     8401 gaaagaaagc gacctggtct ttatattgtg cttgctgagc cgccacgctg cgataccagc
     8461 gacggaacgt gccgaaggag tatttcggta gcgtgcggcg atgatcgatt tttaacgccg
     8521 catcaagcag ctgccgcacc ggtttcagcg aggtagcggt gttgacgatt ggtgcgaacg
     8581 gcgtggaaac gctacccatc aggtcggtat gactcaacac aaaattacgc agcgacgggc
     8641 gcgtggtgtc atatttcgcc cgcgcgcgct ggataatatc gccaatcttc acatcggacg
     8701 ggcaggcgac ttcacaacgt ttgcagttga tgcaatattt cagcgcctcg tcatacagtg
     8761 cgccatcttt caaacgcaga cgctcgccat ccggcccggc ttgttttggc cctggataac
     8821 cgggattcac ccggctcacc gggcaggcgg tggtgcagac ggtgcactta atgcagtttt
     8881 cgaagctggt gtcattcatt gttggcctcc tgcgcgttgg gcaatctgtt gagcggcatg
     8941 taaagcactg acggcacaaa caccgccgcc gcatccctgg gcgatgggat caaatccgcc
     9001 cagcaccgaa ccgatggcaa acaggttttc aatggtttgc cctgcctgtg acgggcgtag
     9061 cgtctcatca gtggttacac cgaactgctg ccacggttgc ggcgcaaaaa aatctccctt
     9121 ataccattca ccccgcgtgg cggtttgtag cacatcaagg ccgagaatcg gctctcgaat
     9181 gccgttacgt tccgctacca gtccgccact aaagaaactg ccgctggcga gaaccgcgaa
     9241 acgtggacgt agcggaatat cggcgtgatt gcgggtccag atttcgttca ctacgccatt
     9301 tttacaggtc acttttttca cttcatcgcc cggcatccac acgccaccct ggcgcacaaa
     9361 ctggcgctgt aactggtttt gcagacgaat gcccagcacg gaaggcggca gcgttggcaa
     9421 aagcatcagt gaacaaggta gtttttcatt caaccaacgc cacagtttgt catcggccag
     9481 accgaagcag gcgggcatca ggatcatttc gcaggtattg gcgacaggaa taagcgcatc
     9541 aagtaacagc ggccagtttt cttcattatc aaggaaacgg gcgatattca ccgcgcgaaa
     9601 ttcggtggcg ttattgcgca gcacatccag ttccggcagc tctatttctg cggtttcaac
     9661 ggcaaggccg agttcacgca acgaagctgc cgcaaggtgc gcctgaaaat ccatcaggcc
     9721 gctaattccc actacacata ttttcttcgc gggcagcggc cagacgggga cttctggcga
     9781 acttagccag gtagagcgca gagtgccgag cggcgtaacc cgctggtgag caagttctac
     9841 gctgccctgc aattgcgcac cgctttcagc gattaatgcc tgcgcctggc aagcgagatc
     9901 gagcacgcgt tgtggctcga gaagggagta aggatgggct ggtgcctgct gacgcaaaga
     9961 ttccagtcca ctgtgaatgt ctgtcaccgg ttgaccatct ggcagatggc tcagcaaatc
    10021 cagcgatccg gatgagaaat gcagtgcgct ttgaccacga gtgacaatgg cacagcgcag
    10081 gccgtgtttt tgcagttgca ggccacagag taatccggcg aggccgccgc ccataatgac
    10141 agtatcaaag cgcatctttc tgctccttct ccagaccaca caatccctga taaacccagc
    10201 gggtaaattc gctttcgcgc agtgcatctc cccaggcgat gggttgcacg cctttccagc
    10261 gttcgttaag gaaggtggaa agttgctcga tagattgcgc ggacgtcgtg acgttaaaac
    10321 gttgcagcag tccggcagcg cggcaggcgc agagttcgcc ctggcaggtg cccatcccca
    10381 cacgggtacg acggcgtaaa tccagcaggc tattaacgtt taaattttct accgcgtact
    10441 gcacttcacc cgcagttacc gcttcgcact cacataccag gctacggtgc agacggcctt
    10501 cgctcagcca ggcaggcgtg cgatcgccat gacgataaac cgcagaaccg cgcagcgggg
    10561 caggcaggga gatgacttta cgcaaggtaa cttcagcggg ttcttgtgaa ccaggcagtg
    10621 ccagatcggc agtcgtacag gggcgcgtgt tgcccagttt gcggcatacc gcgtcggtag
    10681 cccattcagc catcagccga taggtcatca gtttgccacc ggtgatggtg ataaatccgt
    10741 ccagaccatc gcgttcagca tggtcgagca gcacgatgcc acggctgacg ttacgtccgc
    10801 tcgggtcgtc atcgctggca accagcgggc gcacgccaga ataggcccgc aaaatgcgcg
    10861 ttttcgccat cacgggggcc agtttttccc cttcacgcag cagaatatca acctcttctg
    10921 ccgtcactcg attatcgtca atctcgttgt aatcaatacg taaagaggtg gtaccaatca
    10981 gcgaaatggt atcgccaggc accagaatat cggcgtcgga aggtttacgg cagcggttga
    11041 tcacatgctg gttaatgcgg tgatccatga tcagcagcga tcctttcgcc gggaacatgc
    11101 gaatgcgcag atcggcatat tcggcaatgt gttgccccca gatcccagcg gcattaacca
    11161 cgacaggtgc atgaagggcc tgagtttcgc cggtgagatg gttacgtaca cgaacaccgc
    11221 acaccgtcgc gccttcacga atcagccccg tgacttcatg agcggtaagg ataacggcac
    11281 cgtgttcttt ggcatccagc atgtttgctg cggtcagacg aaatggatca acggtgccat
    11341 ccggaacttt caccgcgcca atcagtgccg ggttaacggc aggttcgata atgcgcgctt
    11401 gctgcgggtc tatagcttct gcgctgatcc ctgcttcttc gcaggcgcga ataaaagtgg
    11461 cctggaagga gaggtcatct tccggcaggg tgataaacag gccgttggtt ggttcaacgc
    11521 agtgacgtgc aatgcgtttc aggatctggt tttcactaat gcattcgcgg gccgattccg
    11581 catcggttac cgcatagcgc gcaccgctgt gcagcaggcc gtggttacgc ccggtggcac
    11641 cggttgcgat gtcgtggcgc tcaaccaaaa tcacgcgcag cccgcgcagg gcacagtcgc
    11701 gggcaatccc ggctcccgtt gcgccgccgc caatgataat cacgtcactt gattgcgagt
    11761 cgcgagtttt cattgttatc cctctgaagt tcgtttttta ccatttagcc atagtaaaaa
    11821 catgaattgt ttgatttcgc gcatattcgc tcataattcg aaagtgaaac gtgatttcat
    11881 gcgtcatttt gaacattttg taaatcttat ttaataatgt gtgcggcaat tcacatttaa
    11941 tttatgaatg ttttcttaac atcgcggcaa ctcaagaaac ggcaggttct ctcactgaat
    12001 caggctgtta atcataaata agaccacggg ccacggaggc tatcaatgtt gagtattttt
    12061 aaaccagcgc cacacaaagc gcgcttacct gccgcggaga tcgatccgac ttatcgtcga
    12121 ttgcgctggc aaattttcct ggggatattc tttggctatg cggcttacta tttggttcgt
    12181 aagaactttg cgcttgctat gccttatctg gttgagcagg gattctcacg cggtgattta
    12241 ggttttgccc tttcggggat ctcgattgct tatggatttt cgaaattcat catgggttcg
    12301 gtatcggatc gctcgaatcc gcgcgttttc ctgcccgcag gtttgattct ggcggcggca
    12361 gtgatgttgt ttatgggctt tgtgccatgg gcgacgtcga gcattgcggt gatgtttgta
    12421 ctgttgttcc tctgcggttg gttccagggg atggggtggc cgccgtgtgg tcgtactatg
    12481 gtgcactggt ggtcgcagaa agaacgtggc ggcattgtgt cagtgtggaa ctgtgcgcac
    12541 aacgtcggtg gtggtattcc gccgctgctg ttcctgctgg ggatggcctg gttcaatgac
    12601 tggcatgcgg cgctctatat gcctgctttc tgcgccattc tggtggcatt attcgccttt
    12661 gcgatgatgc gcgatacccc gcaatcctgt ggcttgccgc cgatcgaaga gtacaaaaat
    12721 gattatccgg acgactataa cgaaaaagcg gaacaggagc tgacggcgaa gcaaatcttc
    12781 atgcagtacg tactgccgaa caaactgctg tggtatatcg ccatcgccaa cgtgttcgtt
    12841 tatctgctgc gttacggcat cctcgactgg tcaccgactt atctgaaaga ggttaagcat
    12901 ttcgcgctag ataaatcctc ctgggcctac ttcctttatg aatatgcagg tattccgggc
    12961 actctgctgt gcggctggat gtcggataaa gtcttccgtg gcaaccgtgg ggcaaccggc
    13021 gttttcttta tgacactggt gaccatcgcg actatcgttt actggatgaa cccggcaggt
    13081 aacccaaccg tcgatatgat ttgtatgatt gttatcggct tcctgatcta cggtcctgtg
    13141 atgctgatcg gtctgcatgc gctggaactg gcaccgaaaa aagcggcagg tacggcagcg
    13201 ggctttaccg ggctgtttgg ttacctgggc ggttcggtgg cggcgagcgc gattgttggc
    13261 tacaccgtgg acttcttcgg ctgggatggc ggctttatgg taatgattgg cggcagcatt
    13321 ctggcggtta tcttgttgat tgttgtgatg attggcgaaa aacgtcgcca tgaacaatta
    13381 ctgcaagaac gcaacggagg ctaatggcat gaaattgacg ctgaaaaacc ttagcatggc
    13441 gatcatgatg agcactatag tcatgggaag cagtgcaatg gcggcggaca gcaacgaaaa
    13501 aatagtcatc gcccatcgcg gtgccagtgg atatttgccg gagcatacgc tgccagcaaa
    13561 agcgatggcg tatgcgcagg gagcggatta tctggaacag gatttggtga tgaccaaaga
    13621 cgacaatctg gttgttctgc atgaccatta cctcgatcgt gttactgatg ttgccgatcg
    13681 tttcccggat cgggcgcgca aagacggtcg ttactacgcg atagatttca cgctggatga
    13741 aattaagtcg ttgaaattta ccgaaggttt cgatattgaa aacggtaaaa aagtgcagac
    13801 ttatccgggg cgtttcccaa tgggtaagtc cgacttccgg gtgcacacct ttgaagaaga
    13861 gattgaattt gttcaggggt taaatcactc taccgggaaa aatatcggta tttatccaga
    13921 aatcaaagcg ccgtggttcc atcatcagga agggaaggat attgcggcaa aaacgctgga
    13981 agtgctgaag aaatatggtt acaccggtaa agacgataaa gtttatttgc aatgttttga
    14041 tgctgatgag ctgaagcgta ttaagaatga gctggaaccc aaaatgggca tggagctcaa
    14101 tctggtacag ctgattgcct ataccgactg gaatgaaacg cagcagaaac agccggatgg
    14161 aagctgggtt aattacaact acgactggat gtttaagccg ggtgccatga aacaggtggc
    14221 ggaatatgca gatggtattg gtccggatta ccatatgttg attgaggaga catcgcagcc
    14281 gggtaatatc aaactcactg gcatggtgca agatgctcag cagaataaac tggtagtgca
    14341 tccttatacc gtgcggtcag ataaactgcc tgaatacact cctgatgtga atcagttata
    14401 tgatgctctg tataacaaag cgggtgtaaa tgggctgttt actgatttcc ctgataaggc
    14461 agtaaaattt cttaataaag agtaatgtta ctgcaggatg gcgttcatgc gccatcctgt
    14521 ctcatatcaa atttttccaa tcgccactaa ttgttccatg cacatttgta gtaaaaacag
    14581 tggactgcct tctaccggct tttctttagc cagcaacgaa atctgtcgat agaaagttgg
    14641 ttcgagagga acggaacaca attcacctgc aatgcttttc agcgttaact ctggttgtaa
    14701 ggcgatgcct aatccctgtc gaataaaatt catcgctgta tccgcctgat taaattcaca
    14761 ttttatctgc tgggcgcact attagtggta gtggctggtg gaatctatgc gctgcaaatg
    14821 aagggtaaaa gcggtgtcaa gctagtagtg gcaaaagaaa ttcattaata cgacacgttt
    14881 cattaagatt ttcctcaggt aaccacctat agtcattgtc gttaataaaa atgacaggcg
    14941 atagggtatg gcagtttcag caaagtacga cgaatttaat cactggtggg caacagaggg
    15001 cgactgggtt gaagagccta actatcgccg taatggtatg agcggggtgc aatgcgtcga
    15061 gcgcaacggc aaaaagctgt atgtaaagcg catgacgcat catctgtttc attccgtacg
    15121 ttatccgttc ggccgaccaa cgattgtccg tgaggttgcg gtaattaaag aactggaacg
    15181 ggccggtgtc atcgtgccga agatcgtttt tggtgaagcg gtgaaaattg agggtgaatg
    15241 gcgagcgttg ctggtgactg aagatatggc ggggttcatc agcattgctg actggtatgc
    15301 ccagcatgca gtatcgcctt attctgacga agtacggcaa gccatgttga aagcagtggc
    15361 gctggcgttt aagaaaatgc atagcattaa tcgtcagcat ggctgttgtt atgttcgcca
    15421 tatctatgtg aaaacagaag gtaatgcaga agctggtttt cttgacctgg agaaaagtcg
    15481 tcgccgcttg cgtcgcgata aagcgattaa tcatgacttc cgccagctgg aaaaatatct
    15541 ggagccaatc cccaaagcgg actgggagca ggtgaaagcg tattactacg ccatgtaatc
    15601 gttgtaggcc agataagacg cataagcgtt gtatctggca ctacaaccaa ttcacatctc
    15661 gatttcaata tcgccttttg cccggcaaca acagggcaaa atttcccccg gctgaataaa
    15721 ggctaacggt tcggcaatcc agtcaacttg acctgcaacc aggcgtgtgc gacaggagcc
    15781 gcagtaacct tcgcgacact ggtactcaac cgccacattg tgggattcca gcgccgccag
    15841 aagggaaggg tgttcatcct ggcacagcag ttgtgtgcca gtgatgcgca gggtaacgcg
    15901 ggccatcaga gctggaagtt actcaaatcg tcggtgtcca cttccgagtc aatctgcccg
    15961 accagataag aactgacttc cacttcctgc ggagcaacct gcacgttatc agacaccagc
    16021 caagtgttga tccacgggat cgggttggag cgcgtctgga acggcagatc caaaccgact
    16081 gcctgcatac ggatattggt gatgtattca acgtactggc agagaatgtc tttattcaga
    16141 ccaatcatcg aaccgtcgcg gaacagataa tccgcccagt ctttctcctg ttgagctgcc
    16201 tgaacaaaca ggtcatagca ctcctgctta cactcttcgg caatttccgc catctcagga
    16261 tcgtccgcgc cgctgcgcag cagattcagc atatgctggg tgccggtcag gtgcagggct
    16321 tcgtcgcggg caatcaggcg aataattttg gcgttgcctt ccatcaattc gcgttctgca
    16381 aatgcgaagg aacaagcaaa gctgacgtag aaacgaatcg cttccagcgc gttaacgctc
    16441 atcaggcaga gatacagttt tttcttcagc tcgcgcaggc taacggtcac agttttaccg
    16501 ttaacggtgt gggtaccttc gcccagcaga tgccagtagc tggtcatttc gatcagctca
    16561 tcgtaatagc tggagatccc ttccgcacgt ttctggatct gctcgttggt gacgatatcg
    16621 tcaaacacaa cagacggatc gttaacgata ttacgaatga tatgagtata ggaacgggaa
    16681 tgaatcgttt ctgagaacgc ccaggtttcg acccaggttt ccagttccgg aatagaaata
    16741 agcggcaata gcgccacgtt cgggctacga ccctgaatgg aatccagcag cgtctgatat
    16801 ttcaggttgc tgataaagat gtgtttttcg tgctccggca gcgcctggta atctatacgg
    16861 tcgcgggaga cgtcaacttc ttccggacgc cagaagaaag agagctgctt ttcgatcagc
    16921 ttttcgaaga tgtcatattt ttgctgatcg tagcgagcca cgttgaccgg ctgaccaaag
    16981 aacatcggtt ctttgagctg atcatttttc gtctgtgaaa aggtggtata tgccatgagt
    17041 gtgtcctgtt gggagtttaa tgccggataa ggcattttac gccgcatcct gtgcctgatg
    17101 cgacgctggc gcgtcttatc aggcctacaa atccgagccg taggccggat aaggcgttca
    17161 cgctgcatcc ggcacccgga gcctgatgcg acgctggcgc gtcttatcag gcctacaaac
    17221 cgagccgtag gccggataag gcgtttacgc cgcatccggc atctcaatat cagatcttac
    17281 atgcgccgct ttcgcagcca tcgtcctgga ttgacggcac cagatcgtct tgtgcgtctt
    17341 cagcgccgtc acgggtgttc tgataataca gtgttttgac cccgaatttg taggcggtga
    17401 gcaggtcttt cagcaactgc tgcatcggca cttttcctga cgggaagcgt gacggatcgt
    17461 agttggtgtt ggcagagatc gactgatcga taaatttctg catgataccc accagttgca
    17521 gataaccatc gttacccggc atttcccaca gcagctcata ggcgtcgtgc aggtgctcgt
    17581 agtccggcac cacctggcgc aaaataccgt ctttcgacgc tttgatgctg acgtaaccgc
    17641 gcggcggttc aataccgtta gtggcgttag agatctgcga agaagtctcg gacggcatca
    17701 gagcagaaag cgtggagtta cgcagaccgt gcgttttgat tgactcacgc agagcttccc
    17761 agtcgtaatg cagcggctca ttagcgatgg tatccagatc tttcttatag gtatcgatcg
    17821 gcaggatccc tttcgcgtaa gtggtttcgt taaaccacgg gcacgcgcct tgctctttcg
    17881 ccagctcatt agaggctttc agcaggtaat actgaatggc ttcgaaggtt ttatgcgtca
    17941 ggttgttggc gctgccgtcg gagtatcgtt taccgtgctt cgccaggtag taagcgaagt
    18001 tgatcacacc aatacccagc gtacgacgac ccatcgctcc acgtttggcg gccgggatcg
    18061 ggtaatcctg ataatccagc agcgcgtcaa gtgcacgaac cgccagaatt gccagctctt
    18121 ccagttcatc caggttatta attgcgccca ggttgaaagc agacagcgta cacagcgcga
    18181 tttcaccgtt ctcgtcgttg acgtcgttca gcggtttggt cggcagggct atctccaggc
    18241 acaggttaga ctgacgcact ggcgcgatgg ccggatcaaa cgggctatgg gtattgcagt
    18301 ggtcaacgtt ctgaatatag atacgaccgg tagacgcacg ttcctgcatc atcagcgaga
    18361 acagctcaac ggctttcaca cgctgcttgc ggatgctgtc gtctttctca tatttggtat
    18421 acagacgttc aaactcttcc tgatcggcga agaacgcgtc gtacagcccc ggtacgtcgg
    18481 acgggctgaa cagggtgata tcttcacctt tcagcagacg ggtatacatc agtttgttga
    18541 tttgtacccc gtagtccata tgacgcacgc ggttgccttc cacaccacgg ttgtttttca
    18601 acaccagcag gctttccact tccagatgcc acatcgggta gaacagcgtt gccgcaccgc
    18661 cgcgcacacc gccctgagag caggatttca ccgctgtctg gaaatgtttg tagaacggaa
    18721 tgcagccggt atggaacgct tcaccaccgc gaatcgggct acccagcgca cgaatacgcc
    18781 cggcgttgat gccgatcccg gcacgctggg aaacgtattt aacaatcgcg ctggaggtgg
    18841 cgttgatgga atccaggctg tcaccgcact cgatcagtac gcaggagctg aactgacgag
    18901 tcggggtacg cacgccggac atgattggcg tcggcagcga aattttaaat gtggaaaccg
    18961 cgtcgtaaaa acgcttcaca tattgcaggc gcgtttcacg cgggtagttc gagaacaagc
    19021 acgcggcaac tagaatataa aggaactggg cgctctcata gatttcgccg gtcacgcggt
    19081 tctgtaccag atatttgcct tccagctgct taacggcagc ataagagaag gtcatatcac
    19141 ggtcgtgatc gataaaggtg tccatctgct tgaactcttc ttccgtgtag tcttccagca
    19201 gatgattatc gtatttgccc atctcgacca ttttcaccac gtggtcgtac agcgcaggcg
    19261 gctcaaactg gccgtaggct tttttacgca ggtggaagat cgccaggcgc gcggcgagat
    19321 actgataatc cggcgcatca cgggagatca ggtctgcggc agccttgata atggtttcgt
    19381 ggatgtcaga ggtcttgata ccgtcataaa actgaatgtg ggagcgcagc tcgacctggg
    19441 aaatcgaaac gttatgcagt ccttctgccg cccaatccag aacgcgatgg attttgtcga
    19501 gattgatgcg ctctgtgcta ccgtcgcgct ttgtcaccag cagattctga ttcatgtatg
    19561 tcgtacctgt ttttggaatt ctttccgcaa tagtttcatg cagactacct gtagtacggg
    19621 aagctgctta gaacactata tatagggggt atgtttggga ttcactgcaa gatagtgtga
    19681 aaatgaccct cttgcaagtg cataactttg tggataactc aggaaggaaa aagtggcttt
    19741 cgcgcacctt aggtcagaca aggtgtccgg gaaagtcaat gggaagagaa aaatttgtta
    19801 aaaataactg ttcggcgatt tcttgaacgg cataataggt tagataaatt gatatagatg
    19861 gtttattaat ctttttgcta atgat
//
LOCUS       DAPHKZ010000081        19857 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.081, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000081 DAPHKZ010000000
VERSION     DAPHKZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19857
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.081"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(78..518)
                     /locus_tag="RH288_003034"
     CDS             complement(78..518)
                     /locus_tag="RH288_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDV4032070.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAATVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVG
                     RFVPTLILVMMLIDLGAFVGTQGENKYGKDTQDVKYKADNKSSN"
     gene            619..1218
                     /locus_tag="RH288_003035"
     CDS             619..1218
                     /locus_tag="RH288_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HDV4032071.1"
                     /translation="MKPGCTLFFLLCSALTVTTAAHAQTPDTATTAPYLLAGAPTFDL
                     SISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRAASKINENLYASTALERGTLKIK
                     SIQMTWLPIQGPEQKAAKAKAQEYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
                     TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK"
     gene            1326..2093
                     /gene="tpiA"
                     /locus_tag="RH288_003036"
     CDS             1326..2093
                     /gene="tpiA"
                     /locus_tag="RH288_003036"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDV4032072.1"
                     /translation="MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPE
                     MYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA"
     gene            complement(2148..2903)
                     /gene="cdh"
                     /locus_tag="RH288_003037"
     CDS             complement(2148..2903)
                     /gene="cdh"
                     /locus_tag="RH288_003037"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HDV4032073.1"
                     /translation="MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLP
                     NQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFW
                     LAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
                     ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGRYGLAMVRQS
                     DNSFVLLATQRNLLTLNRASAEEIQDHQCEILR"
     gene            complement(3010..3999)
                     /gene="sbp"
                     /locus_tag="RH288_003038"
     CDS             complement(3010..3999)
                     /gene="sbp"
                     /locus_tag="RH288_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter
                     substrate-binding protein Sbp"
                     /protein_id="HDV4032074.1"
                     /translation="MNKWGVGLTFLLAATSVMAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFVRALYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     ANELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAK
                     NYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANGCTFDQISKR"
     gene            complement(4319..5281)
                     /gene="pfkA"
                     /locus_tag="RH288_003039"
     CDS             complement(4319..5281)
                     /gene="pfkA"
                     /locus_tag="RH288_003039"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDV4032075.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
                     HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     gene            complement(5462..6364)
                     /gene="fieF"
                     /locus_tag="RH288_003040"
     CDS             complement(5462..6364)
                     /gene="fieF"
                     /locus_tag="RH288_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312867.1"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HDV4032076.1"
                     /translation="MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALV
                     DSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGI
                     QHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
                     NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEI
                     IDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFP
                     GSDVIIHQDPCSVVPREGKRSMLS"
     gene            complement(6513..7013)
                     /gene="cpxP"
                     /locus_tag="RH288_003041"
     CDS             complement(6513..7013)
                     /gene="cpxP"
                     /locus_tag="RH288_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HDV4032077.1"
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKM
                     ANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
                     SNSRSQ"
     gene            7163..7861
                     /gene="cpxR"
                     /locus_tag="RH288_003042"
     CDS             7163..7861
                     /gene="cpxR"
                     /locus_tag="RH288_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HDV4032078.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            7858..9231
                     /gene="cpxA"
                     /locus_tag="RH288_003043"
     CDS             7858..9231
                     /gene="cpxA"
                     /locus_tag="RH288_003043"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HDV4032079.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTV
                     NFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIW
                     LPLYKRS"
     gene            complement(9337..10011)
                     /gene="yiiM"
                     /locus_tag="RH288_003044"
     CDS             complement(9337..10011)
                     /gene="yiiM"
                     /locus_tag="RH288_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HDV4032080.1"
                     /translation="MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTELGLEGDEQ
                     AEKKVHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYMGD
                     IFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGKVSADAPL
                     ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFS
                     RRLWGK"
     gene            complement(10160..11143)
                     /gene="kdgT"
                     /locus_tag="RH288_003045"
     CDS             complement(10160..11143)
                     /gene="kdgT"
                     /locus_tag="RH288_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HDV4032081.1"
                     /translation="MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMI
                     TGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVE
                     VGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
                     AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTV
                     IAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEM
                     VPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIDILGTVK"
     gene            complement(11404..12024)
                     /gene="sodA"
                     /locus_tag="RH288_003046"
     CDS             complement(11404..12024)
                     /gene="sodA"
                     /locus_tag="RH288_003046"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HDV4032082.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALE
                     SLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAASRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPIMGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            12309..13343
                     /gene="rhaT"
                     /locus_tag="RH288_003047"
     CDS             12309..13343
                     /gene="rhaT"
                     /locus_tag="RH288_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HDV4032083.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIV
                     SWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLISTEGGRMTLLGVLVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     VIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKSLIIHNVLLSTLGGLMWYLQFFFY
                     AWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVA
                     ANIVGIGMAN"
     gene            complement(13340..14206)
                     /gene="rhaR"
                     /locus_tag="RH288_003048"
     CDS             complement(13340..14206)
                     /gene="rhaR"
                     /locus_tag="RH288_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HDV4032084.1"
                     /translation="MAEVATVAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDF
                     CELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKL
                     NLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVIGQLEHESSQHVPFANEMAELLFGQ
                     LVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQ
                     FRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMT
                     PSQWRHLNSQKD"
     gene            complement(14262..15098)
                     /gene="rhaS"
                     /locus_tag="RH288_003049"
     CDS             complement(14262..15098)
                     /gene="rhaS"
                     /locus_tag="RH288_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HDV4032085.1"
                     /translation="MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLL
                     PQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKS
                     SLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQR
                     YLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGF
                     LQ"
     gene            15386..16855
                     /gene="rhaB"
                     /locus_tag="RH288_003050"
     CDS             15386..16855
                     /gene="rhaB"
                     /locus_tag="RH288_003050"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDV4032086.1"
                     /translation="MTFRNCIAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHS
                     QNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAY
                     RDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLM
                     PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIG
                     HWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLQEQQINDLPALISATQALPACRFIINP
                     NDDRFINPETMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGE
                     DFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA"
     gene            16852..18111
                     /gene="rhaA"
                     /locus_tag="RH288_003051"
     CDS             16852..18111
                     /gene="rhaA"
                     /locus_tag="RH288_003051"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDV4032087.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESD
                     TPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNP
                     AHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINR
                     IAAWVIGTRNMKKALLRALLEPTAELRKLEEAGDYTARLALLEEQKSLPWQAVWEMYC
                     QRHDTPAGSEWLESVRAYEKEILSRRG"
     gene            18562..19386
                     /gene="rhaD"
                     /locus_tag="RH288_003052"
     CDS             18562..19386
                     /gene="rhaD"
                     /locus_tag="RH288_003052"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDV4032088.1"
                     /translation="MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAP
                     YHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGY
                     HILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAV
                     FTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLALWPFHGVFGSG
                     PTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL"
     gene            19396..19710
                     /gene="rhaM"
                     /locus_tag="RH288_003053"
     CDS             19396..19710
                     /gene="rhaM"
                     /locus_tag="RH288_003053"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDV4032089.1"
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIY
                     LDKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFY
                     LP"
BASE COUNT         4928 a         5214 c         5012 g         4703 t
ORIGIN      
        1 gattttccgg gtattgtcat ttgcatcgtg gaaataacaa tcccggaaaa aaatagcagt
       61 aagagatata ttaaaggtta attacttgat ttattgtcgg ctttatactt cacatcctga
      121 gtatctttac catatttatt ttcgccttgt gtgccaacaa acgcaccaag atcgataagc
      181 atcatcacca gaatcaacgt cgggacaaaa cgccccaccg cccattgcca gacacccggt
      241 aaaatcgccc agttacccgc cagcagcatc cacgccacaa tcatcagaaa tgcccatgcg
      301 ccggaacgcc cgcgatcatg caagcgctta acagttgctg ccgctgttgg ccagagcaag
      361 cacacaaggc aaaacgccgc ggtctgaata tcgagtagat tcttacccgc cagtgagaaa
      421 agcaccagca tgcctgcgaa ccacaggcct atccaaatcc agaaatcacg gcgtccaata
      481 cgccctttaa atgagaataa ccattgctgt atggtcatgt aagttccttg atggttgtct
      541 tttccaggat tctacccttt tgacaagggc gacagatatc gttttaatcg gagccagtca
      601 taacaaaagg tactgtcaat gaagccaggg tgtacgctgt tttttctctt atgttctgca
      661 ttaaccgtta caacagcggc gcatgcacaa acaccagata cggcaacgac cgcgccttat
      721 ctgctggctg gagcccctac tttcgatctc tccatcagcc agtttcgaga agactttaac
      781 agccagaatc ccagcctgcc actgaacgaa tttcgtgcca tcgacagcag tcccgacaaa
      841 gccaatctca ctcgtgctgc aagtaaaatt aatgagaact tgtatgcttc tacagcgctg
      901 gagcgcggta ccttaaaaat caaaagcatt caaatgacct ggctacccat ccaggggcca
      961 gagcaaaaag ccgcgaaagc gaaagctcag gaatacatgg cagcggtgat ccgcacactc
     1021 accccattaa tgaccaaaac acaaagccag aaaaaactgc agtcgctact aacggcgggg
     1081 aaaaacaaac gttattacac cgagacagaa ggtgcactgc gttatgttgt cgcggacaac
     1141 ggcgaaaagg ggctgacctt cgctgttgaa ccgattaagc tggcgctatc tgaatcgctt
     1201 gaaggtttga ataaatgaca aaaagcaaag cctttgtgcc gatgaatctc tatactgttt
     1261 cacagacctg ctgccctgcg gggcggccat cttcctttat tcgcttataa gcgtggagaa
     1321 ttaaaatgcg acatccttta gtgatgggta actggaaact gaacggcagc cgccacatgg
     1381 ttcacgagct ggtttctaac ctgcgtaaag agctggcagg tgttgctggc tgtgcggttg
     1441 caatcgcacc accggaaatg tatatcgata tggcgaagcg cgaagctgaa ggcagccaca
     1501 tcatgctggg tgcgcaaaac gtggacctga acctgtccgg cgcattcacc ggtgaaacct
     1561 ctgctgctat gctgaaagac atcggcgcac agtacatcat catcggtcac tctgaacgtc
     1621 gtacttacca caaagaatct gacgaactga tcgcgaaaaa attcgcggtg ctgaaagagc
     1681 agggcctgac tccggttctg tgcatcggtg aaaccgaagc tgaaaatgaa gcgggcaaaa
     1741 ctgaagaagt ttgcgcacgt cagatcgacg cggtactgaa aactcagggt gctgcggcat
     1801 tcgaaggtgc ggttatcgct tacgaacctg tatgggcaat cggtactggc aaatctgcaa
     1861 ctccggctca ggcacaggct gttcacaaat tcatccgtga ccacatcgct aaagttgacg
     1921 ctaacatcgc tgaacaagtg atcattcagt acggcggctc tgtaaacgcg tctaacgctg
     1981 cagaactgtt tgctcagccg gatatcgacg gcgcgctggt tggtggtgct tctctgaaag
     2041 ctgacgcctt cgcagtaatc gttaaagctg cagaagcggc taaacaggct taagtctgac
     2101 aggtgccgga tttcatatcc ggcacttact ttccttaact cttcgcctta acgcaaaatc
     2161 tcacactgat gatcctgaat ttcctcggct gaagcacggt taagcgtcag tagatttcgt
     2221 tgtgtcgcca gcaatacaaa tgagttatca ctctgccgta ccatcgccag cccgtagcgt
     2281 cccatatgtt cccgcgcctc aggtacttct tctgccagca tcataaatgg gctgcgttgt
     2341 accagttcgc tttccgttac ccgacgcgcc aggtattcat gcccgcgcaa accacctggc
     2401 agtggcaacc agcggctgct gatgttcgcc agattgttat ccagctgttc gcgcacatca
     2461 ggacgaatac aagagatatg aatatgaaaa tggttttgcg tacgcccggt gcgggagttg
     2521 atcgccaaag aaaccgcgcg atcgggaacc ggctggccgt attttttgct cataaaatca
     2581 cgcgcctgcc aagccaacca aaagaagttc ggcgttgaag gatcggtcaa caaaggactt
     2641 tcagtaccgt taatacgata cgttggcatc aacagatatt gcagtgggcc attaagatct
     2701 tttaaaacca cgtatccggc attgggtttg acttccgcac atggcgaagg attttgattt
     2761 tgctgctgat tgggcaaaca ttcctcaagg acaatcttac gtaatgtatc cgactcttca
     2821 ccggttaatt tccagtaacc aataccggca gccacaacgg cgataactat catcaccaaa
     2881 aaaagaagac ccgctttttt catctttttt tccctgtacc tcaaagagat gcaagggtaa
     2941 cgcaaaatcg tgacaaataa aaaacccggt cgcgagaaac caccgggttt gataattatc
     3001 ctggggaaat cagcgtttgc tgatctgatc gaacgtacag ccgttagcaa aatgctcttt
     3061 ttgcgctttc gtccagccgc cgaactcttc atcaatggtg aataacttca gctttggaaa
     3121 cgcattttcg tactttttcg ccacctcagc gtcgcgcgga cggtagtagt ttttcgcggc
     3181 aatttcctga ccttctggcg agtagagata tttcaggtag gcttccgcca cctctttagt
     3241 accttttttc tcgaccactt tatcgaccac cgacacggtt ggctctgcga ggatagactc
     3301 actcggcgtg acgatttcga atttatcttt ccccagttca ttcgctgcca gcagagcttc
     3361 gttttcccag gcaatcagta catcgccaat tccgcgctcg acaaaagtgt tagtggagcc
     3421 acgcgcacca gaatccagaa cttcgacgtt tttatacagt gcccgaacaa aatcctgtgc
     3481 ttttgcctga tcgttgttgt tgtgatgcag cgcgtagccc caggctgcca ggtagttcca
     3541 gcgcgcgcca ccagagcttt tcggattagg cgtgatcacc gaaacacccg gtttaatcag
     3601 atcgttccag tcatggatct gcttcggatt tcccttacgt accaggaaaa caatggtgga
     3661 agtgtacggt gcggagttat ccggcagacg tttgatccac tctttatcaa tccgcccgcg
     3721 ttccgcaatt gcgtccacgt cataggccag agccagcgtg acaacatcag cttcaatacc
     3781 gttgattacc gacgtcgctt gtttacctga gccaccgtgt gactgacgaa tcaccacgtt
     3841 atcaccagtt tgctgtttcc agtgggcgct gaatgccttg ttgtactgtt cgtacaattc
     3901 gcgcgttgga tcatatgaaa cgttaagaag ctgaatatcc tttgccataa cgctggttgc
     3961 cgccagcaaa aatgttaacc ctacgcccca cttgttcatc gcccgactct cttatgttgt
     4021 gttgtgatga gcaaagcgtg ccagaaggtt aaccaaacat taaagaataa aaaaagattg
     4081 gctataactt gcgggtatat gttgagggat taaaaaggcg gaagaaatcc gcctcatatt
     4141 gctgacaaag tgcgctttgt ccatgccgga tgcggcgcga acgccttatc cggcctacaa
     4201 aagtttgcaa attcaataaa ttgcagaatt catgtaggcc tgataagcga agcgcatcag
     4261 gcatttttgc ttctgtcatc ggtttcaggg taaaggaatc tgcctttttc cgaaatcatt
     4321 aatacagttt tttcgcgcag tccagccagt cacctttgaa cggacgcttc atgttttcga
     4381 tagcgtcgat gatgtcgtgg tgaaccagct gttcgttctg gatacctaca caacgaccgc
     4441 cgtaacctgc cagcagcaga tcgatagcgt aagcgcccat acgggaagcc agaatacggt
     4501 cgtaaggcac cggagaacca ccgcgctgga tgtggcccag cacagttgcg cgggtttcac
     4561 gaccggtttc tttctcgatg aaatgcgcca gttcgtcaac atcacacata tgttcggtaa
     4621 tcgccacgat cgcgtgtttt ttacctttcg cgatacccgc tttgatttcg tttaccaggt
     4681 cttcacggct gaattcaact tccggaacca caacgaattc acagccaccg gcaatggccg
     4741 cagccaacgt cagatctcca caataacggc ccatcacttc caccacggaa atacgctggt
     4801 gagaagaaga ggtgtcacgc agacggtcga tcgcttctac aacggtgctc agcgcagtga
     4861 agaaaccgat agtgtagtca gtgcctttga tgtcgttgtc gatagtgccc ggcagaccga
     4921 tgcacgggaa gcccatttcg gtcagacgca ttgcacccat gtaggaaccg tcaccgccga
     4981 taaccaccag cgcgtcgata ccacgttttt tcaggttttc gatagccacg gcgcggatgt
     5041 tctcgtcgcg gaattccggg aaacgcgcag aaccgaggaa cgtaccgcca cggttgatca
     5101 tgtcagacac gctgtaacgg tctagctgta ccatacggtc ttcatacaga cccagatagc
     5161 cgtcataaat acccattact tccagacctt ctgtcagcgc agaacgaaca accccgcgaa
     5221 ttgcggcgtt catgcctggc gcatcaccgc cgcttgtcaa cacaccgatt ttcttaatca
     5281 tgactacctc tgaactttgg aatgcaaaat gaaatctgtt gccggaagtc ttcttgcaca
     5341 tcgaagtgat ccaacgaatg tgcaaatagt ataacaatta cttcctgctg aattgattca
     5401 ggtcaggcca aatggcggta ttttatacac aaaatgcggg tctggctctc ttttatactg
     5461 attatgaaag catagaccgt ttaccctccc tgggtacgac ggaacagggg tcctgatgga
     5521 taattacatc cgatcccgga aaacgccgta aaatagcctg ctctacctga tccgccacca
     5581 tatgtgcctg aaccaaaggc agagagtctt ccatttccaa atgaatctga ataaagcggg
     5641 tcggccctga ctgccgcgtg cgaagatcgt gagcgccgct aacacccggc caggaagtca
     5701 cgatatcaat aatttcttgc cgttcctcat caggcaatgc gcgatccagt aatgactgta
     5761 ccgcctcata tcccatgcgt aacgcgctat ataaaatata gatgccgatt cccaatgcaa
     5821 acagagcatc ggcgcgatgc cagccgtacc aggacaaccc cagcgccagc agaattgcgc
     5881 cgttcatcat aacatcagac tggtaatgta gcatatcagc ccgcaccgcc tggctttgcg
     5941 tccgccgcac cacccaacgc tgaaacgaga caaggataat cgtacaaatt agcgccacaa
     6001 ttgtcacgat aaccccgacg cctggatctg tcatcggtgt tggagatatc agatgttgaa
     6061 tacccgtcaa aaacaggaat agtgccgaac cggagataaa catactttgc gccagcgccg
     6121 cgagggactc agctttaccg tgaccaaacg agtgattatc gtcggcaggt tgcagggaat
     6181 atcgcaccac caataaattc gtcaacgacg cgccgatatc caccagcgaa tccaccagcg
     6241 cggcgagaat actcaccgac ccggtatacc accatgcaaa aattttaatc agcaatagca
     6301 gcgaagccat cgccgtcgca gcaatcgccg cccgactgac cagccgtcca taagattgat
     6361 tcataaatac tcccgctatc aactgacgct agtataacgg aagcaaatca tctgcaatgc
     6421 attaagcagc aggcaaattg aggataaaaa aaacccccac agcatgtggg ggaagacagg
     6481 gatggtgtct atggcaagga aaacagggtt tactactggg aacgtgagtt gctactactc
     6541 aatagcttca acgatgaact tttttgccat tgcgtcacgt cacgcaactg ctccattcgt
     6601 tgttgatgtt tctcgtttaa aaccgcttgc tgctccggcg ttaacaggcg atacatttgg
     6661 ttgcggactt ttgccatctc aacctgacga gcaatttgct cattcgccat tttttctgcc
     6721 tgtgcgcgca cagcgttttc atcaaaattt tctgcggtga caaggcgatg cattgtctcc
     6781 agttcgctaa cattaacagg aggctgttcg tgccgggcct gttgcataag atctcgcatc
     6841 tgctgacgct gatgttcggt taaacttatg ccgtcgaaca tatggctctg cgtactgcgc
     6901 tgcgtaagtt cttcacccgg atgccagtta tcgcctgaac cgacttcagc agcgtggctt
     6961 aatgaactga ctgccagcgt tgaggccatg acggcagcgg taactatgcg catcatttgc
     7021 tcccaaaatc tttctgtcgc gattcaacga tagagagttt acgattcagg ctgcaaacat
     7081 gcgtcagggg gtgtaaaaca acgtaaagtc atggattagc gacgtctgat gacgtaattt
     7141 ctgcctcgga ggtatttaaa caatgaataa aatcctgtta gttgatgatg accgagagct
     7201 gacttcccta ttaaaggagc tgctcgagat ggaaggcttc aacgtgattg ttgcccacga
     7261 tggggaacag gcgcttgatc ttctggacga cagcattgat ttacttttgc ttgacgtaat
     7321 gatgccgaag aaaaatggta tcgacacatt aaaagcactt cgccagacac accagacgcc
     7381 tgtcattatg ttgacggcgc gcggcagtga acttgatcgc gttctcggcc ttgagctggg
     7441 cgcagatgac tatctcccga aaccgtttaa tgatcgtgag ctggtggcac gtattcgcgc
     7501 gatcctgcgc cgttcgcact ggagcgagca acagcaaaac aacgacaacg gttcaccgac
     7561 actggaagtt gatgccttag tgctgaatcc aggccgtcag gaagccagct tcgacgggca
     7621 aacgctggag ttaaccggta ctgagtttac cctgctctat ttgctggcac agcatctggg
     7681 tcaggtggtt tcccgtgaac atttaagcca ggaagtgttg ggcaaacgcc tgacgccttt
     7741 cgaccgcgct attgatatgc acatttccaa cctgcgtcgt aaactgccgg atcgtaaaga
     7801 tggtcacccg tggtttaaaa ccttgcgtgg tcgcggctat ctgatggttt ctgcttcatg
     7861 ataggcagct taaccgcgcg catcttcgcc atcttctggc tgacgctggc gctggtgttg
     7921 atgttggttt tgatgttacc caagctcgat tcacgccaga tgaccgagct tctggatagc
     7981 gaacagcgtc aggggctgat gattgagcag catgtcgaag cggagctggc gaacgatccg
     8041 cccaacgatt taatgtggtg gcggcgtctg ttccgggcga ttgataagtg ggcaccgcca
     8101 ggacagcgtt tgttattggt gaccaccgaa ggccgcgtga tcggcgctga acgcagcgaa
     8161 atgcagatca ttcgtaactt tattggtcag gccgataacg ccgatcatcc gcagaagaaa
     8221 aagtatggcc gcgtggaact ggtcggtccg ttctccgtgc gtgatggcga agataattac
     8281 caactttatc tgattcgtcc ggccagcagt tctcaatccg atttcattaa cttactgttt
     8341 gaccgcccgc tattactgct gattgtcacc atgttggtca gtacgccgct gctgttgtgg
     8401 ttggcctgga gtctggcaaa accggcgcgt aagctgaaaa acgctgccga tgaagttgcc
     8461 cagggaaact tacgccagca cccggaactg gaagcggggc cacaggaatt ccttgccgca
     8521 ggtgccagtt ttaaccagat ggtcaccgcg ctggagcgca tgatgacctc tcagcagcgt
     8581 ctgctttctg atatctctca cgagctgcgc accccgctga cgcgtctgca actgggtacg
     8641 gcgttactgc gccgtcgtag cggtgaaagc aaggaactgg agcgtattga aaccgaagcg
     8701 caacgtctgg acagcatgat caacgatctg ttggtgatgt cacgtaatca gcaaaaaaac
     8761 gcgctggtta gcgaaaccat caaagccaac cagttgtgga gtgaagtgct ggataacgcg
     8821 gcgttcgaag ccgagcaaat gggcaagtcg ttgacagtta acttcccgcc tgggccgtgg
     8881 ccgctgtacg gcaatccgaa cgccctggaa agtgcgctgg aaaacattgt tcgtaatgct
     8941 ctgcgttatt cccatacgaa gattgaagtg ggctttgcgg tagataaaga cggtatcacc
     9001 attacggtgg acgacgatgg tcctggcgtt agcccggaag atcgcgaaca gattttccgt
     9061 ccgttctatc gtaccgatga agcacgcgat cgtgaatctg gcggtacagg tttggggctg
     9121 gcgattgttg aaaccgccat tcagcagcat cgtggctggg tgaaggcaga agacagcccg
     9181 ctgggcggtt tacggctggt gatttggttg ccgctgtata agcggagtta aacttcgcat
     9241 ttgcaggcag gataaggcgt ttacgccgca tccggcattt gagcaggatg cctgatgcga
     9301 cgctgatagc gtcttatcag gcctacactc cgggggttat tttccccaca accggcggga
     9361 aaaatcttcg atcttgccgc tcagtcggcg cttttgcatc gtccgcgtcc agcttttcga
     9421 taacccggca gcggagagta aacggtgata ttgatcgtca tcaaacggca tatgccatgc
     9481 gatggcggca gcctcctgca cggtcacatc gctgacacgg gaaaccaact ccagcggcgc
     9541 gtccgcagac actttccctg gcgctatcac gctatacaac caccccacct tacctgtgtt
     9601 ttgcatcaac tgcgctatat cgctgatatc aaaatggtaa ttgagtttat agcaaggcga
     9661 gcgcggctgg ctgacctgaa ttaatgcctc tccccagcgg aaaatatcgc ccatataaac
     9721 attactttcc gtcaggccgt cggttgagag gttttcacca aacgcaggcg caacaaacaa
     9781 ctccgcctgt tccggaaatt cccgcgccca gtagagataa tgctcacgag gataatgaca
     9841 cagcgctctg tctggcccgc cgtgaacctt tttctccgcc tgctcgtcac cttccagccc
     9901 cagctccgtc agcatcaact caccatcaac ctggatttta gcaattgcgc tgggtttgcc
     9961 ttcgggataa gcctgaatct tgcctgtgta tacatcaacc ggatatcgca tctgttccct
    10021 ctccacgaga aatttcccca ttagaccata tttattttat gtcaggcgtg ctgttttcgc
    10081 ggtaagtatc caggcaggaa ctcaatagca aaccggacga acgttagttc atccggctgt
    10141 ggggattaag gaagcaggtt tatttcaccg tacctaaaat gtcgattttc gctgctctgg
    10201 ctttgacttt acgtgaccag atagaggtaa gaattggcac cagaatcgaa gtcacaatga
    10261 ccgccgtcgc taccagcgaa gttgctgccg gagccatcgg tttaaacgca ggcaccattt
    10321 ctgcaatcag cacaggtgtc gctaccgcgg cccctgcgga actggaagcg gcaattccgg
    10381 cagtgccatc gccaccgcca atcaatttat cggcgataat caacggaata ccggtcacga
    10441 taattactgc cacacccaac aggatcccca gcaaaccagt ctgggcaatc acagtcaaat
    10501 caatggtatt gcccagcgcg aaggcaaaga atggaatcag cgtttgcacc gctttgctga
    10561 aaaattctcg caattcaggg tcaaggttcc ccagggcaaa gcccaccagg aacggtaata
    10621 ctgcgccgac gaaaacatgc ggttcaaacg aggcaatccc ggcagtgccc agaataatca
    10681 tcgtcatgag cggcccggac tccaacgaca tcaacacaaa tgccccagct tcttcttttg
    10741 tgccgtactg ctgcatgatg gaagcgtaaa gtccgccatt ggtcatatcc atcgccgcca
    10801 ccagcgccag cgttgaaagt ccggcaaaga atccaacttc aacaccatgt tccggaataa
    10861 tacgcgaggc aattgccgca accacccacg cgacggcaat tttagttacc accagcgtac
    10921 cggatttacg cagtaccgtt cccgtcgcgc ttaattttat tgacgccccc atgcaaaaaa
    10981 accacaccgc cagaatgggc accgtaccgg taatcatccc gttggtgaat gatccaaaat
    11041 atttccccgc ccccggcgag aaggtgtggc acagtgcgcc aaggaatagc gggacgagca
    11101 tcatcccccc cgggattttc tcaatcgagc gttttatctg catttccatc acctgtcggc
    11161 atatttttaa gggctgatgc gtaattcctc aatggagcat cagtgttgat ggaaacgaag
    11221 atagacattc atttaatcaa taaaagtgat caaaaccaca tcaattgaaa cgctgtttta
    11281 tttttatcgg atcattgttt ttattttgaa attgatcaca aaaaaaacca ccgccgttgg
    11341 cgatggttca ttttttaagc tgatatgcgg cctatacgcc tcattgcagc aggcggcaaa
    11401 tgattatttt ttcgccgcaa aacgtgccgc tgcttcgtcc cagttcacca cgttccagaa
    11461 ctctttaatg tagtccggac ggcggttctg gaatttcagg tagtaagcat gttcccacac
    11521 atccaggccc ataatcggga agccggaagc gccagaaata gcttcaccca tcagcggaga
    11581 atcctggtta gcagtagaaa ccaccgccag tttatcgcct ttcagcacca gccatgccca
    11641 gccggaacca aagcgggaag ctgccgcttt ttcaaattct gctttgaagt tatcaacgga
    11701 gccgaagtca cgttcgatag ccgctttcag gtcaccctgc agggtggtgc cttttttcag
    11761 acctttccag aacaggctgt ggttagcgtg accgccagcg ttgttgcgca gtacggtttt
    11821 cttgtctgct ggcagctggt ccagtttggt gatcagctct tcaaccggca ggttggcaaa
    11881 ttctggcagg ctttccagcg ccgcgttggc gttgtttacg taggtctgat ggtgtttggt
    11941 gtggtggatt tccatggtct gcttatcgaa gtgcggttcc agggcatcgt aagcatacgg
    12001 cagggatggc agggtatagc tcatattcat ctccagtatt gtcgggcggc cgattgttaa
    12061 tgccgcgtaa gcagttggtt cattatagtt aattaaatga tattgaaaat gattatcaat
    12121 gccgtacttt tcgtaagggt atggttttgc aggaaaatgc ccgagatgtg aagcaaatca
    12181 cccacttaat gccgtgattg ccagtaaatc gacaacggcg gcaacaggcg aaaggttaat
    12241 cgacagcacg atttttacac tcatctcgtc ggagatgtga cgcgacgaaa aatgatgagg
    12301 ataagaagat gagtaacgcg attacgatgg ggatattttg gcatttgatc ggcgcggcca
    12361 gtgcagcctg tttttacgct ccgttcaaaa aagtaaaaaa atggtcatgg gaaaccatgt
    12421 ggtcagtcgg tgggattgtt tcgtggatta ttctgccgtg ggccatcagc gccctgttac
    12481 taccgaattt ctgggcgtat tacagctcgt ttagtctctc tacgctactg cctgtttttc
    12541 tgttcggcgc tatgtggggg atcggtaata tcaactacgg cctgaccatg cgttatctcg
    12601 gcatgtcgat gggaattggc atcgccattg gcattacgtt gattgtcggt acgctgatga
    12661 cgccaattat caacggcaat ttcgatgtgt tgattagcac cgaaggcgga cgcatgacgt
    12721 tgctcggcgt tctggtggcg ctgattggcg tagggattgt aactcgcgcc gggcagttga
    12781 aagagcgcaa gatgggcatt aaagccgaag agttcaatct gaaaaaaggg ctggtgctgg
    12841 cggtgatgtg cggcattttc tctgccggga tgtcctttgc gatgaacgcc gcaaaaccga
    12901 tgcatgaagc cgctgccgca cttggcgtcg atccactgta tgtcgctctg ccaagctatg
    12961 ttgtcatcat gggcggcggc gcgatcatta acctcggttt ctgttttatt cgtctggcaa
    13021 aagtgaagga tttgtcgcta aaagccgact tctcgctggc aaaatcgctg atcattcaca
    13081 atgtgttact ctcgacactg ggcgggttga tgtggtatct gcaattcttt ttctatgcct
    13141 ggggccacgc ccgcattccg gcgcagtatg actacatcag ttggatgctg catatgagtt
    13201 tctatgtatt gtgcggcggt atcgtcgggc tggtgctgaa agagtggaac aatgcaggac
    13261 gccgtccggt aacggtgttg agcctcggtt gtgtggtgat tattgtcgcc gctaacatcg
    13321 tcggcatcgg catggcgaat taatctttct gcgaattgag atgacgccac tggctgggcg
    13381 tcatcccggt ttcccgggta aacaccaccg aaaaatagtt actatcttca aagccacatt
    13441 cggtcgaaat atcactgatt aacaggcggc tatgctggag aagatattgc gcatgacaca
    13501 ctctgacctg tcgcagatat tgattgatgg tcattccagt ctgctggcga aattgctgac
    13561 gcaaaacgcg ctcactgcac gatgcctcat cacaaaattt atccagcgca aagggacttt
    13621 tcaggctagc cgccagccgg gtaatcagct tatccagcaa cgtttcgctg gatgttggcg
    13681 gcaacgaatc actggtgtaa cgatggcgat tcagcaacat caccaactgc ccgaacagca
    13741 actcagccat ttcgttagca aacggcacat gctgactact ttcatgctca agctgaccga
    13801 taacctgccg cgcctgcgcc atccccatgc tacctaagcg ccagtgtggt tgccctgcgc
    13861 tggcgttaaa tcccggaatc gccccctgcc agtcaagatt cagcttcaga cgctccgggc
    13921 aataaataat attctgcaaa accagatcgt taacggaagc gtaggagtgt ttatcgtcag
    13981 catgaatgta aaagagatcg ccacgggtaa tgcgataagg gcgatcgttg agtacatgca
    14041 ggccattacc gcgccagaca atcaccagct cacaaaaatc atgtgtatgt tcagcaaaga
    14101 catcttgcgg ataacggtca gccacagcga ctgcctgctg gtcgctggca aaaaaatcat
    14161 ctttgagaag ttttaactga tgcgccaccg tggctacctc ggccagagaa cgaagttgat
    14221 tattcgcaat atggcgtaca aatacgttga gaagattcgc gttattgcag aaagccatcc
    14281 cgtccctggc gaatatcacg cggtgaccag ttaaactctc ggcgaaaaag cgtcgaaaag
    14341 tggttactgt cgctgaatcc acagcgatag gcgatgtcag taacgctggc ctcgctgtgg
    14401 cgtagcagat gtcgggcttt catcagtcgc aggcggttca ggtatcgctg aggcgtcagt
    14461 cccgtttgct gcttaagctg ccgatgtagc gtacgcagtg aaagagaaaa ttgatccgcc
    14521 acggcatccc aattcacctc atcggcaaaa tggtcctcca gccaggccag aagcaagttg
    14581 agacgtgatg cgctgttttc caggttctcc tgcaaactgc ttttacgcag caagagcagt
    14641 aattgcataa acaagatctc gcgactggcg gtcgagggta aatcattttc cccttcctgc
    14701 tgttccatct gtgcaaccag ctgtcgcacc tgctgcaata cgctgtggtt aacgcgccag
    14761 tgagacggat actgcccatc cagctcttgt ggcagcaact gattcagccc ggcgagaaac
    14821 tgaaatcgat ccggcgagcg atacagcaca ttggtcagac acagattatc ggtatgttca
    14881 tacagatgcc gatcatgatc gcgtacgaaa cagaccgtgc caccggtgat ggtatagggc
    14941 tgcccattaa acacatgaat acccgtgcca tgttcgacaa tcacaatttc atgaaaatca
    15001 tgatgatgtt caggaaaatc cgcctgcggg agccggggtt ctatcgccac ggacgcgtta
    15061 ccagacggaa aaaaatccac actatgtaat acggtcatac tggcctcctg atgtcgtcaa
    15121 cacggcgaaa tagtaatcac gaggtcaggt tcttacctta aattttcgac ggaaaaccac
    15181 gtaaaaaacg tcgatttttc aagatacagc gtgaattttc aggaaatgcg gtgagcatca
    15241 catcaccaca attcagcaaa ttgtgaacat catcacgttc atctttccct ggttgccaat
    15301 ggcccatttt cctgtcagta acgagaaggt cgcgaattca ggcgcttttt agactggtcg
    15361 taatgaaatt cagcaggatc acattatgac ctttcgcaat tgtatcgccg tcgatctcgg
    15421 cgcatccagt gggcgcgtga tgctggcgcg ttacgagcgt gaatgccgca gcctgacgct
    15481 gcgcgaaatc catcgtttta acaatgggct gcatagtcag aacggctatg tcacctggga
    15541 tgtggatagc cttgaaagtg ccattcgcct tggattaaac aaggtgtgcg aggaagggat
    15601 tcgtatcgat agcattggga ttgatacctg gggcgtggac tttgtgctgc tcgaccaaca
    15661 gggtcagcgt gtgggcctgc ccgttgctta tcgcgatagc cgcaccaatg gcctaatggc
    15721 gcaggcacaa caacaactcg gcaaacgcga tatttatcaa cgtagcggca tccagtttct
    15781 gcccttcaat acgctttatc agttgcgtgc gctgacggag caacaacctg aacttattcc
    15841 acacattgct cacgctctgc tgatgccgga ttacttcagt tatcgcctga ccggcaagat
    15901 gaactgggaa tataccaacg ccacgaccac gcaactggtc aatatcaata gcgacgactg
    15961 ggacgagtcg ctactggcgt ggagcggggc caacaaagcc tggtttggtc gcccgacgca
    16021 tccgggtaat gtcataggtc actggatttg cccgcagggt aatgagattc cagtggtcgc
    16081 cgttgccagc catgataccg ccagcgcggt tatcgcctcg ccgttaaacg gctcacgtgc
    16141 tgcttatctc tcttctggca cctggtcatt gatgggcttc gaaagccaga cgccatttac
    16201 caatgacacg gcactggcag ccaacatcac caatgaaggc ggggcggaag gtcgctatcg
    16261 ggtgctgaaa aatattatgg gcttatggct gcttcagcga gtgcttcagg agcagcaaat
    16321 caacgatctt ccggcgctta tctccgcgac acaggcactt ccggcttgcc gcttcattat
    16381 caatcccaat gacgatcgct ttattaatcc tgagacgatg tgcagcgaaa ttcaggctgc
    16441 gtgtcgggaa acggcgcaac cgatcccgga aagtgatgct gaactggcgc gctgcatttt
    16501 cgacagtctg gcgctgctgt atgccgatgt gttgcatgag ctggcgcagc tgcgcggtga
    16561 agatttctcg caactgcata ttgtcggcgg aggctgccag aacacgctgc tcaaccagct
    16621 atgcgccgat gcctgcggta ttcgggtgat cgccgggcct gttgaagcct cgacgctcgg
    16681 caatatcggc atccagttaa tgacgctgga tgaactcaac aatgtggatg atttccgtca
    16741 ggtcgtcagc accaccgcga atctgaccac ctttacccct aatcctgaca gtgaaattgc
    16801 ccactatgtg gcgcagattc actctacacg acagacaaag gagctttgcg catgaccact
    16861 caactggaac aggcctggga gctagcgaaa cagcgtttcg cggcggtggg gattgatgtc
    16921 gaggaggcgc tgcgccaact tgatcgttta cccgtttcaa tgcactgctg gcagggcgat
    16981 gatgtttccg gttttgaaaa cccggaaggt tcgctgaccg gggggattca ggccacaggc
    17041 aattatccgg gcaaagcgcg taatgccagt gagctacgtg ccgatctgga acaggctatg
    17101 cggctgattc cggggccgaa acggcttaat ttacatgcca tctatctgga atcagatacg
    17161 ccagtctcgc gcgaccagat caaaccagag cacttcaaaa actgggttga atgggcgaaa
    17221 gccaatcagc tcggtctgga ttttaacccc tcctgctttt cgcatccgct aagcgccgat
    17281 ggctttacgc tttcccatgc cgacgacagc attcgccagt tctggattga tcactgcaaa
    17341 gccagccgtc gcgtttcggc ctattttggc gagcaactcg gcacaccatc ggtgatgaac
    17401 atctggatcc cggatggtat gaaagatatc accgttgacc gtctcgcccc gcgtcagcgt
    17461 ctgctggcag cactggatga ggtgatcagc gagaagctaa accctgcgca ccatatcgac
    17521 gccgttgaga gcaaattgtt tggcattggc gcagagagct acacggttgg ctccaatgag
    17581 ttttacatgg ggtatgccac cagccgccag actgcgctgt gcctggacgc cgggcacttc
    17641 cacccgactg aagtgatttc cgacaagatt tccgccgcca tgctgtatgt gccgcagttg
    17701 ctgctgcacg tcagccgtcc ggttcgctgg gacagcgatc acgtagtgct gctggatgat
    17761 gaaacccagg caattgccag tgagattgtg cgtcacgatc tgtttgaccg ggtgcatatc
    17821 ggccttgact tcttcgatgc ctctatcaac cgcattgccg cgtgggtcat tggtacacgc
    17881 aatatgaaaa aagccctgct gcgtgcgttg ctggaaccta ccgctgagct gcgcaagctg
    17941 gaagaggcgg gcgattacac tgcgcgtctg gcactgctgg aagagcagaa atcgttgccg
    18001 tggcaggcgg tctgggaaat gtattgccaa cgtcacgata cgccagcagg tagcgaatgg
    18061 ctggagagcg tgcgggctta tgagaaagaa attttgagtc gccgcgggta aacactgccg
    18121 gatgcggcgc gagcgcctta tccggcctac gggtcggcaa cagttgtagg cctgataaga
    18181 cgcgacagcg tcgcatcagg cattgattgc cggatgcggc acaagtgcct tatccggcct
    18241 acaggtcggc aatagttgta ggcctgataa gacgcgacag cgtcgcatca ggcattgatt
    18301 gccggatgcg gcacaagtgc cttatccggc ctacaggtcg gcaacagttg taggcctgat
    18361 aagacgcgac agcgtcgcat caggcattga ttgccggatg cggcacaagt gccttatcag
    18421 gcctacaggt cggcaatagt tgtaggcctg ataagacgcg acagcgtcgc atcaggcatt
    18481 gattgccgga tgcggcgcga gcgccttatc cggcctacgg gtcgtgcatc cgacaacacc
    18541 gaatttacag gaacacagaa catgcaaaac attactcagt cctggtttgt ccagggaatg
    18601 atcaaagcca ccaccgacgc ctggctgaaa ggctgggatg agcgcaacgg cggcaacctg
    18661 acgctacgcc tggatgacgc cgatatcgca ccatatcacg acaatttcca ccaacaaccg
    18721 cgctatatcc cgctcagcca gcccatgcct ttactggcaa atacaccgtt tattgtcacc
    18781 ggctcgggca aattcttccg taacgtccag cttgatcctg cggctaactt aggcatcgta
    18841 aaagtcgaca gcgacggcgc gggctaccac attctttggg ggttaaccaa cgaagccgtc
    18901 cccacttccg aacttccggc tcacttcctt tcccactgcg agcgcattaa agccaccaac
    18961 ggcaaagatc gggtgatcat gcactgccac gccaccaacc tgatcgccct cacctatgta
    19021 cttgaaaacg acaccgcggt cttcactcgc caactgtggg aaggcagcac cgagtgtctg
    19081 gtggtattcc cggatggcgt tggcattttg ccgtggatgg tgcccggcac ggacgaaatc
    19141 ggccaggcga ccgcacaaga gatgcaaaaa cattcgctgg cgttgtggcc cttccacggc
    19201 gtcttcggca gcggaccgac gctggatgaa accttcggtt taatcgacac cgcagaaaaa
    19261 tcagcacaag tattagtgaa ggtttattcg atgggcggca tgaaacagac catcagccgt
    19321 gaagagttga tagcgctcgg caagcgtttc ggcgttacgc cactcgccag tgcgctggcg
    19381 ctgtaaggag caaacatgat ccgcaaagcc tttgtcatgc aggtaaaccc cgacgcccac
    19441 gaagagtatc agcgtcggca taatcccatc tggccagaac tggaagcagt gctgaaatct
    19501 cacggtgcgc ataactacgc catctatctc gacaaagcgc gtaatctgct gtttgccatg
    19561 gtagagattg aatctgaaga acgctggaat gcggttgcca gcactgatgt ttgccaacgt
    19621 tggtggaaat atatgaccga tgttatgccc gctaacccgg ataacagccc ggtgagtagc
    19681 gagctgcaag aagtgtttta cctgccgtaa ttgcccaatg tgccagagat gcctccggca
    19741 caatatttta aatttcgatt tgaaaaatta aacatattac atctcccggt aagttatatt
    19801 tccctgatac attgtgagta aatcacaaaa ataatgaata acccattaat gattcat
//
LOCUS       DAPHKZ010000082        19776 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.082, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000082 DAPHKZ010000000
VERSION     DAPHKZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19776
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.082"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            133..807
                     /locus_tag="RH288_003054"
     CDS             133..807
                     /locus_tag="RH288_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001413617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032090.1"
                     /translation="MIFSALKEIYDGDPGFIFDKISHKLRHTVTEFDESGKSEPTDLF
                     TWYGKDKKGDSLAIVVKNKNGNDYLSLGYYDQDDYHIQRGIRINGDSLTQYCSENARS
                     ASAWFESSKAIMAESFATGSDHQVVNELNGERLREPNDVFKRYGRAIRYDFQVDDAKY
                     KCDHLKEIVSTLVGNKINVGHSQKIYKHFKDLEGKIEERLQNRQAEYQNKINQPSAPG
                     VNFDDI"
     gene            complement(989..1744)
                     /gene="mlaA"
                     /locus_tag="RH288_003055"
     CDS             complement(989..1744)
                     /gene="mlaA"
                     /locus_tag="RH288_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HDV4032091.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNF
                     NVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTR
                     FFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRD
                     DGGDMADGLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGELKPQENPNAQAIQDDLKDIDSE"
     gene            2038..2970
                     /locus_tag="RH288_003056"
     CDS             2038..2970
                     /locus_tag="RH288_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDV4032092.1"
                     /translation="MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHI
                     RQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFQVELEGVPGSFLLENLGYTFGF
                     IIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLIRLWGVVLLGNILGTGIAAWAFEY
                     MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIIL
                     MTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMS
                     HAQIRNDMSNKRKAEARQKAERAENIKKNYKNPA"
     gene            3046..3120
                     /locus_tag="RH288_003057"
     tRNA            3046..3120
                     /locus_tag="RH288_003057"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3079..3081,aa:Arg,seq:cct)
     gene            complement(3216..4151)
                     /gene="dsdC"
                     /locus_tag="RH288_003058"
     CDS             complement(3216..4151)
                     /gene="dsdC"
                     /locus_tag="RH288_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DsdC"
                     /protein_id="HDV4032093.1"
                     /translation="MEPLREIRNRLLNGWQLSKMHTFEVAARHQSFALAAEELSLSPS
                     AVSHRINQLEEELGIQLFVRSHRKVELTHEGKRVYWALKSSLDTLNQEILDIKNQELS
                     GTLTLYSRPSIAQCWLVPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDDAP
                     SAQLTHHFLMDEEILPVCSPEYAQRHALTNTVINLCHCTLLHDRQAWSNDSGTDEWHS
                     WAQHYAVNLPTSSGIGFDRSDLAVIAAMNHIGVAMGRKRLVQKRLASGELVAPFGDMT
                     VKCHQHYYITTLPGRQWPKIEAFITWLREQVKTTS"
     gene            4369..5706
                     /gene="dsdX"
                     /locus_tag="RH288_003059"
     CDS             4369..5706
                     /gene="dsdX"
                     /locus_tag="RH288_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
                     /protein_id="HDV4032094.1"
                     /translation="MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMM
                     GMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSVD
                     VIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
                     HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLK
                     VRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGLYILVEFIGNPITAMFIAV
                     FVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILKSSSLADTLAVI
                     LSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGS
                     GAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII"
     gene            5724..7052
                     /gene="dsdA"
                     /locus_tag="RH288_003060"
     CDS             5724..7052
                     /gene="dsdA"
                     /locus_tag="RH288_003060"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HDV4032095.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     TAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA
                     GPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR"
     gene            complement(7160..8698)
                     /gene="emrY"
                     /locus_tag="RH288_003061"
     CDS             complement(7160..8698)
                     /gene="emrY"
                     /locus_tag="RH288_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HDV4032096.1"
                     /translation="MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTI
                     SGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSL
                     STNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
                     LGGYICDNFSWGWIFLINVPMGIVVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVG
                     GLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWESTSENPILDLSLFKSRNFTI
                     GIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNK
                     IDMRVLVTFSFLMYAVCYYWRSVTFMPTIDFTGIIMPQFFQGFAVACFFLPLTTISFS
                     GLPDNKFANASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSS
                     SQIMDKYYGSLSGVLNEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTA
                     KGVG"
     gene            complement(8698..9861)
                     /gene="emrK"
                     /locus_tag="RH288_003062"
     CDS             complement(8698..9861)
                     /gene="emrK"
                     /locus_tag="RH288_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrK"
                     /protein_id="HDV4032097.1"
                     /translation="MEQINSNKKHSNRRKYFSLLAVVLFIAFSGAYAYWSMELEDMIS
                     TDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDILVSLDKTDATIALNKAKNNLA
                     NIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKETLEHTKDTL
                     ISSKAALNAAIQAYKANKALVMNTPLNRQPQVVEAADATKEAWLALKRTDIKSPVTGY
                     IAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQLTDVRIGQSVNIISDLYGENV
                     VFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEHPLRIGLSM
                     TATIDTKNEDIAEMPELASTVTSMPAYTSKALVIDTSPIEKEISNIISHNGQL"
     gene            10277..10891
                     /gene="evgA"
                     /locus_tag="RH288_003063"
     CDS             10277..10891
                     /gene="evgA"
                     /locus_tag="RH288_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system DNA-binding response
                     regulator EvgA"
                     /protein_id="HDV4032098.1"
                     /translation="MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETL
                     KPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSK
                     KEGMNNIIAAIGAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
                     NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG"
     gene            10896..14489
                     /gene="evgS"
                     /locus_tag="RH288_003064"
     CDS             10896..14489
                     /gene="evgS"
                     /locus_tag="RH288_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HDV4032099.1"
                     /translation="MKFLPYIFLLCCALWSTMSFADEDYIEYRGISSNNRVTLDPLRL
                     SNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRVRGINADYLNLLKRALNIKLTLRE
                     YADHQKAMDALEEGEVDIVLSHLVASPPLNDDIAATKPLIITFPALVTTLHDSMRPLT
                     SPKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGHNDYFIGSNIITSS
                     MISRYFTHSLNVVKYYNSPRQYNFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWL
                     DTGNLAFLNKPLELTEHEKQWIKQHPNLKVLENPYSPPYSMTDENGSVRGVMGDILNI
                     ITLQTGLNFSPITVSHNIHAGTQLSPGGWDIIPGAIYSEDRENNVLFAEAFITTPYVF
                     VMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIQVDNASAAFHKVKEGELD
                     ALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPRGEPELKDIINKALNAIPP
                     SEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKV
                     IQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENS
                     DSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASDNAVYI
                     CGWQDITETRDLINALEVEKNKAIKATVAKSQFLATMSHEIRTPISSIMGFLELLSGS
                     GLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHS
                     FGAIAASKSIALSCSSTFPEHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLG
                     HIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNM
                     QGDLSLESHPGIGTTFTITIPVEISQQVATVEAKAEQPITLPEKLSILIADDHPTNRL
                     LLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFELTRKLREQNSS
                     LPIWGLTANAQANEREKGLSCGMNLCLFKPLTLDVLKTHLSQLHQVAHIAPQYRHLDI
                     EALKNNTANDLQLMQEILMTFQHETHKDLPAAFQALEAGDNRTFHQCIHRIHGAANIL
                     NLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQKND"
     gene            complement(14545..15690)
                     /gene="yfdE"
                     /locus_tag="RH288_003065"
     CDS             complement(14545..15690)
                     /gene="yfdE"
                     /locus_tag="RH288_003065"
                     /EC_number="2.8.3.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416872.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA:oxalate CoA-transferase"
                     /protein_id="HDV4032100.1"
                     /translation="MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPP
                     GHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFR
                     PGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
                     DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMA
                     YIATGKSPQRLGNRHPYMAPFDVFNTQDKPITICCGNDKLFSALCQALELTELVNDPR
                     FSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPLLSVAEAIKLPQTQA
                     RNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS"
     gene            complement(15764..16708)
                     /gene="yfdV"
                     /locus_tag="RH288_003066"
     CDS             complement(15764..16708)
                     /gene="yfdV"
                     /locus_tag="RH288_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter YfdV"
                     /protein_id="HDV4032101.1"
                     /translation="MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYA
                     LPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCAL
                     IAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
                     NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLT
                     LAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGII
                     IASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS"
     gene            complement(16778..18472)
                     /gene="oxc"
                     /locus_tag="RH288_003067"
     CDS             complement(16778..18472)
                     /gene="oxc"
                     /locus_tag="RH288_003067"
                     /EC_number="4.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="HDV4032102.1"
                     /translation="MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAE
                     GIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMI
                     SGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
                     GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIIL
                     GKGAAYSQADEQLREFIESAQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVML
                     VGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELK
                     QNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLV
                     NEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
                     GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDA
                     FRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN"
     gene            complement(18526..19776)
                     /gene="frc"
                     /locus_tag="RH288_003068"
     CDS             complement(18526..19776)
                     /gene="frc"
                     /locus_tag="RH288_003068"
                     /EC_number="2.8.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyl-CoA transferase"
                     /protein_id="HDV4032103.1"
                     /translation="MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDV
                     TRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAI
                     DHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPP
                     LVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRL
                     DKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQN
                     WENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIP
                     CAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEH
                     TAAVLQELGYSDDEIAAMKQNHAI"
BASE COUNT         5650 a         4496 c         4292 g         5338 t
ORIGIN      
        1 gaccatatta ctattggtat cgacaaccaa gaaccaatag aattacctgc gaactataaa
       61 gacaaagaac tcgtccgtac tatcattaat gacaacatag ttgagaagac tcatgatatc
      121 aataacaagg aaatgatctt cagcgcatta aaagaaatat atgatggaga tcctggtttt
      181 atcttcgata agatatcaca caaactcaga catacggtaa cggaatttga tgagagcggg
      241 aaaagcgaac caacggactt atttacctgg tacggtaaag ataaaaaagg cgactctctc
      301 gctattgtag ttaaaaataa aaacggaaat gattacttat ctctcggtta ctacgatcag
      361 gacgactacc acattcaaag aggaattcgt attaatggtg atagtctcac ccaatattgt
      421 agtgaaaacg ccaggagtgc ttcagcgtgg tttgaaagca gtaaagctat catggcagaa
      481 tcatttgcaa ctggttccga tcatcaggtt gtaaacgagc tcaacgggga aagactgaga
      541 gaaccaaacg acgtttttaa acgttatggt cgagcaataa gatatgattt tcaagtggac
      601 gatgcaaaat ataaatgcga ccatctaaaa gaaatagttt ctactttagt cggtaacaaa
      661 attaacgttg gccattctca aaaaatatat aagcatttta aggatctcga aggtaaaatt
      721 gaagaaaggc ttcaaaatcg ccaggctgaa tatcaaaata aaattaatca accatctgcg
      781 ccaggtgtta attttgatga tatttaaaat tatttttcca gttttttgat ttttcaacag
      841 ctgaatatcg gaaatagtca gtgacgaaca tcagtatttt tacataatta cgtctaggtc
      901 attgtcggtt tatctccttt tacttgtggt aattgaggga taacaacaaa aaaggtgagt
      961 tttgcgactc acctttttta tttgtttctt attcagaatc aatatctttt aaatcatcct
     1021 gaatcgcttg tgcgttcgga ttttcctgcg gtttgagttc gccgccatta gcgatgaaat
     1081 catgacgctg gaagtacgct tcgcgcacca taatataagg atcggacgac tgacgcagca
     1141 gaccatcgga atccagcagc tgagcgcggg tttcgatccc ttcaagcgtc catttaccca
     1201 cagacatcgg ccaggtcagc caggaaagaa ccgggtaaag accatccgcc atatcaccac
     1261 cgtcatcacg cagcgtgaag ctaccgtaga acggtaactg aacgtaaggc ccataaccca
     1321 cgccataatg accaagcgta ctaccgaagc ggtgaggttc agtccgttgc agtttcgggt
     1381 tcgccatccc tgcaacatca ataaagccgc ccatccccaa aatggtgttc aggaaaaagc
     1441 gggtaaagtg gaccatcccc tgataagggt cgccctgcaa gaagtagtta accatcaccg
     1501 caggttcttc aaggttgcca gtaaagttgc tcaaaccatt acgcgccggt tgcggaacat
     1561 aatcacgcca ggcgacagcg accggtcgaa caatatacgg gtctaatacg ttgaagttga
     1621 agttgtacat ggtgcggttg aacccttcta acgggtcaga acgcccttgc tgatctgtac
     1681 cggaactcgc acaccccacc agaagcgtag ttcccagagc aagcgccgac aggcgaagct
     1741 tcataaatgt ctccctgttt ttttatggct tatgcagttt gccatccatg acggaacgat
     1801 accgtatccg cctgtttagg tgtgggcgat tgtaacagca cgtcaactga tgtccagacg
     1861 ccctgatttg ctgatttgat catagcctgg taatcgccgc cctgtaggct acttgattct
     1921 atagaaacag aaaaaggcaa acgcagcctt ttctacattt tcagagtaac tcccgtcagt
     1981 tgcgagcaaa aaagccgcta cgctttagct atacgtgcta attcaagaga agagaccatg
     2041 gacaacgaca aaattgatca acacagcgac gaaattgaag ttgagagcga agaaaaagag
     2101 cgcggcaaaa aaatagaaat agatgaagac cgactcccct cccgggcgat ggcaattcat
     2161 gagcatatcc gccaggatgg tgaaaaagag ctggaacgcg acgcaatggc gctactgtgg
     2221 tcagccattg cggcgggtct gtcgatgggc gcttcgttac tggcaaaagg gatatttcaa
     2281 gtcgaactgg aaggtgtgcc gggcagcttc ttgctggaga atctcggtta tacctttggt
     2341 tttattatcg tcattatggc ccgccagcaa ttatttaccg aaaataccgt gactgcggta
     2401 ctacccgtca tgcaaaaacc gacaatgagc aacgtcggct tacttatacg gttatggggc
     2461 gtcgtgctgc tgggtaatat tctcgggaca ggtattgcgg cgtgggcatt tgaatatatg
     2521 cctatcttca atgaagaaac tcgcgatgca tttgtcaaaa tcggcatgga tgtgatgaag
     2581 aacaccccca gcgagatgtt tgccaacgcg atcatttccg gctggctgat cgccactatg
     2641 gtttggatgt ttcctgcagc gggtgcggca aagattgtgg tgattatatt gatgacctgg
     2701 cttattgccc tgggtgacac cacccatatc gtggtcggtt ctgttgaaat cctctatctg
     2761 gtgtttaacg gtacgctgca ctggagcgat ttcatctggc ccttcgcact acctacttta
     2821 gcggggaaca tctgcggcgg cacctttatc ttcgcgttaa tgagtcatgc acagattcgt
     2881 aacgacatga gcaataagcg taaagcagaa gcacgccaaa aagcagaacg tgcggaaaac
     2941 attaagaaaa attataaaaa cccggcataa atggcgaggg tttaagcaat cgagcggcag
     3001 cgtacttacc ccgcactcca ttagcgggta tactcatgcc gcattgtcct cttagttaaa
     3061 tggatataac gagcccctcc taagggctaa ttgcaggttc gattcctgca ggggacacca
     3121 tccttgtgtt tatccctaaa accacataaa aaccgtaaat taaattcgaa ctagcaggcc
     3181 gaataaggca caccaggaac tcgtggtttt attcattatg aagtggtttt tacctgttct
     3241 cttagccagg taataaacgc ttcaattttt ggccactgcc tgcccggtaa tgtggtgatg
     3301 taataatgct gatggcattt caccgtcata tcgccaaacg gcgcgacgag ctcaccactg
     3361 gcaagccttt tttgtaccag gcgttttctt cccatcgcca ccccaatatg attcatcgcg
     3421 gcaataacag ctaaatcaga acgatcaaag ccaattccag aagatgtcgg caaattaacc
     3481 gcataatgtt gcgcccaact atgccattca tccgtaccgg agtcgttgct ccatgcctgt
     3541 ctgtcatgga gcaacgtaca gtgacacagg ttaattaccg tgttggttaa agcatgtctt
     3601 tgagcgtatt ccgggctaca tactggcagg atttcttcat ccatcagaaa gtgatgagtg
     3661 agttgcgctg acggcgcatc atcaaagtag atcgccaaat cgattccggc acgttgcaga
     3721 ttgacgttgt cattaccagt gagcacggtg agcgaaatag acggataccg gcgtgtaaag
     3781 tcacctaatg cgggcaccaa ccagcattgg gcgatagagg gccgggaata cagagttaac
     3841 gttcccgata actcctgatt tttgatatca agaatttcct ggttcagggt atccagcgac
     3901 gattttagcg cccaataaac acgtttcccc tcgtgcgtta attccacttt gcgatgggaa
     3961 cgaacaaaca actgaatgcc caattcttct tccagctgat tgatacggtg acttaccgca
     4021 ctggggctca gcgacaattc ctctgccgcc agggcgaagg actgatgcct ggcagccact
     4081 tcaaaagtat gcatttttga taattgccag ccgttaagca gccgatttct tatttcacga
     4141 aggggttcca taatcacctc atttttcgct taagtgtaaa aaaatagcgg caaaatttca
     4201 gctatgagat gagctaaagt gaaccatatc tcaattcacc ttcattttta gatgtaaatc
     4261 actccattga tgcaatttac ctcatgtgaa aggcaaattt tatcgtttgt cagcctgcgt
     4321 tgtttttttg tccaatatca tcaggttaat cacaggggaa ggtgagatat gcactctcaa
     4381 atctgggttg tgagcacgct gcttatcagc atcgtgttaa ttgtactgac catcgtgaag
     4441 ttcaaattcc acccgtttct ggcgctgttg ctggccagct tcttcgtggg aacgatgatg
     4501 ggcatggggc cactggatat ggtaaatgct attgaaagtg gaattggcgg aacgctgggg
     4561 ttcctcgcag cggttatcgg ccttggcacg atactgggaa aaatgatgga agtatccggg
     4621 gccgcagaaa gaattggtct gacacttcaa cgctgccgct ggctttcagt tgatgtcatt
     4681 atggtgctgg ttggcctgat ttgtggcatc acgctgtttg ttgaagtggg cgtcgtgcta
     4741 ttgattcctc tggctttttc aattgccaaa aaaaccaata cctcattatt aaagcttgcc
     4801 attccgctat gtaccgcatt gatggcagtg cactgcgtgg ttcctccaca tccggctgct
     4861 ttatatgttg ccaataagct gggcgcagat atcggttcgg tgatcgtcta cggtttgctg
     4921 gttgggctga tggcatcact gatcggtggc ccacttttcc ttaaatttct gggtcaacga
     4981 ctgcccttta aacctgtacc cacagagttt gcagatctca aagttcgcga tgaaaaaaca
     5041 ctaccgtcat taggcgcaac gttattcacc atactgctac ccattgcgct gatgttggtt
     5101 aaaacgattg ccgaattgaa tatggcgcgt gagagtggtt tgtatatctt ggttgagttt
     5161 attggcaacc ctatcactgc catgtttatc gccgtgtttg tcgcctatta tgtgttgggt
     5221 atacgccagc atatgagcat ggggacgatg ctcacacata cggaaaatgg cttcggttct
     5281 attgctaata ttttgctgat tatcggggcc ggaggcgcat tcaacgccat tttaaaaagc
     5341 agcagtctcg ctgatacgct ggcagttatt ctctccaata tgcatatgca cccgattctt
     5401 ctggcctggt tagtggctct tattctgcat gcggcagtgg gctccgctac cgtggcaatg
     5461 atgggggcaa cggcaattgt tgcacccatg ctgccgcttt atcccgacat cagcccggaa
     5521 attattgcga ttgctatcgg ttcaggtgca attggctgca cgatcgttac ggactcgctt
     5581 ttctggctag tgaagcaata ttgcggcgct acgctcaatg aaacatttaa atactatacg
     5641 acagcgacat ttatcgcttc agtcgtcgct ctggcgggca cattcctgct gtcatttatc
     5701 atctaagcgc aaagagacgt actatggaaa acgctaaaat gaactcgctc atcgcccagt
     5761 atccgttggt aaaggatctg gttgctctta aagaaaccac ctggtttaat cctggcacga
     5821 cctcattggc tgaaggttta ccttatgttg gcctgaccga acaggatgtt caggacgccc
     5881 atgcgcgctt atcccgtttt gcaccctatc tggcaaaagc atttcctgaa actgctgcca
     5941 ctggggggat tattgaatca gaactggttg ccattccagc tatgcaaaaa cggctggaaa
     6001 aagaatatca gcaaccgatc agcgggcaac tgttactgaa aaaagatagc catttgccca
     6061 tttccggctc cataaaagca cgcggcggga tttatgaagt cctggcacac gcagaaaaac
     6121 tggctctgga agcggggttg ctgacgcttg atgatgacta cagcaaactg ctttctccgg
     6181 agtttaaaca gttctttagc caatacagca ttgctgtggg ctcaaccgga aatctggggt
     6241 tatcaatcgg cattatgagc gcccgcattg gctttaaggt gacagttcat atgtctgctg
     6301 atgcccgggc atggaaaaaa gcgaaactgc gcagccatgg cgttacggtc gtggaatatg
     6361 agcaagatta tggtgttgcc gtcgaggaag gacgtaaagc agcgcagtct gacccgaact
     6421 gtttctttat tgatgacgaa aattcccgca cgttgttcct tgggtattcc gtcgctggcc
     6481 agcgtcttaa agcgcaattt gcccagcaag gccgtatcgt cgatgctgat aaccctctgt
     6541 ttgtctatct gccgtgtggt gttggcggtg gtcctggtgg cgtcgcattc gggcttaaac
     6601 tggcgtttgg cgatcatgtt cactgctttt ttgccgaacc aacgcactcc ccttgtatgt
     6661 tgttaggcgt ccatacagga ttacacgatc agatttctgt tcaggatatt ggtatcgaca
     6721 accttaccgc agcggatggc cttgcagttg gtcgcgcatc aggctttgtc gggcgggcaa
     6781 tggagcgtct gctggatggc ttctataccc ttagcgatca aaccatgtat gacatgcttg
     6841 gctggctggc tcaggaagaa ggtattcgtc ttgaaccttc agcactggcg ggtatggccg
     6901 gacctcagcg cgtgtgtgca tcagtaagtt accaacagat gcacggtttc agcgcagaac
     6961 aattgcgtaa tgccactcat ctggtgtggg cgacgggagg tggaatggtg ccggaagaag
     7021 agatgaatca atatctggca aaaggccgtt aataacgttt caacgcagca tcgcaatcct
     7081 ttccctgggt gagcgatgct gccgatggcg cagacttaag atccccggtc ttacccgcta
     7141 taaccccctc cttttatcat cacccaacgc ctttcgctgt aaacggcggt ttcgcaaacc
     7201 aaaccaaaac cgtaagtaag ataaaagcaa tagccgccat acggaaaatc tcatttgcag
     7261 aaatagaaag tgactgctgg gttatttcat tattaatttc attaagaact cctgaaagcg
     7321 aaccatagta tttatccata atttgtgacg atgaattaaa cacggggtta aattgatcga
     7381 tggttgctgt caactgacta tggtgtaacg attcgcgtcg tccccacagc gtcattgtca
     7441 acgacgtacc aactgatcct gacaaggtac gaaaaaaatt actcatactc gaggcattgg
     7501 caaatttatt atctggcaag cctgaaaacg aaatcgttgt taagggtaaa aagaaacagg
     7561 caacggcgaa tccctgaaaa aactgcggca taatgatacc tgtaaaatca atcgttggca
     7621 taaatgtcac agaacgccag taatagcaaa ccgcatacat caaaaaactg aatgtcacca
     7681 acacccgcat gtctattttg ttgccataac gtcctatcaa aggtgaaatt aatagtggca
     7741 tgatgccgat gggcgcataa gcaagtccgg cccatatcgc attatacccc atcgtttcct
     7801 ggagtaactg cggcataagg acgatcgctc cagagtaaaa taaatacgcg catgtgatac
     7861 tcacaatacc aatggtgaag ttacgggact taaacaaact gagatcaaga atcgggttct
     7921 ctgaggtcga ctcccaaatg actaaagaga tcagagaaat aactgatact actgttaata
     7981 ttattatcgt actcgagttg aaccaatcca gatcgcgccc tttatcaagc ataatttgca
     8041 agccaccaac accgagcact aacagggtca gtcctggtag attcattttg accggtgaag
     8101 tctcagtttc tcttccttta agtaaggtta agcataatgt caggacgaca atccccatag
     8161 ggacattgat taaaaatatc caaccccagc taaagttatc acaaatatag ccgcccaata
     8221 tcggcccaca tatcggagcg ataatcacgg tcattgacca taatgccaga gcaaatgtcc
     8281 ttttttctgg tgggtaattc cttaataata aactctgtga cagtggaatt aacggccccg
     8341 ccattaaccc ctgaacgact ctaaaaaata tcagcacatc aagattggtc gataggctac
     8401 acattaatga agacagcgaa aaaaaggtta ctgaaagtaa aaataatctt aattcgccta
     8461 ttctttgtgc caacctgcca gtaacaggga tcgcaatggc atttgctaca ccaaacgagg
     8521 tgataaccca ggtgccttcg tctgttgatg ctcccagaaa gccagatatt gtcggtattg
     8581 cgacgttaga aatagtggaa tccaacattt gcataaatgt cgctaatgac aatgcaatag
     8641 tgacgcacca taacgtccca ccggttaatg gtgccggagt tgatttagtg attgccatta
     8701 aagttgtcca ttatgcgaaa taatgttgct aatttctttt tctatcggac tggtatcgat
     8761 aactaaagcc ttactggtat aagccggcat ggaggtcacg gttgaagcca gctcaggcat
     8821 ctcggcaatg tcttcgttct tcgtatcaat agttgctgtc atcgataaac caatacgcaa
     8881 gggatgttcc atgagttctt ttggatcaag agaaacttca accggtacac gctgaacgat
     8941 tttgatccag ttccctgtcg cattttgtgc aggtaataag gagaacgcat tgccggttcc
     9001 catattgatc cctgtcaccc gaccatgaaa cacaacattt tcaccataaa gatcgctgat
     9061 aatattgacc gattgaccaa tccgtacatc cgtgagttgt gtttctttaa agttggcatt
     9121 aacccacatt tgacgtgccg gtacgacagc cattaacgat tgtccggggc tcactgtttc
     9181 gccgacctga acacttctct gggcaatata gccggtaacc ggactcttaa tatccgtacg
     9241 tttaagcgcc aaccaggctt ctttagttgc atccgccgct tcaacgactt gtggctgacg
     9301 gtttaatggt gtgttcatta ctaaagcttt attcgcttta taagcctgga tagcggcatt
     9361 caatgccgct ttgctactta ttaacgtatc tttggtatgc tccagcgttt cttttgaaat
     9421 aaccccctgc ttcgctaacg gcactcgacg gttataatct tctaaagatt gttgatactg
     9481 aatacgtgct gaagcgactt cggcactgta ttgtttatcc tgtaagtata gtttattcgt
     9541 ttgccgaaca atatttgcca gattattttt agctttattg agtgcgatag tggcatcagt
     9601 tttatccagt gaaactaaaa tgtcaccttg tcgaacgtag ttcgtatctt tatgattaac
     9661 gacagtgaca ctacctgaga cttgtgcaga aattggatct gcattccccg tgacataggc
     9721 gtcatctgta ctaatcatgt cttctaattc cattgaccaa taggcatagg cacctgaaaa
     9781 cgcaataaat aaaactaccg ccaataaaga aaagtatttt cttctgttag aatgtttttt
     9841 atttgaatta atctgttcca ctattatctc tcatttctca tagatgaaat ttatgaattg
     9901 aatgaaaaga gcattcattc ttcatatcaa acacagtgca tgtgttgcac attatcccag
     9961 gaacgttgga ggcctaattt aaatgaggtg caaaaaaaac aacagaggac taaatcgtgg
    10021 cttttgcaat acaattctta cgcctgtagg attagtaaga agacttatag tgccaacttg
    10081 aaactataaa tcatcggtac aatccctgat tttattgttg acatttcatt tatgccgact
    10141 atttatatgg tatacttgtc gaattatctt aaaggaagct cagattttct tatttttatt
    10201 gagaaaatga gatgacgcct tatgtctgta ttactacagg gagaagggag atgcttcatt
    10261 gcaaagggaa taatctatga acgcaataat tattgatgac catcctcttg ctatcgcagc
    10321 aattcgtaat ttattgatca aaaacgatat tgaaatctta gcagagttga ctgaaggcgg
    10381 aagtgccgtt cagcgggtgg aaacacttaa gcctgatatc gtcatcattg atgtcgatat
    10441 ccccggagtt aacggtatcc aggtgttaga aacgctgagg aagcgccaat atagcggaat
    10501 tattattatc gtctccgcta aaaatgacca tttttacggg aaacattgtg ctgatgctgg
    10561 cgctaatggt ttcgtgagta aaaaagaagg catgaacaat atcattgcgg ctattggagc
    10621 tgcaaaaaat ggctactgct atttcccctt ctctctcaac cggtttgttg gaagtttaac
    10681 gtccgaccag caaaaactcg actccttatc gaaacaagaa attagtgtca tgcggtatat
    10741 tcttgatggc aaggataata atgacattgc tgaaaaaatg ttcatcagca acaaaactgt
    10801 cagcacttat aaaagtcgcc tgatggaaaa attagaatgt aaatcactga tggatcttta
    10861 cacattcgca caacgtaaca aaatcggcta accacatgaa gtttttaccc tatatttttc
    10921 ttctctgttg tgctctttgg tcgaccatga gtttcgcaga cgaagattac atcgaatatc
    10981 gtggcatcag tagtaacaac cgtgtcacac ttgatccact acgtctgagc aacaaggaat
    11041 tacgttggtt agcgagcaaa aaaaatcttg tgattgcagt acacaagtcc caaacggcta
    11101 ccttgttgca taccgattcg cagcaacggg ttcgtggtat taatgctgat tatttaaatc
    11161 ttttaaaaag agcgttaaat atcaaattaa cactccggga atacgccgat catcaaaaag
    11221 caatggacgc gctggaagaa ggtgaagtcg atatagtgtt atcacattta gttgcttcgc
    11281 cgcctcttaa tgatgacatt gctgcaacca aaccattgat aattaccttt ccggcgctgg
    11341 taaccaccct tcacgactca atgcgaccgc ttacctcacc aaaaccagta aatattgctc
    11401 gggtagcaaa ttacccccca gacgaggtaa ttcatcaatc atttccaaaa gcaacaatta
    11461 tctcttttac aaatttatat caggcattag catccgtctc agctgggcac aatgattact
    11521 ttattggtag taacatcatt accagcagta tgatttcccg ctatttcact cactccttaa
    11581 atgtagtgaa atattataac tcgccgcgtc aatataattt tttcttgacc agaaaagaat
    11641 ctgtcattct taatgaagta ctcaatagat ttgttgatgc tttaacaaat gaagttcgct
    11701 atgaagtatc acaaaattgg cttgatacag gaaacctggc ctttctgaac aaaccattag
    11761 aactcactga acatgaaaaa cagtggatta agcagcatcc caatttaaag gtgctggaaa
    11821 atccttactc gcccccctat tctatgacgg atgaaaatgg ctcggttcgg ggcgttatgg
    11881 gggacattct taatattatt accttgcaaa caggtttaaa tttttctccg atcaccgttt
    11941 cacacaatat ccatgctgga acacagctta gccccggagg atgggatata atacctggcg
    12001 ctatttatag tgaagatcga gaaaataatg ttttatttgc tgaagccttc ataacaacgc
    12061 cttacgtttt tgtcatgcaa aaagcgcctg acagtgaaca aacattaaaa aaaggaatga
    12121 aagttgccat tccatattat tatgagctgc attcgcaatt aaaagagatg tatccggagg
    12181 ttgaatggat acaggtcgat aatgccagcg ctgcatttca caaggttaag gaaggtgaac
    12241 ttgatgctct ggtcgcgaca cagttaaatt cgcgttacat gatcgatcat tactatccta
    12301 atgaacttta tcattttctt attcctggcg ttccgaatgc atcgctttcg ttcgcttttc
    12361 ctcgcggaga accggaactt aaggatatta ttaataaagc actgaatgca attcccccaa
    12421 gcgaagttct gcgcctgacg gaaaaatgga ttaaaatgcc caatgtgacc attgacacat
    12481 gggacctata tagcgagcaa ttttatattg ttacgacatt atccgtttta ttagttggca
    12541 gtagcctttt atggggattc tacctgttac gctcagttcg tcgtcgtaaa gtcattcagg
    12601 gtgatttaga aaaccaaata tcattccgaa aagcactctc ggattcctta ccgaatccaa
    12661 cttatgttgt aaactggcaa ggtaatgtca ttagtcataa tagtgctttt gaacattatt
    12721 tcactgcgga ttactacaaa aatgcaatgt taccattaga aaacagtgac tcacccttta
    12781 aagatgtttt ttctaatgcg catgaagtca cagcagaaac gaaagaaaat cgaacaatat
    12841 acacacaggt atttgaaatt gataatggca tcgagaaaag atgcattaat cactggcata
    12901 cattatgcaa tcttcctgca agtgacaatg cagtatatat ttgtggttgg caagatatta
    12961 ctgaaacgcg tgatctaatt aatgcactcg aggtagaaaa aaataaagcg ataaaggcta
    13021 ccgtagcaaa aagtcagttt ctggcaacga tgagtcacga aataagaaca ccaataagct
    13081 ctattatggg cttcctggaa cttctgtcgg gttctggtct tagcaaggag caacgggtgg
    13141 aggcgatttc acttgcctac gccaccggac aatcactcct cggcttaatt ggtgaaatcc
    13201 ttgatgtcga caaaattgaa tcgggtaact atcaacttca accacaatgg gtcgatatcc
    13261 ctactttagt ccagaacact tgtcactctt tcggtgcgat tgctgcaagc aaatcgatcg
    13321 cattaagttg cagcagtacg tttcctgaac attacctggt taagatcgac cctcaggcgt
    13381 ttaagcaggt cttatcaaat ttactgagta atgctctcaa atttaccacc gagggggcag
    13441 taaaaattac gacctccctg ggtcacattg atgacaacca cgctgttatc aaaatgacga
    13501 ttatggattc tggaagtgga ttatcgcagg aagaacaaca acaactgttt aaacgctaca
    13561 gccaaacaag tgcaggtcgt cagcaaacag gttctggttt aggcttaatg atctgcaaag
    13621 aattaattaa aaatatgcag ggcgatttgt cattagaaag tcatccaggc ataggaacaa
    13681 catttacgat cacaatcccg gtagaaatta gccagcaagt ggcgactgtc gaggcaaaag
    13741 cagaacaacc catcacacta cctgaaaagt tgagcatatt aatcgcggat gatcatccga
    13801 ccaacaggct attactcaaa cgccagctaa atctattagg atatgatgtt gatgaagcca
    13861 ctgatggtgt gcaagcgcta cacaaagtca gtatgcaaca ttatgatctg cttattactg
    13921 acgttaatat gccgaatatg gatggttttg agttgactcg caaactccgt gagcaaaatt
    13981 cttccttacc catctggggg cttacagcca acgcacaggc taacgaacgt gaaaaagggt
    14041 taagttgcgg catgaactta tgtttgttca aaccgttgac cctggatgta ctgaaaacac
    14101 atttaagtca gttacaccaa gttgcgcata ttgcacctca gtatcgccac cttgatatcg
    14161 aagccctgaa aaataatacg gcgaacgatc tacaactgat gcaggagatt ctcatgactt
    14221 tccagcatga aacgcataaa gatctacccg ctgcgtttca agcactagaa gctggcgata
    14281 acagaacttt ccatcagtgt attcatcgca tccacggtgc ggctaacatc ctgaatttgc
    14341 aaaagttgat taatattagc catcagttag aaataacacc tgtttcagat gacagtaagc
    14401 ctgaaattct tcagttgctg aactctgtaa aagaacacat tgcagagctg gaccaggaga
    14461 ttgctgtttt ctgtcagaaa aatgactaaa tagcggctcc cacaatgttc aaatgtggga
    14521 gctatttacc agcacatctt acatttatga tgagaactcc tggcgaattt gttccccatg
    14581 ctggtcgagc gttgccgctc ccggcataac atgcgggtcc gcgcagccgc tgatttttat
    14641 cggattaccc ggcatcatta ttcccccggc ttcaatcaac atatttctcg cctgagtttg
    14701 tggcaattta atggcctcag ccacacttaa taacggcgcg acgggtacac caacttcatg
    14761 tattctggct aaccaaactt cagctgcctg cgtttttaac gtccgctcaa tatattgttt
    14821 aagaatagcc tggttttgta cgcgtaaaat attgctgcta aatcggggat cattaaccag
    14881 ttccgtaagc tccagtgcct ggcataacgc agaaaaaagc ttgtcattac cacaacaaat
    14941 cgtaatcggc ttatcctgag tattgaaaac atcaaaaggt gccatgtagg gatggcgatt
    15001 tcccagacgt tgtggtgact tcccagttgc gatatatgcc atcagaccat gctccagaaa
    15061 actcagcgtg gcatcaaaca tcgctatatc gacatgcgcc cctctctggc tcttttcgcg
    15121 gccataaagt gcactcacta ttccgctgaa taaatagaca ccgccgcata gatccgcaag
    15181 agatgtacca acgcgcactg gcggagcatc aggatatcct gtttccatca ttatcccgct
    15241 cattgcctga atgatggtat cgtaggcagg agcatctttt agcggaccgg tatgtccgaa
    15301 acctgacgat gaagcatata tgaggcgcgg gttgatttct tgaagcgttt cccatgaaaa
    15361 ccccagtttt tccattgtac ctgggcgaaa attctcagct aatacatcag cttgtttgag
    15421 catatttata aatatacttt tatcgtgatc attctttaaa tcaagaacca cactctcttt
    15481 gccatgatta ataaaactgt aatagagtga ctgtccatcc acatagggac caaatgtgcg
    15541 ggtatcatca ccatgacccg gcggctcaac tttaattacc cttgcgccca tattacaaag
    15601 aagttgagtt ccgaaaggtc cattaaggac atgtgtcata tcgataacta ataagccttc
    15661 aaacggccct ttgctttcat tatttgtcat ttgcttatgc cttgaaaaaa gccgaaggtg
    15721 aaaagacact tcggcattta tgtaaaatca ataacatgat taattatgaa accagtcgac
    15781 tgacataaat ccacaaggga gccgtgacga caaagcccag tacgctcaca gccaatgacg
    15841 ctgtaccagt acgggtgtag acattaaacc ggctggcaat aatgattccg gagaatgccg
    15901 gcggtaatgc gcctgccagt accatcatct gcagatgttc gctgttcaaa tgacatgcca
    15961 taccaacgag aagcagtgcc agtggcatca gaatcagctt caggaaggtg ttataagcaa
    16021 tttcggcact gaactcgaat ttatgtgcag ccagagtcaa ccccgcagcg aataccgcta
    16081 cccctgagtt agccttcgca atcagattaa aggttgggtc ccatgctgcc ggaattttta
    16141 ccccaaccaa caccaggatc gttgccagaa caggtgccca tactactggc tcctttgccg
    16201 cagaaattaa tgcgctcaga ttactattct tcttaccatc cgctcctgaa gaaggattca
    16261 gcaaatacag accaatagga atagtaattg cgttaacaat aatagaaata attgctacca
    16321 ctaaacctgt tgatacggaa tcaccataaa taggatcgag aactgcaaac cccaggaatc
    16381 caatggtagg tgaacctgca attaatgcac atacagctgc ttctgcatgg gtacgtttaa
    16441 aaaatttgta gcaaccgaac caggagaaaa agaaacatcc gacaataacc acaagtgata
    16501 caagggtcag acgagtgtcc gcaaaaatca tttccctgtt tgcccgagta atagatacaa
    16561 atagagccgc aggaagcgcg tagtttaata ccagtttatt aaatgcccga gcttgatctt
    16621 ctgaaaatgt ttctcgtctg ccgctaaaat aacccaacag catgattacg ataataggca
    16681 ataaatcgcc aataaaaaat gttagcataa tagtatttcc gataagggtc ccctcaccat
    16741 cgcataatga gttggcaaga ggagacgatg tcagtattta attaccagcg acttgttttg
    16801 ggttaagttt ggtaatatgg ccactttcag ttcctgctgc agggtcgatg accacattaa
    16861 taatggtcgg tttgcgcgac tgaataccgg tggttaaagc atgacgaagt tcatctgtcg
    16921 tggtgacgtt atagccaacg ccacgaaacg catccattaa tttgtcatac cttgcatggt
    16981 gcaacagatc cgttggtgat ggtgcaccag cgccactgag atcaacaccg tctcctctgt
    17041 agatgccgcc attattaaaa ataacgatcg tcaccggcag gttatatcga caaatcgttt
    17101 caatttccat cccactgaaa ccaaaagcac tatcaccttc aatggcgaca accggagaac
    17161 cagaagtcac gctagcaccg atggcatagc ccataccgat gcccatgaca ccccaggtac
    17221 cacaatccag acgacgacgt ggtttataca tatcaataat atttcgtgca ttatccaggg
    17281 tatttgcacc ttcattaact aaataaatat cctggttctc gcgcaatacg tcgcgcacag
    17341 cacttaatgc attaaagtaa tttaatggtt gagtatctgt acttaatttt tcatgcattt
    17401 tttgtgcatt ttgctgcttg tggatattta aaatatcgcg ccataccagt ggagtcgtaa
    17461 atgtgttttg tttcagttct gccagcatac cttgcatact ggatgcaata tcaccaacga
    17521 ctggcacagc aatggggcgg ttgctgtcaa tttcctgcgg ttcaatatcc agttgaataa
    17581 actgtgtatc tgccgcccat ccttttttac cgtgtgccaa taaccaattc agtcgtgcac
    17641 caacaagcat gacaacgtca gcatttgcca gggcaaacga acgcgcagct gccgcagaaa
    17701 gtggatgcgt atcttcaagg atccctttcg ccatagacat tggcaggaat ggaatctgag
    17761 cactttcaat aaattcacga agctgttcat cagcttgtga atacgccgcg cctttgccaa
    17821 ggataattaa tggccgttca gcttttgcta aaagcgaaat tgcgctagtg actgacttcg
    17881 ggcatggcaa taatgctggc gacggatttt caactttaac aatcgtggtt aacgcttcgt
    17941 ctttttccat cgtcgcggcc aggacatttg ctggcaaatc aagataaact ccgccagggc
    18001 gacccgatac agagacccgg atagcgcgtg ccaatgcaat gccaagatcc tgcggctgat
    18061 taacgcgaaa tgctgctttg gcatacggtt ttgccgcatt catttggtcc agctcttcat
    18121 aatcaccttg ctgtaggtcg acgatcgcgc ggtcgctgga gccgctaatc atgatcatcg
    18181 gaaaaccatt taccgttgcg ttggccaatg cggtcaaacc attgaggaat cctggcgcag
    18241 aaactgtcag gcagatcccc ggtttttggg taagaaaacc gcttgccgca gcggcatagc
    18301 ctgccgactg ctcatgacga aaaccaatat aacgaatgcc ttccgcctgg gcatggcgtg
    18361 ccatatccgt cacaggaata cctacaacac cataaatagt gtcaatatta ttctgtttta
    18421 atgcttcaac gatgatatgc ataccatctg tcatttgaag ttgatctgac atgattaata
    18481 acctcgaaat ttttataaat tgggagccag aagcccccgt taatatcaga tggcgtggtt
    18541 ttgcttcatt gcagcaattt catcgtcgct ataacccagc tcctgcaata cagcagcggt
    18601 atgttcacct aatagcggcg cagctttaat atccggcgta aaggcagaga atttcattgg
    18661 acaaccaacg gtcagatatt ttccacgcaa cggttgttcc acttcaacaa cactgccact
    18721 ttggcgcaaa gagggatcaa gtgaaatttc tttcatactt aaaaccggtg cacaaggaat
    18781 atcaaactga gtcaaatagg ccaccgcttc atgtttatca atagtgacag tgtatttttc
    18841 gatttcagca aaaatatcga aaatatgtgg ctgtcgtgca tgggctgtac tgtatgccgg
    18901 atcggtaatc cattctggtt tgccgatggc tttacaggtg ttttcccagt tttgctcctg
    18961 aatagtgaaa taaatatagg cgttaggatc ggtttcccag cctttacatt tcaggatcca
    19021 gccaggctga ccgccaccac ctgcattacc accgcgggga actgcatcac caaatgtacc
    19081 attcggatac tgcgggtatt cttccagata acccaattta tcgagacgct gctggtcacg
    19141 taatttcacg cggcaaaggt tcaatacggc atcctgcatt gacatggtga ctcgttgccc
    19201 acgccccgtt ttttcgcgat gcagcaaagc agcaagtaaa ccgatcagca aatgcattcc
    19261 ggtgttgctg tcacccaacg ctgcagcgct taccagcggc ggaccatccc aaaaacccgt
    19321 agtggatgcc gcgccacccg ctgcctgagc aacgttttca taggctttta cattcacata
    19381 aggcgaacac tcatcaaacc ctttgatcga accaaaaatc agacgtggat tgatttcttg
    19441 aatatgctcc caggtgaagc ccatgtgatc aatggcccct ggatgaaagt tctcgactaa
    19501 gatatcagct tcgcggatca gcttttccat tacctctttg ccttccgctg ttttggtatt
    19561 taactcaata gaacgtttgt tactgttaag catggtgaag taaagcgcat cgatatcagg
    19621 aatatctcgc agctggtgac gcgttacgtc accaacgccg ggacgttcaa ttttaataac
    19681 gtcagcgcca aaccaggcca gcatttgagt acaagatggg ccagattgca caccggtgaa
    19741 atcgagaact ttaattcctt gaagtggagt tgacat
//
LOCUS       DAPHKZ010000083        19568 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.083, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000083 DAPHKZ010000000
VERSION     DAPHKZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19568
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.083"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            105..1007
                     /locus_tag="RH288_003069"
     CDS             105..1007
                     /locus_tag="RH288_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4032104.1"
                     /translation="MANLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSAVSQS
                     LQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKNLRGLEQTINIVNKSELKKNFII
                     YGPQLISCSNNSMLIRCLRQDSSVEIECHDILMSAENAEELLVHRKADLVITQMPVIS
                     RSVICMPLHTIRNTLICSNRHPRITDNSTYEQIMAEEFTQLISKSAGVDDIQMEIDER
                     FMNRKISFRGSSLLTIINSIAVTDLLGIVPYELYNSYRDFLNLKEIKLEDPLPSIKPY
                     ISYNKSSLNNLVFSRFIDRLNECF"
     gene            1154..2374
                     /locus_tag="RH288_003070"
     CDS             1154..2374
                     /locus_tag="RH288_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDV4032105.1"
                     /translation="MSIYKIPLPLNILEAARERITWTLNTLPRVCVSFSGGKDSGLML
                     HLTAELARQMGKKICVLFIDWEAQFSCTINYVQSLRELYTDVIEEFYWVALPLTTQNS
                     LSQYQPEWQCWEPDVEWVRQPPQDAITDPDFFSFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQSLCNPLYNLMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKGIEVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKSKNYQRYNERI
                     KGKRQEWGILCNND"
     gene            2347..2976
                     /locus_tag="RH288_003071"
     CDS             2347..2976
                     /locus_tag="RH288_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDV4032106.1"
                     /translation="MGDTMQQRLTQDLTQFLASLPEDDRIKAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNDQLVPNDYNPNNVAPPEKKLLKKSIEIDGFTQPIVVTHTDKNALEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQYSRAWTVK"
     gene            complement(2977..4137)
                     /gene="ybdL"
                     /locus_tag="RH288_003072"
     CDS             complement(2977..4137)
                     /gene="ybdL"
                     /locus_tag="RH288_003072"
                     /EC_number="2.6.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-oxo-acid transaminase"
                     /protein_id="HDV4032107.1"
                     /translation="MTNNPLIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDG
                     PRYLQERLAHHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTLDD
                     VEFCQWLTQEHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     gene            4246..5334
                     /gene="hcxA"
                     /locus_tag="RH288_003073"
     CDS             4246..5334
                     /gene="hcxA"
                     /locus_tag="RH288_003073"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /protein_id="HDV4032108.1"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKR
                     AIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTA
                     KALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALS
                     DQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFKKVESFKA"
     gene            complement(5344..5541)
                     /locus_tag="RH288_003074"
     CDS             complement(5344..5541)
                     /locus_tag="RH288_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HDV4032109.1"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(5724..7829)
                     /gene="cstA"
                     /locus_tag="RH288_003075"
     CDS             complement(5724..7829)
                     /gene="cstA"
                     /locus_tag="RH288_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HDV4032110.1"
                     /translation="MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFSITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKDPKPTAKETP
                     YEPMPENVEEIVAQAKGAH"
     gene            complement(8010..8423)
                     /gene="entH"
                     /locus_tag="RH288_003076"
     CDS             complement(8010..8423)
                     /gene="entH"
                     /locus_tag="RH288_003076"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HDV4032111.1"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDT
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     gene            complement(8426..9172)
                     /gene="entA"
                     /locus_tag="RH288_003077"
     CDS             complement(8426..9172)
                     /gene="entA"
                     /locus_tag="RH288_003077"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HDV4032112.1"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(9172..10029)
                     /gene="entB"
                     /locus_tag="RH288_003078"
     CDS             complement(9172..10029)
                     /gene="entB"
                     /locus_tag="RH288_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis bifunctional
                     isochorismatase/aryl carrier protein EntB"
                     /protein_id="HDV4032113.1"
                     /translation="MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     gene            complement(10043..11653)
                     /gene="entE"
                     /locus_tag="RH288_003079"
     CDS             complement(10043..11653)
                     /gene="entE"
                     /locus_tag="RH288_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HDV4032114.1"
                     /translation="MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGE
                     HNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVT
                     ALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRASA"
     gene            complement(11663..12838)
                     /gene="entC"
                     /locus_tag="RH288_003080"
     CDS             complement(11663..12838)
                     /gene="entC"
                     /locus_tag="RH288_003080"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HDV4032115.1"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     gene            13213..14169
                     /gene="fepB"
                     /locus_tag="RH288_003081"
     CDS             13213..14169
                     /gene="fepB"
                     /locus_tag="RH288_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HDV4032116.1"
                     /translation="MRLAPLYRNALLLTGLLLSGIAAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLY
                     IGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
                     EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLDRLKALF"
     gene            complement(14173..15423)
                     /gene="entS"
                     /locus_tag="RH288_003082"
     CDS             complement(14173..15423)
                     /gene="entS"
                     /locus_tag="RH288_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HDV4032117.1"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRHFRQTPPQVTASDS"
     gene            15534..16538
                     /gene="fepD"
                     /locus_tag="RH288_003083"
     CDS             15534..16538
                     /gene="fepD"
                     /locus_tag="RH288_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HDV4032118.1"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAF
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAIVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     gene            16535..17527
                     /gene="fepG"
                     /locus_tag="RH288_003084"
     CDS             16535..17527
                     /gene="fepG"
                     /locus_tag="RH288_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HDV4032119.1"
                     /translation="MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALSAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            17524..18339
                     /gene="fepC"
                     /locus_tag="RH288_003085"
     CDS             17524..18339
                     /gene="fepC"
                     /locus_tag="RH288_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HDV4032120.1"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTANS"
     gene            complement(18336..19469)
                     /gene="fepE"
                     /locus_tag="RH288_003086"
     CDS             complement(18336..19469)
                     /gene="fepE"
                     /locus_tag="RH288_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
                     /protein_id="HDV4032121.1"
                     /translation="MSSLNIKQGSDAHFPDYPLASPSNNEIDLLNLISVLWRAKKTVM
                     AVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKSFTKLRVLDLDIKIDRTE
                     AFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNAS
                     KKKDEPSLYTSWTLSFTAPTSEEAQTVLSGYIDYISTLVVKESLENVRNKLEIKTQFE
                     KEKLAQDRIKTKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKAHVNDVNFTPFKYQLSPSLPVKKD
                     GPGKAIIVILSALIGGMVACGGVLLRYAMASRKQDAMMADHLV"
BASE COUNT         4693 a         5452 c         4967 g         4456 t
ORIGIN      
        1 ttaatcctga gttaagcaaa aaaacataat caataaaaat atatacgcaa aaaacattga
       61 ttaagtgaat atatcatgga agaaaaatat aaccggagta gtgtatggcc aatctctacg
      121 acttgaaaaa gttcgactta aatcttcttg tcatatttga gtgtatttac cagcatttaa
      181 gcattagcaa agctgctgaa tcactatata tcaccccatc agccgtgagc cagtcgttac
      241 aacgcttacg tgcgcaattt aatgaccctt tattcattcg ctcaggaaaa ggtatcgcgc
      301 cgacgacaac agggttaaat ctgcatcacc atcttgagaa aaatctcaga ggccttgaac
      361 aaacaattaa tatagtcaat aagtccgaac taaagaaaaa ctttattatc tacggccctc
      421 agctcatttc ttgctctaat aatagtatgc tgatccgctg ccttcggcaa gattcctctg
      481 tcgagattga gtgccatgat atcctcatgt cagcagagaa tgctgaagaa ctgttggttc
      541 accgcaaagc cgatctggtg atcacccaaa tgccagtgat cagccgttcc gtcatttgca
      601 tgccattgca tacgattcgc aatactctaa tttgtagtaa taggcatcca cgaattactg
      661 acaatagcac ttatgaacaa attatggcag aagagttcac ccaattaata tctaaatcag
      721 caggggttga tgatattcaa atggaaatag acgagagatt tatgaatcgc aaaatctcat
      781 ttcgtggttc ctctttgctg acaatcatta atagcattgc agttacagat ttactgggaa
      841 tagtccccta tgaactttat aattcctacc gtgactttct taatttaaaa gagataaaac
      901 tggaagatcc gttaccttca ataaagcctt acatttccta taataaatct tctttaaaca
      961 atctggtatt ctcacgattt attgaccgcc taaatgagtg tttttgatat ataacttcag
     1021 aaagctacta taactttcac ctatttattc acggcgcgaa tgaaaaataa aacactctgc
     1081 tttacagtgt ttactttata attaacagac ttatctcact gatcaccctg taacgttcag
     1141 agagcgtctt cagatgtcta tttataaaat tcctcttccg ctcaatattc tggaagctgc
     1201 acgagagcgt attacctgga cactcaacac cctaccccgc gtttgtgtct cattttctgg
     1261 cggcaaagac tctggtttaa tgctgcatct gacagccgaa cttgcccgac aaatgggcaa
     1321 aaaaatctgc gttttgttta tcgactggga ggcgcaattc tcttgcacca ttaactatgt
     1381 tcagtccctg cgcgagttgt acaccgatgt catcgaagag ttttactggg ttgcgctccc
     1441 gcttacgacg caaaattccc tttcacaata ccaacccgaa tggcagtgct gggaacctga
     1501 tgtcgaatgg gtacgtcaac ctccccaaga tgcgataacc gaccctgact ttttctcctt
     1561 ttaccagcca ggcatgacct tcgaacaatt tgtacgtgag tttgccgaat ggttttcaca
     1621 aaaacgtccg gcggcgatga tgatcggcat ccgtgcggat gagtcctaca accgttttgt
     1681 cgccatcgcc agtttaaata aacaacgttt tgccgacgat aaaccctgga ctacggccgc
     1741 accaggcggt catagctggt acatttaccc catttacgac tggaaagtgg ctgatatctg
     1801 gacctggtat gcaaatcatc aaagtctctg caacccactg tataacctaa tgtatcaggc
     1861 aggcgttcct ctgcgtcata tgcgaatttg cgaacctttt ggcccggagc aacgacaagg
     1921 attatggctc tatcacgtta tcgaaccgga tcgctgggct gctatgtgcg cacgagtcag
     1981 cggggtaaaa agtggcggca tttacgccgg acatgacaat catttctatg ggcatcggaa
     2041 aatcctcaag ccagaacatt tagactggca agaatatgca ttattgctgc tcaatagcat
     2101 gccggaaaaa acagctgagc attaccgcaa taaaatcgcc atttatttgc actggtatca
     2161 gaaaaaaggc atcgaggttc cacaaaccca gcaaggggac attggcgcga aagatatccc
     2221 ctcctggcgg cggatatgca aagttttact caataacgat tactggtgtc gggcattatc
     2281 atttagcccc acaaaatcga agaactatca gcgttataac gaacggataa aaggaaaacg
     2341 tcaggaatgg gggatactat gcaacaacga ttaacgcagg atttaacgca atttctcgcc
     2401 agcttgccgg aagacgatcg catcaaagcg attaatgaaa tccgcatggc gatccatcag
     2461 gtaagtcctt ttcgggaaga accggtagat tgtgttttgt gggtcaaaaa tgatcagctt
     2521 gtgccgaatg attacaaccc aaacaacgtg gcaccacccg aaaaaaaact gctgaaaaaa
     2581 tccattgaaa tagatggttt tacccaaccc attgtggtca cgcatacgga taaaaatgcc
     2641 ctggaaatcg tggatggttt tcaccgccat gaaattggta aaggctcatc atcgttaaaa
     2701 ttacgcttaa aaggttattt gccggtgacc tgtctggaag gtacgcgtaa tcaacgcatc
     2761 gccgcgacta ttcgtcataa tcgcgctcgt ggacgccatc aaatcaccgc catgtcggaa
     2821 atcgtccgtg aacttagcca gttgggatgg gacgataata aaattggcaa agagctggga
     2881 atggacagcg acgaagtgct gcgcctgaag caaattaacg gcctgcaaga gttgtttgcc
     2941 gaccgtcaat attcccgcgc ctggacggtt aaatagctaa agctggcgca ggcgttcagc
     3001 tgctgccagc aacgtcgatt ccttcttggc aaaacagaga cgaatcagtt tatgtgggaa
     3061 gggatcggcg caaaacaccg acagcggaat cgccgctacg ccgtgctcct gcgtcagcca
     3121 ctggcaaaac tcaacatcat ccagggtaga aaccgcgctg taatccacca gcaaaaagta
     3181 tgtaccttca cacggtaaaa tctccagccg gctttcattt aaagcattca ccagaatatc
     3241 gcgcttctgg cgataaaagt ccggtaacgc aagataatgc tcaggttctg cacgtagcat
     3301 atcagcaagc gccagctgtg ccggggtatt caccgaaaag gtcagatact gatgtacctt
     3361 gcgaatttcg gcgctgatgg gcgctggcgc aacacaataa cccactttcc agccggtcat
     3421 atgataggtc ttgccaaatg aagaaaccgc cactgcccgc tcacgcagct gcggatgcgc
     3481 cagcacactg gcatggccct gttgtgaaaa gttgatgtgc tcgtagactt catcgctaat
     3541 gacaaaaatc tcgtgcccgg cgatcgcctg ccacaaagcg gcgaaatcag cctgctgcca
     3601 gacagttgca ctggggttat gcggagtgtt gaggatcacc agtctggtgc gctcgcttaa
     3661 taatgcggca aattcctgcc agtcaacgcg aaaatgcggt ggttgcagtg ccatacgctt
     3721 cactattccc ccagaaagcg cgatggcggg ggcgtaactg tcatagctgg gatcaaaaca
     3781 aatcacttca tcgccattgc gcaccagtgc ggtaatcgcc gcgtataacg cttccgtcgc
     3841 ccctgccgtt acggtgatat cgctatcggc atctggttga tagccataca aacgttccgt
     3901 tttctgagca atcgcctcgc gcaaggcctg cacgccggtc atgggcgcgt attggtttgc
     3961 cccctgtgca acgtggtgcg ccagccgctc ctgtaaatag cgcggaccat caaaatcagg
     4021 aaagccttgc gacaggttaa tcgcctggtg ttgctgcgcc agcgcgctca tctgggtgaa
     4081 aatagtggtg ccaagttgtg gaagtttgct ttgtggaatc agagggttat ttgtcatttt
     4141 tattgtacct gacgaagttg cgtgttgaag gcactataac acgatgctag tatttggcaa
     4201 tcaagacgtt tagatgtcta aataaaacaa taaggacaac acaacatgcc tcacaatcct
     4261 atccgcgtgg tcgtcggccc ggctaactac ttttcacatc caggaagttt caatcacctg
     4321 cacgattttt tcactgatga acaactttct cgcgcggtgt ggatctacgg caaacgcgcc
     4381 attgctgcgg cgcaaaccaa acttccgcca gcgtttggac tgccaggggc aaagcatatt
     4441 ttgtttcgcg gtcattgcag cgaaagcgat gtacaacaac tggcggctga gtccggtgac
     4501 gaccgcagcg tggtgattgg cgtcggtggc ggtgcactgc tcgacaccgc gaaagccctc
     4561 gcccgccgtc tcggtctgcc gtttgttgcc gttccgacga tcgccgccac ctgcgccgcc
     4621 tggacaccgc tctccgtctg gtataatgat gccggacagg cgctgcatta tgagattttc
     4681 gacgacgcca attttatggt gctggtggaa ccggagatta tcctcaatgc accgcaacaa
     4741 tatctgctgg cggggatcgg tgacacgctg gcgaaatggt atgaagcggt ggtgctggct
     4801 ccgcaaccag aaacgttgcc gctaaccgtg cgactgggga tcaataatgc gcaagccatt
     4861 cgcgacgtct tgttaaacag tagcgaacag gcgctgagcg atcagcaaaa tcaacagtta
     4921 acgcaatcat tttgcgatgt ggtggatgct attattgctg gtggtgggat ggttggtggt
     4981 ctgggcgatc gttttacgcg tgtggcggca gctcatgccg tgcataacgg tctgaccgtg
     5041 ctgccgcaaa ccgagaagtt tctccacggc accaaagtcg cctacggaat tctggtgcaa
     5101 agcgccttgc tgggtcagga tgatgtgctg gcgcaattaa ctggagcgta tcagcgtttt
     5161 catctgccga ctacactggc ggagctggaa gtggatatca ataatcaggc ggagatcgac
     5221 aaagtgattg cccacaccct gcgtccggtg gagtccattc attacctgcc agtcacgctg
     5281 acaccagata cgttgcgtgc agcgttcaaa aaagtggaat cgtttaaagc ctgacgtaca
     5341 aatttagcag cagcgcgcgc cgccttttcc accgtagcgc gcgtcctgcc gctcacggaa
     5401 aaactcttcg taggtcatcg gcgtttgatc gggatggtta acccgcatat gttcgacata
     5461 gttgtcgtaa tcaggcatac caatcatcag cttcgccgcc tgacctaaat attttccggc
     5521 ttttgccagt gaatcaaaca tcttggcctc cgctaaccat gttgctgaaa gagtgccgga
     5581 tgcggcgtga acgccttatc cggcctacaa atgctatcaa cgcgctcggt cagtcccctc
     5641 gccccaccgg ggagagggtt agggtgagag ggaaccctgg gcactaagcc aacattcgcc
     5701 aacatccccc cctcactctg actttagtgt gcgccttttg cctgcgccac gatctcctcg
     5761 acattttccg gcattggttc atacggcgtt tctttcgccg ttggcttcgg atctttcaat
     5821 gccgcaagtg ccgtcttaat cgagaacagt gccagaacca ccacgaccac cataaagaag
     5881 atggttaacc cggcatccag acggttgttg aacaccagtt gcgccagctg tgactcagta
     5941 tactgcgacg gaatattgcc gctgtcgatc attgcctgga acttattagc aatggccagg
     6001 aagccgactt tcgcatccgg gctaaacgct ttctgccagc ctgcggtcag ggtacaaatc
     6061 agcagccagg ccgttggtac cagcgccacc caggcgtaac gttgacgttt catcttgaac
     6121 aacaccacgg cacagagcat cagcgccatc cctgccagca tctggttggc aataccaaac
     6181 agcggccaca gagtgttaat gccgcccagc ggatcgacca cgccctgatg gaggaagtag
     6241 ccccacgcca gtacgcacag cgctgttgcc agcaggttag caggcagtga atcggtccgc
     6301 ttcaggccag gagacaccac gcccagcaga tcctgcaaca taaagcgcgc agcacgcgta
     6361 cctgcatcca ccgccgtcag aataaacagt gcttcaaaca aaatggcgaa gtgataccag
     6421 aacgccacat ccatcatgcc gcccagcgcg ccgtgcagaa tgtaggccat ccccaccgcc
     6481 agcgtcggcg caccgcccgc acgggaaatg atcgactgtt cacccacttc gctggcaatc
     6541 tggtttagcg tatctggtgt aatgctaaag ccccagctac tcaccacctg cgcggcagaa
     6601 gcgaccacat ccgccgtccc tgccggagcc agcaccgcca tcgggctgtt catggcaaaa
     6661 tacacgcccg gatcgatgat acaggcggaa accagcgcca taatcgccac gaaggattcc
     6721 attaacatcc caccgtagcc gataaagcac gcctgccctt cgttcgccag catcttcggc
     6781 gtggtcccag aagagatcag cgcatggaag ccagacaccg cgccacaggc gatggtgata
     6841 aacaggaacg ggaacaggtt accggtccat accgggccag tgccatcgac aaatttggtc
     6901 agcgcaggca tggtcagcgt cgggcgcata atcaaaatgc ctaccgccag accgacgata
     6961 gtcccgattt tcaggaaggt agagaggtag tcacgcgggg ccagcagtaa ccacaccggc
     7021 agcaccgccg ccacaaaacc gtaacccacc agcatccagg tcaactgcac gccggtaaag
     7081 tcaaagtacg gtgcccaggt cggactttct gccacccagc cgccagagat aatggcgaaa
     7141 atcaggaata ccagaccgat gaccgacact tcgccaatac gccccggacg cagatagcgc
     7201 aggtagatcc ccataaacag cgccagcgga atggtgaacg caacggtata tgttccccac
     7261 gggctatgag tcagggcttt caccacgatc atcgccagca ctgcaaggat aatgaccatg
     7321 atcataaagc aggccaccag cgcaatcacc ccggcggttg gccccatctc ttctttgacc
     7381 agctcaccca gcgagcgacc gtcacggcgc gtagaaacaa acagcaccat gaaatcctgc
     7441 accgcaccgg cgagaaccac cccagcgagc agccagatca tccccggcag gtagcccatt
     7501 tgcgccgcca gtaccggccc caccagcgga cctgctccgg caatggccgc aaaatggtga
     7561 ccgaacagca ctttcttgtc cgtcggcaca tagtccagcc cgtcgttatg gcgcaccgct
     7621 ggcgtcatac gcgtcgggtc aaccgccagc acatttttgg cgatatacag cccataaaaa
     7681 cggtaagcga tcagatagat acagaccgac gccaccacaa tccacagcgc gttgatctgt
     7741 tccccacgat ttaaagcaat gtatcccaga gcaaatgctc ccattacaga gagcactgtc
     7801 cagacgaggt atttccctga tttgttcata gttgttatcc gtgtgcgtgt ccatagagat
     7861 gttacatttt gtttctataa catctttgta caatttaaca acacagcaac catgtaaatc
     7921 ggagttgaaa ccaatattta acttaacaat gttaactcga tcactccgtt aaccgagttt
     7981 tcctgcaatc tcatctaatt ctgtcgggtt catcccaaaa ctgccgtacc cagccgacaa
     8041 gtgcagcaac gccgcccctg ttcatcgaaa acgacgattt cccagctctg attttgccga
     8101 ccaagatgca gcggctggca gacgccgcgt acctttccct cagacaccgg gcgatggtgt
     8161 gttgcattaa gttctgtgcc taccacacac tgtccgtcgc gggtcatcat aaatccggcc
     8221 atcgatccca gcgtttccgc cagcgccgcc gacgcgccgc catgtagtaa accgaacggc
     8281 tgatgagtac gggtatcaac cggcatttcg gcttccagca catcatcgcc cagacgggta
     8341 tacacaattc ccagatgcgc caccattgtg ttatcgctgg tggcgttcag ttcgtcgagc
     8401 gttaaatggc gtttccagat catgcttatg cccccagcgt tgagccgcca tcgaccacaa
     8461 tatcctgtag ggtaatatgg ctggcgaggt cagaggcgag gaacaaaatc gtgttggcga
     8521 tctcttgtgg acgggcgatt ttccccagcg gaatgccgag tttaaactgc tcgccaaagc
     8581 cgcgaatacg ctgttcttcg gcgtcatcgc tcacccacag cgtgcgttgc atatcggtgt
     8641 cggtggagcc aggcgaaacc acattacagc gcacgccgct acccgccagt tccagcccga
     8701 cgctcaacgc caggcttttc agcgccgctt tcgatgcgcc ataagcactc atgccaatac
     8761 gcggcgtgtg cgcggcgtcg gacgccacag tgacaatcgc cccgccccgc tgacggcgaa
     8821 actggttcat ggtttgctgg aacaggttaa acgcaccgcc gacgttaacc gcaaaagtct
     8881 gctgccagtc ctctttactg agctgatcgg tcgcgcccat gcgtaaaatt cccgccgcat
     8941 tgaccagcgc gtccagtcgc tccgtttcag ctaacagtcg ctgacacact tgcgcgacct
     9001 gcgcagcgtc ggcaacatcc atcacttcgg tcgcaaaggg atattgctcc tgagtgaacg
     9061 cttgatcaaa acctgtaact ttcgctcccg cctcaacaaa cgccagcgcc gtggcgtagc
     9121 cgataccttt acctgcgccg gttacccaga catttttacc gctgaaatcc attatttcac
     9181 ctcgcgggag agtagcttcc accaggcgtc gatggtcggg tttttcgcca gcatgacaaa
     9241 gtcgatatca ccatgcactt tgcgccagcg cgccgccagc gccatcatgc gcaccgaatc
     9301 cagaccgtag tcgatcaggt tgtcgtcatc gaacggttca tcggactcgt ccagcaacgg
     9361 caggatcacc tcacgcagcg ccgctttgct ggcggggata ggtgctggca gtaattcttc
     9421 agtcatcacc acccggccag aacgtccggc cacatatttc agcgacatca aatgctcgtc
     9481 acggctgaaa tcggccagcg catccgccac cataaacggt ttaatatcgc gcataaatgc
     9541 gtcggttgcg gtggtcatac agccaatgtg ggcatatacc ccggtaataa tcagctggtt
     9601 acgtccactc tctttcagca tttgctccag cggagaacga tgaaacgcgc tgtagcgcca
     9661 cttcaccagc accgtgtcgt cggcatctgg cgtcaggcga tccaccacct tttgctgttc
     9721 cggcgagcgg gtcaggcccg gcccccacat atcattcaac agcgcccgat cttcatcgct
     9781 ctgctctttc ggctgggcgg tgtaataaac cgggatattg tgctgtttgc agtagtcgcg
     9841 cagcgcagca atattcgcga tcacctgctc catcatcggg cagttctcgc cccagaagct
     9901 gacaaaatag tcctgcatat catggattaa caacgcggca cgttgcggtt caaaggccca
     9961 gtcaacttta ttctgcggaa tatcgtgaga ctccggcagt gcgtaagcct gtaattttgg
    10021 aatagccatc gtgttctctc cttcaggctg atgcgcgtga cgccagccac tgacgtaatt
    10081 gttttttatc gactttcccg accgccgtca gcggaagtga atccacacac tccacgcgat
    10141 ccggtaattt aaattcggca ataccctgtt cacgcaggaa acgacgcacc tgcaccgcgc
    10201 gcagcggctc ttttaccacc agataagcgc agcttttttc gcccatcagc tcatcttcca
    10261 tgctcaccag tgcggcgtag atcaccgccg ggtggcgcag cagcaggttt tcgatctctt
    10321 cggcagcgat cttctcgccg ccacggttaa tctgatcttt ctcgcgcccc tgcacggtga
    10381 tgtaaccctc tggatcaata gagatcagat cgccggaaca gtaaaaaccg ttggcatcaa
    10441 aggcgctggc attgtgctgt ggacttttgt aatagccgcg gaaggtgtac ggcccgcgcg
    10501 tcatcaggcg tccgacttcc ccttgcggca gtggatttcc ttcggcatcg gcaacccata
    10561 cttcgtcatc cggacacatt gggtaaccct gggtatggat aattttctcc gcgctatcat
    10621 caagtcgggt gtagttcacc agcccttccg ccatgccaaa cacctgctgc aactgacagc
    10681 caatctcagc gggaatacgc gccgcaaggg tggcagaaag acgtgcgccg ccgacctgta
    10741 acagtttcag cgaggcaagc tgcgcccggc tttcgccttc gatcagcgcc tgcaaccaca
    10801 ggctgactgc gggtggcacc agcgcggtaa cgttaacctg atgtttttca atcaatggga
    10861 aacagagcgt ggcgctggga tcggccgcca gaacaaccgt tcctccggca agaaagacgc
    10921 ccagcgatcc tggcgaactc atggcgtagt tatgagccgc cgggatcgcg cacaggtagc
    10981 gtgtctgttg tgtgaactga caaatctcga cgctacgacg cacgctgtag tagtagtcgt
    11041 tatgagtgcg cgggatcagt ttcggtgtgc cggtggtgcc accggaaagc tggaaatagg
    11101 ccacttcatc agcaggtgat ggcgtggcag taaaatcctc agccggatgg ttaatcgcat
    11161 cctgcaagtt atgctcaccg ctgtcgttga gcagttgcac cacgcgaatg gaggaatgtt
    11221 ctgtgacgaa agtattgagg aaatcatccc cgctaaacag cgcatgttgg cgatcggcaa
    11281 tcagcaatgc gggttcaatc tggctggcat aggcgttcag ttcactacgc tgatggctga
    11341 acaacgccag caccggcgca acgcccagtt tcagcagcgc gaaaaaggta atatacaatt
    11401 cagcgacgtt acccagttgt accagcgcgg tttcaccagg tttaatgccc tgacggcgta
    11461 aactacacgc gaggttatcc gccgcctgat tcagctcccg ataactcaac tgtcgctcgc
    11521 cgtcgataac cgcgatgctg tcactcgcag catgtcgcgt cagaatgtcg gtcagcggca
    11581 aatcctgcca gtagcctttt tcccgatagc gacgggcaaa ctcttccggc cagcgggtga
    11641 atggaatgct catcctcgct ccttaatgca atccaaaaac gttcaacatg gtagaaagtt
    11701 tgacgcctgt ttcgcgccac tcacccaacg gtgacgacgc aggcacaatc cccgctccgg
    11761 caaacagacg cacctgattt tcccgcagct tcgcgcagcg gatggtcacc acccattcgc
    11821 cgttaccttc gctgtcacac caacccacaa tgccgccaaa cagttcgcgg tcgaacggtt
    11881 ccagttcagc aataacctgg gtcgcggcct gatgcgggaa accgctcagc gcgggggtcg
    11941 gatgcagcag acaggccaga gtcagtgcgt tttcttgcga attcgcttta ccttcaaagg
    12001 gagttgcgag atgccacagc gtcggcgtgg tgatcagctg tggagaagaa ggaacgtgta
    12061 actcactact gcgttcgcgc agtacctctt tcatcgcctg agtcaccagt tcatgttcat
    12121 ggcgatcttt ttctgacgcc agcagacgat tacctgcttc gcgatcgagc acttcatccg
    12181 gctgacgacg cgcggaaccg gctaacggaa tggagctaaa acgctcgccg tctttacgta
    12241 gcagcagttc cgggctggcc cccagcagga cgccaccatc agccagcgga acatggaagt
    12301 tgtaactaac cgggttttgc gcaatcaacc gttccagcaa tacgccacta tcaatggcgg
    12361 cgtcagtggt gatatcaatc aaccgtgaca acaccacttt gtcgacctgc ggcgtggcgg
    12421 taagtgcggc ggcgcgggca accatctgtt caaacgtggt ttgctccgga attgcctggc
    12481 gttccaccac attcagcgac tggctgcggg tgaaacggcg tgcggaagct tgtttttcct
    12541 gacgggagaa cgactgccag gattcaggaa tatacagcga cgaaggctga cgtggatcga
    12601 agggaatcgc cccgaccatc accggatttt tgatgccctg cgctttggca tcggcaaaca
    12661 gcgcggcgag tttttgctgg aagggactgt cgggcgaatc cccgttcaca gccggttcat
    12721 cgaagcgggc gaaacatcct gacgtcgtaa aactgcggta cggcgacata aagaaaaagc
    12781 gattgggcgc aagtgttgcc atggtctgct gtacttcctc agccagtgac gtatccatat
    12841 catcctccac aaaatgataa aggctttaat aatgattatc atttatattt tcggtcgcta
    12901 acctaaaagc aaacgcgcac tatgtcaact cttgaggtaa cgcaatctgc aactcggggt
    12961 tgcatctggt tgtggttaca atgaaaatga gaagcattat tgatggattc gcataagcgc
    13021 aatgtgatgt cctgcgccgt tctgccccct ctcccttcca gggtgagggc tggggtgagg
    13081 gttaatgttc gcaccagtgc tggctgttcc cctcacccta accctctccc caaaggggcg
    13141 aggggacgga ttgtgcgctt tgtcgaattt gtcattacgc ccttaacctt attaataaca
    13201 ggaagctgat ttgtgagact cgccccgctc taccgcaacg cccttctatt aacaggactt
    13261 ttgctttcag gaatagccgc agttcaggcc gctgactggc cgcgtcagat tactgacagc
    13321 cgtggcacac atacactgga aagccagccg cagcgtattg tttccaccag cgtcaccctg
    13381 accggctcac tgctggcgat tgatgctccg gtgatcgcca gcggcgcgac cacgccgaat
    13441 aaccgcgtcg cggatgacca gggcttttta cgccagtgga gcaaggtggc gaaagaacgc
    13501 aaactgcaac ggctctatat cggcgaaccg agcgccgaag ccgttgccgc gcaaatgccg
    13561 gatctgattt taattagcgc aaccggcggg gattcggcgc tggcactgta tgatcagctt
    13621 tccaccatcg ccccgacatt aatcatcaat tacgacgaca aaagctggca gtcgctgtta
    13681 acgcaacttg gcgaaattac cgggcatgag aaacaagcgg cagagcggat tgcgcagttt
    13741 gataagcaac tggcggcggc gaaagagcaa atcaaattac cgccgcagcc ggtcactgcc
    13801 attgtctata ctgccgctgc acacagtgcc aatctctgga cgccagaatc agcacaaggg
    13861 cagatgctgg aacaactcgg ctttacgctg gcgaagttac ccgcagggtt aaatgccagc
    13921 caaagtcagg gtaaacgcca tgacatcatt cagcttggtg gggaaaatct ggctgcaggg
    13981 ttaaatggcg agtcactatt cctgttcgcc ggtgatcaga aagatgccga tgctatttat
    14041 gctaatccgc tgctcgcgca cctgcctgca gtacaaaaca agcaggttta tgcgctggga
    14101 accgagacgt tccgtctgga ttactacagc gccatgcaag tgctggatag gcttaaggcg
    14161 ctgttttaag cattaactgt cggacgctgt cacctgcggc ggcgtctggc gaaaatgtcg
    14221 caactccacc agcaccagca ataacaacac gccgataatc aacaaaccaa aaccgctcgc
    14281 gcttgcggaa gcaaccggtg tcatcatcgc gcccaaacca cccagcagcg ccgcgcctat
    14341 ggcatcgccc gtcacgttct gcgccgtcca caaaccgtta atccgcccta acatcgcttc
    14401 cggggtttgc gtttgcagca ttgtgtattg cagcaacgag ctgaccgcac tcaaccagcc
    14461 gaacagcgcc agacaaacca cgcctaaaat ccacatcggc atcaggccaa acagaccaat
    14521 ggcgaggaac gatcccagcg tggagagcag catcaataac cctggtcgcg cactatgtgc
    14581 cagcttcccg ctggttaacg caccaatagc cgcgccgagc gggatcgccg cgtagagaaa
    14641 accaatctgt gccgctgaca tctgccagtt gtcagccagc gccggataca gtacccgcac
    14701 cgcgctcgcc atcgtcaata aaccacccag cagcgcaatc ccgcccacca gcgggctggc
    14761 aagcagaaaa cgaaatcctg ccagtaatga tttcaacgga tgctcacgcg gctgcggtgg
    14821 cggtggcaac gccggaaggc ttaacaacgg tagcagggta ataaacgtgc ccgccgccgc
    14881 cagcccgtag ttccaggcta cgccaccggt cgccagcaat aaaccgccaa tcatgggcga
    14941 aatcaccgac cccagacgca cggtcaacat ggtgatcgcc ccggcctgca ttaagttttc
    15001 acgccctacc agtgctggtg tcgccgccaa tagcgccgta acgccaagcg atgcgaaaaa
    15061 accatcccat aaaccaagta aatagattgc cagcaatgac ggctccggca gcagtgcatt
    15121 aaggcacagt ccaatgaagc caatgccaca ggtgccgcgc gccagcaaaa tcactttttt
    15181 gcgctcatag cgatccgcca gcacaccgcc gaccatcagg ccaacaaaca tcgcgccgcc
    15241 ggtcagcgtc accgaaagcc ccacctgcca ggtggaatgt gtcatcatct ggatctgcac
    15301 cggcaccgcg acgccgagca aacccagaga cacaattgag atgaaacgag cgaggaatac
    15361 tgcgcgaaac gccgggtgcg ttttcaacag gctgaggtta agcagccagg attgtttatt
    15421 cattacaatg ccttgccatc aaatatttta aatacctatt cttaggctgc acatgctaac
    15481 atatccaaat aagatcgata acgataatta atttcattat catggaagtt cgtatgtctg
    15541 gttctgttgc cgtgacacgc gccattgccg tgcccggatt gctgttatta ctgattatcg
    15601 cgacggcatt aagcctgctc attggggcaa aatcactccc cgcttccgta gtgctggagg
    15661 ccttctccgg cacctgccag agcgccgact gcaccatcgt gctcgacgcg cggctgccgc
    15721 gtacccttgc cggtttactg gcaggcggcg cgcttggcct tgccggggcg ttaatgcaaa
    15781 ccctcacccg aaacccactt gccgaccccg gcttgcttgg cgtgaacgcc ggagccagct
    15841 ttgccattgt gctgggtgcg gcgctgtttg gttactcttc cgcgcaggaa caactggcga
    15901 tggccttcgc cggggcgctg gtggcctcat tgattgttgc ctttaccggc agtcagggcg
    15961 gcgggcagtt aagtccggtg cgtttaaccc tggcgggcgt ggcgctggcg gcggtgctgg
    16021 aaggactgac cagcggcatc gccctgctta atcctgacgt ctacgatcag ttgcgtttct
    16081 ggcaagccgg ttcgctggat attcgcaatc tacatacctt aaaagtggtg ctgatcccgg
    16141 tgctgatcgc cggagcaact gcgctattac tgagtcgcgc gctgaacagt ttgagcctcg
    16201 gcagcgacac cgcgacggcg ctgggcagtc gcgtggcgcg cacacagttg attggtctgc
    16261 tggcgattac cgtgctttgt ggtagtgcga cggcaatagt tggcccgatt gcctttattg
    16321 gcctgatgat gccgcatatg gcgcgttggc tggtgggtgc cgatcatcgc tggtcgctgc
    16381 ccgtcacgct acttgctacc cctgccctgc tgctgtttgc cgatatcatc gggcgggtga
    16441 ttgtgcccgg cgaactgcgc gtttctgtgg tcagtgcgtt tattggtgca ccggtgctga
    16501 tcttcctcgt gcgacgtaaa acgcgaggtg gtgcatgatt tacgtctctc gccgattact
    16561 catcacctgt ttgctgctgg tttccgcctg tgtggttgca ggtatctggg gattacgcag
    16621 cggtgccgtc acgctggaaa cctcgcaggt attcgccgcg ctgatgggcg atgcgccgcg
    16681 cagtatgacg atggtggtca ccgaatggcg tttaccacgc gtgctgatgg cgctgttgat
    16741 tggcgcagca ctgggcgtca gtggcgcgat ttttcagtcg ctgatgcgta acccgctcgg
    16801 cagccctgac gtaatgggct ttaacaccgg ggcgtggagc ggcgtgctgg tggcgatggt
    16861 gctgtttggt caggacctga cggctatcgc gctgtcagca atggtgggcg gcattgtcac
    16921 ttcgctgctg gtctggctgc tcgcctggcg caacggcatc gacacctttc ggttgattat
    16981 tatcggtatc ggcgttcgcg ccatgctggt ggcctttaat acctggctgt tgctgaaagc
    17041 gtctttagaa acggcgctaa cagcaggttt gtggaatgcc ggatcgctca acggcctgac
    17101 gtgggcaaaa acctcgcctt ccgcacccat cattatattg atgctcattg ccgccgcctt
    17161 actggtacgc cggatgcgct tgctggaaat gggcgatgat accgcgtgtg cgctgggcgt
    17221 cagcgtcgaa cgttcgcgtc tgttaatgat gctggttgca gtggtgctta ccgctgcggc
    17281 aacagcgctt gccgggccga tttcctttat tgctttagtc gcaccgcaca ttgcccgacg
    17341 cattagcggc accgctcgct gggggctaac ccaggcggcg ctatgcgggg cgctgttact
    17401 gctggcggcc gatctctgcg cccaacaact gtttatgccg tatcaacttc cggttggcgt
    17461 cgttaccgtc agcctcggcg gtatttacct tatcgtcttg ttaattcagg agtctcgcaa
    17521 aaaatgaccg aatcagtagc ccgtttgcgc ggcgaacagt taaccctggg atatggcaaa
    17581 tataccgttg cggaaaatct gactgtagaa atacctgatg gtcacttcac ggcaattatc
    17641 gggccaaatg gctgcggtaa atccacgtta ctgcgtacct taagccgcct gatgacgcct
    17701 gctcatgggc atgtctggct ggatggcgag cacattcaac attacgccag taaagaggtt
    17761 gcacgccgga ttggtctgtt ggcgcaaaat gctaccacgc cgggcgatat caccgtgcag
    17821 gagctggtgg cgcgtggacg ttatccgcat caaccgctgt ttacccgctg gcgcaaagag
    17881 gatgaagaag cggtaacgaa agcaatgcag gccacgggaa taactcatct ggcagatcaa
    17941 agcgtggata ccctttctgg cggacaacgc cagcgagcgt ggatcgcgat ggtgctggcc
    18001 caggaaacgg caattatgct gctcgacgaa cccacgacct ggctggatat cagtcatcag
    18061 attgatttgc tggagttgtt aagcgaactg aaccgcgaaa aaggctatac cctggcggcg
    18121 gtgctgcacg atcttaatca ggcctgtcgt tacgccagcc atttgattgc attgcgggaa
    18181 gggaaaattg ttgctcaggg agcgccgaag gagattgtca ctgctgaact gattgagcgc
    18241 atttatggtc tgcgctgcat gatcattgac gatccagttg ccggaacgcc gcttgtggtg
    18301 ccgctcggac gaacggcacc ttcaaccgca aatagttaaa ctaagtggtc tgccatcatg
    18361 gcatcctgtt ttctggatgc catcgcatag cgcaacagca cgccaccaca agccaccatc
    18421 ccgccgatca acgcggaaag gatcacaata atcgccttac ccggaccgtc ttttttcact
    18481 ggcaatgacg ggcttaactg atatttaaac ggcgtaaaat tcacatcgtt gacatgtgct
    18541 tttgttaatt gctcgacaag atactgccga ttacgtaatt caccgttcag ttccgcaacg
    18601 tcagtgaccg ctttttctat ttccagtttg cgttcaatac cgtctgcacc gagagaaata
    18661 gaaaaatcgg ggtcatcttt aacggcctga ccattactgt aaacgggctt tttaattcct
    18721 gccgcgttgg caatgtcgag tgaataattg aggcgctgaa tgtttgcatc aagttgattt
    18781 ttcgttttaa tgcgatcctg agccagtttt tctttttcaa actgggtttt gatctccagt
    18841 ttattacgga cgttttctag cgactctttc accaccaacg tagagatata atcgatatac
    18901 ccgctcaaaa cggtctgcgc ctcttcactg gttggcgcgg taaaacttag cgtccaggag
    18961 gtatacagtg acggttcatc ttttttctta ctggcattgt catcaaccgc tttcattttt
    19021 tcgctcaatg cgacaattgc gcgatgcaaa tccagttcgt cgattttcgc ctcttttaat
    19081 tggtccatca cataaggtga tgaacgcagg tactcttcca gcaagctaac cgactgaaac
    19141 ttcttgataa acaggttaaa tgcttctgta cgatcaattt tgatatccag atccagcaca
    19201 cgaagcttag tgaatgattt ctccaactct tgccactgaa caggttctgg aggcgtgaca
    19261 accgccgcgc tggtccattt ttgcggcagg atgaaagaga tcagcaagcc tgcgcaggca
    19321 aacgcaaaaa cgaccgccat gaccgttttt ttggcccgcc ataaaactga gattagatta
    19381 agtaaatcaa tttcattatt actgggcgac gccagaggat aatcgggaaa atgagcgtca
    19441 cttccctgtt taatattcag tgatgacatg gggtataacc tgaaaatgag tccaataggg
    19501 ggaaatctcc acggcgctca ctttaccagt tggtgataat tatccgaagc tgaagtttgt
    19561 aaattcct
//
LOCUS       DAPHKZ010000084        19054 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.084, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000084 DAPHKZ010000000
VERSION     DAPHKZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19054
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.084"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            221..505
                     /gene="traQ"
                     /locus_tag="RH288_003087"
     CDS             221..505
                     /gene="traQ"
                     /locus_tag="RH288_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     chaperone TraQ"
                     /protein_id="HDV4032122.1"
                     /translation="MISKRRFSLPRLDITGMWVFSLGVWFHIVARLVYSKPWMAFFLA
                     ELIAAILVLFGAYQVLDAWIARVSREEREALEARQQAMMEGQQEGGHVSH"
     gene            492..1037
                     /gene="trbB"
                     /locus_tag="RH288_003088"
     CDS             492..1037
                     /gene="trbB"
                     /locus_tag="RH288_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly thiol-disulfide isomerase TrbB"
                     /protein_id="HDV4032123.1"
                     /translation="MSLTKSLLFTLLLSAAAVQASTRDEIERLWNPQGMATQPAQPAA
                     GTSARTAKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYGFSV
                     FSYTLDGQGDTAFPEALPVPPEVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGATDA
                     AGFMARVDTVLQMYGGKKGAK"
     gene            967..1308
                     /gene="trbJ"
                     /locus_tag="RH288_003089"
     CDS             967..1308
                     /gene="trbJ"
                     /locus_tag="RH288_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009424419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbJ"
                     /protein_id="HDV4032124.1"
                     /translation="MPPVLWRGWIPFCRCTEEKKVRNKQVVLLIAGISGIVTGIIVSL
                     NIPFIRQGLFYPASPVEIVVSLSLTFSVSVVFFVGAIVGWISVSEIYYSRMTGLNESS
                     EISEGTYNERK"
     gene            1262..1675
                     /gene="trbF"
                     /locus_tag="RH288_003090"
     CDS             1262..1675
                     /gene="trbF"
                     /locus_tag="RH288_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F-type conjugal transfer protein TrbF"
                     /protein_id="HDV4032125.1"
                     /translation="MNHRKYQRELIMRENKSNPELKIRSTERDYKYISRITGRYAGLS
                     LVFLTAGIVLWTVMDIIFDACIDSWKADPELNNSSYMWNILIYAIPYALYALAAGFLV
                     TFFSVPNVRINIRKYRDIPAEMSYAPGEHIKGGQE"
     gene            1675..3048
                     /locus_tag="RH288_003091"
     CDS             1675..3048
                     /locus_tag="RH288_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HDV4032126.1"
                     /translation="MPRIKPLLVLCAALLTVTPAASADVNSDMNQFFNKLGFASNTTQ
                     PGVWQGQAAGYAYGGSLYARTQVKNVQLISMTLPDINAGCGGIDAYLGSFSFINGEQL
                     QRFVKQIMSNAAGYFFDLALQTTVPEIKTAKDFVQKMASDINSMNLSSCQAAQGIIGG
                     LFPRTQVSQQKVCQDIAGESNIFADWAASRQGCTVGGKSDSVRDKASDKDKERVTKNI
                     NIMWNALSKNRMFDGNKELKEFVMTLTGSLVFGPNGEITPLSARTTDRSIIRAMMEGG
                     TAKIYHCNDSDKCLKVVADTPVTISRDNALKSQITKLLASIQNKAVSDTPLDDKEKGF
                     ISSTTIPVFKYLVDPQMLGVSNSMIYQLTDYIGYDILLQYIQELIQQARAMVATGNYD
                     EAVIGHINDNMNDATRQIAAFQSQVQVQQDALLVVDRQMSYMRQQLSARMLSRYQNNY
                     HFGGSTR"
     gene            3045..5867
                     /gene="traG"
                     /locus_tag="RH288_003092"
     CDS             3045..5867
                     /gene="traG"
                     /locus_tag="RH288_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating pair stabilization
                     protein TraG"
                     /protein_id="HDV4032127.1"
                     /translation="MNEVYVIAGGEWLRNNLNAIAAFMGTRTWDSIEKIALTLSVLAV
                     AVMWVQRHNVMDLLGWVAVFVLISLLVNVRTSVQIIDNSDLVKVHRVDNVPVGLAMPL
                     SLTTRIGHAMVASYEMVFTQPDSVTYSKTGMLFGAELVSKSTDFLSRNPEIANLFQDY
                     VQNCVMGDIYLNHKYTLEELMASADPYTLIFSRPSPLRGVYDSNNNFVTCKDASVSLK
                     DKLNLDTQSGGKTWHYYAQQLFGGRPDPNLLFSTLIGDSYSYFYGSSKSASQIIRQNV
                     TINALKEGITSYAARNGDSASLVNLATTSSMEKQRLAHVSIGHVAMRTLPMTQTILTG
                     IAIGIFPLLVLAAVFNKLTLSVLKGYVFALMWLQSWPLLYAILNSAMTFYAKQNGAPV
                     VLSEISQIQLKYSDLASTAGYLSMMIPPLSWMMVRGLGAGFSSVYSHFASSAISPTAS
                     AAGSVVDGNYSYGNMQTENVNGFSWSTNSTTSFGQMMYQTGSGATATQTRDGNMVMDA
                     SGAMSRLPVGINATRQIAVAQQEMAREASNRAESALHGFSSSIASAWNTLSQFGSNRG
                     SSDSVTSGADSTMSAQDSMMASRMRSAVESYAKAHNISNEQATQELASRSTRASAGMY
                     GDAHAEWGVKPKILGVGGGLGVRGGGRAGIDWSDDDAHQASSGSRASYDARHDIDAKA
                     SKDFKEASDYFTSRKVSESGSHTDNNADSRVDQLSAALNSAKQSYDQYTTNMTRSHEY
                     AEMASRTESMSGQMSEDLSQQFAQYVMKHAPQDAEAILTNTSSPEIAERRRAMAWSFV
                     QEQIQPGVDNAWRESRGDIGKGMESVPSGGGSQDIIADHQGHQAIIEQRTQDSNIRND
                     VKHQVDNMVTEYKGNIGDTQNSIRGEENIVRGQYSELQNHHKTEALSQNNKYNEEKSA
                     QERMPGADSPQELMKRAKEYQDKYKQ"
     gene            5883..6380
                     /locus_tag="RH288_003093"
     CDS             5883..6380
                     /locus_tag="RH288_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein"
                     /protein_id="HDV4032128.1"
                     /translation="MIMRCLAHIALVTVIQFIACYLADWGNAETVFMLFFIVLWQGLF
                     IWLFSQIRKKRDVSDEFKFSKGVWYITMPVSSLLSPLLSLMVFIIGTLYELRQVSGCI
                     SIKKWGQNQLKDQYDGSEKLDFGGIEQTPTIYYNPSTGYPMHGGFDSAGNTFGTRWQD
                     YYDRQ"
     gene            6412..7143
                     /locus_tag="RH288_003094"
     CDS             6412..7143
                     /locus_tag="RH288_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HDV4032129.1"
                     /translation="MKTKKLMMVTLVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIW
                     LEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKAD
                     KMDLRESQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVE
                     DVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNAN
                     KVNLKFEEAKPVLEDQLAKSIANIL"
     gene            7396..9549
                     /gene="traD"
                     /locus_tag="RH288_003095"
     CDS             7396..9549
                     /gene="traD"
                     /locus_tag="RH288_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001593043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HDV4032130.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIILYCLFIFFWILVGLV
                     LWVKISWQTFVNGCIYWWCTTLEGMRDLIRSQPVYEIQYYGKTFRMNAAQVLHDKYMI
                     WCGEQLWSAFVLASVVALVICLITFFVVSWILGRQGKQQSENEITGGRQLTDNPKEVA
                     RMLKKDGKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARQRGDMVVI
                     YDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDP
                     FWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIE
                     KTAISIRAVLTNYVKAIRYLQGIEHNGEPFTIRDWMRGVREDQKNGWLFISSNADTHA
                     SLKPVISMWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCY
                     VFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQ
                     YSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQTRP
                     KVAPEFIPRDINPEMENRLSAVLAAREAEGRQMASLFEPDVPEVVSGEDVTQAEQPQQ
                     PVSPAINDKKSDAGVNVPAGGIEQELKMKPEEEMEQQLPPGISESGEVVDMAVYEAWQ
                     REQNPDIQQKMQRREEVNINVHRERGEDVEPGDDF"
     gene            complement(9558..9956)
                     /gene="vapC"
                     /locus_tag="RH288_003096"
     CDS             complement(9558..9956)
                     /gene="vapC"
                     /locus_tag="RH288_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(fMet)-specific endonuclease VapC"
                     /protein_id="HDV4032131.1"
                     /translation="MLKFMLDTNICIFTIKNKPASVRERFNLNQGRMCISSVTLMELI
                     YGAEKSQMPERNLAVIEGFVSRIDVLDYDAAAATHSGQIRAELARQGRPVGPFDQMIA
                     GHARSRGLIIVTNNTREFERVDGLRIEDWS"
     gene            complement(9956..10183)
                     /gene="vapB"
                     /locus_tag="RH288_003097"
     CDS             complement(9956..10183)
                     /gene="vapB"
                     /locus_tag="RH288_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system antitoxin VapB"
                     /protein_id="HDV4032132.1"
                     /translation="METTVFFSNRSQAVRLPKAVALPENVKRVEVIAVGRTRIITPAG
                     ETWDEWFDGHNVSADFMDNREQPGMQERESF"
     gene            10265..15535
                     /gene="traI"
                     /locus_tag="RH288_003098"
     CDS             10265..15535
                     /gene="traI"
                     /locus_tag="RH288_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HDV4032133.1"
                     /translation="MMSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQ
                     GSVDKDVFTRLLEGKLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSVMAMLGGDKRL
                     IDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHA
                     VVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVV
                     GKHGMWEMPGVPVEAFSGRSQAIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAE
                     WMQTLKETGFDIRAYRDAADQRAETRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQF
                     TYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSV
                     RALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVA
                     ELVMMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLQEGMAFTPGNTVIVD
                     QGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQR
                     PATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVL
                     GRPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSNSLT
                     LRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASV
                     SEDAMTVVVPGRAEPASLPVSDSPFMALKLENGWVETPGHSVSDSAKVFASVTQMAMD
                     NATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETLLETAISLQ
                     KTGLHTPAQQAIHLALPVVESKNLAFSMVDLLTEAKSFAAEGTSFTELGGEINAQIKR
                     GDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMEKLTSG
                     QRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAV
                     GEMRSAGVDAQTLASFLHDTQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYALIA
                     AGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYSLINR
                     DVERALSGLESVKPSQVPRQEGAWVPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDI
                     PMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVP
                     VLNTANIRDGELRRLSTWETHRDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLIS
                     PREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRECGYVANSVWTVTAVSGDSVTLSDGQ
                     QTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKQMTGFESAYVAL
                     SRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKSDREVMNAERLFSTARELRDV
                     VAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGN
                     GLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDSGVVVRIAGE
                     GRPWNPRTITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEI
                     VRKMAENKPDLPDGKTEQAVRDIAGLERDRSAISEREAALPESVLREPQRVREAVREV
                     ARENLLQERLQQMERDMVRDLQKEKTLGGD"
     gene            15555..16301
                     /gene="traX"
                     /locus_tag="RH288_003099"
     CDS             15555..16301
                     /gene="traX"
                     /locus_tag="RH288_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="HDV4032134.1"
                     /translation="MTTDNTNTTRNDSLAARTDTWLQSLLVWSPGQRDIIKTVALVLM
                     VLDHANRILHLDQSWMFLVGRGAFPLFALVWGLNLSRHTHIRQEAINRLWGWAVIAQF
                     AYYLAGFPWYEGNILFAFAVAAQVLTWCETRTWWRSAETMLLLAMWLPFSGTSYGIAG
                     LLMLAVSHRLYRAEDRMERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSC
                     TGKSLPRFWYGDFFPTFYACHLTVLGVLAV"
     gene            16360..17220
                     /locus_tag="RH288_003100"
     CDS             16360..17220
                     /locus_tag="RH288_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV4032135.1"
                     /translation="MKITDHKLPEGIALTFRVPEGNIKHPLILLCHGFCGIRNVLLPS
                     FANAFTEAGFATITFDYRGFGESEGERGRLVPAMQTEDIISVINWAEKQVCIDNQRIG
                     LWGTSLGGCHVFNAAAQDKRVKSIVSQLAFADGEVLVTGEMNELEKASFLSTLNKMAE
                     KKKNTGKEMFVGVTRVLSDNESKVFFEKVKGQYPEMDIKIPFLTVMETLQYKPAESAA
                     KVQCPVLVVIAGQDSVNPPEQGRALYDAVASGTKELYEEADACHYDIYKGAFFERVAA
                     VQTQWFKKHL"
     gene            17323..17883
                     /locus_tag="RH288_003101"
     CDS             17323..17883
                     /locus_tag="RH288_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="HDV4032136.1"
                     /translation="MTEQKRPVLTLKRKTEGETPTRSRKTIINVTTPPKWKVKKQKLA
                     EKAAREAELAAKKAQARQALSIYLTLPSLDEAVNTLKPWWPGLFDGNTPRLLACGIRD
                     VLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEA
                     YAAGRLEKIRRQNRTKAELQAVLDGK"
     gene            18019..18231
                     /locus_tag="RH288_003102"
     CDS             18019..18231
                     /locus_tag="RH288_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANR family transcriptional regulator"
                     /protein_id="HDV4032137.1"
                     /translation="MNGFRNSSRNGQVWRYQRAGGRAVILEVSGRWMEAAEAWRRAAC
                     IAPRTDWQQFARKRAEHCHRRCRGRV"
     gene            18477..18551
                     /locus_tag="RH288_003103"
                     /pseudo
     CDS             18477..18551
                     /locus_tag="RH288_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
     gene            18912..>19054
                     /locus_tag="RH288_003104"
     CDS             18912..>19054
                     /locus_tag="RH288_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDV4032138.1"
                     /translation="MTKYALIGLLAVCATVLCFSLIFRERLCELNIHRGNTVVQVTLA
                     YEAR"
BASE COUNT         4672 a         4473 c         5557 g         4352 t
ORIGIN      
        1 agatagtcag ggaaggcatt gaccggtaat gaatgtgatg ctgcatatat cagcgcaata
       61 attgccgcat ttcccagtaa cgactctctt attatgtttc tgattatttc cagtttttct
      121 ttaaaagatc gcttttccat ttgtacctct gattaatatc acacaaacgc gaatattaca
      181 gacatgaata ctctcatgta aataataacc ggagtttaac atgataagta aacgcagatt
      241 ctctttaccc cggcttgata ttacgggaat gtgggtattt tccctgggtg tctggtttca
      301 tatcgtcgcc cgtcttgttt acagcaaacc ctggatggct ttttttctgg cggagctgat
      361 tgcggccatt ctcgtactgt tcggcgcata ccaggtgctg gatgcatgga ttgcccgtgt
      421 cagccgggaa gagcgtgagg cactggaagc caggcaacag gccatgatgg aagggcagca
      481 ggagggcgga catgtctctc actaaatcac tgctgttcac cctgttgctg agcgccgctg
      541 ctgtgcaggc ctccacccgg gatgaaatag agcgactctg gaatccgcag ggtatggcta
      601 cgcagcctgc acaaccggca gcaggcacgt cagccaggac agcaaagccg gctccccgct
      661 ggttccgcct cagtaatggc aggcaggtta acctggccga ctggaaggtg gtgctgttta
      721 tgcaggggca ttgcccttac tgtcaccagt ttgacccggt actgaaacag ctggcacagc
      781 agtacggctt ttccgttttt tcctacaccc tggatggtca gggggatacg gcctttcctg
      841 aagcattacc ggtgccaccg gaggtgatgc agaccttctt cccgaatatc ccggtggcca
      901 caccgaccac cttcctggtc aacgtcaaca cgcttgaggc attaccgctt ttacaggggg
      961 caacggatgc cgccggtttt atggcgcggg tggataccgt tttgcagatg tacggaggaa
     1021 aaaaaggtgc gaaataagca ggtggtgtta ctcattgccg gaatatccgg catcgtgacg
     1081 ggaataatcg tcagcctgaa tatccccttt atccgtcagg ggctttttta tcccgccagc
     1141 cctgtagaaa ttgtcgtttc gctgagtctt accttttctg tttctgttgt gttttttgtg
     1201 ggggcaattg tgggatggat ttcggtgtct gaaatatatt acagccgcat gaccggtctg
     1261 aatgaatcat cggaaatatc agagggaact tataatgaga gaaaataaaa gtaatcctga
     1321 gctcaaaatc agaagtacag aacgagatta taaatacatt tccagaatta ctggcaggta
     1381 tgctgggttg tctctggtat tcctgactgc cggaattgtt ttatggacag ttatggatat
     1441 tatttttgat gcctgtattg attcgtggaa agcggacccg gaattaaata attcgagtta
     1501 tatgtggaat atcctgatat atgccattcc gtatgcgtta tatgcgcttg cagccgggtt
     1561 tcttgttaca tttttttctg tccccaatgt acgaattaat atacggaaat atcgagatat
     1621 tcctgctgaa atgtcgtatg caccgggaga acacattaag ggagggcaag aatgatgcca
     1681 cgcattaaac ctcttctggt tctttgtgcc gccttactga cggtgacgcc tgcagcgtca
     1741 gcggatgtga acagcgacat gaatcagttc tttaataagc tgggatttgc ttccaatacc
     1801 acacagccgg gcgtctggca ggggcaggcc gccggctatg cttacggtgg ctccctgtat
     1861 gcccgtactc aggtcaaaaa tgttcagcta atttccatga cgctgccgga tatcaatgct
     1921 ggatgtggcg gcatcgacgc ctatctcggc tcgttcagtt ttattaatgg tgagcagttg
     1981 cagcgttttg ttaagcagat tatgagcaat gctgccggtt acttttttga ccttgccctg
     2041 cagacaacgg tgccggaaat aaaaaccgca aaagacttcg tgcagaaaat ggcaagcgac
     2101 attaacagta tgaacctcag ttcctgccag gctgcacagg ggattatcgg cgggcttttc
     2161 ccccggacgc aggtgtccca gcagaaagtc tgtcaggaca ttgccggtga gagcaatatt
     2221 tttgctgact gggcggcttc ccggcaggga tgtaccgttg gcgggaaatc tgacagtgtc
     2281 agggataaag ccagcgacaa ggataaggag cgggtgacca aaaacatcaa catcatgtgg
     2341 aatgcgcttt ccaaaaacag aatgtttgac ggcaacaaag agctgaaaga atttgtgatg
     2401 acgctgaccg gctcactggt gtttggtccc aacggcgaaa tcacaccgct gtcagccaga
     2461 accactgacc gctcaattat ccgggccatg atggaaggcg gcacagcaaa aatttatcac
     2521 tgcaacgatt ctgataaatg cctgaaagtg gtggcagaca caccggtgac tatcagccgg
     2581 gataatgcac tgaagtctca gattactaaa cttctggcca gcattcagaa caaggcggtc
     2641 agtgacacgc ctctggatga caaggaaaaa ggctttattt ccagtaccac catccccgtc
     2701 ttcaaatacc tggttgaccc gcagatgctc ggagtttcca acagcatgat ttaccagctg
     2761 acggactata tcggttacga catcctgctg cagtacattc aggagctgat acagcaggcc
     2821 cgggcgatgg tggccacggg aaattatgac gaagcggtta tcggacatat taacgacaac
     2881 atgaatgatg ccacccggca gattgcggcg tttcagtcac aggtgcaggt acagcaggat
     2941 gcgctgctgg ttgtcgatcg tcagatgagc tacatgcgtc agcagctttc cgcccgcatg
     3001 ctcagtcgtt accaaaacaa ctatcacttc ggagggagca cgcggtgaat gaagtttatg
     3061 tgattgccgg tggtgagtgg ttgcggaata acctgaacgc cattgccgcc tttatgggaa
     3121 ccaggacgtg ggattccatt gaaaaaattg cgctcacatt gtctgttctc gcggtggccg
     3181 taatgtgggt acagcggcac aacgtgatgg atttgctggg ctgggtggcc gtatttgtgc
     3241 ttatcagcct gctggttaat gtccgcacat cggtgcagat tattgataac agtgacctgg
     3301 tcaaagttca ccgggtggat aatgtgccgg tcggactggc gatgccactt tcactgacga
     3361 cccgtatcgg gcatgcaatg gtggccagtt acgagatggt cttcacgcaa ccggacagtg
     3421 tcacctacag caaaacgggg atgctgtttg gcgcagaact ggtatcaaaa agcaccgact
     3481 ttttgtcccg caatccggaa atcgccaatc ttttccagga ttatgtgcag aactgtgtta
     3541 tgggggatat ttacctgaac cacaaataca cgctggagga gctgatggcc tccgctgatc
     3601 cctacacgct gattttttcc cgccccagcc cgctgcgggg cgtttatgac agcaataata
     3661 atttcgtaac ctgtaaggac gcgtcggttt cgctgaaaga caagctgaat ctggacacac
     3721 agagtggcgg aaaaacctgg cattattatg cccagcagct atttggtgga cgccctgatc
     3781 ctaacctgct gttcagtacg ctgattggcg acagttacag ttacttctat ggctcaagta
     3841 aatcagccag ccagatcatc cgccagaatg tcaccatcaa tgcgctgaag gaggggatca
     3901 ccagttatgc cgcacgtaat ggtgattcgg ccagcctggt gaatctggcc accacgtcat
     3961 cgatggagaa acaacgtctg gcacatgtct ccatcggtca tgtggcgatg cggacactgc
     4021 ccatgacgca gaccatcctg acggggatcg ccatcggtat tttcccgctc ctggtactgg
     4081 cggctgtatt caacaaactg acgctgtctg tcctgaaagg ttatgtgttt gccctgatgt
     4141 ggctgcagtc atggccactc ttgtacgcca ttctgaacag tgccatgaca ttttatgcga
     4201 aacagaatgg tgcgccggtg gtgctctctg aaatttcaca gatacaactg aaatactccg
     4261 atctggcttc cactgccggg tatctttcca tgatgatccc gccattatcc tggatgatgg
     4321 tcagggggct tggggccgga ttttccagtg tgtacagcca tttcgcttcc tctgctatca
     4381 gcccgactgc cagtgcggca ggtagtgtgg ttgacggtaa ttactcctac ggcaacatgc
     4441 agacggaaaa cgtgaacggc ttcagctgga gcaccaacag caccacgtcg tttggtcaga
     4501 tgatgtacca gaccggcagt ggcgcaaccg ccacacagac ccgtgacggt aatatggtga
     4561 tggatgcaag cggagcgatg tcccgtttac cggtcggtat caatgcaacg cgtcagattg
     4621 cagtggcaca acaggaaatg gcccgggagg cgtcgaacag agcagaaagt gccctgcatg
     4681 gtttcagcag cagtattgcc agtgcctgga acacgctcag tcagtttggt tctaaccggg
     4741 ggagcagtga ctctgtcacc agtggtgctg acagtacgat gagtgcacag gactccatga
     4801 tggccagccg tatgcgcagt gcagtggaaa gctatgcgaa ggcgcataat atcagtaatg
     4861 agcaggcgac tcaggaactg gcatccagaa gtacgagagc ttctgccggg atgtatggag
     4921 atgctcatgc tgaatggggg gttaaaccta aaattcttgg tgttggtgga ggattaggcg
     4981 ttagaggtgg tggtcgggct ggcattgact ggagtgatga tgatgcgcat caggccagca
     5041 gtggttcacg ggccagctat gatgctcgtc atgatattga cgctaaagcc agtaaggact
     5101 ttaaagaggc cagcgattac tttaccagtc gcaaagtcag tgaatccggc agccatactg
     5161 acaataatgc tgattcccgg gtggatcaac tgtctgcagc cctgaattca gcgaaacaga
     5221 gttacgacca gtacacgacg aatatgaccc gcagccatga atatgctgaa atggcatccc
     5281 gtactgaaag catgagtggg cagatgagcg aagatttgtc gcaacagttt gcacagtatg
     5341 tgatgaaaca cgcaccgcag gatgccgaag ctattctgac aaataccagt tcgccggaga
     5401 ttgcagaacg ccgtcgggca atggcctggt cttttgtgca ggaacagata cagcctggtg
     5461 ttgataatgc ctggcgggaa tcccgtggcg atattggtaa aggaatggag agcgtacctt
     5521 cgggtggagg cagtcaggat attattgctg accatcaggg acatcaggcc attattgagc
     5581 aaagaacgca ggacagtaat atccgtaatg atgtaaaaca tcaggttgat aatatggtca
     5641 cagaatataa agggaatata ggtgatactc agaacagcat acgtggcgag gaaaatattg
     5701 taagaggaca gtattctgaa ctgcagaatc accataaaac agaggcatta tctcagaata
     5761 ataaatataa tgaagaaaag tcggctcagg aaagaatgcc cggggctgac agtccacagg
     5821 aactgatgaa aagggcaaag gagtatcagg ataagtataa gcaataatac tgtgtttggg
     5881 agatgataat gagatgttta gcccatattg ctctggtaac agtgatacag tttatcgcct
     5941 gttatctggc tgattggggg aatgccgaaa cagtttttat gctgttcttc atagtgctat
     6001 ggcagggact gtttatctgg ttgttctctc aaatacgaaa aaaacgggat gtgtcggatg
     6061 agtttaagtt tagtaaaggc gtttggtata taacgatgcc agtatcttcc ttactctctc
     6121 cgttattaag cctgatggtt tttatcattg gtacactata cgaattaagg caagttagtg
     6181 gttgcataag cataaaaaaa tgggggcaaa atcaactcaa agaccaatat gatgggagtg
     6241 aaaagttaga cttcgggggc attgaacaga ccccaacgat ctactataac ccttcaaccg
     6301 gatatcctat gcatggaggc tttgattcag cgggaaatac ttttgggact cgttggcagg
     6361 actattatga caggcaataa gaaaactgta gtttgtaaaa aaggtaattt gatgaaaaca
     6421 aaaaaattga tgatggttac actggtcagt tccactctgg ccctttcagg gtgtggtgcg
     6481 atgagcacag caatcaagaa gcgtaacctt gaggtgaaga ctcagatgag tgagaccatc
     6541 tggcttgaac ccgccagcga acgcacggta tttctgcaga tcaaaaacac gtctgataaa
     6601 gacatgagtg ggctgcaggg caaaattgct gatgctgtga aagcaaaagg gtatcaggtg
     6661 gtgacttctc cggataaagc ctactactgg attcaggcga atgtgctgaa ggccgataag
     6721 atggatctgc gggagtctca gggatggctg aaccgtggtt atgaaggcgc agcagttggt
     6781 gcagcgttag gtgccggtat caccggatat aattccaatt ctgccggtgc cacactcggt
     6841 gtgggccttg ctgccggtct ggtgggtatg gctgcagatg cgatggtgga agatgtgaac
     6901 tataccatga tcacggatgt gcagattgca gagcgtacta aggcaacggt gacaacggat
     6961 aatgttgccg ccctgcgtca gggcacatca ggtgcgaaaa ttcagaccag tactgaaaca
     7021 ggtaaccagc ataaatacca gacccgtgtg gtctcaaatg cgaacaaggt taacctgaaa
     7081 tttgaagagg cgaagcctgt tctcgaagac cagctggcca aatcaatcgc aaatattctc
     7141 tgattatctt ccggaggctg gtctgaccgg cctcctgact gacgcctcgc tttgctcgtt
     7201 gtccaacccc ggggagaaat aaaataaatt ttatttctcc ccggcgtttc cgaaataaat
     7261 atgaaaacac tgagcggttg tgcaaattct ttgtgcgacc gtgaagtgtt gccggcgaag
     7321 ccggaattta acggttatta atcttttcat cattaataat cagtccgact gactttcttt
     7381 cttcagaata tcatcatgag ttttaacgca aaggatatga cccagggcgg tcagattgcg
     7441 tccatgcgta tccgcatgtt cagtcagatc gccaatatca tactttactg cctgtttatt
     7501 tttttctgga tcctagttgg tctggtttta tgggtaaaaa taagctggca gacgtttgtg
     7561 aatggctgca tttactggtg gtgcaccacg ctggaaggca tgcgggattt aatcaggtcc
     7621 cagccggtct atgagatcca gtattacggc aaaaccttcc ggatgaacgc ggctcaggta
     7681 ctgcatgata aatatatgat ctggtgcggt gagcagttat ggtcggcatt cgttctggcg
     7741 tctgtcgtgg ccctggttat ctgcctgatc accttctttg ttgtctcctg gattctgggg
     7801 cgtcagggta aacaacagag cgaaaatgaa atcacaggtg gtcgtcagct gactgacaat
     7861 ccgaaagagg tggccaggat gctgaaaaaa gatggcaagg attccgatat ccggattggc
     7921 gatctgccga ttatccggga ttctgaaatc cagaacttct gtctgcacgg cactgtcggg
     7981 gccggtaagt cggaggttat ccgtcgtctg gccaactacg cccgtcagcg tggtgatatg
     8041 gtggtgattt atgaccgttc gggggaattt gttaaaagtt actatgatcc ctccatcgat
     8101 aaaatcctga atccgctgga tgcacgctgt gctgcctggg atttgtggaa ggagtgcctg
     8161 acacagccag attttgataa taccgcaaat actctgatcc cgatggggac aaaagaggac
     8221 ccgttctggc agggttcagg acgtaccatt tttgcggaag cggcatacct gatgcgtaat
     8281 gaccccaacc gcagctacag caaactggtg gacacactgc tttccatcaa aattgaaaag
     8341 ctgcgtacct tcctgcgtaa ttcaccggcg gccaacctgg tggaagagaa aatcgagaaa
     8401 acggccatat ccatccgtgc tgtgctgacc aactacgtga aagccatccg ttacctgcag
     8461 gggattgagc ataacggtga gcccttcacc atccgtgact ggatgcgtgg tgtccgggaa
     8521 gatcagaaaa acggctggct gtttatttcg tcgaacgccg acacccatgc ctccctgaag
     8581 ccggtgatct ccatgtggct gtccattgct attcgtggtc tgctggcaat gggagaaaac
     8641 cgtaaccgtc gtgtgtggtt tttctgtgac gagttaccca cgttacacaa actgccggac
     8701 ctggtggaga tcctgccgga agcccgtaag ttcggtggct gttatgtgtt tggtatccag
     8761 tcctatgccc agctggaaga tatctacggt gagaaagcgg ctgccacgct gtttgacgtc
     8821 atgaacaccc gtgccttttt ccgttctccc agccataaga ttgcagagtt cgctgccggt
     8881 gaaattggtg agaaagagca cctgaaagcc agcgagcagt attcctacgg tgctgatccg
     8941 gtacgtgacg gggtatcgac cggtaaggat atggagcgtc agacgctggt cagttattcc
     9001 gacattcagt ctctgccgga tctgacctgt tatgtcaccc tgcccggacc gtatccggca
     9061 gtaaaactct ccctgaaata tcagacacga ccgaaggtcg ctccggagtt tattccgcgt
     9121 gacatcaacc cggaaatgga gaaccgtctg agtgccgtac ttgccgcaag ggaagcagaa
     9181 ggtcgtcaga tggccagcct cttcgaaccg gatgtcccgg aggttgtttc cggagaagac
     9241 gtgactcagg ctgaacagcc gcaacagccg gtgtctcctg ccatcaacga taagaagtca
     9301 gatgcaggtg tgaatgttcc ggcagggggg atcgagcagg agctgaaaat gaaaccggaa
     9361 gaagagatgg aacagcaact gccacccggg atcagtgaat ccggtgaagt ggtggatatg
     9421 gccgtttatg aggcatggca acgggagcag aatccggata tccagcagaa gatgcagcgt
     9481 cgtgaagagg tgaacatcaa tgtgcaccgg gagcgcgggg aggatgttga gccgggagat
     9541 gatttctgat gaacaggtca gctccagtct tcaattctca gaccgtccac acgttcaaat
     9601 tcccgggtgt tattagtcac aataatcagt ccccgactgc gggcatgacc tgcgatcatt
     9661 tgatcaaatg gcccgacagg gcgtccctga cgggcaagtt ctgctcttat ctggccgctg
     9721 tgtgtggctg cggcagcgtc gtaatccaga acatcaatgc gggaaacaaa tccctcgatc
     9781 acagcgagat tacgttcagg catctggctt ttttctgcac catatatcag ctccatcagg
     9841 gtgaccgaac tgatacacat tctcccctgg ttcaggttaa aacgctccct gacgctggcg
     9901 ggtttgttct ttatcgtgaa aatgcagatg ttggtatcga gcataaactt cagcatcaga
     9961 atgactccct ttcctgcatg ccgggctgtt ccctgttatc cataaaatcg gcgctgacgt
    10021 tgtgtccgtc gaaccattcg tcccatgtct ctccggctgg cgtaatgatt ctggttcgtc
    10081 cgacagcaat cacttcaacg cgttttacgt tttccggcaa tgcaaccgct tttggcagtc
    10141 tgaccgcctg gctgcggttg ctgaaaaata cggtggtttc cattatttgc ctccttatgt
    10201 ggatatgtct tgtgtatatc cattgtggga ttgataccgg gatatgtcaa agggatatac
    10261 gtttatgatg agtatcgcgc aggtcagatc ggccggaagt gccggtaact attataccga
    10321 caaggataat tactatgtgc tgggcagcat gggagaacgc tgggccggca ggggggctga
    10381 acagctgggg ctgcagggca gcgtcgataa ggatgttttt acccgtcttc tggaggggaa
    10441 gctgccggac ggagcggatt taagccgcat gcaggatggc agtaataagc atcgtcccgg
    10501 ctacgacctg accttctccg cccccaaaag tgtctccgtg atggccatgt taggcggtga
    10561 taaacgtctt attgatgcac ataaccaggc cgtggatttt gctgtccgtc aggtggaggc
    10621 gctggcttcc acacgggtta tgacggacgg acagtcagaa acggtgctga ccggtaatct
    10681 ggtgatggca ctgtttaacc acgacaccag tcgcgatcag gaaccacagt tacacacaca
    10741 tgcggtagtg gccaatgtca cgcagcataa cggcgagtgg aagacattga gcagtgacaa
    10801 agtggggaaa acggggttca ttgagaatgt gtacgctaat cagattgcct tcggcaggct
    10861 ctaccgggaa aaactgaaag agcaggttga ggcgctgggc tatgaaacgg aagtggttgg
    10921 taagcacggt atgtgggaga tgccgggcgt accggtggag gccttctccg gacgctcaca
    10981 ggctatccgg gaggccgtcg gggaagacgc ctcgctgaaa tcccgggatg tggcggcact
    11041 ggatacgcga aaatccaaac agcacgtcga tcctgaagtc agaatggctg aatggatgca
    11101 gacgctgaag gaaaccgggt tcgacatccg ggcgtatcgt gacgcggcgg accaacgggc
    11161 ggagacccgc acgcagacgc ccggacccgc ttcacaggac gggccggatg tgcagcaggc
    11221 ggtgacacag gccattgccg gattaagtga acgcaaagtg cagtttacgt acacggacgt
    11281 gctggccaga acggtcggca tactgccgcc ggaaaatggt gtgattgaac gggcacgcgc
    11341 cggtatcgat gaggccatca gccgtgagca gcttatcccc ctcgatcgtg agaaggggct
    11401 gttcacgtcc gggattcatg tgctcgatga gctgtcagtc cgggcactca gtcgtgacat
    11461 catgaaacag aaccgggtga ccgtacatcc ggagaaaagt gtcccccgga cggccggtta
    11521 cagcgatgcg gtcagtgttc tggcacagga tcgcccgtcg ctggctattg tgtccgggca
    11581 gggcggtgca gccgggcagc gtgagcgggt ggcggagctg gtcatgatgg cccgggagca
    11641 ggggcgggag gtgcagatta tcgccgctga ccgtcgctcg cagatgaacc tgaagcagga
    11701 tgaacggctg tccggtgagc tgataaccgg acgtcgtcag ctgcaggagg gcatggcctt
    11761 cacgccgggc aatactgtta tcgttgacca gggcgaaaaa ctctccctga aagagacgtt
    11821 aaccctgctg gacggtgccg cacgtcataa cgtacaggtc ctgataaccg acagcgggca
    11881 gcgaaccggt acaggcagtg cactgatggc catgaaagat gccggggtga acacatatcg
    11941 ctggcagggg ggagaacagc ggccggccac catcatcagt gaaccggacc gtaatgtccg
    12001 ctatgcccgg ctggcaggag attttgctgc cagcgtgaaa gccggagaag agagcgtggc
    12061 acaggtcagc ggggtacggg aacaggccat actgacacag gccattcgca gtgagctgaa
    12121 aacacagggc gtgctcggac gcccggaggt aaccatgacc gccctgtcgc cggtctggct
    12181 ggacagccgg agccgttatc tgcgggatat gtaccgtccg gggatggtga tggagcagtg
    12241 gaacccggag acacgcagtc atgaccgcta tgttatcgac cgggtgacgg cgcagagtaa
    12301 cagcctgacc ctgcgggatg cgcagggtga aacgcaggtg gtgcgtattt cctccctgga
    12361 cagcagctgg tcgctgttcc ggccggaaaa aatgccggtg gcagacggcg agcgactgag
    12421 ggtgacaggg aaaattcccg gactccgcgt ctccggcggt gaccgcctgc aggtggcatc
    12481 cgtcagtgaa gatgcgatga cggttgttgt gccggggcgg gctgaaccgg cctccctgcc
    12541 tgtgagcgat tcaccattca tggcactgaa gctagagaac ggctgggtgg aaacgcccgg
    12601 gcattccgtc agcgacagtg cgaaggtttt tgcctccgtc acacagatgg caatggacaa
    12661 cgccaccctg aacggtctgg cccgcagcgg tcgtgatgtc cggctgtatt cctcactgga
    12721 tgaaacccgt actgcggaaa aacttgcccg ccatccctcc tttacggtgg tttctgagca
    12781 gataaaggcg cgtgccggtg agacattgct ggaaaccgct atcagtctgc agaaaaccgg
    12841 gcttcacacg ccggcacagc aggctattca tctggcgctt cctgtggtgg aaagtaaaaa
    12901 cctggccttc agcatggtgg acctgctgac agaggcgaag tcgtttgctg cagaaggaac
    12961 cagttttact gaactgggag gggaaatcaa tgcgcagata aaacgcggtg atttactgta
    13021 tgtggatgtg gcaaaaggct atggcacagg cctgctggtt tcccgtgcgt cgtatgaggc
    13081 agaaaagagc attcttcgcc atattctcga aggtaaggag gcggtcacgc cactgatgga
    13141 gagagtacct ggcgaactca tggagaaact gacatcagga cagcgtgccg ctacccgcat
    13201 gatactggaa acgtccgacc gtttcacggt ggtgcagggc tatgccggtg tgggtaagac
    13261 cacacagttc cgggcggtga tgtcagccgt gaacatgctg ccggagagtg aacgtccccg
    13321 tgtcgtgggg ctggggccca cgcaccgtgc ggtcggtgag atgcgcagcg ccggcgtgga
    13381 tgcacagacg ctggcgtcct ttctgcatga cacgcagctg ctgcagcgca gcggagaaac
    13441 gccgaatttc agcaacacgc tgttcctgct cgatgagagc tctatggtgg gcaataccga
    13501 catggcacgg gcatacgccc tgattgcggc cggtggcggt cgtgccgtgg ccagtggtga
    13561 cacggaccag ttgcaggcca tcgcgcccgg tcagcctttc cgtctccagc agacgcgcag
    13621 tgctgccgat gtggccatca tgaaggagat tgtgcgccag acgccggagc tgcgggaggc
    13681 ggtatacagc ctgattaacc gggatgtgga aagggcactg tccgggcttg agagcgtgaa
    13741 accgtctcag gtgccacgtc aggagggcgc atgggtaccg gagcactccg tgacggagtt
    13801 cagtcacagc caggaagcga aactggcaga agcgcagcag aaggcgatgc tgaaaggtga
    13861 ggcttttccg gatattccca tgacactgta tgaagccatt gtccgcgatt ataccggcag
    13921 gacgccggaa gcacgggagc agacgctgat tgtcacgcat ctgaatgagg accggcgcgt
    13981 actgaacagc atgattcatg atgcacggga aaaggccggt gagctgggaa aagagcaggt
    14041 catggtgcct gtcctgaaca cagcgaatat acgcgacggg gagttgcgtc gtctctccac
    14101 ctgggagaca catcgggacg cacttgccct ggtggataat gtgtatcacc ggattgccgg
    14161 tatcagcaag gatgacgggc tgataaccct gcaggatgcg gaaggtaaca cgcggctgat
    14221 ttcgccccgg gaggcggtgg ctgaaggcgt cacactgtac actccggaca ccatccgggt
    14281 gggaaccggt gaccggatgc gcttcacgaa gagtgaccgg gagtgcggtt atgtggccaa
    14341 cagcgtctgg acggtgacag cggtttccgg tgacagtgtc acgctgtcgg acggacagca
    14401 gacccgggtg attcgccccg gtcaggagcg ggcagagcaa catattgacc tggcctatgc
    14461 catcaccgcc cacggtgcgc agggggcaag tgaaaccttt gccattgcgc ttgaaggcac
    14521 ggaaggtaac cggaaacaga tgaccggctt tgagtcagcc tacgtggccc tgtcgcgtat
    14581 gaagcagcat gtgcaggtgt ataccgataa ccgtcagggc tggacggatg ccattaacaa
    14641 tgccgtacag aaaggaactg cccacgatgt gctagagccg aaatcggacc gggaggtcat
    14701 gaatgcagag cggctgttca gtacggcgcg ggagctgcgg gacgtggtgg ccggccgtgc
    14761 cgttctccgt caggcagggc tggccggggg agacagtcct gcacggttta ttgcacccgg
    14821 gcgcaaatat ccgcagccgt atgtggcact gccggctttt gaccgtaacg gcaagtcagc
    14881 tggtatctgg ctgaacccgc tgaccacgga tgacggaaac gggctgcggg gcttcagtgg
    14941 tgaaggccgg gtgaaaggca gcggggatgc gcagttcgtg gccctgcagg gcagccgtaa
    15001 cggagagagc ctgctggctg ataatatgca ggatggtgtc cggattgccc gtgataatcc
    15061 tgacagcggt gtggtggtaa gaatcgccgg tgaaggtcgt ccgtggaatc ccagaaccat
    15121 caccggtggt cgcgtgtggg gggatatccc ggacaacagc gttcagccgg gagccggaaa
    15181 tggcgaaccg gtcacggcag aggtactggc acagcggcag gctgaagagg ccatccgccg
    15241 tgaaacggaa cgccgtgcgg atgaaattgt ccgtaaaatg gcagagaaca aacctgacct
    15301 gccggacggc aaaacagagc aggctgtcag ggatattgcc gggctggagc gtgaccggtc
    15361 tgccatatct gaacgggaag ccgcgctgcc ggagagtgta ctgcgtgaac cacaacgggt
    15421 gcgggaagcg gtccgggagg ttgcccggga aaatctgctg caggagcgac tgcagcagat
    15481 ggagcgggat atggttcgtg acctgcagaa agagaaaacc ctgggcggag actgacacag
    15541 gaagataaac gctgatgaca acggataaca cgaacacaac acgtaatgat tcactggctg
    15601 cccggaccga tacctggttg cagtcgttgc tggtctggtc acccggacag cgggatatca
    15661 tcaaaacggt ggcactggtg ctgatggttc tggaccatgc aaaccgcatt ctgcatctgg
    15721 accagtcgtg gatgtttctg gtcgggcgtg gggcctttcc gctgtttgcc ctggtgtggg
    15781 ggctgaatct gtcccgtcat acgcatatcc ggcaggaggc cattaaccgg ctgtggggat
    15841 gggcggtgat tgcccagttc gcatattatc tggccggctt tccctggtat gaggggaata
    15901 tcctgtttgc ctttgcagtt gcggcacagg tgctgacatg gtgtgaaacg cgcacctggt
    15961 ggcgttccgc agagaccatg ttgcttctgg caatgtggtt gcctttctcc ggcaccagtt
    16021 acggcattgc cgggctgctg atgctggcag tcagccacag gctgtaccgg gcggaagaca
    16081 gaatggaacg tctggcgctg gtcgcctgcc tgctggctgt tattccggcg cttaaccttg
    16141 ccaccagtga tgcagcggcg gtggccggcc ttgtgatgac ggtgctgact gttggtctgg
    16201 tgtcctgtac agggaaatca ctaccccgtt tctggtacgg ggattttttc ccgacgttct
    16261 atgcctgtca tcttactgtg ctgggcgttc tggctgtgtg actggtatga tgctggcgct
    16321 gattctgctt attaataaac aacataacac aggatattta tgaaaattac ggatcacaaa
    16381 ctccctgaag gtattgccct gacatttcgt gtcccggaag gaaatataaa acatcctttg
    16441 attctcttat gccatggatt ttgcggtatc cggaatgttc tgctgccttc ctttgcgaat
    16501 gcgtttacag aagccgggtt tgcaacgatt acttttgatt atcgtggatt cggtgagagt
    16561 gaaggggaac gaggtcgtct ggttccggca atgcagaccg aagatattat ttcagttatc
    16621 aattgggcag aaaagcaggt atgtattgat aatcagcgta taggattatg gggaacatcg
    16681 ctgggtgggt gtcatgtatt caatgcagct gcgcaggata aaagagtgaa aagtattgtc
    16741 agccagctgg cttttgctga cggtgaggtt ctggttaccg gagaaatgaa tgaactggag
    16801 aaagcttctt ttctgtccac gctgaataaa atggcagaaa agaagaaaaa taccgggaaa
    16861 gagatgtttg tgggggttac ccgggtactg agtgataatg aatcaaaggt attcttcgag
    16921 aaggtaaaag gtcagtatcc tgaaatggat ataaaaatac ctttccttac ggttatggag
    16981 acgttgcaat ataaaccggc agagagcgca gccaaagtac agtgcccagt tttggttgtt
    17041 attgccggcc aggatagtgt taatccacca gaacagggaa gagccttata tgatgctgtt
    17101 gcttctggta ctaaggaatt atacgaggaa gctgacgcat gccattatga tatttataaa
    17161 ggcgcgtttt ttgaacgtgt ggcggcagta cagacgcaat ggtttaaaaa acatctttaa
    17221 ttgtcggtat taatatgtca gaggtcgttg aggtcagctt aatatcatag tgagtagttt
    17281 caacgacctg gaggacatat tttcacaaag gtcagggcaa tcatgacaga gcagaaacga
    17341 ccggtactga cactgaaacg gaaaacggaa ggggaaacac cgacccggag ccggaaaacc
    17401 atcatcaatg tcaccacgcc accaaaatgg aaggtgaaaa agcagaaact ggcggagaag
    17461 gctgcccggg aagcagagct ggcggcgaag aaagcacagg ccagacaggc gctgtccatt
    17521 tatctgacgc tgccctcgct ggatgaggcg gtgaacactc tgaaaccttg gtggccggga
    17581 ttgtttgacg gtaacacgcc ccggcttctg gcctgcggta tccgggacgt gttactggaa
    17641 gacgtggcgc agcggaatat cccgctctcg cataaaaaac tgcgccgggc gctgaaggcc
    17701 atcacccgtt cagaaagcta tctgtgtgcc atgaaagccg gtgcctgccg gtatgacacg
    17761 gaagggtatg tgacggagca tatttctcag gaggaggaag cgtatgcggc agggcgtttg
    17821 gagaaaattc gccgccagaa ccggacaaag gcagaacttc aggccgtgct tgatgggaaa
    17881 taaaaaaagc ctccccggaa accggggagg ctgaaacaat aaggcttaaa aggaaataac
    17941 ttccgtaccc gaaaggaagc cagtccactg aattatttac cacaataata ctgacgacta
    18001 aaagggagga gcagaaaaat gaatggattc agaaacagtt cacggaacgg tcaggtctgg
    18061 cgttaccagc gtgccggcgg gcgggccgtt attctggagg tcagtggacg ctggatggaa
    18121 gcggcagaag catggcgacg ggctgcctgc atagctcccc ggacagactg gcaacagttt
    18181 gcccggaaaa gggctgaaca ctgccaccgg cgctgccggg gaagggtgta acgaaaaaag
    18241 cagccttcat tactccagga gtcagaaggc tgaaaggagt ttatgagatt tgcttttttt
    18301 aatatccggt cgggcagtat gaccggccag ttctgagtag cacagagttt tttccgtatt
    18361 aagtcgcgat tttatatttt gtgattaatt tcacaaaata aggtcttatt caatgtgtgc
    18421 tgcgatattc aggggggctg aaatacaggt gccatttatc tgatatggag aataacatga
    18481 ggaaatatat tccactggta ttatttatct tttcatggcc ggtattgtct gcagatgttc
    18541 acgggcagat ttatgcacca gacagaatga atgttaatta gtttatgaat acaacagggg
    18601 ctgatcagca atcaccggaa catcgtagct gacgcgttcg caatgctcag ttgtcccccc
    18661 cggaaacggg aaaaagtaag ttttcccccg ctcccggcgt ttttgtaaca aaaacaggca
    18721 aatgggggta atagtcagca acagggaatg tggtattatc gcggcgggtg tttgagcctt
    18781 tctggttcag gcaagacgca ggtaccagaa atgcgaagac cccactcgtt aatccattaa
    18841 ctcgtgaggt ctgcatgaag taccttaaca ctactgattg tagcctcttc tttgctgaga
    18901 ggtcaaagtt tatgacgaaa tatgccctta tcgggttgct cgccgtgtgc gccacggtgt
    18961 tgtgtttttc actgatattc agggaacggt tatgtgagct gaatattcac agaggaaata
    19021 cagtggtgca ggtaactctg gcctacgaag cacg
//
LOCUS       DAPHKZ010000085        18944 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.085, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000085 DAPHKZ010000000
VERSION     DAPHKZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18944
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.085"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            6..557
                     /locus_tag="RH288_003105"
     CDS             6..557
                     /locus_tag="RH288_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein"
                     /protein_id="HDV4032139.1"
                     /translation="MSAFKKSLLVAGVAMILSNNVFADEGHGIVKFKGEVISAPCSIK
                     PGDEDLTVNLGEVADTVLKSDQKSLAEPFTIHLQDCMLSQGGTTYSKAKVTFTTANTM
                     TGQSDLLKNTKETEIGGATGVGVRILDSQSGEVTLGTPVVITFNNTNSYQELNFKARM
                     ESPSKDATPGNVYAQADYKIAYE"
     gene            617..3121
                     /locus_tag="RH288_003106"
     CDS             617..3121
                     /locus_tag="RH288_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV4032140.1"
                     /translation="MYKKLKLTTISELIKNIYCSLSVIIIGCASAYAVEFNKDLIEAE
                     DRENVNLSQFETDGQLPVGKYSLSTLINNKRTPIHLDLQWVLIDNQTAVCVTPEQLTL
                     LGFTDEFIEKTQQNLIDGCYPIEKEKQITTYLDKGKMQLSISAPQAWLKYKDANWTPP
                     ELWNHGIAGAFLDYNLYASHYAPHQGDNSQNISSYGQAGVNLGAWRLRTDYQYDQSFN
                     NGKSQATNLDFPRIYLFRPIPAMNAKLTIGQYDTESSIFDSFHFSGISLKSDENMLPP
                     DLRGYAPQITGVAQTNAKVTVSQNNRIIYQENVPPGPFAITNLFNTLQGQLDVKVEEE
                     DGRVTQWQVASNSIPYLTRKGQIRYTTAMGKPTSVGGDSLQQPFFWTGEFSWGWLNNV
                     SLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDVTRSDAQLHNQDKETGYSYRANYSK
                     RFESTGSQLTFAGYRFSDKNFVTMNEYINDTNHYTNYQNEKESYIVTFNQYLESLRLN
                     TYVSLARNTYWDASSNVNYSLSLSRDFDIGPLKNVSTSLTFSRINWEEDNQDQLYLNI
                     SIPWGTSRTLSYGMQRNQDNEISHTASWYDSSDRNNSWSVSASGDNDEFKDMKASLRA
                     SYQHNTENGRLYLSGTSQRDSYYSLNASWNGSFTATRHGAAFHDYSGSADSRFMIDAD
                     DTEDIPLNNKRAVTNRYGIGVIPSVSSYITTSLSVDTRNLPENVDIENSVITTTLTEG
                     AIGYAKLDTRKGYQIIGVIRLADGSHPPLGISVKDETSHKELGLVADGGFVYLNGIQD
                     DNKLALRWGDKSCFIQPPNSSNLTTGTAILPCISQN"
     gene            3137..3886
                     /locus_tag="RH288_003107"
     CDS             3137..3886
                     /locus_tag="RH288_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV4032141.1"
                     /translation="MRYLNTKNIIAAGVLLSCMSSIAWGAIIPDRTRIIMNESDKGEA
                     LKLTNQSKNLPYLAQTWIEDTKGNKSRDFIVTVPPMVRLNPSEQIQIRMITQEKIAQL
                     PKDRETLFYFNVREIPPKTDKKNVMQVTMQHALKLFWRPKAIELEDDGVMTYEKVEII
                     RRNDGSIRFNNKMPYHVTLGYIGTNGVTMLPQTQSLMVTPFSYANTQFKNVPSTFQVG
                     YINDFGGLSFYEINCPVVNNICNISVANRDQ"
     gene            3888..4952
                     /locus_tag="RH288_003108"
     CDS             3888..4952
                     /locus_tag="RH288_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4032142.1"
                     /translation="MRYLLIVITFFMGFSSLPAWAMDCYAEHEGGNTVVIGYVPRISI
                     PSDGKKGDKIWQSSEYFMNVFCNNALPGPSPGEEYPSAWANIMMLLASGQDFYNQNSY
                     TFGVIYNGVDYDSTSPLPIAAPVCIDIKGAGTFGNGYKKPAVCSGGPEPQLSATFPVR
                     VQLYIKLAKNANKVNKKLVLPDEYIALEFKGMSGAGAIEVDKNLTFRIRGLNNIHVLD
                     CFVNVDLEPADGVVDFGKINSRTIKNTSVSETFSVVMTKDPGAACTEQFNILGSFFTT
                     DILSDYSHLDIGNGLLLKIFHNDGTATEFNRFSQFASFSSSSAPSVTAPFRAELSANP
                     AETVVEGPFSKDVILKITYN"
     gene            complement(4995..5195)
                     /gene="glgS"
                     /locus_tag="RH288_003109"
     CDS             complement(4995..5195)
                     /gene="glgS"
                     /locus_tag="RH288_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HDV4032143.1"
                     /translation="MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTW
                     FCARYAWYCQQMMQARELELEH"
     gene            5464..6093
                     /locus_tag="RH288_003110"
     CDS             5464..6093
                     /locus_tag="RH288_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HDV4032144.1"
                     /translation="MILFADYNTPYLFAISFVLLIGLLEIFALICGHMLSGALDAHLD
                     HYDSITTGHISQALHYLNIGRLPTLVVLCLLAGFFGLIGILLQHACIMVWQSPLSNLF
                     VVPVSLLFTIIAVHYTGKIVAPWIPRDHSSAITEEEYIGSMALITGHQATSGNPCEGK
                     LTDQFGQIHYLLLEPEEGKIFTKGDKVLIICRLSATRYLAENNPWPQIL"
     gene            6120..7781
                     /locus_tag="RH288_003111"
     CDS             6120..7781
                     /locus_tag="RH288_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDV4032145.1"
                     /translation="MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVR
                     TGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNARIAAFEA
                     ERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGGAAGDANTGNVGGGNLAEQAL
                     SAALSYRTQAPLIDSLLNEIGVSGGSLAALTSPLTSTTPVEEKAE"
     gene            8022..8081
                     /locus_tag="RH288_003112"
     CDS             8022..8081
                     /locus_tag="RH288_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDV4032146.1"
                     /translation="MMKLVIILIVLLLVSFAAY"
     gene            8397..8456
                     /gene="ibsE"
                     /locus_tag="RH288_003113"
     CDS             8397..8456
                     /gene="ibsE"
                     /locus_tag="RH288_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsE"
                     /protein_id="HDV4032147.1"
                     /translation="MMKFVIILVVLLLLSFPTY"
     gene            complement(8576..10009)
                     /gene="hldE"
                     /locus_tag="RH288_003114"
     CDS             complement(8576..10009)
                     /gene="hldE"
                     /locus_tag="RH288_003114"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HDV4032148.1"
                     /translation="MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVN
                     TIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
                     QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMK
                     LIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAA
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNP
                     LEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANG
                     GEVLVLNFEDGCSTTNIIKKIQQDKKG"
     gene            complement(10057..12897)
                     /gene="glnE"
                     /locus_tag="RH288_003115"
     CDS             complement(10057..12897)
                     /gene="glnE"
                     /locus_tag="RH288_003115"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HDV4032149.1"
                     /translation="MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQD
                     SVIAHPEWLTELESQPPQADEWQHYAAWLQEALCNVSDEAGLMRELRLFRRRIMVRIA
                     WAQTLALVTEESILQQLSYLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGF
                     VYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELR
                     AMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLSAIAELHLLSENDAEQLRVAYLFLRRLENLLQSINDEQT
                     QTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSE
                     QWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLM
                     PHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIA
                     SQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQ
                     LLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRG
                     FAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFS
                     TRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQ
                     LTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIE
                     FITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHL
                     ALQELPGHVSEDCFTAERELVRASWQKWLVEE"
     gene            complement(12920..14221)
                     /gene="ygiF"
                     /locus_tag="RH288_003116"
     CDS             complement(12920..14221)
                     /gene="ygiF"
                     /locus_tag="RH288_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HDV4032150.1"
                     /translation="MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETP
                     DNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEV
                     WPNGELPADLASRVQPLFSTDFYREKWLVAVDGSQIEIALDQGEVKAGEFAEPICELE
                     LELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAK
                     ADVEQGLEAALELALAQWQYHEELWVRGNDAAKEQVLAAISLVRHTLMLFGGIVPRKA
                     STHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKI
                     SDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQ
                     AWLENWQGLHHAIATGQRIEIEHFRNEANNQEPFWLHSGKR"
     gene            14463..15083
                     /locus_tag="RH288_003117"
     CDS             14463..15083
                     /locus_tag="RH288_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDV4032151.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHY
                     RLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWIPLKQLSTEPSLRSRVPDLENQV
                     KTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVDAASV
                     QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPSRKRKDRWMN"
     gene            15147..16385
                     /gene="cca"
                     /locus_tag="RH288_003118"
     CDS             15147..16385
                     /gene="cca"
                     /locus_tag="RH288_003118"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /protein_id="HDV4032152.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDD
                     NGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLALM
                     REMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPA
                     PAKWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPA
                     GVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQR
                     VEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREEL
                     TRRRIAAVASWKEQRCPKPE"
     gene            complement(16566..17387)
                     /gene="bacA"
                     /locus_tag="RH288_003119"
     CDS             complement(16566..17387)
                     /gene="bacA"
                     /locus_tag="RH288_003119"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDV4032153.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPA
                     VVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGF
                     LTNGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF"
     gene            complement(17478..17846)
                     /gene="folB"
                     /locus_tag="RH288_003120"
     CDS             complement(17478..17846)
                     /gene="folB"
                     /locus_tag="RH288_003120"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HDV4032154.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKS
                     DDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAV
                     ARAANVGVIIERGNNLKENN"
     gene            17951..18568
                     /gene="plsY"
                     /locus_tag="RH288_003121"
     CDS             17951..18568
                     /gene="plsY"
                     /locus_tag="RH288_003121"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDV4032155.1"
                     /translation="MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGAT
                     NVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE"
     gene            complement(18581..>18944)
                     /gene="ttdR"
                     /locus_tag="RH288_003122"
                     /gene_synonym="dan"
     CDS             complement(18581..>18944)
                     /gene="ttdR"
                     /locus_tag="RH288_003122"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TtdR"
                     /protein_id="HDV4032156.1"
                     /translation="HDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQW
                     ALEGKGIMLRSEWDVLPFLESGKLVRVLPEYAQSANIWAVYREPLYRSMKLRVCVEFL
                     AAWCQQRLGKPDEGYQVM"
BASE COUNT         4944 a         4906 c         4458 g         4636 t
ORIGIN      
        1 atattatgtc cgcttttaaa aagtcacttc ttgttgctgg cgtagcaatg attctttcca
       61 ataacgtgtt tgctgatgaa ggtcacggta ttgttaaatt taaaggtgaa gttatctctg
      121 ctccatgttc tattaaacca ggtgacgaag atttaactgt aaatctgggt gaagtagcag
      181 ataccgtact gaaaagcgat cagaaatctt tggctgaacc tttcactatt cacctgcagg
      241 actgcatgct gagtcagggt ggaactactt attcaaaagc gaaggttact ttcactacag
      301 caaataccat gacgggtcag tctgatcttc tgaaaaatac caaagaaact gaaatcggcg
      361 gcgccactgg cgttggcgta cgtattctgg acagccagag cggcgaagta actttaggta
      421 ctccggtagt aattacgttc aacaatacca acagctatca ggaactgaat ttcaaagctc
      481 gtatggaatc cccaagcaaa gatgccaccc cgggcaacgt ttacgctcag gctgactaca
      541 agattgctta cgagtaatcg catttggccg ggttcgcccg gccacatcat taacggatta
      601 atgataagtg gatcagatgt ataaaaaatt aaaattaacc acaataagcg aattgattaa
      661 aaatatttat tgttcattat ccgttatcat cattggttgt gcgtcagctt atgccgttga
      721 attcaacaaa gatttaatcg aagccgaaga tcgtgaaaac gttaaccttt cccaatttga
      781 aactgatggc caattacccg tcggcaaata ttcactaagc actctgatta ataataagag
      841 gacgccaatc caccttgacc tccaatgggt attaattgat aaccaaactg cagtttgcgt
      901 gacaccagag caattaacat tattaggatt tactgatgaa tttattgaaa aaactcagca
      961 aaacctgatc gatggttgtt accctatcga aaaagaaaaa caaattacaa cttatctcga
     1021 taaagggaaa atgcaattat ccatatctgc acctcaggca tggttaaaat acaaagatgc
     1081 aaactggacg cctcctgaac tttggaatca tggtattgct ggggcatttc ttgactacaa
     1141 tttatatgcc tctcattatg caccacatca gggcgataat tcgcaaaata taagttccta
     1201 tgggcaggct ggggttaatc ttggggcctg gcgcctgcgt actgattacc agtacgatca
     1261 gtcatttaac aatggcaaaa gccaggcgac caacctggat tttccgcgta tttatttgtt
     1321 tcgcccaatc ccagcaatga atgcaaaact aactataggt caatacgata ctgaatcctc
     1381 tattttcgac tctttccatt tttctggcat ttcgttgaaa agcgatgaga atatgttacc
     1441 gccagaccta cgtggttacg caccgcaaat cacgggtgtc gcacaaacga atgcaaaggt
     1501 cactgtctca cagaacaacc gtattattta tcaagaaaat gttcctccag gcccatttgc
     1561 tattaccaat ttattcaata cattacaggg gcaacttgac gtcaaggttg aagaagagga
     1621 cggacgcgtt acgcaatggc aagttgcatc taatagtatt ccttatctga cgcgtaaagg
     1681 gcagattcgc tacaccactg ctatgggtaa accgaccagc gttggtggtg attccttaca
     1741 acaacccttc ttctggactg gtgaattctc atggggttgg ctgaacaatg tatccctgta
     1801 tggtggttca gttttaacaa accgtgatta tcaatctctg gctgccggcg ttggttttaa
     1861 ccttaactca ttaggttcat tatcttttga tgtcacacga tctgatgctc agttgcataa
     1921 tcaggataaa gaaacgggtt atagctaccg cgctaactat tcaaaacgtt ttgaatctac
     1981 cggtagccag ctcactttcg ctggttaccg tttctctgat aaaaactttg tgacaatgaa
     2041 tgaatatatc aatgacacta accattacac gaattatcag aatgaaaaag agagttatat
     2101 tgtcacgttt aaccagtatc ttgaatcatt aaggttaaat acatacgtaa gtttggctcg
     2161 taatacttac tgggacgcca gcagtaatgt gaattattca ttatcactta gccgcgattt
     2221 tgatatcggg ccattaaaaa acgtctccac ttctctaaca tttagccgaa taaactggga
     2281 agaagacaac caggatcaac tgtacctaaa tatttcgatt ccctggggaa ctagtagaac
     2341 attgagctat ggtatgcaac gaaatcagga taatgagatt tcgcatactg cttcgtggta
     2401 tgactcttcc gatcgaaata attcctggag cgtttctgct tcaggcgaca atgatgaatt
     2461 caaagatatg aaagcgtcac tacgcgccag ttatcagcat aataccgaga acggtcgact
     2521 ctacctctcc ggtacatcac agcgagacag ttattattct ctgaatgcca gttggaatgg
     2581 ttcattcact gcgactcgcc acggtgccgc tttccacgac tatagcggta gtgctgactc
     2641 gcgttttatg atcgacgcag acgacactga agatattccg ttgaacaata aacgcgcggt
     2701 aactaatcgg tatggcatcg gagttattcc atcagtcagc agttacataa caacatcatt
     2761 aagtgttgat acccgaaatc tgccagaaaa tgtggatatc gaaaactcgg ttatcaccac
     2821 caccttaacc gagggtgcta ttggctacgc caaacttgat acccgcaagg gctaccaaat
     2881 cataggggtt attcgcctgg cagatggtag tcatccacca ctggggatta gcgtaaaaga
     2941 tgaaaccagc cacaaagaat taggactggt tgctgatggc ggctttgtat acctcaacgg
     3001 cattcaggat gataacaaac ttgctttacg ctggggtgac aaatcttgtt ttattcaacc
     3061 acccaatagc agcaacttaa ccaccggaac ggctatttta ccgtgtatta gccaaaatta
     3121 attcaggatg aaactaatgc gctacttaaa tacaaagaat atcattgcag caggagtatt
     3181 actctcctgt atgagcagca ttgcctgggg tgccatcatc ccggatcgta cccgtatcat
     3241 aatgaatgag tcagataaag gcgaagcatt aaaacttact aatcaaagta aaaacctgcc
     3301 ctatctggcc caaacatgga tagaagatac gaaaggcaat aaatcgcgtg actttattgt
     3361 cactgttcct ccaatggtgc gtttaaatcc cagtgagcaa attcaaataa gaatgataac
     3421 tcaggaaaaa attgctcaac ttcctaaaga cagagaaacg ctcttctatt ttaacgtgcg
     3481 agaaataccg cccaaaacag ataaaaaaaa tgtgatgcaa gtcactatgc agcacgcatt
     3541 gaaactattc tggcggccaa aagccattga attagaagac gatggggtaa tgacttacga
     3601 aaaagttgaa atcattcgta gaaatgacgg ttcgatccgc tttaacaata agatgcctta
     3661 tcacgttacg ctgggttata tcggaacaaa tggggtaacg atgttaccac aaacgcaaag
     3721 cttaatggta acccctttta gctatgcaaa tacgcagttt aaaaatgttc cgtcaacttt
     3781 tcaggtgggt tatatcaatg actttggtgg attaagtttt tatgaaataa actgccctgt
     3841 agtaaataac atttgtaata tttctgtagc caaccgagat caataatatg cgctacttgt
     3901 taattgttat tacttttttt atgggtttta gttcattacc tgcatgggca atggactgct
     3961 atgctgaaca tgaaggtgga aataccgttg tcattggtta cgtaccaaga atctctatcc
     4021 ccagcgatgg taaaaaaggt gataaaatct ggcaaagcag tgaatatttt atgaatgttt
     4081 tctgtaataa tgcactacca ggcccatctc caggagaaga atacccatct gcatgggcaa
     4141 atataatgat gttgttagca tcaggtcaag acttttataa tcaaaactct tatactttcg
     4201 gtgtaattta taatggggtt gattatgatt ctacatctcc actacctatt gcagcacctg
     4261 tatgtattga tataaaagga gccggaacct tcgggaatgg ctacaaaaag cccgcagtct
     4321 gtagtggcgg tcctgaaccg caattatcag caacttttcc agtacgagtg cagctatata
     4381 ttaagctagc taaaaatgcc aataaagtaa ataaaaaact tgtattacct gacgaatata
     4441 tagcacttga atttaaaggt atgagcggag caggtgctat agaagtagat aaaaatctga
     4501 ccttcaggat tcgcggatta aataacattc atgtccttga ctgctttgtt aatgttgatc
     4561 tggaaccagc tgatggcgtt gtcgactttg gtaaaataaa ttcccgaaca attaaaaata
     4621 ccagcgtgag tgagacgttt agcgtagtca tgaccaaaga tccgggtgcg gcctgtactg
     4681 agcagtttaa tattttaggg agttttttca ctacggatat tttgagtgat tatagccatc
     4741 tggatatagg taatggtctg ctattgaaga tatttcataa cgatggaaca gcaacggaat
     4801 ttaaccgctt ctcacaattt gcttcttttt catcgtctag tgcgccttcg gtcaccgcac
     4861 cattcagggc agaactgagt gcgaacccgg cagaaacggt tgttgaggga ccgtttagta
     4921 aagacgtaat cctgaaaatc acctataact agtatctaat acaaacacta aaacgggcca
     4981 tcaggcccgt tatatcagtg ctctaactcc agctctcttg cctgcatcat ctgttgacaa
     5041 taccaggcat aacgtgcgca aaaccaggtt ctatgttctt catccatgtt accagtaacg
     5101 gccagaatat cgaccgggcg accttctgcg tgcattctgg caaaactacg cgccaggaaa
     5161 tcgaaattat ttaaagaatt aagactatga tccataagca catcctccgg ttatcgcata
     5221 ccttttaagg ccatatgctt tttctgattt cagtattccc caatcagtgt agtgccttta
     5281 aacataacgt gcgtaaatat attgtccccg atcacacttt ttagtgaaaa ataaaaaacc
     5341 atattaaaag actttctctt ccagaacttc tctaacctgt gttattatta acacagataa
     5401 atgtaagcaa ggaaactatt acaaagtaaa tattgcgtca ctaaatggac attggagtga
     5461 tatatgattt tattcgccga ctataacacc ccttatcttt tcgctatttc ctttgtactg
     5521 ttgatcggcc tgttagaaat ttttgcgctt atctgcggtc acatgctctc cggtgctctt
     5581 gatgcacatc ttgaccatta tgattctata accacaggtc atattagcca ggcacttcat
     5641 tatctcaata ttggaagatt gccaactctc gtcgttctct gcttactggc tggttttttt
     5701 ggtcttattg gcatcctgtt gcagcatgcc tgcatcatgg tctggcaatc accactgtcg
     5761 aacctgttcg tggttcctgt cagtttactg tttacgatta ttgcggtgca ttataccggt
     5821 aaaatagttg cgccctggat tccacgcgac catagttcag ctattacaga agaagaatat
     5881 attggtagca tggcgttaat taccggtcat caagccactt caggtaatcc ctgcgaagga
     5941 aaactcaccg atcaatttgg ccaaatacat tatttactac tggagcctga agaaggaaaa
     6001 attttcacta aaggagacaa agtgttaatt atttgccgac tttctgcaac gcgatatttg
     6061 gcggaaaata atccctggcc ccaaatattg taatttatta atcaaaagga aatttaataa
     6121 tggatgatat tgttaattct gtgccctcct ggatgtttac cgcaattatt gccgtatgca
     6181 ttctgtttat tattggaatt attttcgcca ggctctatcg tcgcgcttcg gcagagcaag
     6241 cttttgttcg tactggttta ggtgggcaaa aagtggtaat gagcggtggc gcaatcgtga
     6301 tgccgatctt tcatgaaata atccccatca atatgaatac tctgaagctg gaagtcagcc
     6361 gctcaaccat tgatagcctg attacgaaag atcgtatgcg cgtcgatgta gtagtcgctt
     6421 tctttgtgcg ggtaaaacct tcagtagaag ggattgccac cgctgcccag acgctggggc
     6481 aacgcaccct gtcgcctgaa gacttacgta tgttggttga agataaattt gtcgatgccc
     6541 tccgtgcaac agctgcgcaa atgaccatgc atgagttaca ggatacccgc gagaactttg
     6601 tgcagggggt gcaaaataca gtggcagaag acctgtcgaa aaacggtctg gaactggaga
     6661 gcgtttcact taccaacttt aaccagacct cgaaagaaca tttcaatccg aacaatgcct
     6721 ttgacgccga aggtttaacc aaactgactc aggaaacaga gcgccgtcgc cgcgaacgta
     6781 acgaagttga acaggatgta gaagttgcgg tgcgtgaaaa aaatcgcgat gcgctatcgc
     6841 gcaagctgga gattgaacag caagaagcgt ttatgacgct tgagcaggag cagcaggtta
     6901 aaacccgtac tgccgaacag aatgcacgta ttgcggcttt tgaagctgaa cgtcgtcgtg
     6961 aagcagagca gacacgaatt ctggctgaac gacagattca ggaaacagaa atcgaccgcg
     7021 aacaggccgt ccgctcaaga aaggttgaag ctgaacgtga agttcgcatt aaagagatcg
     7081 aacagcagca ggtcaccgaa atcgctaacc agacgaaatc gatcgctatt gccgccaaat
     7141 cggaacaaca gtcccaggca gaagcgcgtg ctaatctcgc acttgcggaa gcggtaagcg
     7201 cccaacaaaa cgtagaaacc actcgccaga ctgccgaagc cgatcgtgct aaacaagttg
     7261 ccctaatcgc tgccgcgcag gatgcagaaa ccaaagcggt tgaactgacc gtgcgggcga
     7321 aagcagaaaa agaagccgca gagatgcagg cggcggctat cgttgagtta gccgaagcta
     7381 cacgtaaaaa gggtctggcg gaagcagaag cacaacgtgc gctgaacgat gctatcaacg
     7441 tactttctga tgaacaaacc agccttaaat tcaaactggc cttgttgcag gcgctgcctg
     7501 cggtaataga gaaatccgtt gagccgatga agtcaatcga cggtatcaag attattcagg
     7561 tcgatggtct gaatcgtggc ggcgctgcgg gtgatgcaaa cacgggtaat gtggggggcg
     7621 gaaacctggc ggaacaagca ttatcagccg ctctctctta ccgcacacag gcaccgctga
     7681 ttgactcctt gctcaatgaa attggcgttt caggcggctc actggcggca ttgacttcac
     7741 ccttaacctc aacaactccc gtcgaagaaa aagcagagta aaccctcttc caggaataat
     7801 ccctggccca aaaagccggg gattttttat atctgcgttc cgctaaaaag tgcaaatgat
     7861 caggttgttg cagcattttg cgtgacggct cggggaaggc aaaactgcat cagagaaagc
     7921 attgcgtggg gtctggcgct catcaacaat cggggagtca gcagggggct gaaacgggaa
     7981 agcccctccc gaagaagggg gccttacaga aggaaagggt tatgatgaag ctcgtcatca
     8041 tactgattgt gttgttactc gtaagtttcg cagcttatta acagccaatc agagggggga
     8101 gaaatcctcc ctcacccttg ttcctttact ttaggttgaa aaaaaatcag cgtcaagaag
     8161 gtttcattaa cacatatccc tggcccaaaa agccggggat tttttatatc tgcgttccgc
     8221 taaaaggtgc aaatgctcag gacgttgcag cgttttgcgt gaccgctcgg ggaaggcaaa
     8281 attgcctctg ggaaagcatt gcgcggggtc cggcgctcat caacaatcgg ggggcagcaa
     8341 ggggctgaaa cgggaaagcc cctcccgaag aaggggcctt gtataaggaa agggttatga
     8401 tgaagttcgt catcatactg gttgtgttgt tactgttaag tttcccgact tactaacaac
     8461 tcatcagagg ggggagaaat cctcccttac ccttgttcct ttactctagg ttgaaaaaac
     8521 aacagcgtca ataggcctgc catgtacgaa gcgagatctg tgaaccgctt tccggttagc
     8581 cttttttatc ctgttggatc ttcttgatga tgttggtcgt cgagcaaccg tcttcaaagt
     8641 tgagcaccaa cacttcgcca ccgttggccc agacttcttt actcccggca atctcttctg
     8701 gtttatagtc gccgcctttc accagcagat ctggcaagat cccggcgatc aagcgctgcg
     8761 gcgtgtcctc ttcaaacgac accacccagt cgaccgcttc cagtgcgccc agcacaatca
     8821 tacgctgttc gagcgggtta acggggcggg aatccccttt cagccgtttg gtggaggcat
     8881 cgctgttcac agcgacaatc aaacggtcac ccagtttacg ggcatttgcc agataagaga
     8941 cgtgcccggc gtgcaggatg tcaaagacac cgttggtcat caccactttt tcaccacgtt
     9001 tacgcgctgc cgctacggcc agcttcagtt cctcttcggt catcacgcca aagcctgtat
     9061 ctgcacgtcc acgtacagca ttttccagct cgatcggcga aaccgtggag gttcccagtt
     9121 tgccgaccac cacgccagcc gccgcattgg caaagaagca ggcttcttcc agcgaattac
     9181 ccgctgccag cgttgccgcc aggacgccaa tcaccgtgtc gcccgcaccg gtaacgtcat
     9241 acacttcctg cgcttgggtt ggcatatgca gcggcgcttt acccggttgc agcagcgaca
     9301 taccctgttc ggaacgggtc actaacagag ccgagagttc gtaatcggca atcagtttca
     9361 tgccgcgctc aacaatctct tcttcggtct tacatttacc gacaacagct tcaaattccg
     9421 agagattcgg cgttaacagc gtagcgccgc ggtagcgctc aaaatcggta ccttttggat
     9481 caatcagcac cggaacaccc gctttacgcg ccagttggat catctgctgt acgcttgcca
     9541 gcgcaccttt ggcgtagtca gaaagcacca gcgcgccaat cgaactcagc gcctgattaa
     9601 tccgctcgtg cagcggctgc ggatcaacac cttcgaaacc ttcttcaaaa tccagacgga
     9661 tcagctgttg gttgcgggaa agtacccgta atttggtaat ggtcggatgc gtcggtacag
     9721 aaacgaagtc gcatttgacg ttgacgtcgg ccagagattt actcagcgcg cgcgctgcat
     9781 cgtcaatgcc cgtcaacccg accaggcgtg cattagcacc gagagaagcg atattcatcg
     9841 ccacgttagc cgcgccgccc ggacgttctt cgatggtatt cactttaacc acgggcaccg
     9901 gcgcttccgg cgagatacga ctggtggggc cgtaccagta acgatccagc atcacatcac
     9961 caaccaccat cactcctgca cgttcaaact ctggcagcgt tactttcatt cctgtctcct
    10021 gagagattca aaatttgcgc gcgataatac catacttcat tcttccacca gccacttctg
    10081 ccagcttgcc cgcaccagtt cacgctctgc ggtgaagcaa tcctccgaca catggcccgg
    10141 caattcctgt aatgccagat gatgaagttc atcgcgaagc gtagtgtaag cacgggtcag
    10201 cgccatcgct tcctgctctt ccataatgtc gttttgcgcc agtagttcca gaatacgcac
    10261 gttgtctgac cagcgcgtta acttcggttt ttcatgagcg tagcgcaaca ccagatattg
    10321 ggtaataaat tcgatatcgg taattccccc ttcatcagct ttgatatcaa agcgatcgcg
    10381 atgtttattg ccgagatgag cgcgcatttt ctcgcgcatt tcccgcactt ccgtttgcag
    10441 agttttacct tcacgcggca gcgtcataat ctcgcgacgc actgcgtcaa agtgcgcggt
    10501 gagctgcgga tcgccgtaca ctacacgcgc acgcaccagc gcctgatgtt cccacgtcca
    10561 ggcctcgttt ttctgataat cggcaaatgc ttctgcggat gtcaccagca ttcccgccgc
    10621 cccggacgga cgcagtcgag catccacttc atacaaaatg ccggaagagg tacgcgtact
    10681 gaacagatgc ataatgcgtt gcgccagacg cagataaaac tgccgcccgt cgatttcccg
    10741 ctcaccgtca gtcatcgcat ccattgggca atcatggagg aagataaggt caagatcgga
    10801 actgtagcct aactcccagc cgcccagctt gccgtagccg accaccgcaa aaccacgccc
    10861 ttcgcgttcg ttcaggtgat tcggcttacc gtagcgggca accatttgaa cccacgcctg
    10921 ctgaacgacg gcatctatca tggcttccgc cagccaggtt aagtgatcgc tcactttcat
    10981 caccggtagc gtaccggcga tatccgctgc ggcgatgcgt aacagctgcg cctgtttgaa
    11041 ctgacgcagc gcctcaagct gttgctcttc gtcatcttcc ggcacgcgca gcaaatactg
    11101 gcgcaactca tcgcggtagg catcggtcgc cgtcggctgg taaagggtgt ttggatcgag
    11161 caattcatcc agcaataatg gataacgcgc cagctggctg gcaatcatcg gcgacgcggc
    11221 acacagagaa atcaaatgtt taagcgccgc ggggaattca ctgagcaatt ctaaataggt
    11281 ggtgcgggta acaatcccca ccagcaaggc ggtaatgcgc gacagcgtaa cggcagcgtc
    11341 ttcacgcgca cagacatcac ttagcagatg cggcatcaga tggtcgagca cctgacgtcc
    11401 tcgcggcccg atggtgcgct tatccagctc tttgcggaaa tcggcaatca gcgttagcac
    11461 ctgtttgcga tcatcctcgc taagatgcgc cagcactggc gtagtgtcat cttcctgcaa
    11521 cgcatcctgc cacagctcac gccactgttc cgacagcgac tcttcctgag tttcactttc
    11581 atcgtcgcca atcaattcat taaacacccg gcgcacattg gtcatatgtg cggtcagcgc
    11641 cccggtcagt tgcggccagt cagcaaagtc catcgcccac gccagccgcg cacgattaag
    11701 ctcatcagaa ggaagcgtct gggtttgttc gtcgttaatg ctttgcagca ggttttccag
    11761 acgccgcagg aacagatacg ccactcgcaa ttgttcagca tcgttttcag aaagcagatg
    11821 cagctcggca atggcgctga gcgttggcag taaagagcgc gattgcagcg acggttcgcg
    11881 tccgccgcga atgagctgga acacctgaac gataaattca atttcgcgaa tgccgcctgc
    11941 gccgagtttg atattgtcgg tcaaaccacg tcgacgcact tcacgggcaa tcatcccttt
    12001 catgttgcgc agcgactgaa tcacgctgaa atcgatgtaa cgacggaaaa caaacgggcg
    12061 cagcatcgca cgcaactcgt tagcatagac gccttcgcta tcgcccataa tccgcgcctt
    12121 gaccatcgcg taacgctccc agtcgcgccc ctgctcctgg taataatctt ccaacgcggc
    12181 aaagctcagc accagcgggc cactttcgcc aaacggacgc agccgcatat ccacgcgata
    12241 gacgaagcca tcctgcgttg gttgatccag cactttaatc agccgctgcc ccatgcgggt
    12301 aaaaaactgc gcgttatcca gttcccggcg tccaccctgc gtacaaccat gttccggcca
    12361 ggcaaaaatc agatcgatat cagaggagaa attcagctcc ccaccgccca gcttacccat
    12421 gcctaaaatc agcagcggtt gcgcttcgcc ctgcgcattg cacggcgttc cccactcgcg
    12481 gcagcaggcg tcatacagcc agtcacgcgc cgcaacaatc agcgtctccg ccagatagct
    12541 gagctgctgc aatatgctct cttcagtaac cagtgccagc gtttgcgccc aggcgatgcg
    12601 caccataatg cgccgccgga atagccgcag ctcgcgcatt aacccggctt cgtcactcac
    12661 attacagagc gcctcctgca accatgccgc gtaatgctgc cattcgtcgg cctgcggcgg
    12721 ttggctttcc agttccgtca gccactctgg atgcgcaatc acgctgtcct gcacaaaatc
    12781 actaaaagta agtactgact tcgcctgtgc gctaagtgat tcctcggcta aaggctctgg
    12841 cagccgctca acaacggtct gccagtactg ctgtaacggt gaagagagcg gcttcataag
    12901 cgattttatc cttgcctgat taacgttttc cgctgtgcaa ccagaacggt tcctgattgt
    12961 ttgcctcatt acggaaatgt tcaatttcga tgcgttgccc ggtcgcaata gcgtgatgca
    13021 gcccctgcca gttctccagc caggcttgcg cgacgacagg atcatagtaa cccgccagca
    13081 acagtattga gtcaatatca cgcgtcaggc gtggcaactg gtcacggtag cgatcgccta
    13141 acggctggca gaaaacgctt ttcagttcag cggcatggcg ggaaagatgg atatcggcaa
    13201 agcgtttgaa ggagtcgctg attttgccct gcgctttggc atctaaaaat ggctgccatg
    13261 ctttgcttac caaccattcg gtcaacgcca gcttcgccat tgccgtttcg gtagagtaga
    13321 ccgccgtcac ggcagacacc gcagaagcaa tggtcgcctc gcattgagtc agcagatcac
    13381 gtaagtgagt gctcgcttta cgcggcacaa taccaccgaa cagcatcagc gtatgacgga
    13441 ccaggctaat ggctgccagc acctgttctt tcgccgcatc gttgccgcgt acccacagtt
    13501 cttcatgata ctgccattgc gctaacgcca gctcgagcgc cgcttccagc ccctgttcca
    13561 catcggcttt tgccgcaaca tgcaaaatgg tggtcggttt gatttcacgc gccggattgc
    13621 cctgcgccag atgatagcca cgcgccgctt tgctcaggct gccctggcgt aatccggttt
    13681 gcgataccag ttggttcgcc agtttcagca ccgcgcgcgt gtcgccgcta agcagttcca
    13741 gttccagctc acagataggt tcagcaaatt cacccgcttt cacttccccc tggtcgaggg
    13801 cgatttcaat ttggctacca tcgaccgcca ccagccattt ttcgcgataa aaatcggtgc
    13861 tgaacagcgg ctgcacgcgg gaggcgagat cggcgggcaa ttcgccgttc ggccagactt
    13921 ccgtcggtaa ctgcgccagg tcgagcgtcg gttcgctcaa cgccacgtta tattccgggc
    13981 gctgatgtaa gccgcctgtc actcttcctg caactttcat ggtcatctca tagcgaccgt
    14041 tttcgccacg aatacgtaag cccatatcgt gcccacgcag ccagttatcc ggcgtttcgt
    14101 agtaaatatt cagcaactgc acggggtcat ggtgctcgcc gcccagcgta ttgagatggt
    14161 cacgcaacgc ctcaacggca ctgtgattaa caataaactt taattcgatt tcctgagcca
    14221 tggcctttac ttatcggtta tgtcacataa gtgacgatga acggcgaact taatgcgatc
    14281 ttttttgtca gtagatagta ttttgcgcca aattgccatg caacgggcaa tttgacgggc
    14341 gtaaaagttt gaagcagtgg caagacctga cacagaggat tccgattgat gtcgaatgct
    14401 ttgcgtagcg acactgatgc cactactatc gttccacttt ccatgacaat aacgacagcc
    14461 tgatgccaaa attacgcctg atcggattaa ctttactcgc acttagcgcg actgccgtct
    14521 cacacgctga agaaacgcgc tatgtttccg acgaactgaa tacctgggtc cgcagcggtc
    14581 cgggagatca ttatcgcctc gtgggcacgg ttaacgccgg cgaggaagtg accttattac
    14641 aaactgacgc caacaccaat tatgcccagg tgaaagacag ctctggccgt accgcctgga
    14701 tcccgttgaa acaacttagc actgagccaa gcctgcgctc ccgtgtgcca gatctggaaa
    14761 atcaggtcaa aaccctgacc gataaactca ccaatatcga taacacctgg aatcagcgca
    14821 ccgcagaaat gcagcaaaaa gtggcgcaga gcgacagcgt gatcaacggg ttaaaagaag
    14881 aaaatcagaa actgaaaaac gagctgattg tcgcgcagaa aaaggtcgat gccgccagcg
    14941 tacagctgga tgacaaacag cgcaccatca tcatgcaatg gtttatgtat ggcggtggcg
    15001 tgctggggct tggcttgctg ctcggtctgg tactgccgca cctgatccca agccgcaaac
    15061 gcaaagatcg ctggatgaac taaatcgcct tcttcgttgc actgtcttat tattaggaat
    15121 tgtgtatttg acgaagggat gatggcgtga agatttatct ggtcggtggt gctgttcggg
    15181 atgcattgtt agggctaccg gtcaaagaca gagattgggt ggtggtcggc agtacgccac
    15241 aggagatgct cgacgcgggc taccagcagg taggccgcga ttttcctgtg tttctgcatc
    15301 cgcaaacgca tgaagagtat gcgctggcac gtaccgaacg gaaatccggt tccggttaca
    15361 ccggttttac ttgctatgcc gcaccggatg tcacgctgga agatgatctt aagcgtcgcg
    15421 atctgaccat taatgcgctg gcccaggacg ataacggcga gattatcgac ccgtacaacg
    15481 gtctgggcga tctgcaaaat cgtctgttgc gccatgtttc ccccgctttt ggcgaagatc
    15541 cgttacgcgt attgcgcgtg gcgcgttttg ctgcgcgtta tgcccacctc ggttttcgta
    15601 ttgccgatga aactctggcg ttgatgcgcg agatgaccca tgcgggtgaa ctggaacacc
    15661 tgacgcctga acgggtatgg aaagagacgg aaagcgccct caccacccgc aatccacagg
    15721 tgttcttcca ggtactgcgc gattgcggcg cactgcgcgt tttattcccg gaaattgacg
    15781 cactgtttgg cgttccggcc cctgccaagt ggcatccgga aatcgatacg ggtattcata
    15841 ccttaatgac gctctcaatg gcggcgatgc tgagtccgca ggtcgatgtc cgtttcgcaa
    15901 ctttatgcca cgatctcggt aaagggctga cgccgccaga actctggccg cgtcatcatg
    15961 gtcatggccc ggcgggtgtt aagttagtgg aacaactatg ccagcgtctg cgcgtgccaa
    16021 atgaaattcg cgatttagcc agactggtgg ctgagtttca cgatctcatc cacaccttcc
    16081 caatgctgaa cccaaaaacc atcgtcaaat tatttgattc catcgatgcc tggcgtaaac
    16141 cgcagcgtgt cgagcaactg gcgctgacca gcgaggctga cgtgcgcggc agaaccggtt
    16201 ttgaatcagc ggactacccg caaggccgct ggttgcgcga agcctgggaa gtggcgcagt
    16261 cagtgccgac aaaagccgtc gttgaagcgg gatttaaagg tgtggagatt cgcgaggagc
    16321 tgacccgacg gcggattgcg gcggtagcca gctggaagga acaacgttgc ccaaagcctg
    16381 aatgagtatt gggcattttg ccggatgcgg cgtaaacgcc ttatccggct acatgtcaac
    16441 gacagttgta ggcctgataa gacgcgcaag cgtcgcatca ggcgttgatt gccggatgcg
    16501 gcgtgaacgc cttattcggc ctacgcaatc gttgacaacg ccaagcatcc gacactattc
    16561 ctcaattaaa agaacacgac atacaccgca gccgccacaa taaagcgata aatggcgaac
    16621 gggataaacg aaatgcgctt aatcaattgc aggaaggttt taatcgctat cagcgccacc
    16681 acaaaagcgg tgataaaccc aacggcaaac atcgggatat cgccgtttgt caggaagccc
    16741 cagcttttgt agagatcgag cgccgttgcg cccatcatca tcggcaccgc cagcaggaac
    16801 gaaaactcgg aagcagcgta acggctcacc cccatcagca tcccacctga aatggtcgcc
    16861 ccggaacggg agaaacccgg ccacagcgcc agacactgga aacagccaat cataaatgcc
    16921 tgacgatagg tcatatcatc cagacccggt gcgcgcggtt ctttcggctt caggcattcg
    16981 gcggcaatca gcaacaaacc gccaacgacc agcgcataca tcacatttat cgggttaaac
    17041 aatgacttaa tcgtgtcgtg gaacaacagc cccagtacca ccgccggaat catccccagc
    17101 aaaatgtgga tcagcgttaa acgacctttg ctttctcctt cgtgctgcaa cgggcggcca
    17161 aagtggatgc caatcaggcc aaacagacgc cgccagaaca tcactactac cgccagaatt
    17221 gatcctaact ggatcacaac ttcaaaggtt ttcgccgtgt cgccctcaaa ccccaacaaa
    17281 tgaccgacaa taatcatatg gcccgtgctg gataccggca gaaattctgt caatccttcg
    17341 accacaccca atattgccgc tatcagcagc gagtgcatat cgctcatcaa taaaccccta
    17401 aattattaaa atgtaccgct tgtccgaact actgcagtat gaccaggtta taaccgtttg
    17461 gtttaacagc tgtaaaatta attattttct ttcagattat tgccacgctc aatgattacg
    17521 ccaacattcg ccgcccgcgc cactgcgcct ggcttgctga gtttgatacg cacccacggc
    17581 gagttgaagc gtgctaacag cagctccgcc acctcttcag ccacgcgttc caccagcgca
    17641 aaacgcgccc cctcgacgtg gctgaccacc gtttctgcaa tgtcagcgta actgaggcaa
    17701 tccgccacat catcactttt cgccgcttta cggttatccc acgccatttc gatatcgaac
    17761 actaacttct gttcgatggt ctgttcccag tcgtaaacac caatagtggt gattaccgaa
    17821 agttgctcta taaatacaat atccatcacg tcctgcctgc tttttggcta accggatacc
    17881 acttccggcg aaatgtgcgt attatccaca gattcatcgt tgaacacgaa ttttcaaaac
    17941 ggaacagctt atgagtgcaa tcgcgcctgg aatgatcctc atcgcgtacc tctgcggctc
    18001 catttccagt gccattctgg tttgccgctt gtgtgggctg cccgatccgc gaaccagcgg
    18061 ctccggcaat ccaggcgcaa ccaatgtgtt acgtatcggt ggcaagggag cagccgtagc
    18121 agtactgatt ttcgacgttc tgaaaggaat gttgcccgtc tggggcgcgt atgaattagg
    18181 tgtcagcccc ttctggctag gcttaattgc catcgccgcc tgtcttggac acatctggcc
    18241 cgttttcttc ggttttaaag gaggaaaagg cgttgctacc gcttttggtg ccatcgcacc
    18301 cattggctgg gatctcaccg gagtaatggc gggaacctgg ttactgactg tgctattgag
    18361 cggatactcg tcgctgggag cgattgtcag tgcactgatt gctccatttt atgtctggtg
    18421 gtttaagcca caattcacct tcccggtttc gatgctctct tgcctgatcc tgctgcgtca
    18481 tcatgacaac atccagcgtc tgtggcgtcg tcaggagaca aaaatctgga cgaaattcaa
    18541 aagaaagcgc gaaaaggatc ccgagtgatt tctggtggat ctacatgacc tgatagcctt
    18601 catcgggctt gcccagccgt tgctggcacc atgccgccag aaattccacg cagacacgta
    18661 atttcatgct gcgatagagc ggctcccggt aaacagccca gatattggcg ctttgtgcat
    18721 actccggcaa tactcgcacc agtttgccac tctccagaaa cggcaacacg tcccactcgg
    18781 aacgcagcat aatccctttg ccctccagcg cccattgcag cacgatctcg ccgctattgg
    18841 aggaaagatg cccgctaacc ttcaccgatt ttttctcctg accgttcccc aactcccata
    18901 ttccatgggt catatcgcgc tctttggtca ccagacagtc atga
//
LOCUS       DAPHKZ010000086        18816 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.086, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000086 DAPHKZ010000000
VERSION     DAPHKZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18816
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.086"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(240..503)
                     /gene="cedA"
                     /locus_tag="RH288_003123"
     CDS             complement(240..503)
                     /gene="cedA"
                     /locus_tag="RH288_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HDV4032157.1"
                     /translation="MRLVKPVMKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVW
                     MLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQEGEVTE"
     gene            686..2947
                     /gene="katE"
                     /locus_tag="RH288_003124"
     CDS             686..2947
                     /gene="katE"
                     /locus_tag="RH288_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HDV4032158.1"
                     /translation="MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTP
                     PGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGP
                     TLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKIT
                     PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFV
                     HAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHT
                     FRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEY
                     ELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFH
                     PGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHR
                     MGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHP
                     RLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIEL
                     TDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALK
                     AKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDAN
                     YYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVEADSADGSFMDELLTLMAAHR
                     VWSRIPKIDKIPA"
     gene            complement(3205..3954)
                     /gene="chbG"
                     /locus_tag="RH288_003125"
     CDS             complement(3205..3954)
                     /gene="chbG"
                     /locus_tag="RH288_003125"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDV4032159.1"
                     /translation="MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAID
                     HAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQ
                     ELVSQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEQGIALRADRQMAFDLP
                     VNLRTTQGFSSAFYGEEISESLFLQVLDDAGHRGDRSLEVMCHPAFIDNTIRQSAYCF
                     PRLTELDVLTSASLKGAIAQRGYRLGSYRDV"
     gene            complement(3967..5319)
                     /gene="celF"
                     /locus_tag="RH288_003126"
                     /gene_synonym="chbF"
     CDS             complement(3967..5319)
                     /gene="celF"
                     /locus_tag="RH288_003126"
                     /gene_synonym="chbF"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDV4032160.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEGG
                     KAKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRF
                     AELLDGVASGQLKASSVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQA
                     EHYVNIPHHGQIDNIPADWAVEMTCKLGRDGATPHPRITHFDDKVMGLIHTIKGFEIA
                     ASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
                     "
     gene            complement(5424..6266)
                     /gene="chbR"
                     /locus_tag="RH288_003127"
     CDS             complement(5424..6266)
                     /gene="chbR"
                     /locus_tag="RH288_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HDV4032161.1"
                     /translation="MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDY
                     YEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
                     YREEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVALSAKSQEYLTRATQRYYGKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLT
                     EFNQ"
     gene            complement(6274..6624)
                     /gene="chbA"
                     /locus_tag="RH288_003128"
     CDS             complement(6274..6624)
                     /gene="chbA"
                     /locus_tag="RH288_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HDV4032162.1"
                     /translation="MMDLDNIPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQ
                     GDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGKMKVSLVLVHAQDHLMTSMLARE
                     LITELIELHEKLKA"
     gene            complement(6675..8033)
                     /gene="chbC"
                     /locus_tag="RH288_003129"
     CDS             complement(6675..8033)
                     /gene="chbC"
                     /locus_tag="RH288_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HDV4032163.1"
                     /translation="MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAM
                     FVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFI
                     GMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
                     EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQII
                     MDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQ
                     YGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLAL
                     PSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTM
                     PTGLGAFFNTNGSVAALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANAL
                     KF"
     gene            complement(8118..8438)
                     /gene="chbB"
                     /locus_tag="RH288_003130"
     CDS             complement(8118..8438)
                     /gene="chbB"
                     /locus_tag="RH288_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HDV4032164.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(8737..9075)
                     /gene="osmE"
                     /locus_tag="RH288_003131"
     CDS             complement(8737..9075)
                     /gene="osmE"
                     /locus_tag="RH288_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HDV4032165.1"
                     /translation="MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQAAK"
     gene            9277..10104
                     /gene="nadE"
                     /locus_tag="RH288_003132"
     CDS             9277..10104
                     /gene="nadE"
                     /locus_tag="RH288_003132"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDV4032166.1"
                     /translation="MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLV
                     LGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKKAPTADLEDDR
                     PSLPDEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK"
     gene            10334..11221
                     /gene="cho"
                     /locus_tag="RH288_003133"
     CDS             10334..11221
                     /gene="cho"
                     /locus_tag="RH288_003133"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HDV4032167.1"
                     /translation="MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGES
                     DTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQTIA
                     DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCW
                     PWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPL
                     LSGNYEITELDPANDQRAS"
     gene            complement(11181..11756)
                     /gene="ves"
                     /locus_tag="RH288_003134"
     CDS             complement(11181..11756)
                     /gene="ves"
                     /locus_tag="RH288_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="environmental stress-induced protein Ves"
                     /protein_id="HDV4032168.1"
                     /translation="MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIA
                     ANGEFSLFPGMERIVTLLEGGEMLLESADRFNHTLKPFQPFAFAADQVVKAKLTAGQM
                     SMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
                     GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ"
     gene            complement(11959..12444)
                     /gene="spy"
                     /locus_tag="RH288_003135"
     CDS             complement(11959..12444)
                     /gene="spy"
                     /locus_tag="RH288_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HDV4032169.1"
                     /translation="MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKF
                     GPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKVKAE
                     AQITKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
                     E"
     gene            complement(12774..13742)
                     /gene="astE"
                     /locus_tag="RH288_003136"
     CDS             complement(12774..13742)
                     /gene="astE"
                     /locus_tag="RH288_003136"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HDV4032170.1"
                     /translation="MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQG
                     ALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDM
                     NRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGV
                     LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFG
                     QNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFM
                     PFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS"
     gene            complement(13735..15078)
                     /gene="astB"
                     /locus_tag="RH288_003137"
     CDS             complement(13735..15078)
                     /gene="astB"
                     /locus_tag="RH288_003137"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HDV4032171.1"
                     /translation="MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRQAAKQ
                     GLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSS
                     ASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFS
                     VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREAS
                     EAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLAN
                     LRARVNGFMAIEVPATQVSVSDTVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGY
                     LNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFN
                     ALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG"
     gene            complement(15075..16553)
                     /gene="astD"
                     /locus_tag="RH288_003138"
     CDS             complement(15075..16553)
                     /gene="astD"
                     /locus_tag="RH288_003138"
                     /EC_number="1.2.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /protein_id="HDV4032172.1"
                     /translation="MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDAGAAQVEQACR
                     AARAAFPRWARLSLAERQVVVERFAGLLESNKAELTAIIARETGKPRWEAATEVTAMI
                     NKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
                     AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLF
                     TGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQR
                     CTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAW
                     QQLEAMGGRTLLAPRLLQSETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEA
                     IRMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGN
                     HRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR"
     gene            complement(16550..17584)
                     /gene="astA"
                     /locus_tag="RH288_003139"
     CDS             complement(16550..17584)
                     /gene="astA"
                     /locus_tag="RH288_003139"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HDV4032173.1"
                     /translation="MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAI
                     KTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     QEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPAQGDFPACLVANENYHHFRVVLVRTDPATERLILTAAQLDALKCHAGDRVRL
                     VRLCAEEKTA"
     gene            complement(17581..18801)
                     /gene="astC"
                     /locus_tag="RH288_003140"
     CDS             complement(17581..18801)
                     /gene="astC"
                     /locus_tag="RH288_003140"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylornithine/acetylornithine transaminase"
                     /protein_id="HDV4032174.1"
                     /translation="MSQPITRENFDEWMIPVYAPAPFVPVRGEGSRLWDQQGKEYIDF
                     AGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFC
                     NSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
                     LPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNA
                     LLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVG
                     THGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTLNHRYGLFSEIRG
                     LGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDR
                     FAAACEHFVSRGSS"
BASE COUNT         4750 a         5065 c         4468 g         4533 t
ORIGIN      
        1 catttacaat ataagtttaa gagcgacgcc acaggatgaa ctatcaaaaa tagctcatca
       61 tgattagcaa aacttaacca ttttaaaata aataaacaat taaagaaaaa agatcactta
      121 tttatagcaa tagatcgtca aaggcagctt tttgttacag gtggtttgaa tgaatgtagc
      181 aacgaaatac agaatttcag gtcatgtaac tcccggcaaa accgggaggt atgtaatcct
      241 tactcagtca cttccccttc ctggcggatc tgatttgccc aacgttgggc agattcaggc
      301 acagtaaacg ccggtgagcg cagaaatgac tctcccatca gtacaaacgc aacatatttg
      361 ccacgcagca tccagacatc acgaaacgaa tccatcttta tcgcatgttc tggcggcgcg
      421 ggttccgtgc gtgggacata gctaataatc tggcggtttt gctggcggag cggtttcttc
      481 attactggct tcactaaacg catattaaaa atcagaaaaa ctgtagttta gccgatttag
      541 cccctgtacg tcccgctttg cgtgtatttc ataacaccgt ttccagaata gtctccgaag
      601 cgggatctgg ctggtggtct atagttagag agttttttga ccaaaacagc ggccctttca
      661 gtaataaatt aaggagacga gttcaatgtc gcaacataac gaaaagaacc cacatcagca
      721 ccagtcacca ctacacgatt ccagcgaagc gaaaccgggg atggactcac tggcacctga
      781 ggacggctct catcgtccag cggctgaacc aacaccgcca ggtgcacaac ctaccgcccc
      841 agggagcctg aaagcccctg atacgcgtaa cgaaaaactt aattctctgg aagacgtacg
      901 caaaggcagt gaaaattatg cgctgaccac taatcagggc gtgcgcatcg ccgacgatca
      961 aaactcactg cgtgccggta gccgtggtcc aacgctgctg gaagatttta ttctgcgcga
     1021 gaaaatcacc cactttgacc atgagcgcat tccggaacgt attgttcatg cacgcggatc
     1081 agccgctcac ggttatttcc agccatataa aagcttaagc gatattacca aagcggattt
     1141 cctctcagat ccgaacaaaa tcaccccagt atttgtacgt ttctctaccg ttcagggtgg
     1201 tgctggctct gctgataccg tgcgtgatat ccgtggcttt gccaccaagt tctataccga
     1261 agagggtatt tttgacctcg ttggcaataa cacgccaatc ttctttatcc aggatgcgca
     1321 taaattcccc gattttgttc atgcggtaaa accagaaccg cactgggcaa ttccacaagg
     1381 gcaaagtgcc cacgatactt tctgggatta tgtttctctg caacctgaaa ctctgcacaa
     1441 cgtgatgtgg gcgatgtcgg atcgcggcat cccccgcagt taccgcacca tggaaggctt
     1501 cggtattcac accttccgcc tgattaatgc cgaagggaag gcaacgtttg tacgtttcca
     1561 ctggaaacca ctggcaggta aagcctcact cgtttgggat gaagcacaaa aactcaccgg
     1621 acgtgacccg gacttccacc gccgcgagtt gtgggaagcc attgaagcag gcgattttcc
     1681 ggaatacgaa ctgggcttcc agttgattcc tgaagaagat gaattcaagt tcgacttcga
     1741 tcttctcgat ccaaccaaac ttatcccgga agaactggtg cccgttcagc gtgtcggcaa
     1801 aatggtgctc aatcgcaacc cggataactt ctttgctgaa aacgaacagg cggctttcca
     1861 tcctgggcat atcgtgccgg gactggactt caccaacgat ccgctgttgc agggacgttt
     1921 gttctcctat accgatacac aaatcagtcg tcttggtggg ccgaatttcc atgagattcc
     1981 gattaaccgt ccgacctgcc cttaccataa tttccagcgt gacggcatgc atcgcatggg
     2041 gatcgacact aacccggcga attacgaacc gaactcgatt aacgataact ggccgcgcga
     2101 aacaccgccg gggccgaaac gcggcggttt tgaatcatac caggagcgcg tggaaggcaa
     2161 taaagttcgc gagcgcagcc catcgtttgg cgaatattat tcccatccgc gtctgttctg
     2221 gctaagtcag acgccatttg agcagcgcca tattgtcgat ggtttcagtt ttgagttaag
     2281 caaagtcgtt cgtccgtata ttcgtgagcg cgttgttgac cagctggcgc atattgatct
     2341 cactctggcc caggcggtgg cgaaaaatct cggtatcgaa ctgactgacg accagctgaa
     2401 tatcacccca cctccggacg tcaacggtct gaaaaaggat ccatccttaa gtttgtacgc
     2461 cattcctgac ggtgatgtga aaggtcgcgt ggtagcgatt ttacttaatg atgaagtgag
     2521 atcggcagac cttctggcca ttctcaaggc gctgaaggcc aaaggcgttc atgccaaact
     2581 gctctactcc cgaatgggtg aagtgactgc ggatgacggt acggtgttgc ctatagccgc
     2641 tacctttgcc ggtgcacctt cgctgacggt cgatgcggtc attgtccctt gcggcaatat
     2701 cgcggatatc gctgacaacg gcgatgccaa ctactacctg atggaagcct acaaacacct
     2761 taaaccgatt gcgctggcgg gtgacgcgcg caagtttaaa gcaacaatca aggtcgctga
     2821 ccagggtgaa gaagggattg tggaagctga cagcgctgac ggtagtttta tggatgaact
     2881 gctaacgctg atggcagcac accgcgtgtg gtcacgcatt cctaagattg acaaaattcc
     2941 tgcctgatgg gaggcggcgc aattgcgccg cctcaaatga tttacatagt gcgctttgtt
     3001 tatgccggat gcggcgtgaa cgccttatcc ggcctacaaa actgtgcaaa ttcaatatat
     3061 tgcaggaaac acgtaggcct gataagcgaa gcgcatcagg cagttttgcg tttgtcagca
     3121 gtctcaagcg gcgcagttac gccgcctttg taggaattaa tcgccggatg caaggttcac
     3181 gccgcatctg gcaaacatcc tcacttacac atcccgataa ctccccaacc gataaccacg
     3241 ctgagcgata gcacctttca acgacgctga tgtcaacaca tccagctccg ttaagcgtgg
     3301 gaaacagtaa gcactctgac ggatagtatt atcgataaac gccggatgac acatcacctc
     3361 cagcgaacga tcaccccgat ggcctgcgtc atccagcact tgcaggaaca gcgactcact
     3421 gatctcttca ccgtagaatg cactgctgaa tccctgggta gtgcgcaggt tgaccggcaa
     3481 atcaaacgcc atctgacgat ccgcccgcaa cgcaatgccc tgctctgccg caaacctggc
     3541 aacaatcggg aaaatctgcg ggaacatatg cacatgatga tggctatcaa gatgcgtagg
     3601 tttgcgtcca aatagctcaa tgaaacgcaa atactgactg acaagctcct gagtaatttc
     3661 ttccagcggt aaagcatctt cttctgccaa ctgccagatc cattttccca gcacaccatc
     3721 gcgggttaac cccggcatag ctgtcagtgg cttacccata gtaaggacaa agtgcatccc
     3781 tatggccaga ctcggttcat cacgactcaa ctgcaccgca tggtcaatag cctgcccatt
     3841 caccagcgcc gtcgtcgacg tgacaatccc attgcgacag gcctcgataa tgccgtagtt
     3901 ctgacctttg cttaagccaa aatcatcggc attaacaatc agtaagcgtt ccataatcag
     3961 cctcggttaa tgtgcttttt taagctctgc gatgcagtcg gcaaagtttg gcagccattt
     4021 ctcgtgcgcc agaatcatct cgcgtgccag cagctcagca tcgcgatcgg aatgcaccaa
     4081 cggactaagg tttagcgcca gtaacacatc gttaaattct ccgctaagtg cggcgttact
     4141 ggcagcaatc tcgaagcctt taatggtgtg aatcagcccc attactttat catcgaaatg
     4201 cgtaatgcgc ggatgtggcg tcgcgccatc gcgccccagc ttacaggtca tttctactgc
     4261 ccagtctgcc ggaatattat caatctgccc atgatgcggg atattaacgt aatgttctgc
     4321 ttgcttgtcg ttgtagatag cgttgatcac ttcgcatgct gcatcagagt aataagcccc
     4381 accgcgctgt tccagttctt tcggcttaac tttcagctca ggatttttat acagctcaaa
     4441 aagttgtttc tcgactttct gtactacctg cgctcgtgcg ccgcctttgt agtattcgcc
     4501 catttcaata gccagcatct ctttctgctt gaagtaatac agcagataag aacatggcag
     4561 cagattcaac gaacgaatta agccctcact aaatggcaga tcgaaaatat tttttacaga
     4621 ggacgctttt aactgccctg acgccacacc atcaagcaat tcggcaaagc gcgacttgcc
     4681 atttaccagc acatccttaa tgaacaccat atggttgagg ccgaacaaat cgatagataa
     4741 atcatcgctg tctttcagca tcagaacatc gcgaataaac atcttcatgc cgatcggaat
     4801 attacacacg ccgataaagc gtttaaatcc ggtatgacga taaacggctt cagtgaccat
     4861 tcccgccggg ttagtgaagt taatcaccca tgcattcgga caaagttctt cgacatcttt
     4921 tacgatgtca aaaatcaccg gaatggtacg cagaccttta aacaaaccgc ccgcgccgtt
     4981 ggtttcctga ccaagataac catgacttaa tggaatacgt tcatccagtt cacgcgccgg
     5041 taattggcca acgcgcagtt gggtagtaac gaaatcagca tctttcaatg cttcgcggcg
     5101 atccagcgtt ttataaagct tcatcgggac gccagcgtta tcaatcatcc gttggcagag
     5161 atcgaaaata atatccagtt tcgctttacc accttcgaca tccaccagcc ataattcgct
     5221 gaccggcaat tcgtgataac gcttaataaa tccttccagt aactccgggg tatagctgct
     5281 cccgccacca atagtgacga cttttaattt ctggctcata atttctccct tcagtacaga
     5341 atactgatat ctggcatatc tgcccccccg gacataaata atccagcaac aggacagata
     5401 tgtgaattgt caggtataac gacttactga ttaaattcag tcaatttctt acgatagctc
     5461 ttaggcgtaa aggacgttaa tttcttaaac gttttaataa acaaactcgg gctactataa
     5521 ccggcctcaa acgcaatatc cgtcactgaa tagttggtca tttccagttg ttttttggca
     5581 aaattaatac ggatttcatt aataatctgc attggcgttt tgccataata tcgttgagtc
     5641 gctcgcgtca aatattcctg tgatttggct gacaacgcca ccatattctc cagcgccgat
     5701 tcactaaact gctctttatc atgcatcttt tctaccgtac ttttcagcca ctgcggtaca
     5761 tcatcaatca cctgttcttc gcggtaatga cgtaaacggt taatgacata aaaagtaacc
     5821 atctcaacaa actcttccag ccctgtttcg cggaaattca atgaagaaat cactgtttcc
     5881 acataggtga gaaaagcgtt attggtccgg tatacctgcg aagcgacaaa gcaataaggc
     5941 aacaatggca ggtaatgctg ctcaaaaaag cgtttactga tcccaacgtt caatatgcgc
     6001 gtggcaccaa actcataaaa actttgatgg tgcgaaccta acggaataaa aacaaaatcg
     6061 ccccgttcca gtaacacgcg cttaccgtta atctcctgga aataacgccc ggttaatacc
     6121 agagtaaatt cataatagtc gtgctgatgc agtccgctga tactctcagt tttgttatag
     6181 ataaacacat ggaagttttt gccattaaac aactgctgtt ctcgggcagt ggcaatttcc
     6241 ggcgcgttaa tcactggctg catcatcgac tccttatgcc ttcagttttt catgaagctc
     6301 aattaattca gtaatcagtt cacgcgcaag catggacgtc attaaatgat cctgagcgtg
     6361 gaccagcacc agactcactt tcatcttacc ttcgcccgca tcgccttcaa tcagtttcgt
     6421 ctgtaccaga tgcgcttcat tcaatgccat ccgtgactga tccatcatgg cttttgctgc
     6481 ggcaaaatcg ccctgcttcg cctgtttcag tgccgcatac gccaggctgc gcgcttgtcc
     6541 ggagttgatg atcagcccca tcaccacttc ttccagctct tcagcttccg tttgcgtatc
     6601 gggaatgtta tcgagatcca tcatacatcg ttcctctctt ttcttaccgg cacgattacc
     6661 cgtaccggca tcgattaaaa tttcagggcg ttagcgatat cttcttcgct ctcttcttta
     6721 tcaatcgcat tttgtgcttt gttagccacc acaacaaagg gcagataaat taacgttgcg
     6781 atgccaaggt tgaagagtgc gaccagcaat gcggcgacgc taccgttggt gttaaagaag
     6841 gctcccagac cggttggcat ggtccacggt gcaatattgg tcaccggagg aataatgccc
     6901 atgtagtacg ctgcgagggt gattgccgcc agaatcggtt gtaccagtac aaacgggata
     6961 aacatcaccg ggttcatgat aattggcaga ccaaacagaa tcggttcgtt aatctggaag
     7021 atgccggacg gcagcgccag ttttgccacc tgacgataat cagcacggcg agaggcgata
     7081 aagatagcca ggatcaggcc taaagtcgca ccactgcccc caaggaaaat aaaggagtcc
     7141 agcatcggct tggcccagat atggaaggtc ttaccggctg ccagcgccgc ttcgacggaa
     7201 ccatattgct gataggtcgc gatattttcc agtgcccacg gcgtcataat gccgttgtcc
     7261 agtgcggtca gcgccagcgc gccatgaata ccgaagaacc agagcagtgg aacaaagatc
     7321 acataggccc agcccaccac gctacccaac gatgccagtg gggttgagat ggtatccata
     7381 atgatctgat ggaagttggt gccccaggta ttcaacgccc aggcaataat ccccatcacg
     7441 gaaagaataa taaagccggg aattaatgcc gagaaggaac gcgatactga agcaggtacg
     7501 ctgtcgggca gtttaatgac ccaattgcgg cggacaataa aggtaaacat ttctgccacc
     7561 accaggccaa taataatccc ggagatgata ttcgccccac ctaaccagtt tgcaccaacc
     7621 gcataggcct caccgacact atatggggtg acggtcataa atgctgcaac ggataacaac
     7681 ccagccgcca gcgcatcgac tttacgctct tctgccagcg ccatgccaat aaagaacggt
     7741 gccattaaag acattattcc taatgttccg ttatatacgt tgccgccaat acctttcaga
     7801 ccattaagtg tttcaatggt tgaggcgtcg aggcgaatac ctaaggaata aaaaaacgac
     7861 ccctccccaa agcttagaaa aacgttgtta attaatacaa acatggcccc cgcaagggtt
     7921 aacggcatta agcgaataaa gccatttttg attgcattaa cgtgtggctg ctttcctatt
     7981 ttaactgcaa aagggaggag taccttttca agcgatgcaa taacattact catagaaaaa
     8041 tacccttaaa aaccgcaatt taaatattgc ggtattgatt tatgaaataa ctctttgacg
     8101 ggaaaattta aaataaatta atttgctgcg gcttttttaa tcgctgcaac cgcagcctta
     8161 agcacgccta aaccatcgac tttgccataa agcagcgagt caattacttc aaccggtttg
     8221 ttgggtaaca aacgctggat ttcgggcaac atataagcaa tctgcggccc taataacacg
     8281 acatcggcat tctgaccttt ttcaccagcc agtgtttccg gaaatgcttc aataatgacc
     8341 ggaacttcat atttttctgc ctgtgcgcgc atttttgata ccagtaaaga ggtagacatg
     8401 cccgcagaac aaaacagata aatgtgtttc ttttccataa aactgccctc atcgacgatt
     8461 atctgtcagc cagacactcc gcaagcctta acctgcttcc atgctctggg taacttgcga
     8521 aaccaacatg actttttttg tggctgaaag gagtatacgg tatagacctg agcaatagta
     8581 tttctttgac cttataaatt gtttctcctt gacctgtggt tatgaccctc ttcacatttc
     8641 gggcaaataa ttcgcgaaga taattaagaa ctcaggccaa aaaaaaccgg cgcaatggcc
     8701 ggtttccgtt gttactcaag ctttcagacg aattgattac ttcgcagcct gtggatcagt
     8761 gtcgtattca gcacaggtct gataaccgga gttgatgaca tgtccggtat catctaacgc
     8821 gacaaagtag gtttctgctt taccatcacg ttgacccagg atgtaggtct ggcaagtacc
     8881 gcgagcatgg atcatgctca cttcagacga aggtttaccc gcaatttgtg caacctgcgc
     8941 ccggctcatg ccttttttga cgtctttcac cacaggctgt acaaactggt ctttggtacg
     9001 atcataagcc gtacaacccg ccagcatggt taataccgcc gctgcactca gaattcctgc
     9061 catattcttg ttcatattcc gtcctcttgt ttatcagcgt gttagataag cctggaatac
     9121 attgggcgct ttttcaagcc cgtgaacgaa acggctccgc tttcagagga ttcctgtatg
     9181 acgttttaac caccattcag cccgctgtcg cttgtcgttt cagtagcaac gggttagctt
     9241 taaggaagtt ttgtcttttc tgtctggagg ggttcaatga cattgcaaca acaaataata
     9301 aaggcgctgg gcgcaaaacc gcagattaat gctgaagagg aaattcgtcg tagtgtcgat
     9361 tttctgaaaa gctacctgca aacttatccg ttcattaaat cactggtgct cgggatcagc
     9421 ggcggtcagg actccacgct tgccggaaag ctgtgccaga tggcgattaa tgagctgcgc
     9481 ctggaaaccg gcaacgaatc actgcaattt attgccgtac gcctgcccta tggtgttcag
     9541 gccgacgaac aagattgcca ggatgccatt gcctttattc aaccggatcg cgtattaacc
     9601 gttaatatca agggcgcggt attggccagc gaacaggcat tgcgggaagc aggcattgaa
     9661 ctgagcgatt ttgtccgtgg caatgaaaaa gcgcgtgagc ggatgaaagc acaatatagc
     9721 attgcgggta tgaccagcgg tgtcgtggtg ggcaccgatc atgcagcaga agccattacc
     9781 ggattcttca ctaaatatgg tgacggcggt acggacatta atccgctgta tcgtctcaac
     9841 aaacgtcagg gtaaacagtt actggcggca ttagcttgcc cggaacacct ttataagaaa
     9901 gcgccaacgg ccgatctgga agatgatcgc ccttctctgc cagatgaagt ggcactcggc
     9961 gtgacctatg acaatatcga cgactatctg gaagggaaaa acgtacctca acaggtcgcc
    10021 agaacaatag agaactggta tctgaaaacc gaacataaac gccgtccgcc aattaccgtt
    10081 ttcgatgatt tctggaaaaa gtaataattt gcacatattg gattgtgcga aaaagagtaa
    10141 tttgttcacg ccggatgcgg cgtgaacgcc ttattcgacc tataaaacta tgcaaattca
    10201 atacattgca ggagtcgaat aggcctgaca ggcgtagcac gtcagacggt gtaacctttg
    10261 tcatcgaccc gcctcttttt taatcgcttc ccgcctgtta cactggatag ataaccagca
    10321 ttcggagtca acagtggtac ggcgtttaac ttctccgcgg ctcgaatttg aagctgcggc
    10381 aatttatgaa tatcccgaac atttacgttc attccttaat gacttaccca cccgaccagg
    10441 ggtgtatctg tttcatggtg aaagtgacac catgccgctc tatatcggca aaagcgttaa
    10501 catccgcagc cgcgtccttt ctcatttacg taccccggat gaagccgcca tgctacggca
    10561 atcccgacgg atcagctgga tatgtaccgc cggtgaaatc ggcgctctgc tccttgaagc
    10621 gcgattaatc aaagaacaac agccgctgtt taataaacgg ttgcgccgca atcgccagct
    10681 ctgtgccctg caattaaatg aaaagcgcgt cgatgtggtg tatgccaaag aggtggattt
    10741 ttcacgagcc cccaacctgt ttggcctgtt tgccaatagg cgcgcagctt tgcaagcatt
    10801 gcagaccatc gctgatgaac aaaaactttg ttatggcctg ctgggactgg aaccgttaag
    10861 tcgcggtcgt gcatgttttc gttcagcgct aaaacgttgc gccggagcat gctgcggtaa
    10921 agagagccat gaggaacatg cgctacgctt gcgccagtct ctggagcgtt tgcgggtggt
    10981 gtgttggcct tggcaagggg cggtggcgct gaaagaacag cacccggaaa tgactcaata
    11041 tcatattatt caaaactggc tgtggctggg ggcggttaat tcgctggaag aagcgacaac
    11101 gttaattcgg acacccgccg ggtttgatca cgacggttat aaaattcttt gtaagccgct
    11161 gctttccggt aactatgaaa ttactgaact tgatccggcg aatgaccagc gagccagttg
    11221 atttcactga acaacagttt accttgcggt tgtaaaagcc gcagggtgtg cctgccatcg
    11281 aaccagcacg cgccctggtc ggtagtgagc aatttatcgc ccagttgcca cgccccgtta
    11341 atcacaaaca ccaccccgcc gcgtgagcca aaggtagtaa acgtacgttc ggcaattctg
    11401 actttcgcct tacagacatc caggcgtgtc atgatgttga aatccatcga catctgccct
    11461 gccgtcagtt tcgcttttac cacctggtcc gctgcaaagg caaaaggctg gaacggtttt
    11521 aaggtatggt taaagcggtc tgcgctttca aggagcatct cgccgccttc cagcaacgtc
    11581 actatccttt ccatgccggg aaacaaagaa aactccccat tcgccgcgat ggatgcaatg
    11641 ctggcacgcc agtaaaaatc acgttttgcc ggtgggaacg tgcaaatttc gcgcgtttca
    11701 ccggcagcat ttcgccacag attcaccgac attttacgca tatcaaagta ttccatactc
    11761 gctcccggcc cgttcttttc attgttatcg ttcaggtaac cgtggatggt tatcggcaac
    11821 tcgggtgatt tacgttagtg gtgatcaggc tttttttaca actgtttgag aagagaaaag
    11881 aaaaccgccg atcctgtcca ccgcattact gcaaggtagt ggacaagacc ggcggtctta
    11941 agttttttgg ctgaaagatt attcagcagt tgcaggcatt ttaccttttg ccgctggacg
    12001 ttctgtcaga cgcttctcaa aattagcatt aaattgcttt ttctgttccg gcgtcaggat
    12061 gttgtaaatt ttgttctggg tttccatgtg cgccagcatg ttagctttgc gctgttcttc
    12121 catttttgtg atctgcgctt cagcttttac tttatcgaag gtatcgctgg caatgatgtc
    12181 atgcattgcg cggcgttctt ccagcggcgg acgtttcatc tggtcacgct ggcctttcat
    12241 gatttcgcgg atctgctgtt tctgcgcgtc ggtcaggttc aggtctttga acatcatgtc
    12301 ctgatgcgga ccgaacttgc ctttgtggtg catcatcggc ttcgcgtcag ccggtgctgc
    12361 ggtagtggtg tctgcggcat gggccaggtt agccgcgcca agagccaggg tagaggcaac
    12421 aaacagtgca gttaatttac gcatattcta tatccttcct ttcagttatt tattacggct
    12481 ttcttaagta gcgtgccgtg ttgacgagat taactttact gactttagcg tcaattaatc
    12541 agagcaacgg taaaacaatg aaagtgtaaa aaacactttt gcgccaatta tggagaaaaa
    12601 aagaaaattt gatggagagt gatgagagaa tattacaaca cgatgatttt gcagagatta
    12661 tgaagaacta taccggatga ctggtgataa ataaagcaaa taaccaggat taatctgtat
    12721 taatttataa gaaagcaact taatacccgc agaatgattt ctgcgggtaa gtattagctt
    12781 attttttcga gcattaatcc cgcgcgtaat cccaacgcta ccaacggatt agggaataac
    12841 acatactcta catcatgggt tacggtaaaa cgttcctctc cgtcctgcgc cagcaatgtt
    12901 cctttctcaa acggcataaa attcagcgtg tcacttgcca tatgcatttc gaaggacggc
    12961 gagtggcgag taatttgcga aaccacccga taacggagcg gcggtgttct cacgataccg
    13021 acactctcac cagatagcag cgcagcaatt gcgctggcag ttactgcaaa ctggcgaaga
    13081 tcgttttgcc caaagggcaa cgctttgcca agttccagcg tacaggccag cgcgccaaaa
    13141 tgtctggcgc tgaaatgggt aaacgtacca ccaggttcct gatggaacac cagcgcctcc
    13201 agccccgccg cacccagcca cgtcagaaat ttctcgtccc agggaatgtc gcgttgcggt
    13261 aatacaccga actgcggatg caaggagcca cgaattgcgg tatgtagatc aaggtgccag
    13321 cgcacagatt ctttgccctg gtcataaaaa tcttccaggc actgttccag ttcgcgcgcc
    13381 cgacaggttt ctccgctttc agcaaatagc tgccaacgac cgccaaacat tcgattcata
    13441 tcgctatggc aataacgttt cccttgcttc agcgcaggag gattcccgag gatcaccagc
    13501 aaccgccaac gtaacgggat ctcgccgtga gatatcgcgc caagcaacgc gtccagcatc
    13561 tccacaggtg ccgtctcatt accgtgtatt cccgctgaaa tcaccagtgc gccttgcggt
    13621 ggcgttaatg gcgtcagttc cagcacacca tcgcccagcc agcgccagcg aacgccgttg
    13681 atttctcgct cggtgataac cggtttttta cccgttaagg tcagagcaag aaaattatcc
    13741 attgccccct ccctcgcgct ggaacggata aaccgaaccg agattcagta attggctcaa
    13801 tacatccagt gcttcccgcc cttcgcgcag caattgcggg tcggccagat cggcagcagt
    13861 aaggcgatcg cggtagtaac gatccaccca gtcattgagc gcattaaaca gcgtatcgtt
    13921 catcatcacc gccggattca ccgcccggcg ttcttcttct gtcaatacca cccgcaaccg
    13981 caggcacgcc gggccgccgc cattcgccat gctttcacgt aaatcaaaga cttttagttc
    14041 gctaatcggg ttgtcagcgg caaggagttc attgagataa ccccatactc cggcgtgttc
    14101 ccgacactcc tgaggcagca ccaacatcat ggaaccatca tcgcggctca gcagttggct
    14161 gttaaacaga taggtagaca ccgtatcaga cacggaaacc tgagttgccg gaacttctat
    14221 cgccataaaa ccattgaccc gcgcacgcag gtttgccagt aactgtgact ggcgagcgaa
    14281 cgcctgttgg tggcaaaaca gcacctggcg gttactcacg gcaatcacgt cattatgaaa
    14341 aacgccctgg tcgataacgt ccgggttttg ctgggcgaaa atcacctgtt ggggattcac
    14401 ctgattcagc cttgccaccg cctcgctggc ttcgcgagtc tgtcgcgccg gataacggga
    14461 aggccgggta tcattgcctt cttctcgccc gtagacaaaa agttgcatac ccggttcacc
    14521 gtaatgaccg ccgagacgat tgtggtttgc cgccccctca tcaccgagca acgctacctg
    14581 tggcaacgcc gaatggacgc taaatttctc ttcgtcgtta aaaatcgctt ttaacagcga
    14641 ttcagtgacg ggcgcttcca gcgaacggtg aaatttattg ttcaggttgg caacggtgag
    14701 atgcactttg ccatccagcg tatcggcaga tggcgcgatc gttgccgcat tggctaccca
    14761 cattggcgaa gcggaactga cgctggaaag ccagtgcggt gcctggcgtg caactttttc
    14821 cagtacctgc tcatcgctac cactgaatcc caactgacgc agcaccggaa taaacggacg
    14881 ctcgtgcggc gggatcacgg cctgggggaa tcccgcatcg gcaagggctt tcattttcag
    14941 taagccctgt tttgccgcct gtcgcgggtt agacacctga aaacggtgac gggtagaggc
    15001 ttcattacca aacgacaggc cagcgtaatg atgcgtcagc cctaccagcc cgtcgaaatt
    15061 aacttcccag gcgttcatcg caccacctca tcggaaaaat ccagcccggg gttaagcgtt
    15121 gcgggcaaag ttaacgagtc cgactccagg ctcgccatag gccatgcgca gtaatctgcg
    15181 gcataccaag cgctggggcg atggttaccg gatgcaccaa tgccgccgaa tggcgcggta
    15241 ctggcagcac cagtaagcgg tttgttccag ttaacaatcc ccgcccgcgc ctccagcaac
    15301 agttgatcga atttttcccg ctcgggggaa accagaccgc aagagagtcc gaagcgagtg
    15361 ttattcgcca ttcgaatcgc ttcctcgaaa gaatcataac gccagacgcg caaaagcggc
    15421 ccgaacacct cttcatctgg tacgccagca acgcctgtca tttcaatgat ccccggcgtc
    15481 agcaacgatg tctctgattg taataagcgc ggcgcaagca gggttcgtcc gcccatcgct
    15541 tccagttgct gccaggcagt aaccacctgc tgtgcggcct gttcagaaat cagcccgcca
    15601 ataaacggct gcggttcgtc atcccagttg cccggcgtta atcgctggct gacggcaacc
    15661 agacgagcaa gaaacgcatc gccctgcgct ccgcttttga gcaataaacg gcgggcgcag
    15721 gtgcagcgtt gcccggctgt gacaaacgcc gactgaatgg tcagatggac agccgcgtcg
    15781 atatccgcca cctcatcgat aattagcgga ttattaccgc ccatctcaag ggcgagaatt
    15841 ttctccggct gaccggagag ctggcgatgc agctggtagc cggtattggc gctaccggta
    15901 aacagcaaac cgtcgagatc ctccagcgca ctcagcgcct gacccgtttc acgcccgccc
    15961 tgcaccaggt tcagtacgcc cggcggcaag ccagcctgct gccataaacg cattaccgct
    16021 tcgccactcc acggtgtcag ttcgctgggt ttaaagataa tggtgttacc tgccagcaat
    16081 gccggaacga tatgtccgtt cggcaaatga ccagggaaat tatacggccc aaacaccgcc
    16141 agcacgccgt gcgggcgatg tcgcaggctc gccgcaccgt ccggcatttc actacgctgc
    16201 tcgccggtac gaacgtgata cgccttaatt gatatcgcga ttttattgat catcgccgtc
    16261 acttcggttg ccgcttccca gcgcggctta cccgtttctc tggcaataat cgcggttaat
    16321 tcggctttat tgctttccag caatccggca aagcgttcga caacgacctg acgttcagcc
    16381 aatgagagcc gcgcccagcg cggaaacgcc gcacgggctg cccgacaagc ctgttcgacc
    16441 tgagcggcac cggcatcatt gccttgccat aacacctcgc ccgataccgg attacgcttc
    16501 acacgcgatg cgccctggcc cgttatccag tcaccgttaa tccataaagt catgctgttt
    16561 tctcctctgc gcacaggcgc accagacgaa cgcgatcccc tgcgtggcat ttgagggcat
    16621 ccagttgtgc ggcggttaaa atcaaacgct cggttgccgg atcggtacgc accagcacca
    16681 cgcggaaatg gtgataattt tcattggcga ccaggcaggc cggaaaatcg ccctgcgcag
    16741 gctgcccttc tgccacttcc accagccgac ttttacggat ggcgcgcacg cggtcgatgt
    16801 cacactcaag cgttggcccg ccgtcgaaga tgtcgatata gttgcggtaa cgaaaacctt
    16861 ctttctccag caccgcgcgg gcaggcgcgg tttgcggatg tacctgaccg atgacgtcct
    16921 gggcttcctg ggataaaaag tgggtataga tcggatgttt cggcatcagt tctgcaataa
    16981 atgccttttg cccggtgccg cagagaaaat cggcgcggct aaaatccatc gaaaagaagc
    17041 gtttaccgag gctttgccag aacggtgaat agccgtgttc gtcaatcacc ccgcgcattt
    17101 cagcaaccac tttgtcatta aacttgtcgc gaaaagccgc cataaacata aagcgcgatt
    17161 tcgacagcaa atagccgttg ccctctttgc gccagtccgg gtcgagaaac agcgtgcaca
    17221 gctcgctgct gccggtgtga tcgttactga gaaacagcgt cggcaatgcg ttatagacat
    17281 tcagctcttt tgaggcgtga accaacgtgc cgacgcgata gttgtaccag ggatcgttca
    17341 gcccaaccgc cacctcaatg gcacaaatcc ccgccacggt gcctgtctcg ctatcttcca
    17401 gcacgaacac atagccctgc tcacttttgg gcagttcgcc ttgccaggtt ttgattgccc
    17461 tttcgatacg cgccgaaagc gtggcttcat tggcgggaag cgacgtcagg ccgccgcccg
    17521 ttttgctggc aagctgcatc agcgccgaga catctgatcg ctcaacggga cggatgacca
    17581 tcatgatgaa cctcggctaa caaagtgttc gcaagcagct gcaaagcgat ccagtccggt
    17641 cgtcacctct tcttcgctga cattgagcgc aggcgcaaaa cgcaccacgt tgccacctgc
    17701 aatcagtacc atcacgcctg ctttcgccgc ttcctgagag atctgtttcg cttgcccggc
    17761 gtaatcggca ttcagcacac agccaatcaa caaacctaag ccgcgaattt cgctgaacaa
    17821 accgtagcgg tgattaaggg tattaagacg ctcaacaaac cagtcgtgac gctgtttaac
    17881 gccattaagc atctctggtg tgttgatgag ctccagcact ttgcctgcca ccgccgaggc
    17941 cagcggatta ccgccatagg tggtgccatg agtgccaacg gtcatcacgc gggcgcactc
    18001 ttcggttgcc aacaacgcac cgaccgggaa accgccgccc agcgctttgg cggtagttaa
    18061 cagatcaggc gtcacgccgt agtgcatata ggcatacagt tccccggtgc gcccgacgcc
    18121 ggtttgtact tcatcaaaaa tcaacagcgc attgtggcgg ttacacaatt cacgcagacc
    18181 ttgtaaaaac gcgttgctgg ctggcaccac accgccttcc ccctggatgg gttcgacaat
    18241 caccgcacag gtagagtcgt caatcagcgc gctggcagag ttaatatcgt tatatgcagc
    18301 atgacgaata tccgccggca gtggcgcaaa atcctgtgaa taggctggct gcccacccgc
    18361 actgacagta aacagcgtgc gaccatgaaa cgcatttttg aacgccacga tgccgctctt
    18421 atggctgccg tagcggtcgt gagcgaattt acgcgccagt tttagcgccg cttcgttggc
    18481 ttccgcaccg gagttacaaa agaagacgcg atcggcaaac gtggcgtcga tcaatttttt
    18541 cgccagtcgc agtaccggct cgttggtgta accgttgccg gtatgccaga acttactcgc
    18601 ctgttcgttc agcgcttcac gcagttccgg atgcgcatgg cccagcgcgt tcaccgcaat
    18661 gccacccgcg aagtcgatat actctttccc ctgctgatcc cacaagcgcg aaccttcgcc
    18721 acgtaccggt acaaagggtg ccggagcgta aacaggtatc atccattcat caaagttttc
    18781 acgcgtaatt ggctgagaca tagcgacctc tacagt
//
LOCUS       DAPHKZ010000087        18396 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.087, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000087 DAPHKZ010000000
VERSION     DAPHKZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18396
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.087"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            269..994
                     /locus_tag="RH288_003141"
     CDS             269..994
                     /locus_tag="RH288_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDV4032175.1"
                     /translation="MLPGCCKNGIFISKIPVMQAGLKEVMRTHFPEYEIISSASAEDL
                     TLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLM
                     CPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERK
                     VLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELN
                     LPSVYGDAAEWNTAELRREMSHS"
     gene            952..1629
                     /gene="bglJ"
                     /locus_tag="RH288_003142"
     CDS             952..1629
                     /gene="bglJ"
                     /locus_tag="RH288_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HDV4032176.1"
                     /translation="MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQ
                     ESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLI
                     GSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
                     LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCEA
                     SNVLHPY"
     gene            complement(1667..2455)
                     /gene="fhuF"
                     /locus_tag="RH288_003143"
     CDS             complement(1667..2455)
                     /gene="fhuF"
                     /locus_tag="RH288_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HDV4032177.1"
                     /translation="MAYRSAPLYEDIIWRTHLQPQDAGLAQAVRATIAKHREHLLEFI
                     RLDEPAPLNAMTLAQWSSPNALSSLLAVYSDHIYRNQPTMIRENKPLISLWAQWYIGL
                     MVPPLMLALLTQEKALDVSPEHFHAEFHETGRVACFWVDVCEDKNATPHSPQQRMETL
                     ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEK
                     TLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            2596..2832
                     /locus_tag="RH288_003144"
     CDS             2596..2832
                     /locus_tag="RH288_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313355.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HDV4032178.1"
                     /translation="MLQRTLGSGWGVLLPGLLIAGLMYADLSPDQWRIVILMGLVLTP
                     VMLYHKQLRHYVLLPSCLALIAAIMLMIMNLNQG"
     gene            complement(2871..2957)
                     /locus_tag="RH288_003145"
     tRNA            complement(2871..2957)
                     /locus_tag="RH288_003145"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2921..2923),aa:Leu,seq:cag)
     gene            complement(3266..4297)
                     /gene="rsmC"
                     /locus_tag="RH288_003146"
     CDS             complement(3266..4297)
                     /gene="rsmC"
                     /locus_tag="RH288_003146"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HDV4032179.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRA
                     HTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLL
                     PVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWG
                     EYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHS
                     PKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRA
                     IMTRQAKKG"
     gene            4400..4813
                     /gene="holD"
                     /locus_tag="RH288_003147"
     CDS             4400..4813
                     /gene="holD"
                     /locus_tag="RH288_003147"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HDV4032180.1"
                     /translation="MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPAHVRLVMVAN
                     DLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQ
                     VASPALTELRANPTARAALWQQICTYEHDFFPRND"
     gene            4782..5228
                     /gene="rimI"
                     /locus_tag="RH288_003148"
     CDS             4782..5228
                     /gene="rimI"
                     /locus_tag="RH288_003148"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDV4032181.1"
                     /translation="MNTISSLETTDLPAAYHIEQRAHAFPWSEKTFASNQGERYLNFQ
                     LTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM"
     gene            5243..5920
                     /gene="yjjG"
                     /locus_tag="RH288_003149"
     CDS             5243..5920
                     /gene="yjjG"
                     /locus_tag="RH288_003149"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HDV4032182.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGAITSLQLQHGRFESWAERLNVEPGKLNEAFINAMAEICTPLPGAVS
                     LLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
                     EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHNREQPEGIAPTWTVSSLHEL
                     EQLLCKH"
     gene            6011..7600
                     /gene="prfC"
                     /locus_tag="RH288_003150"
     CDS             6011..7600
                     /gene="prfC"
                     /locus_tag="RH288_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDV4032183.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWA
                     PAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     SRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSM
                     VNLRLAQERYPDVQFHQTREH"
     gene            7993..8598
                     /gene="osmY"
                     /locus_tag="RH288_003151"
     CDS             7993..8598
                     /gene="osmY"
                     /locus_tag="RH288_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HDV4032184.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVD
                     SSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEA
                     VKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVE
                     TTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK"
     gene            8725..8886
                     /locus_tag="RH288_003152"
     CDS             8725..8886
                     /locus_tag="RH288_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HDV4032185.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLV
                     SLFMGRKRP"
     gene            9008..10081
                     /locus_tag="RH288_003153"
     CDS             9008..10081
                     /locus_tag="RH288_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HDV4032186.1"
                     /translation="MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFDLYLGTSAGAQNLSAFICNQPGYARKVIMRYTTKREFFDPLRFVRGGN
                     LIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
                     RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQ
                     WFKRMERWLGDSSLQPLVNLVQHHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIAL
                     GSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTRHLVPVVTPESIVIPPAPVAND
                     TLVAEVSDAPQANDPTFNNEDLA"
     gene            10078..10860
                     /locus_tag="RH288_003154"
     CDS             10078..10860
                     /locus_tag="RH288_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDV4032187.1"
                     /translation="MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAE
                     NFARVQALAEKYQPLYAALGLHPGMLEKHSDVSLDQLQQALERRPAKVVAVGEIGLDL
                     FGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLPCTGVVHGFS
                     GSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQG
                     QPNRPEQAVRVFDVLCELRPEPEDEIAEVLLNNTYALFSVSG"
     gene            complement(11377..12240)
                     /locus_tag="RH288_003155"
     CDS             complement(11377..12240)
                     /locus_tag="RH288_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HDV4032188.1"
                     /translation="MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNHCGECVPQCPHQALQIVDGKVVWNAAVCEQCDTCLKRCPQHATPMAQSMSVDEV
                     LSHVRKAVLFIEGITVSGGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
                     WEKLLPVCDGAMLDLKAWGSECHQQLTGRDNQQIKRSICLLAERGKLAELRLLVIPGQ
                     VDYLQHIEELAAFIKGLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEPLADALKVRG
                     VGRLIFPALYL"
     gene            complement(12212..13762)
                     /locus_tag="RH288_003156"
     CDS             complement(12212..13762)
                     /locus_tag="RH288_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HDV4032189.1"
                     /translation="MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQL
                     PAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLANGSEWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPYVRILTQDEIDVRIKRFWRYLDRTLPDAFMHA
                     NIGPSDSPITRAILRADAELKQVSPNLTFIYDPEITPDDLLLEVAKNICECSKPHIAN
                     GPVHDKIFTKGGYGIVSCYNSLPLAGGGSTLVRLNLKAIAERSESLDDFFTRTLPHYC
                     QQQIAIIDARCEFLYQQSHFFENSFLVKEGLINPERFVPMFGMYGLAEAVNLLCEKEG
                     IAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISH
                     EQQMRFSQ"
     gene            14020..14799
                     /gene="deoC"
                     /locus_tag="RH288_003157"
     CDS             14020..14799
                     /gene="deoC"
                     /locus_tag="RH288_003157"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDV4032190.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVD
                     VVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
                     AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAI
                     ADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY"
     gene            14926..16248
                     /gene="deoA"
                     /locus_tag="RH288_003158"
     CDS             14926..16248
                     /gene="deoA"
                     /locus_tag="RH288_003158"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313368.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HDV4032191.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVT
                     MALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYL
                     PTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQ
                     VDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE"
     gene            16300..17523
                     /gene="deoB"
                     /locus_tag="RH288_003159"
     CDS             16300..17523
                     /gene="deoB"
                     /locus_tag="RH288_003159"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDV4032192.1"
                     /translation="MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEAD
                     NGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGH
                     WEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEGTFGLDKLYELCEIAREELTNGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMS
                     LLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLA
                     KYFGTSDMEYGKAMF"
     gene            17603..18322
                     /gene="deoD"
                     /locus_tag="RH288_003160"
     CDS             17603..18322
                     /gene="deoD"
                     /locus_tag="RH288_003160"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDV4032193.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGVDARVGNLFSADLF
                     YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
BASE COUNT         4414 a         4689 c         4947 g         4346 t
ORIGIN      
        1 aatgaatgtg atttctattt ttcattaagt attcctaaca acttaatgta gatattttaa
       61 atgtctccag gctatttcac caggttatca tttgatgcta accttctgac acatgcagtg
      121 gagttgttgt gcagcaggag tatgctgata tgaaagtgaa tgctaaggat aatttattcg
      181 cttaatctat taatttgctg gaaacattta aggaatgaat atcctgaata aaccatcatg
      241 atttttagac agtggatgtg gaggaaatat gttgccagga tgctgcaaaa atggaatttt
      301 tatcagtaaa atacctgtta tgcaagcagg gttaaaagag gtcatgagga ctcacttccc
      361 tgaatatgaa ataatatcca gcgcctctgc ggaggacctt accttattac aattacgtcg
      421 ttccggatta gtcattgctg atttagccgg tgaaagtgaa gatccacgtt ctgtttgtga
      481 acattattat tctttaatct cacaatatcg ggaaattcac tgggttttca tggtgtcacg
      541 ctcctggtat tcccaggcag tagaattgct catgtgccct acggcgacgt tattgtctga
      601 tgttgaaccc attgagaatc tggtcaagac cgtacgttcc ggcaatacgc acgcagagcg
      661 tatcagcgcc atgctgacct ctccggcaat gactgaaact catgatttta gctatcgctc
      721 cgtcattctc actctttcag agcgcaaggt actgcggcta ttaggtaaag gatggggcat
      781 caaccagata gcttcgttgc ttaagaaaag taataaaact atcagcgccc aaaaaaacag
      841 tgcgatgcgt cgactggcaa ttcacagcaa cgctgaaatg tatgcatgga taaatagcgc
      901 gcagggtgca agagaactta acttgccttc tgtttatgga gatgccgcag aatggaacac
      961 agccgaatta agaagagaaa tgtcgcactc atagaaaaat gcgtcatgag tagtatcggt
     1021 attgagagtt tattcagaaa gtttgcgggt aacccttata agctccatac ctataccagt
     1081 caggagtcat ttcaggatgc catgtcgcgg atctcgtttg cggcggtcat tttttctttt
     1141 tctgccatga gaagtgagcg cagagaggga ttatcttgcc tgactgaact ggcgattaag
     1201 tttccgcgta cccggcgttt agttattgcg gatgatgata ttgaagctcg gctgattggt
     1261 tcattgtcgc catcaccgct ggacggtgta ttaagtaaag cgtcaacgct ggagattttt
     1321 catcaggaac tctttttgtc attaaatggt gtacgtcagg cgaccgaccg actgaacaat
     1381 cagtggtaca ttaaccaaag ccggacgcta agccccacgg agagagaaat attgcgcttt
     1441 atgtcgcgtg gctactcaat gacacaaatt gccgagcagc ttaaacgcaa tatcaaaacg
     1501 atccgtgcac ataaatttaa tgtgatgtcg aaactgggcg tcagttctga tgcagggttg
     1561 ttggaggccg cagatattct gttatgtatg cggcattgcg aagcaagtaa tgtgttgcat
     1621 ccctattaat ccgcatgatg ccgggtttac ttccccggca gtgctttcat ttcagcgtac
     1681 aatcgccaca ttgctgcaca tccggtaagc gataacgctg gcagcaagtg cggcgcacca
     1741 gcaggccatc gcgcagtacc acggtacgcc agagtggatt atcttcaccg ttcgtgagcg
     1801 ttttctcaaa aaagagggca tggcgcagcg attcaaccgt cgcctcgccg agcagctgct
     1861 tcatctcagt gagataccag ttgatcaaat aaccggtatt actccagata agtttgccgt
     1921 tgatctctcc ggtcgcttct agtgcctgca caaccggaac cagcgcctgg ctgattaacg
     1981 tttccattcg ctgctgcggc gaatgtggtg ttgcgttttt atcttcacac acatcgaccc
     2041 agaaacaggc gacgcgtccg gtttcgtgaa actcagcatg gaaatgttcc ggcgacacat
     2101 ctaatgcctt ttcctgcgtc agtagcgcca gcattaatgg tggcaccatc aggccgatat
     2161 accattgtgc ccatagtgag atcagcggtt tgttctcgcg gatcatcgtt ggttggttgc
     2221 gatagatatg atcggaatag accgcgagta gagaacttag cgcattcggt gatgaccatt
     2281 gcgccagcgt catggcgtta agcggagcgg gttcatccag gcggataaac tcgagcaaat
     2341 gttcacgatg tttggcgatc gtcgcacgta cggcttgtgc aagcccagca tcctgcggct
     2401 ggagatgcgt tcgccagatg atatcttcat agagcggtgc ggaacgatag gccataatcg
     2461 ggatagtaat ctaaatgata atgattgcta atcctagcga taggtttacc cgatagcaag
     2521 ggatttctct ggcttgcaaa tgataaaaat tatcatatga tattggttat cattatcaat
     2581 gaaagagatg aaaccatgtt gcaacgtacg ctgggcagtg gctggggagt gttgctgccg
     2641 ggattgctga ttgcagggct gatgtatgcg gatttatcgc cggatcagtg gcggattgtc
     2701 attctgatgg gattagtatt gacgccggtg atgctgtatc acaaacagtt acggcattac
     2761 gttttgctac catcgtgcct ggcgcttatt gctgccatca tgctgatgat aatgaatttg
     2821 aatcagggat gaaaaatcaa ggaagaaaca agaaaggaag taaagataat tggtgcgagg
     2881 ggggggactt gaacccccac gtccgtaagg acactaacac ctgaagctag cgcgtctacc
     2941 aattccgcca ccttcgcata ccatcaattc ttaaaaagaa ttgctaccac ggaggcgcat
     3001 tctagtggtt ttcagctttt cgtcaatagt taattatcgc cggaggtgta attgctggaa
     3061 aaatgtccat caggaaacta acgtgcaggt ttggtagttt tgtaggtcgg ataaggcgtt
     3121 cacgccgcat ccgacacggt atttgggtgc agatgccaga tgcgacgcgg gcgcgtctta
     3181 tctggcctac gaagggctaa cgtgcaggtt ttgtaggtcg gataaggcgt tcacgccgca
     3241 tccgacacgg tattcggcga gataattaac ctttcttcgc ctggcgggtc ataatggcgc
     3301 gatacacctt gaaacgcccg gtttgcgcaa tcacttcatg gaagccaaat gtctcatcca
     3361 gcacgtccgg gtaaggcagg aaggcgttcg ctacaattcg cagctcgccg ccgctattaa
     3421 gatgacgcac cgcgccgcga atcagcgttt gcgccgcatc caggctggtt tgcatcccat
     3481 cgtggaacgg cgggttggag atgatcatat caaaacgacc tttcacctcg gaaaagacgt
     3541 tgctggcaaa gacttcacct tcaacaccgt tggccgcaag tgttgcgcgg ctggcttcta
     3601 ccgctggcgc agagacatcg cacaaggtga gacgaatttt cggcgaatgg cgcgcaaagg
     3661 caactgaaag cacacccgcg ccacagccga catccagcac tttacctttc gtgtgcgggg
     3721 ttaacgtcga gagcagcaac tggctaccga catccagacc gtcgcggcta aacacgccag
     3781 gcagcgtttt gaccgtcagg ccatcgacgc tgtattcgcc ccagaattta tcggcatcaa
     3841 ataccggctg tttttccaga cgaccaaaat agaggccaca gcgacgagcg ctgtcgactt
     3901 tattcaacgg cgcataatct gccagcatct gctcggcgct gcgcacgccg ctgcggttct
     3961 cgccaacgac aaaaatatct gtccccactg gcagcagaga aagtaaattc atcaactgga
     4021 actgggcttc cggtttgttc ttcggccagt agtaaatcag cgtatcgcaa tctgcgacgt
     4081 catccgccgt ggcgaccaga ctgaaacggg cgttatcccc catctggcgg cttaatacct
     4141 gccagtggtg gaattgctgg gtatgagcac ggctggccgc ggtatctaaa cgcgcgggca
     4201 ggtcatcctg taagtctccg gcaaacagaa tacggctttg ttcgaaatca tcactgtgac
     4261 gcagcaagac ttcacttgcc ggggtaaatg cagacatgga atgctcctca attgatactg
     4321 gcggcgatta tagccatatg ttggcgcggt atcgacgaat ttgctatatt tgcgcccctg
     4381 acaacaggag cgattcgcta tgacatcccg acgagactgg cagttacagc aactgggcat
     4441 tacccagtgg tcgctgcgtc gccctggcgc gttgcagggg gagattgcca ttgcgatccc
     4501 ggcacacgtc cgtctggtga tggtggcaaa cgatcttccc gccctgactg atcctttagt
     4561 gagcgatgtt ctgcgcgcat taaccgtcag ccccgatcaa gtgctgcaac tgacgccaga
     4621 aaaaatcgcg atgctgccgc aaggcagtcg ctgcaacagc tggcggttgg gtactgacga
     4681 accgctatca ctggaaggcg ctcaggtggc atcaccggcg ctcaccgaat tacgggcaaa
     4741 cccaacggca cgcgccgcgt tatggcaaca aatttgcaca tatgaacacg atttcttccc
     4801 tcgaaacgac tgatttacca gcggcttacc acattgaaca acgcgcccac gcctttccgt
     4861 ggagtgaaaa aacctttgcc agcaaccagg gcgagcgtta tctcaacttt cagttaacgc
     4921 aaaacggcaa aatggcggcg tttgcgatta cgcaagtggt gctggatgaa gctacattgt
     4981 tcaatattgc ggtcgatcct gactatcagc gtcagggatt gggaagggcg ctgctggaac
     5041 atctgatcga tgaactggaa aaacgcggcg tggcgacgct ctggctggaa gtccgtgcct
     5101 caaacgctgc cgccattgcc ctgtacgaaa gtttaggctt taacgaggcg acgattcgcc
     5161 gcaattacta ccccaccacg gacggtcgcg aagacgccat catcatggcg ttgccaatca
     5221 gtatgtaaga caaggtggaa taatgaagtg ggactggatt ttctttgatg ccgatgaaac
     5281 gctgtttacc tttgactcat tcaccggcct gcagcggatg tttcttgatt acagcgtcac
     5341 ctttaccgct gaagattttc aggactatca ggccgttaac aagcctctgt gggtggatta
     5401 tcaaaacggc gcgatcactt cattacagct tcagcacggg cgtttcgaga gctgggccga
     5461 acggctgaac gtcgagccgg gtaaactcaa cgaagccttt attaatgcga tggcggaaat
     5521 ctgcacgccg ctgccgggcg cggtttctct gcttaacgcc attcgtggca acgccaaaat
     5581 cggcatcatc accaacggct ttagtgcctt gcaacaggtg cgtctggaac gcacgggcct
     5641 gcgtgattac ttcgatttgc tggtgatttc cgaagaagtt ggcgttgcca aaccgaataa
     5701 gaaaattttc gattatgcgc tggaacaggc gggcaatcct gaccgttcac gcgtgctgat
     5761 ggttggcgac actgccgagt ccgatattct cggtggcatc aacgccgggc ttgcgacctg
     5821 ctggctgaat gcgcacaatc gcgagcaacc agaaggcatc gcgcccacct ggaccgtttc
     5881 ttcgttgcac gaactggagc agctcctgtg taaacactga ttgcctcccc cccgttgatg
     5941 ggtaaaatag ccgcaatttt tcgttttcaa caagcgcggc gcgatgccgc ttactcaaga
     6001 agaaagaatt atgacgttgt ctccttattt gcaagaggtg gcgaagcgcc gcacttttgc
     6061 cattatttct cacccggacg ccggtaagac taccatcacc gagaaggtgc tgctgttcgg
     6121 acaggccatt cagaccgccg gtacagtaaa aggccgtggc tctaaccagc acgctaagtc
     6181 ggactggatg gagatggaaa agcagcgtgg gatctccatt actacgtctg tgatgcagtt
     6241 tccgtatcac gattgcctgg ttaacctgct cgacaccccg gggcacgaag acttctcgga
     6301 agatacctat cgtaccctga cggcggtgga ctgctgtctg atggttatcg acgccgcaaa
     6361 aggtgttgaa gatcgtaccc gcaagctgat ggaagttacc cgtctgcgcg acacgccgat
     6421 cctcaccttt atgaacaaac ttgaccgtga tatccgcgac ccgatggaac tgctcgatga
     6481 agttgagaac gagctgaaaa tcggctgcgc accgatcacc tggccgatcg gctgcggcaa
     6541 gctgtttaaa ggcgtttacc acctttataa agacgaaacc tatctctatc agagcggtaa
     6601 aggccacacc attcaggaag tccgcattgt taaagggctg aataacccgg atctcgatgc
     6661 agcggtcggt gaagatctgg cacagcagct gcgtgacgaa ctggaactgg ttaaaggcgc
     6721 gtctaacgag ttcgacaaag agctgttcct tgcgggcgaa atcaccccgg tattcttcgg
     6781 tactgcgctg ggtaacttcg gtgtcgatca tatgctggat ggcctggtgg agtgggcacc
     6841 tgcgccgatg ccgcgtcaga ctgatacccg taccgtagaa gcgagcgaag acaaatttac
     6901 cggcttcgta tttaaaattc aggccaacat ggacccgaaa caccgcgacc gcgtggcgtt
     6961 tatgcgcgtg gtatccggta aatatgaaaa aggcatgaag ctgcgccagg tgcgcaccgc
     7021 gaaagacgtg gtgatctctg acgcgctgac ctttatggcg ggtgaccgtt cgcacgttga
     7081 agaagcgtat cctggcgata tcctcggcct gcacaaccac ggcaccattc agatcggcga
     7141 cacctttacc cagggtgaga tgatgaagtt caccggtatt ccgaacttcg caccagaact
     7201 gttccgtcgt atccgcctga aagatccgct gaagcaaaaa cagctactca aagggctggt
     7261 acagctttcc gaagagggcg cggtgcaggt gttccgtcca atctccaaca acgatctgat
     7321 cgttggtgcg gttggtgtgc tgcagtttga tgtggtggta tcgcgcctga agagcgaata
     7381 caacgttgaa gcagtatatg aatcagtcaa cgttgccacc gcccgctggg tagaatgtgc
     7441 agacgcgaag aaattcgaag agttcaagcg taagaacgaa agccaactgg cgcttgatgg
     7501 cggcgataac ctcgcttaca tcgctaccag catggtcaac ctgcgcctgg cgcaggaacg
     7561 ttatccggac gttcagttcc accagacccg cgagcattaa ttcttgcctc cagggcgcgg
     7621 tagccgctgc gccctgtcaa tttcccttcc ttattagccg cttacggaat gttcttaaaa
     7681 cattcacttt tgcttatgtt ttcgctgata tcccgagcgg tttcaaaatt gtgatctata
     7741 tttaacaaag taatgacatt tctgacggcg ttaaataccg ttcaatgcgt agatatcagt
     7801 atctaaagcc gtcgattgtc attctaccga tattaataac tgattcagag gctgtaatgg
     7861 tcgttattca tcacccatcg cttttgtgat ggcgaccatt gacttctgta gagggtgaag
     7921 tctctcccta ttcagcaatg caacctcgtg ttgccaggct caaattacga gcaaacatac
     7981 aggaataaat cgatgactat gacaagactg aagatttcga aaactctgct ggctgtaatg
     8041 ttgacctctg ccgtcgcgac cggctctgcc tacgcggaaa acaacgcaca gactaccaat
     8101 gaaagcgcag ggcaaaaagt cgatagctct atgaataaag tcggtaattt catggatgac
     8161 agcgccatca ccgcgaaagt gaaggcggcc ctggtggatc atgacaacat caagagcacc
     8221 gatatctctg taaaaaccga tcaaaaagtc gtgaccctga gcggtttcgt tgaaagccag
     8281 gcccaggccg aagaggcagt gaaagtggcg aaaggcgttg aaggggtgac ctctgtcagc
     8341 gacaaactgc acgttcgcga cgctaaagaa ggctcggtga agggctacgc gggtgacacc
     8401 gccaccacca gtgaaatcaa agccaaactg ctggcggacg atatcgtccc ttcccgtcat
     8461 gtgaaagttg aaaccaccga tggcgtggtt cagctctccg gtaccgtaga ttctcaggca
     8521 caaagtgacc gtgctgaaag tatcgccaaa gcggtagatg gtgtgaaaag cgttaaaaat
     8581 gatctgaaaa ctaagtaatt cgtcgtaatt cgtcctcccg aactttgtcg ggaggcgcga
     8641 tgtgcaccac actaaaaata tcgcattgag tgattttcac gctcatatca agcggtgaca
     8701 ttaactatgg taaaggagac gcttatgttt cgttggggca tcatatttct ggttatcgcg
     8761 ttaatcgccg ccgcacttgg gtttggtggt ctggccggta ccgctgcagg cgcagctaaa
     8821 attgtctttg tcgtcgggat tattctgttc ctggtgagtt tgttcatggg ccgaaaacga
     8881 ccctagattt cagaccatta agaaaatttt atccaaagcc agtccagcgg actggctttt
     8941 gcggttttag cgaataataa attgcgttac tttgtcattc tttcacaaca aaaacaggaa
     9001 ggcagaggtg gggcagcgaa tacctgtaac gcttggtaat attgcgccgt tgtcgctaag
     9061 gccgttccag cctggacgaa tagctctggt gtgcgaaggc ggcggacagc gtggaatttt
     9121 cacggctggc gtgctggatg agtttatgcg cgcgcagttt aatcctttcg atctttatct
     9181 cggcacatct gccggggcgc agaacctctc ggcgtttatc tgcaatcagc ccggttacgc
     9241 gcgcaaagtc atcatgcgct ataccacaaa acgcgaattt ttcgatccat tgcgctttgt
     9301 ccgtggagga aatcttatcg atctcgactg gctggtggag gccaccgcaa gccagatgcc
     9361 gttgcaaatg gataccgccg cgcggttgtt tgacagcggc aaatcgtttt atatgtgcgc
     9421 ctgtcgtcag gatgactacg cgccgaatta ctttttacca accaaacaaa actggctgga
     9481 tgtgattcgc gcctccagtg cgatacctgg cttttatcgt agcggagtgt cgctggaagg
     9541 cattaactac ctggatggcg ggatcagtga tgcgattccg gttaaagagg cggcaaggca
     9601 gggcgctaaa acgttggtcg tcatccgcac tgtgccgtca caaatgtact acacgccgca
     9661 gtggttcaaa cgcatggaac gctggctggg tgacagtagc ctgcagccgc tggtcaatct
     9721 ggtgcagcat catgaaacca gctatcgtga cattcagcaa tttattgaga aaccaccggg
     9781 caagctgcgg atattcgaaa tttatccacc gaaaccatta catagtatcg cgcttggcag
     9841 tcggattccg gcgctgcgtg aagactataa acttgggcgt ttatgcggtc gttatttcct
     9901 cgccacggtt ggcaagctat taactgaaaa agcgccgctt acccgccatc tggtgccagt
     9961 ggtgacgccg gaatcgatcg ttattccgcc tgcgccagtc gccaacgata cgctggttgc
    10021 cgaagtgagc gatgctccgc aggcgaacga cccgacattt aacaatgagg atctggcttg
    10081 atttgccgtt ttatcgatac ccactgccat tttgatttcc cgccgtttag tggcgatgaa
    10141 gaggccagcc tgcaacgcgc ggcacaagcg ggcgtaggca agatcattgt tccggcgaca
    10201 gaggcggaaa attttgcccg cgtgcaggcg ttagcggaaa aatatcaacc gctgtatgcc
    10261 gcattggggt tgcatccggg gatgttggaa aaacatagcg atgtgtctct tgatcagcta
    10321 cagcaggcgc tggaaaggcg tccggcgaag gtggtggcgg tgggggagat cggtctggat
    10381 ctcttcggcg acgatccgca atttgagagg cagcagtggt tactcgacga acagctgaaa
    10441 ctggcgaaac gctacgatct gccggtgatc cttcattccc ggcgtacaca cgacaaactg
    10501 gcgatgcatc ttaaacgtca cgatttaccg tgcactggcg tggttcacgg tttttccggc
    10561 agcctgcaac aggccgagcg gtttgtacag ctgggctaca aaatcggcgt aggcggtact
    10621 atcacctatc cacgcgccag taaaacccgc gatgtcatcg caaaattacc gctggcatcg
    10681 ttgttgctgg aaaccgacgc gccggatatg ccgctcaacg gctttcaggg gcagcctaac
    10741 cgaccggaac aggctgtgcg ggtgtttgac gtgctttgcg agttgcgccc ggaaccagaa
    10801 gatgagattg ccgaagtgtt gcttaataat acgtatgcgt tgtttagcgt tagtgggtag
    10861 tttacccttc gtaggcagca tccggcagtc ggcgcataat gcctgatgcg acgcttgtcg
    10921 cgtcttatca tgcctacagg tttgtgccga accgtaggcc ggataaggcg ttcacgccgc
    10981 atccggcagt tggcgcacaa tgcctgatgc gacgcttgac gcgtcttatc atgcctacaa
    11041 gtctgtgccg aaccgtaggc cggataaggc gtttacgccg catccggcag ttggcgcaca
    11101 atgcctgatg cgacgcttgt cgcgtcttat catgcctaca agtctgtgcc gaaccgtagg
    11161 ccggataagg cgttcacgcc gcatccggca gtcggcgcat aatgcctgat gcgacgcttg
    11221 tcgcgtctta tcaggcctac aggtttgtgc cgaaccgtag gccggataag gcgttcacgc
    11281 cgcatccggc agttggcgca caatgcctga tgcgacgctg gacgcgtctt atcatgccta
    11341 caagtctgtg ccgaaccgta ggccgcatcc ggcatgtcac aaatacagcg ccggaaatat
    11401 caaccggccc accccgcgca cctttaatgc atcagccaac ggctcaacgt cttccggcgt
    11461 ggcgctcgcc cagctttgcg cctcgccata cacgccgtgg gcatgaaacg cgttcaggcg
    11521 taccggaaca tcgccaagtc ccttgataaa cgccgccagt tcttcgatgt gttgcaaata
    11581 atccacctgg ccagggatta ccagcaaacg cagttccgcc agcttgccgc gctctgccag
    11641 caaacagatg ctgcgcttaa tctgctgatt atcgcgtccg gttaattgtt gatgacattc
    11701 gctaccccat gctttgagat cgagcattgc gccgtcacac accgggagta atttttccca
    11761 gccggtttcg ctcaacatgc cgttactgtc caccagacag gtgagatggc gcagttgcgg
    11821 atcgtttttg atagcagtaa acagcgccac tacaaacggc agttgggtcg tggcttcgcc
    11881 gccgcttacc gttatccctt caataaacag caccgctttg cggacatggc taagcacttc
    11941 gtccacgctc atggattgcg ccatcggcgt ggcatgttgc ggacacctct tcaggcaggt
    12001 atcacactgc tcgcagaccg cagcgttcca caccactttg ccgtcaacaa tctgcaacgc
    12061 ctgatgcgga cactgtggca cgcactctcc gcaatgatta cagcgcccca tcgtccacgg
    12121 attgtgacag tttttgcagc gcagattgca gccctgcaaa aacagagcca gacgactgcc
    12181 tggcccgtca acgcaggaga aggggataat cttactgact aaagcgcatc tgctgttcat
    12241 ggcttatcac gcgcggctgg cgttccagaa tacgagtgtt gcgtgcggct tcttcgccca
    12301 gccaggtggt gttggtgcgt gaaccttcgg cgcgatattt ttctaaatcc gacaaacgca
    12361 ccatataacc ggtaacgcga accagatcgt taccgctgac attggcggta aattcacgca
    12421 ttccggcttt aaaggcaccg aggcaaagct gtaccagcgc ctgcggatta cgtttgatgg
    12481 tttcgtcgag cgtcagaatg tcgctgatgc cggaataata ataagcatga tgcggggcga
    12541 cagtttgcag atgggtgatc ggatctggct catcgccata gggtaaacgc gcgcccggcg
    12601 tggtgccgat atcggaactg atccccgact gtgcgtgtaa catggcgcgt ttttgccagc
    12661 catatttcac gggggtattg gcgacaaact ccgccagttg cgcgctgatg cgataaccca
    12721 cttcatttgc ggcggcttct ttaccgtagc gcgcggcaat cccttctttc tcacacagca
    12781 agttaaccgc ttccgccagc ccatacatgc caaacattgg cacaaaacgt tcagggttaa
    12841 tcagcccttc tttcaccagg aagctattct caaagaagtg tgattgttga tagaggaatt
    12901 cacaccgcgc atcgatgatg gcgatctgct gctggcagta gtgcggtaga gtgcgcgtaa
    12961 agaagtcatc cagcgattcg ctgcgctcgg caatggcttt caggttaagg cgtaccagcg
    13021 tgctgccacc acccgccagc ggcagtgagt tgtaacagct cacaatcccg tagccccctt
    13081 ttgtgaaaat tttatcatgc accggaccgt tggcgatgtg cggtttgcta cattcacaga
    13141 tgttcttcgc cacttccagc agtaggtcat caggggtgat ttcaggatcg tagataaagg
    13201 tcaggttcgg tgaaacctgc ttcaactctg cgtctgcacg taagattgcg cgggtaatgg
    13261 gcgaatcaga cgggccgata ttggcgtgca taaaggcgtc tggcagggtt ctgtcgaggt
    13321 aacgccagaa acgttttatt cgaacatcga tctcgtcttg tgttagaatt ctaacatacg
    13381 gttgcaacaa cgcatccagt tgccccaggt agaccggcat cgatgtgacc gacggtacgt
    13441 ggtggtaaag aatggtcagc agagagagtg cgtcatcaag atctttcgcg ccttccagct
    13501 ccagccattc ggaaccgttc gccagaaaac gggcgtaatc gggtaagaca tagcgcggtt
    13561 tgtacggcgc atgaccttca aacatatcgc agattacacc ttcatccagc gcgcggcggg
    13621 cttcggcagg aagctgtggg taaggcagat tgttttctgc ttccagtgcc agaaaatggc
    13681 gcttctgctc cgggctaagc actgggctgg tgacaatttg ctggcaacgt tgttgcagtg
    13741 cattttcatg agaagtgggc atcttctttt ccttttatgc cgaaggtgat gcgccattgt
    13801 aagaagtttc gtgatgttca ctttgatcct gatgcgtttg ccaccactga cgcattcatt
    13861 tgaaagtgaa ttatttgaac cagatcgcat tacagtgatg caaacttgta agtagatttc
    13921 cttaattgtg atgtatatcg aagtgtgttg cggagtagat gttagaatac taacaaactc
    13981 gcaaggtgaa ttttattggc gacaagccag gagaatgaaa tgactgatct gaaagcaagc
    14041 agcctgcgtg cactgaaatt gatggacctg accaccctga atgacgacga caccgacgag
    14101 aaagtaattg ctctgtgtca tcaggccaaa accccggtcg gcaataccgc cgctatctgt
    14161 atctatcctc gctttatccc gattgctcgc aaaacactga aagagcaggg caccccggaa
    14221 atccgtattg ctacggtaac caacttccca cacggtaacg acgacatcga aatcgcgctg
    14281 gcagaaaccc gtgcggcaat cgcctacggt gctgatgaag ttgacgttgt gttcccgtac
    14341 cgcgcgctga tggcgggtaa cgagcaggtt ggttttgacc tggtgaaagc ctgtaaagag
    14401 gcttgcgcgg cagcgaatgt actgctgaaa gtgatcatcg aaaccggcga actgaaagac
    14461 gaagcgctga tccgtaaagc gtctgaaatc tccatcaaag cgggtgcgga cttcatcaaa
    14521 acctctaccg gtaaagtggc tgtgaacgcg acgccggaaa gcgcgcgcat catgatggaa
    14581 gtgatccgtg atatgggcgt agaaaaaacc gttggtttca aaccggcggg cggcgtgcgt
    14641 actgcggaag atgcgcagaa atatctcgcc atcgcagatg aactgttcgg tgctgactgg
    14701 gctgatgcgc gtcactaccg ctttggtgct tccagcctgc tggcaagcct gctgaaagcg
    14761 ctgggccacg gcgacggtaa gagcgccagc agctactaag taagatgctt tacgcctgat
    14821 gcgctgcgct tatcaggcct acgagacgta tctacccgta ggccggataa ggcgtagacg
    14881 catccggcaa aagccgcctc atactctttt cctcgggagg ttaccttgtt tctcgcacaa
    14941 gaaattattc gtaaaaaacg tgatggtcat gcgctaagcg atgaagaaat tcgtttcttt
    15001 atcaacggta ttcgcgacaa cactatctcc gaagggcaga ttgccgccct cgcgatgacc
    15061 attttcttcc acgatatgac aatgcctgag cgtgtctcgc tgaccatggc gatgcgagat
    15121 tcaggaaccg ttctcgactg gaaaagcctg catctgaatg gcccgattgt tgataaacac
    15181 tccaccggcg gcgtcggcga tgtgacttcg ctgatgttgg ggccgatggt cgcagcctgc
    15241 ggcggctata ttccgatgat ctccggtcgc ggcctcggtc atactggcgg tacgctcgac
    15301 aaactggaat ccatccctgg cttcgacatt ttcccggatg acaaccgttt ccgcgaaatt
    15361 attaaagacg tcggcgtggc gattatcggt cagaccagct cactggctcc ggcggataaa
    15421 cgtttctacg cgacccgtga tattaccgca accgtggact ccatcccgct gatcaccgcc
    15481 tctattctgg cgaagaaact ggcggaaggt ctggacgcgc tggtgatgga cgtgaaagtg
    15541 ggtagcggcg cgtttatgcc gacctacgaa ctctctgaag cccttgccga agcgattgtt
    15601 ggcgtggcta acggcgctgg cgtgcgcacc accgcgctgc tcaccgacat gaatcaggta
    15661 ctggcctcca gtgcaggtaa cgcggttgaa gttcgtgaag cggtgcagtt cctgacgggt
    15721 gaatatcgta acccgcgtct gtttgatgtc acgatggcgc tgtgcgtgga gatgctgatc
    15781 tccggcaaac tggcgaaaga tgacgccgaa gcgcgcgcga aattgcaggc ggtgctggac
    15841 aacggtaaag cggcagaagt ctttggtcgt atggtagcgg cacaaaaagg cccgaccgac
    15901 ttcgttgaga actacgcgaa gtatctgccg acagcgatgc tgacgaaagc agtctatgct
    15961 gataccgaag gttttgtcag tgaaatggat acccgcgcgc tggggatggc agtggttgca
    16021 atgggcggcg gtcgtcgtca ggcatctgac accattgatt acagcgtcgg ctttactgat
    16081 atggcgcgtt tgggcgacca ggtagacggt cagcgtccgc tggcggttat ccacgcgaaa
    16141 gacgaaaaca gctggcagga agcggcgaaa gcggtgaaag cggcaattaa acttgccgat
    16201 aaagcaccgg aaagcacacc aactgtctat cgccgtatca gcgaataacg gtatactgat
    16261 ctgatcattt aaatttgaag cactgagtac ggagaacata tgaaacgtgc atttattatg
    16321 gtgctggact cattcggcat cggcgctaca gaagatgcag aacgctttgg tgacgtcggg
    16381 gctgacaccc tgggtcatat cgcagaagct tgtgccaaag gcgaagctga taacggtcgt
    16441 aaaggcccgc tcaatctgcc aaatctgacc cgtctggggc tggcgaaagc acacgaaggt
    16501 tctaccggtt tcattccggc gggaatggac ggcaacgctg aagttatcgg cgcgtacgca
    16561 tgggcgcacg aaatgtcatc cggtaaagat accccgtctg gtcactggga aatcgccggt
    16621 gtcccggttc tgtttgagtg gggatatttc tccgatcacg aaaacagctt cccgcaagag
    16681 ctgctggata aactggtcga acgcgctaat ctgccgggtt acctcggtaa ctgccactct
    16741 tccggtacgg tcattctgga tcagctgggc gaagagcaca tgaaaaccgg caagccgatt
    16801 ttctatacct ccgctgactc cgtgttccag attgcctgcc acgaaggaac ctttggcctg
    16861 gataaactct acgaactgtg cgaaatcgcc cgtgaagagc tgaccaacgg cggctacaac
    16921 atcggtcgtg ttatcgctcg tccgtttatc ggtgacaaag ccggtaactt ccagcgtacc
    16981 ggtaaccgtc acgacctggc tgttgagccg ccagcaccga ccgtgctgca gaaactggtt
    17041 gatgaaaaac acggtcaggt ggtttctgtc ggtaaaattg cagacatcta cgccaactgc
    17101 ggtatcacca agaaagtgaa agcaactggc ctggacgcgc tgtttgacgc caccatcaaa
    17161 gagatgaaag aagcgggtga taacaccatc gtcttcacca acttcgttga cttcgactct
    17221 tcctggggcc accgtcgcga cgtcgccggt tatgctgcgg gtctggagct gttcgaccgc
    17281 cgtctgccgg agctgatgtc tctgctgcgc gatgacgaca tcctgatcct cactgctgac
    17341 cacggttgtg atccgacctg gaccggtact gaccacacgc gtgaacacat tccggtactg
    17401 gtttacggcc cgaaagtaaa accgggctca ctgggtcacc gtgaaacctt cgcggatatt
    17461 ggtcagactc tggcaaaata ttttggtact tctgatatgg aatatggcaa agccatgttc
    17521 tgataatggg tgcggcttga tgccctcacc ccggccctct cccacaggga gagggtgaaa
    17581 acatgttgat aaggataaaa caatggctac cccacacatt aatgcagaaa tgggcgattt
    17641 cgctgacgta gttttgatgc caggcgaccc gctgcgtgcg aagtatattg ctgaaacttt
    17701 ccttgaagat gcccgtgaag tgaacaacgt tcgcggtatg ctgggcttca ccggtactta
    17761 caaaggccgc aaaatttccg taatgggtca cggtatgggt atcccgtcct gctccatcta
    17821 caccaaagaa ctgatcaccg atttcggcgt gaagaaaatt atccgcgtgg gttcctgtgg
    17881 cgcagttctg ccgcacgtaa aactgcgcga cgtcgttatc ggtatgggtg cctgcaccga
    17941 ttccaaagtt aaccgtatcc gttttaaaga ccatgacttt gccgctatcg ctgactttga
    18001 catggtgcgt aacgcggtag acgcggctaa agcactgggt gttgatgctc gcgtgggtaa
    18061 cctgttctcc gctgacctgt tctactctcc ggacggcgaa atgttcgacg tgatggaaaa
    18121 atacggcatc ctcggcgtgg aaatggaagc ggctggtatc tacggcgtcg ctgcagagtt
    18181 tggcgcgaaa gccctgacca tctgcaccgt gtctgaccac atccgcactc acgagcagac
    18241 cactgccgct gagcgtcaga ccaccttcaa cgacatgatc aaaatcgcac tggaatccgt
    18301 tctgctgggc gataaagagt aattgtgttt cgctgaaagg cgaacgtcgt gttaagccgg
    18361 agcaggagac tgctccggct ttttagtatc tattca
//
LOCUS       DAPHKZ010000088        18297 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.088, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000088 DAPHKZ010000000
VERSION     DAPHKZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18297
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.088"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            95..613
                     /locus_tag="RH288_003161"
     CDS             95..613
                     /locus_tag="RH288_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HDV4032194.1"
                     /translation="MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTR
                     WPALSGPPKLCIFSSSRFSTALQENAATSLPYLPVIIHTQQEAMISGCNGFYFGNESP
                     TFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
                     DVLMLARKKNDG"
     gene            603..1829
                     /gene="dgcN"
                     /locus_tag="RH288_003162"
     CDS             603..1829
                     /gene="dgcN"
                     /locus_tag="RH288_003162"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HDV4032195.1"
                     /translation="MMDNDNSLNKRPTFKRALRNISMTSIFITMMLIWLLLSVTSVLT
                     LKQYAQKNLALTAATMTYSLEAAVVFADGPAATETLAALGQQGQFSTAEVRDKQQNIL
                     ASWHYTRKDPGDTFSNFISHWLFPAPIIQPIRHNGETIGEVRLTARDSSISHFIWFSL
                     AVLTGCILLASGIAITLTRHLHNGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFH
                     RFALDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDA
                     RKTSALLFLDGDNFKYINDIWGHATGDRVLIEIAKRLAEFGGLRHKAYRLGGDEFAMV
                     LYDVQSESEVQQICSALTQIFNLPFDLHNGHQTTMTLSIGYAMTIEHASAEKLQELAD
                     HNMYQAKHQRAEKLVR"
     gene            1845..2327
                     /locus_tag="RH288_003163"
     CDS             1845..2327
                     /locus_tag="RH288_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDV4032196.1"
                     /translation="MIKHLVAPLVFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAG
                     DWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNE
                     GLSLKRANVVADAWAMGGQIPRSNLTTQGLGKKYPIASNKTAQGRAENRRVAVVITTP
                     "
     gene            complement(2403..2750)
                     /gene="rplS"
                     /locus_tag="RH288_003164"
     CDS             complement(2403..2750)
                     /gene="rplS"
                     /locus_tag="RH288_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDV4032197.1"
                     /translation="MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(2792..3559)
                     /gene="trmD"
                     /locus_tag="RH288_003165"
     CDS             complement(2792..3559)
                     /gene="trmD"
                     /locus_tag="RH288_003165"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDV4032198.1"
                     /translation="MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
                     GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            complement(3590..4138)
                     /gene="rimM"
                     /locus_tag="RH288_003166"
     CDS             complement(3590..4138)
                     /gene="rimM"
                     /locus_tag="RH288_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDV4032199.1"
                     /translation="MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLE
                     EGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLTTRSIEVDWDPGF"
     gene            complement(4157..4405)
                     /gene="rpsP"
                     /locus_tag="RH288_003167"
     CDS             complement(4157..4405)
                     /gene="rpsP"
                     /locus_tag="RH288_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDV4032200.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA"
     gene            complement(4654..6015)
                     /gene="ffh"
                     /locus_tag="RH288_003168"
     CDS             complement(4654..6015)
                     /gene="ffh"
                     /locus_tag="RH288_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDV4032201.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDF
                     LEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPE
                     IIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            6182..6973
                     /locus_tag="RH288_003169"
     CDS             6182..6973
                     /locus_tag="RH288_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417102.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HDV4032202.1"
                     /translation="MPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVC
                     HAIALEARILPDGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLALATFMPNEYITHLEATPGMLVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKL
                     AFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIVQQLIS"
     gene            6994..8280
                     /locus_tag="RH288_003170"
     CDS             6994..8280
                     /locus_tag="RH288_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDV4032203.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVPRSEIIGID
                     INDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKETMLRAA
                     DEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE"
     gene            complement(8335..8928)
                     /gene="grpE"
                     /locus_tag="RH288_003171"
     CDS             complement(8335..8928)
                     /gene="grpE"
                     /locus_tag="RH288_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDV4032204.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKI
                     ANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSL
                     DRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA"
     gene            9051..9929
                     /gene="nadK"
                     /locus_tag="RH288_003172"
     CDS             9051..9929
                     /gene="nadK"
                     /locus_tag="RH288_003172"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HDV4032205.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIA
                     HELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLT
                     DLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            10015..11676
                     /gene="recN"
                     /locus_tag="RH288_003173"
     CDS             10015..11676
                     /gene="recN"
                     /locus_tag="RH288_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDV4032206.1"
                     /translation="MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMT
                     ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLA
                     NSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQ
                     IAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQ
                     QLDDQADSQETLALAVTKHHQQALEIARALHQQRQQYAEELAQLITDSMHALSMPHGQ
                     FTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKE
                     TDGAMTETHMQSLNKKARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            11825..12166
                     /gene="bamE"
                     /locus_tag="RH288_003174"
     CDS             11825..12166
                     /gene="bamE"
                     /locus_tag="RH288_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417107.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HDV4032207.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVS
                     KIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLT
                     NIDNKPALSGN"
     gene            complement(12228..12518)
                     /locus_tag="RH288_003175"
     CDS             complement(12228..12518)
                     /locus_tag="RH288_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HDV4032208.1"
                     /translation="MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRT
                     DIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK"
     gene            complement(12508..12945)
                     /gene="ratA"
                     /locus_tag="RH288_003176"
     CDS             complement(12508..12945)
                     /gene="ratA"
                     /locus_tag="RH288_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010376629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin RatA"
                     /protein_id="HDV4032209.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCTGSRILESTP
                     GQMTAAVDVSKAGISKTFTTRNQLTSNQSILMNLVDGPFKKLIGGWKFTPLSQEACRI
                     EFHLDFEFTNKLIELAFGRVFKELAANMVQAFTVRAKEVYSAR"
     gene            13116..13598
                     /gene="smpB"
                     /locus_tag="RH288_003177"
     CDS             13116..13598
                     /gene="smpB"
                     /locus_tag="RH288_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDV4032210.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
                     "
     gene            13813..14175
                     /gene="ssrA"
                     /locus_tag="RH288_003178"
     tmRNA           13813..14175
                     /gene="ssrA"
                     /locus_tag="RH288_003178"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            14404..15618
                     /locus_tag="RH288_003179"
     CDS             14404..15618
                     /locus_tag="RH288_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_143212653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HDV4032211.1"
                     /translation="MYMSVFHNWLLDIASGNYFIYIKRLSANDTGATGGHQVGLYIPS
                     NIVEKLFPSINHTRELNPSVFLTAHVSSHDCPDTQARAIYYNNRYFGKTRNEKRITRW
                     GRGSPLQNPENTGALTILAFRLNEQNTDCSEVDIWVCVNPDEEDIIESAIGEIIPGTL
                     ISGPAGQILGGLSLQQTPVNHKYVIPEDWKKRFPSGNEIIQYAAGHYAKNSKDPDEQL
                     IDRRRVEYDIFLLVEELHVLDIIKKGFDSVDEFIALANSVSNRRKSRAGKSLELHLEK
                     LFIEHGLRHFSTQAVTEGNKKPDFLFPSAEAYHNVEFPVENLRMLAVKTTCKDRWRQI
                     LNEADKIHQVHLFTLQEGVSSAQYREMKDAGVRLVVPSTLHKKYPEAVREELITLGAF
                     ITELIELYAELS"
     gene            complement(15653..17056)
                     /locus_tag="RH288_003180"
     CDS             complement(15653..17056)
                     /locus_tag="RH288_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDV4032212.1"
                     /translation="MLKEAEAEEKLRQENDKKLIEKVLEIYDQKYVAELLRKVGKNEW
                     SRETINRWINGKCLPKSLTSVEESLLRKMLPEPPANHPEYAFRFIDLFAGIGGIRKGF
                     EAIGGQCVFTSEWNKDAVRTYKANWFNDEQVHKFNLDIREVTLSDKTDVLETDAYAYI
                     DEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDVARIIRAKKPA
                     IFVLENVKNLKSHDKGKTFKVIMETLDELGYEVADAAEMGKNDPKIIDGKHFLPQHRE
                     RIVLVGFRRDLNIHKGFTLRDISRFYPEHRPSFGELLEPVVDSKYILTPKLWEYLYNY
                     AKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMATGEADFMNES
                     NQARRPRRLTPRECARLMGFEKPGGKPFRIPVSDTQSYRQFGNSVVVPVFEAVARLLE
                     PYILKAVSADAGKTGQP"
     gene            17490..18263
                     /locus_tag="RH288_003181"
     CDS             17490..18263
                     /locus_tag="RH288_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032213.1"
                     /translation="MDITEFPSGVIEHLGWYVYRLIDPRDGSTFYVGKGKGNRVFAHM
                     RGEVAATDDDELLSNKLKQIREIRLAGLEVIHVIHRHGMTDEKTAYEVEAALIDAYPG
                     LTNIMNGAGSNEFGAAHVKELIATYQPETITFHHKALMISVNRSAKDSELYDAVRFSW
                     RINVSRASQAEVILATVRGIVRGVFIADKWLKSTRENFPTMKYWDEDPDFEATQSSRY
                     GFEGREAPPEIANLYLGKKIPDELRKKGAMSPVRYSPNF"
BASE COUNT         4762 a         4686 c         4223 g         4626 t
ORIGIN      
        1 cacattgatg acggtcgcat gaaaaaatga tattttaatg agcattctga aaaaatatcg
       61 atgcatttcg agcgaagatg gtggggatcc ctgaatgcgt ttttctcacc gactgttctt
      121 acttctgatt ctcctgctga cgggagcacc aatactcgct caggagcctt ctgacgttgc
      181 gaaaaacgtg cgtatgatgg tttccggtat tgtcagttac acccgctggc ctgcgctatc
      241 agggccacca aagttatgta tcttttcatc ttcacgtttt agtaccgccc tacaagagaa
      301 tgccgcgaca tctttgcctt atctgcctgt catcattcac actcaacaag aggcgatgat
      361 ttcaggctgc aatggttttt attttggcaa cgagtcaccg acattccaga tggaattaac
      421 cgaacaatat ccgtcaaagg cgttattatt aattgccgaa caaaataccg agtgcattat
      481 tggtagcgcc ttttgtctga tcatccacaa taatgacgtc agatttgccg taaacctgga
      541 tgccttatcg cgtagcggtg taaaggtcaa cccggatgtc ttaatgctcg cacggaagaa
      601 aaatgatgga taacgataat tctcttaata agcgccccac gtttaaaaga gcattacgca
      661 acatcagtat gaccagcata tttatcacta tgatgctgat ctggttgctg ctttccgtga
      721 cctcggtgct gaccctgaaa cagtacgcgc aaaaaaacct ggcactgaca gcagcaacaa
      781 tgacttacag tctggaagca gctgtcgttt ttgccgatgg ccctgcagca actgaaacac
      841 tggcagcgct gggccagcaa gggcaatttt caactgcaga agtacgtgat aagcagcaaa
      901 atattctggc atcctggcat tacacccgta aggatccagg cgatactttc agtaatttca
      961 taagccactg gctcttccct gcccccatca ttcagccgat tcgtcacaat ggtgaaacca
     1021 ttggcgaagt acgcttaacc gctcgcgaca gttcaatcag ccattttatc tggttttcgc
     1081 tcgccgtact gaccggttgt attctgctgg catcaggcat cgcaattacc ctcacccgcc
     1141 atttgcacaa tggcctggta gaagcgctga aaaatatcac cgatgtcgta catgatgtgc
     1201 gttccaaccg caatttttcc cgacgagttt cggaagaacg tatcgctgag tttcaccgct
     1261 tcgctctcga cttcaacagt ctgctggatg aaatggaaga gtggcagctt cgtttacagg
     1321 ctaaaaatgc gcagcttcta cgtaccgcgc tacatgaccc attaaccggg ctggctaacc
     1381 gcgcagcgtt tcgtagcggc atcaacacgt tgatgaacaa ttccgatgcc cgaaaaacgt
     1441 cggcgttact atttcttgat ggcgataatt tcaaatacat caatgatatc tggggtcatg
     1501 cgacgggcga tagagtcttg attgaaatcg caaaacggtt agctgaattt ggcgggctgc
     1561 gacataaagc ataccgcctg ggcggcgatg aattcgctat ggtgctctat gatgtacagt
     1621 cggaatctga agtgcagcag atatgttcag cactgacaca aatctttaat ctcccgtttg
     1681 atcttcataa tggccatcag accaccatga cattaagcat tggttacgcg atgaccattg
     1741 agcacgcctc tgcggaaaaa ttacaagagc ttgccgatca caatatgtat caggccaaac
     1801 accagcgtgc cgaaaagctg gtgagataac aaggatatat cgatatgata aagcacctgg
     1861 tagcccccct ggttttcacc tcactaatac tgactggctg ccagtcccct cagggaaagt
     1921 ttactcctga gcaagtcgcc gctatgcaat cttatggatt tactgaatcc gccggcgact
     1981 ggtcgctggg cttatcagat gccattctgt tcgcaaaaaa tgactacaaa ttgctcccgg
     2041 aaagccagca acagatccaa accatggcag ctaaattggc ctcgacaggg ctaacacatg
     2101 cccgtatgga tggacacacc gataactatg gtgaagacag ttacaacgaa ggcttatcat
     2161 tgaaacgggc gaatgtcgtg gccgatgcat gggctatggg tggacaaatt ccacgcagca
     2221 atctcaccac acagggttta ggaaaaaaat atcccatagc cagtaacaag accgcccagg
     2281 gccgcgccga gaaccgccgc gtcgcagtgg tgattactac cccttaaaac accagcaaac
     2341 agataaaaaa gggccagcca attggccagc ccttcttaac aggatgtcgc ttaagcgaaa
     2401 tcttagttaa gacgctcttt gatacgagca gccttaccag tacgctcacg caggtagtac
     2461 agtttagctt tacgaacagc accacgacgt ttgacagaaa tgctgtcaac taccggagag
     2521 tgagtctgga agacacgctc aacgccttcg ccgttggaaa ttttacgaac agtgaatgca
     2581 gagtgcagac cgcggttacg aatagcgata accacgccct cgaatgcctg cagacgtttt
     2641 ttggaacctt caacaaccca tactttcact tccacggtat cacccggacg gaaggaaggt
     2701 acgtcctgct tcatctgctc ttgttcaagt tgcttaataa tgttgctcat aatttaatct
     2761 cttatcctgg gtaaactgat atctcggggg cttacgccat cccatcatgt ttatgttgct
     2821 gttgtgcgtg ttccgttttg aactccgcca gcaaccttgc ttgctcttca gtcagagcca
     2881 ggttttccag aagttcaggt cttctaagcc aggtacggcc cagcgactgt ttcaaacgcc
     2941 agcgacgtat ctcggcatgg ttgcccgaca gtaacactgg cggaacttcc atcccttcta
     3001 acacctcagg ccgcgtatag tgcgggcaat ccagcaatcc ttcagcaaag gaatcttccg
     3061 ttgccgaggc ttcatgtccc agtactcccg gaataaaccg ggaaacggag tcaatcagcg
     3121 tcattgctgg taactcacca ccactgagaa cgtaatcgcc gattgaccat tcttcgtcaa
     3181 tttcggtttg gatcacgcgc tcatctatac cttcgtagcg accgcacacc agaatcaatt
     3241 tttgattcgt tgccagttcg ctgacgcccg cttgatcaag cttgcgtccc tgtggtgaca
     3301 gataaatcac ctttgcgcct tcacccgccg cggcttttgc tgcatgaatg gcgtcccgca
     3361 agggttgcac catcattaac atccccggtc cgccgccgta aggacgatcg tccacggtac
     3421 ggtgccggtc atgcgtgaag tcgcgaggac tccagctctg gatgctcagc aggccatttt
     3481 taactgcccg gccagttacc ccgtaatcgg taattgcgcg gaacatttca ggaaacaggc
     3541 taattatgcc aatccacata gcgccgtctt ttaccgttta tccggtggtt taaaaaccag
     3601 gatcccaatc tacttcgatt gaacgagtag tgagatcgac tttcttgata acctgcccat
     3661 cgaggaacgg tacgagacgt tccttgatac caaacgcatc tttcaggttt gccttaatga
     3721 cgagaacgtc attagatccg gtttccatca tatcgacgac tttaccgaga tcgtagcctt
     3781 cagtggttac tacctggcag cccatcaggt ctttccagta gtagtccccc tcttcaagct
     3841 gaggcagctg cgatgaatcc acgacaattt cacaattcgt cagcaggttc gccgcatcac
     3901 gatcgtcaac gcctttcagc ttgatgatca tgtcctgatt gtggtgcttc cagctttcca
     3961 gctggacttg ctgccactga cccgccttct ggataaacca gggctgatag tcaaaaatgc
     4021 tttcggcgtc ttcggtggaa gaaaacactc tgagccaccc acgaataccg taagacgaac
     4081 ccatttttcc caaaacgatg ggatcaacag gtgcttgcgc ggtgagttgt ttgctcatca
     4141 tgaccaccgt gacagattaa gctgctttgt ttacttcttt gatcagcgca gcaacgcgat
     4201 cagaaatagt tgcgccctgg ccaacccagt gagcgatgcg atccagatcc aggcgagtgc
     4261 cttcttcttt ttcgctagcg attgggttga agaaaccaac gcgctcgatg aagcgaccgt
     4321 tgcgtgcatt acggctgtca gcgacaacaa cctggtagaa cggacgcttt ttagcgccgt
     4381 gacgtgctaa acgaatagtt accataacat cctcttgtgt gaataaaaca accggacccc
     4441 atcgaggaac ggagtccggt gtcatattaa aagcccgaaa attttactca tttttgcggg
     4501 aattgcaatc aacagttgct aactctgctg taaaaggccg tcggcggtgc agccagtttg
     4561 gtgccggagt gcgcgcagtc accggagcgt acacgcagta cgtgaggatg acgagcacat
     4621 cccggtgcca aaatggcaaa caagccaggc cgattagcga ccagggaagc ctgggggcat
     4681 catacccttc atgcttctca tcatcttcgc cattccgccc ttcttcattt tcttcatcat
     4741 gcgctgcatg tcgtcgaact gtttcagaag acggttaacg tcctgcacct gcataccgca
     4801 accggcagca atacggcgtt tacgcgaacc tttgatgatt tctggcttag cgcgctcttt
     4861 catcgtcatc gagttgatga tggcttccat acgcaccagc actttatcgt ccatctgtga
     4921 cttgacgtta tccgggatct gccccatgcc cggcagcttg cccatcagac tagccatgcc
     4981 gcccatattt ttcatctggc gcagctgctc aagaaagtcg ttgagatcga agccgtcacc
     5041 ttttttcagc ttgctggcta atttctctgc ctgcgcgcgg tcaactttgc tttcgatatc
     5101 ttcgatcagc gacagtacgt cgcccatgcc gagaatacgc gacgcgatgc ggtccggatg
     5161 gaacggctcc agcgcctcag ttttctcgcc aacaccgagg aacttgatcg gtttgccagt
     5221 gatgtgacga atagagagcg ccgcaccgcc gcgggcatcg ccgtccactt tggtcaacac
     5281 tacgccggta agcggtaacg cttcattgaa tgcttttgcc gtattggccg catcctgacc
     5341 ggtcatggcg tcaaccacaa acagggtttc aaccgggtta atcgacgcat ggacttgttt
     5401 gatctcgtcc atcatcgctt cgtcaacgtg cagacgacca gcggtatcca ccagcagcac
     5461 gtcgtagaat ttcagtttgg cttctttcag cgccgcgtta acgatatcta ccggcttctg
     5521 accaacatca gaagggaaga aatcaacgcc cacctgctct gccagcgtct caagctgttt
     5581 gattgccgcc gggcgataaa cgtcggcaga aaccaccagc actttcttct tgtgcttctc
     5641 gcgcaggaac ttaccgagtt taccaacgct ggttgtttta ccggcacctt gcaggcccgc
     5701 catcagtacg accgcaggcg gttgcgcagc caggttcagg gtctggttct cttcgcccat
     5761 cgccgcaacc agttcgttac ggactatttt gacgaactcc tgccccggcg tcaggctctt
     5821 attaacttca tgaccaaccg ctttctcttt tacgcgattg ataaactcac gcactaccgg
     5881 cagagctacg tccgcctcca gcagcgccat gcgcacttcg cgcagcgtat cttttacgtt
     5941 gtcttcagtg aggcgtccac ggccactgat attgcgcagc gtgcgcgaca aacgatcggt
     6001 taaattatca aacattgtct ctcgcctggg gtggaaacgg ttggccgcaa tcgcgacaca
     6061 tcatcagtat tttgccgcag tataacatga aggcgtcttt gttgttatgc aacggttgga
     6121 gcagcgttca cctgacgcta tactgcttct ctttcttatt gctcaaactg tcgacatcac
     6181 tatgcccgtt tttgctctgc tcgcgcttgt cgcctactcc gtcagtcttg cgctgattgt
     6241 tcccggtctg ctgcaaaaaa acggcggctg gcggcgcatg gctattattt ctgcggtcat
     6301 tgcgctggtc tgccacgcaa tcgctctgga agcccgcatc ctgcccgacg gtgatagcgg
     6361 acaaaacctc agcctgctga acgttggttc attggtcagt ttgatgatct gtacggtaat
     6421 gaccattgtg gcttctcgca atcgtggctg gctgctgcta cccattgtct atgcctttgc
     6481 gcttatcaac ctggcgctgg caaccttcat gcccaatgaa tacatcaccc atctggaagc
     6541 tacgcctggg atgctggtgc acattggctt atcgctcttt tcctatgcca cgctaattat
     6601 cgccgccctg tacgcgctgc aactggcgtg gattgattac caactgaaga acaagaagct
     6661 ggcgtttaac caggaaatgc cgccattgat gagtatcgag cgtaaaatgt tccacatcac
     6721 gcagattggc gtggtgctgc taacgctcac gctttgcact ggcctgttct acatgcacaa
     6781 cttatttagc atggaaaata tcgacaaggc tgtgctctct atcgtggcgt ggtttgtcta
     6841 tattgtgctg ctgtggggac attatcatga aggatggcgt ggacgccgcg tcgtctggtt
     6901 taacgttgcg ggcgcggtaa ttctgacact ggcctacttc ggcagccgaa ttgtccagca
     6961 gttaatcagc taaacccaga aaaggagttt cccctggaac acatttctac tactacgttg
     7021 atcattattc tgatcatcat ggtggtcatt tcagcctatt tttccgggtc cgaaaccgga
     7081 atgatgaccc tcaaccgcta tcgtctgcga catatggcga aacagggtaa tcgctcggcc
     7141 aaacgcgtcg aaaaattgct gcgtaagcca gaccgcctga taagcctggt gttaatcggc
     7201 aataacctgg tcaatattct tgcctccgcg ctcggcacta ttgttgggat gcgtttgtac
     7261 ggcgatgcgg gcgtggcaat tgcgactggt gtgctgactt ttgtcgtact ggtatttgct
     7321 gaggtattgc cgaaaaccat tgccgcgctg tacccggaaa aagtcgctta tccgagtagt
     7381 tttctgctgg ctccgctgca aattttgatg atgccgctgg tctggttgct gaatgctatc
     7441 acccgtatgc tgatgcgcat gatgggtatc aaaaccgata tcgtggttag cggctctttg
     7501 agcaaagaag agttgcgcac tatcgtgcac gaatcacgct cacaaatttc ccgtcgcaat
     7561 caggatatgc tgctgtcggt gctcgatctg gaaaaaatga ccgttgatga catcatggtg
     7621 ccgcgcagtg aaattatcgg tattgatatc aacgatgact ggaaatcgat tctgcgccaa
     7681 ctctcccact cacctcacgg gcgcatcgtg ctctaccgtg attcgctgga cgacgccatc
     7741 agtatgctgc gagtacgtga agcctggcgg ttgatgtcgg agaaaaaaga gttcaccaaa
     7801 gaaaccatgc tgcgcgccgc ggacgagatc tattttgtgc cggaaggtac gccgctcagc
     7861 acgcagttgg taaagtttca gcgcaacaaa aagaaagtcg gcctggtcgt caacgagtat
     7921 ggagacattc aggggctggt gacggttgaa gatattctgg aagagattgt cggcgatttc
     7981 actacgtcga tgtcgccaac acttgccgaa gaggtcacgc cgcaaaacga cggttcggtg
     8041 attatcgatg gcaccgccaa cgtgcgggaa atcaacaaag cctttaactg gcatctaccg
     8101 gaagatgatg cccgcacggt taatggcgtc attcttgagg cactggaaga gatccctgtc
     8161 gcaggcaccc gcgtgcgtat tggcgagtac gatatcgata ttctcgacgt acaggacaat
     8221 atgattaagc aggtaaaagt ttttcctgtg aaaccgctgc gcgagagtgt ggcggagtaa
     8281 cgaaaacggc ccggcattcg catgcagggc cgtgaattat tacgaaagca gaaattaagc
     8341 ttttgctttc gctacagtaa ccatcgccgc acgaatcgta cgaccattca gcgtataacc
     8401 cttctgcata atgcccagta cgttacctgg cgcaacgtca tcagattcca ccattgcgat
     8461 ggcctgatgc acattcgggt ccagtgggac gttagtttcg gcgatcactt caacgccaaa
     8521 cttacgcaca acatccagca tcgacttcag cgtcagctca atgccttcaa ccatcgcaga
     8581 catatccggg ttagctttat cagccacttc cagcgcacga tccaggctat caatcaccgg
     8641 cagcaattcg ttgatgaatt tctccagcgc gaatttgtgg gctttttcaa tatccagttc
     8701 agtacgacga cgcaggtttt ccatttcggc ttttacacgc aaaatgccgt cacgttcacg
     8761 ggtctgggct tcagccagct gagcttcgag attcgcaatt ttttcatcgc gcggatccac
     8821 ctgctcagca gaagcttctg gctcaactgc ctcaatctct tcgtgctgat ccatgataat
     8881 ttcttccggg gcttgcccct caggcgtttt ctgttcttta ctactcatga atttctccgc
     8941 gtttttttcg cattcatctc gctaacttcg cttattatgg ggatcagttt cagggtttca
     9001 agggaagcac tcacattgtc atcaatcttc gcaacaagga cctcggaaaa atgaataatc
     9061 atttcaagtg tattggcatt gtgggacacc cacggcaccc cactgcactg acaacacatg
     9121 aaatgctcta ccgctggctg tgcacaaaag gttacgaggt catcgttgag caacaaatcg
     9181 ctcacgaact gcaactgaag aatgtgaaaa ctggcacgct cgcggagatt gggcaactag
     9241 ctgatctcgc ggtagtcgtt ggtggcgacg gtaatatgct gggcgcggca cgcacactcg
     9301 cccgttacga tattaaagtt attggaatca accgtggcaa cctgggtttc ctgactgacc
     9361 ttgaccccga taacgcccag caacagttag ccgatgtgct ggaaggccac tacatcagcg
     9421 agaaacgttt tttgctggaa gcgcaagtct gtcagcaaga ttgccagaaa cgcatcagca
     9481 ccgcgataaa tgaagtggtg cttcatccag gcaaagtggc gcatatgatt gagttcgaag
     9541 tgtatatcga cgagatcttt gcgttttctc agcgatctga tggactaatt atttcgacgc
     9601 caacaggctc caccgcctat tccctctctg caggcggtcc tattctgacc ccctctctgg
     9661 atgcgattac cctggtgccc atgttcccgc atacgttgtc agcacgacca ctggtcataa
     9721 acagcagcag cacgatccgt ctgcgttttt cgcatcgccg taacgacctg gaaatcagtt
     9781 gcgacagcca gatagcactg ccgattcagg aaggtgaaga tgtcctgatt cgtcgctgtg
     9841 attaccatct gaatctgatt catccgaaag attacagtta tttcaacaca ttaagcacca
     9901 agctcggctg gtcaaaaaaa ttattctaat tttacgccag cctctttact gtatataaaa
     9961 ccagtttata ctgtacacaa taacagtaat ggtttttcat acaggaaaac gactatgttg
    10021 gcacaactga ccatcagcaa ctttgctatc gttcgtgagc ttgagattga ttttcatagc
    10081 ggcatgaccg taataactgg cgagaccggc gcgggtaaat ctattgcaat agatgccctc
    10141 ggtctttgtc tcggtggtcg cgctgaagcc gacatggtgc gtaccggcgc tgctcgcgct
    10201 gacctgtgcg cccgtttttc tctgaaagat acgccagcgg ctctgcgctg gctggaagaa
    10261 aaccagcttg aagacgggca tgaatgtttg cttcgtcgcg tgatcagcag cgatggtcgc
    10321 tcccgtggtt tcatcaacgg tacagctgtt cctctgtcac aactgcgcga actgggtcag
    10381 ttgctgattc agatccatgg tcagcacgct catcaattac tcaccaaacc tgagcaccaa
    10441 aaattcctgc ttgatggcta tgccaatgaa acctctctac tgcaggaaat gaccgcacgt
    10501 tatcagttgt ggcatcaaag ctgccgtgac ctcgcgcatc atcaacagtt aagtcaggaa
    10561 cgcgccgccc gtgcggaact gctgcaatac caattaaaag aacttaacga atttaatccg
    10621 cagcccggag agtttgaaca aatcgacgaa gagtacaaac gtctggcgaa cagcggtcaa
    10681 ttgctgacca ccagccagaa tgcattggca ttaatggccg acggtgaaga cgcaaacctg
    10741 caaagtcagc tttacacggc taaacaactg gtgagcgaat tgattggcat ggacagcaaa
    10801 ctgtccggcg tacttgatat gctggaagaa gctaccatcc agattgctga agccagcgat
    10861 gaactgcgcc actactgcga tcgtctggat ctcgatccca accgactatt tgaacttgaa
    10921 cagcgcatct caaaacagat ttcgctggca cgtaaacatc acgtcagccc tgaggcattg
    10981 ccacagtatt accagtcgct actggaagaa cagcagcaac tggacgatca ggccgactca
    11041 caagaaacgc ttgcgctggc ggtaacgaaa catcatcagc aggcactgga aatcgcgcgc
    11101 gcattacacc aacaacgcca gcaatatgca gaagaacttg cacagctgat caccgacagt
    11161 atgcatgcgc tctcaatgcc gcatgggcag tttacgatcg atgttaaatt tgacgagcat
    11221 cacctgggcg ctgacggtgc cgatcgtatt gagtttcggg taaccaccaa cccaggtcag
    11281 ccaatgcagc ctattgccaa agtcgcatcc ggtggtgaat tgtcccgcat cgcactggca
    11341 atccaggtca tcacggcgcg taaaatggaa accccggcac tgatttttga tgaagtggat
    11401 gtagggatta gcggtccaac agcggcagtt gtcggcaaac tgctgcgtca actcggcgaa
    11461 tcaactcagg tgatgtgtgt tacccacctg ccacaagtcg cgggatgtgg tcatcaacac
    11521 tattttgtca gcaaagaaac cgatggtgcg atgacagaaa cgcatatgca atccctgaat
    11581 aaaaaagcgc ggttacaaga gctggcgcgc ctgcttggtg gcagtgaagt cacacgtaat
    11641 acactggcga atgcgaaaga actgcttgca gcgtaaactt ttttcctgct tcacggtcag
    11701 agtaaacagc aaaacgccgt aagaccggaa agcaaaaggt tttaaagtga tgaaaggtct
    11761 attatcatcg gcatattaca gatgagccac gtactgctcg ggcccgaaaa ggaatcaaat
    11821 cactatgcgc tgtaaaacgc tgactgctgc agcagcagta ctattgatgt tgaccgcagg
    11881 ctgttccact ctggagcgag tggtttaccg tcctgacatc aaccagggga actatctgac
    11941 cgctaacgac gtatccaaaa tacgtgttgg catgacgcaa caacaagttg cgtacgcatt
    12001 gggtacaccg ctgatgtccg atccatttgg tacgaatacc tggttctatg tcttccgcca
    12061 gcaaccaggt catgaaggtg taactcagca aacgctgacg ctgaccttta acagtagcgg
    12121 tgtgttgacc aatattgata acaaacctgc gctgagtggt aactaataat aaagttgctc
    12181 tcaaagacgt taaaaaaggt gctcaatgag cacctttttt ctgtctgtta tttattcgct
    12241 gatttttctg ctcgttgcct gcgaagctct ttcggatcgg caatgagagg gcgataaatc
    12301 tccacccgat cgccatcatg cacactatcg cttagttttg ccggacggct gtaaatgccg
    12361 actttgtttt tagttaaatc gatatcggta cgcaattcca gcaagccact ggcgcgaata
    12421 gcttcttcaa ccgtcgcgcc ctcctgcagc gtcactcgct gcaggtactg cttctcaggt
    12481 agcgcataag ccacctcaac ggcaatttta cctggcactg taaacctctt tcgcacgaac
    12541 cgtaaaagcc tggaccatat tagccgccag ctctttaaac acgcgaccaa aggcgagttc
    12601 aatcaactta ttggtaaact caaagtcgag atgaaactcg atacgacacg cctcctggct
    12661 cagcggcgta aacttccatc caccaatcaa tttcttgaac ggcccatcca ccagattcat
    12721 aagaatactt tggttactgg tcaactggtt gcgggtagta aacgttttgc tgatcccagc
    12781 cttagagaca tctaccgccg cagtcatctg cccaggagtg gactccagaa tccgacttcc
    12841 ggtacaaccc ggcaaaaact gaggataaga ctgaacgtca ttcactaact gatacatttg
    12901 ctccgcgctg tagggtacca gtgcggtccg gctaatctga ggcataacaa tttccatcaa
    12961 caaaaatcca acaaataata tcatttatcc tgctgtaaaa aaaacgctat cccggcgctg
    13021 ggtaacatcg ggttcatgct aagatagagc cttgtccccc gcaggattga tatggggtgt
    13081 tttcgatttc agattaccga tgattcacga cgcttatgac gaagaaaaaa gcacataaac
    13141 ctggttcagc gaccatcgcg cttaacaagc gcgcccgtca cgaatacttt atcgaagaag
    13201 agttcgaagc gggacttgcc ctgcaaggct gggaagttaa atccctgcgc gcaggaaaag
    13261 ccaatatcag cgacagctac gtccttctgc gtgacggaga ggcatttctg tttggcgcta
    13321 acatcacgcc aatggccgtg gcctccacgc atgtggtgtg cgatcctacc cgtacccgca
    13381 agttacttct caaccagcgc gaactggact cattgtacgg tcgcgtcaat cgagaaggct
    13441 ataccgtagt ggcgctctcc ctgtactgga aaaatgcctg gtgcaaagtg aaaatcggcg
    13501 tcgccaaagg taagaaacag cacgataaac gttcagatat caaagagcgc gaatggcagg
    13561 tggataaagc acgtatcatg aaaaacgccc accgttaaac ctgcactcca attattgacc
    13621 agttcctcac cgcgcctccc tctccggcgg cgcgaatgaa catcttattg gctatcacat
    13681 ccgacacaaa tgttgccatc ccattgctta atcgaataaa aatcaggcta catgggtgct
    13741 aaatctttaa cgataacgcc attgaggctg gtcatggcgc tcataaatct ggtatactta
    13801 cctttacaca ttggggctga ttctggattc gacgggattt gcgaaaccca aggtgcatgc
    13861 cgaggggcgg ttggcctcgt aaaaagccgc aaaaaatagt cgcaaacgac gaaaactacg
    13921 ctttagcagc ttaataacct gcttagagcc ctctctccct agcctccgct cttaggacgg
    13981 ggatcaagag aggtcaaacc caaaagagat cgcgtggaag ccctgcctgg ggttgaagcg
    14041 ttaaaactta atcaggctag tttgttagtg gcgtgtccgt ccgcagctgg caagcgaatg
    14101 taaagactga ctaagcatgt agtaccgagg atgtaggaat ttcggacgcg ggttcaactc
    14161 ccgccagctc caccaatcat gattggacgg tgtaaggaca acaccaacaa aaacaggaag
    14221 ttagcagtct cagcaggaca ccgatcagac ggtgaggaga caaaaaagga tacgcaaagg
    14281 agccgcggct ctcgagtgac acaaaagccc gcttatgcgg gctttttgtt tttcccttaa
    14341 gttcctagcc gcttatctat aactatggaa aaatgttaac cctgactgta tgttaacaaa
    14401 gggatgtata tgtcggtttt tcataactgg ctgcttgata tcgcaagcgg gaattacttt
    14461 atctacatca aacgtctttc tgcaaacgac acaggcgcaa caggtggcca tcaggtcgga
    14521 ctttatatcc cctcaaatat cgttgaaaag ctttttccat ctatcaatca tactcgcgaa
    14581 ctgaaccctt cagtcttcct tactgcgcat gtatcatccc atgattgccc tgatacccaa
    14641 gcacgcgcaa tttattacaa caaccgttat tttggtaaga cccgaaacga aaaaagaatt
    14701 acgcgctggg ggagaggaag tccattacag aaccctgaaa atacaggagc cctcacaatt
    14761 cttgctttca ggttaaacga acagaacact gactgttccg aggtagatat atgggtctgc
    14821 gtcaatcccg atgaagagga tatcatcgag tctgctattg gcgaaatcat acctggaacc
    14881 ctaatttccg gccctgccgg acaaattttg ggcggattgt ctcttcagca aactccagta
    14941 aatcataaat atgttattcc tgaagactgg aagaagcgtt ttccttctgg aaacgaaatt
    15001 attcaatatg ctgctggcca ttatgctaaa aactccaagg atccagatga gcaactgatt
    15061 gaccgtcggc gtgtcgagta tgatattttt ctactcgtcg aagaattaca tgttcttgat
    15121 attattaaga aaggattcga ttctgtagat gagtttattg cattagccaa ctctgtcagt
    15181 aatcgacgta aatcaagggc aggtaaatca cttgaacttc acctagagaa gctttttatc
    15241 gagcacggac tacggcattt ctccactcag gcagttactg aaggtaataa aaaaccagat
    15301 ttcctgtttc cttcagcaga ggcatatcat aacgttgaat ttcctgtaga aaacttacgt
    15361 atgctggcag taaagaccac ctgcaaagat cgctggcgtc agatactgaa tgaagcagat
    15421 aaaatccatc aggtacattt atttacgctg caagaaggtg tttcttcagc acaataccga
    15481 gaaatgaaag atgcgggtgt cagactcgtt gtaccatcaa ctttacataa aaaataccca
    15541 gaagcagtta gagaagaatt aataacgctc ggagcattca ttactgagct gatagaactt
    15601 tacgctgaac tatcataggc tgactcccgg cttaaaaggc cgggaggtgt tctcaaggct
    15661 gcccagtctt accagcatca gcagaaacag ctttgaggat atagggttcc agaagtctgg
    15721 caacggcttc aaatactggc accacaacgg agttaccgaa ctgccgatat gactgagtat
    15781 ctgaaaccgg aatacggaat ggtttccctc caggtttttc aaaccccata aggcgtgcgc
    15841 actctcgggg agtcagcctg cgtggtcgac gagcctggtt actctcattc ataaagtcag
    15901 cctctcccgt tgccatatcc caaccacgat caataagaat ttctgatccg tctttgtgat
    15961 atctggcaga aagtgtgcgt gcaatgcttt ccttattctc aggattgacc aacccaaagc
    16021 caaaaccatt tcccttggct gcatgctttt tggcgtagtt ataaaggtac tcccatagtt
    16081 ttggcgtaag tatatattta ctgtcgacta caggctccag caattcacca aatgatgggc
    16141 ggtgttccgg ataaaaacga ctgatatcac gcaaggtaaa ccccttgtga atattcagat
    16201 ctcgtctaaa tccgaccaga acaatgcgtt cacgatgctg aggcaaaaaa tgcttcccat
    16261 cgataatctt tggatcgttt tttcccattt ctgcagcatc ggcaacttcg tagcccagct
    16321 cgtcaagggt ctccataatg actttgaaag ttttaccctt atcatggctc ttcagatttt
    16381 tgacattttc cagcacaaaa attgccggtt tttttgctcg tataatacgt gccacgtcaa
    16441 aaaaaagtgt tccttgtgct tcacattcaa aaccatgcgc acgaccaagt gagtttttct
    16501 tactaacacc agcaaggcta aatggctggc acgggaaccc cgcaagaagc acatcatgat
    16561 ccggcacatg ctcatcaata tatgcataag catccgtttc caatacatcg gttttatcac
    16621 tcagcgtgac ttcccgaata tcgagattga atttatgcac ctgttcatcg ttaaaccagt
    16681 tggccttgta tgtacgcaca gcatctttat tccattcact ggtaaaaaca cactggcctc
    16741 caatggcctc aaaacctttc cgtatccctc caattccagc aaataagtca atgaagcgga
    16801 aagcatattc cggatggttt gcaggtggtt ctggtagcat cttacgcaga agagactctt
    16861 ctactgaagt caacgatttt ggtaaacact tgccattaat ccagcggttg atggtttcac
    16921 ggctccactc attttttccg acttttctca gtaattcagc cacatacttc tgatcataga
    16981 tttccagcac tttctcgata agctttttat cattttcctg tcgcagcttt tcttccgcct
    17041 cggcttcctt cagcagatgc tgtgccaaca cttcaaattc agacataatt cctccaaggg
    17101 gtctaatggg tgaaactcta tcactcattc aacccagaag gaaatgtttt atctggatat
    17161 ttaaacagtg actacaacgt aatctagcac tggtgatgct ttgttaggca tagagaatca
    17221 ttctatatac gactaatgac agaaaaacag cagacaagta gtttgttcat aaattaacgc
    17281 atactacgtg cctacggttt tcgagaccgg tccaatcatc aaacgaaaca taaaattagc
    17341 tcacattatg aggaaaagta tcttttttgt actatgtaaa ttcaaaggct tagcctcatt
    17401 tctccgatgt ttttctcaac actactggtt gtgagccctt gcaatgttca ttaatatacg
    17461 tctcacaaat aattcataga tattgcaaaa tggatattac tgagtttcct tctggagtaa
    17521 ttgaacacct tggctggtat gtataccgat tgattgatcc gagggacgga agcaccttct
    17581 atgtagggaa aggcaaaggt aaccgcgtat ttgcccatat gcgcggtgaa gtggcagcga
    17641 ctgatgatga cgagttactg agcaacaagc taaagcaaat tagagaaata aggttagcag
    17701 gacttgaggt tatccatgtc atccatcgac acggaatgac tgatgaaaag acggcgtacg
    17761 aagttgaagc agcacttatt gatgcctacc ctgggttaac gaatatcatg aatggtgctg
    17821 gcagcaatga attcggcgcc gcgcatgtca aagagttgat agcaacatat caacccgaaa
    17881 ccataacatt tcatcataaa gcattaatga tttccgttaa cagaagtgca aaggattcag
    17941 agctttatga tgcggttcga tttagctggc gcattaatgt ctctcgcgcc agccaagcag
    18001 aagtcattct tgctactgta agggggatcg ttcgaggggt tttcattgct gataaatggc
    18061 tcaaatcaac acgtgaaaat ttccctacga tgaaatactg ggacgaggat ccggactttg
    18121 aggcaacaca aagttctcgc tatggttttg aaggtcgaga agccccacct gaaatagcaa
    18181 atctttatct tggaaaaaaa ataccagatg aattaagaaa aaaaggagct atgtccccgg
    18241 tccgttactc acctaatttt tgagtcttta agtgataagc ataaaccgca gcacgat
//
LOCUS       DAPHKZ010000089        18099 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.089, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000089 DAPHKZ010000000
VERSION     DAPHKZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18099
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.089"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            45..1064
                     /locus_tag="RH288_003182"
     CDS             45..1064
                     /locus_tag="RH288_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV4032214.1"
                     /translation="MNNEQMLIKCKDPRKCRFYAEYLNHKYPNEFPQFAPDNPQNCIR
                     NVNSFLKEKYYKASNNSFGVFGSTAEEALSKEINELEIIAGQAILPEESFLWLKTDEL
                     ATFFTWTTIYLSKEDHTNFPEINHNSSGIKNGIEVRKRRTVTDETLNTYKKSNLPDNP
                     SSHNERIKVIISYFDSCHSLINKNAKSIYLEELRQTWLKNKSACQKFKWLLPDDDEMC
                     QWFWTRLKQKQDETHPVHNPVTRWFIPSSTKEYYLASLVAFALWKEAPDTIELFRTRI
                     NHAWHQKKQKDKYRSDGKKAINIHIRSNAKEMLDELRTVYGLRTGEFFEMLITEKYLE
                     HKRRK"
     gene            1174..2046
                     /locus_tag="RH288_003183"
     CDS             1174..2046
                     /locus_tag="RH288_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDV4032215.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTSHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLSGHGHSMIITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRAQAREQFTGAVDRIFDTAESVCIASVARTVLRAVRDS
                     VVSVARAVWNWIFF"
     gene            2418..5264
                     /gene="ag43"
                     /locus_tag="RH288_003184"
     CDS             2418..5264
                     /gene="ag43"
                     /locus_tag="RH288_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HDV4032216.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLTA
                     VTSVQALAADTIVQAGETVNDGTLTNHDNQIVFGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGIANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     GGIATGTVINEKGWQAVKSGAMATDTVVNTGAEGGPDAENGDTGQFVRGNAVRTTINE
                     NGRQIVAAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASGTVVNSDGWQ
                     IIKEGGLADFTTVNQKGKLQVNAGGTATHVTLKQGGALVTSTAATVLGSNRLGNFTVE
                     NGKADGVVLESGGRLDVLEGHSAQKTRVDDGGTLAVSAGGKATGVTMTSGGALIADSG
                     ATVEGTNASGKFSIDGTSGQASGLLLENGGSFTVNAGGLASNTTVGHRGTLMLAAGGS
                     LSGRTQLSKGASMVLNGDVVSTGDIVNAGEIYFDNQTTPDAILSRAVAKGNAPVTFHK
                     LTTSNLTGQGGTINMRVRLDGSNTSDQLVINGGQATGKTWLAFTNVGNSNLGVATTGQ
                     GIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTS
                     MLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSY
                     GFVRLESDLLRTEVAGMSVTAGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNL
                     VHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQL
                     QYTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMSFGEGTSSRDTLRDSAK
                     HSVSELPVNWWVQPSVIRTFSSRGDMSMGTAEAGSNMTFSPSQNGTSLDLQAGLEARV
                     RENITLGVQAGYAHSVSGNSAEGYNGQATLNVTF"
     gene            5591..6409
                     /locus_tag="RH288_003185"
     CDS             5591..6409
                     /locus_tag="RH288_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV4032217.1"
                     /translation="MRLASRFGYANQIRRDRPLTREELMQVVPSVFGEEKHTSRSENY
                     TWIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRDGEINGQHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGDVVEKVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTAADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSARGKRIHTRAIHSIDTDIKLNRALWVMAETLLKSMR"
     gene            6500..6985
                     /locus_tag="RH288_003186"
     CDS             6500..6985
                     /locus_tag="RH288_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV4032218.1"
                     /translation="MTTVLHNSTTPSVSVTAVSENNPPQLVATLVPDEQRISFWPQHF
                     GLIPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFSA
                     MNGNRAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECNAIMCII
                     D"
     gene            7000..7476
                     /locus_tag="RH288_003187"
     CDS             7000..7476
                     /locus_tag="RH288_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HDV4032219.1"
                     /translation="MQQLSFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTHAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VILAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEHGLL"
     gene            7563..7784
                     /locus_tag="RH288_003188"
     CDS             7563..7784
                     /locus_tag="RH288_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HDV4032220.1"
                     /translation="MKIIPRGEAMRIHRQHPASRLFPFCTGKYRWHGSTDTYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            7864..8232
                     /locus_tag="RH288_003189"
     CDS             7864..8232
                     /locus_tag="RH288_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDV4032221.1"
                     /translation="MSDTFSGTTHPDDNHDRPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFSDADSYHLDQAFPLLMKQLELMFTSGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCGYVYMAVYPTPETKK"
     gene            8322..8699
                     /gene="cbtA"
                     /locus_tag="RH288_003190"
     CDS             8322..8699
                     /gene="cbtA"
                     /locus_tag="RH288_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
                     /protein_id="HDV4032222.1"
                     /translation="MKTLPVLPGQAASSRPSPVEIWQTLLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPEFSACTRSQLINSIDILRARRATG
                     LMTRDNYRTVNNITLGKYQEAKR"
     gene            8696..9184
                     /locus_tag="RH288_003191"
                     /pseudo
     CDS             8696..9184
                     /locus_tag="RH288_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708774.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9204..9401
                     /locus_tag="RH288_003192"
     CDS             9204..9401
                     /locus_tag="RH288_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032223.1"
                     /translation="MKLLTTETALDILIAWLQDNIDCESEIIFDNDEDKTDSAALLPC
                     IEQARQDVRTLRHLQFQHLNR"
     gene            9498..10340
                     /locus_tag="RH288_003193"
     CDS             9498..10340
                     /locus_tag="RH288_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HDV4032224.1"
                     /translation="MSGITIARPEVVNGHTDVICSTSIRHILAVRKSTLLQIDTLIRQ
                     LAEISAMTESIGGKTAPDWAMKQDFRCGCWLMEKPETAMKAITRNLDREIWRDLMQRS
                     GMLSLMDAQARDTWYRSLEHDNFPEISEANILSTFEQLHQNKDEVFERGVINVFRGLN
                     WNYKTNCPCKFGSKIIVNNLVRWDRWGFHLITGQQTDRLVDLERMLHLFSGKPIPDNR
                     ENITIRLDGHIQSVQGKERYEDEMFIIKYFKKGSAHITFKRLELIDRINDIIARYFPS
                     VLSA"
     gene            11089..12627
                     /gene="cadC"
                     /locus_tag="RH288_003194"
     CDS             11089..12627
                     /gene="cadC"
                     /locus_tag="RH288_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylation/transport transcriptional
                     activator CadC"
                     /protein_id="HDV4032225.1"
                     /translation="MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHS
                     GEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMV
                     PVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
                     VWFFFLLSLGICVALVAFSSLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLS
                     YAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSI
                     KLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQRMQETLQKILPHRG
                     ALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPL
                     DEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSW
                     LNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKF
                     LASE"
     gene            12992..14326
                     /gene="cadB"
                     /locus_tag="RH288_003195"
     CDS             12992..14326
                     /gene="cadB"
                     /locus_tag="RH288_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HDV4032226.1"
                     /translation="MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWI
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
                     TAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALM
                     ILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVL
                     GCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH"
     gene            14406..16553
                     /gene="cadA"
                     /locus_tag="RH288_003196"
     CDS             14406..16553
                     /gene="cadA"
                     /locus_tag="RH288_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HDV4032227.1"
                     /translation="MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLK
                     LIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISF
                     FEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTN
                     GTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWV
                     PYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWF
                     FDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFG
                     IPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRV
                     KNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAF
                     QKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKEESKK"
     gene            16612..18069
                     /gene="dtpC"
                     /locus_tag="RH288_003197"
     CDS             16612..18069
                     /gene="dtpC"
                     /locus_tag="RH288_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpC"
                     /protein_id="HDV4032228.1"
                     /translation="MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDN
                     HAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL
                     YLAPAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVM
                     LCLAPVFFTLLLENDWSGYLLAIVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTL
                     FWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVMLAGVVLAWLASPESR
                     GNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMISGLALMGFAELFID
                     PVAIAQITRLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQ
                     MGEWTLACVAIIVVLAFATRFLFSTPTNMIQESND"
BASE COUNT         4565 a         4467 c         4504 g         4563 t
ORIGIN      
        1 attgagacga ttttgttata agagaggcgc catggagtga gataatgaat aacgaacaga
       61 tgcttatcaa atgcaaagat ccccgtaaat gtcggtttta tgccgaatat ctgaatcaca
      121 aataccccaa tgaattccct cagtttgcgc ctgacaaccc acaaaactgt atcagaaatg
      181 ttaattcgtt tttaaaagaa aagtattata aagcttcaaa caattctttt ggtgtttttg
      241 gttcgactgc agaagaagct ctcagcaaag aaattaatga acttgaaatt attgcagggc
      301 aggcaatact gcctgaagag agttttctct ggttgaaaac tgacgaactt gcgactttct
      361 ttacctggac tactatttat ctgtcgaagg aagaccatac aaatttcccg gaaataaacc
      421 ataattcatc agggataaaa aacggaattg aagtcagaaa aagacgaaca gttaccgatg
      481 aaacgttaaa tacttacaaa aaaagtaacc ttccggataa tccatcatcc cataacgaac
      541 gaataaaagt aatcatttca tattttgatt cctgtcattc tttaattaat aaaaatgcaa
      601 aaagcatata cctcgaggaa ctcaggcaga cgtggcttaa aaataaaagc gcttgtcaaa
      661 agtttaagtg gctccttcct gacgatgatg aaatgtgtca gtggttctgg acaagactga
      721 aacaaaaaca ggatgaaaca catccggtac ataacccggt gacccggtgg ttcataccat
      781 cttcaacgaa agaatattat cttgcctctc tcgtcgcctt tgctttatgg aaagaggcac
      841 ctgataccat tgaactgttc agaacacgca taaatcatgc ctggcatcaa aaaaaacaaa
      901 aagacaaata tcggagtgat ggtaaaaagg ctattaatat acatataaga agcaatgcga
      961 aagaaatgct tgatgaactc agaactgttt acggtctgag aacaggagag ttttttgaaa
     1021 tgctgattac agaaaaatat cttgaacaca agcgaaggaa gtaattcatt acctgttaca
     1081 ttctaaataa tctcagacag atattatctc cgtgaatccc ccgccacctt tccggtgcgc
     1141 ggggttttgt cttttttcac cgggaataca tgtatgaatc cgtctgatgc cattgaggca
     1201 attgaaaaac cgctctcctc cctgccttac tcactttccc gtcacatcct ggaacatctg
     1261 cgcaaactca ccagtcacga acccgtgatt ggcattatgg gtaaaagcgg ggccggtaaa
     1321 tcctcactct gtaatgcact gtttcagggg gaggtcaccc cggtcagtga tgttcacgcc
     1381 ggcacccggg aagtgcggcg cttccgtctg agtggccacg gtcacagcat gattatcact
     1441 gacctgcccg gggtgggcga gagccgggac agggatgcag agtatgaagc cctgtaccgt
     1501 gacattctgc ctgaacttga cctggtactg tggctgatta aagccgatga ccgtgccctg
     1561 tctgtggatg agtatttctg gcgacacatc ctgcaccggg gacatcagca ggtgctgttt
     1621 gtggtgacgc aggccgacaa aacggagccc tgccatgaat gggatatggc cggcattcag
     1681 ccttctcccg cacaggcaca gaatattcgc gaaaaaacgg aggcggtatt ccgtctgttc
     1741 cggcccgtac atccggttgt tgccgtatcg gcccgcaccg gctgggaact ggatacgctg
     1801 gtcagtgcgc tcatgacagc acttcccgac catgccgcca gtcccctgat gacccgcctg
     1861 caggacgagc tgcgcacgga atctgtccgc gctcaggccc gtgaacaatt taccggtgcg
     1921 gtggaccgaa tatttgacac ggcggagagc gtctgtattg cctctgttgc acgcacggtt
     1981 ctgcgtgccg tccgtgactc ggtggtctct gttgcccgcg ctgtatggaa ctggattttc
     2041 ttctgaacag tctgccaggg gaaatgcctg attacattgc gttaaccaac tgaaaacatg
     2101 atacaccccc ctcatatcca cctctttctc ttgcgtgact gccttgctgt taatagaata
     2161 aaacgatcga taaaacaggt atcgatcgtt gctatcgatc gtttatagtg gttaatggcc
     2221 tgcgaaaagg cagttgaatc tcttcatcat gcagaacgga attgcacaca acggactgat
     2281 acttctctgg cggatgagag aggggaagca tttatgtccg ggaaaaaaca ctttatctga
     2341 ccatgctgtt ttgtacctgc cggtatccac atttgtgggt accggctttt ttattcaccc
     2401 tctgtaagga aaagctgatg aaacgacatc tgaacaccag ctacaggctg gtatggaatc
     2461 acattacggg cacccttgtg gtggcttccg aactggcccg ctcacgggga aaacgcgccg
     2521 gtgtggcggt tgcactgtct cttactgctg tcacgtcagt ccaggcgctg gctgctgaca
     2581 cgattgtaca ggcgggtgaa accgtgaacg acggaacact gacaaatcat gacaaccaga
     2641 ttgtcttcgg tacggccaac ggaatgacca tcagtaccgg tctggagtat gggccggata
     2701 acgaggccaa taccggcgga caatggatac aaaatggcgg tatcgccaac aacactactg
     2761 tcaccggtgg tggtcttcag agagtgaatg ccggaggaag cgtttcagac acggttatca
     2821 gtgccggagg cggacagagc cttcaggggc aggcagtgaa caccactctg aacggcggtg
     2881 agcagtgggt acatgaaggc gggattgcaa cgggtaccgt cattaatgag aagggctggc
     2941 aggccgtcaa atccggcgca atggcaaccg acacggttgt gaataccggc gcggaagggg
     3001 gaccggatgc agaaaatggt gataccgggc agtttgttcg cggaaatgcc gtacgtacca
     3061 ctatcaatga aaatggtcgt cagattgtgg ctgctgaagg aacagcaaat accactgtgg
     3121 tttatgccgg cggcgaccag actgtacatg gtcacgcact ggatactacg ctgaatgggg
     3181 ggtaccagta tgtgcacaac ggcggtacgg cgtctggcac tgttgtaaac agtgacggct
     3241 ggcagattat caaggaaggt ggtctggcgg atttcaccac cgttaaccag aaaggcaaac
     3301 tgcaggtgaa cgccggtggt accgccacac atgtcaccct gaaacagggt ggagcactgg
     3361 tcaccagtac tgcggcaacg gttcttggca gcaaccgtct gggcaatttc acggtggaaa
     3421 acggtaaggc tgacggcgtt gttctggagt ccggcggtcg cctggatgta ctggaaggcc
     3481 attcagcgca gaaaacacgg gtggatgacg gcggaaccct ggcagtgtct gccggtggta
     3541 aggcaacagg tgtcaccatg acatccggtg gtgccctgat tgcagacagt ggtgccactg
     3601 ttgaggggac caatgccagc ggtaagttca gtattgatgg cacatccggt caggccagcg
     3661 gcctgctgct ggaaaatggc ggcagcttta cggttaatgc cggaggactg gccagcaaca
     3721 ccactgtcgg acatcgtgga acactgatgc tggctgccgg gggaagtctg agtggcagaa
     3781 cacagctcag taaaggcgcc agcatggtac tgaatggtga tgtggtcagt accggcgata
     3841 ttgttaacgc aggggagatt tactttgaca atcagacaac accggatgcc atactgagcc
     3901 gtgctgttgc aaaaggcaac gccccggtaa cgttccataa actgacaacc agtaacctca
     3961 ccggtcaggg tggcaccatc aatatgcgtg ttcgccttga tggcagcaat acctctgacc
     4021 agctggtgat taatggtggt caggcaaccg gcaaaacctg gcttgcgttt acaaatgtcg
     4081 gaaacagcaa cctcggggtg gcaaccaccg gacagggtat ccgggttgtg gatgcacaga
     4141 atggcgccac cacagaagaa ggtgcgtttg ccctgagtcg cccgcttcag gccggcgcct
     4201 ttaactacac cctgaaccgt gacagcgatg aagactggta cctgcgcagt gaaaatgctt
     4261 atcgtgctga agtccccctg tatacatcca tgctgacaca ggcaatggac tatgaccgga
     4321 ttctggcagg ctcccgcagc catcagaccg gtgtaaacgg tgaaaataac agcgtccgtc
     4381 tcagcattca gggcggtcat ctcggtcacg ataacaacgg cggtattgcc cgtggagcca
     4441 cgccggaaag cagcggcagc tatggcttcg tccgtctgga gagtgacctg ctgagaacag
     4501 aggttgccgg tatgtctgtg accgcagggg tatatggtgc tgctggccat tcttccgttg
     4561 atgttaagga tgatgacggc tcccgcgccg gcacggtccg ggatgatgcc ggcagcctgg
     4621 gcggatacct gaatctggta cacacgtcct ccggcctgtg ggctgacatt gtggcacagg
     4681 gaacccgcca cagcatgaaa gcatcatcgg acaataacga cttccgcgcc cggggctggg
     4741 gctggctggg ctcactggaa accggtctgc ccttcagtat cactgacaac ctgatgctgg
     4801 aaccacaact gcagtatacc tggcagggac tctccctgga tgacggccag gataacgccg
     4861 gttatgtgaa gttcgggcat ggcagtgcac aacatgtgcg tgccggtttc cgtctgggca
     4921 gccacaacga tatgagcttt ggtgaaggca cctcatcccg tgacaccctg cgcgacagtg
     4981 caaaacacag tgtgagtgaa ctgccggtga actggtgggt acagccttct gttatccgca
     5041 ccttcagctc ccggggtgac atgagcatgg gtacagctga agccggcagt aacatgacgt
     5101 tctcaccgtc acagaatggc acgtcactgg acctgcaggc cggactggaa gcccgtgtcc
     5161 gggaaaatat cactctgggc gttcaggccg gttatgccca cagtgtcagc ggcaacagcg
     5221 ctgaaggcta taacggtcag gccacgctga atgtgacttt ctgataatca ggtcactccc
     5281 cttcaggccc cggtcataat gaccggggct ttttactttc agggagcaac agatatgccg
     5341 ggttgtacat cacgtttatt gccgaaggct cttttgctgc caaatggcat ctgaatcgtt
     5401 cacaatttgg ccggttattg cccgatcccg atggggttat tgggtgatct ccttccataa
     5461 aaatacgcag ctcgccagtg aagggcttct cagacaataa acgtcattca tttcgtccat
     5521 caggccgcgt cttctccggg agacgcggct ttttcattta taccgctaac tcattcataa
     5581 ggaataaatc atgcgattag ccagtcgttt tggttatgcg aaccagatac gccgtgaccg
     5641 ccccttaacc cgtgaagaac tgatgcaggt cgtccccagc gtattcgggg aagagaaaca
     5701 cacatccaga agcgagaact atacctggat ccccaccatc accgtgctgg aaagcctgca
     5761 acgggaaggc ttccagccat tcttcgcctg ccagacccgc gtgcgcgacc cgggccgccg
     5821 gggatacacc aaacacatgc tgcgtctgcg ccgtgacggg gagataaacg gacaacatgt
     5881 ccctgaaatc atcctgctga actcccatga cggtacctcc agctaccaga tgctgccggg
     5941 ttacttcagg ttcgtctgcc agaacggatg cgtctgtggt cagtctctgg gggaagtgcg
     6001 tgttccacac cggggagacg tagtggagaa agttatcgaa ggggcttacg aggtggtggg
     6061 ggtttttgac cggattgagg agaagcgtga tgccatgcag tcgctggtcc tgccgccacc
     6121 ggcacgccag gcgctggcac aggcggcact gacttaccgt tatggtgacg aacatcagcc
     6181 cgtcaccgct gctgacattc tgacaccgcg acgccgggag gattacggta aggacctgtg
     6241 gagtgcttat cagaccatcc aggagaatat gctgaaaggc gggatttccg gtcgcagtgc
     6301 cagaggaaaa cgtatccata cccgtgccat tcacagcatc gacacggaca ttaagctcaa
     6361 tcgcgcattg tgggtgatgg cagaaacact gctgaagagt atgcgctgat gccttttccc
     6421 tgaaagcgca gttctgactc atgtccgtcc ctgccccgcg acttcttcca ttcatttact
     6481 ttttataagg aataatctca tgacaaccgt tttgcataat tccaccacac cttctgtttc
     6541 cgtaaccgct gtatcagaga ataacccgcc tcaactggtt gccaccctcg tccctgatga
     6601 acagcgcatc agcttctggc cgcagcattt tggcctcatt ccacagtggg tgaccctgga
     6661 gccccgtgtc ttcggctgga tggaccgtct gtgcgaagac tactgcggtg gtatctggaa
     6721 tctgtacacc ctgaacaacg gcggggcatt tatggcaccc gaaccggatg acgatgatga
     6781 cgaaacatgg gtactgttca gtgccatgaa cggtaaccgc gctgaaatga gcccggaagc
     6841 cgccggcatt gctgcctgtc tgatgacgta cagccatcat gcctgtcgta cggagtgtta
     6901 tgccatgacg gtccattatt accggctgcg ggattacgcc ctgcagcatc cggaatgcaa
     6961 cgccattatg tgcatcattg actgaaaggg gccggaacaa tgcaacagct ttcctttctg
     7021 cccggagaga tgacgcccgg cgagcgcagc ctcattcagc gggccctgaa aaccctggac
     7081 cgccatcttc atgaacccgg cgtggccttc acctccacgc atgcggcacg ggagtggctg
     7141 attctgaaca tggcgggact ggagcgggaa gagttccggg tgctgtatct gaacaaccag
     7201 aatcagctga ttgccggtga aaccctcttc accggcacca tcaaccgcac ggaagtccat
     7261 ccccgggaag tgattaaacg tgccctgtac cacaatgccg ccgccgtgat actggcacac
     7321 aaccacccgt ccggtgaagt cacacccagc aaggcagacc gccttatcac ggaacgtctg
     7381 gtacaggcac tgggcctggt ggatatccgg gtgccggacc atctgatagt cggtggcagc
     7441 caggttttct cctttgcgga acacggtctg ctttaacccg tcaccgtcac aatcaccttc
     7501 atatcacttc agtttctctt tctcagctgt ttcttacttt cacattcagg aggactattc
     7561 tcatgaaaat catcccccgc ggtgaagcca tgcgtattca ccgtcagcat cctgcatccc
     7621 gtctttttcc gttctgtacc ggtaaatacc gctggcacgg tagcacggat acatataccg
     7681 gccgtgaagt gcaggatatt cccggtgtgc tggctgtgtt tgcagaacgc cgtaaggaca
     7741 gttttggtcc gtatgtccgg ctgatgagcg tcaccctgaa ctgagtccgg aagggcattc
     7801 agaagagcag aattatcgcc accaccggac cattcttaac caattttctg tgaggatttt
     7861 attgtgtcag acacattctc cgggacaacg catcccgatg acaatcacga ccgcccctgg
     7921 tgggggctgc cctgtaccgt gacaccttgt tttggcgccc gtctggtgca ggagggcaac
     7981 cggttgcatt accttgccga ccgcgccggt atcagaggcc ggttcagcga cgcggattcg
     8041 taccacctgg accaggcctt tccgctgctg atgaaacaac tggaactcat gttcaccagc
     8101 ggtgaactga atccccgcca tcagcatacc gtcacgctgt atgcaaaagg gctgacctgc
     8161 gaagccgata ccctcggcag ttgtggctac gtttatatgg ctgtttatcc gacgcccgaa
     8221 acgaaaaagt aactctccag aataaccttc tgctccggcc tggtgctttc accacgccac
     8281 ttttccattt ttcatctctg catttcagga aaatcttcag tatgaaaaca ttacctgtat
     8341 tacccgggca ggcggccagt tcacgcccgt ctccggttga aatctggcag acactgctca
     8401 cccgactgct ggatcagcac tacggcctta cgctgaatga cacaccgttc gctgatgaac
     8461 gtgtgattga gcagcatatt gaggcaggca tttcactgtg cgatgcggtg aactttctcg
     8521 ttgaaaaata cgcactggtg cgtaccgacc agccggaatt cagtgcctgt acccgctctc
     8581 agttaataaa cagcatcgat atcctccggg ctcgccgggc gactggcctg atgacccgcg
     8641 acaattaccg aacggtaaat aacattaccc tgggtaagta tcaggaggcg aaacgatgaa
     8701 actggccctg acgctggaag ctgacagcgt taacgtgcag gcactgaaca tggggcgcat
     8761 tgtcgttgac gtcgatggtg ttaatctcac tgaactgatt aataacatcg ctgaaaacgg
     8821 ttattcactc cgtgtggtgg aggaattcga ccaacagtca acctgaacac ctccgccatt
     8881 tgcaaccctt gccggcatac gctgcagtac cgcacatatc acggaaacgg acaacgcctg
     8941 gttgtactcg ctgtcacacc agaccagtga cgttggtgaa tcagaatgga ttcatttcac
     9001 aggtagcggc tatctgttac gtaccgatgc gtggtcatac ccggttctgc ggcttaagcg
     9061 cctgggcctg tcaaaaacgt tccgtcgtct ggttgtcaca ctcacccggc gttatggcgt
     9121 cagtctcatt catctggacg ccagcgcaga atgtctgccg gggttcccca ctttcgactg
     9181 gtaatcagga caaaagacac tggatgaaat tattaaccac agaaacggcg ctggatattc
     9241 tgattgcgtg gctgcaggac aatattgact gcgaatcgga aattatcttt gacaacgatg
     9301 aggataaaac ggattcggca gcactgttgc cctgtatcga acaggcgcga caggatgtcc
     9361 gaactctgcg ccatctgcag tttcagcacc tgaaccggtg agtttcactc attatctttc
     9421 tcaccacact tcattccccc gacgccagcc tgaatacggc tggcgttttc atttataaac
     9481 agaaaggaaa accgattatg tcaggcatca caatcgcccg tccggaagtg gtcaacgggc
     9541 atacggacgt tatctgctca accagtatcc gccacattct ggctgtacga aagagcacac
     9601 tgctgcaaat cgacacactt atccggcaac tggctgaaat atcagcaatg acagaaagta
     9661 ttggaggtaa aactgctccg gactgggcca tgaaacagga ttttcgctgc ggttgctggc
     9721 tgatggagaa acctgaaacg gcaatgaaag ccatcacccg caaccttgac cgtgaaatct
     9781 ggcgtgacct gatgcaacgt tcagggatgc tttccttaat ggatgcacag gcccgtgata
     9841 catggtaccg gtcactggag cacgataatt ttccggaaat cagtgaagcg aacattctga
     9901 gcacatttga acaactacac cagaataagg atgaggtgtt tgagcgaggg gtgatcaacg
     9961 tcttcagggg actgaactgg aattacaaaa ccaattgccc ctgcaaattt ggcagtaaaa
    10021 ttatcgtcaa caacctagtg aggtgggacc ggtgggggtt tcatcttatc accgggcaac
    10081 agaccgaccg actcgtcgac ctggaaagaa tgctacatct gttcagcggc aaaccgatcc
    10141 ccgacaaccg ggaaaacatc actattcgtc tggatggtca catccagtcc gttcagggta
    10201 aagagcgcta tgaagacgag atgttcatca ttaaatactt taagaaggga tctgcacaca
    10261 tcactttcaa aaggctggaa ctgattgaca gaattaacga tataatagcc aggtactttc
    10321 cttctgtgct ctcagcctga tcccgagtgt gattcccttt cgatattaaa agggactgcg
    10381 ggtataattg agggtacatt tttaatcaaa ccaaataaat tatattaata tcaatatgat
    10441 aaaagaaatt ttcgattccg agtccggcac caaattcata taaacggacc tccacggagg
    10501 tccgtttttc gtttcaggac gccacgattt aagcgttctg cctccaaatc aattctaccg
    10561 aactcaacca gattctcccc acatcaccag caatttgcgg gcatatccca attcgggaaa
    10621 atttgttcct gagctatagc actaactgac gtgaaatgtc gtgcggcccc gtgatgctgt
    10681 tgaacgtcaa atgacgtcat caggagcgta acgcatccat aaagcacaac accggtctga
    10741 acggcgactg atgagatttt ctgaatgaga acaaagagaa atgtatcagt tcgcttgctc
    10801 atgcaaagac taacaatcca ttaaaatagt aagtgctccg gacaattttc catggattat
    10861 tttctgaaca tttttctttg gcaaagatga tgaattttga tggtaaggaa tattacttct
    10921 ggttctcagt aaaatccttt cgtaatacta tgtaatcaag aagtttatgg ctggtaaaaa
    10981 taacgtcttg cattcaccaa taatatgtaa ataaacccat ctatagatgg taaaaatagg
    11041 ttgtggcaat tatcattgca tcattccctt ttcgaatgag tttctattat gcaacaacct
    11101 gtagttcgcg ttggcgaatg gcttgttact ccgtccataa accaaattag ccgcaatggg
    11161 cgtcaactta cccttgagcc gagattaatc gatcttctgg ttttctttgc tcaacacagt
    11221 ggcgaagtac ttagcaggga tgaacttatc gataatgtct ggaagagaag tattgtcacc
    11281 aatcacgttg tgacgcagag tatctcagaa ctacgtaagt cattaaaaga taatgatgaa
    11341 gatagtcctg tctatatcgc tactgtacca aagcgcggct ataaattaat ggtgccggtt
    11401 atctggtaca gcgaagaaga gggagaggaa ataatgctat cttcgcctcc ccctatacca
    11461 gaggcggttc ctgccacaga ttctccctcc cacagtctta acattcaaaa caccgcaacg
    11521 ccacctgaac aatccccagt taaaagcaaa cgattcacta ccttttgggt atggtttttt
    11581 ttcctgttgt cgttaggtat ctgtgtagca ctggtagcgt tttcaagtct tgatacacgt
    11641 cttcctatga gcaaatcgcg tattttgctc aatccacgcg atattgacat taatatggta
    11701 aataaaagtt gtaacagctg gagttccccg tatcagctct cttacgcgat aggcgtgggt
    11761 gatttggtgg cgacatcact taacaccttc tccaccttta tggtgcatga caaaatcaac
    11821 tacaacattg atgaaccgag cagttccggt aaaacattat ctattgcgtt tgttaatcag
    11881 cgccaatacc gtgctcaaca atgctttatg tcgataaaat tggtagacaa tgcagatggt
    11941 tcaaccatgc tggataaacg ttatgtcatc actaacggta atcagctggc gattcaaaat
    12001 gatttactgg agagtttatc aaaagcgtta aaccaaccgt ggccacaacg aatgcaggag
    12061 acgctccaga aaattttgcc gcatcgtggt gcgttattaa ctaattttta tcaggcacat
    12121 gattatttac tgcatggcga tgataaatca ttgaaccgtg ccagtgaatt attaggtgag
    12181 attgttcaat catccccaga atttacctac gcgagagcag aaaaagcatt agttgatatc
    12241 gtgcgccatt ctcaacatcc tttagatgaa aaacaattag cagcactgaa cacagaaata
    12301 gataacattg ttacactgcc ggaattgaac aacctgtcca ttatatatca aataaaagcg
    12361 gtcagtgctc tggtaaaagg taaaacagat gagtcttacc aggcgataaa tactggcatt
    12421 gatcttgaaa tgtcctggct aaattatgtg ttgcttggca aggtttatga aatgaagggg
    12481 atgaaccggg aagcagctga tgcatatctc accgccttta atttacgccc aggggcaaac
    12541 accctttact ggattgaaaa tggtatattc cagacttctg ttccttatgt tgtaccttat
    12601 ctcgacaaat ttcttgcttc agaataagta actccgggtt gatttatgct cggaaatatt
    12661 tgttgttgag tttttgtatg ttcctgttgg tataatatgt tgcggcaatt tatttgccgc
    12721 ataattttta ttacataaat ttaaccagag aatgtcacgc aatccattgt aaacattaaa
    12781 tgtttatctt ttcatgatat caacttgcga tcctgatgtg ttaataaaaa acctcaagtt
    12841 ctcacttaca gaaacttttg tgttatttca cctaatcttt aggattaatc cttttttcgt
    12901 gagtaatctt atcgccagtt tggtctggtc aggaaatagt tatacatcat gacccggact
    12961 ccaaattcaa aaatgaaatt aggagaagag catgagttct gccaagaaga tcgggctatt
    13021 tgcctgtacc ggtgttgttg ccggtaatat gatggggagc ggtattgcat tattacctgc
    13081 gaacctagca agtatcggtg gtattgctat ctggggttgg attatctcta ttattggtgc
    13141 aatgtcgctg gcgtatgtat atgcccgact ggcaacaaaa aacccgcaac aaggtggccc
    13201 aattgcttat gccggagaaa tttcccctgc atttggtttt cagacaggtg ttctttatta
    13261 ccatgctaac tggattggta acctggcgat tggtattacc gctgtatctt atctttccac
    13321 cttcttccca gtattaaatg atcctgttcc ggcgggtatc gcctgtattg ctatcgtctg
    13381 ggtatttacc tttgtaaata tgctcggcgg tacttgggta agccgtttaa ccactattgg
    13441 tctggtgctg gttcttattc ctgtggtgat gactgctatt gttggctggc attggtttga
    13501 tgcggcaact tatgcagcta actggaatac tgcggatacc actgatggtc atgcgatcat
    13561 taaaagtatt ctgctctgcc tgtgggcctt cgtgggtgtt gaatccgcag ctgtaagtac
    13621 tggtatggtt aaaaacccga aacgtaccgt tccgctggca accatgctgg gtactggttt
    13681 agcaggtatt gtttacatcg ctgcgactca ggtgctttcc ggtatgtatc cgtcttctgt
    13741 aatggcggct tccggtgctc cgtttgcaat cagtgcttca actatcctcg gtaactgggc
    13801 tgcgccgctg gtttctgcat tcaccgcctt tgcgtgcctg acttctctgg gctcctggat
    13861 gatgttggta ggccaggcag gtgtacgtgc cgctaacgac ggtaacttcc cgaaagttta
    13921 tggtgaagtc gacagcaacg gtattccgaa aaaaggtctg ctgctggctg cagtgaaaat
    13981 gactgccctg atgatcctta tcactctgat gaactctgcc ggtggtaaag catctgacct
    14041 gttcggtgaa ctgaccggta tcgcagtact gctgactatg ctgccgtatt tctactcttg
    14101 cgttgacctg attcgttttg aaggcgttaa catccgcaac tttgtcagcc tgatctgctc
    14161 tgtactgggt tgcgtgttct gcttcatcgc gctgatgggc gcaagctcct tcgagctggc
    14221 aggtaccttc atcgtcagcc tgattatcct gatgttctac gctcgcaaaa tgcacgagcg
    14281 ccagagccac tcaatggata accacaccgc gtctaacgca cattaattaa aagtattttc
    14341 cgaggctcct cctttcattt tgtcccatgt gttgggaggg gcctttttta cctggagata
    14401 tgactatgaa cgttattgca atattgaatc acatgggggt ttattttaaa gaagaaccca
    14461 tccgtgaact tcatcgcgcg cttgaacgtc tgaacttcca gattgtttac ccgaacgacc
    14521 gtgacgactt attaaaactg atcgaaaaca atgcgcgtct gtgcggcgtt atttttgact
    14581 gggataaata taatctcgag ctgtgcgaag aaattagcaa aatgaacgag aacctgccgt
    14641 tgtacgcgtt cgctaatacg tattccactc tcgatgtaag cctgaatgac ctgcgtttac
    14701 agattagctt ctttgaatat gcgctgggtg ctgctgaaga tattgctaat aagatcaagc
    14761 agaccactga cgaatatatc aacactattc tgcctccgct gactaaagca ctgtttaaat
    14821 atgttcgtga aggtaaatat actttctgta ctcctggtca catgggcggt actgcattcc
    14881 agaaaagccc ggtaggtagc ctgttctatg atttctttgg tccgaatacc atgaaatctg
    14941 atatttccat ttcagtatct gaactgggtt ctctgctgga tcacagtggt ccacacaaag
    15001 aagcagaaca gtatatcgct cgcgtcttta acgcagaccg cagctacatg gtgaccaacg
    15061 gtacttccac tgcgaacaaa attgttggta tgtactctgc tccagcaggc agcaccattc
    15121 tgattgaccg taactgccac aaatcgctga cccacctgat gatgatgagc gatgttacgc
    15181 caatctattt ccgcccgacc cgtaacgctt acggtattct tggtggtatc ccacagagtg
    15241 aattccagca cgctaccatt gctaagcgcg tgaaagaaac accaaacgca acctggccgg
    15301 tacatgctgt aattaccaac tctacctatg atggtctgct gtacaacacc gacttcatca
    15361 agaaaacact ggatgtgaaa tccatccact ttgactccgc gtgggtgcct tacaccaact
    15421 tctcaccgat ttacgaaggt aaatgcggta tgagcggtgg ccgtgtagaa gggaaagtga
    15481 tttacgaaac ccagtccact cacaaactgc tggcggcgtt ctctcaggct tccatgatcc
    15541 acgttaaagg tgacgtaaac gaagaaacct ttaacgaagc ctacatgatg cacaccacca
    15601 cttctccgca ctacggtatc gtggcgtcca ctgaaaccgc tgcggcgatg atgaaaggca
    15661 atgcaggtaa gcgtctgatc aacggttcta ttgaacgtgc gatcaaattc cgtaaagaga
    15721 tcaaacgtct gagaacggaa tctgatggct ggttctttga tgtatggcag ccggatcata
    15781 tcgatacgac tgaatgctgg ccgctgcgtt ctgacagcac ctggcacggc ttcaaaaaca
    15841 tcgataacga gcacatgtat cttgacccga tcaaagtcac cctgctgact ccggggatgg
    15901 aaaaagacgg caccatgagc gactttggta ttccggccag catcgtggcg aaatacctcg
    15961 acgaacatgg catcgttgtt gagaaaaccg gtccgtataa cctgctgttc ctgttcagca
    16021 tcggtatcga taagaccaaa gcactgagcc tgctgcgtgc tctgactgac tttaaacgtg
    16081 cgttcgacct gaacctgcgt gtgaaaaaca tgctgccgtc tctgtatcgt gaagatcctg
    16141 aattctatga aaacatgcgt attcaggaac tggctcagaa tatccacaaa ctgattgttc
    16201 accacaatct gccggatctg atgtatcgcg catttgaagt gctgccgacg atggtaatga
    16261 ctccgtatgc tgcattccag aaagagctgc acggtatgac cgaagaagtt tacctcgacg
    16321 aaatggtagg tcgtattaac gccaatatga tccttccgta cccgccggga gttcctctgg
    16381 taatgccggg tgaaatgatc accgaagaaa gccgtccggt tctggagttc ctgcagatgc
    16441 tgtgtgaaat cggcgctcac tatccgggct ttgaaaccga tattcacggt gcataccgtc
    16501 aggctgatgg ccgctatacc gttaaggtat tgaaagaaga aagcaaaaaa taattagctc
    16561 gtacaaggga agtggcttgc cacttccctt ttttgctcat aaggagaaca catgaaaaca
    16621 ccctcacagc cgcgcgcgat atactatatc gtggcgatcc aaatctggga gtacttcagt
    16681 ttttacggca tgcgtgcctt actcattctc tatctcaccc atcagcttgg ttttgatgat
    16741 aaccatgcca tcagcctgtt cagcgcatat gcttctctgg tttacgttac ccctattctc
    16801 ggcggctggc ttgccgaccg cctgctcggc aaccgcactg cagtgattgc cggcgcgctg
    16861 ttaatgaccc ttggccatgt ggtgctgggt attgatacaa attcaacctt tagcctgtat
    16921 ctggcgccgg caatcattat ttgtggctac ggtttattca aatcaaacat cagctgtttg
    16981 cttggcgagc tctacgacga gaacgatcat cgacgtgatg gcggtttttc gctgctgtat
    17041 gctgcgggca atatcggttc tatcgcagcc ccaatcgcct gcggcctggc tgctcagtgg
    17101 tatggatggc atgttggctt tgcccttgcg ggtggcggca tgtttatcgg tttgttgatt
    17161 ttcttaagcg gtcatcgtca tttccagtcc acacgtagta tggataaaaa agcgctcact
    17221 agtgtcaaat ttgccttacc agtatggagc tggttagtgg tgatgctctg tttagcccca
    17281 gtatttttta ctctgctgct ggagaacgac tggtccggat atttgctggc gatcgtttgc
    17341 ctcattgccg cacaaatcat tgcccgcatg atgatcaaat tccccgaaca tcgccgtgct
    17401 ctttggcaaa ttgtattgtt gatgtttgtc gggacattgt tctgggtact ggcacaacag
    17461 ggcggcagta ccatcagctt gtttatcgat cgctttgtga atcgtcaggc attcaatatt
    17521 gaagtaccta cagcactatt ccagtcggtg aatgcaattg cggtgatgct cgctggggtt
    17581 gtactggcct ggctggcgtc gccagaaagc cgcggcaact caacattgcg cgtctggctg
    17641 aagtttgcct ttggcttact gctgatggct tgtggcttta tgttgttggc atttgatgcc
    17701 cgacatgcag cggctgacgg tcaagcgtca atgggcgtga tgatatccgg gctggcgcta
    17761 atgggctttg ccgaactctt tattgacccg gtggcgattg cgcaaatcac gcgtctgaaa
    17821 atgtctggcg tattaaccgg gatttatatg ctggcaacag gcgcggtcgc caactggctg
    17881 gcaggcgtcg tggcacagca gacgacagag tcgcaaatta gcggtatggc aattgcagct
    17941 taccagcgat tcttttctca gatgggagag tggacgttgg cttgtgtcgc gatcatcgtc
    18001 gtattggcct ttgctacccg ttttctgttt agcacgccga cgaatatgat acaggagagc
    18061 aacgattaac tgtcgtaaaa acaattggtt atgaataaa
//
LOCUS       DAPHKZ010000090        18064 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.090, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000090 DAPHKZ010000000
VERSION     DAPHKZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18064
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.090"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(246..1838)
                     /gene="lsrK"
                     /locus_tag="RH288_003198"
     CDS             complement(246..1838)
                     /gene="lsrK"
                     /locus_tag="RH288_003198"
                     /EC_number="2.7.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416028.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer-2 kinase"
                     /protein_id="HDV4032229.1"
                     /translation="MARLFTPSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWR
                     HLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNE
                     GTPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSD
                     IYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADIL
                     SPVKETGTLLGVVSSQAAELCGLKAGTTVVVGGGDVQLGCLGLGVVRPAQTAVLGGTF
                     WQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAE
                     RLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKAT
                     LFRALEENAAIVSACNLQQIADFSNIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIP
                     VVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAV
                     YQDQLGLVDHGLTTSLWKAPGL"
     gene            complement(1917..2870)
                     /gene="lsrR"
                     /locus_tag="RH288_003199"
     CDS             complement(1917..2870)
                     /gene="lsrR"
                     /locus_tag="RH288_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LsrR"
                     /protein_id="HDV4032230.1"
                     /translation="MTINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTR
                     LKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRL
                     GIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
                     GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDD
                     ATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTI
                     PVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS"
     gene            3119..4654
                     /gene="lsrA"
                     /locus_tag="RH288_003200"
     CDS             3119..4654
                     /gene="lsrA"
                     /locus_tag="RH288_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter ATP-binding
                     protein LsrA"
                     /protein_id="HDV4032231.1"
                     /translation="MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLG
                     GNGAGKSTLMKIIAGITPADSGTLKIGGNNYARLTPVHAHQLGIYLVPQEPLLFPSLS
                     IKENILFGLAKKQLSMQKMKNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSR
                     ILILDEPTASLTPAETERLFSRLQELLATGVGIVFISHKLPEIRQIADRISVMRDGTI
                     ALSGKTSELSTDDIIQAITPVVREKSLSASQKLWLELPGNRPQHAAGTSVLTLENLTG
                     EGFRNVSLTLNAGEILGLAGLVGAGRTELAETLYGLRTLRGGSIMLNGKEINRLSTGE
                     RLLRGLVYLPEDRQSSGLNLDASLAWNVCALTHNLRGFWAKTAKDNATLERYRRALNI
                     KFNQPEQAARTLSGGNQQKILIAKCLEASPQALIVDEPTRGVDVSARNDIYQLLRSIA
                     AQNVAVLLISSDLEEIELMADRVYVMHQGEITHSALTGRDINVETIMRVAFGDSQRQE
                     ASC"
     gene            4648..5676
                     /gene="lsrC"
                     /locus_tag="RH288_003201"
     CDS             4648..5676
                     /gene="lsrC"
                     /locus_tag="RH288_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrC"
                     /protein_id="HDV4032232.1"
                     /translation="MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSA
                     QILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLA
                     GFFNGVLVAWLKIPAIVATLGSLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVS
                     AIGWLTIILVAFMAWLLAKTAFGRSFNATGDNLQGARQLGVRTEAIRIVAFSLNGCMA
                     ALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQID
                     SVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKYARFMTPPPSVKPAS
                     SGKKREAA"
     gene            5676..6668
                     /gene="lsrD"
                     /locus_tag="RH288_003202"
     CDS             5676..6668
                     /gene="lsrD"
                     /locus_tag="RH288_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrD"
                     /protein_id="HDV4032233.1"
                     /translation="MRIRYGWELALAALLVIEIVAFGAINPRMLDLNMLLFSTSDFIC
                     IGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGVLCGL
                     INAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
                     LGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMT
                     GLASAVAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLV
                     GYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEWLARRANNPLP"
     gene            6680..7702
                     /gene="lsrB"
                     /locus_tag="RH288_003203"
     CDS             6680..7702
                     /gene="lsrB"
                     /locus_tag="RH288_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein LsrB"
                     /protein_id="HDV4032234.1"
                     /translation="MTLHRFKKIALLSVLGIAAISMNVQAAERIAFIPKLVGVGFFTS
                     GGNGAQQAGKELGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPAL
                     KRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYS
                     SPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAII
                     APDANALPAAAQAAENLKNDKVAIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISV
                     YVADALLKKGSMKTGDKLDIQGVGQVEVSPNSVQGYDYEADGNGIVLLPERVIFNKEN
                     IGKYDF"
     gene            7729..8604
                     /gene="lsrF"
                     /locus_tag="RH288_003204"
     CDS             7729..8604
                     /gene="lsrF"
                     /locus_tag="RH288_003204"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HDV4032235.1"
                     /translation="MADLDDIKDGKDFRTDQPQQNIPFTLKGCGALDWGMQSRLSRIF
                     NPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNK
                     PVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
                     DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVEKGFERIVAGC
                     PVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHN
                     ETADRAYELYLSEKQ"
     gene            8628..8918
                     /gene="lsrG"
                     /locus_tag="RH288_003205"
     CDS             8628..8918
                     /gene="lsrG"
                     /locus_tag="RH288_003205"
                     /EC_number="5.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione
                     isomerase"
                     /protein_id="HDV4032236.1"
                     /translation="MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDP
                     EVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP"
     gene            8975..9733
                     /gene="tam"
                     /locus_tag="RH288_003206"
     CDS             8975..9733
                     /gene="tam"
                     /locus_tag="RH288_003206"
                     /EC_number="2.1.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="HDV4032237.1"
                     /translation="MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGN
                     STALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANAS
                     LQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA
                     GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFL
                     KRYHQMLEEQYPLQENGQILLAFPRLFIVARRME"
     gene            complement(9737..10651)
                     /locus_tag="RH288_003207"
     CDS             complement(9737..10651)
                     /locus_tag="RH288_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family protein"
                     /protein_id="HDV4032238.1"
                     /translation="MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPW
                     YTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKT
                     TLPDSASVREFARLQIAFAHCLRMTLRKQPQAEVLAHYLKTKDLQRVLASNSPANRIL
                     LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDEAEIPAKILPDRHYQLT"
     gene            complement(10858..12309)
                     /gene="uxaB"
                     /locus_tag="RH288_003208"
     CDS             complement(10858..12309)
                     /gene="uxaB"
                     /locus_tag="RH288_003208"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDV4032239.1"
                     /translation="MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDL
                     NSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEY
                     DEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
                     LDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTG
                     YPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKP
                     YKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRD
                     ELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFA
                     LAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWE
                     QDLTQVPGLVEQVANDLDAILEKGMREAVRPLC"
     gene            complement(12536..13954)
                     /locus_tag="RH288_003209"
     CDS             complement(12536..13954)
                     /locus_tag="RH288_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDV4032240.1"
                     /translation="MHVHPISTFRLFQEGHLLRNSIAIFALTTLFYFIGAELRLVHEL
                     SLFWPLNGVMAGVFARYVWLNRLHYYAISYVAMLVYDAITTEWGLVSLAINFSNMMFI
                     VTVALLVVRDKRLGKNKYEPVSALRLFNYCLIAALLCAIVGAIGSVSIDSLDFWPLLA
                     DWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALIVSVIASVVIGGAGSLAF
                     PLPALIWCAVRYTPQVTCLLTFVTGAVEIVLVANSVIDISVGSPFSIPEMFSARLGIA
                     TMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGLYEALKSLSLKQTQHLTV
                     MLLDIDYFKSINDNYGHECGDKVLSVFARHIQKIVGDKGLVARMGGEEFAVAVPSVNP
                     VDGLLMAEKIRKGVELQPFTWQQKTLYLTVSIGVGSGRASYRTLTDDFNKLMVEADTC
                     LYRSKKDGRNRTSTMRYGEEVV"
     gene            complement(14093..14452)
                     /locus_tag="RH288_003210"
     CDS             complement(14093..14452)
                     /locus_tag="RH288_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HDV4032241.1"
                     /translation="MQSLDPLFARLSRSKFRSRFRLGMKERQYCLEKGAPVIEQHAAD
                     FVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGVSLSEEQQR
                     YIVAVIYHWLVVQMNQP"
     gene            complement(14452..15378)
                     /gene="glsB"
                     /locus_tag="RH288_003211"
     CDS             complement(14452..15378)
                     /gene="glsB"
                     /locus_tag="RH288_003211"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HDV4032242.1"
                     /translation="MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIA
                     ICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKA
                     IHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY"
     gene            complement(15442..16830)
                     /gene="sad"
                     /locus_tag="RH288_003212"
     CDS             complement(15442..16830)
                     /gene="sad"
                     /locus_tag="RH288_003212"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HDV4032243.1"
                     /translation="MTITPATHAISINPATGEQLSVLPWAGADDIENALQLAAAGFRD
                     WRETNIDYRAEKLRDIGKALRARSEEMAQMITREMGKPINQARAEVAKSANLCDWYAE
                     HGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
                     HAPNVMGCAQLIAQVFKDAGIPQGVYGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFII
                     EEGIASAFTERFVAAAAALKMGDPRDEENALGPMARFDLRDELHHQVEKTLAQGARLL
                     LGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITIAKDAEHALELANDSEFG
                     LSATIFTTDETQARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNIQTVWKDRI"
     gene            16931..17812
                     /locus_tag="RH288_003213"
     CDS             16931..17812
                     /locus_tag="RH288_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4032244.1"
                     /translation="MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELG
                     VDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAV
                     RIPATLAEFNRRYPKIQFSLSTGPSGTMLDGVLEGKLNAAFIDGPINHTAIDGIPVYR
                     EELMIVTPQGYAPVTRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESY
                     HGMLACVIAGAGIALIPRSMLESMPGHHQVEAWPLAEQWRWLTTWLVWRRGAKTRPLE
                     AFIQLLDVPDSARQGYQ"
     gene            17890..>18064
                     /gene="yneK"
                     /locus_tag="RH288_003214"
     CDS             17890..>18064
                     /gene="yneK"
                     /locus_tag="RH288_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
                     /protein_id="HDV4032245.1"
                     /translation="MVTPVSISNYISLPDDFPVRNIAPQVKEVLKDFIDALSTIICNE
                     EWRTSLNINSATKK"
BASE COUNT         4520 a         4603 c         4510 g         4431 t
ORIGIN      
        1 taaaaatcga agtttattaa accccttttg catccattag tgtctttagg aatattcgct
       61 ataaaataag ggttgtgctt aatgctttaa gaaaaatagc aattttccct tgaatatagt
      121 actggtgatg gaacgatgaa tctgcaagct ggcttttaac aagccagctc taaaagaagg
      181 gaaataagaa taactatact caaaaactaa cagccacggt catcatgatg tggctgtcaa
      241 tgaaactata acccaggcgc tttccataac gacgtcgtca gtccatgatc aaccagcccc
      301 agctgatcct gataaactgc ctgccactta tcgcgtgaat cctgataaag ttcatgcttt
      361 tccgggtctg gtgtgtgcgt ccgttcccag cgaaccaggc gttctccggt ttctgccatt
      421 gatgaaaaaa ttccggcacc gacgccagct gcaatggcac atcctaatgc agtggcttct
      481 ttgaccaccg gaatattgac gggtaatccc gagacatcag cgagaatttg actccataat
      541 ttcccttttg aacctccgcc tgcaaagact aacgatgaag gatgaatatt cgagaaatca
      601 gcaatttgct gcaagttaca cgctgataca atcgccgcat tttcttccag cgcacggaac
      661 aatgtcgctt tgttacattt atccgggtca atggacaagt taataaagga aggcgcagcg
      721 tgataccagg ttttaaagcg cattctgtcg gagaagatcg gcattacgcc ccacgaccca
      781 ggcggcaccc gactggccat ctcttccagc agcgtatagg tgtcgatgcc taaacgttcg
      841 gcaatcagtt tttcttcggc acagaaagca tcgcggaacc agcgcatggt gagtccggta
      901 aaaaagctta tagattcagc ttgtaccatg ccaggaataa catgaggatt aacgcgcacg
      961 ttcatttctg ggtctgtcac cggcgcggct aaatttacaa cttgctgcca gaatgtgccg
     1021 ccaagaaccg cggtttgtgc cggacgcaca acgcctaacc caaggcaacc aagctgcacg
     1081 tcgcctcctc caacgaccac cgtagtgccc gccttcagac cgcagagttc cgccgcttgt
     1141 gaacttacca cgcccagcaa tgtgccggtt tctttgacag gagaaagaat atcggcacgt
     1201 aggccagcca tatccagcaa tgcaggtttc cagtcacggg tggttagatc aagaagtccc
     1261 gtggtgccag cgttagaggg atccaccgcc agttcgccgc tgagcatata ggccagccag
     1321 tcgctgatca tggtgatggt tgatgcctga cggtaaatat cggaacgatg gtgcgccagc
     1381 caaagtaatc tggggatggc acttaaagcc agcgtttgtc cggtcgcgcg ataaacttcg
     1441 ttttcaaagg tattgttgtg cagttcttta agttcgctaa cttcgcgcgc cgctctggca
     1501 tccacattgg cgcaggccca gatcggtgtt ccttcattgt tatataaaac aatgccttca
     1561 cgcatcgaac atgccgaaac ggcagcgata tactccgggg ctatgccggc gttgtgcaac
     1621 gcctggcgca tacactcaca cgccagttgc cagtttttgt tgagatcaaa ttccatagaa
     1681 ccaggaacgt ccggtactgc cagatgccgc cactccgcct gtcccactgc tatttgattg
     1741 ccttccaggt cgaatatcac agcccgaata cttccggtgc ctgcatccag cgccatcagg
     1801 tagtactttg attctgaagg ggtaaagagt cgagccatta gattatcctc ggcttatgcg
     1861 ttctgtctgt tcctctatac gttctccatc attcccggta ataaggtcat gcaaatttaa
     1921 ctacgtaaaa tcgccgctgc tgtgtcctga tcggtaacca gtgcgttgat ataaccgcct
     1981 ttcattgcag cggcaattgc ttcggcttta ttttctcccc ctgccacgcc aacccggacg
     2041 ggtatggtct tcagcgcgct taaaggtaag ccaatcagtt cgttatgtat tttgatatcc
     2101 gtgacaacgt caccttttgc atcaaaaaag tagcctaaaa tgtcgccaac cgcccctttt
     2161 cggccaatca ttaactgttc gccctggctg atataaccgg agcgaatgat tgtcgcatcg
     2221 tcctgttgac tcacagcacc aatgccgaca atcgccacat ccgctgcttg cgcggctagc
     2281 agaacatctt tgacgcaatt ttcatttttt agcgtacggg caatgtcagc ggaggatgcc
     2341 cgcaacggag ccggaataat attcacactg cacgccgcgt taagctgccc gatacccgtc
     2401 atataagaac cgactccacc ggagagcgtg accaggcgaa tttgctgtga cgaaataaaa
     2461 ccacttaagc gttgcagcgt attcatggtt gcctcgccaa aaccaatcgc cagcatctgt
     2521 tgtggttgaa gtaaactcat caacatatgc gccgcgccta tccctagtcg cccgccgaca
     2581 tcagcatccg caagccctgg gatcacccgg acatgttgca gcgaaaactg acgacgtaat
     2641 tgtgtttcat attccagaca gccttcaaag cgagaattaa tctgtacgcg aataatgccg
     2701 gattgatgcc ctttctccag taatcgcgac actttcaaac gggtcaggcc gagacgatcg
     2761 ctgatctcac tctgggtcag cccgtcgtgg tagtaaaacc acgcgatccg cgcgacctgt
     2821 tcttcttcac acattccctg ttctgaaatt accgaatcgt tgattgtcat aattcattct
     2881 tcactttgaa catatttaaa tctttaatgc aattgttcag ttcttgcgca tttatatctg
     2941 tgatggcaac cacagtttga ctctacgagt atgaacaaac gcaaccgtga aaatcaaaat
     3001 agcataaatt gtgatctatt cgtcggaaat atgtgcaatg tccacctaag gttatgaaca
     3061 aattaaaagc agaaatacat ttgttcaaaa ctcacctgca aaactgaacg ggggaaatat
     3121 gcaaacgagt gatacccgcg cgttaccgct actttgcgcc cgctcggttt ataaacagta
     3181 ttcaggggtc aatgtcctga aaggcatcga ttttacgttg catcaggggg aggtccacgc
     3241 cctgctcggc ggcaatggtg ccggtaaatc gacgttaatg aagattattg ccggtattac
     3301 ccctgctgat agcggtacgc tgaagattgg gggcaacaac tacgccagat taacgccagt
     3361 tcatgctcat cagctgggta tttatctcgt tccccaggaa ccgctgcttt ttccaagcct
     3421 gtcgataaaa gaaaacatcc tgtttgggct ggcaaaaaaa cagctctcca tgcagaaaat
     3481 gaagaacttg ctggcggcgc tgggctgcca gtttgatctg catagtctgg caggatcgct
     3541 ggatgtcgcc gatcgccaaa tggtggaaat cctccgcggg ctgatgcgcg actcgcggat
     3601 tctgatcctc gatgaaccta ccgcctcgct tacccctgcg gaaaccgaac gcttgtttag
     3661 tcgcttgcaa gagctgcttg ctactggcgt gggtattgtt tttatctcgc ataagctgcc
     3721 ggaaattcgc cagattgccg atcgaattag cgtgatgcgc gacggaacca tcgccttaag
     3781 cggcaaaacc agcgaactgt ctaccgacga cattattcag gccatcacgc cagtggtacg
     3841 agaaaaatcg ctctctgcca gccaaaaatt atggctggag ttacctggta accgcccaca
     3901 acatgccgcc ggaacgtcgg tgctgacact ggaaaatctg actggcgaag gtttcaggaa
     3961 tgtcagcctg acgctcaatg ccggagaaat tctgggcctg gctgggctgg tgggagccgg
     4021 acgcacagaa ctggccgaga cgctctatgg tctgcgtact ttgcgtggcg gaagcattat
     4081 gctgaatggt aaagagatca atagattatc caccggagaa cgtttactgc gcggtctggt
     4141 ttatctgccg gaagatcgcc agtcatccgg actgaatctc gatgcttcac tggcgtggaa
     4201 cgtctgcgcc cttactcata accttcgtgg attctgggcg aaaaccgcga aagataatgc
     4261 caccctggaa cgatatcgtc gggcgctgaa tattaaattt aaccaaccgg aacaagctgc
     4321 acggacatta tccggtggca accagcaaaa aatcctcatt gccaaatgcc tggaagcttc
     4381 gccgcaagca ttgattgtcg atgagccgac gcgcggcgtg gatgtctcag cccgtaatga
     4441 tatctaccag ctgttgcgca gcatcgccgc acagaatgtg gcagtgctgc ttatctcctc
     4501 tgatctggaa gagatcgaac tgatggcaga tcgtgtgtat gtgatgcatc agggcgaaat
     4561 tacccactct gcactgaccg ggcgcgatat taatgtcgag actattatgc gcgttgcctt
     4621 cggcgatagt cagcgtcagg aggcgtcatg ctgaagttta ttcagaacaa ccgtgaaatc
     4681 acggcactgc tggcggtggt gctgctgttt gtattacccg gttttctcga ccgccagtat
     4741 ttaagtgtgc aaacgctgac catggtttat agcagcgcgc aaatcctgat cctgctggca
     4801 atgggcgcga cgctggtaat gcttacgcgc aatattgatg tttcagtggg ttcgattacc
     4861 ggaatgtgcg cggtgctgtt ggggatgtta ctgaacgcag gatattcact acctgttgcc
     4921 tgtgtcgcga ctttactgct tggtttgctc gcgggatttt tcaacggtgt cctggtcgcg
     4981 tggctaaaga tccctgccat tgttgccacc cttggctcgt tagggttgta cagaggcatc
     5041 atgttgctgt ggactggcgg taaatggatt gaggggttac ccgccgaact gaaacagctc
     5101 tccgccccgc tgctgcttgg cgtttcagca attggttggt taacgataat tctggtggca
     5161 tttatggcct ggctgctggc aaagacggcg tttggacgca gttttaatgc cacgggcgat
     5221 aatttacagg gagctcgtca actgggcgtt cgtacggaag ccattcgcat tgtggcattt
     5281 tcgttgaacg gctgcatggc ggcactggcg gggattgtgt ttgcttcgca gattggtttt
     5341 atccccaacc agaccggtac cgggctggag atgaaagcaa ttgcagcctg cgtgctgggc
     5401 ggcattagtt tgctcggcgg ttccggtgcg atcatcggtg cggtactcgg cgcatggttc
     5461 ctgacgcaga tcgatagcgt actggtgctg ttgcgcattc cggcatggtg gaacgatttt
     5521 atcgcgggcc tcgtgctgct agcggtgctg gtgtttgatg gacgcctgcg ttgtgcgctg
     5581 gaacgtaatc tgcggcggca aaaatatgcc cgctttatga cgccaccgcc atccgttaaa
     5641 cccgcttcgt caggtaaaaa acgggaggcc gcataatgcg tattcgctac ggttgggaac
     5701 tggctcttgc cgcactgctc gttattgaga ttgtcgcatt tggtgcaatt aacccgcgga
     5761 tgttagatct caatatgttg ctgttcagca ccagtgactt tatctgcatt ggcattgtcg
     5821 ccctaccgct gacgatggtg attgtcagtg gcgggatcga tatttcgttt ggttcgacca
     5881 tcggcctctg cgccattgca ttgggcgtac tgtttcaaag tggtgtgccg atgccgctgg
     5941 cgatactcct gaccttactg ctcggcgtat tgtgcgggct gatcaacgcc ggattaatta
     6001 tctataccaa agttaacccg ctggtgatta cgcttggcac gctgtatctg tttgccggaa
     6061 gtgccctgct gctttccggg atggccggag cgacggggta cgaaggtatt ggtggattcc
     6121 cgatggcgtt tacagatttc gctaacctgg atgtgctggg gctccccgtt ccgctgatta
     6181 tcttcctgat atgtctcctc gttttctggc tctggctgca taaaacccat gccggacgta
     6241 atgtgttttt gattgggcaa agcccgcgcg tggcgcttta tagcgcgatt ccagttaacc
     6301 gcaccttatg tgcgctctat gccatgacgg ggctggcgtc tgcggtcgcc gctgtgctgc
     6361 tggtatcgta ttttggttca gcacgttccg atctcggtgc gtcgtttctg atgcccgcca
     6421 tcaccgccgt ggtgcttggc ggtgccaata tttatggtgg ttccggttcc attatcggca
     6481 ccgccattgc ggttttatta gtgggatatt tgcaacaagg tttgcaaatg gcaggagtgc
     6541 caaatcaggt gtccagcgcc ctttccggtg cgctacttat cgtcgttgtc gtaggtcgtt
     6601 ccgttagcct gcatcgccag caaattaaag agtggctggc gcgtcgggcc aataacccat
     6661 tgccataaag gatatcttca tgacacttca tcgctttaag aaaatcgcct tacttagcgt
     6721 tcttggcatt gccgcaatct ctatgaatgt gcaggccgca gagcgtattg catttattcc
     6781 aaaactggtt ggcgtgggat tttttaccag cggtggcaac ggcgcacaac aagcgggtaa
     6841 agagctgggc gttgatgtga cctacgacgg gccgacagaa cccagtgttt ctggtcaggt
     6901 acagttgatt aataacttcg tcaatcaagg ttataacgcc attatcgttt ctgcggtttc
     6961 gcctgatggc ttgtgtccgg cactgaaacg cgccatgcaa cgtggtgtga gagtgctgac
     7021 ctgggactct gatactaaac cggagtgccg ctcttactac attaatcagg gaacgcccgc
     7081 ccagttggga ggtatgttgg tggatatggc tgcgcgtcag gtgaataaag acaaagccaa
     7141 agtcgcgttt ttctactcaa gccccaccgt tacggaccaa aaccagtggg tgaaagaagc
     7201 gaaagcgaaa atcgccaaag agcatccagg ctgggaaatt gtcactacgc agtttggcta
     7261 taacgatgcc actaaatcgt tacaaaccgc agaaggaata ttaaaagcgt atagcgatct
     7321 cgacgccatt atcgcccccg atgccaacgc cctgcccgct gccgcacaag ccgcagaaaa
     7381 cctgaaaaat gacaaagttg cgattgtcgg attcagtacg ccaaacgtga tgcgtccata
     7441 tgtggaacgc ggcacggtga aagaatttgg cctgtgggat gtggttcagc aaggcaaaat
     7501 ttcagtgtat gtcgcggatg cattattgaa aaaaggatca atgaaaacgg gcgacaagct
     7561 ggatatccag ggcgtaggtc aggttgaagt ctcgccaaac agcgttcagg gctatgacta
     7621 cgaagcggat ggtaatggca tcgtactgtt accggagcgc gtgatattca acaaagagaa
     7681 tatcggcaaa tacgatttct gatgtgcatt acttaaccgg agtaagttat ggcagattta
     7741 gacgatatta aagatggtaa agattttcgt accgatcaac cgcaacaaaa tatccctttt
     7801 accctgaaag gttgcggtgc gctggattgg ggaatgcagt cacgcttatc gcggatattt
     7861 aatccgaaaa cgggtaaaac cgtgatgctg gcctttgatc atggttattt tcaggggccg
     7921 actaccggac ttgaacgcat tgatataaat atcgccccgc tgtttgaaca tgccgatgta
     7981 ttaatgtgta cgcgcggcat tttgcgcagc gtagttcccc cggcgaccaa taagccggtg
     8041 gtactgcggg cgtcaggtgc gaactctatt ctggcggaat taagtaatga agccgtggcg
     8101 ttatcgatgg atgatgccgt gcgcctgaac agttgcgcgg tggcggcgca ggtttatatc
     8161 ggcagcgaat atgaacatca gtcgatcaaa aatattattc agctggtcga tgccggaatg
     8221 aaagtgggaa tgccgaccat ggccgtgact ggcgtgggca aagatatggt gcgcgatcag
     8281 cgttatttct cgctcgcgac tcgaatcgcc gctgaaatgg gggcgcaaat tatcaaaacc
     8341 tattatgtcg aaaaaggttt tgaacggatt gttgccggat gtccggtacc cattgttatt
     8401 gctggcggta aaaaattacc ggagcgcgag gcgctggaaa tgtgctggca ggctatcgat
     8461 cagggcgctt ctggtgtgga tatggggcgt aatattttcc agtctgacca tccggtggcg
     8521 atgatgaaag ccgtacaggc ggtggttcac cataacgaaa cggctgatcg ggcatatgaa
     8581 ctctatctga gtgaaaaaca gtaactgcgg atttaaggag aagaattatg cacgtcacac
     8641 tggttgaaat taacgttcat gaagacaagg ttgacgagtt tatcgaagtt tttcgccaga
     8701 accacctggg ctctgtacag gaagaaggca atttgcgctt cgatgtctta caggacccgg
     8761 aagtgaattc gcgcttttat atctacgaag cctataaaga tgaagacgca gtggcgttcc
     8821 ataaaaccac gccccactac aaaacctgtg tcgcgaaact ggaatcttta atgaccgggc
     8881 cgcgtaaaaa acgtctgttc aatggtttga tgccgtgagg cgaatttatc aattttatct
     8941 acaattgggg taacgcgctg acgggagtaa aaaaatgtct gactggaacc cctctttata
     9001 tttgcacttt tccgctgaac gatcgcgtcc ggcggtggag ctgcttgcca gagtgccgct
     9061 ggaaaatgtc gaatatgttg ccgatcttgg ctgtggccca ggtaacagca ccgcccttct
     9121 acaacaacgt tggcctgcgg ccaggataac aggcatcgac tcgtctccgg cgatgattgc
     9181 tgaagcgcgc agtgctttgc cagactgcca gttcgtggaa gcagacatcc gcaactggca
     9241 accggtacag gcactcgatc tgatttttgc taatgcctca ctgcaatggc tgcccgacca
     9301 ctacgaattg tttcctcatc tggtttcttt acttaatccg cagggcgtgc tggcagtaca
     9361 gatgccagat aactggctgg agccgaccca tgtgctcatg cgcgaagttg cctgggaaca
     9421 aaactacccg gatcgcgggc gtgagccgtt ggctggcgtt catgcttact acgatatttt
     9481 gagcgaagcc ggatgtgagg tcgatatctg gcgaaccacc tactatcacc agatgccgtc
     9541 acaccaggcg attatcgatt gggtgactgc cactggatta cgtccgtggt tacaggatct
     9601 gaccgagagc gaacagcagc tttttcttaa gcgctaccat cagatgctgg aagagcagta
     9661 tccactgcaa gagaacggac agatactgct ggcatttccg cgtctgttta ttgttgcccg
     9721 gcgtatggag taaatatcac gtcagctggt aatgacgatc gggaagaatt tttgctggaa
     9781 tttcggcttc atcgttcatc tgtaacaggt caatttcaat agcgttgcag atggcatcca
     9841 gtggtaaatc attgttttca gtaccgaacg gatcttccag ttcttccgcc agacaatcca
     9901 gcgaaataaa agtgtaggaa atcagcacag agataaaagg cgtcatgtaa tgcaggtcca
     9961 cgaccagcgc gaacggcagc atgatacaaa acagataaac ggtacgatgc aaaatcaggg
    10021 tgtaggcaaa gggaattggc gtataggcaa tgcgctcgca tcctgccagg accgctgaaa
    10081 tatcattaag ccgatcgttg aggctaataa acaggatatc tgaaagctgt ccattgcggc
    10141 gctgaaccgc caaccattct cccattatta acaagatacg gttagctgga gagttcgaag
    10201 ccagtacacg ctgaagatct ttagtcttga gataatgagc cagcacttcc gcctgtggct
    10261 gtttgcgtaa tgtcatgcgt aaacagtggg cgaaagcgat ttgcagccgg gcaaactccc
    10321 ttacacttgc cgaatccggc aatgtcgttt ttacctcgcg cagtaacgac cgtgaggcaa
    10381 tcatcaactg cccccaaagt tttcgcgctt caacgtaacg ggcgtacccg gcattattac
    10441 gaaaaccaag aaaaatggcg atggcgacac cgagaatgct gaacggtgcg agggtgaatt
    10501 tgatgcccag atgcgtgtac cagggcagca tgaaaataac agcgatagaa aagagaaaat
    10561 tgagtagtaa gcgcgaggat atcttggata atactgagcc gtgccagaca aaaatacggc
    10621 gcagccagtg ttgttgtgga cgaacaatca tggttatctt caggcgtgga aaagtcgccc
    10681 tattaaacgt gattacgatc acattctcaa gacgctactt acaaattacc tacaagctta
    10741 caacattagc aggcgctgca tgtggcacct gttaatgata aaggcatata ggatgttgta
    10801 actaatatgg tgaactaaga aacccggtcg aaaccgggtt cagaagtaac ggtgttatta
    10861 gcacaacgga cgtacagctt cgcgcatccc tttttcgaga atcgcatcca ggtcattagc
    10921 aacctgctcg accagaccag gcacttgcgt caggtcctgc tcccagtggt ctttttctgc
    10981 caaaacaatc gctaccagtt cctgggtgcc gataacacgg tcacgatgct ggctccagag
    11041 ttgctgataa cgttccagcc agtgtgcatc gtcctgtacc ggatatgttt cgccgttacg
    11101 ctcaccacga tagaacgcaa tcaatgccgc taatgcgaaa gtaaggcgcg ccggaagtgt
    11161 gccgtttgcc ttctgccctg ccagcagctg tggcaggatg cgggtgcgga acttggtcat
    11221 accgttgagc gcgatagaca gcagctgatg cttaatgtac gggttacgga aacgcccggt
    11281 gactgcactg gcgaaagatt ccagttcatc acgaggcaaa tccagtaccg gaataatttc
    11341 ttcgtagata gctttttcaa cgaatgcgca aatttcagca tcgttcatcg cttcacctac
    11401 ggtatccagc cctgcctgga acgccaccgg caccagcgcg gtgtgcgcac cgttgaggat
    11461 tgccactttg cgttctttgt acggtttaat atcgtcaaca atcagcacgt tgagcggata
    11521 tttgtccaga cgcagttcag tcgctaagga tttcggtccc tgaatcacaa acaggtaaaa
    11581 gtgttcagcg gtgtcgagaa aaccatcgtg ataacccagt tcttcttcca gtttagccac
    11641 ttcatcgcgc ggataaccgg taacgatacg gtccaccagc gtagaacaga agctgttagc
    11701 ctgatccagc cattgaataa atgcttctgg cagtgcccac tcttgcgcat agcgcagcac
    11761 cagttcacgc aacgcgtcgc cattgtagtc aatcaactca cacggaatga tgatccaacc
    11821 tttatccagc gcaccgttga aatggctaaa gcgttcgaac agcagacggg tcagttttgc
    11881 cggatagctt accgctggcg cgtcatcgaa tttatcgccc gcatggtagc tgatacccgc
    11941 ttcggtggtg ttagagaaaa caaagcgcat ttccgggttg tgcgccagtt tcaggaattc
    12001 atcgtattca ctgtagacgc tgatttcacg attaaccgag cgaatcagac gcgcgtcgct
    12061 gaccgcttcc cccttctcat tcaggccacg gataatggtg gtgtacagac catcctgcgt
    12121 gctcagtgac ggcgggaatg aagtttcaat cggacgaaca acgaccacac cagaattcag
    12181 atcggtgtgc tcattcagga gatcgatttg ccagtcaaca aaggcgcgca ggaagttacc
    12241 ttcaccaaac tgaatgatac gttctggata ctgtgcaccg ggaaaatcgc gacgatttag
    12301 tgttttcaca atgggttccc ttctgattag tcatacaacc tgtttgaatt ggtacgacag
    12361 gttagcaaac tttaatacgc cgaacccctg ttttgatcaa ctcctgatga ttaatgagca
    12421 gttttatgag aaaagtgtgg cgcggatcat ggtttaatcg aggaaatacg ccttttcctg
    12481 gatcataaag tggtagaaca cattgcattc aaatcgcgcg gaatgaataa agatgtcaga
    12541 caacttcctc accgtaacgc atagtgctgg tacggttgcg cccatctttc ttcgagcgat
    12601 acagacacgt atcggcttcg accatcaatt tattaaagtc atcggtcagc gttcggtacg
    12661 atgcgcgacc actaccgacg ccaatactta ccgtgagata aagcgttttt tgttgccagg
    12721 tgaatggttg cagttcaacg cctttacgga ttttttccgc cattagcaga ccatcgacag
    12781 gattcaccga cggcactgca acagcaaatt cttcgccgcc cattcgcgcc accagcccct
    12841 tatcaccgac aatcttctga atatgccggg caaacacgct taacacttta tcgccacatt
    12901 catgtccata gttatcgtta atgcttttga aatagtcgat atcaagcagc atgacagtca
    12961 gatgttgtgt ctgtttcagc gatagacttt tcagcgcctc ataaagaccg gaccgtgagt
    13021 aaacctgagt cagaaaatca aagtcggctc gcagcgcaac ttgcttcatt agcgaattga
    13081 tcgctgccac gctaaaagaa accataattg ggcatatcgc catcgtggca ataccgagac
    13141 gtgcggagaa catttccgga atggagaacg gcgaaccgac cgagatatca atcaccgaat
    13201 ttgccaccag tacgatttcc accgcaccgg tgacaaaggt caacagacat gttacctgcg
    13261 gcgtatagcg cactgcacac cagattaatg caggcagcgg gaacgccaga ctccccgctc
    13321 caccaatgac taccgaggca ataaccgaca caataagcgc gatggcgggc atcatctgtt
    13381 ctgctttaaa gcgcggcagc actccaggaa tagccaacgt cagcatacaa ggcacgatca
    13441 acacgcccgt tgagaattgc tcactgaacc agtcggcaag caaaggccag aaatccagac
    13501 tatcaatact gaccgaacca atcgccccga caatagcgca taataatgcg gcaatcagac
    13561 agtaattaaa tagccgtaag gcacttactg gctcatactt atttttcccc agacgcttat
    13621 cccgcacgac cagtaaggcg acggtaacaa taaacatcat attggagaaa ttgatagcca
    13681 gtgaaaccag tccccattcg gtggttatgg catcataaac cagcatcgcc acataactga
    13741 tcgcatagta atgcagtcga ttaagccaga catagcgggc aaacaccccc gccattacgc
    13801 cattcagcgg ccagaaaaga gaaagttcgt gaaccagccg taactctgca ccaataaaat
    13861 agaacagcgt ggttagcgca aaaatagcga tgctattacg tagcagatga ccttcctgga
    13921 acaaacggaa agttgaaatg gggtgtacat gcattaatta tctgtccata caattgcggg
    13981 tggcaattat ctcaacgtaa taagtaaatt ctcataaagg atagcgtgtt cgctaacagc
    14041 ggcggcaaat aaaggtaccc tgggaatgct attttatcgt tttccgcaat tctcatggct
    14101 gattcatctg tacaaccagc cagtgataga ttaccgccac gatataacgt tgttgttctt
    14161 cgcttaacga aacaccctgc ggaatgttat gccacttagc cagacaaccg cgacagcagg
    14221 tcgcggtggc gtgctgagcg ataaacaccg gatgcccgcg catgggggtt tgcttaccgt
    14281 cattagccgg taatgccgga gcaagacgtt tagcgacaaa atccgccgca tgttgttcga
    14341 tgactggcgc gcctttctcc aggcaatact gacgctcttt catgcccaga cgaaagcgag
    14401 agcgaaattt tgaacgggat aaacgcgcga agagtggatc gagagactgc attaataaac
    14461 cgaacgccct aactgtttcg tcaattgttc aaggacggca atacccgcaa gcgagttacc
    14521 tgcatcatcc agttccggac tccagacagc gatggccatt tcatgcggaa caatcgccac
    14581 aataccgcca ccaacgccag atttcgccgg tagccccacc cgccaggcaa actcccccgc
    14641 gttctggtac ataccactgg tcgccatcag cgcgttaatt tgccgcgcct gcattggcgt
    14701 caccactggt tcatcaatat gaatagcttt cccctgatta gccagaaaga caaacgtccg
    14761 ggccagctct acacagctca ttttcagagc gcagtaatga aagtagtttt gcagaacggt
    14821 tgtcacgtca tgatggaaat tgccaaacga cttcatcagc caggcgatag ccgcatttcg
    14881 cgcggaatgt tcaaattcgg aacgcgctac caccgtatcg taggaaatat cagacacacc
    14941 gcttaagccg cgcacgactt ccagcatacg ttgccgtggt gcgcttaatc gcccttgcaa
    15001 catatcgcag accaccagcg caccggcatt aatgaacgga ttacgcggta taccctgctc
    15061 catttccagt tgcactaagg aattgaacgg tgatccagac ggatctttgc cgacgcgttg
    15121 ccagatttcc tcttcggagt aatgacgcat ggcgacaacg agactcagca ctttggaaat
    15181 agactgaatg gaaaaacgtt cttgcgcgtc tccggcctga aaaagctgtc cgtcaacggt
    15241 acagatagca atccccaatc gggaaccgtc tactgtagcc agcgccggaa tataatccgc
    15301 gactttaccc tgaccaatga gcggccgcac ttgccgcaag atgttttcta aaattgcatt
    15361 atccatggcg actgccactt tctactcctg gaccgcaggt ctgaaaagac ctgcgagtat
    15421 atcagagctg aatatgtcgc gtcagatccg gtctttccac accgtctgga tattacagaa
    15481 ttcgtgtaag ccgaaatggg aaagctcacg accaaagcca ctctttttca cgccaccaaa
    15541 ggccactcgc gcgtcgctgg cacaataacc attgataaac accccaccgc attccagacg
    15601 tgccgccatc tgtctggcct gtgtttcgtc agtggtaaaa atggtcgctg aaaggccgaa
    15661 ctcactatca ttagccagtt ccagtgcatg ttctgcatct ttcgcaatgg tgattgccgc
    15721 aacggggcca aacatttctt cccgaaacgc ggtcatttct ggggtaacat tcgccagaac
    15781 cgttggcgga tagtagttac ctgccccagc catcttttcc ccgcccagta acaaacgcgc
    15841 accctgcgcc agggttttct ccacctgatg atgcagctca tcacgtaaat caaaacgagc
    15901 cattggtccg agagcgttct cttcgtcacg gggatcgccc attttcaagg ctgccgcagc
    15961 tgccacaaaa cgttcggtaa atgccgaagc aattccctct tcgataataa agcgttttgc
    16021 cgctgcacat acctgtccgg tattctgata acgtccggct accgccgctt tcaccgccag
    16081 ttccagatcg gcatcgttaa gcacaataaa cggatccgaa ccgcccagtt ccagtacgca
    16141 ttttttcagt gccgctccag cctgtgcgcc aatagccgct cccgcacgaa cacttccggt
    16201 caccgtgaca gcagcaatgc gcgagtcttt aatcatctga ctgacaccgt cgttgtcggc
    16261 attcagccag ccatatacgc cttgtgggat acccgcatct ttaaacacct gggcaatgag
    16321 ctgtgcacag cccatcacat tcggcgcatg tttaagtaag tagccgttac ctgcaagaat
    16381 gatgggaaca gcgccacgca tcacctgcca taacggaaaa ttccacggca taatcgccag
    16441 aatcgtcccc aacggtcgat actcaataac cgcctgctga ttttccacca gcgtaggttc
    16501 cgccttcagc attgccggac catgttctgc ataccagtca cacaaattcg ccgatttcgc
    16561 cacttcagcg cgcgcctggt tgattggttt gcccatttcg cgggtgatca tttgcgccat
    16621 ttcttcgcta cgagcgcgca gagccttacc gatatcacgc agtttttcag cacgataatc
    16681 tatatttgtc tcgcgccagt cgcgaaagcc tgctgccgcc agctgaagtg cgttttcgat
    16741 atcgtcagcg ccagcccacg gcagcacaga aagttgttca cccgtggcag gatttatcga
    16801 aattgcatga gttgccggag taatggtcat cggggtatct cctttatgag tcatggtatg
    16861 aagatacgca gatttactct tgctttaaaa tgaataatat taagccactt attcacgaat
    16921 cgagaatgct atggatctga cccaactgga gatgttcaac gcggttgccg aagctggcag
    16981 cataacccag gctgcagcaa aagtgcatcg cgtgccgtcg aatctcacta cccgtctgcg
    17041 ccagctggaa acagaactgg gggttgatct gtttattcgc gagaatcagc gtttacgtct
    17101 ctctcctgcc gggcataact ttttacgcta tagccaacaa attctcgcgt tagtggatga
    17161 agcgcggagc gttgtcgctg gcgatgagcc gcaaggttta ttttctcttg gttcgctgga
    17221 aagcaccgct gcagtgcgca ttccagccac gctggcggaa ttcaaccgtc gttatcccaa
    17281 aattcagttt tcactttcca ccggcccttc cggcactatg ctggatggtg tactggaggg
    17341 aaaactgaat gcggcgttta ttgatggacc cattaaccat actgccatcg acgggatacc
    17401 ggtataccgc gaggaactga tgatcgtcac gccacaagga tatgcgccag taacccgtgc
    17461 cagtcaggtt aatggcagta acatttatgc cttccgcgcc aattgttcgt atcgtcgcca
    17521 cttcgagagc tggtttcatg ctgacggtgc cgctccggga actatccatg agatggagtc
    17581 ttatcacgga atgttggcct gtgtgatcgc aggagcaggc attgcgctta ttccgcgctc
    17641 tatgctggaa agtatgccgg ggcatcacca ggttgaagcg tggccgttag ctgagcaatg
    17701 gcgttggtta acaacctggc tggtctggcg tcgtggtgcg aaaacacgtc cgctcgaggc
    17761 atttattcaa ctgctggatg tgcctgactc ggcaagacag ggatatcaat gagctatttt
    17821 tgatagttct tgcggttaat atgctctata tagtgatgtt ccgatgactt atgactatat
    17881 ggggcaaata tggttacgcc agtaagcatc agcaattaca tatctcttcc tgatgatttt
    17941 cccgtacgta atattgcacc gcaggtaaaa gaagttttaa aggattttat tgatgcactt
    18001 agtacaataa tatgtaatga agagtggcgc acgtctttaa acatcaactc agccacaaaa
    18061 aaga
//
LOCUS       DAPHKZ010000091        18037 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.091, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000091 DAPHKZ010000000
VERSION     DAPHKZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18037
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.091"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(302..1330)
                     /gene="epmB"
                     /locus_tag="RH288_003215"
     CDS             complement(302..1330)
                     /gene="epmB"
                     /locus_tag="RH288_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HDV4032246.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQDEFVVASGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITDALVERFSHSTL
                     QILLVNHINHANEIDETFRQAMAKLRRVGVTLLNQSVLLRDVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
     gene            1372..1938
                     /gene="efp"
                     /locus_tag="RH288_003216"
     CDS             1372..1938
                     /gene="efp"
                     /locus_tag="RH288_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDV4032247.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            1990..2115
                     /gene="ecnA"
                     /locus_tag="RH288_003217"
     CDS             1990..2115
                     /gene="ecnA"
                     /locus_tag="RH288_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HDV4032248.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            2226..2372
                     /gene="ecnB"
                     /locus_tag="RH288_003218"
     CDS             2226..2372
                     /gene="ecnB"
                     /locus_tag="RH288_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HDV4032249.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            2554..2871
                     /gene="sugE"
                     /locus_tag="RH288_003219"
     CDS             2554..2871
                     /gene="sugE"
                     /locus_tag="RH288_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDV4032250.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(2868..3401)
                     /gene="blc"
                     /locus_tag="RH288_003220"
     CDS             complement(2868..3401)
                     /gene="blc"
                     /locus_tag="RH288_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HDV4032251.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDREMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(3490..4623)
                     /locus_tag="RH288_003221"
     CDS             complement(3490..4623)
                     /locus_tag="RH288_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDV4032252.1"
                     /translation="MFKTTLCALLITASCSTFAAPQKINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPATKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAETYGVKSTIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSGNKIALAARPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNALQ"
     gene            complement(4686..5045)
                     /gene="frdD"
                     /locus_tag="RH288_003222"
     CDS             complement(4686..5045)
                     /gene="frdD"
                     /locus_tag="RH288_003222"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDV4032253.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            complement(5056..5451)
                     /gene="frdC"
                     /locus_tag="RH288_003223"
     CDS             complement(5056..5451)
                     /gene="frdC"
                     /locus_tag="RH288_003223"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDV4032254.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            complement(5462..6196)
                     /gene="frdB"
                     /locus_tag="RH288_003224"
     CDS             complement(5462..6196)
                     /gene="frdB"
                     /locus_tag="RH288_003224"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HDV4032255.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            complement(6189..7997)
                     /gene="frdA"
                     /locus_tag="RH288_003225"
     CDS             complement(6189..7997)
                     /gene="frdA"
                     /locus_tag="RH288_003225"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HDV4032256.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERSATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            8322..9299
                     /gene="epmA"
                     /locus_tag="RH288_003226"
     CDS             8322..9299
                     /gene="epmA"
                     /locus_tag="RH288_003226"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HDV4032257.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            9518..11020
                     /gene="yjeM"
                     /locus_tag="RH288_003227"
     CDS             9518..11020
                     /gene="yjeM"
                     /locus_tag="RH288_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HDV4032258.1"
                     /translation="MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGMTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTHLSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRVAKNPQWAVE"
     gene            11072..11386
                     /locus_tag="RH288_003228"
     CDS             11072..11386
                     /locus_tag="RH288_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032259.1"
                     /translation="MDDTSRDPAITEDEIRALQFSAGDVAEIEQTILSFVDACHTRKV
                     AMVVGSTINTLKDRDGKRWGNLPDIYCAYLIRCLVFRGELVGYGDLFRMRYSEIKRPV
                     TL"
     gene            11383..11697
                     /locus_tag="RH288_003229"
     CDS             11383..11697
                     /locus_tag="RH288_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeO family protein"
                     /protein_id="HDV4032260.1"
                     /translation="MSARMFVLCCIWFIVAFLWITITSALDKEWMIDGRGINNVCDVL
                     MYLEEDDTRDVGVIMTLPLFFPFLWFALWRKKRGWFMYATALAIFGYWLWQFFLRYQF
                     CL"
     gene            complement(11726..15049)
                     /gene="mscM"
                     /locus_tag="RH288_003230"
     CDS             complement(11726..15049)
                     /gene="mscM"
                     /locus_tag="RH288_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HDV4032261.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPE
                     VVEALQSALNALEERKGSLERIKQYQQVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     TDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQAASQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(15071..16039)
                     /gene="psd"
                     /locus_tag="RH288_003231"
     CDS             complement(15071..16039)
                     /gene="psd"
                     /locus_tag="RH288_003231"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HDV4032262.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEED
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            complement(16136..17188)
                     /gene="rsgA"
                     /locus_tag="RH288_003232"
     CDS             complement(16136..17188)
                     /gene="rsgA"
                     /locus_tag="RH288_003232"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418585.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HDV4032263.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDISDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            17283..17828
                     /gene="orn"
                     /locus_tag="RH288_003233"
     CDS             17283..17828
                     /gene="orn"
                     /locus_tag="RH288_003233"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HDV4032264.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
BASE COUNT         4150 a         4629 c         4746 g         4512 t
ORIGIN      
        1 taaatagccg tgctcactct atataaacag aaaagaaagg ttaattattg gtgttagcta
       61 tataaaaagt aacaacagca atgcatatga ataattaaag gttatgcaac gtgcaaagat
      121 taaatttctc agtttaatga caggttgctg tacttgcgtt tgttgctctt gccggatgcg
      181 gcgtaaacgc cttatccggc ctacagttca ttgcaaatcc attcaatttc aatgcatgat
      241 gtaggcctga taagcgtagc gcatcaggca attttaatgt ttaacttccc tgtttaatca
      301 gttactgctg gcgtagctgg agatccagcg gcgttttgct gggttcgccg ccaatttctc
      361 gcgccagttt cggcaccaga tatcccgaca ccaatgtcag caactcacgc ataatctgcc
      421 gtgcttcgtc atcactcacc ataaaatgcg ccgcgccctg tactttatcg agcacatgca
      481 ggtaatacgg catcacgccg gcatcgaaca acgcattact caggtttgcc agcgtttgtg
      541 cgttatcgtt cacatcacgt aacagaacgc tctggttcag caaagtaacg cctacccggc
      601 gcaacttagc catcgcctga cggaatgttt catctatctc attggcatgg ttgatgtgat
      661 tcaccagcaa gatttgcagc gtagaatgtg aaaagcgttc aaccagcgca tctgtgatgc
      721 gtgccgggat cacaatcggc agacggctgt gaatccgcag acgtttgata tgcgggatgg
      781 cttccagttg tgtgagcaac cagtccagct cgtgatcttt cgccatcagc ggatcgccgc
      841 cagagaaaat catctcgtcc agttccggat gcgcagcaac atactcaagt gcagtctgcc
      901 agttacgctt gttgccctga ttttcggcat aggggaagtg gcgacggaag caatagcggc
      961 aatttaccgc gcagccgcct ttgaccagca aaagcgcccg gttgtggtat ttatgcaaca
     1021 aaccaggcac tacgctgtgc tgttcttcca gtgggtcggt ggagaatccg gacgcgacga
     1081 caaactcatc ttgcgaggta agtacctgac gcaaaagagg atcgtccgga ttgcctttct
     1141 ccatgcgatc gataaatgag cggggcacac gcagggcaaa cagctttttg gcgctgcgtc
     1201 cggccaacag tttttcgtcc gcgtctatat tcaaaagacg cagaagttca tcaggatcgg
     1261 tcacaacatc ggcaagttgc gttaaccaat cttctctgga tggggtattt agggttacaa
     1321 tatgcgccat tttgtggctt agctaccaat taacaaattt cagagggcct tatggcaacg
     1381 tactatagca acgattttcg tgctggtctt aaaatcatgt tagacggcga accttacgcg
     1441 gttgaagcga gtgaattcgt aaaaccgggt aaaggccagg catttgctcg cgttaaactg
     1501 cgtcgtctgc tgaccggtac tcgcgtagaa aaaaccttca aatctactga ttccgctgaa
     1561 ggcgctgatg ttgtcgatat gaacctgact tacctgtaca acgacggtga gttctggcac
     1621 ttcatgaaca acgaaacttt cgagcagctg tctgctgatg caaaagcaat tggcgataac
     1681 gctaaatggc tgctggatca ggcagagtgt atcgtaactc tgtggaatgg tcagccgatc
     1741 tccgttactc cgccgaactt cgttgaactg gaaatcgttg ataccgatcc gggcctgaaa
     1801 ggtgataccg caggtactgg cggcaaaccg gctaccctgt ctactggcgc tgtggttaag
     1861 gttccgctgt tcgtacaaat cggcgaagtc atcaaagtgg atacccgctc tggtgaatac
     1921 gtctctcgcg tgaagtaatg cggttgtggt gcggcctgca ggctgcacca tcacttattc
     1981 aggtcagaga tgatgaaacg ccttatcgtt cttgttttgc ttgccagcac gctgctcacg
     2041 ggctgtaaca ccgctcgcgg tttcggcgaa gacatcaaac atctcggcaa ctccatctct
     2101 cgcgctgcca gctaattttt cttctcttcc gaaaaatcat cagatttccg tcatttttgg
     2161 cgatgttgtc tattattaat ttgctatagg caaacataaa taacattacc taaaaggaag
     2221 acgttatggt gaagaagaca attgcagcga tcttttctgt tctggtgctt tcaacagtat
     2281 taactgcctg caacaccacg cgtggcgttg gtgaagacat ttctgatggc ggtaacgcga
     2341 tttctggcgc agcaacgaaa gcgcagcaat agcaataagc aataacggta cgacagctgt
     2401 gtcgtgccgt ttgttttttc tgcgatagtc actaaggtaa tagttgaaat tcccctgcca
     2461 cctggcaaaa tatccgttca accatcagct ttgcaggacg acctgcaaac gcgtcttttc
     2521 accggggacg gccccaattc tccggagcct gatatgtcct ggattatctt agttattgct
     2581 ggtctgctgg aagtggtatg ggccgttggc ctgaaatata cccacggctt tagtcgtttg
     2641 acgccgagtg ttattaccgt gacggcgatg attgtcagta tggcgctact tgcctgggcg
     2701 atgaaatcgt taccagtagg gacggcttat gccgtgtgga cgggtattgg cgcagtcggc
     2761 gcggctatca ccggcattgt actgctcggt gagtccgcta acccgatgcg cctggcgagt
     2821 ctggcgttaa tcgtattggg gattattggt ctgaaactca gcactcacta actaccgggc
     2881 tgctgtaccc aaataaactt actgacatca aacccttccc gggtcgcgac tgccagcatc
     2941 tcctgtttca cttcgtcaga aatggttggc gtgcgggaga gtatccacag gtagtcgcgg
     3001 tccgggccgc aaaccagcgc atggcggtat tcccgatcaa gtgcaatgac gttataaccg
     3061 ccatagaaag gaccaaagaa tgacactttc agcgcagcgc gtgttggtgc gccggtaaag
     3121 tacgctttcc cttcactctg ctgccacatt tctctgtcag ggttatagcc tttattgatg
     3181 acattcaggc cgccgtcatc acgcagactg tatgttgcgg tgactttttc cagtccacgt
     3241 tcaaaacggt gatcaaaacg ggcaatctca taccaggtac cgagatagcg tttagcgtcg
     3301 aaattattca ctactgtcac gccacgcggc ggcgtaggag aactgcaggc aacgaccaga
     3361 aatgcagctg tcgctgcggc aacgagaggg agcaggcgca taaatgtttc cttactggtt
     3421 tttttctaag tgtagatgac agcaaggaaa agcgcagaaa aggtccgaaa attcggaccc
     3481 gatgaaattt tactgtagag cgttgagaat ctgccaggcg gcggtgactc tcgctggatt
     3541 gggatagttt ttgttagcca gcatcactat acccagctct ttttctggaa taaacgcgac
     3601 atagctacca aatccgccgg ttgcccctgt tttatgtacc catgatgcgc gtactgcagg
     3661 agttgggggc gtaatcgctt ttacggggcg tgctgccagt gcaattttat tgccactgcc
     3721 gttaatgatg ctgtcaggat ttaccggcca gtccagcatt tcccagccca ggccctgata
     3781 catatcgccg gtttgccagt agcgagattg tgccagttgt atcccttgct gaagtgtttt
     3841 gtcgttgata tcacggggat tcatattgct tcgtacccag caggccatat cttcaatggt
     3901 cgacttcaca ccataagttt cagcatctaa cgcccctggc gaaacatgaa ctgccttgcc
     3961 ttcgcgatat ccccaggcgt aattcttttc ttctgcgggc ggtacattaa tccacgtatg
     4021 gttgagtttg agtggctgga agacacgtgt ttgcatcgcc tgctcaaaac tcaaaccaga
     4081 cggcttcaca gccagtgcgc cgaacaaacc gatactggag ttggcataca gacgttgtgt
     4141 tcctggagcc catgcaggct gccagttttg atagaagcgc agcaagtcgc ttgaggattt
     4201 cacctcatcc ggcacctgca atggcaggcc gccagcggtg taggttgcga gatgtaatag
     4261 tgtgatcccg ttccactgtt tagcggtaag ttcaggccag tattttgttg cgggatcgct
     4321 taacttgatt tcccctcgag caatagcgtc gccaccaagc acgcccgtaa atgttttgct
     4381 gaccgaacct aactcaaaca acgtttgctg tgtgacgggc tgctttttgg cgatgtccgc
     4441 atagccccag gtaaagtaat aaggtttacc ctgataaatt accgccaccg ccataccggg
     4501 gatcttttgt tgctctataa gcggggtaat tgtgcgatgc acaatatcgt tgattttttg
     4561 gggggcagca aatgtggagc aagaggcggt aattaataag gcgcagagcg tcgttttgaa
     4621 catagggtct ggtttccata caaaacggcc cgccataggc gggccggatt tacattggcg
     4681 atgcgttaga ttgtaacgac accaatcagc gtgacaactg tcaggatagc agccagaccg
     4741 tagaaaaccc atttgcccgc aggtacgtgg attttcagat cgtgcatcgc gtggtgcata
     4801 cggtgtaaac cacaccacag cggcagaacg atcatcagga acaggaatac gcgaccaatg
     4861 aagctctgcg cgaacgccag aacgcgctcg tagctcagtg catcacccgg aaacagcccc
     4921 agcggcagca gaatacccac cagcaggatc atcaccggcg caataattgc gctccacata
     4981 ccaccggccc cgaagaggcc ccagaatacc ggttcgtcag aacgctttgg atttggattg
     5041 atcatctcag gctccttacc agtacagggc aacaaacagg attacgatgg tggcaaccac
     5101 agttaccgcc cagagacttt tgataattgg ctctggaccc attttttcgt cttttacaat
     5161 gatattggcc gctttcggtg ccagttcaaa ccaggttttg gtatgcagca gagctgccgc
     5221 cagagtgatc aggttaatga tcacaataac cgggttttgt aaaaagtcga cgaatcccgc
     5281 ccaggcttcc gggccatttt tcagggcaaa cagcccgaaa atcagttcaa tgctgaacca
     5341 cacagccgga accgccgtgc cttcgcgcag catgtaaaag cgataaaacg gcaatttttt
     5401 ccaccaggtg gacgtcattg gccgtacata cggtttacgt ttagtcgtca tgttgcactc
     5461 cttagcgtgg tttcagggtc gcgataagaa agtctttcga actttctact ttgccctgct
     5521 gaatggccgc agccggatcg acgtgtttcg ggcagacttc ggagcaatag cccacgaaag
     5581 tacagctcca tacgccgttc tggctgttca actgcgccat acgctccttc ttaccgtggt
     5641 cgcggctatc ttcgttataa cgatgcgcca gcgtaatggc agccggaccg atgaactctg
     5701 ggttcaggcc aaactgcggg cacgcggcgt agcacagacc acagttgatg caaccggaga
     5761 actggtgata cttcgccatc tgcgccgggg tctggatgtt agtaccctga tccgcggtgc
     5821 gggagttgcc gatgatgtac ggtttgatcg cttccagact ttcgatgaag tgggtcatat
     5881 cgaccaccag atcgcgttca atcgggaagt tagctaacgc ttcaaccttc ataccgtcgg
     5941 tgtaatcacg caggaaggtt ttacatgcca gttttggcac gttgttaacc atcatgccgc
     6001 aggaaccaca aatcgccata cggcaggacc agcggtagct caggtccggt gccaggttgt
     6061 ctttgatgta gcccagcgca tccagtaatg aggtagttgc gtcataaggc acttcataga
     6121 atgcgctatg cggtgcggta tcgacttccg ggttatagcg caccacctca attttcaggt
     6181 ttttcatctc agccattcgc cttctccttc ttattggctg cttccgcctt atcggctgca
     6241 tccgcttcgc caccgtaaac gcgtttagct ggcggcagcg tagtaatctt cacgtcgctg
     6301 tactccaggc gagtcgtgcc atcagcatcg cggaaggcga gggtgtgttt gaggaagttg
     6361 acgtcgtcac gctcggtgca accttcgtcc agacgctggt gtgcgccgcg ggactcttta
     6421 cgtgccattg cggagtgcgc catacattca gcaacgttca gaccgtggcc cagttcaatg
     6481 gtgtagagca ggtcggtgtt gaacacgctg gaggtgtcgg tgatgcgcac gcgcttgaag
     6541 cgttcctgca gttctgccag cttgtcgatg gttttctgca tcagttccgg cgtacggtag
     6601 ataccgcaac cttcttccat tgccaggccc atttcgtcgc ggatcttcgc ccagttttcg
     6661 ccgccatcct ggttaaccag atctttcaga cgttgttcaa cgccagctgc ctgcgcttca
     6721 attgccgctt cgttgccatt accggcagtt gctgaacgct ctgtcgcttg ttcaccggcc
     6781 agacggccga agaccaccag ttccgccagg gagttggagc ccagacggtt tgcaccgtgc
     6841 agaccaacag aggaacattc acccacggcg aacagacctt taatgcgggt ttcacagttc
     6901 tgatcggttt cgataccgcc catggtgtag tgtgcggtcg gacgtaccgg aatcggttct
     6961 ttaaccggat cgacgccaac gtacgctttc gccagttcgc agatgaacgg cagacgttca
     7021 tgcagttttt tctcgccgag gtgacgcagg tcgagataaa ccacatcgcc acgcggcgtg
     7081 gagatggtgt tgcctttacg ccattcgtgc cagaaggcct gagaaacttt gtcgcgtgga
     7141 cccagttcca tatatttgtt tttcggctcg cccagcggag tttccgggcc catgccgtaa
     7201 tcttgcagat aacggtagcc atttttgttg accagaatac cgccttcacc gcggcagcct
     7261 tcggtcatca ggataccgga acctggcaga ccggttgggt gatactgaac gaattccatg
     7321 tcacgcagcg gaacgccgtg gcttagcgcc atacccatac cgtcaccggt aacgatgccg
     7381 ccgttggtgt tgtaacgata aacgcgaccc gcaccgccag tagccataac gaccgcgtta
     7441 gcacggatct gcaccagcgt gccttccatc atgttcattg ctaccaggcc gcgaacatga
     7501 ccatcatcaa ccagaatatc cagcacgaaa tgttcgtcaa aacgctggat ctgcgggaat
     7561 tgcagagagg tctggaacag cgtgtgcagc atatggaagc cggtcttatc ggcggcgaac
     7621 caggtgcgct cgattttcat gccgccgaag cgacgtacgt tgacgctacc atccgggcga
     7681 cggctccatg ggcatcccca cagttccagt tgggtcattt cggttgggca gtggtggacg
     7741 aaataatcca cgacatcctg ctcacacaac cagtcgccac ccgctactgt atcgtgaaag
     7801 tgatattcga agctgtcatg atcctgcgcg acagcggcgg agcccccttc tgcagcaacg
     7861 gtatggctac gcatcgggta tacttttgag attagtgcga tttttgcatt cggatttgcc
     7921 tgcgcggcag caattgcagc acgtaatccc gcgccaccgg cgcctacaat ggcaagatcg
     7981 gcttgaaagg tttgcacgac attcctccag attgttttta tcccacagcc acgtacttca
     8041 gggtaagtac ctgaaagtta cggtctgcga acgctattcc actgctcctt tataggtaca
     8101 acagtatagt ctgatggata agtctgaaat ttgacgagat cgattttttt agtgcgcaag
     8161 agggctaaat tatcactgaa gatgattaat ttaattacta aaccatcaga tcgtgctttt
     8221 tttagtcact gcccaccgct gtttgattcc tgcgtaaaat ttgtctcgcc gtcgcgttgc
     8281 gagtagactt cgtgcccttg tcaaaaactg gagatttaac tatgagcgaa acggcatcct
     8341 ggcagccgag cgcatccatt cctaacttat taaaacgcgc ggcgattatg gcggagatcc
     8401 gtcgtttctt tgccgatcgt ggagtgctgg aggtggagac gccttgtatg agccaggcga
     8461 cggtaaccga tattcatttg gtcccgtttg agacacgttt cgtaggcccc gggcattcgc
     8521 aggggatgaa tctctggtta atgaccagcc cggaatacca tatgaaacgc ctgctggttg
     8581 ccggttgtgg gccggtattc cagctgtgcc gcagcttccg taatgaagag atggggcgtt
     8641 atcacaaccc tgagttcact atgctggagt ggtatcgacc gcactatgat atgtaccggt
     8701 tgatgaacga ggtggacgat ctcttacaac aggtgctgga ctgcccggca gcagaaagcc
     8761 tttcttatca acaagctttc ttgcgttatc tggaaattga cccgctctct gccgacaaaa
     8821 cgcaactgcg ggaagtcgca gcgaaactgg atttgagcaa tgttgctgat accgaagaag
     8881 accgcgacac gctgctacaa ttgctgttta cctttggcgt agagccaaat attggcaaag
     8941 aaaaaccgac ctttgtgtac cactttccag ccagccaggc atcactggcg caaatcagta
     9001 ccgaagatca tcgggtcgct gaacgctttg aggtttatta taaaggtatt gagctggcga
     9061 atggtttcca tgaattgacg gatgcccgtg agcagcaaca acgctttgaa caagataacc
     9121 gtaagcgcgc ggcgcgcggt ttgccgcagc accccattga ccagaatctg attgaagcct
     9181 tgaaagtcgg tatgcctgac tgttccggcg tggcattagg tgttgatcgt ctggtgatgt
     9241 tggcgctggg cgcggagaca ctggctgaag tcatcgcctt tagcgttgac cgggcataat
     9301 tctgaaaaat tactgaatta acagcgaaga atggcgtgat aagcgccatt ctgtagcata
     9361 tgttttcatt tttccgttaa aggccacaat ttaagactgg atatttgata tcatccaggt
     9421 atcaattctg tattggtttt tacgctgcct gctcaatgtt gcgcagtgca gttcagtggg
     9481 cacgtgttat acacgcgctg aaatgaagga tggtttcatg cctcacacga taaaaaagat
     9541 gagtctgata ggactcatat tgatgatctt tacttccgta tttggatttg ccaatagccc
     9601 atcggcttat tacttaatgg gttatagtgc gattcccttt tatatatttt ctgcattgtt
     9661 attctttatt ccattcgcct taatgatggc tgaaatggga gctgcttatc gcaaagaaga
     9721 aggcggtatc tattcctgga tgaataatag tgtcggacca cgttttgcct tcattggtac
     9781 gtttatgtgg ttttcctctt atatcatctg gatggtgagt acctccgcga aagtttgggt
     9841 accgttctca acattcctct atggtagcga catgacccag cactggcgta ttgccggact
     9901 ggagcctacg caggtggttg gtctgctggc tgtggcatgg atgattctgg tcaccgtcgt
     9961 tgcttctaag gggattaata aaattgcccg cattactgcg gtgggcggta ttgcagtaat
    10021 gtgtctgaat ttagtattgc tgttagtaag cattactatt ttgttattaa atggtgggca
    10081 tttcgcgcag gatattaatt tccttgcatc accgaacccg ggttatcagt ccggtctggc
    10141 aatgctatcg tttgtggtat ttgccatttt tgcctatggc ggaattgaag cggttggtgg
    10201 tctggtcgat aaaacggaaa atccagaaaa gaactttgcc aaaggtattg tttttgccgc
    10261 tattgttatt tcaatcggtt attcgctggc aatattttta tggggcgtca gcacaaactg
    10321 gcagcaggta ttaagtaatg gttccgttaa cctcggcaat attacctatg tgctgatgaa
    10381 gagccttggg atgacgctgg gtaatgcact gcatttgtca cctgaagcgt cattgtcgct
    10441 gggcgtatgg tttgcgcgta ttactggact ttcgatgttc ctcgcctata ccggtgcgtt
    10501 ctttacgctt tgctattcac cgttgaaagc catcatccag gggacgccga aagcattgtg
    10561 gccggaaccg atgacgcgcc tgaatgcgat ggggatgccg tctatcgcca tgtggatgca
    10621 gtgcgggttg gttactgtct tcatcctgct ggtttcgttt ggtggcggta ccgcatcggc
    10681 gttctttaac aagctgacgc tgatggcgaa cgtgtctatg acgcttcctt acctgttcct
    10741 cgcgctggct ttcccgttct ttaaagcacg tcaggatctc gacagaccgt ttgtgatttt
    10801 caaaacgcat ttgtcggcaa tgattgcgac agtggttgtc gtactggtgg tgacatttgc
    10861 gaacgtcttc accatcattc aacctgtggt tgaagccgga gactgggaca gcacattgtg
    10921 gatgattggc ggccctgtct tcttctcgct gttagcgatg gcgatttacc agaactattg
    10981 cagcagagtg gcaaaaaatc cgcagtgggc ggtggaataa cccgatgccc tatcgtctac
    11041 ctgacgatag ggcgtaaaga caggaaatgt tatggatgac accagccggg acccggcaat
    11101 aaccgaagat gaaatcaggg cgctgcaatt ttctgccggg gatgtagcgg aaatagagca
    11161 gacgattctc tcttttgtcg atgcctgcca cacccgtaaa gtggcgatgg tggtgggtag
    11221 caccattaac accctcaaag atcgcgatgg taaacggtgg ggaaacctgc cggatattta
    11281 ttgcgcttat cttatccgat gtctggtttt tcgcggggaa ttagtgggat acggcgattt
    11341 gtttcgtatg cgctatagcg aaattaagcg accggttacc ttatgagtgc gcgcatgttt
    11401 gtcttatgct gcatctggtt tattgtggcg ttcctctgga taaccatcac ttccgcgctg
    11461 gacaaagagt ggatgattga tggacgcggg attaacaacg tctgcgatgt gttgatgtat
    11521 ctcgaagaag acgatacccg tgatgttggt gtgataatga cgttaccgct ctttttccct
    11581 tttctctggt tcgctttgtg gcgaaaaaaa cgcggctggt ttatgtacgc caccgcgctg
    11641 gctattttcg gctactggct gtggcagttt tttctgcgct atcagttttg tttgtgagcc
    11701 ggattggttc atccggcaca caaacttaca aacttcccgc ctgacgacct ttgcccgcag
    11761 acgtcagcgt tctccccgtt tgtttaccgt tgaggctttc cagacgcatc tggaagggcg
    11821 ggaatggcat atcgataccg tgggcatgga agccagccag aatcagctgg tggatctcat
    11881 ggcgtagcgg catacggtga cccatctcag cggcgtaaat acgcagctcg aaaatctgaa
    11941 tcccctgttg cagatccacc aggaagactt ccggtgccgg gttgtcgatc accagcgagc
    12001 agcgacgcgc tgcggtgagc aggatttccg tcacttcttc gctattggca tcggcagggg
    12061 ccggtatcgt caacaccacg cgcgtgaccg agtcagagag cgaccagttg ataaactgct
    12121 cggtaataaa cgccttgttc ggcacgatta tctctttacg gtcccagtcg ctgatggtgg
    12181 tggcgcgggt gttaattttc gtcacgctac cggtgagatc gcgaattgtc accgtatcgc
    12241 caatgcgaat cggtttttcg aacaggataa tcagaccaga gataaagttg gcgaaaattt
    12301 cctgcaaacc aaaaccgaga ccaacaccga gcgcggcaac cagccactgc aatttcgacc
    12361 actcaatacc aatcattgag aagccgacca gcccgccaat cagcatcagc agatatttgg
    12421 tgatggtggt gatggcgtaa cccgtacccg gcgttaaatc caggtgctgc aaaatcgcca
    12481 gttccagcag cgcgggcaag ttgcgcacca gctgcgtggt gatgataaac accagaatgg
    12541 caatcagcac cgcaccgagg gtaattggct ccagactttc tacgccctgt accgtggagg
    12601 tgacatccca cagcgaaata ttttcgagga agccgaaagc ggaatggatt tctgaccaca
    12661 gcacaatgac agaaagcagg gcgatcaaca tcaaaattga gcgcaccagc cgcaaggatt
    12721 gcgcactgat ggcatcgaga tcgacttcgc tttcatcgac ttcaattgct ccttccgggc
    12781 tactgtgatg atgcgcttcc tcttcgccac gcgcacgttg cgctaacatc tctgcccggc
    12841 gatgcttcgc ccgatcaaac gccagcctgc ggcgctggat cagcatccag cggcggataa
    12901 cgtgataaac caccagtagc aggaaccaga tggcaaccga ggtttcaagc ctcgctaaca
    12961 gcgcctgtgc cgttgccaga taacccaccg ccgacgccag aatggcaacc aacggcgcgc
    13021 caatcatcat gttccacagc atatggttgg taatgttgtc gccgctgccc tctttgttga
    13081 gatacagcgg aatcccggcc tttttcaggc tgagggtgac caccgccagc gcaccgcaaa
    13141 tgaggataaa gcaaagccgt cccagcgaac cggagaattc acggtcgtcg aggttatcga
    13201 acatcatcag cgccataatc agcggcacaa taagcccgat gctcatcagg tagtagcgca
    13261 tcccacggga aacacgttcg cgcggccagc caaaatgagc gataaacaag ccgttcgggc
    13321 gggcaaaggt ggcgcaaatc atcactaccc acagcagcgg cacggtggcc gttacaccat
    13381 cgccaatcgc gaccgccagc ggataaggcc acgcctcgcg caagccgtaa cccagcgtca
    13441 tccacagcac cggtaacggt gacgcgacga gaatcgacca gaaaagagtg cgcaacgtca
    13501 gccagaagtg atcctgagtc actttgccaa ctttcgccgc cgaacgttca agaaaacggg
    13561 tgaaatagcg gcgcgagtaa atactgcaac cgaccagaat caacgcgcca aacagcggca
    13621 aaattgtctc tttgctggtc agcatcatca cactggcttt gcccaactga ctgaaggtgt
    13681 ccagcgaaat gagacgacgc agatcctggg cgatttccag cggccaggcg atggtcatcg
    13741 ggcgcacgtc agaggtccag aacagatagc ggtgcgttgc ttcgttcacc tctttcagcg
    13801 catcctccag ttgcccgttg gagactttca gcttggtcag ttccaatagt agcgtgtcgc
    13861 caccctgcaa caatgagttc agcaactcac gctgagtgcg cagttgtgct tccagaatac
    13921 ggttttgctc ggcagtcagc ggctgaccgt cggcctgatg aatttgccgt agcagcggct
    13981 gtttattaag cagatcctca taacgtaacc gttgcacacg caactgcgcc atttcggtat
    14041 caagctgttg tggtttcggc atttccggca gccgtgccac ctgcgcccgc agcgcttcgc
    14101 cgagcagatt ggacgatccc agccattgcg actgttcacg cagcgtattc aacgcctgcc
    14161 ggacctgtaa cgtctggctg gcagcctgac gctgttgcga ggcaacgaga tccatccgct
    14221 gcgcctgttg attcaaagcc gccgatagtt cgcggttaat tttgaattgc gcgacgatat
    14281 ctttcggcaa atcggcgctg ttttctgcca gcaattcggt actttccagc gcccgctccg
    14341 cctcaagctg acgttggctg tttaattgat tacgcaaggc ctgcaaatac gcatccagtt
    14401 gctggctctc tttttccgcc agctctgagc gtaagcgcgc taattcctgg cggttattgg
    14461 cagacagctg cgccagctcc agttcatcaa cgagcgcctt aagacgtgca gagtcagact
    14521 gcaacgcgaa attttgtgcc tgattgagcg gagtattgcc ggtaagcgtt cccaggcggc
    14581 gctcgatctc atttaactga cggcgggcgt cggtttgctg ttgcggcagt tgattcagcg
    14641 aatcggcaat ctcgcgggcg cgctcctgct cttgctgggc ctgacggctt ttatccagca
    14701 actggctgct gacctggaga atttcctgat tcagcgcgtc ggtagacatt cccggcgaca
    14761 cgctgcgcgg ctcgtcacgc atgttgttta attgtgcgcg cagagtagcg gagagtttcg
    14821 gataattatc gataacttgc tgatattgtt tgatgcgctc aagggaacct tttcgttcct
    14881 caagcgcatt taaggcagac tggagcgcct ctacgacttc cggctgtgcg ggtttcgccg
    14941 cttttgcctg ctccagttcc tgagtgattt gtttgctatc gggggccgtc gcggcgtacg
    15001 ccccccaact gaggcaccag gccatcagaa aagtgataat caggcgcacg tcagcgtttc
    15061 ctttgatgga ttagacctgg tcttttttgt cgtcaaccaa tgggctggcg tcgtgttctg
    15121 cttcgatctc ttcagcagga agcggggcag gttcagcgtc tggcgtaaca aaggtttcgg
    15181 tagatactgc cagcggctgg ccaattttcg tgacagacag gctttccagt tgctcaacca
    15241 gattcacttt acccggtgca aacaggttga taacggtgga accgagttta aagcgaccca
    15301 tttcctggcc tttcagcagt gccacagaac cgtcgttttc cccggcaggc caggtccagc
    15361 gcttgatgat accttcgcgc ggcggcgtaa tggtgcccgc ccagaccgtc tcaatgctgc
    15421 caacaatcgt cgctccgacc agaatctgcg ccattgggcc aaattcggta tcgaaaaggc
    15481 aaatcacgcg ttcgttacgg gcaaacagat tcggcacgtt ctgagccgtg agatggttaa
    15541 cggagaagag atcgcccggc acgtagatca tctcacgcag aataccgttg cacggcatgt
    15601 gtacgcggtg gtagtcacgc ggggagaggt aagtggtcac aaacgtaccg ttgcggaaca
    15661 ggtccgccat cagatagttg cctgccagca gggcttcgag gctgtagttg tggcctttgg
    15721 cttgcaggat tttatcttct tcgattttac ccaactggct gataacgcca tcggcaggca
    15781 tgaccagtac attcggatcg gtatcgattg ggcgtacttc gtcacgcagc ggacggacaa
    15841 agaattcgtt aaaggtgcgg tagctggcgg tgtccggctt ttgcgcctct ttcatgtcga
    15901 ccttgtagta tttaacgaac agatcgataa ccagttttgt cagccatcct gcccgcttgc
    15961 ttgcgcccca acccgccagg cgagtaagcc atagtttcgg cagaatgtac tgtagcgaaa
    16021 gtttaaatga atttaacaag gtagcctcca ggccattgtt ttgtcgttcc tgatccggcc
    16081 tacatgccgg atcctgaaaa aaaggggacg attctaacga cggttagctt aattgtcagt
    16141 catccgtatc agaaaagttt ttacgcgttt ttacctgcgc catgctttcc agaatacggt
    16201 gatagttttc gaaacgggtt tccgcgattt tcccttcctc aaccgcttcc cggatagcgc
    16261 agcccggatc ggtatcgtgt ttgcaatcgc gatatttaca cagacctaaa tagtcatgga
    16321 attcgacaaa gccctgagtg atttgttccg gctccaggtg ccagaggccg aactcacgca
    16381 ctcctgggga gtcaatcaca tcaccgccgt gcgggaagtg atacagccga gcggcggtcg
    16441 tggtgtgctg accgagcccc gagttgtcag agatatcgtt ggtcaggatc tctttttgca
    16501 gccccagcaa cgcattcagc aggctggatt tgccgacgcc agactgcccg gcaaaaatgc
    16561 tgatgcgccc ggtcaacgcc tcttccagcg gttttagccc atcctgagta tggctggaaa
    16621 ccatcaatac gcgataaccg atattgcggt agatatccat ctgctcgttg acgaacgcca
    16681 tgccttcgtc gtccagcagg tctatcttgt tgagcacaat aatcggctca atctgcaagg
    16741 tttcgcaggc caccaggtaa cggtcgataa tattgagcga cagctccggc aaaatggcgg
    16801 agacaatgac aatctggtcg atgttggcgg caataggttt tacgccgtcg tagaaatccg
    16861 gacgcgtcaa caccgaggta cgctcatgca ccgcttccac gatccctttg acatttacgc
    16921 cttccgccgc cggtttaccc ggacgccaga ctacgcggtc gccggttacc agcgaacgga
    16981 tggtacggcg aatattgcag cggtgaacgt cgccatcggc ggattccaca tcagcgtgca
    17041 taccaaagcg gctgatgacg ataccttcat caggctcgcc aaacagattg tcgtcgtagt
    17101 cgggcttctc cttagacgtt ttaagacgac gctggtgatt ggcgttcacg cggcgctgct
    17161 ggcctttgga gagtttattt ttactcaatc gtacagactc ctggtcgccc ctgatgggca
    17221 aaacatctat gatacacgca attgtggatc aatatagtca ctgtgaatgg gtggaaaata
    17281 gcatgagtgc caatgaaaac aacctgattt ggatcgatct tgagatgacc ggtctggatc
    17341 ccgagcgcga tcgcattatt gagattgcca cgctggtgac cgatgccaac ctgaatattc
    17401 tggcagaagg gccgaccatt gcagtacacc agtctgatga acagctggcg ctgatggatg
    17461 actggaacgt gcgcacccat accgccagcg ggctggtaga gcgcgtgaaa gcgagcacga
    17521 tgggcgatcg ggaagctgaa ctggcaacgc tcgaattttt aaaacagtgg gtgcctgcgg
    17581 gaaaatcgcc gatttgcggt aacagcatcg gtcaggaccg tcgtttcctg tttaaataca
    17641 tgccggagct ggaagcctac ttccactacc gttatctcga tgtcagcacc ctgaaagagc
    17701 tggcgcgccg ctggaagccg gaaattctgg atggttttac caagcagggg acgcatcagg
    17761 cgatggatga tatccgtgaa tcggtggcgg agctggctta ctaccgcgag cattttatca
    17821 agctgtaaaa tttttcctgg tcacgtaagc gccggaatcc acttgcggcg gcgtgatttt
    17881 gacgctaaat tgaacgtctt gctgataatt tcagcacttg agataaaaac gcaaaaaaaa
    17941 cttttttggg gggttgcaga gggaaagatt tctcgtataa tgcgcctccc gtaacgacgc
    18001 agaaatgcga aaattacgaa agcaaaatta agtagta
//
LOCUS       DAPHKZ010000092        17919 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.092, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000092 DAPHKZ010000000
VERSION     DAPHKZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17919
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.092"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..534
                     /locus_tag="RH288_003234"
     CDS             <1..534
                     /locus_tag="RH288_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDV4032265.1"
                     /translation="IFAIFIVAAITCISQPKKTTLRDKAMVNYAFDYLSSPGSLPFTT
                     AATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRAQSKLGWI
                     YLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQKWLKLAA
                     KQHYKNAERLLAGLPAH"
     gene            complement(544..1971)
                     /locus_tag="RH288_003235"
     CDS             complement(544..1971)
                     /locus_tag="RH288_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="HDV4032266.1"
                     /translation="MKNCWKILDIEETTDVDIIRRAYLALLPSFHPETDPQGFKQLRQ
                     AYEEALRIAQSPAKSVWQPEEYEVAEHEILLAFRALLASDSERFLPSAWQRFIQQLNY
                     CSMEEIDELRWSLCTIAMNTAHLSFECVVLLAERLRWLQEENTGEIDEEELESFLYAI
                     AKGNVFNFQTILHLPVAVQNDTIDFYQMFARIWSSHPQWLTLYLAQHRAVIIPDDAKL
                     HRNLLRWYSAGRLDIPELLDYAQSWRETEPDNEDAPYYEYAQRVYCGEGESLLAELCD
                     YWREYPSTQADALMLQWCRQHRVDYYPLLVMMIEARDLVNDQGKPLLYVPGDSARTRF
                     HLYEILSDEKLSALGRSLVEMVLHKGRKPRISLTRDTEHTLWPLYLVAKQLVQACQPT
                     EESLMPIVSRLDAENRCPLEALIIRRLLIQAANFTEKQTVEPEPQPQPMPVDDGGPGC
                     LGIIKIIFYIFIFAGLIGKILHLFG"
     gene            complement(1968..2675)
                     /locus_tag="RH288_003236"
     CDS             complement(1968..2675)
                     /locus_tag="RH288_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HDV4032267.1"
                     /translation="MDMESQKILFALSTPMEIRNECCLPSHSSPKMYLGTCFFDLSSS
                     WGIDDRDDLLRTIHRMIDNGHAARLAGFYHRWFRYSPCEWRDYLAELNEQGQAYAQFV
                     ASTAECCGEGGIKAWDYVRMGFLSRMGVLNNWLSEEESLWIQSRIHLRALRYYSNWRQ
                     YFAGYTFGRQYWQSPEDDHLPLLREFLARKEYDDSGNDMFYQLFASDDAYYPTLSWQP
                     LAYYSACPETLKDMSDL"
     gene            2839..3816
                     /locus_tag="RH288_003237"
     CDS             2839..3816
                     /locus_tag="RH288_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415177.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HDV4032268.1"
                     /translation="MIFTSSCCDNLSIDEIIERAEKGDCEAQYIVGFYYNRDSAIDSP
                     DDEKAFYWLKLAAEQGHCEAQYSLGQKYTEDKSRHKDNEQAIFWLKKAALQGHTFASN
                     ALGWTLDRGEAPNYKEAVVWYQIAAESGMSYAQNNLGWMYRNGNGVAKDYALAFFWYK
                     QAALQGHSDAQNNLADLYEDGKGVAQNKTLAAFWYLKSAQQGNRHAQFQIAWDYNAGE
                     GVDQDYKQAMYWYLKAAAQGSVGAYVNIGYMYKHGQGVEKDYQAAFEWFTKAAECNDA
                     TAWYNLAIMYHYGEGRPVDLRQALDLYRKVQSSGTRDVSQEIRETEDLL"
     gene            complement(3886..4368)
                     /locus_tag="RH288_003238"
     CDS             complement(3886..4368)
                     /locus_tag="RH288_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HDV4032269.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMRVIKESLWQELADITDKTQLEWR
                     EVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
                     "
     gene            4603..7185
                     /gene="leuS"
                     /locus_tag="RH288_003239"
     CDS             4603..7185
                     /gene="leuS"
                     /locus_tag="RH288_003239"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDV4032270.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNP
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDH
                     EAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQY
                     KEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTA
                     KGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     TDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVED
                     STLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            7200..7781
                     /gene="lptE"
                     /locus_tag="RH288_003240"
     CDS             7200..7781
                     /gene="lptE"
                     /locus_tag="RH288_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HDV4032271.1"
                     /translation="MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPN
                     GPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIM
                     TVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLP
                     SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN"
     gene            7781..8812
                     /gene="holA"
                     /locus_tag="RH288_003241"
     CDS             7781..8812
                     /gene="holA"
                     /locus_tag="RH288_003241"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDV4032272.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAA
                     QGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTG
                     LLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
                     ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRGMMGEALNRLSQTQLRQAVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHK
                     PLADVFIDG"
     gene            8814..9455
                     /gene="nadD"
                     /locus_tag="RH288_003242"
     CDS             8814..9455
                     /gene="nadD"
                     /locus_tag="RH288_003242"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDV4032273.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPP
                     HRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPL
                     AFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
                     LHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR"
     gene            9479..10090
                     /locus_tag="RH288_003243"
     CDS             9479..10090
                     /locus_tag="RH288_003243"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HDV4032274.1"
                     /translation="MRLWLIRHGETQANIDGLYSGHAPTPLTARGIEQAQNLHTLLHG
                     VSFDLVLCSELERAQHTARLVLSDRQLPVQIIPELNEMFFGDWEMRHHRDLMQEDAEN
                     YSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEFQHYQNILVVSHQGVLSLLIARL
                     IGMPAEAMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA"
     gene            10350..10667
                     /gene="rsfS"
                     /locus_tag="RH288_003244"
                     /gene_synonym="rsfA"
     CDS             10350..10667
                     /gene="rsfS"
                     /locus_tag="RH288_003244"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDV4032275.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQESRAAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            10671..11138
                     /gene="rlmH"
                     /locus_tag="RH288_003245"
     CDS             10671..11138
                     /gene="rlmH"
                     /locus_tag="RH288_003245"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDV4032276.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            11169..13070
                     /gene="mrdA"
                     /locus_tag="RH288_003246"
     CDS             11169..13070
                     /gene="mrdA"
                     /locus_tag="RH288_003246"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HDV4032277.1"
                     /translation="MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     VRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVT
                     DPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIH
                     SGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAEN
                     PAVAAAEDH"
     gene            13073..14185
                     /gene="mrdB"
                     /locus_tag="RH288_003247"
                     /gene_synonym="rodA"
     CDS             13073..14185
                     /gene="mrdB"
                     /locus_tag="RH288_003247"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HDV4032278.1"
                     /translation="MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTGIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPE
                     SDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            14196..15284
                     /gene="rlpA"
                     /locus_tag="RH288_003248"
     CDS             14196..15284
                     /gene="rlpA"
                     /locus_tag="RH288_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HDV4032279.1"
                     /translation="MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEIS
                     GADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFD
                     PTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
                     NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILP
                     VSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPA
                     MVTPQAVSQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGP
                     FASKAEASTLQQRLQTEAQLQSFITTAQ"
     gene            15423..16634
                     /gene="dacA"
                     /locus_tag="RH288_003249"
     CDS             15423..16634
                     /gene="dacA"
                     /locus_tag="RH288_003249"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HDV4032280.1"
                     /translation="MNTIFSARIMKRLALTTALCTAFISAAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG
                     REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            16744..17007
                     /locus_tag="RH288_003250"
     CDS             16744..17007
                     /locus_tag="RH288_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HDV4032281.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYT
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL"
     gene            17108..17749
                     /gene="lipB"
                     /locus_tag="RH288_003251"
     CDS             17108..17749
                     /gene="lipB"
                     /locus_tag="RH288_003251"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415163.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HDV4032282.1"
                     /translation="MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELV
                     TLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA"
BASE COUNT         4537 a         4489 c         4574 g         4319 t
ORIGIN      
        1 atattcgcaa tttttatagt tgcagcaatt acctgtatta gccaacccaa gaaaacgacg
       61 ttgcgtgata aagccatggt gaattatgcc tttgattatt taagctcacc gggcagtctt
      121 ccattcacca cggcagccac ggagctttcc gcgattcatg gtcactcaac gtcgcaatat
      181 cgccttggag aattttatct tcatggtagc gacggtaaac cactggatta tacacaggcg
      241 agatactggt atgagcaatc agcggaacag gaaaatccac gcgcgcaaag taaactgggg
      301 tggatctacc tcaaaggtct gggggtcaaa cccgacaccc gtaaagcaat tctctggtat
      361 aaggaagcag ctgaacaagg gtatgctcat gctcaatata ctttaggttt gatctacaga
      421 aatggctcag gtattaatgt taaccattat gaatctcaaa aatggttaaa actggccgcc
      481 aaacaacatt acaaaaatgc ggaaagatta cttgccgggc ttcccgcaca ttaacgtcga
      541 ctgtcacccg aacagatgga gtattttccc tatcaaacca gcaaagataa aaatatagaa
      601 aataatttta atgatgccca gacagcctgg cccaccatcg tcaacgggca ttggctgcgg
      661 ttgcggctcc ggttcaacag tttgcttctc ggtaaaattc gccgcctgaa ttaataatcg
      721 acgaataatt aatgcttcca gtggacaacg attttctgca tcaaggcggc tcacaatcgg
      781 cattaatgat tcttctgtag gttggcaggc ctgcactaat tgtttggcaa ctagatataa
      841 tggccataag gtatgttctg tatcacgcgt gagtgagatc cgcggcttac gtcctttgtg
      901 caaaaccatc tcgaccagtg aacgccccag cgcagagagt ttttcatcgc tgagtatttc
      961 gtataaatga aaacgcgtac gggcgctgtc gccggggaca taaagtagcg gttttccctg
     1021 atcgttaacc agatcacgcg cttcaatcat catcaccagt aatgggtaat aatcgacccg
     1081 atgctgacgg caccattgca acattaaagc atccgcctgg gtggagggat actcgcgcca
     1141 gtagtcacaa agttctgcca acaggctttc gccttctcca caatagacgc gttgcgcgta
     1201 ttcataataa ggcgcatctt cattatcagg ttcagtttcc cgccatgact gggcgtaatc
     1261 cagaagttcg gggatatcca ggcgacctgc gctataccag cggagtaaat ttctgtgcag
     1321 ttttgcatca tcggggataa tcactgcgcg atgttgcgct aaatacaatg tcagccattg
     1381 tggatgcgat gaccaaatcc gagcgaacat ttggtaaaaa tcgatggtgt cattttgcac
     1441 ggcaacgggc agatgcagaa tggtctggaa gttaaaaaca ttccccttcg caatggcata
     1501 taaaaaggat tccagttctt cttcgtctat ttccccggta ttttcctcct gtaaccaccg
     1561 caatctttct gctaataaca ccacgcactc gaaggataaa tgggcagtgt tcatggcgat
     1621 tgtgcacagc gaccagcgta attcatcaat ctcctccatc gagcaataat ttaattgctg
     1681 aatgaatcgc tgccaggcgg agggcagaaa acgttcacta tcagaggcaa gtaacgcacg
     1741 aaaggcgagc agaatttcat gttctgctac ctcatattct tctggttgcc aaacagattt
     1801 agcaggcgac tgcgcaatcc gtagcgcctc ctcatacgcc tgacgaagtt gtttaaaacc
     1861 ctgcggatcg gtttctggat gaaaggacgg taacagcgcc agataagcgc ggcggataat
     1921 atcgacgtca gtcgtttcct ctatatcgag gatcttccag caatttttca taggtcgctc
     1981 atatccttaa gcgtttccgg gcatgcagaa tagtaagcca atggttgcca ggacaaggta
     2041 gggtaatacg catcatcact ggcaaataat tgataaaaca tatcattgcc ggaatcgtcg
     2101 tattctttac gcgctaagaa ttcgcgtaat aaaggcagat gatcatcttc gggagactgc
     2161 caatattgcc gaccaaaggt ataaccggca aagtattgcc gccagttact ataataacgt
     2221 agagcccgta gatgaatgcg cgactggatc catagacttt cttcttcgct caaccagtta
     2281 ttaagtacgc ccattcggct taaaaaaccc atccggacat aatcccaggc tttgattccc
     2341 ccttcgccac agcattcggc ggtgctggcg acaaattgcg cataagcctg accttgctca
     2401 tttagttcag caagatagtc acgccattca catggcgaat aacgaaacca gcggtgataa
     2461 aaccctgcca accgagcggc atgaccgtta tcgatcattc ggtgaattgt gcgcagcagg
     2521 tcatcacggt catcaattcc ccatgaggaa gaaaggtcaa aaaagcatgt acctaaatac
     2581 attttgggtg atgaatgcga aggtaaacag cattcattgc gtatttccat cggagtggaa
     2641 agtgcaaaca atattttttg cgactccatg tccatataat ttatccttaa atattcatta
     2701 aatgaatatt agccgcattg cgaggctcgt ttatttatac ttttctgacg cgacataata
     2761 cgcataaaat aaggcttacg caaaaatgga acacataaaa atataatatg ttttatctgc
     2821 aaccataagg aaatgataat gattttcacg tcaagttgct gcgataattt atcaatagat
     2881 gagattatcg aacgtgctga aaaaggcgat tgcgaggctc aatatattgt tgggttttat
     2941 tataatcgcg atagcgcaat tgattctccg gacgacgaaa aagcctttta ctggctgaag
     3001 ctggccgctg agcaaggtca ttgtgaagca cagtattcct tagggcaaaa gtataccgag
     3061 gataaaagcc gtcataaaga taatgagcaa gccatcttct ggctgaaaaa agctgcccta
     3121 caaggccata ctttcgcttc caacgccctt ggctggacac tggatcgtgg agaagccccc
     3181 aattataaag aagcggttgt ctggtatcag atagccgcgg agagcggaat gtcttatgcg
     3241 caaaataatc ttgggtggat gtacagaaat ggcaacggag tcgcaaaaga ctatgcgctg
     3301 gcatttttct ggtacaaaca agctgcatta caaggccata gtgacgcgca aaacaatctg
     3361 gccgatcttt atgaagacgg aaaaggcgtt gctcaaaaca agacactcgc cgcattctgg
     3421 tatttgaaaa gcgcacagca gggtaatcgg cacgcccagt ttcaaattgc atgggattat
     3481 aacgctggcg aaggggtgga ccaggactat aagcaagcga tgtactggta tctgaaggct
     3541 gccgctcagg ggagcgtcgg cgcttacgtc aacatcggtt atatgtataa acacggacaa
     3601 ggcgttgaga aagattatca ggctgccttt gaatggttta cgaaagccgc tgaatgcaat
     3661 gacgccactg cctggtataa cctggccatt atgtatcact acggagaagg aagacctgtc
     3721 gatctccgac aggctctcga cctgtatcgt aaagttcagt catccggaac cagagatgtc
     3781 agtcaggaaa ttcgtgagac tgaagattta ctgtagagat aaaaacaagg gccggggaat
     3841 ttcattcggc ccatattctc tttattgctg tgcgaaatca gactattacg gctcaaacgg
     3901 gcgtctctgg aactggtcat gaccacattt cgggcatagc gtcagcactt ccggtgtgta
     3961 gatcgggaga tggaagtgac atttctcgca gaccagattt cccagcccga ccacttctcc
     4021 gctgtgataa accccatgat gattgaggtc ctggaaaact tcgcgccatt caagctgcgt
     4081 tttatcggtg atgtctgcca gctcctgcca caagctttct ttaatcaccc gcataaagac
     4141 gctgtcagat tcttctttca ggctctcttc atagctcatg gcgaactctt ccaggtcacg
     4201 tctgacagct cgcgtcagct catcgacctc ggttcgcgtt aactcccctg tttttattac
     4261 gcgctcgcgc gcctgttcca ccagtgcgtc gatatcacgt tcgccattgc gcaggcgttc
     4321 gctcagtgac gcaaccagtt cacggtaata ttgagcaacc ttgttcatcg tttcatctcc
     4381 cgggtcgtta actgactata ataatagacg ttctttgttc cttgctttgc taatacgccc
     4441 acaaactctg taaattaatg tatgaataat ccgggcatca tttcaacgtc gagtgcgcga
     4501 aaggctgttt tgacgcggac gtttgggcta tgctatgcgg atctgaaaaa ccacctcaac
     4561 gctacatttg tagccgtatt gaaaacagga ccactggctg ccatgcaaga gcaataccgc
     4621 ccggaagaga tagaatccaa agtacagctt cattgggatg agaagcgcac atttgaagta
     4681 accgaagacg agagcaaaga gaagtattac tgcctgtcta tgcttcccta tccttctggt
     4741 cgactacaca tgggccacgt acgtaactac accatcggtg acgtgatcgc ccgctaccag
     4801 cgtatgctgg gcaaaaacgt cctgcagccg atcggctggg acgcgtttgg tctgcctgcg
     4861 gaaggcgcgg cggtgaaaaa caacaccgct ccggcaccgt ggacgtacga caacatcgcg
     4921 tatatgaaaa accagctcaa aatgctgggc tttggttatg actggagccg cgagctggca
     4981 acctgtacgc cggaatacta ccgttgggaa cagaaattct tcaccgagct gtataaaaaa
     5041 ggcctggtat ataagaagac ttctgcggtc aactggtgcc cgaacgacca gaccgtactg
     5101 gcgaacgaac aagttatcga cggctgctgc tggcgctgcg ataccaaagt tgaacgtaaa
     5161 gagatcccgc agtggtttat caaaatcact gcttacgctg acgagctgct caacgatctg
     5221 gataaactgg atcactggcc agacaccgtt aaaaccatgc agcgtaactg gatcggtcgt
     5281 tccgaaggcg tggagatcac cttcaacgtt aacgactatg acaacacgct gaccgtttac
     5341 actacccgcc cggacacctt tatgggttgt acctacctgg cggtagctgc gggtcatccg
     5401 ctggcgcaga aagcggcgga aaataatcct gaactggcgg cctttattga cgaatgccgt
     5461 aacaccaaag ttgccgaagc tgaaatggcg acgatggaga aaaaaggcgt cgatactggc
     5521 tttaaagcgg ttcacccatt aacgggcgaa gaaattcccg tttgggcagc aaacttcgta
     5581 ttgatggagt acggcacggg cgcagttatg gcggtaccgg ggcacgacca gcgcgactac
     5641 gagtttgcct ctaaatacgg cctgaacatc aaaccggtta tcctggcagc tgacggctct
     5701 gagccagatc tttctcagca agccctgact gaaaaaggcg tgctgttcaa ctctggcgag
     5761 ttcaacggtc ttgaccatga agcggccttc aacgccatcg ccgataaact gactgcgatg
     5821 ggcgttggcg agcgtaaagt gaactaccgc ctgcgcgact ggggtgtttc ccgtcagcgt
     5881 tactggggcg cgccgattcc gatggtgacg ctggaagacg gtaccgtaat gccgaccccg
     5941 gacgaccagc tgccggtgat cctgccggaa gatgtggtaa tggacggcat taccagcccg
     6001 attaaagcag atccggagtg ggcgaaaact accgttaacg gtatgccagc actgcgtgaa
     6061 accgacactt tcgacacctt tatggagtcc tcctggtact atgcgcgcta cacttgcccg
     6121 cagtacaaag aaggtatgct ggattccgaa gcggctaact actggctgcc ggtggatatc
     6181 tacattggtg gtattgaaca cgccattatg cacctgctct acttccgctt cttccacaaa
     6241 ctgatgcgtg atgcaggcat ggtgaactct gacgaaccag cgaaacagtt gctgtgtcag
     6301 ggtatggtgc tggcagatgc cttctactat gttggcgaaa acggcgaacg taactgggtt
     6361 tccccggttg atgctatcgt tgaacgtgac gagaaaggcc gtatcgtgaa agcgaaagat
     6421 gcggcaggcc atgaactggt ttataccggc atgagcaaaa tgtccaagtc gaagaacaac
     6481 ggtatcgacc cgcaggtgat ggttgaacgt tacggcgcgg acaccgttcg tctgtttatg
     6541 atgtttgctt ctccggctga tatgactctc gaatggcagg aatccggtgt ggaaggggct
     6601 aaccgcttcc tgaaacgtgt ctggaaactg gtttacgagc acacagcaaa aggtgatgtt
     6661 gcggcactga acgttgatgc gctgactgaa aatcagaaag cgctgcgtcg cgatgtgcat
     6721 aaaacgatcg ctaaagtgac cgatgatatc ggccgtcgtc agaccttcaa caccgcaatt
     6781 gcggcgatta tggagctgat gaacaaactg gcgaaagcac caaccgatgg cgagcaggat
     6841 cgcgctctga tgcaggaagc actgctggcc gttgtccgta tgcttaaccc gttcaccccg
     6901 cacatctgct tcacgctgtg gcaggaactg aaaggcgaag gcgatatcga caacgcgccg
     6961 tggccggttg ctgacgaaaa agcgatggtg gaagactcca cgctggtcgt ggtgcaggtt
     7021 aacggtaaag tccgtgccaa aatcaccgtt ccggtggacg caacggaaga acaggttcgc
     7081 gaacgtgctg gccaggaaca tctggtagca aaatatcttg atggcgttac tgtacgtaaa
     7141 gtgatttacg taccaggtaa actcctcaat ctggtcgttg gctaagcgcg ggaggaagcg
     7201 tgcgatatct ggcaacattg ttgttatctc tggcggtgtt aatcaccgcc gggtgtggct
     7261 ggcatctgcg tgataccacg caggttcctt ccactatgaa ggtcatgatc ctggactcag
     7321 gcgatccgaa cgggccatta agccgtgcgg tgcgtaacca gttacgtctg aatggtgtcg
     7381 agttgcttga taaagaaacc acgcgtaagg acgttccatc cttgcgtttg ggtaaagtga
     7441 gcatcgcgaa agataccgca tcggtattcc gtaacggtca aacagcagag tatcagatga
     7501 tcatgacggt taatgcgacc gtgttgatcc ccggccgtga tatctacccg attagcgcca
     7561 aagtcttccg ttcgttcttc gataacccgc aaatggcgtt agcgaaagat aacgaacaag
     7621 acatgatcgt aaaagagatg tacgaccgtg ctgccgaaca gctgattcgt aagctgccaa
     7681 gcatccgtgc tgcggatatt cgttccgacg aagaacagac gtcgaccaca acggatactc
     7741 cggcaacgcc tgcacgcgtc tccaccacgc tgggtaactg atgattcggt tgtacccgga
     7801 acaactccgc gcgcagctca atgaagggct gcgcgcggcg tatcttttac ttggtaacga
     7861 tcctctgtta ttgcaggaaa gccaggacgc tgttcgtcag gtagctgcgg cacaaggatt
     7921 cgaagaacac cacacttttt ccattgatcc caacactgac tggaatgcga tcttttcgtt
     7981 atgccaggct atgagtctgt ttgccagtcg acaaacgcta ttgctgttgt taccagaaaa
     8041 cggaccgaat gcggcgatca atgagcaact tctcacactc accggacttc tgcatgacga
     8101 cctgctgttg atcgtccgcg gtaataaatt aagcaaagcg caagaaaatg ccgcctggtt
     8161 tactgcgctt gcgaatcgca gcgtgcaggt gacctgtcag acaccggagc aggctcagct
     8221 tccccgctgg gttgctgcgc gcgcaaaaca gctcaactta gaactggatg acgcggcaaa
     8281 tcaggtgctc tgctactgtt atgaaggtaa cctgctggcg ctggctcagg cactggagcg
     8341 tttatcgctg ctctggccag acggcaaatt gacattaccg cgcgttgaac aggcggtgaa
     8401 tgatgccgcg catttcaccc cttttcattg ggttgatgct ttgttgatgg gaaaaagtaa
     8461 gcgcgcattg catattcttc agcaactgcg tctggaaggc agcgaaccgg ttattttgtt
     8521 gcgcacatta caacgtgaac tgttgttact ggttaacctg aaacgccagt ctgcccatac
     8581 gccactgcgt gcgttgtttg ataagcatcg ggtatggcag aaccgccggg gcatgatggg
     8641 cgaggcgtta aatcgcttaa gtcagacgca gttacgtcag gccgtgcaac tcctgacacg
     8701 aacggaactc accctcaaac aagattacgg tcagtcagtg tgggcagagc tggaagggtt
     8761 atctcttctg ttgtgccata aacccctggc ggacgtattt atcgacggtt gatatgaaat
     8821 ctttacaggc tctgtttggc ggcacctttg atccggtgca ctatggtcat ctaaaacccg
     8881 tggaaacgct ggcgaatttg attggtctga cgcgggtcac aatcatccct aataatgttc
     8941 ctccgcatcg tccccagccg gaagcgaaca gcgtgcagcg taaacacatg cttgaactgg
     9001 cgattgccga caagccatta tttactcttg atgaacgcga gctaaagcgc aatgccccct
     9061 cttacactgc gcaaacactg aaagagtggc ggcaggaaca aggaccggac gtgccgctgg
     9121 cgtttattat tggtcaggat tcactgctga cctttccgac ctggtacgaa tacgaaacga
     9181 tactcgacaa tgcacatttg atcgtctgtc ggcgtccagg ttacccactt gaaatggcgc
     9241 aaccgcaata ccagcaatgg ctggaagatc atttgacaca taacccggaa gatcttcacc
     9301 ttcagcctgc cggtaaaatt tatctggctg aaacgccgtg gtttaacatc tcggcgacca
     9361 tcatccgcga acgtttgcaa aacggtgaat catgtgagga tttattgccg gaaccggtac
     9421 tgacttacat taaccaacaa ggcttgtatc gctgatacct gtcgttacgg agggcatgat
     9481 gcgactgtgg ttaattcgtc atggtgaaac gcaagcgaat atcgatggtc tttacagcgg
     9541 tcatgcgccc acccccctga ccgcgcgcgg tattgagcaa gcgcaaaatc tgcatacgct
     9601 gctacatggt gtttcctttg atctggtttt atgcagtgaa ctggaacggg cacagcatac
     9661 cgcgcgactg gttctcagtg accgccagct ccccgtgcaa atcatacctg aactcaacga
     9721 aatgtttttt ggcgactggg agatgcgaca tcatcgcgac ctcatgcaag aagatgccga
     9781 aaactatagc gcgtggtgca atgactggca gcatgcaatc cccacgaacg gtgaaggatt
     9841 tcaggcattt tcgcaacgtg tggaacgctt tatcgcaagg cttagtgaat ttcagcacta
     9901 tcagaatatt ttagtcgtca gccatcaggg tgtactgagt ctgttaatcg cccgtttaat
     9961 tggcatgcct gccgaggcta tgtggcattt tcgcgttgac caggggtgtt ggagcgccat
    10021 tgatatcaac caaaaattcg cgacgctacg cgtcctcaat agccgtgcca tcggggtcga
    10081 gaatgcatga cttttctgtt tttttacggg taagccgcaa cgaccattga cagacccggg
    10141 caggctgata ttctccgcag ccagactttt tccgccagac acgactttgt agaaattgtt
    10201 ttacaaaaat ggcgatgcaa tctgcggcgc ggggtgggat gatagcccac tttcgaaagc
    10261 cgattcggcg acaattgtcc cgaaatcgcc tctggttcag gtatactgac agaccatttt
    10321 tatctatttg attcacccag ggggaaaact tgcagggtaa agcactccag gattttgtta
    10381 tcgacaaaat tgatgacctc aaaggtcagg acatcatcgc cttagacgtt cagggcaaat
    10441 ccagcatcac cgactgcatg atcatctgta cgggtacgtc cagccgtcat gttatgtcca
    10501 ttgctgacca cgttgtgcag gagtctcgcg cagcgggcct gttaccgctc ggcgtagaag
    10561 gtgaaaacag cgccgactgg attgtcgtgg atttgggcga tgtgattgtc catgtcatgc
    10621 aggaagagag ccgtcgcctg tatgaactgg aaaaactctg gagttaatgc gtgaagctgc
    10681 aacttgtcgc cgtgggaacg aaaatgccgg actgggtaca aaccggtttt accgagtacc
    10741 tgcgtcgttt tccgaaagat atgcccttcg agctgattga aattccggcc ggaaaacgcg
    10801 gcaagaatgc ggacatcaag cgcatactcg acaaagaggg tgagcagatg ttggcggccg
    10861 caggcaaaaa ccgcattgtc accctcgata ttccaggcaa gccctgggat acgccgcagt
    10921 tagccgctga gctggaacgc tggaagctgg atggtcgcga cgtcagtcta ctgattggcg
    10981 ggcctgaagg gttgtcgcct gcctgtaaag cggcggctga gcagagctgg tcgctgtcgg
    11041 cgcttaccct cccccatccg ctggttcgcg tgctggtcgc agagagtctg taccgggcgt
    11101 ggagcatcac caccaaccat ccttatcacc gtgagtgata agggagcttt gagtagaaaa
    11161 cgcagcggat gaaactacag aactcttttc gcgactatac ggcagagtcc gcgctgtttg
    11221 tgcgccgggc gctggtcgcc tttttgggga ttttgctgct gaccggcgtg cttatcgcca
    11281 acctgtataa tctgcaaatt gttcgcttta ccgactacca gacccgctct aatgaaaacc
    11341 gcattaagct ggtgcctatc gcgcccagcc gcggcattat ctacgatcgt aacggtatcc
    11401 ctctggccct caaccgcact atctaccaga tagaaatgat gccggagaaa gtcgataacg
    11461 tgcagcaaac gctggacgct ttgcgcagcg tggtagatct gaccgatgac gatattgctg
    11521 cattccgaaa agagcgcgca cgttcacacc gtttcacctc tattccggtg aaaactaacc
    11581 tgaccgaagt acaagtagct cgctttgccg tcaatcagta ccgttttccg ggtgtcgaag
    11641 ttaaaggcta taaacgtcgt tactatcctt acggttcggc gttgacccac gtcatcggct
    11701 atgtgtcgaa aatcaacgat aaagacgtcg aacgcctgaa taatgacggc aaactggcca
    11761 actatgcggc aacgcatgat atcggtaagc tgggcattga gcgttactat gaagatgtgc
    11821 tgcacggtca gaccggttat gaagaggttg aagttaacaa ccgtgggcgt gttattcgcc
    11881 agttaaaaga agtaccaccg caagccggac acgatattta cctgacgctg gatctcaaac
    11941 tccagcaata tattgaaacg ctgctggcgg gtagccgcgc agctgtggta gtcaccgatc
    12001 cgcgtacagg tggggtgctg gcgctggttt ccacgcctag ttatgaccca aacttgtttg
    12061 ttgacggtat ctccagcaaa gattattccg ccttgttgaa cgatccgaat acaccgctgg
    12121 tgaaccgcgc cacacagggg gtttatcctc ctgcgtctac agttaaaccc tatgtggcgg
    12181 tttcggcatt gagcgccggg gtgatcacgc gcaatacgac gctgtttgac ccaggctggt
    12241 ggcaactgcc aggttcggaa aaacgttatc gtgactggaa aaaatggggc cacgggcgtc
    12301 tgaatgtcac aagatcgctg gaagaatctg cggatacctt cttctatcag gtggcctacg
    12361 atatggggat cgatcgcctc tccgaatgga tgggtaaatt cggttatggt cattacaccg
    12421 gtatcgacct ggcggaagaa cgttccggca acatgcctac ccgcgaatgg aaacagaaac
    12481 gctttaaaaa accgtggtat cagggtgaca ccattccggt tggtatcggt cagggttact
    12541 ggacagcgac cccaatccag atgagtaagg cactgatgat cctgattaat gacggtatcg
    12601 tgaaggttcc tcatttgctg atgagcaccg ccgaagacgg caaacaggtg ccatgggtac
    12661 agccgcatga accgcccgtc ggcgatattc attccggtta ctgggagctg gcgaaagacg
    12721 gtatgtacgg tgttgctaac cgccctaacg gtacggcgca taaatacttt gctagcgcac
    12781 cgtacaaaat tgcggcgaaa tccggtaccg ctcaggtctt cggtctgaaa gcgaacgaaa
    12841 cctataatgc gcacaaaatt gccgagcgtt tacgtgacca caaactgatg accgcctttg
    12901 cgccatacaa caatccgcaa gtggctgtcg ccatgattct ggagaacggt ggtgcgggtc
    12961 cggcggttgg tacactgatg cgccagatcc tcgaccacat tatgctgggt gataacaaca
    13021 ccgatctgcc tgcggaaaat ccagcggttg ccgcagcgga ggaccattaa tcatgacgga
    13081 taatccgaat aaaaaaacat tctgggataa agtccatctc gatcccacaa tgctgctgat
    13141 cttactggca ttgctggttt acagcgccct ggttatctgg agcgccagcg gtcaggatat
    13201 tggcatgatg gagcgtaaaa tcggccaaat cgcgatgggt ctggtcatca tggtggtgat
    13261 ggcgcaaatt cctccacgcg tttatgaagg ctgggccccc tatctctata tcatctgtat
    13321 tattttgctg gtggcggtag atgctttcgg tgccatctct aaaggtgctc aacgctggct
    13381 ggacctcggt attgttcgtt ttcagccgtc ggaaattgcc aaaatagccg taccactgat
    13441 ggttgcgcgc tttatcaacc gcgacgtttg cccgccatcg ttgaagaaca ctggcatcgc
    13501 gctggtgctg atatttatgc ccacgctgct ggtggctgca cagcctgacc tgggaacatc
    13561 aatcctcgtt gcgctttccg gtctgtttgt actgttcctc tctggcctta gctggcgtct
    13621 gattggcgtc gcagtagtgc tggtagcggc gttcattccg attctgtggt tcttcctgat
    13681 gcatgattac cagcgccagc gcgtaatgat gctcctggac ccggaatcag acccactcgg
    13741 cgcgggctat cacattattc agtctaaaat tgctattggc tccggcggat tacgcggcaa
    13801 aggctggctg cacggcactc agtcacagct tgaatttctc cccgaacgcc atactgactt
    13861 tatcttcgcg gtactggcgg aagagctggg attagtgggc attctgattc tgctcgctct
    13921 ctacattctg ctgatcatgc gcgggctgtg gatagccgcc agagcgcaaa ccacctttgg
    13981 tcgcgtcatg gctggcggct taatgctgat attattcgtt tatgtcttcg taaatattgg
    14041 tatggtaagc ggtattctgc cggttgtagg ggttccgctc ccactggtca gttatggagg
    14101 atcggcgcta attgtgctga tggctgggtt cgggattgta atgtcaatcc acacccacag
    14161 gaaaatgttg tcgaaaagcg tgtaagaggt gcgcaatgcg taagcagtgg ctcgggatct
    14221 gcatcgcggc aggaatgctc gcggcatgta caagcgatga tggtcagcaa cagacggtaa
    14281 gtgtaccgca gcctgcggta tgtaacggcc ctatagttga aattagcggg gcggacccgc
    14341 gtttcgaacc actgaacgcg acggcaaatc aggattacca gcgcgacggt aaaagctaca
    14401 aaatcgtgca ggatccgtct cgatttagcc aggcgggact ggcggcaatc tatgatgccg
    14461 aacccggcag taacctgacg gcctctggcg aagcattcga tccgacacag ctgacggcag
    14521 cccatccaac gcttccgatc cccagctacg ccagaatcac taacctggct aacgggcgaa
    14581 tgatcgtggt gcgcattaat gatcgcggcc cttacggcaa cgaccgcgtt atttcacttt
    14641 ctcgcgcggc agctgaccgt cttaacacgt caaacaacac caaagttcgt atcgatccga
    14701 ttattgttgc ccaggatggt tcgctttctg gtcctggtat ggcttgtacc acagtcgcca
    14761 aacagactta cgccctgcct gcacctcccg atttaagcgg tggcgcggga acaagttcag
    14821 tgtctggccc gcagggtgac attcttccgg tcagtaattc gacgctaaaa agcgaagatc
    14881 cgaccggcgc gccggtaacc agtagcggtt tcctcggcgc accaacgacc ttagcgcctg
    14941 gtgtactgga aggcagcgaa ccgacgcctg cgccacagcc cgttgttaca gctccgtcga
    15001 caacgcctgc aacctcgcct gcaatggtga caccgcaagc cgtctcgcaa agcgccagcg
    15061 gcaactttat ggtgcaagtc ggggccgtaa gcgatcaggc tcgtgcgcaa cagtaccaac
    15121 agcaactggg acagaagttc ggcgtccccg gtcgcgtaac tcaaaatggc gcggtctggc
    15181 ggatccagct tggcccattc gccagcaaag ccgaagccag taccttgcag caacgtttgc
    15241 aaaccgaagc ccaattacag tcatttatta ctaccgcgca gtagcgtaaa gcaggcatct
    15301 gatgtgtcaa tttctgtaaa tgacgttaac aaagtcacgc ggaaagtcag atgcctgccg
    15361 gtagtgcatt tgctatagta gggcactttt ttaattccat cacggatgtc gtagttcaga
    15421 ccatgaatac cattttttcc gctcgtatca tgaagcgcct ggcgctcacc acggctcttt
    15481 gcacagcctt tatctctgct gcacatgccg atgacctgaa tatcaaaact atgatcccgg
    15541 gtgtaccgca gatcgatgcg gagtcctaca tcctgattga ctataactcc ggcaaagtgc
    15601 tcgccgaaca gaacgcagat gtccgccgcg atcctgccag cctgaccaaa atgatgacca
    15661 gttacgttat cggccaggca atgaaagccg gtaaatttaa agaaactgat ttagtcacta
    15721 tcggcaacga cgcatgggcc accggtaacc cggtgtttaa aggttcttcg ctgatgttcc
    15781 tcaaaccggg catgcaggtt ccggtttctc agctgatccg cggtattaac ctgcaatcgg
    15841 gtaacgatgc ttgtgtcgcc atggccgatt ttgccgctgg tagccaggac gcttttgttg
    15901 gcttgatgaa cagctacgtt aacgcactgg gcctgaaaaa tacccacttc cagacggtac
    15961 atggtctgga tgctgatggt cagtacagct ccgcgcgaga tatggcgctg atcggccagg
    16021 cattgatccg tgacgtaccg aatgaatact cgatctataa agaaaaagaa tttacgttta
    16081 acggtattcg ccagctgaac cgtaacggcc tgttatggga taacagcctg aatgtcgacg
    16141 gcatcaaaac cggacacact gacaaagcag gttacaacct tgttgcttct gcgactgaag
    16201 gccagatgcg cttgatttct gcggtaatgg gcggacgtac ttttaaaggc cgtgaagccg
    16261 aaagtaaaaa actgctaacc tggggcttcc gtttctttga aaccgttaac ccactgaaag
    16321 taggtaaaga gttcgcctct gaaccggttt ggtttggtga ttctgatcgc gcttcgttag
    16381 gggttgataa agacgtgtac ctgaccattc cgcgtggtcg catgaaagat ctgaaagcca
    16441 gctatgtgct gaacagcagt gaattgcatg cgccgctgca aaagaatcag gtcgtcggaa
    16501 ctatcaactt ccagcttgat ggcaaaacga tcgagcaacg cccgctggtt gtgttgcaag
    16561 aaatcccgga aggtaacttc ttcggcaaaa tcattgatta cattaaatta atgttccatc
    16621 actggtttgg ttaaaaatta aacacttgaa agtgtaattt ccgtccccat atactaagca
    16681 tcagtaaaaa actcccgcct tctggcggga gttgctattt aattacgtta cgccggagct
    16741 gacatgaaaa ccaaacttaa cgaactgctt gaattcccta ctccttttac ttacaaagtt
    16801 atggggcagg cgttacctga gctggttgat caggtggttg aagtggtaca gcgccatgcg
    16861 ccaggtgact acaccccaac ggtaaaacca agcagcaaag gcaactacca ctcggtatct
    16921 atcactatca acgccactca tatcgagcag gttgaaacac tgtatgaaga actgggcaaa
    16981 atcgatattg tccgcatggt tctgtaactc gcttctccgt tacccggctc ctggtcgggt
    17041 aactcccctc tcctcgctgt gatatacttt tcccccactt ttactcattc tccacggaga
    17101 tgccgttttg tatcaggata aaattcttgt ccgccagctc ggtcttcagc cttacgagcc
    17161 aatctcccag gctatgcatg aattcaccga tacccgcgat gatagtaccc ttgatgaaat
    17221 ctggctggtc gagcactatc cggtattcac ccaaggtcag gcaggaaaag cggagcacat
    17281 tttaatgccg ggtgatattc cggtgatcca gagcgatcgc ggtgggcagg tgacttatca
    17341 cgggccgggg caacaggtga tgtatgtgtt gcttaacctg aaacgccgta aactcggtgt
    17401 gcgtgaactg gtgaccttgc ttgagcaaac agtggtgaat accctggctg aactgggtat
    17461 agaagcgcat cctcgggctg acgcgccagg tgtctatgtt ggggaaaaga aaatttgctc
    17521 actgggttta cgtattcgac gcggttgttc attccacggt ctggcattaa acgtcaatat
    17581 ggatctttca ccatttttac gtattaatcc ttgtgggtat gccggaatgg aaatggctaa
    17641 aatatcacaa tggaaacccg aagcgacgac taataatatt gctccacgtt tactggaaaa
    17701 tattttagcg ctactaaaca atccggactt cgaatatatt accgcttaat tccatacatc
    17761 aatggcccaa tttacactgg gtcattactc ataatatctg ctaatgcttt acatctcctt
    17821 cgcgtttgta tattttcttt atcacttgca gaaatgcggt gccacgcctt gctccgtaac
    17881 tcaccccatt gattaaccta ttgaaatagt tgattatgg
//
LOCUS       DAPHKZ010000093        17562 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.093, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000093 DAPHKZ010000000
VERSION     DAPHKZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17562
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.093"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            84..1223
                     /gene="arnB"
                     /locus_tag="RH288_003252"
     CDS             84..1223
                     /gene="arnB"
                     /locus_tag="RH288_003252"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HDV4032283.1"
                     /translation="MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQ
                     LTGNQHAIAVSSATAGMHITLMALKIGKGDEVITPSLTWVSTLNMISLLGATPVMVDV
                     DRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
                     TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDR
                     QTWGRAPQAEVLTPGYKYNLTDINAAIALTQLVKLEHLNTRRREIAQQYQQALAALPF
                     QPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYR
                     ERFPTLSLPNTEWNSERICSLPLFPDMTTADADHVITALQQLAGQ"
     gene            1227..2195
                     /gene="arnC"
                     /locus_tag="RH288_003253"
     CDS             1227..2195
                     /gene="arnC"
                     /locus_tag="RH288_003253"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HDV4032284.1"
                     /translation="MFEIHPVKKVSVVIPVYNEQESLPELIRRTTTACESLGKEYEIL
                     LIDDGSSDNSAHMLVEASQAENSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDAD
                     LQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
                     CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREFGESKYSFMRLI
                     NLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE"
     gene            2195..4177
                     /gene="arnA"
                     /locus_tag="RH288_003254"
     CDS             2195..4177
                     /gene="arnA"
                     /locus_tag="RH288_003254"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HDV4032285.1"
                     /translation="MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGS
                     VARLAAERGIPVYAPDNVNHPLWVERIAQLSPDVIFSFYYRHLIYDEILQLAPAGAFN
                     LHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAIT
                     LHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLH
                     NMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEI
                     VTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTER
                     LLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGS
                     SRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIG
                     NPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIR
                     NAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS"
     gene            4174..5064
                     /locus_tag="RH288_003255"
     CDS             4174..5064
                     /locus_tag="RH288_003255"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HDV4032286.1"
                     /translation="MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDN
                     MGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHE
                     VGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIE
                     AKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLL
                     NRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVV
                     RGNIAGREGWLGCQQIAGSR"
     gene            5064..6716
                     /gene="arnT"
                     /locus_tag="RH288_003256"
     CDS             5064..6716
                     /gene="arnT"
                     /locus_tag="RH288_003256"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HDV4032287.1"
                     /translation="MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLA
                     SGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFT
                     LRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
                     KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLT
                     VLPWGLAIAQREPNFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLP
                     GALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLA
                     AKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLW
                     AFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSR
                     YILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHR
                     QEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK"
     gene            6713..7048
                     /gene="arnE"
                     /locus_tag="RH288_003257"
     CDS             6713..7048
                     /gene="arnE"
                     /locus_tag="RH288_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HDV4032288.1"
                     /translation="MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLAL
                     ACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIG
                     GIVILGSTV"
     gene            7048..7434
                     /gene="arnF"
                     /locus_tag="RH288_003258"
     CDS             7048..7434
                     /gene="arnF"
                     /locus_tag="RH288_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416761.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HDV4032289.1"
                     /translation="MGLMWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFG
                     LDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFS
                     LKALLGVACIMSGLMLIFLPTTKQRY"
     gene            complement(7428..7694)
                     /gene="pmrD"
                     /locus_tag="RH288_003259"
     CDS             complement(7428..7694)
                     /gene="pmrD"
                     /locus_tag="RH288_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416762.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HDV4032290.1"
                     /translation="MEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGD
                     LLSPLQNALYCINREKLHTVKVLSASSYSPDEWERQCKVAGKTQ"
     gene            complement(7804..9159)
                     /gene="menE"
                     /locus_tag="RH288_003260"
     CDS             complement(7804..9159)
                     /gene="menE"
                     /locus_tag="RH288_003260"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HDV4032291.1"
                     /translation="MIFSDWPWRHWRQVRGETIALRLNDEQLNWRELCARVDELASGF
                     AVQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF
                     ALVPDGENTFPALTSLHIQLVEGAHAATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
                     ASAQGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFAS
                     TVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYAT
                     RDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGH
                     RPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQ
                     Q"
     gene            complement(9156..10118)
                     /gene="menC"
                     /locus_tag="RH288_003261"
     CDS             complement(9156..10118)
                     /gene="menC"
                     /locus_tag="RH288_003261"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HDV4032292.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGE
                     ISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDTLPQAA
                     NYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTPLKGQQFAKYVNPDYRDRIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     PDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLAR
                     IAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL"
     gene            complement(10118..10975)
                     /gene="menB"
                     /locus_tag="RH288_003262"
     CDS             complement(10118..10975)
                     /gene="menB"
                     /locus_tag="RH288_003262"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HDV4032293.1"
                     /translation="MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(10990..11748)
                     /gene="menH"
                     /locus_tag="RH288_003263"
     CDS             complement(10990..11748)
                     /gene="menH"
                     /locus_tag="RH288_003263"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HDV4032294.1"
                     /translation="MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLY
                     VDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAG
                     LCGVIVEGGHPGLQNAEQRAERQRSDRQWVQRFLTEPLTAVFADWYQQPVFASLNDDQ
                     RRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAA
                     ELAADCHVIPRAGHNAHRENPAGVIASLAQILRF"
     gene            complement(11745..13415)
                     /gene="menD"
                     /locus_tag="RH288_003264"
     CDS             complement(11745..13415)
                     /gene="menD"
                     /locus_tag="RH288_003264"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HDV4032295.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAEN
                     SAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLH
                     AGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSEL
                     QQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWL
                     ELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
                     ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKY
                     HRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(13504..14799)
                     /gene="menF"
                     /locus_tag="RH288_003265"
     CDS             complement(13504..14799)
                     /gene="menF"
                     /locus_tag="RH288_003265"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416768.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HDV4032296.1"
                     /translation="MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWL
                     ASQQTYPQFYWQQRNGDEEAVVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDP
                     SQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIQAKEFIATLVSIKPLPGLHLTT
                     TREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLN
                     LNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLM
                     ADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVI
                     CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKIS
                     GNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME"
     gene            complement(14878..15183)
                     /gene="elaB"
                     /locus_tag="RH288_003266"
     CDS             complement(14878..15183)
                     /gene="elaB"
                     /locus_tag="RH288_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HDV4032297.1"
                     /translation="MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAE
                     KALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(15238..15699)
                     /locus_tag="RH288_003267"
     CDS             complement(15238..15699)
                     /locus_tag="RH288_003267"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV4032298.1"
                     /translation="MIEWQDLHHSELSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDL
                     TGDNRHILGWKNDELVAYARILKSDDDLEPVVIGRVIVSEALRGEKVGQQLMSKTLET
                     CTHHWPDKPVYLGAQAHLQNFYQSFGFIPVTEVYEEDGIPHIGMAREVIQA"
     gene            15764..16681
                     /gene="rbn"
                     /locus_tag="RH288_003268"
     CDS             15764..16681
                     /gene="rbn"
                     /locus_tag="RH288_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416771.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HDV4032299.1"
                     /translation="MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQ
                     HQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVE
                     TALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPLEHPLECYGYRIEEHDKPGALN
                     AQALKAAGVPPGPLFQELKAGKTITLEDGRQINGADYLAAPVPGKALAIFGDTGPCDA
                     ALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYD
                     DKGCQHLLRECRSIFPATELANDFTVFNV"
     gene            16869..>17562
                     /locus_tag="RH288_003269"
     CDS             16869..>17562
                     /locus_tag="RH288_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416772.1"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deubiquitinase"
                     /protein_id="HDV4032300.1"
                     /translation="MMVTVVSNYCQLSQTQLSQTFAEKFTVTEELLQSLKKTALSGDE
                     ESIELLHNIALGYDKFGKEAEDILYHIVRTPTNETLSIIRLIKNACLKLYNLAHIAIN
                     SPLKSHDSDDLLFKKLFSPSKLMTIIGDEIPLISEKQSLSKVLLNDENNELSDGTNFW
                     DKNRQLTTDEIACYLQKIAANAKNTQVNYPTGLYVPYSTRTHLEDALNENIKSDPSWP
                     NEVQLFPINTGGH"
BASE COUNT         4132 a         4731 c         4418 g         4281 t
ORIGIN      
        1 tttcgctcca aatggcaaaa tatacacaac actctttata gcaaatataa gtggacaggt
       61 attcaatggc ggaaggaaaa gcaatgtcag aatttttgcc tttttcgcga ccagcaatgg
      121 gcgtggagga actcgctgca gttaaagagg ttctcgaatc cggttggatc acaaccggtc
      181 cgaagaatca ggcgcttgag caagcttttt gccagttgac gggaaatcag catgccatcg
      241 cggtcagttc agccaccgcc ggaatgcata tcacgctaat ggcgttgaaa attggcaagg
      301 gcgatgaagt gattacgcct tccctgacct gggtttcaac cctcaatatg atttccttgt
      361 tgggtgcaac gccggtaatg gtggatgtcg accgcgatac gctgatggtc acgcctgaag
      421 ctatcgagtc agccattacg ccacgcacta aagccatcat tccggtgcat tatgccggtg
      481 cgccagcaga tattgacgcc attcgcgcca ttggcgaacg ttacggcatc gcagttatcg
      541 aagatgctgc ccatgccgtc ggtacgtatt acaaagggcg acatattggc gcaaaaggta
      601 ccgctatttt ttcatttcat gccattaaaa atattacctg tgctgaaggt ggcctgattg
      661 taactgataa tgaaaacctt gcccgccagc tacggatgct gaaatttcac ggtctgggtg
      721 tcgatgccta tgacagacaa acctggggcc gtgcaccgca ggctgaagtc ttaacaccgg
      781 gctataagta caatctgacc gatattaacg ccgcgattgc cctgacacag ttagtcaaat
      841 tagagcacct caacacccgt cggcgcgaaa ttgcccagca atatcagcaa gcactggcag
      901 ctctcccctt tcagccatta agccttcccg cctggccgca cgttcacgcc tggcatctgt
      961 ttattattcg tgtcgatgaa caacgttgtg gtatcagtcg cgatgcgttg atggaagcgt
     1021 taaaagaaag aggcattggt accgggttac atttccgcgc cgctcacaca caaaaatatt
     1081 atcgcgagcg ttttcccacg ctgtcgttac cgaataccga atggaatagc gaacgcatct
     1141 gttctttgcc gctgttcccg gatatgacta ccgccgatgc cgaccatgtc atcacagccc
     1201 ttcagcaact cgcaggacaa taagccatgt ttgaaatcca ccctgttaag aaagtctcgg
     1261 tggttattcc cgtttataac gagcaggaaa gcttaccgga attaatcagg cgcaccacca
     1321 cagcctgtga atcgttgggg aaagagtatg agatcctgct gattgatgac ggcagtagcg
     1381 ataattccgc gcatatgctg gtcgaagcct cacaagcgga gaacagccat attgtgtcta
     1441 ttttgcttaa ccgcaattac gggcaacatt cagcgattat ggcgggattc agtcacgtta
     1501 ctggcgactt aattattacc cttgatgccg atctccagaa tccgccagaa gaaatccccc
     1561 gcctggtggc aaaagccgat gaaggttacg acgtggtagg gactgtacgc cagaaccgcc
     1621 aggacagctg gtttcgtaaa accgcttcga agatgattaa ccggcttatt cagcgcacca
     1681 ctggcaaagc gatgggtgat tacggttgta tgctgcgcgc ctatcgccgt catattgtcg
     1741 atgcgatgtt gcactgccat gaacgcagca cctttatccc gattctggcg aatatcttcg
     1801 cccgccgtgc cattgaaatt ccagtacatc atgccgagcg tgagtttggt gaatccaaat
     1861 acagttttat gcgcctgatt aatttgatgt acgacctggt gacctgcctt accacaacgc
     1921 cgctacgtat gctgagtctg ctcggcagca ttattgcgat tggaggtttt agcattgcgg
     1981 tgctgctggt gattttacgc ctgaccttcg gaccacaatg ggcggcagaa ggcgtcttta
     2041 tgctatttgc cgtgctgttt acttttattg gcgctcagtt tatcggcatg ggattactcg
     2101 gtgaatatat cggcaggatc tacaccgatg tccgcgcccg cccccgctat tttgttcagc
     2161 aagttatccg tccatccagc aaggaaaatg aataatgaaa accgtcgttt ttgcctacca
     2221 cgatatggga tgcctcggta ttgaagccct gctggctgcc ggttacgaaa ttagcgccat
     2281 ttttacccat actgataatc ccggtgaaaa agccttttat ggttcggtgg ctcgtctggc
     2341 ggcggaaaga ggcattccgg tttatgcgcc ggataacgtt aatcatccgc tgtgggtgga
     2401 acgcattgcc caactgtcgc cagatgtgat tttctctttt tattatcgcc atcttattta
     2461 cgacgaaatt ttgcagctcg ctcccgcagg tgcatttaat ctgcatggtt cgctgttacc
     2521 aaaatatcgt ggtcgcgcgc cgctgaactg ggtgctggtc aacggtgaaa cggaaactgg
     2581 cgttacattg caccgaatgg tgaaacgtgc cgatgccggg gccattgtgg cgcaactgcg
     2641 cattgccatt gcgccagacg atatcgctat tacgctgcat cataaattgt gccatgccgc
     2701 gcgccagcta ctggaacaga cattacccgc cattaaacac ggtaatattc tggaaatcgc
     2761 ccagcgcgaa aacgaagcca cctgttttgg tcgcagaacg ccggatgaca gtttccttga
     2821 atggcataaa ccggcatccg tactgcacaa catggtacgt gccgttgccg atccgtggcc
     2881 gggtgccttc agctatgttg gcaatcagaa attcaccgtc tggtcgtcgc gtgttcatcc
     2941 tcatgccagc aaagcacagc cggggagcgt gatttctgtt gcgccactgc tgattgcctg
     3001 tggcgatggc gcgctggaaa tcgtcaccgg acaggcgggc gacggcatta ctatgcaggg
     3061 ctcgcaatta gcgcagacgc tgggcctggt gcaaggttca cgcttgaata gccagcctgc
     3121 ctgcaccgcc cgacgccgta cccgggtact catcctcggg gtgaatggct ttattggcaa
     3181 ccatctgaca gaacgcctgc tgcgcgaaga tcattatgaa gtttacggtc tggatattgg
     3241 cagcgatgcg ataagccgtt ttctgaatca tccgcatttt cactttgttg aaggcgatat
     3301 cagtattcat tccgaatgga ttgagtatca tgtcaaaaaa tgtgatgtcg tcttgccgct
     3361 ggtggcgata gccacgccga ttgaatatac ccgcaacccg ctgcgcgtat ttgaactcga
     3421 ttttgaagag aatctgcgca ttatccgcta ctgcgtgaag taccgtaagc gaatcatctt
     3481 cccgtcaact tcagaagttt atgggatgtg tagcgataaa tacttcgatg aggaccattc
     3541 taatttaatc gtcggcccgg tgaataaacc acgctggatt tattcggtat caaaacaatt
     3601 acttgatcgg gtgatctggg cctatggcga aaaagagggt ttacagttca ccctcttccg
     3661 cccgtttaac tggatgggac cacgactgga taaccttaat gcagcgcgaa ttggcagctc
     3721 ccgcgctatt acgcaactca ttctcaatct ggtagaaggt tcaccgatta agctgattga
     3781 tggcggaaaa caaaaacgct gctttactga tattcgcgat ggtatcgagg cgttataccg
     3841 cattatcgaa aatgcgggaa atcgctgcga cggtgaaatt atcaacattg gcaatcctga
     3901 gaacgaagcg agcattgagg aactgggcga gatgctgctg gcgagcttcg aaaaacatcc
     3961 gctgcgccat catttcccac cgtttgcggg ctttcgcgtt gtcgaaagta gcagctacta
     4021 cggcaaagga tatcaggacg tagagcatcg taaaccgagc atccgcaatg cccaccgctg
     4081 cctggactgg gagccgaaaa ttgatatgca ggaaaccatc gacgaaacgc tggatttctt
     4141 cctgcgcacc gttgatctta cggataaacc atcatgacca aagtaggctt acgcattgat
     4201 gtcgatacct ttcgtggcac ccgtgaaggc gtgccgcgtc tgctggaaat cttgagtaag
     4261 cataatattc aggccagcat ttttttcagc gtcggcccgg acaatatggg ccgccatctc
     4321 tggcgactgg tgaagccaca gtttttgtgg aagatgctgc gctcaaacgc ggcatcgctt
     4381 tatggctggg atattttact ggcaggtacg gcctggccag gtaaagagat tggtcatgcc
     4441 aatgccgata tcattcgtga agcggctaaa catcacgaag tcggcctgca cgcctgggat
     4501 caccatgcct ggcaagcccg tagcggtaac tgggatcggc aaacaatgat cgacgatatt
     4561 gcacgcggtc ttcgcactct ggaagagatt atcggtcaac cggtaacctg ttctgccgct
     4621 gcgggctggc gtgccgacca gaaggtgatc gaagcaaaag aagcgttcca tttgcgctac
     4681 aacagcgatt gtcgtggggc catgccgttc cgtccattgc tcgaatcagg aaaccctggc
     4741 actgcgcaaa ttccggtgac cttacccacc tgggatgaag tgattggtcg ggatgtgaaa
     4801 gcagaagatt ttaacggttg gttactcaac cgcatcctgc gagataaagg cacgccggtt
     4861 tataccattc atgcagaagt tgaaggctgc gcttatcagc ataattttgt ggatctcctc
     4921 aaacgcgcag ctcaggaagg cgtgacattt tgccctttaa gcgaactgtt atcagagacg
     4981 ttgccgctcg gacaagttgt tcgcggaaat attgccggac gtgaaggctg gctgggttgc
     5041 caacaaattg cgggtagtcg ctgatgaaat cggtacgtta ccttatcggc ctcttcgcgt
     5101 ttattgcctg ctattacctg ttaccgatca gcacgcgtct gctctggcaa cccgatgaaa
     5161 cgcgttatgc ggaaatcagt cgagaaatgc tggcatccgg cgactggatt gtgccccatc
     5221 tgttagggct acgttatttc gaaaaaccca ttgccggata ctggattaac agcattgggc
     5281 aatggctatt tggcgcgaat aactttggtg tgcgggcagg cgttatcttt gcgaccctgt
     5341 taactgccgc gctggtgacc tggtttactc tgcgcttatg gcgcgataaa cgtctggctc
     5401 tactcgccac agtaatttat ctctcattgt ttattgtcta tgccatcggc acttatgccg
     5461 tgctcgatcc gtttattgca ttctggctgg tggcgggaat gtgcagcttc tggctggcaa
     5521 tgcaggcaca gacgtggaaa ggcaaaagcg caggattttt actgctggga atcacctgcg
     5581 gcatgggggt gatgaccaaa ggttttctcg cccttgccgt gccggtatta agcgtgctgc
     5641 catgggtagc gacgcaaaaa cgctggaaag atctctttat ttacggctgg ctggcggtta
     5701 tcagttgcgt actgacggtt ctcccttggg gactggcgat agcgcagcgg gagcctaact
     5761 tctggcacta ttttttctgg gttgagcata ttcaacgctt tgcactggat gatgcccaac
     5821 atagagctcc gttctggtac tacgtgccgg tcatcattgc cggtagcctg ccgtggctgg
     5881 gattactccc cggtgcactg tacacaggct ggaaaaaccg caagcattcc gcaaccgtct
     5941 atttgttgag ctggacgata atgccgctgc tgtttttctc cgtcgctaaa ggtaaattgc
     6001 ccacctatat tctttcctgc tttgcatctc tggcaatgct gatggcgcat tacgctttgc
     6061 tggcagcaaa aaataatcct ctggcgctgc ggattaatgg ctggattaac atcgcttttg
     6121 gcgtcactgg cattattgcc acatttgtgg tctccccgtg gggaccaatg aacacgccgg
     6181 tgtggcaaac cttcgagagc tataaagtct tttgtgcctg gtcgattttt tcgctatggg
     6241 catttttcgg ctggtacacc ttaacaaacg tcgaaaagac ctggcctttt gccgcgcttt
     6301 gcccgctggg gctggcgttg ctggtaggat tttcaattcc tgacagagtt atggaaggaa
     6361 aacatccgca attttttgtc gagatgacac aagaatcact tcagccaagc cgctatattc
     6421 ttactgatag cgtcggtgtt gccgcaggtc tggcatggag cctgcaacgc gatgacatca
     6481 tcatgtatcg ccagacaggt gagttgaaat acggccttaa ttatccggat gcgaaaggga
     6541 gatttgtcag cggtgatgag ttcgcaaact ggcttaatca acatcgtcag gaggggatta
     6601 ttactctcgt gctttcggtt gaccgcgatg aagatatcaa cagtctcgcc attccgcccg
     6661 cagatgccat cgatcgtcag gagcgtctgg tgctgattca gtatcgtccc aaatgatctg
     6721 gctaacatta gtctttgcca gcttgcttag cgttgccggg cagttgtgtc agaaacaggc
     6781 aacctgcttt gtggcgataa acaaacggcg caaacatatc gtgctgtggc tgggactggc
     6841 gctggcttgt cttggtcttg ccatggtgct ctggctgctg gtcttgcaga acgtaccggt
     6901 aggcattgct tacccgatgt taagtctgaa ttttgtctgg gtgacgctgg ctgcagtaaa
     6961 actgtggcac gaaccggtat cgccgcgtca ctggtgtggg gtggcgttca ttattggcgg
     7021 cattgtgatc ctcgggagta cggtgtaatg ggcctgatgt ggggattatt cagcgtcatt
     7081 attgcctcag ttgcgcaatt aagcctgggt tttgcggcga gtcatctgcc gccgatgacg
     7141 cacttatggg attttatcgc ggctctgtta gcttttggcc tggatgcccg gatactgtta
     7201 ctcgggctgc tgggttatct gctttccgtt ttttgttggt ataaaacgct tcataaactt
     7261 gcgctaagca aagcctatgc cttgctcagt atgagttatg tgctggtatg gattgcttca
     7321 atggtacttc ccggctggga agggactttt tcgctgaaag cactactggg agtagcctgt
     7381 attatgagcg ggttgatgct gattttcctg cccacgacaa aacaacgtta ctgagttttc
     7441 cctgccactt tacactgccg ttcccactca tcggggctat aactgcttgc cgagaggact
     7501 ttcaccgtat gcagcttttc acgattaata caataaagcg cattctgcaa aggcgagagt
     7561 aaatccccca ctttcacggc gaagtcactc ttcacttcgg cgatcatttt tatcgcgccg
     7621 ccagcatcgc agagcataag tacatgtctg ttatcttgtt tattgcagca cgattttttg
     7681 accagccatt ccattgcatt atcctgtttg ctaagagttt tcacatcaat ttacagatta
     7741 acagataaac tctttatcaa cggcaatgga atggcagaaa tgagaagtga aacggagggt
     7801 taattattgc tgacgttgca cccactcttt tagcgcctga cgtgaaattt taataccgcc
     7861 gtttttcagc tccggcggca gagttagcca gcgcaccggt tgttgaaaac gggccagctt
     7921 atctttcacc cattcactaa gatcaacgct ctcgtggtca tactccatca ccgccaccgg
     7981 tcgatgacca aactccttgt cggcaacggg gacgataaac acctgcaaaa ccgcaggatg
     8041 tgcagcaatt acgcgctcga cttcttccgg ctgaataccc tctccgccac tgaagaatag
     8101 attgtctaaa cgtccgacaa tggtcagctt gccattatgc atctcaccgc gatcgcgcgt
     8161 agcgtaccag ccttcgtcat taaccagtga aaccagttgc ccgttacgcc agtaaccttc
     8221 tgccatactg gcagcccgca gccacacttc attattaacg attttcactt cccgacccgg
     8281 cagcggcgaa ccaacgtctg ccaggccgtc ggcttctttc gcacacaccg tggaggcaaa
     8341 ctcggtcaga ccatagccgc aaaagcaacg aatcccctgc tcgcgcgcct gttccgtcaa
     8401 ctcgaccggg atagccgcgc cgccaagtaa caccgctttc agggaaacgg aactacggtt
     8461 aaccagcaaa cgccagagtt gtgttggcac cagtgaagcg tgagtacagc ctgccagcat
     8521 ttgctccaat ggctgtttat cacgtaccgt catccgcgca ccagcgtata accagcgcca
     8581 cataattccc tgaccggaga cgtgaaacag cggtaaagag agcaaccaat catcgtgatc
     8641 gccaaacgga atcagcgata acacaccttg cgcactggca agatgggcct gataagtatg
     8701 gacagcggct ttcggcaaac cggtagaacc cgaggtcaac gtcattgagc acagacgcgt
     8761 cggctgccac gtagcggcat gtgcgccttc aaccagctga atgtgcagcg acgttaatgc
     8821 cggaaacgtg ttttccccat ccggcaccag agcaaattgc agcgtcagat tgggcagcaa
     8881 ttcttcaagc aacggttgcg gcagctgagg gttcacgggc aacacccgcg ccccgcattg
     8941 cagtaacgcc agccaggcga gcagcgtttg cggcgtattc cacgcccgca acatcacgcc
     9001 gctgccctca accaccccct gcaccgcaaa tccggaggct aattcatcga cgcgagcaca
     9061 aagctcgcgc cagttgagtt gctcgtcatt aagacgtaag gcgatggttt ctccccgcac
     9121 ttgccgccag tgacgccacg gccagtcaga gaagatcata acaaccgctc cagtgcatca
     9181 acttccacga caggcagcgt gctacccggc cagcgacgta cctgctgcgc ctgcatcaga
     9241 tccagcgtgt ccagccctgg aatggtgtcc ggcgttaacc aggcggcaat ccgcgccagt
     9301 tgcgttaagc ctaagctcga ttcaatggaa gaactgatca ccgccgtcag ccccagcgcg
     9361 tgcgccgcct gtacctgctc gcgtactttt tccagactgc ccgtgagcgt gggtttgata
     9421 actaccgcgc gcacgccctc ttcagccaca aaggcaaaat ccggctcgcg caggctttca
     9481 tcccaggcaa tggcaatgcc ggtttcacgg gcaaacgctc gcgaatcatc gcgggttttg
     9541 cacggctctt cgagaaacgc gatgcggtcg cgataatccg ggttaacgta tttggcaaac
     9601 tgctgacctt tcagcggtgt ccaggcgcga tttgcgtcaa gacgcaaatg cagatccgga
     9661 attgcctcca gcaacagatt caccaccatg ccgtcgcgca ccgcttcgta caatcccact
     9721 ttgaccttcg ccactttctc gcctggcata tctgcaagtt tgaggatcag atcgtccgga
     9781 tcgccattac acagcggtgc cgcacggtag ttggctgctt gcggcaacgt atctgtcagt
     9841 tctgccaatg cacagcttac gccaaaggcc acggaaggca tctgcggtag ctcgcaatcg
     9901 cctgccagcc agttatttac ccaggcaagc agcacacttt gcgcctcttc ccaggtttcc
     9961 tgactgaagc ccggcagtgg ggagatctcc ccccaccctt cgcgctcgcc ttcacgcagg
    10021 caaacataca gcccgtcgcg ggtttttaac cgcctgtcgc gcagaaccac ccccgcgtcc
    10081 atggggatct gccagcggta tacctgcgcg ctacgcatta cggattccgt ttgaatttgc
    10141 tgaagtcagg ctgacgtttc tggttgaagg cgttgcgacc ttcctgacct tcttccgtca
    10201 tgtagaacag catggtggcg ttgcccgcca gctcctgcag ccccgcctgc ccgtcacagt
    10261 cggcgttcag tgcagctttc aggcagcgca gcgccatcgg gctgttttgc agcatttcgc
    10321 ggcaccaacg gacggtttct ttttccagat ccgccagcgg taccacggtg ttcacaaggc
    10381 ccatatccag cgcctgtttt gcgtcgtact gacggcacag gaaccagatt tcacgcgctt
    10441 ttttctgccc gacgatgcga gccatgtagg aagcgcccca gccgccgtcg aaggaaccga
    10501 ctttcgggcc agtctgaccg aagatggcat tatctgccgc gatagtcagg tcgcacatca
    10561 tgtgcagaac gtgaccgccg ccgatggagt agccagccac catcgcgaca accggtttcg
    10621 gacaggtacg gatctgacgc tggaagtcca gcacattcag gtgatgtacg ccggaatcat
    10681 ctttatagcc gccgtaatca ccacgcactt tctggtcacc accggagcag aacgctttat
    10741 cgcctgcacc agtcagaatg atcacgccga tgttgtcgtc ataacgcgca tctgccagcg
    10801 cctggatcat ctcttttacc gtcagaggac ggaaggcatt gcgcacctgc ggacgattaa
    10861 tggtgatttt tgcgataccg tcggtggatt tttcataacg aatgtcctcg aaaccttcgg
    10921 agcagtcgtg ccattcaacc ggtgcgtaaa gcattgcttc atcaggataa atcatattgt
    10981 gtcctttagt cagaaacgca agatctgcgc cagacttgcg attacgccag cgggattttc
    11041 ccgatgcgcg ttatgtccgg cgcgaggaat gacatggcag tcggcagcca gttccgccgc
    11101 cagggcgcgg aatttgctgt cacgttcacc acataaataa taaaacgcaa atgtgcgggc
    11161 gctaaggtta gcacgtaaat caggctggac ggcgagagaa gtcgcctcca gcatggcggc
    11221 aagcgttgcg ccattattgt tgctgcgcag cgccaccagc tcccggcgtt gatcgtcatt
    11281 gagtgaggca aaaacaggct gttgatacca gtcggcaaat accgccgtta acggttctgt
    11341 gagaaaacgc tgcacccatt ggcgatcgga acgctgacgt tccgcacgtt gttcagcatt
    11401 ttgcagcccc ggatgcccgc cttcgacaat aaccccacaa agccccgcca gcccctggca
    11461 agccgccatc atcgccaccc gtccaccaag cgagtacccc accagccaga agtcaaggat
    11521 gttgtaacta accaaggttt tacgcagtaa gtcggtgaca tcatcaaatc catcgacgct
    11581 aatcgccgcc gaaccaccgt gacctgggag atcaacatac aaccgtgagt agtcggcaaa
    11641 cgcctcgccc acttcttgcc attcgtggca atcgccggaa aaaccgtgca aaaacaccag
    11701 ccagggtaaa cctggttttc cgtgttttgc ctgcgcgtgc aggatcataa atggcttacc
    11761 tgcgccagaa gttgctggag cgtttgcgca ccatcggtgt cgttaaccac catttcaatc
    11821 accgtggtgg ttggcgtgcg ccaggcgtcg gcaaatgccg tttcaagttc ctgccagttt
    11881 tgcggacgat gatatttcag ctcgaacatc gcggcggcgt gctcaaaatg gacgttttgc
    11941 ggcatcagat agaaacgctc acgctcgctt tgcggcgttg gcaacagcga gaaaatttgc
    12001 ccgccgttgt tgttcaccac aattaatacc agcggcgcag aaacctgacg caataacgcc
    12061 agcgcgttga gatcgtaaag tgcggagaga tcgcccacaa tcgccagcgt cggtttgccg
    12121 cttgcccgct gaacgccggc ggcggtcgaa agcagcccgt cgataccgct ggccccacgg
    12181 ttgctgtaca ccgggtaacc tgccggaagt tgcgaaagcg catcaatcag acgtaccacc
    12241 aggctgttac caacaaacaa ttgcccctgt tcaggcagat agtcgcagat gcgatgcgcc
    12301 agttgcgctt cgccaaacgc atcacggcgg gcaataaccg cctgcattgc ctgttccgcc
    12361 aggcgcggga tttcaacgca ccagggctgg cgtttttctg ccggatgcag ctccagccag
    12421 tcggcaatat tggcaattaa gcgacgtccg cgatggtgtg ccggatcaag tcgcccttca
    12481 atgtcatcaa caatccagta ctcttctggt tcacagcttg cctgccattg caggagccgt
    12541 ttccccgtca ggctgcttcc cagttgcacc acaatttgcg cctgctgcag ctcgctggtc
    12601 gctttggcat tgcctaacca aagatcggca cacggcagcg gctgcccggt ttgtgacagc
    12661 acatcgccaa tcagcggcca gccaagagtt tgcgcccaca gggcaacttt tttgccctct
    12721 tccgcactca tgcgcccggc aaccaccacg ccgcgctttt gtcgccagaa gaaccagtcg
    12781 cgctgttttt cactttccag acgaggcgct tcacgcagcc acggtttgtc gtcctgccac
    12841 cagtcaccca gacgctgttg ccagctaagc ccggtatcgt ccatttcgcc atacagcggt
    12901 tcagcaaacg ggcagttgat atggactccc cccgcatgaa gcgtaccgag agcgtggtcg
    12961 atggtagaaa ccagccaacg tgcggggata tcctgggtcg ggcgcggcaa tgaaatactg
    13021 tgcgtggggt gagaggcgaa cattcccggc tggcgaattg cctgattcgc gccgcagtca
    13081 attagctccg gcgggcgatc ggcggttaag agaatcagtt tttctccggt taacccggct
    13141 tcaatcagtg ccggatagag atttgccacc gccgtgccgg aggtcacaat caccgccacc
    13201 ggctgcttgc tgactttcgc cagccccagc gccagatgcc ccaacccacg ctcatcgaaa
    13261 tgggtgtggt gaatgaatgc ggaattctcc gccgccgcta acgttaacgg tgtagaacgc
    13321 gagcctgggg cgatacagat gtgtctgacg ccgtgacgcg ttaatgcttc cagaatgacc
    13381 gccgcccagc gtcggttaaa tgcgcttact gacatgagtt tgtccggtat caatattgcg
    13441 gctaagtata aggagctaca aaaatagatt attgatatga atcggtaatg atgcgactca
    13501 ttactattcc atttgtaata aagtacgcag ccctgccgct ttgttgtcga tttcctgcca
    13561 ctcttgctcg gggtcggaac cacggacaat gcccgcgcca gcatataatc gcacgacatt
    13621 gccgctaatt tttgctgagc gcagggaaac gcagaattcg ctttgttgta atgagagata
    13681 gcccgcagaa ccggcgtacc attctcgggt gaacggttcg tgacgggcga taaactgtcg
    13741 cgccagatcg cgcggtaagc cagcaactgc tgccgttggc tgcaactgat gtaaacagat
    13801 cacatcatcc gctttgttga gtgaagtcca gatacagcgg cgaagatgct gcactttacg
    13861 cagacgcagt acctgcggcg gtaaaacatc cagcgtctgg gtatcggcct gtaatcgttg
    13921 acagatatct tccaccacca gcatgttctc gcgctggttt ttatcatccg ccatcagcca
    13981 ctctcctaac tgctgcgcct gcttatcatc aggattattt gctactgttc ccgccagcgc
    14041 ttcagtacgc agcgctttgt cacgccgccg ccataaccgt tccggtgaag agccaagaaa
    14101 agcattttcg ccatcaaagg ccatgtaaaa atggtagcaa ttcagattca gtcgacgact
    14161 ggcagccatc atcgccgccg cgttgaccgg acttgcgaaa tgcaggtcag ttgcccgagc
    14221 gagcaccact ttgtcgagct caccttcggc gatggttttc gttgccagtt cgattaattg
    14281 cgtccagccc gttttgtccg gccagtgttg ttctcgcgtg gtggttaaat gtaacccagg
    14341 caagggcttg atactcacca gtgtggcgat aaattctttt gcctgaatcg catcgtgctg
    14401 aagggagctt tcgctgaata gcgtcagccg cagcgtggct ttaccgccac agcgtcgcca
    14461 ttccaggcgg ggtaaaagta aattgccctg cgacgggtca aaagcattca gcccccaaat
    14521 gcgtaagtcg gcgtgttccg ggtgctggcg aagaaaacgt tgtgcctggt ccaacgacgt
    14581 aaaacgggta atcgcgccca ggacgacagc ttcttcatca ccattacgtt gttgccagta
    14641 gaattgcggg tatgtttgct gactggccag ccagctcaag gcatcaaaag cgtctttgag
    14701 agggaaagga atatcgataa cccgaatgcc gggtgtcgcc ggaatctctt gcgacaaatg
    14761 gcgcagtaga ttttccagcg ccgtagtaag tgattgcacg cggacctctc cctgttaaaa
    14821 gcctcacatt atacggggta ctacaaaaaa aatgcagtac cccggtgtag ggaggtttta
    14881 acgacgtgcc agcaacagtc ctagtaccag cccaacggcc gcgcccacac caattccttg
    14941 ccagggtttt tcgtggacgt agtcatcagc acgataaact gcctgcttcg cccgatagta
    15001 ataactgtct gaagcctggc taacccgttt tttcacatca tccagcgctt tttctgcacg
    15061 cgctttcagc tcaacatatt tctgatcggc gggatcgcca gaggagcgga gcacctcttc
    15121 cagtgtttca ctaagcagcg tcaggtcgtc atcgatacgt gtatcaccaa actgattaga
    15181 cattctcgtt ctccatttgc gtaaaacctg tcactaacta tagacaaggg ttgttgatta
    15241 cgcctgaatt acctcgcgtg ccatcccaat gtgtgggata ccatcttctt catagacctc
    15301 cgtcacaggg ataaaaccga aactctggta gaagttttgc agatgcgcct gcgccccgag
    15361 gtaaacaggc ttatcaggcc agtgatgcgt acatgtttcg agtgttttac tcatcagctg
    15421 ctgccccact ttttcgccac gcaacgcttc actgacaatc acccgaccta taacgaccgg
    15481 ctcaagatca tcatcacttt tcagaatcct cgcatacgcc accagttcat catttttcca
    15541 accgagaata tggcgattat cccccgtcaa atcatcacca tcgatatcct gataagggca
    15601 attctgctcg acaacaaaca ccgcgcaacg cagttgtaat aaggcataaa gctgggaaac
    15661 cgataattca gagtgatgca gatcttgcca ttcaatcata atgctctcct tttagatgta
    15721 tgccttatac tagccggaat attttttgaa acgtgatgaa ctcatggaat taattttttt
    15781 aggtacttca gccggtgtgc caacccgcac gcgcaatgtc acggcaatat tgcttaacct
    15841 gcaacatccg acccagagcg gactttggtt gtttgactgc ggtgaaggca cccagcatca
    15901 gctactgcat accgccttta accctggaaa actggacaag atttttatca gtcaccttca
    15961 tggcgatcat ctttttggtt tacccggctt gctgtgcagt cgttctatgt caggcattat
    16021 ccaaccctta acgatttatg gtccgcaagg tatccgtgaa tttgtggaaa ccgcgctgcg
    16081 gattagcggc tcatggaccg attatccgct ggaaattgtc gaaattggcg ctggcgaaat
    16141 tctcgatgat ggcctgcgca aagtaaccgc ttatccgctg gaacacccac tggaatgtta
    16201 tggctatcgt attgaagaac atgataaacc gggtgcatta aatgcccagg cattaaaagc
    16261 tgctggcgtg ccgcctggcc cactgtttca ggaattaaaa gcgggcaaaa caatcacgct
    16321 ggaagatgga aggcagatta acggcgcaga ttacttagct gctccagtgc caggtaaagc
    16381 gctcgctatt ttcggcgata ccggcccctg cgatgccgca cttgacctgg ctaaaggtgt
    16441 cgatgtcatg gtgcacgaag cgacgctgga tataaccatg gaagccaaag ccaatagtcg
    16501 cggccatagc tctacacgcc aggctgcgac actagcccgt gaggctggag tcggcaagct
    16561 aatcattacc cacgtcagct cgcgctatga tgacaaaggt tgtcagcacc tgttacgtga
    16621 atgcaggtca attttcccgg cgactgaact ggcgaatgat ttcaccgtgt ttaacgttta
    16681 actctgctta ttattaaaaa cagggcgaaa cttgccctgt tatcgcaacc cgcgctacat
    16741 atatccaccc acacaggcat attgagcgat ttttgatatt tattcatctc cttacgcact
    16801 atattcagag caataagttg cctcttttca tcttgattca gcacaacctt tgcaactaaa
    16861 aggagcccat gatggttaca gttgtcagca attattgtca attatctcaa acgcaactca
    16921 gtcagacatt tgcagaaaaa tttactgtga ccgaggaatt actgcagtct ttaaaaaaaa
    16981 cagcgttatc cggagatgaa gaaagcattg agttactgca taatattgcg ttaggttatg
    17041 ataaatttgg gaaagaagct gaagatattc tttaccatat tgttagaacc ccaacaaatg
    17101 agaccctatc gattatccga cttatcaaaa atgcttgttt aaaattatat aatctggcac
    17161 atatcgcaat caactccccc ctcaaatcac atgattcaga tgatctcctg ttcaaaaaac
    17221 tattctcccc ttcgaaatta atgacaatta tcggtgatga aattcctctt atatctgaaa
    17281 aacagtcgct ttcaaaggtg cttttaaatg atgagaataa tgaactgagt gatggtacaa
    17341 acttctggga taaaaatcgt caattaacca cagatgaaat agcttgctat cttcagaaga
    17401 tcgccgctaa tgcaaaaaat actcaagtca attatcctac tggtctctac gtcccctact
    17461 ccaccagaac tcacctggaa gacgctctca atgaaaatat taagagcgat ccatcatggc
    17521 cgaatgaagt ccagttattc cccataaata ctggcggaca ct
//
LOCUS       DAPHKZ010000094        17462 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.094, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000094 DAPHKZ010000000
VERSION     DAPHKZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17462
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.094"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(101..832)
                     /gene="rlmB"
                     /locus_tag="RH288_003270"
     CDS             complement(101..832)
                     /gene="rlmB"
                     /locus_tag="RH288_003270"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDV4032301.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRS"
     gene            complement(1012..3453)
                     /gene="rnr"
                     /locus_tag="RH288_003271"
     CDS             complement(1012..3453)
                     /gene="rnr"
                     /locus_tag="RH288_003271"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418600.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDV4032302.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVEL
                     HIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
                     GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPSTPLDREARNRGTSVYFPSQVIPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQG
                     DQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYY
                     RFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIA
                     AATKAKRAAKKKVAE"
     gene            complement(3492..3917)
                     /gene="nsrR"
                     /locus_tag="RH288_003272"
     CDS             complement(3492..3917)
                     /gene="nsrR"
                     /locus_tag="RH288_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HDV4032303.1"
                     /translation="MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVK
                     IINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(4122..5420)
                     /gene="purA"
                     /locus_tag="RH288_003273"
     CDS             complement(4122..5420)
                     /gene="purA"
                     /locus_tag="RH288_003273"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDV4032304.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(5524..5721)
                     /locus_tag="RH288_003274"
     CDS             complement(5524..5721)
                     /locus_tag="RH288_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HDV4032305.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMTNLPDNILRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(5803..6807)
                     /gene="hflC"
                     /locus_tag="RH288_003275"
     CDS             complement(5803..6807)
                     /gene="hflC"
                     /locus_tag="RH288_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HDV4032306.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNK
                     PLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
                     "
     gene            complement(6810..8069)
                     /gene="hflK"
                     /locus_tag="RH288_003276"
     CDS             complement(6810..8069)
                     /gene="hflK"
                     /locus_tag="RH288_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HDV4032307.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKV
                     LGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASN
                     TSSTSQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(8155..9435)
                     /gene="hflX"
                     /locus_tag="RH288_003277"
     CDS             complement(8155..9435)
                     /gene="hflX"
                     /locus_tag="RH288_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDV4032308.1"
                     /translation="MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQ
                     ATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEE
                     NKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI"
     gene            complement(9511..9819)
                     /gene="hfq"
                     /locus_tag="RH288_003278"
     CDS             complement(9511..9819)
                     /gene="hfq"
                     /locus_tag="RH288_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDV4032309.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
                     "
     gene            complement(9905..10855)
                     /gene="miaA"
                     /locus_tag="RH288_003279"
     CDS             complement(9905..10855)
                     /gene="miaA"
                     /locus_tag="RH288_003279"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDV4032310.1"
                     /translation="MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSA
                     LIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATR
                     QLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG"
     gene            complement(10848..12695)
                     /gene="mutL"
                     /locus_tag="RH288_003280"
     CDS             complement(10848..12695)
                     /gene="mutL"
                     /locus_tag="RH288_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDV4032311.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDI
                     DIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQQEAWQAYAEGRDMNVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     LRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGT
                     AFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQL
                     ETPLPLDDEPQPAPRSIPENRVAAGRNHFAEPAAREPVAPRYTPAPASGSRPAAPWPN
                     AQPGYQKQQGEVYRQLLQTPAPMQKLKAPEPQEPALAANSQSFGRVLTIVHSDCALLE
                     RDGNISLLSLPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSAEEKSALEKAQSALA
                     ELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLM
                     SEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE"
     gene            complement(12705..14042)
                     /gene="amiB"
                     /locus_tag="RH288_003281"
     CDS             complement(12705..14042)
                     /gene="amiB"
                     /locus_tag="RH288_003281"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HDV4032312.1"
                     /translation="MMYRIRNWLVATLLLLCTPVGAATLSDIQVSNGNQQARITLSFI
                     GDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDL
                     TENGKTEAVKRQNGSNYTVVFTINADVPPPPPPPPVVAKRVETPAVVAPRVSEPARNP
                     FKTESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNV
                     TIAIARKLRTLLNDDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNR
                     SATGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQSDPYLSQAVLDLQF
                     GHSQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEE
                     RLLASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN"
     gene            complement(14061..14522)
                     /gene="tsaE"
                     /locus_tag="RH288_003282"
     CDS             complement(14061..14522)
                     /gene="tsaE"
                     /locus_tag="RH288_003282"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDV4032313.1"
                     /translation="MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG"
     gene            complement(14494..16041)
                     /gene="nnr"
                     /locus_tag="RH288_003283"
     CDS             complement(14494..16041)
                     /gene="nnr"
                     /locus_tag="RH288_003283"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDV4032314.1"
                     /translation="MTDHTMKKNPVSIPHTVWYADDIRRGEREAADVLGLTLYELMLR
                     AGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLAKAVGIEVTLLAQESDKPLP
                     EEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLRQAPRESISQLIDHANSH
                     PAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLG
                     LDSWLAGQETKIQRFSAEQLSHWLKPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEA
                     ALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMDSLTESLEWADVVVIGPGLGQQE
                     WGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLHCAKRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKLSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHD
                     ESSNSAP"
     gene            16040..17179
                     /gene="queG"
                     /locus_tag="RH288_003284"
     CDS             16040..17179
                     /gene="queG"
                     /locus_tag="RH288_003284"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDV4032315.1"
                     /translation="MSEPLDLNQLAQKIKQWGLELGFQQVGITDTDLSESEPKLQAWL
                     DKQYHGEMDWMARHGMLRARPHELLPGTLRVISVRMNYLPANAAFASTLKNPKLGYVS
                     RYALGRDYHKLLRNRLKKLGEMIQQHCVSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLVDIPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGAIPEELRPLMGNRIYGCDDCQLICPWNRYSQLTTEEDFSPRKPLHAP
                     ELIELFAWSEEKFLKVTEGSAIRRIGHLRWLRNIAVALGNAPWDETILTALESRKGEH
                     PLLDEHIAWAIAQQIERRNACIVEVQLPKKQRLVRVIEKGLPRDA"
     gene            complement(17162..17215)
                     /locus_tag="RH288_003285"
     CDS             complement(17162..17215)
                     /locus_tag="RH288_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032316.1"
                     /translation="MRFYFYSQAVDESGVTR"
BASE COUNT         3964 a         4973 c         4381 g         4144 t
ORIGIN      
        1 aatattaata aaatgaatat ttgcaatacg taattatctt accagctata gacaaaaaaa
       61 aaccatccaa atctggatgg cttttcataa ttctgagaaa ttagctgcgc tggcgcaccg
      121 cttcaaataa gcaaattccg gtcgcaaccg aaacgttcag ggaagaaacg cttccagcca
      181 tcgggatgct gatcaactca tcgcaatgtt cacgagtcag gcgacgcata ccttcacctt
      241 ccgcacccat caccagcgcc aggcgtccgg tcattttgct ctgatagagt gtatgatccg
      301 cctcgcctgc cgtaccgacg atccagatat tctcttcctg caacatacgc atggtgcgcg
      361 caaggttagt cacccgaatc agcggaacgc tttctgccgc gccgcaggct acttttttcg
      421 ccgtagcgtt gagctgtgcg gagcgatctt tcggcacaat caccgcatga acgcctgcgg
      481 cgtccgcact acgcaggcac gcgccgaggt tgtgcggatc ggttacgccg tcgaggatca
      541 gcaggaacgg ttgatcgagc gaagcgatca gatccggcag atcgttttcc tgatactgac
      601 gtcctggctt cacgcgggcg ataatgccct gatgcacggc accgtcgctt ttctcgtcga
      661 gatattggcg gtttgccaac tggataacca cgccctgaga ctcaagggcg tgaatcagcg
      721 gtaacagacg tttatcttca cggcctttta aaataaagac ttcctgaaaa cgttcagggg
      781 cgcgctccag cagggcctgc actgcgtgga tgccgtaaat catttcgctc attaatgtac
      841 tcgttgttta cgttttgcct gatgcactac gtttatccgg cctacatgat ctctgcaata
      901 tattgaattt gcgtgattat gtaggccgga taaggcgttc acgccgcatc cggcatgaac
      961 aaagcgcatt ttgtcagcaa tctaaccctc ttcttttaaa gagggtattg atcactctgc
     1021 cacttttttc ttcgccgcac gcttcgcttt ggtcgctgca gctattttct gcgttttcgc
     1081 cgatggcttt ttcgcttttc tcgcgtcttt cttcgccgct ttcggcttcg tttttttctc
     1141 accgcggaag gcgctgtctg gctcaaagtt taccttttta ccgacctgac gacgcttgcc
     1201 gcctttttta cctgcatcgc cttttttcgc tttctcgcgc gccgttttac cgacgttgcg
     1261 cggtgcgcgt tcgctggaga tcaggctaaa gtcgattttg cgctcgtcca tattaaccgc
     1321 ttcgacgcga acttccacgc gatcgcccag gcgataagtc tggccgctgg attcccccat
     1381 caggcgttgc cctacctggt caaagcgata gtagtcattg tccagcgaag agacatggac
     1441 cagaccatca atgaacaagt cgtccagacg gacgaagaag ccaaagccag tgacgctgga
     1501 aattacgcct ttaaagacgt tacctacctg gtcgagcatg aagtcacact tcagccagtc
     1561 agccacatcg cgcgttgctt cgtcggcacg acgttccgcc atcgaacagt gctgacccag
     1621 ttgcagcatc tcttccatcg aataatggta gccgccggtt tcagtggtgt tgccctgatg
     1681 cccctgctct ttcgccagca gatatttaat ggcgcggtgc agcgtcaggt ctggataacg
     1741 acgaatcggc gaagtaaagt gcgcatagga ctgcaatgcc aggccaaagt gaccacggtt
     1801 ttctggatcg taaatcgcct gtttcatcga gcgcagcagc atggtttgca gcatttctgc
     1861 atcaggacga tcggcaaccg actccagcag ctccgcgtag tcacgcggtt ccggcttgtt
     1921 accgcccggc agttccagcc ccagctccgc cagcactgaa cggaaagagg taatcgcttc
     1981 ggtgctcggc ttgtcgtgaa tacggaacag tgccggttct ttcgctttct caacgaaacg
     2041 cgccgccgag atattcgcca gaatcatgca ctcttcaatt aatttgtgcg cgtcgttacg
     2101 ctgggtctgt tcgatacgtt caatacggcg ttcagcgttg aaaatgaact tcgcttcttc
     2161 gctctcaaat gagatcccac cgcgttcttc acgggcttta tccagcactt tatagaggtt
     2221 atgcaactct tcgagatgct taaccagcgg ggcgtactgc tcgcgcagat cctgatcgcc
     2281 ctgcagaata tgccagactt tggtgtaggt cagacgcgcg tgagagctca tcaccgcttc
     2341 gtagaatttg tagcccgtca ggcggccttt cgacgaaacc gtcatctcgc acaccataca
     2401 caggcggtct acctgcgggt tgagcgaaca caggccgtta gagagcactt ccggcagcat
     2461 cgggataacc tgcgaaggga agtacaccga cgtgccacgg ttacgcgctt ctctgtccag
     2521 cggcgttgac ggacgcacat agtagctgac gtcggcaatc gcgacccata aacgccagcc
     2581 gccgccgcgt tttttctcgc agtaaactgc atcgtcaaag tcacgggcgt cttcgccatc
     2641 aatggtgacc agcggtaaat cgcgcagatc aacacggccc gcttttgctt cttccggcac
     2701 ttcttctttc agcccggcaa cctgttgctc aacagcctgc ggccagatgt acggaatttc
     2761 atgggtacgc agagcgatat caaccgccat gccggtgccc atattgtcgc ccagcacttc
     2821 gacgatttta cccaccgctt tggtgcggcg agtcggacgc tgagtcagtt cgactacgac
     2881 cacaaagccc atccgcgcgc ccatgatctg atcgggcggg attaagatat cgaagctcag
     2941 acggctgtcg tcaggaacca caaagccgac gcccgcttcg gtaaagtagc gaccaacaat
     3001 ctggctggtt tttggcacca gtacgcggac aatacgcgct tcacgacgac ctttacggtc
     3061 agcacccagc ggctgagcca gcacctgatc gccatgaatg caggttttca tctgctcgct
     3121 ggagagatac aaatcatctt tacgcccttc aacccgcaga aagccgtagc catcacggtg
     3181 gccaataacg gtacctttca ccaggtcgag gcgttccggc agcgcatagc actgacgacg
     3241 agtgaagacc agttgaccat cgcgctccat cgcgcgcagg cggcgacgca ggccttcaag
     3301 ctgctcttcg ccttcaatgt gcagttctac cgccagctca tcacggctgg ccggtttttc
     3361 acgtttggtt aaatgttcga ggataaattc ccgactaggg atgggattcg cgtatttttc
     3421 agcttcgcgt tcctggaaag gatcttgtga catctcggtt cctccgttgt catctctgat
     3481 gaagattttc gtcactccac cagcaataat ttataaagcg gttgattctc ttcaaccaaa
     3541 tcggcaagcg tgtagttatc cagttccgta agaaaacttt gcacggcctt agaaagtgcc
     3601 tgtttcaacc tacaggcagg tgtaatgtgg caaaactcac tgctgcaatt caccagcgat
     3661 aagggctcca gctcgcgcac cacatcacca atacgtatcg cactcgccgg tttacccagg
     3721 cgaatgccgc cattttttcc acgaacagca gtcacgtagc cggcacgact aagttgattg
     3781 attattttga ccatatgatt acgggagacg ccgtagacgt cagtcacttc agaaatactg
     3841 gtcatccgcc cttctggcaa tgacgccatg tagatcagcg cacgtaatcc gtaatcagtg
     3901 aaactcgtta actgcacatc aacctcaaaa gggaaatcgg gaaaaaatac atttatattg
     3961 atgataaacc agccacaagc tgtgtcgcta atttatttca gttcggggaa ggaaaaaagc
     4021 gaggatttaa cactgtgtcg gatagcgtaa tggcttaccc gacacagcaa tgtatcacac
     4081 tgttcgcccg gcaggcaaaa tatctgccag gcgtaccaga attacgcgtc gaacgggtcg
     4141 cgcagaatca tggtttcagt acgatccgga ccggtagaga tgatatcgat cggcacacca
     4201 gtcagctctt caatacgctt gatatagttc agcgccgcct gcggcaggcc gctacgatct
     4261 ttcacgccga aggtggattc agaccagccc ggcatggttt cgtaaatcgg ctctacacct
     4321 ttccagtcgt cagctgccag cggagtggta gtcacttcgc gaccatccgg catacggtaa
     4381 gccacgcaga gtttaacctc tttcaggcca tccagaacgt ccagtttagt caggcagaag
     4441 ccagacaggg agttcagctg taccgcacga cgaacggcaa cggtgtccag ccagccggta
     4501 cgacgacgac gccccgtagt tgcgccgaat tcgttaccct gcttgcagag gaactcgcca
     4561 gtttcatcaa acagttcggt cgggaacgga cctgcaccta cacgagtgga gtaagctttg
     4621 aggataccca gaacgtaatc aacataacgc gggcccaggc cggaaccggt cgccacgcca
     4681 ccagcagtgg tgttggaaga agttacgtac ggataagtac cgtggtcgat atccagcagc
     4741 gtaccctgcg caccttcaaa catgacgaaa tcgccacgct gacgcgcctg gtcgagcagg
     4801 tcagaaacgt caaccaccat agaagtcagg atgtcggcaa cagccatcgt atcatccaga
     4861 actttctggt aatcaaccgc ttcagctttg tagtagttaa ccaactggaa gttgtgatat
     4921 tccatcactt ctttcagttt ttcagcgaag gtttctttgt cgaaaaggtc gccaacacgc
     4981 agaccgcgac gtgctacttt atcttcataa gcaggcccga taccacgacc ggtggtgccg
     5041 atcgctttcg cgccacgcgc tttctcacgc gcgttatcca gcgcaacgtg ataatcaagg
     5101 atcagcggac atgcttcaga cagcagcaga cgctcacgaa cggggatgcc acggtcttcc
     5161 agttctttca tctctttcat cagcgcggcc ggagacagca caacaccgtt accgatgatg
     5221 ctggttacat tctcgcggag aatacctgat ggaataagat ggagaacggt tttttcaccg
     5281 ttgattacga gagtatggcc tgcgttgtga ccgccctggt agcgtacaac atatttagcc
     5341 cgttcagtca gaagatcgac gatcttacct ttaccttcgt caccccattg ggtgcccagt
     5401 acgacgacgt tgttacccat ttttcaaaat caccgtttgc ttaaaaatgg attctaccat
     5461 cgctttttca gagttacagc actttttgca ctcaaaaatg acctcgatca gtctgttttt
     5521 tgttcagcca atcgttttcc tcaacatgta gtagaccaca acgcccgcaa ccacaagtcc
     5581 accgccaaaa cgacgtaaaa tattatcggg caaattggtc atcgcagaga tcatcttctt
     5641 ccatgccttc gggtaaagca tcggccctaa accttccagt accaaaacca gggcaagcgc
     5701 cagccagatt gtcgaattca ttcattatcc ttatagaaaa agaaaaccac cgacatccct
     5761 gaggatgcgg tggctttatt gacctgtacc gcagtcgtta tattaacgcg ttgcggaagt
     5821 cggcgtcttc atgtagcgga agaaatcgct atccgggctc atgaccatca cgtcctgatt
     5881 gccagagaag ctgttctcat aagcacgcag gctacggatg aatgcgtaga agtccggatc
     5941 tttactgaat gcatcagcaa acagtttggc tgcttcggca tcgccttcac cacgcatgat
     6001 gcggccctga cgctcagctt ctgccagcgt tctggtcact tcatagtcgg cagtcgcgcg
     6061 cagtttttcc gcttcttcct gaccttgtga acggtgacga cgcgctaccg cttcacgctc
     6121 ggcgcgcata cggttgtaga tcgcttcaga cacttcggtc ggcaggttga tctgcttgat
     6181 acgcacatcg acaacttcaa tacccagcgc cgccatactg ttcgggttga tgaccggaac
     6241 tttgcccttc gtctcagccg ttacgcgctc tgccgcttcg gcaatggcgt tatctgccgc
     6301 cggggtagta acttcatctt ctgtacccgc agaaccggag ttcagcgcgt cacgtacttc
     6361 gagggtcaga cgaccacggg aatcggtgac gatatctttc acgtccaggc gaccaatttc
     6421 agaacgcaga cggtcagaga acttacgttt caacagcact tccgcttgcg aaatgtcgcc
     6481 accacccgtt gccaggtagt aacggctgaa atcgctgatg cgccatttga tgtaagagtc
     6541 gacgatcagg tctttcttct ctttggtcac aaagcggtcg gcctggttgt ccatggtctg
     6601 aatacgtgcg tcgagcattt tcaccgtttc aatgaacggt atcttgaaat gcagacccgg
     6661 ctcataaacc agaggtttgt tgtcatcgtc acgcagtacc ttaccaaaac gcagcgtaat
     6721 accgcgctca ccttctttga cgacaaagac agacatgtaa agcactacca gcacgatgat
     6781 gataatcgcg ataactgact tacgcatcgt tattccccct gacgctggta gtcgttacgc
     6841 tgcgcgttgg cgcggcgttg gtccataata tcgccctgac tggtggacga cgtgttgctt
     6901 gctccactgg ttgtggagga agaggctggc ggcagacgca gcagattgct ggcaccgtta
     6961 tcgctcttcg ccgcaggggc gttaccacct ttcagcatct ggtctaacgg cagaaccatc
     7021 aggttgccac ctttatcgtt aaccagcact ttgcgggtgt tacccaacac tttttccatc
     7081 gtctcgatat acagacgctc gcgagtaatt tccggcgcgg ctttatattc cggcagaagt
     7141 ttagcaaagc gcgccacttc accctgagct tccaggatgg tctgggcctt gtacgcacgc
     7201 gcctcttcga ggatacgttg cgcctgaccg ttcgcacgcg gctgaacttc gttggtatac
     7261 gcttctgctt cacgaatgta ttgctgttcg ttttcacgcg cggcaatcgc atcgtcaaac
     7321 gccgctttta cttcttccgg cggacgagca gcctggaagt tgacgtccag cagcgtgata
     7381 cccatgtcat acggacgaat cgtctcttcc agttcgcgct gagtatcgct acgaatcacg
     7441 gtacgacctt ccgtcagaat gcggtccatg gtgtatttac cgataactcc acgcagggcg
     7501 ctgtcggtag cctgacgcag gctgtcatcc gggctggtca cgctatacag atatttttcc
     7561 ggattggtga cgcggtactg cacgttcatc tcaacgcgca ctacgttctc gtccgacgtc
     7621 agcatcacac cagaagcggc cagttcacgc acggcttcca cgttcaccgg tttgacttcg
     7681 tcgataaacg tcggtttcca gttcagaccc ggctcaacca gatggctgaa tttaccaaag
     7741 cgtgttacca cgccgcgttc ggcttcttta atggtataga aaccactggc cgcccagata
     7801 atgacaatcg ctgccgctgc gatggtaacg acacgaccgc caagctgcgg gcgcgggcct
     7861 tgcgatgaac tgccaccgcc agatccggtg cctttaccgc cgcccagacc accgagcttt
     7921 ttgctcagtt tgcggaagat atcatctaaa tcaggtggcc cttgatcgcg accgcctttg
     7981 tttccatttc cctcagagtt gccgccaggt ttgctgcttc cccacgggtc gcggtcttgt
     8041 ccgttattac cgggctgatt ccacgccatg tttgtgctcc atatttgtta tgcggtgatc
     8101 cctgttgtct ttcgacgcca gaggatatga ctccacgctt cagacgctac gccgttagat
     8161 caggtaatcg atcaacgccg gttcttgttt acagaggcga cgccagtcaa cgatcggcat
     8221 acgaacttgc agacttacgc tgccgtcctc ctccatccac tctttttcta ttgcctgaag
     8281 ctgataaaaa cgacttctca gacgcccttc ctgcggtggc agacgcaatg tatgctgcgc
     8341 cacctcgccg gaaagccgct ccgtcaaagc ctgaaaaagc tgtggtatcc ccgctccggt
     8401 ctgtgcggaa agccagacac ggatcggttt gttctcttca tcccgatcaa tacgcggttc
     8461 gaaatcttcc agcatatcga tcttgttcat caccagcagg gttgggatct cgtgagcgtc
     8521 gatctcttca agaaccgtat tcaccgcttc gatgttttct tgtacacgca catccgccgc
     8581 atcaatgacg tgcagcagta atgtggcttg ccgcgtctct tgtaacgtgg ctttaaatgc
     8641 cgccaccaga tcgtgcggca ggtggcgaat aaaccctacg gtatctgcaa gtacggtttc
     8701 accgacatct gcaacgtcaa tacgccgcaa cgtcgggtcg agggtggcaa acaactggtc
     8761 tgccgcgtag acccgcgctt cggtgatgcg attgaaaagg gtagatttac cggcgttggt
     8821 atatcccacc agcgaaacag taggaacgtc ggctttgata cgcgattgcc gcccctgctc
     8881 acgctgcttt tcaactcttt ccaggcgcga ctgtatctgc acgatgcgat tacgcaacaa
     8941 acgacggtcg gtttcgagct gggtttcacc cggaccacgc aaacctatcc cgcctttctg
     9001 tctttcaagg tgggtccagc cacgcaccag gcgcgtagcc agatggcgca gctgcgccag
     9061 ctcaacctgc aacttaccct catgggtacg cgcacgttgg gcgaaaatat ctaaaataag
     9121 gccggtgcgg tcgataacac gacactcgca caaacgctcc aggttacgct cttgcgccgg
     9181 gctcagggca tggtcaaaaa gaacgaccga agcacccgtc gctttgacag cttccgcaat
     9241 ttcaactgct ttaccttcac ctacaaaata ctttgggtgc ggcgctttac ggctaccggt
     9301 aatcacctgc aatgcttcga caccggcgga agagaccaga gattcaaact cctggaggtc
     9361 ttccatatct ttgtcttgcg taaaatagat gtgtaccagt accgcctgct caccagcatc
     9421 ataacggtca aacaagcgta taaccctcta aatagatcag cggggaacgc aggatcgctg
     9481 gctccccgtg taaaaaaaca gcccgaaacc ttattcggtt tcttcgctgt cctgttgcgc
     9541 ggaagtattc tgcgcgctgc taccatgatg gtagttactg ctggtaccgc caccggcgtt
     9601 gttactgtga tgagaaaccg ggcgagacgg gacaacagta gaaatcgcgt gcttgtaaac
     9661 catctggctg accgtgtttt tcaacaggat cacgaactga tcaaaagact cgatttgccc
     9721 ttgcagctta ataccattca ccaaataaat agaaactgga acacgttccc gacgcagtgc
     9781 gttcaggaac ggatcttgta aagattgccc cttagccatt ctctcttttc cttatatgct
     9841 tatttgtact ttgaaccttt cgattctgaa aaaattgcgc acgatacgtc tcaattgtac
     9901 acattcagcc tgcgatagca ccaacaacct gtaatacttc gtcacgcgcc tgttctggtt
     9961 tttcactgtc aagccagtga accccttccc aaccacgcag ccaggttatc tgccgcttcg
    10021 ccaactgtct cgtggcgcaa acacctcgat aaaccatttc atcgtatgag atttcgcctt
    10081 caaggtaaga ccacatctgg cgataaccca cgcaacgaat ggaaggcaag tccgtatgca
    10141 aatctcctcg ggcaaaaagc gcccggactt ctgcttcaaa acctgaagcc aacatctgat
    10201 gaaaacgctg ctcaatgcgt tgatggagca gttcacggct cgccggggcg atggcgaact
    10261 gatgcacctg atacggtaga gcgtctcctg acgtttgcgt cagttccgtt aaagttttac
    10321 ccgaaatgaa aaaaacttcc agtgcccggg aaagcctttg tggatcattt ggatgaatcc
    10381 ttgctgccgc aaccggatct acctcctgaa gttgacgatg caatgactcc caaccttgct
    10441 ctgccgcctg ttgctcaatt ctggcccgta cttccgggtc tgccgacggt agcggcgaca
    10501 acccttccag caatgccttg aaatacaaca tcgtaccgcc cactaacagt gggatccgcc
    10561 ccgccgcggt gatatcggcc atttccgcca gcgcatcgcg gcgaaaatca gcagccgagt
    10621 aagcctgcga cggatcgcga atatccagca atcggtgcgg cgcggcgagt aactcttcag
    10681 cgttcggctt cgccgtcccg atatccatcc ctttgtaaat aagggcagaa tcaacgctta
    10741 tcaactctac tggtaaaatt ttacgcagct caatggctaa cgccgtttta ccggaggccg
    10801 tcggccccat caaaaaaatc gccttaggca ggctcgcctt actgatatca ctcatctttc
    10861 agggctttta tcgccggatg taaatcaaca gattgtaaca gaccacccgg cggcgttttc
    10921 acaagttgcg gacataaccg ttccacgtcc gccagcaggg ttatggcctg tgccattgac
    10981 cactgcgcat gttcgctcat cagatttcgt gcaatccact gcgcaatatt gccaggttcg
    11041 aatacggact gcttcgccag gtagcctatc agttcaggaa tcaagatttg taaattttgt
    11101 tggcgtaagg gtaaaggcac tgccctgatg gtcacatgct gtgcatctga ctggaaatca
    11161 atacccaatt ccgccagggc agactgcgct ttttctaatg ccgatttttc ttcggcagaa
    11221 acttttagcc gcaacggaat cagcagcggc tgggcgcaaa cgggcgcttc acccggcgtc
    11281 aattgtgcct gacgcagcca acgttctgcc actggcaagg ataaaagtga aatgttgccg
    11341 tcgcgctcca gcaacgcaca gtcggaatgg acgatagtca gtacccgacc aaaactctga
    11401 ctgttcgccg caagtgcagg ttcctgcggt tccggcgctt ttaatttttg catcggcgcg
    11461 ggcgtttgca aaagctggcg atacacttca ccttgctgtt tctggtagcc tggctgcgca
    11521 ttcggccagg gggcagccgg acgactgcct gatgctggcg caggagtgta gcgcggagct
    11581 accggctcac gagctgccgg ttctgcaaag tgattgcgcc ccgccgccac gcggttttcc
    11641 ggaatggaac gcggtgcagg ttggggttca tcgtccagcg gtagcggcgt ttccagttgc
    11701 tgttgtagca cgctcagcac gccctgatag ataaaatcat gcaccagacg cgactgatgg
    11761 aaacgcactt cgtgtttggc ggggtgcacg ttgacgtcca cctgatgtgg gtcgatctcc
    11821 agatacaaca caaatgccgg ttgctgatcg gcccccagtt tgtcttcgca ggcctggcgg
    11881 atcgcgtgat tgatcaggcg atcgcgcatc atgcgaccgt tcacgtagca atactgaatt
    11941 tctgccagtg cgggcgtggt gtgatttgga tcggccaccc agccgcgtag cgtgagatcg
    12001 ccgtgttgcc attcaatcgc cagcgcttgt tcaagaaaag cggtgccgca aatcgcgcct
    12061 aagcgccgtt ctttttgccc gccttccggc actgcgcggt actgacgcac aattttaccg
    12121 ttatgcgaca ggttgatcgt gacgtcgaaa cgcgccagcg caatgcggcg gatgatctca
    12181 tcaatgtggt taaattcggt tttctcggtg cgcaggaatt tgcgccgcgc cggggtgttg
    12241 tagaacagat ccagcacctc cagcgtcgtc cccacaggat gcgccgccgg ttttaccgtc
    12301 acgttcatat cgcgcccttc ggcataggcc tgccaggctt cctgctgttc tgcggtgcgt
    12361 gaagtgagcg tcaggcggga aaccgaactg atactcgcca gcgcctcacc gcgaaagccc
    12421 aggctgataa tggcttcgag atcgtccaga gaggcgattt tactggtggc atgacgagcc
    12481 agcgccagcg ccagctcatc ttttttgata ccgcagccgt tatcacgaat gcggataagt
    12541 ttcgccccac cgcgttcgat atcaatatcg atacgcgtcg cacctgcatc gaggctgttt
    12601 tccactagtt ctttgactac cgacgcaggt cgctcgacca cctcacctgc ggcaatctgg
    12661 ttcgccagtt gtggcggtaa gacctgaatt ggcatcaatc gtccttagtt tggcagcgtg
    12721 cgatctggcg tcgtcaccgt actggcagtt tgtgccgttg caccctgcgg cgcagattgc
    12781 atcggatgcg caaggaagta attgcgcagg cctttgtaaa tggcttctgc cagctgttgt
    12841 tggtaatcgt cgctcgccag caaacgttct tcgctgttgt tgctgataaa accggtttcg
    12901 accagtactg atgggatatc cggcgagcgc agaacgccaa ggctggcgtg ttctggtcga
    12961 cgtttatgta tttcgccaat gcgttgcaac tgactgatca tactggtcgc tacatcatac
    13021 cctacccgct gggaatgacc gaactgtaaa tccagcaccg cctggcttaa ataggggtca
    13081 gactgactgt tcgccagcac atcacccgcc ccacccagca gctccgactg tttctcgtgc
    13141 tgctccagcc agctggccat ttcactgttg gcgcgacggt tagagagcac ccatacggaa
    13201 gcgccagtcg cactgcggtt cggtgcggca tcagcgtgaa tcgacacgag gaaattggcg
    13261 ttttgcttac gtgccacatc actgcgcccc atcaccgaga taaagtaatc cccgtcacgg
    13321 gttaaaacgc ctttaaacat cggatcgtca ttgagcaaag tacgcaattt acgcgcgatg
    13381 gcgatggtga catttttctc ccgcgtacca ccggggccga tagcgccagg gtcctgaccg
    13441 ccgtgtccgg catcaatagc gatgataatt ttatcgccag tgttagccgt cgcgcgcgct
    13501 gccggacgcg ttaccgtatt actgctgata acacccgtag tgcggttact ttccgtttta
    13561 aacggattgc gcgccggttc gctgacgcgc ggtgcgacaa ccgcaggcgt ttcaacgcgt
    13621 ttcgcaacca cgggcggcgg aggaggcggt ggcggcacat cggcgttaat cgtaaagacg
    13681 acagtgtaat tgctgccatt ctgccgcttc accgcttcgg ttttaccgtt ttcggtaaga
    13741 tcgaccacca gccgtagcgt ttgtgcatct ttaggcgttc cagagcgaat cgccttcacc
    13801 agattattgc cgctgaacaa caacggcagt ccctgaatca cgcccgtttg tttgatatcg
    13861 agcgccacgg tgcgtttgct ttgatggcta aacgcataat caggatcgcc aataaaactc
    13921 aacgttatcc gcgcctgttg attaccgtta gaaacctgaa tatcagagag cgtcgcggca
    13981 cccaccggcg tgcacagcag cagcagcgtc gctaccaacc aatttctgat gcgatacatc
    14041 atcccgccac ctttcaaagg ttaaccggct aaacgcgcca gcaacaattc acccgcagag
    14101 gaaaccgcac tcacgcgcgc ctcacggcct tgtgcctgat aatcaatgtg tatttcgaca
    14161 tccgggtcag gaagaacacc tgtaccttgt tgtggccact ccaccaggca gatggcatcg
    14221 ttggcaaaat aatcgcggat ccccataaac tccagctcct cgggatcggc aaggcggtac
    14281 aaatcaaagt gatagaccat taagttgtcg agcgtatagg gttcgaccag cgtataagtg
    14341 gggcttttga cattaccctg atgacccaga gcctgtaaaa agccccggct aaaggtggtt
    14401 ttacctgcgc ctaaatcgcc atacagatag attacggttg cgccatcgca ggctttcgct
    14461 acccgctcgc ccaggtctaa tgttgcctgc tcatcaggga gcggaattac tcgattcatc
    14521 atggttttta tcagtcactt ccgggttaac aatacgctgt agcgtggaaa agagatcggt
    14581 tgccagcatc ccgcgcgttc caaaacgcgc cgccagtacg tcagctgccg caccgtgcgc
    14641 gacacagcct gcacaggctg catcatacgg cgacagtttt tgcccaagca atgcgccaat
    14701 aataccagag agcacatcgc ccatgccgcc gctcgccatg cctgcatttc cggcatcaat
    14761 aatgcctaaa gcgtcaggat gggcggcgac cacggttccg gcacctttca gcaccgctac
    14821 gccgccataa cgttgtacca gacgtttggc gcaatgtaag cggtcacttt caatttcagc
    14881 gacggaacag cctaacaacc gtgcggcctc gccaggatgc ggcgtgatca cgcgattgtg
    14941 acgcttatcg ggattgattg ccagcaggtt caatgcatcg gcatcccaca acatcggttt
    15001 gcgaaaattc tcaacttttt gcagtgcttt tttcccccac tcttgctggc ccagaccggg
    15061 accaatcacc accacatcgg cccattccag gctttcggta agagagtcca tcgtcagttc
    15121 atgcaccatc aattccggtc gtgcagtcag cagcggcgca atgttttcac tgcgggtcag
    15181 tactcggact aaaccagcac cagcacgcag cgccgcttcc cccgtcatac gaatagcccc
    15241 cgccgtgccg tgatcgccac cgataattac cagccgcccg tgatcgcctt tatgcgaagt
    15301 cgggcgacgc ggttttagcc agtgagaaag ttgttctgct gaaaaccgct gaattttcgt
    15361 ctcctgacct gccagccaac tatccagccc cagtgagtca aaatgcagtt gtccggtaac
    15421 atcccgcgct tttccagtga gcaagcctgg tttcagcgca ataaaagtga tggtgtgatc
    15481 ggcgttgatc accgcgcctg gcgtagcgcc agtttcagcc agcaggccgg aagggatatc
    15541 aaccgccaca atcggcgcag gatgggaatt agcgtggtcg attaactggc taatggattc
    15601 gcggggcgct tgccgcaaac cggtaccgag cagcgcatca acaatcagat ctaccgattc
    15661 gggccagaca atattcgaag catggatctc gccacccgcg tttaaccatg cttcgcgtgc
    15721 cagcgcggcc tcttccggca acggtttgtc gctctcctgg gccaacaacg tgacctcaat
    15781 gccgaccgct ttggccagtc gcgcgaccac gtagccatcg ccgccgttat taccatgacc
    15841 gcacagcacc agccagtggc gggcgtcagg atacgccgaa cgacacacct ggaatgcggc
    15901 ctcgccagcg cgaagcatca gctcatagag tgtgagcccc agcacatctg ccgcctcgcg
    15961 ttctccgcgg cggatatcgt cggcgtacca gacggtgtgt ggtatactta cggggttttt
    16021 cttcattgta tggtccgtca tgtcagagcc cctcgatctc aatcagttag cgcaaaaaat
    16081 taaacagtgg gggctggaac tgggctttca gcaggtaggt attaccgata ccgatctcag
    16141 cgagtccgag cccaaactgc aagcatggct ggacaaacaa taccacggcg aaatggactg
    16201 gatggcacgt cacggtatgc tgcgcgctcg ccctcatgag ttattgcccg gtacgctgcg
    16261 cgtgatcagc gtgcggatga attaccttcc tgctaacgcc gcatttgcca gcacgctgaa
    16321 aaaccccaaa ctcggctatg ttagccgtta tgcgctgggc cgtgactatc acaaacttct
    16381 gcgcaaccga ctcaaaaagc tgggcgagat gattcagcaa cattgtgttt cgctgaattt
    16441 tagaccgttt gtcgattctg cgcctattct cgagcgcccg ttagctgaaa aagctgggct
    16501 cggctggaca ggtaagcact cacttatcct caatcgcgag gccggttcgt tcttcttttt
    16561 aggcgaattg ctggtcgata ttccgctgcc cgtggatcaa ccagtcgagg aaggatgcgg
    16621 caaatgcgtg gcctgtatga cgatttgccc gaccggtgcc atcgtcgagc catataccgt
    16681 cgatgctcgc cgctgtatct cttatctcac catcgaactt gaaggggcga tcccggaaga
    16741 gttgcgaccg ttaatgggaa accgtattta cggttgcgat gactgccagc ttatctgccc
    16801 gtggaatcgc tattcacaac tcaccacaga agaggatttc agcccgcgta agccgctaca
    16861 cgcaccggaa ctcattgagt tattcgcctg gagcgaagag aagtttttaa aagtcacgga
    16921 aggatcggcg attcgtcgta ttggtcacct gcgttggctg cgtaatatcg ccgtagcatt
    16981 aggcaatgcc ccttgggatg aaacgatttt gacagcgctg gaaagtcgta aaggtgagca
    17041 cccacttctc gatgagcaca tagcgtgggc gattgcgcag caaatagaga gacgaaatgc
    17101 gtgcatagtc gaagtgcaat tgccgaaaaa acagcgtctg gttcgggtga ttgaaaaagg
    17161 gttaccgcgt gacgcctgat tcatccacag cttgtgaata aaaataaaaa cgcattgcaa
    17221 ttcaagacga ataaaatcgt caagtgatcg actcgacaaa atggaatctt aatttttaac
    17281 ttatctatca ataggttaaa aaaatactat tcaccgtgcg aagtttcttt gaaattaaga
    17341 ttacagcctg aggctgtgga taactctgtt tacaagagtt tgtcagagac aacaaaaacc
    17401 agcaataacg catcgcgtcg ctgtggatat tttattgaga gaagaatttg gagcgggaaa
    17461 cg
//
LOCUS       DAPHKZ010000095        17288 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.095, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000095 DAPHKZ010000000
VERSION     DAPHKZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17288
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.095"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            107..568
                     /locus_tag="RH288_003286"
     CDS             107..568
                     /locus_tag="RH288_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegJ family protein"
                     /protein_id="HDV4032317.1"
                     /translation="MKKILLMLSLLFFTTAGFSEVSDTLVTGGYDKQAMSDAIKHARK
                     ETDKFIEVMNKKDADTFAVKAPITDHGRTEHFWLTDVTYSNGMFIGVISNDPSIVTNV
                     EYGQEWKIKKEDISDWMYTRGDKIYGGYTIDPLLVTYPKEEADELRAKLVR"
     gene            complement(633..1394)
                     /gene="pphC"
                     /locus_tag="RH288_003287"
     CDS             complement(633..1394)
                     /gene="pphC"
                     /locus_tag="RH288_003287"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase PphC"
                     /protein_id="HDV4032318.1"
                     /translation="MSWRLVYASAVGTSHISADLPCQDACQMQVAWLNDQQPLLVMFL
                     ADGAGSVSQGGEGAMLAVNEAMAYMSQKVQGGELGLNDILATDIVLTIRQRLFAEAEA
                     KELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDFGHGLQLPLTPMVGEYANMTHFI
                     TDEDAVSRLETFTSTERVHKVAAFTDGIQRLALNMLDNSPHVPFFTPFFNGLASATQE
                     QLDLLPELLKQFLSSPAVNERTDDDKTLALALWAE"
     gene            complement(1391..2050)
                     /locus_tag="RH288_003288"
     CDS             complement(1391..2050)
                     /locus_tag="RH288_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDV4032319.1"
                     /translation="MSEQITFATSDFASNPEPRCPCILLLDVSGSMSGRPINELNAGL
                     VTFRDELLADSLALKRVELGIVTFGPVHVEQPFTSAANFFPPILFAQGDTPMGAAITK
                     ALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFQGEEDKKFAFFSIA
                     VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTS
                     V"
     gene            complement(2271..2330)
                     /gene="ibsA"
                     /locus_tag="RH288_003289"
     CDS             complement(2271..2330)
                     /gene="ibsA"
                     /locus_tag="RH288_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsA"
                     /protein_id="HDV4032320.1"
                     /translation="MMKHVIILVILLVISFQAY"
     gene            complement(2603..2659)
                     /locus_tag="RH288_003290"
     CDS             complement(2603..2659)
                     /locus_tag="RH288_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDV4032321.1"
                     /translation="MMKLLIIVVLLVISFPAY"
     gene            2938..4185
                     /gene="mdtA"
                     /locus_tag="RH288_003291"
     CDS             2938..4185
                     /gene="mdtA"
                     /locus_tag="RH288_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HDV4032322.1"
                     /translation="MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQ
                     QSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLMALH
                     FQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLV
                     SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQIS
                     SGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTL
                     LSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNE
                     GHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVE
                     AQSATTPEEKATSREYAKKGARS"
     gene            4185..7307
                     /gene="mdtB"
                     /locus_tag="RH288_003292"
     CDS             4185..7307
                     /gene="mdtB"
                     /locus_tag="RH288_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HDV4032323.1"
                     /translation="MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVS
                     ALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
                     TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAIT
                     GANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAE
                     NSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQN
                     RFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQD
                     NGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQ
                     INLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQAT
                     SLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKI
                     EQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGST
                     LAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGS
                     ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK
                     SRFARHEEEA"
     gene            7308..10385
                     /gene="mdtC"
                     /locus_tag="RH288_003293"
     CDS             7308..10385
                     /gene="mdtC"
                     /locus_tag="RH288_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HDV4032324.1"
                     /translation="MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDIN
                     GAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
                     QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG
                     ALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRSSLEEV
                     EQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRML
                     VALQQGYGKSLNWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQ
                     QIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRK
                     KLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGL
                     SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILI
                     IAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE"
     gene            10386..11801
                     /locus_tag="RH288_003294"
     CDS             10386..11801
                     /locus_tag="RH288_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4032325.1"
                     /translation="MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESP
                     LHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELL
                     LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
                     ASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSK
                     GTGLSPLAITGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATT
                     LGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNS
                     LLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMALIIALPAFIF
                     ARVPNDTHQNVAISRRKRSAQ"
     gene            11798..13201
                     /gene="baeS"
                     /locus_tag="RH288_003295"
     CDS             11798..13201
                     /gene="baeS"
                     /locus_tag="RH288_003295"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HDV4032326.1"
                     /translation="MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIK
                     HGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHG
                     WRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
                     KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSED
                     ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPE
                     TVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASRG
                     LKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFAD
                     SAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGG
                     VSITVELPLERDLQREV"
     gene            13198..13920
                     /gene="baeR"
                     /locus_tag="RH288_003296"
     CDS             13198..13920
                     /gene="baeR"
                     /locus_tag="RH288_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HDV4032327.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGD
                     QVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
                     LTPAEFRLLKTLSHEPGKVFSREHLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRIV"
     gene            14111..14443
                     /locus_tag="RH288_003297"
     CDS             14111..14443
                     /locus_tag="RH288_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HDV4032328.1"
                     /translation="MAGWFELSKSSDNQFRFVLKAGNGETILTSELYTSKASAEKGIA
                     SVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGSSQMYATAQSRETGIASVKANGT
                     SQTVKDNT"
     gene            14652..14948
                     /locus_tag="RH288_003298"
     CDS             14652..14948
                     /locus_tag="RH288_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001307279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /protein_id="HDV4032329.1"
                     /translation="MTYTDVRFLLTGGRKMARTMTVDLGDELREFIESLIESGDYRTQ
                     SEVIRESLRLLREKQAESRLQALRDMLAEGLSSGEAQPWEKDAFLRKVKAGIRK"
     gene            14950..15246
                     /locus_tag="RH288_003299"
     CDS             14950..15246
                     /locus_tag="RH288_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDV4032330.1"
                     /translation="MRIIKLMPKANEDLEGIWYYSYHHFGEPQADRYVEHLSDVLQIL
                     SNNNIGTPRPELGEGIFVLPFERHVIYFLQSPGEIIVIRILNQNQDATRHLHWS"
     gene            15349..16710
                     /gene="yegQ"
                     /locus_tag="RH288_003300"
     CDS             15349..16710
                     /gene="yegQ"
                     /locus_tag="RH288_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HDV4032331.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKY
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEHMENAKGEAMPVAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNP
                     HGK"
     gene            complement(17041..>17288)
                     /locus_tag="RH288_003301"
     CDS             complement(17041..>17288)
                     /locus_tag="RH288_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032332.1"
                     /translation="TSIGKFGLAYKSNIQRKLDNQYYTEAEASLARGRISGAENIVKN
                     DATHFCVTQGKKMQIVELKTEGVGLHGVARLTFKCGE"
BASE COUNT         4024 a         4579 c         4577 g         4108 t
ORIGIN      
        1 aaaatgataa tgtaatttca tcaggataca attcaattcc aacctgataa tgattcactt
       61 ccacaggttt tgctaacttt tactacacag agattctgga gaaaaaatga aaaagatatt
      121 actcatgttg agcctgctat tttttactac cgcgggcttt agtgaagttt cggatacgtt
      181 agtgacagga ggttatgata aacaagcgat gtctgacgcg attaaacatg cgcggaaaga
      241 aactgataaa ttcatcgagg ttatgaataa aaaagatgcc gatactttcg cagtcaaagc
      301 cccgataacc gatcacggaa gaaccgagca tttctggctc acggatgtca cttattctaa
      361 cggcatgttt attggcgtaa tcagcaatga ccctagtatt gttacaaacg tagaatatgg
      421 ccaggagtgg aaaatcaaga aagaagatat ttcagactgg atgtatacgc gcggggataa
      481 aatttacggc ggttatacca ttgatccttt attggtcacc tatccaaaag aagaagccga
      541 cgagcttaga gcaaaattag ttcgctaatc agccgttata tttattgttt aaactggcgg
      601 ttgaattgtt gtcttcaacc gccatgagaa actcactctg cccacagcgc cagtgctaac
      661 gttttatcat catcggtacg ctcgtttacc gctgggctgg acaaaaactg ctttaacaat
      721 tcaggtaata aatcgagttg ttcctgcgtt gctgacgcca gtccattgaa aaacggggta
      781 aagaaaggca catgcggaga attatccaac atatttaacg ccagtcgctg gataccatcc
      841 gtaaatgctg caactttatg cacacgctca gtgctggtga aagtttccag tctggaaacg
      901 gcatcttcat cggtaatgaa gtgcgtcata ttggcatatt cacccaccat cggcgtaagc
      961 ggcaattgca gaccgtgacc aaaatccacc accacgccgc catcgccaat ctgcataatc
     1021 aaggtgccat tagccgatga aatcaatccc agaaacgtgc aggcaaaatc gcgaaccgct
     1081 aattctttgg cctctgcctc ggcaaaaagt cgctgacgaa tagtcagcac aatatccgtg
     1141 gcgaggatat cattaagccc caattcccca ccctgcactt tttgcgacat ataagccatc
     1201 gcttcattga cggcgagcat cgcgccttcg ccaccctgcg agacgctgcc tgcaccatca
     1261 gcaagaaaca tcaccagtaa tggttgctga tcgtttaacc aggcaacctg catctggcag
     1321 gcatcctgac aaggtaaatc agcgctaatg tgcgacgttc caacagcgga tgcataaacc
     1381 agacgccagc tcacactgac gtccagcctt ttggcgcttc cagcacaact tccgttcccg
     1441 gcgtggagcg ggaaaccgaa cgcagcgaac tggataacca gctaaacagt tcacggaatt
     1501 gtaatccttg cagaggcaaa ggctgacgaa cgctgatttg tgccagcgtc ttcatatccg
     1561 ccccctgaac agcgatggaa aagaaggcaa acttcttatc ttcttccccc tgaaacactt
     1621 tgttggcggc agcctgccac tcatcggttg gagcgccatc ggtgatcagg aaaatccacg
     1681 ggcgataata cgaaatacca tttgcgcggt actcacgttt cctctcttca accatatcca
     1741 gggctttggt aatggcggcc cccattggcg tatccccctg ggcaaacagg atgggcggga
     1801 aaaagttagc ggcgctggta aagggttgtt ccacatgcac cgggccgaac gtcacaatac
     1861 cgagttccac tctttttaag gccagcgaat cggcaagcag ctcatcgcga aaggtaacca
     1921 atccggcgtt aagttcatta atgggtctgc cgctcatcga gccagaaaca tccagcagca
     1981 aaatgcaggg gcaacgtggt tccgggttac tggcaaaatc gctggtggca aacgtgattt
     2041 gttcgctcat aagaaatcct ttcttagaga attattgagg tccggtatca taccgactgc
     2101 aataatgaaa taagagcaaa cgaagaaact ttcagaatta ggcccggcgg cgcagaaaat
     2161 tttgctattc gcctcgcaag aacggagagc cgtcgattga cactaagggc ggagtgacat
     2221 aatttcagga gtgagggtta gggagaggtt tccccctccc cctggtgttc ttagtaagcc
     2281 tggaagctaa tcactaagag tatcaccagt atgatgacgt gcttcatcat aaccctttcc
     2341 ttattaaaag ccctcttctc cgggagaggc tttcccgttt cagcgtcccg ctgaaatcat
     2401 cggcttacct cctttcgccc tgaatgcagt ctatcgctaa cgcgtgaata aaatagtttc
     2461 ctctgtgatt attgcgtaac gactcgcaaa gaatatttgc tggcaggatc gcagactaca
     2521 aagcctgcgg attgacaatc ttatcgtgaa ggcatacttt caggagtgag ggtagagcgg
     2581 ggtttccccc gccctggtag tcttagtaag cggggaagct tatgactaag agcaccacga
     2641 tgatgagtag cttcatcatg accctttcct tatttaaggc cccttcctcg ggaggggctt
     2701 tcccgtttca gcatccggct gaaatctgcg gcttacctcc tttcgccctg tatgcagtct
     2761 atcgctgacg cgtagataaa atagtttcct gtgttattac tggatgcgtg ctcgcaaatg
     2821 tgcccgccat tcagacgatt cccgatagtg tttcataatt cctccatttt tctcccttat
     2881 tggctggcta cactagtatc attccgcgaa acgtttcagg aagagaaact cttaacgatg
     2941 aaaggcagtt ataaatcccg ttgggtaatc gtaatcgtgg tggttatcgc cgccatcgcc
     3001 gcattctggt tctggcaagg ccgcaatgac tcccagagtg cagccccagg ggcgacgaaa
     3061 caagcgcagc aatcgccagc gggtggtcgc cgtggtatgc gttccggccc attagccccg
     3121 gttcaggcgg cgaccgccgt agaacaggca gttccgcgtt acctcaccgg gcttggcacc
     3181 attaccgccg ctaatactgt tacggtgcgc agccgcgtgg acggtcaact gatggcgtta
     3241 catttccagg aaggccagca ggtcaaagca ggcgatttac tggcagaaat tgaccccagc
     3301 cagttcaaag ttgcattagc acaagcccag ggccaactgg caaaagataa agccacgctt
     3361 gctaacgccc gccgtgatct ggcgcgttat cagcaactgg caaaaaccaa tctcgtctcc
     3421 cgtcaggagc tggatgccca acaggcgctg gtcagtgaaa ccgaaggcac cattaaggct
     3481 gatgaagcaa gcgtcgccag cgcgcagctg caactcgact ggagccgcat caccgcacca
     3541 gtcgatggtc gcgttggtct caagcaggtt gatgttggta accaaatctc cagtggtgat
     3601 accaccggaa ttgtggtgat cacccagacg catcctatcg atttagtctt taccctgccg
     3661 gaaagcgata tcgctactgt agtgcaggcg caaaaagccg gaaaaccgct ggtggtagaa
     3721 gcctgggatc gtaccaattc gaagaaatta agtgaaggca cgctgttaag cctcgataac
     3781 caaatcgatg ccacaaccgg tacgattaaa gtgaaagcac gctttaataa tcaggatgat
     3841 gcgctgtttc ccaatcagtt tgttaacgcg cgcatgttag tcgacaccga acaaaacgcc
     3901 gtagtgatcc caacagccgc cctgcaaatg ggcaatgaag gccattttgt ctgggtgctg
     3961 aatagcgaaa acaaggtcag caaacatctg gtgacgccgg gcattcagga cagtcagaaa
     4021 gtggtgatcc gtgcaggtat ttctgcgggc gatcgcgtgg tgacagacgg cattgatcgc
     4081 ctgaccgaag gggcgaaagt ggaagtggtg gaagcccaga gcgccaccac tccggaagag
     4141 aaagccacca gccgcgaata cgcgaaaaaa ggagcacgct cctgatgcag gtgttacccc
     4201 cgagcagcac aggcggcccg tcgcgccttt ttattatgcg tcctgtcgcc accacgctgc
     4261 tgatggtggc gatcttactc gccgggatta tcggttatcg cgccctgccc gtttcggcgc
     4321 tgccggaagt ggactatccg accattcagg tggtcacgct ctacccaggt gccagcccgg
     4381 atgtcatgac ctctgccgtt accgcgccgc tagaacgcca gttcgggcag atgtctggcc
     4441 tgaaacagat gtcgtcgcaa agttccggcg gtgcgtcagt tatcactttg cagttccagc
     4501 taacattacc gctcgatgtc gccgagcagg aagtgcaggc cgcgattaac gctgcgacca
     4561 acttgttgcc gagcgatctg cctaacccgc cggtttacag caaagtgaac ccggcagatc
     4621 cgccgatcat gacgctcgcc gtcacctcaa ccgccatgcc gatgacgcaa gtggaagata
     4681 tggtggaaac ccgcgtcgcg cagaaaatct cgcagatttc cggtgtcgga ctggtgacgc
     4741 tttccggcgg tcagcgtccg gctgttcgcg tcaaacttaa cgctcaggcg attgccgccc
     4801 tcggcctgac cagcgaaacc gtgcgcaccg ccattaccgg cgctaacgtt aactcggcaa
     4861 aaggtagcct cgacggccct tcccgtgcgg ttacgctttc cgctaacgac cagatgcaat
     4921 ccgccgaaga gtatcgccag ctaatcatcg cctaccagaa cggcgcgcca attcgtctgg
     4981 gcgatgtcgc aactgtagag caaggtgcag aaaacagctg gctcggcgcg tgggcgaaca
     5041 aagaacaggc cattgtgatg aatgttcagc gccagcccgg tgctaacatt atctccaccg
     5101 ccgacagcat tcggcagatg ctgccacagc tcactgagag tctgccgaaa tcggtgaagg
     5161 tgacagtgct ttccgatcgc accaccaata tccgcgcatc cgtcgatgat actcagtttg
     5221 aattgatgat ggctatcgcg ctggtagtca tgattatcta cctgtttttg cgcaatattc
     5281 cggcgaccat cattcccggt gttgctgtac cgctgtcgtt aatcggcact ttcgcggtta
     5341 tggtgtttct cgatttttca atcaataacc tgacactgat ggcgttaact atcgccaccg
     5401 gattcgtggt cgatgacgcc atcgtggtga tcgaaaacat ttcccgctat atcgaaaaag
     5461 gcgaaaaacc gttggcggcg gcgctcaagg gcgcaggtga aatcggcttt accattatct
     5521 cgctgacctt ctcactgatt gcggtgttga tcccactgct gtttatgggc gatatcgtcg
     5581 ggcgactgtt ccgcgaattt gctattaccc tggcggtagc gattttgatc tcagcggtgg
     5641 tgtcgctgac cctgacaccg atgatgtgcg cgcggatgct cagccaggag tcgttgcgta
     5701 aacagaaccg cttctcccgt gcctcggaaa aaatgttcga caggataatc gccgcctatg
     5761 gtcgtggact ggcgaaagtg ctgaatcatc cgtggctgac cttaagcgtg gcactcagca
     5821 cgctgctgct tagcgtgctg ctgtgggtgt tcattccgaa aggtttcttc ccggtacagg
     5881 acaatggcat tattcagggc actttgcagg caccgcaatc cagctccttt gccaatatgg
     5941 cccagcgaca acgccaggtc gcggacgtga ttttgcagga tccggcagtg caaagcctga
     6001 cctcatttgt tggcgttgat ggcactaacc cgtcgctgaa cagtgcacgt ttacaaatca
     6061 acctcaaacc gttggatgaa cgtgatgatc gggtgcaaaa agtcatcgcc cgtctgcaaa
     6121 cggcggtaga taaagtgccg ggcgtcgatc tcttcctgca accaacgcag gatctgacta
     6181 ttgatactca ggtcagccgc acccagtacc agtttacctt gcaggccacg tcactggatg
     6241 cgctcagtac ctgggtgcca cagttgatgg aaaaactcca gcaactgcca cagctttctg
     6301 atgtctccag cgactggcag gacaaagggc tggtggcgta tgtcaatgtt gatcgcgaca
     6361 gcgccagccg cctggggatc agcatggcgg atgtcgataa cgccctgtac aacgcgtttg
     6421 gtcagcggct gatttccact atttatactc aggccaacca gtatcgcgtg gtgctggagc
     6481 acaacaccga aaatacccca ggcctcgcgg cgctggatac cattcgcctg accagcagcg
     6541 acggcggcgt ggtgccgcta agctcaattg ccaaaattga gcagcgtttt gcgccgctct
     6601 ccatcaacca tctggatcag ttcccggtaa cgaccatctc ctttaacgtg ccggataact
     6661 attcgctggg cgatgcggtg caggcgatta tggacaccga aaagacgctg aatctgccgg
     6721 tggatatcac cacgcagttc cagggcagca ccctcgcctt ccagtcggcg ctgggcagca
     6781 ctgtctggct gattgtcgcg gcggtggtgg cgatgtatat cgtgctcggc attctgtacg
     6841 agagctttat tcacccgatc accattctct cgacgctacc caccgcaggg gttggcgcac
     6901 tgctggcgtt gctgattgct ggtagcgaac tggatgtgat tgcgattatc ggcattattt
     6961 tgctgatcgg tatcgtgaag aagaacgcca tcatgatgat cgacttcgcg ctggctgccg
     7021 agcgcgagca aggcatgtcg ccgcgcgagg caatctacca ggcttgtctg ttgcgttttc
     7081 gtccgatcct gatgaccact ctggcggctc tgcttggcgc gctgccgctg atgttgagta
     7141 ccggggtcgg cgcggaactg cgtcgtccgt taggtatcgg catggtcggc ggtctgattg
     7201 tcagccaggt gctgacgctg tttaccacgc cggtgattta tttgctgttc gaccgcctgg
     7261 cattgtggac caaaagccgc tttgcccgtc atgaagagga ggcgtaagtg aagttttttg
     7321 ccctcttcat ttaccgcccg gtggcgacga ttttactgtc ggttgccatt accctgtgcg
     7381 gcatactggg cttccgtatg ctgccggtcg ccccgctgcc gcaggtcgat tttccggtga
     7441 ttatggtcag cgcctcgctg cccggtgcgt caccagaaac aatggcgtct tccgttgcca
     7501 cgccgctgga gcgctcactt gggcgcattg ccggagtcag tgaaatgacc tccagcagtt
     7561 cgctcggcag cacgcgtatt attttgcagt ttgattttga ccgggatatc aacggcgcgg
     7621 cgcgcgatgt gcaggcggcg atcaacgctg cacaaagttt gctgcccagc gggatgccca
     7681 gccgtccgac ctatcgcaaa gctaacccgt cggatgcgcc aattatgatc ctcacgctga
     7741 catccgatac ttattcgcag ggtgaactgt acgattttgc ctcgacgcag ctggctccga
     7801 cgatttcgca aatcgacggt gttggtgatg tcgatgtcgg cggcagctca ctgcccgccg
     7861 tacgcgtcgg gctgaatccg caggcgctgt ttaatcaggg cgtctcgctg gacgacgtac
     7921 gcactgccat cagcaatgcc aacgtgcgta aaccgcaggg ggcgctggaa gatggcactc
     7981 accgctggca gatccagacc aatgatgagc taaaaaccgc cgccgaatat cagccgctga
     8041 ttattcatta caacaacggc ggcgcggttc gtctgggcga tgtggcgaca gtgaccgact
     8101 ctgtacagga tgtacgtaac gccgggatga ccaatgccaa accggctatt ttgctgatga
     8161 tccgcaagct gccggaagcc aatattatcc agacggttga cagcatccgg gcaaaattac
     8221 cggagttgca ggaaaccatt ccggcggcga ttgatctgca aattgcccag gatcgctccc
     8281 ccaccattcg ctcctcgctg gaagaagtcg agcaaacgct gattatctcg gtggcgctgg
     8341 tgattctggt ggtgttttta ttcctgcgct cgggtcgcgc cactattatt cccgccgttt
     8401 cggtgccggt ttcgctgatt ggtacgtttg cggcgatgta cctgtgcgga ttcagtctca
     8461 ataacctttc gttaatggcg ctcaccatcg ctactggttt cgtggtggat gacgccatcg
     8521 tggtgctgga aaacattgcc cgtcatctgg aagcgggaat gaaaccgttg caagccgcac
     8581 tgcaaggtac tcgcgaagtc ggttttacgg tgctgtcgat gagtctgtca ctggtggcgg
     8641 tgttcctgcc gctgctgttg atgggcggat tgccgggccg actgttacgc gagtttgccg
     8701 tgacgctttc tgtcgccatt ggtatttcgt tgctggtttc tctgacatta acgccaatga
     8761 tgtgtggctg gatgctgaaa gccagcaagc cgcgcgagca aaagcgactg cgtggttttg
     8821 gtcgcatgtt ggtagccctg caacaaggct acggcaagtc actgaactgg gtgctcaatc
     8881 atacccgtct ggtgggcgtg gtgctgcttg gcaccattgc gctgaatatc tggctgtata
     8941 tctcgatccc gaaaaccttc ttcccggagc aggacactgg cgtgctgatg ggcgggattc
     9001 aggcggatca gagtatttcg tttcaggcga tgcgcggtaa gttgcaggat ttcatgaaaa
     9061 ttatccgtga cgatccggca gtggataatg tcaccggctt tacaggcggt tcgcgagtga
     9121 acagcgggat gatgtttatc accctcaagc cacgcgacga acgcagcgaa acggcgcagc
     9181 aaattatcga ccgtctgcgc gtaaaactgg cgaaagaacc gggggcgaat ctgttcctga
     9241 tggcggtaca ggatattcgc gttggtgggc gtcagtcgaa cgccagctac cagtacacgt
     9301 tgttatccga cgacctggcg gcactgcgcg aatgggagcc gaaaatccgc aaaaaactgg
     9361 cgacgttgcc ggaactggcg gacgtgaact ccgatcagca ggataacggc gcggagatga
     9421 atctggttta cgaccgcgac accatggcac ggctgggaat cgacgtacaa gccgccaaca
     9481 gtctgttaaa taacgccttc ggtcagcggc aaatctcgac catttaccag ccgatgaacc
     9541 agtataaagt ggtgatggaa gtggatccgc gctataccca ggacatcagt gcgctggaaa
     9601 aaatgttcgt tatcaataac gaaggcaaag cgatcccgct gtcgtatttc gctaaatggc
     9661 aaccggcgaa tgccccacta tcggtgaatc atcagggatt atcggcggcc tcgaccattt
     9721 cgttcaacct gccgaccgga aaatcgctct cggacgccag tgcggcgatc gatcgcgcaa
     9781 tgacccagct tggtgtgcct tcgacggtgc gcggcagttt tgccggaaca gcgcaggtgt
     9841 tccaggagac gatgaactca caggtgatcc tgattatcgc cgccatcgcc acggtgtata
     9901 tcgtgctggg tatcctttac gagagttatg tgcacccgct gacgattctc tccaccctgc
     9961 cctcggcggg tgttggagcg ctgctggcgc tggagctgtt caatgccccg ttcagcctaa
    10021 tcgccctgat agggatcatg ctattaatcg gcatcgtgaa gaaaaacgcc attatgatgg
    10081 tcgattttgc gcttgaagcc caacggcacg gtaacctgac gccgcaggaa gctattttcc
    10141 aggcctgtct gctgcgtttt cgcccgatta tgatgactac cctggcggcg ctgtttggcg
    10201 cgctgccgct ggtgttgtcg ggcggcgacg gctcggagct gcggcaaccc ctggggatca
    10261 ccattgtcgg cggactggta atgagccagc tccttacgct gtataccacg ccggtggtgt
    10321 atctcttttt cgaccgtctg cggctgcgtt tttcgcgtaa acctaaacaa acggtaaccg
    10381 agtaaatgac agatcttccc gacagcaccc gttggcaatt gtggattgtg gctttcggct
    10441 tctttatgca gtcgctggac accaccatcg taaacaccgc ccttccctca atggcgcaaa
    10501 gcctcgggga aagtccgttg catatgcaca tggtcattgt ctcttatgtg ctgaccgtgg
    10561 cggtgatgct gcccgccagc ggctggctgg cggacaaagt cggcgtgcgc aatattttct
    10621 ttaccgccat cgtgctgttt actctcggtt cactgttttg cgcgctttcc ggcacgctga
    10681 acgaactgtt gctggcacgc gcgttacagg gcgttggcgg cgcgatgatg gtgccggtcg
    10741 gcagattgac ggtgatgaaa atcgtaccgc gcgagcaata tatggcggcg atgacctttg
    10801 tcacgttacc cggtcaggtc ggtccgctgc tcggtccggc gctcggcggt ctgctggtgg
    10861 agtacgcgtc gtggcactgg atctttttga tcaacattcc ggtggggatt atcggtgcga
    10921 tcgccacatt gatgttaatg ccgaactaca ccatgcagac gcggcgcttt gatctttccg
    10981 gctttttatt gctggcggtt ggcatggcgg tattaaccct ggcgctggac ggcagtaaag
    11041 gtacaggttt atcgccgctg gcgattactg gcctggtcgc agttggcgtg gtggcactgg
    11101 tgctttatct gctgcacgcc agaaataaca accgcgccct gttcagtctg aaactgttcc
    11161 gcactcgtac cttttcgctg ggcctggcgg ggagctttgc cggacgtatt ggcagtggca
    11221 tgttgccctt tatgacaccg gttttcctgc aaattggcct cggtttctcg ccgtttcatg
    11281 ccggactgat gatgatcccg atggtgcttg gcagcatggg aatgaagcga attgtggttc
    11341 aggtggtgaa tcgctttggt tatcgtcggg tactggtagc gaccacgctg ggtctgtcgc
    11401 tggtcaccct gttgtttatg actaccgctc tgttgggctg gtactacgtt ttgccgttcg
    11461 tcctgttttt acaaggaatg gtcaactcaa cgcgtttctc ctccatgaac accctgacgc
    11521 tgaaagatct cccggacaat ctggcgagca gcggaaacag cctgctgtcg atgattatgc
    11581 aattgtcgat gagtatcggc gtcactatcg ccgggctgtt gctgggactt tttggttcac
    11641 agcatgtcag cgtcgacagc ggcaccacac aaaccgtctt tatgtacacc tggcttagca
    11701 tggcgttgat catcgccctt ccggcgttca tctttgccag agtgccgaac gatacgcatc
    11761 aaaatgtagc tatttcgcgg cgaaaaagga gcgcgcaatg aagttctggc gacccggtat
    11821 taccggcaaa ctgtttctgg cgattttcgc cacctgcatt gtcttgctga tcagtatgca
    11881 ctgggcggtg cgtatcagtt ttgagcgtgg ctttattgat tacatcaagc atggtaatga
    11941 acaacgatta caactgttaa gtgatgcgct tggcgagcag tatgcgcagc atggcaactg
    12001 gcgcttccta cgcaacaatg atcgctttgt ctttcagatc ctgcgttcat ttgaacacga
    12061 taattcggaa gataaacccg gcccgggtat gccaccgcac ggctggcgta cccagttctg
    12121 ggtggttgat caaaacaaca aagtgctggt tggtccgcga gcgccgattc cacctgacgg
    12181 tacacggcga cccattctgg tcaacggtgc ggaagttggc gcggtgatcg cctcccccgt
    12241 tgagcggtta acgcgcaata ctgatatcaa tttcgataaa caacagcggc aaaccagctg
    12301 gctgatcgtc gccctggcaa cgttactcgc ggcgctcgcc acctttctgc tggcgcgcgg
    12361 tttgctggca ccggtaaaac gacttgtcga tggcacgcac aaactggcgg cgggcgattt
    12421 cactacccgc gtaacgccca ccagtgaaga tgaactgggc aaactggcgc aagacttcaa
    12481 ccagcttgcc agcacgctgg agaaaaacca gcaaatgcgg cgcgatttta tggccgatat
    12541 ttcacacgaa ctgcgtacgc cattagcggt gctgcgcggt gaactggaag ccattcaaga
    12601 tggcgtgcgc aaattcacgc cggagacggt ggcgtcttta caggcggaag tcggtacact
    12661 gactaaactg gttgacgatc ttcatcagtt gtcgatgtct gatgaaggcg ctctcgccta
    12721 tcaaaaagca ccggtagatt tgatcccact gctggaagtg gcgggcggcg catttcgcga
    12781 acgatttgcc agccgtggcc tgaaactgca gttttccctg ccagacagta ttaccgtatt
    12841 tggcgatcgc gaccgtttaa tgcagttatt caataactta ctcgaaaaca gcctgcgcta
    12901 cactgatagc ggcggcagcc tgaaaatctc tgccgagcag cacgacaaaa cggtgcgcct
    12961 gacctttgcc gacagtgcgc caggtgtcag tgacgagcag ctacaaaaat tatttgaacg
    13021 tttttatcgc accgaaggtt cccgcaaccg cgccagcggt ggttccgggc tggggctggc
    13081 gatttgcctg aacattgttg aagcacataa tggccgcatt attgctgccc attcgccttt
    13141 tggcggggta agcattacag tagagttacc gctggaacgg gatttacaga gagaagtatg
    13201 accgagttac caatcgacga aaacacaccg cgtattttga tcgtggaaga tgaaccgaag
    13261 ctggggcagt tgctcattga ttatctgcgt gctgcgagct atgcgccgac gcttatcagc
    13321 cacggcgatc aggtactgcc gtatgtgcgc cagacaccac cggatctgat cctgttagat
    13381 ctgatgctcc ctggcaccga tggcctgacg ctgtgccggg aaattcgtcg tttttctgac
    13441 attccgatcg tgatggtgac ggcaaaaatc gaagagatcg atcgcctgct ggggctggag
    13501 attggcgcag atgattatat ctgtaagccg tacagcccac gggaagtggt agcgcgcgtc
    13561 aaaaccattt tgcgccgttg caaaccgcag cgcgagttgc agcaacagga tgctgaaagc
    13621 ccgttgatta tcgacgaagg tcgttttcag gcttcatggc gcggtaaaat gcttgacctg
    13681 acgcctgcgg aatttcgtct gctgaaaacg ctctctcatg aaccaggaaa agtgttctcc
    13741 cgcgagcatt tgctcaatca tctttatgac gactaccgcg tagtaaccga ccgcaccatc
    13801 gacagccaca ttaaaaacct gcgccgcaag ctggaatctc tcgacgccga acagtcattt
    13861 atccgcgccg tttacggcgt tggttaccgc tgggaagccg acgcctgccg catcgtttag
    13921 ttttagcgac atgactttgt tagccggaga tggcgttcag accagatccg gcaacattat
    13981 cccacgcatg gtcagcaaac tgacattatc tctccgccct ggcaggcatc agaaaatcgc
    14041 tcatacttta atcggtaaac agcaccttta gatgctgttt tcgatacgca atttcaatca
    14101 aggagtcatt atggctggtt ggtttgaact cagtaagagc agtgataatc agttccggtt
    14161 tgtgctaaaa gcgggcaatg gtgagactat cctcaccagc gagctgtata cctcaaaagc
    14221 ctctgcggaa aagggcatcg cgtcggtgcg tagcaacagc ccgcaagaag aacgctatga
    14281 gaaaaaaacg gcaagtaacg gcaaattcta tttcaatctg aaagccgcta atcatcaaat
    14341 tatcggctcc agccagatgt acgccaccgc gcaatctcgt gaaaccggaa ttgcctccgt
    14401 taaagccaat ggcacaagcc agacggtgaa agacaatacg taattacgat gccgggcgtg
    14461 ggttgttggc gtccggcttt atatccaaat aacgcttagt tattaataat taagagtaac
    14521 cgccgccatt aaaatagtgg gcactgacga gcactcgttg tgctttcttt gtttaccatc
    14581 ccatacttat cctcctgaac atgttcatgt gccaaaatat cttctaatac tttcgtgacg
    14641 ctatccggtt tatgacatac actgatgtaa gatttttact tacaggcggg cgtaaaatgg
    14701 ccagaacgat gacggttgat ctcggcgatg agttgcgtga atttatcgag tccttaattg
    14761 aatccggcga ctatcgcacc caaagcgaag tgatccgtga gtcactgcga ttacttcgag
    14821 aaaagcaagc agagtctcgc ctgcaagcgt tacgtgacat gctcgcagaa gggttgagta
    14881 gtggtgaagc tcagccgtgg gaaaaggacg cgttcttacg gaaggtgaaa gcagggataa
    14941 ggaaataatg tgcgtattat taaactcatg ccaaaagcca atgaggattt agaaggcatc
    15001 tggtattaca gctatcacca tttcggcgaa ccacaagccg acagatatgt ggaacatctt
    15061 tcagacgttc tccagattct gagtaacaat aatataggta cgcccagacc tgaattaggc
    15121 gaaggtattt ttgttcttcc ttttgaacgc cacgtcattt atttcctgca atcaccaggg
    15181 gaaattatcg tcattcgtat ccttaaccaa aaccaggacg ccaccagaca tttacactgg
    15241 agctaaaccc gccgattgcg ctacaatgcc cgcccttaaa gtgggggcac tcccctaacc
    15301 gcttcatcag gtgaagcgga tctgacctgt catcagaacg agagaattat gtttaaaccg
    15361 gaactccttt ccccggcggg aacgctgaaa aatatgcgtt acgctttcgc ttatggcgca
    15421 gatgctgttt atgcgggcca gccgcgttat tccctgcgtg tgcgcaacaa cgaattcaac
    15481 cacgaaaatc ttcagctcgg catcaatgaa gcccacgcgc tggggaaaaa gttttatgtc
    15541 gtggtcaaca ttgcaccgca caacgccaag ctgaaaacct ttatccgtga cctgaaaccg
    15601 gtggtggaaa tggggccgga tgcgctgatt atgtccgatc cagggctgat tatgctggtg
    15661 cgtgagcact tccctgaaat gccgatccac ctttcggtgc aggctaacgc cgtgaactgg
    15721 gcgacggtga aattctggca gcaaatgggc ctgacccgcg tgatcctctc tcgcgagctg
    15781 tcgctggaag agattgaaga gatccgcaat caggtgccgg atatggagat cgagatcttc
    15841 gttcacggcg cgctgtgcat ggcctactcc ggtcgctgcc tgctctctgg ctatatcaac
    15901 aagcgcgacc cgaaccaggg cacctgcacc aacgcctgcc gctgggagta caacgtccag
    15961 gaagggaaag aagatgatgt tggcaacatc gtacacaagt acgagccgat tccggtgcaa
    16021 aatgttgagc cgacgctggg tatcggcgca ccaaccgaca aagtgtttat gatcgaagag
    16081 gcccagcgtc cgggcgagta tatgaccgcg tttgaagatg agcacggcac ttacatcatg
    16141 aactcgaaag atctgcgcgc catcgcccat gtagaacgcc tgaccaaaat gggcgtgcat
    16201 tcgctgaaaa tcgaaggccg tactaaatct ttctactatt gcgcacgcac cgcacaggtt
    16261 taccgtaaag ctatcgatga cgccgctgcg ggcaaaccgt tcgataccag cctgctggaa
    16321 actctggaag gtctggcgca tcgtggctat accgaaggtt tcctgcgtcg tcatactcac
    16381 gacgattatc agaactacga atacggttat tcagtttctg accgccagca gtttgttggt
    16441 gagtttaccg gtgagcgcaa gggggacctc gcggcggtag cggtgaaaaa taaattctcc
    16501 gttggcgaca gccttgagct gatgacgccg caaggcaaca ttaactttac ccttgagcac
    16561 atggaaaacg ccaaaggtga agcgatgccg gtcgcaccag gcgatggtta tactgtgtgg
    16621 ctcccggtcc cgcaggatct tgagctcaat tacgctctgc tgatgcgtaa tttctccggg
    16681 gaaaccacgc gtaacccaca cggtaagtga ttaatttcga ttatttttcc cggatggaaa
    16741 attcttagaa accgatcaca tacagctgca tttattaagg ttatcatccg tttcgctgaa
    16801 aaacataacc cataaaatgc tagctgtacc aggaaccacc tccttagcct gtgtaatctc
    16861 ccttacacgg gcttattttt ttatgcataa gccctatctc tggtaaccgt cttccattga
    16921 ccacatcgat agaatcctcc ttcatagcac gatgcctttc acttatcggc atcgtgctcc
    16981 cacaggttcc ggctacgcac agccagaacg cgcatatttg acgcttacca aaaaatattc
    17041 tcactctcca catttgaatg tcagacgagc gacaccatgt aatcctacac cttctgtctt
    17101 cagctcaact atttgcattt ttttgccctg agtaacacag aaatgagttg catcattttt
    17161 tactatattt tctgcaccag atattctacc cctggctaaa gaagcttcgg cttcggtgta
    17221 gtattggtta tcgagtttac gctgaatatt acttttatat gcaagaccaa atttaccgat
    17281 acttgtct
//
LOCUS       DAPHKZ010000096        16933 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.096, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000096 DAPHKZ010000000
VERSION     DAPHKZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16933
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.096"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(377..1573)
                     /gene="hemY"
                     /locus_tag="RH288_003302"
     CDS             complement(377..1573)
                     /gene="hemY"
                     /locus_tag="RH288_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HDV4032333.1"
                     /translation="MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKVHV
                     GDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTL
                     GQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRHDGLMLTL
                     QNNPPQ"
     gene            complement(1576..2763)
                     /gene="hemX"
                     /locus_tag="RH288_003303"
     CDS             complement(1576..2763)
                     /gene="hemX"
                     /locus_tag="RH288_003303"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDV4032334.1"
                     /translation="MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAI
                     ALAAGVGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAAQLKQA
                     NRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAALL
                     KSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYDGIILKLNQLSNQVDNLRLAD
                     NDSDGSPMDSDGEELSSSISEWRINLQKSWQNFMDNFITIRRRDDTAVPLLAPNQDIY
                     LRENIRSRLLVAAQAVPRHQEETYRQALENVSTWVRAYYDTDDATTKAFLDEVDQLSQ
                     QNISMDLPETLQSQAMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPAPAPQGDTPAAAP
                     QGE"
     gene            complement(2785..3525)
                     /gene="hemD"
                     /locus_tag="RH288_003304"
     CDS             complement(2785..3525)
                     /gene="hemD"
                     /locus_tag="RH288_003304"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HDV4032335.1"
                     /translation="MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGQQLPQLA
                     DQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPRLPDYFAIGRTTALALHTVSGQK
                     ILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGAEVTFCECYQR
                     CAIHYDGAEEAMRWQSREVTTVVVTSGEMLQQLWSLIPQWYREHWLLHCRLLVVSERL
                     AKLARELGWQDIKVADNADNDALLRALQ"
     gene            complement(3522..4463)
                     /gene="hemC"
                     /locus_tag="RH288_003305"
     CDS             complement(3522..4463)
                     /gene="hemC"
                     /locus_tag="RH288_003305"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDV4032336.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICERE
                     DPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
                     NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAA
                     LNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGER
                     RGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA"
     gene            4850..7396
                     /gene="cyaA"
                     /locus_tag="RH288_003306"
     CDS             4850..7396
                     /gene="cyaA"
                     /locus_tag="RH288_003306"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HDV4032337.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC
                     EKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLY
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEG
                     IIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS"
     gene            complement(7436..7756)
                     /gene="cyaY"
                     /locus_tag="RH288_003307"
     CDS             complement(7436..7756)
                     /gene="cyaY"
                     /locus_tag="RH288_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HDV4032338.1"
                     /translation="MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGET
                     VSFR"
     gene            8219..8422
                     /locus_tag="RH288_003308"
     CDS             8219..8422
                     /locus_tag="RH288_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV4032339.1"
                     /translation="MKNVFKALTVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKPVET
                     QTQSTVPDKNDRATGDGPSQVNY"
     gene            8459..9283
                     /gene="dapF"
                     /locus_tag="RH288_003309"
     CDS             8459..9283
                     /gene="dapF"
                     /locus_tag="RH288_003309"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDV4032340.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL"
     gene            9280..9987
                     /locus_tag="RH288_003310"
     CDS             9280..9987
                     /locus_tag="RH288_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HDV4032341.1"
                     /translation="MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVP
                     HPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSL
                     DDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLH
                     EIALMLPELLERWIERV"
     gene            9984..10880
                     /gene="xerC"
                     /locus_tag="RH288_003311"
     CDS             9984..10880
                     /gene="xerC"
                     /locus_tag="RH288_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDV4032342.1"
                     /translation="MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENG
                     LQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVS
                     APKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
                     DLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISAR
                     NVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYT
                     HLDFQHLASVYDAAHPRAKRGK"
     gene            10880..11596
                     /gene="yigB"
                     /locus_tag="RH288_003312"
     CDS             10880..11596
                     /gene="yigB"
                     /locus_tag="RH288_003312"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HDV4032343.1"
                     /translation="MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHP
                     ALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAM
                     INFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
                     RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTW
                     DSRLLPHLEISRLASLTSLI"
     gene            11680..13842
                     /gene="uvrD"
                     /locus_tag="RH288_003313"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             11680..13842
                     /gene="uvrD"
                     /locus_tag="RH288_003313"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HDV4032344.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIA
                     WLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAET
                     IRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFG
                     EGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLESV"
     gene            complement(13989..14753)
                     /locus_tag="RH288_003314"
     CDS             complement(13989..14753)
                     /locus_tag="RH288_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HDV4032345.1"
                     /translation="MAHQLLIGKGMITLNLKRIFLALTLLPLFAVAADDCALSDPTLT
                     VQAYTVNPQTERVKMYWQKANGEAWGTLHALLADINSQGQVQMAMNGGIYDESYAPLG
                     LYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
                     MLMENGVINPRIHPNVASSKIRNGVGINKHGNAVFLLSQQATNFYDFACYAKAKLNVE
                     QLLYLDGTISHMYMKGGAIPWQRYPFVTMISVERKG"
     gene            15123..16073
                     /gene="corA"
                     /locus_tag="RH288_003315"
     CDS             15123..16073
                     /gene="corA"
                     /locus_tag="RH288_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HDV4032346.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL"
     gene            complement(16116..16496)
                     /locus_tag="RH288_003316"
     CDS             complement(16116..16496)
                     /locus_tag="RH288_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HDV4032347.1"
                     /translation="MSKEYMNDGSLSEKWKYRFNFYDQHSFPGFWGATPEYKAAFKAL
                     KVRQRLTIQMNFIAFFCSWIYLFVLGLWKKAIIVLLLGILSLFVGALIGVNILGIAVA
                     AYVAVNTNKWFYEKEVKGLNTWSL"
     gene            complement(16510..16926)
                     /locus_tag="RH288_003317"
     CDS             complement(16510..16926)
                     /locus_tag="RH288_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709624.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032348.1"
                     /translation="MLTGDSYKDVKFMLRIFIPTSNGKISRRRYIFSFILINFIFAFL
                     IIFFNDGEAGFLVIVSTIVLHYLVINMNCQRLRDSGFIYIKTYVFGTLAVYIISIITM
                     IAEDFACSGNGSMIFLICYFSTFSMLMLAPTDSSKQ"
BASE COUNT         3944 a         4369 c         4496 g         4124 t
ORIGIN      
        1 caagctcagg ttaaatattc actcaggaag ttattactca ggaagcaaag aggattacag
       61 aattatctca taacaagtgt taagggatgt tatttcccga ttctctgtgg cataataaac
      121 gagtagatgc tcattccatc tcttatgttc gccttagtgc ctcataaact ccggaatgac
      181 gcagagccgt ttacggtgct tatcgtccac tgacagatgt cgcttatgcc tcatcagaca
      241 ccatggacac aacgttgagt gaagcaccca cttgttgtca tacagacctg ttttaacgcc
      301 tgctccgtaa taagagcagg cgttttttta tgtgtcagga aggccccgga ggtgcttgcc
      361 cccgggtgag aaggaactac tgtggtgggt tgttctgcaa cgttaacatc aaaccgtcgt
      421 gacgcatcgc tgcagcttct tccggcttgt gcagtctgtc cagcgcgtcg gcaagccatg
      481 cgtaatcgta ggcgtccgga cgttgtttca gcgctgcgcg gaaggcgagc gatgcttcct
      541 gccattctcc gtgcttcatc agtgactggc ccagtgtgct ccacaacagc gggcgatcgc
      601 cgacgttttt gatctgctgg cgcagcactt tttccagctg ttccggattg ttggttttca
      661 gtcgaggaat cggcagcagt aggcgatcgt cgtactggcg tttcaggcca tcgatgataa
      721 tttgctgggc agtatcatga tcgtcacatt caataagatg ttccgccatt gccacctgca
      781 acgctacctg atgacgcgtt ttccggcttt ggtttttcca ccagttacgc aaaccttcac
      841 taccgttatc ggcacgcgcc tgatccatca ggccaatcca tgcctgttgt tccagcattg
      901 cacgatgttc ttcatcacca acatggactt tcgccattga tgggatgata tccagcagag
      961 aactccatgc acctgtgcgg atatacgcct gttccgccag acgtaatact tccggatggc
     1021 gtggcgtaac ttccagcagc ttatccacgc cgtggcgtgc agcatggttt tcattacggg
     1081 ccagttgcag acgtacacgg gtgatttcta ccggaatggt gtcattgccg gccagctccg
     1141 ctgcgcgttc cagatgttgg ttggcgcgcg cttcatcacc acgttgttgc gcggcttcgg
     1201 cagccagtag atagttcacc accggttgtt cagcgtgatc ggcatttttc gccatcagct
     1261 tttcaacttg ctgataatcg ccttccgcca gtttcagcag cgcctgttcg gtctgcttac
     1321 gtgcacggcg acgcttacgc ccgacaaacc acccacgggt gtgcgcgcca gtgcggaaga
     1381 tccgccgcag tagccactca atggcaaaca gcactaccat cgccagaatc aatatgatcg
     1441 ccaggcccgt gacgctggtt tcgatattgt agttgtcggt ctggatcagc acataaccct
     1501 gatgaccggc aatcatcggg ccaaccacta tccccgcaat cagcaacaca aagagtaata
     1561 acacttttag catggttatt ctccttgcgg cgcggctgcc ggagtatcac cttgcggtgc
     1621 aggtgcaggt gcaggtgcag gtttagcttc cgttgtccct gctgccggtt gtgccagcag
     1681 gttacgcacg cgagtctgca tcagtttttc cagcatcgcc tggctttgca gggtttccgg
     1741 aagatccatc gagatatttt gctggcttaa ctggtccacc tcgtcgagga acgctttggt
     1801 ggtggcatca tcagtatcgt agtaagcacg tacccaggtg gagacgttct ccagcgcctg
     1861 gcgataagtc tcttcctggt gacgcggtac agcttgtgct gcgaccagca ggcgagagcg
     1921 aatattttcg cgcagataga tatcctgatt tggcgctaac agcggtacgg cggtgtcatc
     1981 acgacggcga atcgtaatga agttgtccat aaagttctgc cagctttttt gcagattgat
     2041 acgccattcg ctgatggaac tggaaagctc ttcaccgtct gaatccatcg gcgaaccatc
     2101 gctgtcatta tcggccagac gcaggttatc tacctgattt gaaagctgat taagcttaag
     2161 gatgatgccg tcataatcca cctgcgatac tgcagaaagg ctggcgatat catcggtaat
     2221 tgcccgacga acggtaatca gactcgggtc attcatatcc gccaggctgg cgtctgcact
     2281 tttcagcaac gctgcagcgg tcgtgacgtc ctgatcgctc cacagcttcc gtccggcgag
     2341 tttcaccaga aaatcggcct gagccagcag ccaggtttta gcatcgctgc cggaaatggt
     2401 ggcgaccttt tgttggacct catccaactg ttttgccagc gtttcttgct gacgattcgc
     2461 ctgcttaagc tgtgcagctt gttgcttaat aatgccttcc agctcggctt tttggctctc
     2521 ctgggctttt tgcaatgccg tcagttggtt agccagggca tcgctggtgg cggtctgatt
     2581 gacggcctgt tgtttacccc agccatacaa accgacgccc gccgccagag caatagccac
     2641 cgcgctgaga atcaatgcgg tattgttctt actctttttt tctgttgcga caggttgtga
     2701 cgtggtgtcc acggcctccc tggtctcttc aaccacggcg gaggtttttt cttgttccgt
     2761 cattatggct tcctgttatg agagttattg taatgcccgt aaaagcgcat cgttgtcagc
     2821 gttatcggcg accttaatgt cttgccagcc cagttcccgg gcgagtttcg ccaaacgctc
     2881 actgacgacc aatagtcgac agtgtagtaa ccagtgctca cgataccatt gtgggatcag
     2941 cgaccagagt tgctgcaaca tttcaccgct ggtaacaacg accgtcgtca cctcgcggga
     3001 ttgccagcgc atcgcttctt ctgcaccatc gtaatggatt gcgcatcgtt gataacattc
     3061 acaaaaagtg acctcagcac cgcgcgccgt cagggtatcc ccaattagct cacgaccacc
     3121 attgccacgt aatatcagcg cacgtttgcc cgcaatattt tgtaattcag gtaattgtag
     3181 caagacttcg ctgatttccc gatcctgcgg gtagagaatc ttctgtccgc ttacggtatg
     3241 tagtgccagt gcggtggtgc gtccaatggc gaaataatca ggtagtcggg gccatttacg
     3301 atcttgctga tgcagctgtg attgggcaaa agcaaccgcg tgttgcgaga gggcaaacaa
     3361 cagatcgctc tcccccagcg ctgccagttg atcagcaagt tgcggtaatt gttgacccgg
     3421 agaaaactca atcagcggaa aatgccaggc cacctgcccc agtgtgcgca gacggctcac
     3481 taactcttct ccagcgggag acgggcgggt gacaaggata ctcatgccgg ggcgtctccg
     3541 ttatagactt cagcgaggat ctcgcgcgcg ccgttattca gtagctcttc tgccagcgaa
     3601 atccccattt gttcggcatc ttgcggcgca ccgcggcgtt caccgcgaat aatctgcgaa
     3661 ccgtccggcg cgccgaccag cgcacgcagc cagatttcgc catcaataag ctcggcgtag
     3721 ctaccaattg gcacctgaca tccgccttcg agacgggtat tcatggcgcg ttctgcggta
     3781 acgcgcagtg cagtttcgtg gtgattcagc gcggcaagca gctcgcgagt gcgtgaatca
     3841 tcaaggcggc attcaatacc caccgcacct tgtcctaccg ccggaagaga aatctcgggt
     3901 ggcaacgcgg cgcgaatacg tgactccaga cctaaacgtt ttagtccggc tacggcaaga
     3961 atgatggcat cgtattcgcc gttatccagt ttgctcaggc gagtgccgac gttgccgcgc
     4021 agggagcgga taatcagatc cggacggcgt tcagccagtt ggcactggcg acgtaaactg
     4081 gacgtcccga cgatactgcc tgccggtaac gcatccagac tgtcatagtt attggacaca
     4141 aaggcatcgc gaggatcttc acgctcacaa atagtgacca gtcccagacc ttgcgggaat
     4201 tcaaccggca catctttcat tgagtgtacg gcgatatcgg cgcgattttc gaggagcgcg
     4261 acttccagct cttttacaaa taagcctttt ccgcctactt tcgccagcgg cgtatcaaga
     4321 atcacatcgc cgcgcgtcac catcggtacc agttcaacga ccaggcccgg atggctcgcc
     4381 atcaacttgt ctttgacata gtgtgcctgc cagagtgcaa gtgggctttg gcgtgtggca
     4441 attcttaaaa cattgtctaa catgcttgtt accgtcatta tcatccgtgg tccatcctaa
     4501 catccttgcc agagtgatgt cagtgttgtg gtgaaacgta gacgcctgcg caaaccgtaa
     4561 aatgaggtct ggcagtggat cctgacaggc gtttcacgcc gttgtaataa ggaatttaca
     4621 gagaataaac ggtgctacac ttgtatgtag cgcatctttc tttacggtca atcagcaagg
     4681 tgttaaattg atcacgtttt agaccatttt ttcgtcgtga aactaaaaaa accaggcgcg
     4741 aaaagtggta acggttacct ttgacatacg aaatatcccg aatgccgcgt gttaccgttg
     4801 atgttggcgg aatcacagtc atgacgggta gcaaatcagg cgatacgtct tgtacctcta
     4861 tattgagact ctgaaacaga gactggatgc cataaatcaa ttgcgtgtgg atcgcgcgct
     4921 tgctgctatg gggcctgcat tccaacaggt ctacagtcta ctgccgacat tgttgcacta
     4981 tcaccatccg ctaatgccgg gttaccttga tggtaacgtt cccaaaggca tttgccttta
     5041 cacgcctgat gaaactcaac gccactacct gaacgagctt gaactgtatc gtggaatgtc
     5101 agtacaggat ccgccgaaag gtgagcttcc aattactggt gtatacacca tgggcagcac
     5161 ctcgtccgta gggcaaagtt gttcctctga cctggatatc tgggtctgtc atcaatcctg
     5221 gctcgatagc gaagagcgcc aattgctaca acgtaaatgt agcctgctgg aaaactgggc
     5281 cgcctcgctg ggtgtggaag tcagcttctt cctgattgat gaaaaccgct tccgtcataa
     5341 tgaaagcggc agcctggggg gcgaagattg tggctccacc cagcatatac tgctgcttga
     5401 cgaattttat cgtaccgccg tgcgtctcgc cggtaagcgt attctgtgga atatggtgcc
     5461 gtgcgacgaa gaagagcatt acgacgacta tgtgatgacg ctttacgcgc agggcgtgct
     5521 gacgccaaat gaatggctgg atctcggtgg cttaagctcg ctttctgctg aagagtactt
     5581 tggtgccagc ctttggcagc tctacaagag tatcgattcc ccatacaaag cggtactgaa
     5641 aacactgctg ctggaagcct attcctggga atacccgaac ccacgtctgc tggcgaaaga
     5701 tatcaaacag cgtttgcacg acggcgagat tgtatcgttt ggtctcgatc catactgcat
     5761 gatgctggag cgtgttactg aatacctgac ggcgattgaa gattttaccc gtctggattt
     5821 agtacgtcgc tgcttctatt taaaagtgtg cgaaaagctc agccgtgaac gcgcctgcgt
     5881 aggctggcgt cgcgcagtgt tgagccagtt agtgagcgag tggggttggg acgaagctcg
     5941 tctggcaatg ctcgataacc gcgctaactg gaagattgat caggtgcgtg aggcgcacaa
     6001 cgagttgctc gacgcgatga tgcagagcta ccgtaatctg atccgctttg cgcgtcgcaa
     6061 taaccttagc gtctccgcca gtccgcagga tatcggcgtg ctgacgcgta agctgtatgc
     6121 cgcgtttgaa gcattaccag gtaaagtgac gctggtaaac ccgcagattt cacccgatct
     6181 ctcggaaccg aatctgacct ttatttatgt gccgccgggc cgggctaacc gttcaggttg
     6241 gtatctgtat aaccgcgcgc caaatattga gtcgatcatc agccatcagc cgctggaata
     6301 taaccgttac ctgaataaac tggtggcgtg ggcatggttt aacggcctgc tgacctcgcg
     6361 cacccgtttg tatattaaag gtaacggcat tgtcgatttg cctaagttgc aggagatggt
     6421 cgccgacgtg tcgcaccatt tcccgctgcg cttacctgca ccgacaccga aggcgctcta
     6481 cagcccgtgt gagatccgcc atctggcgat tatcgttaac ctggaatatg acccgacagc
     6541 ggcgttccgc aatcaggtgg tgcatttcga tttccgtaag ctggatgtct tcagctttgg
     6601 cgagaatcaa aattgcctgg taggtagcgt tgacctgctg taccgcaact cgtggaacga
     6661 agtgcgtacg ctgcacttca acggcgagca atcgatgatc gaagccctga aaactattct
     6721 cggcaaaatg catcaggacg ccgcaccgcc agatagcgtg gaagtcttct gttatagcca
     6781 gcatctgcgc ggcttaattc gtactcgcgt gcagcaactg gtttctgagt gtattgaatt
     6841 gcgtctttcc agcacccgcc aggaaaccgg gcgtttcaag gcgctgcgcg tttctggtca
     6901 aacctggggg ttgttcttcg aacgcctgaa tgtatcggta cagaaactgg aaaacgccat
     6961 cgagttttat ggcgcgattt cgcataacaa actgcacggc ctgtcagtgc aggttgaaac
     7021 caatcacgtc aaattaccgg cggtggtgga cggctttgcc agcgaaggga tcatccagtt
     7081 ctttttcgaa gaaacgcaag acgagaatgg ctttaatatc tacattctcg acgaaagcaa
     7141 ccgggttgag gtatatcacc actgcgaagg cagcaaagag gagctggtac gtgacgtcag
     7201 tcgcttctac tcgtcatcgc atgaccgttt tacctacggc tcaagcttca tcaacttcaa
     7261 cctgccgcag ttctatcaga ttgtgaaggt tgatggtcgt gaacaggtga ttccgttccg
     7321 cacaaaatct atcggtaaca tgccgcctgc caatcaggat cacgatacgc cgctattaca
     7381 gcaatatttt tcgtgatgaa cgtgccggaa agcgaggctt atccggcatg caatcttagc
     7441 ggaaactgac tgtttcaccc gcctgctgcg tcgccgcctg ttccagcaaa tcccagaagg
     7501 tttcgccgct gcgatcacaa atccactcat cgcctttcag gtcaaaatgg tagccgccct
     7561 gtttggttgc cagccatacc tggtgcagcg gctcctggcg gttgataatg attttgctgc
     7621 cattctcaaa ggtaatggtc agtacgccgc cgttgatttc gcagtcgata tcgctgtcgc
     7681 catcccagtc gtccaggcgt tcttcaatgg tcagccagag ttgatcagcc aggcgatgaa
     7741 attcactgtc gttcattgtt gtatcctgtt tttaagtgat ggcggcagta tagcggcatg
     7801 gggtcagggc ttcaaagttt gcacctctgc ggctgcgttc cggcacgatt catccgtcac
     7861 cggaataatg atgtctctgt gtagcgaaag atttgtctct tcattagggc gcagttacac
     7921 cacgtctttc cctgtttctg gtaaacatta tgatcaggtt taccgagcga gcatcctcac
     7981 gctgacggaa ctaaaaaaga caacaaacaa accacattgc gatagtgcat aaagccatcc
     8041 tggcgcgagg tgccgatcac gaaactacca gcaaaacata aatccccacg agtaagcgtt
     8101 atactcgcag catttcctca cttttcagac ttcataaaga gtcgctaaac gcttgctttt
     8161 acgtcttctc ctgcgatgat agaaagcaga aagcgatgaa ctttacaggc aatccataat
     8221 gaaaaacgtg tttaaggcac tcactgtatt acttactctc ttcagcctga cgggctgcgg
     8281 tctgaaaggt ccgctctatt tcccgcctgc agataaaaac gcaccgccgc cgaccaaacc
     8341 ggtagagacg caaacgcaat ccacggtgcc ggataaaaac gatcgcgcca ctggcgatgg
     8401 tccatcccag gtgaattact aaaagtcagt ttctgtaccc gcgtgattgg agtaaatgat
     8461 gcagttctcg aaaatgcatg gccttggcaa cgattttatg gtcgtcgacg cggtaacgca
     8521 gaatgtcttt ttttcaccgg agctgattcg tcgcctggct gatcggcacc tgggggtagg
     8581 gtttgaccaa ctgctggtgg ttgagccgcc gtatgatcct gaactggatt ttcactatcg
     8641 cattttcaat gctgatggca gtgaagtggc gcagtgcggc aacggtgcgc gctgctttgc
     8701 ccgttttgtg cgtctgaaag gactgaccaa taagcgtgat atccgcgtca gcaccgccaa
     8761 cgggcggatg gttctgaccg tcaccgatga tgatctggtc cgcgtaaata tgggcgaacc
     8821 caacttcgaa ccttccgccg tgccgtttcg cgctaacaaa gcggaaaaga cctatattat
     8881 gcgcgccgcc gagcagacaa tcttatgcgg cgtggtgtcg atgggaaatc cgcattgcgt
     8941 gattcaggtc gatgatgtcg ataccgcggc ggtagaaacg cttggtcctg ttctggaaag
     9001 ccacgagcgt tttccggagc gcgccaatat cggttttatg caagtggtta agcgcgagca
     9061 tattcgttta cgcgtttatg agcgtggggc aggagaaacc caggcctgcg gcagcggcgc
     9121 gtgtgcggcg gttgcagtag ggattcagca aggtttgctg gccgaagaag tacgcgtgga
     9181 actccccggc ggtcgtcttg atatcgcctg gaaaggtccg ggtcacccgt tatatatgac
     9241 tggcccggcg gtacatgtct acgacggatt tattcatcta tgaagcaacc aggggaagaa
     9301 ctgcaggaaa cactcacgga gcttgatgac cgggcggttg tcgattatct gattaaaaat
     9361 cctgagtttt ttatccgtaa tgcgcgcgca gtagaagcga tacgtgtgcc gcatccggta
     9421 cgcggcaccg tttcgttggt cgagtggcac atggcccgcg cacgtaatca tattcatgtt
     9481 ctggaagaga acatggcgct gttgatggaa caggctatcg ccaacgaagg cctgttttat
     9541 cgcctactct acctgcagcg cagtctcacc gccgccagca gtctcgacga tatgctgatg
     9601 cgctttcacc gctgggcgcg cgatctcggc ctggcaggtg cgagtctgcg cctgtttccg
     9661 gatcgctggc gcttaggtgc gccgtcgaac cacactcatc tggcattaag ccgtcagtct
     9721 ttcgaaccgc tgcgtattca gcgtttgggg caggaacagc actatcttgg gccgcttaac
     9781 ggaccagagc tgctggtggt gctaccggaa gcgaaagcgg tgggatcggt ggcgatgtcg
     9841 atgctgggaa gcgatgctga tttgggtgtc gtgctgttta ccagtcgcga tgccagtcac
     9901 tatcaacaag ggcaaggaac gcagttactt catgaaattg cgctgatgtt gccggagctt
     9961 ctggagcgtt ggattgaacg cgtatgaccg atttacacac cgatgtagaa cgctacctac
    10021 gttatctgag cgtggagcgc cagcttagcc cgataaccct gcttaactac cagcgtcagc
    10081 ttgaggcgat catcaatttt gccagcgaaa acggcctgca aagctggcag caatgtgatg
    10141 tgacgatggt gcgcaatttt gctgtacgca gtcgccgtaa agggctggga gcagcaagtc
    10201 tggcgttacg gctttctgcg ctacgtagct tttttgactg gctggtcagc cagaacgaac
    10261 tcaaagctaa cccggcgaaa ggtgtttcgg caccgaaagc gccgcgtcat ctgccgaaaa
    10321 acatcgacgt cgacgatatg aatcggctgc tggatattga tatcaatgat cccctcgctg
    10381 tacgcgaccg tgcaatgctg gaagtgatgt acggcgcggg tctgcgtctt tctgagctgg
    10441 tggggctgga tattaaacac ctcgacctgg agtctggtga agtgtgggtt atggggaaag
    10501 gcagcaaaga gcgccgcctg ccgattggtc gcaacgctgt ggcgtggatt gagcactggc
    10561 ttgatttgcg cgacctgttt ggtagcgaag acgacgcgct ttttctgtcg aaactgggca
    10621 agcgtatctc cgcgcgtaat gtgcagaaac gctttgccga atggggcata aaacaagggc
    10681 tgaataatca cgttcatccg cataaattac gtcactcgtt cgccacgcat atgctggagt
    10741 cgagcggcga tcttcgtggt gtgcaggagc tgctgggtca tgccaacctc tccaccacgc
    10801 aaatctatac tcatcttgat tttcaacacc ttgcctcggt gtacgatgcg gcgcatccac
    10861 gcgccaaacg ggggaaataa tgcgttttta ccggcctttg gggcgcatct cggcgctcac
    10921 ctttgacctg gatgataccc tttacgataa ccgtccggtg attttgcgca ccgagcgaga
    10981 ggcgcttacc tttgtgcaaa attatcatcc ggcgctgcgc agcttccaga atgaagatct
    11041 gcaacgcctg cgccaggcgg tacgggaagc ggaacccgag atttatcacg acgtgacgcg
    11101 ctggcgtttt cgttcgattg aacaagcgat gctcgacgcc gggctgagtg ccgaagaagc
    11161 cagtgcaggc gcacacgcag caatgatcaa ctttgccaaa tggcgcagcc gaatcgacgt
    11221 cccgcagcaa actcacgaca ccttaaaaca gctggcgaag aaatggccgc tggtggcgat
    11281 caccaacggt aacgcccagc cggagctgtt tggtttgggg gattattttg agtttgtgct
    11341 gcgcgctggc ccgcacgggc gctcaaaacc gttcagcgat atgtactttt tggctgcgga
    11401 aaaactcaac gtgccgatcg gcgagatctt acatgttggg gacgatctca ccactgacgt
    11461 gggtggggca attcgcagcg gaatgcaggc ttgttggatc agaccggaaa atggcgatct
    11521 gatgcaaacc tgggacagcc gtttactgcc gcatctggaa atttcccggt tggcatctct
    11581 gacctcgctg atataatcag caaatctgta tatataccca gctttttggc ggagggcgtt
    11641 gcgcttctcc gcccaaccta tttttacgcg gcggtgccaa tggacgtttc ttacctgctc
    11701 gacagcctta atgacaaaca gcgcgaagcg gtggccgcgc cacgcagcaa ccttctggtg
    11761 ctggcgggcg cgggcagtgg taagacgcgc gtactggtgc atcgtatcgc ctggttgatg
    11821 agcgtggaaa actgctcgcc atactcgatt atggcggtga cgtttaccaa caaagcggcg
    11881 gcggagatgc gtcatcgtat cgggcaactg atgggcacga gccagggcgg tatgtgggtc
    11941 ggcaccttcc acgggctggc gcaccgtttg ctgcgtgcgc accatatgga cgccaatctg
    12001 ccgcaggatt tccagatcct cgacagtgaa gaccagctac gcctgcttaa gcgtctgatc
    12061 aaagccatga acctcgacga gaagcagtgg ccgccgcggc aggcaatgtg gtacatcaac
    12121 agccagaaag atgaaggcct gcgtccgcat catattcaaa gctacggtaa tccggtggag
    12181 cagacctggc agaaggtgta tcaggcgtat caggaagcgt gtgaccgcgc gggcctggtg
    12241 gacttcgccg agctgctgct gcgcgctcac gagttgtggc ttaacaagcc gcatatcctg
    12301 caacactacc gcgaacgttt taccaatatc ctggtggacg aattccagga taccaacaac
    12361 attcagtacg cgtggatccg cctgctggcg ggcgacaccg gcaaagtgat gatcgtcggt
    12421 gatgacgacc agtcaatcta cggctggcgc ggggcgcagg tggagaatat tcagcgtttc
    12481 cttaatgatt tccccggtgc cgaaactatt cgtctggagc aaaactaccg ctctaccagc
    12541 aatattctga gcgccgctaa cgccctgatt gaaaacaata acgggcgtct gggtaaaaaa
    12601 ctgtggaccg atggcgcgga cggtgagcct atttccctct attgcgcttt taacgaactc
    12661 gatgaagcgc gttttgtggt taaccgcatc aaaacctggc aggacaacgg cggagcgctt
    12721 gccgagtgcg ccattctcta ccgcagcaac gcccagtcgc gggtgctcga agaggcgtta
    12781 ttgcaggcca gtatgccgta ccgtatttac ggcgggatgc gcttcttcga acgccaggaa
    12841 atcaaagatg cgctctcgta tctgcgcctg attgccaacc gcaacgacga cgcggccttt
    12901 gagcgtgtgg tgaatacgcc aacgcggggt attggtgacc ggacgctgga cgtggtacgt
    12961 cagacatcgc gcgatcgcca gttaacactc tggcaggcat gtcgtgagct gttgcaggaa
    13021 aaagccctcg ccgggcgagc tgccagcgcc ttgcagcgat ttatggaatt aatcgacgcc
    13081 ttagcgcagg aaactgccga tatgccgctg catgtacaga ctgaccgggt aattaaagac
    13141 tccggcctgc gtaccatgta tgagcaggag aagggcgaaa aaggtcagac gcgtatcgaa
    13201 aacttagagg aactggtgac ggcaacgcgc cagttcagct acaacgaaga agacgaagat
    13261 ttaatgccgc tgcaggcgtt cctctcccat gcggcactgg aagcaggtga agggcaggcg
    13321 gatacctggc aggatgcggt gcagttgatg acgctacact cggcgaaagg cctggagttc
    13381 ccgcaggtgt ttatcgttgg tatggaagag ggcatgttcc caagccagat gtcgctggat
    13441 gaaggcgggc gtctggaaga agaacgccgt ctggcctacg ttggcgtaac ccgcgcgatg
    13501 cagaaactga cgctgaccta cgcggaaacc cgccgtctgt atggtaaaga ggtttaccat
    13561 cgcccgtcgc gctttatcgg cgagctgccg gaagagtgtg tggaagaggt gcgcctgcgc
    13621 gccacggtaa gccgcccggt cagccatcag cggatgggta cgccgatggt cgagaacgac
    13681 agcggctaca agctcggcca gcgcgtacgc cacgctaagt ttggtgaagg caccattgtc
    13741 aatatggaag gcagcggtga gcatagccgt ttgcaggtgg catttcaggg ccagggtatt
    13801 aaatggctgg tggcggcata cgcccggctg gagtcggtgt aacgttgccg gatgcggtgc
    13861 tgcgcacctt atttggccta aaaaatcatt cagattcaat aaattgcaac gtcatgtagg
    13921 ccggataggg cgtttacgcc gcatccggca tctgcgccat cttcagtatc tgacacaaaa
    13981 ctatcgtttt aacctttccg ctcgacggaa atcatggtga caaaaggata gcgttgccac
    14041 gggattgccc cgcctttcat atacatatgt gaaatcgtgc catcaagata aagcagctgc
    14101 tcaacgttca gtttcgcttt ggcataacag gcaaaatcat aaaaatttgt tgcctgctgg
    14161 ctcaacaaaa acacggcgtt cccatgttta ttaatcccaa caccgttacg aattttgctt
    14221 gaggcgacgt tgggatgaat acgcggatta attacaccgt tttccatcaa cattggccct
    14281 gactgcaccg caaactgaat ctctttactg gttttgaagg catccagacg aacgatgccg
    14341 actttatctc ccgcgacata aaacacgccg ccaggacgga taaagaaatt cccttcacct
    14401 gaagcgagat ttaacgccac cttctgctga ccgttttcga tgtacaaacc gagcggcgca
    14461 tagctttcat catagatgcc gccgttcatc gccatctgca cctgaccctg actattaata
    14521 tccgccagca gagcatgtaa cgttccccac gcttcgccat tggctttttg ccagtacatt
    14581 ttcacccgct ctgtttgagg attaacggta tacgcctgta cggtcagcgt cggatctgag
    14641 agtgcgcaat catcagcggc aacagcaaac aagggaagta aggtgagggc gagaaaaatc
    14701 cgtttgagat tcaaggtgat cattccttta ccaatgagta gctgatgcgc cattataggt
    14761 cctggatgtg ggattttttt atcctgttag cgaccttgac gagtaccaaa aagcgcgaag
    14821 ttcaactatt gttctgtggt gttctgttgc gtgttgacgg caaaattttg ctggcgtaac
    14881 atgcgcgcac gatcactcta agaggacatt cgccttggac acacccagta gatactggct
    14941 cactatcctg tcatccagga tcaactccta aggctatccc tttttgctga tagccttagc
    15001 ggttgtcagc gacctcaatt tttcccgtcg cgctgagtca ggctgtttaa tggtctgaaa
    15061 cccaatttgt ttctgtgtgc ccaccgaact gtccgatatt ttaagcattg ggagtcccgg
    15121 tcatgctgag cgcatttcaa ctggaaaata accgactgac ccggctggaa gtcgaagagt
    15181 cacaacccct tgtaaatgca gtatggattg atcttgtcga accggacgac gacgagcgac
    15241 tgcgcgtaca atctgaactt ggccagagcc tggcaacccg cccggaactg gaagacatcg
    15301 aagcatcggc acgtttcttt gaagacgacg acggcctgca tattcactcc ttcttcttct
    15361 ttgaagatgc ggaagatcac gccggtaact ccactgtggc atttaccatc cgtgatggtc
    15421 gtctgtttac tctgcgtgag cgtgaactgc ccgcttttcg tctgtatcgt atgcgtgccc
    15481 gtagccagtc gatggtagac ggtaacgcct acgagttgct gctggatctg ttcgaaacca
    15541 aaatcgaaca gttggcagat gaaattgaaa atatctatag cgacctggag cagttgagcc
    15601 gggtgattat ggaagggcat cagggcgatg agtacgacga ggcgctctcc actctggcgg
    15661 aactggaaga tatcggctgg aaagttcgcc tgtgtctgat ggatacccag cgcgcgctca
    15721 acttcctggt gcgtaaagcg cgtttaccgg gtgggcaact ggagcaggcg cgtgaaatcc
    15781 tgcgagatat cgaatccctg ctgccgcata acgaatccct gttccagaag gtgaacttcc
    15841 tgatgcaggc ggcaatgggt tttatcaaca tcgagcagaa ccgcatcatc aaaatcttct
    15901 cggtggtatc cgtggtattc ctgccgccga cgctcgttgc ttccagctat ggcatgaact
    15961 ttgagtttat gccagaactg aagtggagct tcggctaccc tggcgcgatt atctttatga
    16021 tcctcgcggg cctggcaccg tatctgtact ttaagcggaa gaactggttg taaaaaacga
    16081 gagcggtggc ttagtctggc taagccacct gttattcaaa ggctccaggt atttaaccct
    16141 tttacctctt tctcatagaa ccatttgttc gtgttaacag caacataggc tgctacggca
    16201 attcccagaa tgttaacgcc aattagtgca ccaacaaata gagatagaat accaagtaat
    16261 agaactataa ttgctttttt ccataacccc aggacaaata aatatatcca ggaacagaag
    16321 aaagcaatga aattcatttg aatagttaag cgttgtctta cttttaatgc tttaaatgct
    16381 gctttatatt ctggtgttgc cccccagaat ccaggaaaac tatgttgatc ataaaaatta
    16441 aatcggtatt tccatttttc acttaatgaa ccatcgttca tatattcctt actcataaat
    16501 actccataac tattgttttg atgaatcagt aggtgcaagc attagcatac tgaaagtgga
    16561 aaaataacaa atcaaaaaaa tcatcgaacc attgcctgaa caggcaaaat cttcggctat
    16621 cattgtgatg atagagatga tatatactgc taatgtacca aaaacataag tttttatata
    16681 gatgaaacca ctatcacgga gtcgctggca attcatgttg atgacgagat aatggagtac
    16741 gatggtagag actataacaa gaaagcctgc ttctccatcg ttaaaaaaga taataagaaa
    16801 ggcaaaaatg aaatttatta aaataaatga aaatatataa cgacgtctgg aaatcttacc
    16861 gttagatgtt gggataaata tacgtaacat aaattttaca tccttgtatg agtctccggt
    16921 cagcatggca ata
//
LOCUS       DAPHKZ010000097        16468 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.097, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000097 DAPHKZ010000000
VERSION     DAPHKZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16468
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.097"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(19..171)
                     /locus_tag="RH288_003318"
     CDS             complement(19..171)
                     /locus_tag="RH288_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDV4032349.1"
                     /translation="MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVL
                     AYESKK"
     gene            complement(436..1170)
                     /gene="cysH"
                     /locus_tag="RH288_003319"
     CDS             complement(436..1170)
                     /gene="cysH"
                     /locus_tag="RH288_003319"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDV4032350.1"
                     /translation="MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNL
                     PGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLK
                     VYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTT
                     RKWEPGMSEEETRFFGLKRECGLHEG"
     gene            complement(1244..2956)
                     /gene="cysI"
                     /locus_tag="RH288_003320"
     CDS             complement(1244..2956)
                     /gene="cysI"
                     /locus_tag="RH288_003320"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HDV4032351.1"
                     /translation="MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKF
                     AGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPI
                     RPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRI
                     TANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERF
                     LPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGN
                     RIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DLWD"
     gene            complement(2956..4755)
                     /gene="cysJ"
                     /locus_tag="RH288_003321"
     CDS             complement(2956..4755)
                     /gene="cysJ"
                     /locus_tag="RH288_003321"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HDV4032352.1"
                     /translation="MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVL
                     NQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYK
                     FKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSV
                     ATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYAT
                     LTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIAS
                     SQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPAN
                     PETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKE
                     GVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQAL
                     LEVIAEFGGMDTEAADEFLSELRVERRYQRDVY"
     gene            5074..5436
                     /gene="queD"
                     /locus_tag="RH288_003322"
     CDS             5074..5436
                     /gene="queD"
                     /locus_tag="RH288_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708563.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HDV4032353.1"
                     /translation="MSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCIYRGE"
     gene            5514..6785
                     /locus_tag="RH288_003323"
     CDS             5514..6785
                     /locus_tag="RH288_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417246.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDV4032354.1"
                     /translation="MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNL
                     SGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGVTTFSSLQPGGESWSVLRA
                     RFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
                     AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGRICDDLPGGA
                     FLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVP
                     EGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHRE
                     PQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKP
                     VPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL"
     gene            6776..7036
                     /locus_tag="RH288_003324"
     CDS             6776..7036
                     /locus_tag="RH288_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417247.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HDV4032355.1"
                     /translation="MSVARNLWRVADAPHIVPADSVERQTAERLINACPAGLFSLTPE
                     GNLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG"
     gene            7053..7628
                     /locus_tag="RH288_003325"
     CDS             7053..7628
                     /locus_tag="RH288_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HDV4032356.1"
                     /translation="MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTIS
                     NIVKKIKNAGKYAYIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGF
                     FCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVC
                     DEEDARNAINAGVVALSTTNTGVWTLAKKLL"
     gene            complement(7776..8636)
                     /locus_tag="RH288_003326"
     CDS             complement(7776..8636)
                     /locus_tag="RH288_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417249.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDV4032357.1"
                     /translation="MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQV
                     LDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHW
                     GNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNV
                     TRAPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISG
                     HLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEA
                     LVTNIHADCQ"
     gene            complement(8633..9412)
                     /locus_tag="RH288_003327"
     CDS             complement(8633..9412)
                     /locus_tag="RH288_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417250.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDV4032358.1"
                     /translation="MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADE
                     QAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPE
                     FVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFI
                     TLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPA
                     MQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP"
     gene            complement(9390..10799)
                     /locus_tag="RH288_003328"
     CDS             complement(9390..10799)
                     /locus_tag="RH288_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4032359.1"
                     /translation="MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRI
                     AALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWIS
                     DHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFS
                     PRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWG
                     TPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFN
                     SVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHR
                     KFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIR
                     SLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKA
                     LPLVAAGNVGGANEHSVSV"
     gene            complement(10821..12275)
                     /locus_tag="RH288_003329"
     CDS             complement(10821..12275)
                     /locus_tag="RH288_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDV4032360.1"
                     /translation="MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHG
                     IYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDG
                     SAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
                     IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITE
                     VTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHF
                     ADGKCVLIFMAEGNPRIAKVTGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVA
                     AERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQ
                     NGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWS
                     KLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK"
     gene            complement(12345..13130)
                     /locus_tag="RH288_003330"
     CDS             complement(12345..13130)
                     /locus_tag="RH288_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417254.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV4032361.1"
                     /translation="MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGAN
                     IFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNA
                     GICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
                     QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVL
                     DHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR"
     gene            13449..14726
                     /locus_tag="RH288_003331"
     CDS             13449..14726
                     /locus_tag="RH288_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4032362.1"
                     /translation="MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSN
                     TEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVML
                     CIQIAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFS
                     RFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVL
                     RISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPL
                     GGIITTYSKVKSPTRVIQILSVLGLLTLTALLVTNSNPQSVAMGIGLILLLGFTCYAS
                     RGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWL
                     MGMAALGMVIVFTFLLFQKIRTADSAPAMASSK"
     gene            14753..16231
                     /locus_tag="RH288_003332"
     CDS             14753..16231
                     /locus_tag="RH288_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDV4032363.1"
                     /translation="MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDAD
                     TAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLIS
                     WQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSED
                     AAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAG
                     LLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSW
                     LRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMI
                     GFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFA
                     DVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDNMVRVKDIFIPIESNAKRY
                     DAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA"
BASE COUNT         3911 a         4348 c         4154 g         4055 t
ORIGIN      
        1 tttacccccg cgtggtggct acttcttcga ttcgtaagcg agaactgcct taaactccat
       61 accacgttct ctgatactca actcacacaa cgagtcgcct accatcagcg tgaatcccag
      121 tactgtaaaa cacagcacta tgattgccac aagggcatat tttgtcagca tgtcttgcct
      181 ccctgcaaag aagagactaa cattcgaatt gtttgggttc gaacgtaagc ctcaggttga
      241 tagaaatatc gcctggggct tttgtccatc tggaacctcg cgaatgctta acgccagaca
      301 gcctcaagca cccgacgcca ttctatacct gataattctt ccagcggcgt tcacgtttaa
      361 aatcaggaat actgctcgca aaataaaaac gcccccatca tttctgacag aggcgtttaa
      421 tttatccggc aatatttacc cttcgtgcaa tccacattcc ctttttaagc caaagaaacg
      481 tgtttcttct tccgacatgc caggttccca tttacgggtt gtatgggtat caccgaccga
      541 taaatatcct tcatcccata atgggtgata tttcaggcca tgtttttgca ggtactgata
      601 aatagttcgg ttatcccagt cgataatcgg cagcacttta aatacgccac gctgaattgc
      661 cagcaccggt aaattggcgc ggctgccgga ttgttcgcgg cgcaggccag caaaccaggt
      721 ttgcgcgtta agttctttca gcgcccggtt catcggttcg actttgttga tgtcattgta
      781 cttttcaatg ccttcaacgc cctgttccca cagtttgccg tagcgtgctt cctgccaggc
      841 ggcgctttcg gtagcacggt acactttcag gttgagcttg agtttgtccg ttaactcgtc
      901 aataaagcgg taggtttccg gaaacagata accggtatcg gtgaggatca ctggaatatc
      961 cggccgaatc tgattcacca gatgcaggct caccgccgcc tgaatgccga agctggaaga
     1021 aagcacatat tcaccgggca gattatccag cgcccaggct acgcggcctt cagcgtccag
     1081 tttttccagt tgggcgttag tttccgccag cgccagaatg cgatctacct tcggcagttc
     1141 gttcagggcg tttagatcga gtttggacat agattcctca ctgtttgcct tgcctgatgc
     1201 gacgctcacg cgtcttatca ggcctacaag accgggctga tggttaatcc cacaaatcgc
     1261 gcgccggatc gagcaccggg cgaatgatgc ccgcacgcac cgtaaagtcg ccgaagcctt
     1321 cacccgcttc gcgctctttc gcccagcgcc ctatcagttc atcaagcgac gccaggattt
     1381 ccggctcggt gatgttttct ttatacatcc gagggatacg tgtcccaatg cggttgccgc
     1441 caagatgcag gttgtagcga cccggcgctt tacccaccag gcccacttcc gccagcatcg
     1501 cgcgaccaca accgttcggg cagcctgtta cacgcatcac gatatgctca tcgctgacac
     1561 catgtttcgc cattaaatta tcgatgttgt cgataaaaga cggcaggaaa cgctccgctt
     1621 ccgccatcgc cagcgggcaa gtcgggaatg acacgcaggc cattgagttt tcacgctgcg
     1681 gcgtgacggc attcattaac ccgctctctt tggcgatctt ctcgatcttc gctttctcgc
     1741 tttccggtac accggcgatg atcagattct ggttcgccgt aatgcggaaa tcgcctttgt
     1801 ggatcttcgc gatctccagc aggccggttt tcagcggacg cgccggataa tcaaggatgc
     1861 gaccattttc gataaacagc gtcaggtgcc agttatcatc aatgccctta acccagccaa
     1921 tacgatcgcc tcgtccggtg aactcatatg gacggatcgg ttcaaatttg atccccgcgc
     1981 gacgctccac ttccgcttta aacgtctcaa cccccacgcg ctccagcgtg tatttggttt
     2041 tggcattttt acgatcggtt cggttacccc agtcacgctg agttgtcacg acggcttcgg
     2101 ccaccgccag cgtatgctcc agcggcagat agccaaactc actcgcggtg cgggcgtagg
     2161 ttttcttgtt gccgtgttcg atggaaagcc caccgcccac caacaggtta aagcccacca
     2221 gcttgccgtt ttcggcgatc gccacgaagt tcatgtcgtt ggcgtgcaga tcgatatcgt
     2281 tctgtggcgg gatcactacc gtggttttga atttacgcgg caggtaggtc tggccgagga
     2341 tcggttcttc atcagtagtg gcgacttttt cctggtcgag ccagatctcc gcatacgcgc
     2401 gggtacgcgg cagcagatgc tcagaaatct tcttcgccca ctcgtacgct tccgcgtgta
     2461 gctgcgactc gtaagggttc gaggtgcaga gtacgttacg gttcatgtcg ttagcggtcg
     2521 ccagcgcatc aagaccaacc gagtgcagca tctggtgcac cggtttgacg ttctttttca
     2581 gaatgccgtg gaactgaaac gtctggcggt tggtcaggcg aatgctgcca tagatggtgt
     2641 tttcaccggc aaatttgtct atcgcctgcc actgtttagt ggtaatcacc ccacccggca
     2701 gacggcagcg caacagcatc gcgtggcgcg gctccagctt ctgttcagca cgttcggcgc
     2761 ggatgtcgcg gtcatcctgc tgatacatgc cgtggaagcg gatcagcagg aagttgtcgc
     2821 ccttaaagcc gccggtcaga ccgtcgttta aatcttccgc aatggtgccg cgcaggtagt
     2881 tgctttcaag cttcatgcgc tcggcgtctg tcagttttcc ttcgaccact aaaggccctg
     2941 gatgtttttc gctcattagt agacatctcg ctgataacgg cgctctacgc gcagctcact
     3001 taaaaattca tccgccgctt cggtgtccat gccaccaaat tcggcaatca cttccagaag
     3061 tgcctgctca acgtctttcg ccatgcgatt agcgtcaccg cagacataaa tgtgggcacc
     3121 gtcattgatc cagcgccaca gctccgcgcc ctgttcgcgc agtttgtctt gtacgtaaac
     3181 tttttctttt tggtcgcgcg accaggcgag atcgatccgc gtcagcacac cctctttgac
     3241 gtagcgctgc cactccacct ggtagaggaa atcttccgta aagtgcgggt tgccaaagaa
     3301 cagccagttt tttcccggcg cttcatcggc agcacgttgc tgcataaagg cgcggaacgg
     3361 cgcgatgccg gtgcctgggc caatcataat caccggggtt tctggattgg ctggcaggcg
     3421 gaagttatcg ttatgttcga taaatacgcg gacttcgccc tcttcttcca cgcggtcagc
     3481 gaggaagctg gaggcaccac cggcacgggc gcggccttcc acgtcgtaac gcaccacacc
     3541 aacggtgacg tgtacttcgt tctcgacttc cgcctgcgag gaggcaatgg aatagagacg
     3601 cggcgtcagc gggcgcagca gattaattag cgcttcggca tcaagctgtg ccggggagaa
     3661 acgcaccatg tcaacaatcg gcgtcgtcgc ggcgtaatgc tgtaacttcg ctttatcgcc
     3721 caccagcggc agcagtgttt cactgcgggt aagcgtggcg taattctcaa caatgttggc
     3781 ggtgttgacg gtcagttcga agtgccactg tagcgcttcg ttcagaggca acgttttgcc
     3841 ctcgacggtg acaggttcat cgcctttcag ccacagcagt tcgacaagtt ctttcaccag
     3901 tgccggatcg ttctgatacc agacgcccag cgcgtcaccc ggctggtaac gcaggcccga
     3961 gtcacctaag tcaatttcga tatggcgaac gtctttttca gagttacgcc cggtaatttt
     4021 ctggttaaca gagaggctag ccaccagcgg cgcgtctttg ctgtacgggc tggtgtggat
     4081 ttcatttacc gcgccagtag cgacggattg cgaaggtgcc gcgacaggcg cacgcgattt
     4141 aagcgcatca accacgcggg cgcgccactc gctggcagca gcctggtatt caacatcggc
     4201 atcgacacgg tcgagcaggc gttcaccacc cagttccgcc agcttgctgt cgaaatcttt
     4261 cccggactgg cagaaaaatt cataagagct atcgccgagg ctaaacacgg caaacgcggt
     4321 gttttccagc tttggcgctt ttttggagaa caggaactta tgcagcgcga cggcttcttc
     4381 cggcggttcc ccttcccctt gcgttgacgt cactacgatg agcagttttt cgctggcgat
     4441 ttgtttgaat ttatagtcgc ccgcgttcac cagcttaacg ttcagttttg ctgctaataa
     4501 atcatcacgt aatgcttcag caacccggcg cgcattgccg gtttgcgagg cggagataat
     4561 agttataccc ggcatttctg cggctggcgc tggcgtcgct gcaagcgcag caggctgctg
     4621 attgagtacg ccccagaaat agccagaaac ccaggcaagc tgggtgggag ttaaatcggt
     4681 cgtggccgcc tgaaggcgtg ccagttgctc cgggttcaac ggaagcaacg cggaaggtgg
     4741 gacctgtgtc gtcatgcgtc gttatgttcc agtaagcaaa gctgtttctg cgccctgtca
     4801 gcgcccataa aacagaagag aaggtaaggt taacggggca aacggtgtgg attaaagacg
     4861 ggatagcgat aactaataac caaatcgact aacctgtttt agcaatagtc tttaacaaca
     4921 aaatagatta accaacctaa tgaaaaacaa atgaatttag ccaatcatta agataaatca
     4981 gcgattttgc gcaacaaagt cgttttagat aatgcgaaaa aacagccttt ccggtactct
     5041 acggcggttt tatcgtcctg tagagaaatt atgatgtcca ccacgttatt taaagatttc
     5101 accttcgaag ccgctcaccg cttaccacac gtcccggaag ggcataaatg tggtcgcctg
     5161 cacgggcatt cctttatggt gcgactggaa attaccgggg aagtcgatcc gcatacgggc
     5221 tggattatcg atttcgctga actaaaagcg gcgtttaaac caacctacga gcgcctcgat
     5281 caccattatc tcaatgatat tccaggtctg gaaaacccaa ccagcgaggt tttagcaaaa
     5341 tggatttggg atcaggttaa acccgttgtg ccgctgttaa gtgcggtgat ggtaaaagaa
     5401 acctgcaccg caggttgtat ctatcgcggc gaatgataag agtgtgtcgg cggtcaattt
     5461 cccttaagta acgctatgtt agggtgttgt gttctggata tctggggcat gacatggaag
     5521 acgactgcga cattattatt attggtgccg gtattgcagg caccgcttgc gcgttacgct
     5581 gcgcgcgagc gggtttatcc gttttgttac tggaacgcgc tgaaatcccc ggcagcaaaa
     5641 atctttccgg cgggcggtta tatacccatg cactcgcgga actcctcccg caatttcatc
     5701 tgaccgcgcc tcttgaacga cgcatcactc acgaaagcct ttccctgtta acgcccgatg
     5761 gcgtaacgac gttttccagc ttacagcccg gcggtgaatc ctggagtgta ttacgtgcac
     5821 gattcgatcc gtggctggtt gccgaagccg aaaaagaagg tgtcgaatgc atccccggag
     5881 cgacggtgga tgcactgtat gaagaaaacg gcagagtctg tggcgttatt tgtggtgacg
     5941 atattctccg cgcccgttat gtggtgctgg cagaaggtgc caacagcgtc ctggctgaac
     6001 gtcacgggtt agtgactcgt cctgctggcg aagcgatggc gttggggatc aaagaagtgc
     6061 tgtcgctgga aacatccgct attgaagaac gttttcatct ggagaataac gaaggcgcag
     6121 cgttgctgtt cagcggcagg atctgtgatg acttacccgg cggcgcattt ctttatacta
     6181 atcaacaaac gctctcgtta gggattgttt gcccgctctc ttcccttacg caaagtcgtg
     6241 ttccggcaag cgagctgctg actcgcttta aagcgcatcc ggcagtgcgc ccgcttatca
     6301 aaaacacgga atcactggag tatggtgcgc atctggtgcc agaaggtggc ttgcacagta
     6361 tgccggtgca atacgccggt aacggctggc tgctggtggg cgatgcgttg cgcagttgcg
     6421 tcaataccgg aatttccgtg cgcggcatgg atatggcgct gactggcgcg caggcggcgg
     6481 cacaaacgct gataagcgcc tgccagcacc gcgagccgca aaatctgttt ccgctttatc
     6541 atcacaacgt agagcgcagc ctgctgtggg atgttctaca gcgttatcag catgttccgg
     6601 cgcttttgca acgcccggga tggtaccgta cgtggcctgc gttaatgcag gatatttccc
     6661 gcgatttatg ggatcagggt gataaacctg ttccaccgct gcgccagtta ttctggcatc
     6721 atttacgtcg tcacggcctg tggcatctgg cgggcgatgt tatcaggagt ctgcgatgtc
     6781 tgtagcccgt aatctctggc gcgttgctga tgcgccgcac attgttccgg ctgactccgt
     6841 tgagcgccag acggcagaac ggttgattaa cgcctgtccg gcaggtcttt tttcgctcac
     6901 accggaaggt aacttacgta ttgactatcg cagttgcctg gagtgtggca cctgccgttt
     6961 gctgtgcgac gaatcaacac tacaacagtg gcgctatccg ccttccggat tcggcatcac
     7021 ctaccgcttt ggataaataa taaggataat ttatgcccct cttacacctg ctccgccaga
     7081 atccggtgat tgctgccgtt aaagataatg ccagcctgca actggcaatc gattctgaat
     7141 gccaatttat ttccgtgttg tacggcaata tctgcaccat cagtaatatc gttaaaaaga
     7201 ttaagaacgc cgggaaatat gcttatattc atgttgattt gctggaaggc gcgtcaaata
     7261 aagaagtcgt tattcagttt ttgaaactgg tgaccgaggc ggacggcatt atcagtacca
     7321 aagcctcaat gttgaaagcg gcaagagcgg aaggtttttt ctgtattcat cgcctgttta
     7381 ttgttgattc aatttcgttt cacaacattg ataagcaagt tgcgcaatcg aatccggatt
     7441 gtattgagat cctgccaggc tgtatgccca aagtgctggg ctgggtgaca gagaaaatcc
     7501 gccaaccgct gattgccggt gggctggtgt gcgatgaaga agatgcgcgt aatgcgatta
     7561 acgcgggtgt cgtggcgctt tccaccacga ataccggggt ctggacgtta gcgaaaaaat
     7621 tactttgacg ggataatcgt aaccaattga atttggtttg atttgtaggc cgcacgccac
     7681 atccgacatt cagcgcctga tgcgacgctt gacgcgtctt atcaggccta caagtcccca
     7741 ggccagaacc gtaggcagga tcatccggca acacgttatt ggcaatctgc gtgaatgttt
     7801 gtcaccagtg cctccagcac cactttccag tcatcaacca cgccaacatc tgcctgtgaa
     7861 aataccgcag cgctggcgtc atgattaatc gccaccacaa acttgctatt gcgtacgccc
     7921 gccattaacg ctgctgcgcc agaagcgcca acaacaatac acacctcagg tgccagcaga
     7981 tgtccggaaa taccaatcac tttttcagca tcaacgccac cgttcatcac tcgcgcccga
     8041 ctgtagccca cttcggctcc cagcttttct gccagcatag cgatttcctg gttatctgcc
     8101 tctccgccct gccccaccac cagcacccgt ctggcctcag ctaatggggc gcgggtaaca
     8161 tttttcagat cctctgtgct aaccagccag tccggaagcg cacccgggac aatgttcagt
     8221 tgttgcattc cagagggcaa cgtggcgttt ttcgctgctc ccgcctgacg cgccagggaa
     8281 aggcatagcg ggcgtttttc tgtttgcagc gtcgccgtta gcgcatttcc ccagtgggat
     8341 ttgcgcacgc ttacggttgg aatatctaac gaagtcacct ggcagatgct tgcaccatgt
     8401 aaacgccagg ccagccgggt cgacagttca tcgccaaacg ttcccggcgg aaagagaaca
     8461 acgtccgcag gcgttcgctg ccactgttcc accaacgcat ccagcacctg ttccgccact
     8521 acaggctgag gttcaatctg ccagtgcgcc agggtacaac cgctgaaatc ctgcgccgcc
     8581 agccagcttg ctattgcggc attctcctga tttattgtca caattgcgat attcatggct
     8641 gcatcctttg gcgtaaatag tcctgccata gcttttgagc tttttctgct accgtttgcc
     8701 catcaatcag cgtcgctccg cgtcgttgct ctgctcttgc cagttgcaga cactgcatcg
     8761 ctggcatttc ggcagcaaca gttttacgga taatttctgc tttccccgca gccattcgct
     8821 ggcgcattcc cggtactggc aaggccactt caccgcactg acgcacggca atcaccgcag
     8881 gcaagcgaac ccggcaacaa cgcaacccat gttcagtacg ctgttcgagg gtgataaaca
     8941 gcgcgtcgag agtgaaacgc tccacctggg tgaagcaggg ccagcccagc atttccgcca
     9001 gcaaaaatgg cgtttgccca ttctgccctt cgctgctttg gcagccggta attatcagat
     9061 ccagcggatt ctgatgctgc cattcggcaa tatggcgagc gacaaattcc ggcgcaaagc
     9121 gcagatctgc cgccgtctcc agcaatacag cttcctcaaa cccaagagcc atgagatagc
     9181 gcagccagtg caatgcccgt tcatccccca tgctcaacgc ggttaaagac atcggcgtac
     9241 cgttttttct ctgcgccaac agcagcgcgg cagcggcctg ttcatcagca ccgagtaaac
     9301 ttcgcagtag cgaaatatcc ggtccgcttt taccctgagc cgccgcctgc cactcttttt
     9361 ccgccagcat tccggcatcc ggttcggctt taaacgctaa cagaatgttc attcgcacct
     9421 cctacatttc ccgccgccac cagcgggagg gctttagttt ctggtgccca tagccaggtc
     9481 acaacaaaac caaccaacaa cactgtcgcc aggagcaata aggtgacttg cattccccac
     9541 tgcgccagca cccacggcag caggccagta cttaccgccg cgccaagtcg actcatggca
     9601 gtggcaaaac cgacgcccag cgagcgaatg tcagtaggaa aactttccgc aggcaaaatg
     9661 cccaccagat tactgactgc cgaaatggtg gtgctgaaga gaacaaaaag cagcagcgtt
     9721 aatgaactgc cggaaggcaa acaggccatg actaccagcg ttgccgccag cagcaaaaaa
     9781 cttcccagca aaaatttgcg atgtgccagc aggtgcgtca gaactaatcc cagcagcgcg
     9841 cccacaatta acaacgcatt aagcatcagg ctggcagtca gcgcatcttc cagaccaata
     9901 gtctgggcga tagttggcag ccaggtataa atcacaaacc atgggattac gaggcagaca
     9961 aagaagacgc tgttaaacgc cgtgcgccgc cagtaacgcg aagagaacaa ggttttgatg
    10021 tgtttatggg tcgccgttac cacttcatcg cccagtaaaa catggggacc aaaatagcga
    10081 tgcacgatag cgtgagcttc tgcaaaacgc ccctggcgca gtagccagcg cggtgattct
    10141 ggcgttcccc agcgtaataa cgtaatcaac aacgcgggca gagctgccga tgccagtagc
    10201 cagcgccagg cctccgggtt ttcggaaata aagtgatgtc cggcaatact tgccagcaca
    10261 tagcctactg tccacaccac gctgaatgcg cccagcaaaa taccgcgatg gcggcgcggg
    10321 gaaaattcag ccagcaaggt gtgacctact gaataatcgc ctcccagacc aatgccaatc
    10381 aaaatgcgca gtccaataag atgctctggc gtggtggcaa aaaattgtaa aaacgaagca
    10441 agcgtaatca gcaaaaagct gaaggtgaag attttttgcc gaccaatatg gtcggagatc
    10501 cacccaagaa ccaggctgcc aaggaacaaa ccaaggagcg ccgagccgcc gatcattccc
    10561 gccataaacg gcgtcagttg catggcgggc gtaagctgaa taatggcgta accaatgacg
    10621 ccgagaacat aaccgtcggt caggtgtgcg ccgaaagtga gcgcagcaat gcggcagtga
    10681 aaacggttaa gcggtaaatc atccattcgc accggtgaag tgttcatctt taccccttca
    10741 ttgtccggta ataagaacgg cttctcgcct gagaagccga aaaggcaacg ccccgtcatc
    10801 gcggaacgct gcctgacaca ttatttttca atcggataga tagtacccgt attcataatg
    10861 ccattaggat cgaactgctt tttcagccct tccagcaacg cccacgcgct gccgtgttcc
    10921 agtttgctcc agtgaacgcg atgtttaccg ataccgtggt ggtgcaccat cgaaccgccg
    10981 aggcgaatgg tttcttcaca gatgatcttg ttgagcggat tgtggtactt gtcgatttcc
    11041 tcttccggct tacagtcaac gacgttgtaa tcgtagacga agtacatgtt ggtgccgttc
    11101 tgatagctat gagaggaatg accgcccagc atggtgatgt cgtcggcgtg cgggaactca
    11161 gtacgaatac ggttaataac gctttcgtag atttcgtgga tgcagctcca gcagccggat
    11221 acttcggtgg taaagcccat gttgccggtt ttgaggatct gcacacgttc ggcagccact
    11281 ttatccggtc cccagttcag gttgttaaac caggtttcga tcagcttgct gtccacgcgc
    11341 tggcattgcg ggtagcgggc aacgatttcc gcaatccctt cgcccgtcac cttcgcaatg
    11401 cgagggttac cttcagccat aaagatcagc acgcattttc cgtcggcaaa atgggtgaag
    11461 tgttgggtgc catcttcagc gtcatacaaa cgagcgattg acggacgata cccttccacc
    11521 atgatttcac gcaggatgtt gaagccggtt ttcatgtctt ccaggatata gccgtagaag
    11581 aggttgtttt ccggggtgaa tttaaagatt ttcactgtta cttcagtgat atagcacaat
    11641 gcaccttcgt tgccgatgat gatgtgacga atgtccgggc cagccgcgcg gcgtggcacg
    11701 tttttaatgc gtgtgacggt gccatcagcc aatactgctt ccagaccaac gaccatatct
    11761 tcgattgcgc cgtagagtgt ggagaactgc ccgatacttc gggttgctac caggccgccc
    11821 atctgcgcca gcggctttga ctgcggagaa tgccccgtgg tgtaaccttt ttcacgcaac
    11881 gcgttttcca gcacttccag cggaacacca cattgcgccg tcgcctgcat attctcaata
    11941 tcaatattaa tgatttgatt catggcggag ccgtcgagca ccaccgagtt ttctacaaca
    12001 gtttccagcc caccttcggt ggcggaagca ccggtacgcg gcacaccgtt aattttgtgc
    12061 gcattcataa aattcagcac acgggatact tgctctgtgg aaccgagttt tacgaccgct
    12121 gccggaatcg gcaaagtata aatgccatga atatccggaa atttacgaaa acggtcaata
    12181 ctgtttttct ttaatactgt ttcatcggta attacgcgat ctgcaccaac aatttccttt
    12241 agctggtcga caatcgctgc gcgagataaa gacatagtaa ttccttcctg ataataaaaa
    12301 tggaataatc attaataaga gaaaacagaa accaccgtta tgggttagcg cactaaataa
    12361 ccgccatcaa ccactaataa atgcccgttg acataattcg atgccggact tgcgaggaat
    12421 acggctgcgc ccattaaatc ctgagtatcg ccccaacggt ttgccggaat atgatcaaga
    12481 acgcgctgat tggtttctgg attactgcgt gtcgccagcg taatatctgt tgcataatag
    12541 ccaggggcga taccatttac ctgaatatta tattgaccta gttcatcaca ataagctttg
    12601 gtgaacccgg caagagcatg tttagtggca gaatatgcag gtgaccattg tccacctaag
    12661 taagagaaca atgaacagat attaataatt ttgccgcttt tctgcgggat cataattttt
    12721 gcagcttcat agcttaactc gaatgcggcg gtcaggttca catcaatcat cggatcccag
    12781 tcggcacgac cgaagtccag caccttattc agcttacaaa taccggcatt gttaaccaga
    12841 atatcaactg taccgaaacg ctcacagcaa gcagcgataa tcttctgcgg cgcgccttct
    12901 gcggtgatat ccacctgcat gaagtccacc tcaacaccct gtttttcaat catttccttt
    12961 gtttcgccgt tatctttgac gaaactagga ataaagatat ttgcgccagc tttggccaac
    13021 gccatggcaa atgcctggcc taaaccgcta ttcccaccgg taacaattgc ggttttacct
    13081 ttcagggaga aaaaatccat tgagaacgca ttgagagatt cgattgacat agttagctcc
    13141 aatttccgta aggcaaaaaa aaagaaaggt aacttccccc gcgagaggga agttaccttt
    13201 ctcattatct ctggtaactg gagataattt ttagcataag ggcataactg ctaatgtgat
    13261 cgtaatcaca gtgtgatatt cgtattgtca aataatttta aaaagcagaa gcgtgattac
    13321 tctcacacaa cacctctgct ttccatgtta tttattattt caattactag agacctgaga
    13381 aaagtaatcc acctgaaagg gcggcttact tttctctttt ttttgtctat tacaaatggg
    13441 aatacgatat gcaacacaac tcatatcgcc gttggataac cctcgcgata attagtttta
    13501 gcggcggcgt tagtttcgac ctggcttatt tacgttatat ttatcaaatt cccatggcga
    13561 aatttatggg attcagcaat accgagatag gtttaataat gagtaccttt ggtattgcgg
    13621 ccattattct ttatgccccc agcggcgtta ttgccgataa attttcacac cgcaaaatga
    13681 ttacttccgc gatgatcatt accggattac tgggtctgtt aatggcaacg tatccaccgc
    13741 tgtgggtaat gctctgtatt cagatcgcct ttgcgataac gacgatttta atgctgtggt
    13801 cggtgtcgat taaagctgca tcgttgcttg gcgatcatag cgagcaaggg aaaattatgg
    13861 gctggatgga agggctgcgc ggcgtcggtg taatgtcgct ggcggtgttt accatgtggg
    13921 tcttttctcg ctttgcaccg gatgacagca ccagcctgaa aacggtcatt atcatctata
    13981 gtgtggttta catcttgttg gggattctgt gctggttttt tgttagcgat aacaacaacc
    14041 tgcgcagtgc caataacgaa gaaaaacagt cattccagct tagcgacatc ctggccgttt
    14101 tgcgtatcag caccacctgg tattgcagca tggtgatttt tggcgtcttc accatctacg
    14161 ccattctgag ttactccacc aactatctga ccgaaatgta tggcatgtcg ctggtggcgg
    14221 cgagctacat ggggattgtg atcaacaaaa tattccgcgc gctgtgcggc ccacttggcg
    14281 gcataatcac cacctacagc aaagtgaaat cccctacccg cgtgatccaa atcctttccg
    14341 tactcggcct gctgacgtta actgccctgc tcgtcacgaa ctctaacccg caatcggtcg
    14401 cgatggggat tggcctgatt ttactgctgg gattcacctg ttacgcctca cgcgggctgt
    14461 actgggcctg ccctggcgaa gcgagaacac cgtcttacat tatgggcacc acggtaggta
    14521 tttgttcggt gattggattc ctgccggatg tcttcgttta cccaattatc ggccactggc
    14581 aagacaccct gcccgctgca gaagcctacc gcaatatgtg gctgatgggc atggcggcgc
    14641 ttggcatggt gattgtcttt acctttttgc tgttccaaaa aattcgtact gctgatagcg
    14701 cccccgcaat ggctagcagc aagtaagcca ggaaaattac aggagaaaaa tcatgtcgaa
    14761 aaaatacatc atagggattg atggcggaag tcagagcaca aaagtggtga tgtacgatct
    14821 ggaaggtaac gtggtttgcg aaggcaaagg cttattacag ccgatgcaca cgccagatgc
    14881 cgatactgca gaacatcctg acgacgattt atgggcatca ttatgttttg ccggtcacga
    14941 tttgatgagt cagtttgccg ggaataaaga agatattgtc ggtattggtc tgggatccat
    15001 ccgttgctgc cgtgcgttat tgaaagccga tggcacgcct gctgcgccgt tgattagctg
    15061 gcaggatgca cgcgttacac gcccttacga acacactaac cctgacgtgg catatgtcac
    15121 ctctttttcg ggttatctga cgcatcgctt aaccggcgag tttaaagaca atatcgccaa
    15181 ctattttggt cagtggccgg tggattataa gagctgggca tggagcgaag atgctgcggt
    15241 aatggataag tttaatatcc cccgtcatat gctgtttgat gtgcaaatgc ctggcaccgt
    15301 cctcggacat atcacaccac aagccgcact ggcgacacat ttcccggcag gactgccggt
    15361 tgtttgtacc accagtgata aaccggtaga agctctgggg gccggattac tggatgatga
    15421 aacggcggta atttctcttg gcacttacat cgcattgatg atgaacggca aagcactgcc
    15481 gaaagatcca gtagcgtact ggccgattat gtcttctatt ccgcaaacat tgctgtatga
    15541 aggttacggt attcgcaaag gcatgtggac ggtgagctgg ctgcgcgaca tgctaggcga
    15601 gtcgttaatt caggatgcca gggcgcagga tctttcaccg gaagatttac tcaacaaaaa
    15661 agcttcttgt gtgccgccag gctgtaatgg tctgatgacg gtgctggact ggctgaccaa
    15721 tccgtgggaa ccgtacaaac gcgggattat gatcggcttt gattccagca tggattacgc
    15781 atggatatat cgttcgatac tggaaagcgt ggcgctgacg ctgaagaaca attacgacaa
    15841 tatgtgtaat gaaatgaatc actttgcgaa gcatgtgatc attactggcg gcggttcgaa
    15901 cagcgatctg tttatgcaga tttttgccga cgtgttcaac cttccggcac gacgtaacgc
    15961 cattaacggt tgtgcaagcc tgggggcagc gattaataca gcggtaggtc tggggctata
    16021 cccggattac gcaacggctg tcgataacat ggttcgcgtg aaagatatct ttataccgat
    16081 tgagagcaat gccaaacgct acgacgcgat gaataaaggc attttcaaag acctaaccaa
    16141 acatactgat gtgatcctga aaaaatcgta tgaagtgatg catggggaat tggggaatgt
    16201 ggattcgatc cagagctggt cgaatgcgta agtgaggaag gccgggcggg aaactgcccg
    16261 gcctgaacat acctgaatgg ttatccccgc tgacgcgggg aacataagtt cgacaactta
    16321 aaaaatgata acaagtccgg tttatccccg ctgatgcagg gaacataata aaaactttaa
    16381 ctagttcggt ttatccctgt ttttacaagg aatattaact acactcgatg tctttagaat
    16441 aaaagacaat acgaatcgca ctttatca
//
LOCUS       DAPHKZ010000098        16335 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.098, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000098 DAPHKZ010000000
VERSION     DAPHKZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16335
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.098"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(105..800)
                     /gene="aqpZ"
                     /locus_tag="RH288_003333"
     CDS             complement(105..800)
                     /gene="aqpZ"
                     /locus_tag="RH288_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HDV4032364.1"
                     /translation="MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFG
                     LTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLI
                     ASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG
                     FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGII
                     GGLIYRTLLEKRD"
     gene            1226..2884
                     /locus_tag="RH288_003334"
     CDS             1226..2884
                     /locus_tag="RH288_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HDV4032365.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTP
                     CTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQA
                     KGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVE
                     HVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRMAQIPENVPMNLRKIISKAI
                     HRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD"
     gene            complement(2881..3837)
                     /locus_tag="RH288_003335"
     CDS             complement(2881..3837)
                     /locus_tag="RH288_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001322270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF535 domain-containing protein"
                     /protein_id="HDV4032366.1"
                     /translation="MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQ
                     KFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEAL
                     RYHYALLRECMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILF
                     RNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVM
                     EAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHY
                     RLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG"
     gene            3988..5103
                     /gene="macA"
                     /locus_tag="RH288_003336"
     CDS             3988..5103
                     /gene="macA"
                     /locus_tag="RH288_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415399.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HDV4032367.1"
                     /translation="MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPG
                     DLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIK
                     EVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTKAVSQQDLDTAATEMAVKQAQI
                     GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA
                     DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYY
                     ARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETR
                     EREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ"
     gene            5100..7046
                     /gene="macB"
                     /locus_tag="RH288_003337"
     CDS             5100..7046
                     /gene="macB"
                     /locus_tag="RH288_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HDV4032368.1"
                     /translation="MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASG
                     SGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLT
                     AEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD
                     GEIVRNPPAIEKVNVTGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDIYPGKDFGDDDPQYQQALKYD
                     DLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQ
                     EQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVL
                     RVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMD
                     GVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(7119..7343)
                     /gene="cspD"
                     /locus_tag="RH288_003338"
     CDS             complement(7119..7343)
                     /gene="cspD"
                     /locus_tag="RH288_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HDV4032369.1"
                     /translation="MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVQFDVHQGPKGNHASVIVPVEVEAAVA"
     gene            7666..7986
                     /gene="clpS"
                     /locus_tag="RH288_003339"
     CDS             7666..7986
                     /gene="clpS"
                     /locus_tag="RH288_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HDV4032370.1"
                     /translation="MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            8017..10293
                     /gene="clpA"
                     /locus_tag="RH288_003340"
     CDS             8017..10293
                     /gene="clpA"
                     /locus_tag="RH288_003340"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HDV4032371.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
                     SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ELTYGFQSAQKHKAEAAH"
     gene            complement(10637..10724)
                     /locus_tag="RH288_003341"
     tRNA            complement(10637..10724)
                     /locus_tag="RH288_003341"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10688..10690),aa:Ser,seq:gga)
     gene            10958..11896
                     /gene="ghrA"
                     /locus_tag="RH288_003342"
     CDS             10958..11896
                     /gene="ghrA"
                     /locus_tag="RH288_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415551.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HDV4032372.1"
                     /translation="MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALV
                     WHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEVLNPSVPLFRLEDTGMGEQMQEY
                     AVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRF
                     PLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPD
                     GAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHV
                     AAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY"
     gene            11951..12688
                     /gene="ycdX"
                     /locus_tag="RH288_003343"
     CDS             11951..12688
                     /gene="ycdX"
                     /locus_tag="RH288_003343"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding phosphatase"
                     /protein_id="HDV4032373.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNS
                     SFLHSRKGSEDNCREVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPER
                     ILNVSPRRLLNFLESRGMAPIAEFADL"
     gene            12712..13266
                     /gene="ycdY"
                     /locus_tag="RH288_003344"
     CDS             12712..13266
                     /gene="ycdY"
                     /locus_tag="RH288_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone YcdY"
                     /protein_id="HDV4032374.1"
                     /translation="MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DELLTRLQKSCDMTQVSADYNALFIGDECAVPPYRSAWVEGATEAEVRAFLSERGMPL
                     ADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
                     RTMAPLTRDAISAMWDELEEDSEE"
     gene            13368..13859
                     /locus_tag="RH288_003345"
     CDS             13368..13859
                     /locus_tag="RH288_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415554.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDV4032375.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGLKGLAISAATLLSGVVWAMVIIYGSALAPHLEILGYVITGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWKLVLPSLALGLIFGYAMKNSGLWLAARSAKTAHREQEIK
                     NKA"
     gene            complement(13923..14756)
                     /gene="csgG"
                     /locus_tag="RH288_003346"
     CDS             complement(13923..14756)
                     /gene="csgG"
                     /locus_tag="RH288_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HDV4032376.1"
                     /translation="MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     VGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKAERQNDILVKYRHMSVPPE
                     S"
     gene            complement(14783..15199)
                     /gene="csgF"
                     /locus_tag="RH288_003347"
     CDS             complement(14783..15199)
                     /gene="csgF"
                     /locus_tag="RH288_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HDV4032377.1"
                     /translation="MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNS
                     AQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIV
                     DIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF"
     gene            complement(15224..15613)
                     /gene="csgE"
                     /locus_tag="RH288_003348"
     CDS             complement(15224..15613)
                     /gene="csgE"
                     /locus_tag="RH288_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HDV4032378.1"
                     /translation="MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFY
                     RAFSDKWESDYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPLKRDFEKTVVFAL
                     IQTEEALNRRQINQALLSTGDLAHDEF"
     gene            complement(15618..16268)
                     /gene="csgD"
                     /locus_tag="RH288_003349"
     CDS             complement(15618..16268)
                     /gene="csgD"
                     /locus_tag="RH288_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HDV4032379.1"
                     /translation="MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQ
                     RSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWP
                     HINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR"
BASE COUNT         4094 a         3830 c         4316 g         4095 t
ORIGIN      
        1 caatatgttg cttagctcat gaaaggagcg caacaagatg atgaatcaac atataacaac
       61 atcttaaaaa aaggcctgac attacgccag gccttctgcg ttaattaatc acgcttttcc
      121 agcagggtcc ggtaaatcag accaccgata atgccgccga caattggcac cacccagaag
      181 aaccacagtt gttctaatgc ccagccgccc tggaagatag caaccgcggt gctgcgcgcc
      241 gggttaacag aagtgttagt caccggaata ctaattaagt gaatcagggt taaggccaga
      301 ccaatagcga tcggcgcaaa acctgccggc gcgaatttgt cggttgcgcc gtggatcacc
      361 aacaggaaac ctgcactcaa taccagttca actaccagcg cggaaagcat ggaataaccg
      421 cctggtgaat gctcgccata accgttagaa gcaaaaccgc tggctgccgc gtcaaaaccc
      481 gttttaccac tggcaattaa atacagcagc gccgctgcaa caataccgcc gacaacctgg
      541 gcaattacgt agccaacgac ttcttttgcc ggaaaacgtc cgccagccca taaaccaata
      601 gtgaccgccg ggttaaaatg accaccagaa atatgaccaa cagcaaaggc catcgtcaga
      661 acggtcagac cgaacgccaa cgccacgccg gcaaaaccaa tgcctaattc cgggaagcct
      721 gcggccagta cagcactacc acagccacca aaaacaagcc agaaagtacc aaaacattca
      781 gctgctaatt ttctgaacat atccacctca attaaaaatt gaccctgtga aaaatatggt
      841 cgttttatag ggtcgtcgta aaaaagtgac gacggaaata atgcgcggct attttaaaaa
      901 cgaaggcgag tcattcacca gataaataaa tccagtaaat ttgatttagg gcaacagcgg
      961 gttgccccat atagtcattt gtctgattga cagtgtagtg cacgcaaaag atttaatcct
     1021 ttaggcgtaa taaaaaataa tttatcatgc taattatttg attttgttgt ttttgcagac
     1081 ttatcagcaa gagggagtat aacgcgatta ttcgctcatt tttcagacat ttgccatgct
     1141 taaatgtgat gtcatcacgt attagcaagg cctttcccgt tatactgcca gcgtaaagga
     1201 taagtcacat atttctggag gggatatgat tcttgagcgc gttgaaattg tgggttttcg
     1261 cggtatcaac cgtttgtcgt tgatgctgga acaaaacaac gtcctgattg gggagaacgc
     1321 gtggggtaaa tccagcttgc tggacgcctt aactctgctg ctatcgccag aatcagatct
     1381 ctaccatttt gagcgcgacg atttctggtt cccgccggga gatatcaacg ggcgagaaca
     1441 tcatctgcat attattttga ccttccgcga atcgctgcca ggccgacatc gggttcgccg
     1501 ttatcggccg ctggaagcgt gctggacgcc atgcaccgat ggctatcacc gtatttttta
     1561 tcgtctggaa ggggagagtg cggaagacgg cagcgtgatg acactgcgca gttttctcga
     1621 taaagacgga catccgattg atgtcgagga tattaacgat caggcacgcc atctggtgcg
     1681 tttaatgccg gtgctgcgct tgcgtgatgc ccgttttatg cgccgtattc gtaacggcac
     1741 ggtgccaaat gtccctaatg tggaagtcac cgcgcgccag ctcgatttcc tcgcccgtga
     1801 gttatcctca catccgcaaa atctctctga tgggcagatt cgtcagggac tttccgcaat
     1861 ggtacagctg cttgagcatt atttctctga gcagggggcc ggacaggcgc gatatcgttt
     1921 aatgcggcgg cgagccagca atgagcaacg aagctggcgc tatctggata tcatcaaccg
     1981 gatgattgac cgacctggtg ggcgctcgta tcgggttatt ttgctcggcc tatttgctac
     2041 tttgttgcag gcaaaaggca cattgcgact ggataaagac gcccgtccat tgttgctgat
     2101 cgaagatcca gaaacccgtt tacaccccat tatgctttca gttgcctggc atctgttgaa
     2161 tcttctgcca ttgcagcgca ttgccaccac caactcgggt gagttgcttt cgttaacgcc
     2221 ggtagagcat gtttgccgac tggtacgtga gtcctcgcgc gttgccgcct ggcgtctggg
     2281 gccgagtggc ttgagtaccg aagatagccg acgcatatcc tttcacattc gttttaaccg
     2341 tccgtcatcg ctgtttgcac gctgctggtt gctggtggaa ggggaaacgg aaacctgggt
     2401 tatcaatgaa ctggcgcgtc agtgcggaca tcattttgat gccgaaggga tcaaggtcat
     2461 tgagtttgcc cagtccgggc taaagccact ggttaaattt gcccgccgaa tggggattga
     2521 atggcatgta ctggtcgatg gcgatgaagc agggaagaaa tatgccgcta cggtacgcag
     2581 cctgttgaat aacgatcggg aagccgaacg agaacattta acggcgttac cggcgctgga
     2641 tatggaacat tttatgtatc gccagggatt ttccgatgtg ttccaccgca tggcgcaaat
     2701 cccggaaaat gtaccgatga atctacgcaa aattatctcg aaagcgatcc atcgctcttc
     2761 caaacccgat cttgccattg aagtggcaat ggaggcagga cgtcgtggtg tggactccgt
     2821 accgacgctg ctgaaaaaaa tgttctcacg cgtgctgtgg ctggcgcgcg gtcgcgcgga
     2881 ttaaccgcga aacatcgtgg ccatttgtgg ctgaatagcg tcgagcatct catagcgccg
     2941 acggtattca gcccgttttt tactggcgat ttcggcaatc tcttttcgtg ctatctgtgc
     3001 tggaaggcgg taatggcgtt cagcatcaca tacgccgcca accgattccc agaaagcgtt
     3061 gtaatcagcg tggatcttgc cttctttatc gcgataacgc aggctgcggt aaatatgcgt
     3121 ttcattgctg acggcaataa tctgctctac ctgcaaacgt tgggcaaaca gacaggccgc
     3181 ttccatcacg aggcgtttgg gaaatagccc gtggcaggct ttcgtcgcat tctggatttc
     3241 ctgatgtgga atttcccatt ttgcgccttg cagtccgcca ataaacatcg ttcttttccc
     3301 ctgatattca cacagggtaa acgtgatctc tgccagagga ataccttcgc tgttgcggaa
     3361 caggattgtg ctgtcacctt ctttatccat tgagatcatc atggtcagct caagcgtgaa
     3421 ctgctcgccg tttttgcctt ccagcttcgc cagttgcagc ccgggggtat tcaaatataa
     3481 gctgaattct tccgccgaca tacattcgcg gagtaacgca taatggtaac gtaacgcctc
     3541 cagcaattgc ttacggctaa gattcgccgc aaggtaaggg cgatgcagac gcacaggcag
     3601 tcgcggctgg cgcgttaaca atacattgag attaggccag tgggaaagtt cgttcatcca
     3661 ctcaacgctt aaacgcggca taatcaacga gcgcagcaaa aatttctggc gaaaactacg
     3721 gcgatgccag aatttacccg gccgacactg tccacgtgcc agactaagaa aaagtgacag
     3781 gctgctgaga gattcagatg gcgtaaaggt ccgttcagtt agctgcgaca tattcatgaa
     3841 atcaatggtt atacatggcg tcgatttcac cattgcgtat cttaaccaaa catcaatagt
     3901 gtgattacta acgtaaattt tagggttttg ttgatatttc gttgaagtta atgacccgga
     3961 ttggcatatg gagtattcag aaaatttatg aaaaagcgga aaaccgtgaa gaagcgttac
     4021 gttattgcgc tggtgatagt catcgccgga ctgattacgt tatggagaat tcttaacgca
     4081 cccgtgccga cttatcagac gctgattgtg cgccccggtg atttacagca aagcgtgctg
     4141 gcgaccggaa agctggacgc gctgcgtaag gttgatgtgg gcgcgcaggt cagcggtcag
     4201 ttgaaaactc tgtcggtggc gattggcgat aaagtaaaaa aagaccagct tttaggggtt
     4261 attgatcctg aacaggctga aaaccagatt aaggaggtcg aagcaacgct gatggagcta
     4321 cgtgcgcagc ggcagcaggc ggaagcggag ctgaaactgg cgcgggtgac gtattcccgt
     4381 cagcaacgtc tggcacaaac gaaggctgtt tcacagcagg atctcgacac cgccgcgacg
     4441 gagatggctg tgaaacaggc gcaaattggc accattgacg cgcaaatcaa gcgcaatcag
     4501 gcttctctcg atacggctaa aaccaatctc gattacactc gcatcgttgc cccgatggcc
     4561 ggggaagtca cgcaaatcac cactctgcaa ggccagacgg tgattgccgc acaacaagca
     4621 ccgaacattc tgacgctggc agatatgagc accatgctgg taaaagcgca ggtttctgaa
     4681 gcggatgtaa tccacctgaa gccggggcaa aaagcctggt ttacggtgct tggcgatcca
     4741 ctgacgcgct acgaggggca aatcaaggat gtactaccga cgccggaaaa ggttaacgac
     4801 gctattttct attacgcccg ttttgaagtc cccaacccca atggtttgct gcggctggat
     4861 atgactgcgc aagtgcatat tcagctcacc gatgtgaaaa atgtgctgac gatccctctg
     4921 tcggcgttag gcgatccggt tggcgataat cgttataaag tcaaattgtt gcgtaatggt
     4981 gaaacacgcg agcgtgaagt gacgattggc gcacgtaacg ataccgatgt tgagattgtc
     5041 aaagggcttg aagcgggcga tgaagtggtg attggtgagg ccaaaccagg agctgcacaa
     5101 tgacgccttt gctcgaatta aaggatattc gtcgcagcta tcctgccggt gatgagcagg
     5161 ttgaggtgct gaagggcatc agcctcgata tttatgcggg tgagatggtc gcgattgttg
     5221 gcgcttcggg ttccggtaaa tcgaccctga tgaatattct cggctgtctg gataaggcca
     5281 ccagcggcac ctatcgcgtc gccggtcagg atgttgccac gctggacgcc gatgcgctgg
     5341 cgcaactgcg ccgcgagcat ttcggcttta ttttccagcg ttaccatttg ctttcgcatt
     5401 taaccgccga gcagaacgtt gaagtacccg ccgtctatgc tggtcttgag cggaaacagc
     5461 gactgcttcg tgcccaggag ttgctgcaac ggctggggct ggaagaccgt acagagtatt
     5521 atccggcaca gctttcgggt ggtcagcaac agcgcgtcag catcgcgcgg gcattgatga
     5581 acggtggtca ggtaattctt gccgatgaac caaccggcgc actggacagc cattctggcg
     5641 aagaggtgat ggcgatcctg catcagctgc gcgatcgtgg gcatacggtg attatcgtca
     5701 cccacgatcc gcaggtcgct gctcaggccg agcgggtgat cgaaattcgc gacggcgaaa
     5761 ttgtgcgcaa tcctcccgcc attgaaaaag tgaatgttac tggcgggacg gaacctgttg
     5821 tcaacacggt gtctggctgg cggcagtttg tcagcggttt taacgaggcg ctgacgatgg
     5881 catggcgggc gctggcagcg aataaaatgc gtactttact gaccatgctg gggattatta
     5941 tcggtattgc gtcggtggtt tccattgtcg tggtgggtga cgccgccaaa caaatggtgc
     6001 tggcggatat tcgttctatt ggtacgaata ctattgatat ctatcccggg aaagattttg
     6061 gcgatgacga tccgcaatat cagcaggcgc tgaagtacga cgacttaatc gccatccaaa
     6121 aacaaccgtg ggtcgcctca gccacacctg ccgtctcgca aaacctgcgc ctgcgttata
     6181 acaatgttga tgttgctgcc agtgccaatg gcgtgagcgg cgattatttt aatgtctatg
     6241 gcatgacctt cagtgaagga aacaccttta atcaggagca gctgaacggt cgtgcgcagg
     6301 tcgtggttct cgacagtaat actcgccgcc agcttttccc ccataaagca gatgtggttg
     6361 gcgaggtgat tctggtcggc aatatgcccg ccagagtcat tggtgtggcg gaagaaaaac
     6421 agtcgatgtt tggtagcagt aaagtgctgc gtgtctggct accttacagc acgatgtccg
     6481 ggcgagttat gggccagtcg tggcttaact ccattactgt cagggtgaaa gaaggatttg
     6541 acagcgccga ggcggaacag caactcacgc gtttactttc actgcgccac ggaaagaagg
     6601 atttctttac ctggaacatg gacggcgtct tgaaaactgt tgaaaagacc acacgtactt
     6661 tacaactgtt tctgacgctg gtggcggtga tttcgctggt ggtgggcggt attggtgtaa
     6721 tgaatattat gctggtgtca gtgaccgagc ggacgcggga aattggcatt cgcatggctg
     6781 taggtgcgcg agcaagcgat gttttgcaac agttcctgat cgaagccgta ctggtttgcc
     6841 tggtcggtgg cgcgttggga ataacactgt cactgttaat tgctttcacc ttgcagcttt
     6901 tcttacccgg ctgggagatt ggtttttcac cgttggcgct gctgctggcg tttctctgct
     6961 cgacggtcac cgggatttta tttggctggt tacccgcacg aaatgcggca cgactggatc
     7021 cagtagatgc tctggcacga gagtaatttt tgagataaaa atgccagccg atcgggctgg
     7081 cattttgcct ttaggatgta cacaatgaga cagaagagct atgcgactgc cgcttctact
     7141 tcgacgggca caataacact ggcgtgattg ccttttggcc cctggtggac atcaaactga
     7201 acggattgtc cagcttttag cgttctgtaa ccatccatct gaatggtgga ataatgagcg
     7261 aaaatatctt cgccgccgcc ttcagggcag atgaaaccaa accctttggc attgttgaac
     7321 cacttaacag tacccttttc catgcttcga catccttcgc aaatcttata caagtaagat
     7381 ggaataaacc ggggtcagag agggggctgt tcaaaacctc gccaactcta gaaatacaat
     7441 ttagagaatt agggcgagcc gtcaagcatt tgacagggga caaggggcag gtatgaatca
     7501 aaaatttgaa gcagttaacg ctattgacag gaatgtgaca gatgtcgctg atgccaacga
     7561 tagatgatag ttatctatca tgtggagtag attggtcagg caaataagct cttgtcagcg
     7621 gcagggcgtt ctgccgataa ccgtaaccga agatgataac tgacaatggg taaaacgaac
     7681 gactggctgg actttgatca actggcggaa gaaaaagttc gcgacgcgct aaaaccgcca
     7741 tctatgtata aagtgatatt agtcaatgat gattacactc cgatggagtt tgttattgac
     7801 gtgttacaaa aattcttttc ttatgatgta gaacgtgcaa cgcaattgat gctcgctgtt
     7861 cactaccagg ggaaggccat ttgcggagtc tttaccgccg aggttgcaga aaccaaagtg
     7921 gcgatggtga acaagtacgc gagggagaat gagcatccat tgctgtgtac gctagaaaaa
     7981 gcctgaatgc aggcataaaa attgggggag gtgcctatgc tcaatcaaga actggaactc
     8041 agtttaaata tggctttcgc cagagcgcgc gagcaccgtc atgagtttat gaccgtcgag
     8101 cacttgttac tggcgctgct cagtaaccca tctgcccggg aggcgctgga agcgtgttct
     8161 gtggatttgg ttgcgctccg tcaggaactg gaagccttta ttgaacaaac cacacccgtt
     8221 ctgcctgcca gtgaagagga gcgcgacaca cagccgacgc tgagttttca gcgtgtactg
     8281 caacgtgcgg tcttccatgt ccagtcctcc ggtcgcaatg aggttaccgg tgcaaacgtt
     8341 ctggtcgcta tctttagcga acaggagtcg caggcggcat atctgttgcg taaacatgaa
     8401 gtcagccgtc tcgatgtggt gaactttatc tctcatggca cgcgtaaaga cgagccgaca
     8461 cagtcttctg atcctggcag ccagccaaac agcgaagaac aagctggtgg ggaggaacgt
     8521 atggagaatt tcacgacgaa cctgaatcag cttgcgcgcg tgggtggaat cgacccactg
     8581 attggtcgtg agaaggagct ggagcgtgct attcaggttc tctgccgtcg ccgtaaaaac
     8641 aacccgctgc tggtggggga atctggtgtc ggtaaaaccg cgattgcgga aggtcttgcc
     8701 tggcgaattg ttcagggcga tgtgccggaa gtgatggctg actgtacgat ttactctctc
     8761 gatatcggtt ctctgttagc gggcacaaaa tatcgcggcg actttgaaaa acgttttaaa
     8821 gcgttgctca agcagctgga gcaggacact aacagcatcc tgtttattga tgagatccac
     8881 accattatcg gtgcgggtgc agcgtctggt ggtcaggtcg atgcggctaa cctaatcaaa
     8941 ccgttgctct ccagcggtaa aattcgtgta attggttcga caacctatca ggagttcagc
     9001 aacattttcg agaaagaccg tgctctggcg cgtcgcttcc agaaaattga tattactgaa
     9061 ccgtcgatcg aagaaactgt tcaaatcatc aatggcctga aaccgaagta tgaagcgcac
     9121 cacgacgtgc gttataccgc aaaagcggtg cgtgcggcgg tagagctggc ggtgaaatac
     9181 attaacgatc gtcatctgcc ggataaagcc attgatgtta tcgacgaagc gggcgctcgc
     9241 gcacgcctga tgccggtaag caaacgcaag aaaaccgtta atgtggcgga tattgagtcc
     9301 gtggtggccc gtattgcacg cattccagag aagagtgttt ctcagagtga tcgtgatacc
     9361 ctgaaaaacc tcggcgatcg cttgaaaatg ctggtcttcg gtcaggataa agccattgag
     9421 gcgctgactg aagccattaa gatggcgcgt gcaggtttag gtcacgaaca taaaccggtt
     9481 ggttcgttcc tgtttgccgg ccctaccggg gtcgggaaaa cagaggtgac ggtacagctt
     9541 tcgaaagctt tgggcattga gcttctgcgc tttgatatgt ccgagtatat ggaacgccat
     9601 accgtcagcc gtcttattgg tgcgcctccg ggatacgttg gttttgatca gggcggtttg
     9661 ctgactgatg cggtcatcaa gcatccacat gcggtgctgc tgctggacga aatcgagaaa
     9721 gcgcacccgg acgtgttcaa tattctgttg caggtgatgg ataacggtac gctgaccgat
     9781 aacaacggac gcaaagcaga cttccgtaac gtggtgctgg tgatgaccac caacgccggg
     9841 gtacgggaaa ctgagcgcaa atccattggt cttatccacc aggataacag caccgatgcg
     9901 atggaagaga tcaagaagat ctttacaccg gaattccgta accgtctcga caacattatc
     9961 tggtttgatc atctgtcaac cgacgtgatc catcaggtgg tggataaatt catcgtcgag
    10021 ttgcaggttc agctggatca gaaaggtgtt tctctggaag tgagccagga agcgcgtaac
    10081 tggctggccg agaaaggtta cgaccgggca atgggcgctc gtccgatggc gcgtgtcatc
    10141 caggacaacc tgaaaaaacc gctcgccaac gaactgctgt ttggttcgct ggtggacggc
    10201 ggtcaggtca ccgtcgcgct ggataaagag aaaaatgagc tgacttacgg attccagagt
    10261 gcacaaaagc acaaggcgga agcagcgcat taatctgatt gttaggtagg ttggtcaagt
    10321 ccgtaatctc gaaagaggtt acggactttt tgtttatggg gtggaggagg ttcagaccct
    10381 ttttttaatg atgatggtaa gttgttgata attagtgctg cgggaaggta aggataaaaa
    10441 agggtgctgc aggagaatgg gatggttttg ctttattaac aacgggctaa acgtgtagta
    10501 tttgagttca ctgccgtaca ggcagcttag aaattcacag gtaacatact ccacccgccc
    10561 accatgttca ctgccgtaca gacagataaa atgcgaaaaa aaagctcgca ctttcgtacg
    10621 agctcttctt taaatatggc ggtgaggggg ggattcgaac ccccgatacg ttgccgtata
    10681 cacactttcc aggcgtgctc cttcagccac tcggacacct caccaaattg tcgttcctgt
    10741 cttgctggaa cgggcgctaa tttagggaaa tcatgacctg aggtcaacaa actttttgaa
    10801 aaaatcgcgc gtttattcaa acttcaatca atgtgtggtt ttaataagcg aaatctgctt
    10861 tttttgccac cgaccacgga tttgttatgc tggtggcctt tgtagatcat aacgataagt
    10921 gcgaataaat ttcgcacaac gcttttcggg agtcagtatg gatatcatct tttatcaccc
    10981 aacgttcgat acccaatggt ggattgaggc actgcgcaaa gctattcctc aggcaagagt
    11041 cagagcatgg aaaagcggag ataatgactc tgctgattat gctttagtct ggcatcctcc
    11101 tgttgaaatg ctggcagggc gcgatcttaa agcggtgttc gcactcgggg ccggtgttga
    11161 ttctattttg agcaagctac aggcacaccc tgaagtgctg aacccttctg ttccactttt
    11221 tcgcctggaa gataccggta tgggcgagca aatgcaggaa tatgctgtca gtcaggtgct
    11281 gcattggttt cgacgttttg acgattatcg catccagcaa aatagttcgc attggcaacc
    11341 gctgcctgaa tatcatcggg aagattttac catcggcatt ttgggcgcag gcgtactggg
    11401 cagtaaagtt gctcagagtc tgcaaacctg gcgctttccg ctgcgttgct ggagtcgaac
    11461 ccgtaaatcg tggcctggcg tgcaaagctt tgccggacgg gaagaactgt ctgcatttct
    11521 gagccaatgt cgggtattga ttaatttgtt accgaatacc cctgaaaccg tcggcattat
    11581 taatcaacaa ttactcgaaa aattaccgga tggcgcgtat ctcctcaacc tggcgcgtgg
    11641 tgttcatgtt gtggaagatg acctgctcgc ggcgctggat agcggcaaag ttaaaggcgc
    11701 aatgttggat gtttttaatc gtgaaccctt accgcctgaa agtccgctct ggcaacatcc
    11761 acgcgtgacg ataacaccac atgtcgccgc gattacccgt cccgctgaag ctgtggagta
    11821 catttctcgc accattgccc agctcgaaaa aggggagagg gtctgcgggc aagtcgaccg
    11881 cgcacgcggc tactaataaa gcatcaggat tcctgctatc cttggcggga attgaataca
    11941 ggagagagtt atgtatcccg tcgaccttca tatgcatacc gttgccagca cacatgcata
    12001 tagcacatta agtgattaca ttgcccaggc caaacaaaag ggcattaaac tttttgcgat
    12061 caccgatcat ggcccggata tggaagatgc gccgcatcac tggcacttca ttaacatgcg
    12121 tatctggccg cgagtggttg atggggtagg gatcctgcgc ggcatcgaag ctaacattaa
    12181 aaatgttgat ggtgaaattg actgcagcgg taaaatgttt gactcgctgg atctaattat
    12241 tgccggtttt catgagccgg tttttgcgcc acatgacaaa gcgaccaata cacaagcgat
    12301 gatcgccact atcgccagcg gcaatgtgca tataataagc catcccggaa atcccaaata
    12361 tgaaatagat gtgaaagccg ttgctgaagc agccgcgaaa catcaggtgg cgctggaaat
    12421 caataattcc tcatttttac actcacgtaa gggcagtgaa gacaactgtc gtgaggtagc
    12481 cgcagcggta cgtgatgctg gaggttgggt ggcattaggc tcggattctc acaccgcgtt
    12541 taccatgggg gaatttgaag agtgtcttaa aatcctcgac gcggtagatt ttccgccaga
    12601 gcgcattttg aatgtttctc cgcgccgctt actgaacttc cttgaatctc gcggtatggc
    12661 accgattgcg gaatttgcag acctttaatt actagtaatg gaaatatatt aatgaacgag
    12721 ttttctatcc tctgtcgtgt gctgggttcg ctctattacc gccaaccaca agatccttta
    12781 ctggtgccgc tgtttaccct gattcgtgag gggaaactgg ctgcgaactg gccactggag
    12841 caggatgagt tgctgacacg tttgcagaaa agctgtgata tgacgcaagt ctctgccgat
    12901 tacaatgcgt tgtttatcgg cgatgaatgt gctgtgccgc catatcgtag cgcatgggtt
    12961 gagggcgcga cggaagcgga agtgcgcgct tttctttctg agcgagggat gccattagcg
    13021 gatacgccag ccgatcacat cggcacattg ctgctcgcag cttcctggct ggaagatcag
    13081 tcaacggaag atgagagcga agcactggaa acactgttca gtgagtatct gttaccctgg
    13141 tgtggtgcgt tccttggcaa agtggaggcc catgcaacca cgcctttctg gcgcaccatg
    13201 gcaccgctaa cccgcgatgc cattagtgca atgtgggacg agctggaaga agattctgaa
    13261 gaataagtgt gatctacgtc actcataact gcaacggata atttgttgtt gcataaaatg
    13321 tgtgctcgat ctcattcatg gccgcgtttt ctgctatcat gcgcggcatg aacatacttc
    13381 tctctattgc aatcacaaca ggcattctct ccggtatctg gggatgggtg gctgtttccc
    13441 tgggcttact aagctgggcg ggcttcctgg gctgtacggc ctactttgcc tgcccgcaag
    13501 gtgggctgaa agggctggcg atctccgctg caaccctgct tagtggcgtg gtgtgggcga
    13561 tggtcattat ttacggtagt gcactggcac cacatctgga aattctcggt tatgtcataa
    13621 ccggtattgt cgcgtttctg atgtgtattc aggccaaaca gctgctgctt tcatttgttc
    13681 cggggacgtt tataggcgca tgcgcgacgt ttgccgggca gggtgactgg aaactggtgt
    13741 taccttcgct ggcgcttggg ctgatatttg gttacgcaat gaaaaacagt ggcctgtggc
    13801 tggcggcgcg tagtgcaaag acggcgcacc gtgagcagga aatcaaaaat aaagcgtgag
    13861 gggcactcac gctttcgctt aaacagtaaa atgccggatg ataattccgg cttttttatc
    13921 tgtcaggatt ccggtggaac cgacatatgg cggtatttca ccagaatgtc attctgccgt
    13981 tctgctttat tttgcaaatc ccacagacca cggtcgatac catcattaat caggaaaatg
    14041 acccctgttt cgatagccga catcaggcac agcataacag gttcgttcga ggtgtaaccc
    14101 acttcccctt caagcaagcg ctggtagtca ataaagcgga aaaccccggc ctgaacttca
    14161 taggaaagta tcgtcttact ggtgttcacc gaagaaagga tctcgccggt actcacattg
    14221 acgacgcgca ggttcacggc aatctgatcg agctggtatt gcgtgtcggc accgatgcca
    14281 aaatatcttg ccccaacccc gccagatttg acgttgcttt cataaccgat aatcgaacct
    14341 tcaaccatga tatttgccgc cgttaaagat tgcagcggga ttcggttatt aatggcaacc
    14401 gtgccgtttt cttgtgccgc acgaataatc ttgcgctcgt taagcaggtt ttgtaagccc
    14461 tggcgctcca gcggtataaa ccagcgagaa tctttcagtg ccgtgaccag cattgccgtg
    14521 gcgctttgcg gaacagcagt ggagaagtta cttgccgggt agggtttaaa ttgcccggtt
    14581 tcgtcctgaa tgttgtatac cgaaacaaag attttacccg tcggcgctgg cagatgggtc
    14641 aaatctttgt agctctgagc acgaggcatt aatgtcggtc tggcggcttc tttaggcggg
    14701 gcggttaagc atccgctcag taacatgacg gcaaccaaaa gaaataagcg ctgcatgatt
    14761 attttcctta tgaagctggg gcttaaaaat cggttgagtt attttgtaaa cccgaaacct
    14821 ggatggtcga ggtttgtccg gttttacgat ctgtcacgtt caactgcaat tgaccatcgc
    14881 ggttggcaat atcgacaata taatcgttgg tcaccatgcg gcccggttta ccggtattaa
    14941 tattcgacag tagcccacct aaaatttgtg actggatggc ctgagtaaag ttatctaacg
    15001 ctgagggtgt ttcaatacca aagtcatcgt tatagctcgg atctttataa gagttttggg
    15061 cctgagcgct atttaataaa aaagcgccat tatttgggtt accaccaaag tttggattac
    15121 ggaactggaa agtcatggtt ccagcccaac ttaatggcga aataagcatg agtagaacta
    15181 ctgcatgttt gacacgcatt gcagcctccg aacaattttt tatttagaat tcatcatgcg
    15241 ccaaatcgcc cgtacttaat aacgcctgat ttatctggcg acgatttagt gcttcttcag
    15301 tttgaatcag tgcaaagacg acagttttct cgaagtctct tttcaacgga aataaaaaag
    15361 tctggaaaat aacgtcctga ttgaccgtta tagtgatcca gcttccccat cgtgcactgg
    15421 gcctttcatt aatcgttaag ttacccgtat agtcactttc ccatttatca ctaaaggctc
    15481 ggtaaaaatc atggccaata gatgaaacag tatggtcagt tagcaatccc gggacttcta
    15541 cctcaacggc gtgaagattc cctgcggcga acagaaattc tgccgccaca atccagcgta
    15601 aataacgttt catggcttta tcgcctgagg ttatcgtttg cccaggaaac cgcttgtgtc
    15661 cggtttttta cggctatctt cttgaaaaga ttataaagat gcgttttaac cgtattttcg
    15721 ctgatgaaca acgaacgagc gatctcgtta ttagacgcgc cgatacgcag cttattcagg
    15781 atctcttttt cccgatgagt aaggagggct gattccgtgc tgttataacg atagttacct
    15841 gaatgcgtaa tcaggtagct ggcaagcttt tgcgtaaagt agcattcgcc gcgcaggacg
    15901 ccttgcaacc cattgacaac acgttcttga tcctccatgg aataaaaaac gccgttgata
    15961 tgaggccagt tttcaatgtc gcggtacggg taatcttcag gcgtatttag caacaatatt
    16021 ttgatattgt tgtttttcct gctcaaagta tcctgccaat aatggataag ctttttatcc
    16081 gcttccatca tatccagaag aataatagag cctgaagaga tatcgtccag agaacgttga
    16141 atattatgta attttcctgt aattgccagc gattgtttaa ggtgctgcaa gagagctgtc
    16201 gcctgcaaag aaggtttagt gatcaacaat aatgtatgac catgaatact atggacttca
    16261 ttaaacatga tgaaaccccg ctttttttat tgatcgcaca cctgacagct gcctctaaaa
    16321 tagaagcacc agaag
//
LOCUS       DAPHKZ010000099        16223 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.099, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000099 DAPHKZ010000000
VERSION     DAPHKZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16223
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.099"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..973
                     /locus_tag="RH288_003350"
     CDS             <1..973
                     /locus_tag="RH288_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013572517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDV4032380.1"
                     /translation="RFLNTEINEIRIFSRDEKKQDDMRKHFKSDKLKFYIGDVRDYQS
                     VSNAMRGVDYIYHAAALKQVPSCEFYPLEAVKTNVLGTENVLEAAITHGVKRVVCLST
                     DKAVYPINAMGISKAMMEKVIVAKSRNLTHTNTTVCCTRYGNVMASRGSVIPLFIRQV
                     VNGDAITITDPNMTRFMMTLDDAVDLVLYAFEHGRNGDIFVQKAPAATIDVLVKALLD
                     IMNEPRHPINVIGTRHGEKQYEALCSREEMFVAQEEGNYYRVPADNRDLNYSKYYEHG
                     DKNLSLVEDYNSHNTQQLDIEGMKTLLRKLDFIREIENGHLFIPEGV"
     gene            976..1857
                     /locus_tag="RH288_003351"
     CDS             976..1857
                     /locus_tag="RH288_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001507560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV4032381.1"
                     /translation="MNVMILGVTGMLGYSLFTNLKDYKNLNVIGTARNLLGKEQYFKT
                     QKQNLVLNIDATDIDSIDNVINSVDPDVVINCIGLIKQHEISKQHVEAIKINALLPHQ
                     LAEVCNKYNAKLIQFSTDCVFDGKKGLYRESDTPNSTDLYGKSKCLGEVNYGKHLTLR
                     TSIIGHELNSSVSLIDWFLSQSTEVNGYSKAIFSGLPTCYIAKLLAEKIIANDSLKGI
                     YHLSANPIDKYTLISLVSEIYGKSIKINKSEKLIIDRSLDSTRLREAIGFIPPSWYDL
                     IKFMFNDYVTRYSLCKN"
     gene            1845..2978
                     /gene="wecB"
                     /locus_tag="RH288_003352"
     CDS             1845..2978
                     /gene="wecB"
                     /locus_tag="RH288_003352"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001759324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDV4032382.1"
                     /translation="MQKLKVMTIVGTRPEIIRLSRIIAKLDAYCEHTLVHTGQNYDYE
                     LNQIFFDDLGIRTPDVFLECAGSSAAETMAQVISKSEDVFVKFQPDALLILGDTNSAL
                     AAITAKRNKIPIFHMEAGNRCFDLRVPEEINRKIVDHIADVNMPYSDIAREYLIREGL
                     RPDLIIKTGSPMDEVLTYYHDKIRASVIVQHLSLTANEYFLVSVHREENVDSDKNIHS
                     YVQVLNELAEKYKYPIIVSTHPRTRKKIEALNLQFHPLVNLLKPLGFSDYVRLQMDAK
                     VVLSDSGTITEESSILNFPALNIREAQERPEGFEEGVAMFTGMSIDRILQAINILESQ
                     PRGTTRLISKVSDYIAPNVSDKVLRIILSYTDYVNRVIWRKSL"
     gene            2975..4210
                     /locus_tag="RH288_003353"
     CDS             2975..4210
                     /locus_tag="RH288_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001507558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDV4032383.1"
                     /translation="MKLVLIIDDYLPDSTRVGAKMFHELALELQSRGHVITVITPNRQ
                     QNIPLLIEKYDGITIWRFRSGPIKDVGRIQRAMNETFLSLKAWKAVQSLISPSTFDGV
                     IYYSPTIFWGGLVRKIKKRCNCPSYLVLRDLFPRWVVDAGIIKEGSFIERYFRFFEKY
                     SYQQANCIGLMSERNLEVFQSSNVGYHCEILRNWASLTPVMKNEEILASGFKARLSLQ
                     GKIIFFYGGNIGHAQDMANLMRLARNMRSFEQAHFLFVGQGDEVVLINSLARDWELTN
                     FTYLASINQNDFKTLLSEIDVGLFSLSASHSSHNFPGKLLGYMVQSVPILGSVNAGND
                     LADLVNNSGAGFIHINGEDDKLLHSAKRLLLEPELRNKLGDAANTLLHEQFSVTAAAK
                     SIEQRLEADYACHHLYRVA"
     gene            4179..4583
                     /locus_tag="RH288_003354"
     CDS             4179..4583
                     /locus_tag="RH288_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015741767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /protein_id="HDV4032384.1"
                     /translation="MRVITCTELHELYDNARKSERLRAHLLLHSCHDDKVQRLFIGMV
                     KGSYVEPHFHELPHQWEMFIVMEGQIKVCLYNQSGAIVRAFVAGDDADSSVVEFAPGD
                     IHSVECISEQALMMEVKEGPFDSNYAKVFPNW"
     gene            4762..6168
                     /gene="gndA"
                     /locus_tag="RH288_003355"
     CDS             4762..6168
                     /gene="gndA"
                     /locus_tag="RH288_003355"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDV4032385.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAHT
                     FTDWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKEQRVAASKVLSGPKAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYHWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            6418..7584
                     /gene="ugd"
                     /locus_tag="RH288_003356"
     CDS             6418..7584
                     /gene="ugd"
                     /locus_tag="RH288_003356"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HDV4032386.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRYADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVDINPYAVMVIKSTVPVGFTAAMHKKYCTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            7731..8711
                     /gene="wzzB"
                     /locus_tag="RH288_003357"
     CDS             7731..8711
                     /gene="wzzB"
                     /locus_tag="RH288_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416531.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen chain length determinant protein
                     WzzB"
                     /protein_id="HDV4032387.1"
                     /translation="MRVENNNVSGQNHDPEQIDLIDLLVQLWCGKMTIIISVIVAIAL
                     AIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGPAVPKVSDIQASLIGRYSTA
                     FSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETPEVAQKQLAKYIQQVDDQVN
                     VELEKDLKDNIALRMKNLQDSLRTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQIQ
                     QTGEDITQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIESLKVDDLDIH
                     AYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNYNAK"
     gene            complement(8808..9407)
                     /locus_tag="RH288_003358"
     CDS             complement(8808..9407)
                     /locus_tag="RH288_003358"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDV4032388.1"
                     /translation="MLTEQLDWEKTDGLMPVIVQHAISGEVLMLGYMNPEALDKTVES
                     GKVTFFSRTKQRLWTKGETSGNFLNVVSIVPDCDNDTLLVLANPIGPTCHKGTSSCFG
                     DTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVH
                     DRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
     gene            complement(9401..10177)
                     /gene="hisF"
                     /locus_tag="RH288_003359"
     CDS             complement(9401..10177)
                     /gene="hisF"
                     /locus_tag="RH288_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDV4032389.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGA
                     DELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETL
                     DWVEEVQKRGAGEIVLNMMNQDGVRNGYDLKQLKKVREVCHVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINIGELKAYLATQCVEIRIC"
     gene            complement(10159..10896)
                     /gene="hisA"
                     /locus_tag="RH288_003360"
     CDS             complement(10159..10896)
                     /gene="hisA"
                     /locus_tag="RH288_003360"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDV4032390.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAE
                     VLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVG
                     STAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTG
                     VRGVIVGRALLEGKFTVKEAIACWQNA"
     gene            complement(10896..11486)
                     /gene="hisH"
                     /locus_tag="RH288_003361"
     CDS             complement(10896..11486)
                     /gene="hisH"
                     /locus_tag="RH288_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDV4032391.1"
                     /translation="MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFL
                     PGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDED
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM"
     gene            complement(11486..12553)
                     /gene="hisB"
                     /locus_tag="RH288_003362"
     CDS             complement(11486..12553)
                     /gene="hisB"
                     /locus_tag="RH288_003362"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HDV4032392.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQ
                     KAGYKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECD
                     CRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDRETLNWPMIGE
                     QLTKRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEI
                     NVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            complement(12553..13623)
                     /gene="hisC"
                     /locus_tag="RH288_003363"
     CDS             complement(12553..13623)
                     /gene="hisC"
                     /locus_tag="RH288_003363"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDV4032393.1"
                     /translation="MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVE
                     FQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDA
                     ILYCPPTYGMYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTG
                     QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFAL
                     AGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAER
                     EYLIAALKEISCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCL
                     RITVGTREESQRVIDALRAEQV"
     gene            complement(13620..14924)
                     /gene="hisD"
                     /locus_tag="RH288_003364"
     CDS             complement(13620..14924)
                     /gene="hisD"
                     /locus_tag="RH288_003364"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDV4032394.1"
                     /translation="MSFNTIIDWNSCTAKQQRQLLMRPAISASESITRTVNDILDNVK
                     ARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDERKQAMAVAVKNIETFHTAQ
                     KLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLC
                     SPPPIADEILYAAQLCGVQDVFKVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPAAD
                     MARRVAEAVERQLAELPRAETARQALSASRLIVTKDLAQCVAISNQYGPEHLIIQTRN
                     ARDLVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA"
     gene            complement(14930..15829)
                     /gene="hisG"
                     /locus_tag="RH288_003365"
     CDS             complement(14930..15829)
                     /gene="hisG"
                     /locus_tag="RH288_003365"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDV4032395.1"
                     /translation="MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFG
                     GCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     misc_feature    complement(15876..15999)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            complement(15975..16025)
                     /gene="hisL"
                     /locus_tag="RH288_003366"
     CDS             complement(15975..16025)
                     /gene="hisL"
                     /locus_tag="RH288_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HDV4032396.1"
                     /translation="MTRVQFKHHHHHHHPD"
BASE COUNT         4174 a         3744 c         3940 g         4365 t
ORIGIN      
        1 acggttttta aatacagaaa taaatgagat aagaattttt tcacgtgatg aaaaaaaaca
       61 agatgacatg cgtaaacatt tcaaatcaga taaattgaaa ttttatattg gtgatgtacg
      121 cgattatcag agtgtttcaa atgctatgcg cggcgttgac tatatatacc atgccgccgc
      181 tttaaaacaa gtaccttcgt gcgagttcta tcctttagaa gcggttaaaa caaatgtatt
      241 aggcaccgaa aatgttttag aagcagccat tactcatgga gtaaaaagag tagtatgtct
      301 aagtacagat aaagcagttt acccaatcaa tgccatgggg atttctaaag caatgatgga
      361 aaaagtcatc gttgccaaaa gccgcaattt aactcatacg aacacaactg tctgttgtac
      421 tcgttatggt aatgtcatgg cctccagggg atctgtgatt ccactgttta taagacaggt
      481 tgttaatggt gatgctatta ctattacaga ccctaatatg acccgtttca tgatgacatt
      541 agatgatgca gttgatcttg tcttatatgc ctttgaacat ggacgtaatg gagatatatt
      601 tgtacagaaa gcacctgctg ccactataga tgtattggtt aaagcattgt tagatattat
      661 gaatgaacca agacacccta ttaatgttat tggcactcgt catggtgaaa agcaatatga
      721 agcactatgt agccgtgaag agatgtttgt tgcgcaagag gaagggaatt attatcgagt
      781 gccagcagat aaccgtgacc tcaattattc aaagtattat gaacatggtg ataagaatct
      841 cagtctagtg gaggattata attctcataa tactcaacag ttagacattg aaggtatgaa
      901 gacccttctg cgcaaacttg atttcatccg tgaaattgaa aatggtcatc tgtttattcc
      961 tgaaggagta tgattttgaa tgtcatgatt ttaggtgtca cggggatgct tggctatagt
     1021 ctttttacca atctaaaaga ctataaaaac ctgaatgtaa ttggcacagc acgtaatctt
     1081 cttgggaaag agcaatattt caagacacaa aaacagaatc ttgttcttaa tatcgatgct
     1141 actgatattg atagcattga taacgtgatt aattcggttg accctgatgt tgttataaat
     1201 tgcattggcc taattaagca gcatgagatc tctaagcaac atgttgaggc tattaaaatt
     1261 aatgccttat tacctcatca attagctgaa gtatgcaata aatataatgc caagctaatt
     1321 caattctcaa cggattgtgt ttttgatgga aaaaaggggc tataccgtga atctgatacg
     1381 cctaattcaa cggatctata tggtaaatca aaatgtcttg gtgaagtcaa ttacggtaaa
     1441 catttaactc ttaggacatc tattataggt catgagctta attcttcagt aagcttaatc
     1501 gactggttct tgagtcaatc tactgaagtt aatggttatt caaaagcgat attttctggt
     1561 ctgccgactt gttatattgc taaattattg gctgaaaaga ttatagccaa tgatagcttg
     1621 aaaggaatat atcatctttc agccaatcca atagataaat acacattaat ctcattggtt
     1681 tcagagatat atggtaagtc tattaaaata aataaatccg agaagttgat aattgatcgc
     1741 tcgcttgatt caactagact gagggaagca ataggattta ttcctccatc gtggtatgac
     1801 ttgattaagt ttatgtttaa tgactatgtt acaaggtatt ctctatgcaa aaattgaaag
     1861 tgatgactat tgttggcact cgacctgaaa ttatcaggct atctcgtatc attgcaaagc
     1921 ttgatgctta ttgtgaacat actttggtac atactggtca aaactatgat tatgaactta
     1981 atcagatttt ttttgatgat ctaggtattc gtacacctga tgttttttta gaatgtgctg
     2041 ggagcagtgc tgctgaaact atggcacaag tcatcagtaa gtcagaagat gtatttgtaa
     2101 aattccagcc tgatgcatta ttaattcttg gtgatacgaa tagtgcatta gctgctataa
     2161 ctgccaaacg taataaaatt cctatttttc atatggaagc tggtaaccgc tgttttgact
     2221 tgcgtgtgcc agaggaaatt aataggaaaa ttgttgatca tattgcagat gttaatatgc
     2281 cttacagcga cattgcacga gagtatctga tcagagaagg gcttagacca gatttgataa
     2341 ttaaaacggg aagtccgatg gatgaggtgt taacttatta tcacgataaa attcgagctt
     2401 ctgtcattgt tcaacattta tccttaacag cgaacgagta ttttttggtt agtgttcatc
     2461 gtgaagaaaa tgttgattct gataaaaaca tccatagtta tgtacaagtg ttaaatgaat
     2521 tagctgaaaa atataagtat ccaattattg tttctactca cccaagaaca agaaagaaaa
     2581 tcgaggcgct aaacttacaa tttcatcctc tagtgaatct tctaaaacca ctaggattta
     2641 gtgattatgt tcgtttgcag atggatgcaa aagttgtatt aagtgatagc ggaaccatta
     2701 ctgaggaatc ttctattttg aatttccctg ctctaaatat tagggaagct caggaacgac
     2761 ctgaaggttt tgaagagggg gtggcgatgt ttacgggaat gagcattgat agaattttgc
     2821 aagcaattaa tattcttgaa agtcaacctc gtggaactac gaggttaata agtaaagtta
     2881 gcgattatat agcacctaat gtttcagata aagttcttcg gataattctg agttatactg
     2941 attatgttaa tcgtgttata tggagaaaat cgctttgaaa ttggtgctaa tcattgatga
     3001 ttatttgccc gatagtactc gagtaggcgc aaaaatgttt catgagttgg ctctcgaact
     3061 acagtcccgc ggacatgtca tcacggttat tactcccaat cgtcagcaaa acattccttt
     3121 actaatagaa aaatatgatg ggataactat ctggagattc aggagtggtc cgataaaaga
     3181 tgttggtcgt atccagcggg caatgaatga aacattcttg tcattgaagg catggaaggc
     3241 agttcagagt ttaatatctc cgtctacttt tgatggagta atttattact ccccaactat
     3301 tttctggggt ggtctggtta gaaaaatcaa gaaacgctgc aactgcccat catatcttgt
     3361 actccgggat ttgttcccca gatgggtggt tgatgctggg attataaaag aaggttcttt
     3421 tatagagagg tatttcaggt tttttgagaa atattcttat cagcaggcta attgtattgg
     3481 tcttatgtcc gagagaaatc ttgaggtctt tcagtctagt aatgtgggat atcactgtga
     3541 aatcctgagg aactgggcca gtttgacgcc tgtaatgaaa aacgaagaaa ttcttgcttc
     3601 gggatttaag gcgcgcttat cccttcaggg aaaaattatt tttttctatg gagggaatat
     3661 tggacacgct caggatatgg caaatttaat gcgtcttgct cgcaatatgc gctctttcga
     3721 gcaagctcat ttcctttttg tcgggcaagg tgatgaggta gtgctgataa attctctagc
     3781 aagagattgg gaattaacaa attttactta tttagcgtct attaatcaga atgactttaa
     3841 aaccctcctt tcggaaattg atgtcggttt gttctcactt tccgcaagtc attcgtcgca
     3901 taactttcct ggaaagctgt taggatatat ggtgcaatca gttcccattt tgggaagcgt
     3961 taatgcgggt aatgaccttg cggatttggt gaataacagt ggtgccggat ttattcacat
     4021 taatggcgag gatgataaac tgctccattc ggctaagcgt ttgttattag aacccgaatt
     4081 gcggaataag ttaggcgatg cggctaatac tttgttacat gagcaatttt cggtaactgc
     4141 tgctgcaaag tcaattgaac aaagactgga ggctgattat gcgtgtcatc acttgtaccg
     4201 agttgcatga gttatatgat aatgccagaa aatcagaaag actgcgtgca catttgctat
     4261 tgcattcttg tcatgatgac aaagttcagc gcctatttat tggcatggtt aagggcagtt
     4321 atgttgaacc ccattttcat gaattgccac atcagtggga aatgtttatt gttatggaag
     4381 gccagataaa ggtttgtctc tacaatcaat cgggagcgat cgtgagggca tttgttgccg
     4441 gtgacgatgc tgatagttct gtcgtggaat ttgctccggg agatatacat agcgtagagt
     4501 gtatctctga gcaagcactg atgatggagg ttaaggaagg cccgtttgac tcgaattatg
     4561 ccaaggtgtt tccgaattgg taattaatgt ttcttatcga aaataataat gctgatattt
     4621 gatctttttt atcatttcac atgacccctg attgtctgga gcatcttccg ctatccccaa
     4681 agcctgaaac tgagttaaca tctacgatac attgaacccg cgcatgcgtc gcgcggtgac
     4741 cacaccagac aggagtaaac aatgtcaaag caacagattg gcgtcgtcgg tatggcagtg
     4801 atgggacgca accttgcgct caacatcgaa agccgtggtt ataccgtctc tattttcaac
     4861 cgttcacgtg aaaagacgga agaagtgatt gccgaaaatc caggcaagaa actggttcct
     4921 tattatacgg tgaaagaatt tgttgaatct ctggaaacgc ctcgtcgcat cctgttaatg
     4981 gtgaaagcag gtgcaggcac ggatgctgct attgattccc tcaagccata cctcgataaa
     5041 ggcgacatca tcattgatgg tggtaatacc ttcttccagg acactattcg tcgtaaccgt
     5101 gagctttctg ctgaaggctt taacttcatc ggtacgggtg tttccggtgg tgaggagggt
     5161 gcactgaaag gtccttccat catgcctggt ggccagaaag aagcctatga actggttgca
     5221 ccgatcctga ccaaaatcgc tgctgtggct gaagatggcg aaccgtgcgt tacctatatt
     5281 ggtgccgatg gtgcaggtca ctatgtgaag atggttcaca acggtattga atacggcgat
     5341 atgcagctga ttgctgaagc ctattctctg cttaaaggtg ggctgaacct ctccaatgaa
     5401 gaacttgcac acacctttac cgactggaat aacggtgaac tgagcagcta cctgatcgac
     5461 atcaccaaag acatcttcac taaaaaagat gaagacggta actacctggt tgatgtgatc
     5521 ctggatgaag cggctaacaa aggtaccggt aaatggacca gccagagtgc gctggatctc
     5581 ggcgaaccgc tgtcgctgat aaccgagtct gtgtttgcac gttatatctc ttcactgaaa
     5641 gagcagcgcg ttgccgcgtc taaagttctc tctggcccga aagcacagcc ggcaggtgac
     5701 aaggctgagt tcatcgaaaa agttcgtcgt gcgctgtatc tgggcaaaat cgtttcttac
     5761 gcccaaggct tctctcaact gcgtgctgcg tctgaagagt accactggga tctgaactac
     5821 ggcgaaatcg cgaagatttt ccgtgctggc tgcatcatcc gtgcgcagtt cctgcagaaa
     5881 atcactgatg cttatgccga aaatccgcag atcgctaacc tgctgctggc tccgtacttc
     5941 aagcaaatcg ccgatgacta ccagcaggcg ctgcgcgatg tcgtcgctta cgcggtacag
     6001 aacggtatcc cggttccgac cttcgccgct gcggttgcct attacgatag ctaccgtgcc
     6061 gctgttctgc ctgcgaacct gatccaggca cagcgtgact atttcggcgc acatacttat
     6121 aagcgcattg ataaagaagg tgtgttccat actgaatggc tggattaatc tgatttaacc
     6181 aacaataaaa ttgaggcccg gtgtatattg caccgggctt ttttttgtca atatatctta
     6241 tagactaaat ttcactgctt aatattaact taataaatat cagctattct tataaagaaa
     6301 atctgaattg tttttcgttg cgttgaccat cgaacaacgt agcgttaaaa catttagttc
     6361 ttatcaggat gctaaaaaca tcatgattca cagttaagtt aattctgaga gcatgaaatg
     6421 aaaatcacca tttccggtac tggctatgta ggcttgtcaa acgggcttct aatcgcacaa
     6481 aatcatgagg ttgtggcatt agatatttta ccgtcacgcg ttgctatgct gaatgatcgg
     6541 atatctccta ttgtggataa ggaaattcag cagtttttgc aatcagataa aatacacttt
     6601 aatgccacat tagataaaaa tgaagcctac cggtatgctg attatgtcat catcgccact
     6661 ccaaccgact atgatcctaa aactaattat ttcaatacat ccagtgtaga atcagtaatt
     6721 aaagacgtag ttgatattaa tccttatgcg gttatggtga tcaaatcaac tgttcccgtt
     6781 ggttttaccg cagcgatgca taagaaatat tgcactgaaa atattatatt ctcacccgaa
     6841 ttcctccgcg aaggtaaagc cctttacgat aatctccatc cttcacgtat tgtcattggt
     6901 gagcgttcag aacgcgcaga acgttttgct gcgttgttac aggaaggagc gattaagcaa
     6961 aatatcccga ccctgtttac cgactccact gaagcagaag cgattaaact ttttgcaaac
     7021 acctacctgg cgatgcgcgt ggcgtacttt aacgaactgg atagctacgc agaaagttta
     7081 ggtctgaatt cccgtcaaat aatcgaaggc gtttgtctcg acccacgaat tggcaaccat
     7141 tacaacaatc cgtcgtttgg ttatggtggt tattgtctgc cgaaagatac caagcagtta
     7201 ctggcaaact atcagtctgt gccgaataac ctgatctcgg caattgtcga tgctaaccgc
     7261 acgcgtaaag actttattgc cgatgccatt ttgtcacgca aaccgcaagt ggtgggtatt
     7321 tatcgtctga ttatgaagag cgggtcagat aacttccgtg cgtcttctat tcaggggatt
     7381 atgaaacgta tcaaggcgaa aggcgttgaa gtgatcatat acgagccagt gatgaaagaa
     7441 gactcattct tcaactctcg cctggaacga gatctcgcca ccttcaaaca acaagccgac
     7501 gtcattattt ccaaccgtat ggcagaagag cttaaggatg tggcagacaa agtctacacc
     7561 cgcgatctct ttggcagtga ctaacatcct gttatcaggg cgattttcgc cctgattctc
     7621 ttatgttccc tttgtaataa ttcattcttt ttatcattta tcctatagca ttcatggcga
     7681 ttatcgctaa actatggcga cttaaaatta tttcgtccgt tagggtaatg atgagagtag
     7741 aaaataataa tgtttctggg caaaaccatg acccggaaca gattgatttg attgatttac
     7801 tggtgcagtt gtggtgcggc aagatgacta tcatcatttc tgtcattgtg gctattgccc
     7861 tggctatagg gtatctggcc gttgccaaag aaaagtggac ttccacagct attgttactc
     7921 aacctgatgt ggggcaaatc gctggttata ccaacgcgat gaatgtgatt tacggtccgg
     7981 ctgtaccgaa agtctccgac attcaggctt cgcttatcgg acgttacagc actgcattct
     8041 cagcattagc ggaaacgctg gataaccagg aagaagcaga aaagctgacc attgagccta
     8101 ccgttaaaaa tcagtcatta cctttagcgg tgtcttatgt tggtgaaaca cctgaagttg
     8161 ctcagaagca gctggcgaag tatatccagc aagttgacga ccaggtaaat gtagagctgg
     8221 aaaaagactt gaaagacaat atcgcgctgc gtatgaaaaa cttgcaggac tctttaagaa
     8281 ctcaggaagt agtcgcgcaa gagcagaaag atctgcgtat ccgtcagatt caggaagcgt
     8341 tgcagtatgc gaatcaggcg caggtgacaa aaccgcaaat tcaacagact ggcgaagata
     8401 tcacgcaaga tacgttgttc cttttgggga gcgaagcgct ggagtcgatg attaagcatg
     8461 aggcgacccg tccgttggtg ttctcaccaa actactatca gactcgtcaa aacctgctgg
     8521 atatcgaaag cttaaaagtt gatgatcttg atattcatgc ttaccgttat gtgatgaaac
     8581 cgacgttacc tattcgtcgc gatagtccga aaaaggcaat taccttgatt ctggcggtgc
     8641 tgctgggtgg catggttggc gcggggattg tgctggggcg taatgctcta cgcaattaca
     8701 acgcgaaata atctttgcag ctttaaagaa aacgggaagg gtggtgacac cttgcccgtt
     8761 ttttttgccg gatgcgacaa caacatcgca tccgcttacc ccgcaactca ctgatgccgt
     8821 ttacgcaggt tctcaattac cgtagttaaa tccagatcct gatcctgcaa cagcaccagc
     8881 aggtgataca tcaaatcaga cgcctcgttg gtcagctcaa agcggtcatg taccgttgcg
     8941 gcaagtgcgg tttccacgcc ttcttcgccc actttctgcg caatgcgttt ggtgccgctg
     9001 gcatacagtt tggcggtata ggaggtttcc ggatcggcag atttgcgttc ggcgagcaat
     9061 tgttccagtt gatacaggaa cagccactgg tgagctgtgt cgccaaagca gctactggtg
     9121 cctttatggc aggtcgggcc gatgggattc gccagtacca gtaacgtgtc gttgtcgcag
     9181 tccgggacaa tgctcactac gttgaggaaa ttgcctgatg tttcgccttt ggtccacagc
     9241 cgctgtttag tgcgcgagaa gaaggtgact ttgccgcttt cgacggtttt gtccagagct
     9301 tccgggttca tatagcccag cattaacact tcgccggata ttgcgtgttg cacaattacc
     9361 ggcatcagtc cgtcggtttt ttcccagtcc agttgttctg ttaacatatc ctgatctcca
     9421 cgcactgtgt tgccaggtac gcttttaatt caccaatatt gattatttgt ttgtggaata
     9481 cggaagctgc cagcgcgccg tcaacgtcgg catcgcggaa ggcttcgagg aagtgttcca
     9541 tggtgcccgc gccaccggag gcaatcagcg ggacgtggca aacttcacgc acttttttca
     9601 gttgtttgag gtcgtaaccg ttacgcacgc cgtcctgatt catcatgttg aggacgattt
     9661 ctccggcacc gcgtttttgc acttcctcta cccagtcgag tgtttcccac tgagtaacgc
     9721 gggtgcggct ttcatcgccg gtatattgat tcacatgata tttaccggtt tcggcgtcgt
     9781 accaggtatc aataccaacc acaatacact gcacgccaaa gcgatccgcc aggcgagtaa
     9841 ttaacgtcgg gtccgccagt gcaggcgagt tgatggaaat tttatccgcg ccaaaggaaa
     9901 gaattttcgc ggcatcttcc agagacttaa tcccacccgc cacgcagaac ggaatgtcga
     9961 tcacttccgc cacgcgagat acccagcttt tatctaccac acgaccatcg ctggaagcgg
    10021 tgatatcgta gaacaccagt tcatctgcac cttcttcggc gtagcgtttt gccagcggca
    10081 cgatatcgcc aatgatttca tggttgcgaa actgtacgcc tttcaccacc tgaccatcac
    10141 gaacgtcgag acacgggatt atgcgttttg ccagcatgcg atggcctcct tcacggtgaa
    10201 tttaccttcc agtaatgcac gaccaactat tacgccgcgc acgccagtac cacgcagggc
    10261 cgcgacatca tcaatgtcgc caatgccgcc ggatgactga aatgccacct gcggatatct
    10321 ggcgcacact tcttcatata aagagacgtt agaacctgcc agcgtgccgt cgcgcgagat
    10381 atcggtacac agcacatgtt tcaggccgac gggcagatag gtttccacca gttgttccag
    10441 tgaaacgccc gagttctctt gccagccgct gactgccacc tgcttgttgc cttgctcgtc
    10501 aatacggaca tccagcgcca gcactaaggc atcggcaccg aaacgttcaa accagccttt
    10561 caccatttct ggtgatttca ccgcggtgga gccgaccact acgcgcgcaa cgcccgcttc
    10621 cagtaacgcc gccacgtctt cttcgctacg cacgccgccg ccaacctgca ccggaacgtt
    10681 aacgcccgcg accagggttt taatcagcgg gatttgacgt ttagccggat cttttgcccc
    10741 ggtcagatcc accagatgca acacttcggc accttgtgcg gcgtaatcct gtaagcgagg
    10801 cagcgggtcg ttaccgtaat cgcgctgttt gccgtaatcg ccctgatgga gacgcaccac
    10861 agtgccgtcg attaaatcta atgccggaat aatcatcaca tctccaggaa gtttttcagc
    10921 aacttagcgc cagcggcacc agaacgctcc ggatggaact gcacgccgta gaagttatct
    10981 ttttgtaccg ccgcggtgaa cggttcgccg tagttacact gggcgatggt ccacggattg
    11041 accggcattg cgtaactgtg aacaaagtaa aagtacgcac cgtcttcaat cccctgaaac
    11101 aggcggttgc ctgcctgcgg gtaaacgcgg ttccagccca tatgcggcag gggcagacca
    11161 aagtcggtca ttttcggcac gtcttcgtcg atgatgccca gcaaatcgac gccgttgctc
    11221 tcttcgctgc gccgccccag cagttgcatc cctaagcaga tgcccagcac cggttgggta
    11281 caggctttga tgagatcaaa cagctcgcgc tcacgcacct gatccatcgc tgcttgcgca
    11341 gtgccaacgc cgggtaaaaa cagtttatcg gccagcaaca cgacgtccgg gtcacggctg
    11401 actttgggtt cataaccgtg gcgcgcaatg gcagacttca ccgagttcag gttggcgcag
    11461 ccggtatcaa ggatcaccac gttcattaca gcactccttt cgacgagggc agggtgtcgc
    11521 cttccacgcg gatggcctgg cgcagggtgc gaccaaaggc tttaaagaga ctctctacac
    11581 ggtgatgatc gtttttacct ttggttttca ggtggagcgt cacgcccatg gtgtaagaga
    11641 gcgaacggaa gaagtgctcg atcatctcgg tgctgagatc gcccacgcgc tggtaggtaa
    11701 actcggcttt atattccagg tgcgggcgac cagagatatc cagcgcgcag cgggcaaggc
    11761 attcgtccat cggtagcaca aaaccaaagc gacaaatacc gcgtttatcg ccgagggcaa
    11821 tttttaacgc ttcgcccagc gccaggccgg tatcttcgac ggtgtggtga tcgtcgatat
    11881 agaggtcgcc tttgacgttg atttccatac ggaagccgcc gtgagtagcg atctgatcca
    11941 gcatgtgatc aaagaagcca acaccggtgt taatcttgct gccaccttcg cgatccagcc
    12001 acacctgaac gtcaatttgc gtctctttgg tgttgcgcac tacatgggcg taacggtctc
    12061 gtttagtgag ttgctcgcca atcatcggcc agttcagggt ttcacggtcg tagcgtaaac
    12121 cattaatgcc catgttttcc gccagttgaa tgtcggtcgc gcgatcgcca atcacataac
    12181 tgttggcgcg atccatcgct tgctcagcga gataacgctc caccagtttt actttcggtt
    12241 tacggcagtc gcactcatcg gcgggcaggt gcggacaaat tagcacttca tcaaactgca
    12301 cgccttgcga ggtgaagatc tgcatcatca ggttgtgcgg gccatcgaaa tccgcttgcg
    12361 ggaaactttg tgttccaaga ccatcctgat tagtgatcat caccagtttg tagcccgctt
    12421 tttgcagctt cagcagctcc gggatcacgc ccggttcaaa ggcgagtttg tcaaaacggt
    12481 ccacctgaaa atcactcggc ggttcgctaa tcagggttcc atcgcgatcg ataaaaagat
    12541 acttctgact cattaaactt gctccgcacg taaggcgtca atgacgcgct ggctttcttc
    12601 acgggttccg acggtaattc gcaggcagcc gcttaaagag ggttgtttat tctgatcacg
    12661 taagataatg ccctgatccc acaaagattt aaacactgcg ctggaggctt taaagcgcgc
    12721 cagaatgtag ttggtttcag agtcaaaaac ctgctccacg caggagattt ctttcagtgc
    12781 ggcaatcagg tattcgcgct ctgcaataat ttgcgccacc cgttcgcgca tggcgacgat
    12841 cccctgcggg cttaacgcct gggccgcaat gtcggcaacc ggcgttgaga gcgggtaggg
    12901 ggcgatcact ttcatcagca ggttgatgac ttcttcgttt gccagcgtaa atccgcaacg
    12961 aagtcccgcc agagcaaaag ctttcgacag tgtgcgtaaa atagccaggt gcggatattc
    13021 cgccagccag ccagccagcg atgcctgtgg gcaaaactcg atataggctt catcggcaac
    13081 cacaatggct tttccgcggg ttaactccag caaggtgcga aaatcctgcg gattgatcag
    13141 ttgcccggtc gggttgttgg ggctgcaaac atagaccact tttacgccgt ccagcttgtc
    13201 ggaaatgccc tgcaagtcca gttgccagtt gtccagcgtc ggcactgtgc ggcactcgac
    13261 gccaatggtt tcagcgctga cgctgtacat gccgtacgtt ggcgggcagt agaggatggc
    13321 gtctttacct ggttcgcaaa aagcgcgaat cagcagttca ataccttcgt ccgcgccacg
    13381 gctaaccagc acctgttccg gtttcacgcc tgcatactgt gcataatttt caatcaccgc
    13441 tttcggctga cattctgggt agcggttgag tgtttgctga gtaagctgaa actccacggc
    13501 tgtggggtat tcgttggcgt tcagccagac gtcgccgtta ccgcccagac ggcgcgctga
    13561 ctgatacggc gtcaggttgc ggacgttttc acgcgctaaa tcggtaatag tcacggtgct
    13621 catgcttgct ccttaagggc gttaacacgc aaagtaacgg catttttgtg ggcggtcagg
    13681 cgctcggcgg cggctagtgt ttctatggtt gaagccagcg cggagaaccc ttctttcgac
    13741 agttcctgca cggtcatacg cttctggaaa tcagccaggc cgaggctgga acacgtcgcg
    13801 gtataaccgt aagtcggtag tacgtggttg gtaccggagg catagtcgcc tgccgattcc
    13861 ggtgaccagt caccaagaaa taccgaaccg gcgctggtga tgccatcgac cagatcgcgg
    13921 gcgttgcggg tctggatgat caggtgctcc gggccgtact ggttggagat tgccacgcac
    13981 tgcgctaaat ccttggtgac gatcagacgg ctggcgctca gtgcctgacg ggcggtttca
    14041 gctcgcggca gttctgccag ttggcgttcg acagcctcgg caacgcgacg cgccatatca
    14101 gcagcgggcg tcagtaaaat cacctgtgag tccgggccgt gttcagcctg ggagagcaaa
    14161 tcagaagcca cgaaatccgg cgtagcgccg ctgtcagcaa tcaccagcac ttccgacggg
    14221 cctgcgggca tatcgatcgc cgcaccgtcc agacgctggc ttacctggcg ttttgcttcg
    14281 gtaacaaagg cgttgcctgg cccgaagatt ttgtccactt tcggcacaga ttccgtacca
    14341 aacgccagcg cggcaatggc ctgtgcgccg ccgactttaa acacgtcctg cacgccgcac
    14401 agctgcgccg cgtaaaggat ctcatcggca atcggcggtg gtgagcacag caccactttt
    14461 ttacagcccg caatacgcgc cggagtcgcc agcattaata ccgttgagaa gagcggggcg
    14521 gagccgccag gaatatacaa acccactgaa gccaccgggc gcgtgacttg ctggcaacgt
    14581 acgcctggct gcgtttctac atctaccggc ggcagttttt gcgcagtgtg gaaggtttca
    14641 atattcttta ctgccaccgc catcgcctgt tttcgctcgt cgctcaggcg ttcgctggct
    14701 gcggcgatct cctcagcaga caccttcagc gcggtaaccg tggttttatc aaacttcgcg
    14761 ctgtattcac gcagggcctc atcgccgcgt gctttcacgt tatcgaggat atcgttaaca
    14821 gtgcgggtaa tgctttcaga agcggagatc gccgggcgca ttaacagctg gcgttgttgc
    14881 tttgcagtac agctattcca gtcaatgatt gtgttaaagc tcatggcgat cactccatca
    14941 ttttctcaat cggcaggacc aggattgaac tggcgcccag cgctttcagt ttttccatcg
    15001 tttcccagaa cagggtttcg ctactgacca tgtgcatcgc tacgcgttgt tggtcacccg
    15061 ccagcggcag aatggttggg cgttcggcac ctggcagcag ggcgatgact tcatccagac
    15121 gttcggtcgg tgcgtgcatc atgatgtatt ttgattcgcg cgcctggatc acaccctgaa
    15181 tacgggtcag cagtttgtcg atcagttgct gtttggattc ttccatttcg ccatcgcgtt
    15241 gaatcaggca ggctttcgag cgatagataa cttcgacttc gcgcaggccg ttagcttcca
    15301 gcgtggcacc ggtggaaacc agatcgcaaa tcgcatccgc cagtccggca cgcggggcga
    15361 cttcaacaga accgttcagt aagcaggatt taaaagagat gcctttctgg tcgagataac
    15421 gcttgagcag gtgaggataa gaggtggcga tacgtttacc gtttaaggag agcggaccgt
    15481 cccaggcttc atcaaccggc gttgccagcg aaagacgaca gccgccgaaa tccagacgac
    15541 gcagggtaaa gtagcgtgga tcttcaccct gggcgcggcg gttaagcagc tcttcttcca
    15601 gcacgttttc gccgataatc ccaaggtcta ccacgccatc cattaccaga ccgggaatgt
    15661 cgtcgtcacg cacgcgcaga atatcaatcg gcatgttttc tgccatcgcg atcaggcgct
    15721 gggtgtgaag attaatttta atgccacagc gcgccagcaa ttcgcgtgag tcatcactta
    15781 aacggccgga tttctgcata gctatgcgta aacgagtgtt gtctgtcatt ttgttattcc
    15841 tctttaaacc tgtctgaacc gttatcaacc gcgcaataaa aaagcccccg gaaggtgatc
    15901 ttccgggggc tttctcatgc gttcatgcac cactggaaga tctgaatgtc ttccagcaca
    15961 catcgcctga aagactagtc aggatgatgg tgatgatggt ggtgtttaaa ttgaacgcgt
    16021 gtcataaaag tctctgtgaa tgtttattca actgatgtct attaacctaa accactttca
    16081 cgttagaaag caagggcttt tttatatatt ttatggcaat ggatttgttt aatgaatgag
    16141 cggggaaagg agggggctaa gaggactgtc ctctaagctg acggcaccaa aaatagcgaa
    16201 gcctggattt tcgtctcact gac
//
LOCUS       DAPHKZ010000100        16215 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.100, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000100 DAPHKZ010000000
VERSION     DAPHKZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16215
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.100"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(34..410)
                     /gene="rnpB"
                     /locus_tag="RH288_003367"
     ncRNA           complement(34..410)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RH288_003367"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(443..1588)
                     /gene="garK"
                     /locus_tag="RH288_003368"
     CDS             complement(443..1588)
                     /gene="garK"
                     /locus_tag="RH288_003368"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417593.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HDV4032397.1"
                     /translation="MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADG
                     GEGTVEAMIAATQGAERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAE
                     KRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
                     IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAM
                     IVELDNNLSHYAEVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTAL
                     NLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTDDVGVVH
                     QHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG"
     gene            complement(1685..2575)
                     /gene="garR"
                     /locus_tag="RH288_003369"
     CDS             complement(1685..2575)
                     /gene="garR"
                     /locus_tag="RH288_003369"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDV4032398.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAA
                     GAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGT
                     ADHSALACYYEKLAKVEVTR"
     gene            complement(2605..3375)
                     /gene="garL"
                     /locus_tag="RH288_003370"
     CDS             complement(2605..3375)
                     /gene="garL"
                     /locus_tag="RH288_003370"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HDV4032399.1"
                     /translation="MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWL
                     VLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVET
                     KEEAELAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAP
                     VEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK"
     gene            complement(3391..4725)
                     /gene="garP"
                     /locus_tag="RH288_003371"
     CDS             complement(3391..4725)
                     /gene="garP"
                     /locus_tag="RH288_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GarP"
                     /protein_id="HDV4032400.1"
                     /translation="MILDTVDEKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEV
                     AKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGF
                     VDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
                     LALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISE
                     NGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIY
                     LVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLL
                     ASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGN
                     VASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK"
     gene            5100..6671
                     /gene="garD"
                     /locus_tag="RH288_003372"
     CDS             5100..6671
                     /gene="garD"
                     /locus_tag="RH288_003372"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HDV4032401.1"
                     /translation="MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLE
                     LIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTL
                     PLATKVPEPLPPLEGYTFEGYRNDDGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKL
                     QPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            6820..7155
                     /gene="prlF"
                     /locus_tag="RH288_003373"
     CDS             6820..7155
                     /gene="prlF"
                     /locus_tag="RH288_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PrlF"
                     /protein_id="HDV4032402.1"
                     /translation="MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHY
                     EILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVN
                     IDDEIGDDE"
     gene            7155..7619
                     /gene="yhaV"
                     /locus_tag="RH288_003374"
     CDS             7155..7619
                     /gene="yhaV"
                     /locus_tag="RH288_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ribonuclease
                     toxin YhaV"
                     /protein_id="HDV4032403.1"
                     /translation="MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKA
                     ATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRLFFRYSEK
                     EKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTRETEETH"
     gene            complement(7674..8483)
                     /gene="agaR"
                     /locus_tag="RH288_003375"
     CDS             complement(7674..8483)
                     /gene="agaR"
                     /locus_tag="RH288_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aga operon transcriptional regulator AgaR"
                     /protein_id="HDV4032404.1"
                     /translation="MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVS
                     TVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVE
                     LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
                     RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERII
                     VVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE"
     gene            8732..10012
                     /gene="kbaZ"
                     /locus_tag="RH288_003376"
     CDS             8732..10012
                     /gene="kbaZ"
                     /locus_tag="RH288_003376"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaZ"
                     /protein_id="HDV4032405.1"
                     /translation="MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPL
                     LIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPA
                     AQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
                     EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWP
                     RIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLV
                     IDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSH
                     YHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQY
                     VKVRSGELQPTPRELIINHIQDILAQYHTACEGQ"
     gene            10035..10508
                     /gene="agaV"
                     /locus_tag="RH288_003377"
     CDS             10035..10508
                     /gene="agaV"
                     /locus_tag="RH288_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417602.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HDV4032406.1"
                     /translation="MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQ
                     QNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRI
                     NVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKTAGVECFVQGVPTEPAVDLFKLL"
     gene            10519..11298
                     /locus_tag="RH288_003378"
     CDS             10519..11298
                     /locus_tag="RH288_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HDV4032407.1"
                     /translation="MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLG
                     DLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPF
                     AVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGIFYFLCAFLPIY
                     FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAW
                     LKLPVLAIAAAALAMALIDLLRKSPEPTQPAAQKEEFEDGI"
     gene            11288..12166
                     /locus_tag="RH288_003379"
     CDS             11288..12166
                     /locus_tag="RH288_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDV4032408.1"
                     /translation="MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRV
                     AWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVT
                     FVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
                     ILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGA
                     LVATYVRLSTTLEITAGDAVVKLQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLI
                     AVTVVLGIVGKFCHFL"
     gene            12184..12618
                     /locus_tag="RH288_003380"
     CDS             12184..12618
                     /locus_tag="RH288_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDV4032409.1"
                     /translation="MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALL
                     TSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLAMQKPGCEVITGTNLQLLLEMVL
                     EREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI"
     gene            12615..13748
                     /gene="nagA"
                     /locus_tag="RH288_003381"
     CDS             12615..13748
                     /gene="nagA"
                     /locus_tag="RH288_003381"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDV4032410.1"
                     /translation="MTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPAGVTERDA
                     ELLCPAYIDTHVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTTPLNTIHAA
                     LKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHT
                     LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMT
                     GLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGM
                     PDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLH
                     PARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF"
     gene            14099..15253
                     /locus_tag="RH288_003382"
     CDS             14099..15253
                     /locus_tag="RH288_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AgaS family sugar isomerase"
                     /protein_id="HDV4032411.1"
                     /translation="MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNF
                     LEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA
                     HPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALL
                     MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGV
                     FGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDET
                     LVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFI
                     DVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA"
     gene            15266..16126
                     /gene="kbaY"
                     /locus_tag="RH288_003383"
     CDS             15266..16126
                     /gene="kbaY"
                     /locus_tag="RH288_003383"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaY"
                     /protein_id="HDV4032412.1"
                     /translation="MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSP
                     VILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAM
                     IDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
                     KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFV
                     RRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN
                     VCGSANRISA"
BASE COUNT         3888 a         4301 c         4180 g         3846 t
ORIGIN      
        1 aaaaacccgc cgaagcgggt ttttacgtaa atcaggtgaa actgaccgat aagccgggtt
       61 ctgtcgtgga cagtcattca tctaggccag caatcgctca ctggctcaag cagcctaccc
      121 gggttcagta cgggccgtac cttatgaacc cctatttggc cttgctccgg gtggagttta
      181 ccgtgccacg gactgttacc agccgcgcgg tgcgctctta ccgcaccctt tcacccttac
      241 ctgatcccgc ttgcgcgggc catcggcggt ttgctctctg ttgcactggt cgtgggtttc
      301 ccccccaggc gttacctggc accctgccct atggagcccg gactttcctc ccctccgccc
      361 gtctcccccg aagaggacga cgacgaagcg gcgactgtct ggtcagcttc ggcgcgcagt
      421 atagagggtt tgcgcgccct tgtcaccccg cgttgcgcat tccaatcgcc agtgtcgcgg
      481 cgatattacg tgaagcacgg cagatattgt cataagcccc gcggaatgct tcgtccaacg
      541 tacctatgct ggtcaatacg ctgaagaccg catcaatgcc atgctgatgt acaacgccaa
      601 catcatcggt caggctaccc gcaatgccaa tcaccggttt atggtacttc ttcgccacgt
      661 ttgcgacacc aatcggtacc ttcccgtgaa tactctggct gtcaatacgc ccttcaccgg
      721 tgatcaccag cgtacaatcg tgaatatgtt cctccagatt cagcgccgta gtgacgattt
      781 caataccact tttcagttcc gcaccaagaa acgccattag cgccgcgccc ataccacccg
      841 cagctcctgc accggggaca tctttcacat caacatgcag cgctttttta atgacctcgg
      901 catagtgaga gaggttattg tccagctcaa caatcatcgc ttcactggct cccttttgtg
      961 ggccaaagat gcgcgatgcg ccgttatcgc ccaccagcgg attggtgaca tcacaagcga
     1021 cgcgaatgac gcaatctttt aagcgcggat cgaggccgga aatatcaata tcattcagag
     1081 tattaagact accgccgcca aaaccaattt cattgccgtt ggcgtcgcat aatttcgccc
     1141 ccagcgcctg taccatgcct gcgccgccat catttgtagc gctgccgcca atgccgataa
     1201 taatgtttgt cgcaccgctc tccagcgcct gcaggattaa ctcgcctgtg ccgcgtgaag
     1261 tggtcacgag tggatcgcgt ttttccgcag gtaccagctc cagcccactg gccgccgcca
     1321 tttcaataaa cgcggttttg ccatcgccgg agatccccca actggcattc actttctcgc
     1381 ccagcggccc tgtaacccag gcgtgacgtt cagccccctg ggtggctgca atcatcgctt
     1441 ccaccgttcc ttcgccaccg tcggcaaccg gaacagaaac gtactgtgca tcaggaaaaa
     1501 tttcccgaaa tcctttttct atcgcctgcg caacctcgct ggcagataaa ctttctttat
     1561 aagagtctgg ggcgattacg attttcatac ctatgcctgt taccacatga cgccggaggg
     1621 cgtttctctt attcggcctg gattccaggc ccggattgca atacgccatc cgggcacgac
     1681 gtcattaacg agtaacttcg actttcgcca gtttttcgta gtagcacgcc agggcgctat
     1741 gatccgccgt tcctaaacca tctgctcgca gtgcctgcat catctccata accgcagctg
     1801 tgagcggcag ttgtgcgccg acgccgtgag aagtatccag cgcattcgcc agatccttaa
     1861 tatgcagatc aatacggaag cccggcttga agttgcggtc catcaccatc ggcgctttgg
     1921 catccagcac ggtactgccc gccagtccac cgcgaattgc ctgataaacc aggtccgggt
     1981 taacgcccgc tttagttgcc agcgttaacg cttctgacat cgcggcaata ttcagcgcca
     2041 caatgacctg atttgccagt ttggtgacgt tacctgcacc gatttccccg gtatgcacca
     2101 cggaacccgc catcgctttc atcaaatcat agtatttgtc gaaaatagcc ttgtcgccgc
     2161 ccaccatcac tgacagcgta ccgtcgatgg ctttcggttc accgccgctc accggagcat
     2221 ccagcatatc aatgcctttc gctttcagcg cttcgctgat ttcacggctt gccagcggtg
     2281 cgatagaact catatcgatc aataccgtac ctggcttcgc gccttcaata atgccattct
     2341 cacccagcgc cacctctttc acatgagggg agtttggcag catggttatg atgacgtcgc
     2401 actgttcagc gatcgcttta gccgtagacg ctgtttctgc acctgcagca atcacgtcag
     2461 caatagcttc tgggttacgg tcagcaacca ccagcgagta acctgctttc agaaggtttt
     2521 tactcattgg tttacccata atccccaggc caataaaacc aactttcata gtcatatcaa
     2581 tcatctctct tgttgcggtg gtggttattt tttaaaggta tcagccagtt tctgagtggc
     2641 agagcggaag acgccgagat cgctgccgac agccacaaac gtcgcgcccc attccagata
     2701 acgacgcgca tcggcttcga ccggcgcgag gataccgctg ggtttgccgt gcgcgctggc
     2761 acggttaaaa atgtgctgaa ttgctttttg tacatccggg tgtgatgcat tgccgagatg
     2821 gcctaatgcc gcggccagat cgctggggcc gacgaagatg ccgtctacgc cttcggtagc
     2881 ggcaatggca tcgacgttat ctacgccctg ctgactttct atctggacca gaatagtgat
     2941 gttcttgttc gactgagcga aataatccgc cacggtgcca aacatattgg cgcggtgaga
     3001 aacggagacg ccgcgaatgc cttccggtgg gtaacgggtt gatgccaccg ccagctctgc
     3061 ttcctctttt gtttctacaa aaggaatcag gaagttatag aaaccgatat ccagaagacg
     3121 cttaataatt accggctcgt tggtcggcac tcgcactact ggcgcgctgg cgctgccttt
     3181 caaggccatt aactgcggaa taaacgtgga gatatcgttt ggcgcatgtt cgccatccag
     3241 caccagccag tcaaacccag ccaaaccaag aacttcagtg ctaatcgggt tagagagtgc
     3301 tgaccagcaa ccaatttgta cctgtttcgc agccagtgcg gctttgaatt tattcgggaa
     3361 aacatcgtta ttcatcgctt atacctttgc ttatttctgc aattccatac gtttaatgtc
     3421 gccaactacg aagaggtagc agaccatcgc catcagcgct gaacatccca cgaaaaccag
     3481 tgctgcattg aaggagtgca gttcacttac caggtagcca atcaccagtg gagtgacaat
     3541 ggaggcaaca ttgccaaaga cgttaaagac gccgccgcag aggccaacaa tctctttcgg
     3601 cgcggtgtca gaaatcaccg gccagcccag cgcaccaaat cctttgccaa agaaagccag
     3661 cgccatcagc atgaccacca gcgtggtgtt gttggtgtag ttacataaga tgatggtgga
     3721 agccagcaac attcccagca caatcggtag cttacgtgcc agggtcaggg ataaaccgcg
     3781 tttgatcaga taatccgaga agacacctcc cagcacgccg cccgcaaaac cacacagtgc
     3841 tggaatcgag gcgaccagac ccactttcag aatcgacatg cctttttcct gcaccagata
     3901 aatcgggaac caggtgagga agaaccaggt gatggtgttg ataaaatatt gtccgaaaaa
     3961 tacgcccagc atcatgcggt tagagagcaa ttgcttgatg taatgcagtt tgggtccgct
     4021 tgctgccgca ctgcccggct ttttgtggtc catatcgacc accgcgccat tttcagagat
     4081 aaacttcagc tcttccgcag acatacgtgg gtgatctgtc gggttatgaa tcaacttgat
     4141 ccacagcgcc gtcagcacaa aaccaatcac ccccataacg gtaaagacgt gctcccagcc
     4201 ccaggcgaaa gtcagccagc caagcagcgg cgaaaagagc gccagcgaga aatattgcgc
     4261 cgagttaaag atggcggagg cagtaccacg ttctttcgtc gggaaccagg cggcgacaat
     4321 tcgggcgttc gccgggaatg atggcgcttc cgagaagccg agcataaagc gcataaagaa
     4381 catggagatc cctgcccagg ccagcgggaa catatcaaca aagccttgca ggaaggtgaa
     4441 tagcgaccag aaaaagaggc tgtaggtgta aacttttttc gagccaaact tatcaagcag
     4501 ccagccgccg gggatttgca tcagcaagta ggcccagcca aaagcggaga agatgtaacc
     4561 catcgaaacc gcacttaact gcaactcttt tgccacttcg gtaccagcaa tagacagcgt
     4621 tgcacgatcg gcgtagttaa cggcggtaac aataaaaata atcagtaata ttaaatagcg
     4681 ggtatgcacg cctttctttt tttcgtcaac ggtgtccaga atcattttat ttacctcggg
     4741 tacttatgct gatttttatt attatgggga aggtgttatt tatgagtttc atttatgccg
     4801 taacgacaat gaactcggga attagtataa gcagcgcgag aataataatc attgtgcaaa
     4861 tgctaattta attaatacta tttaaatatt attttgagca tatgcacata aggttgcgcg
     4921 ctaaagcaca gatttgcgct ttaccttacc gggcggcact gcaatccctg aaatgattga
     4981 cattgatcac atttctgcgt ttaaactcct gacattctta tttcacccaa tgaagtcatt
     5041 tatttttaaa tgagaccagg tcctcatttt aataacccct ggctggagaa tattgcacaa
     5101 tggccaacat cgaaatcaga caagaaacgc caactgcgtt ttatataaaa gttcacgaca
     5161 cagataatgt ggcaattatt gttaatgata atggcctgaa agcaggaacg cgttttccgg
     5221 atgggctgga attaattgaa catattcccc aggggcataa agtcgcattg ctggacattc
     5281 cggctaatgg tgaaattatt cgttatggcg aagtgattgg ttacgccgtg cgtgcaatcc
     5341 cacgcggaag ctggatcgac gaatcaatgg ttgtactacc ggaagcgccg ccgttacaca
     5401 cgctgccact ggcaaccaaa gtcccggaac ccttaccgcc gctggaagga tacacctttg
     5461 agggctatcg caatgacgat ggcagcgtgg gcaccaaaaa cctgctcggt atcaccacca
     5521 gcgtccactg tgtggcaggc gtggtggact atgtagtaaa aatcattgaa cgcgatctgc
     5581 taccgaaata cccgaacgtc gatggcgtgg tggggctgaa tcatttgtac ggttgtggcg
     5641 tggcgattaa cgcaccggcg gcagttgtac ctatccgtac cattcacaat atttcgctga
     5701 atcctaactt tggcggcgaa gtaatggtga ttggcctggg ttgtgaaaag ttgcagcctg
     5761 agcgcctgct gactggaacg gatgatgtgc aagctattcc agtagaaagc gccagcattg
     5821 tcagtttgca ggatgaaaag catgtcggtt ttcagtccat ggtcgaggat attttgcaga
     5881 tcgccgaacg ccatctacaa aaactgaatc aacggcagcg agaaacctgc ccggcttcag
     5941 aactggtcgt tggtatgcag tgcggtggca gcgatgcgtt ttctggtgta acggcaaacc
     6001 cggcggttgg ctatgcgtct gatctactgg tgcgctgcgg cgcaacggtg atgttttcag
     6061 aagtaacgga agtgcgtgac gcgatccatc tgctgacacc acgcgcagtg aacgaagagg
     6121 tcggcaaacg gctgctggag gagatggagt ggtacgataa ctatctcaat atgggaaaaa
     6181 ccgaccgcag cgccaaccct tcgccgggca acaagaaagg cggtctggca aacgtggtag
     6241 agaaggcact cggctccatt gctaaatcgg gtaaaagcgc aattgttgaa gtgctgtcgc
     6301 ccggtcaacg cccgactaaa cgcggattaa tttacgccgc gacgccagcc agcgattttg
     6361 tctgtggcac gcaacaggtg gcttcgggta tcacagtgca agtgtttacg accggtcgtg
     6421 gtacgccgta cggcctgatg gcggtacccg tcattaaaat ggcaacccgc accgagctgg
     6481 cgaaccgctg gtttgattta atggatatta atgcgggcac catcgctacc ggcgaagaaa
     6541 ctattgaaga ggtgggctgg aagttgttcc actttattct cgacgtcgcc agcgggaaga
     6601 agaaaacctt ctcggatcaa tgggggctgc ataaccagct ggcggtgttt aacccggcac
     6661 cggtgacctg atttcttttg gaacgtccct cgcaaaacat ggccttagtg ccatgttttt
     6721 attgtttaaa gcccccacgt ccattaataa tgcatttgca ttaccttagt tcaagcttat
     6781 aatttgagca gaaaacaggc tgtaaaagga cagtgaatca tgcccgctaa tgctcgctct
     6841 cacgctgtac tgaccactga atcaaaggtc acgatacgcg gacaaacaac tatccccgcg
     6901 ccagtgcgtg aggccttaaa actgaagcca ggccaggaca gcattcatta cgaaattctg
     6961 cctggtgggc aagtatttat gtgccgactg ggagatgaac aggaggatca tactatgaat
     7021 gcatttttgc gttttctgga tgcagatatc cagaacaacc cgcaaaaaac tcgtccattc
     7081 aacattcaac aaggaaagaa acttgtcgct ggcatggacg tcaacattga tgatgagatt
     7141 ggcgacgacg aataatggat tttccacaaa gggttaatgg ttgggcgcta tatgctcatc
     7201 cctgttttca ggaaacctac gacgctttag ttgccgaagt cgagacatta aagggaaaag
     7261 atcctgaaaa ttatcagaga aaagccgcca caaagttatt ggcggtagtc cataaagtga
     7321 ttgaggagca tatcacggtc aatccatcat caccggcatt ccgtcatggc aagtcgttag
     7381 gctctgggaa aaataaagac tggtcacggg taaaatttgg tgctggtcgt tatcgtctct
     7441 tctttcgtta tagtgaaaaa gagaaagtca tcattctggg atggatgaac gatgaaaaca
     7501 ctctgcgcac ctacggtaaa aaaacagatg cctataccgt attcagcaaa atgttaaaaa
     7561 gaggacatcc tcctgccgac tgggaaaccc tcacccgaga aacagaagaa acccattgat
     7621 ggtgttcaca atgcccgccg aacgcattcg tgttgaccag cgggcatcct ttctcactcc
     7681 ccgaccagaa tcacttcaac cccagccttt cgcagtcctt ccaggctatc cgcaggaatg
     7741 ccttcatcaa caatgatcat gtcgatacgt tgagtatcaa tgatcttatg taaactggaa
     7801 cgattgaact tactggaatc ggtgaccacg atgatccgtt ccgcaacttc gcacatccga
     7861 cggtttaaac gagcttcatc ttcattatgt gtgctgacgc cgcgctccag atcgatcgca
     7921 tctacaccaa gaaacagcat atcgaagtgg taattttgca gcgattgctc agcctgatcg
     7981 ccgtaaaaag attgcgactg acggcgcaaa tgcccgccag tcatcagcag ctcaacgcct
     8041 tccgcttcca gcaacgcatt agccacgttc ataccgttgg tcatcgcaat tacgtcagtg
     8101 tgcttgcgca tcagacgagc aatctcaaaa gtggtggtcc cggaatcgag gataacccga
     8161 tgacctggct gaatcaactc aacggcagct ttcgcaacgc tgcgtttcat cgcggtgttc
     8221 agtgcgcttt tatcttccac tgatggctcg actgacggcg tcgtgctatc gcagatcaac
     8281 gcgccaccat aggcacgcac agcgatcccc tgcttttcca gaaacgccag atcgttgcgg
     8341 atcgtcacag tagatacgcc atacaatgcc gacagatcgt taacctgcac actcccttgc
     8401 tgtcgcagac gctgaatgat ctgttctcgt cgctcgctgg tgccagtcac tcgcttctca
     8461 cctgaagcgt cggtattact catagtaagt cctttcgtaa aactttcgtt tcatttcgtt
     8521 ttgcctatta acgcctttct attaagcaaa tgcaagccca ccttgcccat tgacgcaagc
     8581 tactctcgtt tcagtgactt tcattatgtt tcttttgtga atcagatcag aaaactatta
     8641 tctttcgttt tatttttatc tcaccatgac gcagtatcaa ctgaaagaaa acgaaagatt
     8701 aatatcgcag taatctgaac tggagaggaa agtgaaacat ctgacagaaa tggtgagaca
     8761 gcacaaagcg ggcaaaacaa atggaattta tgccgtttgt tccgcacatc cgctggtgct
     8821 ggaggctgca atccgctacg ccagtgcaaa ccaaacgccg ttactgattg aagcaacctc
     8881 caatcaggta gaccagttcg gcggttatac cggaatgacg cccgccgatt ttcgcggctt
     8941 tgtttgtcag ctcgccgact cgttgaattt cccgcaggat gcgttgattc tgggtggtga
     9001 ccatctgggg ccaaaccgct ggcaaaacct gccggccgct caggcaatgg ccaatgccga
     9061 tgatttgatt aaaagctacg ttgcggcagg attcaaaaaa atccaccttg attgcagcat
     9121 gtcctgtcag gacgatccga ttcccttaac tgatgacatc gtggctgaac gcgccgcccg
     9181 tctggcgaaa gtggcggaag aaacctgtct tgaacacttt ggcgaagccg atctggagta
     9241 tgtcattggt accgaagtgc cggtacctgg cggcgcgcat gaaaccttaa gcgagctggc
     9301 ggtcaccacg ccggatgccg cccgcgccac gctggaagcc catcgtcacg cctttgaaaa
     9361 gcaaggtttg aatgccatct ggccacgcat cattgccctg gtggttcaac ccggcgtcga
     9421 attcgatcac accaacgtta ttgattatca gcccgccaaa gcgagcgcct taagccagat
     9481 ggtcgaaaac tacgaaacgc tgattttcga agcgcactct accgattatc aaacgccgca
     9541 atcgctgcgc cagctggtga ttgaccactt tgccattctg aaagttggcc cagcgctgac
     9601 cttcgccctg cgtgaagctc tgttctctct ggcggcgatt gaagaagaac tggtgccagc
     9661 gaaagcctgt tctggtctgc gtcaggtgct ggaagacgtg atgctcgacc gcccggaata
     9721 ctggcaaagc cactaccacg gtgacggcaa cgcgcgtcgt ctggcgcgtg gttatagcta
     9781 ctcggatcgc gtgcgctatt actggccgga cagccagatt gatgacgctt tcgctcatct
     9841 ggtacgtaat ctggcggatt caccaattcc gctgccgctg atcagccagt atctgccgct
     9901 gcagtacgtg aaagttcgct ccggcgagct gcagccaacg ccacgggaac tcattatcaa
     9961 ccatattcag gacatcctgg cgcagtacca cacagcctgt gaaggccaat aagcaaaaca
    10021 aagaggaaca cgctatgcca aatattgttt taagccggat tgatgaacgc ttgattcacg
    10081 gtcaggtcgg cgttcaatgg gtcggatttg cgggggcaaa tctggtgctg gtagccaacg
    10141 atgaggttgc cgaagatccg gtacaacaaa acctgatgga aatggtactg gcagaaggga
    10201 tcgccgtacg tttctggacg ctgcaaaaag ttatcgacaa cattcatcgc gccgccgatc
    10261 gacagaaaat cctgctggtt tgtaaaacac ccgccgattt cctgacgctg gtgaaaggtg
    10321 gcgttccggt gaatcgcatt aacgttggca atatgcacta cgccaatggc aaacaacaaa
    10381 tcgccaaaac ggtttctgtg gatgcgggcg atatcgcagc atttaacgac ctgaaaaccg
    10441 ctggggtgga atgcttcgtt cagggcgtcc cgacagagcc tgctgtggac ctctttaaat
    10501 tactttgagg gattcatcat ggaaatcagc ctgttgcagg catttgcgtt gggcattatc
    10561 gcctttatcg ctggcctgga tatgtttaac ggcctaaccc atatgcaccg cccggtggtc
    10621 ctcggcccgt tggtcgggct ggtacttggc gatctgcata ccggaatttt aaccggcggt
    10681 acgctggaac tggtgtggat ggggctggcc ccgctggcgg gcgcacagcc gcctaacgtg
    10741 attatcggta ctatcgtcgg cacggcgttt gccattacta ctggcgtgaa acccgatgtc
    10801 gcagtaggtg tcgccgtacc tttcgctgtc gcagtacaga tggggattac cttcctgttc
    10861 tcggtgatgt ccggcgtgat gtctcgctgc gaccggatgg cggagaacgc cgatactcgc
    10921 ggcattgaac gcgtgaacta tctggcactg ctggcactcg gcattttcta ttttctctgc
    10981 gctttcctgc ctatctactt cggcgcggaa catgcaaaaa ccatcattga tgtcctgccg
    11041 caacgattaa tcgacggcct cggcgtcgcg ggcggcatca tgccagcaat cggttttgcc
    11101 gtgctgctga aaatcatgat gaaaaacgtc tacatcccct acttcatcct gggctttgtt
    11161 gccgccgcct ggctcaagtt accagtgctg gctattgctg ccgctgcgct ggcgatggcg
    11221 ctgatcgact tgctgcgtaa atctcctgaa ccgactcaac ctgcggcaca gaaagaggaa
    11281 tttgaagatg gcatctaatc aaaccaccct gccgaacgtc agtgaaaacg aagaaacatt
    11341 gctgactggc gtcaatgaaa acgtgtatga agatcagagc attggcgcgg agctgacgaa
    11401 aaaagatatc aaccgcgtcg cctggcgttc catgctgtta caagcgtctt ttaactacga
    11461 acgtatgcag gcttctggct ggttgtacgg tctgctgcct gctctgaaaa agatccacac
    11521 taataaacgc gacctggcgc gcgccatgaa ggggcatatg ggtttcttca atacccatcc
    11581 gtttctggtg acgtttgtta tcggcattat ccttgcgatg gagcgttcta agcaggacgt
    11641 taacagtatt cagagcacca aaattgccgt cggtgcgccg cttggcggga ttggcgatgc
    11701 aatgttctgg ctaacgctac tgccgatttg tggcgggatt ggagccagtc tggcattgca
    11761 aggctccatt cttggcgcag tcgtctttat tgtgctgttc aacgtggtac acctggggct
    11821 gcgttttggt ctggcgcatt atgcttaccg catgggcgtg gcggcgattc cactgattaa
    11881 agcgaatacc aaaaaagtcg gccatgctgc gtctatcgtt gggatgacgg taatcggtgc
    11941 gctggtggca acctatgttc gtttaagcac cacgctggaa atcacggcgg gcgacgcagt
    12001 ggttaagtta caggctgatg ttatcgacaa actgatgccg gccttcttac cgttggtcta
    12061 caccctgacc atgttttggt tggtacgccg cggctggagt ccgctgcgtc tgattgcagt
    12121 taccgtggtt ctcggcatcg tcggtaaatt ctgtcatttc ctttaaatac aatgaggtat
    12181 tagatgttaa gtattatttt gacagggcat ggcgggtttg ccagcggcat ggaaaaagca
    12241 atgaagcaaa ttctcggtga gcaatcgcag tttatcgcca tcgattttcc ggaaacctca
    12301 agcaccgcgc tgcttacatc gcagcttgaa gaggccatcg cccaactgga ttgtgaagac
    12361 ggcattgttt ttctgacgga tttgctgggc ggcacgccgt ttcgcgtagc ttcaacgctg
    12421 gcgatgcaaa aaccgggctg tgaagtgatc accggcacca atttgcaact gctactggag
    12481 atggtgctgg agcgcgaagg gttaagcggt gaagaattcc gtgtacaggc gctggagtgt
    12541 ggacaccgag ggctgaccag tctggtggac gagttaggcc gctgccatga agaatgtccg
    12601 gtcgaggaag gaatatgaca cacgttctgc gcgccagaag gctgctgact gaagagggat
    12661 ggctcgatga ccatcagttg cgtattgctg acggtgtcat cgcagcaatc gaaccgattc
    12721 cagcgggcgt gactgaacgc gatgcggaac tgctctgccc tgcttacatc gacacccatg
    12781 tacacggtgg tgcgggcgtt gatgtaatgg atgacgcgcc ggatgtactc gacaagctgg
    12841 caatgcacaa ggcacgcgaa ggtgtcggca gttggttacc gaccaccgta accacgccgc
    12901 ttaataccat tcatgcggcg ctgaaacgta ttgctcaacg ttgccaacgc ggcggacctg
    12961 gtgcgcaagt gctggggagt tatctcgaag gaccgtactt cacgccgcag aataaaggcg
    13021 cgcatccgcc ggagttgttt cgcgagcttg aaattgccga gctggatcag ttgattgccg
    13081 tttctcagca caccttacgt gtggtagcgc tggcaccgga aaaagaaggg gcattgcagg
    13141 ccatccgcca tcttaaacag caaaacgtaa gggtgatgct ggggcatagc gcggcgacct
    13201 ggcaacaaac ccgcgccgca tttgatgctg gtgccgacgg cctggtgcat tgctataacg
    13261 ggatgacagg tttacatcac cgcgaaccgg gaatggttgg cgcgggatta acggacaagc
    13321 gcgcctggct ggaactgata gccgatggtc atcatgtgca tccggcggca atgtcgctgt
    13381 gttgttgctg tgcgaaagag agaatcgtac tgatcaccga cgcgatgcag gcagctggga
    13441 tgccggatgg tcgctatacg ttatgtggtg aagaagtgca gatgcacggt ggcgttgtcc
    13501 gtaccgcgtc tggtgggctg gcgggcagta cgctgtctgt tgatgcggca gtgcgcaata
    13561 tggtcgagtt gacgggcgta acgcctgcgg aagccatcca tatggcgtcg ctgcatccgg
    13621 cgcgaatgct gggtgttgat ggtgttctgg gatcgcttaa accgggcaaa cgcgccagcg
    13681 tcgttgcgct ggatagcggg ctacatgtgc aacaaatctg gattcagggt caattagctt
    13741 cgttttgata gtttgctcct ttattgggcc ttcacttccc ccgtaaggcc tttctttttc
    13801 tttcgttttg atctgtgcag cggtgtcgga tgcgacgcta acgcgtctta tccgacctac
    13861 agttggtgac cgcaaggccg gataaagcgt ttgcgccgca tccagcaatc ccttttgctt
    13921 cctttatctt ttctttcaac gatcacaaat ttcgttttat ttcttttttc tccattgaac
    13981 tttcagtttc ttttctatag attttaatca acgaaagaca tcaccaagtg aaatgaaacg
    14041 aaaggcaagt gaaagcgaca acgcccgacg tcaagttcat cagactaagg attgagttat
    14101 gccagaaaat tacacccctg ctgccgccgc aaccggtaca tggactgaag aagagatccg
    14161 ccatcagcct cgcgcatgga tccgttcact caccaacatc gacgcgctac gttccgcgct
    14221 caataacttc cttgaaccgt tactgcgcaa agagaatctg cggatcatcc tgaccggagc
    14281 cggaacgtcg gcatttatcg gtgacatcat cgcgccgtgg ctcgccagcc ataccggtaa
    14341 aaacttcagc gccgtaccga ccaccgatct ggtcaccaat ccgatggact acctgaaccc
    14401 agctcatccg ctgctgttga tctccttcgg tcgatccggc aacagcccgg aaagcgtcgc
    14461 agccgtggaa ctggcaaatc aatttgtacc ggaatgctat cacctgccga tcacctgcaa
    14521 cgaagcgggc gctctttacc aaaacgcgat caacagcgat aacgcgtttg ccctgctgat
    14581 gcccgcagaa acgcacgatc gcggctttgc gatgaccagc agcattacca ccatgatggc
    14641 cagctgcctc gcggttttcg cacctgagac gatcaacagc caaaccttcc gcgacgtggc
    14701 ggatcgttgc caggcgatcc tgacctcact gggcgatttc agcgaaggtg tgtttggtta
    14761 cgcaccgtgg aaacggatcg tttatctcgg tagcggtggc ttacagggcg cagcacgcga
    14821 gtcggcgctg aaagtgctgg aactgacggc gggtaaactg gcggcctttt atgattctcc
    14881 aaccggattc cgtcatggac caaaatcgct ggtcgatgac gaaacgctgg tggtggtatt
    14941 tgtctccagc cacccttaca cccgtcagta tgatcttgat ctgctggctg aacttcgccg
    15001 tgacaaccag gcaatgcgtg taatcgccat cgccgcggaa agcagcgaca tcgtcgctgc
    15061 cggtccacat atcatcctgc caccgtcacg tcactttatc gacgttgagc aggcattttg
    15121 cttcctgatg tacgcccaga cgtttgcact gatgcagtcg ctgcacatgg gcaatacgcc
    15181 ggatacccca tcagccagtg gcaccgttaa ccgcgtggtg caaggcgtaa tcattcatcc
    15241 gtggcaggca taagaggatc gcattatgag cattatctcc actaaatatc tgttacagga
    15301 cgcccaggcc aatggctacg cggtgcctgc ttttaacatt cataacgccg agacgatcca
    15361 agcgatcctc gaagtgtgca gtgaaatgcg atcgccggtg atcctcgccg gaacgccggg
    15421 gacctttaaa cacatcgcgc tggaagagat ctacgccctg tgtagcgcct attccacaac
    15481 ctacaacatg ccactggcgc tgcatctcga ccaccacgaa tcgctggatg atattcgccg
    15541 taaagtccac gcaggtgtgc gcagtgcgat gatcgacggc agccacttcc cgtttgccga
    15601 gaacgtgaag ctggtgaaat cggttgttga cttctgccac tcacaagatt gcagcgtgga
    15661 agcagaactg ggccgcctgg gcggtgttga agatgacatg agcgttgacg ccgaaagtgc
    15721 attcctgacc gatccacaag aagctaaacg ctttgtcgaa ctgactggcg tcgacagcct
    15781 ggcggtagcg attggtacgg cgcacggctt atacagcaaa acgccgaaga ttgatttcca
    15841 gcggctggcg gaaattcgtg aagtggtgga tgttcctctg gtgctgcatg gtgccagcga
    15901 tgttccggat gaatttgtcc gtcgcactat tgaacttggc gtcacaaaag tgaacgttgc
    15961 cacagaatta aaaatagcct tcgctggcgc ggttaaagcc tggtttgcgg aaaatccgca
    16021 gggtaatgat cctcgttatt atatgcgcgt cggaatggat gcgatgaaag aagttgtcag
    16081 aaataaaatt aatgtctgtg gttcagcgaa tcgaatttca gcataatcat tagtttttta
    16141 tgatttatcc caatgtactt cccgattaat atcggggagt gccttaatgg aaaaggagat
    16201 aactaaacct taata
//
LOCUS       DAPHKZ010000101        16186 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.101, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000101 DAPHKZ010000000
VERSION     DAPHKZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16186
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.101"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(262..687)
                     /gene="arsC"
                     /locus_tag="RH288_003384"
     CDS             complement(262..687)
                     /gene="arsC"
                     /locus_tag="RH288_003384"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-dependent arsenate reductase"
                     /protein_id="HDV4032413.1"
                     /translation="MSNITIYHNPACGTSRNTLEMIRNSGTEPTIIHYLETPPTRDEL
                     VKLIADMGISVRALLRKNVEPYEELGLAEDKFTDDRLIDFMLQHPILINRPIVVTPLG
                     TRLCRPSEVVLEILPDAQKGAFSKEDGEKVVDEAGKRLK"
     gene            complement(700..1989)
                     /gene="arsB"
                     /locus_tag="RH288_003385"
     CDS             complement(700..1989)
                     /gene="arsB"
                     /locus_tag="RH288_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite/antimonite:H(+) antiporter ArsB"
                     /protein_id="HDV4032414.1"
                     /translation="MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPG
                     DIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLG
                     AAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
                     NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAI
                     KDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLR
                     GAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSI
                     MNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQ
                     KNMTISWGYYFRTGIIMTLPVLFVTLAALALRLSFTL"
     gene            complement(2043..2396)
                     /gene="arsR"
                     /locus_tag="RH288_003386"
     CDS             complement(2043..2396)
                     /gene="arsR"
                     /locus_tag="RH288_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /protein_id="HDV4032415.1"
                     /translation="MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQ
                     PKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAKIIDEAWRCEQEKVQAIVRN
                     LARQNCSGDSKNICS"
     gene            3136..3219
                     /locus_tag="RH288_003387"
     CDS             3136..3219
                     /locus_tag="RH288_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Damage inducible protein"
                     /protein_id="HDV4032416.1"
                     /translation="MIDKAIIVLGALIALLELIRFLLQLLN"
     gene            complement(3273..4625)
                     /gene="gorA"
                     /locus_tag="RH288_003388"
     CDS             complement(3273..4625)
                     /gene="gorA"
                     /locus_tag="RH288_003388"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDV4032417.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENV
                     LGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
                     FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTNAIPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAG
                     VKTNEKGYIVVDKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCVGSEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
                     "
     gene            complement(4697..5539)
                     /gene="rlmJ"
                     /locus_tag="RH288_003389"
     CDS             complement(4697..5539)
                     /gene="rlmJ"
                     /locus_tag="RH288_003389"
                     /EC_number="2.1.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase"
                     /protein_id="HDV4032418.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPL
                     IARLLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGIAEGYKRFATGIYALWYPVVLRQQIKRMIHDLEATGIRK
                     ILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSW
                     IVPE"
     gene            5742..7784
                     /gene="prlC"
                     /locus_tag="RH288_003390"
     CDS             5742..7784
                     /gene="prlC"
                     /locus_tag="RH288_003390"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HDV4032419.1"
                     /translation="MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQG
                     APYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFE
                     NYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVR
                     FFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFR
                     PDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     FSRFEEEGIFNRETGQSFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIKG"
     gene            7792..8544
                     /gene="rsmJ"
                     /locus_tag="RH288_003391"
     CDS             7792..8544
                     /gene="rsmJ"
                     /locus_tag="RH288_003391"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HDV4032420.1"
                     /translation="MKICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTD
                     ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVK
                     RPDYAPPLANVATPNAVVTKGHRFDIYAGTPV"
     gene            complement(8593..10062)
                     /gene="dtpB"
                     /locus_tag="RH288_003392"
     CDS             complement(8593..10062)
                     /gene="dtpB"
                     /locus_tag="RH288_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HDV4032421.1"
                     /translation="MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQ
                     LGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSL
                     LKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIAL
                     SLAPVIADRFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFRPMSFSKLLYVL
                     LGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLML
                     EAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYT
                     HLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLG
                     ELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLET
                     LPVYTNVFGKIGLVTQGVAVVMLLMVPWLKRMIATPESH"
     gene            complement(10379..10813)
                     /gene="uspA"
                     /locus_tag="RH288_003393"
     CDS             complement(10379..10813)
                     /gene="uspA"
                     /locus_tag="RH288_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HDV4032422.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            11204..11539
                     /gene="uspB"
                     /locus_tag="RH288_003394"
     CDS             11204..11539
                     /gene="uspB"
                     /locus_tag="RH288_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HDV4032423.1"
                     /translation="MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYV
                     DGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVV
                     SLIALMIWH"
     gene            complement(11783..13282)
                     /gene="pitA"
                     /locus_tag="RH288_003395"
     CDS             complement(11783..13282)
                     /gene="pitA"
                     /locus_tag="RH288_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HDV4032424.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
                     VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQ
                     HPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSL
                     DQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVL
                     SSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL"
     gene            13514..14716
                     /locus_tag="RH288_003396"
     CDS             13514..14716
                     /locus_tag="RH288_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDV4032425.1"
                     /translation="MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGIAWHEKTLGQLF
                     CDDSAQQIVDMLVDECEKGNVTFRLRSEVLSVAKDETGFTLDLNGMTVGCEKLVIATG
                     GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITA
                     ENGTVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPN
                     QSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQALISTLTDWRVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLIAAKSS"
     gene            complement(15031..16083)
                     /locus_tag="RH288_003397"
     CDS             complement(15031..16083)
                     /locus_tag="RH288_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 domain-containing protein"
                     /protein_id="HDV4032426.1"
                     /translation="MNIYIGWLFKLIPLIMGLICIALGGFVLESSGQSEYFVAGHVLI
                     SLAAICLALFTTAFIIISQLTRGVNTFYNTLFPIIGYAGSIITMIWGWALLAGNDVMA
                     DEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNAAGSKSDGTPVQAYSSLIGNCLI
                     AVPVLLTLLGFIWSITLLRSADITPHYVAGHVLLGLTAICACLIGLVATIVHQTRNTF
                     STKEHWLWCYWVIFLGSITVLQGIYVLVSSDASARLAPGIILICLGMICYSIFSKVWL
                     LALVWRRTCSLANRIPMIPVFTCLFCLFLASFLAEMAQTDMGYFIPSRVLVGLGAVCF
                     TLFSIVSILEAGSAKK"
BASE COUNT         4160 a         4131 c         4193 g         3702 t
ORIGIN      
        1 cgtctttaaa ctactgcgct gtatcgctga taactaagca gctcactgat acaccatgct
       61 ggacgcgata attggaatct cacgcaggga gtactgtgta aatagcaaaa tcgcctgatg
      121 cgctacgcct gtcaggccta caaataacat actattcatc gaattttcat aactttgtag
      181 gtcggataag acgcgccagc gtcgcatccg acataaataa agcgcacttt tctaacaacc
      241 tgtggggggg atatcgccgc tttatttcag gcgcttaccc gcttcatcaa ccactttctc
      301 gccatcttcc ttggagaatg cgcctttttg cgcatctggc agaatttcca gcaccacttc
      361 tgaagggcgg cacaggcgag ttcccagcgg cgtcaccaca atcgggcgat taatcagaat
      421 cgggtgctga agcataaagt cgattaaccg atcgtcagta aatttatctt ccgcaaggcc
      481 cagctcctca tacggttcga cgtttttacg cagcagcgcg cgtacggaaa tccccatatc
      541 ggcaatgagt ttgaccagtt catcgcgcgt tggcggagtt tccagataat ggataatggt
      601 cggttctgtg ccgctgttgc ggatcatctc cagcgtatta cgcgacgtgc cgcaggccgg
      661 gttgtgataa atggtaatgt tgctcatatc agtatctcat tacaaagtga aagagagacg
      721 tagcgccagc gcagccagcg tcacaaacag cacaggcagg gtcatgataa tccctgtacg
      781 gaagtaatat ccccagctga tagtcatatt cttctgcgaa agtacgtgca gccagagtag
      841 cgtagccagg ctaccaattg gggtaatttt cggtcccaaa tcgcagccaa tcacattggc
      901 ataaaccatc gcttctttga taacgccaga tgccgtgctg ccatcaatgg acaacgcgcc
      961 aaccagtacc gtcggcatat tgttcataat agaagagagg aaggcggtga ggaatccggt
     1021 gccgagcgtc gcggcccaca ggccgttatc cgccagcacg ttgagtacgc cagaaagata
     1081 ttccgttaat ccggcattgc gcaggccata aaccaccaga tacatgccga gcgagaagat
     1141 gacaatctgc cagggggcac cgcgcaggac tttacccgta ttaatcgcat gaccgcgttt
     1201 agcgacgaca aataatatca gcgcgcccac agctgcaatg gcgctcaccg gaatgccgag
     1261 cggttccagg acgaaaaatc ccaccagcag aagcagtaaa acaacccagc cagttttgaa
     1321 cgtagcagga tctttgatcg cttctgcggg agatttcagc agcgccatat cgtagttctg
     1381 cggaatatct ttgcgaaaat agagatgtaa catcaccagc gtggcaacaa tcgcggcgat
     1441 atccaccggc accatcaccg aggcgtattc gcgaaagccg aggccaaaga aatcagcgga
     1501 tacgatattc accaggttgg agacaataag cggcaggctg gcggtatcgg caatgaatcc
     1561 ggccgccatc acgaacgcca gcgtagtgcc tttactgaac cctaaagcca gcagcatggc
     1621 gatgacaatc ggtgtcaaaa taagcgccgc gccatcattg gcaaacaggg cggcaacggc
     1681 agcaccgagc aggacaatcc aggtaaacag caagcgacca cgaccattac cccagcgtga
     1741 gacgtgcagc gccgcccatt caaaaaagcc ggactcatcc agcagcaggc tgatgataat
     1801 gacggcgata aacgcagccg tcgcgttcca gacgatattc cacaccaccg gaatatcacc
     1861 cggatggacc acgcccgtaa ctaacgccag tactgcgccg agcgttgcac tccagccgat
     1921 gcctaaacct ttcggctgcc agataaccaa tacgatggtc aggacaaaga tagcgcctgc
     1981 cagtaacata atgcctcccg gataaaacac atctgaaaat tcatatgtgt ttagctaaat
     2041 ttttaactgc aaatgttctt actgtccccg gaacagtttt gtcgagccag gttgcggaca
     2101 atcgcctgaa ccttttcctg ttcacatcgc caggcctcat caataatttt cgccgcccat
     2161 gctggaatat gcggtgataa gcggtaatga acccacttac cttgcttgcg gtccagcaat
     2221 agcccgcttt cacgcagcaa tgccaggtgg cgggagatct tgggctgcga ctggtcgaga
     2281 gcagtgcaga gatcgcagac gcataactct cccagttcgc tgagcagtaa aacgatgccc
     2341 agacgggttt catcagcaag aattttgaac aattggatgg gtaacagaaa tgacatattg
     2401 cgctcctgat tgttgcaggt agtgtctctc ttcgaagcgg ataagtcaaa aacatatatg
     2461 acttaacgaa tgtgtaagtg cagaggaagg taataggtgt gaattttgag ttggctattc
     2521 atttgaaagg aggtctgaat caggacgtaa aaaaaccgac tttgcgtcgg ttttttactt
     2581 tccagccctg agttggtggc tctggctgga gtgagagagt tcttatctaa cagctcaata
     2641 ctattagcca gtggctaaca ttgcaagaat tagcgatttc ttcagctggc ggagggagca
     2701 cttcggtata tatcgcagtg acgatttata tactttcact gggtcatcgt catattaagc
     2761 cttgtccgaa tccggatgta aaaaaaccga ctttgcgtcg gttttttact ttccagccct
     2821 gagttggtgg ctctgactgg agtgagatag ccatcatcta acgcatcaat gctaatacca
     2881 tactgaaact attgcaagga cgtgctggtt ttataacctg catgtactgt atgattatcc
     2941 agttagctct gaggcatttt cactctggca atgcgcataa acgctttcaa agtcctggtc
     3001 agaagtacgg gtggtgccgt taactgatgc tctggccgga gtgagagagt tcttatctaa
     3061 caatgagaca tgcgccgtga caggcagtgg atgagtaagc ggatgcattc tcactccatc
     3121 gcatggagaa aacgggtgat tgataaagca atcatcgttc taggggcgtt aattgcgctg
     3181 ctggaactga tccgctttct gcttcagctt ctgaactgat agcggaaacg taattaaggg
     3241 ctaagagcac actactctta gccctttaac atttaacgca ttgtcacgaa ctcttctgcc
     3301 gccgttgggt gaatggcgac ggtattgtcg aagtcttttt tggttgcccc catcttcagc
     3361 gccaccgcga agccctgcaa catttcgtcc ataccaaagc caatgccgtg aataccgaca
     3421 atcttctctt ccgatccaac gcacaccagc ttcatgcggc acggctggcg gtgagtggtg
     3481 acggcggtat acatcgcggt gaaagaggat ttatacactt tcacctgatc gtcgccatac
     3541 tgctcgcgcg cctgcggttc cgttaaacca acagtaccaa tcggcggatg gctgaagacc
     3601 acggtcggaa tgttgctgta atccagatgc tcatccggct tgttattaaa caggcgttca
     3661 gagagacggc gacccgctgc aactgccacc ggtgtcagct ccactgcacc cgtgttatcg
     3721 cccaccgcgt aaataccttc aatattggtg ttttgatatt tatcgacgac gatatagcct
     3781 ttttcgttag ttttaacgcc agcggcttcc aggttgatgt tgtcattggc aggctcgcga
     3841 ccaatcgccc aaatcaggca atccaccgtt tcactgcgac catcttccag ctccagcgtc
     3901 aggctaccat cggcattttt cactaccgct ttcgggatgg cgttggtgtg cagctgcggg
     3961 ccttcggcgt tcatcacttc gaccagcgtt tcggaaatca tcgggtcgaa gctgcgcagc
     4021 ggcgcatgtt tacgcacaaa cagatgcgtt ttcgcgccga ggccgttaat cacgcccgcc
     4081 agctcaacgg cgatgtaacc cgcgccaaca accgccacgc gctctggcaa agcaggaagg
     4141 gcgaagaagc catcagaatc aataccgtat tccacgcccg gaatatccgg gtggctcgga
     4201 cgaccgcctg tggcgatcag aatatgatcg gccgtgatgg tttcgccgtt tacctccagc
     4261 gttttggcat caacgaagcg ggcaaagcct ttgattacat caacgttatt tttaccgagc
     4321 acgttttcat aggaagtatg aatacggtcg atataggcgg tacggctggc gatcaacgtt
     4381 tcccagttga atttattgat agtggtatca aaaccataat ccgggccgta catatggatc
     4441 gcttcacgga tttgcgccgc gtgccacatc acttttttcg gcacacagcc aacatttacg
     4501 caggtgccgc ccagctcttt ggcttcaatc agcgcacatt tctggccgta catagccgcg
     4561 cggttgatgg aggcgatacc gccgctgccg ccgccgatgg cgatgtaatc atagtgttta
     4621 gtcatgacaa agtgtcctta tcgttgatta ccgcgattgt agcgcgagac gtaataggtg
     4681 ccagcaatgg ctgcaattac tccggcacga tccagcttac ggtggcgtgc ccggtgcctg
     4741 ccggaaccag tttgctgtgc agccacggca gcacgttatt catctgttgt tccagtttcc
     4801 acggcgggtt aatcacaatc atgccggaag cggtcatgcc acggcgatcg ctgtctggca
     4861 gtaccgccag ttcaatttgc agaattttgc gaataccggt cgcttccaga tcgtggatca
     4921 tgcgcttaat ttgctgacgc agcaccaccg gataccacag tgcgtaaata ccagtggcga
     4981 aacgtttgta accttctgct atcccgctga ccaccgcttg atagtcagtt ttcatttcat
     5041 acggcgggtc gataaggatt aaaccacggc gggaaaccgg cggcagtttg gccttaagct
     5101 gctggaaacc gtcggctttt tcgacacgcg cacggctatc tttctgaaat tcagaacgca
     5161 acaacgggta atcgctcggg tgcagttcgg tcagttgcag gctgtcctgt tcacgcagta
     5221 gcaggcgagc aatcaacggc gaaccggggt agtaacgcaa ctgaccgcta cggttgaagt
     5281 gttttaccac attgatgtac gcctccagtt ctgcgggcaa atcgtcctgc tgccagatac
     5341 gggcgatgcc ttcgagatat tcgccggtac gctcggcatg ttcgctgcct aactgataac
     5401 gcccggcccc tgcgtgggtg tcgagataga gaaacggttt atctttctct ttcagcgact
     5461 cgatgatcag gctctgaacg gtatgtttaa ggacgtcggc gtggttgcca gcgtgaaagc
     5521 tgtggcgata actgagcatg ggtaaaggtg ttccggtaag taaaaatcgg cccgtattcg
     5581 gggcgcacaa aagcgtatca ggacagtata ccgaaaagag gccgccgccg cgaaagcgta
     5641 acgtttctca ttgaaattca ctacacttaa ccccatgcta cacacattat gtaaagcgcc
     5701 tgttgagcgc ttccttaacc tctttaacca ggactgcgcg aatgacgaat ccgttactga
     5761 ctccctttga attgcctccg ttttctaaaa ttctcccgga acatgtcgtt ccagccgtga
     5821 ctaaggcatt gaacgactgc cgcgaaaacg tggagcgcgt agtagcgcaa ggggcaccgt
     5881 acacctggga aaatctctgc cagccgctgg cggaagtgga cgatgtgttg gggcgtatct
     5941 tctccccggt cagccacctg aactcggtga aaaatagccc ggaactgcgt gaagcctacg
     6001 aacaaaccct gccgctgctg tcggaataca gcacctgggt agggcaacat gaagggctgt
     6061 ataaagcgta tcgcgacctg cgcgatggcg atcattacgc cacgctgaac acggcgcaga
     6121 agaaagcggt tgataacgca ctgcgcgact ttgaactctc tggcataggt ctgccgaaag
     6181 agaaacagca gcgttacggc gaaattgcga cccgtctttc tgaactgggc aaccagtaca
     6241 gcaacaacgt cctcgatgcg acaatgggct ggaccaaact cgttaccgac gaagcggagc
     6301 tggcggggat gccagaaagc gcgctggctg cggcaaaagc ccaggccgaa gcgaaagagc
     6361 tggaaggtta tttgctgacg ctggatatcc caagctactt gccggtaatg acctactgcg
     6421 acaaccaggc tctgcgtgaa gagatgtatc gcgcttacag cacccgcgcc tccgatcaag
     6481 gcccaaacgc cggtaaatgg gataacagca aggtgatgga agagatcctc gcgctgcgtc
     6541 acgaactggc gcaactgctg ggctttgaaa actacgcctt taaatccctt gccactaaaa
     6601 tggcagaaaa cccgcagcag gtgctggatt tcttaaccga tctggcaaaa cgcgcgcgtc
     6661 cacaaggcga aaaagagctg gcgcaattgc gtgcctttgc caaagccgaa tttggcgtcg
     6721 atgagttgca gccgtgggat atcgcttact acagcgaaaa acaaaaacag cacctctaca
     6781 gcatcagtga cgaacagctg cgtccgtact tcccggaaaa caaagcggtt aacggcctgt
     6841 ttgaagtggt taagcgtatt tacggcatca ccgctaaaga gcgtaaagat gttgatgtct
     6901 ggcatccgga tgtacgtttc ttcgaactgt atgacgaaaa taacgaactg cgcggtagct
     6961 tctacctcga tctgtatgcc cgtgaaaaca agcgcggcgg ggcgtggatg gatgactgcg
     7021 taggccagat gcgtaaagct gatggttctt tgcaaaaacc ggtcgcgtat ttgacttgta
     7081 acttcaaccg cccggtaaat ggtaaaccgg cgctgttcac tcacgacgaa gtgatcaccc
     7141 tcttccacga gttcggtcac ggcctgcacc atatgctgac ccgcatcgaa accgctggtg
     7201 tttccggtat cagcggtgtg ccgtgggatg cggtcgaact gccgagtcag tttatggaaa
     7261 actggtgctg ggagccggag gcgctggcgt ttatctctgg tcactatgaa accggcgaac
     7321 cgctgccgaa agagttgctg gataaaatgc tggcggcgaa gaactaccag gcggcgctgt
     7381 ttattctgcg tcagctggag ttcggcctgt ttgatttccg ccttcatgcc gagttccgcc
     7441 cggatcaggg ggcaaaaatc ctcgaaactc tggcagaaat caagaaactg gttgccgtgg
     7501 tgccatctcc gtcctggggc cgtttcccgc acgctttcag ccatattttc gccggtggtt
     7561 atgccgcagg ttactacagc tacctgtggg ctgacgtact ggcggcagat gctttctcgc
     7621 gctttgagga agagggcatt ttcaaccgtg aaaccgggca gtcgttcctc gacaacattc
     7681 tgagccgtgg cggttcagaa gagccgatgg atctgttcaa acgcttccgt ggtcgtgaac
     7741 cgcagctgga tgcgatgctg gagcattacg gcattaaggg ctgatcattc agtgaaaatc
     7801 tgcttaattg atgaaacagg caccggagac ggtgccttat ctgttctggc ggcccgctgg
     7861 gggctggagc acgatgaaga caacctgatg gcgctggtgt taacgccgga acatctggaa
     7921 ttgcgcaagc gtgatgagcc aaaacttggc ggcatctttg ttgattttgt tggcggagcg
     7981 atggcgcacc gacgcaaatt cggcggtggt cgcggtgagg cggtggcgaa agcggtgggc
     8041 attaaaggcg attatttgcc ggatgtggtg gatgccactg caggacttgg gcgcgatgcc
     8101 tttgtactgg cttcagtcgg ctgccgcgtg cggatgctgg agcgtaatcc agtggttgcc
     8161 gcgctactcg acgacggcct ggcgcgtggt tatgcggatg cggaaatcgg cggctggttg
     8221 caggagcggt tgcagttaat tcacgcctcc agcctgacgg cgctgactga tattaccccg
     8281 cgcccgcagg tggtttatct cgacccgatg ttcccgcata agcagaaaag cgcgctagtg
     8341 aaaaaagaga tgcgtgtctt tcagtcgctg gtgggaccgg atcttgatgc cgatggatta
     8401 ctggagcctg cacgcttgct ggcgaccaaa cgcgtggtgg taaagcgccc ggactacgcg
     8461 ccaccgctgg cgaatgtcgc cacgccaaac gcggtagtca ctaaagggca tcgctttgat
     8521 atctatgcag gtacgccagt gtaaaactaa aacagggtag cgataacgct accctgcttt
     8581 ctgcaagaat aattaatggc tttccggcgt cgcaatcatg cgtttcagcc acggcaccat
     8641 caacagcatc actactgcaa cgccctgcgt gaccagacca atcttaccaa acacgttggt
     8701 atagacgggc aacgtctcaa gcggatcggt aatgttgtcc ggcaccgcgg taaatgttgc
     8761 cacatagccg cccagcaaga acgcggcagc ctgcgtcagg aaccacatcc cgagaataaa
     8821 gcccatcaaa tgctgcggca ccagggcagc aatcatcgcc aggccaaggg cgctaataaa
     8881 cagttcacct aagctctgga ataagtacac cagcacgata aaccatggcg atgtcagccc
     8941 ttgtgcatcc gcaaaccaca ttcccgcagc tgccgccgtc aaaaagccca gtgagcacat
     9001 aaacatgccg agagtaaatt tcatcggcat cgagaggtct ttgcctttgt tacccagatg
     9061 cgtgtaaatg cctgccagta ttgggctggc gagtaccacc cagaacgggt taagcgcctg
     9121 gaagctgacc gggttgatgg aaaaaccgag aatttcatga tgcacgttgt tgatggcaaa
     9181 gaagttcagc gatgttggca tctgggcgta gagaatgtaa aacaccaccg cttcgagcat
     9241 caggacaaag gcgacaaaca ttttattgcg cccggtttta tccagcttga atgcctgacg
     9301 aaagaagatg atggtgacga cgatggagag aacaatcagc accagattgg cgacttctac
     9361 gttgtgcatc agccatgcgc atacgaagat catcaccacg ctgccaagta acacgtacaa
     9421 cagtttgctg aagctcattg gccggaagtc gggttcagaa ccaatgtctt tcaccattcc
     9481 acgacaggcg atgtaaacca gtaatgcgat aattaacccc gccccgcaca ggttgtaggt
     9541 gactgaataa ccgaatctat cagcgatcac aggggccagc gataacgcta tcaacgagcc
     9601 gatgttgatc gacatataga acagggtgaa tgcgccatca agccgcggat ctttcggcgg
     9661 atagcacttc gaaagcaagc tggctgggtt agctttaaac aggccgttac cgacagcgat
     9721 agtccccagg gcgatgaaaa tcaggtcagg cttaagtagc gacatgccgg tcatgaagta
     9781 gccaatcgcc agcacaagtg ctccaagaac aatggtgcgt ttggtcccca gcaggtggtc
     9841 gccgacatag ccgccaatgg aaatgaggcc atagaccagc gcagcaaaag caccaaaagt
     9901 gacaaaagcc tgctcttgcg agaatccaag ctgtttaacg aagaaaaccg ccagtacgcc
     9961 ctgcacgccg tagtagccga atcgctccca taactcgaca aaaaagatca tgaaaaatgg
    10021 gcgaggttgc tgcagcatcc ccatgggtgt tgttgtattc atatttatta accttccaat
    10081 accatcctga aaagtatgaa cgcgtaaggg ataacgcgcg aaaaagttta catctgtcag
    10141 agattcttaa tattgatgcg gtgaatagat taatacacta ttacaacaga aaataaccag
    10201 atgatcacac taatgatgga aaatatgatg gtgttaaatg ttgtattggc tggggatttt
    10261 gattgcgtac gcagaccgta ggccagataa ggtgtttacg ctgatcaggt aacaaggcgc
    10321 gccaaaaagc aaaacgcccg catatgcggg cgttcaggaa cacgtcgtag agggaagatt
    10381 attcttcttc gtcgcgcagc ggaacaatca gcatatcaac gtgaacggtg ttgatcagct
    10441 gacgtgcgga agacatcagt ttgctccaga agtcctggtg gtgaccacaa accaccaaat
    10501 ccatatcgta tttcttgatt gcatcgacca gaacctggcc caggtcgccg ctgccgctca
    10561 gggtttcagt gattgggtag cctgcattag tggaaagctc ggtcagtgca tgatgtgtct
    10621 cttcagagat gcgtttctgc atatcaccca gattcacatc aataagcccg gtgtataggt
    10681 cagagtagtt tacatctacg tggatcagag aaactttcgc attgtagggg cgagccatag
    10741 agactgcttt ctctaccaga actttgcttt ccggggagag gtcgaccgcg atgagaatgt
    10801 gtttataagc catagtgtta ctccttccat aaagttgtcg atgactggcc agctagcgtt
    10861 tcttgtgccg ttacgtcacc cgcgtcctgc gaactacgtg cgcggggcta acccagccgt
    10921 aaagattcag tgttaagacc atccttacct tatagcgacc cggatgatcc gtcaatccgc
    10981 cttgcttact cgttagataa acaaattttc gacatgaata tattgatagt ggttaacctt
    11041 ctggaaaaaa aacaacctga tctcctacac tatctataga gccgctcgta tgttggtcac
    11101 cacaaaagcg gtttctccag gacctggtgt taactgattg gcagcgtatc gggagcggta
    11161 gccccggggt ggaactccgc gggcaggtcg ccggggagga ggtatgataa gcaccgtcgc
    11221 attattttgg gctttatgtg tcgtttgcat tgttaacatg gcgcgctatt tctcatcact
    11281 acgcgcgttg ttagtggtac tgcgtaactg cgatccattg ctctatcaat atgttgatgg
    11341 agggggcttt tttacctcac atggccaacc caacaaacag gtgcgtctcg tttggtatat
    11401 ctatgcccaa cgttatcgcg atcatcacga tgatgaattt attcgccgct gtgagcgggt
    11461 gcgtcggcag tttattctga ccagcgcatt gtgtggtctg gtggtggtca gcctgattgc
    11521 attgatgatt tggcattaag cacttcagca ataataacgc ataaaaaaag cgggccagta
    11581 aactgacccg ctcgagactg attacaaacg caaaattgcc tgatgcgcta cgcttatcag
    11641 gcctacataa tctctgcaat ctattgaatt tgcatgtttt tgtaggccgg ataaggcgtt
    11701 cacgccgcat ccggcatgaa caaagcgcac tatgtcacaa tctgaagcgg gccagctgac
    11761 ccgctcgttt tggtgcgtac gattacagga actgcaagga gagccagtac agcccgccgg
    11821 aaagcagtac cgcagccgga agggtaaaca cccaggccat cagaatgctg gtcacggttt
    11881 tacgctgtaa gccgccacca tctaccacca tcgtccccgc gacagaagag gagagtacgt
    11941 gagtagtgga aaccggcatc ccggtataac tcgccaggcc gatagacact gccgccgtca
    12001 tctgggcaga catcccctga gcgtaggtca tgcctttctt accgattttc tcaccgatag
    12061 tcgttgccac acggcgccag ccaatcatcg taccgatacc taacgccagc gcgaccgcca
    12121 tgatgatcca caccggtgca tactcgatgg tgctaagcat gtcggacttc agtttcttca
    12181 acaggcgctg atcgtcagca ctcacgccag gcatcttcac cactttgtcg atagtgtcag
    12241 aaacgcacag cataatgcgg cgcatctggc tacgttgatc aagcgacagc ttgtcgtagc
    12301 tttccacatc ggtggtcaac atacctttca ggcggttgag cgcgttaatg gtattcgacg
    12361 gatggcagtg gaactccgca ggttgcgttg cgccagcttc cggagccggt actaactgat
    12421 cagcaccggt agcctgtttg agcagcgcag gatgctgctc aaagtaagct tcgacgttgt
    12481 tgatggcatc acgggtacgg gtgatttcgt agccagtggc attcatgttc accacgaagc
    12541 ctgctggcgc gacgccaatc aataccaaca taaccagacc aatgcctttc tgaccatcgt
    12601 tcgcgccgtg cgaaaacgcc acgccgatag cggaaaggat cagcgcaata cgcgtccaga
    12661 acggcggctt tttcttgccg tctttctttt cacgctccgc tggggtcagg tggatacggg
    12721 cgcgtttctt ggtgccgctc cagtagcgac gcagcaagaa aatcagaccg ccagcaaaca
    12781 ccaggccgac aataggggaa acgatcagag aaccgaaaat acttaatact ttcgggatat
    12841 tgagtgcatc caccactgac gtcccggtca tcaacgcatt ggttaaacca atcccgatga
    12901 tcgcgccaat cagcgtatga gagctggatg caggtaaacc aaagtaccag gtacccaggt
    12961 tccagataat cgccgccagc aacatagaga acaccatggc aaggccatga gacgatccca
    13021 tattaagcag cagatccgtc ggcagcatat gcacaatggc ataggcaaca ctcagaccac
    13081 ccagcaaaac acccaaaaag ttgaataccg ccgccataac cacggcgagc tgagaacgca
    13141 tcgcgcgggt atagataacg gttgccacgg cgttggctgt gtcatggaaa ccattgatgg
    13201 cttcgtagaa cagcacaaaa gccagtgcaa gcaataataa cagcccggta tgcaaatcca
    13261 ggccagcaaa caaatgtagc ataggacgtt acgccatttt gaggacatga acgcggcgca
    13321 ttatcagtga ctttcgcggc gcgggcaaag tgaaatatag actttttttg atttgccccc
    13381 tgtatggatt tcactcaaaa aataattatc ttatataatt caggcaaata cttcctttta
    13441 gtaatattga tgctggtgcg accactgagg aatctttaca attcacgccc gttttttcta
    13501 agaggagcgc aacgtggaaa ggtttgatgc cattattata ggcgctggtg cggcgggtat
    13561 gttctgttct gcgctggcag gtcaggcagg acgccgggtt ctgctgatcg ataatggtaa
    13621 aaaaccaggg cgcaaaatcc ttatgtctgg cggtgggcgc tgcaacttta ccaaccttta
    13681 tgtcgaacca ggcgcttatc tgagccagaa tccgcatttt tgtaagtctg cactcgcacg
    13741 ttttacccag tgggatttca ttgatctggt caataaacac ggcatcgcct ggcacgagaa
    13801 aacgttaggg caactcttct gcgatgactc cgcgcagcag attgtcgaca tgctggtgga
    13861 tgagtgcgag aagggcaatg tgaccttcag attgcgtagc gaagtgctga gtgtggcgaa
    13921 ggatgaaaca ggcttcacgc ttgatctgaa cggcatgact gtcggttgcg aaaagctggt
    13981 catcgcgact ggtgggctgt caatgccggg gctgggcgcg tcgccgtttg gttataagat
    14041 tgccgaacaa tttggcctca acgtgctgcc gacccgcgcg ggtctggtgc cattcactct
    14101 gcataaaccg ttgctcgaag agttacaggt gctggcgggc gtggcggtgc cttccgtgat
    14161 taccgctgaa aacggcaccg ttttccgtga gaacttactc ttcacccacc gcggcttgtc
    14221 tggaccggcg gtgttgcaga tttcaagcta ctggcaaccg ggggaatttg tcagcatcaa
    14281 tctgctaccg gatgtggacc tcgaaacctt cctgaatgag cagcgtaacg cacatccgaa
    14341 tcaaagcctg aaaaacacac tggcggttca tctaccgaag cggttggttg aacgcttaca
    14401 gcaactcggg caaatcccgg atgtttcgct aaaacagctc aacgtgcgtg accaacaggc
    14461 actgattagc acattgaccg actggcgcgt acaacccaac ggcactgaag gctatcgcac
    14521 tgccgaagtg acgctcggcg gcgtggacac caacgaactc tcttcacgga cgatggaagc
    14581 gcgcaaagtg cctgggctgt acttcatcgg cgaagtgatg gacgtcaccg gctggctggg
    14641 gggctataac ttccagtggg cgtggtcgag tgcgtgggct tgtgcgcagg atttgattgc
    14701 agcaaagtcg tcctgaccta tttcctaaag atgaaaatta ttagagtcgc attaaaaatg
    14761 agctaatttt gatagtggtt atcttgtgat tattttctaa tgagcccgtg aactgaaacc
    14821 ctccatgctt aatataaggt ggatggaaag gtgattgaaa actcacccag tggccagatc
    14881 tttatgaaat atgaacaggt tgaaaaaaac agtaactttg ctgtttttta tacttaacca
    14941 ctatgcatta atgctgcgtt atttcatgat gcctaagaaa aaccagcgtt acgcaaatgg
    15001 tcaacgctgg ttttatccgg tacgttgcaa ttatttttta gcagaacccg cttctaatat
    15061 tgaaacgatt gagaacaacg taaagcatac cgctcccaaa ccgaccagaa ctcgcgaagg
    15121 aataaaatat cccatgtcgg tctgcgccat ttccgcaaga aacgatgcca ggaaaaggca
    15181 aaacaggcag gtgaagacgg gaatcatcgg tattctgttg gctaacgaac aggtacgtct
    15241 ccataccagt gccagtagcc agacttttga gaatatgctg taacagatca ttccgaggca
    15301 aataagaata atgccgggag ccagtcgggc gcttgcatcg gaactgacta agacgtatat
    15361 cccctgcagt accgtgattg agccgagaaa aataacccaa taacaccaca gccagtgttc
    15421 tttagttgaa aacgtattac gtgtttgatg gacaattgtg gcaacaaggc caattagaca
    15481 ggcacagatt gcggttaacc caagcaatac gtgacccgcg acataatgcg gagttatgtc
    15541 agcactacgt aacagcgtaa tagaccaaat gaaaccgagc agggtgagta aaacgggaac
    15601 ggcaatgagg cagttaccga ttaatgaaga ataagcctgt accggtgttc cgtcgctctt
    15661 gctccccgct gcatttttgg gaatgagcag aaagtgaccg gatgacgctg ccaccgtcga
    15721 tacacaggcg gcaatcatac caacgccgaa aataacatgg ccggcgacaa actcgtctgc
    15781 catcacatca ttgcctgcta acagtgccca accccatatc atggtgataa ttgaccccgc
    15841 atagccaata atggggaaca atgtattgta aaacgtatta acgccgcgcg tgagctgcga
    15901 aatgataata aatgcggtag tgaataatgc caggcatatg gccgccagag aaatcagcac
    15961 atgacccgcg acgaaatact cgctttgccc tgaactttcc agcacaaagc cacctaacgc
    16021 gatacaaatt aagcccataa tcaaagggat taatttgaaa agccacccga tatatatgtt
    16081 cactttaaac tcctcaggta tccctgctaa tattgaaata tgcattaatg ataatttcat
    16141 cctgttaata taatgacgag atatcattaa agacaaatgc atagca
//
LOCUS       DAPHKZ010000102        15975 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.102, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000102 DAPHKZ010000000
VERSION     DAPHKZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15975
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.102"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..705
                     /locus_tag="RH288_003398"
                     /pseudo
     CDS             1..705
                     /locus_tag="RH288_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415181.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
     gene            702..2153
                     /gene="djlC"
                     /locus_tag="RH288_003399"
     CDS             702..2153
                     /gene="djlC"
                     /locus_tag="RH288_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlC"
                     /protein_id="HDV4032427.1"
                     /translation="MKTCWQILEIESTTQIDIIRQAYLARLPLCHPETDPQGFKALRQ
                     AYEEALRLAVNPVEEADDEEKDAAAEHEILRAFRTLLDSESDRFQPSAWQKFIQQLNT
                     WNMEDVDQLRWPLCAIAIEARYLSLNCASLLAERLNWHSFNDSEGMDEEEREAFLEAI
                     QAGDCFDFLSLLEYPIALQNQTVEYYFALERCCRYHPDYVTAFLAMEGPWLIPDDAKL
                     HRKLLRWYSSVQTGMAELIPVAQQWQTEEPESEDARYYLCAQRLYCGEGESLLADLCA
                     YWESYPSTQADNLLLQWSKRHCPDYFALLVMVIEARSMVDAQGQPLKYVPGESARTRL
                     LWAEILHSGKLSPLGQSFIESLFFKRKAWAWWKSRVGSETEQDSPFLDLYRVAEQVVL
                     EAFPKQEMLARLNTRLEGGDAHPLEAIVTRMLLTKVKLEPEDEDVDEPTPENHEEKND
                     EGEKPQSITSIIKISLTVLVIGYALGKIAMLFS"
     gene            complement(2213..3883)
                     /gene="hscC"
                     /locus_tag="RH288_003400"
     CDS             complement(2213..3883)
                     /gene="hscC"
                     /locus_tag="RH288_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscC"
                     /protein_id="HDV4032428.1"
                     /translation="MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIIS
                     MDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSL
                     KEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
                     HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRA
                     DVARTTLNESELAALYACVEAAKCSNQSPLHIRWQYQEETRECEFYENELEDLWLPLL
                     NRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIV
                     ALGAAIQAACRLRSEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRV
                     ETYSTMHPEQDSITVNVYQGENHKVKNNILVESFDVPLKKTGAYQSIDIRFSYDINGL
                     LEVDVLLEDGSVKSRVINHSPVPLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEE
                     LWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASDYLAIEIP"
     gene            complement(3967..4902)
                     /gene="rihA"
                     /locus_tag="RH288_003401"
     CDS             complement(3967..4902)
                     /gene="rihA"
                     /locus_tag="RH288_003401"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HDV4032429.1"
                     /translation="MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEK
                     TLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNC
                     TAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAE
                     LLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTSVERWVGVETQGKYTQGMTVV
                     DYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA"
     gene            complement(5020..5745)
                     /gene="gltL"
                     /locus_tag="RH288_003402"
     CDS             complement(5020..5745)
                     /gene="gltL"
                     /locus_tag="RH288_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HDV4032430.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRDKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDS
                     PKDAFFDDPKSDRAKDFLAKILH"
     gene            complement(5745..6419)
                     /gene="gltK"
                     /locus_tag="RH288_003403"
     CDS             complement(5745..6419)
                     /gene="gltK"
                     /locus_tag="RH288_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HDV4032431.1"
                     /translation="MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVM
                     RLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSY
                     LKRRTA"
     gene            complement(6419..7159)
                     /gene="gltJ"
                     /locus_tag="RH288_003404"
     CDS             complement(6419..7159)
                     /gene="gltJ"
                     /locus_tag="RH288_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HDV4032432.1"
                     /translation="MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAF
                     LVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVIPELLPEKIGMWFKA
                     ELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAFIMLVMTLVERKVRLPGNMGGK"
     gene            complement(7329..8237)
                     /gene="gltI"
                     /locus_tag="RH288_003405"
     CDS             complement(7329..8237)
                     /gene="gltI"
                     /locus_tag="RH288_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter
                     substrate-binding protein GltI"
                     /protein_id="HDV4032433.1"
                     /translation="MQLRKPATAILALALSAGLAQADDAAPAAGSTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFANLKDKAVVVTS
                     GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKEPNDKALN"
     gene            complement(8634..10172)
                     /gene="lnt"
                     /locus_tag="RH288_003406"
     CDS             complement(8634..10172)
                     /gene="lnt"
                     /locus_tag="RH288_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HDV4032434.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGL
                     QALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLS
                     LYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
                     KGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQP
                     EKTIQVSMVQGDIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEIN
                     QQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSANGIELTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTALFGFAAVLMSLR
                     QRRK"
     gene            complement(10197..11075)
                     /gene="corC"
                     /locus_tag="RH288_003407"
     CDS             complement(10197..11075)
                     /gene="corC"
                     /locus_tag="RH288_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308723.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HDV4032435.1"
                     /translation="MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA
                     SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVKIPDDSPQPKLDE"
     gene            complement(11165..11632)
                     /gene="ybeY"
                     /locus_tag="RH288_003408"
     CDS             complement(11165..11632)
                     /gene="ybeY"
                     /locus_tag="RH288_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014169133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDV4032436.1"
                     /translation="MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIR
                     VVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGK
                     PLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE"
     gene            complement(11629..12669)
                     /locus_tag="RH288_003409"
     CDS             complement(11629..12669)
                     /locus_tag="RH288_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415193.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDV4032437.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDIEPEQIHLAIKEARVLEQSAESV
                     PEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREEQEQK"
     gene            complement(12822..14246)
                     /gene="miaB"
                     /locus_tag="RH288_003410"
     CDS             complement(12822..14246)
                     /gene="miaB"
                     /locus_tag="RH288_003410"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDV4032438.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSY
                     SFIFSVRPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENDLGVGYYQP"
     gene            14392..15567
                     /gene="ubiF"
                     /locus_tag="RH288_003411"
     CDS             14392..15567
                     /gene="ubiF"
                     /locus_tag="RH288_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HDV4032439.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQHGFAVTVIEHAEPAPFVA
                     DSQPDVRISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVVFDAAELKL
                     PLLGYMVENTVLQQALWQALEAHPKVTLRVPGSLIALHRHDDLQELELKGGEVIRAKL
                     VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPL
                     FDNWASLVWYDSPARIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGAFPLTRRHAL
                     QYVQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRY
                     QMRRMADNFIMQSGMDLFYAGFSNNLPPLRFMRNLGLMAAERAGVLKRQALKYALGL"
     gene            complement(15721..15795)
                     /locus_tag="RH288_003412"
     tRNA            complement(15721..15795)
                     /locus_tag="RH288_003412"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15761..15763),aa:Gln,seq:ctg)
     gene            complement(15843..15919)
                     /locus_tag="RH288_003413"
     tRNA            complement(15843..15919)
                     /locus_tag="RH288_003413"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15883..15885),aa:Met,seq:cat)
BASE COUNT         3859 a         4087 c         4143 g         3886 t
ORIGIN      
        1 aataaggaag aacaatatct tctttttgcg ctttctgcgc ccatggaaat acttaatcag
       61 ggttgcaaac ccgcgcatga ctcgccaaaa atgtatactg ggataaaaga attcgagctc
      121 tcatcatcct ggggaataaa taatcgtgat gatttaattc agactattta tcagatgact
      181 gatgatggtc atgccaatga tttagctggc ttatatctga catggcatcg ctcttcccct
      241 gaagagtgga aagcattaat tgctggtggc tcggagagag ggttgattta tacccaattc
      301 gttgcccaaa ccgctatgtg ctgtggggaa gggggaatca aagcctggga ttatgttcga
      361 atggggtttc tgtcacgggt cggtgtgctc aacaagtggc tgacggaaga agagagttta
      421 tggctgcaat cgcgcgtcta tgtacgagct caccattact atcacagctg gatgcactat
      481 ttttccgcct attcgttagg acgtctctac tggcaatctt ctcagtgcga agacaacact
      541 tcgctacgcg aggcgctaac cctgtacaaa tacgatagcg ccgggagtcg tatgttctaa
      601 gagctggcag cgggaagcga tcgtttctat gccacgcttc cctggcagcc attaactgtc
      661 cagtctgaat gcccggtaac gcttaaggat gtgagcgacc tatgaaaaca tgttggcaaa
      721 tcctcgaaat tgaaagcacg acgcaaatag acattatccg ccaggcttat cttgctcgct
      781 taccgttgtg tcatcccgaa accgatccgc aagggtttaa agcattacgc caggcctatg
      841 aagaggccct gcgactggcg gtaaatcctg tcgaggaagc agatgatgaa gaaaaagatg
      901 ctgccgctga acatgaaata ctacgtgcat tcaggacatt actggattca gaaagtgatc
      961 gttttcagcc ttccgcctgg cagaaattta ttcagcaatt aaatacctgg aacatggagg
     1021 atgtcgatca attacgctgg ccgctgtgtg caatcgccat agaagcgcga tatctttcat
     1081 taaattgtgc ttctttgctg gcagagcgtt tgaactggca ttcatttaat gacagcgaag
     1141 gaatggatga ggaagaaagg gaggcttttc ttgaggccat tcaggctggt gattgtttcg
     1201 atttccttag ccttctggaa tatcccattg cgttgcagaa ccagactgtt gagtattact
     1261 tcgcgctgga acgttgctgc cgttaccatc ctgactatgt cactgcgttt ttggcgatgg
     1321 aaggtccgtg gttaattcct gatgatgcaa agttacatcg caaactgttg cgctggtaca
     1381 gctcggtgca aacaggtatg gcggaactca ttcctgtcgc tcaacagtgg caaacggaag
     1441 aaccagaaag cgaagatgcc cggtattact tgtgtgcaca acgtttgtac tgcggcgagg
     1501 gggaaagcct gcttgccgat ctctgcgcgt actgggaaag ttacccatct acacaagctg
     1561 ataatttgtt gttgcagtgg agcaagcgtc attgcccgga ttatttcgcg ttattagtga
     1621 tggttatcga agcgcggagc atggtagatg cgcaaggtca accgctgaaa tatgttcctg
     1681 gtgagagcgc ccggacgcgg ctgttatggg cggagatttt acatagcgga aaattatcgc
     1741 cgttaggtca atcgtttatt gagtcgttat tcttcaagcg caaagcatgg gcgtggtgga
     1801 aatcgagagt cggtagcgag acagagcaag attcaccgtt cctggatttg tatcgggtag
     1861 cggaacaggt agtacttgaa gcgtttccga aacaagagat gctggcccgt cttaatacaa
     1921 ggctggaagg cggagatgct catccattag aggccattgt cacccggatg cttttgacga
     1981 aagtgaaact cgagccggag gatgaagatg tcgatgagcc aacacctgaa aatcatgaag
     2041 aaaaaaatga tgagggtgaa aaaccacaga gcattaccag cattatcaaa atcagtttaa
     2101 cggtgctggt gataggttat gctctcggca aaatcgcgat gttgtttagc tgacgatgtg
     2161 ttttttgcgc cgatgccgga tgcagcgttt acgccgcatc cggcagccgt gtttatggga
     2221 tctcaatggc taaataatcg ctcgcccgcc gccgaacttc atccacgcgg gccatatcgt
     2281 ttgactgcaa cgccgcatca aaatcggtga tcacccggcc gatctcttct cgctcgtcac
     2341 ccagcgcccg cgcccacaac tcttccagtt tggctttaaa ggtgcgattg atgagcatat
     2401 cgcgcggata aattttcaat gcggataacc gcgtccgact ctcttcaatc tgctgcgcgc
     2461 tcaatggtac cgggctgtgg ttaatcactc tggacttaac gctgccgtct tccagaagca
     2521 cgtcaacttc aagcaacccg ttgatatcat aactaaagcg aatatcaatc gactgataag
     2581 ccccggtttt cttcaacggc acatcgaagg attccaccag aatgttgttt ttaactttgt
     2641 ggttttctcc ctgatagacg ttaaccgtaa ttgaatcctg ttccgggtgc atggttgaat
     2701 aagtttctac acgcgacacg ggcacagtgg tgtttcgttc aataatcggc gagaaaatgc
     2761 cggaaacgcc ctggcggtta acttcaacgc ccaacgagta agggcaaata tcagtgagga
     2821 ttacctcttc aatatcttca ctgcgtaagc ggcaggcggc ctggattgct gcgcccagcg
     2881 cgacaatggt gctcggatcg taactttgat acggtaattt gccaaacaga cgcacggcga
     2941 ttcgctgcac cagcggcatt tgtgacgcgc cgccaaccag caccagactg tcgatttgac
     3001 tcggcttcag acgcgcatcg cgcaacgcct gttcaatcgg cactcgcaag cgattgagca
     3061 gcggcaacca caaatcttcc agttcgttct cgtaaaattc gcattcccgc gtttcttcct
     3121 gatactgcca gcgaatgtgc aatggcgatt gattgctaca ttttgccgct tccacacagg
     3181 cgtacaaggc tgccagttca ctctcgttaa gcgtggtcct ggcgacatcc gcgcgtttta
     3241 aaacctcatc gaccagcata tgggtaaaat cttcgccacc aagaaagttg tcgccagcgg
     3301 aggcgtgaac ttcaatcacc ggcgtggcgt actcaagcac cgtaacgtca aacgtgccgc
     3361 caccgagatc aaacaccagc gaacgggtat tttgttgggt atgcaggcca tacgccatcg
     3421 cagctgctgt gggttcatta attaagcgta ccgcatttaa cccggctaac tccgctgcta
     3481 aacgggtatg cttgcgttgt tcatcgctga aataagccgg aacggagatc accacatctt
     3541 taatcggacg ttgcagaaat tcttcggcat cttcttttaa tgagcgtaat accaaagagg
     3601 acagttctgg cgcgttaaat gtgtcgctgc ctaaccgcca gttggtatta ctgcccattg
     3661 cacgtttaaa taacgctgcc gttttatccg gatgcgaagt acgccgtgat acagccggtt
     3721 ttccgactaa aatatgatta ttttcatcca tgctaattat ggatggtgtt aaatattcac
     3781 cgaacttatt tggaattaat tgcgcggcac cgtctttcca gacggcaatt aaactattgg
     3841 tagtaccgag atcgatacca atggcgagtt ctgcattatc cattgcattt atatcttgaa
     3901 agaaaaagag ataaacagat taagaccacc caggtaacgc gtggtgatct taatcaatga
     3961 cgtgtgttaa gcgtaaaatt tcagacgatc agccagtaaa tcaacaaagc cctgacgatc
     4021 aacatcgacc attacggtgg cattcggttt attgcctgtc agataataat aatcaacaac
     4081 cgtcataccc tgggtatatt tcccctgtgt ttccacgcca acccagcgct caacagaggt
     4141 aaataactcc ggtttcaaca gccaggcgat ggtgcatggg tcatgcagtg gtgcgccgac
     4201 aaagccccat ttttcgtctt tatgatattc gaggaagaaa tccagcagtt cggcaacaat
     4261 ggttgaaaca gggttaccaa tcgcgcggaa acgctcggtg tcttcaacgt ggatttgtgc
     4321 tttatgagta acatccagac cggccatcac caccgggatc cctgactgga agacaatttc
     4381 tgccgcttcc gggtcaacgt aaatattaaa ttcagccgca ggcgtccagt tacccagccc
     4441 catagcgcca cccataatca cgatacgggc aattttgcta tgcagttccg gatggctatt
     4501 gagcagcaag gcaacgttag tttgcggtcc ggtagacaca atggtgacag gttccgcact
     4561 ttcacgcagc gttttcgcca tcagctctac cgccgtacag ttttgcggtg cgaatgtcgg
     4621 ttccggtaat gccgggccgt cgagaccgct ttcgccgtgc acattgtccg cgataatcaa
     4681 ctcacgcatt aacggtttta ccgcgccgcc tgctaccgga atatcggtgc gattaagcaa
     4741 ggtcagcata cgcagaacat tgcgtaaggt tttttctggt gtctggtttc cggcggaaga
     4801 cgtaattgct ttgacatcaa gctctggtga ggcgagggcg agaactattg cgatagcgtc
     4861 gtcatgacct gggtcgcaat ctaacagaat tggcagtgcc attgttgctc cttgttgtgt
     4921 gcttctttgc gacaagggta acgccaggat gtaacagata cgaggggcga aacgataaag
     4981 cgtgagatgg cgcgcaattg ggtatgcgcg ccagagtgat taatgcagga ttttcgcgag
     5041 gaagtctttt gcgcggtccg atttcggatc atcgaagaaa gcgtctttcg gcgagtcttc
     5101 gacaatttta ccctcgtcca taaagatcac ccgattcgcc actttacggg caaagcccat
     5161 ttcgtgggtc accaccatca tggtcattcc ttcgttcgcc agttccacca tcacgtccag
     5221 tacttcgttg atcatctccg gatccagcgc cgatgtcggt tcgtcaaaca gcatcgcaat
     5281 aggatccata cacaacgcgc gagcgattgc cacacgctgc tgctgaccgc cggaaagctg
     5341 cgccggaaac ttattggcgt gagcagaaag cccgacacgc tccagcagtt tcagggcttt
     5401 ttcacgagcc ggcgctttat cgcgtttaag cactttcacc tgcgccaggg tcaggttttc
     5461 gataatcgac agatgaggga acagctcgaa atgctggaat accatcccga cgcgggaacg
     5521 cagctttgcc agatcggttt tcttgtcgtt aaccacgata ccatcgacgg tgatttcacc
     5581 ttgctgcacc ggttcgaggc cgttgacggt tttaatcagc gttgatttgc cggaaccaga
     5641 cgggccgcaa accaccacca cttcgccttt tttcacttcg gttgagcagt cggtcagcac
     5701 ctgaaagtga ccataccatt ttgaaacatt tttcagggta atcattatgc tgtccttctt
     5761 ttcaagtagc tgaccaacaa cgacgcgcta agactaataa cgaaataaac aaatccggca
     5821 aacaggatca tctcaacctg cgtaccatca cgctcaccaa tggttgaggc ggtacggaag
     5881 aaatcggcca gggataacac atacaccagt gaggtatcct ggaacagtac gatgccctga
     5941 gtgagcagca gcggcaccat cgcgcggaac gcctgcggca gaataatcag tttcatcgac
     6001 tgccagtgag tcattcccaa cgccagcgcg gcgctcgatt gaccacgaga aatactttga
     6061 ataccagcac ggataatctc tgaatagtag gccgcttcaa acatcgaaaa cgccaccatc
     6121 gccgaaatta aacggatatc attttttggc gataatccca gcacgttttg cagaaaaccc
     6181 ggcacgatca ggtaaaacca cagcaaaacc ataactaaag gaatcgagcg gaatacgtta
     6241 acgtaggctt tggcaaacca cgccacgggc gcaaagctgg ataaacgcat caccgccagc
     6301 atcgtgcccc acaaaatacc aatcactacc gccgtgacgg tgattttcag ggtgatcacc
     6361 agcccgtcga gcagatatgg cagggaaggg acaatggaac tccagtcaaa ctcgtacatt
     6421 atttgccccc catgttgcca ggcaggcgaa ctttacgttc aaccagcgtc atcaccagca
     6481 tgataaaagc gttaatcaac acatacgcca gcgtaatggc ggtaaacgac tcccaggcat
     6541 gggctgagta atcgagcaat ttacccgcct gcgccgccat atccaccaga ccgatagtcg
     6601 aggcgatggc ggagtttttc accaggttca tcatctctga ggtcatcggc gggacgataa
     6661 cgcgataagc attaggcagc agtacgtatc gataagcctg cggtagcgtc aggcccatcg
     6721 ccagcgcggc atttttttgc cctcgcggca gcgactgaat cgcggcgcgt acctgttcgc
     6781 aaacacgggc ggcggtaaac agccccaggc agagcatgga tgaaaggaaa aactgaatat
     6841 tgggatccag ctcggcctta aaccacatgc cgattttctc cggcagcagc tccgggatca
     6901 ccagatacca ggtaaagaat tgcacaatca acggcacgtt gcggaacagt tcgacataca
     6961 acgtacccag accagagaga aaacggtttg gaacggtacg taaaatgccg aaaaatgaac
     7021 cgacgaggaa agcgataatc caggcgcaga tcgacaaagc gatcgtcacc tgaaaaccac
     7081 tccagatcca accaagatag gtggtgttgc cgaacggggc ttgttgtaaa aaaatacccc
     7141 agttccagtc tatagacata aatctactcc agaaaaaaga gggtagcagc gttaactgct
     7201 accctcgaag attgttaccc agcgtattgc ggttttcagg cccgatgggg aacgaccatc
     7261 aggcgtatag tctgtccgtg ctacgtaaca atcgagaggg ctggaatttc cgcccctggt
     7321 tcttgtaatt agttcagtgc cttgtcattc ggttctttga acagtgcttt catttcgtct
     7381 gacagttcga aattcatgtt caggtttttc ggcggaattg gatttttgaa ccacttatca
     7441 aaccattttt ccgcttcacc ggaggtctgc acctgagcga tggtgtcatc catcagcttt
     7501 ttgaactgcg gatcatcttt acgcaacata caaccgtagg cctcctgaga ctgcggcttg
     7561 ccgacgattt cccagttgtc tggtttcttc gctttcgcac gttcaccggc cagcagagcg
     7621 tcatccatca taaaggcaac ggcacgaccg ctttccaggg tgcggaaaga gtcaccgtga
     7681 tctttggcgc tgatgatgcg catattcatt ttttgctctt cattcagttt gttgagcaaa
     7741 acttcagagg tagtgccgga agtgacgact acggctttgt ctttcaggtt ggcaaaatct
     7801 ttgatatcgc cacccttttt ggtcaacagg cgcgtaccga ccacgaaaat agtgtcagag
     7861 aaagccgcct gtttttggcg ttcgacgttg ttggtggtag aaccacattc aaaatcgaaa
     7921 gtgccgtttt gcagcagtgg aatacggttt tgtgaggtaa tcggaatcag ttttacctgc
     7981 aagtccggtt tgttgagttt ctttttcact gcttcaacaa tggcgttgga gtaatcctgc
     8041 gagtaaccca ccactttttg ctgattgtcg taataagaga aaggcactga agattcacgg
     8101 tgaccgacga caatcacacc gtttttggcg attttgtcca gagtactgcc cgctgccggg
     8161 gcggcgtcat ctgcctgtgc cagtcctgcg gaaagcgcca gggcgaggat tgctgtggca
     8221 ggtttacgta attgcatatc caactccttt atcttctgcg ttaagaacgc atggataccc
     8281 gttgtgagtg tttgtgttgt tatcgtctgc aactttattg tgcagtgttg tgcctgttag
     8341 gtaacattta gtttggctaa atgtaaagat attgctgttt tattgtttgt ttttgcgaga
     8401 tgcgccgcac cattccgaag caaaattctt aaaatgcact cttttagtgc taccgctgga
     8461 ttactgtggt gcaactaggt tgtactgatg ctgattcagg gtttgccttg tataacaaag
     8521 caatagatgt gccaaagttg gataggagaa tattgttatc cggataatgc actgatgccg
     8581 catccggtga gcgtgccgaa atatgggatg tattccggca cgataagaag ggattattta
     8641 cgtcgctgac gcagactcat caacacagca gcaaaaccaa acaatgccgt cagcacccac
     8701 agcggccagt tgccggtacg tgcgtatggt gtgagtccgg tggtcggcgt cacgttagtg
     8761 gttaacacct cgcgggtgaa ctgcgggatc atcgcctgaa tctcaccctg cgggccaatc
     8821 accgccgtaa tgccgttgtt ggtgctgcgc aacagtgggc gcgccagctc cagcgcacgc
     8881 attcgcgcca tctggaagtg ttgccatgga ccaatagatt taccaaacca cgcatcgttg
     8941 gagatagtca gcagatagtc ggtatccggg cggaagttat cgcgcacttg ctcgccgaga
     9001 atgatctcgt agcaaatagc cgcagtaagc tcaataccat ttgccgacag cggcggctgg
     9061 atatatggcc cacggctgaa cgacgacatc ggcagatcaa agaacggtgc taacggacgc
     9121 agaatcgact ccagcgggac aaactcgcca aacggcacca gatggttttt gttatagcga
     9181 tcggctgatt cgtagctgta cggcgcacct ttacccagcg tgatgatggt gttgtaggta
     9241 tcgtagcggt tctgcttatt gagacgcgcg tcgacaatcc cggttaccag cgagctacct
     9301 ttatcacgca actcaccgtc cagtgctttg aggaacggtt gctgattaat ttccagatcg
     9361 gttatcgccg actccggcca gataatcaac gatgatttgc ccatcagcgg tgccgttgcg
     9421 ttgtagtaaa tcttcagcgt attaagaagc tggccttcgt cccatttcag cgattgcgga
     9481 atatcgccct gaaccatcga aacctgaatg gttttctccg gttgtggggt aaaccactgg
     9541 atgtaacgca gcgggaaggg aagggcaaac agcacgacgg ccaccaccag cggacgccag
     9601 ttgcgtttga ccaacgccag tgccagcagg ccactaacca tcatcagcag gaagttaatg
     9661 gcttccacgc ccattatcgg tgccagccct tttaacgggc catcaatctg gctatagccg
     9721 aactgtaacc acgggaagcc ggtcagtacc caaccgcgca gaaactcggt cacttgccag
     9781 agggcagggg cggcaatcgc tacgcgcagc caggtagttt tcggccacag acgcgacagc
     9841 acgccagcaa acagtccggt atacagcgac aaatacgccg ccagcagcac caccaggaag
     9901 atgttaaccg ggccaggcat tccgccaaag gtcgcgatgc tgacatagac ccagttaata
     9961 ccgctgccaa agaggccaaa tccccagcaa aagccaatag cggcagactg gagtggacgg
    10021 cggttaaagg tcaacgcctg aagccccatc agcgaaataa tcgccgcagg ccagacgtcg
    10081 taaggagaga aggccagcgt tccgcaggca ccgaataata acgccagcag caggcgaatg
    10141 cgctggcgtt caattaatga ggcaaaagcc atgtagttat ctatccagtt tcggttttat
    10201 tcatccagct tcggctgggg tgagtcatcc gggattttga catgaacctg aataatacgc
    10261 cgactgtcgg ccatcgccac tttgaactgg taaccgtcga tgtcgatagt ttcgccacgc
    10321 gccggaagat gcccaaatgc ctgcatcacc agaccaccga tagtgtcgac ttcttcatcg
    10381 ctaaagtggg tgccgaacgc ttcgttgaag tcttcaatgg aagccagtgc gcgtacggtc
    10441 caggtatgac gactcagctg acggaagtcg atatcatctt cttcgtcata ctcgtcttca
    10501 atctcaccaa caatcagttc caggatgtct tcaatggtca ccagaccgga aaccccaccg
    10561 aattcgtcaa taacgatcgc catgtggtaa cgctgagagc gaaactcttt cagcatccgg
    10621 tctacgcgct tactttcagg aacgacaacc gcctgacgta acactttgtc catgctgaag
    10681 gcttcagcat cgctgcgcat aaacggcagc aagtctttcg ccatcagaat cccttcaatg
    10741 tgatctttgt cttcgctaat caccgggaaa cgtgagtggg cggactcgat gatgacatca
    10801 agacattcgt ccagcgtctg gttgcgtttc agggtaatca tctgggagcg ggggatcatg
    10861 atgtcgcgaa cgcgttggtc tgcgatgtcc atcacccctt cgagcatatc gcgcgtatct
    10921 tcgtcgataa ggtcgttctg cccggaatca cggatcagcg ccagcagttc gtcacggttt
    10981 ttcggttcac cgtggaaaag ttggctgagt aacagggaga aaaatccctt cttgttgctt
    11041 atcgtgtcac tactgtgtga attgtcgtcg ctcatggcgt cgtatgggtt ctcatgttag
    11101 ttaatcaaaa cgccgtcgtt aatcaccaac ggcggggacg tctgccagtc aaatgcctgg
    11161 caaattattc tttctcggca atgtacggat cctcatagcc cagagcaagc ataatctctg
    11221 tttcgagggc ttccatttct tctgcttcgt catcttcgat gtgatcgtaa cctaacaaat
    11281 gcagactgcc gtgcaccacc atatgcgccc agtgcgcctc cagtggtttg ccttgctcct
    11341 gagcttcctt ctcaaccacc tgacggcaga taaccagatc gcccagtagc gacatttcca
    11401 tgccaggcgg cacttcaaac gggaaggaga gcacgttggt cggcttatcc ttaccgcgat
    11461 aggtcagatt cagactgtgg ctttcggcgg tatcgaccac gcgaatcgtc acttccgatt
    11521 cttcctgaaa ctgcgggatc accgcattca gccatgtctg aaactggctc tcttccggta
    11581 acccggaatt atcttcacat gccagttgta aatcgaggat cacctgactc atttttgttc
    11641 ctgttcttcg cgcttgcgtt ctgctgccag cgccgctttt cgtttttgtt cggcttcttc
    11701 ccaggcttca taggcgttaa cgatacgcgc caccacaggg tgacgaacca cgtcttcgct
    11761 gtggaagaag ttaaagctga tctcttcgac atcggccagc acttcgatgg cgtgacgtaa
    11821 gcctgattta gtattacgcg gcaggtcgat ctgtgtgacg tcgccggtga taaccgcttt
    11881 tgagttaaaa ccgatacggg tcaggaacat cttcatctgt tcgatggtgg tgttctggct
    11941 ctcatcgaga atgataaacg cgtcgttcag cgtacgacca cgcatatagg ccagcggtgc
    12001 gacttcaata acgttgcgct caatcagttt ctcgactttc tcaaagccca gcatttcaaa
    12061 cagcgcgtcg tacagcgggc gcagatacgg gtctactttc tggcttaaat cgccaggcag
    12121 gaagcccagt ttctcaccgg cttctactgc cggacgagtc agcagaatac ggcgaatttc
    12181 ctgacgctcc agggcatcaa ctgccgcagc cactgccagg taggttttac ccgtacccgc
    12241 cgggccaacg ccgaaggtaa tgtcatggtc gagaatattg gcgatgtact gcgcctggtt
    12301 tggcgtgcgc ggcttaatta cgccgcgttt ggttttgata ttgaccgctt tgccgtactc
    12361 cggcacgctc tccgcgcttt gctccagtac ccgcgcttct ttaatcgcaa ggtggatctg
    12421 ttccggttcg atatcctgaa tctgaccgcg catcggggca gtatcgacat acaggctacg
    12481 cagaatgtct gccgcagcgg tgacgcaaat cggacggccg gtcagtttaa agtggttatc
    12541 gcggcgattg atctcgatgc cgagacggcg ttcgagctgc ttgatgttgt catcaaacgg
    12601 gccgcacagg ctcaacagac gcgcattgtc tgctggctcc agggtgattt cgcgagtgtc
    12661 tatgttcaaa ccgttcctct tatctgtatg ccgccggaag ctgaacattc accggcctat
    12721 aaggaaatta ttcacgccac aggaaaaagg cgcaagcatt gcaataaaga tggggataaa
    12781 gagagaaaaa acaaggccca ccggaacggc aggcctgaga attacggctg ataataaccc
    12841 acgccaaggt cgttttcttt gcgggtacgg gcaatcactg attccggtgt ttctgccacg
    12901 cgcagaccca tttcatcttc agtacgcacc actttaccgc gcagagagtt cgggtagacg
    12961 tcggtaattt ctacatcgac gaatttaccg atcatatccg gcgtgccttc gaagttgacc
    13021 acgcggttat tttccgtacg cccggaaagc tccatgatgc tcttacgcga tgtaccttct
    13081 accagaatac gctgggtggt gccgagcatc cggcggctcc acgccatcgc ttgctgatta
    13141 atgcgctctt gcagaatata cagacgctgc ttcttctctt cttccggaac atcatcaacc
    13201 atatcggcgg ctggtgtacc cggacgtaca gagaagataa agctgtagct catgtcgaaa
    13261 ttgacgtcgg caatcagctt catcgttttc tcgaagtctt cggtggtttc gccagggaag
    13321 ccaacgatga aatcagaact gatctgaata tctggacgcg ccgcacgcag tttacggatg
    13381 atcgctttgt actccagcgc cgtatgggta cggcccatca ggttcagaat gcgatcggaa
    13441 ccgctctgta ccggcagatg caggaagctc accagctccg gcgtgtcgcg atacacttcg
    13501 atgatatcgt cggtgaattc gatcggatgg ctggtggtaa agcgaatacg atcgatcccg
    13561 tcgatcgcag caaccagacg cagcagatcg gcaaacgatc cggtggtgcc gtcgtagttt
    13621 tcaccacgcc aggcgttcac gttctgaccg agcaggttga cttcacgcac gccctgagcc
    13681 gcaagctggg caatctcaaa cagaatatcg tcggacggac ggcttacctc ttcaccacgg
    13741 gtgtaaggca ccacgcagta ggtgcaatat ttattgcagc cttccatgat ggagacaaac
    13801 gcggtcggcc cttcggcgcg cggttccggt agacggtcaa acttctcgat ttccgggaag
    13861 ctgatatcta caaccgggct gcggtcgcca cgcacggagt tgatcatctc cggcagacgg
    13921 tgcagcgttt gcggcccaaa aataatatcg acatagtggg cgcgctggcg aatgtgctcg
    13981 ccttcttgcg atgccacgca gccaccgacg ccgataatca ggtctggatt cttctctttt
    14041 aacagtttcc agcgacccaa ctgatggaag actttttcct gagccttctc gcggattgag
    14101 caggtgttca gcagcagcac atccgcttct tccgccacgt cggtcagttg atagccgtgg
    14161 gtggcatcca gcagatcggc catcttcgat gaatcgtact cgttcatctg acagccccag
    14221 gttttaatat ggagtttttt ggtcatcgac ttgctcttgc gaaatagtag ccaggaatgc
    14281 agggcgcata gtgtaatgct ttgctgccgt tgtgaccagt atgagcgtta tcagccctta
    14341 ggggtaaaaa tcctgtaaac ttaaagcata ttgctaacag gatgattgac catgacaaat
    14401 caaccaacgg aaattgccat tgtcggcgga ggaatggtcg gcggcgcact ggcgctgggg
    14461 ctggcacagc acggatttgc ggtaacggtg atcgagcacg cagaaccagc gccgtttgtc
    14521 gctgatagcc aaccggacgt gcggatctcg gcgatcagcg cggcttcggt atcattgctt
    14581 aaagggttag gggtctggga tgcagtacag gctatgcgtt gccatcctta ccgcagactg
    14641 gaaacgtggg agtgggaaac ggcgcatgtg gtgtttgacg ccgctgaact taagctaccg
    14701 ctgcttggct atatggtgga aaacactgtc ctgcaacagg cgttgtggca ggcgctggaa
    14761 gcgcatccga aagtaacgtt acgtgtgcca ggctcgctga ttgcgctgca tcgccatgat
    14821 gatcttcagg agctggagct gaaaggcggt gaagtgattc gcgcgaagct ggtgattggt
    14881 gccgacggcg caaattcgca ggtgcggcag atggcgggaa ttggcgttca tgcatggcag
    14941 tatgcgcagt cgtgcatgtt gattagcgtc cagtgcgaga acgatcccgg cgacagcacc
    15001 tggcagcaat ttactccgga cggaccgcgt gcgtttctgc cgttgtttga taactgggca
    15061 tcgctggtgt ggtatgactc tccggcgcgt attcgccagt tgcagaatat gaatatggca
    15121 cagctccagg cggaaatcgc gaagcatttc ccgtcgcgtc tgggttacgt tacaccgctt
    15181 gccgctggtg cgtttccgct gacgcgtcgc catgcgttgc agtacgtgca gccagggctt
    15241 gcgctggtgg gcgatgccgc gcataccatc catccgctgg cggggcaggg agtgaatctt
    15301 ggttatcgtg atgtcgatgc cctgattgat gttctggtca acgcccgcag ctacggcgaa
    15361 gcgtgggcca gttatcctgt cctcaagcgt taccagatgc ggcgcatggc ggataacttc
    15421 attatgcaaa gcggtatgga tctgttttat gccggattca gcaataatct gccaccactg
    15481 cgttttatgc gtaatctcgg gttaatggcg gcggagcgtg ctggcgtgtt gaaacgtcag
    15541 gcgctgaaat atgcgttagg gttgtagcct tacaacattg ccggatgcgt gccaaccgta
    15601 ggtcggataa gacgcggcag cgtcgcatcc gacattgaag gataagacgt gtcaacatcg
    15661 cattcgacat tgaatgaacg cagaaaagca aaaagctcgc cgaagcgagc ttttttaatg
    15721 tggctggggt acgaggattc gaacctcgga atgccggaat cagaatccgg tgccttaccg
    15781 cttggcgata ccccaacaaa ttggttttga atttgccgaa catattcgac acattcagaa
    15841 tttggtggct acgacgggat tcgaacctgt gaccccatca ttatgagtga tgtgctctaa
    15901 ccaactgagc tacgtagcca gattgtttct tcgatggctg gggtacctgg attcgaacca
    15961 gggaatgccg gtatc
//
LOCUS       DAPHKZ010000103        15786 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.103, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000103 DAPHKZ010000000
VERSION     DAPHKZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15786
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.103"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            277..681
                     /gene="sdhC"
                     /locus_tag="RH288_003414"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             277..681
                     /gene="sdhC"
                     /locus_tag="RH288_003414"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HDV4032440.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFV
                     AVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFG
                     YLEETFEAGKRSAKISFVITVVLSLLAGVLVW"
     gene            675..1022
                     /gene="sdhD"
                     /locus_tag="RH288_003415"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             675..1022
                     /gene="sdhD"
                     /locus_tag="RH288_003415"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HDV4032441.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     YEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            1022..2788
                     /gene="sdhA"
                     /locus_tag="RH288_003416"
     CDS             1022..2788
                     /gene="sdhA"
                     /locus_tag="RH288_003416"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HDV4032442.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            2804..3520
                     /gene="sdhB"
                     /locus_tag="RH288_003417"
     CDS             2804..3520
                     /gene="sdhB"
                     /locus_tag="RH288_003417"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HDV4032443.1"
                     /translation="MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRNA"
     gene            3721..6522
                     /gene="sucA"
                     /locus_tag="RH288_003418"
     CDS             3721..6522
                     /gene="sucA"
                     /locus_tag="RH288_003418"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HDV4032444.1"
                     /translation="MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRST
                     FQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNL
                     YRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPE
                     AVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT
                     FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAM
                     QEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVE"
     gene            6537..7754
                     /gene="odhB"
                     /locus_tag="RH288_003419"
     CDS             6537..7754
                     /gene="odhB"
                     /locus_tag="RH288_003419"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HDV4032445.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
                     AAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRK
                     QYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTP
                     RGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMS
                     TPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIK
                     ELLEDPTRLLLDV"
     gene            7940..9106
                     /gene="sucC"
                     /locus_tag="RH288_003420"
     CDS             7940..9106
                     /gene="sucC"
                     /locus_tag="RH288_003420"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HDV4032446.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIG
                     AVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK"
     gene            9106..9975
                     /gene="sucD"
                     /locus_tag="RH288_003421"
     CDS             9106..9975
                     /gene="sucD"
                     /locus_tag="RH288_003421"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HDV4032447.1"
                     /translation="MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKG
                     GTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEA
                     AAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKTVLK"
     gene            complement(10079..10801)
                     /gene="mngR"
                     /locus_tag="RH288_003422"
     CDS             complement(10079..10801)
                     /gene="mngR"
                     /locus_tag="RH288_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-D-glycerate transport/metabolism system
                     transcriptional repressor MngR"
                     /protein_id="HDV4032448.1"
                     /translation="MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRV
                     TVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIF
                     EVIPADDFLQQQLQITPQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENS
                     KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEY
                     SRNAFNTDDYKFTLIAQRKSSR"
     gene            10970..12886
                     /gene="mngA"
                     /locus_tag="RH288_003423"
     CDS             10970..12886
                     /gene="mngA"
                     /locus_tag="RH288_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDV4032449.1"
                     /translation="MNLTTLTHRDALCLNARFTSREEAIHALTQRLAALGKISSTEQF
                     LEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVV
                     LLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDKGGTQPSASF
                     SNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNS
                     ATACIFAAEVAIKESERFNGIPALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDT
                     QPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMY
                     RKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAG
                     YLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNG
                     LSGSNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFT
                     VTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTG
                     AIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLMWRRH
                     AVKHGNYLTDGVMP"
     gene            12904..15537
                     /gene="mngB"
                     /locus_tag="RH288_003424"
     CDS             12904..15537
                     /gene="mngB"
                     /locus_tag="RH288_003424"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDV4032450.1"
                     /translation="MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQD
                     NEYKYYVLDGQTAILEDYFAVKPENKDRVKKQVEAGKLIIGPWYTQTDTTIVSAESIV
                     RNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
                     TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLP
                     NGHDQMPLQQNIFEVMDKLREIYPQRKFVMSRFEEVFEKIEAQRDNLATLKGEFIDGK
                     YMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILK
                     NHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNL
                     MPWPREEVINTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPF
                     MEFDIQINQIVPSMGYRTLYIEANQPGNVIAAKSDAEGILENAFWQIALNEDGSLQLV
                     DKDSGVRYDRVLQIEESSDDGDEYDYSPAKEEWVITAANAKPQCDIIHEAWQSRAVIR
                     YDMAVPLNLSERSARQSTGRVGGVLVVTLSHNSRRIDVDINLDNQADDHRLRVLVPTP
                     FNTDSVLADTQFGSLTRPVNDSAMNNWQQEGWKEAPVPVWNMLNYVALQEGRNGMAVF
                     SEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVPDSQLRGLLSC
                     RLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDVMKLNKAGFNVPESYSLLKMPP
                     VGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQ
                     GSNLSGPFLPGQSRTFSYRLA"
BASE COUNT         3773 a         3969 c         4344 g         3700 t
ORIGIN      
        1 caggataaaa cccgacaaac tatatgtagg ttaattgtaa tgattttgtg aacggcctat
       61 actgccgcca ggtctccgga acaccctgca atcccgagcc acccagcgtt gtaacgtgtc
      121 gttttcgcat ctggaagcag tgttttgcat gacgcgcagt tatagaaagg acgctgtctg
      181 acccgcaagc agaccggagg aaggaaatcc cgacgtctcc aggtaacaga aagttaacct
      241 ctgtgcccgt agtccccagg gaataataag aacagcatgt gggcgttatt catgataaga
      301 aatgtgaaaa aacaaagacc tgttaatctg gacctacaga ccatccggtt ccccatcacg
      361 gcgatagcgt ccattctcca tcgcgtttcc ggtgtgatca cctttgttgc agtgggcatc
      421 ctgctgtggc ttctgggtac cagcctctct tcccctgaag gtttcgagca agcttccgcg
      481 attatgggca gcttcttcgt caaatttatc atgtggggca tccttaccgc tctggcgtat
      541 cacgtcgtcg taggtattcg ccacatgatg atggattttg gctatctgga agaaacattc
      601 gaagcgggta aacgctccgc caaaatctcc tttgttatta ctgtcgtgct ttcacttctc
      661 gcaggagtcc tcgtatggta agcaacgcct ccgcattagg acgcaatggc gtacatgatt
      721 tcatcctcgt tcgcgctacc gctatcgtcc tgacgctcta catcatttat atggtcggtt
      781 ttttcgctac cagtggcgag ctgacatatg aagtctggat cggtttcttc gcctctgcgt
      841 tcaccaaagt gttcaccctg ctggcgctgt tttctatctt gatccatgcc tggatcggca
      901 tgtggcaggt gttgaccgac tacgttaaac cgctggcctt gcgcctgatg ctgcaactgg
      961 tgattgtcgt tgctctggtg gtttacgtga tttatggatt cgttgtggtg tggggtgtgt
     1021 gatgaaattg ccagtcagag aatttgatgc agttgtgatt ggtgccggtg gcgcaggtat
     1081 gcgcgcggcg ctgcaaattt cccagagcgg tcaaacctgt gcgctgctct ctaaagtctt
     1141 cccgacccgt tcccataccg tttctgcgca aggcggcatt accgttgcgc tgggtaatac
     1201 ccatgaagat aactgggaat ggcatatgta cgacaccgta aaaggttcgg actatatcgg
     1261 tgaccaggac gcgattgaat atatgtgtaa aaccgggccg gaagcgattc tggaactcga
     1321 acacatgggc ctgccgttct cgcgtcttga tgatggtcgt atctatcaac gtccgtttgg
     1381 cggtcagtcg aaaaacttcg gcggcgagca ggcggcacgc actgcggcag cagctgaccg
     1441 taccggtcac gcactgttgc atacccttta tcagcagaac ctgaaaaacc acaccactat
     1501 tttctccgag tggtatgcgc tggatctggt gaaaaaccag gatggcgcgg tggtgggttg
     1561 tactgcactg tgcatcgaaa ctggtgaagt ggtttatttc aaagcccgcg ctaccgtgct
     1621 ggcgactggc ggggcagggc gtatttatca gtccaccact aacgcccaca ttaacactgg
     1681 cgacggcgtc ggcatggcta tccgcgcagg cgtaccggtg caggatatgg aaatgtggca
     1741 gttccacccg accggtattg ccggtgcggg cgtactggtc accgaaggtt gccgtggtga
     1801 aggcggttat ctgctgaaca aacatggcga acgctttatg gagcgttatg cgccgaacgc
     1861 caaagacctg gcgggccgtg acgtggtggc gcgttccatc atgattgaaa tccgtgaagg
     1921 tcgcggctgt gatggtccgt gggggccaca tgcgaaactg aaactcgacc acctgggtaa
     1981 agaagttctc gaatcccgtc tgccgggtat tctggaactc tcccgtacct tcgctcacgt
     2041 tgatccggtg aaagagccga ttccggttat cccaacctgt cactacatga tgggtggtat
     2101 tccgaccaaa gtgaccggtc aggcgctgac ggtgaacgag aaaggcgaag atgtggttgt
     2161 tccggggctg tttgccgttg gtgaaatcgc ttgtgtatcg gtacacggcg ctaaccgtct
     2221 gggcggcaac tcgctgctgg acctggtggt ctttggtcgc gcagcgggtc tgcatctgca
     2281 agagtctatc gccgagcagg gcgcattgcg cgatgccagc gagtctgatg ttgaagcatc
     2341 tctggatcgt ctgaaccgct ggaacaataa tcgtaacggt gaagatccgg tggcgattcg
     2401 taaagcgctg caagaatgta tgcagcataa cttctcggtc ttccgtgaag gtgatgcgat
     2461 ggcgaaaggg cttgagcagt tgaaagttat ccgcgagcgt ctgaaaaatg cccgtctgga
     2521 tgacacttcc agcgagttca acacccagcg cgttgagtgc ctggaactgg ataacctgat
     2581 ggaaacggcg tatgcaacgg ctgtttctgc caacttccgt accgaaagcc gtggcgcgca
     2641 tagccgcttc gacttcccgg atcgtgatga tgaaaactgg ctgtgccact ccctgtatct
     2701 gccagagtcg gaatccatga cgcgccgaag cgtcaacatg gaaccgaaac tgcgcccggc
     2761 attcccgccg aagattcgta cttactaatg cggagacagg aaaatgagac tcgagttttc
     2821 aatttatcgc tataacccgg atgttgatga tgctccgcgt atgcaggatt acaccctgga
     2881 agcggaagaa ggtcgcgaca tgatgttgct ggatgcgctt atccagctga aagagaaaga
     2941 tcccagcctg tcgttccgcc gctcctgccg tgaaggtgtg tgcggttccg acggtctgaa
     3001 catgaacggc aagaatggtc tggcctgtat taccccgatt tcggcactca accagccggg
     3061 caagaagatt gtgattcgcc cgctgccagg tttaccggtg atccgcgatt tggtggtaga
     3121 catgggacaa ttctatgcgc aatatgagaa aattaagcct tacctgttga ataatggaca
     3181 aaatccgcca gctcgcgagc atttacagat gccagagcag cgcgaaaaac tcgacgggct
     3241 gtatgaatgt attctctgcg catgttgttc aacctcttgt ccgtctttct ggtggaatcc
     3301 cgataagttt atcggcccgg caggcttgtt agcggcatat cgtttcctga tcgatagccg
     3361 tgataccgag actgacagcc gcctcgacgg tttgagcgat gcattcagtg tattccgctg
     3421 tcacagcatc atgaactgcg tcagtgtatg tccgaagggg ctgaacccga cgcgcgccat
     3481 cggccatatc aagtcgatgt tgttgcaacg taatgcgtaa ttaaatgttg atgccgggga
     3541 aatcccccgg ctattcagga aatctttaaa aactgcccct gacactaaga cagtttttaa
     3601 aggttccttc gcgagccact acgtagacaa gagctcgcaa gtgaaccccg gcacgcacat
     3661 cactgtgcgt ggtagtatcc acggcgaagt aagcataaaa aagatgctta agggatcacg
     3721 atgcagaaca gcgctttgaa agcctggttg gactcttctt acctctctgg cgcaaaccag
     3781 agctggatag aacagctcta tgaagacttc ttaaccgatc ctgactcggt tgacgctaac
     3841 tggcgttcga cgttccagca gttacctggt acgggagtca aaccggatca attccactct
     3901 caaacgcgtg aatatttccg ccgcctggcg aaagacgctt cacgttactc ttcaacgatc
     3961 tccgaccctg acaccaatgt gaagcaggta aaagtcctgc agctcattaa cgcataccgc
     4021 ttccgtggtc accagcatgc gaatctcgat ccgctgggac tgtggcagca agataaagtg
     4081 gccgatctgg atccgtcttt ccacgatctg accgaagcag acttccagga gaccttcaac
     4141 gtcggttcat ttgccagcgg caaagaaacc atgaaactcg gcgagctgct ggaagccctc
     4201 aagcaaacct actgcggccc gattggtgcc gagtatatgc acatcaccag caccgaagaa
     4261 aaacgctgga tccaacagcg tatcgagtct ggtcgcgcga ctttcaatag cgaagagaaa
     4321 aaacgcttct taagcgaact gaccgccgct gaaggccttg aacgttacct cggcgcaaaa
     4381 ttccctggcg caaaacgctt ctcgctggaa ggcggtgacg cgttaatccc gatgcttaaa
     4441 gagatgatcc gccacgctgg caacagcggc acccgcgaag tggttctcgg gatggcgcac
     4501 cgtggtcgtc tgaacgtgct ggtgaacgtg ctgggtaaaa aaccgcaaga cttgttcgac
     4561 gagttcgccg gtaaacataa agaacacctc ggcacgggtg acgtgaaata ccacatgggc
     4621 ttctcgtctg acttccagac cgatggcggc ctggtgcacc tggcgctggc gtttaacccg
     4681 tctcaccttg agattgtaag cccggtagtt atcggttctg ttcgtgcccg tctggacaga
     4741 cttgatgagc cgagcagcaa caaagtgctg ccaatcacca tccacggtga cgccgcagtg
     4801 accgggcagg gtgtggttca ggaaactctg aacatgtcga aagcgcgtgg ttatgaagtt
     4861 ggcggtacgg tacgtatcgt tatcaacaac caggttggtt tcaccacctc taatccgctg
     4921 gatgctcgtt ctacaccgta ctgtactgat atcggtaaga tggttcaggc accgattttc
     4981 cacgttaacg cggatgatcc ggaagccgtt gcctttgtga cccgtctggc gctcgatttc
     5041 cgtaacacct ttaaacgtga tgtcttcatc gacctggtgt gctaccgccg tcacggccac
     5101 aacgaagccg acgagccgag cgcaacccag ccgctgatgt atcagaaaat caaaaaacat
     5161 ccgacgccgc gcaaaatcta tgctgacaag ctggagcagg aaaaagtggc gacgctggaa
     5221 gatgccaccg agatggttaa cctgtaccgc gatgcgctgg atgctggcga ttgcgtagtg
     5281 gcagagtggc gtccgatgaa catgcactct ttcacctggt cgccgtatct caaccacgaa
     5341 tgggacgaag agtacccgaa caaagttgag atgaagcgcc tgcaggaact ggctaaacgc
     5401 atcagcacgg tgccggaagc ggttgaaatg cagtctcgcg ttgccaaaat ttatggcgat
     5461 cgccaggcga tggctgccgg tgagaaactg ttcgactggg gcggcgcgga aaacctcgct
     5521 tacgccacgc tggttgacga aggcattccg gttcgcctgt cgggtgaaga ctccggtcgc
     5581 ggtaccttct tccaccgcca cgcggtgatc cacaaccagt ctaacggttc cacttacacg
     5641 ccgctgcaac acatccataa cggccagggc gcgttccgtg tctgggactc cgtactgtct
     5701 gaagaagcag tgctggcgtt tgaatacggt tatgccaccg cagaaccacg cactctgact
     5761 atctgggaag cgcagttcgg tgacttcgcc aacggtgcgc aggtggttat cgaccagttc
     5821 atctcctctg gcgaacagaa atggggccgg atgtgtggtc tggtgatgtt gctgccgcac
     5881 ggttatgaag ggcaggggcc ggagcactcc tccgcgcgtc tggaacgtta tctgcaactt
     5941 tgtgctgagc aaaacatgca ggtgtgcgta ccgtctaccc cggcacaggt ttaccacatg
     6001 ctgcgtcgtc aggcgctgcg cgggatgcgt cgtccgctgg tcgtgatgtc gccgaaatcc
     6061 ctgctgcgtc atccgctggc ggtttccagc ctcgaagaac tggcgaacgg caccttcctg
     6121 ccagccatcg gtgaaatcga cgagcttgat ccgaagggtg tgaagcgcgt agtgatgtgt
     6181 tctggtaagg tttattacga cctgctggaa caacgtcgta agaacaatca acacgatgtc
     6241 gccattgtgc gtatcgagca actctacccg ttcccgcata aagcgatgca ggaagtgttg
     6301 cagcagtttg ctcacgtcaa ggattttgtc tggtgccagg aagagccgct caaccagggc
     6361 gcatggtact gcagccagca tcatttccgt gaagtgattc cgtttggggc ttctctgcgt
     6421 tatgcaggcc gcccggcctc cgcctctccg gcggtagggt atatgtccgt tcaccagaaa
     6481 cagcaacaag atctggttaa tgacgcgctg aacgtcgaat aaataaagga tacacaatga
     6541 gtagcgtaga tattctggtc cctgacctgc ctgaatccgt agccgatgcc accgtcgcaa
     6601 cctggcataa aaaacccggc gacgcagtcg tacgtgatga agtgctggta gaaatcgaaa
     6661 ctgacaaagt ggtactggaa gtaccggcat cagcagacgg cattctggat gcggttctgg
     6721 aagatgaagg tacaacggta acgtctcgtc agatccttgg tcgcctgcgt gaaggcaaca
     6781 gcgccggtaa agaaaccagc gccaaatctg aagagaaagc gtccactccg gcgcaacgcc
     6841 agcaggcgtc tctggaagag caaaacaacg atgcgttaag cccggcgatc cgtcgcctgc
     6901 tggctgaaca caatctcgac gccagcgcca ttaaaggcac cggtgtgggt ggtcgtctga
     6961 ctcgtgaaga tgtggaaaaa catctggcga aagccccggc gaaagagtct gctccggcag
     7021 cggctgctcc ggcggcgcaa ccggctctgg ctgcacgtag tgaaaaacgt gtcccgatga
     7081 ctcgcctgcg taagcgtgtg gcagagcgtc tgctggaagc gaaaaactcc accgccatgc
     7141 tgaccacgtt caacgaagtc aacatgaagc cgattatgga tctgcgtaag cagtacggtg
     7201 aagcgtttga aaaacgccac ggcatccgtc tgggctttat gtccttctac gtgaaagcgg
     7261 tggttgaagc cctgaaacgt tacccggaag tgaacgcttc tatcgacggc gatgacgtgg
     7321 tttaccacaa ctatttcgac gtcagcatgg cggtttctac gccgcgcggc ctggtgacgc
     7381 cggttctgcg tgatgtcgat accctcggca tggcagacat cgagaagaaa atcaaagagc
     7441 tggcagtcaa aggccgtgac ggcaagctga ccgttgaaga tctgaccggt ggtaacttca
     7501 ccatcaccaa cggtggtgtg ttcggttccc tgatgtctac gccgatcatc aacccgccgc
     7561 agagcgcaat tctgggtatg cacgctatca aagatcgtcc gatggcggtg aatggtcagg
     7621 ttgagatcct gccgatgatg tacctggcgc tgtcctacga tcaccgtctg atcgatggtc
     7681 gcgaatccgt gggcttcctg gtaacgatca aagagttgct ggaagatccg acgcgtctgc
     7741 tgctggacgt gtagtagttt aagtttcacc tgcactgtag accggataag gcattatcgc
     7801 cttatccgac aagcgatgcc tgatgtgacg tttaacgtgt cttatcaggc ctacgggtga
     7861 ccgacaatgc ccggaagcga tacgaaatat tcggtctacg gtttaaaaga taacgattac
     7921 tgaaggatgg acagaacaca tgaacttaca tgaatatcag gcaaaacaac tttttgcccg
     7981 ctatggctta ccagcaccgg tgggttatgc ctgtactact ccgcgcgaag cagaagaagc
     8041 cgcttcaaaa atcggtgccg gtccgtgggt agtgaaatgt caggttcacg ctggtggccg
     8101 cggtaaagcg ggcggtgtga aagttgtaaa cagcaaagaa gacatccgtg cttttgcaga
     8161 aaactggctg ggcaagcgtc tggtaacgta tcaaacagat gccaatggcc aaccggttaa
     8221 ccagattctg gttgaagcag cgaccgatat cgctaaagag ctgtatctcg gtgccgttgt
     8281 tgaccgtagt tcccgtcgtg tggtctttat ggcctccacc gaaggcggcg tggaaatcga
     8341 aaaagtggcg gaagaaactc cgcacctgat ccataaagtt gcgcttgatc cgctgactgg
     8401 cccgatgccg tatcagggac gcgagctggc gttcaaactg ggtctggaag gtaaactggt
     8461 tcagcagttc accaaaatct tcatgggcct ggcgaccatt ttcctggagc gcgacctggc
     8521 gttgatcgaa atcaacccgc tggtcatcac caaacagggc gatctgattt gcctcgacgg
     8581 caaactgggc gctgacggca acgcactgtt ccgccagcct gatctgcgcg aaatgcgtga
     8641 ccagtcgcag gaagatccgc gtgaagcaca ggctgcacag tgggaactga actacgttgc
     8701 gctggacggt aacatcggtt gtatggttaa cggcgcaggt ctggcgatgg gtacgatgga
     8761 catcgttaaa ctgcacggcg gcgaaccggc taacttcctt gacgttggcg gcggcgcaac
     8821 caaagaacgt gtaaccgaag cgttcaaaat catcctctct gacgacaaag tgaaagccgt
     8881 tctggttaac atcttcggcg gtatcgttcg ttgcgacctg atcgctgacg gtatcatcgg
     8941 cgcggtagca gaagtgggtg ttaacgtacc ggtcgtggta cgtctggaag gtaacaacgc
     9001 cgaactcggc gcgaagaaac tggctgacag cggcctgaat attattgcag caaaaggtct
     9061 gacggatgca gctcagcagg ttgttgccgc agtggagggg aaataatgtc cattttaatc
     9121 gataaaaaca ccaaggttat ctgccagggc tttaccggta gccaggggac tttccactca
     9181 gaacaggcca ttgcatacgg cactaaaatg gttggcggcg taaccccagg taaaggcggc
     9241 accacccacc tcggcctgcc ggtgttcaac accgtgcgtg aagccgttgc tgccactggc
     9301 gctaccgctt ctgttatcta cgtaccagca ccgttctgca aagactccat tctggaagcc
     9361 atcgacgcag gcatcaaact gattatcacc atcactgaag gcatcccgac gctggatatg
     9421 ctgaccgtga aagtgaagct ggatgaagca ggcgttcgta tgatcggccc gaactgccca
     9481 ggcgttatca ctccgggtga atgcaaaatc ggaatccagc ctggtcacat tcacaaaccg
     9541 ggtaaagtgg gtatcgtttc ccgttccggt acactgacct atgaagcggt taaacagacc
     9601 acggattacg gtttcggtca gtcgacctgt gtcggtatcg gcggtgaccc gatcccgggc
     9661 tctaacttta tcgacattct cgaaatgttc gaaaaagatc cgcagaccga agcgatcgtg
     9721 atgatcggtg agatcggcgg tagcgctgaa gaagaagcag ctgcgtacat caaagagcac
     9781 gttaccaagc cagttgtggg ttacatcgct ggtgtgactg cgccgaaagg caaacgtatg
     9841 ggccacgcgg gtgccatcat tgccggtggg aaagggactg cggatgagaa attcgctgct
     9901 ctggaagccg caggcgtgaa aaccgttcgc agcctggcgg atatcggtga agcactgaaa
     9961 actgttctga aataaatatc tgtaataaga aatagccctc gccgcttccc tctacaggaa
    10021 tggcgaaggg ctgtcggttt cgacatggtt ggccatcgta tgatggcctt ttttgtgctt
    10081 atcgcgatga ttttcgctgc gctatcaggg taaatttata gtcatcggta ttaaaagcgt
    10141 tgcggctata ttcaaacacc cgaccatcaa ctaaatatcc acgcgatact ttttcaagaa
    10201 tcggctttgt ctggctgata ttaagcagac ggctcatctc ttcggttggc atcagaggaa
    10261 tgatttcctg ttcgctacga tcgataacca ttttcttcac ttcttcgata aagtgatatt
    10321 tcgaattttc catgacctgc caggtgagat ccgggaacaa cgcaagcggc atccaggttt
    10381 cttccagcgc cattggcttt tgcttgcgat agcgcacgcg cttcacatgc cacacacgat
    10441 cctgcggggt gatttgtagc tgttgctgaa gaaaatcgtc agccggaatc acttcgaata
    10501 tcagaacttc actgtgtgta tcgacgtgac ggtccgacag tttttcatca aaactggtta
    10561 actgaaaaat atcgtaattg acccgctctt ctttgacgta agtcccgctg ccctgaatgc
    10621 tttcgaggat ctgctgctcg actagctggc gcaaagcctg acgcaccgta acccggctga
    10681 cgccaaactc tgtttgtagc gctgattcag tgggtaacgc atcgccaggt ttaagctcgc
    10741 cacgcgcaat ttgttcacga atgcgatcgg caatctgccg gtataagggc ttgtgtccca
    10801 tttttagtat ctcattaata cgaatttaac cattatgccc gataaattca tcctgtaaat
    10861 aatacaaata caatacaaat aatttcaatc aagtgaaatt gatcacataa tggtattgtt
    10921 ttatcgggca cactggcgcg actataaaaa cgatcaagtg aggatcatga tgaatctgac
    10981 gactctgacc caccgcgatg cgttgtgtct gaatgcgcgc tttaccagcc gtgaagaggc
    11041 catccacgcg ttgactcaac gtcttgctgc tctggggaaa atttccagta ctgagcaatt
    11101 tctggaagaa gtgtatcgcc gtgaaagcct tggcccgacc gccttaggtg aagggttggc
    11161 tgtgccgcat ggcaaaactg ctgcggtaaa agaagcggcg tttgcggtcg ccacactcag
    11221 cgagccgctt cagtgggaag gcgttgatgg cccggaagca gttgatttag tggtgctgct
    11281 ggcgattccc cccaatgaag cgggtactac gcatatgcaa ctgctgacag cgctgaccac
    11341 gcgccttgcg gatgatgaga ttcgggcgcg tatacagtcg gcgacgacgc ctgatgagtt
    11401 gctctcggcg ctggatgaca agggaggcac gcaaccttct gcctcttttt ccaacgcgcc
    11461 aactatcgtc tgcgtaacgg cctgtccggc gggtattgct cacacctata tggctgcgga
    11521 atatctggaa aaagccggac gcaaactcgg cgtaaatgtt tacgttgaaa aacaaggcgc
    11581 taacggcatt gaagggcgtt taacggcgga tcaactcaat agtgcaaccg cctgtatttt
    11641 tgcggctgaa gtcgccatca aggagagtga gcgttttaat ggcattcccg cgctttcagt
    11701 gcctgttgcc gagccgattc gccatgcaga agcgttgatc caacaagcgc ttaccctcaa
    11761 gcgtagcgat gagacgcgta ccgtacagca agatacgcaa ccggtgaaaa gtgtcaaaac
    11821 ggagctgaaa caggcactgt tgagcggaat ctcttttgcc gtaccgttga ttgtcgcggg
    11881 gggcacggtg ctggcggtcg cggtattact gtcgcaaatc ttcgggctac aagatctgtt
    11941 taatgaagaa aactcctggc tgtggatgta ccgcaagctg ggcggcgggc tgctcggaat
    12001 tttgatggta ccggtgctcg cggcctatac cgcctattct ctggcagata aaccggcgtt
    12061 agcgccaggc tttgcggctg gacttgccgc caacatgatc ggctccgggt ttctcggcgc
    12121 ggtcgttggc ggattgatag ccggttactt gatgcgctgg gtgaaaaatc acttgcgtct
    12181 tagcagtaaa ttcaatggat tcctgacttt ttatctctac ccggtgctcg gtacgttggg
    12241 agcgggcagt ctgatgctgt ttgtggtggg ggaacctgtc gcctggatca ataactcgct
    12301 taccgcctgg ctgaacggtc tgtcaggaag taacgcgctg ttgctgggtg ccattctcgg
    12361 ttttatgtgt tcctttgacc ttggagggcc agtgaataaa gccgcttatg cattctgcct
    12421 gggcgcaatg gcgaacggcg tttacggccc gtatgccatt ttcgcctccg tcaaaatggt
    12481 ttcggcattt accgtaaccg cttccacgat gctcgcaccg cgcctgttta aagagtttga
    12541 aattgagacc gggaaatcca cctggctgtt agggctggca ggtattaccg aaggggcgat
    12601 cccgatggcg attgaagatc cgctgcgggt tattggttcg tttgtgctgg gctctatggt
    12661 aacgggcgct attgtcggtg cgatgaatat cggcctttcg acacccggtg ccggcatttt
    12721 ctcgctcttt ttacttcatg ataatggcgc gggcggtgtt atggcggcaa ttggctggtt
    12781 tggcgcggca ttggtggggg ctgcaatctc gactgcaatt ctcctgatgt ggcggcgtca
    12841 cgcggttaag catggcaact atctgactga tggcgtaatg ccataaacaa aaaggaaacg
    12901 acgatgaaag cagtatctcg cgttcacatc accccgcata tgcactggga tcgagagtgg
    12961 tatttcacca ccgaagagtc acgtattctg ctggtcaata atatggaaga gatcctgtgc
    13021 cgactggaac aggacaacga atacaaatat tacgtactcg acgggcaaac ggcgatcctc
    13081 gaagattatt tcgcggtgaa accggaaaac aaagaccgtg tgaagaaaca ggtagaagcc
    13141 ggcaagttga ttatcggccc ctggtatacc cagaccgata ccacgattgt ttctgcggaa
    13201 tccatcgtcc gtaatctgat gtacggaatg cgtgactgcc tcgcgtttgg cgagccgatg
    13261 aaaataggtt atttaccaga ttcctttggc atgtccgggc aactgccgca tatctacaat
    13321 ggatttggca ttacccgcac catgttctgg cgcggatgtt cggagcgcca cggtactgat
    13381 aaaaccgagt ttttgtggca aagcagtgac ggtagcgaag tgacggcgca ggtgctgccg
    13441 ctgggctacg ccatcggtaa gtacttacct gccgacgaaa acggattacg taaacgcctc
    13501 gacagttatt ttgacgtgct ggaaaaagcg tctgtaacca aagagatttt gctgccgaat
    13561 gggcatgacc agatgccatt gcagcaaaat atcttcgaag tgatggataa gctacgtgag
    13621 atctaccctc aacgtaagtt tgtgatgagc cgctttgaag aggtatttga gaagatcgaa
    13681 gcgcagcgag ataatctggc aaccctgaaa ggggaattta ttgatggcaa atatatgcgc
    13741 gtgcatcgca ccatcggttc tacgcgtatg gatatcaaaa ttgcccacgc gcgtattgaa
    13801 aataagattg ttaatctgct ggaaccgctg gcaacactgg cctggacgtt gggttttgaa
    13861 taccaccacg gcttgctgga gaaaatgtgg aaagagatct taaaaaatca tgcccacgac
    13921 agtatcggct gctgctgtag tgacaaagtt catcgcgaaa tcgtcgcccg cttcgaactg
    13981 gctgaagaca tggcggataa tctgattcgt ttctacatgc gcaaaattgc cgacaacatg
    14041 ccgcagagcg acgccgacaa actcgtcctg tttaacctga tgccctggcc gcgtgaagaa
    14101 gttatcaaca ccactgtgcg gctgcgcgcc agccagttta atttgcggga cgatcgcggt
    14161 cagcctgtac cgtattttat tcgccatgcc cgtgagatcg atccaggcct aatcgatcgg
    14221 caaatagttc attacggtaa ttacgatccc tttatggagt ttgatataca gatcaaccag
    14281 attgtccctt ctatgggcta tcgcacgctt tatatcgaag cgaatcagcc tggcaacgta
    14341 attgcggcaa aaagtgacgc tgaagggata ctggaaaatg ctttctggca aattgcgctc
    14401 aatgaggatg gttctctgca actggtagat aaagacagcg gtgtgcgcta tgaccgggta
    14461 ttgcaaattg aagaaagctc tgatgatggt gatgaatatg actattcacc cgcaaaagaa
    14521 gagtgggtaa ttaccgcagc gaacgcgaaa ccgcaatgcg atattattca tgaagcctgg
    14581 cagagcaggg ctgttatccg ctatgacatg gcagtgccgc tcaatttgtc agaacgcagc
    14641 gcccggcaat ccactggcag agtagggggg gtgttggttg tcactcttag tcataacagc
    14701 aggcgtattg atgtggatat caatcttgat aaccaggctg acgatcatcg ccttcgtgtc
    14761 ctggtcccta caccttttaa caccgacagt gttctggcag atacgcagtt tggttcgcta
    14821 acgcgccccg tgaacgacag tgcaatgaac aactggcagc aagaaggctg gaaagaagcg
    14881 ccggttccgg tatggaatat gctcaactat gttgccttac aggaagggcg taacggcatg
    14941 gctgtcttta gcgaagggtt acgtgaattt gaagtcatcg gtgaagagaa gaaaaccttt
    15001 gccattacgt tgctgcgtgg cgtgggctta ctgggcaaag aagatctgct tttaaggcct
    15061 gggcggcctt cgggaattaa aatgccagtc ccggactcac aactacgtgg tctgctttct
    15121 tgtcgcctaa gtttattgag ttataccggt acgccaaccg ccgctggtgt agctcagcag
    15181 gcgcgagcat ggctgactcc agtacagtgt tacaacaaaa tcccatggga tgtgatgaag
    15241 ctcaacaaag ccggattcaa cgtgccggaa agttatagtt tgttgaaaat gcccccagtg
    15301 ggatgcctga taagcgcact taagaaagct gaagaccgac aagaagtgat tttacggctg
    15361 tttaatccgg ctgaatcagc aacctgtgat gcgactgttg ctttcagtcg cgaggtgatt
    15421 tcttgctcag aaacgatgat ggatgaacac attaccaccg aggaaaatca aggttcaaat
    15481 ctatcggggc cttttttacc cggccagtca cggacgttca gttaccggct tgcctgaata
    15541 gcaatcaaac cgaagccaca tatgcgcggc cagattgttg acaaagggcg ctttgttcat
    15601 gccggatacg gcatgaacgc tttattcggt ctacaaaagc aggcaaattc aatatattgc
    15661 agagatgatg tagacactgg caagcgtagc gcatcaggta attttgcgtt tatcttcact
    15721 ctcaagccac gtatatgtgg ctttattttt aacaaaataa taaccctggg tgagttaatt
    15781 ataata
//
LOCUS       DAPHKZ010000104        15762 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.104, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000104 DAPHKZ010000000
VERSION     DAPHKZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15762
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.104"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            290..739
                     /locus_tag="RH288_003425"
     CDS             290..739
                     /locus_tag="RH288_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005035740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032451.1"
                     /translation="MATTLTSECNLLVIPFSAVTNFTTLADYCEHFAETIIECHDLAL
                     KMAPCGRLSTCLALLRPTLGEPIPPHLIDRFSVDVLPDVLPEFTPDADLLCDYCLALA
                     QVLLGRSLLPETETTLTGLLCDLVWYFADGLKAPRWIRTTDGVQPCQ"
     gene            complement(1273..1422)
                     /locus_tag="RH288_003426"
     CDS             complement(1273..1422)
                     /locus_tag="RH288_003426"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032452.1"
                     /translation="MSDGGNMAQAGTGAACGGMLCSVTLPCRWRDQSDASSGAEGKRC
                     VSGAG"
     gene            1646..2530
                     /locus_tag="RH288_003427"
     CDS             1646..2530
                     /locus_tag="RH288_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001587348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase domain-containing protein"
                     /protein_id="HDV4032453.1"
                     /translation="MSKLSSEMKALAKKAGGSFKTVNDRIHITKRFSEHLRALNIQIQ
                     RVEQIKVRHIECYIEERLEQDIGLRTLQNDMAALQAVLRQAGRRQVVEHPRLTNKALG
                     VSGASRNGTRRAITPEHYQQVMEKARTEDAGLAAALEIARLMGLRSQEAVQSSQSLKT
                     WLKAIERGENRLKVVFGTKGGRPRYTTVLDTGAVRKALEKSLLVADRHNGRLIDKPDL
                     KMALESWHKQVIKVGLKGEFSPHSLRYAWAQDAIRHYLAQGFSEKESLALTATDLGHG
                     DGRGRWVKQVYGYRWREE"
     gene            complement(3841..5103)
                     /locus_tag="RH288_003428"
                     /pseudo
     CDS             complement(3841..5103)
                     /locus_tag="RH288_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055676.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
     gene            complement(5266..5341)
                     /locus_tag="RH288_003429"
     tRNA            complement(5266..5341)
                     /locus_tag="RH288_003429"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5306..5308),aa:Asn,seq:gtt)
     gene            complement(5442..6239)
                     /gene="mtfA"
                     /locus_tag="RH288_003430"
     CDS             complement(5442..6239)
                     /gene="mtfA"
                     /locus_tag="RH288_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HDV4032454.1"
                     /translation="MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAE
                     RFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDE
                     WEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
                     RASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSE
                     YFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHRANDTDSFSATNVH"
     gene            6333..6422
                     /locus_tag="RH288_003431"
     tRNA            6333..6422
                     /locus_tag="RH288_003431"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6367..6369,aa:Ser,seq:cga)
     gene            complement(6992..7522)
                     /locus_tag="RH288_003432"
     CDS             complement(6992..7522)
                     /locus_tag="RH288_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416483.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HDV4032455.1"
                     /translation="MNRFSKTQIYLHWITLLFVAITYAAMELRGWFPKGSSTYLLMRE
                     THYNAGIFVWVLMFSRLIIKHRYSDPSIVPPPPAWQMKAASLMHIMLYITFLALPLLG
                     IALMAYSGKSWSFLGFNVSPFVTPNSEIKALIKNIHETWANIGYFLIAAHAGAALFHH
                     YIQKDNTLLRMMPRRK"
     gene            complement(7865..8515)
                     /gene="zinT"
                     /locus_tag="RH288_003433"
     CDS             complement(7865..8515)
                     /gene="zinT"
                     /locus_tag="RH288_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HDV4032456.1"
                     /translation="MAIRLHKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGV
                     FDDANVQNRTLSDWDGVWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYHKGYA
                     TDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPK
                     YIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH"
     gene            complement(8772..9407)
                     /gene="msrQ"
                     /locus_tag="RH288_003434"
     CDS             complement(8772..9407)
                     /gene="msrQ"
                     /locus_tag="RH288_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HDV4032457.1"
                     /translation="MRLTVKQVTWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQ
                     HFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGV
                     NNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAIL
                     APIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSFFNRLRKQVHNKLSL"
     gene            complement(9408..10412)
                     /gene="msrP"
                     /locus_tag="RH288_003435"
     CDS             complement(9408..10412)
                     /gene="msrP"
                     /locus_tag="RH288_003435"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HDV4032458.1"
                     /translation="MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHA
                     DLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAA
                     NAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
                     "
     gene            complement(10521..10934)
                     /gene="hiuH"
                     /locus_tag="RH288_003436"
     CDS             complement(10521..10934)
                     /gene="hiuH"
                     /locus_tag="RH288_003436"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HDV4032459.1"
                     /translation="MLKRYLVLSVVTAAFSLPSLVYAAQQNILSVHILNQQTGKPAAD
                     VTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLES
                     FFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS"
     gene            11067..11738
                     /gene="hprR"
                     /locus_tag="RH288_003437"
     CDS             11067..11738
                     /gene="hprR"
                     /locus_tag="RH288_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HDV4032460.1"
                     /translation="MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDD
                     YALIILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPF
                     SFSELLARVRAQLRQHHALNSTLEISGLRMDSVSQSVSRDNISITLTRKEFQLLWLLA
                     SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSF
                     VAVKK"
     gene            11738..13096
                     /gene="hprS"
                     /locus_tag="RH288_003438"
     CDS             11738..13096
                     /gene="hprS"
                     /locus_tag="RH288_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HprS"
                     /protein_id="HDV4032461.1"
                     /translation="MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTT
                     LINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDSINKIVNRTNVSDGMLN
                     NIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
                     SIIICIVAIILCSVLSPLLIRTGLREIKKLSGVTEALNYNDSREPVEVSALPRELKPL
                     GQALNKMHHALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIA
                     GNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICF
                     KVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIEITSFLDTNGYLNIDVASPGTK
                     IHEPEKLFRRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLNKHNVFRIMLPQ
                     RN"
     gene            complement(13204..14054)
                     /gene="hchA"
                     /locus_tag="RH288_003439"
                     /pseudo
     CDS             complement(13204..14054)
                     /gene="hchA"
                     /locus_tag="RH288_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416476.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
     gene            complement(14647..15705)
                     /locus_tag="RH288_003440"
     CDS             complement(14647..15705)
                     /locus_tag="RH288_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HDV4032462.1"
                     /translation="MKRKVLAMLVPALLVAGAANAAEIYNKNGNKLDLYGKMVGERIL
                     TDRENGEKGDNSQDTSYARVGVKGETQINPELTGYGQFELDLEASNRHNPDQTRLAYA
                     GLSYKDFGSFDYGRNVGVAYDAEAFTDMFVEWGGDSWAGTDLFMTNRTNGVATYRNTD
                     FFGMVEGLNFALQYQGKNEGTGNYKANGDGHGLSVTYTIDGFSFAGAYANSDRTDFQS
                     SDSKGEKAEVWALSTKYDANNVYAAVMYGESHNMNSDDGDVVNKTQNFEAVLQYQFDF
                     GLRPSIGYSYSKALDVAGYKDSDRLNYIEIGTWYYFNKNMNVYTAYQINLLDKSDYVL
                     AHGLNTDDQLAFGIVYQF"
BASE COUNT         4202 a         3529 c         3811 g         4220 t
ORIGIN      
        1 ttgagtttac ctgctttctc caaacctctt gccgcaaatt accgatcatt gtattgttgc
       61 gccgcgtctg caaaatcagg cgtcgggatt ggcatcctgt aatacttcac tgacaacaca
      121 atattttgtg ttgcgtatgg tcacatctca atggtgggat cgggcggggg cgtcgtaaga
      181 cgcgccggtg tcagtgaggc cggtaatgcc aactccgtcc ggtttcacca cccgtgaaat
      241 tggcatttcc ggtggtggag atcatcatca ctcactggag gctgccccta tggcaactac
      301 cctcacttct gaatgcaatt tactcgtcat tcccttcagc gccgttacca acttcaccac
      361 tctggcggat tactgcgagc atttcgctga aacgatcatc gagtgccacg atctggcgct
      421 gaaaatggcg ccctgcggca ggcttagtac ctgtcttgca ctgctgcggc ccacgctggg
      481 cgaaccgatc ccgccgcacc tgatcgaccg ctttagtgtg gatgttcttc ctgatgtttt
      541 accggaattt acccctgatg cagacctgct ctgtgattac tgcctggcgc tggcgcaggt
      601 actgctggga cggtcactgt tgccggaaac cgaaacgacg ctgaccgggt tactgtgcga
      661 tctggtctgg tattttgccg atggtctgaa agctccgcgc tggattcgta ccactgacgg
      721 cgtgcagccc tgtcagtaga ggcagggatg atgcaaccat accggaggac cgatgtgaaa
      781 gtgttagtcc tgataactga accggcagga acactgttac agtaaaacca gactctcccg
      841 gcgctctgcc tgtttttgct ggcagcgcgc cgggagaaga caagcgaagc gcggcagttt
      901 ttccgtcacc aggtaagcaa acatactttc aaacccggaa agagtttttc cttcctgcac
      961 cagaaataat ggcgcagtct cccgcctgca acaaactgcc tccgggcagt ccctttgtcg
     1021 cttcgcgtct gaaagaagcg cctggcattg ccagcatgac atcctttacc ggcgttgatc
     1081 tctgaaaacg ccggggatgc aaaaataccg gcatctgaga ctgacgtaca tatacaccat
     1141 cactgcacca gatacccggc tttacgggct ggcactctgg ctttgccggg ttttatcttc
     1201 tgctgacaac cagcgcctta cattgacggg ctgcggcctg caaagacagc aggctttgct
     1261 gccgcgtgac cgtcaccctg caccagaaac gcaacgttta ccctctgcac cagacgaggc
     1321 gtcactctgg tcgcgccagc gacagggcaa agtgacgctg cacaacatac cgccgcaagc
     1381 cgcgccagtc ccggcctgcg ccatatttcc gccgtctgac atgccctttg gggccgctgt
     1441 cagctcagag taagaggaga aaaagatcga taccgagggg gggctagaag ccccggagat
     1501 acccctgctt cgtcaggcag tctgtaccgc gtacagcctg aaactcccta aacctcaaca
     1561 accagccact ccggcgtgaa ggtatcgttc tggcgcagcc aaacagcaca cgccggagac
     1621 tgtttgttta tgttgcaggg gattcatgag taaattaagc agtgaaatga aggcgctggc
     1681 gaagaaagcg ggcggcagct tcaaaacggt gaatgaccgt atccatatta caaaacggtt
     1741 cagtgaacat ttacgggcgc tgaatatcca gatccagcgg gtggagcaga tcaaggttcg
     1801 ccatatcgaa tgctacattg aggaacggct ggagcaggat attggtttac gaacgctgca
     1861 aaacgatatg gcggcactgc aggccgtgct gagacaggct ggacgcaggc aggtggtgga
     1921 gcatccgcgt ctgaccaata aggcattagg ggtgtcaggc gcttcgcgca acggcacgcg
     1981 ccgcgccatc acgccggaac attaccagca ggtgatggag aaagcccgca ctgaggacgc
     2041 agggctggca gcagcgctgg agattgcgcg gctgatgggg ctgcgttcgc aggaggcggt
     2101 acagagttca cagtcgctga aaacgtggct gaaagccatt gagcgcgggg aaaaccggct
     2161 gaaagtggtg tttggcacca aaggcgggcg tccccgttat acgacagtcc tggatactgg
     2221 cgcagtcagg aaggctctgg aaaagtcctt actggtcgcg gatcgacaca atggcaggct
     2281 gatcgacaag cctgatctca aaatggcgct ggagagctgg cacaaacagg tcattaaggt
     2341 ggggctgaag ggggaatttt cccctcactc cctgcgctat gcctgggcgc aggacgcgat
     2401 ccgccattat ctggcgcagg gattcagcga aaaggaatcc ctggcgctga cggcgacgga
     2461 tctgggtcat ggcgacggtc gcggtcgctg ggtgaaacag gtgtatggat accgctggag
     2521 ggaggaataa ctgaattcat gaatgtcgca aaatagtacg ttactgcgta acgacagcga
     2581 tttatcgtac cctatgttcc ggatctggcg cagggggcga acgggtttat attgtgaaaa
     2641 tatcgttaca gcatgacgaa taaatatcaa cagatcagat tctcctgctt aaccaatata
     2701 gtttgtcgga atattatagt gattacccct gtaatcacac gaaatgctct ctgttaataa
     2761 caggtgtttc aatcattttt accaatacta cagggctggg aaaattttaa aatgtaaatt
     2821 caccggggca tcacattaat tctggcacag ggttatatct gaataattct ctctgtgttt
     2881 ttccgtatcc tgtgacatat attatatggt ctcaggatgc ctcatgattt tataaaaatg
     2941 ctgcgacggt ttttggcata ataacctgct tcatatgaat taagaatctt cggtgcttca
     3001 tgttattttt tgcactttgt gattgttatc ctgtggtgaa aatacagtct ggtgcagact
     3061 gtcatggagc atttccaaat aaactggctg cgccagaaag ggaaagggtc ataaaggtta
     3121 agggggcgat aaggggaaca gcgcctgacc tgaaagggcc aaaaactaaa gggccaggta
     3181 ctggcgcagc actgaacagg tagagcggcg ggacgctggc gcagatagca gattatccag
     3241 gacgggtgca gattattttg tctctgtata gctggtgcag tgataatctg tatcaggaaa
     3301 gattgtccgg tattttatgg cgcatttttg gggatgtatt aagtggtaat tccgtggaaa
     3361 tgtcgattat tgatagcttt tcaccttcca tgattaacat gtgaatcacg gaaggtggct
     3421 gcctgttgaa aacagatgca ttgataggtt tcgcctgaaa tcattggacg ccaaataatt
     3481 tcaggcttat atctgtctgg tttctgaata tctgatgcag ttcttacagg tttcagagta
     3541 tagggtcagg agatattctg gtgcagatat tctggagtat taatttgtat tttcgtgaaa
     3601 atatcccgta ttgataggtt ttcatcttct gtgatttgca ggcaaatcac agaaggtagt
     3661 tatctatcaa taatgcattt attaataggc aatcgactgc aaatattcta ctggaataat
     3721 tttcggtgct tcccaattaa taataacaaa aacagcgaca atacctctca atacaaaaaa
     3781 acagatcccg gtcaatcagg atctgctttt ccggttttaa tgatttacgc tatttctgat
     3841 tcaggctgcc ttatgctgcc gggcataaat gtacggcgca acatacccct cgcggcacac
     3901 atccagataa tccgaccacc actgcatcat ggcctttctg gcctccagat gctctgcttt
     3961 atgcacatat gccgcccgca cgctgttgcg ctcctggtgg ctcatttgcc gctccaccgt
     4021 atcgcgtgac cacaggtccg actccaccag ggcgctacag gccattgccc tgagtctatg
     4081 cccgcagatt tcagttttcg tgtcataccc catcaggcgc agcgcccggt tggttgtgtt
     4141 ttcgctcatt ggcttgtacg gattatgatc gccgggaaac accagatcca gatggccgga
     4201 aagctcctgt atctgtttca gaagggcaat cgcctggcgg gagagcggta cgatatgcgg
     4261 agtacgcatt tttgcgccac gccccgaaaa ccgaactttg tcgatggcct cgcgggtggc
     4321 ggggatggtc cagattttgt gcctgaaatc gatctcgctc cagcgggcga aacgcagttc
     4381 gctggaacgg atgaacaggt gcagtgtcag cacctccgcc agccgggtta actcccggcc
     4441 ctgctgatag tcaccgatgc ggccaagcag ttcggacaac cgctccagcg gtaacgcggg
     4501 gtagtgattc tttacggggg aggagacaac gccatccaga tgctgcgccg gattgctttc
     4561 ggtaagcccc tgctatacgg catagcgcat gatgttgctg agttgctgcc gcgtgcggga
     4621 cgcgacttcc agaaagccct tatcctcaat aaccctcagc agggcagtga aatcctgcgt
     4681 tttaagtttg gcaacgggca aatgaccaac cgccgggaag atatggtttt ccatactggc
     4741 gagaatacgg gcggcataat cagccgacca ttttttgttg gttttgtgcc aggccagcgc
     4801 caccgcttta aagcactttt caggggagca ggcggctttc tctgccatgc gctgctgcgc
     4861 cgggttgata ttctgcgcca gtaacttgcg gataccgtcg cgctgttgcc tggcttctgc
     4921 cagtgagacc agcgggtata cgccaagact gactctggat tcttttccgt tgaaacgata
     4981 tttgagatac cagatgcgcg aaccgcccgg attgacgagc agatacagac cgtgagagtc
     5041 ggagagtttt accggacggg aagaagattt taacttgcgg attttagaat cgtttaaaga
     5101 cattttgggg gtcactccag aatcgaacca aactgacccc agatctgacc accaaattat
     5161 cccgatgcgg agataaaacc agatacgcac cggcaaggat tttcacgcta acttactgaa
     5221 tcgtaaacaa atataaacgt acagataagc atgaaaactt gaatctggct cctctgactg
     5281 gactcgaacc agtgacatac ggattaacag tccgccgttc taccgactga actacagagg
     5341 aatcgtgtga acggggcgca tattacttag cggtaccttg tctgtcaaca ctaaatttca
     5401 taagtcattt caattggtta attaatctgc aaagttgtta attaatgaac attcgtcgcc
     5461 gaaaacgaat ctgtatcatt agcgcgatgc agtctctgca aaggatcttg ttgataaaat
     5521 tggcagaaac gttgccacaa tgaagggaaa cgaggagcaa aaagttctgg ggcgctaaag
     5581 aaatattcag aaagtacggc aaaacattca gcaggatcac tggcagcata agcatcaatg
     5641 ctcgccgcat tctcgccaac caattcgatt tcttcctgaa tgttgttcat tgcagcatga
     5701 agatcgtgtt cccagccagc aacctcacgc aacggaataa agggaactcc gctggcgcga
     5761 tcgccgttac gggtgtccag cttatgagcg acttcatgaa taatcaggtt aaaaccagaa
     5821 gcatcaaaag aatcttgtat atccaaccag ttcaaaacga taggcccttg ctgccagctc
     5881 tgacctgact gaacaatacg ttggttatgc accagaccga tatcgtcttc ccattcatca
     5941 tcgaccacaa atggcgcagg ataaattaag acttcatgaa aaccatccag ccattccagt
     6001 cctaactcca gaacgggtag gcaaaataga agtgctatcc ggcagcttct taatgaatcc
     6061 agttcaaagc cctgtaaagg aacaagccgc ttttgctgta aaaaacgttc ggcaagagtg
     6121 actaatttgc tttgttcctg ttccgtcaga cacgttaaaa gggggatcga tagtgcttcc
     6181 tgccagggaa gggcagtttg atgtgctgat tcttgtactt tccagggcca cttaatcatc
     6241 gttttgctcg caaactcgtc acttgaacaa aattgcacgg acagggactg ttaaaatgcc
     6301 aaatttcctg gcatcatggc aaccatctga acggagagat gccggagcgg ctgaacggac
     6361 cggtctcgaa aaccggagta ggggcaactc taccgggggt tcaaatcccc ctctctccgc
     6421 cactttatca atgacttatc tcccgacttc ccgccttgct tttcctaaac agaacaatcg
     6481 tagaatattc ttgaagggtt agatcgtcac tgttttctgt tcgatactgt gacattcagc
     6541 acttgattcg ctatggatct gacaggaagc tttcgagcga aaatgtgcag ttattcagtc
     6601 gttttcttat cgctcaccat tattctttta gacattcatc ctatgaaact gccgcaaagt
     6661 tggtggtggg aactgaagtt gcgtagagaa ggggtcaata attgagtcaa aaaaggaacg
     6721 cggccgtcag attaaagccg cgggacaaag tccataattt ccaagagttg ttgaatttcc
     6781 cagctttttt gaaagccttt gtatcatact aacaagtaaa aaaggtttaa ataccaaaat
     6841 taacctgtat ttttgataag tcttaccatt gtacgattta cacagtttct gctcctcctt
     6901 gttgatagtg gaaagggtgc attgtgcact tgcgtaaaca tttatgacgc gttgatgtcc
     6961 atagtgcaca tttccttgtc aggggatcga cttatttgcg gcgaggcatc attcgtaaca
     7021 gagtattatc tttctgaatg tagtgatgaa agagtgctgc gccagcgtga gctgcgatta
     7081 aaaagtagcc tatatttgcc caggtttcgt gaatattttt tatcagtgct ttaatttcgc
     7141 tgtttggggt aacaaaggga gacacattga aaccaaggaa actccacgat tttccactgt
     7201 aagccatcaa agcaatcccc agcagaggaa gtgcaaggaa ggttatataa agcatgatgt
     7261 gcattagcga agccgctttc atttgccagg caggtggcgg tggcacaata gaaggatcac
     7321 tataacggtg ttttataatc aggcgtgaaa acattaacac ccaaacgaat atacccgcat
     7381 tgtaatgtgt ttctcgcatc agcagataag tactactacc tttaggaaac cagccacgga
     7441 gttccatcgc ggcataggtt attgcaacga aaagcagcgt tatccaatgt aaataaattt
     7501 gagtttttga gaatcggttc atttttgtag ctcctgtaat tttcacagtc aagctatccc
     7561 acgaacctta aaaattcctt atacagatgt ggttttaaga atttgttatt taaaaaattg
     7621 atagtgcaca ttgtaaccag ccaatataag caatggcgtg agcacaggta tctttctctg
     7681 ttggccgtat tgtgtatgga atccgttatt ggttaactca atgcgggtta gcttattaat
     7741 atacagacac gtcatagtga tgagcgtgtc tgtagttagc ttgcgttcag tggcgtttgt
     7801 ggatggacca gtggcagtta tgatgactta ctaaagcggc atcgaggcgt tatcatgaga
     7861 atactcaatg agacatcatt tcctcgacca cttcttcact actcaactga tatggataat
     7921 acgttggcca gttttccatt tcatttaata aagattgctg tgaatcatta cccataaaaa
     7981 tgtgaaaatg agatgatttt cgtggtgcaa ttatatgatc gctaaattgt atatatttag
     8041 gggctttgct ttcaggatct ttacattcga ataagtaacg aacgcctttc ttgcctgatt
     8101 tataggtgag tattttgtat ccatcgtaat catatttaca ggatgttgtt tcattatttc
     8161 tatggaattc aacaatgccg tcctcaatgc caatcatctc gatatctgtt gcataacctt
     8221 tgtgataata atctttaatt tcagcaaatg ttttagtttt atctgcatcc gctttcttct
     8281 gaaagacggg gtcaagtttg ccactttgca gtaaaggata aacggattgc cagactccat
     8341 cccagtcact gagcgttcgg ttttgtacat tggcatcatc aaaaacacca ttagcagctt
     8401 tttgttcgac ctctgttaag ggtttgccgt gtgagtgatg accatgcgaa aaggcaggag
     8461 cgctaacaat aaagacacct aaagcaacag ccagtttgtg aagacgaatc gccaaaacag
     8521 tttcctccag agtcattgta tatgatgtgt aatgttatat tgtaacatgt gacaaaatgc
     8581 aacaactctt aggagatgag agcatagttt tctcaggtgt acttatctat cttattgaaa
     8641 taaaatgaat tatgttgata atttgaggtt gatgacaaac gaaacataac ctgatgtgat
     8701 ctgcgtaggc cggatagggc gctcgcgccg catccggcag ggataacgcg tactttgtcg
     8761 gcaatatgaa gttatagaga taatttgttg tgaacctgct tgcgtaaccg gttgaaaaag
     8821 gaaagcaact tcttataccg taaggctaaa agcagtaccg ccagcccagc gtagatgagt
     8881 ggctgcggtg aaataatctt cactgaccac aaataatgta ttggggccag gatcgcgaca
     8941 agatagacga agttatgcaa ctgttgccag tgcttgccga gttttcgctg catcgcctgg
     9001 gttgaagtaa acgctaaagc aagcaaaata acccagctga taattcctaa cgttaaataa
     9061 ggccgggtaa ttaactcctt gcctaataac gccagattat tcacgcccag ctccagcaat
     9121 gcgtaactgg ttaaatgcag tgtcgcccag gcaaagcacc ataagcctaa caggcggcga
     9181 gtgcgtatca ataacggctg ttttgcgtag cgtgccagag gtgtgattaa caaggtcgcc
     9241 agcaaaaatt tcagtgcagt gcgaccggta aaatgctgaa tatctttcac cggatcggca
     9301 cccagtccac cgtgattgat cgcccagacc agccagagaa acggcaacaa tccggcaaga
     9361 tgcaggcaaa ctttcagcca tgtcacctgt tttactgtca gacgcattca gaaattctcc
     9421 cgcaaatcca ggccacgata cagcgatgcc acctggtcgg cgtaaccatt aaacagtagc
     9481 gttggctggc gctgtacatc gaggatgccg cctgaaccaa taaatcgttc ggtagcctgt
     9541 gaccagcgtg ggtgatcaac atgcggatta acgttggcgt aaaaaccgta ttcgtcaggc
     9601 gctgccagat tccaggtggt tggcggacgc tcgcgggtca gcttaatact gactatcgat
     9661 ttaatccctt taaagccata tttccacggc acaatcagtc gtaccggcgc gccattttgt
     9721 ggcggtaacg ccttgccata aacacccacg gtcatcagtg tgagcggatg cattgcttcg
     9781 tcgagacgca atccttcgac ataaggatat ttcagcccgc cgccgataaa gcggtcctgc
     9841 tggccaggca tctgttccgg tgcataaatt gtttcgaaag cgacatactt cgcattgctg
     9901 gtgggttcgg caagcgccag caatttgtgc agcggaaaac caatccacgg caccaccatc
     9961 gaccacgctt ccacgcagcg catacgataa atacgctctt ccagcgggaa gcgacgggtt
    10021 aaatcatcgt gatcgagggt caatggtttt gccacttcgc cgctgatttt cagtgtccat
    10081 ggatcggttt tcaggctacc agcattagcg gcgggatcgg ctttatccag cccgaattca
    10141 tagaagttgt tatagccgga aactttatct gctggcgtca gtggcaggtt attttgccag
    10201 gcggcaggct tgctgaactc cagcggtttt ccggcggggg cgggtgggcg atcgttccct
    10261 ttaaaccagc taagcagatc ggcatgcgca gcgtgaggca aagaaagtgc agctgcgctg
    10321 atgcccagtg cttttaacac ctgccgacgc ttcataaaga ataccgactc ggccgtaaca
    10381 tctgattctt ttaaaaattg attctttttc ataagccatc acactttttt gtcgttagcc
    10441 agcaagagcc gtttactgtt aatctgtcag ggagtgtcct ccctaacagt agcagagatc
    10501 tgcttttaca tatttatgca ttaactgcca cgataggttg aatacccata ttggctaagt
    10561 aataaaggca catgataatg ctcgttcact ttattaatat gaaattcaac ggggatctca
    10621 gggaagaaac tttcaagatt ttgtttcttg aaatagtccc cggttttaaa tacgacacgg
    10681 taatcgcccg tagttgcagt ttgctcgggc cacagtgcct taattcgtcc atccttatct
    10741 gttttggcgg tattaagttg taaccagccg ttgtccgctt tcttttcaag agtgactgtc
    10801 acgtcggcag cgggttttcc tgtttgctgg ttcaaaatgt gcacgctaag aatgttttgt
    10861 tgtgcagcat agaccaaaga aggtaatgaa aatgcagccg ttactacgga gagtactaaa
    10921 taacgcttta acatgtttat atccttgtca tgtgaatgag ttttgaggat agcgaaaaag
    10981 cgtccagggt aaccttacag cagcattaca attttgtaat gaaccaggct gtttctataa
    11041 catatgattt atggcatatt attttcatga agattttact tattgaagat aatcaaagga
    11101 cccaggagtg ggtaacgcag gggctttccg aagcgggtta tgtcattgat gccgtttctg
    11161 atggcagaga tgggctttat cttgcgctga aggatgatta tgcattgatc attctggata
    11221 ttatgcttcc gggtatggat ggctggcaga tcttacaaac gttaagaaca gcaaagcaaa
    11281 cccctgttat ttgccttact gcaagggatt ctgtcgatga cagagtcaga gggctggaca
    11341 gtggggcaaa tgattatctg gtaaaacctt tttcattttc tgagttgctg gcaagggttc
    11401 gggcacaatt aaggcaacat cacgctttga attcaacatt agaaatcagc ggcttaagaa
    11461 tggactctgt tagtcaaagt gtgagcaggg acaatatcag tattacactg acgcgcaagg
    11521 agtttcagtt actttggcta ctggcctcca gagctggcga aattataccc agaacggtta
    11581 ttgcgagtga aatttgggga atcaactttg atagtgatac caatacggtg gacgtcgcca
    11641 ttcgcaggct ccgcgcaaaa gttgatgatc cttttcctga aaagctaatt gccacaatcc
    11701 gtgggatggg atattcgttc gtagcggtaa aaaaataatg aaaagattgt ctataaccgt
    11761 ccgtttaacc ttgcttttta tattgctact gtctgttgct ggtgctggaa ttgtctggac
    11821 tctctataat ggcctggcaa gtgagttgaa atggcgcgat gatacaacac tcattaaccg
    11881 gacagcacag atcaagcagt tgttaattga tggggtaaat ccagatacgt tacctgtgta
    11941 ctttaaccgg atgatggatg ttagtcagga tatcttgatc attcatggtg atagcatcaa
    12001 taaaattgtt aaccggacaa atgtcagtga tggcatgtta aataacatac ctgctagtga
    12061 gacaatcagc gcagctggca tttacagaag cattattaat gatacagaga tagatgcttt
    12121 acgaattaat attgatgaag tttcgccatc attaacggtt actgtggcta aattggcttc
    12181 agccagacat aacatgcttg aacagtataa aatcaatagc attataattt gcattgtcgc
    12241 cattatactg tgctcagtat taagtccgct gttaatccga acggggttac gagagatcaa
    12301 aaagttgagt ggtgtaacgg aagcgctgaa ttataacgat agccgggagc ctgttgaggt
    12361 tagcgcatta ccgagagaac taaaacctct tgggcaggcg ttgaataaaa tgcatcatgc
    12421 tttagtcaaa gattttgaac gcctaagtca atttgctgac gatctcgctc atgaacttag
    12481 aacgcccatt aatgcattac tgggtcagaa tcaggttacg ctcagtcaaa ccagaagtat
    12541 cgctgaatat caaaaaacaa ttgccggtaa cattgaagag ctggaaaata tttcgcggtt
    12601 aacagagaac atactgtttc ttgcccgggc agataaaaac aatgttttgg tgaaactgga
    12661 ctcgctttct ctcaataagg aagtcgaaaa tttgttggat tatcttgaat acctttcaga
    12721 cgagaaagag atttgcttta aggtcgagtg caatcagcaa atctttgcgg ataaaatttt
    12781 actgcaacga atgttatcga atcttattgt taatgccatt agatattcac cagaaaaatc
    12841 gcgtattgag ataaccagtt ttcttgatac caacggctat cttaatattg atgtcgccag
    12901 tcctggaacg aaaattcatg agcctgaaaa actcttccgt agattttggc ggggagataa
    12961 ttcgcgtcat tccgtaggtc agggacttgg tctttcttta gtcaaagcga ttgccgaatt
    13021 acatggggga agtgctacgt atcactatct caataagcat aatgtgttcc ggattatgtt
    13081 accgcaaaga aattaacata gggcttcagt acgccataaa tcaaccatga aaaaacgcag
    13141 ccacgtcgtg agtattaacg tggctgcgat tgattatgcg cttacattca tacgtaacag
    13201 ggattaaccc gcataagctg ccagcatttc ctgcgccgcc agtttaccca acgcattcgc
    13261 tgcgaaagga ctgtcgccgg tgagaacttt acggtcctta tgtactcgcc cggtgatgtc
    13321 gtcattaata atgttcatgc ccattttctt cagctcttcg ccgaagtacc aggtgagatg
    13381 acccggcata tagcctatct ctggcgtttg tttgtctgcg gcgtctggga atgcgcaaat
    13441 ggaataacca ttcagtgggt tatcgccgtg gcgaagcgcc agaaaagccg ccgggccgtg
    13501 gcaaagggag ataacaaaac ggtcattttt gattgcccac tgcaaagcag cagctacgtc
    13561 ctggctttct ggtaaaccaa taagtgcgcc atgaccacca ggaacaaaga ttgctgcata
    13621 ttcgctgtca gcgttgaggc tggcgacaac atccgcgagt ttcttcggat tgcggaacaa
    13681 cgatttatgc tgctcaaaga atggcattac tttttcatct ttgtgcggca tagcccagta
    13741 ttcaaacttg gtcatcagac cggaaatggt cgccacttcg aattcgaaac ctgcagcatg
    13801 gagatgatac aacggcagca acgtttcaat cggatggtta ccggtcgaga acagtttccg
    13861 ttatcggttg gcaaataacg ttcgtccgcg gcgatcacca gaattttatg cttaccgcga
    13921 tacggttttg gatagtccac gccatcaaga tcagagacgg gactggtata ttggctaagc
    13981 gaatattctg aagggaagaa tgcattatct tcagcaatat cgacctgcgg atttttactt
    14041 gtttgaacag tcatagtgta ttccttattg ttgcttagtt agggtagtca ctatatttgc
    14101 gactgagctg gtcgctattt ttaaccagtc tggaaaattg agtcaatata tcgaaagcgg
    14161 tagtcggcgg gtgtaagtat gtaatgatga tgctgcactg gtgttgaata ttattcacgc
    14221 caaattttcc ttattgagca acgtcgtcgc aagtggcctc aatgatttta gaccattatc
    14281 aaaggtacgg ggcggcgggg agagatttag tgctgtgaaa tattgtggta ctgatgaata
    14341 tttatatcgc ggattggtag agaaaaagct ttttccatgc actttttttg caaaaatttc
    14401 tatatgggag gcgtgtttgt tgcgggttaa ttcataaaga aatgtatttg gagtgttggc
    14461 tggatgagtc gctggtagat gttattgtgc cagcaggggc agggtaaggt actgtatcga
    14521 tatgctttgg caattgcgcg tgccgcagag ggagataaaa tgccaataaa aaagcctgag
    14581 ttcgatgagg gacgaactca ggctagtgtt aagttttaca gtaacacgcc gcggcgcgtt
    14641 ggctgattag aactggtaga cgataccaaa tgcgagttgg tcgtcggtgt tcagtccatg
    14701 agcgagaaca taatcactct tatcaagcag gttgatctga taagcggtat atacgttcat
    14761 gttcttattg aagtaatacc aggtaccgat ttcaatgtag ttcagacgat cagaatcttt
    14821 gtaacctgct acgtccagtg ctttagaata ggagtaaccg atggatggac gcagaccgaa
    14881 gtcgaactga tattgcagaa cagcttcgaa gttttgtgtt ttgttcacaa catcaccgtc
    14941 gtcggaattc atgttgtgag attcaccgta catcacagca gcatagacgt tgttggcatc
    15001 atattttgtt gacagtgccc aaacttctgc tttttcacct ttactatcac tagactggaa
    15061 atcagtacga tcagagtttg cgtaagcacc agcaaatgag aaaccgtcaa tagtgtaagt
    15121 tacagataaa ccatggccat cgccatttgc tttgtagttg cctgtacctt catttttacc
    15181 ctgatattgc agagcaaaat ttagaccttc aaccatgcca aagaaatctg tgttacgata
    15241 ggttgcaaca ccgttggtac ggttggtcat gaacaggtca gtaccagccc atgaatcacc
    15301 gccccactca acaaacatat cagtaaatgc ttctgcatca tacgcgacac cgacattacg
    15361 accatagtcg aatgaaccaa aatctttgta actcaaacca gcataagcca aacgagtttg
    15421 gtcagggttg tgtctgtttg atgcttccag gtctagttca aactgaccgt aaccagtcaa
    15481 ttcagggttg atctgagttt cacctttcac gcctacacgg gcataagagg tatcttgaga
    15541 attatcgcct ttttcaccat tttcacggtc ggtcagaatg cgctcaccaa ccatcttgcc
    15601 gtacaaatcc agtttattgc catttttatt ataaatttca gccgcatttg ctgcgccagc
    15661 aactaataac gccgggacca gcattgccag aacttttctt ttcattatgt attcccttgt
    15721 gattataatc ttcatgaata tatcaataag tgccgttatc ca
//
LOCUS       DAPHKZ010000105        15497 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.105, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000105 DAPHKZ010000000
VERSION     DAPHKZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15497
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.105"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            27..593
                     /locus_tag="RH288_003441"
     CDS             27..593
                     /locus_tag="RH288_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HDV4032463.1"
                     /translation="MSFTNTPERYGVISAAFHWLSAIIVYGMFALGLWMVTLSYYDGW
                     YHKAPELHKSIGILLMMGLVIRVLWRVISPPPGPLPSYSPMTRLAARAGHLALYLLLF
                     AIGISGYLISTADGKPISVFGWFDVPATLADAGAQADFAGALHFWLAWSVVVLSVMHG
                     FMALKHHFIDKDDTLKRMLGKSSSDYGV"
     gene            597..1172
                     /locus_tag="RH288_003442"
     CDS             597..1172
                     /locus_tag="RH288_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HDV4032464.1"
                     /translation="MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKY
                     PQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
                     IKLKDFNIKTDLGPASQEVDLIISVEGVQQK"
     gene            complement(1214..2266)
                     /locus_tag="RH288_003443"
     CDS             complement(1214..2266)
                     /locus_tag="RH288_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDV4032465.1"
                     /translation="MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDA
                     LYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDD
                     GKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDS
                     HTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNK
                     SRGRLNTTLCIPDPTE"
     gene            2491..3411
                     /gene="lpxL"
                     /locus_tag="RH288_003444"
     CDS             2491..3411
                     /gene="lpxL"
                     /locus_tag="RH288_003444"
                     /EC_number="2.3.1.241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) lauroyltransferase"
                     /protein_id="HDV4032466.1"
                     /translation="MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGL
                     GKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVVKNFESVGMGLMETGMAWFWPDR
                     RIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
                     IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQ
                     AATTTGTWMLARMSGACLVPFVPRRKPDGKGYQLIMLPPECSPPLDDAETTAAWMNKV
                     VEKCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            3583..4809
                     /gene="mdtG"
                     /locus_tag="RH288_003445"
     CDS             3583..4809
                     /gene="mdtG"
                     /locus_tag="RH288_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HDV4032467.1"
                     /translation="MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQL
                     GVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMG
                     LAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPM
                     AGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNP
                     KLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAP
                     RLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT
                     LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAV
                     YSWNSLRRRRIPQVSN"
     gene            4892..5266
                     /locus_tag="RH288_003446"
     CDS             4892..5266
                     /locus_tag="RH288_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309456.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HDV4032468.1"
                     /translation="MTMYATLEEAIDAAREEFLADNPGIDAEDANVQQFNAQKYVLQD
                     GDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGE
                     FQLEPPLDTEEGRAAADEWDER"
     gene            complement(5267..5494)
                     /locus_tag="RH288_003447"
     CDS             complement(5267..5494)
                     /locus_tag="RH288_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HDV4032469.1"
                     /translation="MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDS
                     AWRYVTILDLPFSLVFDTLLLPIDIHHGPYE"
     gene            complement(5667..8210)
                     /gene="mdoH"
                     /locus_tag="RH288_003448"
     CDS             complement(5667..8210)
                     /gene="mdoH"
                     /locus_tag="RH288_003448"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HDV4032470.1"
                     /translation="MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWARED
                     DSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDLWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAK
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRR
                     WGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQ
                     RSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ"
     gene            complement(8203..9738)
                     /gene="mdoG"
                     /locus_tag="RH288_003449"
     CDS             complement(8203..9738)
                     /gene="mdoG"
                     /locus_tag="RH288_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HDV4032471.1"
                     /translation="MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYETPK
                     SNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATA
                     VKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAY
                     KFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPS
                     AWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDED
                     KLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTS
                     IGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            10132..11289
                     /gene="mdoC"
                     /locus_tag="RH288_003450"
     CDS             10132..11289
                     /gene="mdoC"
                     /locus_tag="RH288_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HDV4032472.1"
                     /translation="MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAES
                     SLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLL
                     TLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
                     RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTL
                     FYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETES
                     VITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     TSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR"
     gene            complement(11297..12778)
                     /gene="clsC"
                     /locus_tag="RH288_003451"
     CDS             complement(11297..12778)
                     /gene="clsC"
                     /locus_tag="RH288_003451"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsC"
                     /protein_id="HDV4032473.1"
                     /translation="MMKKTPTSTKDSLPNKEMNDLPRLASAVLPLCSQHPGQCGLFPL
                     EKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDN
                     NTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVV
                     TLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDV
                     PEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTLPLIWAKTRLLSDDPAK
                     GEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTN
                     SLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT
                     FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQYDAAWQLRLDR
                     WGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL"
     gene            complement(12720..13253)
                     /gene="ymdB"
                     /locus_tag="RH288_003452"
     CDS             complement(12720..13253)
                     /gene="ymdB"
                     /locus_tag="RH288_003452"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HDV4032474.1"
                     /translation="MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGP
                     ALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYL
                     NSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
                     EENAHLYERLLTQQGDE"
     gene            complement(13348..13659)
                     /locus_tag="RH288_003453"
     CDS             complement(13348..13659)
                     /locus_tag="RH288_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4032475.1"
                     /translation="MFRPFLNSLMLGSLFFPFIAIAGSTVQGGVIHFYGQIVEPACDV
                     STQSSPVEMNCPQNGSIPGKTYSSKALMSGNVKNAQIASVKVQYLDKQKKLAVMNIEY
                     N"
     gene            complement(13780..14112)
                     /gene="csgC"
                     /locus_tag="RH288_003454"
     CDS             complement(13780..14112)
                     /gene="csgC"
                     /locus_tag="RH288_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HDV4032476.1"
                     /translation="MNTLLLLAALSSQITFNTTQQGDVYTIIPEVTLTQSCLCRVQIL
                     SLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQ
                     WPPSSEKS"
     gene            complement(14171..14626)
                     /gene="csgA"
                     /locus_tag="RH288_003455"
     CDS             complement(14171..14626)
                     /gene="csgA"
                     /locus_tag="RH288_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin major subunit CsgA"
                     /protein_id="HDV4032477.1"
                     /translation="MKLLKVAAIAAIVFSGSALAGVVPQYGGGGNHGGGGNNSGPNSE
                     LNIYQYGGGNSALALQTDARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSAT
                     LDQWNGKNSEMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY"
     gene            complement(14667..15122)
                     /gene="csgB"
                     /locus_tag="RH288_003456"
     CDS             complement(14667..15122)
                     /gene="csgB"
                     /locus_tag="RH288_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HDV4032478.1"
                     /translation="MKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFN
                     QAAIIGQAGTNNSAQLRQGGSKLLAVVAQEGSSNRAKIDQTGDYNLAYIDQAGSANDA
                     SISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR"
BASE COUNT         3857 a         3968 c         3694 g         3978 t
ORIGIN      
        1 ctcgcaaatt cgttttggat gcacttatgt cattcacaaa tacccctgaa cgctatggtg
       61 ttatatctgc ggccttccat tggctaagcg caattattgt ctacggcatg tttgctttag
      121 gtctgtggat ggtcacgctc agttattacg atggctggta tcacaaagca cccgaactgc
      181 ataaaagcat cggtattttg ttaatgatgg ggctggttat tcgcgttctg tggcgtgtca
      241 tatctccacc gccgggtccg ctgccgagtt attcgcccat gactcgtctt gccgcaagag
      301 ctggacatct cgcattgtac ctattgcttt tcgccatcgg catcagcggc tatctgatct
      361 caactgccga tggtaaaccg atcagcgttt ttggctggtt tgacgtcccc gcgacccttg
      421 ccgacgctgg cgcacaggca gactttgccg gtgccctgca tttttggctc gcgtggagcg
      481 tcgtagtact gtccgttatg cacggattta tggccctgaa gcatcatttc atcgataaag
      541 acgacactct gaagcgcatg ctgggaaagt cgtcatctga ctatggagta taaaaaatga
      601 aaaaaagcct gcttggttta accttcgcgt ccctgatgtt ctctgccggt tcagcggttg
      661 ccgccgatta caaaattgac aaagaaggtc agcacgcctt tgttaatttc cgcatccagc
      721 accttggcta tagctggtta tacggcacct ttaaagattt cgacggtact tttacctttg
      781 acgaaaaaaa tccggctgcc gataaagtga atgtgacaat taacaccacc agcgtcgata
      841 ctaatcacgc cgaacgcgat aaacatcttc gcagtgcaga tttcctcaat accgcaaaat
      901 atccacaggc aacattcacc tccaccagcg tgaagaaaga cggtgacgaa ctggatatta
      961 ccggcgatct gacgctgaat ggcgtaacca aacccgtcac gctggaagcg aaattaattg
     1021 gtcagggcga cgacccatgg ggtggtaaac gtgcaggctt cgaggccgaa ggcaaaatta
     1081 agctcaagga cttcaatatc aagacagatt taggtccagc ttctcaggaa gtggatctga
     1141 ttatttcagt ggaaggcgta cagcagaagt aagcgtgaaa tgttgccgga tggcacgcat
     1201 ccggcaatga tatttattct gttggatcag gaatgcacag tgttgtattc agacgtccac
     1261 gagacttatt aaagatctta ttgccatttt cacgtcctgc ccgacggcgt cgctgttctt
     1321 ctggcggtaa cgcgctttct tcgcagcaaa tctcactaca acaacctttg tatttttccg
     1381 cgcatactgg acactgaata aacagcaggt ggcagccatc atttttacag ttggtatggc
     1441 tgtcgcacgg cgcgccgcac tggtggcaat gcgcgataat ctcatccgat atacgttcgc
     1501 ccatccgctc gtcaaaaaca aaatttttgc caataaaacg caccggcaag ccctgctcgc
     1561 gcgccttacg ggcgtattca ataattccgc cctcgatatg ccagactttg ttgaatccgt
     1621 tatgtttcat ccaggcactg gccttttcac aacgaatgcc gccggtgcag tacatgacga
     1681 tttttttatc tttatgtgcc tgcatcatct cgactgcttt tggcagctgc tcacggaagg
     1741 tatctgccgg aatttcgagc gcgttttcaa agtgccccac ttcatactca tagtggttac
     1801 gcatgtcgat aaatagtgca tcgggatcgt caagcatggc gttcacttcc gccgcttgca
     1861 gatactcacc aacattgctg gcatcaaagt gaggatcgtc aataccgtcg gcaacaatgc
     1921 gatcgcgtac cttcatgcgc agtacccaga aggatttccc gtcatcatcc aacgcgatat
     1981 tcaggcgtaa accctctaaa gccgggtcga aggcatagag ctgcgcgcga aatgtttcaa
     2041 cattgctcgc aggtacgctg atttgcgcgt taatgccctc atgcgccaga tacactcgcc
     2101 caaaaacatt cagcgcggta aacagctgat ataaagcgtc acgggtcgcc ttaggatcgg
     2161 cgatgtggaa atacttgtaa aacgaaatgg tggttcgcgg ttcgctctca gccaacattt
     2221 tggcttttag cgcgtcgttg gaaatgcggt tgtgtaacac tggcatggtg tacggttcct
     2281 gcgagatggg aaagtaaaaa tccgcggcat gatatagcaa ttatcgataa ttaacatcca
     2341 cacattttac gctacatttg cgcattaaaa attatttgtt atttacaagc gcggcaattt
     2401 cgcccagtct tcagccacaa attttggttg cgggcgaaaa aatgcgacaa tacatacaat
     2461 tgcccgaata ggttgaaaaa caggattgat atgacgaatc tacccaagtt ctccaccgca
     2521 ctgcttcatc cgcgttattg gttaacctgg ttgggtattg gcgtactttg gttagtcgtg
     2581 caattgccct acccggttat ctaccgcctc ggttgtggat taggaaaact ggcgttacgt
     2641 tttatgaaac gacgcgcaaa aattgtgcat cgcaacctgg aactgtgctt cccggaaatg
     2701 agcgaacaag aacgccgtaa aatggtggtg aagaatttcg aatccgttgg catgggcctg
     2761 atggaaaccg gcatggcgtg gttctggccg gaccgccgaa tcgcccgctg gacggaagtg
     2821 atcggcatgg aacacattcg tgacgtgcag gcgcaaaaac gcggcatcct gttagttggc
     2881 atccattttc tgacactgga gctgggtgcg cggcagtttg gtatgcagga accgggtatt
     2941 ggcgtttatc gcccgaacga taatccactg attgactggc tacaaacctg gggccgtttg
     3001 cgctcaaata aatcgatgct cgaccgcaaa gatttaaaag gcatgattaa agccctgaaa
     3061 aaaggcgaag tggtctggta cgcaccggat catgattacg gcccgcgctc aagcgttttc
     3121 gtcccgttgt ttgccgttga gcaggctgcg accacgaccg gaacctggat gctggcacgg
     3181 atgtccggcg catgtctggt gcccttcgtt ccacgccgta agccagatgg caaagggtat
     3241 caattgatta tgctgccgcc agagtgttct ccgccactgg atgatgccga aactaccgcc
     3301 gcgtggatga acaaagtggt cgaaaaatgc atcatgatgg caccagagca gtatatgtgg
     3361 ttacaccgtc gctttaaaac acgcccggaa ggcgttcctt cacgctatta aatctcccat
     3421 gccggatgct tcagaatggc atccggcatt accacagcaa atccccctga tttagcgata
     3481 aaagctctct ggattgcgcc ccctggaagt cgggcgcata attagtgtgc ttatcttttc
     3541 ttcttatgtt caccgcgcct ggcgcaccaa cagcggattg ctatgtcacc ctgtgaaaat
     3601 gacaccccta taaactggaa acgaaacctg atcgtcgcct ggctaggctg ttttcttacc
     3661 ggtgccgcct tcagtctggt aatgcccttc ttacccctct acgttgagca gcttggcgtt
     3721 accggtcact ccgccctgaa tatgtggtcc ggtattgtct tcagcattac atttttattt
     3781 tcggccatcg cctcaccgtt ttggggtgga ctcgccgacc gtaaaggccg aaaactcatg
     3841 ctattacgct ctgccctcgg catgggcatc gtgatggtgt tgatggggct ggcacaaaat
     3901 atctggcagt ttttgatcct gcgggcgctt cttgggttac ttggcggatt tgtccccaac
     3961 gctaatgctc ttatcgccac acaagtaccg cgtaataaaa gcggctgggc gctgggtacg
     4021 ctctccacag gcggcgttag tggtgcgttg ctcggcccaa tggctggcgg cctgctcgcc
     4081 gatagctacg gcttacgtcc ggtattcttt attaccgcca gtgtgctcat actctgcttt
     4141 ttcgtcaccc tgttttgcat cagagaaaaa ttccagccgg tcagcaaaaa agagatgctg
     4201 cacatgcggg aagtggtgac atcacttaaa aacccgaaac tggtactcag cctgtttgtc
     4261 actacgttaa tcatccaggt ggcgacgggc tcaattgccc ccattctgac gctgtatgtc
     4321 cgcgaactgg cgggtaacgt cagtaacgtc gcctttatca gtggcatgat cgcctcggtg
     4381 ccaggcgtgg cggctctgct aagtgcacca cgactcggca aacttggcga tcgaatcgga
     4441 cccgaaaaga tcctgattac agcgctgatc ttttctgtac tgctgttgat cccaatgtct
     4501 tacgttcaga cgccattgca acttgggatt ttacgttttt tgctcggtgc cgccgatggt
     4561 gcactactcc ccgccgtaca gacactgttg gtttacaact cgagcaacca gatcgccggg
     4621 cgtatcttca gctataacca atcgtttcgt gatattggca acgttaccgg accattgatg
     4681 ggagcagcga tttcagcgaa ctacggtttc agagcggtat ttctcgtcac cgctggcgta
     4741 gtgttattca acgcagtcta ttcatggaac agtctacgtc gtcgtcgaat accccaggta
     4801 tcgaactgat ttttcgcctt tcatacttgc aaaagcggag aatcagctat ccttttccct
     4861 gaaacctcat caactcaaag ggagaatcgt gatgaccatg tacgcaacgc ttgaagaagc
     4921 cattgacgct gcacgcgaag aatttcttgc agacaacccc ggcatcgacg ccgaagatgc
     4981 gaatgtgcaa cagttcaatg cccaaaaata cgttttgcag gacggcgaca tcatgtggca
     5041 agttgagttt tttgccgacg aaggggaaga aggtgaatgt ttacctatgc ttagcggtga
     5101 agccgcgcaa agtgtttttg atggcgacta tgatgagata gagatacgcc aggagtggca
     5161 ggaagagaat acattacatg aatgggacga gggggaattt cagcttgagc caccgctgga
     5221 taccgaggaa ggacgcgcag cagctgatga gtgggatgaa cgttaatcac tcatacgggc
     5281 catgatgaat gtcgatcggc agcagtaaag tatcaaaaac cagagagaat ggcagatcaa
     5341 ggatcgtgac ataacgccag gcggagtcac gcacatccca ttgcacaccg ggataatatt
     5401 ggttgccatg cccctgcccc ggtatagtgc gactaataat gctgccacag ccactcagca
     5461 aggtcaccat gatgctcacc acaattaaac gcatttgata cctctttcgt aaaaaaatac
     5521 cggcataacg ccggtatttt tattggctcg ttgtttttgc cggatgcggc gtgaacgcct
     5581 tatccgaccc acaaagtctt gcaaaatcaa taaattgcag gaacgatgta ggcctgataa
     5641 gcgtagcgca tcaggcaact acgtttttat tgcgaagccg catccggttt acgcaatgcc
     5701 agtggattga gctttatccc ttcgtaataa ctcacccatg aagaatatct ctccggggaa
     5761 ttccagacac ggaaatgcag acgggccatc gtcaccggat cgcttagcag caccaggcga
     5821 cgatcgcgat tcagcttctc tggcgtctcg ttcagcgcct gttcaacgtg gcggtcacgg
     5881 gcgatttcca gcaccttact ggcgcggtga cgcgcggtcg ccattgcggt tgccagagcg
     5941 ttaaatgacg ggttaaacac tgcgtgcata aagccatcat caagggagcg ttgacgattc
     6001 atctcaagga accgatcggt atcaaccagc acctgcggcg gcgaatactc ttccgggatc
     6061 aggaacagtt tccagcgttt ggtgcgcaga ccaacggtgg cacggctgga aatcaccgaa
     6121 acaaacggtg acaggatcaa cgagaagaca atcggtgcca gccagaacag gaaacgcaga
     6181 tccagccacg ccatcccaac agcccacact aaccctaaca gcagctgtga gccgtggcgt
     6241 ttgaacgctt caccccagga agtggagtca tcatcacgct gcggtgaatt ccacaccact
     6301 tcccagccaa ggaacgcgct gacaacgaag accgtatgga acagcatgcg taccggagcc
     6361 agcagcacgg aaaaaagcac ttccagcagc aacgataatg taacgcgcca gaagccgccg
     6421 tattctttcg ttcctttgca ccagataagc aaaatgctca ataacttcgg caggaacaac
     6481 agcaccatgg tcgaagcaaa aagtgcaatc gccagctcag gacgccactg cggccacact
     6541 gggaacaact gccgtggttg caggaagtat tgcggttcgg tcaacgcatg cactacctgc
     6601 aatgcagtag agagcgcgag gaacataaac cacagcggag cggagagata agacatcacg
     6661 cccgtcagga acaccgcacg gtgaaccggg tgcataccct tcaccaggaa cagacggaag
     6721 ttcatcaggt taccgtggca ccatcggcgg tcacgtttta gctcatcaag caagttaggc
     6781 ggcaattctt cataagaacc cgggagatcg taagcaatcc agacccccca acctgcacgg
     6841 cgcatcaacg ccgcttccac gaagtcatgt gacaggattg aaccggcaaa ggaaccttcg
     6901 cccggcagcg gagccagtgc gcagtgctcg ataaacggtt tcacgcggat aatcgcgtta
     6961 tgtccccagt agtgcgactc gccaagttgc cagaagtgca aaccggctgt aaacagtggc
     7021 ccatacacgc gggtcgcgaa ctgctgacag cgcgcataca gcgtatccat accggacgct
     7081 ttcggcgacg actgaatgat cccggcgttc gggttggctt ccatcaggcg caccagcccg
     7141 cacaaacaat caccggtcat taccgagtca gcatccagca ccaccatgta gctgtactgg
     7201 ctgccccagc gacggcagaa gtcatcgata ttaccgcttt tacgcttcac gcggcgacgg
     7261 cggcggcgat agaaaatctg accttcgcca ccgacttcag cgataagctc catccaggct
     7321 ttttgctctg cgacgcagat atccgggtta taactgtcac taagaatgta gacatcaaag
     7381 tgtttggcat tcccggtggc ttttactgat tcccacgttg cacgcaggcc agcaaaaaca
     7441 cggttcacgt cttcgttaca gataggcatg atcaacgccg tgcgatgctc cgggtttaat
     7501 ggttcatcgc caactgttga cgcagatata ctgtatttat cgcgaccaat aagcagttgc
     7561 aggaagccca ttaacgccgt ccagaatccg gcggacaccc aacagaacag taccgcaaag
     7621 aggatcagga taccggtttg cagcatataa ggcagaagct gcataaagga aacccacaaa
     7681 tcctgaccaa ccatatccat aggattaatc agcgcccaac cctgataagg aagaatggtc
     7741 ttcatatacc aggtcgcgac gacagtttgc gcgagcgtca ggatcaacag aatgtaacgg
     7801 cggatggtac cgacggtacg ccacttttgc tcgctctcct gctcttcttt ggtcaaacga
     7861 gccagatagc gcggcgtgac atcgcgtcca cgcaggcgat cccagaaacg gcctaccggg
     7921 ttggtacgcc acgggtcggg aaacatcgag gagcgttttg cttctggcat cgccttcagc
     7981 tgatcgcgcc cttcgtcgtc tttaattaac tgtccatcag caagtgaatc tggccaggct
     8041 tgttccagac gcgcctttac cgagccttgc ggggaatcat cctcccgcgc ccaggtgcgg
     8101 tgttcggcat ccagcgcctg atgaacggcg cggatatcag tcttcggcaa tgccgctttc
     8161 tcgcttgcgg cgatgggcat tgcgtcaatg tactcagttg tcttattcat tggcaggtaa
     8221 ctggtagctc caggtttcac tcaacgtctg atcggcattc accagcgcag cacgcatttc
     8281 agtggttttc ttggcatctt tcactttcac acgcatcacc agacgccagc ctttggtaac
     8341 cgggttatag cgcaccgtgc tttcaactat ctcaccatta tcaccaatgc tggtttgcgc
     8401 tgtgaccggg gtatcctctg gcagtttttt catctctgcg ccggtaaaat cgaccacaaa
     8461 ggcgatagta ccgtcaggct ggcgaatcag gttcgactgc ttcacatccc ccgttgaacg
     8521 acgcgtttgt tgcacccatg cgttatctgg cgcatgcagt ttgtcttcat cacggctgaa
     8581 ggtgatggtg tatttaaagt tcatctcttt acccggctcc ggcagctgat ccggcgtcca
     8641 gtaagcgacg atgttatcgt tggtttcatc gttggttgga atttccacca gctcaacgct
     8701 gcctttaccc cactcccctt tcggagtcac ccatgcgctt ggacggagat cgtaacgatc
     8761 atcgagatct tcaaagcggg agaaatcacg accgcgctgc aacagaccaa agccttgcgg
     8821 gttttccatg gagaagctgc tgaccgctaa atgtttcggg ttattcaacg gacgccagat
     8881 ccattcgcca ttaccggcat ggatagagag accgttagag tcgtgcaact ccggacgata
     8941 gttatttgca ggcgacggtt ggttcggccc aaacaggaac atactggtta acggtgcaac
     9001 ccccagtttg ccgactttat cgcgcagata gattttcgac tgcacatcca caaccgtgtc
     9061 acgccctggc ataaccacga atttgtaagc acctgtcgca cgcggcgagt caagcaatgc
     9121 atagatggtt aaacgtttat cagtcggttt tggacgctcg atccagaact ctttgaagcg
     9181 cggaaattct tcacccgatg gcaaggcggt atcaattgcc aggccgcggg cagaaaggcc
     9241 ataaacctga cctgcaccaa tcacgcggaa atagctggcc ccgagcatgc tgacgatttc
     9301 atcgttttta tctttgctgt tgatcgggta aagcacttta aaaccggcaa agccaaggtc
     9361 ttttaccgta tctttgtcat gctgaacatc gccgaaagtg aaataatccg ggctgtattt
     9421 gattcgtttg actgcggtgg cagtcacttc atttattttg accggggtat cgaagtacat
     9481 accctgatgg tagaactcga gtttgaatgg ggtcttcaga ttgttccagt acgctttgtc
     9541 atgattaaac tggatctgct gatagtccgc gtatttcata tcgcggaaaa cggagggcaa
     9601 gttgcttttg ggcgtctcgt agcctttccc ggctaaagat tgagcttgct ttgcgacatc
     9661 atcaatactg aaagcccagc ttgaagatgt atacagggtt aacattactg cagcactcaa
     9721 ccaacgcatt ttcatcattt gtagtttatg tttcataatt agtaagcact tccccctttg
     9781 tgtgcttata tcgatccgat ctattttaat ggataaccag ccattccgac aacagaatcc
     9841 cggtatcgtt cagcacgctg gctcatggat taagcacctg attgcaaccg ttttcacttt
     9901 ccgtgcttct cctaaagaca gaagcatcga cttcgtgtag ggtttgccag caaatttatt
     9961 tatcaaccgt cttacagacg cttccattct ggttagtggt agcgatgatg ctatgcataa
    10021 aaaccttgaa gcctgcgcct ggcgcggtca ggtcggtgtc actatggcaa caagcctaaa
    10081 ggcataaccc gacagggata agacgaaaaa tccgagatta gttaaccata tatgaaccca
    10141 gtacccgcgc aacgtgaata tttcctcgac tccatccgcg cctggctgat gttgttaggg
    10201 ataccttttc atatttcttt aatctattcg agccatacat ggcatgtgaa tagcgccgaa
    10261 tcatcattgt ggctgaccct ttttaatgac ttcatccact cgttccgcat gcaggtattt
    10321 ttcgttatat ccggctactt ttcctacatg ctttttttac gctatccctt gaaaaaatgg
    10381 tggaaagtac gtgtcgaacg tgtaggtatc ccgatgttaa cagccatccc cctactgaca
    10441 ttaccgcaat ttattatgct gcaatatgtc aaaggaaaag cggaaagttg gcctgggctg
    10501 tcattgtatg acaaatataa tacgttggcc tgggaattaa tatcacacct gtggttttta
    10561 ctggtgttag tggtcatgac gacgctgtgc gtatggatat ttaagcgcat cagaaataat
    10621 ttagaaaatt ctgataaaac gaataaaaaa ttctcgatgg taaaactatc ggtgattttt
    10681 ttatgcctcg gcatcggtta tgcggtaata agaagaacga tttttattgt gtatccgccc
    10741 attctgagta atggcatgtt caattttatt gtcatgcaaa cgctgtttta tttgccgttc
    10801 tttatcctcg gcgcactggc tttcattttc cctcatctta aagccttgtt taccacgccg
    10861 tctcgtggct gtacccttgc agcagcattg gcgtttgtcg cttatttact caaccagcgc
    10921 tatggcagtg gcgatgcctg gatgtacgaa accgagtcgg tgatcaccat ggtcctcggt
    10981 ctgtggatgg tgaatgtggt cttctccttt ggccaccgtt tgcttaactt ccagtcagcg
    11041 cgggtgactt attttgttaa cgcatcgctg tttatctatc tggttcacca cccgttaacg
    11101 ctgtttttcg gcgcatacat tacaccgcac atcacctcca actggcttgg ttttctctgt
    11161 ggcctgatat ttgtagtagg gattgcgata attctgtatg aaattcattt gcgcatcccg
    11221 ttactgaagt ttttgttctc tggtaaaccg gttgttaagc gtgagaacga taaagcacca
    11281 gcccgttaag ccacatttac aataaccatt ccacgggcaa tatcgacgcc agtctgacca
    11341 taacccgctt ccagaaactg gtggcgggtt cttttttgag aataatctct ttctttgcat
    11401 gacgatcaac ccagttgatc cgtccccacc tgtccagacg gagctgccag gccgcatcat
    11461 actggctctg aataaagcgt ttatcaatta actgtgccag cgtttcgctc tctatcacga
    11521 agcccatttc agtattgagc aatgttgaac gcggatcgaa attgaaagag ccgataaaca
    11581 ccgttttacc atcgatgcta aaggttttag catgcaggct ggctccggaa ttaccggtta
    11641 tgccgcgatc gtgtaacgta ctactttgtt cacgcgtcgg cttgagttca tataattcca
    11701 cgccatagcg gagcaatttt ttgcgccagc gcgcgtatcc ggcatggacg acagcaacat
    11761 cgttagcggc aagagaattg gttaggatcg caatctttac cccttttctc accatccgta
    11821 agagttgcgc cacacctgcg cgtgtcggta caaaatagga agagataata tcgatgcgtt
    11881 cactgggtga gcccatgata tcgaacaggc gctgcggtaa cagtgaatgc cgttttgcct
    11941 tgccctcccc tttcgccgga tcatcactta ataaacgtgt cttcgcccag ataagcggca
    12001 atgttccatc aaccagatga tttataaatg gactggattc cattttgcgt aaataacgat
    12061 gcgtcatggc atcgttatgc caggaggcgg gtaactcgat gcgatccgcc atttcaccct
    12121 ccgggacatc cagcacctgc tgtaagggtg aaaccgattt gcaataccag tagcgggcga
    12181 aatcatcggc aacgtcctct accacgggtc ctattgccat gacatctaaa tccgaaaaaa
    12241 gtggctcctc ccctgctcca aaataggcat caccaatatt tcgtcctccc accagggtca
    12301 ccacgccatc gacagtgaaa cttttattgt gcatacggcg attaagacgg gaaaagtcgg
    12361 tgatataacc aagcggacgc agcaagcgaa acgagaaagg attaaaaagc cggacttcaa
    12421 tgcgtggatg actgtcaagc aagcgtaaaa tgtcgtcaag tccgggcgta ttgttgtcgt
    12481 ccagcaacaa acggacgcga acgccacgct ttgctgcggc taacagggcg gaaaacagta
    12541 accgacccga catatcgtcc tgccagatgt aatactgaac atcgagcgta tgctctgcca
    12601 tttcggccag acgataccgg gcggcaaacg catccagact tttctccaga ggaaaaaggc
    12661 cacactgacc gggatgttgc gaacacagtg gcagcaccgc gctcgccagc cggggcaaat
    12721 cattcatctc cttgttgggt aaggagtctt tcgtagaggt gggcgttttc ttcatcataa
    12781 cagacaaagt atacctgttc gggtaaagcg tgacgggtaa taaattctga aacggttttt
    12841 actgcgattt cagccgctgc cgcacgaggg taaccataaa ccccagtact gattgcagga
    12901 aaagccactg acgtatagct gtttgccgcc accagtcgta ggctattgag ataggcatcc
    12961 tgcaaaagct ggtcttcgtt ttgttcacca ccacgccaga ctggcccgac ggtgtgcact
    13021 acggctttag cgggaagatc gcctgcaagc gtaataacgg catgccccgt agggcaatcg
    13081 ccctgctgtt gcctgacttt taaacaagca tccagcaggg ccggacccgc tgcgcgatga
    13141 atggccccat cgacgccgcc gcctcccatt aatgacggat tagccgcatt cacaatcaca
    13201 tcaacggcca gtttggtaat atcaccctgc acaacatgaa tacgcgtttt cataacgcct
    13261 ccttacacct tcttgtttct taagtgtaca gcaggctttt tggttaaatc gcatttttct
    13321 gctcagcaac gtgagttgtt cagaaactta gttatattcg atgttcatta cagccagctt
    13381 tttctgttta tcaagatact gcacttttac tgaggctatt tgcgcgtttt tgacattgcc
    13441 gctcattaac gctttgctgg agtaggtttt gcccggaata gaaccattct gtgggcagtt
    13501 catttctacg ggtgatgact gggtgctgac gtcacatgcc ggttccacaa tttggccata
    13561 aaaatggatc acgccccctt gcacggtgct tccagcaatg gcaataaaag gaaaaaacaa
    13621 actgccgagc ataagagagt ttaaaaaagg tctgaacatt tattctattt cctcaatgat
    13681 tagtcatcct tgagggttgt gttatccata ctttcaggtt ggctgattcg cagcagacca
    13741 ttctctccag attcatctta tgctcgatat ttcaacaaat taagactttt ctgaagaggg
    13801 cggccattgt tgtgataaat gaagtgactg tccatcagaa acagtaacaa ctattttcac
    13861 ccgatcgtcc ggggaaatat ttaaactcaa cttcgtcaaa gcaatgggtt gattagcagg
    13921 caatgaaagg gtcttttctt gcttcgtctg actttgccct gaactgcctt cgcgcaggga
    13981 caatatttgt actctgcaca gacaagattg agtaagagtg acttcaggaa taatggtata
    14041 cacatcccct tgctgggtcg tattaaaggt tatctgactg gaaagtgccg caaggagtaa
    14101 taacgtattc atattcttct cccgaaaaaa aacagggctt gcgccctgtt tctgtaatac
    14161 aaatgatgta ttagtactga tgagcggtcg cgttgttacc aaagccaacc tgagtcacgt
    14221 tgacggagga gttagatgca gtctggtcaa ctgcagcacc gttgccacca ccgaactgtt
    14281 taaccgtcat ttcagaattt ttgccgttcc actgatcaag agtagcgctg ttaccgaagc
    14341 cacgttgggt cagatcgatt gagctgtcat ctgagccctg accaacatct gcaccattac
    14401 cgccgccatg ctgggtaata gtcaagtcag agttacgggc atcagtttgc agagcaagtg
    14461 cagagttacc gccaccgtac tggtaaatgt tcagctcaga atttgggccg ctattattac
    14521 cgccaccacc gtggttaccg ccgccgccgt actgaggaac aacacctgcc agagcgctac
    14581 cggagaatac gattgctgca attgctgcta cttttaaaag tttcatgtaa aacccccatc
    14641 ggattgattt aaaagtcgaa tggaaattaa cgttgtgtca cgcgaatagc catttgcgac
    14701 tgtctctgca ctacaattgc cgttttttga gtaccatact gtgtaatatt tgctttatta
    14761 ccagaacctt tctggataat catcgcagta ttaccataag caccttgcga aatactggca
    14821 tcgttggcac tgcccgcctg atcaatatat gcaaggttat aatctcctgt ctggtcaatc
    14881 tttgcccggt tgctactacc ttcttgcgca acaaccgcca aaagttttga gcctccctgc
    14941 cgtaactgag cactattatt agtcccagct tgaccaatta tggctgcctg attaaatgaa
    15001 gacttactca attcatttac cgcgaagtta tattctgaat tagctaaatc ataacctgct
    15061 gcggctgcaa tcccaggcgc acccagtatt gttaacatca taaataacaa tttgtttttc
    15121 atgttgtcac cctggacctg gtcgtacatt taagaaatta aatcatttca acttggttgt
    15181 taacgcaacc tgtattttgt taacgctgcg ttacgatgga aagtatgtct gcggaaatat
    15241 ttttaataac tcacccgcgc gttgtatttt tcttttttag ttcataccaa agtattaaaa
    15301 cccacgtaaa tacgctgtta tctacgcaaa aaaatatttt gttttctttt aaatctccgt
    15361 tttccgctat caaaaagcac cagacagtca ttcttcttgc ccgtcgctga ttgctgcgat
    15421 atgtcttgcg cacaagccgt gacaaacctc gtctttttgc agtaaaaaat tgtccacgga
    15481 ggtgtggaga aaaaaca
//
LOCUS       DAPHKZ010000106        15244 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.106, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000106 DAPHKZ010000000
VERSION     DAPHKZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15244
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.106"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..164)
                     /locus_tag="RH288_003457"
     CDS             complement(<1..164)
                     /locus_tag="RH288_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1127 domain-containing protein"
                     /protein_id="HDV4032479.1"
                     /translation="MEFHENRAKAPFIGLVQLWQAVRRWRRQMQTRRVLQQMSDERLK
                     DIGLRREDVE"
     gene            341..1753
                     /locus_tag="RH288_003458"
     CDS             341..1753
                     /locus_tag="RH288_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDV4032480.1"
                     /translation="MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQ
                     QAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDQVLDMLEAHS
                     DSSIVPLSKSTPDVEAPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLML
                     DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIE
                     IPTDPETGISVEALELALEQWPIKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIV
                     IFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLRVGWVAPGRYHDKLM
                     HMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQIYQRNLALYTCWIREYFPCEIC
                     ITRPKGGFLLWIELPEQVDMVCVARQLCRMKIQVAAGSIFSASGKYRNCLRINCALPL
                     SETYREALKQIGEAVYRAME"
     gene            complement(1997..2917)
                     /locus_tag="RH288_003459"
     CDS             complement(1997..2917)
                     /locus_tag="RH288_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012548938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDV4032481.1"
                     /translation="MTNFTTSTPHDALFKTFLTHPDTARDFMEIHLPKDLRELCDLDS
                     LKLESASFVDEKLRALHSDILWSVKTREGDGYIYVVIEHQSREDIHMAFRLMRYSMAV
                     MQRHIEHDKRQPLPLVIPMLFYHGSRSPYPWSLCWLDEFADPTTARKLYNAAFPLVDV
                     TVVPDDEIVQHRRVALLELIQKHIRQRDLMGLIDQLVVLLVTECANDSQITALLNYIL
                     LTGDEARFNEFISELTRRMPQHRERIMTIAERIHNDGYIKGEQRILRLLLQNGADPEW
                     IQKITGLSAEQMQALRQPLPERERYSWLKS"
     gene            3396..4628
                     /gene="mdtM"
                     /locus_tag="RH288_003460"
     CDS             3396..4628
                     /gene="mdtM"
                     /locus_tag="RH288_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HDV4032482.1"
                     /translation="MPRFFTRHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFN
                     ADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMT
                     QFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAAL
                     MHFMHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFL
                     FGAATISLSYIPMMSWVAVSPVILIDAGSLTTSQFAWTQVPVFGAVIVANAIVARFVK
                     DPTEPRFIWRAVPIQLVGLSLLIVGNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFT
                     LFSNKLPKGTVSASLNMVILMVMSVSVEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLA
                     GLLNRVRQHQAAELVEEQ"
     gene            4669..5949
                     /locus_tag="RH288_003461"
     CDS             4669..5949
                     /locus_tag="RH288_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HDV4032483.1"
                     /translation="MNKLIELRRAKRLALSLLLIAAATFVVTLFLPPNFWVSGVKAIA
                     EAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     VALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIDKLKNDP
                     EMAARADAVKSYLKEDEAFNRYLSELWGDLREWLKVDINSEDSRVKERIARAGQWFGE
                     TLIADDALRASLNGHLEQAAHRVAPEFSAFLTRHISDTVKSWDARDMSRQIELNIGKD
                     LQFIRVNGTLVGGCIGLILYLLSQLPALFPLGNF"
     gene            6065..7216
                     /locus_tag="RH288_003462"
     CDS             6065..7216
                     /locus_tag="RH288_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase subunit D"
                     /protein_id="HDV4032484.1"
                     /translation="MSLVTDLPAIFDQFSEARQTGFLTVMDLKERGIPLVGTYCTFMP
                     QEIPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLV
                     VGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEMLRLQKTVEERFGHE
                     ISEDALRDAIALKNRERRALANFYHLGQLNPPALSGSDILKVVYGATFRFDKEALINE
                     LDAMTARVRQQWEEGQRLDPRPRILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGA
                     KATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLKMLSQMVEEYQVDGVVDVILQA
                     CHTYAVESLAIKRHVRQQHNIPYIAIETDYSTSDVGQLSTRVAAFIEML"
     gene            7226..7993
                     /locus_tag="RH288_003463"
     CDS             7226..7993
                     /locus_tag="RH288_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418754.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032485.1"
                     /translation="MAYSIGIDSGSTATKGILLADGVITRRFLVPTPFRPATAITEAW
                     ETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCHGLGARFLAPATRAVIDIGGQDS
                     KVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTSVEQLDSITENVTPHAITSMC
                     TVFAESEAISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQKF
                     ARMLESHLRMPVNTHPDAQFAGAIGAAVIGQRVRTRR"
     gene            7990..8247
                     /locus_tag="RH288_003464"
     CDS             7990..8247
                     /locus_tag="RH288_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDV4032486.1"
                     /translation="MKEFLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLC
                     IWLTCPPGEEIQWVIPGLTESIYCQQDGVWRCIAHYGVSPR"
     gene            8312..9172
                     /locus_tag="RH288_003465"
     CDS             8312..9172
                     /locus_tag="RH288_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418753.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HDV4032487.1"
                     /translation="MTKSISLSKRISVIVILFAIVAVCTFFVQSCARKSNHAASFQNY
                     HATIDGKEIAGITNNISSLTWSAQSNTLFSTINKPAAIVEMTTNGDFIRTIPLDFVKD
                     LETIEYIGDNQFVISDERDYAIYVISLTPNSEVKILKKIKIPLQDSPTNCGFEGLAYS
                     RQDHTFWFFKEKNPIEVYKVNGLLSSNELHISKDEALQRQFTLDDVSGAEFNQQKNTL
                     LVLSHESRALQEVTLVGEVIGEMSLTKGSRGLSHNIKQAEGVAMDASGNIYIVSEPNR
                     FYRFTPQSSH"
     gene            9240..10418
                     /locus_tag="RH288_003466"
     CDS             9240..10418
                     /locus_tag="RH288_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4032488.1"
                     /translation="MPSSTHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAE
                     GSFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWL
                     PPFILVLLIRVLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGIGIALGNEYVLA
                     GLHFDLSSQTLWQGAGALSGMMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAIL
                     YGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPC
                     LTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLL
                     GFVTLIYGIGQILGPALTSMLSNGTSALASATLCGAAALFIAALISTVQLFKLQVVTS
                     "
     gene            complement(10431..10985)
                     /gene="kptA"
                     /locus_tag="RH288_003467"
     CDS             complement(10431..10985)
                     /gene="kptA"
                     /locus_tag="RH288_003467"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HDV4032489.1"
                     /translation="MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLIL
                     CAQKAGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQF
                     LYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKR
                     GLPFWQAENGVWLTSTVAVEFLEW"
     gene            11235..11918
                     /locus_tag="RH288_003468"
     CDS             11235..11918
                     /locus_tag="RH288_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032490.1"
                     /translation="MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWR
                     VFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDG
                     LGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKV
                     IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEER
                     RNPTQGAQA"
     gene            11915..12376
                     /locus_tag="RH288_003469"
     CDS             11915..12376
                     /locus_tag="RH288_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDV4032491.1"
                     /translation="MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTV
                     LLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV"
     gene            12389..13561
                     /gene="iadA"
                     /locus_tag="RH288_003470"
     CDS             12389..13561
                     /gene="iadA"
                     /locus_tag="RH288_003470"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDV4032492.1"
                     /translation="MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPS
                     DIVPNCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVG
                     LLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
                     VKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPIYDLLEN
                     CDVPISKLLPTHVNRNVPLFEQALEFARKGGTIDITSSIDEPVAPAEGIARAVQAGIP
                     LARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTS
                     SVAGFLNLTGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA"
     gene            13626..14537
                     /gene="hypT"
                     /locus_tag="RH288_003471"
                     /gene_synonym="qseD"
     CDS             13626..14537
                     /gene="hypT"
                     /locus_tag="RH288_003471"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HDV4032493.1"
                     /translation="MDDCGAILHNIETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSR
                     RIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRK
                     IKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLL
                     EAPFDHIRLFESQLFPVCASDEHGEALFNLAQPHFPLLNYSRNSYMGRLINRTLTRHS
                     ELSFSTFFVSSMSELLKQVALDGCGIAWLPEYAIQQEIRSGKLVVLNRDELVIPIQAY
                     AYRMNTRMNPVAERFWRELRELEIVLS"
     gene            complement(14530..14922)
                     /gene="iraD"
                     /locus_tag="RH288_003472"
     CDS             complement(14530..14922)
                     /gene="iraD"
                     /locus_tag="RH288_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418746.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HDV4032494.1"
                     /translation="MMRQSLQAVLPEISGNKTSSLRKSVCSDLLTLFNSPHSALPSLL
                     VSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIM
                     LYHDDEPLTFDLVWDNGGWRSATLENVS"
     gene            complement(14919..15002)
                     /gene="idlP"
                     /locus_tag="RH288_003473"
     CDS             complement(14919..15002)
                     /gene="idlP"
                     /locus_tag="RH288_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iraD leader peptide IdlP"
                     /protein_id="HDV4032495.1"
                     /translation="MENEHQYSGARCSGQAAYVAKRQECAK"
BASE COUNT         3439 a         3905 c         3926 g         3974 t
ORIGIN      
        1 cactccacat cctccctgcg taacccgata tccttcaacc gctcatcact catctgctgt
       61 aacacgcgtc gggtctgcat ttgccgccgc caacgcctca ccgcctgcca gagttgcacc
      121 aggccgataa acggcgcttt agctctgttt tcgtgaaatt ccatctgcta cctcctcatc
      181 tttcagagtc ttcatcatcc accttctggc agttcacaat acagattcaa atattacttt
      241 tatttaacat acagacaggt taaaacagca tctgcatccg gttttttagc ctcatctgta
      301 ccggtttttc tctctgtatg gtccacataa ggaatacagc atgacgcgtt atcaacatct
      361 ggcgactctg cttgccgaac ggattgagca agggctgtat cgtcacgggg agaaattgcc
      421 gtcggtgcgc agcttaagtc aggagcacgg cgtcagtatc agcaccgtgc agcaggcgta
      481 tcagacgctg gagacgatga agctcatcac tccgcagccg cgttcgggtt attttgtcgc
      541 acaacgtaaa gcccagccgc cagtaccgcc gatgacgcgt ccggtgcagc gcccggtgga
      601 aattacccag tgggatcagg tgctggatat gctggaggcg catagcgaca gttccattgt
      661 tccgttaagc aaaagcacac cggatgtcga agcgcccagc ctgaaaccgc tttggcggga
      721 gctaagccgg gtggtgcagc ataatctgca aaccgttctc ggttatgact tgttagccgg
      781 tcagcgagta ttgcgagagc agattgcccg cctgatgctc gacagcggct cggtggtcac
      841 cgccgatgac atcatcatca ccagcggctg ccataactcg atgtcgctgg cgttaatggc
      901 agtgtgtaaa ccgggcgata ttgtcgcggt cgaatccccc tgttattacg gttcgatgca
      961 gatgctgcgc ggcatgggcg tgaaagtgat tgaaatccca accgatccag aaactggcat
     1021 cagcgttgaa gcgctggaac tggcgctgga acagtggccg attaaaggca tcattctggt
     1081 gccaaactgt aataatccgc tgggatttat tatgccggac gcgcgcaaac gggccgttct
     1141 ctctctcgct cagcgtcatg atattgtgat ttttgaagat gatgtctatg gcgaactggc
     1201 gacggagtat ccgcgcccgc ggaccattca ttcctgggat atcgacgggc gagtgctgtt
     1261 gtgcagctcg ttcagtaaaa gtattgcacc aggcctgcgc gtgggttggg tcgcaccggg
     1321 gcgttatcac gataaactga tgcatatgaa atacgccatc agcagcttta atgtgccgtc
     1381 cacgcaaatg gcggcggcaa cgtttgtgct ggaaggtcac tatcatcgcc atatccggcg
     1441 gatgcggcag atctatcagc gcaatttggc gctttatacc tgctggatac gggaatattt
     1501 tccctgcgaa atctgtatta cgcgcccgaa aggcggattt ttactgtgga tagaattgcc
     1561 tgaacaggtc gatatggtct gcgtcgcgcg gcagctgtgc cgcatgaaaa tccaggtggc
     1621 ggcaggctcg attttctcag cttccggcaa ataccgtaat tgtctgcgca tcaactgcgc
     1681 tttgccgctc agcgaaacct atcgcgaagc actgaagcaa attggcgagg ccgtgtatcg
     1741 ggcaatggaa taaattcgaa atagcggcga agcgcctgat ttcctctcat gcataacctg
     1801 tgactcgttt tatctttgct gggtcatcgc cacgttccag cctgaattaa gcaaagtacg
     1861 ctttgttcat gccggatgcc atgtgaacgc ctgaccaggt ctacaaaaat ctttaaagtt
     1921 caatatattt aatgggttat gtagacctga taagcatagc gcatcaggct gctttgcgtt
     1981 tgtcatccgt ctctgattag ctcttgagcc atgaatagcg ctcacgctca ggcaagggct
     2041 gccttaatgc ctgcatttgc tctgccgaaa gtccggtaat cttttgtatc cattcaggat
     2101 ccgccccatt ctgcaacaac aatcgaagaa tgcgctgctc cccttttata tatccatcat
     2161 tatgaattcg ctctgcaatc gtcattattc gctccctgtg ttgtggcatt cgacgggtaa
     2221 gttcactgat aaactcatta aaacgcgctt catcgccagt cagtaaaatg taatttaaca
     2281 gcgcagttat ctggctgtca ttagcacact ctgtaaccag taatactacc agttgatcga
     2341 taagccccat cagatcgcgc tggcgaatat gcttttggat caactccaac agggcgactc
     2401 tgcgatgctg cacaatctcg tcgtctggca cgacagtaac atccaccagc gggaacgcgg
     2461 cgttataaag cttccgtgcg gtagtcgggt cggcaaattc gtccagccag cacagggacc
     2521 aggggtaagg actacggcta ccgtgataaa atagcatcgg gatgaccaac ggtagcggct
     2581 ggcgtttatc atgctctata tggcgctgca tcaccgccat ggaatagcgc atcaggcgaa
     2641 aggccatatg aatgtcctcg cggctctgat gttcaatcac cacatagata tagccatcgc
     2701 cttcgcgggt ctttaccgac cataaaatat cggagtgtag cgcccgcaat ttttcatcga
     2761 caaagctggc ggattccagt tttaagctat cgagatcgca cagttcacgt aaatctttag
     2821 gtaagtgaat ctccataaaa tcccgcgcag tgtcagggtg cgtgagaaag gttttaaata
     2881 atgcatcatg cggcgtgctg gtcgtgaagt ttgtcatggc gatccatcac ctgttgaaaa
     2941 agatggcctg actttagcga ctaacaaaac cattctcacc cggcaatttc ccattccccg
     3001 aggcgctttc caggctattt ttattcttct gcaaacgata catttttccg gaaacaagct
     3061 cgcgttttac atgtcctgta cccggcagat attccccttt ccaccgcgct cttttgatta
     3121 accgcaaatt ttaattacac ttaaggtgta tattttctat gcaacccatc aattcaagag
     3181 gtgtaatgtg ctgatgacta tttgtaatcg ttatacattc tgacccgaag tcagaaagta
     3241 tttctctgtc tgtgtgttca caggcagtgt ggttgattac atgaaattca gtacatttgc
     3301 agtctcgttg cccttctcac ctgcctttcg tcattaccga cggtattgaa tttcgttttc
     3361 cccgttgggg ttctccggac aaggagttgt ttgttatgcc acgttttttt acccgccatg
     3421 ccgccacgct gtttttcccg atggcgttga ttttgtatga ctttgctgcg tatctgtcga
     3481 cggatctgat ccagcctggg atcattaatg tggtacgtga ttttaatgcc gatgtcagtc
     3541 tggcccctgc tgccgtcagt ctctatcttg ctggcggtat ggcgttacag tggctgctgg
     3601 ggccgctttc cgacagaatt ggccgcaggc cggtgctgat taccggggcg ctaattttta
     3661 cccttgcctg cgccgcgaca atgttcacaa cgtctatgac acagtttctt atcgcgcgtg
     3721 caattcaggg caccagtatc tgttttattg ccaccgttgg ttatgtcacg gtgcaggagg
     3781 cgttcggaca gacaaaaggg atcaagttga tggcgattat cacctccatc gtactgattg
     3841 cgccgattat cggcccgctt tccggcgcag ctctgatgca ctttatgcac tggaaagtcc
     3901 tttttgccat cattgcggtt atgggtttta tctcatttgt tggcttactg ttggcgatgc
     3961 cagagacggt gaagcgcggc gcggttccgt ttagcgccaa aagcgtcttg cgcgattttc
     4021 gtaatgtctt ttgcaatcgg ctgttcctct ttggcgcagc aaccatctct ttaagctata
     4081 tcccgatgat gagctgggtg gctgtctcgc cggtgatcct tatcgatgca ggcagcttaa
     4141 caacttcgca gttcgcctgg acacaggttc cggtgttcgg cgcggtgatt gttgcgaatg
     4201 ccatcgtggc gcgttttgtt aaagatccga ccgaaccgcg gtttatctgg cgtgccgtac
     4261 ccattcaact ggtcggcctc tcgctgttga ttgtcggcaa tctgctgtcg ccgcacgtct
     4321 ggctgtggtc ggtgctgggc accagtctgt atgctttcgg gattggtttg attttcccga
     4381 ccttattccg ctttacgctg ttttccaata agttaccgaa agggaccgtc tccgcatcgc
     4441 taaatatggt gatcctgatg gtgatgtcgg tctcggtcga aatcggccgc tggctatggt
     4501 ttaacggcgg tcgcttgccg tttcatctgt tagccgttgt ggcgggcgtt atcgtcgttt
     4561 tcaccctggc gggattgctc aatcgcgtgc gccagcatca ggcagccgag ctagtggagg
     4621 agcagtgatt tttgcgcgat cctgccgtca ggctctattc ttaacgttat gaataaactc
     4681 atcgaactca gacgcgccaa aaggttggcg ctctctttac tgcttatcgc cgctgctacc
     4741 tttgtcgtta cgctgttttt gccgcccaat ttttgggtga gcggcgtgaa ggcgattgct
     4801 gaagcggcga tggtcggcgc gctggcggac tggtttgcgg tggtggcgct gtttcgccgc
     4861 gtgccgattc cgatcatttc tcgccatacg gcgattatcc cgcgtaataa agaccggatt
     4921 ggcgaaaatc tcggccagtt cgtgcaggaa aaatttcttg atactcaatc cctggtggca
     4981 ttgattcgac gccacgaacc ggcgttgctg attggcaact ggtttagcca gccagaaaac
     5041 gcccgccgcg ttggtcagca tctgttgcag atcatgagcg gttttctcga acttaccgat
     5101 gatgcgcgta ttcagcgcct gcttaagcgc gcggtccatc gggcgattga taaggtcgat
     5161 ctttccggca ccagtgcgtt gatgctggag agtatgacca aaaacgatcg tcatcaggtg
     5221 ctgctggata cgctgatcgc acagttgatc gcccttctcc agcgcgataa atcgcgcaag
     5281 tttatcgccc agcaaattgt tcgctggctg gagagcgagc atccactgaa agccaaaatt
     5341 ctccccaccg aatggttggg cgaacatagc gcggagttgg tttctgacgc ggtgaattct
     5401 ttgcttgatg atattagtcg cgatcgtgcg catcagatcc gccatgcgtt tgatcgcgcc
     5461 accttcgccc tgatcgacaa gctgaaaaac gatccggaaa tggcagcgcg agccgatgcc
     5521 gtaaaaagct atctgaaaga agatgaagct tttaatcgct atctcagtga attgtggggg
     5581 gatttacggg aatggctgaa agtggatatc aacagtgaag attctcgtgt gaaagaacgc
     5641 atcgcacgag cgggtcaatg gtttggcgaa acgttaattg ccgatgatgc cttgcgggcg
     5701 tcgttaaatg gtcatcttga acaagccgcg caccgcgtcg cgcctgagtt ttccgcattc
     5761 ctgacgcgcc acatcagcga tacggtaaaa agctgggatg cgcgggatat gtcgcggcaa
     5821 atagagttaa atatcggcaa agatctgcag tttattcgtg tcaacggtac gctggttggc
     5881 ggttgtattg ggctaatttt atatttgctg tcgcagctcc cggccttgtt ccccctcggc
     5941 aatttttaga aatccatgaa aaactaagtg gctaaccgcg agagagatca aataaaccat
     6001 actaaaagaa tggtaataat gtggcctctt ttcattatct cccgtggtac ggggaaggaa
     6061 aatcatgtca cttgtcaccg atctacccgc cattttcgat cagttctctg aagctcgcca
     6121 gacaggcttt ctcaccgtca tggatctcaa ggagcgcggc attccgctgg ttggcactta
     6181 ctgcaccttt atgccgcaag agatcccgat ggcagccggt gcggttgtgg tttcgctctg
     6241 ttccacctct gatgaaacca ttgaagaagc ggagaaagat ctgccgcgca acctctgccc
     6301 gctgattaaa agcagctacg gcttcggcaa aaccgataaa tgcccctact tctacttttc
     6361 ggatctggtg gtcggtgaaa ccacctgcga cggcaaaaag aaaatgtatg aatacatggc
     6421 ggagtttaag cctgttcatg tgatgcaatt gcccaacagc gttaaggacg atgcctcgcg
     6481 tgcgttatgg aaagccgaga tgctgcgctt gcaaaaaacg gtagaagaac gttttgggca
     6541 cgagattagc gaagatgctc tgcgcgatgc cattgcgctg aaaaaccgcg aacgtcgcgc
     6601 actggctaat ttttatcatc ttgggcagtt aaatcctccg gcgcttagcg gcagcgacat
     6661 tctgaaagtg gtttacggcg caaccttccg gttcgataaa gaggcgttga tcaatgaact
     6721 ggatgcaatg accgcccgcg ttcgtcagca gtgggaagaa ggccagcgac tggacccgcg
     6781 tccgcgcatt ttaatcaccg gctgcccgat tggcggcgca gcagaaaaag tggtgcgcgc
     6841 gattgaagag aatggcggct gggttgtcgg ttatgaaaac tgcaccgggg cgaaagcgac
     6901 cgagcaatgc gtggcagaaa cgggcgatgt ctacgacgcg ctggcggata aatatctggc
     6961 gattggctgc tcctgtgttt cgccgaacga tcagcgcctg aaaatgctca gccagatggt
     7021 ggaggaatat caggtcgatg gcgtagttga tgtgattttg caggcgtgcc atacctacgc
     7081 ggtggaatcg ctggcgatta aacgtcatgt gcgccagcag cacaacattc cttatatcgc
     7141 tattgaaaca gactactcca cctcggatgt cgggcagctc agtacccgtg tcgcggcctt
     7201 tattgagatg ctgtaaggag tggcagtggc atattcgatt ggcattgatt ccggctcaac
     7261 cgccaccaaa gggatcttac tggcagacgg cgtgattacg cgccgtttcc tcgttccaac
     7321 cccctttcgc ccggcaacag caattactga agcctgggaa actctgcgcg aagggttaga
     7381 gacaacgccg tttctgacgc tcaccggcta cgggcggcaa ctggtggatt ttgccgataa
     7441 acaggtaacg gaaatctcct gtcacgggct gggcgcacgg tttcttgcgc cagcaacgcg
     7501 cgcggtaatc gacatcggtg gtcaggacag caaagtgatt cagcttgatg atgacggtaa
     7561 cctgtgcgat ttcctgatga atgacaaatg cgcggcgggc accgggcgtt tcctggaggt
     7621 gatctcgcgc acgcttggca ccagcgtcga gcaactcgac agcattaccg aaaatgtcac
     7681 gccgcacgcc atcacgagta tgtgcacagt gtttgctgaa tcagaagcga tcagcctgcg
     7741 ctcagcgggc gtcgcgccag aagcgattct cgccggagtg attaacgcga tggcgcggag
     7801 gagtgccaat ttcattgctc gtctctcctg tgaagcgccg attctgttta ctggtggcgt
     7861 tagtcattgc cagaagtttg cccggatgct ggaatctcac ctgcgaatgc cggtaaatac
     7921 ccatcctgat gcgcaatttg ctggcgcaat tggcgcggcg gtaattggtc aacgagtgag
     7981 gacacgccga tgaaagagtt tttattttta tttcactcca cggtcggcgt catacaaacc
     8041 cgcaaagcgt tgcaggcagc gggcatgact tttcgcgtca gcgatattcc ccgtgattta
     8101 cgcggcggct gcgggttatg catttggctg acctgtcccc ccggcgagga aatacaatgg
     8161 gtgatccctg ggctgactga gtcaatttat tgccagcagg atggtgtctg gcgctgcatt
     8221 gcacattacg gggtttctcc gcgttaagga ttcattaagg tcgctacgta tacttctcga
     8281 tatcttattg atttgcctta aagggattac cgtgacaaaa agtatttcgt taagtaaacg
     8341 catctccgtt attgtgattc tttttgccat tgtggcagtg tgtactttct tcgtgcaatc
     8401 ttgcgcccgt aaaagcaatc atgcagcatc atttcagaat taccacgcca ccattgacgg
     8461 caaagaaatt gcaggcataa cgaataatat ctcttcgctg acctggtcgg cacaaagcaa
     8521 tactcttttt agcactatca acaaacctgc cgccattgtt gaaatgacca ccaatggtga
     8581 ttttatccgc acaattcctc tggattttgt taaggatctc gagacgatcg aatacattgg
     8641 cgataatcag tttgtcatta gcgatgagcg cgattacgcc atttatgtga tttcactgac
     8701 cccaaactcg gaagtaaaaa tcctcaaaaa aataaaaatc ccgctgcaag actccccaac
     8761 caattgcggt tttgaagggt tggcttattc tcgccaggat cacactttct ggttttttaa
     8821 agagaaaaat ccgattgagg tctacaaagt taacgggctg ttaagtagca atgaattaca
     8881 catcagcaaa gacgaggcac tacaacggca atttacttta gatgatgtgt ccggcgcaga
     8941 atttaaccag caaaaaaata cgcttctggt gctgtctcat gaatctcgcg cactccagga
     9001 agtaaccctg gttggcgagg ttatcggtga aatgtcacta accaaaggca gtcgaggttt
     9061 gtcgcataac atcaaacagg ccgaaggggt tgcgatggat gcctctggta atatttatat
     9121 cgttagcgaa ccaaatcgtt tttatcgctt tacccctcaa tcatcgcatt aacaggctgg
     9181 catgcttcac ctttttgtta ttaacttgtt aacaacaaaa atgacaaaca aggttaaaca
     9241 tgccttcgtc cacgcatccc gtagaacgct tttctttcag caccgcgctt ttcgggatgc
     9301 tggttctgac cttaggtatg ggtttaggcc gcttccttta tacgcctatg ttgcccgtca
     9361 tgatggcgga aggatcgttt tcatttagcc agctctcgtg gattgccagc ggcaactatg
     9421 cggggtatct ggctggcagt ctgctatttt cttttggcgc atttcaccag ccatcgcgcc
     9481 tgcgcccatt tctgttggct tctgccctgg cgagcgggtt gttgatcctc gcaatggcat
     9541 ggttgccgcc atttattctg gtgttattga ttcgcgtcct ggcgggtgtc gccagcgccg
     9601 gtatgctgat ttttggttcg acgctgatta tgcagcacac gcgccatcct tttgtgctgg
     9661 cagctttgtt ttctggcgtt ggcattggca tcgcactggg caatgaatat gttctggcag
     9721 gcctgcattt tgacctctcc tcgcaaacgt tatggcaagg cgccggggcg ctttctggca
     9781 tgatgctgat tgcacttacg cttttaatgc cctcgaaaaa acacgccatc acaccaatgc
     9841 cattggcaaa aacggagcaa cagataatga gctggtggtt actggctatt ctgtacggcc
     9901 tggcgggatt tggttatatc atcgtcgcga cttacctgcc gctcatggcg aaagatgcag
     9961 gctcaccatt gttaaccgcc catctctgga cgttagtcgg cttatcaatt gtgcctggtt
    10021 gctttggctg gctatgggca gcaaaacgtt ggggggcttt gccctgcctg acggcgaatt
    10081 tgctggtgca ggctatctgt gtgctgctta ctctcgccag cgactcgcct ctcttgctta
    10141 tcatcagcag tcttggtttt ggcggtacct ttatgggcac gacatctctg gtgatgacta
    10201 tcgcccgcca actgagcgta ccgggaaatc tcaatctttt aggctttgtg acgctcattt
    10261 acggcattgg gcaaatcctc ggcccggcgc tgaccagtat gctcagcaat ggaacatcgg
    10321 cgcttgccag cgccactctc tgcggcgcgg cggcgttgtt tattgctgcg cttatcagca
    10381 cagtgcaatt atttaagcta caagtggtca cttcatgagg gaagtttccc ttaccactca
    10441 agaaactcaa ccgcaaccgt tgatgtcagc cagaccccgt tttccgcttg ccagaaaggg
    10501 aggcctcgtt tcgccatttc ctgtgctttg acggttaaaa taaccggcga tccgtgtctt
    10561 gctcccactt tgcgtgccgt tgcttcatca gcagagagat gtacgtagtg acgctcacct
    10621 gcaatcagcc cctgtttttt tatctcgtca aggaaacggc ttgccgtacc gtggtagaga
    10681 aactgtggcg gtgttttttc ggcaaaggaa atagcgacct gcgaagtcga atgcccctga
    10741 accgcgcgga tgcacctacc atcactggaa taactaaaac gctttttatc gctggtggca
    10801 accacagtat ccagcaatgc acgggttaac cgcttgcccg ctttttgggc acaaagtatg
    10861 agcttatcga tatccgccca tccttcacgg tccagtacga taccaatcgc ctccggtttg
    10921 tgtcggagga caaaacttaa aaacttgctc gtatccgcca gctctttttc gttgtacttt
    10981 gccatctcgt tttcgtccct ggattttctg tttttattta ctgatgtcat tgtcacttgg
    11041 tttatgaatt ttctgcaact caatcctgcg cagagccttt tccacacagc gtaatttttc
    11101 cgctatgcaa aaaacgcata gccagaaaca tacttgcatt ttccccatac ccacatggct
    11161 gataaggttt ttcagttcca ggaattttcc tggctcaagc aacacacaaa cacaaaaaaa
    11221 caatggggat tgttatgaca caacaagggg atgctgtagc cggggagctg gcgacagaaa
    11281 aagtgggcat taaagggtat ctggcctttt ttctcaccat aatctttttt tccggtgttt
    11341 tttccggaac agacagctgg tggcgcgttt ttgatttttc cgttctgaac ggatcgtttg
    11401 ggcaactgcc tggtgcgaac ggagccacca cctcatttcg cggcgcgggt ggcgcggggg
    11461 ctaaagatgg ctttctcttt gcgctggagc tggcaccgtc agtcattctc tctctgggga
    11521 ttatttcaat taccgatggt cttggtggat tacgcgccgc gcagcagtta atgacacctg
    11581 tgctaaaacc gttgttgggc attccaggga tctgctcgct ggcgctgatc gctaacctgc
    11641 aaaacaccga tgccgccgcc ggtatgacca aagagctggc gcaggaaggt gaaattaccg
    11701 aacgcgataa agtgattttc gccgcatatc aaaccagcgg tagcgccatc atcaccaact
    11761 acttctcttc cggcgtcgcg gtgtttgcct ttctgggcac gtccgtaatc gtacctttag
    11821 ccgtcatcct ggtgtttaaa tttgtcggag ccaacatttt gcgcgtctgg cttaacttcg
    11881 aagaacgtcg caacccaacg caaggagcgc aagcatgaca actcaggtcc gcaaaaacgt
    11941 catggatatg tttatcgatg gcgcgcgccg tggctttact atcgccacga ccaacctgct
    12001 gccaaacgtg gtgatggcgt ttgtcatcat tcaggcgctg aaaattaccg gcctgctcga
    12061 ctgggtgggg catatctgtg aacccgtaat ggcgctgtgg ggattacccg gtgaagcggc
    12121 aaccgtcctt ttagccgcat taatgagtat gggtggcgca gtcggtgttg ccgccagtct
    12181 ggcaaccgct ggcgcattaa ccggtcacga tgtcaccgtt ttactgcccg cgatgtattt
    12241 aatgggcaac ccggtgcaaa atgtcggtcg ctgcctgggg acagccgaag tgaatgccaa
    12301 atattacccg catatcatta cggtctgcgt gattaacgca ttgctgtcga tctgggttat
    12361 gcagcttatt gtttaacaag gagttaccat gattgattat accgcagccg gttttaccct
    12421 gctgcaggga gcgcatttgt atgcgccgga agatcgggga atttgcgatg tcctcgtcgc
    12481 taacggcaaa attatcgccg ttgccagcaa tatcccttct gacattgtac cgaactgcac
    12541 ggttgtcgat ctcagtgggc agatcctctg cccaggtttt attgatcaac acgtccattt
    12601 gattggcggt ggcggcgaag caggtcccac gacgcgcacg ccggaagtgg cgctaagtcg
    12661 cctgacggaa gcgggcgtca cgtcagtggt tggtctgctg ggcaccgact ctatctctcg
    12721 ccacccggaa tccctgctcg ccaagacccg tgcgctcaat gaagaaggca tcagcgcctg
    12781 gatgctgacc ggcgcttatc atgtcccttc ccgcaccatt acgggttccg tggaaaaaga
    12841 cgtggcgatt atcgatcgtg tgattggcgt gaaatgcgcc atctctgatc accgttctgc
    12901 cgcaccggac gtttatcacc tggccaatat ggcggcagaa tcccgcgttg gcggtttgct
    12961 cggcggtaaa cctggcgtca ccgtgttcca catgggcgac agtaaaaagg cgttacagcc
    13021 tatttatgac ctgctggaaa actgcgatgt gccgatcagc aagctgctgc cgacccacgt
    13081 taaccgcaac gtaccgttgt ttgagcaggc gctggagttc gcgcgcaaag gcggcaccat
    13141 cgatatcacc agcagcattg acgaaccggt cgcccctgcc gaaggtattg cccgcgccgt
    13201 tcaggcgggt attccgctgg cacgcgtcac cctcagctcc gacggcaacg gtagccagcc
    13261 gttcttcgat gacgaaggga atttaaccca tatcggtgtt gccggttttg aaacgttgct
    13321 ggaaaccgtg caggtgctgg tcaaagacta tgatttcagt atcagcgatg ccctgcgccc
    13381 gctcaccagt agcgtagccg gtttccttaa cctgaccggg aaaggcgaaa ttctgccagg
    13441 caatgatgct gacttgctgg tcatgacgcc agaactgcgc attgagcagg tatacgctcg
    13501 cggcaaactg atggtcaaag acggcaaagc ctgcgtgaaa ggaacgtttg aaacggctta
    13561 aacggttgtc agccgcccga atggacgtag aatgcccgca agggcggctg acagagtaaa
    13621 acgtaatgga tgactgtggt gcgattttgc ataatattga aaccaaatgg ctttatgatt
    13681 ttctgaccct ggaaaaatgc cgcaattttt cccaggcggc agtcagtcgc aacgtctcgc
    13741 aaccggcatt cagccgccgc atccgtgcgc tggaacaggc gattggtgtt gaattgttta
    13801 accgccaggt aacgccgctg caactctcag aacaagggaa aatcttccat tcgcagatcc
    13861 gccatctgtt gcaacagtta gagagcaatc tggcagagct gcgtggcggc agcgattacg
    13921 cgcaacgaaa aatcaagata gccgctgcac actctctttc cctcgggctg ttaccgtcca
    13981 ttatcagcca gatgccgccg ctctttacct gggcaattga agctattgat gtcgatgaag
    14041 cggtcgataa actgcgtgaa gggcaaagtg actgtatttt ttcctttcac gacgaagatt
    14101 tgctggaagc gccgtttgac cacattcgct tatttgaatc tcaattgttc cctgtctgcg
    14161 ccagtgacga acacggagaa gcacttttta acctcgcgca gccacacttt ccgttactga
    14221 attacagccg caactcctac atggggcgat tgattaatcg caccctgacg cgccacagtg
    14281 agttaagttt cagcaccttt tttgtctctt cgatgagcga gcttttaaag caggttgccc
    14341 tcgacggctg tgggattgcc tggctgccgg agtacgccat ccaacaagaa attcgcagcg
    14401 ggaagctcgt tgtactgaat cgggacgaac tggtgatccc gattcaggcc tatgcatacc
    14461 ggatgaatac ccgcatgaat cccgttgccg aacgcttctg gcgtgaactg cgcgagctgg
    14521 agattgtgct tagctgacat tctccagcgt cgcactgcgc caaccgccat tatcccagac
    14581 cagatcaaac gttagcggtt catcgtcgtg gtacagcatt atctcaaggc tgatcgccag
    14641 agtgtggcag tacgcttctt tcaaattaac ctgcaacgcc gcaatccgtg gctcatgaaa
    14701 taacagtgca gaacgcagct gacggcaata ccagctctgg agatgtttgt cgctcgggtt
    14761 atgcacttgc cactcgggca tgcctgaaac aagtaatgac ggtaatgccg aatgaggaga
    14821 attaaaaaga gtgaggagat cgctgcatac cgatttacgc agcgatgacg ttttattgcc
    14881 tgaaatttca ggtaaaacag cctgaagtga ttgtcgcatc attttgcgca ctcctgacgt
    14941 ttagcaacat atgcggcttg ccctgaacac cgggcaccac tgtattgatg ctcattttcc
    15001 atagccattc ccttttgttc attacatcca tgtcagtctg agacaggcct gaatcctgtc
    15061 agcaaagtat aaaaccttac ttgcctatga atatctactg acttttcagg aaaaaagtca
    15121 tgatttgata aaaatcatca aactcaaaaa aaaaccgcta gtatattctg aatattccga
    15181 atagttacgt agatgaaaat acttgtcacc gctgctactt aattccggtg ggaaattatt
    15241 tatt
//
LOCUS       DAPHKZ010000107        15066 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.107, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000107 DAPHKZ010000000
VERSION     DAPHKZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15066
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.107"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(399..1319)
                     /gene="malM"
                     /locus_tag="RH288_003474"
     CDS             complement(399..1319)
                     /gene="malM"
                     /locus_tag="RH288_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HDV4032496.1"
                     /translation="MKMNKSLIALCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSA
                     ALQQLTWTPVDQSKTQTTQLATGGQQLNVPGISGPVAAYSVPANIGELTLTLTSEVNK
                     QTSVFAPNVVILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTQLLDPAKAYAKGVGNSIPDIPDPVARHTTDGLLKLKVKTNSSSSVL
                     VGPLFGSSAPAPVTVGNTAAPAVAAPAPAPVKKSEPMLNDTESYFNTAIKNAVAKGDV
                     DKALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            complement(1562..2902)
                     /gene="lamB"
                     /locus_tag="RH288_003475"
     CDS             complement(1562..2902)
                     /gene="lamB"
                     /locus_tag="RH288_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /protein_id="HDV4032497.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEAT
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
                     FGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDY
                     GRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSG
                     VAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVG
                     IRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFA
                     TYAKWDEKWGYDYNGDSKVNPNYGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW"
     gene            complement(2974..4089)
                     /gene="malK"
                     /locus_tag="RH288_003476"
     CDS             complement(2974..4089)
                     /gene="malK"
                     /locus_tag="RH288_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HDV4032498.1"
                     /translation="MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQ
                     VGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDV
                     VLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV"
     gene            4454..5644
                     /gene="malE"
                     /locus_tag="RH288_003477"
     CDS             4454..5644
                     /gene="malE"
                     /locus_tag="RH288_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HDV4032499.1"
                     /translation="MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
                     LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGL
                     TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
                     KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYE
                     EELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQT
                     RITK"
     gene            5798..7342
                     /gene="malF"
                     /locus_tag="RH288_003478"
     CDS             5798..7342
                     /gene="malF"
                     /locus_tag="RH288_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HDV4032500.1"
                     /translation="MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAI
                     TTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
                     ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGT
                     LTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKP
                     FLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            7357..8247
                     /gene="malG"
                     /locus_tag="RH288_003479"
     CDS             7357..8247
                     /gene="malG"
                     /locus_tag="RH288_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HDV4032501.1"
                     /translation="MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNF
                     ATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITI
                     VFLLAQRWLVNGLTAGGVKG"
     gene            8619..10094
                     /gene="xylE"
                     /locus_tag="RH288_003480"
     CDS             8619..10094
                     /gene="xylE"
                     /locus_tag="RH288_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose transporter XylE"
                     /protein_id="HDV4032502.1"
                     /translation="MNTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVA
                     PQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGS
                     AWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIR
                     GKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLY
                     TVPESPRWLMSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVG
                     VIVIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIM
                     TVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCW
                     VLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGC
                     MGVLAALFMWKFVPETKGKTLEELEALWEPETKKTQQTATL"
     gene            complement(10138..10548)
                     /gene="psiE"
                     /locus_tag="RH288_003481"
     CDS             complement(10138..10548)
                     /gene="psiE"
                     /locus_tag="RH288_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HDV4032503.1"
                     /translation="MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLAD
                     VLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLII
                     VDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE"
     gene            complement(10674..10817)
                     /locus_tag="RH288_003482"
     CDS             complement(10674..10817)
                     /locus_tag="RH288_003482"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032504.1"
                     /translation="MFQRNIVDFSRIAGGWESPEWVIFELPALVRFVLPDAPPGAAYP
                     AYG"
     gene            10818..11096
                     /locus_tag="RH288_003483"
     CDS             10818..11096
                     /locus_tag="RH288_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032505.1"
                     /translation="MKRNLIKVVKMKPYFAALMLSVSVLPAYAGPLGTADKADLPQSN
                     VSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH"
     gene            complement(11143..13239)
                     /locus_tag="RH288_003484"
     CDS             complement(11143..13239)
                     /locus_tag="RH288_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HDV4032506.1"
                     /translation="MKKRHLLSLLALGISMACYGETYPAPIGPSQSDFGGVGLLQTPT
                     ARMAREGELSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTRQYSSVEAFSGDQTY
                     KDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGY
                     LGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYRVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPSYNDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADPQIQAKGDTLYVTGE
                     QVKYRDSREGIIRANRIVMNDLPDGIKTIRITENRLNMPQATTETDVASLKNHLAGEP
                     LGHETTLAQKRVEPVVPQSTEQGWYIDKSRFDFHIDPVLNQSVGGPENFYMYQLGVMG
                     TADLWLTDHLLTTGSLFANLANNYDKFNYTNPPQDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQHLGNGFYGQVYGGYLETMFGGAGAEVLYRPLDSNWAFGLDANYVKQRDWRSA
                     KDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITNVSKEEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFQLYDMTSDRSVNFR"
     gene            complement(13239..13976)
                     /locus_tag="RH288_003485"
     CDS             complement(13239..13976)
                     /locus_tag="RH288_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HDV4032507.1"
                     /translation="MIKQTIVALLLSVGASSVFAAGTVKVFSNGSSEAKTLTGAEHLI
                     DLVGQPRLANSWWPGAVISEELATAAALRQQQALLTRLAEQGADSSADDAAAINALRQ
                     QIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWVGPPPSTVTLFGLISRPGKQP
                     FTPGRDVASYLSDQSLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVG
                     LADSVWSETPDALNADILQTLTQRIPQ"
     gene            complement(13973..14611)
                     /locus_tag="RH288_003486"
     CDS             complement(13973..14611)
                     /locus_tag="RH288_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418451.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HDV4032508.1"
                     /translation="MKRPALILICLLLQACSATTKELGNSLWDSLFGPPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQDQATLVTQHGRLVKTLLGGDNLI
                     EVNNLAADPLIKPAQIVDGASWTRTMGWTEYQQVRYATARSVFKWDGTDTVKVGSDET
                     PVRVLDEEVSTDQARWHNRYWIDSEGQIRQSEQYLGADYFPVKTTLIKAAKQ"
     gene            complement(14725..14967)
                     /locus_tag="RH288_003487"
     CDS             complement(14725..14967)
                     /locus_tag="RH288_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032509.1"
                     /translation="MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
BASE COUNT         3502 a         3969 c         3873 g         3722 t
ORIGIN      
        1 tgttttatat ttaaaaaaat attgctgata taaataaagt tttctcgatt taaccctggc
       61 accccattaa aattacgtag taaatcaaga tcgactatat tatttccttg caccacacca
      121 tgttttatca aagagttatt gccgtcaaac tttgagatat gacctaacat aaaacctctg
      181 cattacagaa atgaaataac tggaaaaagt agcctgagcg tccagacact accggcgaaa
      241 ggaaaagaat ctctgataag gcattgagat aatgcacatt cttagtgaag aagaaatgaa
      301 gtactataaa aaatcgctca tatccctgga atgaagcata aaaaaaggtg cgccaggaga
      361 cgcaccagtt gttgcaaaat cagcactgtg gggcgtaatt accccttgcc ttttacactg
      421 ctgataaagg tggaacgggc agatgtcgat cccaggcgtt cagcttcatc aagcagtttt
      481 aacgccttat caacatcacc tttcgcgaca gcgtttttga tcgcggtatt aaaataactt
      541 tccgtgtcgt tgagcatcgg ctcgcttttc ttcaccggtg ccggagcggg tgcagccaca
      601 gctggtgccg ccgtgttgcc taccgtaacc ggagctggag cggaagaacc aaataaaggc
      661 ccgaccaaca cgctggagct ggagttcgtt ttgactttca gtttcagtaa gccatcggtg
      721 gtatgacgag caaccggatc gggaatatcc gggatcgagt taccaacgcc tttggcatag
      781 gctttagccg ggtcgagcag ttgggtcgtc tgctggagat ctttttccgt ggtaaagacc
      841 agaacataaa gtttttgctg ccccaatgcc ggtgtcaggc gcataacgcc ttccagccga
      901 tctgcactca tcacgcctgg ttcctggtag gtgaaataac tgctggggaa gaaggctgat
      961 ggggtcatat tctgatcaag aatcaccacg ttcggcgcaa atacgctggt ttgtttgttc
     1021 acttcgctgg tcagcgtcag ggtcagttcg ccaatgtttg ccgggacgct gtacgcagca
     1081 accggaccac tgatgccggg aacgttcagt tgttggccgc cagtcgccag ttgggtggtc
     1141 tgagttttag attgatcgac cggtgtccag gtgagttgtt gcagcgcggc agatggaatg
     1201 gctggcgcgt cgctggtgtt ttgcggtacg tagttaacat cggcaaggct gattccaggc
     1261 gcgcttgcca gtaaccctgc tgataaacag agggcgatga gacttttatt cattttcatt
     1321 gttttcacct caaaatctgg agctcagcgg tagccaggca atagcgcgct aaacccgata
     1381 atcagagggg ctttcgcccc tttcagataa tgacaacctg tttttatgcc ggatgcggcg
     1441 taaacgcctt atccggccta catttgacag ccgttgtagg cctgataaga cgcgcaagcg
     1501 tcgcatcagg cgttggttgc cgaatgcggc gtaaacgcct tatccggccc aggttttgct
     1561 attaccacca gatttccatc tgggcaccga aggtccactc gtcgctgtcg ccacgaccga
     1621 agctgccgcc gttgaaatca gcaggaacgg ctttgccgta gttcgggtta accttgctat
     1681 cgccgttgta gtcataaccc catttctcat cccacttggc gtaggttgcg aagacacgaa
     1741 tagccgggcg tgaccagatg ctgtcgccag cctgccattg ttgtgcgagg gtaattttgt
     1801 actgattgtt cttgtcgccg gtgcgctggg attcgacgtt gtcgtagccg atttccatca
     1861 cggtgctcat gattggcgtc cacttgtaca tcgggcgaat accaacggtc caccacttgg
     1921 tgccgttgtc gttatcccag ttgatatcct ggtacatacc cacgtacatc atgtcccagt
     1981 tgtcgcccat ggagatcgca ccgtggtcga ggatacgcag catgtgaccg ttgttgttga
     2041 tattgtaggc aaatttttcg ttatcaaacg cgacgccaga accctgcgac agacctttac
     2101 cctgcgaggt catcgagtca gtagcgtact gaacaacaaa cttgttaaag cccttcagga
     2161 cactctgagt atgttcagca gtgaataacc agccgtcttt cgatgcgcca tcaaccagac
     2221 gatagttatc acgcaggttg gcacgaccgt agtcgacacc cagttctaat gtgccgcccg
     2281 ggttgatttc catctgcgct aaacgcacat cgaaaacgtc gttcgcggtt tcgttggtat
     2341 agtcataaat attgttgctg gcaaaagagg aagaaccacc agcttcagag gagcgggttg
     2401 ctgccagaga gagtttaccg aagccaacat cgatgttttc cagaccggca ccaggaccag
     2461 aaatatccca gtagtagaag tcgatcatat gaacgtcatg acgttggtag aagcgcttac
     2521 ctgcccagat ggtggaacct ggcagccatt cgatcaggtt tttaccctgc acgtttgctt
     2581 cacggaaggc cggatcggta gcttcccagt cattctgttg cgcgacggaa taggccacgt
     2641 tagtgtcgaa atagaagctc ttatcgccct ctttccacac ttcctgaccc aattttaatt
     2701 cagcataagt ttcacattcg ttgccaagac ggtatttact ttgagcaccg gtagtctgga
     2761 aacactgttg ttcaccgccg ctacctgtcc agccaatacc ggaacgtgca tagccgtgga
     2821 aatcaacagc cattgcctga gcagacatta cgcccgctgc gacggcaacc gccagaggaa
     2881 gtttgcgcag agtaatcatc attctatctc ctgagtcatt gcttttcttt tttcacatca
     2941 cctgtgacag gctttgtgtg ttttgtgggg tgcttaaacg cccggctcct tatgcagtcg
     3001 acgacatgca gtgccatcct cacggaacag atggcaacgc tctggcggca ggccgatagc
     3061 gaatgtggca ccttcttcta ccaacaccac gtcgttctgg cggtacacca ggttttgacg
     3121 aatggaaggg atctggatat ggatttgggt ttcgttgccg agttgctcga cgacctgaac
     3181 ttcaccctca aggatgacgt cagcgatatc actcggcagt agatgttccg ggcgaatacc
     3241 cagcgacata ttggctccaa cctggacatc acggctttca actggcagcc agacttgctg
     3301 acgatttggc atcggcagct ccacctgcac ttgatcgatt gcagtggcgg tcacttttac
     3361 cggcaggaag ttcatctttg gcgaaccgat aaatccggcg acaaaacggt ctgccggata
     3421 gtggtacagc tccagcggtt tcccaacctg cgccacgcga ccggcgtcca gcaccacgat
     3481 tttgtcggcc agcgtcatcg cttcgacctg atcgtgggtg acgtaaatca ttgtgcggcc
     3541 caggcgttta tgcagacggg agatttcgat acgcatttgc acacgcagtg cagcatcgag
     3601 gttggagagc ggttcatcga gcaaaaatac gcttggctcg gccaccagcg tacggccaat
     3661 cgccacgcgc tgacgctgac caccggagag cgctttcggt ttgcgatcca gcaaatgcgc
     3721 cagttgcagc acttccgcca cctggttgac gcgttggtta atcacctctt tttttgcgcc
     3781 agccagtttc aggccaaatg acatgttttc tgctactgac aggtggggat agagcgcgta
     3841 agactgaaac accataccaa cgccgcgttc tgctggcgga gtgtcattca tccgtttctc
     3901 accgatgaac aggtcgccgc tggtgatcgt ctcaagcccg gcaatcatgc gcagtaaagt
     3961 cgatttaccg cagccagacg gtccgacaaa caccacgaat tcaccttcat ggatatcgag
     4021 attgatatct ttcgatacca cgacctcgcc ccaggctttc gttacatttt gcagctgtac
     4081 gctcgccatg cccttctccc tttgtaacaa cctgtcatcg acagcaacat tcatgatggg
     4141 ctgactatgc gtcatcagga gatggcttaa atcctccacc ccctggcttt tttatggggg
     4201 aggaggcggg aggatgagaa cacggcttct gtgaactaaa ccgaggtcat gtaaggaatt
     4261 tcgtgatgtt gcttgcaaaa atcgtggcga ttttatgtgc gcatctccac attaccgcca
     4321 attctgtaac agagatcaca caaagcaacg gtggggcgta ggggcaagga ggatggaaag
     4381 aggttgccgt ataaagaaac tagagtccgt ttaggtgttt tcacgagcac ttcaccaaca
     4441 aggaccatag attatgaaaa taaaaacagg tgcacgcatc ctcgcattat ccgcattaac
     4501 gacgatgatg ttttccgcct cggctctcgc caaaatcgaa gaaggtaaac tggtaatctg
     4561 gattaacggc gataaaggct ataacggtct cgctgaagtc ggtaagaaat tcgagaaaga
     4621 taccggaatt aaagtcaccg ttgagcatcc ggataaactg gaagagaaat tccctcaggt
     4681 tgcggcaact ggcgatggcc ctgacattat cttctgggcg cacgaccgct ttggtggcta
     4741 cgctcaatct ggcctgttgg ctgaaatcac cccggacaaa gcgttccagg acaagctgta
     4801 tccgtttacc tgggatgccg tacgttacaa cggcaagctg attgcttacc cgatcgctgt
     4861 tgaagcgtta tcgctgattt ataacaaaga tctgctgccg aacccgccaa aaacctggga
     4921 agagatcccg gcgctggata aagaactgaa agcgaaaggt aagagcgcgc tgatgttcaa
     4981 cctgcaagaa ccgtacttca cctggccgct gattgctgct gacgggggtt atgcgttcaa
     5041 gtatgaaaac ggcaagtacg acattaaaga cgtgggcgtg gataacgctg gcgcgaaagc
     5101 gggtctgacc ttcctggttg acctgattaa aaacaaacac atgaatgcag acaccgatta
     5161 ctccatcgca gaagctgcct ttaataaagg cgaaacagcg atgaccatca acggcccgtg
     5221 ggcatggtcc aacatcgaca ccagcaaagt gaattatggt gtaacggtac tgccgacctt
     5281 caagggtcaa ccatccaaac cgttcgttgg cgtgctgagc gcaggtatta acgccgccag
     5341 tccgaacaaa gagctggcga aagagttcct cgaaaactat ctgctgactg atgaaggtct
     5401 ggaagcggtt aataaagaca aaccgctggg tgccgtagcg ctgaagtctt acgaggaaga
     5461 gttggcaaaa gatccacgta ttgccgccac catggaaaac gcccagaaag gtgaaatcat
     5521 gccgaacatc ccgcagatgt ccgctttctg gtatgccgtg cgtactgcgg tgatcaacgc
     5581 cgccagcggt cgtcagactg tcgatgaagc cctgaaagac gcgcagactc gtatcaccaa
     5641 gtaatgctgt gaaatgccgg atgcggcgtg aacgccttgt ccggcctaca aaaccgaaac
     5701 gtatgtaggc ctgataagac gcgtcagcgt cgcatcaggc agttgttgtc ggataaggcg
     5761 tgaaagcctt atccgtcctg gaatgaggaa gaaccccatg gatgtcatta aaaagaaaca
     5821 ttggtggcaa agcgacgcgc tgaaatggtc agtgctaggt ctgctcggcc tgctggtggg
     5881 ttaccttgtt gttttaatgt acgcacaagg ggaatacctg ttcgccatta ccacgctgat
     5941 attgagttca gcggggctgt atattttcgc caatcgtaaa gcctacgcct ggcgctatgt
     6001 ttacccggga atggctggaa tgggattatt cgtcctcttc cctctggtct gcaccatcgc
     6061 cattgccttc accaactaca gcagcactaa ccagctgact tttgaacgtg cgcaggaagt
     6121 gttgttagat cgctcctggc aagcaggcaa aacctataac tttggtcttt acccggcggg
     6181 cgatgagtgg caactggcgc tcagcgacgg cgaaaccggc aaaaattacc tctccgacgc
     6241 ttttaaattt ggcggcgagc aaaaactgca actgaaagaa acgaccgccc agcccgaagg
     6301 cgaacgcgcg aatctgcgcg tgattaccca gaatcgtcag gcgctgagtg acattaccgc
     6361 cattctgccg gatggcaaca aagtgatgat gagctccctg cgccagtttt ctggcacgca
     6421 gccgctctac acactcgacg gtgacggcac gttgacgaat aatcagagcg gcgtgaaata
     6481 tcgtccgaat aaccaaattg gcttttacca gtccattacc gccgacggca actggggtga
     6541 tgaaaagcta agccccggtt acaccgtgac caccggctgg aaaaacttta cccgcgtctt
     6601 taccgacgaa ggcattcaga aaccgttcct cgccattttc gtctggaccg tggtgttctc
     6661 gctgatcact gtctttttaa cggtggcggt cggcatggtt ctggcgtgtc tggtgcagtg
     6721 ggaagcgttg cgcggcaaag cggtctatcg cgtcctgctg attctgccct acgcggtgcc
     6781 atcgttcatt tcaatcttga ttttcaaagg gttgtttaac cagagcttcg gtgaaatcaa
     6841 catgatgttg agcgcgctgt ttggcgtgaa gcccgcctgg ttcagcgatc cgaccaccgc
     6901 ccgcacgatg ctaattatcg tcaatacctg gctgggttat ccgtacatga tgatcctctg
     6961 catgggcttg ctgaaagcga ttccggacga tttgtatgaa gcctcagcaa tggatggcgc
     7021 aggtccgttc cagaacttct ttaagattac gctgccgctg ctgattaaac cgctgacgcc
     7081 gctgatgatc gccagcttcg cctttaactt taacaacttc gtgctgattc aactgttaac
     7141 caacggcggc ccggatcgtc ttggcacgac cacgccagcc ggttataccg acctgcttgt
     7201 taactacacc taccgcatcg cttttgaagg cggcgggggt caggacttcg gtctggcggc
     7261 agcaattgcc acgctgatct tcctgctggt gggtgcgctg gcgatagtga acctgaaagc
     7321 cacgcgaatg aagtttgatt aagggagata acaaaaatgg caatggtcca accgaaatcg
     7381 caaaaagctc gtttatttat tactcacctg ctactgctac tttttatcgc agcgattatg
     7441 ttcccgctgc tgatggtcgt cgctatctcg ctgcgtcagg gaaactttgc gaccggcagc
     7501 ctgatcccgg agcaaatctc ctgggatcac tggaaactgg cgttaggttt tagcgttgaa
     7561 caggctgatg gtcgcattac gccaccgcca ttcccggtac tgctgtggct gtggaactcg
     7621 gtaaaggtcg ccgggatttc cgcgattggc attgtggcgc tctccaccac ctgcgcctac
     7681 gctttcgccc gtatgcgctt tccaggcaaa gcgacgctgc tgaaaggaat gctgattttc
     7741 cagatgttcc cggcagtact ttcactggtc gcgttgtatg cgttgtttga tcgtctgggt
     7801 gagtacattc cattcattgg cctgaatact cacggcggcg taattttcgc gtatctgggt
     7861 gggattgcgc tgcatgtctg gaccatcaaa ggctatttcg aaaccatcga cagttcgctg
     7921 gaagaagctg ctgcgctgga tggtgcgaca ccgtggcagg ccttccgcct tgtcctgttg
     7981 ccgctgtcag taccgattct ggcggtggta ttcatcctgt cgtttatcgc tgccattact
     8041 gaagttccgg tcgcgtcgct gttactgcgt gacgtaaaca gctacaccct ggccgtgggg
     8101 atgcagcaat acctcaaccc gcaaaactac ctgtggggtg actttgccgc cgctgccgtg
     8161 atgtctgcat taccgatcac catcgtcttc ttgctggctc aacgctggct ggtcaacggc
     8221 ctgacggcag gtggtgtgaa aggttaaaga tgttgttctg ccaatgttat gccgctgcac
     8281 cctcaactta cgttatccca acttgtgact gttattcggc gctccacgga gcgccttttt
     8341 ttctttcgtc tgcaatctga atcgttcgcc ggttaatatt tccatcatag agcttattat
     8401 ttttacgtta tttgttttcc cacttacgat aattctcttt cgtgctctga gtcacggcaa
     8461 tagtattgtt tttatcaatt ttggataatt atcacaatta agatcacaga aaagacatta
     8521 cgtaaacgca ttgtaaaaaa tgataattgc cttaactgcc tgacaattcc aacatcaatg
     8581 cactgataaa agatcagaat ggtctaaggc aggtctgaat gaatacccag tataattcca
     8641 gttatatatt ttcgattacc ttagtcgcta cattaggtgg tttattattt ggctacgaca
     8701 ccgccgttat ttccggtact gttgagtcac tcaataccgt ctttgttgct ccacaaaact
     8761 taagtgaatc cgctgccaac tccctgttag ggttttgcgt ggccagcgct ctgattggtt
     8821 gcatcatcgg cggtgccctc ggtggttatt gcagtaaccg cttcggtcgt cgtgattcac
     8881 ttaagattgc tgctgtcctg ttttttattt ctggtgtagg ttctgcctgg ccagaacttg
     8941 gttttacctc tataaacccg gacaacacag tgcctgttta tctggcaggt tatgtcccgg
     9001 aatttgttat ttatcgcatt attggcggta ttggcgttgg tttagcctca atgctctcgc
     9061 caatgtatat tgcggaactg gctccagctc atattcgcgg gaaactggtc tcttttaacc
     9121 agtttgcgat tattttcggg caacttttag tttactgcgt aaactatttt attgcccgtt
     9181 ccggtgatgc cagctggctg aatactgacg gctggcgtta tatgtttgcc tcggaatgta
     9241 tccctgcact gctgttctta atgctgctgt ataccgtgcc agaaagtcct cgctggctga
     9301 tgtcgcgcgg caagcaagaa caggcggaag gtatcctgcg caaaattatg ggcaacacgc
     9361 ttgcaactca ggcagtacag gaaattaaac actccctgga tcatggccgc aaaaccggtg
     9421 gtcgtctgct gatgtttggc gtgggcgtga ttgtaatcgg cgtaatgctc tccatcttcc
     9481 agcaatttgt cggcatcaat gtggtgctgt actacgcgcc ggaagtgttc aaaacgctgg
     9541 gggccagcac ggatatcgcg ctgttgcaga ccattattgt cggagttatc aacctcacct
     9601 tcaccgttct ggcaattatg acggtggata aatttggtcg taagccactg caaattatcg
     9661 gcgcactcgg aatggcaatc ggtatgttta gcctcggtac cgcgttttac actcaggcac
     9721 cgggtattgt ggcgctactg tcgatgctgt tctatgttgc cgcctttgcc atgtcctggg
     9781 gtccggtatg ctgggtactg ctgtcggaaa tcttcccgaa tgctattcgt ggtaaagcgc
     9841 tggcaatcgc ggtggcggcc cagtggctgg cgaactactt cgtctcctgg accttcccga
     9901 tgatggacaa aaactcctgg ctggtggccc atttccacaa cggtttctcc tactggattt
     9961 acggttgtat gggcgttctg gcagcactgt ttatgtggaa atttgtcccg gaaaccaaag
    10021 gtaaaaccct tgaggagctg gaagcgctct gggaaccgga aacgaagaaa acacaacaaa
    10081 ctgctacgct gtaatcttcc tgtccagcac gccgcgccat ttcggcgtgc tgacttttta
    10141 ctcccgcttc agccgtttcg aattacacag ccacagggtg atcaccagta acaggatcgc
    10201 agccgagtag atcaacacat ccagtggcga tttatgatcg acgatgatca agcgcacaat
    10261 ggcggtgatc ccaatataga caaagtaacg tagcgggaag tgaaaaccgg actgaaagta
    10321 cttcacaatc agcgcgataa attcgaaata gagaaagtaa accaccagtc cttctaccag
    10381 ctcatatttg ctggtttgtt ctggcgcgaa cagcacatca gccagatgca ccgtttcttt
    10441 gccgaggaag acaaccaaaa tcaggccgag gcacagcagg ccaagattga gtacggtctg
    10501 caaaatggtg gagataaact ccacgcgcgg acgagagagt gacgtcatag cagtacctcc
    10561 ttcacagtgg cgagcttcct gtataacgca aaaatgtgac ggagatctat attttttgtg
    10621 tatgttttgt tcaacctgga tttggagcgc gcctccacca aagccggata tacctacccg
    10681 taggccggat aagccgcgcc tggcggcgca tccggcaaga caaaccgcac caaagccggt
    10741 aattcaaaaa tcacccattc aggtgattcc cagccaccag caatgcgcga aaaatcgaca
    10801 atgttcctct ggaacaaatg aaacgtaacc tgataaaggt ggtaaaaatg aagccttatt
    10861 ttgctgcttt gatgttatca gtctctgttc ttcctgctta tgctggtccg ctcggtactg
    10921 ctgataaagc cgacctaccg caaagcaatg tctccagccc aatgatggcc cagtcgctca
    10981 ggcaaccaga cctgcaaccg atatcgacgg acaggaagac agaatgtttt cgcctttaca
    11041 caccagatcg caaaccgggg gtgaactgcg ttcctgatgg ctcaacaggc cattaagaat
    11101 gagggtgcca gtgattgcga aaactggcac ctttcccatg acttagcgga aattgacgct
    11161 acggtcgctg gtcatgtcat acaactggaa cttacgccca agttgttgac caccgtcacg
    11221 cgtcagcggc gtccagccaa tcgccgcacg gctgcgtgtc gggccagacg agaagagatc
    11281 caacggtacc gagacataca cgcctttggt gaagtcccct tcgccgtact cctctttcga
    11341 aacattagtg atcgtggcat agccacccac caccacgccg ctatcaaagc gtttggcgat
    11401 ctccagcgtg ccgcctttat cccctgccag atactgcccg acgctggctt taactaacac
    11461 atcctgagcg aaagatggcg tccagtaggc ggtcagatgt ccggttttca cgctgtagtc
    11521 ggtgaatttc atcatatctt ttgcactacg ccagtcgcgc tgtttaacgt agttggcatc
    11581 cagaccaaac gcccagttgc tgtccagcgg gcgatacaac acttctgccc ccgcaccgcc
    11641 aaacatggtt tcgagataac caccgtagac ctgaccgtag aagccgttgc ccagatgctg
    11701 gaagtagttg gcttgcaggt tattcacata gacatcgttc tgcacatact cgcgcacatg
    11761 ggtacgcacg cgcggtaagt gcgagtcctg cggaggatta gtgtagttaa acttgtcgta
    11821 gttgttggca agatttgcaa acaggctgcc ggtggtcagc agatggtccg tcagccacaa
    11881 atctgccgtt cccatcacgc ccagctgata catgtaaaag ttttccgggc caccgaccga
    11941 ctggttcagc accggatcga tatggaaatc aaagcgtgat ttgtcgatat accagccctg
    12001 ctcggtggac tgcggaacca ctggctcgac gcgtttttgc gccagcgtcg tttcgtggcc
    12061 caacggctct ccggcgagat gatttttcag gctggcgaca tcggtttccg tcgtcgcctg
    12121 cggcatgtta aggcgatttt ccgtaatgcg gatcgttttg atcccatccg gcagatcgtt
    12181 catcacgatc cgattcgcac ggatgatccc ttcgcgcgaa tcacgatatt tcacctgctc
    12241 gccggtaaca tacagcgtat cgcctttcgc ctggatctgt ggatcggcaa gtccggcatt
    12301 gtatttcaac agcgttaact gattcgccac caccgaatgc tgcaaaatgg catcctgcgg
    12361 ctgcggttga tattgcgggc gggcgttatc gttgtaagac gggcgcagat cgttaaagtt
    12421 ggtgcgcaac gtaacgccaa acataaaggt gttgccacgt tcatagctaa ggttaacgtc
    12481 ggcccaatcg gtaacgcgat aaatcgcacc gacgttaaac ttactttttt gctccagctt
    12541 cccggcaaaa tcctgctgat aattattgcc ttcatactcc agtttcaggc gcagcggttg
    12601 ccagggcgtc tggtattcca cgccgccaaa cagtgaggca ggaccgtgga acatctggct
    12661 accgtcgata gatcccgcct gtttgtagct gttatcgcga tagcaatatt tatcactggc
    12721 tgaacagagc ggatttttca cattaccgct ggtgcccaaa tatccccagc ccaggccgag
    12781 cgtaaaatcg aacggccccc aggctttgct ggcaacaaga tattccgcat caaacagccc
    12841 cgtaccgccg atatcccgcg caccaaccgc cacttgcggc agccagtaac tctcttccca
    12901 caaacgcagt ttgagatcga aggctttatc tttatacgtt tgatcgccag agaacgcttc
    12961 gacgctgctg tactgccggg tgcgcacgtc ggtgtagcgc agcgttgttt ccagccacgg
    13021 gaagagttgc actgaagctg agtaataacg gtactgatcg ttatcgcgat agttcaggct
    13081 caactcccct tcccgcgcca tgcgtgcggt gggcgtttgt aataatccta cgccaccgaa
    13141 atccgactgc gacgggccaa tgggcgcagg atatgtttcg ccgtagcaag ccatgctaat
    13201 gcccagcgcc agtaagctaa gcagatgtct ttttttcatt attgaggtat ccgctgcgtc
    13261 agagtctgaa gaatgtcggc gttaagggca tcaggcgtct cactccagac ggagtccgcg
    13321 aggccaacat aaataatgct gccgggcatc ggctctacgt gacgcttgtt ccagtaagcc
    13381 accggcgctt tttgcgtgcg tccgtccggg taaaccaccc acgcgtagct gcgatccgca
    13441 ccgctgagca ggctctggtc agagagatag ctcgccacgt cgcgacctgg agtgaatggc
    13501 tgcttgccag gacggctgat aagcccgaac aacgtgaccg tggacggcgg tggtccgacc
    13561 cacagcgtgt agttgccctg caacggcggg ttaccgcgtt cggcaacgcg gacgatatcg
    13621 ggatcaagat tgattttttg cctgcccgtc actttcaacg cctgaatttg ctggcgtaag
    13681 gcgttaatcg cagcggcatc gtcggcgctg gaatctgcgc cctgttctgc cagccgtgtc
    13741 agcaacgcct gctgctgacg caatgctgcc gccgttgcca gctcttcgct aatcaccgca
    13801 ccgggccacc agctgtttgc cagccgcggt tggcctacca gatcgattaa atgctctgcg
    13861 cccgttagcg ttttggcctc actgctgcca ttgctgaaca ccttgacggt tcctgccgcg
    13921 aagaccgatg acgctcccac actcaaaagc aacgcgacaa tagtttgttt aatcattgtt
    13981 ttgccgcctt gatgagagtg gttttcaccg gaaaataatc cgcgccgaga tactgttccg
    14041 actggcgaat ttgcccttcg ctgtcgatcc aatagcggtt atgccagcgc gcctggtcgg
    14101 tggagacttc ttcgtccagc acgcgaaccg gggtttcatc gctgccgact ttgacggtat
    14161 cggtgccatc ccatttgaag actgagcgtg cggtggcgta gcgtacctgc tggtactcgg
    14221 tccagcccat cgtgcgcgtc cagcttgcgc catcaacgat ttgtgcgggt ttaatcagcg
    14281 ggtcggcagc aaggttattc acttcaatca ggttgtcgcc gccgagcaga gtcttcacca
    14341 gacggccatg ttgggtaacg agagtagcct gatcctgagt gacccatttt tgttgtccgt
    14401 cttcagcgaa ggccagcacc acaaataact gcggcccgcc attaagctgc atgtactggc
    14461 tggcgtaggg catattttga atatcatcat ccgtcagctg tacgcctggc gggccgaaca
    14521 gactgtccca cagtgaattg cccagctctt tagtcgtggc tgaacaggcc tgtaatagca
    14581 ggcagataag aatgagtgca ggtcgcttca cgactcttct ccagaggggc agaataacca
    14641 caccggagtg tggttatggt aaatcccttc atacttcaag ccacagatgc aatgactcaa
    14701 attattttgg ggatacatac tttattactg ggtactggtg gtcgtggttg tggtggtccc
    14761 ggtattagaa ccatcaccgc caccggttgc cgcgagcgcg acacccaccg ccgagcttac
    14821 ggtgctgacg ctggtcgcgg aggaactccc cgccgaaacc gacgttgctg ccgaccctgc
    14881 cgcttcgccc acctgtacag gtgcagccca cgcagaagtc gccgcaagcg cagatatggc
    14941 aaaaatgcca tacagaactt ttttcataac aatttccctt cattgaatga atggagattt
    15001 acccaaaaac atttcgggcg ggatcgagta tacacaacta aagcatgcga attacggcgc
    15061 ggggaa
//
LOCUS       DAPHKZ010000108        15033 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.108, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000108 DAPHKZ010000000
VERSION     DAPHKZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15033
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.108"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(60..2339)
                     /gene="maeB"
                     /locus_tag="RH288_003488"
     CDS             complement(60..2339)
                     /gene="maeB"
                     /locus_tag="RH288_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HDV4032510.1"
                     /translation="MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVV
                     CDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEG
                     EEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDYHEHFSV
                     VKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFG
                     IEPRVALLSHSNFGSSDCPSSSKMRQALELVRERAPELMIDGEMHGDAALVEAIRNDR
                     MPDSSLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASV
                     RRIVNMVALAVVEAQTQPL"
     gene            2628..3578
                     /gene="tal"
                     /locus_tag="RH288_003489"
     CDS             2628..3578
                     /gene="tal"
                     /locus_tag="RH288_003489"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDV4032511.1"
                     /translation="MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGL
                     SQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
                     AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYE
                     TIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMS
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            3598..5601
                     /gene="tkt"
                     /locus_tag="RH288_003490"
     CDS             3598..5601
                     /gene="tkt"
                     /locus_tag="RH288_003490"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDV4032512.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGH
                     DPQAVKEAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKL
                     GWHHPPFEIPKEIYHVWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPK
                     DWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGS
                     VSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVER
                     HNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQA
                     AEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVAARVAVEAGIADYWYKYVGL
                     KGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA"
     gene            complement(5696..6739)
                     /locus_tag="RH288_003491"
     CDS             complement(5696..6739)
                     /locus_tag="RH288_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HDV4032513.1"
                     /translation="MRYRIFLLFFFALLPTSLVWAAPAQRAFSDWQVTCNNQNFCVAR
                     NTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPEASEGEIAPRLLLDGEPLALSGDK
                     WRISPWLLVTDDTATITAFLQMIQEGKAITLRDGDQTISLSGLKAALLFIDAQQKRVG
                     SETAWIKKGDEPPLSVPPAPALKEVAVVNPTPTPLSLEERNDLLDYGNWRMNGLRCSL
                     DPLRREVNVTALTDDKALMMISCEAGAYNTIDLAWIVSRKKPLASRPVRLRLPFNNGQ
                     ETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRFRLVRYAAEPTCDNW
                     HGPDAWPTLWITR"
     gene            complement(6865..7440)
                     /gene="nudK"
                     /locus_tag="RH288_003492"
     CDS             complement(6865..7440)
                     /gene="nudK"
                     /locus_tag="RH288_003492"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HDV4032514.1"
                     /translation="MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDR
                     GNGATILLYNTKKKTVVLIRQFRVATWVNGNESGQLIESCAGLLDNDEPEVCIRKEAI
                     EETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDNQRANAGGGVEDEDIEVLELPF
                     SQALEMIKTGEIRDGKTVLLLNYLQTSHLMD"
     gene            complement(7508..9487)
                     /gene="aegA"
                     /locus_tag="RH288_003493"
     CDS             complement(7508..9487)
                     /gene="aegA"
                     /locus_tag="RH288_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     AegA"
                     /protein_id="HDV4032515.1"
                     /translation="MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITV
                     IKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTM
                     QIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDVALSGMAKFRRLR
                     TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRAD
                     QAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITG
                     RVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSHVTKVDKRVAIIG
                     AGPAGLACADVLTRNGVGVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGI
                     HFELNCEVGKDVSLDSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTK
                     QVMGLEELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPG
                     SKKEVKNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTRLGEPDAQGRRRPVPVEG
                     SEFVMPADAVIMAFGFNPHGMPWLESHGVTVDKWGRIIADVESQYRYQTTNPKIFAGG
                     DAVRGADLVVTAMAEGRHAAQGIIDWLGVKSVKSH"
     gene            9693..11393
                     /gene="narQ"
                     /locus_tag="RH288_003494"
     CDS             9693..11393
                     /gene="narQ"
                     /locus_tag="RH288_003494"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HDV4032516.1"
                     /translation="MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHL
                     NANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
                     IFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTNLPNELGLLAKTFNQM
                     SSELHKLYRSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRD
                     NEAAEYLELNVGENWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLN
                     SVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIP
                     EDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAK
                     LTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRD
                     NGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
                     "
     gene            11557..14670
                     /gene="acrD"
                     /locus_tag="RH288_003495"
     CDS             11557..14670
                     /gene="acrD"
                     /locus_tag="RH288_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HDV4032517.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVR
                     VTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYD
                     YLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHGLEYKVAYETTSFVK
                     ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ
                     KGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLE
                     DRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVA
                     RMFIRLKDWSERDSKTGTSFAIIERATKAFNQIKEARVIASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVA
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF
                     PLKPRPE"
     gene            complement(14769..14828)
                     /gene="ypfM"
                     /locus_tag="RH288_003496"
     CDS             complement(14769..14828)
                     /gene="ypfM"
                     /locus_tag="RH288_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpfM"
                     /protein_id="HDV4032518.1"
                     /translation="MIERELGNWKDFIEVMLRK"
BASE COUNT         3523 a         3993 c         3918 g         3599 t
ORIGIN      
        1 atattgcagc taaactgctt accctgaata ttcagggtaa gcgtgagagt taaaaaaaat
       61 tacagcggtt gggtttgcgc ttctaccacg gccagcgcca ccatgttgac gatacgacgc
      121 accgatgcga tcggcgttaa cacgtgaacc ggtttcgcca cacccatcag caccgggccg
      181 acagtcacac cttccgagct ggaaacacgc agtaagttgt aactaatgcg ggcagcttcc
      241 atgttcggca tcaccagaat attggcggaa cctttcaaag agctgtccgg catacggtcg
      301 ttgcgaatcg cttccaccag cgctgcatcg ccgtgcattt caccatcaat catcagttct
      361 ggtgcacgtt ccctgaccag ttccagcgcc tgacgcattt tgctcgacga cgggcagtca
      421 gaagaaccaa agttggagtg cgacaacaaa gcaacgcgcg gctcaatacc aaaacgacgg
      481 acagtttctg ccgccatcaa ggtgatctcc gccagctctt ctgcatccgg ttcatcatta
      541 acatatgtat cggcaataaa ggtgttacca ctcggcagca gcagcgcgtt catggcacct
      601 gcggtgtgaa cgccatcgcg ataaccaaag acatttttca ccacgctaaa atgttcatga
      661 taatcaccca ccgtaccgca aatcattgca tcggcttccc cacgctgaac catgatcgcg
      721 ccgatcactg tcgggttact gatcagcgcc cgctgcgcct gttcctgagt gacgccgcga
      781 cgcttcatga tctggaagta ttcggtccag tactctttaa agcgcggatc ggattcgtta
      841 ttgacgatct caaaatcaac gcccgctttg atctgcaagc ccagtttctg aatgcgcatt
      901 tcgatcacgt tcggacgacc gataaggatc ggtttcgcca gtcccagcgt taccagttcc
      961 tgagtggcat gcagaacgcg cgcctcttcc ccttccggca gaacaacgcg cttcggcgct
     1021 ttgcgagcct gggagaaaat cggcttcata aacaggttgg ttttgtaaac gaactcagtc
     1081 agcttgtcga tgtagacgtc gaaatcagca atcggacgag tcgccacgcc cgactccatc
     1141 gcggctttag cgaccgcagg agcgatctta acgatcaagc gcggatcaaa cggttttgga
     1201 atgatgtatt ccggaccaaa gctcagatcc tgatcgccat acgctgaagc caccacttcg
     1261 ctctgttccg catgggcgag ttctgcaatc gcacgtaccg ccgccagttt catctcttcg
     1321 ttgatggcgg ttgcgccaac gtccagcgcg ccacggaaga tgaacgggaa gcacaggacg
     1381 ttgttcacct ggttcggata gtcagaacga ccggtgcaaa tgatggcatc cggacgcact
     1441 tctttcgcca gcggcggcag aatttccggt tccgggttcg ccagcgccag gatcattggc
     1501 gcacgagcca ttttcttcac catttcctgg gtcagcactt tcgggccgga acagcccagg
     1561 aaaatatccg cgccttcaat cacatcatcg agggtacgtt tgccgtcatc caccaccgca
     1621 tatgcggctt tggtttccgc catgtttggc tcacggccct gatagataac gccttttgaa
     1681 tcgcaaacca cgatgttatg tttttgcaga cccagcgcta ccagcaggtt catacaggcg
     1741 attgctgcgg cacccgcgcc ggaaaccacc atccgcacgt cggagatgtt tttctccacc
     1801 acgcgcaagc cgttgaggat ggcggcagtg ctgataattg ccgtgccgtg ctgatcgtcg
     1861 tggaataccg gaatattcat ccgctcgcgc agtttctgtt caatatagaa acattctggc
     1921 gctttaatgt cttcgaggtt gatgccgccg aaggttggtt cgagcgcggc gacaacttca
     1981 ataaatttgt ccgggtcgag ttcgtcaact tcaatgtcaa atacatcaat cccggcgaat
     2041 ttcttaaaca gaacgccctt gccttccatc accggtttgc ctgccagcgc gccaatgttg
     2101 cctaacccca gcaccgccgt accgttagag atcaccgcca ccaggttacc gcgggcggta
     2161 tatttgtagg cttttaacgg gtctttttcg atttcaagac aaggtgcggc aacgcctggt
     2221 gagtaggcca gcgccagatc gcgctgtgtt gccagaggct tggttggaga aacctggatt
     2281 ttccctggaa ctggaaattc atggaaatca agtgcacttt gttttaactg gtcatccatt
     2341 tggttgttcc tttcacgtaa cgttcacaaa taaagtgtgt gggcaacagc ccctgcccac
     2401 aacgtggcgc acattattac cctgccggag tctacagact ttgagcaagt ccaaactctc
     2461 accattaata taatgttttg gtaataatcc tataacactg atgttacctg cttaatccag
     2521 caataccatg cctgtctgct atgctttttt gatgcgttta gcgaaatttc tcagaagtgt
     2581 gaattaacgc actcatctaa cactttactt ttcaaggagt atttcctatg aacgagttag
     2641 acggcatcaa acagttcacc actgtcgtgg cagacagcgg cgatattgag tccattcgcc
     2701 attatcatcc ccaggatgcc accaccaatc cttcgctgtt actcaaagct gccggattat
     2761 cacaatatga gcatttaata gacgatgcta tcgcctgggg taaaaaaaat ggcaagaccc
     2821 aggaacaaca ggtggtcgca gcgtgtgaca aactggcggt caatttcggt gctgaaatcc
     2881 tcaaaatcgt acccggtcgc gtgtcaacag aagttgatgc acgcctctct tttgataaag
     2941 aaaagagtat tgagaaggcg cgccatctgg tggacttgta tcagcaacaa ggcgttgaga
     3001 aatcacgcat tctgatcaag ctggcttcga cctgggaagg aattcgcgcg gcagaagagc
     3061 tggaaaaaga aggtattaac tgcaacctga cgctgctgtt ttcttttgca caggcacggg
     3121 cctgtgcgga agcaggcgtt tttctgattt cgccgtttgt cgggcgtatt tatgactggt
     3181 atcaggcacg caagccgatg gacccgtatg tggtggaaga agatccgggc gttaaatcgg
     3241 tgcgcaatat ctacgactac tataagcaac accactatga aaccattgtg atgggcgcga
     3301 gcttccgtcg caccgaacaa atcctcgcct taaccggctg cgatcgactg actatcgcac
     3361 cgaatttact gaaggagctg caggaaaaag tttcgccagt ggtacgtaaa ttaatcccac
     3421 cttctcagac gttcccacgc ccagctccca tgagcgaagc ggagttccgt tgggagcaca
     3481 atcaggatgc gatggcggta gaaaaactgt ctgaaggcat tcgtctgttc gccgttgatc
     3541 aacgcaaact ggaagatctt cttgccgcca aactataaac cagccacgga gtgttatatg
     3601 tcccgaaaag accttgccaa tgcgattcgc gcactcagta tggatgcggt acaaaaagcc
     3661 aactctggtc atcccggcgc gccgatgggc atggctgata ttgccgaagt gctgtggaac
     3721 gattttctta aacataaccc taccgaccca acctggtatg atcgcgaccg ctttattctt
     3781 tccaacggtc acgcgtcgat gctgctctac agtttgctac atctgaccgg ttacgacctg
     3841 ccgctggaag aactgaagaa cttccgtcag ttgcattcga aaaccccagg ccacccggag
     3901 attggctata cgccaggcgt tgaaaccacc accggcccgc ttggacaagg tttggcgaac
     3961 gccgtcgggc tggcgatagc agagcgtaca ctggcggcgc agtttaacca gccagaccat
     4021 gagatcgtcg atcacttcac ctatgtgttt atgggcgacg gctgcctgat ggaaggtatt
     4081 tcccacgaag tctgttcgct ggcaggcacg ctgggactgg gcaagctgat tggtttttac
     4141 gatcacaacg gtatttccat cgacggtgaa acagaaggct ggtttaccga cgatacggca
     4201 aaacgttttg aagcctatca ctggcatgtg atccatgaaa tcgacggtca cgatccgcag
     4261 gcggtgaagg aagcgatcct tgaagcgcaa agcgtgaaag ataagccgtc gctgattatc
     4321 tgccgtacgg tgattggctt tggttcgccg aataaagcag gtaaggaaga ggcgcacggc
     4381 gcaccactgg gggaagaaga agtggcgctg gcacggcaaa aactgggctg gcaccatccg
     4441 ccatttgaga tccctaaaga gatttatcac gtctgggatg cccgtgaaaa aggcgaaaaa
     4501 gcgcagcaga gctggaatga gaagtttgcc gcctataaaa aggctcatcc gcaactggca
     4561 gaagagttta cccgacggat gagcggtggt ttaccgaagg actgggagaa aacgactcag
     4621 aaatatatca atgagttaca ggcaaatccg gcgaaaatcg ctacccgtaa ggcttcgcaa
     4681 aatacgctta acgcttacgg gccgatgctg cctgagttgc tcggcggttc ggcggatctg
     4741 gctcccagca acctgaccat ctggaaaggt tctgtttcgc tgaaggaaga tccagcgggc
     4801 aactacattc actacggggt gcgtgaattt ggcatgaccg ctatcgccaa cggcatcgcg
     4861 caccacggcg gctttgtgcc gtataccgcg acgttcctga tgtttgttga atacgcccgt
     4921 aacgccgcgc ggatggcggc actgatgaaa gcgcggcaga ttatggttta tacccacgac
     4981 tcaattggcc tgggcgaaga tggtccgacg caccaggctg ttgagcaact ggccagcctg
     5041 cgcttaacgc caaatttcag cacctggcga ccgtgcgatc aggtggaagc ggcggtgggc
     5101 tggaagctgg cggttgagcg ccacaacgga ccgacggcac tgatcctctc aaggcagaat
     5161 ctggcccagg tggaacgtac gccggatcag gttaaagaga ttgctcgtgg cggttatgtg
     5221 ctgaaagaca gcggcggtaa gccagatatt attctgattg ccaccggttc agagatggaa
     5281 attaccctgc aagcggcaga gaaattagca ggagaaggtc gcaatgtacg cgtagtttcc
     5341 ctgccctcga ccgatatttt cgacgcccag gatgaggaat atcgggagtc ggtgttgcct
     5401 tctaacgttg cggctcgcgt ggcggtggaa gcaggtattg ccgattactg gtacaagtat
     5461 gttggtctga aaggggcaat tgtcgggatg acgggttacg gagaatctgc tccggcggat
     5521 aagctgttcc cgttctttgg ctttaccgcc gagaatattg tggcaaaagc gcataaggtg
     5581 ctgggagtga aaggtgcctg atggtgattg ccggatgctg attgccggat gcgacgctga
     5641 cgcgtcttat ccggcctaca gcgtcttatc cggcctacat gtcccgccat tttgtttaac
     5701 gggtgatcca caacgtgggc caggcgtctg gcccatgcca gttatcgcag gtgggttctg
     5761 cggcgtaacg caccaggcga aaacgctgac cgtcaaagcg ccagcgcgcc tgaatgccac
     5821 aatcgcttaa tccgcgccct ttcgctaagg tcaccagttc acgcgatttc tcatcaaatg
     5881 ttgcgttcat cagttccagt tcattcgtct cctgaccgtt gttgaacggc aaacgcaacc
     5941 gaaccgggcg cgaagctagt ggctttttac gcgacacaat ccatgccaaa tcaatggtgt
     6001 tataggcccc tgcctcacag ctaatcatca tcagcgcttt atcatcagtc agcgcagtga
     6061 cattcacctc acgacgcaat ggatcaagcg agcagcgcag accattcatc cgccagtttc
     6121 cataatccag caaatcgttg cgttcttcga gtgagagtgg cgtcggcgtt gggttaacca
     6181 ccgcgacctc tttcagcgca ggcgcgggcg gtacgctgag cggcggttcg tcccctttct
     6241 tgatccacgc ggtttcactg ccaacgcgct tttgctgagc atcaataaac aacaacgctg
     6301 cttttaagcc actcagagaa atggtctgat cgccatcgcg taaggtgatt gccttccctt
     6361 cctgaatcat ctgcaaaaac gcggtgatgg ttgccgtatc atcggttact aataaccatg
     6421 gtgaaatccg ccacttgtca ccacttaacg ccaacggctc gccatctaac agcagccgtg
     6481 gcgctatctc cccttctgac gcctccggcg acttcaatcc gccgcgctca atacgtaaaa
     6541 cggcatcggt atgcgccccg gcgctgcggc tcagggtcat caccagtcca ttatgatcgc
     6601 ccgtattacg cgccacgcag aaattttggt tattacaggt gacctgccag tcggaaaacg
     6661 cccgttgcgc tggtgccgcc cacaccaaag acgtcggcaa caaagcgaaa aaaaagagaa
     6721 ggaaaatgcg atagcgcatg gacggtacga ccccagaagt tcaaacaaac agcacaagtc
     6781 gtatcttcgt tgcgcaggta gcgcggctca atcggatttg tcggattgag ccaataataa
     6841 acaacgaaat attattgtta tttttcagtc cattaaatgt gacgtttgca aatagttaag
     6901 caataacacc gtcttaccgt cacgtatctc gccggttttg atcatctcca gcgcctggct
     6961 gaacggcagc tcgagcactt caatatcttc atcttcgaca ccgccaccgg cgttagcgcg
     7021 ctgattgtca ctgtattcgg cgataaaaaa gtggattagc tcagtcacac cgcctggcga
     7081 catatacagt tcaaataatt tgcgcacttc acccacttca tagcccgtct cttcaatcgc
     7141 ttctttgcga atacacactt ccggttcgtc gttatccagc agcccggcgc agctttcaat
     7201 cagctgcccg ctttcattgc cattaaccca ggtagcgaca cggaactgac gaatcagaac
     7261 cacggtcttt ttcttcgtgt tgtacaggag gatcgtcgca ccattgccgc gatcgtacac
     7321 ttcacgttta tggcggataa cttcgccgtc tttgcgcgtg agatcgtaag taatgttgtg
     7381 cagggtgaaa tagttatcgg agagaatttt gtctttaatg agggtgattt gttgcgtcat
     7441 accgactcca cagcgcgaaa tgaacaatta tcttacgctg tgaagtcggg tttgtctgcg
     7501 caggctatca gtgagatttg actgatttta cccccagcca gtcaataatc ccctgtgccg
     7561 catgacgtcc ttctgccatt gcggtaacca ccagatccgc accacgcacg gcgtcaccac
     7621 cagcgaagat tttcggattg gtggtctggt aacggtactg gctttccaca tccgcgatga
     7681 tgcggcccca tttgtctacc gttacaccgt gcgactccag ccacggcatc ccgtgcggat
     7741 tgaagccaaa cgccataatc accgcgtcgg ctggcatgac aaattcactg ccttccaccg
     7801 gcactggacg ccgacgcccc tgggcatccg gctctccaag acgcgtgcgc aggaaacgaa
     7861 tcccgcagac gtgaccttgt tcattcagct caagcgccac cggctggacg ttaaattcga
     7921 agttggcccc ctcttcgcgg gcgttcttca cttctttctt cgagcctggc atgttagctt
     7981 catcacgacg ataagcgcag gtgacgttac tcgcgccgtg gcgcagtgcg gtacgcacac
     8041 agtccatcgc ggtgtcgccg ccgcccagta ccacgacgtt aagtccggcg gtattgataa
     8101 acggctcttc cggtagctct tcgagcccca tcacctgttt agtgttggca atgaggaacg
     8161 gcagcgcgtc ataaacgccc ggcgcatctt cattgggtaa acccgctttc atggaacggt
     8221 aagtgcctac gccaacgaag accgcgtcgt attgttccaa aagcgaatcc aaagagacat
     8281 ctttacccac ttcacaattg agttcgaagt gaatccccat cgcgctgaag atttcccgac
     8341 ggcgtgccag cagggattta tccagtttga aagaaggaat gccgaaagtg agcaagccac
     8401 cgatttctgg atggcgatcg tacaccgtca cccccacgcc attgcgggtc agaacatccg
     8461 cacaggccag ccctgccgga cctgcaccga taatcgccac ccgcttgtcc actttggtga
     8521 catggcttaa gtcaggacgc caacctttcg ccaacgcctg atctgaaatg tagcgttcaa
     8581 tgttgccgat agttaccgcg ccgtgctcat cgcgaatagt acaggcacct tcacacaaac
     8641 ggtcttgcgg acaaacgcgt ccggtaattt ccggcagggt gttggtctgg tgagaaagct
     8701 cgacggcggc gtcgatgttt ccggctttca ccagttcaat ccactgcggt atatggttat
     8761 gcagcgggca ggtccattca caaacgctgt gctcgccgca cttaaggcag cgcgaggctt
     8821 cccgttgtgc ctggtcggcg cgaaatggca gataaatttc atcaaaaccg gttttgcgcg
     8881 cttcaatcgc cagtttatcc ggctcgccac gcgcgggcgt tgcctgcatt tgttcgactt
     8941 tactcattac cggcatttct tgcgccgcgg tactggcatg ccacggttga tgttcctgac
     9001 gcgcggtgcg caagcggcgg aatttcgcca tgccggagag tgcgacgtca gtgaccagtt
     9061 gcagcgcgtc cgccgggcaa ttctcaacac aggcaggacc gttttcgcgc cccgcacaaa
     9121 ggtcgcattt atgcgccgtg gcttttactt ttcctgccgc gacgggtgtc aggacgattt
     9181 gcatcgtacc aaaaggacag gccaccacgc aggatttaca gccaatacac ttttgctgat
     9241 tgacctgaat gctgtcatca acgtggctga ttgcgccatt agggcagcta cgggcgcagg
     9301 gcgcatcttc acaatggtga caggtcactg cactacgttg ctgttgatgt ttgataaccg
     9361 taattcgggg atgaaaatgg tgttggctca ggacatgttg ctcatcattg tgagccatga
     9421 cacaggcgat ttcacaagca tgacaaccca gacattgctg actgttggcc ataataaaac
     9481 gattcataac gaccttcttt tttggttgta aaaaccttat tctttatatg agtgttgtta
     9541 ttacccgact tacaggggaa tcggcaatgt tcatgtgccc agaataagta actatttcgc
     9601 tataaactgt ggcagatcaa ataatcccat cactgactaa attgcgtttc agcgaactgg
     9661 aacattaatg attttttgtg gagaagacgc gtgtgattgt taaacgaccc gtctcggcca
     9721 gtctggcccg ggcctttttt tacattgtgc tgctgtcgat tctttccacg ggtatcgctc
     9781 tgctaactct ggcgagcagt ttgcgcgacg ctgaggctat caatattgcc ggatcgctgc
     9841 gtatgcagag ttaccgcctg ggctacgact tgcaaagtgg cagtccacaa ctcaatgcac
     9901 atcgccagtt atttcagcag gcactgcatt caccggtatt aaccaacctc aacgtctggt
     9961 atgtgccaga agcagtaaaa actcgctatg cgcatctgaa tgccaactgg ctggagatga
    10021 ataatcggct cagcaagggc gatttgccgt ggtatcaggc caatattaat aattatgtta
    10081 atcagataga cctgttcgta ctggctttac agcactacgc tgaacgcaaa atgctgctgg
    10141 tggtggcgat ttccctggct ggcggcatcg gtattttcac gctggtcttt tttactttgc
    10201 gccgcatacg ccatcaggtg gttgccccgc tgaatcagct ggttaccgcc agtcagcgta
    10261 ttgaacacgg gcagttcgac tcgccgccgc tggataccaa cctgccgaat gagcttggtc
    10321 tgcttgcaaa aacctttaac cagatgtcga gcgagctgca taaattgtac cgttcgctgg
    10381 aagcgtcagt agaagaaaag acccgcgatc tccacgaggc caagcgtcgt ctggaggtgt
    10441 tgtatcagtg ttcgcaggcg ctgaacacta gccagattga tgtgcattgt ttccgccata
    10501 ttttgcagat tgttcgcgac aatgaagcgg ctgaatatct ggagttaaat gtcggtgaaa
    10561 actggcggat tagcgaaggg caaccaaacc cggaattgcc gatgcagatt ttaccggtga
    10621 caatgcaaga gacggtttac ggcgaactgc actggcaaaa tagtcacgtt tcatcatcag
    10681 aaccgctgct taacagcgtt tcgtcgatgc tgggacgcgg tttgtacttt aatcaggcgc
    10741 agaagcattt tcagcaatta ttgttgatgg aagaacgtgc gaccatcgcc cgcgaattgc
    10801 acgactcgct ggctcaggta ctttcttact tacgtatcca gttgacgtta ctgaagcgtt
    10861 cgataccgga agataacgcc accgcacaaa gtatcatggc cgatttttcc caggcgttga
    10921 atgatgctta tcggcagtta cgcgagctgt tgactacttt ccgcctgacg ctgcagcagg
    10981 cggatctccc ctccgcattg agggaaatgc tggatacgtt acaaaatcaa accagcgcca
    11041 aactgaccct cgactgccgt ctgccaaccc tggcactgga tgcgcaaatg caggtgcatt
    11101 tgttgcaaat tattcgcgaa gcggtgctga atgcgatgaa gcacgccaac gccagcgaaa
    11161 tcgccgtcag ttgcgtcacc gcgccggacg gcaatcacac ggtttatatc cgtgataacg
    11221 ggattggtat cggtgaaccg aaagaacccg aaggtcatta tggtctgaat atcatgcgcg
    11281 aacgcgcgga acggctaggt gggacgctga ctttttcaca accttccggc ggcggcacgt
    11341 tagtgagtat tagctttcgc tctgcggagg gtgaggaaag tcagttaatg taatgcctcc
    11401 tactgaccaa agaatacttg cacttaaggt tcagtataaa agggcatgat aatttacatt
    11461 aactcctttt tttctccacg attggctcgt accttgccgc tacagtgaag caagtcaagc
    11521 ctacaacgat acgcagaaac acgaggtcct cttttaatgg cgaatttctt tattgatcgc
    11581 cccatttttg cctgggtgct ggcaatcctg ttgtgtctga caggtaccct ggcgattttt
    11641 tcattgcccg ttgaacaata ccccgatctc gcgccaccga atgtgcgagt gaccgctaac
    11701 tatcccggcg catcggccca gacgctggaa aacaccgtga cccaggttat cgagcaaaat
    11761 atgaccggcc tcgataatct catgtatatg tcatctcaga gcagtggcac cggtcaggca
    11821 tctgtcactt taagttttaa agcaggcacc gatccggacg aagccgtgca gcaagtacaa
    11881 aaccagctgc aatcagccat gcgaaagtta ccgcaggcgg tgcaaaatca gggcgtgacg
    11941 gtgcgtaaaa ccggcgatac caacattctg accattgcct tcgtctctac cgatggttcg
    12001 atggataaac aggatattgc tgattatgtt gccagtaata ttcaggaccc gttaagccgc
    12061 gtgaatggcg tcggggatat cgatgcctat ggttcgcaat attccatgcg tatctggctg
    12121 gacccggcga aactcaacag tttccagatg acggctaaag atgtcactga tgccattgag
    12181 tcacagaacg cgcagattgc ggttgggcaa cttggtggta caccttccgt cgataagcag
    12241 gcgctcaacg ccaccattaa cgcccagtca ctgctgcaaa caccagaaca gttccgcgat
    12301 atcaccttgc gggtcaatca ggacggctca gaggtaaggc tgggcgatgt cgccaccgtc
    12361 gaaatggggg cggagaaata cgattatctt agccgcttca atggtaagcc agcctccggg
    12421 ctgggggtaa aactggcctc cggcgctaac gaaatggcga cagcggagct ggtgctcaat
    12481 cgtctcgacg agctggcgca gtatttcccg catggactgg aatacaaggt ggcgtatgaa
    12541 accacctcgt ttgttaaagc ctccattgaa gacgtggtga aaacgctgct ggaagctatc
    12601 gctctggttt tcctcgttat gtatctgttc ctgcaaaact tccgcgccac gctgataccc
    12661 actatcgccg tgccggtggt gttgatggga accttctccg tactttacgc cttcggttac
    12721 agcgtcaaca ccttaaccat gttcgcgatg gtgctggcga tcggtctgct ggtggatgac
    12781 gccatcgtgg tggtggaaaa cgtcgaacgt attatgagtg aggaaggact cactcctcgc
    12841 gaagccacac gtaaatcgat ggggcagatc cagggggcac tggtcgggat tgcgatggtt
    12901 ctttcggcgg tatttgtacc aatggccttc ttcggcggca ccaccggtgc catctatcgc
    12961 cagttctcta ttaccattgt tgcggcgatg gtgctgtcag tactggtagc gatgatcctc
    13021 actccggctc tgtgtgccac actacttaag ccactgaaaa aaggtgagca tcatgggcaa
    13081 aaaggctttt ttgcctggtt taaccagatg tttaaccgca acgccgaacg ctacgaaaaa
    13141 ggggtggcga aaattctcca ccgtagcctg cgctggattg tgatttatgt cctgctgctt
    13201 ggcggcatgg tgttcctgtt cctgcgtttg ccgacgtcgt tcttaccgct ggaagaccgt
    13261 ggcatgttta ctacctcggt acagttgccc agcggttcaa cgcaacaaca gaccctgaaa
    13321 gtcgttgagc aaatcgagaa atactacttc acccatgaaa aagacaacat catgtcggtg
    13381 tttgccaccg ttggttctgg ccctgggggt aacgggcaaa acgtggcgcg aatgtttatc
    13441 cgcctgaaag actggagcga acgcgacagt aagaccggca cctcgtttgc cattatcgag
    13501 cgtgcaacga aggcgtttaa ccaaattaaa gaagctcgcg ttatcgccag cagcccgcca
    13561 gcaattagcg gtcttggtag ttctgcaggt tttgatatgg agttgcagga ccacgctgga
    13621 gcgggtcacg atgcgctgat ggcagcacgt aatcagttgc tggcgctggc ggcggaaaac
    13681 ccggagctaa cccgtgtgcg ccataacggc ctcgacgaca gtccgcagtt gcagattgat
    13741 atcgaccagc gtaaagctca ggcgctgggc gttgctatcg acgatattaa cgacacactg
    13801 caaaccgcct ggggttcgag ctatgtgaat gactttatgg atcgcggtcg cgtgaagaaa
    13861 gtctatgtgc aggcagctgc gccgtatcgc atgctgccag atgacatcaa tctctggtat
    13921 gtccgaaata aagatggcgg catggtgccc ttctctgctt tcgcgacctc acgctgggaa
    13981 acaggctcgc cgcgtctgga acgctataac ggttattctg cggttgagat tgttggggaa
    14041 gccgcaccgg gggtcagtac cggtacggcg atggatatta tggaatcgtt agtgaagcag
    14101 ctgccaaacg gctttggtct ggagtggacg gcgatgtcgt atcaggagcg gctttccggc
    14161 gcgcaggctc cggcgctgta cgccatttcc ttgctggtgg tattcctgtg tctggctgcg
    14221 ttgtatgaaa gctggtcggt gccgttctcg gtaatgctgg tcgtgccgct gggggtaatc
    14281 ggcgcgctgc tggcaacctg gatgcgcggg ctggaaaacg acgtttactt ccaggtgggc
    14341 ctgttaacgg tcattggttt atcggcgaaa aacgccatcc tgatcgtcga gtttgctaac
    14401 gagatgaacc aaaaaggcca cgacctgttt gaagcgacgc tccacgcctg ccgtcagcgt
    14461 ttacgcccga ttctgatgac ctcgctggca tttatcttcg gcgtattgcc aatggcaacc
    14521 agcacgggtg ccggttccgg tggtcagcat gcggtgggta ctggcgtaat gggcgggatg
    14581 atttcggcca ctattctggc tatttacttc gtgccgctgt tctttgtgct ggtgcgccgc
    14641 cgcttcccgc tgaagccgcg cccggaataa gcaataaaaa aggcgacatg ccaatgtgtc
    14701 gcctttttca actttccgat taagaacctg ctcagcgggt tcttgctgtt tgtactttgt
    14761 ctcaggaatt acttacgaag cataacttcg ataaagtctt tccagttccc cagttcacgt
    14821 tcaatcataa caacctctct tataattatg ggtattctac ggaaacaata taccgtggtg
    14881 aagctaattt actcgattgc tgcgatgact acctccgggg gacaaatctt atgtaaatac
    14941 tatggtcctg cggtgatgat ttgtatgtga tacacagcaa catttcgaga tattcatacg
    15001 gcatctaata ctgatttaat tctggttaaa ata
//
LOCUS       DAPHKZ010000109        14978 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.109, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000109 DAPHKZ010000000
VERSION     DAPHKZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14978
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.109"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            22..891
                     /locus_tag="RH288_003497"
     CDS             22..891
                     /locus_tag="RH288_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HDV4032519.1"
                     /translation="MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSVMELR
                     DLLIALESRLHQKHKLDAAARLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNT
                     LELTDNQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSL
                     LDFLPLYDVDCQENGNLEYDTYSQPEWKHNLFDHYLAVLYRFKDESGKEQFSGAVVKT
                     REATPGKEIEAITRRMLDFSPRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHL
                     RVQSTSKTAPQAK"
     gene            complement(1084..1437)
                     /locus_tag="RH288_003498"
     CDS             complement(1084..1437)
                     /locus_tag="RH288_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HDV4032520.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQ
                     LIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAAAMGGNVIYGISSPSQGMLSSFV
                     PTDSQIIGQVYKCPN"
     gene            complement(1575..3221)
                     /gene="groL"
                     /locus_tag="RH288_003499"
     CDS             complement(1575..3221)
                     /gene="groL"
                     /locus_tag="RH288_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDV4032521.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITE
                     GLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM"
     gene            complement(3265..3558)
                     /locus_tag="RH288_003500"
     CDS             complement(3265..3558)
                     /locus_tag="RH288_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDV4032522.1"
                     /translation="MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVG
                     NGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            3834..5090
                     /gene="yjeH"
                     /locus_tag="RH288_003501"
     CDS             3834..5090
                     /gene="yjeH"
                     /locus_tag="RH288_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine/branched-chain amino acid
                     transporter"
                     /protein_id="HDV4032523.1"
                     /translation="MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWA
                     WPVLIILVFPIAIVFAILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPA
                     ALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
                     AIWWAGDIKPANIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFP
                     RALMIGLLLAGLVYWGCTVVVLHFDAYGEKMAAAASLPKIVVQLFGVGALWIACVIGY
                     LACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIH
                     ALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKS
                     LYALIMLAGLWLLLPKRKTPENGITT"
     gene            complement(5106..5582)
                     /gene="fxsA"
                     /locus_tag="RH288_003502"
     CDS             complement(5106..5582)
                     /gene="fxsA"
                     /locus_tag="RH288_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418564.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HDV4032524.1"
                     /translation="MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGM
                     SLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD"
     gene            5919..7355
                     /gene="aspA"
                     /locus_tag="RH288_003503"
     CDS             5919..7355
                     /gene="aspA"
                     /locus_tag="RH288_003503"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HDV4032525.1"
                     /translation="MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
                     IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNI
                     QRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGA
                     YVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCIN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            7473..8774
                     /gene="dcuA"
                     /locus_tag="RH288_003504"
     CDS             7473..8774
                     /gene="dcuA"
                     /locus_tag="RH288_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HDV4032526.1"
                     /translation="MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGN
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE
                     IKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVI
                     CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML"
     gene            8890..9228
                     /gene="cutA"
                     /locus_tag="RH288_003505"
     CDS             8890..9228
                     /gene="cutA"
                     /locus_tag="RH288_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HDV4032527.1"
                     /translation="MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIP
                     GATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTD
                     YLSWLNASLR"
     gene            9204..10901
                     /gene="dsbD"
                     /locus_tag="RH288_003506"
     CDS             9204..10901
                     /gene="dsbD"
                     /locus_tag="RH288_003506"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HDV4032528.1"
                     /translation="MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQN
                     QHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTL
                     PVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAAPQPVSVPQQEQPT
                     AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMA
                     LTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLT
                     LMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYAL
                     GMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSA
                     LGVAFFGWAFITSLQAKRGWMRIVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNF
                     TQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQA
                     NVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP"
     gene            10938..11513
                     /locus_tag="RH288_003507"
     CDS             10938..11513
                     /locus_tag="RH288_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV4032529.1"
                     /translation="MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRLWPD
                     KEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIA
                     ACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
                     VNRSQADVDTAHRLAEDILRFARCRQGGALT"
     gene            11620..11695
                     /locus_tag="RH288_003508"
     tRNA            11620..11695
                     /locus_tag="RH288_003508"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11653..11655,aa:Phe,seq:gaa)
     gene            11893..13155
                     /locus_tag="RH288_003509"
     CDS             11893..13155
                     /locus_tag="RH288_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDV4032530.1"
                     /translation="MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRI
                     LGKEKTLALGVYPEVSLSEARTKRDEARKLISEGIDPCEQKRAKKVVPDLQLSFEHIA
                     RRWHASNKQWAQSHSDKVLKSLKTHVFPFIGNRDITTLSTPDLLIPVRAAEAKQIYEI
                     ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELLSRIGS
                     YKGQSVTRLAVMLNLLVFIRSSELRYARWSEIDIDNAMWTIPAEREPLPGVKFSHRGS
                     KMRTPHLVPLSKQAVAILAELQAWAGENGLIFTGAHDPRKPISENTVNKALRVMGYDT
                     TKDVCGHGFRTMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLML
                     QWWADFLDANREEHISPFEYAKINNPLK"
     gene            13341..13556
                     /locus_tag="RH288_003510"
                     /pseudo
     CDS             13341..13556
                     /locus_tag="RH288_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13666..14043)
                     /locus_tag="RH288_003511"
     CDS             complement(13666..14043)
                     /locus_tag="RH288_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HDV4032531.1"
                     /translation="MRHISPEELIAIHDANISRYGGLPGMSDSGRAEAIIGRVQARVA
                     YEEITGLFEVSATYLVATARGHIFNDANKRTALNSALLFLRRNGVQVYDSPELAELTV
                     GAATGEVSVSTVVATLRRLYGTA"
     gene            complement(14043..14264)
                     /locus_tag="RH288_003512"
     CDS             complement(14043..14264)
                     /locus_tag="RH288_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001603498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDV4032532.1"
                     /translation="MQSINFRTARSNLTEVLNNVEAGEEVEITRRGREPAVIVSKATF
                     EAYKKAALDAEFASLFDTLDTTNKKLVNR"
     gene            complement(14449..>14978)
                     /locus_tag="RH288_003513"
     CDS             complement(14449..>14978)
                     /locus_tag="RH288_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4032533.1"
                     /translation="SNIFSWILCNLLGLLNKGDAYEQKLTITVKHKPTTCRFSQPTYE
                     IRIPETTISEMLSANNSKSGSVDLVLNCDSVYNVTTNPVTFKVERGVWDDSGTILKNT
                     LSDGAKGVGFQIYNGNATTPLKLGDTLMNRLPKMAAIQEQYIFPITAKYVRVKEEALQ
                     PGEVQGQAIFAVSYD"
BASE COUNT         3661 a         3856 c         3637 g         3824 t
ORIGIN      
        1 aaatggttag ggagaaccta catggccata agcatcaagg gtgttaatac cggtgttatt
       61 cgcaagagta ataatttcat tgcactggcg ctgaaaatta aagaacctcg caataaagaa
      121 tcgttgttct ttatgtctgt catggaactg cgcgacctgc tgattgcgct ggaaagtcgt
      181 ctgcatcaaa agcataaact ggatgctgct gcacgccttc agtatgagca agctcgcgat
      241 aaagtcatta agaaaatggc agaaaacatc ccagaaattc tggttgatga gcttaaaaat
      301 gccgatatta atcgtcgggt taacacgctg gaacttaccg ataatcaagg cgaaaatctt
      361 accttcgtat taacgctaca tgacggtagc aaatgtgagt tagtcgtcaa tgagttgcag
      421 attgaaatgc tggcgcgagc aatcattcat gcaattaata atgcggaaat gcgtgaactg
      481 gcattacgta ttacctcact gttagatttc ctgccgttat atgacgttga ctgccaggaa
      541 aatggcaatc tggaatatga cacctattcc caaccggaat ggaaacataa cttgttcgac
      601 cattatctgg cggtgcttta ccgctttaaa gatgaaagtg gcaaagaaca atttagcggc
      661 gcagtggtga aaacgcgtga agcaacgccg ggtaaagaaa tagaggcgat cactcgccga
      721 atgcttgatt tcagcccacg actgaaaaaa ctcgcgggtg tgccatgtca ggtctatgtt
      781 cgcaccgtag cggcgaataa cgcccaaccg ctaacccagg atcaatgctt acgcgcgctg
      841 catcacttac gtgttcaatc caccagcaaa actgcaccac aggcgaaata atctcatctt
      901 tgctaatgcg aggctggagc catccagcct gaaatgactg ataacgtgat cgttggtcat
      961 gccggatgcg gcgtaaacgc cttatccggc ctacaaattc tcaagcattc aatcagttgc
     1021 aatgccttat gtaggcctga taagcgaagc gcctctggca attatacgtt tgtcaccatc
     1081 acatcagttc gggcacttat aaacctgacc gataatctgg ctatccgtcg ggacaaaact
     1141 ggacaacatt ccctgcgacg ggctgctgat gccataaatc acgttaccgc ccattgcagc
     1201 cgcctggttg cgcagatcgt ttgctgcgcc gcgcatagaa ccgccctctt ctccgtgttg
     1261 cccggaaagc cagttgcttt gcttacctgt cgcagtacca atcagctggc actctgcgcc
     1321 tggctgctcg tccacaatgc gtacactctg accggcagca ctcaattcgt tgctggagct
     1381 acaacccgcc atcagtagcg cggcaccgac aatccctgct aagtatttta cgtgcatgtt
     1441 attccccata atcaatgagc tggacgccac tcgcgtcgtc cgtgtctgaa tcttatacta
     1501 gaaagatgac caaaagaaaa acccccagac atttctgccc gggggtttgt ttatttctgc
     1561 gaggtgcagg gcaattacat catgccgccc atgccaccca tgccgcccat accgccagca
     1621 gcgcctaagt cagctgcatc atttttcggc aggtcggtaa ccatgcactc ggtggtgatc
     1681 atcaagccag ccacagaagc cgcgtactgc agagcagaac gggttacttt ggttgggtcc
     1741 aggataccca tgtcgatcat gttgccgtat tcttcggttg ctgcgttgta accgtagttg
     1801 ccgtcgccgc ctttaacggt gttagcaaca acagacggtt cttcgccgca gttcaggacg
     1861 atctgacgca gcggagcttc cattgcacgc agtgcaactt tgatacccac gttctggtct
     1921 tcgttctgac cacgcaggtc agccagttta gacgctacgc ggatcagcgc aacaccacca
     1981 ccagcaacca cgccttcttc taccgcagca cgggtcgcgt gcagggcgtc ttcaacgcgt
     2041 gcttttttct ctttcatttc aacttcggta gcagcaccta ctttgataac tgcaacgccg
     2101 cctgccagtt tcgctacgcg ttcctgcagt ttttcacggt cgtagtcaga agttgcttct
     2161 tcaatctgct gacggatctg agcaacacgg ccctggattg cagcttcttc acccacgcca
     2221 tcgatgatag tggtggtgtc tttgttgatc acaacacgtt tagcctgacc caggtcttcc
     2281 agggttgctt tttccagttc cataccgatc tcttcagaga tcacggtacc gccagtcagg
     2341 gttgcgatat cctgcagcat agctttacga cgatcgccga agcccggagc tttaactgca
     2401 gcaactttca cgatgccacg catggtgtta acaaccagag ttgccagcgc ttcgccttct
     2461 acatcttcag cgatgatcag cagcggtttg cctgctttgg caacggcttc cagaaccggc
     2521 agcatttcgc ggatgttgga gattttcttg tcagccagca ggatgaacgg gctttccagt
     2581 tctactgcgc cagtttccgg cttgttgatg aagtaaggag acaggtagcc acggtcgaac
     2641 tgcatacctt caaccacgtc cagttcgtcc tgcagaccgg taccgtcttc aacggtgata
     2701 acgccttctt taccgacttt gtccatcgct tcagcgatca gtttacctac ggtttcgtcg
     2761 gagttagcgg agatggtacc aacctgagca atcgctttag agtcagagca cggtacggac
     2821 agcgctttca gttcttcaac tgcagcggta acggctttgt cgataccacg tttcaggtcc
     2881 atcgggttca tgcccgcagc aacagctttc agaccctcag tgatgatagc ctgagccagt
     2941 acagttgcag tggtggtacc gtcgcctgca gcgtcgttcg ctttagaggc aacttctttc
     3001 accatctgcg cacccatgtt ttcgaacttg tcttccagtt cgatttcacg agcaacggaa
     3061 acaccatctt tggtgatggt cggtgcaccg aaagatttat ccagaactac gttacggcct
     3121 ttcggaccga gggtaacttt cactgcatct gccagtacgt ttacgccgcg cagcattttc
     3181 acacgagcgt cgttaccgaa ttttacgtct ttagctgcca ttatctttat tccttaaatt
     3241 cgtatgttca gtgtcgtgcg aggattacgc ttcaacaatt gccagaatgt cgctttcgga
     3301 catgatcaac acttcttcat tgtcgatctt ctcagatttc acaccgtagc catcgttgaa
     3361 aataacgatg tcgccaactt tcacatccag cggcttcact tcgccatttt caaggatacg
     3421 gccattgccg acagccagca cttcgccgcg ggtggattta gccgctgcag agccggtcag
     3481 aacgatgccg ccagcagatt tagtttcaac ttctttacgc ttgacgatca cgcgatcatg
     3541 caatggacga atattcattg ataactctcc tttgagaaag tccgtatctg ttatgggtga
     3601 cgccggagct tacgtggttt cccggctggt gaccagagaa atggggatga ggcttcgccc
     3661 cttcaagggg gaaaaagaaa aaaaattctg atcagcacaa aatcgggtga aaaccctgat
     3721 tcacctcaca tttcatcgca atttcttcat cgccgtcata agcgaatctg attgtgctac
     3781 catcgaaaat ctacgcagtt gcccaaaatt tgggcgcaat cggacatcaa cccatgagtg
     3841 gactcaaaca agaactgggg ctggcccagg gcattggcct gctatcgacg tcattattag
     3901 gcactggcgt gtttgccgtt cctgcgttag ctgcgctggt agcgggcaat aacagcctgt
     3961 gggcgtggcc cgttttgatt atcttagtgt tcccgattgc gattgtgttt gcgattctgg
     4021 gtcgccacta tcccagcgca ggcggcgtcg cgcacttcgt cggtatggcg tttggttcgc
     4081 ggcttgagcg agtcaccggc tggctgtttt tatcggtcat tcccgtgggt ttgcctgccg
     4141 cactacaaat tgccgccggg ttcggccagg cgatgtttgg ctggcatagc tggcaactgt
     4201 tgttggcaga actcggtacg ctggcgctgg tgtggtatat cggtactcgc ggtgccagtt
     4261 ccagtgctaa tctacaaacc gttattgccg gacttatcgt cgcgctgatt gtcgctatct
     4321 ggtgggcggg cgatatcaaa cctgcgaata tcccctttcc ggcacctggt aatatcgaac
     4381 ttaccgggtt atttgctgcg ttatcagtga tgttctggtg ttttgtcggt ctggaggcat
     4441 ttgcccatct cgcctcggaa tttaaaaatc cagagcgtga ttttcctcgt gctttgatga
     4501 ttggtctgct gctggcagga ttagtctact ggggctgtac ggtagtcgtc ttacacttcg
     4561 acgcctatgg tgaaaaaatg gcggcggcag catcgcttcc aaaaattgta gtgcagttgt
     4621 tcggtgtagg agcgttatgg attgcctgcg tgattggcta tctggcctgc tttgccagtc
     4681 tcaacattta tatacagagc ttcgcccgcc tggtctggtc gcaggcgcaa cataatcctg
     4741 accactacct ggcacgcctc tcttctcgcc atatcccgaa taatgccctc aatgcggtgc
     4801 tcggctgctg tgtggtgagc actttggtga ttcatgcttt agagatcaat ctggacgctc
     4861 ttattattta tgccaatggc atctttatta tgatttatct gttatgcatg ctggcaggct
     4921 gtaaattatt gcaaggacgt tatcgactac tggcggtggt tggcgggctg ttatgcgttc
     4981 tgttactggc aatggtcggc tggaaaagtc tctatgcgct gatcatgctg gcggggttat
     5041 ggctgttgct gccaaaacga aaaacgccgg aaaatggcat aaccacataa tccggcgttt
     5101 cgacattaat cctggcgatc gtctttatga tcaaggcggt cgcgctcatc atcctttcgc
     5161 tggtactcac catcaaaagt attaccgcca ccggtcccgg cgctaaaacc gccgccaggc
     5221 atgcgagaaa agcgcaaatg cggcatcaac ttcactgtca gatgcttttg caccggcggc
     5281 aataaaagta gaagaccgag gaagtcggta aaaaagcccg gtaataaaag cagcaaacca
     5341 gcaatgatca gcgaaacact tttaatcatc tccgccgctg ggttttcacc cgccgccatt
     5401 ttttgctgca tcagcacgaa attcttaaag ccctggttac gtaccagtga cataccgata
     5461 actgacgtga atataaccag cacgagggtc agcaataccc ccaatacatg ggcaacctga
     5521 ataaagattg aaatctcaat atagacataa aggaaaatgg caataaaagg taaccagcgc
     5581 aaaggtttct cctgtaatag cagccggtta accccggcta cctgaatggg ttgcgaatcg
     5641 cgtttagctt atattgtggt cattagcaaa atttcaagat gtttgcgcaa ctatttttgg
     5701 tagtaatccc aaagcggtga tctatttcac aaattaataa ttaaggggta aaaaccgaca
     5761 cttaaagtga tccagattac ggtagaaatc ctcaagcagc atatgatctc gggtattcgg
     5821 tcgatgcagg ggataatcgt cggtcgaaaa acattcgaaa ccacatatat tctgtgtgtt
     5881 taaagcaaat cattggcagc ttgaaaaaga aggttcacat gtcaaacaac attcgtatcg
     5941 aagaagatct gttgggtacc agggaagttc cagctgatgc ctactatggt gttcacactc
     6001 tgagagcgat tgaaaacttc tatatcagca acaacaaaat cagtgatatt cctgaatttg
     6061 ttcgcggtat ggtaatggtt aaaaaagccg cagctatggc aaacaaagag ctgcaaacca
     6121 ttcctaaaag tgtagcgaat gccatcattg ccgcatgtga tgaagtcctg aacaacggaa
     6181 aatgcatgga tcagttcccg gtagacgtct accagggcgg cgcaggtact tccgtaaaca
     6241 tgaacaccaa cgaagtgctg gccaatatcg gtctggaact gatgggtcac caaaaaggtg
     6301 aatatcagta cctgaacccg aacgaccatg ttaacaaatg tcagtccact aacgacgcct
     6361 acccgaccgg tttccgtatc gcagtttact cttccctgat taagctggta gatgcgatta
     6421 accaactgcg tgaaggcttt gaacgtaaag ctgtcgaatt ccaggacatc ctgaaaatgg
     6481 gtcgtaccca gctgcaggac gcagtaccga tgaccctcgg tcaggaattc cgcgctttca
     6541 gcatcctgct gaaagaagaa gtgaaaaaca tccaacgtac cgctgaactg ctgctggaag
     6601 ttaaccttgg tgcaacagca atcggtactg gtctgaacac gccgaaagag tactctccgc
     6661 tggcagtgaa aaaactggct gaagttactg gcttcccatg cgtaccggct gaagacctga
     6721 tcgaagcgac ctctgactgc ggcgcttatg ttatggttca cggcgcgctg aaacgcctgg
     6781 ctgtgaagat gtccaaaatc tgtaacgacc tgcgcttgct ctcttcaggc ccacgtgccg
     6841 gcctgaacga gatcaacctg ccggaactgc aggcgggctc ttccatcatg ccagctaaag
     6901 taaacccggt tgttccggaa gtggttaacc aggtatgctt caaagtcatc ggtaacgaca
     6961 ccactgttac catggcagca gaagcaggtc agctgcagtt gaacgttatg gagccggtca
     7021 ttggccaggc catgttcgaa tccgttcaca ttctgaccaa cgcttgctac aacctgctgg
     7081 aaaaatgcat taacggcatc actgctaaca aagaagtgtg cgaaggttac gtttacaact
     7141 ctatcggtat cgttacttac ctgaacccgt tcatcggtca ccacaacggt gacatcgtgg
     7201 gtaaaatctg tgccgaaacc ggtaagagtg tacgtgaagt cgttctggaa cgcggtctgt
     7261 tgactgaagc ggaacttgac gatattttct ccgtacagaa tctgatgcac ccggcttaca
     7321 aagcaaaacg ctatactgat gaaagcgaac agtaatcgta cagggtagta caaataaaaa
     7381 aggcacgtca gatgacgtgc cttttttctt gtgagcagta acttaaaaat aacaatctaa
     7441 tatcaacttg ttaaaaaaca aggaaggcta atatgctagt tgtagaactc atcatagttt
     7501 tgctggcgat cttcttgggc gccagattgg ggggaatagg tattggtttt gcaggcggat
     7561 tgggggtgct ggttcttgcc gctattggcg ttaaacccgg taacatcccg ttcgatgtca
     7621 tctccattat catggcggtt atcgccgcta tttctgccat gcaggttgct ggcggtctgg
     7681 actatctggt tcatcagaca gaaaagctgc tgcgccgtaa cccgaaatac atcacgatcc
     7741 tcgcaccgat cgtgacctat ttcctgacta tctttgctgg tactggcaac atctctctgg
     7801 cgacactgcc agttatcgct gaagttgcga aggaacaagg cgttaaacct tgccgtccgc
     7861 tgtctactgc agtggtatcc gcgcagattg cgatcaccgc atcgccaatc tcagcggcag
     7921 tggtttacat gtcttccgtg atggaaggtc atggcatcag ctacctccat ctgctctccg
     7981 tggtcatccc gtccaccctg ctggcggttc tggtgatgtc cttcctggtc actatgctgt
     8041 tcaactccaa actctctgac gatccgattt atcgcaagcg tctggaagag ggcctggttg
     8101 aactgcgcgg tgaaaagcag attgaaatca aatccggtgc aaaaacgtcc gtctggctgt
     8161 tcctgctggg cgtagttggc gtggttatct atgcaatcat caacagccca agcatgggtc
     8221 tggttgaaaa accgctgatg aacaccacca acgcaatcct gatcatcatg ctcagcgttg
     8281 caactctgac caccgttatc tgtaaagtcg ataccgacaa catcctcaac tccagcacct
     8341 tcaaagcagg tatgagcgcc tgtatttgta tcctgggtgt tgcgtggctg ggcgatactt
     8401 tcgtttccaa caacatcgac tggatcaaag ataccgctgg tgaagtgatt cagggtcatc
     8461 cgtggctgct ggccgtcatc ttcttctttg cttctgctct gctgtactct caggctgcaa
     8521 ccgcaaaagc actgatgccg atggctctgg cactgaacgt ttcaccgctg accgctgttg
     8581 cttctttcgc tgcggtgtct ggtctgttca ttctgccgac ctacccgacg ctggttgctg
     8641 cggtacagat ggatgacacg ggtactaccc gtatcggtaa attcgtcttc aaccatccgt
     8701 tcttcatccc gggtactctg ggtgttgccc tggccgtttg cttcggcttc gtgctgggta
     8761 gcttcatgct gtaatgatca atcgcggggc gttcacgccc cgctttcttt cccgccgact
     8821 aacatccttc ccccgtccgt tgtatagtga cctctctctt gcggttccat ctgttcttgc
     8881 gaggtgttta tgcttgatga aaaaagttcg aataccgcgt ctgtcgtggt gctatgtacg
     8941 gcaccagatg aagcgacagc ccaggattta gccgccaaag tgctggcgga aaaactggcg
     9001 gcctgcgcga ccttgatccc cggcgctacc tctctctatt actgggaagg taagctggag
     9061 caagaatacg aagtgcagat gattttaaaa actaccgtat ctcaccagca ggcactgctg
     9121 gaatgcctga agtctcatca tccatatcaa accccggaac ttctggtttt acctgttaca
     9181 cacggagaca cagattacct ctcatggctc aacgcatctt tacgctgatc ctgctacttt
     9241 gcagcacttc cgtttttgcc ggattattcg acgcgccggg acgttcacaa tttgtccccg
     9301 cggatcaagc ctttgctttt gattttcagc aaaaccaaca tgaccttaat ctgacctggc
     9361 agatcaaaga cggttactac ctctaccgta aacagatccg cattacgccg gaacacgcga
     9421 aaattgccga cgtgcagctg ccgcaaggcg tctggcatga agatgagttt tacggcaaaa
     9481 gcgagattta ccgcgatcgg ctgacgcttc ccgtcaccat caaccaggcg agtgcgggag
     9541 cgacgttaac tgtcacctac cagggctgtg ctgatgccgg tttctgttat ccgccagaaa
     9601 ccaaaaccgt tccgttaagc gaagtggtcg ccaacaacgc agcgccacag cctgtgtctg
     9661 ttccgcagca agagcagccc accgcgcaat tgcccttttc cgcgctctgg gcgttgttga
     9721 tcggtattgg tatcgccttt acgccatgcg tgctgccaat gtacccactg atttctggca
     9781 tcgtgctggg tggtaaacag cggctctcca ctgccagagc attgttgctg acctttattt
     9841 atgtgcaggg gatggcgttg acctacacgg cgctgggtct ggtggttgcc gccgcagggt
     9901 tacagttcca ggcggcgcta cagcacccat acgtgctcat tggcctcgcc atcgtcttta
     9961 ccttgctggc gatgtcaatg tttggcttgt ttaccctgca actcccctct tcgctgcaaa
    10021 cacgtctcac gttgatgagc aatcgccaac agggcggctc acctggcggt gtgtttgtta
    10081 tgggggcgat tgccggactg atctgttcac catgcaccac cgcaccgctt agcgcgattc
    10141 tgctgtatat cgcccaaagc gggaacatgt ggctgggcgg cggcacgctt tatctctatg
    10201 cgttgggcat gggcctgccg ctgatgctaa ttaccgtctt tggtaaccgc ttgctgccga
    10261 aaagcggccc gtggatggaa caagtcaaaa ccgcgtttgg ttttgtgatc ctcgcactgc
    10321 cggtcttcct gctggagcga gtgattggtg atgtatgggg attacgcttg tggtcggcgc
    10381 tgggtgtcgc attctttggc tgggccttta tcaccagcct acaggctaaa cgcggctgga
    10441 tgcgtattgt gcaaattatt ctgctggcag cggcattggt tagcgtgcgc ccacttcagg
    10501 attgggcatt tggtgcgacg cataccgcgc aaactcagac gcatctcaac tttacacaaa
    10561 tcaaaacggt agatgagtta aatcaggcgc tcgttgaagc caaaggcaaa ccggtgatgt
    10621 tagatcttta tgccgactgg tgcgtcgcct gtaaagagtt tgagaaatac accttcagcg
    10681 acccgcaggt gcaaaaagcg ttagcagaca cggtcttact tcaggccaac gtcacggcca
    10741 acgacgcaca agatgtggcg ctgttaaagc atcttaatgt ccttggccta ccgacaattc
    10801 tcttttttga cggacaaggc caggagcatc cacaagcacg cgtcacgggc tttatggatg
    10861 ctgaaacctt cagcgcacat ttgcgcgatc gccaaccgtg aacgacactt gcagtgggaa
    10921 agacggagga aaatagcgtg caacgtgaag atgtactggg agaagccctg aaattattag
    10981 aattacaagg gattgccaac accacgctgg agatggttgc tgaacgtgtg gattatccac
    11041 tggacgagct acgccgctta tggccagaca aagaggcaat cctctacgat gcgctgcgtt
    11101 atcttagcca acagatagat gtctggcgtc gtcagctgat gctggacgaa acgcaaaccg
    11161 ccgaacaaaa gctgctggca cgttatcagg cgttatcgga gtgcgttaaa aacaaccgct
    11221 atccgggctg tctatttatc gctgcctgta cgttttatcc cgatcctggc caccctattc
    11281 atcaactggc cgatcagcaa aaaagcgcgg cctacgattt cacccacgaa ctgttaacca
    11341 cactggaagt tgacgatccg gcgatggtag caaagcagat ggaactggtg ctggaaggct
    11401 gtttaagccg aatgctggtg aatcgtagcc aggcggatgt cgacactgca catcggctgg
    11461 cggaagatat cctgcgcttc gcccgctgcc gccagggtgg tgcattgacc tgacagaaac
    11521 acagaaaaga agcgatttgc cgcaatctta agcagttgaa tcgcttttac tgaaattagg
    11581 ttgacgagat gtgcagatta cggtttaatg cgccccgttg cccggatagc tcagtcggta
    11641 gagcagggga ttgaaaatcc ccgtgtcctt ggttcgattc cgagtccggg caccaaattc
    11701 atatcaacgg gcctccacgg aggtccgttt ttcgtttcag aacgccacaa tttaagcgtt
    11761 ctgcctccaa atcaattcta ccgaactcaa ccagattccc cccacatcaa cctcattgtg
    11821 tgggtataat tgcgggtata ccccggttcg acagaatttg taccctcttt aacgcattca
    11881 gaaggctgta ctatggcact gactgacgca aaaatccggg ctgcaaagcc cactgacaag
    11941 gcttataaac tcactgacgg ggctggcatg ttcctgctgg ttcatcctaa tggttcccgt
    12001 tactggcgtc tccgttatcg tattctgggt aaggagaaga ctctggcact tggtgtgtat
    12061 ccggaagttt ctctctccga agctcgtaca aaacgggatg aggcccgaaa actgatttcg
    12121 gaggggattg acccttgcga acagaaaaga gctaaaaaag tagtccctga tttacaactc
    12181 tcttttgaac atattgcacg acgctggcat gccagtaata aacaatgggc acaatcacac
    12241 agcgataaag tactcaaaag cctcaagaca cacgttttcc cctttattgg caaccgggat
    12301 atcacaacac tcagtacccc ggacctgctt atccctgttc gcgccgcaga agccaaacaa
    12361 atttatgaaa tcgccagtcg tctgcagcaa aggatatccg ctgtaatgcg ttatgccgta
    12421 cagtctggca tcatcagata taatcctgct ctggatatgg ctggcgcatt gaccacggta
    12481 aaacgccagc atcgccccgc tcttgacctt tcacgcctgc ctgaacttct gtcgcgtatt
    12541 ggcagttata aggggcagtc tgtcacccgg cttgccgtta tgttgaatct gctggtgttt
    12601 attcgctcca gtgaactcag atatgcccgc tggtcagaaa ttgatattga caatgccatg
    12661 tggactattc cagccgaacg cgaacctctg cctggcgtaa aattctcaca ccggggctcc
    12721 aagatgcgaa caccacatct tgttcctctc agcaaacagg ctgtagccat actggcagaa
    12781 cttcaggcat gggcaggcga aaatggtctg atctttacgg gagcacatga cccgcgtaaa
    12841 ccaatcagtg aaaacaccgt aaataaagcc ctgagggtaa tggggtatga cacaaccaag
    12901 gacgtctgtg gtcatggatt ccggactatg gcatgcagtg cgctgattga atcaggtttg
    12961 tggtcccgcg atgctgttga aaggcagatg agtcatcagg agcgtaacgg agtacgagca
    13021 gcttatatcc ataaagccga acacctggaa gaacgccgac tgatgctaca gtggtgggcg
    13081 gattttctgg atgcaaatcg agaagagcac atcagcccct ttgagtatgc aaagattaac
    13141 aatccattaa aatagtaagc actccgggca gattgcccgg agtgctgtga atgaccattt
    13201 tctttggtaa tgctgacgaa agttgatggt aaggcaaatt atccccgccc ctcattaaca
    13261 cttatgtatg aggtggcaca ctgaatttgg ccacctgaac agaggtgata tgctcacctc
    13321 agaacaacac aggtgctcca atgaaaaaaa gaaagttcag cgcagagttt aaacgcgaat
    13381 ccactcaact ggttgttgac cagaactaca cggtggcaga tgccgccaaa gctatggatg
    13441 tcggcctttc cacaatggca agatgggtca aactgctgcg tgatgagctt cgggacaaaa
    13501 caccaaaagc ctctccgatg acaccagaac aaatcgaaat acgtgagctg aggaaaaatt
    13561 ttcttactca ccaggtattg cttaaccttg cggctgctca ccccatcaag aagcatcttt
    13621 aacgcgtcac gggacaattt gttgtatttg cgtaccatta atttactacg ccgtaccata
    13681 caatctacgt aacgtggcaa cgacagtaga tacggatacc tctccggtcg cagcccccac
    13741 agtaagctct gccagttctg gtgaatcata tacctgcaca ccgttacggc gcagaaataa
    13801 caacgcactg tttagcgcgg tacgcttatt ggcatcattg aatatatgcc ctctcgcagt
    13861 agccaccagg taagttgcgg agacttcgaa aaggccggta atctcttcat atgcaactct
    13921 ggcctggact ctcccgataa tagcctcagc tcttcccgaa tctgacatgc ctggcaggcc
    13981 gccgtagcgg cttatattcg catcatgaat tgcaataagc tcttccggtg atatatgcct
    14041 cattatcggt taaccagttt cttattggtg gtgtccagag tgtcaaacag ggatgcgaat
    14101 tcagcatcca gcgccgcttt tttgtaggct tcgaaagtgg ccttgctgac aattacagct
    14161 ggctcacgac ctctacgggt gatttcaacc tcttctccgg cttcaacatt gttgagcact
    14221 tcggtaagat tgctgcgtgc ggtacggaag ttaatagatt gcataaacac ctcatgtact
    14281 caatatgtgt acacaattat agagcttaat tgcccactac tccatcattt tatccagtgc
    14341 gccttatacc tccactctga aggacggggt tttagggcgc tctggataaa aacacacgta
    14401 ctttctctcc gaaagtacgt gaaaagtagc gactaaccac catgctcatt agtcgtagga
    14461 tacggcaaat atcgcctggc cttgaacttc cccaggctgt aaagcttcct ctttcacgcg
    14521 aacgtatttt gcggtaatcg ggaagatgta ctgctcctga atagccgcca ttttaggtaa
    14581 tctgttcatc agggtatcgc ccagctttaa cggtgtcgtt gcattaccat tgtaaatctg
    14641 gaaccctaca cccttagcac catcggacaa tgtatttttc aatattgttc cactatcatc
    14701 ccacacacca cgctcaactt taaaagtcac tggattagtc gtgacgttat agacactatc
    14761 gcaatttagg accagatcta cagaacctga ttttgagtta ttggcagata gcatctcact
    14821 tatcgttgtt tctggtattc ttatttcgta agtcggttgc gagaaacgac aggttgtggg
    14881 tttgtgttta acagtaatgg ttagtttttg ttcgtaagca tcgcctttat ttaacaaccc
    14941 caataaattg cacaatatcc atgaaaaaat atttgaac
//
LOCUS       DAPHKZ010000110        14925 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.110, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000110 DAPHKZ010000000
VERSION     DAPHKZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14925
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.110"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..156)
                     /locus_tag="RH288_003514"
     CDS             complement(<1..156)
                     /locus_tag="RH288_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HDV4032534.1"
                     /translation="MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLL
                     RLGLAYGP"
     gene            complement(233..385)
                     /gene="hokE"
                     /locus_tag="RH288_003515"
     CDS             complement(233..385)
                     /gene="hokE"
                     /locus_tag="RH288_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HDV4032535.1"
                     /translation="MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            838..1956
                     /locus_tag="RH288_003516"
     CDS             838..1956
                     /locus_tag="RH288_003516"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HDV4032536.1"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNK
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAATDHHLEICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKD
                     YLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEAL
                     HRQVASGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD"
     gene            2022..2270
                     /locus_tag="RH288_003517"
     CDS             2022..2270
                     /locus_tag="RH288_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 domain-containing protein"
                     /protein_id="HDV4032537.1"
                     /translation="MKHPLETLTTAAGILLMAFLSCLLLPAPALGLTLAQKLVTTFHL
                     MDLSQLYTLLFCLWFLVLGAIEYFVLRFIWRRWFSLAD"
     gene            2335..2703
                     /locus_tag="RH288_003518"
     CDS             2335..2703
                     /locus_tag="RH288_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDV4032538.1"
                     /translation="MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSS
                     ELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKKHWISVYPGEEISEALLRDLIND
                     SWNLVVDGLAKRDQKRVRPG"
     gene            2797..3450
                     /gene="nfsB"
                     /locus_tag="RH288_003519"
     CDS             2797..3450
                     /gene="nfsB"
                     /locus_tag="RH288_003519"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HDV4032539.1"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDAWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     gene            3558..4805
                     /gene="ybdG"
                     /locus_tag="RH288_003520"
     CDS             3558..4805
                     /gene="ybdG"
                     /locus_tag="RH288_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel YbdG"
                     /protein_id="HDV4032540.1"
                     /translation="MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     gene            complement(4873..6249)
                     /gene="pheP"
                     /locus_tag="RH288_003521"
     CDS             complement(4873..6249)
                     /gene="pheP"
                     /locus_tag="RH288_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HDV4032541.1"
                     /translation="MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFV
                     AFKTLRRK"
     gene            complement(6351..9494)
                     /gene="cusA"
                     /locus_tag="RH288_003522"
     CDS             complement(6351..9494)
                     /gene="cusA"
                     /locus_tag="RH288_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter permease
                     subunit CusA"
                     /protein_id="HDV4032542.1"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQIGPEMRRGIA
                     ELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRA
                     IDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMS
                     LGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPAL
                     FISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGK
                     IPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQIN
                     EGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMV
                     ETTIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIG
                     IKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTV
                     ADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITL
                     ADVADIKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSV
                     AFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWL
                     LWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAVPSLNNPQTFSEQKLDEA
                     LYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI
                     IPAAYKLMWLHRHRVRK"
     gene            complement(9506..10729)
                     /gene="cusB"
                     /locus_tag="RH288_003523"
     CDS             complement(9506..10729)
                     /gene="cusB"
                     /locus_tag="RH288_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     adaptor subunit CusB"
                     /protein_id="HDV4032543.1"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWVAKAEPPAEKTSTAERKILF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
                     AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQALID
                     TGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAH"
     gene            complement(10745..11077)
                     /gene="cusF"
                     /locus_tag="RH288_003524"
     CDS             complement(10745..11077)
                     /gene="cusF"
                     /locus_tag="RH288_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     metallochaperone CusF"
                     /protein_id="HDV4032544.1"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVV
                     KGIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     gene            complement(11235..12608)
                     /gene="cusC"
                     /locus_tag="RH288_003525"
     CDS             complement(11235..12608)
                     /gene="cusC"
                     /locus_tag="RH288_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter outer
                     membrane channel CusC"
                     /protein_id="HDV4032545.1"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALVNNRDLRMATLKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISL
                     YTALGGG"
     gene            12765..13448
                     /gene="cusR"
                     /locus_tag="RH288_003526"
     CDS             12765..13448
                     /gene="cusR"
                     /locus_tag="RH288_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper response regulator transcription factor
                     CusR"
                     /protein_id="HDV4032546.1"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     gene            13438..14886
                     /gene="cusS"
                     /locus_tag="RH288_003527"
     CDS             13438..14886
                     /gene="cusS"
                     /locus_tag="RH288_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) sensor histidine kinase CusS"
                     /protein_id="HDV4032547.1"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSQGKTVYHSP
                     GAPDIREFTRDAIPDKDAQGGEVYLLSGPTMMMPGHGHGHMEHSNWRMINLPVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELRFVGDKCQVAGDPLMLRRALSNLLSNALRYTP
                     PSEAIVVRCQTVNHQVQVSVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSDARGTRFVIMLPERE"
BASE COUNT         3590 a         4034 c         3698 g         3603 t
ORIGIN      
        1 ggggccgtaa gccagcccca gacgtagcag agttgcagca tcacgaattt cgcggcggcg
       61 ggttagagcc ccggcattac gtgccgaagt atccagttct tcgggcttac caatatgggc
      121 cagaattgct gaccagttat cgtgagagta attcatcggc acgttaaatc atatcaggcg
      181 taataccaca acccttaagt tagcgcttat gggattactc cccgcacaac ggctacttct
      241 tcggttcgta agcgagaaca gccttaaact caatattacg ttccttcacc gtaaactcac
      301 acagcgagtc tccgaccaga agcgtaaatc ccagcaccgt taaacacagc actatgactg
      361 ccgcaagggc atatttcgtc agcatgttta tattgcctcc atgcgaagaa gggactacca
      421 tccaaattgt tcgggtttgg agtggcagcc ccagggttga tagaaatatc tcctggggct
      481 tcatctttcc agacctcaga gtaaacctga aaccggaaag cttcaggcac ccgccgttat
      541 cttacccttc ctcaacaaaa tagctgttta tttatacagt gagtcctgtt tcggacttct
      601 cactcctcat ttaatcaact gaagctgaac ccgttttttt ctgcatgact caatcgtcaa
      661 aattcttcgc caccagtcag cactgccata acttgtcaca ttgcaaaagt agccaaattg
      721 cttcaggcac catcagttca ccatcaccaa aaaaaagaaa cattccagaa cttccgcatc
      781 tcgcccagcc gctccgactt ctatactgaa tagaaaacgc caacataaga gaaacctatg
      841 ccattacccg attttcatgt ttctgaacct tttaccctcg gtattgaact ggaaatgcag
      901 gtggttaatc cgccgggcta tgacttaagc caggactctt caatgctgat tgacgcggtt
      961 aaaaataaga tcacggccgg agaggtaaag cacgatatca ccgaaagtat gctggagctg
     1021 gcgacggatg tttgccgtga tatcaaccag gctgccgggc agttttcagc gatgcagaaa
     1081 gtcgtattgc aggcagccac agaccatcat ctggaaattt gcggcggtgg cacgcacccg
     1141 tttcagaaat ggcagcgtca ggaggtatgc gataacgaac gctatcaacg cacgctggaa
     1201 aactttggtt atctcattca gcaggcgacc gtttttggtc agcatgtcca tgttggctgc
     1261 gccagtggcg atgacgccat ttatttgctg cacggcttgt cacgatttgt gccgcacttt
     1321 atcgcccttt ccgccgcgtc gccatatatg cagggaacgg atacgcgttt tgcctcctca
     1381 cgaccgaata ttttttccgc ctttcctgat aatggcccga tgccgtgggt cagtaactgg
     1441 caacaatttg aagccctgtt tcgctgtctg agttacacca cgatgatcga cagcattaaa
     1501 gatctgcact gggatattcg ccccagtcct cattttggca cggtggaggt tcgggtgatg
     1561 gataccccgt taacccttag ccacgcggta aatatggcgg gattaattca ggctaccgcc
     1621 cactggttac tgacggaacg cccgtttaaa catcaggaaa aagattacct gctgtataaa
     1681 ttcaaccgtt tccaggcctg tcgctatggg ctggaaggtg tcattaccga tccgcacact
     1741 ggcgatcgtc gaccgctaac ggaagatacc ttgcgattgc tggaaaaaat cgccccttcc
     1801 gcacataaaa ttggcgcatc gagcgcaatt gaagcactgc atcgccaggt cgccagcggt
     1861 ctgaatgaag cgcagctgat gcgtgatttc gtcgccgatg gcggttcgct gattgggttg
     1921 gtgaaaaagc attgtgagat ctgggccggt gactaagccg ggaattgcct tacagaagaa
     1981 tatccctgac aatggtgttt taacttacat ttaacaatgt tatgaaacac cctttagaaa
     2041 ccttgaccac cgcagcaggc attttgctga tggctttcct ctcttgcctg ctgctgcccg
     2101 cccccgcact ggggctgacg ctggcacaaa aactggtgac cacgttccat ctgatggatc
     2161 ttagtcagct ttacacttta ttgttttgtc tgtggttttt agtgctgggc gctattgagt
     2221 attttgttct gcgctttatc tggcgacgct ggttctcgct ggcggattaa acgtcgatta
     2281 tcgccgtact tcgcggcata ctttgcttat tctccttcgc ctaaaggaac gtttatggat
     2341 aagcaatcac tgcacgaaac ggcgaaacgc ctggcccttg agttaccctt tgtcgagctt
     2401 tgctggcctt ttggcccgga gttcgatgtt tttaaaattg gcggcaagat ttttatgctg
     2461 tcgtcggagc tacgcggcgt cccctttatc aatctgaagt ccgatccaca aaaatccctg
     2521 ttaaatcagc aaatataccc aagcattaag ccagggtatc acatgaataa aaagcactgg
     2581 atttcggtgt atcccggcga ggaaatctcc gaagcgttac ttcgcgatct gatcaacgat
     2641 tcgtggaatc tggtggttga tggtctggct aaacgcgatc aaaaaagagt gcgtccaggc
     2701 taaagcggaa atctatagcg catttttctc gcttaccatt tctcgttgaa ccttgtaatc
     2761 tgctggcacg caaaattact tacacatgga gtctttatgg atatcatttc tgtcgcctta
     2821 aagcgtcatt ccactaaggc atttgatgcc agcaaaaaac ttaccccgga acaggccgag
     2881 caaatcaaaa ctctcctgca atacagccca tccagcacca actcccagcc gtggcatttt
     2941 attgttgcca gcacggaaga aggtaaagcg cgtgttgcca aatccgctgc cggtaattac
     3001 gtgttcaacg agcgtaaaat gcttgatgcc tcgcacgtcg tggtgttctg tgcaaaaact
     3061 gcgatggacg atgcctggct gaagctggtt gttgaccagg aagatgccga tggccgcttt
     3121 gccacgccgg aagcgaaagc cgcgaacgat aaaggtcgca agttcttcgc cgatatgcac
     3181 cgtaaagatc tgcatgatga tgcagagtgg atggcaaaac aggtttatct caacgtcggt
     3241 aacttcctgc tcggcgtggc ggctctgggt ctggacgcgg tacccatcga aggttttgac
     3301 gccgccatcc tcgatgcaga atttggtctg aaagagaaag gctacaccag tctggtggtt
     3361 gttccggtag gtcatcacag cgttgaagat tttaacgcta cgctgccgaa atctcgtctg
     3421 ccgcaaaaca tcaccttaac cgaagtgtaa ttctctcttg ccgggcatct gcccggctat
     3481 ttcccctcag attctcctga tttgcataac cctgtttcag ccgtcatcat aggctgctgt
     3541 tgtataaagg agacgttatg caggatttaa tatcccaggt tgaagattta gcgggtattg
     3601 agatcgatca caccacctcg atggtgatga ttttcggtat tatttttctg accgccgtcg
     3661 tggtgcatat tattttgcat tgggtggtac tgcggacctt cgaaaaacgt gccatcgcca
     3721 gttcacggct ttggttgcaa atcattaccc agaataaact cttccaccgt ttagctttta
     3781 ccctgcaggg gattatcgtc aatattcagg cggtattctg gctgcaaaaa ggcaccgaag
     3841 cggcagatat tctgactacc tgcgcgcagt tgtggatcat gatgtatgcg ctgctttcag
     3901 tcttctcgtt gctggatgtt attttgaatc tggcgcagaa attcccggca gcatcccagt
     3961 taccgctgaa agggatattt caggggatta aactgatcgg cgcgattctg gtcggcattt
     4021 tgatgatctc gctgctgatt ggtcagtcgc cagcgattct gatcagcggt cttggtgcaa
     4081 tggctgccgt gctgatgttg gtatttaaag atccgattct tggtctggtg gcaggtattc
     4141 agctttccgc gaacgatatg ctgaaactgg gcgactggct ggagatgccg aaatacggcg
     4201 cggatggcgc ggtgatcgat attgggttaa ccaccgtcaa agtgcgtaac tgggacaata
     4261 ccattaccac tattcccacc tggtctctgg tttctgactc ctttaaaaac tggagcggga
     4321 tgtcagcatc tggcgggcga cgtattaagc gcagtatcag tattgatgtc accagtattc
     4381 gttttcttga tgaagacgaa atgcaacgtc tgaataaagc gcatttgtta aagccttatt
     4441 taaccagccg ccatcaggaa attaatgagt ggaatcgcca gcaaggttct acggagtcgg
     4501 tattaaacct gcgccgaatg accaatattg gaacctttcg tgcctatctg aacgaatatc
     4561 tgcgtaacca tccgcggatt cgtaaagata tgactttaat ggtacgccaa ctggctccag
     4621 gtgataatgg tttaccgctc gagatctatg cgtttaccaa caccgtggtg tggctggaat
     4681 atgaaagcat tcaggctgat atattcgatc acatatttgc gattgtcgaa gagtttggtc
     4741 tgcgacttca tcagtcgcca accggcaatg atattcgctc tctggcgggt gcatttaagc
     4801 agtaattaaa aaaaccgctc tcatcgaatg gatgagagcg gacatcgttt tgttggatgt
     4861 agcgtgaatg ccttatttcc gacgcagcgt tttaaatgcc acaaacagga atacaatcca
     4921 caccggcagc aggatcgctg acaagcgcat atcatccatc gtgcacatca gcagcaaaat
     4981 catgccgagg aaggcgatgc aaagatagtt gccgaacgga taaagcagcg ccttaaactg
     5041 tgtttcacgc ccctgacgtc gcatcgctgc acgaaaacgc agatgcgcca gacagatcat
     5101 aatccagttc aacagcagcg ttgctaccac cagcgccatc agcagaccaa acgctttttg
     5161 cggcagcaga tagttgatta acaccaccag cgaagtgatc gctccggaaa gcatcagcga
     5221 gttaatcggc acaccgcgac ggctgacgcg agtcaaaaac ttcggcgcat taccctgcac
     5281 agaaaggcca aacagcatgc ggctgttaga gtaaaccccg ctgttataca ctgacagcga
     5341 tgctaccaga atgacgaagt tcagcgcaga agctaccacg ttgctgtcga gattatggaa
     5401 aatcatcaca aacgggctac tgttggattt cacttccacc cacggataga gcgccagtaa
     5461 aaccaccagt gaaccgatgt aaaacagcag gatgcgatac accacctgat ttaccgcttt
     5521 tggaatgctt ttttccggat cgcgcgcttc agcggcagta atcccaatca gctccagacc
     5581 gccgaaggag aacataatta ccgccagcga caaaatcagc ccattccagc cggtggcgaa
     5641 gaaaccaccg tagcgccaga ggttgtcgat actggctttc tcgccgccgt gaccagaaaa
     5701 cagcagccac aggccaaagc cgatcatacc gatgatcgcc agcactttaa tcagcgcaaa
     5761 ccagaactcg gtttcgccat ataagcgcac gttcaccagg ttaacggcgt tgatgataat
     5821 aaagaaggcg gcagcccaaa tccacgttgg aacatccggg aaccagtact gcatatagat
     5881 gcccgcagcg gtcagctctg ccattcccac cagcacgaac attacccagt agttccagcc
     5941 agagaggaag cccgcaaacg gtccccagta tttataggca aagtgggcaa atgaaccgga
     6001 taccggctcc tcaaccacca tttcgccaag ctggcgcata atcaggaaag cgatgatccc
     6061 ggcgacgccg tagcccagca atacagccgg acccgccatc tgaatcgccg ggccaatgcc
     6121 aagaaacaga ccagtaccaa ttgcgccacc caacgcaatc agttgaatat gacggttatg
     6181 taatccgcga tgaagcgtcg gctcttgatt cgacgcagta tcttccgata cggttgacgc
     6241 gtttttcacg cctttcccct gtgtgtcttt tttgttgagg ggcacctttt aacatttagt
     6301 gcccatcgtc gcaagacaca atccacacgg ttaaacgggg tatcctgctt ttatttccgt
     6361 acccgatgtc ggtgcagcca catcagctta tacgccgccg ggataataaa cagcgacagc
     6421 aaaggtgcgg tgatcatgcc gccaatcatc ggcgcggcaa tccggctcat cacctctgaa
     6481 ccagcccccg ttccccacag aatcggcagc agaccggcga taatcaccgc caccgtcatc
     6541 gctttcgggc gcacgcgcag gaccgcgccg tgatataacg cctcatccag cttctgctcg
     6601 ctgaatgttt gtggattatt caacgacggc acggcctcta tggcgtgacg taaatacatc
     6661 agcatcacca cgccaaattc ggcggcgacc ccggcgaggg cgataaagcc agtgcccgtc
     6721 gccacggaaa gatgaaagcc catccaccac agcaaccaga tgccgcccac cagcgcaaac
     6781 ggtacgctgc tgataatcag caacgcttcg cccacccgac ggaacgccag atacaacagc
     6841 acgaagataa tcatcaacgt catcggcacc atgagtttaa gcttatggtt ggcgcgctcc
     6901 agtagctcga actgcccgga gaatgccacg ctggtgcccg gttttaactg cactttttca
     6961 gctatcgctt tttgcaaatc gtgaaccacc gacaccatgt cacgatcgcg ggcatcgata
     7021 taaatccagc tcgtcgggcg cgcattctcg gttttcagca tcgacggtcc ggtagagact
     7081 ttaatgtcgg ccacgtctgc cagggtgatt tgctgcttca tcggcgtcag gatcggcagc
     7141 tggcgcagtg cctgcggact atcgcgccag ctttgcggat aacgcagatt aattggataa
     7201 cgggcaatcc cttccaccgt ttcgccaacc atcgccccgc ccaccgcaga agtcacaaac
     7261 aactgcacat ccgccaccgt cataccgtaa cgtgcggctt tttcacggtt aatctcaacg
     7321 ttgatatagc gcccaccttc cagccgctcg gcaagcgcag aagctacgcc tggcaccgtt
     7381 cgcgctactt cttcaatttg ctcagccatc gcgtcgatat ccgccagcac agtgccggaa
     7441 actttaatgc cgatggggct tttaatgccg gttgagagca tatcgatacg gttacgaatt
     7501 ggcggcaccc acagattcgc cagccccggc agccgcacgg tgttatccag ttcctcaatg
     7561 attttgtcca tcgtcatgcc tggccgccac tgctcctgcg gcttaagctg gatggtcgtt
     7621 tctaccatct ccagcggagc agaatcggtg gcggtttccg ctttcccggt tttgccaaat
     7681 acccgcgcca cttcaggtac gctcataatt agcttgtcgg ttttttgcag catactcgcc
     7741 gcctctgctg cggaaatccc cggcagcgtc gatggcatat acaacaagtc gccttcattg
     7801 atctgcggta aaaattcccc gccaacttta ttgagcggcc agagaaccgt cagcaccgaa
     7861 agcgccgcca ccagcagcgt ggttttcggc cagtgcagta ctttcagcaa cagcggatga
     7921 taaacacgaa tcaaaaagcg attgagcggg ttactgcttt ccggcggaat tttgccacgg
     7981 atccagtagc ccatcaggat cgggatcact acgatcgcca gcagcgccgc acccgccatc
     8041 gcatacgttt tggtgaacgc caacgggcca aacagacgcc cttcctgccc ttccagggtg
     8101 aagatcggga taaacgacaa cgtgataatc agcagactga taaatagcgc cggccccact
     8161 tcaacagacg catcggtgat cacctgccag cgcgttttat tatccagcgt ggcgtcagga
     8221 tgctggtgct gccactcttc cagccgttta tgcgcattct cgatcatgac gatagcagca
     8281 tcgaccatcg ccccgacggc aatcgcaatg ccacccaacg acataatatt ggcattcagt
     8341 ccctggaagt gcatgacaat aaaagcaata cacaacccca gcggcaacga aataatcgcc
     8401 accagcgccg agcgcacatg ccagagaaac agcgcacaga ctaccgccac cacaataaac
     8461 tcttccagca acttgccgct gaggttgtcg atggcgcggt caatgagctg gctgcgatcg
     8521 tatgttgtaa ctatctccac gccttccggc agactacttt tcagcgtttc cagtttgtcc
     8581 ttcacggcgg cgatcacttc tcgggcgttt ttgccggatc gcaggatcac caccccgccc
     8641 gccacttcgc cttcgccgtt tagttcggca atgccccggc gcatctccgg gccaatctgg
     8701 accttcgcaa catcgcgcag ataaacgggc acgccatttt cactggcttt taaaacgatg
     8761 tgattaaagt cgtcgagcgt ttgcagatag ccgctggcgc gcaccatata ttccgcttcc
     8821 gccagttcga tcgacgaacc gcccgcttcc tggtttgaag catccagcgc gctttttact
     8881 tcggcgagac tgatgccata ctgcgccagg cgctggggat cgataaccac ctgatactct
     8941 ttcaccacac cgcccaccga cgccacttcc gcaacgtcag ggatggtttt cagctcatat
     9001 ttgagaaacc agtcctgtaa tgagcgtaaa tcggccagat cgtgcttacc gctgcgatcc
     9061 accagtgcat attcatagat ccagccaaca cccgtggcat ctggccccag ctcggcgctg
     9121 actcccgcag gcagcttacc ctgtacctgg ttgaggtact ccagcacccg cgaacgcgcc
     9181 cagtacggat cggtgccatc ttcgaaaatg acatacacat aagagtcgcc aaactgtgag
     9241 aaaccgcgca cagtcttcgc gccaggcacc gacaacatgg tggtggttag cggataagtc
     9301 acctgatttt caacgatttg tggtgcctga ccgggatagc tggttttaat aataacctgc
     9361 acatcggaga gatccggcag cgcatccact ggcgtattaa tgatggtcca ggtgccccag
     9421 atgctcagaa acaacgcgcc catcagcacc aaaaaacggt tcgccaccga gcgacgaata
     9481 atccattcaa tcattggtta ttccctcaat gcgcatgggt agcactttca gagcgcatcc
     9541 gctccagtgc gccagaaata ttggcttcgg aatcaatcag gaacaggccg ctggaaacca
     9601 ccttttcacc ttccgccaga ccagagcgta atgcggtgac gccttgcgat gcctggaaaa
     9661 cagcaacgcg tttcggtaca aagcgcccgt cggcatcaac ggtaatcacc cgctgttcgc
     9721 tgccggtatc aatcagcgct tgtgacggaa tgagcagcat cggttcgctg gcggtgttga
     9781 gttgcaacca ggcgttcatg cccggtttta gcgcctcgtc ggcgttgtcg acttccagac
     9841 gcagctgcag cgtgcgggtc gcggcatcca cgccaggtag cagcgtccat ttgcggatgg
     9901 tgagtgtttt atccggtcgc gccggaacgg tgagggtaaa ctgcgaggca tctttcacca
     9961 gccaggcgat agactccggg atcgcagcag tgacccacac cgggtccata ccctgaattt
    10021 tcgctaccac gttatctttg gcgatattca ttcccgcgcg cagatcaaac gcggtgatca
    10081 cgccatcaat gggcgctttg agcgtaaagc gagtctggat tttttgcgtg gcgatcaggc
    10141 ggcgaatatc cgcctccggc attcccgcca gtcgcagccg ctcaagaatg ccttcagtct
    10201 gggtcgccgt accgccggtt tcgcgcagca gtaaatactc actctgcgct tccacccagt
    10261 caggaatggt caggtcgaga agcggtgtgc ccttttgtac tttatcgccc acggtaagcg
    10321 gatacacctt gtcgataaac ccggcagcgc gagcctgcac aatggcatac tgatactcgt
    10381 tgtaactgac attcgccggg aaactctggg caaaagtcag cggtccgcgc gtgacggtag
    10441 ccgttttcac ccccagattc tgcgtctgag tcgggtcaat gcgcacacca gacgcagaac
    10501 tctcttcatc ggcatatttc ggcaccagat ccatatccat aaacggcgat ttacctggtt
    10561 tatcgaaccg cgtattggga tacattgggt cgtaccagaa taagatttta cgttctgcgg
    10621 tcgacgtttt ttctgcaggc ggttccgcct ttgcaaccca ggtaaaacct gccgcagaaa
    10681 taataccgcc cgcgatcatg ctgccgataa taagcgcgat ttttttcatc tcattaaacc
    10741 tgggttactg gctgacttta atatcctgta ataaagaaag gttgccctgc tggacaaaat
    10801 taaacgccac tttgtcgccg gttttaattt cactcatttt cgtctgcggg gtgatggtaa
    10861 agcgcatggt catctccggc cagttcacgg cagcaatcgg atcgtgatgg atggtgattt
    10921 ttttgctttc cagatcaata ccctttacca cgccagtggc gctaataacc tgtggttgtg
    10981 cttcgctcat ggtttcatga tgatgttcgt tagcctgggc attaaagcca ataacggtaa
    11041 acagactgaa cattgcgact tgcagtgctt ttttcattta ttctctcctg gagttaaaag
    11101 tcatactcta aataattcga gttgcaggaa ggcgacaagc gagtgaatcc ccaggagctt
    11161 acataagtaa gtgactgggg tgagcgaacg cagacgcagc acatgcaact tgaagtatga
    11221 cgagtatatt gctgtcaacc gccaccaagt gcggtataca aagaaatttc gttaacctga
    11281 cgggcataat tcagatcaag taaagtttgt cgggttgcaa ataaagaacg ctcggcatcc
    11341 agcacttcca gataacttac tgcgccgtgc tgatataatg cccgcgcccg ttgcaaagta
    11401 atttgcagcg atgccagata acgctgctgg gcgctaattt gatcgttcag gctttgacgt
    11461 aatgccagcg catctgccac ttctttaaag gcgttctgga ttttctgttc ataattcacc
    11521 accgactgct gctggcgaat ttcggcgata tccagattgg cctggttgcg tccggcatta
    11581 aaaatgggga tctcaatttt gggtataaaa ttccacatcc cgctgctggc gttaaataat
    11641 gacgatagat cgctactggc ggtcgatatt ccgctggtca ggcttataga cggaaaaaat
    11701 gccgcgcgtg cagcgccaat attggcatta gccgccatta acgcgtgttc agcttccata
    11761 atatccgggc gctgcaataa gatttgcgac gacaatcccg ccggtaattt aacgctttgc
    11821 aggctgtcgc tgtttactgt ctgcgcttgc ggcagcttgc cgtagcttcc cagcaacagt
    11881 tgcaatgcat tattcgcctg cgccagttcc ccctgacgtt tagcgatgtc gctgcgggta
    11941 ctttctatca ccccgcgagc ctgttccagc gccagaacat tactgctacc tgtcaacagt
    12001 tgtttttcga caaacgcata tgactgctga taattacgca gcgtttcttc ggctatttgc
    12061 aattgcgcat acgccagttg ctgattgaaa tagctttgcg cgacattaga aaccagcaga
    12121 atatgcaccg cgcgctgagc ttcctcagtg gctaaataat tttgtcgctc ggcttcgctc
    12181 atgttcttta agcgaccgaa aaaatcgagg tcaaagctgg cgttaaggcc ggtcgaaaac
    12241 tcccgtgtcg tggcggtatt ccctttaaga ttaccgctcc agctgccgct gccctcgcca
    12301 ttgagctgtg ggtagcggtc ggcatcggtc agacgatatt gcgcccgtgc ctcctgcact
    12361 ttcagcgtcg ccatgcgcaa atcccgatta ttcaccagcg cctcgctaat cagcgtcttc
    12421 acctgattat caacaaaaaa ggtgcgccag cccgcgttct gatagttatc tgctgcgtta
    12481 accaggccgt tctggctgag tgagaactgc tgcggcacgg gcattgccgg acgctgataa
    12541 tccggtgcca gtgaacaacc ggttagcgca agggccacac aaaatggcag aagtttacaa
    12601 ggagacatag gctcataatt tctggtgatt ttatgccgcc aactttactc gccaggctct
    12661 gattttccgg tgacagaaaa atgacaaaat tgtcattttg ccaataagcg attgccatct
    12721 gatcccgcta ctctagaatt gcccgggcaa catgcggagg aaatatgaaa ctgttgattg
    12781 tcgaagatga aaagaaaacc ggagaatact tgaccaaagg gttaaccgaa gccggttttg
    12841 tggtcgattt ggccgacaac gggctgaatg gctaccatct ggcgatgacc ggtgattatg
    12901 atctgataat cctcgatatt atgctgccgg acgtgaacgg ctgggatatc gtgcgcatgt
    12961 tacgctccgc caataaaggg atgccgattc tgttgcttac cgcgcttggc accattgaac
    13021 atcgcgtcaa ggggctggag ttgggggcag atgactacct ggtgaagcca ttcgcttttg
    13081 ctgaactgct ggcgcgggtg cgcacattac tgcggcgcgg ggcggcggtg attatcgaaa
    13141 gtcagtttca ggttgccgat ttgatggtcg atctcgtcag ccgcaaagtc acccgcagcg
    13201 gcacgcgcat cactttgacc agtaaagagt ttactctgct ggagttcttc cttcgccatc
    13261 agggcgaagt gctgccccgc tcgcttatcg cctcgcaggt atgggacatg aattttgaca
    13321 gcgataccaa tgctattgat gtggcggtga agcggctgcg cggcaaaatc gacaacgact
    13381 ttgagccgaa gctaattcag accgtgcgcg gcgtgggtta catgcttgag gtgccggatg
    13441 gtcagtaagc catttcagcg cccgttttcg ctggcaaccc gcctgacctt ttttatcagc
    13501 ctggccacca tcgcggcgtt tttcgccttt gcatggatca tgatccactc agtaaaagtt
    13561 cattttgccg agcaggatat taatgattta aaagagatta gcgccaccct tgaacgggta
    13621 ctaaatcacc ctgacgaaac gcaagcccga cgcttaatga cgctggaaga tatcgtcagt
    13681 ggttattcca atgtgttgat ttccctggca gatagtcagg gtaaaacggt gtatcactcc
    13741 cccggtgcgc cggatatccg cgagtttacg cgtgacgcca tacccgataa agacgctcag
    13801 ggtggcgagg tgtatctcct ttccggcccg acgatgatga tgccaggcca cggtcacggg
    13861 catatggaac acagcaactg gcggatgatt aacttgccgg ttggcccgtt ggtggacggc
    13921 aaaccgattt atacgctcta catcgcgctt tcgatcgatt ttcatcttca ttacataaat
    13981 gatttgatga ataaacttat tatgaccgca tcggtaatca gcatcctgat cgtctttatc
    14041 gtactgttgg cggtacataa aggtcacgcg ccgatccgca gcgtcagccg tcaaatccag
    14101 aatattacct cgaaagatct cgacgttcgc ctcgacccgc agaccgtgcc gattgagctg
    14161 gaacagctgg tactgtcgtt caaccatatg atcgagcgta ttgaggatgt ctttacccgc
    14221 cagtccaatt tctcagcgga tatcgctcac gaaattcgca cgccgattac caatctcatc
    14281 acgcaaacgg aaatcgccct cagccagtct cgcagccaga aggagctgga agatgtgctc
    14341 tactctaatc tcgaagagct gacgcgaatg gcgaaaatgg tcagcgatat gctgtttctc
    14401 gctcaggccg ataacaacca gctaatcccc gaaaagaaaa tgctcaacct ggcggatgaa
    14461 gtcggcaaag tgttcgattt tttcgaggcg ttagcggaag atcgcggcgt ggagttgcga
    14521 tttgttggcg acaaatgtca ggttgcgggc gatccgctga tgctgcgtcg ggcgttaagc
    14581 aacctgcttt ctaatgccct gcgttatacg ccacccagtg aggctattgt agtgcgctgc
    14641 cagacggtca atcatcaggt gcaagtttcc gtcgaaaacc ccggtacgcc cattgcgccc
    14701 gagcacttac cgcgattgtt tgaccgtttc tatcgcgttg acccttcccg ccagcgaaaa
    14761 ggtgaaggta gcggtattgg gctggcgata gtgaaatcga ttgttgtcgc gcataaaggc
    14821 acggttgcgg taacgtcaga tgcgcggggg acaaggtttg tgattatgct gccggagaga
    14881 gagtgattat taagttcaaa ttcagggcgt ggtgcatcac ctcct
//
LOCUS       DAPHKZ010000111        14688 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.111, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000111 DAPHKZ010000000
VERSION     DAPHKZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14688
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.111"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            65..631
                     /locus_tag="RH288_003528"
     CDS             65..631
                     /locus_tag="RH288_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4032548.1"
                     /translation="MFKGQKTLTALAISLLFTAPVYAADEGSGEIHFKGEVIEAPCEI
                     HQDDIDKEVELGQVTTSHINQSHHSDAVAVDLRLVNCDLENSSNGSGGKISKVAVTFD
                     SSAKTTGADPILNNTSTGEATGVGVRLMNKDQSNIVLGTATPDIDLAPTSSEQTLNFF
                     AWMEQIDQATPVTPGAVTANATYVLDYK"
     gene            682..3138
                     /locus_tag="RH288_003529"
     CDS             682..3138
                     /locus_tag="RH288_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706516.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV4032549.1"
                     /translation="MDTVNIYRLSFVSCLVMAMPCALAVEFNLNVLDKSMRDRIDISL
                     LKEKGVIAPGEYFVSVAVNNNQISNGQKINWQKKGDKTIPCINDSLVDKFGLKPDIRQ
                     SLPQIDRCIDFSSRPEMLFNFDQANQQLNISIPQAWLAWHSENWAPPSTWKEGVAGVL
                     MDYNLFASNYRPQDGSSSTNLNAYGTTGINAGSWRLRSDYQLNNTDSEDSHEQSGGIS
                     RTYLFRPLPQLGSKLTLGETDFSSNIFDGFSYTGAALASDDRMLPWELRGYAPQISGI
                     AQTNATVTISQSGRVIYQKKVPPGPFIIDDLNQSVQGTLDVKVTEEDGRVNNFQVSAA
                     STPFLTRQGQVRYKLAAGQPRPSMSHQTENETFFSNEVSWGMLSNTSLYGGLLLSGDD
                     YHSAAMGIGQNMLWLGALSFDVTWASSHFDTQQDERGLSYRFNYSKQVDATNSTISLA
                     AYRFSDRHFHSYANYLDHKYNDSDAQDEKQTISLSVGQPITPLNLNLYANLLHQTRWN
                     ADASTTANITAGFNVDIGDWRDISISTSFNTTHYEDKDRDNQIYLSISLPFGNGGRVG
                     YDMQNSSHSTIHRMSWNDTLDERNSWGMSAGLQSDRPDNGAQVSGNYQHLSSAGEWDI
                     SGTYAANDYSSVSSSWSGSFTATQYGAAFHRRSSTNEPRLMVSTDGVADIPVQGNLDY
                     TNHFGIAVVPLISSYQPSTVAVNMNDLPDGVTVAENVIKETWIEGAIGYKSLASRSGK
                     DVNVIIRNASGQYPPLGADIRQDDSGISVGMVGEEGHAWLSGVAENQLFTVVWGEQSC
                     IIHLPERLEDTTKRLILPCH"
     gene            3153..3881
                     /locus_tag="RH288_003530"
     CDS             3153..3881
                     /locus_tag="RH288_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV4032550.1"
                     /translation="MTFIKGLPLMLLTISLGCNAAVQPDRTRIVFNANDKATSLRIEN
                     QSDKLPYLAYSWIENEKGEKSDALLVALPPIQRLEPKATSQVRVVKQASTTQLPGDRE
                     TLFFYNMREIPPAPDKSSDHAILQVAIQSRIKLFWRPAALRKKAGEKVELQLQVSQQG
                     NQLTLKNPTAYYLTIAYLGRNEKGVLPGFKTVMVAPFSTVNTNTGSYSGSQFYLGYMD
                     DYGALRMTTLNCSGQCRLQAVEAK"
     gene            3878..4939
                     /locus_tag="RH288_003531"
     CDS             3878..4939
                     /locus_tag="RH288_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415244.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4032551.1"
                     /translation="MSAGKGLLLVICLLFLPLKSAMALNCYFGTSGGAVEKSEAIQPF
                     AVPGNAKPGDKIWESDDIKIPVYCDNNTNGNFESEHVYAWVNPYPGVQDRYYQLGVTY
                     NGVDYDASLGKSRIDTNQCIDSKNIDIYTPEQIIAMGWQNKICSGDPANIHMSRTFLA
                     RMRLYVKIREMPPHDYQSTLSDYIVVQFDGAGSVNEDPTAQNLKYHITGLENIRVLDC
                     SVNFSISPETQVIDFGKFNLLDIRRHTMSKTFSIKTTKSQNDQCTDGFKVSSSFYTEE
                     TLVEEDKALLIGNGLKLRLLDENASPYTFNKYAEYADFTSDMLVYEKTYTAELSSIPG
                     TPIEAGPFDTVVLFKINYN"
     gene            5091..6137
                     /locus_tag="RH288_003532"
     CDS             5091..6137
                     /locus_tag="RH288_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415243.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDV4032552.1"
                     /translation="MPVLQWGMLCVLSLLLSIGFLAVHLPAALLLGPMIAGIIFSMRG
                     ITLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAVNWPIVLAILLVTLLSSAIVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
                     MLGDNAEAVNQHIVWFPPVSINLLLTILLAVVAGTVGCLLRLPSGTMLIPMLAGAVLQ
                     SGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGM
                     AWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAMQTLRLFSILLTGPA
                     IARFISTYAPKRSA"
     gene            complement(6134..6925)
                     /gene="nei"
                     /locus_tag="RH288_003533"
     CDS             complement(6134..6925)
                     /gene="nei"
                     /locus_tag="RH288_003533"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HDV4032553.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKTYQSQLIGQH
                     VTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTIL
                     LYSASDIEMLRPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
                     QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLEIPRFSYATRGQVDE
                     NKHHGALFRFKVFHRDGEPCERCGSIIEKTTLSSRPFYWCPGCQH"
     gene            complement(6961..7695)
                     /gene="pxpA"
                     /locus_tag="RH288_003534"
     CDS             complement(6961..7695)
                     /gene="pxpA"
                     /locus_tag="RH288_003534"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HDV4032554.1"
                     /translation="MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACV
                     REAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRH
                     VKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVF
                     ADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLH
                     GDGEHALAFARRLRSTFAEKEIVVAA"
     gene            complement(7685..8617)
                     /gene="pxpC"
                     /locus_tag="RH288_003535"
     CDS             complement(7685..8617)
                     /gene="pxpC"
                     /locus_tag="RH288_003535"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpC"
                     /protein_id="HDV4032555.1"
                     /translation="MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLV
                     GNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTL
                     KRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLKDGDRLPIGKSKRDSM
                     EAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKR
                     TTDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQ
                     PIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN"
     gene            complement(8611..9267)
                     /gene="pxpB"
                     /locus_tag="RH288_003536"
     CDS             complement(8611..9267)
                     /gene="pxpB"
                     /locus_tag="RH288_003536"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDV4032556.1"
                     /translation="MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVV
                     EAIPGMNNITVILRNPESLALDAIERLQRWWEESEALEPESRFIEIPVVYGGAGGPDL
                     AVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLLVPA
                     GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPARDEPILLRPGDSVRFVPQKEGVC
                     "
     gene            complement(9290..10033)
                     /gene="ybgI"
                     /locus_tag="RH288_003537"
     CDS             complement(9290..10033)
                     /gene="ybgI"
                     /locus_tag="RH288_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HDV4032557.1"
                     /translation="MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTA
                     SQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
                     GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTDLDVTFIDIPNPA"
     gene            10304..11785
                     /gene="dtpD"
                     /locus_tag="RH288_003538"
     CDS             10304..11785
                     /gene="dtpD"
                     /locus_tag="RH288_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HDV4032558.1"
                     /translation="MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYND
                     THAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSF
                     LYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGY
                     AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLV
                     LLVATPALITILFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFF
                     SMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKE
                     SVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINY
                     SINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES"
     gene            complement(11935..13353)
                     /gene="phrB"
                     /locus_tag="RH288_003539"
     CDS             complement(11935..13353)
                     /gene="phrB"
                     /locus_tag="RH288_003539"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HDV4032559.1"
                     /translation="MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWAT
                     HNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFY
                     NYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLK
                     RLREGMPECVAAPKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQN
                     GAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLNEL
                     IWREFYRHLITYHPSLCKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQL
                     NSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTD
                     AAPYFRIFNPTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQKAGVTLDYPQP
                     IVEHKEARVQTLAAYEAARKGK"
     gene            complement(13350..13859)
                     /locus_tag="RH288_003540"
     CDS             complement(13350..13859)
                     /locus_tag="RH288_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HDV4032560.1"
                     /translation="MNLQRFDDSTLIRIFALHELHRLKEHGLTRGALLDYHSRYKLVF
                     LAHSQPEYRKLGPFVADIHQWQNLDDYYNQYRQRVVVLLSHPANPRDHTNVLMHVQGY
                     FRPHIDSTERQQLAALIDSYRRGEQPLLAPLMRIKHYMALYPDAWLSGQRYFELWPRV
                     INLRHSGVL"
     gene            complement(14010..14688)
                     /locus_tag="RH288_003541"
                     /pseudo
     CDS             complement(14010..14688)
                     /locus_tag="RH288_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT         3539 a         3909 c         3565 g         3675 t
ORIGIN      
        1 tcaattgtca ttttatatat tcttgccacg caacactcta tctcattatt taaaggactc
       61 agttatgttt aaaggacaaa aaacattgac cgctctggcc atatctctgc tattcactgc
      121 acctgtttat gcagctgatg aaggatccgg tgaaattcac tttaaaggtg aagttattga
      181 agcaccgtgt gaaatacatc aggatgatat tgataaagag gttgaactcg gtcaggtgac
      241 caccagccac attaatcagt cacatcacag cgatgccgtt gctgtcgacc tgcgcttagt
      301 caactgtgat ctggaaaact ccagcaacgg ttccggtggc aagatttcta aagttgcagt
      361 cacctttgat agctcagcga aaaccaccgg cgcagatccg attctcaaca acaccagcac
      421 gggtgaagcc accggcgtcg gcgtacgttt aatgaataaa gatcaaagca atatcgtttt
      481 aggcaccgct actccagata tcgacctggc tccgacctcc agcgaacaaa cgctgaattt
      541 ctttgcctgg atggaacaaa ttgatcaggc tacacctgta acgccaggcg cagttacagc
      601 gaatgcgacc tacgtgctgg attataaata agtattactt tggcggcgct atcgccgcct
      661 ttcttcaaat atttatcagg tatggacacc gtgaatattt atcgactctc ttttgtatcc
      721 tgcctggtca tggcgatgcc ttgcgcattg gcggtcgaat ttaatctgaa tgttctcgat
      781 aaatcaatgc gcgaccgcat tgatatttca ttattaaagg aaaaaggagt cattgctccc
      841 ggtgaatatt ttgttagcgt tgcggtgaat aacaaccaaa tcagtaatgg gcaaaaaatc
      901 aactggcaaa aaaagggtga caaaaccatt ccatgcatca atgattcact ggtcgataaa
      961 tttggtttaa aaccagatat ccgtcagtcc ttgccacaga tagatcggtg tattgatttc
     1021 agttcccgac ctgaaatgct cttcaatttc gatcaagcca atcagcaact gaatattagt
     1081 attccgcaag cctggctggc gtggcactca gaaaactggg ctcccccctc tacatggaaa
     1141 gaaggtgttg ccggggtcct gatggattat aacctgtttg ccagcaacta ccgcccacag
     1201 gacggcagca gcagcactaa cctgaacgcc tacggtacca ccggaattaa cgccgggtca
     1261 tggcgcttac gcagtgatta ccagcttaat aacaccgata gcgaagatag ccatgaacag
     1321 tcaggcggaa tatcgcgcac ctatcttttt cgtccattac cgcaattagg ctctaaatta
     1381 accctcggcg aaaccgattt cagttccaat attttcgatg gtttttctta tactggcgcg
     1441 gcactggcga gtgacgatcg aatgttgcca tgggagctac gcggatacgc cccacaaatt
     1501 agcggtattg cacagaccaa tgccacggtg acgatcagtc aatcaggtcg cgtcatttac
     1561 cagaaaaaag tccctccggg accgtttatt attgatgacc tcaatcagtc tgttcagggc
     1621 acgcttgatg tcaaagtgac ggaagaagat ggtcgggtga acaatttcca ggtttcggca
     1681 gcatcgacgc ccttcctgac tcgtcaggga caggttcgct ataaactggc cgcgggtcag
     1741 ccacggccct ccatgtcaca tcaaactgaa aatgaaacct tttttagcaa tgaagtttcc
     1801 tgggggatgc tgtcaaacac ctcgctgtac ggcggcctgc tgctttctgg tgatgactac
     1861 cattctgccg caatgggtat tgggcaaaat atgctgtggc ttggtgcgct gtcgtttgat
     1921 gtcacgtggg ccagtagcca ttttgatact cagcaggacg agcggggctt aagctaccgt
     1981 tttaattaca gcaaacaagt ggatgccacc aacagcacga tttcgctcgc cgcttatcgc
     2041 ttctcagatc gtcattttca cagctacgcc aactatctgg atcacaaata caacgacagc
     2101 gatgcgcagg acgaaaaaca gacgatcagc ttatccgtgg gccaaccgat taccccacta
     2161 aacctcaatc tttacgccaa cctgctacat caaaccaggt ggaatgcaga cgcctccacg
     2221 accgccaaca tcacagcagg ttttaatgtt gatattggtg actggagaga tatctcgatt
     2281 tcgacgtcat tcaatacgac ccactacgaa gataaagatc gcgacaacca gatttatctg
     2341 tcaatttcgc tccccttcgg taacggtggt cgggttggct atgacatgca aaacagtagc
     2401 cacagcacca tacaccgcat gtcgtggaac gatacgctgg atgaacgtaa tagctggggc
     2461 atgtctgccg gactgcaatc cgatcgtccg gacaatggag cccaggtgag cggtaactat
     2521 cagcatctga gttcagcggg tgagtgggat atttctggta cctatgccgc caatgattac
     2581 agttccgtca gcagcagctg gagcggttct ttcaccgcaa cccaatatgg tgcagcgttt
     2641 catcgccgca gctctaccaa tgaaccacgc ctgatggtca gcaccgatgg cgtggcagat
     2701 attccggttc agggcaatct cgactacacc aaccattttg gcattgcggt ggtgccgttg
     2761 atttccagtt atcagccttc caccgtggcg gtgaacatga atgacttacc cgacggcgta
     2821 acagttgcag aaaacgtcat caaggaaaca tggattgaag gcgcgatagg ttacaaatca
     2881 ctggcttccc gttccggtaa agacgttaac gtcatcatac gcaacgccag cggtcagtac
     2941 cctcccctcg gtgcggatat ccgccaggat gatagcggca ttagcgtggg tatggttggc
     3001 gaggaaggac atgcctggtt aagcggtgtc gctgaaaatc aactgtttac cgtggtctgg
     3061 ggtgagcaaa gctgcattat tcatctgcca gaacgtctgg aagacacgac caaacgcctg
     3121 attttacctt gtcattaatt aaggaaaaga gaatgacatt tattaaagga ttacccttaa
     3181 tgttgttaac catcagcttg ggctgcaatg ctgcggtgca acccgatcgc acacgcattg
     3241 tgtttaacgc caatgacaaa gccaccagcc tgcgtatcga aaaccaaagt gacaaactgc
     3301 cttatcttgc ttattcctgg atagaaaatg aaaaagggga gaaaagcgat gctcttctgg
     3361 tcgctttgcc ccctattcaa cgtctggaac cgaaagcgac atcgcaggtg cgggttgtga
     3421 aacaagcctc aaccacacaa ttacctggcg atcgcgaaac gctatttttc tacaatatgc
     3481 gcgaaattcc tcccgctccg gataaaagca gcgaccatgc gatacttcag gtcgctattc
     3541 aaagtcgtat taaattgttc tggcgaccgg ctgcattacg caagaaagca ggagaaaagg
     3601 tcgaactgca gttacaggtc agccagcagg gcaaccaact gacactgaaa aatcctaccg
     3661 cgtattatct gaccattgcc tatctgggga gaaatgaaaa aggcgttctc ccaggcttca
     3721 aaaccgtgat ggttgcacct tttagtacgg tcaacacaaa caccggaagt tatagcggca
     3781 gccagtttta tctcggttat atggatgatt acggcgcatt acgcatgacg acgctcaact
     3841 gcagcggaca atgccgttta caagcagtgg aggcgaaatg agtgctggca agggattgtt
     3901 gctcgtcatc tgcctgttat ttctgccgtt gaagtctgca atggcgctga actgctattt
     3961 tggtacatct ggtggcgcag tagaaaaatc agaagcgatt caaccgtttg ctgtaccagg
     4021 caatgccaaa cccggtgata agatctggga atctgacgat attaaaattc ccgtctattg
     4081 tgacaacaat accaacggca actttgaaag cgagcatgtc tacgcctggg taaaccccta
     4141 tccgggggtg caggatcgtt attatcaact cggcgtgaca tacaacggtg tcgattacga
     4201 tgccagtctg ggaaaaagtc gcatcgacac taaccagtgt atcgacagta agaacattga
     4261 tatttatacc cctgagcaga tcatcgcgat gggatggcag aacaaaattt gctcgggcga
     4321 tcccgctaat attcatatgt cgcgtacctt tctcgctcgc atgcggttat acgtcaaaat
     4381 acgagaaatg ccgccgcatg attatcaaag tacgcttagc gactatatcg tcgtgcaatt
     4441 tgacggtgcc ggtagcgtta acgaagaccc tactgcccaa aacctgaaat atcatattac
     4501 tggtctggaa aacattcgcg tgctggattg cagcgtcaat ttttccattt caccggaaac
     4561 acaggtgatt gattttggta aatttaattt gctggatata cgtcgccaca caatgtcgaa
     4621 aacgttcagt attaaaacga ccaagagcca aaacgatcaa tgcaccgacg gatttaaagt
     4681 cagttcctcc ttttataccg aagaaacgtt ggttgaagaa gataaagcat tgttgattgg
     4741 taatggtctg aagctacgtt tactggatga aaacgcctcg ccttatacct tcaataaata
     4801 tgctgaatac gccgatttca ccagtgacat gttggtctac gaaaaaacct atacggctga
     4861 actttcgtcc attccaggca cccccatcga ggctggcccc ttcgatacag tggtgctttt
     4921 taagattaac tataactgat ttaccatgat gccctttgcc gccggaaagg gcatctcttt
     4981 cagaaaattg ctgattttcc ccttttcctt gattgctgtt attttttcct ggcccagctt
     5041 tctttatgct gtatcgatac accaaagaga aaataatgag ggagcgaagg atgccagttt
     5101 tgcagtgggg aatgttatgt gtgctatcac ttctcctttc tattggtttc ctcgcggtac
     5161 atctcccggc ggcgctatta cttgggccga tgatcgccgg gatcatcttt agtatgcgcg
     5221 gaattactct gcaacttccc cgctctgctt ttctcgccgc ccaggccatt cttggctgca
     5281 tgattgcgca aaacctcact ggttcgattc tcaccaccct ggccgtcaac tggccgatcg
     5341 tgcttgcaat tttactggta acgctgcttt ccagcgccat tgtgggttgg ttattggtgc
     5401 gctatagctc attgcctgga aataccggtg cctggggctc ctctcctggc ggcgcggcgg
     5461 caatggtcgc tatggcgcaa gattacggcg cagatattcg cctggtggcg tttatgcaat
     5521 atctgcgagt gctgttcgtc gcgggggccg ctgttctggt cacccgcatg atgctgggcg
     5581 ataacgctga agcggttaac cagcatatcg tctggttccc gccagtgagc attaatctcc
     5641 tgcttactat tttgctcgcg gtcgttgccg gtacagtggg atgcctgctg cgtcttcctt
     5701 ccggcacgat gctcatcccg atgctggcgg gcgcagtgct ccagtctggt cagctcatca
     5761 ccatcgaact accggaatgg ctgctggcga tggcgtatat ggcaattggc tggcggattg
     5821 gtcttggttt cgataaacaa atcttactgc gggcactacg cccgctaccg caaatcctgc
     5881 tgtcgatttt tgctctgctg gctatttgtg cgggtatggc gtgggggctg acccggttta
     5941 tgcacattga ttttatgact gcctacctcg ccaccagccc cggcgggctt gataccgtgg
     6001 cggtcatcgc cgcagggagc aatgccgata tggcgctcat tatggcgatg caaaccctac
     6061 gcctgttcag tattttgctg acagggcctg ccattgcgcg gtttatttca acctatgcgc
     6121 cgaagcggtc ggcctagtgc tggcagccag ggcaccagta aaacgggcga gatgacagcg
     6181 tggttttctc aatgatgctg ccacaacgtt cgcacggttc gccatctcga tgaaaaacct
     6241 taaagcgaaa cagcgcccca tgatgcttat tctcatccac ctgcccccgc gtagcgtagg
     6301 aaaatcgagg aatctccagt aacgcgtgtg cgagtgcatc cagttgcgcc gcattgagat
     6361 ctttcgcttt atgatttcca gtcaacccaa cctgccagag gatctccacc cgcaaataat
     6421 tgccaagccc agccagaaac gcctgatcga gcagtaatcc tgcaaactga cggttacgaa
     6481 agcgcggtga caataaccgt tcctttacca cctccggcgt cagattcgga tccagcacat
     6541 cgggaccaac gcgttgtaaa aacggatgcg tggtcagttg ttccggcctc aacatctcaa
     6601 tatccgaggc gctataaagc agaatggttt tgtcagccgt ttgcagtttt acccgcaata
     6661 ctcgcgtggt ctgcggctct tcgccggtat caaccacgcg ccagacgccg taaagctgat
     6721 tatggctgta gagcgttaag tcgttggaaa aatgagttaa caacgcctta ccacgcgttt
     6781 ccacatgggt aacgtgttga ccgataagtt gtgattgata agtttttaac tgcgggaagg
     6841 caaaccagac atcagttagt ggtttgcctt tgatcgccgc ctccaggtta tccgctgcac
     6901 ggcggatctc cgggccttca ggcatggtga tatccttttt tcattcttta ttaatcgggg
     6961 ttatgctgcg acaacaatct ccttttcggc aaatgtagag cgtagtcggc gggcgaacgc
     7021 cagtgcgtgc tcgccgtcgc catgcaggca gactgtttgc gccgtgaccg ttgcccattc
     7081 gccggtgata cttttgactc tgccgtgttg caccatctct agcgtttgcg ccagcgcctg
     7141 ttcttcgttt tcaatcaacg cgcctggctg acttcgcggc accagcgagc cgtcagcctg
     7201 ataaccgcga tcggcaaaca cttcctcgcg cgttgtcagg ccatattgct tgcctgcacg
     7261 aatcagctcg cttcctgcca gcccaacgag aatcaatgcc ggatcgcaag cgtataccgc
     7321 tctggcgatg gcgtctgcca gttgtgcttc tttcgccgcc tggttgtaca acatgccgtg
     7381 cggtttgaca tgacgcatta cgccgccttg cgcacgggca atcgttgcca gcgcgccaat
     7441 ttgatacagc gtctgggcgt aaacggtttc tggcggcagc tgcatggcgc tgcgaccaaa
     7501 attttccctg tcgggaaaac tcgggtgagc gccaatcgcg acaccatttt ttattgcttc
     7561 acgcacgcaa gcctgcatgg tttgggcatc gcctgcatga aatccacaag caatattggc
     7621 agaggaaacc agcgttaata gctctgcgtc gctggcgcag ccttcgccca gatcggcgtt
     7681 caggtcaatt ttcattgtgc agccgccacg ctaattgttc aaaataacgt tgctgatctt
     7741 gccgcgcttt cagtgcctct tccagtgaac actggacaaa atgaatcggc tgaccgagcg
     7801 gaatttgcgc cagatggtac atatcagcct caatgataca ggcaatacgc gggtaaccac
     7861 cggtggtctg tgcgtcgttc atcaacacaa tcggctgccc gttatgtggc acctgcacca
     7921 cgcccggtaa caaaccgtga gataacagtt cgcgatcggt ggtgcgtttt aaaatttgcc
     7981 cctgtaagcg atagcccatg cggttacttt gcgagctaag ctgccagggc gaacgccaga
     8041 atgcatcctg cgaggcgcga tcgaactcat gatattccgg ccccggcaag gcgcgaatgc
     8101 ggttgcccca cagcagctgt ttaacgccct gcgcttccat agaatcacgc ttcgatttgc
     8161 caatcgggag tcggtcacca tccttcagta aacggccttc cagcccgcca atccccactt
     8221 tgagatcggt gctgcatgag cccattaccg gcggaacatc aataccaccc gcgaccgcca
     8281 gataactgcg catcccgtgc tgcgggcgtt taagcgttaa acgctggcct gctttcatcg
     8341 gcaatcgcca gccggtccag acggcattat catccagccg cgcttcgcaa ccggcacccg
     8401 tcagagcaaa ccacccatca gtttcgaact caacagttaa ctgaccgagc gtgatctcca
     8461 gcgcgggggc attggcgtca ttacccacca gtaggttagc aatgcgtaac gcgggcatat
     8521 ccagtgcgcc gcagtggctg atacccgact ggcgaaaacc gtgacgaccg ccatcctgca
     8581 cagtggtata catgcccgca cgaataatct tcagcatact ccctccttct gcggtacaaa
     8641 gcgcacgctg tctcccggac gtaataagat gggttcgtca cgcgccggat caaacaggct
     8701 gagtgaggta tgaccaatca actgccagcc acccggcgtt gccagcggat aaacaccagt
     8761 ctgcggcccg ccgatcccga cagaacctgc cggaacgagt aagcgcggtt cagcgcgccg
     8821 tggcgtgtgt agttgttccg gcaaactccc gagatacggg aagcccggtt gaaaacctaa
     8881 aaaccagacc acgtattcca cggaggagtg caattcaaca acctgttttt cgctcaaccc
     8941 gcaatgcgcc gcgaccaccg ccaaatccgg tccgcctgca ccaccgtaaa ccaccggaat
     9001 ttcaataaag cgagactccg gctccagcgc ctcgctctcc tcccaccagc gttgcaaacg
     9061 ctctatggca tccagcgcca gcgactcagg attacgcaaa atcaccgtga tattgttcat
     9121 gccgggaatg gcttcaacca cattcggcat atccaccaga cgctgcgcca gtcgccagat
     9181 ccgtttctgg ctagccagcg tcaccggcgg ttccagttcc agcactaccg ccgtttcacc
     9241 tatcagataa caacgcgctc gttgcacttt cgatccctct gattattcgt tatgcaggat
     9301 taggaatatc aataaaggtc acatcaagat cggtattttc attcagccac tcgctcaatg
     9361 cgcgaatacc accacgttca gtggcatggt gacctgcagc ataaaaatgc aatccctgct
     9421 cgcgggctga atgaatggtc tgttcagaaa cttcgccagt aataaaagca tccacgccaa
     9481 aacgcgcggc gctatcgata aaactttgcc cgccgcccgt gcaccaggcg acgcgctgga
     9541 ccacctcagg tccggtatcg ccacaccata acggcttacg tcccagacgc gcttcaatcc
     9601 aggaagccag ctccagtccc ggcacaggca tggtcagttc gccccacggc accaacggct
     9661 caatttcgcc catgaccgtg atccccagta acgccgccag ctgtgcgtta ttgcccagct
     9721 caggatgtgc gtcaagcggc aaatgccagc catacaggtt gatatcattc gccagcaacg
     9781 tttttaaacg gttacgcttc attccgcgaa tgaccggaga ctctcctttc cagaagtagc
     9841 catgatgcac aatgaccgca tccgcgccca gacgcactgc ctcatcgagc aaagcctggc
     9901 tggcggtgac accggtaaca attttttgca ccgtctcttt gccttccacc tgcaaaccat
     9961 tcggcgcgta atcactaatc gccgcgctgt tcagtttttc gttaatcagt tgttccagtt
    10021 cggtgttttt catcttcgcg ccttccgtat tctgatagct acaccgttaa catagcgtta
    10081 cctcgccagt tcgtcgatag ccaatctttt gacatattaa gaaacaaacc cgacgccaaa
    10141 agacgcaaat tgtttatatc atcacgcttc agctaatgta tatttatgca atcagacagc
    10201 atattgcata aataatcaga tctgtatcaa agttttaact ttaaggaaac acaagcacgc
    10261 cgcgcaacta ttacgtgacg ttgccgtcaa ttgtggaatt attatgaata aacacgcatc
    10321 acagccgcgc gctatttact atgtcgttgc gctgcaaatc tgggaatatt ttagctttta
    10381 cggcatgcgt gccctgctga ttctctatct caccaatcaa ctaaaataca acgatactca
    10441 cgcctacgag ttatttagcg cctactgttc gctggtgtat gtcacgccaa tcctcggtgg
    10501 ctttttggcg gataaagttc tcggcaatcg catggcggtg atgctggggg cgttgttgat
    10561 ggcgatcggt catgtggtgc tgggtgccag tgagatccat ccgtcattcc tctatctgtc
    10621 cctggcgatt atcgtctgcg gctatggcct gtttaaatct aacgtaagct gtctgctcgg
    10681 cgagctgtat gagccaaccg atccgcgtcg tgatggcggt ttctcgctga tgtatgcggc
    10741 gggtaacgtg gggtctatta tcgcacctat cgcctgtggt tacgcccagg aagagtacag
    10801 ctgggcgatg ggctttggcc tggcggcggt tggcatgatc gcgggtctgg tcattttctt
    10861 atgtggcaat cgtcatttca ctcatacccg cggcgttaac aaaaaagtac tgcgtgcgac
    10921 aaactttctc ctgccgaact ggggatggct gctggttctg ctggtggcaa cgcctgcact
    10981 gattaccata ctgttctgga aagagtggtc ggtatacgcc ttaattgtcg cgactattat
    11041 tggcctgggt gtactggcaa aaatttatcg caaagcagaa aaccagaaac agcggaagga
    11101 gctggggctg attgtgacgc tcaccttctt cagtatgttg ttctgggcct tcgcacaaca
    11161 gggcggtagc tcgattagcc tttatatcga ccgcttcgtt aaccgcgata tgtttggtta
    11221 taccgttccg accgcgatgt tccagtcgat taatgccttc gcagttatgc tgtgcggtgt
    11281 gttcctggcg tgggtggtaa aagagagtgt cgcgggtaat cgtaccgtgc gcatctgggg
    11341 gaaatttgct cttggccttg gcctgatgag cgccggattc tgcattctga ccttaagcgc
    11401 ccgctggtcc gcaatgtatg gtcactcttc tctgccactg atggtattag gcctggcggt
    11461 gatgggcttt gcggaactgt ttatcgaccc ggttgccatg tcgcaaatta cgcgcattga
    11521 aatccccggt gtgaccggcg tattaaccgg catctacatg ctgctttctg gcgcgatcgc
    11581 gaactatctg gcgggcgtga ttgccgatca gacatcgcag gcttcgtttg atgcttccgg
    11641 ggcgatcaac tactccatca atgcatatat tgaagtattt gatcaaatta cctggggcgc
    11701 actggcgtgt gtaggactgg tactgatgat ttggctgtat caggcgctga aattcagaaa
    11761 ccgcgcgctg gcgctggagt cttaataggc cagcaccgat gcctgatgcg acgcttgacg
    11821 cgtcttatca ggcctacgta tttcctgcaa tttattgaat ttgcacaaat ttgtaggctg
    11881 gataaggcgt tcacgccgca tccggcatct gggctcgatt gcctgacgcg tctgttattt
    11941 ccccttccgc gccgcctcat acgctgccaa cgtttgtact ctcgcttctt tgtgctcgac
    12001 tatcggttgc ggataatcca gcgtcacacc tgctttctgc gcccacttcc acggctcatg
    12061 caccactttc cctggcacat cgcgcagttc cggtagccac tggcggataa actcgccctc
    12121 atgatcaaat ttctcgccct gggttgtcgg gttgaaaata cgaaaatacg gcgctgcatc
    12181 ggttccggtt gaagcggccc actgccagcc accgttattg gctgccaaat caccatcaat
    12241 cagctgcgac atgaaatatc gctcgccttc gcgccagtcg atcaataaat ctttcaccag
    12301 aaaactggct gtaatcatcc gtagcctgtt atgcatccag ccagtgctgt taagctgacg
    12361 catagcggca tcaacaatcg ggtatcccgt tttgccttcc tgccaggcct gtaaatgtgc
    12421 gggattgctc tgccactgta cacgatccgt ccaggcaata aatggacgat gtttacacaa
    12481 cgaggggtga tacgttatca ggtgacggta aaactcgcgc cagatcagct cattaagcca
    12541 gacactaccg gccccaccgt ccagcgcctg cggctgttca gccaacaagc gatgcaagca
    12601 ctggcgaggc gataacccgc ccgttgccag gctggccgac aaacggctgg tgccttccac
    12661 tgccggaaaa tctcgttgtt gctcatattc tccggcaccg ttctggcaaa actggcgtaa
    12721 ttgcgcaatc gccgcttttt cttccaccgg aaaatgcgca gtatcgaaag actgacgagg
    12781 ataattcagc gtaatggatg gcgagggctc tatcgatccg ctactacgaa cttttggcgc
    12841 agcgacgcac tccggcatcc cttcccgcag ccgtttcagc caggcattct taaaaggcgt
    12901 aaagactttg tacatctcgt gattaccggt catcaccgcg ccaggcggca ggatcacgct
    12961 gtcatcaaat ccttcacaca ccacgttacg cagcgctctt tcaacttcca catcccgcgc
    13021 ccgctcattc acttcatact gatagttata aaacaggtgg gtaacgctgt tttccgcgca
    13081 cacctgttta actatttcga cactggcgac aaagtcatcc acttcacgga acaataaagg
    13141 aatacctttt tccgcaagcg ctatttgtag cccattcagt tgagcattga taagttcagc
    13201 ctgacgcggc gacatgttat gcgtcgccca ctggcgtggt gtagcgatat acaacgccag
    13261 cacgcgtgca gacgaattgc ggcaggcggc agccagtgcg agattatcgt gcagacgtaa
    13321 atcctggcga aaccagacca gatgggtagt cataaaactc ctgaatggcg caagttaatc
    13381 acacgcggcc aaagttcgaa ataacgctgc cctgaaagcc aggcgtcagg ataaagcgcc
    13441 atatagtgtt tgatacgcat cagcggcgca agaagtggtt gctcgccacg gcgataactg
    13501 tcgataagcg cagccagctg ctggcgttct gtggaatcaa tatgcgggcg aaaataaccc
    13561 tgaacgtgca tcaaaacatt ggtgtgatcg cgcgggttgg cggggtgaga aagcaaaaca
    13621 actacgcgtt ggcggtactg gttgtaatag tcatccagat tttgccactg gtgaatatca
    13681 gccacgaacg ggccaagttt gcggtactcc ggctgagaat gcgccagaaa gacgagttta
    13741 tagcggctgt gataatcgag aagcgccccg cgcgttaagc catgttcttt cagtcgatgt
    13801 aactcatgaa gggcaaagat acggattagg gtgctgtcat caaatcgttg tagattcatt
    13861 actgctcctg agcggtttac aggagtaagt gtagacgttg agaaatgata tttgtgaagt
    13921 taatcctgtt gtagcaggac aaatttacga aagcctgctc cccgcaagga ctgacgtcag
    13981 gtagtttcta accatagctg ccctttctat tcaaacgtga aatcaataag ctcatcaggg
    14041 acatcgcaaa caatatgaag acgggtttct tctctgccgt gactcttttc actaattgcg
    14101 taactgtcat gcttgggatt atttaattct ttcagcggaa atttttcctc gaaggcttta
    14161 tttagccgcc cctggtttcc ttttacagcg aataaataat cacctccctg tttttgtatc
    14221 ttctctgcaa tatctttctg gcaacccatc gcatcggttt tgatgatttt tcctttaata
    14281 tccagcatgt taagaagttc agggatagct gtgatctcat tggatttctt atccgtcttg
    14341 atctgtccga tgaccagact gtgcattgtt gagaacgcac taatgacatg aatcgctccc
    14401 ttacggcgac tcttgtcata agaatgccgg tgtatttttc catcaattgc gatgacgtct
    14461 ttatcatctg aagaatggta gtcaagcatc cagttaataa agctctcatg aaatttcgca
    14521 ggacagatac aggatacaac tctggcaatg gtatcgtgaa caggaatacc attttcaaaa
    14581 tcaccatatt gcttcaaaaa atcgggatgt gtttccccaa aatcctctat atcttcccag
    14641 ccttctgcac cagaaataac ggcacaaata gtcaacagta gaatatcc
//
LOCUS       DAPHKZ010000112        14523 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.112, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000112 DAPHKZ010000000
VERSION     DAPHKZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14523
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.112"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(93..440)
                     /gene="trbA"
                     /locus_tag="RH288_003542"
     CDS             complement(93..440)
                     /gene="trbA"
                     /locus_tag="RH288_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HDV4032561.1"
                     /translation="MSEDYLKMFTGVVLLIFVIIAGYFFSERNDRKMFLLSSLVFLVI
                     NIACLYVLTASLWFLCGAIMSQGAALVVSIVAAALPDVTSFDRFRRIFICIVLSSVWS
                     GVMWFFIRGLMTG"
     gene            complement(456..1199)
                     /gene="traF"
                     /locus_tag="RH288_003543"
     CDS             complement(456..1199)
                     /gene="traF"
                     /locus_tag="RH288_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TraF"
                     /protein_id="HDV4032562.1"
                     /translation="MNKALLPLLLCCFIFPASGKDAGWQWYNEKINPKEKENKPVPAA
                     PRQEPDIMQKLAALQTATKRALYEAILYPGVDNFVKYFRLQNYWTQQAGLFTMSARKA
                     MLAHPELDYNLQYSHYNGTVRNQLAADQAQQRQAIAKLAEHYGIMFFYRGQDPIDGQL
                     AQVINGFRDTYGLSVIPVSVDGVINPLLPDSRTDQGQAQRLGVKYFPAMMLVDPKQGS
                     IRPLSYGFISQDDLAKQFLNVSEDFKPNF"
     gene            complement(1192..1449)
                     /gene="trbE"
                     /locus_tag="RH288_003544"
     CDS             complement(1192..1449)
                     /gene="trbE"
                     /locus_tag="RH288_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbE"
                     /protein_id="HDV4032563.1"
                     /translation="MKVIFTSNRFIDFLIRLLITAIVISPVIIWSWDTVKETTADGML
                     AAAFVILYSGVLLFILYFCFSALTDLQKPDERKSDERNEDE"
     gene            complement(1476..3284)
                     /gene="traN"
                     /locus_tag="RH288_003545"
     CDS             complement(1476..3284)
                     /gene="traN"
                     /locus_tag="RH288_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system mating-pair
                     stabilization protein TraN"
                     /protein_id="HDV4032564.1"
                     /translation="MKRILPLILALVAGMAQADSNSDYRAGSDFAHQIKGQGSSSIQG
                     FKPQESIPGYNANPDETKYYGGVTAGGDGGLKNDGTTEWATGETGKTITESFMNKPKD
                     ILSPDAPFIQTGRDVVNRADSIVGNTGQQCSAQEISRSEYTNYTCERDLQVEQYCTRT
                     ARMELQGSTTWETRTLEYEMSQLPAREVNGQYVVSITSPVTGEIVDAHYSWSRTYLQK
                     SVPMTITVLGTPLSWNAKYSADASFTPVQKTLTAGVAFTSSHPVRVGNTKFKRHTAMK
                     LRLVVRVKKASYTPYVVWSESCPFSKELGKLTKTECTEAGGNRTLVKDGQSYSMYQSC
                     WAYRDTYVTQSADKGTCQTYTDNPACTLVSHQCAFYSEEGACLHEYATYSCESKTSGK
                     VMVCGGDVFCLDGECDKAQSGQSNDFAEAVSQLAALAAAGKDVAALNGGDVRAFTGQA
                     KFCKKAAAGYSNCCKDSGWGQDIGLAKCSSDEKALAKAKSNKLTVSVGEFCSKKVLGV
                     CLEKKRSYCQFDSKLAQIVQQQGRNGQLRISFGSAKHPDCRGITVDELQKIQFNRLDF
                     TNFYEDLMNNQKIPDSGVLTQKVKEQIADQLKQAGQ"
     gene            complement(3281..3919)
                     /gene="trbC"
                     /locus_tag="RH288_003546"
     CDS             complement(3281..3919)
                     /gene="trbC"
                     /locus_tag="RH288_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TrbC"
                     /protein_id="HDV4032565.1"
                     /translation="MKLSMKSLAALLMMLNGAVMASENVNTPENRQFLKQQENLSRQL
                     REKPDHQLKAWAEKQVLENPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPE
                     EGLKRMLGETRHYGIPATLRGMVNNDLKTTAEAVLSLVKDGATDGVQIDPTLFSQYGI
                     RTVPALVVFCSQGYDIIRGNLRVGQALEKVAATGDCRQVAHDLLAGKGDSGK"
     gene            complement(3928..4920)
                     /locus_tag="RH288_003547"
     CDS             complement(3928..4920)
                     /locus_tag="RH288_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus assembly protein TraU"
                     /protein_id="HDV4032566.1"
                     /translation="MKRRLWLLMLFLFAGHVPAASADSACEGRFVNPITDICWSCIFP
                     LSLGSIKVSQGKVPDTANPSMPIQICPALPPLFRRIGLAIGYWEPMALTDVTRSPGCM
                     VNLGFSLPAFGKTAQGTAKKDEKQVNGAFYHVHWYKYPLTYWLNIITSLGCLEGGDLD
                     IAYLSEIDPTWTDSSLTTILNPEAVIFANPIAQGACAADAIASAFNMPLDVLFWCAGS
                     QGSMYPFNGWVSNESSPLQSSLLVSERMAFKLHRQGMIMETIGKNNAVCNEYPSPILP
                     KERWRYQMVNMYPDSGQCHPFGRSVTRWETGKNPPNTKKNFGYLMWRKRNCVFL"
     gene            complement(4917..5549)
                     /gene="traW"
                     /locus_tag="RH288_003548"
     CDS             complement(4917..5549)
                     /gene="traW"
                     /locus_tag="RH288_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TraW"
                     /protein_id="HDV4032567.1"
                     /translation="MRCRGLIALLIWGQSVAAADLGTWGDLWPVKEPDMLTVIMQRLT
                     ALEQSGEMGRKMDAFKERVIRNSLRPPAVPGIGRTEKYGSRLFDPSVRLAADIRDNEG
                     RVFARQGEVMNPLQYVPFNQTLYFINGDDPAQVAWMKRQTPPTLESKIILVQGSIPEM
                     QKSLDSRVYFDQNGVLCQRLGIDQVPARVSAVPGDRFLKVEFIPAEEGRK"
     gene            complement(5546..5932)
                     /gene="trbI"
                     /locus_tag="RH288_003549"
     CDS             complement(5546..5932)
                     /gene="trbI"
                     /locus_tag="RH288_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TrbI"
                     /protein_id="HDV4032568.1"
                     /translation="MSSTQKPADVMAERRSHWWWTVPGCLAMVLLNAAVSYGIVRLNA
                     PVTVAFNMKQTVDAFFDRASQKQLSEAQSKALSARFNTALEASLQAWQQKHHAVILVS
                     PAVVQGAPDITREIQQDIARRMRAEP"
     gene            complement(5929..8556)
                     /gene="traC"
                     /locus_tag="RH288_003550"
     CDS             complement(5929..8556)
                     /gene="traC"
                     /locus_tag="RH288_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HDV4032569.1"
                     /translation="MNNPLEAVTQAVNSLVTALKLPDESAKANEVLGEMSFPQFSRLL
                     PYRDYNQESGLFMNDTTMGFMLEAIPINGANESIVEALDHMLRTKLPRGIPLCIHLMS
                     SQLVGDRIEYGLREFSWSGEQAERFNAITRAYYMKAAATQFPLPEGMNLPLTLRHYRV
                     FISYCSPSKKKSRADILEMENLVKIIRASLQGASITTQTVDAQAFIDIVGEMINHNPD
                     SLYPKRRQLDPYSDLNYQCVEDSFDLKVRADYLTLGLRENGRNSTARILNFHLARNPE
                     IAFLWNVADNYSNLLNPELSISCPFILTLTLVVEDQVKTHSEANLKYMDLEKKSKTSY
                     AKWFPSVEKEAKEWGELRQRLGSGQSSVVSYFLNITAFCKDNNETALEVEQDILNSFR
                     KNGFELISPRFNHMRNFLTCLPFMAGKGLFKQLKEAGVVQRAESFNVANLMPLVADNP
                     LTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGG
                     FAVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERVRDQLSVMASPNG
                     NLDEVHEGLLLQAVRASWLAKENRARIDDVVDFLKNASDSEQYAESPTIRSRLDEMIV
                     LLDQYTANGTYGQYFNSDEPSLRDDAKMVVLELGGLEDRPSLLVAVMFSLIIYIENRM
                     YRTPRNLKKLNVIDEGWRLLDFKNHKVGEFIEKGYRTARRHTGAYITITQNIVDFDSD
                     KASSAARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFLPLQRDMIGKFGAAKDQWFSS
                     FLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRKEGLSIHEAVWQLAWKKSGP
                     EMASLEAWLEEHEKYRSVA"
     gene            complement(8716..8937)
                     /gene="traR"
                     /locus_tag="RH288_003551"
     CDS             complement(8716..8937)
                     /gene="traR"
                     /locus_tag="RH288_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraR"
                     /protein_id="HDV4032570.1"
                     /translation="MSDEADEAYSVTEQLTMTGINRIRQKINAHGIPVYLCEACGNPI
                     PEARRKIFPGVTLCVECQAYQERQRKHYA"
     gene            complement(9072..9587)
                     /gene="traV"
                     /locus_tag="RH288_003552"
     CDS             complement(9072..9587)
                     /gene="traV"
                     /locus_tag="RH288_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system lipoprotein
                     TraV"
                     /protein_id="HDV4032571.1"
                     /translation="MKQISFFIPLLGTLLLSGCAGTSTEFECNATTSDTCMTMEQANE
                     KAKKLEQSSEAKPVAASLPRLAEGNFRTMPVQTVTATTPSGSRPAVTAHPEQKLLAPR
                     PLFTAAREVKTVVPVSSVTPVTPPRPLRTGEQTAALWIAPYIDNQDVYHQPSSVFFVI
                     KPSAWGKPRIN"
     gene            complement(9584..9835)
                     /gene="trbG"
                     /locus_tag="RH288_003553"
     CDS             complement(9584..9835)
                     /gene="trbG"
                     /locus_tag="RH288_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbG"
                     /protein_id="HDV4032572.1"
                     /translation="MNKLVSDGSVKKINYPVLYESGITPPLCEVSAPEPDAGGKRIVA
                     YVYKSSRSTVFENPDIVKTCTVRDLKKDFVNCDEKGEGQ"
     gene            complement(9847..10077)
                     /locus_tag="RH288_003554"
     CDS             complement(9847..10077)
                     /locus_tag="RH288_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbD"
                     /protein_id="HDV4032573.1"
                     /translation="MTEQTETTEIKMNMRNINVITALSVPGKTVSDDFMHAVLSNCAT
                     RIVLPAPEKFGSESLPDNFNMTAVGVMKNSEI"
     gene            complement(10031..10621)
                     /locus_tag="RH288_003555"
     CDS             complement(10031..10621)
                     /locus_tag="RH288_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraP"
                     /protein_id="HDV4032574.1"
                     /translation="MANNMSSRQACHAARYVVARVLRGLFWCLKYTVILPLATMALMA
                     LFVLWKDNTTPGKLLVKEINFVRQTAPAGQFPVSECWFSSSDSSGRSEIQDICHYRAA
                     DAADYVRETDRSLMQLVTALWATLALMYVSLAAITGKYPVRPGKMKCIRVVTADEHLK
                     EVYTEDASLPGKIRKCPVYLPDDRTNRNNGDKNEHA"
     gene            complement(10611..12038)
                     /locus_tag="RH288_003556"
     CDS             complement(10611..12038)
                     /locus_tag="RH288_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraB"
                     /protein_id="HDV4032575.1"
                     /translation="MASINTIVKRKQYLWLGIVVVGTASAIGGALYLSDVDMSGNGET
                     VAEQEPVPDMTGVVDTTFDDKVRQHATTEMQVTAAQMQKQYEEIRRELDVLNKQRGDD
                     QRRIEKLGQDNAALAEQVKALGANPVTATGEPVPQMPASPPGPEGEPQPGNTPVSFPP
                     QGSVAVPPPTAFYPGNGVTPPPQVTYQSVPVPNRIQRKVFTRNEGKQGPSLPYIPSGS
                     FAKAMLIEGADANASVTGNESTVPMQLRITGLVEMPNSKTYDATGCFVGLEAWGDVSS
                     ERAIVRTRNISCLKDGKTIDMPIKGHVSFRGKNGIKGEVVMRNGKILGWAWGAGFVDG
                     IGQGMERASQPAVGLGATAAYGAGDVLKMGIGGGASKAAQTLSDYYIKRAEQYHPVIP
                     IGAGNEVTVVFQDGFQLKTVEEMALERTQSRAEEDNPESPVPVPPSAESHLNGFNTDQ
                     MLKQLGNLNPQQFMSGSQGGGNDGK"
     gene            complement(12038..12742)
                     /gene="traK"
                     /locus_tag="RH288_003557"
     CDS             complement(12038..12742)
                     /gene="traK"
                     /locus_tag="RH288_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HDV4032576.1"
                     /translation="MFGSLFFSCSVMAANGTLAPTVVPMVNGGQASIAISNTSPNLFT
                     VPGDRIIAVNSLDGALTNNEQTASGGVVVATVNKKPFTFILETERGLNLSIQAVPREG
                     AGRTIQLVSDLRGTGEEAGAWETSTPYESLLVTISQAVRGGKLPAGWYQVPVTKETLQ
                     APAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPASQLL
                     AGARMDVYVIRDGEGN"
     gene            complement(12753..13319)
                     /gene="traE"
                     /locus_tag="RH288_003558"
     CDS             complement(12753..13319)
                     /gene="traE"
                     /locus_tag="RH288_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HDV4032577.1"
                     /translation="MEHGARLSTSRVMAIAFIFMSVLIVLSLSVNVIQGVNNYRLQNE
                     QRTAVTPMAFNAPFAVSQNSADASYLQQMALSFIALRLNVSSETVDASHQALLQYIRP
                     GAQNQMKVILAEEAKRIKNDNVNSAFFQTSVRVWPQYGRVEIRGVLKTWIGDSKPFTD
                     IKHYILILKRENGVTWLDNFGETDDEKK"
     gene            complement(13341..13652)
                     /gene="traL"
                     /locus_tag="RH288_003559"
     CDS             complement(13341..13652)
                     /gene="traL"
                     /locus_tag="RH288_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HDV4032578.1"
                     /translation="MSGDENKLKKYRFPETLTNQSRWFGLPLDELIPAAICIGWGITT
                     SKYLFGIGAAVLVYFGIKKLKKGRGSSWLRDLIYWYMPTALLRGIFHNVPDSCFRQWI
                     K"
     gene            complement(13667..14032)
                     /gene="traA"
                     /locus_tag="RH288_003560"
     CDS             complement(13667..14032)
                     /gene="traA"
                     /locus_tag="RH288_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system pilin TraA"
                     /protein_id="HDV4032579.1"
                     /translation="MNAVLSVQGASAPVKKKSFFSKFTRLNMLRLARAVIPAAVLMMF
                     FPQLAMAAGSSGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVKFL
                     AGFAIISVFIAVGMAVVGL"
     gene            complement(14065..14460)
                     /gene="traY"
                     /locus_tag="RH288_003561"
     CDS             complement(14065..14460)
                     /gene="traY"
                     /locus_tag="RH288_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer relaxosome protein TraY"
                     /protein_id="HDV4032580.1"
                     /translation="MKRFGTRSATGKMVKLKLPVDVESLLIEASNRSGRSRSFEAVIR
                     LKDHLHRYPKFNRAGNIYGKSLVKYLTMRLDDETNQLLIAAKNRSGWCKTDEAADRVI
                     DHLIKFPDFYNSEIFREADKEEDITFNTL"
BASE COUNT         3346 a         4086 c         3485 g         3606 t
ORIGIN      
        1 cagaagccac tggattgcgg tatggtttat catatggtct tcagtaatca acctcattat
       61 tttgtatggt ttttatgacc gttttatatg acttagcctg tcataagccc ccttataaaa
      121 aaccacatca ctccggacca taccgatgac aacacaatac agataaatat tcttctgaac
      181 ctgtcgaagc tcgtaacgtc cggtaatgcg gccgcaacta ttgaaacaac cagtgctgcg
      241 ccctgactca taattgcacc acacagaaac cagagactgg cggtaagcac atataaacac
      301 gcgatattaa taacaaggaa aaccagtgag ctcaggagaa acattttcct gtcattacgc
      361 tcagaaaaga aataaccggc aataatgaca aatattaaca gaacaacacc tgtaaacatt
      421 ttcaaataat cttcactcat aaatcaaatc cgcgattaaa aattgggttt aaaatcttca
      481 gaaacgttca ggaactgttt tgccaggtcg tcctgcgaaa taaagccgta tgataacggg
      541 cgaatactgc cctgtttcgg gtcaaccagc atcatggccg ggaaatattt cacgccgagg
      601 cgctgcgcct gcccctggtc agtccgggaa tccggcaaca gcggattaat cacgccatcc
      661 acggaaacgg gaataacact cagaccatac gtatcccgga agccattaat gacctgcgcc
      721 agttgcccgt cgatggggtc ctgcccccgg taaaaaaaca tgatgccgta gtgttcagcc
      781 agtttcgcaa tggcctgtcg ctgctgcgcc tggtctgctg ccagctggtt ccgtaccgtg
      841 ccgttgtaat ggctgtactg caggttatag tccagttcag gatgtgccag catggccttt
      901 ctggcgctca tggtgaaaag cccggcctgc tgagtccagt aattttgcag ccggaaatat
      961 ttcacaaaat tatccacgcc gggatacaga atggcttcgt acagcgcccg ctttgttgcc
     1021 gtctgcagtg cggccagttt ctgcataata tccggttcct gacggggggc tgcaggtaca
     1081 ggtttatttt ctttttcctt cggatttatt ttctcgttat accactgcca gcctgcatct
     1141 tttcctgacg ccggaaaaat aaagcagcag agtaacagtg gcagtaatgc tttattcatc
     1201 ttcattcctt tcatcacttt ttctttcatc aggtttctgc aggtcagtca gggcagaaaa
     1261 acaaaaatac agaataaaca ggagcacacc ggagtaaagg ataacgaaag cagcggcaag
     1321 catcccgtct gccgtggttt cttttaccgt atcccacgac cagataatta ccggagaaat
     1381 gacaatcgct gtaatcaaaa gccggataag aaaatcaata aaacggttcg acgtgaatat
     1441 gactttcatc atttcccccg gttatttccc ataccttact gtcctgcctg tttcagctgg
     1501 tcagcaatct gctctttcac tttctgcgtc agaacgccac tgtccgggat tttctggtta
     1561 ttcatcaggt cttcgtagaa gttagtgaaa tccagtctgt tgaactgaat tttctgcagc
     1621 tcatcaaccg taatcccccg acagtcagga tgcttcgcac taccaaaact gatacgcaac
     1681 tgaccgttgc gcccctgctg ctggactatc tgcgccagct tcgaatcaaa ctgacagtag
     1741 ctgcgttttt tctccagaca gacacccagc actttcttcg aacagaactc cccgacgctg
     1801 acggtcagtt tgtttgattt tgctttagcc agggcctttt catcactgct gcatttggcc
     1861 agcccgatat cctgtcccca gccgctgtcc ttacagcagt tgctgtatcc ggctgcagcc
     1921 ttcttacaaa atttcgcctg accggtgaaa gcacggacat cccccccgtt cagcgccgca
     1981 acatccttac ctgctgcggc cagtgccgcc agctgagaaa cggcttcggc aaaatcatta
     2041 ctctgcccgc tctgagcctt atcgcattcg ccatcgagac agaatacgtc tcccccacag
     2101 accatcactt tcccggatgt ttttgactca caggagtacg tggcatattc atgcagacag
     2161 gcaccttctt cggagtaaaa ggcacactgg tgtgacacca gggtacaggc aggattgtcg
     2221 gtgtaggtct gacaggttcc cttgtctgct gactgcgtga catacgtgtc ccggtatgcc
     2281 cagcagctct ggtacatgct gtatgactga ccgtctttca ccagcgtcct gttcccgcca
     2341 gcctccgtac attctgtttt tgtcagtttc cccagctcct tgctgaacgg gcagctttca
     2401 gaccagacaa catacggggt gtacgaggct ttttttaccc tgacaaccag acgcagcttc
     2461 attgccgtat gacgtttgaa ttttgtattc ccgacccgga cggggtgaga tgacgtaaaa
     2521 gccacaccgg cagtcagtgt tttctgtact ggtgtaaatg aggcatctgc tgagtatttg
     2581 gcattccagc tcagtggggt tcccagtact gtaattgtca taggtacact cttctgcaag
     2641 taagtacgac tccagctgta atgcgcatcg acaatttcac cggtaacggg agaggtaatg
     2701 gagacaacat actgaccatt cacttcacgt gcaggtagct gactcatttc atactccagc
     2761 gtccgggttt cccatgtggt actcccctgc agctccatac gggcagttcg tgtgcagtac
     2821 tgctccacct gtaaatcccg ctcacaggtg taattcgtgt attcactcct gctaatctcc
     2881 tgcgcactgc actgctgccc ggtgtttccc acaatgctgt cagcccggtt caccacatcc
     2941 ctgccggtct ggataaacgg tgcatccggt gaaagaatgt ctttcggctt gttcatgaat
     3001 gactctgtaa tggtttttcc ggtttcaccg gtcgcccatt ccgtggtgcc gtcatttttc
     3061 aggccgccat ccccgccggc agtcacgcca ccgtaatatt ttgtctcgtc cggattcgcg
     3121 ttatagccgg ggatactctc ctgtggctta aagccctgaa tactgctgct tccctgccct
     3181 ttgatctggt gagcaaaatc agaaccggcc cggtaatcac tgttgctgtc agcctgtgcc
     3241 atgccggcaa ccagagccag tatcagaggt aaaatacgtt tcatttcccg gaatctcctt
     3301 tccctgccag taaatcatga gccacctgcc ggcagtcacc cgtggcggcc actttctcca
     3361 gcgcctggcc gacccgcagg tttccccgga tgatgtcgta tccctgactg cagaacacca
     3421 ccagtgccgg tacagtgcga atgccgtact gtgaaaacag cgtcgggtcg atctgaacac
     3481 catcagtcgc gccgtctttc accagggaca acacagcttc agcggtggtc ttcaggtcat
     3541 tgttcaccat gccccgcagt gtggccggaa taccgtagtg ccgggtttcg cccagcattc
     3601 gtttcagccc ctcttcggga atggaaaacg acacaaaata cagagcaccc tgccggggtt
     3661 tcccgtcctg cgaagcctgc tgtttacgaa ccagctcatc caggaaatgg ttatctgaac
     3721 gctgaagggg gttttccagc acctgtttct ccgcccaggc tttcagctga tggtcaggtt
     3781 tttcacgcag ttgtctgctt aaattttcct gctgcttcag gaactggcgg ttttcaggag
     3841 tgttcacgtt ttctgacgcc ataaccgccc cgttcagcat catcagcagt gctgccagag
     3901 atttcatact cagcttcatc attcacctca caggaagaca cagttacgtt tacgccacat
     3961 caggtagccg aagtttttct ttgtgttggg cggatttttc ccggtttccc agcgggtcac
     4021 gctgcgcccg aacgggtggc actgcccgct gtccggatac atattcacca tctggtaacg
     4081 ccagcgttct ttgggcagga ttggggacgg atattcatta cagacggcgt tattttttcc
     4141 gatggtttcc ataatcatgc cctgacggtg cagcttgaac gccatgcgtt cactgaccag
     4201 cagggaggac tgcaacggac tggactcatt actcacccag ccattgaacg ggtacatact
     4261 tccctgcgaa ccggcacacc agaacagaac atcgagaggc atattaaagg cgctggcaat
     4321 cgcatctgct gcgcaggctc cctgtgctat cggattggca aagatgacag cttccggatt
     4381 gagaatggtg gtcaggctgc tgtccgtcca ggtggggtcg atttcagaaa gataagcgat
     4441 atccaggtca ccaccttcca gacagcccag cgatgtgatg atgttcagcc agtacgtcag
     4501 cgggtatttg taccagtgaa cgtgatagaa cgccccattt acctgcttct catccttttt
     4561 cgccgttccc tgtgccgttt taccaaaagc cggcaggctg aagcccaggt tcaccatgca
     4621 tcccggtgac cgggtgacgt ccgtcaacgc catcggctcc cagtaaccaa tggccagccc
     4681 gatacgcctg aacagcggcg gcagtgccgg acaaatctga atgggcatcg acgggttcgc
     4741 cgtgtcgggg accttcccct gactgacttt gatactgccc agcgagagcg ggaaaataca
     4801 gctccagcag atatctgtga tcgggtttac aaaacgcccc tcacaggcag aatccgcaga
     4861 cgccgcaggg acatgaccgg cgaaaaggaa taacatcagc agccacagcc ttcgcttcat
     4921 tttctgccct cctctgccgg aataaattcc accttcagga agcgatcgcc gggaacggcg
     4981 ctcacccgtg ccgggacctg atcaatgccg aggcgctggc agagcacacc gttctggtca
     5041 aagtaaacac ggctgtccag agacttctgc atctccggga tactgccctg cacgaggata
     5101 attttgctct ccagtgtggg cggcgtctgg cgtttcatcc aggccacctg cgccggatca
     5161 tcgccattga tgaaatacag cgtctggtta aaaggaacat actgcagcgg attcatcact
     5221 tcaccctgac gggcaaacac ccgcccttcg ttatcccgga tatccgcagc cagtctgacg
     5281 gacgggtcaa acaaccggct gccgtatttc tccgtgcgtc cgataccggg cacggcaggg
     5341 ggccgcagac tgttgcggat cacccgctcc ttaaaggcat ccattttccg gcccatctca
     5401 ccggactgct ccagtgccgt caggcgctgc atgatcaccg tcagcatgtc cggctccttt
     5461 accggccaca gatcgcccca ggtaccaaga tcggcggcgg ccacactctg cccccatatc
     5521 agcagggcaa tcagcccccg gcatctcatg gttccgccct cattcgccgg gcaatatcct
     5581 gctggatttc ccgggtgata tccggtgccc cctgtaccac agcaggcgac accagaatga
     5641 ccgcgtggtg tttctgctgc cacgcctgca ggctggcttc cagtgccgtg ttaaaacgcg
     5701 ctgaaagggc ttttgactgc gcttctgaca gttgtttctg actggctctg tcaaaaaacg
     5761 catccacggt ctgtttcatg ttgaaggcga cagtcaccgg tgcgttcagt ctgacaatgc
     5821 cgtaactgac ggctgcgttc agtaacacca ttgccaggca tcccggcacc gtccaccacc
     5881 agtggctgcg tcgttctgcc atgacgtcgg cgggtttctg cgttgaactc atgccacact
     5941 cctgtatttc tcatgttctt ccagccaggc ttccagcgaa gccatttccg gccctgactt
     6001 cttccacgcc agctgccaca ctgcctcatg aatactcagc ccctctttac gcttctgctg
     6061 cacaaactca aaatccgggc cgtcagagct gtacatggcg cggcttaacg ggtccacaaa
     6121 cagacggtgc caggaggaat ggttttccac ctgcagcagg aaggaactga accactggtc
     6181 tttggccgca ccaaacttac caatcatgtc gcgctgcagt ggcaggaact ggtccggata
     6241 cagttggttg tatttcgcga actccttcgc actctgtttg aggataattt tgtaggagga
     6301 gttaccccat gccgcgcggg cagcactgga ggccttatca gagtcaaagt cgacgatgtt
     6361 ctgtgtgatg gtgatatagg caccggtatg acggcgggcc gtacggtagc ctttctcaat
     6421 aaattcaccg accttgtgat ttttgaagtc cagcagacgc cagccttcat caataacgtt
     6481 cagtttcttg aggttacgcg gcgtgcggta catcctgttc tcgatgtaga taatcaggga
     6541 gaacatcacc gcaaccagca gtgacggacg gtcttccagt ccgcccagct ccagcaccac
     6601 catttttgcg tcatcccgca gggacggctc atcagagtta aaatactggc cgtaagtgcc
     6661 gttggcagtg tactggtcaa gcagcacaat catttcgtcc agacggctgc ggatagtcgg
     6721 tgactcggca tactgctcgc tgtcactggc gtttttcagg aaatccacca cgtcatcaat
     6781 acgtgctctg ttctctttgg ccagccagga ggctctgacc gcctgcaaca gcagaccttc
     6841 atgcacttca tccaggttac cgttggggct ggccatcact gacaactggt cacggacacg
     6901 ctccgctgac tggtcaatat cggtgatgtt cgcaaacggg ttaaaacgca gggtttcacc
     6961 gtccagatac accccgccca tgttctcaca cagggacttg tatccatccc ccatgtcgaa
     7021 caccacggca aagcctccgg agtccagcac gctgcggata agtggctgta tcagcccggt
     7081 tttaccggcc ccggaggtgc cacagaccgc catgttgtag ttggtgttat tcatcccccg
     7141 gaagaaaata tcgataaacg ccagctggtt acggtaggtg ggtgccagca gacctgccgg
     7201 tgtcaggggg ttatccgcca ctaacggcat caggttggca acattaaagc tctctgcgcg
     7261 ctgaaccact ccggcctctt tcaactgttt aaacagccct ttcccggcca taaagggcag
     7321 gcaggtcagg aaattgcgca tgtggttaaa gcgcggtgaa atcagctcaa aaccgttttt
     7381 acgaaagctg ttcaggatgt cctgctccac ttccagcgcc gtttcattat tgtccttgca
     7441 gaatgctgtg atgttgagga agtaggacac cacggaggac tgaccggagc ccagccgctg
     7501 acgcagttcc ccccactcct tcgcctcttt ctccacggac ggaaaccatt tggcatagga
     7561 ggtcttcgac tttttctcca ggtccatgta cttcaggttg gcttcgctgt gggttttcac
     7621 ctggtcttcc accaccagag tcagcgtcag gatgaacgga caggagatgg acagttccgg
     7681 gttcagcagg ttgctgtagt tgtcggccac gttccacagg aaggcgattt ccgggttacg
     7741 ggccagatgg aaattcagga tgcgggccgt gctgttcctg ccgttctcac gcaggcccag
     7801 cgtcaggtaa tcagcccgga ctttcagatc aaaactgtcc tccacacact gataattcag
     7861 atcagaatac gggtccagct gacgtctttt cgggtacagg gagtccgggt tatggttaat
     7921 catctccccg acaatatcga taaaggcctg tgcatccacc gtctgtgtgg tgatactggc
     7981 cccctgtaac gacgcccgga tgattttcac caggttttcc atttccagaa tgtcggcccg
     8041 gctttttttc ttcgaaggag aacagtacga gataaacacc cggtaatggc gcagggtcag
     8101 gggcagattc atcccctccg gcagcggaaa ctgtgtcgct gccgctttca tataataggc
     8161 ccgggtaatg gcgttaaacc gttcagcctg ttcacctgac caggagaact cacgcagccc
     8221 gtattcaatc ctgtcaccaa ccagctgact ggacatcaga tggatacaca acggaatacc
     8281 gcgcggcagt ttggtgcgca gcatgtgatc gagggcctcc acaatggact cattcgcccc
     8341 attgatgggg atggcttcca gcataaagcc catcgtggtg tcattcatga acagaccgga
     8401 ttcctggttg taatcacggt acggcagcag acggctgaac tgcgggaagc tcatttcgcc
     8461 cagaacttca ttggcctttg cggattcgtc aggcagtttc agtgctgtga cgagggagtt
     8521 aaccgcctga gtgacggcct caagtgggtt attcacatga attccttagt tgaaaaataa
     8581 agcgagaaat gcggtagcca tgaagggaat acctgtaatt aacgcgccat ttcccggcgc
     8641 atatacaaag atttctgttt tctgaatatc cactcatgtt catccggaat taaatcacta
     8701 tgttctgcga ctgacttatg cataatgttt tctctgtctt tcctgatacg cctgacattc
     8761 aacgcacaac gtcacaccgg gaaatatttt ccgccgggct tccggaatag gatttccgca
     8821 tgcttcacag agataaacag gaataccatg agcatttatt ttctggcgta tccggtttat
     8881 tcctgtcatg gtcagttgtt ctgtcactga atatgcttca tcggcttcat cactcacgga
     8941 atattcctcc cgacatgttc tgacacgcta ccgcccatcc cttttcacgc acagggcact
     9001 cgttttacag gcagattttg aatacagaaa gcccgccggc attgccggct gatatacaac
     9061 ttcagggcca gttaattaat acgtggtttt ccccacgcag acggtttaat aacaaaaaac
     9121 acgctggatg gctgatgata aacatcctgg ttatcaatat aaggcgctat ccataatgct
     9181 gccgtctgct cacccgttct tagcggacga ggaggtgtta ccggcgtaac tgaactgacc
     9241 ggaacaaccg ttttcacttc ccgggcagcg gtaaacagcg ggcgaggtgc cagcagtttc
     9301 tgctccggat gtgctgtcac cgcaggtctg ctgccggacg gagtggtcgc ggtgacggtc
     9361 tgcaccggca ttgtccggaa gttcccttca gccaggcgcg gcagtgatgc cgcaaccggc
     9421 tttgcttctg aggactgctc cagttttttg gccttctcat tggcctgctc catcgtcata
     9481 caggtatcgg atgtggtggc gttacactca aattccgtac tggttccggc acagccggaa
     9541 agtaataagg tccccagcag aggaataaag aaagaaatct gtttcattgt ccctcacctt
     9601 tctcatcgca gttcacaaaa tccttcttca aatccctgac cgtacaggtt tttacaatgt
     9661 caggattttc aaaaaccgta ctccgtgatg atttataaac atatgccaca atgcgtttcc
     9721 cacccgcatc aggttctggt gcactgactt cacataacgg aggtgttatt ccggactcat
     9781 acagcaccgg ataatttatt tttttgacgc tgccatcaga aaccagctta ttcatcgaag
     9841 ggttccttat atttctgaat tcttcatcac accgacagca gtcatattaa aattgtccgg
     9901 caatgactca gaaccgaatt tctccggtgc aggaagtacg attcttgtgg cgcagttact
     9961 gagaacagca tgcataaaat catctgacac ggttttaccc ggcacagaga gggctgtaat
    10021 aacattaata ttacgcatgt tcatttttat ctccgttgtt tctgtttgtt ctgtcatcag
    10081 gaagataaac agggcatttc ctgatttttc ccggcaggga agcgtcttcc gtataaactt
    10141 ccttcagatg ttcatctgcg gttaccaccc ggatacattt catttttccg ggtcgcaccg
    10201 gatatttccc ggtgatcgct gccagcgaga catacatcag tgccagtgtt gcccataatg
    10261 cggtgaccag ttgcatcagt gaccggtcag tctccctgac ataatctgca gcatcagccg
    10321 cgcggtaatg gcagatatcc tgtatttctg atctgcctga agaatcagag gaagaaaacc
    10381 agcattcact gaccgggaac tgtccggcag gtgctgtttg tcttacgaag ttaatctcct
    10441 taaccagtaa tttccccggc gtggtgttgt ccttccataa aacaaacaga gccatcaggg
    10501 ccattgtggc cagtggcaga atgacggtgt acttcagaca ccagaacagt cctcgcagaa
    10561 cccgggcgac aacataccgg gcggcatggc acgcctgacg ggacgacata ttatttgcca
    10621 tcgttgcccc ctccctggct gccggacata aactgctgcg gattcaggtt gcccagctgc
    10681 ttcagcatct ggtcagtatt aaagccgtta agatgacttt cagccgatgg cggaacagga
    10741 accggacttt ccggattgtc ttcttccgct ctgctctgcg tgcgttccag cgccatctct
    10801 tccacggttt tcagctggaa gccgtcctgg aacaccacgg tcacttcgtt gcccgcacca
    10861 atcggtatca ccgggtgata ctgttcggca cgtttgatgt agtagtcact gagcgtctgt
    10921 gcggctttcg atgcgccgcc accgataccc attttcagga catcaccagc cccgtaagcg
    10981 gctgtggcac ccagcccgac agccggctgg gaggcgcgct ccattccctg accgataccg
    11041 tcaacaaatc ccgcgcccca tgcccagccg aggattttgc cgttacgcat caccacttcg
    11101 cccttgatac cgtttttacc ccggaagctg acatgcccct taatcggcat atcaatagtt
    11161 ttgccgtcct tcaggcaact gatattgcgg gtgcgtacaa tggcacgctc actggacaca
    11221 tccccccagg cttccagacc cacaaaacat cccgttgcgt catacgtctt gctgttcggc
    11281 atttccacca ggccggtgat acgcagctgc atcggcaccg tggattcatt accggtgaca
    11341 gaggcattgg catccgcccc ttcaatcagc atggctttcg caaaacttcc tgacggaatg
    11401 tacggcagtg atggtccctg ttttccctca ttacgggtaa acaccttacg ctgtatccgg
    11461 ttaggcaccg gcacagactg gtacgtcacc tgtggtggtg gcgtgacacc attcccggga
    11521 taaaacgccg tcggcggtgg aacagcaacg ctgccctgcg gcgggaagga tacgggggtg
    11581 tttcctggct gtggttcgcc ttccgggccg ggcggtgagg caggcatctg cggtacaggc
    11641 tcaccggtcg ccgtgacggg attagcaccc agggctttta cctgctctgc cagggcggca
    11701 ttgtcctgtc ccaacttttc aatacgacgc tggtcatcac cgcgctgttt gttcagaaca
    11761 tccagctcac gacggatttc ctcatactgc ttctgcatct gcgctgccgt cacctgcatc
    11821 tcggtggtgg catgctgacg caccttgtca tcaaaggtcg tatccaccac accggtcata
    11881 tccggcacag gctcctgttc agccacggtt tcaccgttac cggacatgtc cacatcagac
    11941 agatacagtg ccccaccaat cgcggaggct gtaccgacaa ccacaatccc cagccacagg
    12001 tactgcttgc gtttcacaat ggtattgata ctggccatca gttgccctcc ccgtcacgga
    12061 tgacatacac atccatgcgc gcacctgcca gtaactggct ggcaggctgg ctgaacatca
    12121 cggcacgggt tcccggctgc cagaagtcac tttcccggat attcagggca gacagcgttt
    12181 tattttccac ggcaaagcgg accatcttca ggtgattccc cgtccatacg gcatctgcca
    12241 ctgaagacag ccccgccggg gcctgcaggg tttcctttgt cactgggacc tgataccagc
    12301 ctgcgggtaa ttttccgcca cggacggcct ggctgatggt cacaagcagg gattcgtaag
    12361 gcgtggacgt ttcccacgca ccggcttctt ctccggttcc gcgcaggtca ctgaccagct
    12421 gaatggtacg ccccgcgcct tcacggggaa cagcctgaat ggaaagattc agaccacgtt
    12481 ctgtttccag aatgaacgta aagggctttt tgttgacggt ggcaaccacc acaccgccgg
    12541 aggcggtctg ctcattattg gtcagggcac catccagact gttcacggcg ataatccggt
    12601 caccgggaac ggtaaacaga ttcgggctgg tattgctgat ggcaatactg gcctgaccac
    12661 cgttcaccat tggcaccacg gtgggggcca gcgtaccgtt tgcggccatc acgctgcagg
    12721 aaaaaaacag gctgccgaat attattgccg tattattttt tctcatcgtc tgtttccccg
    12781 aaattatcca gccaggtcac cccgttttcc cgcttcagaa taaggatgta atgtttgata
    12841 tcagtgaaag gttttgaatc accaatccag gttttaagca cacctcgaat ttccacacgg
    12901 ccatactgag gccagacacg aacactggtc tggaaaaagg ctgagttcac gttatcgttt
    12961 ttaatacgct tcgcttcttc agccagaata actttcatct ggttctgtgc gcccgggcgg
    13021 atatattgca gaagcgcctg atgtgaggca tcgacggttt ctgatgaaac attcagacgg
    13081 agggcaataa atgacagcgc catctgctgt aaataagagg cgtcggcact gttctgtgac
    13141 acggcaaagg gggcattaaa tgccattggc gtcacggcag tgcgttgctc attctgaaga
    13201 cggtagttat tcaccccctg aatgacgtta acagagaggc tgagaacaat aagcactgac
    13261 ataaatataa aggcgatggc cattacacga ctggtactta aacgggcacc gtgttccata
    13321 taacaatcct ggtatcagtt ctatttaatc cactgccgga aacacgaatc gggaacatta
    13381 tgaaaaatac cgcgcagcag ggctgttggc atataccagt aaatcaggtc acgtaaccag
    13441 gaactgcccc gccctttttt cagtttttta atcccgaaat aaaccagaac cgctgcacca
    13501 ataccgaaca gatatttcga tgttgtgata ccccagccaa tacagattgc tgcggggatc
    13561 agttcatcca gtggcaggcc aaaccagcgg ctctggttgg tcagtgtttc cgggaaacga
    13621 tatttcttaa gtttattctc gtctcccgac atcgttttat ttcctgtcag aggccaacga
    13681 cggccatacc cacagcaata aatacagaga tgatggcaaa accggccagg aacttgacgt
    13741 ttttggtcat catgtacatg acagcaccga ccagaacttc agccagaaca acccatttaa
    13801 caacactgga gtccttaccg aaggtcgcct taaccgtggt gttaccgctt gccatcaggt
    13861 cctgaccact gctgccggcg gccatcgcca gctgcgggaa gaacatcatc agaacagcag
    13921 ccgggatcac tgcgcgagcc aggcgaagca tattcagacg agtgaattta gaaaaaaacg
    13981 acttcttttt gacgggcgca gaagcaccct gaacacttaa aacagcattc ataagttacc
    14041 tcaatttcgg ataaatgaat aaaactagag tgtattaaat gttatatctt cctctttatc
    14101 tgcctccctg aatatctccg agttataaaa atcaggaaac ttgatcaaat gatcaataac
    14161 tctgtctgca gcctcatctg ttttacacca tccactacga tttttggctg caataagtag
    14221 ctggttagtt tcatcatcca gacgcattgt cagatactta accagcgact taccatagat
    14281 attccctgcc ctgttaaact ttggatagcg gtgaagatga tctttaagtc ttattactgc
    14341 ctcaaacgat cgacttcttc cgcttctgtt acttgcctca attaatagac tttccacatc
    14401 tacaggtaat tttagtttta ccatcttacc tgttgcagaa cgtgtaccaa atcttttcaa
    14461 taacacctcc cgctgtttat cttctggtta ccacttatgt ttacagaata atcagaaaag
    14521 gta
//
LOCUS       DAPHKZ010000113        14428 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.113, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000113 DAPHKZ010000000
VERSION     DAPHKZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14428
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.113"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..867
                     /locus_tag="RH288_003562"
     CDS             <1..867
                     /locus_tag="RH288_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HDV4032581.1"
                     /translation="PSQTVEQTVRHIYQNYKSDATAPYFGETGERAITSARIQQALTL
                     NDNLTLPGNIGWLDYDPVCDCQDFGDLVLESVAITQTDADHADAVVRFRIFKDDKEKT
                     TQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLAALASLQKEQPEAFVAELFEH
                     IADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDMQIERQFIYDNPICFGEESLF
                     SRVDEIRVLEKTADSARIHVRFTLTNGNNEEQELVLQRREGKWEIADFIRPNSGSLLK
                     QIEAKTAARLKQ"
     gene            918..1175
                     /gene="yqhH"
                     /locus_tag="RH288_003563"
     CDS             918..1175
                     /gene="yqhH"
                     /locus_tag="RH288_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YqhH"
                     /protein_id="HDV4032582.1"
                     /translation="MKTIFTVGAVVLATCLLSGCVNEQKVNQLASNVQTLNAKIARLE
                     QDMKALRPQIYAAKSEANRANTRLDAQDYFDCLRCLRMYAE"
     gene            complement(1218..3437)
                     /locus_tag="RH288_003564"
     CDS             complement(1218..3437)
                     /locus_tag="RH288_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDV4032583.1"
                     /translation="MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWSSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIR
                     DVRNTAIIVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKA
                     VTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICPHMDTNHEPTINLYRRARDLKGIKKILIASGVRYDIAVEDPRYI
                     KELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYK
                     SEDVFVPKGDKQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIE
                     EMREARRQNRNTRPALTKHTPMATQRQTPATAKKASSTQSRPVNAGAKKRPKAAVGR"
     gene            complement(3548..4960)
                     /gene="ftsP"
                     /locus_tag="RH288_003565"
     CDS             complement(3548..4960)
                     /gene="ftsP"
                     /locus_tag="RH288_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HDV4032584.1"
                     /translation="MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRR
                     GQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMT
                     VAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMNDGRPLHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     SLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADE
                     PQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNS
                     QTLEMADRGSIGQLLVNPVP"
     gene            complement(5035..5772)
                     /gene="plsC"
                     /locus_tag="RH288_003566"
                     /gene_synonym="parF"
     CDS             complement(5035..5772)
                     /gene="plsC"
                     /locus_tag="RH288_003566"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HDV4032585.1"
                     /translation="MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPTDAESYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELA
                     AHCRSIMEQKIAELDKEVAEREAAGKV"
     gene            complement(6006..8264)
                     /gene="parC"
                     /locus_tag="RH288_003567"
     CDS             complement(6006..8264)
                     /gene="parC"
                     /locus_tag="RH288_003567"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDV4032586.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTE
                     AEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGI
                     LASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITL
                     PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARG
                     EDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEID
                     SPRRASSGDSEE"
     gene            complement(8402..10009)
                     /locus_tag="RH288_003568"
     CDS             complement(8402..10009)
                     /locus_tag="RH288_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV4032587.1"
                     /translation="MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPG
                     TLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQ
                     WSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKAT
                     DDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDQWV
                     VNEKITARKNPKYRDAQHTVLQQVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIE
                     KSLPGELRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATT
                     LTPPEVKGFSATTFDELQKPMSERVAMAKALLKQAGYDASHPLRFELFYNKYDLHEKT
                     AIALSSEWKKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASSFLNTLKS
                     DSEENVGHWKNAQYDALLNQATQITDATKRNALYQQAEVIINQQAPLIPIYYQPLIKL
                     LKPYVGGFPLHNPQDYVYSKELYIKAH"
     gene            complement(10142..10537)
                     /gene="mqsA"
                     /locus_tag="RH288_003569"
     CDS             complement(10142..10537)
                     /gene="mqsA"
                     /locus_tag="RH288_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MqsA"
                     /protein_id="HDV4032588.1"
                     /translation="MKCPVCHQGEMVSGIKDIPYTFRGRKTVLKGIHGLYCVHCEESI
                     MNKEESDAFMAQVKAFRASVNAETVAPEFIVKVRKKLSLTQKEASEIFGGGVNAFSRY
                     EKGNAQPHPSTIKLLRVLDKHPELLNEIR"
     gene            complement(10539..10835)
                     /gene="mqsR"
                     /locus_tag="RH288_003570"
     CDS             complement(10539..10835)
                     /gene="mqsR"
                     /locus_tag="RH288_003570"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin MqsR"
                     /protein_id="HDV4032589.1"
                     /translation="MEKRTPHTRLSQVKKLVNAGQVRTTRSALLNADELGLDFDGMCN
                     VIIGLSESDFYKSMTTYSDHTIWQDVYRPRLVTGQVYLKITVIHDVLIVSFKEK"
     gene            complement(11040..11522)
                     /locus_tag="RH288_003571"
     CDS             complement(11040..11522)
                     /locus_tag="RH288_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV4032590.1"
                     /translation="MTNLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKET
                     GLSPVNQSQTFGVAWDDPATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVA
                     RHVGELDDISHTVWGIIRHWLPASGEKMRKAPILFHYTNLAEGVTEQRLETDVYVPLA
                     "
     gene            complement(11575..11967)
                     /gene="ygiW"
                     /locus_tag="RH288_003572"
     CDS             complement(11575..11967)
                     /gene="ygiW"
                     /locus_tag="RH288_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB fold stress tolerance protein YgiW"
                     /protein_id="HDV4032591.1"
                     /translation="MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNG
                     SVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPK
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            12119..12778
                     /gene="qseB"
                     /locus_tag="RH288_003573"
     CDS             12119..12778
                     /gene="qseB"
                     /locus_tag="RH288_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HDV4032592.1"
                     /translation="MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKP
                     FALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
                     LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGE
                     K"
     gene            12775..14124
                     /gene="qseC"
                     /locus_tag="RH288_003574"
     CDS             12775..14124
                     /gene="qseC"
                     /locus_tag="RH288_003574"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HDV4032593.1"
                     /translation="MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELF
                     DTQLMLFAKRLSTLDLNEINAADRMAQTPNRLKHGHVDDDALTFAIFTHDGRMVLNDG
                     DNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
                     AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRP
                     LVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKAL
                     LQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKID
                     VRLTLNAHSIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGV
                     TPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW"
     gene            complement(14170..>14428)
                     /locus_tag="RH288_003575"
     CDS             complement(14170..>14428)
                     /locus_tag="RH288_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2645 family protein"
                     /protein_id="HDV4032594.1"
                     /translation="FFAFNKYDWMLESGGNICSIPSVSGEDRILQAMIAAFFLLTPLI
                     ILILRKLFMREMFEFWVYVFSLGICLVCGWWLFWGRFIFCY"
BASE COUNT         3536 a         3797 c         3638 g         3457 t
ORIGIN      
        1 ccctcacaga ccgtagaaca aacagtccgg catatttatc agaactataa atcagatgcc
       61 actgcccctt attttggtga aaccggagag cgggcgataa cttctgcgcg tattcaacag
      121 gcgcttaccc tgaacgacaa tcttacgctg ccgggcaata ttggctggct ggattatgat
      181 ccggtttgtg attgtcagga ttttggcgat ctggtgctag aaagcgttgc gataacccaa
      241 actgacgccg atcatgccga tgccgttgtg cgctttcgta tctttaaaga tgataaagaa
      301 aagaccacgc agacactgaa aatggtggcg gaaaatggtc gttgggtcat tgacgatatt
      361 gtcagcaatc atggcagcgt cttacaagca gttaatagcg agaatgaaaa aacgctggcc
      421 gctttagctt cgttgcaaaa agaacagccg gaagcctttg ttgccgaact ctttgaacat
      481 attgctgatt atagctggcc gtggacgtgg gtggtttccg actcttaccg ccaggcggtt
      541 aatgccttct ataaaaccac cttcaagacg gccaataatc ccgatgaaga tatgcaaata
      601 gaacggcaat ttatttacga caatccgatc tgttttggcg aagagtcgct attttcacgc
      661 gttgatgaaa ttcgagtcct ggagaaaacc gccgattccg cccgcattca tgttcgtttt
      721 acgctgacca atggcaacaa cgaagagcaa gaactggttt tacagcggcg cgaaggcaag
      781 tgggaaatcg ctgattttat ccgcccgaac agcggcagcc tacttaagca gattgaggca
      841 aaaactgccg ccagattaaa gcaatgagct gaattaaata acaattagcc ggaacaataa
      901 ataaaaggga acactatatg aaaacgattt tcaccgtggg agctgttgtt ctggcaacct
      961 gcttgctcag tggctgcgtc aatgagcaaa aggtcaatca gctggcgagc aatgtgcaaa
     1021 cattaaatgc caaaatcgcc cggcttgagc aggatatgaa agcactacgc ccacaaatct
     1081 atgctgccaa atccgaagct aacagagcca atacgcgtct tgatgctcag gactattttg
     1141 attgcctgcg ctgcttgcgt atgtacgcag aatgataaaa aaatccccgg tagcgtgtca
     1201 gttgccgggg atatttttta acgtccaacc gccgctttag gccgtttctt cgcaccagca
     1261 ttcaccggac gagattgcgt agacgacgct ttttttgccg tagcaggcgt ctgacgctgg
     1321 gtcgccatcg gcgtatgttt cgtcaacgcc ggacgggtat tgcggttctg gcgacgagct
     1381 tcacgcatct cttcaatggt tggcgcaggc actaagcaat cgcgacggct gccaatcaga
     1441 tgctttttgc ccatcgcttc cagcgcctgg cggattaacg gccagtttgc cggatcgtgg
     1501 taacgcaaca acgctttatg caaacgacgc tgtttgtcgc ccttcggtac gaagacgtct
     1561 tcgctcttat aaccaatctt cgccagcggg tttttcccgg tgtaatacat ggtggttgag
     1621 ttcgccagcg gcgacggata gaagttctgc acctggtcga ggcggaagcg gtgctttttc
     1681 agccacagcg ccagattcac catatcttca tcacgcgtac cggggtgcgc ggagatgaaa
     1741 taggggatca gatactgctc tttacctgcc tgttttgagt aagtatcgaa cagctcttta
     1801 aagcggtcat agctgcccat gcccggcttc atcatcttcg ataacggccc ttcttcggta
     1861 tgttccgggg caatcttcag ataaccgccg acgtgatggg tcgccagttc tttgatatag
     1921 cgcggatctt ctacggctat gtcataacgc acaccagagg caatcaggat ctttttaatg
     1981 cctttcagat cacgcgcacg gcgatagagg ttgatcgttg gttcgtggtt cgtgtccatg
     2041 tgcggacaaa tatccggata aacgcacgac aaacggcgac aagtttgttc agcgcgtggc
     2101 gatttgcagc gcaacatata catgttggca gttggcccac caagatcgga aatcacgccc
     2161 gtaaaacctg gaacggtgtc gcggatcgct tcgatctcat taatgatcga atcttcggaa
     2221 cggctctgaa taatgcgccc ttcgtgctcg gtgatagaac agaaagagca gccgccaaag
     2281 cagccacgca taatgttgac cgaaaaacgg atcatttcgt aagccggaat acgggcattg
     2341 ccataggccg gatgtggcac gcgcttgtat ggcagcgcaa aaacgctgtc catctcttcg
     2401 gtagaaagcg gaatagcagg cgggttgatc cacacatagc ggtcgccgtg tttttgcatc
     2461 aatgcgcggg cacagcctgg gttggtttcg tggtgcagaa tacgcgaagc atgggcgtac
     2521 agcactttat cgcccttcac tttctcgaaa gaaggcagca acacgtaggt tttttcccac
     2581 ggtttcgggc gcggtggctg cacggttacg gctttggctt cctgcttttt cggtgccacc
     2641 ggtttgttat ccgcgcacgg caaatcttca ccatacggat gcgggattgg gtcgattttt
     2701 ccaggggtat caagacgggt ggaatccacg ccgctccagc caggcagcgc ctctttcacg
     2761 ataatcgcgg tattacgcac atcgcggatt tcactaattg gctcgcccat cgccagacga
     2821 tgcgccactt ccaccagcgg acgctcaccg ttaccaaaca tcagcatgtc ggctttcgaa
     2881 tccaccagca cggaacggcg cacggtatcg gaccagtaat cataatgcgc ggtacggcgc
     2941 agactagcct caataccgcc gaggatcacc ggtacatctt tccacgcctc tttacaacgc
     3001 tgggtataaa ccagtgtggc gcgatccggg cgcttacccg cgacgttatc cggcgtgtag
     3061 gcatcgtcat gacgtaaacg gcgatcggcg gtataacggt tgatcatcga atccatgttg
     3121 ccagcagtaa caccgaaaaa cagattcggt ttacccagac gcataaagtc gtctttgctg
     3181 ctccagtccg gctgggcgat gatcccgacg cgaaagccct gcgcttccag catacgaccg
     3241 caaatcgcca tcccgaagct tgggtgatcg acatacgcgt cgccagtaac caaaatgatg
     3301 tcgcagctat cccagccaag ttgatccatc tcttcacgag acatcggcaa aaacggtgcc
     3361 ggtccaaaac aggcggccca gtactgcggc caggagaaca ggtcgcgatc cggttggatc
     3421 agggagatag agctcatttt gcttccagaa atgataaaaa aataatcaaa ggccggggat
     3481 tataagccgg aacgaaagag aaatcgaaag gtattccata ctcgccctcc tcgggcgagt
     3541 atgaagatta cggtaccgga ttgaccaaca gttgcccaat cgagccacgg tccgccattt
     3601 ccagcgtctg actgttgaag tagaacggga agtgcgccca ggaaggctga ccgaaataaa
     3661 caagcagctc cacttgtccg tcaacccaaa cggtatcttt ccagcctctg tcttccggga
     3721 acggcatcgc gccattcacg ttacggatct ggaacattac gccttcaata tggaacgctt
     3781 gcggctcgtc cgcgcgtacc gtccagcgtt cccacgttcc ttgctgcgcg gtgacatcaa
     3841 tacggttgac gtcccacagc tgtccattaa tacccgggtc atcacccaga ctgatatcgc
     3901 gactgcgaat tggcgaacca gccatgattt cagttggcag caagcgcatc ggaagactgt
     3961 ctgtgaccag cggcagaagg ccggttgggc gcagcgttag caccagggta gaaaccagaa
     4021 tactggatgg ctcaaagaag ccacgaatac gatcaacaat gctcgccgct tcgccacagg
     4081 tgatcgacac ttcatcgccg ttgctcatat ccaccagaat ctcgcggcgc tcgcccggtg
     4141 ccagcgaaag ttgcttcacc gatacaggag caggcaggaa tccctgatcg ccagaaatca
     4201 catgtaacgg gcgaccatcg ttcatctgta gttgatagcg acgagagttc gacgcgttca
     4261 gcagtcgcaa gcgcacccag ccacgcgaga cttcaacgta cgggctttgt acaccgttaa
     4321 ccagcagcgt atcaccaaca aagccgccgc ttcccggttc gttgtattct ggcgtaccaa
     4381 agttatccag ccgtttatcc tggataatga ccggaaaatc atccacacca taatggttgg
     4441 ggataggcag cgacttgctg acttcatctt ccaccagcca cattccggca aggccgttat
     4501 agacctgctg agccgtgcgg ttgggagtat tggcgtgata ccacagagta gctgcgttct
     4561 ggcgaatggg cagtacgggt gcccagtcag cgtttggcga catcatccgt gccggaccgc
     4621 ccatcagcgg gcctggtacc tgtagcccgg ccaccgtcat tgagacattt tctgtcaggc
     4681 ggttgctgta aataagctta acatcgtcgc ccttccagac gcggatagtc ggccccaggt
     4741 aacgaccatt gattccccag accgacgcgc gtgtccctgg cgtaaatgac cagtgcgcac
     4801 gttgtacagt cataaacagc ggttgcccac ggcgagattc aagtagcggc ggaacgggta
     4861 gcggttgctg ttgcccggct gcgctggcct tcaggggaac agcgcctgca caaagtgcaa
     4921 tccccgatgc ctgaatgaac tgacgccgac tgagtgacat atttgctcca tgtaaaactg
     4981 gctaaagtaa taccgtgcag gaaagtgttc cccgcaaaaa tacagattgc cgacttaaac
     5041 ttttccggcg gcttcgcgtt ctgcgacttc tttatcgagc tcggcgattt tttgttccat
     5101 tatcgaacga caatgggcag ccagctcacg aacctgatct ttgccatact gactgacgtc
     5161 aattggcggc agcatttcga caatcaccag accgttgtgc agtcgattaa gattaatctt
     5221 attcgaagtt gtagagacgc acacgggaat aatcgggacg cccgccgcaa ttgccgcgtg
     5281 aaatgctcca gtcttgaacg gtagcaggcc gcgaccacgg ctgcgggttc cttccgggaa
     5341 catccagatg gaaatacggc gttttttgaa gtgattcact acttccgcaa tggtgccgtg
     5401 agctttagtg cgattgtttc tgtcgatcaa taagttgccg gttaaccagt acaactgccc
     5461 gaagaagggg atccacagca agctcttttt acctaccgtc accgtcggcg gttgcacgat
     5521 gttcgatgct gtcaccatgt catagttgtt ctggtggtta gcgatataga tagcattgcc
     5581 gtagctttca gcgtctgtag gtttacggca ctcaactttc aggccaaaca gcggcgcaag
     5641 acggccaaac atatgcccaa aggtggccac atgtttcggg ttacgcgggc tgaaaaggca
     5701 gtaaatggag ccgaatacac agactaagat gctgtaaatc acggtaataa taagacgaaa
     5761 gatatatagc ataacaccct ctgaaggtct gagagactgg cattgtacgt cacctgaaat
     5821 caggttaggg cattgttaaa agccgctctc tggaaaagcg tattgttaat cgcaacgcat
     5881 gaataaacaa cggtttcaag ggaattttta tcgtttccgg gggttgaata cgctgccgga
     5941 tgacgactta acgtttcatc cggcgttcct tgcaagcggg aggaaacagc gccctccccg
     6001 gcatattact cttcgctatc accgctgctg gcacggcgag gagagtcgat ctcaacacga
     6061 tcgatacgct gcaaaccgcg catcaacgta ccgcggcgtc cacgttcgcc agtgactttc
     6121 tgtaactctt ccgggcgcag tttaattttg cgtttcccaa catgaatggt cagcgtgctt
     6181 tgcggcggca gaacgtacaa ttgcgccaga ccatcttctc cacgcgcggc ttctgccgat
     6241 ggaatgttga taatcttgtt gcctttgccc ttcgacagct gcggcagatc acttaccggg
     6301 aacatcaaca tacggcctgc ctgagtgatt gccagcagca tatcggaagc atcttcaatc
     6361 accaccggcg gcataacatg ggcattttcc ggtaaggtga tcaaagcctt acctgcacgg
     6421 ttacgcgcca ccagatcgtt aaaggtgcag acgaaaccgt aacccgcatc ggaagccatc
     6481 agcagtttct gatcgtcgct ttccatcagc atatggtcaa cggtcgcccc aggcggcaac
     6541 gttaatttgc cggtgagcgg ctcgccctga ccacgcgccg acggcagcgt aatcgggtca
     6601 atggcatagc tacgaccggt ggaatcaaca aacactaccg gttggttgct cttacctttc
     6661 accgccgctt tgaagctatc acccgcttta taattcaggc ccggcgcgtc gatatcatgg
     6721 cctttagcgc tgcgtaccca gcccatctgc gacagcacaa tggtgacagg ttcagacggc
     6781 agcatgtcgt gctcgctcat cgctttcgct tcttcgcgtt cctgcaacgg cgaacgacga
     6841 tcgtcaccgt aggcttgcgc gtctgcctgc agttctttct tcagcaggtt attcatttta
     6901 cgctcggaag ccaaaatgcc ctgcaactgg tcgcgctctt tttccagttc actctgctca
     6961 ccgcgaatct tcatctcttc cagtttggca agatgacgca gtttcagttc gaggatcgct
     7021 tccgcctggg tttccgtaag gccaaaccgc gacatcagcg ccggtttcgg ttcatcttca
     7081 ttacgaatga tctcaatcac ttcgtcgata ttgagaaacg ccaccagcaa accttcgagg
     7141 atatgcaggc gcttgaggac tttctccaga cgatagttca gtcggcggcg cacggtatcg
     7201 cggcggaaca ccagccattc ggagaggatt tccagcaggt ttttcaccgc cggacgacca
     7261 tccagaccga tcatattaag gttaatacga tagctctttt ccagatcggt ggtagcgaag
     7321 aggtggttca tcacctgatc catatccacg cggttggaac gcggcacaat caccaggcgg
     7381 gtcgggttct cgtggtcaga ttcatcgcgc agatcgtcaa ccatcggcag ctttttgttg
     7441 cgcatttgcg cagcaatttg ctccagtacg cgcgcacctg aaacctgatg cggcaatgcg
     7501 ctgataacca ccgcgccatc ttctttcttc cacaccgcgc gcatacgcac tgaaccacgt
     7561 ccgttctcgt agattttacg gatctcggcg cgcgaagtga taatttccgc ttcagtcgga
     7621 taatccggcc cctgcacgat atccagcagc tgatcgagcg tggttttcgg ctggtcgatt
     7681 aatgcgattg ccgcctgagc cacttcacgc aggttatgcg gtggaatatc ggtcgccatg
     7741 ccgacggcaa taccggtggt gccgttaagc aaaatgtttg gcagacgggc aggtagcatt
     7801 ttcggctcct gcaaagtgcc gtcgaagttt ggcacccagt cagccgtccc ctgccccagc
     7861 tcgctcaata gcagctcgga atatttcgac aaccgggatt cggtgtaacg cattgccgcg
     7921 aacgatttcg gatcgtccgg cgcgccccag ttcccctgac catcaaccag cggataacgg
     7981 taagagaacg gttgcgccat caggaccatc gcttcataac aggcgctatc gccgtgcgga
     8041 tggtatttac ccagtacgtc accgacggta cgggccgatt ttttaaattt ggcgctggca
     8101 ttcaggccca gttcagacat cgcatacaca atgcggcgct gaacaggttt cagaccatca
     8161 ccaataaacg gcaacgcacg gtccatgatc acgtacatgg agtagtttaa gtaggcgttt
     8221 tccgtaaatt catgtagcgc aaggcgctct gccatatcgc tcattaattc tgattcctca
     8281 acttattcgc cagccttcaa aggggcaata ttgccggaga tactacatta tctgccgcgt
     8341 cgagtcacag gagatcagcg tgaatagcgc cgccggacgt gctccgacgg cgataaaggc
     8401 atcaatgtgc cttgatatac aactctttgc tgtagacata atcctgggga ttatgcagcg
     8461 gaaaaccgcc aacgtagggt ttaagcagtt tgattaacgg ctgatagtag ataggaatca
     8521 gcggtgcctg ttggttgatg atcacttctg cctgctgata caacgcatta cgctttgtcg
     8581 catcagtgat ctgcgtggcc tggtttagta aggcgtcata ctgcgcattt ttccagtgac
     8641 cgacgttttc ttcactatcg cttttgagcg tgttcaggaa gctggaagca tcattgtacg
     8701 tcgcatccca cgactgccga gacagcatga aatcaccggc tcgtcgggca tcaagatagg
     8761 ttttccactc cattgtgcgc agcgtcacct gtgcacccag ccattttttc cattcggaag
     8821 acaacgctat cgcggtcttt tcatgcagat cgtacttgtt gtagaacagc tcaaagcgta
     8881 gcggatgaga ggcgtcgtat cccgcctgtt tcagcaaggc ttttgccatc gcgacgcgct
     8941 cactcattgg cttttgcagt tcatcgaacg tcgtcgcgct aaagcctttt acctctggcg
     9001 gcgtcagcgt ggttgcgggc gttctcaacc ccagtacctt ttgcgcaata agctgtcgat
     9061 caaccgtaag atatagcgcc cgacgcactc gcacatcgtt aaatggcggt ttctcaaggt
     9121 tgaagttgta atattcgctg ttcagacgcg gaataattcg tagctcgcca ggcagtgatt
     9181 tttcaatggc gggaatttgc tgcgccggaa cccaggtgag atcgacctct cccgcgcgat
     9241 agcggttata gccggtgacc gaattatcta gcgccagata ctcaacctgt tgcaatactg
     9301 tatgttgcgc atcgcggtac tttggatttt tgcgtgcagt aatcttttcg ttaactaccc
     9361 actgatcaag cacaaaggca ccgttgtaaa ccatgttctc tggcttactc cagctatcgc
     9421 catgtttagc gatgacatga tgaggaaccg ggaacagcgt cggccaggcg agcatcgtcg
     9481 tgaaccaagg aaccggctgc tcaagcgtaa cttcaagagt acgatcatcc gtcgctttga
     9541 cacccagcga tgtaacatct gctttacccg caacaatagc tgcggcattg ttaatgtgcg
     9601 cctgtgccag atagccagca aaagggcttg ccgttttcgg gtcaaccgcg cgctgccagc
     9661 cgaggacaaa atcctctgcc gtcagaggct gaccgtcgga ccactgcaaa ccgctacgca
     9721 gatggaaaat atagcgcttg ccgccgtcca gtatctccca gcgttcagcc tgagcgggct
     9781 gcacctggcc ttcaccgtcc atccatacca gaccttcaaa cagatccagc acaatctgcg
     9841 cggcagtatt ctcctccacc ttttgcgggt cgagcgtacc tgggtcgcta tgattgttgt
     9901 aacgaaagac ttgttgcggg gcgagcggtg tgttggcggg aacgtcagca gcgtagagag
     9961 gagccgcact taccaggctg accagccata ataaatttcg cgtatacatg gtattcctta
    10021 ccggagaaat tataagccca acaacaatac gcctgtggca ttgttcgctc aaacttatcg
    10081 cgagtgattt ggctcacact ccggtaaaga aaaaagcgag ttgcccccgc ttttccatta
    10141 attaacggat ttcattcaat agttctggat gcttatccag aacacgtaaa agtttgattg
    10201 tggaaggatg aggttgggca ttgccttttt cgtaacgcga aaacgcattt acacctcccc
    10261 caaaaatttc gcttgcctct ttttgggtaa gagagagctt ttttcgaacc ttcactataa
    10321 attcaggtgc cactgtttcg gcattcaccg aagcccgaaa tgcctttact tgcgccatga
    10381 aagcatctga ctcttcttta ttcatgatgc tctcttcgca atggacacaa tataaaccgt
    10441 ggataccttt caatactgtt tttcgtccac ggaaggtgta tggaatatct ttaatgccag
    10501 aaaccatttc tccctggtgg caaaccggac atttcatatt acttctcctt aaacgagacg
    10561 atcagtacgt catgaattac cgtaatttta agataaacct ggcctgtaac aagcctgggt
    10621 ctgtaaacat cctgccagat agtatgatca gagtaggtgg tcatgctttt ataaaagtcg
    10681 ctctctgata atccaatgat aacattacac ataccatcaa aatccaaacc taactcatct
    10741 gcatttaaca gggcactacg tgttgtacga acttgcccgg cattgacaag ttttttaacc
    10801 tgactcaaac gtgtatgtgg tgtgcgtttt tccataaccc ccgcctccct gttactttag
    10861 ttataaccta aaaggttaat tacagcaatg aaaaagcacc taaaaggtta gttagatgta
    10921 cggagatagt gaccacacaa aacgtattct ttaaggaaag tgattgacca tataagaaag
    10981 tggcgcatta gtagcgccag tttgaagcag gaatttataa gggaagctgg agtcaggcat
    11041 cacgccaacg gcacataaac atccgtttcc agtcgctgct ctgtcacccc ttcggcaaga
    11101 ttggtgtagt gaaacagaat cggtgcttta cgcattttct cgccgcttgc aggcagccag
    11161 tggcgaatga tgccccatac cgtgtgtgaa atatcgtcca gctcgccaac gtggcgggcc
    11221 acggcataac gtccaccggt aagttcacca ttgctcacac cataacgatt atcgggaatc
    11281 ggttcgctaa cgctgccgca gatatcaaag cgaaacgctt ccggtgcggt ggtggcaggg
    11341 tcgtcccagg cgacgccaaa agtctggctt tggttaacag gagaaagccc cgtctcttta
    11401 cgccacatga taaatttcgc cacgctgtag ttgagcaatt cagggctaca gcggtgcggc
    11461 aacatcgcca caggtattga tgggaaatcg ataatgttta catccagtgt caggtttgtc
    11521 attttgcctc cctgcgaaat tattcccggg aacgcgtccc gggagcggta acaattacgg
    11581 atttactttg cggatctgtt tgacgtcaat ttcaacagaa ttccagtctt tatcgacttc
    11641 accctgaatc tcaaccgtat ctttcggcgt caccgtcacg ccgttccagc gtttgtggtc
    11701 gatatcaaca ttgatagtac cgctggcatc tttgaacacg tagagatcgt cagagatgcg
    11761 ttcaacgata ttgccgcgca gggttaccca ggtgtcgtca cgcagggatt ttgcgctttc
    11821 tacagtcgtt acgctgccgt tcggcccctg gaatcctccg gcctgacttt gcgttgccga
    11881 tgggccagaa aaaccgccct gctctgctgc catcaccggt gcgctgcaca gggccattac
    11941 tgcgattact gctgcgaatt ttttcatgtt tattactccc tttaatgtct gtttccgagc
    12001 atttaacaag atagtcctta acaacttctt aagggaaaaa aataaaattt agtgctgtac
    12061 agagcgcgtt acaacacggt ttactggcag caaatacggt tatcgcaggg atgaaaaaat
    12121 gcgaatttta ctgatagaag atgacatgct gattggcgac ggcatcaaaa cgggccttag
    12181 taaaatgggt tttagcgtcg actggtttac acaaggtcgt cagggaaaag aggcgcttta
    12241 tagcgcacct tatgatgcgg tgatcctgga tttaacctta ccaggcatgg atggtcgcga
    12301 tattttgcgc gaatggcgag aaaaaggtca gcgtgagccg gtactgatcc tgaccgcgcg
    12361 cgatgcgctg gcggaacgtg tagaagggct gcgtctggga gctgacgatt atctgtgtaa
    12421 accttttgcg ttgatagaag tcgccgccag gctggaagct ctgatgcgcc gaaccaacgg
    12481 ccaggccagc aacgagctgc gccacggtaa cgtcatgctc gaccccggca aacgtatcgc
    12541 cacgctggct ggcgaaccct taacactgaa accaaaagaa tttgccctgc tggaattact
    12601 gatgcgtaac gctggtcggg tactgccgcg caaactgatt gaagagaaac tgtatacctg
    12661 ggacgaagag gtcaccagta atgccgttga agtgcatgtg catcatctgc gacgcaaact
    12721 cggtagtgat tttattcgta ccgtgcatgg tattggttac acattaggtg agaaatgaaa
    12781 tttacccaac gtcttagtct gcgcgtcagg ctgacgctaa tctttttaat tctggcctcg
    12841 gtgacctggc tgctttccag ctttgtcgcc tggaaacaaa caacggataa cgtcgatgaa
    12901 ttgttcgaca cccaactgat gctgtttgcc aagcggttaa gtacgctcga tctcaacgaa
    12961 atcaacgcgg cggatcgcat ggcacagacg ccaaatagat taaaacacgg tcatgttgat
    13021 gacgatgcgc tgacctttgc catctttacc cacgacggca gaatggtcct taatgatggc
    13081 gataacggag aagatattcc ctatagctat caacgggaag gttttgctga cgggcaactg
    13141 gtcggtgaag acgatccttg gcgttttgtc tggatgacct cacctgatgg caaatatcgc
    13201 atcgttgttg gccaggaatg ggaataccgt gaagacatgg cgctggcgat tgttgccggg
    13261 caattgatcc cgtggctggt cgcactgccg attatgttaa tcatcatgat ggtactactg
    13321 ggtcgtgaac tcgcgccgct gaacaaactg gcgctggcac tacgtatgcg tgaccctgac
    13381 tcggaaaaac cactaaacgc gactggcgta cccagcgaag tgcggccact ggttgagtcg
    13441 ctaaatcaac tgttcgcccg cacacatgcg atgatggttc gtgaacgacg ctttacctcc
    13501 gacgcagctc acgaacttcg tagcccgtta acggcgctga aagtgcaaac cgaagttgcg
    13561 cagctctctg acgatgatcc gcaggcgcgg aaaaaagcac tgctccaatt acattccggg
    13621 atcgatcgcg ctactcgtct ggttgatcaa ctgctcacgc tatcgcggct ggactcactg
    13681 gataaccttc aggacgtcgc ggagatcccg cttgaagatc tcctgcaatc gtcggtgatg
    13741 gatatttacc acacggcgca gcaggcgaaa attgacgtgc gactgacact caatgcccac
    13801 agcatcaaac gcaccgggca accgctattg ctaagtttgt tggtgcgaaa tttgctggat
    13861 aacgccgtgc gctacagtcc acagggcagc gtggtagacg tcacgctgaa tgctgataat
    13921 ttcatcgtga gggataacgg ccccggtgtg acaccagagg cactggcgcg aattggcgaa
    13981 cgcttctatc gcccacccgg acaaaccgct accggcagcg ggcttgggct atcgattgtc
    14041 cagcgaatcg ccaaattgca tggcatgaat gttgaatttg ggaatgcgga acaaggtgga
    14101 tttgaggcga aggtaagctg gtaacttctc tgtctatgag agccgttaaa acgactctca
    14161 tagattttac taatagcaaa atataaaccg tccccaaaaa agccaccaac cacaaaccag
    14221 acaaataccg agcgagaata catataccca aaactcgaac atttcccgca taaagagttt
    14281 tcttaagata agaataataa gtggcgtaag aagaaaaaat gctgcaatca ttgcttgcaa
    14341 tatacgatct tcgcctgaaa cggaaggtat actgcaaata ttccctcccg actcaagcat
    14401 ccagtcatac ttattgaaag caaaaaaa
//
LOCUS       DAPHKZ010000114        14412 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.114, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000114 DAPHKZ010000000
VERSION     DAPHKZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14412
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.114"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..209
                     /locus_tag="RH288_003576"
     CDS             <1..209
                     /locus_tag="RH288_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV4032595.1"
                     /translation="SERQLLLNQANEYMNSKQWPGKAAIGRLKGDELAQYNLWLDYLD
                     ALELIDTSGAPDIEWPTPPAVQAR"
     gene            complement(181..783)
                     /locus_tag="RH288_003577"
     CDS             complement(181..783)
                     /locus_tag="RH288_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV4032596.1"
                     /translation="MDNAVLNSELIATKAGNITVYNYDGKTREYISTSNEYLAIGVGI
                     PAYSCLDELGIHKAGYAICRSMDLNSWEYVPDHRGEIVYNTETGDAKEITAPGDYPEN
                     TTTIAPLTPFDKWDGKKWVTDTEAQHSAAVDAAEVQRQSLINTAMASISLIQLKLQAG
                     RKLTQAETTRLNAVLDYIDAVTATDTSTAPDVIWPELPEA"
     gene            complement(783..2312)
                     /locus_tag="RH288_003578"
     CDS             complement(783..2312)
                     /locus_tag="RH288_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4032597.1"
                     /translation="MSTKFYTLLTDIGAAKLASAAALGVPLKITHMAVGDGGGALPTP
                     DAKQTALVNEKRRAALNMLYIDPQNSSQIIAEQVIPENEGGWWIREVGLFDESGALIA
                     VGNCPESYKPQLAEGSGRTQTVRMVLITSSTDNITLKIDPAVVLATRKYVDDKVLELK
                     VFVDDKMAKHLAAPDPHSQYAPKESPTLTGTPKAPTPAEGNNTTQIATTAFVQAALTA
                     LINGAPATLDTLKEIAVAINNDPKFSTTINNALALKAPLSSPALTGTPTAPTAAQSVN
                     NTQIATTAFVKSAIAAMVGSAPAALDTLNELAAALGNDPNFATTMLNALAGKQPLDNT
                     LTNLSGKDVAGLLAYLGLGEGSALPVGVPVPWPSATPPTGWLKCNGAAFSAEEYPELA
                     KAYPTNKLPDLRGEFIRGWDDGRGIDAGRVLLSIQTGMLEKHRHIVVANDGYDTKDEW
                     ELATIFKKTYTQGRGLDATNTGGSLIPSPTLHSRGSIGNTGGSETRPRNIAFNYIVRA
                     A"
     gene            complement(2309..2914)
                     /locus_tag="RH288_003579"
     CDS             complement(2309..2914)
                     /locus_tag="RH288_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HDV4032598.1"
                     /translation="MNSLLPPGSTSLERRLAQTCSGISDLQVPLRDLWNPATCPVSFL
                     PYLAWAFSVDRWDEGWTESVKRQVVKDAFYIHQHKGTTSAVRRVVEPFGFLIRIIEWW
                     QTGETPGTFRLDIGVQDQGITEDTYLELERLISDAKPCSRHMIGMSINLQTSGPHWVG
                     AASYLGEEITIYPYINETIISGGTAHEGGAVHVIDTMRVNP"
     gene            complement(2907..3815)
                     /locus_tag="RH288_003580"
     CDS             complement(2907..3815)
                     /locus_tag="RH288_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate assembly protein"
                     /protein_id="HDV4032599.1"
                     /translation="MAVIDLSQLPAPQIVDVPDFETLLAERKAEFVALHPKDEQEAVI
                     RTLELESEPVTKLLQENAYRELLLRQRINEAAQAVMVAYAMGGDLDQLAANYNVKRLT
                     VTPADNDAVPPVAAVMESDEALRLRVPAAFEGLSVAGPTAAYEFHARSADGRVADASA
                     TSPAPAEVVLTVLSREGDGTAEKDLLDVVEKALNSENVRPVADRLTVRSAEIIPYRVE
                     ATIFLYPGPEAEPVMAAAKVSLQRYIASQTRLGRDIRRSAIFAALHVEGVQRVELASP
                     LADVVLNKTQAASCTQWSVTNGGTDE"
     gene            complement(3802..4161)
                     /locus_tag="RH288_003581"
     CDS             complement(3802..4161)
                     /locus_tag="RH288_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013098787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HDV4032600.1"
                     /translation="MTLYIGMSQSNGKAITDTDHLRQSVRDILLTPQGSRIARREYGS
                     LLSALIDQPQNPALRLQVMSAVYVALSRWEPRLTLDSITINSNFDGSMVVELTGRRNN
                     GVPVSLSVSTGAENGSD"
     gene            complement(4158..4736)
                     /locus_tag="RH288_003582"
     CDS             complement(4158..4736)
                     /locus_tag="RH288_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001552634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HDV4032601.1"
                     /translation="MNAQLTEIMRLITNLIRTGVVTEVDRENWLCRVKTGELETNWIS
                     WLTMRAGNARTWWRPSEGEQVVLLSLGGNLETAFALPAIYSNQFAPPSTSADACVTEH
                     PDGGWFEYEPATGRWYVRGIKSMVIEAADNITMKTSEFVLEADRTRINSEVVINGGVT
                     QGGGAMSSNGIVVDAHQHTGVLKGGDTTGGPV"
     gene            complement(4805..5251)
                     /locus_tag="RH288_003583"
     CDS             complement(4805..5251)
                     /locus_tag="RH288_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HDV4032602.1"
                     /translation="MAELQKVDDWLSALLANLEPAARSRMMRQLAQELRRTQQQNIRM
                     QRNPDGSSYEPRRVTARSKKGRIKRQMFAKLRTTKYLKTAASADSASVQFEGKVQRIA
                     RVHHYGLRDRVSRKGPEVRYAERRLLGVNDDVEAMTRDMILQWLAG"
     gene            complement(5244..5675)
                     /locus_tag="RH288_003584"
     CDS             complement(5244..5675)
                     /locus_tag="RH288_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4032603.1"
                     /translation="MNKPQSLRHALNKAVPYVRNNPDKLHLFVDNGSLVATGASSMSW
                     EYRYTLNAVIEDFSGDQNLLMAPVLLWLRDNQPDAINNPALREKLFTFEVDILRNDVC
                     DISLNLQLTERVLVSTDGSVSSVEAVAEPDEPEEKWTVKRG"
     gene            complement(5771..6199)
                     /locus_tag="RH288_003585"
     CDS             complement(5771..6199)
                     /locus_tag="RH288_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HDV4032604.1"
                     /translation="MNRLLLVVLALLLAALGWQTWRLADASQTISTQSDELQSKSQAL
                     AKSNSQLISLSILTETNNREQARLYAEAEQTSALLRQRQHRIEELKRENEDLRRWADT
                     PLPADIIRLRERPTLTGGAAYRQWLSASDAVSAGAGNAAH"
     gene            complement(6196..6573)
                     /locus_tag="RH288_003586"
     CDS             complement(6196..6573)
                     /locus_tag="RH288_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032605.1"
                     /translation="MKKKLISGLFLMLWMALLIAAMVYPQGIFPVLAASGVWVACLLT
                     WAVIPVALAALIKNSPLWQELRASLLKTITRKENVFISWVMRLLIVVSLAWTGWAITL
                     VFYLLTVIAFWITRNQMAQQVAA"
     gene            complement(6575..7087)
                     /locus_tag="RH288_003587"
     CDS             complement(6575..7087)
                     /locus_tag="RH288_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HDV4032606.1"
                     /translation="MNPSIVKRCLVGTVLAIAATLPGFQQLHTSVEGLKLIADYEGCR
                     LQPYQCSAGVWTDGIGNTSGVIPGKTITERQAAEGLISNVLRVERALERCVKQQPPQK
                     VYDSVVSFAFNVGTGNACSSTLVKLLNQRRWADACRQLPRWVYVKGVFNQGLDNRRAR
                     EMAWCLQGAN"
     gene            complement(7068..7283)
                     /locus_tag="RH288_003588"
     CDS             complement(7068..7283)
                     /locus_tag="RH288_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032607.1"
                     /translation="MTLERISAFITYCIAVVLAWLGDLSIKDISTLGGLMIGVLMLAI
                     NWYYKHKAYQLLRDGQITREDYESINR"
     gene            complement(7287..7490)
                     /locus_tag="RH288_003589"
     CDS             complement(7287..7490)
                     /locus_tag="RH288_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HDV4032608.1"
                     /translation="MKVRAHQYDTVDALCWRHYGRTQGVTEQVLKANPGLAEYGPFLP
                     HGLQVELPDIPATTTVQTVQLWD"
     gene            complement(7490..7954)
                     /locus_tag="RH288_003590"
     CDS             complement(7490..7954)
                     /locus_tag="RH288_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HDV4032609.1"
                     /translation="MKFVAPEQAPEQAEIIRNTPFWPDVDLSEFRSVMRTDGTVTQPR
                     LKQVALSAISEVNAELYEFRRRQQMLGYASLAEVPAEQLDGKSERIQHYFNAVYCWAR
                     AMLNERYQDYDTTASGVKRGEELAEASGDLWRDARWAISRVQDAPHCTVELI"
     gene            complement(8050..8700)
                     /locus_tag="RH288_003591"
     CDS             complement(8050..8700)
                     /locus_tag="RH288_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HDV4032610.1"
                     /translation="MSLSPARQHRLRVQAEQAAREGGSVRHASGYDLMLLQLAEDRRR
                     LKGVQSTVKKAEIKVELLPKYADWAEGVLAAGGAQQDDVLMYVMLWRIDAGDYAGALE
                     IGRHALRHGWVMPLGNRNVQTVLAEEMADAAQSAMLAATGFDADLLLQTLELTDGMDM
                     PDQSRARLHKAIGAVLSENNPASALNHLNHALQLDPRCGVKKDKQQLERRLRNDSR"
     gene            complement(8704..9762)
                     /locus_tag="RH288_003592"
     CDS             complement(8704..9762)
                     /locus_tag="RH288_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HDV4032611.1"
                     /translation="MKKNTRFAFNAYLQQLARLNGVAVEELSSKFTVEPSVQQTLEDQ
                     IQQSAAFLTLINVTPVTEQSGQLLGLGVGSTIAGTTDTSAKEREPVDPTLMVDVEYKC
                     EQTNFDTVLTYAKLDLWAKFQDFQVRIRDAIVKRQALDRIMIGFNGVKRAKTSNRSEN
                     PLLQDVNKGWLQKIREDASDHVMGSTTTGGETTPGAVKVGKGGEYANLDAVVMDAVNE
                     LIDVVYQDDDDLVVICGRELLSDKYFPLVNKEQENSEKLAADMIISQKRMGGLQAVRA
                     PFFPPNALLITRLDNLSIYWQEDTRRRSVIDNPKRDRIENFESVNEAYVVEDYRCAAL
                     VENIQIGDFSAAAAETGA"
     gene            complement(9779..10612)
                     /locus_tag="RH288_003593"
     CDS             complement(9779..10612)
                     /locus_tag="RH288_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HDV4032612.1"
                     /translation="MTVKAKRFRIGVEGATTDGREIQREWLEQMAASYNPAVYTALIN
                     LEHIKSYLPDSTFNRYGKVTALFAEEITEGPLAGKMALYADVEPTESLVELVKKGQKL
                     FTSMEVSPKFADTGKAYLVGLAATDDPASLGTEMLTFSASAAHNPLANRKQNPANLFT
                     AAEETVIELEEIQDDKPSLFARVTALFTKKEQSDDARFADVHKAVELVATEQQNLSAR
                     TEKSLSEQEERLSELETALQAQLTAFNELVDKLSHEDSRQDYRQRATGGNAPADTLTN
                     C"
     gene            10755..12521
                     /locus_tag="RH288_003594"
     CDS             10755..12521
                     /locus_tag="RH288_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HDV4032613.1"
                     /translation="MNTTLTPADLDPRRQAMLLYFQGYRVARIAEMLGEKVATVHSWK
                     KRDKWGDYGPLDQMQLTTAARYCQLIMKEHKEGKDFKEIDLLARQSERHARIGKFNNG
                     GNEADLNPNVANRNKGPRRQPEKNVFTDEQIEKLEEIFHSSMFNYQRHWWEAGKTNRI
                     RNLLKSRQIGATFYFAREALIDALLTGRNQIFLSASKAQAHVFKQYIIDFAKEVEVEL
                     KGDPMVLPNGATLYFLGTNARTAQSYHGNLYLDEYFWIPKFQELRKVASGMAIHKKWR
                     QTYFSTPSSLTHSAYPFWSGALFNRGRNKADKVDIDLSHSNLAPGLLCADGQYRQIVT
                     VEDAVRGGCNLFDLGQLRMEYSPDEYQNLLMCEFVDDLASVFPLSELQACMVDSWEVW
                     TDFHALALRPFGWREVWIGYDPAKGTQNGDSAGCVVVAPPAVPGGKFRILERHQWRGM
                     DFRAQADAIKKLTEQYNVTYIGIDSTGVGHGVYENVKAFFPAVREFVYNPNVKNALVL
                     KAYDIISHRRLEFDAGHTDIAQSFMAIRRATTASGNRPTYEASRSEEASHADLAWATM
                     HALFNEPLQGESANTSNIVEIF"
     gene            12521..13567
                     /locus_tag="RH288_003595"
     CDS             12521..13567
                     /locus_tag="RH288_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001580537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV4032614.1"
                     /translation="MGKSKKNRAASTNQIQHKSQTSAEAFSFGDPVPVLDRRELLDYV
                     ECVQMDRWYEPPVSFDGLARTFRAAVHHSSPIAVKCNILTSTYIPHPLLSQQAFSRFV
                     QDYLVFGNAYLEKRTNRFGEVIALEPALAKYTRRGLDLDTYWFVQYSLTTQPYQFTKG
                     NVFHLMEPDINQEIYGLPGYLSAIPSALLNESATLFRRKYYINGSHAGFIMYMTDAAQ
                     NQEDVNNLRNAMKSAKGPGNFRNLFMYSPNGKKDGLQIIPLSEVAAKDEFLNIKNVSR
                     DDMMAAHRVPPQMMGIIPNNTGGFGDVEKASRVFVRNELMPLQKRLLELNNWLGEKVI
                     RFETYDLGLKSKRG"
     gene            complement(13918..>14412)
                     /locus_tag="RH288_003596"
     CDS             complement(13918..>14412)
                     /locus_tag="RH288_003596"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032615.1"
                     /translation="LRLELFNVLRIPDKDAHIEDILRFKDDCQDDLNALHEYLEKLYT
                     EVLYSRDPNLTRAKNFSLLQEAVVNLDKAIEGKWRNPIRMGVKANPEVDGGQVMEFLK
                     PLYHAAIAGYSGGIIPGMVTALATAIPSFIKFQPEWVGFRDKGPKELAYLTKATHKGL
                     IKRA"
BASE COUNT         3130 a         4206 c         3696 g         3380 t
ORIGIN      
        1 aatcagaaag gcaattattg cttaatcagg ccaacgaata catgaacagt aagcaatggc
       61 ccggtaaagc cgctattggt cgtctgaaag gtgatgaact ggcgcaatat aatttgtggc
      121 tggattatct ggacgcactg gagctgatcg atacttccgg tgcgccagat attgaatggc
      181 ctacgcctcc ggcagttcag gccagatgac atccggcgct gtgctggtat ctgttgccgt
      241 caccgcgtca atgtaatcca gcacagcgtt aaggcgggtt gtttctgcct gcgtcagctt
      301 ccgtccggcc tgcaatttaa gttgaatcag actaatggaa gccattgcag tattaatcag
      361 tgactgacgc tgtacttctg ccgcgtctac tgcggcgcta tgctgtgcct cagtatcggt
      421 cacccatttc ttaccatccc atttatcgaa tggcgttaac ggggcgatag tggttgtatt
      481 ttcaggataa tcacccggag ctgtgatttc tttggcgtct cccgtttcgg tgttatagac
      541 gatttcaccg cgatggtctg gcacatattc ccatgagttt aaatccatcg aacggcagat
      601 agcataaccc gccttatgta taccaagttc atccagacag gaatatgcag ggataccgac
      661 accaatggca agatattcat ttgaagtaga aatatattcc cgagttttac catcatagtt
      721 atagacggta atattccccg ccttcgtggc aataagctcg ctatttaata cggcgttatc
      781 cattatgcag ccctcacgat atagttaaat gcaatatttc gtggacgggt ttcactcccg
      841 ccagtattac cgatactccc tcgtgaatga agtgtcggtg atgggatcag actccctcct
      901 gtatttgtgg catcaagtcc ccgtccttgt gtgtatgtct ttttgaaaat cgtagccagt
      961 tcccattcat cttttgtgtc gtaaccatca ttggcaacaa caatatggcg gtgtttttcc
     1021 agcatccctg tctgaatgct caataaaaca cgtcctgcat caataccgcg cccgtcatcc
     1081 cagccacgaa taaactcacc acgtaaatca ggcaatttat ttgtcggata agcctttgcc
     1141 agttccgggt attcttcagc agaaaaagcc gcaccgttgc atttcagcca gcctgttggc
     1201 ggtgtggctg aaggccatgg aacaggcaca ccaacaggta atgcagagcc ttctcccaaa
     1261 ccaaggtatg cgagaagacc agctacatcc tttccactca aattggtaag cgtattgtcc
     1321 agcggttgtt tacctgccag cgcattaagc attgtcgtgg caaagttcgg atcattcccc
     1381 agtgccgccg ccagttcgtt cagtgtatcc agtgccgcag gtgcagaacc caccattgct
     1441 gcaatcgctg atttcacaaa agctgtagtg gcaatctgtg tattgttgac cgactgtgcc
     1501 gcagtaggtg ctgttggcgt tccggtgagt gccggactcg acagtggcgc tttcagtgcc
     1561 agcgcattgt taatggtggt actgaatttc ggatcattgt taatggctac ggctatttct
     1621 ttcagcgtgt ccagcgtggc tggcgcacca ttaataagag ccgtcagtgc cgcctgaaca
     1681 aacgcggtgg tcgcaatctg cgtggtgtta ttcccctccg ctggcgttgg cgctttgggt
     1741 gttccggtca atgtcgggct ttctttgggt gcatactgtg aatgcgggtc cggtgcggca
     1801 agatgttttg ccatcttatc atccacgaac accttcagct ccagtacctt gtcatccaca
     1861 tacttgcggg ttgccagcac gacggcaggg tcgattttca gggtgatatt gtccgtgctg
     1921 ctggtaatca gcaccatgcg cacggtctgg gtgcgcccgc tgccttcagc cagttgcggc
     1981 ttatagcttt ccgggcagtt gcccacggca attaatgccc ctgactcatc aaacaggccc
     2041 acttcacgga tccaccaacc accctcattt tcagggatca cctgttcagc aataatctgg
     2101 ctgctgttct gcgggtcgat atagagcata ttcagcgcag cccggcgttt ctcatttacc
     2161 agtgccgtct gctttgcgtc cggcgtcggc aatgctccgc cgccatcgcc caccgccata
     2221 tgggtaattt ttagcggcac gccgagcgcg gcggcgctgg caagtttcgc cgcgccaata
     2281 tccgtcagca gggtataaaa ttttgtgctc atggattcac tctcattgtg tcaataacat
     2341 ggaccgcccc gccttcatgc gcggtgccgc cggaaataat tgtttcgttg atatacggat
     2401 agatcgtgat ttcttcgcca agataactgg cggctcccac ccaatgcggg ccgctggtct
     2461 gcagattgat ggacatgccg atcatgtgac ggctacatgg tttggcatcg cttatcagtc
     2521 gctcaagttc cagataggta tcttcagtga tgccctggtc ctgcacacca atgtccagac
     2581 gaaacgtgcc cggtgtttct ccggtctgcc accactcaat aatgcggatc aggaagccga
     2641 acggctccac cacccgccgt acggcactgg tggttccttt gtgctgatga atataaaaag
     2701 catccttcac tacctggcgt ttgacgcttt ctgtccagcc ctcgtcccag cgatccacag
     2761 agaacgccca ggcgagataa ggcaggaaac tgaccggaca ggttgctgga ttccacaagt
     2821 cacgcagcgg cacctgcaga tcagaaatcc cgctacaggt ctgcgccagt cggcgctcca
     2881 gtgaagttga acccggtggc agcagactat tcatccgttc ctccgttggt cacgctccac
     2941 tgcgtacatg atgccgcctg cgttttgttc agaaccacat ccgccagcgg agaagccagt
     3001 tccacacgtt gaacaccctc aacatgcagc gcggcaaaaa tagcactacg gcgaatatcc
     3061 cgaccgagcc gcgtctgact ggcgatgtac ctctgcaggc tgacttttgc cgctgccatt
     3121 accggctctg cttccggtcc cggataaaga aaaatggtgg cttccacacg gtacgggatg
     3181 atttctgcgc tgcgaaccgt cagacggtca gccaccgggc ggacattctc actgttcagg
     3241 gctttctcca ccacatccag caaatctttt tctgctgttc cgtcgccttc acggctcagg
     3301 acagtcagca ccacctctgc aggtgccgga ctggttgcac tggcatccgc cacccgaccg
     3361 tcggcgcttc gggcatgaaa ttcataagcg gcagttggcc ccgcaacaga aagcccttca
     3421 aaggctgcgg gcacacgcag gcgtaacgct tcatcgcttt ccatcacagc cgcaacgggt
     3481 ggcacagcgt cattatcagc aggcgtcacc gtcaggcgtt tcacgttgta gttggcagcg
     3541 agctggtcaa gatcgccgcc catcgcgtaa gccaccatca ccgcctgcgc ggcttcgtta
     3601 atgcgctggc gcagaagcaa ctcacggtaa gcgttctcct gcagcaattt ggtgacgggt
     3661 tcagattcca gttccagcgt gcggatcact gcttcctgct catctttcgg atgaagcgcc
     3721 acaaattctg ccttgcgttc ggcaagcagc gtctcaaagt ccggcacatc cacaatctgc
     3781 ggcgcaggca actgcgaaag gtcaatcact gccattctct gctcctgttg atacggaaag
     3841 ggacacaggc acaccgttat tccgccgccc ggtcagctcc accaccatag aaccgtcaaa
     3901 gttgctgttg atggtgatgg aatccagcgt cagccgtggc tcccagcgac tcagcgccac
     3961 atacactgcc gacatgacct gcaggcgcaa tgccggattt tgtggctggt ctatcagcgc
     4021 cgacagcagg gaaccatatt cccgacgggc aatgcggcta ccctgtggcg tcagcaaaat
     4081 gtcccgcacc gactggcgca gatggtccgt gtctgtaata gcttttccgt tgctctgact
     4141 catgccgata tacagcgtca taccgggcct ccggttgtat cgccgccttt caggacgcca
     4201 gtatgctgat gcgcatcaac cacgatcccg ttagaactca tcgctccgcc gccctgggta
     4261 acgccaccat tgatcaccac ttcgctgtta atgcgcgtgc ggtcagcctc cagtacaaac
     4321 tcactggttt tcatggtgat gttgtcagcg gcctcaatga ccattgattt gatgcccctg
     4381 acataccagc gcccggtggc gggttcgtat tcaaaccagc caccgtcagg atgttctgtc
     4441 acgcaggcgt ccgccgacgt cgacggtggc gcgaactgat tcgaatagat ggcgggtaac
     4501 gcaaaggcgg tttccagatt gccgcccaga ctcagcagca ccacctgctc accttccgat
     4561 ggtcgccacc atgtgcgggc attcccggca cgcatcgtca gccagctgat ccagttggtt
     4621 tcaagctcgc ccgttttcac ccggcaaagc cagttttccc tgtccacttc ggtgactacc
     4681 cctgtgcgga tcaggttggt gataaggcgc atgatttcgg ttaattgtgc gttcataggg
     4741 aaaggttgcc atcaggggaa gaaaggcggc agtgctgcaa cttgtatcag tgctgataca
     4801 aagatcaccc cgccagccat tgcagaatca tgtcgcgggt cattgcctca acatcatcat
     4861 ttacacccag caggcggcgc tctgcgtaac ggacctccgg tcctttgcga ctgacgcgat
     4921 cacgcaggcc gtaatggtga acacgggcaa tacgctgcac cttgccttca aactgtacgc
     4981 tggcagagtc ggcgctggcg gcagttttca ggtattttgt ggtgcgcagc tttgcaaaca
     5041 tctgacgttt gatgcgcccc tttttactgc gtgctgttac ccgtcgcggc tcatagctgc
     5101 tgccgtcagg gttgcgctgc atcctgatat tctgctgctg tgtccggcgc agttcctgcg
     5161 ccagctggcg catcatgcgg cttctggcgg ctggttccag attcgccagc aaggcactca
     5221 gccagtcgtc cactttctgc agttcagcca cgtttcaccg tccacttttc ttcaggttca
     5281 tcgggttccg ctacagcttc aacgctcgac acactgccgt cagtgctgac cagcacacgt
     5341 tccgtcagtt gcaggttcag gctgatatca cagacatcgt tgcgcagaat atccacctca
     5401 aaggtgaata gtttttcccg taacgccggg ttattgatgg catcgggctg gttatccctc
     5461 agccacagca aaaccggggc catcagcaga ttctggtcgc cgctgaaatc ctcaatcacc
     5521 gcgttcaggg tgtaacggta ctcccacgac atggagctgg cccccgtggc aaccagcgaa
     5581 ccgttatcca caaacagatg cagtttgtcc gggttattgc ggacataagg caccgcttta
     5641 ttgagggcgt ggcgcaggga ttgtggtttg ttcactgttt cgctcctgac acgcaataat
     5701 catgtccact ttgtctgcac agaccgccca ggcggcctcc gtttcatcca gcaacgcgtc
     5761 cagatcaccg ttagtgcgcg gcgttgcctg ctccagccga cacggcgtca ctcgcggaca
     5821 accactgacg gtaagctgca cctccggtga gtgtcggacg ttcccgcagc cggataatgt
     5881 cagcaggcaa aggagtatca gcccagcggc gtaaatcctc gttctcacgt ttcagctcct
     5941 cgatccggtg ttgtcgttgt ctcagcagcg cgctggtctg ttctgcttcg gcatagagcc
     6001 gcgcctgctc ccggttattg gtttcagtca gaatggacag gctaataagc tggctgttgc
     6061 tctttgccag tgcctggctt ttgctctgca gctcgtctga ctgcgtgctg atggtctggc
     6121 tggcatcagc cagccgccac gtctgccagc ccagcgccgc cagtaataac gccagcacaa
     6181 ccagcagcaa ccggttcatg ctgctacctg ttgcgccatc tgattacggg tgatccagaa
     6241 ggcaataacg gtcagcagat aaaagaccag ggtaatagcc caccccgtcc aggcgagact
     6301 tacgacaatc agcaatcgca tcacccaact gataaatacg ttttcttttc gggtaattgt
     6361 cttcagcaaa gatgccctta actcctgcca gagcgggcta ttcttaatta acgcagccag
     6421 tgctaccgga attaccgccc atgtcagcaa acaggctacc caaacgccgg acgctgccag
     6481 taccggaaaa atcccctgcg gatacaccat tgctgcgatt aacaacgcca tccataacat
     6541 cagaaacagt ccgctgatta atttcttttt catttcagtt tgctccctgt aaacaccagg
     6601 ccatctcccg cgcacggcgg ttatccagcc cctgattaaa cacacctttt acataaaccc
     6661 agcgcggcaa ctgtcggcac gcatccgccc agcgccgctg attgagcaat ttcaccagcg
     6721 tggagctgca ggcattgcct gtccccacgt tgaaggcaaa cgacaccacc gagtcataca
     6781 ccttttgtgg cggctgttgc ttcacacacc tttccagcgc ccgctccaca cgcagcacgt
     6841 tggagataag cccttctgct gcctgtcgtt ccgtaatggt tttgccggga atgacgcccg
     6901 acgtattacc aatgccgtca gtccatacac ccgcgctgca ctgatacggc tgcagacgac
     6961 agccttcgta atcggcaatc agtttcagtc cttccacgga ggtgtgaagc tgctgaaaac
     7021 ccggcagcgt ggcagcaata gccagcacgg tcccgacaag gcagcgttta acgattgatg
     7081 gattcatagt cctcccgcgt gatctgcccg tcgcgcagaa gctggtaggc tttgtgtttg
     7141 tagtaccagt tgatagccag catcagcaca ccgatcatca ggccgcccag cgttgagata
     7201 tccttgatgg acaaatcgcc cagccaggcc agcacgacgg cgatgcaata cgtgataaag
     7261 gcgctgattc gctcaagcgt cataattcag tcccatagct ggacggtctg cacggtggtg
     7321 gttgccggaa tgtccggcag ctccacctgc agcccgtgag gtaaaaaggg gccgtattcg
     7381 gcaagccccg gatttgcctt cagtacctgc tccgtgacac cctgcgtgcg cccgtaatga
     7441 cgccagcaaa gcgcgtccac cgtgtcatac tgatgcgcac gcactttcat cagataagct
     7501 ccactgtgca gtgcggcgcg tcctgtaccc ggctgatggc ccagcgggcg tcacgccata
     7561 aatcaccgct ggcttccgcc agttcctcgc cccgcttcac accggatgcc gtggtgtcat
     7621 agtcctggta acgttcgttg agcatggcgc gtgcccagca gtaaaccgcg ttgaaatagt
     7681 gctgaatgcg ctcacttttg ccgtccagct gttccgccgg aacctctgcc agcgaggcat
     7741 accccagcat ctgctggcgt ctgcgaaact catacagctc tgcgttgacc tccgaaattg
     7801 ccgacagcgc aacctgcttt aaacgcggct gcgtcaccgt gccgtcagtg cgcatgacac
     7861 tgcgaaactc cgacaggtcc acatcaggcc agaacggcgt atttctgatg atttccgcct
     7921 gttccggtgc ctgttctggc gcaacaaact tcatgctgct ttctcctgaa ataaagggcg
     7981 gtggacgggg ttttgatgtg gcagtgcctt tcgccacccc gtgccgcccg tgcgcggggg
     8041 cacgttctgt cagcggctgt cattgcgcag tctgcgctcc agctgctgtt tgtctttttt
     8101 cacgccacag cggggatcga gctgtaacgc atggttgaga tgattaaggg cggacgccgg
     8161 attgttttca ctcaggacag cgccaatcgc tttatgcaga cgcgcccgtg actggtccgg
     8221 catatccata ccgtctgtca gctccagcgt ctgcagcaac agatcggcat caaagccggt
     8281 ggcggcaagc attgcgctct gggctgcatc tgccatttcc tctgccagca cggtctgcac
     8341 gttgcggtta cctaacggca tcacccagcc atgacgcagg gcgtgacgcc cgatctccag
     8401 cgccccagca taatctccgg catcaatgcg ccacagcatc acgtacatca gcacgtcatc
     8461 ctgctgtgcg cctccggcag ccaggacacc ctctgcccag tcggcgtact tcggcagcag
     8521 ctccaccttg atttccgctt ttttgaccgt ggactgaaca cccttgagac ggcggcggtc
     8581 ttccgccagt tgcagcagca tcaggtcata gcccgacgcg tggcgaacac tgccgccctc
     8641 gcgggcggcc tgttcagcct ggacgcgcag gcgatgctgc cgtgcgggac tcaggctcat
     8701 gaattacgct ccggtttctg ctgcagcggc gctgaaatcg ccaatctgga tgttttccac
     8761 cagtgcggcg cagcggtagt cctcaaccac ataggcttcg ttaacggatt caaaattttc
     8821 aatccggtca cgtttcgggt tgtcgataac tgaacggcga cgggtgtctt cctgccagta
     8881 gatggacagg ttatccagac gggtgatcag caatgcattc ggcgggaaga acggcgcacg
     8941 cacggcctgc aggcccccca tgcgcttctg actgatgatc atatcggcag ccagtttttc
     9001 actgttttcc tgctctttgt tgaccagcgg gaaatacttg tcagacagca gttcacgccc
     9061 gcaaatcacc accagatcgt catcgtcctg gtagaccacg tcgataagct cattgacggc
     9121 atccatcacc actgcgtcca ggttggcata ttcgccacct ttcccgactt tcaccgcacc
     9181 cggtgtggtt tcaccgcccg tggtggtgct gcccatgacg tgatccgatg catcctcacg
     9241 gattttctgc agccagcctt tgttcacatc ctgcagcagc gggttttcgc tacggttgga
     9301 ggttttcgca cgcttcacgc cgttaaagcc gatcatgatg cggtccagtg cctgacgttt
     9361 cacgatggcg tcacggatac gcacctggaa atcctgaaac ttcgcccaca ggtccagctt
     9421 cgcgtaggtc agcaccgtgt caaagttggt ctgctcgcat ttatattcca catcgaccat
     9481 cagcgtcgga tcgacaggct cacgctcttt cgcggaggta tcagtggttc ctgcaatggt
     9541 gctgccaacc cccaatccaa gcaactgacc ggactgttca gtcaccgggg tgacattaat
     9601 cagcgtcagg aaagcggcgg actgctggat ctggtcttcc agcgtctgct gtacagacgg
     9661 ctctacggtg aatttgctgg acagttcttc aacagccaca ccgttcagac gcgccagctg
     9721 ctgcaggtaa gcgttaaaag caaagcgggt attcttcttc atcaggtttt gtgctccatc
     9781 agcaattggt cagagtgtca gcgggggcgt taccgcctgt tgcacgctgg cggtagtcct
     9841 ggcggctgtc ttcatggctc agcttgtcca ccagttcgtt aaaggcggtc agctgtgcct
     9901 gcagggctgt ctccagctca gacaggcgtt cttcctgctc agacagggat ttttcggtgc
     9961 gtgcgctcag gttctgctgc tcagtggcga ccagctccac ggccttatgc acatcagcga
    10021 accgggcgtc atcggactgc tcttttttgg taaacagcgc cgtgacacgg gcaaacaggg
    10081 acggtttgtc gtcctggatt tcttccagtt cgatcaccgt ttcctctgca gcggtaaaga
    10141 gattggcagg attctgcttg cggtttgcca gtgggttatg ggctgcactg gcgctgaatg
    10201 tcagcatttc agtgcccaga ctggcagggt catcagtggc agccaggccg accaggtagg
    10261 ctttgcccgt atcagcaaac ttcgggctga cttccataga ggtgaataat ttctggcctt
    10321 ttttcaccag ttccaccagg gattccgttg gctcaacgtc ggcatacagc gccatcttgc
    10381 ctgccaacgg accttccgtg atttcttcag caaacagcgc cgtcaccttg ccgtagcggt
    10441 taaaggtgct gtccggcaga taagacttga tgtgttcaag gttaatcagc gcggtataca
    10501 ccgccgggtt gtagctggct gccatctgtt ccagccattc acgctggatt tcacgtccgt
    10561 cggtagtggc accttccacc ccgatgcgaa aacgctttgc tttcactgtc atgagccgtg
    10621 ctccgttaga aaaaacttac tggagcctta tggttgcggt gatgagggca gtgaaacaat
    10681 gcgcggtatt tgtaccgaca accacacaaa ccgcaggcgg ggaaagcctt cattcaagac
    10741 tgtaggtttg tgccatgaac accacactga cacccgcaga tctcgatccc cgtcggcagg
    10801 ccatgctgct gtactttcag ggataccgcg tcgcccgcat tgctgaaatg ctgggcgaga
    10861 aagttgcaac cgttcacagc tggaaaaaac gcgacaagtg gggtgactat gggccgctgg
    10921 atcagatgca gctcaccacc gccgcacgct actgccagct cattatgaag gagcacaaag
    10981 aagggaaaga tttcaaagag attgacctgc tggcgcgcca gtctgagcgc cacgcgcgga
    11041 tcggcaagtt taacaatggc ggcaacgaag ccgacttaaa ccctaacgtc gccaaccgca
    11101 acaaaggccc gcgccgtcag ccggaaaaaa atgtcttcac cgatgaacag attgagaagc
    11161 tggaagaaat cttccattcc tccatgttca actaccagcg ccactggtgg gaagccggaa
    11221 aaaccaaccg catccgcaac ctgctgaagt cacgccagat cggcgcgacc ttttactttg
    11281 cccgtgaagc cctgattgac gccctgctta ccgggcgtaa ccagattttc ctttccgcca
    11341 gtaaggcaca ggcccacgtc tttaagcagt acatcatcga cttcgccaaa gaagtggagg
    11401 tggagctgaa aggcgatccg atggtgcttc ctaacggggc cacgctttac ttcctcggca
    11461 ccaatgcccg cacggcccag agttatcacg gcaacctgta tctggatgaa tatttctgga
    11521 taccgaaatt tcaggagcta cgcaaagtgg cttccggtat ggctattcac aagaaatggc
    11581 ggcagaccta tttttccaca ccatccagtc tgacccacag tgcttatccg ttctggtccg
    11641 gtgcgctgtt caaccgtggg cgcaacaaag ctgacaaggt ggacatcgac ctgtcccaca
    11701 gcaatctggc ccccggcctg ctgtgcgcag acgggcaata ccgccagata gtcaccgtgg
    11761 aagatgcggt gcgcggtggc tgtaacctgt tcgacctcgg ccagttgcgc atggagtaca
    11821 gcccggacga ataccagaac ctgctgatgt gtgagttcgt ggacgatctc gcgtccgtgt
    11881 tcccgctcag cgagctgcag gcgtgcatgg tggacagctg ggaagtctgg accgactttc
    11941 atgcactggc gctgcgcccg tttggctggc gcgaagtgtg gatcggttat gacccggcaa
    12001 aaggtacgca gaacggcgac agtgccggat gcgtggtggt ggctccgcca gccgtgccgg
    12061 gtggtaagtt ccgcattctt gagcgtcacc agtggcgcgg gatggacttc cgcgcccagg
    12121 ctgacgccat caaaaaactc accgaacagt acaacgttac gtatatcggt atcgactcga
    12181 ccggcgttgg tcacggggtt tatgagaacg tgaaagcttt ctttcctgcc gtccgggagt
    12241 ttgtctataa ccccaatgtt aaaaatgccc tggtactcaa ggcctacgac attatcagcc
    12301 accgccgtct ggagtttgac gccggacaca ccgacattgc gcagtcattc atggcaatcc
    12361 gtcgcgcaac caccgccagc ggcaaccgcc cgacctatga agccagccgc agcgaagaag
    12421 ccagccacgc cgatctggcc tgggcaacaa tgcacgcact gtttaacgaa ccgctgcagg
    12481 gcgagtccgc caataccagc aatattgtgg agattttttg atgggaaaga gtaagaagaa
    12541 ccgcgctgcg tcgacgaacc agattcagca taaaagccag acttcagccg aagcattcag
    12601 cttcggtgat cccgttccag tacttgaccg ccgcgaactg ctggactatg tggaatgcgt
    12661 acagatggac cgctggtatg agccgcctgt gagtttcgac ggcctggcgc gaacattccg
    12721 cgccgccgta caccacagct caccgattgc agtaaagtgc aacattctga ccagcaccta
    12781 tatccctcac ccactgctca gccagcaggc tttttcacgt tttgtgcagg actatctggt
    12841 atttggtaac gcctacctgg agaaacgcac gaaccgcttc ggtgaagtta tcgcccttga
    12901 acctgcgctg gcaaaataca cccgacgcgg gttagacctg gatacctact ggtttgtgca
    12961 atacagcctg acgacacagc cgtatcagtt cacaaaaggt aacgtcttcc acctgatgga
    13021 gccggatatc aaccaggaga tttatggtct gccaggttac ctttctgcca ttccatccgc
    13081 cctgctcaac gagtccgcca cgctgttccg ccggaagtat tacattaacg gcagccatgc
    13141 gggcttcatc atgtacatga ccgacgccgc gcagaaccag gaggatgtga acaacctccg
    13201 caacgcaatg aaaagtgcca aaggtcctgg taacttccgt aacctgttta tgtactcgcc
    13261 taacggcaaa aaggacgggc ttcagatcat cccgttgtcg gaagtcgcgg cgaaggatga
    13321 atttctgaac atcaagaacg tgagtcggga cgacatgatg gcggcacacc gcgtaccgcc
    13381 gcaaatgatg ggtatcattc ccaacaacac tggcggcttc ggtgatgtgg aaaaggcgag
    13441 ccgtgttttc gtccgcaatg agctgatgcc actgcaaaag cgactgctgg agcttaacaa
    13501 ctggctgggt gaaaaggtga tccgttttga aacctatgac ttaggactta agagcaaacg
    13561 aggctgacat actcacaaca tcaataactg accaattctc acaacgcccc agcagcattc
    13621 tgcagggcgt ttctttttgt cctgacattt tccccctacg caaaatgagg ctgccagcgg
    13681 gccagaggct gcgccggatt ttggccattt taccccgttg cgcgcgctcg tatccccgcc
    13741 acgcctgccc gctttatgta gtggttttca tgcgcctgca tgacataagc aaaggcccgc
    13801 cattcctagc gggcctcagc taaaacgatc ctcaaacgat catgcggatt catgcggcat
    13861 agtcatgcac ttgtgtggtt acgaaggaat atagttgcga aaatcgatta aaatgcctta
    13921 agctctctta atcaacccct tatgcgttgc tttggtaaga taagctaatt ctttaggccc
    13981 cttatctcta aagcccaccc attctggttg gaattttata aaacttggaa ttgcggttgc
    14041 caaggctgta accataccgg gaataatacc gcctgaataa ccagcaatag cagcatggta
    14101 caacggtttt aaaaattcca taacctgccc accatctact tctggattgg ctttgactcc
    14161 cattctgata ggatttctcc atttcccttc gatagcttta tcaagattaa ctacagcctc
    14221 ttgtaataaa gaaaaatttt tagccctcgt tagattaggg tctctagaat aaaggacttc
    14281 agtatacagt ttttctaagt actcatgtaa cgcattaaga tcatcctgac aatcatcttt
    14341 aaaacgtaat atatcttcta tatgagcatc tttatcagga attctcagaa cattaaacaa
    14401 ctccaatctc aa
//
LOCUS       DAPHKZ010000115        14353 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.115, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000115 DAPHKZ010000000
VERSION     DAPHKZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14353
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.115"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(125..793)
                     /gene="artM"
                     /locus_tag="RH288_003597"
     CDS             complement(125..793)
                     /gene="artM"
                     /locus_tag="RH288_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HDV4032616.1"
                     /translation="MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVL
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            complement(793..1509)
                     /gene="artQ"
                     /locus_tag="RH288_003598"
     CDS             complement(793..1509)
                     /gene="artQ"
                     /locus_tag="RH288_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HDV4032617.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVA
                     WAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLL
                     SQYILKRIDLRATRFERRPS"
     gene            complement(1516..2247)
                     /gene="artJ"
                     /locus_tag="RH288_003599"
     CDS             complement(1516..2247)
                     /gene="artJ"
                     /locus_tag="RH288_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV4032618.1"
                     /translation="MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIV
                     GFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDGVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KLNTALEKVKKDGTYETIYNKWFQK"
     gene            complement(2265..2993)
                     /gene="artP"
                     /locus_tag="RH288_003600"
     CDS             complement(2265..2993)
                     /gene="artP"
                     /locus_tag="RH288_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HDV4032619.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQN
                     LIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGH
                     IVEQGDASCFTEPQTEAFKNYLSH"
     gene            complement(3211..3726)
                     /locus_tag="RH288_003601"
     CDS             complement(3211..3726)
                     /locus_tag="RH288_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV4032620.1"
                     /translation="MRYSKLTMLIPCALLLSACTTVTPAYKDNGTRSGPCVEGGPDNV
                     AQHFYDYRILHRSNDITALRPYLSDKLATLLSDASRDNNHRELLTNDPFSSRTTLPDS
                     AHVASASTIPNRDARNIPLRVDLKQGDQGWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
                     AGTLRQSIENR"
     gene            3852..4175
                     /locus_tag="RH288_003602"
     CDS             3852..4175
                     /locus_tag="RH288_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDV4032621.1"
                     /translation="MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTA
                     VKTRR"
     gene            4172..5002
                     /gene="amiD"
                     /locus_tag="RH288_003603"
     CDS             4172..5002
                     /gene="amiD"
                     /locus_tag="RH288_003603"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiD"
                     /protein_id="HDV4032622.1"
                     /translation="MRRFFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRI
                     KVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGI
                     SAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
                     ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDTASL
                     LELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
                     "
     gene            complement(4999..6012)
                     /locus_tag="RH288_003604"
     CDS             complement(4999..6012)
                     /locus_tag="RH288_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDV4032623.1"
                     /translation="MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMG
                     AEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
                     TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLA
                     SQEACDKLPSGRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMER
                     LGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAWLRDHGK
                     LPR"
     gene            complement(6111..7541)
                     /locus_tag="RH288_003605"
     CDS             complement(6111..7541)
                     /locus_tag="RH288_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HDV4032624.1"
                     /translation="MPQRILVLGASGYIGQHLVRTLSRQGHQILAAARHVDRLAKLQL
                     ANVSCHKVDLSWPDNLPALLQDIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVP
                     VKQLIFLSSLQAPPHEQSDHLRARQATADILREANVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPASEHRIFEAAGPEVLSYQQQ
                     FEHFMAVSGKRRWLIPIPLPTRWISVWFLNVITSVPPTTARALIQGLKHDLLADDTAL
                     RALIPQRLIAFDDAVRSTLKEEEKLVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKT
                     SASLAALWQVVNQIGGKERYFFGNILWQTRALMDRAIGHKLAKGRPEREYLQTGDAVD
                     SWKVIVVEPEKQLTLLFGMKAPGLGRLCFSLEDKGDYRTIDVRAFWHPHGMPGLFYWL
                     LMIPAHLFIFRGMAKQIARLAEQSTD"
     gene            complement(7552..8553)
                     /gene="ltaE"
                     /locus_tag="RH288_003606"
     CDS             complement(7552..8553)
                     /gene="ltaE"
                     /locus_tag="RH288_003606"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDV4032625.1"
                     /translation="MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAA
                     ELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQP
                     IDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERN
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAI
                     RWRKMAGGGMRQSGILAAAGMYALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTN
                     MLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSREQLAEVAAHWRAFLAR"
     gene            complement(8590..10308)
                     /gene="poxB"
                     /locus_tag="RH288_003607"
     CDS             complement(8590..10308)
                     /gene="poxB"
                     /locus_tag="RH288_003607"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HDV4032626.1"
                     /translation="MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEW
                     MSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKE
                     LVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQF
                     PYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDK
                     ALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
                     LPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVD
                     EALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            complement(10441..11409)
                     /gene="hcr"
                     /locus_tag="RH288_003608"
     CDS             complement(10441..11409)
                     /gene="hcr"
                     /locus_tag="RH288_003608"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HDV4032627.1"
                     /translation="MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYAL
                     VSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSQWLTRDVKRGDYLWLSDAMG
                     EFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVRVIYNVRTPQDVIFADEW
                     RNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKALG
                     VTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAG
                     VCGCCKTKVVSGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLVLA"
     gene            complement(11421..13073)
                     /gene="hcp"
                     /locus_tag="RH288_003609"
                     /gene_synonym="priS"
     CDS             complement(11421..13073)
                     /gene="hcp"
                     /locus_tag="RH288_003609"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDV4032628.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQG
                     LSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQC
                     LAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSIL
                     DAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRS
                     IVGWPGVRHLDGDDFSAVITQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA"
     gene            complement(13217..14116)
                     /gene="lysO"
                     /locus_tag="RH288_003610"
     CDS             complement(13217..14116)
                     /gene="lysO"
                     /locus_tag="RH288_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415395.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lysine exporter LysO"
                     /protein_id="HDV4032629.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFM
                     GISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRI
                     AMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
                     IVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMV
                     PAAIVHGFILSLLVPILIAFFSA"
BASE COUNT         3463 a         3840 c         3804 g         3246 t
ORIGIN      
        1 gcactatgta ggccggataa ggcgtccccg ccgcatccgg cacaggcacc gtgctgatgt
       61 ctgatgcgac gctggcgcgt cttatcagac ctacaaaacc ccccggcgaa tgtacgcagc
      121 cacattaatt tcgccgttcg aatgccagcg ctttgcgctc gatcagacgc atcatcagcg
      181 tcagcaggcc gttaacgacc aggtaaataa tccctgccgc accgaacacc attacatcgt
      241 aggtgcgtcc gtacaacaac tggctgtatc ccatcacttc catcagcgta atggtgtatg
      301 ccagagaggt acttttgaat accagcacca cttcgttgga ataagaagag agcgagcgtt
      361 taaaggcata cggcagcagg atcgccagcg tatctttttt gctcattccc agggcgctac
      421 aggactgcca ctgaccttcc gggatcgcac gaattgcacc gtaaaacagc tgcgtggtat
      481 acgccgcact attcagcgac aacgcaatca gcgcacataa ccacggttct gacaacaaat
      541 gccacagtgc cggatactcc tgcaaagtcg gaaactggcc cggcccgtaa taaatcagga
      601 agatctgcac cagcagcggc gtaccggtaa acagcgtgat ataaccccgc accagccaca
      661 ccagcaccgg cgttttcagc gtcaggatga tggtaaaaat caatgccaga atcagtgcca
      721 caatcagcga ggcaacggtt agcgtcaggc tggtgtgtag ccctttcatc agttcgggta
      781 aatactcaaa cattagctgg gcctccgctc aaaacgtgtc gcgcgcaggt caatgcgttt
      841 gagaatgtac tgactgagca gggtgatcac caggtaaatc gccgccgcca caatgtacca
      901 ggtaaatggt tcctgggtac gagtagcgat gctttttgtt tgcagcatta aatcattcac
      961 actaatcaaa ctgaccagcg cggtatcttt cagcagcacc agccactggt taccgaggcc
     1021 aggcagcgca tgacgccaca tctgcggcat caccagacgg aaaaagatag ccgatttcga
     1081 cagccccagc gcctgaccag actcccactg acccaccggc accgctttca acgcgccccg
     1141 aagcgtttgc gaggcatagg cggcatacag cagtgacaga gcgatgacac cacaaaggaa
     1201 cgggctaacg tcgaagttct caatgtccat ctgcactggg atctgcacga acccaagatt
     1261 gatagtgaag ccatccgaaa gcgtcagcag cagctgcgag gagccaaaat agataaacag
     1321 caccaccaga atttctggca ggccacgcag aatggttacc agcgctgaac ctgcccacgc
     1381 gacaggacgc cattttgccg actcccatac cgcaaagaac atcgccagcg ccagcccgac
     1441 aatcaatgca caaacggcaa ggccgacggt catcccggcg gcgcttgcta aaggaaaaaa
     1501 ttcattcatc aggaattact tctggaacca tttgttgtag atggtttcgt aagtgccatc
     1561 tttcttcact ttttccagcg cagtgttgag tttctgctgc agctcagtgt tgccctgacg
     1621 taccgcgatg ccgaggccag tgccgaagta atctttatcg gtcactttgt cgcccaccgc
     1681 cgccagtttc gggttatctt tcagccactc agtgaccact gcggtgtcac cgaagacgcc
     1741 gtcgatacgc ccgttttgca gatccagttt tgcgttctgg tagctgtcat acggaacggt
     1801 agtgatttcc gggtgcttat ccataatgaa tttctggtgt gtcgtcccgt tctgtacgcc
     1861 gacttttttg cctttcagct gatcaacact ggtgtatttg ccttgctgac ccacaaacag
     1921 ggcagagttg tcatagtacg gggtggtaaa cagcacctgc ttttcacgct ccggagtgat
     1981 atccatgccc gccatcacgg cttctacgcg acggaatttc aggcttggga tcaggctgtc
     2041 aaacgcctgg ttagagaaag tgcaggttgc atcaatctct ttacacagcg cttgtgccag
     2101 gtcgacgtca aaaccaacga tctggttgtt tgcatcaatc gattcaaacg gaggatagga
     2161 ggcttcggta gcaaaacgaa tggtttcggc agctgtggcg gaaagactaa aacctgcaat
     2221 taacgcggca atcagaactt ttttcattgt tgttatcccg aatcttagtg agagagatag
     2281 tttttaaatg cttcggtttg cggctcggta aagcagctcg cgtcgccttg ttctacgata
     2341 tgaccatttt ccatatacac cactcggctg gcggttttac gcgccacttc aacttcgtgg
     2401 gtgacgatca cctgggtaat attcgtttct gccagctcac gaatgatgct gacgatttgt
     2461 gccgtaattt ccgggtccag tgcggcggtc ggttcatcga acagcagtac ctgcggttcc
     2521 atcatcaacg cacgggcaat agcaacacgc tgctgctgac caccagaaag atgcagcggg
     2581 taacgatcgc tataaggttt gagacgcaga cgttccagca gtttttctgc acgggccagc
     2641 gcctgatctt tactcaaccc cagtacacgg cagggcgctt caatcaggtt ttgctgcacg
     2701 gtcagatgcg gccacaggtt gtattgctga aacaccatgc caacgttacg acgcaaatcg
     2761 cgaatcgctt tgtcagaggg tgttttggtg aaatcgaaat ggttgcctgc aatgttgagc
     2821 gtaccggagc gcggcatctc aagcagattg agtacacgca gcagcgagct tttacccgcg
     2881 ccgctggggc caagtaacac cagcgtttcg ccctgtgggc aatccagcgt gatatcgaac
     2941 agcgcctgat gcgcgccgta gaagcaatta atgccgttta attgaatact cattgacact
     3001 cgtatactgg cagtctgata gctattgagg tcgaagatag tacctttgac agaataatta
     3061 tgcaatattt ctgctttaaa agttaaaagc aaagcgcatt attcaataaa catagcacaa
     3121 aataacgggg gcggtggtcg gcgagcataa atgtcggcat tcctcacgaa atgccggaca
     3181 atttacgggg tttattggtt gatcaaggcg ttagcgattc tcgatggact gacggagcgt
     3241 acccgccgtg gcatgaacgc taccgcctaa gtaacgcaca tcgtcgatga cccaacactg
     3301 gccttcctga atcattaaca cttcatcctg ccaaccctgg tcaccctgtt tgagatccac
     3361 gcgcaatgga atgttacggg catcacgatt agggatagtc gatgcactgg caacgtgggc
     3421 gctatctggc aaggtggttc gactggagaa tggatcgttg gtcagtagtt cccgatggtt
     3481 attatcccgg gaggcatcgc taagcagtgt cgccagtttg tcgctcagat aagggcgcaa
     3541 ggcggtgatg tcgttgctgc ggtgcaaaat gcggtagtca taaaagtgct gggccacgtt
     3601 atccgggcct ccttcaacgc aaggaccact gcgtgtgccg ttatctttat aagctggagt
     3661 gactgtggtg caggcactga ggagcagtgc gcaggggata agcattgtca atttgctgta
     3721 gcgcataatg atttccttat aagcgatcgc tctgaaagcg ttctacgata ataatgatat
     3781 cctttcaata atagcgtatc agtctgataa tgcttttgag atcgaaggct tagcaaacaa
     3841 ggagatcgat catgcaattt tctacaaccc caactctgga aggccagacc atcgttgaat
     3901 attgcggtgt ggtgaccggc gaagcgattt taggtgccaa tattttccgt gatttctttg
     3961 ccggtatccg cgatatcgtt ggcggacgtt ccggtgcgta tgaaaaagaa ctgcgtaaag
     4021 cacgggagat cgcctttgag gaattaggct cccaggcgcg ggcgctgggg gccgatgccg
     4081 tcgtcggtat tgatatcgac tacgaaacgg tcgggcaaaa cggcagtatg ctgatggtta
     4141 gcgtcagcgg tacggcggtg aaaacgcgtc gatgagaaga ttcttctggc tggtcgctgc
     4201 cgctctgtta ttggcagggt gtgcaggcga aaaaggcatt gtcgagaaag agggatatca
     4261 gcttgatacc cgacgccagg cgcaggcggc gtatccgcgc attaaagtgc tggtgatcca
     4321 ctacaccgca gatgattttg atagctcgct ggcgacactg accgataagc aggtcagctc
     4381 gcattatctg gtccctgcgg taccaccgcg atacaacggt aaaccgcgca tctggcaact
     4441 ggtgccggaa caagaactgg cctggcatgc ggggattagc gcctggcgcg gggcaacgcg
     4501 ccttaacgac acctctattg gcattgagct ggaaaaccgt ggctggcaaa aatcggccgg
     4561 agtgaaatat tttgccccgt ttgaaccggc acagattcag gcgcttattc cactggcgaa
     4621 agatattatt gcccgttatc acatcaagcc ggaaaacgta gtggcacatg cggatatcgc
     4681 accgcagcgc aaagacgatc cggggccatt atttccctgg cagcaactgg cgcagcaggg
     4741 gattggtgcc tggccggatg cgcagcgggt taacttttac cttgccgggc gcgcgccgca
     4801 cacaccggta gataccgcgt cattgctgga gcttttggcg cgctacggtt atgacgttaa
     4861 acctgatatg acaccgcgcg agcagcggcg cgtgattatg gcattccaga tgcatttccg
     4921 cccgacgtta tataacggcg aagcggatgc agaaactcag gcgattgccg aagcattgct
     4981 ggagaaatac gggcaggatt agcgcggcag ttttccgtgg tcgcgtagcc aggcggcagt
     5041 tttctcgata ccttcatcca gggtgatgac cggctgataa cctaactctt cctgcgcacg
     5101 cgtaatatcc agcgtaaagt caaaattcaa cttggagacg ccgtagtggg tcagcggcgg
     5161 ctcttttgct gacttgcggc ctaaacgctc catgctgcgg gcgatcatat ccagcatcgg
     5221 gtaggggacg gaacgaatac gacagtcaat attcaactcg tcgatcagct tctgcacgat
     5281 gctgcgcagt gtgcgatgct cgccgttggt gatgttgtac acacgcccgg aaggtagctt
     5341 atcgcaggct tcctggcttg ccagccacat tgcgtgcacg gcattttcat agtaggtcat
     5401 atcgaccagc gcactgccgc catgcggtaa cagaatactg ccgtagtggt gcatcatatg
     5461 cgccagacgg ggaataaaga ctttatcgtg cggtccgaac agactttgtg ggcgcagaat
     5521 agtaaagcgc gtttgtggat tcgcctgcga aagcatattg atcacttctt cgctggctgc
     5581 tttgctgcgg gcaaactcgt tggcgaagcg gtgagggcga aaatcttctt taatatcgcg
     5641 atggtggtga taatcgaagt acagggaggg ggaagagata tgaataaagt tacgcacacc
     5701 ccaggcgaca gcccattcac ccaggcggcg agtggcgcga acgttagcca gatcgaaagc
     5761 ctgttgtgtc ccccagggtg aggtaaagct ggagcagtgc cacagcgtat caatgcccgc
     5821 gagcatcact ttagcttgtg atgaaaccag ctcggtcaga tccgccggaa caaactctgc
     5881 gcccattttt tccagcaatt tgcccattgc ctcgttgcga ccggtcgctc gcacgctgat
     5941 gcctttctgg cataaaaact ctaccgcgtt tcgacctaag ccgctggtgg cgccggtaac
     6001 cagtaccttc atatcaatcc actgttgttg agaaaataac gtgcgcattc ttccgtgatt
     6061 tcccccatga tgcaatggga aacatgaaag aataacgcag gttttgtcga ttaatctgtg
     6121 ctttgttctg ccagtctggc gatttgtttt gccattccgc gaaaaataaa cagatgcgcg
     6181 gggatcatca ataaccagta aaacagcccc ggcataccgt gcggatgcca gaaagcgcgg
     6241 acatcgatag tacgatagtc gcctttatct tccaggctaa aacacagtcg tcccagcccc
     6301 ggcgctttca tgccaaataa caacgtaagt tgtttttccg gttcaacgac aatcactttc
     6361 cagctatcca ccgcatcgcc agtctgtaaa tattcgcgct ccgggcggcc tttcgccagc
     6421 ttatgaccga tcgcgcggtc catcaacgcc cgtgtctgcc acaaaatatt gccaaagaaa
     6481 taacgctctt taccgccgat ttggttcact acctgccata aagcagcaag gctggcggac
     6541 gttttaacgg taaaccccgc ctgtttggca aaataaccgt actccggtcg ccagcgggca
     6601 aaggcctgag cgtcgtagcc ccagtcgctg gagttgacca gtttttcctc ctctttcaac
     6661 gtgctacgta ccgcgtcatc gaaagcgatc agccgttgtg ggatgagtgc acgtagcgcg
     6721 gtatcatccg ccagcagatc gtgtttcagc ccctgaatca acgccctggc ggtggtgggc
     6781 ggtacggaag taatcacatt gagaaaccac accgaaatcc agcgggtggg gagggggatg
     6841 gggatcaacc agcggcgctt accgctcacc gccataaaat gttcaaactg ttgctgataa
     6901 ctgagcacct ctggtccggc ggcttcgaag atgcggtgtt cgctggccgg atgatctaac
     6961 aacgccacca gatagtgcag caagttttcc agcgcgatgg gcgtggtgcg tgaacgtacc
     7021 cagcgtggcg gcgttaacac tggcaggttg tagaccatat cgcgcatgac ttcgaacgcc
     7081 gctgaacctg cgccaacgat aattccggcc cgaagttcgg tcacaggtac attcgcttca
     7141 cgaagaatgt ccgccgtagc ctgacgagca cgcagatgat ccgactgctc atgtggcggg
     7201 gcctgcaacg aactgagaaa gattaattgc ttaactggta cttcacgtag cgcatcgcgg
     7261 acgttgagag ccacctggcg ctcctgagcg ataaaatcgc cgccttcgcc catgctgtgc
     7321 accagaaaat agacggtatc gatatcctgc aacagggccg gaaggttatc cggccagctg
     7381 agatcgactt tatggcaact gacgtttgcc agttgcagct ttgcaagcct gtcgacatga
     7441 cgtgccgccg ccaggatctg atgcccttgc cggctgagtg tgcgcaccag atgctgacca
     7501 atgtagccac tggcaccgag aactaaaatg cgttgcggca cgtctctctc cttaacgcgc
     7561 caggaatgcg cgccagtggg cggcgacttc cgccagttgt tcgcgcgaga cgtcaagatg
     7621 cgtcaccagg cggacaatcg gcgaggcgtt aatcagcacg tttctcgctt tcatgtattc
     7681 gcctaacgcg gcagcatttt cttccccgac gcgaacaaac agcatattag tgtcctgacg
     7741 catcacatcc gcgcctgctt cacgcagttg ctccgccatc caggcggcgt tgtcgtgatc
     7801 ttcctgcaac cgtgcgacgt tatttttcag ggcatacatc ccggcggcag ccagaatccc
     7861 ggactgacgc atcccgccac cggccatttt ccgccagcgg atggcacgtt taatgtaatc
     7921 acgattaccg acgagtaatg aaccgactgg cgtcccaaga cctttcgaca ggcaaatggt
     7981 gaacgaatca caatattgcg tgatctcttt cagttcgcag ccgtaagcca ccacggcatt
     8041 aaagatgcgc gcaccgtcaa catgcagcgc cagattgcgc tcgcgggtaa attcccatgc
     8101 ttctttcagg tattcacgcg gcagcacttt gccgttgtgg gtgttttcca gactgagtaa
     8161 tttggtgcgg gcgaaatgga tatcgtcggg tttgattttc atcgccactt tatccagcgg
     8221 tagcgtgccg tcggcagccg cgtcgatggg ttgcggctga atactgccca gcaccgctgc
     8281 gccaccggct tcaaacagat agttatgcgc ggcctgaccg acaatatact cttcgccacg
     8341 ttcgcagtga ctgagcagag cgaccaggtt ggcctgagtg ccggtaggca gaaaaatggc
     8401 ggcttcttta ccggaaagct ctgctgcgta gtcctgcaga gcattaacgg tagggtcgtc
     8461 tccgtaaacg tcgtccccaa ccggggcggc catcatcgct tcgagcatgg cgcggcttgg
     8521 tcgggtaacg gtatcactgc gtaaatcaat catggcatgt ccttattatg acgggaaatg
     8581 ccaccctttt taccttagcc agtttgtttt cgccagttcg atcacttcat caccgcgtcc
     8641 gctgatgatt gcgcgcagca tatacaggct gaaacctttg gcctgttcga gtttgatctg
     8701 cggtggaatg gctaactctt ctttggcgac caccacatcc accaacaccg gaccgtcgat
     8761 ggagaaggcg cgttgcaggg cttcatcaac ttcagacgct ttttctacac ggatacccgt
     8821 aatgccgcac gcttcggcaa tgcgggcaaa gtttgtgtcg tgtagttcgg tgccgtcagt
     8881 caaatagcca ccagctttca tctccatcgc cacaaagccc agcacgctgt tgttaaagac
     8941 gacaattttc actggcagtt tcatctgcac tactgagagg aaatcgccca tcaacatgct
     9001 aaaaccgcca tcgccgcaca tggcgaccac ctgacgttct ggctctgtcg cctgcgcacc
     9061 cagcgcctgc ggcatggcgt tagccatcga accgtggtta aacgaaccta acaggcgacg
     9121 cttgccgttc atttttagat aacgtgccgc ccacaccgtt ggcgtaccaa cgtcacaggt
     9181 gaaaatagcg tcatcggcgg caaaatgact aatttgctgc gccagatatt gcgggtgaat
     9241 ggctttctcg ctcggtttag ctaaatcgtc cagccctttg cgggcgtcgc ggtaatcttc
     9301 cagcgcttta tccagaaact tgcgatcggc tttttcttcc accaatggaa gcaatgcacg
     9361 cagagtcgac ttgatatcgc cgaccagtgc catatccacc ttgctgtgag cgccgatgct
     9421 ggctgggttg atatcaatct gaatgatttt ggcatcggtc gggtagaagg cgcggtaggg
     9481 aaattgcgtg ccgagtagca ctaacgtgtc ggcgttcatc atggtatgga aacctgacga
     9541 gaagccgatt aacccggtca ttccaacatc atacggatta tcgtattcga catgttcttt
     9601 accgcgcagg gcatgaacaa taggcgcttt aattttcccg gcaaactcaa ctaactcttt
     9661 atgcgccccc gcgcagccgc tgccacacat cagggcgata ttgctggaat aacgcagcag
     9721 ttgcgccagt ttgcgtaact cttcttcttc cggcgtcacg actggttgtg gcgcatgata
     9781 ccagtgcatg gttgcccctt ctggcgcagg ttttaacgcc acgtcgcctg gtaacacgac
     9841 aaccgaaacg ccacggttaa gcaccgcttt gcgcatggca atcgccagta cttgtgggat
     9901 ctgctccggg ctggaaacca gctcgcaata gtgactacat tcgcggaata gctcttgtgg
     9961 gtgggtttcc tggaaatagc cgctgccaat ttcgctggag ggaatatgag cggcaatcgc
    10021 cagtaccgga acgtgattgc ggtggcaatc gaacaggccg ttgattaagt gcaggttgcc
    10081 ggggccgcac gatccggcgc agaccgccag ttctccgcta agttgtgctt cagcgccagc
    10141 ggcaaaggcc gccacttctt cgtggcgggt ggacatccac tcgatggtgc ccatgcgatt
    10201 aagactgtca ctaagaccgt tcagagagtc gcctgtgact ccccagatgc gtttcacccc
    10261 tgccgattcg agtgttttgg cgatataagc tgcaaccgtt tgtttcatgg ttctccatct
    10321 cctgaatgtg ataacggtaa caagtttagt tcatctgacg gagggggaag ggatgggaga
    10381 gaaaggaggc actaacggtt aaatagcccg atgaaaggaa tatcatcggg cataaggcga
    10441 ttatgcgaga accaaatccc cctgcggatg gcaggagcag gccagtacgt aaccttcagc
    10501 gatttcggcg tcggtcagcg tcattgtgct gctcaccgta tattcaccgg aaaccacttt
    10561 tgtcttacag cagccgcaaa cacccgcacg gcaggcagcg acaaccggaa cgttattgct
    10621 ttccagcgcc tccagtagcg tggtgccaac cggggcgtaa aattctcgtg ccggttgcag
    10681 tttggtgaat ttcagaccgc tggtcgccgc ttctgctact ggggtgaaga atttctcttt
    10741 aaagaaacgc gtcacgccga gcgctttcac ttcctgctct acccaatcca tatacggagc
    10801 cgggccgcag gtcatcacgg tacgtgaagc taagtcaggt acacctgcca gcagttcgcg
    10861 agtgagacga ccagcgataa agccttcggt aacgttattt tctgccacca gcgttaccgg
    10921 atagttacgc cactcatcgg cgaaaataac atcctgcggc gtacgcacgt tgtagatcac
    10981 ccgcacatcg gcctgtggac ggttcttcgc aagccagcga cgcatcgaca taatcggcgt
    11041 gacgccgcag cctgccgcca gcaacaggaa tttatcttct gctttatcgt cgcaggtaaa
    11101 ttcccccatc gcgtccgaaa gccagagata atcaccgcgt tttacatcgc gcgtcagcca
    11161 ctgggagccg acaccgtcat caatccgccg cacggtcagg gtgatatatt cactcacgcc
    11221 tggcgtggag gaaatggtgt aagcacgcag cgtttccgct gagtttcgca cgctgaccag
    11281 tgcatattgc ccggcgcgat atgggtagta atcgtggcaa atcagggaaa tcgtccacac
    11341 atccggcgtt tcttgcgtaa tgtgatgaac ctgcatccgc cacgggcatt gattcgttgg
    11401 catcgtcatc gacaaactcc ttacgcgctc aacagttgct tcatgtcttc ttcaacagtg
    11461 gtgatagaac gcaggccgaa tttctcgttc agcaccgcca gcaggtctgg tgtcaggaaa
    11521 ccaggtgcag tcgggccggt gacgatattt ttcacgccca gagaaagcag cgtcagcaga
    11581 atgacgatcg ctttctgttc aaaccaggag agcaccagcg acagcggcag atcgttgaca
    11641 ccgcagccca gtttctctgc cagagtgaca gccagaataa tcgctgagta agcatcgtta
    11701 cattgacctg catctaccag acgcggcaga ccttcgatat cgccaaactc aagtttgtta
    11761 aagcgatatt taccacaggc gagggtcagg atcaggcagt catccggcac gctggtggcg
    11821 aaatcggtga agtagtggcg ctcgccgcgt gcgccgtcac agccaccaag caggaagata
    11881 tgacgcagtt tttcacggct caccagatca atcagcgtat cagcagcgcc aagcagcgtc
    11941 tggcgaccaa aacccacggt gataaggtgc ggaatttcgc tgtacgggaa gcctgccatc
    12001 tgttgcgcct gggtgataac cgcagagaaa tcatcaccgt ccagatgacg cacgccaggc
    12061 cagccaacaa tgctgcgggt ccagatacga tcgtcataag cgcctacggt tgggtcgatg
    12121 atgcagttcg aggtcatcac gatggggcca gggaaacgag cgaactccac ttgctgattc
    12181 tgccagccgc tgccgtagtt accgaccaga tgcttgaatt tacgcagctc cgggtagcca
    12241 tgcgcaggca gcatttcgcc gtgggtgtag acattaacgc ccgtgccttc ggtctgttcc
    12301 agcaggttgt agagatcttt gagatcgtga ccggaaatca gaatgcattt acccgccgtc
    12361 gctttgacgt tgacctgggt tggcgtcggg tgaccgtatt taccggtttc gcctgcatcc
    12421 agaatgctca tcactttgaa gttcatctgg ccgatttcca ttgaacactc aagaagcgcg
    12481 ttcatatcgg caggccaggt ccccagccac gccatgattt tatggtactg ggcataaata
    12541 tcgttgtcgt attgaccgag aacatgcgcg tgttccatat aggccgccgc acctttcagg
    12601 ccatacaggc acagcagacg caggccgaga atgttttcgc caatcgccgc tttatctttg
    12661 ttaggggtaa attctgctgc ctgacgttgc agctcgccga gatcgtcgct caccagttgc
    12721 aggtcagcca tcgggttatc gacgcgcgcg ttggcatcta cagccaggca ttgcgctttc
    12781 agcgcctcgc gcagggcaat cgcttcacga gcgtagccga caatacgcgg agaatcgaag
    12841 ttaacgttgg tcagggttga gaaaaaggca cgtggcgcga agctgtcaac atcgtggttg
    12901 atgatgccgt attcacgcgc ttttaccgcc caggcagaaa gcccttgcag cgccgcgatg
    12961 agtaaatcct gaaggtcaga agtttccgcc gttttaccac acatcccctg cgcgtatgag
    13021 cagccgtttc ctgccggagt acggatagtt tgttcacatt gcacacaaaa catgatcaca
    13081 ccttttaaag ttatatttaa tatacatgtt taaggttaag acgcttaacg cggggataaa
    13141 agggattttt catgcaactt taagggagat tgatttagcg caattttggc ggcagggatc
    13201 taccgccaga gaggtattac gcagagaaaa aggcgatgag gatcggcact aacaggctaa
    13261 gaataaaacc gtgaacaatt gccgccggga ccatatccag cccgccagta cgttgaagaa
    13321 cgggcagggt gaaatccatt gatgtggcac cgcataagcc cagtgcagta gagcggctgc
    13381 ggcgaatcag cccagggatc aacataatag caatcagttc acgggccaga tcattaaaaa
    13441 acgccgcgct cccgattacc ggaccaaaag attcggtcaa taaaataccg gaaagagaat
    13501 accagccgaa accggaggcc attgccagcg cggtattgat ggggagatca agaataaagg
    13561 cgttaattaa accaccaatt aatgaactga caaccaccac cacggcgaca atcattcccc
    13621 ggcgattaag gacaatctgc tttaaggtca tgccattatt gcgcaactga ataccaacga
    13681 ggaaaagtag caaaattaac gtgtattcac tggcttcggt cgcgtgttgt aagaaagcca
    13741 gtccacttag accaatggca aaaccaatca ctactacgcc gcacagtttt agcgactcca
    13801 gcgccatcgc aatacgcgac gggagttttt cttgctgatg gtggttgcgc cacggcaggc
    13861 ctcgctccag ccacatcagg gcggcaatat tacacagtaa aataacggta atactgacgg
    13921 cagaataatg cagaatcgcc aacaggttac tggcgaggtt atcgagaaac gccagactga
    13981 tacccataaa aaagagaata aggtaaacca tccagcttaa tagctgatta ataactttta
    14041 acgcagcttg ttggcgaagc ggaatgaggt aacccacaat caggggaacc agaatgatta
    14101 acagcccaga aaacatgaaa acccagtcct tgcaaagatg aagtcgaaat gcgcgatgac
    14161 acactactga aagcggaagg acgagtaaag ttgcaattaa aaggaaatgt tatgcataag
    14221 gagcagtaga gtattcgttt tcatttaaag atattcttgc gctttaatta caaactgcac
    14281 cgatgttggt ggcgtcaaaa tcgccgaggc gttccctgaa ggccggggca gcccacatgg
    14341 atgtgggctg agg
//
LOCUS       DAPHKZ010000116        14134 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.116, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000116 DAPHKZ010000000
VERSION     DAPHKZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14134
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.116"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..660
                     /gene="gspC"
                     /locus_tag="RH288_003611"
     CDS             <1..660
                     /gene="gspC"
                     /locus_tag="RH288_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HDV4032630.1"
                     /translation="TNAFQSDFSLAALWRNENHAGVKDANPVAVNQETPKLSIALNGI
                     VLTSNDETSFVLINEGSEQKRYSLNEALESAPGTFIRKINKTSVVFETHGHYEKVTLH
                     PGLPDIIKQPDSESQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIA
                     LRINNLSLTHPDEVSQALSLLLTQQSAQFTIRRNGVPRLINVSVGELTGMNGLRHERT
                     Q"
     gene            644..2596
                     /gene="gspD"
                     /locus_tag="RH288_003612"
                     /pseudo
     CDS             644..2596
                     /gene="gspD"
                     /locus_tag="RH288_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417784.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
     gene            2606..4087
                     /gene="gspE"
                     /locus_tag="RH288_003613"
     CDS             2606..4087
                     /gene="gspE"
                     /locus_tag="RH288_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HDV4032631.1"
                     /translation="MRIHSPYPASWALAQRIGYLYSEGEIIYLADTPFERLLDIQRQV
                     GQCQTMTSLSQADFEARLEAVFHQNTGESQQIAQDIDQSVDLLSLSEEMPANEDLLNE
                     DSAAPVIRLINAILSEAIKETASDIHIETYEKTMSIRFRIDGVLRTILQPNKKLAALL
                     ISRIKVMARLDIAEKRIPQDGRISLRIGRRNIDVRVSTLPSIYGERAVLRLLDKNSLQ
                     LSLNNLGMTAADKQDLENLIQLPHGIILVTGPTGSGKSTTLYAILSALNTPGRNILTV
                     EDPVEYELEGIGQTQVNTRVDMSFARGLRAILRQDPDVVMVGEIRDTETAQIAVQASL
                     TGHLVLSTLHTNSASGAVTRLRDMGVESFLLSSSLAGIIAQRLVRRLCPQCRQFTPVS
                     PQQAQMFKYHQLAVTTIGTPVGCPHCHQSGYQGRMAIHEMMVVTPELRAAIHENVDEQ
                     ALERLVRQQHKALIKNGLQKVISGDTSWDEVMRVASATLESEA"
     gene            4084..5280
                     /gene="gspF"
                     /locus_tag="RH288_003614"
     CDS             4084..5280
                     /gene="gspF"
                     /locus_tag="RH288_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HDV4032632.1"
                     /translation="MNYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQ
                     KSSGVKTRRPRISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNKRLGDVLNQVR
                     SAILEGHPLSDALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKL
                     IQSLIYPCMLTTVAIGVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRTG
                     PTLLATVFIVAVGFWLWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQS
                     SGVPLLDGMNLSTESLNNLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVAS
                     GEKSGQLGTLMVRAADNQETLQQNRSALMLSIFEPALIITMALIVLFIVVSVLQPLLQ
                     LNSMIN"
     gene            5290..5727
                     /gene="gspG"
                     /locus_tag="RH288_003615"
     CDS             5290..5727
                     /gene="gspG"
                     /locus_tag="RH288_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HDV4032633.1"
                     /translation="MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQK
                     AVSDIVALENALDMYKLDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADP
                     WGNDYVLVNPGEHGAYDLLSAGPDGEMGTEDDITNWGLSKKKK"
     gene            5735..6244
                     /gene="gspH"
                     /locus_tag="RH288_003616"
     CDS             5735..6244
                     /gene="gspH"
                     /locus_tag="RH288_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HDV4032634.1"
                     /translation="MNQQRGFTLLEMMLVLALVAITASVVLFTYGREDVASTRARETA
                     ARFTAALELAIDRATLSGQPVGIHFSDSAWRIMVPGKTPSAWRWVPLQEDAADESQND
                     WDEELSIHLQPFKPDDSNQPQVVILADGQITPFSLLMANAGTGEPLLTLVCSGSWPLD
                     QTLARDTRP"
     gene            6241..6618
                     /gene="gspI"
                     /locus_tag="RH288_003617"
     CDS             6241..6618
                     /gene="gspI"
                     /locus_tag="RH288_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417789.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HDV4032635.1"
                     /translation="MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQRNAIERMRNET
                     LALWIADNQLQSQDSFGEENTSSSGKELINGEEWNWRSDIHSSKDGTLLERTITVTLP
                     SGQTTSLTRYQSIDNKSGQAQDD"
     gene            6611..7198
                     /gene="gspJ"
                     /locus_tag="RH288_003618"
     CDS             6611..7198
                     /gene="gspJ"
                     /locus_tag="RH288_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HDV4032636.1"
                     /translation="MINRQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKE
                     IQQFNQLQRTITILDNDLLQLVARRNRSTDKIMVLGEEAIFTTQSRDPLAPLSEAQTL
                     LTVHWYLRNHTLYRAVRTSVDGRKDQPAQAMLEHVESFLLESNSGESQELPLSVTLHL
                     QTQQYGGLQRRFALPEQLAREESPAQTQAGNNNHE"
     gene            7191..8174
                     /gene="gspK"
                     /locus_tag="RH288_003619"
     CDS             7191..8174
                     /gene="gspK"
                     /locus_tag="RH288_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HDV4032637.1"
                     /translation="MNNEQRGVALLIVLMLLALMAALAADMTLSFHSQLQRTRQVNHH
                     LQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQH
                     CFNLNALAKISDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSPRF
                     HGAEDSFYQSQTPPRHSANQMLFLTGELRQIKGITENIYQRLIPYVCVLPTTELSINL
                     NMLTENDIPLFRALFLNNITDADARVLLQKRPREGWLTTDAFLYWAQQDFSGVKPLVA
                     QVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQQSAQIYRRTLQLY"
     gene            8189..9352
                     /gene="gspL"
                     /locus_tag="RH288_003620"
     CDS             8189..9352
                     /gene="gspL"
                     /locus_tag="RH288_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HDV4032638.1"
                     /translation="MPESLMVIRSSSTLRKHWEWMTFSADSVSSVHTLTDDLPLESLA
                     DQPGAGNVHLLIPPEGLLYRSLTLPNAKYKLTAQTLQWLAEETLPDNTQDWHWTVVDK
                     QNESVEVIGIQSEKLSRYLERLHTAGLNVTRVLPDGCYLPWEVDSWTLVNQQTSWLIR
                     SAAHAFNELDEHWLQHLAAQFPPENMLCYGVVPHGVAAANPLIQHPEIPSLSLYSADI
                     AFQRYDMLHGIFRKQKTVSKSGKWLARLAVSCLVLAILSFVGSRSIALWHTLKIEDQL
                     QQQQQETWQRYFPQIKRTHNFRFYFKQQLAQQYPEAVPLLYHLQTLLLEHPELQLMEA
                     NYSQKQKSLTLKMSAKSEANIDRFCELTQSWLPMEKTEKDPVSGVWTVRNSGK"
     gene            9349..9810
                     /gene="gspM"
                     /locus_tag="RH288_003621"
     CDS             9349..9810
                     /gene="gspM"
                     /locus_tag="RH288_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspM"
                     /protein_id="HDV4032639.1"
                     /translation="MIKSWWAEKSTSEKQIVAALAVLSLGVFCWLGVIKPIDTYIAEH
                     QSHAQKIKKDIKWMQDQASTHGLLGHPALTQPIKNILLEEAKRENLAITLENGPDNTL
                     TIHPVTAPLENVSRWLTTAQVTYGIVIEDLQFTLAGNEEITLRHLSFREQQ"
     gene            9810..10487
                     /gene="gspO"
                     /locus_tag="RH288_003622"
     CDS             9810..10487
                     /gene="gspO"
                     /locus_tag="RH288_003622"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase GspO"
                     /protein_id="HDV4032640.1"
                     /translation="MTMLLPLFILVGFIAGYFVNAIAYHLSPLEDKTALTFRQVLVHF
                     RQKKYAWHDTVPLILCVAAAIACALAPFTPIVTGALFLYFCFVLTLSVIDFRTQLLPD
                     KLTLPLLWLGLVFNAQYGLIDLHDAVYGAVAGYGVLWCVYWGVWLVCHKEGLGYGDFK
                     LLAAAGAWCGWQTLPMILLIASLGGIGYAIVSQLLQRRTITTIAFGPWLALGSMINLG
                     YLAWISY"
     gene            complement(10516..10992)
                     /gene="bfr"
                     /locus_tag="RH288_003623"
     CDS             complement(10516..10992)
                     /gene="bfr"
                     /locus_tag="RH288_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HDV4032641.1"
                     /translation="MKGDTKVINYLNKLLGNELVAINQYFLHARMFKNWGLKRLNDVE
                     YHESIDEMKHADRYIERILFLEGLPNLQDLGKLNIGEDVEEMLRSDLALELDGAKNLR
                     EAIGYADSVHDYVSRDMMIEILRDEEGHIDWLETELDLIQKMGLQNYLQAQIREEG"
     gene            complement(11064..11258)
                     /gene="bfd"
                     /locus_tag="RH288_003624"
     CDS             complement(11064..11258)
                     /gene="bfd"
                     /locus_tag="RH288_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HDV4032642.1"
                     /translation="MYVCLCNGISDKKIRQAVRQFSPHSFQQLKKFIPVGNQCGKCVR
                     AAREVMEDELMQLPEFKESA"
     gene            complement(11427..14120)
                     /gene="chiA"
                     /locus_tag="RH288_003625"
     CDS             complement(11427..14120)
                     /gene="chiA"
                     /locus_tag="RH288_003625"
                     /EC_number="3.2.1.14"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chitinase/lysozyme"
                     /protein_id="HDV4032643.1"
                     /translation="MKLNIFTKSMIGMGLVCSALPALAMEAWNNQQGGNKYQVIFDGK
                     IYENAWWVSSTNCPGKAKANDATNPWRLKRTATAAEISQFGNTLSCEKSGSSSSSNSN
                     TPASNTPANGGSATPAQGTVPSNSSVVAWNKQQGGQTWYVVFNGAVYKNAWWVASSNC
                     PGDAKSNDASNPWRYVRAATATEISETSNPQSCTSAPQPSPDVKPAPDVKPAPDVQPA
                     PADKSNDNYAVVAWKGQEGSSTWYVIYNGGIYKNAWWVGAANCPGDAKENDASNPWRY
                     VRAATATEISQYGNPGSCSVKPDNNGGAVTPVDPTPETPVTPTPDNSEPSTPADSVND
                     YSLQAWSGQEGSEIYHVIFNGNVYKNAWWVGSKDCPRGTSAENSNNPWRLERTATAAE
                     LSQYGNPTTCEIDNGGVIVADGFQASKAYSADSIVDYNDAHYKTSVDQDAWGFVPGGD
                     NPWKKYEPAKAWSASTVYVKGDRVVVDGQAYEALFWTQSDNPALVANQNATGSNSRPW
                     KPLGKAQSYSNEELNNAPQFNPETLYASDTLIRFNGVNYISQSKVQKVSPSDSNPWRV
                     FVDWTGTKERVGTPKKAWPKHVYAPYVDFTLNTIPDLAALAKNHNVNHFTLAFVVSKD
                     ANTCLPTWGTAYGMQNYAQYSKIKALREAGGDVMLSIGGANNAPLAASCKNVDDLMQH
                     YYDIVDNLNLKVLDFDIEGTWVADQASIERRNLAVKKVQDKWKSEGKDIAIWYTLPIL
                     PTGLTPEGMNVLSDAKAKGVELAGVNVMTMDYGNAICQSANTEGQNIHGKCATSAIAN
                     LHSQLKGLHPNKSDAEIDAMMGTTPMVGVNDVQGEVFYLSDARLVMQDAQKRNLGMVG
                     IWSIARDLPGGTNLSPEFHGLTKEQAPKYAFSEIFAPFTKQ"
BASE COUNT         3616 a         3648 c         3388 g         3482 t
ORIGIN      
        1 acaaacgcat ttcagtctga tttcagcctt gccgctttat ggcgtaacga aaatcatgct
       61 ggggtaaaag atgcaaatcc cgtggcagtt aatcaggaaa cacctaagct ctctatagcg
      121 cttaatggca ttgtactcac atcgaatgat gagacttctt ttgtcttaat taatgagggg
      181 agcgaacaaa agcgatactc cctcaacgaa gcccttgagt cagcgccggg aacgtttatt
      241 agaaaaataa ataaaaccag cgttgtgttt gaaactcacg ggcattacga aaaagtaact
      301 ctccatccag ggctacctga catcatcaag cagcctgatt cagaaagtca aaatgtactc
      361 gctgattata ttatcgccac gcctatacgt gatggagaac agatatacgg gcttcgattg
      421 aaccctcgta agggcctcaa tgcatttacc accagcttgc tacaaccagg ggatatcgcc
      481 ctcaggatca ataatctttc gctgacccac cctgatgagg tttcacaggc attaagttta
      541 ctgctaactc aacaaagtgc tcagtttaca attcgtcgca acggcgtacc ccgcttgata
      601 aatgtttccg tcggggaact tacaggaatg aatggactgc gtcatgaaag gactcaataa
      661 aatcacctgc tgcttgctgg cagcactact catgccttgt gcaggacacg ctgagaacga
      721 acaatacggc gcgaacttca ataacgccga tatccgccag ttcgtggaaa tagtgggtca
      781 gcatcttggc aaaacgatcc tgatcgaccc ttcggtacag ggaaccattt ccgtacgcag
      841 taatgatacg tttagccaac aggagtacta ccagttcttt ttaagtattc ttgatcttta
      901 cggttattcc gtgatcacgc tggacaatgg ttttctgaaa gtggttcgct cagctaatgt
      961 aaaaacatcg ccagggatga ttgctgacag ttctcgtcca ggcgtaggtg atgagttggt
     1021 cacccgaatt gtaccgcttg agaacgttcc tgctcgtgac ctggcccccc tgctccgcca
     1081 gatgatggat gcgggtagcg tcggtaatgt tgtgcattat gaaccctcca acgttcttat
     1141 tctgaccggt cgtgcctcca ccattaataa actgattgaa gtcataaagc gcgttgatgt
     1201 catcggcaca gagaagcagc aaattattca tctggaatat gcgtcagcgg aagatctcgc
     1261 cgagattctt aatcaattaa tcagcgaaag ccacggtaaa agccagatgc cagccctcct
     1321 ctccgcgaag attgtggcgg ataagcgaac caactctctt atcatcagtg gaccggaaaa
     1381 agcacgccag cgcatcactt cattactgaa aagccttgat gtcgaagaga gcgaggaagg
     1441 aaatacccgg gtttattacc tgaaatatgc taaagccacg aatctggtgg aagtgctaac
     1501 cggtgtttcc gaaaagctga aagatgaaaa agggaatgcg cgtaagccct cctcttctgg
     1561 cgcgatggat aacgtcgcca ttaccgccga tgaacagact aactctctgg tcattaccgc
     1621 tgaccagtcc gtccaggaaa aactcgccac ggtaattgcg cgtctggaca ttcgccgtgc
     1681 acaggtgctg gttgaggcaa tcatcgttga agttcaggat ggaaatggac taaacctcgg
     1741 cgtgcaatgg gcgaataaaa acgttggcgc acagcaattt accaataccg gattaccgat
     1801 ttttaacgct gcgcaaggtg tggctgatta taaaaagaat ggtgggatca ccagcgcgaa
     1861 tcctgcctgg gatatgttta gcgcctacaa tggcatggcc gcaggcttct tcaatggcga
     1921 ctggggagta ctgcttaccg cgctggccag taacaataaa aatgacatcc tcgccacccc
     1981 aagcatcgta acgctggata ataaactcgc gtccttcaac gtggggcagg atgtgccggt
     2041 gctatccggg tcacagacca cttcagggga taacgtcttt aataccgtcg aacgcaaaac
     2101 ggtggggaca aaactcaaag ttactccgca ggtcaatgaa ggcgacgcgg tgttgctcga
     2161 aatagagtag gaagtctcca gcgttgactc ttcctctaac tcgacgctcg gcccgacgtt
     2221 taatacccgt actattcaaa acgccgtgct ggtcaaaacc ggtgaaacgg tggtcctggg
     2281 cggattgctg gatgattttt ctaaagagca agtgtcaaag gttcctctgc ttggcgatat
     2341 tcctttagtg gggcaactct tccgctatac ctccaccgag cgcgctaaac gcaacctgat
     2401 ggtatttatc cgtccgacga ttatccgtga cgatgatgtt tatcgctcac tgtcaaaaga
     2461 gaaatacacc cgttaccgtc aggagcaaca acagcggatc gacgggaaat caaaagcgct
     2521 ggttggctcg gaagatttgc cggtgctgga tgaaaacacg ttcaacagtc acgcccctgc
     2581 gccatcgtca cggtgaggca ttcatatgag aattcactca ccgtaccccg ccagttgggc
     2641 gctggcacaa cgaattggtt atctctattc agagggcgag attatttatc tcgccgatac
     2701 gccattcgag cggttactcg atattcaacg tcaggttggc cagtgccaga ccatgaccag
     2761 cttgtcacag gctgattttg aagctcggct ggaagcggta ttccatcaga ataccggtga
     2821 gtcgcaacag attgcgcagg atatcgatca atccgtcgat cttctctcgc tttcggaaga
     2881 gatgcccgca aatgaagatc tcctgaatga agattcagcg gcaccggtta tccgcttgat
     2941 caatgcgatt ttgagtgagg ccatcaaaga aaccgcctct gatatccaca ttgaaaccta
     3001 tgaaaaaaca atgtcgatcc gttttcgcat cgacggcgtt ttgcggacaa ttttacagcc
     3061 aaacaaaaaa ctggcggcac tgcttatctc ccgaattaag gtcatggctc gtcttgatat
     3121 cgccgaaaaa cgtattccac aggatggaag aattagtttg cgtatcgggc gacgtaacat
     3181 agatgtccgc gtatccacac tgccgtccat ctatggtgaa cgcgccgtac tccgcctgct
     3241 ggataaaaac agcctccagc tttcattgaa caacctgggg atgacggcag cggataagca
     3301 ggatttagaa aatctcattc agcttccgca cggtattatc ctggtgacag ggccgacagg
     3361 ctccggtaaa agcaccacgc tctacgccat cctttcggcg ctgaatactc ccggccgcaa
     3421 tattctgacg gtagaagatc ccgtggaata tgagctggaa ggcattgggc aaacgcaggt
     3481 gaatacccgt gtggatatgt ctttcgctcg cggcctgcgc gccatacttc gccaggaccc
     3541 ggatgtcgtc atggtggggg aaattcgtga tacagaaacc gcgcagattg cggttcaggc
     3601 ctcgctcacc ggccatctgg tactctcaac actccacact aacagtgcat caggcgcagt
     3661 gacccggctc cgcgacatgg gcgtcgaatc attcctgctt tcgtcttccc tggcagggat
     3721 tatcgcgcaa cgtctggttc gtcgcctgtg tccgcaatgc cgacaattca cgcccgtatc
     3781 accccaacaa gcgcagatgt ttaaatatca tcagctcgcg gtgacaacaa ttggcactcc
     3841 cgtaggctgc cctcattgcc atcaatccgg ctatcagggg cgcatggcga tccacgaaat
     3901 gatggtggtg acgccggaat tacgggccgc tattcatgaa aatgtggatg aacaagcact
     3961 ggagcgacta gtccggcaac aacacaaggc cttaatcaaa aatggcctgc aaaaagtgat
     4021 aagcggtgac acctcctggg atgaggttat gcgcgtcgcc agtgccacgc tggagagcga
     4081 agcatgaatt atcgctatcg cgccatgacc caggatggtc aaaaattgca agggatcatt
     4141 gatgctaacg atgaacgtca ggcacgactg cggctgcgtg aagaagggct tttcctgctg
     4201 gatattcgcc cccaaaaaag ttcgggagta aaaacacgtc gcccgaggat cagccatagt
     4261 gaactgacgc ttttcacccg gcagttggca accttaagcg cagcggcatt acccctggaa
     4321 gagagccttg ccgtaatcgg tcaacaaagc agtaataaac gactgggtga cgtgttaaat
     4381 caggtacgca gcgccatcct tgaagggcat cccctttccg atgcattaca gcattttccc
     4441 acgcttttcg attcgctcta tcgtaccctg gtaaaagcgg gcgaaaagag cgggctgctg
     4501 gccccggtgt tggaaaagct ggctgattac aatgaaaacc ggcagaaaat ccgcagcaag
     4561 ctcattcagt cactgatcta cccctgtatg ctcactacgg tggcgattgg ggtcgtgatt
     4621 attctcctca ctgctgtcgt gcccaaaatt accgaacagt tcgtgcatat gaagcagcaa
     4681 ctgccgctga gtacacgcat tcttttaggt ctgagcgaca cgttgcaacg taccggcccg
     4741 acattattag cgacagtgtt tattgtcgct gtaggtttct ggctctggtt aaaacgcggc
     4801 aataaccgcc accgttttca tgccatgttg ctgcgcgttg cgctcatcgg cccgctgatt
     4861 tgcgccatta acagcgcacg ctatctccgc actttaagta ttttgcaatc cagcggcgtc
     4921 cctctgctgg atgggatgaa tttgtccacc gaaagcctca acaacctcga aattcgccag
     4981 cgtctggcaa atgcggcaga gaacgttcgc cagggtaaca gcattcatct ttcgctggaa
     5041 caaaccgcaa ttttcccgcc gatgatgctc tacatggtgg cctctggcga aaaaagcggg
     5101 cagctcggca cattaatggt cagagccgca gataaccagg agacactcca acaaaatcgg
     5161 agcgccttaa tgctctccat cttcgagcca gcactcatta ttacgatggc actgatcgtc
     5221 ctgtttattg tcgtgtcggt actccaacct cttcttcaac ttaactcaat gattaattaa
     5281 ggaaagcata tgcgcgcaac ggataagcaa cgcggtttta cattactgga aattatggtg
     5341 gtgatcgtca ttatcggcgt acttgccagc ctggtggttc ctaacctaat gggcaataaa
     5401 gaaaaggcgg ataagcaaaa agccgtcagc gatattgtgg cgctggaaaa cgcccttgat
     5461 atgtacaaac tcgacaatca tcactatcca accacaaatc aggggcttga atccttagta
     5521 gaagcgccga cactgccacc gctggccgca aactataaca aggaaggtta tatcaagcgt
     5581 ctgcctgccg atccctgggg caatgattat gtcctcgtta atcctggtga acatggtgca
     5641 tacgatctgc tttcagcagg gcccgatggt gaaatgggaa ccgaggacga catcaccaac
     5701 tggggtttga gcaagaagaa aaagtaagtc agcgatgaat cagcaacgcg ggtttaccct
     5761 gctggagatg atgctggtgc tggcgctggt cgctatcacg gcaagcgtgg tgctcttcac
     5821 atatggccgg gaggatgtcg ccagcactcg tgcgcgcgaa acagcggcgc ggtttaccgc
     5881 tgcacttgaa ttagccatcg accgcgccac gctcagtggt cagcctgtcg gtatccattt
     5941 ctctgattca gcatggcgca ttatggtacc gggcaaaaca ccatcagcct ggcgctgggt
     6001 tccattacaa gaagatgccg cagacgagag ccaaaatgac tgggatgaag aactctcaat
     6061 tcatcttcag ccatttaaac ctgatgacag caaccagcca caggttgtga ttctggccga
     6121 cggacaaatc acgcccttct ctttgttgat ggctaacgcc gggaccggtg agccgctcct
     6181 gacgttagtc tgttcaggct catggcccct ggatcaaacg ctcgccagag atacccgccc
     6241 atgaacaaac aatcagggat gacactgctt gaagtcttac tggcgatgag tattttcacc
     6301 gctgttgctc tgactttaat gagcagtatg caagggcaac gaaatgccat cgagcgaatg
     6361 cgtaacgaga cgctggcatt gtggatagcg gataaccagc ttcagtcaca agattcattc
     6421 ggcgaggaaa acacgtccag ttctggcaaa gagttaataa atggcgaaga gtggaactgg
     6481 cgcagcgata tccactcaag caaagacggc acgcttctgg aacgcaccat aacggtgaca
     6541 ttacccagcg gtcagacaac ctcgcttacg cgttatcaaa gcatcgataa taaatccggg
     6601 caggcacaag atgattaatc gccagcaggg tttcacattg ctggaggtca tggcggcgct
     6661 ggcgattttc tcaatgctta gcgtgctggc gtttatgatt ttttcgcaag cttccgagtt
     6721 gcatcaacgc tcacagaaag aaatccagca gttcaatcag ctacagcgca ccatcaccat
     6781 tcttgataac gatctcctgc aactggtcgc ccggaggaat cggagtacgg acaaaatcat
     6841 ggtgttgggt gaagaagcta tttttaccac gcaaagtcgc gatccgctgg ctcctctcag
     6901 tgaagcacaa accttactca ctgttcactg gtatctgcga aatcatacgc tctaccgtgc
     6961 tgttcgtact tctgtggatg gcaggaagga tcaacccgcc caggcgatgc tggaacatgt
     7021 cgagagcttt cttctggaaa gtaacagcgg ggaaagccag gaacttcctc tctcagtcac
     7081 gttacatctg cagactcagc aatatggggg gttacagcgc cgttttgcat tacctgagca
     7141 gttagcgaga gaagagtcgc cagctcagac gcaggccggg aataataacc atgaataatg
     7201 aacaacgcgg cgtcgcgctg ctcattgtac tcatgttact ggcgctcatg gctgctctgg
     7261 cagcagacat gacgctcagt tttcacagcc agcttcagcg aacccgccag gtaaaccatc
     7321 atctgcaacg gcaatatgat attgaactgg cggagaaact tgcgcttgcc agcctcaccc
     7381 aggacgttaa agataacgac agacagacca cgttgcagca gtactgggca cagccacaac
     7441 agttgcagct ggaagatggc aatacagtga agtggcagtt acgcgatgcc cagcactgtt
     7501 ttaatctcaa tgcgttagca aaaatctctg acgacccgct ggcttcccct gatttccccg
     7561 cccaggtatt cagtgcgctg ctgattaacg ccggtatcga tcgcggaaac accgatgaga
     7621 tcgtgcaatc aatcgctgac tatattgatg tcgatgactc accacgcttt cacggcgcag
     7681 aagatagctt ttaccaaagc cagacgccgc cccggcatag tgccaatcag atgctttttc
     7741 tgactggcga attacgtcag ataaaaggca taaccgaaaa catctatcag cggcttatcc
     7801 cgtatgtctg cgttctcccg accacggaac ttagcatcaa tcttaatatg ctaacggaga
     7861 acgatattcc gctcttcaga gcgttattcc tcaataacat cacggatgct gacgctcggg
     7921 tcttattgca aaaaaggccg agggaaggct ggctaaccac ggatgcattt ctttactggg
     7981 cgcagcagga tttctccggt gtgaagccac tggttgctca ggtgaaaagg catctctttc
     8041 cctatagccg ctattttacg ctgagtacgg aaagtatcag cgacgaacaa tcccagggat
     8101 ggcaaagcca tatttttttc aaccgtaaac agcagagcgc ccaaatctat cggcgtacgc
     8161 tgcaactcta ctaatcataa ggatcgtgat gcctgaatcg ttgatggtca tacgttcttc
     8221 ctcgacgctg cgtaagcatt gggaatggat gacgttctcc gcagatagcg tatcttcggt
     8281 acatacgctc acggacgatc ttccgctgga gtcgctggcc gatcagcccg gtgccggaaa
     8341 tgttcatctt ttgatcccac cagagggcct tttatatcgt tccctcacgc tgcccaacgc
     8401 caaatacaaa ctcaccgcac aaacattaca atggctggca gaggagacgt tacccgacaa
     8461 cacccaggac tggcactgga cggttgtcga taaacaaaac gaaagtgtcg aggtgatagg
     8521 cattcagtcg gagaaactca gtcgctatct tgagcgttta catactgccg gactcaacgt
     8581 gacgcgggtt ttgccagatg gctgctatct tccctgggaa gtagatagct ggactctggt
     8641 taaccagcaa acaagctggc tcattcgcag tgccgcacat gccttcaacg aactggatga
     8701 acactggtta cagcatcttg ctgcccagtt tccgcctgag aatatgcttt gttatggtgt
     8761 agtacctcac ggcgttgcag cggccaatcc acttatccag catcctgaaa taccatcact
     8821 gagtttgtat tctgccgata ttgcattcca gcgctatgac atgctgcatg gtatttttcg
     8881 taaacagaaa actgtaagca aatcgggaaa atggctcgcc cgcctggcag taagctgtct
     8941 cgttctcgcc attctttctt ttgttggcag ccggagcatc gcgctctggc atacgcttaa
     9001 gattgaagat caacttcagc aacaacagca agaaacctgg caacgttatt tcccgcagat
     9061 caaacgcacc cacaattttc gtttttactt taagcagcaa ctcgctcagc aatatcctga
     9121 agctgtgccg ttgctctatc atttacaaac acttctgctg gaacaccctg aactgcagtt
     9181 aatggaggcg aactatagcc agaagcaaaa gtcgctgacc ttaaaaatga gtgctaagag
     9241 tgaagctaat atcgatcgtt tctgtgagtt aacacagtcc tggcttccga tggaaaaaac
     9301 agaaaaagat ccggtcagtg gtgtatggac agtaaggaac tcagggaaat gattaaatca
     9361 tggtgggcag aaaaatccac atcggaaaaa cagatcgttg cggcactggc ggttctctcg
     9421 ctcggcgttt tttgttggct tggggtgata aaaccgatag atacctacat tgcagagcat
     9481 cagtcccacg cgcaaaaaat taagaaggac atcaaatgga tgcaggatca agcgagcacc
     9541 catggtttac tcggtcatcc tgcgcttacg cagcccatca aaaatatcct tctcgaggaa
     9601 gcaaaacgtg agaatttggc tatcacgctg gaaaacggcc cggacaatac tctgacaatt
     9661 catcctgtca cagctcccct cgaaaacgtc tcccgctggc tcactacggc acaggtaaca
     9721 tacggtattg ttattgaaga ccttcagttt actcttgccg gaaacgaaga gatcaccctc
     9781 aggcatttgt ccttcaggga gcaacaataa tgacaatgct actgccgctc ttcattctgg
     9841 ttggttttat tgcaggttat tttgttaatg ccatcgccta tcacctctcg ccgttggagg
     9901 ataaaacggc gttaacgttt cgccaggtat tggttcattt caggcaaaaa aaatatgcct
     9961 ggcatgatac agtgcccctg atactttgtg ttgctgctgc tatcgcctgc gccctggcac
    10021 ctttcacgcc catcgtgact ggcgcactct ttctctattt ctgtttcgta ctcacgctca
    10081 gtgttattga ttttcgcact cagctcctgc ccgacaaact caccttaccg ctgctctggc
    10141 ttggcttggt atttaatgcg cagtatggat taattgattt acatgatgcg gtttacggcg
    10201 cggtagcggg ctatggggtg ctgtggtgtg tttactgggg cgtctggtta gtttgtcaca
    10261 aagagggatt gggctacggt gatttcaagc tactggccgc tgcaggcgca tggtgtggct
    10321 ggcaaacgtt gccaatgata ctgctgattg cctcgctggg tggcattggt tacgccatcg
    10381 tttcacaact tctgcaacgc cggactataa ccactatcgc attcggcccg tggcttgcgc
    10441 tcggcagcat gataaacctg gggtatctgg cctggatctc ttattaaccg ggagggttct
    10501 ccctcccgac acggctcaac cttcttcgcg gatctgtgct tgcagataat tttgcaggcc
    10561 catcttctga atcagatcaa gttccgtttc cagccagtcg atatggcctt cttcatcacg
    10621 caaaatttct atcatcatat cgcggctgac gtaatcatga acgctatcgg cataaccaat
    10681 tgcctcacgc aaattcttcg cgccatccag ctcaagtgcc agatcagaac gcagcatttc
    10741 ctcaacatct tcaccaatgt tcagtttgcc caggtcctgt aagtttggaa gaccttccag
    10801 aaaaagaatg cgctcaatat aacgatcggc gtgtttcatc tcatcaatgg attcatgata
    10861 ctccacatca ttgagacgtt tgagacccca gtttttaaac attcgggcat ggagaaagta
    10921 ctgattgatt gcgacaagct catttcccaa cagtttgttg agataattta taactttagt
    10981 atcacctttc attttttgac tccttcgctt ccactctttg aagagtagaa cggcttacga
    11041 gtaagtcaaa aaacacactc cgtttatgcg gactccttaa actccggcag ctgcattaat
    11101 tcatcctcca tcacttcacg cgcggcccgg acacatttac cgcactgatt gccgaccgga
    11161 ataaattttt ttaattgctg gaacgagtga ggggaaaact ggcgcacagc ctgacgaatt
    11221 tttttatcgc tgataccatt acaaagacaa acgtacatag agactcccgt atactttctt
    11281 caaaaataaa tgaaaatagt tcttatttca attacggaaa gactcttttt taagcaaaga
    11341 atagaaatat gaataaaaat aatgggctac caaaagtagc ccattgacaa aaaatgcggc
    11401 gatactggaa ggtatcgcca acacatttat tgcttagtaa acggcgcgaa gatttcgcta
    11461 aatgcgtact tcggtgcctg ttctttagtc aggccgtgga attccggaga caggttagtg
    11521 ccgcccggca ggtcgcgcgc gattgaccag ataccaacca taccgagatt acgcttctgc
    11581 gcatcctgca tgaccagacg agcatcagag agatagaaca cctcgccctg aacgtcgttc
    11641 acgccaacca tcggcgtggt acccatcata gcgtcaattt ctgcatcgct cttattggga
    11701 tggaggcctt tcaattgtga atgcaggttg gcaatcgcag acgttgcaca cttaccgtga
    11761 atgttctggc cttcggtatt tgcagactga caaatcgcgt taccgtagtc cattgtcatc
    11821 acgttcacac ccgccagctc aacacctttc gctttggcat cgctcaggac attcatccct
    11881 tccggcgtca ggccagtcgg cagaattggc aaggtgtacc agatagcaat atctttgcct
    11941 tctgacttcc atttatcctg cactttcttc acagcaaggt tacgacgttc aatagatgcc
    12001 tgatccgcaa cccaggtgcc ttcgatatcg aagtccagga ctttgaggtt caggttatca
    12061 acgatgtcat aataatgctg catcagatcg tctacgttct tacaggaagc agccagcgga
    12121 gcgttgttag caccaccgat agacagcatc acatcgccgc cagcctcacg cagagctttg
    12181 attttgctgt actgagcgta attctgcata ccgtaagcgg taccccatgt cggcagacag
    12241 gtgttcgcat ctttactcac cacaaacgcc agcgtgaagt ggttgacgtt atgattctta
    12301 gccagcgcag ccagatccgg gatcgtattc agcgtaaagt cgacatacgg tgcataaacg
    12361 tgtttcggcc acgctttctt cggcgtacct acgcgctctt tggttccggt ccagtcaaca
    12421 aaaacacgcc acgggttgct gtcagaagga gaaactttct gcactttact ctgagaaatg
    12481 tagttcacac cgttaaagcg aatcagcgta tcgctggcat aaagcgtttc tggattaaac
    12541 tgcggcgcat tattcagctc ttcgttgcta tagctctgag ccttacctaa cggcttccac
    12601 gggcggctat tgctaccggt ggcgttttgg ttcgccacca gagcagggtt gtcactttgc
    12661 gtccagaaca gcgcttcata agcctgccca tcaacaacaa cgcgatcacc tttcacgtac
    12721 acagtggatg cggaccatgc tttcgccggt tcgtatttct tccacgggtt atcgccgccc
    12781 gggacaaagc cccatgcgtc ttgatcgaca gaagttttat aatgtgcatc gttataatct
    12841 acgatgctgt ccgcgctgta cgctttgctg gcctggaaac catccgcaac aatgacgccg
    12901 ccgttatcaa tttcacaggt agtcgggtta ccgtactgac tcaattccgc agcggtagct
    12961 gtacgctcga gacgccatgg gttattggag ttttcagcgc tggtaccccg tgggcaatct
    13021 ttagacccaa cccaccaggc gttcttgtaa acattaccat tgaaaataac atggtaaatt
    13081 tcgctacctt cctggccgct ccacgcttgc aatgagtaat cgttaacgct atccgctggt
    13141 gttgatggct cgctgttatc cggagttggg gtcaccggtg tttccggagt tggatcaacc
    13201 ggagtcacag caccgccatt attatccggc ttaacggaac aggagccagg gttaccatac
    13261 tggctgattt ctgttgccgt tgccgcgcga acataacgcc atgggttact ggcatcgttt
    13321 tctttcgcat cgcctgggca atttgccgcg cctacccacc aggcgttctt ataaatgccg
    13381 ccgttataga taacgtacca tgtagaagaa ccttcctgac ctttccaggc tactacagca
    13441 tagttgtcgt ttgacttatc agctggggct ggctgaacat caggagccgg tttaacgtcc
    13501 ggtgccggtt tcacatccgg tgaaggctgt ggtgctgaag tacaggactg tggattactg
    13561 gtttctgaga tttccgttgc cgtagcggca cgaacataac gccatgggtt gctggcatca
    13621 ttgcttttcg catcacccgg acagttagaa gaggctaccc accaggcatt tttatatacc
    13681 gcaccattaa agacgacata ccaggtctga ccgccctgct gtttattcca ggcaactaca
    13741 gaagaattag acggaacagt gccctgtgct ggtgtagccg aaccgccatt agccggcgta
    13801 ttggatgcag gcgtatttga atttgaagaa gatgagctgc cgctcttttc gcaggaaagt
    13861 gtattgccaa actgactaat ttcagcagct gttgcggtac gctttaaacg ccacgggtta
    13921 gttgcatcat ttgctttcgc ttttcccggg caatttgtag aagaaaccca ccaggcattt
    13981 tcataaattt tgccatcgaa aataacctga tatttattac caccttgttg gttattccat
    14041 gcttccattg ccaatgctgg cagagcggaa cacaccagcc ccataccaat catagattta
    14101 gtaaatatat ttaatttcat tataatccct tgtg
//
LOCUS       DAPHKZ010000117        14039 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.117, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000117 DAPHKZ010000000
VERSION     DAPHKZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14039
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.117"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(85..1131)
                     /gene="aroH"
                     /locus_tag="RH288_003626"
     CDS             complement(85..1131)
                     /gene="aroH"
                     /locus_tag="RH288_003626"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HDV4032644.1"
                     /translation="MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEK
                     ILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGSQPLTYGQSITDPCLGWEDTE
                     RLVEKLASAVDTRF"
     gene            complement(1288..2121)
                     /gene="ppsR"
                     /locus_tag="RH288_003627"
     CDS             complement(1288..2121)
                     /gene="ppsR"
                     /locus_tag="RH288_003627"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HDV4032645.1"
                     /translation="MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRM
                     Y"
     gene            2454..4832
                     /gene="ppsA"
                     /locus_tag="RH288_003628"
     CDS             2454..4832
                     /gene="ppsA"
                     /locus_tag="RH288_003628"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HDV4032646.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQP
                     ELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVL
                     VTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENV
                     TVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(4889..6535)
                     /gene="fadK"
                     /locus_tag="RH288_003629"
     CDS             complement(4889..6535)
                     /gene="fadK"
                     /locus_tag="RH288_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="medium-chain fatty-acid--CoA ligase"
                     /protein_id="HDV4032647.1"
                     /translation="MKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVV
                     DNHGASYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVS
                     VPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKL
                     APATSSLSLSQIIADNTPLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASER
                     AYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQ
                     RCTCMLGATPFVYDLLNLLEKQPADLSALRFFLCGGTTIPKKVARECQQRGIKLLSVY
                     GSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNV
                     FMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVE
                     DILLQHPKIHDACVVAMPDERLGERSCAYVVLKAPHHSLSLEEVVAFFSRKRVAKYKY
                     PEHIVVIEKLPRTASGKIQKFLLRKDIMRRLTQDVCEEIE"
     gene            complement(6592..6885)
                     /locus_tag="RH288_003630"
     CDS             complement(6592..6885)
                     /locus_tag="RH288_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HDV4032648.1"
                     /translation="MSQNATVNVDIKLGVNKFHVDEGHPHIILAANPDINEFRKLMKA
                     CPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTILEQWKYPAGTFGIDFRYG"
     gene            complement(6882..8171)
                     /locus_tag="RH288_003631"
     CDS             complement(6882..8171)
                     /locus_tag="RH288_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDV4032649.1"
                     /translation="MSDDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKN
                     MTGGRLYAHTLEAIIPGFAVSAPVERKVTREKISFLTEESAVTLDFHREQPDVPQHAS
                     YTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
                     GVNSMLGRSLGMVPASDPHHYAVGVKEVIGLTPEQINDRFNITGEEGAAWLFAGSPSD
                     GLMGGGFLYTNKDSISLGLVCGLGDIAHAQKSVPQMLEDFKQHPAIRPLISGGKLLEY
                     SAHMVPEGGLAMVPQLVNEGVMIVGDAAGFCLNLGFTVRGMDLAIASAQAAATTVIAA
                     KERADFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNEMF
                     TIDGKPNQPVRKMIMGHAKKIGLINLLKDGIKGATAL"
     gene            complement(8227..9165)
                     /locus_tag="RH288_003632"
     CDS             complement(8227..9165)
                     /locus_tag="RH288_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HDV4032650.1"
                     /translation="MSQLNSVWVFSDNPERYAELFGGAQQWGQQVYAIVQNTDQAQAV
                     MPYGPKCLYVLAQNDALQRTENYAESIAALLKDKHPAMLLLAATKRGKALAARLSVQL
                     NAALVNDATAVDIVDGHICAEHRMYGGLAFAQEKINSPLAIITLAPGVQEPCTSDTSH
                     QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAA
                     VLNAEVGCSRPIAEGENWMERERYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVI
                     VAINKDKNAPIFNYADYGLVGDIYKVVPALISQLSR"
     gene            complement(9185..9949)
                     /locus_tag="RH288_003633"
     CDS             complement(9185..9949)
                     /locus_tag="RH288_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein"
                     /protein_id="HDV4032651.1"
                     /translation="MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAA
                     SQLATDDDEIAALTVGGSLLQNSKVRKDVLSRGPHSLYLVQDAQLEHALPLDTAKALA
                     AAIEKIGFDLLIFGEGSGDLYAQQVGLLVGEILQLPVINAVSAIQRQGNTLVIERTLE
                     DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASDIDWSQSAPLAEL
                     VGIRVPPQTERKHIIIDNDSPEAIAELAEHLKKALN"
     gene            10265..11177
                     /locus_tag="RH288_003634"
                     /pseudo
     CDS             10265..11177
                     /locus_tag="RH288_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416211.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            complement(11220..12371)
                     /locus_tag="RH288_003635"
     CDS             complement(11220..12371)
                     /locus_tag="RH288_003635"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDV4032652.1"
                     /translation="MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMR
                     ALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSA
                     EQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
                     EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEV
                     EESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGH
                     NQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAI
                     QIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK"
     gene            complement(12385..13980)
                     /locus_tag="RH288_003636"
     CDS             complement(12385..13980)
                     /locus_tag="RH288_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDV4032653.1"
                     /translation="MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEAT
                     TLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRI
                     SELAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
                     DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNN
                     GGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQTQLYGGAPVNRFISGDFTLD
                     DSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVET
                     GPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKF
                     NGKIMGTGGFIDISATSKKIIFCGTLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEI
                     TFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPE
                     LKLMDERLFIDAAMGFVLPEAAH"
BASE COUNT         3406 a         3563 c         3538 g         3532 t
ORIGIN      
        1 gtggctgacc agagcaagca gtaatttgtt gagaagacaa caagttgcgc agaaatgccc
       61 attccgtcag gaatgggcac gcattcagaa gcgggtatct accgcagagg cgagtttttc
      121 gaccaggcgt tcggtatcct cccagcccag acacgggtcg gtaatggatt gaccgtaagt
      181 gagcggctga ctgccgacga ttttttgcgt tccttcgcgc aggaaacttt ccgccataat
      241 tccagcaatc gccgtagagc cattgcggat ttgctgacaa atatcctcac aaacttctaa
      301 ctggcgacgg tgctgcttct ggcagttacc gtggctgaaa tccaccacca gatgttcagg
      361 taaatcaaac tcgtgcagcg tatcgcaggc tgcggcgata tcatcggcat gataattcgg
      421 ttttttgccg ccacgcataa taatgtggcc atacgggttg ccgctggtct gatagatggt
      481 catctgacca tttttgtctg gcgagaggaa catatggctg gcgcgggctg cgcggatagc
      541 atccacagca atccgcgtat tgccatcggt accattttta aaacctaccg gacaggagag
      601 tgccgaagcc atttcgcggt ggatctgact ttcggtagta cgtgcgccaa tcgcgcccca
      661 actgattaaa tcagcaataa actgaccggt caccatatcg aggaactcag tcgcggttgg
      721 gacgcccagc tcatttacct gtaaaagtaa tttgcgcgcc agctccagac cgtgatttac
      781 ccgatagctg ccgtttaaat ctggatcgga gattagtcct ttccagccga caacagttcg
      841 tggtttttca aaataggtgc gcattacgat ttccagccgt gactggtact ggttgcgcag
      901 cgactgcaga cgggtggcgt actccattgc agcggtgaga tcgtggatcg agcaggggcc
      961 aataatgacc aacagtcgct tatcttcacc attgagtatt ttttcaattc tgcggcggga
     1021 gtcggtgaca tgggtggcga cgccaggcgt tacgggatac cgtagcgcga gttcggcggg
     1081 cgttaccagg ctctcaatac gcgcagtacg gagttcgtca gttctgttca ttacaagtct
     1141 cagaaatttg ttgcttctac ggcaggactg ccgggaagtg atgcgcatca cgataaacca
     1201 atcgctgctg atttcaagtg cgaggtgtgt cacacctcgc cgggtggtta gcatgataac
     1261 aaaaaaataa gctaatgcac tagttctcta gtacattcgg cgactaaggc ccatgatatc
     1321 gaggatcttg gtggcaatct cttctaccga ataattggta ctgttaatcc acgggatctg
     1381 atttttacgg tacaaggctt ccacttccgc gacttccatc ctgcactgac gaagcgaggc
     1441 atagcgactg ttctcccgac gttcctcgcg aatcgccgcc agacgttccg ggtcgatagt
     1501 caggccgaac aatttatgct gaagcggttt gagcgacgcg ggtagcacca gattatccat
     1561 atcgtcggca ataaaggggt agtttgccgc gcggatacca aattgcattg ccagatacag
     1621 actggtcggg gttttaccac agcgagaaac accgagcagg atcacctgag cctgatccag
     1681 attgcgcaac gaaatgccgt catcgtgggc gagggtgtaa tcaatcgccg caatgcgcgc
     1741 atcatattta ttgagattat tagggttaag gccatgggta cgatgagcaa tcggcgttgg
     1801 atccagtttc atctcttgtt gtagcggggc aaccagcgcc tgaacgatat cctggcaaaa
     1861 gccttcactt tgcaagatga tggcgcgaat ctccggcaac acgatggagt agaagaccag
     1921 cgggcgcacg cctgtctggt gataaattgc gtcaatctga tccttcactg cccgtgcacg
     1981 gctctcattt tcgacaaacg gcagcgtgat gctgctgata gtgacgggaa attgtgacat
     2041 tactgcgtgt cctaatacct ccgcagttat tgccgtacca tcagaaatat aaaaaacgtg
     2101 gcgatcaaca gcattatcca ttttgttctt cccgtgatgc agacataatt ctatgaaagc
     2161 ataaattaaa aacgcacaga agcgtagaac gttatgtctg gtttataaaa tgaaccttca
     2221 attttatttt ttatgaaaac agtatttcat ttttatggtt tcgtttatac cgatggttta
     2281 tgtggaaatt gtcgaagaga gcagatttgc gcaacgctgg gatcagtctt aaaaaataaa
     2341 aaaatatatt tgcttgaacg attcaccgtt tttttcatcc ggttaaatat gcaaagataa
     2401 atgcgcagaa atgtgtttct caaaccgttc atttatcaca aaaggattgt tcgatgtcca
     2461 acaatggctc gtcaccgctg gtgctttggt ataaccaact cggcatgaat gatgtagaca
     2521 gggttggggg caaaaatgcc tccctgggtg aaatgattac taacctttcc ggaatgggtg
     2581 tttccgttcc gaatggtttc gccacaaccg ccgacgcgtt taaccagttt ctggaccaaa
     2641 gcggcgtaaa ccagcgcatt tatgaactgc tggataaaac ggatattgac gatgttaccc
     2701 agcttgcgaa agcgggcgcg caaatccgcc agtggattat cgacactccc ttccagcctg
     2761 agctggaaaa cgccatccgc gaagcctatg ctcagctttc cgccgatgac gaaaacgcct
     2821 cttttgcggt gcgctcctcc gccaccgcag aagatatgcc ggacgcttcc tttgccggtc
     2881 agcaggaaac cttcctcaac gttcagggtt ttgacgccgt tctcgtggca gtgaagcatg
     2941 tatttgcttc tctgtttaac gatcgcgcca tctcttatcg tgtgcaccag ggttacgatc
     3001 accgtggcgt ggcgctctct gccggtgttc agcggatggt gcgctctgac ctcgcatcat
     3061 ctggcgtgat gttctccatt gataccgaat ccggctttga ccaggtggtg tttatcactt
     3121 ccgcatgggg ccttggtgag atggtcgtgc agggtgcggt taacccggat gagttttacg
     3181 tgcataaacc gacactggcg gcgaatcgcc cggctatcgt gcgccgcacc atggggtcga
     3241 aaaaaatccg catggtttac gcgccgaccc aggagcacgg caagcaggtt aaaatcgaag
     3301 acgtaccgca ggaacagcgt gacatcttct cgctgaccaa cgaagaagtg caggaactgg
     3361 caaaacaggc cgtacaaatt gagaaacact acggtcgccc gatggatatt gagtgggcga
     3421 aagatggcca caccggtaaa ctgttcattg tgcaggcgcg tccggaaacc gtgcgctcac
     3481 gcggtcaggt catggagcgt tatacgctgc attcacaggg taagattatc gccgaaggcc
     3541 gtgctatcgg tcatcgcatc ggtgcgggtc cggtgaaagt catccatgac atcagcgaaa
     3601 tgaaccgcat cgaacctggc gacgtgctgg ttactgacat gaccgacccg gactgggaac
     3661 cgatcatgaa gaaagcatct gccatcgtca ccaaccgtgg cggtcgtacc tgtcacgcgg
     3721 cgatcatcgc tcgtgaactg ggcattccgg cggtagtggg ctgtggagat gcaacagaac
     3781 ggatgaaaga cggtgagaac gtcactgttt cttgtgccga aggtgatacc ggttacgtct
     3841 atgcggagtt gctggaattt agcgtgaaaa gctccagcgt agaaacgatg ccggatctgc
     3901 cgttgaaagt gatgatgaac gtcggtaacc cggaccgtgc tttcgacttc gcctgcctac
     3961 cgaacgaagg cgtgggcctt gcgcgtctgg aatttatcat caaccgtatg attggcgtcc
     4021 acccacgcgc actgcttgag tttgacgatc aggaaccgca gttgcaaaac gaaatccgcg
     4081 agatgatgaa aggttttgat tctccgcgtg aattttacgt tggtcgtctg actgaaggga
     4141 tcgcgacgct gggtgccgcg ttttatccga agcgcgtcat tgtccgtctc tctgatttta
     4201 aatcgaacga atatgccaac ctggtcggtg gtgagcgtta cgagccagat gaagagaacc
     4261 cgatgctcgg cttccgtggc gcgggccgct atgtttccga cagcttccgc gactgtttcg
     4321 cgctggagtg tgaagcagtg aaacgtgtgc gcaacgacat gggactgacc aacgttgaga
     4381 tcatgatccc gttcgtgcgt accgtagatc aggcgaaagc ggtggttgaa gaactggcgc
     4441 gtcaggggct gaaacgtggc gagaacgggc tgaaaatcat catgatgtgt gaaatcccgt
     4501 ccaacgcctt gctggcagag cagttcctcg aatatttcga cggcttctca attggctcaa
     4561 acgatatgac gcagctggcg ctcggtctgg accgcgactc cggcgtggtg tctgaactgt
     4621 tcgatgagcg caacgatgcg gtgaaagcac tgctgtcgat ggcgattcgt gccgcgaaga
     4681 aacagggcaa atatgtcggg atttgcggtc agggtccgtc cgaccacgaa gactttgccg
     4741 catggttgat ggaagagggg atcgatagcc tgtctctgaa cccggacacc gtggtgcaaa
     4801 cctggttaag cctggctgaa ctgaagaaat aaaataaatc cccggcggcg ttcagtcgcc
     4861 ggggttatgt gatccccgaa gatgatactt attcaatctc ttcacagaca tcctgcgtta
     4921 atcgccgcat aatatctttt cttaacaaaa acttttgtat tttacctgag gcagtgcgcg
     4981 gtagtttttc gattaccacg atatgttcag gatatttata ttttgcgacc cgtttacggc
     5041 taaaaaaagc caccacctct tccagcgata atgaatgatg cggcgctttc agcacgacat
     5101 aagcgcatga tcgttcacct aaacgttcat cgggcattgc aaccacacag gcatcgtgaa
     5161 ttttaggatg ctgcaataaa atatcttcca cttcacggct gctaatattt tcgccgccgc
     5221 ggacaataat atcttttttg cgtccggtaa tttttatata gccagcctca tccatacggc
     5281 agagatcgcc gctgtaatac cagccttctt catccagcgc acgggcggtt aattcaggtt
     5341 catcaaaata tcccataaac acattggggc cacgcgaggc ttcttcacct tcgcaacctg
     5401 gcggtaaggt cttgcgtgcg tcatcgacca ctttaatctc tacacctgcg gcagcgtaac
     5461 catcggtgtg cataaagcgc gacaaaggat catcgagatt caccaccgca tgcggcgaac
     5521 tttctgtgga accataaaca cttaataatt taatgccgcg ctgctggcat tcacgtgcca
     5581 cttttttggg gattgtggta ccgccgcaaa gaaagaagcg cagcgctgaa aggtctgcgg
     5641 gttgtttctc tagtaaattc aaaagatcat agacaaacgg cgttgcgccg agcatacagg
     5701 tgcaacgctg ctgctcaagc agcgcgagac acgcatcagg agtgaaaata tctaacaaca
     5761 cgctgcgagc gccaatcaaa aatggtgctg ttacgccatg cagaaagccc gttgcgtggc
     5821 cgagtggcgc aggcatcata aagacatcct gccaggtcag attcagccgc gcgcaataag
     5881 cccgctcact ggcgagaata ttgttatgcg ttagcatcac gccctttggc agaccctcgg
     5941 ttccggaggt aaacagcacc gcagctaatt catcgccgtg ggtcgttatc gccgtggtca
     6001 gtggggtatt gtcggcgata atctgactta atgagaggga agaggtggcg ggagccagtt
     6061 tgtccacgcc gacaatttgt tgtagttgtg gaagctgatt ttgcagcggc aggattaaat
     6121 ctaccggacg cgtttgttta aacaacgtcg gtgcaaagaa catttttgcc tgacacttat
     6181 taagcaccca caccagttct gcttcccgcc aggaaggcaa cagcggtacg gaaaccgcac
     6241 cgattttcag gcaggcaaga tagataacgg taaattcaca ccagcctggc agttgaaatg
     6301 cgatgcgatc gcctgattca atacccttcg ctaacatcca gtttgccaga cagctcgcgg
     6361 cgtgatcgag tgcgctatag gtgtacgatg ctccatgatt atcgaccacg gcaattttgt
     6421 ctggcatcgc acgagcggtc tgctgccagt aatcggccag cgaagcatcg ccccatagcc
     6481 cttgctgacg atacgccgca cgacgttgtt cgttaaacgt taatgtcact ttcattttgg
     6541 actctcgaaa cagaacatca ggcccgatgt gcgggcctgt gggatgcgtg attagccgta
     6601 acggaaatca ataccgaagg tacctgcggg atatttccac tgttcgagaa tagtgttacc
     6661 gcacaacacc cgacaggtgc cgcactccag acaaccggca gaatcaaaat gaatgttgcc
     6721 ggcgtcatcc tgcttataaa gtccggcagg gcaggctttc attaatttac ggaattcatt
     6781 gatatcggga tttgccgcca aaatgatatg cgggtggccc tcatcaacat ggaatttatt
     6841 gacgcctaat ttgatgtcga cgttaaccgt agcgttctgg ctcatagcgc ggttgctccc
     6901 ttaatgccat ctttcagcaa gttgatcagc ccaattttct tcgcatgtcc catgatcatt
     6961 tttcgtaccg gctggtttgg tttgccgtcg atggtgaaca tctcgttcat gatgtcggct
     7021 accattcgtg ggtattggct aaacaggcgc gggttttcca tcagcgccgg gatcttgcga
     7081 aaatgctgca tatcacgcat gacgcagctt tgttccagct cacgtttgta ttgcgccaga
     7141 ctgctggcgg agaaatccgc gcgttctttg gcggcgatca ccgttgtggc ggcagcctga
     7201 gccgatgcaa tggctaaatc catgccgcgg accgtaaaac ccaaattcag gcagaagcct
     7261 gcggcgtcac caacgatcat cacgccctcg ttaaccagtt gcggcaccat tgccagaccg
     7321 ccttccggca ccatatgcgc ggaatattca agcagtttgc cgccgctaat cagcgggcga
     7381 atggcggggt gttgtttaaa atcttccagc atttgcggca cgcttttttg cgcatgggcg
     7441 atatcaccca atccacaaac cagccccaag gatatggaat ccttgttggt atagagaaat
     7501 cccccgccca tcaggccgtc agaaggggaa ccggcaaaca gccaggcggc accttcctcg
     7561 cccgtaatat taaagcgatc gttgatctgt tctggtgtga ggccaataac ctctttaaca
     7621 ccaacagcgt aatgatgcgg atcggaagcg ggaaccattc ccagcgagcg gccaagcatc
     7681 gagttaacgc catcagccag aatcaccaca ttcgcttcga gaatatcatc cccagcctgc
     7741 acgccagtga ccttgtttcc ttcacgaacc agcgcgtcga cgcgaacgcc tgggataaac
     7801 tgcgcgcccg cctgctcggc ttgttccatc aaccacgggt ccagacgatt acgcaatacg
     7861 gtataagatg cgtgttgcgg aacatctggc tgctcgcggt gaaaatcgag ggtaacggcg
     7921 ctttcttcgg ttaagaagga gattttctcg cgtgtgacct tgcgttctac cggcgctgat
     7981 actgcaaagc ctggaatgat tgcttcaagt gtgtgggcat aaagacgccc gccggtcatg
     8041 tttttacatc cggcactgtc gccgcgttct atcaccagga catccagccc ggctcgtgcc
     8101 atgaccagtg cggcaacgct accagcaacg cccgcaccga ccacaatggc atcaaatttg
     8161 tcatccgaca tgcgttatgc tcccttcccg ctgcgtttac agcgggagat gtggttgaaa
     8221 ggggaattag cggctcaact ggctaatcag ggcagggacg actttgtaga tatcgcccac
     8281 cagaccgtag tcggcatagt tgaagattgg cgcattttta tctttattga tggcgacaat
     8341 cacttttgcg ccgttgccgc caaccatatg ctggatctgc ccggagatcc ccagcgtcag
     8401 gtagagatcg gatttcagca acacgccgga gacaccgata taacgttcac gctccatcca
     8461 gttctcgcct tcggcaattg gacgtgaaca gccgacttca gcattcagca ccgccgccag
     8521 ttcgtggacc atttttaggt catcctgcgc cgccagtcca cgaccgacgc caaccacacg
     8581 ttttgctttg ctcaggtcca cgctgcttgc ggctttcgca cggcgttcgc gacagagaat
     8641 ttcatgacgc ggagcaacat aaggtaccgt ttctgtcggg cactgatgag aggtatcact
     8701 ggtgcacggt tcctgaacac cgggtgcaag ggtaatgatc gccagcgggc tgttgatctt
     8761 ttcctgagcg aacgctaacc cgccatacat ccggtgttcg gcgcaaatgt gaccatcgac
     8821 aatatccacc gccgtggcat cgttcaccag cgccgcattc agttgcacac ttaaccgtgc
     8881 tgccagcgct ttaccacgtt tcgtcgcggc caacagcaac atagcggggt gtttatcttt
     8941 cagcagggca gcaatgcttt cggcgtaatt ttcagtgcgt tgcagcgcgt cgttttgcgc
     9001 aagaacataa agacattttg gaccataagg cataactgcc tgcgcctggt cggtattttg
     9061 tacaatggca tacacctgtt ggccccattg ctgagcgccg ccaaacagtt cagcataacg
     9121 ttcaggatta tcgctaaaga cccagacgct gtttaattga ctcatcgttt cttctccgta
     9181 ggcttcagtt cagggctttc ttcagatgtt ccgccagctc ggcaatggcc tccggcgaat
     9241 cgttatcgat aatgatgtgc ttacgttctg tttgcggcgg tacgcgaatg ccgaccagtt
     9301 cagcaagtgg cgcgctctgg ctccagtcaa tatcacttgc ctgccactga tttaccggtt
     9361 ttttacccgc gccgagaatg gctttcatcg aaggaatgcg tggcacgtta atatcggagg
     9421 tgacgcagag cacggctgga acagagagtt caataacttc aacatcatct tcaagcgtgc
     9481 gttcaatcac cagtgtattg ccctgacgct gaatagcact cactgcatta atcaccggaa
     9541 gttgcagaat ttctccgacc agcaagccaa cctgctgggc ataaaggtcg ccggaacctt
     9601 caccaaagat cagtaaatcg aagccgatct tttcaattgc tgccgccagc gcttttgcgg
     9661 tatcgagagg cagtgcatgt tcaagttgcg catcctgcac caaatacagg ctgtgcggcc
     9721 cgcgggatag cacgtctttg cgcactttcg agttctgcaa caatgagccg ccaacggtca
     9781 gcgcggctat ctcatcgtca tctgttgcga gctggcttgc agcttcaatg gcattgagat
     9841 cgaactggct gattttggcg tcggcattgt cgaaattcag ggtgtattct ggagtgacaa
     9901 caatgtcctg ttcttcaggc accagcttaa agcaggttat tattttcatg atttctcctg
     9961 tgagtcgcat acggaaccat ctccgatgga aggtaaaaat ggcctgaaaa tagtgtgcga
    10021 tagcggtgcg gggttttcga cggagcaagc tgttttcctt gccaacaatc ttgcaaaaaa
    10081 aatgcgatcg ctaaaacaaa agtgcaattt gcggcaatat agttattcca tgaccgtaca
    10141 atcttgcatt cagtgtaaat aatcttgttt agctctcgct aaacgcggtt gtataaccgc
    10201 aatacacgcc gtattttatc cggcatatat tgtttttgct tgctcatgga atagggaggt
    10261 tgtcatgtat caacgctgtt ttgataacgc cagtgaaacg ctgtttgtcg ccggtaaaac
    10321 gccacggctt tcacgttttg catttagcga tgatccaaaa tgggagtccg gacatcacgt
    10381 tcatgacaat gaaaccgagt tgatttacgt caagaaaggg gttgcaaggt ttaccatcga
    10441 ttcttcgtta tatgtcgcac atgcggatga cattgtggtg atagaacgcg gcaggctgca
    10501 tgcggtggcc tctgacgtta acgatccggc aacgacgtgt acctgtgcgc tgtacggctt
    10561 tcagtttcag ggggctgagg aaaatcagct actgcaaccg cattcttgtc cggtaattgc
    10621 cgcggggcag ggaaaagaag tcataaaaac cttatttaat gagctaagtg tgattttgcc
    10681 gcaaagtaaa aatagccaaa catcttcgtt atgggatgca tttgcctata cgttagccat
    10741 tctttactac gaaaatttta aaaatgctta tcgttcggag caggggtata ttaaaaaaga
    10801 tgttctgata aaagatattc ttttctatct gaataataat tcatcgcgaa aaaatcactt
    10861 tagaacagtt atcgaaaaaa tttcgtgcca gcgtcagtta tatttgccat gaatttacca
    10921 aagagtatcg tatttcccct attaactatg ttattcaacg gcgtatgacg gaagcaaaat
    10981 ggtcactcac taatactgaa ttatcacagg cagagatctc ctggcgtgtg ggttatgaaa
    11041 atgtcgatca ctttgccaaa ctgtttttgc gccatgtcgg ttgttcgccc agcgattacc
    11101 gtagacaatt taaaaactgt tttgcggaac aagaaatcct atctgaattt cctcaaccgg
    11161 taagtcttgt tggataaatc tggcggcgca gtttgttaag aagctgcgcc gcctgcagat
    11221 tatttgttct gatagtcttt caggatctgc cgacctgcta cgtaaatcat aatttcgtct
    11281 gtaccgccgc cgatacgttc acaacggaca tcacgccaga agcgggagac gcgcgcctca
    11341 tcggtatagc ccagaccgcc catgatttga atcgcatcat caatgacttc cattgcggta
    11401 cgtgcacagt acagttttgc cagcgccgcg ctggtgcgca gtgactgatg ctgatcggct
    11461 tgccatgcca ctttcagcac catgttgcgc atgttgtcga tcttaatcgc catcagcgcc
    11521 agtttttcct ggatcatctg gttatgacca atgggcttac caaaagcgat acgttggttg
    11581 gcatagcggg cggcatcttc aaaggcgcat tcggcaaagc cggtgctgcg cgcggcgttg
    11641 atcaggcgct ccatctcaaa gttgtacatc acattgagga aacccattcc ttcttcgccc
    11701 accatgtcgc tctcttcaac ctccacgttg tcgagataga cttcgcaggt gctgagcata
    11761 tgccagccga ttttatgcag cgggttaatc ttaatgccgg gcttactgga gtcgacccac
    11821 cacagggtga aggctttttt gggatctttc ggttgcggat cgcgcgccag caccagcata
    11881 tacgggtact ctttcgcacc ggtaataaag gttttttgtc cgttgatgta gaccttgccg
    11941 tttttacgcg tgtaagtggt agtggcactg ttgttatctg agccagcacc tggttccgtc
    12001 aacgccaggg cataggcggg atcacccgtt tccagggtgc tctctgccgt tttacgtagc
    12061 tgctctgcag aaccgaaacg gcgcatactg tgaatacatt gaccgttggt aattaaaaat
    12121 gccggagcac cgcattttga cacttccatc agcgccagca tttgggtgac gtaatccgca
    12181 gggataccac caaattcttc cggcacgcca agcatggaaa taccgttatc cgccagcgcc
    12241 cgcataaact cacgcggata tgtcccgttt tgatcgcagg tgcggaaata ctcttccgga
    12301 aagttagtcg taatcagttc gcgaatactg gccagcagca gttcttgttc ttcagttaaa
    12361 gaaaaatcca tcattatact cctgttaatg agcagcttca ggcaggacaa aacccatcgc
    12421 cgcatcgata aataatcttt cgtccatcag tttgagttct ggcgaaatca ctggggtgaa
    12481 atccattttg tcgagaatat ctttttgtaa atcgacgcca ggggcgattt cgattaaatg
    12541 caggccgtct tctttcagcg tgaatactgc gcgctcagtg atataacgaa catccagccc
    12601 tcgctcgaga gcgatttttc cgctgaaagt aatttccggt agttcccgaa taaatttctt
    12661 cacccgtcct tcctggacga tatttaattt gccgtcggta atttctgttt ttaaactgcc
    12721 cgcagttaat gtgccgcaga aaatgatttt cttcgaagtg gcactgatat caataaatcc
    12781 accggtgccc atgattttac cattgaattt atgcacgccg acgttaccgt gctggtcgac
    12841 ttcagcaaaa ctcaaataac aaacatccag accgccaccg tgataaaaat caaactggga
    12901 cgtcatatcc agaatggcac gggtattcac gttcgcgcca aaggcgatcc cctgtgaagt
    12961 aattccgcca atcggacctg tttctaccgt cagaataaag tcatcagcac aaccttcttc
    13021 tcgggcgacc aggccaatgc cgtcagcaat accgacgccg acattcccca ccgcgccttt
    13081 acgcatttcg aataatgcgc gccgcgcaac taatttacgt tggtttaggg gcaggctaag
    13141 tttggtactg tcatcaaggg tgaagtcacc agaaataaag cggttaaccg gtgcaccgcc
    13201 atacagttgg gtttgatccg gatcgaccac cacaatatcc accagataac ccggaatacg
    13261 gacagattta ggatgcagcg tggctttctt aaccattttc tgcacctgca tcatcacaat
    13321 accgccgtta ttgtgcaccg cctgggcaat aaccaatgcg tcgagataca tcacctcatc
    13381 ttcaaaagtg gcgtagcctt cactgtcgca ggtggtagcg cgaatgaagg caatatctgg
    13441 cgcaatcgct ttgtaataga gatattcttt gttatcaaac tcgaccagtt taatcaggtc
    13501 ttctttagtg acttcattca gtttgccgcc ttgctggcgt ggatcgacaa atgtcccgat
    13561 gccaatatca ctaataatac caggctggtg ggctgcggcg gcgcgtaagg tttgtgtaag
    13621 tacaccttgt gggtagttat aagcaataat tttattttgt tctgcgagtt cagaaatacg
    13681 cggcgattgt ccccagtgac cacataatgc ccatttcacc agaccttctt gcgccagagg
    13741 actaatacca cggtcggcgc gatcgccaag ccctgttgga ctaataatcg ataaattacg
    13801 tggtgtttga gtctgtttat atttatcagc aagagcagta attaacgtgg tggcttccag
    13861 aataccgccg ccagcgccta acacacaaag tgttgcttcg tcgggaatat aattcaccgc
    13921 ttcctgtgcc gacaggaccg gcactcgtcc attaatacga ggtggtttta caggtttcat
    13981 tgttaattcc tgattcagat gtgattttcc ctacgccaaa tggagaatta gcgcacaga
//
LOCUS       DAPHKZ010000118        13791 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.118, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000118 DAPHKZ010000000
VERSION     DAPHKZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13791
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.118"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..982
                     /gene="espX5"
                     /locus_tag="RH288_003637"
                     /pseudo
     CDS             1..982
                     /gene="espX5"
                     /locus_tag="RH288_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418490.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="T3SS effector pentapeptide repeat protein EspX5"
     gene            complement(1136..2785)
                     /locus_tag="RH288_003638"
     CDS             complement(1136..2785)
                     /locus_tag="RH288_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HDV4032654.1"
                     /translation="MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVVVTVVGIGF
                     LIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDIILIYAALMLVRFGW
                     LWTMKKFSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFP
                     ARYELVFLAAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSVQEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ"
     gene            complement(2936..4285)
                     /gene="ghxP"
                     /locus_tag="RH288_003639"
                     /gene_synonym="yjcD"
     CDS             complement(2936..4285)
                     /gene="ghxP"
                     /locus_tag="RH288_003639"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HDV4032655.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGL
                     IFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI"
     gene            complement(4831..5295)
                     /gene="soxR"
                     /locus_tag="RH288_003640"
     CDS             complement(4831..5295)
                     /gene="soxR"
                     /locus_tag="RH288_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HDV4032656.1"
                     /translation="MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVLPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN"
     gene            5381..5704
                     /gene="soxS"
                     /locus_tag="RH288_003641"
     CDS             5381..5704
                     /gene="soxS"
                     /locus_tag="RH288_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HDV4032657.1"
                     /translation="MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSD
                     YRHRL"
     gene            complement(5707..7293)
                     /gene="pdeC"
                     /locus_tag="RH288_003642"
     CDS             complement(5707..7293)
                     /gene="pdeC"
                     /locus_tag="RH288_003642"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdeC"
                     /protein_id="HDV4032658.1"
                     /translation="MSHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRT
                     FAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDN
                     HFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
                     FWSEVMSDDPTLQWGVYDTVTKTFFSLSKEASAATFSPLIHLKDLTVQRNGYLYATVY
                     STKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQ
                     RALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQIMNPAEFIPLAEKEGMIEQI
                     TDYVIDNVFRDLGDYLATHADRYVSINLSASDFHTSRLIARINQKTEQYAVRPQQIKF
                     EVTEHAFLDVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVE
                     TLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEEQVNWLRKRGVRYCQGWFFAKAMP
                     PQVFMQWMEQLPARELTRGQ"
     gene            7723..8004
                     /locus_tag="RH288_003643"
     CDS             7723..8004
                     /locus_tag="RH288_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HDV4032659.1"
                     /translation="MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRSDYVGLAVISS
                     GLGVVSACWFAMGLLGITMADITAIWHNIESVMIEEMNQTPPQWPMILT"
     gene            complement(8103..8639)
                     /gene="ssb1"
                     /locus_tag="RH288_003644"
     CDS             complement(8103..8639)
                     /gene="ssb1"
                     /locus_tag="RH288_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HDV4032660.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     ATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEV
                     VVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
                     PAAPSNEPPMDFDDDIPF"
     gene            8893..11715
                     /gene="uvrA"
                     /locus_tag="RH288_003645"
     CDS             8893..11715
                     /gene="uvrA"
                     /locus_tag="RH288_003645"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDV4032661.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDIDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLA
                     ESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEA
                     PWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAG
                     QRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVSGTPETVAECEASHTARFLKPML"
     gene            complement(11750..12106)
                     /locus_tag="RH288_003646"
     CDS             complement(11750..12106)
                     /locus_tag="RH288_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDV4032662.1"
                     /translation="MTISELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVEN
                     RPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQ
                     AVNLLPEEKRKLLVQL"
     gene            complement(12110..12526)
                     /locus_tag="RH288_003647"
     CDS             complement(12110..12526)
                     /locus_tag="RH288_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HDV4032663.1"
                     /translation="MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQH
                     TSASLTLNENCDPTVRHDMERFFLRTVPDNGNYEHDYEGADDMPSHIKSSMLGTSLVL
                     PVHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE"
     gene            complement(12637..13350)
                     /gene="aphA"
                     /locus_tag="RH288_003648"
     CDS             complement(12637..13350)
                     /gene="aphA"
                     /locus_tag="RH288_003648"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HDV4032664.1"
                     /translation="MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQA
                     PIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
                     NMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTY
                     KPLPQAGAFGEEVIVNSEY"
BASE COUNT         3639 a         3537 c         3324 g         3291 t
ORIGIN      
        1 cgatagaatt acgagaagag tttaccttaa taaagataag gaagtgtcaa ttaaggtggt
       61 atattttata aataatgtca ccgtccataa taatactatc gaaatcccac agacagtaaa
      121 tggtggttac gatttttcac accttagcct gaaaggtatc gtgattaaag attaagattt
      181 atccaattcg aattttgcag gttgcagact acaaaacgct atttttcagg actgtaatat
      241 gtataaaacg aattttaatt tcgccataat ggaaaaaata ctttttgata attgtattct
      301 cgatgactca aatttcgctc agataaaaat gactgacgga actctaaatt catgttccgc
      361 tatgcatgtt caattctaca atgcaacaat gaatagagcc aatattaaaa ataccttcct
      421 tgattattca aatttttata tggcatacat ggctgaggta aatctttata aagtaatagc
      481 gccatatatt aatttattta gagccgacct tagcttctct aaacttgatt taattaactt
      541 tgaacatgct gatctgtctc gtgtcaacct gaataaagca accctccaga atataaactt
      601 aattgatagc aaactctttt ttacgcggtt aacaaatacg ttcctcgaaa tggttatatg
      661 taccggctct aatatggcta atgttaattt taataatgcc aatttaagca attgccattt
      721 caactgttct gttttaacaa aagcctggat gtttaatatc cgtctctatc gtgttaattt
      781 cgatgaggct agcgtccagg gaatgggtat taccattctc cgtggtgagg aaaatatctc
      841 cattaatagt gatatcctgg taacactaca gaaattcttt gaagaagatt gtgccactca
      901 tactggcatg tcacaaactg aggataatct tcatgcagtc gctatgaaga ttactgcaga
      961 tattatgcaa gatgcagatt gaggttaagt cgaagaacag ccaatgaatt gactttaaaa
     1021 gagagataac ttatttgttt tagaatcatg aatgttagcc cgagctaacc tgttaaaggt
     1081 gcaaaagatt gcaccttttt cagattacct cgggcctggt tacgtcgctt tcggcttact
     1141 gattttcctc aattagcaac gcttcaagca aatcgagatc gtgcagtaat ttttgcagcg
     1201 tttcgttgct gatctcccgt gtggcgcgca ggtggtaaag ttcagcacgt tcagaacgca
     1261 atgccgccag acggaagcga cgctcaaggt tctcttcctg cacggaactt tcaacgtcgt
     1321 tacgtccatc ggcgcgacga cgcaggttac caatgacgcg agaactgacc tccgtaagca
     1381 gctggttatc gatattctct tcggtatccg ccgccagacg ctcctccatt ttctggatcg
     1441 ccacaatcgc cacttctgcc gttgccgctc gcgcaatacg ttcctctttc aattgttgcg
     1501 aatgatccgc gacttcaatg tgttgtagca gaataggcaa catcaccacg ccgacaaaca
     1561 gcgagaagag aatgacgcca gccgccagga acaccagctc atagcgcgcc gggaagacgt
     1621 taccatccgg caagagcagc gggatagaga gcacaccggc cagagtgatc gccccacgca
     1681 ccccggcgaa agacgcgatc aggatttctc gtgtggtcca cgaaccaaac tccatcggct
     1741 tcttcttcag gaagcggttg ctgaactttt tcatcgtcca cagccagccg aaacggacca
     1801 gcatcagcgc cgcatatatc agaataatat cggtaaacag catccagatt tcgacgttag
     1861 ggtcgatttc tgctgccatc agcgacgtct ccagaatacc cggcagctgc agacctaaca
     1921 gcaggaacac catgccgtta aagacaaatt ccagcatcgc ccaggtgctg tttgcacgca
     1981 ggcgcattgc cagcggcgca cggcgcatca caccggagcg ggtgatggtc atcccggcgg
     2041 caaccgcagc gaggatgccg gaaacgccaa tatgttcggc aatcagataa gaagcgaatg
     2101 gcagcaggaa cagcaggacg atctgcgtcg cgggttcatc accgccccag cggctgagga
     2161 atcgcagcga gcgaccgtac agccagctca ccacaaaacc ggcgagaata ccgccaatgg
     2221 ctactttcat aaattcgacc gtcgcaccgc cgacggtgaa gatcatcgtc cccatcgcca
     2281 ctgctacggc aaacttcaac gacaccagac cggaggcgtc attcatcaac gcttcgccct
     2341 gcaaaatgcc catgattttt ttcgggatgc gcccttcgcc aacaatcccg gagagcgcca
     2401 cagcatcggt cggagaaagc accgccgcca gcgcaaaggc agggatcagc ggaatgcccg
     2461 gcaccaccca gtaaataagg aagccaatgc cgaccacggt gaccaccacc agcgccagcg
     2521 cgaggccgaa aatctctcga ccatgttcga gaaattcacg ggtcggcgtt ttccagccat
     2581 cagcgaacag caacggcggg ataaacaaga ctaaaaagag ttcaggatca aactccacat
     2641 gcaaaccaaa cgtcggccac gccagtagcg caccgatggc gatttgcata agcggaagcg
     2701 ggatctgaaa gggcatgaca cgagtgacca ccccggacag cgagaccacg agggtcatta
     2761 tcagtatggt gaagaagatt tccatgcgtt ccctgtttgc gatgtttttt atgatctgag
     2821 aaagacgtta tgcctgaatt ctcatttttt cagaatatcg caaaagctca cacaatgtgc
     2881 ggagaaaata aaaacgggca gccattgcca cccgttttca gaatccgatg aaagattaga
     2941 tagcccagcc acccgcatag aaggtcacca gcgccacggc gataacgacc gtaccgatgt
     3001 tcaacttgcg ccattcgccg gaaaccagac gaccaatcac cagagtcgcg aagccgatca
     3061 tgatgcctgt tacgatgtta caggtcagca cgatgaatac agccgtaacc agacccgcca
     3121 tcgcatcaac aaaatcagca aagtcgattt tcgccacgtt gctcagcatc agcaggccaa
     3181 cgtacatcag cgccggagcc gttgcatacc ccggaacgag gtaagagagc ggagagagga
     3241 acagaatcaa gaggaacagc acgccaacgg tgatagccgt caaaccggtt ttaccgcccg
     3301 ccgccgtacc cgccgcagac tcgatgtata ccgctgccgg agccgcaccc accaggccag
     3361 agaaaacgct gctcatggag tcagtggtca gtgctttccc accgtcgatg atctgcccat
     3421 ctttatccag caggttcgcc tggccggcga cggcacggat agttccggtg gcatcaaata
     3481 ctgccgtcat caccagcgcc agaacgcttg gcaggactac aggattcagc gcgcccataa
     3541 tgtccaggct gccaatcagt gaattgccgt tttcatcgct caatgaaggc atggcgaaaa
     3601 cgccggagaa atggacgtta ggatcgaaga tcaaaccgac aattgagata ccgataatgg
     3661 tcagcagaat gccaccaggg actttcagtt tttccaggcc gatgatcacc gccagaccta
     3721 ccagtgacat aatcaccggg aaggtcgcga aatcacccag cgcaacgggc agaccatcaa
     3781 gcgggttttt aatcaccaga ccgacaccgt tagcggcaat gagcagcagg aacagaccga
     3841 taccaatccc cgtgccgtgc gccacaccgt gaggcaagtt gcgcaaaatc cagctacgga
     3901 tacccgtggc agaaattacc gtaaacagca cacccatcag gaacacggca cccagcgcga
     3961 caggtacgct aatatgttgc cccagcacca ggctgaatgc ggtaaacgcc gtcagggaga
     4021 tggcgcaacc aatcgccaac ggcagattag cccacagacc catcacgata gaaccgagtc
     4081 cggcaaccag acaggttgca acgaaaactg ccgcaggcgg gaagcctgct ttacccaaca
     4141 tacctggaac gacgatgacc gagtagacca tcgccagaaa cgttgttaac ccggcaacca
     4201 cttcctgacg gacagtgctt ccacgttgtg aaattttaaa ccaggcgtcg agtgaaccgc
     4261 cggtacgcgc tgatggcgta gacataagaa aacatcccct gagagtttaa ttttcgtcaa
     4321 gatgcgtggc ggacaatccc ctgccagcga aacgttatct tcctgctcca ggtttgcgac
     4381 aatttgctgc gtcgcaaaaa agcaaacgtt tagctccgcg catacaaaac gggtggtaaa
     4441 aaaagcaaac gattatccgg cgatcatagc ggctttttca accgaagttt gctgcttttt
     4501 tctcttttat tgtcttgacg atgaaaaacc aggcaattga tgcgcaaacg ttatcgtcgg
     4561 tgcgcaagat tgcagcgtta tcgagccgta taccgttcag gattgcgata aaaaatcgtc
     4621 tgagatgaca aaaatattgc ggttaaaaag tatactttta cactggcgaa gaaacgtcgg
     4681 tgacatacaa ttaaagcatc aacaccaacc ggaacctcca ccacgtgctc gaatgaggtg
     4741 tgttgacgtc gggggaaacc ctcctgtgta ccagcgggat agagagaaag acaaagaccg
     4801 gaaaacaaac taaagcgccc ttgtggcgct ttagttttgt tcatcttcca gcaagcgtgc
     4861 gccggtacct tcttctccta agcggtcgcc cgggttacgc aacgggcaat cactgcgcga
     4921 aaggcagcca caaccaatac atccgtccag ttcgtcacgc agcgccacta aggtatgaat
     4981 gcgccgatcc aactcttctc gccattggga cgaaagctgt ttccactctt tcgcacttaa
     5041 cgtatgccct tcgggcaaca cgccaaacgc ttcaccaatg gtcgccagcg gaatgccaat
     5101 acgctgagca attttgataa ttgcaacata tcgcaacaca tcacgtttat atcgccgctg
     5161 attgccgctg ttacggatac tggtaatcaa ccctttactt tcatagaaat gcagcgccga
     5221 taccgccaca ccgctgcgtt tcgccacttc gccgggggtt agcagcgctt taatgcgggg
     5281 taatttcttt tccataaatc gctttacctc aagttaactt gaggaattat actccccaac
     5341 agatgaatta acgaactgaa cactgaaaag aggcagattt atgtcccatc agaaaattat
     5401 tcaggatctt atcgcatgga ttgacgagca tattgaccag ccgcttaaca ttgatgtagt
     5461 cgcaaaaaaa tcaggctatt caaagtggta cttgcaacga atgttccgca cggtgacgca
     5521 tcagacgctt ggcgattaca ttcgccaacg ccgcctgtta ctggccgccg ttgagttgcg
     5581 caccaccgag cgtccgattt ttgatatcgc aatggacctg ggttatgtct cgcagcagac
     5641 cttctcccgc gttttccgtc ggcagtttga tcgcactccc agcgattatc gccaccgcct
     5701 gtaattttat tgcccgcgcg ttaactcccg cgcgggtaat tgctccatcc attgcataaa
     5761 cacctgcggc ggcatcgcct tcgcaaagaa ccatccctgg caatagcgca cgccgcgttt
     5821 gcgcagccag ttaacctgct cctcagtttc gacgccttca gcgatcgttt ttaaccccag
     5881 gctgtgcgcc agctcgatga tgtgttccgc aatcaaatga ctggttttgt gggtggtcag
     5941 cgtttcaaca aacgatttgt cgattttcaa aatatcgaca ttcaatgatt taaggttatg
     6001 caagttagag tagccaatac caaaatcatc aattgccact tcgtaacctg cctggcggaa
     6061 agccagaata atcggcgtca ttttgtcaac atcaagaaat gcatgctcag tcacttcaaa
     6121 tttaatttgc tgcggacgca ccgcgtattg ctctgttttc tgattgattc gcgctatcaa
     6181 ccgtgacgta tgaaaatcgg aggccgacag gttaatagaa acatagcgat ctgcatgtgt
     6241 tgccaggtaa tcgcccagat cgcggaagac attatcaata acataatcag ttatctgttc
     6301 tatcatcccc tccttttctg ccagcggaat aaactctgcc ggattcatta tttgcccctg
     6361 ctcaccaggc caacgtaaca acgcttcagc gccgatacat ttttctgttt tgatatcgat
     6421 tattggctgg taataaagac aaagttgatg tttttcgagg gcgcgttgca atttacgttt
     6481 gggagataaa tagttttgtc gaatacgtag ccagagtaat agcagaacaa gactccccaa
     6541 aataccggcg ggcaacgcaa aaataagatg attataaaaa tgggttataa gacgttgata
     6601 tgaagtcgca acaatggctg caattgggcg ttttgtcgaa taaactgtcg catataaata
     6661 gccatttctt tgtacggtta aatccttcaa atgaatcagc ggagaaaacg ttgctgccga
     6721 ggcctctttg cttaacgaga aaaaggtttt cgtcaccgta tcatacacac cccattgcaa
     6781 tgtcgggtca tcagacatca cttcactcca gaagagaggg ttgataaccg ccacataatt
     6841 tccccgctgc atataggtca ttttatagcc agagaaaaaa ggcgtatcgc ggtaataata
     6901 gatagaaacg ttaggttcac gcttataatc ggccggtgca atcgtatagc cgtttacagg
     6961 cgctatcagc gatgagcata aaaaatggtt atcacgggca tagatcaatt cattaatata
     7021 aagatagcca cgaataatat tcaacattcg cttttgatgg gctggagtgc aaacttgccc
     7081 ctgatagcgt tcagctgcat cgctcactaa atctgcctgg cgaatgacca gctcggattt
     7141 atccagtgcc agttgagcaa aggttcggag ctgattattc acttctgatt ttgcccaaag
     7201 gaaggcaatc catagcgaaa gaatgatggg aaagagaact aaaaagataa tgcccggcaa
     7261 cgccagtaat tggtgtcgtg cacgatgact cattgctatc aatttcctgc ctgtttatac
     7321 ccggccattg caaggtgaaa accctgggta ccgacgtctt tagataaatc ttacggtata
     7381 aatagcactt ttgcctgatt tgaaattgat acctttctaa tcgtcacctg gatgaaaata
     7441 attcattgat attcaaaatt aatttcctac aggaatgcag aggcggcggg aagatatgcc
     7501 cttaatgcca ctgaaaaacc acataatctg tacagcaata aaagtcacgg cctaatatgg
     7561 ctaacaaaca atcaattgtg atatagttca caaaattaat gaaacaaaca gagtgtttca
     7621 tttttgtgtt ctgcaagccc cgcgatagcc agagtgtacc acgcctcccg tgaacaacgc
     7681 cgcgctgtcc agggcatcgg ctcttttcag aggaattgtt tgatggctac cctcaccact
     7741 ggcgtggttc ttcttcgctg gcaacttctt agtgccgtaa tgatgtttct ggccagcaca
     7801 ctcaacatcc gttttcgtcg gtctgattat gtcgggcttg cggtgatcag cagcggtctg
     7861 ggcgttgttt ccgcctgttg gttcgcaatg gggttgcttg gcatcacaat ggcggacatc
     7921 accgctatct ggcacaacat cgagtcggtg atgatagaag agatgaatca gacaccgcca
     7981 caatggccaa tgattttgac ctgatacgta gaagcctcca taacggaggc ttctttttta
     8041 tggctggcag atgctttaat catccacctt aaaacaatat aacctattgt tttaatgaca
     8101 aatcagaacg gaatgtcatc atcaaagtcc atcggcggct cgttagacgg cgctgccgga
     8161 gcggactgct gcgggcgaga ctgcgcgccg ccgctgaact gattgccacc ctgcggctgc
     8221 tgaggctgac cccaaccgcc ctgcggctga ccaccaccga tattgccacc tgccggagcg
     8281 ccaccaccct gacgaccacc cagcatctgc atggtgccgc caacgttcac cacgacttct
     8341 gtggtgtagc gatcctgacc ggattgatcg gtccatttac gggtacgcag ctgaccttcg
     8401 atataaacct gagaaccttt acgcagatat tcgctcgcca cttctgccag tttgccgaac
     8461 agcacaacgc ggtgccattc agtctgttct ttcatctcgc cggtcgcttt atcacgccag
     8521 gattcggaag tagccagcgt aatgttggca actgcgccac catttggcat gtagcgtact
     8581 tccgggtcct gacccagatt accaacgaga ataaccttgt ttacgcctct gctggccatg
     8641 ttcgtgtctc ctgaaaaaaa tcgttctgaa taagtgtaaa cgcgcgattg taccattacc
     8701 aatagcgctt ttactatgtt gtgacctcgg ttccgggaaa caaacctggc cagacattgt
     8761 tacacaacac tccgggtaat gcattccaat actgtatatt cattcaggcc aatttgtgtc
     8821 ataattaacc gtttgtgatc gccggtagca ccatgccacc gggcaaaaaa gcgtttaatc
     8881 cgggaaaggt gaatggataa gatcgaagtt cggggcgccc gcacccataa tctcaaaaac
     8941 atcaacctcg ttatcccccg cgacaagctc attgtcgtga ccgggctttc gggttctggc
     9001 aaatcctcgc tcgctttcga caccttatat gccgaagggc agcgccgtta cgttgaatcc
     9061 ctttccgcct acgcgcggca gtttctgtca ctgatggaaa agccggacat cgatcatatt
     9121 gaggggcttt ctcctgccat ctcaattgag cagaaatcga cgtctcataa cccgcgttct
     9181 acggtgggga caatcaccga aatccacgac tatttgcgtt tgttattcgc ccgcgttggc
     9241 gagccgcgct gtccggacca cgacgtcccg ctggcggcgc aaaccgtcag ccagatggtg
     9301 gataacgtgc tgtcgcagcc ggaaggcaag cgtctgatgc tactcgcgcc aatcattaaa
     9361 gagcgcaaag gcgaacacac caaaacgctg gagaacctgg caagccaggg ctacatccgt
     9421 gctcgtattg atggcgaagt ctgcgatctt tccgatccgc caaaactgga actgcaaaag
     9481 aaacatacca ttgaagtggt ggttgatcgc ttcaaggtgc gtgacgatct tacccaacgt
     9541 cttgccgagt catttgaaac cgcgctggag ctttccggtg gtaccgcggt agtggcggat
     9601 atggacgacc cgaaagcgga agagctgctg ttctccgcca acttcgcctg cccaatttgc
     9661 ggctacagta tgcgtgaact ggagccgcga ctgttttcgt ttaacaaccc ggcgggggcc
     9721 tgcccgacct gcgacggcct tggcgtacag caatatttcg atcctgatcg agtgatccag
     9781 aatccggaac tgtcgctggc tggtggtgcg atccgtggct gggatcgccg caacttctat
     9841 tatttccaga tgctgaaatc gctggcagat cactataagt tcgacgtcga agcgccgtgg
     9901 ggcagcctga gcgcgaacgt gcataaagtg gtgttgtacg gttctggcaa agaaaacatt
     9961 gaattcaaat acatgaacga tcgtggcgat acctccattc gtcgtcatcc gttcgaaggc
    10021 gtgctgcata atatggagcg ccgctataaa gagacggaat ccagcgcggt acgcgaagaa
    10081 ttagccaagt ttatcagtaa tcgtccgtgc gccagctgcg aagggacgcg tctgcgtcgg
    10141 gaagcgcgcc acgtgtatgt cgagaatacg ccgctgcctg ctatctccga catgagcatt
    10201 ggtcatgcga tggaattctt caacaatctc aaactcgcag gtcagcgggc gaagattgca
    10261 gaaaaaatcc ttaaagagat cggcgatcgt ctgaaattcc tcgttaacgt cggcctgaat
    10321 tacctgacgc tttcccgctc ggcagaaacg ctttctggcg gtgaagcaca gcgtatccgt
    10381 ctggcgagcc agattggtgc gggcctggtt ggcgttatgt acgtgctgga cgagccgtct
    10441 atcggcctgc accagcgtga taacgagcgc ctgttgggta cgcttatcca tctgcgcgat
    10501 ctcggtaata ccgtgattgt ggtggagcac gacgaagacg caattcgcgc cgctgaccat
    10561 gtgatcgaca ttggcccggg cgcaggtgtt cacggcggtg aagtggtcgc agaaggtccg
    10621 ctggaagcga ttatggcggt gccggagtcg ttgaccgggc agtacatgag cggcaaacgc
    10681 aagattgaag tgccgaagaa acgcgttccg gcgaatccgg aaaaagtgct gaagctgaca
    10741 ggcgcacgcg gcaacaacct gaaggacgtg acgctgacgc tgccggtggg tctgtttacc
    10801 tgcatcaccg gggtttcagg ttccggtaaa tcgacgctga ttaacgacac actgttcccg
    10861 attgcccaac gccagttgaa tggggcgacc atcgccgaac cagcaccgta tcgcgatatt
    10921 caggggctgg agcatttcga taaagtgatc gatatcgacc aaagcccaat tggtcgtact
    10981 ccacgttcta acccggcgac ctataccggc gtgtttacgc ctgtgcgcga actgtttgcg
    11041 ggcgtaccgg aatcccgtgc gcgcggctat acgccgggac gtttcagctt taacgttcgt
    11101 ggcggacgct gcgaggcctg tcagggcgat ggcgtgatca aagtggagat gcacttcctg
    11161 ccggatatct acgtgccgtg cgaccagtgc aaaggtaaac gctataaccg tgaaacgctg
    11221 gagattaagt acaaaggcaa aaccatccac gaagtgctgg atatgaccat cgaagaggcg
    11281 cgtgagttct ttgatgccgt acctgcactg gcgcgtaagc tgcaaacgtt gatggacgtt
    11341 ggcctgacgt acattcgact ggggcagtcc gcaaccaccc tttcaggcgg tgaagcccag
    11401 cgcgtgaagc tggcgcgtga actgtcaaaa cgcggcaccg ggcagacgct gtatattctc
    11461 gacgagccga ccaccggtct gcacttcgcc gatattcagc aactgctcga cgtactgcat
    11521 aaactgcgcg atcagggcaa caccattgtg gtgattgagc acaatctcga cgtgatcaaa
    11581 accgctgact ggattgtcga cctgggacca gaaggcggca gtggtggcgg cgagatcctc
    11641 gtctccggta cgccagaaac cgtcgcggag tgcgaagcat cacacacggc acgcttcctt
    11701 aagccgatgc tgtaatcgtt aaggccgctt tctgagcggc cttttccttt cagagttgca
    11761 ccagcaattt acgtttttct tccggcagta aattcaccgc ctgctgataa gacgcatcca
    11821 ccagataata gatttgcgaa tctggcagcg aaccgtcgag atacacggtg ctccagtgcg
    11881 ctttattcag atggcggctt ggacgcacat cgctgtgctg ctgacgtagc agctccgcca
    11941 gctccgggct ggttttcagc gaaacagctg ggcgattttc tacttctttc accatcgcaa
    12001 acagtacatc ttccactttg atctgcgtcg ctttccagtc attatgcacg ctctgttctg
    12061 cgcctggttt tgccatgcaa tattgtagca actccgaaat ggtcattttt tactcccctt
    12121 gtagtgtcgc gatgatgcga cgcgatccgc cgtggatgcg atgttccccc agccaaatgc
    12181 cttgccaggt gccggtctga atacgccctt tatgcaccgg caatacaagc gatgttccca
    12241 gcattgagga tttgatatga gaaggcatat cgtctgctcc ctcatagtca tgctcataat
    12301 ttccgttgtc gggaacggtg cggaggaaaa aacgctccat gtcgtggcgt acggtgggat
    12361 cgcagttctc attaagtgtc agagaggcgg aggtatgttg cagcaacaga tgcagtaagc
    12421 cgatgttaac gcgcggcata tcagccagct gattcagaat ttcatccgtt accagatgaa
    12481 acccacgaga tttggcgcta agcgtgagcg tcttttgata ccacatgtgc tgctccttga
    12541 taaaactctc ttaatcagtt tgcagcaaga cagcgaaagg ataaaggtgt gattaaaaaa
    12601 acagcattcg ggagagcatc acgctctccc gctctgtcag tattctgaat tgacgatcac
    12661 ctcttcacca aacgcacccg cttgtggcaa gggtttgtag gtagagttgg aggcgcgcag
    12721 aatgcggata ccacgagcgc cgacatcgcg tgcggcggta atatcattat cagaatcgcc
    12781 ataaaaaatt cggatatttt tatcctgcag ccattgcgat tttgtatttt gccctggttt
    12841 atcgcccgca aagatcaccg gattcatgtt ggtggcagga atatgaaaat tatccgccag
    12901 cgtttttgaa accgtttctg ttttcgtcgg gctacgacca gtcacaaaga agatcgcgtc
    12961 accgcggcgt acatgcatat caatcagctg gcgagcgacc tcttttggaa tgctgaattc
    13021 atcccagcca ttgttcattt tttcccagaa cacaggattt ttcagataat cttcgctttc
    13081 tggcgagaag gtttttttgc cgcgccagaa gcccggactg gaaaaaagta ccgtgtcatc
    13141 gatatcaaac cccaccgcca ttggcggacg ccctgcgagg ctattttcaa tttgtgcgac
    13201 cgaaacccaa tgaatgggtg cctgttcagc aagcctggca acgttagtcc cagggttaag
    13261 cggtgaagga gatgaggcca gggcaacagc ggaactgttt agagcgaaca ataagcaaac
    13321 ggcactgatt gcctgtgtga tcttgcgcat atttttccct aaatagtcag tatgttgaaa
    13381 ctttttattg tgagatttgt tgcaaaaacc atctgaccat aacgccagct gccggggaaa
    13441 ggaaggatta tctgcggttt ttgtgatgaa aagcaggatg attatattta acccagtaaa
    13501 tacgttcctg tctttttttg tataaaaaat gtttattact cgatgtaagg atacattaat
    13561 tttacgttta ttatgatgaa tcctcggcaa atgagcgaaa tttgatagaa catttatctg
    13621 ctgtacgatt taatgaactt aatgatacag cattacaaaa acaatcgaag tttataaaga
    13681 tgatttctga ttgaccagcc ccctacccta caatggtgat taattttatt actcgcgatg
    13741 gagatgatga tatgaatata tcatatgtga atagcaacaa aacgacatct t
//
LOCUS       DAPHKZ010000119        13737 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.119, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000119 DAPHKZ010000000
VERSION     DAPHKZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13737
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.119"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..594
                     /locus_tag="RH288_003649"
     CDS             <1..594
                     /locus_tag="RH288_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032665.1"
                     /translation="LFIMAICMAMVLLFLYINKDNIKVIYSLKINQTTPGILVSCDSN
                     NNFACQTTMTEDVIQRITTFFHTSPDVKNREIRLEWSGDKRALPTAEEEISRVQASII
                     KWYASEYHNGRQVLDEIQTPSAINSELYTKMIYLTRNWSLYPNGDGCVTISSPEIKNK
                     YPAAICLALGFFLSIVISVMFCLVKKMVDEYQQNSGQ"
     gene            complement(837..1532)
                     /locus_tag="RH288_003650"
     CDS             complement(837..1532)
                     /locus_tag="RH288_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HDV4032666.1"
                     /translation="MDNRGEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLNQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGAENISQAEQAKVGVVYAEYGLTESGGVVLFSAAERGRSLSLLP
                     EYSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     gene            complement(1525..2952)
                     /locus_tag="RH288_003651"
     CDS             complement(1525..2952)
                     /locus_tag="RH288_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="HDV4032667.1"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFARTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDNVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQEKKNG"
     gene            complement(2963..3682)
                     /locus_tag="RH288_003652"
     CDS             complement(2963..3682)
                     /locus_tag="RH288_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HDV4032668.1"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAA
                     KVAARMQDLTSFIVNKLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     gene            complement(4209..5063)
                     /gene="rclR"
                     /locus_tag="RH288_003653"
     CDS             complement(4209..5063)
                     /gene="rclR"
                     /locus_tag="RH288_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RclR"
                     /protein_id="HDV4032669.1"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFLAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSRETLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     gene            5289..6614
                     /locus_tag="RH288_003654"
     CDS             5289..6614
                     /locus_tag="RH288_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HDV4032670.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRMLGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
     gene            6723..6959
                     /locus_tag="RH288_003655"
     CDS             6723..6959
                     /locus_tag="RH288_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV4032671.1"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     DTIADIARKYNASSWKVTSMRIDNNSTATAVLYK"
     gene            6971..7564
                     /gene="rclC"
                     /locus_tag="RH288_003656"
     CDS             6971..7564
                     /gene="rclC"
                     /locus_tag="RH288_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species resistance protein
                     RclC"
                     /protein_id="HDV4032672.1"
                     /translation="MEKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSAREILKQRSNESSSTLKTEY"
     gene            complement(7723..7851)
                     /locus_tag="RH288_003657"
                     /pseudo
     CDS             complement(7723..7851)
                     /locus_tag="RH288_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308365.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            8154..9005
                     /locus_tag="RH288_003658"
     CDS             8154..9005
                     /locus_tag="RH288_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV4032673.1"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLTAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
                     YRHRDYWDLANIFPSFLIRQQQKTECRLINFPETPIFGNSFKYDIEVSNKSPDEEVKL
                     RRHHLARCMKNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCEYADMPKEWTTTRGLY
                     ASFRYEGNWENYPDWVRNIYLIELPARGLARVNGSDIERFYYNEDFVEKDGNDVVCEI
                     FIPVRPV"
     gene            complement(9145..13401)
                     /gene="fdeC"
                     /locus_tag="RH288_003659"
     CDS             complement(9145..13401)
                     /gene="fdeC"
                     /locus_tag="RH288_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001635811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like adhesin FdeC"
                     /protein_id="HDV4032674.1"
                     /translation="MSHYKTGHKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDSDATRNFITGMATA
                     KVNQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLAKQLDTDSIRE
                     RRVLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLK
                     NVQWEAPSLLAEGGKITGQGSQWQVTLPAYRPGKDNYYAISAVAYDNKGNASKRVQTE
                     VVITGAGMSADRTALTLDGQSRIQMLANGNEQRPLVLSLRDAEGQPVTGMKDQIKTEL
                     AFKPAGNIVTRSLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     FVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTAKDAYDNPVTSLTPEAPSLAGAAAVGSTASGW
                     TNNGDGTWTAQITLGSTAGELEVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLIAKDAHGNTISGLSLSASLTGTASEGATVSSWTEKGDCSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKAPTVKMTTELTFTV
                     KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVATLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDSYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGEHSITASVNNAQKTVTVKF
                     KADFSTGQATLEVDGSTPKVANDNDAFTLTATVKDQYGNLLPGAVVVFNLPRGVKPLA
                     DGNIMVNADKEGKAELKVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTTATISSIE
                     VIGNRAVADGKTKQTYKVTVTDANNNLLKDSDVTLTASSENLVLDPKGTAKTNEQGQA
                     VFTGSTTIAATYTLTAKVEQANGQVSTKTAESKFVADDKNAVLAASPERVDSLVADGK
                     TTATMTVTLMAGVNPVGGSMWVDIEAPEGVTEKDYQFLPSKADHFSGGKITRTFSTSK
                     PGVYTFTFNALTYGGYEMTPVKVTINAVAAETENGEEEMP"
BASE COUNT         3576 a         3426 c         3024 g         3711 t
ORIGIN      
        1 ctttttatta tggctatatg tatggctatg gtgctgttgt ttctgtatat caataaagac
       61 aatataaaag tgatttacag cctaaaaata aaccagacaa cgccaggtat acttgttagc
      121 tgtgatagca ataataattt tgcctgtcag actacaatga ctgaagatgt tattcagcga
      181 attactacat tttttcacac cagcccagat gtcaagaaca gagaaataag gctggaatgg
      241 tcaggagata agagagcttt accaactgct gaagaggaaa tatctcgcgt gcaggcctct
      301 attatcaaat ggtatgcgtc agaatatcat aatggcaggc aagttctcga tgagatacaa
      361 acgccttcag caattaacag tgagctttat acaaaaatga tatacctgac caggaactgg
      421 tcattgtatc cgaacggtga tggctgtgta actataagct caccagaaat aaaaaataaa
      481 taccctgctg ccatttgcct ggctctggga ttttttctaa gcattgtaat ttctgtaatg
      541 ttttgccttg tcaaaaaaat ggtagatgaa taccaacaaa actctgggca gtaataaaca
      601 acattctgat agagagtgcc tgtataaagc tgaagtgaca atgaccggga agggaacccg
      661 ttttcaggaa tggatgcctg tctttttcac tgtaaatatc ctggcattgg taataccagg
      721 atatttacag aagagcagca taaccatgac ggaacggggt taagtcaggt tgtcctaaac
      781 gctattttca acctcgtatg ccttcttcag gtttatgtcc agacttcata tctctctcaa
      841 caatcctcaa taatcagata caccgctttc accgggccat gaactccgac gactttgata
      901 agctcaatat ccgccgttga actggggccg ctaatgatgt taatgcagga aggcattcgt
      961 tcaccggcct gcgctttctg atgcaatttt tctgcgagtt gcgctacacg cggcaggata
     1021 gtgcttttac gcaggataaa aagagaatat tccgggagca ggctcaatga acgcccgcgc
     1081 tcggcggcgg aaaaaagaac cacgcctccc gattcggtta aaccatattc agcatacaca
     1141 acacccactt tagcctgctc tgcctgcgag atattctcgg cacctttcgc cggatcccaa
     1201 acaacggcat tgcattcctg ctgcaaacgt tcgctaatcc ccaattcctc cagcctcgtg
     1261 tcaccgctaa tcacgaccga ctgatctccc agctctttac acagacgtat tgcagcttct
     1321 gccgccttcg cctcgctggt cagctcacag cgcgtcaaca taacatcgct ggcaaactga
     1381 ataaacgcgt cacagcgctg ctgttggtta agttgggtaa gccgctcgtt agcatagttg
     1441 ttaagcggcg catcttctgc ttgcggttca agtcgcagcg ggcgacccag tgcctgagca
     1501 acgttattca aaaattcgcc tcgattatcc attctttttc tcctgcgcct gatgtttctt
     1561 aaaccaacta cggaaactct ctccgtcagc ttcaggaaga tcgcgtgctt ccatccagtc
     1621 gctaatcgcg ccaaatttga gtggtgtttt gccgccattg ataaaccagc ttgccgcatg
     1681 agcaccggcc atcatcccga ctttccacaa tcctggatga ctattggcat aagcgaacat
     1741 ttttatcgcc cgttgctctg cttttgcggt gatccctttt tcagccatca cccgacgatg
     1801 acgcaaaatc agttttgaca gcggaatacg caccggacac acgttgtcac aagctgtgca
     1861 taaagagcag gcgtagggta aatctttaaa atctttatag ccgccaagta gcggagaaat
     1921 caccgcacca attggccctg gataaataga gccatatcca tgaccgccaa tatggcgata
     1981 tgccggacaa gtattcatac aagccccgca gcgaatacag cgcagcacat cccgaaattc
     2041 agaggccagc acctcagaac gcccgttatc gacaataacc agatgaaact cttcaggacc
     2101 atcaacgtgc ccagcttcgc gcggtcctgt cagccaggtg ttgtatcccg tcaaacgtgc
     2161 accaacggca ctgcgcgcca gcatggtgat caatacatct acctcggcaa acgtgggggc
     2221 aatacgctcc attcccatca ctgcaatatg cgttttaggc agcgtggtac acattcgcgc
     2281 attaccttca ttggtcacca ggcataccga accggtctct gccaccgcga aattacagcc
     2341 ggtaatacct atttcagcac tgaggaaatc ttcgcggatt ttttgccgga tgaataaggt
     2401 catcgcttca ggcgtttccg gcccctcata gcccagacgt tcgtgtagca ctcgacggat
     2461 ctgatggcga tctttatgaa ttgccgggac cacaacatga gatggcggat cttgatccag
     2521 ctggagaata tattcaccca gatcggtttc aatcacctga atgccagcat cctgcaacac
     2581 atgattgaca ccaatctctt cggtcaccat cgatttagat ttcaccacct tccgggcatt
     2641 tttgcgttgg gcaacctgta aaatgtagcg ggtagcgtct tctttggttc ttgcaaaata
     2701 gacgtgaccg ccgttttgcg tcactttttc tgagagctgg tacagataag cgtcgagatt
     2761 actcagaaca tgatcacgta tctgggcggc ccgatcgcgc cactcctccc agtgccccaa
     2821 ttcatcgacc attttttgcc gatttgcccc aatacgctgc tgcgcgtttg ccaccgcttt
     2881 gcgcatgatc ggatcttcaa tttgctgacg gatgcgtgtc ttaaaatctg tattactggt
     2941 tttgatcgac atctttatat cctcagcggc tcatcaacac ttcagcaata tgcatcactt
     3001 tgactttctg cccttcccgt tgtaatcgcc cactgatgtt tagcaggcaa ctcacgtcag
     3061 caccaattaa atactcaggg cggacttcca tcaggtgcgc aaccttttct ttcaccatct
     3121 cgccggatat ttcggccatt ttgaccgaga acgtgccgcc aaatccgcag caggtatcct
     3181 gttcagcaaa ggtcaacagc tccagtccac gcacattttt cagcagcgta agtggctcgt
     3241 ccttcactcc cagcttacgg gccaggctac aagatgggtg atacaccgct ctcccttgca
     3301 aactggcacc tacatcgact acccctaatt tattaacaat aaaagaggtg agatcctgca
     3361 tacgcgcggc aacctttgcg gcacgtgatg cccattcagg ttcatccgcc agatacgtcg
     3421 ggtaactttt tacggcatag gtgcaagagc cagccggtga aataatggga tcgtcgttat
     3481 cctccagtgc ggcgatcaga tttttcatcc ctggaatcgc ttctttgata taaccgctat
     3541 tgatcgcagg ctgaccgcag catccctgtt tctccgggaa atttacgcga cagccgagtt
     3601 tttccagtag cagcacggag tctcgtgcca ttcttgattt cagggcgtca ccaatacagg
     3661 tgacaaagaa attgacattc acaactaata ctccattact tcatgcccat ttatgcccga
     3721 tgtttccccc ccaccggggg atcaatcatc aataaatatg gcgttctttt ttaattggct
     3781 agcaacatac tacccctcat ttgtatgaca aatgataatc tttcatccaa acgtcaaatg
     3841 caataactaa ttttatttct ttcggcatcg ctcacatttt atggggaaat cgacgatcat
     3901 ttttggcata agaaatccat ttaaaaatgg ctacatccct tatacctatt cagagctact
     3961 tattcagggg ttattgagat atacactgat ggtgtacaaa aaaatcaccg acaataatca
     4021 cgtatcaagt aatagtcggg attttattta attgaagcaa tttagtttgc atttttattt
     4081 aaaaactgag ctagagtcca tcagaaaaaa tatataaagc ccaaaccacc gttggaaata
     4141 gaaatagttg aaaggctcac aactcccgga atgcggatta tctttgccct gatttctggc
     4201 ggttttattc agggtgcaag ctgtctgacc ctttcccgat attctcccgg ggtacaacca
     4261 aactcgcgga caaacgcctt gtgaaaagat gattcactgg catagcctac tgactcagcg
     4321 atcaccacaa cagggagcgt ttcccgggaa aacatctggg ccgctatttg tagacgcaac
     4381 tttgttaata cagccagcgg cgtggttccg gaaacatcac ggaaaagctg ggcaaaactt
     4441 gcccgggaca tgtgagcgat gctggccagc gattcgacgg tccaggcgtg tcctggcatt
     4501 tccagcattt gctgtattac cgcaccaaga cgtggatgca gaagcaaact gagaatgttt
     4561 ttctcagtat taacctgtgc aatccactca cgcaccgcga gggtaaagaa tgtagcgcag
     4621 atctggctac acagtgcatc cactcccggc attgccgatc tggattcctg ttgtaaaaac
     4681 gggatcgcct ccctcagcca gttatattcc acgctgtggt taaccggtgc taaaaacagc
     4741 gtttccggca aagacgttaa aaaataacgc gccgaatgtt gcaaccgaag agtgccgcag
     4801 acaatacagg tcgattcatt atcgacatga ctcaggcgat gagctgaatt ttgtggtagc
     4861 aggaccacat ttcccgggcg taatgtaaaa atctcccccg tcggcatttc cagcttcgcc
     4921 gctccttgcg ttaacgcatg ccaacgaata accgataatt ccccggcacc atgtggaagc
     4981 tgccagtcac ttcctaacac gcaattctta tcgatcgttc cttgtggagc gttaagcatc
     5041 aacaaacggc taagggcatc catatcagac tcctgagtgg tttttgatta caaacaccaa
     5101 caatcttagt aaataactaa tctaatacca tcaaatagtt aatcatgatt tttgttttgt
     5161 gattctgatt aagaaaaaga aaatatcaga cgataagaca aaatatcaag cgttgtgaag
     5221 aaatgttatt tgctcttttg cgtctatagt catgatgtca aatgaacgcg tttcgacagg
     5281 aaatcatcat gaataaatat caggcagtga ttattggttt tggcaaggct ggaaaaacat
     5341 tagccgtcac gctggcaaaa gcaggttggc gagtggctct catcgaacaa tcaaatgcaa
     5401 tgtatggcgg gacctgtatt aatatcggct gcatcccaac caaaacattg gttcatgacg
     5461 cacagcagca cacagatttt gtccgtgcca tacagcgtaa aaatgaagtg gttaattttt
     5521 tacgtaataa gaattttcat aatcttgcgg atatgcccaa tatcgacgtg atcgacggcc
     5581 aggcggagtt tatcaataat catagcctgc gtgttcatcg gcctgaggga aatctggaaa
     5641 ttcatggcga gaaaattttt attaataccg gtgcacaaac cgtggttccg ccaattcctg
     5701 gaattaccac cacgccagga gtatatgaca gcaccggatt acttaatcta aaagaattgc
     5761 ctgggcattt aggtattttg ggcggcggat atattggcgt tgagttcgcc tctatgttcg
     5821 ctaattttgg cagcaaggta accattttag aagcagcttc gctgtttttg cctcgggaag
     5881 atcgggatat tgctgataat atcgcgacga ttttacgcga tcagggcgtc gatattatcc
     5941 tcaatgccca tgtggagcga atcagtcacc atgaaaatca agtgcaagtg catagcgagc
     6001 acgcccaact ggcggtggat gcactgttaa tagcttccgg tcgtcaaccg gctaccgctt
     6061 cgttacatcc agaaaatgcc ggtatcgcag taaacgagcg cggggcaatt gtcgttgaca
     6121 agcgattaca taccaccgca gacaatattt gggcgatggg agatgttacc ggcgggctgc
     6181 aatttactta catatcactg gatgattacc gcattgtacg tgatgagtta ctgggtgaag
     6241 gcaaacgtag tactgatgat cggaaaaatg tgccttattc cgtatttatg acaccgcccc
     6301 tgtccagggt tggtatgaca gaagaacaag ccagagagag tggtgctgat attcaggtgg
     6361 tgacattgcc tgtagctgca attccgcgtg ccagagtgat gaatgatact cgtggggtat
     6421 taaaagcgat tgttgataat aaaacccaac gtatgttagg ggcatcactg ctgtgtgttg
     6481 actcccacga gatgatcaat atagtgaaaa tggtgatgga tgccgggctg ccttatagca
     6541 tattacgcga tcagatattt actcatccgt cgatgagcga atcactcaat gatctatttt
     6601 cattagtcaa ataaactcaa aatcagacgc cagaacaaat attctggcgt ctcagagaaa
     6661 agaatcttat taattctctg ttactctata acttcttaat cacttcattg atggtatttt
     6721 atatgtttaa aaaatctgtt ttatttgcaa cactattatc tggcgttatg gcattttcca
     6781 ccaatgcaga tgataaaata attctgaaac atatcagcgt ctcgtcagta tcagcatcac
     6841 cgacagttct ggaggatacc attgctgata tagccagaaa atataatgct tcatcctgga
     6901 aagtcacatc gatgcgaatt gataataatt caaccgcaac agcagtattg tataaataag
     6961 gatgttcaca atggaaaaat acctgcacct gttaagtcgg ggagataaaa ttggcctgac
     7021 attgattcgt ctgagtattg caattgtttt tatgtggatt gggttattaa agtttgtccc
     7081 ttacgaggca gacagcatta caccattcgt cgcaaacagt ccactaatgt cgttctttta
     7141 tgaacacccg gaagactata aacagtatct gactcacgaa ggcgaataca aaccagaagc
     7201 aagggcatgg caaacggcca ataataccta tggtttttcc aacggtcttg gcgtcgtgga
     7261 ggtgattatt gctctgctgg ttttggctaa tcctgtcaat cgctggttag gtttattggg
     7321 aggactgatg gcatttacca cgccgctggt aacactctca tttttaatca ccaccccgga
     7381 ggcatgggta cccgcattgg gtgacgctca tcatggtttc ccttatttat ccggtgctgg
     7441 tcgcctggta ttgaaagata ctctgatgct ggcaggtgca gtcatgataa tggcagattc
     7501 ggcgcgggaa attcttaaac aacgcagtaa tgaatccagt tcaacgttaa aaactgaata
     7561 ttgataatcc gaacactgtc tgttgttcac tttttcaggc gtcaggcccc ctttctgatg
     7621 atgaagcctg acgccatatt accggagata tgacagagtg aagatcaata tcactccctg
     7681 ttaaaaggtt tttgtcgtct taggtaaaat acatgattaa tatcaatcat gtatttttac
     7741 agcaagacaa ccacgaacaa attcaggatt aaaatgtttt accgactccc caacataacc
     7801 caaatcaagc gaactaattt gtgccatttc tttatctgtc agtgagaaat cgatttttga
     7861 tgggcatctg caatactctg aagcagacta tacggaaaat tccactgtca gtccctccat
     7921 taggcatgaa caatgagtct acgttaaaac gtaacctcaa agtagtatgt ggattttgat
     7981 atcacttatg caaaaaattc attaataatg taggactgaa acctctctat tttcggggac
     8041 aacgaagcag acgctaccag tgcttttgcc ttcgcccttg ctatttttga tacacttagg
     8101 gcccagggta taacgaaaat gtgcgatatg acaaagaatt aacggagaat gagatgatca
     8161 ggcagaagat tctacagcag ctcctggagt ggattgagtg caatcttgag caccctattt
     8221 caatcgaaga tatcgcacag aaatctggct acagcagacg caacatccag cttctgttcc
     8281 gaaatttcat gcatgtgcct ttgggagaat acattcgcaa acgaaggctt tgtcgtgccg
     8341 ccattcttgt ccggctcacc gcgaaatcta tgcttgatat tgcactctct ttgcattttg
     8401 attcacagca gtcattcagc cgcgaattta aaaagttatt cggctgctct ccccgtgaat
     8461 accgccaccg tgattattgg gatctcgcaa atatcttccc ttctttttta atacgtcaac
     8521 agcaaaagac ggagtgtaga ttaatcaact ttcctgagac acctattttt ggcaactcat
     8581 ttaaatatga cattgaagtg tcgaataaat caccggatga agaagtcaaa ctacgacgtc
     8641 atcatttagc cagatgtatg aagaatttta agacggatat ctatttcgtt tccacgtttg
     8701 aaccgtcaac aaaatcggtc gatttgctca cggttgaaac ttttgctggt acggtatgtg
     8761 aatatgctga catgccaaaa gagtggacaa cgacccgagg actttatgcc tctttccgtt
     8821 atgaaggaaa ctgggaaaat tatcctgact gggtgcgtaa catctatctg atagagttac
     8881 ctgccagggg gttagccaga gtgaacggca gcgatattga gcgcttttat tacaatgaag
     8941 atttcgtaga aaaggatggc aatgatgttg tttgcgaaat ttttattccc gttcgtccgg
     9001 tttagttggt cactatctct tattgagttt tatccttgcc tgatactatt taatcagtat
     9061 caggcaaggt attcagtgaa taatggcgtt gaatatttca acaccattat tctttattag
     9121 atcgtaactt tcatactatt caaattatgg catctcctcc tcgccatttt cagtctctgc
     9181 agcaacggcg ttaattgtca ccttcacagg cgtcatttcg tacccgccat acgtcagtgc
     9241 gttgaatgtg aacgtataga cacctggctt gctggtacta aatgtacgcg tgattttccc
     9301 acctgagaaa tggtcagcct tcgacggcag gaattgataa tccttctccg tcactccttc
     9361 cggagcctca atgtcgaccc acatacttcc tcctacggga ttgactcccg ccatcagggt
     9421 aaccgtcatt gttgcagtag tcttcccgtc cgccaccaga gaatctacac gttctggaga
     9481 tgcggcgagc accgcgtttt tatcatccgc gacgaattta gattcagcag ttttcgtcga
     9541 tacctgaccg ttggcctgtt ccactttcgc cgtgagtgta tatgtcgctg cgatagtggt
     9601 agagccggtg aaaacagcct gtccttgctc attagttttc gccgtccctt taggatccag
     9661 aactaaattt tccgagctgg cagtcagcgt cacgtcgcta tccttcaaca ggttgttatt
     9721 ggcatcagtc accgtaactt tatacgtctg tttggttttg ccatccgcca ctgcacggtt
     9781 gccaatcacc tcaatactgg agatggtcgc cgtagtctta tcggccacaa acgttacaga
     9841 ctgcgcattc gaaggctggt catttcctgc cgacgccgtg atctcatacg ttccggcagt
     9901 cacggagacc actttcagtt ccgctttacc ctccttgtcg gcgttcacca tgatattacc
     9961 gtctgcaagc ggtttgacgc cccgaggcag attaaagacg accacagcgc caggcagaag
    10021 gttgccgtat tgatccttaa ccgttgccgt cagcgtaaag gcatcattgt cgtttgccac
    10081 ttttggcgtg ctgccatcaa cctccagggt cgcctgaccg gtactgaaat ccgccttgaa
    10141 tttcaccgta accgtcttct gagcattatt cactgaggcc gtgatgctgt gttcccccgc
    10201 aaccgttgac ataagctcaa tgtccacttt ccctgccgca ttggttgtta ctgtattccc
    10261 cgtcttgctg gtcacaccct gcggtaaagt cagcgtaact tcttgcccct gtaacgggtt
    10321 accatagctg tccacgacgg tcagggttat ctggttagca gactgtccat tagccagttg
    10381 gttattaacc ttcactgtca tatcacgaat ctcagcctta gatgcgtcac ctgcaacgtt
    10441 cagcaccagt ggctgagcaa cggcattttg gccgttcact cgcggcatca cagacaactg
    10501 acccgcggca gatcccagcg ttaaggtcgc cacgtagacc ccattacctt tctctgtcca
    10561 gtttcctgct gaaggacgct cactccccgt gctggcggca ccgctaaaca ctggtgcatc
    10621 tggcttcagc ccggtgaccg ggttcccgta cgcatccttc acggtgaagg tgagttccgt
    10681 cgtcattttg acggtcggag ccttattgtc cgcaacaagc gtagagttcg ctgatgacat
    10741 ctctccggcg atgaccgtca actgcgcggc ttcggtggct gctggctggc cgttgaagag
    10801 cggcatgaca cgaagctcgc ccgtctttcc gcctgtagtt aacgtagcaa cataggaaca
    10861 gtcacctttt tcggtccaac tggaaacggt cgccccttca gaggcggtcc ccgtcaaact
    10921 tgccgacaac gaaagaccac tgatagtgtt gccatgtgca tcttttgcaa taagcgtcac
    10981 ggttgtgctt tcgccggctt ttacgtgatc ttctgcgaca gagactttcg actggtttga
    11041 agataacgca tcagccacca cggttacttt tgccgcattt gctgccgcat cctgtccatt
    11101 tagcttcggc ataacttcta attcacccgc cgtagagccg agagtaatct gcgcagtcca
    11161 cgtcccatca ccattatttg tccagccaga tgccgtagaa cctacagcag cggcacccgc
    11221 taatgacggc gcttccggcg tgaggctggt cacagggttg tcataggcat cttttgccgt
    11281 ccagattgcc gtaactgtac cgccaaccac cggtttatca ggattcaggg tgatggacga
    11341 atgtgctgca tcaagcggac cggcaacaaa cttcagcgtt tgttgtaatg tgcccagctg
    11401 atactgctcg ctgaaagcac gcacaacaac gtttccggca cgggtcgaag aaaccgtggc
    11461 gctgtaaacg cctggtttta tttccgaaat ggcaccaacg gttacaccat tagtgtcttg
    11521 cggaacaaat cgcaagcggc tggcttctcc cgtcaccgga ttaccctcgg agtccaccgc
    11581 agtcaacgtc aacgtatagg cttgctgacc atcagcaacc acatcacctg acggctcgtt
    11641 agcgctcagg gtggagtttg ccacatccat catcgtggcc cgcagttctg cagtgacggt
    11701 tttgctcatg ccatcaacgc taacagtaat cgttgcctca cctgactgcg ttccggtagt
    11761 aaagacagac tgatacaccc ctgcttcagt ttcggtgaac tcacccagtg ttggctttgc
    11821 ctgtgattta gtggccttca gggaacgagt cacaatattt ccagccggtt tgaaggctag
    11881 ttcagtcttg atctgatctt tcatgcccgt gactggctgc ccctcggcgt cgcgcagaga
    11941 cagcaccagc ggtctttgct cattaccgtt agcaagcatt tgaatacggc tctgaccgtc
    12001 aagcgttaac gccgtgcgat cggcgctcat acctgctccg gtaatgacca cctctgtctg
    12061 cacgcgtttt gaggcattgc ctttgttatc gtaggcaacc gcagaaatcg cataataatt
    12121 gtctttgcct ggacgataag ccgggagcgt tacttgccac tgactaccct gaccggtaat
    12181 tttgccaccc tcagccagta atgacggcgc ttcccactgc acatttttca gtccgtgagt
    12241 tgctttgctg accacaagcc ccagggaaag tgtctgacca cccttacctt caatacgttc
    12301 aggcagagca atacggatca cttcagattt gcggtactca agaacgatgt tgttattacg
    12361 ctcaaccagg tcatagcggc tgcctgccag tacccgacgc tcgcgaatgc tgtctgtatc
    12421 gagttgtttc gccagaggtt cgccaatccg ataattaact tccaggccaa agcgagtgtc
    12481 attctcacca ctcttgccct gcttatgccc ggcgctcagt gtcagaagag gcactggcgt
    12541 ataggtcacc tcggcagaaa tagcatgcgg gtctttctgg cgcttatctt taccaaacag
    12601 cccgacttca tcgccataat actgttcata catcaggctt gcgccaagct gcggccaggc
    12661 gggtaaatag ccctcagcac gaatatccca gccattcgcc gggcgttcct gataatcctc
    12721 aatatccggc gattttttcc agccagaagc ccgaatataa ccattggcgc tcagtttcag
    12781 ataatcgcgc cagtattccg caccaacacc aatgcgggta tgactacggg ataaatcatg
    12841 atcgataaaa gtattcaccc ccgccatcca gtcatttcct gaaaaatgac gccagccaaa
    12901 accaatattt gactgagtac gatcgtctgt acgatgtatt gccccctgag tgaacaacat
    12961 atttgtcggc gtatcataaa tcggataaag catttccagc gaagaatcct tcagcgagaa
    13021 atctttatcg acattcagtt tgacgcgcgc agtaccatat ttcccgagcc actcctgtat
    13081 ttcctggtta actttagctg tggccattcc ggtaataaag ttacgtgtcg catcgctatc
    13141 tggctgactg cttaaaaatg tcccggcatt tgcggcaaac gacgcgacat ttttctccac
    13201 gttattatca gcagttaccg tagtatttcc catgctcaac cgtggctgaa ccgcatgctg
    13261 cgcacgtgcc gccattactg gggtaaaggt gacagcgagt ggaaaaagaa cctgaacaga
    13321 gatatttgcc cacgccacgc agcgggccag aactgaataa cgaaatcgtg gttgtttatg
    13381 acctgtttta taatgtgaca ttgagataat ttcctgatga acgaattaac gaacataggc
    13441 agacacaaat aatggcgtct gcttgtcaga aaaaccgggg atttcccgat ttccttttcc
    13501 gcagaaaagg aaataccttt atgtaagaaa gtgcaccgcc acctaatata tccagtgcct
    13561 atagccactc atcaggtggt tgggcgcggg attatatttt tatttatggg ggaaaattta
    13621 gctttttgtg caagtcatta aatagatacc taagttatat ttcttactct gcggacagtg
    13681 aataattcac tattcagagt gaataacaat gacctgcctt taattaaaac tattgga
//
LOCUS       DAPHKZ010000120        13516 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.120, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000120 DAPHKZ010000000
VERSION     DAPHKZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13516
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.120"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(16..1281)
                     /locus_tag="RH288_003660"
     CDS             complement(16..1281)
                     /locus_tag="RH288_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001642584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDV4032675.1"
                     /translation="MALTDLKVRTAKPADKQYKLTDGGGMHLLVHPNGSKYWRLQYRY
                     EGKQKMLALGVYPEITLADARVRRDEARKLLANGVDPGDKKKNDKVEQSKARTFKEVA
                     IEWYGTNKKWSEDHAHRVLKSLEDNLFAALGERNIAELKTRDLLAPIKAVEMSGRLEV
                     AARLQQRTTAIMRYAVQSGLIDYNPAQEMAGAVASCNRQHRPALELKRIPELLTKIDS
                     YTGRPLTRWATELTLLIFIRSSELRFARWSEIDFEASIWTIPPEREPIPGVKHSHRGS
                     KMRTTHLVPLSTQALAILKQIKQFCGAHDLIFIGDHDSHKPMSENTVNSALRVMGYDT
                     KVEVCGHGFRTMACSSLIESGLWSRDAVERQMSHMERNSVRAAYIHKAEHLEERRLML
                     QWWADFLDANRERFISPFEYAKINNPLKQ"
     gene            complement(1469..1553)
                     /locus_tag="RH288_003661"
     tRNA            complement(1469..1553)
                     /locus_tag="RH288_003661"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1517..1519),aa:Leu,seq:caa)
     gene            1749..2768
                     /gene="ahr"
                     /locus_tag="RH288_003662"
     CDS             1749..2768
                     /gene="ahr"
                     /locus_tag="RH288_003662"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase Ahr"
                     /protein_id="HDV4032676.1"
                     /translation="MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSD
                     LSMIDNEWGFSQYPLVAGHEVIGRVVALGSATQDKGLQVGQRVGIGWTARSCGHCDAC
                     ISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
                     LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVN
                     SRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLI
                     AGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVV
                     LKADF"
     gene            2898..4400
                     /locus_tag="RH288_003663"
     CDS             2898..4400
                     /locus_tag="RH288_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HDV4032677.1"
                     /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLA
                     ESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLTRLKNIGVNDWQPHANPVVVWDIFG
                     EKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQY
                     IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKG
                     VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP
                     QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRTFTPKDQKAV
                     KAAAQTMRVNPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTE
                     DERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASAEQQNNPAVKGKEVAVDDGILG
                     GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR"
     gene            complement(4519..5601)
                     /gene="lptG"
                     /locus_tag="RH288_003664"
     CDS             complement(4519..5601)
                     /gene="lptG"
                     /locus_tag="RH288_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HDV4032678.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIIGALLPSASFFLISLWLLMRKS"
     gene            complement(5601..6701)
                     /gene="lptF"
                     /locus_tag="RH288_003665"
     CDS             complement(5601..6701)
                     /gene="lptF"
                     /locus_tag="RH288_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HDV4032679.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTAL
                     LRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTV
                     NLIYLALAIVLNLWDTVPVRRLRASFSRKGAV"
     gene            6968..8479
                     /gene="pepA"
                     /locus_tag="RH288_003666"
     CDS             6968..8479
                     /gene="pepA"
                     /locus_tag="RH288_003666"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDV4032680.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE"
     gene            8833..9276
                     /gene="holC"
                     /locus_tag="RH288_003667"
     CDS             8833..9276
                     /gene="holC"
                     /locus_tag="RH288_003667"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HDV4032681.1"
                     /translation="MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACE
                     DEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK"
     gene            9276..12131
                     /gene="valS"
                     /locus_tag="RH288_003668"
     CDS             9276..12131
                     /gene="valS"
                     /locus_tag="RH288_003668"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDV4032682.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQK
                     LERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRN
                     EDEVRKENNLGADVVLRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFN
                     QTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVL
                     PADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEG
                     FVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL"
     gene            complement(12187..13383)
                     /locus_tag="RH288_003669"
     CDS             complement(12187..13383)
                     /locus_tag="RH288_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709944.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF898 domain-containing protein"
                     /protein_id="HDV4032683.1"
                     /translation="MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLP
                     WALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLVFVFCYFAILMTVSADMPLVGCV
                     LTLLLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGFWWVTFFLPILMAIGMGTV
                     FFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFK
                     VKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQ
                     RKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCAL
                     VVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLARISRGIM
                     PSLPFL"
BASE COUNT         3474 a         3462 c         3490 g         3090 t
ORIGIN      
        1 atttgcccgg gatgattact gttttaatgg attattaatc tttgcatatt caaatggact
       61 gataaatctt tctctgtttg catccagaaa atcggcccac cactgtagca tcagtcgccg
      121 ttcttccaga tgttctgctt tatggatata cgcagccctc actgaatttc gctccatgtg
      181 actcatctga cgttcaacag catcacgaga ccacaaacct gattcgatca atgaactaca
      241 ggccattgtt cggaaaccat gaccacagac ctcaactttt gtatcatacc ccatgacccg
      301 taacgcacta tttactgtat tctcactcat gggcttgtgc gaatcgtgat caccaataaa
      361 tatcaagtca tgagccccac aaaactgttt tatctgcttt aaaattgcaa gggcttgcgt
      421 tgaaagaggc actagatgcg ttgtacgcat ttttgagcct ctatgggaat gtttcactcc
      481 aggaataggc tcccgctccg gtgggatagt ccatatagac gcttcgaaat cgatctctga
      541 ccaacgagca aaacgcagct cactggaccg aataaagatc agcaaagtaa gttctgtcgc
      601 ccatcgggtt agcggcctac cagtatagct atctattttt gtaagcaact cagggatgcg
      661 ctttaattca agcgcgggac gatgttgtcg attacaggaa gcaaccgccc cagccatctc
      721 ttgtgccggg ttataatcaa ttaacccact ttgcactgca tagcgcatga tggcggtagt
      781 acgctgttga agacgagcag ccacttcaag acgtccagac atctccacgg ctttaatagg
      841 tgctaataaa tctcgagttt ttaactcagc gatattacgt tcaccaagcg ctgcaaaaag
      901 attatcttcc agacttttta gcacacgatg ggcatgatct tctgaccact ttttattggt
      961 gccataccac tcgatcgcga cttctttaaa ggttcgtgct ttactctgtt caaccttatc
     1021 atttttcttt ttatctcccg gatcgacgcc attcgcaagc agcttacgcg cctcgtcacg
     1081 acgtactctg gcatccgcta gtgtgatttc aggataaacc ccaagtgcca gcatcttttg
     1141 ctttccctca taacggtact gcaaacgcca gtacttagaa ccatttggat ggacaagcag
     1201 atgcataccg ccaccatcag tcagcttata ttgcttatcc gctggcttgg ctgttctgac
     1261 tttgagatct gttaatgcca tgcgtattcc ctccctgttg gtacaagcat tatcgaaccg
     1321 gaaataccat catctgtacc aacatgtgtt ggtagatgta cgttgatatc agttgacctt
     1381 gagagagtta atatagcggg aaaggtagat aaatactgga ttttaggcat aaaaaaaaga
     1441 cctcagttga ggtctattta tatacttttg gtgccgaagg ccggactcga accggcacgt
     1501 atttctacgg ttgattttga atcaactgcg tctaccgatt tcgccacttc ggcactgaag
     1561 aggtatgcgg aaaacgttgt ggattatacc tgtcgcacgc caccatgcaa gcgccagctt
     1621 gcacccacct cgctaagtgc tgaaattttc agcattacac tcagcgatat gtaacctttg
     1681 tcacactcca ggcaccccgc cctgccatgc tctacacttc ccaaacaaca ccagagaagg
     1741 acccaaaaat gtcgatgata aaaagctatg ccgcaaaaga agcgggcggc gaactggaag
     1801 tttatgagta cgatcccggt gagctgaagc cacaagatgt tgaagtgcag gtggattact
     1861 gcgggatttg tcattccgat ctgtcgatga tcgataacga atggggattt tcacaatatc
     1921 cgctggttgc cgggcatgag gtgattgggc gcgtggtggc actcgggagc gccacgcagg
     1981 ataaaggttt gcaggtcggt cagcgtgtcg ggattggctg gacggcgcgt agctgcggtc
     2041 actgcgacgc ctgtattagc ggtaatcaga tcaactgcga gcaaggtgcg gtgccgacga
     2101 ttatgaatcg cggtggcttt gccgagaagc tgcgtgcaga ctggcaatgg gtgattccgc
     2161 tgccagaaaa tattgatatc gagtccgccg ggccgctgct gtgtggtggt atcacggtct
     2221 ttaaaccact gttgatgcac catatcactg ctaccagccg cgttggggta attggtattg
     2281 gcgggctggg gcatatcgct ataaaacttc tgcacgcaat gggatgcgag gtgacggcct
     2341 ttagttctaa tccggcgaaa gagcaggaag tactggcgat gggtgccgat aaagtggtga
     2401 atagccgcga tccgcaggca ctgaaagccc tgtcggggca gtttgatctc attatcaata
     2461 ctgtgaacgt cagcctcgac tggcagcctt attttgaggc gctgacctat ggcggtaatt
     2521 tccatacggt cggtgcggtt ctcacgccgc tgtctgttcc ggcctttacg ttaattgcgg
     2581 gcgaccgcag catctctggt tctgctaccg gcacgcctta tgagctgcgt aagctgatgc
     2641 gttttgccgc ccgcagcaag gttgcgccga ccaccgaact gttcccgatg tcgaaaatta
     2701 acgacgccat ccagcatgta cgcgatggta aagcgcgcta ccgcgtggtc ctgaaagccg
     2761 acttctgatc cctttgccgg gtgcctgtcg cccggcactt aaatctcttt ggaaggcgtc
     2821 tcgcaatctg ctgaatttag cggtgaagag tgcacagcct ttgcctatac tccaggcagg
     2881 aaactggagg aaatctcatg agcgaacccc tgttaattgc ccgcacgccg gacacagaac
     2941 tgtttttact gccgggaatg gctaaccgtc acgggctgat tactggcgca acggggacgg
     3001 gtaaaaccgt tacgctgcaa aaactggcag agtcattgtc ggaaatcggc gtgccggtgt
     3061 ttatggctga tgtgaaaggc gatctgaccg gtatcgcgca ggcaggaacg gcgtcggaaa
     3121 aactgctcac aaggcttaaa aatatcggcg tcaatgactg gcaaccgcat gccaatccgg
     3181 tggtggtgtg ggatatcttt ggcgagaaag gccatccggt gcgggcgacg gtttcggatc
     3241 tggggccgct gttgctggcg cggctgttga atctcaacga tgtgcagtct ggcgtgctga
     3301 atatcatctt ccgcattgct gacgatcagg ggctgttact gctcgacttt aaagatttgc
     3361 gggcgattac ccagtacatc ggcgataacg ccaaatcttt ccagaatcag tacggaaata
     3421 tcagtagcgc atcggttggt gccatccagc gcgggctgtt gtcgctggaa cagcaaggcg
     3481 cagcacactt ctttggtgag ccgatgctgg atatcaaaga ctggatgcgc accgatgcca
     3541 acggtaaagg cgttatcaat atcctcagcg ccgagaagct ttatcagatg ccgaaactgt
     3601 atgccgccag cctgttgtgg atgctctcgg agttgtatga acaattgccg gaagcgggcg
     3661 atctggagaa accaaaactg gtgtttttct tcgacgaggc acatctgctg tttaacgatg
     3721 caccgcaggt actgctggat aagattgagc aggtgataag gcttattcgc tcaaaaggcg
     3781 tgggcgtctg gttcgtttcg caaaatccgt ccgatattcc ggataacgtg ctcggccagc
     3841 tcggtaatcg cgttcaacac gctttgcgga cttttacgcc caaagatcag aaagcggtaa
     3901 aagctgcggc gcaaaccatg cgggtcaatc cggcatttga taccgaaaag gcgattcagg
     3961 aactgggcac cggcgaggcg ttgatctctt ttctggatgc gaaaggaagc ccttctgtgg
     4021 tggaacgggc gatggtgatt gcgccttgtt cgcggatggg accggtgacg gaagatgagc
     4081 gtaatggctt gattaatcac tctccggtgt atggcaagta cgaggatgac gtggaccggg
     4141 aatccgccta tgagatgttg caaaaaggcg tacaggcaag cgccgagcag caaaataatc
     4201 ctgccgtgaa agggaaagag gtggcggtgg atgacggcat tcttggtgga ttgaaggata
     4261 ttttgtttgg cactaccgga ccacgcggcg ggaagaaaga tggtgtggtg caaacaatgg
     4321 cgaaaagcgc cgcccgccag gtgacgaatc agattgtacg cgggatgttg gggagtttgc
     4381 tgggagggag aagaaggtaa gtcaggcgcg atctgtcccc ctcaccctaa ccctctcccc
     4441 aaaggggcga ggggaccgat cgaactcgta tttgacttta tcaacaatgt gaaagggagc
     4501 tttcgctccc ttgcttggtt acgattttct cattaacagc cacaggctga ttaagaagaa
     4561 gctggcgctt ggcaacagtg cgccgataat cggcgggatg ccgtaaacca acgtcagcgg
     4621 gccgaagatc tggtccagta cgtagaagac aaaaccgaag ctgataccgg tgaccacacg
     4681 cacgcccatc ggtacgctac gcagtgggcc aaagatgaac gacagcgcca tcagcatcat
     4741 caccgccacg gatagcggct ggaagatttt gctccacatg ttgagctgat aacgtccggc
     4801 atcctgaccg ctcgacttca gatacttcac atagttgtgc aaaccgctaa tggagagtgc
     4861 atccgggtcc agcgccacca cgcccagttt gtctggcgtg aggttggttt tccaggtacc
     4921 gctcaccgtc tgcgaaccgg tgatctgttt cggattggtc agatcagatt catccacctg
     4981 cgacagacgc cagactttat gttccgggtc aaacttcgcg gtagcggcat agcgtacgga
     5041 ttgcagacga cgattctcgt taaaggcata aatgctgatg ccacctaact cttcgtcacc
     5101 tttaacccgc tcaatgtaga cgaagttgtt gccatctttc gcccataagc cttgctgggt
     5161 agagagcaac gagccgccgt acatcgcctg cgcacggtag ttacgcgcca tctgctcgcc
     5221 ctgcggcgcg acccattcgc caatcgccat cgtcagcaag accagcggaa tggcggtttt
     5281 catcaccgac agcgccacct gcatacgggt aaaaccagaa gcctgcatca ccaccagttc
     5341 gctgcgctgc gccagcatcc caagaccaag caacgcccca agcagagccg ccatcgggaa
     5401 gaagatttgc acatctttcg gcacgctcag caaggtatac attcctgcgc ctaacgcgtc
     5461 gtaactcccc tgcccggctt ttttcaactg atcgacaaat ttgataatgc ccgacagcga
     5521 caccagcatg aacagcgtca tcatgatggt ggtgaaaata gttttaccga tatagcggtc
     5581 aagtacgcca aaaggttgca tcacaccgct cctttacgcg aaaaactggc gcgcaggcgg
     5641 cggaccggca cggtgtccca aaggttgaga acaatcgcca aagccagata aatcaggtta
     5701 acggtccaca tccacagcgt cgggtccagc ttacctttac cgccgttcga tttcagggag
     5761 gtctggatca ggaagaaaag tagatacagc agcatggctg gcagcatcga cagtacgcgt
     5821 ccctgacgtg ggttaaccac gctcagcggt acgaccataa gtgccatcat aaacacggtg
     5881 aataccaacg tgatacgcca gttcagttct gcgcgagcac gatcggtgtc agtgttccac
     5941 aatgtgcgca tgtccatctg gtcggtatcg ttcgggtcga gcgccaccgc ctggtgacca
     6001 atgatcgcct gataatcctg gaaatccgta atgcggaaat cacgtaacag tgcagtgcct
     6061 tcgaagcgcg ttccctggtt gagagtgacg acctgggagc cgtcgcgcag ctgggttaaa
     6121 tgtccggaat cggccaccac cacagaagga cgtgcattac cttttggtcg aatttgcgcg
     6181 aggaacacat ctttgaaatc gctgccgtca acgctttcga tgaacagcac cgaactgcca
     6241 ttagtcgctt gctggaattg cccttgcgcc agcgccgcca tgccagggtt cgctttcgct
     6301 tctgctaaca cttcatcctg atgacgcgat gaccacggtc ccgcccacat cacgttaacc
     6361 gccgcgacga ttgccgtgaa taccgcaagg atcattgccg ctttcaccag aaccgctttg
     6421 ctcaggccgc aggcatgcat taccgtaatt tcactttcgg tatacagttt gcccagcgtc
     6481 atcagcagcc cgaggaacag gcttaatggc aggataagct gcgccatttc cggcacgccc
     6541 aacccgagaa gggagagcac cagattcgcc ggaatatcgc cgtcaaccgc tgcgccgagg
     6601 atcctcacta acttttgaca gaagaagatc aaaagcaaga tgaagagtat cgccagctgg
     6661 cttttgagcg tctcccgcac cagatatctt atgattatca ctttaaatac gcccgtaaaa
     6721 actcgtcttt tgcaggattt tagcttgttt catggcttaa acgtcattta ttctcttgag
     6781 tcgtcgaaat cgtcgctaag ataattatac tcaacggatt cacctctcag attttgttct
     6841 gacgtgccaa tgccgtaata acgttaagat taacacgaag tcatcgcaac agcggacatg
     6901 agttacgaaa gcttgcaatt ctatctgtag ccaccgccgt tgtctttaag attcaggagc
     6961 gtagtgcatg gagtttagtg taaaaagcgg tagcccggag aaacagcgga gtgcctgcat
     7021 cgtcgtgggc gtcttcgaac cacgtcgcct ttctccgatt gcagaacagc tcgataaaat
     7081 cagcgatggg tacatcagcg ccctgctacg tcggggcgaa ctggaaggaa aaccggggca
     7141 gacattgttg ctgcaccatg ttccgaatgt actttccgag cgaattctcc ttattggttg
     7201 cggcaaagaa cgtgagctgg atgagcgtca gtacaaacaa gtcattcaga aaaccattaa
     7261 tacgctgaat gatactggct caatggaagc ggtctgcttt ctgactgaac tgcacgttaa
     7321 aggccgtaac aactactgga aagtgcgtca ggctgtcgag acggcaaaag agacgctcta
     7381 cagtttcgat cagctgaaaa cgaacaagag cgaaccgcgt cgtccgctgc gtaagatggt
     7441 gttcaacgtg ccgacccgcc gtgaactgac cagcggtgag cgcgcgatcc agcacggtct
     7501 ggcgattgcc gccgggatta aagcagcaaa agatctcggc aatatgccgc cgaatatctg
     7561 taacgccgct tacctcgctt cacaagcgcg ccagctggct gacagctaca gcaagaatgt
     7621 catcacccgc gttatcggcg aacagcagat gaaagagctg gggatgcatt cctatctggc
     7681 ggtcggtcag ggttcgcaaa acgaatcgct gatgtcggtg attgagtaca aaggcaacgc
     7741 gtcggaagat gcacgcccaa tcgtgctggt gggtaaaggt ttaaccttcg actccggcgg
     7801 tatctcgatc aagccttcag aaggcatgga tgagatgaag tacgatatgt gcggtgcggc
     7861 agcggtttac ggcgtgatgc ggatggtcgc ggagctacaa ctgccgatta acgttatcgg
     7921 cgtgttggca ggctgcgaaa acatgcctgg cggacgagcc tatcgtccgg gcgatgtgtt
     7981 aaccaccatg tccggtcaaa ccgttgaagt gctgaacacc gacgctgaag gccgcctggt
     8041 actgtgcgac gtgttaactt acgttgagcg ttttgagccg gaagcggtga ttgacgtggc
     8101 gacgctgacc ggtgcctgcg tgatcgcgct gggtcatcat attactggtc tgatggcgaa
     8161 ccataatccg ctggcccatg aactgattgc cgcgtctgaa caatccggtg accgcgcatg
     8221 gcgcttaccg ctgggtgacg agtatcagga acaactggag tccaattttg ccgatatggc
     8281 gaacattggc ggtcgtcctg gtggggcgat taccgcaggt tgcttcctgt cacgctttac
     8341 ccgtaagtac aactgggcgc acctggatat cgccggtacc gcctggcgtt ctggtaaagc
     8401 aaaaggcgcc accggtcgtc cggtagcgtt gctggcacag ttcctgttaa accgcgctgg
     8461 gtttaacggc gaagagtaat tgcgtcaggc aaggctgtta ttgccggatg cggcgtgaac
     8521 gccttatccg acctacacag cactgaactc gtaggcctga taagacacaa cagcgtcgca
     8581 tcaggcaatg ctgttattgt cagatgcggc atgaacgcct tatccgacct acacagcacc
     8641 gaactcgtaa gcctgataag acgcggcagc gtcgcatcag gcaatgctgt tattgtcgga
     8701 tgcggcgtga gcgccttatc cgacctacac acagcactga actcgtaggc ctgataagac
     8761 acaacagcgt cgcatcaggc gctgcggtgt atacctgatg cgtatttaaa tccaccacaa
     8821 gaagccccat ttatgaaaaa cgcgacgttc taccttctgg acaatgacac caccgtcgat
     8881 ggcttaagcg ccgttgagca actggtgtgt gaaattgccg cagaacgttg gcgcagcggt
     8941 aagcgcgtgc tcatcgcctg tgaagatgaa aagcaggctt accggctgga tgaagccctg
     9001 tgggcgcgtc cggcagaaag ctttgttccg cataatttag cgggagaagg accgcgcggc
     9061 ggtgcgccgg tggagatcgc ctggccgcaa aaacgcagca gcagcccgcg cgatatattg
     9121 attagtctgc gaacaagctt tgcagatttt gccaccgctt tcacagaagt ggtagacttc
     9181 gttccttatg aagattctct gaaacaactg gcgcgcgaac gctataaagc ctaccgcgtg
     9241 gctggtttca acctgaatac ggcaacctgg aaataatgga aaagacatat aacccacaag
     9301 atatcgaaca gccgctttac gagcactggg aaaagcaggg ctactttaag cctaatggcg
     9361 atgaaagcca ggaaagtttc tgcatcatga tcccgccgcc gaacgtcacc ggcagtttgc
     9421 atatgggtca cgccttccag caaaccatca tggataccat gatccgctat cagcgcatgc
     9481 agggcaaaaa caccctgtgg caggtcggta ctgaccacgc cgggatcgct acccagatgg
     9541 tcgttgagcg caagattgcc gcagaagaag gtaaaacccg tcacgactac ggccgcgaag
     9601 ctttcatcga caaaatttgg gaatggaaag cggaatccgg cggcacgatt acccgtcaga
     9661 tgcgccgtct cggcaactcc gtcgactggg agcgtgaacg cttcaccatg gacgaaggcc
     9721 tgtccaatgc ggtgaaagaa gttttcgttc gtctgtataa agaagacctg atttaccgtg
     9781 gcaaacgcct ggtaaactgg gatccgaaac tgcgcaccgc tatctctgac ctggaagtcg
     9841 aaaaccgcga atcgaaaggt tcgatgtggc acatccgcta tccgctggct gacggtgcga
     9901 aaaccgcaga cggtaaagat tatctggtgg tcgcgactac ccgtccagaa accctgctgg
     9961 gcgatactgg cgtagccgtt aacccggaag atccgcgtta caaagatctg attggcaaat
    10021 atgtcattct gccgctggtt aaccgtcgta ttccgatcgt tggcgacgaa cacgccgaca
    10081 tggaaaaagg caccggctgc gtgaaaatca ctccggcgca cgactttaac gactatgaag
    10141 tgggtaaacg tcacgccctg ccgatgatca acatcctgac ctttgacggc gatatccgtg
    10201 aaagcgccca ggtgttcgat accaaaggta acgaatctga cgtttattcc agcgaaatcc
    10261 ctgcagagtt ccagaaactg gagcgttttg ctgcacgtaa agcagtcgtt gccgcagttg
    10321 acgcgcttgg cctgctggaa gaaattaaac cgcacgacct gaccgttcct tacggcgacc
    10381 gtggcggcgt agttatcgaa ccaatgctga ccgaccagtg gtacgtgcgt gccgatgtcc
    10441 tggcgaaacc ggcggttgaa gcggttgaga acggcgacat tcagttcgta ccgaagcagt
    10501 acgaaaacat gtacttctcc tggatgcgcg atattcagga ctggtgtatc tctcgtcagt
    10561 tgtggtgggg tcaccgtatc ccggcatggt atgacgaagc gggtaacgtt tatgttggcc
    10621 gcaacgaaga cgaagtgcgt aaagaaaata acctcggtgc tgatgttgtc ctgcgtcagg
    10681 acgaagacgt tctcgatacc tggttctctt ctgcgctgtg gaccttctct acccttggct
    10741 ggccggaaaa caccgacgcc ctgcgtcagt tccacccaac cagcgtgatg gtatctggtt
    10801 tcgacatcat cttcttctgg attgcccgca tgatcatgat gaccatgcac ttcatcaaag
    10861 atgaaaatgg caaaccgcag gtgccgttcc acactgttta catgaccggt ctgattcgtg
    10921 acgacgaagg ccagaagatg tccaaatcca agggtaacgt tatcgacccg ctggatatgg
    10981 ttgacggtat ttcgctgcca gaactgctgg aaaaacgtac cggcaatatg atgcagccgc
    11041 agctggcgga caaaatccgt aagcgcaccg agaaacagtt cccgaacggc attgagccgc
    11101 acggcaccga tgccctgcgc ttcaccctgg cggcactggc gtctaccggt cgtgacatca
    11161 actgggatat gaagcgcctg gaaggttacc gtaacttctg taacaagctg tggaacgcca
    11221 gccgctttgt gctgatgaac acagaaggtc aggattgcgg cttcaacggc ggcgaaatga
    11281 cgctgtcgct ggcggaccgc tggattctgg cggagttcaa ccagaccatc aaagcgtacc
    11341 gcgaagcgct ggacagcttc cgcttcgata tcgccgcagg cattctgtat gagttcacct
    11401 ggaaccagtt ctgtgactgg tatctcgagc tgaccaagcc ggtaatgaac ggtggcaccg
    11461 aagcagaact gcgcggtact cgccatacgc tggtgactgt actggaaggt ctgctgcgcc
    11521 tcgcgcatcc gatcattccg ttcatcaccg aaaccatctg gcagcgtgtg aaagtacttt
    11581 gcggtatcac tgccgacacc atcatgctgc agccgttccc gcagtacgat gcatctcagg
    11641 ttgatgaagc cgcactggcc gacacagagt ggttgaagca ggcgatcgtt gcggtacgta
    11701 acatccgtgc agaaatgaac atcgcgccgg gcaaaccgct ggagctgctg ctgcgtggtt
    11761 gcagcgcgga tgcagaacgt cgcgtaaatg aaaaccgtgg cttcctgcaa accctggcgc
    11821 gtctggaaag catcaccgtg ctgcctgccg atgacaaagg tccggtttcc gttactaaga
    11881 tcatcgacgg cgcagagctg ctgatcccga tggctggcct catcaacaaa gaagatgagc
    11941 tggcgcgtct ggcgaaagaa gtggcgaaga tcgaaggcga aatcagccgt atcgagaaca
    12001 agctggcgaa tgaaggcttt gtcgcccgcg caccggaagc ggtcatcgcg aaagagcgtg
    12061 agaagctgga aggctatgca gaagcgaaag cgaagctgat tgaacagcag gctgttattg
    12121 ccgcgctgta atcaaaacac agtaatgaaa acgaaggccg gagcatgctc cggccttttt
    12181 tatctcttac agaaatggta aagaaggcat aattccccgt gaaatcctgg ctaagaagcc
    12241 tttatctggt tgttcttctt tattgattaa aggaaggtca tccaaatcgc ccagcaaata
    12301 cgtatttttt gcctgccagt caatcatcca tattttcagc agtggataag ccagaccgcc
    12361 cgtaatcccg gatatcacca ccaacgcaca catgcgataa agcataccgt ggtacgttaa
    12421 agttgagcga aaacgaatac gcccatcatt cagtgacagg ttgctcataa aatgatttcg
    12481 caacgacacc gttaaataac tggtgctaac agcaatccca aaataataga ttaactgcgc
    12541 gattatcatt ttacgttgca tttccataaa ttgctgtaaa ttctcaatat catcatttgc
    12601 atacacagaa ctatcatacg catttaatat ttgatcgaag ataatataac cagcaacagc
    12661 gagaaaaggt aataaagcta aaaatgcgag aatggcatat tttatacaat acgtagtatc
    12721 taatttcacc ttgaaacgat gtataccgaa actggtattg ctccagagaa aactcattac
    12781 caggctatat aaagtaccat taaaaatacc aatggaaaca ataccaacta ttgccatcag
    12841 aaccacagat ataataacac tacttgaact attggcatgt agcatctttg tcgagataaa
    12901 gaaaacagtc cccatcccaa tggccattaa aatcggcaag aaaaaggtta cccaccagaa
    12961 ccctttcata gagcaattaa aactaaatct tacgccgttg agactggtca tcaaggcctg
    13021 ataacgcagt ccttttgctg ccataaatat aagcaaaacc aacagtaaca aagtcaaaac
    13081 acagccaaca agtggcatat ctgctgacac tgtcattaag attgcgaaat agcaaaaaac
    13141 aaaaacaaga caactaacaa aaacattccc accagtaatt ccataagaaa atcgttgtcc
    13201 gttaacttcc atattagcat agagataacg cttacatttc attaatgccc atggcaaata
    13261 gatacctagc gttataatcg ttaacaacac attcaccaca caaataagaa aatatctctc
    13321 acctgtacca tgaaaaacaa acgaatggga cggaacatcc atttcattaa taacttgagc
    13381 cataaaaatt ccctgaatta aaaaatccat tgatataatt tatatataca gacagcaaaa
    13441 tgttctgcca cgttacaata ctcttatcag taataggctg gcaaaaactt tattacttta
    13501 taagtcgctt gcgcac
//
LOCUS       DAPHKZ010000121        13468 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.121, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000121 DAPHKZ010000000
VERSION     DAPHKZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13468
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.121"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            71..901
                     /locus_tag="RH288_003670"
     CDS             71..901
                     /locus_tag="RH288_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418745.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfZ/YjiC family protein"
                     /protein_id="HDV4032684.1"
                     /translation="MSMPLSNALQSQIITDAHFLHHPIVDSEFTRKLKYARMDSENIY
                     LPPLTRGNNHNYDGKSVVEIRKLDISKEPWPFNYVTGACRESDGITTTGRMLYRNLKI
                     TSALDEIYGGICKKAHATTELAEGLRLNLFMKSPFDPVEDYTVHEITLGPGCNVPGYA
                     GTTIGYISTLPASQAKRWTNEQPRIDIYIDQIMTVTGVANSSGFALAALLNANIELGN
                     DPIIGIEAYPGTAEIHAKMGYKVIPGDENAPLKRMTLQPSSLPELFELKNGEWNYIGK
                     "
     gene            complement(1042..1815)
                     /gene="uxuR"
                     /locus_tag="RH288_003671"
     CDS             complement(1042..1815)
                     /gene="uxuR"
                     /locus_tag="RH288_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HDV4032685.1"
                     /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLD
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDNSGSQNTDSPDANVCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA"
     gene            complement(2030..3490)
                     /locus_tag="RH288_003672"
     CDS             complement(2030..3490)
                     /locus_tag="RH288_003672"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HDV4032686.1"
                     /translation="MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHH
                     LLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALH
                     PEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
                     AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENV
                     TFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKV
                     GAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTVTNPAYRKAAFALMMQE
                     QAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQN
                     GGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLS
                     GIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL"
     gene            complement(3571..4755)
                     /gene="uxuA"
                     /locus_tag="RH288_003673"
     CDS             complement(3571..4755)
                     /gene="uxuA"
                     /locus_tag="RH288_003673"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDV4032687.1"
                     /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEE
                     ILKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAE
                     RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKA
                     IIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEE
                     HRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SR"
     gene            5095..6438
                     /gene="gntP"
                     /locus_tag="RH288_003674"
     CDS             5095..6438
                     /gene="gntP"
                     /locus_tag="RH288_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease GntP"
                     /protein_id="HDV4032688.1"
                     /translation="MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGM
                     DLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQL
                     SVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
                     PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVD
                     MNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVA
                     FVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSH
                     GNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLAT
                     AAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA"
     gene            complement(6681..7583)
                     /gene="fimH"
                     /locus_tag="RH288_003675"
     CDS             complement(6681..7583)
                     /gene="fimH"
                     /locus_tag="RH288_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria D-mannose specific adhesin FimH"
                     /protein_id="HDV4032689.1"
                     /translation="MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVN
                     LAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSS
                     YPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNS
                     DDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYL
                     SGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTAN
                     YARTGGQVTAGNVQSIIGVTFVYQ"
     gene            complement(7603..8106)
                     /gene="fimG"
                     /locus_tag="RH288_003676"
     CDS             complement(7603..8106)
                     /gene="fimG"
                     /locus_tag="RH288_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimG"
                     /protein_id="HDV4032690.1"
                     /translation="MKWCKRGYVLAAILALASATIQAADVTITVNGKVVAKPCTVSTT
                     NATVDLGDLYSFSLMSAGAASAWHDVALELTNCPVGTSRVTASFSGAADSTGYYKNQG
                     TAQNIQLELQDDSGNTLNTGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQAVI
                     SITYTYS"
     gene            complement(8119..8649)
                     /gene="fimF"
                     /locus_tag="RH288_003677"
     CDS             complement(8119..8649)
                     /gene="fimF"
                     /locus_tag="RH288_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimF"
                     /protein_id="HDV4032691.1"
                     /translation="MRNKPFYLLCAFLWLAVSHALAADSTITIRGYVRDNGCSVAAES
                     TNFTVDLMENAAKQFNNIGATTPVVPFRILLSPCGNAVSAVKVGFTGVADSHNANLLA
                     LENTVSAASGLGIQLLNEQQNQIPLNAPSSALSWTTLTPGKPNTLNFYARLMATQVPV
                     TAGHINATATFTLEYQ"
     gene            complement(8659..11295)
                     /gene="fimD"
                     /locus_tag="RH288_003678"
     CDS             complement(8659..11295)
                     /gene="fimD"
                     /locus_tag="RH288_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher FimD"
                     /protein_id="HDV4032692.1"
                     /translation="MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLVVACAFAAQAPLSS
                     ADLYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSE
                     QGIVPCLTRAQLASMGLNTASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTI
                     PQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIG
                     AWRLRDNTTWSYNSSDRSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGI
                     NFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTIND
                     IYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEK
                     PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD
                     DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV
                     IQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGL
                     NTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMS
                     HDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI
                     GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTD
                     WRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL
                     LMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV
                     ANYQLPPESQQQLLTQLSAECR"
     gene            complement(11362..12087)
                     /gene="fimC"
                     /locus_tag="RH288_003679"
     CDS             complement(11362..12087)
                     /gene="fimC"
                     /locus_tag="RH288_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418736.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HDV4032693.1"
                     /translation="MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATR
                     VIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKKENTLR
                     ILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPP
                     DQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESTVKLPSDAG
                     SNITYRTINDYGALTPKMTGVME"
     gene            complement(12124..12663)
                     /locus_tag="RH288_003680"
     CDS             complement(12124..12663)
                     /locus_tag="RH288_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418735.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4032694.1"
                     /translation="MKRKRLFLLASLLPMFALAGNKWNTTLPGGNMQFQGVIIAETCR
                     IEAGDKQMTVNMGQISSNRFHAVGEDSAPVPFVIHLRECSTVVSERVGVAFHGVADGK
                     NPDVLSVGEGPGIATNIGVALFDDEGNLVPINRPPANWKRLYSGSTSLHFIAKYRATG
                     RRVTGGIANAQAWFSLTYQ"
     gene            complement(12728..13276)
                     /gene="fimA"
                     /locus_tag="RH288_003681"
     CDS             complement(12728..13276)
                     /gene="fimA"
                     /locus_tag="RH288_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HDV4032695.1"
                     /translation="MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAAC
                     AVDAGSVDQTVQLGQVRTASLAQEGATSSAVGFNIQLNDCDTNVASKAAVAFLGTAID
                     AGHTNVLALQSSAAGSATNVGVQILDRTGAALTLDGATFSSETTLNNGTNTIPFQARY
                     FATGAATPGAANADATFKVQYQ"
BASE COUNT         3278 a         3495 c         3248 g         3447 t
ORIGIN      
        1 ctctttttac tacagaaaaa tttatctatt tttctaaaca tcagtgaaat actcataaaa
       61 ggtaactatt atgtctatgc cattaagcaa tgcccttcag agtcaaatta ttacagatgc
      121 tcacttcctt catcacccaa tagtcgacag tgagtttaca cgtaaattaa aatatgcacg
      181 catggattcg gaaaacatct atcttccgcc tcttactcgt ggcaataacc ataattacga
      241 tggaaaaagc gttgtcgaaa ttagaaaact tgatattagt aaagagcctt ggccatttaa
      301 ttatgtgaca ggagcatgca gagaatccga tggtattaca acaacaggac gtatgctcta
      361 tcggaacttg aaaatcacct cagctttaga cgaaatatat ggtggcatat gtaaaaaggc
      421 gcatgctacc acagagttag cagaaggttt acggctaaat ttatttatga agagcccttt
      481 cgatcctgtt gaggactata cagttcatga aataacatta ggccctggtt gcaatgttcc
      541 tggttatgcc ggaaccacga taggatatat ttcaaccctt ccagcttctc aggcaaaaag
      601 atggaccaat gagcagccaa ggattgatat ctatattgat cagataatga cggtaacagg
      661 ggtagcaaat tcttccggat tcgcccttgc cgcattactt aatgctaata ttgagttggg
      721 taatgaccca ataattggta tagaagccta tcccggtacc gcggagatcc atgcaaaaat
      781 gggatataaa gttatcccgg gtgatgaaaa tgcaccactc aaacgtatga ctctgcaacc
      841 gtcatctctt ccagaactgt ttgaattaaa aaatggtgaa tggaattata ttggtaaata
      901 actaccagga agaatgagta ctaacattca ggttatacag atagctaaac aataccctgc
      961 aatttacaaa gtaatactcc ttgcgacttc ttaatttaag aaagcgcaag gaacgtttac
     1021 ccttgcgctt attataataa gtcaggcgtc gactttatcc agcggccatg aatcaaacag
     1081 atagccatca aaataaatat cgtcaacgtt cgagaattcc agcagacgtt gcttaacgtt
     1141 ttccagatgc tgccacattg ccagcttcgc cgctcgggca tcttttttga ttaacgcggc
     1201 gaggatctgt ttgtgatcgc ccaaccactc tttgcgatac aggctgtcat ccagatggct
     1261 gtgcaactgg atccacattg gattgttttc ccgccactgc caggactgac ggaacagctc
     1321 caccagcatg ctgttatgcg ttgcttcggc aatagcgaga tggaactgca tgtcaccgct
     1381 ttcgctgctg cccggcgcac tggaagccag ttcacgctct tccagttgca atgcctgacg
     1441 cattttgacg atatcttcgc gggtagcctg caaagcggca aactcggcga tgttgctctc
     1501 caataactgc cgcgcctgta acagctcaaa aggaccggca tcgttgcaga cgttggcatc
     1561 cggactgtct gtgttctggc tgcctgagtt atcaagaaca tagataccgg caccccggcg
     1621 tacttctacc agccctttga tctccagcat gatcagcgct tcacgtacca ccgtccgcgt
     1681 gacatcaagc atttctgcaa tttcacgctc cggcggcagc cgttcgccag gattgtacgg
     1741 cgtctttatg atcagatcgc ggatcatcgc cccgacttcc tggtaaggtc tttgcgcaga
     1801 ggtggcagat ttcatggtgt tgtgtccgtt aggtgcggtt aatcaaattt ttgccggatg
     1861 cggcgtgaac gccttatccg gcctacaacg ggcaatttta cggcccccgt taatctcaaa
     1921 ctataccatt agcactggaa gttggcacgt acaggtgggc aaaaaaacga aaactggtca
     1981 accaaatatc agtttgattg accagtaagt ctgtagggta atcagttagt tacagcgcag
     2041 ccacacactc gcgcgcaccg cgttcgcaca gctgctgata tgccgccgtc actgcgccaa
     2101 caaagtcggc attctgcggc agatcatcgg caaaaatacc gctcaggccc agcagcgctt
     2161 tcacgcggtc tgcgccctga tactgcgcgt tgatcttctg gaactccgcc agcatcgggt
     2221 cgaccacgtc aatggcatta ccctgctcat ccacgccctg ggtgtaacgc atccagccag
     2281 ccacgcccag cgccaggtga cgccagctgc cgccgttttg caggtgcaga cgcaccgggt
     2341 ccagcagacg ctgcggtaac ttctggctgc cgtccatcgc aatctgccag gtacggtgac
     2401 gcagagacgg gttgctgaaa cgctcgatca gcagcgtcgc ataggcgttc aggtctgtac
     2461 cttccggcat cgacagcgtt ggcgcttgtt cctgcatcat cagggcaaag gccgctttgc
     2521 gataagccgg gttagtcacg gtgtcggcaa tggtttcata gccgccgagg taaccgaggt
     2581 acgccagaaa agagtggctg ccgttcagca tacgcagctt catcatttcg aacggcacaa
     2641 cgtctgcaac gaactgtgcg cccactttat cccaatccgg gcgaccatta acgaagttat
     2701 cttcaatcac ccactgacgg aacggttcgc aggcaatggc gcacgggtcg taaacaccca
     2761 gctggtcagc aatttcctgt aaggtttctg gcgtcgccgc cggaacgatg cggtcaacca
     2821 tggtgcacgg gaaggtgaca ttttcttcaa tccatgccgc cagctgcggg tcacgcgcct
     2881 gagccagccc cagtaccgcg accttcgcca catgaccgtt ttcacgcacg ttatcgcagg
     2941 acatcaccgt aaacgctttc aacccttttt cacgacgcag acgcaacgct tcgacgatgt
     3001 aaccaatcgc ggacttcggc gcagtcgggt tttccagatc gtgcttgatc agcgggttat
     3061 tgagatccag ttgaccgctt gccgcatcag cgcagtagcc tttttccgtg accgttagag
     3121 agacaatcgc cgtttgcgga cgcgccatcg cgttgagaat accttcgcag ccatcgattt
     3181 ccggatgcag cgcttctttc atcgaaccga taattttcag ctcggtgctc tctgcgcctt
     3241 tttccgctac ggtgtacagc agttgctgtt ttttcaggtt ttcgatcagc acgcggtcgt
     3301 tgcctggcat caggttaact tcgcagatgc cccagtcgct gtcggtgctt tccagcagat
     3361 gatgggtata cagcgcctgg tgcgcgcggt gaaacgcccc gcaaccgaga tgcacaatgc
     3421 gtgattccag acgagaatga tcccatgacg ggcgggcaac cggcagattg ctgtcaacaa
     3481 tagtagtcat cgtaaactcc agaatccgtc ttcaaagagt gacggcaagg aagaaggaac
     3541 cggcacggcg cgcagccatg ccggtggata ttaacggcta aagaaagcgc gctggatcgc
     3601 cagttcgaca ccgcgaactt cggccaggcc tttcagacga ccaattgcgg agtaacctgg
     3661 gttggttttc ttcttcaggt cgtccagcat ctgatgaccg tggtccggac gcatcgggat
     3721 caagtcttct ttgccttccg ctttacgacg gtgttcttct tcaacaatcg ctttcaccac
     3781 ttcgtacata tcaacgtcac cgttcaggtg cgccgcttcg tggaaggttt tcgggttatc
     3841 ttcacgcatg gtggagcgca gatgggtgaa gtaaatacgc ggaccgaact gcttgatcat
     3901 atcaaccaga tcgttgtcag cacgcacgcc gtaggaaccg gtgcacatgg taaaaccgtt
     3961 tgccatgctg tttacggtat caaccatcca ctgcatatct tcaatggtgg aaacaatgcg
     4021 cggcaggccg aggatcgggc gcggcggatc gtccgggtga acagccatac gcacgccgac
     4081 ttcttcagct actggaataa tcgctttcag gaagacggca aagttttcgc gcagcttcgc
     4141 tttgtcgata tctttgtaca gctccaggtg tttacggaac tggtcgaggg tgtagccttc
     4201 ttccgcgccc ggaagaccag caatgatgtt acgggtcaga cgcgctttgt cttcatcgct
     4261 catagtggcg aagcgttcag ctgcctgagc aatttcttct tcggtgtaat ccgcttccgc
     4321 gcctgggcgt ttcaggatat gcatttcgaa tgcagcgaat tcgatctggt cgaagcgcag
     4381 agctttggag ccgtctggca gcacgtattc gaggtcagta cgggtccagt cgagcaccgg
     4441 catgaagttg tagcacacgg tgcgaatgcc acactgcgcc aggttgcgca gagtctgctg
     4501 atagttagcg atccactgct catagttgcc agtgtgggtt ttgatatctt cgtgaattgg
     4561 cacgctttct acgacagacc acaccaggcc tgcgtcttca atgatcgcct tgcgtttgag
     4621 gatctcttca acggaccata cttcgccgtt cgggatatgg tgcagcgcgg taaccacgcc
     4681 agttgcgccc gcctgacgga catcagctaa agaaaccgga tcgtttgggc cgtaccagcg
     4741 ccaggtctgt tccatgattt ttcctctttc acatagtggg ttccacagca aagagacgcg
     4801 gaaccctgga gttgtttagg tatccggatg aacaaccaga ccgcagccgt ggcgttgcat
     4861 cggatgagat ggcgtataag ttctaccttt tggtaagaca tgtcaacccg aattctgaaa
     4921 ttggttaacc acatcacaag aatttcactc tcatggttgt tgctgcaaat tgcagcaaag
     4981 ggtaatcgat ggttattgat cagaggatgt gacattcatc gcaacaatgg ttgaccaatt
     5041 tacataacat atcgcccaaa ataacaacgg ttcaaccagg taaggtaaaa cgttatgcat
     5101 gtgcttaaca ttctctgggt ggtattcggc attggtctga tgctggtact gaatttgaag
     5161 ttcaaaatca attcaatggt ggctttgttg gtggcggcgc tgtccgtcgg gatgctggcg
     5221 ggcatggatt tgatgtcgct gctgcacact atgaaagcgg gcttcggcaa cacgctgggg
     5281 gaactggcta tcatcgtggt gttcggtgcg gtcatcggta aattgatggt cgactccggc
     5341 gcggctcacc agatagcgca tacgctgctg gcgcgtctcg gtctgcgcta tgtacagctg
     5401 tcggtgatta tcatcggcct gatttttggt ctggcgatgt tctatgaagt ggcctttatc
     5461 atgttagcgc cgctggttat tgttattgcc gccgaagcta aaattccgtt cctgaaactg
     5521 gcgatcccgg cagtagcagc tgccactacc gcacattcac tgttcccacc gcagccgggt
     5581 ccggtggcgc tggtgaatgc ttatggcgcg gatatgggga tggtttatat ctatggcgta
     5641 ctggtgacga tcccaagtgt aatctgcgca ggtctgatcc tgccgaagtt cctcggcaat
     5701 cttgagcgcc caacgccatc attcctgaaa gcagatcaac cggtagatat gaataatctg
     5761 ccctctttcg gcgtttcgat tctggtgccg ctgatcccgg cgatcattat gatctctacc
     5821 accatcgcca atatctggct ggtaaaagat acccctgcct gggaagtggt taactttatc
     5881 ggttcctcgc cgattgcaat gtttattgcg atggtggttg cattcgtact ctttggcacc
     5941 gcacgtggtc atgacatgca gtgggtgatg aacgcttttg aaagcgcggt gaagagtatt
     6001 gcaatggtga ttctgatcat cggtgcgggt ggcgtgctga agcagaccat catcgacacc
     6061 ggcattggcg acaccatcgg catgttgatg tcccacggca atatctcgcc ctacatcatg
     6121 gcatggctga tcactgtgct aattcgtctg gcgacgggtc agggtgtcgt ttcggcgatg
     6181 accgccgccg ggattatcag tgctgcaatc ctagatccag caactggtca gctggttggc
     6241 gtgaatccgg cgctgctggt actggcgacg gctgcgggtt ccaacaccct cacccacatt
     6301 aacgatgcat ctttctggtt gttcaaaggt tactttgacc tgtcagtaaa agacacgttg
     6361 aaaacctggg gtctgctgga gctggtcaac tccgtggttg ggctgattat tgtgctgatt
     6421 attagcatgg tagcgtaaaa ggacaccaga gcctgccaat ggcaggctca gactgatgac
     6481 aaagtctaaa aatgtgcccg gacagtcccc tcgcccctcc ggggagaggg ttagggtgag
     6541 gggaacagac cagcaaagtg cgctttgttt atgccagatg cgacgctgac gcgtcttatc
     6601 tggcctacaa agggctaacg tgcaggtttt tagcttcagg taatattgcg taccagcatt
     6661 agcaatgtcc tgtgatttct ttattgataa acaaaagtca cgccaataat cgattgcaca
     6721 ttccctgcag tcacctgccc tccggtacgt gcataatttg ccgttaatcc cagactcacc
     6781 gccgaagtcc ctactgctcc taacgatacc gtgttattcg ctggaataat cgtaccgttg
     6841 cgcgtcaact gtacgccgac gccctgtgca ggtgaaaacg acgcggtatt ggtgaaaatc
     6901 gagttgcccg catctgcggt tgtgccggag aggtaatacc ccaggttttg gcttttcgca
     6961 caataaacgg taagaggaat tggcactgaa ccagggtagt ccggcagagt aacggtgaca
     7021 tcacgagcag aaacatcgca gccgccagta ggcaccacca catcattatt ggcgtaaata
     7081 ttccacacaa actggaaatc atcgctgtta tagttgttgg tctgtcgcaa aataagcacg
     7141 gcaattaatg agccagcttt aatcgccacc ccgcccgcac tgctcacagg cgtcaaataa
     7201 agcgccaccg gccacggctt atccgttctc gaattataaa caacgcgcgg cgtttcgctg
     7261 gtggtaggaa atggatagct actgccacta tattttacgg tcccggaaaa attagataac
     7321 acgccgccat aagccgagcc tcgttgcagt gtgacatagt ctgtaatggt ttccggataa
     7381 tcgttatggc aaaagatttg cgtcgaaaga tccacgacca ggttttgccc cacattcacg
     7441 acgggcgcaa ggtttacata aacattggcg ctgccaccgc caatagggat agcggtacca
     7501 ttggcggttt tacaggcgaa tgaccaggca tttaccgacc agcccatcag cagtacagca
     7561 aacagggtaa taactcgttt cattacaatc atctcttcgg gttcagctgt aggtataggt
     7621 gatgctaatc actgcctgaa tggttccctg agtggctccg ccatttactg tcaatgctct
     7681 gacctgtaac gggaagtgcg ctgattgtga ggaatcatcc acctgaactg ttttggttgc
     7741 gccagtattc aatgtgttgc cactgtcatc ctgtagctct aactggatgt tttgcgcggt
     7801 cccctggttt ttataatatc cggtactgtc ggctgccccg ctgaagctgg cagtgaccct
     7861 cgacgttccc accggacaat tagtcaactc aagcgcaaca tcatgccagg ccgatgccgc
     7921 cccggcagac ataagactga aagaataaag atcgccgaga tcaaccgtgg cattggtggt
     7981 ggaaaccgta cacggtttgg cgacgacctt accgttcacc gtgatggtga catcggctgc
     8041 ctgtatcgtc gcacttgcga gcgccaatat tgccgccaat acatacccac gtttgcacca
     8101 tttcatgagc atctccagtt actgatattc aagagtgaag gtagccgtgg cattgatatg
     8161 ccccgcagtg acaggcacct gtgtcgccat tagccgggcg taaaaattca gcgtatttgg
     8221 tttacccggc gtcagggtcg tccacgaaag cgcggacgat ggagcattaa ggggtatttg
     8281 attttgctgc tcattcagaa gctgtattcc cagtcccgaa gccgctgaca ccgtattttc
     8341 aagtgcaagc aggttggcat tgtggctatc tgcaacgcca gtaaacccaa cctttacggc
     8401 agaaacggca ttaccacagg gtgacagcaa aatacgaaat ggaacaacag gagtcgtcgc
     8461 gccaatgttg ttaaattgct tcgccgcgtt ttccatcaga tcaacagtaa aattggttga
     8521 ttcagcggcc acactacagc cgttatccct gacatagccg cggatagtaa tcgtgctatc
     8581 cgcagccaaa gcgtgactca ccgccagcca caaaaaagcg cacagaagat aaaaaggttt
     8641 gtttctcatc acgccccctt aacgacattc agctgatagc tgggttaata actgctgctg
     8701 actctctggt ggcagttgat aattggcgac acagtgagca ttttcctctt ctccccattt
     8761 cacctgaact tttcccgcta aaggcattcc gctgaggtaa acctgaccat tatccgcaac
     8821 aatgccgcta ctctggctac tctctgatgt caccatcgcc ccaaacggca gcggcttatt
     8881 attgtgggtc agcgtcatga gcagttttat cccaacgcgc gctttaaact ctgctcgcac
     8941 gatcgcccca cgagtgggaa caacgttagc aaccgcgtta tctaaatcga cgttatcagc
     9001 cagggtattg gtatccagcg ccactctatt ttcccgatat tcagtggcat aaggcagcac
     9061 ggcataacca cgccagtcgg tacgcacccc cgtctggttt tcgacttttg catcttttgc
     9121 gccaggcgct ttaacaagca ccaccgtatc gtttaacggc tgccccagcg ttacgccatt
     9181 ggcatgagcc agtaccccac cgctgactcc gtaatagagc tgcttaatat catcgctatg
     9241 gctgtaaccg atattggcat tgccgtaacc accgcgataa ttcagcgtgg cgtagcctgt
     9301 acttccgcta tttccatcgc ctcccccggc atagccggtt tgcacgctat agctgaggtt
     9361 gttgtcttcc agcaacgtac cgtatacacc agccagattg gtcatccgac cgttgagatc
     9421 gtgtgacatg ctgtagctgg cactggcatg tcgccactga gatttactgt cagaacgcag
     9481 ccagtggctg aaaggaatat tgacgttaag cgctaacatc tgatcccgtc ctttttgcca
     9541 ggcgtttttc gtcaggctat agctgagcgt ccagttgata tcttcgaacg cagtatttaa
     9601 tccagcctgg aattgctcat cgacattact cgttccccaa taagtttgat ggctaccact
     9661 caaatacagt gttgatgtgc gcccgagttg ctgagtaacg gtgagttgta atttcccgcg
     9721 tttgttataa gcgaggttgt aatagtcggt gaatttcggc ttaacctgaa taactccgtc
     9781 ctgtgtttcg atgttgtagc cattcattcg actgtatgtt gtatcagcga aattaaaata
     9841 tccgctggtc gaataacggt aacccactaa ctgaatattc gtgcctgatt cattgagcga
     9901 tttgttatag agaaaacgca ccgattgtcc gtcatgctga ctgtcatcgg gaagtgtgga
     9961 attagcctgc gtcatatcca cagacagagc gcccagtgcc cccatgtttt tcccgatacc
    10021 gaaattaaaa gcacgataac gatccgccag ttgcgttcca ccatatattg tccagccagc
    10081 cggaaggccg tggagtaatg tactctggaa aaagcggggt ttttcctgct gcgcatttcc
    10141 actacggtat tctcctgccg taatggaata acgagtatgc ccttcacgtt gcaaaagcgg
    10201 gactgacgaa tagggtacgg taaaaatctg cgtgctgccg tcagcctctt tgatcgttac
    10261 ctgcaagtca ccactattac ctgcggcata gatatcgttg atggtaaaag gccccggtgg
    10321 caccgtacta ttataaatgt catacccatt ttgtttaata gtgacctgtg cagtaccacg
    10381 agcaataccg tggatcaccg gggcaaatcc tctttgacta tcgggtaaca tattgtcatc
    10441 tgaggccaat tgtgcgccgc gaaagttaat accatcgaaa atatcgccct gagtataacc
    10501 atcacccagc gtcagccggg aacgtaacgg tattatgtct cgctcaagcc aggtattgat
    10561 atgctgccat ttatttttgc tacctgatga tctgtcgcta ctgttataac tccaggtggt
    10621 attgtcgcgt aaacgccacg caccaatatt taacccactc tgtaggttta aatatgcata
    10681 atggctgtta cccccaatcc gattctgtac actatttccg ctgaaattat aattgagcaa
    10741 tccggcatta ataccgggat cccataactc aggaggaata taaccacgcg cgcgattact
    10801 cataaatgcc tgagggatcg tcaggttcag tcgctgctga ccaacatcca gatgcgcagt
    10861 agcgtcctgg accattgtgg ttaatggcac acaggcatca tccgccagca gattcatacc
    10921 ggcgacagaa gccgtattca gccccatact ggcgagttgc gcgcgtgtca ggcagggaac
    10981 aatcccttgt tcactgtcgc ccgtattaaa tgtgacatca cgcgttgcca tataaccatt
    11041 attcaaatag atatcgacgc gatacgtccc tggcggtaat tcttgcccat tttcaaaacg
    11101 cgataaatcg gccacagcct ggggatcatc cgctaaaaag cgcggattaa aatagaggtc
    11161 ggcagatgac aaaggtgcct gtgcggcaaa agcacaggcg acaacgagtc ggacaaaaaa
    11221 accagccaaa cgatgcttac gaatatgcaa gcattgtgtg tttcgctggt aaagtcttaa
    11281 attcagatat gacattattc ctccggctta aaatcacccg gcagtcaatt ctttttattc
    11341 aggcgaaaaa ttccccctgc gttattccat tacgcccgtc attttggggg taagtgcgcc
    11401 ataatcattt attgttcggt aagtaatatt gcttcctgca tcagaaggca atttaaccgt
    11461 gctttcgccc attggaggca ccaatgcatt ttcaagaacc cgggttccgg cattcaactc
    11521 tgttaccgtc aggtaatagg gtgtcgggtt aatcagcgtc agagaattcg cgctacgacg
    11581 aaatcttaat ttttctgcgg cctgatcggg tggcaacgct aatttagccg ggcgatagta
    11641 cagtttaatg cggctgataa ttgcgagctg tagcgtattc tcagtcaatt ttgatttatc
    11701 cattgacgga atcgctttaa cgttcatcca gaataaactt tcccggtcct gtggcaattg
    11761 gttatttgtt gcatcaagaa tacgtaaggt attctctttt tttcccttca tcgcaaacag
    11821 aggaggcgtc acgataaaac gaccatcctt tacaccatcg gcattttcca cccatgattg
    11881 aattaaatag gtactatttt catcattatt tgtcacggca agttgcactt gtttttgccc
    11941 tgccggataa attacgcgag tcgcacctaa ggccactccc gcttcagcgc gtccggcaac
    12001 catcattgcc atgaacatca ggatacctgc cagcaagcag aatgttattt cctgcgattt
    12061 ccttacattg acgtttttat tactcactgt cctgttcctg ttatcacatt atctgctgaa
    12121 caattactga taggttaaag agaaccaggc ctgggcattg gcgatgccgc cagtaacccg
    12181 acgcccggta gcacgatatt tggcgatgaa atgtagcgaa gtagagcctg aataaagccg
    12241 tttccagttt gctggaggac gattaatcgg tacgaggttt ccttcatcat caaacaacgc
    12301 tacgccaata ttggtggcta tccctggccc ctctcccacg gaaagcacat ccggattttt
    12361 accatccgcg acaccgtgaa acgccacacc tacacgttca ctcaccaccg tactacattc
    12421 ccgtaaatga ataacaaaag gcaccggtgc gctatcttcc ccaaccgcat gaaaccggtt
    12481 actgctgatt tgccccatat tgaccgtcat ttgtttatca ccggcttcaa tccggcaagt
    12541 ttccgcaata atgacgccct gaaattgcat atttccgccg ggcaacgtgg tattccattt
    12601 atttccggcc agagcaaaca ttggcagcaa cgacgctaat agaaataatc tcttcctttt
    12661 catcgttatt tttatcgcac aagggtgggc atccctgccc gtaatgacgt ccctgaacct
    12721 gggtaggtta ttgatactga accttgaagg tcgcatccgc attagcagca cccggggttg
    12781 cggccccggt tgcaaaataa cgcgcctgga acggaatggt attggttccg ttattcaggg
    12841 ttgtttctga actaaatgtc gcaccatcca gcgtcagcgc agcacccgtt ctgtccagga
    12901 tctgcacacc aacgtttgtt gcgctacccg cagctgaact ctgcagagcc agaacgttgg
    12961 tatgacccgc atcaatcgcc gtacctaaaa aggcaacagc ggctttagat gcaacattag
    13021 tatcgcaatc attcagctga atgttaaaac cgacagcaga actggttgct ccttcctgtg
    13081 ccagcgatgc ggtacgaacc tgtcctaact gaacggtttg atcaacagag cctgcatcaa
    13141 ctgcgcaagc ggcgttaaca acttcccctt taaagtgaac ggtcccacca ttaaccgtcg
    13201 tggcagcggc cagagccgct gtagaactga gggacagagc cgacagaaca acgattgcca
    13261 gagttttaat tttcatgctg ctttcctttc aaaaaactat ttctaaatcg acatgggcag
    13321 tcgttctgta cactttgttt tgtcaacgag tttgactgcc aacactgcac agttttcccc
    13381 caaaagatga aacatttggg gccattttga ctcatagagg aaagcatcgc ggacaaactt
    13441 tttcagttta tttgttggct taatattc
//
LOCUS       DAPHKZ010000122        13351 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.122, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000122 DAPHKZ010000000
VERSION     DAPHKZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13351
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.122"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            28..1974
                     /gene="yegI"
                     /locus_tag="RH288_003682"
     CDS             28..1974
                     /gene="yegI"
                     /locus_tag="RH288_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YegI"
                     /protein_id="HDV4032696.1"
                     /translation="MKTNIKVFTSTGEMTTLGLELGKGGEGAVYDINEFVDSVAKIYH
                     TPPPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMI
                     YSPAHRRQRYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLI
                     DSDSFQINANGTLHLCEVGVSHFTPPELQTLSSFVGFERTENHDNFGLALLIFHVLFG
                     GRHPYSGVPLISDAGNALETDITHFRYAYASDNQRRGLKPPPRSIPLSMLPSDVEAMF
                     QQAFTESGVATGRPTAKAWVAALDSLRQQLKKCTVSAMHVYPGHLADCPWCALDNQGV
                     IYFIDLGEEVITTGGDFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRRE
                     YIILLEIALSALSLLLCGLQAEPRYIILVPVLAAIWIIGSLTSKAYKAEVQQRREAFN
                     RAKMDYDHLVRQIQQVGGLEGFIAKRTMLEKMKDEILGLPEEEKRALAALHDTARERQ
                     KQKFLEGFFIDVASIPGVGPARKAALRSFGIETAADVTRRGVKQVKGFGDHLTQAVID
                     WKASCERRFVFRPNEAITPADRQAVMAKMTAKRHRLESTLTVGATELQRFRLHAPART
                     MPLMEPLRQAAEKLAQAQADLSRC"
     gene            complement(1986..3338)
                     /gene="yegD"
                     /locus_tag="RH288_003683"
     CDS             complement(1986..3338)
                     /gene="yegD"
                     /locus_tag="RH288_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV4032697.1"
                     /translation="MFIGFDYGTANCSVAVMRDGKPQLLKMENDSTLLPSMLCAPTRE
                     AVSEWLYRHHDVPADDDETQALLRRAIRYNREEDIDVTAKSVQFGLSSLAQYIDDPEE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPEAITQAVIGRPINF
                     QGLGGDEANAQAQGILERAAKRAGFRDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGG
                     GTTDCSLLLMGPQWRSRLDREASLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPILPWWNAVAINDVPAQSDFYSSANGRLLNDLVRDAREPEKVALLQKVWRQRLS
                     YRLVRSAEECKIALSSVAETRASLPFISDELATLISQQGLESALSQPLARILEQVQLA
                     LDNAQEKPDVIYLTGGSARSPLIKKALAEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            3472..4329
                     /gene="alkA"
                     /locus_tag="RH288_003684"
     CDS             3472..4329
                     /gene="alkA"
                     /locus_tag="RH288_003684"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HDV4032698.1"
                     /translation="MYTLNWQPPYDWSWMLGFLAARAVSGVETVAEDYYARSLAVGEY
                     RGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGKLGAAR
                     PGLRLPGCIDAFEQGVRAILGQLVSVAMAAKLTAKVVQLYGERLDDFPEYICFPTPQR
                     LAAADPQALKALGMPLKRAEALIHLANAALEGSLPMTIPGDVEQAMKTLQTFPGIGRW
                     TANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEG
                     WQPDGTDEL"
     gene            complement(4368..7685)
                     /locus_tag="RH288_003685"
     CDS             complement(4368..7685)
                     /locus_tag="RH288_003685"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDV4032699.1"
                     /translation="MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLA
                     PLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAV
                     VGAVLLRKLLPWYNPLQNLADWLRLALGSAIVPPLLGGILVVLLTPGDDPLRAFLIWV
                     LSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTF
                     IIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLI
                     LLPANIMTMVMYAFRAERKHISESETRFRNAMEYSAIGMALVGTEGQWLQTNKALCQF
                     LGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALL
                     AVSLVRHTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWELKPN
                     VFSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRIT
                     VKDGIRHIRALANRVLNKEGEVERLLGINMDMTEVKQLNEALFQEKERLHITLDSIGE
                     AVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTS
                     RSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSA
                     SHDALTHLANRASFEKQLRMLLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALL
                     RELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGR
                     VHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGRGRVTVYEPQQAAAHSERAA
                     MSLDEQWRMIKENQLMMMAHGVASPRIPEARNLWLISLKLWSCEGEIIDEQKFRRSFS
                     DPALSHALDRRVFHEFFQLAAKAVASKGISIALPLSVAGLSSATLVNDLLEQLENSPL
                     PPRLLHLIIPAEAILDHAESVQKLRLAGCRIVLSQVGRDLQIFNSLKANMADYLLLDG
                     ELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGDVIA
                     DAQPLDLLVNSSYFAIN"
     gene            8003..8644
                     /gene="udk"
                     /locus_tag="RH288_003686"
     CDS             8003..8644
                     /gene="udk"
                     /locus_tag="RH288_003686"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDV4032700.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTR
                     MKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            8736..9317
                     /gene="dcd"
                     /locus_tag="RH288_003687"
     CDS             8736..9317
                     /gene="dcd"
                     /locus_tag="RH288_003687"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HDV4032701.1"
                     /translation="MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDESEAFYLHPGELALAVTLESVTLPAD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD"
     gene            9339..11192
                     /gene="asmA"
                     /locus_tag="RH288_003688"
     CDS             9339..11192
                     /gene="asmA"
                     /locus_tag="RH288_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HDV4032702.1"
                     /translation="MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSG
                     YQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLVRADNMRLDVALLPLLSHQLSVK
                     QVMLKGAVIQLTPQTEAVRSEDAPVAPRDNTLPDLSDDRGWSFDISSLKVADSVLVFQ
                     HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTISLNGTVDASDYPHDLTA
                     AIEQINWQLQGADLPKQGIQGQGSFQAQWQESHKRLSFNQISLTANDSTLSGQAQVTL
                     TEKPEWQLRLQFPQLNLDNLIPLNETANGENGNAQQGQSQSTLPRPVISSRIDEPAYQ
                     GLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGQVSLPGTLD
                     ATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQG
                     QAHVEMADTRMEGMNFQQMIQQAVERNGGDVKAAENFDNVTRLDRFTTDLTLKDGVVT
                     LNDMQGQSPMLALSGAGTLNLAEQTCDTQFDIRVIGGWNGENKLIEFLKETPVPLRVY
                     GKWQQLNYNLQVDQLLRKQLQDEAKRRLNDWVERNKDSRNGKDVKKLLEKM"
     gene            complement(11644..13227)
                     /locus_tag="RH288_003689"
     CDS             complement(11644..13227)
                     /locus_tag="RH288_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416567.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDV4032703.1"
                     /translation="MEWIADPSIWAGLITLIVIELVLGIDNLVFIAILAEKLPPKQRD
                     RARVTGLLLAMLMRLLLLASISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKAT
                     MELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAVGMVDHLLVMMAA
                     VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAI
                     GFSVMIEALNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVD
                     HGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEEEIRQLLERNQHT
                     RLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLVRQPLVFPETLLLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHR
                     VQKVQIIPLRKDGEMEYEV"
BASE COUNT         3217 a         3504 c         3520 g         3110 t
ORIGIN      
        1 atataatatt gctgcccttg aaacattatg aagacaaata taaaagtatt tacatcaaca
       61 ggtgaaatga ccactctcgg tcttgaactg ggcaaaggcg gtgaaggcgc ggtttatgat
      121 atcaatgagt ttgtcgatag cgtcgccaag atttatcaca cgccgccacc cgccttaaaa
      181 caggacaaac ttgcctttat ggctgcgaca gctgacgcgc aattgttgaa ttatgtcgcc
      241 tggccgcagg caacgcttca cggtggacga ggcggaaaag ttatcggttt tatgatgcca
      301 aaagtttctg gtaaagaacc gattcatatg atctatagcc cggcacatcg tcgtcaacgt
      361 taccctcatt gtgcgtggga ttttctactc tatgttgcgc gcaatattgc ttcatctttt
      421 gctacggttc acgagcacgg gcacgtcgtg ggtgacgtaa accagaacag ttttatggta
      481 ggtcgcgaca gcaaagtggt actgattgat agcgactcct ttcagattaa cgccaatggc
      541 acactgcatt tatgcgaagt cggcgtgtcg cattttacgc cgccagagct acaaaccttg
      601 tcgtcatttg tcggctttga acgcacagaa aatcacgata attttggcct tgcgttgctg
      661 atttttcacg tcttgtttgg tggccggcat ccttattctg gtgtgccgct tatctctgat
      721 gcgggtaatg cgctggagac ggatattacc catttccgtt atgcctacgc gtcagataat
      781 cagcgacgtg gtttaaaacc gccgccacga tcgattccgc tatcgatgtt accgagtgat
      841 gttgaagcca tgtttcagca ggcattcacg gaaagtggcg tggcaaccgg gcgtccgacg
      901 gctaaagcgt gggtagcggc acttgattct ctgcgccaac agttaaagaa atgtaccgtt
      961 tcggcaatgc atgtttatcc cggtcatttg gctgactgcc catggtgtgc gctggataat
     1021 caaggtgtta tctattttat tgatctcggc gaagaggtca ttaccaccgg cggggatttt
     1081 gtgctggcaa aagtctgggc gatggtgatg gcgtcagtag caccgccagc attgcaactg
     1141 ccattacccg atcatttcca accgactggc aggccgcttc ctttaggcct gttacggcgc
     1201 gaatacatca ttctgcttga gatcgcactg tcagcattat cgctgctgct ttgcggcctt
     1261 caggcagaac cgcgttatat tattttggtt cctgtgctgg cggctatctg gattattggc
     1321 agtctgacaa gcaaagcgta caaagcagaa gttcagcaac gccgtgaggc atttaatcgt
     1381 gcgaaaatgg actatgacca tttagtccgc cagatccagc aggtaggcgg cctggaaggt
     1441 tttatcgcca aacggacgat gctcgaaaaa atgaaggacg aaattctcgg gttaccggaa
     1501 gaagagaaac gcgctctggc agcacttcat gacactgcaa gggaacggca gaagcagaag
     1561 tttctggagg gattttttat tgatgttgcc tctattcccg gcgttggccc tgcgcgtaaa
     1621 gcggcgttac ggtcttttgg tattgaaaca gccgcagatg ttacccgtcg tggcgttaag
     1681 caagttaaag ggtttggcga ccatctgacc caggcggtta tcgactggaa agcgagctgt
     1741 gaacgccgtt ttgtgttcag gccgaatgaa gcgataacgc cagcagacag acaagcggta
     1801 atggcgaaaa tgaccgccaa acgacatcgg ctggaatcga cgttgactgt cggcgcgaca
     1861 gagttgcagc gattccgcct tcatgctcca gcacggacca tgccgttgat ggaaccttta
     1921 cgtcaggcgg cagaaaaact ggctcaggcg caggcagatt taagccgctg ctgagccatt
     1981 ttcttttaac gaaacaccac ttccgcccag cgtgccagcc cggcggtgac ggagccaaag
     2041 tcatcgccgc ctgcaatcgg aattcccggc aactgttctg ccagcgcttt tttaatcagc
     2101 ggcgaacggg cgctaccgcc ggtcaggtag ataacgtccg gtttttcctg ggcgttatcc
     2161 agggccagtt gcacctgttc cagaatccgc gccagtggct ggctgagggc gctttccagc
     2221 ccttgctggc taatcagcgt agccagttca tcgctgataa acggcagtga ggcgcgggtt
     2281 tccgctacgc ttgaaagagc aattttgcac tcttctgcgc tacgcaccag gcgatagctt
     2341 aaacgctgac gccagacttt ctgtagcagg gccacttttt ccggttcgcg ggcatcgcgt
     2401 accagatcgt taagcagacg accgttggca ctactgtaga aatcactctg cgcaggtacg
     2461 tcgttgatgg caaccgcatt ccaccacggc agaatcggca gggcgatgcc tttttcggtt
     2521 tcgccaccca tgcccagtaa cggcatcagg tttttaaacg ccagtgcgat gtccagatcg
     2581 ttaccgccaa tacggcaacc actgtgaccc agcaggctgg cttcacgatc gagacgcgaa
     2641 cgccactgcg gccccatcag cagcaatgaa cagtcagtcg taccaccgcc gatatccacc
     2701 accagcaccc gtttttcttc ctgcaaggtg gcttcgtaat ccagcccagc cgcgaccggc
     2761 tcgtactgga ataccacgtc cctgaatccg gcacgcttcg ccgcgcgttc cagaatccct
     2821 tgcgcctggg cgtttgcttc atcgccgccc agcccctgga agttgatcgg gcgaccaatc
     2881 accgcctgag taatcgcttc tggcagctgc gcctgcgcct gctggcgaat gtgcaacatc
     2941 attgcgcaga ccagatcctc aaacagcgct acctgctgcg gttttaagcc gctggcaccg
     3001 aggaacgatt ttggtgattt cacaaaccac acttcttctg gatcatcaat gtactgtgcc
     3061 agtgaggaaa gaccgaactg cacgcttttc gccgtaacat cgatatcttc ttcgcggtta
     3121 taacgaatcg cccgacgtaa cagcgcctgc gtttcatcgt cgtctgccgg aacatcatga
     3181 tggcggtaca gccattcact tactgcttca cgcgttggcg cgcaaagcat tgaaggcagc
     3241 agcgtgctgt cgttttccat tttcagtaat tgcggtttac cgtcacgcat gaccgccact
     3301 gaacagtttg ctgtaccgta atcaaaacca ataaacacga attaatcccc atgccggtga
     3361 agaaggggcg tgactttagc gaaatgttgc cgtcgcgaca accggaatat gaaagcaaag
     3421 cgtagcgtct gaataacgtt tatgctgaaa gcggatgaat aaggagatgc gatgtatacc
     3481 ctgaactggc agccgccgta tgactggtcg tggatgttgg gatttctcgc cgcccgtgcg
     3541 gtgagtggtg tggaaacggt cgctgaggat tattatgccc gtagtctggc ggtgggcgaa
     3601 tatcgcggcg tggtgactgc tattccggat atagcccgcc atactctgca cataaattta
     3661 agtgcaggtt tagaacccgt tgccgctgag tgtctggcga aaatgagccg cctgtttgat
     3721 ctgcaatgta acccgcagat tgttaacggt gcgttgggca agttaggcgc ggcgcggccc
     3781 ggattgcgtt tacccggctg tattgatgct tttgagcagg gtgtgcgggc gattttaggc
     3841 caactggtga gcgtggcgat ggcggcaaaa ttgactgcca aagttgtaca gctttatggc
     3901 gaacggctgg atgattttcc ggagtatatc tgcttcccca cgcctcagcg gctggcagca
     3961 gccgacccgc aggcattaaa agcgttaggc atgccgttga aacgggcaga ggcactgatt
     4021 catctggcaa atgcggcgct ggagggcagc ttaccaatga caattccggg cgatgtggag
     4081 caggcgatga aaacgctgca aacttttccg ggtatcgggc gctggacggc gaattatttc
     4141 gctttgcgtg gctggcaggc gaaagatgtt tttctgccgg atgattatct gattaaacag
     4201 cgatttccgg ggatgacacc ggcacaaatc cgccgttatg ccgagcgctg gaagccctgg
     4261 cgttcttatg cgctgttgca tatctggtat acggaaggct ggcaaccaga cggaacggac
     4321 gaattgtagg cctgatacgt cgcatcaggc aatgggcaaa cgctccctca gttaatcgcg
     4381 aaataactgc tattcaccag caaatccagc ggttgggcat cggcaatcac atcaccataa
     4441 atcagatcga cgccgatgcc agaaagcgta tccatcacta agggtaaaac gactggcccg
     4501 gcgatggttt tcatcccgag tcgctgagcg tgcccctgaa taatcgtaat cagcatctca
     4561 tccatcaaat taccctgcac gttggcgcat aactcaccat caagtagcag gtaatctgcc
     4621 atattcgctt tcagcgagtt gaagatttgc agatcgcggc ccacctggct gagcactatc
     4681 cgacatcccg ccagccgcag tttttgcacg ctttctgcgt gatctaaaat cgcttcagcc
     4741 ggaataatca ggtgtaataa ccgtggtggt agagggctat tttccagctg ctcaagcaga
     4801 tcattcacca gcgtggcgct actcaaaccg gcaacggaaa gggggagggc gatgcttatg
     4861 cctttactgg caaccgcttt tgcggccagc tggaaaaatt cgtggaatac ccgtcggtca
     4921 agagcatggc taagtgccgg atcgctgaag ctacgacgaa atttttgttc atcaataatc
     4981 tcgccttcgc aactccagag tttaagcgaa atcagccaca aattacgcgc ttccgggatc
     5041 cgcggcgaag cgacaccgtg ggccatcatc atcaactgat tctctttaat catccgccac
     5101 tgttcatcaa gcgacatcgc cgcccgttcg ctatgtgcgg cagcttgctg tggttcgtaa
     5161 accgtcaccc ggccccgtcc accatttttg gaggcataac aggcgatatc agcctgcgac
     5221 atcacttctg ccgcctgatg attgttgtca tcaatcaagg taatcccggc actggcacct
     5281 acccgatgca cacggccttc ccatataaag tgatagtcat tcacggcact gataatgcgt
     5341 gtagcgataa aacgcgcgct ttcaacatta cagtctggta gcagcagacc aaattcatcc
     5401 ccaccgagtc gcgccagcac gtcgctggaa cgcagcatac tcagcatcaa cgacgccagt
     5461 tcgcgcagca aagcgtcgcc cgccgcatgc ccggcgctgt cattcaccgc tttaaagcga
     5521 tcaagatcga taaacaccag ggcatgtcgc tgatgtgtac tgtttaccgt ttgcagcagc
     5581 atacgcagtt gcttctcaaa actggcgcga ttggcgagat gcgtcagtgc atcatgggag
     5641 gcgctgtagc tcagctggcg cagcattttg cgtgattcgg tgacgtcctg aatcaccaga
     5701 accgaaccaa tattgctgcc gtccagagta cttaacggcg taatactgta atgcacgtcg
     5761 taactgccgc cgctccgaca gtgcaacacc acatcttgtt cgattgcgga acgtgaggtg
     5821 tcggcactgt aaatgttctc cattaatggt ccgttgtcgc caaaagtaat atgcaacacc
     5881 gtcaggagcg gaacacctaa cgcttcttcc tgcgtccagc cgctcatctt ctccgccact
     5941 ggattcataa aggtaatttt catcgccata tcaatacaga ccacggcttc accgatggaa
     6001 tcaagcgtaa tgtgcaggcg ctctttttcc tgaaacaatg cctcgttaag ctgtttcact
     6061 tcggtcatat ccatattgat gccgaggaga cgttcgactt cgccttcttt attcagtacc
     6121 cggttggcga gggcgcggat atggcgaata ccgtctttta cggtaatgcg aaattccagt
     6181 ttaaagggcg agcgtgattg caacgaatca cgaatcactt tttcggcatg ctggcgatct
     6241 tccggcagca cgcactcgta ccacacctgc cagttcggtt tgatatgtgg aggaatttca
     6301 tacagctcga acatccgctt atcccagcta aaaacattcg gcttcaactc ccactcccag
     6361 atgccaatcc cgcccgcttc gttagccagc gtgatgcgct ccatcagttg ctgattgacc
     6421 tgttcggtgc gttttagctc gttaatgtct tcaatctgag cgataaaata gagcggcgtg
     6481 ccatccgtgt ggcgcaccag tgagacggca agcaacgccc agacaacatc gccattgcgg
     6541 ttgtagtagc gtttttccat tgaataggtg tttatttcac cgcttatcag cttttcaacc
     6601 tgttggagat ctttattgag atcctccggc caggtcagtt gctgaaaggt gagtccgcgc
     6661 agctcttcct gactgtaccc gagaaactgg cagagcgctt tgttggtttg cagccattgt
     6721 ccctcggtgc ccactaacgc cataccgata gcggaatatt ccatcgcgtt ccgaaagcgg
     6781 gtttcgcttt cggaaatgtg tttgcgttcc gcacgaaagg catacatcac catcgtcatg
     6841 atgttggcgg gcagcaggat cagcaaaaac ggtagccacg gcatatggct catcaggtac
     6901 gtacgcggcg tagcaagcag ggagggatcc gcggccatca tcagcgacac catcatcacc
     6961 gtggtaagga agatcaaaaa ggcttccatt cgtggcaggc gcacggcgct ccacatcaac
     7021 agcacaataa tgaaagtaaa aggccacggc agatacagca tcgaaagcca gcttaacgtc
     7081 agtgtgatgg ctaacgtgag cagcgactca aaaagcaacc gtgggttgcg atggcgcagc
     7141 agatagtgtg gtttaaataa caatcccagc ggcaccagtg ccagagcgcc gatggattct
     7201 gacagtaccc atatcaaaaa tgccctgaga ggatcgtctc ctggcgtcag caggacaacc
     7261 agaatacccc ccaacagagg cggaacaatg gcgctgccga gtgccagacg cagccagtca
     7321 gccagatttt gcaaggggtt ataccacggc agcaatttac gtagcagcac tgccccgacc
     7381 acggcttcaa caatattgat ggtcgtccag gtcatgttca gcgagctggt ggaaaaaagc
     7441 aggatggatg cggcgatatt tcccagcgaa cagctcagcg caattcccgg ccacatgcgc
     7501 ccggcatggc gataaaacgc caccatcatg atggacgtcg ggaaccacag tggggcgagt
     7561 tgggtgccaa actgcgaaag ctcaagcgag aaaagggtga agataaacga gactaaacct
     7621 aaactgacca ggtgaagcag cgggtggggc agggcaatta atacatgctg tgattgtttg
     7681 ctcattaccg ctttatccgc aaggccaggt cgccagtatt cgtttctgtg tttatgctag
     7741 tacaaaagtt ttacatttta tatgcgaatt gctcataaag tgacgtaaag gcggataatt
     7801 tgcgcaaccg cgtataacat tttttacctt acataaaact gatcaacgta atttgccacc
     7861 gggaattctt cgtcaacaat taactctgag cgcgcggcaa cgctattcga ctggtatcag
     7921 gcggatgaaa tccctataat tgccgcgttt ggcgcttcgt cgcccccttc ctaacatcca
     7981 ggttaatcag gtcgctaaat atatgactga tcagtctcat cagtgcgtca ttatcggtat
     8041 cgctggcgca tcggcttccg gcaagagtct tattgccagt accctttatc gtgaattacg
     8101 tgagcaagtc ggtgatgaac acatcggcgt aattcccgaa gactgctatt acaaagatca
     8161 aagccatctg tcgatggaag aacgcgttaa gaccaactac gaccatccca gcgcgatgga
     8221 tcacagtctg ctgcttgagc atttacaagc gttgaaacgc ggctcggcaa ttgacctgcc
     8281 ggtttacagc tatgttgaac atacgcgtat gaaagaaacg gtgacggttg agccgaagaa
     8341 ggtcatcatt ctcgaaggca ttttgttgct gacggatgcg cgtttgcgtg acgaacttaa
     8401 cttctccatt ttcgttgata ccccgctgga tatctgcctg atgcgccgca tcaagcgtga
     8461 cgttaacgag cgtgggcgtt caatggattc agtgatggcg caatatcaaa aaaccgtgcg
     8521 cccgatgttc ctgcaattca ttgagccttc taaacaatat gcggacatta tcgtgccgcg
     8581 cggcgggaaa aaccgcatcg cgatcgatat attgaaagcg aaaataagtc agttctttga
     8641 ataagcttga taaattgtgt accgttcagt gataacctgg tatgcccttg acgtaattgg
     8701 cgttaaggga gtgatgcgcg aaaggagaaa atgccatgcg tctgtgtgac cgagatattg
     8761 aagcctggct tgatgaaggc cgtttgtcga tcaacccacg tccgccagtg gagcgtatta
     8821 acggcgcgac ggtggatgtg cgcctgggca ataaatttcg taccttccgt ggtcacacgg
     8881 cagcgtttat cgatctgagc ggtcccaaag atgaagtgag cgccgcgctt gaccgcgtga
     8941 tgagcgatga gatcgttctc gatgaaagcg aggcgttcta tcttcaccca ggagagttgg
     9001 cgctggcggt gacgctggag tcggtgacgc tgccagccga tctggtgggc tggctggacg
     9061 ggcgttcctc cttggcgcgt ctggggctga tggtgcacgt caccgcgcac cgcatcgatc
     9121 cgggctggtc tggctgcatt gtgctggagt tctacaactc cggtaagctg ccgctggcgc
     9181 tgcgtccggg catgttaatt ggtgcgctga gctttgagcc gctttccggc ccggcggcgc
     9241 gaccttacaa ccgccgcgaa gatgcgaaat atcgcaacca gcagggcgcg gtagccagcc
     9301 gaatcgataa agactaattc aggcccattg aggataccat gagacgattt ctgacgacgc
     9361 tgatgatact cctggtcgtg ctggtggccg ggttatctgc gttagtgttg ctggtgaatc
     9421 cgaatgattt ccgcgactat atggtcaagc aagttgctgc acgtagcggt tatcaattgc
     9481 agctcgacgg gccactgcgt tggcacgtct ggccgcagct tagtatcctc tccgggcgaa
     9541 tgtctctcac cgcccagggc gcgagccagc cactggttcg cgccgacaac atgcgcctgg
     9601 acgtggcgct tttaccacta ctgagtcatc aactgagcgt taagcaggtg atgctaaaag
     9661 gggcagtgat ccaactgacg ccgcagacgg aagcggtgcg cagtgaagac gctccggttg
     9721 caccgcgcga caataccttg ccggatctgt cagacgatcg cggatggtcg tttgatatat
     9781 ccagtcttaa ggtggcggac agcgttctgg tgttccagca tgaagatgac gagcaggtga
     9841 caatccgcaa tattcgcctg caaatggaac aagatcccca acatcgtggc tcatttgagt
     9901 tctccgggcg ggttaatcgc gatcagcgcg atctcacgat atcccttaac ggtacagtag
     9961 atgcttctga ttatccgcat gatttaacgg cggctattga acaaattaac tggcagttgc
    10021 agggtgccga tttaccaaaa caaggtattc aggggcaggg gagtttccag gcccagtggc
    10081 aggagtcaca taaacgcctt tcatttaacc aaatcagctt gaccgccaat gacagtacgc
    10141 tgagcgggca agcacaggtc acgctgacag agaaaccgga atggcagctg agactgcaat
    10201 tcccgcaact gaatcttgac aacctcatcc cgcttaatga aacagcgaat ggtgaaaacg
    10261 gtaacgcgca gcaggggcag agccaatcaa cgttgccgcg cccggttatt tcttcgcgta
    10321 ttgatgaacc ggcctatcag ggactgcaag gctttacggc tgatattttg ttgcaggcca
    10381 gtaacgtgcg ctggcgcgga atgaatttta cagatgttgc cacgcaaatg accaacaagt
    10441 cgggtttgct ggaaattact caactgcagg gcaaacttaa cggtggacag gtttcactgc
    10501 cgggcacgct ggacgcgaca tcaataaatc cgcggataaa cttccagcca cggctggaaa
    10561 atgttgagat tggtaccatt ctgaaggcgt ttaactatcc gatttcgttg accggaaaaa
    10621 tgtcactggc tggtgatttc tccggtgctg acatagatgc cgacgcattc cgccacaact
    10681 ggcaaggaca ggcacatgtc gaaatggccg atacgcgcat ggaagggatg aacttccagc
    10741 agatgattca gcaagcggta gaacgtaatg gtggtgatgt gaaggccgct gaaaacttcg
    10801 ataacgtgac gcgtcttgac cgctttacca ccgatttgac gttgaaggat ggcgtcgtga
    10861 cgttaaacga catgcaaggt caatcgccca tgctggcgct ttccggggct ggtacgttga
    10921 atctggcgga gcaaacctgc gacacccagt ttgatattcg tgtgattggc ggctggaacg
    10981 gtgaaaataa actgattgaa ttcctcaaag aaacgccagt accgctgcgg gtttatggca
    11041 aatggcagca actcaattac aacctgcaag tggaccagtt gctgcgcaaa cagttacagg
    11101 acgaagcgaa acgtcgcctg aatgactggg tcgagcggaa taaagattcc cgcaatggca
    11161 aagatgtgaa gaagttgctg gagaagatgt aggttaccag gtgacctgtc ctgtaggcct
    11221 gataagacgc gtaaagcgtc gcatcaggcg ttcgtggcgg caccattata ttctgaatat
    11281 gtaagatcga aggctgttcc gttcacttga tgttcctcgc tactatggaa cgctcaagcc
    11341 ggtgaacgtg ccagggtggc tcaatcgcca ccaccctggc aacccgggct cccggcggta
    11401 aatcgccgct ggcgcggttc cctcatctta ttcctttcgg ctatcgggta cgggcgcgag
    11461 gtaacatccc tgtaaaacgc gccctcagcc cacatccatg tgggctgccc cggcctacag
    11521 gaaacgattc ggcgatttac agccggaccc acccccccgc tgtaatgtcc atgtaccaca
    11581 gacaacgctt cattgctgaa gttataaggc gttacgcagc atcgggtaaa atgaccgata
    11641 ccatcacacc tcgtactcca tctcgccatc cttacgcagc ggtataatct gcaccttctg
    11701 cacgcgatgg ctttccacct gcaacgtttt aagcaaataa tcccctacct gcacttcttc
    11761 gccaggtttt ggaatacgct gcaaatactc catcaacagc ccggcaatgg tgtgatattc
    11821 acgtttttca tccagcggca gcggcacata ttgcaccaga tcctccagcg gcatatgacc
    11881 attcgccgtc caggaaccgt ccgcattctt ctgaatatca tggcgggcgt cgatctcttc
    11941 cacttcgttc ggtaagttac cggcaatggt ttcagtgacg tcacttaatg tcacaatccc
    12001 ttccaccgag ccaaactcat ccaccacaaa agcaaagtgc gtgcgggcat tacggaactg
    12061 ctccagagcc ggtaacaaca gcaaggtttc cgggaacacc agcggctggc gaaccagtac
    12121 ccgcaggttg agcggttcgc cacgcagtga ctgttgtagc aggtcgataa cgtgaacgac
    12181 accgagcaaa tcttccgcgt cgtcaccgtc agtaaccacc agtcgcgtgt gctgatttcg
    12241 ctccagcaac tgccggattt cttcttccgg cgcgttgaga tcgatatgct caatatcgtg
    12301 gcgcgaggtc atgatgctgc tgacagtgcg ctggttaaga ttaagtaccc gctcaatcat
    12361 tcgtcgttcc tgcggattaa agatctgctg gttaccatga tccaccagca tggacgcggt
    12421 ttcggcgtcc agttccgcat cttctttttg cccgctaagc agacgcatta ccgcttcggt
    12481 agtacgctgg cgcagtgtct ggttagcgga aagaaaacgt cgccggttaa agatagccaa
    12541 ctgattgagc gcctcgatca tcaccgagaa accaatggca gcgtacaggt agcctttcgg
    12601 aatgacgaag ccgaaacctt ccgccaccag gctaaagcca atcatcaaca ggaagcttaa
    12661 gcagagaata acgatcgtcg ggtgactgtt aacaaattgc gttaacggct tgctggccat
    12721 caacatcagg ctgatagcga taaccacggc ggccatcatg accagtaaat ggtcgaccat
    12781 cccgacggcg gtaatcactg agtcgagtga gaagatggcg tccagtacca caatttgcgt
    12841 caccacgccc cagaacttcg cacctttgcg ttgtgtgggg ttattgctgt ctttcccctc
    12901 cagacgttcg ttcaactcca tcgtggcttt gaacaacagg aagaaaccac caaacagcat
    12961 gattaagtcg cgggcgctaa aggtaaacga gcggaagctg aacagcggtt gagtcagggt
    13021 gaccagccag gagattgacg ccagcagtaa caggcgcatt aacatcgcca gcaacagccc
    13081 ggtaacccgt gcgcggtcgc gctgcttcgg cggtagtttt tcggcgagga tggcaataaa
    13141 gaccaggtta tcaatgccga ggaccagttc gatcacaatc agcgtgatta acccggccca
    13201 gatagacgga tcggcaatcc attccatagt aagtacaaaa cctattcgtt gtatgacaaa
    13261 tgtcacaatt cgatcatgga taaatcgggg caaaaatgca atgttgcagc actatttatc
    13321 tcatattatt tgagggtaat aacctcacat t
//
LOCUS       DAPHKZ010000123        13215 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.123, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000123 DAPHKZ010000000
VERSION     DAPHKZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13215
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.123"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1765
                     /locus_tag="RH288_003690"
     CDS             <1..1765
                     /locus_tag="RH288_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV4032704.1"
                     /translation="GALQAANEAATKGFDDQTRRLKENMGTLETWADRTARAFKSMWD
                     AVLDIGRPDTAQEMLIKAEAAFKKADDIWNLRKDDYFVNDEARARYWDDREKARLALE
                     AARKKSEQQTQQDKNAQQQSDTEASRLKYTEEAQKAYERLQTPLEKYTARQEELNKAL
                     KDGKILQADYNTLMAAAKKDYEATLKKPKQSGVKVSAGDRQEDSAHAALLMLQTELRT
                     LEKHAGANEKISQQRRDLWKAESQFAVLEEAAQRRQLSAQEKSLLAHKDETLEYKRQL
                     AALGDKVTYQEHLNALAQQADKFAQQQRAKRAAIEAKNRGLTDRQAAREATEQRLKEQ
                     YGDNSLALNNVMSEQKKTWAAEDQLRGSWMAGLRSGWSEWEESATDSMSQVKSAATQT
                     FDGIAQNMAAMLTGSEQNWRSFTRSVLSMMTEILLKQAMVGIVGSIGSAIGGAVGGGA
                     SASGGTAIQAAAAKFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRL
                     MRGYATGGYVGTPGSMADSRSQASGKFEQNNHVVINNDGTNGQIGPQALKAVYDVARK
                     AAMDVVTGQMRDGGLFSGGGR"
     gene            1762..2091
                     /locus_tag="RH288_003691"
     CDS             1762..2091
                     /locus_tag="RH288_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4032705.1"
                     /translation="MKTFRWKVKPGMDVASAPSVRKVRFGDGYSQRAPAGLNADLKTY
                     SVTLSVPRWEATALESFLAEHGGWKSFLWTPPYEWRQIKVTCAKWSSRVSMLRVEFSA
                     EFEQVVN"
     gene            2091..2789
                     /locus_tag="RH288_003692"
     CDS             2091..2789
                     /locus_tag="RH288_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDV4032706.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDLQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            2795..3538
                     /locus_tag="RH288_003693"
     CDS             2795..3538
                     /locus_tag="RH288_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4032707.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVVRAPEGESYFPCVNISGEPE
                     EYFRMAPEDWLQAEMQGEIVALVHSHPGGLPRLSEADRRMQVQSDLPWWLVCRGTIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRHGQNLYLDNLEAT
                     GLYQVPLSSAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHREWHASAFTGICNDLAAASTFV"
     gene            3475..4077
                     /locus_tag="RH288_003694"
     CDS             3475..4077
                     /locus_tag="RH288_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HDV4032708.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALATQLPAFRQKLSD
                     GWYQVRIAGRDTGETELSARLNEPLANSAVIHIVPRLAGAKSGGVFQAVLGAAVMAVA
                     IWMPGVGIMASNLLFSLGASMTLGGVAQMLAPKPKTPRTQTTDNGKQNTYFSSLDNMV
                     AQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            4138..7617
                     /locus_tag="RH288_003695"
     CDS             4138..7617
                     /locus_tag="RH288_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HDV4032709.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVGNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKAWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGSGNPVSVEVQSVTDGVKVKVSRVPEGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGEQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFMLRLTVAADDGSERLVSTARTTETTYRFRQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAVPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRITDIRQVETTARYLGTALYWIAASINIKPGHDYYFYVRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSKVLLAADRIAMVNPANGNTKPMFVGQGDQIFMNDVFLERLTAPTITSGGNP
                     PAFSLTPDGKLTAKNADISGSVNANSGTLNNVTINENCQIKGKLSANQIEGDIVKTVG
                     KAFPRDSRAPERWPSGTITVRIYDDQPFDRQIVIPAVAFCGAKHERENNDIYSSCRLI
                     VKKNGAEIYNRTALDNTLIYSGVIDMPAGHGHMTLEFSVSAWLVNDWYPTASISDLLV
                     VVMKKATAGISIS"
     gene            7685..8284
                     /locus_tag="RH288_003696"
     CDS             7685..8284
                     /locus_tag="RH288_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HDV4032710.1"
                     /translation="MRKVCAAILSAAICLAVSGAPAWASEQQATLSAGYLHARTNAPG
                     SDDLNGINVKYRYEFTDTLGLITSFSYANAEDEQKTHYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGMAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAVDVAYEGSGSGDWRTNSFIVGVGYKF"
     gene            8349..11699
                     /locus_tag="RH288_003697"
     CDS             8349..11699
                     /locus_tag="RH288_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415890.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HDV4032711.1"
                     /translation="MAVKISGVLKDGTGKPVQNCTIQLKAKRNSTTVVVNTLASENPD
                     EAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYEDSRPGTLNDFLGAMTEDDARPEA
                     LRRFELMVEEVARNASAVAQNTAAAKKSAGDAGTSAREAATHATDAAGSARAASTSAG
                     QAATSAQSASSSAGTASTKATEASKSAAAAESSKSAAATSAGAAKTSETNAAASQKSA
                     ATSASAATTKASEAATSARDAAASKEAAKSSETNASSSASSAASSATAAGNSAKAAKT
                     SETNARSSETAAGQSASAAAGSKTAAASSASAASTSAGQASASATAAGKSAESAASSA
                     STATTKAGEATEQASAAARSASAAKTSETNAKASETSAESSKTAAASSASSAASSASS
                     ASASKDEATRQASAAKGSATTASTKATEAAGSATAAAQSKSTAESAATRAETAAKRAE
                     DIASAVALEDASTTKKGIVQLSSATNSTSETLAATPKAVKSAYDNAEKRLQKDQNGAD
                     IPDKGRFLNNINAVSKTDFADKRGMRYVRVNAPAGATSGKYYPVVVMRSAGSVSELAS
                     RVIITTAPRTAGDPMNNCEFNGFVMPGGWTDRGRYAYGMFWQYQNNERAIHSIMMSNK
                     GDDLRSVFYVDGAAFPVFAFIEDGLSISAPGADLVVNDTTYKFGATNPATECIAADVI
                     LDFKSGRGFYESHSLIVNDNLSCKKLFATDEIVARGGNQIRMIGGEYGALWRNDGAKT
                     YLLLTNQGDVYGGWNTLRPFAIDNATGELVIGTKLSASLNGNALTATKLQTPRLVSGV
                     EFDGSKDITLTAAHVAAFARRATDTYADADGGVPWNAESGAYNVTRSGNSYILVNFYT
                     GVGSCRTLQMKAHYRNGGLFYRSSRDGYGFEEDWAEVYTSKNLPPESYPVGAPIPWPS
                     DTVPSGYALMQGQTFDKSAYPKLAAAYPSGVIPDMRGWTIKGKPASGRAVLSQEQDGI
                     KSHTHSASASSTDLGTKTTSSFDYGTKSTNNTGAHTHSVSGTAASAGAHTHSITFVSG
                     GTKGAPGSGSPDYSKYSVNTSSAGAHTHSVSGTAASAGAHAHTVGIGAHTHSVAIGSH
                     GHTITVNAAGNAENTVKNIAFNYIVRLA"
     gene            11699..12274
                     /locus_tag="RH288_003698"
     CDS             11699..12274
                     /locus_tag="RH288_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV4032712.1"
                     /translation="MAFRMSEQPRTIKIYNLLAGTNEFIGEGDAYIPPHTGLPANSTD
                     IAPPDIPAGFVAVFNSDESSWHLVEDHRGKTVYDVASGDALFISELGPLPENVTWLSP
                     EGEFQKWNGTAWVKDTEAEKLFRIREAEETKNNLMQVASEHIAPLQDAADLEIATEEE
                     ISLLEAWKKYRVLLNRVDTSTAQDIEWPALP"
     gene            complement(12372..12962)
                     /locus_tag="RH288_003699"
     CDS             complement(12372..12962)
                     /locus_tag="RH288_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDV4032713.1"
                     /translation="MSRIFAYCRISTLDQTTENQRREIESAGFKIKPQQIIEEHISGS
                     AATSERPGFNRLLARLKCGDQLIVTKLDRLGCNAMDIRKTVEQLTETGIRVHCLALGG
                     IDLTSPTGKMMMQVISAVAEFERDLLLERTHSGIVRARGAGKRFGRPPVLNEEQKQAV
                     FERIKSGVSISAIAREFKTSRQTILRAKAKLQTPDI"
BASE COUNT         3221 a         3200 c         3960 g         2834 t
ORIGIN      
        1 cggggcattg caggcggcga acgaggccgc aacgaaaggg tttgatgacc agacccgccg
       61 cctgaaagag aacatgggca cgctggagac ctgggcagac aggacagcgc gggcattcaa
      121 atccatgtgg gatgcggtgc tggatattgg tcgtcctgat accgcgcagg agatgctgat
      181 taaggcagag gctgcattta agaaagcaga cgacatctgg aatctgcgca aggatgatta
      241 ttttgttaac gatgaagcgc gggcgcgtta ctgggatgat cgtgaaaagg cccgtcttgc
      301 gcttgaagca gcccgaaaga agtctgagca gcagactcaa caggacaaaa atgcgcagca
      361 gcagagcgat accgaagcgt cacggctgaa atataccgaa gaggcgcaga aggcttacga
      421 acggctgcag acgccgctgg agaaatatac cgcccgtcag gaagaactga acaaggcact
      481 gaaagacggg aaaatcctgc aggcggatta caacacgctg atggcggcgg cgaaaaagga
      541 ttatgaagcg acgctgaaaa agccgaaaca gtccggcgtg aaggtgtctg cgggcgatcg
      601 tcaggaagac agtgctcatg ctgccctgct gatgcttcag acagaactcc ggacgctgga
      661 gaagcatgcc ggagcgaatg agaaaatcag ccagcagcgc cgggatttgt ggaaggcaga
      721 aagtcagttc gcggtactgg aggaggcggc acaacgtcgc cagctgtccg cacaggagaa
      781 atccctgctg gcgcataaag atgagacgct ggagtacaaa cgccagctgg ctgcacttgg
      841 cgacaaggtt acgtatcagg agcacctgaa tgcgctggcg cagcaggcgg ataagttcgc
      901 acagcaacaa cgggcaaaac gggcagccat tgaggcgaaa aaccgggggc ttactgaccg
      961 gcaggcagcg cgggaagcca cagaacagcg cctgaaggaa cagtatggcg ataattcgct
     1021 ggcgctgaat aacgtcatgt cagagcagaa aaagacctgg gcggctgaag accagcttcg
     1081 cgggagctgg atggcaggcc tcaggtccgg ctggagtgag tgggaagaga gcgccacgga
     1141 cagtatgtcg caggttaaaa gtgcagccac gcagaccttt gatggtattg cgcagaatat
     1201 ggcggcgatg ctgaccggca gtgaacagaa ctggcgcagc ttcacccgct ccgtgctgtc
     1261 catgatgaca gaaattctgc ttaagcaggc aatggtgggg attgtcggga gtatcggcag
     1321 cgccattggc ggggctgttg gtggcggcgc atcagcgtca ggcggtacag ccattcaggc
     1381 agctgcggcg aaattccatt ttgcgaccgg aggatttacg ggaaccggcg gcaaatatga
     1441 gccagcgggg attgttcacc gtggtgaatt tgtcttcact aaggaggcaa ccagccggat
     1501 tggcgtgggg aatctctacc ggctgatgcg cggctatgcc accggcggtt atgtcggtac
     1561 accgggcagc atggcggaca gccgctcgca ggcgtccggg aagtttgagc agaataacca
     1621 tgtggtgatt aacaacgacg gcacgaacgg tcagataggg ccacaggcgc tgaaggcggt
     1681 ttatgacgta gcccgtaagg cggcaatgga tgttgtgacc gggcagatgc gcgatggtgg
     1741 tctgttctcc ggaggtggac gatgaaaacc ttccgctgga aagtgaaacc cggtatggat
     1801 gtggcttcgg ccccttccgt aagaaaggtg cgctttggtg atggctattc tcagcgagcg
     1861 cctgccgggc tgaatgccga cctgaaaacg tacagcgtga cgctttctgt tccccgttgg
     1921 gaggccacgg cgcttgagtc gtttctggct gagcacgggg gctggaaatc ctttctgtgg
     1981 acgccgcctt atgagtggcg gcagataaag gtgacctgcg caaaatggtc gtcgcgggtc
     2041 agtatgctgc gtgttgagtt cagcgcagag tttgaacagg tggtgaactg atgcaggata
     2101 tccggcagga aacactgaat gaatgcaccc gtgcggagca gtcggccagc gtggtgctct
     2161 gggaaatcga tctgacagag gtcggtggag aacgttattt tttctgtaat gagcagaacg
     2221 aaaaaggtga gccggtcacc tggcaggggc gacagtatca gccgtatccc attcagggga
     2281 gtggttttga actgaatggc aaaggcacca gtacgcgccc cacgctgacg gtttctaacc
     2341 tgtacggtat ggtcaccggg atggcggaag atctgcagag tctggtcggc ggaacggtgg
     2401 tccggcgtaa ggtttacgcc cgttttctgg atgcggtgaa tttcgtcaac ggaaacagtg
     2461 acgccgatcc ggagcaggag gtgatcagcc gctggcgcat tgagcagtgc agcgaactga
     2521 gcgcggtgag tgcctctttt gtactgtcca cgccgacgga aacggacggc gctgtttttc
     2581 cgggacgtat catgctggcc aacacctgca cctggaccta tcgcggcgat gagtgcggtt
     2641 atcacggtcc ggcggtcgcg gatgaatatg accagccaac gtccgatatc acgaaggata
     2701 aatgcagcaa atgcctgagc ggttgtaagt tccgcaataa cgtcggcaac tttggcggct
     2761 tcctttccat taacaaactt tcgcagtaaa tcccatgaca cagacagaat cagcgattct
     2821 ggcgcacgcc cggcgatgtg cgccagcgga gtcgtgcggc ttcgtggtga gagcgccgga
     2881 gggggaaagc tattttccct gcgtgaatat ttccggtgag ccggaggagt atttccggat
     2941 ggctccggag gactggctgc aggcagagat gcagggtgag attgtggcgc tggtccacag
     3001 tcaccccggt ggtctgccca ggctgagtga ggccgaccgg cggatgcagg tgcagagtga
     3061 tttgccgtgg tggctggtct gccgggggac gattcataag ttccgctgtg tgccgcatct
     3121 caccgggcgg cgctttgagc acggggtgac ggactgttac acgctgttcc gggatgctta
     3181 tcatctggcg gggattgaga tgccggattt tcatcgcggg gatgactggt ggcgtcacgg
     3241 tcagaatctc tatctggata atctggaggc cacagggctg tatcaggtgc cgttgtcatc
     3301 agcacaaccg ggcgatgtgc tgctgtgctg ttttggttca tcggtgccga atcatgccgc
     3361 catttactgt ggtgatggcg agctgctgca ccatattcct gaacaactga gcaaacgaga
     3421 gaggtatacc gacaaatggc agcgacgcac acactccctc tggcgtcacc gggaatggca
     3481 cgcatctgcc tttacgggga tttgcaacga tttggccgcc gcatcgacct tcgtgtgaaa
     3541 acgggggctg aagccatccg ggcactggcc acacagcttc cggcgtttcg tcagaagctg
     3601 agcgacggct ggtatcaggt acgcattgcc gggcgtgata caggtgaaac ggaattatca
     3661 gcccgtctta atgaaccgct ggcaaatagt gctgtgatcc atatcgtgcc gcgtctggca
     3721 ggagccaaaa gtggcggtgt gtttcaggct gtgctggggg cggctgttat ggcggttgct
     3781 atatggatgc cgggggtagg aattatggcg agtaatctgc tgttttctct cggtgccagt
     3841 atgacgcttg gcggtgttgc acagatgctg gcccctaaac ccaaaactcc ccgtacacag
     3901 acaacggata acggcaaaca gaacacctat ttttcttcac tggataatat ggttgcccag
     3961 ggcaatgttc tgcccgttct gtacggtgaa atgcgcgtgg gatcacgtgt ggtttctcag
     4021 gagatcagca cagcagatga aggtgatggt ggtcaggttg tggtgattgg tcgctgatga
     4081 aaaacgtttt atgtgaaacc gccttcgggc ggttttatcg tttatggagc atgacgaatg
     4141 ggtaaaggca gcagtaaggg gcataccccg cgcgaagcga aggacaacct gaagtccacg
     4201 cagctgctga gtgtgatcga tgccatcagc gaagggccgg ttgaaggtcc ggtggatgga
     4261 ttaaaaagcg tgctgctgaa cagtacgccg gtgctggaca gtgaggggaa taccaatata
     4321 tccggcgtca cggtggtgtt ccgggccggt gagcaggagc agacgccgcc ggagggcttt
     4381 gaatcctccg gttccgagac ggtgctgggt acggaagtga aatacgacac gccgattacc
     4441 cggaccatca cgtctgcaaa catcgaccgt ctgcgcttta ccttcggtgt gcaggcactg
     4501 gtggaaacca cctcaaaggg ggaccggaat ccgtcggaag tccgcctgct ggttcagata
     4561 caacgtaacg gtggctgggt gacggaaaaa gacatcacca ttaaaggcaa aaccacctca
     4621 cagtatctgg catcggtggt ggtgggtaac ctgccgccgc gcccgttcaa tatccggatg
     4681 cgcaggatga cgccggacag caccacagat cagctgcaga acaaaacgct ctggtcgtca
     4741 tacaccgaaa tcatcgatgt gaaacagtgc tacccgaaca cggcactggt cggcgtacag
     4801 gtggattcgg agcagttcgg cagccagcag gtgagccgta attatcatct gcgcgggcgt
     4861 attctgcagg tgccgtcgaa ctataacccg cagacgcggc aatacagcgg tatctgggac
     4921 ggaacgttta agccagcata cagcaataac atggcctggt gtctgtggga tatgctgacc
     4981 catccacgct acggcatggg gaaacgtctt ggtgcggcgg atgtggacaa atgggcgctg
     5041 tatgtcatcg gccagtactg cgaccagtca gtgccggacg gctttggcgg cacggagccg
     5101 cgcatcacct gtaatgcgta cctgaccaca caacgtaagg cgtgggatgt gctcagtgat
     5161 ttctgctcgg cgatgcgctg tatgccggta tggaacgggc agacgctgac gttcgtgcag
     5221 gaccgaccgt cggataaggc gtggacctat aaccgcagta atgtggtgat gccggatgat
     5281 ggcgcgccgt tccgctacag cttcagcgcc ctgaaagacc gccataatgc cgttgaggtg
     5341 aactggattg acccgaacaa cggctgggag acggcgacag agcttgttga agatacgcag
     5401 gccattgccc gttacggtcg taatgttacg aagatggatg cctttggctg taccagccgg
     5461 gggcaggcac accgcgccgg gctgtggctg attaaaacgg agctgctgga gacgcagacc
     5521 gtggatttca gcgtcggcgc agaagggctt cgccatgtac cgggcgatgt tattgaaatc
     5581 tgcgatgatg actatgccgg tatcagcacc ggtggtcgtg tgctggcggt gaacagccag
     5641 acccggacgc tgacgctcga ccgtgaaatc acgctgccat cctccggtac cacgctgata
     5701 agcctggttg acggaagtgg caatccggtc agcgtggagg ttcagtccgt caccgacggc
     5761 gtgaaggtaa aagtgagccg tgttcctgag ggtgttgctg aatacagcgt atgggggctg
     5821 aagctgccga cgctgcgcca gcgcctgttc cgctgcgtga gtatccgtga gaacgacgac
     5881 ggcacgtatg ccatcaccgc cgtgcagcat gtgccggaaa aagaggccat cgtggataac
     5941 ggggcgcact ttgacggcga acagagtggc acggtgaatg gtgtcacgcc gccagcggtg
     6001 cagcacctga ccgcagaagt cactgcagac agcggggaat atcaggtgct ggcgcgatgg
     6061 gacacaccga aggtggtgaa gggcgtgagc tttatgcttc gcctgaccgt ggcagcggac
     6121 gacggcagtg agcggctggt cagcacggcc cggacgacag aaaccacata ccgcttcagg
     6181 cagctggcgc tggggaacta caggctgaca gtccgggcgg taaatgcgtg ggggcagcag
     6241 ggcgatccgg catcggtatc gttccggatt gccgcacctg cagtgccgtc gcggattgag
     6301 ctgacgccgg gctattttca gataaccgcc acgccgcatc ttgccgttta tgacccgacg
     6361 gtacagtttg agttctggtt ctcggaaaag cggattaccg atatcaggca ggttgaaacc
     6421 acagcccgct atcttggcac ggcgctgtac tggatagccg ccagtatcaa tatcaaaccg
     6481 ggccatgatt attattttta cgttcgcagt gtgaacaccg ttggcaaatc ggcattcgtg
     6541 gaggctgttg gtcagccgag tgatgatgca tccggctatc tggatttttt caaaggcgag
     6601 atagggaaaa cccatctggc tcaggagctg tggacgcaga ttgataacgg tcagcttgcg
     6661 cctgacctgg ctgaaatcag gacgtccatt acggatgtca gcaatgaaat cacgcagacc
     6721 gtcaataaga aactggaaga ccagagtgcg gcaattcagc agatacagaa ggttcaggtt
     6781 gatacaaata ataacctgaa cagcatgtgg gctgtgaagc tgcagcagat gcaggacgga
     6841 cgcctttata tcgcgggtat tggtgccggt attgagaaca cccctgacgg catgcagagt
     6901 aaggtgctgc tggcggcgga caggattgcg atggttaatc ctgcgaatgg caacacaaaa
     6961 ccgatgtttg ttggtcaggg cgatcagata ttcatgaacg acgtgttcct ggaacgcctg
     7021 acggccccca ccattaccag cggtggaaat ccaccggcat tttccctgac accggacgga
     7081 aagctgactg ctaaaaatgc ggatatcagt ggcagtgtga atgcgaactc cgggacgctc
     7141 aacaacgtca cgattaatga gaactgtcag attaagggga aactgtcagc caatcagatt
     7201 gaaggcgata ttgtcaaaac agtgggtaag gctttcccgc gggactcccg ggcaccggag
     7261 cggtggccat cagggaccat taccgtcagg atttatgacg atcagccttt tgacaggcaa
     7321 attgttattc cagcggtggc attctgcggc gctaaacatg agcgggagaa taacgatatt
     7381 tattcgtcat gccgcctgat agtgaagaaa aatggtgctg aaatttataa ccgtaccgcg
     7441 ctggataata cgctgattta cagtggtgtt attgatatgc cagctggtca cggccacatg
     7501 acgctggagt tttcggtgtc agcatggctg gtaaatgact ggtatcccac agcaagtatc
     7561 agcgatttgc tggttgtggt gatgaagaaa gccaccgcag gcatcagtat cagctgaatt
     7621 ttataaccca tatacgggcg ccagaaatgg cgcctttttt attgcagaaa agcgagaggt
     7681 aattatgcgt aaagtttgtg cagccatttt gtccgcagcc atctgtctgg ccgtatccgg
     7741 tgcgcctgca tgggcgtctg agcagcaggc cacactgagc gcagggtatc ttcatgcccg
     7801 tacgaacgct cccggcagcg atgatctgaa cgggattaac gtgaaatacc gttatgagtt
     7861 tacggacacg ctggggctga ttacgtcatt cagttatgcc aacgctgaag atgagcaaaa
     7921 aacgcattac agcgataccc gctggcatga agattccgtg cgtaaccgct ggttcagcgt
     7981 gatggcgggg ccgtctgtgc gcgtgaatga atggttcagc gcgtatgcga tggcgggtat
     8041 ggcttacagc cgtgtttcga ctttctccgg agattatctc cgcgtaactg acaacaaggg
     8101 gaaaacgcac gatgtgctga ccggaagtga tgacggtcgc cacagcaaca cgtctctggc
     8161 gtggggagct ggcgtgcagt ttaacccgac cgaatccgtg gccgttgacg tcgcttatga
     8221 aggctccggc agcggtgact ggcgtaccaa cagtttcatc gtgggtgtcg gttataaatt
     8281 ctgattagcc aggtaacaca gtgttatgac agcccgccgg ttcaggcggg cttttttgtg
     8341 gggtgaatat ggcagtaaag atttcaggtg tactgaaaga cggcacagga aaaccggtac
     8401 agaactgcac aatccagctg aaagcaaaac gtaacagcac cacggtggtg gtgaacacgc
     8461 tggcctcaga aaatccggat gaagccgggc gttacagtat ggacgttgag tacggtcagt
     8521 acagcgttat tctgttggtg gaaggattcc cgccgtcaca tgccgggacc atcaccgtgt
     8581 atgaagattc ccgacccggt acgctgaatg attttctcgg tgccatgacg gaggatgatg
     8641 cccgtccgga ggcactgcgc cgttttgagc tgatggtgga agaggtggcg cgtaacgcgt
     8701 ccgcggtggc acagaacacg gcagccgcga agaagtcagc cggcgatgcc ggcacatcag
     8761 cccgtgaggc ggcaacccat gcgactgatg ctgcaggctc agcacgtgca gccagcacat
     8821 cagccgggca ggccgcgacg tcggctcagt cagcgtcttc cagcgcagga acggcatcaa
     8881 caaaggctac tgaagcatca aaaagtgctg ccgctgcaga gtcctcaaaa agcgcggcag
     8941 ctaccagtgc cggtgcggcg aaaacgtcag aaacgaatgc ggcagcgtca caaaaatctg
     9001 cagccacttc tgcatccgca gcgaccacaa aggcgtcaga agctgccacc tcagcccggg
     9061 atgcggcggc ctcaaaagag gcagcgaaat catcagaaac gaacgcatca tcaagcgcca
     9121 gtagtgccgc ttcctcggca acggcggcag gaaattccgc gaaggcggca aagacgtccg
     9181 agacgaacgc caggtcttct gaaacggcag cgggacagag tgcctcagct gcggcaggct
     9241 caaaaacagc ggcagcatca tctgccagtg ccgcgtcaac aagtgccggg caggcctcag
     9301 ccagtgccac cgctgccgga aagtcggcag aaagtgccgc ctcgtctgct tcaacagcca
     9361 caacgaaggc tggcgaagcc actgaacagg ccagtgcagc agcgaggtct gcttccgcag
     9421 cgaagacatc cgagacgaac gcgaaagcgt cggaaaccag cgcagaatcc tcaaaaacgg
     9481 ctgccgcatc gtccgccagt tcggcggcgt catcggcatc atcggcgtca gcttcaaaag
     9541 atgaggcgac cagacaggcg tcagcagcga agggcagcgc cacgacagca tccacgaagg
     9601 cgacagaggc agctggcagt gcgacggcgg cagcacagag caaaagtacg gcggaatccg
     9661 cggcaacgcg cgccgagaca gcagctaaac gggcagagga tattgcatcc gccgtggcgc
     9721 ttgaggatgc aagtacgacg aaaaagggga tagtacagct cagcagtgcg accaacagta
     9781 cgtctgaaac gctggcggca acgccaaagg cagtaaaatc agcctatgac aatgcagaga
     9841 aacgtctgca gaaagaccag aacggcgctg atatacccga taagggacgc ttcctgaaca
     9901 acattaacgc ggtcagtaaa acagactttg ctgataagcg tggtatgcgt tatgtgcggg
     9961 ttaacgctcc tgcaggtgca acatctggaa aatattaccc tgttgttgtt atgcgttctg
    10021 ctggctcagt aagcgaactg gcatcaaggg tcattatcac cacggcaccg cgaaccgcag
    10081 gcgatccgat gaataactgc gagtttaacg gatttgttat gcctggtggc tggactgaca
    10141 gggggcgtta tgcttatgga atgttctggc aatatcaaaa caatgaacga gccatccact
    10201 caataatgat gagtaataag ggcgatgatt tgcgctctgt gttctatgtt gatggcgctg
    10261 ctttccctgt ttttgcgttt atcgaagatg gcctgtcaat atccgcacct ggtgctgatc
    10321 tcgttgttaa tgatacgacc tataagtttg gggcaacaaa tccagcgact gaatgtatcg
    10381 cggcggacgt tatccttgat tttaagagtg ggcgtggttt ttatgagtct cattcgttaa
    10441 tcgttaacga taacttgtcg tgcaaaaaac tttttgccac agacgaaatt gtagcgcgtg
    10501 gtggtaatca gattcgaatg ataggtgggg agtatggtgc attatggcgt aatgatggcg
    10561 ctaaaactta cctgctgctt accaatcaag gtgatgttta tggtggctgg aatacattaa
    10621 gaccgtttgc tattgataac gcaaccggcg aactggttat tggaaccaaa ctgtccgcaa
    10681 gtctgaacgg taatgcatta acagcaacaa agctgcaaac gccaagactg gtttctggtg
    10741 ttgagtttga tggttccaaa gatattactt taaccgccgc gcatgtggct gcttttgcca
    10801 gaagggcaac ggatacatat gccgatgcgg atggtggcgt tccctggaat gccgaatcag
    10861 gcgcttacaa tgtcacccgc tctggcaaca gctatattct ggttaacttc tataccggag
    10921 tcggaagttg ccggacattg cagatgaagg cgcattacag aaatggaggt ctgttctacc
    10981 gttcctcaag agatggctat ggttttgagg aagactgggc agaagtttat acctcgaaaa
    11041 atcttccacc agaaagctac ccagtcggtg caccaatccc gtggccatca gataccgttc
    11101 cgtctggtta tgccctgatg caggggcaga cttttgacaa atctgcttac ccgaaacttg
    11161 cagccgctta tccgtcaggc gtgatccctg atatgcgtgg ctggacgatt aagggcaaac
    11221 ctgccagtgg tcgggccgta ttgtctcagg aacaggacgg cattaaatcg cacacccaca
    11281 gcgccagcgc atccagtacg gatttgggga cgaaaaccac atcgtcgttt gattacggca
    11341 ctaaatccac gaataacacc ggggcgcata cccatagtgt tagcggtacg gctgcttcag
    11401 ccggtgcaca tacccattcg ataacatttg tttcaggtgg caccaaaggt gctccgggaa
    11461 gtggatcacc tgattattct aaatacagtg ttaacacttc ttctgcaggc gctcatacgc
    11521 actctgtatc gggtactgct gcaagcgcag gtgcacacgc acatactgta ggtattggtg
    11581 cgcatacgca ctcggttgcg attggttcac atggacacac catcaccgtt aacgctgctg
    11641 gtaacgcgga aaacaccgtc aaaaacatcg catttaacta tattgtgagg cttgcataat
    11701 ggcattcaga atgagtgaac aaccacggac cataaaaatt tataatctgc tggccggaac
    11761 taatgaattt attggtgaag gtgatgcata tattccgcct catacaggtc tgccagcaaa
    11821 cagtaccgat attgcaccgc cagatattcc ggctggcttc gtggctgttt tcaacagtga
    11881 tgagtcatcg tggcatctcg ttgaagatca tcggggtaaa acggtttatg acgtggcttc
    11941 cggcgacgcg ttatttattt ctgaactcgg tccgttaccg gaaaatgtta cctggttatc
    12001 gccggaaggg gagtttcaga agtggaacgg cacagcctgg gtgaaggata cggaagcaga
    12061 aaaactgttc cggatccggg aggcggaaga aacaaaaaac aacctgatgc aggtagccag
    12121 tgagcatatt gcgccgcttc aggatgctgc agatctggaa atcgcaacgg aggaagaaat
    12181 ctcgttgctg gaagcatgga aaaagtatcg ggtattgctg aaccgtgttg atacgtcaac
    12241 tgcacaggat attgaatggc cagcactgcc gtagggtaaa acatataaat tctataatta
    12301 gatgtatctt tccatttacg gcaaggaagg gggcttggaa gacgtaaagc atctcacacc
    12361 gagattattt tttatatgtc aggtgtctga agttttgctt tggctcttaa aatggtttgc
    12421 cgcgaggttt tgaattcccg ggcaatggca cttatactta cacctgactt aattcgttcg
    12481 aataccgcct gtttctgttc ttcatttaac acaggtggtc gaccaaaacg tttccctgcg
    12541 ccgcgggctc ttactatccc ggaatgagtg cgttcaagta aaaggtctcg ttcaaattca
    12601 gcgactgctg aaattacttg catcatcatt tttcctgttg gactggtcag gtcaatgccc
    12661 cccaatgcta agcaatgcac tctgatacct gtttcggtca gttgttccac tgttttcctg
    12721 atatccattg cattacaacc aaggcgatcc agttttgtca caatcaattg atcaccacat
    12781 ttcaggcgag caagcaaccg gttaaaacca ggacgctcac tggttgctgc tgagccgcta
    12841 atgtgttctt cgattatttg ctgaggtttg attttaaaac ctgcactttc gatttcccgg
    12901 cgttgatttt cggtggtctg atccagcgtt gatatccgac agtaagcaaa aattcgagac
    12961 atagtgagac tctatacgaa attggtgttc atatcataat gcatctcaga aaataattat
    13021 gattattttt gtgcatattt gtatgtacac gttcgaaaat aaacgaatgc gtatgcaacc
    13081 ccgtaatttt ggtgagaccc aaaatcgatt ttgtgaaaaa tggctttaac tcggtttgtt
    13141 tttcgagttc cgggcggact caaggaagaa gaatagtgtt gcgtgttatt ttaaccagat
    13201 ttcaagttgt ttggt
//
LOCUS       DAPHKZ010000124        13214 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.124, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000124 DAPHKZ010000000
VERSION     DAPHKZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13214
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.124"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(158..370)
                     /gene="cspH"
                     /locus_tag="RH288_003700"
     CDS             complement(158..370)
                     /gene="cspH"
                     /locus_tag="RH288_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspH"
                     /protein_id="HDV4032714.1"
                     /translation="MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEV
                     LIPGLRVEFCRVNGLRGPTAANVYLS"
     gene            656..868
                     /gene="cspG"
                     /locus_tag="RH288_003701"
     CDS             656..868
                     /gene="cspG"
                     /locus_tag="RH288_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspG"
                     /protein_id="HDV4032715.1"
                     /translation="MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRT
                     LNENQKVEFSIEQGQRGPAAANVVTL"
     gene            879..1067
                     /locus_tag="RH288_003702"
     CDS             879..1067
                     /locus_tag="RH288_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDV4032716.1"
                     /translation="MTQHLHFRCPCCHGSQYRTSAFDVTERNPLGAKCIFCKSTMITF
                     DNVALQIRTDHAPLDFTK"
     gene            1042..1272
                     /gene="ymcE"
                     /locus_tag="RH288_003703"
     CDS             1042..1272
                     /gene="ymcE"
                     /locus_tag="RH288_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmcE"
                     /protein_id="HDV4032717.1"
                     /translation="MRRWISQNNIRLPRGAFFISALFFFNAVCIVSDNLLIIESFGEM
                     AYNISYLTRVPGTNTLLACCCLLRPEEVNSEY"
     gene            1262..1435
                     /locus_tag="RH288_003704"
     CDS             1262..1435
                     /locus_tag="RH288_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HDV4032718.1"
                     /translation="MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKM
                     TGLESYDVKIKIM"
     gene            complement(1484..2557)
                     /locus_tag="RH288_003705"
     CDS             complement(1484..2557)
                     /locus_tag="RH288_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDV4032719.1"
                     /translation="MAENKRTRWQRRPGTTGGKLPWNDWRNATTWRKATQLLLLAMNI
                     YIAITFWYWVRYYETASSTTFVARPGGIEGWLPIAGLMNLKYSLVTGQLPSVHAAAML
                     LLVAFIVISLLLKKAFCSWLCPVGTLSELIGDLGNKLFGRQCVLPRWLDIPLRGVKYL
                     LLSFFIYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISVTVLLIASLFI
                     RHAWCRYLCPYGALMGVVSLLSPFKIRRNAESCIDCGKCAKNCPSRIPVDKLIQVRTV
                     ECTGCMTCVESCPVASTLTFSLQKPAANKKAFALSGWLMTLLVLGIMFAVIGYAMYAG
                     VWQSPVPEELYRRLIPQAPMIGH"
     gene            complement(2629..5373)
                     /gene="torS"
                     /locus_tag="RH288_003706"
     CDS             complement(2629..5373)
                     /gene="torS"
                     /locus_tag="RH288_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415513.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HDV4032720.1"
                     /translation="MNLTLTRRLWMGFALMALLTLTSTLVGWYNLRFISQVEKDNTQA
                     LIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSLKINALLQALREQ
                     GFDTTAIEQQEQEISRSLRQQGELVGQRLQLRQQQQQLSQQIVAAADEIARLAQGQAN
                     NATTSAGATQAGIYDLIEQDQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVM
                     NLGLEQIQKNAPTLEKQLNNAVKILQRRQIRIEDPGVRAQVATTLTTVSQYSDLLALY
                     QQDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLL
                     LLGMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPFPETAGVRELDTIG
                     RLMDAFRSNVHALNRHREQLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAA
                     MSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAG
                     GKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATAIADDMPCALMGDPRRIRQVI
                     TNLLSNALRFTDEGYIILRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG
                     GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVATAPVPKTVNQAVRLDGL
                     RLLLIEDNPLTQRITIEMLKTSGAQIVAVGNAAQALETLQNSEPFAAALVDFDLPDID
                     GITLARQLAQQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYL
                     QLQVNNDQSLDVSQLNEDAQLMGTEKIHEWLVLFTQHALPLLDEIDIARASQDSEKIK
                     RAAHQLKSSCSSLGMHIASQLCAQLEQQPLSAPLPHEEITRSVAALEAWLHKKDLNAI
                     "
     gene            5456..6484
                     /gene="torT"
                     /locus_tag="RH288_003707"
     CDS             5456..6484
                     /gene="torT"
                     /locus_tag="RH288_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HDV4032721.1"
                     /translation="MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASTPLKAKRA
                     WKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWG
                     AEAILLGSSTTSFPDLQKQVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQ
                     WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQE
                     MLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASD
                     QMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYFY
                     QHTSAAKK"
     gene            complement(6457..7149)
                     /gene="torR"
                     /locus_tag="RH288_003708"
     CDS             complement(6457..7149)
                     /gene="torR"
                     /locus_tag="RH288_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
                     /protein_id="HDV4032722.1"
                     /translation="MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQN
                     QSVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTK
                     PLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
                     AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQ
                     HGEGYFLAADVC"
     gene            7279..8451
                     /gene="torC"
                     /locus_tag="RH288_003709"
     CDS             7279..8451
                     /gene="torC"
                     /locus_tag="RH288_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HDV4032723.1"
                     /translation="MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTST
                     TEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
                     KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAK
                     GDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGD
                     VQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHG
                     APEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK"
     gene            8451..10997
                     /gene="torA"
                     /locus_tag="RH288_003710"
     CDS             8451..10997
                     /gene="torA"
                     /locus_tag="RH288_003710"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HDV4032724.1"
                     /translation="MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAAT
                     DAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
                     QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTH
                     EYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEK
                     DGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIP
                     IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGLRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDI
                     FRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGG
                     PGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDV
                     VRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIG
                     TSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS"
     gene            10994..11593
                     /gene="torD"
                     /locus_tag="RH288_003711"
     CDS             10994..11593
                     /gene="torD"
                     /locus_tag="RH288_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HDV4032725.1"
                     /translation="MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLL
                     KSEPPLTAAVNELENRIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQ
                     EIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTA
                     LWQWLPEFVARCRQYDSFGFYAALSQLLLVLVECDHQNR"
     gene            complement(11745..12050)
                     /gene="cbpM"
                     /locus_tag="RH288_003712"
     CDS             complement(11745..12050)
                     /gene="cbpM"
                     /locus_tag="RH288_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HDV4032726.1"
                     /translation="MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWV
                     FDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP"
     gene            complement(12050..12970)
                     /gene="cbpA"
                     /locus_tag="RH288_003713"
     CDS             complement(12050..12970)
                     /gene="cbpA"
                     /locus_tag="RH288_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HDV4032727.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIF
                     GQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
                     NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVS
                     PWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMP
                     PKPDENTAALWQQLADAQSSFDPRKDWGKA"
BASE COUNT         3223 a         3354 c         3445 g         3192 t
ORIGIN      
        1 aactggctgt taaatggcat ttataactat taggtgcaga gatattcgct taaatggatt
       61 agtttctttg tggaaaagta actgatgtta taatgtatga tgttgactat tgcactattc
      121 caataaaacc agtcagcttt aaacaagcag cgtcatatta agagagataa acatttgccg
      181 ctgttggtcc tcgcaggcca tttacgcggc aaaattccac acgtaatcct ggtataagca
      241 cttctgcgtc gcggggagtg aatgcggaaa tatggacctg aacttcttta cgaccgtcgg
      301 aggggataat gaatcctttg ccgcttttgc gatcaaaggt tttgacaatt cctgtcattt
      361 tacgggacaa acaaattcct tactgaaaat actgcgctgc actatacggg gttaataaaa
      421 taaagccagc gatatttaag accgccggac ggctaaaata aaatttgctt aatctcaatt
      481 atcatgcgtt aatagctgcg tcggtttgaa agacagacag catacaaagt agtttactaa
      541 agcagttctc attatcaggc attatcccct tcttttgagt ctctctcctg aacactaagt
      601 agtttctgta ttaaagccct gtttgccgaa aggcccaaaa tgaaggaagt aaaatatgtc
      661 taataaaatg actggtttag taaaatggtt taacgcagat aaaggttttg gctttatcac
      721 tcctgatgat ggcagcaaag acgttttcgt ccatttcacc gccatccaga gcaatgaatt
      781 ccgcacgctg aacgaaaatc agaaagttga attttctatt gagcaggggc aacgtggccc
      841 cgcggcagcg aacgttgtta cgctctaagg ttgccattat tactcaacat ctccatttcc
      901 gctgtccatg ttgtcatggt tcacagtacc gcacatcggc attcgatgtg acggagcgaa
      961 accctttggg cgctaagtgt attttttgta aatcgacgat gatcaccttt gataacgtcg
     1021 cgctgcaaat acgcactgac catgcgccgc tggatttcac aaaataatat caggctccct
     1081 cgtggagcct tttttatatc tgccttattt ttcttcaacg ctgtatgtat agtaagcgat
     1141 aacctgttga ttattgaatc tttcggggag atggcttata acatttctta cctgaccagg
     1201 gtaccgggaa ccaacacctt actggcgtgt tgctgtcttt taagaccaga agaggttaac
     1261 agtgaatatt gaagagttaa aaaaacaagc cgaaacggaa atcgccgact ttatcgcgca
     1321 aaaaatcgcc gagctgaaca agaatacagg gaaagaagtc tctgaaattc gcttcaccgc
     1381 acgagaaaaa atgaccgggc ttgaaagtta tgatgtcaaa atcaaaataa tgtgattttg
     1441 tgaacatcac cccgtgcgag gtgatgttcc gcttgttgct aatttagtga ccaatcattg
     1501 gcgcttgtgg aattaagcgt cggtacaatt cctccggcac cgggctttgc catactcccg
     1561 catacattgc gtaaccaatc accgcaaaca taatccccag aaccagtagc gtcattaacc
     1621 agccagacaa cgcaaaggct tttttatttg ccgcaggttt ttgcagtgaa aaggtcaatg
     1681 ttgaggctac cggacatgac tctacgcaag tcatacagcc ggtacattcc actgttcgta
     1741 cctgaattaa tttatcgacc gggatccgtg atgggcaatt ttttgcgcat ttgccacagt
     1801 cgatacaact ttcggcattg cgacgaatct taaacggcga caatagcgaa accacgccca
     1861 tcagcgcgcc atatgggcaa agataacgac accaggcatg gcgaataaac aggctggcaa
     1921 tcagcaaaac ggtcacgctg attaatgtcg cggtccccat atgacgaaag aaatcgagca
     1981 ttttaacgtc catcaccacg ctgtagggcg acaacataaa atagtgaatc gcctgagcgg
     2041 gcatcaataa cgcgatatag ataaaaaaac tcaacagcaa atacttcacg ccgcgcagag
     2101 gaatatccag ccagcgggga aggacacatt gccgaccaaa cagtttgtta ccgagatcgc
     2161 cgattaattc agaaagcgta ccaaccgggc ataaccatga gcaaaaggcc tttttgagta
     2221 atagactgat gacgataaaa gcgaccaata acagcatcgc ggcggcgtgg acggacggta
     2281 actgacctgt tacaaggcta tatttcagat tcatcagccc ggcaatcggt agccagcctt
     2341 cgatacctcc cggtctggcg acaaatgtcg tgctacttgc cgtttcgtaa tagcgcaccc
     2401 aataccagaa cgtgatggca atataaatat tcattgccaa cagtaataat tgcgtcgctt
     2461 tacgccaggt cgtggcatta cgccagtcat tccacggtaa tttgccgccc gtcgtgcctg
     2521 gccgccgctg ccagcgggtt cttttattct ctgccatgat tttgccagtc cgttaagttg
     2581 tataccaaat gccactattc tagttgttct taactggctg atattgattc aaatcgcgtt
     2641 caggtctttc ttatgcaacc atgcttccag agcggcaaca ctgcgtgtaa tttcttcgtg
     2701 tggaaggggg gcagataatg gctgctgctc cagttgtgcg catagctggc tggcgatatg
     2761 cattcccaga ctcgagcaac tgctttttag ctgatgcgcg gcacgcttta ttttctcgct
     2821 atcctgactg gcgcgggcaa tgtcgatttc atcgagaagc ggcagggcat gttgtgtaaa
     2881 taataccagc cattcgtgga tcttctccgt ccccattaac tgagcatctt cattgagttg
     2941 cgatacatcc agcgattgat cattattgac ttgcagttgg agatagtgcg ccagtaactg
     3001 accgagcact tcacgcggca ccggtttagg gataatcccg cggaataatg aactggtacg
     3061 ctggcgcagc gtttcgtcaa tgacatgggc gctaaagcca atcaaaacca gcgacggata
     3121 ttgctgtgcc agttgtcggg caagcgtaat gccgtcgata tccggcagat caaaatccac
     3181 cagtgcggca gcaaacggtt cgctattttg cagtgtctct aaagcctgcg cggcattgcc
     3241 aacagcaaca atctgcgcac cactggtttt cagcatctca atggtaattc gctgggttag
     3301 cgggttatct tcaattaaca gcaaacgtaa accgtcaaga cgcaccgcct gattgactgt
     3361 ttttggcacg ggtgccgtgg caacacgtaa cggcaagcgt aaacaaaaac agcttccaac
     3421 ctccggcgtg ctggtggcgc tcagttcgcc gcccatcgcc tgggccagac ggctactgat
     3481 agtcagtccc agcccggtgc cgccgcgttt gccgcttacc tgcacaaatg gctggaagat
     3541 ttctgccagt ttcgcgggat caataccgca gccgctgtct tccacttcga ccagccattg
     3601 ctcgccatca gtgcgactac gcaggataat gtacccttcg tcagtaaaac gcagggcgtt
     3661 gctcaacagg ttggttataa cctgacgaat acgtcgtgga tcgcccatta acgcgcacgg
     3721 catatcatcg gcaattgccg ttgccaggcg aatcgggcga cctttcaccc gtccgctcat
     3781 taattgcagg gtactttcca gcagcgggcg cggttcaaag ggctcatcgc tgaccgaaac
     3841 attcttgcca cctgcttcga tagcggaata atcgagaata tcgttgagga tggtcagcaa
     3901 cgattcacca gagtcagtaa ttgcccgcaa atcatcacgc tgggcgttaa gtgcggggtt
     3961 atctgccagc agttgagcag tgccgagaat accgtacagc ggtgtgcgga tctcatggct
     4021 catcgccgcc agaaacgccg attttgcctg gctggctttt tctgcttccg cccgtgcctg
     4081 tcggtgttct atcaccagtt cctgcaattc agctgtacgc gctttgacct gcgccgccag
     4141 ctgttcgcgg tggcgattca gtgcatgaac attgctgcga aacgcatcca tcagccgccc
     4201 gatggtatcc agctcccgta cgccagcggt ttccgggaaa ggggagtcaa tatcaccgtc
     4261 cagcagccgt tgcagcgcct gcgtttgttc ggcaagtgga cgcgtgactg agcgataaac
     4321 cacgcgccag aggatcagaa tcagtgcgca aagtgaaacc atccccagca ataacaggct
     4381 gtattgcccg cgtgcactcg ctttttccag atgcgccagt ccgtgctgat tacgcagctc
     4441 aatggtgtcg accagctgac tgacttcgct actaaactgc gcgaactggg cgatgttatt
     4501 ttgtgcgaga gtttgtaggt gattgctgat ttcactgtcc tgctgataca gcgccagcaa
     4561 atcgctatat tggctaacgg tagttaacgt tgttgcgacc tgcgcacgaa cacccggatc
     4621 ttcaatgcgt atttgccgac gttgcagaat tttcaccgca ttattgagct gcttttccag
     4681 cgttggtgca tttttctgga tctgctccag ccccagattc atcaccattt gctgcacccg
     4741 cagagcgcta aggcgcagtt cattcatctg gttaacatac tcaagatcga tatcaatcag
     4801 ccgatcgagt gcactttcag cagcctgacg ctgatcttgt tcgatcaaat cgtaaatccc
     4861 ggcctgggtc gctccagcgg aagttgtcgc attattcgcc tgaccttgcg ccaggcgtgc
     4921 gatctcatcg gcggcagcga ctatctgctg actgagttgc tgttgttgct ggcgcagttg
     4981 caaacgctgc cccaccagtt ccccttgctg acgtaacgaa cgggagatct cctgctcctg
     5041 ttgttcaata gcggtggtat caaaaccttg ttcccgtaac gcttgcagca acgcattaat
     5101 cttcaggctt tgtgcggtga gcattcgccc ctgcgcctgc cacatctttt cgttatcggc
     5161 actggtcagg ttctgcgcgg cgaaaagttc ccaggcgctg gcttcgctca actggcgcgc
     5221 catattcatg gtaggaatca atgcctgagt gttgtctttt tccacctggc tgataaagcg
     5281 caggttgtac catcccacca gggtactggt cagggttaac agcgccatca gggcaaagcc
     5341 catccagagt cttcgggtca gggttaaatt cacggtcggt gcactttagg tgaaaaaggt
     5401 tgagtcgcaa agcggaatgc atctagcata aagccttatt attgatgagg ctatcatgcg
     5461 cgtactgcta tttttacttc tttccctttt catgttgccg gcattttcgg ctgataacct
     5521 gttgcgctgg catgatgcgc agcatttcac ggtgcaagcc tctacgccgc ttaaagccaa
     5581 acgcgcatgg aaactgtgcg cgctttatcc cagcctgaaa gattcatatt ggttatcgtt
     5641 gaactatggt atgcaggagg ctgctcgccg ctacggtgtg gatttaaaag tgctggaggc
     5701 aggcggctac agccagttgg ctacccagca agcacaaatc gaccagtgta aacagtgggg
     5761 cgcagaggcc attttgctcg gtagtagcac gacctcattt cccgacctgc aaaagcaggt
     5821 agcaagtctg ccggtgatcg aactggtaaa tgctattgat gctccccagg tgaaaagccg
     5881 cgttggtgtg ccctggtttc agatgggcta tcaaccgggg cgatatctgg tgcaatgggc
     5941 gcacggtaaa ccactgaatg tgctgttgat gcccggaccc gataacgccg ggggcagtaa
     6001 ggagatggtc gagggttttc gcgcagccat tgccggaagc ccggtgcgta ttgttgatat
     6061 tgcgcttggt gataacgata ttgaaatcca gcgtaacctg ttgcaggaga tgctggaacg
     6121 ccatccagaa atcgacgtcg ttgccggaac ggccattgcg gcagaggcgg caatggggga
     6181 agggcgtaac ctgaaaacgc cgcttaccgt ggtgtcgttt tatctttcac atcaggtgta
     6241 tcgcgggctg aagcggggaa gagtgattat ggctgccagc gatcaaatgg tctggcaggg
     6301 ggaactggcg gttgagcagg ccatcaggca attacagggg caatcggttt ctgataatgt
     6361 cagcccaccg attttagttc tgacgccgaa aaatgccgac cgtgaacata ttcgccgctc
     6421 gctgtcacca gggggatttc gtccggtcta tttttatcag cacacatcag cggctaagaa
     6481 ataaccttca ccatgttgcg tcaccagtaa atccgcgctg agtttatgac gtaaacgacg
     6541 aattaacaca tcgacggtgc gcaggtcagg gttttccacc cgacgcgcag aaagcatacg
     6601 tagcagacgt tcacggctga gaatttcgcc cggattcgtc acaaatgcca ccaacatttc
     6661 atactctgcg cgggtcagtt taatcggctc gccatcccgc tccagcgtat ggcgcgacac
     6721 attcaggcaa taaccggcaa agcgatagca gttgtcctga gtgtgcggtt gagcttgtcg
     6781 cgcgaggtcg attcgccaga gcagattttt cacccgtact accagttcgc gcagttccag
     6841 cggtttggtg acgtaatcgt ctgcgcccat ttccagccca acaatacggt caatccgatc
     6901 gctgcgtccg gtaaccagaa taatccccac cgttgagcgt tctcgcaggg cgcgggttaa
     6961 catcaggcca ttttcatcgg gtaagttgat atccagcaga attaaatcta ccgactgatt
     7021 ctgcataatt tcccgtagcc cggcaccgct cgccgtaacg gaaacggtat acccctcctg
     7081 agtgaagtag gattgtaatc gcgcctgggt aaccggctca tcttcaacaa taacaatgtg
     7141 atgtggcatc agagggtttt actcattctg ttcatatctg ttcatattct gccgtaagcc
     7201 gttcatcctg accagtgccg ctgttcatat ttgctcatta agatcgcttc actaaaccat
     7261 aattctacag gggttattat gcggaaactc tggaacgcgc tacgccgacc cagtgctcgt
     7321 tggtcggtac tggcgctggt cgcaattggg attgtgattg gcattgcgct gattgtattg
     7381 ccacacgttg ggatcaaagt caccagcaca accgaatttt gtgtcagttg ccacagtatg
     7441 caaccggtgt atgaagaata taaacagtcg gtgcatttcc agaacgcctc cggcgtgcga
     7501 gctgaatgcc atgactgtca tatcccgccg gatattccag gcatggtgaa gcgcaaactg
     7561 gaagcgagca atgatatcta ccagaccttt attgctcact ccattgatac acctgaaaaa
     7621 ttcgaagcca aacgcgcgga acttgccgag cgtgaatggg cgcgaatgaa agaaaacaac
     7681 tcggcaacct gccgctcctg ccataactac gatgcgatgg atcatgcgaa gcagcatcct
     7741 gaagcagcac gtcagatgaa ggtggcagcg aaagataatc aatcctgcat cgactgtcat
     7801 aaaggtattg cccaccagtt accggatatg agtagcggct tccgtaagca gttcgatgag
     7861 ctgcgcgcca gtgctaatga cagtggtgac acgctgtact ctattgatat taagccaatt
     7921 tatgcggcga aaggcgataa agaagcctct ggttctctgc tgcctgcttc ggaagtgaaa
     7981 gtccttaaac gtgacggcga ctggctgcaa attgaaatta ccggctggac ggaaagcgcc
     8041 ggacgtcagc gtgtactcac ccaattccca ggtaaacgca tctttgttgc ctcgattcgt
     8101 ggtgatgtgc agcagcaggt aaaaacgctg gagaaaacca ccgttgccga caccaatacc
     8161 gagtggagca agttgcaggc cactgcgtgg atgaagaaag gcgacatggt gaacgatatc
     8221 aaaccgatct gggcttatgc ggattcgttg tacaacggca cctgtaacca gtgccacggc
     8281 gcaccggaaa tcgcccactt tgacgctaac ggttggatcg gcacgctcaa cggcatgatt
     8341 ggctttacca gtctcgataa acgtgaagaa cgcaccttgt tgaaatatct gcaaatgaat
     8401 gcgtctgaca ccgcaggtaa ggctcacggc gataagaagg aagaaaaata atgaacaata
     8461 acgatctctt tcaggcatca cgtcggcgtt ttctggcaca actcggcggc ttaaccgtcg
     8521 ccgggatgct ggggccgtca ttgttaacgc cgcgacgtgc gactgcggcg caagcggcga
     8581 ctgacgctgt catctcgaaa gagggcattc ttaccgggtc gcactggggg gctatccgcg
     8641 cgacggtgaa ggatggtcgc tttgtggcgg caaaaccgtt cgaactggat aaatatccgt
     8701 cgaaaatgat tgccggattg ccggatcacg tacacaacgc ggcgcgtatt cgttatccga
     8761 tggtacgcgt ggactggctg cgtaagcgcc atctcagcga tacctcccag cgcggtgata
     8821 accgttttgt gcgcgtgagc tgggatgaag ccctcgacat gttctatgaa gaactggaac
     8881 gcgtgcagaa aactcacggg ccgagtgcct tgctgaccgc cagtggttgg caatcgacgg
     8941 ggatgttcca taacgcttcg gggatgctgg cgaaagctat tgccttgcat ggtaatagcg
     9001 ttggtacggg cggagattac tctaccggtg ctgcgcaggt gatcctgccg cgcgtagtcg
     9061 gttcgatgga agtgtatgaa cagcaaacct cctggccgct ggtattgcag aacagcaaaa
     9121 ccattgtgct gtggggctcc gatttgctga aaaaccagca agcgaactgg tggtgcccgg
     9181 atcacgatgt ttatgaatat tacgcgcagc taaaagcgaa agtcgccgcc ggtgaaattg
     9241 aggtcatcag catcgatccg gttgtcacat ccacccatga gtatctgggg cgcgagcatg
     9301 tgaagcacat tgcggttaac ccgcaaactg acgtgccgct gcaactggcg ctggcacata
     9361 cgctgtacag tgaaaacctg tacgacaaaa acttccttgc taactactgt gtgggttttg
     9421 agcagttcct gccgtatctg ctgggtgaga aagacggtca gccgaaagat gccgcatggg
     9481 ctgaaaaact gaccggcatt gatgccgaaa ccattcgtgg gctggcgcgg cagatggcgg
     9541 cgaacagaac gcaaattatt gctggctggt gcgtgcagcg tatgcagcac ggtgaacagt
     9601 gggcgtggat gattgtggtt ctggcggcga tgctggggca aattggcctg ccaggtggtg
     9661 gttttggttt tggctggcac tacaacggcg caggcacgcc ggggcgtaaa ggcgttattc
     9721 tgagtggttt ctccggctct acgtcgattc cgcctgttca cgacaacagt gactacaaag
     9781 gctacagcag cactattccg attgcccgtt ttatcgatgc gatcctcgaa ccggggaaag
     9841 tgatcaactg gaacggtaaa tcggtaaaac tgccgccgct gaaaatgtgt atttttgccg
     9901 gaactaaccc attccatcgc catcagcaga tcaaccgcat tattgaaggc ttgcgcaagc
     9961 tggaaacggt tatcgccata gataaccagt ggacctcaac ctgccgcttt gccgatatcg
    10021 tactgcctgc gaccacgcag tttgagcgta acgatctcga ccagtacggc aatcactcca
    10081 accgtggcat tatcgccatg aaacaggtgg tgccgccgca gttcgaggcg cgcaacgact
    10141 tcgatatttt ccgcgagctg tgccgtcgct ttaatcgcga agaagccttt accgaagggc
    10201 tggacgaaat gggctggctg aaacgcatct ggcaggaagg tgtacagcaa ggcaaaggac
    10261 gcggcgttca tctgccagcg tttgatgact tctggaataa caaagagtac gtcgagtttg
    10321 accatccgca gatgtttgtt cgccaccagg cattccgcga agatccggat ctcgaaccgc
    10381 tgggcacgcc gagtggcctg attgagatct actcgaaaac tatcgccgat atgaactacg
    10441 acgattgtca ggggcatccg atgtggtttg agaaaatcga acgctcccac ggtgggcctg
    10501 gctcgcaaaa gtatccgttg catctgcaat ctgtgcatcc ggatttccga cttcactcgc
    10561 agttatgtga gtcggaaacg ctgcgtcagc aatatacggt agcgggtaaa gagccagtat
    10621 tcattaaccc gcaggatgcc agcgcgcgcg gtattcgtaa cggtgatgtg gtacgcgtct
    10681 ttaacgctcg cggtcaggtg ttggcagggg cagtggtttc tgaccgctat gcacccggcg
    10741 tggcacgaat tcacgaaggg gcatggtacg atccagataa aggcggcgag cctggtgcgc
    10801 tgtgcaaata cggtaacccc aacgtgttga ccatcgacat cggtacatcg cagctggcgc
    10861 aggcgaccag tgcgcacact acgctggtgg aaattgagaa gtacaacgga acagtggagc
    10921 aggtgacggc gtttaacggc cccgtggaga tggtggcgca gtgcgaatat gttcccgcgt
    10981 cgcaggtgaa atcatgacca cgctgacagc acaacagatt gcctgtgttt acgcctggct
    11041 agcgcagttg ttctcccgtg agctggacga tgaacaactg acgcaaatcg ccagtgcgca
    11101 gatggctgaa tggttttcgt tgctgaaaag cgaaccgccg ctcactgcgg cggtgaacga
    11161 gctggaaaac cgtattgcca cgctgacagt acgtgacgat gcccgtctgg aactggccgc
    11221 ggacttttgc ggcctgtttc tgatgaccga caaacaagcg gcgctgccgt atgcatcggc
    11281 ctacaaacag gacgagcaag agattaaacg cttgttagtt gaggcaggga tggaaaccag
    11341 cggcaatttc aacgaaccgg cagatcatct ggcgatctat ctcgaattgc tcagccatct
    11401 gcatttttcg ctgggagagg ggaccgttcc tgcgcgaaga atcgacagtt tgcggcaaaa
    11461 aacactgacg gcactgtggc aatggttacc agagtttgtt gcgcgttgtc gtcagtatga
    11521 cagctttggt ttttacgcgg cactaagcca gttattgctg gtgttagtgg agtgcgacca
    11581 ccaaaacaga taacgtcgtt tgtgcgcctg aaaagacgcg tttagcgtcg catcaggcat
    11641 tatggcgcag ttgccggatg cggcgtgaac gtcttatccg gcccacagga actgtaatct
    11701 ttgtagaccg gttaagatgc gtcatcgcat ccggcaaaca cacatcacgg atgagctaca
    11761 aaccgggaaa gccgctggcg cagcaggcgg ttttcctgct tcaggtgcgc aatatcatcc
    11821 attaacgtca gcgccaccgc gatccccggc cagtccagag ccagttcatg acgcaggcgt
    11881 accgcgcgtt gcaccacaat ggcggcatgg tcgtcaaata cccaggttgt ttcctggatc
    11941 tcacgcggtt caaccacccc caaaccgaca atttcattca actcctcttc agagatgccg
    12001 gtatgcaggc aaaattcggt aatagtaaaa gtcaccgtaa cattagccat tatgctttcc
    12061 cccaatcttt acgtggatca aaagacgact gggcgtctgc cagttgctgc cacagcgcgg
    12121 cagtgttttc atccggtttc ggcggcatca cgattttcag taccgcatac agatcgccgg
    12181 tctgtttttt gctcaccaga cctttgcctt taacgcgcaa tcgttgcccg gcctggctgc
    12241 ctggcgggat agtcagcaaa atgctttctt tcagtgttgg aacggtgact ttagcaccca
    12301 gcgccgcttc ccacgggcta accggcacca caatttccag atcctggccg acaatatcaa
    12361 acagcggatg tggcgcaata tgaatcacca gccacaaatc gccatttgga ccgccgtttt
    12421 cgcccggcgt cccctggcct ttcagacgga tgcgttgacc attgccgacg cccgccggga
    12481 tcttcacatt cagcgttttc ggaatttcct gttcgatcat gccaaaggcg ttataaaccg
    12541 gcaggttata gctgatggta cgcttatgct cagtaagcgt ttcttcgagg aataccgcca
    12601 cttcgatttc aatatcgtgg ccgcgtgtgg cggggcgttg acggctctgg cgggcatgct
    12661 gaccgaaaat tgacgagaag atatcgtcaa aatcttcggc gttaaaactc tgaccgtcgc
    12721 catggtggaa ctgacggtta aattgcggat cgttgcgatg ttgccacatc tgatcatact
    12781 cagcgcgacg ttgttcatca cttaacactt cccaggcttc agcgacctct ttgaagcggg
    12841 cttcggcatc cggttctttg ctgacatcag gatggtattt gcgggcaagt cgacgatagg
    12901 cggtcttgat tgtcttgaga tcgtccgtcg gtttcacgcc catgatggcg taataatcct
    12961 ttaattccat agcgttatct cgcgtaaatc aacacaaatt gaaggaaccc ctgtaaggta
    13021 actcctataa gtgtagggta atcctcaaaa tttcatatgc caacacagaa tatgttattg
    13081 aaatcatcgc ggagaggagg tcgccatcaa gatgggttgc tgaacatatt ttaaacaggt
    13141 gaaaaagggt gagcgatttt tgatagttga accaggcact ttaagtttaa ctagggcgtc
    13201 attatttatt aaat
//
LOCUS       DAPHKZ010000125        13174 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.125, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000125 DAPHKZ010000000
VERSION     DAPHKZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13174
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.125"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            120..1619
                     /gene="pitB"
                     /locus_tag="RH288_003714"
     CDS             120..1619
                     /gene="pitB"
                     /locus_tag="RH288_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitB"
                     /protein_id="HDV4032728.1"
                     /translation="MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVAAVIY
                     TRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSTHGLAMVFSMLL
                     AAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
                     VSPIVGLVIAGGLIFLLRRYWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSA
                     AGVAFSHGANDGQKGIGLVMLVLVGIAPAGFVVNMNASGYEITRTRDAVTNFEHYLQQ
                     HPELPQKLIAMEPPLPAASTDGTQVTEFHCHPANTFDAIARVKTMLPGNMESYEPLSV
                     SQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVAMTIGEKIGKRGMTYAQGMAAQMTAAVSIGLASYIGMPVSTTHVL
                     SSAVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIFLSGGLYWIALQLI"
     gene            complement(1668..2360)
                     /locus_tag="RH288_003715"
     CDS             complement(1668..2360)
                     /locus_tag="RH288_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDV4032729.1"
                     /translation="MQSITPPLIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQ
                     AGNVGRAVTKLPLMGKSLHKTIERNQVKTAKKLPGPVPALVITAFVARRLLRFRHMLA
                     CRRRGLIVLTDRYPQDQIPGAYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDL
                     VIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEK
                     AITDFMTARGYH"
     gene            2534..3247
                     /locus_tag="RH288_003716"
     CDS             2534..3247
                     /locus_tag="RH288_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDV4032730.1"
                     /translation="MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPT
                     EHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSC
                     WWAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELK
                     LYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGR
                     HPADEILQASLRAIHAALS"
     gene            3279..4037
                     /locus_tag="RH288_003717"
     CDS             3279..4037
                     /locus_tag="RH288_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032731.1"
                     /translation="MDALQTQTVNSTTAPQPNYIPGLIAVVGCDGTGKSTLTTDLVKS
                     LQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLAAKSSKTQSMKTKSPALWAAV
                     IMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFYYDGPGIGVERATGKISMF
                     LAQRERRLYQQMAQYRPELIIRLGIDIETAISRKPDHDYAELQDKIGVMSKIGYNGTK
                     ILEIDSRAPYSEVLEQAQKAVSLVAIVSDRRSLT"
     gene            4083..5432
                     /locus_tag="RH288_003718"
     CDS             4083..5432
                     /locus_tag="RH288_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDV4032732.1"
                     /translation="MAGFNIKHWFADGAFRTIIRNSAWLGSSNVVSALLGLLALSCAG
                     KGMTPAMFGVLVIVQSYAKSISDFIKFQTWQLVVQYGTPALTNNNPQQFRNVVSFSFS
                     LDIVSGAVAIVGGIALLPFLSHSLGLDDQSFWLAALYCTLIPSMASSTPTGILRAVDR
                     FDLIAVQQATKPFLRAAGSVVAWYFDFGFAGFVIAWYVSNLVGGTMYWWFAARELRRR
                     NIHNAFKLNLFESARHIKGAWSFVWSTNIAHSIWSARNSCSTVLVGIVLGPAAAGLFK
                     IAMTFFDAAGTPAGLLGKSFYPEVMRLDPRTTRPWLLGVKSGLLAGGIGILVALAVLI
                     VGKPLISLVFGVKYLEAYDLIQVMLGAIVISMLGFPQESLLLMAGKQRAFLVAQTIAS
                     IGYIVLLFMFCHLFGVLGAAFAYFGGQCLDVALSLIPTLKAFFQRHSLLYNAAGEKS"
     gene            5432..6256
                     /locus_tag="RH288_003719"
     CDS             5432..6256
                     /locus_tag="RH288_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032733.1"
                     /translation="MMRKYFPLEASERLFVAIEEDDVVDAQVSLPPTIALSCTTEIIH
                     DNYALCLQFWLNGVDRQELLRLVRKQAKGDELTADERKQFKYMRARYKHLRFAQRLYL
                     KKHQAGFLFGKTTVFLGRFQDGFRNGKKNIVSYYGNLLRIYLSSPVWSLVNYSLRHSQ
                     LESVSSFIAYRQKQMHTLKEIIAKPRLTGREFHDVRKIISQQVSYYDTLRSLDPENKE
                     ALQISRFLAAINGLMGDKHDDMVADDMENRQSYDAPVALDSDIRQRLELLISRFPL"
     gene            6268..6828
                     /locus_tag="RH288_003720"
     CDS             6268..6828
                     /locus_tag="RH288_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HDV4032734.1"
                     /translation="MSSRLIIALIIMLLAPGVQAHNFVTGKTVTPVYIQEGGELLLNS
                     DDEIHYQKWNSTQLAGKVRIIQYIAGRKSAKKKNSLLIKAVEAANFPQDRFQPTTIVN
                     TDDAIFGTGYFVVGKIEKNKRRYPWAQFVIDGNGQGRVAWRLPEQSSTILVLNKAGQI
                     QWAKDGSLTPEEVDHVIALAQKLINE"
     gene            6859..7929
                     /gene="lptF"
                     /locus_tag="RH288_003721"
     CDS             6859..7929
                     /gene="lptF"
                     /locus_tag="RH288_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HDV4032735.1"
                     /translation="MKLVEHYIMRGTRRLVLIIVGFLIFIFASYSAQRYLTEAANGTL
                     ALDVVLDIVFYKVLIALEMLLPVGLYVSVGVTLGQMYTDSEITAISAAGGSPGRLYKA
                     VLYLAIPLSIFVTLLSMYGRPWAYAQIYQLEQQSQSELDVRQLRAKKFNTNDNGRMIL
                     SQTVDQDNNRLTDALIYTSTANRTRIFRVRSVDVVDPSPEKPTVMLHNGTAYLIDHQG
                     RDDNEQIYRNLQLHLNPLDQSPNVKRKAKSVTELARSVFPADHAELQWRQSRGLTALL
                     MALLAISLSRVKPRQGRFSTLLPLTLLFIAIFYGGDVCRTLVANGAIPLIPGLWLVPG
                     LMLMGLLMLVARDFSLLQKFSR"
     gene            7926..9005
                     /gene="lptG"
                     /locus_tag="RH288_003722"
     CDS             7926..9005
                     /gene="lptG"
                     /locus_tag="RH288_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HDV4032736.1"
                     /translation="MNVFSRYLIRHLFLGFAAAAGLLLPLFTTFNLINELDDVSPGGY
                     RWTQAVLVVLMTLPRTLVELSPFIALLGGIVGLGQLSKNSELTAIRSMGFSIFRIALV
                     ALVAGILWTVSLGAIDEWVASPLQQQALQIKSTATALGEDDDITGNMLWARRGNEFVT
                     VKSLNEQGQPVGVEIFHYRDDLSLESYIYARSATIEDDKTWILHGVNHKKWLNGKETL
                     ETLDNLAWQSAFTSMDLEELSMPGNTFSVRQLNHYIHYLQETGQPSSEYRLALWEKLG
                     QPILTLAMILLAVPFTFSAPRSPGMGSRLAVGVIVGLLTWISYQIMVNLGLLFALSAP
                     VTALGLPIAFVLVALSLVYWYDRQH"
     gene            complement(9040..10212)
                     /locus_tag="RH288_003723"
     CDS             complement(9040..10212)
                     /locus_tag="RH288_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDV4032737.1"
                     /translation="MGLYDKYARLAGERLQFSDNGLTPFGTCIDEVYSATEGRIGNKK
                     VILAGTNNYLGLTFNHDAISEGQAALAAQGTGTTGSRMANGSYAPHLALEKEIAEFFN
                     RPTAIVFSTGYTANLGVISALADHNAVVLLDADSHASIYDACSLGGAEIIRFRHNDAK
                     DLERRMVRLGERAKEAIIIVEGIYSMLGDVAPLAEIVDIKRRLGGYLIVDEAHSFGVL
                     GATGRGLAEAVGVEDDVDIIVGTFSKSLASIGGFAVGSEAMEVLRYGSRPYIFTASPS
                     PSCIATVRSSLRTIATQPELRQKLMDNANHLYDGLQKLGYELSSHISPVVPVIIGSKE
                     DGLRIWRELISLGVYVNLILPPAAPAGITLLRCSVNAAHSREQIDAIIQAFATLKQ"
     gene            complement(10212..10460)
                     /locus_tag="RH288_003724"
     CDS             complement(10212..10460)
                     /locus_tag="RH288_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDV4032738.1"
                     /translation="MVNREIVMDYILSCLQDLVENGVEIKPDSDLVNDLGLESIKVMD
                     LLMMLEDRFDISIPINILLDVKTPAQLMETLLPWLENK"
     gene            complement(10492..11406)
                     /locus_tag="RH288_003725"
     CDS             complement(10492..11406)
                     /locus_tag="RH288_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001481799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDV4032739.1"
                     /translation="MNQTVAVTGATGFIGKYIIDNLLARGFHVRALTRTARAHVNDNL
                     TWVRGSLEDTHSLSELVAGASVVVHCAGQVRGHKEEIFTRCNVDGSLRLMQAAKESGF
                     CQRFLFISSLAARHPELSWYAKSKYVAEQRLAAMADEITLGVFRPTAVYGPGDKELKP
                     LFDWMLRGLLPRLGAPDTQLSFLHVTDFAQAVGQWLSAETIQTQTYELCDGVVGGYDW
                     QRVQQLAADARCGSVRMVGIPLPVLTGLADISTALSRLAGKEPMLTRSKIRELTHADW
                     SASNNRISEDINWFPGISLEHALRNGLF"
     gene            complement(11403..13133)
                     /locus_tag="RH288_003726"
     CDS             complement(11403..13133)
                     /locus_tag="RH288_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acyl-AMP ligase"
                     /protein_id="HDV4032740.1"
                     /translation="MVYMSNKIFTHSLPMRYADFPTLVDALDYAALSSAGMNFYDRRC
                     QLEDQLEYQTLKARAEAGAKRLLSLNLKKGDRVALIAETSSEFVEAFFACQYAGLVAV
                     PLAIPMGVGQRDSWSAKLQGLLASCQPAAIITGDEWLPLVNAATHDNPELHVLSHAWF
                     KALPEADVALQRPVPNDIAYLQYTSGSTRFPRGVIITHREVMANLRAISHDGIKLRPG
                     DRCVSWLPFYHDMGLVGFLLTPVATQLSVDYLRTQDFAMRPLQWLKLISKNRGTVSVA
                     PPFGYELCQRRVNEKDLAELDLSCWRVAGIGAEPISAEQLHQFAECFRQVNFDNKTFM
                     PCYGLAENALAVSFSDEASGVVVNEVDRDILEYQGKAVAPGAETRAVSTFVNCGKALP
                     EHGIEIRNEAGMPVAERVVGHICISGPSLMSGYFGDQVSQDEIAATGWLDTGDLGYLL
                     DGYLYVTGRIKDLIIIRGRNIWPQDIEYIAEQEPEIHSGDAIAFVTAQEKIILQIQCR
                     ISDEERRGQLIHALAARIQSEFGVTAAIDLLPPHSIPRTSSGKPARAEAKKRYQKAYA
                     ASLNVQESLA"
BASE COUNT         3171 a         3268 c         3411 g         3324 t
ORIGIN      
        1 ctgatacaca agaaataaca ctctttttat cgttaaaaaa tgatatttca ctttgcccat
       61 gccgttaaag tcactgataa tgcgtccgtt cgtaaattca aaatggcgta atctaatata
      121 tgctaaattt atttgttggc cttgatatat acacagggct tttgttattg cttgctctgg
      181 catttgtgtt gttctacgaa gcaatcaatg gttttcatga cacggcgaat gcggtggcag
      241 ccgttattta tactcgtgcc atgcaaccac aacttgctgt ggtgatggcg gcatttttta
      301 acttttttgg cgtgttattg ggcggactta gcgttgccta tgccattgtc catatgttgc
      361 caaccgattt gttgctgaat atggggtcaa cccacggcct ggcgatggtc ttttccatgc
      421 tgctggcggc gattatctgg aacctgggaa cgtggttctt cggtttaccg gcctccagtt
      481 cgcacacctt gattggtgcg attatcggca tcggtttaac caacgcgctg ttaaccggct
      541 catcggtgat ggatgcgtta aacctgcgtg aagtgaccaa aattttctcc tcgctgattg
      601 tttcccctat cgtcggcctg gtcattgcgg gaggcctgat attcctgctg cgacgctact
      661 ggagcgggac gaaaaagcgt gaccgtattc accgcattcc ggaagatcgc aaaaagaaaa
      721 aaggcaaacg taaaccgcca ttctggacgc gtattgcgct gattgtttcc gctgcgggcg
      781 tggcgttttc gcacggcgcg aacgacggac aaaaagggat cggcctggta atgctggtac
      841 tggtggggat tgcccctgct ggcttcgtcg tcaatatgaa tgcgtccggc tatgaaatta
      901 cccgtacccg cgatgccgtt accaacttcg aacactacct gcaacagcat cctgaactgc
      961 cgcagaagtt gattgcgatg gaacctccat tgcctgcagc atcgactgat ggcacgcaag
     1021 taacagagtt tcactgtcat ccggcaaata cctttgatgc tattgcgcgc gttaaaacga
     1081 tgctgccagg caatatggaa agttacgagc cgttaagcgt gagtcagcgc agccagctgc
     1141 gccgcattat gctgtgcatc tctgatacct ccgcgaagct agcgaaactg ccaggcgtca
     1201 gtaaagaaga ccagaacctg ctgaaaaaac ttcgcagcga tatgttaagc accattgagt
     1261 acgctccggt gtggatcatc atggcggtag cactggcgct cggcattggc accatgattg
     1321 gctggcgtcg tgtagcgatg accatcggtg agaagattgg taagcgcggc atgacgtatg
     1381 cgcaaggcat ggcggcacaa atgacggcgg cagtgtctat cggtcttgcc agttatattg
     1441 ggatgcccgt ctccacaaca cacgtcctct cgtctgcagt tgcagggacg atggtggtgg
     1501 acggcggtgg gttacagcgt aaaacggtaa ccagcatcct gatggcgtgg gtatttactt
     1561 taccggcggc aatttttctt tctggtgggc tgtactggat agcattgcag ttgatttaac
     1621 cttcctgaaa atgcccggtc ctggcgatcg ggcatttcca tttttgacta gtgataacca
     1681 cgcgcggtca taaaatccgt aatcgctttt tctgcatcaa ccaacacctg ttccagtggc
     1741 tgattggcat cgatatcaac cagttgtgca ccaccaaagg ttaactgtgg cgttatggca
     1801 atcttcctcg ccagcgattc ccgtttatgg tcgggtttac gtgcacaggc aacttcaagg
     1861 tcaacattga gtttgatgac cagatcaggc ttatggctcg ccatccagtg aaacgcttta
     1921 cgttcctggc ttgccagcca tgagacaaaa cgaccacctt caacgttagg tgggaacacc
     1981 gtaccatcgt aagcgccagg aatttggtcc tgaggataac ggtcggttag aacaattaac
     2041 ccgcgacgac gacaggcaag catatgacga aagcgcagta agcgacgggc gacaaacgct
     2101 gtaattacca gcgccggaac tggtccaggc aatttttttg ctgttttcac ctgatttcgt
     2161 tcaattgttt tatgtaagga ttttcccatc aacggtaatt ttgtcactgc acgaccgaca
     2221 tttccggcct gttttcctaa atgaactctt tcggcagcac catatttttc gacaacggta
     2281 ataagatgtt cacacaccgt tgacttgcct gaaccatcgc taccaataac ggcaattaat
     2341 ggaggtgtta ttgactgcat gaatatatcc tttaatttaa atatccatta aaaatattta
     2401 tttggttaat atgtttttat gaaagcgtaa ttcaggtcaa tgtcacaatt aaccattgtc
     2461 acaataaggt tgaacggata ttctgagcac ggaccacgta atattcaata cattatttac
     2521 tgccgggttt ttcgtgaatc aacgtaatat gtcaataatt aattccacgc cagtgcgtgt
     2581 tattgccatt gtaggatgtg atggttcagg taaatcgacc ctcacggcaa gcctggtaaa
     2641 tgaactggca gcaagaatgc caacagaaca catttatctc gggcaatcgt ccgggcgaat
     2701 tggcgaatgg atttcacagc tccctgttat tggcgcacct tttgggcgtt atctgcgaag
     2761 taaagcggca catgtgcacg aaaagccctc aacaccgcct ggcaatatta ctgcactggt
     2821 tatctatctg ctttcctgct ggtgggcgta caagtttcgc aaaatgttgt gtaaaagcca
     2881 gcaaggcttt ctgctcatca ccgaccgcta cccgcaggtt gaagtgccgg ggtttcgctt
     2941 tgatggcccg caattggcaa aaaccacggg cggtaacggt tggataaaaa tgttaaggca
     3001 gcgcgagctg aagctgtacc aatggatggc atcttatttg cccgtattgt tgattcgtct
     3061 tggcattgat gaacaaaccg cgtttgcgcg taaacctgac caccaactgg cagcgttaca
     3121 ggaaaaaatc gccgttacgc cgcaactgac attcaatggc gcaaagatcc ttgaactgga
     3181 tgggcgacac cccgccgatg aaattctgca agcgtcacta cgcgcaattc acgccgcgct
     3241 ttcctgatca ccaaaatgga taggggatga tttaacgaat ggatgcacta caaactcaaa
     3301 ctgttaatag tacaaccgcg ccgcagccca actacattcc ggggctgatt gcggtggtcg
     3361 ggtgtgatgg caccggtaaa tccacactga ccaccgacct ggtgaaatcg ctgcaacaac
     3421 actggcaaac cgagcggcgc tatctggggc tgctctccgg cgaagacggc gacaaaatca
     3481 aacgattgcc gttggttggc gtctggctgg aacggcgact ggcggccaaa tcctcgaaaa
     3541 cccaaagcat gaaaaccaaa tctccggcgc tatgggcggc ggtgattatg tactgcttct
     3601 cgctgcgaag aatggcgaat ctacgcaagg ttcagcgact ggcgcaaagt ggcgttctgg
     3661 tggtcagcga tcgcttcccg caggctgaaa tttcgggctt ttattatgat ggaccgggga
     3721 ttggcgtcga acgtgcgacc gggaaaatca gcatgtttct ggcgcagcgc gaacggcgtt
     3781 tataccaaca aatggcgcaa tatcgcccgg aattaattat tcgcctgggc attgatattg
     3841 agactgccat ctcccgcaag cctgaccatg actatgccga gctgcaggac aaaatcggtg
     3901 tcatgtcgaa gattggctat aacggcacaa aaattcttga gattgattcc agagcgccct
     3961 acagcgaagt gctggaacag gcacagaagg cggtttctct ggttgccatc gtttctgacc
     4021 gccgaagttt aacttaaggc tggcgggata ctttttacta tcaacgataa ggtcaggctg
     4081 aattggcggg ttttaacatc aaacattggt ttgcagatgg cgcgtttcgc accattattc
     4141 gcaatagcgc ctggttaggc tccagtaatg tcgtgagcgc cttgctgggt ctgttggcgc
     4201 tctcgtgtgc cggtaaaggg atgacgcccg ccatgtttgg cgtactggtg attgtgcaat
     4261 cgtacgccaa gtcgatcagc gattttatta agtttcagac atggcaactg gtggttcagt
     4321 acggaacacc agcattaacc aacaataatc cgcagcaatt ccgcaatgtc gtctcatttt
     4381 ccttctcgct ggatatcgtc agcggcgcgg tggcgattgt cggtggcatt gccttactgc
     4441 cattcctttc ccattcatta ggtctggatg accaaagttt ttggctggca gcgctctatt
     4501 gcacgctcat tccttcaatg gcttcctcca cgccgaccgg cattctgcgt gcggtagatc
     4561 gcttcgattt aattgctgta cagcaggcga cgaaaccttt tctgcgcgca gcggggagcg
     4621 tcgtagcctg gtattttgac tttggttttg cgggttttgt tattgcctgg tacgtgtcga
     4681 atctggttgg cggcaccatg tactggtggt ttgccgcgcg cgaattacgc cgccgaaata
     4741 tccataacgc cttcaaattg aatctgtttg agtctgcccg acacattaaa ggcgcgtgga
     4801 gttttgtctg gtcaaccaac attgcccact ccatctggtc ggcgcgtaac tcgtgcagca
     4861 cagtgttggt ggggatcgtg ttaggacccg ctgccgccgg gttatttaaa atcgccatga
     4921 cattcttcga cgccgccgga acgccagcgg gtttgctggg taaaagtttt tacccagagg
     4981 tgatgcgttt agatccgcgc accaccagac cgtggttgtt aggtgtgaag tccggtttac
     5041 tggcgggcgg aatcggtatt ctggtggcgc tcgcggtgtt gatcgtcggc aagccgctca
     5101 tttcgctggt gtttggcgtt aagtatctcg aagcgtatga cctgattcag gtgatgctgg
     5161 gcgcaattgt gatttcgatg ctgggcttcc ctcaggagtc attgctattg atggcgggaa
     5221 aacagcgcgc ttttctcgtg gcgcaaacca tcgcctcaat cggctacatc gtattgctgt
     5281 tcatgttctg tcatctgttt ggtgtgctgg gagcagcgtt tgcttacttc ggtgggcaat
     5341 gtctggacgt ggcgctctcg ttaattccaa ccttaaaggc attttttcag cgccattcct
     5401 tgctttataa cgcagccgga gagaaatcct gatgatgaga aaatatttcc cgcttgaggc
     5461 gagcgagcgt ctatttgttg cgattgaaga agatgatgtc gttgatgcac aggttagttt
     5521 gccgccgact attgcactaa gttgtaccac cgaaatcatt catgataatt acgcgttatg
     5581 cctgcaattc tggctcaatg gcgttgatcg tcaggagtta ctgcgtttag ttcgcaaaca
     5641 agccaaaggc gatgagctga ctgctgatga gcgcaaacaa tttaaataca tgcgagcgcg
     5701 ctacaagcac ctgcgttttg cgcaacggct gtatttaaag aagcatcagg ccggattttt
     5761 attcggcaaa acgaccgttt ttctggggcg ttttcaggac ggctttcgta acggtaagaa
     5821 aaatattgtg tcgtattacg gcaacctgtt acggatttat ttaagctctc cggtctggtc
     5881 gttggtgaac tattcattac gccatagcca gttagaaagc gtaagcagtt ttattgccta
     5941 tcggcaaaag caaatgcata ccctgaaaga gattattgcc aaaccgcgac taaccggtag
     6001 ggaatttcat gatgtgcgaa aaatcatcag ccagcaggtt tcttattacg acaccttaag
     6061 atcgcttgat cctgaaaata aagaggcgtt acagatatcc cgcttcctcg ccgccattaa
     6121 tggcctgatg ggagataaac acgacgacat ggtggcggat gatatggaaa accgccagtc
     6181 gtatgatgca ccggtggcgc tggatagcga tattcgtcag cgcttagagc tgctgatttc
     6241 gcgttttccg ctatagccgg agcaatgatg tcatctcgtt tgattattgc gttgattatc
     6301 atgctcttag ccccgggtgt gcaggcacac aatttcgtca ctggcaaaac ggttacccct
     6361 gtttatatcc aggaaggcgg cgagctgctt ctgaatagcg acgacgaaat tcactaccaa
     6421 aagtggaaca gcacacaatt agcgggaaaa gtccgcatta ttcagtatat cgccgggcgt
     6481 aagtcggcga agaaaaagaa ctcactgtta attaaagcgg ttgaagcggc aaactttccg
     6541 caggatcgtt ttcagcccac caccattgtg aacaccgatg atgccatctt tggtactggc
     6601 tattttgttg ttggcaaaat cgaaaaaaat aaacgccgct atccgtgggc gcaattcgtt
     6661 attgacggca atggacaggg acgcgttgcc tggcgcttgc cggagcagag ttcaaccatt
     6721 ctggtgctga ataaagccgg gcaaattcag tgggcaaagg acggcagcct gacgccggaa
     6781 gaggtagatc atgtcattgc gttggcgcag aaactgatca atgaataaaa aactcaaagg
     6841 attgagggcg ttagtgagat gaagctggtt gaacactaca tcatgcgtgg tacgcgccgt
     6901 ctggtgctga ttatcgtcgg ttttctgatc tttattttcg ccagctactc cgcacagcgt
     6961 tatctgaccg aagcggcaaa tgggacatta gctcttgatg ttgtgctgga tatcgttttc
     7021 tacaaagtac tgattgcact ggagatgttg ttacctgttg gtctgtatgt gtcagttggc
     7081 gtgacgctag ggcagatgta taccgactcg gaaattaccg ctatctctgc ggcggggggc
     7141 agtccgggac gcttgtacaa agccgttctt tatctggcga taccgctaag tatttttgtc
     7201 acccttctgt cgatgtatgg tcgtccgtgg gcttatgcgc agatttatca actggagcag
     7261 cagtcgcagt cggagctgga tgttcgccag ttgcgggcaa agaaatttaa cactaacgat
     7321 aacggacgaa tgatcctttc gcagacggtt gatcaggata ataatcgcct gactgacgcg
     7381 ctgatttata cttctactgc caatcgaacc cgcattttcc gcgtccgttc ggttgatgtg
     7441 gttgacccat cacccgagaa accgaccgtt atgttgcaca acggcactgc ctatcttatc
     7501 gatcatcagg ggcgtgatga caacgaacag atctaccgta atctgcaatt acatctgaat
     7561 ccgctggatc aaagccctaa cgtcaaacgc aaagcgaaat cggtcacgga gctggcgcgc
     7621 tccgtctttc cagccgatca tgccgaactg caatggcggc aaagccgtgg cctgaccgca
     7681 ttgttgatgg cgctgctggc catttcatta agtcgggtaa aaccgcgtca agggcgattt
     7741 tcaacgttat tgccactgac gttgctgttt attgccattt tttatggcgg tgacgtctgc
     7801 cgtacgctgg tggctaacgg cgcgattccc ctcattcctg gtttgtggtt agtacccgga
     7861 ctcatgctaa tgggcctgct gatgctggtc gcacgcgact tctctttgct gcagaaattt
     7921 tcccgatgaa tgttttcagc cgctatttaa tccgtcatct ctttctcggt tttgccgccg
     7981 ccgcagggct attgctgccg ctttttacca ccttcaacct gattaacgaa ctggatgatg
     8041 tcagcccggg cggttatcgc tggactcagg cggtgctggt ggtgctaatg accttaccgc
     8101 gcacactggt cgaactttcg ccatttatcg ccttattggg agggattgtc ggcctggggc
     8161 agttatcgaa aaacagtgag cttaccgcca ttcgcagcat ggggttttct atcttccgta
     8221 ttgcactggt ggcgctggtt gcagggatat tgtggactgt ttcgttaggc gcgatagatg
     8281 agtgggtagc gtcgccatta cagcaacagg cgttgcaaat caaatcgacc gccaccgcgt
     8341 tgggggagga cgatgacatt accggcaata tgctgtgggc caggcgtggt aatgaatttg
     8401 tgacggtgaa atcgctgaac gagcagggcc agccggtggg cgtggagatt tttcattatc
     8461 gcgacgatct ctcgctcgaa tcctacattt atgcacgcag tgccaccatt gaagacgaca
     8521 aaacgtggat cctgcatggt gtgaatcata aaaaatggct gaatggcaaa gaaacgctgg
     8581 aaacattaga taatcttgcc tggcaatcgg ccttcaccag tatggatctt gaagagttat
     8641 caatgccggg caatactttt tctgtccgtc agcttaatca ttacatccat tatttgcagg
     8701 aaaccgggca acccagcagc gaataccgcc ttgcactgtg ggaaaaactg gggcaaccca
     8761 tcctgaccct ggcgatgatt ttgctggctg tgccgtttac ctttagcgcc ccgcgctcgc
     8821 cagggatggg tagccgtctc gctgtaggtg tcatcgttgg cttactcacc tggatcagct
     8881 atcaaatcat ggtcaatctg ggattgctat ttgcgttgag cgcacctgtt accgcgctcg
     8941 gtttaccgat agcgtttgtg ctggtggcgt tgagcctggt gtattggtat gacagacaac
     9001 attaaacccg ccgtggcgca acaccacggc gggctcacat tactgcttca gagtagcaaa
     9061 tgcctgaatg atggcatcga tttgctcacg actgtgagca gcgtttacgc tacagcgcag
     9121 cagcgtgatg cctgcaggcg cggcaggtgg caggataaga ttcacataaa cgcccagcga
     9181 aataagctcg cgccagatgc gtaaaccgtc ctctttcgaa ccgattatta ccggcactac
     9241 cgggctaata tgtgaactta actcataacc cagtttttgc agaccgtcat acagatggtt
     9301 ggcattatcc atcagctttt gccgcagctc tggttgtgtg gcaatagttc ttaacgacga
     9361 gcgcacggtc gcaatgcagg acggagaagg agaggcggta aaaatatacg ggcggctgcc
     9421 gtagcgcagc acttccatcg cttccgaacc gacagcaaaa ccgccaatcg aggccagact
     9481 tttactgaag gtgccaacga taatatccac atcatcttca acgccgacag cttcagccag
     9541 tccgcgcccc gttgcgccta acacgccaaa cgaatgcgct tcatcgacaa tcaaataacc
     9601 accgagacga cgtttgatat caacaatttc cgctaacggc gcaacgtcac cgagcatgct
     9661 gtagataccc tcaacgatga taatcgcctc tttcgcccgt tcaccgaggc gaaccatgcg
     9721 ccgttccaga tctttagcat cgttatggcg gaaacgaata atttccgcgc caccgagaga
     9781 acaggcgtca taaatactgg cgtggctgtc ggcatccagt aacaccacgg cgttatggtc
     9841 ggcaagtgcg ctgatgacgc ctaaattagc ggtataaccg gttgaaaaaa cgatagcggt
     9901 agggcgattg aaaaactcgg caatctcttt ctctaacgcc aggtgcggcg cataactgcc
     9961 gtttgccata cgagaaccgg tggtgccggt accttgggcc gctaacgcgg cctgaccttc
    10021 gctgatggca tcatgattaa aggttaaacc gagataatta ttggtcccgg ccagaatcac
    10081 ttttttattg ccgatccggc cttcggtggc ggaatacact tcatcaatac aggtgccaaa
    10141 cggtgttaac ccgttgtcac taaattgcag tcgctcgcca gcaaggcgcg catatttatc
    10201 gtatagcccc attatttatt ctccagccat ggaagtagag tttccattaa ttgcgcaggg
    10261 gttttgacat ccagcagaat attaatagga atggaaatat cgaatctgtc ttccagcatc
    10321 attaagagat ccatcacttt gatcgactcc aggccaagat cgttgacgag atcgctgtcg
    10381 ggcttaattt ccacaccgtt ttcgaccaaa tcctgtaaac aggaaaggat gtaatccatt
    10441 actatttcac gatttaccat agaaacgtta acacaccttt aaacaagaca atcaaaatag
    10501 cccgttgcgt aatgcgtgtt ccaggctaat cccgggaaac caattaatat cttcagaaat
    10561 acggttatta cttgccgacc agtcggcgtg ggttaattca cgaattttcg agcgggtcag
    10621 cataggttct ttacctgcca ggcgactcaa cgcggtactg atatccgcaa ggccggtgag
    10681 taccggcaga ggaatgccaa ccattcgcac ggaaccgcaa cgggcgtcgg cggcaagttg
    10741 ctgtacgcgt tgccagtcat agccgccgac gacgccatcg cataattcat aggtttgcgt
    10801 ctgtatagtt tcggcgctta accactgacc cactgcttgc gcgaaatcgg tgacgtgcag
    10861 aaaagagagc tgtgtatctg gcgcaccaag tcgtggcagc aggccgcgca gcatccagtc
    10921 aaacagcggt tttaactctt tatcgccggg accatacacg gctgtcgggc gaaaaacgcc
    10981 cagcgtaatt tcgtccgcca ttgctgccag tcgttgctcg gcgacgtatt tggattttgc
    11041 ataccaggag agctcgggat ggcgcgccgc cagcgaagag ataaacagaa aacgttggca
    11101 aaagccgctc tcttttgctg cttgcatcag gcgcaggctg ccgtcaacgt tacagcgggt
    11161 gaaaatctct tctttgtgcc cgcgcacttg cccggcgcaa tggaccacta cgctggctcc
    11221 ggcaaccagc tcgctaagtg aatgagtatc ttccagcgaa ccgcgcaccc aggtgagatt
    11281 atcattgacg tgagcgcggg cagtacgcgt caatgcgcga acgtgaaagc cgcgggcgag
    11341 caggttatcg ataatatatt taccgataaa cccggtagcg cccgtcaccg cgacagtttg
    11401 attcatgcca gggattcctg cacattaaga ctggcagcat aagccttctg ataacgtttt
    11461 ttcgcttccg cacgggcagg cttgccggag gacgttcggg gaatactgtg gggcggcaac
    11521 agatcgatag ccgcggtcac gccaaattcg ctttggatcc gtgccgccag cgcgtggata
    11581 agctgcccgc gacgttcttc gtcgctgatc cgacactgga tctgcaaaat gattttttcc
    11641 tgggcggtaa caaaagcaat cgcatcgcca gaatgaattt ccggttcctg ttccgctata
    11701 tattcaatat cctgcggcca gatattacgg ccacgaataa taatcagatc tttaatgcgt
    11761 ccggtgacat acagataacc gtccagcaga taaccgaggt cgccggtgtc taaccagccc
    11821 gtcgcggcaa tctcgtcttg cgaaacctgg tcgccaaagt aaccgctcat cagactggga
    11881 ccggagatgc aaatatggcc taccacacgt tccgcgaccg gcatacctgc ttcattgcgg
    11941 atttcaatac catgttccgg caacgctttg ccgcagttga cgaaagtcga tacggcgcgt
    12001 gtctctgcac ccggcgcgac ggctttaccc tgatattcga ggatgtcgcg atccacttcg
    12061 ttaaccacaa ccccggaggc ttcatcagag aagctgacag ccagcgcatt ttctgccagt
    12121 ccgtagcacg gcatgaaagt tttattgtca aagttaacct gacggaaaca ttcagcgaat
    12181 tgatggagtt gttctgcgga gatgggttct gcaccaatac cagcgacgcg ccagcaggaa
    12241 agatccagtt cagcgagatc tttttcattc acgcggcgct ggcacaattc atagccaaac
    12301 ggcggcgcaa cggaaacggt gccgcgattt ttactgatca atttaagcca ttgcagagga
    12361 cgcatggcaa aatcctgagt gcgcaaataa tctactgaaa gctgcgtggc gacgggggtc
    12421 aggagaaagc cgaccagtcc catatcatgg tagaaaggca gccaggagac gcagcggtcg
    12481 ccagggcgta atttaatgcc gtcgtggctt atagcacgta gattagccat cacttcgcga
    12541 tgggtgataa tgacgccacg gggaaaacgg gtgctgccgg aggtgtactg gaggtaggcg
    12601 atatcgttcg gaactggacg ctggagcgca acatcggctt ccggtaatgc cttaaaccag
    12661 gcgtggctta aaacatgtaa ttcggggttg tcatgcgtcg cggcattgac cagtggcaac
    12721 cactcatcac cagtgataat ggctgcgggc tggcaacttg ccagtaaacc ctgcaatttg
    12781 gcgctccagg aatcccgctg accaacgccc attggaatcg ccaacgggac ggcgactaag
    12841 ccggcatact ggcaggcaaa aaaagcctct acgaactcgc tacttgtttc ggcaatcagt
    12901 gccacgcgat cgcctttttt caggttcagc gataacaacc gcttcgcacc agcttcggca
    12961 cgtgctttta acgtctgata ttccagttga tcttcaagtt ggcaacgtct gtcataaaaa
    13021 ttcattccgg cgctactcag agcggcgtag tccaaagcat caacaagcgt tggaaaatcg
    13081 gcatagcgca taggtaggga atgcgtaaag attttattag acatatacac cacgaaaaaa
    13141 ttggatatcc aaaataaaat gacaataatg cggt
//
LOCUS       DAPHKZ010000126        13065 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.126, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000126 DAPHKZ010000000
VERSION     DAPHKZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13065
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.126"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(226..1875)
                     /gene="pgi"
                     /locus_tag="RH288_003727"
     CDS             complement(226..1875)
                     /gene="pgi"
                     /locus_tag="RH288_003727"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDV4032741.1"
                     /translation="MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSAT
                     FDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALR
                     NRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
                     GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG"
     gene            2400..3749
                     /gene="lysC"
                     /locus_tag="RH288_003728"
     CDS             2400..3749
                     /gene="lysC"
                     /locus_tag="RH288_003728"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HDV4032742.1"
                     /translation="MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAA
                     ALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDIA
                     ALAELAALQLLPRLNEGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVD
                     IWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNDLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHSNLFE"
     gene            4002..4274
                     /locus_tag="RH288_003729"
     CDS             4002..4274
                     /locus_tag="RH288_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HDV4032743.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRVLTNSETNSIKK
                     DYIDKLMVEREAEAKKARQLKKKQAYKPDPEASFSWSANTSTRGRR"
     gene            complement(4407..5279)
                     /gene="rluF"
                     /locus_tag="RH288_003730"
     CDS             complement(4407..5279)
                     /gene="rluF"
                     /locus_tag="RH288_003730"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HDV4032744.1"
                     /translation="MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGD
                     QVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIENSSSEVKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASN
                     GKRFTSPGRKKKGR"
     gene            5491..6180
                     /gene="pepE"
                     /locus_tag="RH288_003731"
     CDS             5491..6180
                     /gene="pepE"
                     /locus_tag="RH288_003731"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HDV4032745.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQ
                     TWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGL
                     LAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTN
                     ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGE
                     EAVPLEAGHRF"
     gene            complement(6271..7902)
                     /locus_tag="RH288_003732"
     CDS             complement(6271..7902)
                     /locus_tag="RH288_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDV4032746.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLSLPKAELVI
                     YFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALAN
                     AARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEE
                     LAEEESRRWAEIIEMSLNLEQASDIVERMGSEIADKSLAARRAFSLDGLKELDALYEQ
                     LLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY"
     gene            complement(8122..11805)
                     /gene="metH"
                     /locus_tag="RH288_003733"
     CDS             complement(8122..11805)
                     /gene="metH"
                     /locus_tag="RH288_003733"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDV4032747.1"
                     /translation="MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFAD
                     WPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAE
                     INFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP
                     EIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     NGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQG
                     KGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKIL
                     TEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRR
                     DDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEA
                     RQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDF
                     AFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLR
                     QQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMV
                     KALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHT
                     EKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYA
                     RRKGMSVTEVERWLAPNLGYDAD"
     gene            12005..12829
                     /gene="iclR"
                     /locus_tag="RH288_003734"
     CDS             12005..12829
                     /gene="iclR"
                     /locus_tag="RH288_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HDV4032748.1"
                     /translation="MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAIGAHAFMVGSSFLQSRNLL
                     AIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
                     AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHAL
                     GLRCLAACIFDEHREPFAAISISGPISRITDDRVTEFGAMVIKAAKEVTLAYGGMR"
BASE COUNT         3014 a         3490 c         3371 g         3190 t
ORIGIN      
        1 ttccgttaaa ttacagacaa ggggatttat ctgataaaaa aatgccgaca taacgtcggc
       61 attgttatta aggttattta atcaatcgtg ctatgtatta attgccgaat acgatgtaca
      121 tatcggcatc gacctgtagg cctgataaga cgcgaccgcg tcgcatcagg catcggttgc
      181 cggatgcggc gtgaacgcct tatccggcct acatatcgac gatgattaac cgcgccacgc
      241 tttatagcgg ttaatcagac cattggtcga gctatcgtgg ctgctgattt ctttatcatc
      301 tttcagctct ggcagaatac ggttcgccag ctgtttaccc agttccacgc cccactggtc
      361 gaaggtgaag atgttcagga tcacgccctg agtaaagatt ttgtgctcat acagcgcaat
      421 caacgcaccc aggctgaacg gagtgatttc acgcagcagg atggagttgg tcgggcggtt
      481 accttcgaat actttgaacg gcaccacgta gtcaagcgtt gccggatctt taccctgatc
      541 acgatattcc tgctcaacca cttcgcggga tttaccaaac gccagcgctt cggtctgggc
      601 gaagaagtta gacagcagtt tctggtgatg atcagagagc gggttatggg tgatagccgg
      661 agcgatgaaa tcgcacggta ccattttggt tccctggtgg atcagctggt agaacgcgtg
      721 ctgaccgtta gtgcctggtt caccccagat aatcgggcca gtctggtaat ccacaacgtt
      781 accgttacgg tcaacatact taccgttgga ctccatattg ccctgctgga agtacgccgc
      841 gaaacggtgc atatactggt catacggcag aatcgcttca gtttccgcac caaagaaatt
      901 gttgtaccag atgccaatca gcgccagcag tacaggcagg tttttctcgg caggcgtggt
      961 ggagaaatgc ttgtccatcg cgtgtgcgcc ggaaagcagt tcaacgaagt tatcaaagcc
     1021 gatggagaga acaatcgaca ggccaatcgc tgaccacaaa gagtaacggc cgccaaccca
     1081 gtcccagaac tcgaacatgt tggcagtatc aataccaaac tcgccaacgg ctttggcatt
     1141 ggtggaaagc gccgcaaagt gttttgcaac gtgtttttca tcacctgccg ctttcaggaa
     1201 ccagtcacgc gcgctatggg cgttggtcat agtttcctga gtggtgaagg ttttagatgc
     1261 taccaggaac agcgtagttt ccgggtttac ttttttcagc acttccgcga tgtgagtccc
     1321 atcgacgtta gaaacaaagt gcatgttcag gtggtttttg tacggacgca gagcttcggt
     1381 caccatgtat gggccgaggt cagaaccgcc gatcccgatg ttcactacgt cagtgattgc
     1441 tttgccggta taacctttcc actcaccgga aataatcgct tctgagaagg ttttcatctt
     1501 ctccagcacc gcgttgactt ccggcattac gtctttgcca tcaaccaaaa tcggggtatt
     1561 gctacggtta cgcagcgcta cgtgcagcac ggcgcggttt tcagtgcggt tgatcttctc
     1621 gccagagaac atcgacttaa tcgcgcccgc cagatcgcac tctttcgcca gatcctgtaa
     1681 tttcgccagc gtctcttcag tgatgcggtt tttggagtaa tccaccagca tctgatcgtc
     1741 gaaggttgcg gagaacttag aaaaacgatc gccgtcttta gcaaaaagat cggcgatcgt
     1801 aacgtctttc atttcatcga agtgtttctg tagtgcctgc caggcagcgg tctgcgttgg
     1861 attgatgttt ttcattagca atactcttct gattttgaga attgtgactt tggaagattg
     1921 tagcgccagt cacagaaaaa tgtgatggtt ttagtgccgt tagcgtaatg ttgagtgtaa
     1981 acccttagcg cagtgaagca tttattagct gaactactga ccgccaggag tggatgaaaa
     2041 atccgcatga ccccatcgtt gacaaccgcc ccgctcaccc tttatttata aatgtactac
     2101 ctgcgctagc gcaggccaga agaggcgcgt tgcccaagta acggtgttgg aggagccagt
     2161 cctgtgataa cacctgaggg ggtgcatcgc cgaggtgatt gaacggctgg ccacgttcat
     2221 catcggctac aggggctgaa tcccctgggt tgtcaccaga agcgttcgca gtcgggcgtt
     2281 tcgcaagtgg tggagcactt ctgggtgaaa atagtagcga agtatcgctc tgcgcccacc
     2341 cgtcttccgc tcttcccttg tgccaaggct gaaaatggat cccctgacac gaggtagtta
     2401 tgtctgaaat tgttgtctcc aaatttggcg gtaccagcgt agctgatttt gacgccatga
     2461 accgcagcgc tgatattgtg ctttctgatg ccaacgtgcg tttagttgtc ctctcggctt
     2521 ctgctggtat cactaatctg ctggtcgctt tagctgaagg actggaacct ggcgagcgat
     2581 tcgaaaaact cgacgctatc cgcaacatcc agtttgccat tctggaacgt ctgcgttacc
     2641 cgaacgttat ccgtgaagag attgaacgtc tgctggagaa cattactgtt ctggcagaag
     2701 cggcggcgct ggcaacgtct ccggcgctga cagatgagct ggtcagccac ggcgagctga
     2761 tgtcgaccct gctgtttgtt gagatcctgc gcgaacgcga tgttcaggca cagtggtttg
     2821 atgtacgtaa agtgatgcgt accaacgacc gatttggtcg tgcagagcca gatatagccg
     2881 cgctggcgga actggccgcg ctgcagctgc tcccacgtct caatgaaggc ttagtgatca
     2941 cccagggatt tatcggtagc gaaaataaag gtcgtacaac gacgcttggc cgtggaggca
     3001 gcgattatac ggcagccttg ctggcggagg ctttacacgc atctcgtgtt gatatctgga
     3061 ccgacgtccc gggcatctac accaccgatc cacgcgtagt ttccgcagca aaacgcattg
     3121 atgaaatcgc gtttgccgaa gcggcagaga tggcaacttt tggtgcaaaa gtactgcatc
     3181 cggcaacgtt gctacccgca gtacgcagcg atatcccggt ctttgtcggc tccagcaaag
     3241 acccacgcgc aggtggtacg ctggtgtgca ataaaactga aaatccgccg ctgttccgcg
     3301 ctctggcgct tcgtcgcaat cagactctgc tcactttgca cagcctgaat atgctgcatt
     3361 ctcgcggttt cctcgcggaa gttttcggca tcctcgcgcg gcataatatt tcggtagact
     3421 taatcaccac gtcagaagtg agcgtggcat taacccttga taccaccggt tcaacctcca
     3481 ctggcgatac gttgctgacg caatctctgc tgatggagct ttccgcactg tgtcgggtgg
     3541 aggtggaaga aggtctggcg ctggtcgcgt tgattggcaa tgacctgtca aaagcctgcg
     3601 gcgttggcaa agaggtattc ggcgtactgg aaccgttcaa cattcgcatg atttgttatg
     3661 gcgcatccag ccataacctg tgcttcctgg tgcccggcga agatgccgag caggtggtgc
     3721 aaaaactgca tagtaatttg tttgagtaaa tactgtatgg cctggaagct atatttcggg
     3781 ccgtattgat tttcttgtca ctatgctcat caataaacga gcctgtactc tgttaaccag
     3841 cgtctttatc ggagaataat tgcctttaat ttttttatct gcatctctaa ttaattatcg
     3901 aaagagataa atagttaaga gaaggcaaaa tgaatattat cagttctgct cgcaaacgaa
     3961 ttcccgtaca ctgaactctc tggctcactg agggcaccat catggcactc ccccgtatta
     4021 cccaaaaaga gatgactgaa cgcgagcagc gtgaacttaa aacactgctg gatcgggcgc
     4081 ggattgcgca tggtcgcgta ttgaccaact ccgaaaccaa cagcattaag aaagattaca
     4141 tcgataaatt aatggttgag cgtgaggctg aagcgaaaaa agcccgccag ttgaagaaaa
     4201 agcaggctta taaaccggat cctgaagcgt catttagctg gtcagcaaat acgtcgacgc
     4261 gcggcaggcg ctaatccaca atcaacgcct gagattttca ctcgtcagtg tgaacacaat
     4321 tttcccctca ccctaaccct tttcccgaag gggcgagggg actgtccggg cacttttggg
     4381 ccgttttcat cagtctgagg cgttaatcag cgccccttct ttttacgccc cggcgaggta
     4441 aaacgcttac cgttggacgc cgggcgaccg cctttttccg ccgttttttc catcttaacg
     4501 actggacgtt tgatgcccgc tgttttcggt ttggccttcg ctttaggttt tacctcggaa
     4561 gaggaatttt caatgagctt aaagaggtcg attaactcat cgtcggttaa atcgcgccat
     4621 tcccccagcg gaatgccgct taagctaacg ttcatgatgc gcgtgcgttc cagctttttc
     4681 acttcatagc cgaaatgctc gcacatgcgc cggatctgac ggttcagccc ctgcaccagg
     4741 gtaatgcgga agacaaacgg cgcttctttt ttaactttgc actttttggt cactgtcccg
     4801 aggattggca cccccgcact catgccgcga ataaactcct cggtaatcgg tttatcgacc
     4861 gtcaccagat actctttctc atgatcattg ccagcacgca ggatcttatt caccagatcg
     4921 ccgtgattgg tgaggaaaat cagcccctgg gagtctttat ccaggcggcc aatcgggaac
     4981 acgcgtttgc tgtggttaac gaaatcgaca atgttatcgc gctcgccatc ttcggtggtg
     5041 cttacaatac caacgggctt gttcagggcg ataagtacca aatcttcggc ttcccgaggt
     5101 tcaatcaact gaccgtttac tttcacaacg tcgccgggtt tcacctgatc gccaatggtg
     5161 gctcgcttgc cattaaggaa cacattgcct tgctcgatat agcgatccgc ttcgcggcgt
     5221 gagcaaattc cgctttcgct gatgtattta tttaaacgga ctgatgagtc gggcagcata
     5281 aattctcctg taaaaaacgg aatataccgt acctttgggt tgataaaaaa tagtcatgag
     5341 cgaactattt gttatttcca ttggcttgaa ttcgttacct gctcaaatca ctttccagaa
     5401 gcaatgtgcg acatcgtgag ccatgtcagt aagtggttaa attcgcagtg gtagcatgcc
     5461 tcccgtgatt tcttactaac cggagaagta atggaactgc ttttattgag taactcgacg
     5521 ctgccgggta aagcctggct ggaacatgca ctgccgctaa ttgctgaaca gttgcagggt
     5581 cgccgctcag cggtgtttat ccctttcgct ggcgtaacgc agacctggga tgattacaca
     5641 gcgaaaacgg ctgcggttct cgctccgctg ggtgtttctg tcaccggtat tcatagcgtt
     5701 gtcgatcccg ttgccgcgat tgaaaatgct gagatcgtga ttgtcggcgg cgggaatact
     5761 ttccagttgc tgaaacagtg ccgcgagcgc gggctgctgg caccaattac tgacgtggtt
     5821 aaacgtggcg ctctgtatat tggctggagc gcaggcgcta accttgcttg cccaactatt
     5881 cgtaccacca acgatatgcc gattgtcgat ccgcaaggtt tcgatgcgct aaatctgttc
     5941 ccgctgcaaa tcaacccgca cttcaccaac gcgctgccgg aaggccataa aggtgaaacc
     6001 cgtgagcagc gtattcgcga actgctggtc gtcgcgccag aactgacgat tattggtcta
     6061 ccggaaggta actggatcac agtgagtaaa ggtcacgcta cgctgggtgg cccgaacacc
     6121 acttatgtgt ttaaggctgg tgaagaagcg gttccgctgg aagctggtca ccgtttttaa
     6181 gtgaattgcc ggatgcatga tccggcatct tgttcatagt gcctgatgcg acgcttgacg
     6241 cgtcttatca ggcctacagg attcacaata ttaatactcg tcccgtcctt catcttcatc
     6301 cggctgttcc agcacactgt aagccaccga acaaaacagc gagttcaggc gctgcatatc
     6361 tcccagtaag cctaaatgta gcgaactggt ttcaatgctc tgcacgtttt gctgatgcag
     6421 gcgatcgacg tgggcgtggg aatagcggcg attaagaatg cgaaaacgat gtttgctgcg
     6481 acgcaaacga cgagcgctgg tgacatcgcc agagaagaac accgacattg ccagctttaa
     6541 attactgagc aattgctcat agagcgcatc cagttccttc aacccatcaa gcgaaaatgc
     6601 ccgccgtgct gccagtgatt tgtcagcaat ttcgctgccc atgcgctcga cgatatcgga
     6661 ggcctgttca aggttgagcg acatttcgat gatctctgcc cagcggcgcg actcttcctc
     6721 cgccagctct tcttttggca tccgcgccag atacagctta atggcggtgt agagaacgtt
     6781 gatatcatct gccagcttac gcagctcttt ctcctgccgt ggctcaccgt gcatcacttt
     6841 attcaaccct tccatcatct gttccatggc gtcgccaatg cgcagggttt cgcgcgcggc
     6901 gttcgccaga gcaagcgtgg gcgtatccag cgcgctgaca tccagatgtt taggccgtag
     6961 ctgggtatcc agttccggtt catcgcgaat aatcgttttg caaaaccgtg ccatcgggtc
     7021 aacaaatggc agcatgacca ggcaacgtac aaggttgtag aagacgtgga aatagatcac
     7081 cagttccgct tttggcaatg acaacttccc cattgtctct gccagcaaat ggacaaacgg
     7141 caggataatc aggctaccca ccagcttaaa cagcagacta cccagcgcga cacggcgggc
     7201 tgcggcattg gcggcactgt tgttgagcat tgccagcaga ccggaaccga ggttagcacc
     7261 aatcaccaga cagagcgcca cggggaagga gataatgcct gcggcggtca gagtcgcggt
     7321 cagcagtaca gcagcaaggc tggagtagct gataatggcg aacatcgcgc caatcagcgc
     7381 atccagcaga atatcgccgg tcagcgaggc aaagatcacc tgaacgccgt ttgcctgggt
     7441 gatcggcgtt acggcctgca caatcaactc cagcgctagc aaaatcagcc caagaccaat
     7501 accgacgcgg cccagttgcc cggcgcgtga ctgtttgcgt ccgaggaaaa aaatcacgcc
     7561 gataaaaata agtaacggtg acagccagga taagtcgaag gtgagaatac gcgccattag
     7621 cgccgtcccg acatctgcac ccagcacaat gaccagagcc ggtgcgaggg ctaccagatc
     7681 ctgagcgaca aacgaggtca ccagcatggt ggtggcatta ctgctctgta ccagtgcggt
     7741 aacgccgatc cccgcgcaaa aggcgagcgg ctttttttcg acgctccggc taaggacagt
     7801 acgcaaacgc gcgccgaaga cgcgcattac gccggttcga acaatatgag tcccccagac
     7861 cagcagggcg acggcagaaa gcaggtgaag cagcgttaac acgagttcag gttctcctta
     7921 tcgttatatg ttcctgaagc aattgaatga ccaaaggacc ggaaacacgc tgactggcat
     7981 ctttactgtg ccttttgaca ttcgtttttc cggctaagat tattccagcc tgtttccagt
     8041 ataagtgttt catattaata aagagacagg gcactcattg agcgccctgt ttgttgtaag
     8101 gaaaagtgac agatttgtga atcagtccgc gtcatacccc agattcggtg ccagccagcg
     8161 ctcaacttcg gtaacgctca tacctttacg gcgggcataa tcttcaacct gatcgcgctg
     8221 aatttgtgct acagcgtagt acttgctgtc cgggtggctg aagtaccaac ccgaaaccga
     8281 tgcaccgggc cacatggcga aagattctgt gagtttcatg ccagtgtgtt tttccacttc
     8341 cagcagctcc cagatggtgg ctttttccgt atgttccggg caggccggat agcccggtgc
     8401 cggacggatg ccctggtagt tttcgcggat cagctcttcg ttgctgaggt tctcgttcgg
     8461 cgcatagccc cagtagactt tacgcacacg ctcatggaga tactccgcaa aggcttcggc
     8521 taaacggtcg gcaagcgctt tcaccatgat tttgttgtaa tcatcgtgct gcgcttcaaa
     8581 ggcatcagcc agtgcgtcct cttccagccc gccagtcacg gcaaatgcgc cgatgtaatc
     8641 tgctttacca gaaagcttcg gcgcaacgaa gtcagcgaga cagtagttag cgaagcctgt
     8701 tttttcggtc tgttgacgca gatggtggct gacgttgatc acatgggtac gcgtttcgtc
     8761 acggtagatt tcaatgtcat cgcccacacg gtttgccggg aacaggccca ccacgccacg
     8821 cggattcagc gttttctcgg cgcttaattt atccagcatg tcgttggcgt ctttaaacag
     8881 ccgctgcgcc tcaacgccca ccacttcatc ttccagaatg cgcggatact tcccggccag
     8941 cgaccaggtc ataaagaacg gtgtccagtc gatgtaatta cgcagcgttt cgatgctggc
     9001 ttcgacttcc tgcacgccga gacggtgcgc caccggcggc gtgtaagcct gccagtcaaa
     9061 agcgaaatcg ttatcgcgcg ccgcttccag cgtgaccggt ggtgtgcgcg gtttcttgcg
     9121 cccgtgctga atacgtacgg tttcgtactc cttgcgggta cgagcgacaa aatcatcacg
     9181 ctgggtatcg gaaagcagcg ccgccaccac accaacggta cgcgaggcat tctgcacata
     9241 caccgtcggg ccgctgtagt tctgctcgat tttcaccgcc gtgtgcgctt ttgaggtcgt
     9301 cgcgccgcca atcagtaacg gaatagtgaa gccctgacgc tccatctctt tcgccacgtt
     9361 aaccatctcg tccagcgacg gcgtgataag ccccgaaagg ccaatcagat cagcattcac
     9421 ttctttagcg gtacggagaa ttttttccgc aggcaccata acgccgagat cgacaatttc
     9481 gtagttgtta cattgcagca ccacaccaac gatattttta ccgatgtcgt ggacgtcgcc
     9541 cttcacggtg gcgatcacca tcttgccgtt ggttttgccc tgctctttgc tggcttcaat
     9601 aaacggttcg aggtaggcca ccgcctgttt catgacgcgc gccgatttga ccacctgtgg
     9661 caggaacatt ttcccttcgc caaacaggtc gccgaccaca ttcatgccgt ccatcaacgg
     9721 gccttcaatc acttcaatcg ggcgcgtagc ctgctggcgg gcttcttcgg tatcctgctc
     9781 gataaactcg gtaatgcctt tgaccagcga gtattccaga cgtttattca cttcccacga
     9841 gcgccactcc gcctgctggg cgttggcggt gtcgtcggtt ttgctgccgc gatatttctc
     9901 ggcaagctcc agtaaacgct cggtgccatc gtcacgacga ttaagaatca catcttccac
     9961 cgcgtcgcgc agttcagcgg gtaggtcgtc gtaaatcgcc agttgcccgg cgttgacgat
    10021 ccccatatcc atgccattgc gaatagcgta gtagaggaac actgcgtgaa tggcttcgcg
    10081 caccggatcg ttgccacgga acgagaaaga aacgttagat acgccgccgg aaatcagcgc
    10141 gtgcggcagt tcgcgtttga tgtcttcaca cgcgccgata aagtcctgcg cgtagttgtt
    10201 gtgctcttca atgccagttg cgaccgcgaa gatgtttggg tcgaagatga tatcttctgg
    10261 cgggaagcca acctcttcgg tgaggatttt gtacgcccga cggcaaatct cgattttccg
    10321 tgcgcgagta tcggcctgtc cctgttcgtc aaaggccatt accaccactg ccgcaccgta
    10381 gcgacgcaac aatttcgcgt gatggataaa ggcatcgacg ccctctttca tcgagataga
    10441 gttaacaatg cctttgccct ggatacactt cagacctttt tcaatgacgt cccattttga
    10501 ggagtcgatc ataatcggca cgcgagcgat atccggttca ccggcaatca gattgagaaa
    10561 acgcaccatc gccgcttcgg catcgagcat cccttcatcc atgttgatat cgataatctg
    10621 cgcgccgttt tccacctgtt gacgcgcgac atccagcgcc tcgctgtatt tctcttcttt
    10681 gatcaggcgc ttgaacttag cggaaccggt gacgttggtg cgttcaccca cgttcacaaa
    10741 caggctatct tcgccaatgt tcagcggctc caggccggac aaacggcagg ctacgggaat
    10801 ttccggcagt ttgcgcggcg ctaatccttc tactgcacga ctcatcgctg caatatgttg
    10861 tggcgtggtg ccacagcagc cgccgacgat attgagaaaa cccgcttgcg cccattcacg
    10921 tatctgtttt gccatcgtgt cggcgtcgag atcgtactca ccaaaggcgt tgggtagccc
    10981 ggcgttcggg tgcgcggtga cgtagcattc cgcaatccgt gacagctcct gcacgtactg
    11041 gcgcagttca tcgggcccca gcgcacagtt caggccaaag gtcagagctt cggcgtggcg
    11101 caatgagttg taaaatgctt cggtggtctg cccggagagc gtgcgcccgg aggcgtcggt
    11161 gatggtgccg gagatcataa tcggcagctc aacgcccagc gcttcaaact ccgttttcac
    11221 cgcaaatacc gccgctttgg cgttaagggt gtcgaaaacg gtttcaatca ggatcagatc
    11281 cgcgccacct tccaccagcg ctttggtgga ctctcgataa gccgccacca gcccgtcaaa
    11341 agtgatatta cgaaatgccg gatcgttgac gtccggagaa atagacgccg tgcggttggt
    11401 cgggccgaga acaccggcaa cgtagcgcgg tttctctggc gtgcgcgcgg tccactcgtc
    11461 agcacaagct cgcgccagtt tcgccgccgc aaagttgatt tccgccgaca gggattccat
    11521 ctggtaatcc gccatcgcaa tggtcgtgga gttgaaggtg ttggtttcga tgatatccgc
    11581 gcccgcttca aagtaggcgt tgtggatagc ggcgatcact tccggtttac tgagtaccag
    11641 caggtcgttg ttgcctttga ggtcgcatgg ccagtcggca aagcgttcac cacgaaaatc
    11701 ggcttcgttc agtcgataac tctggatcat ggtgcccata ccgccgtcca gcaccagaat
    11761 acgttcattt aactgcgcac gcagttgttc cactttgctg ctcacacttg ctcccgacac
    11821 gctcaaccca gatttaataa aaattcaaca aaccatactg gcataaacgc atctgtggta
    11881 aaagcgacca ccacgcaaca tgagatttgt tcaacattaa ctcatcggat cagttcagta
    11941 actattgcat tagctaacaa taaaaatgaa aatgatttcc acgatacaga aaaaggagac
    12001 tgtcatggtc gcacccattc ccgcgaaacg cggcagaaaa cccgccgttg ccaccgcacc
    12061 agcgactgga caggttcagt ctttaacgcg tggcctgaaa ttactggagt ggattgccga
    12121 atccaatggc agtgtggcac tcacggaact ggcgcaacaa gccgggttac ccaattccac
    12181 gacccaccgc ctgctaacca cgatgcaaca gcagggtttc gtgcgtcagg ttggcgaact
    12241 gggacattgg gcaatcggcg cacatgcctt tatggtcggc agcagctttc tccagagccg
    12301 taatttgtta gcgattgttc accctatcct gcgcaatcta atggaagagt ctggcgaaac
    12361 ggtcaatatg gcggtgcttg atcaaagcga tcacgaagcg attattatcg accaggtaca
    12421 gtgtacgcat ctgatgcgaa tgtccgcgcc tatcggcggt aaattgccga tgcacgcttc
    12481 cggtgcgggt aaagcctttt tagcccaact gagcgaagaa caggtgacga agctgctgca
    12541 ccgcaaaggg ttacatgcct atacccacgc aacgctggtg tctcctgtgc atttaaaaga
    12601 agatctcgcc caaacgcgca aacggggtta ttcatttgac gatgaggaac atgcactggg
    12661 gctacgttgc cttgcagcgt gtattttcga tgagcaccgt gaaccgtttg ccgcaatttc
    12721 tatttccgga ccgatttcac gtattaccga tgaccgcgtg accgagtttg gcgcgatggt
    12781 gattaaagcg gcgaaggaag tgacgctggc gtacggtgga atgcgctgac tttttctggc
    12841 gggcagaggc aatattctgc ccatcatacc tgagtggcaa tagaataagg gtgtctgtta
    12901 atcgcattga cgccaaaata acttaatgtc atacacttca cacactttta ttaactcagc
    12961 attattttta aacatcaaac cacttaatta ttaacaaaat cgcaagatct cattccaccg
    13021 aaacttttac ggctgcatta tgagattgag cgatttatga tattt
//
LOCUS       DAPHKZ010000127        13012 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.127, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000127 DAPHKZ010000000
VERSION     DAPHKZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13012
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.127"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            327..908
                     /gene="mdaB"
                     /locus_tag="RH288_003735"
     CDS             327..908
                     /gene="mdaB"
                     /locus_tag="RH288_003735"
                     /EC_number="1.6.5.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone oxidoreductase MdaB"
                     /protein_id="HDV4032749.1"
                     /translation="MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRA
                     DSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRK
                     DPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
                     EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG"
     gene            939..1253
                     /locus_tag="RH288_003736"
     CDS             939..1253
                     /locus_tag="RH288_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDV4032750.1"
                     /translation="MLTVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMV
                     DCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPHMKAYSEAVKGDVLEMNIRILQP
                     GI"
     gene            complement(1301..3193)
                     /gene="parE"
                     /locus_tag="RH288_003737"
     CDS             complement(1301..3193)
                     /gene="parE"
                     /locus_tag="RH288_003737"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDV4032751.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDG
                     LNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLASQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVK
                     HFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGD
                     MAEIEV"
     gene            complement(3222..3803)
                     /gene="yqiA"
                     /locus_tag="RH288_003738"
     CDS             complement(3222..3803)
                     /gene="yqiA"
                     /locus_tag="RH288_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HDV4032752.1"
                     /translation="MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYP
                     SDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL"
     gene            complement(3803..4630)
                     /gene="cpdA"
                     /locus_tag="RH288_003739"
     CDS             complement(3803..4630)
                     /gene="cpdA"
                     /locus_tag="RH288_003739"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HDV4032753.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQA
                     VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLL
                     ATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY"
     gene            complement(4655..5077)
                     /locus_tag="RH288_003740"
     CDS             complement(4655..5077)
                     /locus_tag="RH288_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HDV4032754.1"
                     /translation="MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQ
                     YRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY"
     gene            complement(5078..5707)
                     /gene="nudF"
                     /locus_tag="RH288_003741"
     CDS             complement(5078..5707)
                     /gene="nudF"
                     /locus_tag="RH288_003741"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HDV4032755.1"
                     /translation="MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQ
                     MSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEG
                     ESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA"
     gene            5912..7393
                     /gene="tolC"
                     /locus_tag="RH288_003742"
     CDS             5912..7393
                     /gene="tolC"
                     /locus_tag="RH288_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HDV4032756.1"
                     /translation="MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAA
                     DRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK
                     WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
                     QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAAL
                     NVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTAST
                     GISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGA
                     SEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIV
                     DVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
                     NVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN"
     gene            7541..8212
                     /locus_tag="RH288_003743"
     CDS             7541..8212
                     /locus_tag="RH288_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417509.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HDV4032757.1"
                     /translation="MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSS
                     RSMGG"
     gene            8218..9378
                     /locus_tag="RH288_003744"
     CDS             8218..9378
                     /locus_tag="RH288_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HDV4032758.1"
                     /translation="MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLAQ
                     VEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPKHTWSFVRQSWLTHQPSLYSRLD
                     LAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
                     RFVELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVISNLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPNHPNLLPAYFAEDDHPQMEKYVVKPIFSREGANVSIIENGKTIEAAEGPYGEEGMI
                     VQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE"
     gene            complement(9416..10204)
                     /gene="ygiD"
                     /locus_tag="RH288_003745"
     CDS             complement(9416..10204)
                     /gene="ygiD"
                     /locus_tag="RH288_003745"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HDV4032759.1"
                     /translation="MSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMTLPRPQAIVV
                     VSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPALAQRLVELLAPIPVT
                     LDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIML
                     VASGNVVHNLRTVKWHGDSSPYPWATSFNEYVKANLTWQGPVEQHPLVNYLDHEGGTL
                     SNPTPEHYLPLLYVLGAWDGQEPITIPVEGIEMGSLSMLSVQIG"
     gene            10347..11120
                     /gene="zupT"
                     /locus_tag="RH288_003746"
     CDS             10347..11120
                     /gene="zupT"
                     /locus_tag="RH288_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDV4032760.1"
                     /translation="MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIM
                     LLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLP
                     KSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG"
     gene            complement(11178..11348)
                     /locus_tag="RH288_003747"
     CDS             complement(11178..11348)
                     /locus_tag="RH288_003747"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032761.1"
                     /translation="MFIAWYWIVLIALVVVGYFLHLKRYCRAFRQDRDALLEARNKYL
                     NSTREETAEKVE"
     gene            complement(11610..12263)
                     /gene="ribB"
                     /locus_tag="RH288_003748"
     CDS             complement(11610..12263)
                     /gene="ribB"
                     /locus_tag="RH288_003748"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HDV4032762.1"
                     /translation="MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS"
     regulatory      complement(12367..12515)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            12637..12927
                     /gene="ubiK"
                     /locus_tag="RH288_003749"
     CDS             12637..12927
                     /gene="ubiK"
                     /locus_tag="RH288_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HDV4032763.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRISELENRSTEIKKQPDPETLPPTL"
BASE COUNT         3297 a         3471 c         3162 g         3082 t
ORIGIN      
        1 tttaacatat atcagtacgc tcataaaaat ccatttataa ttatcaacat gacacgttga
       61 tactttcatc ttttacttat tcaaagccat attttcaatc cccaaaaaaa ccgaaccaaa
      121 cgtgtaaatt attccggtgc gagtaagaat tatgaggaat ggctatcagt attgtcattt
      181 tcagaaaata tttatcctgc atcggtgagt cagagtaaga tcagactttt gctaaattcg
      241 caaaagactt tgcacatttt gctaatttca ccgtaccgct ctgtgacgta ctatagtcgg
      301 caaacgtctc accttgaggt taaaaaatga gcaacatcct gattatcaac ggcgcgaaaa
      361 aattcgccca ctccaatggt caactgaacg acaccctgac cgaagtcgcg gatggcacac
      421 tgcgcgacct tgggcatgat gtccgcatcg ttcgcgccga cagcgactac gatgtcaaag
      481 cggaagtaca aaactttctc tgggctgatg tggtgatctg gcagatgcca ggctggtgga
      541 tgggcgcgcc gtggacagtg aaaaaataca ttgatgatgt attcaccgaa ggtcacggga
      601 cgctgtatgc cagcgatggt cgtacccgca aagatccgtc gaaaaaatac ggttccggcg
      661 gcctggtaca gggcaaaaaa tatatgcttt ctctgacctg gaacgcacca atggaagcct
      721 tcaccgaaaa agatcagttc ttccacggcg ttggcgttga cggtgtgtat ctgccgttcc
      781 ataaagcaaa ccaattcctc ggtatggaac cgctgccgac atttatcgct aatgacgtga
      841 taaaaatgcc tgatgttccc cgctatactg aagaatatcg caagcatctt gtggaaattt
      901 ttggttaact agagctcagg ctttagaagg agttaaccat gcttaccgta atcgcagaaa
      961 tccgtactcg tcctggtcaa catcaccgtc aggcggtatt ggatcagttt gctaaaatcg
     1021 ttccaaccgt actgaaagaa gaaggttgcc acggctatgc gccaatggtg gattgcgcag
     1081 ctggcgtgag tttccagtct atggcaccgg attctatcgt gatgattgag cagtgggaaa
     1141 gcatcgcgca tcttgaagcg catctgcaaa ccccgcacat gaaggcgtat agcgaagccg
     1201 taaaaggtga cgtgctggag atgaatatcc gtattctgca gccagggatt taatcctgcc
     1261 ttgtttgccc ggccatcctg accgggcaat gttctttcct ttaaacctca atctccgcca
     1321 tgtcgccttt ctcttgcaac cagttgcggc gatcttccga gcgtttcttc gccagcagca
     1381 tatccatcat cgcgtcagta cgctgatcgt cttcatcatc gatagtcaac tgcaccagac
     1441 ggcgagtgtt cggatcaagc gtggtttcgc gcaattgcat cgggttcatt tcccccagac
     1501 ctttaaaacg ctggacgttc ggcttgcctt tcttgcgttt taattgctca agtacgccct
     1561 ctttctcttc ttccgtcagc gcgtaataaa cctctttccc gagatcaata cggtagagcg
     1621 gtggcagtgc gacgtaaacg tgaccgtgtt tcaccaacgc gcggaaatgt tttacgaaca
     1681 aagcgcagag cagcgtggca atgtgcagac catcagagtc cgcatccgcg aggatacaga
     1741 ttttgccata acgaagctgg ctcagatcgt cgctgtcagg atcgataccg atcgctaccg
     1801 aaatatcgtg cacttcctgc gaagccagca cttcgtcgga agagacttcc caggtgttaa
     1861 ggatcttacc tttcagtggc atgatcgcct gatattcgcg atcgcgcgcc tgcttggcag
     1921 atccgcctgc ggagtcacct tccacaagga acagctcggt acggttaagg tcctgcgcgg
     1981 tacaatcagc cagtttgcca ggcaacgccg ggccgctggt cagcttttta cgcaccactt
     2041 ttttggccgc acgcatacgg cgctgggcgc tggaaatcgc catctccgcc agcagttcag
     2101 ccgcctgaac gttctggttc agccacagga taaaggcatc tttcaccacg ccagaaacga
     2161 atgccgcgca ttgacgcgaa gagagacgct ctttcgtctg cccggcaaac tgcggatcct
     2221 gcatttttac tgacagcaca taggcgcagc gatcccagat atcttccgcc gacagcttta
     2281 caccgcgcgg cagaatattg cggtattcac agaactcacg catcgcgtcc aacaggccct
     2341 gacgcagacc attaacatgg gtaccgccct gcatcgttgg gataaggttg acgtagcttt
     2401 cggtcagcag ttcaccgcct tccggcagcc acagtagcgc ccagtccaca gcttcagtat
     2461 caccagcgaa attaccgata aacggttttt ccggcagcgt cggcagacca tttaccgctt
     2521 ccgccaggta atcattcaga ccgtcctgat agcaccagcg ttgttcggta ttgttgatct
     2581 catctttaaa agtgatctca acgccagggc acaataccgc tttggctttc agcacatgcg
     2641 tcaggcgtga aacagaaaat cgcgggctgt caaagaaggt ttcatccggc cagaagtgca
     2701 cactggtacc agtattgcgt ttaccgcaag tgccgacaac ctgtaaatcc tgcacctttt
     2761 cgccattttc aaaggcgatg ttataaacct gaccatcgcg gcgcacgtta acttctacgc
     2821 gcttcgacag ggcgttaacc accgaaatcc ccacgccatg caggccgcca gagaactggt
     2881 aatttttgtt agagaattta ccgcctgcat gcagacggca aagaatcagt tcaaccgccg
     2941 gtacaccctc ttccgggtga atatccaccg gcatcccgcg cccatcgtca ataacttcta
     3001 acgactggtc agcatgtaaa ataacgtcca cgcgttttgc gtgacccgcc agtgcttcat
     3061 ccacactgtt atcaatgact tcttgcccca aatggttagg gcgagtggta tcggtataca
     3121 tccccggacg gcggcgaacc ggctcaagcc cggtgagtac ctcaatggca tcagcgttat
     3181 aagtttgcgt catggtttaa gttagtaatt cgagttgatc gtcagagatg gtgcagacca
     3241 agaaaatcga cgatcgggtt gaaataatct tcgaagcccg tgaatgcgtg gttgccgcct
     3301 tctatgacag tctggcggca ggaagcgtag tacgccaccg cctggcggta atccagcact
     3361 tcatctcccg tctgttgcag cagccagatc aaatccggcg cttccagcgg gtcaatctgc
     3421 atgactttaa gatcgtaaat atggcgtgac tctagcacat attgctgccc ggtgtagggg
     3481 ttctcgttct gaccgagata gtccgtcagc agttcaaacg ggcgcaccgc cgggtttacc
     3541 accactgcgg gcagcataaa acattgtgac aaccaggtgg cgtaatatcc ccccagtgac
     3601 gaaccgacaa tacccagcga atcaccgcca tgttccagga caatggattc cagcagctct
     3661 gccgcgtcgg aaggatacgg cggcaactgc ggaatgatca tctcaacgtc agggtgatgt
     3721 tccgccagcc agttttttaa caagctcgct tttgcagagc gcggcgagct gttgaaaccg
     3781 tgtaaataaa gaagcgtaga catcagtagc cttctgaagc ggtatcaggt tggaaacgtg
     3841 tgtccgccag gcgatgcacc tcggtggtca gcgtgccatc agcatgtaac tcgagagtac
     3901 gccagccggg cgcgatggta tccagcgtaa agttggaaca gtgcggctta aactgcacac
     3961 aggtcgacgg cgttgccagc aggcggcgac cattccagtc gagatccagc tcctgatgaa
     4021 tatgaccgca cagcaagtat ttgacgtgcg gaaacttcgc cagcacggta tccagttcgc
     4081 ccgcgttacg cagactgtgt tgatcgagcc aactacaacc cgcaggtagc ggatgatgat
     4141 gcagcagcag caacgtatgg cgttctggcg catcggccag tttacgttcc agccactcaa
     4201 gctgaaactc gctcagctca ccgtgcggca cgccaaacac ctggctatcc agcaacagga
     4261 tttgccattg ctcaccaata aacacgcgct tcgccgggga gatacccgca tcctgtaacg
     4321 cgctgtacat cgcgggctgg aaatcgtggt tgcccggcag ccagacgcag ggcgcacgaa
     4381 aacttgcgat gccttcagcg aaatgctgat aggccgcaga ggattgatcc tgcgctaaat
     4441 cacctgtcgc gacaatcagg tcgaattcgt gctggtgtgg ccgaatcgcc tccagcaccg
     4501 cctggtaact ctcccaggtg tttaccccta acagggcttc gtgcttttgt gcaaacaggt
     4561 gagtgtcggt aatttgtaaa atcctgactc tggcctcacc agccagagga agggttaaca
     4621 ggctttccaa atggtgtcct taggtttcac gacgctaata aaccggaatc gccatcgctc
     4681 catgtgctaa acagtatcgc aaccagtccg ctaaaaactg attaatttga tgcttttcgt
     4741 cgcgttgatg caacttttta ttaggataat cataccgcgc tttgaagcga aaaatctgct
     4801 ggcttgaaca cacttcagcc accatcgcgt catgatacag acgcaccgtc attgacggaa
     4861 ggctccagta actgatcgcg ggcgcagtct gttctattgt caccagggta gtgtatcggg
     4921 tcgattccac aatcgtcagc cgatattgtg cgtttgccac ctgatagctt acagtttcgc
     4981 cgggtgcgtc attgcgcggt aacaaacggc gcaattgtga aaagttcatc tcgcacaggc
     5041 gcatcatttc aggaaagtca ggtgtgtaac gcttcattta tgcccactca ttttttaacg
     5101 cttgatgatg cagctgcagc cattgcaaag cgatgaccga cgctgcgttg tcgattttcc
     5161 cctcttctac ccactggtat gcctgttccc ggcttaccac atgaacgcga atatcttcgt
     5221 tttcatcagc cagaccgtga ataccgcttg cggtcgtggc gtccacttcg cccaccataa
     5281 ttgacgaacg ctcactggtg ccccccgggc ttgccaggaa acttaacacc ggtttggtcc
     5341 gtttgactat cagtcccgcc tcttcaatcg cttcgcgacg ggcaacatct tccacacttt
     5401 caccctcttc aatcatcccg gcaaccatct ccagtagcca aggggtttcg ctggtgtcgt
     5461 acgcggcaat ccgaatctgc tcaatcagca caacttcatc acgcactggg tcaaagggta
     5521 gcaagactgc ggcgtgaccg cgctcaaaaa tttcccgccg cacctcatga ctcatttgcc
     5581 cgttgaatag acgatgacga aatctataaa gatctaatga aaaaaagccg cgataaagtg
     5641 tttctcgtgc aataatttct acatcgtttt tgccaaatgt aacgggcagg ttgtctggct
     5701 taagcattgt taatgtcctg gcactaatag tgaattaaat gtgaatttca gcgacgtttg
     5761 actgccgttt gagcagtcat gtgttaaatt gaggcacatt aacgccctat ggcacgtaac
     5821 gccaaccttt tgcggtagcg gcttctgcta gaatccgcaa taattttaca gtttgatcgc
     5881 gctaaatact gcttcaccac aaggaatgca aatgaagaaa ttgctcccca ttcttatcgg
     5941 cctgagcctt tctgggttca gttcgttgag ccaggccgag aacctgatgc aagtttatca
     6001 gcaagcacgc cttagtaacc cggaattgcg taagtctgcc gccgatcgtg atgctgcctt
     6061 tgaaaaaatt aatgaagcgc gcagtccatt actgccacag ctaggtttag gtgcagatta
     6121 cacctatagc aacggctacc gcgacgcgaa cggcatcaac tctaacgcga ccagtgcgtc
     6181 cttgcagtta actcaatcca tttttgatat gtcgaaatgg cgtgcgttaa cgctgcagga
     6241 aaaagcagca gggattcagg acgtcacgta tcagaccgat cagcaaacct tgatcctcaa
     6301 caccgcgacc gcttatttca acgtgttgaa tgctattgac gttctttcct atacacaggc
     6361 acaaaaagaa gcgatctacc gtcaattaga tcaaaccacc caacgtttta acgtgggcct
     6421 ggtagcgatc accgacgtgc agaacgcccg cgcacagtac gataccgtgc tggcgaacga
     6481 agtgaccgca cgtaataacc ttgataacgc ggtagagcag ctgcgccaga tcaccggtaa
     6541 ctactatccg gaactggctg cgctgaatgt cgaaaacttt aaaaccgaca aaccacagcc
     6601 ggttaacgcg ctgctgaaag aagccgaaaa acgcaacctg tcgctgttac aggcacgctt
     6661 gagccaggac ctggcgcgcg agcaaattcg ccaggcgcag gatggtcact taccgactct
     6721 ggatttaacg gcttctaccg ggatttctga cacctcttat agcggttcga aaacccgtgg
     6781 tgccgctggt acccagtatg acgatagcaa tatgggccag aacaaagttg gcctgagctt
     6841 ctcgctgccg atttatcagg gcggaatggt taactcgcag gtgaaacagg cacagtacaa
     6901 ctttgtcggt gccagcgagc aactggaaag tgcccatcgt agcgtcgtgc agaccgtgcg
     6961 ttcctccttc aacaacatta atgcatctat cagtagcatt aacgcctaca aacaagccgt
     7021 agtttccgct caaagctcat tagacgcgat ggaagcgggc tactcggtcg gtacgcgtac
     7081 cattgttgat gtgttggatg cgaccaccac gttgtacaac gccaagcaag agctggcgaa
     7141 tgcgcgttat aactacctga ttaatcagct gaatattaag tcagctctgg gtacgttgaa
     7201 cgagcaggat ctgctggcac tgaacaatgc gctgagcaaa ccggtttcca ctaatccgga
     7261 aaacgttgca ccgcaaacgc cggaacagaa tgctattgct gatggttatg cgcctgatag
     7321 cccggcacca gtcgttcagc aaacatccgc acgcactacc accagtaacg gtcataaccc
     7381 tttccgtaac tgatgacgac gacggggctt cggccccgtc tgaacgtaag gcaacgtaaa
     7441 gatacgggtt atctgccgca ttcttccccc ttctcgcttc aatttcgacc agccatcctc
     7501 tattctgatg ggtatttacc actggtcccg gaagacaaaa atgaaacgga caaaatccat
     7561 acgccacgca tcgttccgca aaaactggag cgcacgccat ctgacaccag tcgctctcgc
     7621 ggttgccact gtttttatgc tggctggctg tgaaaagagt gatgaaacag tgtctctcta
     7681 tcaaaatgct gacgactgtt cagctgcaaa cccaggcaaa agcgccgaat gtaccaccgc
     7741 gtacaacaat gcgctgaaag aagccgaacg tactgcgccg aaatacgcca cccgtgaaga
     7801 ctgtgttgct gaatttggtg aaggtcagtg ccagcaggca ccagcccagg ctggcatggc
     7861 accagaaaac caggcgcagg cccagcaatc cagcgggagt ttctggatgc cgctgatggc
     7921 cggttacatg atggggcgtc tgatgggcgg cggcgcggga tttgcacagc agccgctgtt
     7981 ctcctcgaaa aacccagcca gtccggctta cggtaaatat accgacgcga cgggtaaaaa
     8041 ctatggcgca gcccagccag gccgcaccat gaccgtaccg aagacggcaa tggcaccaaa
     8101 accggcgacc accactaccg ttacccgtgg cggttttggt gaatctgttg ccaaacaaag
     8161 cactatgcag cgtagtgcaa ccggtacctc ttctcgttca atgggtggct gataccgatg
     8221 gaaagagtca gtattaccga gcgcccggac tggcgtgaga aagcccacga atacggtttc
     8281 aattttcaca ccatgtacgg cgagccgtac tggtgtgaag atgcttacta caagttgacc
     8341 ctcgcccagg ttgaaaagct ggaagaagtc accgccgaac tgcaccagat gtgcctgaaa
     8401 gtggtggaaa aagtgatcgc cagcgatgag ctgatgacca aattccgcat tccaaaacac
     8461 acctggagtt ttgtgcgcca gtcatggctg acgcaccagc catcgcttta ttcgcgtctt
     8521 gatctggcgt gggatggcac tggtgaacct aaacttctgg aaaataacgc cgatacgcca
     8581 acgtcactat acgaggcggc gttctttcag tggatctggc tggaagatca gcttaacgcc
     8641 ggtaacttgc cggagggcag cgaccagttt aacagtctgc aagaaaaact gatcgatcgc
     8701 ttcgttgagc tgcgtgaaca gtatggcttc cagttgctgc atctcacctg ctgtcgcgac
     8761 acggtggaag atcgcggaac cattcagtat ttgcaggact gcgcaacgga agctgaaatt
     8821 gctactgagt tcctctacat cgatgatatc gggttaggtg aaaaaggtca gttcacggat
     8881 ttacaggatc aggtaatttc caacctgttc aaactgtatc cgtgggaatt tatgttgcgt
     8941 gagatgttct caaccaagct ggaggatgca ggcgtacgct ggctggaacc ggcgtggaag
     9001 agcattatct ccaacaaggc acttctaccg ctactgtggg agatgttccc gaatcacccg
     9061 aacctgctgc ccgcttattt tgcggaagat gatcatccgc aaatggaaaa atatgtggtt
     9121 aaaccgatct tctcccgtga aggcgcaaac gtgtcgatca ttgagaacgg caaaaccatt
     9181 gaagcagcgg aaggtccgta tggcgaagaa gggatgattg ttcagcaatt ccacccgtta
     9241 ccgaaattcg gcgacagcta tatgctgatt ggtagctggc tggtgaacga tcaacccgcc
     9301 ggaattggca ttcgtgaaga ccgtgcattg atcacccagg atatgtctcg gttttatcca
     9361 catatttttg ttgaataagc cacgataccg gatggcactc gccatccggt aattgttagc
     9421 ctatctgcac cgacagcata ctcaggctgc ccatttctat accctcaacc ggaatggtaa
     9481 ttggctcctg cccatcccac gcacctaaca catacaacaa cggcaaataa tgctctggcg
     9541 ttgggttcga taacgtgcca ccttcatggt cgaggtaatt caccagagga tgttgttcca
     9601 ctggcccttg ccacgtcaga ttcgctttca catactcatt aaacgacgtc gcccacggat
     9661 acggtgaact atcaccgtgc cacttcactg tgcgcaggtt atgcaccacg ttaccgctgg
     9721 cgaccaacat tattccttca tctcgcagcg ctgccagttt gcgccccatt tcgaaatgcc
     9781 aggcggcagg tttgctactg tcgatactca actgcaccat cgggatatca gcgtcaggat
     9841 acatcttaat cagcacgccc cacgagccgt ggtcaaagcc ccaggcttct ttatccagcg
     9901 tcaccgggat cggcgctaac agctcaacca gacgctgtgc cagcgcaggc gaacccggag
     9961 caggataatg cgtatcgtac agcgcctgcg ggaagccacc aaagtcatga atcgtgggcg
    10021 gcgtctccat cgcggtcact cctgttccac gggtaaacca gtgagccgaa accaccacaa
    10081 tcgcttgcgg gcgtggcaat gtcatcccca acttctgcca gctgcgggta tacaaattat
    10141 cttccagcac gttcatcgga ctaccgtgac ctaaaaacaa tgctggcata cgtgttgaag
    10201 acatgatgat atccttaact aaaggtgtca ttttgatatc ctcacaatac gcttgttcgg
    10261 cggagtaaga acccggataa caatgatgat gatcatcagt tattttgacg atctgcctga
    10321 aggtgaagat ttataaggag ttgtcgatgt cagtacctct cattctgacc atactggcgg
    10381 gggcagccac gtttattggc gcgtttctcg gcgttctcgg gcaaaaaccc tcgaaccgct
    10441 tactggcgtt ttcgctaggt tttgcggcgg ggatcatgtt gctcatctca ttaatggaaa
    10501 tgcttcctgc cgcactagca gctgaaggaa tgtcgcctgt gttgggttat ggaatgttta
    10561 tcttcggtct gcttggctat tttggcctgg accgcatgtt gccacatgct catccgcagg
    10621 atttaatgca aaaatcggtg cagccgttgc caaaatcgat caagcgcaca gccattctgc
    10681 tcactctcgg catcagtctg cataacttcc cggaagggat tgccaccttt gtcacggcga
    10741 gcagcaacct ggagctggga tttggcatcg cactggccgt cgcgttgcac aatatccctg
    10801 aaggtctggc agtggcaggc ccggtttatg cggcaacggg gtctaaacgc accgcgattc
    10861 tgtgggcggg gatttctgga ctagcagaaa ttcttggtgg tgtgctggcg tggttaatcc
    10921 tcggtagcat gatttccccg gtggtcatgg cggcaatcat ggcggcggtt gcaggaatta
    10981 tggtggcgct ctcggttgat gaattaatgc cgctcgccaa agagattgac cctaataata
    11041 accccagcta tggcgtacta tgtggaatgt cagtgatggg attcagttta gtgctgctac
    11101 aaacggcggg aattggttaa aaacaacatc agaagttgtc cagcgcatgg acaacttctg
    11161 ccagcttcac gaaagcctta ttctaccttt tcggctgtct cttctctcgt actgtttaag
    11221 tatttgttcc gcgcttcaag cagtgcgtct ctgtcctggc gaaacgcccg acaataacgt
    11281 ttcaaatgca ggaaataacc caccacaacc agagcaatca atacaatcca gtaccaggcg
    11341 ataaacatcc ttttaccctt aatatttaac aatactaaac atttagcgta taaatttcac
    11401 atatcctttt tcggatatat tcatatggtc gcataataac ggaacaatta tatgattttg
    11461 atcataatga aaaagaatgc ctgatattaa tgaaattttc tcatagaaag agaagcggaa
    11521 ttaacatctt gcatagcagg gaaaaataaa aaccgaagcc tgctacaact tcggtttctt
    11581 gattaaggca gtaaattaag cagcggtttt cagctggctt tacgctcatg tgcctgacgg
    11641 tatgccacca ggtcttcaat agtcacgagc gccatattgt gtttattggc aaactcaata
    11701 cactctggtg cacgcgccat cgtgccatcg tcattagtca gctcacacag tacaccagcc
    11761 ggtttaaagc ctgccagcgt catcagatca atagttgctt cagtatgacc gccacgcgtc
    11821 agtacaccac ctgcctgagc gcgaagtggg aaaacgtggc caggacgatt cagatctgac
    11881 ggttttgcgc catcggcaat cgctgcgcga acggtcgtaa tacggtcagc ggcagaaaca
    11941 ccggtagtca caccttcagc tgcttcaatg gtcacggtaa aaccggtgcc ataggcgctg
    12001 gtgttatttt ctaccatcat tggcagatcg agttgtttac ggcgatcttc agtaatgcac
    12061 aggcaaacaa taccgctacc gtggcgaatg gtcagcgcca tctgctcaac agtcatggtt
    12121 tctgccggga agatcatatc accttcgttt tcacggtctt catcatcaag caccattaca
    12181 ccgcgtcctt cacgcagcgc agccagtgca ttttcaacac gttcgaaagg cgtaccaaaa
    12241 gaggaaagta gcgtctgatt catggtaaaa aaacctcact aaaattatgg ttaccagaat
    12301 cagggcagtc ttaggagtgg cggcatatag ccaaaataac gtgagcgggt ccatgcccga
    12361 cagaatcgtt actctctccc atccggactc taaccgtcgg ccccggaatt acaccggatc
    12421 tgctgtcctt tgagttcgca cccaaagcgc tcgcgggctt tcaactgagt tgatttaccg
    12481 ccggtgggga atttcgcccc gccctgagaa taagcggatt cactataacg ctaatgatta
    12541 gcggcagcaa cgcatagctt cacataattc tggtttatga cttaccctta tcgcactaca
    12601 atggcactca acacctatca gtacagggaa actacaatga ttgacccgaa aaaaattgag
    12661 caaatcgctc gccaggttca cgaatcaatg cctaaaggaa tcagggagtt cggggaagat
    12721 gtggagaaaa aaatccgcca aaccctacaa gcgcagctga cgcgcctcga ccttgtaagc
    12781 cgtgaagagt tcgacgtcca aacgcaagtc ctgttacgga ctcgtgaaaa actggcgctg
    12841 cttgaacaaa gaatcagcga actggaaaat cgcagtactg agatcaaaaa gcagccagat
    12901 ccagagactc tccccccaac gctgtaaaca ttcgtcttta atgcactgta aattatgaat
    12961 taatcctcta atttatagtg ctttctatta ccttatcgcg taatcccatt ca
//
LOCUS       DAPHKZ010000128        12837 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.128, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000128 DAPHKZ010000000
VERSION     DAPHKZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12837
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.128"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(74..331)
                     /locus_tag="RH288_003750"
     CDS             complement(74..331)
                     /locus_tag="RH288_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032764.1"
                     /translation="MQKPLPVRWLIIQGLTENEHCGIQAYACNTESQEDLYAEVPLVG
                     RLTGIEEVKVEAIAMSKLHNMSCPPYMGHSAAVIFHLIYLS"
     gene            454..2652
                     /gene="speF"
                     /locus_tag="RH288_003751"
     CDS             454..2652
                     /gene="speF"
                     /locus_tag="RH288_003751"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase SpeF"
                     /protein_id="HDV4032765.1"
                     /translation="MSKLKIAVSDSCPDCFTTQRECIYINESRNIDVAAIVLSLNDVT
                     CGKLDEIDATGYGIPVFIATENQERVPAEYLPRISGVFENCESRREFYGRQLETAASH
                     YETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEALFRADLC
                     NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVL
                     FDRNNHKSNHHGALLQAGATPVYLETARNPYGFIGGIDAHCFEESYLRELIAEVAPQR
                     AKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCS
                     PLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMH
                     ASTSPFYPLFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELV
                     DGKPWQSYETAQIAVDLRFFQFVPGEHWHSFEGYAENQYFVDPCKLLLTTPGIDARNG
                     EYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLVRFEKLL
                     ESDAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRV
                     SMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFS
                     ALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRDAQSTLLKGEKL"
     gene            2649..3968
                     /gene="potE"
                     /locus_tag="RH288_003752"
     CDS             2649..3968
                     /gene="potE"
                     /locus_tag="RH288_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HDV4032766.1"
                     /translation="MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
                     VVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVEN
                     PERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSRVTKVDAPVQGMLTIVIIQS
                     GLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            4044..4193
                     /locus_tag="RH288_003753"
                     /pseudo
     CDS             4044..4193
                     /locus_tag="RH288_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            4317..4967
                     /locus_tag="RH288_003754"
     CDS             4317..4967
                     /locus_tag="RH288_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2625 domain-containing protein"
                     /protein_id="HDV4032767.1"
                     /translation="MREMNQLVNTEDSAWPIIQNWLKDATNHTELLPVNKDLAETALY
                     QLQVTTKSPMGALVYGSGGLLIDNGWLRIAGSGHPRLPRDPVSWTQRPEFAGVRALPI
                     ADDVAGGIFALNGGDLGEDTGCVYYFAPDTLNWESLEVGYSEFLQWALSGDLDTFYEN
                     VRWQQWREDVIKLSATEAFTFYPFLWVQSEEARTRKVISLTELWEMQYQMKETFTQ"
     gene            complement(5008..5502)
                     /locus_tag="RH288_003755"
     CDS             complement(5008..5502)
                     /locus_tag="RH288_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032768.1"
                     /translation="MKTNRSLVVIVSLITATLLLTACAQPEQSSLAGDWLLTPKDKTR
                     GLTGSIAVNIAPFRCKTNCRGDNLPDNTRRWQLSGGNEKELTYLHNMSAQEKVGLNPG
                     WQCYTSFFMRVCQGKPGTRPIVNEDYVSESGFFGSMMHVGIIELRRCQSENCQQELKA
                     INTH"
     gene            complement(5716..7356)
                     /gene="pgm"
                     /locus_tag="RH288_003756"
     CDS             complement(5716..7356)
                     /gene="pgm"
                     /locus_tag="RH288_003756"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HDV4032769.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALLADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPQWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(7382..7927)
                     /gene="seqA"
                     /locus_tag="RH288_003757"
     CDS             complement(7382..7927)
                     /gene="seqA"
                     /locus_tag="RH288_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HDV4032770.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSAASQPAAP
                     VTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLD
                     AQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMI
                     EHIMQSMQFPAELIEKVCGTI"
     gene            8112..8876
                     /gene="ybfF"
                     /locus_tag="RH288_003758"
     CDS             8112..8876
                     /gene="ybfF"
                     /locus_tag="RH288_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDV4032771.1"
                     /translation="MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHN
                     IIQVDMRNHGLSPREPVMNYPAMAQDLVDTLDALQIDKATFIGHSMGGKAVMALTALA
                     PDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQ
                     FLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPALFIPGGNSPYVSEQYRDDLL
                     AQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND"
     gene            9016..9309
                     /gene="ybfE"
                     /locus_tag="RH288_003759"
     CDS             9016..9309
                     /gene="ybfE"
                     /locus_tag="RH288_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HDV4032772.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV"
     gene            9449..9979
                     /gene="fldA"
                     /locus_tag="RH288_003760"
     CDS             9449..9979
                     /gene="fldA"
                     /locus_tag="RH288_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HDV4032773.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQISEELHLDEILNA"
     gene            10189..10275
                     /gene="uof"
                     /locus_tag="RH288_003761"
     CDS             10189..10275
                     /gene="uof"
                     /locus_tag="RH288_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fur leader peptide"
                     /protein_id="HDV4032774.1"
                     /translation="MIRIISRANSVTSSNEVNRLVTGQIPHD"
     gene            10268..10714
                     /gene="fur"
                     /locus_tag="RH288_003762"
     CDS             10268..10714
                     /gene="fur"
                     /locus_tag="RH288_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HDV4032775.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK"
     gene            complement(10798..11124)
                     /locus_tag="RH288_003763"
     CDS             complement(10798..11124)
                     /locus_tag="RH288_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032776.1"
                     /translation="MKKLILIAMMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKEKQHQQFADQESVRVLDYQQCLRATQTGNDQAVKADCDKVWQE
                     IRSNNK"
     gene            complement(11174..12580)
                     /gene="chiP"
                     /locus_tag="RH288_003764"
     CDS             complement(11174..12580)
                     /gene="chiP"
                     /locus_tag="RH288_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HDV4032777.1"
                     /translation="MRTFSGKRSTLALAIAGVTAMSGFMAMPEARAEGFIDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKV
                     DYLHSLGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRD
                     KVDDRSVNDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNI
                     FQDERDVKFMVIAPFTIF"
BASE COUNT         3173 a         3127 c         3168 g         3369 t
ORIGIN      
        1 tgatcatttt ttattgatca ccttcatagt tcaaccgtat ttcctggata gaatatcttc
       61 accttcattc acatcaggaa aggtaaatta aatggaaaat aacagccgca ctatgcccca
      121 tataaggcgg acaactcata ttatgaagtt tgctcatcgc aatagcttcg actttcactt
      181 cttcaatgcc cgttagtcta ccgactaagg gcacttcagc gtacaggtct tcctgactct
      241 ctgtattaca ggcatatgcc tgtattccgc agtgctcatt ctctgttaac ccttgtatta
      301 tcagccacct gactggtaag ggtttctgca ttctgaaaaa agcaatctac ctgatttatt
      361 tatcagcggg gtaactttgc ttttttccgg cacgatcgat ttctcattcg agaaattgag
      421 gacctgctat tacctaaaat aaagagatga aaaatgtcaa aattaaaaat tgcggttagt
      481 gattcttgcc cggactgttt taccacgcag cgagaatgta tctacattaa tgaaagtcgt
      541 aatatcgatg tggcggcaat agttttatcg ctcaacgatg ttacatgcgg aaaactcgat
      601 gaaatcgatg ccacgggtta tggcatcccg gtatttattg ctactgaaaa tcaagaacgt
      661 gtacccgcag agtatttgcc ccgtatttcg ggtgtctttg agaattgcga atcgcgacga
      721 gaattttatg gtcgccagtt agaaaccgct gccagccatt atgaaactca actgcgccca
      781 cctttcttcc gcgcactggt cgattatgtc aatcaaggta acagcgcgtt tgattgccct
      841 ggtcatcagg gcggcgaatt tttccgtcgc catccggcgg ggaatcagtt tgtggaatac
      901 tttggtgagg cgctgttccg tgccgacttg tgcaacgccg acgtagcgat gggcgatctg
      961 ctgattcacg aaggcgcgcc atgcattgca cagcaacatg cggcaaaagt gtttaatgcc
     1021 gataaaacct acttcgtttt aaatggcact tcatcttcta acaaagtggt tttaaacgcc
     1081 ctgctaacac cgggtgatct ggtgctgttt gatcgcaata accacaaatc taaccaccac
     1141 ggagcgttgc tacaggctgg tgcaacaccg gtttatctgg aaacggcacg taacccgtat
     1201 ggctttatcg gtggcattga tgcgcactgt tttgaagaaa gttacctgcg tgagctgatc
     1261 gcggaagtcg caccgcagcg ggcaaaagag gctcgtcctt tccgcctcgc tgtgattcag
     1321 ttaggcacct acgacggtac gatttataac gcccgccaag tggtggataa aattggtcat
     1381 ctgtgtgact acatcctgtt tgactcagca tgggtcggct atgaacagtt tattccgatg
     1441 atggcggact gttcgccgct gttgctggat cttaatgaga acgatccggg tattctggtt
     1501 acgcaatctg tgcataaaca acaggctggt ttttctcaga cttcacaaat tcataaaaaa
     1561 gacagccaca tcaaagggca acagcgttat gtaccgcaca aacgcatgaa caacgccttt
     1621 atgatgcacg cctccaccag cccgttctat ccgctgtttg ccgcactgga tatcaacgcc
     1681 aaaatgcatg aaggtgtcag cggtcgtaat atgtggatgg attgtgtggt aaatggcatt
     1741 aatgcccgca aactgatcct cgataactgt cagcatattc gtccgttcgt acctgaactg
     1801 gtggatggta aaccctggca gtcgtatgaa acagcgcaaa ttgcggttga tctgcgcttc
     1861 ttccagtttg taccagggga acactggcat tcttttgaag gctatgcaga gaatcaatac
     1921 tttgtcgatc catgcaaact gttgctgaca accccaggta ttgatgcacg taacggcgaa
     1981 tatgaagcgt tcggtgtacc cgcgacgatt cttgctaact tcctgcgcga aaatggcgta
     2041 gtgccggaaa aatgcgatct taactccatc ctcttcctgc tgactccggc agaagatatg
     2101 gccaaacttc agcaacttgt tgccctgctg gtacgcttcg aaaaactgct tgagtccgac
     2161 gcgccattag cagaagtgct accttccatc tacaaacagc atgaagagcg ctacgccggt
     2221 tataccctgc gtcagttgtg tcaggaaatg catgatttgt atgcccgcca caacgtgaaa
     2281 caactgcaaa aagagatgtt ccgtaaggag cacttcccac gcgtcagcat gaatccgcaa
     2341 gaagccaact acgcctattt acgcggtgaa gtggaactgg ttcgtctgcc ggatgcagaa
     2401 ggccgtatcg ctgccgaagg tgcgcttcct tatcctccgg gtgtgctgtg tgttgttccg
     2461 ggtgaaatct ggggtggtgc tgttctgcgt tacttcagcg ctctggaaga agggatcaac
     2521 ctgctgccag gttttgcacc ggagctgcag ggtgtctata tcgaagaaca tgatggtcgt
     2581 aagcaagttt ggtgctatgt catcaagcct cgtgatgcgc aaagcaccct gttgaaaggg
     2641 gaaaaattat gagtcaggct aaatcgaaca aaatgggcgt cgttcagtta accatactga
     2701 cgatggtcaa catgatgggc tccggtatca tcatgctgcc gacaaagctt gccgaagtcg
     2761 ggacaatctc aattatctcc tggctggtga cagccgtagg ctcaatggca ctggcatggg
     2821 cattcgcaaa atgcggtatg ttcagccgta aatcaggcgg tatgggcggt tatgccgagt
     2881 atgctttcgg taaatccggt aactttatgg cgaactatac ctacggcgtc tcactgctga
     2941 ttgctaacgt cgcgattgct atttcggcgg ttggttacgg caccgaactg ctcggcgcga
     3001 gtttgtcgcc agtgcagatt ggtcttgcga ccatcggggt gctgtggatt tgtaccgtgg
     3061 ctaactttgg tggtgcgcgc attaccgggc aaatcagtag cattaccgtg tggggggtca
     3121 ttattccggt cgtcggtctg tgcattattg gctggttctg gtttagcccg acgctgtacg
     3181 ttgattcctg gaatccgcat catgcaccgt tcttcagtgc ggtaggttct tccatcgcta
     3241 tgacgctgtg ggcttttctt ggtctggagt ctgcgtgtgc gaatactgat gtagtggaaa
     3301 acccggaacg taatgtgcca atcgcggtac tcggcggtac gttaggtgcg gcggtgattt
     3361 atatcgtctc caccaacgtg attgccggga ttgtgccaaa tatggagctg gcaaattcaa
     3421 cggcaccatt tggtctggcc ttcgcgcaga tgttcacgcc ggaagtgggt aaagtcatta
     3481 tggcgctgat ggtgatgtcc tgctgcggtt cgctacttgg ctggcagttc accattgccc
     3541 aggtgtttaa atcttcatct gatgaaggct acttccctaa aattttctcc cgtgtaacca
     3601 aagtggatgc accggtgcag ggaatgttga ccattgtgat tattcagagt ggattggcac
     3661 tgatgaccat tagcccgtcg ctaaacagtc agttcaacgt gctggttaac ctggccgtgg
     3721 tgaccaatat cattccgtat attctgtcaa tggcggcatt agtcattatt cagaaggtcg
     3781 ctaatgtgcc cccctcaaaa gcgaaagttg caaactttgt tgcttttgtt ggcgcgatgt
     3841 atagctttta tgcgctgtac tcatccgggg aagaagccat gctgtacggt tccatcgtga
     3901 ccttccttgg ttggacactg tatggtctgg tatcaccacg ctttgaactg aaaaataaac
     3961 acggttaata aaacaaagta aaaaagggcg attgaatgat cgccctttct gtttgttggc
     4021 aaatagttcg ttatttatgc cgcatccggc agatgtaggg tctaaacgcg atcgaacaca
     4081 gcaactattt gcgtaattat atggggcatc tgcgacaaaa actggaacag gatccggccc
     4141 ggcctcgcca ttttattact gaaaccggta ttgggtatcg gtttatgctt tgaaaaaagt
     4201 ggcaatgtat ggataaagtc attttttatt caaatataag gaacttaata tttaaaaaat
     4261 gttccataca attcctcatc ataaatgaca ccgtagcaca caaggagcaa gtagcgatgc
     4321 gtgaaatgaa tcagttagta aatactgaag attcagcctg gccaataatc cagaactggt
     4381 taaaagacgc cacaaaccat accgaactct taccggttaa taaagattta gccgaaaccg
     4441 cactttatca attacaggtg acaacaaaat caccgatggg tgcgcttgtc tatggctccg
     4501 gaggtctgct gattgataat ggttggttac gcatagcagg atctggtcac ccccggttgc
     4561 cacgagatcc agtaagttgg acacaacgcc ctgaattcgc aggcgtgcgg gctttaccca
     4621 tcgctgacga tgtcgcaggg ggaatttttg ctcttaatgg tggcgatctt ggggaagata
     4681 ctggctgcgt ttattatttt gcgccagata cgctgaattg ggaaagtctg gaagttggat
     4741 attctgagtt tcttcagtgg gcattatccg gtgatttaga taccttctat gaaaatgtac
     4801 gatggcagca atggcgagaa gacgtaataa aattatcggc aacggaagcc ttcacgttct
     4861 accctttctt atgggtacaa agtgaagaag caagaacaag aaaagttatt tcgcttactg
     4921 aactctggga aatgcagtat caaatgaaag aaacattcac gcaataagac atgttcaggt
     4981 ccgggtttca ttcccggact cactatttta atgtgtattt atcgctttca attcttgctg
     5041 gcaattttct gactggcagc gtcgtaactc aataatcccg acatgcatca tcgagccaaa
     5101 aaatccgctt tcgctgacat aatcctcatt gactatcggt cgagtgccgg gcttgccctg
     5161 gcaaacccgc ataaaaaatg aggtgtagca ttgccaaccg ggatttaaac cgaccttttc
     5221 ttgtgctgac atattatgaa gataagtaag ttctttttcg ttcccgcctg acaactgcca
     5281 gcggcgggta ttatcaggta agttatcacc acggcaattt gtcttacacc ggaaaggtgc
     5341 aatatttacc gcaatgctac ccgttaatcc tctggtttta tctttagggg tcagtaacca
     5401 gtcgccagct aatgatgatt gttcaggttg ggcgcatgca gtcagcagta atgtggcggt
     5461 aattagtgac actatgacga ccagactcct gttggtcttc attgggattt ccttgagcta
     5521 ctcagtttgt tgacaaagtg ttcgttgttt ttgccggatg cggcgtgaac gccttatccg
     5581 gcctacaaaa tcgcttaaat tcaatatatt gcaccatcct cgtaggcctg ataagcgtag
     5641 cgcatcaggc aattctgtgt ttgtcatacg taaaaaaggg cgatcttgcg accgcccttt
     5701 ttttattaaa tgtgtttacg cgtttttcag aacttcgcta acaatctcaa ccgcttcttt
     5761 ctcaatctgc ttgcgatgtt cttcaccgag gaagctttcg cagtagatct tatatgcgtc
     5821 ttccgtgcct gacggacgcg cggcgaacca gccgttgtca gtcatcactt tcagaccgcc
     5881 aatagaagca ccgttgcccg gagcagcagt caggcgcgcg gtgatcgggt cacctgccag
     5941 ggtgctggcg ctcaccattt ccggagacag cttagacagc gccgcttttt gtgcggaagt
     6001 cgcagctgcc tgcaaacggt tgtagctcgg cgcaccaaag cgttttgcca gttcgttgta
     6061 gtgttcctgc gggttcttac cggtgacagc ggtgatttcc gccgccagca gacacatgat
     6121 gatgccgtct ttgtcggtgg accacggcgt gccgtcgaaa cgcaggaagg aagcccctgc
     6181 gctctcttcg ccgccaaagc cgaagctgcc gtcgaacaga ccatcaacaa accatttgaa
     6241 acctaccggg acttctacca gcttacgacc caagtcattg accacacggt cgatcatcgc
     6301 agaagaaacc agcgttttac caacggcaac atctttgccc cactgcggac gatgctggaa
     6361 caggtaattg atcgccaccg ccaggtagtg gttcggattc atcaaacctg ccggagtgac
     6421 gataccgtga cggtcataat ccgggtcgtt agcaaacgcc agatcgaact tatcacgcag
     6481 tgccagcagg cccgccatcg cacactcgga ggagcagtcc atacggatcg cgccgtcttt
     6541 atcaaggtgc ataaagcgga aggtttgatc gacctgatcg ttaacgatag tcaggttgag
     6601 gttgtaatac tcgccaatgc gcttccagta ttcgataccg gaaccgccca gcggatcaac
     6661 gccaagcgtc aggcccgctt tctgaatcgc cgccatatca acgatatcgg ccagcccttc
     6721 cacgaacggc tgcaccagat cctgctcttt cacatgaccg gatgccatcg cttcgtcgag
     6781 ggagatacgc ttcacgcctt tcaggccatc ggccagcagt gcgttggcac gatcttccac
     6841 cactttagtg acgttggtat cagccgggcc accatttggc ggattgtact tgataccacc
     6901 atcttccggc gggttatggg acggtgtaat aacgataccg tctgccagcg ggccaccttt
     6961 tttattgtga accaggatgg cattggaaac ggcaggcgtc ggggtgaagc cattgttttc
     7021 ctgcacaata acatctacgc cgttcgctgc cagcacttcc agaacggaaa taaatgcagg
     7081 ttcggacagg gcgtgagtat ctttacccac atagcaaggg ccagtgatac cgtttttcgc
     7141 acgttcttca gcaattgcct gagcgatcgc cagaatgtgc ggctcgttaa agctgtggcg
     7201 cgctgcactg ccacggtgac cggaagtacc gaatttcacc gcgtgctccg cattccctgc
     7261 ttctggtttc agtacataat attgcgccgt cagttgggcg acgttaatca aatcactctg
     7321 ttgtgcaggt tggcctgcac gattgtggat tgccattgct ttgtcctttg tctgcaacgt
     7381 tttagatagt tccgcaaacc ttctcaatca attccgccgg gaattgcatc gactgcatga
     7441 tgtgttcgat catgctgcat ttacggccgg tgttggtgtt ggtgatcacc caatacggcg
     7501 tgcctggcac atgtttcggc ttggtctgat taccattttt cagcagcgtt tgttcatctg
     7561 ccgcaaagta aacgcgtgta cgaccgtgca acgattccgt tgcttcggca aacgcctggg
     7621 cgtcaagaga atatagtgta gacaacagca gcataaagcg attgaccgct cgcttttgct
     7681 ctgcgtattc gtccgaaagc agaagttcac gcattgcgcg aaccttgtct ttaatcgttt
     7741 tgaccggctt cgcttcgacg atagcaggtg acgcaacgcg aacctctttc gtcaccggag
     7801 cagcaggctg tgatgcggcg gaaaatttca acatacgccg taaaatgtcg gatgcgctct
     7861 cgccgatatg cttagtgtgg ctggcaatat agctgtagag ttcatcatca acttcaatcg
     7921 ttttcatctt aatccagtgc agtgtcttag ctgaatacaa gtcgccagga gtatatgaat
     7981 aaatcccggc agcggatagc gtcaagcctg gcttgcagaa aaactcggaa taaaccttat
     8041 ttgttgcagc cctgtggcac aatggtcaac ataataccct aacccgacaa cgcgaaaaaa
     8101 agaactttgc catgaaattg aatatccgcg cgcaaactgc acaaaaccag cacaataatt
     8161 ctcccatcgt tcttgtccat ggtctgtttg gtagcctcga caaccttggc gtactggctc
     8221 gcgatctggt aaacgatcac aatatcatcc aggttgatat gcgtaaccac ggtctttcac
     8281 cgagagagcc ggtaatgaat tacccggcga tggcgcagga tcttgttgat accctggatg
     8341 cactgcagat cgacaaagca acatttatcg gtcactccat gggcggtaaa gcggtaatgg
     8401 cacttactgc actggccccc gatcgcatcg ataaactggt ggcgatcgat atcgcaccgg
     8461 tcgactatca cgtacgccgt catgatgaga ttttcgcagc tatcaacgcg gtcagtgaat
     8521 cggacgcaca aactcgccag caagcagcag caataatgcg ccagcatctt aatgaagaag
     8581 gggtgattca gtttctgttg aaatcttttg ttgacgggga gtggcgcttt aacgtgccgg
     8641 tattgtggga tcagtatccg catattgtgg gttgggagaa aatcccggca tgggatcacc
     8701 ctgccctgtt tatccctggt ggtaattctc cgtatgttag cgagcagtac cgtgatgatt
     8761 tactggcaca atttccacag gcacgggcgc atgtcattgc aggcgcgggt cactgggtcc
     8821 atgctgaaaa accagatgcg gtattacgcg ctatccgtcg ctatctcaat gattaacgca
     8881 actgattaaa aacccagcgt ccgcgtcgct ttccgcgcgt gggcgttggc gtgactcatc
     8941 gcgctgatgt attatggcgc gctatccatc cgggcagagg cctggctgat tgtttccccc
     9001 gaagtcacca agatcatggc caaagaacaa acggaccgta cgacattaga tctgttcgcg
     9061 cacgagcgtc gaccgggacg accgaaaact aatccgcttt cgcgcgatga acagctgcgt
     9121 attaataaac gcaaccaact aaaacgcgac aaagtacgtg gccttaagcg tgtcgaactg
     9181 aagctgaacg cggaagctgt cgaggcgctg aacgagctgg cggaatcgcg caatatgagc
     9241 cgtagcgaac tgatcgaaga gatgttaatg cagcaactgg cggcgctgcg tagtcagggc
     9301 atcgtttaaa tttccacttt catgtagcac agtgtgcagt cctgctcgtt tgctgattcc
     9361 gcaagactgc ctgttctgct atgattgcct ttatccgtgg gcaattttcc acccccattt
     9421 caataagttt caagaggtta tttcactcat ggctatcact ggcatctttt tcggcagcga
     9481 caccggtaat accgaaaata tcgcaaaaat gattcaaaaa cagcttggta aagacgttgc
     9541 cgatgtccat gacattgcaa aaagcagcaa agaagatctg gaagcttatg acattctgct
     9601 gctgggcatc ccaacctggt attacggcga agcgcagtgt gactgggatg acttcttccc
     9661 gactctcgaa gagattgatt tcaatggcaa actggttgcg ctgtttggtt gtggtgacca
     9721 ggaagattac gccgaatatt tctgcgacgc attgggcacc atccgcgaca tcattgaacc
     9781 gcgcggtgca accatcgttg gtcactggcc aactgcgggc tatcatttcg aagcatcaaa
     9841 aggtctggca gatgacgacc actttgtcgg tctggctatc gacgaagacc gtcagccgga
     9901 actgaccgct gaacgtgtag aaaaatgggt taaacagatt tctgaagagt tgcatctcga
     9961 cgaaattctc aatgcctgat gtgatgcggc gtagactcat gtctacgccg tattaataga
    10021 taatgccaat caaaataatt gctacaaatt tgtaactttt gctgttgtac ctgtacaatg
    10081 tcccggtgtt caagtggcct tgccgttgta aatgtaagct atgccacgtt tttattaaca
    10141 atatttgcca gggacttgtg gttttcattt aggcgtggca attctataat gatacgcatt
    10201 atctcaagag caaattctgt cacttcttct aatgaagtga accgcttagt aacaggacag
    10261 attccgcatg actgataaca ataccgccct aaagaaagct ggcctgaaag taacgcttcc
    10321 tcgtttaaaa atcctggaag ttcttcagga gccggacaac catcacgtca gtgcggaaga
    10381 tttatacaaa cgtctgatcg atatgggtga agaaattggt ctggctacgg tatatcgcgt
    10441 actgaaccag tttgacgacg ctggtatcgt cacccgccac aattttgaag gcggtaaatc
    10501 cgtatttgaa ctgacacagc aacatcacca cgatcacctg atctgcctcg actgcggcaa
    10561 ggttatcgaa tttagtgatg attccatcga agcgcgtcag cgtgaaattg ccgcaaaaca
    10621 tggcattcgc ctgactaacc acagtctcta tctttacggt cactgtgccg aaggcgattg
    10681 ccgcgaagat gagcacgcgc acgaaggcaa ataagccagc ctgaacgaga aaagccaacc
    10741 tgcgggttgg cttttttatg caagggaaat aagaaaagcg agagttacag ctctcactta
    10801 tttgttatta ctgcgaattt cctgccagac cttatcacaa tcggctttca ccgcctgatc
    10861 atttccggtt tgcgttgcac gcagacactg ctgataatcc agtacgcgga cactttcctg
    10921 gtcggcaaac tgctgatgtt gtttctcttt cttcagcacg tttaacacgc tctggcaggc
    10981 ttcaattttt tccggcgaac cttgcgcggt gttgatacag gcgctgtatg cctctttcag
    11041 acggctgtct tcctgtggtg cggttgattg cgcacaagct accagccccg atgccatcat
    11101 ggcgatgaga atcagttttt tcatagcaaa ttcctcaaac gtgcggcagg cacaaaacct
    11161 gccgcgtcgg gcatcagaag atggtgaatg gtgcgattac cataaatttt acgtcacgct
    11221 catcctggaa gatgttgccg taaccaccgc cccagcttgg gatgtcggag tggttgtcgt
    11281 attcggtgaa gtgcagtttg aacatcgtgc ctttggcgcg accgtcctga atggtataga
    11341 ccgcatccag gctgtatgca gactcttcaa tagtccggtt tttgtcgtag tacgcatccg
    11401 gattgctctg ccaggtcgca ggtttagcat cccatgcgta aacgtaggaa gcgccgatgg
    11461 cgaagcctgg aagattccag tttttcaggt catacatcgc accgaagaag actgcttttt
    11521 cgccgttggc gttgaagtca gaacggttgt cccaccagat atccaggcga ccgtttgagg
    11581 aagcgtaggt tggagtcata cgttgcagga agtatccctg ctgaccgtca gccttaaccc
    11641 aggtgccttc gaggcgcaaa tccactacgt cagccgcccg gtaaccaaag gtcaacgcct
    11701 gcagccaggc ggtgccgtca taaaggtcgt tgacgctgcg atcgtcaact ttatcgcggg
    11761 taccgtagaa ctggtagctg gtggttaacg ggctaccggc gatatcaaat ttgtagctgg
    11821 ctttggcaaa atattgatcg atataccctt ccgcctgacc aaaagccgct tccagtacga
    11881 agttattttt gaagtcgtat ttcgccccaa gggagtgcag ataatcaact ttggtggttt
    11941 tatcgttctg ataaaactca tccatttcca gatgccacgg cgctttgtat tcgttggtcc
    12001 acatgtagga gaaactcaac gcaccggcat cgccgtaatc aaaattcgct ccggcttccg
    12061 caccctgata agtacccggc ataaagctcc agtgaggcgc taacagcgtc tgaccggttg
    12121 gctgaatata acctgccctc gcccaaaccg gaccgtattt aaatttggcc gctgctttat
    12181 acaggcttat accgcttttg tcgccggacc agtcttcgtc ataggcttta ttactttttg
    12241 aaaacgcgat ttcgttcggg tgagagctgt cgccgttttc cgccatttca atcgccgtaa
    12301 acgcggcaat atcaaggccg aacatatcag cagcataacc agactgaaaa tcgaggttgg
    12361 cattccaggt ggagtgagaa aggttggttt tgtatttgtc gccgtcggta acatctttac
    12421 ggtcgcgttc acgctgccag taatatatac cgccggttaa ggttgaatcg tcgatgaatc
    12481 cttcggcgcg agcctccggc attgccataa agcccgacat tgctgtaaca ccggcgatag
    12541 ccagcgccag cgtactacgt ttgccactaa acgtacgcat gggttaatcc tctttgacgt
    12601 ataaattgct gcaccaaagg tgaacagcga aaaaataaaa attaaaaaag tagcgttgag
    12661 aaaagtctcg ctgactacag gaacagacta tttttcgcga cgcgaattat caatctcttt
    12721 ctgtaaccag aatgtaagaa catgagcaac cgcacatatt ttgatgattt ttgttacaag
    12781 gcttaagttt gcggttgaaa ggcttgcaga agaataaaag cgtgaaattc cagcaag
//
LOCUS       DAPHKZ010000129        12801 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.129, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000129 DAPHKZ010000000
VERSION     DAPHKZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12801
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.129"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..877)
                     /gene="yhaJ"
                     /locus_tag="RH288_003765"
     CDS             complement(<1..877)
                     /gene="yhaJ"
                     /locus_tag="RH288_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HDV4032778.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIV
                     TEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKSWCLREIP"
     gene            982..1683
                     /locus_tag="RH288_003766"
     CDS             982..1683
                     /locus_tag="RH288_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HDV4032779.1"
                     /translation="MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLN
                     QEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYS
                     EHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGAMGSLQLRQQVW
                     LHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITL
                     VADSPLRALLIDLPV"
     gene            1706..1870
                     /locus_tag="RH288_003767"
     CDS             1706..1870
                     /locus_tag="RH288_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032780.1"
                     /translation="MSKKLAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAE
                     TRLAEDEATA"
     gene            complement(2004..3314)
                     /locus_tag="RH288_003768"
     CDS             complement(2004..3314)
                     /locus_tag="RH288_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDV4032781.1"
                     /translation="MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAEL
                     EGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQ
                     AIADAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDG
                     VVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEG
                     LSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAA
                     GMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR"
     gene            complement(3342..4673)
                     /locus_tag="RH288_003769"
     CDS             complement(3342..4673)
                     /locus_tag="RH288_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026203.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HDV4032782.1"
                     /translation="MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMS
                     IGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSV
                     ISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
                     VLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLV
                     KNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFF
                     YAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFG
                     VYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTS
                     ICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS"
     gene            complement(4948..6312)
                     /gene="tdcG"
                     /locus_tag="RH288_003770"
     CDS             complement(4948..6312)
                     /gene="tdcG"
                     /locus_tag="RH288_003770"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDV4032783.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSH
                     IVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGA
                     HIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEELLSKTYYSVGGGFIVEEEHFGLS
                     HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHD
                     GIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISG
                     AEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(6384..6773)
                     /locus_tag="RH288_003771"
     CDS             complement(6384..6773)
                     /locus_tag="RH288_003771"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enamine/imine deaminase"
                     /protein_id="HDV4032784.1"
                     /translation="MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPA
                     DVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATY
                     PTRSCVQVARLPKDVKLEIEAIAVRSA"
     gene            complement(6787..9081)
                     /gene="tdcE"
                     /locus_tag="RH288_003772"
     CDS             complement(6787..9081)
                     /gene="tdcE"
                     /locus_tag="RH288_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-ketobutyrate formate-lyase/pyruvate
                     formate-lyase"
                     /protein_id="HDV4032785.1"
                     /translation="MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGD
                     ESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIV
                     GLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPD
                     MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDL
                     EATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDG
                     EYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAL"
     gene            complement(9115..10323)
                     /gene="tdcD"
                     /locus_tag="RH288_003773"
     CDS             complement(9115..10323)
                     /gene="tdcD"
                     /locus_tag="RH288_003773"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HDV4032786.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAF
                     LSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITD
                     EVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
                     WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLI
                     RRLVMEHLAVLGLEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHL
                     GKVNAPAEFA"
     gene            complement(10349..11680)
                     /gene="tdcC"
                     /locus_tag="RH288_003774"
     CDS             complement(10349..11680)
                     /gene="tdcC"
                     /locus_tag="RH288_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
                     /protein_id="HDV4032787.1"
                     /translation="MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRA
                     GFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITF
                     LYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
                     VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIM
                     VFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLF
                     TLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGH
                     YLGTLEGLNGLVLKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAM
                     GAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF"
     gene            complement(11702..12691)
                     /gene="tdcB"
                     /locus_tag="RH288_003775"
     CDS             complement(11702..12691)
                     /gene="tdcB"
                     /locus_tag="RH288_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HDV4032788.1"
                     /translation="MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAA
                     SFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA"
BASE COUNT         3255 a         3511 c         3072 g         2963 t
ORIGIN      
        1 tgggaatttc ccgcagacac caggatttcg cttcccccat actgtcacga cgccaggcca
       61 taataatatc gatctcgctg gtcgattccg ggctgacgac acgcaaccgc ccttccgcaa
      121 tatctttttc gaccatagga tacggcatcg tcgccacgcc aagccccgcc agtaatgcct
      181 gacgtttatc ttcaatcgtg ctcaccgtta agcgcggctg tttgtccagc agctgtacgg
      241 tcaacaccgg gcgctcacga gcggtatccg ccaccgcaat tccacgatat ttcacacgcg
      301 tcacttcaga taacggttcc ggctcctgat gaatcgggtg atcaggcgcg gcaacgtaga
      361 cgttcattaa cgtatagagc ttgcgcgagt tgatctccga cgaggaacga aaatgcatat
      421 ccggcgcgat aacaatatcc gcccgcccct gctccagccg ttcccacgcc cccgccagca
      481 cttctgtgat gattgccagt tgggtattgg cttttgccgc cagtttgtcg attaacggga
      541 aaaaggcagg tgtcggtacc agcgcttcgg tcacaatggt gagatgcgtt tcccaaccgc
      601 gcgcgagagc ttccgcatca gtagtcagtt tatctgcggc ttccagcaaa acgcgccctc
      661 gctccaacaa catcctcccg acattggtga atttggtacg atggcccgag cggtcaaaca
      721 gcaccacatc cagctcttct tccagttttt gcatggtgta gctaagtgcg gaaggcacgc
      781 gtcccagctc atccgccgcc gccgcaaaac tgccccggcg atcgatcgca tccataaccc
      841 gtagtgcttc cagcgttaat gccctttctt tggccatttc gttctcattc aggaaatttg
      901 aacataccgg gcagaatatc tggctaacaa tgtagcgtcc agccccttac cataaaagga
      961 agtaaagaga ggtcaagaat tatgattact acccgaactg ccaggcagtg tggacaagca
     1021 gactacggat ggttgcaggc ccggtatact ttttcctttg gacactactt cgacccgaaa
     1081 ttgttaggct atgcctccct gcgtgtgctt aaccaggaag tgctggcccc aggtgccgcc
     1141 tttcagccgc gaacctatcc caaagtcgat attttaaatg tgattctgga tggagaagca
     1201 gagtatcgcg atagcgaagg caatcatgtt caggccagcg ccggagaggc gttgctgctc
     1261 tctacccagc cgggtgtcag ctatagcgaa cacaatctca gcaaagacaa accgttaacg
     1321 cgaatgcagc tttggctgga cgcctgcccg cagcgagaga atccgctgat tcaaaagctg
     1381 gcgcttaata tgggcaagca gcaattaatc gcctcgccag agggtgcgat gggaagcctg
     1441 caattacgcc agcaagtgtg gctgcaccat atcgtgctcg acaaaggcga aagtgcgaat
     1501 ttccagttgc atgggccacg cgcgtatttg caatcgattc acgggaaatt tcatgcgctt
     1561 acgcatcatg aagagaaagc ggcgctgacc tgcggtgatg gggcgtttat tcgtgacgag
     1621 gctaacatta cgctggttgc cgattcccca ctgcgcgctt tgctgataga tttgcctgtc
     1681 tagttgtttt tacagggaga tgatgatgag taaaaaattg gccaaaaagc gccagccggt
     1741 gaagcccgtg gtggcgaaag aacctgctcg caccgccaaa aattttggct atgaagagat
     1801 gttgagcgag ctggaagcta tcgtcgcgga tgctgaaacg cgtttagccg aggatgaagc
     1861 taccgcgtaa agacaggttg ccggatgcgg cgaaaacgcc ttatccggcc tacaaaatcc
     1921 aacaacatta acgaattaaa caacccgtag gccggacaag atgcgccagc atcgcatccg
     1981 gcacgatccc caaaacctgg cgtttatctg gccttgctcg ccataatctc gataatctgc
     2041 cgatccgttt gctgcatcga atggcttgct aacgcacaca ggttggcaat cgactgctca
     2101 acatcatgcg ccacaatccc ttcattgccg gtcacggcgg tatcatccag cgccattaac
     2161 accgctttcc acgcagccga agcactggtc gaaaccttca tcgcgcagct gttcgacgca
     2221 ccatcgcaaa tcatgccgct gacatcgccg atcatactgc tgatcgccat cgagatggtt
     2281 tcataacgcc catccaccag ccatgccatc ccggcggcgg cccccattgc tgcggtcgtt
     2341 gcggcacaca gcgcagacaa acgcggtaac tggttatgga tgtaaattgc gctcaaatgc
     2401 gaaagcatca gcgcacgcgc cagccgttca tcatccgctc cgaagtgttc tgctaccacc
     2461 accacaggca ttgttgcggt aatcccctgg ttacccgagc cggagttact catagccgga
     2521 agcgtagcgc cgcccatacg cgcatcggat gccgcgctgg tacgaatcac aatggatgaa
     2581 gagagatctt tcgccagcaa accgcgctcg cactgttttt ccagcgtcgc gccaatatgc
     2641 agcccccact taccgctcaa accttcctgc gataacgcac aatttagctt cgcggaatcg
     2701 agaataaagc ggatcgccgc aaacgggact tcattgacga acttcaggat ctcagccagc
     2761 gtcgttctgg aaagcaccgt cagcggagac tcttgctcgc cctctgccac acacgcctgc
     2821 tgggtaaaca ccacaccatc gtgcgtctcg atatgcacaa tgttggtatg cccgccgacg
     2881 atggtgacac acgcccactt ctcaccgttc cagactttgg cgcgtgagaa gaggatttca
     2941 tcgcaaggtt cctggatctt aacggagact ttccccgccg ccagcagtgc tttggcatcg
     3001 gcaattgcct gcgctgttgc gtctttcagc acttccagcc cggcgttggc atttccacct
     3061 aacgccccca gcgccgccgc aatcggcagc cccaccattc ccgtgccggg aacggtgacg
     3121 cccagaccgt tcttcatcag atttggcgaa acccaggctt ctacacgttc aaccggacct
     3181 tccagttctg ccgcagcaac cgccgccgcc agcgccagtg aaatcggttc agtacatccc
     3241 agcgccggtt ttacttcctc ctgaacggcg aggatgtaac gctgccataa cggatttaaa
     3301 gtcgaatcaa acatattaaa aaccttaaaa tttcaggtaa atcaagaaaa tgccaggaac
     3361 ggagaaacac acagcaacaa accagtgacg ataatcaggt acagagacat ccctttgtat
     3421 ttgtgcaatg ctggtacttt gtaaaccagc cacgccggga tcaggcaccc taccatgccg
     3481 aaaatcgggc tacagataga ggtgaagctc aacaccggtg cgttcagtac gatggcgctc
     3541 caggccagca aaatggcgaa aatcatgatg ccgcgctgaa cgagattttc gttaatcttc
     3601 tcggcaggca tcttgcgacg caggatgttc attacgatcc cttgcgttgc ttcgcgaaag
     3661 cctaaataga cgccaaagaa tgcagtcatg acagcaaaga tattgagaat gacgctgacc
     3721 actttcaccc acgctgcgcc gtcaccgcta ataaactgtg cggcaatcgc cagcgcggaa
     3781 atattctgct cataggcttt taccgcttcg tcatgtccca tcgccagcgt gaacgacacg
     3841 gcgtagaaaa agacggtgac aaacaaaatg ccaaacgcga tattcattgc ccgcaatgct
     3901 ttatgccgcg ccacttcaat tgatttttcc cgcgagcgat aagagatcac catcggactt
     3961 aacgtctgga taaacagaat cgacgtcagg gtaaacggca gcgtaataat ggcgtttttc
     4021 accagcagcc ccagcggcgg tagcgaaccg acgttataca gatgccacat tcccaccatc
     4081 gacacgccca gcgccgcgac caccagcagc ttggtcagca ccatgccggt cgaaattttg
     4141 aataacaatt tctcgccgcg tgaggagatc gccaccagaa tgcaaatcag taccagacca
     4201 taaaagggac tgtctgacag caacccttcc gtcacgccga aggtatgcag gtaggaagca
     4261 ctatcgttgg tgatggcggt ggaatagacg aacatccaaa tcaccagcat tacgaaatag
     4321 agcgcaccta acaggatgcc ccagttttta cctaaataac cgctaatgac gctcgggtaa
     4381 tctttacatt ctggtgattc tgccagcgta ttaataaaca atcgctgaaa cagatacatt
     4441 gccgggtaac caatcaccga tgagagcaaa aatacccaca atcccatcaa accgacctgc
     4501 accgggagaa aaacaatccc cgcgccaatc gccatcccga tactcataat cacccagccg
     4561 gtgtcagtac tgtcgaattt gatcgcttct cgccactcgc tctcactcat tccagcacga
     4621 cccgccgggg tcgaagcgtc tgcaatgacg cctttattcg atgcaatttc cataatttct
     4681 cgctcaatat tttgtagggc ttattatttt tttccgagcc gcatcaaggc gatatgcggt
     4741 ctacgttttt gcaggcgagt tattagaata aagaaatgat acgcgcgagg tcagagaaaa
     4801 tcttcacaat caagactttg aaataacgga gatggataag aattttctac taaattaatc
     4861 gcaggagaat attcattctc tatttgcggc agatcacaaa aaaaaggtgc acatttgtgc
     4921 acccaaggat gaaagctgac agcaatgtca gccgcagacc actttaatgg ccagtcctcc
     4981 gcgtgatgtt tcgcggtatt tatcgttcat atctttgccg gtttcataca tcgtctcgat
     5041 cactttatcg agtgaaacac gcggtgccga ggtgcggcgc atcgccatcc gcgcggcgtt
     5101 tactgctttc acggcattaa tggcattacg ttcaatgcac gggatttgta cctgtccggc
     5161 aaccggatcg caggtcagcc caaggttatg ctccatcgcg atttccgccg cattgcatac
     5221 ctgcgccgga ctgccgccca gtagttcagt taaccctgcc gccgccattg aacaggccac
     5281 gccaatctcc ccctgacagc cgacttccgc gccagagatg gaggcgttca ttttatacag
     5341 cgcgccaata gcccccgcgg ccagaaaata gcgggcaatt gaccgctcgt ttaccggacg
     5401 acggaactta tcgtaataag ccagtactgc cggaataatg ccgcacgcac cgttagtcgg
     5461 tgccgttacc acgcgcccgc cagctgcgtt ttcttcacta accgccagcg cgtacatgtt
     5521 gatccagtcg atgacattca tcggatcgtt agagatgtta tcgctggaaa ccagctgacg
     5581 acgcagcgct acggcacggc gcggcacatt gagcggacca ggcagcacgc cttcagtgtt
     5641 catcccacgt tcaataccgt catgcatcac ttgccagata cgggcaaaac cggcgtcaat
     5701 ttccgctttg ctgcgcagcg ctagctcgtt gtgcatcatc agaccagata tagacaggcc
     5761 gttgtaatca cacattttca gcagttcacc tgctgagtgg aaatcgtaag gtacggacgt
     5821 ttcgacatcg tgcgacaggc cgaagtgttc ttcttcgaca ataaacccgc cgccgacaga
     5881 gtaataggtt ttacttaata gctcttcctg tcccttccag gcagtgatcc gcattccgtt
     5941 ctcatggcga ggcaacattt cgggatggaa gataatgttc tttgctacag gaaaatcaac
     6001 aatatgcgca ccagatgcca ctggcagccg cccgctgcgc gttactaact ctataaatgc
     6061 agggatctca tcaatgacaa catcctgcgg actgtttcct gccagtccca tgatgatggc
     6121 gacatccgtg gcatggcctt tgcccgtcag tgacaacgac ccgtacagat cgaccacaat
     6181 atggctcgtc gcggttaata agccgctact ttccagccga tcaataaaac tttttccggc
     6241 attcattggc cccacggtat gcgaactgga gggaccaatc ccaattttga aaatatcgaa
     6301 tgcactaatc atatccacac cctcggattg ccgttcagtg aagtggagcg gaacgacctt
     6361 acgaccgtcc cgctcacgag gctttacgca ctacgtactg cgatggcttc aatttccagc
     6421 ttcacatctt tcggcaaacg cgcgacctgc acacagctcc gggtcggata ggtcgcctga
     6481 tgctcatcga agaactgctt atagacttcg ttgatggtgg caaaatcatt cagatcggtg
     6541 ataaacacgg tcatcttgat gatatcgccc acgctcagcc cggcagcaac cacgatcgct
     6601 ttgacgtttt cgaggcttaa acgcgcctga tcttgcacat cagccgggat ctcaccggtc
     6661 tgtgggcaaa ccggtatttg cccggaggtg aagaccatgc tgcctaaatc aacgccctga
     6721 acataagggc cgattgcgcc tggggcacgt tgcgtttcga taatcttttt catacatcct
     6781 ccggcgtcag agcgcctggg taaaggtacg tgaaataaca tcctgttgct gttcacgggt
     6841 cagtgcgttg aagcgcacgg cgtagccaga gacacggatt gtcaggttag gatatttttc
     6901 cgggtgctcg atggcatcca gcagcatttc ccgattcatt acgttgacgt tgaggtgttg
     6961 accgccttcg acatccgctt cgtggtggaa atacccatcc agcaggccga caaggttggt
     7021 tttacgtact ggatcttctt tgcccagcgc cgcaggaacg attgagaagg tgtacgagat
     7081 cccatctttg gcgtaggtga acggcagttt cgccaccgac gtcaatgagg ccacggcacc
     7141 tttgcggtca cgaccatgca tcgggttagc gcccggcgcg aacggtgttc cggcgcgacg
     7201 accgtccggc gtattaccgg ttttctggcc gtacaccacg ttagaagtga tagtcagaat
     7261 cgactgggta gggacggcgt tgcgataggt tggcagcgct ttaattttct tcataaagcg
     7321 ttcaaccagg tcgcaggcaa tgctgtctac gcgctcgtcg ttgttgccgt actgcggata
     7381 ttcaccgtcg atttcaaagt ccaccgccag gccgttttcg tcacggattg gtttcacgcg
     7441 ggcatatttg atggcagaca gggagtccgt cgccaccgac aggcccgcga tgccgcatgc
     7501 catagtgcga tagacatcac gatcgtgcag cgccatcagc gaagcttcgt agctgtactt
     7561 gtcgtgcatg tagtgaatga tattcagcgc gctgatgtac tgcaccgcca gccagtccat
     7621 gaagtgatcg aggctgtcca tcactttgtc gtaatccagc acgtcgtcca tcagcggtgc
     7681 tgttttcggc ccgacctgaa tcttcagctt ctcgtccacc ccgccgttaa ttgcgtagag
     7741 cagcgttttc gccaggttag cgcgtgcacc aaagaactgc atttgcttac caatcaccat
     7801 tgggctgacg cagcaggcaa tcgcgtaatc gtcgctgttg aagtcagtac gcatcagatc
     7861 gtcattttca tactgcaagg aagaggtgac gatcgacacc tgcgcggcat attttttgaa
     7921 ggcaatcggt aattcttccg accaaagaat ggtcaggtta ggttccggtg ccggccccat
     7981 agtgtgcagg gtgtgcaaat agcggaagga gtttttggtc accagcgtac gaccgtccag
     8041 ccccatcccg ccgatcactt ccgtcgccca gattgggtcg ccggagaaca gcgaatcaaa
     8101 ttccggtgta cgcaggaagc gtaccatacg gatcttcatg atgaagtgat cgatcagttc
     8161 ctgtgcctgc tgctcattga gtacgccagc tttaaagtcg cgctcaatgt agatatcgag
     8221 gaacgatgcc gtgcggccca gcgacatcgc gccgccattt tgcgatttca ctgccgccag
     8281 ataagcgaag tagagccact gcaccgcttc ctgcgcattc tgcgccgggc gagagatatc
     8341 aaagccatat ttcgccgcca tttcctgaat ctgcaacagc gcatgacgat gctctgccag
     8401 ctcctcacgc agacggatgg tggcttccag atcctcgcct ttttccagac gagactggag
     8461 atcggcaaat tgcagttcgc gctcacgtac cagataactg atgccataca gcgctacgcg
     8521 gcgatagtca ccgataatgc gcccacggcc atagccatct ggtaaaccgg tcagcacgcc
     8581 agatttacgg cagcgcagca tatccggtga gtaaacatca aatacgccct ggttatgggt
     8641 tttacgcaga tcggtaaaca gatattcaaa ttcactgtcc atttctcggc cataggcgtg
     8701 gaatgaactt ttaatcatat taatgccacc gaacgggtgt agcgcacgtt tcaacggcgc
     8761 atccgtttgc aggccaacaa ttttttccag cggctggtta atatatcccg catcatgagc
     8821 ggtaattgtg gtggcaatat tggtatcgaa atcaaccggc gcgtgggttg cattttcgat
     8881 acggatgcct tccattactt tttcccacaa ttccgtggtg gcaggcgtcg cttcggcgag
     8941 gaaagattca tcgccttcat acggtgtata gttatgttga ataaaatcgc ggacattaat
     9001 ttcgtttttc cagtccgtac ctttaaagcc aagccatgcg tcggcgtaca gcttatcgct
     9061 ggtatcaata tctaccttca tgaaaaataa tctctctaca atacttcaac taaattatgc
     9121 aaattctgcg ggcgcgttaa ctttgcctaa atgaatggca tccaaagcaa tcattttttc
     9181 ttcgttagtc ggaataacgg cacaaatgac acgcgcattt tcactggaaa caattcgctc
     9241 accacaggag ttagagcgat tattcatttc tgtatcaatc tctaagccta atacagccaa
     9301 atgttccatg accagacgac gaattaagct tgaattctct cctattccgc cggtgaatat
     9361 aattccatcc aggcgacgta atgaagctgc gtgtccggca atatgacggg caattcggtg
     9421 aacaaaggtt ttaattgcca gttgcgcgcg ttcgtgacct tcatgccagg ctttttccag
     9481 aacacgtaaa tccgaagaaa gaccggaaat acctaataat cccgactctt tattcactac
     9541 gcgttccagg tcacccaggc tctggttggt ttggctggcg acccaggaca tcgcaccaaa
     9601 gtcgacatcg ccactgcggg tacccatcat caagccttcc agcggcgtca ttcccattga
     9661 ggtatcaaca ctctgaccgt tgcgaaccgc gcagattgac gcgccattgc caagatgcgc
     9721 cacaaccagg ccggagtcat cttccgccag attcagcagc gaatgtgcgc gctgggaaac
     9781 atagcggtgc gacgtgccgt ggaaaccata acggcgtaca cctaactctt cataatattt
     9841 ccacggcagg ccgtataaat aagcttccgg agccatcgtc tggtggaaac tggtatcaaa
     9901 taccgccacc tgagttacgc ccggaaataa ttgctgcgcc gattcaatac cacttaaatt
     9961 ggcgtaatta tgcaggggtg ccagtggaga aacgcgacgg atattatcaa tgacttcatc
    10021 ggtaataatg gcggactcgg taaaaatact gccgccgtga gcgatgcggt ggccaattaa
    10081 ggccacactg tcatttaaat tccgtttttc cagttcaaat gcaattgcct tcaatgcacc
    10141 ttcgtagctg tggtgagcca gcggtgctgg ctctccccca tttacggata agaatgcatt
    10201 ttccgagtta ataccgtcgg caatacctga cattaatact tcacagtcgc tggcatcgag
    10261 cacggaaaac ttaatcgaag acgaaccaca gttaataacc aaaacaaccg gaaattcatt
    10321 catctctttt ctcatcctga gttacggatt aaaacagttt gtatacgatg ttcaggatgg
    10381 tcagcagacc aatcacggta acaaacacgt tatccagacg accacggtat ttcgccagag
    10441 acggcgcttt acggatggca tacatcggca acaggcacag cagggatgcg ataatcggtg
    10501 cgcccatggc ttcaatcagg tcaaggatgt tcgggttggc gtaggcaaca acccaggtgg
    10561 agcccatgat gaagatcatg ctgatagtgt tcagtttacc cagcgacact ttagttttgt
    10621 cgcctttata accaaacttc aggaccaggc cattcagacc ttccagcgtt cccagatagt
    10681 gaccgaagaa agatttgaag atagccacga gtgcgatgat ggaagccgca tattccagtg
    10741 taatcgcgaa cgttgttttg gtaccggtca tggacgcaaa gtggttagcc agataagaaa
    10801 gcactggaat attctgcgct ttggcttccg ccatgttggc cggagacaga gtaaacaggc
    10861 agctaaaggc aaagaacatc accactgcaa ccatcagcat gctggcacga gaaatgattt
    10921 gggaacattt acgttcggtg aagtcgcgac cgaagtcttt ctcatactct tcacgcttag
    10981 aaaccacgaa ggaagagacg attggcgaga agttaaagga gaaaaccatg atggaaatcc
    11041 ccagccagac agtgatcagg ataccgtcat gaccggttaa cgacagcgaa ccgaggtcaa
    11101 cctggtcgat aactgcagag ttccagtaag ggatcagcga caaagaaatc agcaccaggc
    11161 tggcgataaa cggccatacc aggtagctca tcactttaac catcagatcc ttaccaaacc
    11221 agatgacgaa agccatcagc agcaacagga acagcgccac aaagccgcga ttcagcggtg
    11281 caaagccgag ctggttttcc cagaacgtca taaaggtatt ggtaatagta acgccataaa
    11341 tccacagcag tgggcaaatc gcgaagaagt acaggaacgt gataaccacg ccgccagttt
    11401 taccaaaatg ctcttccacc gtttccgtaa tgttgccgga agggttagag ccagaaagac
    11461 acagacgcgc cagcgcccgg tggcaataaa acgcgatggg gtatgccaat accaacatca
    11521 gaagaatcgg gatcagtccg ccaaaacctg cgcggatagg gaagaacagc accccggcgc
    11581 cgattgccgt accaaacaag cctaacgtcc atgtggtatc tgatttacgc caggacgatt
    11641 gttttgtctg gctggataca atgctatctg aagtactcat atcctatcct caacgaatta
    11701 attaagcgtc aacgaaaccg gtgatttgag agacgcgaga aagatcgata ttgccgccgg
    11761 aaataatact gacggttttt ctgttttgaa tatattggtc taatttaccg cttaataatg
    11821 cagcacatgc cagagcgcct gcgccttcgg tgacgacttt attgcgctga attaaggcaa
    11881 tcatactgtt tctgatttcg tcttcgctga ccagcacgat gtcatcgact aattcacgaa
    11941 cgatttcgta agttaaatta cccgggcggg agacatcaca accatccgcc agggtgccgg
    12001 tagttcggtg cgtggttatt tctccggagt ggaaagaagc cgccatgccg tgaacgtttt
    12061 cagactgtac gccaataaca cgaatggtcg ggttaataga tttaattgcc accgcaatac
    12121 cagcaattaa accgccacca ccaattggca caatcacgtt atcgacatca tagagatctt
    12181 ccataatttc cagaccaatc gttccctggc cagcaatcac tttcggatca tcgtaaggtg
    12241 ggataaaaat acggccttcc atttcgacaa tttcgctcac tttagcgata gtgtcgttga
    12301 agttatcacc atgcagaacg acttctgcgg agtagtcgca cgttgccgct actttggatt
    12361 ttggcgcacc ttttggcatc accactttac cgtcgatacc cagcatcgcg caggagaggg
    12421 aaaccccttg cgcatggttg cccgcagaac aggccaccac gcctttgcgt ttttccgcat
    12481 cggtcagtga acttaattta ttaaatgcgc cacgaatttt aaatgaaccc gtacgctgca
    12541 tattttcaaa cttcaggaat atttcacctt tgcaacgttc actaaaatag ttggagcgag
    12601 gcatgcctgt tttataaatt cgcccagcca gtcgttgttt cgcttcaata atgtcatcaa
    12661 tagcaaccgg cagatcgtat gtaatatgca ttataaagcc tcttcgcctg aattaaatat
    12721 gtaggtaacc gtaaccgaca cctgcaagac agacaggtgg attatttatg tttaaataaa
    12781 aacaaataac taaccaactt c
//
LOCUS       DAPHKZ010000130        12760 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.130, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000130 DAPHKZ010000000
VERSION     DAPHKZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12760
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.130"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(161..1810)
                     /gene="actP"
                     /locus_tag="RH288_003776"
     CDS             complement(161..1810)
                     /gene="actP"
                     /locus_tag="RH288_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HDV4032789.1"
                     /translation="MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAG
                     HLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     KKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSITVAF
                     LGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH"
     gene            complement(1807..2121)
                     /locus_tag="RH288_003777"
     CDS             complement(1807..2121)
                     /locus_tag="RH288_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HDV4032790.1"
                     /translation="MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLI
                     AFAPGWLGTPLNPNTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQ
                     AS"
     gene            complement(2322..4280)
                     /gene="acs"
                     /locus_tag="RH288_003778"
     CDS             complement(2322..4280)
                     /gene="acs"
                     /locus_tag="RH288_003778"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HDV4032791.1"
                     /translation="MSQIHKHTIPANIADRCLINPQQYEAMYQQSINVPDTFWGEQGK
                     ILDWIKPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAVAGRIIDSNSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVV
                     VLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVD
                     NEGNPLEGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            4673..6109
                     /gene="nrfA"
                     /locus_tag="RH288_003779"
     CDS             4673..6109
                     /gene="nrfA"
                     /locus_tag="RH288_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HDV4032792.1"
                     /translation="MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNET
                     FAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVR
                     ETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
                     ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQ
                     SINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQ
                     IKAEKQDFIKTVIPQWEEQARKNGLLSQ"
     gene            6154..6720
                     /gene="nrfB"
                     /locus_tag="RH288_003780"
     CDS             6154..6720
                     /gene="nrfB"
                     /locus_tag="RH288_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HDV4032793.1"
                     /translation="MSVLRSLLTAGVLASGLLWSLNGITATPAAQASDDRYEVTQQRN
                     PDAACLDCHKPDTEGMHGKHASVINPNNKLPVTCTNCHGQPSPQHREGVKDVMRFNEP
                     MYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
                     KICVDCHSDQRTNPNFNPASVPLLKEQP"
     gene            6717..7388
                     /gene="nrfC"
                     /locus_tag="RH288_003781"
     CDS             6717..7388
                     /gene="nrfC"
                     /locus_tag="RH288_003781"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HDV4032794.1"
                     /translation="MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDES
                     LCIGCTACMDACREVNKVPEGVSRLTIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTNL
                     QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKY
                     GEVSQ"
     gene            7385..8341
                     /gene="nrfD"
                     /locus_tag="RH288_003782"
     CDS             7385..8341
                     /gene="nrfD"
                     /locus_tag="RH288_003782"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HDV4032795.1"
                     /translation="MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQ
                     AGGADSTLLRTTLIVGPGAVILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMAIRQRSNPHSTEAQFVH
                     RMEIPVVWGEIFLLVAFFVGLALGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPM
                     LLKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA"
     gene            8361..10079
                     /locus_tag="RH288_003783"
     CDS             8361..10079
                     /locus_tag="RH288_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HDV4032796.1"
                     /translation="MDVFLPEVGFLALLLSLGVNVLTPLTAFAGVRLRWPAMMRLTCI
                     GILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLW
                     VLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEG
                     RDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRSEFDGACARICWRWALPGW
                     SALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQRGIFRH
                     WSLLLAIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFSLFALISLASLALYGW
                     RARDGGPAVRFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPY
                     FNRATLPFGLLMLVVIVLATFVSGKRAQLPALVAHAGVLLFAAGVVVSSVSRQEISLN
                     LQPGQPVTLAGYTFRFERLDLQAKGNYTSEKAIVALFDHQQRIGELTPERRFYEARRQ
                     QMMEPSIRWNGIHDWYAVMGEKTGLDRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWR
                     GRKRDE"
     gene            10072..10455
                     /gene="nrfF"
                     /locus_tag="RH288_003784"
     CDS             10072..10455
                     /gene="nrfF"
                     /locus_tag="RH288_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HDV4032797.1"
                     /translation="MSKGLLTLLLLFTCFARAQVVDTWQFANPQQQEQALNIASQLRC
                     PQCQNQNLLESNAPVAVSMRHQVYSMVAEGKNEVEIIGWMTERYGDFVRYNPPLTGQT
                     LVLWALPVVLLLLMALILWRVRAKR"
     gene            10452..11048
                     /gene="nrfG"
                     /locus_tag="RH288_003785"
     CDS             10452..11048
                     /gene="nrfG"
                     /locus_tag="RH288_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HDV4032798.1"
                     /translation="MKQPKIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRQRD
                     PLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQL
                     HGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY
                     AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD"
     gene            11390..12703
                     /gene="gltP"
                     /locus_tag="RH288_003786"
     CDS             11390..12703
                     /gene="gltP"
                     /locus_tag="RH288_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HDV4032799.1"
                     /translation="MKSIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPA
                     GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIILGITL
                     ANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVT
                     VANFGFSSLWPLAKLVLLVHFAILFFALVVLGIVARLCGLSVWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ"
BASE COUNT         2849 a         3318 c         3560 g         3033 t
ORIGIN      
        1 aacaagaaag aaaaggcata ttctctgcat tatcattttc tacgactgtc aaaaatcgct
       61 cattttttaa tgagtttatt tgtttaatat tttgggaaaa ggtgatgcat gctggagagg
      121 aagagtattc cccggtcagg cgaccgggga aggggagaga ttaatgtgcg cggccttgct
      181 caacgccaaa gccggtctgg gagcggataa actgcgcgcg gaacagttca cgctcgcgcg
      241 ccccttccgc tgagttatcg gttgccgaga agaaccagat gccgaggaat gccacggtga
      301 tagagaacag cgccgggtat tcatacggga agatggcttt ttcgtgacca aggatctgta
      361 cccaaatcgt cgggccgagg atcatcagta ctactgcggt aatcagcccc agccagccac
      421 ccatcatcgc gccacgcgtg gtcagtttcg accagtacat agaaagcaga atgatcggga
      481 agttacagct cgccgcgatg gcaaacgcca gccccaccat aaaggcgatg ttctgattct
      541 caaacagcac gccgaggata atcgcaatca cgccgaggat cagtacggtg atttttgata
      601 cccgcagctc ttcacgttcg gtcgcgcctt ttttgaagac gttagcgtac aagtcatgcg
      661 aaaccgcgga tgcgcccgcc agcgtcagac ccgcaaccac cgcgaggata gtggcgaaag
      721 caaccgctga aataaaaccg aggaacaggt tgccgcccac tgcattcgcc aggtgaacgg
      781 ccgccatgtt gttaccacca atcagatggc ccgccgcgtc tttatattcc ggattcgcac
      841 caaccagcat gatcgcgccg aagccgataa taaaggtcag aatatagaag tagcccataa
      901 acccggtggc gtagaacacg ctcttacgtg cttcgcgggc atcgctgact gtaaagaagc
      961 gcatcagaat gtgcggcaag cccgccgtac caaacatcag tcccagaccc agagagagcg
     1021 cggagatcgg atctttcacc agcccgcccg gcttcatgat gtcgacccct ttcgggtgta
     1081 ccgccatcgc ttcgctgaac agattgttga agctaaagcc aacgtgtttc atcaccataa
     1141 aggccataaa gctggcaccg aacagtaaca gcacggcttt aataatttgc acccaggtgg
     1201 tcgccagcat gccgccgaac aggacataca tcatcatcag cacgccgacc agcaccaccg
     1261 caatgtgata gttaaggcca aacagcagct cgatcagttt acctgcgcct accatctgag
     1321 cgataaggta aagcgccacc accaccagag aaccacaggc cgaaagaata cgaatcggcc
     1381 cttgtttcag gcggtaagag gctacatcgg caaaggtgta gcgtcccagg ttacgcagac
     1441 gttcggcaat caggaacaaa atgatcggcc agcccaccag gaagcccagc gagtaaatta
     1501 agccgtcata gccggaggta aacaccagtg cggagatccc caaaaatgag gcggcggaca
     1561 tatagtcacc ggcaatcgcc agcccgttct ggaagcctgt gatattgccg cctgccgtgt
     1621 agtagtcgct acgagaacgt acgcgttttg atgcccagta agtaatgccg agcgtaaaca
     1681 cgacgaaaat caggaacata ataatcgcct gccagttcgt tggctggcgc tctacggccc
     1741 cgctaatagc atccgcggcg ttagctgcga aagggagtgt ggcggcaagc gccgtcagaa
     1801 ctcttttcat gatgcttgta cctcatgcag gacttcgtta ttaagacggt cgaattcgcc
     1861 gttcgcccgc cagatgtaga taccggtgag aacaaaggag atcacaatca ctccaacacc
     1921 aatcggaata ccgcgtgtga cgctggtgtt cggattcagc ggggtgccca gccagccggg
     1981 cgcgaaggcg atcagtaaaa taaagccgat ataaactgcc agcataataa tcgacaggat
     2041 ggtggcaaac cgttgccgtt tttcgactaa ctccctgaaa tgcgcattgt cttctatccg
     2101 ctgataaatc gtaccattca tcacagattc tccagaggta atgtagggat tgttttaatt
     2161 cccgctccct tatgggagaa ggttaacgct cgggtaaccc ttgccgaatg taggccggat
     2221 aaggcgttat acgccgcatc cggcaatcaa tgcctgatgc gacgctgtcg cgtcttatca
     2281 ggcctacaaa ccgttaccga ctcgcatccg gcaattgtgg gttacgatgg catcgcgata
     2341 gcctgcttct cttcaagcag cttctcgact acgccaggat cggcaagcgt cgaggtatcg
     2401 cccaggttgc tggtatcgcc cgccgcaatt ttgcgcagaa tacggcgcat aattttgccg
     2461 gagcgggttt taggcaggga gtcggtccag tgcagcacgt ctggcgtcgc cagcgggcca
     2521 atctctttac gcacccagtt gcggacttct gcgtacagtt ctggtgacgg ttcctccccg
     2581 tgattaagcg tgacgtaggc gtagatcgcc tgacctttaa tattgtgcgg aatacctact
     2641 acggcggctt cggcaatctt cggatgcgcc accagcgccg actcaatctc cgccgttccc
     2701 agacggtgac cggagacgtt cagcacatcg tccacacgcc cggttatcca gtaatagcca
     2761 tcttcatcgc gacgcgcgcc gtcgccgctg aaatacatat ttttgaaggt ggagaagtag
     2821 gtctgttcaa aacgttcgtg atcgccaaac agcgtacgcg cctgacccgg ccaggagtcg
     2881 gtgatcacca ggctgccttc ggtagcgcct tccagcgggt taccttcgtt atcgaccagc
     2941 gccggttgca cgccgaagaa cggacgtgtt gccgaaccgg ctttcagctc ggtagcgcca
     3001 ggcagcggcg tgatcatgaa accgccagtt tcggtctgcc accaggtatc gaccaccgga
     3061 catttctcgt tgccgatttt tttccagtac cactcccacg cttccgggtt gattggctcg
     3121 cccacggaac cgagaatgcg cagcgacgat cggtcggtgc cttcaatcgc tttatcccct
     3181 tccgccatca gcgcgcgaat cgccgtgggc gcggtataga gaatattgac ctgatgcttg
     3241 tccaccacct gcgccatacg ggcaggcgtc ggccagttcg gtacgccttc aaacatcagc
     3301 gtggtcgcac cgcaggccag cgggccgtac agcaagtaac tgtgtccggt cacccagccc
     3361 acatcggcgg tgcaccagta gatatcaccc ggatgataat caaagacata tttaaaggtc
     3421 agcgccgcgt acaccagata accgccggta gtatgcagca caccttttgg cttaccggta
     3481 gaaccggagg tgtagagaat aaacagcgga tcttcggcgt tcatctcttc cgcctggtgc
     3541 tgatcgctcg cttgctcaac caggtcgtgc caccacaggt cgcgcccttc ctgccagtca
     3601 attttcccgc cagtacgctt cagtaccacc acatgctcta cgctggtgac gttcgggttt
     3661 ttcagcgcgt catcaacgtt tttcttcagc ggaatactgc gcccggcacg cacaccttcg
     3721 tcggaagtga tcaccagtcg tgagttggaa tcaataatgc gcccggcaac ggcttccggc
     3781 gagaagccgc cgaaaatcac cgaatgcacc gcgccaatgc gggcgcaggc cagcatcgca
     3841 accgcggctt ccggcaccat cggcatataa atcgccacca catcaccttt tttaatgccc
     3901 agctcgagca gggtattggc gaagcggcag acgtcgcggt gcagctcttt atagctgata
     3961 tgtttgctct ggctggcgtc gtcgccttcc cagatgatgg cggtacgatc gccgttttct
     4021 tgcagatggc ggtcaaggca gtttgccgcc agattcagcg tgccgtcctc gtaccattta
     4081 atggacacat taccgggggc aaaggaggtg tttttcacct tctggtaagg tttgatccag
     4141 tcaagaattt ttccctgttc gccccagaag gtatcaggta cgttaataga ttgttgatac
     4201 atcgcctcgt actgctgagg gtttatcagg caacggtctg cgatgttggc aggaatggtg
     4261 tgtttgtgaa tttggctcat gcttttgttc tccttgtagg atgttaataa tatgtggcat
     4321 aagcgttaaa tgtaggggta ttggcagttt tgtttagtat ttgggcgaca gatcacgcaa
     4381 aagtagaatt gtgcaaataa acggcagggt aatttttgaa ggtcagcaac aaaagttgat
     4441 taattctttg aggaacatgc agttatgcat gctgttgaaa aagaggaaga tactgactaa
     4501 ctctaaagtg gtattttaca tgcacttaca attgattaaa gacaacattc acagtgtggt
     4561 tatttgttac acataggggc gagcaatgtc atgacagtgt aggtgcggtt actgtcgtga
     4621 aaaacaataa aaaccgccat tgcaacaatg gcgcaattcg gatgaagccc ctatgacaag
     4681 gataaaaata aacgcacgcc gtatcttcag cttattgatt ccttttttct ttttcacttc
     4741 tgttcacgct gaacaaacgg ctgctcccgc aaaacctgta actgtggaag cgaagaatga
     4801 aacctttgcc ccgcagcatc ccgatcaata tctctcctgg aaagccacct cggaacagtc
     4861 agagcgtgtt gacgccctgg cggaagatcc acggctggtg atcctgtggg cggggtatcc
     4921 cttctcgcgc gattacaaca agccgcgtgg acatgctttt gctgtgaccg atgtgcgtga
     4981 aaccctgcgt accggtgcgc cgaaaaacgc tgaagatggt ccgctaccga tggcatgctg
     5041 gagttgtaaa agcccggatg tggcgcgtct gatccagaaa gacggcgaag atggctactt
     5101 ccacggtaaa tgggcgcgcg gcggtccgga aatcgtcaac aacttaggtt gtgccgattg
     5161 ccataacacc gcctctccag agttcgccaa aggcaaaccg gagttaaccc tttcccgtcc
     5221 gtatgcggct cgcgcgatgg aagccattgg taaacctttt gagaaagccg gacgtttcga
     5281 ccagcaatcg atggtttgcg gtcagtgcca tgtggagtat tacttcgacg gcaaaaacaa
     5341 agcggttaaa ttcccgtggg atgacggcat gaaagtcgaa aatatggagc agtattacga
     5401 caaaattgcc ttctctgact ggactaactc cctgtcgaaa acgccaatgc tgaaagcgca
     5461 gcacccggaa tatgaaacct ggacagcggg cattcacggt aaaaacaacg tgacctgtat
     5521 cgactgccat atgccaaaag tgcagaacgc cgaaggcaaa ctctacaccg accataaaat
     5581 tggtaatccg tttgataact tcgcccagac ttgtgcgaac tgccataccc aggacaaagc
     5641 tgccttgcaa aaagtggtcg cggaacgtaa gcagtcgatt aacgacctga aaatcaaggt
     5701 tgaagatcaa ctggttcacg ctcacttcga agcgaaagca gcgctggatg caggcgcgac
     5761 ggaagctgaa atgaagccaa ttcaggacga tatccgtcat gcccagtggc gctgggatct
     5821 ggcgatcgct tcccacggca ttcatatgca cgcaccggaa gaaggtttac ggatgctcgg
     5881 tacggcgatg gataaagcgg cggatgcacg caccaaactg gcgcgcctgc tggcgaccaa
     5941 aggcatcacc catgaaatcc agatcccgga tatctcaacc aaagagaaag cccagcaggc
     6001 cattggcctg aacatggaac aaatcaaggc cgagaagcag gacttcatca aaacggtgat
     6061 cccgcagtgg gaagaacagg cacgtaaaaa cggtctgtta agccaataac cccgttccgc
     6121 ctcgcaaggg gcggaaaaca caatggagtg aatatgagcg tattacgttc gttattaact
     6181 gccggggtgc tggcgtcggg cctgttgtgg agcctgaacg gaattaccgc tacccctgcg
     6241 gcgcaggcat ctgatgatcg ctacgaagtt acccagcagc gtaacccgga tgccgcctgt
     6301 ctggactgtc ataaaccaga taccgaaggt atgcatggaa aacatgcttc cgttatcaac
     6361 ccgaataaca aactgccggt cacctgcacc aactgtcacg gccagccatc accgcaacac
     6421 cgcgaagggg tgaaagatgt gatgcgcttt aacgagccga tgtacaaggt tggagagcag
     6481 aacagcgtct gtatgtcctg tcatctgccg gaacagttgc aaaaagcgtt ctggccgcac
     6541 gatgtccacg taaccaaagt ggcgtgcgcc agctgccatt ccctgcatcc acagcaagat
     6601 acgatgcaga cgttaagtga caaaggacgg attaagattt gcgtcgattg ccacagcgat
     6661 cagcgcacca atccgaactt taacccggcg tctgttccgt tgcttaagga gcagccatga
     6721 cctggtctcg tcgccagttt ctcaccggcg tcggcgtgct ggcagccgtc agcggcaccg
     6781 cagggcgcgt ggtggcgaaa acgttgaata tcaatggggt gcgttacggc atggtgcatg
     6841 acgagtcgtt atgcatcggc tgtaccgcct gtatggatgc ttgtcgggaa gtgaacaagg
     6901 tgccggaagg cgtctcgcgc ctgacgatta ttcgtagcga gccgcagggc gaatttcctg
     6961 atgtgaaata tcgcttcttc cgtaagtctt gccagcactg cgatcatgcg ccgtgcgttg
     7021 acgtctgccc gaccggtgcg tcttttcgcg atgctgccag tgggattgtc gatgttaatc
     7081 cggatctctg cgtcggttgt cagtactgca tcgccgcctg tccgtaccgc gtgcgcttta
     7141 tccatccggt cacgaagacg gcggacaaat gcgatttctg ccgtaagacc aatttgcagg
     7201 ccggtaagtt gcccgcgtgc gttgaagctt gcccgaccaa ggcgctgacg tttggcaatc
     7261 tggacgatcc caacagtgag atttcgcaac tgctgcgcca gaagcccact taccgctaca
     7321 agctggcgct gggaaccaaa ccgaagctgt accgcgtacc gtttaaatac ggggaggtga
     7381 gccaatgacg cagacttccg catttcattt tgaatcgctg gtgtgggact ggccgattgc
     7441 catctacctg tttttgattg gtatttctgc tggtctggtg acgctggccg tgctgttacg
     7501 tcgcttctac ccgcaggcgg gcggtgcaga cagtacgttg ctgcgcacca cgctgattgt
     7561 cgggccgggc gcggtgatcc tcggtctgtt gatcctcgtc ttccacctga caagaccgtg
     7621 gaccttctgg aagctgatgt tccactacag ttttacctcg gtgatgtcga tgggggtgat
     7681 gctgtttcag ctctacatgg tggtgctggt gctgtggctg gcgaaaatct ttgaacatga
     7741 tttgcttgcc ctgcaacaac gctggttgcc gaagctgggg atcgtgcaaa aggttctgag
     7801 cctgctgacg cccgttcatc gcggactgga aacattgatg ctggtgctgg cggtgttgtt
     7861 gggggcttat accggctttc tgctgtcggc gctgaaatcg tatccgttcc tcaataaccc
     7921 gatcctgccg gtgctgttcc tcttctccgg catctcgtcc ggtgcggcgg tggcgctgat
     7981 cgccatggcg atacgccaac gcagtaaccc gcattccacg gaagcgcagt ttgtacaccg
     8041 tatggaaatc cctgtggtat ggggtgaaat cttcctgctg gtggcgtttt ttgtcggtct
     8101 ggcgctgggc gatgacggta aagttcgtgc gctggtggcg gcattaggtg gcggtttctg
     8161 gacgtggtgg ttctggcttg gtgtcgccgg gctggggctg attgtgccaa tgttgctcaa
     8221 accgtgggtc aatcgcagtt ccggcattcc tgccgtgctg gcggcgtgtg gggccagtct
     8281 ggtcggcgtg ttgatgctgc gctttttcat tctctacgcc ggacagttga cggtggcgta
     8341 agccagaaaa gaggtggttt ctggacgtat tccttcctga agtcggtttt ctggcgttgt
     8401 tgttaagtct cggggtcaac gtgttgaccc cgttgacggc ctttgcggga gtgcggttgc
     8461 gctggcctgc catgatgcga ctcacttgca tcggcattct ggcgcagttc gcgctcctgc
     8521 tgctcgcctt tggcgtactg acgtattgtt ttctcatcag cgatttctcg gtcatttatg
     8581 tcgcgcaaca tagctacagc ctgctgtcgt gggaactcaa gctggcagcg gtgtggggcg
     8641 gccatgaagg ttcgctgctg ctttgggtgc tgctgctttc cgcctggagc gcgctgtttg
     8701 cctggcatta tcggcagcaa accgatccgc tatttccgct gacgctagcc gttttatctc
     8761 tcatgctcgc cgcactgcta ctgtttgtgg tgctgtggtc cgatcccttc gtgcggatat
     8821 ttccaccagc aatcgaaggc cgcgatctca atccgatgct gcaacatccc ggtcttatct
     8881 ttcatccacc gctgctttat ctcgggtatg gcggtttgat ggtggcggcg agcgtggcgc
     8941 tggcgagttt actgcgcagc gagtttgatg gtgcctgcgc ccgaatttgc tggcgctggg
     9001 cactacctgg ctggagcgca ttaacggcgg ggatcattct cggttcctgg tgggcctatt
     9061 gcgaactggg ctggggcggc tggtggttct gggatccggt ggaaaacgcc tctttattac
     9121 cctggctttc tgccactgcg ctgctgcaca gtttatctct gacacgtcag cgggggattt
     9181 tccgccactg gtcgctgctg ctggcgatag ttactctgat gctgtcgctg ctgggcacct
     9241 taattgtccg ttctggcatt ctggtttcgg ttcatgcgtt cgcgctggat aacgtccgcg
     9301 ccgtgccgtt gttcagcctg tttgcactga ttagccttgc gtctctggct ctgtatggct
     9361 ggcgagcgcg ggacggtggc ccggcggtgc gtttttcggg gttatcgcgg gaaatgttaa
     9421 tcctcgctac gctgttgctg ttttgcgcag tgctactgat cgtgctggtg ggaacgcttt
     9481 atccgatgat ttacggcctg ctgggctggg gacgcctctc cgttggcgca ccttatttta
     9541 accgcgcgac gttaccgttt ggtctgttga tgctggtggt gattgtgctg gcgacgtttg
     9601 tctctggcaa acgcgcgcag cttccggcgc tggtagctca tgcgggcgtg ctgttatttg
     9661 ccgctggggt cgtggtttcc agcgtcagcc gtcaggaaat cagcctgaat ttacagccgg
     9721 gtcagccggt gacgctggca ggatacacct tccgttttga gcgcctcgat ctgcaagcca
     9781 aaggcaatta caccagcgaa aaagcgatag tggcgctgtt tgaccatcag caacgcattg
     9841 gtgaattaac gccggagcgg cgtttttacg aagctcgtcg tcagcaaatg atggaaccgt
     9901 caattcgctg gaacggcatc catgactggt atgcggtcat gggggagaaa actgggctgg
     9961 atcgttacgc ttttcgtttg tatgtacaaa gcggtgtgcg ctggatctgg gggggaggat
    10021 tgttgatgat tgcaggcgca ttattaagcg gatggcgggg gaggaagcgc gatgagtaaa
    10081 ggacttctca cgctactgct gttatttacc tgttttgcgc gcgctcaggt tgtagacacc
    10141 tggcaattcg ctaatccgca acaacaggaa caggcgttaa atattgccag ccagttacgt
    10201 tgtccgcagt gccagaatca aaacttactg gaatccaatg cgccggtggc agtcagtatg
    10261 cgccatcagg tttacagcat ggtggcggag gggaagaacg aagtcgaaat cattggctgg
    10321 atgaccgaac gctacggaga ttttgttcgc tataacccac cgttaacggg tcagacgctg
    10381 gtgttatggg cgctgccagt ggtgttgtta ctactgatgg cactgatcct ctggcgagtg
    10441 agggcgaagc gatgaaacag cccaaaatac cggtgaaaat gctgacaaca ctcacaatat
    10501 tgatggtatt tctctgtgtc ggcagttatc tgttaagccc aaaatggcag gcggtacgtg
    10561 cggagtatca gcgtcagcgc gatccgctac atcagtttgc cagccagcaa accccggaag
    10621 cgcagcttca ggcattacag gataaaatcc gcgctaatcc acaaaacagc gaacagtggg
    10681 cgttactggg cgagtactat ctgtggcaaa acgattacag caattcgctg ctggcgtatc
    10741 gtcaggcgtt gcaactacat ggtgagaacg ctgaactgta tgcggcgctg gcgacggtgc
    10801 tttattacca ggccagccag catatgaccg cccagactcg cgcaatgatc gacaaagccc
    10861 tcgcgctgga ctctaacgaa atcaccgctc tgatgctgct ggcttccgat gcgtttatgc
    10921 aggcgaatta cgcgcaagcc atcgaactat ggcaaaaagt gatggatctc aactcacccc
    10981 ggatcaaccg gacacagctg gtcgagtcga ttaatatggc gaaactgttg cagcggagat
    11041 cggattaatc atctggtgat gaagattatg tcattgagct gcataaaaaa taatcgaatg
    11101 aacatatgcc aaaaataatc actaatcagt attattgcag attaaacaaa taaaaatctt
    11161 tccataacaa atggttattc attaatcctg ccataaactc gcgttattat gcattaatgc
    11221 agcgaaaagc tctgttgtta aagggttgcg caacataccg cgcaaatgat actgatcata
    11281 agcgttaaaa aaatctacaa accaacgcaa cacaattcat gccctggcag tatgtcacgt
    11341 tctcgcgttt ctgaacgggg aacggcgctc cattgaggaa gttattctga tgaaaagtat
    11401 aaaattcagc ctggcctggc agattctgtt tgctatggtg ctgggcattc tcctgggaag
    11461 ctacctgcac taccatagcg acagccgcga ctggctggtc gtcaatttgc tctctccggc
    11521 gggtgatatc ttcatccatc tgatcaaaat gattgttgtg ccgattgtga tctccacgct
    11581 ggtggtgggt atcgcgggtg ttggtgatgc caaacagctc gggcgtattg gcgcgaaaac
    11641 cattatttac ttcgaggtga tcaccaccgt cgccatcatt ttggggatca ctctggcgaa
    11701 cgtcttccag cccggtgccg gggtggatat gtcgcagctg gcgaccgtcg atatctcgaa
    11761 atatcagagc actacggaag cggtacaaag cagttcccac ggcattatgg gcacgatttt
    11821 gtcgctggtg ccgacgaaca ttgtggcgtc gatggcgaaa ggcgaaatgc tgccgatcat
    11881 cttcttctcg gtgctgtttg gtctggggct ttcctccctg cccgcgacgc atcgtgaacc
    11941 gctggtgacc gtgttccgct ccatctctga aaccatgttt aaagtgactc acatggtgat
    12001 gcgttatgca ccggtgggtg tgtttgcgct gattgcggtg acggtggcta actttggttt
    12061 ctcttctctg tggccactgg cgaaactggt gctgctggtg catttcgcca ttctgttctt
    12121 cgcgctggta gtgctgggaa ttgtggcgcg cctgtgcggg ttaagcgtct ggatcctgat
    12181 tcgtattctg aaagatgagc tgattctggc gtactccact gccagctctg aaagcgtact
    12241 gccgcgaatt attgagaaga tggaagccta cggagcaccg gcgtcgatca ccagcttcgt
    12301 ggtgccgacc ggttactctt ttaaccttga tggttcgacg ctgtatcaaa gtattgccgc
    12361 tattttcatc gctcagctgt atggcattga cctgtccatc tggcaggaaa tcattctggt
    12421 gctgacgctg atggtgacct cgaaagggat tgctggcgtg ccgggagtgt cgtttgtggt
    12481 gttgctggca acgctgggta gcgtaggtat tccgctggaa ggtctggcgt ttattgccgg
    12541 tgttgaccgt atcctcgaca tggcgcgtac tgcgctgaac gttgtgggta atgcgctggc
    12601 ggtgctggtg attgccaagt gggaacacaa atttgaccgc aaaaaggcgc tggcttatga
    12661 gcgtgaagtg ctgggtaaat ttgataaaac tgcggatcaa taattgaaga ttgccgggga
    12721 tatccacccg gcaatgtgtg gatgcctgat gcgacgctgg
//
LOCUS       DAPHKZ010000131        12708 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.131, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000131 DAPHKZ010000000
VERSION     DAPHKZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12708
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.131"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            218..667
                     /gene="rpiB"
                     /locus_tag="RH288_003787"
     CDS             218..667
                     /gene="rpiB"
                     /locus_tag="RH288_003787"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional allose-6-phosphate
                     isomerase/ribose-5-phosphate isomerase RpiB"
                     /protein_id="HDV4032800.1"
                     /translation="MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYP
                     HYASQVALAVAGGEVDGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDT
                     NVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQRRN"
     gene            736..1065
                     /gene="yjdP"
                     /locus_tag="RH288_003788"
     CDS             736..1065
                     /gene="yjdP"
                     /locus_tag="RH288_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YjdP"
                     /protein_id="HDV4032801.1"
                     /translation="MKRFPLFLLFTLLTLSTVPAQADIIDDTIGNIQQAINDAYNPDR
                     GRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDDRQRQLDQERRQLEDEERR
                     MEDEYGR"
     gene            complement(1212..1970)
                     /gene="phnP"
                     /locus_tag="RH288_003789"
     CDS             complement(1212..1970)
                     /gene="phnP"
                     /locus_tag="RH288_003789"
                     /EC_number="3.1.4.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnP"
                     /protein_id="HDV4032802.1"
                     /translation="MSLTLTLTGTGGAQGVPAWGCECAACARARRSPQYRRQPCSGVV
                     KFNDAITLIDAGLHDLADRWSPGSFQQFLLTHYHMDHVQGLFPLRWGVGDPIPVYGPP
                     DEQGCDDLFKHPGLLDFSHTVEPFVVFDLQGLQVTPLPLNHSKLTFGYLLETAHSRVA
                     WLSDTAGLPEKTLKFLRNNQPQVMVMDCSHPPRADAPRNHCDLNTVLALNQVIRSPRV
                     ILTHISHQFDAWLMENALPSGFEVGFDGMEIGVA"
     gene            complement(1972..2406)
                     /gene="phnO"
                     /locus_tag="RH288_003790"
     CDS             complement(1972..2406)
                     /gene="phnO"
                     /locus_tag="RH288_003790"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HDV4032803.1"
                     /translation="MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRD
                     PNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAE
                     EEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL"
     gene            complement(2393..2950)
                     /gene="phnN"
                     /locus_tag="RH288_003791"
     CDS             complement(2393..2950)
                     /gene="phnN"
                     /locus_tag="RH288_003791"
                     /EC_number="2.7.4.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphokinase"
                     /protein_id="HDV4032804.1"
                     /translation="MMGKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASA
                     GSENHIALSEQEFFTRAGQNLLALSWHANGLYYGVGVEIDLWLHAGFDVLVNGSRAHL
                     PQARARYQSALLPVCLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCHTLNN
                     DGSLRQSVDTLLTLIHQKEKHHACL"
     gene            complement(2950..4086)
                     /gene="phnM"
                     /locus_tag="RH288_003792"
     CDS             complement(2950..4086)
                     /gene="phnM"
                     /locus_tag="RH288_003792"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDV4032805.1"
                     /translation="MIINNVKLVLENEVVSGSLEVQNGEIRAFAESQSRLPEAMDGEG
                     GWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVR
                     DGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVQREPVTLV
                     SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRESIAAL
                     CRARKIALASHDDATHAHVAESHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVR
                     GGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDQSNRFTLPQAVKLVTKN
                     PAQALNLQDRGVIGEGKRADLVLAHRKDNHIHIDHVWRQGKRVF"
     gene            complement(4083..4763)
                     /gene="phnL"
                     /locus_tag="RH288_003793"
     CDS             complement(4083..4763)
                     /gene="phnL"
                     /locus_tag="RH288_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HDV4032806.1"
                     /translation="MINVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSG
                     SGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVI
                     PRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNI
                     ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKTRGAAIVGIFHDEAVRNDVADR
                     LHPMGASS"
     gene            complement(4874..5632)
                     /gene="phnK"
                     /locus_tag="RH288_003794"
     CDS             complement(4874..5632)
                     /gene="phnK"
                     /locus_tag="RH288_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="HDV4032807.1"
                     /translation="MNQPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGK
                     TTLLKSISARLTPQQGEIHYENRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSA
                     GGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
                     VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLV
                     MKQGQVVESGLTDRVLDDPHHPYTQLLVSSVLQN"
     gene            complement(5629..6474)
                     /gene="phnJ"
                     /locus_tag="RH288_003795"
     CDS             complement(5629..6474)
                     /gene="phnJ"
                     /locus_tag="RH288_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDV4032808.1"
                     /translation="MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPM
                     PYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAVSIRNFFKRVTGVNTTERTDDAT
                     VIQTRHRIPETPLTEDQIIIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
                     IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPP
                     FTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQS
                     EAKNQ"
     gene            complement(6467..7531)
                     /gene="phnI"
                     /locus_tag="RH288_003796"
     CDS             complement(6467..7531)
                     /gene="phnI"
                     /locus_tag="RH288_003796"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate synthase subunit PhnI"
                     /protein_id="HDV4032809.1"
                     /translation="MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLA
                     VDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTGMRLE
                     RRISAVYKDIPGGQLLGPTYDYTHRLLDFTLLANGEAPTLTTADSEQQPSPHVFSLLA
                     RQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRN
                     HPFAGEIRSGYIDVSIVPEELGFAVNVGELLMTECEMVNGFIDPPGEPPHFTRGYGLV
                     FGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHY
                     VDFQAELELLKRLQQEQNHG"
     gene            complement(7531..8115)
                     /gene="phnH"
                     /locus_tag="RH288_003797"
     CDS             complement(7531..8115)
                     /gene="phnH"
                     /locus_tag="RH288_003797"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDV4032810.1"
                     /translation="MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPL
                     NIATTSVLLTLADNDTPVWLSTPLNNDIVNQSLRFHTNAPLVSQPEQATFAVTDEAIS
                     SEQLNALSTGTAVAPEAGATLILQVASLSGGRMLRLTGAGIAEERMIAPQLPECILHE
                     LTERPHPFPLGIDLILTCGERLLAIPRTTHVEVC"
     gene            complement(8112..8564)
                     /gene="phnG"
                     /locus_tag="RH288_003798"
     CDS             complement(8112..8564)
                     /gene="phnG"
                     /locus_tag="RH288_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDV4032811.1"
                     /translation="MHADTATRQHWMSVLAHSQPAELAARLNALNITADYEVIRAAET
                     GLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVQGRDKQHAERCALIDALM
                     QQSRHFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA"
     gene            complement(8565..9290)
                     /gene="phnF"
                     /locus_tag="RH288_003799"
     CDS             complement(8565..9290)
                     /gene="phnF"
                     /locus_tag="RH288_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism transcriptional regulator
                     PhnF"
                     /protein_id="HDV4032812.1"
                     /translation="MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAAR
                     FEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPFDYPLNAQARFSQNLLDQGSHPT
                     SEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQ
                     RFDSGSLHDFLREQTGIALRRSQTRISARRAQAKECQRLEIPNMSPLLCVRTLNHRDG
                     ESSPAEYSVSLTRADMIEFTMEH"
     gene            complement(9311..10098)
                     /gene="phnE"
                     /locus_tag="RH288_003800"
                     /pseudo
     CDS             complement(9311..10098)
                     /gene="phnE"
                     /locus_tag="RH288_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313113.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
     gene            complement(10204..11220)
                     /gene="phnD"
                     /locus_tag="RH288_003801"
     CDS             complement(10204..11220)
                     /gene="phnD"
                     /locus_tag="RH288_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV4032813.1"
                     /translation="MNAKIIASLAFTSMFSLSTLLSPAHAEEQEKALNFGIISTESQQ
                     NLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGMRFNKVDIAWYGNLSAMEAVDRA
                     NGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
                     GYYVFAKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKE
                     LKVIWKSPLIPGDPIVWRKNLSETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASS
                     DLQLVPIRQLALFKEMQGVKSNKGLNEQDKLAKTTEIQAQLDDLDRLNNALSAMSSVS
                     KAVQ"
     gene            complement(11245..12033)
                     /gene="phnC"
                     /locus_tag="RH288_003802"
     CDS             complement(11245..12033)
                     /gene="phnC"
                     /locus_tag="RH288_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HDV4032814.1"
                     /translation="MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKS
                     TLLRHLSGLITGDKSVGSHIELLGRTVQREGRLARDIRKSRAHTGYIFQQFNLVNRLS
                     VLENVLIGALGSTPFWRTCFSWFTGEQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR
                     VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDTNQNDGITVVVTLHQVDYALR
                     YCERIVALRQGHVFYDGSSQQFDNERFDHLYRSINRVEENAKAA"
     gene            complement(12166..12609)
                     /gene="yjdN"
                     /locus_tag="RH288_003803"
     CDS             complement(12166..12609)
                     /gene="yjdN"
                     /locus_tag="RH288_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HDV4032815.1"
                     /translation="MPLSPYLSFAGNCSDAIAYYQRTLGAELLYKISFGEMPKSAQDS
                     AENCPSGMQFPDTAIAHANVRIAGSDIMMSDAMPSGKASYSGFTLVLDSQQVEEGKRW
                     FDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVVKQQPTQ"
BASE COUNT         2498 a         3578 c         3883 g         2749 t
ORIGIN      
        1 catttaatta gtttaaaaac atgatgttat ttgtttttct ggttttttag atgatagatg
       61 ttgctggatg gtgagtgtct ttaacgctat tgcgctgtca gatgtaactc tgtaaaacag
      121 atcaggaagg cgtaattcat cgattttggg tgtttttaat tcattaacat cacaaatgtt
      181 ttttgattgt gaagttttgc acggacgggg aagatgaatg aaaaagattg catttggctg
      241 tgatcatgtc ggtttcattt taaaacatga aatagtggca catttagttg agcgtggcgt
      301 tgaagtgatt gataaaggaa cctggtcgtc agagcgtact gattatccac attacgccag
      361 tcaagtcgca ctggctgttg ctggcggaga ggttgatggc gggattttga tttgtggtac
      421 tggcgtcggt atttcgatag cggcgaacaa gtttgccgga attcgcgcgg tcgtctgtag
      481 cgaaccttat tccgcgcaac tttcgcggca gcataacgac accaacgtgc tggcttttgg
      541 ttcacgagtg gttggcctcg aactggcaaa aatgattgtg gatgcgtggc tgggcgcaca
      601 gtacgaaggc ggtcgtcatc aacaacgcgt ggaggcgatt acggcaatag agcagcggag
      661 aaattgagat tcatccacta cttgcatgga tgagtaatga ttaatgtgga tagagtttct
      721 ttttgaggtt ggctaatgaa acgctttccg ctatttcttt tattcaccct gctcacgctg
      781 tccaccgttc cggcccaggc cgatattatc gacgacacca ttggcaatat tcagcaggcg
      841 attaatgacg cttataaccc tgaccgtggg cgagactatg aagattcgcg cgacgacggc
      901 tggcagcgtg aagtgagcga cgatcggcgc agacaatatg acgaccgccg ccgccagttt
      961 gaagatcgcc gcaggcagct ggacgatcgc cagcgccagc ttgatcagga gcgtcggcaa
     1021 ctggaggatg aagagcggag aatggaagat gagtatgggc gatgaggttg ggtatggagc
     1081 aggcatcgcc cctcacccca atggggagag ggagaaaacg agcgcaatat tcaatatcga
     1141 gcacaatcgg tcccctcgcc cctctgggga gagggttagg gtgagggggc cagcgcgcac
     1201 attccctctc atcacgccac cccaatctcc atcccatcaa accccacctc aaaccctgac
     1261 ggtagtgcgt tttccatcag ccacgcatca aactggtggc tgatatgggt cagaatcacc
     1321 cgtggcgagc ggataacctg attcagcgca agcacggtat ttaaatcaca gtgattacgc
     1381 ggtgcatccg cgcgcggcgg gtgactgcaa tccatcacca ttacctgcgg ctgattattg
     1441 cgtaaaaatt tcagcgtttt ttccggcaag cctgcggtgt cagacagcca cgccacccgg
     1501 ctgtgtgccg tttccagcag ataaccgaag gtcagttttg agtggttgag cggcaggggc
     1561 gtgacctgta acccctgcaa atcaaacacc acaaacggtt ccaccgtgtg gctgaaatca
     1621 agcaggcccg gatgtttaaa cagatcgtcg cagccctgtt catccggcgg gccgtaaacc
     1681 gggatcggat cgccaacgcc ccagcgcagc ggaaacagcc cctggacgtg atccatatga
     1741 taatgcgtca gcaaaaactg ctggaacgat ccgggcgacc agcgatcggc gagatcgtgc
     1801 agcccggcgt cgatcagggt gattgcgtcg ttaaacttca ctacgccgct gcacggttgg
     1861 cggcgatact gcggcgagcg ccgcgctctg gcgcaggccg cacactcgca gccccatgcc
     1921 ggaacgccct gtgcgccgcc ggtgccggtg agcgtgaggg tcaggctcat gttacagcgc
     1981 cttggtgaag cggaagtggc tctgctcgta gccttcgcgc agatagaaac ggtgcgcgtc
     2041 gtggcgcttc acgttggtcg aaagttcggt catttcggcc ccggcctggc gggcttcttc
     2101 ttctgcccac gccagtaact tactgccgac gttcagaccg cgcgcctgcg gcattaccac
     2161 caactcctga atttcgccga tccagttgac atgatgcaga tgaaactgca aatgcaggcc
     2221 gatcatgccg acaacttcgc catcaagcag cgccagatgg tagcgcatgt ttgggtcgcg
     2281 cagattggcg ttaaaaccca cgcgaaacgc gtggtggtca aactccgcct gttttagctc
     2341 acaaatcagc gcgtaaaccg cgtcggtgtc gtactgcgtg gccgggcgaa gctcacaagc
     2401 aggcatggtg tttctccttc tgatggatca gcgtcagcag cgtgtcgacc gactggcgca
     2461 ggctgccgtc attgttgagc gtatggcaat cctgtggagt atagcgggcg gcgcgcgcca
     2521 ggcgggcgtt aatttcactg gcgttttcac ggccacggtt ttccaggcgc tggcggagga
     2581 tctccggcga aacctgtaaa cagacgggca gcagcgccga ttgatagcgc gcccgcgcct
     2641 gcggcagatg ggcgcgtgag ccgttgacca gcacgtcgaa tccggcgtgc agccagagat
     2701 caatctcgac gccgacgcca taatacagac cgttagcgtg ccagcttaag gccaacagat
     2761 tttgccccgc gcgggtaaaa aactcctgct cgctcagggc gatatggttt tcacttccgg
     2821 cgctggcatc gcgcgtgatg tagcgatgcg ccaccagtaa ctgagtttgt tcccgcaggc
     2881 ggagttccgc cagcaggctg tctttcccgg agccggacgg ccccattaac caaatcagtt
     2941 ttcccatcat cagaacaccc ttttaccctg acgccagacg tggtcgatat gaatatgatt
     3001 gtccttgcga tgcgccagca ccaggtcggc gcgtttgccc tcgccaatca ccccgcgatc
     3061 ctggagatta agcgcctgcg ctggattttt agtcaccagc ttcaccgcct gcggcagcgt
     3121 aaagcggttg ctctggtcat cggcgacgcg aaatgccgca tcgagcaggc tggcggggta
     3181 gtagtcggaa gagaggatat ccagcaggcc aagctgcgcc agttcactgg ccgccacgtt
     3241 gccggagtgc gagccgccgc gcacaatatt cggcgcgccc atcagcacgt tcatgccatg
     3301 cttgcgcgag gcttccgccg cttcgaacgt ggtgggaaat tcggcgatca cgctgccaag
     3361 ctggtgagat tcagcaacgt gggcgtgggt ggcgtcatcg tggctggcaa gcgcaatttt
     3421 tcgcgcgcgg cacagggcgg cgatggattc gcgattcggc tgcgaccagc gtgcggcgag
     3481 cgccagttgc tcttcttcgt actgctgcat ctgcgcatca gtgagggagt atttgccctg
     3541 ataatattcg cgatacttct cgcggttggc gaactggcgc tggcccggcg agtggtccat
     3601 cagcgacacc agcgtcaccg gctcgcgctg caccagtttt tcaaacagcg gcagcgtggt
     3661 gtgatgcggc agttcgcagc gcagatgcag acggtgctcg gcgcggttga cgccgcgttt
     3721 ctgcgtctct tcgatggcgt tgatcatctt ctccagattc tccagccgat cgccgccgtc
     3781 gcgcacgtcg ccaattgcca cggcatccag tacggtggtg atgccgctcg ccaccatcag
     3841 cgcgtcgtgg ctgctcatcg ccgagtgggc aggccagtca actttcgggc gcggggtgaa
     3901 gaatttatcc agattatcgg tatgcagctc aatcagcccc ggcagcagcc agccgccttc
     3961 gccgtccatc gcctccggca ggcggctctg gctttcggca aaggcgcgga tttcgccgtt
     4021 ctgcacctcc agcgaaccgc ttaccacctc gttttccagc accagcttaa cgttattgat
     4081 aatcatgaag aggctcccat tgggtgcagg cggtcggcga cgtcattacg tacagcttcg
     4141 tcatggaaga tgcctacgat ggctgcgcca cgggttttgg cttcgcgaat cagttccacc
     4201 accgcggcgc tgtttttggc gtccagcgag gcggtaggtt cgtcaagcag cagaatgggg
     4261 tagtcgacga taaagccgcg ggcgatgttg acgcgctgct gttcgccacc ggaaaatgtc
     4321 gatggtgcca ggtgccacag gcgttccggc acgttcaggc gggtgagaag acgcgcggct
     4381 ttagcggcgc aggcttcacg cggaacgccg gtatcgagca gcggctgcat caccacttcc
     4441 agtgctgaga tacgcgggat gacgcgcaga aactggctca cccagccgac ggtggttttg
     4501 cggatttcca ccactttgcg cgctggcgcg gtgaccaggt ctacccactc gtcaccgtgt
     4561 ttgatctgga tttgaccttc gtcgggcaga tagttggcgt acagcgagcg tagcagagtt
     4621 gatttgccgc tgccggaatg gccgtggagc accacgcatt cgcccgcgtt gacggtgagc
     4681 gaggcgcgat tgaggacggg caggcgcacg ccgttttgct ggtgcaggat gaaggtttta
     4741 ctgacgtttt gtacgttaat catttttcgc ctcgtggttc gggtgtcgga tgcgacgctg
     4801 acgcgtctta tccgacctac ggggagcgca tttgtaggcc ggataaggcg tttacgccgc
     4861 atccggcacc ggctcaattc tgcaaaaccg atgacaccag cagctgtgta tacggatgat
     4921 gcgggtcgtc gagcacgcgg tcggttaacc cactctccac cacttgcccc tgcttcatca
     4981 ccagcaaacg gtccgccagc aggcgggcga cgcctaaatc atgggtgaca atcaccaccg
     5041 cgaggttcag ctccaccacc aggccgcgca gcaggtcgag caggcgggcc tgcaccgaca
     5101 catccagccc gccggtcggt tcatccataa acaccagctt cggatgcgtc accaggttgc
     5161 gggcaatctg caaacgctgc tgcataccgc cggaaaaggt ggtcggcagg tcgtcgatcc
     5221 ggttggcggg aatctccacc tcttccagcc acttctgcgc ggtggcacga atatcgccgt
     5281 aatgacgtgc cccggtcgcc atcagccgct cgccgatatt gccgcctgcc gacacctggc
     5341 ggcgcaggcc gtcgagtgga tgctgatgca ccacgcccca ttcggtacgc agcaggcgac
     5401 ggcggtcggc ctcgctcatt gcatacagcg aacggttctc gtagtgaatt tccccctgct
     5461 gcggcgtcag gcgcgcggag atcgacttca gcagcgtggt cttcccggag ccggattccc
     5521 cgacaatgcc cagcacttcc cccggccata aatcaaaaga gacatcgcta aagcctttgc
     5581 ccggcgcgta aaggtgggtc aggttattga ccgaaagtaa cggttgattc attggttttt
     5641 tgcctcgctc tgttggcggc aataatcggt atcggagcag acaaacatgc ggtttccggc
     5701 gtcatccagc accacttcat caagatagct gtgggtcgat ccgcagatgg cgcatggctc
     5761 atcccactgc tgaacggtga acgggtgatc gtcgaaatcg agactttcca cgcgggtaaa
     5821 cggcggcacc gcatagatgc gcttctcgcg ccccgcgccg aacagttgca gggcgggcat
     5881 catgtccatt tttgggttat cgaatttcgg gatcggcgac gggtccatca cgtagcgccc
     5941 atttaccttc accggatagg cgtaggtggt ggcgatatga ccgaagcggg cgatatcttc
     6001 atacagtttc acctgcatca cgccgtactc ttccagcgcg tgcatggtgc gggtttccgt
     6061 ttcgcgcggc tcgataaagc gcagcggctc ggggattggc acctggaaga taattatctg
     6121 atcttcggtc agcggcgttt cggggatgcg gtgacgcgtc tggataaccg tcgcatcgtc
     6181 cgtacgttcc gtggtgttta ccccggtcac gcgcttgaag aagttgcgaa tcgacacggc
     6241 gttggtggtg tcatccgcgc cctggtcaat caccttcagc acgtcgcttt cgccaatcac
     6301 gctggcggta agctgaatgc cgccggttcc ccagccgtac ggcatcggca tctcgcgccc
     6361 gccaaacggc acctgataac cggggatcgc caccgctttt aagatggcgc ggcggatcat
     6421 gcgtttggtc tgctcgtcga ggtaggcaaa gttgtagccg ctcagattag ccatggttct
     6481 gctcctgttg cagacgtttg agtagctcca gttcggcctg gaaatcgacg tagtggggga
     6541 gtttgaggtg tgagacaaag cctgcggctt cgacgttgtc ggcatgtgcc agcacgaact
     6601 cttcatcctg cgccgggcct gtcgcgtgct cgccgtactc cggggcttgc agagcgcggt
     6661 cgaccagcgc catcgccatc gctttgcgct cgctcatgcc gaacaccagc ccgtagccgc
     6721 gcgtgaagtg cggcggctca cccggcgggt cgataaaacc gttaaccatt tcacactcag
     6781 tcatcagcag ttcgccgacg ttcaccgcaa atcccagctc ttccggcaca atcgacacgt
     6841 cgatatagcc gctgcggatc tcgcctgcga acgggtgatt gcgcccgtaa ccgcgttggg
     6901 tggagtaggc cagcgccagc aaatagcctt cgtcgccgcg catcaactgc tgcaaacggg
     6961 aggagcgtga gcaggggtaa accggcggcg tgcgggtgat gtcatccggc tgtgcgccgc
     7021 tatcctcttc aaacttcgcc agcccctgac gcgccagcag gctgaaaacg tgcggcgacg
     7081 gctgctgttc gctgtcggcg gtggtcagcg tcggcgcttc gccgtttgcc agcagggtaa
     7141 aatcgagcag gcgatgggtg tagtcgtagg ttgggccaag cagctggccg ccgggaatgt
     7201 ctttataaac ggcggagata cggcgttcga gacgcatccc ggtggtgtcg agcggctcgc
     7261 ttaccgccag cttcgccaac gtggtgcggt aggcgcgcag caggaaaatc gcttcaacgt
     7321 tatcgccgct ggcctgtttc agcgccagcg ccgccagttc gcggtcggca atgccgcctt
     7381 cggtcatcac gcgatctacc gcgaggttaa gctgctgttc aatctgggcg acgctcagtt
     7441 cgggcaaatc ggtatcgcct cggcgtcggc tctcttgcag ggcgtgggcg gcgtcgatcg
     7501 ccttctcgcc ccctttcacg gcaacgtaca tcagcacacc tccacatgag tggttcgcgg
     7561 aatagccagc aggcgctcgc cacaggtcag gatcaggtcg atgccgagcg ggaacggatg
     7621 cgggcgctcg gtgagttcgt gcagaatgca ctccggcagc tgcggagcga tcattcgttc
     7681 ttcggcaata cccgcaccag taaggcgcaa catgcgtccg ccgctcaggc tggcgacctg
     7741 taaaatcagc gtcgcacccg cttccggcgc aacggcggtg ccggtggaaa gggcgttgag
     7801 ctgttcgctg gaaatcgcct catccgtcac cgcgaaggtc gcctgttccg gctggctgac
     7861 cagcggcgcg ttggtatgaa aacgcaggct ctggttgacg atatcgttat ttaatggggt
     7921 agaaagccac accggcgtgt cgttatcggc cagcgtcagc agcacgctgg tggtggcgat
     7981 attcagcggt tgccagccgc gtttgagctg atgcagggcg acaatcacgc ccggctcgct
     8041 catggccttt aacaggcgac gaaaactgtg ctgggcatcc tgcacgggaa gcataaaagc
     8101 ggtttccagg gtcatgcgtt gtctccgcga accatcgtaa agaagtcgac ccggctggcg
     8161 ttcacttcgg cctggcgtgc ggcaatgcgt gccatacggt cagcgtccag cggggcaata
     8221 agggtttctg ataagttttg aaagtggcga gattgctgca tcagcgcgtc aatcagcgcg
     8281 cagcgttcgg cgtgctgttt atcacgcccc tgcacccagc tgtagccgag cgtgccgtca
     8341 gtcaggcgca cggcggcgcg ggtcagcgtg gcgtcgccgg caaaaaaacg ttcgccggtg
     8401 ccgcccatcc gcgcctgaat ctgtaccagg ccagtttcag cggcgcggat cacctcatag
     8461 tcggcggtga tgtttagcgc gttcaggcgt gctgccagtt cagccggttg gctgtgcgcc
     8521 agcacggaca tccagtgctg gcgggtcgcg gtatctgcgt gcattcagtg ctccatagtg
     8581 aattcaatca tgtcggcgcg cgtcaggctg acggagtact ccgccgggct gctttcaccg
     8641 tcacggtggt taagggtgcg cacgcacagc agcggcgaca tattcgggat ttcaagacgc
     8701 tggcactctt tggcctgggc gcggcgggcg ctgatccgcg tctggctgcg gcgcagcgca
     8761 attccggttt gctcgcgcag aaaatcgtgc agcgagccgc tgtcgaagcg ttgcagcgtc
     8821 ggccagaggg tgaggtccgc gaagtagtgg tcgattaaac agagcgcgac gccgttgaca
     8881 cgacgcaggg tgcgcaggtg gatgacgttc tccccctcgg taatccccag tgcgtcagcg
     8941 acgtggccgg acgcggggcg caataccgaa agcagttttt cgctggtggg atggctgccc
     9001 tgatccagca gattctggct aaaacgcgcc tgggcgttga gcgggtaatc gaacgggcgc
     9061 atcagcacca gcacgccgac gccctgacgg cgctgtaccc agcctttttc caccagttgg
     9121 tcgatggcgc ggcgcagggt gtggcgattc acctcaaagc gcgctgccag ttgctgctcg
     9181 gcgggaagat agtcgccgca gcggtagtgt tgacgaagct cctgctcaag ttttgcggct
     9241 atctcttgat agcgtgttgg gtagctggtc ggatgtgtag acaagtgcat agatatcaat
     9301 gcctcgctta tcagataaag tgcttacgca accgttgaga gaggaaatcc agcaggctga
     9361 ccgtgacgat gataagcacc atcagggcgc aggtttgttg gaactggaaa ccgcgaatcg
     9421 cttcccacag ggtgacgccg atcccgcctg cgccgaccat gccgacgacg gtcgccgagc
     9481 ggacgttgga ttcgaagcga tagagggagt aggagatcag cagtggcatc acctgtggca
     9541 gcacgccgta gaggatctct tcgagcttgt tggcaccggt ggcgcgaatg ccttccaccg
     9601 ggccgggttc aatcgcttcc accgcttcgg aaagcagctt ggagagcacg ccggtggtgt
     9661 ggataaacag cgccagcacg ccagcacgcc agcgaacggg ccgaggccga cggcgaccac
     9721 gaacagcatg gcgaagacca tttcgttaat ggcgcggcag gcgtccatca ggcggcgaac
     9781 gggctggtaa acccaccacg gcaccaggtt ttcggcgctc atcaggccaa aggggatgga
     9841 gagaaccacc gccagcgcgg tgccccagac ggcgatttgc agcgtgacgg ccatttcggt
     9901 gaggtaatcc tgccactggc tgaaatcggg cgggaagaag tcggcggcga acgtcgccat
     9961 gttgccgccg tctttgatca gcgtaagcgg ggccatttcc gcgccctgcc acgagacgac
    10021 caacacggcg agtacaacgg cccagctcag aagcgagaac cagctgcgct tgggtggggc
    10081 gatggtgatg gtttgcatgt ttggctccgg tctgtaggcc ggataaggtg cttgcaccgc
    10141 atccggcatc aacgcctgca cattgtcgga tgcgacgccg gggcgtctta tccgacctac
    10201 gatttactgc accgctttac tcaccgaact catcgcgctt agcgcgttgt tcaggcggtc
    10261 caggtcatcc agctgcgcct gaatctcggt ggtttttgcc agcttgtcct gctcattcag
    10321 tcctttattg cttttcacgc cctgcatctc tttaaacagc gcgagctggc gaatcggcac
    10381 cagttgcagg tcgctggaag cgcggaatgg cgcccagccc aggcgttcca gcaccgcttt
    10441 ttcttccggc gttttgccgt agttcataaa gaagtcgtag atcttgtctt tggtggtttc
    10501 ggaaagattc ttgcgccaga cgatcggatc gcctgggatc agcggcgact tccagatcac
    10561 cttcagttct ttcagcttct ctggcgcgga ggttttcagc ttgtcgaggt tttcggtgtt
    10621 gttggtggca acatccacct gcttgttggc gacggccagc gcgttggttt catgcccggc
    10681 gttgacggtg cgcttgaagt cgctggcgga gatattgttt ttggcgaaga cgtagtagcc
    10741 ggggacgagg aagccagagg tggagttagg atcgccattg ccaaaggtga gatctttccg
    10801 cttcgccagc agatcgttca ggttgttgat cggactgtct ttgttgacga tcaacacgct
    10861 ccagtaaccc ggcgatccat ccgccgcgac cgtctgggcg aagacctggc cattggcgcg
    10921 atccaccgct tccatcgccg acagattgcc gtaccaggcg atatccactt tattgaagcg
    10981 catcccctgg ataatgcccg cgtagtccgg ggcaaagaag gcgttgacct tcacgcccag
    11041 cttcttctcc atatcctgca agaacggcgt ccattgcggt ttcaggtttt gctgtgattc
    11101 cgttgaaata atgccgaaat tcaacgcctt ttcctgctct tcggcgtgcg ccgggcttaa
    11161 cagggtgctg aggctgaaca tgctggtgaa ggccagcgag gcaattatct tagcgttcat
    11221 tcgttttcct caatgatggg gatgtcaggc agctttcgcg ttctcttcga cgcggttaat
    11281 gctgcggtag agatggtcaa aacgttcgtt atcaaactgt tggctgctgc cgtcgtagaa
    11341 gacgtgcccc tggcgcaggg cgacgatgcg ttcgcagtag cgcagggcgt aatccacctg
    11401 atgcagcgtg acgaccacgg tgatgccgtc gttctggttg gtgtcgcgca gggtgtccat
    11461 cacgatgcgc gctgattctg ggtccagcga ggcgatgggt tcatcggcca gaatcacttt
    11521 cgcctgctgc atcagcgcac gggcaatcgc cacacgttgc tgctggccgc cggagagggt
    11581 ggaaacgcgc tgatgggcaa aatgcaccat gccaacgcgg gtcagcgcct gtaacgcgcg
    11641 ctgtttctgc tcgccggtga accagctaaa acaggtgcgc cagaacggcg tgctgccgag
    11701 cgcgccaatc agcacgttct ccagtacgct caggcggttc accaggttga attgttggaa
    11761 tatgtagccg gtatgggcgc ggcttttgcg gatatcgcgg gccaggcggc cttcgcgctg
    11821 gactgtgcgg cccagcagct cgatatggct accgacagat ttatcgccgg taatcaaacc
    11881 gcttaagtga cgtaaaaggg tggattttcc ggaacccgac ggcccaagca gagccaccat
    11941 ttcaccgtga tgaatgttca gatcaaccgc atgcagcgcc tgatgctgat tgaaggtttt
    12001 ggcgagcttc tcgacacgga taatcgtttg catgatgcag cctccctaaa aaagtggctc
    12061 catcgtggcg gattattgtg acgatttggt taattaaaag tgactaacag atgaagagtt
    12121 aacgggaatt cgatgacagt gcgggagggc gggcctcccg gcgggttatt gcgttggttg
    12181 ttgtttgacg acattaatca tccacggtac gccaaattta tcggtgactt tgccaaagcc
    12241 atgcgcccag aaagtttcct gccaggccat ttcgattttt ccgttagcgg caagattgtc
    12301 aaaccagcgt tttccttctt cgacctgttg cgaatcgagc accagcgtaa agccggagta
    12361 gctggctttt cctgacggca tggcatcgct catcatgatg tcgcttccgg caatgcgcac
    12421 attggcgtgg gcgatggcgg tatcgggaaa ttgcattccg gaagggcagt tctcggcgct
    12481 gtcctgcgct gattttggca tttcgccgaa gctgatttta tagagcagtt ccgcgcccaa
    12541 cgtacgttga taataggcaa tcgcgtcgga acagttaccg gcaaaagaga ggtagggact
    12601 taacggcatg atggtgacct cagttaagag aagccagtta agtgtagttc gaaatttata
    12661 cagatgagag gcggcctgat aagacgcgcg agcgtcgcat caggcagt
//
LOCUS       DAPHKZ010000132        12404 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.132, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000132 DAPHKZ010000000
VERSION     DAPHKZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12404
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.132"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            108..356
                     /locus_tag="RH288_003804"
                     /pseudo
     CDS             108..356
                     /locus_tag="RH288_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611920.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            421..1572
                     /locus_tag="RH288_003805"
     CDS             421..1572
                     /locus_tag="RH288_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS30 family transposase"
                     /protein_id="HDV4032816.1"
                     /translation="MRRTFTAEEKASVFELWKNGTGFSEIANTLGSKPGTIFTMLRDT
                     GGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRR
                     YYKAVDANNRANRMAKRPKPCLLDKNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQK
                     TLRISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPI
                     HERSRNIDNRRSLGHWEGDLVSGTKNSHIATLVDRKSRYTIILRLRGKDSVSVNQALT
                     DKFLSLPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLIR
                     QYFPKKTCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD"
     gene            complement(1688..2017)
                     /locus_tag="RH288_003806"
     CDS             complement(1688..2017)
                     /locus_tag="RH288_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HDV4032817.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGE
                     MKNGEAK"
     gene            complement(2189..3247)
                     /locus_tag="RH288_003807"
     CDS             complement(2189..3247)
                     /locus_tag="RH288_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDV4032818.1"
                     /translation="MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPE
                     STWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCA
                     AAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTG
                     IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIA
                     PASKETRIPKSIYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQ
                     QILLSLVHALYEGNPQPVFANTEKLNDAVEELRQLLNNHHDLKVVETPIYGYVWLNME
                     TAHQLELLSSLICRALRK"
     gene            complement(3445..3918)
                     /gene="sbmC"
                     /locus_tag="RH288_003808"
     CDS             complement(3445..3918)
                     /gene="sbmC"
                     /locus_tag="RH288_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HDV4032819.1"
                     /translation="MNYEIKQEEKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVP
                     KEWVAVYYDNPDETPAEKLRCDTVVTVPGYFTLPENSEGVILTEITGGQYAVAVARVV
                     GDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH"
     gene            complement(4037..5203)
                     /gene="dacD"
                     /locus_tag="RH288_003809"
     CDS             complement(4037..5203)
                     /gene="dacD"
                     /locus_tag="RH288_003809"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
                     /protein_id="HDV4032820.1"
                     /translation="MKRRLIIAASLFVFNLSSGFAAENIPFSPQPPEIHAGSWVLMDY
                     TTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVF
                     VGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLH
                     LKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN
                     GLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGADSAKGREEEARKLLR
                     WGQQNFTTVQILHRGKKVGTERIWYGDKENIDLGTEQEFWMVLPKAEIPHIKAKYTLD
                     GKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA"
     gene            5412..6839
                     /gene="sbcB"
                     /locus_tag="RH288_003810"
     CDS             5412..6839
                     /gene="sbcB"
                     /locus_tag="RH288_003810"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HDV4032821.1"
                     /translation="MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIG
                     EPEVFYCKPADDYLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGY
                     NNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
                     LPSFRLEHLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLM
                     ALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVIMVDLAGDISPLLELDS
                     DTLRERLYTAKTDLGDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDNL
                     KILRENPQVREKVVAIFAEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLP
                     ALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQGYADELQML
                     VQQYADDKEKVALLKALWQYAEEIV"
     gene            complement(6882..7109)
                     /locus_tag="RH288_003811"
     CDS             complement(6882..7109)
                     /locus_tag="RH288_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HDV4032822.1"
                     /translation="MVIKKLDVVTQVCPFPLIEAKAALAEMVSGDELVIEFDCTQATE
                     AIPQWAAEEGHAITDYQQIGDAAWSITVQKA"
     gene            complement(7123..8181)
                     /gene="yeeE"
                     /locus_tag="RH288_003812"
     CDS             complement(7123..8181)
                     /gene="yeeE"
                     /locus_tag="RH288_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein YeeE"
                     /protein_id="HDV4032823.1"
                     /translation="MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIVKNNRMFYA
                     LLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIGGYIFGLGIVLAGGCATGTWYRA
                     GEGLIGSWIALFTYMVMSAVMRSPHASGLNQTLQHYSTEHNSIAETFNLSVWPLVAVL
                     LVITLWVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLS
                     EATGRMFGLGITSPTANILQFLVAGDMKYINWGVFLVLGIFVGSFIAAKASREFRVRA
                     ADAQTTLRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWIGLVFMILGVWTASW
                     LVYVRPQRKARLATAAAN"
     gene            complement(8360..9718)
                     /gene="plaP"
                     /locus_tag="RH288_003813"
     CDS             complement(8360..9718)
                     /gene="plaP"
                     /locus_tag="RH288_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HDV4032824.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(9708..9770)
                     /gene="yoeI"
                     /locus_tag="RH288_003814"
     CDS             complement(9708..9770)
                     /gene="yoeI"
                     /locus_tag="RH288_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HDV4032825.1"
                     /translation="MGQFFAYATVITVKENDHVA"
     gene            complement(9985..10914)
                     /locus_tag="RH288_003815"
     CDS             complement(9985..10914)
                     /locus_tag="RH288_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4032826.1"
                     /translation="MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESD
                     LNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIEAFYQHHSVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFG
                     FSRLGDLEQVFAVAPHHPLALEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQ
                     TAGLASGWWRDEILANSAIAGVYAKSDDGKSAI"
     gene            complement(10960..11784)
                     /locus_tag="RH288_003816"
     CDS             complement(10960..11784)
                     /locus_tag="RH288_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV4032827.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEAARMSG
                     IDSYLLRMEPELVCDSDDLDALMDADALVITLPARRSGPGDEFYLQAVQELVDSALAH
                     RIPRIIFTSSTSVYGDAQGTVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMARLLGLEPPQFRNSLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE"
     gene            complement(11867..12121)
                     /gene="yoeB"
                     /locus_tag="RH288_003817"
     CDS             complement(11867..12121)
                     /gene="yoeB"
                     /locus_tag="RH288_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /protein_id="HDV4032828.1"
                     /translation="MKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGK
                     PEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAACRYHY"
     gene            complement(12118..12369)
                     /gene="yefM"
                     /locus_tag="RH288_003818"
     CDS             complement(12118..12369)
                     /gene="yefM"
                     /locus_tag="RH288_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoeB-YefM toxin-antitoxin system antitoxin YefM"
                     /protein_id="HDV4032829.1"
                     /translation="MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEE
                     YNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKDIIE"
BASE COUNT         3385 a         3170 c         2866 g         2983 t
ORIGIN      
        1 catcacgtat ttatatatca tgaagctatt gttgtgtttt gtactgaatc gccacgggtt
       61 taacagacac ctcagagtca tttaagatgg cttaaagaga agtgcccatg agcggtaagc
      121 gttatcccga agagtttaaa actgaagcag tcaaacaggt tgttgatcgc ggttattctg
      181 ttgccagcgt tgcaacacgt ctcgatatca ccacccacag cctttatgcc tggataaaga
      241 agtacggtcc ggattcttcc actaataaag aacagtcaga tgctccggcc gagatccgcc
      301 gtctccagaa agagctgaaa cgggttaccg acgaacggga catattaaaa aaagccgctg
      361 tagattcaat tggtcaacgc aacagttatg tgaaaacatg gggttgcgga ggttttttga
      421 atgagacgaa catttacagc agaggaaaaa gcctctgttt ttgaactatg gaagaacgga
      481 acaggcttca gtgaaatagc gaataccctg ggttcaaaac ccggaacgat cttcactatg
      541 ttaagggata ctggcggcat aaaaccccat gagcgtaagc gggctgtagc tcacctgaca
      601 ctgtctgagc gcgaggagat acgagctggt ttgtcagcca aaatgagcat tcgtgcgata
      661 gctactgcgc tgaatcgcag tccttcgacg atctcacgtg aagttcagcg taatcggggc
      721 agacgctatt acaaagctgt tgatgctaat aaccgagcca acagaatggc gaaaaggcca
      781 aaaccgtgct tactggataa aaatttacca ttgcgaaagc ttgttctgga aaagctggag
      841 atgaaatggt ctccagagca aatatcagga tggttaaggc gaacaaaacc acgtcaaaaa
      901 acgctgcgaa tatcacctga gacaatttat aaaacgctgt actttcgtag ccgtgaagcg
      961 ctacaccacc tgaatataca gcatctgcga cggtcgcata gccttcgcca tggcaggcgt
     1021 catacccgca aaggcgaaag aggtacgatt aacatagtga acggaacacc aattcacgaa
     1081 cgttcccgaa atatcgataa cagacgctct ctggggcatt gggagggcga tttagtctca
     1141 ggtacaaaaa actctcatat agccacactt gtagaccgaa aatcacgtta tacgatcatc
     1201 ctcagactca ggggcaaaga ttctgtctca gtaaatcagg ctcttaccga caaattcctg
     1261 agtttaccgt cagaactcag aaaatcactg acatgggaca gaggaatgga actggccaga
     1321 catctagaat ttactgtcag taccggcgtt aaagtttact tctgcgatcc tcagagtcct
     1381 tggcagcggg gaacaaatga gaatacaaat gggctaattc ggcagtactt tcctaaaaag
     1441 acatgtcttg cccaatatac tcaacatgaa ctagatctgg ttgctgctca gctaaacaac
     1501 agaccgagaa agacactgaa gttcaaaaca ccgaaagaga taattgaaag gggtgttgca
     1561 ttgacagatt gaatctacag ttgctaattt cgataggttc tcagatgaga atgatgacgg
     1621 tgatacacag ataagaatca atgagcaatg agggttgccg ggcaaccctc attgaataaa
     1681 acaggaatta cttcgcttcg ccgtttttca tttcgcccat agctttcagc tttttggaga
     1741 tatcgcggcg ttctttggag agctcggcat ttttgatgat gtaatcgtca acgcgatctt
     1801 catagtcacc tttcatgctg gcgatgatgc cctggattgc ttcaacgctc atcccgggct
     1861 tgatgtaatc gctcaggttg tccagcaaca ggacgcgctt ctggttgtca cggatctttt
     1921 tctcaacgtc ctgaatttca cgttgcagtt tgttcttacg acggaacaga cgaacaaatt
     1981 ccagtacgtc ctggaatgaa ggcttggtag tttccatttt tatacccctg ataatgtgag
     2041 agtcggattc gtttaagcaa ccgctattcg ttagggccaa cattactcat agctgccgca
     2101 gatgacaatg cttttatccc ttttcactat catacccttt atccttgctg aatcgaagca
     2161 gcagcaagat gattctgaag ttcaggaatt atttgcgcaa ggcccggcaa atcagactcg
     2221 atagcaactc aagctgatgt gccgtttcca tgttcagcca cacataacca tagattggtg
     2281 tttccacaac cttcaggtca tggtggttat tcagcaactg acgcagctct tccacagcat
     2341 cgttcaattt ttccgtattg gcaaaaaccg gctgcggatt accttcgtac agcgcatgaa
     2401 caaggctcag cagtatttgc tgcatcatgt gctgggtatc acgaagtttt tgcgcgttca
     2461 ataacacgaa atggctgggg cgcgtggccc agtatgcatt gatttgcaac tccagcatac
     2521 aaaccagatt gcggttaatg gtctggatac cttcatatat cgattttgga atacgagttt
     2581 ctttgctggc gggcgcaatc agtccacgca ttttcacggc atcggtcagg agtttttgta
     2641 gatggctttc cagacgtggg cgttcgagta agttcggtga gaatgcagat tgatagaccc
     2701 gattatactc ggtcagactt ttcgccagtt gaatgcgcca gtggatgaac gcccgttgtg
     2761 gccagatacc ggtaaacaac attgccagta aagagccgag gatcacatcg ccgcttcgcc
     2821 ataacgccgt atcaatttca cctgtcgggg aacccacaac aattgccagc gtcaccccaa
     2881 tcaataaacc ttgatacggt ttcttgccca gcgccagcca accgcaaagg aacatggccg
     2941 ccgcgcacca gactaacatc agcggtaacg agattaactc cagttgcaga gcgataagac
     3001 ctaaaatcga acccaacacc gtaccgccaa tacgctcaaa ggcgcgaggg acaacgttac
     3061 cccagaacga gattggcccc ataatcacca ccatggtgac cagcggccag gtgctttccg
     3121 ggatagtaaa caggcggata atgagaaaag tgagcaggaa tgccagcgcg acccgagtac
     3181 catgcacaat gcggtaatgg cggtataccc ggatttcaaa cgggcttaat gacttatcgg
     3241 cacgcacgca gaaactccgt aatgagatta aaagcgctca taactcatct gtcggccaga
     3301 aggcgcgcct ctgaattatc cgacggacaa accgggaaca gtgtaatttc ccggcaggag
     3361 cgaaaaaatt gaaaggcgca tcttactctt ttcgctttca aaaaaaagag tggtcatcgc
     3421 gttaacacac cgccctgaga tgaattagtg atgttttggc tgcaccgcaa catacatttc
     3481 gatatcccag tacccatctt ccgcgccatt gttcaaataa acctcgaagc agggctttgg
     3541 taacatttca taagcactgt cctgcaagag actattaaag aactgatacc agggtttagc
     3601 aaaatcatca ccgactacac gagctaccgc caccgcatac tgaccacctg taatttctgt
     3661 cagaatgacg ccctcactgt tttcgggaag cgtaaagtaa cccggcaccg tcacgacggt
     3721 gtcgcagcgt aatttttcgg cgggtgtttc atctggattg tcgtaataga cagcaaccca
     3781 ctccttcggc acaatatttt tgctatctac ccacatcatc aactgctcaa agcctttctt
     3841 taccgtctgt tcccacgggc caacgagatg gaaacctgca acggtacgtt tctcttcctg
     3901 cttaatctcg tagttcatga cgcctccatt gatactgttt ttatatacag tatagttgca
     3961 aaattaaaac cacaaggaat gagtgttgat tatgcgagca gactcgcact cctgccagtc
     4021 tgctgcaaaa gaaaggtcag gccttatggt ggaaataatc actcaggcga gaaaacatgc
     4081 tgccttcccc gacagattcc agggtaacca gcggccagtg cgccacctgt ttatcacggt
     4141 cgtaaagttc aatttcccct acccgctgat gggcgctaat tggcgcggtg agttctttac
     4201 catcaagggt atatttggct ttgatatgtg gaatttcggc tttcggtagc accatccaga
     4261 actcttgttc cgttcccagg tcgatatttt ctttatcgcc ataccagatg cgttccgttc
     4321 cgaccttttt cccacggtgc aaaatttgca ccgtagtaaa gttttgttgc ccccaacgca
     4381 gtaattttct tgcctcttcc tcacgacctt ttgcactgtc agcccccatt accactgcaa
     4441 tgagacgacg ctgcccatct acagccgaag caatgagatt aaacccggca ccagaagtat
     4501 gacccgtttt caggccgtca acattcatgg ttttatccca caacaacccg ttacggtttt
     4561 gctgggtgat accgttccag gtgagacttt tctcactgta catatgataa aactcgggct
     4621 cgccgtggat gatagcacga gaaagcacag ctaaatcata agccgagcta tgctggccag
     4681 gtgcatccag accatgcact gtttcaaaat gcgtatcctt gagatgcagc ttctcggcat
     4741 agttgttcat catttcaaca aactgccgtt gcccaccggc aatatagtca gccagagcaa
     4801 cacaagcgtc atttccggaa tccacaatta aaccacggct taaatcacgt accgatacgc
     4861 gatcgccctc tttcaaaaac atcagtgaag aaccgacaaa caccggatta tctttcgccc
     4921 acgcatcgcg ccccacggtg acaatatcgt ctggcgtaat gcgatgacta tcgatagcgc
     4981 gatccacgac ataacccgtc atcagctttg tcaggctggc gggattgcgc tgttgatgct
     5041 cattacccgc ggtgaggatc tgaccggtgg tgtaatccat caatacccag gacccggcat
     5101 gaatctctgg aggctgaggt gaaaaaggaa tgttttccgc cgcaaaacca gacgataagt
     5161 taaaaacgaa caaagaagca gcaataataa gacggcgttt caacagcaaa ccctcaggag
     5221 tttcaaatag ctgttctttt tacggaaata cttatgaact ggctggaata aagtgcaaga
     5281 aaatgtgact accctctcat ttttatctga catgatctgt tgccactcgc tgccaaattg
     5341 tggcgctaaa gctgattagc acggtgatat ttgatactct ggcagacagc agaaataacg
     5401 gatttaacct aatgatgaat gacggtaagc aacaatctac ctttttgttt cacgattacg
     5461 aaacctttgg cacgcacccc gcgttagatc gccctgcaca gttcgcagcc attcgcaccg
     5521 atagcgaatt caatgtcatc ggcgaacccg aagtctttta ctgcaagccc gctgatgact
     5581 atttacccca gccaggagcc gtattaatta ccggtattac cccgcaggaa gcacgggcga
     5641 aaggagaaaa cgaagccgcg tttgccgccc gtattcactc gctttttacc gtaccgaaga
     5701 cctgtattct gggctacaac aatgtgcgtt tcgacgacga agtcacacgc aacatttttt
     5761 atcgtaattt ctacgatcct tacgcctgga gctggcagca tgataactcg cgctgggatt
     5821 tactggatgt tatgcgtgcc tgttatgccc tgcgcccgga aggaataaac tggcctgaaa
     5881 atgatgacgg tctaccgagc tttcgccttg agcatttaac caaagcgaat ggtattgaac
     5941 atagcaacgc ccacgatgcg atggctgatg tgtacgccac tattgcgatg gcaaagctgg
     6001 taaaaacgcg tcagccacgc ctgtttgatt atctctttac ccatcgtaat aaacacaaac
     6061 tgatggcgtt gattgatgtt ccgcagatga aacccctggt gcacgtttcc ggaatgtttg
     6121 gagcatggcg cggcaatacc agctgggtgg caccgctggc gtggcatcct gaaaatcgca
     6181 atgccgtaat tatggtggat ttggcaggag acatttcgcc attactggaa ctggatagcg
     6241 acacattgcg cgagcgttta tataccgcaa aaaccgatct tggcgataac gccgccgttc
     6301 cggttaagct ggtgcatatc aataaatgtc cggtgctggc ccaggcgaat acgctacgcc
     6361 cggaagatgc cgaccgactg ggaattaatc gtcagcattg cctcgataac ctgaaaattc
     6421 tgcgtgaaaa tccgcaagtg cgcgaaaaag tggtggcgat attcgcggaa gccgaaccgt
     6481 ttacgccttc agataacgtg gatgcacagc tttataacgg ctttttcagt gacgcagatc
     6541 gtgcagcaat gaaaattgtg ctggaaaccg agccgcgtaa tttaccggca ctggatatca
     6601 cttttgttga taaacggatt gaaaagctgt tgttcaatta tcgggcacgc aacttcccgg
     6661 ggacgctgga ttatgccgag cagcaacgct ggctggagca ccgtcgccag gtcttcacgc
     6721 cagagttttt gcagggttat gctgatgaat tgcagatgct ggtacaacaa tatgccgatg
     6781 acaaagagaa agtggcgctg ttaaaagcac tttggcagta cgcggaagag attgtctaat
     6841 ttgaagcctc cgccgctggt acggcggagg acaatgttga gtcaggcttt ttgaacggtg
     6901 atgctccacg ctgcatcgcc aatctgctga taatcggtga tggcatgtcc ttcttctgcc
     6961 gcccactgtg ggattgcttc agttgcctgg gtgcaatcaa actcaatcac taactcatcg
     7021 ccgctgacca tttctgccag agctgctttt gcttctatga gtggaaacgg acagacctgc
     7081 gtcaccacat ccagcttttt aatcaccatc tttacacctt acttaatttg ccgcagcagt
     7141 tgccagtcgc gccttacgct gcggtcgaac atacacaagc caggacgcag tccagactcc
     7201 gagaatcata aatacaaggc caatccagcc ctgccaggtc atcattgcag tcataaccag
     7261 tccattaccg atagagcaac cacctgcaat actggcaccg aagcccatca gtacaccacc
     7321 taacccgcta cgtaatgttg tttgtgcatc agctgcgcga acgcggaact cacggctcgc
     7381 tttggctgca ataaatgacc ccacgaagat ccctaacacc aggaaaacgc cccagttaat
     7441 gtatttcatg tcacccgcga ccagaaattg cagaatattg gccgttgggg aagtgattcc
     7501 taacccaaac atgcgtccgg ttgcttcact caggggccag gctaaaagcg caatcaaacc
     7561 gatgagtaca gctgtgacaa agggatgcca gcgtttttca aacagaatat gagcgatccc
     7621 ggttcggcgc ggcggtaagg tcgcgacttt gagttttggc ttcttcaact ctttcatcac
     7681 cacccagagc gttatcacca gcaaaacggc aaccaacggc cacacagaca aattaaaagt
     7741 ctcagcaata gagttatgtt cagtactgta gtgctgcaag gtttgattta aaccactggc
     7801 atgtggagaa cgcatcaccg cactcatcac catataagtg aaaagcgcga tccaactgcc
     7861 gatcaatccc tcacccgcgc gataccaggt cccggtggca catccacccg ccagaacaat
     7921 tcccagcccg aagatatacc cacctataac agtaccaagc cacgggaacg ccccggcttc
     7981 gtaagtcagt aggcccgcct gaattaacgc aaaaaccccc acgctttgta ccgaaattgc
     8041 aatcagcaag gcgtaaaaca tgcgattatt tttcacgata tacatatcgc gaaaaccacc
     8101 tgtcaggcaa aaacgcccac gctgcatgac aaatcccagc agagcaccac aaattagccc
     8161 gcttaatatc attgaaaaca taaattaatt aaccagatga atgttaatga ggaaattatt
     8221 catgactggt ggaatgcaga ccaataacca aattctctaa attagaacaa atggttatta
     8281 atgaggagtt cgatacaaaa gaataaaaaa accggagcca aatgttcatt cgactccggt
     8341 ttattattag aaaagatgat tatgctacgt cttcgtactg cggaaccgga ttacggaagc
     8401 tcttggtgac gcaagccagg taaatcagac cgatagcagc ccagatcaga cccagaacca
     8461 ttgagctttc ttccaggtta acccacagcg caccaacggt cagcgcacca cacatcggca
     8521 ggaacagata ctggaagtga tctttcagcg tcttgttacg cttctcacgg atccagaact
     8581 gcgagatgac cgacaggtta acgaaagtga acgccaccag cgcaccaaag ttaatcagcg
     8641 ccgttgccat taccaggtcg aagttgattg ccagcagggc aatcgcgcca accaggatga
     8701 tgttcatcgc cggagtacgc catttcgggt gtacataacc gaagaagctt ttcgggaata
     8761 cgccgtcacg acccattacg tacatcagac gcgctacgcc tgcatgcgcc gccataccgg
     8821 acgccagtac ggtaatggtg gagaagatca gcgcgccaac ctggaacgct ttacccgcaa
     8881 cgtacagcat gatttcaggc tgtgacgcat ccggatcttt aaagcgagag atatccggga
     8941 agtacagctg caggaagtaa gttgcaaaga tgaagatcat gccgccgatc agcgcggtca
     9001 ggaaaatcgc acgcgggatc acgcgctctg catctttggt ttcttccgac aggttgctga
     9061 tgccgtcaaa gccggtaaag gagaagcaca ggattgtcgc cccggtaatc atcgggataa
     9121 catgcgcatc gccagaccag aatggacgag tgctcgccag cgtaccagcg ccttcacctt
     9181 caaatacgcc ataaacaacc atgcccagaa tcaccgcgat cagcactacc tgcaacacga
     9241 cgattacagt gttgaagttc gctacggatt tcagactacg caggttaaag gcggtcataa
     9301 aggccaccag cgccaccaca aacatccacg atgggatgga aggcaccaga gcttcaaaat
     9361 agattttcgc cagtagaatg ttgatcatcg gcgcgaacag atagtcgagc agagaagacc
     9421 aacccaccat aaagccgaca gtcgggctaa tggatttctg ggcgtaagtg tatgcagagc
     9481 cagcagaagg atagcggcga accagcttcc cgtagctcag agccgtaaac aggatcgcaa
     9541 tcaatgcgaa cgcataggct gtcggcacat gaccatccgt gaggcctgaa acgataccaa
     9601 aagtatcaaa cagcgtcatc ggctgcatat aggcaagacc catcattaca accggaacta
     9661 acgtaagcgt tttacgcaat tccacgcgag aggtgtttgg agtaacgtta tgcgacatgg
     9721 tcattctcct ttacggtgat aaccgtcgcg taagcaaaaa attgccccat ttttttggat
     9781 tcctcagcga caacaactgt cgatttttag taaatatcta tccggtacga agcccggcct
     9841 cttggtatga atgattggtt tgaagcaaaa aataaccgac gctgatgaaa cgtcggtttt
     9901 tagtcatttt ttgacagcgg cgcattgtgc ctaaatgggg gggaaatgac aagagaatga
     9961 gaggcttgtc agaataattt ttctttaaat ggctgatttt ccgtcatcag attttgcata
    10021 aacaccggcg atcgcactat ttgctaaaat ttcatcccgc caccagccac tggcaagtcc
    10081 tgcggtctgt tcgttccagc caatccagac gggttcaaag agagtttggg cgaccacttt
    10141 cttctcgatt aacgcgccac tatcgagaaa acgttgcgcc agataacggg gtaaatagcc
    10201 gcagccgagg ccgctaattt gcagctccag tttggtttta aaatcgaaaa cggtaatggc
    10261 ttcttgttcg tcgagaagtt gtgatgccgt agaagcgcct gcctgcgcag tatcccccac
    10321 cacaatcgcc cgatatcgct taataatacg acgatttaac ggctcttctt ccagggctaa
    10381 cggatgatga ggcgcgaccg caaagacttg ttccagatcg cccaaccgtg aaaaaccaaa
    10441 ctcactggaa gatggtggct catgcatcgc gccaacaata atatccgctc gcccctgagt
    10501 cagggcatcc catgaaccac cgagtacgcc attgataaac ttcaggcgcg tcacgctatg
    10561 atgttgataa aaagcttcaa tgagtggcgc aagcagagaa aaaggaaacg tgtcgtccac
    10621 gccaatcacc agctcgtttt cccagccttc atgcagtttg atcgcctgct tttccagttc
    10681 ccgcacggta tgcagaactt cccgcccttt ctctaataac atttttccgg tgcgggtgaa
    10741 tttagcgcgg tgtccgctac gatcaagcaa ttgaatatta aggtcgcttt ccagcttgtg
    10801 aacggtgtaa ctcagagcgg acggcgtctt gtagagtttg gccgacgccg ccgcaaaact
    10861 gccttctttt tctaaggcat cgaggatcat caacacatcc agcagtggtt tcatacacgc
    10921 ccccttgcag tgcatgcggc gtcctgctgg cgtgatcgtt tactccagcg gcattaccag
    10981 cggatcggga tactggtatt caaatcccag ttcattacaa atccgactgc catcaataat
    11041 cttacctttg ccgctgtcca gactatttct gaactgcgga ggttccagcc ccagtaaacg
    11101 ggccatctgc ggatagaaaa cattacgcgc agggtgagct ggcgcacata tattatagat
    11161 gtgtccgcct ttaggtgcct gtaacaacag agtgatagcg ccaataacat cttctaaatg
    11221 gactaaatta acaccatgtt caccatcagg cgcggttttt ccggcaaaga agcgtccggg
    11281 atgacgtccc ggtccgacca ggcccgcaag acgcagaata tcgaccgaag taccgggtaa
    11341 attgtgcagc cagtcttcga gttcttctaa tactcgtcca ctgttggtta ctggattacg
    11401 cggggtggtt tctttcaccg tgccttgcgc gtcgccatag acagatgttg agctggtaaa
    11461 aataatgcgg ggaatacgat gggccagcgc gctatccact aactcttgta ccgcttgtaa
    11521 atagaactca tcgccggggc cgctacgacg tgccggaagc gtaatgacca gcgcatcggc
    11581 atccatcagg gcatccagat cgtcagaatc gcaaactagc tcaggctcca tgcgaagcag
    11641 atagctatca atgccactca ttcgggccgc ttcgacacca tcttgtgtgg ttttactccc
    11701 ggtgacttgc cagcctcgcg ctgaaagtga catcgccagc ggcatgccta accaccctaa
    11761 cccgacaatt gcgacctttt tcatccgtta tctcctgata caccttagat ctataaggct
    11821 acgctagcgt atcaaaactg acaattcatt ctatgaatga atctgttcaa taatgataac
    11881 gacatgctgc aatgagcagt gaatcgtcgg taaccgcgta taccagacgg tgctcctctg
    11941 taatgcgtcg ggaccagaaa cctgacaaat tatgtttcag gggttctggc ttccccttac
    12001 cttcaaatgg cgttctgcgg gtatctttga taagttcatt gatcttttta acaattcgct
    12061 tatctgtttc ctgccagtac agataatcgt cccatgattc ctcagaccag attagtttca
    12121 ctcaatgatg tccttttccg ttcctttgcc tgatttcagg ctatcgattg agtccatcaa
    12181 tctccgggcg ttagcggggg agcgcagtag ataagccgtc tcttccagcg agttgtattc
    12241 ttcgagtgac atcagaacac aagcctctcc attctgacga gtaataagga tcggggcatg
    12301 atcttcaacg gctttcatca ttgttgccga caaattctga cgcgcttcgc tgtagctaat
    12361 tgtacgcatg tcaatctcct cttttgtaca gttcattgta caat
//
LOCUS       DAPHKZ010000133        12371 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.133, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000133 DAPHKZ010000000
VERSION     DAPHKZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12371
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.133"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..94)
                     /locus_tag="RH288_003819"
     CDS             complement(<1..94)
                     /locus_tag="RH288_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HDV4032830.1"
                     /translation="MTIEKHERSTKDLVKAAVSGWLGTALEFMDF"
     gene            complement(152..1171)
                     /locus_tag="RH288_003820"
     CDS             complement(152..1171)
                     /locus_tag="RH288_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HDV4032831.1"
                     /translation="MKSILIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNV
                     CTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTE
                     NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPL
                     GEIFTEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKE
                     LSIFSSRLNANKFPIVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVL
                     LTFSE"
     gene            complement(1183..2397)
                     /gene="rspA"
                     /locus_tag="RH288_003821"
     CDS             complement(1183..2397)
                     /gene="rspA"
                     /locus_tag="RH288_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HDV4032832.1"
                     /translation="MKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYG
                     MSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGDKPGLGIEFDEKLAAKYPYEPAYLP
                     VARLEDGTLWNW"
     gene            complement(2603..2929)
                     /locus_tag="RH288_003822"
     CDS             complement(2603..2929)
                     /locus_tag="RH288_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HDV4032833.1"
                     /translation="MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIV
                     AGWGRT"
     gene            3064..3405
                     /locus_tag="RH288_003823"
     CDS             3064..3405
                     /locus_tag="RH288_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HDV4032834.1"
                     /translation="MKITLSKRIGLLAILLPCALALSTTVHAETNKLVIESGDSAQSR
                     QHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVITP"
     gene            3440..4000
                     /gene="speG"
                     /locus_tag="RH288_003824"
     CDS             3440..4000
                     /gene="speG"
                     /locus_tag="RH288_003824"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HDV4032835.1"
                     /translation="MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFSVEGELMHEFFINGQYRNAI
                     RMCIFQHQYLAEHKTPGQTLLKPTAQ"
     gene            complement(4003..4713)
                     /locus_tag="RH288_003825"
     CDS             complement(4003..4713)
                     /locus_tag="RH288_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HDV4032836.1"
                     /translation="MKYKLLPCLLAIFLTGCDRTEVTLSFTPEMASFSNEFDFDPLRG
                     PVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTVVALVLDANYYRDAET
                     LEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKS
                     NDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDSHANPVDCQLIIVDEG
                     VKPAVERVYTIKNTIDYY"
     gene            4821..5126
                     /locus_tag="RH288_003826"
     CDS             4821..5126
                     /locus_tag="RH288_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416103.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
                     /protein_id="HDV4032837.1"
                     /translation="MKLSTCCAALLLALASPAVLAAPGSCERIQSDISQRIINNGVPE
                     SSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRTTSGNVSAPAQSSQDGAPAEPQ"
     gene            5325..7751
                     /locus_tag="RH288_003827"
     CDS             5325..7751
                     /locus_tag="RH288_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HDV4032838.1"
                     /translation="MSKNERMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRNAAAAV
                     QQAREKVVWGACSVNCGSRCALRLHVKDNEVTWVETDNTGSDEYGNHQVRACLRGRSI
                     RRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYS
                     SGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTD
                     IENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWL
                     PIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGE
                     GDDKTAKTPQWASQITGIPEDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIA
                     MLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTA
                     IRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTS
                     SAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKR
                     LGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYK
                     AFRDDPEANPLKTPSGKIEIYSSRLAEIARTWELEKDEVISPLPVYASTFEGWNSPER
                     RTFPLQLFGFHYKSRTHSTYGNIDLLKAACRQEVWINPIDAQKRGIANGDMVRVFNHR
                     GEVRLPAKVTPRILPGVSAMGQGAWHEANMSGNKIDHGGCVNTLTTLRPSPLAKGNPQ
                     HTNLVEIEKI"
     gene            7812..10235
                     /locus_tag="RH288_003828"
     CDS             7812..10235
                     /locus_tag="RH288_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416105.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HDV4032839.1"
                     /translation="MKIHTTEALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVR
                     AAEAPVEEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGDDVYGNHQVRACLRG
                     RSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVHV
                     LYGTGVDGGNITNSNVPYRLMNSCGGFLSRYGSYSTAQISAAMSYMFGANDGNSPDDI
                     ANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLP
                     IRPGTDGALACAIAWVLITENMVDQPFLDKYCVGYDEKTLPANAPRNAHYKAYILGEG
                     PDGIAKTPEWAAKITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTSRAIAM
                     LSVLTGNVGINGGNSGVREGSWDLGVEWFPMLENPVKTQISVFTWTDAIDHGTEMTAT
                     RDGVRGKEKLDVPIKFLWCYASNTLINQHGDINHTHEVLQDDSKCEMIVGIDHFMTAS
                     AKYCDILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWMLSEVAKRL
                     GPDVYQTFTEGRSQHEWIKYLHAKTKERNPEMPDYEEMKTTGIFKKKCPEEHYVAFRA
                     FREDPQANPLKTPSGKIEIYSERLAKIADTWELKKDEIIHPLPAYTPGFDGWDDPLRK
                     TYPLQLTGFHYKARTHSSYGNIDVLQQACPQEVWINPIDAQARGIRHGDTVRVFNNNG
                     EMLIAAKVTPRILPGVTAIGQGAWLKADMFGDRVDHGGSINILTSHRPSPLAKGNPSH
                     SNLVQIEKV"
     gene            10246..10863
                     /gene="dmsB"
                     /locus_tag="RH288_003829"
     CDS             10246..10863
                     /gene="dmsB"
                     /locus_tag="RH288_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HDV4032840.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
                     KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV"
     gene            10865..11719
                     /locus_tag="RH288_003830"
     CDS             10865..11719
                     /locus_tag="RH288_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HDV4032841.1"
                     /translation="MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIV
                     RGMFFLWLLMGVGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWL
                     VAVIGKMPQALGKLWLLFSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
                     GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVP
                     DYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHM
                     TVGMAIAG"
     gene            11762..>12371
                     /gene="dmsD"
                     /locus_tag="RH288_003831"
     CDS             11762..>12371
                     /gene="dmsD"
                     /locus_tag="RH288_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HDV4032842.1"
                     /translation="MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWET
                     QWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
                     RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLF"
BASE COUNT         3232 a         3116 c         2989 g         3034 t
ORIGIN      
        1 tgaaatccat aaattcaagc gcagtgccca gccatcccga tactgctgct ttcaccaaat
       61 ccttagtgct tctttcgtgt ttttctattg tcataatggt tatctctaaa aaagaggtaa
      121 gatgcgtact acttactcgc cgttattggt attattcaga aaaagtgagt aagactttgc
      181 agcaatgttt ttgatcctgt tcaaataaac taatggcatc agcaacatgc tggaaatcaa
      241 acgtatgggt aattaatttt tctggtttaa ttaacccttt acttaaccag tcgataacga
      301 tcgggaattt atttgcattt aagcgtgaag agaaaataga gagttctttt ccggtaattc
      361 cttgctgaat cacttcagac ggttcactgg agaaccccat caatacaata cgtgccgctg
      421 gagaagccag cgttacggcc tctttcagga tagaaggatg acaagccgca tcgataatta
      481 atgtcggctt gatgcctttt tcagtgaaaa tctcgccaag cggtgtctgg ctgttattaa
      541 tcgcccagtc agccccgctc tctttcgctt tttccagtcg ttcatcaatg cgatcggcaa
      601 caatcacatt tttaacgtta tagacgcctt ttaatacctg aacgatcgtc aggccgattg
      661 gaccggcacc ataaaccaga acggtatcat tttcagtcgg ttgaccatgt ccggttacgt
      721 tagccgcaat ggtaaaaggt tcgatcatta ccgcatattg atcggccact gcttcaggaa
      781 ttttccacgc attttttgcc ggaaccacgg catattcact gaaaccaccg tcagcgtgca
      841 cacctaatac agccagtgtc gtacaaacgt tcggtttacc tatagagcac ggatagcaat
      901 gcccacagct gaccaccgga tcgacagcaa cacgttcacc gactctggcg ctttccacgc
      961 cttcacccac tgcatcaatg acgccaaaga attcatgacc aatgacgcgc ggatatttcg
     1021 caaaaggatt atgcccacga taaatatggc tatctgaacc acaaattccg gcaagtttca
     1081 cttttactcg tacttcaccc gctgacgggg tgggtatttc acgttcgaca atcgccagtt
     1141 gattcggttt ttcaattaat atgcttttca ttatcttact ccttaccagt tccacagcgt
     1201 gccatcttcc agacgtgcga ctggtagata agcaggttca tagggatatt tcgccgccag
     1261 cttttcatcg aattcgatac caagacccgg tttgtctccc ggatgcatat agccgttatc
     1321 gaaagtccag ttgtgcggga agacttcgag catttgttcg gaataaccca tgtattcctg
     1381 gacaccgaaa ttggggaccc acagatcaaa gtgcagcgcc gcagccatgc agactggtga
     1441 caaatcggaa ggaccgtgtg agccagtacg tacctgatac agcgaagcaa aatcggcaat
     1501 ccggcgcata ccggtaattc cgcctgcatg ggtcagcgtg gtgcggatat aatcgatgag
     1561 ttgctcttca atcagttgtt tgcagtccca gatgctgttg aagacttcac ccactgcgat
     1621 gggtgtgacg gtatgttggc gaatgagacg gaagcattcc tggttttccg caggcgtcgg
     1681 gtcttccatc cagaacatgc gataatcttc aatgctttta ccaaagcgcg ccgcttcaat
     1741 aggcgttaag cgatggtgca tgtcatgcag caaatgttca ttaaaaccaa acttgttacg
     1801 taccgcgtca aacaatttcg gcatgaaatc gaggtatttc tccgtcgacc acagctgctc
     1861 ttccggccac tgtcctttgg ttgcgggttc ataagccaga cctttacctt tcgacatgcc
     1921 gtaggtggtt ttcataccag ggattccgca ctgcacgcgg atggctttga atccaagctc
     1981 ttgatgacgg gcataatcat ccagagcttc atcaatactg tgaccggtgg tatggcaata
     2041 aaccatcacc ccttcacgag acgcgccgcc gagtaactgg taaagcggca tgttggcagc
     2101 tttggcttta atatcccaca gcgccatatc aaccgctgaa atggccgaca tcgtaaccgg
     2161 accgcgacgc cagtaagcac ctttatagaa aaactgccag atatcttcga tacggtgcgc
     2221 atcgcgacca ataagctgcg gacaaaggtg atcctgcaaa taagaggcca cggaaagctc
     2281 acgtccattg agggtggcat ccccaaggcc cgtaataccg tcctcagtgg tgatttttaa
     2341 tgtgacgaaa ttacgccccg gacaggtaac aaaaacttca gcctttacga tcttcatgtt
     2401 cgattccttg catcgcttgt cgtgatgcat gaaatctacg caactgagct gctaccatac
     2461 aagtataaag atcgaaaaaa gccggagtga tcacaaaaaa aggcgtatat ttgcgctgtg
     2521 aatggttgac aaaagatgaa atagaatacc ttttgtcagc tgacacttcc tcttatctta
     2581 ttgataaaat ggatttatgt tcctacgtgc gcccccagcc cgcaacaatg atcaacatgc
     2641 cgcaaagcgc aatcaacgca cccgtccagt cataaagagt cagtttcacg ccatccacaa
     2701 cgcgcagcca catcaacgcc gtgcagacat aaacgccacc ataagccgcg taaacacgcc
     2761 cactcgccgc tggatgcaac gttaacaacc agacaaacag cgccagtgaa atccccgccg
     2821 gaagcaacag ccagatactg gcgtttcgtt ttaaccacaa ccagggcaga aagcatccaa
     2881 taatttcaca cagcgcagta gcaaaaaata gtaacgttgt tttaatcatc tttgtctctt
     2941 attgacatca tgtatagtta tagggcgaca taatatcatc aatataaaca ccctcctggt
     3001 acgttttgcg tccgcagtgg atggtgtaga atcaccttta atcattcata cagggaatga
     3061 attatgaaaa tcactctcag caaacgaatc ggcctgctcg ctattctgct gccttgcgca
     3121 ctggcattga gcacaactgt tcatgccgaa actaacaaac tggtgattga gtctggcgac
     3181 agtgcacaaa gccgccagca cgccgctatg gaaaaagagc aatggaatga cacgcgcaat
     3241 ctgcgccaga aagtgaataa acgcactgaa aaagagtggg ataaagccga cgccgctttt
     3301 gataaccgcg ataaatgtga gcaaagcgcc aacatcaatg cctactggga gcccaatact
     3361 ttgcgctgcc tggaccgtcg aactggccgc gttattaccc cctaacctgt tattgattta
     3421 aggaatgtaa ggacacgtta tgccaagcgc ccacagtgtt aagctacgcc cgctggagcg
     3481 tgaagattta cgctatgtac atcaactcga caataacgcc agtgtgatgc gttactggtt
     3541 tgaggaaccc tacgaagcct ttgttgaact ctctgatctg tatgataagc atattcacga
     3601 tcagagcgaa cggcgctttg tggtggaatg tgacggcgaa aaagccggtc tggtggagct
     3661 ggtggaaatt aaccatgttc atcgccgcgc agaatttcag ataattatct ccccggagta
     3721 tcaggggaaa ggtctggcaa cccgtgccgc caaattagca atggactatg gctttaccgt
     3781 tctcaatctc tataagctgt atctgatcgt tgataaagag aatgaaaaag cgattcacat
     3841 ttaccgcaag cttggctttt cggttgaagg tgaattgatg cacgagttct ttattaatgg
     3901 tcaatatcgt aatgccattc gcatgtgtat attccagcat cagtatctgg cagagcacaa
     3961 aacaccgggt cagactctcc tgaagccgac cgcacaatag cattaataat aatcgatcgt
     4021 atttttgatg gtgtaaaccc gttcgacggc gggttttact ccttcatcaa caatgattag
     4081 ctgacagtcc accggattag cgtgactgtc atattcacag ctctgtttta cattaccaac
     4141 ccgttgatta ttcagtaaag taaccgctgt gtaatctaat tttttgatcg gatccgttga
     4201 tggcgtggcg ctgacagata atgttttgtc gttacttttc gtggttttac ccagcggata
     4261 accctgatca tcatagcgat attccatctg catttgtttg ctgctggctt taatcacgaa
     4321 gccattatca tcggtttccc aactcacccc ggcagaaggt aattctgcta gctggcattt
     4381 tccctgtaaa cgtactctct tctccagcgt ctcggcatca cggtaataat tggcgtccag
     4441 taccagagcg accacggtat tattttccag atccagtaat tcgagtgaat caaaacagcc
     4501 ttcttccgac aaagtcccag aaacacgttt cgtcacttca ccttgctcat ccattaatgt
     4561 ctgagtgaaa tcttttaccg gaccacgcag cggatcaaaa tcgaattcat tagagaaact
     4621 ggccatctca ggggtaaatg aaagtgttac ctctgtgcgg tcacatcctg tgaggaatat
     4681 cgcgagtaag catggtagta atttgtattt cacaacagtc accagagagt agagatgatt
     4741 ctcaatcata gtagcaaata cagtacttta cacgttaaat gctatgctta aagaagttat
     4801 cttcgcgtaa ggagcttatg atgaaactct caacctgctg tgccgcgctt ctgctcgccc
     4861 tcgcctcacc cgcggtactc gccgcgccgg gatcctgtga gcgcatacag agcgatatat
     4921 cacagcgcat tatcaataat ggcgtacccg aaagcagctt cacgttaagt attgtaccca
     4981 atgaccaggt tgatcagcct gattcccagg tcgtcggcca ttgcgctaat gatacgcata
     5041 aaattctcta tacccgcacc accagcggta acgtctctgc tcccgcgcag tctagccagg
     5101 atggcgcgcc tgccgaaccg cagtaacaca ttatcgactg aacgccggat atgacaaatc
     5161 cggcgatttg aacatacaac ataatcccac cttattactc atacccttct attgatatgg
     5221 attaataatt cttaacccaa aatgggtaaa ctccctctat tgttagcgcg ctaaatattc
     5281 aatatataaa cttttatata acgataaaga acagggagtg agttatgtcc aaaaatgaac
     5341 gaatggtggg catcagccgc agaacactcg ttaaatctac cgcgataggt tctctggcgc
     5401 tggctgcagg cggtttttct ttgccgttta ccctgcgcaa tgcagcagca gcggtacaac
     5461 aggcccgcga aaaagtggtc tggggtgcct gttccgtcaa ctgtggtagc cgctgtgcac
     5521 ttcgtctaca tgttaaagat aatgaagtga cctgggtgga aactgacaat accggcagcg
     5581 atgagtacgg caaccatcag gtacgcgcct gtttgcgcgg tcgctccatc cgccggcgta
     5641 ttaatcatcc cgatcgcttg aattacccaa tgaaacgcgt gggcaaacgc ggcgaaggca
     5701 aattcgaacg gattagctgg gatgaagccc tggatactat cgccagtagc ctgaagaaaa
     5761 ccgtcgaaca atatggcaat gaggctgtat atattcagta ctcttcgggg atcgttggcg
     5821 gcaatatgac ccgctcttcg ccatcagcct cggcggtcaa acgcctgatg aactgctacg
     5881 gcggttcact caaccagtat ggctcctaca gcactgcgca aatttcctgt gccatgccct
     5941 acacctacgg cagtaatgat ggcaacagca ccacggatat tgaaaacagc aagctggtcg
     6001 tgatgtttgg taacaacccg gcagaaaccc gcatgagcgg tggtggcatc acttatcttc
     6061 ttgaaaaagc gcgcgagaaa tcgaacgcca aaatgattgt tatcgatccg cgatataccg
     6121 atacggctgc cggtcgtgaa gacgaatggc tccctattcg cccgggcacc gatgccgcgc
     6181 tggttgcggg tattgcctgg gtattgatta acgaaaatct cgttgatcaa ccttttctcg
     6241 ataaatactg cgtcggctat gacgaaaaaa ccttacccgc agatgcaccc aaaaatggtc
     6301 actataaagc ctatattctt ggtgaaggtg acgataaaac agcgaaaacg ccgcagtggg
     6361 cttcgcaaat taccggtatc ccggaggacc gtatcatcaa actggcgcgt gaaattggca
     6421 cagcaaaacc cgcttatatc tgccagggct gggggccaca acgccaggca aacggcgaac
     6481 tgactgcacg cgctattgct atgttaccta ttttgacggg caatgtcggc atcagcggcg
     6541 gaaatagtgg cgcgcgtgaa tcgacctata ccattaccat agaacgcctg ccggtgctgg
     6601 ataatccggt caaaacgtca atctcctgct tcagctggac agatgctatc gatcatggtc
     6661 cgcaaatgac ggcaatccgc gacggcgtcc gcggcaaaga taaactggat gtgcccatta
     6721 agttcatctg gaactacgcg ggaaataccc tcgttaatca gcattctgac atcaacaaaa
     6781 cgcatgaaat tctgcaggac gaatcgaaat gcgaaatgat tgtggtcatc gaaaacttta
     6841 tgacctcatc ggcaaaatat gccgacattc tgctgccaga cctgatgacc gttgagcagg
     6901 aagatattat tcctaacgac tacgccggta acatgggata tctcattttc ctccagcctg
     6961 tcaccagcga aaaattcgaa cgcaaaccga tttactggat cctgagtgaa gtcgcgaaac
     7021 gtcttggacc tgacgtctat caaaagttca cagaaggtcg cacgcaggaa caatggttac
     7081 aacatctgta cgccaaaatg cttgccaaag atccggcgtt accgtcttac gacgaactga
     7141 aaaaaatggg tatctataag cgtaaagatc ccaatggcca ttttgtcgcc tacaaagcat
     7201 ttcgtgacga ccccgaggca aatccactta aaacgccttc cggtaagatt gaaatttatt
     7261 ccagcaggct ggcggaaatt gcccgtacct gggaactgga aaaagatgaa gtgataagcc
     7321 cattgccagt ttatgcctca acctttgaag gctggaactc ccctgaacgt agaaccttcc
     7381 cactgcaact gtttggtttc cattacaaat cccgtactca ctcgacctac ggcaatattg
     7441 atctcctgaa ggctgcctgc cgtcaggagg tgtggatcaa ccctatagat gcgcagaaac
     7501 gtgggattgc caacggcgat atggtgcggg tgtttaacca tcgtggcgaa gttcggctac
     7561 cagccaaagt aacaccacgt attctccctg gagttagcgc tatgggccag ggagcctggc
     7621 acgaggccaa tatgtctggc aataaaatcg accatggcgg ctgtgtgaat acgctaacca
     7681 ctctgcgccc ttcaccactg gcgaagggaa acccgcagca cactaatctg gtcgagatcg
     7741 aaaaaatata acccacgaca accataaatt ctggcatgac attttgtttg aaaagcaata
     7801 agtgagtaat gatgaaaatc cataccacag aggcgctcat gaaggctgaa atcagccgta
     7861 gaagtctgat gaaaacctcc gcacttggca gtcttgcgct ggcaagcagt gctttcactc
     7921 tgccattttc ccaaatggtc cgggcggcag aggctccggt agaagagaaa gcggtctgga
     7981 gttcctgcac cgttaactgc gggagccgct gtctgttacg tttgcatgtg aaagatgaca
     8041 ccgtgtactg ggtggagtct gatacgacag gtgacgacgt ctacggtaat catcaggttc
     8101 gagcgtgttt acgcgggcgc tctatccgcc gacggatgaa tcatcctgat aggttgaaat
     8161 atcccatgaa gcgcgtcggc aagcgcggtg aaggtaaatt tgaacggata agttgggacg
     8221 aagccctgga taccatcagt gataatcttc ggcggatcct gaaagattac ggcaatgagg
     8281 ctgtacatgt cctgtacgga acaggcgtag atggcggaaa catcaccaac tcaaacgtcc
     8341 cgtaccgtct gatgaactct tgcggtggtt ttctcagtcg ctatggcagc tacagtaccg
     8401 cacagatcag tgccgcaatg agttatatgt tcggtgccaa tgatggcaac agcccggatg
     8461 atatcgccaa tacgaaactg gtcgttatgt tcggaaataa cccggcagaa acgcggatga
     8521 gcggcggtgg tgtcacttac tacgtcgagc aagcccgcga acgttcaaac gcacgcatga
     8581 tcgtcatcga tccacgttat aacgacactg ctgccgggcg tgaagatgaa tggctgccca
     8641 ttcgccctgg caccgatggc gcactggcct gtgcgattgc ctgggtactg attactgaaa
     8701 acatggtcga tcagccattt ctcgacaaat attgtgttgg ttacgatgaa aaaacgctgc
     8761 ccgccaacgc accacgtaac gcgcattata aagcctatat tctgggcgaa gggcctgacg
     8821 gcatagctaa aacgccggaa tgggcagcaa aaatcaccag catcccggca gaaaaaatta
     8881 tccagttggc acgagagatc ggttcagcaa aacctgctta tatttgtcag ggttgggggc
     8941 cacaacgaca ttccaacggc gagcaaacat cccgcgctat tgccatgctt tccgttctca
     9001 ccggcaacgt cggcataaac ggcggcaact caggcgtacg cgaaggtagc tgggatctgg
     9061 gggtagaatg gttcccgatg ctcgagaatc ctgttaaaac gcagatttcc gtctttacat
     9121 ggacagatgc catcgaccat ggtacggaaa tgaccgcgac ccgtgatggt gttcgtggaa
     9181 aagaaaaact ggatgtcccc atcaagtttt tatggtgcta cgccagtaac acattgatca
     9241 atcaacatgg cgacatcaat cacacccatg aggtgcttca ggatgacagc aagtgcgaga
     9301 tgattgttgg cattgaccac ttcatgacgg cctcggctaa gtattgcgat atcctgttgc
     9361 ccgacctgat gccaacagag caagaagacc ttatctctca tgaatctgca gggaatatgg
     9421 gctatgtgat cctcgcccaa cccgcaacct cagcaaaatt tgaacgcaaa cccatctact
     9481 ggatgctgag tgaagtcgcc aaacgcttag gaccagacgt ttatcaaacc tttactgaag
     9541 gtcgcagtca gcatgaatgg atcaaatatc tccatgcgaa aacgaaggaa cgtaaccctg
     9601 agatgcccga ctacgaggag atgaaaacga ccgggatctt taagaaaaaa tgcccggaag
     9661 aacactacgt cgctttccgc gcattccgtg aagatccaca ggcaaacccg ttgaaaacac
     9721 cttcggggaa aatcgaaatt tattctgaac gactggcgaa gattgcagat acctgggaat
     9781 tgaaaaaaga tgaaattatt catccccttc ctgcgtatac cccaggtttt gatggctggg
     9841 acgatcccct gcggaaaacc tatccactgc agttaacggg cttccattac aaagcgcgta
     9901 cccactccag ctacggcaat attgatgtgt tacagcaggc ctgcccacaa gaggtgtgga
     9961 tcaaccccat tgatgctcag gcacgcggta tccgtcatgg cgataccgtg cgggtattta
    10021 acaataatgg agaaatgctg attgccgcaa aagtgactcc gcgtattctg cctggcgtta
    10081 ccgccatcgg gcaaggtgcg tggcttaaag cggatatgtt tggtgaccgg gtcgatcacg
    10141 gcggcagtat caatattctg acctctcacc gcccttcacc gctggcaaag ggaaacccgt
    10201 cgcacagcaa tcttgtccag atcgaaaagg tttaaggagt agcccatgac cacacaatat
    10261 ggatttttta tcgattccag ccgctgtact ggctgtaaaa cctgcgaact ggcgtgcaaa
    10321 gattttaaag atcttggccc ggaagtcagt ttccgccgta tttatgaata cgctggcggc
    10381 gactggcagg aagataatgg cgtctggcac cagaacgtgt tcgcttatta tctctccatc
    10441 tcctgtaacc attgcgatga ccccgcatgt acaaaagtct gccccagcgg cgcaatgcat
    10501 aagcgtgaag atggctttgt ggtggttgat gaagatgttt gtatcggctg ccgctactgc
    10561 cacatggctt gtccgtacgg cgcgccacag tacaatgctg aaaaagggca catgacgaag
    10621 tgcgatggtt gttattcgcg cgtcgccgag gggaaacaac ccatatgtgt cgaatcctgc
    10681 ccgctgcgtg cacttgagtt cggtccaatt gaagagctgc gccagaagca cggcactctt
    10741 gctgccgtcg cgccactgcc gcgcgcgcat ttcacaaaac ccaatatcgt tatcaaacct
    10801 aacgccaaca gccgcccgac cggcgatacc actggttatc tggctaatcc ggaggaagtg
    10861 taaaatggga aatggatggc atgagtggcc actggttatc tttaccgtat tgggtcaatg
    10921 cgtagtaggc gcgctgattg ttagcggaat tggctggttc gccgccaaaa atgacgcaga
    10981 ccgtcagcgt attgtccgtg gcatgttttt cctctggctg ttgatgggcg tcgggtttat
    11041 tgcctctgtc atgcacctgg gatcgccact gcgggcgttt aactcgctga atcgaatcgg
    11101 agcttctggt ctgagtaacg agattgctgc cggttccata ttttttgccg ttggcggatt
    11161 atggtggctg gtggcagtca tcggtaaaat gccgcaagcg ttggggaaac tctggttact
    11221 tttcagcatg gcgctcggcg tcattttcgt ctggatgatg acctgcgtgt atcaaatcga
    11281 caccgtgcca acctggcata acggttacac tacgctggct ttcttcctga cggtattgtt
    11341 gagcggtcca atacttgctg ccgcaattct gcgggcagct cgcgttacat ttaataccac
    11401 accatttgcc atcattagcg ttctggcgct gatcgcttgt gccggggtga ttgtgctgca
    11461 aggtttgtct ctggcgtcta ttcactcatc cgtgcaacaa gccagcgcac tggtaccaga
    11521 ttacgcctcc ttacaggtct ggcgtgtggt attgttatgc gcaggtcttg gatgctggct
    11581 ttgcccgctc attcgtcgcc gtgaacctca cgttgccgga cttattctgg ggctaatcct
    11641 catacttggc ggtgagatga tcgggcgtgt gctcttttat ggcctgcaca tgacagtagg
    11701 aatggctatt gcaggttaac aaattggtgc ggggcaaccc gcacatttca ggatgttagg
    11761 aatgacccat ttttcacagc aagataattt ttctgtcgcg gcgcgcgtgt tgggcgcgct
    11821 gttttattac gctccagaga gtgcggaagc cgcacctctg gttgcggtac tcaccagtga
    11881 cggctgggaa actcagtggc ctctaccaga agcgtcatta gcgccgctgg tgacggcttt
    11941 tcagacacag tgtgaagaga ctcacgccca ggcctggcag cgtttgtttg tcggcccgtg
    12001 ggcactgccg tctccgccgt gggggtcggt ctggctggat cgcgaatctg tgctgtttgg
    12061 cgattcaaca ttggcacttc gtcagtggat gcgcgagaaa ggcattcagt ttgaaatgaa
    12121 gcaaaacgaa ccggaagatc attttggttc actgctgttg atggctgcgt ggttggcgga
    12181 gaatggtcgc cagacagaat gcgaagaatt gctggcatgg cacctttttc cgtggtcaac
    12241 acgttttctt gatgttttta tcgaaaaagc agaacaccct ttctaccgtg cactgggtga
    12301 actggctcgc ttaacgctgg cgcaatggca atcacaactg ttaattcctg tcgcggttaa
    12361 accgctgttt c
//
LOCUS       DAPHKZ010000134        12263 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.134, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000134 DAPHKZ010000000
VERSION     DAPHKZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12263
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.134"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(57..965)
                     /gene="melR"
                     /locus_tag="RH288_003832"
     CDS             complement(57..965)
                     /gene="melR"
                     /locus_tag="RH288_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HDV4032843.1"
                     /translation="MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWH
                     GQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACTPHQLTDTGTCQSMAIFNLPMHL
                     FLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
                     LKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVK
                     LNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYS
                     TFGKYVGMSPQQYRKLSQQRRQTFPG"
     gene            1248..2603
                     /gene="melA"
                     /locus_tag="RH288_003833"
     CDS             1248..2603
                     /gene="melA"
                     /locus_tag="RH288_003833"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDV4032844.1"
                     /translation="MMSAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPT
                     RLEESHIVVRKLMDSAGASGKITCHTQQKEALEDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGS
                     YVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEEYKKASRIDIKPSREYASTIMNA
                     IWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKVGTLPSHLAALMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLH
                     R"
     gene            2706..4127
                     /gene="melB"
                     /locus_tag="RH288_003834"
     CDS             2706..4127
                     /gene="melB"
                     /locus_tag="RH288_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418544.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="melibiose:sodium transporter MelB"
                     /protein_id="HDV4032845.1"
                     /translation="MSISMTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLV
                     GTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLANSVILFLLFSAHLFEG
                     TTQIVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPYPRFFASLAGFVTA
                     GVTLPFVNYVGGGDRGFGFQMFTLVLIAFFIVSTIITLRNVHEVFSSDNQPSAEGSHL
                     TLKAIVALIYKNDQLSCLLGMALAYNVASNIITGFAIYYFSYVIGDADLFPYYLSYAG
                     AANLVTLVFFPRLVKSLSRRILWAGASILPVLSCGVLLLMALMSYHNVVLIVIAGILL
                     NVGTALFWVLQVIMVADIVDYGEYKLHVRCESIAYSVQTMVVKGGSAFAAFFIAVVLG
                     MIGYVPNVEQSTQALLGMQFIMIALPTLFFMVTLILYFRFYRLNGDTLRRIQIHLLDK
                     YRKVPPEPVHADIPVGAVSDVKA"
     gene            complement(4266..4895)
                     /locus_tag="RH288_003835"
     CDS             complement(4266..4895)
                     /locus_tag="RH288_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HDV4032846.1"
                     /translation="MTRTLKPLILNTSALTLTLILIYTGISAHDKLTWLMEVTPVIIV
                     VQLLLATARRYPLTPLLYTLIFLHAIILMVGGQYTYAKVPVGFEVQEWLGLSRNPYDK
                     LGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWWAALAMGQ
                     GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITG"
     gene            complement(5018..6664)
                     /gene="fumB"
                     /locus_tag="RH288_003836"
     CDS             complement(5018..6664)
                     /gene="fumB"
                     /locus_tag="RH288_003836"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HDV4032847.1"
                     /translation="MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEP
                     EALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDVQLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYQVSTRLSLTGTIIVG
                     RDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK"
     gene            complement(6742..8082)
                     /gene="dcuB"
                     /locus_tag="RH288_003837"
     CDS             complement(6742..8082)
                     /gene="dcuB"
                     /locus_tag="RH288_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HDV4032848.1"
                     /translation="MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREY
                     VYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            complement(8653..9372)
                     /gene="dcuR"
                     /locus_tag="RH288_003838"
     CDS             complement(8653..9372)
                     /gene="dcuR"
                     /locus_tag="RH288_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HDV4032849.1"
                     /translation="MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIF
                     NSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
                     PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRIQAEHYSLLKQYCQ"
     gene            complement(9369..11000)
                     /gene="dcuS"
                     /locus_tag="RH288_003839"
     CDS             complement(9369..11000)
                     /gene="dcuS"
                     /locus_tag="RH288_003839"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HDV4032850.1"
                     /translation="MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQI
                     SDMTRDGLANKALAVARTLADSPEIRQGLQKKPQESGIQAIAEAVRKRNDLLFIVVTD
                     MQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQI
                     GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQV
                     VDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRL
                     DGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKI
                     KSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEAL
                     GPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVK
                     QQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR"
     gene            11181..11411
                     /locus_tag="RH288_003840"
     CDS             11181..11411
                     /locus_tag="RH288_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDV4032851.1"
                     /translation="MDQALLDGGYRCYTGEKIDVYFNTAICQHSGNCVRGNGKLFNLK
                     RKPWIMPDEVDVATVVKVIDTCPSGALKYRHK"
     gene            11423..11695
                     /locus_tag="RH288_003841"
     CDS             11423..11695
                     /locus_tag="RH288_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV4032852.1"
                     /translation="MEIREGHNKFYINDKQGKQIAEIVFVPTGENLAIIEHTDVDESL
                     KGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKTREYDDIRS"
     gene            11922..12218
                     /gene="ghoS"
                     /locus_tag="RH288_003842"
     CDS             11922..12218
                     /gene="ghoS"
                     /locus_tag="RH288_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HDV4032853.1"
                     /translation="MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEY
                     GIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK"
BASE COUNT         2991 a         2909 c         3147 g         3216 t
ORIGIN      
        1 ttcactgctt attatcgacg gctaaactat ttttttggct gatactgata tcgtctttag
       61 ccgggaaacg tctggcggcg ctgttggcta agtttgcggt attgttgcgg cgacatgccg
      121 acatatttgc cgaacgtgct gtaaaaacga ctacttgaac gaaagcctgc cgtcagggca
      181 atatcgagaa tacttttatc ggtatcgctc agtaacgcgc gaacgtggtt gatgcgcatc
      241 gcggtaatgt actgtttcat cgtcaattgc atgacccgct ggaatatccc cattgcatag
      301 ttggcgttaa gtttgacgtg ctcagccaca tcgttgatgg tcagcgcctg atcatagttt
      361 tcggcaataa agcccagcat ctggctaaca taaaattgcg catggcgcga gacgctgttt
      421 ttgtgtgtgc gcgaggtttt attgaccaga atcggttccc agccagagag gctaaatcgc
      481 ttgagcatca ggccaatttc atcaatggcg agctggcgaa tttgctcgtt cggactgttt
      541 aattcctgct gccagcggcg cacttcaaac gggctaagtt gctgtgtggc cagtgatttg
      601 atcaccatgc cgtgagtgac gtggttaatc aggtctttat ccagcggcca ggagagaaac
      661 agatgcatcg gcagattaaa aatcgccatg ctctgacagg ttccggtatc tgttagttgg
      721 tgcggtgtac aggcccagaa cagcgtgata tgaccctgat tgatattcac tttttcattg
      781 ttgatcaggt attccacatc gccatcgaaa ggcacattca cttcgacctg accatgccag
      841 tggctggtgg gcatgatatg cggtgcgcga aactcaatct ccatccgctg gtattccgaa
      901 tacagcgaca gcgggctgcg ggtctgtttt tcgtcgctgc tgcacataaa cgtatctgta
      961 ttcatggatg gctctctttc ctggaatatc agaattatgg caggagtgag ggaggatgac
     1021 tgcgagtggg agcacggttt tcaccctctt cccagagggg cgaggggact ctccgagtat
     1081 catgaggccg aaaactctgc ttttcaggta atttattccc ataaactcag atttactgct
     1141 gcttcacgca ggatctgagt ttatgggaat gctcaacctg gaagccggag gttttctgca
     1201 gattcgcctg ccatgatgaa gttattcaag caagccagga gatctgcatg atgtctgcac
     1261 ccaaaattac atttatcggc gctggttcga cgattttcgt taaaaatatt cttggtgatg
     1321 tgttccatcg cgaggcgctg aaaacggcgc atattgccct gatggacatt gaccccaccc
     1381 gcctggaaga gtcgcatatt gtggtgcgta agctgatgga ttcagcaggg gccagcggca
     1441 aaatcacctg ccacacccaa cagaaagaag ccttagagga tgccgatttt gtcgtggtgg
     1501 catttcagat tggcggttat gaaccttgca cggtgactga tttcgaggtc tgtaagcggc
     1561 atggtctgga acaaaccatt gccgatacgt tggggccggg cggtattatg cgcgcgctac
     1621 gtaccattcc gcatctgtgg caaatttgcg aggacatgac ggaagtctgc cccgatgcca
     1681 ccatgctcaa ctatgttaac ccaatggcga tgaatacctg ggcgatgtat gcccgctatc
     1741 cgcatatcaa acaggtcggg ctgtgccatt cggtgcaggg aacggcggaa gagttggcgc
     1801 gtgacctcaa tatcgaccca gctacgctgc gttaccgttg cgcaggtatc aaccatatgg
     1861 cgttttacct ggagctggag cgcaaaaccg ccgacggcag ttatgtgaat ctctacccgg
     1921 aactgctggc ggcttatgaa gcagggcagg caccgaagcc gaatattcat ggcaatactc
     1981 gctgccagaa tattgtgcgc tacgaaatgt tcaaaaagct gggctatttc gtcacggaat
     2041 cgtcagaaca ttttgctgag tacacaccgt ggtttattaa gccaggtcgt gaggatttga
     2101 ttgagcgtta taaagtaccg ctggatgagt acccgaaacg ctgcgtcgag cagctggcga
     2161 actggcataa agagctggag gagtataaaa aagcctcccg gattgatatt aaaccgtcac
     2221 gggaatatgc cagcacaatc atgaacgcta tctggactgg cgagccgagt gtgatttacg
     2281 gcaacgtccg taacgatggt ttgattgata acctgccaca aggatgttgc gtggaagtag
     2341 cctgtctggt tgatgctaat ggcattcagc cgaccaaagt cggtacgcta ccttcgcatc
     2401 tggccgccct gatgcaaacc aacatcaacg tacagacgct gctgaccgaa gctattctta
     2461 cggaaaatcg cgaccgtgtt taccacgccg cgatgatgga cccgcatact gccgccgtgc
     2521 tgggcattga cgaaatatat gctcttgttg acgacctgat tgccgcccac ggcgactggc
     2581 tgccaggctg gttgcaccgt taaaacgcga ctaaacgcta ctgcgccggg ggatttattc
     2641 cggcgcacac ctctgacgat accaataaca gaaggcgggc gttggtaaca gcgacccgat
     2701 accctatgag catttcaatg actacaaaac tcagttatgg atttggagcg ttcgggaagg
     2761 attttgcgat cggcattgtg tatatgtacc tcatgtatta ctacaccgat gtcgtcgggc
     2821 tgtctgtggg tttggtcggt actttgtttc tggtggcgag gatctgggat gctattaacg
     2881 atccgattat gggatggatt gtaaatgcta cgcgatcgcg atggggtaag ttcaaaccct
     2941 ggatcctgat cggtacgttg gcaaactctg taatcttatt tctcctcttt agtgcgcatc
     3001 tgtttgaagg tactactcag attgtctttg tttgcgtgac ctacatcctc tggggcatga
     3061 cttacaccat tatggatatt cccttctggt cgctggttcc aaccatcacg ctcgataaac
     3121 gtgagcgcga acaactggtt ccttatccgc gtttttttgc cagtctggca ggctttgtta
     3181 cggcaggtgt gacgctacca tttgttaatt atgtcggcgg tggcgatcgg ggatttggct
     3241 ttcagatgtt cactctggta ctgatcgcct tttttattgt ttcaaccatc atcactctgc
     3301 gcaatgtgca tgaagtcttt tcgtcagaca atcaaccgtc tgctgaagga agccatctga
     3361 cacttaaagc catcgttgcg ctaatttata aaaacgatca gctttcatgc ctcttgggta
     3421 tggctcttgc ttataatgta gccagcaaca ttattaccgg ctttgctatc tattatttct
     3481 catatgttat cggtgatgcg gatttgttcc cctattatct gtcgtatgcg ggagctgcta
     3541 acctggtgac gttagtattc ttcccacgct tagttaaatc attatcccga cgcattttat
     3601 gggccggagc atctattctt ccggtgttaa gctgtggtgt tctcctgtta atggcattaa
     3661 tgagctatca caacgtcgtc ctcattgtga ttgcgggtat tttgctgaat gtgggaacgg
     3721 cgcttttctg ggtattacag gtcatcatgg tggcagatat cgttgattac ggtgaatata
     3781 aactgcacgt acgctgtgaa agtatcgctt actccgtgca gactatggtg gtgaagggcg
     3841 gttcagcctt tgcggctttt ttcattgcgg ttgtgttagg gatgattggc tatgtaccga
     3901 atgttgaaca gtctacgcaa gccctattag gtatgcagtt tattatgatt gctctaccaa
     3961 ctctgttttt catggtaacg ctgattctct acttccgttt ctatcgcctc aatggtgaca
     4021 cgctgcgcag gatccagatc catctgctgg ataaatatcg caaagtaccg cccgagcctg
     4081 ttcatgctga tattccggtc ggtgcagtga gtgatgtgaa agcctgacgt ggacaatagc
     4141 taacgaaaat ggcctgatgc gatatgttta tcaggccacg tcttaatgta atgctttgga
     4201 tttgcaaatt ttgtagaccg gataaggaat tcacgccgca tccggcatca acaaagcgca
     4261 agttgttatc cggttatcaa gccaaagcgc cgtagctggc ggcaatgaaa gcgagcgagg
     4321 aatatcaccg tcgttaatgc gccaagcagc gcgcagaaca tatcggattg cgtgtcccac
     4381 tggtcgccct gggtgccgag aaaatcatcc gctccctgac ccattgccag cgctgcccac
     4441 cactcgatta attcatacat cgcgcttatc gccagcgcca cgcagcagac caggaacgcc
     4501 accattttac gtccgcgcac gtacatcccg cgaacgagaa tttctcgtgc caccagtgca
     4561 ggcaccagcc cctggaaaaa gtgccccagc ttgtcatacg gattacgact caaccccagc
     4621 cattcctgca cctcaaaacc aacggggact ttcgcgtagg tgtattgtcc gccgaccatc
     4681 aggatgatgg cgtgaaggaa aatgagcgta tagagcagcg gcgttaacgg ataacgtctg
     4741 gcggtggcaa gcagtagctg cacgacaata atcaccggtg tcacttccat cagccaggtg
     4801 agtttgtcat gggccgaaat gccggtataa atcaggatta acgttagcgt cagtgcgctg
     4861 gtgttaagaa ttaacggctt gagtgtgcgg gtcatggtga gttcgcaaat cagggaaaat
     4921 actgactatt caccagcaag cgtgaaatta caatcgcaaa agaggtggcc cagggggatc
     4981 acctggcagc atgctgccag gcgctgggcc gaagaggtta cttagtgcag ttcgcgcact
     5041 gtttgttgac gatttgctgg aagaagtcgt tacctttgtc atcgaccagg ataaacgccg
     5101 ggaaatcttc tacttcgatt ttccagatag cttccatacc cagctccgga taagcgacgc
     5161 actccagatg cttgatgctc tgctgcgcca gtaccgccgc cggaccgccg atgctaccga
     5221 ggtagaagcc gccgtgttta tgacacgcgt cggtaacctg ctgactgcgg ttacctttcg
     5281 ccagcatgat catgctgccg ccgtgggatt gcagcagatc cacgtaggag tccatacggc
     5341 ctgcggtggt tgggccaagt gaacctgatg gataaccggc aggggttttc gccggacccg
     5401 cgtagtagat cgggtgatct ttgatgtact gcggaagttc tttaccggcg tcaatcagct
     5461 ctttcagctt ggcgtgtgca atatctcggc ccacgataat ggtgccggtg agcgacaaac
     5521 gagtggatac ctggtattgc gaaagctggg cgaggatctc tttcatcggg cggttaaggt
     5581 caactttcac cgcttcgcct tcaccggcct ggcgcagttc ttgtggaatg tactggcctg
     5641 ggttgtgttc cagtttttcg atccagatac cttcgcggtt gattttcgct ttaatgttac
     5701 ggtcagcgga gcaggagacg cccatgccga ccgggcagga tgcgccgtga cgtggcagac
     5761 ggataacgcg aatgtcgtgc gcgaagtatt taccgccaaa ctgcgcgcca agaccgagtt
     5821 tctgggcctc ttccagcagt tcctgttcca gctggacatc gcggaacgcc tgaccatgtt
     5881 cgttcccttc cgtcggcagt tcatcgtaat agtgagcgct tgctaacttg acggttttca
     5941 ggttggtttc cgcagacgta ccgccaatca caaacgcgat atggtacggc gggcaggctg
     6001 cagtaccgag ggtacgcatt ttctcgacga ggaagttttt cagtttgccg ggagtcagca
     6061 gggctttggt ttcctggtag agatacgttt tgttggcaga gccgccgcct ttcgcaacgc
     6121 aaaggaattt gtactcatcg ccatctaccg cgtacaggtc gatttgcgca ggcaggttag
     6181 tgccggtgtt gacctctttg tacatgtcca gcgccgcatt ctgtgaatag cgcaggttat
     6241 cttcgatata ggtgttatag acgcctttcg acagcgtttc ttcatcaccg ccgccggtcc
     6301 acacgcgctg gcctttttta ccgacgatga tcgcggtgcc ggtatcctgg caggtcggca
     6361 gcacgccttt ggcggcgatt tcggagtttc ttaagaattg cagcgccacg tacttgtcgt
     6421 tttcgctggc ttctggatcg tgaagaatag ccgcaacctg tttctggtgt gccgggcgga
     6481 gcataaaaga agcgtcgtga aaggcttgct gcgccagcag ggtcagggct tctggttcca
     6541 ctttcaggat ggtttcgccg tcgaagtcgg caacgctaac gtaatcggaa gtgagtagat
     6601 agtattcggt attgtctttc cccatcggga aaggtgcctg gtagataaag ggtttgtttg
     6661 acatagcttc cagcctgtaa ctctgtattt gttattcgaa aatggcgtgc cgcgtagtca
     6721 cgggcggcac gcaaagtgca tttataagaa cccgtacatc gcggcgaaga tccagccgaa
     6781 gacgcacgat acgctcacac caatcaaccc cggcagaata aagctgtggt tgatgacgaa
     6841 gcgaccgatg tgggtggtgc cggaacggtc aaactgaatc gctgccagat cgctcggata
     6901 agtcggcagg atgtaataac cgtagcaagc cggtgctgaa gccacgatgt atgccggatc
     6961 aacgccgatc gccagcgcga ccggaacaat cgccgccagc gccgcagcct gagagtttac
     7021 aaacttggaa accagcagca gaacaatggc ataggcccac ggatactctt tcaccatttc
     7081 acccagtacg ccctgaattt cagacatatg cgcaccgaac atggtttctg ccatccatgc
     7141 gataccgtac accgccacga tggcgatcat accggaacgg aagacttcgt tttttgagat
     7201 agacgcggga ttggttttgg tcaggataat aatcagcgcc ccggtcagca gcataaacat
     7261 ctgaataacc agtaccatcg acagcggttt gccgccgaag gatggacgca ggtccgaatc
     7321 agcaccaaga agggcgacta cagcgattgc cccgaggaaa atccacattg ccagccagtt
     7381 gcttttcggc agttttttat ccagcagcgt cgcggtatca ccgtaaacat actcacggtt
     7441 ttccggtacg gagatgaatt tctggaactc ttcgtcttta tccagatctt taccgcggaa
     7501 ccagctgaag ataccgatcg ccaggatacc gattaacgtc gatggaatgg tgattgccag
     7561 cagatcgagg aactcaagat ggcgaccatc aaaggtgaca ttacccagca tcgcaaccag
     7621 agacacgacc gcaaccgaca ccggactggc gataatcccc atctgtgcac cgatagaact
     7681 tgccgccatc ggacgttccg gacggatgtt gttcttaatg gcgacgtcgt agatgatcgg
     7741 cagaatggtg taaaccacat gacccgtacc gcaaagaatg gtcagtgtac aggtcacaaa
     7801 cggcgcgaca attgagacat atttcgggtt gcggcgcagc agcttctcgg caatttgcag
     7861 catgacatca agaccgcccg aagcttgcaa ggtcgccgat gccgccacca ccgcaatgat
     7921 aaccagcatg acatcaactg gtggtttacc tggctgaagg tggaagacga agaccagaat
     7981 gaccagaccg ataccgccta ataaacccag cgcgatacca ccctttctgg caccataaaa
     8041 cagacatatc agtattatga taagttggat agtaaataac atgtgtgaac cctcgcgata
     8101 atcctattta aatttttgct gaatagatca cagtcacgtt ctgttttgta tgaactgttt
     8161 tcagagcctg actaaatatc cgtttggtcg ttaccggctt tagcaaatac ctcacagtga
     8221 atattggctg attaaagcag cggcaaattt atgcactgtg ataagcggct ttttcagaga
     8281 gaaagactct ctggcgatgg gtttatagtt tgtactgcgc agatgttaat gttttgtttg
     8341 ctgttatctt attgatattt atcggtctat tttttgttct cagggcagat gtcattaggt
     8401 ttatagatta atctgatcta cccatttgtg ggtaaaaata cacataatgc gggtgacata
     8461 atagttaatt aacttttgtt agcgttttga aattaaaaac accgttcacc tgaagagata
     8521 ttaattttta gcgatgatgg agggataatt atatttgatc tggcacaagt tttactgatg
     8581 aaggatgtaa cttgtgccag gggtattttg cattacggta ataattatta cttacagata
     8641 accagcgatc cgttattggc aatattgttt cagtagtgag tagtgttctg cctgaatacg
     8701 gtaacggtaa actggacgcc ccgtgacgcc ataatggata ctggtgaaca agatgtggca
     8761 gttgaccagc cagatgaggt atttacggca ggaaacacgc gaaatgttaa cctcgttggc
     8821 tagctcgtcg gttgaaaatt catagtcctg atgcgcgtca atccactggc acagtgtgcg
     8881 taacgtctgc ggcgttaagc cttttggcaa gcgacgagga tcctgttcgt tggagctgct
     8941 gccgtggatt agctgatcaa gctcggcctg gtcataatac tgatgttttt ccagcgccat
     9001 tttcttttgc cgccagccgg tgagcgcctc ttcaaagcgg gaagcctgga agggtttgat
     9061 caggtaatcc acgacaccgt aatgcagcga atctttaatg gttgccgcat cggctgcgga
     9121 ggagatgaca atcacatcac ttttgcaacg cgcgttatgc aggacaggca gtaaatcgag
     9181 cccgttctct ttttgcatat agatatcgag caatatcagg tcgataggcg tatcgctatt
     9241 gaagataatc tctttggctt tctccagcgt cgaggctgtt ccacagcatt gaaagcctgg
     9301 gatttgtgct acgtatcggc gattcagctc cgcgaccatt gcgtcgtcat cgataattaa
     9361 tacattgatc atctgttcga cctctccccg tcccagggta tctggacaaa aaattgtgtg
     9421 aaaatcccgg gttccgattc cacggcgatg ctgccgccga gattttctac ctgttgtttg
     9481 acaagtgcta aaccgacgcc tcgctcgctt ccttttgtcg agacaccttt gtcaaaaatg
     9541 tgatcgattt tatcgggtgc gatccccggt ccatcatcat taacttcaca gtgcagccag
     9601 ccgtgacggt agtgcaatgt tacgctaatt tcgcctccgg gttccggccc taatgcctcc
     9661 agcgcgtttt ctatcagatt tcccaacgtg gtaatcagcg tcgcgacctg gtcctcactg
     9721 ccgctgtctg gcagctggct ttcactgttt aaaatcagcg tatggcctaa atcggtcgcg
     9781 cggttaatct tgctgattaa aaaaccagcg ataaccggag atttgatctt acccagcaga
     9841 gagccaatct cttcctgata gttattggct gttttgagaa tgtaatcttc caactgctta
     9901 taactcttca gatgcaataa tccgagaatc acatgcaatt tattcataaa ttcgtgggat
     9961 cgttcacgaa gtgcgtcagc atagttgacc agaccgtcga gtcgctgcat cagtttacgt
    10021 acttcagttt tgtccctgaa ggttgaaatg gcaccgatga taacgccatt actgcgcacc
    10081 ggaacggtgt tgatcagtaa tagccggtct ttaatcgtaa tctcttcgtc gcggcgcggg
    10141 gtaccgtcgc gtaacacttc cgagacatct accacctgtg accatgagtg gcttagcgtc
    10201 gacagtttct catcgtcctg cgacttacgg taattcagca attcttgtgc ggcatcgttg
    10261 atcagcgtga cctcgccgcg atcgtccacg gcaacgacgc cttctttgat agactgcaac
    10321 atggcctggc gttgctcaaa cagcgtggag atttcgtagg gttccaggcc gaaaaggatt
    10381 tttttcagta ccttaaccag aatgcaggtg ccaatcagtc cgaccagcat gccaaataat
    10441 accgaccaga taatgctcca gcgactgtca ttgatctgtt gggtcacacg gcttaactca
    10501 aggccgatcg ccaccacgcc aatttgttta tgattttcat cgtagatggg ggtaaatacg
    10561 cgtaaagcct gcgccagaaa accgcgattg atagcgacat tttcttcgcc attcagcgct
    10621 ttaaggatgt catcaccttt aaatggctga ccaatacgct gggcttcagg atgcgagtag
    10681 cgaagacttt gcatatcggt aacgacaata aacagcagat cgttgcgttt gcgtacggct
    10741 tccgcgatgg cctggatgcc actctcctgc ggttttttct gcaagccctg acggatttcc
    10801 ggcgagtcgg cgagggtacg cgccactgcc agtgccttgt tggctagccc atctcgcgtc
    10861 atatcactga tttgcgagaa gtaaatcaga tgcaccacca atagcaccga gaacagtacc
    10921 gcactgacca ttaagatcac tgtggtactc aatttcatcg gacgtttgcg taacatgcgg
    10981 tagggcaatg aatgtctcat cagcttcctt gtgtgacaaa tttcttaagc attatctctg
    11041 atgaggcggg taattcaaag ggagtaagaa tgattggcta tataggggaa gagactctgg
    11101 caacggaaac tgccagtgct gtatgaagat tccggggcta tgcttatagc gataatcata
    11161 ctgatgagag agggaaggtc atggatcagg cgctactgga cgggggttat cgctgttata
    11221 ccggcgaaaa gatcgatgtc tatttcaaca ctgcgatatg tcagcattct ggcaattgcg
    11281 tacgtggcaa cggcaagtta tttaatctca aacgaaagcc gtggatcatg ccggatgaag
    11341 tcgacgtcgc cactgtggtt aaagtgattg atacgtgccc gagcggcgcg ctgaaatacc
    11401 gtcataaata agcgagggta aaatggaaat acgcgaaggc cacaataaat tttacattaa
    11461 tgacaaacaa ggcaagcaaa tcgctgaaat tgtctttgtg ccgaccggag agaatttagc
    11521 gattatcgaa cataccgatg tcgatgaaag cctgaaaggg caagggattg gtaaacagct
    11581 ggttgcgaaa gtcgtggaaa aaatgcgtcg ggaaaaacga aaaattatcc cattatgccc
    11641 atttgcgaaa catgaatttg ataaaacgcg ggagtatgat gatattcgca gttgatggga
    11701 gagtacagag tcacgatatt tttcattctc tccgcgatgt gatgcaggag agcatctgaa
    11761 gggtaggggg atgcacaaag aatgggcaga gagcgcgttt ttttgtccca agtcatcccc
    11821 tttactgagc aaaaaaaaga atatctccta tatgagaatc atcaatcggg gttaataagt
    11881 tttgcgtccc cagagcgttt aatattgata ggagtcatat tatggaaggt aaaaacaagt
    11941 tcaatactta tgttgtttct tttgattatc catcatctta ttcctcagtg ttcttaagat
    12001 taagatcatt gatgtatgat atgaatttct cctctatcgt ggctgatgaa tatgggatac
    12061 cacgacaatt gaatgaaaac tccttcgcaa taacgacatc gttagccgca agtgaaatcg
    12121 aagatttaat caggctcaaa tgcttagact taccggatat tgattttgac ctcaacatta
    12181 tgacagttga tgactatttc cgtcagtttt acaagtagcc aggaaggata agaagaacat
    12241 aaaaaatggc actattctct aaa
//
LOCUS       DAPHKZ010000135        12148 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.135, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000135 DAPHKZ010000000
VERSION     DAPHKZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12148
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.135"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(360..1673)
                     /locus_tag="RH288_003843"
     CDS             complement(360..1673)
                     /locus_tag="RH288_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001481272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HDV4032854.1"
                     /translation="MIKETVTMSHKELHRLQIIQEQAAARIGISIRQVKRLVQRYRNE
                     GPSGLVSHRRGKRPNNSFSTEFRATVISLLKGRYADFGPTFACEKLREIHGLSLSVET
                     LRKWMIEEGLWRERRRKIARIYQRRMRRPSYGELIQIDGSPHDWFENRGPRCTLIVFI
                     DDATSALMALRFVPAETTRAYMETLRGYLNDHGVPLALYSDRHSIFRVNNPEREGELT
                     QFTRAIKTLGIEPIHANSPQAKGRVERANQTLQDRLVKEMRLQNISDIETANAWLPTF
                     IEAYNNRFATSPRTTDNAHLDVHHSEEELGYIFSLQAKRVLSKNLTFQYKSSAFQVRS
                     EGRGYRLRHSVVTVCENFDGEINVLYDGKALGWEKYVDGPEPIPLDDEKSVHERVDNA
                     RIDLRSKYYVKPKADHPWLTRRTQSHQQVKPPKLPKKKPDPDKKD"
     gene            complement(2442..2729)
                     /locus_tag="RH288_003844"
                     /pseudo
     CDS             complement(2442..2729)
                     /locus_tag="RH288_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001689479.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3340..3696)
                     /locus_tag="RH288_003845"
     CDS             complement(3340..3696)
                     /locus_tag="RH288_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001384020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDV4032855.1"
                     /translation="MSAPATILDMCCGSRMFWFDKSDERAIFSDIRKEGYTLRNGRRL
                     IISPDIIADFRALSFADASFSMVVLDPPHLESVGDNAWMGKKYGRLNKDAWRDDSRQR
                     FKEAFRVLRPHGVLIF"
     gene            complement(3693..4115)
                     /locus_tag="RH288_003846"
     CDS             complement(3693..4115)
                     /locus_tag="RH288_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HDV4032856.1"
                     /translation="MAKVFTQEEREKIKWQVVELVRQSGRETLRQLEAKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKVKKPAVVDPDLIWSSPDG
                     EIRRYDSRLNIICRECRKSEVMQRILAFYQGNFQDVAQ"
     gene            complement(4156..5121)
                     /locus_tag="RH288_003847"
     CDS             complement(4156..5121)
                     /locus_tag="RH288_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032857.1"
                     /translation="MSLLFAERPLVINTQLAMKIGLNEAIVLQQLHYWLRDTNSGMEC
                     DGVRWIYNTTEQWLEQFPFWSESTLKRAFASLKTLGLLRCEKLNKSKRDMTNFYTINY
                     GSELLDGGKLSESIGSKCAAPSGQNDTMEEVKMKRSIGSKRPNVIGSKWPDDLTENTT
                     EITTENKNTFRPEASQPDPQTTEQDFLTRNSDAVVFSAKKRQWGSREDLACAQWIWGR
                     IVGLYEQAASDDGEIMRPKEPNWTAWANDVRTMRMLDGRSHRQICEMFGRVQRDPFWV
                     KNIMSPSKLREKWDELVIRLGRSPVQRCVNHISEPDTEIPPGFRG"
     gene            complement(5102..5623)
                     /locus_tag="RH288_003848"
     CDS             complement(5102..5623)
                     /locus_tag="RH288_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001578395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032858.1"
                     /translation="MKITPEQAREALDAWICRPGMTQEQATILITEAFWALKERPNID
                     VQRVTYEGGAIDQRALGVNRVKIFERWKAIDTRDKREKFTALVPAIMEAIRINDFRLY
                     REITDGKSITCMIAGLNKEYGDVVESGLLFADPAVVDRETDELIEKAIAFKLAYRQQY
                     QQKAGWNYEPSFC"
     gene            complement(5607..5837)
                     /gene="dicC"
                     /locus_tag="RH288_003849"
                     /pseudo
     CDS             complement(5607..5837)
                     /gene="dicC"
                     /locus_tag="RH288_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416087.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dicB transcriptional regulator DicC"
     gene            5921..6328
                     /gene="dicA"
                     /locus_tag="RH288_003850"
     CDS             5921..6328
                     /gene="dicA"
                     /locus_tag="RH288_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional dual regulator DicA"
                     /protein_id="HDV4032859.1"
                     /translation="METKNLTIGERIRYRRKNLKHTQRSLAKALKISHVSVSQWERGD
                     SEPTGKNLFALSKVLQCSPTWILFGDEDKQPTPPVEKPVALSPKELELLELFNALPES
                     EQDTQLAEMRARVKNFNKLFEELLKARQRTNKR"
     gene            6495..6650
                     /locus_tag="RH288_003851"
     CDS             6495..6650
                     /locus_tag="RH288_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HDV4032860.1"
                     /translation="MDTIDLGNNESLVYGVFPNQDGTFTAMTYTKSKTFKTENGARRW
                     LERNSGE"
     gene            6810..7028
                     /locus_tag="RH288_003852"
     CDS             6810..7028
                     /locus_tag="RH288_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032861.1"
                     /translation="MQKREPVIIAPDYTDDELYEWMRQKINAAQDLKWANEARAKQAE
                     NLSALEQDITNLEKAAALSIARMITYPR"
     gene            7596..7784
                     /gene="dicB"
                     /locus_tag="RH288_003853"
                     /gene_synonym="ftsT"
     CDS             7596..7784
                     /gene="dicB"
                     /locus_tag="RH288_003853"
                     /gene_synonym="ftsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HDV4032862.1"
                     /translation="MKTLLPNVNTSEGCFEIGVTISNPVFTEDAINKRKQERELLNKI
                     CIVSMLARLRLMPKGCAQ"
     gene            7781..7972
                     /gene="ydfD"
                     /locus_tag="RH288_003854"
     CDS             7781..7972
                     /gene="ydfD"
                     /locus_tag="RH288_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein YdfD"
                     /protein_id="HDV4032863.1"
                     /translation="MNSAFVLVLTVFLVSGEPVDIAVSVHRTMQECMTAATEQKIPGN
                     CYPVDKVIHQDNIEIPAGL"
     gene            8065..10536
                     /locus_tag="RH288_003855"
     CDS             8065..10536
                     /locus_tag="RH288_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HDV4032864.1"
                     /translation="MSKVFICAAIPDELATREEGAVAVATAIEAGDERRARAKFHWQF
                     LEHYPAAQDCAYKFIVCEDKPGIPRPALDSWDAEYMQENRWDEESASFVPVETESDPM
                     NVTFDKLAPEVQNAVMVKFDTCENITVDMVISAQELLQEDMATFDGHIVEALMKMPEV
                     NAMYPELKLHAIGWVKHKCIPGAKWPEIQAEMRIWKKRREGERKETGKYTSVVDLARA
                     RANQQYTENSTGKISPVIAAIHREYKQTWKTLDDELAYALWPSDVDAGNIDGSIHRWA
                     KKEVIDNDREDWKRISASMRKQPDALRYDRQTIFGLVRERPIDIHKDPVALNKYICEY
                     LTTKGVFENEETDLGTVDVLQSSETQTDAVETEVSDIPKNETAPEAEPSVEREGPFYF
                     LFADKDGEKYGRANKLSGLDKALAAGATEITKEEYFARKNGTYTGLPQNVDTAEDSEQ
                     PEPIKVTADEVNKIMQAANISQPDADKLLAASRGEFVEGISDPNDPKWVKGLQTRDSV
                     NQNQHESERNYQKAEQNSPNALQNEPETKQPEPVAQQEVEKVCTACGQTGGGNCPDCG
                     AVMGDATYQETFDEEYQVEVQEDDPEEMEGAEHPHKENTGGNQHHNSDNETGETADHP
                     IKVNGHHEITSTSRTCDHLMIDLETMGKNPDAPIISIGAIFFDPQTGDMGPEFSKTID
                     LETAGGVIDRDTIKWWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVQVWG
                     NGANFDNTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERHNA
                     LDDARYQAKYVSVIWQKLIPSQADS"
     gene            10609..10860
                     /locus_tag="RH288_003856"
     CDS             10609..10860
                     /locus_tag="RH288_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family protein"
                     /protein_id="HDV4032865.1"
                     /translation="MSEVIMIVSPGKWVSEEQLIALKGIKKGTLKKAREKSFMEGREY
                     KHVAHDGMPWDNSPCFYNLEEIDRWIERQASARPRRHLT"
     gene            10895..>12148
                     /locus_tag="RH288_003857"
     CDS             10895..>12148
                     /locus_tag="RH288_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDV4032866.1"
                     /translation="MKYPTGVENHGGKLRIWFVYKDVRVRENLGVPDTAKNRRVAGEL
                     RSSVCYAIKTGVFDYAKQFPSSRNLEKFGEARQDLTIKELAEKFLALKETEVAKTSLN
                     TYRAVIKNILSIIGEKNLASSINKEKLLEVRKELLTGYQIPKSNYIVTQPGRSAVTVN
                     NYMTNLNAVFQFGVDNGYLADNPFKGISPLKESRTIPDPLSREEFIRLIDACRNQQAK
                     NLWCVSVYTGVRPGELCALGWEDIDLKNGTMMIRRNLAKDRFTVPKTQAGTNRVIHLI
                     KPAIDALRSQMTLTRLSKEHIIDVHLREYGRTEKQKCTFVFQPEVSARVKNYGDHFTV
                     DSIRQMWDAAIKRAGLRHRKSYQSRHTYACWSLTAGANPAFIANQMGHADAQMVFQVY
                     GKWMSENNNAQVALLNTQLSEYAPTM"
BASE COUNT         3430 a         2896 c         2677 g         3145 t
ORIGIN      
        1 aatttctgat agttaacatt acaagatata agtaatggac gcactcccaa ttagtctatt
       61 taaatcgcca cgagtttaac tgacaaccca tgatcaatta tgaattgcaa ctatttctgt
      121 agtcactttt gtggggacag tccacaaaac tgccaacttc cgcttcttgc tcttagcgga
      181 cattagcata ggctatttac cataacgcct cattacgcgc accgcccaga ctgactcagc
      241 gcgtttctgg catatccccg gtaaaacaag taacaaacca cccgaaaatg aacaccagaa
      301 acgcgactta agaatctacc ctatgaatgg atatgcactc aaccgaatcg atcttggttt
      361 caatcttttt tatcgggatc aggcttcttt ttaggtaact tcgggggctt aacttgctga
      421 tgactttgcg ttcggcgcgt aagccaggga tggtcagctt taggtttaac atagtatttt
      481 gagcgtaaat caatacgggc attatccact cgttcatgga cactcttttc atcatccagt
      541 ggtataggct ccgggccatc aacatacttt tcccagccca gcgctttccc gtcatacaga
      601 acgttaattt caccgtcaaa gttctcgcat acagtaacaa ccgaatgcct aagtcgatat
      661 ccccggccct cactgcgtac ctgaaacgca ctgcttttgt actggaaagt gagattttta
      721 gacagaacgc gcttcgcctg taggctgaag atataaccca gttcctcttc agaatggtgc
      781 acatcaagat gagcattatc agtagtacga ggcgacgtag cgaaccggtt gttataggct
      841 tcaataaagg tcggcaacca tgcatttgct gtttcaatat cactgatatt ctgaagccgc
      901 atttctttga ccagcctgtc ctgtagtgtc tgattggcgc gctctacccg cccttttgcc
      961 tgcgggctgt tggcatggat tggctcgatg cccagtgtct ttatcgcacg agtgaactgg
     1021 gtcagctcac cttcccgctc tgggttattt accctgaata tactgtgtct atcagagtag
     1081 agagcgagcg gtacgccatg atcattaagg taaccccgga gggtttccat gtaagcccgg
     1141 gttgtttcag caggcacaaa acgcaacgcc atcaacgcac tggtggcatc atcaatgaaa
     1201 acgatcagtg tacatctggg gcctcgattt tcaaaccagt catgaggtga gccatcaatc
     1261 tggatcagtt caccgtaaga tggtcgtcgc atgcggcgtt gatatatacg ggcaatttta
     1321 cgacggcgtt cacgccataa cccctcttct atcatccact ttctgagagt ttcaacggat
     1381 aaagataaac cgtgtatctc gcgcaatttt tcgcacgcaa acgtaggtcc aaaatcagcg
     1441 taacggcctt tgaggagtga aattactgtt gctctgaatt cagtagaaaa ggaattatta
     1501 ggacgctttc cacgtcggtg ggaaaccaga ccagaaggcc cttcatttct ataccgttgc
     1561 accagacgtt taacctgccg aatagaaatg ccaatgcgtg ccgcagcttg ttcctgaata
     1621 atctgaagtc ggtggagttc cttatgactc atcgtaacag tctctttgat catgaaaaat
     1681 cccccagaga attgtctggg gacattttag aatggttcaa aggggacatt acagcttggt
     1741 gttaacaata gcctgcttct ccgtgccttt cggcacgtaa gaggctaacc tacatgtgtc
     1801 tagcatgaaa ttggcctcag attaatgtta agcgtcttgc aggacgcgta atgttaactg
     1861 gggcttttct ctatctgccg ttggtgtcca tgcccgaggc agatagcctc aagcacccgc
     1921 agtcattcta cttaactaag atttccccgc aaaccgtttt tgtccagcac agtaaatatc
     1981 caactaaacc aatggagttc gctgtattta ccgccagtat tcaatgcaca tgaccgccat
     2041 gaacacccct aaaaaaaggg catttatata tccaaatatt aatatcaaaa catcaacttt
     2101 ttccatatac cttgctgtga agatgatggg catacatgat gcgaacaacc agaacgcaac
     2161 aaacaaaaac tgcaatgcgt ttttcattat tcctcctaca atcaatgtgc aattacattt
     2221 aaacacacct caatttggcc ggacatataa atatctaaac cagaaaaaat cacttacata
     2281 gcgttacaaa ctctttagtc taaaggttca tcgtaaaaca ttccccatac ttatcagtcc
     2341 gttccgcgcc aggtagctca ttgccttatc tggcaacctg taatcaggtt tccgcttttt
     2401 cagttggctg gtcgtttaac cgacatagtt aatccattaa tctagttgcc ggatgttggt
     2461 ggattttcgc gttttagttg ttcataaaag tgcacagctt taaccagttc ttctgatgta
     2521 actgggactg gtgaggcagt gaataaggcc tgaatttgat agttcggcct gtcgttacaa
     2581 tcctcttttt tcggtacata tttccagtca ccagaccact acttcccctg aaagtccgta
     2641 acgccttttt tcacgtagcg atatcgccat gccactggtt ttgcttgccc cgccgtttca
     2701 tgcccttcct gataattaat ctcgctcatt catcgcccca ctcatcacaa tatgcttcga
     2761 ccggagtttt tcccgcttca tagtcatcac gctaggattc gacatcagca gcacttccac
     2821 cgcgtaactc accatagtcc attaatagtt catcccgctc ttcaaaactg atgttatatt
     2881 tagctgaaca aaaatcagcc actttgttct tcctcatcgt cttttatttc gtggtatgag
     2941 taattgcagt agttaaagaa aatttcttat gctccgtcat gaatttcctc aggtgttgcg
     3001 tcatcgtcca cttcgaatac atcctcaaaa tctccaccag ctattcccgt ttcaataata
     3061 attttgaact ttcgcatttc actaccgccc tttcgggcgg cctcctgatg ttctgagggt
     3121 gcagaaatcc atccggttaa ggattaaatt ttatttacag aactgaattt aattattcag
     3181 atatacgtat ctgtagcctt acgaatctac tcactggatg cctctttcat aaaaataatc
     3241 cagtgggttt tatcgttttt tccctgttcg ttgacagata acaggttttc tgtctgtcag
     3301 tgccagaatc tggcttaccg gtatttgcgt ttcattccat taaaaaatca gaacgccgtg
     3361 cggcctcaac acccgaaagg cttctttaaa tctctgtcgc gaatcatcac gccaggcatc
     3421 tttattcagc cgtccatatt tctttcccat ccaggcgtta tcaccaacac tctcaagatg
     3481 cggagggtct aatacaacca tcgaaaaaga tgcgtctgca aatgataatg cacgaaaatc
     3541 tgcgataatg tcagggctga taatcaagcg tctcccattg cgtaatgtgt atccttcttt
     3601 tctgatatcg ctgaatatcg cccgttcgtc agacttatcg aaccagaaca tgcggctgcc
     3661 acagcacata tcaagaatgg ttgccggtgc actcactgcg ccacgtcctg aaaattaccc
     3721 tgatagaaag ccagtatgcg ctgcataact tcgctcttcc ggcactcgcg acagattatg
     3781 tttaggcgac tgtcgtagcg acgtatttct ccgtcaggtg atgaccagat aaggtccgga
     3841 tcaaccacag caggtttctt cacctttgcc ctcgagagtt ttttgcgggc gttttgccag
     3901 tccttacgcg cctgttcaga ggggaataac ccgtagccgg agttgtatac atcgccactg
     3961 gctaccagct ctctggcaag aacgctcatc agatatctag tcgcacctgt tttagcttcc
     4021 agttgccgta acgtctcacg gccgctctgg cgcacgagtt ccaccacctg ccatttaatt
     4081 ttttcccgct cttcttgtgt aaaaactttt gccacaagtc ccccttaaaa ttacctcatg
     4141 acctgaaatc aacacttatc ctctgaaacc aggcggaatt tctgtatccg gttcagaaat
     4201 atgattaaca caacgctgta caggtgaacg tcccaggcgg atgaccagtt cgtcccattt
     4261 ttcgcggagc tttgacgggc tcatgatgtt ttttacccag aatggatctc gctgaacccg
     4321 accaaacatt tcgcaaattt gtctgtggct tctgccatcc agcatccgca ttgtgcgcac
     4381 gtcattggcc caggcagtcc agttaggctc ttttggtcgc atgatctcgc catcatcact
     4441 ggctgcctgt tcgtagagac ccacgatccg cccccagatc cactgcgcac acgccaaatc
     4501 ctccctgcta ccccactggc gttttttcgc actaaacaca accgcgtcgg agttccgggt
     4561 taaaaaatcc tgttcagtcg tctgcgggtc cggttgcgaa gcttccggac gaaaagtgtt
     4621 tttattctct gtagtaatct ctgttgtatt ctctgtaaga tcatcaggcc attttgaccc
     4681 gatgacattg ggtcgttttg aaccaatgga gcgtttcatt ttgacctctt ccatcgtgtc
     4741 attttgacct gatggagcgg cgcattttga accgatggat tcgctcaatt tgccaccatc
     4801 taaaagctcg ctcccatagt tgatcgtgta gaaattggtc atatcgcgct ttgatttatt
     4861 gagcttttca caacgcaaaa gccccagcgt tttcagactt gcaaacgcgc gctttaacgt
     4921 tgactctgac cagaatggga actgttccag ccattgttcc gttgtgttat aaatccagcg
     4981 aacaccatca cattccatgc cggagttggt atctctcaac cagtagtgca gttgttgcaa
     5041 aacaatggct tcgtttaagc caattttcat tgccagctgc gtgtttataa ccagtgggcg
     5101 ttcagcaaaa agaaggctca taattccatc cagctttttg ttggtattgc tgtcgatacg
     5161 caagtttgaa agcaattgct ttttctataa gttcgtcagt ttcacgatcc actacggcag
     5221 gatcagcaaa aagcagtccg gactccacca catcgccata ttctttgttt aacccggcga
     5281 tcatgcacgt gatgcttttt ccgtcagtaa tttcacgata caacctgaaa tcattaatac
     5341 ggatagcctc cataattgca ggcactagcg ccgtgaactt ttcacgctta tccctggtgt
     5401 cgatagcctt ccagcgttca aatatcttca ctcgattaac gccaagcgct cgctgatcaa
     5461 tcgcgccacc ttcatatgtg acacgctgaa catcgatgtt cgggcgctct ttcaaagccc
     5521 agaatgcttc agtgattaat atcgtcgcct gctcctgtgt cattcctggt cgacatatcc
     5581 aggcatccag agcctcacga gcctgttcag gagtgatttt cattgttcaa ccgccccgcc
     5641 cgcttcgtct tacgatattc atcataaact ttgggatcat actgaagctc cccgccagat
     5701 gcctcctgtt aacgcatcgc gcgaccttcg ggaactaaat cccctttcca gctataaagc
     5761 gaagccaaac gaatacctgc tgcttgtgca agttttgttt ttgaaccgaa atacaaaaga
     5821 gcgtcagttt taagcattta aaacaccttt attgttagtc ataactaaca agatagatgt
     5881 taacaaaaac atagtcaata cgatttagca ttagctaact atggaaacaa aaaatttaac
     5941 tatcggcgaa cgcatcaggt atcgtcggaa aaacctcaaa cacacccaaa ggtctcttgc
     6001 taaagccctg aaaatctccc atgtgtctgt atcacaatgg gaacggggtg atagtgaacc
     6061 tacagggaag aacctttttg ccctcagcaa agtattgcaa tgctcaccaa catggattct
     6121 atttggcgat gaagacaagc aaccaacacc acctgttgag aagccagttg ccttatcccc
     6181 caaagaacta gagctccttg agctgtttaa tgcactgcca gaatcagaac aggataccca
     6241 gctcgccgaa atgcgagctc gagtaaaaaa cttcaataaa ctctttgaag aattactaaa
     6301 agcccgtcag cggacaaata aaagataaca tcatcaatga gttatctttt accacatcaa
     6361 ttatgttagc tatagcatac aaaatcactt gaccgatatg ttagtcatgg ctaatcttgt
     6421 ttgcatcaac acactgcacg gtgttctcag caaacagttc cgctacccca gcgttaaggg
     6481 gaaatgaggt cagcatggat actatcgatc ttggcaacaa cgaatctctg gtgtacggcg
     6541 tgtttccaaa ccaggacggc acgttcaccg caatgacgta taccaaaagc aaaacgttta
     6601 aaaccgaaaa tggtgcccgt cgctggctgg aaagaaactc aggtgagtga tatggatttc
     6661 gacacaatca tggaaaaggc ttacgaagaa tacttcgaag gccttgccga aggcgaagaa
     6721 gctctcagct tcagtgagtt taaacaggcg ctttccagtt cggcaaaatc taacggctga
     6781 taagcgaaac agcaccgcga ggaatcagta tgcagaaacg agaacccgtc atcatcgcgc
     6841 cagactatac cgatgatgaa ctttatgagt ggatgcgcca gaaaattaat gcagcgcagg
     6901 atctgaaatg ggctaatgaa gccagggcta agcaggctga aaatctgtcc gctctggagc
     6961 aggatatcac caatctggaa aaagcagcgg cattaagcat tgccagaatg attacatacc
     7021 cgcgttagta gctaatcaac aaagctaagg ttagtaatta aggagttctc cacgggtgag
     7081 gtggagtgcg tgcgccggac acgggtgcgc atccggaact gacagtttac tgaaaggata
     7141 tttccctgaa aagtcagacc ataacgcgaa agcgcacggc gaggtagctg gttcatagat
     7201 agcctgtcgt taaattttcg tcgaccgtgc gcttccggtt gtggcaaccc gcgaaatggc
     7261 gcggcggtaa gtatggcggg gttattcctt ccccgttgag gacaccgggt tgtcaggttg
     7321 accatacgct taagtgacaa ccccgctgca acgccctctg ttatcaattt tctggtgacg
     7381 tttggcggta tcagttttac tccgtgactg ctctgccgcc ctttttaaag tgaattttgt
     7441 gatgtggtga atgcggctga gcgcacgcgg aacagttaaa accaaaaaca gtgttatggg
     7501 tggattctct gtatccggcg ttaattgtta actggttaac gtcacctgga ggcaccaggc
     7561 actgcatcac aaaattcatt gttgaggacg cgataatgaa aacgttatta ccaaacgtta
     7621 atacgtctga aggttgtttt gaaattggtg tcactatcag taacccagta tttactgaag
     7681 atgccattaa caagagaaaa caagaacggg agctattaaa taaaatatgc attgtttcaa
     7741 tgctggctcg tttacgtctg atgccaaaag gatgtgcaca atgaattcag catttgtgct
     7801 tgttctgaca gtttttcttg tttccggaga gccagttgat attgcagtca gtgttcacag
     7861 gacaatgcag gagtgtatga ctgcagcaac cgaacagaaa attcccggta actgttaccc
     7921 ggtcgataaa gttattcacc aggataatat cgaaatcccg gcaggtcttt aaaacagttc
     7981 cgtaataaat atccggtttc attcttatat gccagcaatg gcagggattt gttcatcctt
     8041 aaatctgtca tgaggttaaa acaaatgagt aaagtcttta tttgcgccgc tattcctgac
     8101 gaactggcaa caagggaaga aggcgctgtg gctgtagcca cagccattga agctggcgac
     8161 gaacgccgtg ctcgagcaaa atttcactgg caattcctgg aacattatcc ggctgctcag
     8221 gactgcgctt ataaatttat tgtctgcgag gataaacctg gcataccccg ccctgccctc
     8281 gattcatggg atgctgaata tatgcaggaa aaccgctggg atgaggagtc tgcttctttt
     8341 gtcccggttg agactgaatc cgatccgatg aacgtcactt ttgacaagct ggcccctgaa
     8401 gtacagaacg ctgtcatggt taagttcgac acatgtgaaa acatcaccgt tgatatggtt
     8461 attagcgcac aggaattgtt gcaggaagac atggcaacat tcgacggaca tatcgttgaa
     8521 gcgttgatga aaatgccaga agttaacgcc atgtatccgg agcttaagtt gcacgccatt
     8581 gggtgggtta agcataaatg tattcctggt gctaaatggc ccgaaattca ggcagagatg
     8641 cgcatctgga aaaaacgtcg cgaaggtgaa cgcaaggaaa ccggaaaata cacgtctgtt
     8701 gttgatctcg cccgcgccag agccaatcaa cagtacactg aaaattcaac aggaaaaatc
     8761 agcccggtca ttgctgccat tcatcgcgaa tacaagcaga catggaaaac actggatgac
     8821 gaactggcct acgctctctg gcctagtgat gtggatgccg gaaacattga cggcagcatc
     8881 catcgctggg caaaaaaaga agttatcgac aacgaccgcg aagactggaa gcgtatctcg
     8941 gcatcaatgc gcaaacagcc tgatgccctt cgctacgacc gccaaactat ttttggcctt
     9001 gtccgtgagc gtccgatcga cattcacaaa gatcccgtag cactgaacaa atatatctgc
     9061 gaatacctga cgacaaaggg cgtgtttgag aatgaagaaa cagacctggg cactgttgat
     9121 gttctccagt catcagaaac acaaactgat gcagtggaaa ctgaggtatc tgatatccca
     9181 aaaaatgaaa ccgcgccgga agctgaacca tctgtagagc gtgaggggcc gttctatttc
     9241 ctcttcgcag ataaggacgg agaaaaatac ggtcgcgcaa acaaactctc tggtctggat
     9301 aaggcactgg ctgctggcgc cactgaaatc acaaaagaag aatattttgc ccgaaaaaat
     9361 ggcacataca cgggcttacc gcaaaatgta gataccgctg aagattcaga acaaccagag
     9421 ccgataaaag ttaccgctga cgaagtaaac aaaattatgc aggcagccaa tatcagccag
     9481 cctgacgccg ataagttgct tgctgcatca cgtggtgaat ttgttgaagg gattagtgac
     9541 ccgaatgatc cgaaatgggt taaggggctc cagacccgcg attctgtgaa ccagaaccag
     9601 catgaatcgg aacggaacta ccaaaaagcg gaacaaaaca gtccaaatgc gttacaaaac
     9661 gagccagaaa cgaaacagcc tgaaccagta gcgcaacagg aagtggaaaa agtctgcacc
     9721 gcctgcggtc agaccggcgg cggcaactgc cctgattgtg gcgcggtgat gggcgacgca
     9781 acataccaag aaacattcga tgaagagtat caggttgaag ttcaggaaga tgatccggag
     9841 gaaatggaag gcgctgaaca tccacacaag gagaacactg gcggcaatca gcatcacaat
     9901 agcgataatg aaactggcga gacggcagat cacccaatta aggtgaacgg tcatcacgaa
     9961 atcacatcca ccagcaggac gtgtgaccat ctaatgatcg accttgaaac catgggaaaa
    10021 aatcctgatg ccccgatcat ctcaataggt gcaatatttt tcgatccgca aaccggagat
    10081 atgggaccgg aatttagtaa gactatcgat ctggaaactg ctggcggagt cattgatcgg
    10141 gacaccatta aatggtggct taagcaatca cgcgaagcgc aatctgccat tatgaccgat
    10201 gaaatcccgt tagatgatgc actgttacaa ttgcgagaat ttatcgacga aaactccggt
    10261 gaattttttg ttcaggtttg gggaaatgga gccaacttcg acaacacgat tttgcgccgt
    10321 tcatacgaac ggcaggggat cccctgcccg tggcgttact acaacgatcg cgatgtacgc
    10381 acaatcgttg agctggggaa agccatagac ttcgatgcca gaacggctat tccattcgaa
    10441 ggtgagcgcc ataatgcact tgatgacgcc cgttaccagg caaaatacgt ttcagttatc
    10501 tggcaaaaac tgatcccgag tcaggctgat tcttaatgtt caactgtcgc cggttgtgac
    10561 tggtattctg caaccggcgc tcgtctgatg taagagataa agaaatcgat gagcgaagta
    10621 atcatgattg tctctcccgg caaatgggta tccgaagagc agttaattgc gctgaaagga
    10681 ataaaaaaag gtacgttaaa aaaggcccgg gaaaaatcgt ttatggaagg aagggaatat
    10741 aagcatgtcg ctcatgacgg tatgccatgg gataacagtc catgctttta caacctggaa
    10801 gaaattgatc gctggattga gcgccaggca tcagcgagac caagacgtca tcttacttga
    10861 ctaaaagcca cactaactaa tgagagaagt tgaaatgaaa tatccgacag gcgtggaaaa
    10921 ccatggaggg aaattacgta tctggtttgt ttataaagac gtaagagtca gggaaaatct
    10981 gggggttcct gacacagcaa aaaacaggcg cgttgcaggt gaactacgct cctctgtttg
    11041 ttacgcaata aaaactggtg ttttcgacta tgcaaaacag tttccctcct cacgcaatct
    11101 ggaaaaattt ggtgaggccc gacaagattt aaccataaaa gaactggctg aaaaatttct
    11161 ggcactgaaa gaaactgaag tcgccaaaac atcactcaac acataccgtg ccgtcatcaa
    11221 aaatatcctg agcataatcg gtgaaaaaaa tcttgcctca tcgattaata aagaaaaatt
    11281 actggaggtt cgtaaagagt tactgactgg ataccagatc cccaaaagta actatattgt
    11341 tacacaacca gggagatcgg ctgtaactgt aaataattac atgacaaatc ttaacgccgt
    11401 gttccagttt ggtgttgata acggttacct ggcagataat ccgtttaagg ggatctcgcc
    11461 attaaaggaa tcaagaacca ttccggatcc tctttcgcgg gaagaattta tccgtcttat
    11521 cgatgcgtgc agaaatcagc aagcaaaaaa tttatggtgt gtttctgttt atactggagt
    11581 tcgccctggt gagctgtgtg cacttggatg ggaggacata gatctgaaaa atggaacaat
    11641 gatgatcagg agaaatttag caaaagaccg tttcacggta ccaaaaacac aggcgggaac
    11701 caatcgggtc attcatctta ttaagccagc aatcgacgct ctccggagtc agatgacatt
    11761 aacgagactg agcaaagagc atatcattga tgttcacctc agagagtatg gcagaacaga
    11821 aaaacaaaaa tgcacctttg tttttcaacc tgaagtgtca gcgagagtaa aaaattatgg
    11881 tgaccatttt accgttgact caataaggca gatgtgggac gcagcgataa aacgtgccgg
    11941 actccgccat cgaaaatcat atcagtcgag acatacttat gcctgctggt cgctgacagc
    12001 tggtgctaac ccggcattta tagcaaacca gatgggccat gcagatgcgc aaatggtatt
    12061 tcaggtatac ggaaaatgga tgtctgaaaa caataatgca caggtagctt tgttaaatac
    12121 acagttaagc gagtatgccc caaccatg
//
LOCUS       DAPHKZ010000136        11965 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.136, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000136 DAPHKZ010000000
VERSION     DAPHKZ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11965
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.136"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            4..600
                     /locus_tag="RH288_003858"
     CDS             4..600
                     /locus_tag="RH288_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HDV4032867.1"
                     /translation="MNYPAEYEIGDIVFTCIGAALFGQISAASNCWSNHVGIIIGHNG
                     EDFLVAESRVPLSTITTLSRFIKRSSNQRYAIKRLDAGLTERQKQRIVEQVPSRLRKL
                     YHTGFKYESSRQFCSKFVFDIYKEALCIPVGEIETFGELLNSNPNAKLTFWKFWFLGS
                     IPWERKTVTPASLWHHPGLVLIHAEGVETPQPELTEAV"
     gene            complement(602..1123)
                     /gene="ruvC"
                     /locus_tag="RH288_003859"
     CDS             complement(602..1123)
                     /gene="ruvC"
                     /locus_tag="RH288_003859"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDV4032868.1"
                     /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(1158..1898)
                     /locus_tag="RH288_003860"
     CDS             complement(1158..1898)
                     /locus_tag="RH288_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV4032869.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAVDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(1927..2379)
                     /gene="nudB"
                     /locus_tag="RH288_003861"
     CDS             complement(1927..2379)
                     /gene="nudB"
                     /locus_tag="RH288_003861"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HDV4032870.1"
                     /translation="MKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE
                     EGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW
                     FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA"
     gene            complement(2497..4269)
                     /gene="aspS"
                     /locus_tag="RH288_003862"
     CDS             complement(2497..4269)
                     /gene="aspS"
                     /locus_tag="RH288_003862"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDV4032871.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII
                     NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI
                     DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMI
                     FFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE
                     EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANPTALAELSIQVVKKAENN"
     gene            4579..5145
                     /locus_tag="RH288_003863"
     CDS             4579..5145
                     /locus_tag="RH288_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDV4032872.1"
                     /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF
                     RASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPAALGATDSDIEIIKR
                     QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
                     AEQHNNSINHIYPRIARVRSVEEILNAL"
     gene            5142..5960
                     /locus_tag="RH288_003864"
     CDS             5142..5960
                     /locus_tag="RH288_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDV4032873.1"
                     /translation="MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKP
                     EVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQL
                     PATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNRVIL
                     DSRPVHAARPHSEAIRDAQRKKPKVPVHAVLTATNPLIRFIGSDDMTQNRELFQVWLQ
                     KLAQWHQTTTPYLFLHTPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF"
     gene            6013..6408
                     /locus_tag="RH288_003865"
     CDS             6013..6408
                     /locus_tag="RH288_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HDV4032874.1"
                     /translation="MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRS
                     GMSATWCALLLMVLANLWYMPWELVFSLR"
     gene            6449..7192
                     /gene="cmoA"
                     /locus_tag="RH288_003866"
     CDS             6449..7192
                     /gene="cmoA"
                     /locus_tag="RH288_003866"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HDV4032875.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHI
                     DAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     HNAGFEHSELWFQCFNFGSLVALKAEDAA"
     gene            7189..8160
                     /gene="cmoB"
                     /locus_tag="RH288_003867"
     CDS             7189..8160
                     /gene="cmoB"
                     /locus_tag="RH288_003867"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HDV4032876.1"
                     /translation="MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSN
                     AVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVS
                     VTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAPKRAVLIARKP"
     gene            complement(8325..10754)
                     /gene="torZ"
                     /locus_tag="RH288_003868"
     CDS             complement(8325..10754)
                     /gene="torZ"
                     /locus_tag="RH288_003868"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416386.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine N-oxide reductase TorZ"
                     /protein_id="HDV4032877.1"
                     /translation="MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRW
                     GAMNVEVKDGKIVSSTGALVKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPA
                     KGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
                     YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPL
                     NTLKIAWSSTDEQGLEYFHQLKKSGKPVIAIDPIRSETIEFFDDNATWIAPNMGTDVA
                     LMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKSAVWAAEITGVPEAQ
                     IVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYS
                     NGGNPTRVGGVLPEMSAAIAGHASEAADDGGMTAIPVARIVDALENPGGKYQLNGKEQ
                     TYPNIKMIWWAGGGNFTHHQDTNRLIKAWQKPEMIVVSECYWTAAAKHADIVLPITTS
                     FERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKPGGKEIYTEGKDE
                     MAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVK
                     NALGTPSGKIEIYSKTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLH
                     SQLNYAELRKKYAIADREPITIHTEDAARFGIANGDLVRVWNKRGQILTGAVVTDGIK
                     KGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTGNAPK
                     LTAFDQPAVQA"
     gene            complement(10779..11879)
                     /locus_tag="RH288_003869"
     CDS             complement(10779..11879)
                     /locus_tag="RH288_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HDV4032878.1"
                     /translation="MRGKKRIGLLFLLIAVVVGGGGLLLAQKALHKTSDTAFCLSCHS
                     MSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDS
                     DDKFEAHRQEMAETVWKELKATDSATCRSCHSFDAMDIASQSESAQKMHNKAQKDSET
                     CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKTSHIGELATVNPGTD
                     LTVVDASGKQPIVLLQGYQMQGSENTLYLAAGQRLALATLSEEGIKALTVNGEWQADE
                     YGNQWRQASLQGALTDPALADRKPLWQYAEKLDDTYCAGCHAPIAADHYTVNAWPSIA
                     KGMGARTSMSENELDILTRYFQYNAKDITEKQ"
BASE COUNT         2735 a         3184 c         2922 g         3124 t
ORIGIN      
        1 aatattaatt accctgctga atatgaaatt ggagatatcg tctttacatg tataggtgct
       61 gccttatttg gtcaaatatc agctgcatca aattgctgga gtaatcacgt cgggatcatt
      121 atcggtcata acggtgaaga cttcctggtt gcagaaagcc gggttcccct ttcaaccatc
      181 accacgctat ctcgttttat taaacgttcg tctaatcaac gctatgctat aaagcgatta
      241 gacgctgggc tgacagaacg acaaaaacaa cgaattgttg aacaggttcc ctcccggcta
      301 cgcaaacttt accacaccgg ttttaaatac gaatcttcgc gccagttctg ttcaaaattt
      361 gtttttgata tttataaaga agcgctatgt attccggtgg gtgaaataga gacgtttgga
      421 gaattgttaa atagcaatcc gaatgcaaaa ctcactttct ggaaattctg gttcctgggt
      481 tctattccgt gggagcgtaa aaccgtcacg ccagccagtt tgtggcatca tccgggtttg
      541 gtgttgattc atgcggaggg agtggaaacg cctcagccgg aactgaccga ggcggtataa
      601 cttaacgcag tcgccctctc gccaggttca gccgcgattc gctcatctgc atcgcattct
      661 gactaacgtg gcagtgggtg atagcaatcg ccagcgcatc ggcggcatcc gcctgtggat
      721 tagcgggcag tttcagcaag gtgcggacca tatgctgcac ctggcttttt tcggcactgc
      781 caatacctac caccgtttgc tttacctgac gtgccgcgta ttcaaatact ggcaactcct
      841 gattcaccgc cgccacaatc gccacgccgc gcgcctggcc cagtttcagg gctgagtcag
      901 cgttctttgc cataaagact tgttcaatgg cgaaataatc aggctggaac tgggtgatga
      961 tttccgtcac gcccgcatag atgagtttca gacgagacgg taaatcatcc actttggtgc
     1021 ggatgcatcc gctacccagg taggacagtt gcctacctac ctggcggatg acgccgtagc
     1081 cggtcacgcg cgaacccgga tcaatgccga gaataatagc catcacgcgt ctccgttttg
     1141 ctgtttagca ggcctcatca gagagtcgct gcgacctcat cagagatttc accgttatgg
     1201 taaacttcct gcacgtcgtc gcaatcttcc agcatatcga tcagacgcat cagtttcggt
     1261 gcggtttctg catccatatc agctttggta gacgggatca tggaaacttc cgcgctgtct
     1321 gctttcagac ctgccgcttc cagagcgtcg cgcactttac ccatttcttc ccatgcagtg
     1381 tagacatcaa tcgcgccgtc atcataggtc acaacgtctt cagcacctgc ttccagtgct
     1441 gcttccatga tggtgtcttc atcgcctttc tcgaaggaga tcacgccttt tttgctgaac
     1501 agataggcaa cggaaccatc agtaccgagg ttaccgccac atttgctaaa tgcatgacgc
     1561 acttcagcaa cggtacggtt gcggttgtca gacagacatt caatcatgat tgccgtgccg
     1621 ccaggaccgt aaccttcgta gatgatggtt tccatgtttg catcatcatc accgcccaca
     1681 ccacgtgcaa ttgcgcggtt cagtgtgtca cgggtcatgt tgttagacag tgctttatcc
     1741 accgccgcac gcagacgcgg gttagcgtcc ggatcgccac cgcccagctt agccgcggtt
     1801 accagctcac gaatgatttt agtgaagatt ttaccgcgct tagcatcctg cgcagcttta
     1861 cgatgtctgg tgttggccca tttactatga cctgccataa aaatatctcc agatagccct
     1921 gcctgttcag gcagcgttaa ttacaaactg ttcaatcgcc tgccggttgc tccaggactt
     1981 agtgagcgcc gccgcagcag gcgcatcaag ccacttgtaa gccagatgtt cagtgaaaac
     2041 gatctgccgc tcgtgcggaa gcgcaagaca gaaccatgat tccgtattac gcgtcacgcc
     2101 cggcgcatag cgatgacgta aatgtgaaaa aatttcaaac tctaccgtgc gctgacagtc
     2161 aattaaggtc agttgttcag cgacaacatc aatggtgacc tcttccttta cttcgcgcat
     2221 ggcagcttgc ggcgcggttt caccctcttc cacgctgccg gttaccgact gccagaaatc
     2281 gggatcgtca cgccgctgca acatcagcac ccgtttcgta tcttgtgcgt agatgaccac
     2341 taagatcgaa acgggacgct tatacacttt atccttcacg ctgcctcttc gttgactgcc
     2401 ttcgctcatc ccattcacat agttatctat gctcatggga gttcactcag ttgccgcctc
     2461 gatgcaacgc gaatgatttc gtgtatttga gtcatatcag ttattctcag ccttcttcac
     2521 aacctgaatg ctcagctcag ccagtgcagt cgggttagca aagctcggtg cttcagtcat
     2581 cagacacgct gccgccgtgg ttttcgggaa ggcgataacg tcacggatat tgtcggtgcc
     2641 ggtcagcagc atggtcagac ggtcaagacc gaatgccaga cctgcgtgcg gcggagtacc
     2701 gtatttcaga gcgtcgagca ggaagccgaa tttctcgcgc tgttcctctt cgttgatacc
     2761 cagaatacca aacaccgtct gctgcatatc accattatgg atacgtactg aaccaccgcc
     2821 cacttcgtaa ccattgatga ccatatcgta agcgttcgcc accgcatttt ccggtgcagc
     2881 tttcagttct gcagccgtca tatctttcgg tgaggtgaac ggatggtgca ttgccgtcag
     2941 gccgccttca ccgtcgtctt caaacatcgg gaagtcgata acccacagcg gtgcccattt
     3001 gctttcgtcg gtcagaccaa ggtctttacc cactttcaga cgcagtgcac ccatcgcgtc
     3061 ggcaacaatt ttcttgttgt cggcaccgaa gaaaatcata tcgccatctt gcgcggcagt
     3121 acgatccagg atgtcttcga tgatttctgc attaaggaac ttcgctaccg ggctgttgat
     3181 accttccaga cctttcgcgc gttcgttaac tttgatgtaa gccagacctt tcgcgccgta
     3241 gattttaacg aagttaccgt attcgtcgat ctgcttacgg gtcagcgatg cgccgcccgg
     3301 aacgcgcaga gccgctacgc gacctttcgg atcgttcgcc ggacctgcaa atacagcaaa
     3361 ctcaacagat ttcagcagat cagcaacgtc agtcagttcc atcgggttac gcagatccgg
     3421 tttatcagaa ccataacggc gttctgcttc cgcaaaggtc attaccggga aatcgcccag
     3481 atccacaccc ttcacttcca gccacagatg acgcaccagc gcttccatca cttcacgcac
     3541 ttgcggcgcg gtcatgaaag aagtttccac atcgatctga gtaaattcag gctgacggtc
     3601 agcacgcagg tcttcgtcac ggaagcattt aacgatctga tagtaacggt caaaaccgga
     3661 catcatcagc agctgtttga acaactgcgg ggattgcggc agtgcgtaga atttaccttt
     3721 gtgcacacga gaaggcacca ggtagtcacg cgcgccttcc ggcgtggctt tggtcagcat
     3781 cggagtttcg atgtcgagga agccgtggtc atccataaaa cggcgcacca ggctggtgat
     3841 tttagcgcgg gttttcaggc gctgagccat ttccggacga cgcaggtcga ggtagcggta
     3901 tttcagacgc gcttcttcgg tgttgacgtg gttagagtca agcggcagaa catctgcgcg
     3961 gttgatgata gtcagcgagg acgccagcac ttcgatttcg ccggtcgcca tatcgcggtt
     4021 aatatttttt tcgtcacgcg cacgtacggt gcccgtgacc tgaatgcaga actcattacg
     4081 cagttcagag gccagcttta acgcgtccgc acgatccgga tcgaaaaata cctgcacgat
     4141 accttcgcgg tcgcgcatat cgatgaagat caggctacca agatcacgac gacggttgac
     4201 ccaaccacac agagtcacct gctgccccac gtgggacaaa cggagctgtc cacaatattc
     4261 tgtacgcatg agatatccct taacttagct gccggcggat gccccctgct gcgcaggtga
     4321 ccaagtcgca gcgttagctg tatgtcacaa ctgaatgaaa aaaggcggct attatactgg
     4381 aaattctgcc gcaccgtaag agcctggccc gcgctggaac gcctcgttac cactttatat
     4441 cgggcctgaa atcagactct acgccagttt gctataaagg tgttgcccga actcataaaa
     4501 attaacaaaa tttgtcgttc cgccatcggc taatcgcatt aaggtgtgag gcacgatttt
     4561 gttttttcag gagtcatgat gcttgaactt aatgctaaaa ccactgcgct ggtggtgatc
     4621 gatttacaag aaggcatctt accttttgcc ggtggtccac atactgccga tgaggtagtt
     4681 aatcgcgccg ggaagctggc ggcgaaattt cgcgccagcg gtcagcccgt gtttctggtg
     4741 cgcgttggct ggtctgccga ttacgctgaa gcattaaaac agccggtcga tgcgccctca
     4801 ccggctaaag tgttgcccga aaattggtgg caacatcctg ctgcattagg tgcaaccgac
     4861 agcgatatcg aaatcatcaa acgtcaatgg ggtgcgtttt acggtacgga tctggagttg
     4921 caattacgcc gccgaggtat cgatacaata gtgttatgtg ggatctcgac caatatcggt
     4981 gttgaatcca ccgcccgcaa tgcctgggaa cttggcttta atctggtgat tgccgaagac
     5041 gcctgtagtg ccgccagcgc cgagcagcac aataacagta tcaaccatat ctacccgcgc
     5101 atcgcccgtg tgcgtagcgt ggaagagatc ctcaacgcgt tatgatttac atcggtctac
     5161 cgcaatggtc gcatcctaaa tgggtgcggt tggggatcac cagccttgaa gagtatgccc
     5221 gccactttaa ctgcgtggag ggcaacacca cgctttacgc cctgccgaaa cccgaggttg
     5281 tcctgcgctg gcgtgagcag accacagatg acttccgctt ctgttttaag tttccggcga
     5341 ccatttcgca tcaggcagca ttacggcatt gcgatgattt agtgactgaa tttttgaccc
     5401 gcatgtcacc gttggctccg cgcattgggc aatactggct gcaactgcct gccacattcg
     5461 gcccacggga gctgcctgcg ctttggcatt ttctcgattc tcttcctggc gaatttaatt
     5521 atggcgtgga agtccgccat ccacagtttt tcgccaaagg agaagaggaa caaacgctta
     5581 atcgcggttt acatcagcgc ggcgttaatc gggtgatttt agacagccgc ccggttcatg
     5641 cagcacgtcc acacagtgaa gctattcgcg acgctcaacg aaaaaaacct aaagttccgg
     5701 tacatgctgt actgacggcg acaaatccgc tgatccgttt tatcggtagt gatgatatga
     5761 cgcaaaaccg ggaattattt caggtctggt tacaaaaatt agcgcagtgg catcagacca
     5821 ctacgcctta tcttttttta catacgccag acattgccca ggcaccggaa ctggtacata
     5881 ccctgtggga agacttacgt aaaacgcttc cagagatcgg agcagttccg gctattccac
     5941 agcaatcttc tcttttctga atttgccacc tatcatagac aggtgccatc ggccatttta
     6001 aagggagttt gtatggtaag cgcgctgtac gccgttttaa gtgcgttgtt attaatgaag
     6061 ttctcttttg atgtcgttcg cctgcgaatg cagtaccgcg ttgcctatgg cgacggcggt
     6121 tttagcgaac tgcaaagcgc tattcgcatt catggtaacg cggtggaata tattcccatc
     6181 gcgattgtgc tgatgctgtt tatggaaatg aatggcgcag aaacctggat ggtgcatatt
     6241 tgcggcatcg ttttgcttgc tggtcgtctg atgcattatt acggttttca tcaccgtctg
     6301 ttccgctggc gacgttccgg catgagcgcc acctggtgtg cgctgttgct gatggtgctg
     6361 gcgaatcttt ggtatatgcc ctgggagttg gttttctccc tgcgttagcg cacaatacgc
     6421 cactttcttt ttcccggatt tttacgttat gtctcaccgc gacacgctat tttctgcccc
     6481 tatcgccaga ctgggcgact ggacctttga tgaacgggta gctgaagtct tcccggatat
     6541 gatccagcgt tccgtacccg gctattccaa tattatttcc atgattggta tgttagccga
     6601 gcgcttcgtt caacctggta cgcaggttta cgatctgggt tgttctctgg gcgcggcgac
     6661 gctctcggtg cgtcgcaaca ttcatcatga taattgcaaa attattgcca tcgacaactc
     6721 cccggcgatg attgaacgct gccgtcgtca tattgacgcc tataaagccc ctacgccagt
     6781 agacgtcatt gaaggtgata ttcgcgatat cgccattgaa aacgcatcga tggtggtgct
     6841 gaattttacc ctgcaattcc tggaaccttc cgagcgccag gcgttactgg ataaaattta
     6901 tcaagggctg aaccccggcg gcgcgctggt gctttcggaa aaattcagtt tcgaagatgc
     6961 caaagttggt gaactgttgt tcaacatgca ccacgacttt aaacgtgcca acggttacag
     7021 cgaactggag atcagccaga agcgcagcat gctggaaaac gtgatgctga ccgattccgt
     7081 ggaaacccat aaagcacgcc tgcataacgc cggttttgag catagtgagc tgtggttcca
     7141 gtgctttaac tttggttcac tggtggcatt aaaagcagag gacgctgcat gatcgacttt
     7201 ggtaactttt attctctgat tgccaaaaat catctttcac actggctcga aacgctgccc
     7261 gcgcagattg ctaactggca gcgcgagcag cagcacgggt tgtttaagca gtggtcaaat
     7321 gcggtggagt ttctacctga aattaaaccg tatcgtcttg atttattgca tagcgttacg
     7381 gcagaaagcg aagagccact gagcgcaggg caaattaaac gcattgaaac gctgatgcgc
     7441 aacctgatgc cgtggcgcaa agggccgttc tcactgtatg gcgtcaacat cgataccgaa
     7501 tggcgttccg actggaaatg ggatcgtgtt ctgccccatc tttctgattt aaccggacgc
     7561 accattctgg atgtcggctg cggcagcggt tatcacatgt ggcgcatgat tggcgcaggc
     7621 gcgcacctcg cggtggggat cgaccctacg caactgtttc tgtgccagtt tgaagcggtg
     7681 cgtaaactac tgggtaatga tcagcgcgcg catttgttac cgttaggtat tgaacaactt
     7741 ccggcactga aagcctttga taccgtcttt tcgatgggcg tgctttacca tcgccgttca
     7801 ccgctggagc atctatggca gttgaaagat caactggtca atgaaggtga actggtgctg
     7861 gaaacgctgg ttattgatgg tgatgagaac acggtgctgg taccaggcga tcgttacgcg
     7921 caaatgcgta atgtctattt catcccttcc gcgctggcgc tgaaaaactg gctgaagaag
     7981 tgtggttttg tagatatccg cattgcggat gtgagcgtta ccaccacaga agagcagcga
     8041 cgcaccgaat ggatggttac cgaatcgctg gccgatttcc tcgacccaca tgatccgggt
     8101 aaaacggtgg aaggttatcc ggcacctaaa cgcgcggtgc tgattgcgcg caagccgtaa
     8161 aggtctggta ttactgccgg atgcggcgtg aacgccttat ccggcctaca aaaccttgct
     8221 aattcaatat attgcaggga ctatgtaggc ctgataagca tagcgcatca ggcagcttta
     8281 cgtttgcata acctcagcgc ccgtttccgg gcgctattca cgtcttacgc ctgaacagct
     8341 ggctgatcaa acgccgttaa cttcggtgca ttgcccgtat atttttcgat atacaccaac
     8401 gctgagttac cggcacaggc atttgccagc tgcgagctgg ggatatccgc cgttaacacg
     8461 ttcgcactgc cgtttttaca caagccattt tccagatctg gccatgcacc ttcatgcacg
     8521 cataccacgc cttttttgat cccgtcagtc accaccgcgc ctgtcaaaat ctgaccacgt
     8581 ttgttccaga cacgcaccag atcgccattc gcaataccaa agcgtgcagc atcttcggtg
     8641 tgaatagtga ttggttcacg atcggcgatc gcatattttt tgcgcagttc cgcatagtta
     8701 agctgactgt gtaaacggtg tgccggatgt gcggtcagaa gctgtaactg cttctcgtcg
     8761 gcggtacctt tccattcatc aggagccagc caggttgggt gtgccgggca atccttatag
     8821 ccaaattttt ccaacgtttt tgaatagatt tcaattttgc cgcttggcgt acccagcgca
     8881 tttttcaccg gatcggcgcg gaaatcacca taacgaacgt actgttcgtt cttctcgctg
     8941 cggcgcattt cgatcagttt attttgctgc cagaaggcat taaacattgg catagtgacg
     9001 cgttgcgcac gggcaccttt ctgagcggca tcatagaaaa atttcagcca cgccatttca
     9061 tctttacctt cggtatagat ctcttttccg ccaggtttga gtaattccgc aagatcggca
     9121 aacacgtcaa aatcgttacg cgcttcaaat tgcggagcaa cagcctgctt catcggcaca
     9181 atatgctggt tgctgtaatc accggtcatc gtcaagtcat tgcgctcaaa cgatgtggtg
     9241 atcggtaata cgatatctgc gtgtttggct gctgcggtcc agtagcattc agaaacgacg
     9301 atcatctccg gtttctgcca tgctttaatc agacgattag tatcctggtg atgggtaaag
     9361 ttaccgccac ccgcccacca gatcattttg atattcggat acgtttgttc tttaccgtta
     9421 agctgatatt tgccgccagg attttccagc gcatcgacga tacgggcaac aggaatcgcc
     9481 gtcattccgc catcatcagc ggcctcgctg gcatgtccgg caatcgccgc agacatttcc
     9541 ggcagcacgc cgccaacacg cgtcgggttg ccaccgttgg agtaatgata agagaaacca
     9601 aaaccgccgc ccggtgtacc aatctgccct aacatcgccg ccagcgtcac cagcatccag
     9661 tgtttctgtt caccatattg ctggcgctga attccccagc ctgccatcag cattgtgcga
     9721 ttcgccgcca tcagttcagc gagtttgact atctgcgctt ccggtacgcc agtaatttcc
     9781 gccgcccaga ccgcgctctt cggcgtatta tcgctcttac ctgtcagata ctcttcaaac
     9841 tgcggatacc cggtagtgta tttttcaagg aacactttat cgtgtttgcc ttgtgtcatc
     9901 agggtatgcg caatccctaa catcagtgcc acgtcggtgc ccatattcgg cgcgatccag
     9961 gtggcattat cgtcaaagaa ttcgatggtt tcggagcgga taggatcaat ggcaatcact
    10021 ggtttgccag attttttcag ctgatggaag tattccagcc cttgctcatc ggtactgctc
    10081 caggcaattt ttaaggtatt cagcgggttc attccccaca gcaccacaac ctggctgttt
    10141 tccagaatca gcggccagga ggtctgctgt tcatacacct ctacagaacc gaccacatgc
    10201 ggcatgatca cctgtgctgc cccggttgaa taatcgccgc tatgcccgga ataaccgccc
    10261 gccaggttca tataacgttg cagtaaggtt tgcgctttat gcaacacgcc agaagagcgc
    10321 cagccgtaag atccggcaaa aatggccgat ggtccgttag ctttacgaat acgatcatgt
    10381 tgctcatgaa tcagttttaa tgcctgttcc cagctcacct gtacataggt atcttcgcca
    10441 cgacctttcg ccggttgcag tggattatcg agatagcttt ttctcaccat cggatgctga
    10501 atacgcgccg tggtgtgtac ctgatccgcc gccgtagact gtaaggaatt cggtatggtt
    10561 ttcaccagcg cgcctgttga agaaacaatc ttgccgtcct tcacttctac gttcatcgct
    10621 ccccaacgtc ccgcggtgag gattttaccg cccttctctt ctgcccatgc ggggagcggt
    10681 gctgccgatg tcaccaccag cgctccagcg gcaataccgc tgtgtttaat aaattcacgt
    10741 cttgttaatg tcataacttc ctccctgatc aacgaggatc actgtttctc ggtaatatct
    10801 ttggcgttgt actggaaata ccgcgttaaa atgtccagtt cgttttcgct catgctggtt
    10861 cgtgccccca ttcctttggc aatggacggc cacgcattga cggtgtaatg gtcggcggca
    10921 ataggggcat gacaaccagc gcaataggta tcgtcaagtt tttcagcgta ttgccatagc
    10981 ggtttacggt ccgctaatgc gggatcggta agcgcaccct gtaaagacgc ctgacgccat
    11041 tgattgccgt attcgtcagc ctgccattcc ccgtttacag tgagcgcctt gataccttct
    11101 tcacttaatg tggctagcgc cagccgttga cctgccgcca ggtagagcgt gttttcactg
    11161 ccctgcattt gataaccctg caacagaacg atcggctgtt tgccactggc atcaacgacg
    11221 gtgagatcgg ttccaggatt cacggtagcc agctcgccta tgtgagaagt tttgaaagga
    11281 taaatatgtg cgccattagt aactgaagta gcggcctgac tttccagctc atgcgccgcg
    11341 ttgtcatcca tttttatttc tggcggaaaa tgggcaatgc ctttatgaca atcgatacag
    11401 gtttcgctgt ccttttgtgc tttgttatgc attttctgcg cagattcact ttgcgaggca
    11461 atatccatgg catcaaaaga atggcaacta cggcacgttg cagagtcagt ggcttttaat
    11521 tctttccata ctgtttcggc catttcctgg cgatgagctt cgaacttatc gtcactgtct
    11581 attttgccgc taacaaattc atgataaata tctttagatg cctttaattt agcaaataaa
    11641 taatccatcc ctgactttgg aatatggcaa tcggcacatt ccgcacgtat ccctttctgg
    11701 ttcgaaaagt ggacagttcc ctgatattcc tcaaaaggtt tactcatcga gtggcaggaa
    11761 aggcaaaatg ctgtatccga cgttttatgt aaggcttttt gcgccagcaa taacccgccg
    11821 ccaccaacca caaccgctat cagcaaaaac aataacccaa tgcgtttttt ccctcgcata
    11881 gattcctcta attaaattac tggacaccga aatcattgta taattaaata tacaacgaat
    11941 taaccgcttg cataattagg cacaa
//
LOCUS       DAPHKZ010000137        11868 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.137, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000137 DAPHKZ010000000
VERSION     DAPHKZ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11868
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.137"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            2..826
                     /gene="gadX"
                     /locus_tag="RH288_003870"
     CDS             2..826
                     /gene="gadX"
                     /locus_tag="RH288_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadX"
                     /protein_id="HDV4032879.1"
                     /translation="MQSLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIRV
                     DKCVENFVFVSRDTLSLFLPMLKEEALNLHAHKKVSSLLVHHCSRDIPVFQEVAQLSQ
                     NKNLRYAEMLRKRALIFALLSVFLEDEHFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
                     LARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGY
                     HSVSYFIYVFRNYYGMTPTEYQERSAQRLSNRDSAASIVAQGNFYGTDRSAEGIRL"
     gene            1194..1922
                     /gene="gadW"
                     /locus_tag="RH288_003871"
     CDS             1194..1922
                     /gene="gadW"
                     /locus_tag="RH288_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadW"
                     /protein_id="HDV4032880.1"
                     /translation="MTHVCSVILIRRSFDIYHEQQKISLHNESILLLEKNLADDFAFC
                     SPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESG
                     VNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
                     RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYF
                     INTFRQYYGVTPHQFAQHSPGTFS"
     gene            complement(2285..5398)
                     /gene="mdtF"
                     /locus_tag="RH288_003872"
     CDS             complement(2285..5398)
                     /gene="mdtF"
                     /locus_tag="RH288_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump RND permease MdtF"
                     /protein_id="HDV4032881.1"
                     /translation="MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTIT
                     VSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDI
                     AQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
                     NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQ
                     LGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYS
                     TVARYNGKPAAGIAIKLAAGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIE
                     ISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLS
                     AVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPN
                     ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLPEED
                     QGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKDNVQSVFTVGGFGFSGQGQNNGL
                     AFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMEL
                     LDNGNLGHEKLTQARNELLSLAAQSPNQVTGVRPNGLEDTPMFKVNVNAAKAEAMGVA
                     LSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP
                     LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYS
                     WTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLAT
                     DLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPIEAIIEAARMRLRP
                     ILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHL
                     FARFKKA"
     gene            complement(5423..6580)
                     /gene="mdtE"
                     /locus_tag="RH288_003873"
     CDS             complement(5423..6580)
                     /gene="mdtE"
                     /locus_tag="RH288_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtE"
                     /protein_id="HDV4032882.1"
                     /translation="MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPG
                     SVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELN
                     SAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAV
                     EQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQD
                     FLRMKEEVASGQIKQVQGSTPVQLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIF
                     PNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIE
                     ASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ"
     gene            6640..6918
                     /locus_tag="RH288_003874"
     CDS             6640..6918
                     /locus_tag="RH288_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032883.1"
                     /translation="MRDLQTSGIVGLSASKVGYRHSDRHGEVNDKKNVAVLPTVPASI
                     RATKGSTGGYTYQGNKVVLASPLVITGGNEISICIPRHASHQFQLLMS"
     gene            complement(6919..7446)
                     /gene="gadE"
                     /locus_tag="RH288_003875"
     CDS             complement(6919..7446)
                     /gene="gadE"
                     /locus_tag="RH288_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HDV4032884.1"
                     /translation="MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVI
                     IDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEIT
                     YGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKL
                     RRMSDIVTLGITSYF"
     gene            complement(8245..8817)
                     /gene="hdeD"
                     /locus_tag="RH288_003876"
     CDS             complement(8245..8817)
                     /gene="hdeD"
                     /locus_tag="RH288_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-resistance protein HdeD"
                     /protein_id="HDV4032885.1"
                     /translation="MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFV
                     SGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPEL
                     GIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIFIAWIFLGATPMVS
                     VTLVSTLVGIELIFSAASLFSFASLFVKQQ"
     gene            9072..9404
                     /gene="hdeA"
                     /locus_tag="RH288_003877"
     CDS             9072..9404
                     /gene="hdeA"
                     /locus_tag="RH288_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeA"
                     /protein_id="HDV4032886.1"
                     /translation="MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLA
                     VDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGE
                     WDKIKKDM"
     gene            9520..9846
                     /gene="hdeB"
                     /locus_tag="RH288_003878"
     CDS             9520..9846
                     /gene="hdeB"
                     /locus_tag="RH288_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417966.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HDV4032887.1"
                     /translation="MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFID
                     LNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQA
                     SNDLPN"
     gene            9910..10557
                     /locus_tag="RH288_003879"
     CDS             9910..10557
                     /locus_tag="RH288_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDV4032888.1"
                     /translation="MTAEFIIRLILAAIACGAIGMERQMRGKGAGLRTHVLIGMGSAL
                     FMIVSKYGFADVLSLDHVGLDPSRIAAQVVTGVGFIGAGNILVRNQNIVGLTTAADIW
                     VTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNTVSML
                     DWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS"
     gene            complement(10599..11129)
                     /locus_tag="RH288_003880"
     CDS             complement(10599..11129)
                     /locus_tag="RH288_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV4032889.1"
                     /translation="MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVI
                     IDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALI
                     NGSYCSVPEAAVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNL
                     KRINELVRHQHIDYLV"
     gene            complement(11285..11851)
                     /gene="slp"
                     /locus_tag="RH288_003881"
     CDS             complement(11285..11851)
                     /gene="slp"
                     /locus_tag="RH288_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein Slp"
                     /protein_id="HDV4032890.1"
                     /translation="MNMTKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFIAVHNQ
                     PGLYVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFL
                     DPVNYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYG
                     YGAFWPEPGWGAPYYTNAVSQVTPELVK"
BASE COUNT         3253 a         2665 c         2733 g         3217 t
ORIGIN      
        1 tatgcaatca ctacatggga attgtctaat tgcgtatgca agacataaat atattctcac
       61 catggttaat ggtgaatatc gctattttaa tggcggtgac ctggtttttg cggatgcaag
      121 ccaaattcga gtagataagt gtgttgaaaa ttttgtattc gtgtcaaggg acacgctttc
      181 attatttctc ccgatgctca aggaggaggc attaaatctt catgcacata aaaaagtttc
      241 ttcattactc gttcatcact gtagtagaga tattcctgtt tttcaggaag ttgcgcaact
      301 atcgcagaat aagaatcttc gctatgcaga aatgctacgt aaaagagcat taatctttgc
      361 gttgttatct gtttttcttg aggatgagca ctttataccg ctgcttctga acgttttaca
      421 accgaacatg cgaacacgag tttgtacggt tatcaataat aatatcgccc atgagtggac
      481 actagcccga atcgccagcg agctgttgat gagtccaagt ctgttaaaga aaaaattgcg
      541 cgaagaagag acatcatatt cacagttgct tactgagtgt agaatgcaac gtgctttgca
      601 acttattgtt atacatggtt tttcaattaa gcgagttgca gtatcctgtg gatatcacag
      661 cgtgtcgtat ttcatttacg tctttcgaaa ttattatggg atgacgccca cagagtatca
      721 ggagcgatcg gcgcagagat tgtcgaaccg tgactcggcg gcaagtattg ttgcgcaagg
      781 gaatttttac ggcactgacc gttctgcgga aggaataaga ttatagagtt ttactcagac
      841 ataaaaaaaa cccggcatag gggaccggga agaggatagt ctgccgtctc cagactaata
      901 aaccgttata acactccctg ttggcacggg aaactttgtg ctctcagtaa gttaaatata
      961 acttttactg gaaataagat cagccatttt tttataaaca taagctatac gctgtgcgaa
     1021 aatatattcg tgctgcattt acttattatc aattaactgt tatgcaaaac tactttgtgg
     1081 ataaattttg gtcctaccaa atctggcagt ttttgcgcta agaaacagtc tggcatcatt
     1141 tcattagtat actgaaattg aaataatcgc agtatgaaat ataagggata atcatgactc
     1201 atgtctgctc ggtgatcctc attcgtcgtt cattcgatat ttatcatgaa cagcaaaaaa
     1261 tatcgctgca taacgagagt attctgctgc tggagaaaaa tttggcagac gattttgcgt
     1321 tttgttcacc ggatacgcga cgactggata tcgatgagct gacagtttgc cattacttac
     1381 aaaatattcg tcagctacca cgcaatttag ggttacacag caaagaccgt ttgttaatta
     1441 accagtcacc ccccatgccg ctggtgacgg cgatttttga tagcttcaat gaatccgggg
     1501 taaattcacc gatactgagc aatatgctct acctttcctg tttatcgatg ttttctcata
     1561 agaaagaact gatcccctta cttttcaata gcatcagcac tgtttcagga aaagttgaac
     1621 gccttattag ctttgatatc gccaaacgtt ggtatctgcg cgatatcgcg gaaagaatgt
     1681 ataccagcga gagtctaatc aaaaaaaagt tgcaggatga aaatacctgt ttcagtaaaa
     1741 tattactcgc ctccaggatg tcgatggcca gacgattact cgagttacgt caaattcctc
     1801 tgcatactat tgcggaaaaa tgtggctata gcagtacatc gtactttata aacacatttc
     1861 gacaatatta tggtgtaacg ccacatcagt ttgcgcaaca ttcgccaggt accttttcct
     1921 gacatatttc gcatttgaat attggtcagg atctcacacc tgcttcatgt gaaactcttc
     1981 cctgatgatt tctgccgggc taccggctag ttctctttcg cagtttgcca ggcggtatcg
     2041 gtattttcag gaggaaaaga ctcggcatgt ttgggattat taagctgaca attcatacga
     2101 ttacgggaat gtgggtcagt attgtgttgt tcaaattgat gacgaatggc tggagtggtt
     2161 tctactttca gtgctgtgta ctaagcctgg tattcctgac ggttagctgg ttgttgagtg
     2221 gtgaatggtt agcaggaaag agtaaggctg aaccttcatg ttcaacctta ctctcattta
     2281 cacgttacgc ttttttaaag cgggcaaaga gatgttccac tacaacgaaa aagaccggaa
     2341 cgaagtaaat tgccagcact gttgcggcaa acatcccgcc catcacgccg gtacctaccg
     2401 cgttttgcgc gccagaaccg gcaccatgac tgataaccag cggcagcacg ccgagaataa
     2461 aggccagaga ggtcatcagg attgggcgta aacgcatccg cgccgcttcg atgattgcct
     2521 ctatcggcgt tttcccttct ttctgcatca tctcaacggc aaattcgaca atcaggatgg
     2581 cgtttttggc ggaaagcccg atggtggtca gcaaaccaac ctggaagtag acgtcattac
     2641 ttaagccgcg cagatcggtg gccagtaatg cgccaacgac gcctaacgga acaaccaaca
     2701 tcaccgagaa cggaattgac cagctctcat agagtgcggc gagggcgagg aacaccacga
     2761 ccagtgaaat cgcatacagc gcaggagcct gatttgagga taacgcttcc tgatacgata
     2821 gtccggtcca tgagtagccg acgcctgccg gaagtttagc gaccaggtct gccataaatt
     2881 tcatggcgtc accggtactt ttcccggccg ccgcttcacc taaaatctcc attgacggga
     2941 tgccgttgta gcgttccagt cgcggtgaac cataggtcca ttcggtagac gagtaggcag
     3001 aaagcggtgc catcgtgcca gaggcgttgc gtacatacca ttggttgatg ttatccggca
     3061 acatacggaa cggcgtgcct gcctggacat acactttttt cacccgcccc tggttgagga
     3121 agtcgttcac gtagctgctg ccgaaggcgg tggaaattgt ctggttgata tcagacagcg
     3181 ccacgcccat cgcttcagct ttcgcagcgt tgacgttcac tttgaacatc ggcgtatctt
     3241 ccaggccgtt cgggcgtacc ccggtgacct gattcggtga ttgcgctgcc agtgataaca
     3301 gctcgtttcg cgcctgggtt agtttttcgt gccccaggtt accgttgtcc agcagttcca
     3361 tatcaaaacc tgacgcggta cccagttcag ccaccgcggg taagttgaac gggaagacga
     3421 cggctttatt gatactgctt aacgcaatca ttgcccgctg aatgatcgcg gtaaccgagt
     3481 tttcctcacc gacacgttca gaccacggct tgagactgat aaacgccagg ccgttgtttt
     3541 gcccctgacc gctgaagcca aagccgccaa cggtaaacac cgactggaca ttatctttct
     3601 ctttagtcag ataataatcc gtcacctgtt gcagcacttt cgtggtgtta accatggtgg
     3661 caccggaagg taactgcgcg gtggtcataa ataccccctg atcctcttct ggtaagaaag
     3721 aggtcggcgt gcgcaggaac agcaccgcca tcccggcgca aatcagcagg tagaccacca
     3781 tgtagcgacc ggtacaacgc aacagcgagc gggtgctatc ggtatagtgt tgagttgatt
     3841 tttcaaacag cgtgttgaag cgtgcgaaca gggcgttagg tttgtgaccg ccttccggcg
     3901 cggctttcag aatggtggcg cacagggcag gggtcaggct cattgccaca aatactgaaa
     3961 gcagcatgga ggagatcagc gtgatggaga actggcggta gatctccccg gttgcaccgc
     4021 tcataaaggc catcggcata aacactgcgg aaagaacaac ggcaataccg accagcgcac
     4081 gttggatctg ccccatcgat ttatgcgtcg cttccttcgg cggtagctta tcttccgcaa
     4141 tgacacgctc gacgttctcc accaccacga tggcgtcatc caccagtaac cctatcgcca
     4201 gcaccatccc gaacatagtc aacgtgttga tggtgaaacc gaccgccgac aagatcgcaa
     4261 acgtcccgag aataaccacc ggtacggcaa tcgtcgggat gattgtggca cggaaattct
     4321 gcaaaaacag atacatgacc aggaagacta ggatgatagc ctcaaccagt gttttgaaaa
     4381 cttcctgaat agaaatttcg ataaacggcg tggtgtcgta aggataaacc gtcttcagac
     4441 ttgccgggaa ataggctgat aagcggttca gttcctcttt gactgcccgc gaggtatcca
     4501 gggcgtttgc tccggcagcc agtttgatgg cgatcccggc agcaggtttg ccgttatagc
     4561 gcgccacggt ggaataatct tccgccccaa gttcgacgcg agcgacatca cgcagcagca
     4621 cttgcgaacc atcttgctga actttcaaca ggattttgcc aaattcttcc ggcgtttgca
     4681 gacgcgtctg cacaatgatc gaggcgttta gctgctggtc tgccgcctgt ggcatgccac
     4741 ccagttgacc accggaaatc tggttgtttt gcaccttaat ctgggaaata acatcggaag
     4801 gtaccaggtt atatttattg agtttttgcg ggtccagcca gatacgcatg gcatactcgg
     4861 aaccaaagag ttgtacgcta ccaacgcccg cggtacggct tagcgggtct ttgatattag
     4921 acgctacata gtccgcgata tcgtactggt tgaggctgcc gttatcagaa ataaacgccg
     4981 ctaccatcag gatattactg ctcgacttat cgacgctaat cccctgctgc tgcactgctt
     5041 caggtaatga aggcatagcg agttgcagtt tattttgcac ttgaacctgt gcgatatcag
     5101 gagatgtccc agtctcgaag gtcagagtga tagaggcatt gcccgccgca tcactggttg
     5161 aagacatgta catcaggcca tcaagcccat tcatattttg ctcaatcacc tgagtgaccg
     5221 agtcttctac cgtttgcgca tcggcacctg gataggtagc gctgacggta atggtcggtg
     5281 gcgcaatctg cggatactgc gcaaccggta agttcatgat cgccagacca cctgcaagca
     5341 tcataataat ggcaagtacc caggcaaaaa ccgggcgatc aataaaatag ttagccatga
     5401 aagtcccctt aagcctgcaa cgttattgtt tcgattcggt gctggcgttt tcctggctgg
     5461 aggaaattgc tcgtgctttg atacccggac gaatgcgttg caaaccggaa acgatcaccc
     5521 gatcgccagc ctgcaagcca gaggtgacga cccactggtc gccgatggct ttgctggctt
     5581 caatttcgcg tagctgcacg acatcgtctt tatccagaat gagcgccgtt gctttaccct
     5641 gggcgttgtg ggtgacgcct tcctgcggca ccagtaatac attctggcgg ctaccttcat
     5701 ccactaatgc cgtgacgtac atgccaggca gcaagtcacc atttgggttg gggaaaatcg
     5761 cccgtaacgt cacggagccc gtggtttcat ccactgtcgg gtcggagaat ttcagcgtgc
     5821 cggtctggct gtagcgttta ccattttcca gattgagctg tactggcgta ctgccctgaa
     5881 cctgtttgat ttgcccactg gcgacctctt ctttcatgcg taagaaatct tgcaccgact
     5941 gcgtgagatc gacataaatc gggtccagac gttgtacggt aaccagcgaa tctgcctgat
     6001 tagcggtaac gagtgcgccg acggtcaccg acgatttccc gctgacgccc gtaatcggcg
     6061 aggtgacatt cgcgtattgc agattgatcg tcgcctgttc aacagccgct ttggcgacgg
     6121 tgacattggc ttctgcttca ttcaactggg tgcgcgcggt gtcgtaatcc tgacggctaa
     6181 cgtagttggt cttcagcaac gatgcctggc ggttaaaggt gatgcgggca ttgctggcgg
     6241 tagagagcgc tttcgccagc gagcctttgg cggagtttag ctcggcctgt aaaggtgcag
     6301 gatcaatctg atacagcgaa tcgccctggt tcactttatc gccttcgata aagttgcgtt
     6361 taatgataat accgcccacc tggggacgta tctcggcaac ttcataagga acggttctac
     6421 cgggcaattc gctcaacaca ttgaccgaac cgggggagag tgtgacgaca ccgacctcag
     6481 gcgtcatggc ggcggcgttt tccgccgatt tgtcatcgca ggcggtgagc atcgcgccgc
     6541 agaataacaa cggtattaac agctttcttc ttctgttcat tttagtccct gaaaattctt
     6601 gagaaataac ggttctttaa attgcgcgcg aggagagata tgagggattt acagaccagc
     6661 ggcatagtgg ggttgtcagc cagtaaggtg ggatacaggc acagtgatcg acatggtgag
     6721 gtcaacgaca aaaaaaatgt tgccgttctg ccaacagttc ctgccagcat tcgggcaacg
     6781 aagggttcta ctggtggata cacataccag gggaataaag tcgttttagc ctctccttta
     6841 gtaatcaccg ggggtaatga aatcagcatc tgcatccctc gtcatgccag ccatcaattt
     6901 cagttgctta tgtcctgact aaaaataaga tgtgataccc agggtgacga tgtcgctcat
     6961 acgtcttagt ttcagcttgt acataatgtt gaatttctga atctttaatg tttgttgcga
     7021 aatattgagc gtcgacgtga tattgctttc atttttattt ttcagaatca gttgcataat
     7081 tttgaactga ttatgtgaaa aacataattg tgaattctta tggggcaagt gtttaccata
     7141 agtaatctca agaagatttt tgatactttc tttgcggcta acaaaataaa taggcgcttt
     7201 agcttttagt ttactgatgt gataaggtgc caaaacaata attctctcgg catctaattt
     7261 ctccagaaat ttaatcgctt cttcatcaag gatatgattg tgataggtat caatgataac
     7321 cttgaagggt ttattgccta cttttttgat ctctgacagg gaattgattt ttatcatttc
     7381 gtgattatct ttcaactgcc aaaagccctg taaaagaaaa gaatctttcg tcatgagaaa
     7441 aatcataact tgctccttag ccgttatcgt ttcgaatatg tcatcctttt cattatttac
     7501 atccttgtcc gaatcgttgt tcaatatagt aaacgcctat aagaacttta cccttcgtga
     7561 actaatacgt ctattaacac taatcaatac ttcagattta tccatcacgc actccatata
     7621 ttgatcctaa gtaagattcc tggttgttat cagcttgtaa atagcaaaca aaaagttaac
     7681 gtttgcggat tactgcccaa gaataagtta tcaataacca gtttgtgatc tctgaagaat
     7741 attactaaag ttaaaatgta atccgattta aatatcgagt ctccttgttt cgacttaagc
     7801 tggcaattgg attgccagct ttcttttaac gcattgaaat tacctgagta aataacgcat
     7861 tcatgtcttc aggtttttat atagcgtctg gagacacgga tatttatgca atgtaatcaa
     7921 cgccagttgc aaaaaaatga acccggatta cttatttaac cgcccatagc atcaacgctt
     7981 acggaactct ttgttcactt tcccacagca cttttaaaac attaaacctg actacggaaa
     8041 atatcagcca tgataatgtt tgaaatggct aatttgccat agagtgaaaa aaattagatg
     8101 aaattcagta ggttgaaata atcactagca ggtaattatt tcaatgatag tgcgcaattg
     8161 atctacaaca ctgcgtagcg gagagagtat taatcggatc atagtcacat caagtgacta
     8221 tgatccgggt gacaaccggg gtaattattg ctgcttaacg aacaaactgg cgaagctgaa
     8281 caggctggcg gcgctaaata tcagttcaat tcccaccagt gtggaaacca gcgttacaga
     8341 caccatcggc gttgcaccaa ggaatatcca ggcaatgaag atatccagca caccaataac
     8401 gagctgtagc cagctgcctt tcattgaacg ctgacgatac caactcatca ggcgaataac
     8461 ccctgcaaca cagaacaaac cggcaataaa tgccgcaatg gcaaaaatgc ccagctccgg
     8521 tgcgcggatg aagaaatagc cgatcaataa ataggcgact gcgacgagga aaccggataa
     8581 taccggccag aaattatgac tgcggttgct gaataacccg acaataagcg caatacccga
     8641 gcagattaat aatgcaccca ctactgtgct taaaatatcg ccagagacga acgggaaact
     8701 gatacacagc aacccgacga taaacagcag cacggcaata aactggattg ctctgcgatg
     8761 ttttttaagc atctccagat caaacttcaa aattgttgcc ttatctatat ataacataga
     8821 accaccctat aaaattaaga agaaaatccc ctgctatcaa tctatgccaa aaacgcgtct
     8881 aagaatgcag tcgatttaat aaaaatttcc taattgcagt atctgatgca tctgtaactc
     8941 attgtattga aataaaaata tctgattttg atattttcca tcaacatgac atatacagaa
     9001 aaccaggtta taacctcagt gtcgaaattg attcgtgacg gctctttcac tttatagttg
     9061 aggatattac gatgaaaaaa gtattaggcg ttattcttgg tggtctgctt cttctgccag
     9121 ttgtgagcaa tgcagcggat gcgcaaaaag cagctgataa caaaaaaccg gtcaactcct
     9181 ggacctgtga agatttcctg gctgtggacg aatccttcca gccaactgca gttggttttg
     9241 ctgaagcgct gaacaacaaa gataaaccag aagatgcggt tttagatgtt cagggtattg
     9301 caaccgtaac cccagctatc gttcaggctt gtactcagga taaacaagcc aactttaaag
     9361 ataaagttaa aggcgaatgg gacaaaatta agaaagatat gtaattccgg gaatgcgtta
     9421 catcgtactt ccttgcatat tgaacaggcc ggaatatctt ctttaaaagc agctattcct
     9481 cctgttcata tataatctct atattgaatg ggttacaaaa tgaatatttc atctctccgt
     9541 aaagcgttta tttttatggg cgctgtagcg gctttgtcac tggtgaacgc acaatctgcg
     9601 ctggcagcca atgaatccgc taaagatatg acctgccagg aatttattga tctgaatcca
     9661 aaagcaatga ccccggttgc atggtggatg ctgcatgaag aaacagtata taaaggtggc
     9721 gataccgtta ctttaaatga aaccgatctc actcaaattc ctaaagtgat cgaatactgt
     9781 aagaaaaacc cgcagaaaaa tttgtatacc ttcaaaaatc aagcatctaa tgacttgccg
     9841 aattaatgag gtgcaagtaa aaaggagtag caagttgagc catcttgctg ctcctttttg
     9901 catttttata tgacagcaga atttattata cgtcttatac tcgcggcaat tgcctgtggc
     9961 gctattggca tggaaaggca aatgcgcggc aaaggagcag ggttacgcac acatgtatta
    10021 attggcatgg gaagcgccct gtttatgatt gtttcgaaat atggttttgc tgacgtgctg
    10081 tctttagatc acgtcggact cgaccccagc cgtattgctg ctcaggtggt gacgggcgtc
    10141 gggtttatcg gtgcaggtaa cattctcgtt cgtaaccaaa atattgtagg tctgacgacg
    10201 gcagcggata tctgggtgac cgccgccata ggtatggtta ttggcagcgg tatgtacgaa
    10261 ctgggtattt atggttcagt gatgaccttg ttggtgctgg aagtcttcca tcaattaacc
    10321 ttccgcctga tgaacaaaaa ttaccattta cagctgacat tagtgaacgg taatacggta
    10381 tcaatgctcg actggtttaa gcagcaaaaa ataaaaactg atttagtttc gttgcaggaa
    10441 aatgaagatc atgaagtggt cgccattgat atccagcttc atgccacaac gtcgatagaa
    10501 gacctgttgc gattattaaa aggtatggca ggggtgaaag gcgtttcaat tagctaatct
    10561 gtgtggcagc gtagccagac tcaccgtaag cctgaaattc acaccagata atcaatatgc
    10621 tgatggcgta ccagctcatt gatccgctta agattgagga tcatcatgat attgtgttta
    10681 tggcagtaga acgtttttag cgatattttc agtttctcca gaatatcttc cgttgtcatt
    10741 tgattcgcaa tgcagctcag aacctgatgt tgcttgcgcg aaagtgacac agccgcttca
    10801 ggcacagagc agtaactgcc attgatgagt gcgacaaaat caatgatagt gatagtccgc
    10861 ggaacaaagg tcaccggcac tttccccagg cagcgtttaa tattaaaggg ggagaaaata
    10921 atgacatgga caggttttaa tcgttcaatt tgagtgagaa aattagaatg aaatacatta
    10981 ttcattaatg tatcaataat gacgaaggca ttctgatgca acattacgtc gatctcttct
    11041 tcgttctgta tatgaacgac attaccttta ctcagaatgt ttttcatcgc ggtgaagaac
    11101 atcgtatccc tggtaattat aagaaacata accgactcct ggtgcggaca ttaactttat
    11161 aatcagtttg ccaaaggtaa ttaacaggac agggcttata ataataatag ttagcttact
    11221 gtgtattaat ttgatgtaat gcatgatgca gatgctgaga aagcatctgc atctttcggt
    11281 ggtgttattt gaccagctca ggtgttacct gactcaccgc attggtgtag taaggcgcac
    11341 cccagcccgg ttccggccag aatgcaccat agccgtaatc ccacaggtta taggtggtat
    11401 taaccacttc tctcaaatgc cacacctgga tgccctgcat attcacttcc aggaagttat
    11461 acgggacttt attgataaag ccaggttgtt caccctgaat ggtgccgagg atggtaacaa
    11521 agtgattacg atagttcact ggatcaagga agccgctttg tctggcgagc agtcggccct
    11581 gatagttggc ttcaatatca ggcttcgcat agctatccaa cggtaataca gcgatttcta
    11641 acaacgtatc cgttttgcca ttgataacgt tgataacctt cccaccaaag cgcgcttgtt
    11701 gaccaacata taaccccggc tggttatgaa cagcaataaa acttttttga atatcaggtt
    11761 ggttattgcc tttgatattt tgcggaattg aactacatgc ggcaagcaaa aatgaaaggc
    11821 tgaggatgag tgcacctttt gtcatgttca tgttactatc cttatcaa
//
LOCUS       DAPHKZ010000138        11806 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.138, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000138 DAPHKZ010000000
VERSION     DAPHKZ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11806
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.138"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            392..1780
                     /gene="narU"
                     /locus_tag="RH288_003882"
     CDS             392..1780
                     /gene="narU"
                     /locus_tag="RH288_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter NarU"
                     /protein_id="HDV4032891.1"
                     /translation="MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLL
                     LAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRW
                     TVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK
                     QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWV
                     PLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFA
                     MLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVQVTLINFIFMAIFSALLF
                     LTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQA
                     QKEAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLT
                     WLVYGRRKFSQK"
     gene            1862..5602
                     /gene="narZ"
                     /locus_tag="RH288_003883"
     CDS             1862..5602
                     /gene="narZ"
                     /locus_tag="RH288_003883"
                     /EC_number="1.7.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase Z subunit alpha"
                     /protein_id="HDV4032892.1"
                     /translation="MSKLLDRFRYFKQKGETFADGHGQVMHSNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPLIRKRLIELWREALKQHSDPVLAWASIMNDPQKCLSYKQVRGRGGFIR
                     SNWQELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFY
                     DWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFINYCRRY
                     SDMPMLVMLEPRDDGSYVPGRMIRASDLVDGLGESNNPQWKTVAVNTAGELVVPNGSI
                     GFRWGEKGKWNLESIAAGTETELSLTLLGQHDAVAGVAFPYFGGIENPHFRSVKHNPV
                     LVRQLPVKNLTLVDGNTCPVVSVYDLVLANYGLDRGLEDENSAKDYAEIKPYTPAWGE
                     QITGVPRQYIETIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLIFCGC
                     VGQSGGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHSSQWRYEKVS
                     AQELLSPLADASKYSGHLIDFNVRAERMGWLPSAPQLGRNPLGIKAEADKAGLSPTEF
                     TAQALKSGELRMACEQPDSGSNHPRNLFVWRSNLLGSSGKGHEYMQKYLLGTESGIQG
                     KELGASDGIKPEEVEWQTAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMN
                     TSDMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQVCVGHLGKETDVVLQPLLHDS
                     PAELSQPCEVLDWRKGECDLIPGKTAPNIVAVERDYPATYERFTSLGPLMDKLGNGGK
                     GISWNTQDEIDFLGKLNYTKRDGPAQGRPLIDTAIDASEVILALAPETNGHVAVKAWQ
                     ALGEITGREHTHLALHKEDEKIRFRDIQAQPRKIISSPTWSGLESDHVSYNAGYTNVH
                     ELIPWRTLSGRQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIPPNGFPEKALNF
                     LTPHQKWGIHSTYSENLLMLTLSRGGPIVWISETDARELTIVDNDWVEVFNANGALTA
                     RAVVSQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQL
                     AWGFNYYGTVGSNRDEFIMIRKMKNVNWLDDEGRDQVQEAKK"
     gene            5599..7143
                     /gene="narH"
                     /locus_tag="RH288_003884"
     CDS             5599..7143
                     /gene="narH"
                     /locus_tag="RH288_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDV4032893.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQEEWQGGWVRDVNGKIRPRLGNKMGVITKIFANPVVPQIDDYYE
                     PFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     EAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIDAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLAN
                     MLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIA
                     NYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            7143..7838
                     /gene="narW"
                     /locus_tag="RH288_003885"
     CDS             7143..7838
                     /gene="narW"
                     /locus_tag="RH288_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDV4032894.1"
                     /translation="MQILKVIGLLMEYPDELLWECKEDALALIRRDAPMLTDFTHNLL
                     NAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLDCRE
                     LPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDALLQLAGS
                     SLSSDSVTKQVNSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDV
                     APQYVDISAGGGK"
     gene            7835..8515
                     /gene="narI"
                     /locus_tag="RH288_003886"
     CDS             7835..8515
                     /gene="narI"
                     /locus_tag="RH288_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDV4032895.1"
                     /translation="MIQYLNVFFYDIYPYICATVFFLGSWLRYDYGQYTWRASSSQML
                     DKRGMVIWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPVAAKQLMAMVLGGICGVLT
                     LIGGAGLLWRRLTNQRVRATSTTPDIIIMSILLVQCLLGLSTIPFSAQYPDGSEMMKL
                     VGWAQSIVTFRGGSSEMLNGVAFVFRLHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRSRR"
     gene            8594..9487
                     /locus_tag="RH288_003887"
     CDS             8594..9487
                     /locus_tag="RH288_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HDV4032896.1"
                     /translation="MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGH
                     SETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAHYVRAKVLGLGNCTIWQTSLAGK
                     HRVTIEKHNDDYRISLEQGTPGFELPLEGEVRAAIINALHLTEDDILPGLPIQVATTG
                     HSKVMIPLKPEVDIDALSPDLNALTAISKQIGCNGFFPFQIRPGKNETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHNVLPHDGKVLRVKGNQGRALGRDGVIEVTVTIRDNQP
                     EKVTISGAAVILFHAEWAIKL"
     gene            complement(9583..10428)
                     /gene="nhoA"
                     /locus_tag="RH288_003888"
     CDS             complement(9583..10428)
                     /gene="nhoA"
                     /locus_tag="RH288_003888"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HDV4032897.1"
                     /translation="MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVL
                     LPREIQLDNQSLEEKLVIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPAL
                     PPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVPDLVQTTPHGEYRLLQEGDDWVL
                     QFNHHQHWQPMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLT
                     NFHFTHYENGHAVEQRNLPDVASLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTH
                     PEAGK"
     gene            10601..11170
                     /locus_tag="RH288_003889"
     CDS             10601..11170
                     /locus_tag="RH288_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDV4032898.1"
                     /translation="MSRFIPIELHHASRLLNHGPTVLITSFDEQSQRRNIMAAAWSMP
                     VEFEPPRVAIVVDKSTWTRELIEHNGKFGIVIPGVAATNWTWAVGSVSGRDEDKFNCY
                     GIPVVRGPVFGLPLVEEKCLAWMECRLLPATSAQEEYDTLFGEVVSAAADARVFVEGR
                     WQFDDDKLNTLHHLGAGTFVTSGKRVTAG"
     gene            complement(11167..11400)
                     /gene="pptA"
                     /locus_tag="RH288_003890"
     CDS             complement(11167..11400)
                     /gene="pptA"
                     /locus_tag="RH288_003890"
                     /EC_number="5.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tautomerase PptA"
                     /protein_id="HDV4032899.1"
                     /translation="MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIAL
                     QQIQPESWQAIWDAEIAPQMEALIKKPGYSMNA"
     gene            complement(11500..>11806)
                     /locus_tag="RH288_003891"
     CDS             complement(11500..>11806)
                     /locus_tag="RH288_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HDV4032900.1"
                     /translation="EMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVMNEDD
                     CKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLTGSGLS"
BASE COUNT         2763 a         3054 c         3109 g         2880 t
ORIGIN      
        1 aggcaataag agaggaaccg atagaccttc tggacagatc gttttcctcc agttcatggc
       61 ctttttagtg aataaatcat cactaattct ataagtgtct ggtcttgttg ataatatagt
      121 taatatgtaa ccctttagat tcacgatctg aagggttgaa acatgacata cgttcaaaga
      181 ttaaccccgt ttgaaggtta gcttgttagt tacatttagt aacacatatc tggctactta
      241 atccccattc tgcccccgcg gttacgcttt cttatctatt ctttcaatca gcacttcacc
      301 caattcatcc ttaattctaa taactggcta ttgcgcctta cctcgtgttt tgtctttttt
      361 tcattaccaa tgtgtgcatg tgaggaacaa tatggcactg caaaatgaga aaaatagtcg
      421 ttatcttttg cgcgactgga aaccagaaaa tccggccttc tgggaaaata aaggaaaaca
      481 tattgctcga agaaatctct ggatatcagt cagttgtcta cttcttgcct tctgtgtctg
      541 gatgctattt agcgcagtta ccgttaatct caataaaatc ggttttaatt ttactaccga
      601 tcaactcttt ttattaaccg cattaccctc cgtttctggc gcattattgc gtgttcccta
      661 ctcctttatg gtgcctatat tcggtggacg ccgatggacg gtttttagta ctgcaatcct
      721 gattattcct tgcgtctggc tcggaattgc cgtgcaaaat ccgaatactc cttttgggat
      781 atttatcgtt atcgctttgc tatgcggttt tgcaggtgca aactttgctt cgagcatggg
      841 caatatcagt ttcttctttc caaaagccaa acaagggagc gctcttggga ttaatggcgg
      901 attaggaaac ttaggtgtaa gtgtaatgca gctggttgca ccgctggtca tttttgtacc
      961 tgtatttgcc tttctcggcg tcaatggcgt accgcaggcc gacggttcgg tgatgtcgct
     1021 ggcgaatgcc gcatggattt gggtaccgct actggcgatt gccacgatcg ccgcctggtc
     1081 agggatgaat gatatcgcca gttcacgcgc ctcaattgcc gaccagctcc ctgtcttaca
     1141 acgcctgcat ctctggctgc tgagcctgct ttaccttgcc accttcggtt cgtttatcgg
     1201 tttttctgcg ggttttgcca tgctggcaaa aacccagttc ccggatgtga atattctgcg
     1261 cctggcgttc tttggcccat ttatcggtgc catcgcgcgg tcggttggtg gtgctatttc
     1321 cgataagttc ggcggcgtgc aggtgacgtt gatcaacttt atttttatgg cgattttcag
     1381 tgccctgctg ttccttacct tgccgggcac aggctccggt aatttcatcg ccttttacgc
     1441 cgtatttatg gggctgtttc tgactgcggg tctgggaagt ggttctactt tccagatgat
     1501 cgccgtcatc tttcgccaga taaccattta tcgggtaaag atgaaaggcg gtagtgatga
     1561 gcaagctcag aaagaagccg tcaccgaaac ggcggcggct ctgggcttta tctcagccat
     1621 tggcgcagtg ggcggctttt ttattccgca ggcgtttggc atgtcgctca atatgaccgg
     1681 ctctccggtc ggcgcgatga aagtgttttt aatcttctac atcgtttgtg tgctgctgac
     1741 ctggctggtt tatggtcggc ggaagttcag ccaaaaataa gagatcgatg cctgatgtac
     1801 aaccgtgtcg catccgacaa ggcatcagat cccaattcat tcctggagca ggagtcatgt
     1861 catgagtaaa cttttggatc gctttcgcta cttcaaacaa aagggcgaaa cctttgccga
     1921 tggtcacgga caggtgatgc atagcaaccg cgactgggag gacagctatc gccagcgttg
     1981 gcagttcgac aaaatcgtgc gttccaccca cggtgttaac tgtacaggct cctgtagctg
     2041 gaaaatctac gttaaaaatg gtctggtgac ctgggaaatc caacagaccg actacccgcg
     2101 cactcgccct gacctgccca atcatgaacc tcgcggctgc ccgcgtggcg caagttactc
     2161 ctggtatctt tacagcgcta accgcctgaa atacccgctc attcgtaaac gactgattga
     2221 actgtggcgc gaagccctca agcaacacag cgatccggta ctggcgtggg catcgattat
     2281 gaacgatccg caaaagtgcc tgagctacaa acaagtgcgt gggcgcggcg ggtttatccg
     2341 ctccaactgg caggaactaa accagctgat tgccgccgct aacgtctgga ccatcaaaac
     2401 ctacggcccg gatcgcgttg ccggtttctc gccgatcccg gcgatgtcga tggtttctta
     2461 cgccgccgga acgcgttatc tgtcgctgct tggcggcacc tgtttaagtt tctacgactg
     2521 gtattgcgac ctgccgcccg cctcgccgat gacctggggc gagcaaaccg acgtaccgga
     2581 atctgccgac tggtataact ccagctacat catcgcctgg gggtctaacg taccgcagac
     2641 acgtacgccg gacgcccact tctttaccga agtacgctac aaaggcacta aaaccatcgc
     2701 cattacccct gactactctg aagtggccaa attgtgcgac cagtggctgg caccgaaaca
     2761 aggcactgat agcgccctgg cgatggcaat gggccatgtg attttaaaag agtttcatct
     2821 cgataatccc agcgactact ttatcaacta ctgccgccgc tacagcgaca tgccgatgct
     2881 ggtaatgctg gagcctcgcg acgatggtag ctacgttccc gggcgcatga tccgcgcatc
     2941 tgacctggtg gatggactgg gcgaaagcaa caatccgcag tggaaaaccg tagcagttaa
     3001 taccgcaggt gaattggtag tgccgaacgg ttcgattggt ttccgctggg gagaaaaagg
     3061 caaatggaat ctggaatcca ttgccgccgg tacggaaacc gaattgtcgt taaccctgct
     3121 cggtcaacat gacgctgttg caggcgtggc cttcccctac tttggcggca ttgaaaatcc
     3181 gcattttcgc agcgtaaaac acaatccggt gctggtgcgc caattgcccg ttaaaaacct
     3241 gacgttagtc gatggcaaca cctgtccggt ggtcagcgtt tatgatttgg tactggcgaa
     3301 ttacggcctc gatcgcgggc tggaagatga aaacagtgcg aaagattacg ctgaaatcaa
     3361 accgtacacc ccagcctggg gtgagcaaat taccggcgtg ccgcgccagt atattgaaac
     3421 catcgctcgt gaatttgccg atactgccca taaaacgcat gggcgctcaa tgattatcct
     3481 cggtgctggc gtcaaccact ggtatcacat ggatatgaac taccgtggga tgatcaatat
     3541 gctgatcttc tgcggttgtg tcgggcaaag cggcggcggc tgggcgcatt atgtcggtca
     3601 ggaaaaactg cgcccacaaa ccggctggtt gccgctggcc tttgcgctcg actggaaccg
     3661 cccaccgcgc cagatgaaca gtacctcgtt tttctacaat cattccagcc aatggcgcta
     3721 tgaaaaagtc tctgcgcagg agttactttc accgctcgcc gatgccagta agtacagcgg
     3781 tcatctgatt gatttcaacg ttcgcgccga acgtatgggc tggctacctt ctgcgccgca
     3841 gctggggcgt aacccgctcg ggattaaagc tgaagccgac aaggccggat tatcccccac
     3901 agaatttacc gcccaggcgc tgaaatcggg cgagttgcgt atggcctgcg aacaaccaga
     3961 tagcggcagc aatcatccgc gtaatttgtt tgtctggcgt tctaacctgc ttggctcctc
     4021 cggcaaaggc cacgagtata tgcagaagta tctgctgggg accgaaagcg ggattcaggg
     4081 caaggaactc ggtgccagcg acgggatcaa accggaagaa gtcgagtggc aaactgcggc
     4141 gattgaaggc aagctcgacc tgctggtgac gctcgacttc cgcatgtcca gtacctgcct
     4201 gttctccgat atcgttctgc ccaccgccac ctggtatgaa aaagacgata tgaacacctc
     4261 ggatatgcat ccgtttattc atccgctttc tgcggcggtc gatccggcct gggagtcacg
     4321 cagcgactgg gaaatctaca aaggtattgc caaagcattt tcgcaagtgt gcgtgggtca
     4381 tcttggcaaa gaaaccgatg tggtattaca accactgctg cacgactctc cggcagagct
     4441 ctcacagccg tgtgaagtgc tcgactggcg caaaggcgaa tgcgatctga ttccaggtaa
     4501 aaccgcgccg aatattgtgg cggtggagcg cgactaccct gctacgtatg aacgctttac
     4561 ctcgctcggg ccattgatgg acaaacttgg caacggcggt aaagggattt cgtggaatac
     4621 gcaggatgaa atcgatttcc tcggtaaact caattacacc aagcgtgatg gcccagcgca
     4681 ggggcgtccg ctgattgaca ccgccattga cgcttcagaa gtgattctgg cactggcacc
     4741 agaaaccaac ggtcatgttg cagttaaagc gtggcaggcg ctgggcgaga tcaccgggcg
     4801 cgaacatacc catctggcgc tgcacaaaga ggacgagaag attcgctttc gcgatattca
     4861 ggcgcagccg cgtaaaatta tctccagccc cacctggtcc ggtctggaaa gcgatcacgt
     4921 atcctataac gcgggataca ccaacgttca tgagttaatt ccgtggcgca cgctgtcggg
     4981 acgccagcag ctctatcagg atcatccgtg gatgcgtgct tttggtgaaa gcctggtggc
     5041 ttatcgcccg cctatcgaca cccgtagcgt cagtgagatg cgccagatac cgccaaacgg
     5101 cttcccggaa aaagcactta acttcctgac gccgcaccag aaatggggca ttcactcaac
     5161 ctacagtgaa aacctgctaa tgctgacgct ctctcgcggt ggaccgattg tctggatcag
     5221 cgaaacagat gcccgagaac tgaccattgt cgataacgac tgggtggaag tattcaacgc
     5281 caacggcgcg ctgactgccc gcgcggtggt cagccaacgt gtaccgccgg gcatgaccat
     5341 gatgtatcac gcccaggaac gcattatgaa tattcctggt tcggaagtaa ctggcatgcg
     5401 cggcggcatt cataactcgg tcacccgcgt ttgcccgaaa ccgacgcata tgattggcgg
     5461 ttacgcgcag ctggcctggg gctttaacta ctacggcacc gtcggctcga accgcgacga
     5521 attcatcatg atccgcaaga tgaagaacgt taactggctg gatgatgaag gtcgcgatca
     5581 ggtacaggag gcgaaaaaat gaaaatccgt tcgcaagtcg gcatggtgct taatctcgat
     5641 aaatgtatcg gctgccatac ctgttcggtg acctgtaaaa acgtctggac cggacgcgaa
     5701 ggcatggagt acgcatggtt taacaacgtc gaaaccaaac cgggcattgg ttatccgaaa
     5761 aactgggaag atcaggaaga gtggcaaggc ggctgggtgc gtgatgtgaa tggcaagata
     5821 cgcccgcgtc tgggcaacaa gatgggcgta ataaccaaaa tcttcgccaa cccggtggtg
     5881 ccgcagattg atgattacta cgaacctttc accttcgact acgaacattt gcatagcgca
     5941 ccggaaggca aacatattcc tactgctcgc ccgcgttcac tgattgacgg caaacggatg
     6001 gacaaagtga tctgggggcc aaactgggaa gaactgctgg gcggtgagtt cgaaaaacgt
     6061 gcccgcgacc gcaacttcga ggccatgcaa aaggagatgt acgggcagtt tgaaaacacc
     6121 ttcatgatgt acctgccgcg cctgtgcgaa cactgcctca atcccagctg cgtggcgacc
     6181 tgcccaagcg gcgctatcta caaacgcgaa gaagacggca ttgtgctgat tgatcaggat
     6241 aaatgccgtg gctggcgttt gtgcataagc ggttgtccgt acaaaaaaat ctacttcaac
     6301 tggaaaagcg gcaagtcaga aaaatgcatc ttctgttacc cacgaattga gtccggtcaa
     6361 ccgaccgtgt gctcagaaac ctgcgtgggt cgcatccggt atctgggcgt gctgctttac
     6421 gacgccgacc gcatcgagga agcggcgagc accgagcgcg aagttgacct ctatgaacgc
     6481 cagtgcgaag tgttcctcga tccacacgat ccctcagtga tcgaggaagc cctgaaacaa
     6541 ggtattccac aaaatgtgat tgacgctgcc cagcgttcgc cagtctacaa aatggcgatg
     6601 gactggaaac tggcactacc gttgcaccct gaataccgca ccctgccgat ggtctggtac
     6661 gttcctccgc tgtcaccgat tcagtcctac gcagatgcgg gcggtttgcc gaaaagcgaa
     6721 ggcgtgctgc ccgccatcga aagcctgcgt attccggtgc aatatctcgc caatatgttg
     6781 agtgccggcg ataccggtcc ggtactgcgg gcgctgaaac ggatgatggc gatgcgccac
     6841 tatatgcgtt cacaaaccgt ggaaggcgtt actgatactc gtgccatcga cgaagtaggc
     6901 ctgagcgtcg cccaggtcga agagatgtat cgctatctcg ccattgccaa ctatgaagat
     6961 cgttttgtta tcccgaccag ccatcgggaa atggcgggcg atgccttcgc agaacgcaac
     7021 ggctgcggtt ttacctttgg cgacggttgc cacggttcgg acagtaaatt caacctgttc
     7081 aacagtagcc gtatcgatgc catcaacatc accgaagtgc gcgacaaagc ggagggcgaa
     7141 taatgcagat cctcaaagtg atcggcctgt tgatggagta tccggacgag ctgttgtggg
     7201 aatgcaagga ggacgcgctg gcgttgatcc gccgcgacgc gccgatgctt acggatttca
     7261 cccacaacct gcttaacgcg ccgctgctgg ataaacaggc cgaatggtgc gaagtgtttg
     7321 accgtggacg taccacatcg ctgctgctgt tcgaacatgt tcatgccgag tcccgcgatc
     7381 gcggccaggc aatggtggac ctgctggcgg agtatgaaaa ggtcggcctg caactggatt
     7441 gtcgggaact gcccgattat ctaccgctgt atctggagta tttaagcgta ctgcctgacg
     7501 atcaggcgaa agaaggattg ctcaatgttg cgccgatcct cgccctgctt ggcggtcgct
     7561 taaaacaacg cgaggcaccg tggtacgcgt tgtttgatgc tctgctgcaa ctggcgggaa
     7621 gctccctttc aagtgacagt gtcacaaaac aagtaaacag cgaagagcgc gatgacaccc
     7681 gccaggcgct tgatgcagtg tgggaagagg aacaggtgaa gtttattgaa gataacgcca
     7741 cggcgtgtga cagctcgccg cttaatcaat atcagcgacg ctttagccag gatgtcgcgc
     7801 cgcaatatgt cgacatcagt gcgggaggtg ggaaatgatt cagtatctga acgtcttttt
     7861 ttacgatatc tacccgtaca tttgtgcgac ggtgtttttc ctcggcagct ggctgcgcta
     7921 cgactacggg cagtacacct ggcgcgcctc ctcaagtcaa atgctcgata aacgcgggat
     7981 ggtgatatgg tcgaatctgt tccatatcgg cattttgggg attttcttcg ggcacttgtt
     8041 cggcatgtta acgccgcact ggatgtacgc gtggtttttg ccagtggcag cgaaacaact
     8101 catggcgatg gtgctcggcg gtatttgcgg tgtgttgacg ttgattggcg gcgcaggact
     8161 gctgtggcgc aggctgacaa atcagcgcgt gcgtgccact tccactacgc cggatatcat
     8221 catcatgagc attttgctgg tccagtgtct gttggggcta agtaccatac cgttttcagc
     8281 acagtatcct gatggtagcg aaatgatgaa gctggtgggt tgggcgcaaa gcattgtcac
     8341 tttccgtggt ggatcgtcag agatgctcaa cggcgtagcg ttcgtcttcc gcctgcatct
     8401 ggtgttggga atgaccatct tcctgctctt cccgttcacc cgactggtgc atgtgtggag
     8461 cgcgccgttt gagtacttta ctcgtcgata tcaaattgtg cgttcgcggc gataatttca
     8521 ccctggccgg atagcccttc gctctccggc cacttgcagg ctatgatagt tctccagtca
     8581 caggagaacg ttaatgaaac cgcaggtgta ccacgtcgat gcttttacct cacaaccgtt
     8641 tcgcggcaat tctgccggtg ttgttttccc cgccgataat cttagcgaag cgcaaatgca
     8701 gcttatcgcc cgcgagttag gccattcgga aactgctttt ctgctgcaca gcgacgacag
     8761 cgatgtgcgc atccgctact ttacgccaac ggttgaagtg ccgatttgcg gtcatgcgac
     8821 agtagctgcg cactatgtac gtgcgaaggt gttaggttta ggaaattgca cgatctggca
     8881 aacatcgctg gcaggaaaac atcgcgtgac tatcgaaaag cacaacgatg attatcgtat
     8941 ttcgctggaa caaggtacgc cgggctttga actgccgctg gagggtgaag tacgcgcggc
     9001 gattatcaac gcattgcatc ttactgaaga cgatattctg ccgggtttgc cgatccaggt
     9061 cgcgacgacc gggcattcta aagtgatgat cccattgaag ccggaagtgg atatcgacgc
     9121 tctttcgcct gaccttaatg cgctgaccgc tatcagtaaa cagattggct gcaatggttt
     9181 cttcccgttc cagatccgtc caggcaaaaa cgaaaccgat ggtcgtatgt tctcgcctgc
     9241 gattggtatt gtggaagatc cggtgactgg caatgccaat ggcccgatgg gtgcatggtt
     9301 ggtacatcac aacgtattgc cccacgatgg caaggtgctg cgtgttaaag gcaatcaggg
     9361 gcgcgcattg gggcgtgacg gcgtgattga agtgacggtg acaattcgtg ataaccaacc
     9421 ggaaaaagtc accatttctg gcgcggcggt gattttgttt catgccgaat gggcaattaa
     9481 actctgaaac cgttgcctga tgcgcttcgc ttatcaggtc tacaaccggg ttaatgtatg
     9541 ccggataagg cgtttacgcc gcatccggca acctgacata aattattttc ccgcctccgg
     9601 atgcgtatca aacgccgcca tcaccagcgc taactcatcc acagtaaagc catgtttcgc
     9661 atcatccacg cccagaccaa actgttcctg catcacggca tataacgacg ccacatccgg
     9721 tagatttcgc tgctccaccg cgtgcccatt ttcataatgg gtaaaatgaa aattggtcag
     9781 tgtcagcttg ccgccgtccg gcaaatggcg gcacatcagc aaatgatggc gaaaatgcga
     9841 ctgcggccag tgcgccgacc agaaattgcc catcacataa tcgctttgtt gctgctcgca
     9901 gagatcgaag cggtacatcg gctgccaatg ctgatgatga ttaaactgca acacccaatc
     9961 atcaccctcc tgcaacaacc gatactctcc gtgtggcgtg gtctgcacga gatcgggaac
    10021 taaacgaatc ggcgcggtta gcgtctgccc accgaaaccg acatcagcaa tccatttttc
    10081 ctcttccagt tccaccaaca gcaaacgatg ggtgcgcggc ggtaatgctg gcggatttga
    10141 taacactacg cgccctaaca agctgcgaac gttaaacccc agctcgcgta acacccgctc
    10201 aaacacgcca ttctgctcaa aacagtaacc gccacgacgg gctatcacca gtttctcttc
    10261 cagcgattga ttatcaagct gtatttccct cggcagcaaa acgtcgaggt tttcaaacgg
    10321 aatggtgcaa ttgtgtttca ggtgcaatgc acgaagcgta tcaatattga ccgcagcagc
    10381 tcccgaccag ttaatacggg caaaatagtg attcagaatg ggcgtcatca ggcgtttccc
    10441 ttagtggttt tctcaactta taacctggaa tagacgccgc accggctatt ttgtgcgatc
    10501 gcggacatgc atcacgttcg caaatcgcca atcccgttaa tttcgttact tattgcgtta
    10561 cggactacgc ttaaaaaaac cttcttcgcg aggcgatacc atgagccgat tcatccccat
    10621 agaattacac catgccagcc gtctgttaaa tcatggccca acggtcttga tcaccagttt
    10681 cgatgagcaa tcccagcggc gtaacattat ggctgcagcc tggtcaatgc cggtggagtt
    10741 tgaacctcca cgcgtggcga ttgtggtaga taaatcgaca tggaccaggg agttgattga
    10801 acataacggt aaatttggca tcgttatccc gggcgttgca gcaactaact ggacgtgggc
    10861 ggtgggaagt gtgtcggggc gtgatgaaga taaatttaat tgctatggca ttccggttgt
    10921 gagaggcccg gtatttggtt tgcctctggt cgaggaaaaa tgtctggcgt ggatggagtg
    10981 tcgattgcta cctgcgactt ctgcgcaaga agaatacgac acgctgtttg gcgaagtagt
    11041 atcagcagcg gcagacgcac gggtatttgt cgaaggccgc tggcagtttg atgatgataa
    11101 gctcaatacg ttgcatcatt taggtgctgg gacgtttgtt accagcggca agcgtgttac
    11161 ggcgggttaa gcattcatgc tataaccagg tttctttatc aaagcctcca tttggggcgc
    11221 gatttcggca tcccagatag cttgccaaga ttctggttga atctgctgta gagcaatgct
    11281 tatcgaactg tctttactgt tcagatgacg aataataacg tcggtaatat ctgcagcaag
    11341 tgctgctttt tgttgttcgt ccagttcacg cggaaaacat ttaatgtcga tgtgcggcat
    11401 gattacgctc cttttgaaag atgtcagtaa aattaacaca cattgtgaat gtcatgtgtc
    11461 cggtaaagcg tttatacgac aataatgccc agggcaagat tacgaaagcc cgctccccgt
    11521 aaggactgac gccaggtagt ttctgtccat ggctgctttt cgcatcttac gtcttaaccc
    11581 tgccttgaat accttatcat tcgtcaaaat attaatagca atgtgccgta tccctgaaaa
    11641 taattctgct gcatttcctc ttcttatttt gcagtcgtct tcattcatta ccacgtccag
    11701 acgccagtgc agcttattct ccacatgcca gtggtttcgg attgctgtgg cgaacttctc
    11761 tgcggttaaa tcagcagaac tgatataata tctgaccgtc atttcg
//
LOCUS       DAPHKZ010000139        11798 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.139, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000139 DAPHKZ010000000
VERSION     DAPHKZ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11798
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.139"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            56..553
                     /gene="ftnA"
                     /locus_tag="RH288_003892"
     CDS             56..553
                     /gene="ftnA"
                     /locus_tag="RH288_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HDV4032901.1"
                     /translation="MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKIN
                     ELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELST
                     LDTQN"
     gene            complement(591..830)
                     /locus_tag="RH288_003893"
     CDS             complement(591..830)
                     /locus_tag="RH288_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HDV4032902.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSA
                     EGMTAGELVAFLAAKGKFIPSKDGFSTDQSKICRH"
     gene            1021..2232
                     /gene="tyrP"
                     /locus_tag="RH288_003894"
     CDS             1021..2232
                     /gene="tyrP"
                     /locus_tag="RH288_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HDV4032903.1"
                     /translation="MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
                     LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNIRKLRWVF
                     IIGSAIPLVAYIFWQVATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQF
                     LIAAGLLPEVG"
     gene            complement(2294..2959)
                     /gene="yecA"
                     /locus_tag="RH288_003895"
     CDS             complement(2294..2959)
                     /gene="yecA"
                     /locus_tag="RH288_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YecA"
                     /protein_id="HDV4032904.1"
                     /translation="MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSP
                     QEIEPEQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFG
                     LREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
                     PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(3155..3241)
                     /locus_tag="RH288_003896"
     tRNA            complement(3155..3241)
                     /locus_tag="RH288_003896"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3205..3207),aa:Leu,seq:taa)
     gene            complement(3254..3327)
                     /locus_tag="RH288_003897"
     tRNA            complement(3254..3327)
                     /locus_tag="RH288_003897"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3293..3295),aa:Cys,seq:gca)
     gene            complement(3382..3457)
                     /locus_tag="RH288_003898"
     tRNA            complement(3382..3457)
                     /locus_tag="RH288_003898"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3422..3424),aa:Gly,seq:gcc)
     gene            complement(3609..4157)
                     /gene="pgsA"
                     /locus_tag="RH288_003899"
     CDS             complement(3609..4157)
                     /gene="pgsA"
                     /locus_tag="RH288_003899"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDV4032905.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAV
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARADLLDQ"
     gene            complement(4214..6046)
                     /gene="uvrC"
                     /locus_tag="RH288_003900"
     CDS             complement(4214..6046)
                     /gene="uvrC"
                     /locus_tag="RH288_003900"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDV4032906.1"
                     /translation="MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETAS
                     QNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEV
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY
                     GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(6043..6699)
                     /gene="uvrY"
                     /locus_tag="RH288_003901"
     CDS             complement(6043..6699)
                     /gene="uvrY"
                     /locus_tag="RH288_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HDV4032907.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCR
                     TNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
                     "
     gene            6995..7171
                     /locus_tag="RH288_003902"
     CDS             6995..7171
                     /locus_tag="RH288_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032908.1"
                     /translation="MIKIFIGHYINAFNSTVDDTLKKQPLLFLAKLMVYSAALTFFTA
                     NFHCNMTRKINEYA"
     gene            7158..7382
                     /locus_tag="RH288_003903"
     CDS             7158..7382
                     /locus_tag="RH288_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HDV4032909.1"
                     /translation="MSTPDFSTAENNQELANEVSCLKAMLTLMLQAMGQADAGRVMLK
                     MEKQLALIEDETQAAVFSKTVKQIKQAYRQ"
     gene            complement(7450..8172)
                     /gene="sdiA"
                     /locus_tag="RH288_003904"
     CDS             complement(7450..8172)
                     /gene="sdiA"
                     /locus_tag="RH288_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HDV4032910.1"
                     /translation="MQDTDFFSWRRTMLLRFQRMEAAEEVYHEIELQAQQLEYDYYSL
                     CVRHPVPFTRPKVAFYTNYPEAWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSE
                     AQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRSSAREIPILSDELQLKMQLLVRE
                     SLMALMRLNDEIVMTPEMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQKNM
                     QKKINAPNKTQVACYAAATGLI"
     gene            complement(8402..9154)
                     /gene="yecC"
                     /locus_tag="RH288_003905"
     CDS             complement(8402..9154)
                     /gene="yecC"
                     /locus_tag="RH288_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HDV4032911.1"
                     /translation="MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTV
                     LENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMD
                     QGRIVEQGAAKALFADPQQPRTRQFLEKFLLQ"
     gene            complement(9151..9819)
                     /gene="tcyL"
                     /locus_tag="RH288_003906"
     CDS             complement(9151..9819)
                     /gene="tcyL"
                     /locus_tag="RH288_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HDV4032912.1"
                     /translation="MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMR
                     LSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAY
                     AAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQE
                     REPK"
     gene            complement(9834..10820)
                     /gene="dcyD"
                     /locus_tag="RH288_003907"
     CDS             complement(9834..10820)
                     /gene="dcyD"
                     /locus_tag="RH288_003907"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416429.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HDV4032913.1"
                     /translation="MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTP
                     MAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
                     SNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGV
                     TVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLA
                     RLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV"
     gene            complement(10925..11725)
                     /gene="tcyJ"
                     /locus_tag="RH288_003908"
     CDS             complement(10925..11725)
                     /gene="tcyJ"
                     /locus_tag="RH288_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV4032914.1"
                     /translation="MKLAHLGRQALMGVMAVALVAGMSVKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRID
                     VVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTIKTAADLKGKKVGVGLGTNY
                     EEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEA
                     FSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK"
BASE COUNT         2900 a         3099 c         2767 g         3032 t
ORIGIN      
        1 ataacaaatt atagtgacgc cacagcaaca aatataacct ttgtggagca ctatcatgct
       61 gaaaccagaa atgattgaaa aacttaatga gcagatgaac ctggaactgt actcttcact
      121 gctttatcag caaatgagcg cctggtgcag ctatcatacc ttcgaaggtg ctgccgcgtt
      181 cctgcgccgt cacgcccagg aagagatgac gcatatgcag cgtctgtttg attacctgac
      241 tgataccggc aatttaccgc gtattaatac cgttgaatct ccgtttgctg aatattcctc
      301 acttgatgaa ttattccagg aaacctataa acacgaacaa ttaatcaccc agaaaattaa
      361 cgaactggct catgctgcaa tgaccaatca ggactaccca acatttaatt tcctgcaatg
      421 gtatgtttct gagcagcatg aagaagagaa actgttcaaa tcgattattg ataaattaag
      481 cctggcaggc aaaagcggcg aaggtctgta ttttatcgac aaagaactct ctaccctcga
      541 cacacaaaac taatgctctc cggcggcagg tttactgccg ccgtttcaaa tcagtgacgg
      601 caaatcttac tctgatcggt cgaaaaaccg tctttcgaag gtataaattt gccttttgct
      661 gccagaaacg ctaccagctc tcccgctgtc atcccttctg ccgagcaggt gtgaaaacgt
      721 gcctgttcac caaaacgcgc tttaatcgca gcttccagac tggcatgcgt atattgctcg
      781 cctgattcaa tcatcatatt taacacttca tgaccgtgaa tagagtccat cgtccctcct
      841 caaaaaaagc ctagcgtagc gattgccgct tatgaagact ttgcgccagc gcaggactga
      901 atgcttttta ttgtacattt atatttacac catatgtaac gtcggtttga cgaagcagcc
      961 gttatgcctt aacctgcgcc gcagatatca ctcataaaga tcgtcaggac agaagaaagc
     1021 gtgaaaaaca gaaccctggg aagtgttttt atcgtggcgg gaaccacaat tggcgcaggc
     1081 atgctggcaa tgccgctggc tgcggccggt gttggtttta gcgttacgtt aatcttgttg
     1141 attgggcttt gggcgttgat gtgctacacg gcgctattac tgctggaggt gtaccagcat
     1201 gttccggcag ataccggtct gggcacgctg gcaaaacgct atctgggacg ctacggtcaa
     1261 tggctgacgg gcttcagtat gatgttctta atgtatgctc tgactgcggc atacatcagc
     1321 ggtgccggtg aattgttggc ctccagcatc agcgactgga caggtatttc tatgtcggca
     1381 accgctggcg tgctgttgtt cacttttgtt gccggtggcg tggtttgtgt cggaacttca
     1441 ctggtcgatt tatttaaccg ttttctgttc agcgccaaga ttatttttct ggtggtaatg
     1501 ctggtactac tgctgccgca tattcacaaa gtgaatcttt taaccctgcc gttgcaacag
     1561 gggctggctc tgtctgcaat cccggtgatt tttacgtcgt ttggttttca cggtagcgtg
     1621 ccgagtattg tcagctatat ggatggcaac attcgtaagc tacgctgggt gtttataatc
     1681 ggtagtgcga tccccctggt ggcatatatt ttctggcagg tggcgacgct tggcagcatt
     1741 gattcaacaa cctttatggg attgctggct aatcatgctg gattaaacgg gctgttacag
     1801 gcgttacgcg aaatggtggc ctctccgcat gttgagctgg cagtgcattt atttgctgat
     1861 ttagccctcg ccacgtcatt tctcggcgtt gcgttaggct tatttgatta tctggctgat
     1921 ttatttcagc gttcaaatac cgttggtgga cggttgcaaa ctggtgcaat tacgtttctg
     1981 ccgccgttgg cgtttgcact gttttatcca cgaggatttg tgatggcgct gggttacgcc
     2041 ggtgtggcgc tggcggtact ggcattgatt atcccttcgc tgttgacctg gcaaagcaga
     2101 aagcacaatc ctcaggcggg ttaccgggtc aaaggtggtc gtccggcgct ggtggtggtg
     2161 tttctctgtg gtattgctgt gattggcgtg caatttttga ttgcggcagg gttgttacca
     2221 gaagtggggt gatcagatag cctcaaattc cttattgggt gccagaatta acgctgacac
     2281 ccaatttggc ctcttaatgc aggcagcact gcttaaattt cttaccacta ccgcacgggc
     2341 aaggatcgtt acgccccggt ttctcttctg ctttgatcgg ttgctgaaca gctttttcct
     2401 gcggatgcgc catccagtac gcatgtagat caagcgccgc cagtcgaatg gcatctacgc
     2461 tctcttcaaa cgcttctggc gacatctttt ctacccgctc gaagttttcc tcagtaccgt
     2521 gcagcgcaat cgcctccagc gctggtttta acgaatcggg caacgttgac cagtcagaaa
     2581 gtgccacgcc ccgcatatag ccaaagcacc actcctcaac aatcgtcagc tcgctgccat
     2641 caacttctcg caagccgaat aacggctcaa actgctccgg gaattcgttc agacgctctg
     2701 cggtatcggc catatgttga aaagccagat tcataaagcg cgtcatctct ttctctgacg
     2761 cccagcgcgg cacatagtca gccccacccc acacggcaac cagccactgt tccggttcaa
     2821 tctcttgcgg agaactcaac accgccgtca ataaaccgtc cagctccgcc acatcaagga
     2881 tggcgtggtc agtgttgtat ttggtcagaa tatcgtccag ccattccaac tcactttcgt
     2941 ttaacggtcc cgttttcata cgcttttcct tgtggatctc aactcgccag cacctatctt
     3001 acatgccggt ccgtatcaga gatacttttt gagtggcttt gctggtgatt aaaaattaag
     3061 gagggtgtaa cgacaagttg caggcacaaa aaaaccaccc gaaggtggtt tcacgacact
     3121 gcttattgct ttgattttat tcttatcttt cccatggtac ccggagcggg acttgaaccc
     3181 gcacagcgcg aacgccgagg gattttaaat cccttgtgtc taccgattcc accatccggg
     3241 ctcgggaaga aagtggaggc gcgttccgga gtcgaaccgg actagacgga tttgcaatcc
     3301 gctacataac cgctttgtta acgcgccaaa ttcttcaggc ctttcagcca gacatccgct
     3361 tgacgccgat gtcttttaaa ctggagcggg aaacgagact cgaactcgcg accccgacct
     3421 tggcaaggtc gtgctctacc aactgagcta ttcccgcatt catcaagcaa tcagttaatc
     3481 acttgatttt attatcgtct ggcaatcagt gccgccgttc gatgcgttgc attctactta
     3541 cctggcgcga tgagtcaacg atatttttca ccacttttga tcgtttgctg aaaattacgc
     3601 cgaaacgatc actgatcaag caaatctgca cgcgcagcgc tcaaatattg caacattgac
     3661 cacagagtca gtaccgcagc cacaaagaaa agtgcaatac cggcgtactc aacccaaatg
     3721 ttcggacgcc acagcagcca tgccaacgcc accatctggg cagtggtttt cactttccca
     3781 atccaggaga cggccacgct actgcgttta cccaactccg ccatccattc gcgtagcgca
     3841 gaaataataa tttcacgggc gatcatcgtt gccgccggta atgtcaccca ccagctgtga
     3901 taatgctcgg ttaccagcac catggcgata gccacgagaa ctttatctgc cacagggtca
     3961 aggaaagcac caaaccgggt actctggttc cagcggcgtg ccagaaaacc atcgaaccag
     4021 tcagtcaccg ccgcgacgca gaaaatgagc gcggcggcaa acggcgacca ggtgacaggc
     4081 agataaaaga ccaatacaaa gaatgggata aggatgacac ggaacagtgt aagcaacgta
     4141 gggatattaa attgcataat gacgggtaac tatctgttgt cagtaagatt acccctatgt
     4201 tgctacagag acatcaatgt ttcaacgacc agaagatctt ttctgccaga ccttgcgaaa
     4261 tacccggcac ttttgcaatt tcctcgacgc tggcgttacg taaaccttgc aaaccgccca
     4321 tatatttcaa caacatttgc cgacgttttg gcccgacgcc ttcaatggtt tccagggaac
     4381 tggtattttt gaccttcgcc cgttttttac ggtgcccgcc aatcgcgtga tcatgtgatt
     4441 catcgcgaat atgctggata acatgcagcg cgggtgaatc tggcggcaaa ctaaatccct
     4501 caccttccgg ctcaaagaac agcgtttcca gtccagcctt acgatctgct cctttggcaa
     4561 cgccaagtag cagcggatga tttttatccc atgagacatc cagttcggcg aagacatttt
     4621 tcgcctgcgc aagctggcct ttgccgccgt cgataaggat cacatccggg atcttactgt
     4681 cgtcaatggc tttaccataa cgccgacgca gcacctgatt catcgccgca taatcatcgc
     4741 ccggcgtgat gcctgtaatg ttatagcgcc gatactccgc acgcagcggg ccgttagcat
     4801 caaacaccac acaggaagcg acggtttgtt cgcccatggt atggctgatg tcaaagcact
     4861 ccatccgctt cacttccggc aatttcaaca cgctggcaag cgcggtcagt cgctggtgaa
     4921 cggtagattg ctgcgaaagt ttgctggtta aggccgtcgc cgcattggtg cgcgcgagtt
     4981 tcagataacg cgccctatcg ccgcgaggtt tggtttgaac attaatcttg cgtcccgcca
     5041 gttctgaaag ggaatcggcg agcagcgttt tatcgctaag attaaaatcg agcaggatct
     5101 cacccggtaa ggtgcgcatc tggctgcctt gtaaatagaa ctggcctacg aaggtttcta
     5161 ccacctcgct cagttccgta ccgccaggca ctttcgggaa atagctgcgg ctgccgagca
     5221 ctttgccctg acgaatgaac aatacgtgga cacaagccat gcccgcatcg aacgccacac
     5281 caataacgtc gaggtcgtcg ccggtattgg aaacgaattg tttttcggtg acgcgtcgca
     5341 ccgcctgaat ttggtcgcga atacgtgcag cttcttcaaa ctccagattc tggctggcag
     5401 tttccatacg actaatgagt tgcgtaagca cctgatcatc tttgccagac aaaaacaggc
     5461 gcacatactc gacctgctga gcgtattctt cttcactcac cagtccttca acgcacggtc
     5521 ccagacagcg ccctatctgg tattgcagac acggacgcga gcgattgcga taaacactat
     5581 tttcgcactg gcgaatgggg aaaatctttt gcagtagcgc cagtgtttca cgtacggcat
     5641 agccattcgg gaacgggccg aaatattcac ctttggcatg cttcgcacca cgatgcatcg
     5701 ccagacgcgg gtgggtatca ccactcagga agataaaagg atatgattta tcatcgcgta
     5761 gcaaaacgtt gtaacgcggc tgatagagtt tgatgtagtt gtgttccagc aacagcgctt
     5821 cggtttctgt gtgagtaacc gttacatcaa tttgctggat ctgggcgacc agcgcttcgg
     5881 ttttgcgcga agcgaggttg ctacggaaat agctggagag ccgttttttc aggtctttcg
     5941 ctttgccgac atagataacc gtaccaccag catcgtacat gcgataaacg cctggctggc
     6001 tggttacggt ttttaaaaac gcttttgcgt caaactgatc actcactgac ttgataatgt
     6061 ctccgcatta cacagaccat ggcgaattgc caggtgagtc agctcaacat cgccatgaat
     6121 gtttagttta ctgaacatac gatagcggta gctgttcacc gttttcggac tgagattgag
     6181 ctgttctgag atctcattga ccttctggcc cttggtgatc atcagcataa tctgcaattc
     6241 acgttcagac aaactggcaa atgggctttc tgttttttct ggttcgatct ggcttaacgc
     6301 catttgttga gcgatgtcag aagcaatgta acgctgccct gaatagacag aacgaatcgc
     6361 actcacgact tcctgcggag ccgcgccttt gctgaggtag cccgcagcac cggcctgcat
     6421 gactttcgct ggtaaagggt tttctgtatg gacggtaagc atgatgattt tgacatcagc
     6481 tgtggaacgc gcgattttac gcgtcgcctc aagaccgcca atgcccggca tactcatgtc
     6541 cattagcacc acgtcaacgg catttgtccg gcaccactta acggcgtctt caccgcacga
     6601 tgcctcaccg acgactttta taccctttat atcttccaga atgcgtcgta tccctgcgcg
     6661 caccagttcg tggtcatcaa caagtagaac gttgatcaaa ggaatatctc cagaaatagg
     6721 gataacgcta ctgatagtta gtcattcgta tattagcggt ttttattgca actttgaaac
     6781 gttaaaaatg gtgggtattc gatttttctc tcgtttttgt caattcgatt gtccacagtt
     6841 atggtcacgc ccgtcaccaa cggcttaccg gatcgtttca cagtaagccc tgcgacgaaa
     6901 tgtgacaaaa attaccttta ttcagcaaaa atgaaaatca gcccgctgaa tatgtaacat
     6961 taattaaccc gaacaatacg ggcaaaaaac attcatgata aaaatattta ttggtcatta
     7021 tattaacgca tttaatagca ccgttgacga tacgctcaaa aaacaaccac tgctattttt
     7081 agcaaagctt atggtatact ccgccgcctt aacatttttc accgcaaatt ttcattgcaa
     7141 catgacgagg aaaataaatg agtacgcctg atttttctac tgccgagaat aatcaagaac
     7201 tggcaaatga agtctcctgc ctgaaagcga tgctgacgct gatgctgcag gcgatgggac
     7261 aagctgacgc gggccgcgtg atgttaaaga tggaaaaaca gcttgcgctg atcgaagacg
     7321 aaacccaggc tgcagtattt tccaaaacgg ttaagcaaat taaacaagcc taccgtcagt
     7381 aatataaaac cggctgatag cgtgcctttc agccggtttt tgcatctggc acgcaggaca
     7441 gaaaagagat caaattaagc cagtagcggc cgcgtaacag gcaacctggg tcttattcgg
     7501 tgcattgatt tttttctgca tgtttttctg atggaaattg accgtattct cagagattga
     7561 caaaatcatc gctatctctg ctgatgtctt cccttccgcc gtccatttca aaatttcttt
     7621 ttcgcgcttg ctgaaattca tctctggcgt catcactatt tcatcattta aacgcatcag
     7681 agccatcaga ctttcgcgca ccagtaactg catttttaat tgcagttcat cactaagaat
     7741 gggtatttcg cgcgcgctgc tacgggaaaa ggacaaaaag cccagcgccc ggtttggcag
     7801 cattaaatac tgagtgacac cgcggcgtaa accatgtgcg cgcgcggctt cccataacgg
     7861 ctgtgcttcg ctgaataagt catcattcca cattaaatgg ccctgactaa agttttcagg
     7921 gttcagcacc ggatcaattg cgagaaagtt ttttgcctga taataactaa cccacgcctc
     7981 agggtaattg gtgtagaaag ccactttagg tcgcgtgaat ggtaccgggt ggcgaacaca
     8041 taacgaatag taatcgtact ctagctgctg agcctgaagc tctatttcat ggtagacctc
     8101 ttctgcggcc tccatcctct gaaaacgcaa cagcatcgtg cgacgccagc tgaaaaaatc
     8161 cgtatcctgc atagtaaacc gcaacgcccc tgagagtgag tatcatttat aatgataatt
     8221 caaactatca cataaataag atttatatat aatttatatt attcaggcaa tgaattactt
     8281 ttgcaagcca tcgcattctc ttatgttatt aatgagttat gctgatttgt taagctgttt
     8341 tatcacgctt gaaatggcgt cccgccccga caggtgaatc gtcggggctg attttttctt
     8401 attattgcag cagaaacttc tcgaggaact ggcgggtgcg aggctgctgg ggatcggcaa
     8461 ataacgcttt tgctgccccc tgctcgacta tccgcccctg gtccataaaa atcgcccggt
     8521 ccgcaacatc ccgggcaaag ctcatttcgt gcgtcacaat caccatcgtg cgcttttcct
     8581 gcgccagctg acggatggtg ttcaggactt cgcccaccag ctctggatcc agcgccgacg
     8641 ttggctcgtc aaacaaaatc acctcaggac gcattgccag cgcacgtgca atcgcaacac
     8701 gttgctgttg accgccagac aaacgacgtg gatagctggt ttctttaccg gccagcccaa
     8761 ctttcgccaa cagctcgcga gcgcgcgccg tggcctcttc tttcggttcg cctttgacga
     8821 tcaccggccc ttcaataatg ttttccagca ccgtacgatg cggaaacaaa ttaaagttct
     8881 ggaagacaaa cccgacgtgc tgacgcaact ggcgaatcag cgatttttgc tgacttaatg
     8941 aacgtgcagt atcaatagtg atatcgccaa cggtgatagt tcccgcttcc ggttgttcca
     9001 gcagatttat gctgcgtagc aacgtggttt tgccggaacc actcggaccg ataattgcca
     9061 ccacttcgcc aggctttacc tcaaggtcga taccgtgcag caccgtctga ccgtgaaatt
     9121 ttttcaccag gttcttaact tcaatggcac tcattttggt tctctctcct ggcgattaag
     9181 ttgattctca aaatggttct gcaacgtcga taatactgtc gccatgatcc agtagatgag
     9241 cgaagccgcc aggtacatgg tgaacacctc cagcgtgcgc gaggtaatca actgcgcctg
     9301 acggaacagc tccggcacct gaattgtcgc ggccagcgac gtatctttta ccaggctgat
     9361 aaagctgttc gacagcggcg gcaacgccac ccgcgccgcc tgtggcaaaa tcgcgcgacg
     9421 catagtctgc catggcgtca taccaatact ggcagctgct tcccactgac ctttatcaat
     9481 agaagaaatg gcggcgcgca gcgtttcggc agcataggcg gcagtgttga gcgacagacc
     9541 aatcattgct gacggaatgg gatctaattc gataccaaac tgcggcaggc cgtaatagat
     9601 cataaacagt tgtgcgatga gcggtgtacc acgaaaaata gagatataaa aacgcgccag
     9661 ccagcgcacg ggccagattg gcgacaggcg catcagcgcg agaataaacc cgagcagtaa
     9721 gccaaaaaac atgccgccga tactgagttg cagcgtatac ccagcccctt tcagcaggaa
     9781 cggcaaggaa tcaataacca gttgtatact ttcttgcatg agcgttcccg gagctaaacg
     9841 tggggatgat aggcgaacag cgcaggcgca ccgccggtat gaataaacag aatcggccct
     9901 tcatctttga aacgtttctg actgataccg tcaatcagac ccgccatcgc ttttccggta
     9961 tacacaggat caagcagaat gccttccagc cgcgccagca atttcactgc ttccatgcct
    10021 tcgtcgttcg gcacgccgta gccaggtgca aaatagtcat cccagagtaa aatttccgct
    10081 gatgcggtca gctccagttc tttcgcaatc gcctgttgta ggttaaccac tttcggcaat
    10141 tgatcggcaa cggaacgcga cacggtcacg ccaatcagtt cgctttcagg catcaggtgt
    10201 tccagcccaa cagccagtcc ggcgtgagtt ccggcactgc ccgatgcgac caccaccgac
    10261 gaaatattaa ccgccccttc acactgttgc gcgatttcca gcgcactctc cacataaccc
    10321 agcgcgccca gagcattaga accgccaacc ggaatgacat acgggcgaaa gccttgtgct
    10381 tcgactcgcg tcgccagctc ttccagttgg gcattgggat cggtcagtgc gtcgcacatt
    10441 tcaatctggg tattgaacag atccagcaac aagcgattgc cgttggttaa atagttttct
    10501 gcggttgtgc caataggatt ttccagcagc gccacgcagt gcagaccgag tttggcagcg
    10561 actgcggcag tctggcgcac atggttagac tggatcgccc cggcagtaat cagcgtatcg
    10621 gcaccttcgc gcagagcatc tgccgcgaga aattctagct tacgtaattt attgccgccc
    10681 attgccatgg gggtgacgtc atcccgtttg atgaaaattt cccgtcctag ataatcagaa
    10741 aagcgcggca gatattcgag cggcgttggc gcgccgataa actccaaccg tggaaaacgg
    10801 gttaaattat gcagtggcat aacagcctcc gatgtgtgtt gttgtgattt tcttattatg
    10861 cacgctgaaa acgcgtaaat aaaaaaggcg ctagtgaaag cgcccttttt tgtcattatg
    10921 ctgattattt ggtcacatca gcaccaaacc atttttcgga aagcgcttgc agagtgccgt
    10981 ctttttgcat ttccgcaatt gcatcattca ccgctttcag caggtcttca tttcctttac
    11041 gcagcgccac gccagactcc tgacgggaga atgcttcacc ggttactgcc agcgtatcgt
    11101 tggttttctt caccagatcc agcgccgcca gacggtcaac gaggatcgca tcgatacggc
    11161 ctacgcgcag atcctgatat ttggtcgggt catcatcata ggtacgcaca tcgacaccct
    11221 gaacattctg ccgcagccac tcttcatagt tggtgcccag accgacaccc acttttttgc
    11281 ctttcagatc agcagctgtt ttaatggtgc cttcgttacc ttttttcacc agcgcctgaa
    11341 tgccggaaat ggtgtaaggg gtagagaaat cgtatttttt cttgcgctcg tcagaaatgg
    11401 tgacctgatt aatcaccaca tcaatgcgtt tagaatccag cgacgccagc ataccgtccc
    11461 atttggtcgg ttttagggac gcctcaacgc caagatgttt tgccagctgt tgggcaaatt
    11521 ccacttcaaa accggttaat ttgccgtcat ccccctgaaa actgaacggc ggataagttc
    11581 cttccagacc taccagcagc gtgccgcgct ctttgacttt attaagcaga ccttcatctg
    11641 caaaactttt aacgctcatg cccgcaacca gcgccacggc catcacaccc atcaatgcct
    11701 gacgtcccag atgtgctaat ttcatattca ccccgaatgt tgttatgtct gtttgcagtg
    11761 tagagccatt gtttgtaaac acaaaaacaa ctccgcta
//
LOCUS       DAPHKZ010000140        11180 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.140, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000140 DAPHKZ010000000
VERSION     DAPHKZ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11180
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.140"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..267)
                     /locus_tag="RH288_003909"
     CDS             complement(<1..267)
                     /locus_tag="RH288_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032915.1"
                     /translation="MSQNDIIIRTHYKSPHRLHIDSDIPTPSSEPINQFARQLITLLD
                     TSDLSSMLSYCVTQEFTANCRKISQNCYSTALFTINFATSPIHTE"
     gene            791..2719
                     /gene="thrS"
                     /locus_tag="RH288_003910"
     CDS             791..2719
                     /gene="thrS"
                     /locus_tag="RH288_003910"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDV4032916.1"
                     /translation="MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEL
                     VDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
                     DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEV
                     IEKLQQEIRSRSLKQLEE"
     gene            2723..3265
                     /gene="infC"
                     /locus_tag="RH288_003911"
     CDS             2723..3265
                     /gene="infC"
                     /locus_tag="RH288_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDV4032917.1"
                     /translation="MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            3362..3559
                     /gene="rpmI"
                     /locus_tag="RH288_003912"
     CDS             3362..3559
                     /gene="rpmI"
                     /locus_tag="RH288_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDV4032918.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            3612..3968
                     /gene="rplT"
                     /locus_tag="RH288_003913"
     CDS             3612..3968
                     /gene="rplT"
                     /locus_tag="RH288_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDV4032919.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     misc_feature    4085..4209
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            4091..4135
                     /gene="pheM"
                     /locus_tag="RH288_003914"
     CDS             4091..4135
                     /gene="pheM"
                     /locus_tag="RH288_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheST operon leader peptide PheM"
                     /protein_id="HDV4032920.1"
                     /translation="MNAAIFRFFFYFST"
     gene            4419..5402
                     /gene="pheS"
                     /locus_tag="RH288_003915"
     CDS             4419..5402
                     /gene="pheS"
                     /locus_tag="RH288_003915"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDV4032921.1"
                     /translation="MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
     gene            5417..7804
                     /gene="pheT"
                     /locus_tag="RH288_003916"
     CDS             5417..7804
                     /gene="pheT"
                     /locus_tag="RH288_003916"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDV4032922.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHG
                     VVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPIGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNQLPLVQPEIVPVGATIDDTLPITVEAPEACPRYLG
                     RVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGI
                     VVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLE
                     CAFFSPLSITGRARRHGLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVI
                     DITNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPS
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGTHREADLSLKRVKTLLNDKGYQ
                     EVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNR
                     VRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESV
                     LDLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            7809..8108
                     /gene="ihfA"
                     /locus_tag="RH288_003917"
     CDS             7809..8108
                     /gene="ihfA"
                     /locus_tag="RH288_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HDV4032923.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE"
     gene            8209..9189
                     /gene="btuC"
                     /locus_tag="RH288_003918"
     CDS             8209..9189
                     /gene="btuC"
                     /locus_tag="RH288_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HDV4032924.1"
                     /translation="MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWF
                     TPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGE
                     ISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR"
     gene            9252..9803
                     /gene="btuE"
                     /locus_tag="RH288_003919"
     CDS             9252..9803
                     /gene="btuE"
                     /locus_tag="RH288_003919"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thioredoxin/glutathione peroxidase"
                     /protein_id="HDV4032925.1"
                     /translation="MQDSILTTVVKDIDGEVTTLEKFAGNVLLIVNVASKCGLTPQYE
                     QLENIQKAWVDRGFMVLVFPCNQFLEQEPGSDEEIKTYCTTTWGVTFPMFSKIEVNGE
                     GRHPLYQKLIAAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGKVIQ
                     RFSPDMTPEDPIVMESIKLALAK"
     gene            9803..10552
                     /gene="btuD"
                     /locus_tag="RH288_003920"
     CDS             9803..10552
                     /gene="btuD"
                     /locus_tag="RH288_003920"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HDV4032926.1"
                     /translation="MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLA
                     RMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKT
                     RTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
                     MNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRRE
                     EVLTPPNLAQAYGMNFRRLDIEGHRMLISTI"
     gene            10630..11094
                     /locus_tag="RH288_003921"
     CDS             10630..11094
                     /locus_tag="RH288_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HDV4032927.1"
                     /translation="MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQS
                     WHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKQQASIGTQIDKDELLPGDL
                     VFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI"
BASE COUNT         2821 a         2618 c         3023 g         2718 t
ORIGIN      
        1 ttctgtatgg atgggtgaag tggcaaagtt aatggtaaaa agggcagtgg aataacaatt
       61 ttgtgatatt tttcgacagt ttgcggtaaa ttcctgagta acacagtatg acagcatcga
      121 acttaagtca gaggtatcaa gtagggtgat gagctggcgc gcaaattgat taataggctc
      181 tgatgaaggt gttggtatgt cgctatcgat gtgcaatcta tgaggagact tataatgagt
      241 tctgataatg atatcgtttt gactcataat ctgttcgcct tatatatatc tggaggtttt
      301 gaggatgatg attaattatt atcgccagaa cgaaatgtgc acgaaaaatt gttataagaa
      361 ttgtgtcact tttatcattg tgatatgacc acttcgtcat taatctcatg agcgtttaaa
      421 atactaccgc caaatcacgc aacgaacttt gctggattca gtttatgctg ctgtaaatcc
      481 gctcgcagta aacctttcag acgcaccgtg atgttatcag ttgttcttta agcgttttgc
      541 tggtgtactc actacaaacg aattgcgaat cgaatcaatg tgaaacggaa aggtacaatc
      601 tccctttttt tagtgttaac atcgctcaac cgggtggaag gtgagaggtt aatgtctttc
      661 atttgtgtac ctgattgcga accaatttag catttgttgg ctagatggtt tcgcaatgaa
      721 ctgttaataa acaaattttt ctttgtatgt gatctttcgt gtgggtcacc actgcaaata
      781 aggatataaa atgcctgtta taactcttcc tgatggcagc caacgccatt acgatcacgc
      841 tgtaagcccc atggatgttg cgctggacat tggtccaggt ctggcgaaag cctgtatcgc
      901 agggcgcgtt aatggcgaac tggttgatgc ttgcgatctg attgaaaacg acgcacaact
      961 gtcgatcatt accgccaaag acgaagaagg tctggagatc attcgtcact cctgtgcgca
     1021 cctgttaggg cacgcgatta aacaactttg gccgcatacc aaaatggcaa tcggcccggt
     1081 tattgacaac ggtttttatt acgacgttga tcttgaccgc acgttaaccc aggaagatgt
     1141 cgaagcactc gagaagcgga tgcatgagct tgctgagaaa aactacgacg tcattaagaa
     1201 gaaagtcagc tggcacgaag cgcgtgaaac tttcgccaac cgtggggaga gctacaaagt
     1261 ctccattctt gacgaaaaca tcgcccatga tgacaagcca ggtctgtact tccatgaaga
     1321 atatgtcgat atgtgccgcg gtccgcacgt accgaacatg cgtttctgcc atcatttcaa
     1381 actaatgaaa acggcagggg cttactggcg tggcgacagc aacaacaaaa tgttgcaacg
     1441 tatttacggt acggcgtggg cagacaaaaa agcacttaac gcttacctgc agcgcctgga
     1501 agaagccgcg aaacgcgacc accgtaaaat cggtaaacag ctcgacctgt accatatgca
     1561 ggaagaagcg ccgggtatgg tattctggca caacgacggc tggaccatct tccgtgaact
     1621 ggaagtgttt gttcgttcta aactgaaaga gtaccagtat caggaagtta aaggtccgtt
     1681 catgatggac cgtgtcctgt gggaaaaaac cggtcactgg gacaactaca aagatgcaat
     1741 gttcaccaca tcttctgaga accgtgaata ctgcattaag ccgatgaact gcccgggtca
     1801 cgtacaaatt ttcaaccagg ggctgaagtc ttatcgcgat ctgccgctgc gtatggccga
     1861 gtttggtagc tgccaccgta acgagccgtc aggttcgctg catggcctga tgcgcgtgcg
     1921 tggatttacc caggatgacg cgcatatctt ctgtactgaa gaacaaattc gcgatgaagt
     1981 taacggatgt atccgtttag tctatgatat gtacagcact tttggcttcg agaagatcgt
     2041 cgtcaaactc tccactcgtc ctgaaaaacg tattggcagc gacgaaatgt gggatcgtgc
     2101 tgaggcggac ctggcggttg cgctggaaga aaacaacatc ccgtttgaat atcaactggg
     2161 tgaaggcgct ttctacggtc cgaaaattga atttaccctg tatgactgcc tcgatcgtgc
     2221 atggcagtgc ggtacagtac agctggactt ctctttgccg tctcgtctga gcgcttctta
     2281 tgtaggcgaa gacaatgaac gtaaagtacc ggtaatgatt caccgcgcaa ttctggggtc
     2341 gatggaacgt ttcatcggta tcctgaccga agagttcgct ggtttcttcc cgacctggct
     2401 tgcgccggtt caggttgtta tcatgaatat taccgattca cagtctgaat acgttaacga
     2461 attgacgcaa aaactatcaa atgcgggcat tcgtgttaaa gcagacttga gaaatgagaa
     2521 gattggcttt aaaatccgcg agcacacttt gcgtcgcgtc ccatatatgc tggtctgtgg
     2581 tgataaagag gtggaatcag gcaaagttgc cgttcgcacc cgccgtggta aagacctggg
     2641 aagcatggac gtaaatgaag tgatcgagaa gctgcaacaa gagattcgca gccgcagtct
     2701 taaacaattg gaggaataag gtattaaagg cggaaaacga gttcaaacgg cgcgccctaa
     2761 ccgtatcaat ggcgaaattc gcgcccagga agttcgctta acaggtctgg aaggcgagca
     2821 gcttggtatt gtgagtctga gagaagctct ggagaaagca gaagaagccg gagtagactt
     2881 agtcgagatc agccctaacg ccgagccgcc ggtttgtcgt ataatggatt acggcaaatt
     2941 cctctatgaa aagagcaagt cttctaagga acagaagaaa aagcaaaaag ttatccaggt
     3001 taaggaaatt aaattccgtc ctggtacaga tgaaggcgac tatcaggtaa aactccgcag
     3061 cctgattcgc tttctcgaag agggtgataa agccaaaatc acgctgcgtt tccgcggtcg
     3121 tgagatggcg caccagcaaa tcggtatgga agtgcttaat cgcgtgaaag acgatttgca
     3181 agaactggca gtggtcgaat ccttcccaac gaagatcgaa ggccgccaga tgatcatggt
     3241 gctcgctcct aagaagaaac agtaaggcct tcaagtagca ctgtctgtgg agccttcggg
     3301 cttcacaggc tttgttcgcc tttgtttcgt ttattaacaa tgcgaagtgg aagttattaa
     3361 aatgccaaaa attaagaccg tacgcggtgc tgctaagcgc ttcaaaaaaa ccggtaaagg
     3421 tggttttaag cacaagcacg ctaacctgcg tcacattctg accaaaaaag cgaccaaacg
     3481 taaacgtcac ctgcgtccga aagccatggt ttccaaaggc gatctgggcc tggtaatcgc
     3541 gtgcctgccg tacgcataag ccgttaacgt ttttaacttt ttaattagaa tatagataca
     3601 ggagagcaca tatggctcgc gtaaaacgtg gtgttattgc acgtgcacgt cacaagaaaa
     3661 ttttgaaaca agctaaaggc tactacggtg cgcgttctcg cgtataccgc gttgccttcc
     3721 aggctgttat caaagctggt cagtatgctt accgtgaccg tcgtcaacgt aagcgtcagt
     3781 tccgtcaact gtggattgcg cgtatcaacg cagcagcacg tcagaacggt atttcttaca
     3841 gcaaattcat caatggcctg aaaaaagcct ctgttgaaat cgaccgtaag atcctggctg
     3901 atatcgcagt attcgacaaa gtagcgttca ccgctctggt tgaaaaagcg aaagcagctc
     3961 tggcataagc cagttgaaag agggagctag tctccctctt ttcgtttcaa cgccatcaaa
     4021 acattgactt ttatcgccgt agccttttca ataaaggtct tttgaagagt accaaaaggt
     4081 aacgcaagca atgaatgctg ctattttccg cttctttttt tactttagca cctgaatcca
     4141 ggaggctagc gcgtgagaag agaaacggaa aacagcgcct gaaagcctcc cagtggaggc
     4201 tttttttgta tgcgcgtttt gaaaaataaa aagcctgtct catcaggtgt aattgtcgca
     4261 gccagactgg acacggccag cgcggagaaa ccggagcgta tttaagtacg tgagaatttc
     4321 gagcacagcc cgggaccaaa atggcaagta aaatagcctg atgggatagg ctctaagtcc
     4381 aacgaaccag tgtcaccact gacacaatga ggaaaaccat gtcacatctc gcagaactgg
     4441 ttgccagtgc gaaggcggcc attagccagg cgtcagatgt tgccgcgtta gataatgtgc
     4501 gcgtcgaata tttgggtaaa aaagggcact taacccttca gatgacgacc ctgcgtgagc
     4561 tgccgccaga agagcgtccg gcagctggtg cggttatcaa cgaagcgaaa gagcaggttc
     4621 agcaggcgct gaatgcgcgt aaagcggaac tggaaagcgc tgcactgaat gcgcgtctgg
     4681 cggcggaaac gattgatgtc tctctgccag gtcgtcgcat tgaaaacggc ggtctgcatc
     4741 cggttacccg taccatcgac cgtatcgaaa gtttcttcgg tgagcttggc tttaccgtgg
     4801 caaccgggcc ggaaatcgaa gacgattatc ataacttcga tgctctgaac attcctggtc
     4861 accacccggc gcgcgctgac cacgacactt tctggtttga cactacccgc ctgctgcgta
     4921 cccagacctc tggcgtacag atccgcacca tgaaagccca gcagccaccg attcgtatca
     4981 tcgcgcctgg ccgtgtttat cgtaacgact acgaccagac tcacacgccg atgttccatc
     5041 agatggaagg tctgattgtt gataccaaca tcagctttac caacctgaaa ggcacgctgc
     5101 acgacttcct gcgtaacttc tttgaggaag atttgcagat tcgcttccgt ccttcctact
     5161 tcccgtttac cgaaccttct gcagaagtgg acgtcatggg taaaaacggt aaatggctgg
     5221 aagtgctggg ctgcgggatg gtgcatccga acgtgttgcg taacgttggc atcgacccgg
     5281 aagtttactc tggtttcgcc ttcgggatgg ggatggagcg tctgactatg ttgcgttacg
     5341 gcgtcaccga cctgcgttca ttcttcgaaa acgatctgcg tttcctcaaa cagtttaaat
     5401 aaggcaggaa tagattatga aattcagtga actgtggtta cgcgaatggg tgaacccggc
     5461 gattgatagc gatgcgctgg caaatcaaat cactatggcg ggcctggaag ttgacggtgt
     5521 agaaccggtt gccggcagct tccacggcgt ggtcgttggt gaagtggttg agtgtgcgca
     5581 gcatccgaac gctgacaaac tgcgtgtgac aaaagtgaat gtcggcggcg atcgcctgct
     5641 ggacatcgtc tgcggtgcgc caaactgccg tcagggcctg cgtgtagcgg tagcgaccat
     5701 tggtgctgtt ctgccgggtg atttcaaaat taaagcggcg aaactgcgtg gcgaaccgtc
     5761 tgaagggatg ctgtgctcct tctctgaact gggcatttct gacgatcaca gcggcattat
     5821 cgaactgcct gcggatgcgc cgattggcac cgatatccgt gaatacctga aacttgatga
     5881 caacaccatc gaaatcagcg tgacgccaaa ccgtgccgac tgcttaggca tcattggtgt
     5941 tgcgcgtgac gttgccgtgc tgaaccagct gccgctggtt caaccggaaa tcgttccggt
     6001 tggtgcgacc atcgacgaca cgctgccgat tacagtcgaa gcgccggaag cctgcccgcg
     6061 ttatcttggc cgtgtggtaa aaggcattaa cgttaaagcg ccaactccgc tgtggatgaa
     6121 agaaaaactg cgtcgttgcg ggatccgttc tatcgatgca gttgttgacg tcaccaacta
     6181 tgtgctgctc gaactgggcc agccgatgca cgctttcgat aaagatcgca ttgaaggcgg
     6241 cattgtggtg cggatggcga aagagggcga aacgctggtg ctgctcgacg gtactgaagc
     6301 gaagctgaat gctgacactc tggtcatcgc cgaccacaac aaggcgctgg cgatgggcgg
     6361 catcttcggt ggcgaacact ctggcgtgaa tgacgaaaca caaaacgtgc tgctggaatg
     6421 cgcgttcttt agcccgctgt ctatcaccgg tcgtgctcgt cgtcatggcc tgcataccga
     6481 tgcgtctcac cgttatgagc gtggcgttga tccggcactg cagcacaaag cgatggaacg
     6541 tgcgacccgt ctgctgatcg acatctgcgg tggtgaggct ggcccggtaa ttgatatcac
     6601 caacgaagca acgctgccga agcgtgcaac catcactcta cgtcgtagca aactggatcg
     6661 cctgatcggc catcatattg cggatgagca ggtaactgac attctgcgtc gtctcggctg
     6721 cgaagtgacc gaaggcaaag acgaatggca ggcagttgcg ccgagctggc gtttcgatat
     6781 ggagattgaa gaagatctgg ttgaagaagt cgcgcgtgtt tacggctaca acaacatccc
     6841 ggatgagccg gtacaggcaa gcctgattat gggtactcac cgtgaagctg acctgtcgct
     6901 caagcgcgtg aaaacgctgc tcaacgacaa aggctatcag gaagtgatca cctacagctt
     6961 cgttgatccg aaagtgcagc agatgatcca tccaggcgtt gaagccttac tgctgccaag
     7021 cccgatctct gttgaaatgt cagcaatgcg tctttctctg tggactggcc tgctggcaac
     7081 cgtggtgtac aaccagaacc gtcagcagaa ccgtgtgcgc attttcgaaa gcggtctgcg
     7141 tttcgtacca gatactcagg caccgttggg cattcgtcag gatctgatgt tagccggtgt
     7201 gatttgcggt aaccgttacg aagagcactg gaacctggca aaagagaccg ttgatttcta
     7261 tgatttgaaa ggcgatcttg aatccgttct cgacctgacc ggtaaactga atgaggttga
     7321 gttccgtgca gaagcgaatc cggcactgca tccggggcaa tccgcagcga tttatctgaa
     7381 aggtgaacgt attggttttg ttggggttgt tcatcctgaa ctggaacgta aactggatct
     7441 taacggtcgc actctggtgt tcgaactgga gtggaacaag ctcgcagacc gcgtggtgcc
     7501 tcaggcgcgc gagatttctc gcttcccggc gaaccgtcgt gacatcgcgg tggtggtcgc
     7561 agaaaacgtt cccgcagcgg atattttatc cgaatgtaag aaagttggcg taaatcaggt
     7621 agttggcgta aacttatttg acgtgtaccg cggtaagggt gttgcggagg ggtataagag
     7681 cctcgccata agcctgatcc tgcaagatac cagccgtaca ctcgaagaag aggagattgc
     7741 cgctaccgtc gccaaatgtg tagaggcatt aaaagagcga ttccaggcat cattgaggga
     7801 ttgaacctat ggcgcttaca aaagctgaaa tgtcagaata tctgtttgat aagcttgggc
     7861 ttagcaagcg ggatgccaaa gaactggttg aactgttttt cgaagagatc cgtcgcgctc
     7921 tggaaaacgg cgaacaggtg aaactctctg gttttggtaa cttcgatctg cgtgataaga
     7981 atcaacgccc gggacgtaac ccgaaaacgg gcgaggatat tcccattaca gcacggcgcg
     8041 tggtgacctt cagacccggg cagaagttaa aaagccgggt cgaaaacgct tcgcccaaag
     8101 acgagtaatc tgatctaact aaaaaggccg ctctgcggcc ttttttcttt tcactgtcga
     8161 agagtcaccg taaaatcaac gccatgacac ttcagcagaa cggataccat gctgacactt
     8221 gcccgccaac aacagcgaca aaatattcgc tggttattat gcctgtcagt tttgatgctg
     8281 ctggcgcttc tcttaagcct ttgcgccggt gaacaatgga tctcgccagg tgactggttt
     8341 actcctcgtg gcgaactgtt cgtctggcaa attcgcctgc cacgtacgct ggctgtattg
     8401 ctggttggtg cggcgctggc tatatccggc gctgtaatgc aggcgttgtt tgaaaatcct
     8461 ctggcagaac ctggactact tggcgtctct aacggcgcag gcgtggggct tatcgccgcg
     8521 gtattgcttg ggcaagggca actccccaac tgggcgctag ggctgtgtgc gattgctggc
     8581 gcgcttatca tcactttaat actcttacgt ttcgcccgtc gtcatctttc gaccagtcgg
     8641 ttattgctgg ctggcgttgc attagggatt atctgtagcg cactaatgac gtgggctatc
     8701 tacttttcca cctcagttga tttgcgtcag ctgatgtact ggatgatggg cggttttggc
     8761 ggcgtagact ggcggcaaag ctggctgatg ctggcattga tccccgtgtt gttgtggatc
     8821 tgttgtcagt ccaggccgat gaatatgtta gcacttggcg agatctcggc gcggcaactg
     8881 ggtttacccc tgtggttctg gcgcaatgtg ctggtggcag cgaccggctg gatggttggc
     8941 gtcagtgtgg cgctggcggg tgctatcggc tttattggtc tggtgatccc ccatattctc
     9001 cggttgtgtg gtttaaccga tcatcgcgta ttacttcccg gctgcgcgct ggcaggggcg
     9061 agcgcattgc tgctggccga tattgtagcg cgcctggcat tagctgccgc agagctgcct
     9121 attggcgtgg tcaccgcaac gttaggtgcg ccggtgttta tctggttatt gttaaaagca
     9181 ggacgttagc cgcaaaaaga cggtctatga ttaaaagcta agatttttac tgaccacacc
     9241 caggagaaac gatgcaagat tccattctga cgaccgtagt gaaagatatc gacggtgaag
     9301 tgaccacgct ggagaagttc gccggtaatg tgctgttgat tgtcaatgtc gcctcaaagt
     9361 gtggcttaac gccgcaatat gagcagttgg agaatattca gaaagcctgg gtcgatcgag
     9421 gttttatggt gctggtattc ccgtgcaacc agtttctgga acaagaaccg ggcagcgatg
     9481 aagagattaa aacttactgt accaccacat ggggggtgac gttcccgatg ttcagtaaga
     9541 ttgaagttaa tggcgaagga cgccatccgc tgtatcaaaa attgattgcc gcagcgccga
     9601 ccgcagtcgc gccggaagag agcggattct atgcccgtat ggtcagcaaa ggccgtgcac
     9661 cgctgtaccc ggatgatatt ttatggaatt ttgaaaaatt cctggttggc agggacggaa
     9721 aagtcatcca gcgtttttcc ccggatatga cgccggaaga tcccattgtg atggaaagca
     9781 ttaaactggc gttggcaaaa taatgtctat tgtgatgcag ttacaagatg ttgcggaatc
     9841 tacccgcctg gggccgcttt ctggcgaggt tcgggctggg gagatcctgc acctggtggg
     9901 gccgaatggc gcgggtaaga gtaccttact ggcgcgaatg gccggaatga ccagcggtaa
     9961 gggaagcatt cagttcgcgg ggcaaccact ggaagcatgg tccgcaacaa aactcgcgct
    10021 gcatcgcgcc tatctttcac aacagcagac gccgccgttt gcaatgccgg tctggcacta
    10081 cctgacactg catcagcacg ataaaacgcg taccgaacta ctgaatgatg tcgcaggggc
    10141 gctggctctt gatgacaaac tcggacgtag caccaatcaa ctttccggcg gtgaatggca
    10201 acgcgtacgt cttgctgcgg tggtgttgca aatcacacca caagccaatc ccgcaggcca
    10261 attgctgctt cttgatgagc cgatgaacag tcttgatgtt gcgcaacaaa gtgcgttaga
    10321 caaaattctg agcgcgctgt gtcagcaagg actggcgatt gtgatgagca gtcacgatct
    10381 caaccacaca ttgcgtcatg cgcatcgggc gtggttgcta aaaggtggaa aaatgctggc
    10441 cagtggacgc agggaagagg tgctcacgcc gccaaatctg gcgcaggcct atgggatgaa
    10501 ttttcgccgt ctggatatcg aaggtcacag aatgctgatt tcgaccatct gatttcatta
    10561 gtatcttgaa aatcgggtaa ttacgacgct aaattaatgc aagaataaaa aacagaggaa
    10621 ccgtacggaa tgcgtttctg ccttattttg atcacagcac tgcttctggc cgggtgtagc
    10681 caccataaag caccgccgcc aaatgccaga ctttctgatt cgattaccgt tattgccggt
    10741 ttgaacgacc agctacaaag ctggcatggc acgccgtatc gttatggtgg catgacgcgg
    10801 cgcggtgtgg actgttcggg atttgtggtt gtgacgatgc gcgatcgttt cgatttgcag
    10861 ctgccccgtg aaaccaaaca acaagcctct attggcacgc aaattgataa agacgagttg
    10921 ctgccaggtg acctggtctt tttcaaaacg gggtccggac aaaatggttt gcatgtaggt
    10981 atttacgata ccaacaacca atttatccac gcctctacca gcaagggagt gatgcgttcc
    11041 tcacttgata atgtctattg gcagaaaaat ttctggcagg cgagacgaat ctagtatgtc
    11101 gaaaaatgga cggcgatgat acatcgccgt ccatttactc ctgaatacag tagtattttg
    11161 cagacaaaaa ttccgtaaat
//
LOCUS       DAPHKZ010000141        11026 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.141, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000141 DAPHKZ010000000
VERSION     DAPHKZ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11026
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.141"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            49..642
                     /locus_tag="RH288_003922"
     CDS             49..642
                     /locus_tag="RH288_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001755143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDV4032928.1"
                     /translation="MLIGYVRVSTNDQNTELQRNALECAGCERIFEDKISGTKSDRPG
                     LKKLLRTLSEGDTLVVWKLDRLGRSMRHLVILVEELRERGVNFRSLTDAIDTSTPMGR
                     FFFHVMGALAEMERELIVERTRAGLEAARAKGRIGGRRPKLTASEWEQAGRLLAAGES
                     RQRVALIFDIGLSTLYKKFPSSAAKNKLCHPLANRDK"
     gene            702..1892
                     /locus_tag="RH288_003923"
     CDS             702..1892
                     /locus_tag="RH288_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HDV4032929.1"
                     /translation="MSDYHHGVQVLEINDGTRVISTVSTAIVGMVCTASDADAETFPL
                     NKPVLITNVQSAIAKAGKKGTLAASLQAIADQSKPVTVVVRVEDGTGDDEETKLAQTV
                     SNIIGTTDENGQYTGLKALLAAESVTGVKPRILGVPGLDTKEVAVALASVCQKLRAFG
                     YISAWGCKTISEVKAYRQNFSQRELMVIWPDFLAWDTVSSTTATAYATAHALGLRAKI
                     DQEQGWHKTLSNVGVNGVTGISASVFWDLQESGTDADLLNESGVTTLIRRDGFRFWGN
                     RTCSDDPLFLFENYTRTAQVLADTMAEAHMWAVDKPITATLIRDIVDGINAKFRELKT
                     NGYIVDATCWFSEESNDAETLKAGKLYIDYDYTPVPPLENLTLRQRITDKYLANLVTS
                     VNSN"
     gene            1905..2423
                     /locus_tag="RH288_003924"
     CDS             1905..2423
                     /locus_tag="RH288_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HDV4032930.1"
                     /translation="MAMPRKLKLMNVFLNGYSYQGVAKSVTLPKLTRKLENYRGAGMN
                     GSAPVDLGLDDDALSMEWSLGGFPDSVIWELYAAIGVDAVPIRFAGSYQRDDTGETVA
                     VEVVMRGRQKEIDTGEGKQGEDTESKISVVCTYFRLTMDGKELVEIDTINMIEKVNGV
                     DRLEQHRRNIGL"
     gene            2480..2755
                     /locus_tag="RH288_003925"
     CDS             2480..2755
                     /locus_tag="RH288_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001719230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HDV4032931.1"
                     /translation="MNKENVITLDNPVKRGEQVIEQVTLMKPSAGTLRGVSLAAVANS
                     EVDALIKVLPRMTAPMLTEQEVAALELPDLVALAGKVVGFLSPNSVQ"
     gene            2788..2907
                     /locus_tag="RH288_003926"
     CDS             2788..2907
                     /locus_tag="RH288_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001496926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HDV4032932.1"
                     /translation="MADVAVIFHWPPSELYPMSLTELITWREKALRRSGNTNE"
     gene            2900..5347
                     /locus_tag="RH288_003927"
     CDS             2900..5347
                     /locus_tag="RH288_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV4032933.1"
                     /translation="MSNNVKLQVLLRAVDQASRPFKSIRTASKSLSGDIRETQKSLRE
                     LNGQASRIEGFRKTSAQLAVTGHALEKARQEAEALATQFKNTERPTRAQAKVLESAKR
                     AAEDLQAKYNRLTDSVKRQQRELAVVGINTRNLAHDEQGLKNRISETTAQLNRQRDAL
                     ARVSAQQAKLNAVKQRYQTGKELAGNMASVGAAGVGIAAAGTMAGVKLLMPGYEFAQK
                     NSELQAVLGVAKDSAEMAALRKQARQLGDNTAASADDAAGAQIIIAKAGGDVDAIQAA
                     TPVTLNMALANRRTMEENAALLMGMKSAFQLSNDKVAHIGDVLSMTMNKTAADFDGMS
                     DALTYAAPVAKNAGVSIEETAAMVGALHDAKITGSMAGTGSRAVLSRLQAPTGKAWDA
                     LKELGVKTSDSKGNTRPIFTILKEMQASFEKNRLGTAQQAEYMKTIFGEEASSAAAVL
                     MTAASTGKLDKLAAAFKASDGKTAELVNIMQDNLGGDFKEFQSAYEAVGTDLFDQQEG
                     ALRKLTQTATKYVLKLDGWIQKNKSLASTIGLIVGGALALIGIIGAIGLVAWPVITGI
                     NAIIAAAGAMGAIFTTVGSAVMTAIGAISWPVVAVVAAIVAGALLIRKYWEPVSAFFG
                     GVVEGLKAAFAPVGELFTPLKPVFDWLGEKLQAAWQWFKNLIAPVKATQDTLNRCRDT
                     GVMFGQALADALMLPLNAFNKLRGGIDWVLEKLGVINKESGTLDQTAARTQAATYGSG
                     GYIPATSTYAGYQAYQPVTAPAGRSYVDQSKNEYHISLTGGTAPGTPLDRQLQDALEK
                     YERDKRARARASMMHDG"
     gene            5362..5841
                     /locus_tag="RH288_003928"
     CDS             5362..5841
                     /locus_tag="RH288_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000978924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4032934.1"
                     /translation="MMLALGMFVFMRQTLPHQTMQRESDYRWPSNSRIGKRDAYQFLG
                     VGEENITLAGVLYPELTGGKLTMTTLRMMAEEGRAWPLLDGTGMIYGMYVISRVSETG
                     SIFFADGTPRKIDFTLSLTRVDESLAALYGDIGKQAESLIGKAGSMATRFTGMTGAG"
     gene            5841..7004
                     /locus_tag="RH288_003929"
     CDS             5841..7004
                     /locus_tag="RH288_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HDV4032935.1"
                     /translation="MLDALTFDAGSTLTPDYMLMLDSRDITGNISDRLMSMTLTDNRG
                     FEADQLDIELNDADGQVGLPVRGAVLTVYIGWKGFALVCKGKFTVDEVEHRGAPDVVT
                     IRARSADFRGTLNSRREGSWHDTTLGAIVEAIASRNRLEASVAPSLAGIKIPHIDQSQ
                     ESDVKFLTRLAERNGGEVSVKMGKLLFLKAGQGATASGKKIPQVTITRSDGDRHHFAI
                     ADRGAYTGVTAKWLHTKDPKPQKQKVKLKRKKKEKHLRALEHPKAKPVTQKKAPKVPE
                     AREGEYMAGEADNVFALTTVYATKAQAMRAAQAKWDKLQRGVAEFSISLATGRADIYT
                     ETPVRVSGFKRVIDEQDWTITKVTHFLNNSGFTTSLELEVRLSDVEYETEDDE"
     gene            7086..7304
                     /gene="ogrK"
                     /locus_tag="RH288_003930"
     CDS             7086..7304
                     /gene="ogrK"
                     /locus_tag="RH288_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage transcriptional regulator OgrK"
                     /protein_id="HDV4032936.1"
                     /translation="MFHCPLCQHAAHARTSRYITDTTKERYHQCQNVNCSATFITYES
                     VQRYIVKPGEVHAVRPHPLPSGQQIMWM"
     gene            complement(7623..9905)
                     /gene="pflB"
                     /locus_tag="RH288_003931"
     CDS             complement(7623..9905)
                     /gene="pflB"
                     /locus_tag="RH288_003931"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDV4032937.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT
                     EAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI
                     RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQSM"
     gene            complement(9960..10817)
                     /gene="focA"
                     /locus_tag="RH288_003932"
     CDS             complement(9960..10817)
                     /gene="focA"
                     /locus_tag="RH288_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HDV4032938.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGTMPFGMAKLVGGICFSLGLILCVVCGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRENDHH"
BASE COUNT         2750 a         2769 c         3079 g         2428 t
ORIGIN      
        1 ataacgggca actggcatca tctccggttt ttattcaggg ggatgctcat gcttattggc
       61 tatgtccgcg tatcaacaaa tgaccagaac acggaattgc agcgtaacgc gctggaatgc
      121 gcgggatgtg agcggatttt tgaggacaaa atcagcggca cgaagtccga caggccggga
      181 ctgaaaaaac tgctcaggac attatcggag ggggatacac tggtagtctg gaagctggac
      241 cggctggggc gtagtatgcg gcatctggtc attctggttg aggagctgcg cgaacgcggc
      301 gttaattttc gcagcctgac ggatgctatt gataccagca cgccgatggg gcgttttttc
      361 tttcatgtga tgggtgccct ggccgaaatg gaacgagaac tcattgtcga gcggacacgc
      421 gccggactgg aagcggccag agccaaaggt cgtattggtg gcagacgtcc gaaactcacc
      481 gcgagtgagt gggagcaggc cgggcggttg ttggctgcag gggaatcacg tcaacgcgtg
      541 gcgctgattt ttgatattgg cctgtccacg ctctataaaa aattcccctc atcagcggca
      601 aagaataaat tgtgtcatcc cttagccaac cgggacaaat agcctgacat ctccggcaca
      661 actgaaaata acactcaccc attaaccacg gagttaaacg gatgagtgac tatcatcacg
      721 gcgtgcaggt gctggagatt aacgacggca cccgcgtcat ttccaccgta tccactgcca
      781 ttgttggcat ggtctgcacg gccagcgatg cggatgcgga aaccttcccc ctcaataaac
      841 ctgtgctgat taccaatgtg cagagtgcaa ttgcaaaggc cggtaaaaaa ggcacgctgg
      901 cggcgtcgtt gcaggccatc gccgaccagt caaaaccggt caccgttgtc gtgcgtgtgg
      961 aagacggcac cggcgacgac gaggaaacga aactagcgca gaccgtttcc aatatcatcg
     1021 gcaccaccga cgaaaacggt cagtataccg gactgaaagc cctgctggcg gcggagtcgg
     1081 taaccggtgt taaaccgcgt attctcggtg tgccgggact ggataccaaa gaggtggctg
     1141 ttgcactggc atccgtctgt cagaagctgc gtgctttcgg atatatcagc gcatggggct
     1201 gtaagaccat ttccgaggtg aaagcctacc gccagaattt cagccagcgt gagctgatgg
     1261 tcatctggcc ggatttcctc gcatgggata cggtcagcag taccaccgcc accgcgtatg
     1321 ccaccgccca tgcgctgggt ctgcgcgcta aaatcgacca ggagcagggc tggcataaaa
     1381 cgctgtccaa tgtcggggta aacggtgtta ccggcatcag cgcctctgta ttctgggatt
     1441 tgcaggagtc cggcaccgat gctgacctgt tgaacgagtc aggtgtcaca acgctgattc
     1501 gccgtgacgg tttccgcttc tggggtaacc gtacctgctc tgatgacccg ctgttcctct
     1561 ttgaaaacta cacccgcacc gcgcaggtgc tggccgacac gatggctgag gcgcacatgt
     1621 gggcggtgga caagcccatc actgcaacgc tgattcgcga catcgttgac ggcatcaatg
     1681 ccaaattccg tgagctgaaa acaaacggct atatcgtgga tgcgacctgc tggttcagcg
     1741 aagaatccaa cgatgcggaa accctcaagg ccggaaaatt gtatatcgac tacgactata
     1801 caccggtgcc tcctctcgaa aacctgaccc tgcgccagcg tattaccgat aaatacctgg
     1861 caaatctggt cacctcggtt aacagcaatt aaggagcctg accgatggca atgccgcgca
     1921 aactcaagtt aatgaacgtc tttctgaacg gctacagcta tcagggcgtt gcaaagtccg
     1981 tcacgctgcc aaaactgacc cgtaagctcg aaaactatcg cggtgcgggg atgaacggca
     2041 gcgcaccggt agacctcggc cttgatgacg atgcgctgtc aatggagtgg tcgctcgggg
     2101 gcttcccgga ttcggttatc tgggagcttt acgccgcaat cggtgtggat gctgtgccga
     2161 ttcgttttgc aggctcttac cagcgcgacg ataccggcga aactgtggcc gtcgaggtgg
     2221 tcatgcgtgg acgtcagaaa gaaatcgaca ccggcgaggg gaaacaggga gaagacaccg
     2281 agtcgaaaat ctccgtggtc tgcacctatt tccggctgac gatggacggt aaggaactgg
     2341 tcgaaatcga caccatcaac atgattgaga aggtgaacgg cgtcgaccgg ctggaacaac
     2401 accgccgcaa tatcggcctg taattttcat ccggtcagcc tggctgaccg gttaaccccg
     2461 attcagaagt gagaaaacca tgaacaaaga aaatgtgatt accctggaca atccggtcaa
     2521 gcgtggtgag caggttatcg aacaggtcac gctgatgaaa cccagtgcgg ggacgctgcg
     2581 cggtgtcagt ctggctgcgg tcgcaaactc agaagtcgat gcactgatta aggtgctgcc
     2641 gcgcatgacg gcaccgatgc tgaccgagca ggaagtcgcc gcgttggaac tgcctgacct
     2701 tgtggcgctg gccggtaagg tggtcggttt tttgtcgccg aactcggtgc agtgacgttc
     2761 ccgaaaaatc tgtcggtcga tgacctgatg gcggatgtgg cagtgatatt tcactggccg
     2821 ccatcagaac tgtatcccat gagcctgacc gaactcatca catggcgcga aaaggcgctc
     2881 cggcgaagcg gaaacacgaa tgagtaacaa tgtaaaatta caggtattgc tcagggctgt
     2941 tgaccaggca tcccgcccgt ttaaatccat ccgcacagcg agcaaatcgc tgtcggggga
     3001 tatccgggaa acacaaaaat cactgcgcga gctgaacggt caggcatccc gtattgaggg
     3061 atttcgcaag accagtgcac agctcgccgt gactggtcat gcacttgaaa aggcacggca
     3121 ggaggccgaa gcccttgcca cacagtttaa aaacaccgaa cgtccgacac gtgctcaggc
     3181 gaaagtgctg gaatccgcaa agcgtgcggc ggaggactta caggcgaaat ataaccgcct
     3241 gacggattcc gttaaacgcc agcagcggga actggccgtt gtgggaatta atacccgcaa
     3301 tcttgcacat gatgagcagg gactgaaaaa ccgtatcagt gaaaccaccg cacaacttaa
     3361 ccgtcagcgt gacgcgctgg cgcgtgtcag tgcgcaacag gcaaaactta acgcagtaaa
     3421 acagcgttat cagacaggca aggaactggc cggaaatatg gcctcagtgg gcgctgccgg
     3481 tgtggggatt gcggcggcgg gaacgatggc cggagttaag ttgctgatgc caggttatga
     3541 gtttgcgcag aaaaactcag aattacaggc tgtgctcggt gtggcaaaag actccgccga
     3601 aatggctgca ctacgcaagc aggcgcgtca gctcggcgac aataccgcag cctcggcaga
     3661 tgatgcagcc ggtgcgcaga ttattattgc gaaagccggt ggggatgttg atgccattca
     3721 ggcggcaacg ccggtcacgc tgaatatggc gctggcgaac cgtcgcacga tggaagaaaa
     3781 cgccgccctg ctgatgggga tgaaatccgc ctttcagctt tcaaacgata aggtcgctca
     3841 tatcggggat gttctctcca tgacgatgaa caaaaccgcc gccgattttg acggcatgag
     3901 cgatgcgctg acctatgccg cacctgtggc aaaaaatgcc ggtgtcagca ttgaagaaac
     3961 cgccgcaatg gtcggggcgc tgcatgatgc aaaaatcaca ggctcaatgg cggggacggg
     4021 aagccgtgcc gtgttaagcc gcctgcaggc accgacggga aaagcatggg atgcactcaa
     4081 agagcttgga gtgaaaacct cagacagcaa gggaaacacc cggccaatat ttaccattct
     4141 gaaagaaatg caggccagtt ttgagaaaaa ccggctcggt actgcccagc aggctgaata
     4201 catgaaaact attttcgggg aggaggccag ctcagccgcc gccgtgctga tgactgccgc
     4261 ctcaaccgga aagctggaca aactggccgc tgcgtttaaa gcctcagacg gaaagaccgc
     4321 agaactggta aatatcatgc aggacaacct cggcggtgac tttaaggagt ttcagtccgc
     4381 ttatgaggcg gtggggactg acctgtttga ccagcaggaa ggcgcactgc gtaagctcac
     4441 tcagacggcc acaaagtatg tgttaaaact cgacggctgg atccagaaaa acaaatcact
     4501 ggcgtcaacc atcggcctta ttgtcggtgg cgcactggcg cttattggca tcatcggtgc
     4561 aattggtctt gtagcctggc cggttatcac cggcattaat gccatcatcg cggcagcagg
     4621 cgcaatgggg gcaatcttca cgacggttgg cagtgctgtt atgacggcca tcggggcgat
     4681 tagctggccg gttgtggctg tggtggccgc cattgtcgcc ggggcgttgc ttatccgtaa
     4741 atactgggag cctgtcagcg cattctttgg cggtgtggtt gaagggctga aagcagcatt
     4801 tgcgccagtg ggggaactgt tcacgccact taagccggtg tttgactggc tgggtgaaaa
     4861 gttacaggcc gcgtggcagt ggtttaaaaa cctgattgcc ccggtcaaag ccacccagga
     4921 caccctgaac cgttgccgtg acacgggcgt catgttcggg caggcactgg ctgacgcgct
     4981 gatgctgccg cttaatgcgt tcaacaaact gcgcggtggt attgactggg tactggaaaa
     5041 actcggcgtc atcaacaaag agtcaggcac acttgaccag accgccgcca gaactcaagc
     5101 cgccacgtat ggcagcggtg gttatattcc ggcgaccagc acttatgcag gttatcaggc
     5161 ttatcagccg gtcacggcac cggctggccg ctcttatgtg gaccagagta aaaacgaata
     5221 tcacatcagc ctgacgggcg gtactgcgcc ggggacaccg cttgaccgcc agttacagga
     5281 tgcgctcgaa aaatacgagc gggataaacg tgcgcgcgcc cgtgccagca tgatgcatga
     5341 cggttaagga ggtgacgaaa aatgatgctc gcgttaggta tgtttgtttt tatgcgccag
     5401 acgctgccac accagaccat gcagcgtgaa tcagattatc gctggccgtc aaattcccgt
     5461 atagggaaac gggatgccta ccagtttctc ggtgtgggtg aggaaaacat cacgcttgcc
     5521 ggtgtgcttt atcccgaact gaccggcggc aagctgacga tgaccacgct caggatgatg
     5581 gcagaggaag gccgggcgtg gccgttgctg gatggcaccg gcatgattta cggcatgtat
     5641 gtcatcagca gggtgagtga aacagggagt attttctttg cagacggcac accccggaaa
     5701 attgatttta cgctgtcgct cacccgcgtt gatgaatcac tggccgcgct ttatggcgat
     5761 atcggtaaac aggcggaatc gctcatcggt aaggctggca gtatggcgac cagattcacg
     5821 ggtatgacgg gggcgggata atgctggatg cgctgacatt tgatgcaggc agtacgctga
     5881 cgccggatta tatgctgatg ctcgacagca gggatattac cggcaatatc agcgaccgtc
     5941 tgatgagcat gaccctgacg gataaccggg gctttgaggc tgaccagctt gatattgaac
     6001 tgaacgatgc cgacgggcag gtcgggctgc cggttcgtgg cgctgtcctg acggtgtata
     6061 tcggctggaa aggttttgcc ctggtatgta aagggaaatt caccgttgat gaggttgaac
     6121 accggggcgc accggatgtg gtcaccatcc gcgcccggag tgcagatttt cgcgggacgc
     6181 tcaattcccg ccgtgaaggc tcctggcatg acaccacgct cggtgcgatt gttgaggcga
     6241 tagcctcccg taacaggctg gaagccagtg tcgctccgtc actggccgga attaaaatcc
     6301 cgcacatcga ccagtcgcag gagtccgatg tgaaattcct gacccgtctt gctgaacgca
     6361 acggcggtga ggtgtcggta aaaatgggaa aactgttgtt tctcaaagcg gggcaggggg
     6421 cgacggccag cggtaaaaaa atcccgcagg tcaccatcac ccgcagcgac ggcgaccgtc
     6481 atcattttgc gattgctgat cgtggagcct acaccggcgt aacggcaaag tggttacaca
     6541 ccaaagaccc gaagccgcaa aagcagaagg taaaactgaa acgcaaaaag aaagagaaac
     6601 acctgcgcgc actggagcac ccgaaagcga aaccagtcac gcagaagaaa gcgccaaaag
     6661 taccggaagc gcgcgaaggt gaatacatgg ccggtgaggc tgacaacgtt tttgccctga
     6721 ccacggtata tgccacgaaa gcgcaggcca tgcgcgccgc tcaggcgaag tgggacaaac
     6781 tgcaacgggg cgttgcggag ttctccatca gccttgccac tggtcgggct gatatttaca
     6841 cggaaacgcc ggtcagagtg tcaggcttta agcgcgtcat agacgagcag gactggacaa
     6901 tcactaaggt gacacatttt ctgaataata gcggcttcac gacgtcctta gagcttgagg
     6961 tcaggctttc tgatgtggag tacgaaacag aagatgatga gtgatgtttt tattttatct
     7021 gtttgtttta taaggataaa ttaactaaaa tggcaccatc aacaaaaccg gaagaggtgc
     7081 tcgcgatgtt tcattgtcct ttatgccagc atgccgcaca tgcgcgtaca agtcgctata
     7141 tcactgatac gacaaaagag cgttatcacc agtgccagaa cgtgaattgc agcgccacgt
     7201 tcatcactta tgagtcggta cagcgataca tcgtgaagcc gggagaagtc cacgccgtaa
     7261 ggccgcaccc gttgccgtca gggcagcaaa ttatgtggat gtaattacaa acaggaagcc
     7321 cctcagtcga ggggcttttt tgtcgatgtg gtcaatgtgt ggacgtgacc agaaataaat
     7381 ccttttattt catgtaatta gatatcaaaa aatgtcacca ataactgaca ttgcggtgtt
     7441 tctccagatg tggcccatct gaggccgtgt tggtgcgcag ctcgaaggct acgtcgagtc
     7501 tgttttggca gtcaccttaa agtatagata gctgacaaaa aaggctctcg cgctaaaaaa
     7561 ggccccactt tcgtggagcc tttattgtac gctttttact gtacgatttc agtcaaatct
     7621 aattacatag attgagtgaa ggtacgagta ataacgtcct gctgctgttc tttagtcagc
     7681 gagttgaaac gtactgcgta gccagataca cggatggtca gttgcggata tttttccggg
     7741 ttttccatcg cgtcgagcag catttcacgg ttcatcacgt taacgttcag gtgctgacca
     7801 ccttcgatgg atgcttcgtg gtggaagtaa ccatccatca gaccagccag gttggtctta
     7861 cgaacttcgt cgtctttacc cagtgcgttc ggaacgatag agaaggtgta ggagatacca
     7921 tctttagcgt aagcaaacgg cagtttagca acggaagtca gagaggctac tgcacctttc
     7981 tggtcacgac cgtgcatcgg gttagcaccc ggtccgaacg gcgcgccagc acgacgaccg
     8041 tctggggtgt tacccgtttt cttaccatac acaacgttag aagtgatggt cagaacagac
     8101 tgagtcggga tagcgtcacg gtaggtgtgc agtttctgaa ttttcttcat gaaacgttct
     8161 accaggtcaa cagccaggtc atctacacgc ggatcattgt taccaaactg cgggtattcg
     8221 ccttcgattt cgaagtcgat agccagaccg tcttcgtcac gaatcggttt aactttcgca
     8281 tatttgattg cagacaggga gtcagcagca acggacagac cagcgatacc acacgccatg
     8341 gtgcggataa cgtcacggtc gtgcagcgcc atcagagagg cttcgtagct gtacttgtcg
     8401 tgcatgtagt ggatgatgtt cagtgcagtg atgtactgtt tagccagcca gtccatgaag
     8461 tgatccatgc gctccatcac ttcatcatag ttcaggacat cgcctttgat cggttcagac
     8521 ttcggaccaa cctgcatttt cagtttttcg tcaacgccgc cgttgattgc gtacagcatg
     8581 gttttcgcca ggtttgcacg cgcaccgaag aactgcattt gtttaccaac gatcatcggg
     8641 cttacgcagc aagcaatagc gtagtcatcg ttgttgaagt ccggacgcat caggtcatcg
     8701 ttctcatact gcagagaaga ggtgtcgatg gacactttag cggcgaattt cttgaagttc
     8761 agcggcagtt tttcagacca cagaatggtc atgttcggtt ccggagacgg acccatggtg
     8821 tacagggtgt tcaggaaacg gaagctgttt ttggtaacca gggtacgacc gtcgaggccc
     8881 ataccaccga tagattcggt tgcccagatc gggtcgccag agaacagttc atcgtattcc
     8941 ggagtacgca ggaagcgaac catacgcagt ttcatgacca ggtggtcaac catttcctgc
     9001 gcttcttgtt cggtgatctt gccagctttc aggtcacgtt cgatgtacac atccaggaag
     9061 gtggaggtac gaccgaagga cattgcagca ccgttctgag acttaacagc agccaggtag
     9121 ccgaagtaag tccactggat agcttcctga gcgttggtag ccggaccaga gatgtcgtag
     9181 ccgtatttcg cagccatttc tttcatctga cccagagcgc ggtgctgttc agcgatttct
     9241 tcgcgcagac ggatagtctg ttccaggttt acgccgtttt ccagatcagc ctgcagagaa
     9301 gtgaactgtg ccagtttgtc tttcatcagg tagtcgatac cgtacagcgc aacgcgacgg
     9361 tagtcaccga tgatacggcc acggccatat gcatctggca gaccggtcag aacaccagat
     9421 ttacggcaac gcaggatgtc cggagtgtaa acgtcgaaca cgccctggtt gtgagtttta
     9481 cggtattcag tgaagatttt tttgatcatc ggatccagtt cgcggttgta cgctttgcag
     9541 gaaccttcga tcattttgat accaccgaac gggataagag cacgtttcag cggagcttca
     9601 gtctgcagac caacgatttt ctcaagctgc ttgttgatgt agccagcgtc gtgagaggtg
     9661 atggtggaag caacagcggt gtcaaagtca actggcgcgt gagtgcggtt ttccagttta
     9721 acgccttcca ttactttgtc ccacagggtg gtggtcgctt cagtagcgcc agccaggaag
     9781 gactcgtcac cctcgtacgg agtgtagttt ttctgaatga agtcacggac gtttacttca
     9841 ttctgccagt cacctttggt aaaaccttcc caggctgtgg ctaacttttc attaagctcg
     9901 gacatgtaac acctaccttc ttaagtggat tttttattta ctgcgtactt cgacaaccat
     9961 taatggtggt cgttttcacg caggtaaatg acccagtatg tcaacccaac caacaaacca
    10021 ccaccgataa tgttgccgat cgtaaccgga atcaggttat cagtgatgaa attcatcacg
    10081 gtcaggtgag aaaaattttc cggtgcagaa ccgactgcgg tccaaaattc cggggatgcg
    10141 aagtcgcgga ttacaatacc catcgggatc ataaacatgt ttgcgatact gtgctcaaaa
    10201 ccgctggcaa caaacatcgc gaccggcagc accataatga acgctttgtc catcaggctg
    10261 cggccagaat aactcatcca tactgccaga cataccatca ggtttgccag gataccaaga
    10321 cagacggcct caataaaagt atggtgcact ttgtggtcgg cggtttgtag gacgtttagt
    10381 ccccattgac catttgcggt catatactcg ccggaaagcc acattaaaag tacaaacagc
    10441 agtgcgccga ccaggttgcc aaaatagaca tttagccagt ttttcgccaa ctgaccccag
    10501 gtgatgcgcc cactcgcctt agcaacaaca atcaacacgg tggaagtaaa gagatcggct
    10561 ccgcagacaa cacaaagaat cagccccaga gagaagcaaa tgccgccaac cagttttgcc
    10621 atgccgaagg gcattgtgcc tgtgccagtg gttgctgtga tatagaagac gaatgcgatt
    10681 gagatgaaaa caccggcggt aatcgccaga tagaaagtct taagcggatg tttcgttgct
    10741 ttatagacac ccgcctcttc ggccactttg gccattgcag caggaagtaa aagatcaaaa
    10801 gggttgtcag ctttcacact aactctctct ttattaagtc ggcgacgaga tactaacaaa
    10861 gcattataga tgagaaattg atatagatca tatctcgcct ggcttatagg cccgtaactc
    10921 gcatggtttt tatgcaaata cggagtaaat atttgattat ccaaataaaa ataaatttta
    10981 aaaattaaca aatgagttga attttttccg catcctccgc taaaac
//
LOCUS       DAPHKZ010000142        10978 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.142, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000142 DAPHKZ010000000
VERSION     DAPHKZ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10978
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.142"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            471..1538
                     /gene="pilL"
                     /locus_tag="RH288_003933"
     CDS             471..1538
                     /gene="pilL"
                     /locus_tag="RH288_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001360287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis lipoprotein PilL"
                     /protein_id="HDV4032939.1"
                     /translation="MKKNYLTLILPSLLSGCAGISGSNNVAPSDTPALVFVDGQISES
                     AGVLALTQQRLSPPKITPPPRVSVPETVKTAHPVSESRPLPSPTISQNFSRLIITGKP
                     GSAPVTLSPTARNRTVSQWIKTLLPEGWKFRQENAATPKLNTKLVSWSANDQWTRSLN
                     RLLEEQHLWGHLDWDNKTLTVTTSAAAPAQDTATTISPAAMVTTSTSPESPTTANSQN
                     KPRNPFRGNSVSSSTPAATPTPTGSTVKSIPLMTGTPVKPVSQGKEWRAPAGTTLREN
                     IIKWAEETKCESMASTHWMVIWPLSVTDYRLDAPLMFRGSFESAMEQVFELYRTAQKP
                     LYAQASRMQCIITVSDTRDGR"
     gene            1538..1975
                     /gene="pilM"
                     /locus_tag="RH288_003934"
     CDS             1538..1975
                     /gene="pilM"
                     /locus_tag="RH288_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilM"
                     /protein_id="HDV4032940.1"
                     /translation="MGWLVMAVGLTILIITGSYQNQKMSETTNAQQYASASVWASQIL
                     MIANRINDIRYVSGQQDGVISSDKLALPVTPDSRIKHQLQQGRLWVWMPEQPGLVETL
                     RSKSRGSALIGIFQNGQLTWLSGTATGLTPPAGITAGSVVYVN"
     gene            1989..3671
                     /locus_tag="RH288_003935"
     CDS             1989..3671
                     /locus_tag="RH288_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN family type IVB pilus formation outer
                     membrane protein"
                     /protein_id="HDV4032941.1"
                     /translation="MKKSHQRSMKLAVLPCMIAVALSISGCTFSEINKMQKKAQEDSA
                     HAREKVSALSARKSQALTWLDNQWINPVPVAQVSREKKQTAPACYITQARKGEITLQE
                     LGQRITAVCGIPVIITPDAANSTLEGGATRQMTGTLPAPDENGRLPLSSLGSTTMTTS
                     TQPLTLNNLMWQGDINGLLDLMASRSGLYWRMDNGRIVFYLTETRTYPLHMLNTKTSS
                     SSSVSSGSTSTMGATGGQDNSASGDATSSQSTTVGQEYDLYEDIRKTIEAMLTPEKGR
                     YWLSASSSTLTVTDTPAVQEAVARYVDEQNSIMNRQVALNVQVLSVSNTRNEQFGLDW
                     NLVYKSLHSAGATLNNASGDFTGATSAGVSILDTATGNAAKFSGSSLLIKALSEQGDV
                     SVVTSQESTVTNLTPVPIQMADQTVYVAQSATTTTTDVGATTTLTPGMITTGFNMTLL
                     PLIQKTGNLQLQMNFNLSDPPTIRSFTSKDGNSYIEMPYTKLRSLSQKVNLKEGQSLV
                     VTGFDQNNTTTSKAGTFTPANPLFGGSQTGKNERSTLVIIITPTFPSGGNNG"
     gene            3664..4959
                     /gene="pilO2"
                     /locus_tag="RH288_003936"
     CDS             3664..4959
                     /gene="pilO2"
                     /locus_tag="RH288_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001682966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4b pilus protein PilO2"
                     /protein_id="HDV4032942.1"
                     /translation="MADEDINPVVLLADPKVNHRVWAACLKWSPVVKKQRVPSHQKHK
                     PHVKSRRLTSLKVTVGSRSSRGKISRITGTGILARPERNHYFSLALAFCSWVRNGYGV
                     FRYSDKELLFLASINGQPAVMADLSGNDADVAQKVSLFLTMNEEPPEKWQVVSPLEHP
                     DNWESIITRLSSADLRRCKLTVGNRSKFTLPAVLFLVAASAGTVFWMTQPEPDVVPTP
                     EEIAARARLQFKKPDPPPELPHPWASQPVISDFLKACADLRKPSPVALEGWKLTGGTC
                     TPETFTLIYERQPGGTIEGFLARSKEIFNVIPDFNLKDGARLASVTRPLPSLPRRDEA
                     VPTPSEQLMRVFTWFQKKQLTPAINEIAIPEPLPGNDGEPAPVQKWKEYQFSLSTPVN
                     PDELFPLFQDTGVRLSNIHFELNGGTFSYSSEGHIYASR"
     gene            4946..5398
                     /gene="pilP"
                     /locus_tag="RH288_003937"
     CDS             4946..5398
                     /gene="pilP"
                     /locus_tag="RH288_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilP"
                     /protein_id="HDV4032943.1"
                     /translation="MRPGKLLIIPSIFFFSGFSFATTQPLVTIGELEAQQNRNILLQA
                     KVQGAQLQKQLEESDVTSSSETVSGFSGVTASLPSVSEQPTSKNRKELPVIMEINGKD
                     KRLNAVLRMADGRQTSVTTGSQLPGTSVTVKSISLSGVTLSDGTTLTF"
     gene            5409..6962
                     /gene="tadA"
                     /locus_tag="RH288_003938"
     CDS             5409..6962
                     /gene="tadA"
                     /locus_tag="RH288_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDV4032944.1"
                     /translation="MDKYNLKDALLFISRGDTHEILIETNQRTRPDVQSNLQELLKLY
                     PDINPKVVSLSELQEAGQDEKNRGPKERIIHLKDLADVSESEKKVLSYFETARKLGAS
                     DIHFLISESIFKVRMRIFGELQTVDEDQPALGYSLCATAILSMADVTETSFFPQREQD
                     ARLSPQLMRKIGIFGARYSHRPTGDGLIAVMRLIPDDGDKVPTFKQLGFIPEQIRLLN
                     IMLRRPEGKIVLSGPTGSGKSTTLRSACRVYLDDNQGRHLLTIEDPLEGQILGATQTP
                     IICDKSDEDAVKLAWSRAISSAMRLDPDAIMEGEMRDLISMMSTTYAAQTGHIVLTTL
                     HTNSALGIPERMITMGMNADLICDAQLLIGMISQRLVPTLCPSCRIPWEKRAPELSDD
                     ERDYLERHCNKDSLCSTDNIWFRNHHGCSECNHDVIINGRKRGEIGKGLTGRTVIAEV
                     IEPDNRLFQILKTRGKVAARKYWLENMKGISRVEHLLRRINEGLVDPLEADRIIPLDE
                     DERLSIDDV"
     gene            6975..8072
                     /locus_tag="RH288_003939"
     CDS             6975..8072
                     /locus_tag="RH288_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001699973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDV4032945.1"
                     /translation="MREMNFSQRLRRFIVRKTFSAPYRVQFYEALRFLLENKQPLKTA
                     LEQMRDAWTDFGRKWHPFAELATDCIESLRENSGENSLEYTLSLWVPQEEAAVISAGI
                     RSGSIVDALQFATTLTDAKEQIHQAIWQMAIYPVGLLIMMTGTLYVLNTELIPELSKI
                     SSPDSWSGALGFLYGLSVFVDNYGAICAVLFAVITGLISWSLPNWKSPDSVRTFADKI
                     MPWSIYQDIQGATFLLNMAALLKAKMTTLNSLNILQEFASPWLSTRLDSIIYRVRQGD
                     HLGLALRQCGYQFPSREAANFLSLLQGDGATELISNYGQRWLSQTLQRVKKRANVIRL
                     IMLIFLVMSLMLLVFAIMDIQSISDNSMGNF"
     gene            8090..8704
                     /locus_tag="RH288_003940"
     CDS             8090..8704
                     /locus_tag="RH288_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilX"
                     /protein_id="HDV4032946.1"
                     /translation="MLVENINTTLTGNNKKNEPHDKGWAILEQGTIALVVLFVIVVVL
                     GSLYALRTRANVATETANIQTIITSAQSLLKGSDGYTFTSSAKMTGALIQMGVIPSGM
                     TVQGDKTSGTATLYNAWGGAVTVAPASTSGFNNGFTVTYDKVPQDACIQIATRISKTG
                     LTNGITLNSTAHSDGKVTTEEASTQCKADNGSTGTNKLIFTING"
     gene            8714..9274
                     /locus_tag="RH288_003941"
     CDS             8714..9274
                     /locus_tag="RH288_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDV4032947.1"
                     /translation="MSGGTVPLRLISLILLFSLIPPARASYVAPKQIWTNKWDNCFAA
                     AGARYQIEPLLLKAISAGESSLRPGAININKDKKTGKASSTDYGLMQINSTHIPKLIN
                     MGVIKKSEDLITKPCLNIHIGSWILARHFQICGVSWNCLGSYNAGFRKDRHETREQYA
                     NKIWRIYRDMKGICLPGQGGRQCRQS"
     gene            9259..9915
                     /locus_tag="RH288_003942"
     CDS             9259..9915
                     /locus_tag="RH288_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDV4032948.1"
                     /translation="MQTIVGISLSPVYILPLMFTFSIIGRTLLFRVRYFLSDTGHLWY
                     KTHPAVLSGIWLYSIAVALIILSSSPLLYRIHAVLILSFILQMAVTDALTGLLPGTFT
                     RRFLIAGMLSQITTDIWWFRTTEFATAAIVLFCLHKLVNRHRLNIGTGDLWLIAGITA
                     WSGLYNAIWCVLLGTGGFVLWHSTWCIKGHKEGPLGPWLCFGHVLLLLDNLYQPLWVI
                     "
     gene            9915..>10978
                     /gene="pilV"
                     /locus_tag="RH288_003943"
     CDS             9915..>10978
                     /gene="pilV"
                     /locus_tag="RH288_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012565250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="HDV4032949.1"
                     /translation="MKKYDRGWASLETGAALLIVMLLIAWGAGIWQDYIQTKGWQTEA
                     RLVSNWTSAARSYIGKNYTTLQGSSTTTTPAVITTTMLKNTGFLSSGFTETNSEGQRL
                     QAYVVRNAQNPELLQAMVVSSGGTPYPVKALIQMAKDITAGLGGYIQDGKTATGALRS
                     WSVALSNYGAKSGNGHIAVLLSTDELSGAAEDTDRLYRFQVNGRPDLNKMHTAIDMGS
                     NNLNNVGAVNAQTGNFSGNVNGVNGTFSGQVKGNSGNFDVNVTAGGDIRSNNGWLITR
                     NSKGWLNETHGGGFYMSDGSWVRSVNNKGIYTGGQVKGGTVRADGRLYTGEYLQLERT
                     AVAGASCSPNGLVGRDNTGA"
BASE COUNT         3151 a         2602 c         2509 g         2716 t
ORIGIN      
        1 tttccccact acttttcaga tgcgtgcttc ttatcgtaag gtctgtatct aaatacaact
       61 tcacattctt tgcgaaaaaa aatggcagta aagaatcaag catacatctt agcccctatg
      121 ccgatacacg ttgcccggag tcaatgagga aacactggga tgtgttactt tctctgatat
      181 caaaagcaat taataatgat gaaaccattg ttatgcattc acatctcttt actcctgcaa
      241 gaataaataa acttataaag agactggaat cttatggttt gaatttctct gttattacat
      301 gcccacggaa aacaagtctg tatgaaagat tatcaattcc ttttgtatat ctcttatttc
      361 agtggtctct cccgcatttg cattcggacg gaatgacagt cgtcattcgt cctctccagc
      421 cgcctcacac caattaacaa acacgtatat acgaacacgg agtctccgtt atgaaaaaaa
      481 actatctgac acttatactg ccgtcattat tgtccggctg tgccggaatt tccggcagca
      541 ataacgtggc accatcagat acgcctgctc tggtttttgt tgacggacaa atcagtgaga
      601 gtgctggcgt tctggcactt acgcaacaac gtctttctcc acctaaaata actccccccc
      661 cgagagtcag cgtgccagag acagtaaaaa cagcacatcc agtcagcgaa tcccgaccgt
      721 taccttcacc aacaataagt cagaatttct cccggttaat cattacaggc aagcctggta
      781 gcgcccctgt aacactatcg ccgacggccc gtaaccggac cgtcagtcag tggataaaaa
      841 cattactacc ggaaggatgg aaattcagac aagagaatgc agccacgccc aagctgaata
      901 ccaaactggt ttcatggtct gccaatgatc agtggacccg ttctctgaat cggttgctgg
      961 aagaacaaca cctatggggc catctggact gggataataa aacgttgacc gtcacaacat
     1021 cagctgctgc accggcacag gacacggcaa ccactatctc gccagcagcc atggtaacca
     1081 catccacttc ccctgaatct ccaacaacag caaatagcca gaacaaacca cgaaatccat
     1141 tcagaggaaa cagcgtatct tcgtcaaccc ccgccgccac cccgactcca accggctcca
     1201 cagtcaagtc tatcccgctc atgaccggaa cgcctgttaa accggtatct cagggtaaag
     1261 agtggcgtgc gccggcaggc accacattaa gagagaacat tatcaagtgg gcagaagaaa
     1321 caaaatgcga aagcatggca tcaacgcact ggatggtcat atggccactt tctgtaaccg
     1381 attaccgtct ggatgcgcct ttaatgttcc ggggatcatt tgaatcagcc atggagcagg
     1441 tatttgagtt atatcggact gcgcaaaaac ctttatacgc acaggcttct cgcatgcagt
     1501 gcatcattac agtttctgat acaagggatg gtcgctaatg ggatggctgg tcatggccgt
     1561 cggcctgacc attctgatta tcactggtag ctaccagaat cagaagatgt ctgaaaccac
     1621 aaacgcccag caatatgcaa gtgcgtctgt atgggcaagt cagatactga tgattgctaa
     1681 cagaatcaat gatatcagat acgtatcagg ccagcaggac ggagtaattt cctcagataa
     1741 actggctctc cctgtcactc cggactcccg aattaaacat cagttacaac aggggcgtct
     1801 gtgggtatgg atgcctgaac aaccaggtct tgttgaaact ttgcgttcaa aaagtcgtgg
     1861 ttctgcacta atagggatct tccaaaacgg gcaactcacc tggctatcag gaactgcaac
     1921 cggtctgaca cccccggcag gcattactgc tggttctgtc gtctacgtta actaatctgg
     1981 atatattcat gaaaaaatca caccagcgtt caatgaagct ggcggtgctc ccctgcatga
     2041 tcgccgtcgc tctttccatc tccggatgta ctttcagcga aatcaacaaa atgcagaaaa
     2101 aagcacagga agactcagca catgcacggg aaaaggtatc agccctttcg gcccgtaaat
     2161 cgcaggctct tacctggctc gataatcaat ggataaaccc tgttccggtc gctcaggtat
     2221 caagagagaa aaaacaaaca gctccggcct gctacatcac gcaggcaaga aaaggagaga
     2281 tcactctgca ggaactgggg caacgtatta ctgccgtatg cggcatccct gtgatcatca
     2341 cgcctgacgc agccaattca actcttgaag gaggcgctac ccgccagatg acaggaacac
     2401 taccagcacc agatgaaaat gggcgtctac cgttaagcag cctgggcagc acaacaatga
     2461 ctacctccac tcagccatta acgctgaata acctcatgtg gcagggagat atcaatggtc
     2521 ttctggatct gatggccagc cggagtggtc tgtactggcg catggataat ggtcggattg
     2581 tattctatct gactgaaacc agaacgtatc cacttcatat gctgaacacc aaaaccagca
     2641 gcagttccag tgtcagctct ggctcaacaa gcacaatggg ggcaacagga ggccaggata
     2701 actcagcatc cggtgatgca acgtcctctc agagcacaac cgttggtcag gaatacgatc
     2761 tgtatgaaga catccggaaa actattgaag caatgctgac accagaaaaa ggccgttact
     2821 ggttatctgc atcgagctca acgctgactg tcactgatac tccagctgtc caggaagccg
     2881 tcgcacgata tgtggacgaa caaaacagta ttatgaaccg ccaggtagcc ctgaacgtac
     2941 aggttctgag cgtcagcaat accagaaacg aacagttcgg tctggactgg aaccttgttt
     3001 ataaatcgct acattccgcc ggagcaacgt tgaacaatgc aagcggagat tttacaggcg
     3061 ctacatctgc aggcgtatca attctggata cggcaacagg gaatgccgcc aaattcagcg
     3121 gttccagtct tctgattaaa gcgctgagtg aacagggcga tgtcagtgtt gtgacttcac
     3181 aagaaagcac tgtcacaaac ctgacgccgg tacctatcca gatggcagat cagacggttt
     3241 acgtcgccca gtcagcaaca acaacgacta cggatgtagg agcaacaaca acattaacgc
     3301 cgggcatgat caccaccgga ttcaatatga ccctgctgcc tttaattcag aaaacgggca
     3361 atctccagtt gcagatgaat tttaatctgt cagatccccc aacaatccgt agctttacgt
     3421 caaaagacgg aaacagttac atcgaaatgc cgtataccaa actgcgttca ctgagccaga
     3481 aggtcaatct gaaagaaggg caatcacttg tcgttactgg tttcgatcag aacaatacga
     3541 cgacaagtaa agccggtacg tttacgccag caaatccatt atttggtggt tcacaaaccg
     3601 ggaaaaatga acgcagcacg cttgtaatca tcattacccc gactttcccg tcaggaggca
     3661 acaatggctg atgaagatat caacccggtt gtacttctcg cagatcctaa agtaaatcat
     3721 cgcgtgtggg cagcctgtct taaatggagt cctgtcgtaa aaaaacagcg agtcccttct
     3781 catcagaaac acaagcccca tgtaaaatcc agacggctta cctctctgaa agtgactgta
     3841 ggcagcagaa gttcccgtgg gaagatcagc cgcattaccg gcacaggaat actggccagg
     3901 ccggagcgca atcattattt ttcccttgct ctggctttct gctcatgggt gagaaatgga
     3961 tacggcgtct tccggtacag cgataaggag cttttattcc ttgcctccat taatggccag
     4021 cctgccgtta tggctgatct gtcaggaaat gatgctgatg ttgctcaaaa ggtcagtctt
     4081 tttctgacga tgaacgaaga gccccccgaa aaatggcagg tcgtatctcc tctggaacat
     4141 cctgataact gggaaagtat tattacccgg ttatcatcag cagatctccg ccgttgcaaa
     4201 cttactgtcg gcaatcgcag caaattcaca ctgcctgccg tacttttttt agtagcagcc
     4261 agcgcaggca ctgtattctg gatgactcag ccagagccgg atgtcgtacc gacgcccgag
     4321 gagatagctg cacgggcaag attgcagttt aaaaagcccg atccaccgcc agaactcccg
     4381 catccatggg catcacaacc tgtaatcagt gattttctga aagcctgcgc ggaccttcga
     4441 aaaccatcac cggtcgcgct agaaggctgg aaacttaccg gtggaacatg tactcccgag
     4501 acattcacac tgatttacga acgacagcca ggaggaacta ttgaaggctt tctggcaaga
     4561 agcaaagaaa tctttaatgt tattcctgac tttaacctta aagatggtgc acgcctggct
     4621 tctgtaaccc ggccactgcc ttccctgccc cgcagggatg aggcagtccc taccccctca
     4681 gaacaactga tgcgggtgtt cacgtggttt cagaaaaaac agttaacgcc ggccattaat
     4741 gaaatagcca taccggaacc attaccaggt aacgatggtg aaccagcccc tgttcagaaa
     4801 tggaaagaat atcagttcag tttatcaacg cctgtaaatc ctgatgagtt gttcccttta
     4861 tttcaggata ccggcgttcg tctgagcaat atccattttg aattaaacgg cggtactttc
     4921 agttattcct cagaaggtca tatttatgcg tccaggtaaa ttactcatta ttccatccat
     4981 atttttcttc tccggttttt catttgcaac aacacaacct cttgtcacaa taggagaact
     5041 tgaagcacaa caaaaccgga atattctttt acaggcaaaa gttcagggcg cacagctaca
     5101 gaaacaactc gaagaatcag atgttacttc atcatctgaa actgtttcag gtttctctgg
     5161 tgtgactgcc tctttgccat cagtttcaga gcagccgaca tctaaaaaca gaaaggaatt
     5221 gcccgttatt atggaaataa acggcaaaga taaacgtctt aatgccgttc ttcgcatggc
     5281 tgatggacgt cagacaagcg tcaccactgg cagccagctt ccaggcacat ccgtcacagt
     5341 gaagtcgatc tcattgtctg gcgtcacgtt aagtgatggc accaccctta ctttctgagt
     5401 aacgtgatat ggataaatat aatctgaagg atgctctcct ttttatatcc aggggagaca
     5461 cccatgaaat tcttatagaa acaaaccagc ggacaaggcc tgacgtacaa agtaatctcc
     5521 aggagctgct aaaattatat ccggatatca acccaaaagt agtctcgttg tcggagttac
     5581 aggaggcagg tcaggatgag aaaaacagag gcccgaaaga acgaattatt catctgaaag
     5641 accttgctga tgtcagtgaa agtgagaaga aagttctatc ttattttgaa actgccagaa
     5701 aacttggtgc ttcagatatt catttcttaa tttcagagtc tattttcaaa gttcgcatga
     5761 gaatattcgg tgaactgcag actgtagatg aagatcaacc agcactgggc tattcacttt
     5821 gcgcaacagc cattctgtca atggctgatg tcactgaaac cagtttcttc cctcaaaggg
     5881 agcaggatgc gcgcctgtcc ccacaattaa tgcgaaaaat aggaatattt ggtgcacgct
     5941 acagtcacag acctacggga gacggtctga ttgcagttat gcgcctgata cccgatgacg
     6001 gagataaagt tcccacgttt aaacaactgg gctttatccc ggaacaaatc cggttgctga
     6061 acataatgct gcgccgcccg gaaggaaaaa tagtcctgtc aggtccaacc ggttccggta
     6121 aatcgacaac gttacgcagc gcctgccgtg tatatcttga cgataatcag gggcgacacc
     6181 tgctaacaat cgaagatccg ctggaaggac agatactggg agcaacacag actccgatta
     6241 tctgcgacaa atccgacgaa gatgccgtca aactggcatg gagtcgggct atttcatcgg
     6301 caatgcgact tgaccctgat gccatcatgg aaggggaaat gcgcgatctt atctcgatga
     6361 tgtcaaccac ctacgcggca cagaccgggc acatagttct gacgacatta catacaaact
     6421 cagctctggg tataccggag cgaatgatta cgatgggtat gaatgccgat cttatttgcg
     6481 atgcgcaatt actgattggg atgatcagcc agcgccttgt accaactctg tgtccctcct
     6541 gccgtattcc atgggaaaag cgagcacctg aacttagcga cgacgagcgt gattaccttg
     6601 agcggcactg caataaagat tcactctgca gtacagataa tatctggttc cgaaatcatc
     6661 acggatgctc tgaatgtaat cacgacgtaa tcattaacgg cagaaagcgc ggtgaaatag
     6721 gtaaaggcct caccggcagg actgtaattg ctgaggtgat agaacctgat aaccgcttat
     6781 ttcagattct gaaaacacgc ggcaaagttg cagcacgtaa atactggctg gaaaacatga
     6841 aaggcatcag tcgtgtagag catcttcttc gccgtatcaa tgaaggtctg gtagaccctc
     6901 ttgaagccga cagaatcatc cctctggacg aagacgagcg cctcagcatc gatgatgtct
     6961 aacaggagaa caacatgcgt gaaatgaatt tcagtcaacg gctgaggcgt ttcattgtca
     7021 gaaaaacgtt cagcgccccc tacagggtgc agttttacga agccctgcgt tttctgctgg
     7081 aaaataaaca gccattaaag accgcactgg aacagatgcg ggatgcctgg acagactttg
     7141 gacgaaaatg gcatcccttt gctgaactgg ccacagactg cattgagtct cttcgtgaaa
     7201 acagtggcga aaactctctg gaatatactc ttagtttatg ggttcctcag gaagaggccg
     7261 cagtaatcag cgccgggata agaagtggtt caattgtgga tgcactgcaa ttcgccacca
     7321 ctcttacaga tgcaaaagaa caaatccatc aggctatatg gcaaatggct atttatccgg
     7381 tgggattgtt aatcatgatg acggggacat tatatgttct gaatacagag ctaatacctg
     7441 aactgagcaa aataagctcc cccgattcat ggagtggtgc tcttggtttt ctttatggat
     7501 tatctgtttt tgtcgataat tacggcgcta tatgtgccgt tctttttgca gtgatcacag
     7561 gtttaatatc atggtctctg ccaaactgga aaagccctga cagtgttcgt acttttgccg
     7621 acaagataat gccatggagt atttatcagg atatacaggg agcaacattt ctcctgaata
     7681 tggctgcact tctgaaagcc aaaatgacga cgctcaactc gctaaacatt cttcaggagt
     7741 ttgcatcacc atggttaagc acacgtcttg acagcattat ttaccgcgtc cgccaggggg
     7801 atcatcttgg actggctttg cgtcagtgcg gttatcagtt cccatccagg gaagcagcca
     7861 acttcctgtc tttattacag ggagatggcg caacagagct aatcagcaat tatggtcaac
     7921 gatggcttag tcaaacactt caacgtgtaa agaaacgggc aaacgtgatt cgtttaatta
     7981 tgctgatatt tcttgtcatg tctctcatgt tactggtttt tgccattatg gatattcagt
     8041 ctattagtga caacagcatg ggtaactttt aaacaaaacg aggatattta tgttagtaga
     8101 aaatattaat accactttaa ctggaaataa taagaagaat gagcctcatg ataaaggatg
     8161 ggcaattttg gagcagggaa caatagcgct cgttgttctt tttgttatag tcgttgttct
     8221 gggtagtttg tatgcgttgc gtacaagagc caatgtggca actgaaaccg caaatataca
     8281 aacaattatc acaagtgccc agagcctgct aaaaggtagc gatggatata catttaccag
     8341 cagtgccaaa atgacaggtg ccctcattca gatgggtgtc attccctctg ggatgaccgt
     8401 acagggcgac aaaacatctg gtacagcaac gctctataac gcatggggcg gtgctgtaac
     8461 tgttgccccg gcttcaacat cagggttcaa caacggtttt accgttacct atgataaagt
     8521 cccacaggat gcctgtatcc agattgccac acgaatcagt aaaactggtt taactaacgg
     8581 cattaccctg aacagtactg ctcacagtga tggaaaagtc actactgaag aagccagtac
     8641 gcaatgcaag gcagataatg gcagcactgg tacaaacaaa cttatcttca ccatcaatgg
     8701 ttaaggagtt ttaatgtcag ggggtacagt acccctcaga cttatttcat taatcctgct
     8761 tttttctctt attccacccg cccgagcttc atacgtagct cccaaacaga tctggaccaa
     8821 caagtgggac aattgctttg ccgctgccgg cgcgcgctat caaattgaac cattattatt
     8881 gaaggctatt tctgccgggg aatcttcgtt gaggccgggc gcaattaata taaataagga
     8941 caaaaaaaca ggtaaagcca gtagcacgga ttatgggttg atgcaaataa actcaaccca
     9001 tattccaaag ctgataaata tgggcgtaat aaaaaagtct gaggatttaa ttaccaaacc
     9061 atgccttaat atccatatag gaagctggat actggcaaga cattttcaga tatgtggcgt
     9121 cagctggaat tgccttgggt catacaatgc cggattccgt aaggacagac atgaaacaag
     9181 agagcaatat gccaataaaa tatggagaat ttatcgtgac atgaaaggga tatgtcttcc
     9241 cggacaggga ggcaggcaat gcagacaatc gtaggcataa gtctatcccc tgtttatata
     9301 ctgccattga tgttcacatt ttccattatt ggacgaactc tgctattcag agttcgttat
     9361 tttttatctg atacgggaca tctctggtat aagacacacc ctgctgttct gtcaggaata
     9421 tggctataca gtatagctgt ggcgttaatt attttatcat catcaccact gctctaccgt
     9481 attcatgctg tccttattct ttcgttcata ctgcaaatgg cggtaacgga tgcactgaca
     9541 ggtttattac caggaacatt cacccgacgt tttttaattg caggaatgct atcacaaatc
     9601 acgactgata tatggtggtt ccgtacaaca gaatttgcca ctgctgcaat tgtcttattc
     9661 tgccttcata aattagttaa ccgccatcgt cttaatattg gcactggaga cctgtggctt
     9721 attgcaggta ttaccgcatg gtcagggtta tataacgcca tatggtgtgt gttgctgggc
     9781 acaggaggat ttgtcttatg gcattcaaca tggtgcataa aagggcataa agaaggccct
     9841 ctgggtccat ggctatgttt tggccatgtc cttttgctgc tggataatct ttatcaacca
     9901 ctatgggtaa tctgatgaaa aaatatgacc gaggctgggc atcgctggaa actggcgcgg
     9961 ctttactgat tgttatgctc ctgattgcct ggggagcggg catatggcag gactatattc
    10021 aaacaaaagg atggcaaact gaagcacgtc ttgtcagcaa ctggaccagt gcggcccgct
    10081 cttatatagg gaaaaactac acgactctcc agggcagtag taccacaaca actcctgccg
    10141 ttatcacgac aaccatgctg aaaaataccg gctttttgtc cagcgggttt actgagacaa
    10201 acagcgaggg gcagcggtta caggcatatg tggttcgaaa cgcccaaaac ccggaattac
    10261 tacaggcaat ggttgtatcc agtggtggca caccttatcc agtgaaagca cttatccaga
    10321 tggctaagga tattaccgct ggtcttggtg gatatatcca ggacggcaaa acagccacag
    10381 gtgcattacg ttcctggtca gtagctttaa gtaattatgg tgccaaaagc ggtaacgggc
    10441 atattgccgt attgttatcg acagatgaac ttagtggtgc agctgaggac actgatcgtc
    10501 tttacagatt ccaggtcaat ggtcgccctg acttaaacaa aatgcacacg gccattgata
    10561 tgggatcaaa taacctgaat aacgttgggg cagtaaatgc ccagacaggt aatttcagcg
    10621 gcaatgtgaa tggtgtaaat ggcactttca gcggtcaggt aaaaggcaat agcggaaact
    10681 ttgacgtaaa tgtcaccgct ggcggtgata tcagaagtaa taatggttgg ttaattactc
    10741 gtaacagtaa aggctggctc aatgaaactc acggtggcgg attttatatg tccgatggat
    10801 catgggttcg aagtgtaaac aacaagggca tctataccgg cggtcaggtg aaaggcggta
    10861 ctgttcgggc tgatggtcgc ctttatactg gtgaatactt acaactggaa agaactgccg
    10921 ttgctggcgc atcatgttcg cctaacggcc ttgtaggccg cgataataca ggggcaat
//
LOCUS       DAPHKZ010000143        10922 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.143, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000143 DAPHKZ010000000
VERSION     DAPHKZ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10922
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.143"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(40..498)
                     /locus_tag="RH288_003944"
     CDS             complement(40..498)
                     /locus_tag="RH288_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HDV4032950.1"
                     /translation="MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGR
                     IDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFA
                     NVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ"
     gene            complement(553..1404)
                     /gene="manZ"
                     /locus_tag="RH288_003945"
     CDS             complement(553..1404)
                     /gene="manZ"
                     /locus_tag="RH288_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020804907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HDV4032951.1"
                     /translation="MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSR
                     ITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     ACGLLGL"
     gene            complement(1417..2217)
                     /gene="manY"
                     /locus_tag="RH288_003946"
     CDS             complement(1417..2217)
                     /gene="manY"
                     /locus_tag="RH288_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDV4032952.1"
                     /translation="MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVAL
                     SVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD"
     gene            complement(2280..3251)
                     /gene="manX"
                     /locus_tag="RH288_003947"
     CDS             complement(2280..3251)
                     /gene="manX"
                     /locus_tag="RH288_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDV4032953.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETL
                     MARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPAAAAPKAAPTPAKPMGPND
                     YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTA
                     HVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQ
                     VNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK"
     gene            3714..5270
                     /gene="yoaE"
                     /locus_tag="RH288_003948"
     CDS             3714..5270
                     /gene="yoaE"
                     /locus_tag="RH288_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HDV4032954.1"
                     /translation="MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKAT
                     TELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQANVQHDADNPMPMPI
                     PEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQ
                     QALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIV
                     KEQPAHDEDE"
     gene            complement(5274..6872)
                     /locus_tag="RH288_003949"
     CDS             complement(5274..6872)
                     /locus_tag="RH288_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDV4032955.1"
                     /translation="MQKAQRIIKTYRRNRMIVCTICALVTLASTLSVRFISQRNLNQQ
                     RVVQFANHAVEELDKVLLPLQAGSEVLLPLIGLPCSVAHLPLRKQAAKLQTVRSIGLV
                     QDGTLYCSSIFGYRNVSVVDILAELPAPQPLLRLTIDRALIKGSPVLIQWTPAAGSSN
                     AGVMEMINIDLLTAMLLEPQLPQISSASLTVDKRHLLYGNGLVDSLPQPEDNENYQVS
                     SQRFPFTINVNGPGATALAWHYLPTQLPLAVLLSLLVGYIAWLATAYRMSFSREINLG
                     LAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGWISPDVFIPIAEEHHLIVPLTR
                     YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITE
                     RDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSD
                     AVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQGYLYAQPMPLRDFP
                     KWLAGSQPPPARHNGHITPIMPLR"
     gene            complement(7003..8367)
                     /gene="sdaA"
                     /locus_tag="RH288_003950"
     CDS             complement(7003..8367)
                     /gene="sdaA"
                     /locus_tag="RH288_003950"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDV4032956.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGR
                     HEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
                     AANEVSVPYPFKSATELLAYCNETGYSLSGLAMQNELALHSKKEIDEYFAHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            complement(8551..9129)
                     /locus_tag="RH288_003951"
     CDS             complement(8551..9129)
                     /locus_tag="RH288_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDV4032957.1"
                     /translation="MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQP
                     GLLLTQRSIHLRKHAGQVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLP
                     PVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
                     HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP"
     gene            complement(9133..10494)
                     /gene="pabB"
                     /locus_tag="RH288_003952"
     CDS             complement(9133..10494)
                     /gene="pabB"
                     /locus_tag="RH288_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HDV4032958.1"
                     /translation="MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYS
                     RFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPF
                     QGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV
                     NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRF
                     HATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGT
                     LPRLPDPQEDSKQAVKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPF
                     PAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCG
                     SIGYLSFCGNMDTSITIRTLTAINGQIFCSAGGGIVADSQEEAEYQETFDKVNRILKQ
                     LEK"
     gene            10568..10747
                     /locus_tag="RH288_003953"
     CDS             10568..10747
                     /locus_tag="RH288_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HDV4032959.1"
                     /translation="MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRAN
                     HSGERIVARFEDEDE"
     gene            complement(10867..>10922)
                     /locus_tag="RH288_003954"
     CDS             complement(10867..>10922)
                     /locus_tag="RH288_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1889 family protein"
                     /protein_id="HDV4032960.1"
                     /translation="NPEYFSTYMQEELKALV"
BASE COUNT         2732 a         2765 c         2783 g         2642 t
ORIGIN      
        1 taaaaataca ctaaacatag ctttggctaa attcataact tattgagttg aaacgagaag
       61 cttataaatt ttttccagat cgtcgatatt tcgaacgcgg attaacagcc gacgctgttc
      121 taattgcatc accaacacgc catcttccga caagttcatc gctttgattc ggctatattc
      181 aatccagaca ttggcgaaga aaaaaccttt ttgtttaaag atgatcttcg gaacgcggat
      241 ccagaatata taaaaaccca tcagagccag tgcgcttaat aaccatgtcg ttattaacgc
      301 accatgattc gtgacgttgt tatagataag aatgacaatc aatccgacga agataacgct
      361 atcgatgcga ccacgccgga gcaaaggaat tgccagcagg gtggggccgt tacggcgggg
      421 catgatgaac tgatcgtaga tcgcgaaggc caggagtgcg gcgatgaaaa gaatcagtac
      481 caggtccgtg attgtcatta atcctccaga taaaaaaacg gggccaaaag gccccggtag
      541 tgtacaacag tcttacagtc ccagcaggcc gcaagcgtaa ccagcgatac cgatgacgaa
      601 gaagccaacg atgatccaca gcgggttaac ttttttgcgc agtagccaca tacaagcaaa
      661 ggtcagcagc agtggtacca ggcctggcat taactggtcc agaatagtct ggacagtagt
      721 aacgtgttct ttgcccgtct ggtcagtaat gcgagagaca accagcggga tgttgacatg
      781 tgtccacttg ttaaccaatg cccccatgac aaacaggccg aggatagacg ccccttccgt
      841 cagtttttgc aggaagccac cacccatatc tttaacgata tcgatacctt tggagtaacc
      901 atacgctacg ccgtagtaac gggttgccag acgcaccagg ttaaacagga tgaagaacag
      961 cagcggacct aacaggctgc cgctcatcgc gataccggca cccagtgctg caaataccgg
     1021 acgtacggtt ccccagaaga tcgggtcgcc tacaccagcc agtggcccca tcaaaccgac
     1081 tttgataccg ttgatagcac cgtcgtcgat ctctgcgcca ttagcacgct gttcttccag
     1141 cgccagggtt acgccgagaa tcggcgcagc cacgaacggc tgggtgttaa agaactccag
     1201 gtgacggcga atagcttgtt tacgagcttc gttgttctca gggtagaggc gacgaattgc
     1261 cggtaccata gagaagcaga aacccagtgc ctgcatacgt tcgaagttcc atgaaccctg
     1321 gaagaggtta gaacgcagga agacgccacg aatatcactt tgagtgagtt ttttctcggt
     1381 ggtagtttga gttgtatcaa ccatttcgct cacctgttag tccagttcgt tatcgagatc
     1441 gttgttacca gctgcctgag caggcgcacc ggctacgcgg ttgtatttcg ggctaagttg
     1501 gatgtagagc actgccataa cagtaccaat cacacccaga gcaaccaggt taaagttggt
     1561 gaatgctgcg gttacgaagc cgaggtagaa gaacggcatc aggtagccag cacgcatcat
     1621 gttgataacc atcgcataac caaccaccac gatcatgcca ccggcgatat tcagaccatt
     1681 ggtcaccact tccggaatcg cattcagcat gttctgtact tcgctggtac caacagacag
     1741 cgcaacgatg acggccggaa tagccacacg cattgcttgc aggaacagag aagaaacgtg
     1801 gatccaggaa atcgctgtca ggttgccgtt atcagcagcc ttatccgcag cgtgctggaa
     1861 agcaacggta atagtacgaa cgatgatggt cagtacctgg cccgcagcgg ccagagggat
     1921 tgccagtgcg atacctgcac caatgctctg atgacctgcg ataaccagaa tggtagaaat
     1981 gatagaagcc agagcggcgt caggcgcaac tgcagcaccg atgttcatcc agcccagcgc
     2041 gatcatttcc agcgtaccac cgataataat accggttttc atatccccaa gaacgatacc
     2101 caccagggta cacgcgatta gcggacggtg aaactgaaat tcatcgagga ttgatcccat
     2161 acctgcgata caggctacga taaataccag cacaatttga agagtggtaa tctccattgt
     2221 acttctcctg tttacgtaag acttaagtgt gaaaactgag tgataatcaa cacaatacgt
     2281 tacttatcga ttttgctgat cagatccatc attttcagtt tcggatcggt ggaaacctta
     2341 cggacttcca gctcaatacc gcgcgcattc agtttcttga acgcctcgat atctttttca
     2401 tcaaccgaaa ccgcgttatt cacctgggtt ttaccctgac ggaatgccat accaccgacg
     2461 ttaacagagg tgattttcac gccgccttca acgagacgct ctacatctgt tgggttggta
     2521 aataacagca ttacgcgttc gccagcatat ttcgggttgt tgtagacgcg aatcattttg
     2581 gcaacatcaa ctacgtgtgc tgttacgccc ggaggtgcaa cctgggtgag cagtgtctta
     2641 cgaacggtat ccgcagccac ttcatcacta acaacaataa tacgggagac attggtttct
     2701 ttggtccagc gggtggcgac ctgaccgtga atcagacggt cgtcgatacg cgcaaggcca
     2761 ataaccatgt agtcgtttgg ccccattggt tttgccggag ttggagccgc ttttggtgct
     2821 gcggcagcgg gtgctggcgc ggctttttca accggtttgg ctttcagtgc tttcacgcct
     2881 tcacggcctg tttctactgc cagtgccacc agttcatcaa agcttgggtc atcatcacgg
     2941 gccattaacg tttccacgag cattggaatg ttaacgcctg caatgacttc ataatgctct
     3001 ttgtcgacga caatgcggct ggcagcattg aacgggctgc ctccccatgt atcaacgaga
     3061 aacagcacgc ctttagtggt gtcgagtttt gccaactgag cgttgtactt ttcaatcagc
     3121 gtttcggcat tttcacctgg aacgaaatcg atccagccga cgttttcctg ctcgcctaac
     3181 agcatttctg ccgttttaag caactgctct gcagcccaac catgtgtgcc tataacaata
     3241 gcaatggtca cttgctacct cctttattat cgttaacacc tcaacgtgcc agatgtattt
     3301 ttgaatcgtc gtccacaatc gaatcgattc agataagggc tacaaccaaa aacccctgcg
     3361 tttcgcgatt tattttagat atcgaaaaaa ttattttatg tgatgaagat ccgtaattta
     3421 actttcgatt agcagaaatt tcgaaaggta aaatatcctt gtcacattcg tttgcaaagg
     3481 aaggtaaatc tttgccaaat cagaggcgtc tctgatatgt ttaactcccg tttaacaacc
     3541 atggagtata gggcagtagc ccgcagtatg gatcgtcacc gacgtcattt cagcatcagg
     3601 ccttttaacg cctgcctttc tggcactcta tgccgcacct ttcgtttgca ttttgtcgtt
     3661 acgcctgcat tatttctggc gtcgaatagc tattccttaa gcaggagctt gtcatggaat
     3721 tcttaatgga cccctcaatt tgggcggggc tactcacgct tgttgttctc gaaattgtgc
     3781 tgggtatcga taacctggtc ttcatcgcca ttcttgctga caaactgccg ccaaaacaac
     3841 gcgataaagc gcgtttgctg gggttatcac tggcgctgat tatgcgtctg gggctgctgt
     3901 cgctgatttc atggatggtc acgctgacca aaccgctatt taccgtcatg gatttctcct
     3961 tctccggacg cgacctgatt atgttgttcg gggggatatt cttgctgttc aaagcaacaa
     4021 ccgaactgca tgaacggctg gaaaaccgcg atcatgattc cggccacggt aaaggctacg
     4081 ccagtttctg ggtggtcgtc acacagattg tcatccttga cgccgtcttc tcgttggatg
     4141 cggtaattac tgcagtaggg atggttaacc atctgccggt gatgatggcg gcggtagtga
     4201 ttgcgatggc ggttatgttg ctggcatcca aaccgctgac gcgattcgtt aaccagcacc
     4261 ccacggtggt ggtgctctgt ctgagcttcc tgttaatgat tggtctgagt ctggtggcag
     4321 aaggtttcgg tttccacatt ccgaaaggtt acctgtatgc cgcgattggc ttctcgatca
     4381 tcatcgaagt gtttaaccag attgcgcgtc gcaactttat tcgccaccag tcgactttgc
     4441 cgctgcgagc gcgtactgcc gatgccatcc tgcgtttgat gggcgggaaa cgtcaggcca
     4501 atgttcagca cgatgccgat aacccgatgc cgatgccgat cccggaaggt gcatttgccg
     4561 aagaagaacg ttacatgatt aacggcgtac tgacgctggc gtcgcgttct ctgcgcggga
     4621 tcatgacgcc gcgcggtgaa ataagctggg ttgacgctaa tctcggggtc gatgaaatcc
     4681 gcgagcaact gctctcttca ccgcacagtc tgttcccggt atgtcgcggt gaactggatg
     4741 aaatcatcgg tattgtacgt gctaaagaac tgctggtggc gctggaagag ggcgttgatg
     4801 tggcggcgat tgcttcggcg tctccggcga ttatcgtccc ggaaaccctc gatccgatca
     4861 acctgttggg cgtgctgcgt cgtgctcgcg ggagctttgt tatcgtgacc aacgagtttg
     4921 gtgtggtaca aggtctggtc acgccgctgg atgtgctgga agccattgcg ggtgaattcc
     4981 cggacgctga cgaaacgccg gaaatcatta ctgatggtga cggctggctg gtaaaaggcg
     5041 gtacagattt gcatgccttg cagcaggcgc ttgatgttga gcaccttgcc gatgacgatg
     5101 atatcgcgac ggtcgcgggc ctcgtgatct cggcaaatgg tcacattccc cgtgtgggcg
     5161 atgtgattga tgtagggcca ctgcatatca ccatcattga agccaatgat tatcgtgttg
     5221 atctggttcg cattgttaaa gagcaaccgg cgcacgatga agatgagtaa gcgttaacgt
     5281 aacggcataa tgggcgtgat atgtccatta tgccgggcgg gcggcggttg gctgcccgcc
     5341 agccatttgg gaaaatcacg tagcggcatc ggctgtgcgt acaaataccc ttgcaaaata
     5401 tgcacgccat gacggcgcaa atacttcgcc tgttcttgcg tttccacgcc ctccgccacc
     5461 agttcaatat tcagtctttg ccccagcgcg atgatgatat cggtcaccgt cgagttaacc
     5521 gcgtcagaac ctatagctgc ggtaaatgac ttatcaattt tcagcacgtc aggacgtaat
     5581 gtttcaagcc aggaaaacga gctgttgccg gtgccgaagt catcaatcgc cagtttgacg
     5641 tttttacgat gcagctcgcg ggcaatccga taatcaacat ccagtaaggc atcgcgttcg
     5701 gtgatttcga ggatcagttg ctgaatcggg tgagcgctaa accagtactg attgagatct
     5761 tttatcagca caccacggcg aaaatggctg ggtgcgacgt taatgccaac atgaaactga
     5821 ctactcatcg ggaaaacatg gcgctgacga atggtttctg ccatcacata gcgggtcagt
     5881 ggcacaatta aatgatgttc ttccgcgata ggaataaaca catccggtga aatccagccc
     5941 tgacgcggat tgttccagcg cagcaaaatc tctacaccaa tacattgctg gctgcgcgca
     6001 ttaagcaaag gctgacagaa caattcgaac tcatgttgcg ccaggcccag attgatttcg
     6061 cgggaaaagc tcattcggta agcggtcgcc agccaggcga tgtagcccac cagtaaactt
     6121 agcagcaccg ccagcggtaa ttgtgttgga agatagtgcc atgccagcgc cgtagccccc
     6181 ggaccattaa cgttaatggt aaaaggaaag cgttgcgaag aaacctgata gttttcattg
     6241 tcttcaggtt gcggaaggga atctaccagc ccattaccat agagcaaatg ccgtttgtcc
     6301 accgtcaggc tggcgctact gatttgcggc agttgtggct caagcagcat tgccgtcagt
     6361 aagtcgatgt taatcatctc catgacccca gcattgctac tgcccgctgc aggcgtccat
     6421 tgaatcaaaa ccggactgcc tttaatcagg gcacggtcga tcgtcaggcg taaaagtggt
     6481 tgcggtgcag gaagttcagc cagaatgtcc acgacggaca cattgcgata accaaaaatg
     6541 ctggagcaat aaagtgtgcc gtcttgcacc aggccaatgg atcgcacagt ttggagtttt
     6601 gccgcctgtt tacgtaatgg caaatgggcg acagagcagg gcagaccaat cagcggaagc
     6661 aagacttcgc tacctgcctg taggggaagc agtactttat ctaattcctc tacagcgtga
     6721 ttggcgaatt gtactacccg ttgttgattt aagttacgct gtgaaataaa tcgcacgctc
     6781 agggtcgaag cgagcgtaac gagtgcgcaa atcgtacaaa caatcattcg attacgacga
     6841 taggttttaa tgatccgttg tgctttttgc atgcgggcca ccctgtaagc gtatggcgac
     6901 aaacgcctga cgcaacagtg gaagtgtagt ggggaatatt acagcagacg agaaagcggg
     6961 tataaattcg cccatccgtt gcagatgggc gagtaagaag tattagtcac actggacttt
     7021 gattgccaga ccaccgcgtg aggtttcgcg gtatttggcg ttcatgtcct taccggtttc
     7081 gtacatcgtt tcgatgacct tatccagcga gacgcgcggt gcactggtgc ggcgcagagc
     7141 catccgcgcg gcgttaatcg ccttcacaga ggcaatggca ttacgctcaa tgcacggcac
     7201 ctgaacctgc cctgcaaccg ggtcgcaggt taaaccaagg ttgtgttcca tgccaatttc
     7261 cgccgccacg caaacctgtt ccgggctacc gcccagcagt tctgcaagac ccgcagcagc
     7321 cattgaacag gcaacaccca cttcgccctg gcaaccaact tccgcaccgg aaatagaggc
     7381 gttcatttta tacaatgcac caatcgcgcc cgctgccata aagtaacggg tatagatgtc
     7441 cgggctgacc gattcaataa agtggtcata gtaagccagc actgccggaa cgataccgca
     7501 ggcaccgttg gttggcgcag ttaccacacg accaccggcg gcgttttctt cgttaactgc
     7561 cagcgcaaac atgtttaccc agtcaatgac attcatcgga tcgttagaca gtttatcgct
     7621 ggaaaccagc atccggcgca gggcagacgc acgacgtggc acgcgcagcg ggcctggcag
     7681 tacaccttcg gtgttcatcc cgcgatcgat acatgcctgc atggtttgcc agacatgcgc
     7741 gaaatactcg tcgatctctt tcttgctgtg cagcgccagt tcgttctgca tagcgagacc
     7801 agacagcgaa tagccggttt cattacagta cgcgagcagt tcggtggcag atttgaacgg
     7861 atacggcacg cttacttcgt tggcagcatc ctgaccaaag tgttcttcat cgacgataaa
     7921 accgccgccg atggaataat aagttttgct gtagacgact tcatcgccgt tataggcgtg
     7981 gatttgcata ccgttttcat gcagcggcag gttgccgtta tgaaaacgca tcccgttgtc
     8041 gcgcgggaaa tccacttcat gccgtccctg tgccagcagc agacgttcgc gctcttctac
     8101 gtcgcgaata aaaccgggaa tactgtcgat atccacggtg gcaggttcgt tacctgcaag
     8161 acccataata atggcgatat cggtgtggtg gcctttaccc gtcagcgaca gtgaaccata
     8221 aacgtccacg gcaacgcgag taacgctatc cagtaagcct ttttcgacca gatcatcgac
     8281 gaactgttta cctgccttca taggccctac ggtatgggaa gatgagggac caatccccac
     8341 cttaaacatg tcgaatagac taatcacgat aatactcctg acaaggtgac tggacttcca
     8401 gtaacgaact aataacagcg catagtgtaa gagggaacgc ggcgactggc ttaactattc
     8461 acatgaatta aactaatcaa aaaccgcgat ttaactaata ttgcgatgat tgtctcaagt
     8521 agtgttttgt agatgtaaag ataagtatag tcagggtttc acaccaattt gcagcgccag
     8581 ctcacgaatt atgcctgcgg tcattcccca tacaaaatac tgttcgtacc aggacagcca
     8641 tacccgatgt gaatcaccac ggcggtagat atctaaaggg tgataacgac ccagatgtaa
     8701 tgcctgggcg agcggcattt caaacaccgc cgagacttca tcttcactgg cgcgatacgg
     8761 cagatcgggc gggataatgc cgaccactgg ggttacctgg tagccagtga cgctatcgac
     8821 gggcggcagc acgccgataa cttcaacggc ggaaggcggt atagcgacct cttcttcagc
     8881 ttcgcgcagc gcggcggcga tagctgatgc gtccgtgtca tcgactgcac ctccagggaa
     8941 tgccacttgt ccagcgtgtt tacgcagatg aatcgaacgc tgagtcagca acaaccccgg
     9001 ttgcggtcga cggacgatgg ggattaacac agcagcctga cgatgattta gggtttcccg
     9061 gttaatttgc gggcgcaaaa gttgaaagcg cgataaaaaa tcatcaagcg tcaggctacg
     9121 gtattccacg tcttacttct ccagttgctt caggatacga ttaactttat caaaagtttc
     9181 ctgatattcc gcttcttcct ggctatcggc gacaattcca ccgcccgcag agcagaaaat
     9241 ttgtccgtta atggcagtca gcgtgcggat agtaatactg gtatccatgt tgccgcaaaa
     9301 gctcaaatag ccaatgctgc cgcaccaggc attgcgtcgc tgcggttcca gttcgtcgat
     9361 aatttccata gcccgtactt tcggagcccc ggttattgag ccaccaggaa aagctgcgcg
     9421 cagcagatcg ctggcgtgta actgttctgg tagttgcgcc gttatggtgc tgaccagatg
     9481 atgcacggca gggaagggtt ccaccacgaa cagctctggt acttttaccg aacctgctac
     9541 ggcaacacga ccgatatcat tacgcattaa atcgacaatc atcagatttt cggcacgatc
     9601 tttcgctgag ttcgccagtt ttactgcttg tttgctatct tcctgaggat cgggcaggcg
     9661 tggtagcgtg cctttaatcg ggcgggtctg gatttcacta ttatcacaaa gaataaaccg
     9721 ctctggcgaa aggcttaaaa ttgcaccctg ttcaagacgt aaaaaagcgc taaatggcgc
     9781 gcggttggcc tgattaagct gaaggaatgc ctgccattca tcgccagaat aggtcgcatg
     9841 aaaacgttgg gcgagattca cctgatagca atcaccgctg tgcagatatt cctgtacctg
     9901 gcgaaatttt tcgccgtact gctcgcgggt catattggat tgccagtcgg aagtgagcgt
     9961 gaaatcttcc tgcggcgaga attgctggct ttccagccag gcccgacggg cattgacatc
    10021 attatgactc agcaaagaaa ctgtatgacg ctggtggtcg acaatgagcg cccaatcgta
    10081 gatacccact gccatatccg gcagaacgat atcttgttcc gcaatttctg gcagtgactc
    10141 aaaacggcgg cccagatcgt agccaaacaa ccccagtgcg ccgccctgaa atggcaaatc
    10201 ttcgttatgc gttgggcgaa tgtctgcgcg atccagcacc tgctggagca cctgtagcgg
    10261 gtcatcagtg gtcgttgtgc gtttttcgct ttcactaaca acggtttctt taccgaaagt
    10321 ggttaaagtg caaatcggct cggcgaccac aatatcaaag cggctatacg gatgatcggc
    10381 atagccggag tgtaaaagca tcgcccacgg caggtggctt aagcgggaga aataaaattc
    10441 agcggcgtcc tgacgccagg gtaaagtaat cacagcggga gataacgtct tcatcagtcc
    10501 tgactctact ggctatgtgc cgggtagcat gaaataatta gcgccaacaa tttagcagga
    10561 gttaacaatg tttgcaggtt taccttcact cacccatgaa cagcagcaaa aagctgtcga
    10621 gcggatccag gaactgatgg cacaagggat gagcagcggc caggcaatcg cgctggtggc
    10681 agaagagctg cgtgccaacc actccggcga gcgaatcgtg gcgcgttttg aggatgaaga
    10741 cgagtaacac actaatccgt atcgatttcg ttatagaagc cgatgatcat ttgattgtga
    10801 gaaaaaggac gctttttata tgtgattaaa agcgtcctga cccatttatg ctgatataaa
    10861 tttaactcag accagtgctt ttagttcttc ctgcatatat gttgaaaagt attcaggatt
    10921 tt
//
LOCUS       DAPHKZ010000144        10892 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.144, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000144 DAPHKZ010000000
VERSION     DAPHKZ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10892
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.144"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            51..812
                     /gene="adiY"
                     /locus_tag="RH288_003955"
     CDS             51..812
                     /gene="adiY"
                     /locus_tag="RH288_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator AdiY"
                     /protein_id="HDV4032961.1"
                     /translation="MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNI
                     IDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVWQRSATPILTLPCLTPDVFRVAA
                     QHSMMPAETESEKERTRALLFTVLSRFLDSKKFVSLMMYMLRNCVSDSVYQIIESDIH
                     KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQ
                     SCGYNSTSYFISVFKDFYGMTPLHYVSQHRERTVA"
     gene            949..2286
                     /gene="adiC"
                     /locus_tag="RH288_003956"
     CDS             949..2286
                     /gene="adiC"
                     /locus_tag="RH288_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HDV4032962.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIY
                     GWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
                     PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILM
                     TIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTT
                     IAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD"
     gene            2390..4033
                     /gene="eptA"
                     /locus_tag="RH288_003957"
     CDS             2390..4033
                     /gene="eptA"
                     /locus_tag="RH288_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HDV4032963.1"
                     /translation="MLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDS
                     LHNVLVFLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDR
                     SMIANIIDTTPAESYALMTPQMLLTLGFSGVLAALIACWIKIKPATSRLRSVLFRGAN
                     ILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVR
                     IGEDAHRNPLMQNEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTA
                     SCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACD
                     RVPHQNVTALNLPDQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYYNR
                     YPPQFRKFTPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSL
                     VYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQ
                     TQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE"
     gene            4030..4698
                     /gene="basR"
                     /locus_tag="RH288_003958"
     CDS             4030..4698
                     /gene="basR"
                     /locus_tag="RH288_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BasR"
                     /protein_id="HDV4032964.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGH
                     YSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVA
                     NEEN"
     gene            4699..5799
                     /gene="pmrB"
                     /locus_tag="RH288_003959"
     CDS             4699..5799
                     /gene="pmrB"
                     /locus_tag="RH288_003959"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HDV4032965.1"
                     /translation="MNLMHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQI
                     QLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQ
                     KELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
                     LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLE
                     DVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGS
                     NIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQL
                     HHGQFFLQNRQETSGTRAWVRLKKDQYVANQI"
     gene            complement(5775..5864)
                     /gene="pmrR"
                     /locus_tag="RH288_003960"
     CDS             complement(5775..5864)
                     /gene="pmrR"
                     /locus_tag="RH288_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HDV4032966.1"
                     /translation="MKNRVYESLTTVFSVLVVSSFLYIWFATY"
     gene            complement(5976..7478)
                     /gene="proP"
                     /locus_tag="RH288_003961"
     CDS             complement(5976..7478)
                     /gene="proP"
                     /locus_tag="RH288_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HDV4032967.1"
                     /translation="MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLTCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVA
                     LFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGAT
                     PAASDIQEAKEILVEHYDNIEQKIDDIDHEIADLQAKRTRLVQQHPRIDE"
     gene            complement(7742..8620)
                     /locus_tag="RH288_003962"
     CDS             complement(7742..8620)
                     /locus_tag="RH288_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418534.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcZ-like family protein"
                     /protein_id="HDV4032968.1"
                     /translation="MTKTLLDGPGRVLESVYPRFLVDLAQGDDARLPQAHQQQFRERL
                     MQELLSRVQLQTWTNGGMLNAPLSLRLTLVEKLASMLDPGHLALTQIAQHLALLQKMD
                     HRQHSAFPELPQQIAALYEWFSARCRWKEKALTQRGLLVQAGDQSEQIFTRWRAGAYN
                     AWSLPGRCFIVLEELRWGAFGDACRLGSPQAVALLLGDLLEKATQHLAESINAAPTTR
                     HYYHQWFASSTVPTGGEHADFLSWLGKWTTADKQPVCWSVTQRWQTVALGMPRLCSAQ
                     RLAGAMLEEIFSVNLA"
     gene            complement(8617..10845)
                     /gene="crfC"
                     /locus_tag="RH288_003963"
     CDS             complement(8617..10845)
                     /gene="crfC"
                     /locus_tag="RH288_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="clamp-binding protein CrfC"
                     /protein_id="HDV4032969.1"
                     /translation="MYTQTLYELSQEAERLLQLSRQQLQLLEKMPLSVPGDDAPQLAL
                     PWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPM
                     TALPTLIRHTPGQKEPVLHFSHVAPIDCLIQQLQQRLRDCDIKHLTDVLEIDKDMRAL
                     MQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVE
                     FVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISD
                     EEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVS
                     SMWGYLANRARYELANNGKLPPPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQ
                     LWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQ
                     LRQNIHQIEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDALKVQLAALFQD
                     DSEPLSEIRTRCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQVKMELS
                     ESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQEATDEQSTRLGVVRETFSRWLNQPD
                     WGRGNEKSPTETVDYSVLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFAS
                     CLTELQTRLRESLALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAE
                     RY"
BASE COUNT         2729 a         2848 c         2686 g         2629 t
ORIGIN      
        1 gctttgcttt agcgagaact ggtcttttat tcgcactcag gagtacatgt atgaggattt
       61 gcagcgacca accttgtatt gttttattga ctgaaaaaga tgtctggata agggtgaatg
      121 ggaaagaacc tattagcctt aaagctaacc atatggcgtt attaaattgt gaaaataata
      181 ttatcgacgt ctcctctctt aacaacactt tggttgctca tattagtcac gacatcatca
      241 aagattacct ccggtttctg aataaagatc tctcgcaaat accagtatgg caacgtagcg
      301 ctacgcccat actcaccctg ccatgcctga cgccagacgt ctttcgcgtt gccgcgcaac
      361 acagcatgat gcccgcagaa actgagtcag aaaaggaacg aacacgcgca ttattattca
      421 cggtgctatc ccgttttctc gacagtaaaa aattcgtttc attaatgatg tatatgttac
      481 gtaattgtgt aagtgacagc gtttatcaaa ttattgaaag cgatattcac aaagactgga
      541 atcttagtat ggtagccagt tgtttatgtc ttagcccaag tctgttaaag aaaaagttga
      601 aaagcgaaaa caccagttat agccaaataa tcaccacctg ccgcatgcgt tatgccgtaa
      661 atgaattaat gatggacggt aaaaatatct ctcaggtatc acagtcctgc ggctacaaca
      721 gtacgtcgta ctttatttct gtctttaaag acttctacgg tatgacgccg ctgcattatg
      781 ttagtcagca cagagaacgc actgtcgcct gatttttaac cttaacgaag agctatatta
      841 ataacggcat cagcgataac ccggtcgata ataattcaac tatcgaatgc aggcgtatga
      901 tatgacgtaa tttattgtca cgaagctcgc cttcgcagga gtttaattat gtcttcggat
      961 gctgatgctc acaaagtggg cttaatcccc gtcaccctga tggtgtcggg gaatattatg
     1021 gggtcaggtg tttttctgtt acctgcaaac ctggcctcta ctggcgggat tgccatttat
     1081 ggatggttgg tgacgattat cggtgcactg gggctctcga tggtatacgc caaaatgtcg
     1141 ttcctcgacc caagtcctgg tggttcttac gcttacgccc gccgctgctt tggcccgttt
     1201 ctcggttatc aaaccaacgt cctctactgg ctggcctgct ggatcggcaa tatcgccatg
     1261 gtggtcattg gcgtaggata tttaagttac ttcttcccga ttctgaaaga tccattggta
     1321 ttaaccatca cctgcgtcgt ggtgctgtgg atcttcgtcc tgctgaacat tgtcggtccg
     1381 aaaatgatca cccgtgtgca ggcagttgcc accgtgctgg cgctgatccc catcgtcggg
     1441 attgccgtat ttggctggtt ctggttccgt ggtgaaacct atatggcggc atggaacgtc
     1501 agcggcctgg gcaccttcgg tgcaattcaa agtaccctta acgttacgct gtggtcgttc
     1561 atcggtgtgg aaagtgcctc cgttgccgca ggtgtggtga aaaacccgaa acgcaatgtc
     1621 cctatcgcca ccattggtgg ggtattgatt gccgccgttt gctatgtact ttctaccacc
     1681 gcgattatgg ggatgatccc taatgccgca ctgcgcgttt ctgcttcgcc attcggtgat
     1741 gccgcacgga tggcgttggg tgacaccgcc ggggccattg tttccttctg cgcagctgcg
     1801 ggttgcttag gttcactggg cggctggacg ttgctggcgg gtcaaacggc gaaagccgct
     1861 gccgatgacg gactgttccc accgattttt gcccgtgtaa ataaagcggg tacgccagtg
     1921 gcggggctga ttatcgtcgg tattttgatg accatcttcc agctcagcag catttcacca
     1981 aacgcgacca aagagttcgg tctggtttct tccgtctcgg tcatctttac actggtgcca
     2041 tatctttaca cctgtgcggc gttactgctg ctcggacacg gtcactttgg taaagcacgc
     2101 ccggcatatc tggcagttac taccattgcc ttcctctact gcatctgggc cgtggtgggg
     2161 tccggagcga aagaggttat gtggtcattt gtcaccctga tggtcatcac cgccatgtat
     2221 gcgctgaatt acaaccggct acataaaaac ccgtatccct tagatgcacc aataagcaaa
     2281 gattaattcc ccttaatcca gcaaacataa aagccaacct taagaactta aggttggctt
     2341 aattttgctt tgcgagcata tgcgcacttt gttcgatgga aacaccgtga tgttgaagcg
     2401 cctactaaaa agaccctctt tgaatttact cgcctggcta ttgttggccg ctttttatat
     2461 ctctatctgc ctgaatattg ccttttttaa acaggtgttg caggcgctgc cgctggattc
     2521 gctgcataac gtactggttt tcttgtcgat gccggtcgtc gctttcagcg tgattaatat
     2581 tgtcctgaca ctaagctctt tcttatggct taatcgacca ctggcctgcc tgtttattct
     2641 ggttggcgcg gctgcacaat atttcataat gacttacggc atcgtcatcg accgctcgat
     2701 gattgccaat attattgata ccactccggc agaaagttat gcgctgatga caccgcaaat
     2761 gttattaacg ctgggattca gcggcgtgct tgctgcgctg attgcctgct ggataaaaat
     2821 caaacctgcc acctcgcgtc tgcgcagtgt tcttttccgt ggagccaata ttctggtttc
     2881 tgtactactg attttgctgg tcgccgcact gttttataaa gactacgcct cgttgttccg
     2941 caataacaaa gagctggtga aatccttaag cccctctaac agcattgttg ccagctggtc
     3001 atggtactcc catcagcgac tggcaaatct gccgctggtg cgaattggtg aagacgcgca
     3061 ccgcaacccg ttaatgcaga acgaaaaacg taaaaatttg accatcctga ttgtcggcga
     3121 aacctcgcgg gcggagaact tctccctcaa cggctacccg cgtgaaacta acccgcggct
     3181 ggcgaaagat aacgtggtct atttccctaa taccgcatct tgcggcacgg caacggcagt
     3241 ttcagtaccg tgcatgttct cggatatgcc gcgtgagcac tacaaagaag agctggcaca
     3301 gcaccaggaa ggcgtgctgg atatcattca gcgagcgggc atcaacgtgc tgtggaatga
     3361 caacgatggc ggctgtaaag gtgcctgcga ccgcgtgcct caccagaacg tcaccgcgct
     3421 gaatctacct gatcagtgca tcaacggcga atgctatgac gaagtgctgt tccacgggct
     3481 tgaagagtac atcaataacc tgcaaggtga tggcgtgatt gtcttacaca ccatcggcag
     3541 ccacggtccg acctattaca accgctatcc gcctcagttc aggaaattta ccccaacctg
     3601 cgacaccaat gagatccaga cctgtaccaa agagcaactg gtgaacactt acgacaacac
     3661 gctggtttac gtcgactata ttgttgataa agcgattaat ctgctgaaag aacatcagga
     3721 taaatttacc accagcctgg tttatctttc tgaccacggt gaatcgttag gtgaaaatgg
     3781 catctatctg cacggtctgc cttatgccat cgccccggat agccaaaaac aggtgccgat
     3841 gctgctgtgg ctgtcggagg attatcaaaa acggtatcag gttgaccaga actgcctgca
     3901 aaaacaggcg caaacgcaac actattcaca agacaattta ttctccacgc tattgggatt
     3961 aactggcgtt gagacgaagt attaccaggc tgcggatgat attctgcaaa cttgcaggag
     4021 agtgagtgaa tgaaaattct gattgttgaa gacgatacgc tgttattgca gggactgatt
     4081 ctggcggcgc aaaccgaagg ctacgcgtgc gatggcgtga caaccgcgcg gatggcggaa
     4141 caaagccttg aggcaggtca ttacagcctg gtggtactgg atttagggtt acccgacgaa
     4201 gatggactgc attttctcgc ccgtatccgg cagaaaaaat ataccctgcc ggtactgatc
     4261 ctcaccgctc gcgatacgct gaccgacaaa atcgccgggc tggatgtcgg tgccgacgac
     4321 tatctggtga agccttttgc gctggaagag ttacatgccc gtatccgcgc cctgctacga
     4381 cgccataata atcagggcga aagtgagctg attgttggca atctgacgct gaacatgggt
     4441 cgccgtcagg tatggatggg cggtgaagag ttgattctga cgcccaaaga atatgctctg
     4501 ctgtcacggt taatgctcaa agcaggcagt ccggtgcatc gggaaattct ctacaacgac
     4561 atctataact gggacaatga accctcgacc aacaccctgg aagtgcatat ccacaatctg
     4621 cgcgacaaag tgggcaaagc ccgtatccgc accgtgcgcg gctttggcta tatgctggtc
     4681 gcgaatgagg aaaactaatt gaatctgatg cattttctgc gccgaccaat atcgctgcgc
     4741 caacggctga tattgaccat cggggccatt ttgttggtgt ttgagctgat cagcgtcttc
     4801 tggctatggc atgaaagtac cgagcagatt cagctgtttg agcaggcgct acgcgacaat
     4861 cgcaacaacg atcgccacat catgcgtgag atccgcgagg cggtcgccag cctgattgtc
     4921 cccggcgtct ttatggtcag cctgacgcta tttatctgct atcaggcggt acgccgcatc
     4981 acccgcccgc tggcggagct gcaaaaagag ctggaagcgc gcaccgccga caacttaacg
     5041 cccattgcca ttcacagcgc caccctcgaa atcgaagcgg tggtttcggc gttaaacgat
     5101 ctggtcagtc gcctgaccag cacgctggat aacgaaaggt tgtttaccgc tgacgtcgcg
     5161 cacgaactgc gaacgccact ggcgggggtg cgtttgcatc tggaactgct ggcgaaaacg
     5221 catcacattg atgtagcacc gttagtggca cggcttgatc agatgatgga gagcgtctcc
     5281 cagctgctgc aactggcgcg tgccggacag tcattttctt ccggtaatta tcaacatgta
     5341 aaactgctgg aagatgtcat tctcccctcg tatgacgaac tcagtaccat gctcgaccag
     5401 cgacagcaaa ccctgctatt gccagagagc gccgccgaca tcaccgttca gggtgatgca
     5461 accctgctgc ggatgttatt gcgaaacctg gtagaaaacg cccatcgtta cagcccgcaa
     5521 ggcagcaaca ttatgattaa gctgcaagaa gatgacggag cggtcatggc agttgaagat
     5581 gaaggaccag gtattgatga gagtaaatgc ggggagttga gtaaagcgtt tgtacgtatg
     5641 gacagccgtt atggcgggat tggtctgggg ttaagtattg tcagccgcat tacacagttg
     5701 catcacgggc agtttttcct gcaaaaccgg caagagactt ccggcacgcg ggcctgggta
     5761 cggctgaaga aagatcagta cgtggcaaac cagatataaa gaaagctgct gaccaccagc
     5821 acgctgaaca cggtagttaa actttcataa acacggtttt tcattgcact ctcctccgtt
     5881 aacctggagg agagtatgcg cgtcagagat taagtgaacc ttaagagttc aattggcctg
     5941 ataagacagc gtcacatcag gccatccgtt tcagcttatt catcaattcg cggatgttgc
     6001 tgcaccaggc gggtacgttt cgcctgcaaa tcggcaatct cgtggtcaat atcatcgatt
     6061 ttctgctcga tattatcgta atgctcgacg agaatttcct tcgcttcctg tatatctgac
     6121 gccgccggtg tcgcaccttt caacggacga tttgccgtct ctttcatggt tacgccggtg
     6181 attaaaccaa ccaccgccac taccatcagg taataggcag gcatcatcag attctgcgag
     6241 ctttcgacca gccaggccgc cagcgttggc gtcagaccgg caaccagcac cgaaatatta
     6301 aatgccgccg ccagcgcgct gtaacggata tgcgtcggga acatcgctgg caaggtagaa
     6361 gccataacgc ccgtaaagca gttaaggatc accgccagca tcagtaaccc ggcaaaaatc
     6421 aggccgatga cgttactgtt aatcagaata aacgccggga tcgccaacac aaacagggca
     6481 acactaccaa gtagcacaaa cggacgacgg ccaaaacggt cactcagcaa gcccatcacc
     6541 ggctggacaa acagcatacc gatcataatg gcgataataa tcagcacccc gtggtcttcg
     6601 gagtaatgca ggttatgcga caaataactc ggcatatagg tcagcaacat gtagtaagtc
     6661 acgttggtgg caattaccag accaatacat gtcaacaggc tgcgccagta tttagtggca
     6721 atctctttaa acgagacttt cgggccatcc tgcaaacctt cacggtcgcc ctgttccagt
     6781 ttatcgacat gctgctggaa cgccggagtc tcttccagcg catggcgcag gtaaagcccg
     6841 ataatcccta acggcagagc gataaagaac ggaatacgcc agccccaatc gaggaagttc
     6901 gcttcgccga caatggtcga aattaacacc accacgcccg cacccagcac aaacccggca
     6961 atagaaccga agtccagcca gctgcccata aagccacgtt tacggtcagg ggagtattcc
     7021 gcaacaaata tcgacgcccc ggtatattca ccgccgaccg agaaaccttg tgccatctta
     7081 cagatcaaca gcagaatcgg tgcccaaata ccaatcgtgt cgtaggacgg tattaagcca
     7141 atacagaacg tactgatcga cataatcaca atagtgatag cgaggatctt ctggcgacca
     7201 tatttatcgc ccaacatacc aaagaagagt ccgccaagcg gtcgaatcag aaagggaacg
     7261 gagaaagtgg caagtgcagc aaccatctgc acgctggggt cagcccccgg gaaaaaaact
     7321 ttacctaatg cgtaagcaac aaaaccataa acaccaaaat cgaaccattc cattgcatta
     7381 cccagtgatg ctgcggtaat ggctttacgc agtttaccgt catcaataat ggtgacatca
     7441 cgaagggtaa tcggttttac ttttttcctt ttcagcatag ctttcctcgc agagttggcc
     7501 catttccgca aacgccagaa aaatcagcgc gacggccgca aaaggggagc gggaattgca
     7561 ggatgcaatc tctgtaacaa gcgtagcggg tttgcttaca ccctccggtt aaggaatgta
     7621 caatcaaacc agttgacgcc tgaattgggc agttaatgac ctttttaccc taccagtgtt
     7681 taaatttgtg atcaacttca cacatggatt tcgtttagga ctcattgatg taactgatta
     7741 tttacgccaa atttacagag aagatttcct cgagcattgc ccccgccaga cgctgcgctg
     7801 aacagagtcg tggcatcccc agcgcgacag tttgccagcg ttgggtcact gaccagcaaa
     7861 cgggttgttt atctgccgtg gtccactttc ccagccaact taaaaaatca gcatgctccc
     7921 cgcccgtcgg aacggtcgaa gaggcaaacc actgatggta atagtgacgc gtggtcggtg
     7981 ccgcattgat actctctgcc agatgttgtg tcgctttctc gagcaaatca cccagcaaca
     8041 acgccaccgc ttgcgggctt cccagacggc aggcatcgcc aaatgccccc cagcgcaact
     8101 cctccagaac gataaaacag cgcccaggca acgaccaggc gttatacgcc ccagcacgcc
     8161 agcgggtaaa aatttgctcg ctctgatcac ctgcctgcac cagtaggcct cgttgcgtta
     8221 acgccttttc cttccagcga caacgggctg aaaaccactc atacaaggcg gcaatttgct
     8281 gggggagctc cgggaaagca gagtgctggc ggtgatccat tttttgcagc agcgccagat
     8341 gctgcgcgat ctgcgtcagt gccagatgac cgggatccag catcgacgcc agtttttcca
     8401 ccaatgtcag acgcaggcta agcggcgcat ttaacatgcc gccgttcgtc catgtctgaa
     8461 gctgcacacg cgaaagaagt tcctgcatca gtcgttcacg aaactgctgc tgatgggctt
     8521 gtggaaggcg ggcatcatca ccctgcgcca gatccactaa aaagcgggga taaaccgact
     8581 ccagcacgcg accggggccg tcaagtaacg tcttggtcaa tatcgttctg ccgtgaaaag
     8641 tgtttgaata tcatcgcgta acagctgggc gtcggtgtaa atccagccgt gagtcatcac
     8701 agtctgctgc aattgctgct gcatcagcct gaccaccgat tcattttgtt gacgcagagc
     8761 cagactttcg cgtaaacgcg tctgtaattc cgtcaaacat gaagcgaact cagcgaaaaa
     8821 agtattcatg cctgccgtaa cagattcatc gacctgctct gccagaactt tagccatttg
     8881 ttggcaatag agatcgactt ctgcgcttaa tgctcgttgc aacacactgt aatcaaccgt
     8941 ttctgtcggt gatttctcat ttccccgtcc ccagtcgggc tgattcaacc agcgcgaaaa
     9001 agtctcacgc acaacgccta aacgcgtgct ctgctcgtcc gttgcttcct ggcgcgaaat
     9061 gacttcactg aacagctggc gagtgttgaa gtggggaact acgccgtgaa aaacaggaaa
     9121 atgaaaccca ggacgaaacc ctgactcgct caattccatt ttgacttgtt gctcaatggg
     9181 gcgaataaca tcggttaaca cccggcaaag ggtggattca agctcggcaa aacgcagcgt
     9241 aaagtcgcga ctgatggtgt tctgcgccgt ctgtaacagt gtctcacagc gggtacgaat
     9301 ctcgcttaac ggctccgaat catcctgaaa caaggcggct aactgcacct tcagcgcatc
     9361 ttgctgttga cgcagaaagt ggttggcgga ggtcagggcc agctcgattt catgtttaat
     9421 ctcgccgctc acctgcgcct gattgagttg caatagctgc aaactttctt cgatctggtg
     9481 gatattttgc cgcaattgtt cacaagcgac gtttaacccg tgcgcacgaa aatccaggta
     9541 ttcccgcgcc tgctgcgcgt aattcaacag tttatgcgcg gcagatcgca gagcatacaa
     9601 cgaggcgtta gcgtaagcgg catgaagcaa cgcctgaatt ggctgggcga acagcgaatc
     9661 ttcccacaac tgatcggcag catgacgaat atgttcgagg tccgccagat cggcatgacg
     9721 ccagcgcctg ccaagcgcgg catgggcaaa atcttccacc cagcgttgtt gctctggcgg
     9781 tggtaactta ccgttgttgg ctaactcata gcgcgcccga ttcgccaggt agccccacat
     9841 cgacgacacc ggaaatatct gctgtggcgt aatacagcct ttcatcagcg tcccggaaat
     9901 cagtgcccgc acctggtcgg cgtcgtcact gttacgatcc tgttgatcga acttattgac
     9961 cagcacgtac agcggcaccg attgccccac cgccaaaatc gcctcacgga cctcttcatc
    10021 ggagatcgat ttcagttgcg tataatccag caccgccagt accgccgagg cgcgtgccag
    10081 ctgctggtta agcatttttt gcagatgcgg ttgcccggct tcatttggcc cgggggtatc
    10141 cagtaacgtc aactgaccgg gataactctc cagccccgct agatggacaa actccacttc
    10201 aatcacggga atatgctcaa tggcggcgta agcagaaaaa ggaaaatcga cgtccagcgc
    10261 cttcgccagt cgcactaaat cattcaaact tttcagacaa tgaaaaatag gctgggcacc
    10321 cagataatat ttttcgaaag cgacgccatt ttcgatccgc tgcataagcg cacgcatatc
    10381 tttatctatt tccagcacat cggtcagatg cttaatatcg caatcacgca ggcgctgttg
    10441 taattgttga attaaacaat cgattggcgc gacatgtgaa aaatgcagta ccggttcctt
    10501 ttgcccgggc gtatggcgaa taagcgtcgg cagcgcagtc attgggcgat tacgattagg
    10561 cagaacctcc gtaccaacaa tggcattaat ggtggttgat ttccctgctt tcatggtacc
    10621 gacaattgca agcaccattt ccagtcggga aattttacgc aactcattat tcagcatcgc
    10681 gtgacgttcg gcgatattag gctgactcca gggtaaagcc agttgtggcg cgtcgtctcc
    10741 gggtacagag agaggcattt tttccagtaa ctgcaactgt tggcgagaaa gctgtaacag
    10801 gcgttcagcc tcctgactta actcatacag ggtctgtgtg tacatagaaa attcttcctt
    10861 aaagcaaatt ttgttatttt atttagccag at
//
LOCUS       DAPHKZ010000145        10863 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.145, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000145 DAPHKZ010000000
VERSION     DAPHKZ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10863
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.145"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            114..1256
                     /locus_tag="RH288_003964"
     CDS             114..1256
                     /locus_tag="RH288_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001327865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV4032970.1"
                     /translation="MECDLLMIKIEKVINKNDLKAFIAFPSSLYPDDPNWIPPLFIER
                     NEHLSAKNPGTDHIIWQAWVAKKAGQIVGRITAQIDTLHRERYGKDTGHFGMIDAIDD
                     PQVFAALFGAAEAWLKSQGASKISGPFSLNINQESGLLIEGFDTPPCAMMPHGKPWYA
                     AHIEQLGYHKGIDLLAWWMQRTDLTFSPALKKLMDQVRKKVTIRCINRQRFAEEMQIL
                     REIFNSGWQHNWGFVPFTEHEFATMGDQLKYLVPDDMIYIAEIDSAPCAFIVGLPNIN
                     EAIADLNGSLFPFGWAKLLWRLKVSGVRTARVPLMGVRDEYQFSRIGPVIALLLIEAL
                     RDPFARRKIDALEMSWILETNTGMNNMLERIGAEPYKRYRLYEKQI"
     gene            complement(1263..2027)
                     /gene="glcC"
                     /locus_tag="RH288_003965"
     CDS             complement(1263..2027)
                     /gene="glcC"
                     /locus_tag="RH288_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GlcC"
                     /protein_id="HDV4032971.1"
                     /translation="MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFS
                     RSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRA
                     LLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
                     SHNQVLVFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQ
                     RAARDHVRTVKKNLHDIELEGHHLIRSAVPLEMNLS"
     gene            2278..3777
                     /gene="glcD"
                     /locus_tag="RH288_003966"
     CDS             2278..3777
                     /gene="glcD"
                     /locus_tag="RH288_003966"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcD"
                     /protein_id="HDV4032972.1"
                     /translation="MSILYEERLDGALPDVDRTSVLMALREHVPGLEILHTDEEIIPY
                     ECDGLSAYRTRPLLVVLPKQMEQVTAILAVCHRLRVPVVTRGAGTGLSGGALPLEKGV
                     LLVMARFKEILDINPVGRRARVQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNV
                     AENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSPGFDLLALFTGSEGMLG
                     VTTEVTVKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAE
                     DFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFW
                     AGRKNAFPAVGRISPDYYCMDGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNM
                     HPLILFDANEPGEFARAEELGGKILELCVEVGGSISGEHGIGREKINQMCAQFNSDEI
                     TTFHAVKAAFDPDGLLNPGKNIPTLHRCAEFGAMHVHHGHLPFPELERF"
     gene            3777..4829
                     /gene="glcE"
                     /locus_tag="RH288_003967"
     CDS             3777..4829
                     /gene="glcE"
                     /locus_tag="RH288_003967"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcE"
                     /protein_id="HDV4032973.1"
                     /translation="MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQT
                     LDVRCHRGIVNYDPTELVITARAGTPLVAIEAALESAGQMLPCEPPHYGEEATWGGMV
                     ACGLAGPRRPWSGSVRDFVLGTRIITGAGKHLRFGGEVMKNVAGYDLSRLMAGSYGCL
                     GVLTEISMKVLPRPRASLSLRREISLQEAMNEIAQWQLQPLPISGLCYFDNALWIRLE
                     GGEGSVKAARELLGGEEVAGQFWQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEQ
                     LIDWGGALRWLKSTAEDNQIHRIARNAGGHATRFSAGDGGFAPLSAPLFRYHQQLKQQ
                     LDPCGVFNPGRMYAEL"
     gene            4840..6063
                     /gene="glcF"
                     /locus_tag="RH288_003968"
     CDS             4840..6063
                     /gene="glcF"
                     /locus_tag="RH288_003968"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcF"
                     /protein_id="HDV4032974.1"
                     /translation="MQTQLTEEMRQNARALEADSILRACVHCGFCTATCPTYQLLGDE
                     LDGPRGRIYLIKQVLEGNEVTLKTQEHLDRCLTCRNCETTCPSGVRYHNLLDIGRDIV
                     EQKVKRPLPERILREGLRQVVPRPAVFRALTQVGLVLRPFLPEQVSAKLPAETVKAKP
                     RPPLRHKRRVLMLEGCAQPTLSPNTNAATARVLDRLGISVMPANEAGCCGAVDYHLNA
                     QEKGLARARNNIDAWWPAIEAGAEAILQTASGCGAFVKEYGQMLKNDALYADKARQVS
                     ELAVDLVELLREEPLEKLAIRGDKKLAFHCPCTLQHAQKLNGEVEKVLLRLGFTLTDV
                     PDSHLCCGSAGTYALTHPDLARQLRDNKMNALESGKPEMIVTANIGCQTHLASAGRTS
                     VRHWIEIVEQALEKE"
     gene            6068..6472
                     /locus_tag="RH288_003969"
     CDS             6068..6472
                     /locus_tag="RH288_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein GlcG"
                     /protein_id="HDV4032975.1"
                     /translation="MKTKVILSQQMASAIIAAGQEEAQKNNWSVSIAVADDGGHLLAL
                     SRMDDCAPIAAYISQEKARTAALGRRETKGYEEMVNNGRTAFVTAPLLTSLEGGVPVV
                     VDGQIIGAVGVSGLTGAQDAQVAKAAAAVLAK"
     gene            6494..8665
                     /gene="glcB"
                     /locus_tag="RH288_003970"
     CDS             6494..8665
                     /gene="glcB"
                     /locus_tag="RH288_003970"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase G"
                     /protein_id="HDV4032976.1"
                     /translation="MSQTITQSRLRIDANFKRFVDEEVLPGTGLDAAAFWRNFDEIVH
                     DLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQPERVTVET
                     TGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDP
                     QRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVG
                     YRGDAAAPTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVA
                     AVDAEDKILLYRNLLGLMQGTLQEKMEKNGRQIVRKLNDDRHYTAADGSEISLHGRSL
                     LFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPK
                     MHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFIN
                     TGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGM
                     WAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQANIAQTEFN
                     AEFEPLLDDLLTIPVAENANWSAQEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIH
                     NVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNAGDPAYRPMAG
                     NFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH"
     gene            9020..10702
                     /gene="glcA"
                     /locus_tag="RH288_003971"
     CDS             9020..10702
                     /gene="glcA"
                     /locus_tag="RH288_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate permease GlcA"
                     /protein_id="HDV4032977.1"
                     /translation="MVTWTQMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGA
                     ITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVFLYKLTVASGQFDI
                     IRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLC
                     LIANTAPVAFGALGVPILVAGQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWK
                     GVKETWPAALVAGGSFAVTQFFTSNYIGPELPDITSALVSIVSLALFLKVWRPKNTET
                     AISMGQSAGAMVVNKPSSGGPVPSEYSLGQIIRAWSPFLILTVLVTIWTMKPFKALFA
                     PGGAFYSLVINFQIPHLHQQVLKAAPIVAQPTPMDAVFKFDPLSAGGTAIFIAAIISI
                     FILGVGIKKGIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMF
                     PFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMIS
                     PQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGIITLLQAYVFTGMLVS"
BASE COUNT         2522 a         2731 c         3053 g         2557 t
ORIGIN      
        1 taaatactat ttattcgtcg tttgtattca ttgggttgat tattaaggtg ccgttcgttg
       61 ctgttgcaac ctgtttgtca ccgttaatta tttgttaccc acagaacaga actatggaat
      121 gcgatctgct gatgattaaa attgaaaaag taattaataa aaatgacctt aaggcattta
      181 tcgcttttcc gtcatcactt tatcccgacg atccaaactg gataccccct ttattcattg
      241 aacgcaacga gcatttgtct gcgaaaaatc cggggacgga ccatatcatc tggcaggcgt
      301 gggtggcaaa aaaagcgggg cagatagttg ggcgtattac cgcgcaaata gataccttgc
      361 accgcgagcg ttacggcaaa gataccggtc atttcggcat gattgacgcc attgatgatc
      421 cgcaggtttt tgccgcgttg tttggcgcag cggaagcgtg gttgaagtca caaggtgcaa
      481 gtaagatcag cggtcctttc agcctgaata tcaatcagga aagcggatta ctgattgaag
      541 gttttgacac accaccctgt gcgatgatgc cacacggcaa accgtggtat gccgcgcata
      601 ttgaacaact gggttatcac aaaggcattg atttactggc gtggtggatg cagcgaaccg
      661 atctcacttt ctctccggcg ctaaaaaaac tgatggatca ggtgcgcaaa aaggtgacca
      721 ttcgctgcat caatcgtcag cggtttgccg aagagatgca gatcctgcgt gagattttca
      781 actctggctg gcagcacaac tggggatttg tgccgtttac cgaacatgaa ttcgcgacca
      841 tgggcgatca acttaaatat ctggtgccgg acgatatgat ctatatcgct gagattgatt
      901 ctgcaccctg cgcgtttatt gtcggcttgc cgaacatcaa cgaggcgatt gccgatctga
      961 acggatcgct ctttcccttc ggctgggcaa aattgctgtg gcgtttgaaa gtcagcggtg
     1021 tgcgaactgc gcgagtaccg ctgatgggcg tgcgcgacga gtatcagttc agccgcatcg
     1081 gcccggtgat tgcgctgtta ttgattgaag ccttacgcga tccgtttgcc cgccggaaga
     1141 tcgatgcgct ggagatgtca tggatcctcg aaaccaatac aggcatgaat aacatgctgg
     1201 aacgcattgg ggcggagccg tacaagcgtt accgattgta tgaaaagcaa atttaatacc
     1261 agctaactca ggttcatctc cagcggcacc gccgagcgaa tcaaatggtg gccttccagc
     1321 tcgatatcgt ggagattctt tttcacggtc cgcacatgat cgcgtgctgc gcgctgggcg
     1381 acgtgcggca gccgctgcaa caccgcgttg tagatccgcg catgctggcg atcgatctgc
     1441 tttttttgct gtggtcgatg gtagagatta tttacgctgg caaacactga attaaacatc
     1501 agatcggtca atgattgcag cgtaaacacc agcacctgat tgtgagaagc ctgacaaatg
     1561 gcgagatgga aagcgtgatc caactgcgca tgttcgatca gcgaaatctc tttgttattc
     1621 tcactggcgg cgagcatttt ttcataacag cgagttatca caacaaaatc agcctgcgtt
     1681 cccagcgttg ccgccagcct tgccgattcg ccctccagta atgcgcgaac gtcgagcaga
     1741 tcgtacagcg ttcgcggctg cgtgctgaac agatgaatta gcgggctggt gtcctgcacc
     1801 cgattaagcc gtgcgacacg agaatcgcga ccctgcgccg tttcaataat cccgcgcccg
     1861 cgcagcacgg tcagcccttc acgcagtgcg gagcgtgaga agccgagctt ttcacacagt
     1921 cgacgttccg agggaagcgg ctgaccgacc ttcagtacgc cgtcgataat taaccgttcg
     1981 atactctctg caaccacttc gcaaataggg cgacgttcat ctttcattcc cggacctcgt
     2041 gcacaggtag gaccaatttt tctgttctta actcgcaaaa cacgcacatc acgtaagtga
     2101 ttatgttata tcaatttaac attgagttaa ccaagacaag gtcacagagc tggaaaaaaa
     2161 atggtctgac cggtagctaa agagatagac gaaaacgaaa agcccgctta ataactgttc
     2221 acagaagcag cgcgcaaaaa tcagctgcca cacaacacaa caaagcgaag cctactcatg
     2281 agcatcttgt acgaagagcg tcttgatggc gctttacccg atgtcgaccg cacatcggta
     2341 ctgatggcac tgcgtgagca tgtccctgga cttgagatcc tgcataccga tgaggagatc
     2401 attccttacg agtgtgacgg gttgagcgcg tatcgcacgc gtccattact ggttgttctg
     2461 cctaagcaga tggaacaggt gacggcgatt ctggctgtct gccaccgcct gcgtgtgccg
     2521 gtggtgaccc gtggtgcagg caccgggctt tctggtggcg cgctgccgct ggaaaaaggt
     2581 gtgttgttgg tgatggcgcg ctttaaagag atcctcgaca ttaaccccgt tggtcgccgc
     2641 gcgcgcgtgc agccgggcgt gcgtaacctg gcgatctccc aggccgttgc gccgcataat
     2701 ctctattacg cgccggatcc ttcctcacaa atcgcctgct cgattggcgg caatgtggcg
     2761 gaaaatgccg gcggcgtcca ctgcctgaaa tatggtctga ccgtacataa cctgctgaaa
     2821 attgaagtgc aaacgctgga tggcgaggcg ctgacgctag gatcggatgc gctggattcg
     2881 cctggttttg acctgctggc gttgttcacc ggatcggaag gtatgctcgg cgtgaccacc
     2941 gaagtgacgg tgaagctgtt gccgaagccg cccgtggcgc gggttctgtt agcaagcttt
     3001 gactcggtag aaaaagccgg acttgcggtt ggtgacatca tcgctaatgg cattatcccc
     3061 ggcgggctgg agatgatgga taacctgtcg atccgcgcgg cggaagattt tattcatgcc
     3121 ggttatcccg tcgacgccga agcgattttg ttatgcgaac tggacggcgt ggagtctgac
     3181 gtacaggaag actgcgagcg ggttaacgac atcttgttga aagcgggtgc gactgacgtc
     3241 cgtctggcac aggacgaagc agagcgcgta cgtttctggg ccggtcgcaa aaatgcgttc
     3301 ccggcggtag gacgtatctc cccggattac tactgcatgg atggcaccat cccgcgtcgc
     3361 gcactgcctg gcgtactgga aggcattgcc cgtttatcgc agcaatatga tttacgcgtt
     3421 gccaacgtct ttcatgccgg agatggcaac atgcacccgt taatcctttt cgatgccaac
     3481 gaacccggtg aatttgcccg cgcggaagag ctgggtggga agatcctcga actctgcgtt
     3541 gaagttggcg gcagcatcag tggggaacat ggcatcgggc gagaaaaaat caatcaaatg
     3601 tgcgcccagt tcaacagcga tgaaatcacg accttccatg cggtcaaggc ggcgtttgac
     3661 cccgatggtt tgctgaaccc tgggaaaaac attcccacgc tacaccgctg tgctgaattt
     3721 ggtgccatgc atgtgcatca cggtcattta cctttccctg aactggagcg tttctgatgc
     3781 tacgcgagtg tgattacagc caggcgctgc tggagcaggt gaatcaggca attagcgata
     3841 aaacgccgct ggtgattcag ggcagcaata gcaaagcctt tttaggtcgc cctgtcaccg
     3901 ggcaaacgct ggatgtgcgt tgtcatcgcg gcattgttaa ttacgacccg accgagctgg
     3961 tgataaccgc gcgtgccgga acgccgctgg tggcgattga agcggcgctg gagagcgccg
     4021 ggcaaatgct cccctgtgag ccgccgcatt atggtgaaga agccacctgg ggcgggatgg
     4081 tcgcctgcgg gctggcgggg ccgcgtcgcc cgtggagcgg ttcggtccgc gattttgtcc
     4141 tcggcacgcg catcattacc ggcgctggaa aacatctgcg ttttggtggt gaagtgatga
     4201 aaaacgttgc cggatacgat ctctcacggt taatggccgg aagctacggt tgtcttggcg
     4261 tgctcactga aatctcgatg aaagtgttac cgcgaccgcg cgcctccctg agcctgcgtc
     4321 gggaaatcag cctgcaagaa gccatgaacg aaatcgccca gtggcaactc cagccgctac
     4381 ccattagtgg cttatgttac ttcgacaatg cgttgtggat ccgccttgag ggcggcgaag
     4441 gatcggtaaa agcggcgcgt gaactgctgg ggggcgaaga ggttgcgggt cagttctggc
     4501 agcaattgcg tgaacaacaa ctgccgttct tctcgttacc aggtacctta tggcgcattt
     4561 cattacccag cgatgcgccg atgatggatt tacccggcga gcaactgatc gactggggcg
     4621 gtgcgttacg ctggctgaaa tcgacagccg aggacaatca aatccatcgc atcgcccgca
     4681 acgctggcgg tcatgcgacc cgctttagtg ccggagatgg tggctttgcc ccgctatcgg
     4741 ctcctttatt ccgctatcac cagcagctta aacagcagct cgacccttgc ggcgtgttta
     4801 accccggtcg catgtacgcg gaactttgag gagcaggcta tgcaaaccca attaactgaa
     4861 gagatgcggc agaacgcgcg cgcgctggaa gccgacagca tcctgcgcgc ctgtgttcac
     4921 tgcggatttt gtaccgcaac ctgcccaacc tatcagcttc tgggcgatga actggacggg
     4981 ccgcgcgggc gcatctatct gattaaacag gtgctggaag gcaacgaagt cacgcttaaa
     5041 acacaggagc atctcgatcg ctgcctcact tgccgcaatt gtgaaaccac ctgtccttct
     5101 ggtgtgcgct atcacaattt gctggatatc gggcgtgata ttgtcgagca gaaagtgaaa
     5161 cgcccactgc cggagcgaat actgcgcgaa ggattgcgcc aggtagtgcc gcgtccggcg
     5221 gtcttccgtg cgctgacgca ggtagggctg gtgctgcgac cgtttttacc ggaacaggtc
     5281 agcgcaaaac tgcctgctga aacggtgaaa gctaaaccgc gtccgccgct gcgccataag
     5341 cgtcgggttt taatgttgga aggctgcgcc cagcctacgc tttcgcccaa caccaacgcg
     5401 gcaactgcgc gagtgctgga tcgtctgggg atcagcgtca tgccagctaa cgaagcaggc
     5461 tgttgtggcg cggtggacta tcatcttaat gcgcaggaga aagggctggc acgggcgcgc
     5521 aataatattg atgcctggtg gcccgcgatt gaagcaggtg ccgaggcaat tttgcaaacc
     5581 gccagcggct gcggcgcgtt tgtcaaagag tatgggcaga tgctgaaaaa cgatgcgtta
     5641 tatgccgata aagcgcgtca ggtcagtgaa ctggcggtcg atttagtcga acttctgcgc
     5701 gaggaaccgc tggaaaaact ggcaattcgc ggcgataaaa agctggcctt ccactgtccg
     5761 tgtaccctac aacatgcgca aaagctgaac ggcgaagtgg aaaaagtgtt gcttcgtctt
     5821 ggatttacct taacggacgt tcccgacagc catctgtgct gcggttcagc gggaacatat
     5881 gcgttaacgc atcccgatct ggcacgccag ctgcgggata acaaaatgaa tgcgctggaa
     5941 agcggcaaac cggaaatgat cgtcaccgcc aacattggtt gccagacgca tctggcgagc
     6001 gccggtcgta cctctgtgcg tcactggatt gaaattgtag aacaagccct tgaaaaggaa
     6061 taacaaaatg aaaactaaag tcattcttag ccagcaaatg gcgagtgcaa ttattgccgc
     6121 aggtcaggaa gaggcgcaga aaaataactg gtctgtttcc attgctgttg ccgatgacgg
     6181 cggtcatctg ctggcgttaa gtcgcatgga cgattgcgcg ccgattgcgg cttatatctc
     6241 ccaggagaaa gcgcgtaccg ccgcgctggg gcgtcgtgaa actaagggct atgaagagat
     6301 ggtgaacaac ggacgtaccg cgttcgtgac tgcgccgtta ttaacgtcgc tggaaggcgg
     6361 cgtaccggtt gttgtggatg ggcaaattat tggtgccgtg ggcgtttctg gtttaaccgg
     6421 agcacaggat gcgcaggtcg cgaaagcggc agcagcggtg ttggcgaaat aagcgaaaac
     6481 gaggagataa acaatgagtc aaaccataac ccagagccgt ttacgcattg acgccaattt
     6541 taaacgtttt gtggatgaag aagttttacc gggaacaggg ctggacgctg cggcgttctg
     6601 gcgcaatttt gatgagatcg ttcatgatct ggcaccagaa aatcgtcagt tgctggcaga
     6661 acgcgatcgc attcaggcag cgcttgatga gtggcatcgc agcaatccgg ggccggtaaa
     6721 agataaagcg gcctataaat ctttcctgcg tgaactgggc tacctggtgc cgcaaccgga
     6781 gcgcgtgacg gtggaaacca cgggcattga cagcgaaatc accagccagg cggggccgca
     6841 gctggtggtt ccggcaatga acgcccgcta cgcgctgaac gcggcgaacg ctcgctgggg
     6901 ctcactgtac gatgcgttat acggcagcga catcatcccg caggaagggg cgatggtcag
     6961 cggctacgat ccgcaacgcg gtgagcaggt tatcgcctgg gttcggcgtt tcctcgatga
     7021 atctctaccg ctggaaaacg gcagctatca ggatgtggtg gcgtttaagg tggttgataa
     7081 acaattacgc atccagttga aaaatggtaa agaaaccacg ttacgtactc cagcacagtt
     7141 tgtcggttac cgtggcgatg ccgctgcgcc gacctgcatt ttgctgaaaa ataacggcct
     7201 gcatattgag ctgcaaatcg atgccaatgg gcggattggc aaagacgatc cggcgcacat
     7261 caacgatgtt atcgtcgaag ctgctatcag taccattctc gactgcgaag attcggtcgc
     7321 ggcggttgat gcggaagata aaatcctgct gtaccgcaac ctgctgggcc tgatgcaggg
     7381 gactctgcaa gagaaaatgg agaaaaacgg tcggcaaatc gtgcgtaaac tgaatgacga
     7441 tcgtcattac accgccgccg atggctctga aatttctctg cacggacgct cgctgctgtt
     7501 tatccgcaac gtgggtcatt tgatgaccat tcctgtgatt tgggacagcg aaggcaatga
     7561 aatcccggaa ggcattcttg atggcgtcat gactggcgcg attgccctct atgatttaaa
     7621 agtgcagaaa aactcgcgca ctggcagcgt ctatattgtg aaaccgaaaa tgcacggtcc
     7681 gcaggaagtg gcgttcgcca acaaactgtt tacccgcatt gagacaatgc tcggtatggc
     7741 accgaatacc ctgaaaatgg gcattatgga tgaagaacgt cggacctcgc tgaacttgcg
     7801 tagctgtatc gctcaggcgc gcaaccgcgt ggcgttcatc aataccggtt tcctcgaccg
     7861 taccggcgat gaaatgcatt cggtgatgga agctggcccg atgctgcgta aaaatcagat
     7921 gaaatcgacg ccttggatca aagcctacga gcgtaataac gtgctttccg gtctgttctg
     7981 tgggctgcgc ggtaaagcgc aaattggtaa aggcatgtgg gcaatgccgg acctgatggc
     8041 agacatgtac agccagaagg gcgaccaact gcgtgccggg gcaaacacag cctgggttcc
     8101 gtcaccaacc gctgctacgc tccatgcgct gcactaccac caaaccaacg tacagagcgt
     8161 acaagccaac attgcccaga ccgagttcaa tgctgaattt gaaccgctgc tggacgatct
     8221 gctgactatt ccggttgctg aaaacgctaa ctggtcggcg caagagatcc aacaagagct
     8281 ggataacaac gtgcagggga ttctggggta cgtggtgcgc tgggtggagc aggggattgg
     8341 ttgttcaaaa gtgccggata ttcacaatgt ggcgttgatg gaagaccgcg caacgctgcg
     8401 tatctccagc cagcatatcg ccaactggtt acgtcacggt attctgacca aagaacaggt
     8461 gcaggcgtcg ctggagaata tggcgaaagt ggttgatcag caaaacgctg gcgatccggc
     8521 ttatcgtccg atggcgggga atttcgctaa ctcgtgtgct tttaaagctg ccagcgattt
     8581 aatcttcctc ggcgtgaaac agccaaacgg ttataccgaa ccgttattac acgcctggcg
     8641 tttacgcgaa aaagaaagtc attaatagcg tcaaaaaagc cccggcaagt tttattgtcg
     8701 gggctatgat agtaactgcg gtagtacatt tatcccggaa ataaccggag cgattatcag
     8761 ggtttaacaa tattaaatac ccgtagcgca ttactagcgg gcctaaaaca acaatatgga
     8821 catcttaacg atactctgcg cctgcgtgtg cggaacagaa acccttaccc gatatacttg
     8881 ttatgccaga ggtagcaatt gcgttagcgg cgtactgttg ctgtaaagta taacgcctat
     8941 attttacagt tcagtcctct tttgcttatt gcaaccttaa gtatatcaag catataaaga
     9001 taataagaga ctgaacaata tggttacctg gacccaaatg tatatgccga tgggaggact
     9061 ggggctatcc gctctggtcg ccctgatccc gataatattc ttcttcgttg cactcgcggt
     9121 attacgtctg aaaggacatg tcgctggagc aataaccctt atattatcta tcctgattgc
     9181 aatattcgcc tttaaaatgc cgattgatat ggcatttgct gctgcgggct atggctttat
     9241 ttatggatta tggccaatag cgtggattat tgtcgcggcg gtgttcctgt ataaattaac
     9301 cgttgccagc gggcagttcg atattatccg cagctcggtt atctccatca ccgacgatca
     9361 gcgtttgcag gtgttactga ttggtttctc ctttggtgcg ttgctggaag gagcggctgg
     9421 ctttggtgcg ccggtggcga ttaccggtgc gctgctggtg ggcctgggct tcaaaccgtt
     9481 atacgcggcg gggctgtgtc tgattgccaa tactgcgccg gtggcgtttg gtgcgttggg
     9541 cgtgccgatt ctggtcgccg gtcaggtaac gggaatcgat ccgttccaca ttggcgcaat
     9601 ggcgggacgt cagttaccgt tcctgtcggt tcttgtgccg ttctggctgg tagcaatgat
     9661 ggacggctgg aaaggggtga aagagacgtg gccagcggcg ctggttgctg ggggaagctt
     9721 cgctgtcact cagttcttta cctctaacta tattggtccg gaactgccgg atattacttc
     9781 ggcgctggtg agtatcgtct cactcgcttt attccttaaa gtctggcggc cgaaaaatac
     9841 cgaaacggca atcagcatgg gacaatccgc aggtgcgatg gtggtaaata agccatcttc
     9901 tggcggtccc gtgccttcag aatatagtct ggggcaaatc attcgagcgt ggtcaccgtt
     9961 tttaatctta acggtgctgg tcaccatctg gaccatgaag ccgtttaaag cgttatttgc
    10021 tccgggcggc gcgttttatt cactggtgat taatttccag atccctcatt tgcatcaaca
    10081 agtgttgaaa gcggcaccca ttgtcgccca accaacgcca atggatgcgg tgtttaaatt
    10141 cgaccccctc tcggctggcg gcaccgctat ttttattgcg gcgattatct ctatcttcat
    10201 cctcggtgtg gggatcaaga aaggtattgg cgtctttgcc gaaacgctaa ttagcttgaa
    10261 gtggccgata ctgtcgattg gcatggtgct ggcgttcgcc ttcgtcacca actattctgg
    10321 catgtccacc acgctggcgc tggtactggc aggtacaggc gtgatgttcc cgttcttctc
    10381 accgtttctc ggctggctgg gcgtattcct taccggctcg gacacctcct ctaacgccct
    10441 gtttggttca ctgcaatcga ccacggcgca gcaaatcaac gtctctgaca ccctgctggt
    10501 ggcagcaaac accagcggcg gcgtaactgg caagatgatc tccccgcaat ctatcgccgt
    10561 ggcctgcgcc gcgacgggca tggtgggccg agaatctgaa ctgttccgct acaccgtgaa
    10621 gcacagtctg atttttgcca gcgttatcgg cattatcacc ctgctgcagg cgtatgtgtt
    10681 taccgggatg ttagtctcgt aaatcaataa agccggatga tcgttaatat catccggctt
    10741 catttacatt attctgtctt attaattgaa aatcatttct cgctttatta tccatgcagc
    10801 aataatgttt tgcgttcaga taacctgcta aataattaag agcgtgagaa catctatttt
    10861 ttt
//
LOCUS       DAPHKZ010000146        10415 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.146, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000146 DAPHKZ010000000
VERSION     DAPHKZ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10415
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.146"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(284..2857)
                     /gene="clpB"
                     /locus_tag="RH288_003972"
     CDS             complement(284..2857)
                     /gene="clpB"
                     /locus_tag="RH288_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDV4032978.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQEL
                     HHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKEL
                     VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDE
                     ALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAV
                     Q"
     gene            complement(2987..3718)
                     /gene="pgeF"
                     /locus_tag="RH288_003973"
     CDS             complement(2987..3718)
                     /gene="pgeF"
                     /locus_tag="RH288_003973"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HDV4032979.1"
                     /translation="MSKLIVPQWPQPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNP
                     DHVEENRKRLFAAGNLPSKPVWLEQVHGKDVLKLTGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
                     AFEVGGEVREAFMAVDAKASAAFIQHGDKYLADIYQLARQRLANVGVEQIFGGDRCTY
                     TENETFFSYRRDKTTGRMASFIWLI"
     gene            complement(3715..4695)
                     /gene="rluD"
                     /locus_tag="RH288_003974"
     CDS             complement(3715..4695)
                     /gene="rluD"
                     /locus_tag="RH288_003974"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HDV4032980.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQR
                     VLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIIINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDR
                     QALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDWL"
     gene            4830..5567
                     /gene="bamD"
                     /locus_tag="RH288_003975"
     CDS             4830..5567
                     /gene="bamD"
                     /locus_tag="RH288_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HDV4032981.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTH
                     PNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLM
                     ENAYRQMQMNAQAEKVAKIIAANSSNT"
     gene            5838..6179
                     /gene="raiA"
                     /locus_tag="RH288_003976"
     CDS             5838..6179
                     /gene="raiA"
                     /locus_tag="RH288_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDV4032982.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVK
                     DANFVEEVEEE"
     misc_feature    6282..6407
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            6283..6330
                     /gene="pheL"
                     /locus_tag="RH288_003977"
     CDS             6283..6330
                     /gene="pheL"
                     /locus_tag="RH288_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phe operon leader peptide"
                     /protein_id="HDV4032983.1"
                     /translation="MKHIPFFFAFFFTFP"
     gene            6429..7589
                     /gene="pheA"
                     /locus_tag="RH288_003978"
     CDS             6429..7589
                     /gene="pheA"
                     /locus_tag="RH288_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HDV4032984.1"
                     /translation="MTSENPLLALREKISALDEKLLALLAERRELAVEVGKAKLLSHR
                     PVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
                     TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSK
                     FLNRYPHWKIEYTESTSAAMEKVAQAKSPHVAALGSEAGGTLYGLQVLERIEANQRQN
                     FTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRNHNLIMTRLESRPIH
                     GNPWEEMFYLDIQANLESAEMQKALKELGEITRSMKVLGCYPSENVVPVDPT"
     gene            complement(7632..8753)
                     /gene="tyrA"
                     /locus_tag="RH288_003979"
     CDS             complement(7632..8753)
                     /gene="tyrA"
                     /locus_tag="RH288_003979"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HDV4032985.1"
                     /translation="MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
                     KLPPLPKDCILVDLASVKNGPLQAMLVAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     KPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQG
                     DKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ"
     gene            complement(8764..9834)
                     /gene="aroF"
                     /locus_tag="RH288_003980"
     CDS             complement(8764..9834)
                     /gene="aroF"
                     /locus_tag="RH288_003980"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HDV4032986.1"
                     /translation="MQKDALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRKSI
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHQDLNGQLTARVA"
     gene            10044..10409
                     /locus_tag="RH288_003981"
     CDS             10044..10409
                     /locus_tag="RH288_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2799 domain-containing protein"
                     /protein_id="HDV4032987.1"
                     /translation="MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISG
                     SAIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQ
                     LHEVWQKGADENASTIRLN"
BASE COUNT         2650 a         2766 c         2444 g         2555 t
ORIGIN      
        1 ttctcagcgg cgcggggtgt gcataatacg ccttcccgct acagagtcaa gcatttcttt
       61 gcttttctct gttgagattc tcaggagaac cccgctgacc cggcggcgtg tttgccgttg
      121 ttccgtgtca gtggtggcgc attataggga gttattccgg cctgacaagc gaaaaatata
      181 aaaactttat cgttcgctca cttttcaggc aaaacatctt aaatatagtc ttttccgtct
      241 aacttataga caaaaacgag ccccgaaggg ctcgttttat catttactgg acggcgacaa
      301 tccggtcttc attaacttcc aggcgaatca ctttacccgg aaccaattca ccagacagta
      361 tttgctgtgc cagcgggttt tcgatctgct gctgaattgc acgtttcaga ggacgtgcac
      421 catagaccgg atcgtaaccg ttctcgctca gcagtttcag cgcctcgtca gaaatgtgga
      481 tttcataacc acgttcttcc agacgtttgt acagacgttt caactgaatc tgcgcaatcg
      541 aggcaatgtg ctgttcaccc agcggatgga agaccaccac ttcatcgata cggttaatga
      601 attccggacg gaagttatgg cttaccacac cgagcaccag ctctttcatg tgcgcataat
      661 ccagttcacc gaagcgttcc tgaatcagat cggaaccgag gttagaggtc ataatgacga
      721 ccgtattacg gaagtcgacc gttctccctt gcccgtcagt cagacgccca tcatccagta
      781 cctgcaacag aatgttgaag acatccggat gcgctttttc cacttcatcc agcaggatga
      841 cggaatacgg acgacgacgc accgcttcgg tcaggtagcc accttcttca taaccgacat
      901 atcccggagg cgcaccaacc aaacgagaca ccgagtgttt ctccataaac tcggacatat
      961 cgatacggac catcgcctcg tcgctatcaa acataaagtt cgccagcgcc ttacaaagct
     1021 ctgttttccc cacaccagtt gggccgagga acaggaatga accaatcggg cgatttggat
     1081 ccgccagccc cgcacggcta cgacgaatag cgttagatac cgcatcaacc gcttcgttct
     1141 gaccaattac gcgatggtgc agttcttgct ccatacgcag cagtttttcg cgctcgcttt
     1201 ccatcatgcg agaaaccgga atccccgtcc aacgcgccag cacttcagca atttcggcgt
     1261 cggtcacttt attacgcaac agacgcatag ttttgccttc gagctgcgtt gcggcttcca
     1321 gttgcttttc cagttccggg attttgccgt attgcagttc agacatccgc gccaggtccc
     1381 ccacacggcg agcctgttca atagcgattt tcgcctgttc cagttccgct ttaatggtct
     1441 gcgtaccaga aagcgatgcc ttctctgctt tccactcttc ttctaactcg gagtactgac
     1501 gttctttgtc gctcagttct tcgttgagca tatccagacg ttttttactg gcttcatcag
     1561 actctttcat taacgcctgt tgttccagtt tgagctggat gatacgacga tcgagtcggt
     1621 cgagttcttc tggttttgag tcaatctgca tacgaatgct ggatgctgct tcatcgatca
     1681 ggtcgatggc tttatccggc agctgacggt cagcaatgta gcgatgagac aacgtcgccg
     1741 ctgcaacaat tgccgggtca gtaatttgca catggtggtg caattcgtaa cgttctttca
     1801 ggccacgcag aatcgcaatg gtatcttcaa cagaaggctc ggcaacaaac actttctgga
     1861 aacgacgttc cagcgcagca tctttttcaa tgtactggcg atattcgtca agcgtcgtgg
     1921 cacctacgca gtgcaattca ccacgcgcca gcgccggttt cagcatgttt ccggcgtcca
     1981 ttgcgccatc ggctttaccc gcgccgacca tggtatgtaa ttcgtcgata aataggatga
     2041 cgttgccttc ctgtttggca agatcgttaa gcacgccttt taaacgttct tcaaactcac
     2101 cgcgatattt cgccccagcc accagcgcgc ccatatccag cgccagtacc cggcggcctt
     2161 tcaacccttc cggcacttcg ccgttgataa tacgctgcgc cagaccttca acgatggcag
     2221 ttttaccgac gccgggttca ccaatcagta ccgggttatt tttagtacga cgttgcagca
     2281 cctgaatggt acggcgaatt tcttcatcac gaccaatcac cggatcgagt ttgccctgtt
     2341 cggctcgttc ggtaaggtcg atggtatatt ttttcaaagc ctgacgttgg tcttcagcac
     2401 cttgatcgtt cacgctttca cctccacgca tttgttcaat cgcttgagta atgttggcgg
     2461 tggtcgcccc tgctgctttc aggatgtcgg ccagcgtgcc gcgagactca agtgccgcca
     2521 gaacgaacag ttctgacgag ataaagttat caccacgttt ttgcgccagc ttgtcgcaaa
     2581 gattaagaac gcgcaccaga tcctgtgatg gctggacatc accaccagta ccttcaacct
     2641 gcggtaaacg atttaatgcc tgattgatat ctgtgcgcaa ctggccagca tttatgccag
     2701 cggatgttaa taaaggacta accgaacccc cttcctgatt cagcagggcg ctcattaaat
     2761 gaagtggttc gataaattgg ttgtcgtgcc cgagtgcaag tgattgggca tcggcaagag
     2821 caagctggaa tttattagta agacgatcca gacgcataac tcctcccata acggatcaaa
     2881 gttgctactg gagattaaat gaggtcatcc ctcaattatt caaggttatt gaccagatta
     2941 atgtgaaaag aaaatcacgc gtaccggatc gtcttgattc tttaggttat atcagccaaa
     3001 tgaaacttgc catacgaccg gtggtcttgt cgcgacgata agagaagaaa gtctcatttt
     3061 ccgtatatgt acaacggtcg ccgccgaaaa tttgctcaac acccacgttc gccagacgct
     3121 gccgggcaag ctgataaata tccgccagat acttatcacc atgctgaatg aaagctgcac
     3181 ttgctttagc gtctactgcc ataaacgcct cgcgaacctc cccccccact tcgaacgcgc
     3241 gtggaccaat tgccggccct aaccaggcga gaatattttc cggattatca gcaaaacagg
     3301 aaaccgtctc ttccagcacg cctgcgcaca gtccacgcca gccagcatga gcggcggcga
     3361 cttccgttcc cgctcgattg caaaacagca cagggaggca gtcggcagtc atcactgcgc
     3421 aaaccgtgcc gggcgtattg ctataagagg catccgcccg ttttgaggca taaggttcgc
     3481 cagtgagctt aagcacatct ttgccgtgta cctgctcaag ccagaccggt ttagaaggca
     3541 aattgcccgc agcaaaaagt cgcttgcgat tctcctcaac gtgatccggg ttatcgccac
     3601 aatgggcacc gaggttgagt gagtcatacg ggggcaagct cacgccgccg atacgagtgg
     3661 agctacaggc cgcaacacct tttggctgcg gccactgcgg gacaatcagc ttactcataa
     3721 ccagtccact tcatccttat gttcttcgaa atcggcgcgc atcacctcaa tcagctccac
     3781 catatcttgt ggaataggcg catgccattc catttcgatg ccggagatcg ggtgataaag
     3841 acgcagcatg gttgcatgta gcgcctggcg gtcaaactta cgcagcgtgg agataaatgc
     3901 ttccgaagca ccttttggcg gacgcggacg gccaccataa accggatcgc ccaccagcgg
     3961 atgagtgata tgggccatat gcacgcggat ctggtgcgta cgtccagttt ccagacgcaa
     4021 ccgcagacgc gtgtgcacac ggaagtgttc catgatgcga tagtgagtca ccgctggttt
     4081 gcccatcgga tgcaccgcca tatgggtacg tttggtcggg tggcgactga ttggctcgtc
     4141 caccgtgcca cctgcggtca tatgaccaat cgccaccgct tcatactcac gagtaatttc
     4201 acgccgttgc aaagattcga ctaaacgcgt ctgagccgga acggtttttg ccacaaccat
     4261 caggccagtg gtgtctttat ccagacgatg gacgatgccc gcacgcggta catcggcaat
     4321 gggtggatag taatgaagca acgcattcag taccgtgcca tccgggttac ccgcgccagg
     4381 atgtaccacc aggtcgcgcg gtttattaat gataataatg tcttcatctt catagacgat
     4441 atccagcggg atatcctgcg gttcaaaacg cgcttcttct tcaatctcag cgttgatggc
     4501 aacctgctcg ccacccaata ctttttcttt cggcttatca caaactttgc cgttaaccag
     4561 cactcgctgg tcgaggatcc attcttttat tcgcgaacgt gaataatccg ggaacatttc
     4621 ggccaaagcc tgatctaagc gttgaccgag ttggttttcg gacaccgttg cagtgagctg
     4681 tactcgttgt gccatatata ctgcttcttc gtttatcgtt ggggttttac ggctttgccg
     4741 tttaatatag tgtgctattg tagctggtct taaccgggag caggaacaga gaatctcccg
     4801 tattacattt tgaggaaagt caaaacgtca tgacgcgcat gaaatatctg gtggcagccg
     4861 ccacactaag cctgtttttg gcgggttgct cggggtcaaa ggaagaagta cctgataatc
     4921 cgccaaatga aatttacgcg actgcacaac aaaagctgca ggacggtaac tggagacagg
     4981 caataacgca actggaagcg ttagataatc gctatccgtt tggtccgtat tcgcagcagg
     5041 tgcagctgga tctcatctac gcctactata aaaacgccga tttgccgtta gcacaggctg
     5101 ccatcgatcg ttttattcgc cttaacccga cccatccgaa tatcgattat gtcatgtaca
     5161 tgcgtggcct gaccaatatg gcgctggatg acagtgcgct gcaagggttc tttggcgtcg
     5221 atcgtagcga tcgcgatcct caacatgcac gagctgcgtt tagtgacttt tccaaactgg
     5281 tgcgcggcta tccgaacagt cagtacacca ccgatgccac caaacgtctg gtattcctga
     5341 aagatcgtct ggcgaaatat gaatactccg tggccgagta ctatacagaa cgtggcgcat
     5401 gggttgccgt cgttaaccgc gtagaaggca tgttgcgcga ctacccggat acccaggcta
     5461 cgcgtgatgc gctgccgctg atggaaaatg cataccgtca gatgcagatg aatgcgcaag
     5521 ctgaaaaagt agcgaaaatc atcgccgcaa acagcagcaa tacataacag aaacctgaaa
     5581 cacaaaacgg cagcccttga gctgccgttt ttttattctg tcagttgtga aactgaagcg
     5641 atttagtcgc tatcgatctc atcaaatatg gctcgctttg agatattcct caagtaaaaa
     5701 aacatctctt cctgcgattt ctcacaaaaa agattcgttg acaaaaagtg acaaaattat
     5761 gagattttca tcacacattt tgacatcagg aacggtatgc tgaattcacc aagacgggaa
     5821 gacaagaggt aaaatttatg acaatgaaca ttaccagcaa acaaatggaa attactccgg
     5881 ccatccgcca acatgtcgca gaccgtctcg ccaaactgga aaaatggcaa acacatctga
     5941 ttaatccaca tatcattctg tccaaagagc cacaagggtt tgttgctgac gccacaatca
     6001 atacacctaa cggcgttctg gttgccagtg gtaaacatga agatatgtac accgcaatta
     6061 acgaattgat caacaagctg gaacggcagc tcaataaact gcagcacaaa ggcgaagcac
     6121 gtcgtgccgc aacatcggtg aaagacgcca acttcgtcga agaagttgaa gaagagtagt
     6181 cctttatatt gagtgtatcg ccaacgcgcc ttcgggcgcg ttttttgttg acagcgtgaa
     6241 aacagtacgg gtactgtact aaagtcactt aaggaaacaa acatgaaaca cataccgttt
     6301 ttcttcgcat tcttttttac cttcccctga atgggaggcg tttcgtcgtg tgaaacagaa
     6361 tgcgaagacg aacaataagg cctcccaaat cggggggcct tttttattga taacaaaaag
     6421 gcaacactat gacatcggaa aacccgttac tggcgctgcg agagaaaatc agcgcgctgg
     6481 atgaaaaatt attagcgtta ctggcagaac ggcgcgaact ggccgtcgag gtgggaaaag
     6541 ccaaactgct ctcgcatcgc ccggtacgtg atattgatcg tgaacgcgat ttgctggaaa
     6601 gattaattac gctcggtaaa gcgcaccatc tggacgccca ttacattact cgcctgttcc
     6661 agctcatcat tgaagattcc gtattaactc agcaggcttt gctccaacaa catctcaata
     6721 aaattaatcc gcactcagca cgcatcgctt ttctcggccc caaaggttct tattcccatc
     6781 ttgcggcgcg ccagtatgct gcccgtcact ttgagcaatt cattgaaagt ggctgcgcca
     6841 aatttgccga tatttttaat caggtggaaa ccggccaggc cgactatgcc gtcgtaccga
     6901 ttgaaaatac cagctccggt gccataaacg acgtttacga tctgctgcaa cataccagct
     6961 tgtcgattgt tggcgagatg acgttaacta tcgaccattg tttgttggtc tccggcacta
     7021 ctgatttatc taccatcaat acggtctaca gccatccgca gccattccag caatgcagca
     7081 aattccttaa tcgttatccg cactggaaga ttgaatatac cgaaagtacg tctgcggcaa
     7141 tggaaaaggt tgcacaggca aaatcaccgc atgttgctgc gttgggaagc gaagctggcg
     7201 gcactttgta cggtttgcag gtactggagc gtattgaagc aaatcagcga caaaacttca
     7261 cccgatttgt ggtgttggcg cgtaaagcca ttaacgtgtc tgatcaggtt ccggcgaaaa
     7321 ccacgttgtt aatggcgacc gggcaacaag ccggtgcgct ggttgaagcg ttgctggtac
     7381 tgcgcaacca caatctgatt atgacccgtc tggaatcacg cccgattcac ggtaatccat
     7441 gggaagagat gttctatctg gatattcagg ccaatcttga atcagcggaa atgcaaaaag
     7501 cattgaaaga gttaggggaa atcacccgtt caatgaaggt attgggctgt tacccaagtg
     7561 agaacgtagt gcctgttgat ccaacctgat gaaaaggtgc cggatgatgt gaatcatccg
     7621 gcactggatt attactggcg attgtcattc gcctgacgca ataacacgcg gctttcactc
     7681 tgaaaacgct gtgcgtaatc gccgaaccag tgctccacct tgcggaaact gtcaataaac
     7741 gcctgcttat cgccctgctc cagcaactca atcgcctcgc cgaaacgctt atagtaacgt
     7801 ttgattaacg ccagattacg ctctgacgac ataatgatgt cggcataaag ctgcggatcc
     7861 tgagcaaaca gtcgcccgac catcgccagc tcaaggcggt aaatcggcga agagagcgcc
     7921 agaagttgct caagctgaac attttcttct gccaggtgca gcccgtaagc aaaagtagca
     7981 aagtggcgca gtgcctgaat aaacgccata ttctgatcgt gctcgacggc gctaatacga
     8041 tgcagccgag cgccccagac ctgaatttgc tccagaaacc attggtatgc ttccggttta
     8101 cgtccatcac accagaccac aacttgcttt gccaggctac cgctgtccgg accgaacatc
     8161 gggtgtagcc ccagcaccgg accatcatgc gccaccagca tggcctgtaa tggcccattt
     8221 ttcactgatg ccagatcgac cagaatacaa tctttcggta aaggcggtaa tttgccaata
     8281 acttgctcag taacgtggat tggcacacta acaatcacca ttccggcatc ggcaacaata
     8341 tcagccgctc gatcccagtc atgttgctcc agaatccgca cctgataacc cgagagggtc
     8401 agcatcttct cgaacaggcg tcccatctga ccgccaccgc cgacgataac caccggacgc
     8461 agtgacggac aaagtgtttt aaatcctttg tcgttttcac tggagtaaga ttcacgcatc
     8521 acccgacgca aaacatcctc aatcagatct ggcggtacac ccagagcttc cgcctctgca
     8581 cgacgcgagg ccaacataga tgcctcgcgc tccggaacat aaataggcag tccaaagcgg
     8641 cttttcacct cgcccacttc agcaaccagt tccagacgct tcgctaataa attcagcagc
     8701 gctttatcga cttcatcaat ttgatcgcgt aatgcggtca attcagcaac cataataaac
     8761 ctcttaagcc acgcgagccg tcagctgccc gttcagatcc tgatgaattt cacgcagcaa
     8821 ggcatcggtc atttcccagc taatgcaggc atcggttacg gatacaccgt atttcatttc
     8881 actgcgcggt tgctcggaag actgattgcc ctcgtggata ttactttcga tcatcagacc
     8941 aataattgag cgattgccat ctttgatttg agcaaccacg gattctgcca ccgcaggctg
     9001 acggcgataa tctttattgg aattaccgtg gctgcaatct accatcagag acgggcgcag
     9061 tcccgcctgt tccatctctt tttcacattg cgcaacatcc gcagggctat agttcggcgc
     9121 tttaccaccg cgcaggatca catggccgtc cggattcccc tgagtttgta gcaacgcaac
     9181 ctgccctgcc tggttaatgc caacaaaacg gtgcggctgg gcggcggcgc gcatagcgtt
     9241 aattgctgtt gccagactgc cgtcggtgcc gtttttaaaa ccaaccggca tggaaagccc
     9301 ggaggccatt tcacggtgag tttgcgattc cgttgtacga gcaccaattg ctgaccagct
     9361 aaacagatcg cccaggtatt gcgggctatt cggatctaac gcttccgtcg ccagtggcag
     9421 tcccatattc accagctcaa gcagcaattt acgcgcgatc tgcagcccgg cttctacatc
     9481 aaaagagcca tccatatggg gatcgttaat taaccctttc cagccgacag tggtacgggg
     9541 tttttcaaaa tagacgcgca ttaccagata gaggctatcg ctgacctctg cggcaagggc
     9601 tttaaatcga cgagcatatt ccagagcagt ttccggatca tgaatggaac aaggaccaca
     9661 tactaccagc agacgaggat cgcgcccggc gataatatct gaaatgcttt tacgcgagtc
     9721 agcaatctgg gcttcttgtt gcaggctcaa tggaaaagcg gccttcagtt gttccggagt
     9781 cattaaaacc tgttcgtcgg taatatgtac gttattcagc gcgtcttttt gcatgatggc
     9841 gatcctgttt atgctcgttt gcgatagttg atcctcagcg aggatgacgt aacgataaca
     9901 cataaagtaa agttttcaat ccatatttcg tacattttta tttacacagg caatttagtc
     9961 gcgctttcaa cccttacctc tgtatagata aatttacact ccctttgaaa acaatccgct
    10021 atgctttgaa aaaggagaaa gaaatgatga aaaagtttat cgcccccttg ttggctttac
    10081 tggttagcgg atgtcagatt gatccttata ctcacgcgcc aaccttgacc agcaccgact
    10141 ggtatgatgt cggtatggaa gatgcgatat cgggcagcgc cataaaagat gacgatgcat
    10201 ttagcgattc acaggcggat cgcggtctat accttaaagg atatgccgaa ggacaaaaga
    10261 aaacttgcca gaccgatttt acttatgccc gaggactttc cggtaaaagc tttcctgcca
    10321 gctgcaacaa tgttgaaaat gccagccaac tgcatgaagt atggcaaaaa ggggctgatg
    10381 aaaatgccag cacaatacga ttaaattaat taaaa
//
LOCUS       DAPHKZ010000147        10399 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.147, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000147 DAPHKZ010000000
VERSION     DAPHKZ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10399
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.147"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..664
                     /locus_tag="RH288_003982"
     CDS             <1..664
                     /locus_tag="RH288_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4032988.1"
                     /translation="KAELQIRSILQHAWAEIEHDIGYKSATGLPNEIRRYFSRLAGLL
                     EMADDEFIKIRKKISERQKEVAKELEQGTSDSVLDIFTLDEFLNTSRVMSELSEEIKE
                     KTGITVHGRYKDKDLGYLLNGLNLANITTIEQLNQKLSQMKKQIVDRIFCFGEPFINY
                     CRETTMPKEALLSYLCQIIVAFQNSPSLESEFNNKAGLNLKNSDISDFFSNIRENIST
                     QP"
     gene            complement(745..1197)
                     /locus_tag="RH288_003983"
     CDS             complement(745..1197)
                     /locus_tag="RH288_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HDV4032989.1"
                     /translation="MNEFKRFEDRLTGLIESLSPSGRRRLSAELAKRLRQSQQRRVMV
                     QKAPDGTPYAPRQQQSARKKTGRVKRKMFAKLITSRFLHIRASPEQASMEFYGGKSPK
                     IASVHQFGLSEETRKDGKKIDYPARPLLGFTGEDVQMIEEIILAHLER"
     gene            complement(1190..1657)
                     /locus_tag="RH288_003984"
     CDS             complement(1190..1657)
                     /locus_tag="RH288_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001406878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4032990.1"
                     /translation="MLKPDSLRRALTDAVTVLKTNPEMLRIFVDNGSIASTLATSLSF
                     EKRYTLNVIVTDFTGDFDLLIVPVLAWLRENQPDIMTTDEGQKKGFTFYADINNDSSF
                     DISISLMLTERTLVSEVDGALHVKNIPEPTPPEPVTRPMELYINGELVSKWDE"
     gene            complement(1620..1778)
                     /locus_tag="RH288_003985"
     CDS             complement(1620..1778)
                     /locus_tag="RH288_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein"
                     /protein_id="HDV4032991.1"
                     /translation="MPGSDPQTNGDLSADIRQLENALARCASQVKMIKHCQEENDAQT
                     RQPAQGAD"
     gene            complement(1765..2190)
                     /locus_tag="RH288_003986"
     CDS             complement(1765..2190)
                     /locus_tag="RH288_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001585210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HDV4032992.1"
                     /translation="MSKLMIVLVVLLSLAVAGLFLAKHKNASLRTSLDRANNVASGQQ
                     TTITMLKNQLHVALTRADKNELAQVALRQELENAAKREAQREKTITRLLNENEDFRRW
                     YGADLPDAVRRLHQRHACTDASDCPQRMPESEPLPDAGQ"
     gene            complement(2178..2603)
                     /locus_tag="RH288_003987"
     CDS             complement(2178..2603)
                     /locus_tag="RH288_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysA"
                     /protein_id="HDV4032993.1"
                     /translation="MKKLSLSRMLNVSLALMLALSLIYPQSVAVNFVAAWAILATVIC
                     VVAGGVGVYATEYVLERYGRELPPESLDVQIVTALFLQPVTWCRRAAGLVVMVATFIS
                     LVAAGWIFTALIYLVASLFFRLMQTACRQRLEGRELCQS"
     gene            complement(2618..3115)
                     /locus_tag="RH288_003988"
     CDS             complement(2618..3115)
                     /locus_tag="RH288_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 104 protein"
                     /protein_id="HDV4032994.1"
                     /translation="MPVINTHQNIAAFLDMLAVSEGTANHPLTKNRGYDVIVTGLDGK
                     PEIFTDYSDHPFAHGRPAKVFNRRGEKSTASGRYQQLYLFWPHYRKQLALPDFSPLSQ
                     DRLAIQLIHERGALDDIRAGRIERAISRCRNIWASLPGAGYGQREHSLEKLVTVWRTA
                     GGVPA"
     gene            complement(3115..3396)
                     /locus_tag="RH288_003989"
     CDS             complement(3115..3396)
                     /locus_tag="RH288_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDV4032995.1"
                     /translation="MTAEEKSVLSLFMIGVLIVVGKVLAGGEPITPRLFIGRMLLGGF
                     VSMVAGVVLVQFPDLSLPAVCGIGSMLGIAGYQVIEIAIQRRFKGRGKQ"
     gene            complement(3400..3603)
                     /locus_tag="RH288_003990"
     CDS             complement(3400..3603)
                     /locus_tag="RH288_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HDV4032996.1"
                     /translation="MKTFALQGDTLDAICVRYYGRTEGVVGAVLAANPGLAELGAVLP
                     HGTAVELPDVQTAPVAETVNLWE"
     gene            complement(3603..4112)
                     /locus_tag="RH288_003991"
     CDS             complement(3603..4112)
                     /locus_tag="RH288_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HDV4032997.1"
                     /translation="MMTLIIPRKEAPVSGEGTVVIPQPAGDEPVIKNTFFFPDIDPKR
                     VRERMRLEQTVAPARLREAIKSGMAETNAELYEYREQKIAAGFTRLADVPADDIDGES
                     IKVFYYERAVCAMATASLYERYRGVDASAKGDKKADSIDSTIDELWRDMRWAVARIQD
                     KPRCIVSQI"
     gene            complement(4212..4955)
                     /locus_tag="RH288_003992"
     CDS             complement(4212..4955)
                     /locus_tag="RH288_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HDV4032998.1"
                     /translation="MTSPAQRHMMRVSAAMTAQRDAAPLRHATVYEQMLVKLAADQRT
                     LKAIYSKELKAAKKRELLPFWLPWVNGVLEQGKGAQDDILMTVMLWRLDTGDIAGALE
                     IARYALKYGLTMPGKHRRTPPYMFTEEVALAAMRAHAAGESVDTRLLTETLELTATAD
                     MPDEVRAKLHKITGLFLRDGGDAAGALAHLQRATQLDCQAGVKKEIERLERELKPKPE
                     PQPKAATRAPRKTRSATPAKRGRPKKKAS"
     gene            complement(4959..6032)
                     /locus_tag="RH288_003993"
     CDS             complement(4959..6032)
                     /locus_tag="RH288_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HDV4032999.1"
                     /translation="MRQETRFKFNAYLSRVAELNGIDAGDVSKKFTVEPSVTQTLMNT
                     MQESSDFLTRINIVPVSEMKGEKIGIGVTGSIASTTDTAGGTERQPKDFSKLASNKYE
                     CDQINFDFYIRYKTLDLWARYQDFQLRVRNAIIKRQSLDLIMAGFNGVRRAETSDRSS
                     NPMLQDVAVGWLQKYRNEAPARVMSKVTDEEGHTTSEVIRVGKGGDYASLDALVMDAT
                     NNLIEPWYQEDPDLVVIVGRQLLADKYFPIVNKEQDNSEMLAADVIISQKRIGNLPAV
                     RVPYFPADAMLITKLENLSIYYMDDSHRRVIEENPKLDRVENYESMNIDYVVEDYAAG
                     CLVEKIKVGDFSTLAKATAEPGA"
     gene            complement(6091..6945)
                     /locus_tag="RH288_003994"
     CDS             complement(6091..6945)
                     /locus_tag="RH288_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HDV4033000.1"
                     /translation="MAKKVSKFFRIGVEGDTCDGRVISAQDIQEMAETFDPRVYGCRI
                     NLEHLRGILPDGIFKRYGDVTELKAEKIDDDSALKGKWALFAKITPTDDLIAMNKAAQ
                     KVYTSMEIQPNFANTGKCYLVGLAVTDDPASLGTEYLEFCRTAKHNPLNRFKLSPENL
                     ISVATPVELEFEDLPETVFTALTEKVKSIFGRKQASDDARLNDVHEAVTAVAEHVQEK
                     LSATEQRLAEMETAFSALKQDVADRADETSQAFTRLKNSLDHTESLTQQRRSKATGGG
                     GDALMTNC"
     gene            7119..8891
                     /locus_tag="RH288_003995"
     CDS             7119..8891
                     /locus_tag="RH288_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HDV4033001.1"
                     /translation="MTITTDTTLLHDPRRQAALLYWQGFSVPQIAAMLQMKRPTVQSW
                     KQRDGWDSVAPISRVEMSLEARLTQLIIKPQKTGGDFKEIDLLGRQIERLARVNRYSQ
                     TGNEADLNPNVANRNKGGRRKPKKNFFSDEAIEKLEQIFFEQSFDYQLHWYRAGLEHR
                     IRDILKSRQIGATFYFSREALLRALKTGHNQIFLSASKTQAYVFREYIIAFARLVDVD
                     LTGDPIVLGNNGAKLIFLGTNSNTAQSHNGDLYVDEIFWIPNFQVLRKVASGMASQSH
                     LRSTYFSTPSTLAHDAYPFWSGELFNRGRASAAERVEIDVSHNALAGGLLCADGQWRQ
                     IVTIEDALKGGCTLFDIEQLKRENSADDFKNLFMCEFVDDKASVFPFEELQRCMVDTL
                     EEWEDYAPFAANPFGSRPVWIGYDPSHRGDSAGCVVLAPPVVAGGKFRILERHQWKGM
                     DFATQAESIRKLTEKYNVEYIGIDATGLGVGVFQLVRSFYPAARDIRYTPEMKTAMVL
                     KAKDVIRRGCLEYDVSATDITSSFMAIRKTMTSSGRSATYEASRSEEASHADLAWATM
                     HALLNEPLTAGISTPLTSTILEFY"
     gene            8891..9925
                     /locus_tag="RH288_003996"
     CDS             8891..9925
                     /locus_tag="RH288_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001752368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV4033002.1"
                     /translation="MSKKKGKTLQPAAKKMTASAPKMEAFTFGEPVPVLDRRDILDYV
                     ECISNGRWYEPPISFTGLAKSLRAAVHHSSPIYVKRNILASTFIPHPWLSQQDFSRFV
                     LDFLVFGNAFLEKRYSTTGKVIRLETSPAKYTRRGVEEDVYWWVPSFHEPTPFAPGSV
                     FHLLEPDINQELYGLPEYLSALNSAWLNESATLFRRKYYENGAHAGYIMYVTDAVQDR
                     NDIEMLRENMVKSKGRNNFKNLFLYAPQGKADGIKIIPLSEVATKDDFFNIKKASAAD
                     LLDAHRIPFQLMGGKPENVGSLGDIEKVAKVFVRNELIPLQDRIREINGWLGQEVIRF
                     KNYSLDTDNG"
BASE COUNT         2363 a         2991 c         2716 g         2329 t
ORIGIN      
        1 caaagccgaa ttacaaatac gatcaatcct tcagcatgcc tgggcggaga ttgaacacga
       61 tattggttat aagtcggcca caggactgcc taatgaaata agaagatact tttcacgctt
      121 agctggtctt ttagaaatgg ccgatgatga atttattaaa atcagaaaaa agatttctga
      181 acggcagaaa gaggttgcaa aagaactaga gcaaggaact agtgattcag ttttagatat
      241 tttcactttg gatgaattct taaacacaag tcgagttatg agtgaacttt cagaagagat
      301 aaaagaaaaa acaggaatca cagtacatgg ccgatacaag gataaagatt tgggatacct
      361 actaaatggt ttaaacctag ccaacataac tacaatagaa caactcaatc aaaaactctc
      421 acaaatgaaa aagcagatcg tagatagaat attctgcttc ggagaaccat ttattaatta
      481 ttgcagagaa accaccatgc caaaagaagc tcttttgagt tatttatgtc aaattatcgt
      541 tgcgtttcaa aactcacctt cgttagaatc tgaatttaat aacaaagcag gtttaaatct
      601 gaaaaacagc gatatctccg attttttctc gaatataaga gaaaacataa gcacacaacc
      661 ttagctttag ttttaacgta ttctaacaga agactgctgc cggtaagcac cggcagcagc
      721 aatgaggtgt cgggaatgac acaactaacg ctcaaggtga gccaggataa tctcttcaat
      781 catctgcaca tcctcaccgg taaagccgag cagaggacgc gccggataat caattttctt
      841 accgtctttc cgggtttctt ccgacagacc gaactgatgc acactggcga ttttcggtga
      901 cttcccgccg taaaattcca ttgatgcctg ttccgggctg gcgcggatat gcaaaaaacg
      961 actggtgata agtttcgcaa acatttttcg cttaacgcga ccggtctttt ttctggcgct
     1021 ctgctgctgg cgtggcgcgt agggggtgcc gtccggggct ttctgtacca tcacccgacg
     1081 ctgctgactc tgccgcagac gtttcgccag ttcggcactc agtcgccgac gccctgacgg
     1141 tgacagcgat tcaatcagtc cggtcagccg gtcttcaaaa cgcttaaact cattcatccc
     1201 acttgctcac cagttcgcca ttgatataaa gctccatcgg gcgggtgacc ggctccggcg
     1261 gcgtgggttc cgggatattc ttcacatgca gcgcgccgtc cacctcactg accagcgtgc
     1321 gctcggtcag catcaggctg atgctgatat caaagctgct gtcattgttg atgtctgcat
     1381 aaaacgtgaa gccctttttc tggccttcgt cggtggtcat gatgtcgggc tgattttccc
     1441 gcagccacgc cagcaccggc acgatgagca ggtcaaaatc accggtaaag tcggtcacaa
     1501 tgacattgag cgtgtaacgc ttttcgaatg acagcgacgt cgccagtgtg gaggcaatac
     1561 tcccgttatc cacgaatatc cgcagcatct cggggttagt tttcagcacc gtgacggcat
     1621 cagtcagcgc cctgcgcagg ctgtcgggtt tgagcatcgt tttcttcctg acagtgttta
     1681 atcattttta cctggctggc acaacgtgcc agcgcgttct caagctgccg gatatcggca
     1741 cttaaatcgc cgttcgtctg cgggtcactg cccggcatcg ggcaaaggct cactttcggg
     1801 catgcgttgg ggacaatcac tggcgtcggt gcaggcgtgg cgctggtgca accggcgcac
     1861 agcatcaggc aggtcagcac cgtaccagcg gcgaaaatct tcgttctcat tcagtaacct
     1921 cgtgatggtt ttctcgcgct gtgcttcacg tttcgcggcg ttctccagtt cctgacgcag
     1981 tgccacctgc gccagctcgt ttttatctgc cctggtgagc gcaacatgaa gctgattttt
     2041 cagcatggtg atggtcgtct gctgaccgct ggctacgttg ttcgccctgt ccagcgaggt
     2101 gcgcaggctg gcgtttttat gcttcgccag aaacagaccc gccaccgcca gcgataacaa
     2161 cacaaccagc acaatcatca gctttgacat agttcccgcc cctcaagacg ctgacggcag
     2221 gcagtctgca tcagccggaa aaacagcgat gccacgagat aaatcagcgc ggtaaaaatc
     2281 cacccggcag cgaccagcga gataaacgtc gccaccatca ccaccagacc cgccgcccgt
     2341 ctgcaccacg tcaccggctg caaaaacagc gccgtgacaa tctgcacatc cagagattct
     2401 ggcggcagct cgcgcccgta gcgttccagc acatactcag tggcatacac gccgacacca
     2461 ccggcaacca cacagataac cgtcgccaga atcgcccagg cggcgacaaa attgacggcc
     2521 acgctctgcg ggtaaatcag ggacagtgcc agcatcagcg ccagcgacac gttcagcatc
     2581 cgtgaaaggg ataatttttt catggtgttt actccgttta agccggtacg ccgccagcgg
     2641 tacgccagac ggtgaccagt ttttccagtg aatgctcacg ctgaccgtaa ccggcccccg
     2701 gcagggacgc ccagatattg cgacagcgtg aaatggcgcg ctcaatgcgc cccgcccgga
     2761 tgtcatccag cgcaccgcgt tcgtggatca actgaatggc gagtctgtcc tgcgacaacg
     2821 gactgaaatc cggcagggca agctgtttgc ggtaatgcgg ccagaacagg taaagttgct
     2881 gatagcgacc ggaggccgtg gatttttcac cgcgacggtt aaacaccttc gccggtcggc
     2941 catgcgcgaa cgggtggtca ctgtagtcgg tgaaaatttc cggcttcccg tccagtccgg
     3001 tgactatcac gtcatagccc cggtttttcg tcagcggatg attcgccgtc ccttcggaca
     3061 ctgccagcat gtcgagaaag gccgcgatat tctgatgcgt gttaattacc ggcattactg
     3121 tttccccctg cccttaaaac ggcgctgaat ggcaatctca atcacctgat aaccggcgat
     3181 acccagcatg gagccgatac cgcacaccgc aggcagtgac aggtcaggaa actgcaccag
     3241 aacaacaccg gcaaccatcg agacaaaacc accgagcaac atgcgcccga taaacagacg
     3301 cggggtgatg ggttcaccac cggcaagcac tttgccgaca acaatcagca ccccaatcat
     3361 gaaaagcgac aggacgcttt tttcttctgc tgtcatgcgt tactcccaca gattgacagt
     3421 ttcagccacg ggcgcggtct gaacgtcggg cagttcgacg gcggtgccat gtggcagcac
     3481 cgcccccagt tcagccagtc ccggatttgc ggcgagcacg gccccgacca cgccctcagt
     3541 gcgcccgtaa taccggacac aaatggcgtc gagcgtgtcg ccctgtagcg caaaggtctt
     3601 catcagattt gactcacgat gcagcgcggc ttgtcctgga tgcgcgccac tgcccagcgc
     3661 atatcccgcc acagctcatc aatggtgctg tcaatgctgt cggccttctt gtcgcctttc
     3721 gcactggcat ccacgccgcg ataacgctca taaagcgacg cggtcgccat cgcacacacg
     3781 gcgcgctcgt agtaaaaaac tttgatgctt tcaccgtcga tatcgtctgc cggaacgtcc
     3841 gccagacgcg taaaaccggc ggcaattttc tgttcgcggt actcgtacag ctccgcattt
     3901 gtttccgcca tgcctgactt gatggcctca cgcagacggg cgggggcgac ggtctgctca
     3961 aggcgcatac gttcccggac gcgcttcggg tcgatatcgg gaaaaaagaa cgtgttttta
     4021 atcaccggct cgtcgcctgc cggttgcggg atgaccaccg taccctcacc ggatacagga
     4081 gcctcctttc gcggaataat cagcgtcatc atgactacct ctgaaaagtc gggcggtgga
     4141 cgccggtgca gtgtcaggtg attcaccctc actgaccggc gtgccgccct ggcgcggggc
     4201 gcattcggtt gttaactggc tttctttttc gggcgtccac gttttgccgg tgtcgcactc
     4261 cgggtcttac gcggggcgcg ggtggccgct tttggctgcg gctccggctt cggtttcagc
     4321 tcccgctcca gtcgttcaat ctcttttttg acgcctgcct gacagtcgag ctgtgtcgca
     4381 cgttgcaggt gagccagcgc accggcggca tcaccaccgt cacgcagaaa cagaccggtg
     4441 attttgtgca gctttgcgcg cacttcatca ggcatgtctg ccgtggcggt cagttcaagg
     4501 gtttccgtca gcaggcgggt atccacagac tcaccggcag cgtgagcacg catggccgcg
     4561 agcgccacct cctcggtgaa catgtacggc ggggtgcggc ggtgtttacc cggcatggtc
     4621 agaccgtact tcagggcata acgggcaatc tccagcgcac cggcaatatc gccggtatcc
     4681 agacgccaca gcatgaccgt catcagaatg tcatcctgtg cacctttgcc ctgctccagc
     4741 acgccgttca cccacggcaa ccagaacggc agcagttcgc gttttttcgc ggccttcagc
     4801 tcttttgaat aaatcgcttt cagtgtgcgc tggtctgcgg cgagcttaac cagcatctgc
     4861 tcatagacag ttgcatgtcg cagcggggcg gcgtcccgct gcgcggtcat cgctgccgag
     4921 acccgcatca tgtggcgctg tgcgggactc gtcatcggtt acgctcccgg ctctgcggtc
     4981 gctttagcca gtgtggagaa atcaccgacc ttaatttttt ccaccagaca accggcggcg
     5041 tagtcttcca ccacgtaatc aatgttcatt gactcgtagt tctccacgcg gtcgagtttc
     5101 gggttttcct caatcacgcg gcgatggctg tcatccatgt agtagatgga caggttttcc
     5161 agctttgtga tgagcatcgc atccgccggg aagtacggga cgcgtaccgc cggcaggtta
     5221 ccgatgcgtt tctggctgat gatgacgtca gcggccagca tttcgctgtt gtcctgctcc
     5281 ttgttgacga tgggaaaata cttgtccgcc agtagctgac gtcccacaat caccacaagg
     5341 tcagggtctt cctgatacca cggctcaatc aggttgttgg tcgcatccat caccagtgcg
     5401 tcaaggctgg cataatcacc gcccttaccc acgcggataa cctcagaggt ggtgtgccct
     5461 tcctcgtcag tgaccttgct catcacgcgc gccggggctt cattgcggta tttctgcagc
     5521 cagccgaccg ccacatcctg cagcatcgga ttgctgctgc ggtcagaggt ttcggcacgc
     5581 ctcacgccgt taaaaccggc catgattaaa tcaagggact ggcgtttgat aatggcgtta
     5641 cggacacgga gctggaaatc ctgataacgc gcccacaggt ccagcgtttt gtagcggata
     5701 taaaaatcga agttaatctg gtcgcattcg tacttgtttg acgccagctt cgagaagtcc
     5761 ttcggctgac gctcggtgcc accggcggtg tcggtggtgc tggcgatgga gccggtgaca
     5821 ccgataccaa ttttttcccc tttcatttcg ctgaccggca caatgttgat gcgggtcaga
     5881 aagtcagagg actcctgcat ggtgttcatc agggtctggg tgaccgacgg ttcaacggtg
     5941 aattttttcg acacatcacc ggcgtcgatg ccgttcagct cggcaacacg ggacaggtag
     6001 gcattaaatt taaagcgggt ttcctggcgc atagtttttc ctgaaattaa gggttaatcg
     6061 tggaggtttt cccggactga ctgacgccgg tcagcagttc gtcatcaggg cgtcaccgcc
     6121 accgccggtg gccttgctgc ggcgctgctg ggtcagactt tcggtgtggt cgagactgtt
     6181 tttcaggcgg gtgaatgcct ggctggtttc atccgccctg tcagctacat cctgcttaag
     6241 tgcggaaaag gcggtttcca tctctgcgag gcgctgctca gtggcgctca gtttttcctg
     6301 cacatgttca gcaacagcgg tcaccgcttc atgcacatca ttcagacggg cgtcatcgct
     6361 ggcctgtttg cggccaaaaa tggatttcac cttttcggtc agggcggtga acacggtttc
     6421 aggcaggtct tcaaattcca gctcaacagg cgttgccact gaaatcagat tttcagggct
     6481 taatttgaag cggttcaggg ggttgtgttt tgccgtgcgg cagaattcca ggtattccgt
     6541 gccgaggctt gccggatcat cggtgacggc cagccccacc agataacatt tgccggtgtt
     6601 ggcaaagttc ggctgaattt ccattgaggt gtagaccttc tgcgcggcct tgttcatcgc
     6661 gataaggtca tcggtcgggg tgattttcgc aaacagcgcc catttgcctt tcagcgccga
     6721 atcatcgtca atcttttcgg ccttcagttc ggtcacatcg ccataacgct taaaaatacc
     6781 gtcaggcagg atgccgcgca gatgttccag gttaatgcgg caaccataga cacgcgggtc
     6841 aaaggtttcg gccatttcct gaatatcctg cgcactgatg acacgcccgt cacaggtgtc
     6901 accctcaacg ccgatacgaa agaattttga gacttttttt gccattgtca ggagtcctga
     6961 atagtgatta gaggagtcac atgtcggcat cagtttcccg acgatgcgca tcctccgcca
     7021 tcagtcccgg atggcttatc actgacacaa cagcacctta gcgaatcgcg gggcgcgact
     7081 cagtagcctt gccgtgtatt catcacggcg aggtattcat gaccatcacc acagacacca
     7141 ctcttttaca cgacccgcgt cgtcaggcgg cgctgctgta ctggcagggg ttttccgtgc
     7201 cgcagattgc cgccatgttg cagatgaaac gcccgacggt gcagagctgg aaacagcgcg
     7261 acggctggga cagcgttgcc cccatcagcc gtgtcgaaat gagtctggaa gcgcggctga
     7321 cccagctcat catcaaaccg cagaaaaccg gcggtgactt caaggaaatt gacctgctgg
     7381 gacgccagat tgaacggctg gcgcgggtca accgctacag tcagaccggc aacgaggcag
     7441 accttaatcc gaacgtcgct aaccgcaaca aaggcgggcg tcgcaaaccg aaaaagaatt
     7501 ttttcagtga cgaggccatc gaaaagctgg agcagatttt ctttgagcag tctttcgact
     7561 atcagttgca ctggtatcgc gccgggcttg agcaccgcat ccgcgatatc ctgaaatccc
     7621 gccagattgg cgcgacgttt tatttttccc gcgaggcgct gctgcgcgcc ctgaaaaccg
     7681 gtcataacca gatttttctg tcggccagta aaacgcaggc gtatgtgttc cgcgaataca
     7741 tcatcgcctt tgcccggctg gttgacgttg acctgaccgg tgacccgatt gtcctgggca
     7801 ataacggcgc aaaactgatt tttctcggca ccaactccaa caccgcgcag agccataacg
     7861 gcgacctgta cgtcgatgag attttctgga tcccgaattt tcaggtactg cgtaaggtgg
     7921 catcaggtat ggcctcacag agtcacctgc gctcgaccta tttctccacc ccgtccacgc
     7981 tggcgcacga cgcctatccg ttctggtcgg gtgaactgtt caaccgggga cgcgccagcg
     8041 ccgccgaacg cgtggaaatc gacgtcagtc ataacgccct tgccggtggg cttctctgtg
     8101 cggacggcca gtggcggcag attgtcacca ttgaggacgc cctgaaaggt ggctgcacgc
     8161 tgttcgacat tgagcagctc aaacgtgaaa acagcgccga cgattttaaa aacctgttca
     8221 tgtgtgaatt tgttgacgac aaggcgtcgg tgttcccgtt cgaggagctg caacgctgca
     8281 tggtcgacac gctggaagaa tgggaagact atgcgccgtt tgccgccaat ccgttcggct
     8341 cccgcccggt ctggattggt tacgacccgt cacaccgtgg cgacagtgcc ggatgcgtgg
     8401 tgctggcacc gccggtggtg gccggtggca aattcagaat acttgagcgt caccagtgga
     8461 aaggcatgga ctttgccaca caggcggaat ccatccgcaa actcaccgaa aaatacaacg
     8521 tcgaatacat cggaattgat gccaccggcc tcggtgtcgg cgtgttccag ctcgtgcgct
     8581 cgttctatcc cgccgcgcgc gatatccgct acacgccgga aatgaaaacc gcaatggtgc
     8641 tcaaggcaaa agacgtcatc cgccgtggct gtctggaata tgacgtcagc gccaccgaca
     8701 tcaccagctc gtttatggct atccgcaaga ccatgaccag cagcggacgc agcgccactt
     8761 atgaggccag ccgcagcgag gaagccagcc acgccgacct cgcctgggcg accatgcacg
     8821 ccctgttaaa tgagccactc accgccggta tcagcacacc gctgacatcc accattctgg
     8881 agttttactg atgagcaaga aaaaagggaa aacactgcaa cctgcggcaa aaaaaatgac
     8941 cgccagcgcc ccgaaaatgg aggcattcac ctttggcgaa ccggtgccgg tactcgaccg
     9001 ccgtgacatt ctggattacg tcgagtgcat cagtaacggc agatggtatg agccaccaat
     9061 cagctttacc ggtctggcaa aaagcctgcg tgctgccgtg catcacagct caccgattta
     9121 cgtcaaacgt aatattctgg cctcgacatt tatcccgcat ccgtggcttt cccagcagga
     9181 tttcagccgc tttgtgctgg attttctggt gttcggtaat gcgtttctgg aaaagcgtta
     9241 cagcaccacc ggtaaggtca tcagactgga aacctcaccg gcaaaatata cccgccgtgg
     9301 cgtggaagag gatgtttact ggtgggtgcc gtccttccat gagccgacac ctttcgcgcc
     9361 cggctccgtg tttcacctgc tggagccgga tattaatcag gagctgtacg gcctgccgga
     9421 atatctcagc gcccttaact ctgcctggct gaatgagtcg gccacgctgt tccgccgcaa
     9481 gtattacgaa aacggcgcac atgccggata catcatgtac gtcaccgatg ccgtgcagga
     9541 tcgcaacgat atcgaaatgc tccgcgaaaa catggtgaag tcgaaaggcc gcaacaactt
     9601 taaaaatctg tttctctatg ccccgcaagg gaaagccgac ggcattaaaa ttatcccgct
     9661 cagtgaagtg gcgacgaagg acgatttttt taatatcaaa aaagccagcg ccgctgacct
     9721 gctggacgca caccgcatcc cctttcagtt gatgggcggc aagccggaga acgtcgggtc
     9781 actgggagat attgagaaag tggcaaaggt ctttgtccgc aatgagctta tcccgttaca
     9841 ggacaggatc cgcgagataa acggctggct cggtcaggag gtcatccgct ttaaaaacta
     9901 ctcactggac actgacaacg gctgaacatc gccgcctgcg ggcggctttt ttacaacccg
     9961 ccatcacgcc ctcacacgct caccaccgca caaaacagcc cgcatacaca ccaacgcccc
    10021 ggcgaacaat ctaaacgcca tcacgacgcg ctcagacgct gaaaaaataa aatcagcacc
    10081 accgccagcg cgcagtgctt tccccgcctc gcccgcccgc ttcatgagac ggttttaatg
    10141 cagttgcatt atgtcccgct cctcagtgct gcgctccatc ctgattacaa aaaccgttat
    10201 caaaaacaca tgcaaataga cgcagtcaaa tgcgctaccg cctctcgcaa taccttcaat
    10261 ttcatgataa aaaacatcat ccctaacaag agcattatcc tcatgaaaaa agtatatgaa
    10321 ctaaccagtg aagaagcact gtcatatttt cttcgccatg actcctacac aaccttagaa
    10381 ttaccggctt atattaatt
//
LOCUS       DAPHKZ010000148        10262 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.148, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000148 DAPHKZ010000000
VERSION     DAPHKZ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10262
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.148"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            57..632
                     /gene="ssuE"
                     /locus_tag="RH288_003997"
     CDS             57..632
                     /gene="ssuE"
                     /locus_tag="RH288_003997"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HDV4033003.1"
                     /translation="MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAP
                     EDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVV
                     LPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTR
                     LDTALETFWQALHRRDVQVPDLLSLRGNAHA"
     gene            625..1584
                     /gene="ssuA"
                     /locus_tag="RH288_003998"
     CDS             625..1584
                     /gene="ssuA"
                     /locus_tag="RH288_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415456.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein SsuA"
                     /protein_id="HDV4033004.1"
                     /translation="MRNIIKLALAGLLSVSTFAVAAESSPEALRIGYQKGSIGMVLAK
                     SHQLLEKRYPESKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVG
                     VEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
                     TYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPY
                     AEKNGAFIQGVLATFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKP
                     VNAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL"
     gene            1581..2726
                     /gene="ssuD"
                     /locus_tag="RH288_003999"
     CDS             1581..2726
                     /gene="ssuD"
                     /locus_tag="RH288_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="HDV4033005.1"
                     /translation="MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGY
                     TGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGR
                     ALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLQRETVDFNGKHIHVRGA
                     KLLFPAIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAH
                     GRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAAL
                     HNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPH
                     LEEAYRVGELLFPLLDVAIPEIPQPQPLNPQGEAVANDFIPRKVAQS"
     gene            2737..3528
                     /gene="ssuC"
                     /locus_tag="RH288_004000"
     CDS             2737..3528
                     /gene="ssuC"
                     /locus_tag="RH288_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415454.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter permease
                     SsuC"
                     /protein_id="HDV4033006.1"
                     /translation="MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEG
                     VVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQ
                     MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARS
                     YGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREF
                     LQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV"
     gene            3525..4292
                     /gene="ssuB"
                     /locus_tag="RH288_004001"
     CDS             3525..4292
                     /gene="ssuB"
                     /locus_tag="RH288_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonates ABC transporter ATP-binding
                     protein"
                     /protein_id="HDV4033007.1"
                     /translation="MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVG
                     RSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVG
                     LGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
                     GALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD
                     IPRPRRLGSVRLAELEAEVLQRVMQRGESETRLRKQG"
     gene            complement(4335..6947)
                     /gene="pepN"
                     /locus_tag="RH288_004002"
     CDS             complement(4335..6947)
                     /gene="pepN"
                     /locus_tag="RH288_004002"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HDV4033008.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVR
                     HGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTV
                     KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNS
                     VLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNE
                     MAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRN
                     ACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWH
                     QNGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFH
                     AEDGSGYLFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            7213..8415
                     /gene="pncB"
                     /locus_tag="RH288_004003"
     CDS             7213..8415
                     /gene="pncB"
                     /locus_tag="RH288_004003"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDV4033009.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGD
                     DLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSN
                     DNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSAL
                     TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQ
                     AHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASR
                     YQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPHIKKAS"
     gene            8584..9984
                     /gene="asnS"
                     /locus_tag="RH288_004004"
     CDS             8584..9984
                     /gene="asnS"
                     /locus_tag="RH288_004004"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDV4033010.1"
                     /translation="MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGW
                     VEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNASF"
BASE COUNT         2315 a         2632 c         2772 g         2543 t
ORIGIN      
        1 gaccgaattg ttatcaatgt taacaaaaaa agaacaattg gttataagga gagagtatgc
       61 gtgtcatcac cctggcgggt agtcctcgct ttccttctcg ctccagctcc ttgctggaat
      121 atgcgcggga aaaactaaat ggcctggatg tagaggttta tcactggaat ctgcaaaact
      181 tcgccccgga agatctactt tatgctcgtt tcgatagtcc ggcactcaag accttcaccg
      241 aacagctgca acaggccgat gggctgattg tcgccacgcc tgtgtataaa gccgcctatt
      301 ccggtgcgtt gaaaaccctg ctcgacctgc tgccagaacg cgctttgcaa ggcaaagtgg
      361 tgctaccgct ggcgacgggc ggtaccgtgg cccatctgct ggcggtcgat tatgccctta
      421 aaccagtttt aagcgcactg aaagctcagg agatcctgca cggcgtgttt gccgatgact
      481 cacaagtaat tgattaccat cacagacccc agttcacgcc aaatctgcaa acccgtcttg
      541 ataccgcgct agaaactttc tggcaggcat tgcaccgccg cgatgttcag gttcctgacc
      601 ttctgtctct gcgaggtaat gcccatgcgt aacatcatta aactggcgct ggcgggattg
      661 cttagcgtct ctacttttgc ggttgctgca gaatcctcgc ctgaagcgtt acgtataggc
      721 tatcagaaag gcagtattgg tatggtgctg gcaaaaagcc accagttact ggaaaaacgc
      781 tatccggaat caaaaatctc ctgggtggag ttccccgcgg gtccgcaaat gttggaagcg
      841 ttaaacgttg gcagtattga tctcggcagt accggggata ttccgccaat ctttgcccag
      901 gctgccgggg ctgatttggt gtacgtgggc gtcgagccac cgaagcccaa agccgaagtg
      961 attctggtgg cagaaaacag cccgatcaaa accgtagccg atcttaaagg tcacaaagtt
     1021 gcctttcaga aaggttccag ttcacacaac cttttactgc gtgcactgcg tcaggccgga
     1081 cttaagttta ccgatatcca acccacttac ctgacgcccg ctgatgcccg cgccgcgttc
     1141 cagcaaggta acgttgacgc ctgggctatc tgggatccct actactctgc tgcattatta
     1201 cagggcggcg tgcgggtgct gaaagacggc accgatctca atcaaactgg atcgttttat
     1261 ctggcagctc gtccctatgc agaaaaaaac ggcgctttta ttcagggcgt actggcaacc
     1321 tttagtgagg ccgatgcgtt aacccgcagc cagcgcgagc aaagcatcgc tttactggca
     1381 aaaacgatgg gcttaccggc accggtgatt gcctcttact tagatcatcg ccctcctacc
     1441 accatcaaac cggttaacgc cgaggttgcc gccttacagc agcaaacggc agatctgttt
     1501 tatgaaaatc gtctggtgcc gaaaaaagtc gatattcgcc agcgcatctg gcagcccact
     1561 caactggaag gaaaacaatt atgagtctga atatgttctg gtttttaccg acccacggtg
     1621 acgggcatta tctgggaacg gaagaaggtt cacgcccggt tgatcacggt tatctgcaac
     1681 aaattgcgca agcggcggat cgtcttggct ataccggtgt gctaattcca acggggcgct
     1741 cctgcgaaga tgcgtggctg gttgccgcat cgatgatccc ggtgacgcag cggctgaagt
     1801 ttcttgtcgc cctgcgtccc agcgtaacct cacctaccgt tgccgcccgc caggccgcca
     1861 cgcttgaccg tctctcaaat ggacgtgcgt tgtttaacct ggtcacaggc agcgatccac
     1921 aagagctggc aggcgacgga gtgttccttg atcatagcga gcgctacgaa gcctcggcgg
     1981 aatttaccca ggtctggcgg cgtttattgc agagagaaac cgtcgatttc aacggtaaac
     2041 atattcatgt gcgcggagca aaactgctct tcccggcgat tcaacagccg tatccgccac
     2101 tttactttgg cggatcgtca gatgtcgccc aggagctggc ggcagaacag gttgatctct
     2161 acctcacctg gggcgaaccg ccggaactgg ttaaagagaa aatcgaacaa gtgcgggcga
     2221 aagctgccgc gcatggacgc aaaattcgtt tcggtattcg tctgcatgtg attgttcgtg
     2281 aaactaacga cgaagcgtgg caggccgccg agcggttaat ctcgcatctt gatgatgaaa
     2341 ctatcgccaa agcacaggcc gcattcgccc ggacggattc cgtagggcaa cagcgaatgg
     2401 cggcgttaca taacggcaag cgcgacaatc tggagatcag ccccaattta tgggcgggcg
     2461 ttggcttagt gcgcggcggt gccgggacgg cgctggtggg cgatggtcct acggtcgctg
     2521 cgcgaatcaa cgaatatgcc gcgcttggca tcgacagttt tgtgctttcg ggctatccgc
     2581 atctggaaga agcgtatcgg gttggcgagt tgctgttccc gcttctggat gtcgccatcc
     2641 cggaaattcc ccagccgcag ccgctgaatc cgcaaggcga agcggtggcg aatgatttta
     2701 tcccccgtaa agtcgcgcaa agctaaggaa gaaataatgg caacgccagt gaagaagtgg
     2761 ttattgcgcg ttgccccctg gtttttaccg gtgggcatcg tggcggtgtg gcaactggcc
     2821 tcctcggttg gctggctgtc gacgcgtatt ttgccttcac cggaaggagt ggtgacggcg
     2881 ttctggacgc tctccgccag cggcgaactg tggcagcatc tggcgatcag ctcctggcgg
     2941 gcgctgattg gcttttcaat tggcggatcg ctggggttga ttttgggact gattagcggg
     3001 ctatctcgct ggggagaacg gctgctggat acctcaattc agatgttgcg caacgtgccg
     3061 catctggcgc tgatcccgct ggtgattttg tggtttggca ttgatgaatc cgcaaaaatc
     3121 tttctggtgg cgctcggtac gctattcccc atttatatca acacctggca tggcatccgt
     3181 aatatcgatc gcgggttggt ggagatggcg cgtagctatg gattatccgg cataccgctg
     3241 tttatccatg tgatcctgcc tggtgccctg ccctcaatta tggtcggcgt gcgttttgcg
     3301 ttgggcctga tgtggctgac gctgattgtt gccgaaacca tttctgccaa ttcaggcatt
     3361 ggttatctgg cgatgaatgc gcgggagttt ttgcaaacgg acgtggtggt agtcgctatt
     3421 attctttacg ccctgctcgg caaactggct gacgtcagcg cgcagctgtt agagcgcctc
     3481 tggttgcgct ggaacccggc ttatcatttg aaggaggcca cggtatgaat actgctcgtc
     3541 tgaaccaggg cacgccattg ttgctcaatg cagtaagcaa acattacgcg gaaaatatcg
     3601 tcctgaacca actggattta catattccgg caggtcagtt tgtggcggtg gtgggccgca
     3661 gcggtggtgg caaaagtacc ctgctgcgcc tgctggcagg tctggaaacg ccaaccgcag
     3721 gcgatgtgtt agcgggcacc acaccgctgg ctgaaattca ggaagacacg cgaatgatgt
     3781 ttcaggatgc gcgtctgcta ccgtggaaat cggtgattga taacgttggg ttaggcctta
     3841 aaggccagtg gcgcgatgcc gcacgtcgag cgttggctgc ggtaggactg gagaatcgcg
     3901 caggggaatg gcctgccgca ctttctggcg ggcagaaaca gcgagtggcg ctggcaagag
     3961 cgttgattca tcgaccggga ttattgttgc ttgatgaacc gctcggggcg ctggacgcct
     4021 taacgcgact cgagatgcag gatttgattg tgtcactttg gcaggagcac ggctttaccg
     4081 tactgttggt gacgcatgat gtgagcgaag cggtagcgat ggctgaccgg gtgctgttaa
     4141 ttgaagaggg aaaaattggt ctggatttga cagtggatat cccccgtccg cgtcgattag
     4201 ggtcggtgcg attagcggag ctggaagcgg aggtgttgca acgggtgatg caacgtggtg
     4261 aatctgaaac tcgcctgaga aaacaggggt aaattccccg aatggcggcg ctattgccgc
     4321 cattcggtta tttatcaagc cagtgcttta gttatcttct cgtacagatc gccagagaga
     4381 ttttccagcc ctttcaactg ttccagcgcc gcgcgcattt tctcctgacg tttggcatcg
     4441 taacgtttca ggcgaatcag cggttcaatc agacgtgaag ccacctgcgg gttacggctg
     4501 ttgaggtcgg taagcatttc caccaggaac aggtaaccgc tgccatcttc ggcatggaac
     4561 gctgccggat tgctgcccgc aaacgcgcca atcaacgaac gaatacggtt cgggttgctc
     4621 atggtaaatg agcgatgctg caacaggccg cgcaccgtct ccagcacatt cgccgccggg
     4681 ctggtggctt gcaggataaa ccatttatcc atcaccagac cgttctgatg ccacttgtcg
     4741 tcgtactcct gcatcagcgc gtcacggcaa ggcagctgtg cggcaaccgc cgcagaaagc
     4801 gccgccagcg catcagtcat attgtttgct tcgtggaact gcttgctcac cagcacatca
     4861 gccagatgcg tttcaccaaa agcgaggaaa cgcaggcagg cattacgcag agtgcgtttt
     4921 gcaatatctt catgctcaac acggtactcg ctctggtaat tcgcgttgta aatagccagt
     4981 agctcatccg ccagttcagt cgccagagta cgagtgagtg cttcgcgtac ttcggcaata
     5041 gcaatcgggt cgatgatatc gaacaattca gccatttcat tgacagaagg cagcgtcagg
     5101 atttctgccg ccagcgctgg atcaatcttc tcatcaagca gtaccgcgcg gaaagcatca
     5161 gccacatgca ccggcagaga cagcggctga ccttgctgat gacgcgcgac gttcagcttg
     5221 atgtaggttg ccagcaaact ttgcgccgca tcccagcggg agaaatcatt acgcgcatga
     5281 cgcatcagga aggtcagttg ctgatcgctc cacttatatt ccagtttcac tggcgcagag
     5341 aattcgcaca gcagcgcagg caccggctgg aagtagacat tatcaaagac aaaggtctgt
     5401 tccgcctgag tgacgttcag cacggaattc accggatgac cgcctttctg caacgggatc
     5461 actttgcctt cgttatcata cagttcgatg gcaaacggaa tatgcagcgg ctgtttttct
     5521 gcctgatccg gcgtggctgg cgtgcgctgg ctgatggtca gggtgtactg ctcggtttcc
     5581 ggattgtagt cgtctttgac ggtcacaatc ggtgtaccgg actggctgta ccaacggcgg
     5641 aaatgggaga gatcgacatt cgacgcatct tccatcgcct gcacaaagtc gtcacaggtc
     5701 gctgcactac catcatgacg ctcgaaataa agctgcatcc ctttctggaa gttttcttcg
     5761 ccaagcaggg tgtggatcat gcgaatcact tccgcgccct tctcgtaaac ggtcagggtg
     5821 tagaagttgt tcatctcaat gaccatatcc gggcggatcg ggtgcgccat cgggctggcg
     5881 tcttctgcaa actgcaatcc gcgcatggtg cgtacattat tgatgcggtt aactgcgcgg
     5941 gaaccaaggt cagagctgaa ctcctgatcg cggaagacgg ttaaaccttc tttcaggctg
     6001 agctggaacc agtcgcgaca ggtcactcgg ttaccggtcc agttatggaa atattcatgg
     6061 ccgataacgc gttcaatatc gaggtaatct ttgtcggtgg cggtgtcggt gcgggccagc
     6121 acatatttgg agttaaagat attcagcccc ttattctcca ttgcgcccat attgaagaaa
     6181 tccaccgcga cgatcatata gatgtcgagg tcatactcca ggccaaagcg ttcttcatcc
     6241 catttcatgg agtttttcag cgaggtcatc gcccacggcg cgcgatcaag gttgccgcga
     6301 tcgacgtaca gctccagtgc tacttcgcga ccagaacgcg tggtaaaggt atcgcgcagt
     6361 acatcaaagt cgcctgccac cagcgcaaac aggtagcacg gtttcgggaa cgggtcctgc
     6421 cactgtaccc aatggcgtcc gttttccagt tcgccttgcg caacgcggtt accattggaa
     6481 agcaggaagg gatatttgat tttatcggca ataattttgg tggtaaaacg cgccagcacg
     6541 tccgggcggt cgagataata cgtaatatgg cggaaacctt cggcttcaca ctgggtgcaa
     6601 agcgcatcgc ctgactgata aagcccttcc agcgcggtat tcgccgccgg gcttatttca
     6661 ttaatgatct taagcgtaaa acgctccggc aaattactga taaccagtgc gccctcttct
     6721 tctttccagg cggtccacgg ctcatcatta atatgaacag aaaccagttt gaggtcttcg
     6781 ccgttgagac gaaggggagc atctgatgca ccatgacgga cagcctggct gaccgcggta
     6841 acgaccgtct tttgcgcgtc gaggtcaaag gtcaagtcaa tatcagtaat ctggtaatcc
     6901 ggcgcacgat aatcgtgacg gtatttggct tgtggctgtt gagtcataaa taacctttag
     6961 catcttttat agagtctggt gttcagtcta ttcctgttgc gtaaatcgcg ctatgcagaa
     7021 tcttcatctt ttcaggtaca aacgccttta ttgctacatt tttataacat acaccgcgta
     7081 atgccatcga ccagaaaggt ggcatatggt gtgatcgggg ttcaataaat tgcgaaacaa
     7141 ggtatactcc agcagttcct gaagatgttt attgtactaa acgctcctgt acgaggacgc
     7201 tactgcgcac ctatgacaca attcgcttct cctgttctgc actcgttgct ggatacagat
     7261 gcttataagt tgcatatgca gcaagccgtg tttcatcact attacgatgt gcatgtcgcg
     7321 gcggagtttc gttgccgagg tgacgatctg ctgggtattt atgccgatgc tattcgtgaa
     7381 caggttcagg cgatgcagca cctgcgcctg caggatgatg aatatcagtg gctttctgcc
     7441 ctgcctttct ttaaggccga ctatcttaac tggttacgcg agttccgctt taacccggaa
     7501 caagtcaccg tgtccaacga taatggcaag ctggatattc gtttaagcgg cccgtggcgt
     7561 gaagtcatcc tctgggaagt tcctttgctg gcggttatca gtgaaatggt acatcgctat
     7621 cgctcaccgc aggccgacgt tgcgcaagcc ctcgacacgc tggaaagcaa attagtcgac
     7681 ttctcggcgt taaccgccgg tcttgatatg tcgcgcttcc atctgatgga ttttggcacc
     7741 cgtcgccgtt tttctcgcga agtacaagaa accatcgtta agcgtctgca acaggaatcc
     7801 tggtttgtgg gcaccagcaa ctacgatctg gcgcgtcggc tttccctcac gccgatggga
     7861 acacaggcac acgaatggtt ccaggcacat cagcaaatca gcccggatct agccaacagc
     7921 cagcgagctg cacttgctgc ctggctggaa gagtatcccg accaacttgg cattgcatta
     7981 accgactgca tcactatgga tgctttcctg cgtgatttcg gtgtcgagtt cgctagtcgg
     8041 tatcagggcc tgcgtcatga ctctggcgac ccggttgaat ggggtgaaaa agccattgca
     8101 cattatgaaa agctgggaat tgatccacag agtaaaacgc tggttttctc tgacaatctg
     8161 gatttacgca aagcggttga gctataccgc cacttctctt cccgcgtgca attaagtttt
     8221 ggtattggga ctcgcctgac ctgcgatatc ccccaggtaa aacccctgaa tattgtcatt
     8281 aagttggtag agtgtaacgg taaaccggtg gcgaaacttt ctgacagccc tggcaaaact
     8341 atctgccatg ataaagcgtt tgttcgggcg ctgcgcaaag cgttcgacct tccgcatatt
     8401 aaaaaagcca gttaatatca tcagggagct aatcggctcc ctttttttac ctttaattcc
     8461 gaaatctttc gctgcatttg cgaattctgc ttgtctgatt gcagatgcca ggtaacatag
     8521 gtatcccccc atttacgggt ggacaagtgt ttattttttc cgactattaa cagagagaat
     8581 attatgagcg ttgtgcctgt agccgacgta ctccagggcc gtgtagccgt tgacagcgaa
     8641 gtcaccgtgc gcggatgggt acgtacccgc cgagattcaa aagctggcat ctccttcctc
     8701 gccgtttatg acggttcctg ctttgatcct gtacaggctg tcatcaataa ttctctgccc
     8761 aattacaatg aagacgtcct gcgtctgacc accggctgct cggtcattgt gacgggtaaa
     8821 gtcgtggcgt cgccgggcca ggggcaacaa tttgaaattc aggccagcaa ggttgaagtt
     8881 gctggttggg ttgaagatcc agacacttac ccgatggcgg caaaacgcca cagcattgag
     8941 tatctgcgtg aagtcgctca cctgcgtccg cgcacaaacc tgattggtgc cgtcgcgcgc
     9001 gttcgccata cgctggcgca ggcgctgcat cgcttcttta acgagcaggg attcttctgg
     9061 gtttcaacgc cactgattac cgcatctgat accgaaggtg caggcgaaat gttccgcgtt
     9121 tctacgctgg atctggaaaa cctgccgcgt aacgatcagg gcaaagtgga tttcgacaaa
     9181 gacttctttg gtaaagagtc tttcctgacc gtatctggcc agttgaacgg cgaaacctac
     9241 gcttgcgcat tgtccaaaat ttataccttc ggcccgactt tccgtgctga aaactccaac
     9301 accagccgtc acctagcgga attctggatg ctggagccgg aagtggcgtt tgctaacctg
     9361 aacgatattg cgggtctggc tgaagccatg ctgaaatatg tcttcaaagc ggttctcgaa
     9421 gaacgcgctg acgacatgaa attcttcgct gaacgcgtag ataaagatgc cgtttcacgt
     9481 ctggaacgct tcattgaagc cgattttgcg caggtggatt ataccgacgc agtgaccatt
     9541 ctcgaaaact gcggcaggaa gtttgaaaac ccggtttact ggggagtcga tctctcttct
     9601 gagcatgagc gttatctggc ggaagaacac tttaaagcac cggtagtggt taaaaactat
     9661 ccgaaagata ttaaagcgtt ctatatgcgc cttaacgaag acggtaaaac cgttgcggct
     9721 atggacgttc tggctccggg catcggtgag atcattggtg gctcccagcg tgaagaacgt
     9781 ctggacgtgc tggacgagcg tatgctggaa atgggcctga ataaagaaga ttactggtgg
     9841 tatcgcgatc tgcgtcgcta cggtactgtt ccgcattcag gtttcggtct tggttttgaa
     9901 cgtctgattg cttacgtaac tggcgtgcaa aacgtacgtg atgtgattcc gttcccacgt
     9961 actccgcgta acgccagctt ctaatttagc gtcttcaaga gccagcgccc gctggctctt
    10021 tttttatctt ttctgtcaag ttatctgttt gttaagtcaa gcaatctatt tgcaaccccg
    10081 ccataacgat catcctgtta cggaatatta cattgcaaca tttacgcgca aaaactaatc
    10141 cgcattctta ttgcggatta gttttttctt agctaatagc acaattttca tactattttt
    10201 tggcattctg gatgtctgaa agaagatttt gtgccaggtc gataaagttt ccatcagaaa
    10261 ca
//
LOCUS       DAPHKZ010000149         9950 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.150, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000149 DAPHKZ010000000
VERSION     DAPHKZ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9950
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.150"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            532..2100
                     /gene="cydA"
                     /locus_tag="RH288_004005"
     CDS             532..2100
                     /gene="cydA"
                     /locus_tag="RH288_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415261.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HDV4033011.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPD
                     QEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSSTTTQPAR"
     gene            2116..3255
                     /gene="cydB"
                     /locus_tag="RH288_004006"
     CDS             2116..3255
                     /gene="cydB"
                     /locus_tag="RH288_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDV4033012.1"
                     /translation="MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGN
                     FFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALA
                     GVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLP
                     LLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     LTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY"
     gene            3270..3383
                     /gene="cydX"
                     /locus_tag="RH288_004007"
     CDS             3270..3383
                     /gene="cydX"
                     /locus_tag="RH288_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HDV4033013.1"
                     /translation="MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI"
     gene            3383..3676
                     /gene="ybgE"
                     /locus_tag="RH288_004008"
     CDS             3383..3676
                     /gene="ybgE"
                     /locus_tag="RH288_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HDV4033014.1"
                     /translation="MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTS
                     ELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF"
     gene            3826..4230
                     /gene="ybgC"
                     /locus_tag="RH288_004009"
     CDS             3826..4230
                     /gene="ybgC"
                     /locus_tag="RH288_004009"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HDV4033015.1"
                     /translation="MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENT
                     LLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ"
     gene            4227..4919
                     /gene="tolQ"
                     /locus_tag="RH288_004010"
     CDS             4227..4919
                     /gene="tolQ"
                     /locus_tag="RH288_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HDV4033016.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            4923..5351
                     /gene="tolR"
                     /locus_tag="RH288_004011"
     CDS             4923..5351
                     /gene="tolR"
                     /locus_tag="RH288_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HDV4033017.1"
                     /translation="MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKAN
                     PKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            5416..6681
                     /gene="tolA"
                     /locus_tag="RH288_004012"
     CDS             5416..6681
                     /gene="tolA"
                     /locus_tag="RH288_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HDV4033018.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGG
                     GGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQER
                     LKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAA
                     KKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK
                     AKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAA
                     AAKAAAEKAAAAKAAAEADDIFGELSSGKNAPKTGGGAKGNNASPAGSGNTKNNGASG
                     ADINNYAGQIKSAIESKFYDASSYAGKTCTLRIKLAPDGMLLDIKPEGGDPALCQAAL
                     AAAKLAKIPKPPSQAVYEVFKNAPLDFKP"
     gene            6814..8106
                     /gene="tolB"
                     /locus_tag="RH288_004013"
     CDS             6814..8106
                     /gene="tolB"
                     /locus_tag="RH288_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HDV4033019.1"
                     /translation="MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVG
                     QVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLA
                     SGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQN
                     QDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL"
     gene            8141..8662
                     /gene="pal"
                     /locus_tag="RH288_004014"
     CDS             8141..8662
                     /gene="pal"
                     /locus_tag="RH288_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HDV4033020.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMD
                     ANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYK
                     VTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDE
                     AAYSKNRRAVLVY"
     gene            8672..9463
                     /gene="cpoB"
                     /locus_tag="RH288_004015"
     CDS             8672..9463
                     /gene="cpoB"
                     /locus_tag="RH288_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HDV4033021.1"
                     /translation="MSSNFRHQLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVVERQKQILLQIDSLS
                     SGGAAAQSTSSDQSGAAASTTPTADAGTANAGAPVKSGDANTDYNAAIALVQDKSRQD
                     DAMVAFQNFIKNYPDSTYLPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAAD
                     AMFKVGVIMQDKGDTAKAKAVYQQVISKYPGTDGAKQAQKRLNAM"
     gene            9628..9703
                     /locus_tag="RH288_004016"
     tRNA            9628..9703
                     /locus_tag="RH288_004016"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9661..9663,aa:Lys,seq:ttt)
     gene            9839..9914
                     /locus_tag="RH288_004017"
     tRNA            9839..9914
                     /locus_tag="RH288_004017"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9872..9874,aa:Val,seq:tac)
BASE COUNT         2446 a         2362 c         2681 g         2461 t
ORIGIN      
        1 actctgcgtc gtattagcca gtgaccaaaa aaagaattaa ggtcaaccgt gctgtttttg
       61 cttcgtctct ttttatcttt aattgccaac cgaaactaat ttcagcctta taactcacac
      121 attttaaaca taaatgtcac taaagttacc ttattgaaac atgattaaca taatttgtag
      181 gaattgatat ttatcaatgt ataagtcttg gaaatgggca tcaaaaagag ataaattgtt
      241 ctcgatcaaa ttggctgaaa ggcggtaatt tagctataaa ttgatcaccg tcgaaaaatg
      301 caaatttgct tcaacaaaaa cctgtttatt gtaaggattt tgcggcgtaa tatatacgtg
      361 ggatcaattt gagtttttat taacatgttt gcaacctttc tttacgccgt ttttgtgtgc
      421 attcacatgg tatgatgaaa gtgttcaaac aaatttctat tggggcatgc gtgtgaccct
      481 ttctaacggg gttcactctc ggagtcttca tgcgatgagc aaggagtcat gatgttagat
      541 atagtcgaac tgtcgcgctt acagtttgcc ttgaccgcga tgtaccactt cctttttgtg
      601 ccactgacgc tcggtatggc gttcctgctg gccattatgg aaacggtcta cgtcctctcc
      661 ggcaaacaga tttataaaga tatgaccaag ttctggggca agttgtttgg tatcaacttc
      721 gctctgggtg tggctaccgg tctgaccatg gagttccagt tcgggactaa ctggtcttac
      781 tattcccact atgtagggga tatcttcggt gcgccgctgg caatcgaagg tctgatggcc
      841 ttcttcctcg aatccacctt tgtaggtctg ttcttcttcg gttgggatcg tctgggtaaa
      901 gttcagcata tgtgtgtcac ctggctggtg gcgctcggtt caaacctgtc cgcactgtgg
      961 attctggttg cgaacggctg gatgcaaaac ccaatcgcgt ccgatttcaa ctttgaaact
     1021 atgcgtatgg agatggtgag cttctccgag ctggtgctta acccggttgc tcaggtgaaa
     1081 ttcgttcaca ctgtagcgtc tggttatgtg actggcgcga tgttcatcct cggtatcagc
     1141 gcatggtata tgctgaaagg tcgtgacttc gccttcgcta aacgctcctt tgctatcgct
     1201 gccagcttcg gtatggctgc tgttctgtct gttattgttc tgggtgatga atccggctac
     1261 gaaatgggcg acgtgcagaa aaccaaactg gctgctattg aagccgagtg ggaaacgcaa
     1321 cctgcgcctg ctgcctttac tctgttcggc attcctgatc aggaagagga gacgaacaaa
     1381 tttgcgattc agatccctta cgcactgggc atcattgcaa cgcgttccgt ggataccccg
     1441 gttatcggcc tgaaagagct gatggtgcag catgaagaac gcattcgtaa cgggatgaag
     1501 gcgtactctc tgctcgaaca actgcgttct ggttctaccg accaggcggt tcgtgaccag
     1561 ttcaatagca tgaagaaaga cctcggttac ggtctgctgc tgaaacgcta tacgccaaac
     1621 gtggctgatg cgactgaagc gcagattcaa caggcaacca aagactccat cccgcgtgta
     1681 gcgccgctgt actttgcgtt ccgtatcatg gtggcgtgtg gcttcctgct tctggcaatc
     1741 atcgcgctct ctttctggag tgtcatccgc aaccgcattg gcgagaaaaa atggcttctg
     1801 cgcgccgcgc tgtacggtat tccgctgccg tggattgctg tagaagcggg ctggttcgtg
     1861 gctgaatatg gccgccaacc gtgggctatc ggtgaagtgc tgccgacagc tgtggcgaac
     1921 tcgtcactga ccgcaggcga tctcatcttc tcaatggtgc tgatttgcgg cctgtatacc
     1981 ctgttcctgg tggcagaatt gttcttaatg ttcaagtttg cacgcctcgg cccaagcagc
     2041 ctgaaaaccg gtcgctatca ctttgagcag tcttccacga ctactcagcc ggcacgctaa
     2101 gacaggagtc gtcaaatgat cgattatgaa gtattgcgtt ttatctggtg gctgctggtt
     2161 ggcgttctgc tgattggttt tgcagtcact gacggtttcg acatgggggt gggcatgctc
     2221 acccgtttcc tcggtcgtaa cgacaccgag cgtcgaatta tgattaactc cattgcacca
     2281 cactgggacg gtaaccaggt ttggctgatc accgcgggcg gcgcactctt tgctgcctgg
     2341 ccgatggtct atgccgctgc gttctccggc ttctatgtgg cgatgatcct cgtgctggcg
     2401 tctttgttct tccgtccggt cggttttgac taccgctcca agattgaaga aacccgctgg
     2461 cgtaacatgt gggactgggg catcttcatt ggtagcttcg ttccgccgct ggtaattggt
     2521 gtagcgttcg gtaacctgtt gcagggcgta ccgttcaacg ttgatgaata tctgcgtctg
     2581 tactacaccg gtaacttctt ccagttgctt aacccgttcg gcctgctggc aggcgtggtg
     2641 agcgtaggga tgatcattac tcagggcgca acctatctgc aaatgcgtac cgtgggcgaa
     2701 ctgcacctgc gtacccgtgc aacggctcag gtggctgcgc tggtgacact ggtctgtttc
     2761 gcactggctg gcgtatgggt gatgtacggt atcgatggtt atgtcgtgaa atcgacaatg
     2821 gaccattacg cagcctctaa cccactgaat aaagaagtgg ttcgtgaagc tggcgcatgg
     2881 ctggttaact tcaacaacac gccaattctg tgggctattc cggcactggg tgtggttctg
     2941 ccgctgctga ccatcctgac tgcacgtatg gataaagccg cgtgggcgtt tgtgttctcc
     3001 tccctgacgc tggcctgcat catcctgaca gccggtatcg caatgttccc gtttgtgatg
     3061 ccgtccagca ccatgatgaa cgcaagtctg acaatgtggg atgcaacttc cagccagctg
     3121 acgcttaacg tcatgacctg ggttgcggtg gttctggtac cgatcattct gctctacacc
     3181 gcctggtgtt actggaaaat gttcggtcgt atcaccaaag aagatattga acgtaacacc
     3241 cactctctgt actaagtaag gagctaaaaa tgtggtattt cgcatggatt ctgggaacgc
     3301 ttcttgcctg ttcgtttggg gtaatcaccg cgctggcgct tgaacacgtc gaatcaggca
     3361 aagccggtca agaagacatc tgatgagtaa gattatcgcg actttgtatg cggtaatgga
     3421 caagcgcccc ctgcgggcgc tttccttcgt gatggcgctt ctgttagcag gatgtatgtt
     3481 ttgggaccca tctcgttttg ccgcgaagac cagtgaactg gaaatctggc atggtttatt
     3541 gctgatgtgg gccgtctgtg ctggtgtgat tcacggcgtg ggctttcgtc cgcagaaggt
     3601 tctttggcaa gggatttttt gcccattgct tgccgatatt gttctcattg tcgggctgat
     3661 tttcttcttc ttttaaatca gaattctctt taaaaaatta tgggccgctc caggcccata
     3721 aatttttacg ctcccttaac ttgccctcat tcccaaacct caatcgcgcg cgtatagtag
     3781 cagcgtttaa aagctctaac ttttgttgca ttaccgggat gtaaagtgaa tacaacgctg
     3841 tttcgatggc cggttcgcgt ctactatgaa gataccgatg ccggtggtgt ggtgtaccac
     3901 gccagttacg tcgcttttta tgaaagagca cgcacagaga tgctgcgtca tcatcacttc
     3961 agtcagcagg cgctgatggc tgaacgcgtt gcctttgtgg tacgtaaaat gacggtggaa
     4021 tattacgcac ctgcgcggct cgacgatatg ctcgaaatac agactgaaat aacatcaatg
     4081 cgtggcacct ctttggtttt cacgcaacgt attgtcaacg ccgagaatac tttgctgaat
     4141 gaagcagagg ttctggttgt ttgcgttgac ccactcaaaa tgaagcctcg tgcgcttccc
     4201 aagtctattg tcgcggagtt taagcagtga ctgacatgaa tatccttgat ttgttcctga
     4261 aggctagcct tctggttaaa cttatcatgt tgattttgat tggtttttca atcgcatctt
     4321 gggccattat tatccagcgg acccgtattc ttaacgcagc ggcgcgcgaa gccgaagcgt
     4381 ttgaagataa attctggtct ggaatcgaac tctctcgcct ctatcaagag agccagggga
     4441 aacgggataa tctgactggt tcggaacaaa tcttttacag cgggttcaaa gagtttgtgc
     4501 gcctgcatcg tgccaatagc catgcgccgg aagccgtagt ggaaggggcg tcgcgtgcta
     4561 tgcgtatctc catgaaccgt gaacttgaaa atctggaaac gcacattccg ttcctcggta
     4621 cggttggctc catcagcccg tatattggtc tgtttggtac ggtctggggg atcatgcacg
     4681 cctttatcgc cctcggggcg gtaaaacaag caacactgca aatggttgcg cccggtatcg
     4741 cagaagcgtt gattgcgact gcaattggtc tgtttgccgc tatcccggca gttatggcct
     4801 acaaccgcct caaccagcgc gtaaacaaac tggaactgaa ttacgacaac tttatggaag
     4861 agtttaccgc gattctgcac cgccaggcgt ttaccgttag cgagagcaac aaggggtaag
     4921 ccatggccag agcgcgtgga cgaggtcgtc gcgatctcaa gtccgaaatc aacattgtac
     4981 cgttgctgga cgtactgctg gtgctgttgc tgatctttat ggcgacagcg cccatcatca
     5041 cccagagcgt ggaggtcgat ctgccagacg ctactgaatc acaggcggtg agcagtaacg
     5101 ataatccgcc agtgattgtt gaagtgtctg gtattggtca gtacaccgtg gtggttgaga
     5161 aagatcgcct ggagcgttta ccaccagagc aggtggtggc ggaagtgtcc agccgtttca
     5221 aggccaaccc gaaaacggtc tttctgatcg gtggcgcaaa agatgtgcct tacgatgaaa
     5281 taattaaagc actgaacttg ttacatagtg cgggtgtgaa atcggttggt ttaatgacgc
     5341 agcctatcta aacatctgcg tttcccttgc ttgaaagaga gcgggtaaca ggcgaacagt
     5401 ttttggaaac cgagagtgtc aaaggcaacc gaacaaaacg acaagctcaa gcgggcgata
     5461 attatttcag cagtgctgca tgtcatctta tttgcggcgc tgatctggag ttcgttcgat
     5521 gagaatatag aagcttcagc cggaggcggc ggtggttcgt ccatcgacgc tgtcatggtt
     5581 gattcaggtg cggtagttga gcagtacaaa cgcatgcaaa gccaggaatc aagcgcgaag
     5641 cgttctgatg aacagcgcaa gatgaaggaa cagcaggctg ctgaagaact gcgtgagaaa
     5701 caagcggctg aacaggaacg cctgaagcaa cttgagaaag agcggttagc ggctcaggag
     5761 cagaaaaagc aggctgaaga agccgcaaaa caggccgagt taaagcagaa gcaagctgaa
     5821 gaggcggcag cgaaagcggc ggcagatgct aaagcgaagg ccgaagcaga tgctaaagct
     5881 gcggaagaag cagcgaagaa agcggctgca gacgcaaaga aaaaagcaga agcagaagcc
     5941 gccaaagccg cagccgaagc gcagaaaaaa gccgaggcag ccgctgcggc actgaagaag
     6001 aaagcggaag cggcagaagc agctgcagct gaagcaagaa agaaagcggc aactgaagct
     6061 gctgaaaaag ccaaagcaga agctgagaag aaagcggctg ctgaaaaggc tgcagctgat
     6121 aagaaagcgg cagcagagaa agctgcagcc gacaaaaaag cagcagaaaa agcggctgct
     6181 gaaaaggcag cagctgataa gaaagcagcg gcagaaaaag ccgccgcaga caaaaaagcg
     6241 gcagcggcaa aagctgcagc tgaaaaagcc gctgcagcaa aagcggccgc agaggcagat
     6301 gatattttcg gtgagctaag ctctggtaag aatgcaccga aaacgggggg aggggcgaaa
     6361 gggaacaatg cttcgcctgc cgggagtggt aatactaaaa acaatggcgc atcaggggcc
     6421 gatatcaata actatgccgg gcagattaaa tctgctatcg aaagtaagtt ctatgacgca
     6481 tcgtcctatg caggcaaaac ctgtacgctg cgcataaaac tggcacccga tggtatgtta
     6541 ctggatatca aacctgaagg tggcgatccc gcactttgtc aggctgcgtt ggcagcagct
     6601 aaacttgcga agatcccgaa accaccaagc caggcagtat atgaagtgtt caaaaacgcg
     6661 ccattggact tcaaaccgta atcgcgatgt tgactgttcg gacggtcaac atcaggcacc
     6721 ggttgccacg gggttctggt agttttgtgt attttagttt gttaacattc tgctaaatta
     6781 tcgtgggcca tcggtccaga taagggagat atgatgaagc aggcattacg agtagcattt
     6841 ggttttctca tactgtgggc atcagttctg catgctgaag tccgcattgt gatcgacagc
     6901 ggtgtagatt ccggtcgtcc tattggtgtt gttcctttcc agtgggcggg gcctggtgcg
     6961 gcacctgaag atattggcgg catcgttgct gctgacttgc gtaacagcgg taaatttaat
     7021 ccgttagatc gcgctcgtct gccacagcag ccgggtagtg cgcaggaagt acaaccagct
     7081 gcatggtccg cactgggcat tgacgctgta gttgtcggtc aggtcactcc gaatccggat
     7141 ggttcttaca atgttgctta tcaacttgtt gacactggcg gcgcaccggg tactgtactt
     7201 gctcagaact cgtacaaagt gaacaagcag tggctgcgtt atgctggtca taccgccagt
     7261 gatgaagtgt ttgaaaaact gaccggcatt aaaggtgcgt tccgtactcg tattgcctac
     7321 gttgttcaga ccaacggcgg tcagttcccg tatgaactgc gcgtatctga ctatgacggt
     7381 tacaaccagt ttgtcgttca ccgttcaccg cagccgctga tgtctccggc gtggtcacca
     7441 gacggttcta aactggctta tgtgaccttc gaaagcggtc gttccgcgct ggttattcag
     7501 acgctggcaa atggcgctgt acgtcaggtg gcttcattcc cgcgtcacaa cggtgcacct
     7561 gcattctcgc cagacggcag caaactggca ttcgccttgt cgaaaaccgg tagtctgaac
     7621 ctgtacgtaa tggatttggc ttctggtcag atccgccagg tgactgatgg tcgcagtaac
     7681 aataccgaac cgacctggtt cccggatagc cagaacctgg catttacttc tgaccaggcc
     7741 ggtcgtccgc aggtttataa agtgaatatc aacggcggtg cgccacaacg tattacctgg
     7801 gaaggttcgc agaaccagga tgcggatgtc agcagcgacg gtaaatttat ggtaatggtc
     7861 agctccaatg gtgggcagca gcacattgcc aaacaagatc tggcaacggg aggcgtacaa
     7921 gttctgtcgt ccacgttcct ggatgaaacg ccaagtctgg cacctaacgg cactatggta
     7981 atctacagct cttctcaggg gatgggatcc gtgctgaatt tggtttctac agatgggcgt
     8041 ttcaaagcgc gtcttccggc aactgatgga caggtcaaat tccctgcctg gtcgccgtat
     8101 ctgtgataat aattaattga atagtaaagg aatcattgaa atgcaactga acaaagtgct
     8161 gaaagggctg atgattgctc tgcctgttat ggcaattgcg gcatgttctt ccaacaagaa
     8221 cgccagcaat gacggcagcg aaggcatgct gggtgccggc actggtatgg atgcgaacgg
     8281 cggcaacggc aacatgtctt ccgaagagca ggctcgtctg caaatgcaac agctgcagca
     8341 gaacaacatc gtttacttcg atctggacaa gtacgatatc cgttctgact tcgctcaaat
     8401 gctggatgca catgcaaact tcctgcgtag caacccgtct tacaaagtca ccgtagaagg
     8461 tcacgcggac gaacgtggta ctccggaata caacatctcc ctgggtgaac gtcgtgcgaa
     8521 cgccgttaag atgtacctgc agggtaaagg cgtttctgca gaccagatct ccatcgtttc
     8581 ttacggtaaa gaaaaacctg cagtactggg tcatgacgaa gcggcatact ccaaaaaccg
     8641 tcgtgcggta ctggtttact aagagaattg catgagcagt aacttcagac atcaactatt
     8701 gagtctgtcg ttactggttg gtatagcggc cccctgggcc gcttttgctc aggcaccaat
     8761 cagtagtgtc ggctcaggct cggtcgaaga ccgcgtcact caacttgagc gtatttctaa
     8821 tgctcacagc cagcttttaa cccaactcca gcaacaactt tctgataatc aatccgatat
     8881 tgattccctg cgtggtcaga ttcaggaaaa tcagtatcaa ctgaatcagg tcgtggagcg
     8941 gcaaaagcag atcctgttgc agatcgacag cctcagcagc ggtggtgcag cggcgcaatc
     9001 aaccagcagc gatcaaagcg gtgcggcggc atcaacgacg ccgacagctg atgctggtac
     9061 tgcgaatgct ggcgcgccgg tgaaaagcgg cgatgcaaac acggattaca atgcagctat
     9121 tgcgctggtg caggataaat cccgccagga tgacgcaatg gtggcatttc agaatttcat
     9181 caaaaattac cctgattcaa cttacctgcc aaacgccaat tattggctgg gtcagttaaa
     9241 ctacaacaag ggtaaaaaag atgatgcggc gtactatttt gcttcggtag tgaaaaacta
     9301 tccgaagtca ccaaaggctg ctgatgcgat gtttaaagtc ggcgtcatca tgcaggacaa
     9361 aggtgacacc gcaaaagcga aagccgtata ccagcaggtt atcagtaaat accctggtac
     9421 tgatggcgct aaacaggcac aaaaacgtct gaacgcgatg taatgcataa cacacgacca
     9481 gaagtcgcat tatttctggt cgtgtcgtgc gaatcataag cagttgagtg atctgcatcg
     9541 aaatttttgt tgcgctcaag tctgaaatca gtaatatatg ccgccgttgc cacgggatat
     9601 caaacaaacc gaaagcaacg aaaaagtggg tcgttagctc agttggtaga gcagttgact
     9661 tttaatcaat tggtcgcagg ttcgaatcct gcacgaccca ccaatcgcta aggtggaagc
     9721 ggtagtaaaa cgtgaaggat aacgttgcat cagcaacggc ccgaagggcg agacgaagtc
     9781 gagtcatcct gcacgaccca ccactaacat agttagttgt agtatccagc gtagtattgg
     9841 gtgattagct cagctgggag agcacctccc ttacaaggag ggggtcggcg gttcgatccc
     9901 gtcatcaccc accaccgggt cgttagctca gttggtagag cagttgactt
//
LOCUS       DAPHKZ010000150         9904 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.151, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000150 DAPHKZ010000000
VERSION     DAPHKZ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9904
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.151"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..141)
                     /locus_tag="RH288_004018"
     CDS             complement(<1..141)
                     /locus_tag="RH288_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033022.1"
                     /translation="MLQSSADKACNVLVKKVRYLKDVRKITKMMNGKLIYSWLKWPCG
                     EFF"
     gene            219..1313
                     /gene="ddlA"
                     /locus_tag="RH288_004019"
     CDS             219..1313
                     /gene="ddlA"
                     /locus_tag="RH288_004019"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDV4033023.1"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     gene            complement(1337..1549)
                     /locus_tag="RH288_004020"
     CDS             complement(1337..1549)
                     /locus_tag="RH288_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 domain-containing protein"
                     /protein_id="HDV4033024.1"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     gene            1809..2117
                     /locus_tag="RH288_004021"
     CDS             1809..2117
                     /locus_tag="RH288_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HDV4033025.1"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     gene            complement(2176..3270)
                     /gene="yaiW"
                     /locus_tag="RH288_004022"
     CDS             complement(2176..3270)
                     /gene="yaiW"
                     /locus_tag="RH288_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HDV4033026.1"
                     /translation="MSRVNPLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLISMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAGKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     gene            complement(3283..4503)
                     /gene="sbmA"
                     /locus_tag="RH288_004023"
     CDS             complement(3283..4503)
                     /gene="sbmA"
                     /locus_tag="RH288_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706191.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HDV4033027.1"
                     /translation="MFKSFFPKPGAFFLSAFVWALIAVIFWQAGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFAFFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSTHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     gene            4855..6012
                     /gene="ampH"
                     /locus_tag="RH288_004024"
     CDS             4855..6012
                     /gene="ampH"
                     /locus_tag="RH288_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HDV4033028.1"
                     /translation="MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVVRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYPRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     gene            complement(6013..6636)
                     /gene="iprA"
                     /locus_tag="RH288_004025"
     CDS             complement(6013..6636)
                     /gene="iprA"
                     /locus_tag="RH288_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HDV4033029.1"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNSEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     gene            complement(6724..9687)
                     /locus_tag="RH288_004026"
     CDS             complement(6724..9687)
                     /locus_tag="RH288_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000556401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV4033030.1"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANATTYNTWTYYDNPTTALD
                     WSNMDLPGTVDGNYVNYSGFVYYNNTNGDFDTTFNGDTVNGAISTYYLNHDFTDGTTN
                     QLNISNSLIHGSITSMLPMGESSDGHYVYQFSEYGTDRVIDDNWHDGDVFTLNIANST
                     IDDDYEGLYFTDSYLNGDVTKYTNETFRTPAGEGEEYAGLFANGGVGLGLAVNLDVES
                     NINISNNSRVAGISLTQGNTVNNTYTTESHTWDNNISVIDSTVTSGSVTTLEDSGFYG
                     NSAEPSDYSGKGGANDVALYFSDSAASNYSMKNNVYFSNSTLLGDVVFASTFNANFYP
                     HGHDSNADGVLDTNGGWADDSLNVDELNITLDNGSKWVGSATTSANVDVDSTVSTDWY
                     DVTGNSLYPGVVAEDNAWGRTIDNQVFQSGVFNVTLNNGSEWNTVNASNIDTLAINNG
                     SEVNVTNSSLLSDTIGLTNGSSLNIGEDGEVATDHLTVDSYSTVNLTESTGWNNYSNL
                     YANTITVTNGGVLDVNVDQFDTEAFRTDKLELTSGNIADHNGNVVSGVFNIHSSDYVL
                     NADLVNDRTWDTSKSNYGYGIVAMNSDGHLTINGNGDVDNGTELDNSSVDNVVAATGN
                     YKVRIDNATGAGSIADYNGNELIYVNDKNSNATFSAANKADLGAYTYQAEQRGNTVVL
                     QQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVSYFGGNFNG
                     DNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVDQDSQTAYI
                     YSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKAGYDFKLGD
                     AGYVTPYGSISGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYTFTYSEDQALTP
                     YFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTDANYLGGGD
                     VDQDWSANVGVKYTW"
BASE COUNT         2603 a         2438 c         2316 g         2547 t
ORIGIN      
        1 aaaaaactca ccgcatggcc atttaagcca ggaataaatt agcttcccgt tcatcatttt
       61 tgtgatcttg cgcacatctt tgagataacg cactttcttc accagtacgt tgcacgcttt
      121 gtcagcagaa gattgcaaca atctttcaga aggccgcgaa tcccccgttt tgtcgtggta
      181 atgtatgcac tttgtgttag acgggatagg tttttaagat ggaaaaactg cgggtaggaa
      241 tcgtttttgg tggtaaatca gcggaacatg aagtgtctct gcaatcggca aaaaacattg
      301 tcgatgccat tgataaaagt cgcttcgacg ttgtgctgct gggcattgat aaacaagggc
      361 aatggcacgt cagcgatgcc agcaattatc tgctaaatgc agacgatcct gcccatattg
      421 cgttgcgccc ttcggcgacc agccttgcgc aggtgccagg taaacatgag catcagctta
      481 tcgacgcgca aaacggtcag ccgttgccga cggtggatgt cattttcccg attgtccacg
      541 gtacgctggg cgaagatggt tccttgcagg gaatgctgcg ggtcgccaat ttaccgtttg
      601 taggttctga tgttctggct tcagcagcct gtatggataa agatgtcacc aaacgtctgc
      661 tacgcgatgc cgggctgaac attgcgccat ttattaccct gacgcgcgct aatcgtcaca
      721 acatcagttt tgccgaagtg gagtctaaac tggggttacc actgtttgta aaaccggcta
      781 atcagggctc ttctgttggt gtcagcaaag taaccagtga agaacagtac gcaattgccg
      841 tcgatctggc gttcgaattc gatcataaag tgatcgttga gcaagggatc aaaggtcgtg
      901 agatcgaatg cgcagttctg ggcaacgaca acccgcaagc cagcacctgt ggcgagatcg
      961 tactcaccag cgacttctat gcctacgaca ccaagtacat tgacgaagat ggcgcgaaag
     1021 tggtagttcc ggcagccatt gcaccagaga tcaacgataa gatccgggcg attgccgttc
     1081 aggcttatca gacgttggga tgcgcaggca tggcgcgtgt agacgtgttt ttaaccccag
     1141 agaacgaagt ggtgatcaac gagatcaaca cactgcctgg cttcaccaac atcagtatgt
     1201 atccgaagct gtggcaagcc agcggtctgg gttacaccga tctgatcaca cgtttgattg
     1261 agctggcgct ggagcgtcac gctgcggata acgcattgaa aaccacaatg taatatttta
     1321 acgcccgata atattcttat tgggcgtttt cagtttcttc atcgcgacga cgaataatca
     1381 accccgccag ccagaaacta atcacccacg tcaccagacc gacggcatag gtctgccaac
     1441 cttttgcttc aaatcccagt aaccccacca cgccattaag aatgaatata aggccaatgg
     1501 cgaacgcata gtagtgccag tcacggcgga tttttacagg cagattcatg gcagctccgt
     1561 taacgaaaaa caacatcctt gcatattctg taacaaccgt ctgtggtgta gacaacattt
     1621 tcgtaattgt taataaattt aacttaaggt tgccattttg tgactcacaa cgaagattca
     1681 cgcttcggga atattcccaa catcaattta ccatgattct gatattgaca atctaaatga
     1741 cctgtcagac ttgccataag ccgctggtat cacaccagaa gagaagcaga tgacttccgg
     1801 aggtttttat ggctgatttc accctgtcaa aatcgctgtt tagcggaaaa tatcgcaatg
     1861 cctcttcaac gcctggcaac attgcctatg cgttgtttgt gctgttttgc ttttgggctg
     1921 gggcgcaatt gctgaacctg ttagtgcatg cgcccggcgt ctatgagcgt ttaatgcagg
     1981 tccaggaaac aggtcgccca cgggtggaaa ttggtttagg tgtcggcacc attttcgggc
     2041 tgatcccgtt tttagtaggc tgcctcattt ttgcagtggt ggcgctatgg ctgcactggc
     2101 gacatcgccg ccagtaagat ttacgttgcc agatacggcc taaaacgcct tatctggcat
     2161 gacattcctg tttgatcact gtttcataca acgcgcccgc cgttcgtcta cgcgcttcgc
     2221 aaaccaggcc gtagtcaggt tgcgggtgat tttcgggctt tccagttgaa tgccaggcaa
     2281 catttcgcgg ggtagtgatt tacccgtttt cgcttcggca agttgataaa ctttcttgta
     2341 cagcgccgtc tcctcaaaag agaagctgtc acctttctct aactgacggc gaatttcgct
     2401 gtcgctcatc cccagttttc ccgccagttt gcgcgttgcc agttcggttt tcccgggttc
     2461 tttactgtcg taacgaatta aatcaccgtc cagtgccagc ttcacgccgc tggccttact
     2521 gactgcgttc tgaaacgcgg cattacggct ggcgtaccag ccagcgttaa aatcagcaaa
     2581 gcggtatatc ggtgcgctat agctggcggg ataattcagt aaatggtaag taccaaacca
     2641 caacccgccg cggcgactga agacttcctg acgaactgta ccgtccattt tccacggata
     2701 ccctttggta tgctgttcgg caaaagcaat gctgacctgc atcggcccac cggtgcgcac
     2761 cggattaagc gaaccaaaca gcgtctgccc cattggtacc atgctgatca gatcgtcaaa
     2821 aatcgcgctc aattgctttt ctgtacgcac cgaatctaac cgttcgctat aacttttgcc
     2881 gtttggcgat ttgattttta gcgcggtatg aaccagaaaa gcaggaatgt gcatccgttc
     2941 agcacgacgg tcaatctctt gccaggcgat cttgcttaag cccggaacgg ccggatctgc
     3001 ctgataattt gactcctgct gcgccaccgc cagcaccgag cagacgtttt ccagcgtcgg
     3061 tgccagcccc tgactttcaa aggtggtggc gagatctttc gcccaggcat cgcggtcttt
     3121 cacgctcgca ggcatcttct gccgcacgac gctcgccaca tctatcgctt tttcgccctt
     3181 tttcaacggt tgcggagcct gactactaca ccccgctaaa accagaaccg ccaacaatga
     3241 cagcgaagat agaggattga cgcgcgacat tacttctcct ttttagctca aggtatgggt
     3301 tacttcctga attttgtcac catccagttc atgttcaaag ctgcgcagac gtttgtagat
     3361 agacatcaac tcaaccagtg tggtccatga gttaatcagg tactggaaag caccgcgaac
     3421 ctgaccaaaa acgttggtaa tctgcgtcat caggccgagc gtaatcgtac cggcaacaat
     3481 tgacggaaac agcaagaaca aaccgaaaac gttatcgacc tgcaaataga gaatgcgggc
     3541 gatgttgaaa tacatatagt gaaaatagag gcggaaatag tttttccgca cggcgctaaa
     3601 cagctcgcgt accgtaggcg gcgtcgcacg cgtggcatcg tcttcaccat aaaccagctc
     3661 tttacggtag gcggcctcta ctcgctggtt tttaaactcc agccccggca gtttgatccc
     3721 taccactgcc agcaatccgg tccccatcag cgaccagacg atagcggcaa tcaccagacc
     3781 atacggaatg tgcccgataa tcggcagctc cggcacatgc gtggagagcg ttaccagcac
     3841 cggcaggaag gcgatcaacg tcatgatggc gttgataaaa ctgacgccca tattctccag
     3901 cgttgaagca aaacgcatgg tgtcttcctg cacacgctgt gcggcccctt cgatatgacg
     3961 cagttgttgc cagttcgcca tgtaatattc gttcatcgcc gtacgccagc ggaacacgta
     4021 gtgactgaca aagaagttgt tcagcacact gatcaccaca gcgatcagcg caatccccag
     4081 aaagacgccc acttcgcggt aaaattgttc gatagtgact ttatgcggcg aacttagcgc
     4141 ggtttgaatc agatcataga acggtgcata ccaggcgttg acggcgaccc cgacttccac
     4201 caaaaaccag gtgacgaaga tgatcagtgc agtaccgagt attgaccagt attgccaacg
     4261 gtgcgggctg tagataaacc agaaaaatgc aaaaagtcct acgcaaacaa tgtagtaagc
     4321 gtaaaaaatc aggaaatcca acgaccagaa acgcgcggcg ctaatcggga tctgcccgga
     4381 agcgccagtg atacgcgcca cccagtctcc cccaccggct tgccagaaga taacggcaat
     4441 caatgcccaa acaaaggccg agagaaaaaa cgctcccggc tttgggaaaa aagacttaaa
     4501 catatgcact cctgctaact tcttatcgtt ttaacaactg ctgtgtatta accgcatgac
     4561 cactacaaag cgtcagccaa atgaaaccgc ccattgtgac ccatagcaag gtgcttagtt
     4621 cgccagcctg accataagaa ttgtttcgac ggatttcaca aaccaaagat tgtttacata
     4681 agcggattaa cacgcgcagg atcacaaatg caggcattgg tgagcaggaa aaagatcgtg
     4741 tttacgcgcc gttacgtttt taacactatt attgcactaa ttcgcccttt gcaatccatc
     4801 aatgagtagt ataaatacgc tcagttacct tcattcaatt tatggacacc accgttgaaa
     4861 cgtagtctgc ttttttctgc cgtgctgtgt gcggcgtcat tgacctccgt ccatgcggcg
     4921 cagccgatca ctgaaccgga gtttgcctct gatattgtcg atcgttatgc cgatcatatt
     4981 ttttacggca gcggtgccac ggggatggcg ctggttgtta tcgacggtaa ccagcgcgtc
     5041 tttcgtagtt atggcgaaac gcgacctggt aataacgttc gcccgcagct ggattcggtc
     5101 gtgcgtattg cttccctcac caaactaatg accagtgaaa tgctggtgaa attgctcgac
     5161 caggggaccg taaagttaaa cgatccgcta agtaaatatg ctccgccagg cgcacgcgtg
     5221 ccgacctaca atgggacgcc cattacccta gtgaatctgg caacccatac cagcgccctg
     5281 ccccgtgaac agcccggtgg cgcggcacat cgtccggtgt ttgtctggcc aacgcgcgag
     5341 caacgctgga aatacctttc tacggcgaag ctgaaagccg cgccaggcag tcaggcggcg
     5401 tactctaacc ttgcgttcga cctgctggca gatgcactgg cgaatgcgtc cggcaagcct
     5461 tatacccagt tgtttgaaga gcagattacc cgtccattgg ggatgaaaga caccacctac
     5521 accccctcac cggatcagtg ccgccgttta atggttgctg agcgcggtgc cagtccgtgc
     5581 aataacacgc tggcggcaat tggcagcggc ggcgtctatt ccacgcctgg cgatatgatg
     5641 cgctggatgc agcagtattt gtcatctgat ttttatcagc gcagtaacca ggcagatcgc
     5701 atgcagacgt tgatttatcc gcgcgcgcag tttacgaaag tgattggcat ggatgtcccc
     5761 ggcaaagcgg atgcgcttgg tttaggctgg gtatatatgg ccccgaaaga gggtcgtccg
     5821 gggattattc agaagacagg cggtggtggc ggtttcatta cctatatggc gatgatcccg
     5881 cagaagaata ttggcgcgtt tgtggtggtc actcgttcgc cgttgacgcg ctttaaaaat
     5941 atgagcgatg gcatcaatga tctggtgacc gagctaagcg ggaataaacc gttggttatc
     6001 cccgcatcct gattaatact ctgaaggcaa acggttgata gcgaccagtt tgcctttatt
     6061 catttcgata tagccgcctt tacgcaaagc agcgagaact tctgcgacga cagaacgcga
     6121 tatgcgtgta cgttgatgga tataattcat cacaccaata cgtgatcgca attcttcatt
     6181 ccagtcaatc attgataata atgttgcgcg gatttgttcg taggaattat gcccaatgag
     6241 ctgcacgtcg cgtaattcca gaattctatt ttgccaggct aaccagtaaa aagcgtctcg
     6301 ccagagttga ttttgttcaa taagcgtaat ggtttgtttg gctggtagat gatatcccgt
     6361 acaatttcct tctgatatta atttgtatgg tatatcgttt ttcattaaac catcagccag
     6421 ccccataata taaggagcct gggtaatacc gataagtacg ttttcttctc tacgcagaga
     6481 gataacgccc tctaaaataa cgaaagtatc ttcgctattg acatcactgg aaaatataac
     6541 ttgcttttca ttattaaact cgaagcgcgt accgtatctg gacaaacatt tatcgagctt
     6601 accaaattcc tgaagaggtt taactacaga taacatttgc gcgtcctttg cagtaatgcc
     6661 cgtcaaatcc ttgacgggca ttatttagat taaattacca gaatttcttc ggagtgaaga
     6721 atattaccag gtatatttaa cacccacgtt cgcggaccaa tcttgatcta cgtcaccacc
     6781 accgaggtag ttagcatcgg tataggcgct gaagttcttg gtgaagctga actgagtacc
     6841 cagaccaaca cgtaccgcag acccttcagt accgttatcg atggaatcac cgttcacatc
     6901 gttatcgttg ttagagtcgt cgtagacgta agccagtttg aagtacggag tcagagcctg
     6961 gtcttcgctg taggtgaagg tataacctgc atctacaccc agttcataac gcatgctgtc
     7021 gtaagactga ccgtcaactt tcatgtcgtt gctcagctgg tagtcatcac cagactggaa
     7081 cagaccagaa atgctgccgt aaggagtcac ataaccagca tcacccagtt tgaagtcgta
     7141 accggctttc aagccgaagc cccaagcgtc ggagttggtg ctaccgtcaa cgtaagtacc
     7201 gttgctcatg gttgcagaca ggtcgttgtt gaagtgagag tagctcaagc taccatcaac
     7261 aaagacgttg ttcgcgaagt gagcagaaga gtagatgtag gcagtctggc tatcttgatc
     7321 tacctgacca gaacgatcat tcatgtcacc tttagcgaag cctgcagccg caccgacgat
     7381 ccacttagcg ttgttaccgt caattttggt atcaacaccg accatgatgc cgttaacatc
     7441 ctgatcatag ttgatggtgc cgttgtcgcc gttgaagtta ccaccgaagt agcttaccca
     7501 tgcgccgccg ttatcagcca ggccatgacg agagttggtc agacgagtac caacggtgtc
     7561 ttgttccagg ttccagatat tggtgttcgc agacgggatg ctcagcgcca tgttagcgta
     7621 gtcggtcagc tccatctgtt gcagaacaac ggtgttaccg cgctgttcag cctgataggt
     7681 gtatgcaccc aggtcagctt tgttagcagc agagaaggtc gcgttgctgt ttttgtcgtt
     7741 gacgtagatc agctcgttgc cgttgtagtc agcgatagaa ccagcaccag ttgcgttgtc
     7801 gatacgaact ttgtagttac cggttgcagc aacaacgtta tcaacagagc tgttatccag
     7861 ttcagtaccg ttgtctacgt cgccgttacc attgatagtc aggtgaccat cagagttcat
     7921 agcaacaata ccgtaaccgt agttagactt ggaagtatcc cacgtacggt cgttcaccag
     7981 atcagcgttc agaacgtaat cgctgctatg gatattgaac acaccggata ctacgttacc
     8041 gttatggtca gcgatgttgc cgctggtcag ttccagttta tcggtacgga aagcttcagt
     8101 atcgaactga tcaacgttca catccagcac accaccgtta gttacggtga tagtattggc
     8161 gtacaggtta gaatagttat tccaaccagt agattcggtt aaattaacag tactatagct
     8221 atcaactgtc aggtggtcag tagcaacttc accatcttca ccaatgttca gtgaagagcc
     8281 attagttaag ccaatagtat cagaaagtaa ggaagaattc gtaacattga cttcagagcc
     8341 attatttata gctaaagtat caatgtttga agcgttaacg gtattccatt cagaaccatt
     8401 attcagagtg acgttaaaca caccgctctg gaatacttga ttatcaatcg tacgacccca
     8461 ggcattatct tctgctacaa cgcctggata caggctatta cctgtaacat cataccagtc
     8521 agtcgataca gtagagtcaa cgtcaacatt cgctgatgta gttgctgaac ctacccattt
     8581 ggaaccatta tccagagtga tattcagttc atcaacatta agtgagtcgt cagcccagcc
     8641 accattggtg tccagtacgc catcggcatt actgtcatga ccatgcggat agaagtttgc
     8701 gttgaaagta cttgcgaaaa caacatcacc cagcagagta gaattgctga aataaacatt
     8761 gtttttcatg gagtaatttg aagccgcact atcactgaaa tacagagcta catcattagc
     8821 tccgccctta ccagagtaat cactaggttc cgcagagtta ccatagaaac cactgtcttc
     8881 cagagtagtt acagaacctg aagtcactgt ggaatcgata actgagatat tgttatccca
     8941 agtatgagat tcagtagtgt aagtattgtt tacggtatta ccctgagtca ggctgatacc
     9001 agcaacacgg gagttgttag aaatattgat gttactttcg acatcaagat tcactgccag
     9061 cccaagaccg acaccaccgt ttgcaaacaa accggcgtat tcttcacctt caccagctgg
     9121 ggtacggaag gtttcgttag tatatttggt aacgtcacca ttcagatatg aatcagtgaa
     9181 gtataaacct tcgtaatcgt catcaattgt agaattagca atatttaaag tgaatacatc
     9241 accatcatgc caattatcat caattacgcg atcagtaccg tattcagaga actgatatac
     9301 ataatgacca tcactgcttt cacccatagg cagcattgaa gtgattgaac catgaatcag
     9361 ggagttgctg atgttcaact ggtttgttgt tccatcagta aaatcatgat tcaggtaata
     9421 tgtagagata gccccgttaa cagtgtcacc attaaaggtg gtatcgaaat caccgtttgt
     9481 gttgttatag tagacaaagc cactataatt cacatagtta ccatctacag tacccggtaa
     9541 atccatattg ctccagtcaa gagcagtagt tggattgtcg taataagtcc aggtgttata
     9601 agtagttgca ttagcctgag aggtgatagc cagagtgcaa gccaatgcta attgtgatac
     9661 tacaagtttc tttttccagg agtgcatttg tcatccctcc tcagggacgt aataagttga
     9721 tccatcaatt atcaatgcat agaaaacata ttatgtttcg cgctaacgat tatgctgtgt
     9781 tacagacgaa tggttcaatt attctttccc ctaagtccga atgtggacat atataattta
     9841 tggagaaaaa cacgcatcga atttataaaa acaccatatt tcaatatgtt gcagatgatg
     9901 ttat
//
LOCUS       DAPHKZ010000151         9898 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.152, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000151 DAPHKZ010000000
VERSION     DAPHKZ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9898
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.152"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            232..753
                     /gene="fecI"
                     /locus_tag="RH288_004027"
     CDS             232..753
                     /gene="fecI"
                     /locus_tag="RH288_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FecI"
                     /protein_id="HDV4033031.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQD
                     TFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPE
                     ERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKA
                     VEHCLLFRLEYGL"
     gene            750..1703
                     /gene="fecR"
                     /locus_tag="RH288_004028"
     CDS             750..1703
                     /gene="fecR"
                     /locus_tag="RH288_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fec operon regulator FecR"
                     /protein_id="HDV4033032.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQ
                     DNQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGAGGGWQLWQSE
                     TGEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTA
                     KDALQRPFRVLTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNA
                     GESLQFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVA
                     GLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
     gene            1790..4114
                     /gene="fecA"
                     /locus_tag="RH288_004029"
     CDS             1790..4114
                     /gene="fecA"
                     /locus_tag="RH288_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate transport protein FecA"
                     /protein_id="HDV4033033.1"
                     /translation="MTPLRVFRKTTPLVNAIRLSLLPLAGLSFSAFAAQVNIAPGSLD
                     KALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSW
                     TLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRI
                     PGVSAPENNGTGSHDLAMNFGIRGLNPRLTSRSTVLMDGIPVPFAPYGQPQLSLAPVS
                     LGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPK
                     ETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLL
                     QYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQPDSQHKFNIQGF
                     YTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYVNESTHE
                     MRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQ
                     NNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVE
                     PEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQAR
                     YDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTF
                     NLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKN
                     IFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF"
     gene            4159..5061
                     /gene="fecB"
                     /locus_tag="RH288_004030"
     CDS             4159..5061
                     /gene="fecB"
                     /locus_tag="RH288_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein FecB"
                     /protein_id="HDV4033034.1"
                     /translation="MLAFIRFVFAGLLLVISHAFAATVQDEHGTFTLEKTPQRIVVLE
                     LSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDL
                     IIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQH
                     KERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGASMPS
                     IGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRG
                     IFAAERIAADTVKIFHHQPLTVVK"
     gene            5058..6056
                     /gene="fecC"
                     /locus_tag="RH288_004031"
     CDS             5058..6056
                     /gene="fecC"
                     /locus_tag="RH288_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate ABC transporter permease FecC"
                     /protein_id="HDV4033035.1"
                     /translation="MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALL
                     PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAA
                     LAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
                     AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQL
                     NLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAG
                     FDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
     gene            6053..7009
                     /gene="fecD"
                     /locus_tag="RH288_004032"
     CDS             6053..7009
                     /gene="fecD"
                     /locus_tag="RH288_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter permease
                     subunit FecD"
                     /protein_id="HDV4033036.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHY
                     YVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLL
                     MPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSR
                     PQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLG
                     VSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTG
                     ALLLVVADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR"
     gene            7010..7777
                     /gene="fecE"
                     /locus_tag="RH288_004033"
     CDS             7010..7777
                     /gene="fecE"
                     /locus_tag="RH288_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter ATP-binding
                     protein FecE"
                     /protein_id="HDV4033037.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTL
                     LNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRN
                     PWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVV
                     LLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMA
                     QGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
     gene            complement(8334..8591)
                     /locus_tag="RH288_004034"
     CDS             complement(8334..8591)
                     /locus_tag="RH288_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033038.1"
                     /translation="MTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFP
                     LAKKGEGRARLPSLYTSFGKLGETPTHEDIIDNNRSINWSV"
     gene            complement(8674..9871)
                     /locus_tag="RH288_004035"
     CDS             complement(join(8674..9589,9588..9871))
                     /locus_tag="RH288_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDV4033039.1"
                     /translation="MLTSEQHRCHNEKRNFSAEFKRESAQLVVDQKYTVADAASAIDV
                     GLSTMTRWVKQLRDERQGKTPKASPITPEQIEIRELRKKLQRIEMENEILKKGYRALD
                     VRLPEQFSIIGKLRAHYPVVTLCHVFGVHRSSYRYWKNRPEKPDGRRAVLRSQVLELH
                     GISHGSAGARSIATMATRRGYQMGRWLAGRLMKELGLVSCQQPTHRYKRGGHEHVAIP
                     NYLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFARKPVGWAMSFSPDSRLTM
                     KALEMAWETRGKPGGVMFHSDQGSHYTSRQFRQLLWRYQIRQSMSRRGNCWDNSPMEC
                     FFRSLKNEWMPVVGYVSFSEAAHAITDYIVGYYSALRPHEYNGGLPPNESENRYWKNS
                     NAEASFS"
BASE COUNT         2132 a         2817 c         2711 g         2238 t
ORIGIN      
        1 ccccatcctt tagggcagtg aggatgtcaa taatagcaga ccacatcatg agtcattctg
       61 accgacacat gccagaagca gaggctccat cccattttat acctacctta taacacttag
      121 aaaaacaaca tgttaaaaat gtctattgga aacaatttta tttccaattg taatgataac
      181 cattctcata ttaatatgac tacgtgataa ttaacttttg atgcactccg catgtctgac
      241 cgcgccacta ccacagcttc cttaacgttc gagtcgcttt atggcacaca tcacggctgg
      301 ttgaaaagct ggctgacgcg caaactccag tctgcttttg atgcagatga cattgcccag
      361 gacacttttt tgcgggtaat ggtcagcgaa acgctctcga cgatccgcga tcctcgctcc
      421 ttcctctgca ctatcgccaa acgcgtgatg gtggacctgt ttcgccgaaa cgcgctggaa
      481 aaagcgtatc tggagatgct ggcgcttatg ccggaggggg gagcgccttc acctgaggaa
      541 cgcgaaagcc aactcgagac cctacaactc ctcgacagca tgctggacgg gctaaacggc
      601 aaaacacgtg aagcgtttct gctttcgcaa ctggatggtc tgacatacag cgagattgcg
      661 cacaaactcg gtgtttccat cagctccgtg aaaaaatacg tggcgaaagc cgtcgagcac
      721 tgcctgctgt tccgtctgga gtatgggtta tgaatccttt gttaaccgat tcccgccgtc
      781 aggcgctgcg ttcagcttcc cactggtatg ccgtgctaag cggcgagcgc gtcagcccac
      841 aacaggaagc gcgctggcaa cagtggtatg aacaggatca ggataaccag tgggcctggc
      901 agcaggttga aaacctgcgc aaccagcttg gcggtgtgcc tggcgacgtt gccagccggg
      961 cgttgcacga tacccgcctc acccgccgtc acgtgatgaa aggattactg ctgttgctcg
     1021 gcgctggcgg aggctggcag ctctggcagt cggaaaccgg cgaaggtctg cgggcagatt
     1081 accgcaccgc caaaggcaca gtcagccgtc agcaactgga agatggctcc ctgctcacgc
     1141 tgaataccca aagcgcggcg gatgtgcgtt ttgatgcgca tcagcgcacc gtccggctct
     1201 ggtacggtga aatcgccatt actaccgcga aagatgccct gcaacgcccc ttccgtgtcc
     1261 tgacccgtca gggccagctc actgctttag ggacagaatt taccgtccgc cagcaggata
     1321 atttcacgca gcttgacgtt cagcagcacg ctgtggaagt gcttctcgcc agtgcccccg
     1381 cgcaaaaacg catcgtgaac gctggtgaaa gcctgcagtt cagcgcctct gagtttggcg
     1441 cagtgaaacc gctggatgac gagagtacaa gctggacgaa ggacatcctg agcttcagcg
     1501 ataaaccact gggtgaggtg atagccacgc taacccgtta ccgcaacggc gtgctgcgct
     1561 gcgatcccgc cgttgccggg ctgcgcctga gcgggacgtt cccgctgaaa aataccgatg
     1621 cgatcctgaa cgttatcgcg caaacgcttc ccgttaaaat tcagtctatt acgcggtact
     1681 ggataaacat ttcaccactg taaggaaaat aattcttatt tcgattgtcc tttttaccct
     1741 tctcgttcga ctcatagctg aacacaacaa aaatgatgat ggggaaggta tgacgccgtt
     1801 acgcgttttt cgtaaaacaa cacctttggt taacgccatt cgcctgagcc tgctgccgct
     1861 ggccggtctc tcgttttccg cttttgctgc acaggttaat atcgcaccgg gatcgctcga
     1921 taaagcgctc aatcagtatg ccgcacacag cggatttacc ctctcggttg acgccagcct
     1981 gacgcgcggc aagcagagca acggcctgca cggcgattac gacgtcgaga gcggcctgca
     2041 acaactgctg gacggcagcg gactgcaggt aaaaccgctg ggaaataata gctggacgct
     2101 ggagcccgcg cccgcaccaa aagaagatgc cctgaccgtg gtcggcgact ggctgggtga
     2161 tgcgcgtgaa aacgacgtat ttgaacatgc tggcgcgcgt gacgtgatcc gccgtgagga
     2221 tttcgccaaa accggcgcaa ccaccatgcg tgaggtactt aaccgcatcc ctggcgtcag
     2281 cgcgccggaa aacaacggca ccggcagcca cgacctggcg atgaactttg gcatccgggg
     2341 cctgaacccg cgcctcacca gccgctcgac cgtcctgatg gacggcatcc ccgtcccctt
     2401 cgccccttac ggtcagccgc agctttcact ggctcccgtt tcgctcggca acatggatgc
     2461 cattgacgtg gtacgcggtg gtggtgcggt gcgttacgga ccgcagagcg tgggcggcgt
     2521 ggtgaacttt gttacccgtg ccattccgca ggactttggt atcgaggcgg gcgtggaagg
     2581 tcagctcagc ccaacctctt cacaaaacaa cccgaaagag acgcacaacc tgatggtggg
     2641 cggcacagcg gacaacggtt ttggcaccgc gctgctctac tccggcacgc gcggcagtga
     2701 ctggcgcgag cacagcgcca cccgcatcga cgacctgatg ctgaaaagca aatatgcgcc
     2761 ggatgaggtg cacaccttca acagcctgct gcaatattac gacggtgaag ccgacatgcc
     2821 cggtggcctg tctcgcgcgg attacgacgc cgatcgctgg caatccaccc gcccgtatga
     2881 ccgcttctgg ggtcgtcgca agctggcgag cctgggctac cagttccagc cagacagcca
     2941 gcataaattc aacattcagg ggttctacac ccaaaccctg cgcagcggct acctggagca
     3001 aggcaaacgc atcaccctct cgccgcgtaa ctactgggtg cgcggtattg agccacgcta
     3061 cagccagatc tttatgatcg gcccttccgc gcacgaagtg ggcgtgggct atcgctatgt
     3121 gaatgaatca acgcatgaaa tgcgttacta caccgccacc agcagcgggc agttgccgtc
     3181 cggctcaagc ccttacgacc gcgatacgcg ttccggcacc gaggcgcacg cctggtatct
     3241 ggatgacaaa atcgacatcg gcaactggac catcacgccg ggtatgcgtt tcgaacatat
     3301 cgagtcatac cagaacaacg ccatcacagg cacgcacgaa gaagtgagct ataacgcacc
     3361 gcttccggcg ttgaacgtgc tctatcacct gactgacagc tggaatcttt atgcaaacac
     3421 tgaaggctcg ttcggcaccg tacagtacag ccagattggc aaggctgtgc aaagcggcaa
     3481 tgtggaaccg gaaaaagcgc gaacctggga actcggtacc cgctacgacg acggcgcgct
     3541 gacggcggaa atggggctgt tcctgattaa ctttaacaat cagtacgact ccaaccagac
     3601 caacgacacc gtcactgcac gtggcaaaac gcgccatacc gggctggaaa cgcaggcacg
     3661 ttacgatctg ggtacgctaa cgccaacgct tgataacgtt tccatctacg ccagctatgc
     3721 gtatgtgaac gcggaaatcc gcgagaaagg cgacacctac ggcaatctgg taccattctc
     3781 cccgaaacat aaaggcacgc tgggcgtgga ctacaagcca ggaaactgga cgttcaatct
     3841 gaacagcgat ttccagtcca gccagtttgc ggataacgcc aatacggtga aagagagcgc
     3901 cgacggcagt accggccgca ttcccggctt catgctctgg ggcgcacgcg tggcgtatga
     3961 ctttggcccg cagatggcag atctgaacct ggcattcggt gtgaaaaaca tcttcgacca
     4021 ggactacttc atccgctctt atgacgacaa caacaaaggc atctatgcag gccagccgcg
     4081 cacgctgtat atgcaggggt cgttgaagtt ctgatgtgtt aacgcccggc ttgccgggct
     4141 tttagctgga atgtgattat gttggcattt atccgttttg tttttgcagg cctgctgctg
     4201 gtgatcagcc acgcctttgc cgccacggtt caggacgaac acggcacgtt tacactcgaa
     4261 aaaacgccac aacggattgt ggtgctggaa ctctcgttcg ccgatgcgct ggccgccgtg
     4321 gacgtcagcc cgatcggtat tgccgacgat aacgatgcaa aacgcatcct gcccgaagtg
     4381 cgtgcgcacc tgaaaccgtg gcagtccgtc ggaacgcgcg cgcagccgag cctggaagcc
     4441 attgccgctc tgaaaccaga cctgatcatt gccgacagca gtcgccatgc gggggtttac
     4501 atcgccttgc agcaaatcgc gccggtactg ctgcttaagt cccgcaacga aacctacgct
     4561 gaaaatttgc aatctgcggc tatcatcggc gaaatggtgg gtaaaaagcg agagatgcag
     4621 gcacgcctgg aacaacataa agagaggatg gcgcagtggg ccagccagct tcccaaaggg
     4681 acacgcgtgg cctttggcac atcacgcgaa cagcaattca acctgcatac tcaggagacc
     4741 tggaccggca gcgtgctggc ctctctgggg ctgaacgttc ccgctgcgat ggcgggtgcg
     4801 tccatgccgt ccatcggcct ggagcaactg ctggcggtca atcctgcctg gctgctggtt
     4861 gcccactatc gcgaagagag cattgttaaa cgctggcaac aagatccgct ctggcagatg
     4921 ttaaccgccg cgcagaagca gcaggttgct tcggtcgaca gtaacacctg ggcgcggatg
     4981 cgcggtattt ttgctgcaga gcgtattgcc gctgacacgg taaaaatctt ccaccatcag
     5041 ccgcttaccg ttgtgaaatg accgcgataa aacacccggt gctgctgtgg gggcttcccg
     5101 ttgcagcact tattattatt ttctggctga gtctgttttg ctactcggcc attcctgttt
     5161 ccggagcaga tgcaacccgc gccctgctgc ctggacacac gccaacgcta ccagaagcgc
     5221 tggtgcaaaa ccttcgtttg ccacgaagcc tggtcgccgt tctgatcggc gcaagcctgg
     5281 cgctcgcggg cacgctgctg caaaccctga cccacaaccc aatggcctct ccttcactgc
     5341 tcggcattaa cagcggcgcg gcgctggcta tggcgcttac cagcgcgctg agtccgacgc
     5401 cgattgcagg ctattctctg tcgttcatcg cggcatgcgg gggcggcgtg agctggctgc
     5461 tggtcatgac cgcaggaggc ggatttcgtc atacccatga cagaaacaaa ctgatcctcg
     5521 cgggtatcgc gctgtcggcc ttttgtatgg gccttacccg catcaccctg ctgctggccg
     5581 aagatcatgc ttacggcatc ttttactggc tggcaggcgg agtgtcccac gcccgctggc
     5641 aggatgtctg gcagctcttg ccggtggtgg tcactgcagt ccctgtcgtg ttgctgctgg
     5701 cgaatcaact gaacctgctc aacctcagcg acagcaccgc ccatacgctg ggagtgaacc
     5761 tgacgaggct acgtttggtc atcaatatgt tagtgctgct tctggttggt gcgtgcgtca
     5821 gcgtggcagg tccggtggcg tttatcggtc tgctggtgcc acatctggcg cgcttctggg
     5881 caggcttcga tcagcgcaac gtactgccag tgagcatgct gctgggggcc acgctgatgc
     5941 tgctggcaga tgtactcgca cgcgcactgg ccttccccgg agatctgccc gcaggcgcag
     6001 tgctggcgct gattggcagc ccttgctttg tctggcttgt gaggaggcga ggatgaaaat
     6061 tgcgctggtt attttcatca cccttgccct ggcgggctgt gcgctgttat cactccatat
     6121 gggagtgatc cccgtgccgt ggcgcgcgct gctgaccgac tggcaggccg gacgcgagca
     6181 ttattatgta ttgatggagt accgactgcc gcgcttgctg ctggcactgt ttgtcggtgc
     6241 agccctcgcc gtggcgggcg tgctgataca ggggattgtg cgcaaccctc tggcatcacc
     6301 ggatattctc ggcgttaacc atgccgccag cctggcctct gtgggggctc tacttcttat
     6361 gccgtcactg cccgtgatgg tgctgccgct gctggccttt gcgggcggca tggcggggtt
     6421 gatattgctg aagatgctgg caaagaccca ccagccgatg aagctggcgc tcaccggcgt
     6481 ggcgctttct gcatgctggg ccagcctgac ggattatctg atgctctcgc gcccgcagga
     6541 tgtgaacaac gccctgctgt ggctgaccgg cagcttatgg ggccgtgact ggagctttgt
     6601 gaagattgcc atcccgctga tgattttatt tctgccgctg agcctgagtt tttgccgcga
     6661 tctcgacctc cttgcactcg gcgatgcgcg cgccaccacg ctcggtgtgt cggtgcccca
     6721 tacccgattc tgggctttgt tactagctgt cgccatgaca tctaccggcg tggccgcctg
     6781 cggcccgatt agctttattg gtctcgtggt gccgcatatg atgcgtagca tcaccggtgg
     6841 acgtcaccgc agactgctgc ctgtttcagc cctgacaggt gcgttgctgt tggtggttgc
     6901 cgatctgctg gcgagaatta ttcatccccc actggagctc ccggttggcg tgctgaccgc
     6961 cattatcggt gcgccgtggt ttgtctggtt gcttgtgaga atgcgataaa tgactttacg
     7021 aactgaaaat ctgacggtca gttacgggac agacaaggta cttaacgacg tttcactctc
     7081 actgccaacg gggaagatca ccgccctgat cggtcctaac ggttgcggga aatcgacgct
     7141 gttaaactgt ttttcgcggc ttttaatgcc gcagtctggc accgtatttc tcggcgataa
     7201 tcccataaat atgctctcat cgcgccagtt ggcccgcagg ctttcgctgc tgcctcagca
     7261 ccatttaacg ccagagggga tcacagtcca ggagctggtt tcgtatggtc gtaatccctg
     7321 gctgtcactc tgggggcgtc tctccgctga agacaatgca cgagttaatg tcgccatgaa
     7381 ccagacccgg atcaatcatc ttgccgttcg tcggttaacc gagctttccg gcggtcagcg
     7441 ccagcgcgca tttctggcaa tggtcctggc ccagaatacg cccgttgtat tacttgatga
     7501 gccaaccacc tatcttgata tcaatcacca ggtggacctg atgcggttga tgggcgaact
     7561 ccggactcag gggaaaacgg tggtcgctgt gctgcacgac cttaatcagg ctagccggta
     7621 ctgcgatcaa ctggtggtaa tggcaaacgg acatgttatg gcgcaaggca caccagaaga
     7681 ggtgatgacc ccaggattgc tgagaacagt attcagcgtg gaagcggaaa tacaccccga
     7741 gccggtatct ggcaggccga tgtgcctaat gaggtagatt gcacaggccg taagaaccaa
     7801 accacgactg aatgaaactg gactggcgcc agcaagcctg ttcagactgg ggctgaactt
     7861 ttccggactc tgaaagatta ccaatactca tcgtccatcc gcttgcttta ggctgacagg
     7921 ttcataatca acgcaaacca gagctgtaca ggcttgggcg cggctttcaa accagtcgtg
     7981 atcacggcaa tcaattttga actctgctta acggacattt ctgtataacc cttacggcaa
     8041 cgaaaaacgc gaagttaaaa ttttagaaac ccaaaaacgt gacatgacta agtttagatt
     8101 tcagggggga gatcaaaaaa tttcgctctg tgccagagcg gacattcacg gagctggttc
     8161 attaccaatg aggttgggct tttgaggata aatcaatgat cagacgccaa cgtaaatcaa
     8221 aagcaaccct ggaacggaat tgctaatcca gtttctgacc atcgattttt ctaaaaagtg
     8281 tgcgtttgct actacttagg taggtgcagc tttcttaatc accggcagcc acgttataca
     8341 gaccagttga tggatcgatt gttatcaatg atatcttcat gagtcggtgt ctcacccagc
     8401 ttaccgaagc tggtataaag tgaaggcaga cgggcccgtc cttctccctt tttcgccaga
     8461 gggaaagcgc gaagcatggt ggcagcctcc cagtcacaac aataggatgg tgtgcacggc
     8521 tgctgacgcc atgattcagc gatagagccg gaaaatacgg ggtcaaagcc ggtatcatta
     8581 accagagtca tcgtgacctg tactgcggct ggatgatctc ctgctactgc aactgccagg
     8641 cgaccgcggc tcccttcagg tagtctgttg tggtcaacta aaactggcct ccgcgttaga
     8701 gtttttccag tatcggtttt ctgattcgtt tggtggtaac ccaccgttat attcgtgcgg
     8761 tcttagtgcg ctgtaatatc caacgatata gtccgttatt gcgtgagctg cctcgctgaa
     8821 gcttacgtaa cccaccaccg gcatccattc gttcttcaga ctcctgaaga agcattccat
     8881 tgggctgtta tcccagcagt ttccgcgccg gctcatactc tgtctgatct ggtatcgcca
     8941 caataactgc cggaactgcc tgctcgtata atgactgccc tgatcgctgt ggaacatcac
     9001 cccgccgggc ttaccacggg tttcccatgc catttccagc gctttcatgg taagcctgct
     9061 gtccggcgag aacgacatgg cccagcccac tggttttctt gcgaacaggt cgagaacaac
     9121 ggcgaggtac gcccagcgct tacccgtcca gatataggtc acatcaccgc accacacctg
     9181 atttggctcg gtcacggcga actgcctttc aaggtagtta gggatagcaa catgttcatg
     9241 accaccacgt ttataccggt gagtcggctg ctgacagctg accagcccca gctctttcat
     9301 gagcctgcca gcaagccagc gtcccatctg gtagcctctc cgggttgcca ttgtggcgat
     9361 gcttcttgct ccggccgaac cgtggctgat gccatgtagc tcaagtacct gactgcgtaa
     9421 tacagcccgt ctgccgtctg gtttttcagg acggtttttc cagtatctgt agctgctgcg
     9481 atgaaccccg aacacatggc agagtgtgac cacaggataa tgcgctctga gtttcccgat
     9541 tatcgaaaac tgttcaggga gtctgacatc aagagcgcgg tagccttttt aatatttcat
     9601 tctccatttc aatgcgttgt agctttttcc ttagctcacg gatttcaatt tgttccgggg
     9661 taatggggga ggcttttggt gtttttccct gccgctcatc acgtaattgt ttcacccatc
     9721 gcgtcattgt ggaaaggccg acatctatag cgctggctgc atctgccacg gtgtatttct
     9781 ggtcaacgac cagttgagcg gattcgcgtt taaactctgc gctgaaattt cttttttcat
     9841 tatggcacct gtgttgttct gaggtgagca tatcacctct gttcaggtag ctaaattt
//
LOCUS       DAPHKZ010000152         9730 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.153, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000152 DAPHKZ010000000
VERSION     DAPHKZ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9730
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.153"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(222..980)
                     /locus_tag="RH288_004036"
     CDS             complement(222..980)
                     /locus_tag="RH288_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDV4033040.1"
                     /translation="MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLC
                     GPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPH
                     LTVLQNCTLAPIWVRKMPKKEAEDLAVHYLERVRIAEHAHKFPGQISGGQQQRVAIAR
                     SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVI
                     FMDRGEIVEQAAPDEFFAHPKSERTRAFLSQVIH"
     gene            complement(988..2091)
                     /locus_tag="RH288_004037"
     CDS             complement(988..2091)
                     /locus_tag="RH288_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDV4033041.1"
                     /translation="MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWL
                     MWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINL
                     ALLIGLVSIAPMFWKILPHRGRYIAAWAVIYPLIVWWLMYGGFFALERVETRQWGGLT
                     LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVML
                     PLFMAEGTSIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQ
                     GLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEG
                     YVFAALIYWIFCFSMSRYSQYLEKRFNTGRTPH"
     gene            complement(2101..3282)
                     /locus_tag="RH288_004038"
     CDS             complement(2101..3282)
                     /locus_tag="RH288_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDV4033042.1"
                     /translation="MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTV
                     TNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFA
                     SVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
                     FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWP
                     IAAVLIIGLPLLAQWLFGAALHWDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFI
                     AEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSS
                     LAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVE
                     R"
     gene            complement(3350..4375)
                     /locus_tag="RH288_004039"
     CDS             complement(3350..4375)
                     /locus_tag="RH288_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV4033043.1"
                     /translation="MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDG
                     LPGFSYADADGKFSGIDVDICRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLS
                     RNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
                     VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVL
                     PEVISKEPLGPVVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAH
                     LLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGI
                     QYAPPVR"
     gene            complement(4806..5027)
                     /locus_tag="RH288_004040"
     CDS             complement(4806..5027)
                     /locus_tag="RH288_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033044.1"
                     /translation="MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
     gene            complement(5280..8384)
                     /gene="acrF"
                     /locus_tag="RH288_004041"
     CDS             complement(5280..8384)
                     /gene="acrF"
                     /locus_tag="RH288_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
                     /protein_id="HDV4033045.1"
                     /translation="MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVS
                     VSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDI
                     AQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPDTTQDDISDYVAS
                     NVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ
                     LGGTPALPGQQLNASIIAQTRLKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN
                     VIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ
                     LSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK
                     GGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEE
                     DQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAG
                     MAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFE
                     LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGV
                     SLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMV
                     PFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGY
                     DWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLA
                     ATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLR
                     PILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR
                     CFKG"
     gene            complement(8396..9553)
                     /gene="acrE"
                     /locus_tag="RH288_004042"
     CDS             complement(8396..9553)
                     /gene="acrE"
                     /locus_tag="RH288_004042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrE"
                     /protein_id="HDV4033046.1"
                     /translation="MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIV
                     KTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQA
                     NYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
                     ATVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQS
                     SNDFMRLKQSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLR
                     AVFPNPQHTLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDATVLIVNDKSQVEAR
                     PVVASQAIGDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK"
BASE COUNT         2591 a         2523 c         2326 g         2290 t
ORIGIN      
        1 aacaaaaggc tcagtcggaa gactgggcct tttgttttat ctgttgtttg tcggtgaaca
       61 ctctcccgag taggacaaat ccgccgggag cggatttgaa cgttgcgaag caacggcccg
      121 gagggtggcg ggcaggacgc ccgccataaa ctgccagaca tcaaatcaag cgaaaggcca
      181 tccgaaagga tggccttttt gcttttcgaa ctaacattca attaatggat tacctgcgat
      241 aaaaatgccc tcgtacgctc tgatttagga tgcgcaaaaa attcatcagg tgcagcttgc
      301 tccactattt ccccacgatc cataaaaatt acccggtcag cgacggttcg tgcaaacccc
      361 atctcatgtg ttacacacaa cattgtcata cccgactgcg ccagcccaat catcgtatcc
      421 agcacctctt tcaccatctc aggatcgagc gccgacgttg gctcatcaaa caacataatt
      481 ttcggcttca tacacagcga acgcgcaatg gcaacgcgtt gctgctgacc acctgaaatc
      541 tgtccgggaa acttatgcgc atgttcggca attctcaccc gctctaggta atgcaccgcc
      601 agatcttcag cctctttctt aggcatcttg cgtacccaaa tcggtgccag ggtacagttc
      661 tgtaaaacgg tcagatgagg gaagagattg aaatgctgaa agaccattcc cacttcctgc
      721 ctgacgcgct caatattgcg gatatcttca ttaagttcga tgccatctac cacgatccgt
      781 ccctgttgat gttcttccag atgattaata caacgaatgg ttgtcgattt accggaacct
      841 gaagggccac acagaacgat ccgttctccc ggttgcacgg ttaaatttat atttttcaaa
      901 acatggaatt gtccatacca tttattgacg ttttccagcg taatcatcgc gttagcaggt
      961 tgcagtaaaa tttggctcat agtgtcctca atgcggtgta cgcccggtgt taaaacgttt
     1021 ttccagatac tggctatagc gcgacatgct gaaacagaag atccagtaga tcagcgcggc
     1081 gaaaacatac ccttccgtcg acatacccaa ccaggcggga tcaacggttg cctgctgaac
     1141 gctactgaaa agatcgaaca acccgataat gatcaccagg ctggtatctt tgaagagtgc
     1201 gatgatggta tttaccagcc caggaattac cagcttcaac gcctgtggca gaataaccag
     1261 cccctgagtt ttccagtaac ccaacgccag cgactctgcc gcttcatatt gccctttagg
     1321 cagcgcctgt aatccacctc gcacgacttc cgcaacatat gctgactgaa acaggatcac
     1381 gccaaccagc gcgcggatca atttgtcgat actggtgcct tctgccataa acaacggcag
     1441 catgaccgaa gacataaaca gaacggtaat cagcggcacg ccgcgccaga attcgataaa
     1501 aatgaccgat aagatacgca caatcggcat atgggagcgg cgacctaacg ccagtaagat
     1561 cccccacggt agcgcccccg caatcccaac tgatgcaata attaaagtta gcgtcagccc
     1621 gccccattgc cgggtttcaa cccgctcaag agcaaaaaaa ccgccataca tcagccacca
     1681 gacaatcagt gggtaaatca ccgcccaggc cgcaatatag cgaccgcgat gcgggagtat
     1741 tttccagaac attggtgcga tcgacacaag cccaatcagt aatgcgaggt taattcgcca
     1801 gcgttggtcg tgtgggtaaa gcccatacat aaactgacca aatcgttcgt ggatgaagac
     1861 ccaacaggca ccggcttttg tgcagtcggc acgcgttgag ccaacccagt tagcctgcaa
     1921 aaatgcccag ttcagcaacg gtgggatcag ttcccacatc aaccatatgc agccaatagt
     1981 cagcaggcta ttgctccagc tggagaacag attttttcgc acccacacca tcgcgcggct
     2041 tgagttatgg ctcgccgggc gcgggggatg agacagcaat acttttgtca tcatgactcc
     2101 ttagcgttca acgatcgcga tgcggcggtt atagatattc atcagcagcg agatagtcag
     2161 gctgataatc agatagaccg acatggtcat ggctatcgtc tcgatggctt gccccgtctg
     2221 attcagcacg gtgccggcaa acagcgaaac catatcggga tagccaatag cggcggcaag
     2281 agaggagttt ttgacgatgt tgagatactg gctggttaac ggtggaataa tcacccgcaa
     2341 tgcctgggga ataatgacct ggcgtagcgt aaccgggttg ggtaatccca gtgaccgagc
     2401 cgcttcatgt tgaccataag gcactgcctg gatcccagcg cggataatct cggcgataaa
     2461 tgcagatgta taaaccgaaa gtgccagcgt taaggctgcc agttcaggaa ttaaaaccat
     2521 cccgccgcgg aagttaaagc ctcgtagggc tgggacatcc cagtgtagtg ctgcgccaaa
     2581 aagccattgc gccagtaaag gcaaaccaat gatcaacact gcggcgatcg gccaggtgcg
     2641 gcgcagttgt ccggtcttta tctggtatgt tttattaaag cggaatagcc caacagaaag
     2701 gactatagcc ataacaacag ccaggataaa cgcaataaat ccgtctccca gctgcggtga
     2761 cggaatataa agcccacgat tgctcaaaaa ggccagatca aacgcgctca cagcctggcg
     2821 tggtccgggc aaattgcgca acacggcaaa gtaccagaag aagatttgca gcagcggggg
     2881 aatattacgg aagatctcaa tataaattgt ggaaagcttt cgtagcagcc agttatccga
     2941 aagtctcgcc agaccgataa agaagcccaa aacagaagcg aacacaatac acaatgcaga
     3001 aaccagtagc gtattgagta agccgacaat aaaaacgcgt ccgtaggtgt cgccctgctg
     3061 gtaatcgatc aaatgctgga caataccgaa gccagcgccg cgatccagaa aggcaaaacc
     3121 tgaagtaatg ccacgattat tgagattcgt tacagtgttg tgaaataacc aaccaacaat
     3181 gccgacaaca gcaacaacgg caaggatctg gaataaccag gcgcgaaccg tagggttggc
     3241 aaaagagagt gagcctttaa cggttgagcg gcgatgagac atagaaacct cggaaagcat
     3301 aacgctgaag agagcgccgc cgtagcgacg ctcgttacct cacaccgact taacgcacgg
     3361 gcggtgcgta ctgaataccg ccgttattcc agagattatt ttgcccacgt ttaattttca
     3421 gcgggctttc tgaacctacg ttacgctcaa aaatttccga gtagttaccc acctgtttga
     3481 tgatgttata ggcccattta ttatccaact tcagatcctt gccgtaatcg ccttctttac
     3541 ccagcagatg tgccatatca ggcgttgctg gattagccgc tttttcatcg acgttctggg
     3601 aattgatgcc catctcttca gcatttagca tggcgaaaag cgtccagcgt acaatcgaga
     3661 accattcatc atcgccacga cgaactaccg gcccaagcgg ttctttagag ataacctccg
     3721 gtaagacaat ccattcagcc gggttgctta atttgatgcg cagggcatac agttgggatt
     3781 gatccgaagc cagcgtatcg cagcgaccag attccagtgc cttcgctgat tcgtcagagc
     3841 gatcgaaagt cactggtgtg tacttcatat tgtttgcctt gaaatagtcg gcgacgttga
     3901 gttcggtatc agtacccgcc tgaatacaga cggtagcgcc atccagttct ttcgcgcttt
     3961 ttagccccgc tttatcgtgc gtcaggaagc caatgccgtc gtaataagtg acgccagtaa
     4021 atgccattcc catcccggca tcgcgagatg aagtccaggt cgtattacgg gagagcaaat
     4081 ccacctcccc tgactgtaaa gcggtgaagc gttcttttgc agtgagcggg gtatatttca
     4141 ctttcgtgtc gtcaccaaat acagcagcgg caacaccacg acaaatatca acatcaatac
     4201 ctgaaaattt accgtcagca tcggcataag agaacccagg taatccatca ctgatcccgc
     4261 attgcacaaa accttttttc tgtacggcat caagcgtcgc gccagcgtgc gcctgatttg
     4321 caacggcaag cagcacgctg gcggcagcca gtgtggctat catcatcttt ttcataatgc
     4381 ttcctgtgag gcgaaaatta tcgttatagg acgtttggga aacgtctttt acctgtctgt
     4441 ggccatcctc ttataagcaa aagtagtgcc agcttttgcg cacgatttcg cgtcgcaata
     4501 agctgagtgt agacaggaaa taataaaaac agcgccccgc aatggtgcga aaatgaaaca
     4561 tgcgccacat tttggcgcaa aatatttacg cgtgttttac taagcagaat aatgattgtt
     4621 agcgtgagta tatttctggt gggaagtgcg aaagttaaat tgatgcgtta tttcgaaagc
     4681 agcgaaataa cgcgatataa catgctaagt cagcagagaa ttagccagca gaatatagca
     4741 atattttatc ttatgtaaag atactgtatc gttaaacaga gcgcgaaact ccgcgccctg
     4801 ttcagttatt tcgacagagc gatgatcccc atcgtcaggc cagcaacagc tgctgctccg
     4861 ccagcaatag ccccagccgt ttcccagtta tcctgagttg tgcctttcat acaggtattg
     4921 gtgtgaacca gacgcccctg atcgtcataa accggaacgc agggcgaatc gtgagcacag
     4981 cccgccagca atgcggtgag caatgccaca ggaattaatc ttttcatggt gttacctcag
     5041 taataaacgc taacgcttaa taagttaact ctcttattaa cgagctgaat gccattttat
     5101 caccggaggt tataaatctt gcggaatgaa taatgacaaa ttatgtgaat tgtaaaaata
     5161 gtgaagggag cgggaactat agaaagcttt taaagagtga gcaaaagaat atcttattaa
     5221 tttttatggg tttcactgaa aataataaag gcacccgaaa gcgcctttat gtttcagatt
     5281 tatcctttaa agcaacggcg gatcaccaca aagaacaccg gtacgaagaa gattgccagc
     5341 aacgttgcag agaccattcc gcccattacc ccgataccca ctgcgttctg cgcgccactg
     5401 ccggcaccgt tactgatagc tagcggtaat acgccgagaa taaaggcgag agaggtcatc
     5461 aggataggac gcagacgcat acgtactgcc attagtgtcg cttcaacaac acctttaccc
     5521 tctttctcca tgagatcttt agcgaactca acaatcaaaa tagcgttttt ggccgacaag
     5581 ccaattgtcg ttagcaagcc caccataaag tagacgtcat ttttttgatt aaagagtgtt
     5641 gccgccagta gcacgccgac aatccctaac ggcactacca acataaccga gacaggaatt
     5701 gaccagcttt catagagtgc agcaaggcac aggaaaacaa ccacaaagga aattgctacc
     5761 agagcgggag cctggtttcc cgataagcgt tcctgatacg acatacccgt ccagtcataa
     5821 ccaatgcccg caggtaattt tgacgcaagg ttttccatca acgccatggc atcgccggaa
     5881 ctggttcctg gcgcggcttc cccctgaatc tccattgacg gcagaccgtt gtagcgttcc
     5941 agtcgcggag agccatacac ccaatgtgaa gtggtaaagg ccgagaatgg caccatttcg
     6001 ccgttggcgc tgcggacata aagtttatcg acatcttctg gcagcatacg gaatttggca
     6061 tccgcctgaa catacacctt tttcacacga ccacggtcga tgaagtcgtt aacgtaagtc
     6121 ccacccagcg ccgttgaaat ggtctgattg atgtcagaaa gtgaaacacc taatgcctgc
     6181 gccttttcct ggtcaacttc cagtttaaac tgcgcggtgt cttccaggcc attaggacgc
     6241 acgctgacta agctggcagg atgttgcgca gccataccaa gcaactggtt acgggcctgg
     6301 gttagggcat cgtgacccag cccagcctga tcaattaact caaagtcgaa acccgttgcc
     6361 gtgcccagtt caacaatggc tggcatattg aatggaatga caaaaccgtc gcggatcttg
     6421 cccaattcca ttttggcacg atggattacc gcttccgcac tgttttcatc accattacgc
     6481 tcttcccacg gtttcagact gacgaaggcc ataccggcgt tttgtgcctg gccgctgaag
     6541 ctaaagccgt taaccgtaaa gacactttca acgttcgctt tctcgttctt cagatagtaa
     6601 tccgtcactt gatccaacac tttttgcgtc cgctcttgcg tcgcgccagc gggtaactga
     6661 atcatggtca gaaagacacc ctgatcctct tcaggtaaga aggaagacgg aagacgtaaa
     6721 aacaacacca ccattcctgc aacaatcagc gcatagatca gtaaatatcg tcctgtggaa
     6781 ccgaggattt tgccgacgct gttggtgtag tggttaacgc tatgatcgaa ggtggtatta
     6841 aaccagccga agaaaccgcc cttattttcg tgatgctcag cagagacggg tttaagcagc
     6901 gttgcacata acgcaggggt aagaatcaat gccaccagaa cagaaagcgc cattgccgaa
     6961 acgatggtga tagagaactg gcgataaatt gccccagtag aaccgccgaa gaatgccatc
     7021 ggaataaata ccgctgacag caccatcgcg atacccacca gtgcgccctg aatttgcgac
     7081 attgattttt ccgtcgcttc ttttggcggg agcttatcct ccatcatcac gcgctcgacg
     7141 ttctccacca ccactatcgc atcatcgacg agcagcccga tggcaagcac catcccgaac
     7201 atcgttagtg tgttgatgga gtaaccaaaa gcggcgagga tggcaaacgt ccctaacaac
     7261 accacgggta ccgcaatggt ggggatcagc gttgctcgca tattctgcaa gaacagatac
     7321 atcaccagga acaccagcat aatggcttcg aacagcgttt ttaccacttc gtgaatagaa
     7381 agctggacga atggcgtggt gtcataaggg tagagaacct tcattccctg cgggaagaat
     7441 ggctgtaatt ccgccagttt tgccttaatg gctttcgcgg tatcgagagc attcgcgccg
     7501 gttgccagct taatccccag gcccgccgcc ggttttccgt tgatacgagc gataacgtta
     7561 tagttttcac cgccaagttc aacccgtgcg acatctttca ggcgtaccac cgagccgtca
     7621 ctgtttacgc gcagggtcac tttgccgaat tcttccggat tttttaaccg cgtttgagca
     7681 ataatcgagg cattcaactg ttgccctggt aacgctggcg ttccgcccaa ctgtccggca
     7741 gcgatctgat cgttctgtac cttcaactgg ttaatcacat caaccggtgt cagtttatat
     7801 ttgtttagca gatcggcgtc cagccagata cgcatcgcat actgtgcgcc gaaaagctgt
     7861 acgtcaccga cgccattcag acggctaagc gtatctttaa cgttagaggc cacatagtcc
     7921 gagatatcgt cctgtgtggt gtctgggtta tcagagacaa agcccgccac catcaaatag
     7981 ctgctactgg acttttcaac actgatcccc tgctgctgaa cctcctgcgg cagcaacggc
     8041 gtggcgagct ggagtttgtt ctgcacctgc acttgcgcga tatcaggatc ggtcccggac
     8101 tggaaggtaa gggtaattgt cacgctaccg gcggaatcgc tggtggagga catatacatc
     8161 aggttatcga taccattcat attctgttcg ataacctgcg tcaccgtatc ctgcacggtc
     8221 tgcgcatcag cacctggata gtttgccgaa acagaaaccg caggcggtgc aatggttgga
     8281 tactgagcga cgggcaattg taggatcgcc agtgcgcccg ccatcatcag aataatggcc
     8341 agcacccatg caaatatcgg tcgtcgaata aaaaagtttg ccatgtcaga ttaccttact
     8401 tcgatgcagt atctgcgggg gtatcggtag tggctttaac ctgctctccc ggacgcgctt
     8461 tttgcaggcc gctgacaatg acttgatcgc cagatttcag accttcgcta atcaaccatt
     8521 tatcgccaat cgcctgactg gcaacgacag ggcgcgcttc cacctgactt ttatcgttaa
     8581 caatcagcac ggttgcatca ccacgcggtg tgcggctaac gccttgttgc gggataagaa
     8641 tggcgtcagg ttggacgcct tcatcaatcc gtgcacgcac aaacataccc ggcaaaagcg
     8701 tatgttgcgg gttagggaag acagcacgta gggttatgga gccggtgctt tcatcaacgg
     8761 tcacatcaga gaattgcagc gtacctttca ggggataggt ttgaccgttt tccatgacca
     8821 actctacgtt gctggtggcg ttttccttat gcaaatttcc ttgctctacg gattgcttca
     8881 gcctcataaa atcgttgctg gattgggtca catcaacgta gataggatcg agctgctgga
     8941 cagtcgccag ttcagtcgtt tgcccattag tgacaagagc gccttcggtc acggtcgatt
     9001 tgccgatacg tccgctaatt ggcgcagtca ctttggtata agcgagattg atgcgagcgc
     9061 tttcgactgt ggcttttgcg gcaatcacgg cggcatcggc ctggcgagca tcagcaatgg
     9121 cctggtcgta ctcctgctgg ctgatgtatt tcgtacccac gagcggaacg taacgtttta
     9181 ccgtcaaatg cgcgatggcg gcggcggctt cacttttcgc cagttcgcct ttcgcgctgt
     9241 cataatttgc ctgataggtc gcgggatcga tctggtacag ggactggcct gcttgtacat
     9301 cgctgccttc agtgaaatta cgattcagta cgatcccgct aacctgtggg cgaacttcgg
     9361 ctatacggta agcattggtg cggcctggta attcagtctt aacttctaac ggggccgttt
     9421 tcacaatatg aacggtaacc tgcggttcac cgacgtgagc tttctcttct cccttatcgt
     9481 tacaaccggc gattaaagcc gcggagatca gaataaagga gggcaggagg aaaaacctgg
     9541 catgtttcgt cattactatt cctcaaaaaa ccaaaagcgc gttatttacc cagaaaggca
     9601 acgcgttaac tcgcagaaag aaaaatacag tttgctatcc tacaaattat cattcgtcga
     9661 tgtaaggaat agttatgaat actggcgtct caaggcacat aaacacaaaa aaagattaat
     9721 attctactgt
//
LOCUS       DAPHKZ010000153         9342 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.154, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000153 DAPHKZ010000000
VERSION     DAPHKZ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9342
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.154"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            287..550
                     /locus_tag="RH288_004043"
     CDS             287..550
                     /locus_tag="RH288_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDV4033047.1"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     gene            550..690
                     /gene="ykgO"
                     /locus_tag="RH288_004044"
     CDS             550..690
                     /gene="ykgO"
                     /locus_tag="RH288_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HDV4033048.1"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     gene            complement(725..952)
                     /locus_tag="RH288_004045"
     CDS             complement(725..952)
                     /locus_tag="RH288_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033049.1"
                     /translation="MQAAPQREETEWRVQSKRGLMPAYRGEAGQQVNIKIMEYSERNV
                     RQLASNEQEEYIPRKINVGVINTPTLIRSDY"
     gene            1776..2318
                     /gene="ecpR"
                     /locus_tag="RH288_004046"
                     /gene_synonym="matA"
     CDS             1776..2318
                     /gene="ecpR"
                     /locus_tag="RH288_004046"
                     /gene_synonym="matA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECP biosynthesis operon DNA-binding
                     transcriptional regulator EcpR"
                     /protein_id="HDV4033050.1"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLSTDSLSEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELVYVINGRFLRKDIKKDKITDREMEIIRMTAQGMQPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKIYKLVQ"
     gene            2393..2980
                     /gene="ecpA"
                     /locus_tag="RH288_004047"
                     /gene_synonym="matB"
     CDS             2393..2980
                     /gene="ecpA"
                     /locus_tag="RH288_004047"
                     /gene_synonym="matB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="common pilus major fimbrillin subunit EcpA"
                     /protein_id="HDV4033051.1"
                     /translation="MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            3038..3706
                     /gene="ecpB"
                     /locus_tag="RH288_004048"
                     /gene_synonym="yagY"
     CDS             3038..3706
                     /gene="ecpB"
                     /locus_tag="RH288_004048"
                     /gene_synonym="yagY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpB"
                     /protein_id="HDV4033052.1"
                     /translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIKNS
                     TDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASALIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     gene            3732..6257
                     /gene="ecpC"
                     /locus_tag="RH288_004049"
                     /gene_synonym="yagX"
     CDS             3732..6257
                     /gene="ecpC"
                     /locus_tag="RH288_004049"
                     /gene_synonym="yagX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher EcpC"
                     /protein_id="HDV4033053.1"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSKD
                     IGQSSVNTLSSNLSYNLGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSSIGSI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSNANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYVNTNLTANGSVGWQGKNIAASGRTDGNAGVIFNTGLEDDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSRLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     gene            6247..7890
                     /gene="ecpD"
                     /locus_tag="RH288_004050"
     CDS             6247..7890
                     /gene="ecpD"
                     /locus_tag="RH288_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial adhesin EcpD"
                     /protein_id="HDV4033054.1"
                     /translation="MRVNLLITMIIFALIWPVTALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYTGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYMQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            7859..8569
                     /gene="ecpE"
                     /locus_tag="RH288_004051"
     CDS             7859..8569
                     /gene="ecpE"
                     /locus_tag="RH288_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414823.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpE"
                     /protein_id="HDV4033055.1"
                     /translation="MFRRRGVTLTKALLTAVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNHTRRSPTGGVVSTEPVVVMDTILVVRPRQVQFKWS
                     FDKVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            8882..9211
                     /locus_tag="RH288_004052"
     CDS             8882..9211
                     /locus_tag="RH288_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDV4033056.1"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARA
                     KYGLTPL"
BASE COUNT         2479 a         2338 c         2306 g         2219 t
ORIGIN      
        1 cgtgggagag gaatacacgc tgtcaggtaa tcaatcatac tgcgataaat tatcggccag
       61 taaagtggag ataacctcca ttctcgaaaa atccatactc tcagcaaaac catcatcaat
      121 cactcatcca ggcgtttatg ggagcgtcac caatggctgc taacaatgcc agagttcccc
      181 gttgcgaaaa ttccacatcc acaaagagtc acagggattg agtgttgaaa tgatccggat
      241 gagcatgtat ctttatggtt atgttataac ataacaggta aaaatgatga agcccaatat
      301 ccatcctgag tatcgtactg tggtgttcca cgacaccagt gttgatgagt actttaaaat
      361 cggctcgact atcaaaacag accgtgagat tgagctggat ggcgtaacgt atccatacgt
      421 gacaattgat gtctcttcta aatcgcaccc gttctataca gggaagctga gaacagtggc
      481 atcagaagga aatgttgcac gattcaccca acgttttggt cgttttgtta gcacgaaaaa
      541 gggggcgtga tgaaagttct taactctctg cgtaccgcaa aagaacgcca tccagactgt
      601 cagattgtga agcgaaaagg acggctatat gtgatttgta aatctaatcc acgttttaag
      661 gccgttcagg gtcgtaagaa aaaacgttga ttcaaaattc gacggattaa cgatatttgt
      721 ctgattaata atcagatcgg attaatgttg gtgtgtttat aacaccaaca ttaattttcc
      781 tggggatata ttcttcctgt tcatttgagg ccaactgcct gacgtttctc tccgaatatt
      841 ccattatctt aatgttgact tgttgaccag cttcgcccct gtatgctggc atcaaccctc
      901 ttttagactg aacacgccac tcagtctcct ccctttgcgg cgcagcctgc attttcactc
      961 aaactgttaa gatgataaat gtggtaaatc tgttggtact aacataaaaa cgtttacgcc
     1021 acaggaacag tctgatccac cggtaacccc gtcgccgacg ttcgagtgcc agttagagta
     1081 acgcgcacag ataactgaat gcagtgccct gacaaaaagg ccatcgttcc tgtgacagct
     1141 ggcagccttc gtttaacttc acttaatctg gctcttgggg gcttaccgaa cagatgacgt
     1201 acatacgccc gttcaatttt ccattactta ttggaatgaa cacctgtaac cattttgtgc
     1261 ggcatgttaa tccattaaaa tatcttactg attggcaaat catcttcaat gacagctcat
     1321 catagtttta tattctatcc cttaccctta aaacttgttt ttttactagt ccatcacaca
     1381 gcgcattaag actattccta acacttcagg gcaaagttcc tgaccaatat aaaatgcaag
     1441 taagaattga acgttatatt gccaataacc ttatgaaacc aaatgtcttt ttcttcttat
     1501 caaaaaagca atattttcag tttttctaaa tattgactta accattgaat tccttttccg
     1561 ttcacatatt gacactcatc gggaaaaaaa acataaattt aagcccaatc gaaaataatt
     1621 aaacttaatc tcgtttaacc tttattgata tgtactacgt atcttattta cttccggttt
     1681 actaaggaaa ctgaatgcac ctgtaaaaat tacaggtttg gaaagtagtg acatggcaaa
     1741 gtgattacag tagggactat gaggttaaaa accatatgga atgtcaaaac cgttctgata
     1801 aatacatctg gtctccccat gacgcctact tctataaagg actatctgaa ctgattgtgg
     1861 atatcgacag attaatttat ctatcgttgg agaaaattag aaaagatttc gtgtttatca
     1921 atctcagtac ggattcttta tctgaattta taaaccgtga taatgaatgg ttatccgcgg
     1981 taaaggggaa acaggtcgta ttgattgcgg ccagaaagtc agaggcctta gcaaattatt
     2041 ggtattacaa tagcaatatt aggggcgtgg tatacgctgg actgagtcgt gatattagaa
     2101 aagaactggt ctatgtgatt aatggcaggt tcctgagaaa agatattaag aaagataaaa
     2161 tcacggaccg ggaaatggaa attatccgca tgacggccca gggaatgcaa cctaaatcga
     2221 ttgccagaat tgaaaattgt agtgtgaaga cagtgtatac ccatcggcgt aatgctgagg
     2281 ccaagctgta ctcaaaaata tataagttgg ttcagtaaac tccaggcaag ttagttttaa
     2341 aaaatgactc actgggacat cacgtcctca attcaactcg ggaagaaatg caatgaaaaa
     2401 aaaggttctg gcaatagctc tggtaacggt gtttaccggc atgggtgtgg cgcaggctgc
     2461 tgacgtaaca gctcaggctg tagcgacctg gtcggcaaca gccaaaaaag acaccaccag
     2521 taagctggtt gtgacgccac tcggtagcct ggcgttccag tatgccgaag gcattaaagg
     2581 ttttaactca cagaaaggtc tatttgacgt ggctatcgag ggtgactcaa cggctaccgc
     2641 ctttaaactg acctcacgtc ttatcaccaa cacattaacc cagttggata cctcaggttc
     2701 cacactgaat gtgggcgtgg attataacgg cgcggcagtc gaaaaaactg gcgataccgt
     2761 gatgatcgat accgccaacg gcgtactggg cggcaacctt agcccgctgg ctaacggtta
     2821 caatgccagc aatcgtacca ccgcacagga tggtttcacc ttctccatca tcagcggtac
     2881 caccaatggt accaccgcag taacagatta cagcactcta ccggaaggca tctggagcgg
     2941 cgacgttagc gtacagttcg acgcgacctg gaccagttaa tctctctgat gtaccagcag
     3001 gggtagcccc cctgctttat tcctggacgg aattgttatg aaaaagcacc ttctgcctct
     3061 cgctctgctg ttttccggaa tatctccggc ccaggcgctg gatgtcggcg atatatcatc
     3121 gtttatgaac agtgacagca gcacgctgag caaaacgatc aaaaacagta ccgacagtgg
     3181 tcgccttatc aatatccgtc tcgaacggct ctcttcaccg cttgacgacg ggcaggttat
     3241 ctcaatggac aagccggatg agttgctact cactcccgcc agcttgctgc tacccgccca
     3301 agccagcgaa gtgatccgct tcttctataa gggacccgca gatgaaaaag agcgctacta
     3361 ccgcattgtc tggtttgatc aggccctcag tgatgcgcag cgcgataatg ccaaccgcag
     3421 cgctgtggcc actgcttccg ccctcatcgg caccattctg gtcgtcgccc ctcgtcaggc
     3481 gaactaccac tttcagtacg ccaacggctc cctgacaaat acaggaaatg cgacgctgcg
     3541 gatcctcgcc tacggacctt gcctgaaagc cgccaacggt aaggagtgta aagagaatta
     3601 ctacctgatg ccgggcaagt cgcgtcgttt tacccgcgtg gacactgcgg ataacaaagg
     3661 acgggttgca ctttggcagg gtgataagtt cattcccgtg aaatagatag ctgtgcagat
     3721 ggataacgac aatgccttta cgacggttct ccccaggact gaaagcccag tttgccttcg
     3781 gcatggtctt tttgttcgtt cagcccgatg ccagcgctgc tgacataagt gcgcagcaaa
     3841 taggtggggt gattattccg caggccttca gtcaggcgct tcaggacggc atgagcgtcc
     3901 cgctctatat tcatctcgcc ggtagccagg gtcgccagga cgatcagcga atcggcagcg
     3961 cttttatctg gctggacgat ggacagctac gcatccggaa aatacagctg gaagagagtg
     4021 aagataacgc cagtgtcagc gaacaaactc gacagcagct gatggctctg gccaacgccc
     4081 cgttcaatga ggcccttacc atccccctga ctgacaacgc gcagctggat ctcagcttgc
     4141 gccaactgct gctgcagcta gtggtcaagc gcgaagcgct gggcaccgta ctacgctcac
     4201 gtagcaaaga catcgggcag tccagtgtta acaccctcag cagtaatctg agctataact
     4261 tgggcgtcta taacaaccag ttgcgtaacg gcgggagcaa cacatccagc tatctgtcgc
     4321 tgaataacgt tactgcactg cgcgaacatc atgtggtgct cgacggctcg ctgtacggga
     4381 tcggtagcgg tcaacaggac agtgaattat ataaagcgat gtatgaacgc gattttgccg
     4441 gtcaccgatt tgccggtgga atgctcgaca cctggaactt gcagtcctta gggccgatga
     4501 ccgccatttc agcagggaag atttacggcc tttcctgggg aaaccaggcc agctccacca
     4561 tcttcgacag cagccagtca gccacgccag tgatcgcctt tttaccggcg gcgggcgaag
     4621 tacatctcac ccgtgatggg cggctactaa gcgttcagaa cttcactatg ggcaatcatg
     4681 aagtggatac ccggggtcta ccgtacggga tttacgatgt ggaagttgag gtgatcgtta
     4741 acggtcgcgt gatcagcaaa cgcacccagc gggtcaataa gctgtttagc cgggggcgcg
     4801 gcgtcggtgc accactggcg tggcaggtat ggggcggtag ctttcatatg gatcgctggt
     4861 cggaaaacgg gaaaaagacg cgaccagcta aagagagttg gctagcaggt gcctcgacct
     4921 ccggctcatt gagtacgctt agctgggcgg caacgggata tggatacgat aatcaggcgg
     4981 tgggtgaaac ccgtctgacg ctgccgcttg ggggggcgat caacgttaac ctgcaaaata
     5041 tgctggccag tgacagctca tggagcagca tcggcagcat cagcgccact ctaccgggag
     5101 gctttagttc gctgtgggtt aatcaggaaa aaacccgcat tggcaatcaa ttgcgacgta
     5161 gcgatgccga caaccgtgca atcggcggca cactcaacct gaactcactg tggtcgaagc
     5221 tgggcacatt cagcatcagc tacaatgatg accgccgtta caacagccat tattacacgg
     5281 cagattacta tcaaaatgtc tacagcggta cctttggttc gcttggcctg cgggccggta
     5341 ttcagcgcta taacaacggc gacagcaacg ccaatacagg aaaatatatc gctctcgatc
     5401 tctcgctacc actgggcaac tggtttagcg cagggatgac tcatcaaaac ggctacacca
     5461 tggcaaacct gtcagcacgc aaacagtttg atgaaggaac cattcgcact gttggtgcca
     5521 atctgtcacg tgccatctcc ggcgataccg gtgatgacaa aaccctcagc ggcggggcgt
     5581 atgcacaatt cgacgctcgt tacgccagcg gaacgctgaa cgtcaatagc gcggcggacg
     5641 gctacgtcaa taccaacttg accgccaatg gcagcgtcgg ctggcagggt aaaaacattg
     5701 ctgccagcgg gcggactgat ggcaacgctg gggtgatatt caacaccggg ctggaggacg
     5761 acggtcagat cagcgccaaa atcaacgggc ggattttccc gcttaacggc aagcgtaact
     5821 atctcccgct ctctccctat ggaagatatg aggtggagtt acagaacagc aaaaactcac
     5881 tcgacagtta cgatatcgtc agcggccgca aaagtcgtct gactctctat ccaggcaatg
     5941 tcgctgtcat tgagccagag gtgaagcaga tggttaccgt ctccggtcgt atccgtgcgg
     6001 aagacggcac actgctggct aacgcacgga ttaacaacca tatcggccga acccgaaccg
     6061 atgaaaacgg cgagtttgtc atggacgtgg ataagaaata ccccactatc gattttcgct
     6121 acagtggcaa taaaacctgc gaagtggctc tggaactcaa ccaggcgcgc ggtgccgtct
     6181 gggtcggtga tgtggtctgc agcggcctct catcgtgggc ggcggtgacg cagacaggag
     6241 aagagaatga gagttaacct actaataacg atgataattt tcgcgctaat ctggccagta
     6301 actgcgctca gagcggcagt gagcaaaaca acctgggcgg atgcaccggc acgcgagttt
     6361 gtgtttgtcg aaaacaactc agacgacaac tttttcgtca ctcctggcgg ggcgctggat
     6421 ccgcgcctga ccggtgccaa ccgctggacc ggtttaaaat acactggttc aggaaccatc
     6481 tatcagcaaa gcctcggcta cattgataac ggttacaaca ccggccttta taccaactgg
     6541 aagtttgata tgtggctgga aaattcacca gtttcatctc ctttaactgg cttgcgctgc
     6601 atcaactggt acgctgggtg taatatgacc accagtctta tcctgccgca aaccaccgac
     6661 gccagtggat tttatggcgc gacggtgacc agcggcggcg cgaagtggat gcacggcatg
     6721 ttgtcagacg cgttttacca gtatatgcaa caaatgcccg tcggcagcag ctttacaatg
     6781 accatcaatg cctgccagac ctctgtgaac tatgacgcca gcagcggcgc acgctgtaag
     6841 gatcaggcct ccggcaactg gtatgttcgc aacgtcaccc atacgaaagc agcaaatcta
     6901 cggttgataa atacccactc gctggcggaa gtatttatca acagcgacgg agtaccgact
     6961 ctgggcgaag ggaacgccga ctgccggacg caaaccatcg gcagccgttc aggattaagt
     7021 tgtaagatgg ttaactatac cctgcaaaca aacggactca gcaacacctc aatccatata
     7081 ttcccggcga tcgccaactc gtcgttagcc tcggccgtcg gggcgtacga tatgcagttc
     7141 agtctgaatg gcagttcatg gaaaccggtg agcaataccg cctattacta caccttcaac
     7201 gagatgaaga gcgcagactc gatctatgtt ttcttctcga gcaacttctt taagcagatg
     7261 gtgaacctcg ggatcagcga tatcaacacc aaagatctat tcaactttcg ctttcagaac
     7321 accacatcac cggagtctgg ctggtatgaa ttttctacct ccaacacgct gattatcaaa
     7381 ccccgtgatt tcagcatcag tattatctcc gatgaatata ctcagacacc gtcgcgggag
     7441 ggatatgttg gcagcggcga gtcggcactc gatttcggct atatcgtaac caccagcggt
     7501 aaaacagctg ccgacgaagt gctgatcaag gtgaccggac ccgcgcaggt gattggcggg
     7561 cgctcctatt gtgtcttcag ctccgatgac ggtaaggcga aagtaccgtt cccggcgaca
     7621 ctttccttta ttacccgcaa cggagctaca aaaacctacg atgccgggtg cgatgatagc
     7681 tggcgggata tgaccgatgc gctgtggttg accacaccgt ggactgatat ctctggcgaa
     7741 gtggggcaga tggataagac cacagtcaaa ttttcgattc caatggataa cgccatttcg
     7801 ctgcgtacgg tagatgataa cggctggttt ggcgaagtca gcgcttcagg agagattcat
     7861 gttcaggcga cgtggcgtaa cattaactaa ggccctgctg acagcggtct gtatgctggc
     7921 ggcacctttg acacaggcga tttcggtcgg caatctgaca ttttcgctgc cgtccgagac
     7981 tgactttgtc agcaaacgtg tagtgaataa caacaaaagc gcacggatat accgtattgc
     8041 catcagtgct attgatagcc cgggcagcag tgaattgcgc acccgaccgg tggatggtga
     8101 actgcttttc gccccccgcc agctggcgtt gcaggctggt gagagcgagt attttaaatt
     8161 ttactatcat ggtccacggg ataaccgcga gcgctactac cgggtctcat ttcgcgaggt
     8221 ccccactcgt aaccatacaa gacgcagccc aaccggcggc gtggtcagca cggagccggt
     8281 ggtggtgatg gataccattc tggtagtacg accacgtcag gttcagttta aatggtcctt
     8341 cgacaaggtg acaggaacgg taagtaacac tggcaacaca tggtttaagc tactgattaa
     8401 gccaggatgt gattcgaccg aagaggaagg cgatgcctgg tatctacgtc cgggagacgt
     8461 ggttcatcag cctgagttac gtcagccggg gaatcactat ctggtctata acgacaaatt
     8521 cattaagatt agcgattcct gtccggctaa gcccccttcg gcggactaag acttatccat
     8581 cggtcgaggg aagaattcca cctcagagcc ccaaaaatcg tttaaatgat gtggaagcga
     8641 tcgtcaatat cacctgtaac gatgggcttt ctcatatgca caccatagtg ttcaggagac
     8701 acggaaaggt atcaggcagc ctgctaacga gtggtttaat cacgaattag tacgtaaaat
     8761 cggtaacggc tggaaatcat tcaatactca cactatcgaa agttccccag ccaaccgcgg
     8821 tacgttctta catacgatgt accgctgttc tctttacgat ttttagctgt actggtgaat
     8881 tatgagcaat ctgaatccat gcatgacgtg tggtgcctgt tgtgcatttt tccgcgtctc
     8941 tttttactgg gccgaagccg acgatgctgg cggtactatt cccgccaggc tcactgaaca
     9001 aatatcccct tttcaccgat gcatgagcgg taccaatcag aaaaaccccc gatgtattgc
     9061 ccttgcagga accccgggca aaaatgcctg ctgcacgata tataaaaatc gatcgtccac
     9121 atgcagagaa ttcgccatgt ctggtgagaa cggagtcgtc aatgaggctt gcaatcgtgc
     9181 aagggctaaa tacgggctga caccgttata aacatacaat aattaattgc actgccccgc
     9241 cagcgataat agcggggctt cgtttttcag gggtaacaaa acccgatact tcttctattt
     9301 gccagcaaca atgcctctct tctgtagcgt tcttcggatc ta
//
LOCUS       DAPHKZ010000154         9238 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.155, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000154 DAPHKZ010000000
VERSION     DAPHKZ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9238
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.155"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(143..219)
                     /locus_tag="RH288_004053"
     tRNA            complement(143..219)
                     /locus_tag="RH288_004053"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(183..185),aa:Asp,seq:gtc)
     gene            complement(352..1083)
                     /gene="dnaQ"
                     /locus_tag="RH288_004054"
     CDS             complement(352..1083)
                     /gene="dnaQ"
                     /locus_tag="RH288_004054"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HDV4033057.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFAT
                     DEEIAAHEARLDLVQKKGGSCLWRA"
     gene            1148..1615
                     /gene="rnhA"
                     /locus_tag="RH288_004055"
     CDS             1148..1615
                     /gene="rnhA"
                     /locus_tag="RH288_004055"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HDV4033058.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     gene            complement(1612..2334)
                     /locus_tag="RH288_004056"
     CDS             complement(1612..2334)
                     /locus_tag="RH288_004056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414749.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDV4033059.1"
                     /translation="MKPARVPQTVVAPDCWGDLPWGKLYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISFMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     gene            2368..3123
                     /gene="gloB"
                     /locus_tag="RH288_004057"
     CDS             2368..3123
                     /gene="gloB"
                     /locus_tag="RH288_004057"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HDV4033060.1"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     gene            3195..4553
                     /gene="mltD"
                     /locus_tag="RH288_004058"
     CDS             3195..4553
                     /gene="mltD"
                     /locus_tag="RH288_004058"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HDV4033061.1"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     gene            complement(4601..5197)
                     /locus_tag="RH288_004059"
                     /pseudo
     CDS             complement(4601..5197)
                     /locus_tag="RH288_004059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308233.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            complement(5228..6028)
                     /locus_tag="RH288_004060"
     CDS             complement(5228..6028)
                     /locus_tag="RH288_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDV4033062.1"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     gene            6269..7183
                     /locus_tag="RH288_004061"
     CDS             6269..7183
                     /locus_tag="RH288_004061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4033063.1"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIARRDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     gene            complement(7180..7983)
                     /gene="dkgB"
                     /locus_tag="RH288_004062"
     CDS             complement(7180..7983)
                     /gene="dkgB"
                     /locus_tag="RH288_004062"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HDV4033064.1"
                     /translation="MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
     gene            complement(8146..8222)
                     /locus_tag="RH288_004063"
     tRNA            complement(8146..8222)
                     /locus_tag="RH288_004063"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8186..8188),aa:Asp,seq:gtc)
     gene            complement(8277..8392)
                     /gene="rrf"
                     /locus_tag="RH288_004064"
     rRNA            complement(8277..8392)
                     /gene="rrf"
                     /locus_tag="RH288_004064"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(8488..>9238)
                     /locus_tag="RH288_004065"
     rRNA            complement(8488..>9238)
                     /locus_tag="RH288_004065"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         2431 a         2294 c         2228 g         2285 t
ORIGIN      
        1 taatgaatga gacaacaagc gagaatcacg cacctacgcc agagtaaaat cattgaacag
       61 agaaatggtg gaattcaaat acaaaaaaac cgcaaaatta aaaatcttgc ggctctctga
      121 actcattttc atgagtgaat agtggcggaa cggacgggac tcgaacccgc gaccccctgc
      181 gtgacaggca ggtattctaa ccgactgaac taccgctccg cgttgtgttc cgttgggaac
      241 gaggcgaata ttacggattg cctcgacctt cgtcaacggt ttttctcatc ttttgaatcg
      301 tttgctgcaa aaatcgccca agtcgctatt tttagcgcct ttcacaggta tttatgctcg
      361 ccagaggcaa cttccgcctt tcttctgcac cagatcgaga cgggcttcat gagctgcaat
      421 ctcttcatct gtcgcaaaaa caacgcgtaa cttacttgcc tgacgtacaa tgcgctgaat
      481 tgttgcttca ccttgttgct gttgtgtctc tccttccatc gcaaaagcca tcgacgtttg
      541 accaccggtc atcgccagat aaacttccgc aaggatctgg gcatcgagta atgccccgtg
      601 cagcgttcgt ttactgttat ctatttcgta gcgagcacat aacgcatcga ggctgttgcg
      661 cttaccggga aacattttcc tcgccaccgc aaggctatcg gtgaccttac agaaagtatt
      721 ggtcttcgga atatcgcgct taagcaacga aaactcgtag tccataaagc cgatatcgaa
      781 cgctgcgtta tggatcacca actccgcgcc gcgaatatag tccatgaact catcggctac
      841 ttcggcaaac gtgggcttat cgagcaaaaa ttcatcggca ataccatgta cgccaaaggc
      901 ttccggatcc accagccgat cgggtttgag ataaacatgg aagttattgc ccgtcaggcg
      961 acggttcacc acttcaacgg caccaatctc aatgatcttg tggccttcat agtgcgcacc
     1021 aatctggttc ataccggtgg tttcggtatc gagaacgatc tggcgtgtaa ttgcagtgct
     1081 catagcggtc atttatgtca gacttgtcgt tttacagttc gattcaatta caggaagtct
     1141 accagagatg cttaaacagg tagaaatttt caccgatggt tcgtgtctgg gcaatccagg
     1201 acctgggggt tacggcgcta ttttacgcta tcgcggacgc gagaaaacct ttagcgctgg
     1261 ctacacccgc accaccaaca accgtatgga gttgatggcc gctattgtcg cgctggaggc
     1321 gttaaaagaa cattgcgaag tcattttgag taccgacagc cagtatgtcc gccagggtat
     1381 cacccagtgg atccataact ggaaaaaacg tggctggaaa accgcagaca aaaaaccagt
     1441 aaaaaatgtc gatctctggc aacgtcttga tgctgcattg gggcagcatc aaatcaaatg
     1501 ggaatgggtt aaaggccatg ccggacaccc ggaaaacgaa cgctgtgatg aactggctcg
     1561 tgccgcggcg atgaatccca cactggaaga tacaggctac caagttgaag tttaagcctg
     1621 tggtttacga cattgccggg tggctccaac cgcctggcga attcgtggct tgtttttact
     1681 ctgtttcatc ggatttagcg ttaaaggaat agtccgtttc cgggcaacaa taagttgtaa
     1741 gcaaccaagc gcaggaatat gcgcattcaa tagttttcct ccgtgtttgt tccacgggag
     1801 aacgtggaaa cggctggcgt gtagcacttc aaaattcaac aaagagagcc agtccagctg
     1861 ccgcatcaga gtaaacatcc ggctgttata gggcgaggtt ttgcgcaata ccggcacaag
     1921 tttgcgtaat cccataaaac tgatgggatt gaagccacta atgaccagcc agccatcatc
     1981 aatcaatacc cgatcggctt cacgcaataa acgatgcgga tcggtgcacc acggcaatgt
     2041 atgtgccagt agacaaacat caacggattt atcggcaaaa ggaagatgaa gtgggtccgc
     2101 ctgtacctgg acgggcattc cttgcgcaga aacattcact tgatgagaaa ccgcgcacgc
     2161 ttcgcaattg atttctgcgc ttaaattgcc aatcttaagc agatgaaaac catacatttt
     2221 agtgaaccac gggttgagct ggcgctccag cgccttgcga taaagctttc cccagggcaa
     2281 atcgccccag caatcaggag ccacgacagt ttgagggact cttgccggtt tcatcacaac
     2341 cttccgtttc acactgagag gtaatctatg aatcttaaca gtattcccgc ctttgatgac
     2401 aattacatct gggttttgaa tgatgaagca ggtcgctgcc tgattgtcga tcccggagac
     2461 gcagagccag tattaaacgc cattgccgcc aataactggc aaccggaggc catatttctc
     2521 acccaccatc accacgatca cgttggcggc gtaaaagaac tggtggaaaa gtttccacaa
     2581 attgtggtgt atggtccaca agagacacaa gataagggaa caacacaggt agtcaaagat
     2641 ggcgaaactg ccttcgtttt ggggcatgaa tttagtgtaa ttgctacgcc gggtcacact
     2701 ttaggacata tctgttactt cagtaaacct tatctatttt gcggcgacac actgttttct
     2761 ggtgggtgtg gtcggttgtt tgaagggaca gcatcacaaa tgtatcaatc acttaaaaag
     2821 ttaagtgcgt tacctgacga tacattggta tgttgtgctc atgaatatac cttatcaaat
     2881 atgaagtttg ctttgagtat tcttccgcac gatttgtcca taaatgatta ttatcgtaaa
     2941 gttaaggagt tacgggcaaa aaatcaaata acactacccg taattctgaa aaatgagcgg
     3001 caaattaatg tttttttaag aacggaagat attgatttaa ttaatgtaat taatgaagaa
     3061 acattattgc aacaacctga agagcgtttt gcatggttaa ggtcaaagaa agataggttc
     3121 tgataaaact ttcttgtcat cggctccgtt cgccgttatg atcggtcgtc ttttaagcaa
     3181 ctattgacac acacatgaag gcaaaagcga tattactcgc ctctgtcctg ctcgtgggtt
     3241 gccagagtac cggcaacgtt caacagcacg cacagagcct ttctgcagct ggtcaagggg
     3301 aagcagcaaa gtttacaagt caggcacgat ggatggacga tgggacgtct atcgcgccag
     3361 atggtgactt gtgggctttc attggcgacg agctaaagat gggaattccg gaaaatgacc
     3421 ggattcgcga acagaaacag aaatatttac gcaataagag ctatctccac gatgtaactt
     3481 tacgggcaga gccgtatatg tactggatag cagggcaagt taaaaaacgt aacatgccta
     3541 tggaactggt actactaccc atagtggaga gcgcttttga tcctcacgca acgtctggcg
     3601 ccaatgccgc aggcatctgg cagatcattc cgagcacggg gcgcaattat ggtttgaaac
     3661 agacccgcaa ttatgacgcg cgtcgcgatg ttgttgcttc aacaactgcc gcgctgaata
     3721 tgatgcagcg tctgaacaaa atgtttgacg gcgactggct tctgaccgta gcggcttata
     3781 acagcggcga aggtcgggtc atgaaggcaa ttaaaacgaa caaagcgcgt gggaaatcca
     3841 cggacttctg gtcgttaccg ttgccgcagg aaacgaagca gtacgtgcct aaaatgctgg
     3901 cattgagtga tattctcaaa aacagcaagc gttatggcgt acgtctgcca acgaccgatg
     3961 aaagccgtgc tctggcgcgt gtgcacctga gcagcccggt tgaaatggcg aaggtagcag
     4021 atatggcggg gatttccgtc agcaagctga agacattcaa cgctggcgta aaaggctcca
     4081 cgctgggcgc aagtggcccg cagtacgtga tggtgccaaa gaagcatgca gatcaactgc
     4141 gtgaatctct ggcttcaggc gaaattgctg ctgtacagtc gacgctggtt gccgacaata
     4201 cgccgcttaa cagccgtgtt tacaccgtac gctctggcga cacgctttca agtatcgctt
     4261 cacgtctcgg cgtaagcacc aaagatttgc agcagtggaa caaactgcgc ggatctaagc
     4321 tgaagccagg ccaaagtttg acgattggtg caggcagtag cgcacagcga ctggcaaaca
     4381 acagcgatag cattacgtat cgtgtgcgca aaggcgattc gctttcaagc attgctaaac
     4441 gccacggcgt gaacatcaaa gatgtgatgc gctggaacag cgacactgcg aatctgcaac
     4501 caggcgataa gctgacgttg tttgtgaaaa acaacaacat gccagattcc tgacaaacca
     4561 gataataaaa aggcaccgat tcccccggtg ccttttttat ttatgccgct ttatgtgcat
     4621 ctaccatgat gatatcactg gtgaaaaagc catcattctg caaggcaaaa tacgttctca
     4681 cctctgtcga tgcgctctgt tggtaaatgc gaatagcgtc tactaacgct tctggcgtac
     4741 gcattctcgc gacccatgaa gaaaattcca gcggtaactt atctgtaatt aaattatcaa
     4801 ctatcagatt ggcttcattg attaacgtca accactcacc gctggcgtag tttcgtacgt
     4861 gagaggtatc gcgtaatgct tctaccgtct gtaaccagat gtcgcgcact gggtgacccg
     4921 gagacattac gtccatcaca atcagcctac cgccaggttt caatatccta ttcacttctc
     4981 gcagtgctgc accaacatca tgccagtgat gggcagaata acggctgata acaatatcaa
     5041 atgcgttatc ggcaaatggc agactttcgg catatccctg gcgggtggtg atatttttca
     5101 gttgccgggc ttcggcagct tgtgccacga catccagcat gtgggcagat aagtcatacg
     5161 ccaccaccgc gctcacgttt tgcgcagcgc caaacgttgg tctgccctgt ggcagacctg
     5221 acatacctta tttatcaggc ttgccgggac tgaattcaac gagtagcgga ttgtgatcgg
     5281 aagcgcgcgt aaccagtaca gaagcttcac tgacgttcag accacggtag aaaacaaaat
     5341 cgagcgggcg accaaacgcc cgacggcgct gatcatcggt aaaacgcacc tggcgcagcg
     5401 acatttcccg cgcaaagcga tataacgcgt tcatccttct acggctccag gcattgaaat
     5461 ctcccgccat aatgaccggg ccgctgtggt gagctatctg atcgccaata ggaagtaact
     5521 gcttactata gacatccacg cccagactga agttgacggc gtgtatatta accaccatca
     5581 acaggcgggt gtcaggtaat ggatagaccg tcaccagtgc cgacttcgcc agacgcaaaa
     5641 tgggttctcg ttcacgtaac gggcagcaat acactggatg tgccgccgaa agggtcatta
     5701 cgccagaagg atgttgtggc agcacgaaag cgggtacctg atcggcggca agatagttag
     5761 cggtcgcaaa ctgtactaac tctggcgttg tctgcgcttc ctgcaataac accagatgtg
     5821 catctttgcc gtagttcttt aataccgaca accattcagc gcgttgctgt ttgtatatgt
     5881 tccacaccag gatccgaata cgctcttcgg tacttaacgg ttccccaggt ggtaatgcct
     5941 ggccgatgct cgcaaaagac cccggcggta agatcctttc cgcaggttgt ccggcaacat
     6001 agcgcatggc ataggtgttt tttcgcactt ttgactttga aacctctatt acgtcaaccc
     6061 ttccgcactc gggagggttc tactgttata gggattttag ctcactcttt caacgagcaa
     6121 ttgtatattg ttatgtaagc aagtgcttac accggtcaga attttgctca ttatggagaa
     6181 cattaaatcg catgacatat cacgcatcct gatggtttaa tgacaaataa attcaaaata
     6241 tctcttctat tttgcaacag gagcaaaaat gaaagccacg tcggaagaac tcgccatttt
     6301 tgtttcggtc gtcgaaagcg gcagctttag ccgggcagcg gaacaattag ggcaagcaaa
     6361 ctcagcggta agccgggcgg tgaaaaagct ggagatgaaa cttggcgtta gcctgcttaa
     6421 tcggaccacg cgacaactta gcctgacgga agaaggcgag cgttattttc gtcgcgtaca
     6481 gtcaattttg caggagatgg cagcggcaga atcagaaatt atggagacgc gtaatacacc
     6541 gcgtggactg ttacggatcg atgccgcaac tccagtggtg ctgcactttc tgatgccgtt
     6601 aattaagcct ttccgtgaac gctatccgga agtcactttg tcgctagtct cctccgaaac
     6661 gattattaat ttgatcgaaa gaaaagtgga tgtcgcgata cgcgctggta cgttaacgga
     6721 ttccagctta cgtgccaggc cgttatttaa cagttatcga aaaattatcg cctcccccga
     6781 ttatatttcc cgctacggga agccagaaac gatcgacgat ttaaagcaac atatttgcct
     6841 gggattcact gaacccgctt ccctcaatac ctggccgata gcccgtagag atggacaatt
     6901 acatgaggtg aagtacggtt tgtcatccaa tagtggggaa acactgaaac agctttgcct
     6961 gagtggcaac gggattgcgt gtttgtccga ctacatgatc gacaaagaaa tcgctcgcgg
     7021 agaattggtg gagttaatgg cagataaagt gttgccagtg gaaatgccat tcagtgccgt
     7081 ctattacagc gaccgtgcgg taagtacgcg catccgggct tttatcgatt tccttagcga
     7141 gcatgtaaaa acagctcccg gaggagctgt cagagaggct taatcccatt caggagccag
     7201 accttccggg ctaaccaggc ggtcgttgca atccagtgcg gcgatcgctt ttttatcttc
     7261 ggcatcaagc tgtaaatttt gtgccttaag attactttcc aggtttttac gtttagtaga
     7321 agaaggaatt actgagtaac cttcccccat agcccacgcc agaatcactt gtgccggagt
     7381 cgcattgtgt ttagctgcga tacgagcaat aacctcatct ttcagggcct taccatacgc
     7441 cagcgtcata taggaagtaa tatggatgcc gtgctgttta gcccaggcaa ccactttacg
     7501 gttttgcaga taaggagaga gttcaatctg gttagtagcg atgttttcag caccaacagc
     7561 agcaatcgct ttttccatca acgggatcgt gaagttggaa ataccgatct cacgcgtcag
     7621 cccttgtttt ttggcttcca gcagcgcctg cataaactct tcaacagaga cttcatcgtt
     7681 tggtgacggc cagtggatta gcgtcagatc aacataatcg gtacgcaatt tttgcaggct
     7741 ctctttcaga cttgggatca atttgtcttt gctgagattt tcaatccaga ttttagtggt
     7801 gatgtagagt tcatgacgtg gcacgccact ttctgcaatc gcctgaccta ctgcggcttc
     7861 gttatcatag atttgtgcgg tatcaattgc gcgataacca agttcaagcg ccgttatcac
     7921 agatgaaata acaacgtcgt ctttcagacg gaaagtacct aaaccaaatg cagggatagc
     7981 cataatatgc ctcttttaat gctattttcg ttaactgagg tgattatggg cttcagactg
     8041 ttgaggaaaa agagcgtaaa atgcagagga tttttgcgat tctggcaata atagatatac
     8101 agacgaaaaa aaacctcgag cgttaactcg aggcttctta ataagtggcg gaacggacgg
     8161 gactcgaacc cgcgaccccc tgcgtgacag gcaggtattc taaccgactg aactaccgct
     8221 ccaccgaatt cttttacaac caccggtttt atgaccggct tactgcttaa tttgatgcct
     8281 ggcagttccc tactctcgca tgaggagacc ccacactacc atcggcgcta cggcgtttca
     8341 cttctgagtt cggcatgggg tcaggtggga ccaccgcgct acggccgcca ggcaaattct
     8401 gttttatcag accgcttctg cgttctgatt taatctgtat caggctgaaa atcttctctc
     8461 aatccgccaa aacaccttcg gcgttgtaag gttaagcctc acggttcatt agtaccggtt
     8521 agctcaacgc atcgctgcgc ttacacaccc ggcctatcaa cgtcgtcgtc ttcaacgttc
     8581 cttcaggacc cttaaagggt cagggagaac tcatctcggg gcaagtttcg tgcttagatg
     8641 ctttcagcac ttatctcttc cgcatttagc taccgggcag tgccattggc atgacaaccc
     8701 gaacaccagt gatgcgtcca ctccggtcct ctcgtactag gagcagcccc cctcagttct
     8761 ccagcgccca cggcagatag ggaccgaact gtctcacgac gttctaaacc cagctcgcgt
     8821 accactttaa atggcgaaca gccataccct tgggacctac ttcagcccca ggatgtgatg
     8881 agccgacatc gaggtgccaa acaccgccgt cgatatgaac tcttgggcgg tatcagcctg
     8941 ttatccccgg agtacctttt atccgttgag cgatggccct tccattcaga accaccggat
     9001 cactatgacc tgctttcgca cctgctcgcg ccgtcacgct cgcagtcaag ctggcttatg
     9061 ccattgcact aacctcctga tgtccgacca ggattagcca accttcgtgc tcctccgtta
     9121 ctctttagga ggagaccgcc ccagtcaaac tacccaccag acactgtccg caacccggat
     9181 tacgggtcaa cgttagaaca tcaaacatta aagggtggta tttcaaggtc ggctccat
//
LOCUS       DAPHKZ010000155         9167 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.156, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000155 DAPHKZ010000000
VERSION     DAPHKZ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9167
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.156"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..901
                     /locus_tag="RH288_004066"
     CDS             <1..901
                     /locus_tag="RH288_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HDV4033065.1"
                     /translation="CISPAKFHECFINLMRDCHSSDDKDVIAIDGKTLRHSSDKSHRR
                     GAIHVISAFSTMHSLVIGQIKTDKKSNEITAIPELINMLDIKGKIITTDAMGCQKDIA
                     EKIQKQGCDYLFAVKGNQGRLNKAFEEKFPLKELNNPEHDSYAMSEKSHGREEIRLHI
                     VCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSVDLTAEKFAT
                     AIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLR
                     RKMQKAAMERNYLASVLAGNGLS"
     gene            1172..3409
                     /gene="nrfB"
                     /locus_tag="RH288_004067"
     CDS             1172..3409
                     /gene="nrfB"
                     /locus_tag="RH288_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage adsorption protein NrfB"
                     /protein_id="HDV4033066.1"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYHI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMIQLLLLLAYESLWPDAWH
                     FLSIFSGSAWLMTLLWLNFGLMVNRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRALKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLENDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEQVAQLES
                     ENEGE"
     gene            3396..6368
                     /gene="nfrA"
                     /locus_tag="RH288_004068"
     CDS             3396..6368
                     /gene="nfrA"
                     /locus_tag="RH288_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage adsorption protein NfrA"
                     /protein_id="HDV4033067.1"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDARLERSLAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSDVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAGQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLNEN
                     KPLFTTDAQEKSWLYLLSKYSANPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYAVSVATRNKAEALRLARLLYQQEPANLTRLDQLTWQLMQN
                     EQSREAADLLLQRYPFQGDARVSQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPNAWQHRAVAYQAYQVEDYATALAAWQKISLHDMSNEDLLAAANTAQAAGNGAARDR
                     WLQQAEKRGLGSNALYWWLHAQRYIPGQPELALNDLTRSINIAPSANAYVARATIYRQ
                     RHNVPAAVSDLRAALELEPNNSNTQAALGYALWDSGDIAQSREMLEQAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WTFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEAEYRIGRNMLLEGDLLSVY
                     SRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFLAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     gene            6369..7259
                     /locus_tag="RH288_004069"
     CDS             6369..7259
                     /locus_tag="RH288_004069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4434 family protein"
                     /protein_id="HDV4033068.1"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQRALLFKRAAAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAAPGVTPDGWYISAEIDDLNWRSEAARQPLL
                     TWLNNEQRLISDVSAKPVYISSFFAGNMSPDGYRQLLEHVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSSAPASGIVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAHGILEY"
     gene            7442..8203
                     /gene="envY"
                     /locus_tag="RH288_004070"
     CDS             7442..8203
                     /gene="envY"
                     /locus_tag="RH288_004070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator EnvY"
                     /protein_id="HDV4033069.1"
                     /translation="MQLSSSKPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNV
                     IELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAA
                     NHSKQQPSKPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
                     HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQ
                     LCGYSSTSYFISVFKAFYGLTPLNYLAKQRQKVMW"
     gene            complement(8249..8325)
                     /locus_tag="RH288_004071"
     tRNA            complement(8249..8325)
                     /locus_tag="RH288_004071"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8289..8291),aa:Arg,seq:tct)
     gene            8568..>9167
                     /gene="fimZ"
                     /locus_tag="RH288_004072"
     CDS             8568..>9167
                     /gene="fimZ"
                     /locus_tag="RH288_004072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis transcriptional regulator
                     FimZ"
                     /protein_id="HDV4033070.1"
                     /translation="MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDY
                     LRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANG
                     FVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTITVLSNREVTILRY
                     LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVEL"
BASE COUNT         2368 a         2293 c         2312 g         2194 t
ORIGIN      
        1 ctgtatcagt cctgcaaaat ttcacgagtg ctttattaac ttgatgcgtg attgtcattc
       61 ttcagatgat aaagacgtca ttgcaattga tggaaaaacg ctccggcact cttctgacaa
      121 gagtcaccgc aggggagcga ttcatgtcat tagtgcgttc tcaacaatgc acagtctggt
      181 catcggacag atcaagacgg ataagaaatc taatgagatt acagctatcc ctgaacttat
      241 taacatgctg gatattaaag gaaaaatcat cacaaccgat gcgatgggtt gccagaaaga
      301 tattgcagag aagatacaaa aacagggatg tgattattta ttcgcggtaa aaggaaacca
      361 ggggcggcta aataaagcct ttgaggaaaa atttccgctg aaagaattaa ataatccaga
      421 gcatgacagt tacgcaatga gtgaaaagag tcacggcaga gaagaaatcc gtcttcatat
      481 tgtttgcgat gtccctgatg aacttattga tttcacgttt gaatggaaag ggctaaagaa
      541 attatgcgtg gcagtctcct ttcggtccat aatagcagaa caaaagaaag aaccagaaat
      601 gacggtcaga tattatatca gttctgttga tttaaccgca gagaagttcg ccacagcaat
      661 ccgaaaccac tggcacgtgg agaataagct gcactggcgt ctggacgtgg taatgaatga
      721 agacgactgc aaaataagaa gaggaaatgc agcagaatta ttttcaggga tacggcacat
      781 cgctattaat attttgacta atgataaggt attcaaggca gggttaagac gtaagatgca
      841 aaaagcagcc atggagagaa actatctggc gtcagtcctt gcggggaacg ggctttcgta
      901 atcttgccct gcctgctcac ctcctccagg cacttccact acatgatgac ctgctcggtg
      961 ccaccgctcc ttttcactat gatgttaacc tccccgtccc aggacaccat gcttttgtct
     1021 acattctacg caaacggcaa cttttataac cagtgtaaaa ataacgtgcc gcaatagtca
     1081 tacctattaa tggtaaaaag ctgtcacaat tcataaaaaa ccttaatata cgccacccta
     1141 aacataacca gcgttaatgt aaggtttttg tgtggactgg cttcttgatg tttttgctac
     1201 ctggctctac ggcttaaaag taatcgcgat aacgttagcg gtcatcatgt tcatcagcgg
     1261 gctggacgat ttttttattg atgtcgtcta ctgggtacgc cgcattaaac gcaagttgag
     1321 tgtttatcgc cgctacccgc gaatgagtta ccgcgaactg tataaaccag atgaaaaacc
     1381 gttagcgatt atggttccgg catggaatga aacgggcgtc atcggcaata tggccgagct
     1441 ggcggcgacc acgctcgact acgaaaacta tcatatcttt gttggcacct accccaacga
     1501 ccccgatact cagcgtgatg ttgacgaagt gtgcgctcgc ttcccgaatg tgcataaggt
     1561 agtctgcgcg cgtcctggcc ccaccagcaa agccgactgt ctgaacaacg tgctggacgc
     1621 catcacccaa tttgagcgta gcgccaattt cgcttttgct ggttttattc tgcatgacgc
     1681 cgaagatgtg atttcaccga tggaattgcg tctgttcaac tatctggtcg agcgtaaaga
     1741 tctgattcag atcccggtgt atccgttcga acgcgaatgg acgcacttca ccagcatgac
     1801 ttacattgat gagttttcag agctgcatgg caaagatgtt ccggtgcgtg aagccctcgc
     1861 cggacaagtg cccagcgcag gcgtcggcac ctgtttcagc cgccgcgccg tgaccgcact
     1921 gttagctgac ggtgatggta ttgctttcga cgtgcagagt cttactgaag attacgacat
     1981 tggcttccgc ctgaaagaaa aaggtatgac ggaaattttt gtccgttttc cggtggtgga
     2041 cgaagccaaa gaacgcgagc agcgtaaatt tttacagcac gcgcggacat caaacatgat
     2101 ctgcgtgcgc gaatatttcc ccgatacctt ttcgactgcg gttcgacaaa aatcccgctg
     2161 gatcatcggc attgttttcc aaggctttaa aacccataaa tggacctcca gcctgacgct
     2221 gaactacttt ctctggcgcg accgcaaagg ggcaatcagt aactttgtca gcttcctcgc
     2281 gatgctggtg atgatccagc ttttgctgtt gctggcgtat gaaagtttgt ggcccgatgc
     2341 ctggcatttc ctttctattt tcagcggcag cgcatggtta atgaccctgc tgtggctaaa
     2401 ctttggtttg atggttaacc gcatcgtgca gcgggtgatt ttcgttactg gctactacgg
     2461 cctgacgcag gggctgcttt ccgtcctgcg tcttttctgg ggcaacctga ttaacttcat
     2521 ggccaactgg cgcgcgctaa aacaggtact tcaacacggc gatccacgtc gcgtggcgtg
     2581 ggataaaaca acgcatgact tccccagcgt gactggcgat acccgctcgt tgcgcccgtt
     2641 aggtcaaatt ctgctggaaa atcaggtcat cactgaagaa caactcgata cagcactgcg
     2701 taatcgcgtc gaaggtctac gcctgggcgg ttcaatgctg atgcaggggc tgattagcgc
     2761 cgagcagctg gcacaggcgc tggcagagca aaacggcgtg gcgtgggaat ccatcgatgc
     2821 ctggcagatc ccttcctcgc tgattgccga aatgccggcc tccgtggcgc tgcattatgc
     2881 ggtactgccg ctgcgtctgg aaaatgacga gttaattgtc ggcagtgaag atggtattga
     2941 cccggtttcg ctggcggccc tgacgcgtaa agtcggacgc aaagtgcgtt acgtcattgt
     3001 tctgcgggga caaattgtca cagggttacg tcactggtat gcacgccgac gcggtcacga
     3061 tccgcgggca atgttgtaca atgcggttca gcatcagtgg ctcacggaac agcaggccgg
     3121 tgaaatctgg cggcaatatg tgccgcatca gttcctgttc gccgaaatac tgaccacgct
     3181 cggtcatatt aatcgttcag caattaacgt gttgttattg cgccatgaac gcagttctct
     3241 gccgctcggc aagtttttgg tcaccgaagg cgttatcagc caggaaacgt tggatcgcgt
     3301 cctgacaatt caacgcgaat tacaagtttc gatgcaatca ctattactca aagcaggttt
     3361 aaacacagaa caggttgcgc aactggagtc cgaaaatgaa ggagaataac cttaatcgcg
     3421 tcatcggatg gtctggttta ctgctgacgt ctttattgag taccagcgca ctcgcagaca
     3481 atatcggcac cagcgcagaa gagctgggtc tgagcgatta tcgccatttt gttatttatc
     3541 cccgtctcga taaggcgctg aaggcacaga aaaataacga cgaagcaacc gccatccgcg
     3601 aatttgaata tatacaccag caggtgccgg ataatattcc gctgacttta taccttgcgg
     3661 aagcctatcg ccattttggt catgatgacc gggcgcggct gttgcttgag gatcaactga
     3721 aacgtcaccc aggagatgcc cgacttgagc gcagtctggc ggctattcca gttgaagtga
     3781 aaagcgttac gactgttgaa gaactgcttg cccagcaaaa agcgtgcgat gctgcaccga
     3841 ccctgcgttg tcgcagtgat gtcgggcaga atgccctgcg gctggcacag ttacctgtcg
     3901 ccagagcgca actgaacgat gcgacgtttg ctgcatcgcc ggaaggaaaa acgctgcgaa
     3961 ccgatctgct gcaacgggca atctacctga aacaatggtc ccaggcagat acgctataca
     4021 atgaagcacg ccagcagaac acattaagcg cggcagaacg ccgtcagtgg tttgacgtgc
     4081 ttcttgccgg gcagctagac gatcggatcc tggcactgca atcacagggg atcttcaccg
     4141 atcctcagtc atatattact tacgcgaccg cgctggctta tcgtggcgaa aaagcacgcc
     4201 tccagcatta tctcaatgaa aataagccgc tgtttaccac ggacgcacaa gagaaaagtt
     4261 ggctctatct gttatctaaa tacagcgcca accccgttca ggcattggcg aattatacgg
     4321 tacagtttgc cgacaaccgc cagtatgttg ttggcgcgac gctaccggtg ctgttaaaag
     4381 aaggtcagta cgacgcagcg caaaaactgc tcgccaccct ccccgccaat gaaatgcttg
     4441 aggagcgtta tgctgtcagc gtggcgaccc gtaacaaggc tgaagctctg cgtctggcac
     4501 gcttgctgta tcagcaagaa ccggcaaatc ttacccgcct ggatcaacta acctggcaac
     4561 tgatgcagaa cgagcagtca cgcgaagctg ccgatttatt gctgcaacgc tatcctttcc
     4621 agggcgatgc gcgtgtcagc cagactttaa tggcgcgact ggcgtctctg ctggaaagtc
     4681 atccttacct ggcaacgccg gcgaaggtgg cgattttatc gaaaccctta ccgctggcgg
     4741 agcaacgtca gtggcaaagt cagttgccgg gtattgcaga taattgcccg gcaatagttc
     4801 gcttgctggg cgatatgtcg ccttcctacg atgccgccgc ctggaaccgt ctggcaaagt
     4861 gttatcggga cacgctaccc ggtgtggcgt tgtatgcatg gcttcaggcc gaacaacgac
     4921 aaccgaacgc ctggcaacat cgtgcggtag cctatcaggc gtatcaggtt gaggactacg
     4981 ccaccgcact ggcggcctgg cagaaaatca gtcttcacga catgagcaat gaggatctgc
     5041 ttgctgctgc caataccgcc caggcggcag gaaatggtgc ggctcgcgat cgctggctac
     5101 aacaggcaga aaaacgtgga ctgggaagca atgcgctcta ctggtggctg catgcgcaac
     5161 gttacattcc tggtcagccg gaactcgcac tgaacgatct cacgcgctca atcaatattg
     5221 cgccttctgc caacgcttac gttgcgcggg cgacaattta tcgccaacgt cataatgtcc
     5281 cggccgcggt gagtgatttg cgcgccgcgc tggaactgga accgaataat agcaacaccc
     5341 aggcagcgct tggttacgcc ttgtgggata gcggtgatat cgcacagtcg cgggaaatgc
     5401 tcgaacaggc gcataaaggg ctaccggacg atccggcact gatccgacaa ctggcctatg
     5461 tgaaccagcg tctggatgac atgcctgcga cgcagcacta cgcccggctg gtgattgatg
     5521 acattgataa tcaggcgctg ataaccccac tgaccccaga gcaaaatcag caacgcttca
     5581 atttccgccg tttgcatgag gaggtcggtc gccgctggac gttcagtttc gattcttcta
     5641 tcggcttgcg ttccggggca atgagcaccg ctaacaataa tgtcggcggc gcagcgccag
     5701 ggaaaagcta tcgtagctac gggcaactgg aagccgagta ccgcatcgga cgcaatatgc
     5761 tgctggaagg cgacctgctc tcagtttata gccgcgtctt tgccgatacc ggagaaaacg
     5821 gggtgatgat gccggtgaaa aatccgatgt ccggcaccgg tctacgctgg aagccgctgc
     5881 gcgatcagat ctttttcctc gccgtcgaac agcagttgcc gctgaacggg caaaatggcg
     5941 catccgatac catgctgcgc gccagcgcct cattctttaa tggcggcaaa tacagcgacg
     6001 aatggcaccc gaacggttca ggctggtttg cccaaaacct gtacctcgat gcggcgcaat
     6061 atatccgcca ggatattcag gcgtggacgg cagattatcg cgtcagctgg catcagaagg
     6121 tagctaacgg acagactatt gagccttacg ctcacgttca ggacaacggc tatcgtgata
     6181 aaggcactca gggcgcgcag cttggcggtg tcggggtccg ctggaatatc tggaccggcg
     6241 agacgcacta cgacgcctgg ccgcacaaag tcagtctcgg cgtcgagtat caacatacct
     6301 ttaaggcgat taatcaacgt aacggagagc gcaacaacgc gtttctcacc attggagtgc
     6361 actggtaaat gcgtaagttc attttcgtat tgctgacact gcttttggtc agcccttttt
     6421 cctttgcgat gaaaggtatt atctggcaac cacaaaaccg tgatagtcag gttaccgata
     6481 cccagtggca ggggctgatg agtcagttac gtttgcaagg cttcgatacc ctggttttgc
     6541 aatggacccg ttacggcgat gcattcaccc agccagaaca gcgcgcgtta ttgtttaagc
     6601 gggccgcagc tgcgcaacag gctggcctga agctgattgt cgggctgaac gccgatccgg
     6661 aattttttat gcaccagaaa cagtcgtccg cagcgctgga aagctatctt aatcgcctgc
     6721 tggctgccga tctccagcaa gccagattat ggagcgccgc gcctggcgta acgccggatg
     6781 gctggtacat cagcgcggaa attgacgacc tgaactggcg cagcgaagcc gcccgtcagc
     6841 ctttgctaac atggttaaac aacgagcagc ggctgattag cgatgtttca gcaaaaccgg
     6901 tttatatcag tagttttttc gccggaaaca tgtcgcccga tggctatcgc caactgctgg
     6961 aacacgttaa agcaaccggc gttaatgtct gggtacagga tggcagcggc gtggataaac
     7021 ttaccgctga acagcgtgaa cgttatctac aggccagcgc cgattgccaa agctccgccc
     7081 cagcaagcgg cattgtttat gaactgtttg tcgccggcaa aggcaaaacc tttacagcga
     7141 aaccgaaacc ggacgcagaa attgcctcgc tgttagcgaa acgttcctct tgcggtaaag
     7201 acactctcta tttctctctg cgctatttgc ccgtcgcgca cggcattctc gagtattaaa
     7261 tctcctccag gtaagtcggg tacgacctgg cttacctctt tcgctctcgt cagaattcca
     7321 tcaagattaa ttgctaaaaa gcgtgctaaa gaaagaagat cgttatcggc gaacgggccg
     7381 atcactcatg caggaagcat agatcctttg agcggagttt ctgatatctg aggagtgcga
     7441 aatgcaattg agcagcagta aaccttgcgt ggtgatcctg accgaaaaag aggtagaggt
     7501 aagcgtcaat aaccatgcta cgtttaccct tccgaaaaac tacctggccg ccttcgcgtg
     7561 caacaataac gtcattgaac tctcaacgtt aaatcacgta ttaatcaccc acatcaaccg
     7621 taacatcatc aacgattatc tgttgttttt aaataagaac ttaacctgtg taaagccctg
     7681 gtcgcggctg gctaccccgg ttatcgcttg tcatagccgt acaccggaag tgttccggct
     7741 agccgccaac cacagcaagc agcaacccag caaaccctgc gaagcggagt tgacgcgcgc
     7801 attgcttttt accgtattgt ctaactttct tgagcaatcg cggtttattg ccctactgat
     7861 gtatatctta cgcagcagcg tccgcgacag cgtctgccgc attattcaaa gcgatattca
     7921 gcactactgg aatctgcgaa ttgtcgccag ttcgctatgt ttaagcccca gcctgctcaa
     7981 aaagaaatta aaaaacgaaa ataccagcta tagccagatt gtcacagagt gtcgtatgcg
     8041 ttacgccgta cagatgttat tgatggataa caaaaatatc actcaggtgg cgcaattatg
     8101 tggctatagc agcacgtcgt actttatctc tgtttttaag gcgttttacg gcctgacacc
     8161 gttgaattat ctcgccaaac agcgacaaaa agtgatgtgg tgaagggcaa agcggaaacg
     8221 gataagacgg gcataaatga agaagaaatg gcgcgccctg caggattcga acctgcggcc
     8281 cacgacttag aaggtcgttg ctctatccaa ctgagctaag ggcgcgttga taccgcaatg
     8341 cggtgtaatc gcgtgaatta tacggtcaac ccttgctgag tcaatggctt ttgatctggt
     8401 tgctgaacaa gtgaacgacc gcgtctgatt ttctgattta tttcgctata gtggcaaaca
     8461 aacgcacacc gctgcgcgtc tgaatcaaga aaacccgtat tttcatgtat caaagtacaa
     8521 tttaccgccc taacggaaaa ttgtccgctc ctatgagact ggtaactatg aaaccaacgt
     8581 cggtgatcat tatggatact catcctatca tcagaatgtc tattgaagtt ctgttgcaaa
     8641 aaaacagtga attgcagatt gtcctgaaaa cggatgatta ccgcataacc atcgattatc
     8701 tccgaacccg tcctgttgat ttaatcatta tggatataga cttacccgga acagacggtt
     8761 ttaccttcct gaaaaggatc aaacaaatcc agagcacagt gaaagtgtta tttttatcat
     8821 cgaaatcaga atgcttttat gctggcagag cgatacaagc tggtgctaac ggttttgtca
     8881 gtaaatgcaa tgatcagaat gatatttttc atgccgttca gatgatcctc tccggataca
     8941 cgttttttcc tagcgaaacg cttaactata taaaaagcaa taaatgtagt acgaatagtt
     9001 caacgatcac tgtgctatct aatcgtgaag tgaccatatt acgttatctg gttagcggat
     9061 tatctaataa agaaattgcc gataagttat tacttagcaa taaaacagtt agtgcgcata
     9121 aatctaatat ttatggcaag ctaggtttgc attcaattgt agagctt
//
LOCUS       DAPHKZ010000156         9155 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.157, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000156 DAPHKZ010000000
VERSION     DAPHKZ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9155
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.157"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            12..926
                     /locus_tag="RH288_004073"
     CDS             12..926
                     /locus_tag="RH288_004073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033071.1"
                     /translation="MPMILVKKNPRGKVIRELSSEEETAVKTVCGLKRPATMAQHNLA
                     NDLLREMREYDAWLQCDCIPGDSPAMNFAALKNNTGTLYLSSFNHEHAPECPMYRQLS
                     GNEEETSFGASRHPVSTRINYRNFLPPDDSNSVIRLQARSAYHNGERSSVRKKRPRLG
                     RLLLSLIEDAGLNKLDSLANPRIRTNYRECLDAIRQVTLQQEYIRGRALSEIIHFRPG
                     MSERSQERLMETLENSERHWPARRKHMFFQIFMAQHICRDAVEIHWANGNIQVIRPVR
                     GISINGEAQGGIRPPYWVLDSTSVLQKA"
     gene            1079..2341
                     /locus_tag="RH288_004074"
     CDS             1079..2341
                     /locus_tag="RH288_004074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEc9 family transposase"
                     /protein_id="HDV4033072.1"
                     /translation="MINKIDFKAKNLTSNAGLFLLLENAKSNGIFDFIENDLVFDNDS
                     TNKIKMNHIKTMLCGHFIGIDKLERLKLLQNDPLVNEFDISVKEPETVSRFLGNFNFK
                     TTQMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYN
                     IQFAFCDELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSDDLEILFRMDSGYFDEK
                     IIETIESLGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRETTELYTKLVKWEKDRRF
                     VVSRVLKPEKERAQLSLLEGSEYDYFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKY
                     DMAVGHLLLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAA
                     KIIKTARYVIMKLSENYPYKGVYEKCLV"
     gene            2665..3810
                     /locus_tag="RH288_004075"
     CDS             2665..3810
                     /locus_tag="RH288_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C beta-lactamase CMY-2"
                     /protein_id="HDV4033073.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQA
                     IPGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGE
                     IKLSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQP
                     QWTPGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKD
                     YAWGYREGKPVHVSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQ
                     SRYWRIGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVH
                     KTGSTGGFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
     gene            3904..4437
                     /locus_tag="RH288_004076"
     CDS             3904..4437
                     /locus_tag="RH288_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HDV4033074.1"
                     /translation="MRILPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLDKVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGDPSRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEMKQQMLAIAT
                     REGFEVNKLIWVKQPGA"
     gene            complement(4434..4751)
                     /gene="sugE"
                     /locus_tag="RH288_004077"
     CDS             complement(4434..4751)
                     /gene="sugE"
                     /locus_tag="RH288_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDV4033075.1"
                     /translation="MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIA
                     MLSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKL
                     STH"
     gene            4803..5273
                     /locus_tag="RH288_004078"
                     /pseudo
     CDS             4803..5273
                     /locus_tag="RH288_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632353.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5552..7432
                     /locus_tag="RH288_004079"
     CDS             5552..7432
                     /locus_tag="RH288_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin 1B"
                     /protein_id="HDV4033076.1"
                     /translation="MSDPVRITNPGAESLGYDSDGHEIMAVDIYVNPPRVDVFHGTPP
                     AWSSFGNKTIWGGNEWVDDSPTRSDIEKRDKEITAYKNTLSAQQKENENKRTEAGKRL
                     SAAIAAREKDENTLKTLRAGNADAADITRQEFRLLQAELREYGFRTEIAGYDALRLHT
                     ESRMLFADADSLRISPREARSLIEQAEKRQKDAQNADKKAADMLAEYERRKGILDTRL
                     SELEKNGGAALAVLDAQQARLLGQQTRNDRAISEARNKLSSVTESLKTARNALTRAEQ
                     QLTQQKNTPDGKTIVSPEKFPGRSSTNHSIVVSGDPRFAGTIKITTSAVIDNRANLNY
                     LLTHSGLDYKRNILNDRNPVVTEDVEGDKKIYNAEVAEWDKLRQRLLDARNKITSAES
                     AINSARNNVSARTNEQKHANDALNALLKEKENIRSQLADINQKIAEEKRKRDEINMVK
                     DAIKLTSDFYRTIYDEFGKQASELAKELASVSQGKQIKSVDDALNAFDKFRNNLNKKY
                     NIQDRMAISKALEAINQVHMAENFKLFSKAFGFTGKVIDRYDVAVELQKAVKTDNWRP
                     FFVKLESLAAGRAASAVTAWAFSVMLGTPVGILGFAIIMAAVSALVNDKFIEQVNKLI
                     GI"
     gene            complement(7450..7797)
                     /locus_tag="RH288_004080"
     CDS             complement(7450..7797)
                     /locus_tag="RH288_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin 1B immunity protein"
                     /protein_id="HDV4033077.1"
                     /translation="MKLDISVKYLLKSLIPILIILTVFYLGWKDNQENARMFYAFIGC
                     IISAITFPFSMRIIQKMVIRFTGKEFWQKDFFTNPVGGSLTAIFELFCFVISVPVVAI
                     YLIFILCKALSGK"
     gene            7916..8263
                     /locus_tag="RH288_004081"
     CDS             7916..8263
                     /locus_tag="RH288_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033078.1"
                     /translation="MTFEQKKARAIALMDSKKMWRSNYAPPLLRILWRLGIRLPPLPF
                     MPFWQVAVLTGGLWGTSWGCAMWFIYWGPSGMVAGEAIIISITGGFLFGLLTASFHWW
                     RRKVNRLPPWDDV"
     gene            complement(8281..8871)
                     /locus_tag="RH288_004082"
     CDS             complement(8281..8871)
                     /locus_tag="RH288_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033079.1"
                     /translation="MTQSRRPSPLQRRVLIVLAALDEKRPGPVLTRDIERVLERSGEA
                     PVYGPNLRASCRRLEDAGWLRTLRAPNLQLAVELTDAGRAVAQPLLLAEQDRLRAEQR
                     AAEVVVLPLVPAAGLPADGTSATDLAVELNGITYQACRGDFVVRLDGSTCLQLWNKEG
                     RVVCLEGDPLEVAQWLQACHDAGIEVRVQINESSVP"
     gene            complement(8871..9125)
                     /locus_tag="RH288_004083"
     CDS             complement(8871..9125)
                     /locus_tag="RH288_004083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033080.1"
                     /translation="MDEERVFSLSYEQLTRIAEKNIRECGLDNQSARCISELKASALL
                     WLWYELAIHGAPQNNHAQARERIDTDYQRLKKLIWSEGDS"
BASE COUNT         2609 a         2059 c         2176 g         2311 t
ORIGIN      
        1 gtgctttcat tatgccaatg atacttgtaa agaagaatcc ccggggcaaa gtgattcggg
       61 agcttagcag tgaggaagag actgcagtaa agacggtctg tggactgaaa aggccagcaa
      121 ccatggcaca acataacctg gccaatgatc ttctccggga aatgcgtgag tatgatgcat
      181 ggttacagtg tgactgtatt ccgggagatt cgccggccat gaattttgct gctcttaaaa
      241 acaatacggg tactctttat ctgtccagtt ttaatcatga gcatgcacct gaatgcccca
      301 tgtatcgtca gttatccgga aatgaagagg aaacatcctt cggagcaagc cggcatcccg
      361 ttagcacccg tataaattac agaaactttt taccacctga tgacagtaat tctgttatca
      421 gactgcaggc ccgctctgct taccataatg gtgagcgctc ctccgttcgc aagaaacgtc
      481 cgcgccttgg ccgtttactc ctgtcgctta ttgaagatgc agggctgaat aaactggatt
      541 ccctggctaa tccccgtatc cggactaatt atcgtgagtg tcttgatgcc atacggcagg
      601 ttacactaca gcaggagtat attcggggaa gagccttatc tgaaattatc catttccggc
      661 caggaatgtc tgaaaggtct caggagcggt taatggaaac gctggagaat tcagaacgac
      721 actggcctgc cagaagaaag catatgttct ttcagatttt tatggcgcag cacatctgtc
      781 gtgatgctgt ggaaattcac tgggcgaacg gtaatattca ggtcatcaga cctgtgcggg
      841 ggatcagtat taatggtgaa gcgcagggcg gaatacgtcc cccttactgg gtcctagatt
      901 ctacgtcagt acttcaaaaa gcataatcaa agccttgata aatatgcatt ccttcgaaat
      961 tcagctttca cccattgggt gaaagaaaag tgctcaaaaa tatgttaaat tatcagcttt
     1021 tatgactcga tatatggtaa aataatagta agaaaagtag taaaaagggg ttctaattat
     1081 gattaataaa attgatttca aagctaagaa tctaacatca aatgcaggtc tttttctgct
     1141 ccttgagaat gcaaaaagca atgggatttt tgattttatt gaaaatgacc tcgtatttga
     1201 taatgactca acaaataaaa tcaagatgaa tcatataaag accatgctct gcggtcactt
     1261 cattggcatt gataagttag aacgtctaaa gctacttcaa aatgatcccc tcgtcaacga
     1321 gtttgatatt tccgtaaaag aacctgaaac agtgtcacgg tttctaggaa acttcaactt
     1381 caagacaacc caaatgttta gagacattaa ttttaaagtc tttaaaaaac tgctcactaa
     1441 aagtaaattg acatccatta cgattgatat tgatagtagt gtaattaacg tagaaggtca
     1501 tcaagaaggt gcgtcaaaag gatataatcc taagaaactg ggaaaccgat gctacaatat
     1561 ccaatttgca ttttgcgacg aattaaaagc atatgttacc ggatttgtaa gaagtggcaa
     1621 tacttacact gcaaacggtg ctgcggaaat gatcaaagaa attgttgcta acatcaaatc
     1681 agacgattta gaaattttat ttcgaatgga tagtggctac tttgatgaaa aaattatcga
     1741 aacgatagaa tctcttggat gcaaatattt aattaaagcc aaaagttatt ctacactcac
     1801 ctcacaagca acgaattcat caattgtatt cgttaaagga gaagaaggta gagaaactac
     1861 agaactgtat acaaaattag ttaaatggga aaaagacaga agatttgtcg tatctcgcgt
     1921 actgaaacca gaaaaagaaa gagcacaatt atcactttta gaaggttccg aatacgacta
     1981 ctttttcttt gtaacaaata ctaccttgct ttctgaaaaa gtagttatat actatgaaaa
     2041 gcgtggtaat gctgaaaact atatcaaaga agccaaatac gacatggcgg tgggtcatct
     2101 cttgctaaag tcattttggg cgaatgaagc cgtgtttcaa atgatgatgc tttcatataa
     2161 cctatttttg ttgttcaagt ttgattcctt ggactcttca gaatacagac agcaaataaa
     2221 gacctttcgt ttgaagtatg tatttcttgc agcaaaaata atcaaaaccg caagatatgt
     2281 aatcatgaag ttgtcggaaa actatccgta caagggagtg tatgaaaaat gtctggtata
     2341 ataagaatat catcaataaa attgagtgtt gctctgtgga taacttgcag agtttattaa
     2401 gtatcattgc agcaaagatg aaatcaatga tttatcaaaa atgattgaaa ggtggttgta
     2461 aataatgtta caatgtgtga gaagcagtct aaattcttcg tgaaatagtg atttttgaag
     2521 ctaataaaaa acacacgtgg aatttaggaa aaacttatat ctgctgctaa atttaaccgt
     2581 ttgtcaacac ggtgcaaatc aaacacactg attgcgtctg acgggcccgg acaccttttt
     2641 gcttttaatt acggaactga tttcatgatg aaaaaatcgt tatgctgcgc tctgctgctg
     2701 acagcctctt tctccacatt tgctgccgca aaaacagaac aacagattgc cgatatcgtt
     2761 aatcgcacca tcaccccgtt gatgcaggag caggctattc cgggtatggc cgttgccgtt
     2821 atctaccagg gaaaacccta ttatttcacc tggggtaaag ccgatatcgc caataaccac
     2881 ccagtcacgc agcaaacgct gtttgagcta ggatcggtta gtaagacgtt taacggcgtg
     2941 ttgggcggcg atgctatcgc ccgcggcgaa attaagctca gcgatccggt cacgaaatac
     3001 tggccagaac tgacaggcaa acagtggcag ggtatccgcc tgctgcactt agccacctat
     3061 acggcaggcg gcctaccgct gcagatcccc gatgacgtta gggataaagc cgcattactg
     3121 catttttatc aaaactggca gccgcaatgg actccgggcg ctaagcgact ttacgctaac
     3181 tccagcattg gtctgtttgg cgcgctggcg gtgaaaccct caggaatgag ttacgaagag
     3241 gcaatgacca gacgcgtcct gcaaccatta aaactggcgc atacctggat tacggttccg
     3301 cagaacgaac aaaaagatta tgcctggggc tatcgcgaag ggaagcccgt acacgtttct
     3361 ccgggacaac ttgacgccga agcctatggc gtgaaatcca gcgttattga tatggcccgc
     3421 tgggttcagg ccaacatgga tgccagccac gttcaggaga aaacgctcca gcagggcatt
     3481 gcgcttgcgc agtctcgcta ctggcgtatt ggcgatatgt accagggatt aggctgggag
     3541 atgctgaact ggccgctgaa agctgattcg atcatcaacg gcagcgacag caaagtggca
     3601 ttggcagcgc ttcccgccgt tgaggtaaac ccgcccgccc ccgcagtgaa agcctcatgg
     3661 gtgcataaaa cgggctccac tggtggattt ggcagctacg tagccttcgt tccagaaaaa
     3721 aaccttggca tcgtgatgct ggcaaacaaa agctatccta accctgtccg tgtcgaggcg
     3781 gcctggcgca ttcttgaaaa gctgcaataa ctgacgatga ggcccaggat attgggcctc
     3841 ctttctttct ctttttttcc tgttgtcatc tacacttaac aaaaatacag caaggaaaat
     3901 cccatgcgca ttttgcccgt cgttgctgca gttacggctg cattcctggt tgtcgcgtgt
     3961 agctccccga caccgccgaa aggcgttacc gtggtaaata actttgatgc caaacgctat
     4021 ctgggaacct ggtatgaaat tgcgcgcttc gaccatcgtt tcgagcgcgg attggataaa
     4081 gtgaccgcaa catacagctt gcgcgacgac ggcggcatca acgttattaa caagggctat
     4141 aaccctgaca gggagatgtg gcagaaaacg gaagggaaag cctatttcac cggcgaccca
     4201 agcagagccg cgcttaaggt ttcttttttc ggccccttct atggcgggta taacgtaatt
     4261 gcactcgacc gggaatatcg tcacgcgctg gtttgtggtc cggatcgcga ctacctgtgg
     4321 atcctttcac ggacccctac tatttcagat gaaatgaaac agcaaatgtt agccatcgcg
     4381 acccgggaag ggtttgaagt gaataaactg atttgggtga aacagcctgg cgcttagtga
     4441 gtgctcagct tcagaccaat aatgccagca acgatcagcc caaggctcag caaacgtgcc
     4501 gggctggcag actcacccag cagcaaaatc cctgtaatgg ccgccccaac agcgccaata
     4561 ccggtccaga ccgcataagc ggttcctaca ggcaacgtgc gcattgccca agagagcatg
     4621 gcgatactga cgatcatcgc cgcaatagtg ataatgcttg gcgtaagacg cgtaaaaccg
     4681 tgggtgtatt tcaggccaat cgcccagaca acttcgagca aacctgcaat taataaaacg
     4741 atccaggaca tatcaggctc cagaacaatg gggccgtccc cggtgaaaga agcgtttgca
     4801 ggtgggttat tcttgctttt tgccggagtg ccgatggcag aatcatctgc agtgaagggt
     4861 atgctcatgc tctttatcaa ctgacatgtc cggtgcctgt ggacagcaaa ctggaacgaa
     4921 acacgctcac tgctcttctg aatgtggcca gctggcttaa aagaaagcca ggtacgccgg
     4981 aattaagtct ggaaaggccc ctgtttgata cagaagttta tgttaatggt gaaaagaaat
     5041 atgtactgcc ggatttcatt gtcacagcaa gggctcctga cggaaagacg gccagagtgg
     5101 tcatcgaaac gatgggatat gaagacagtg attactgcgc gagaaaatcc aggcagcata
     5161 ccggcatgaa gcagattggt gttctgcata ccgatccacc gaaatggctg gataacgatc
     5221 atcccccttt taagaaacat atgtacggtg tttttatgca tctcaggtac tgagatattt
     5281 tgtggctcag ttctgtaact tttcccgtaa cattgtctgt tgttacggga aagtccggtt
     5341 tttgtattgc accagagaat acccagactg tgatgctgcc acagtgtcag caggctttct
     5401 gaacggtata acaccacttc atgttaatga taattactat cattaaatct tgacatgcca
     5461 ttttctcctt aataaattag tactgtatat gtatccatat acgtaagcag ttaattcatt
     5521 tgttttcctc agaggatgaa ggagataccg aatgtctgac cctgtacgta ttacaaatcc
     5581 cggtgcagaa tcgctgggat atgattcaga tggccatgaa attatggccg ttgatattta
     5641 tgtaaaccct ccacgtgtcg atgtctttca tggtaccccg cctgcatgga gttccttcgg
     5701 gaacaaaacc atctggggtg gaaacgagtg ggtcgatgat tccccaaccc gaagtgatat
     5761 cgaaaaaagg gacaaggaaa tcacagcgta caaaaacacg ctcagcgcgc agcagaaaga
     5821 gaatgagaat aagcgtactg aagctggaaa acgcctttct gcggcaattg ctgcaaggga
     5881 aaaagatgaa aacacactga aaacactccg tgccggaaac gcagatgccg ctgatattac
     5941 acgacaggag ttcagactcc tgcaggcaga gctgagagaa tacggattcc gtactgaaat
     6001 cgccggatat gatgccctcc ggctgcatac agagagccgg atgctgtttg ctgatgctga
     6061 ttctcttcgt atatctcccc gcgaggccag gtcgttaatc gaacaggctg aaaaacggca
     6121 gaaggatgcg cagaacgcag acaagaaggc cgctgatatg cttgctgaat acgagcgcag
     6181 aaaaggtatt ctggacacgc ggttgtcaga gctggaaaaa aatggcgggg cagcccttgc
     6241 cgttcttgat gcacaacagg cccgtctgct cgggcagcag acacggaatg acagggccat
     6301 ttcagaggcc cggaataaac tcagttcggt gacggaatcg cttaagacgg cccgtaatgc
     6361 attaaccaga gctgaacaac agctgacgca acagaaaaac acgcctgacg gcaaaacgat
     6421 agtttcccct gaaaaattcc cggggcgttc atcaacaaat cattctattg ttgtgagtgg
     6481 tgatccgagg tttgccggta cgataaaaat cacaaccagc gcggtcatcg ataaccgtgc
     6541 aaacctgaat tatcttctga cccattccgg tctggactat aaacgcaata ttctgaatga
     6601 ccggaatccg gtggtgacag aggatgtgga aggtgacaag aaaatttata atgctgaagt
     6661 tgctgaatgg gataagttac ggcaacgatt gcttgatgcc agaaataaaa tcacctctgc
     6721 tgaatctgcg ataaattcgg cgagaaataa cgtcagtgcc agaacaaatg aacaaaagca
     6781 tgcaaatgac gctcttaatg ccctgttgaa ggaaaaagag aatatccgta gccagcttgc
     6841 tgacatcaat cagaaaatag ctgaagagaa aagaaaaagg gatgaaataa atatggtaaa
     6901 ggatgccata aaactcacct ctgatttcta cagaacgata tatgatgagt tcggtaaaca
     6961 agcatccgaa cttgctaagg agctggcttc tgtatctcaa gggaaacaga ttaagagtgt
     7021 ggatgatgca ctgaacgctt ttgataaatt ccgtaataat ctgaacaaga aatataacat
     7081 acaagatcgc atggccattt ctaaagccct ggaagctatt aatcaggtcc atatggcgga
     7141 gaattttaag ctgttcagta aggcatttgg ttttaccgga aaagttattg atcgttatga
     7201 tgttgctgtg gagttacaaa aggctgtaaa aacggacaac tggcgtccat tttttgtaaa
     7261 acttgaatca ctggcagcag gaagagctgc ttcagcagtt acagcatggg cgttttccgt
     7321 catgctggga acccctgtag gtattctggg ttttgcaatt attatggcgg ctgtgagtgc
     7381 gcttgttaat gataagttta ttgagcaggt caataaactt attggtatct gacacataat
     7441 gatgcccttt cattttcctg aaagggcttt gcagagtata aaaattaagt aaatggcaac
     7501 cacaggaact gatataacga aacagaataa ttcaaatatt gcagttaagc ttccgccaac
     7561 tggatttgta aagaagtctt tttgccagaa ttctttccct gtaaacctta ttaccatttt
     7621 ctgtattatc ctcattgaaa aaggaaaagt aatggcactg ataatgcatc cgatgaacgc
     7681 ataaaacatt cttgcatttt cctggttatc tttccatccc agataaaaaa ctgtaagaat
     7741 aatgaggatt ggtatcaggc ttttcagtaa atactttaca gatatatcca gtttcatctg
     7801 gtttctcctt tattgttatc gtgtaccggt gcgtgataac ataatcacag catgataata
     7861 ataatcaata acaataagct gtgtcacgtt tacatcatgg aacggaggtg ctcctgtgac
     7921 ctttgagcag aaaaaagccc gggccattgc cctgatggac agcaaaaaga tgtggcggag
     7981 caattatgcc cctcctcttc tgcgtattct ctggcggctg ggtatccggc ttccgccatt
     8041 accctttatg ccgttctggc aggtcgcggt gctgacgggg ggcttatggg gcacttcctg
     8101 gggatgtgca atgtggttta tctactgggg gccgtcagga atggtggcag gtgaggccat
     8161 tattataagt atcacgggtg gttttttgtt cggactgctc acggcctctt tccactggtg
     8221 gcgcaggaaa gttaaccggc tgccaccatg ggatgacgtg taaaccatgc aggcatgttt
     8281 ttacgggacg ctactttcat ttatctgtac gcgaacctct attcctgcgt catgacaggc
     8341 ctgcagccac tgcgccactt ccagcggatc gccctccagg cataccaccc tgccttcttt
     8401 attccataac tgcagacagg tgctgccgtc gagacgcacc acaaaatccc cacggcaggc
     8461 ctgatacgtt atgccgttca gctctaccgc cagatcagtg gcagaagtgc cgtctgcggg
     8521 cagacctgct gccgggacca gcggcagtac gacgacttct gccgcacgct gttctgcccg
     8581 gaggcggtcc tgttctgcca gcagcagagg ctgtgccacg gcccggccgg cgtccgtcag
     8641 ctccactgcc agctgcaggt tcggagcgcg cagggtacga agccagccgg catcctccag
     8701 acgacggcag gaggcgcgca ggtttggccc gtagaccggg gcttccccgc ttcgctccag
     8761 cacccgttct atgtcccgcg tcagcacggg tcccggccgt ttttcatcaa gggcagccag
     8821 cacaatcagc actctccgct gcagtggcga cggtcggcgg ctctgagtca ttaactgtca
     8881 ccctccgacc agatgagttt tttgaggcgc tgataatcgg tatcgatgcg ttcccgggcc
     8941 tgtgcgtgat tgttctgtgg cgcaccatga atggccagtt cataccacaa ccacagcaga
     9001 gctgaggcct tcaattcact aatacacctg gcgctctggt tgtccagccc acattcacgg
     9061 atattttttt ccgctattcg ggttagttgc tcatagctga gtgaaaacac cctttcttca
     9121 tccatcctgc acgctccatc tgataatgtt ctgac
//
LOCUS       DAPHKZ010000157         9035 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.158, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000157 DAPHKZ010000000
VERSION     DAPHKZ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9035
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.158"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..1804
                     /gene="espL4"
                     /locus_tag="RH288_004084"
                     /pseudo
     CDS             1..1804
                     /gene="espL4"
                     /locus_tag="RH288_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418441.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="type III secretion system effector EspL4"
     gene            complement(1773..3509)
                     /gene="aceK"
                     /locus_tag="RH288_004085"
     CDS             complement(1773..3509)
                     /gene="aceK"
                     /locus_tag="RH288_004085"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HDV4033081.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
                     PLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSG
                     TLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRV
                     FKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMEL
                     LLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRR
                     QRFSVRYGEMLF"
     gene            complement(3790..5094)
                     /gene="aceA"
                     /locus_tag="RH288_004086"
     CDS             complement(3790..5094)
                     /gene="aceA"
                     /locus_tag="RH288_004086"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HDV4033082.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLA
                     ASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF"
     gene            complement(5124..6725)
                     /gene="aceB"
                     /locus_tag="RH288_004087"
     CDS             complement(5124..6725)
                     /gene="aceB"
                     /locus_tag="RH288_004087"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HDV4033083.1"
                     /translation="MTEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQR
                     NKLLAARIQQQQDIDNGTLPDFISETASIRDADWKIRGIPADLEDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQS
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDEEHNNQVLNKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEV
                     MREQDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHQKTLSNGKPVTKALFRQMLGEEMKVIASELGEERFSQGRFDDAA
                     RLMEQITTSDELIDFLTLPGYRLLA"
     gene            complement(6994..7923)
                     /gene="metA"
                     /locus_tag="RH288_004088"
     CDS             complement(6994..7923)
                     /gene="metA"
                     /locus_tag="RH288_004088"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDV4033084.1"
                     /translation="MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQDQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAQTLAQEFFRDVEAGLDPDVPYNYFPHNDPQNTPRAS
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
     gene            8080..8523
                     /locus_tag="RH288_004089"
     CDS             8080..8523
                     /locus_tag="RH288_004089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDV4033085.1"
                     /translation="MVISIRRSRHEEGEELVAIWCRSVDATHDFLSAEYRTELEDLVR
                     SFLPEAPLWVAVNERDQPVGFMLLSGQHMDALFIDPDVRGCGVGRVLVEHALSMAPEL
                     TTNVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLNLAYVGA"
     gene            complement(8586..8969)
                     /locus_tag="RH288_004090"
     CDS             complement(8586..8969)
                     /locus_tag="RH288_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033086.1"
                     /translation="MSVLYIQIRRNQITVRDLESKREVSGDAAFSNQRLLIANFFVAE
                     KVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVAGATLMK
                     YRQFHIHAQSAVLSDSAVMAMLKQK"
BASE COUNT         2320 a         2203 c         2220 g         2292 t
ORIGIN      
        1 atagaaaaga aaaagaattc ccaagaatta aacttaatgg tcaatgttat tttccggggc
       61 gaccccaaaa ccgtatagta tgccgacaca ttgctgcaca atatattaat gatatttatc
      121 agaatgttga ttacaaaccc catcaagatg attactcttc agctgaaaaa tttctcacgc
      181 acttcaacaa aaaatgcaaa aaccagactt tggcgttggt ttccagccgt cctgaggggc
      241 gttgcgttgc tgcctgcggt gatttcgggc tagttatgaa agcatatttt gacaagatgg
      301 aatcaaatgg catcagtgtt atggcagcca tattactggt ggataaccat gctttgacgg
      361 tccggctaag aataaagaac acaactgaag gatgtaccca ttacgtggtt tcggtttatg
      421 atcctaatgt aactaacgat aaaataagaa ttatgagcga aagcaaagag aatattaaac
      481 actattctct gatggatttt atgaatgtag attatagcct cctgaaatgg tcaaatgatc
      541 atgttattaa tcaatctgtt gcaataattc cagcacttcc gaaagaacag ctattgatgt
      601 taaaaggatc tgtggatgaa ataacccctc cattatcacc tgcaacgatg aatttgctaa
      661 tggcaattgg tcagaatcac caacttacgc aactgatgat tcaactccag aaaatgccag
      721 aactacatag aacagaaatg ttgactgcct ataatagtat taacctgcca ggtttatatt
      781 tggctataaa ttatggtaat gcggatatcg ttgagactat tttcaattca ttgtcagaaa
      841 caggatatga aggattactc tcgaaaaaaa atctcatgca tattctggag gcaaaagata
      901 aaaatggttt ttctggatta tttttagcga tatcacgtaa ggataaaaat gttgtaacct
      961 cgattctgaa cgccttacct aaactggccg caacacatca tttagataac gaacaagtgt
     1021 ataaattcct gagtgccaaa aatagaacgt ccagccatgt tttataccat gttatggcga
     1081 atggtgatgc cgacatgctg aaaattgttt tgaacgcgtt acctttgtta attcgcacat
     1141 gtcatttgac taaagaacag gtactcgatc tcctgaaggc aaaggatttt tatggttgcc
     1201 caggactata tctggcgatg caaaatggac atagcgatat cgtgaaagtt attcttgaag
     1261 cattgcccag cctagcccag gaaattaaca tttcagcttc cgatattgta gatcttctga
     1321 ccgctaaaag tcttgcgcgc gacacgggtt tgtttatggc catgcagcgc ggacatatga
     1381 acgttattaa tactattttt aacgcattac ccactctgtt taatacgttt aaattcgata
     1441 aaaaaatatg aagcccctcc tcctggcaaa taattctaat gaatatcccg gtttgttttc
     1501 agcgatacag cataaacaac aaaatgttgt agagacggtt tatcttgctt tatctgacca
     1561 tgcacgcctg tttggattta ccgctgaaga tattatggat ttttggcaac acaaagcccc
     1621 acaaaaatac tctgcctttg agttggcttt tgaatttggt caccgggtta ttgctgaatt
     1681 aatccttaat acattaaata agatggctga aagctttggc tttacggata accctcgata
     1741 cattgcggag aaaaattata tggaagcttt actcaaaaaa gcatctcccc ataccgtacg
     1801 ctaaatcttt gcctgcgccg atacgcataa acatcttcca catgcccttc acgtatgcgg
     1861 ttttgtagtg cgcgccagta atcagcgcgg aacaggtcgg cgtgcatctc ttcaaacagc
     1921 ggaccaatac gcgggtcggc gcatagccag tggcgaaact cttccgggaa aacatcgccc
     1981 ggcgagacgc tgtaccacgg ttcgctggca agttcgtctt ccggatagcg cggcggcggg
     2041 atgtcgcgga aattcacttc cgtcatgtag caaatttcat cgtaatcata aaaaaccaca
     2101 cgcccgtgac gggtgacacc gaagttttta aacagcatgt cgccagggaa aatgttagca
     2161 gcggcaagct ggcgaatagc gttaccgtat tcttcaatgg cgtcgcgcaa ctgctgacct
     2221 tccacttgtt ccagccagat attgagcggc accatccgcc gctcaatata aagatggcga
     2281 atcacaattt gttcgccgag atcggtgatt ttttccgctg cttcctgaag cagtaattcc
     2341 attaatgccg gggaaatatg ccgcttctcc agcacaaagt tttcaaactc ctgggtgtcc
     2401 gccattcggc ccacgcgatc gtgctctttc accagttgat agcaggcacg aacgtgagcg
     2461 gcagacatct ctttctgcgg cgcgaacctg tctttgatga ctttgaatac ccgatcaaag
     2521 cccggcagcg taaacaccaa catcaccatt ccacgaatac ccggcgcttc aatgaactgc
     2581 tcattacagc cctgtagata aacgagatat tcgcggtagc tttcggtttt ggcgtgcttc
     2641 tggcagccga tagccatata caattcagcg gtggttttac ctggcagaat ttcccgtagc
     2701 cactcgacca gcgctgcggg cagcggcgca taaaccataa aataagaacg cgcaaagcca
     2761 aaaacaatgc tcgcttcggc ggtcgtcgtc aggcaggtat caataaataa ctcgccgtcg
     2821 tccgtctggt ggatcggcag caaaaatggc aatgtgccgg aaggtgtgat cagtttgcct
     2881 accagccagg cggctttatt gcggtaaaac agttcgttcg ccacctgtaa atgactttcc
     2941 gcgaggttgt ctgtccccag cgtttccgtc agatggcgaa taatgtaatg gatgtcacgg
     3001 cttttattct gccagcgcag gcgcagcggt aggtcgctga taacgcgcat cagtagagat
     3061 tcccagccgt gatcggggtg aaagtctttc gccagcgggc ggggaatggt acgaaagcgg
     3121 cgctctggct gagagctaaa gataaaaagc cgctcgggag taagcgagcg gtggtcaaat
     3181 aaccgacagt acacggagtt aaaaaagctc tccgcaatct cgaagcgcgg gtaatccggc
     3241 aacagccggg tgtaatgctc tttaacacgt agtaaaaatg ccgcgtccgt actttggccg
     3301 ttagtaatgc agcgcagttg ctccacgacc agaccaacgt gatgatcgta aagatggata
     3361 cggtttttca tcgcctgctg gacagcatgc cagtcggcct gttcgaaacg ctgctgcgca
     3421 ccggaggtca cttcgaggaa tcgaccatac tgagcatcga agccttgcaa aatggtttga
     3481 gcaatcaata attccaggcc acgcggcatt tagcgccctc atcaggagca gagaattgcc
     3541 ggatgcggcg taaacgcctt atccagccta cgttcggcaa cggttgtagg catgataaga
     3601 cgcgcaagcg tcgcatcagg catcgtgcac cgattgccgg atgcggcgta aatgccttat
     3661 ccggcctacg ttcggcaacg gctgtaggca tgataagacg cgcaagcgtc gcatcaggca
     3721 tcgtgcaccg attgccggat gcggcgtgaa cgccttatcc ggcctacagt cagcaacggt
     3781 tgttgttgct tagaactgcg attcttcagt ggagccggtc agcgcggtga ctgaagacgt
     3841 gccgccctga ataatagtcg tcactttatc gaagtaacct gtacccactt cctgctggtg
     3901 agatacgaag gtatagccat ctttcgcggc ggcaaattcc ggctgctgca ctttctcaac
     3961 gtagtgcttc ataccctcgc cctgggcata ggcgtttgcc aggtcaaaca tgttgaacca
     4021 catgctgtgg atacctgcca gggtgatgaa ctggaacttg tagcccatat ccgacagctg
     4081 ctgctggaag ctggcaatag ttttgtcgtc gaggtttttc tgccagttga acgacggcga
     4141 gcagttataa gccagcagtt tgcccggata tttcgcgtgg atagcttgtg caaagcgacg
     4201 cgccagttcc agatccggcg tggaggtttc acaccagacc aggtcagcat atggcgcata
     4261 cgccaggcca cggctgatcg cttgctcaat gcccgcatga gtacggaaga agccttcact
     4321 ggtacgctcg ccggtaataa attcgctgtc atacgggtcg caatcggagg tgatcagatc
     4381 cgccgcatca gcatcggtac gggcaaccag cagggttgga acgcccgtca cgtcagctgc
     4441 cagacgcgcc gcgaccagtt tctgaatagc ttcctgagtt ggcactaaaa ctttgccgcc
     4501 catgtgaccg catttcttca ctgacgccag ctgatcttcg aagtgaactg ccgctgcacc
     4561 ggcttcaatc atcgctttca tcagttcaaa ggcattcagg acaccgccaa aaccggcttc
     4621 cgcatcggca acgatcggca ggaagtaatc gacatagcgc ggatcgcccg gctcaatgcc
     4681 cgcggaccat tggatctgat cggcacgacg gaaggtgttg ttgatccgct ccaccacagc
     4741 tggcaccgag tttgccggat agagcgactg atccggatac atgctggccg ccaggttagc
     4801 gtccgccgct acctgccatc ccgacagata gactgcttca atacccgctt tcgcctgttg
     4861 cagcgcctga ccgccagtca gtgcgccgag gctgttgatg tagccttttt tcgactcacc
     4921 gtgcagcaga cgccacattt tcgctgcgcc cagttgcgcc agcgtgcatt caggattgac
     4981 tgaaccgcgt aatttcacca catcttccgc actgtatggg cgagtaatgc cttcccaacg
     5041 cggttgagtc cactctttct gtaattcttc aatttgttgt gtacgggttt tcatgtgcag
     5101 atgctccata gttatgtggt ggtttacgct aacaggcggt agcctggcag ggtcaggaaa
     5161 tcaattaact catcggaagt ggtgatctgt tccatcaagc gtgcggcatc gtcaaaacgc
     5221 ccctgggaga aacgttcttc gcccagttcg ctggcaatga ctttcatctc ttcgcccagc
     5281 atctggcgga acaaggcttt ggtcaccggt ttgccattgc tcaacgtttt ttgatgatgg
     5341 atccactgcc agatcgaggt acgggaaatt tcagccgtcg ccgcatcttc catcaggcca
     5401 taaatcggca cacagccgtt gccagagatc cacgcttcga tgtactgcac agccacgcga
     5461 atgttggcgc gcataccttc ttcggtgcgt tcaccatcac aaggtgccag cagctgatcg
     5521 gcagtaatcg gcgcgtcttg ttcgcgcatc acttcaagct gatttttacg ggagccgaga
     5581 atgtcgttga ataccgccat tgccgtgtcc gcaaggcctg ggtgagcgat ccatgtgcca
     5641 tcgtgaccgt tattggcttc cagcgattta tccgctttta ctttgttgag cacctggtta
     5701 ttgtgctctt catctttgct cggaataaac gccgccatgc cgcccatcgc aaaagcaccg
     5761 cgtttatggc aggttttaat caacaggcgt gagtaagcat tcaggaatgg tttatccatc
     5821 gtcactgcct gtctgtctgg caggacgcga tcgggatagt ttttcaacgt tttgatatag
     5881 ctgaagatgt aatcccaacg accgcagttc agaccaacaa tatggtcacg cagcgcgtga
     5941 aggatttcat ccatctggaa cacggcgggc agcgtttcaa tcagcaacgt cgccttgatg
     6001 gtgccgcgcg gcagattaaa gcgatcttct gcatagctga agacttcgct ccaccaggcc
     6061 gcttcctgcc aggactgggt tttcggcaga tagaaatagg gaccactgcc ctttgccaac
     6121 agtgcctgat agttgtggaa gaaatagagc gcaaaatcaa acaggctgcc ggggattgcc
     6181 tcaccacgcc aggtgacatg tttttccggc aagtgcagac cgcgtacccg acaaatcaaa
     6241 accgctggat tgggcttgag ctggtaaatt ttgcctgctt cattggtgta actgatggtg
     6301 ccgttaaccg catcacgcag gttaatttgc ccgtcgatca ctttgttcca gtctggtgcc
     6361 agtgaatctt cgaaatcggc cataaagact ttcacattgg cgttgagcgc gttgatcacc
     6421 atcttgcgct ctaccgggcc agttatctct acgcggcggt cttctaagtc cgcaggaatc
     6481 ccgcgaattt tccaatcagc atcgcgaatg gaagctgttt ccgaaataaa atcaggcaac
     6541 gttccgttat caatatcttg ctgctgctga atgcgcgctg ccagaagttt attgcgttgt
     6601 ggcgtaaaat gcgtcaccag ctcagtcaga aattctaccg cttcggcagt aagaatttgc
     6661 ttctcctgct cgccatacgg ccttgtgaaa gccagttcat cggttgttgt tgcctgttca
     6721 gtcatcgtgc agctcctcgt catggatccg aaaacttccc cactgtgaac gaaggatcgt
     6781 tgtgctcttt tcgttcagca caactaagac tactcattta aaatgcaaaa tcaaaaacaa
     6841 tttccatttt aattaaaaat acttgataac ttgttgataa caatatgaat aaaatttatt
     6901 cacctgctga ggtacgtttc ggaaataaaa aaggcacccg aaggtgcctg aggtaaggtg
     6961 ctgaatcgct taacgatcga ctatcacaga agattaatcc agcgttggat tcatgtgccg
     7021 tagatcgtat ggcgtgatct ggtagacgta atagttgagc cagttggtaa acagtaaatt
     7081 accgtgacta cgccagctcg ctcgcggtgt attttgcgga tcattgtgcg ggaaatagtt
     7141 atacggtaca tccgggtcta gtccggcttc cacatcgcgg aaaaattcct gcgccagcgt
     7201 ttgcgcatca tattcgggat ggcccgtcac aaaggcaatg cgcttatctt tactggcaaa
     7261 cagatatgca tccccttctt ccgtctctgc cagaatttcc agatcggtgt aatcacgaat
     7321 caacgctgcc ggaaagtcag catagcgcga atgcggtgcc aggaatgaat catcaaagcc
     7381 acgcgtcaga agcgcatgag gatggagaat atgatgctcg taaacgccag agagtttgtc
     7441 ggtgcgagtt tgcttaggaa tgccgtagag gatattgagc gcggcctgta ccgcccagca
     7501 gacaaacagc gtcgaggtga cgtgatcttt cgaccactcc agcacctgtt tgatctgcgg
     7561 ccagtaagcg acatcattaa actccaccag gcccagcggc gcaccagtta caatcaaacc
     7621 gtcaaagttc tgatcctgaa tatcttcaaa gttacagtag aagttgttca gatgctctgc
     7681 gggcgtgttg cgcgattcac gggaatcgat gcgcaacagc tgaatatcga cctgcaaagg
     7741 tgagtttgaa agcaggcgca gaaactgatt ttcagtttca atcttcttcg gcatcaggtt
     7801 aaggatcaga accttaagtg gacgaatttc ctgaccagac gcacgagaag ttgtcatcac
     7861 aaagacgttt tcttcacgca agaaattgac ggcgggtagc tcgtccggca cacgaatcgg
     7921 cataacctga ttacctcact acatacgctt atacgtttag acatccagat agctgaagat
     7981 aaccagaaaa tttgccaatg tcgagcctgc atgttgaagg tgagaaagtt tcaaggaaaa
     8041 gactacgtta gaatataaga atgactaaaa ggagagaaaa tggttattag tattcgccgc
     8101 tcacggcatg aggaagggga ggaactcgtt gcgatttggt gtcgttctgt cgatgccact
     8161 cacgattttc tatcagcaga gtatcggacc gagctggagg acctagttcg ttccttcctg
     8221 ccggaagcgc cgttgtgggt cgcggttaat gagcgggatc agccggttgg atttatgttg
     8281 ctaagtgggc agcatatgga tgcgctgttt atcgatcctg atgtgcgcgg ctgcggcgta
     8341 ggtcgggtgc tggtggagca tgcgctctcg atggcaccgg aactgacaac caacgttaat
     8401 gagcaaaatg agcaggcggt tgggttctat aagaaggtgg gttttaaggt tacgggacgc
     8461 tctgaggtgg acgatttggg gaaaccgtat ccgttgctga atctggcgta tgtgggggcg
     8521 taggcgattt tttctcatcc cggtgggctg aacttcaggt ttagtaccca ccaatggtga
     8581 cacgattatt tctgcttaag cattgccatg accgcactat cactgagtac cgctgattgc
     8641 gcatggatgt ggaactggcg atatttcatt aacgttgccc cagcgaccac ttcatggaga
     8701 atgcgttcct caacctgtga caaaccgccc tcattcattt ccagcgcgct cacaacaata
     8761 tccatacgtt ttgctggcaa aaaagaatgc caggttgaac gtgggtggag ttgcagaaca
     8821 agatcttgca gaactttttc tgcaacaaag aaattggcga ttaacaggcg ctggttactg
     8881 aaggcagcgt ctcctgacac ttcacgtttg ctttcaagat cgcgaacagt aatttgatta
     8941 cgacgaattt ggatatacag aactgacatg agattccctt catcatgcaa ataattgata
     9001 tgcaaaaaac cccggcctta tggaccgggg ttttt
//
LOCUS       DAPHKZ010000158         8929 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.159, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000158 DAPHKZ010000000
VERSION     DAPHKZ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8929
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.159"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..442)
                     /locus_tag="RH288_004091"
     CDS             complement(<1..442)
                     /locus_tag="RH288_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HDV4033087.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDIALPGPLPFILSRTYSSYRTKTPAPVGSLGPGWKMPADI
                     RLQLRDNTLILSDNGGRSLYFEHLFPGEDGYSRSESLWLVRGGVA"
     gene            complement(685..891)
                     /locus_tag="RH288_004092"
     CDS             complement(685..891)
                     /locus_tag="RH288_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HDV4033088.1"
                     /translation="MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMDQAEKATGDFY"
     gene            1204..1293
                     /gene="kdpF"
                     /locus_tag="RH288_004093"
     CDS             1204..1293
                     /gene="kdpF"
                     /locus_tag="RH288_004093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDV4033089.1"
                     /translation="MSAGVITGVLLVFLLLGYLVYALINAEAF"
     gene            1293..2966
                     /gene="kdpA"
                     /locus_tag="RH288_004094"
     CDS             1293..2966
                     /gene="kdpA"
                     /locus_tag="RH288_004094"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDV4033090.1"
                     /translation="MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVER
                     VLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLA
                     LNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
                     STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTDD
                     RRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGTDSSINMEGKESRFGVLVSSL
                     FAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLV
                     SKKSQAASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS"
     gene            2989..5037
                     /gene="kdpB"
                     /locus_tag="RH288_004095"
     CDS             2989..5037
                     /gene="kdpB"
                     /locus_tag="RH288_004095"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDV4033091.1"
                     /translation="MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSL
                     LTTCISIAMASGAMPGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNE
                     IALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGV
                     AGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLA
                     DAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRM
                     IRKGSVDAIRRHVEANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVK
                     GGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
                     EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGK
                     QMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMCLHSPDSAILSAVIFN
                     ALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
                     "
     gene            5046..5618
                     /gene="kdpC"
                     /locus_tag="RH288_004096"
     CDS             5046..5618
                     /gene="kdpC"
                     /locus_tag="RH288_004096"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDV4033092.1"
                     /translation="MSGLRPALSTFIFLLLITGGVYPLLTTVLGQWWFPWQANGSLIR
                     EGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKLIAARV
                     AALRAANPDASASVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIA
                     KYSQQPLVKYIGQPVVNIVELNLALDKLDE"
     gene            5611..8295
                     /gene="kdpD"
                     /locus_tag="RH288_004097"
     CDS             5611..8295
                     /gene="kdpD"
                     /locus_tag="RH288_004097"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HDV4033093.1"
                     /translation="MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAE
                     AQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPLKRQAYRGRHISEFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASR
                     LGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDNRSFK
                     DKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVV
                     ATVINVVSFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSPQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQG
                     MTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMI
                     PEQQRLLETFTLLVANALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAE
                     IGIDAHVEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIV
                     DVHGGTITAFNRPEGGACFRVTLPQQTAPELEEFHEDM"
     gene            8292..>8929
                     /gene="kdpE"
                     /locus_tag="RH288_004098"
     CDS             8292..>8929
                     /gene="kdpE"
                     /locus_tag="RH288_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HDV4033094.1"
                     /translation="MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHSATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRH"
BASE COUNT         1871 a         2348 c         2596 g         2114 t
ORIGIN      
        1 tcgccacgcc gccgcgcacc agccacagtg actcgctgcg gctgtaaccg tcctcaccgg
       61 gaaacaggtg ctcaaaatac aggcttctgc cgccgttatc actgagtatc agtgtgttat
      121 cgcgcagctg taagcggata tccgcaggca ttttccagcc ggggccgagg ctccccaccg
      181 gcgcgggcgt ttttgtccgg taactgctgt aggtgcggga gagaatgaac ggcagcgggc
      241 cgggcagggc gatgtcggtt tcaccgggaa ggacctttgc accgagcagc ggattgaccg
      301 gatggccgga cgtcaccccg ccggggcaca ccgaacaggc cacgccggtg ggggcaccga
      361 tgcgtacccc ggctgaaccc tggacaatgc taccgccata ctgcgtcatg tcgccctgac
      421 gcgccgccgg ttttccgctc atctgctcat ccttgtttta tcgggttatt tgtctgctga
      481 caggcgaaac cctacagatt tataagaaag ccttaagtga gatatctgtc agataagaac
      541 aattaggaaa atatttatat atatttcatg aatatatgtt tcgattggta taacgatgtc
      601 taaatattcc tctgaacatc ttcctgatac aaaaaaccgc cagcgtttcc gctggcggtt
      661 ttcaatgtat tcaaaactca gcaatcaata aaaatcacca gttgcctttt cggcctgatc
      721 catccacacc ggtttatcgc tggttttcga ccagacgcga tgcaggtagc tgtaaaagcg
      781 ggcgcggtct ttccagaaaa gcatgaaagg cagcgccaga acgcccgctg caaccgcata
      841 agtacggcgt aaaaagataa gccatgcagg atattctctg tagagttcca tacttttctc
      901 ccccttttgt atctacccgg tgaatggcac cggaaaaatg aatttgttta tctgatgaaa
      961 atagtaccgc cttttgtgta attttactac tcatccgacc acttattttt gcttattgat
     1021 ggtttattta cattcatcct gtaattaagt tacacaaaag ttaaattaat actaaacatt
     1081 agttaaatca tggcttttgc catttttata ctttttttac accccgcccg cagatttttg
     1141 cgaaatcttt gcagccagaa ttctaccctt ccggtatcac ttttaggcca ctggaggtgc
     1201 actgtgagtg caggcgtgat aaccggcgta ttgctggtgt ttttattact gggttatctg
     1261 gtttatgccc tgatcaatgc ggaggcgttc tgatggctgc gcaagggttc ttactgatcg
     1321 ccacgttttt actggtgtta atggtgctgg cgcgtccttt aggcagcggg ctggcgcggc
     1381 tgattaatga cattcctctt cccggtacaa cgggcgttga gcgcgtactt tttcgcgcac
     1441 ttggcgtctc tgaccgtgag atgaactgga agcaatatct ttgtgccatt ctcggcctga
     1501 acatgctggg gctggcggtg ctgtttttta tgttgctcgg tcagcactat ctgccgctta
     1561 atccacagca gttgccaggg ctgtcgtggg atctggcgct gaataccgcc gtcagctttg
     1621 tcaccaatac caactggcaa tcttatagcg gtgaaaccac gttgagctat ttcagccaga
     1681 tggcgggctt aacggtgcaa aactttcttt ctgccgccag cgggattgcg gtgatttttg
     1741 ccctcatccg tgcgtttacc cgccagagca tgagcacgct cgggaatgcc tgggtcgatc
     1801 tgctacgcat cacgttatgg gtgctagtcc ctgtggcgtt gttgattgca ctgtttttta
     1861 ttcaacaagg tgcgctgcaa aactttctgc cttatcaggc tgtgaatacc gttgaaggag
     1921 cgcaacagct gttacccatg gggcctgtag cttctcagga agcgatcaag atgctcggta
     1981 ctaacggcgg tggcttcttt aatgccaact cgtcgcatcc gtttgaaaac ccaaccgcac
     2041 tgaccaactt cgtgcagatg ctggcgatct tcttgatccc aacggcgctg tgctttgcct
     2101 ttggtgaagt gacggacgat cgccgccagg ggcgcatgtt gctgtgggcg atgtcagtga
     2161 tttttgtcat ctgcgtaggc gtggtgatgt gggcagaagt tcagggtaat cctcatctgc
     2221 tggcactggg cacggacagc agcatcaata tggaaggtaa agagagccgt ttcggcgtgc
     2281 tggtcagtag cctgtttgcg gtcgtgacga cggcggcttc ctgtggcgcg gtgattgcga
     2341 tgcatgattc gtttaccgct ctcggtggca tggtgccgat gtggctgatg caaattggtg
     2401 aagtggtgtt cggcggtgtc ggttctggtc tttacggcat gatgctgttt gtcctgctgg
     2461 cggtgtttat tgccgggctg atgattggtc gtacaccgga atatctgggt aaaaaaatcg
     2521 acgtacgcga gatgaaactg actgcactgg caattctggt taccccgacg ctggtgctga
     2581 tgggcgcggc gttggcgatg atgaccgacg ccggacgtag cgccatgctc aaccctggcc
     2641 cgcatggttt tagcgaagtg ctgtacgccg tgtcatccgc cgctaacaac aacggcagcg
     2701 cctttgccgg attaagcgcc aactctccgt tctggaactg tttactggcg ttctgcatgt
     2761 ttgtcggtcg cttcggggtg attatcccgg tgatggcaat tgccggttcg ctggtgagta
     2821 aaaagagcca agccgccagc tccggcacgc tgccaacgca cggcccgctg tttgttggcc
     2881 tgttaatcgg caccgtgttg ctggttggcg cactgacctt tatccctgcc ctggcgcttg
     2941 gtccggtggc ggaatatctc tcctgatgat attgagtgag cactgaatat gagtcgtaaa
     3001 caactggcgc tattcgaacc aacacttgtc gttcaggcgc tgaaagaagc ggtgaaaaaa
     3061 ttaaacccgc aggcgcaatg gcgcaatccg gtgatgttta tcgtctggat cggcagtctg
     3121 ctgaccacct gtattagcat cgcgatggca agcggtgcga tgcccggcaa tgcgctgttt
     3181 agcgcggcca ttagcggttg gctgtggatc accgtactgt tcgctaattt cgccgaggcg
     3241 ctggcagaag gccgcagtaa agcgcaggcc aacagtctga aaggggtgaa aaaaactgcc
     3301 tttgcccgca agctgcgtga gccgaaatat ggcgctgcgg cggacaaagt tcctgccgac
     3361 caacttcgta aaggcgatat cgtactggta gaagctggcg atattatccc ctgcgatggt
     3421 gaagttattg aagggggtgc atcggtcgat gaaagcgcca tcaccgggga atcggcaccg
     3481 gtgatccgtg aatccggcgg cgattttgcc tccgtcaccg gcggcacgcg tattctttct
     3541 gactggctgg tgattgagtg tagcgttaac cccggcgaga catttctgga tcggatgatc
     3601 gcgatggtgg aaggcgcaca gcgacgcaaa acgccgaacg aaattgccct gaccattctg
     3661 ctgattgccc tgactatcgt ctttttactg gcaaccgcca cgctgtggcc gttttccgcg
     3721 tggggcggta atgcagtcag cgtaacggta ctggtggcgc tgctggtctg tctgatccca
     3781 accactattg gcggcctgtt gtcagcgatc ggcgtcgccg ggatgagccg gatgctaggc
     3841 gcgaatgtga ttgccaccag cggacgtgca gttgaagcgg caggtgacgt tgacgttctg
     3901 ctactggata aaaccggcac catcacactc ggtaaccgtc aggcgtcgga gtttatcccc
     3961 gcgcagggcg tggatgaaaa aacgctggct gacgccgcac aactggcttc gctggctgat
     4021 gaaacgccgg aaggccgcag tattgtgatc ctcgccaagc agcgttttaa cctgcgcgag
     4081 cgcgatgtgc agtcgctcca tgccaccttt gtaccgttta ctgcgcaaag ccggatgagc
     4141 gggatcaaca tcgacaaccg catgatccgt aaaggttctg tcgatgccat tcgtcgccat
     4201 gttgaggcta acggtggtca cttccctacc gatgttgatc aaaaagtcga tcaggttgcg
     4261 cgtcagggag ccacgccgct ggtggtggtg gaaggttctc gtgtgctggg cgttattgcg
     4321 ctgaaagata tcgtcaaagg cggtattaaa gagcgcttcg cccagctgcg caaaatgggc
     4381 attaaaacgg tgatgattac cggcgataac cgtctgactg ccgccgcgat tgctgcggaa
     4441 gcgggtgtcg atgattttct cgccgaagcg acaccggagg ccaagctggc attgatccgt
     4501 cagtatcagg cggaaggtcg tttggtagcg atgaccggcg acggcaccaa cgatgctccg
     4561 gcgctggcgc aggcagatgt cgcggtggcg atgaactccg gcacccaggc ggcgaaagag
     4621 gcgggcaata tggtcgatct cgactctaac ccgaccaagt tgatcgaggt ggtgcacatt
     4681 ggcaaacaga tgctgatgac ccgtggctcg ctgaccacct tcagcattgc caacgatgtg
     4741 gcgaaatact tcgccattat tccggcggca ttcgcggcaa cgtatccgca gttaaatgcg
     4801 ctgaacatca tgtgcctgca ttcgcccgac tccgcaatcc tcagtgcggt gattttcaac
     4861 gccttgatta tcgtcttttt gattcccctg gcgttaaaag gcgtgagtta taaaccgctt
     4921 accgcttctg ccatgttgcg ccgtaactta tggatttacg gtctgggtgg gctgctggtg
     4981 ccgtttatcg gtatcaaagt cattgattta ctgctgaccg tttgcggtct ggtgtgaggt
     5041 ttaccatgag tggattacgt ccggcattat caacatttat ctttctgtta ttgattactg
     5101 gcggcgttta cccgctgctg accaccgtac tggggcaatg gtggtttccc tggcaggcca
     5161 atggttcgtt gattcgtgaa ggtgatacgg tgcgcggttc ggcattaatc gggcagaatt
     5221 ttaccggcaa cggctatttt catggtcgcc cgtcggcaac ggcagaaatg ccctataatc
     5281 cacaggcttc tggcgggagc aatctggcgg tcagtaaccc tgagctggat aaactaatag
     5341 ccgcacgcgt tgctgcatta cgggccgcta acccggatgc cagcgcgagc gttccggttg
     5401 aactggtgac ggcatcggca agcgggctgg acaataatat caccccgcaa gcggcggcct
     5461 ggcaaatccc acgcgtggcg aaagcgcgta atctcagcgt tgaacagctc acgcaactga
     5521 tcgcaaaata cagccaacaa ccgctggtga aatatatcgg ccagccggtt gtcaacattg
     5581 ttgaactcaa tctggcgctg gataaacttg atgaataacg aacccttacg tcccgacccc
     5641 gatcgtctgc tggaacaaac tgccgcgccg catcggggga agctgaaagt tttcttcggt
     5701 gcctgtgcag gcgtcgggaa gacctgggcg atgctggcag aagcccagcg actgcgggcg
     5761 caagggctgg atattgtggt tggcgtggta gaaacccacg ggcgaaaaga taccgccgcc
     5821 atgctggaag ggctggctgt tctgccgtta aaacgccagg cgtaccgtgg gcggcatatc
     5881 agcgagtttg atctcgatgc cgccctcgcc cgccgcccgg cgctgatctt aatggacgaa
     5941 ctggcgcaca gtaatgcgcc aggttcccgt catcccaaac gctggcagga tatcgaagaa
     6001 ctgctggaag ctggcattga tgttttcact accgtcaacg ttcagcatct ggaaagtctg
     6061 aatgatgtgg tcagcggcgt caccggaatt caggtacggg aaaccgtgcc cgatcctttt
     6121 ttcgatgccg ccgacgacgt ggtgctggtg gacttgcccc cggacgatct gcgccagcgg
     6181 ctgaaagaag gcaaagtcta tattgccggg caggcggagc gcgccattga acattttttc
     6241 cgcaaaggta atctgatcgc cctgcgcgaa ctggcactgc gccgtactgc cgatcgcgtt
     6301 gatgagcaaa tgcgcgcctg gcgggggcat cctggcgaag agaaagtgtg gcacacgcgc
     6361 gacgcgatcc ttttatgcat cggccataac accggcagcg aaaaactggt ccgcgcagcg
     6421 gcgcggctgg cgtcacggct gggtagcgtc tggcacgcgg tgtatgttga aacccctgcc
     6481 ctgcaccgct taccggaaaa aaaacgtcgg gcaattctca gcgccttacg tctggcgcag
     6541 gaactgggcg cggagacggc aacactttct gatccagcgg aagagaaagc ggtagtgcgt
     6601 tatgcccgtg aacataatct cggcaagatt attctcggtc gcccggcctc gcgccgctgg
     6661 tggcgtcggg aaacgtttgc tgaccgactg gcgcgcatcg cccccgatct cgatcaggtg
     6721 ctggtcgcgc ttgatgaacc acccgcccgc acgattaaca acgcgccgga taaccgctct
     6781 tttaaagaca agtggcgtgt acaaattcag ggatgcgtgg ttgccgccgc gttatgcgcc
     6841 gttatcacct taattgccat gcagtggctg atggcgtttg atgccgccaa cctggtgatg
     6901 ctgtatctgc ttggcgtggt ggtggtggcg ctattttatg gacgctggcc ttcagtggtt
     6961 gccaccgtca ttaatgtagt gagtttcgat ctctttttta tcgccccacg cggcacgctc
     7021 gccgtctctg atgtgcaata tctgctgacc ttcgcggtga tgttaaccgt cgggctggtg
     7081 atcgggaacc ttactgctgg cgtgcgttat caggcgcggg tagcccgtta ccgcgagcaa
     7141 cgcacacggc acttatatga aatgtcgaaa gctctggcgg tgggccgcag tccgcaggat
     7201 atcgctgcca ccagcgaaca atttattgcc tccacgtttc atgcccgcag tcaggtgttg
     7261 ttgcccgatg acaacggtaa attgcagccg ttaacacatc cgcaaggaat gacgccgtgg
     7321 gacgatgcca tcgcgcagtg gagttttgat aaaggcctgc ctgcgggcgc gggcaccgac
     7381 acgttacccg gtgtaccgta ccagattttg ccgctaaaaa gcggcgagaa aacctacggg
     7441 ctggtggtgg tggagccggg gaatctgcgc cagttgatga tcccggaaca gcagcgcctg
     7501 ctggagacgt ttacgctgtt agtcgccaat gcccttgagc ggctgacgct aaccgccagc
     7561 gaagaacagg cgcggatggc aagcgaacgt gaacagatcc gcaacgccct gctggcggcg
     7621 ctttcgcatg atttacgcac gccgcttacg gtgctgtttg gtcaggcaga aatcttaacg
     7681 ctcgatctgg caagcgaagg atcaccccac gcccgccagg ccagcgagat ccgtcagcat
     7741 gtgctgaaca ctacccgact ggtgaataat ctactggata tggcgcgaat tcagtccggc
     7801 ggctttaatt tgaagaaaga gtggttaacg ctggaagaag tagtcggcag cgcgctgcaa
     7861 atgctggaac cgggtttatc gtcgcccatc aatctttctc tgccagaacc gctgacctta
     7921 atccacgttg acgggccact ctttgaacgg gtgctgatta atctgctgga gaacgcggtg
     7981 aaatatgcgg gtgcgcaggc cgaaattggt atcgatgccc acgttgaggg cgaaaatcta
     8041 caactggatg tctgggataa cggccccggt cttccgccag gccaggagca gacgatattt
     8101 gataagtttg ctcgcgggaa taaagagtcg gcagtaccgg gggtagggct tggactggca
     8161 atttgtcggg cgatagtgga tgtacacggg ggcactatta ccgcgttcaa ccgaccggaa
     8221 ggtggtgcct gttttcgtgt tacacttccc cagcaaactg cccctgaact tgaagaattt
     8281 catgaggata tgtgacaaac gttctgattg ttgaagatga acaggctatt cgtcgctttc
     8341 tgcgcacggc gctggagggc gacgggatgc gcgtctttga ggccgaaacg ctgcaacgcg
     8401 gcttgctgga agcggcaacc cgtaagccag atttgattat tctcgatctc ggcctgcccg
     8461 atggtgatgg gattgagttt atccgcgacc tgcgccagtg gagcgcggtg ccggtgattg
     8521 tgctttccgc acgcagcgaa gagagcgaca aaatcgccgc gctggatgcc ggagcggatg
     8581 attatctgag taagccgttt ggcattggcg aattgcaggc ccgtctgcgc gtcgcattac
     8641 gccgccactc tgccaccacc gcgcccgatc cgctggtaaa attttccgat gttaccgtcg
     8701 atttagccgc ccgcgtgatt caccggggtg aggaagaggt gcatctcaca ccaattgagt
     8761 tccgcctgct ggcggtgctg ctcaacaatg ccggaaaagt actcacccag cgccagctcc
     8821 ttaaccaggt gtgggggcca aacgcggtcg aacacagtca ctatttgcgt atttatatgg
     8881 gacatctgcg acaaaaactg gaacaggatc ccgcccgccc acgccattt
//
LOCUS       DAPHKZ010000159         8842 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.160, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000159 DAPHKZ010000000
VERSION     DAPHKZ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8842
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.160"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..846
                     /locus_tag="RH288_004099"
     CDS             <1..846
                     /locus_tag="RH288_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HDV4033095.1"
                     /translation="VFNALKLEKTKLTLVTMTMQDHATLKEIKDLAKNITQQYGTPDL
                     CIEAMRKKNLKTMIFISQLKAKTNFQVVGLTMKCYSPLCKNASRMDQNLRAPVPMTWA
                     FMMREAGFPAVRPIYELPLSEDVLDEVREEMRSLGSYIALNLEGSSQERTFSLSIAEN
                     LIAKIQSETDIPIVIVHGPKGEDKARVLVDCYNNVYRLSLSPSIKRSAAIIKDAYIAI
                     TPDTSILHMASAYNTPVVAIYADYKTRWPAMADVSESVVVGQKIDNISLDEFAKALKS
                     VLARI"
     gene            complement(1108..8184)
                     /gene="yeeJ"
                     /locus_tag="RH288_004100"
                     /pseudo
     CDS             complement(1108..8184)
                     /gene="yeeJ"
                     /locus_tag="RH288_004100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416485.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter adhesin YeeJ"
BASE COUNT         2099 a         2118 c         2143 g         2482 t
ORIGIN      
        1 gtgtttaatg cacttaaact tgaaaagact aaattaacat tagtcacaat gactatgcag
       61 gatcacgcaa cattaaaaga aataaaagat ttagcaaaga acataacaca gcaatacggt
      121 acgccggatc tttgtataga ggcgatgcgt aaaaagaacc tgaaaacgat gatatttatc
      181 agtcagttaa aagcaaaaac gaattttcag gttgttggtt taaccatgaa gtgctactcc
      241 cctttgtgca agaacgcgtc ccggatggat cagaatctcc gggctcctgt acccatgaca
      301 tgggcattta tgatgcgtga ggcgggtttt ccagcagtca ggccaatata tgaattgcca
      361 ctaagtgagg atgtactcga tgaggtgcgc gaggaaatgc gatcgttagg atcttacatt
      421 gcgcttaatt tagaaggtag ctcgcaggaa cgtacatttt cattatcgat tgcagaaaat
      481 ctaatagcaa aaattcaaag tgaaacagat ataccaatag tgatcgttca tggaccaaaa
      541 ggggaagata aagccagggt attagtggat tgttataata atgtctaccg tttatcctta
      601 tcaccctcga ttaaacgttc agcagcaatc ataaaagatg cttatatcgc aataactcct
      661 gacacctcaa tattacatat ggcaagtgcc tataatactc ccgttgttgc aatttatgct
      721 gattacaaaa cgcgatggcc cgcaatggcc gatgtttcgg agtcagtcgt cgttgggcaa
      781 aaaattgaca atataagtct ggatgaattc gcaaaggcat taaaaagtgt tttggcgaga
      841 atatgagaca gtacttatgc atagtaatgc cgatctgtta tgaacggtgg tgtcatcaat
      901 actctgaggc tggtcaatca tcacagaaaa ccagcctttg gatcaaagct gtactcaccg
      961 gatacgatca tagtcacatc gaacgcgatt cttgcggtgc agcagtttta tttattcatt
     1021 ttctgtgaga gaagggcaag ctctatagag ggaatgtaaa aaagagtgct ccgaatggag
     1081 cactctttaa gaaattataa cggaaaatca caggttttta taacatgtcg cataagcaaa
     1141 cccaagcttt tcaaatacgc tttgatcacc tgttgccagg gaaactacgt attgttcgct
     1201 tgagtttgcg ggactagatg accaatacat atttgattga aaaccagctt cagtcgtgta
     1261 atgccccata tctccccatt cactgtacag tgacccgatg cctcgggaac gactatggtt
     1321 taaatggtct gcacggggaa gtgtgtagcc attgctactg caaaaatttt cagcaaggct
     1381 gtatatcatg aaagcatcgc cggagttcac ccaccaactc ttcacacgga tttcgtatac
     1441 atagctaggg cctcctgatt ttggcgtcgc cgtaatcctt tcccaattgc tgccgacatt
     1501 tttaaatgtc actttaccgg tagcatcaac atcgacccag gaggcagagc ttgaaaactc
     1561 ataatcagcc gccgtttttc ctggggcaaa gttgtcatta ttcaactgat aatacgcccc
     1621 ggtgaacccc tgcgaaggga atgtagttgt cggtaggtca gtaccattga ctgatactgt
     1681 accgctcatt attttgtctt ctgcgcgagt gaattgtatt gtggtactca gaccagcttg
     1741 atgaacacca ttcaatacag ggatcagcgt tgcgataccc tctccgccgc ctgtaatggt
     1801 ggctttgtaa tcaccgttga tattttgact gtaatcaatt gcgctaattt tcatataggg
     1861 cacgttagta cctgattgca caaattccag cccttcagaa actttgatcg gattgcctga
     1921 tatatcgtgc agaacaagat gtagctcagc actatcggta aagtctcctt tcaatgatga
     1981 ccgattgttc ttaaggactg actttgaggc gtctgccggg ccggccacca gcgttatatc
     2041 tactgtttgc attccaccag cggtcgtgac tgcgcttacc gtgacgctcc ccgttatcgc
     2101 tcctctcacg cttgttgtcg cgattccgtt ttgatctgtc accgctgtta atgacgttaa
     2161 tgtggcagag ccgcttttta aggcgaagta cacagtgaga ccttcgatca ggttaccact
     2221 gccatcctca accgttgcct ttaaggtact taaatcactg ttggtggcgg cgatagtcga
     2281 tggatcagcg ataaagctag caacatgggc ggtgcttgag ttgccagtga ctttcacggt
     2341 tgtctgtgtc tgtattgtta cgccgttatg gaacgatgca gtcaccgtat atgtaccgac
     2401 tttattgctg gtcagaacga ctggagcctg acctgaagag ttggttccca cttttccgcc
     2461 acttaacgtc gcaccttctg gcgttacgct aaagttgatg acctgaccct ccactggagt
     2521 gccatttgca gaagttagcg ttgccgtcag agttgcacct gttggggaat tgacaccgat
     2581 aagcgggctg gacgccgaga gtgtcagttt ttaatcgatt accaccagat ccttctcata
     2641 agaggatcca ttcgccaggg atgctttcac catatacgaa ccgtttcttt cgggcgtcat
     2701 agtgacctcg gctataccat gcgtatcagt agagacaata ttttggctga tggtcatgtg
     2761 ctctggtggc tctgcactga atgttacaga ttcattaaga atcggattgc caaactggtc
     2821 gttgacgtga gctttaactg ctacgtcttg tgcgaccatg acctgacctt caggtatctc
     2881 cagactggta atcgttgcag aattaatatc tgcttttgca ttcagtaatc gcgagatgac
     2941 ttcagtaggt ttatctgcca gagaggctga aactgttttc agtccgacct cggtgcttgt
     3001 cacaagaatt tcagcgaaac cccgatcatc cgtttcaacg ctggtgctgc ttagcgtgac
     3061 ggaggttccg cggaaattaa cttttatgcc ttctaccggg ttgccgttag cgtcagtgac
     3121 gcttgcagtc atggtcgcgc cctcggtcgt gctgacgacg aaagagtata cagaggttaa
     3181 tgaggctagt tttgcggtac cagcatcggc aatcaaagtc acctgtttcg tatcactgac
     3241 accataattg ttcacgctaa ctgtcacggg gtaggtgccg gattttgtac cgctcagtgt
     3301 aacttcagcc ttgccgttga tatcagtaat ggcggaaccg ccttgtccga gagtaaagct
     3361 tgcgctcaca tctgccggta gcgtgaatgt caccgcctca ttggctaacg ggttgccgtt
     3421 tccatcagtc actgttgcct gcagcctggt catcccgacg ttattagcga taaaattgtc
     3481 ctcggtaacg ttaagattaa cctgcgcagt gagtgtatcc gcaataaagt tcaccaccaa
     3541 ctgctcactc ttaccgccag ccatcgatgc tgtaacagta tgagcgcctg cttttgtacc
     3601 tttcagcgtg actttcgctt tgccatcggc atcagtaacc gctttaccgc catcgctcag
     3661 cgtgaagttc gccctcacat cttccggcag agtaaatgtt acctcagtgt tggctatcgc
     3721 attgccctct gtatcagcga ctgttgctgt tagtgtcgtg atatcgttat tgtcggcaat
     3781 caccggatcc ttcgaggctg ccagcgtgat ttcagcattc gctacgttcg gcacataggt
     3841 cactgtttgt tgcatcgaat cgccattttc gagggttgcc gtcacttgat aaaccccggc
     3901 ttttgtagcg gtaaagcttg cgtaaaaatt gccgtcgtgg ttggtagtat atatagcgtt
     3961 attactgggg gtcacgcctt cacttggtga tactctgagg gttacctcct gctggggtac
     4021 accgttgccg taattatcct tcacctcaat atacagattg gtagtgtcgc ctgcggagac
     4081 tgtatcaaaa agtgcctgta gcaaggtgag atgtgccgta gacgcatcag cgttgacatt
     4141 aattgatgtg ctaagcgtgg agctaccatt ttccagactg gcctcaacgg tatgcggtct
     4201 cgctcctgat tctatcgagg agcgggtatt ggtataagtg acggtagcct taccctgttc
     4261 gttcgttacg gcttggccgc cattcgtcat ttcggcagag tttgttctgc tggtgaagtt
     4321 cacagtcaca cctttcaccg gaaagccatt attatcaacg actgtggcgg tgatgacgct
     4381 gccggagctg ttctgcgggg taccggcgat tatgctgtct gggacaggcg tcaactcgat
     4441 aatttttgcc gctgctgtgt cgccaataaa atgcacagtt ttgttgtcgc tggcaccatt
     4501 attagccagt gatgcagtga ccgtctgctc accaaaggca acgcctgcga gagtggcctg
     4561 cgcgatgcca gactcattgg tattacttac tcccggggtc agggtgagtc ctgaagaggc
     4621 tgagctgaat gttaccggaa gattattcac ctcattgtcg aactgatctt taaccgttgc
     4681 agttagcgtt gcgttatcga cgccattacc tgtgatctca tcttttgaca tctgcaggac
     4741 aacctgagcc gaggttttgt ccgccacaaa cgttaccggc tgcgaatcac tggtattgtt
     4801 attacccagc gttgcggtaa ccgtatgcgt acccgctttt ttacctttca gcgtgacatg
     4861 cgcttcccca ttggcttggg tgatggcaat gccgttattt tcgagggtaa agtttgccgc
     4921 aacgtcctgt ggcatggtga aggtcaccgt tattcccgcc accggatgat tcgacggatc
     4981 tttcactgtt gctgtcagag ttgtctcatc cacgccattc ccaatgattt ccgctttcga
     5041 tgtttgcaga acgacaaccg ctctgtcttt atccgccaca aacgtcattg gctgtgtatc
     5101 gctgacattg ctgttagcca gacgagccgt gatcatatgc gtgcccgcta acgtgccggt
     5161 cagggaggcg attgcaaccc cgttactatc cgtcatgcct tttcctccgt tgctaattga
     5221 gaactgactt gcgacgtcgt ttggcacaga gaaggtgatt tctttatcta ttagtgggtt
     5281 gccattttta tcctgcaagg ttgcagtcat atgtagcgga gctgtgttgg tgacggtgat
     5341 atcacctgaa ggcacactga gggtcagggc tgcagtactt tgatcaccga taaaaatcac
     5401 ctgttgatta gcctgagaac cagagctcac agaggccgta accgtataat caccattttt
     5461 caaactggtc agcgtagctg tggcgatccc gtcgtggcta ttcacttctg tttggctcag
     5521 tttcgcctct gctgaattaa cattgaaagt gaccttgacg tcattgagca ggttgccttt
     5581 tgcatcccgg actgttgcgg tcattgtggc gctatcattg ccgtcagcga ccacttcatt
     5641 tttcgacttc tgcagctcaa cctgcgcggt actcgagtcg ccgacaaaac tgacgattaa
     5701 cgtttgtttc acgccatttt caagggtgac ttcaaccgtg ttgtcttcct gcttactact
     5761 tttcagatca aaagtcgcca gaccattaac atccgttttt gcggtgtttt gattgttgaa
     5821 ggaagttgcc gatccgctta ataccgcaaa cgtgacggta tgatcattga ttgggttgct
     5881 tccttcatca gcgacattga ccgagacggt gtttgctgca ttctcattgg cgagcacacc
     5941 attattgctg gcagataatg tcgcaatttt tgctgactgc gggttggcgt cgatgataaa
     6001 accagcggta tgcaaatctt cattccagtt ttgcattaat agcttcgcag taagcccact
     6061 gcctttggta taggcggtat aggttgcctt atagacgcca tctgcggttt ctttccagtc
     6121 tgtagtgaca ccaggtttca cgttgtcgat gctgactgcg ttattcagtt gctgtttttg
     6181 ctccttaaca ggtttgtcat tttcatctct cagttctacc gtcacctcga taggattgcc
     6241 ggagagataa cggtctttat caattttaat tgacgagtga gttcgggatg acgaaataga
     6301 aatgatattc accacggcgg gggctttagc cgcatccaca ccattcagct gtggcatcag
     6361 cgtcagcgtg ccagacatcg ctcctgtggt caggatctgg gtatagcttc cgtcaccatt
     6421 atctttccat tcagaaaggg tgatgtcctg aacaccttcg tgacgcgtcg agagcaccag
     6481 cccgacaaca ggattacctg ctgcatcatg cgcaataaaa gtcagtgtgg cggttgaatg
     6541 ggaatccgcg ttcaatgttt gggtacttaa cgataccgag gaatctttct ggcttagcgt
     6601 aggtgcctga acgaccacca tgctctgttc acgattcgac aaattgcctt tgacatcttc
     6661 ggcggtgact tcaatcggcc aggtgttatc ggtttctggc gtactggtga accggtaagc
     6721 cggcagggta accagaatat ctttacccgt tgtgaccact ttgccaccgg cagcttccag
     6781 agcggtggct tcgacgttat agcctttcag ggcatatttg gtttgtagcg acgaaaccaa
     6841 tgatttcact tctcctgact tccctgtcac ggggtctgtc agggtcaggc gaaccagttc
     6901 ttttttgcgg tattccagaa cgatgttgtt gttgcgatcc accagatcat aacggctgcc
     6961 tgcaaggcta cgccgtgcag cgacttcatt cgggtcaagc tgtttctgca ttgcgctgcc
     7021 aggttgccag gtaaaatcga cggcaaaacg ggtgtcattt tcgccctgtt taccctggcg
     7081 ttgctccgcg ctgaaggtca tcagcgggaa gggggtatag ttaagtccag cggttatggc
     7141 atgaggatta ctttgccgat cgtctttatc gaacagggcc acttcatcgc cataatactg
     7201 ttcatagacc agtttaccgc caaggtacgg ccaggcgggt agccagcctt ctgcgcgtac
     7261 atcccagcca ttggccgggc gggcttcata atcgttgtcc agttcaggtg cgctgcgcca
     7321 gttggtcagt cgcaaatagc cgttactgct taattttaga tagtcgcgcc agtactccgc
     7381 gccaatgccg gcgcgggagt ggtaacggct aagatcgtgg tcgaaaaaga agttgatgcc
     7441 cgacatccat gtgggagtga aatgacgcca acctaagccg ttgttaatct gcgtacgctc
     7501 gtcagtacga tggagagtat gctgactgaa aaagagatta tcaggcgttt cataccacgg
     7561 atggagaaaa tcgaactggg agttcttcag gctaaaatct tcatccacgc ccagcgtgat
     7621 tcttgcggta ccgaagcggc ttaaccagtc tgtcattgcg cctgaagcct gagaagaggc
     7681 ccatccacgc gccatatttg ccgcttgctc gctgttcata tcttcggcga gcagagaccc
     7741 gatttgctgt gaagtactgg ctatctgttg ctcgaggttg tcactgctat tacccggcgg
     7801 cggggttaat tttttttcac taacttgtgc cgggacatcc agttcatcac cctggcggac
     7861 attatcaaaa cctcgagcaa acgtacgaaa ctggttgagt ttgcgtaact cagccaccga
     7921 aataccgaaa cgttcggcaa cgctttgggc cgattccagc gctccaaggg tgtagggcac
     7981 cgtattggca tttgcaatgg caatttgtgc aggaactggt tgttgggttg cggcgtttac
     8041 cacaccttgt gctgccgcag ccatagggaa cgcaagttga gttatcagac agatacccgc
     8101 agttaagcgg cgtagtttaa ttcccatccc gcataagatt tgtcggtcat ttattttttc
     8161 tccacttctc ttcttcgtag ccatgcttac cttccctgaa cgagctaaca taaatgcgcc
     8221 ctttctagca cagcgaaaaa atgtaaatcc tgatagcaat atgattgaaa attaataact
     8281 tttcgttagg cagttttggg tgtgagttgc aagaggggag actactgaat aactcaagtt
     8341 ttataatcga ggggaaaatg gtgatggcgc catagcaaaa cgccctcaac cataaaggtc
     8401 gagggcgctt aagatgttaa aaacccgcta tccgttaaaa aacaatgttc aactaaggtc
     8461 agtgacattg cgctaaaaaa gcgaattttt agaatttggc tcctctgact gggatcgccg
     8521 tagccaataa atagctgatt ggtaagctaa aaaaaatcga gtttgtcaag accaccaggc
     8581 tgaccacctt ttgttcgagc gacacggaga cttcagttga gtacagaata gttccttgcc
     8641 accgggttcg atctggctga gctattggga ctgactcagc acttcacggc ctgacacagt
     8701 tgaccgcaag tccctgcaca ccggaaaaag tcagcgcaat ctacacctgg tcgtctcccc
     8761 cggagtctta cgttgtaccg atattaggca ctatttagct tgccgccttc ccgcaactcg
     8821 aactatttaa tcaattaacg ga
//
LOCUS       DAPHKZ010000160         8832 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.161, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000160 DAPHKZ010000000
VERSION     DAPHKZ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8832
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.161"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..827
                     /locus_tag="RH288_004101"
     CDS             <1..827
                     /locus_tag="RH288_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDV4033096.1"
                     /translation="YGKDTSKEERLKKLYTELISDLLSHSIGCQMGRYSLDREGLVYA
                     HEGNKGFADLVAEGAYKTFPADSDGILPLMDDEWFEDDVTSRVKEFVRTVWGEEHLQE
                     NLEFIAESLCLYAIKPKKGESALETIRRYLSTQFWKDHMKMYKKRPIYWLFSSGKEKA
                     FECLVYLHRYNDATLSRMRTEYVVPLLARYQANIDRLNDQLDEASGGEATRLKRERDS
                     LIKKFSELRSYDDRLRHYADMRISIDLDDGVKVNYGKFGDLLADVKAITGNAPEVI"
     gene            1004..3601
                     /gene="pglZ"
                     /locus_tag="RH288_004102"
     CDS             1004..3601
                     /gene="pglZ"
                     /locus_tag="RH288_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HDV4033097.1"
                     /translation="MQNQDFIAGLKAKFAEHRIVFWHDPDKRFIEELEQLKLENVTLI
                     NMTHASQLAVKKRIEMDEPEQQFLLWFPHDAPPHEQDWLLDIRLYSSEFHADFAAITL
                     NTLGIPQLGLREHIQRRKAFFSNKRTQALKNLVTEQEDEASLDKKMIAVIAGAKTAKT
                     EDILFNLITQYVNQQTEDDSELENTQAMLKRHGLDPVLWEMLNHEMGYQAEEPSLENL
                     LLKLFCTDLSAQADPQQRAWLEKNVLLTPSGRASALAFMVTWRADRRYKEAYDYCAQQ
                     MQAALRPEDHYRLSSPYDLHECETTLSIEQTIIHALVTQLLEESTTLDREAFKKLLSE
                     RQSKYWCQTQPEYYAIYDALRQAERLLNLRNRHIDGFHYQDSATFWKAYCEELFRFDQ
                     AYRLFNEYALLVHSKGAMILKSLDDYIEALYSNWYLAELSRNWNEVLEAENRMQAWQI
                     PGVPRQQNFFNEVVKPQFQNPQIKRVFVIISDALRYEVAEELGNQINTEKRFTAELRS
                     QLGVLPSYTQLGMAALLPHEQLCYQPSNGDIVYADGLSTSGIPNRDTILKNYKGMAIK
                     SKDLLELKNQEGRDLIRDYEVVYIWHNTIDATGDTASTEDKTFEACRTAVTELKDLVT
                     KVINRLHGTRIFVTADHGFLFQQQALSVQDKTTLQIKPENTIKNHKRFIIGHQLPADD
                     FCWKGKVADTAGVSDNSEFLIPKGIQRFHFSGGARFVHGGTMLQEVCVPVLQIKALQK
                     TAVEKQPQRRPVDIVAYHPMIKLVNNIDKVSLLQTHPVGELYEPRILNIYIVDNANNV
                     VSGKERISFDSDNSTMEKRVREVTLKLIGANFNRRNEYWLILEDAQTETGYQKYPVII
                     DLAFQDDFF"
     gene            3612..5696
                     /gene="brxL"
                     /locus_tag="RH288_004103"
     CDS             3612..5696
                     /gene="brxL"
                     /locus_tag="RH288_004103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HDV4033098.1"
                     /translation="MQAHHDLPVSGVSAGEIASEGYDLDALLNQHFAGRVVRKDLTKQ
                     LKEGANVPVYVLEYLLGMYCASDDDDVVEQGLQNVKRILADNYVRPDEAEKVKSLIRE
                     RGSYKIIDKVSVKLNQKKDVYEAQLSNLGIKDALVPSQMVKDNEKLLTGGIWCMITVN
                     YFFEEGQKTSPFSLMTLKPIQMPNMDMEEVFDARKHFNRDQWIDVLLRSVGMEPANIE
                     QRTKWHLITRMIPFVENNYNVCELGPRGTGKSHVYKECSPNSLLVSGGQTTVANLFYN
                     MASRQIGLVGMWDVVAFDEVAGITFKDKDGVQIMKDYMASGSFSRGRDSIEGKASMVF
                     VGNINQSVETLVKTSHLLAPFPAAMIDTAFFDRFHAYIPGWEIPKMRPEFFTNRYGLI
                     TDYLAEYMREMRKRSFSDAIDKFFKLGNNLNQRDVIAVRRTVSGLLKLMHPDGAYSKE
                     DVRVCLTYAMEVRRRVKEQLKKLGGLEFFDVNFSYIDNETLEEFFVSVPEQGGSELIP
                     AGMPKPGVVHLVTQAESGMTGLYRFETQMTAGNGKHSVSGLGSNTSAKEAIRVGFDYF
                     KGNLNRVSAAAKFSDHEYHLHVVELHNTGPSTATSLAALIALCSILLAKPVQEQMVVL
                     GSMTLGGVINPVQDLAASLQLAFDSGAKRVLLPMSSAMDIPTVPAELFTKFQVSFYSD
                     PVDAVYKALGVN"
     gene            complement(5961..6386)
                     /locus_tag="RH288_004104"
     CDS             complement(5961..6386)
                     /locus_tag="RH288_004104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033099.1"
                     /translation="MNGLKTGLGITPGEHIISADSALSRNIRHCFCLSCRGRLILQTD
                     AQGAWFEHDLHALTAQQKTDCVVLNPEKSHPYIDDMAMFLSPLPVVLEWHCVMCGQHF
                     PGKKFCEACGTGIYSRAVCTKYVYSYQPDLFLDCGSAST"
     gene            complement(6383..6766)
                     /locus_tag="RH288_004105"
     CDS             complement(6383..6766)
                     /locus_tag="RH288_004105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033100.1"
                     /translation="MYAKSFLAFDGNGRLTGARTAQTAPYDRYTCHLCGSALRYHPQY
                     DTERPWFEHTGEGLAEHGHECPYVRPERREILLIKRLQQWVPDALPVVRKTSWHCRQC
                     HHDYYGEQYCTHCHTGRFSEEAVAG"
     gene            complement(7148..7747)
                     /locus_tag="RH288_004106"
     CDS             complement(7148..7747)
                     /locus_tag="RH288_004106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HDV4033101.1"
                     /translation="MKTYNANPGYEMDPQLLTHFNQHLDSLFGVYSKLLPFRMDFAYR
                     KNTFSYGCACRYAMCAEMLQLINEVGEKLVGYAWVMEYTERKGLHIHFVGYLNGQIHR
                     SSYLVSRLMGDIWRRVTDGNGYYHWCRFNKNYPVNINHVIHYSDHKAVNALRYAISYL
                     AKREQKECGIVLGCSRLPEKSHRGRPRLDSTLPGICSQV"
     gene            complement(7979..8191)
                     /gene="hha"
                     /locus_tag="RH288_004107"
     CDS             complement(7979..8191)
                     /gene="hha"
                     /locus_tag="RH288_004107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HDV4033102.1"
                     /translation="MEVKTKEDWLYQFRRCLSRETLEKVISHTRYKLTPAELEAFNSA
                     VDHRLAELTMNKLYDRVPASVWKYVT"
BASE COUNT         2358 a         2174 c         2181 g         2119 t
ORIGIN      
        1 aatatggcaa agatacttca aaagaagaaa gattaaaaaa attatatact gaattaataa
       61 gtgatttgtt aagtcattct atcggctgcc aaatgggacg ctattccctc gatcgcgaag
      121 gccttgtcta cgcccatgaa ggtaacaaag gcttcgccga tctcgtcgcc gaaggtgcgt
      181 acaaaacctt cccggccgac agtgacggca tcctgccgct gatggatgac gagtggtttg
      241 aggacgacgt cacctctcgc gtcaaagagt ttgtccgcac cgtctggggc gaagagcacc
      301 tgcaggaaaa cctcgaattt atcgccgaaa gtctctgttt atacgcgatc aagccgaaaa
      361 aaggcgaatc tgcgctggag accattcgtc gctatctttc cacccagttc tggaaagatc
      421 atatgaagat gtataaaaag cgcccaatct actggctatt cagctccggc aaagagaaag
      481 cctttgagtg cctggtgtat ctgcatcgct ataacgatgc cacgctgtcg agaatgcgta
      541 ccgaatatgt ggtgccgctg ctggcgcgtt atcaggccaa tatcgatcgc ctgaacgatc
      601 aacttgatga ggcttctggc ggtgaagcta ctcgcctgaa acgcgaacgc gacagcctga
      661 tcaaaaaatt cagcgaactg cgcagctatg acgaccgcct gcgtcactat gctgatatga
      721 gaatcagtat tgatctcgac gatggcgtta aggttaacta cggcaagttt ggcgatctgc
      781 tggcagatgt caaagccatc accggcaatg ccccagaggt gatctaaacc agacggcgcg
      841 ttctcctgct gccgggttct gcccggtggc aaataccacc gggaaacgcg ccgctgctgg
      901 catttctcca cctcacttca tgataaaatg cgccatcgtg tcaaaatctc cttttcacgt
      961 tttggcgctt tcttattcat cgtaacaaca tgggattgtg aacttgcaaa atcaggactt
     1021 tattgctggc cttaaagcta aatttgccga acatcgcatc gttttctggc acgatcccga
     1081 taaacgtttt attgaggaac tggaacagct caagcttgaa aacgtcacgc taatcaacat
     1141 gacccacgcg tcacagctgg cggtgaaaaa acgcatcgag atggatgaac cagaacagca
     1201 gttcctgctg tggtttcctc atgatgcgcc gcctcatgaa caagactggc tgctggatat
     1261 ccgcctttac agcagcgaat tccatgccga ttttgccgct atcaccctaa acacgctggg
     1321 cattccgcag cttggcctgc gcgagcatat tcagcgacgc aaggccttct tcagcaataa
     1381 acgcacgcag gcgctgaaaa acctggtgac agaacaggaa gatgaagcct cgctggataa
     1441 gaaaatgatt gcggtgatcg ctggcgcaaa gaccgcgaaa accgaagaca ttttgttcaa
     1501 tctgattacc cagtacgtta accaacaaac agaagacgac agcgaactgg aaaacacgca
     1561 ggcgatgctg aaacgccacg gtctggaccc ggtattgtgg gaaatgctca accacgaaat
     1621 gggctaccag gcagaggagc catcgctgga aaacctgctc ctgaaactgt tttgtaccga
     1681 tctctctgcc caggccgacc cacagcaacg cgcctggctg gaaaaaaatg tcctgctaac
     1741 gccatccggc agagcatctg ccctggcatt tatggtgacc tggcgtgccg atcgtcgcta
     1801 taaagaggct tatgactact gcgctcagca aatgcaggcc gccctgcgcc cggaagatca
     1861 ttaccgactc agctcgccgt atgatttgca cgaatgcgaa accaccctca gcatcgaaca
     1921 aaccattatt catgcgctgg taacgcagct gctggaagag agcaccacgc tcgataggga
     1981 agcctttaaa aaactgctct ctgagcgcca gagcaaatac tggtgtcaga cacaaccaga
     2041 gtattacgcc atctatgacg cactgcgcca ggctgagcgt ttgctgaacc tgcgcaatcg
     2101 ccacatcgat ggtttccact accaggacag cgccaccttc tggaaagcct actgcgaaga
     2161 actgttccgc ttcgaccagg cttatcgcct gtttaatgaa tatgccctgc tggttcacag
     2221 caaaggggcg atgatcctca agagcctgga tgattatatc gaggcgctct acagcaactg
     2281 gtatctggca gaattaagcc gtaactggaa cgaagtgctg gaagcggaaa atcgtatgca
     2341 ggcgtggcaa atccccggtg tgccgcgtca gcagaacttt ttcaatgagg tggtgaagcc
     2401 gcagttccaa aatccgcaaa tcaaacgcgt gttcgtgata atttccgatg ccctgcgtta
     2461 tgaagtggcg gaggagctgg ggaatcaaat caataccgag aaacgcttta ccgcagaact
     2521 gcgctcgcag ctcggcgtgc tccccagcta cacccaactg ggaatggcgg cgttgctgcc
     2581 ccatgaacaa ctttgctatc aaccaagtaa cggcgacatc gtttatgctg atgggctgtc
     2641 gacctcgggt attcctaacc gcgataccat tctgaagaac tataagggaa tggcgataaa
     2701 atcgaaggac cttctggagt taaaaaatca ggaagggcgg gaccttattc gcgattacga
     2761 agtggtgtat atctggcata acacgattga tgccaccggt gacacggcat ccacggaaga
     2821 taaaaccttc gaagcgtgcc gcacggcggt gactgaactg aaagatttag tcaccaaggt
     2881 aatcaaccgt ctccacggca cacgcatttt tgttacggcg gatcacggtt tcctgttcca
     2941 gcaacaggcg ctttcggttc aggataaaac cactctgcaa attaagccgg aaaacaccat
     3001 caagaaccac aaacgcttta ttatcggcca tcagcttccc gccgatgatt tttgctggaa
     3061 aggtaaagtg gcagataccg caggcgtgag cgacaacagc gagttcctta ttccgaaagg
     3121 gatccagcgc ttccatttct ctggcggcgc gcgcttcgtt catggcggca ccatgttgca
     3181 ggaggtttgc gttccggtat tgcagataaa agccctgcaa aaaaccgccg tagaaaaaca
     3241 gccgcagcgc cgcccagtgg atattgtcgc ttaccatccg atgattaagc tggtgaacaa
     3301 tatcgataaa gtgagcctgt tgcagacgca tccggtgggc gaactttatg aaccgcgtat
     3361 cctgaacatt tacattgtcg acaacgccaa caatgtggtc tcgggcaaag agcgcatcag
     3421 ctttgacagt gataacagca ccatggaaaa acgcgtacgc gaagttacgc tgaagctgat
     3481 tggcgctaac ttcaaccgtc gcaatgagta ctggttgata ctggaagacg cacaaacgga
     3541 aacggggtat cagaagtacc cggtcattat cgatctggcg ttccaggatg atttcttcta
     3601 agtgaggcga tatgcaagcc catcatgatt tacctgtttc aggcgtatcc gcaggggaaa
     3661 ttgcctccga gggttacgat ctggacgccc tgctgaacca gcattttgct ggtcgtgtgg
     3721 tgcgtaaaga tctcaccaag caactcaagg aaggggcaaa cgtcccggtg tatgtgctgg
     3781 agtatctgct cggcatgtac tgcgcctctg acgatgacga cgtggtcgag caagggttgc
     3841 aaaacgttaa gcgtattctg gctgataact atgtgcgccc ggatgaagca gagaaagtga
     3901 agtcgctgat ccgcgagcgt ggttcgtaca aaatcatcga taaagtgtcg gtgaagctaa
     3961 accagaaaaa agacgtttac gaagcccagc tttctaacct cggcatcaaa gacgcgctgg
     4021 tgccatcgca gatggttaaa gacaacgaga agctactgac gggcggtatc tggtgcatga
     4081 ttaccgttaa ctatttcttt gaagaagggc agaagacttc gcccttctca ttgatgacgc
     4141 ttaagcctat ccagatgccg aatatggata tggaagaagt gttcgatgcg cgtaaacact
     4201 ttaaccgtga ccagtggatc gatgtgctgc tgcgctcggt gggtatggag cccgccaata
     4261 ttgagcaacg caccaaatgg caccttatca cccgtatgat cccgttcgtg gagaacaact
     4321 ataacgtttg cgagctgggg ccgcgtggca ccggtaaaag ccatgtgtat aaagagtgtt
     4381 ctcctaactc cctgttagtt tctggcgggc aaacgaccgt tgccaacctg ttctacaaca
     4441 tggccagtcg ccagatcggc cttgttggca tgtgggatgt ggtagcgttt gacgaagtcg
     4501 cggggatcac tttcaaagat aaagacggcg tgcaaatcat gaaagattac atggcgtcag
     4561 gatctttctc tcgcggcaga gattcgattg aaggtaaagc gtcgatggtt ttcgtcggca
     4621 acatcaatca aagcgtagag actctcgtta aaaccagcca tttgctggcg ccatttccgg
     4681 ctgcgatgat tgatactgca tttttcgacc gctttcatgc ctatattccc ggttgggaaa
     4741 tccccaaaat gcgcccggaa ttttttacca accgttacgg gctgattacg gattatctcg
     4801 ctgaatatat gcgcgaaatg cgcaaacgca gtttctctga tgcgattgat aaattcttta
     4861 agctgggtaa caacctcaac cagcgtgacg ttattgccgt tcgacgtacc gtgtcggggt
     4921 tgttaaaact catgcatccc gatggcgcgt acagcaaaga agatgtgcga gtctgcctga
     4981 cctatgcgat ggaagttcgt cgccgcgtga aagagcaact taaaaaactg ggcggtctgg
     5041 agttcttcga tgtgaacttt agctacatcg acaacgaaac gctggaagag ttttttgtaa
     5101 gcgtaccgga acagggcggc agcgaactta ttcctgccgg aatgccaaag ccgggtgttg
     5161 tgcatctggt cactcaggca gaaagcggca tgaccgggct gtatcgtttt gaaacacaga
     5221 tgactgccgg taatggtaag catagtgtat cgggtctggg ttcaaatacc tccgcgaaag
     5281 aagctatccg cgtcggtttc gattacttca aaggcaattt gaatcgggta agcgcggccg
     5341 cgaaattctc cgatcatgaa tatcaccttc atgtcgttga actgcataat actggcccaa
     5401 gcaccgcaac cagtcttgct gcgcttatcg ctttatgttc gatattgctg gcaaaaccgg
     5461 tgcaggaaca gatggtggtg ttgggcagta tgacgcttgg tggggtaatt aacccggtgc
     5521 aggatcttgc cgccagttta cagctcgcct tcgacagcgg tgcaaaacgg gttctgttgc
     5581 cgatgtcctc ggctatggat attccaacgg ttccggcaga gttatttacc aagtttcagg
     5641 tgagttttta ctcagacccg gttgatgctg tttataaggc gctgggtgtg aattaacgta
     5701 gtaactattt taatgaactg gagaggacaa tggctcaaga acgttctgta attaaattca
     5761 tcagaccttg cctctccatt catgaatata aaaatactta catctgagta ttgttggctg
     5821 tgtttgaata aaaagagagc tgttcaaata agcctgtata actgttcttt acaaaaaatg
     5881 gaggggctat cagctaattc aacactggaa gatgttcgtc gagttggatt gaacgccctg
     5941 cgcagaccgg gcatttcgga ttaagtgctc gcacttccac agtccaggaa caagtctggc
     6001 tggtagctgt aaacatactt tgtacatacc gctctggaat agatccccgt gccacaggct
     6061 tcacagaact ttttcccggg aaaatgctgc ccgcacatca cacaatgcca ctccagcacg
     6121 acaggtaatg gcgataaaaa catcgccata tcatcaatgt aaggatggga tttttccgga
     6181 ttcagcacca cgcagtccgt cttctgttgc gcggtcaggg catgtaaatc gtgctcaaac
     6241 cacgccccct gagcatctgt ctgcaaaatc aaccgaccac gacaggaaag gcagaaacaa
     6301 tgcctgatat ttctgctgag cgcagaatcg gcactgataa tgtgctcacc tggcgtgatc
     6361 cccagccccg tttttagacc gttcatcctg ccactgcctc ctcactgaaa cgccctgtat
     6421 gacagtgtgt gcagtactgc tccccataat aatcgtggtg acattgtctg cagtgccagc
     6481 tggttttacg caccacgggt aaggcatccg gtacccattg ctgtaagcgt ttaatcaaca
     6541 gtatttctct gcgctccggt ctgacataag ggcactcatg accgtgctca gccagccctt
     6601 cgccagtgtg ttcaaaccag ggacgttcgg tatcgtattg cgggtggtat ctgagcgcac
     6661 tgccgcaaag gtgacaggtg tatcgatcgt aaggcgctgt ctgtgcagta cgggcaccgg
     6721 tcaggcgtcc gttgccatcg aatgcgagaa aagattttgc gtacatcgtc atattcctca
     6781 gccgccagac gacacgcagg cagcaaccgt cccggtacgg gcagcgtggt cagggtgtga
     6841 atggcggttc agttaaaaat ctggaatggg ggtgaggtaa aacaggcagg ctgctgttac
     6901 agcactgtgg ttgtcacaca atggcccacc gacgtaaaaa actgtctgca agcagagatg
     6961 gacatccagc gcatgcagca ccgttgcagc catcaggggt tttactggtg tgtcatgtat
     7021 ggttaagttt ccgtatagtt tcgttcatac ggagtaacca catcgtaaaa aatgcacagt
     7081 gcctctgaag tggcctccgg aaccgactgc aaagattaga gccagtccgc agttctcgct
     7141 cagaacctta tacctgagaa catatccccg gcagggtgct gtccagtcgc ggtcgccccc
     7201 ggtgactttt ttcaggaagc ctgctgcaac caagaacgat gccacattct ttctgttctc
     7261 gtttggcaag gtagctaatg gcatagcgta aagcattcac cgctttgtgg tctgaatagt
     7321 gaatgacgtg attaatgttt accggataat ttttattaaa ccggcaccag tggtagtaac
     7381 cattaccatc ggtaacccgc ctccagatat ctcccatcaa tctggatacc agatacgaac
     7441 tcctgtggat ctgaccgttc agatagccca caaaatgaat gtgaagccct ttacgttctg
     7501 tatattccat cacccaggca tacccgacca gtttctctcc cacctcgtta atcagttgca
     7561 gcatctccgc gcacatggcg tacctgcagg cgcatccgta gctgaatgtg ttttttcggt
     7621 aagcaaaatc cattctgaac ggtaacagct tcgaatagac cccgaataat gaatccagat
     7681 gctggttaaa gtgtgtcagg agctggggat ccatttcgta accgggattg gcgttgtaag
     7741 tcttcatgtt tcttcctcgt gttctgtaac acaagaagaa gcgctggcgt aatttttgaa
     7801 gaaaacgtta tcacacgaag acgtgcaagt tcacaactcc ccgggcgcca cagagaaagt
     7861 gggagcacac ccgggtatca gaaccataca gagaacggca tacgtgactg tcaatcacag
     7921 cgcagataat atctgatatg atgtcattgt gacgactgta cttcatcaga aacatttatc
     7981 aggtaacata tttccagact gaagcgggaa cacgatcgta aagtttgttc atggtcagtt
     8041 ctgccagccg gtgatcgacc gcagagttga aagcttccag ctccgcaggg gtaagtttat
     8101 aacgcgtgtg ggaaatcact ttttccagtg tctcccggga taaacaacga cgaaactgat
     8161 atagccagtc ttctttggtc ttaacttcca ttatcctctc gttattttgt gctgtgatta
     8221 acgttaacat aataccgtta gaataacgta ttctgacgtc atcccggaag tctttccact
     8281 ttcctgtctc tccggtaata aaacatttta aatgctgaag gcataacgcc ataaccagat
     8341 attacaagta acgtggcgtt acacgtgtta atgcattaca gaagtaacag agacaatcag
     8401 atagtaaaca acactccgga agactgttta atggcataag gtatactttt ttacgagtaa
     8461 gattatgtat taccactaat actcatcagg tgagttgcaa gagcagatca ttaacagtaa
     8521 atccctcaat cagcattatc cacagtattg agactggcga agtcatactc ttacctcgcc
     8581 agaaatgctt acacaaacac acaaaagcaa tggaggaccc agaatagcct ccacacaaca
     8641 ggcattactt aacaaagtac attacagtca gagtgtctac attacagatt tatattcagg
     8701 tgttacgagg ttacattaca gcagagagtt aaggacagag ttacaagtac tactacagag
     8761 aatatctctg tacagatact tctatgagca tatctttaag agagatccgt ctacaggatt
     8821 gggttacaag gt
//
LOCUS       DAPHKZ010000161         8790 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.162, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000161 DAPHKZ010000000
VERSION     DAPHKZ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8790
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.162"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(55..801)
                     /gene="dsbG"
                     /locus_tag="RH288_004108"
     CDS             complement(55..801)
                     /gene="dsbG"
                     /locus_tag="RH288_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HDV4033103.1"
                     /translation="MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQQYEASGGKLKLNVPANVSTEQMKVLSDNEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMGNK"
     gene            1173..1736
                     /gene="ahpC"
                     /locus_tag="RH288_004109"
     CDS             1173..1736
                     /gene="ahpC"
                     /locus_tag="RH288_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HDV4033104.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            1981..3546
                     /gene="ahpF"
                     /locus_tag="RH288_004110"
     CDS             1981..3546
                     /gene="ahpF"
                     /locus_tag="RH288_004110"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDV4033105.1"
                     /translation="MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQ
                     NEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIV
                     GSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVH
                     VDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIG
                     LLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKTA"
     gene            complement(3667..4095)
                     /gene="uspG"
                     /locus_tag="RH288_004111"
     CDS             complement(3667..4095)
                     /gene="uspG"
                     /locus_tag="RH288_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HDV4033106.1"
                     /translation="MYKTIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAQERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAE
                     ELGADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     gene            4316..5554
                     /locus_tag="RH288_004112"
     CDS             4316..5554
                     /locus_tag="RH288_004112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
                     /protein_id="HDV4033107.1"
                     /translation="MKALTYHGPHHVQVENVPDPGVEQADDIILRITATAICGSDLHL
                     YRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGDRVVIPFVIACGDCFFCRLQQYA
                     ACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
                     SDDKALFLSDILPTAWQAAKNAQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVD
                     HHPYRLHFAADRYGAIPINFDEDSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTET
                     VLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFGDAFDKGLSFKMGQT
                     HVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQS
                     AEAAQKAVSGLVNAMPGGTI"
     gene            complement(5785..6195)
                     /gene="rnk"
                     /locus_tag="RH288_004113"
     CDS             complement(5785..6195)
                     /gene="rnk"
                     /locus_tag="RH288_004113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HDV4033108.1"
                     /translation="MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMC
                     SPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLR
                     VGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL"
     gene            complement(6425..7231)
                     /gene="rna"
                     /locus_tag="RH288_004114"
     CDS             complement(6425..7231)
                     /gene="rna"
                     /locus_tag="RH288_004114"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HDV4033109.1"
                     /translation="MKAFWRNAALLAVSLLPFSSANALALQAKQYGDFDRYVLALSWQ
                     TGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFG
                     CATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
                     GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKL
                     TCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKAGY"
     gene            complement(7345..>8790)
                     /gene="citT"
                     /locus_tag="RH288_004115"
     CDS             complement(7345..>8790)
                     /gene="citT"
                     /locus_tag="RH288_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/succinate antiporter CitT"
                     /protein_id="HDV4033110.1"
                     /translation="NIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAMIVGMIL
                     EPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSSTTVWLVF
                     GAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNTARTGGT
                     VFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVLGLEFVS
                     KIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDELKTMGA
                     LTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITRYNSAWN
                     TLVNLATLVVMANGLTRSGFIDWFAGTMSTHLEGFSPNATVIVLVLVFYFAHYLFASL
                     SAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIYGCGYVK
                     SKDYWRLGAIFGVIYISMLLLVGWPILAMWN"
BASE COUNT         2276 a         2159 c         2233 g         2122 t
ORIGIN      
        1 tttttaggat ggttgaaaag cagggatata gttcaaccat ccatgaatta ccttttattt
       61 attccccata atgatattaa gcgttttctg atcgggcaac cccacggcct gttgtagcgt
      121 attttcctta ctcatgtaat agatagccgg cgtgacattt gcccccagat cgtccatcag
      181 tttctcattg tcacttaaca ctttcatttg ctctgtactt acgtttgcag gcacgtttag
      241 cttaagcttg ccaccagagg cttcatattg ttgccaggtt tttgcgggat ctttggaggc
      301 aagaattgcc gctgctgtcg ccgggctttc tggcttgata accccaacca acaatgttct
      361 taattgcact ttgccagaat ctacccacgg gcgcgcctgc tgccagaact gtttacaata
      421 tgggcagaac ggatcggcga agacgtagac aatgaccggc gcatcttttt taccgtcgag
      481 gagccagtgg gattgttcca tccgttgcca catttcgcgt ccggctggtg cgtaaatttc
      541 tttttcgata agtgtgttac tcaggttttc acctttctcg ttgtacatgt aaccagagat
      601 agcgtgctta ccatctggag tcaggtagat ggtgacgccc atatcctgat actttccgag
      661 ataacctttc attcctccgg gggcatcgaa tgttttgatg attgtaatgc cctgtttttc
      721 aatcgctttt actggagcag gaagttcctc tgcgaaggcg attgcaggaa gcagagccag
      781 taaaagtatc ttttttaaca ttaatttgtc cttttcagtc agtgcaaaag tcgagtaaaa
      841 ggcataacct atcactgtca taggtaagag cttagatcag gtgattgccc tttgtttatg
      901 agggtgttgt aatccatgtc gttgttgcat ttgtaagggc aacacctcag cctgcaggca
      961 ggcactgaag ataccaaagg gtagttcaga ttacacggtc acctggaaag ggggccattt
     1021 tactttttat cgccgctggc ggtgcaaagt tcacaaagtt gtcttacgaa ggttgtaagg
     1081 taaaacttat cgatttgata atggaaacgc attagccgaa tcggcaaaaa ttggttacct
     1141 tacatctcat cgaaaacacg gaggaagtat tgatgtcctt gattaacacc aaaattaaac
     1201 cttttaaaaa ccaggcattc aaaaacggcg aattcatcga aatcaccgaa aaagataccg
     1261 aaggccgctg gagcgtcttc ttcttctacc cggctgactt tactttcgta tgcccgaccg
     1321 aactgggtga cgttgctgac cactacgaag aactgcagaa actgggcgta gacgtatacg
     1381 cagtatctac cgatactcac ttcacccaca aagcatggca cagcagctct gaaaccatcg
     1441 ctaaaatcaa atatgcgatg atcggcgacc cgactggcgc cctgacccgt aacttcgaca
     1501 acatgcgtga agatgaaggt ctggctgacc gtgcgacctt cgttgttgac ccgcagggta
     1561 tcatccaggc aatcgaagtt accgctgaag gcattggccg tgacgcgtct gacctgctgc
     1621 gtaaaatcaa agcagcacag tacgtagctt ctcacccagg tgaagtttgc ccggctaaat
     1681 ggaaagaagg tgaagcaact ctggctccgt ctctggacct ggttggtaaa atctaaattt
     1741 ccttcgtctt tcacgccata gcggcgttgg cgtcgcccgc tcaccccggt cacttacttg
     1801 tgtaagctcc cggggattca caggctagcc gccttgctct gacgcgaaat acttcggaaa
     1861 ttcacctaat tcttcgggtg ctgcggcacc cgattttctt ccccgcacca tgatgcaagc
     1921 tgcatccagg tagccgcaga ggccgcttgc atgatgatgt ttaaagccca ggagataaac
     1981 atgctcgaca caaatatgaa aactcaactc aaggcttacc ttgagaaatt gaccaagcct
     2041 gttgagttaa ttgccacgct ggatgacagc gctaaatcgg cagaaatcaa ggaactgttg
     2101 gctgaaatcg cagaactgtc agacaaagtc acctttaaag aagataacag cttgccggtg
     2161 cgtaagccgt ctttcctgat caccaaccca ggttccaacc aggggccacg ttttgcaggc
     2221 tccccgctgg gccacgagtt cacctcgctg gtactggcgt tgctgtggac cggtggtcat
     2281 ccgtcgaaag aagcgcagtc tctgctggag cagattcgcc atattgacgg tgattttgaa
     2341 ttcgaaacct attactcgct ctcttgccac aactgcccgg acgtggtgca ggcgctgaac
     2401 ctgatgagcg tactgaaccc gcgcatcaag cacactgcaa ttgacggcgg caccttccag
     2461 aacgaaatca ccgatcgcaa cgtgatgggc gttccggcag tgttcgtaaa cgggaaagag
     2521 tttggtcagg gccgcatgac gttgactgaa atcgttgcca aaattgatac tggcgcggaa
     2581 aaacgtgcgg cagaagagct gaacaagcgt gatgcttatg acgtattaat cgtcggttcc
     2641 ggcccggcgg gtgcagcggc agcaatttac tccgcacgta aaggcatccg taccggtctg
     2701 atgggcgaac gttttggtgg tcagatcctc gataccgttg atatcgaaaa ctacatttct
     2761 gtaccgaaga ctgaagggca gaagctggca ggcgcactga aagttcacgt tgatgaatac
     2821 gacgttgatg tgatcgacag ccagagcgcc agcaaactga tcccagcagc agttgaaggt
     2881 ggtctgcatc agattgaaac agcttctggc gcggtactga aagcacgcag cattatcgtg
     2941 gcgaccggtg caaaatggcg caacatgaac gttccgggcg aagatcagta tcgcaccaaa
     3001 ggcgtgacct actgcccgca ctgcgacggc ccgctgttta aaggtaaacg cgtagcggtt
     3061 atcggcggcg gtaactccgg cgtggaagcg gcaattgacc tggcgggtat cgttgagcac
     3121 gtaacgctgc tggaatttgc gccagaaatg aaagccgacc aggttctgca ggacaaactg
     3181 cgcagcctga aaaacgtcga cattattctg aatgcgcaaa ccacggaagt gaaaggcgac
     3241 ggcagcaaag tcgttggtct ggaatatcga gatcgtgtca gcggcgatat tcacaacatc
     3301 gaactggccg gtattttcgt ccagattggt ctgctgccga acaccaactg gctcgaaggc
     3361 gcagtcgaac gtaaccgcat gggcgagatt atcattgatg cgaaatgcga aaccaacgtg
     3421 aaaggcgtgt tcgcagcggg tgactgtacg acggttccgt acaagcagat catcatcgcc
     3481 actggcgaag gtgccaaagc ctctctgagt gcttttgact acctgattcg caccaaaact
     3541 gcataagaag aagtaagatt cacctgcaat tgcttagccg ccggggtcaa acctggcggc
     3601 ttttttatgg cattaaaaag ccccgccggg atggctccgg gcagggcggg atacttattc
     3661 tggcaattaa cgcacaacca gcaccggcag attggcgtgg cggatcacgc tcgaggcgtt
     3721 agaacctaac agatgggtcg aaatcgatgg gttgcgagaa ccaataacta caacatcagc
     3781 ccccagttct tctgccaact cattgacttc atcccgcacg ctaccaaaac ggacatgttg
     3841 tttaatgcgg gaaggatcga tggtgaagtg gctgaccatc gtttgcagac gttcttgtgc
     3901 ttcatgttgc agatgctctt caaaacgacg cacatcagcg gcaaaacggt gcaggctcag
     3961 gctggctgac ccgggtagta cgtgaagtag atgaataact ccgtcatcct gggcgaggaa
     4021 ttcagcgtgg cgaacagctt tgtcgctcaa ttccatttca aatacatcaa ctggcataat
     4081 gattgtctta tacataaccc tttctccctg ttaatcatga acaaatcatt cgccatgatt
     4141 ataatattta tccctgatat ttgtctggtt ctttttcctt acgaactgtt tctgtgatga
     4201 atatattctc actgaacacc aggaattctc ccaaaacctg tggtaccgcc cgttttcccg
     4261 ctgtgatagc tacccttaaa gactgactct tttttgaact gtctctggag gttgcatgaa
     4321 agcattgact tatcacggcc cacatcacgt tcaggtagaa aatgttcccg atccgggcgt
     4381 tgaacaggca gatgatatta ttctgcgtat tacggcaacg gcgatctgtg gctctgacct
     4441 ccatctttat cgaggcaaaa tacctcaggt taaacatggc gatatttttg gtcatgaatt
     4501 tatgggggaa gtagttgaaa ccggaaagga cgtaaaaaat ttgcaaaaag gcgaccgagt
     4561 ggtaattccg ttcgtcattg cttgtggcga ctgttttttc tgtcgattgc aacaatatgc
     4621 cgcctgcgaa aataccaatg cgggtaaagg cgctgcgctc aataaaaaac agataccagc
     4681 tccagcggca ttgtttggtt atagtcacct gtatggcggc gttcctggtg ggcaggcgga
     4741 atatgtccgc gtccctaaag ggaatgtggg gccgtttaaa gtaccgcctt tgctttcaga
     4801 tgataaagcg cttttccttt ctgatattct gccaacggca tggcaggcag caaaaaatgc
     4861 gcagatccaa caaggttcaa gcgttgcagt ctatggtgct ggtcctgtgg gattgttgac
     4921 aatcgcctgt gcacggttgc tcggtgcgga acagattttt gttgttgatc atcatcccta
     4981 ccgcttgcat ttcgccgccg accgctacgg cgcgatcccg attaattttg atgaagacag
     5041 cgatccggca cagtcaatta ttgaacaaac ggcaggtcac cggggcgtgg atgcagtaat
     5101 agacgccgtc ggttttgaag cgaaaggcag caccacggaa acggtgctga ctaacctgaa
     5161 actggagggc agcagcggta aagcgttgcg tcagtgtatt gcggcggtca ggcgtggcgg
     5221 cattgttagc gtaccgggcg tctacgctgg atttattcac ggtttcctgt ttggcgacgc
     5281 ctttgataaa gggttgtcgt ttaaaatggg acagacccac gttcacgcat ggctgggaga
     5341 attattaccg ttaattgaga aaggattact gaaaccagaa gaaattgtta cccactatat
     5401 gccgtttgaa gaggccgccc ggggatatga gattttcgaa aaacgtgaag aggagtgccg
     5461 taaggtgatt ctggtacccg gtgcacaaag cgcagaggcg gcgcagaagg cggtttcagg
     5521 tctggtgaat gcgatgccgg ggggaacaat atgatcgtca ggagtggttt tcgaggtaaa
     5581 ggacagccat gacgataatc gccgccataa tcagaaatcc tatcaggatg taaaatgctt
     5641 ctgccatggt tattcccaca aacgaaacgg aataattttg cagcaaaagt gaacagtgag
     5701 aaccaggaaa aattgctgat tttgcgtaaa gaggatgcga gtgcatcctc tgggcaaagc
     5761 gagttatcgc ttgtgcagat gggattaaag caggtagtcg ccagcagctt ctggctggta
     5821 ttcgagttcc agcacttcaa ggtgggttgc aacgccgccc ggaagttccc agtgaatgga
     5881 atcgccaacg cgcagcccca gcagtgcggc acctaccgga gccataacgg aaagctgagt
     5941 attgctatcg gtcatttttg ccggatacac cagcgtgcgc acacgcactt cgccatcgct
     6001 aagattgcgg aatttaaccc ggctgttcat tgtcaccacg tcgtgtggca tctcttctgg
     6061 cgaacacatt tgggcgcgat ccaactctgc gtttaacgcg tcggcgattg gcaaaccagc
     6121 ataggcgggt tgctccagca gaatatcgat gcgttcggca tccaggtcgt taatgatgat
     6181 agttggtctg gacattttta ctccatgtcg tcggtgctgc gagtgtcgca gataaacata
     6241 cccaaaagaa aaccctcacc gtcaggcggc gagggtttaa ctcacatgat gatactgact
     6301 gttgctcact ctttgaagtg atttgcgtca cattcaggga attcctcaat gcagcgcatt
     6361 atgtataaat cttaatcgcc ttggtttatg gaagacgaat tagcgtgttt tgtaaatcag
     6421 atgattaata acccgcttta tcaatcacaa aggttttgcc acagttacct gggtgaggtt
     6481 gtggcaagaa tgagtttgca gaaagcggag cgttgatggc gtcagctttg atcgagatct
     6541 gaatttcagt caaatacgca gggttaccct ggcacgttag cttaactgct ttcacgttct
     6601 cttttcccca gcttttggca aaggcggcgt caaagtcacg gcggctcact gttttaccgt
     6661 aattatccgc aaggaatttt ccggcttcgc tctctttaat ttcttgattc aggcgtacca
     6721 tcgtaccgaa gtatgcgtcc ggatcaaaac caaagcaggc accgtgtttg gcatattcgt
     6781 agcgttccag gcaggaacgt ccgccagctc ctggcatgac ttcacttagt ttagcggccg
     6841 tttccagtga taatccggtt tccggcgatg aacacattcg gctggcgcgc gcttctggta
     6901 gattcgggat tgggcgagta gcgcaaccga agcgcatcca gcggcgttca tcaacaccac
     6961 gggcagcaac cgatttaggc aatcctggcc acagaccatg tacggtcaga aaatcagctt
     7021 tgttggtcgt ttcggtttgc aggcgacatt catctcgttc gttacgattt cgatcgtgtt
     7081 gactctggca aaatccggtt tgccaggaga gggccaggac atagcgatca aaatcgccat
     7141 actgttttgc ctgcaacgct aaggcgttgg cagaagagaa gggaagcaga gaaaccgcga
     7201 gcaacgcggc gttacgccag aatgctttca taatgggtgt ggaactcata catacactga
     7261 atactatcta ttaaatcata aaaaagcccg ccaggtgggc ttacctggcg ggcgtgatga
     7321 tttattcagc gtttggcgaa cgtattagtt ccacatggcg agaatcggcc agccaaccaa
     7381 cagcaacata gagatgtaaa tcaccccgaa gattgcgcca agacgccagt aatcttttga
     7441 tttcacatag ccacagccgt aaataatcac cccaggaccg gttgcatacg gcgtcagaca
     7501 gcccatgata ccgatagaca gcaccagcag gatacacagt tgttccattg gtacgcccgg
     7561 aataccttta ccgacggcca gaataaccgg cagcatggtt gcggtgtgcg cagacaggct
     7621 ggcaaacagg tagtgtgcaa agtagaacac cagaaccagt acaatcaccg ttgcgtttgg
     7681 tgagaatcct tccaggtgcg tactcatggt accggcgaac cagtcaataa aaccagaacg
     7741 agtcaggccg ttagccatca caaccagagt tgccaggttg accagtgtgt tccatgcgct
     7801 gttatagcgg gtaatgtctt tccaaggcac aacgtgcagg gccagcatta gcgaaactgc
     7861 cagcagacca accgcagtag cattaatgac ttcactgcca aatacccaca aacctaagct
     7921 gagcaataca aggccaatca gtgtccactc tctgcgtgtc agcgcaccca tggttttcag
     7981 ttcatcaccc gcccaggttg ccacttcttc actgtgtgtg atttccggtt tgtacagcac
     8041 gtaggaaagc cacggcgcaa tgataagcaa gataacccca accggcagga agcagaggaa
     8101 ccactgcaac cagctaatct ggataccggc aattttgctg acgaactcca gacccagcac
     8161 gtttggtgcc gctccggtga caaacatgga cgaactcaga ctggtactaa tgaccatcat
     8221 ccacatcaaa tagccgccaa tacgacgcgc ggacggatcg ttcgggaatg atttaaacaa
     8281 cggcggcagg tttttaatga ccggaaaaac cgtacccccg gtacgcgcgg tgttggaagg
     8341 tgtaaacggt gccagcagaa tgtcgataat gacaatcgca taacccaacg tcagcgtgcg
     8401 tttgcccatg aatttcacca ggaaaagggc aatgcgacga cctaacccgg aaacttcata
     8461 ccctaatgca aaaataaatg cgccaaatac cagccatacc gtggtgctgg aaaaaccagc
     8521 caggccccat ttcagcgcct gtttttgcgc attaaacgct gggtcagcta attctttggc
     8581 atcaaagagc aggtaattac tgccaataac gcaaatagta accgcaataa aactgatcgc
     8641 tgttgccgga attggctcga ggatcatgcc gacaatcatt gccacaaaca cagcgaagta
     8701 atgccatgcc tgcggcggca taccgtcggg gacagggata agaaacatga cacccatcac
     8761 caccagtggg gccaatagtt tccatatatt
//
LOCUS       DAPHKZ010000162         8688 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.163, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000162 DAPHKZ010000000
VERSION     DAPHKZ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8688
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.163"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(105..725)
                     /gene="entD"
                     /locus_tag="RH288_004116"
     CDS             complement(105..725)
                     /gene="entD"
                     /locus_tag="RH288_004116"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HDV4033111.1"
                     /translation="MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGR
                     KRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGTTALAVVSRQ
                     PIGIDIEEIFSVQTARELTDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKASEI
                     QTDAGFLDYQIISWNKQQVIIHRENEMFAVHWQIKEKIVITLCQHD"
     gene            complement(900..3140)
                     /gene="fepA"
                     /locus_tag="RH288_004117"
     CDS             complement(900..3140)
                     /gene="fepA"
                     /locus_tag="RH288_004117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore enterobactin receptor FepA"
                     /protein_id="HDV4033112.1"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG
                     QNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM
                     SVNTHF"
     gene            3383..4585
                     /gene="fes"
                     /locus_tag="RH288_004118"
     CDS             3383..4585
                     /gene="fes"
                     /locus_tag="RH288_004118"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HDV4033113.1"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYS
                     TIKRVWVYITGVTDHHQNSQPQSMQRIAGTNVWQWTTQLNANWRGSYCFIPTERDDIF
                     SVPSPDRLELREGWRKLLPQAIADPLNLQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PEIPAKEIIWKSERLKKSRRVWIFTTGDATAEERPLAVLLDGEFWAQSMPVWPVLTSL
                     THRQQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPLVKAIAPFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGVLLEKLKAGEVSAEG
                     LRIVLEAGIREPMIMRANQALYAQLHPIKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     gene            4588..4806
                     /gene="ybdZ"
                     /locus_tag="RH288_004119"
     CDS             4588..4806
                     /gene="ybdZ"
                     /locus_tag="RH288_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis protein YbdZ"
                     /protein_id="HDV4033114.1"
                     /translation="MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCVLPAGWDIVCQPQ
                     SQASCQQWLEAHWRTLTPTNFTQLQEAQ"
     gene            4803..8684
                     /gene="entF"
                     /locus_tag="RH288_004120"
     CDS             4803..8684
                     /gene="entF"
                     /locus_tag="RH288_004120"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HDV4033115.1"
                     /translation="MSQHLPLVAAQPGIWMAEKLSELPSAWSVAHYVELTGEVDSPLL
                     ARAVVAGLAQADTLRMRFTEDNGEVWQWVDDALTFELPEIIDLRTNIDPHGTAQALMQ
                     ADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCTW
                     LRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLPGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFM
                     RRLGSAALTATGPVLNVLPLGIHIAAQETLPELATRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGDEPLFGPVLNIKVFDYQLDIPDVQAQTHTLATGPVNDLELALFPDVHGDLSI
                     EILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQLNATQV
                     EIPETTLSALVAEQAAKTPDAPALADARYLFSYREMREQVVALANLLRERGVKPGDSV
                     AVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF
                     SDVPNLTSLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFF
                     AEYGVTTTHFVPSMLAAFVASLTPQTARQSCATLKQVFCSGEALPADLCREWQQLTGA
                     PLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSG
                     LPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKAQAPGRAP
                     KAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQVARQVTPGQVM
                     VASTVAKLATIIDAEEDSTRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYL
                     DPQWSIIGIQSPRPNGPMQTAANLDEVCEAHLATLLEQQPHGPYYLLGYSLGGTLAQG
                     IAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGS
                     TSTELFTTIEGNYADAVRLLTTAHSVPFDGKATLFVAERTLQEGMSPERAWSPWIAEL
                     DIYRQDCAHVDIISPGTFEKIGPIIRATLNR"
BASE COUNT         1884 a         2345 c         2384 g         2075 t
ORIGIN      
        1 atccccgcat atccggttgt caggtcagga tggtaaggca cctgctttac actttcgccc
       61 gtggtcagtg atggctgcgg gcgaatcgta ccagatgttg tcaattaatc gtgttggcac
      121 agcgttatga ctatcttttc ttttatctgc cagtgcacag caaacatctc attctcacga
      181 tgaatgatga cctgctgttt attccagcta attatctgat agtccagaaa acctgcatca
      241 gtttggatct cacttgcctt aaatgcgctc tctttggcgg aaaatgccag tgtcagcgcc
      301 agagaaaagg ctaaaccgca gtctgcgagt cgctcgtgtt ccgctggtgt aataatgttg
      361 tctgtcaatt ctcttgcggt ttgtacagaa aaaatttctt ctatatcaat gccaatcggt
      421 tgacgagata ccacggctaa tgccgtagtc ccacagtggc taatactgcc gtatacctcc
      481 gcaggccaga caggttggcg tagctcgccg attgcgggca cacatttata gccatattcc
      541 cgcaaagcat aaacagcagc gatccgtccg gctaaatgct ctgttttacg tttacgtcca
      601 gcgtgttgca gttgtgcgta gtgcggcagc cagagtaaat cctgctcaca aaaattcgcc
      661 ggatcgaact caacaaaatg cagcgtatgt ccggcaaagg ggagggaggt atgcgtagtt
      721 ttcatatcga ccatattcga gactgatgac aaacgcaaaa ctgcctgatg cgctacgctt
      781 atcaggccta catggtcctg caatatattg aattggcaag atttttgtag gccggataag
      841 gcgttcacgc cgcatccggc atgaacgacg cgcactttgt caacaatctg acgttagcat
      901 cagaagtggg tgtttacgct catataccac gtacgtcccg gctcgttata ggtatacgcc
      961 ccggcaccgg cgatatagtt ggcccctgcc aaatcgcccg tggtctgggc attacccgca
     1021 cgccacaaac gtttgtcgaa cagattgtcc acgccgccgg tcagactgac attcttcgtc
     1081 acatcccagg tcgcgctcag gccaacaatg ctgtaaggac taatttcttt ggtttccggt
     1141 ccaaccgctg gctgaccttt atagttgtac ttcttcggct gctgcttgcc gtaccaggtg
     1201 aaggtcgttt gcatcgacaa atcttcccgt gcctgccagc tcagcgttga gttcaacgta
     1261 tactccggga tgatcgacaa acggtcgccc gtggttttgt tttcactctt cagcatataa
     1321 gtgatgttat tggtccacat caccgtttcg ctaaccggta cgtttaacga tccttccaga
     1381 ccttcaacca ccgctttcgg cacgttatcc cactgataga gatcggtgcc gactgcgttt
     1441 tgccctacag ccacatagcc cgcttcaatc ttattgcgat aatcgttacg gaaccaggtg
     1501 acgcccgcca gccacccgtc gcgtttgaac tccagaccaa tctctttgtt gatgctggtt
     1561 tctgctttca ggtcatcgtt accttgcaga tagcagccgc ccgcgctggc atagcaaccc
     1621 tgacctttac tgtagagaat gtagttcggg ttagtctggt acaggctcgg cgctttataa
     1681 gcacgggcga tgcccatttt cagcgtgaag tcatcgccta aaccttgcga tatgttcagc
     1741 gccgggctcc agttattgcc gacaatactg tgatgatcga aacgcagccc cggcgttacg
     1801 atggtgctgt cagtcagctc catgttgttt tcggcaaaca gcgagaaaat ttctgctttt
     1861 gaatacgggc tacggtcggt ggtactcacg ccatcaatag cgccaccggt attcgttccg
     1921 gtcagtgcct gggtgttgga acttaagtcc ttcatccgtt gctgattcca ctccgtaccc
     1981 agcgtcagcg tctggttaac gaggaaatca atcggcaggt taacttcgct gtgcagcatc
     2041 acgtcatcaa gatcgatatc gacgaaatcc tgtgtcgctt tttcgttaaa tttcccttcg
     2101 gtaccgcccg ccagaccttc cggaatacgc gagttacggg tgtgttcgta ctgcacccag
     2161 ttgctggtgg tcacgccgtt atcccagcca ccgttccagg tcagcgcgta gttctggcga
     2221 tacagacggt tggtttcatc gccatatttc gagcgggtat aggaatcgga gttggtattc
     2281 tgggtgtcgc ccgcatacag gttaccctgg cggctgtaac ctgcttccag ttccagcgat
     2341 tgcaatggcg cgaaatccca gcgcaccacg ccattaatat ctttgttgat taccccttcg
     2401 cgcccggctg gtaacgtcgt ggcatacgtt ccggcacgcg cggactgatg gccctggttg
     2461 atatcccacg cgtcagcctg ggttttgtcg aggttgccat acaaacggaa gctgaattcg
     2521 tcgcccagcg gaccggtcag gctaaagtta gtgcgtttgg tggcaccttc ctctttatgt
     2581 tctggcgcat tgaaatatgc gtcccaggag ccgtgccact cgccgctgcc ttttttggta
     2641 atgatgttaa ccacgccgcc cgccgcgccg ttgccataac gcgcagctgc cggaccacgc
     2701 agaacttcaa tacgttcaat catttcaggt ggcacccagg aagtatcacc acgggtatcg
     2761 cgctcgccac gccagccctg acgcaccgag ttacggctgc ttaccggctt gccgtcaatc
     2821 aaaatcagcg tgttttccgg acccataccg cgaatatcaa tctgtcggtt attcccacgc
     2881 tgaccactgg tggagttacc ggtcaggtta acgcctggca tggtacggat gatctccgac
     2941 acatcgcggg caaccgggtt tttgcggatt tcatctgcgg tgatggtcga aacgccaggc
     3001 gcctgtaagt tctgctcggc ggcggtaacg acaatagtat cgtcatgtga aacaggagta
     3061 tcggtcggct cttgtgcctg cgctacccca taaatcccca gattgaccaa caaggccagg
     3121 gaatgaatct tcttgttcat tgttttattc ctgcattttt gccacgaatt gcaactgtcg
     3181 ggcatggtcg tcatcaacac gacgcatccc gctaccgcga aaacctttga tcctgaaaga
     3241 cacgcagtgc agttggttaa ttaatgtccg cgcttcccac ggcgcgccat tacgctattg
     3301 caaatgcaaa tagttatcaa taatattatc aatatatttc tgcaatcaat gaaaaattgc
     3361 acagtaaaca tggggttatg gtgtgacggc gttaaaagta ggaagtgaga gctggtggca
     3421 gtcgaaacat ggcccggaat ggcagcgtct gaatgacgaa atgtttgagg tcactttctg
     3481 gtggcgtgat ccccaaggtt ctgaagaata ctcgacgata aagcgcgtat gggtctacat
     3541 cactggtgtg accgatcacc atcagaacag ccagccccag tcgatgcagc gaattgcagg
     3601 cactaacgtc tggcagtgga cgacacaact caatgccaac tggcgcggca gctactgctt
     3661 tattcccacc gaacgcgatg acattttttc tgtaccatcc cccgatcgcc tcgaattgcg
     3721 cgaaggctgg cgaaaactat taccccaggc gatagccgat ccgctgaacc tacaaagctg
     3781 gaaaggcggg cgagggcacg ctgtttctgc actcgaaatg ccgcaagcgc ctctgcaacc
     3841 gggatgggat tgtccgcaag cgccagaaat acctgccaaa gaaattatct ggaaaagtga
     3901 acggttgaaa aagtcacggc gtgtatggat ttttaccacc ggcgatgcaa cagcagaaga
     3961 acgcccgctg gcagttttgc tcgatggcga attttgggcg caaagtatgc ccgtctggcc
     4021 agtgctgact tcgctgaccc atcgtcagca acttcctccc gccgtgtatg tgttgatcga
     4081 cgctatcgac accacgcacc gcgcccacga actgccgtgt aatgcggatt tctggctcgc
     4141 agtacagcaa gagttattac ccctggtgaa agctattgcc ccttttagcg atcgtgccga
     4201 tcgcaccgtg gttgccgggc agagttttgg tgggctttcc gcgctgtatg ccggactgca
     4261 ctggcctgaa cgctttggct gtgtattaag ccagtcagga tcgtactggt ggccgcatcg
     4321 gggcgggcag caagagggcg tgttacttga aaagctaaaa gctggtgaag ttagcgccga
     4381 aggtctgcgc attgtgctgg aagcgggtat tcgcgagccg atgatcatgc gggccaatca
     4441 ggcgctgtat gcgcaattac accccataaa agaatccatt ttctggcgtc aggttgacgg
     4501 cggacatgat gcgctttgtt ggcgcggtgg cttgatgcag gggctaatcg acctctggca
     4561 accacttttc catgacagga gttgaatatg gcattcagta atcccttcga tgatccgcag
     4621 ggagcgtttt acatattgcg caatgcgcag gggcaattca gtctgtggcc gcaacaatgc
     4681 gtcttaccgg caggctggga cattgtgtgt cagccgcagt cacaggcgtc ctgccagcag
     4741 tggctggaag cccactggcg tactctgaca ccgacgaatt ttacccagtt gcaggaggca
     4801 caatgagcca gcatttacct ttggtcgccg cacagcccgg catctggatg gcagaaaaac
     4861 tgtcagaatt accctccgcc tggagcgtgg cgcattacgt tgagttaacc ggagaggttg
     4921 attcgccatt actggcccgc gcggtggttg ccggactagc gcaagcagat acgctgcgga
     4981 tgcgttttac ggaagataac ggcgaagtct ggcagtgggt cgatgatgcg ctgacgttcg
     5041 aactgccaga aattatcgac ctacgaacca acattgatcc gcacggtact gcgcaggcat
     5101 taatgcaggc ggatttgcaa caagatctgc gcgtcgatag cggtaaacca ctggtctttc
     5161 atcagctgat acaggtggcg gataaccgct ggtactggta tcagcgttat caccatttgc
     5221 tggtcgatgg ctttagtttc ccggccatta cccgccagat cgccaatatt tactgcacat
     5281 ggctgcgtgg cgaaccaacg cctgcttcgc catttacgcc tttcgctgat gtagtggaag
     5341 agtaccagca ataccgcgaa agcgaagcct ggcagcgtga tgcggcattc tgggcagaac
     5401 agcgtcgtca actgccgccg cccgcgtcac tttctccggc acctttaccg gggcgcagcg
     5461 cctcggcaga tattctgcgc ctgaaactgg aatttaccga cggggaattc cgccagctgg
     5521 ctacgcaact ttcaggtgtg cagcgtaccg atttagccct tgcgctggca gccttgtggc
     5581 tggggcgatt gtgcaatcgt atggactacg ccgccggatt tatctttatg cgtcgactgg
     5641 gctcggcggc gctgacggct accggacccg tgctcaacgt tttgccgttg ggtattcaca
     5701 ttgcggcgca agaaacgctg ccggaactgg caacccgact ggcagcacaa ctgaaaaaaa
     5761 tgcgtcgtca tcaacgttac gatgccgaac aaattgtccg tgacagcggg cgagcggcag
     5821 gtgatgaacc gctgtttggt ccggtactca atatcaaggt atttgattac caactggata
     5881 ttcctgatgt tcaggcgcaa acccataccc tggcaaccgg tccggttaat gaccttgaac
     5941 tggccctgtt cccggatgta cacggtgatt tgagtattga gatcctcgcc aataaacagc
     6001 gttacgatga gccaacgtta atccagcatg ctgaacgcct gaaaatgctg attgcccagt
     6061 tcgccgcgga tccggcgctg ttgtgcggcg atgtcgatat tatgctgcca ggtgagtatg
     6121 cgcagctggc gcagctcaac gccactcagg ttgagattcc agaaaccacg cttagcgcgc
     6181 tggtggcaga acaagcggca aaaacaccgg atgctccggc gctggcagat gcgcgttacc
     6241 tgttcagcta tcgggaaatg cgcgagcagg tggtggcgct ggcgaatctg ctgcgtgagc
     6301 gcggcgttaa accaggggac agcgtggcgg tggcactacc gcgctcggtc tttttgaccc
     6361 tggcactcca tgcgatagtt gaagctggag cggcctggct accgctggat accggctatc
     6421 cggacgatcg cctgaaaatg atgctggaag atgcgcgtcc gtcgctgtta attaccaccg
     6481 acgatcaact gccgcgcttt agcgatgttc ccaatttaac aagcctttgc tataacgccc
     6541 cgcttacacc gcagggcagt gcgccgctgc aactttcaca accgcatcac acggcttata
     6601 tcatctttac ctctggctcc accggcaggc cgaaaggggt aatggtcggg cagacggcta
     6661 tcgtcaaccg cctgctttgg atgcaaaatc attatccgct tacaggcgaa gatgtcgttg
     6721 cccaaaaaac gccgtgcagt tttgatgtct cggtgtggga gtttttctgg ccgtttatcg
     6781 caggggcaaa actggtgatg gctgaaccgg aagcgcaccg cgacccgctc gctatgcagc
     6841 aattctttgc cgaatatggc gtaacgacca cgcactttgt gccgtcgatg ctggcggcat
     6901 ttgttgcctc gctgacgccg caaaccgctc gccagagttg cgcgacgttg aaacaggttt
     6961 tctgtagtgg tgaggcctta ccggctgatt tatgccgcga atggcaacag ttaactggcg
     7021 cgccgttgca taatctatat ggcccgacgg aagcggcggt agatgtcagc tggtatccgg
     7081 cttttggcga ggaactggca caggtgcgcg gcagcagtgt gccgattggt tatccggtat
     7141 ggaatacggg tctgcgtatt cttgatgcga tgatgcatcc ggtgccgccg ggtgtggcgg
     7201 gtgatctcta tctcactggc attcaactgg cgcagggcta tctcggacgc cccgatctga
     7261 ccgccagccg ctttattgcc gatccttttg ccccaggtga acggatgtac cgtaccggag
     7321 acgttgcccg ctggctggat aacggcgcgg tggagtacct cgggcgcagt gatgatcagc
     7381 taaaaattcg cgggcagcgt atcgaactgg gcgaaatcga tcgcgtgatg caggcgctgc
     7441 cggatgtcga acaagccgtt acccacgcct gtgtgattaa ccaggcggct gccaccggtg
     7501 gtgatgcgcg tcaattggtg ggctatctgg tgtcgcaatc gggcctgccg ttggatacca
     7561 gcgcattgca ggcgcagctt cgtgaaacat tgccaccaca tatggtaccg gtggttctgc
     7621 tgcaacttcc acagttacca cttagcgcca acggcaagct ggatcgcaaa gccttaccgt
     7681 tgcctgaact gaaggcacaa gcgccagggc gtgcgccgaa agcgggcagt gaaacgatta
     7741 tcgccgcggc attctcgtcg ttgctggggt gtgacgtgca ggatgccgat gctgatttct
     7801 tcgcgcttgg cggtcattcg ctactggcaa tgaaactggc agcgcagtta agtcggcagg
     7861 ttgcccgcca ggtgacgccg gggcaagtga tggtcgcgtc aactgtcgcc aaactggcaa
     7921 cgattattga tgctgaagaa gacagcaccc ggcgtatggg attcgaaacc attctgccgt
     7981 tgcgtgaagg taatggcccg acgctgtttt gtttccatcc tgcgtccggt tttgcctggc
     8041 agttcagcgt gctctcgcgt tatctcgatc cacaatggtc gattatcggc attcagtcac
     8101 cgcgccccaa tggccccatg cagacggcgg caaacctgga tgaagtctgc gaagcgcatc
     8161 tggcaacgtt acttgaacaa caaccgcatg gcccttatta cctgctgggg tattcccttg
     8221 gcggtacgct ggcgcagggt attgcggcgc gactgcgtgc ccgtggcgaa caggtggcat
     8281 ttcttggctt gctggatacc tggccgccag aaacgcaaaa ctggcaggaa aaagaagcta
     8341 atggtctgga cccggaagtg ctggcggaga ttaaccgcga acgcgaggcc ttcctggcag
     8401 cacagcaggg aagtacttca acggagttgt ttaccaccat tgaaggcaac tacgctgatg
     8461 ctgtgcgcct gctgacgact gctcatagcg taccgtttga cggtaaagcg acgctgtttg
     8521 ttgctgaacg cacacttcag gaaggtatga gtcccgaacg cgcctggtcg ccgtggatag
     8581 cggagctgga tatctatcgt caggattgtg cgcatgtgga tattatctct ccagggacgt
     8641 ttgaaaaaat tgggccgatt attcgcgcaa cgctaaacag gtaaatta
//
LOCUS       DAPHKZ010000163         8634 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.164, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000163 DAPHKZ010000000
VERSION     DAPHKZ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8634
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.164"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(169..1833)
                     /gene="glnS"
                     /locus_tag="RH288_004121"
     CDS             complement(169..1833)
                     /gene="glnS"
                     /locus_tag="RH288_004121"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HDV4033116.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSD
                     YFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEK
                     MRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRAD
                     FREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADG
                     RKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSL
                     KDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE"
     gene            complement(2101..4047)
                     /gene="nagE"
                     /locus_tag="RH288_004122"
     CDS             complement(2101..4047)
                     /gene="nagE"
                     /locus_tag="RH288_004122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HDV4033117.1"
                     /translation="MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVAFIAQA
                     GGAIFDNLALIFAIGVASSWSKDSAGAAALAGAVGYFVLTKAMVTINPEINMGVLAGI
                     ITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHAIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGV
                     TEPLEFLFMFLAPLLYLLHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAS
                     QNVWMLLVMGVVFFAIYFVVFSLVIRMFNLKTPGREDKEDEIVTEEANSNTEEGLNQL
                     ATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDTMCKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDAMKKVVARGPVAAASAEATPATAAPVAKPQAVPNAVSIAELVSPITGD
                     VVALDQVPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEI
                     VVHMGIDTVALEGKGFKRLVEEGAQVSAGQPILEMDLDYLNANARSMISPVVCSNIDD
                     FSGLIIKAQGHVVAGQTPLYEIKK"
     gene            4380..5180
                     /gene="nagB"
                     /locus_tag="RH288_004123"
     CDS             4380..5180
                     /gene="nagB"
                     /locus_tag="RH288_004123"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDV4033118.1"
                     /translation="MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGT
                     PMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEG
                     CVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL"
     gene            5240..6388
                     /gene="nagA"
                     /locus_tag="RH288_004124"
     CDS             5240..6388
                     /gene="nagA"
                     /locus_tag="RH288_004124"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDV4033119.1"
                     /translation="MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQNANEKSGCTNYLPTLITT
                     SDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLC
                     KNADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLY
                     NAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRM
                     ATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITRTIVNGNEVVTQ"
     gene            6397..7617
                     /gene="nagC"
                     /locus_tag="RH288_004125"
                     /gene_synonym="nagR"
     CDS             6397..7617
                     /gene="nagC"
                     /locus_tag="RH288_004125"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HDV4033120.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITL
                     FDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
                     DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFN
                     PQKIVIAGEITEADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKR
                     AMLNGILLQHLLEN"
     gene            7665..8417
                     /gene="nagD"
                     /locus_tag="RH288_004126"
     CDS             7665..8417
                     /gene="nagD"
                     /locus_tag="RH288_004126"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HDV4033121.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNY
                     PSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSSLDDIDSMPFRPSWIYPSVAEIDVI"
BASE COUNT         2122 a         2276 c         2179 g         2057 t
ORIGIN      
        1 ggcgtgaacg ccttatccgg cctacaaaag cacgcaaact caatatattg cagagatcat
       61 gtaggcctga taagcgtagc gcatcaggca atttagcgtt tgaaactgtt tgtctgttcc
      121 ttgccggatg cgacgtaaac gccccatccg gcatagcgaa acttaaaatt actcgcctac
      181 tttcgcccag gtatcacgca gcccaacggt gcggttaaat accggttttt ccgccgtaga
      241 atggcggcta tcgaggcaga agtaaccttc acgctcaaac tggaatgctt tacccgcaac
      301 cgcatctttc agcgacggtt cagcaaagcc ctgtttgatc accagcgatt ccgggttaat
      361 caccgacagg aaatcatccg cagcacctgg gttaggcacg ctgaacagac ggtcatacaa
      421 acggatttca accggcagcg catgtgccgc gctcacccag tgaataacac ctttgacttt
      481 acgaccatct gccggatctt tgcttaaggt atcggcgtca taagtacaga agatggtggt
      541 gatattacct tcggcatctt tctcgacgcg ttctgcctta atcacataag cattacgcag
      601 acgcacttct ttacccagca ccagacgttt gtactgcttg ttagcttctt cgcggaaatc
      661 ggcgcgatca atccaaatct caccgctaaa cggcacctga cggctgccca tttccggttt
      721 gttcggatgg ttcggcatgg taaccatttc gccttcgccc tgatagtttt cgataaccag
      781 tttcaccgga tcgataaccg ccattgcgcg cggcgcattt tcgttgagat cttcacggat
      841 gcaggattcc agcgacgcca tctcaatggt gttgtcctgc ttggtcacgc cgatgcgttt
      901 gcagaactca cgaatagaag ccgcagtgta accacgacga cgcagaccgg aaatggtcgg
      961 catacgcggg tcatcccagc cttcaacgtg cttgtcggtc accagcaggt tcaacttacg
     1021 cttggacatc acggtgtatt ccagattcag gcgcgagaac tcatactggc gcgggtgaac
     1081 aggaatcgtg atgttgtcca gtacccagtc gtacagacga cggttgtcct ggaactcaag
     1141 cgtacacaga gagtgcgtaa taccttccag ggcatcgctg atgcagtggg tgaagtcgta
     1201 catcgggtag atgcaccact tgttgccagt ctggtggtgt tcagcaaatt taatacggta
     1261 cagcaccgga tcgcgcatca cgataaacgg tgaagccatg tcgattttcg cacgcaggca
     1321 ggctttacct tcttcaaaac caccggcacg cattttttcg aacagcgcca ggttctcttc
     1381 aacgctgcgg tcgcggtacg ggctgttttt acccggttgc gtcagggtgc cgcggtattc
     1441 gcggatctgt tccggcgtca gttcatcaac gtacgccagg cctttattga tcagttcgat
     1501 cgcataggcg tggagctgat caaaataatc ggaggagtaa cggacgttac cagaccagtg
     1561 aaaacctaac cactctacgt cgtttttgat cgactcaaca tactcgatat cttcttttac
     1621 cgggttagtg tcgtcgaaac gcaggttgca ctggccttta tagtcctggg cgatcccgaa
     1681 gttcaggcag atagatttcg catggccaat atgcagatag ccattcggct ccggcgggaa
     1741 acgggtgtgt actgtggtgt gcttaccact ggccagatct tcatcgatga tctgacggat
     1801 aaagttagtc gggcgggctt ctgcctcact catcgtggat tcctcaaagc gtaaacaacg
     1861 tataacggcg tatgatctta taagcgggac aggctgacaa ctgttagtta gtgaaaatcg
     1921 aaaatctcac tgagattatg gggatgattg atgaaaaaaa aagcggcaga gaagatctcc
     1981 accgcttttg ccagtcctgc gtcattgttg gatgcgacgc ttaagcgtct tatccaacct
     2041 ggactgagct tttgtaggcc tgataagacg cgtcaagcgt cgcatcaggc ataaagcaga
     2101 ttactttttg atttcataca gcggtgtttg acccgccaca acatggccct gagctttaat
     2161 gatcaagcca ctgaaatcgt cgatattgct gcaaaccacc gggctaatca tcgagcgggc
     2221 gttagcgttc aggtaatcca gatccatttc cagaatcggt tgccctgcgc ttacctgcgc
     2281 accctcttcc accagacgtt taaagccttt accttccagc gctacggtgt cgatacccat
     2341 atggacgacg atctccgcgc ctttttcggt ttccaggcag aacgcgtggt tggtgttgaa
     2401 gattttcacg attgtccctg cggctggtga tacgacgatt ttatctgtcg gtttcaccgc
     2461 cacaccgtca cccaccgctt tgctggcgaa tgcttcgtca ggaacctgat ccagtgccac
     2521 gacatcaccg gtaatcggcg ataccagctc cgcgatagat accgcgtttg gtacagcctg
     2581 cggttttgct acaggcgcgg cagttgccgg agttgcttca gctgacgcag ctgctaccgg
     2641 accgcgggca acgactttct tcatcgcatc gccgatggat tctgctttcg cgccaacaat
     2701 cacctgaata gtctgtttgt tcagttttac tacaccagaa gcacccagac gtttacacat
     2761 cgtatcgtta acgcgggcag agtcagccac tgtaaggcgc agacgggtga tacaggcgtc
     2821 aattgctttc aggttgtcag tgccgccaac cgcagcaata tagttggtcg ccagttgatt
     2881 gaggccttct tcagtgttgc tgttggcttc ttcagtaacg atctcgtctt ctttatcttc
     2941 acgacccggc gttttcaggt tgaacatgcg gataaccaaa ctgaacacca cgaagtagat
     3001 agcgaagaag acaacaccca tcaccagcag catccagacg ttctggctgg cggccggcag
     3061 gttatacatc aacgcgtagt cgatagcccc cgcagagaaa gagaagccag catggatacc
     3121 cagcagtgtt gccacaaaca ggctgatacc ggtcagcagt gcgtgcagga ggtacagcag
     3181 cggtgcaagg aacatgaaca ggaattccag cggctcagtc acaccggtca ggaacgcagt
     3241 aacagcaaca gaaagcagca tcccgccaac catcggacga cgctctttcg gtgctgcgaa
     3301 gtacatcgcc agcgccgcac ccggcagacc gaacatcata atcgggaaga agccggacat
     3361 gaacatcccc gcggtgccgt caccggcata gaagcggttg atatcaccgt ggaaaaccgt
     3421 acccgccgcg ttggtgaatt caccaatctg gaaccaggcg atggtgttca gcacctgatg
     3481 cagaccggtt gggatcagca gacggttgat gaaaccaaag ataccggaac ccagcgcgcc
     3541 cgcagaaacg atccactcgc ctcctgcatg gatagcgtgc tgtaccggcg gccagacgta
     3601 accaaaaatg gccgccagca ccaggcagaa gaagccggtg gcaatcggca caaagcgttt
     3661 gccgccgaag aagctcagga agtccggcag tttaatatcg gaccaacggt tataggctgc
     3721 gccaccaacc agaccggtaa tgatacccgc cagtacaccc atgtttattt ctgggttgat
     3781 ggtcaccatc gctttggtta acacaaagta acctaccgca cccgccagcg ccgccgcacc
     3841 tgcgctgtct ttcgaccagc tggatgccac accgatggcg aagattaatg cgaggttatc
     3901 aaaaatcgca ccgcccgcct gggcaataaa cgcaacgtta agtaaatctg gctgaccgaa
     3961 tcgcagcaac agtgccgcca ccggcagcac cgcgataggg agctgtaacg ccctaccgag
     4021 tcgctggaaa aaacctaaaa tattcatctt attcccccta cgagaaccct atttggctcg
     4081 tttaaagccg tatttttatt ttgctgcaaa ttgtactgcc gatgttctgt aatcagattg
     4141 ttagatcatc tgctacagag tgtgtgaaaa tttaattcgt atcgcaaatt aaacgcgtgt
     4201 cttttgtgag ttttgtcacc aaatatcgtt atcatcactc ccttttactg gctaaaccag
     4261 aaaacttatt ttatcattca aaaaatcagg tcggattgac gcctgtctgc gcaaatccag
     4321 gttacgctta aagatgccta atccgccaac ggcttacatt ttacttattg aggtgaataa
     4381 tgagactgat ccccctgact accgctgaac aggtcggtaa atgggctgct cgccatatcg
     4441 tcaatcgtat caatgcgttc aaaccgactg ccgatcgtcc gtttgttctg ggcctgccaa
     4501 ctggcggcac gccaatgacc acctataaag cgttagtcga aatgcataaa gcaggccagg
     4561 tcagctttaa gcacgttgtc accttcaaca tggacgaata tgtcggtctg ccgaaagagc
     4621 atccggaaag ctactacagc tttatgcacc gtaatttctt cgatcacgtt gatattccag
     4681 cagaaaacat caaccttctc aacggcaacg ccccggatat cgacgccgag tgccgccagt
     4741 atgaagaaaa aatccgttct tacggaaaaa ttcatctgtt tatgggcggt gtaggtaacg
     4801 acggtcatat tgcatttaac gaaccggcgt cttctctggc ttctcgtact cgtatcaaaa
     4861 ccctgactca tgacactcgc gtcgcgaact ctcgtttctt tgataacgat gtcaatcagg
     4921 tgccaaaata tgccctgact gtcggtgttg gtacattgct ggatgccgaa gaagtgatga
     4981 ttctggtgct gggtagccag aaagcactgg cactgcaggc cgccgttgaa ggttgcgtga
     5041 accacatgtg gaccatcagc tgtctgcaac tgcatccaaa agcgatcatg gtatgcgatg
     5101 aaccttccac catggagctg aaagttaaga ctttaagata tttcaatgaa ttagaagcag
     5161 aaaatatcaa aggtctgtaa ttgttatccc tgccctggct ccttgctcag ggcaatattt
     5221 tttaaaatcg ggggtcagaa tgtatgcatt aacccagggc cggatcttta ccggccacga
     5281 atttcttgat gaccacgcgg ttgttatcgc tgatggcctg attaaaagcg tctgtccggt
     5341 agcggaactg ccgccagaga tcgaacaacg ttcactgaac ggggccattc tctcccccgg
     5401 ttttatcgat gtgcagttaa acggctgcgg cggcgtacag tttaacgaca ccgctgaagc
     5461 ggtcagcgtg gaaacgctgg aaatcatgca gaacgccaat gagaaatcag gctgtactaa
     5521 ctatctgccg acgcttatca ccaccagcga tgagctgatg aaacagggcg tgcgcgttat
     5581 gcgcgagtac ctggcaaaac atccgaatca ggcgttaggt ctgcatctgg aaggtccgtg
     5641 gctgaatctg gtaaaaaaag gcacccataa tccgaatttt gtgcgtaagc ctgatgccgc
     5701 gctggtcgat ttcctgtgta agaacgccga cgtcattact aaagtgaccc tggcaccgga
     5761 aatggttcct gcagaagtca tcagcaaact ggcaaatgcc gggattgtgg tttctgccgg
     5821 tcactccaac gcgacgttga aagaagcgaa agccggtttc cgcgcgggga ttacctttgc
     5881 cacccatctg tacaacgcga tgccgtatat taccggtcgt gaaccgggcc tggcgggcgc
     5941 gatcctcgac gaagctgaca tttattgcgg tattatcgct gatggcctgc atgttgatta
     6001 cgccaacatt cgtaacgcta aacgcctgaa aggcgacaaa ctgtgtctgg ttaccgacgc
     6061 caccgcgcca gcaggtgcca acattgaaca gttcattttt gcgggtaaaa caatatacta
     6121 ccgtaacgga ctttgtgtgg atgagaacgg tacgttaagc ggttcatcct taaccatgat
     6181 tgaaggcgtg cgtaatctgg tcgaacattg cggtatcgca ctggatgaag tgctgcgtat
     6241 ggcgacgctc tatccggcgc gtgcgattgg cgttgagaaa cgtctcggca cactcgccgc
     6301 aggtaaagta gccaacctga ccgcattcac acctgatttt aaaatcacca ggaccatcgt
     6361 taacggtaac gaggtcgtaa ctcaataaga gaaagtatga caccaggcgg acaagctcag
     6421 ataggtaatg ttgatctcgt aaaacagctt aacagcgcgg cggtttatcg cctgattgac
     6481 cagtacgggc caatctcgcg gattcagatt gccgagcaaa gccagcttgc ccccgccagc
     6541 gtaaccaaaa ttacgcgtca gcttatcgaa cgcgggctga tcaaagaagt tgatcagcag
     6601 gcctccaccg ggggccgccg cgctatctct atcgtcaccg aaacccgcaa tttccacgca
     6661 atcggtgtac ggcttggtcg tcacgacgcc accattactc tgtttgatct cagcagcaaa
     6721 gtgctggcag aagaacatta cccgctgccg gaacgtaccc agcagacgct ggaacatgcc
     6781 ctgctgaatg ccattgctca gtttattgat agctaccaac gcaagctgcg cgagctgatc
     6841 gccatttccg tgatcctgcc tggacttgtt gacccggaca gcggcaaaat tcattacatg
     6901 ccgcatattc aggtggaaaa ctgggggctg gtagaagcac tggaagagcg ttttaaagtg
     6961 acctgtttcg ttggtcacga tatccgtagt ctggcgctgg cagagcacta cttcggtgca
     7021 agtcaggatt gcgaagactc cattttagtg cgtgtccatc gcggaaccgg ggccggaatc
     7081 atctctaacg ggcgcatttt tattggccgc aacggcaacg tcggtgaaat tggccatatt
     7141 caggtcgaac cgctgggtga acgctgccac tgcggcaact ttggctgcct ggaaactatc
     7201 gccgccaacg ctgccattga acaacgggtg ttgaatctgt taaagcaggg ctaccagagc
     7261 cgcgtgccgc tggacgactg caccatcaaa actatctgca aagccgcgaa caaaggcgat
     7321 agtctggcgt cggaagtaat tgagtatgtc ggtcgtcatc tgggtaaaac catcgccatt
     7381 gctatcaact tatttaatcc gcaaaaaatt gttattgccg gtgaaatcac cgaagccgat
     7441 aaagtgctgc tccctgctat tgaaagctgc attaataccc aggcgctgaa ggcgtttcgc
     7501 actaatctgc cggtggtacg ttctgagctg gatcaccgct cggcaatcgg cgcttttgcg
     7561 ctggtaaaac gcgccatgct caacggtatt ttgctccagc atttgctgga aaattaatgt
     7621 gcttttatag tggcgcttat tgttgtcaat attctgggta gtccatgacc attaaaaatg
     7681 taatttgcga tatcgacggc gtgctgatgc acgataacgt cgccgtaccg ggtgcagcgg
     7741 aatttttgca cgggattatg gataaaggcc tgccgctggt gttgctgacc aactatcctt
     7801 cgcagactgg gcaagatctg gcgaaccgct ttgccaccgc aggtgtcgat gtacctgaca
     7861 gcgtgtttta tacctctgcg atggcgactg ccgatttcct gcgtcgccag gaaggcaaga
     7921 aagcgtatgt ggtgggcgaa ggcgcactga ttcatgaact gtacaaagcc ggtttcacta
     7981 ttaccgatgt gaaccctgat ttcgtgattg ttggcgaaac gcgttcctac aactgggaca
     8041 tgatgcataa agcagcctat ttcgtcgcta acggtgcacg ttttatcgcc accaatccgg
     8101 acacccacgg gcgcggtttt tatcccgctt gtggcgcgtt gtgtgcaggg attgagaaaa
     8161 tctccgggcg caaaccgttc tatgttggta agcccagccc gtggatcatc cgcgcagcat
     8221 taaacaaaat gcaggcgcat tcggaagaaa cggtgattgt cggcgataac ctgcgtaccg
     8281 atattctggc cggcttccag gcaggtctgg agacgattct ggtgctttct ggtgtttcgt
     8341 cgctcgacga tatcgacagt atgcctttcc gccccagctg gatttacccg tcagtcgctg
     8401 aaatcgacgt tatctgaata gcaaccacgt ctgcggacgt ggttggctct gatgacaaac
     8461 gccaaactgc ctgatgcgct acgcttatca ggcctacgca gctcctgcaa tatattgaat
     8521 tttcatgctt ttgtaggccg gataaggcgt tcacgccgca tccggcatga acaaatcgca
     8581 ctttgtcagc aatttggccc ccgtaaaata taaacattca ataaaacccg ctaa
//
LOCUS       DAPHKZ010000164         8615 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.165, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000164 DAPHKZ010000000
VERSION     DAPHKZ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8615
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.165"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(109..1752)
                     /gene="yeeO"
                     /locus_tag="RH288_004127"
     CDS             complement(109..1752)
                     /gene="yeeO"
                     /locus_tag="RH288_004127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416491.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic metabolite efflux MATE transporter YeeO"
                     /protein_id="HDV4033122.1"
                     /translation="MLRHILTAKNLLSNPIFKFPNCLPFLSTVCCICRQFVGENLCSF
                     ADSPSLFEMWFHFLQLRSALNISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIF
                     MENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLG
                     KRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYLEL
                     TVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWPGLGFV
                     GAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIGIPASVE
                     SVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVG
                     QIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAGLMASFYTQDPQVKHVVVILIWLNALF
                     MPIWSASWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMF
                     ADWAVRAVLFYWRMVTGRWLWKYPRPEPQKCEKKPVVSE"
     gene            1757..1832
                     /locus_tag="RH288_004128"
     tRNA            1757..1832
                     /locus_tag="RH288_004128"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1790..1792,aa:Asn,seq:gtt)
     gene            complement(1870..2820)
                     /gene="cbl"
                     /locus_tag="RH288_004129"
     CDS             complement(1870..2820)
                     /gene="cbl"
                     /locus_tag="RH288_004129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator Cbl"
                     /protein_id="HDV4033123.1"
                     /translation="MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL
                     GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT
                     QARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVA
                     FPWFRWHHSLLVPLDHPLTQITPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLPA
                     DIVLSAQDSDVIKTYVALGLGIGLVAEQSSGAQEEENLIRLDTRHLFDANTVWLGLKR
                     GQLQRNYVWRFLELCNAGLSVEDIKRQVMENSEEEIDYQI"
     gene            complement(2922..3839)
                     /gene="nac"
                     /locus_tag="RH288_004130"
     CDS             complement(2922..3839)
                     /gene="nac"
                     /locus_tag="RH288_004130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen assimilation transcriptional regulator
                     NAC"
                     /protein_id="HDV4033124.1"
                     /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELN
                     QQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQSLSGQVSIGFAPGTA
                     ASSITMPLLQAVRAEFPEVVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA
                     LLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAVRLRVDEAFSLRRLTAKVIGE
                     IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL
                     SPQAQAVKELLMSVMSSPVMEKRQWQLVS"
     gene            4165..4240
                     /locus_tag="RH288_004131"
     tRNA            4165..4240
                     /locus_tag="RH288_004131"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4198..4200,aa:Asn,seq:gtt)
     gene            complement(4296..5231)
                     /gene="ldtA"
                     /locus_tag="RH288_004132"
     CDS             complement(4296..5231)
                     /gene="ldtA"
                     /locus_tag="RH288_004132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDV4033125.1"
                     /translation="MMRRVNILCSFALLFASHTSLAVTYPLPPEGSRLVGQSFTVTVP
                     DHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKSGSQLTIPQQLILPATVRKGIVVN
                     VAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYA
                     KRGESLPAFVPAGPDNPMGLYAIYIGRLYAIHGTNANFGIGLRVSQGCIRLRNDDIKY
                     LFDNVPVGTRVQIIDQPVKYTTEPDGSNWLEVHEPLSRNRAEYESDRKVPLPVTPSLR
                     AFINGQEVDVNRANAALQRRSGMPVQISSGSRQMF"
     gene            complement(5293..6372)
                     /gene="cobT"
                     /locus_tag="RH288_004133"
     CDS             complement(5293..6372)
                     /gene="cobT"
                     /locus_tag="RH288_004133"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDV4033126.1"
                     /translation="MQILADLLNTIPAIDSAAMSRAQRHIDGLLKPVGSLGKLEALAI
                     QLAGMPRLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL
                     AEQAGANVHVIDVGIDTAEPIPGLINMRVARGSDNIASAPAMSRRQAEKLLLDVICYT
                     QELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVV
                     RRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAAC
                     QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLDMEMRLGEGSGAALAMPIIEAACA
                     IYNNMGELAASNIILPGNTTSDLNS"
     gene            complement(6384..7127)
                     /gene="cobS"
                     /locus_tag="RH288_004134"
     CDS             complement(6384..7127)
                     /gene="cobS"
                     /locus_tag="RH288_004134"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDV4033127.1"
                     /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL
                     GAISGLVFMVLQAWCGAPLATLFSVLVLVLMTGGFHLDGLADTCDGVFSARSRDRMLE
                     IMRDSRLGTHGGLALIFVVLAKILVLSELALRGESILASLAAACAVSRGTAALLMYRH
                     RYAREEGLGNVFIGKIDGRQTCVTLSLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL
                     LKRTLGGQTGDTLGAAIELGELVFLLALL"
     gene            complement(7124..7669)
                     /gene="cobU"
                     /locus_tag="RH288_004135"
     CDS             complement(7124..7669)
                     /gene="cobU"
                     /locus_tag="RH288_004135"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDV4033128.1"
                     /translation="MMILVTGGARSGKSRHAEVLIGDSSQVLYIATSQILDDEMAARI
                     EHHRQGRPEHWRTVERWQHLDELIHADINPNEAVLLECVTTMVTNLLFDYGGDKDPDE
                     WDYHAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
                     QLAAAANEVWLVVSGIGVKIK"
BASE COUNT         2392 a         2307 c         1852 g         2064 t
ORIGIN      
        1 acagaggaat cgtgagaacg aggcgaatat tagcgatgcc cacccacaat gtcaaagcct
       61 gttttttaaa tttgaaatcg tttgctgaaa taatctgcat tttgtcgttt attccgacac
      121 aactggcttt ttttcacact tttgcggctc gggtcgaggg tatttccata gccaacgtcc
      181 agtaaccatt cgccagtaaa acagcacggc ccgcacagcc cagtcggcaa acattcccat
      241 ccagacacca accacacccc agccaagcat gattcccagc acataaccga ctacaacccg
      301 acaaccccac atgctcaaca tcgaaaccca catggcgtaa cgggcatcac gagcaccttt
      361 aaatccagcg ggtagcaccc atgaggcgga ccaaataggc ataaataaag catttagcca
      421 aatcagaatc acaacgacat gtttaacctg tggatcctgg gtgtaaaacg atgccataag
      481 cccggcaaag ggagccgtta gccaggcgat ggccgttaat ccaagagtgg acagccagaa
      541 cacatgccgc aactgaatct ctgcttgcgc tatctgccct acccccaacc ttcggcctgt
      601 aatgatcgta gaagcagagc cgagcgcact tccgggtaag ttgataagag ccgcaattga
      661 aaacgcgata aaatttccgg caataacact ggtccccatc ccggcaacga acatttgggt
      721 taataaccga ccactggtaa ataacactga ttcgacactc gctggaatac caatccccat
      781 gacttcccag ataatgctaa aattcagcgg tttaaaatag ctctttaacg aaatccttag
      841 cgcaggatta aaaccaatcg ccagcaccca caaaattgca actgcgccaa tataacgaga
      901 aatggttaaa cccaacccag ccccgacaaa tcccagtccc ggccaggaga aaaggccgta
      961 aatcaatatg ccgctaataa taatattaag aatattcagg ctaccgttaa tcagtagcgg
     1021 tattttcgta ttccctgcac cacgaagtgc cccgctacca attagagtga tggcagctgc
     1081 tggataactg agtaccgtca gctccagata agtcaacgcc agtgctttaa cttctgtcgt
     1141 ggcatcaccc gcgacgaaat caataatttg ctcgccaaaa tgatgaataa gcgttgccaa
     1201 cagtacggca aacaacgtca tgatcaccaa tgactgccgc gtcgccaccc tcgctcgtcg
     1261 tcgatcccgc ttaccgagac taaatgccac aacgacagta gtaccaagat cgatagcagc
     1321 aaaaaaagcc ataatgacca tattgaagct gtccgccaat cccacgccgg ccatcgcatc
     1381 ttttcccagc cagctgacca gaaaagtgct cagaaccccc atcaacagga cacaggcatt
     1441 ctccatgaag ataggaacag caagcggggt tatctcgcgc cagaacaaca ctttgtagct
     1501 cttgcgttta gcgtgccagc gagtgccgtg aacaacctga cgtaaagcag aggagatatt
     1561 caaagccgac cttaattgca gaaagtgaaa ccacatttca aataatgagg gagaatcagc
     1621 aaagctgcaa agattttcgc caacaaattg tctgcaaatg caacaaactg ttgatagaaa
     1681 cggcaaacag ttggggaatt taaaaatcgg gtttgacaaa agatttttcg ccgttaagat
     1741 gtgcctcaac agcgattcct ctgtagttca gtcggtagaa cggcggactg ttaatccgta
     1801 tgtcactggt tcgagtccag tcagaggagc caaatttctg aaaagcccgc ttttatagcg
     1861 ggctttttgc tatatctgat aatcaatttc ctcttcactg ttttccatca cctggcgctt
     1921 gatatcctca actgacagtc ctgcattaca aagttccaga aagcgccaga catagttacg
     1981 ctgaagttgt cctcgcttca gtcccaacca gacagtatta gcatcgaaaa gatgccgcgt
     2041 atccaggcgg attaaattct cttcctcttg tgcgccgctg gattgttcgg caactaatcc
     2101 gatcccaagc ccaagagcaa cataggtttt aatgacatca gaatcctgtg cacttaatac
     2161 aatatctgcc ggcaaacctt tgcgggcaaa tgcgtcatca atacgtgagc gccccgtaat
     2221 cccctgtcgg taagtgatta acggccactt cgctattgat tccagcgtca acggtgtaat
     2281 ttgcgtcaag ggatgatcga gtggaacaag caaactatgg tgccaacgaa accacgggaa
     2341 ggcgacgagc tgcgggtcat tactcaaacg ctcgctggcg ataccaatat cagcttcgcc
     2401 attttgcaac aacgtcgcaa tttcctgtgg cgtaccctgg attagctcca gccgaacctc
     2461 cgggaaaagt tcgcgaaaag ctttaatgac ctcaggcaag ctataacgtg cctgagtatg
     2521 cgttgttgca atagtgagaa cgccagacgt atcgttggta aacaggtctg caagccgacg
     2581 aacattactg gcttcattca gaatacgttc tgcaatgacc agtaatgctt tgcccggttc
     2641 agtcatgccc agcagtcgct tacctcgtcg aacaaatatt tcgatgccaa gttcatcctc
     2701 cagttcccga atatgacggc tgacgccgga ctgtgaggta aaaagcatat tcgcaacctc
     2761 tgtcaggttg taatcctgac gtgcagcctc gcggattatc tttagttgtt ggaaattcac
     2821 ggtaaactcc gggcagttca gattttccgt cattgttaaa gtctaatgcc cggcataaca
     2881 aataataaaa acccgcatct tattccatcc cgatataacg cttagctcac caattgccac
     2941 tgcctttttt ccatcactgg agaactcatc actgacatta acaactcttt cactgcctgt
     3001 gcctgtggtg ataagttcgc tctggcgggt aaatttaatg acaaagagag actcatggaa
     3061 ggtgtggtaa tgcgtgacat ccacccgttt actgcgccac ataacgaacg cgcggccgat
     3121 tcgggtaata ctgcaacgcc catgccgctg gcaatcgctg cggtaagcgt ggcaattgac
     3181 tcaatttcac caatgacttt tgccgtgagt cgccgtaggg aaaaagcctc atcaacacga
     3241 agtctaacag cactgtaatc actgggaaga aagaggttca tttgcgcaat agcattaaca
     3301 tcaacgcttt gccccggaca atcttgagtc cctaccagga aaagatcttc tttcagtaaa
     3361 gcctgactgg atacaccagc cacaggggaa tgctcataaa tcaccgccat atcgagttgg
     3421 tgatttatca gtttttcgtt aagcactgca ccactatttt catgaagata gataacgacc
     3481 tccgggaatt cagcgcgaac cgcctgtaat aagggcatgg tgatggatga cgcagcggtt
     3541 cctggcgcaa agccaatcga gacttgcccc gataatgact gaccaacgtt atgcaccgcc
     3601 agttgggcct gctcacactg acgtaaaatg gcccgcgcat gggtatagag aatttttccg
     3661 gcgtctgttg gcgtaacgcc ccgttttgtg cgaatcaaaa gttgttgatt taactcacct
     3721 tccagtgtgg caacctgctg gctgagcgct ggttgtgcga tatgcaatac ttcagcagcc
     3781 tgagtcaggc taccaatatc tacaattttt acgaagtatt tcaggcgtct gaagttcatg
     3841 ttgcctccgg tttttgagaa tcggcccaag tgccgccatt acttacaacc agactgcaag
     3901 atgcttgcca gttttatttt ggcgttgatg tacaagctaa ccaactgtca aataagagat
     3961 tatgatagat tcgtcattgg ctcttttcac cagcagtcgc gttcccctgc cctataaaag
     4021 gagggtatgc accacgatgg ttcattacca ataagattga aatctcatca ctttgttgaa
     4081 attgacagca aacaaacaaa aaaatgcatt tcaccctttg acatcaccat gcactgccat
     4141 taatatgcgc cccgttcaca cgattcctct gtagttcagt cggtagaacg gcggactgtt
     4201 aatccgtatg tcactggttc gagtccagtc agaggagcca aattcaaaaa agcctgcttt
     4261 ctagcaggct ttttgctttc taattactaa cgctcttaaa acatctgtct tgaaccagaa
     4321 ctaatttgca caggcattcc cgatcgacgt tgcaacgcag catttgcgcg attcacatca
     4381 acttcttgcc cgttgataaa cgcccgcaaa gatggggtta ccggcaatgg cacttttcgg
     4441 tcagactcat attctgcacg attgcgcgac agcggctcat gaacttccag ccagttcgag
     4501 ccatctggtt cagtggtgta ttttactggc tggtcgataa tttgcacacg cgttccaaca
     4561 ggaacattat caaacagata tttgatatcg tcattgcgca gacgaataca gccctgactt
     4621 acccgaagtc caataccaaa attggcattg gtaccgtgga tggcatacaa cctgccaata
     4681 taaatcgcgt acagccccat gggattatcg ggccccgcag gaacaaatgc gggcaaactc
     4741 tcccctcgtt tcgcatattc gcgccgagtg ttcggcgttg gcgtccaggt tggagcttct
     4801 tgtttacgtt caacggtagt cacccagtta cgcggggttt ctcgcccagc ctggccgata
     4861 ccaataggaa agacttccac agtattactg tctggtgggt agtaataaag acgcatctca
     4921 gcgacgttaa ccacaatccc tttacgaaca gtggcgggca aaatcagttg ctgcggaatg
     4981 gtgagttgcg agccagactt cggcaagaaa acatcagcgc ccgggttcgc ttccagcatg
     5041 ttacttaacc cttgcccgta ttgtgcggca aaagtctcca gcggctgggt attgtgatca
     5101 ggaacagtta cagtaaacga ctgccccact aaacggctac cctctggagg taatggataa
     5161 gttaccgcca ggctagtatg gctggcaaaa agcagagcaa atgagcaaag aatatttaca
     5221 cgacgcatca tgtccctttc ctaagtcgcg aaagctatcc gttaagtata gcttttatca
     5281 gacttttcgt ttttaactgt tcaaatcaga agtcgtattc cccggtagaa taatattact
     5341 ggcagcaagt tcacccatgt tgttatatat cgcacaggca gcttcgatga tgggcatcgc
     5401 cagagctgcg ccactcccct cacctaaacg catctccata tcgagataag gctccagccc
     5461 caaatgcgac agcgctatac gcgcgccttt ttctgccgac aagtgagaag gaatgagata
     5521 cggtttgatt gcaggagaca tctggcaggc tgcgagcgca gcagcataag aaagaaatcc
     5581 atccagcaac acgggtaaac cgcaggaagc agcacctaac atcactccag ctattccgac
     5641 caaatcaaat ccacccactt ttgccaggac atcaacacca tcctgaggat ttggttgatt
     5701 caacgtaatc gcccgacgca caacatcaat tttattagcc agtttatctg tcggcaggtt
     5761 tgcgccaatc ccaaccactt cttcaggatc ccggccagtg attgtgctga ctattgctgc
     5821 tgccggtgtc gtgtttgcca tccccagttc acctacacca aacagcgtga caccgttttt
     5881 tgccagctcc tgcgtataac atatgacgtc caaaagcaac ttttcagcct gacggcgact
     5941 cattgccgga gctgaagcaa tattgtcgct acctcgtgcg acacgcatgt tgataagccc
     6001 ggggataggc tcagcagtat caataccaac atcaattacg tggacgttag cgcccgcttg
     6061 ttctgccagc acacacacgc cggttgttcc acgggtcata ttttcagcct gtatggctgt
     6121 cacttctttt ggagaaatag cgaccccttc ctcccagacg ccgtgatcgg cacacataac
     6181 cagtaccgct tttttgccca catgcggtat gccattcaac ctcggcattc ctgccagttg
     6241 tatggcaagc gcctccagct ttcccaggct accaacaggt ttgagtaacc cgtcaatatg
     6301 ccgttgtgca cgcgacatag cggcagaatc gatggctggg atcgtattca gtaaatcggc
     6361 aagtatttgc atgtcacgtc tctttatagc agtgccagca ggaagaccag ttcaccaagc
     6421 tctatggctg ctcccagcgt atcgcccgtt tgcccgccca gcgtacgttt gagaagctga
     6481 ccgaggatga aaatcgccac catcgtcacc accatagcag ccacaccatg catacccggc
     6541 aataatacgg cagcaaaaat agcggctaag ctgagtgtga cgcaggtttg tcgcccatca
     6601 attttgccaa tgaacacatt gccaagccct tcttcccgcg cataacgatg acgatacatc
     6661 aataatgcgg cagtcccgcg gctgaccgca catgctgccg ccagcgatgc aaggatcgat
     6721 tcgccacgca gagccaactc gcttaacacc agaatctttg ccagtaccac aaaaatcaat
     6781 gccagaccgc cgtgggtgcc taaacggcta tcacgcatga tttccaacat gcgatcgcgg
     6841 ctacgtgcag aaaatacgcc atcacaggta tcagcgaggc cgtccagatg gaatcccccg
     6901 gtcatcagca ccagcacaag tacgctaaac agtgtcgcca gtggtgcgcc acaccatgcc
     6961 tgcagcacca tgaagaccag cccgctaatc gcgccaagca ataatccaat caaaggaaaa
     7021 gtaataatac cacgagaata atgctcgaaa tccagtccct gggaccagcg acgcggtaca
     7081 ggcagacgcg taataaatga gagcatcgcc caaaataatt tactcatttg atttttactc
     7141 caatacccga aaccaccagc catacttcat ttgccgcagc ggccaactgc tgatttaccc
     7201 gcccggcaat atcacgaaaa tgtcgtgcca gacgactctc cggcacaatc cccattccca
     7261 cttcgttagt cactaataca acctttgcgg ggcaacgttg gcaggcagca atcaacgact
     7321 gaatctcagc attaatcgcc tgttccatcg cgtgataatc ccattcatca gggtctttat
     7381 cgccgccata atcaaacaac agattagtca ccattgtggt aacgcattcc agcaacacag
     7441 cctcattcgg gttaatgtct gcatgaatta attcatcaag atgttgccag cgctccactg
     7501 tgcgccagtg ctccgggcgg ccttgccgat gatgttctat ccgtgcagcc atctcatcat
     7561 caaggatttg cgaggtagcg atatacagaa cctgtgaaga gtccccaata agcacctctg
     7621 cgtggcgact cttcccgctc cgtgcgcccc ccgtcaccaa aatcatcata ccgactcctg
     7681 attcaaatgt atgatggtat tcattgaaca gaacaatgga tcccccaccg ttgctgaccg
     7741 caaaacattt acgcgattaa tactgcgcgt aatataatta aaaatccagc attctcaatc
     7801 cattacgaaa taagatggca ttacggaata gccaaacttt ctcgtgttaa cgtccgacaa
     7861 aatgcgtcat tgacagcggt ttctgtggat tgacacattt cattcagata atgaattaat
     7921 gctactgccg gaccaaccag caaacaggca ttgtgttctg aaatccaggc tattgattca
     7981 acgtcagcga cagatctgcg ctgtaaaaga acttgtaaaa caacgcaata gaattatccg
     8041 gaatggtggc gactatgcac tagaacacca caatttcgct ctctcggtaa ggcactgtca
     8101 cagcattcaa cagaatgtga cctgccagat ttattagcgc caccagatgt ttaaccgggt
     8161 aaccacgacc cagtcgggga tatattccat cttctcgctg acatcatcaa gaataaaaag
     8221 gtttatcaca ctcagagcaa cgttcttcag caggcgggat aattcttcaa catttagaag
     8281 atgtgttatt aaaggcatac aaactggacg tattgtattt tcttttggtg gttgacctaa
     8341 ggtagcagtt tatcctgatg cgctgagatt tctgtaatat ctacgtcaac attctcctcg
     8401 aatagaaaat gcagccccgg caagtgattc acatttttta acaaaacgtt gttagcgtgc
     8461 cattttcaga agctctccaa gaaagctaat tcttttctca aattctgcat tctcagacac
     8521 agctttctac tccatggcaa tggcccaaat acgaagttgc tcaggatcat tagtggtgct
     8581 gagaagttaa ataaccatgc ggagtaccac tcgtc
//
LOCUS       DAPHKZ010000165         8605 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.166, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000165 DAPHKZ010000000
VERSION     DAPHKZ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8605
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.166"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..517
                     /locus_tag="RH288_004136"
     CDS             <1..517
                     /locus_tag="RH288_004136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SopA family protein"
                     /protein_id="HDV4033129.1"
                     /translation="SKVNFDTQQMIDFINRFNMNKWLIDKNNNFFIQLIDQALRSTDD
                     MIKANAWHLYKEWIRSDDVSPIFIETEDNLRTFNTNELTRNDNIFILFSSVDDGPVMV
                     VSSQRLHDMLNPTKDTNWNSTYIYKSRHEMLPVNLTPETLFGSKSQDKHALFPIFTAS
                     WRANRIKNKGI"
     gene            740..1237
                     /gene="ubiC"
                     /locus_tag="RH288_004137"
     CDS             740..1237
                     /gene="ubiC"
                     /locus_tag="RH288_004137"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HDV4033130.1"
                     /translation="MSHPALTQLRALRYCKEIPALDPQLLDWLLLEDSMTKRFEQQGK
                     TVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSG
                     PELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            1250..2122
                     /gene="ubiA"
                     /locus_tag="RH288_004138"
     CDS             1250..2122
                     /gene="ubiA"
                     /locus_tag="RH288_004138"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HDV4033131.1"
                     /translation="MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTFWALWVATPGVP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVV
                     LVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL
                     QIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(2277..4700)
                     /gene="plsB"
                     /locus_tag="RH288_004139"
     CDS             complement(2277..4700)
                     /gene="plsB"
                     /locus_tag="RH288_004139"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418465.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HDV4033132.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESI
                     KLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
                     RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDST
                     VPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMA
                     AIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQ
                     DDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLT
                     IESATQGEG"
     gene            4871..5239
                     /gene="dgkA"
                     /locus_tag="RH288_004140"
     CDS             4871..5239
                     /gene="dgkA"
                     /locus_tag="RH288_004140"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDV4033133.1"
                     /translation="MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVV
                     IACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LIAIIVAVITWCILLWSHFG"
     gene            5349..5957
                     /gene="lexA"
                     /locus_tag="RH288_004141"
     CDS             5349..5957
                     /gene="lexA"
                     /locus_tag="RH288_004141"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HDV4033134.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL"
     gene            6030..7355
                     /gene="dinF"
                     /locus_tag="RH288_004142"
     CDS             6030..7355
                     /gene="dinF"
                     /locus_tag="RH288_004142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HDV4033135.1"
                     /translation="MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVY
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGAL
                     IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGI
                     SGEMLKTAWRGNFRRLLALNRDIMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGE
                     HIIALLTSLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAA
                     GFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT"
     gene            7471..7680
                     /locus_tag="RH288_004143"
     CDS             7471..7680
                     /locus_tag="RH288_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDV4033136.1"
                     /translation="MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVVDWETRNEYRW"
     gene            complement(7722..8237)
                     /gene="zur"
                     /locus_tag="RH288_004144"
     CDS             complement(7722..8237)
                     /gene="zur"
                     /locus_tag="RH288_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418470.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HDV4033137.1"
                     /translation="MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISA
                     YDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFI
                     CDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
                     DHSVQVKKKPR"
BASE COUNT         2004 a         2067 c         2316 g         2218 t
ORIGIN      
        1 cagtaaggtg aatttcgata cccaacaaat gatcgatttt attaacagat ttaatatgaa
       61 taaatggctg attgataaaa ataacaattt ttttatccaa cttatcgatc aggccttacg
      121 atcaacggat gatatgatca aagcaaatgc ctggcatctt tataaagagt ggattcgtag
      181 tgatgatgtt tcacctatat ttatagaaac tgaagataat ttaagaacct ttaacacgaa
      241 tgaattaaca cgaaacgata atatctttat cctgttctcc tctgtcgatg atgggccagt
      301 tatggtggta agctcccagc gcttacatga tatgttgaat cctacaaaag ataccaattg
      361 gaattccacg tatatctaca aatccagaca tgagatgttg cctgttaatc ttactccgga
      421 aacacttttc ggctctaaat ctcaggataa acatgcgctt ttccccattt ttactgcgag
      481 ttggcgagct aatcgtataa agaataaagg tatttaagta aaggaaaaca tcaccgttcc
      541 tggcatcctg ggcggtgatg cccctatggt tgccctctcc agcgcgggca tcggcaaagc
      601 gtaaggttca acagcgtttt accacttcat gcgattgttg cgtttttgtt gcgtattaga
      661 tcacttaatt tgctttacat ctcccgtaaa cacttttctg cgatacaatg cctttacgtt
      721 atgtaacgga gagttcggca tgtcacaccc cgcgttaacg caactgcgtg cgctgcgcta
      781 ttgtaaagag atccctgccc tggatccgca actgctcgac tggctgttgc tggaagattc
      841 catgacaaaa cgttttgaac agcagggaaa aacggtgagc gtgacgatga tccgcgaagg
      901 gtttgtcgag cagaatgaaa tccccgaaga actgccgctg ctgccgaaag agtctcgtta
      961 ctggttacgt gaaattttgt tatgtgccga tggtgaaccg tggcttgccg gtcgtaccgt
     1021 cgttcctgtg tcaacgttaa gcgggccgga gctggcgtta caaaaattgg gtaaaacgcc
     1081 gttaggacgc tatctgttca catcatcgac attaacccgg gactttattg agataggccg
     1141 tgatgccgga ctgtgggggc gacgttcccg tctgcgatta agcggtaaac cgctgttgct
     1201 aacagaactg tttttaccgg cgtcaccgtt gtactaagag gaaaaaaata tggagtggag
     1261 tctgacgcag aataagctgc tggcgtttca tcgcttaatg cgtacggata agccaattgg
     1321 cgcgttactg ctgctctggc caacattctg ggcgttgtgg gtggcgacac cgggcgttcc
     1381 ccagctctgg atcctggcgg tgtttgtcgc gggtgtctgg ctgatgcgcg ctgccggatg
     1441 tgtggtgaat gattatgctg accgcaagtt tgatggtcat gttaagcgca ctgcgaaccg
     1501 accacttccc agcggcgcgg taacagagaa agaggcgcgc gcgctgtttg tagtgctggt
     1561 actgatttcg tttttactgg tgctgacgct gaatacgatg accattctgt tgtcgattgc
     1621 cgcgctagcg ctggcgtggg tgtacccgtt tatgaagcgg tatacccatc taccgcaagt
     1681 ggtgctgggc gcggcgtttg gctggtcgat tccaatggct tttgccgctg tgagtgagtc
     1741 ggtgccattg agttgctggt taatgttcct cgccaatatt ctctgggcgg tggcttacga
     1801 cacgcagtat gcgatggttg accgcgatga tgatgtgaag attggcatta aatccacggc
     1861 aatcctgttc ggccaatacg ataaattgat tattggtatt ttgcagattg gcgtactggc
     1921 gctgatggcg atcatcggtg agttaaatgg cttaggctgg ggatattact ggtcaattct
     1981 ggtggctggc gcgctgtttg tttatcaaca aaaactgatt gccaaccgcg agcgtgaagc
     2041 ctgctttaaa gcatttatga ataataacta tgttggtctg gtactgtttt tagggctggc
     2101 aatgagttac tggcatttct gatgatgtaa aaaagccgga tgatcatccg gctttcttct
     2161 ggggtgcctg atgcgctgcg cttctcaggc ctacacaaca gatcgcaatt tattgaattt
     2221 gcagattatg gtaagccgga taaggcgttt gcgccgcatc cggcaattct cactgattac
     2281 ccttcgccct gcgtcgcact ctcaatcgtc aaacgcacgt ctgatgtaat caactccgcc
     2341 agcaactgat aaaccttcat cgtttctgcc ggttcggcat cgccgctatc gctgatatac
     2401 ccttcatcac gcagcgtcag caccagagaa ctgaacaccg ccttgtcgaa gaactccggc
     2461 gcgttgatac cgtgcagcac ggagagacgt tgcgcgacgg tgcggctctc tttctccagc
     2521 gtaccgcggt tgatcgacgg gttggcgctc aacagccaga aggtgatggc ataacgttgc
     2581 agcgtttcgc gcgcgcctgc ggcgagcagc tgtagcgtgc gagaatgcgc cgggttgata
     2641 tgcaactcat catcttgcag ggtaatcagc ccctgacgtt gcatctcatt tgccagcgca
     2701 tcaataacgt ccggcaactc gtcgcgatcc cagcgcagga acagctccgc tttcagcatt
     2761 gggtaaagca cattgacgtg ctccatcaat acgtcgcggg agatgtggcg atgctgggtg
     2821 acaattgccg ccatcagcga aggcagcacc aacatatgcg caatgttgtt gcgatagtag
     2881 gtcatcaaca ccgcttgctc gcgcggcaga atgatgatgt cgccgatagt gtctttctcg
     2941 acttcaaact tgttcatttg cagcgcgtga tcgataagct cgctggcgct ggctgaagga
     3001 acggtagagt ccgtggagta aggtacgttg cgcatcagat ccaggtagca gttgagttgc
     3061 tcggttaact gctcgcgggt gagtgagcgc tgacgtgacg ccagtagcgc agtacagcac
     3121 aggttcatgg cgtttgccgc gcctgcgttg ttaatgcgta ccatcagatc ggcagcaata
     3181 ttattgaccg tcggcgttaa ccaggccgga cgcaccgctt cgatgggatc gatagattca
     3241 cgccagtctg gtacgtgctg gttaaggtag gtcatcaacg gcattggttc accgaaattg
     3301 acgtaaccct ggccgagatt acgcagcttg cttaaaccgc gcagcatctg cggcaggctc
     3361 tctttctctt tcgtcgcacc gcgcagttct ttggcgtaag tacccacttc catgacgtgc
     3421 tcataaccga tatagatcgg aatcagcgta atcggacgcg tgccgccacg cagcatcgcc
     3481 tgaatggtca tcgacagcgt accggttttc ggatccagca aacgccccgt acgggaacga
     3541 ccgccttcca cgaagtactc gacggaataa ccacggctga acagttcgcc gagatactca
     3601 cggaaaacgg tggaatagag cttattgcct ttaaaagtac ggcgaataaa gaacgcaccc
     3661 agacggcgga aaatcggccc ggccggccag aagttcaggt tgatcccggc ggcgatatgc
     3721 ggcggcacca gcccctggtg gtacagcacg taagaaagca gcaggtagtc catgtgactg
     3781 cggtggcaag gcacatatac cagctcatga ccgtcgtggg ccagctggcg aacgcgctcg
     3841 gcgttatgga cgttgatgcc ctggtaaagg cggttccagg taaagcccag aatacggtca
     3901 gtcaggcgga tcatctcgta agagaaattc gccgcaatct cttccatcag cgcaatcgcg
     3961 ttctgctgcg ctttttcatg ggagattttt ttgctgcgcg cttcatcttc taccgctttc
     4021 gcaatagcgc gggaggcgag cagcttatta aacagatcct gacgagcagg cagacgtggg
     4081 cctacggcag ccagacgttg acgggcaaag tgcatacgcg ccacgcgcgc cagtttctgc
     4141 gcgatagttt tatccgtgcc gtgttcatcc gccatacggc gcagcgaaac tgacggcgag
     4201 aaacgcacaa aactgtcgcg accgagccac agtacagcga aaaatttctg tacgccgtta
     4261 agcatacgca gcggcgggtt cacttcgcct ttttcacgcc ctggcgcgcg accaaacatc
     4321 accgatactg gcaccatctg cacatccaga tttgggttgc tacggtgcaa atcgagatag
     4381 tcgtggaaca gcttaataga ctcttctttc ggcgtgtaat aggtgaatac acgcggcccg
     4441 ccgtgaatga acacatagcg cggcagtagc gtgccgtcga tttccagcgg ctctaacggg
     4501 tcaggcaggt catgtgccag acactgggcg cgcaacgtca gcaaatctgc tttcgagttg
     4561 tacggtaaaa cgtacataat tggacgagag gtatccagcc ccagttccgg ggcaggatct
     4621 gccggaatag acttgctttt taccaggatg cttaatggta aattcagtaa tttgtagtaa
     4681 attcgtggcc agccggacat aaacgatgta aagcctctgg ttaataatgc aaatgcgcgg
     4741 caaggatagc agaaagtcat gggaaattct gtggtatccg ctcatgtttc gcgcggcgtt
     4801 acgcaaaccc gaatcatcgg atttaacggt acactgatat tgacgctcat aatgtaaaaa
     4861 ggttctttca atggccaata ataccactgg attcacccga attatcaaag ctgctggcta
     4921 ttcctggaaa ggtttacgcg ctgcatggat caacgaagcg gcattccgtc aggaaggcgt
     4981 agcggtattg ttggcggtgg tcatcgcctg ctggctggat gtggacgcaa ttacccgcgt
     5041 gctgcttatc agctccgtga tgctggtgat gattgtggaa atcctcaata gcgccatcga
     5101 agcagtggtt gaccgaattg gctctgaata ccatgagctt tccggacgcg ctaaagatat
     5161 gggatccgcc gcggtgctga ttgcgattat cgtcgccgtg ataacctggt gcatcctgtt
     5221 atggtcgcat tttggataac ccttccagat ttcgataaat ctctggttta ttgtgcagtt
     5281 tatggttcca aaatcgcctt ttgctgtata tactcacagc ataactgtat atacacccag
     5341 ggggcggaat gaaagcgtta acggccaggc aacaagaggt gtttgatctc atccgtgatc
     5401 acatcagcca gacaggtatg ccgccgacgc gtgcggaaat cgcgcagcgt ttggggttcc
     5461 gttccccaaa cgcggctgaa gaacatctga aggcgctggc acgcaaaggc gttattgaaa
     5521 ttgtttccgg cgcatcacgc gggattcgtc tgttgcagga agaggaagaa gggttgccgc
     5581 tggtaggtcg tgtggctgcc ggtgaaccgc ttctggcgca acagcatatt gaaggtcatt
     5641 atcaggtcga tccttccttg ttcaagccga atgctgattt cctgctgcgc gtcagcggga
     5701 tgtcgatgaa agatatcggc attatggatg gtgacttgct ggcagtgcat aaaactcagg
     5761 atgtacgtaa cggtcaggtc gttgtcgcac gtattgatga cgaagttacc gttaagcgcc
     5821 tgaaaaaaca gggcaataaa gtcgaactgt tgccagaaaa tagcgagttt aaaccaattg
     5881 tcgttgacct tcgtcagcag agcttcacca ttgaagggct ggcggttggg gttattcgca
     5941 acggcgactg gctgtaacat atctctgaga ccgcgatgcc gccaggcgtc gcggtttgtt
     6001 tttcatctct cttcatcagg cttgtctgca tggcattcct cacttcatct gataaagcac
     6061 tctggcatct cgccttaccc atgattttct ccaatatcac cgttccgttg ctgggactgg
     6121 tcgatacggc ggtaattggt catcttgata gcccggttta tttgggcggc gtggcggttg
     6181 gtgcaacggc gaccagcttt ctctttatgc tgttgctgtt tttacgcatg agcaccaccg
     6241 ggctgactgc gcaggcttat ggtgccaaaa atcctcaggc attagcccgt gcgctggtgc
     6301 aaccgttgct gttggcgttg ggggctgggg cgttaattgc gctgctgcgt acaccgatta
     6361 tcgatctggc tctgcatatt gttggcggta gtgaagcagt cctggaacag gcgcggcgct
     6421 ttcttgaaat ccgctggtta agcgcaccgg cgtcgctggc gaatctggta ttactcggtt
     6481 ggttactcgg cgtgcaatat gcccgtgcgc cagtaatttt gttagtggtc ggcaatatcc
     6541 tcaacattgt gctggatgtc tggctagtga tggggctgca tatgaacgtg cagggcgcgg
     6601 cgctggcgac ggttattgcg gaatatgcaa cattgctgat tggtctgcta atggtgcgta
     6661 aaatcctcaa actacgcgga atttccggcg aaatgctgaa aactgcctgg cgaggaaact
     6721 tccgtcgctt gctggcgctt aaccgcgata tcatgctgcg ttcgctgttg ttgcaactct
     6781 gtttcggcgc gatcaccgta cttggtgcgc gactggggag tgacattatc gctgttaacg
     6841 cggttctgat gacgctactc acctttaccg cctatgcgct tgatggtttt gcctacgcgg
     6901 ttgaagcgca ctccggtcag gcatacggtg cgcgcgacgg tagccagttg ctggatgtat
     6961 ggcgggcagc gtgccgccag tcggggattg tagcgttact gttttcggtg gtttatttgc
     7021 tggcagggga acacatcatt gcgttgctga cgtcgttaac ccagattcag cagctggctg
     7081 accgctatct tatctggcag gtgattttgc cgttggttgg cgtctggtgt tatctgctgg
     7141 acggcatgtt tataggcgca acgcgtgccg ccgaaatgcg taacagtatg gcggtggccg
     7201 ccgcaggttt tgcgctgacg ctccttacgc tgccgtggct gggtaatcat ggtttgtggc
     7261 tggcattaac cgtctttctg gcgttgcgcg ggctttctct ggcggctatc tggcggcgtc
     7321 actggcgtaa cggtacctgg tttgccgcaa cgtgacggtt aaaaattctg aataaattat
     7381 cctaagccaa attgctgact acacttaatc tcacgttcag aagaaaagtg aacgtactct
     7441 cattcacaac ctaacgatga ggtcttgatt atgaataaag atgaagccgg cggtaactgg
     7501 aaacagttta aaggtaaagt gaaagagcaa tggggcaaac tgaccgatga tgatatgacg
     7561 atcattgaag gtaaacgtga tcaactggtc ggtaaaatcc aggaacgtta tggttatcag
     7621 aaagatcagg cagaaaaaga ggtcgtggat tgggaaaccc gcaatgaata tcgctggtaa
     7681 ttaatccctc ctgcccgacg tgtacaagga tgtacgccct cttaacgcgg tttctttttc
     7741 acctgcacag agtgatcatg ctggcactgt tcaggatgac gacacgcttc cacttccacg
     7801 catgccgcac agagcccatg tgcttcaatc acattatgcc gcagggcaaa acccattttt
     7861 gccgccagcg tatgcatgat gtcttccacg ccttcagcac actcttcttt caccgcgccg
     7921 cagcgatcgc aaataaacat ggctgacgta tgggtgggct ggtcgaacag atgacagagc
     7981 acataactgt tggtggattc caccttatgc acaaaacctt gctcaagcag aaaatccagc
     8041 gcgcgataaa ccgttggcgg cttggcttgc ggttcagctt cgcgcagtaa atcaagcaga
     8101 tcataagcgc tgatagcgcc atcctgcaga ctcatcaggc gcaacacttc caggcgctgt
     8161 ggggtcaggc gcacattacg ctgcgcgcag attttttcag cctgcgctaa taactcctgc
     8221 gttgtggtct tttccatcgg gcacctcaaa gtgggggtta agaatgtcct tactttacca
     8281 tgttccagga aaaacaccga gaacccttat tgttgccgta atgttgattt tctgttttgt
     8341 aggtaaggtg ttgtgttgcc ttgtcgtacc attatcaaca cgataataat taataattca
     8401 tttttaaata aattgcttca agttaactcg ctatttattt aactgggttt aaacgcatac
     8461 ctgtagttca gaaattatga gcgatttttg atagtgacca gatggcaaaa gaattataag
     8521 gaggacacgg tacgacaaaa aaggtagatg aatcatgttg aagataatac ccggtgcaac
     8581 tagatacttt aataaaacac tcaat
//
LOCUS       DAPHKZ010000166         8552 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.167, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000166 DAPHKZ010000000
VERSION     DAPHKZ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8552
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.167"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            654..884
                     /locus_tag="RH288_004145"
     CDS             654..884
                     /locus_tag="RH288_004145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033138.1"
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPTPEIDPVLKAFGRHIAR
                     SFHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
     gene            936..2297
                     /locus_tag="RH288_004146"
     CDS             936..2297
                     /locus_tag="RH288_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /protein_id="HDV4033139.1"
                     /translation="MTLAAITMTAPEAASPVQMYRATYSPDDNKLRLYAVSRLDPETY
                     KKVHDAGFRWAPKQALFVAPAWTPGREDVLLSLAGEIEDEDSTLAERQEARAERFTGY
                     SGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
                     AEYWEERARSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLD
                     LNMAKLISSHDRISACFPLDTYPRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRC
                     HERQIQHQQRWVNHYQNRLIYERAMLGESGGVVTRTQDFEPGGQVFSRGEWLTIIRVN
                     KSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPG
                     EGFWEMTKAQWAALPRDCKAVRSVAEAEDHGAYRYRRTMDNNFRLVNVYITDMKITEI
                     PQK"
     gene            2344..2907
                     /locus_tag="RH288_004147"
     CDS             2344..2907
                     /locus_tag="RH288_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDV4033140.1"
                     /translation="MHSQLRERIRLMRARLDNVAPVAEIRAESQLFVTPAPVCERLVT
                     LAEISNRDHILEPSAGTGAILRAIRDTAPGAMCDAVEINSGLVRYLRENFNGVRVQCG
                     DFMEWQPVQYYSRIIMNPPFSHGQDIRHILRAFSLLRPGGVLVAVCLNGPRQQEKLLP
                     FSDVREVLPCGTFAYTRVPTMIIRLRA"
     gene            complement(2930..3266)
                     /locus_tag="RH288_004148"
                     /pseudo
     CDS             complement(2930..3266)
                     /locus_tag="RH288_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483249.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilus protein"
     gene            3747..4286
                     /locus_tag="RH288_004149"
     CDS             3747..4286
                     /locus_tag="RH288_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDV4033141.1"
                     /translation="MAVRGINKVILVGRLGKDPEVRYTPNGGAVANLQVATSESWRDK
                     QTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEIL
                     VKTTGTMQMLGRAAGAQTQPEEAQQFSGQPQPEPQAEAGTKKGGAKTKGRGRKAAQPE
                     PLPQPPEGDDYGFSDDIPF"
     gene            4349..4582
                     /locus_tag="RH288_004150"
     CDS             4349..4582
                     /locus_tag="RH288_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDV4033142.1"
                     /translation="MSEYFRILQGLPDGPFTRKHAEAVAAQYRNVFIEDDHGEQFRLV
                     VRNNGAMVWRTWNFEDGAGYWMNHAIRDFGILK"
     gene            4646..6604
                     /locus_tag="RH288_004151"
     CDS             4646..6604
                     /locus_tag="RH288_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDV4033143.1"
                     /translation="MSVTESKTKTERKSSRKPSKEQETALSALLAQTEEVSVPLSSLI
                     KSPLNVRTVPYSAESVSELADSIKGVGLLQNLVVHALPGDRHGVAAGGRRLAALNMLA
                     ERGIIPADWPVRVKVIPQELATAASMTENGHRRDMHPAEQIAGFRAMAQEGKTPAQIG
                     DLLGYSPRHVQRMLKLADLAPVILDALAEDRITTEHCQALALENDTARQVQVFEAACQ
                     SGWGGKPEVQTIRRLVTESEVVVAGNSKFRFVGADAFSPDELRTDLFSDNEGGYVDCV
                     ALDAALLEKLQAVAEHLREAEGWEWCAGRMEPVGFCREDAGTYRSLPEPEAVLTEAEE
                     ERLNELMARYDALENQCEESDLLEAEMKLIDCMAKVRAWTPEMRAGSGVVVSWRYGNV
                     CVQRGVQLRSEDDATDDADRTEQVQEKASVEEISLPLLTKMSSERTLAVQAALMQQPD
                     KSLALLAWTLCLNVFGSGAYSKPAQISLECKHYSLTSDAPSGKEGAAFMAMMAEKARL
                     AALLPEGWSRDMATFLSLSQEVLLSLLSFCTACSIHGVQTREYGHTSRSPLDSLESAI
                     GFHMRDWWQPTKANFFGHLKKPQIIAALNEAGLSGAARDAEKMKKGDAAEHAEFHMKD
                     NRWVPGWMCAPRPQTDATERTDNLADAA"
     gene            6659..7093
                     /gene="psiB"
                     /locus_tag="RH288_004152"
     CDS             6659..7093
                     /gene="psiB"
                     /locus_tag="RH288_004152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HDV4033144.1"
                     /translation="MKTELTLNVLQTMNAQEYEDIRAAGSDERRELTHAVMRELDAPD
                     NWTMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQVWVLVLVNAGGEPFAVV
                     QVQRRFAPEAVSHSLALAASLDTQGYSVNDIIHILMAEGGQV"
     gene            7090..7809
                     /locus_tag="RH288_004153"
     CDS             7090..7809
                     /locus_tag="RH288_004153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HDV4033145.1"
                     /translation="MSVRSQALVPLSTEQQAAWRAVAETEKRRHQGNTLAEYPYAGAF
                     FRCLNGSRRISLSDLRFFMPSLTAEELYGNRLQWLYVIDVLIEIQGEVCLLPLPGDAA
                     ERLFPSVRFRVRERSRHKSALVMQKYSRQQAREAEQKARAYQELVAQAEIELAFHSPE
                     TVGSWHARWSDRVAEHDLETLFWQWGERFPSLSGMERWQWQDMPFWQVIAEASLAARE
                     AGHAVREMERWMVPNKLREAA"
     gene            8084..8242
                     /locus_tag="RH288_004154"
     CDS             8084..8242
                     /locus_tag="RH288_004154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDV4033146.1"
                     /translation="MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAA
                     FMAYESGK"
BASE COUNT         1900 a         2306 c         2603 g         1743 t
ORIGIN      
        1 gttccggtcg cgccgcctct gtcgcgccgt ggcctgcgct cccggcatcc cgacatcccg
       61 acaaaaggcc gccgggatgt aaggggcaac gccgtttcgc gcacgcgctc tccgtcgttg
      121 cggcggggcc ctgctcattg cctgccgggt gccacacacc cgtatgagtc cctgtcgccg
      181 ggggctgata cagccacaac ctgccgcact gactgtccag ggtaaatgaa cagcccacaa
      241 aattttttac ccaaaacccg gtaaaaaatt ttgcgttctg cccaggacag gtgcgtcagg
      301 ccgtggcagt gatgcccctt gcggcgaagg ttctcaaacg ggtgaagttc ataccacagt
      361 gaatacagca gcaggttccc gcgaaacgtc aaaaccgcgg ctcccgaaac tcaacgggtg
      421 atgttcttta aaaatcagga tttatttcag gctccggcaa tacgcattta tttgttctgt
      481 cagtcatccg gctgacaggt aatgagaacg caggaacaga aggaggaaaa caccggaaag
      541 cgtcagatgc agatatgaaa aaagcaggtc aggcacctgc ttaatccacg ccgtaagaat
      601 tgtgcgacca attttgacgg cattgttaac caattgtcat aaggaatcca tttatgactg
      661 taagcattgt ttcaccttcc gcagcggctg taaagccccg ccgtcatccc cgtttcagac
      721 gcgaagacat ccccacgccg gaaattgacc ccgtgttgaa agccttcggg cgacacatag
      781 cccggagttt tcaccggggg cgtggtgtac acatccccgc catgaaaaac acggctttcg
      841 ggcaggtgct ccgcacactc gaactgaaac gcgcttttaa ctgatgaggt gagccgcccc
      901 gcgaggggcg gcaacagacg gaaggagaac attttatgac attagcagca atcaccatga
      961 ccgccccgga agccgccagc cctgtgcaga tgtaccgcgc gacctactca ccggatgaca
     1021 acaaactgcg cctgtatgcc gtgtcacgtc ttgacccgga gacgtataaa aaagtgcatg
     1081 atgctggttt tcgctgggca ccaaaacagg cgctgtttgt cgcgccagcc tggacaccgg
     1141 gccgggaaga cgtgctcctc tcacttgccg gagagattga ggatgaagac agcacgctcg
     1201 ctgaacgtca ggaagcacgg gcggagcggt ttaccggata cagcggaaag cgggccagtg
     1261 aatccgcaca ggcacttgat gaagtggaaa gactggccgc gatgatcccg cccggtcagc
     1321 ccattcttgt ggggcatcac agcgaacgcc gcgcccgtcg tgatgcgcag cgtattgaaa
     1381 acggcatgaa acgtgccgtg atgctctttg aacgtgcgga atactgggaa gaacgggcgc
     1441 ggtcggcact gcttcacgcg aagtataaag aacgtccgga cgttcgctgg cgtcgtatca
     1501 aaaaaatcga agctgatttg cgcaaggctg aaaagaccat cgcgcagtcg cagaaatatc
     1561 tgacgatgtg gcgggctgaa tcgctggatc tgaatatggc aaaactcatc agtagtcatg
     1621 accgtatcag tgcctgtttc ccgctggata cgtatccgcg cccggcagaa aaaagccagt
     1681 atgaaggaag tcgatcgtta tggtcggccc tggatgatga catcatcacc acggagcagg
     1741 cccgcgaaat tgcgatccgc tgtcatgaac ggcagattca gcatcagcaa cgctgggtta
     1801 accactatca gaaccgcctg atctatgagc gtgccatgct gggcgaaagc ggcggcgtgg
     1861 ttacccggac acaggatttt gagccgggcg gacaggtttt cagccggggc gagtggctga
     1921 ccatcatccg cgtgaacaaa agcaacgggg cggtgagttc agtcacaacg ccaaattaca
     1981 gttttctcgg gtacagcggc acgatgaaag tgacgcccga tcgcatcacg gactacaaag
     2041 ctccatcggc agaagaggct gccgtcgcca gtcaggccgc gaagcgtccg ccggtagtca
     2101 actatccggg ggaaggtttc tgggaaatga caaaggcgca gtgggccgcc ctgccccggg
     2161 actgtaaggc tgtgcgcagt gtggcagaag cagaagacca cggggcatac cgctaccgcc
     2221 gcacaatgga caataatttc cgcttggtga atgtgtatat caccgacatg aaaattacgg
     2281 aaatcccgca gaaataaggc ttatccccgg ggaaaagccc cggggtatga cggagataat
     2341 gacatgcaca gtcagttaag agaacgtatc cggttgatgc gcgcaaggct ggataacgtc
     2401 gcgccggttg ctgaaatccg ggctgaatct cagctttttg tgacacctgc cccggtctgt
     2461 gagcgcctgg tgacgctggc ggagatcagc aaccgagatc acattctgga accctctgcc
     2521 ggcaccgggg ccatactgcg ggctattcgg gataccgcgc cgggggccat gtgtgatgcg
     2581 gtggagatta acagcgggct ggtccggtat ctgcgggaaa attttaacgg tgtcagggta
     2641 cagtgtggcg acttcatgga atggcagccg gtgcagtatt acagccggat tatcatgaat
     2701 ccgccgttca gtcacgggca ggatatccgg catatcctgc gggccttttc cctgttgcgt
     2761 ccggggggcg tgctggtcgc cgtctgtctc aacgggccgc gccagcagga gaagctgtta
     2821 ccgttttctg atgtccgcga ggtgctgccg tgcggcacgt ttgcttatac ccgtgttccg
     2881 acgatgatta ttcgtctgcg agcctgatga cacagggcag gcgggaggat taatgcccgt
     2941 ctgcccgccc gggaaaagac cgcgcgccgg tggcgctgaa aggggccgcg ctgacgcgcc
     3001 gcccctttca ttacgcggac gttctgctgt gggcttctgt cttttcagac ctgtcatttg
     3061 tctgttactg atgatgttgt tgttcctgct acgctactgc tactgctact gctactgcta
     3121 ctgctactgt tcttcttttt tctgctgttc tgattactgc ctgttttgtt gttctcctgc
     3181 ttatgccttt tccgggcgtc cccctggcgg ggcgggctgt cgtgaacgga gccagcggag
     3241 ctgtctccgc cctggcgggc ttctatccct gacgcgaaac cctggcttgc agcgaccgtt
     3301 ccggtcgcgc cgcctctgtc gcgccgtggc ctgcgctccc ggcatcccgg caaaaggccg
     3361 ccgggatgta aggggcaacg ccgtttcgca aaccgcgctt cacgtcgctg cggcgggtcc
     3421 ctgcccgttg ttctgtccgg tgccattcac ctgtttaatt ccctgtcgcc gggggctgat
     3481 acagccacaa ccgtctccgc cagtccaggg gtgaaatgca catcccgcaa aactttttgc
     3541 ccagaagcag gcaaaaactt ttgcggtctg cccccggaca gtcgtttccg gccgtggcag
     3601 tgatgcccct tgcggcgaag gttctcaaaa aggtgatggt gaataccgga gggaacaaaa
     3661 ggcaggtccc cgcaaaacgt caaaccgcgg ctcctgaaac tcaaaagatg atgggggctg
     3721 aaaacatcaa cagaaggaga cacatcatgg cagttcgtgg cattaacaag gtcattctcg
     3781 taggacgcct gggaaaagat ccggaagtcc gttacacccc caacgggggc gcagtggcaa
     3841 acctgcaggt ggccacgtca gaaagctggc gtgacaaaca gacgggggag atgcgggagc
     3901 agacagaatg gcatcgcgtg gtgctgttcg gcaagctcgc ggaagtggca ggtgaatatc
     3961 tgcgcaaggg cgcgcaggtc tacatcgaag gtcagcttcg cacccgtagc tgggaggata
     4021 acggtatcac ccgttacgtc accgaaattc ttgttaagac cacgggcacc atgcagatgc
     4081 tgggacgtgc cgcaggtgct cagactcagc cggaagaggc gcaacagttc agcggtcagc
     4141 ctcagccgga accacaggcg gaggccggta cgaaaaaagg aggcgcaaaa acgaaaggcc
     4201 gtggacgtaa ggccgcgcag ccggagcctc tgccgcaacc gccggagggt gacgattacg
     4261 ggttttcaga cgatatcccg ttctgatcgg gctgactgtg ataaccgccc cgccccgtcc
     4321 tgtgcggggc atcaccggag aaatgaggat gagcgaatat ttcagaatac ttcaggggct
     4381 gcctgacggt ccttttaccc gcaaacatgc cgaagccgtt gccgcacagt accggaacgt
     4441 ctttatcgag gatgaccacg gcgaacagtt tcgcctggtt gtccgtaata acggtgcaat
     4501 ggtctggcgt acctggaatt ttgaggacgg tgccgggtac tggatgaacc atgccatccg
     4561 tgatttcggc attcttaagt aagagaggtg ccggacggga acgcgtccgg cagacataca
     4621 accatcccgg tcaaaggaga aatatatgtc agttacagag tctaagacaa aaacggagcg
     4681 taaatccagc cgtaaaccgt caaaagagca ggagactgcc ctgtctgccc tgctggcgca
     4741 gacggaggaa gtgagcgtgc cgctgtcctc actgattaag tcaccgctga atgtgcgcac
     4801 ggtgccgtat tctgcggagt ccgtcagcga actggcggac tccattaaag gtgtcggcct
     4861 gttacagaat ctggttgttc atgccctgcc aggtgaccgc cacggtgtcg ccgcaggtgg
     4921 tcgccgactg gcagcactca acatgctggc agagcgtggc atcattccgg ctgactggcc
     4981 tgtccgtgtg aaggtcattc cgcaggaact ggcgactgcc gcatcaatga ctgaaaacgg
     5041 tcatcgtcgg gatatgcacc ctgccgaaca gattgccgga ttccgcgcaa tggcgcagga
     5101 aggcaaaaca cctgcacaaa tcggtgattt gctgggctat tcaccccgcc acgttcagcg
     5161 aatgctgaaa ctggctgacc ttgcgcctgt catcctcgat gcgctggcag aagaccgcat
     5221 caccacagag cactgtcagg cgctggcgct ggagaacgac accgcacgtc aggtacaggt
     5281 gtttgaagct gcctgtcagt cgggatgggg cggaaaaccg gaagtacaga ccattcgtcg
     5341 tctggtgacc gaaagtgaag tggtggtggc ggggaacagt aaattccgct tcgtgggggc
     5401 tgatgccttc tcgccagatg aactgcgcac cgatttgttc agcgacaacg agggtggcta
     5461 tgtggactgc gtggcgctcg atgccgccct gctggaaaaa ctccaggctg ttgctgaaca
     5521 ccttcgggaa gccgaaggct gggaatggtg tgctggacgt atggagcctg tcggtttctg
     5581 ccgtgaggat gccggaacat accgcagtct gccggagccg gaagctgtgc tgacggaggc
     5641 ggaagaagaa cgcctgaacg aactgatggc acgttacgac gcgctggaaa atcagtgtga
     5701 ggaatccgac ctgctggaag cagaaatgaa gctgattgac tgcatggcga aggtcagggc
     5761 gtggacgccg gagatgcgtg ccggaagtgg cgtggtggtg tcctggcgtt atggaaacgt
     5821 atgtgtccag cgtggtgtgc agttgcgcag tgaagatgac gcgactgatg acgctgaccg
     5881 cacggaacag gtgcaggaga aagcatcagt ggaggaaatc agtctgccac tgctgacgaa
     5941 aatgtcttcc gaacgcacgc tggcagtcca ggcggcactc atgcagcaac cggacaaatc
     6001 tctggcactg ctggcatgga cgctctgcct gaatgtgttt ggcagcggag cgtacagtaa
     6061 accagcacaa atcagcctgg aatgtaaaca ttattcgctg accagcgatg cgccgtcagg
     6121 gaaggaaggt gccgcgttca tggcgatgat ggcagaaaaa gcccgtcttg cggccctgtt
     6181 accggaggga tggtcacggg acatggcgac gttcctgtca ctcagtcagg aggtgctgtt
     6241 gtccctgctc agtttctgca ctgcgtgcag catccacggt gttcagaccc gtgagtatgg
     6301 tcacacgtca cgcagtccgc tggattcgct ggaaagcgcc atcggctttc acatgcgcga
     6361 ctggtggcag ccgacaaaag caaacttctt cggacacctg aaaaagccgc agattatcgc
     6421 agccctgaat gaggcaggac tgtccggtgc tgcacgggac gcggagaaga tgaagaaagg
     6481 cgatgcggct gaacatgcag agttccacat gaaagacaac cgctgggtgc ctggctggat
     6541 gtgtgcacca cgcccacaga cggatgccac tgaacgcacc gataacctgg ctgatgccgc
     6601 ctgatgaaca accacaccgc cccgccggag acggggcggc agcaagggag ataccgtgat
     6661 gaaaactgaa ctgaccctga atgtattaca gaccatgaac gcacaggaat atgaagatat
     6721 ccgggctgcc ggaagtgatg aacgccgtga gctgactcac gccgtgatgc gggagctgga
     6781 tgcgccggat aactggacga tgaacggcga gtacggcagc gagtttggcg gctttttccc
     6841 cgtccaggtc cgtttcacgc ctgcccacga acgttttcac ctggcgttat gttcaccggg
     6901 cgatgtctct caggtctggg tgctggttct ggtgaatgcc ggtggtgagc cgtttgcggt
     6961 ggttcaggta cagcggcggt ttgcaccgga agccgtcagc cattcactgg cactggcggc
     7021 gtcactggat acgcaggggt acagcgttaa cgacatcatc catatcctga tggcggaagg
     7081 aggtcaggta tgagcgtacg ttcacaggca ctggttccgc tcagcacaga gcaacaggcc
     7141 gcatggcggg cggtggcgga gacagaaaaa cgccgccatc agggtaacac gctggcggaa
     7201 tatccgtatg cgggggcgtt tttccgctgt ctgaacggaa gccgcaggat atcgctgtct
     7261 gacctgcgat ttttcatgcc gtccctgacc gcagaagaac tgtacggcaa ccgtcttcag
     7321 tggctgtatg tcatcgatgt gctgattgaa atacagggcg aggtctgcct ccttcccctt
     7381 cccggtgatg cagcagagcg gttgtttccg tcggtgcggt ttcgtgtcag ggagcgcagt
     7441 cgccataaat ccgcgctggt catgcagaag tacagccgcc agcaggcacg ggaggcagag
     7501 cagaaagccc gtgcgtacca ggagctggtc gctcaggctg aaatcgaact ggcattccat
     7561 tcgccggaaa cagtcggaag ctggcatgca cgctggagtg accgggtggc agagcatgac
     7621 ctggaaaccc tgttctggca gtggggcgag cgttttccgt cactgtccgg aatggaacgc
     7681 tggcagtggc aggatatgcc gttctggcag gttattgcgg aagccagtct tgcagcaaga
     7741 gaggccggtc acgctgtccg tgagatggag cggtggatgg tgccgaacaa actccgggag
     7801 gcagcgtgat gcggcaacaa tcacacagat tacccgtaaa cagcctgaat gagcggatta
     7861 ttttcaggaa aagtgagtgt ggtcagcgtg cagggatatg ggctatgatg tgcccggcgc
     7921 ttgaggcttt ctgcctcatg acgtgaaggt ggtttgttgc cgtgttgtgt ggcagaagga
     7981 caaaagcccc gtagttaatt tttcattaac ccacgaggcc cctgcatgct tagacaacat
     8041 caggatagcc tcttaccgcg ctttgcgcaa ggagaagaag gccatgaaac taccacgcag
     8101 ctctcttgtc tggtgtgtgt tgatcgtgtg tctcacactg ttgatattca cttatctgac
     8161 acgaaaatcg ctgtgcgaga ttcgttacag agacggatac agggaggtgg cggctttcat
     8221 ggcttacgaa tccggtaagt agcaacctgg aggcgggcgc aggcccgcct tttcagggct
     8281 gatgctggtc tgactgcact gaagcgcctt tataaagggg ctgctggttc gccggtggcc
     8341 cctttctcct tgctggcatt gtacgggcat gaacaaccag actgccagga aggccgtttc
     8401 cctccgggaa cggggatgaa cgtgcgcctg cggcgcccgt tcttttcccc cgccttctct
     8461 gtttatgacc tgtcagaaat cacatcacct tccctttgat tattctcttt ttcctcctgt
     8521 tctgactctg attactgctg ccctgattat tg
//
LOCUS       DAPHKZ010000167         8517 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.168, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000167 DAPHKZ010000000
VERSION     DAPHKZ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8517
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.168"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(307..1863)
                     /locus_tag="RH288_004155"
                     /pseudo
     CDS             complement(307..1863)
                     /locus_tag="RH288_004155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066419.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(1883..2230)
                     /gene="tnpB"
                     /locus_tag="RH288_004156"
     CDS             complement(1883..2230)
                     /gene="tnpB"
                     /locus_tag="RH288_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDV4033147.1"
                     /translation="MITLPTGTRIWIIAGITDMRCGFNGLASKVQNTLKDDPFSGHIF
                     VFRGRSGKMVKILWADRDGLCLFAKRLGRGRFVWPVTREGKVHLTPAQLSMLLEGIAW
                     QHPKRTERPGIRI"
     gene            complement(2227..2901)
                     /locus_tag="RH288_004157"
     CDS             complement(2227..2901)
                     /locus_tag="RH288_004157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDV4033148.1"
                     /translation="MNSQTKKDIPCFRSYLPDALRLRFEDKLTIRAIAQRLGLSHSTI
                     PTLFQRFIASGIAWPLPDSISLAQLDAILYANRKKELTEPQISEGTWRKERRASYSRE
                     FKVRLAKQALQPGAVVARIAREHGINDNLLFKWKSQYEDGLLSDDDIQECMPVPVALT
                     DTPELTRPVTNPFWRNKPDECPECDPGNVPRCELHLKSGVVKLFDPLTPEMLRALIRE
                     MKGGTR"
     gene            complement(2984..3361)
                     /locus_tag="RH288_004158"
                     /pseudo
     CDS             complement(2984..3361)
                     /locus_tag="RH288_004158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001690050.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3606..4637)
                     /gene="f17g"
                     /locus_tag="RH288_004159"
     CDS             complement(3606..4637)
                     /gene="f17g"
                     /locus_tag="RH288_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F17G fimbrial adhesin"
                     /protein_id="HDV4033149.1"
                     /translation="MTNFYKVFLAVFILVCCNISHAAVSFIGSTENDVGPSQSSYSRT
                     HAMDNLPFVYNTGYNIGYQNANVWRISGGFCVGLDGKVDLPVVGSLDGQSIYGLTEEV
                     GLLIWMGDTNYSRGTAMSGNSWENVFSGWCVGNYVSTQGLSVHVRPVILKRNSSAQYS
                     VQKTSIGSIRMRPYNGSSAGSVQTTVNFSLNPFTLNDTVTSCRLLTPSAVNVSLAAIS
                     AGQLPSSGDEVVAGTTSLKLQCDAGVTVWATLTDATTPSNRSDILTLTGASTATGVGL
                     RIYKNTDSTPLKFGPDSPVKGNENQWQLSTGTETSPSVRLYVKYVNTGEGINPGTVNG
                     ISTFTFSYQ"
     gene            complement(4639..7107)
                     /locus_tag="RH288_004160"
     CDS             complement(4639..7107)
                     /locus_tag="RH288_004160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV4033150.1"
                     /translation="MLSVPLWAAEDAEFDPSFLSRTPGSSVIDVRRFTHGNPVPSGNY
                     YSDIYLNGEWKGNAELSFRDMSSSQEESVLCVTPELLSILDVSPEAVAREPDTGNGRC
                     MPFSAVVPDAKIRFDLSLLRLNVEIPQAMLVSRPRGYISPSQWQTGVPAAFVSYDVNH
                     WRYRTPDMENNQSYLGLRAGFNAGGWAFRHRGTESWSDGHAEGYRSIETNLQHDIAML
                     RAQLTLGDFTTTGELMDSNSLRGIRLASDDRMLPGSLRGYAPVVRGMAGSNARVTVRQ
                     NGNIIYETTVPAGPFSISDLYPSGYGGDLTVTVTESDGQTRSFIVPFASVAQLVRPGF
                     SRWQVAAGRYRYGNRTFSDTVFQGTLQYGLTNDITLNTGMSTAPHYLSGLGGVAFNTP
                     LGAVATDITLARTTFPGSDTTHRGYSLHAGYSARIPETSTNVTLAAYRYSSRDFWSLR
                     DAILTRNRDVINDSSVRSATGYRPRNQLQLTVNQSLGEGWGNLYLTGATYHYWGHTGT
                     FNEYQAGYNNVWKKMSYQIGFSQTRRSGDYHHDNRFFFSFSLPLSDTGRTLLSTTVNV
                     SDKNSNSIQSSISGVSGDDNQLSYGVSLNTQENGPTGYAVNGSYRSPVATLQATAGND
                     SRHNRQISAGISGAIVAHPFGVTASNDLGDTFTVIHADGAGGAVINNAPGNRLDPWGN
                     GIVPYVTPYEKNYISIDPTALAADVELSATEREIIPRANSTTMVTFTTKTGKAMLFDV
                     KMPDGTPPPMAAEALTADGKSAGYIAQGGRLFVRDLDAEKGMLRIVWGSGQNDSCVIH
                     YSASGENARGNAVPENHHVVCMRQ"
     gene            complement(7191..7913)
                     /locus_tag="RH288_004161"
     CDS             complement(7191..7913)
                     /locus_tag="RH288_004161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV4033151.1"
                     /translation="MKHILLFIFTVLLSLPSYGSVVIMGTRVIYPAEQKSINVRLNNG
                     DSTPSLIQAWLDTGDPSSPPDSVRVPFIITPPVFRVEPLSGQTMRIMYTGEKLPADRE
                     SLFWLNVLDIPAKPSFAGKSEKAQGYNYLQFAVRSRIKFFFRPDGLPFSPDDAYKKVT
                     WQLTGGDTLQASNPTPYFITFSTVSVGQGAQKVSSTQGGMAAPFSSVTFRLKQKVSPS
                     GKVEWTVVNDNGGYQKGESVVK"
     gene            complement(7981..8514)
                     /gene="f17a"
                     /locus_tag="RH288_004162"
     CDS             complement(7981..8514)
                     /gene="f17a"
                     /locus_tag="RH288_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F17A fimbrial adhesin"
                     /protein_id="HDV4033152.1"
                     /translation="MQFILGILAAASSSATLAYDGTITFNGKVVDQTCSVTTESKNLT
                     VTLPTVSANSLASSGKVVGLTPFTILLEGCNTPAVTGAQNVNAYFEPNANTDYTTGNL
                     TNTASSGASNVQIQLLNADGVKAIKLGQAAAAQSVDTVAINDANVTLRYNAQYYATGV
                     ATAGVVTSTVNYTIVYQ"
BASE COUNT         2081 a         2270 c         2017 g         2149 t
ORIGIN      
        1 gataaacaat tcaggtgaca tcacctgcag cagcattgct tcataagagt tcttcggcac
       61 cagaaatacc cctatattgg tatgcgcata tagctcttaa aattgcctga ggatatattt
      121 gacattaacc tgaaaaactg attacagagt caatcttaat gctggaagat tcgatctcat
      181 gctcagcaac ccatttaaca ccctttatta tcaattaatt aggcagtagc acattacatt
      241 tcctctgcta aaaggagaac atttatcttt gcaggtaagc gcaccgtgaa ggacgtgggg
      301 taaaaattag tttacagatt gagtgacatt ccagggcaac aactctttca cgcggttggc
      361 aggccaggtg ttgattacac tgatcacgtg gcgtagccac gtttccggct cgattccgtt
      421 aagtttgcag ctaccgatca ggctgtacat cactgccgca ctctcgcctc caccatcaga
      481 gccgatgaac atgtagttac gccgccccag tgcaactacc cggagggcgt tttcacacag
      541 gttattgtcg atctccaccc agccattgcg gcagtattcg ttcagagcgt cccattgctt
      601 cagcagatag gtgaacgctt tcgctgtatc cgagtggcgc gacagcgtgc tcatctgccc
      661 ctggagccac tcatacaacg actacattag cggtaccgtt ctggcttttc tgaccgccag
      721 tcgctcttct gccggactgc cgcggatctc agcctcgata gcgtacagtt caccgatacg
      781 ctgcagggct tccgtggtga tgtcagttgg cgctcttgca tgcacatcgt ggatttttct
      841 ccgggcatgg gccatacaag ccgcttcggt tacctgaccg ctttcgtaaa gagcattgta
      901 acccgcatat gcatcggcct gcaggatacc tctgtagtcc gccagatgtt gctgtgggtg
      961 gatgcctttg cggtcgggag agtatgagaa ccacaccgct gccggcatgg tcgaaccggc
     1021 gttgcgatcg tcacgaacat agacccacag ccgtccggta cgggttttac cctgacccgg
     1081 ctccagtaca tttaccggcg tgtcatcggc atgcacttta cccggcatca gcacatagtg
     1141 cttcagttca tcatacagcg ggcgaagctg ctctcccatg atgtcaaccc agcgccccat
     1201 cgtattgcgg tgcagctcca cgccctggcg ggcatagatt tccgactgac ggtacagcgg
     1261 cagatgctcg gcgaacttag ccatgattat gcgggccagc agagccggac tggcgtaact
     1321 gcgctcgatg ggttttggtg gctgcggagc ctgaactata cagtcgcacc ggctgcaggc
     1381 cagttttggg cgaaccgttt cgattaccct gaacgcggtg ttgatgatat ccagttgttc
     1441 agagatgctt tctcccagcg gtttcagttt gccgctgcag acggggcatt cggtttctgc
     1501 cggggagata acctgcctgt cacggggaag tgttgccgga agtgctttgc ggacgggaga
     1561 gtctgatgtt ttcggcgctg tctctccggc cattgaggtg agttgcaact gcgcctcacc
     1621 aagcctgttc tggagctcgg ttatacgcgt ttctgcccgt gcgatcttct tttctatctt
     1681 ctcgcggctt ttctcgctgc tgcgaccgaa caacattctc tgtagtttag cgaccagcgc
     1741 tctgagtgag ctgatctcgc gggcatagcc ggttatttca ccagacagac ggacgataac
     1801 agcctgctgt gcgatcagca gggccttcag ttgctcgatg tcgtcgggga gtgtgttgtt
     1861 cattcccctg ttttatcacg ggttatatcc ggatgccagg ccgttctgtc cgtttgggat
     1921 gttgccacgc gatcccctcc agtagcatgg ataactgagc tggcgtcagg tgcactttcc
     1981 cttcccgggt taccggccag acgaagcggc cccgtcccag gcgtttggcg aacaggcata
     2041 acccgtcacg atcggcccac agtattttca ccattttgcc acttcggccc cggaagacga
     2101 agatatgccc ggagaacggg tcatctttca gcgtgttctg caccttcgaa gccaggccgt
     2161 tgaagccaca acgcatatct gtgatgccag caatgatcca gattctggta ccggttggca
     2221 gcgttatcat cgggtacctc ctttcatttc gcggattagc gcccgtaaca tttccggagt
     2281 gagagggtca aacagtttta ccacacctga tttaagatgc agctcgcacc gtgggacgtt
     2341 tccgggatca cactcagggc actcatcagg cttgttacgc cagaagggat ttgtaactgg
     2401 tctggtcagc tctggcgtat cagtcagagc caccgggaca ggcatgcatt cctgtatgtc
     2461 atcatcgctc agtaagccgt cctcgtactg gcttttccat ttaaacagca ggttatcatt
     2521 gataccgtgc tctctggcga tccgggcaac aacagcaccg ggctgtaatg cctgcttagc
     2581 cagacggact ttaaattcac ggctgtagct ggctcgccgt tcttttcgcc atgtgccttc
     2641 gctgatttga ggctctgtta attccttctt tctgttggca taaaggatgg cgtcaagctg
     2701 agctaatgaa attgaatcgg gcaatggcca tgcgataccg gatgcaataa atcgctgaaa
     2761 aagcgtaggt attgtggaat gactgagacc tagacgctga gcgatggccc ggatggtcag
     2821 tttatcttca aatcttaaac gcagagcatc aggcaaataa gaacggaagc agggaatatc
     2881 tttttttgtc tgggaattca tcgttcgtgt ccatctatat agatgggcgc gattgttgcc
     2941 agacaggaca attttcacaa gacgtcgcag atggggcgct tacgttgatt ccgttctcac
     3001 gagctatttg tgcgacacag gcaccgggta aaagagtttg ctgaacaagt ctccatttaa
     3061 actccggtga aaatcggttc cggcgggttt tctctgtttt cacagtctga gttactgtcg
     3121 gggctgaagg gtatcgcccc gggaacagag cccgggccag ttgcacgcag gaatattccc
     3181 cggaaagagg ccagtcagtg aatacctggt gaaatcgcct caccagagaa aaaatggcgg
     3241 ttttgctgat accggtctgc gcagaaatgc gcgggtacga cagtgactcg tcaaatctca
     3301 gttgtagcac acgcaggatc aattccggat tgtctgccag taccgccttt cgtgcattca
     3361 tcttaaatgt ccctttactg cgaaaatgga cattagtatc ggaaacagga aagggaggcg
     3421 aaagacggtt taaatgagac ggttaccttc ttttttgtct ttcactgaaa aatgcctgac
     3481 aaaatcgctc atgaaaaatg ctcctgaaac gctgttatcc gcctccagaa accggtactg
     3541 ctttcaccaa cgcaaatcat tttgttatta ctgtctgacc tgttctcccc tcccggaact
     3601 cgctgttact gataggaaaa cgtaaatgtt gatattccgt taaccgtacc cggattaatt
     3661 ccctcaccag tattcacata ctttacatac aaccggactg agggtgacgt ttccgttcct
     3721 gtcgataact gccactggtt ttcatttccc tttaccggcg aatcaggtcc aaacttcagg
     3781 ggcgtactgt cagtgttttt gtatattctc agcccgactc cggttgcagt cgatgccccc
     3841 gtcagtgtga gtatatcgct tctgttggac ggtgtggtcg catcagtcag tgttgcccat
     3901 actgttactc cggcatcaca ctgtaatttc agtgatgttg tcccggcgac aacttcatca
     3961 ccggatgatg gtagttgtcc ggcagaaatt gcagccaggc tgacattgac tgcggaaggt
     4021 gtcagtaatc tgcacgatgt tactgtgtca ttcagcgtaa atggattcag gctgaaattc
     4081 actgtggtct gaacactgcc tgcagatgaa ccgttatagg gcctcattct gatactcccg
     4141 atactggttt tctgtacact gtattgcgca gaggaatttc tttttaaaat taccggtctt
     4201 acgtgaacag acagtccctg cgttgataca taatttccca cgcaccatcc ggaaaagaca
     4261 ttctcccatg agtttccact catcgcggta cccctggaat aattcgtgtc ccccatccat
     4321 ataaggagtc ccacctcctc cgtcagccca taaatactct gcccgtcaag actgccaacc
     4381 acgggtaaat ccactttccc gtccagacca acacaaaacc cgccactaat acgccagaca
     4441 tttgcattct gatatccaat gttgtaaccg gtattataga caaatggcag gttatccatt
     4501 gcatgagttc tggaataaga gctctgagac ggtccaacat cattctccgt actgccaata
     4561 aatgaaactg ccgcatggct gatattgcag caaaccagaa tgaatacagc cagaaagacc
     4621 ttataaaaat ttgtcatatt attgcctcat gcatactaca tgatggtttt ccggaacagc
     4681 atttcccctg gcattttctc cggacgcact atagtgaatg acacaactgt cattctgccc
     4741 gcttccccag actatcctga gcatcccttt ttcagcatcc aggtcacgta caaataaccg
     4801 gccaccctga gcaatgtagc ctgcagattt cccgtctgct gttaatgctt ccgcggccat
     4861 cggcggcggc gttccgtccg gcatcttcac atcaaacaac atggctttcc ccgtttttgt
     4921 tgtgaaggtc accatggtgg tactgttggc ccggggaata atttcccgct ctgttgcaga
     4981 cagttccaca tccgcagcca gcgctgtcgg gtcgatactg atataattct tttcgtaagg
     5041 tgtgacatac ggaacaatgc cgttacccca ggggtccagc cggttacccg gcgcattatt
     5101 aatcaccgcc ccaccggcac catcagcatg aataacggta aatgtgtcac caaggtcatt
     5161 actggccgtc acaccaaacg gatgcgccac tattgccccg gatataccgg cagatatctg
     5221 acggttatgg cgactgtcat tacctgccgt ggcctgcagg gtggccaccg gtgaacgata
     5281 actgccattc accgcatacc ctgtcggtcc gttttcctgg gtgttcaggg acacaccata
     5341 tgacaactga ttgtcatccc cgctgacacc actgatactg ctctgaatgc tgttactgtt
     5401 tttatcgctg acattcactg tcgtggacag caacgtcctt cccgtatctg aaagtggcag
     5461 ggaaaaactg aaaaagaacc ggttatcatg atgataatca ccactccgtc gggtctggga
     5521 aaagccaatc tggtaactca tttttttcca gacgttgtta taaccggcct ggtactcatt
     5581 gaatgtccct gtatgccccc agtaatgata agtggctccg gtcagataca ggtttcccca
     5641 tccctcacca agactctggt tcacagtcag ttgcaactga ttccttggcc ggtaaccagt
     5701 tgcactcctg accgatgaat cattaatcac atcacgattc ctggtcagga tggcatcccg
     5761 aagactccag aagtcacggg atgaataacg gtaagccgcc agcgtcacat ttgtactggt
     5821 ttccggtatt cgtgcactgt aaccggcatg caggctgtag ccgcgatgtg tcgtgtcaga
     5881 acccgggaaa gtcgttctgg ccagcgtaat atccgtggca acagccccca gtggtgtgtt
     5941 gaatgccaca ccacccagcc ctgacagata atgaggtgcg gtactcatcc ccgtattcag
     6001 ggtgatatca tttgtcagcc cgtactgcag ggtcccctgg aatacggtat cgctgaatgt
     6061 cctgttaccg taacgatacc gcccggctgc cacctgccag cgactgaacc ccgggcgaac
     6121 cagttgtgca accgaagcaa acggcacgat aaaactcctg gtctgtccgt ctgactctgt
     6181 cacagtgact gtcaggtcac caccatatcc actgggataa aggtcactga tggagaaagg
     6241 ccctgccggc acggtagttt cataaataat gttaccgttc tgccggacag tgaccctggc
     6301 gttacttccg gccatccccc gaaccacagg ggcataacca cgcaacgaac ccggcagcat
     6361 ccggtcatca gaagccagtc ttattcccct gaggctgtta ctgtccataa gctcacctgt
     6421 ggtggtgaaa tcccccagtg tcagttgcgc acgcaacatg gctatgtcgt gctgaaggtt
     6481 cgtttcaata ctccggtaac cttctgcatg accgtcactc cagctttctg tcccccggtg
     6541 acgaaatgcc cagcctcctg cgttaaagcc ggcacgaaga ccaagataac tctgattatt
     6601 ttccatatcg ggcgtccggt aacgccagtg attcacgtca taactgacaa aggcagccgg
     6661 cacccccgtc tgccactgag aaggtgatat gtatccccgt ggacgggaaa ccagcatggc
     6721 ctgcggaatt tcaacattca gccgcagcag tgacaggtca aaacggattt ttgcatcagg
     6781 tacaactgca gaaaatggca tgcaacggcc atttccggta tccggttcac gggcaacggc
     6841 ctcgggtgac acatccagaa tggataacag ttccggcgtc acacacagaa cactctcctc
     6901 ctgtgaagag gacatatcac ggaatgacaa ttccgcattt cctttccatt caccgttcag
     6961 ataaatgtct gaataataat tccctgaggg aacaggattc ccgtgcgtga aacgacggac
     7021 atcaatcaca ctgctccctg gcgtgcggct cagaaaactc gggtcaaatt ctgcatcctc
     7081 tgccgcccac aaaggcacag acagcatata cagtcccgac agacaacata aataaatgac
     7141 acggtacttc agaccggata aaaaataatg actcacttac ggggccctta ttatttcaca
     7201 acggattcgc ctttctggta accaccatta tcattcacca ccgtccattc cacttttcct
     7261 gacggagaaa ccttctgctt aagtctgaaa gtgacagaag aaaacggtgc ggccattccc
     7321 ccctgagtac tgctgacttt ctgagctccc tgcccgacac tgacagtact gaaggtaata
     7381 aaataaggcg tgggattact ggcctgaagg gtatcaccgc ctgtaagctg ccatgtcact
     7441 ttcttatatg catcatcagg agaaaaaggc agaccatcag gacggaaaaa aaacttaatc
     7501 cggctgcgta cggcaaactg aaggtaatta tatccctgtg ctttttcaga ttttcccgca
     7561 aaagaaggtt tggccggaat atcaagaaca ttcagccaga acagtgattc cctgtctgcc
     7621 ggaagttttt ctcccgtata cataattcgc attgtctgtc cggaaagcgg ctccacccgg
     7681 aaaacaggag gcgtaataat aaacggcacc ctgacagagt caggagggga agacgggtcc
     7741 cctgtatcaa gccatgcctg tatcagggat ggcgtactgt ctccgttatt cagccggaca
     7801 ttaatacttt tttgttctgc aggataaata accctggtcc ccataataac cacactgcca
     7861 tatgagggca gagacaaaag aacggtaaaa atgaacagca gaatatgttt catacaggct
     7921 ccgtaaacac ggggcaaaat gccccgtgaa cacttaagaa ggcaggtatt aagataaaaa
     7981 ttactgataa acgatggtgt aattaactgt agaagtaaca acgcctgcag tagccacacc
     8041 cgttgcgtag tactgcgcgt tataacgcaa tgtcacattt gcatcattaa tagcaactgt
     8101 atccacactc tgagctgcag cagcctgacc aagtttaata gctttaaccc catctgcatt
     8161 cagtagctga atctgaacat tagatgcacc agaagaagcc gtattagtta aattaccagt
     8221 ggtgtaatcc gtgttcgcat taggttcgaa ataagcattt acattctgag cacctgtcac
     8281 ggcaggcgta ttgcaccctt ccagcaaaat tgtgaaagga gtaagtccca ccacttttcc
     8341 gcttgaagct aatgaattag cagagacagt tggtaacgta actgtcaaat tcttgctttc
     8401 tgttgtaaca gaacaagttt gatcaacaac ttttccatta aaagtaattg taccgtcata
     8461 agcaagcgta gcagaagatg atgcagccgc cagtattcca aggataaatt gaatttt
//
LOCUS       DAPHKZ010000168         8488 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.169, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000168 DAPHKZ010000000
VERSION     DAPHKZ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8488
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.169"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..819
                     /gene="yneK"
                     /locus_tag="RH288_004163"
     CDS             <1..819
                     /gene="yneK"
                     /locus_tag="RH288_004163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
                     /protein_id="HDV4033153.1"
                     /translation="ENIEFQVVINLSPIYLDNFRHDGEINIFCAPNPKPVTMGRVFQT
                     GVERVLFLFLNDFIEQFPMINPGVPIKRAHTPHIEPLPSDHHTAADYLRQFDLLVLNF
                     ISRGNFVILPRLWNNSEVHRWFVNKDPNLITAILDITDSELKEDLLQSLMDSLGSNKH
                     VLPEVCICFLSLLAEQESPHFQNLFLFFANMLLHYHQFMNPNESDLNDVLMPASLSDD
                     KIIKHMARRTLKLFVKNETPPKVTHEDLVKNRPRSPVRPPIPATSKTPDLPERH"
     gene            969..2159
                     /gene="ydeA"
                     /locus_tag="RH288_004164"
     CDS             969..2159
                     /gene="ydeA"
                     /locus_tag="RH288_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose MFS transporter"
                     /protein_id="HDV4033154.1"
                     /translation="MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFH
                     MQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFT
                     VLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
                     GQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLT
                     VVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASAL
                     VSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLE
                     EQTQ"
     gene            complement(2184..2849)
                     /gene="marC"
                     /locus_tag="RH288_004165"
     CDS             complement(2184..2849)
                     /gene="marC"
                     /locus_tag="RH288_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter MarC"
                     /protein_id="HDV4033155.1"
                     /translation="MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     LMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSP
                     EAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
                     PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIK
                     TYH"
     gene            3061..3495
                     /gene="marR"
                     /locus_tag="RH288_004166"
     CDS             3061..3495
                     /gene="marR"
                     /locus_tag="RH288_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416047.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HDV4033156.1"
                     /translation="MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFK
                     VLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTT
                     GGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP"
     gene            3515..3898
                     /gene="marA"
                     /locus_tag="RH288_004167"
     CDS             3515..3898
                     /gene="marA"
                     /locus_tag="RH288_004167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HDV4033157.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRMTNMQGESRFLHPLNHYNS"
     gene            3930..4148
                     /gene="marB"
                     /locus_tag="RH288_004168"
     CDS             3930..4148
                     /gene="marB"
                     /locus_tag="RH288_004168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HDV4033158.1"
                     /translation="MKPLSSAIAAALILFSAQGVAEQTTQPVVTSCANVVVVPPSQEH
                     PPFDLNHMGTGSDKSDALGVPYYNQHAM"
     gene            complement(4179..5078)
                     /gene="eamA"
                     /locus_tag="RH288_004169"
     CDS             complement(4179..5078)
                     /gene="eamA"
                     /locus_tag="RH288_004169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416050.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HDV4033159.1"
                     /translation="MSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVA
                     FPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVLQAQAFFTIV
                     LGAFTFGERLHGKQLAGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAFSWACGNI
                     FNKKIMSHSTRPAVMSLVIWSALIPIIPFFVASLILDGSASMIHSLVTIDMTTILSLM
                     YLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFLGAV
                     LIMTGLYINVFGLRWRKAVKVGS"
     gene            5273..6460
                     /gene="ydeE"
                     /locus_tag="RH288_004170"
     CDS             5273..6460
                     /gene="ydeE"
                     /locus_tag="RH288_004170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HDV4033160.1"
                     /translation="MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDL
                     IGYAMTIALTIGVVFSLGFGILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLF
                     FALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI
                     NLPFWLAAICSAFPMLFIQIWVKRSEKIIATETGSVWSPKVLLQDKALLWFTCSGFLA
                     SFVSGAFASCISQYVMVIADGDFAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRAL
                     MTAGTLCFVIGLVGFIFSGNSLLLWGMSAAVFTVGEIIYAPGEYMLIDHIAPPEMKAS
                     YFSAQSLGWLGAAINPLVSGVVLTSLPPSSLFVILALVIIAAWVLMLKGIRARPWGQP
                     ALC"
     gene            6587..6682
                     /gene="mgtS"
                     /locus_tag="RH288_004171"
     CDS             6587..6682
                     /gene="mgtS"
                     /locus_tag="RH288_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HDV4033161.1"
                     /translation="MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD"
     gene            complement(6901..7791)
                     /gene="dgcZ"
                     /locus_tag="RH288_004172"
     CDS             complement(6901..7791)
                     /gene="dgcZ"
                     /locus_tag="RH288_004172"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HDV4033162.1"
                     /translation="MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEIT
                     DNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAH
                     FDAFQEGLLSFTAALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLY
                     LMLLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKAAN
                     DEEACRAGVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEG
                     KQTGRNRCMFIDEQNVINRV"
     gene            complement(8046..8438)
                     /gene="ydeI"
                     /locus_tag="RH288_004173"
     CDS             complement(8046..8438)
                     /gene="ydeI"
                     /locus_tag="RH288_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family stress tolerance OB fold protein"
                     /protein_id="HDV4033163.1"
                     /translation="MKFQAIVLASFLVMPYALADDQGGLKQDAAPPPPHAIEDGYRGT
                     DDAKKMTVDFAKTMHDGASVSLRGNLISHKGEDRYVFRDKSGEINVVIPAAVFDGREV
                     QPDQMINISGSLDKKSAPAVVRVTHLQK"
BASE COUNT         2226 a         2093 c         1882 g         2287 t
ORIGIN      
        1 gaaaatattg aatttcaggt agtaataaat ttaagcccta tttatttaga taattttcgc
       61 catgatggag aaattaatat tttttgcgct cccaacccaa agcctgtcac tatggggcgc
      121 gtatttcaga ccggcgtcga gcgtgtactc tttctgtttc tgaatgattt tattgaacaa
      181 tttccaatga tcaaccctgg tgttcccatc aaaagagcgc atacaccaca tattgaaccc
      241 ctgccttcgg atcaccatac cgctgcagat tacttacgcc agtttgattt gcttgtcctg
      301 aattttatct ctcgcggtaa ttttgtcata ctcccccgat tatggaataa ctctgaggtt
      361 cacagatggt tcgtcaataa agatcctaac ttgatcaccg ccattctcga cataacggac
      421 agcgaattaa aagaggattt gttgcaaagc ctgatggatt cattaggttc taacaaacat
      481 gtactacccg aagtctgcat ctgcttttta tcccttttag cagaacaaga atctcctcat
      541 tttcagaact tgtttttatt tttcgccaat atgttattgc actatcacca atttatgaat
      601 cccaatgaaa gtgatttgaa tgacgtgttg atgccagcat cattaagtga tgataaaatt
      661 atcaaacata tggcgcgcag gaccctcaaa ctgtttgtaa aaaatgaaac accgccaaaa
      721 gttactcacg aagacctggt gaaaaacagg cctcgctccc ctgtcagacc acctataccc
      781 gcaacctcca aaacgccaga cctccctgaa cgtcattaaa ccgtgatgtt accgactctc
      841 tgacgcgtga aagaatcagc gtcagagaaa cggaaaacgc gatccagatc acaaatgcat
      901 tgtattcaca tcattaaccg ttttaagatc atttcatcac tttttcgcaa ctcacccgat
      961 aatctgttat gacaacaaac actgtttccc gcaaagtggc gtggctacgg gtcgttacgc
     1021 tggcagtcgc cgccttcatc ttcaacacca ccgaatttgt ccctgttggc ctgctctctg
     1081 acattgcgca aagttttcac atgcaaaccg ctcaggtcgg catcatgttg accatttacg
     1141 catgggtagt agcgctaatg tcattgcctt ttatgttaat gaccagtcag gttgaacggc
     1201 gcaaattact gatctgcctg tttgtggtgt ttattgccag ccacgtactg tcgtttttgt
     1261 cgtggagctt taccgttctg gtgatcagtc gcattggtgt ggcttttgca catgcgattt
     1321 tctggtcgat tacggcgtct ctggcgatcc gtatggctcc ggccgggaag cgagcacagg
     1381 cattgagttt aattgccacc ggtacagcac tggcgatggt cttaggttta cctctcgggc
     1441 gcattgtggg ccagtatttc ggttggcgaa tgaccttctt cgcgattggt attggggcgc
     1501 ttatcaccct tttgtgcctg attaagttac ttcccttact gcccagtgag cattccggtt
     1561 cactgaaaag cctcccgcta ttgttccgcc gcccggcatt gatgagcatt tatttgttaa
     1621 ctgtggtggt tgtcaccgcc cattacacgg catacagcta tatcgagcct tttgtacaaa
     1681 acattgcggg attcagcgcc aactttgcca cggcattact gttattactc ggtggtgcgg
     1741 gcattattgg cagcgtgatt ttcggtaaac tgggtaatca gtatgcgtct gcgttggtga
     1801 gtacggcgat tgcgctgttg ctggtgtgcc tggcattgct gttacctgcg gcgaacagtg
     1861 aaatacacct cggggtgctg agtattttct gggggatcgc gatgatgatc atcgggcttg
     1921 gtatgcaggt taaagtgctg gcgctggcac cagatgctac cgacgtcgcg atggcgctat
     1981 tctccggcat atttaatatt ggaatcgggg cgggtgcgtt ggtaggtaat caggtgagtt
     2041 tgcactggtc aatgtcgatg attggttatg tgggcgcggt gcctgctttt gccgcgttaa
     2101 tttggtcaat cattatattt cgccgctggc cagtgacact cgaagaacag acgcaatagt
     2161 tgaaaggccc attcgggcct tttttaatgg tacgttttaa tgatttccag gatgccgtta
     2221 ataataaact gcacacccat acataccagc aggaatccca tcagacggga gatcgcttca
     2281 atgccaccct tgcccaccag ccgcataatt gcgccggagc tgcgtaggct tccccacaaa
     2341 ataaccgcca ccaggaaaaa gatcagcggc ggcgcaacca tcagtaccca atcagcgaag
     2401 gttgaactct gacgcactgt ggacgccgag ctaataatca tcgctatggt tcccggaccg
     2461 gcagtacttg gcattgccag cggcacaaag gcaatattgg cactgggttc atcttccagc
     2521 tcttccgact tgcttttcgc ctccggtgaa tcaatcgctt tctgttgcgg aaagagcatc
     2581 cgaaaaccga taaacgcgac gattaagccg cctgcaattc gcagaccggg aatcgaaatg
     2641 ccaaatgtat ccatcaccag ttgcccggcg taatacgcca ccatcatgat ggcaaatacg
     2701 tacaccgagg ccatcaacga ctgacgatta cgttcggcac tgttcatgtt gcctgccagg
     2761 ccaagaaata acgcgacagt tgttaatggg ttagctaacg gcagcaacac caccagcccc
     2821 aggccaattg ctttaaacaa atctaacatt ggtggttgtt atcctgtgta tctgggttat
     2881 cagcgaaaag tataaggggt aaacaaggat aaagtgtcac tctttagcta gccttgcatc
     2941 gcattgaaca aaacttgaac cgatttagca aaacgtggca tcggtcaatt cattcatttg
     3001 acttatactt gcctgggcaa tattatcccc tgcaactaat tacttgccag ggcaactaat
     3061 gtgaaaagta ccagcgatct gttcaatgaa attattccat tgggtcgctt aatccatatg
     3121 gttaatcaga agaaagatcg cctgcttaac gagtatctgt ctccgctgga tattaccgcg
     3181 gcacagttta aggtgctctg ctctatccgc tgcgcggcgt gtattactcc ggttgaactg
     3241 aaaaaggtat tgtcggtcga cctgggagca ctgacccgta tgctggatcg cctggtctgt
     3301 aaaggctggg tggaaaggtt gccgaacccg aatgacaagc gcggcgtact ggtaaaactt
     3361 accaccggcg gcgcggcaat atgtgaacaa tgccatcaat tagttggcca ggacctgcac
     3421 caagaattaa caaaaaacct gacggcggac gaagtggcaa cacttgagta tttgcttaag
     3481 aaagtcctgc cgtaaacaaa aaagaggtat gacgatgtcc agacgcaata ctgacgctat
     3541 taccattcat agcattttgg actggatcga ggacaacctg gaatcgccac tgtcactgga
     3601 gaaagtgtca gagcgttcgg gttactccaa atggcacctg caacggatgt ttaaaaaaga
     3661 aaccggtcat tcattaggcc aatacatccg cagccgtaag atgacggaaa tcgcgcaaaa
     3721 gctgaaggaa agtaacgagc cgatactcta tctggcagaa cgatatggct tcgagtcgca
     3781 acaaactctg acccgaacct tcaaaaatta ctttgatgtt ccgccgcata aataccggat
     3841 gaccaatatg cagggcgaat cgcgcttttt acatccatta aatcattaca acagctagtt
     3901 gaaaacgtga caacgtcact gaggcaatca tgaaaccact ttcatccgca atagcagctg
     3961 cgcttattct cttttccgcg cagggcgttg cggaacaaac cacgcagcca gttgttactt
     4021 cttgtgccaa tgtcgtggtt gttcccccat cgcaggaaca cccaccgttt gatttaaatc
     4081 acatgggtac tggcagtgat aagtcggatg cgctcggcgt gccctattat aatcaacacg
     4141 ctatgtagtt tgttctggcc ccgacatctc ggggcttatt aacttcccac ctttaccgct
     4201 ttacgccacc gcaagccaaa tacattgata tacagcccgg tcataatgag caccgcacct
     4261 aaaaattgca gacccgttaa gcgttcatcc aacaatagtg ccgcacttgc cagtccgact
     4321 acgggcacca gtaacgataa cggtgcaacc cgccaggttt catagcgtcc cagtaacgtc
     4381 ccccagatcc cataaccaac aattgtcgcc acaaacgcca gatacatcag cgacaagatg
     4441 gtggtcatat caatagtaac cagactgtga atcatggatg cggaaccatc gagaatcagc
     4501 gaggcaacaa agaagggaat gattgggatt aaagcgctcc agattaccag cgacatcacc
     4561 gccggacgcg ttgagtgcga catgatcttt ttattgaaga tgttgccaca cgcccaacta
     4621 aatgctgcag ccagggtcaa cataaagccg agcatcgcca catgctgacc gttcagacta
     4681 tcttcgatta acaccagtac gccaaaaatc gctaaggcga tccccgccaa ttgtttgcca
     4741 tgcagtcgct ccccgaaagt aaacgcgcca agcacgatag taaaaaacgc ctgtgcctgt
     4801 aacaccagcg aagccagtcc agcaggcata ccaaagttaa tggcgcagaa cagaaaggca
     4861 aactgcgcaa aactgatggt taatccatac cccaagagca aattcagtgg tactttcggt
     4921 cgtgcaacaa aaaagatggc cggaaaagcg accagcataa agcgcaaacc ggccagcatc
     4981 agcggtggca tgttatgaag ccccactttg atgaccacaa aatttagccc ccatacgacc
     5041 actaccagta gcgccaacac accatctttt cgcgacattc taccgcctct gaatttcatc
     5101 ttttgtaagc aatcaactta gctgaattta cttttcttta acagttgatt cgttagtcgc
     5161 cggttacgac ggcattaatg cgcaaataag tcgctatact tcggattttt gccatgctat
     5221 ttctttacat ctctaaaaca aaacataacg aaacgcactg ccggacagac aaatgaactt
     5281 atccctacga cgctctacca gcgcccttct tgcctcgtcg ttgttattaa ccatcggacg
     5341 cggcgctacg ctgccattta tgaccattta cttgagtcgc cagtacagcc tgagtgtcga
     5401 tctaatcggt tatgcgatga caattgcgct cactattggc gtcgttttta gcctcggttt
     5461 tggtatcctg gcggataagt tcgacaagaa acgctatatg ttactggcaa ttaccgcctt
     5521 cgccagcggt tttattgcca ttcctttagt gaataacgtg acgctggttg tgctcttttt
     5581 tgccctcatt aactgcgcct attctgtttt tgctaccgtg ctgaaagcct ggtttgccga
     5641 caatctttcg tccaccagca aaacgaaaat cttctcaatc aactacacca tgctaaacat
     5701 tggctggacc atcggtccgc cgctcggcac gctgttggtg atgcagagca tcaatctgcc
     5761 cttctggctg gcagctatct gttccgcgtt tcccatgctt ttcattcaaa tttgggtaaa
     5821 gcgcagcgag aaaatcatcg ccacggaaac aggcagtgtc tggtcgccga aagttttatt
     5881 acaagataaa gcactgttgt ggtttacctg ctctggtttt ctggcttctt ttgtaagcgg
     5941 cgcatttgct tcatgcattt cacaatatgt gatggtgatt gctgatgggg attttgccga
     6001 aaaggtggtc gcggttgttc ttccggtgaa tgctgccatg gtggttacgt tgcaatattc
     6061 cgtgggccgc cgacttaacc cggctaacat ccgcgcgctg atgacagcag gcaccctctg
     6121 tttcgtcatc ggtctggtcg gttttatttt ttccggcaac agcctgctat tgtggggtat
     6181 gtcagctgcg gtatttactg tcggtgaaat catttatgcg ccgggcgagt atatgttgat
     6241 tgaccatatt gcgccgccag aaatgaaagc cagctatttt tccgcccagt ctttaggctg
     6301 gcttggtgcc gcgattaacc cattagtgag tggcgtagtg ctaaccagcc tgccgccttc
     6361 ctcgctgttt gtcatcttag cgttggtgat cattgctgcg tgggtgctga tgttaaaagg
     6421 gattcgagca agaccgtggg ggcagcccgc gctttgttga tttaagtcga acacaataaa
     6481 gatttaattc agccttcgtt taggttacct ctgctaatat ctttctcatt gagatgaaaa
     6541 ttaaggtaag cgaggaaaca caccacacca taaacggagg caaataatgc tgggtaatat
     6601 gaatgttttt atggccgtac tgggaataat tttattttct ggttttctgg ccgcgtattt
     6661 cagccacaaa tgggatgact aatgaacgga gataatccct cacctaaccg gccccttgtt
     6721 acagttgtgt acaaggggcc tgatttttat gacggcgaaa aaaaaccgcc agtaaaccgg
     6781 cggtgaatgc ttgcatggat agatttgtgt tttgctttta cgctaacagg cattttcctg
     6841 cactgataac gaatcgttga cacagtagca tcagttttct caatgaatgt taaacggagc
     6901 ttaaactcgg ttaatcacat tttgttcgtc aataaacatg cagcgatttc ttccggtttg
     6961 cttaccctca tacattgccc ggtccgctct tccaatgacc acatccagag gctcttcagg
     7021 aaatgcgcga ctcacacctg ctgtcacggt aatgttgata tgcccttcag aatgtgtgat
     7081 ggcatggtta tcgactaact ggcaaattct gacacctgca cgacatgctt cttcatcatt
     7141 agccgctttg acaataatga taaattcttc gcccccgtag cgataaaccg tttcgtaatc
     7201 acgcgtccaa ctggctaagt aagttgccag ggtgcgtaat actacatcgc cgattaaatg
     7261 cccgtaggta tcattaacca atttaaatcg gtcaatatcc aacaacatta aataaagatt
     7321 cagaggctca gcgttgcgta actgatgatc aaaggattca tcaagaaccc gacgacccgg
     7381 caatcccgtc aaaacatcca tattgctacg gatcgtcagc aaataaattt tgtaatcggt
     7441 taatgccgca gtaaaagaaa gcaacccctc ctgaaaggcg tcgaaatgcg cgtcctgcca
     7501 gtgattttca acaatagcca gcattaattc ccgaccacag ttatgcatat gttgatgggc
     7561 agaatccatt agccgaacgt aaggtaattc atcgttatcg agtggcccca gatgatcaat
     7621 ccaccgacca aactggcaca gtccataaga atggttatcc gttatttctg gcttactggc
     7681 atctctcgcg accacgctgt gaaacatact caccagccac tggtagtggg catcgatagc
     7741 cttattgaga tttaacaaga tggcatcaat ttccgttgtc ttcttgatca ttgccactcc
     7801 tttttcacag ttccttgtgc gcgctattct aacgagagaa aagcaaaatt acgtcaatat
     7861 tttcatagaa atccgaagtt atgagtcatc tctgagataa cattgtgatt taaaacaaaa
     7921 tcagcggata aaaaagtgtt taattctgta aattacctct gcattatcgt aaataaaagg
     7981 atgacaaata gcataaccca ataccctaat ggcccagtag ttcaggccat caggctaatt
     8041 tatttttatt tctgcaaatg agtgacccga acgacggccg gcgcgctttt cttatccaga
     8101 ctgccactaa tgttgatcat ctggtccggc tgaacttctc gtccatcaaa gacggccgca
     8161 ggaataacga cattaatttc accgctctta tcgcgaaaaa cgtaacggtc ctctcctttg
     8221 tgagaaatca aattaccgcg tagtgaaacc gaagcgccat cgtgcatggt ttttgcgaaa
     8281 tcaacggtca ttttttttgc atcatcggtt ccgcgatagc catcttctat tgcatgaggc
     8341 ggcggtggcg ctgcatcctg ttttaaaccg ccctggtcat ctgccaacgc ataaggcatg
     8401 acaagaaaac ttgctaatac aatggcctga aatttcatac taactcctta attgcgtttg
     8461 gtttgactta ttaagtctgg ttgctatt
//
LOCUS       DAPHKZ010000169         8479 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.170, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000169 DAPHKZ010000000
VERSION     DAPHKZ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8479
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.170"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            84..974
                     /gene="alsR"
                     /locus_tag="RH288_004174"
                     /gene_synonym="rpiR"
     CDS             84..974
                     /gene="alsR"
                     /locus_tag="RH288_004174"
                     /gene_synonym="rpiR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418513.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="als operon DNA-binding transcriptional repressor
                     AlsR"
                     /protein_id="HDV4033164.1"
                     /translation="MSQSEFDSALPNGIGLAPYLRMKQEGMTENESRIVEWLLKPGNL
                     SCAPAIKDVAEALAVSEAMIVKVSKLLGFSGFRNLRSALEDYFSQSEQVLPSELAFDE
                     APQDVVNKVFNITLRTIMEGQSIVNVDEIHRAARFFYQARQRDLYGAGGSNAICADVQ
                     HKFLRIGVRCQAYPDAHIMMMSASLLQEGDVVLVVTHSGRTSDVKAAVELAKKNGAKI
                     ICITHSYHSPIAKLADYIICSPAPETPLLGRNASARILQLTLLDAFFVSVAQLNIEQA
                     NINMQKTGAIVDFFSPGALK"
     gene            1033..1968
                     /gene="alsB"
                     /locus_tag="RH288_004175"
     CDS             1033..1968
                     /gene="alsB"
                     /locus_tag="RH288_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose transporter substrate-binding protein"
                     /protein_id="HDV4033165.1"
                     /translation="MNKYLKYFSGTLVGLMLSTSAFAAAEYAVVLKTLSNPFWVDMKK
                     GIEDEAKTLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIAFAPLSSVNLVMPVAR
                     AWKKGIYLVNLDEKIDMDNLKKAGGNVEAFVTTDNVAVGAKGASFIIDKLGAEGGEVA
                     IIEGKAGNASGEARRNGATEAFKKASQIKLVASQPADWDRIKALDVATNVLQRNPNIK
                     AIYCANDTMAMGVAQAVANAGKTGKVLVVGTDGIPEARKMVEAGQMTATVAQNPADIG
                     ATGLKLMVDAEKSGKVIPLDKAPEFKLVDSILVTQ"
     gene            2095..3627
                     /gene="alsA"
                     /locus_tag="RH288_004176"
     CDS             2095..3627
                     /gene="alsA"
                     /locus_tag="RH288_004176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter ATP-binding protein
                     AlsA"
                     /protein_id="HDV4033166.1"
                     /translation="MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGK
                     STLMKVLSGIHEPTKGTITINNISYNKLDHKLAAQLGIGIIYQELSVIDELTVLENLY
                     IGRHLTKKICGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL
                     MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVM
                     KDGSSVCSGIVSDVSNDDIVRLMVGRELQNRFNAMKENVSNLAHETVFEVRNVTSRDR
                     KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLD
                     AVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQ
                     RELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYK
                     VMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEEEIMAWALP
                     QE"
     gene            3606..4586
                     /gene="alsC"
                     /locus_tag="RH288_004177"
     CDS             3606..4586
                     /gene="alsC"
                     /locus_tag="RH288_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter permease"
                     /protein_id="HDV4033167.1"
                     /translation="MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSP
                     EYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGV
                     DPFLAAMIGGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYG
                     FSFDFVNFFAASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGI
                     DVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGK
                     GRIFSVVISGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALDRLISK"
     gene            4597..5292
                     /gene="alsE"
                     /locus_tag="RH288_004178"
     CDS             4597..5292
                     /gene="alsE"
                     /locus_tag="RH288_004178"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allulose-6-phosphate 3-epimerase"
                     /protein_id="HDV4033168.1"
                     /translation="MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTL
                     SPFFVSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEI
                     RRHDMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAW
                     REREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQIL
                     AAKSEVQPHAKTA"
     gene            5276..6205
                     /gene="alsK"
                     /locus_tag="RH288_004179"
     CDS             5276..6205
                     /gene="alsK"
                     /locus_tag="RH288_004179"
                     /EC_number="2.7.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allose kinase"
                     /protein_id="HDV4033169.1"
                     /translation="MQKQHNVVAGVDMGATHIRFCLRTAEGETLHCEKKRTAEVIAPG
                     LVSGIGEMIDEQLRRFNARCHGLVMGFPALVSKDKRTIISTPNLPLTAADLYDLADKL
                     ENTLNCPVEFSRDVNLQLSWDVVENRLTQQLVLAAYLGTGMGFAVWMNGAPWTGAHGV
                     AGELGHIPLGDMTQHCACGNPGCLETNCSGMALRRWYEQQPRNYPLRDLFVHAENAPF
                     VQSLLENAARAIATSINLFDPDAVILGGGVMDMPAFPRETLVAMTQKYLRRPLPHQVV
                     RFIAASSSDFNGAQGAAILAHQRFLPQFCAKAP"
     gene            6478..8463
                     /gene="yjcS"
                     /locus_tag="RH288_004180"
     CDS             6478..8463
                     /gene="yjcS"
                     /locus_tag="RH288_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl sulfatase YjcS"
                     /protein_id="HDV4033170.1"
                     /translation="MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVN
                     QNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKVYYRADDYKFDINAAAPETV
                     NPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
                     LDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISE
                     NVLAGNIMSRRALYSYGLLLPHNAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMI
                     IDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFYTLRGAKTRDTSKWT
                     EYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTIKYIHDQTLHLANQGYT
                     MNEIGDMIKLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMG
                     KRYVQALGGSARVINLAQEANKQGDYRWSAELLKQVIAANPGDQVAKNLQANNFEQLG
                     YQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMSVRLDSAKA
                     AGKNISLNFNMGNGDNLNLTLNDSVLNYRKTLQPQANASFYISREDLHAVLTGQAKMA
                     DLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTPN"
BASE COUNT         2192 a         2065 c         2169 g         2053 t
ORIGIN      
        1 tttttttgtg aagtcgccag catcttttct gttcttgctg tggtgatata gtggcgtctt
       61 caattcaagg acaagagaac gtgatgagcc agtcagagtt tgattcagcg cttccgaacg
      121 gtatagggtt agcgccttac ctgcgaatga agcaggaagg aatgacagaa aatgaaagcc
      181 gcatcgtgga gtggttactc aaacccggta acctgagttg tgcacccgca attaaagatg
      241 tcgcagaagc tctggcggta tctgaagcga tgatagttaa ggtatcaaag ctgctggggt
      301 ttagcggctt tcgtaactta cgcagtgcgc tggaagatta tttttctcag tcagaacagg
      361 tattgccttc cgagttggct tttgatgaag cgccgcagga tgtggtgaat aaggtattta
      421 acatcacttt acgcaccatt atggaaggtc agtcgatcgt caacgttgat gagatccacc
      481 gtgccgcccg ctttttctat caggccagac agcgggattt gtacggtgcc ggaggatcaa
      541 atgctatctg tgctgatgta cagcacaagt tcttgcgcat tggcgtacgc tgtcaggcct
      601 atcctgatgc tcacatcatg atgatgtccg cttcgttgtt acaggaagga gatgttgtgc
      661 tggtagtgac ccattccggg cgaaccagtg atgtaaaagc ggccgtagaa ctggcaaaaa
      721 agaacggggc aaagattatt tgtataaccc atagctacca ttcaccgata gcgaaactgg
      781 ccgattatat tatttgctca ccagccccgg aaacgccgtt attaggtcgt aatgcctcgg
      841 caagaatatt acaactaact ttgctggacg ctttttttgt ctctgtcgcc cagctcaaca
      901 ttgaacaagc taatattaat atgcaaaaaa ccggcgcaat tgttgatttc ttctcaccag
      961 gcgcgctgaa ataagaaaaa ggtaattccg ccatcgcgga gttacctgtc cccttaccgt
     1021 gagaacatta ttatgaataa atatctgaaa tatttcagcg gcacactcgt gggcttaatg
     1081 ttgtcaacca gcgcttttgc tgccgccgaa tatgctgtcg tattgaaaac cctctccaac
     1141 ccattttggg tagatatgaa aaaaggcatt gaagatgaag caaaaacact gggcgtcagc
     1201 gttgatattt ttgcctctcc ttcagaaggc gattttcaat ctcaattgca gttatttgaa
     1261 gatctcagta ataaaaatta caaaggtatc gccttcgctc cattatcctc agtgaatctg
     1321 gtcatgcctg tcgcccgcgc atggaaaaaa ggcatttatc tggttaatct cgatgaaaaa
     1381 atcgacatgg ataatctgaa aaaagctggc ggcaatgtgg aagcttttgt caccaccgat
     1441 aacgttgctg tcggggcgaa aggcgcgtcg ttcattattg acaaattggg cgctgaaggt
     1501 ggtgaagtcg caatcattga gggtaaagcc ggtaacgcct ccggtgaagc gcgtcgtaat
     1561 ggtgccaccg aagccttcaa aaaagcaagc cagatcaagc ttgtcgccag ccagcctgcc
     1621 gactgggacc gcattaaagc actggatgtc gccactaacg tgttgcaacg taatccgaat
     1681 attaaagcga tctattgcgc gaatgacacg atggcaatgg gtgttgctca ggcagtcgca
     1741 aacgccggaa aaacgggaaa agtgctggtc gtcggtacag atggcattcc ggaagcccgc
     1801 aaaatggtgg aagccggaca aatgaccgcg acggttgccc agaacccggc ggatatcggc
     1861 gcaacgggtc tgaagctgat ggttgacgct gagaaatccg gcaaggttat cccgctggat
     1921 aaagcaccgg aatttaaact ggtcgattca atcctggtca ctcaataaaa ctgaatgatg
     1981 ccggatgatg atgctaatga agtgtcttat ccggccaaca aaataacctg aacgtagacc
     2041 tgataaatgt agccatcagg caataatacg atatttcgtg cagagaggtt atttatggcc
     2101 acgccatata tatcgatggc ggggatcggc aagtcctttg gtccggttca cgcattaaag
     2161 tcggttaatt taacggttta tcctggtgaa atacatgcat tactaggaga aaatggcgcg
     2221 ggtaaatcca cgctaatgaa agttttatcc ggaatacatg agccgaccaa aggcaccatt
     2281 accattaata acattagcta taacaagctg gatcataaat tagcggcaca actcggtatc
     2341 gggattattt atcaggaact cagcgttatt gatgaattaa ccgtactgga aaatttatat
     2401 attggtcgtc atctgacgaa aaaaatctgt ggcgtcaata ttatcgactg gcgagaaatg
     2461 cgtgtccgcg ccgccatgat gttattacgc gtgggcttga aagttgatct agatgagaaa
     2521 gtggcgaatt tatctatcag ccacaagcag atgctagaaa ttgccaaaac gctgatgctc
     2581 gatgccaaag tcatcatcat ggatgaaccc acctcctcac tcaccaataa agaggtggac
     2641 tatctgtttc tgatcatgaa tcagttgcgt aaagagggta cggccatcgt ctatatctcg
     2701 cataagttgg cggaaattcg ccgtatttgc gaccgctata cggtgatgaa agacggcagc
     2761 agcgtttgca gcggcatagt aagcgatgtg tcaaatgacg atatcgtccg tctgatggta
     2821 ggccgcgaac tgcaaaaccg ttttaacgcg atgaaggaga atgtcagcaa ccttgcgcac
     2881 gaaacggttt ttgaggtgcg gaacgtcacc agtcgtgaca gaaaaaaggt ccgggatatc
     2941 tcatttagcg tctgccgggg agaaatatta ggctttgccg gactggtcgg ttccggacgt
     3001 actgaactga tgaattgtct gtttggcgtg gataaacgcg ctggcggaga aatccgtctt
     3061 aatggcaaag atatctctcc acgttcaccc ctggatgccg tgaaaaaagg gatggcttac
     3121 atcactgaaa gccgccggga taacggtttt ttccccaact tttccatcgc tcagaacatg
     3181 gcgatcagcc gcagtctgaa agacggcggc tataaaggcg cgatgggctt gtttcatgaa
     3241 gttgacgagc aacgtaccgc tgaaaatcaa cgcgaactgc tggcgctgaa atgtcattcg
     3301 gtaaaccaga atatcaccga actctccggg ggaaatcagc agaaagtcct gatctccaaa
     3361 tggctgtgct gttgcccgga agtgattatt ttcgatgaac ctacccgcgg catcgacgtt
     3421 ggcgcgaaag ccgaaattta caaagtgatg cgccaactgg cggacgacgg aaaagtcatc
     3481 ctgatggtgt catctgaact acctgaaatt atcaccgtct gcgaccgcat cgccgtgttc
     3541 tgcgaaggac gactgacgca aatcctgacg aatcgcgatg acatgagcga agaggagatt
     3601 atggcatggg ctttaccaca agagtaaaaa gcgaagcgag cgagaagaaa ccgttcaact
     3661 ttgcgctgtt ctgggataaa tacggcacct tttttatcct ggcgatcatc gtcgccatct
     3721 ttggttcgct gtcaccagaa tattttctga ccaccaataa tattacccag atttttgttc
     3781 aaagctccgt gacggtattg atcggcatgg gcgagttttt cgctatcctg gtcgctggta
     3841 tcgacctctc ggttggcgcg attctggcgc tttccggtat ggtgaccgcc aaactgatgt
     3901 tggcaggtgt tgacccgttt ctcgcagcga tgattggcgg tgtactggtt ggcggcgcac
     3961 tgggggcgat caacggctgc ctggtcaact ggacggggct acacccgttc atcatcaccc
     4021 ttggcaccaa cgcgattttc cgtgggatca cgctggtgat ctccgatgcc aactcggtat
     4081 acggcttctc atttgacttc gtgaacttct ttgccgccag cgtaattggg atacctgtcc
     4141 ccgttatctt ctcactaatt gtcgcgctca tcctttggtt tctgacaacg cgtatgcggc
     4201 tcgggcgcaa catctacgca ctgggcggca acaaaaattc ggcgttctat tccgggattg
     4261 acgtgaaatt ccacatcctg gtggtgttta tcatctccgg tgtttgtgca ggtctggcag
     4321 gcgtcgtctc aactgcacga ctcggtgccg cagaaccgct tgccggtatg ggttttgaaa
     4381 cctatgccat tgccagcgcc atcattggcg gcaccagttt cttcggcggc aaggggcgca
     4441 ttttctctgt ggtgattagc gggttgatca tcggcaccat caacaacggt ctgaatattt
     4501 tgcaggtaca aacctattac caactggtgg tgatgggcgg attaattatc gcggctgtcg
     4561 cccttgaccg tcttatcagt aagtaaggaa ttgaacatga aaatctcccc ctcgttaatg
     4621 tgtatggatc tgctgaaatt taaagaacag atcgaattta tcgacagcca tgccgattac
     4681 ttccacatcg atatcatgga cggtcacttt gtccccaatc tgacactctc accgttcttc
     4741 gtaagtcagg ttaaaaaact ggcaactaaa ccgctcgact gtcatctgat ggtgacgcgg
     4801 ccgcaggatt acattgctca actggcgcgt gcgggagcag atttcatcac tctgcatccg
     4861 gaaaccatca acggccaggc gttccgcctg attgatgaaa tccgccgtca tgacatgaaa
     4921 gtggggctga tccttaaccc ggagacgcca gttgaggcca tgaaatacta tatccataag
     4981 gccgataaaa ttacggtcat gactgtcgat cccggctttg ccggacaacc gttcattcct
     5041 gaaatgctgg ataaacttgc cgaactgaag gcatggcgtg aacgagaagg tctggagtac
     5101 gaaattgagg tggacggttc ctgcaaccag gcaacttacg aaaaactgat ggcggcaggg
     5161 gcggatgtct ttatcgtcgg cacttccggc ctgtttaatc atgcggaaaa tatcgacgaa
     5221 gcatggagaa ttatgaccgc gcagattctg gctgcaaaaa gcgaggtaca gcctcatgca
     5281 aaaacagcat aacgtcgtag cgggcgtgga tatgggggca acgcatatcc gcttttgtct
     5341 gcggacagca gaaggtgaaa cgctacactg cgaaaaaaag cggaccgcag aagtcattgc
     5401 tcccggcctg gtgtcgggta tcggcgaaat gattgacgag caactcaggc gctttaacgc
     5461 tcgctgtcat ggtctggtga tgggatttcc ggcgctggtc agtaaagata aacgcaccat
     5521 tatttctacg cctaacctgc cgttaacagc ggcggattta tatgatctcg ccgataagct
     5581 cgaaaatacg ctgaattgtc cggttgagtt ttcccgcgac gttaacctgc aactctcctg
     5641 ggacgtagta gaaaaccgcc ttacgcaaca actggttctg gcggcctatc tcggtacggg
     5701 gatggggttc gcagtgtgga tgaacggtgc gccgtggacg ggtgcacacg gtgtggcagg
     5761 cgaactgggt catatccccc tgggagatat gacccaacac tgcgcgtgtg gcaatcctgg
     5821 gtgcctggaa accaattgct ctggaatggc gctaagacgc tggtacgaac aacagccccg
     5881 aaattaccca ttgcgcgatc ttttcgtcca tgcggaaaac gcccctttcg tccagagtct
     5941 gcttgaaaac gcggcacggg ccattgccac cagcattaat ctgttcgatc ccgatgcggt
     6001 gatcctgggc ggtggcgtga tggatatgcc cgccttccca cgcgagactc tcgttgccat
     6061 gacccaaaag tacctgcgcc gtccactgcc gcatcaggtc gtgcgcttta ttgccgcctc
     6121 atcttctgac tttaatggcg ctcagggtgc agcaatattg gcgcatcaac gttttttgcc
     6181 acagttctgt gctaaagccc catgagtaaa acgttggcac agtagcgcaa tgtcccgctg
     6241 tgccaacgac aggtacaata tatataataa acacataaaa cgactcatat tattttctgc
     6301 aatgatagtt ttactgtaat tttccctctt cagcacaaat gcctaataaa atggcgcgtt
     6361 ccgctcacac ttccacttat taaagtcgca atttcccaat tatgataacg ccagctttaa
     6421 atgacgtatt ttgcatggat tacatattta cgacataaat gataaatgga gatttatatg
     6481 aataactctc ggttattccg tttgagcagg attgttattg cgttaactgc cgccagcggc
     6541 atgatggtaa ataccgctaa cgcgaaagag gaagcgaaag ccgccactca atatacccaa
     6601 caggttaatc agaattacgc caaatcatta ccgtttagcg atcgtcagga ttttgacgat
     6661 gcccagcgtg gatttatcgc cccgctgctg gatgaaggta ttctgcgtga tgcgaacggt
     6721 aaagtttact accgcgcgga cgattacaaa tttgatatta atgccgcagc gccggaaacc
     6781 gtaaacccca gcctgtggcg tcagtcgcaa atcaacggta tttctggcct gttcaaagtc
     6841 accgataaaa tgtatcaggt gcgcggccag gatatctcta acattacgtt cgttgagggc
     6901 gagaaaggca ttattgttat cgacccgctg gtgacgccgc ctgccgcaaa agccgcactt
     6961 gacctttact tccagcatcg tccgcaaaaa ccgattgttg ccgttatcta cactcacagc
     7021 cacaccgacc actatggtgg cgtgaaaggc attatctctg aagccgatgt taaatccggc
     7081 aaagttcagg tgattgcccc tgcaggcttt atggacgaag ccatcagcga aaacgtgctg
     7141 gcgggtaaca tcatgagccg ccgtgcgctc tactcttacg gtctgttact gccgcacaac
     7201 gcgcaaggca acgtgggtaa tggccttggc gtgacgctgg caacgggcga cccgagcatt
     7261 attgcaccga ctaaaactat cgtccgaact ggcgagaaga tgattatcga cggcctggag
     7321 tttgacttcc tgatgacccc aggtagcgaa gcgccagccg aaatgcactt ctatattccg
     7381 gccctgaaag ccctgtgtac cgccgagaac gccacgcata ccctgcacaa cttctacact
     7441 ctacgcggcg cgaaaacccg cgacaccagc aagtggaccg agtatctgaa cgaaacgctg
     7501 gatatgtggg gtaacgacgc ggaagtcctg tttatgccgc acacctggcc ggtctggggc
     7561 aataagcata tcaatgatta tattggtaaa tatcgcgata ctatcaagta cattcacgac
     7621 cagaccctgc acctggcgaa ccagggctac accatgaatg aaatcggcga catgattaag
     7681 ctgccgcctg cacttgccaa taactgggcc agccgtggct attacggttc tgtcagccac
     7741 aacgcccgcg cggtgtataa cttctatctt ggctattacg acggtaaccc ggctaacctg
     7801 catccgtatg gtcaggtgga gatgggtaaa cgttacgtgc aggcgctggg cggttctgcc
     7861 cgtgtcatca acctggcgca agaagcgaac aagcaaggtg attaccgctg gtcggcagaa
     7921 ctgctgaaac aggtgattgc cgccaacccg ggtgaccagg tcgcgaagaa tctgcaagcg
     7981 aataactttg aacagctggg ctatcaggcc gagtccgcca cctggcgcgg tttctacctg
     8041 accggcgcga aagagctgcg cgaaggggtg cataagttca gccacggcac caccggttcc
     8101 ccggacacca ttcgcgggat gtcggtcgaa atgctgttcg actttatgtc cgttcgcctc
     8161 gatagcgcga aagccgcggg taaaaatatc agcctgaact tcaatatggg caacggcgat
     8221 aacctcaacc tgacgctgaa cgatagtgtg cttaactacc ggaaaacgct gcaaccgcaa
     8281 gccaacgcct ctttctacat cagccgtgaa gatctgcacg ccgtgctgac cggacaggca
     8341 aaaatggcgg atctggtaaa agcgaagaaa gccaaaatta ttggcaatgg cgcgaaactg
     8401 gaagaaatta ttgcctgtct ggataatttc gatttgtggg tgaatatcgt aaccccaaat
     8461 taatgccact cgcttttgg
//
LOCUS       DAPHKZ010000170         8426 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.171, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000170 DAPHKZ010000000
VERSION     DAPHKZ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8426
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.171"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(600..1793)
                     /gene="tyrB"
                     /locus_tag="RH288_004181"
     CDS             complement(600..1793)
                     /gene="tyrB"
                     /locus_tag="RH288_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HDV4033171.1"
                     /translation="MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIP
                     QLQAVAEAEARLNAQPHGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTL
                     GGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
                     NDLLATLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGF
                     GAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQL
                     KATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRILAMRQELVKVLSTEM
                     PERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGVYLIASGRMCVAGLNTANVQRVAKA
                     FAAVM"
     gene            complement(2046..3125)
                     /gene="alr"
                     /locus_tag="RH288_004182"
     CDS             complement(2046..3125)
                     /gene="alr"
                     /locus_tag="RH288_004182"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDV4033172.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNE
                     EQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
                     ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVS
                     PLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYVD"
     gene            complement(3178..4593)
                     /gene="dnaB"
                     /locus_tag="RH288_004183"
     CDS             complement(3178..4593)
                     /gene="dnaB"
                     /locus_tag="RH288_004183"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDV4033173.1"
                     /translation="MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
                     AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKT
                     AGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASL
                     SRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREH
                     GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            4676..5659
                     /locus_tag="RH288_004184"
     CDS             4676..5659
                     /locus_tag="RH288_004184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HDV4033174.1"
                     /translation="MATRIEFHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFID
                     TYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYAQSALGAYSSVHNII
                     ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREENLVERLKEITGGKKVRVVYDSVG
                     RDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILESRATQGSSLLIP"
     gene            complement(5825..6067)
                     /gene="pspG"
                     /locus_tag="RH288_004185"
     CDS             complement(5825..6067)
                     /gene="pspG"
                     /locus_tag="RH288_004185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HDV4033175.1"
                     /translation="MLELLFVIGFFVMLMVTGVSLLGIIAALVVATAIMFLGGMLALM
                     IKLLPWLLLAIAVVWVIKAIKAPKVPKYQRYDRWRY"
     gene            complement(6201..7238)
                     /gene="dusA"
                     /locus_tag="RH288_004186"
     CDS             complement(6201..7238)
                     /gene="dusA"
                     /locus_tag="RH288_004186"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HDV4033176.1"
                     /translation="MHGNSEMQKINQTSAMPEKTDVHWSGRFSVAPMLDWTDRHCRYF
                     LRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEA
                     RGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDD
                     QDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDF
                     PHLTMSINGGIKSLEEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDIDADPV
                     AVVRAMYPYIERELSQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVL
                     EHALKLVADKR"
     gene            complement(7601..8426)
                     /locus_tag="RH288_004187"
                     /pseudo
     CDS             complement(7601..8426)
                     /locus_tag="RH288_004187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560258.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2713 domain-containing protein"
BASE COUNT         2247 a         2128 c         1957 g         2094 t
ORIGIN      
        1 tagaaacaca gttaaaaatt gcaaaagatt ttttagacct ggagaagaag tatcaagttc
       61 tattgcaagt aaagtttttc acgcatttat tgatttagtt aacaaaatca ggggtaagaa
      121 agactttatg tatatttgca cgctttgctg ttttgccgag gaggttaaag gtgattattc
      181 tcattacagg acctttttat ttgatattgg taatcaatat aaggttaaac ttacacaaag
      241 cggaaaaaag agttctcttt aacattagaa tttaacgata ctataattga atctcagaaa
      301 gtcacaggca ataaggcaaa gcatattctt gaggatatag aaatattcta tcgtaacaaa
      361 cccgatactt attattaaat ttaataatgg ttagatgtgc agaaattatt actccaccca
      421 aaaaaacagg ataaggaatt ccagataatt gggataagct taacaataaa agaactaaca
      481 acgtttatta tctctcacgt agaacgatgg catcaaaaaa atcatctata aagaaagagt
      541 gaaagcgacg acagtttaat ttcactgcag gctgggtagc tccagcctgc tttcctgcat
      601 tacatcaccg cagcaaacgc ctttgccaca cgttgtacat ttgccgtatt taacccggcg
      661 acacacatgc gaccgctggc gatgagatag acaccaaatt cttcacgtag tcggtcaacc
      721 tgagcggcac ttaaaccggt ataactgaac atgccgcgct gattaagcag ataatcgaaa
      781 ttgcgttctg gcatctctgt gcttaatacc ttcaccaatt cctgacgcat tgccagaatg
      841 cgagtacgca tctcttctac ttccgccagc cagctggctt tcaatgcctc gtcattcagc
      901 actgcagcca ccacctgcgc accaaaattc ggcgggctgg agtagttgcg gcgaactgtt
      961 gctttcaatt gccccagtac gcggccagcg gcttcggcat cttcacacat aacagaaagt
     1021 ccgccgacgc gctcgccgta aagggagaaa attttcgaga acgaattgct caccagagcg
     1081 ggtaatccag cgctggcaat ggcgcgaata gcgtaggcat cctcttccat accggcacca
     1141 aatccttgat aggcaatatc gaggaatgga ataagctcgc gggctttgag aatttcaatc
     1201 accgcatccc actgatcatt agtgagatcg gcacccgttg ggttgtggca acatggatgc
     1261 agcaacacaa tactgcgggc aggtaatgtt ttcagcgtcg ccaacaggtc attaaagcgc
     1321 acgccgttag tcgcttcgtc ataccagggg taagtactca cttcgaatcc agccccggcg
     1381 aatattgcta cgtggttttc ccaggtagga tcgctgaccc agacgcctga ttccgggaag
     1441 tagcgtttca ggaaatccgc gcccactttc aatgccccgg agccgccaag ggtttgaatg
     1501 gttgctacgc gctgttgttt cagtaccgga tggtccgcac caaacagcag cggcgcaatg
     1561 gcatggcgat agcagttaag cccttccatc ggtaaataaa gcgaagcgcc atgaggctgc
     1621 gcattcaggc gcgcttccgc ctccgccacg gcttgcagtt gtggaataat tccgtcttcg
     1681 ttgtagtaca gaccgatact taaattcact ttgtcgctgc gagggtcttc tttaaaacgc
     1741 tccataagcg taagaatcgg gtcgccagcg taggcgtcaa ctttttgaaa cacgcgatgg
     1801 ttctccaggt ttacgggcag gtggttaaaa cacaataaac cggaagaagg cgaagatcga
     1861 gtggatgttc aggagcgaac ggcaattagc aacagagtga gactcatgac aaacgtacat
     1921 ccgccagagg cacgaccttt ataagaacat gaaagaacat caacttattg aatttttagg
     1981 attttattgg ccggataagg cattcacgcc gcatccggca cagacaatca aatattacag
     2041 aacgattaat ccacgtattt catcgcgacc cttgaagtca ggcgcgtaat aagttcgtaa
     2101 gcgcttactt tcgtcatttc agcgatacgt tctacgggca aaccttcgcc ccataaaatg
     2161 accggatccc cggctttgtc ctgcgcctgt ggacctaagt ctacgcagat catatccatc
     2221 gccacgcgcc cgacaatcgg tacttcgcga ccgttcacca gcactggcgt accggacggc
     2281 gcggcgcgcg gataaccatc gccatagccc atcgcgacta cgccaagacg ggtatcacgt
     2341 tcgcttaccc aggttccacc ataaccaaca ggctctccgg ctttatgctc acgcacggca
     2401 atcaggctgg aggttagtga catcactggc tgacagccaa aatcggcacc ggtggagcga
     2461 tcttccagcg gcgagacgcc ataaagaatg atgcccgggc gcacccagtc aaaatgcgac
     2521 tgtggccaca gcagaatgcc acccgacgcg gcaatggaac gttgaccagg tttgccttcg
     2581 caaaaggtat taaagatagc gagttgtttc tcggttgcgc cacattttgg ttcatccgcg
     2641 cgcgcaaaat ggctgacgat attcaccggc tgacgaacgt ttttgcactg ggtcaggcga
     2701 tgataaaacg cctcagcctg ttccggcctt acgcccagac ggtgcatacc ggtatcgagt
     2761 ttcatccaga cggtaaccgg ctcgtccagg ctagcctctt ccagcgcagc cagctgttct
     2821 tcgttatgca cggcggtatg aaaatgttgc gcagaaatcg tcggcagatc tctggcatca
     2881 aaaaagcctt cgagtaacag tacaggtttg gtgattcccc ccgcacgcag tcgcagagct
     2941 tcttcgagac gggctacgcc aaaggcgtca gcatcgggga gcgttcgcgc ggtctcaaga
     3001 agaccgtgac cataagcgtt cgctttcacc accgcaacca ttttactggc aggggccagt
     3061 tcacgaagac gttgcaggtt gtgtcgcaga gcgcggcggt taatcacaac agttgccgct
     3121 tgcatttgtg ttccttgata agtgtttgct ttaattacct aattcataaa ataattatta
     3181 ttcgtcgtcg tactgcggcc ccgcatagtt gtcgaagcgc gaccattgac cgttaaaggt
     3241 caggcgtacc gtcccgattg ggccgttacg ttgtttaccg ataataattt ccgcgatgcc
     3301 ttttaaatca ctgttttcgt gatacacctc atcacgatag ataaacatga tcaagtccgc
     3361 atcctgctcg atagagccag attcacgcag gtcggagttg accgggcgtt tgtcggcacg
     3421 ttgttccaga gaacggttca actgggacag cgccaccacc ggcacgttca gttctttcgc
     3481 cagtgctttc agcgagcgag agatttctgc aatttccagc gtacggttat cggaaagcgc
     3541 cggtacgcgc atcagttgca ggtagtcgat catgataagc ccgatgccgc cgtgttcacg
     3601 ggcaatacgg cgtgcgcggg aacgcacttc cgttggcgtc aggccggagg agtcatcgat
     3661 atagatattg cgtttttcga gcaaaatacc catggtgccg gaaatgcgcg cccagtcttc
     3721 atcatcgagc tgcccggtac ggattttagt ctggtcaacg cgcgacagcg acgccagaga
     3781 acgcatcata atctgttctg aaggcatctc cagcgagaag ataagtactg gtttatcctg
     3841 caacatcgcc gcgttttcga cgaggttcat cgcaaatgtt gttttaccca tcgacggacg
     3901 cgcggcgacg atgatcaaat ccgacggctg caagccagcg gtttttttgt tgagatcgtc
     3961 ataaccggtg tttactccgg taacgccatc gtgtggctgc tgaaacaact gctcaatacg
     4021 cgccacggtt gcgtcgagca catcggcgat gttcttcggc ccttcgtctt tgtttgcacg
     4081 actttcggca attttaaaga cgcgggattc agcaaggtcc agcagatctt cgctggtacg
     4141 cccctgcgga tcaaaaccgg cttcagcaat ctcattcgca accgagatca tctcacggac
     4201 aacggcacgt tcacgcacga tgtcagcata agcactgatg ttcgccgcac ttggcgtatt
     4261 ttttgacagc tctgccagat aagcaaaacc accgacgcta tcgagttgcc cctggcgttc
     4321 cagcgattcc gcaagagtaa ttagatcgat agggctaccg ctttcctgca aacgcgccat
     4381 ttcagtaaag atatgacggt gtgggcgggt gtaaaaatcg tctgctacca cacgctcggc
     4441 tacatcatcc cagcgttcgt tatctagcat taaaccgccc aacaccgact gctccgcttc
     4501 gatcgagtgc ggaggcactt tcagcccggc aacttgtgga tcgcgttcgc ggggttcagc
     4561 ctgctgtttg ttgaagggtt tatttcctgc catagtgaat ggagttaccg agataaagaa
     4621 tgggtcgaaa ctttaccata tgaagcagac cctgacgata cgttctggag gacacatggc
     4681 aacacgaatt gaatttcaca agcacggtgg cccggaagta cttcaagccg tagagttcac
     4741 tcctgccgat ccggcggaga atgaaatcca ggtcgaaaat aaagccatcg gcatcaattt
     4801 tatcgacaca tatatccgca gcggccttta cccgccgcca tcgctaccca gcggattagg
     4861 caccgaagca gcaggcatcg tgagtaaagt cggcagtggt gtaaagcata ttaaggcagg
     4921 cgatcgtgta gtctatgcgc agtcggcgtt aggcgcttac agctctgtgc ataacattat
     4981 tgcggataaa gcggcgattc tgcctgcggc aatttctttt gagcaagctg cggcatcctt
     5041 cctgaaaggc ttaacggttt attatctgct gcgcaaaacc tatgaaatta aacccgatga
     5101 gcagttcctg ttccacgcag cagctggcgg cgttggcttg attgcctgcc agtgggcaaa
     5161 agccctgggc gcgaaactta tcggcaccgt aggaaccgcg caaaaagcgc agagcgcgct
     5221 aaaagcgggc gcgtggcagg ttattaacta tcgtgaagag aatctggtcg agcggttaaa
     5281 agagatcacc ggcggtaaga aagtgcgcgt ggtgtacgat tccgtgggca gagacacctg
     5341 ggaacggtcg ctggattgcc tgcaacgccg cggcttaatg gtgagttttg gcaactcatc
     5401 aggtgcggtt accggtgtga acttaggcat tctcaatcag aaaggctcgt tgtatgtgac
     5461 acgcccttcc ctgcaaggct atatcaccac gcgggaggaa ttaaccgagg ccagtaatga
     5521 actgttctct ttgattgcca gcggtgtgat taaggtcgat gtcgccgagc agcagaaata
     5581 tccgctgaag gatgcgcagc gtgcgcatga aattctggaa agccgggcaa cgcaaggttc
     5641 cagcctgttg attccataaa agaaataggg cttccacctg ggaagccctt tctttttata
     5701 gttcggctgt atgtagggta cagcacgatg aatctgttag aggcgcaata gtgacagatt
     5761 tgattatcaa ttcctatttt gttctaagga taaaacctta ggttgtgatc atccgcacaa
     5821 tcccttagta acgccagcgg tcataacgct gatatttcgg cacttttggt gctttaatcg
     5881 ccttaataac ccacaccacc gcaatcgcca gtagtaacca cggcagcaac ttaatcatca
     5941 atgccagcat accgccgagg aacataatgg ccgtcgccac aaccagcgcg gcgataatgc
     6001 ccagcaacga aacgccggtg accatcagca tgacaaaaaa gccaatcaca aaaagtagtt
     6061 ccagcatgat gcactcccaa atatgaaatc tcttgctggc attacaagaa tcatgccaaa
     6121 aataatctat tgatttaaca gcaaaacgcc ccgcgacggt gcgcagggcg tggtgaattt
     6181 gactattttt tggtgaaaag ttaacgctta tccgccacca gtttgagcgc gtgttccagc
     6241 acattaatgt ctgcacccgc tttatgggca ttttcactta aataacgccg ccactgccgc
     6301 gcgccaggaa taccctggaa caagcccaac atatgccggg taatatgacc gagatacgtc
     6361 ccctggctga gttcacgctc aatgtacgga tacatggcgc gcactaccgc caccggatcg
     6421 gcatcgatat ccgaggaacc aaagatctcc cggtctaccg ccgccagaat acccggattc
     6481 tgatacgcct cgcgcccgac catcacgcca tccatatgtt gcaggtgtgc tttggcctct
     6541 tccagcgact tgataccacc gttaatcgac attgtcagat gcggaaagtc acgcttcagt
     6601 tgatacacac gcggataatc gagcggcggg atctcacggt tttctttcgg acttaacccc
     6661 gaaagccagg ctttacgtgc atggatgatg aacatctcac actcgccttt gccggaaacg
     6721 gtgttgatga aatcgcagag aaattcatag ctgtcctggt cgtcgatgcc aatacgcgtt
     6781 ttcaccgtca ccggaatcga caccacatcg cgcatcgctt tcacgcagtc ggcaaccagc
     6841 tgcgcattac ccatcagaca cgcaccaaac atgccgttct gcacccggtc agacgggcag
     6901 ccgacattca ggttgatctc atcatatcca cgcgcttctg ccagcttcgc acactgcgcc
     6961 agcgccgccg gatcgctacc gccgagttgc aacgctaccg gatgttcttc ttcactatac
     7021 gccaggtaat cacctttacc gtgaataatc gcccctgtag ttaccatttc agtatacagc
     7081 aacgtattgc gggaaagcag acgcaagaaa tagcggcaat gtctgtccgt ccagtcgagc
     7141 attggtgcaa cgctaaaccg accactccag tgaacgtcag ttttttcagg cattgcgctg
     7201 gtttggttga ttttttgcat ttcagaatta ccgtgcattt tcaaatgtag agattatttt
     7261 atcgatatat catggggtta tgttattcag catcactgtt caggaggctc aatagcgggg
     7321 tactatacca taacaacagg aagcgcctgt ctcattgcaa aagaaaattg agatcctctc
     7381 aaggcatgaa gctctcacga agtgatggaa ataatcttat tagccgttaa ctttgttaag
     7441 gccaatgata aacaatccag gttcgacgat aaataaaaaa tcacacatta aactctggtg
     7501 atatatctcc ctgctaatag cattgataga gaaaaaagaa cccaataaat attgggtcct
     7561 tttatataat gccttccata ctatcgaaga acttcacata ttatttctcc gatttaaccc
     7621 cgaacaaatc ataaattaat ttagaagtgt ctgtaagtat tttaatctct tcctttgagg
     7681 ttgggtcaaa cgacttcgcg aagctaatta attgtggtgc agcatctcgc attttgctta
     7741 aaatatcagg atcgagcgtt ccttcattca ccagatgtga catcttatcc agatagccat
     7801 caaaattcat ttctccccca tcagccagac gcttcatctc tcccaggtac ttcttcatat
     7861 cacgttgaga taatttttca aactgagctt tcaggtagct ctcattattt tcattaatat
     7921 acactgtttc tgataaatct gcgtaggcac tagaatatga aagtgaaatt aacagcgaag
     7981 caaataattt taagctgttg tcatcatgtt cctggcaggc attaacaaac gttaaaaaac
     8041 cagaacctat tgcttgaaaa tgtatattcg ctaaaggttc attatcctta gattcctcat
     8101 aaaatagctg aaccgtggag ggaaggtcat tcttagtttc tacatcaaaa gtacattgtt
     8161 caatgggcat tgcatcttta ttatccccaa gattacatat actattaatc gcgaaatgaa
     8221 aaatagcccg gtcaacaact gatgcaataa agtcacgatc gtttaaatcc tcatcagtgc
     8281 aatcgtcaat atacttattg acccacattt tgagatcatt tatttgctca attaaaaaca
     8341 cattttttta cgtgcatgcc ataaattatg cgtgattcgt tgaataaaca aatctatttt
     8401 tgcaataatt atatcccgat gacgca
//
LOCUS       DAPHKZ010000171         8405 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.172, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000171 DAPHKZ010000000
VERSION     DAPHKZ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8405
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.172"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(140..4027)
                     /gene="purL"
                     /locus_tag="RH288_004188"
                     /gene_synonym="purI"
     CDS             complement(140..4027)
                     /gene="purL"
                     /locus_tag="RH288_004188"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDV4033177.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLN
                     APLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     VNRLERGVAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTS
                     VDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWIIDGEQQPKSLFRMIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHE
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGD
                     ALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAV
                     TTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPL
                     SLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGIDADIATLGD
                     DRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSGDRFVITANGQT
                     VFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVA
                     APYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRTGLEDFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPE
                     RVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG"
     gene            4285..5841
                     /gene="mltF"
                     /locus_tag="RH288_004189"
     CDS             4285..5841
                     /gene="mltF"
                     /locus_tag="RH288_004189"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HDV4033178.1"
                     /translation="MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGE
                     LRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
                     VNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELA
                     VALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVD
                     TRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLT
                     KNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHML
                     DARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLF
                     SRKGSEEKQN"
     gene            complement(5838..6374)
                     /gene="tadA"
                     /locus_tag="RH288_004190"
     CDS             complement(5838..6374)
                     /gene="tadA"
                     /locus_tag="RH288_004190"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDV4033179.1"
                     /translation="MRRAFITGVFFLSEVEFSHEYWMRHALTLAKRAWDEREVPVGAV
                     LVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCA
                     GAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFF
                     RMRRQEIKAQKKAQSSTD"
     gene            complement(6399..7034)
                     /gene="yfhb"
                     /locus_tag="RH288_004191"
     CDS             complement(6399..7034)
                     /gene="yfhb"
                     /locus_tag="RH288_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417055.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HDV4033180.1"
                     /translation="MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIAIALLIKGRAARWPMSLLLWGCTFGHSEARLQTLQADFVRWFRDNVTAFPLVQE
                     RLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE"
     gene            7243..8091
                     /locus_tag="RH288_004192"
     CDS             7243..8091
                     /locus_tag="RH288_004192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDV4033181.1"
                     /translation="MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEA
                     GVSQSSVVKFAQKLGYKGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKL
                     IKENTAAMYATLNVNSEEKLHECVTMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
                     AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPN
                     ALQQRASHCLYTIAEEQATNSASISACHAQGMLTDLLFIALIQQDLELAPERIRHSEA
                     LVKKLV"
     gene            8147..>8405
                     /locus_tag="RH288_004193"
     CDS             8147..>8405
                     /locus_tag="RH288_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhL family 4Fe-4S dicluster ferredoxin"
                     /protein_id="HDV4033182.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGDHIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTIVKDPAHVETEEQLWDKFVLMHHADKI"
BASE COUNT         2030 a         2314 c         2171 g         1890 t
ORIGIN      
        1 aagtgtcgcc agaaagcgac acggcaaacc acccattgtc gtgatttaca gacacaaaaa
       61 agctcccgga gttgggagct tatgatagtg gttggtgctt aatgccgcat ccgggctgca
      121 aaaccaatgg gctgacgact taccccaact gcttacgcgc attgcggaaa atgcgcatcc
      181 atgggccatc ctcgccccag ttttccggat gccaggagtt gctgacagta cggaaaacac
      241 gttccgggtg cggcatcata atggtgactc gaccactttc agtcgtgact gccgtaatac
      301 cgttcggtga accgttcggg ttagccgggt aggtttcagt gactttgccg aagttatcga
      361 catagcgcag tgccaccagc cctttgcttt ccagtgccgc cagatgcgcc gcatcacgca
      421 cttccacgcg cccttcacca tgagagacag caatcggcat ttgcgagccc accatcccct
      481 gcaacagcag agacgggctt tgggttactt caaccaggct gaaacgcgct tcaaagcgat
      541 cggaggtatt gcgcacaaaa cgtggccaca actcactacc tgggatcagt tcacgcagat
      601 tagacatcat ctggcaaccg ttacataccc ccagcgccag cgtttgcgga cggtggaaga
      661 aggttgcaaa ctcatcgcgt acacggtcat tgaacaggat tgacttcgcc caaccttcac
      721 cggcacccag cacatcaccg taggagaaac caccgcacgc gaccagggcg tggaaatctt
      781 ccaggcccgt gcgtccggtc agcaggtcac tcatatgcac gtcgatagca tcaaagcctg
      841 cacggtggaa agctgccgcc atttcaacat gcgagttcac gccctgctca cgcagtacgg
      901 caactttcgg acgtgcgcca gtggcaatat acggtgctgc cacatcttcg ttgatatcga
      961 acgacagttt tacattcagg cccggatcgg cgtcgttaga tttcgcctga tgctcctgat
     1021 cggcacactc cgggttgtca cgcaggcgct gcatctgcca ggtagtttct gcccaccaga
     1081 cacgcaacgt ggtgcggctt tcgctgaata cagtctgccc gttggcggta atcacaaaac
     1141 ggtcaccgga aaccgcctgc cctacataat ggacacaatc agcaagccca tgctgtgcca
     1201 gtacggactc gaccgcttca cggtcagcgg cacgaacctg aatcaccgca cccagttctt
     1261 cgttaaacaa cgccgccagg cgatcgtcac ccagagtggc gatatccgcg tcaatgccac
     1321 aatgaccagc aaaggccatt tccgccagcg ttaccagcag gccgccatca gagcggtcgt
     1381 gatacgccag cagcttacgc tgtgcaacca gcgcctgaat cgcgtcatag aagcctttca
     1441 gttgcgcgac atcgcgtaca tctgccggtt tgtcgccaag ctgacgataa acctgcgcca
     1501 gcgccgttgc gcccagcgcg ttattgcctt tgcccaaatc aatcagcagc agtgcgttat
     1561 cttcggtaga aagctgcggc gtgatggtgt gacgtacatc ttccacgcgg gcaaatgcag
     1621 aaatcaccag cgacagcggc gacgtcattt cgcgctcttc gttaccttcc tgccagcggg
     1681 ttttcatcga catggagtct ttacccaccg ggatcgtcag gcccagcgcc ggacaaagct
     1741 cttcgcccac ggctttaacg gcttcataca ggcccgcatc ttcaccaggg tggcctgccg
     1801 ccgccatcca gttggcggaa agtttgatgc gtttgatatc gccaatttgt gttgcggcga
     1861 tgttggttaa cgcttcaccg accgccagac gggcagaggc ggcgaaatcc agcagcgcaa
     1921 ccggcgcacg ctcgccaatc gccatcgctt caccgtagta gctgtcgagg ctggcggtag
     1981 tgaccgcgca gttagcgacc ggcacctgcc acggccccac catctgatcg cgcgctacca
     2041 tgccggttac gctgcggtcg ccaatggtca ccaggaaggt tttttccgcc acagtcggca
     2101 gatgcagcac acgtttcacc gcgtctgcaa tggtgatccc ttcacgggcc agcgcgtcgc
     2161 ctttcgcttt cagcgtttgt acatcgcggg tcatcttcgg cgttttacca agcaggacgt
     2221 ccagcggcag atcgatcggc tgattatcaa aatgacgatc gtgcagagaa agatgcagtt
     2281 cttcggtcgc ttcaccaatc acagcgtagg gtgcgcgctc acgcttacac agctcgtcaa
     2341 acagcggtaa ttgatcagca gcaaccgcca gcacgtagcg ttcctgggat tcgttacacc
     2401 agatttccag cgggctcatg cccggttcgt cgctcaggat atcgcgcagt tcgaatttac
     2461 cgccgcgccc gccgtcgctc accagttccg gcatggcgtt agaaagaccg cccgcaccga
     2521 cgtcgtggat aaacagaatt gggttagcat caccaagctg ccagcaacgg tcgattactt
     2581 cctggcaacg acgctccatc tccgggttgt cgcgctgtac ggaagcaaag tcgaggtcgg
     2641 catcagactg acctgacgcc atggaagacg ccgctccgcc gccaagaccg atgttcattg
     2701 ccgggccgcc gagaacgacc agcttcgcac cgacgttgat ctcgcctttt tgtacgtgat
     2761 cggcgcgaat gttgccgatc ccgcccgcca gcatgatcgg tttgtgataa ccgcgcagct
     2821 cttcgccgtt gtggctgttc actttttctt cataagtacg gaagtagcca ttcagtgccg
     2881 gacgaccaaa ttcgttgtta aacgccgcgc cgcccagcgg gccttcggtc atgatgtcca
     2941 gcgcggtgac aatgcgctca ggcttaccga aatcttcttc ccacggctgt tcgaagccag
     3001 gaattcgcag gttggaaacg gagaaaccaa ccagaccagc cttcggcttc gcaccgcgtc
     3061 cggtggcgcc ttcatcacga atttcgccgc cggaacccgt cgccgcgccc ggccacggag
     3121 aaatcgccgt cgggtggttg tgagtttcga ctttcatcag aatatgcgcc ggttcctgat
     3181 ggaaatcgta gcggcccgtt tcgtggtcag caaagtagcg gcccacttca gaaccttcca
     3241 ttacggcggc gttatcttta taagcagaga gaacgtgatc tggcgtggtt tcgaaagtat
     3301 ttttgatcat cctgaacagc gatttcggct gctgttcacc gtcgataatc cagtcggcat
     3361 taaaaatttt gtggcggcag tgctcagagt tcgcctgagc gaacatatac agctcgatgt
     3421 cgttcgggtt acgaccaagc tttgtgaaag catcctgcag atagtcaatt tcatcttccg
     3481 ccagagccaa gccaagacgc aggttagcgt cgatcagcgc ctgacggccc tgccccagca
     3541 aatcaacgct ggtaaccgga gtcggttgat ggtgggcaaa caactgctct gcatcatcta
     3601 aagcaaaaaa gaccgtttcc atcatgcggt cgtgcagttc agcggtaacc tgctgccatt
     3661 gttcattggt cagcgtaccg gcttctatat agtaagcaac gccgcgctca aggcggttta
     3721 cctgttgtag cccgcagtta tgggcaatat cggtcgcttt cgaagaccag ggagagatgg
     3781 tgccaggacg cggggtcacc agcaggagtt tgccttgcgg ggcgtggctg gcgagtgccg
     3841 ggccatattt cagcaggcgt tcaagttgtg cgtgctcatc atcgtttaac ggcgcattga
     3901 ggtcagcaaa atggacatac tcggcgtaaa tattgtgaac cgggagcctg gcagcctgaa
     3961 aacgtgccag cagtttgttg attcggaatg ccgacagtgc aggcgaacca cgcagaattt
     4021 ccatcataag tctctcgtct tctaagcttt cggtgtaccc aaggggggga aacgggcgtc
     4081 attataaaga atctgatgcg ctgacgaaac cgtttgcgtg gaaataaaat caccatcgtg
     4141 aattagcaac gcgtgccgcc aatggctgta ataagttgcc atctggcgca ggtttacgca
     4201 aaatgccgct catttatgag taaacctttc actattatta cgttttttca agctgggacg
     4261 cgcacgacac agagaattaa ctaattgaaa aaattaaaga ttaattatct gttcatcggc
     4321 attctggcac tgctgctcgc ggtcgctctc tggccatcca ttccctggtt tggtaaagcc
     4381 gacaaccgta tcgccgccat tcaagcgcgg ggagagttgc gtgtgagcac cattcatact
     4441 cccctgactt ataacgaaat caacgggaaa ccttttggcc tggattacga actggcgaaa
     4501 cagtttgccg attacctcgg cgtaaaactg aaagtgaccg tgcggcagaa tatcagccag
     4561 ctgtttgacg accttgataa tggtaacgcc gacctgctgg cggcaggact tgtctataac
     4621 agtgagcggg taaaaaatta tcagcctggc cctacctatt attccgtgtc acaacaactg
     4681 gtttataaag tgggtcagta tcgcccacgt acgctgggca acctgacggc ggagcaactc
     4741 accgttgcac cgggtcatgt ggtggttaac gatctccaga ccctgaaaga aacaaaattc
     4801 ccggaattaa gctggaaggt agacgacaaa aaaggctctg cggaattaat ggaagatgtc
     4861 atcgaaggaa aactcgatta caccattgct gattctgtcg ccatcagcct gtttcagcgc
     4921 gttcacccgg agctcgccgt agcgctcgat atcaccgatg aacaaccggt gacttggttt
     4981 agcccgttag atggcgataa taccctttcc gccgccctgc tcgacttctt caacgaaatg
     5041 aatgaagacg gtacgctggc acgcattgaa gagaaatacc tggggcatgg cgatgatttt
     5101 gattacgtcg atacgcgcac atttttacgc gccgtcgatg cggtactgcc gcagttaaag
     5161 cccctgtttg agaaatacgc cgaagaaatt gactggcgtt tgctggccgc tattgcttat
     5221 caggaatcgc actgggatgc acaggccact tcaccgacgg gtgtgcgcgg catgatgatg
     5281 ttaaccaaaa ataccgcgca aagcctcggc attacggatc gtaccgatgc cgaacagagc
     5341 atcagcggtg gcgtgcgtta tttgcaggat atgatgagta aagtgccgga aagtgtgccg
     5401 gagaacgagc ggatctggtt tgccctcgct gcgtacaata tgggctatgc gcatatgctg
     5461 gatgcccgcg ccctgacggc aaaaaccaaa gggaatcctg acagttgggc tgacgtaaaa
     5521 cagcgtctgc ctttacttag ccagaaaccc tattacagca agctgactta cggctacgct
     5581 cgtggacatg aagcctacgc ttatgtcgaa aatattcgta agtatcagat tagcctggtg
     5641 ggttatctgc aagagaaaga gaagcaggct acagaagcgg cgatgcaact ggcgcaggat
     5701 tatccggcgg tatcgcctac ggagttgggc aaagagaaat ttccttttct ctcgtttctt
     5761 tcccagtcgt catcaaacta tttgacccat tctccctctc tgctgttttc caggaaaggg
     5821 agtgaagaga aacaaaatta atccgtcgag gattgcgctt ttttctgcgc tttaatttcc
     5881 tggcggcgca tgcgaaagaa gtcactgagc aacgccgcgc actcatccgc cagtattcct
     5941 tccgtaattt ccactcggtg attcataccc ggatgatgca gcacatccat taaagatccc
     6001 gcagcgccag ttttcgcgtc acgcgcacca aagaccacgc gaccaatgcg actgtggatc
     6061 atcgctccgg cacacattac acatggttca agcgtgacat acaacgtggc gtcgatcaga
     6121 cgataatttt gcatcaccag accaccctgc cgcagggcca tgatttctgc atgtgcggtg
     6181 ggatcatggc gaccaatcgg gcggttccag ccttcgccga ttacccgatt gttatgcact
     6241 aataccgcgc cgaccggcac ttcccgctca tcccaggcac gtttcgccag cgtcagcgcg
     6301 tgacgcatcc agtattcgtg gctaaattcg acttcagaca aaaagaaaac tccggttata
     6361 aaagcgcggc gcattataca cggacgctat gctttactct attccagttg ctggagttca
     6421 ccgcgcgggg ttactcgcca acgatgctga cagaaataaa gcagcggatt gtcctgatta
     6481 ctgtcgctat agccactgta cagccgcagc ggagtgccga ttttgcgctc cagttgtgcg
     6541 accttttcat gtcccagaca acgcatcgtc aatacccaac caccatagcc acgctgaatt
     6601 tggctggcga taagattaac ccgcggcagc cagggcgtat cgaaataaac cgcttcaacc
     6661 agcggctgcg gagagccggt aatcaaccag atatcagcat cggaacttaa caggtaggtg
     6721 gttaatcgct cctgaaccag cggaaaggcg gtaacattgt cgcgaaacca gcgcacgaaa
     6781 tcggcctgca acgtctgtaa acgtgcttcg ctgtgaccaa aagtgcaccc ccacagaagc
     6841 agactcatcg gccagcgtgc cgcacgacct tttatcaata acgcaatggc tataatcggt
     6901 aacaacggca ggacaagtaa cgcattcagc ggttggcgac gtagtaaata gcgcagaaaa
     6961 ctgccgaaca tatcctgctg atgcaatgtt ccatctaagt caaaaaacac cacacgacgc
     7021 tcgtgagttg ccaaaccata ctcctctgga ctgaaacatc ctgattaatt ttcgctacta
     7081 catagcctaa cagatagatc atcacttttc cggcaacaat cgaccgcatc atggctaact
     7141 ggaattttta attcatggca attagcggca atggaatata aaattcactc gcgtgtgtct
     7201 catattgcct gttgtcgcca ctatttcatc gcgaggaaag atatgaacgg cttacttcgt
     7261 atccgtcagc gttaccaggg gcttgcccag agtgataaaa aactggcgga ttatctgctg
     7321 ctacaacctg atacggcgcg ccatttaagc tctcagcaac tggccaacga agccggagtc
     7381 agtcagtcca gcgtcgtgaa gttcgcgcaa aaactcggct ataaaggttt tccggcgctt
     7441 aagttggcgt tgagtgaagc gctggcaagc cagccggaat caccctccgt gcccattcat
     7501 aaccaaatcc gcggtgatga tccgttacgg ctggtcggcg aaaaactgat taaagaaaat
     7561 actgccgcta tgtacgcaac gctaaacgtt aatagtgaag agaaactgca tgaatgcgta
     7621 acaatgttgc gctctgcgcg gcggataatt ctgaccggta ttggcgcttc gggtctggtg
     7681 gcgcaaaact ttgcctggaa gctgatgaag attggcttca atgctgccgc agtgcgcgat
     7741 atgcatgcgc tactcgcaac agtacaggcg tcgtcccctg acgatctgtt attagccatt
     7801 tcctacaccg gtgtacgacg cgagttaaac ctggcggcag atgagatgct gcgagtgggc
     7861 ggaaaagtgc tggcgattac cggctttact ccgaatgccc tgcaacagcg tgcttctcat
     7921 tgcctgtata ccattgccga agaacaagcg acaaacagtg cttcaatctc tgcttgtcac
     7981 gctcagggaa tgttaacgga tttgctgttc attgcgctga ttcagcagga tctggaactg
     8041 gcaccagaac gtattcgtca tagtgaagcg ctggtgaaaa aactggtctg agtaaagaat
     8101 gcgcgtataa tgcccgcccg gtttgtgttg ttttgagagt ttccttatgg cgttgttaat
     8161 cactaaaaaa tgcatcaatt gtgatatgtg tgaacccgaa tgcccgaatg aggcgatttc
     8221 aatgggagat catatctacg agattaacag cgataagtgt accgaatgcg tagggcacta
     8281 cgagacacca acctgccaga aggtgtgccc gatccccaat actattgtga aagatccggc
     8341 gcatgtcgag acagaagaac agttgtggga taaatttgtg ctgatgcacc acgcggataa
     8401 aattt
//
LOCUS       DAPHKZ010000172         8357 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.173, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000172 DAPHKZ010000000
VERSION     DAPHKZ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8357
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.173"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            306..1283
                     /gene="csiD"
                     /locus_tag="RH288_004194"
     CDS             306..1283
                     /gene="csiD"
                     /locus_tag="RH288_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417145.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HDV4033183.1"
                     /translation="MNALTAVQNNAVDSGQDYSGFTLTPSAQSPRLLELTFTEQTTKQ
                     FLEQVAEWPVQALEYKSFLRFRVAKILDDLCANQLQPLLLKTLLNRAEGALLINAVGV
                     DDVKQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDNYFRHPLARRPMRFAAPP
                     SKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYASNHYQTHQ"
     gene            1303..2571
                     /gene="lhgO"
                     /locus_tag="RH288_004195"
     CDS             1303..2571
                     /gene="lhgO"
                     /locus_tag="RH288_004195"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417146.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HDV4033184.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESGPACHQTG
                     HNSGVIHAGVYYTPGSLKAQFCLAGNRATKAFCDQNGIRYDNCGKMLVATSDLEMERM
                     RALWERTAANGIEREWLNVDELREREPNITGLGGIFVPSSGIVSYRDVTAAMAKIFQS
                     RGGEIIYNAEVSGLNEHKNGVVIRTRQGGEYEASTLISCSGLMADRLVKMLGLEPGFI
                     ICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKR
                     EGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLS
                     LSDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSK
                     VQTLLASQSNPGRTLRAARSVDALHAAFNQ"
     gene            2594..4042
                     /gene="gabD"
                     /locus_tag="RH288_004196"
     CDS             2594..4042
                     /gene="gabD"
                     /locus_tag="RH288_004196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HDV4033185.1"
                     /translation="MKLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPK
                     MGADETRAAIDAANRALPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGN
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGDGLDNGVTIGPLIDE
                     KAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLA
                     PLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            4056..5336
                     /gene="gabT"
                     /locus_tag="RH288_004197"
     CDS             4056..5336
                     /gene="gabT"
                     /locus_tag="RH288_004197"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HDV4033186.1"
                     /translation="MNSNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
                     LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYASS
                     PAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPL
                     AGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANDLGQKLKDG
                     LLAIAEKHPEIGDVRGLGAMIAIELFEDGDHNKPDAKLTAEIVARARDKGLILLSCGP
                     YYNVLRILVPLTIEDAQIRQGLEIISQCFDEAKQ"
     gene            5574..6974
                     /gene="gabP"
                     /locus_tag="RH288_004198"
     CDS             5574..6974
                     /gene="gabP"
                     /locus_tag="RH288_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HDV4033187.1"
                     /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFW
                     VLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
                     IAILAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSV
                     LELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTP
                     YVAVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAE
                     GSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMAR
                     WKKLVLWQKTPVHNTR"
     gene            6995..7657
                     /gene="csiR"
                     /locus_tag="RH288_004199"
     CDS             6995..7657
                     /gene="csiR"
                     /locus_tag="RH288_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HDV4033188.1"
                     /translation="MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLR
                     EALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEA
                     DVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSHYLLQMRERLFDLAAR
                     YRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMA
                     GN"
     gene            complement(7658..8107)
                     /gene="kbp"
                     /locus_tag="RH288_004200"
     CDS             complement(7658..8107)
                     /gene="kbp"
                     /locus_tag="RH288_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium binding protein Kbp"
                     /protein_id="HDV4033189.1"
                     /translation="MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLNKTGIPDAD
                     KVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTATPATASQFYTVK
                     SGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE"
     gene            complement(8191..8349)
                     /locus_tag="RH288_004201"
     CDS             complement(8191..8349)
                     /locus_tag="RH288_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HDV4033190.1"
                     /translation="MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIH
                     AFWVQTRD"
BASE COUNT         1850 a         2216 c         2358 g         1933 t
ORIGIN      
        1 ggcagataat atgtttagtt tactaacggt cattttgcag tgaagccatt tactgttttt
       61 tatcgaccag ataatctgtt ctctaatgtt aactccccct aacctgttgc tttagttatt
      121 catttcctgt ctcactttgc cttaataccc tacgttaaat gttactaatt tgttgctttt
      181 gatcacaata agaaaacaat atgtcgcttt tgtgcgcatt tttcagaaat gtagatattt
      241 ttagattatg gctacgaaat gagcatcgcc atgtcaccct acatctcata agaggatcgc
      301 ttctgatgaa tgcactgacc gccgtacaaa ataacgctgt cgattcaggc caggactata
      361 gcggattcac cctcaccccg tcggcgcaat ccccgcgtct gctggaactc accttcaccg
      421 aacagacgac caaacagttt cttgagcagg ttgccgagtg gcccgtgcag gcgctggagt
      481 acaaatcgtt tctgcgtttt cgggtagcca aaattcttga cgatctatgt gcgaaccagc
      541 tgcaaccatt gctgttgaag acgttgctaa accgcgctga aggtgcgttg ttgatcaatg
      601 cggtgggtgt cgatgatgtg aagcaagcgg atgagatggt gaagctggcg acggcggtgg
      661 cgcatctgat tggccgttcc aatttcgatg cgatgagcgg tcagtattac gcgcgttttg
      721 tagtgaaaaa tgtcgataac tcagacagct atctgcgcca gccgcaccgc gtgatggagc
      781 tacacaacga cggcacgtat gtcgaagaga taaccgatta cgtgctgatg atgaaaatcg
      841 acgagcaaaa catgcagggc ggaaattcgc tgctgctgca tctcgatgac tgggaacatc
      901 tcgacaacta tttccgccac ccgctggcgc gtcgcccgat gcgctttgcc gcgccgccga
      961 gtaaaaacgt cagcaaagat gtttttcatc cggtgttcga cgtcgatcaa cagggtcgcc
     1021 cggtgatgcg ctatatcgac cagttcgtcc agccgaaaga cttcgaagaa ggcgtgtggt
     1081 tgagcgagct ttccgacgcc attgaaacca gcaaaggcat tctttctgtg cccgttcccg
     1141 ttggcaaatt cctgttgatt aacaacctgt tctggctgca cggtcgcgac cgctttactc
     1201 cgcacccgga tctgcgccgt gaactgatgc gccagcgtgg ctatttcgct tacgcctcta
     1261 accactacca gacgcatcag taagcgcaaa ggaattgagc ggatgtatga ttttgtgatt
     1321 attggcggcg gcatcatcgg catgtcgacc gccatgcaac tgattgatgt ctatccggac
     1381 gcccgcattg cgttgctgga aaaagagtcc ggcccggcct gtcaccagac gggccacaac
     1441 agcggcgtga tccatgccgg ggtctattac acgcccggca gcctgaaggc gcagttttgc
     1501 ctggcgggaa accgcgccac caaagccttt tgcgatcaaa acggcattcg ctacgacaac
     1561 tgcggcaaga tgctggttgc cacgtccgat ctcgaaatgg aacggatgcg cgccttatgg
     1621 gaacgcacag cggcgaacgg tatcgagcgc gaatggctta acgtcgacga actgcgcgag
     1681 cgcgaaccga atatcaccgg gctcggcggc atttttgtgc cgtccagcgg cattgtcagc
     1741 taccgcgacg tgacggcggc gatggcaaaa atcttccagt ccagaggcgg tgaaattatc
     1801 tataacgccg aagtcagcgg gcttaatgag cataaaaacg gcgtggtgat acgtacccgt
     1861 cagggcggcg aatatgaagc atcaacgctg attagctgtt ccgggctgat ggctgaccgg
     1921 ctggtgaaaa tgctcggact cgaaccgggc tttatcatct gcccgttccg tggcgagtat
     1981 ttccgccttg cgccggagca taaccagatt gttaaccacc tgatttaccc cattcccgac
     2041 ccggcaatgc cgtttttggg cgttcatctc acccgcatga tcgacggcag cgtgaccgtc
     2101 gggccaaacg cggtgctggc tttcaaacgc gaaggctatc gcaagcgcga cttctcattt
     2161 agcgacacgc tggagatttt gggctcgtcg gggattcgcc gggtgctgca aaaccatcta
     2221 cgctcaggac tgggcgagat gaaaaactcg ctgtgcaaaa gcggctatct gcggctggtg
     2281 caaaagtatt gtccccggct ttcgttaagc gatctccagc cctggcccgc cggtgtgcgg
     2341 gcgcaggcgg tatcgccgga cggcaagctg attgacgatt ttctgtttgt caccaccccg
     2401 cgcacgatcc acacctgcaa tgcgccctcc ccggcagcga catcagcaat tcctattggt
     2461 gcgcatattg tcagcaaggt acaaacgctg ttggcaagcc agagtaaccc cggacgcacg
     2521 ctgcgagcgg cacgtagtgt ggatgcctta cacgccgcat ttaatcaata acctttgaaa
     2581 acaggatgta gcgatgaaac ttaacgacag taacttattc cgccagcagg cgttgattaa
     2641 cggggaatgg ctggacgcca acaatggtga agccatcgac gtcaccaatc cggcgaacgg
     2701 cgacaagctg ggtagcgtgc cgaaaatggg cgcggatgaa acccgcgccg ctatcgacgc
     2761 cgccaaccgc gccctgcccg cctggcgcgc gctcaccgcc aaagaacgcg ccaccattct
     2821 gcgcaactgg ttcaatttga tgatggagca tcaggacgat ttagcgcgcc tgatgaccct
     2881 cgaacagggt aaaccactgg ccgaagcgaa aggcgaaatc agctacgccg cctcctttat
     2941 tgagtggttt gccgaagaag gcaaacgcat ttatggcgac accattcctg gtcatcaggc
     3001 cgataaacgc ctgattgtta tcaagcagcc gattggcgtc accgcggcta tcacgccgtg
     3061 gaacttcccg gcggcgatga ttacccgcaa agccggtccg gcgctggcag caggctgcac
     3121 catggtgctg aagcccgcca gtcagacgcc gttctctgcg ctggcgctgg cggagctggc
     3181 gatccgcgcg ggcgttccgg ctggggtatt taacgtggtc accggttcgg cgggcgcggt
     3241 cggtaacgaa ctgaccagta acccgctggt gcgcaaactg tcgtttaccg gttcgaccga
     3301 aattggccgc cagttaatgg aacagtgcgc gaaagacatc aagaaagtgt cgctggagct
     3361 gggcggtaac gcgccgttta tcgtctttga cgatgccgac ctcgacaaag ccgtggaagg
     3421 cgcgctggcc tcgaaattcc gcaacgccgg gcaaacctgc gtctgcgcca accgcctgta
     3481 tgtgcaggac ggcgtgtatg accgttttgc cgaaaaattg cagcaggcag tgagcaaact
     3541 gcacatcggc gacgggctgg ataacggcgt caccatcggg ccgctgatcg atgaaaaagc
     3601 ggtagcaaaa gtggaagagc atattgccga tgcgctggag aaaggcgcgc gcgtggtttg
     3661 cggcggtaaa gcgcacgaac gcggcggcaa cttcttccag ccgaccattc tggtggacgt
     3721 tccggccaac gccaaagtgt cgaaagaaga gacgttcggc cccctcgccc cgctgttccg
     3781 ctttaaagat gaagctgatg tgattgcgca agccaatgac accgagtttg gccttgccgc
     3841 ctatttctac gcccgtgatt taagccgcgt cttccgcgtg ggcgaagcgc tggagtacgg
     3901 catcgtcggc atcaataccg gcattatttc caatgaagtg gccccgttcg gcggcatcaa
     3961 agcctcgggt ctgggtcgtg aaggttcgaa gtatggcatc gaagattact tagaaatcaa
     4021 atatatgtgc atcggtcttt aactggagaa tgcgaatgaa cagcaataaa gagttaatgc
     4081 agcgccgcag tcaggcgatt ccccgtggcg ttgggcaaat tcacccgatt ttcgctgacc
     4141 gcgcggaaaa ctgccgggtg tgggacgttg aaggccgtga gtatcttgat ttcgcgggcg
     4201 ggattgcggt gctcaatacc gggcacctgc atccgaaggt ggtggccgcg gtggaagcgc
     4261 agttgaaaaa actgtcgcac acctgcttcc aggtgctggc ttacgagccg tatctggagc
     4321 tgtgcgagat tatgaatcag aaggtgccgg gcgatttcgc caagaaaacg ctgctggtta
     4381 cgaccggttc cgaagcggtg gaaaacgcgg taaaaatcgc ccgcgccgcc accaaacgta
     4441 gcggcaccat cgcttttagc ggcgcgtatc acgggcgcac gcattacacg ctggcgctga
     4501 ccggcaaggt gaatccgtac tctgcgggca tggggctgat gccgggtcat gtttatcgcg
     4561 cgctttatcc ttgcccgctg cacggcataa gcgaggatga cgctatcgcc agcatccacc
     4621 ggatcttcaa aaatgatgcc gcgccggaag atatcgccgc catcgtgatt gagccggttc
     4681 agggcgaagg cggtttctac gcctcgtcgc cagcctttat gcagcgttta cgcgctctgt
     4741 gtgacgagca cgggatcatg ctgattgccg atgaagtgca gagcggcgcg gggcgtaccg
     4801 gcacgctgtt tgcgatggag cagatgggcg ttgcgccgga tcttaccacc tttgcgaaat
     4861 cgatcgcggg cggcttcccg ctggcgggcg tcaccgggcg cgcggaagta atggatgccg
     4921 tcgctccagg cggtctgggc ggcacctatg cgggtaaccc gattgcctgc gtggctgcgc
     4981 tggaagtgtt gaaggtgttt gagcaggaaa atctgctgca aaaagccaac gatctggggc
     5041 agaagttgaa agacggattg ctggcgatag ccgaaaaaca cccggagatc ggcgacgtac
     5101 gcgggctggg ggcgatgatc gccattgagc tgtttgaaga cggcgatcac aacaagccgg
     5161 acgccaaact caccgccgag atcgtggctc gcgcccgcga taaaggcctg attcttctct
     5221 cctgcggccc gtattacaac gtgctgcgca tccttgtacc gctcaccatt gaagacgctc
     5281 agatccgtca gggtctggag atcatcagcc agtgttttga tgaggcgaag cagtagcgcc
     5341 gctcctatgc cggaggcgac gctgcgcgtc ttgtccggcc tacggggatc caggtcggat
     5401 aaggcgttta cgccgcatcc gacaatctgt acgtgaacag gaagaaatct atgttggccg
     5461 ggtaaggcgg agccgctctc cggcaaaaag aatcaataac aattatacgc gtgacccggc
     5521 gcgggaaatg tcggggcgct ctcccaagtg acacactttc gagaggattc aggatggggc
     5581 aatcatcgca accacatgag ttaggcggcg ggctgaagtc acgccacgtc accatgttgt
     5641 ctattgccgg tgttatcggc gcaagtctgt ttgtcggttc cagcgtcgcc atcgccgaag
     5701 cgggcccggc ggtattactg gcctatctgt tcgccgggct actggtggtt atgattatgc
     5761 ggatgttggc ggaaatggcg gttgccacgc ccgataccgg ttcgttttcc acctatgccg
     5821 ataaagccat tggtcgctgg gcgggctata ccatcggctg gttgtactgg tggttttggg
     5881 tactggttat cccgctggaa gccaacatcg ccgccatgat cctgcactca tgggttccag
     5941 gcattcccat ctggttattt tccctcgtca ttaccctcgc cttaactggc agtaacttat
     6001 taagcgttaa aaactacggc gaatttgagt tctggctggc gctgtgcaaa gtcatcgcta
     6061 tcctggcctt tattttcctt ggtgcagtcg caattagcgg tttttacccg tatgccgaag
     6121 tgagcgggat ctcaagattg tgggatagcg gcggctttat gcccaacggt ttcggtgcgg
     6181 tattaagcgc gatgttgatc accatgttct cgtttatggg cgcagaaatt gtcaccattg
     6241 ccgccgcgga atccgacacg ccggaaaaac atattgtccg cgccaccaac tcggttatct
     6301 ggcgtatttc tatcttctat ttatgttcta tttttgtcgt cgtggcatta attccgtgga
     6361 atatgcccgg actaaaagcc gtcggttctt atcgctcggt actggaattg ctcaatattc
     6421 cccatgcgaa attaatcatg gactgcgtga tattactttc cgtaaccagt tgcctgaact
     6481 cggcgctgta taccgcgtca aggatgctct actccttaag tcgtcgcggt gatgctcccg
     6541 cggtaatggg taaaatcaac cgcagtaaaa ccccgtacgt ggcggtgtta ctctccaccg
     6601 gcgcggcatt cttaacggtg gtggtgaact attacgcgcc tgcgaaggta tttaaatttc
     6661 tgatcgacag ctccggcgct atcgccctgc tggtttattt agtcatcgcc gtttcacagt
     6721 tgcggatgcg caaaattctg cgagcagaag gaagcgaaat tcgcttgcga atgtggcttt
     6781 atccgtggct cacctggcta gtcatcggct ttattacctt tgtgttggta gtgatgctat
     6841 tccgtccggc gcaacagtta gaagtgatct ccaccggctt attagcgata gggattatct
     6901 gtaccgtgcc aattatggct cgctggaaaa agctggtatt gtggcaaaaa acacccgttc
     6961 ataatacgcg ctgatcatga tcaggagtca caccatgacc attacgtctc tggatggcta
     7021 tcgctggctg aagaacgata ttattcgcgg taattttcaa ccggatgaaa aattacgaat
     7081 gagtttgctg acatcgcgtt atgcacttgg cgttgggccg ttacgggaag ctctttcgca
     7141 actggtggcg gaacggctgg tcacggtggt gaatcaaaaa gggtatcggg tggcgtctat
     7201 gtcagagcag gagctgctcg atattttcga cgcccgcgcc aatatggaag cgatgttagt
     7261 gagtctggcg attgcccgcg gtggcgatga gtgggaggca gacgttctcg caaaagcgca
     7321 tctgctgagt aagcttgagg cctgtgacgc cagcgagaaa atgcttgatg agtgggatct
     7381 gcgtcatcag gcgtttcata cggcaattgt ggcgggctgt ggttctcact atttgctgca
     7441 aatgcgtgaa cggttgtttg atctggcggc gcgttatcga tttatctggc tgcggcgaac
     7501 ggtgctttcg gtggaaatgc tggaggataa acacgatcag caccagaccc tgactgcggc
     7561 ggtactggcg cgagataccg cgcgcgccag tgagttaatg cgccagcatt tactgacgcc
     7621 aattcccatt atccagcagg cgatggctgg caattaacta ctcttccgga atacgcaaca
     7681 cttgccccgg ataaatttta tccgggcttt ttagcatcgg tttattcgct tcgaagattt
     7741 tattgtacag attagcgtta ccgtagacct gtttggaaat ggcactcaga gtgtcgccag
     7801 acttaacggt ataaaactgg ctggcagtgg ctggtgtcgc cgttttcacc tgatcatcga
     7861 cactggcaat accggaaata ttccccaccg caacaaggat tttctccttc gcctcctgac
     7921 tcaggccgtc accagtgacc gtcgctttgc cgtcggcaat ttgaatattc actttatcgg
     7981 catccggtat accggttttg ttcagatgct cctgcacctt cttcgcctga tcgtctttat
     8041 cgtgctgacc tgtaaccgcg tcccagagtt tttctccggc atctttcaca aaattgaaca
     8101 gacccatagc tacctcattc gttaacggaa acactcagaa agtgtagcag aggaacgcgg
     8161 cgcgttaacg ccgcggggat gagcacaggt ttaatcgcgg gtttgcaccc agaacgcgtg
     8221 aatcaaaccg gggatatacc caagcagtgt caacagaata ttaataatga acgcccaacc
     8281 gaacccttta ccgagcagca cgccgagcgg cggcagaatg atggtgatga cgattctcca
     8341 gaaacccata tgtactc
//
LOCUS       DAPHKZ010000173         8239 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.174, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000173 DAPHKZ010000000
VERSION     DAPHKZ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8239
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.174"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..573)
                     /locus_tag="RH288_004202"
     CDS             complement(<1..573)
                     /locus_tag="RH288_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4033191.1"
                     /translation="MSKKLGFALSGLMLAMVAGTASADMDGGQLNISGLVVDNTCETR
                     VDGGNKDGLILLQTATVGEIDAGVLNDTVGAKAKPFSITVDCSKANPNPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINNPSDGVNIALHNIDGSTIKQVQINNPGDVYTKALDATTKS
                     AVYDFKASYVRAVADQTATAGYVKTNTAYTI"
     gene            complement(943..1422)
                     /gene="folK"
                     /locus_tag="RH288_004203"
     CDS             complement(943..1422)
                     /gene="folK"
                     /locus_tag="RH288_004203"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDV4033192.1"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTP
                     PLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHTRAFDKLNKW"
     gene            complement(1419..2837)
                     /gene="pcnB"
                     /locus_tag="RH288_004204"
     CDS             complement(1419..2837)
                     /gene="pcnB"
                     /locus_tag="RH288_004204"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HDV4033193.1"
                     /translation="MTLPRCTIFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQH
                     AISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEY
                     HLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLL
                     ETAQKIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLLEHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDE
                     EPSPRRRTRRPRKRAPRREGTA"
     gene            complement(2876..3802)
                     /gene="gluQRS"
                     /locus_tag="RH288_004205"
     CDS             complement(2876..3802)
                     /gene="gluQRS"
                     /locus_tag="RH288_004205"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001432381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HDV4033194.1"
                     /translation="MLPPYFLFKEMTDTQYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHDAYREALAWL
                     HEQGLSYYCTCTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFS
                     VEQILQSAVKNWRLTAVPESAIVNSTFSNASC"
     gene            complement(3839..4294)
                     /gene="dksA"
                     /locus_tag="RH288_004206"
     CDS             complement(3839..4294)
                     /gene="dksA"
                     /locus_tag="RH288_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HDV4033195.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(4472..5176)
                     /gene="sfsA"
                     /locus_tag="RH288_004207"
     CDS             complement(4472..5176)
                     /gene="sfsA"
                     /locus_tag="RH288_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDV4033196.1"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     ISAEGMALKKSLPVTL"
     gene            complement(5191..5721)
                     /gene="thpR"
                     /locus_tag="RH288_004208"
     CDS             complement(5191..5721)
                     /gene="thpR"
                     /locus_tag="RH288_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HDV4033197.1"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     gene            5795..8224
                     /gene="hrpB"
                     /locus_tag="RH288_004209"
     CDS             5795..8224
                     /gene="hrpB"
                     /locus_tag="RH288_004209"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HDV4033198.1"
                     /translation="MSSLPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDDAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGISLH
                     LIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPVVNLLAAKRL
                     LQMLGALEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDG
                     RYQLANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALLVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLAALETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
BASE COUNT         1955 a         2069 c         2235 g         1980 t
ORIGIN      
        1 aatggtgtat gcagtgttag tttttacata accagcagtt gctgtttggt ctgcgacggc
       61 acgaacgtaa gacgctttaa aatcataaac agcagatttt gtcgttgcat ccagggcttt
      121 agtatacaca tcgccagggt tgttaatttg aacctgtttg atagtggaac catcaatatt
      181 gtgtagagcg atattaacgc cgtcagatgg gttgttaata gacatgtcgt tgttcaaagt
      241 ccctttgctg ttaccaaaga aaacagaacc gaaggtcatt ttagccgtgc tacctggatt
      301 cggatttgct ttgctgcagt caacggtgat gctgaaaggt ttagctttag cgccaacggt
      361 gtcattcagt acgccagcat cgatttcacc aacggttgcg gtttgcagca ggatcagacc
      421 atccttgtta ccgccgtcaa cgcgggtttc acaggtgtta tcaacaacca gaccactgat
      481 atttaactga ccgccgtcca tatcagcaga agcagtacct gcaaccatcg ccagcataag
      541 accagacagg gcaaaaccta attttttaga cataaaaatc ctttaataaa attccattag
      601 tcagactaca tgtttgaaga atgactattc atgacacaaa taggagaaac aaatgttaga
      661 tattaatgag caatgatatt tgttacccaa atttacaacc attgttcatt aggtcgccta
      721 ttgtgcactt tagaagcttt tgaacaaatt aaatttactt aattcaaaat taagtaaaaa
      781 taagttcaca agtgcaattg gttagggtat ggagatggga ttgatattta tttataggaa
      841 gttatattat ttccgcaaag agatgtttaa actaaaatcg taattaagga aagagatgag
      901 atatgatttt cagaaaatat ttatattcgc aatataaata aattaccatt tgtttaattt
      961 gtcaaatgct cttgtatgta agatttgacg caacatctcc ccatcaggaa acaccaactc
     1021 cggcgcgatt tcaaacagcg gccacagcat aaatccacga ttcttcatat cgtagtgcgg
     1081 aacggtcagg cgttcagtat ttatcacttc attaccaaac agcatgatgt cgagatccag
     1141 cgtgcgtggt ccccagcgtt cagctttgcg gacgcgacct tgctgcaatt caatacgctg
     1201 tgtgtgattg agtagctctt caggtgcaag agaggtttcc agcgccacgg ctgcgtttaa
     1261 gtaatcgggt tgatcttgcg gccccagcgg tggggtgcgg taaaacgaag aaacggtaag
     1321 aatgtggctt tcagggatat cgcctaatgc tttcagggca gcattgacct gctccagcgg
     1381 agaggccaga ttgctgccta tggcaatata cgccactgtc atgcggtacc ctcacgacgt
     1441 ggtgcgcgtt tgcgtggacg acgagtacga cgacgcggtg acggttcttc atccagctcg
     1501 ttgagcatcc ctttttggtc tggtggcgcg gaaacctgga actcacccca ccatttcacc
     1561 agacgctgca gttcagcgtt acgctcaact tcagctcgca aggccaacag gtcataagcc
     1621 gcacggaact taggatgctc cagcagtttc catgcgcgtt taccctgacg acgggacata
     1681 cgcaactgca actgccagat atcgcgggtt aatgtcgtca gacgtttcgg gattgccagt
     1741 gaacggcagg cttcgtccag cacgtcgttc atcgccagcg cgaaagcgtc gtgataggtc
     1801 aggccgcttt cctgggcgat cttctgtgcc gtctccagca gtgggtacca gaacatggcg
     1861 gcaaacagga acgccgggtt cacgcgcata tcgttatgga tacgcgtatc ggtattcttc
     1921 agcacctgtt caatgatccg ctccatcggg ctgtcgccat tttccgtgaa gtagcgggta
     1981 atggtcggga acagcggctg gaacagatga tattcacaca acagcttata ggtttcgtaa
     2041 ccgtagcccg cttgtagcag tttaagcgat tcttcaaaca ggcgtgccgg tgggatatcg
     2101 ttcagcaggg tagcgaggcg agggatcggt tctgcggttt ccgggctgat gcgcataccc
     2161 aatttggcgg caaaacgtac cgcgcgcagc atacgtaccg gatcttcacg gtagcgcgtt
     2221 tccgggttac caatcagacg gataacgccg tccttcagat ccttcatgcc gccaacgtaa
     2281 tcacggacgg taaaatccgc tacgctgtaa tacaggctgt tgatagtgaa atcgcggcgc
     2341 tgggcgtctt cttcgatgga gccgaaaatg ttgtcgcgca gcaacatgcc gttttgcccg
     2401 cgttgggagg tcgtgcggtc gctgacgtta ccttcgtggt gtccacggaa ggtcgcaact
     2461 tcgataatct ccgggccaaa cattacatga gccagacgga aacggcgacc caccaggcgg
     2521 cagttacgga acagtttgcg cacctgctca ggcgtggcgt tagtggttac gtcaaaatct
     2581 ttcggctttt tgccaagtaa caggtcgcgc acgccgccgc caaccagcca ggcttcgtat
     2641 cccgctttat tgagcctgta cattaccttc agggcatttt cactgatatc tttgcgggaa
     2701 atagcatgct gctcacgcgg gatcaccgtc acctgtggac gggcgactgc ctgttcagcc
     2761 tcgctttcct cgcggcttag caccttgcgg caaaaattag cgactcgggt aaaaatagta
     2821 cacctcggta gtgtcaaaca tcattcagga caaaaaaata gcggctaatc atagctcagc
     2881 atgacgcatt tgagaatgtt gaatttacaa ttgccgactc gggcacggcg gtaagccgcc
     2941 agtttttgac ggctgactga aggatttgct cgacgctgaa atcctgccag tgtgcttctg
     3001 cctgctgccc cagaaattga agtgccgcga ttagtaccgg gcgtggatcg cctttcggca
     3061 acgcaggcgc atgattctgc ttggaaagtt tagcgccttg tggattaagc gccagcggca
     3121 gatgaatgta atctggcact ttccagccaa aaagctggta cagcgagatt tgccttactg
     3181 ttggttcaat cagatcagcc ccacgcacta tttctgtaac gccctggaaa tgatcatcaa
     3241 ccacaacagc caggttgtag gcgaacaacc catcacggcg atgaatgata aaatcttccc
     3301 gtgccagttt ttcgtcggcg tgaataatgc cgcgcagctg gtcagtaaat tgcgtgaccg
     3361 gatgctgctg gcggatacgc actgcggcgt tgtctggtcc atgatgcaac acccggcaat
     3421 gaccgtcgta aataccgcca atgctttgaa tacgcgcacg cgtacaggtg cagtaataac
     3481 ttagtccttg ttcatgtaac caggcgagtg cttcacgata ggcgtcgtga cgttgcgatt
     3541 gccagagaac atcgccgtcc cagtgcagac cgtaatgttc cagctggcgc aggatagttt
     3601 ctgcggcacc gggaacttca cgaggcgggt cgatatcttc tatgcgtacc agccagcgac
     3661 cttgccgggc gcgagcctgc aaatagctgc cgagcgcggc gatcagagag ccaaaatgaa
     3721 gctcgccgga aggagagggg gcgaagcggc caatatactg tgtgtctgtc atctctttga
     3781 acaaaaaata aggcgggagc atttcccgcc tgtggtaaac gtgatggaac ggctgtaatt
     3841 agccagccat ctgtttttcg cgaatttcag ccagcgtttt gcagtcgatg cacagatcgg
     3901 ctgtcgggcg cgcttccaga cggcgaatac caatttcaac accgcaggat tcgcagtagc
     3961 cgaaatcttc gtcttccact tttttcagcg tcttctcgat ctttttgatc agcttacgct
     4021 cgcgatcgcg gttacgcagt tcgaggctga actcttcttc ctgggctgca cggtctaccg
     4081 ggtccgggaa gttggctgct tcatcctgca tatgtgtaac ggtgcgatcg acttcatccc
     4141 tgagttgatt acgccatgct tccagaatac gacggaagtg cgccagctgg gcttcattca
     4201 tatactcttc gcccggcttc tcctgatatg gttccacccc agcgatggcg agaatactca
     4261 gggacgatgt tttacggttt tgcccttctt gcatgttgct tctccttaac acgcactatc
     4321 gatccccatg ttcgggggaa aaatgaggcc gctataaata gcagatgctt ttccggatag
     4381 caattatcta aacgtaacac ttgacaactg tgtgaggaaa agcgtatttg cgcacgcgac
     4441 cagaatgtaa attaaccagt tacttacttt actacaatgt aaccggcagt gattttttaa
     4501 gagccatgcc ttcagcagaa atttccgctt tgtaagccag aatttctacc cccctctgtt
     4561 gagcttctga caatagttgc gcgtatttct catcgatgtg gcgcgcgggt gaaaaccgtg
     4621 taatggctga atgcagcacg gcgaaaaaga taaccgcacg ctggccttca gccgctacgc
     4681 tcatcaactc ccgaaggtgt ttctgacctc gttcagtgac cgcatcggga aaatatccct
     4741 gttcgttctc cgctaacgta accgatttca cttcaatata gcagtctgga cgcgaatccg
     4801 cctgcaacat aaagtcaata cggctgcgtt ctgcgccgta ttttacttcg cttttcagcg
     4861 agctatagcc tgacagttct gaaattgatt cattaaggat agcctctttc gtcaacctgt
     4921 tagcccaaag cgtgttgacg caaataaatg cgccgctctg gctttgagtt aattcccagg
     4981 tgtgtgggta tttccgtttg gtgttgtctg aagtcgaata ccagacggta tcgccaggcg
     5041 ttgcacaacc ggtcatcgca cccgtattcg ggcagtgtag cgttaattcg cgaccatcgg
     5101 gtgtgatcac atcggctaaa aaacgtttgt aacgctgaat tagcgtcgcg cgctgtagag
     5161 ggggagaaaa ttccattgcg acaatccttg ttattgcgtt agcgcccagc gttttagcgg
     5221 cgtgtagcgt gtgcgtccac gggcaaacga ggaggcgtaa agggtgaact ccgtcaccgc
     5281 atacgaccag ttaaaacctg gcggcgggat tgtcaccgcc tcgctggcgt cgcgcaataa
     5341 ggtaatatgt ggatgaaacg gacgattgct ttgaaaacaa ccgctgcggg cagcctgtga
     5401 acggagcata ttcgccagct ggattaagcc gcgtggcggc tgacgcatcc ctaaccacac
     5461 cacacgcgaa cgcagccatt gtccggcgtc atcaagcgtg agtgtgaaac caggttgacg
     5521 aatccgtccg gctaaaagag aaagcgcctt ctctttctcg gcgctcactt cgcctaaaaa
     5581 tgccagagtc agatgcaaat tatcggcggc gaccggacgt cccgcctcag gtgggaagtg
     5641 tgtggcgcgc caatggataa tctgttcgcg gatttctgca ggtaagtcga tagcaaagaa
     5701 cagacgttgc ggttcagaca tgtgaggcac tcggttatga attaccgcga tgctacaatg
     5761 tggcgcgaag aatgttaacc ctctggagcg ttttgtgtcg tcgttgcccg ttgctgccgt
     5821 cttacctgaa ttacttaccg ctctcgattg tgcgccgcag gtattattaa gtgcgccgac
     5881 cggggccggg aaatcaacct ggctgccgct gcaactgctg gcgcatcccg gcattaacgg
     5941 gaaaattatc ctgctggagc cgcgtcgtct ggcggcgcgt aacgtcgcgc aacggctggc
     6001 ggagctgctt aacgaaaagc caggcgatac cgttggctac cggatgcgtg cgcaaaactg
     6061 cgtcgggccg aatacccgcc tggaagtggt taccgaaggc gtgctgacgc gcatgatcca
     6121 gcgtgacccg gaactgagcg gtgttggact ggtgatcctt gatgaatttc atgagcgcag
     6181 cttgcaggcg gatttggcgt tggcgctgtt actcgatgtg caacaaggtc tgcgtgatga
     6241 ccttaaactg ctgattatgt cggctaccct ggacaacgac cgcttgcagc aaatgctgcc
     6301 agaagcgcct gtcgtcatct cagaagggcg ctcgtttccg gttgaacgcc gttatttacc
     6361 gctgcccgcg catcagcgtt ttgacgatgc cgttgcggta gccaccgctg aaatgctgcg
     6421 tcaggaaagc ggatcattac tgttattttt acctggcgtc ggagaaattc agcgtgtgca
     6481 ggaacaactg gcttcgcgca tcggcagtga tgtattgctc tgcccgctgt atggcgcgtt
     6541 gtcgctgaac gatcagcgaa aagcgatcct cccggcaccg caagggatgc gcaaagtggt
     6601 gctggcgacc aatattgctg aaaccagttt aaccattgaa ggtattcgtc tggtggtgga
     6661 ttgtgcccag gagcgtgtgg cgcgttttga tccgcgcacg gggcttacgc gactgattac
     6721 tcaacgcgtt agccaggcat ccatgacgca gcgtgccggg cgcgccgggc gtctggagcc
     6781 gggtatcagc ctgcatttaa tcgccaaaga acaagcagaa cgcgccgcgg cgcaaagtga
     6841 accggagatc ttacaaagcg atctttccgg tttgctgatg gaattactgc aatggggatg
     6901 cagcgatccg gcgcagatga gctggctgga tcaaccgcca gtagtgaatc tactggccgc
     6961 gaaacgtctg ttacaaatgc tgggggcact ggagggtgaa cggcttagtg cgcaagggca
     7021 aaaaatggca gcgctgggta acgatccgcg tttagcggca atgctggtta gcgcgaagaa
     7081 cgacgacgaa gctgctaccg cggcaaaaat tgccgccatt ctcgaagagc cgccacggat
     7141 gggcaatagt gacctgggcg tggcgttttc gcgcaatcaa ccagcctggc agcaacgtag
     7201 tcagcaactg ttaaaacgct taaacgtacg tggcggtgag gcagacagtt cgcttatcgc
     7261 gccgctactt gccggggcgt ttgccgatcg cattgctcgt cgccgtgggc aagatggacg
     7321 ctatcaactg gcaaacggca tgggagcgat gctcgatgcc aacgacgcgc taagccgcca
     7381 cgaatggttg atcgcaccgt tattattgca gggcagcgcc tcgccggatg cgcggatttt
     7441 actggcgctg ctggtcgata ttgatgagtt agtacaacgc tgcccgcagc tggtacagca
     7501 gtctgacact gtggagtggg atgacgcgca aggtacgctg aaagcctggc gtcggctaca
     7561 aatcggtcag ttgacggtga aagtgcagcc gctggcgaaa ccgtcagaag acgagttgca
     7621 tcaggcgatg cttaatggca tccgtgataa aggtttaagc gtgctcaact ggacggcgga
     7681 agcggaacag ctacgcttgc gtttgttatg cgccgcaaag tggttgccgg aatatgactg
     7741 gccagcggtt gatgatgaaa gtttattggc agcgctggaa acgtggctgc tgccacatat
     7801 gactggcgta cattcactac gcggcctgaa atcactcgac atttatcagg cactacgcgg
     7861 attacttgat tggggaatgc agcaacgtct ggatagtgaa ttgcctgcgc attacactgt
     7921 gccgacggga agccggatcg ccattcgtta tcatgaagat aacccgcccg cgctggcggt
     7981 gagaatgcaa gagatgtttg gcgaggccac caatccgacg atcgcccagg ggcgcgtgcc
     8041 gctggtgctg gagttgcttt cacctgccca aaggccatta caaatcacac gagatttgag
     8101 cgccttctgg aaaggagcgt accgtgaggt gcaaaaagag atgaaagggc gttatcccaa
     8161 acatgtctgg ccggacgacc cggcaaatac tgcaccgacg cgacggacga aaaagtattc
     8221 gtaaggttgg ttttctccc
//
LOCUS       DAPHKZ010000174         8116 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.175, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000174 DAPHKZ010000000
VERSION     DAPHKZ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8116
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.175"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(39..728)
                     /locus_tag="RH288_004210"
     CDS             complement(39..728)
                     /locus_tag="RH288_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDV4033199.1"
                     /translation="MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADS
                     WFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSK
                     EGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
                     DDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDT
                     GCEEFEKLTNG"
     gene            complement(822..2969)
                     /gene="fdhF"
                     /locus_tag="RH288_004211"
     CDS             complement(822..2969)
                     /gene="fdhF"
                     /locus_tag="RH288_004211"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(2550..2552),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDV4033200.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSAS
                     EIRQAARMYAQAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRAAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGE
                     HEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLREAALA"
     gene            complement(3167..4633)
                     /gene="mdtP"
                     /locus_tag="RH288_004212"
     CDS             complement(3167..4633)
                     /gene="mdtP"
                     /locus_tag="RH288_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdtP"
                     /protein_id="HDV4033201.1"
                     /translation="MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKL
                     ADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDA
                     GSQLQVAALGMLNRQRVSANGFLSPYSMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
                     HRSAVAAAIGAHNAALAETAAVELSLATGVAQLYYSMQASYQMLDLLEQTHDVIDYAV
                     KAHQSKVAHGLEAQVPFHGARAQILAVDKQIVAVKGQITETRESLRALIGAGASDMPE
                     IRPVALPQVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAF
                     FGLDSIHLHTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVL
                     NAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPV
                     LAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAGPVVEKK"
     gene            complement(4630..6681)
                     /gene="mdtO"
                     /locus_tag="RH288_004213"
     CDS             complement(4630..6681)
                     /gene="mdtO"
                     /locus_tag="RH288_004213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter permease subunit
                     MdtO"
                     /protein_id="HDV4033202.1"
                     /translation="MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVI
                     LISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEP
                     LIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
                     VVGLYPTLLMTLIGVLWFPSRAISQMHQALNDRLDDAISHLTDSLAPLPETRIEREAL
                     ALQKLNVFCLADDANWRTQNAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKL
                     ASEINKLQHAVAEGQCWQSDWRISESEAMAARECNLENICQTLLQLGQMDPNTPPTPA
                     AKPPSMAADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVG
                     SSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERS
                     SYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEART
                     LPQKLAGTLGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVALERQLD
                     SEERALLIERSQTVIRQGRDLLHAWDATWNSAQALDNALQPDRAGQFADALEKYAAGL
                     ATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQVQGAT
                     Q"
     gene            complement(6681..7712)
                     /gene="mdtN"
                     /locus_tag="RH288_004214"
     CDS             complement(6681..7712)
                     /gene="mdtN"
                     /locus_tag="RH288_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter periplasmic adaptor
                     subunit MdtN"
                     /protein_id="HDV4033203.1"
                     /translation="MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYA
                     SADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQI
                     MLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
                     QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGR
                     VISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKT
                     FEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGA
                     SAVANLEPQ"
     gene            complement(7731..8006)
                     /locus_tag="RH288_004215"
     CDS             complement(7731..8006)
                     /locus_tag="RH288_004215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033204.1"
                     /translation="MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWF
                     FCAIASLILTLITRRVIQRANINLAFVGIIYTALFALYAMLFWLAFF"
BASE COUNT         1861 a         2203 c         2146 g         1906 t
ORIGIN      
        1 gcctgatgcg acgcttgccg cgtcttatca ggcctatctt aaccgttggt taatttttca
       61 aactcttcac acccggtatc aaacccttcc atacagctca ggttcaacca gtgcagcgcc
      121 ttttgcttgt tcttctcgat aaaaccttct tcaccgttta agaacatcat tcccgcccag
      181 tactcggaat aaccggttcg ggaaattgca gagctgcgtt tgaaatacca ggttgccttg
      241 tcatcgtcgg ccttaatgcc cacgccgttg gcgtaaatca aaccaagcag catttgggca
      301 tcgacggcag agtcgttctc cagatcttcc gaggcgtttt ctaacagcga aattgccttt
      361 ggataatccg gtttacccgc ttgagtattt accagaatat gcgccagcgt tacttcacct
      421 tctttactgc ccgcttgcgc cgctttctct gcaagaactt ttgcttgtgg atagtccaga
      481 ctgaccggat tggtgatttt gatctgcgcc agcagcgcgc aggcatcagc atcaccgctg
      541 tcggcggctt tctgtgccca atattcggct ttgctcaaat cgccggagct aaaccagctg
      601 tcggcaagaa aatattgtgc gcgtcggtcc ccggcctctg ctgcctttaa atactggctg
      661 ccaggctcgg agtcgttggc gtgggcaaag aatgtcaaaa acaacatcaa tgcgataatt
      721 tttttcattt tgataatacg attgggtagg gagtaaccag tataaagagt tcgaatggat
      781 aaaaaaacag cctctgaaag gaggctgtag aaaggacggt attacgccag tgccgcttcg
      841 cgcaggcgag ttttcaactt gttgtactcg tcaatcacgt actgctcggc ggcgcgctga
      901 tcggcgatcg gctcgacgcg cacggcgcag tatttgtatt ccggcgtttt cgtaatcggg
      961 cttaagtttt cggtaaccag ctcgttacag gcaccaatcc accactggta ggtcatgtaa
     1021 atcgcccctt tgttcggacg atcgctgacc tgcgcacggg tgataatttt gcctttacgc
     1081 gagtgcaccc aaaccaatgc ctcatcttca atacccagac gtttggcgtc ttcggtattg
     1141 atttgtgcgt agccaggttc atcagccagc gccgccagtg ccgcacagtt accggtcatc
     1201 gaacggcaag agtagtgacc aacttcacgc accgttgaca gtaccatcgg gtactcgtcg
     1261 gtgagtttgt cgattggcgc tacccagtcg caggtgaaga actgcgccag accgttcggg
     1321 gtatcaaact tctctttaaa cagataagaa gtcccctgat cggcatctga agtatcgcgg
     1381 caaggccact gaatgaagcc cagttcgccc attttctcgt aagtcgcacc gtagaaatcc
     1441 gggcacagat gacgcaactc atcccagatc tcctgggtgt tgttgtagtg catcggataa
     1501 cccatacggg tggcgatttc actgatgatt tgccagtccg ttttcagatc ccatttcggt
     1561 tcaaccgcct tgaagaaacg ctggaagcca cggtcagccg cagtaaacac gccttcatgc
     1621 tcgccccacg acgttgacgg taaaataaca tccgccgccg acgcggtttt ggtcataaag
     1681 atgtcctgaa cgataaccag ttccagatct tcaaaggctt tacgtactgc cgacagctcc
     1741 gcgtcagttt gcagcggatc ttcgcccata atgtacgcgg cacgcacttc gccatgcgct
     1801 gcgcggtgcg gtagctcgct gatgcgatag ccggtatgcg ctggcaggct ttccacgccc
     1861 caggctttgg cgaatttctc gcggttagcc ggatctttca cgtactggta tcccggatac
     1921 gtatccggca gcgcgcccat atcgcaggca ccctgtacgt tgttctgacc acgaaccggg
     1981 ttaacacccg catgtggctt accgaggtta ccggtcagca tcgcgaggct ggtcagagaa
     2041 cgcacggttt ccacgccctg gtagaactgg gttacaccca tgccccacag gatggcggcg
     2101 cttttcgcct gggcatacat ccgtgccgcc tgacgaatct cactggcgct gacgccggtg
     2161 atatcttcaa ccgactccgg cgtgtagcct tcaacgattt tacgatactc ttcaaagcct
     2221 tctgtacggg aagcgacgaa tgctttgtcg tacaaatttt cttcaataat gacatggccc
     2281 atcgcattca acagcgcgat gttcgagccg tttttcagtg caatgtgcat gtcagcaatg
     2341 cgcgcggttt caattttgcg cggatcgcag acgataattt tcgccccgtt acgtttagcg
     2401 ttaattacgt gattcgctac gattgggtgg gaatccgccg ggttgtaccc gaaaacgaac
     2461 actaaatcgg tattatcaat ttcgttaata gcattgctca ttgcgccatt accgaccgat
     2521 tggtgcagac ctgcaaccga tgggccgtgt cagacacgag cgcagcagtc aacgttattg
     2581 gtaccaataa cggcgcgcgc aaatttttgc attacatagt tggtttcgtt acccgtacca
     2641 cgcgaggagc cggtcgtctg gatggcatcc ggaccgtact tctctttgat ggcgctcagg
     2701 cgctcggcaa cgtaattcag tgcctcatcc caggaaacag gttcgagttt gccgccacgc
     2761 tggcgacgga tcatgggggt tttcaggcgc ggggtcagga tctgggtatc gttaatgaag
     2821 tcccagccat aataaccctt cagacacagg gtaccctggt tggttttccc ctgcgctgcc
     2881 tccgcccgga cgattttgcc gttatcgacg accaggttga ttttgcaacc tgatgcgcaa
     2941 taggggcaaa ccgtgacgac ttttttcatc ggtctcgctc cagttaatca aatcacgcat
     3001 acgcgctctc gactacagta tgcatctttt atgccacatt ttatgtgggg tcattccctg
     3061 agattacggg cactatttat tcaaaactct gacgaaaaac aggctgtcgt cagttttgac
     3121 gtgacgaaac gaaataccgc gtgacagcca tcacgcggca gacattttat tttttctcga
     3181 cgacgggacc tgcctgatac ccgccgccca gcgatttcat caactgaatg ctttggatca
     3241 cccggcggct gtccagcatc agtaatgaca tctcttcggc aagcactggc aaccgggctt
     3301 cggtggcctg taagcggctg gttaagccgc gctgataggc ggcctcggca gcgcgctggg
     3361 taaagcgcgt ggcttccacg cgttcagcct gcatttctcg ctcgtcgttg agcgtttgca
     3421 gacgcgtgcc gttgacggca acgtcacgca ccgcgttcag tactgactgg ttgtaacgtt
     3481 caatcatcat gttgctggcg gcgcgcgtgc cttcgagatt ggcattcaac cgtccaccgt
     3541 caaacagcgg caatttcaga cccgggatga agttgaactg gcgactggtt tttttgaata
     3601 aggtatgcag atggatggag tccagaccga aaaacgcttt gatatcaaag ctcggataga
     3661 acaacgcccg cgcggaatcc acctgatcta atgacgcctg aacataccag cgcatggctt
     3721 gcagatccgg gcgtctggcg agcaactcat aagagagtgt cgccggaatg ccggtctgga
     3781 cttgcggtaa tgccaccggt ctgatctccg gcatatcgct ggctcccgcg ccaatcaatg
     3841 cacgcagaga ttctcgcgtt tcggtgattt gccctttgac ggcaacaatt tgtttatcga
     3901 ccgccagaat ctgtgcccgc gcgccgtgga aaggcacttg cgcttccaga ccgtgcgcca
     3961 ctttactctg gtgcgctttc accgcgtaat caatcacatc gtgagtttgt tctaacagat
     4021 cgagcatctg atagctggcc tgcatactgt aataaagctg cgctacgccc gtggccagcg
     4081 atagctctac tgctgcggtt tctgccagcg cggcattatg cgcgccaatg gcggcggcaa
     4141 ccgctgagcg atgcacaccc cacaaatcaa gatccagtcc ggcaaacaaa cctactgtgg
     4201 cttccgtata gtacggcccg tccataccca gtgctggcgc atccattgaa taagggctta
     4261 aaaagccgtt cgccgagaca cgttggcggt tgagcatccc taacgctgcg acctgtaatt
     4321 gtgaaccggc atctaacaaa tcggcctggg actgcgcttt ttcttcccgc agtttcgctt
     4381 cggcgagggt gtgtgaacca cttagcgtcc gttggatcag cgcatccagc tgcgggtcat
     4441 tgagttgttt ccaccactgc gcctgcggcc agccggagct ggcaagatga atatcgtcgg
     4501 ccagtttgat ttgttccggt ttgagctgtt gatgaggtgc agaatcctta cgtaccaggg
     4561 cacagccgga aatcagcgtc gtgctgccga gaatgctgca caacagcaga cgtgaaagtt
     4621 gacgattgat cattgcgtgg ctccttgtac ctgttccgtg gcgggcgtta atgccggggc
     4681 tgtccagtct ggcaagcggg cgaaaagctg gcagacgtgt tgctcctgtt ttaataaggt
     4741 gggcaggatg gcctgagagg cgggtgtctc ttcaagcgtt atttgaggag aacggctgag
     4801 tgcggttgcc agaccggcag cgtatttctc cagggcgtcg gcaaactgac ctgctctgtc
     4861 cggctgtagt gcgttatcca gcgcctgcgc cgagttccag gtggcatccc aggcgtgaag
     4921 aagatcgcgg ccctgacgaa taaccgtttg cgaacgttca atcagtaatg cgcgttcttc
     4981 gctgtccagt tgacgctcca gcgccacgcg ttggcacatc tcttcacagg cattaaacgc
     5041 cgcatgcaga ccgatacgaa tttgcagata agtgcgcaga gccgtgactt cctgctggcg
     5101 tgggatccgc attactttac ttaacatacc cagcgtgcca gccagttttt gcggcagtgt
     5161 gcgcgcttca ctttcaggcc agacaaaggt gtaaatcacc gcggacacca cggtaccaat
     5221 gatgataccc agggcgcgat cgcgaatttc caccaggtcg tacactgggc caaaaacgtt
     5281 ttcgagcgtg gcgagcgcga aggtgaccac catctgtgtg ccgatataag aagagcgttc
     5341 agagctggtg gcaatccatg cgcccaacag gaaaatcggt gccagcacaa acagcaattc
     5401 gacaatattg tccagccagg gcatgaccag tagcgtgaat aacagcgcca gaatcgcgcc
     5461 gcaaaaggcc ccgccaaaac gcagcaccat cttctggtac gacgaaccga catttgggtt
     5521 agcgacgatc acgcatgtca gcatacaggt gtgaatgcct tcccagtcca cgccgctgta
     5581 aaaggtgtaa cagatcaaac aggcgagcag cgtttttacc gcgtagcgca tatagtctgg
     5641 attggtaaaa gcatcggcgg ccattgatgg cggtttggct gcgggcgttg gcggcgtatt
     5701 cgggtccatc tgacccagtt gtaacaacgt ctggcagata ttctccaggt tacattcccg
     5761 tgccgccatc gcttcacttt cactgatccg ccagtcgctt tgccagcact gaccttcagc
     5821 aacggcatgc tgcagcttgt tgatttctga agctaatttt tgtcggaatt caataattgc
     5881 ctgagaatca gcaaaagagg tgggatcgta gcgattcagc gtcgagtaaa tgtaggttac
     5941 cgttgccacg cagctttgcc accatgcgtt ttgagttcgc cagttggcat cgtccgcgag
     6001 gcaaaagaca ttgagttttt gtagcgccag cgcctctctt tcaatccgcg tttcgggtag
     6061 cggtgcgagg ctgtctgtca ggtgactaat ggcatcatca agccgatcat taagcgcctg
     6121 atgcatttgc gaaatggcac gactgggaaa ccacagcacg ccgattaacg tcatcagcaa
     6181 ggttggatag aggccaacaa cgatacacca cagcgttaag cgcacgacca cttccggata
     6241 gtcgagcatg gcggggaagg tttgcccgta aatagcgaca atggcgacgg cgaaaaagac
     6301 cagccccaag cgatgggtgc gcatcaaaaa catgcagccc atcaggatcg gtccggcgat
     6361 gatcaatcgg atcaacggtt cgccgtatga ccatttgtag atcaaaaaca ggctgccgat
     6421 ctccagcacc gtggcaacca caaacaagat cgcgacaaat ttggtgtaaa acgcgttcga
     6481 ctgaataccg taaaacagca ctgccagcga taacgccaca aaagggatct caaaggtcat
     6541 cgagatcaga atcaccagca ggcagcctac ccagagttgc acggtctgcg gcacgcgacc
     6601 tggtcgccgc tcgcttaact cttcatgaaa gaacgccagc agcctgacca ccggtaatgg
     6661 cagggagttg agcgcgctca ttattgcggc tcaagattag cgactgccga agcgccgatg
     6721 cggaacattt ccgggtcagg tttatcgacc atgattttga ccggaaaacg ctgggcaacg
     6781 cggacccagt taatagaacg agacactttc ggcaggccgc ccagcaccag gccgccgtca
     6841 tccggtagca cgccgtagcc aatcgaatcc actttaccct cgaaggtttt gccgctgtca
     6901 ctcatcaggc gaatcgttgc gggtgtacct gagcgaatat ttttcagatc ggtttcgcgg
     6961 aagttggcga tcacatacca gtgacgagtg tcgattaggg taaaaatagg gcgcatggca
     7021 gaagcaaatt gcccgacgga ggttttgagg gaaatgaccc ggccatcaaa cggcgcgcga
     7081 acggtcgcca tttccagatg cagtttggtc agggcaatat ccgcttcgac cgccgcacgc
     7141 tgggcaacta atgcatccac gccgctgacg gcgctggcgg ctgactgcgc ctgtaacaat
     7201 acggcattaa gatccgcttc tgcggcgcgc tgcgccgttc ttgcacggtc aacatcttcc
     7261 gctgagacaa aaccttcttt cagtaatggc tcggtgcggc gtaatgtatc tgtggcctgt
     7321 ttcgcggcgg cacgggcttt ttctaccgtg gcattaaccg agtcggcacc aaactgttgc
     7381 gcgtcaacgc tacgctgggt gagcataatt tgcttatcca gcgccgcgag ggaggcttca
     7441 gctttcgcca gattggcttc gtacgggcgc gggtcgatgc ggaacagcaa atcgccctgt
     7501 ttgactgcct ggttgtcggt gaccgccagt tctacaatgc ggccgctgac ttccggtacc
     7561 acatcaatgg tatctgctga cgcgtaagcg tcattagttg atggcgcact gtctacgcgc
     7621 cagataacga aaacaagggc aaccagcgcc aacgcaacca ctaacagagc agggaattta
     7681 ctgcgaggag cttttttcgg cgtactttcc atgagcgcgt ctcaaataga ttagaaaaat
     7741 gccagccaga acagcatggc gtagagagca aaaagggcgg tataaataat tccgacaaat
     7801 gccagattga tatttgcccg ctgaataact cgcctcgtga tgagcgtcaa aataaggctg
     7861 gcaatggcgc agaaaaacca gctgggataa taagcgccga tcaccgggat tgccggagat
     7921 aatgagcatc ccgaaaccat gaagacggga attatccagg ctgttttttt gagttgcatc
     7981 gccatgcgag agagaactgt tggcatatta aatacatcct gtctgctgcg aacaatatct
     8041 gtagtgaata tcaatatcca ttgaaggcgt cagtatggct attttcttga tgaataaaaa
     8101 tagctttatt cagcca
//
LOCUS       DAPHKZ010000175         7993 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.176, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000175 DAPHKZ010000000
VERSION     DAPHKZ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7993
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.176"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..883)
                     /locus_tag="RH288_004216"
     CDS             complement(<1..883)
                     /locus_tag="RH288_004216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HDV4033205.1"
                     /translation="MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQG
                     AHLLSWKPAGEEEVLWLSNNTPFKNGIAIRGGVPVCWPWFGPAAQQGLPAHGFARNLP
                     WTLKSHREDANGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLESHGEFETT
                     SALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKEDVLTDGIQTFPDRTDRVYLNPQDCS
                     VINDEALNRIIAVGHQHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQK
                     VTKEKPAHLAQSIRVAKR"
     gene            complement(967..1962)
                     /gene="gapA"
                     /locus_tag="RH288_004217"
     CDS             complement(967..1962)
                     /gene="gapA"
                     /locus_tag="RH288_004217"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDV4033206.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLT
                     DETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            2304..2717
                     /gene="msrB"
                     /locus_tag="RH288_004218"
     CDS             2304..2717
                     /gene="msrB"
                     /locus_tag="RH288_004218"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDV4033207.1"
                     /translation="MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVY
                     HCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLRFTDGENGEEING"
     gene            2759..3031
                     /locus_tag="RH288_004219"
     CDS             2759..3031
                     /locus_tag="RH288_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416291.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HDV4033208.1"
                     /translation="MNLDDIINSMMPEVYQRLSTAVELGKWPDGVALTEEQKENCLQL
                     VMLWQARHNIEAQHMTIDTNGQMVMKSKQQLKEDFGISAKPIAMFK"
     gene            3401..4477
                     /locus_tag="RH288_004220"
                     /pseudo
     CDS             3401..4477
                     /locus_tag="RH288_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
     gene            4504..5883
                     /locus_tag="RH288_004221"
     CDS             4504..5883
                     /locus_tag="RH288_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV4033209.1"
                     /translation="MEQITKPHCGARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGL
                     ILAQLKALGWTDNSTTATFSAITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASM
                     VVGAFSPNMDFLIACRFVMGVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSY
                     PLCSLIAMGLTPLISAEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEA
                     EKVMRSIEEGVIRQTGKPLPPVVIADDGKAPQAVPYSALLTGVLLKRVILGSCVLIAM
                     NVVQYTLINWLPTIFMTQGINLKDSIVLNTMSMFGAPFGIFIAMLVMDKIPRKTMGVG
                     LLILIAVLGYIYSLQTSMLLITLIGFFLITFVYMYVCYASAVYVPEIWPTEAKLRGSG
                     LANAVGRISGIAAPYAVAVLLSSYGVTGVFILLGAVSIVVAIAIATIGIETKGVSVES
                     LSIDAVANK"
     gene            5900..6943
                     /locus_tag="RH288_004222"
     CDS             5900..6943
                     /locus_tag="RH288_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HDV4033210.1"
                     /translation="MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVH
                     GFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCL
                     EGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHA
                     AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLIMAEQLGATVVI
                     NGTKEDTISRCQQFTEDMGADIVFETAGSAVTIKQAPYLVMRGGKIMIVGTVPGDSAI
                     NFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNN
                     KRDIIKGVIKISD"
     gene            6964..7800
                     /locus_tag="RH288_004223"
     CDS             6964..7800
                     /locus_tag="RH288_004223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDV4033211.1"
                     /translation="MLADIRYWENDATNKHYAIAHFNVWNAEILMGVIDAAEEAKSPV
                     IISFGTGFVGNTSFEDFSHMMVSMARKATVPVITHWDHGRSMEIIHNAWTHGMNSLMR
                     DASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPDQAAE
                     FVERTGCDSLAVAIGNQHGVYTSEPQLNFEVVKRVRDAVSVPLVLHGASGISDADIKT
                     AISLGIAKINIHTELCQAAMVAVKENQDQPFLHLEREVRKAVKERALEKIKLFGSDGK
                     AE"
     gene            7805..>7993
                     /locus_tag="RH288_004224"
     CDS             7805..>7993
                     /locus_tag="RH288_004224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDV4033212.1"
                     /translation="MDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDA
                     INEATIISRLGHRTALMSR"
BASE COUNT         2061 a         1777 c         2023 g         2132 t
ORIGIN      
        1 aacgtttcgc aacgcgaatg gattgcgcca gatgtgcagg tttctctttg gtcacttttt
       61 gcgtttctga agcgtaagcc gtttctacac aaacaaatgt tttgtagcca tcatccggca
      121 tatcgcccat gctaattgaa agcgccggtc ccgggttcca gccgacaacg ttcagatgat
      181 gctggtggcc tacggcgata atacgattca gcgcttcatc attaatcacg ctgcaatctt
      241 gtggattcag atacacgcga tcggtacggt cagggaaggt ctgaatacca tcggtcagta
      301 catcttcttt cgcgtcattc actttatcaa tgaagcgatc gcccagccca ctgacgctta
      361 ccttagcgat atcacccacg ttaaagtagg tatgcagggc agaggtggtt tcaaattcgc
      421 catgtgattc aagatcgatt tcacaagttt tacccacgcg gaaatgcgct aacagcgtaa
      481 agtcgtgcgg ccagaatttt ttcgtctctt cgctttgcgt caattcaaaa gtcagcgcta
      541 cgccattagc atcttcacga tgtgatttca gcgtccacgg caggttgcgg gcaaaaccgt
      601 gcgcaggcag gccttgttgt gccgccggac caaaccacgg ccagcaaacc ggtacgccac
      661 cgcgaatagc gatgccattt ttgaacggtg tgttgttgct caaccacaga acttcttctt
      721 cacccgcagg tttccacgag agaaggtgtg cgccctgtaa tgcaaaagag gcttttacct
      781 ggggatgatc gaccacaatg aggtccagtt catccagttt acgacgggag aggacagggg
      841 agatttgttc gatgaccgga agggcaaaaa ttttcttaat catgacgcag tcctttaact
      901 tcattttatc aggtaaaaaa aagagcgacc gaagtcgctc tttttagatc acagtgtcat
      961 ctcaacttat ttggagatgt gagcgatcag gtccagaact ttgttggagt aaccggtttc
     1021 gttgtcgtac caggatacca gtttcacgaa gttgtcgttc agagcgatac cagctttagc
     1081 atcgaacacg gaagtgcaaa cttcgccgtt gaaatcggta gatactacgt catcttcggt
     1141 gtagcccaga acgcctttca tttcgccttc agcagcagct ttaacggcag ctttgatctg
     1201 ctcgtaagtt gcagcttttt ccagacgaac ggtcaggtca actacagata cgttcggggt
     1261 cggaacgcgg aacgccatac cagtcagttt gccattcagt tctggcagta ctttacctac
     1321 agctttagca gcaccggtag aggacgggat gatgttctgg gaagcgccgc ggccgccgcg
     1381 ccagtctttg tgagacgggc catcaacggt tttctgagta gcggtagtag cgtgaacggt
     1441 ggtcatcaga ccttcgatga tgccgaagtt atcgttgata actttagcca gcggagccag
     1501 gcagttggtg gtgcaggaag cgttggaaac gatgtcctgg ccagcatatt tgtcgaagtt
     1561 agcgccttta acgaacatcg gagtgttgtc tttagacgga ccagtcataa ccactttctt
     1621 cgcaccagcg gtgatgtgtt tacgagcagt ttcgtcagtc aggaacagac cagttgcttc
     1681 agcgacaacg tcaacaccaa cttcgtccca tttcaggtta gccggatcac gttcagcggt
     1741 aacacggatt tttttaccgt taacgatcag atgaccgtct ttcacttcaa cggtaccgtc
     1801 gaaacggccg tgagtggagt catatttcag catgtatgcc atgtaatcag cgtctaacag
     1861 gtcgttgatt gcaacgatct cgatgtcaga acgtttctga gcagcacgga aaacaatgcg
     1921 accgatacgg ccaaaaccgt tgatacctac tttgatagtc atatattcca ccagctattt
     1981 gttagtgaat aaaaggttgc ctgtaaaatt acaaaaacct tacgcagcgt caagcggaat
     2041 cgtgtcaatc attgcgacaa atcaatcctg tgcctaagca ttacgcgact gactcgcctc
     2101 actcttcctt tgggcttgag accacatggg gtcggcgccc cgaattttaa agggcaatta
     2161 cgataaaaat gtgattttca tcacgattta ggagcagcca tttcgtcgag atcaagttta
     2221 ggacaaaatt ttgccagttg gtgttaatgt tttgttagaa tcagtcacgt aatgtgagca
     2281 cgattaaagt gagatgtgag caaatggcta ataaaccttc ggcagaagaa ctgaaaaaaa
     2341 atttgtccga gatgcagttt tacgtgacgc agaatcatgg gacagagccg ccatttacgg
     2401 gtcgtttact gcataacaag cgtgacggtg tatatcactg tttgatctgc gatgccccgc
     2461 tgtttcattc ccaaacaaag tatgattccg gctgtggctg gcccagtttc tacgaaccgg
     2521 taagtgaaga atccattcgt tatatcaaag acttgtcaca tggaatgcag cgcatagaaa
     2581 ttcgttgcgg taactgtgat gcccatctgg ggcatgtctt ccccgacggg ccgcagccaa
     2641 cgggcgaacg ttattgtgtt aactctgcct ctttacgctt taccgatggc gaaaacggcg
     2701 aagaaatcaa cggttgaaaa aacgattcag caacttattc cacaggagcg gaaaaattat
     2761 gaatcttgat gacattatca acagcatgat gcctgaggta taccagcgtt tgtcgaccgc
     2821 cgttgaactg gggaaatggc ctgatggcgt tgcgttgacc gaggaacaaa aagagaactg
     2881 cctgcaattg gtgatgctgt ggcaagcccg ccataatatc gaagcacagc atatgacaat
     2941 tgacacaaat ggtcagatgg tcatgaagag caaacagcag ttaaaagaag attttggtat
     3001 ctcagcaaag cctattgcca tgtttaagta agtggttcat cccctttttg cctcggctat
     3061 gaaggggata gccaacaatg accccacgac tcatctcaat tatctcgcca tgacctggct
     3121 aagtcccagt ccgatctctt gccgtcccgt tcacacctga atgacttctc ctgaacttaa
     3181 gtctcagacc tatttggccg gtaatccctc tcgaatttgc tctttttgcg ccccgccttc
     3241 catcaacctg taacagaccc agccattttc tgcgtaattg tgatctgagt tgtaaaacgc
     3301 agatcattat ctgtgtttta cagatttaat gttgacctca aaaatcatgt gggtaagtat
     3361 gatggccatc taagcaaaac taaacacaga ggatgacgca atgaaagcac tggctcggtt
     3421 tggcaaggcc tttggcggct acaagatgat tgatgtccca caacccatgt gtggcccgga
     3481 agatgtagtg attgaaatta aagccgcggc aatctgcggc gcagacatga agcactacaa
     3541 tgtcgatagc ggttctgatg agtttaactc tatccgcggc catgagttcg caggttgtat
     3601 tgcgcaggtt ggtgaaaaag tcaaagactg gaaagtgggg caacgcgtcg tatcggataa
     3661 cagcggtcac gtttgcggtg tttgtccggc ctgtgaataa ggtgattttc tgtgttgtac
     3721 agaaaaagta aaccttggtc tggataataa tacctggggc ggtggttttt ccaaatattg
     3781 tctggttcct ggtgaaattc tcaaaattca tcgtcatgcg ttgtgggaaa tccctgatgg
     3841 tgttgattat gaggacgcag ccgtacttga ccctatctgt aatgcctaca aatccatcgc
     3901 gcagcaatcg aaattccttc ctggtcagga tgtggtcgtc atcggcactg gcccactcgg
     3961 gctgttctcc gtacaaatgg cgcgaattat gggggcggta aatatcgtcg tcgttggtct
     4021 gcaagaagat gtggcggtcc gcttcccggt tgcaaaagaa ctgggtgcga cggcagtagt
     4081 aaatggttct accgaagatg tggtggcgcg ctgccagcaa atttgtggca aagacaatct
     4141 gggactggtg attgaatgct ccggtgccaa tatcgcactg aaacaagcca tcgaaatgct
     4201 ccgcccgaac ggggaagtgg tacgcgttgg aatgggcttc aaacctcttg atttctcgat
     4261 taatgacatt accgcctgga acaaaagcat cattgggcat atggcctatg actccacctc
     4321 atggcgtaac gctatcaggc tcttagccag cggcgctatc aaagtcaaac cgatgattac
     4381 gcatcgtatc ggcctgtcgc aatggcgcga agggtttgat gcgatggtcg ataaaaccgc
     4441 aatcaaagtg atcatgactt acgactttga tgaataacca ctctcctgaa ggaacgttat
     4501 cgcatggaac agataacaaa accgcattgt ggtgcacggc tggatcgctt accggattgc
     4561 cgctggcatt catcaatgtt tgccatcgtc gcgtttggct tgcttgtctg ctggagtaat
     4621 gccgttggtg gcttgatcct cgcgcagctg aaagcgttgg gctggacaga taattccacc
     4681 acagccacat tctcagcaat cacgaccgcc ggaatgtttc tcggtgcgct ggtgggcggc
     4741 atcattggcg acaaaaccgg tcgcagaaat gcgttcatcc tctatgaggc cattcatatt
     4801 gcctcgatgg ttgtcggtgc tttctcaccg aatatggatt ttcttattgc ctgccgtttt
     4861 gtgatgggag ttgggctggg agctttactg gttacactgt ttgctggttt caccgaatat
     4921 atgcccggta gaaatcgcgg aacgtggtcc agtcgggttt cctttattgg caactggtca
     4981 tatccgctct gttcattgat tgcgatggga ctcacgccgc tgattagtgc agagtggaac
     5041 tggcgggtac aactgcttat ccctgcaata ttgtcgctta tcgctacggc gctggcctgg
     5101 cgctactttc ctgaatcccc gcgctggctg gaatcgcgcg gacggtatca agaagccgag
     5161 aaagtcatgc ggagtataga agaaggcgtc atacgccaga cgggtaaacc tttgccgcct
     5221 gtggttattg ctgatgacgg taaagcgcca caagcggtgc cgtattcagc cttactgaca
     5281 ggagtattac tgaaacgcgt gatattaggc tcttgtgtgc tgattgccat gaacgttgtg
     5341 cagtacacac taattaactg gttgccaaca atattcatga cccaggggat taatttaaaa
     5401 gactcgattg ttttaaatac catgagtatg tttggcgcgc catttggtat ttttattgcc
     5461 atgctggtga tggataaaat tccgcgtaaa acaatgggtg tggggctatt aatcctgatt
     5521 gcggtgctcg gatatatcta ttcactgcaa accagtatgt tgctcataac gttgattggt
     5581 ttcttcctga ttactttcgt ctatatgtac gtttgctatg cctcggcagt gtatgtccct
     5641 gaaatctggc cgacagaggc caaactccgt ggctccggtc tggcgaatgc ggtagggcga
     5701 atcagtggta ttgccgcacc ttatgccgtt gcagtgctgc tcagtagtta tggcgtaacg
     5761 ggagtcttta ttcttctggg ggctgtttca attgttgtcg caattgctat cgccaccatt
     5821 ggaattgaaa ccaaaggtgt ctccgttgaa agtttaagta ttgatgcagt agccaataaa
     5881 taatacgggt ggattcaaaa tgaaaaattc aaaagcaata ttgcaggtgc cgggcacaat
     5941 gaaaattatt tcagcagaaa taccagtgcc taaagaagat gaagttttga ttaaagtaga
     6001 atatgtcggt atttgtggtt cagatgtaca tggttttgaa tcaggcccgt ttattccgcc
     6061 taaagaccca aatcaagaaa ttggcctggg tcatgaatgc gccgggacgg ttgtggctgt
     6121 gggaagccgc gtgcgcaaat ttaaaccggg ggatcgggta aatatcgaac ctggcgttcc
     6181 ttgcggtcac tgtcgttact gtctggaagg caaatataac atctgcccgg acgttgattt
     6241 tatggcgaca caacccaact accgcggcgc attaacgcac tatctgtgtc atccggagag
     6301 ctttacttac aaactgccag acaatatgga cacgatggaa ggggcgctgg tggagcctgc
     6361 cgcagtcggg atgcatgccg cgatgctggc agatgttaaa ccgggtaaga agataattat
     6421 tctgggagca ggttgtattg gtttgatgac gttgcaagcg tgcaaatgcc tgggcgcaac
     6481 ggaaattgcc gtcgttgatg tgctggaaaa acgtctgata atggcggaac aacttggtgc
     6541 gacagtggtt attaacggca caaaagaaga cactatttca cgctgtcagc aatttaccga
     6601 agacatgggc gcagatattg ttttcgaaac agcgggttct gcggtcacca ttaaacaggc
     6661 accttatctg gtaatgcgcg gcggtaaaat tatgattgtt ggtactgtac cgggcgattc
     6721 ggcaatcaat ttcctcaaaa tcaatcgcga agtcactatc cagacggtat tccgctatgc
     6781 caatcgttat ccggtcacga ttgaagctat ttcttcaggg cgattcgatg tgaaatcgat
     6841 ggtgacgcat atttacgatt atcgggatgt acaacaggca tttgaagagt cagttaacaa
     6901 caaacgcgac attattaaag gcgttattaa aattagcgat taattaatac gggagaacag
     6961 aatatgctcg cagatatcag atattgggaa aacgatgcca caaataaaca ttatgcaatt
     7021 gcccatttta acgtatggaa tgcagaaata ttgatgggcg ttatcgacgc agccgaagaa
     7081 gcgaaatcac cggttattat ttcttttggt acaggttttg tcggcaacac ctcatttgaa
     7141 gatttctctc acatgatggt atcaatggca cgaaaagcaa ctgtgccggt aataactcat
     7201 tgggatcatg gtcggagtat ggagattatt cataacgcct ggactcatgg tatgaattca
     7261 ttaatgcgtg atgcttctgc atttgatttc gaagaaaata ttcgtttaac caaagaggct
     7321 gtcgatttct tccatccgct gggtattccg gtagaggcgg aattagggca tgtcggtaat
     7381 gaaaccgttt atgaggaagc gctggcgggc tatcactata ccgatcctga ccaggcggct
     7441 gaatttgttg aacgtacggg ctgtgactca ttggctgtcg ccatcggcaa ccagcatggg
     7501 gtttatacgt cagagccaca attgaacttt gaggtcgtca aacgcgtacg tgatgccgtt
     7561 tctgttccgc tggttttgca cggtgcatcg gggatcagtg atgccgacat taaaactgca
     7621 atttcgttgg gtatcgcgaa aatcaacatt catacggagc tctgtcaggc cgcaatggtc
     7681 gcagtgaaag aaaaccagga tcagcctttc ctgcatttag aacgtgaagt acgtaaagct
     7741 gtaaaagaac gggcattgga aaaaattaaa ctgttcggtt ctgatggcaa agcggaataa
     7801 tgatatggat aatctcgacg ttatttgtat aggtgccgct attgttgata ttccattgca
     7861 accggtcagt aaaaatatct ttgatgtgga ttcttatcct cttgaaagaa tcgcaatgac
     7921 caccgggggt gatgcaataa atgaagcaac aattatttct cgtctgggcc atcgtacagc
     7981 attaatgagc cgt
//
LOCUS       DAPHKZ010000176         7902 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.177, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000176 DAPHKZ010000000
VERSION     DAPHKZ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7902
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.177"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            56..574
                     /locus_tag="RH288_004225"
     CDS             56..574
                     /locus_tag="RH288_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-tetronate isomerase"
                     /protein_id="HDV4033213.1"
                     /translation="MNINRDKIVQLVDTDTIENLTSALSQRLIADQLRLTTAESCTGG
                     KLASALCAAEDTPKFYGAGFVTFTDQAKMKILSVSQQSLERYSAVSEKVAAEMATGAI
                     ERADADVSIAITGYGGPEGGEDGTPAGTVWFAWHIKGQNYTAVMHFAGDCETVLALAV
                     RFALAQLLQLLL"
     gene            complement(618..2663)
                     /gene="dcp"
                     /locus_tag="RH288_004226"
     CDS             complement(618..2663)
                     /gene="dcp"
                     /locus_tag="RH288_004226"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HDV4033214.1"
                     /translation="MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIA
                     AIALNPQMPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAEL
                     ANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKV
                     LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWL
                     IPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLL
                     GFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQP
                     WDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYH
                     PDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNKTHPVIYNVCNYQ
                     KPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHW
                     ATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEE
                     NEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD
                     GYQWFVEQGGLTRENGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGLNI"
     gene            2800..3546
                     /gene="ydfG"
                     /locus_tag="RH288_004227"
     CDS             2800..3546
                     /gene="ydfG"
                     /locus_tag="RH288_004227"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HDV4033215.1"
                     /translation="MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDEL
                     GDNLYIAQLDVRNRAAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETM
                     IDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWW
                     VSTLPAHVNINTLEMMPVTQSYAGLNVHRQ"
     gene            3635..4321
                     /gene="ydfH"
                     /locus_tag="RH288_004228"
     CDS             3635..4321
                     /gene="ydfH"
                     /locus_tag="RH288_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YdfH"
                     /protein_id="HDV4033216.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAA
                     SMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLK
                     ATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIR
                     QENSDWFSEE"
     gene            4498..4701
                     /gene="ydfZ"
                     /locus_tag="RH288_004229"
     CDS             4498..4701
                     /gene="ydfZ"
                     /locus_tag="RH288_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HDV4033217.1"
                     /translation="MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRG
                     KTVVVEGCEEKLAPLDLIRLGMN"
     gene            complement(4736..6196)
                     /locus_tag="RH288_004230"
     CDS             complement(4736..6196)
                     /locus_tag="RH288_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDV4033218.1"
                     /translation="MGNNLLSAKATLPVYDRNNLAPRIVHLGFGAFHRAHQGVYADIL
                     ATEHFSDWGYYEVNLIGGEQQIADLQQQDNLYTVAEMSADVWTARVVGVVKKALHVQI
                     DGLETVLAAMCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVAADVQNPHQPKTATG
                     VIVEALARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAVDVKLAQWIEDNVTFP
                     STMVDRIVPAVTEDTLAKIEQLTGVRDPAGVACEPFRQWVIEDNFVAGRPEWEKAGAE
                     LVSDVLPYEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHYRYAAYGLMLQEQAP
                     TLKVQGVDLQDYANRLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKF
                     DLLALGVAGWMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGKARVQSLLAIKAIF
                     GDDLPDNSLFTARVTETYLSLLAHGAKATVAKYSVK"
     gene            complement(6285..7568)
                     /gene="ydfJ"
                     /locus_tag="RH288_004231"
                     /pseudo
     CDS             complement(6285..7568)
                     /gene="ydfJ"
                     /locus_tag="RH288_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582800.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter YdfJ"
BASE COUNT         2086 a         2019 c         1819 g         1978 t
ORIGIN      
        1 cgagcataca gaaaaagcaa atcaccttta catataaaag cgtggacaaa aaacagtgaa
       61 cattaataga gataaaattg tacaacttgt agataccgat actattgaaa acctgacatc
      121 cgcgttgagt caaagactta tcgcggatca attacgctta actaccgccg aatcatgcac
      181 cggcggtaag ttggctagcg ccctgtgtgc agctgaagat acacccaaat tttacggtgc
      241 aggctttgtt actttcaccg atcaggcaaa gatgaaaatc ctcagcgtaa gccagcaatc
      301 tcttgaacga tattctgcgg tgagtgagaa agtggcagca gaaatggcaa ccggtgccat
      361 agagcgtgcg gatgctgatg tcagtattgc cattaccggc tacggcggac cggagggcgg
      421 tgaagatggt acgccagcgg gtaccgtctg gtttgcgtgg catattaaag gccagaacta
      481 cactgcggtt atgcattttg ctggcgactg cgaaacggta ttagctttag cggtgaggtt
      541 tgccctcgcc cagctgctgc aattactgct ataaccaggc tggcctggcg atatctcagg
      601 ccagccattg gtggtgttta tatgttcaag ccacgatgtt gcagcatcgg cataatctta
      661 ggtgccttac cgcgccattg tcgatacagg cgttccagat cttcgctgtt acctctggaa
      721 aggatcgcct cgcgaaaacg cagcccattt tcacgcgtta atccgccctg ctcaacaaac
      781 cactgataac catcatcggc caacatttgc gtccacagat aagcgtaata acctgcagca
      841 tatccgccac caaaaatatg ggcgaaataa ctgctgcgat agcgtggcgg tatagcagga
      901 agatccatat tttccgccac cagcgcccgc aattcaaaat catcgacatc ctgcattgct
      961 tcgttttctt ccaggcaatg ccagcgcata tcgagaagtg cggcgctaag cagttcgctc
     1021 atctcatacc ctttgttgaa caggctggca ttacgcattt tctgttgcag ttcgtcaggc
     1081 attgctgccc cgctctgata atgccgggcg tagcgagcga atacctgcgg atgcgttgcc
     1141 cagtgttcgt tgatttgcga cggaaattcg acaaaatcac gcggcgtgtt ggtgccggaa
     1201 agcgtggcat aacgctggcg ggcaaaaagg ccgtgcagcg tatgaccaaa ttcatggaat
     1261 aaggttatga catcatccca gagtaacaac gcaggctcac cggcagcggg tttctgataa
     1321 ttgcagacgt tataaattac cggatgtgtt ttattaagcg ttgattgctc aacaaaattg
     1381 cccatccatg caccgccgct ttttgaatca cgggcgaaga aatcaccgta aaataacgcc
     1441 agccccacgc cattatgatc aaaaatttcc cacacacgaa cgtcaggatg gtagacagga
     1501 atatcaaaac gttcgacaaa cttaataccg aagagctgat tcgcggtcca gaatacacct
     1561 tcatttaaca ccgtgtttaa ttcaaaatat ggcttgagct gcgcctcatc aagatcaaat
     1621 ttctcccgcc gtacctgttc cgcataaaat gcccagtccc acggctgcgc gctaaacccg
     1681 ccctgctgct tatcgataac cgcctgtatg gaggctaatt catcgctcgc acgttgacgc
     1741 gccgctggaa caatttcccg cataaagtta agtgctgctt caggtgtttt tgccatctga
     1801 tcggcgattt tccatgcggc ataatgagga aaaccaagta gtgttgcctg ttgtgcacgg
     1861 atctccacca gacgttgaat gatagcgcgg gtatcattgg catcattttt ttccgctcgc
     1921 gtccagcccg caataaacag tttttcacgc gtcgcacgat cgcgcatttc ggcaagcgcc
     1981 ggttgttggg tggtattcag cagcggaatc agccatttgt tatccagacc tttctcgcga
     2041 gccgcctctg ccgccagcgc aatctcttgc tcactcattc ctgccagctg cgcgatatcg
     2101 ttcacaacca gaccgccgga tttatttgct gccagtaatc gctggttaaa ctggctggtc
     2161 agggtcgcag cttctgtatt cagtactttt aattttgctt tatcagcttg cgcaagtttg
     2221 gctccggcaa ggacaaaacg ttgatgaatc acctccacca ggcggatgga ttcactatca
     2281 agccccaggg attcacggcg ctgccagaca gcatctaccc gcgcgaataa ttcaccgttc
     2341 agatagatat cattagccag ttccgccagt tcagcggaaa actgctcgtc aagacgctgt
     2401 aattcatcat tggtatgcgc cgcagtcatc gcaaaaaaga cgctggtaac gcgggtaagt
     2461 aattctccgc tttgttccag tgccagaata gtattgttga aatcaggcat ttgcgggtta
     2521 agcgcgatgg cagcaatttc tgcccgcttt tgctgcattc cctcatcgaa tgccgggcga
     2581 tagtgatgat tggcaatttg atcaaaatgg ggagccagat acggcagtgt gctttgcaca
     2641 aggaaaggat tcattgttgt cattttcttc tcctgaacgc gaggtgttcc atagcgtagg
     2701 cttactgata acggagtgca atcttgcaat ccagtattac ccgctcttaa gcatcccgtg
     2761 ctatgttatt gacacacaaa agcgttgagg aacagtgaga tgatcgtttt agtaactgga
     2821 gcaacggcag gttttggtga atgcattact cgtcgtttta ttcaacaagg gcataaagtt
     2881 atcgccactg gccgtcgcca ggaacggttg caggagttaa aagacgaact gggagataat
     2941 ctgtatatcg cccaactgga cgttcgcaac cgcgccgcta ttgaagagat gctggcatcg
     3001 cttcctgccg agtggtgcaa tattgatatc ctggtaaata atgccggcct ggcgttgggc
     3061 atggagcctg cgcataaagc cagcgttgaa gactgggaaa cgatgattga taccaacaac
     3121 aaaggcctgg tatatatgac gcgcgccgtc ttaccgggta tggttgaacg taatcatggt
     3181 catattatta acattggctc aacggcaggt agctggccgt atgccggtgg taacgtttac
     3241 ggtgcgacga aagcgtttgt tcgtcagttt agcctgaatc tgcgtacgga tctgcatggt
     3301 acggcggtgc gcgtcaccga catcgaaccg ggtctggtgg gtggtaccga gttttccaat
     3361 gtccgcttta aaggcgatga cggtaaagca gaaaaaacct atcaaaatac cgttgcattg
     3421 acgccagaag atgtcagcga agccgtctgg tgggtgtcaa cgctgcctgc tcacgtcaat
     3481 atcaataccc tggaaatgat gccggttacc caaagctatg ccggactgaa tgtccaccgt
     3541 cagtaatttt tatacccggc gtaactgccg ggttattgct tgtcacaaaa aagtggtaga
     3601 ctcatgcagt taactcactc acaagcaaga acgaatgacc gtcgaaacgc aacttaatcc
     3661 cacacagcct gtcaatcagc agatttatcg tattcttcgt cgcgacattg tccattgcct
     3721 gattgctcca ggcacaccgt tgtcggaaaa agaagtttct gttcgtttca atgtgtcacg
     3781 ccagccggtt cgtgaagcct ttattaaact ggcggaaaac ggcctgattc aaattcgtcc
     3841 gcaacgtggc agctacgtca acaaaatttc catggcccag gtgcgcaacg gcagttttat
     3901 ccgtcaggcc attgagtgcg cggtggcgcg tcgggcggcg agcatgatta ccgaaagcca
     3961 gtgctatcaa ctggaacaaa atcttcacca gcaacgcatt gccattgagc gcaagcaact
     4021 ggatgatttt tttgaacttg atgacaactt ccatcaactc ctgacgcaga ttgccgactg
     4081 tcaactggcg tgggatacca ttgagaacct gaaagcgacc gttgatcgcg tgcgctatat
     4141 gagtttcgac cacgtttctc caccagaaat gctgttacgc cagcatcttg atattttctc
     4201 tgccctgcaa aaacgtgatg gcgatgcggt agaacgtgca atgacgcaac atttgcagga
     4261 aatcagcgaa tccgtgcgcc agatccgcca ggaaaacagc gactggttta gcgaagagta
     4321 attcatttcc tctcatccca tccggggtga gagtcttttc ccccgcctta tggctcatgc
     4381 atgcatcaaa aaagatgtga gcttgatcaa aaacaaaaaa tatttcactc gacaggagta
     4441 tttatattgc gcccgttacg tgggcttcga ctgtaaatca gaaaggagaa aacacctatg
     4501 acgacctacg atcgtaaccg taacgcaatc accactggca gccgtgttat ggttagcggc
     4561 accggtcaca ctggcaagat cctgtcgatt gatactgaag gtctgaccgc tgagcaaatc
     4621 cgccgcggaa aaaccgtagt tgttgaaggt tgtgaagaga aactggcacc actggacctg
     4681 attcgtctcg gcatgaacta agcgtgtgaa tgccgccgat ggcggcattg cttttttact
     4741 tcacggaata ttttgccacg gtcgctttcg cgccatgcgc taataaagac aagtacgttt
     4801 ccgtcactct tgcagtaaac aaactattgt ctggcaaatc atcaccaaag atcgccttaa
     4861 tcgccagcaa tgactggacg cgcgctttcc cttcggcact actttgtaca gccttctgaa
     4921 taacaggtaa cagtgggtca ctgatttcta tcggatttcc ctgttcatca acaccaccga
     4981 cataacgcat ccaacccgcg acgcccagcg ccagcagatc gaacttgctg tcatgcgcca
     5041 gatgccagcg aacagaatcc aacatccgct gtggcaattt ctggctacca tccatcgcaa
     5101 tctgccaggt tcgatgacgt aacgccgggt tgctatagcg tgcaattaat cggttagcgt
     5161 aatcttgcaa atcaacgccc tgcactttca acgtcggcgc ttgttcctgc aacatcaagc
     5221 catacgccgc ataacgataa tgttcatctt ccatacagtc attaatgtgc tgatatcctg
     5281 caagataccc cagatacgcc aggaatgaat gactgccgtt gagcatgcgc aacttcatct
     5341 cttcataagg cagcacatcg ctaaccagtt cggctcccgc tttttcccat tccggacgtc
     5401 cggcaacaaa gttatcttct attacccact ggcggaaagg ttcacaggca acgcccgcag
     5461 gatcgcgcac accggtaagt tgttcgattt tcgccagcgt atcctctgtc actgcgggca
     5521 caatacggtc caccattgtt gatgggaaag tcacgttatc ttcgatccat tgtgccagtt
     5581 ttacatcaac ggcttgtgcg taggaagtga caacgtcacg cataacatga ccgttttctg
     5641 gcatgttgtc acatgacatg acggtaaatg cgggaagtcc tgccgcttta cggcgagcca
     5701 gcgcctcaac aatcacccct gttgctgttt tcggctggtg gggattttgc acgtcggcag
     5761 ctaccatcgg gtgatcgagc attaactgtc cggtcgccgg agagtggaaa tacccttttt
     5821 cggtgattgt cagagagaca atcgcgattt gcggttcaca catcgctgcc aacacggttt
     5881 ctaagccatc tatctgtacg tgcaaggctt ttttaacgac gccaacgacg cgagccgtcc
     5941 acacatcggc cgacatttcc gcaacggtat aaagattatc ttgctgttgt aaatcggcaa
     6001 tttgctgttc gccgccgatt aagttgacct cataatatcc ccagtcactg aaatgttccg
     6061 tagcaagaat atcggcatac acaccctgat gcgcacggtg aaatgcacca aagcctaaat
     6121 gaacaattct tggagccagg ttattacgat cataaacagg gagtgtcgct tttgctgata
     6181 acaaattatt tcccataaca attccttaaa tataaatatg gcaagctata tgttttgtta
     6241 tatgaataaa aatcccctct ccggtaagag aagggattaa gggtttacag acttctggaa
     6301 ggttgcgcag ctcttacaac acgcggttga tcttccgcag cgtcttccag cgcacttaaa
     6361 tcacggtctt tcacctctgg cattttcagc gcagagatta aaccaatcac tgaatatgcc
     6421 atgatcataa tggcgatcgg ataccaggat tccgtcatgg tgcagaaaat acccgccagg
     6481 ataggaccaa aaccggaagc gataagacca ccaatttctt tagaaatagc catccgggta
     6541 aagcggtttt tacagccgaa catttctgcc atggtaatat tttccagagc aaataatccc
     6601 agcaccgcac agttatgaat cacaatcagt gcaaccataa tggtgctcgg ggcatagctt
     6661 ttatctacaa tgatagaaag cattggccat gccagcacaa tcgcggaggt attcataata
     6721 atatacggga tccggcgacc aattttatcg gataaccaac caaggaacgg aatggtcata
     6781 aagccgagaa tcgaactgat catcaatgca tctgttggaa ttgctttgtt aaacaataac
     6841 gtctgcacta aatagcctgc aaggaaagtc tgaattaacc cggagttacc cgcctgacca
     6901 aaacgcagcc ctgttgccag ccagaaggat ttgctctgga acatgctacc agcaggtgca
     6961 ggttttgctg tcggttggtt actgtcgtta accttctcaa agaccgggct ttctttcaga
     7021 ttcatacgca accagatagc aaagaccatc acgacaacgc tcgccaggaa cggtatacgc
     7081 catccccacg ccagcagttc ctctttactg agaatgaaga acataaaggc ccagattgcc
     7141 gttgcgctca aggttccgca gttagttccc atagccacaa atgaggagat aattccgcgc
     7201 ttaccttttg gcgcatattc cgccagcatc gtaccggcac cggaaatttc cgcacctgca
     7261 cccaacccct gaataatacg caacgtcacc agcaagatgg gtgcaaaaac accaatctgt
     7321 gcataggtcg gtaacacacc aattaaggtg gtacagatcc ccatcatggt gatggtaata
     7381 aagagcactt ttttacgccc tattctgtcg cccattttgc cgaaaataaa tgctccgaca
     7441 atacgcgcca cataacctgc accgtaggtt cccattgcca gaattaacgc cattgccgtt
     7501 gatgattcag gaaaaaatat ttcatgaaac actaacgctg cgccgagcga atataactgg
     7561 aaatccataa ttcacaggtg ttttttccca tcctgtggtt tccttggcgt tttctaggtt
     7621 ttttcagata gttgcatttt ttaaaaagca tcctaagttc gatctcagtg tctatctggg
     7681 gcctatttct gtcccatata tgccccaaaa aaactcccca acagataagt agttttttca
     7741 tggatttatg cgtaaaatca agaacggctg gaaatcattc aatactcaca ctatcgaaaa
     7801 atttaccagc caaccgcagc acgttcttgc ataaggcgtg tctgcggttt ttcaactatt
     7861 cagatacatc actcccatca cattcattcc tccgcatcaa ag
//
LOCUS       DAPHKZ010000177         7739 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.178, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000177 DAPHKZ010000000
VERSION     DAPHKZ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7739
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.178"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            93..311
                     /locus_tag="RH288_004232"
     CDS             93..311
                     /locus_tag="RH288_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312842.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HDV4033219.1"
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQ
                     QFPVRKAKGGRQKGEVVGVDDQCKEHKE"
     gene            529..771
                     /locus_tag="RH288_004233"
     CDS             529..771
                     /locus_tag="RH288_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033220.1"
                     /translation="MNSLAGIDMGRILLDLSNEVIKQLDDLEVQRNLPRADLLREAVD
                     QYLINQSQTARTSVPGIWQGCEEDGVEYQRKLREEW"
     gene            complement(1101..2030)
                     /gene="fdhE"
                     /locus_tag="RH288_004234"
     CDS             complement(1101..2030)
                     /gene="fdhE"
                     /locus_tag="RH288_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HDV4033221.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLREL
                     AENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKH
                     WQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
                     WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKDPKIEAV
                     ADDLASLVLDARMEQEGYARSSINPFLFPGEGE"
     gene            complement(2027..2662)
                     /gene="fdoI"
                     /locus_tag="RH288_004235"
     CDS             complement(2027..2662)
                     /gene="fdoI"
                     /locus_tag="RH288_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HDV4033222.1"
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLM
                     QIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     gene            complement(2659..3561)
                     /gene="fdoH"
                     /locus_tag="RH288_004236"
     CDS             complement(2659..3561)
                     /gene="fdoH"
                     /locus_tag="RH288_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase O subunit beta"
                     /protein_id="HDV4033223.1"
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKC
                     TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHY
                     VGVGPNRADEEENNLHEEKDEERK"
     gene            complement(3574..6624)
                     /gene="fdnG"
                     /locus_tag="RH288_004237"
     CDS             complement(3574..6624)
                     /gene="fdnG"
                     /locus_tag="RH288_004237"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(6037..6039),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HDV4033224.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFI
                     HSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLS
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIR
                     SGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYD
                     KSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCE
                     YIAETSAHDKTASFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNK
                     NKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAERGGANPDQVLNMTWNY
                     AIPHEPSSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRDDGTTSCGCWIF
                     AGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     LQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            6818..7651
                     /gene="fdhD"
                     /locus_tag="RH288_004238"
     CDS             6818..7651
                     /gene="fdhD"
                     /locus_tag="RH288_004238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDV4033225.1"
                     /translation="MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVA
                     LVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSS
                     RRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDF
                     QPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLS
                     N"
BASE COUNT         1777 a         1991 c         2067 g         1904 t
ORIGIN      
        1 aaaacaacat gcaaaaatcc gcttttttta aatgattttc cggcgtaatt ttcgcacata
       61 cattaatgag taatatatgt aaggtattgg taatggcgat gaatacggtt tttcttcatt
      121 tatcagaaga ggcaattaaa cggctgaaca agcttcgggg ctggcgtaag gtttcacgat
      181 ctgcaatttt acgcgaagcg gtagagcaat atctggaacg tcagcaattc ccggtgcgta
      241 aagcaaaggg aggcaggcaa aagggggagg tagttggtgt tgatgatcag tgtaaggagc
      301 ataaggaatg acaaaaattt ttcattcttg aatataaaaa acagatgccc ttattctggt
      361 attaatacaa ggctgtttta cttgaactta taataactgc aactgttaca tcatatctgg
      421 aaaacgcctc gcaaaaataa aaaatgatgc gtaaatgagc tttctttaaa gattcggcaa
      481 gggtactttt ctctccatag attcaaaaat gatattggcg agatatttat gaactctctg
      541 gcaggtatag atatgggcag aattttactc gatttatcga atgaggtgat taagcaactt
      601 gatgatctcg aggtgcagcg taatcttcct cgtgcggacc tattaaggga agcggtagat
      661 caatacctga taaatcaatc gcaaacagca agaaccagtg ttcctggcat ctggcaaggg
      721 tgtgaggaag atggtgtcga atatcagcgt aagctgcgcg aggaatggta atgggaaaaa
      781 atgatgtcaa tcagattgct gacaacgtgc gcgttgttca tgccggatgc ggcgtgaacg
      841 ccttatccgg cctacaaagt cgtataaatt caatgtattg cagtttattg gtaggcctga
      901 taagcgcagc gcatcaggca atcttacgct tgtcatcagt ctcatgccca taaccttatt
      961 gatgtggtgg tgggtaaatt gaggccaaac cggcactggc ggcatagctt gaggtggtaa
     1021 cgcggaatac gagagatggt gtcgtcacac cctatgagct gtaatccggg cgacctgcgc
     1081 cacccggaaa acgtcagaga ttactctcct tcacccggaa acaggaacgg gttgatggaa
     1141 ctgcgggcat agccttcttg ctccattcgt gcgtccagta ccagagaggc gaggtcatct
     1201 gctacggctt cgatttttgg atctttttcc tgatagagaa ttttcaggta agtgccgcag
     1261 tcatcgcagc tttcggcttt aatcgcggcc tgttcgtcat ccagcgacca gtaatgcagt
     1321 ttgccgctct gctcgcagtt gctgcatttt acgcgcacta cgtgccattc agtttcacac
     1381 aggttgcagt gcaggtaacg tagcccctga gtggtgccaa tttgcaccat gctggacacc
     1441 ggcatagaac cacaaaccgg gcaatattga cgttgctcgc cgtattcagc gcgggctttg
     1501 ccggggatca gattggccat ctgcgcccag tagagcgaca gtgcagccca gataaacggc
     1561 gctttatcgc tgctgacgga cgagaaatca gaggcaaaca gcgcgctggc catatcttcc
     1621 agctcctgag tcgatgcctt ctccagattc tcaatcactg ccagcgccgg gccgctcatt
     1681 tcaggtttca gctcagcaat cagcgccatc agcagctttt gccagtgctt atcacgcggc
     1741 agaacgtgaa tatccagcgg gggcttgcct tgtgcgctgg cttctttaat gcgcgcagtc
     1801 agatccatct ccagcggatg gtcgtacagc accacttcct gggcgtgggc gataagcgca
     1861 gcaaagcgca ggtaatcacc cagaggatta ttttctgcca gctcgcgcag acgctcggcg
     1921 cggcggttgt ataaattctt gagccgaggg aacaataacg gcggaatcat atccgccgta
     1981 cgtttctcgc ttgaacccag ctcatcttgc gggattatgc gaatactcat tcagctttct
     2041 tttccgttgt cttgcggacc tcacggtacc agcgcgggtg atgtttcttc gcccaggcgc
     2101 tggtaaccca tccttccacc atggcggtaa tcgtgccttt cacccaaagg gcggcgtaga
     2161 tatgcaccat gataaccaca attaacgcca ctgcggcaaa tgaatgcagc attaacgcga
     2221 atcggatcac cgggattgag aaagcaggcg caaaataagg acgccagata atcacgccgc
     2281 tcaccagcag cagaaccagg aaaataatcg ccgcccagaa aacgcatttc tgaccgaagt
     2341 tataacgccc ggtgtcacct acttcctcgt tgacgacgat cttacgaata ttcttcgccc
     2401 aaaagatatc atcccgattg attaggttgt gatgccagta acggaaaaac atgatgatga
     2461 acgaggcaaa cataaccacg ccgacaaacg ggtgcagaat tcgcgccagc tgcggtgtgc
     2521 ccatgatttg catcaaccag ttgaaggacg ggaacaaaaa gcccagcccg ctcaccgccg
     2581 ccaggatgaa gcagaaggcg gtgatccagt ggttgatacg ttccggcgcg gtgtagcgca
     2641 cgatggtgtc acgtcgtttc atttgcgctc ctcgtctttc tcttcgtgca gattattctc
     2701 ttcctcatcc gcacggttcg gaccgacacc cacgtagtgg aagatactgg ccgcaaaggt
     2761 agccgcaaag ccaacagccg cgagcggttt ccagatgcct ttccagaatt tcacggtttc
     2821 gctgatttcc gggttctccg gcaagccatg atacagattt ggcttgtcag catggtgcag
     2881 cacgtacatg acgtgtgtac caccgacgcc tgccggatcg tacagacccg cattgtcgta
     2941 accgcgggtt ttcagctcag caacgcgctc gctcgccagc gttttcatcg actctttcgt
     3001 accgaagtga atcgcgcccg ttgggcaggt cttcacgcag gctggttctt gcccaaccac
     3061 cacgcggtca acgcacagcg tacatttgta gacgcggttg tcttccgggt tgaggcgcgg
     3121 aatgtcgaac ggacagcccg caatgcaata accgcagcca atgcactgct cggactggaa
     3181 gtcgacgata ccgttggcat actgaataat tgcaccttcc gccgggcacg ctttcaggca
     3241 gcctggatcg gaacagtgca tacagccgtc tttgcggatc agccattcca gtttgtcgtt
     3301 ctgctccact tccgagaagc gcattaccgt ccacgatttg gcgcttaaat cattggggtt
     3361 gtcgtacacc ccaatgttat tgccgacggt atcgcgaatg tcgttccact ctgaacacgc
     3421 cacctgacag gctttacagc cgatacaggt ggtaacgtcg atgagtttcg ccacttcttc
     3481 ctggaagtcc cgcgcctgag gcgcgggggt cagaccgtta gtcgcggaac gacgaatgat
     3541 atcttgagat tgataagcca tatgtcgtct ccgttacacc ttttccacat tcacaaggaa
     3601 ggacttaaac tccggcgtct gcgtgttcgc atcaccaacg aatggcgtta aagtattggc
     3661 aataaagcct tttttagcta cgccttcata gccccagtga atcggaatac cgatggtatc
     3721 gatatctttg ccgttcgctt tcagcgtgcg aatacgtttg gtcaccaccg ctttggcttt
     3781 gatatagcca cggttggagg agactttcac ggtatcgccc tgggcaatgc caagtttatt
     3841 cgccagcgac tccccgattt ccacaaactg ctctggctgc aaaatcgcgt tcaacagcgc
     3901 gtgtttggtc cagtagtgga agtgctcggt cagacgatag gtggttccga catacgggaa
     3961 cttatcggct ttacccaatg cttcggcgtc gtctttaaag atacgtgcag ccgggttcga
     4021 gataacgttt ggatgcagcg ggttagttcc cagcggcgtt tcaaacggct cgtagtgttc
     4081 cgggaacgga ccttccgcca tcttatcgag ggcaaacaga cgccccatgc cttcctgctg
     4141 catgataaac ggcccgacgc cgctacccgg aggcgctgcg ctgtagtccg gaatatccca
     4201 gccggtccac ttagtgccgt cccatttcag caactgacgc ttcggatccc acgggttacc
     4261 ctgcggatct gcggaggcgc ggttatacag aatgcggcgg ttaagcggcc atgcccatgc
     4321 ccagcccagc gtgttaccga ggccagacgg atcggcgtta tcacggcgtg ccatctggtt
     4381 gccttccggc gtccagctac cggcgaaaat ccagcagcca caggaggttg taccgtcatc
     4441 gcgcaattgg gcgaacgaac taagttgttg gcctttcttg acgataaccg caccggttgc
     4501 cggatcggta atatcggcca gcgccttacc gttgctctcc atcgccactt cttctgaaga
     4561 tggctcatgc ggaatggcgt agttccatgt catgttcagc acctggtccg ggttcgcgcc
     4621 accccgttcg gcatacatct tgcgcaagcg caggaagata ccggagagga tctcgccgtc
     4681 agtcagcgca atccccgggg cgtccgcacc tttccagtgc cactgtaacc agcgacctga
     4741 gttaacgata gaaccgttct cttccgcgaa gcaggtcgat ggcagacgga acacttcggt
     4801 ctggatcttc gacgagtcaa cttcgttcag ctcaccgtgg ttctgccaga agttagaggt
     4861 ttcagtgttc agtgggtcga tggtgacgag gaacttcagt ttcgacagac aaccgatcac
     4921 tttgtttttg ttcgggaatg aggcaacagg gttaaagccc tggcagatat agccattgac
     4981 cttgccctct ttcatcatct cgaagtattg caggacgtcg tagcctttat cccacttcgg
     5041 caaccagtca aagccccagc tattttccgc cgtcgcttta tcaccaaaga aggccttcat
     5101 catagagacg aagaatttcg ggtagttgcc ccagtagttt acctggcctt ccagcagcgg
     5161 ttttggcgtg ttggcggtaa ggtaggtttg cagatcggtc tgcttctcgc ttggcagcgt
     5221 catgtaacct ggcaggctct gcgacagcag ccccaggtcc gtcagcccct gaatattgga
     5281 gtgaccgcgc agggcgttaa cgccgccgcc tgccatcccc atattgccga gcagcagctg
     5341 gatcatcgcc atcgtacgaa tgttttgcgc accaacggag tgttgcgtcc agccgagggc
     5401 atacaggaac gaggcagttt tatcgtgagc actggtttct gcgatgtatt cgcagacttt
     5461 caggaacgcg tcttttggcg taccacagat gttttcaacc acatctggcg tgtagcggga
     5521 aacgtgctgt ttcagcaagt tccacacgca gcgcggatgt tgcagcgtgg tatcgcgttt
     5581 ggcgaagccg ttttcgtcca gttcataagt ccaggaggat ttatcgtact tgcgtttttc
     5641 cgcgtcgtag ccggtgaaca ggccatcttc aaagccgtaa tcctcacgca cgatcaggct
     5701 ggcgttggta taggcttcgg tgtattcgcg gttgaatttt tcattgttca gcaggtacag
     5761 caatacgcct gacaggaaag caatgtcagt accggaacga ataggggcat agtagtcagc
     5821 taccgccgcc gtacgcgtaa agcgaggatc gatcacaatc agcttcgcgc cgttgtgaat
     5881 tttggcttcc atcgcccagc ggaacccgac cgggtgagct tcagcggcgt taccgcccat
     5941 caccacgacg aggttggcgt tcttgatgtc gacccagtgg ttggtcatcg caccgcgacc
     6001 aaatgttgga gcaagacttg ctaccgttgg tccgtgtcag acacgcgcct ggttgtcgac
     6061 cgcgagcata cccagcgcgc gggagaattt ttgcgttaaa tagccggttt cgttactcga
     6121 cgcggaagca cacagcatcc cggtggagag ccagcggtta acagtcacgc cttcggcgtt
     6181 ttgcgcaatg tagttagcat cgcggtcttc tttcatcagt ttggcgatgc gatcaaacgc
     6241 ctcttcccaa ctgatttgct gccatttatc agaacctggc gcacggtatt ccggaaactt
     6301 cagacggctt tcggagtgga tgaaatccac caggccagcg cctttcggac aaagtgcacc
     6361 gcggttgacc gggtgatccg gatcgccttc gatatggaag atagatgctt tggcgttttt
     6421 tgctccgtca ccgaggctgt acatcaacag cccacagcct acggaacaat aggtgcaggt
     6481 attacgggtt tcgcgggtgc gcagcagttt atactgccgg gtttccgcga gtgctacgct
     6541 gggtgcaaaa cccagtgccg ctgccgtggt gcctgccata ccgccagcgc agatcttaaa
     6601 gaactgcctt ctgctgacct gcatggattg ctccttgttt cgacattgtc acgtcccatt
     6661 tacattcgct tgctgcgtgt gcagggagtg ggagttattt ttctttgcgg aaggggccgc
     6721 aaaggtccag aattggctca atttccctcc atccaggaag ggtttgtaac agaataccat
     6781 aatgttggtg tgtgtgttct tatctggtta agagaaagtg aaaaaaacac agcgaaaaga
     6841 aatcgaaaat gtgacaaata tcacaggtgt tcgtcaaatt gagttatggc ggcgtgatga
     6901 tttacaacac ccacggttag atgaggtcgc ggaagaagtt cccgttgcgc tggtctacaa
     6961 cggcatttcg catgtggtga tgatggcgtc gcccaaagac cttgagtact ttgcgctcgg
     7021 tttttcgctt tccgagggga ttatcgaaag tccgcgcgat atcttcggca tggatgtcgt
     7081 tccttcctgt aatggtcttg aagtacaaat tgagctttcc agccgccgct ttatggggtt
     7141 gaaggagcgc cgccgggcgc tggcgggacg tacgggctgt ggcgtatgcg gcgtggagca
     7201 acttaatgac atcggaaaac cggtgcagcc gctaccgttc acccagacgt ttgatctcaa
     7261 caaactggat gatgcattac gtcatctcaa cgattttcag ccagtggggc aactgactgg
     7321 ttgtactcac gccgctgcct ggatgttgcc atctggcgaa ctggtcggcg ggcatgaaga
     7381 cgtgggtcgc catgtggcgc tggacaaact gttaggccgc cggtcacaag aaggggaaag
     7441 ctggcagcaa ggtgcggtac tggtttccag tcgtgccagt tatgaaatgg tgcaaaagtc
     7501 ggcgatgtgc ggcgtagaga ttttgtttgc ggtgtctgcc gcgaccacgc ttgctgtaga
     7561 agtggctgag cgctgtaatc tgacactggt aggtttttgt aaaccgggtc gggcaacggt
     7621 ttatacccat ccgcagcgtt tgagcaatta attaaaataa gtcctgcgaa atatattaaa
     7681 ttgcaggact tattcatttc gtgaatttta ttattttatt tataaacaaa atgcgtgta
//
LOCUS       DAPHKZ010000178         7717 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.179, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000178 DAPHKZ010000000
VERSION     DAPHKZ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7717
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.179"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            151..5406
                     /locus_tag="RH288_004239"
     CDS             151..5406
                     /locus_tag="RH288_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter barrel domain-containing
                     lipoprotein"
                     /protein_id="HDV4033226.1"
                     /translation="MNRIYRVIWNCTLQVFQACSELTRRAGKTSTVNLRKSSGLTTKF
                     SRLTLGVLLALSGSASGASLEVDNDQITNIDTDVAYDAYLVGWYGTGVLNILAGGNAS
                     LTTITTSVIGANEDSEGTVNVLGGTWRLYDSGNNARPLNVGQSGTGTLNIKQKGHVDG
                     GYLRLGSSTGGVGTVNVEGEDSVLTTELFEIGSYGTGSLNITDKGYVTSSIVAILGYQ
                     AGSNGQVVVEKGGEWLIKNNDSSIEFQIGNQGTGEATIREGGLVTAENTIIGGNATGI
                     GTLNVQDQDSVITVRRLYNGYFGNGTVNISNNGLINNKEYSLVGVQDGSHGVVNVTDK
                     GHWNFLGTGEAFRYIYIGDAGDGELNVSSEGKVDSGIITAGMKETGTGNITVKDKNSV
                     ITNLGTNLGYDGHGEMNISNQGLVVSNGGSSLGYGETGVGNVSITTGGMWEVNKNVYT
                     TIGVAGVGNLNISDGGKFVSQNITFLGDKASGIGTLNLMDATSSFDTVGINVGNFGSG
                     IVNVSNGATLNSTGYGFIGGNASGKGIVNISTDSLWNLKTSSTNAQLLQVGVLGTGEL
                     NITTGGIVKARDTQIALNDKSKGDVRVDGQNSLLETFNMYVGTSGTGTLTLTNNGTLN
                     VEGGEVYLGVFEPAVGTLNIGAAHGEAAADAGFITNATKVEFGLGEGVFVFNHTNNSD
                     AGYQVDMLITGDDKDGKVIHDAGHTVFNAGNTYSGKTLVNDGLLTIASHTADGVTGMG
                     SSEVTIANPGTLDILASTNSAGDYTLTNALKGDGLMRVQLSSSDKMFGFTHATGTEFA
                     GVAQLKDSTFTLERDNTAALTHAMLQSDSENTTSVKVGEQSIGGLAMNGGTIIFDTDI
                     PAATLAEGYISVDTLVVGAGDYTWKGRNYQVNGTGDVLIDVPKPWNDPMANNPLTTLN
                     LLEHDDSHVGVQLVKAQTVIGSGGSLTLRDLQGDEVEADKTLHIAQNGTVVAEGDYGF
                     RLTTAPGNGLYVNYGLKALNIHGGQKLTLAEHGGAYGATADMSAKIGGEGDLAINTVR
                     QVSLSNGQNDYQGATYVQMGTLRTDADGALGNTRELNISNAAIVDLNGSTQTVETFTG
                     QMGSTVLFKEGALTVNKGGISQGELTGGGNLNVTGGTLAIEGLNARYNALTSISPNAE
                     VSLDNTQGLGRGNIANDGLLTLKNVTGELRNSISGKGIVSATARTDVELDGDNSRFVG
                     QFNIDTGSALSVNEQKNLGDASVINNGLLTISTERSWAMTHSISGSGDVTKLGTGILT
                     LNNDSAAYQGTTDIVGGEIAFGSDSAINMASQHINIHNSGVMSGNVTTAGDMNVMPGG
                     ALRVAKTTIGGNLENGGTVQMNSEGGKPGNVLTVNGNYTGNNGLMTFNATLGGDNSPT
                     DKMNVKGDTQGNTRVRVDNIGGVGAQTVNGIELIEVGGNSAGNFALTTGTVEAGAYVY
                     TLAKGKGNDEKNWYLTSKWDGVTPADTPDPINNPPVVDPEGPSVYRPEAGSYISNIAA
                     ANSLFSHRLHDRLGEPQYTDSLHSQGSASSMWMRHVGGHERSRAGDGQLNTQANRYVL
                     QLGGDLAQWSSNAQDRWHLGVMAGYANQHSNTQSNRVGYKSDGRISGYSAGLYATWYQ
                     NDANKTGAYVDSWALYNWFDNSVSSDNRSADDYDSRGVTASVEGGYTFEAGTFSGSEG
                     TLNTWYVQPQAQITWMGVKDSDHTRKDGTRIETEGDGNVQTRLGVKTYLNSHHQRDDG
                     KQREFQPYIEANWMGSFAGEGEILR"
     gene            complement(5476..6312)
                     /locus_tag="RH288_004240"
     CDS             complement(5476..6312)
                     /locus_tag="RH288_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="HDV4033227.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLK
                     PIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATE
                     IAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMM
                     SNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDP
                     RRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQT
                     SY"
     gene            complement(6312..7115)
                     /locus_tag="RH288_004241"
                     /note="aph(3'')-Ib"
     CDS             complement(6312..7115)
                     /locus_tag="RH288_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="HDV4033228.1"
                     /translation="MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASR
                     RGELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAW
                     PSMGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLL
                     ARVERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLA
                     LMIANAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
     gene            7401..>7717
                     /locus_tag="RH288_004242"
     CDS             7401..>7717
                     /locus_tag="RH288_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HDV4033229.1"
                     /translation="MCELDILHDSLYQFCPELHLKRLNSLTLACHALLDCKTLTLTEL
                     GRNLPTKARTKHNIKRIDRLLGNRHLHKERLAVYRWHASFICSGNTMPIVLVDWSDIR
                     EQKR"
BASE COUNT         2021 a         1807 c         2122 g         1767 t
ORIGIN      
        1 ttcgaaagca ttagcaaatt agccaaattg acaccttccc acctccaact aacactcaat
       61 acagacctct gacaatttaa taagtttcat ttttaatgtc tgacgactca tctctttcgt
      121 ggctgtattg tttgtatatg gagcgtttat atgaatagaa tctatcgcgt gatatggaat
      181 tgcactctac aggtatttca ggcctgctcg gaattaactc gcagggcagg taaaacatcg
      241 acggttaatt tgcgtaaatc ctctggactg acaacgaaat tcagtagatt gacgctgggt
      301 gttttgctgg cactaagcgg ttcagcgtct ggtgcaagtc tggaagttga taatgatcag
      361 attaccaata ttgatactga tgttgcttat gatgcctacc tggttggctg gtatggcact
      421 ggagtgctta atattttggc tggcggtaat gcctccttaa ccactattac taccagcgtc
      481 attggcgcta atgaggactc agagggcacc gttaatgttt tgggtggcac ctggcgattg
      541 tatgatagcg gaaataatgc aaggccttta aatgtgggtc aatccggaac ggggacgctg
      601 aatattaaac agaagggtca cgtcgatgga ggctatttaa gattaggttc ttcgacagga
      661 ggcgtcggga cggtcaatgt tgagggagag gactctgttc tgacgaccga attattcgaa
      721 ataggtagct atggcacagg ttcattaaat attacggata agggttacgt cacgagttca
      781 atcgtcgcca ttttaggcta tcaggcgggc agtaatggcc aggttgtcgt tgaaaagggt
      841 ggcgagtggc taataaaaaa taatgattcc tcaattgaat ttcaaattgg taatcaagga
      901 actggggagg cgactattcg cgaggggggg ctggttacgg ctgaaaatac gattatcggt
      961 ggcaatgcca ccggtatcgg aaccctgaat gtgcaggatc aagactctgt catcacggta
     1021 cgcagactct ataatggata tttcggtaat ggcacagtca atatttccaa taatggactg
     1081 attaataaca aagaatattc attggtgggc gttcaggacg gttcccacgg tgtcgtcaac
     1141 gtgaccgata aagggcattg gaatttcctc ggaacgggcg aagctttccg ctatatctat
     1201 atcggtgatg ctggcgacgg tgaacttaat gtctcgagtg aaggcaaagt agattcggga
     1261 attatcactg cggggatgaa agaaacaggc acaggcaaca ttactgttaa ggataagaac
     1321 tccgttatca ctaatctcgg aactaatctt ggttatgacg gccacggcga aatgaatatc
     1381 agtaatcagg ggcttgttgt cagcaacgga ggaagttcac tcggttatgg agaaaccggc
     1441 gtcgggaatg tcagcatcac cacgggggga atgtgggagg tcaataagaa tgtctatacc
     1501 accattggtg ttgcgggcgt cggaaacctc aatattagcg atggcggtaa gttcgtatcg
     1561 caaaatatta cttttttggg cgataaagca agcggtatcg gcacactgaa cctgatggat
     1621 gcgacatcat cgttcgatac tgtgggtatc aatgtcggta attttggtag cggtatcgta
     1681 aatgtcagta atggtgccac ccttaattca acgggctatg gatttatcgg aggaaatgcc
     1741 tccggtaagg ggatagttaa tatttcaacg gacagtctct ggaatttaaa gacatcatct
     1801 actaacgcac aattgctaca ggtcggtgta ttaggcacgg gtgaactgaa tattaccacc
     1861 ggaggtatag ttaaagcgcg tgatacacag atagctctca atgacaaaag taagggcgac
     1921 gtgagggtgg atgggcagaa ctctcttctt gaaacattca atatgtacgt agggacatct
     1981 ggtacgggta cgttaaccct gacgaataac ggtacgctga atgtcgaagg tggagaagtt
     2041 tacttaggtg tttttgagcc tgctgtagga acgctaaaca ttggtgctgc tcacggtgag
     2101 gcggcggcag atgccggatt tatcaccaat gcgacgaaag tggagtttgg tcttggcgaa
     2161 ggcgtttttg tctttaatca taccaataac agtgatgccg gctaccaggt cgatatgctg
     2221 attacaggtg acgataaaga cggaaaagtg atccatgatg caggccatac ggtgttcaat
     2281 gcagggaata cttatagcgg taaaacgctg gtcaatgacg gcctcctgac cattgcgtct
     2341 catacggcag atggggtaac gggcatgggg tcgagtgaag taaccattgc aaaccccggt
     2401 acgctcgaca ttctcgcatc aacgaacagt gcaggagatt acacgctgac caatgcgctc
     2461 aaaggcgatg gcttgatgcg agtgcagctg tcatcctccg acaagatgtt tggctttacc
     2521 catgcaacag ggactgaatt cgccggtgtt gcccaactga aagacagtac cttcactctg
     2581 gaacgcgaca acaccgctgc gcttactcac gcgatgttgc agtctgacag tgaaaatacc
     2641 acatcggtaa aagttggaga gcaatccatt ggtggactgg ccatgaatgg aggtaccatc
     2701 attttcgata cggatattcc tgctgcgacg ctcgcggagg gatatatcag cgtcgatacg
     2761 ctggttgtcg gcgcgggtga ctacacctgg aaaggccgta actatcaggt aaacgggacg
     2821 ggcgacgtgc ttatcgacgt gcctaaaccg tggaatgatc ccatggcgaa taaccctctg
     2881 acgacgctca atttgctgga acacgacgat agccatgtcg gcgttcaact ggtgaaggcg
     2941 caaacggtta ttgggtcggg tggctcatta acgttacgtg atttacaggg cgacgaggtg
     3001 gaagcggaca aaacgttaca cattgcgcaa aacggaacgg tggtcgccga gggtgattat
     3061 ggattccgcc tcacgaccgc accaggtaat ggtttgtacg ttaactatgg gctgaaagcg
     3121 ctgaacatcc atggtgggca aaagctgacg ttagccgaac atggcggagc ctatggcgca
     3181 acggccgata tgtcggcaaa aatcggtggt gaaggggatc tggcaatcaa tacggtgcga
     3241 caggtttcgc tttccaacgg tcagaacgac tatcaggggg caacctacgt tcagatgggg
     3301 acattacgta ccgatgcgga tggtgcactt ggcaacaccc gggaactgaa catcagcaac
     3361 gcggccatcg tcgatcttaa tggatcgacg cagacggtag agacattcac cgggcagatg
     3421 ggttcgactg ttttgttcaa agagggggcg ctgacggtaa ataaaggtgg gatcagtcag
     3481 ggtgaactga caggtggcgg aaacctgaat gttacagggg gaacgctggc tatcgagggg
     3541 cttaatgcac gctacaatgc gttaaccagc attagcccaa atgcggaagt cagcctcgat
     3601 aatactcagg ggttaggcag aggaaatatt gccaatgacg gtctgttaac gctaaaaaac
     3661 gtgactggcg aactgcgtaa tagcataagc gggaagggta tcgtgagcgc aaccgccagg
     3721 acagatgtag agttggatgg cgataatagc cgctttgtgg ggcaattcaa cattgataca
     3781 ggcagcgcgc tcagcgtcaa cgagcagaaa aacctgggtg atgcttccgt tatcaataat
     3841 ggcctgctca ccatctccac tgagcgtagc tgggcgatga cgcacagtat cagcggtagc
     3901 ggtgatgtga caaaactggg taccgggatc ctgactctta acaacgattc cgcggcgtat
     3961 cagggtacga cggatatcgt ggggggggaa attgctttcg gttccgactc tgccattaat
     4021 atggcaagtc aacacattaa tatccataac agcggtgtga tgtcgggaaa tgtcaccact
     4081 gcaggtgata tgaacgttat gcctgggggg gcactgcgtg tcgctaaaac cactatcggc
     4141 ggcaacctgg agaatggcgg cacggttcaa atgaatagcg aaggggggaa accggggaat
     4201 gtactgaccg ttaacggcaa ctataccgga aacaatggcc tgatgacgtt caacgcgacg
     4261 ctgggcggcg ataattcgcc caccgataag atgaacgtga aaggcgatac ccaagggaac
     4321 actcgcgttc gggttgataa cattggcggc gtcggtgcac aaacggtcaa cggtattgaa
     4381 ctcattgagg ttggcggtaa ttctgcaggt aacttcgcgc tgaccaccgg aactgtcgaa
     4441 gctggggctt acgtctacac gctggctaaa gggaagggga atgacgagaa aaactggtat
     4501 ctgaccagta aatgggacgg cgtaacgcca gcggatacac ccgatcccat caataatccc
     4561 cctgttgtgg atccggaagg cccatcagtt tatcgcccgg aggccggaag ctatatcagc
     4621 aacattgccg cagccaactc gctgtttagc catcgtttac acgaccgtct gggtgagccg
     4681 cagtatacag attcactgca ctctcagggg tcggcaagca gtatgtggat gcgtcatgtc
     4741 ggagggcacg aacgttcaag ggccggtgac ggtcagctaa atactcaggc taaccgctat
     4801 gtattgcagc taggcggcga tttggcgcag tggagtagca acgcgcagga tcgctggcat
     4861 cttggcgtga tggcaggcta cgccaatcag cacagtaata ctcagagtaa tcgtgtgggt
     4921 tataaatcgg atgggcgcat cagcggttac agcgctgggc tgtacgcgac ctggtatcag
     4981 aacgatgcga ataagaccgg cgcttatgtt gacagctggg cgctgtataa ctggtttgat
     5041 aacagcgtca gttccgataa ccgttctgct gacgactatg attctcgcgg tgtgacggcc
     5101 tctgttgagg gtgggtatac ctttgaagcg ggaacattta gcggcagcga agggacgctg
     5161 aatacctggt acgtccagcc acaggcgcaa atcacctgga tgggtgtgaa agattccgac
     5221 catacccgga aagacggaac gcgcattgaa acggaaggcg acggaaatgt gcaaacgcga
     5281 cttggggtga aaacctacct gaacagccat caccagcgtg acgatggtaa acagcgtgag
     5341 ttccagcctt acattgaagc gaactggatg gggtcgtttg cgggagaggg cgaaatccta
     5401 cgctaaggct ttggccaacg atattctccg gtaagattga tgtgttccca ggggatagga
     5461 gaagtcgctt gatatctagt atgacgtctg tcgcacctgc ttgatcgcgg ccgcgatagc
     5521 tagatcgcgt tgctcctctt ctccatccgc gttccaagct gcggaaaggc acccataagc
     5581 gtacgcctgg tcgagcaggc gacgcggatc gacgtccagc gcacgagaga atgcgtccgc
     5641 catctgtgca atgcgtctag gatcgagaca aaggtcgtct ctgtcagccg gatcgtagaa
     5701 catattggcg gcgccaaagc ccacttcacc gaccagaccg acgggatcta tcaccagcca
     5761 gccgcgactg gagaacatga tgttttcatg atgcagatcg ccatgtagcc cacgcagttc
     5821 cgaggcattg ctcatcattt gatcggctat aatcgccgcg tggacgtagt cagtttgaca
     5881 acctgcgttt tgatcatcgc gcgcccgctg aaacaaagct gcaaagcgat cccggatcgg
     5941 gagaagggca gaaggcaggg gttcctcaga tgcggcatac agcttcgcca ttagttccgc
     6001 tgcaatttcg gtcgcctggt agtcgccgtg ctcggcaacg atgtgagaga gcattcgctc
     6061 cccggcatat tcgagcaaca tcagattgtt ctcacgaccg agcaaccgga ctgctcccct
     6121 cccattgcgc cataccagat agtcggcccc gcgcagttca tcagcaatgt cttctatagg
     6181 tttcaatccc ttgacgattg caggagtccc gtctggcaat gaaactttcc aaacgaggct
     6241 ggaaaaggtg tccgcaatga gaacaggttg cgaaacgtgc caatgagcag gaaaaacagg
     6301 cggcatgaac atcaacccca agtcagaggg tccaatcgca gatagaaggc aaggcgttcg
     6361 cggtcggggg cttcgatccc caatacattg aataggacag cgaaggcgcg ctctgcttca
     6421 tctggcgctg cccagttctc ttcggcgtta gcaatcatga gtgccaaatc ggcatagcga
     6481 tctgctgttc cgagccgccc aaggtcgatc agacccgtgc attgaagagt tttagggtcc
     6541 accatgaagt tcggcatgca gggatcacca tggcaaacaa ccatatcggt gcgctcttgg
     6601 tcgagccgca ccggtagctc tcgttcgaca cgagccaaaa gatcgagctg cggcgtactc
     6661 ttgtcctcgt ccggtaagaa gtcgggattg acggcattgc gggacaccac atcaacggcg
     6721 cgtccgaaca ttcgcgacag cctgcgctca aacggacatt gatcaaccga taggctgtga
     6781 acagcgccaa gttgctgccc cattgacggc cacgctttga gcaaatccgc tccagacaga
     6841 tcagccgccg gtactcccgg aattgccgtt atcaccaagc atgcaccctc ctgttcctcc
     6901 tgccagttga tcacctcggg gcaagccaca cctcgacctt tgagccaaat gaggcggtca
     6961 cgctctccag cgagctcacc gcggcgggaa gcaggtgcga ttttcgcgaa ggcatgcccg
     7021 tcaccacgtc gaaaaacaaa atcaccagat tctccgcctc tgacaggcaa ccagtcagaa
     7081 tgcgattcac caaaaaaaat attagttcga ttcaatggag gttccttcag ttttctgatg
     7141 aagcgcggag gtggctcaac ctgcgaaaag aaacgagttg ctacgtaagt ccgagaacat
     7201 gctttccatg gtcttgcacc ggttgtgttc cggtctatct ctcattttaa gcggcttttt
     7261 tctcaaatgc caccggcgat ttccagccga gtgctgatga atcccctaat gatttttatc
     7321 aaaatcatta agttaaggta gatacacatc ttgtcatatg atcaaatggt ttcgccaaaa
     7381 atcaataatc agacaacaaa atgtgcgaac tcgatatttt acacgactct ctttaccaat
     7441 tctgccccga attacactta aaacgactca acagcttaac gttggcttgc cacgccttac
     7501 ttgactgtaa aactctcact cttaccgaac ttggccgtaa cctgccaacc aaagcgagaa
     7561 caaaacataa catcaaacga atcgaccgat tgttaggtaa tcgtcacctc cacaaagagc
     7621 gactcgctgt ataccgttgg catgctagct ttatctgttc gggcaatacg atgcccattg
     7681 tacttgttga ctggtctgat atccgtgagc aaaaacg
//
LOCUS       DAPHKZ010000179         7572 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.180, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000179 DAPHKZ010000000
VERSION     DAPHKZ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7572
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.180"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(132..365)
                     /locus_tag="RH288_004243"
     CDS             complement(132..365)
                     /locus_tag="RH288_004243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI family protein"
                     /protein_id="HDV4033230.1"
                     /translation="MRIEIMIDKEQKISQSTLDALESELYRNLRPLYPKTVIRIRKGS
                     SNGVELTGLQLDEERKQVMKIMQKVWEDDSWLH"
     gene            complement(376..564)
                     /locus_tag="RH288_004244"
     CDS             complement(376..564)
                     /locus_tag="RH288_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033231.1"
                     /translation="MQDYFLESLKLQRIDFFLKLVAASECSDEEKGLALQWVSELTDE
                     LMAKIRTHEYNRSMDVIS"
     gene            complement(717..3131)
                     /locus_tag="RH288_004245"
     CDS             complement(717..3131)
                     /locus_tag="RH288_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HDV4033232.1"
                     /translation="MSHADMNNCSGFNEAAAAFSWDSPKKAINPYLDPAEVAPVSALS
                     NLITLYAADNEQEQLRREALSDQVWERYFFNESRDPVQREMEQDKLISRAKLAHEQQR
                     FNPDMVILADVNAQPSHISKPLMQRIEYFSSLGRPKAYSRYLRETIKPCLERLEHVRE
                     SQLSTSFRFMASHEGLDGLLILPEMSQDQVKRLSTLVAAHMSMCLDAACGDLYATDDV
                     KPEEIRKTWEKVAAETLRLDVIPPAFEQLRRKRNRRKPVPYELIPGSLARMLCADWWY
                     RKLWKMRCEWREEQLRAVCLVSKKASPYVSYEAVMHKREQRRKSLEFFRSHELVNEDG
                     DTLDMEDVVNASSSNPAHRRNEMMVCVKGLELIAEMRGDCAVFYTITCPSRFHSTLNN
                     GRPNPTWTNTTVRQSSDYLVGMFAAFRKAMHKAGLRWYGVRVAEPHHDGTVHWHLLCF
                     MRKKDRRTITALLRKFAIREDREELGNNTGPRFKSELINPRKGTPTSYIAKYISKNID
                     GRGLAGEISKETGKSLRDNAEYVNAWASLHRVQQFRFFGIPGRQAYRELRLLAGQSAR
                     QQGDKKAGAPVLDNPRLDAILAAADAGCFATYIMKQGGVLVPRKYHLIRTAYEINEEP
                     TAYGDHGIRIYGIWSPIAEGKICTHAVKWKMVRKAVDVQEAAADQGACAPWTRGNNCP
                     LAENLYQQGKDKSADGDTRTDITRMDDKELHDYLHSMSKKERRELAARLRLVKPKRRK
                     DYKQRITDHQRLQLVYELKSRGFDGSEKEVDLLLRGGSIPSGAGLRIFYRNQRLQEDD
                     KWRNLY"
     gene            complement(3128..3985)
                     /locus_tag="RH288_004246"
     CDS             complement(3128..3985)
                     /locus_tag="RH288_004246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HDV4033233.1"
                     /translation="MSTILKWAGNKTAIMSELKKHLPAGPRLVEPFAGSCAVMMETDY
                     PSYLVADINPDLINLYKKVAADCEAFISRARALFEEANREVAYYNIRQEFNYSTEITD
                     FMKAVYFLYLNRHGYRGLCRYNKSGYFNIPYGNYKNPYFPEKEIRAFAEKAQRATFIC
                     ASFDETLAMLKAGDVVYCDPPYDGTFSGYHTDGFTEDDQYHLASVLEHRSSEGHPVIV
                     SNSDTSLIRSLYRNFTHHYIKAKRSIGVAAGESKSATEIIAVSGARCWVGFDPSRGVD
                     SSAVYGVRA"
     gene            complement(3982..4209)
                     /locus_tag="RH288_004247"
     CDS             complement(3982..4209)
                     /locus_tag="RH288_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HDV4033234.1"
                     /translation="MADAMDLVQQRVEEERQRHIRAARAKTPGVSRVLCIECEAPIPP
                     ARRRAIPGVQLCITCQEIAELKGKHYNGGAV"
     gene            complement(4209..4442)
                     /locus_tag="RH288_004248"
     CDS             complement(4209..4442)
                     /locus_tag="RH288_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 family protein"
                     /protein_id="HDV4033235.1"
                     /translation="MRNIEILMTKTGPDDAGLNILLTEARLEERRARAEAMAARLDSL
                     ACHISSRQLNHVEAAELLRVTAEAIQNEAQEIH"
     gene            complement(4510..4851)
                     /locus_tag="RH288_004249"
     CDS             complement(4510..4851)
                     /locus_tag="RH288_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5347 domain-containing protein"
                     /protein_id="HDV4033236.1"
                     /translation="MAIEGAAATVPLSPGERLNGLNHIAELRAKVFGLNIESELERFI
                     KDMRDPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVV
                     SLFPRRLTMPN"
     gene            complement(4815..5015)
                     /locus_tag="RH288_004250"
     CDS             complement(4815..5015)
                     /locus_tag="RH288_004250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2724 domain-containing protein"
                     /protein_id="HDV4033237.1"
                     /translation="MLTKEPSFASLLVKQSPAMHYGHGWIMGEDGKRWHPCRSQDELL
                     AELSTKKRGNKWLLKALRRLFH"
     gene            complement(5023..5532)
                     /locus_tag="RH288_004251"
     CDS             complement(5023..5532)
                     /locus_tag="RH288_004251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory CII family protein"
                     /protein_id="HDV4033238.1"
                     /translation="MFDYKISKHPHFDEACRAFALRHNMAKLAERSGMNVQTLRNKLN
                     PDQPHQLNAPDIWLLTDLTEDSTLVDGFLAQIHCLPCVPINEVAKEKLPHYVMSATAE
                     IGRVAAGAVSGDVKTSAGRRDAISSINSVTRLMALAAVSLQARLQVNPAMASAVDTVT
                     GLGASFGLL"
     gene            complement(5565..5807)
                     /locus_tag="RH288_004252"
     CDS             complement(5565..5807)
                     /locus_tag="RH288_004252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HDV4033239.1"
                     /translation="MSTDISIRVPKEMATPAEFAEWEGISRGSVYQKIHHGQLAKYMV
                     KKEKNKGRVSLRYLMYKTDQVRESLGHSNFRVIVGK"
     gene            5927..6559
                     /locus_tag="RH288_004253"
     CDS             5927..6559
                     /locus_tag="RH288_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein CI"
                     /protein_id="HDV4033240.1"
                     /translation="MIQVKVGENTGGREAIHRLMAAYDFKSRQQLCDHLGASKSTMAN
                     RYLRDSFPAEWVIQCALETGVSLLWLTTGQGEPGPNIEPKKNINSVNSSKVVPLSELV
                     SPEIDKATLNGGLLVDAGKAIIDSSILPSDSSNLLLVTTSGDSYLIDRNQTPPVNGMW
                     LVDIDGIKSIVKLTRLPGNKLVVHQDDSSFECGLDDIEVVGRALKIIKSL"
     gene            6561..>7572
                     /locus_tag="RH288_004254"
     CDS             6561..>7572
                     /locus_tag="RH288_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDV4033241.1"
                     /translation="MTIRKQPNGKWLCECYPNGRNGKRVRKQFATKGEAIAFESFTME
                     EVNKKPWLGEKDDRRRLSELIELWYSLYGQTLADPKRLMAKLRIICNGLGDPIASELT
                     AGDFTKYREARLKGDVRNEDGTLMSPVKPRTVNLEQRNLSSVFGTLKKLGHWSAPNPL
                     AGLPTFKIAEGELAFLTSEEIKRLLDACADSQNPSLLLIAKICLATGARWSEAENLQG
                     HQLSKYRITYTKTKGKKNRTVPISQDLYDELPKNRGKLFTPCRKAFERAVKRAGIELP
                     EGQCTHVLRHTFASHFMMNGGNILVLRDILGHADIKMTMIYAHFSPDHLEDAVTKNPL
                     CNL"
BASE COUNT         1928 a         1929 c         1746 g         1969 t
ORIGIN      
        1 agtgcagcat aggtctcgcc ctgatagata atcaaatgat tactgtcttt ttacttatgg
       61 ttaacgcctc tcaaggctcg cggttcaacc ttgctgacgc cagaagcagg ttcagacgcc
      121 agcaacgttt cttaatgcag ccagctgtcg tcttcccaca ccttctgcat aattttcatc
      181 acttgttttc tttcttcgtc cagttgcaat ccggtaagtt ccacaccgtt agagctacct
      241 ttgcggatac gaattaccgt tttgggatac agggggcgca gattgcggta aagctcggat
      301 tcaagggcgt ccagtgtaga ctggctaatc ttctgctctt tatcgatcat tatttcaatg
      361 cgcataaaag tcacctcagc tgatgacatc cattgagcgg ttgtattcgt gggttctgat
      421 ttttgccatg agttcatctg tcagttcaga aacccactgc agagccagcc ccttctcttc
      481 atcactacac tcactagccg ctacaagctt aagaaaaaaa tcaatgcgct ggagcttcaa
      541 agactccaaa aaatagtcct gcatctttcc tcctatgaca ccaaagcaat actgtataca
      601 taaccactgt ttatatttac agtatataat aatcttactg atgtaaaacg tttttttacg
      661 ctcatcagcc tgatatgcct ggtattatta agagcacgaa ttgttaaccc gcgtaattaa
      721 tacaggtttc gccacttatc atcttcctgc aaacgctggt tccgatagaa gatacgcagg
      781 cctgctcccg acggaatact gccgccgcga aggagtaaat cgacctcttt ctcgctgcca
      841 tcaaatcccc tggacttcag ttcatacacg agctgcagtc gctgatggtc tgtaattcgc
      901 tgtttgtagt ctttacgccg tttcggtttc accaggcgta accttgctgc cagttcccgg
      961 cgctcttttt tgctcatact gtgcaggtaa tcgtgcaact ccttgtcatc catgcgggtg
     1021 atatccgttc tggtatctcc atcagctgat ttgtctttcc cttgttggta caaattttca
     1081 gcaaggggac agttattgcc acgagtccaa ggggcgcaag cgccctggtc ggctgccgcc
     1141 tcctgaacgt caacggcctt acgaaccatt ttccacttca ccgcatgagt gcagatcttg
     1201 ccctctgcaa taggtgacca gatgccataa atacgaatac cgtgatcgcc atatgcggtc
     1261 ggttcttcgt tgatttcata agcagttctg atgaggtgat atttgcgggg aaccagtacg
     1321 ccgccctgct tcatgatgta ggtggcaaaa caaccagcat cagcagcagc caggattgca
     1381 tcaaggcgcg ggttatccag taccggcgca cctgcttttt tgtccccctg ttgccttgcc
     1441 gactgaccag ccagcaatcg cagttcacgg taagcctgac gccccggaat gccaaagaag
     1501 cggaattgct gaacacgatg cagagacgcc caggcattaa cgtattcagc gttatcacgc
     1561 agggatttac ccgtttcctt gctgatctcg ccagccagac cacgcccgtc aatgttctta
     1621 cttatgtatt tcgcgatgta gcttgttggc gtacctttgc gcgggtttat cagctcagac
     1681 ttaaagcgtg gtcccgtgtt attacccagc tcctcgcggt cttcacgaat ggcaaactta
     1741 cgcaacaaag cagtaatggt gcggcgatct tttttgcgca taaaacacaa caggtgccag
     1801 tgaactgtac cgtcatgatg cggctcagcc acccgcacgc cataccagcg caatccggct
     1861 ttgtgcatcg ccttacgaaa tgcagcaaac atgccgacca gataatcact gctttgtctt
     1921 accgtcgtat ttgtccaggt tgggttgggc ctgccgttat ttagcgtgga atggaaacgt
     1981 gacggacagg tgatggtgta gaaaacggcg cagtcaccgc gcatttccgc gataagctcc
     2041 agacctttaa cacagaccat catctcattg cggcgatgcg cagggttgct gctgctggcg
     2101 tttaccacat cttccatatc cagcgtgtcg ccgtcttcgt tcaccagttc atgagaacga
     2161 aaaaactcca gcgacttacg gcgctgctca cgtttatgca tcacggcttc atagctgaca
     2221 tagggggatg cttttttgct gaccaggcag acagcacgca actgctcttc ccgccattcg
     2281 caacgcatct tccataattt ccgataccac cagtcggcac acaacatacg cgccagcgaa
     2341 cccggaatga gttcataggg cacgggttta cggcggtttc ttttccgacg gagttgctca
     2401 aacgcaggcg gaataacatc cagacgcagg gtttccgctg ccaccttttc ccatgttttg
     2461 cggatttctt ctggcttaac gtcatcggtg gcatacaaat cgccacaagc tgcatcaaga
     2521 cacatgctca tatgcgcagc aacaagggtg gacaggcgtt tcacctgatc ctgactcatt
     2581 tcaggcagga tcagcaggcc gtccagccct tcatggcttg ccataaagcg aaaagaagtg
     2641 gatagctgac tctcgcgtac atgctccagt cgttccagac atggcttaat cgtctcacgc
     2701 aaatagcggg aataagcctt tggcctgccc aggctgctga agtattcaat acgttgcatc
     2761 agcggcttgc tgatatggga aggctgggcg ttgacgtccg ccagaatgac catgtctgga
     2821 ttaaaacgct gctgctcatg cgccagcttt gcccggctaa tgagcttatc ctgctccatt
     2881 tcgcgctgga caggatcacg ggattcatta aagaaataac gctcccagac ctgatcactc
     2941 agtgcctcgc ggcgcagttg ttcctgctcg ttatcggcag cgtacagagt gatcaggttt
     3001 gaaagcgcag aaaccggcgc aacttctgcc gggtccagat aagggttaat agcctttttc
     3061 gggctgtccc atgagaatgc tgcggcggcc tcgttaaagc cgctgcagtt gttcatatca
     3121 gcatggctca tgcacgcact ccgtacacgg cagaactatc cacgccacgc gaaggatcaa
     3181 atcccaccca gcagcgcgcc ccagaaacag cgatgatttc tgttgcagat ttactctcac
     3241 cagctgctac gccgatgctg cgttttgcct tgatgtagtg gtgagtaaaa ttgcgataca
     3301 gcgaacggat cagggatgtg tcactgttag aaacaatgac cggatgtcct tctgatgacc
     3361 gatgttcaag aacggatgcc aggtgatact ggtcatcttc agtgaagccg tcagtgtgat
     3421 aaccggaaaa cgtgccgtca tacggcggat cgcaatacac cacatccccc gccttcaaca
     3481 tcgccagcgt ttcatcaaag ctggcgcaga taaacgttgc ccgctgggct ttctctgcaa
     3541 atgcgcgaat ttctttttca gggaaatacg gatttttata attaccgtag ggaatgttga
     3601 aatacccgct cttgttatag cgacataacc cacggtaacc atgacgattg agatacagaa
     3661 aatataccgc tttcatgaaa tcagtaattt cagtggagta attaaactcc tgccttatgt
     3721 tgtaataagc cacctccctg tttgcttcct caaataaagc tctggcacga gatataaatg
     3781 cctcacaatc agcagcaacc tttttataga ggttgattaa atcaggatta atatccgcaa
     3841 caagatagct ggggtaatcc gtctccatca tcacagcaca ggaacccgcg aaaggttcaa
     3901 ccagtcgcgg gccagcagga aggtgttttt tcagttcgga cataatggcg gttttatttc
     3961 ccgcccattt caggatggtg ctcatacagc acctccgttg taatgtttgc ctttcagctc
     4021 tgcaatttcc tggcaggtaa tgcaaagctg cacacccgga atggcacggc ggcgtgctgg
     4081 cggaattggc gcttcacact caatgcaaag cacgcgagac acgcccggtg ttttggcacg
     4141 ggcagcacgg atatggcgct ggcgttcttc ttcaacgcgc tgctgtacga gatccattgc
     4201 atcagccatt agtggatctc ctgcgcttcg ttctggattg cttcagcagt cacacgcagc
     4261 agttctgccg cttccacgtg gtttagctga cgggatgaga tatgacacgc caggctatca
     4321 aggcgagctg ccattgcttc agcccttgcc cggcgttctt ccagacgagc ctctgtcagt
     4381 aaaatattaa gccctgcatc atccggtccg gttttagtca tgaggatttc aatattacgc
     4441 ataatcaatt ctcctgaatt tagataaagg gatgctcggc gggtttacgc cattaatttc
     4501 attagttggt taattcggca tggttagccg tctgggaaat aagctcacca ctgcacgaaa
     4561 atgattcatt gctttaatca actcccgctt ttcgtcagtg gtcagctcat tgatgctgat
     4621 gctatgacgt tcagccggaa tttttgccat aaagaatatg gctgccagtg ctcgtttatt
     4681 ttgttcgtta ttgatatccc gtggatcacg catatcttta ataaaccgct caagctctga
     4741 ctcaatattc aggccaaaaa ctttcgccct taattccgct atgtgattaa gtccattcag
     4801 gcgttcaccg gggcttaatg gaacagtcgc cgcagcgcct tcaatagcca tttgttcccc
     4861 cgttttttcg tagatagttc tgccagcaat tcatcttgtg aacggcacgg atgccagcgt
     4921 ttaccatcct cacccatgat ccagccgtga ccgtagtgca ttgccggact ttgttttacc
     4981 agcagcgatg caaatgatgg ttctttcgtc agcataagca cctcacagca aaccgaatga
     5041 agcaccgagg ccggttacag tatcaactgc acttgccatc gcaggattaa cctgtaaacg
     5101 ggcctgcaat gaaacagcag ctaacgccat cagtcgtgta acagagttaa tgctgctgat
     5161 agcatcacga cgacctgcac tggtttttac atcgccagat accgcacctg cagcaacacg
     5221 cccgatctct gcggttgcac tcatgacgta atgtggcagt ttctcttttg ccacctcatt
     5281 aatcggtaca catggcaggc agtgaatctg tgccagaaaa ccgtctacca gcgttgaatc
     5341 ttccgtcaga tcggtaagta gccagatatc tggcgcattg agctgatgcg gttgatctgg
     5401 gttgagtttg tttcgcagag tctggacatt cattcctgaa cgttctgcca gcttcgccat
     5461 attgtgacga agtgcaaaag ctctacaggc ttcatcaaaa tgcgggtgtt tggaaatctt
     5521 ataatcaaac atgctacccc cttagaaagt tctcataatt gaacttactt accaacaatg
     5581 acgcggaagt tggaatgacc gagggattca cggacctgat cggttttgta cattaaataa
     5641 cgcaggctta cgcggccttt gtttttttct ttcttgacca tgtatttagc aagctgacca
     5701 tgatgaattt tttgatacac agagccgcgg gagatacctt cccattccgc gaactctgca
     5761 ggcgtagcca tctcttttgg tacacgaatt gaaatatcag tgctcatagt gcagtatctc
     5821 ccgattaagg tttggtttac gtcgttttat ctcgttttac ttgattcaat atttgataca
     5881 tcgagatact acgatccaat atttgatacg tcaacaggat taaaaaatga tacaggtaaa
     5941 ggttggagag aatacagggg gaagagaggc tatccataga ctaatggcag cctatgattt
     6001 caagtccaga cagcaacttt gcgatcactt aggcgcatca aaaagcacca tggcaaacag
     6061 atacttaaga gatagttttc ctgcagagtg ggtgattcag tgcgccttgg aaacaggagt
     6121 ttctttactg tggctaacca ccggacaggg ggagccaggt ccaaacattg aacctaaaaa
     6181 aaatatcaat tccgtgaact ccagcaaggt tgtacctctt tctgaactag tatctcctga
     6241 aattgacaag gcgactctca acggtggttt attggtcgat gctggaaaag caatcattga
     6301 tagcagcata ctcccctcag actcaagcaa cctactgctg gtgactactt ctggtgattc
     6361 ttatttaata gatcgcaacc aaacaccacc agtaaatggt atgtggttag tcgatattga
     6421 cgggataaaa agcattgtta aattgactcg acttccggga aacaaattag tagtgcatca
     6481 ggatgattca tcgtttgagt gtggcctaga tgacattgag gtagtaggcc gcgcactgaa
     6541 aatcattaag agcctttgat atgaccatca gaaaacagcc gaacggaaaa tggttatgtg
     6601 agtgctatcc caatggacgc aatggtaagc gcgtgcgtaa gcaatttgct acgaaaggcg
     6661 aagccattgc ttttgaaagc ttcacaatgg aagaagtgaa taaaaaaccg tggttgggtg
     6721 aaaaggatga tcggcgacgc ctatcagaat taattgagct ttggtattcc ctgtatggtc
     6781 agacactcgc agaccccaag cgcctcatgg cgaaacttag aattatctgt aatggtctag
     6841 gcgaccccat cgcctcagaa ctgacagccg gtgactttac gaaataccgc gaagcacggt
     6901 taaaaggtga cgttcgtaac gaagacggca cactaatgtc gccagtaaaa ccacgcacgg
     6961 tgaatcttga gcaacgtaac ctatcatcgg ttttcggcac attgaaaaaa ctaggccact
     7021 ggtcagcacc aaatcctctc gccgggctgc caacatttaa aatcgctgag ggggaactgg
     7081 cgttcctgac ctcggaagaa attaaacgtc tgctagatgc ctgcgctgat tctcaaaacc
     7141 ccagtctgct tttgattgca aaaatatgcc tagccaccgg cgcacgctgg agtgaagctg
     7201 aaaacctgca gggccatcag ttatctaaat accgcatcac ttataccaag acgaagggta
     7261 agaaaaaccg caccgtgccg atatctcaag atctgtatga cgaactcccc aagaacagag
     7321 ggaagctatt caccccgtgc agaaaagcct ttgaacgagc agtaaagcga gctggcatcg
     7381 agctgccaga gggccaatgc actcacgtgc tacgtcatac attcgccagc cattttatga
     7441 tgaatggcgg aaacatactg gtgctgcgcg atattctggg ccatgccgat ataaaaatga
     7501 cgatgattta cgcccacttt tcgcccgatc accttgaaga tgcggtaact aaaaaccctt
     7561 tatgcaactt aa
//
LOCUS       DAPHKZ010000180         7417 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.181, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000180 DAPHKZ010000000
VERSION     DAPHKZ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7417
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.181"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..2293)
                     /locus_tag="RH288_004255"
     CDS             complement(<1..2293)
                     /locus_tag="RH288_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001486777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033242.1"
                     /translation="MLSKLFKSVNSLVDRELRHNLRMNSEYRKYRWNVFERLLAWCST
                     YYGRAMLILWVGAIMIVLAGLYLRPVLAPFGRQYFKGIEKLPDGLSDLLGGQLTIIGI
                     VFPLVVGLISVLFQKKSTREHIQSAYQLYSGYMFAGLSGLSLAAFILVSELLSARGDK
                     YLDICLVVVAIIWMIMNIGLSIWFFIQSLNVLDDRRRDRIMLKYFISKVVAQHIRTAM
                     VKNWLALPGRYINQMGRLNVSVDVYDSPEKEKSELLKLKLKMDECVRDIYTLPLLFLL
                     RRLKPVGTGPARIRVLPGWGIHNSEVVILATTGIRYNAIWEKLFKLCFIRGSKWEKTN
                     FLNFTRGFYGEIYDALDERNLGAFEEAADRLVSTFITLKRCFQYGDKNYIDDVSISFF
                     PQSLSQSFHNDFYRLAEEVVKTLDTTSTYFRKIIHLPQSFYRYRGEDRTGELQQALQS
                     QCDIWQILIDWNVGNKALSVNQKQRYVAMLQHFIGEWESWHMWLRLTFKNNVDTAGYT
                     EALVSHLFRSMEMLITAITSDDIDATDLSTDMFMLWLNQGQFHNHYHEEYLWHSLFLT
                     PDFLLHSVSDNCQSCILRGASYNEKAALSLTMRNVMTDLRLFLSAYMVRYLGQQKNVN
                     LLTVIKRLLSPSLVAPTGAYNTLPSAIVGQTDIIDVILRLTFCHADEHSNWFSRLSHM
                     VERLTRNNKGPVISGRIYMSSVDDLNTLYPAFADIAVMLSVSEQRISQKVVTAIGEGI
                     FSFSDKKNIVYTLKSLTKSTTEVA"
     gene            2973..4188
                     /locus_tag="RH288_004256"
                     /pseudo
     CDS             2973..4188
                     /locus_tag="RH288_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            5032..6009
                     /locus_tag="RH288_004257"
     CDS             5032..6009
                     /locus_tag="RH288_004257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDV4033243.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNT
                     LSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVE
                     LPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSA
                     YYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPA
                     PISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKLFCIHYRRPR
                     LKAPNDESKENPLPPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
     gene            complement(6288..7028)
                     /locus_tag="RH288_004258"
     CDS             complement(6288..7028)
                     /locus_tag="RH288_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDV4033244.1"
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAY
                     LLAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLDGVRPFVRILSEK
                     VRARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAV
                     RRAEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFAL
                     DMAATLAVPFTGDGRDAAEILRTLPPLK"
     gene            complement(7149..7409)
                     /locus_tag="RH288_004259"
                     /pseudo
     CDS             complement(7149..7409)
                     /locus_tag="RH288_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312821.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2030 a         1806 c         1685 g         1896 t
ORIGIN      
        1 ctgctacttc tgttgtgctt tttgtcagag atttcagcgt ataaacaata ttttttttat
       61 cagaaaatga aaaaatccct tcaccgattg cagtaaccac tttctggctg atacgttgtt
      121 cagatacaga cagcattacc gctatatcag caaatgcagg gtatagtgtg tttaaatcat
      181 caacactact catataaatc cgcccggaaa taaccgggcc tttgttgttt ctggtgagcc
      241 tctccaccat atgagacaaa cgtgaaaacc agttactgtg ctcgtctgca tggcagaaag
      301 tgagacgtaa tataacatca ataatatcag tctgacctac tattgccgaa ggtagtgtat
      361 tatatgcacc agttggggcg accagtgaag gagacagtaa ccgtttgatg acagtgagca
      421 aattgacatt tttttgttgt cccagatacc tcaccatata agctgacagg aacaggcgga
      481 gatcagtcat cacattacgc attgtcaggg ataatgcggc tttttcgtta tacgatgccc
      541 ccctcaatat gcaggactga cagttgtctg aaacagagtg caataaaaaa tctggcgtaa
      601 gaaaaaggct gtgccacaga tattcttcgt gataatgatt atgaaactgc ccctgattaa
      661 gccacagcat aaacatatca gtactcagat cagtggcatc aatatcatca gatgttattg
      721 ctgtaataag catttccata gagcgaaaca aatgtgatac aagggcctca gtatagccag
      781 cagtatcaac attattctta aacgtcagac gcaaccacat atgccagctt tcccactcgc
      841 cgataaaatg ttgcagcatt gcaacataac gttgcttctg gttcactgat aacgccttgt
      901 ttccaacatt ccagtcaatc agtatctgcc agatatcaca ctgggactga agagcctgtt
      961 gcaactctcc ggttctgtct tctccccgat accggtaaaa agactgagga agatgtatga
     1021 tctttcgaaa atacgtagat gtggtatcca gtgttttcac cacttcttct gcaagacggt
     1081 agaaatcatt atgaaaagac tggcttaaac tttgtggaaa aaatgaaatg gatacatcat
     1141 caatataatt tttatcacca tactggaaac atcttttcag tgtaataaag gtcgaaacaa
     1201 gtctgtctgc agcttcctca aacgccccca gatttcgttc atccagagca tcataaattt
     1261 ccccataaaa acctctggtg aaatttaaaa aatttgtttt ttcccatttg cttccacgga
     1321 taaaacagag cttaaacagc ttctcccaga tagcattata tctgataccg gttgtagcca
     1381 gaataaccac ttcgctgtta tgtatccccc acccgggtaa gactctgatt cttgcaggtc
     1441 ccgttccgac aggttttaat ctcctgagga gaaacaataa tggaagtgta tagatatctc
     1501 tcacacattc atccatttta agttttaact tcagaagctc agacttttcc ttctccggag
     1561 aatcataaac atcaacagag acattcagcc gtcccatttg gttaatatat ctcccaggaa
     1621 gagccaacca gttttttacc attgctgttc tgatatgttg cgccacgact tttgaaataa
     1681 aatacttaag cataattcga tcacgccggc gatcatccag aacattcagg ctctgaataa
     1741 aaaaccagat agacaaacca atattcatga tcatccagat tattgccact acaacaaggc
     1801 aaatatcaag gtatttatcc ccccgggcag acaaaagttc actcaccaga ataaatgcag
     1861 caagggaaag accgctcaga cctgcaaaca tgtatcctga gtaaagctga taggccgact
     1921 ggatatgctc acgtgtcgat tttttctgaa aaaggacgct gatcagaccg acaactaatg
     1981 gaaatacaat accaatgatg gttaattgtc cacccagcag atctgagagt ccatctggaa
     2041 gcttttcaat ccccttaaaa tactgcctgc caaatggagc caagaccggc ctcagataca
     2101 aaccagcaag tacaatcatt attgcaccaa cccagagaat caacatagcc cgcccatagt
     2161 atgtcgagca ccaggccagc aggcgctcaa aaacattcca gcggtatttt cgatattcag
     2221 aattcatacg taaattatgt ctgagctcac gatcaacaag actgttcacg cttttaaaca
     2281 gtttactcaa cataagtaac cttcataacc ggatttatcc tctgatttca ctgccagaat
     2341 gatacgttga tttacctatt tttataactg tgaatcaagc tcagctcagt tccagactcc
     2401 gacaagccag acagatattg attccagact ttgttataag atattgacta gctcactctt
     2461 aagaactaat tttaaaattt tgttgataac atctttcagc ctctctggtt ttctaggccc
     2521 aagccagcaa cgtcagcccc cacagctcct aagctcctat agttggatta atatgagcga
     2581 agctgtcgaa ctagcgttac cggacgaaga agttcttctg ttcaggaccg caaagacatg
     2641 gaaacgatgt taggctctta ttgtgttaac cacgaaatta atccagcatc gttgtccggc
     2701 aacctctgtt ccaacttttc cctgtcatgc tggatcaggt gtcttagctg agccactgtt
     2761 actggtactg tccacctcca ccgcataaca ggccgaagcc acaacattca tagaaaatgt
     2821 tgttttttat ctcccttctc gccgcctctg tcaaagccaa gggtcatgta caggcaataa
     2881 agaaccttta ggggaatgtc acgaacggtg caaaaatggt tcttccgcaa cttgggggaa
     2941 gggaagaaaa aggatctaag ctgttttaag ttatgggtaa cgcaatgcac tctcttaaga
     3001 cacttctaca gttaccttgc agatggcaat gcagtcgaca aataattagc tctgacggta
     3061 taaccctcca tctccgcgga aaacgcaaaa cagcacaatg ccctgaatgc tttaagcgta
     3121 gcgattctgt tcatagttgt cgccggctgg atacagcatc taccctgtgc aggccagacg
     3181 ctatggcttg tattttccgt ccgccactag tactgccgta acccagcttg ttcacgtaaa
     3241 atttttgccg agtcgcttgc tcccttcgcc ggttcacacc agcagtcttc actggcatta
     3301 caaaatttgc aacgtcaact gggattaata gccggaggtg aggccggaaa acgagcagca
     3361 acggcagtgg gtctccgttg cagtgcagat actcttcttc gcagggttat caataccccg
     3421 gagacgagac tgtcaggcgc gctccatgtc agtattaatg agtggaggtg gccatcgggg
     3481 ccaccgttac ggtacgttaa ttgtcaatct tgatactcac cgtcccctcg ccctgcttcc
     3541 cggccgtgag cagtgtacac tggccaccag gttcagaaaa tatccggaaa tacaggttgt
     3601 ctcgcgtgat cgtagtggag tctatgcgac agcagcatgt gagggtgcac ctcaggccag
     3661 gcaggtggct gatcgatggc atctgctaaa taatattgac gatgcgcctg aacgaatgat
     3721 gtacagacat atacctctga tactcttgtt gccccaaaga aatcacctga gccataactg
     3781 cctgtgcctg cagcatcgct ccgttgtccg gaatgcctta aacagcaaac cagcaaaaaa
     3841 cggcatcagc gttggacaaa ggttatggcc ctgcataaca agggatgtag tttcagggaa
     3901 atatcccgta ttacaagcct gccgcgtgtg acagtcagtc gctgggtgcg ttcaggaaca
     3961 ttccctgaaa tgtcaaccat gcctccaaag cgagggcttc tggcctcatt tagagagtgg
     4021 ttaaaagagc aacgagaaag tggtaattat aacgccagcc ggatatggcg gcccggggtt
     4081 tacaggcagt gaaaccatcg tcagggatgc tgttgccaaa tggcgtaaag gttggctcca
     4141 accggttact actgccgcta gacttccgta agccgctggt tgatgcccta gagaagtatg
     4201 tacaactggg ccagagtaaa gcacaccttg ctgtcacggg tgaccggtca gatacatgaa
     4261 tctgcagata gatatatcat cagagactcc cttttatttc gcgaataagt gtctgtaata
     4321 acgccgatgc caaccagttc acaacttttc cattgaagca gctcaccacc ggtgataacc
     4381 agactttacc tgtagtctgt atacacgatc cctgtggtat tgaaataaac atatgaagtg
     4441 tacttcggat atgaccgtat gttcaggaag tacggcagat tgagtcgaaa attacctgta
     4501 aagacagact tcagaaaaaa cagtgctcgc cgcagaccgg tgaccgggcg aagcccgcga
     4561 accggcgagg aagcgcaatg gatctgtagt tacagtgagc aggtacgccc tgaagccttc
     4621 ataatcggta gtgtgtgttg tttttctgga atgatttatc cacatatcca ggggttcgat
     4681 ccagtaaaca gatccatgaa tgatcaacaa aggatccatt aaagatcccc atatcgctgt
     4741 aaaccttgtc actcatgggc cgggaccacg atcacataag ctgtggcatg ttactgataa
     4801 actgtaacat gctaatgata agctgtattc agtaatccat atactgaagt aagttaatga
     4861 cataaactat ggtcagtacg ccagactcag ttgttaaata caggctgcag gtttttcttc
     4921 agtcagttga cggggttctg acacacgatt ttctgtttat tcttttactg tccacaggca
     4981 ggaggctttc tggaaaacga aaattcagac atcaaaaaac tgttcggcga ggtggataag
     5041 tcgtccggtg aactggtgac actgacacca aacaataaca acaccgtaca acctgtggcg
     5101 ctgatgcgtc tgggcgtttt tgtaccgacc cttaaatcac tgaagaacag taaaaaaaat
     5161 acactgtcac gtactgatgc cacggaagag ctgacacgtc tttccctggc ccgtgctgag
     5221 ggattcgata aggttgagat cactggcccc cgcctggata tggataacga tttcaagacc
     5281 tgggtgggga tcattcattc ctttgcccgc cataacgtga ttggtgacaa agttgaactg
     5341 ccttttgttg agtttgcaaa actgtgtggt ataccttcaa gccagtcatc ccgcaggcta
     5401 cgtgagcgca tcagcccttc cctgaagcgc attgccggta ccgtgatctc gttttcccgt
     5461 accgatgaga agcacacccg ggaatacatc acccatctgg tacagtcagc ctactacgat
     5521 actgaacggg atattgttca gttacaggct gatccccgcc tttttgaact gtaccagttt
     5581 gacagaaagg tccttcttca gcttaaggcg attaatgccc tgaagcgacg ggagtccgcc
     5641 caggcacttt acacctttat agagagcctg ccccgggatc cggcaccgat atcgctggcg
     5701 cggctgcgtg cacgcctcaa tctgaagtct cctgtatttt cccagaacca gacggtcaga
     5761 cgggcaatgg agcagctgcg cgagattgga tatcttgatt acacggagat ccagcggggg
     5821 cggacaaaac tcttctgcat tcactaccgg cgtccccggt taaaagcacc gaatgatgag
     5881 agtaaggaaa atccgttgcc accttcacct gcggaaaaag tcagtccgga gatggcggag
     5941 aagcttgccc tgcttgagaa actgggcatc acgctggatg acctggaaaa actcttcaaa
     6001 tcccgctgaa cataaactgt agtcagtgaa gagtgctcct ttactgacta cagcttatat
     6061 tatcaggtgc agtgagtggt ctgctcactg cagtttatat tcagtttcct gcagtgctgt
     6121 ctgtagctga gctgccatct gcctgtccct tacgtaagtg atcccgtaac ctgatgctga
     6181 ggcattgctc ccttcataaa acatgactta ctcactacag cttatctacc tgctccagct
     6241 tatgttatgt ctgttctgct gaccactgct tatataagga agtgccgtta cttcagggga
     6301 ggcagtgtac gcaggatctc cgcagcatcc cgcccgtcac ctgtgaaagg cactgccagc
     6361 gtggcagcca tatccagtgc aaacactctg gtataaacct ccatagaacg tggatccctg
     6421 tgaccagcca gtgcctggat gactttccgg ggctggcggt gatagagcat gtgcatgata
     6481 tagctgtgcc ggaaggtgtg tggtgtgacc ggaatcgaaa agtgtactcc gtcagcttcg
     6541 gcccgtctga cagcctgctt cagccagttg cgcatggttt cgtcggtcac ggcccataat
     6601 ggttcacgac gacggggccg ggtggtgatc atccagcttt ccatctgcct gacatagctt
     6661 atatccgtca gcggaaccag gcggacttca tcttttggcg ggcgtccgcg tcgcgcacgc
     6721 actttttcgg acaggatccg cacaaacggt cttactccat ccaggtcaaa tgattccggt
     6781 gtcagcatcc gggcttcgcc aatacgcatt ccggtattcc agagggtggc gaacagcata
     6841 tggtgacgct gatccggcat atagaaaaga agggcactca cttccggggc cagcaggtag
     6901 gccggtgtgg cccctgtgga agtggccatt cttctcaggg agagcgctgt tgcaaaatcc
     6961 acccccggcg caatgggtaa cagggagacg cgttctggtg aattctgcag gggaatgaca
     7021 ttgttcatga gttatttttc acgtagcaca cgcactgttt atggatacag gtattctgac
     7081 ctgaacgccc ggatccttcc acgacaataa atcgcagcgc gcggatcctt ttgtttgatt
     7141 atcacgcatt attgcgggta aaaccaaata cgtaaaggcg cattttgccg ctgggatccc
     7201 gtcttaagcc agtcatggtg cgggctgagg gctggtttac cgtttttggg agaattgggg
     7261 taatgccagg atgaatggga tcggagaaaa cagagaaagg gaacagaaag ggagaaggtg
     7321 caccacgtgt attctggccc gggacgtcac cgtccccctg acagtttgac tttacacagg
     7381 aaggttgcag actcagcata atgactgatt tatatgc
//
LOCUS       DAPHKZ010000181         7289 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.182, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000181 DAPHKZ010000000
VERSION     DAPHKZ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7289
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.182"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..496
                     /gene="cni"
                     /locus_tag="RH288_004260"
     CDS             <1..496
                     /gene="cni"
                     /locus_tag="RH288_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_061352107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="colicin N immunity protein"
                     /protein_id="HDV4033245.1"
                     /translation="KKISFSLLLLLSPFALIFFSYNNAPIPLLEKIIAYLSLPGFHSS
                     NNPPLSEAFNLYVHTAPLAAISLFIFTHKELELKPKSSSLRALKILTPFTILYISMIY
                     CFLLTDTELTLSSKTFVLMSKNDLFLSFFYITLYIGIYIFTYLYLWFFIGTYKLFTRG
                     GILP"
     gene            complement(505..1668)
                     /gene="cna"
                     /locus_tag="RH288_004261"
     CDS             complement(505..1668)
                     /gene="cna"
                     /locus_tag="RH288_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin colicin N"
                     /protein_id="HDV4033246.1"
                     /translation="MGSNGADNAHNNAFGGGKNPGIGNTSGAGSNGSASSNRGNSNGW
                     SWSNKPHKNDGFHSDGSYHITFHGDNNSKPKPGGNSGNRGNNGDGSSAKAGEITITPD
                     NSKPGRYISSNPEYSLLAKLIDAESIKGTEVYTFHTRKGQYVKVTVPDSNIDKMRVDY
                     VNWKGPKYNNKLVKRFVSQFLLFRKEEKEKNEKEALLKASELVSGMGDKLGEYLGEKY
                     KNVAKEVAGDIKNFHGRNIRSYNEAMASLNKVLANPKMKVNKSDKDAIVNAWKQVNAQ
                     DMANKIGNLGKAFKVADLAIKVEKIREKSIEGYNTGNWGPLLLEVESWIIGGVVAGVA
                     ISLFGAVLSFLPISGLAVTVLGVIGIMTISYLSSFIDANRVSNINNIISSVIR"
     gene            1928..2365
                     /locus_tag="RH288_004262"
     CDS             1928..2365
                     /locus_tag="RH288_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="HDV4033247.1"
                     /translation="MGHCNFMAWHTLRDALKMTGRSRSQFYRDMRSGLVSYRTSQDGR
                     REFETSELIRAYGELKQNETQERHTVGQAENPHDQQTERILRELNELKQYLTLMLEDK
                     QAQDMDRRHQEAEREQLQNEIAQLRQALEQEKKRGFWSRLFGH"
     gene            2446..2874
                     /locus_tag="RH288_004263"
     CDS             2446..2874
                     /locus_tag="RH288_004263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="HDV4033248.1"
                     /translation="MKRSGGTRYLYLISLITVAAALTACTPKGSVEQHTRHYVYASDD
                     RSDPNFYTNKADTTRMMIPFFQQFREMGEKDKAAGVSAETAQQRIKEFHSEKFLQSLR
                     STTTFAGRKYMNSDMPSPEKMKLLADTISAVYLDGYEGRQ"
     gene            2974..3276
                     /locus_tag="RH288_004264"
     CDS             2974..3276
                     /locus_tag="RH288_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033249.1"
                     /translation="MLKTVRSCLLSALLTHLFFGNIAVAKENLSDDKVKQAIIDESIA
                     AYPGTCACPFNSARNGSSCGRRSAWSKAGGYSPICYKKEVTKEMIKDWRASHSNNN"
     gene            3368..3682
                     /locus_tag="RH288_004265"
     CDS             3368..3682
                     /locus_tag="RH288_004265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033250.1"
                     /translation="MSNNYDLIAKAIKEKLQVTAYYQGFYREMCPHALGSKKGRKQAL
                     FYQFGGESSKGTVTPGSTFNWRCIPIDGLTEVTLQSGQWYTAENHSQAQTCVDQIDIE
                     VQ"
     gene            complement(4062..4295)
                     /locus_tag="RH288_004266"
     CDS             complement(4062..4295)
                     /locus_tag="RH288_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="HDV4033251.1"
                     /translation="MTELEIHLLNALEQLQQDYMQRLSEWESAFVELQKMFSLTQRDN
                     AMLNERVMQLSQQVQHLSEQTERLSQLYSENWR"
     gene            complement(4302..4820)
                     /locus_tag="RH288_004267"
     CDS             complement(4302..4820)
                     /locus_tag="RH288_004267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001447511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="HDV4033252.1"
                     /translation="MSNLLQTGAEFEKKLKERAESTEKMLNDEFRKLGESVSEAVTSN
                     ETKIRDAIALFTASTEKSLEKHREGVKEAMMQHRKDVLKLAGNTGMMLLGIVFLLFTA
                     SGGTLWYLGGRIQTNLEEIRKQEETLQKLNAKTWGVEFVQDGNRKFLVLPYGKSAEVI
                     PFQGKEWVHLKE"
     gene            complement(4798..5556)
                     /locus_tag="RH288_004268"
                     /pseudo
     CDS             complement(4798..5556)
                     /locus_tag="RH288_004268"
                     /inference="COORDINATES: protein motif:HMM:NF015397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5498..5821)
                     /locus_tag="RH288_004269"
     CDS             complement(5498..5821)
                     /locus_tag="RH288_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDV4033253.1"
                     /translation="MLTIRVTDDEHARLLERCEGKQLAVWMRRVCLGEPVARSGRLPT
                     LAPPLLRQLAAIGNNLNQTARKVNSGQWSSGDRVQVVAALMAIGDELRRLRLAVREQG
                     ARDDS"
     gene            5885..6076
                     /locus_tag="RH288_004270"
     CDS             5885..6076
                     /locus_tag="RH288_004270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="HDV4033254.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDADEQADICESLHDH
                     ADELYRSCLARFGDDGENL"
     gene            complement(7096..7233)
                     /locus_tag="RH288_004271"
     CDS             complement(7096..7233)
                     /locus_tag="RH288_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="HDV4033255.1"
                     /translation="MCGKILLILFFIMTLSACQVNHIRDVKGGTVAPSSSSRLTGVEI
                     K"
BASE COUNT         1935 a         1961 c         1492 g         1901 t
ORIGIN      
        1 aaaaaaaata tcattcagtc ttctgctctt actttcccca ttcgcattaa tatttttcag
       61 ttataataat gcaccaatac cactccttga aaaaatcatc gcatacctat ccctaccagg
      121 atttcattca tcaaacaacc cgcccctaag cgaagcattc aatctctatg ttcatacagc
      181 ccctttagct gcaatcagct tattcatatt cacacacaaa gaattagagt taaaaccaaa
      241 gtcatcatct ctgcgggcgc taaagatatt aactcctttc actattcttt atatatccat
      301 gatatactgt ttcttgctaa ctgacacaga actaaccttg tcatcaaaaa catttgtatt
      361 aatgtcaaaa aatgacctgt ttttgtcttt cttctatata acactataca ttgggatata
      421 tatattcaca tatttatacc tttggttctt tataggaaca tataaactat ttaccagggg
      481 aggtatactc ccctgacact catgtcatcg aataacacta gatataatgt tatttatatt
      541 cgaaactcga tttgcatcaa tgaaagatga caagtaacta atcgtcatta ttcctattac
      601 ccccaacaca gtaacagcaa gtcctgagat tgggagaaaa ctcaacacag ccccaaacaa
      661 actaatagca actccagcaa caacgccccc gatgatccat gattcaacct ccagcaggag
      721 aggtccccag ttgccagtat tgtatccctc aatacttttt tccctaattt tctcaacctt
      781 tatagctaaa tcagcaacct taaatgcctt gccaagatta ccaatcttat tagccatgtc
      841 ctgagcatta acctgtttcc aggcattcac aatggcatcc ttatcagatt tgtttacttt
      901 catctttgga tttgctaaca ctttattcag tgaagccatt gcttcattat agctacgaat
      961 attacggcca tgaaagtttt taatatcacc ggcaacttcc ttagctacat ttttatattt
     1021 ttctccaaga tactcgccaa gtttatcccc catgccagac acaagttcac tagcctttag
     1081 caaggcttct ttttcatttt tttctttttc ttccttccta aataataaaa actggctcac
     1141 aaacctcttc acaagtttat tgttatattt cggtcccttc cagttcacat aatcaactct
     1201 cattttatca atattactat ctggaacagt aaccttgaca tactgacctt ttctggtgtg
     1261 aaaagtatat acctctgtac ctttaattga ttccgcatca attaattttg ctaacaatga
     1321 atattctgga tttgacgaaa tataacgacc aggtttcgag ttgtcaggtg taattgttat
     1381 ctctccagcc ttagcactcg atccatcacc attattacct ctatttccac tattcccacc
     1441 aggtttaggc tttgaattat tgtccccatg aaatgtaata tggtaagaac catcactgtg
     1501 gaagccatca tttttatgag gcttattact ccatgaccat ccattggaat ttcctcggtt
     1561 acttgatgcg ctaccattac ttccagcgcc actggtatta ccaatgcccg gatttttccc
     1621 tccaccaaaa gcattgttat gtgcgttatc tgcgccatta ctacccataa taaacccctc
     1681 tttgactttt aaaacaaacc attaaaaaca aatactgtac atatgaccac tggttttatg
     1741 tacagcgtaa aagctacgcc gctgcatttt ccctgtcaag actgtggact tccatttttg
     1801 tgaaaacgat caaaaaaaca gtctctcaca ccacgcgcta ttcccgccgg ataccacaaa
     1861 aaccggcgca aacattaccg ttctcagacc tcattatgtt ttactgaaac catgagatga
     1921 gacacctatg ggacactgta actttatggc atggcacaca ctccgggacg cactgaaaat
     1981 gactggaaga tcgcgttcac agttttaccg tgatatgcgc tcaggtcttg tcagttaccg
     2041 taccagccag gacggacgaa gggagtttga aaccagtgaa ctgatccggg catacggcga
     2101 attaaagcaa aatgagacac aagaaaggca cactgtggga caggcagaaa atccacatga
     2161 tcagcagaca gaacgcattc tccgggaact gaatgagctg aaacaatacc tgacgctgat
     2221 gcttgaggat aaacaggcac aggatatgga tcgcaggcac caggaagcag aacgggaaca
     2281 gttacagaat gagatagccc agctcaggca ggcactggaa caggaaaaga aacggggatt
     2341 ctggtccaga ctcttcggtc actgaactcg gtcagaggct gatgataaga tagtcttcgg
     2401 ataataactc accgagaata aatactttaa ggtaaggaga cacgtatgaa acgttctggt
     2461 ggcacacgct atctgtatct tatatccctg ataactgtgg ctgcagccct cacggcctgt
     2521 accccgaaag gcagtgtgga acaacatacc cgacattatg tgtacgcttc cgatgaccgt
     2581 tctgacccta acttctacac caacaaggcc gacaccacac ggatgatgat tccgttcttt
     2641 cagcagttca gggagatggg ggagaaagac aaagcagccg gagtatcagc agaaacggca
     2701 cagcaacgca taaaagaatt ccactcagaa aaatttcttc agtctctcag aagcacaact
     2761 acctttgcgg gcagaaaata catgaatagc gatatgccat caccggaaaa aatgaagctg
     2821 ctggctgaca cgatttctgc ggtttatctc gatggctacg agggcagaca gtaagtggat
     2881 ttaccataat cccttaacaa caagaagcga tttaagttgt ttttttgtac aaaaatgcaa
     2941 ttctcctagg attattcctc ggagactatt caaatgctta agacagtacg ttcgtgtctg
     3001 ttatcagctt tactgacaca tctttttttc ggcaatatcg ctgtggcgaa agaaaatcta
     3061 tcagatgaca aagtaaagca ggcgattatt gacgagtcga tagcagccta tcccggaaca
     3121 tgtgcatgtc cgtttaacag cgcaagaaat ggcagctcgt gcggcaggcg cagcgcctgg
     3181 agcaaagcag gaggttattc gccaatctgc tacaaaaaag aggtaacaaa agaaatgata
     3241 aaagattggc gagcttctca ctcaaataac aactgacttc tatttttata actttctgtt
     3301 tacattacat ttctgataaa tacatatatt tccaacagga aatcatactc tgggagattg
     3361 aagctaagtg tctaataatt atgatttaat tgccaaggca atcaaagaaa agttgcaagt
     3421 aacagcatat taccaaggtt tttaccgcga gatgtgccct catgcgctag gttcaaaaaa
     3481 aggacgaaaa caggctcttt tctatcagtt tggcggtgaa agcagtaaag gtactgtgac
     3541 acctggttcc acattcaact ggcgctgcat tcctatagat ggtctaactg aggtcacctt
     3601 acaatcaggc cagtggtaca cagcagaaaa tcacagccaa gcacagactt gtgttgatca
     3661 gatcgatatt gaagttcaat aaagcctgta ttcgtaccct cataaagctg ccattagtgg
     3721 cagctttatg tttatgacaa ccatcagcat ttaacataaa gccctgattg tacgcaccgc
     3781 taaaacgcgt tcagcgcgat cacggcagca aacaggtaaa aatggcaaca aaccacccga
     3841 aaaactgccg cgatcgcgcc tgataaattt taaccgtatg aatacctatg caaccagatg
     3901 gtacaggcca cattcccccc acttaatcca ctgaagctgc catttttcat ggtttcacca
     3961 tcccagcgaa gggccatcca gcgtgcgttc ctgtatttcc ggctgacgct cccgttccag
     4021 ggataacaca tgttcgcgct cctgtatcaa ccgttcctct cttatctcca gttctcgctg
     4081 tataactggc tcaagcgttc tgtctgctcg ctcaagtgct gcacctgctg actcaactgc
     4141 atgacccgct cgttcagcat cgcgttgtcc cgttgcgtaa gcgaaaacat cttctgcaat
     4201 tccacgaagg cgctctccca ttcgctcagc cgctgcatat agtcctgttg cagctgctct
     4261 aaggcgttca gcaaatgtat ttccagctct gtcactctgt gtcactcctt cagatgtacc
     4321 cactctttcc cctgaaaggg aatcacctcc gctgatttcc cgtacggaag gacaaggaat
     4381 ttcctgttcc cgtcctgcac aaactccacg ccccatgtct tcgcgttcag tttctgcaat
     4441 gtctcttcct gcttcctgat ttcttccagg ttcgtctgta tccgtccgcc aagataccag
     4501 agcgtcccgc cactcgcggt aaacaggaga aagactatcc ccagtaacat catgcccgta
     4561 ttccctgcca gctttaacac gtccttcctg tgctgcatca tcgcctcttt caccccttcc
     4621 cggtgttttt ccagcgattt ctctgtcgag gctgtgaaca gggctatagc gtctctgatt
     4681 ttcgtctcgt ttgaggtcac agcctcgctg acagactcgc cgagcttcct gaactcgtcg
     4741 ttcagcattt tctctgtaga ttcggctctc tctttcagct ttttctcgaa ctccgcgccc
     4801 gtctgtaaaa gattgctcat aaaatgctcc tttcagcctg atattcctcc cgccgttcgg
     4861 gtctgcaatg ctgatactgc ttcgcgtcac cctgaccact tcaagccccg cctctgtgag
     4921 cgcctgaatc acatcctgac ggccttttat ctctccggca tggtaaagtg cgtctatacc
     4981 gcgtgtaacg ctctcagcaa gtgcctgttt cgtttccggc aggttatcag gaagggtcag
     5041 cgtccggcgg ttctccgggg cgttggggtc atgcagtccg taatggtgat tcaccagcgt
     5101 ctgccaggca tcaattctcg gcctgtctgc gcggtcgtag tacggctgga gacgttttcc
     5161 ggtctgtagc tccatgttcg gaatgacaaa attcagctca agccgtccct tgtcctggtg
     5221 ctccacccac aggatgctgt actgattttt ttcgagaccg ggcatcagta cacgctcaaa
     5281 gctcgccatc actttttcac gtcctcccgg cggcagttcc ttctccgcga acgacagaac
     5341 accggacgtg tatttcttcg caaatggcgt ggcatcgatg agttcccgga cttcttccgg
     5401 attaccctga agcaccgttg cgccttcgcg gttacgctcc ctccccagca ggtaatcaac
     5461 cggaccactg ccaccacctt ttcccctggc atgaaattta actatcatcc cgcgccccct
     5521 gttccctgac ggccagacgc agccggcgca gctcatcccc gatggccatc agtgcggcca
     5581 ccacctgaac ccggtcaccg gaagaccact gcccgctgtt caccttacgg gctgtctgat
     5641 tcaggttatt tccgatggcg gccagctgac gcagtaacgg cggtgccagt gtcggcagcc
     5701 tcccggaacg ggcaaccggc tcccccaggc agacccgccg catccatacc gccagttgtt
     5761 taccctcaca gcgttcaagt aaccgggcat gttcatcatc agtaacccgt atcgtgagca
     5821 tcctctcgcg tttcatcggt atcattaccc catgaacaga aatccccctt acacggaggc
     5881 atcagtgact aaacaggaaa aaacagccct taacatggcg cgctttatca gaagccagac
     5941 attaacgctg ctggagaagc tcaacgaact ggacgcggat gaacaggcag acatctgtga
     6001 atcgcttcac gaccacgccg atgagcttta ccgcagctgc ctcgcacgct tcggggatga
     6061 cggtgaaaac ctctgacaca tgcagctccc ggagacggtc acagcttgtc tgtgagcgga
     6121 tgccgggagc tgacaagccc gtcagggcgc gtcagcaggt tttagcgggt gtcggggcgc
     6181 agccctgacc cagtcacgta gcgatagcgg agtgtatact ggcttaacta tgcggcatca
     6241 gtgcggattg tatgaaaagc acgccatgcc gggtgtgaaa tgccgcacag atgcgtaagg
     6301 agaaaatgca gcttccgacg ctcttccgct tcctcgctca ctgactcgct gcgctcggtc
     6361 gttcggctgc ggcaagcggt gccggctcac tcaaaggcgg aaatacggtt atccacagaa
     6421 tcaggggata aggccggaaa gaacatgtga gtaaaaaggc aaagggcaac aaaaggccgc
     6481 gccgctggcg tttttccata ggctccgccc ccctgacgag catcacaaaa atcgacgctc
     6541 aagtcagagg tggcgaaacc cgacaggact ataaagatac caggcgtttc cccctggaag
     6601 ctccctcgtg cgctctcctg ttccgaccct gccgcttacc ggatacctgt ccgcctttct
     6661 cccttcggga agcgtggcgc tttctcatag ctcacgctgt tggtatctcg gcccggtgta
     6721 ggtcgttcgc tccaagctgg gctgtgtgca cgaacccccc gttcagcccg accgctgcgc
     6781 cttatccggt aactatcgtc ttgagtccaa cccggtaaga cacgccttaa cgccactggc
     6841 agcagccact ggtaaccgga ttagcagagc gagatttatc cagatgctta cagagttctt
     6901 gaagtgatgg cccaactgcg gctacactga aaggacagta tttggtatct gcgctctgct
     6961 gaagccagtt acctcggtta agcagtcccc aactgactta accttcgact aaaccgcctc
     7021 cccaggcggt tttttcgttt acaggcagca gattacgcgc agaaaaaaag gatctcaaga
     7081 ggatcctttg atcttttact taatttcaac tcctgttagt ctggatgatg atgatggagc
     7141 aacagtccct cctttcacat cacggatgtg attgacctga catgcactaa gtgtcatgat
     7201 aaaaaacaag atcaatagaa ttttcccaca cataatttcc aaccatccaa agaaagcaac
     7261 atggatataa aagacagaaa taagatatc
//
LOCUS       DAPHKZ010000182         7279 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.183, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000182 DAPHKZ010000000
VERSION     DAPHKZ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7279
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.183"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            260..862
                     /locus_tag="RH288_004272"
     CDS             260..862
                     /locus_tag="RH288_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HDV4033256.1"
                     /translation="MKNDKAWIGDLLGGPLMSRESRVIAELLLTDPDEQTWQEQIVGH
                     NILQASSPNTAKRYAATIRLRLNTLDKSAWTLITEGSERERQQLLFVALMLHSPVVKD
                     FLAEVVNDLRRQFKEKLPGNSWNEFVNSQVRQHPVLASYSDSSIAKMGNNLVKALAEA
                     GYVDTPRRRNLQAVYLLPETQAVLQRLGQQDLISILEGKR"
     gene            859..1461
                     /locus_tag="RH288_004273"
     CDS             859..1461
                     /locus_tag="RH288_004273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HDV4033257.1"
                     /translation="MIDPVLEYRLSQIQSRINEDRFLKNNGSGNEIGFWIFDYPAQCE
                     LQVREHLKYLLRHLEKDHKFACLNVFQIIIDMLNERGLFERVCQQEVKVGTETLKKQL
                     AGPLNQKKIADFIAKKVDLASLDFVILTGMGNAWPLVRGHELMSALQDVMGFTPLLMF
                     YPGTYSGYNLSPLTDTGSQNYYRAFRLVPDTGPAATLNPQ"
     gene            1473..5114
                     /gene="brxC"
                     /locus_tag="RH288_004274"
     CDS             1473..5114
                     /gene="brxC"
                     /locus_tag="RH288_004274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HDV4033258.1"
                     /translation="MNIEQIFEKPLKRNINGVVKAEQTDDASAYIELDEYVITRELEN
                     HLRHFFESYVPATGPERIRMENKIGVWVSGFFGSGKSHFIKILSYLLSNRKVTHNGTE
                     RNAYSFFEDKIKDALFLADINKAVHYPTEVILFNIDSRANVDDKEDAILKVFLKVFNE
                     RIGYCADFPHIAHLERELDKRGQYETFKAAFADINGSRWEDERDAYYFISDDMAQALS
                     QATQQSLEASRQWVEQLDKNFPLDINNFCQWVKEWLDDNGKNILFMVDEVGQFIGKNT
                     QMMLKLQTITENLGVICGGRAWVIVTSQADINAAIGGMSSRDGQDFSKIQGRFSTRLQ
                     LSSSNTSEVIQKRLLVKTDEAKAALAKVWQEKGDILRNQLAFDPTTTTALRPFTSEEE
                     FVDNYPFVPWHYQILQKVFESIRTKGAAGKQLAMGERSQLEAFQTAAQQISAQGLDSL
                     VPFWRFYAAIESFLEPAVSRTITQACQNGILDEFDGNLLKTLFLIRYVETLKSTLDNL
                     VTLSIDRIDADKVELRRRVEKSLNTLERLMLIARVEDKYVFLTNEEKEIENEIRNVDV
                     DFSAINKKLASIIFDDILKSRKYRYPANKQDFDISRFLNGHPLDGAVLNDLVVKILTP
                     KDPTYSFYNSDATCRPYTSEGDGCILIRLPEEGRTWSDIDLVVQTEKFLKDNAGQRPE
                     QATLLSEKARENSNREKLLRVQLESLLAEADVWAIGERLPKKSSTPSNIVDEACRYVI
                     ENTFGKLKMLRPFNGDISREIHALLTVENDTELDLGNLEESNPDAMREVETWISMNIE
                     YNKPVYLRDILNHFARRPYGWPEDEVKLLVARLACKGKFSFSQQNNNVERKQAWELFN
                     NSRRHSELRLHKVRRHDEAQVRKAAQTMADIAQQPFNEREEPALVEHIRQVFEEWKQE
                     LNVFRAKAEGGNNPGKNEIESGLRLLNAILNEKEDFALIEKVSSLKDELLDFSEDRED
                     LVDFYRKQFATWQKLGAALNGSFKSNRSALEKDAAAVKALGELESIWQMQEPYKHLNR
                     ITPLVEQVQNVNHQLVEQHRQHALERIDARIEESRQRLLEAHATSELQNSVLLPMQKA
                     RKRAEVSQSIPEILAEQQETKALQMDADKKINLWIDELRKKQEAQLRAANEAKRAAES
                     EQTYVVVEKPVIQPVPKKTHLVNVASEMRNATGGEVLETTEQVEKALDTLRTTLLAAI
                     KAGDRIRLQ"
     gene            5160..>7279
                     /gene="pglX"
                     /locus_tag="RH288_004275"
     CDS             5160..>7279
                     /gene="pglX"
                     /locus_tag="RH288_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HDV4033259.1"
                     /translation="MNTNNIKKYAPQARNDFRDAVIQKLTTLGITSDKKGNLQIAEAE
                     AIGETVRYGQFDYPLSTLPRRERLVKRAREQGFEVLVEHCAYTWFNRLCAIRYMELHG
                     YLDHGFRMLSHPETPAAFEVLDHVPEVAEALLPENKAQLVEMKLSGNQDEVLYRELLL
                     GQCHALHHAMPFLFEAVDDEAELLLPDNLTRTDSILRGLVDDIPEEDWEQVEVIGWLY
                     QFYISEKKDAVIGKVVKSEDIPAATQLFTPNWIVQYLVQNSVGRQWLQTYPDSPLKDK
                     MEYYIEPAEQTPEVQAQLAAITPASIEPESIKVLDPACGSGHILIEAYNVLKNIYEER
                     GYRGRDIPQLILENNIFGLDIDDRAAQLSGFALLMMARQDDRRIFTRDVRLNIVSLQE
                     SLHLDIAKLWQQLNFHQQVQTGSMGDMFAENTALTQTDSAEYQLLMRTLKRFVNAKTL
                     GSLIQVPQEEEAELKVFLDALYRLEQEGDFQQKAAAKAFIPFIQQAWILAQRYDAVVA
                     NPPYMGGKGMNGELKEFAKNNFPDSKADLFAMFMQHAFSLLKENGFNAQVNMQSWMFL
                     SSYEALRGWLLNNKTFITMAHLGARAFGQISGEVVQTTVWVVNNNHTEFYRPVFFRLI
                     NGSEEEKKSALISRKNMFNHTLQNDFKKIPGYPIAYWLPNLSIFNNMKASDLCKSGGR
                     CKTHNDSKYVRYFWEVDMNSSKWRP"
BASE COUNT         2017 a         1694 c         1820 g         1748 t
ORIGIN      
        1 taatacagtt aaaattttat ttcttgagct gtaatcgatt aagttgatgc atttaatggg
       61 aatgatatag ggtcatttcc agtctcactt atagaaatgg ctaaagcatg actctcgcca
      121 aaaccgttta tgtgttgtac ataacgcgat catccctctc acaaattgcc ttttctcatg
      181 gcatctcgcc cggtccccca ttacaatcac tttttgtttt ttgcgagctg cattccagtc
      241 ttcagagggt ttttcgatga ttaaaaatga caaggcatgg ataggagact tgctgggcgg
      301 accgctcatg agcagggaaa gccgcgtcat tgccgaactg ttgctaaccg atcccgatga
      361 acagacatgg caagagcaaa ttgttggcca caacatttta caagcctctt ctcctaacac
      421 cgcaaaacgt tacgcggcaa caatcaggct tcgcctgaac acgctggata aaagcgcgtg
      481 gacattgatt accgaaggta gtgaacggga acgccaacaa cttctgtttg tggctctgat
      541 gctacattcg ccggtagtta aggattttct ggctgaagtg gtgaacgatc tgcgcaggca
      601 gttcaaggaa aagttgcctg gcaatagctg gaacgaattt gtgaatagcc aggttcgcca
      661 acatccggta ctcgccagct actcagattc atctattgca aaaatgggaa acaatctggt
      721 gaaggcgctt gctgaagcgg gttatgtgga tacgccccgc agacgtaacc tgcaggcagt
      781 ttacctttta ccggaaactc aggcagtgtt acagcgcctg gggcaacagg acttgatatc
      841 tattctggag ggaaaacggt gatagatccc gttcttgaat atcgcctgtc tcaaatccag
      901 agtcgcatta acgaagatcg cttcctcaaa aataacggct ccggaaatga aattggtttt
      961 tggatctttg attatcccgc gcagtgcgaa ctgcaggtac gggagcattt gaaatatctg
     1021 ctccggcatc tggaaaagga ccataaattt gcctgtctga atgtcttcca aatcatcatc
     1081 gatatgctca atgaacgcgg ccttttcgag cgcgtctgcc agcaggaagt caaagtgggt
     1141 actgagacgc tgaaaaagca gcttgctggt ccgttaaatc agaaaaagat cgctgatttt
     1201 atagcgaaaa aagtcgatct ggcttccctg gattttgtca ttcttaccgg tatgggcaac
     1261 gcctggccat tagtacgcgg tcatgaactg atgagtgcct tgcaggatgt catggggttc
     1321 accccactgc tgatgtttta tcctggcacc tacagcgggt ataacctttc cccgctcaca
     1381 gacaccggct cacaaaatta ttatcgcgct ttcagactgg taccagatac gggacccgca
     1441 gcaacattga atcctcaatg aagagcatag caatgaatat tgaacagatt tttgaaaaac
     1501 ctctaaaacg aaatataaac ggggtagtca aagcagagca aaccgatgat gccagcgcgt
     1561 acatcgagtt agatgaatat gtcatcaccc gcgaactgga aaaccatctt cgccatttct
     1621 tcgaatccta tgttcctgcc actggcccgg aaaggatccg tatggaaaac aagatcggcg
     1681 tatgggtttc aggcttcttc ggttcaggta aatcgcactt tattaagatt ctttcttatc
     1741 ttttatctaa ccgcaaagtt acacataacg gaacggaacg taatgcttac tccttctttg
     1801 aagataaaat caaagatgca ttattccttg ccgatattaa caaagcggtg cattacccga
     1861 ctgaagtcat tctgttcaat attgattcgc gtgccaacgt agatgacaaa gaagatgcca
     1921 ttcttaaagt cttcctgaaa gttttcaacg aacgcattgg ctactgcgct gattttccgc
     1981 atattgccca tcttgagcgc gaactggata aacgcggtca gtatgaaacc tttaaagccg
     2041 cgtttgccga tatcaatggc tcacgctggg aagacgagcg cgacgcttac tacttcatca
     2101 gcgatgacat ggcacaagca ttaagccagg ctacgcagca gagtcttgaa gcctcccgtc
     2161 aatgggtgga acaactcgac aaaaacttcc cgctggatat caataatttt tgccagtggg
     2221 taaaagagtg gctggatgat aatggtaaga acatcctctt tatggtggat gaagtcggtc
     2281 agttcattgg caaaaatacg caaatgatgc tgaagctgca gactattact gaaaaccttg
     2341 gggtaatctg cggtggtcgc gcatgggtta tcgtgacttc gcaggccgat atcaacgcgg
     2401 caatcggtgg tatgagcagt cgcgacggac aggacttctc caagatccag gggcgctttt
     2461 ctacacgcct gcaactttcc agctctaaca catcagaagt tatccagaaa cgtttgttgg
     2521 tcaagactga cgaagcaaaa gcggcgctgg caaaagtgtg gcaagagaaa ggcgatatcc
     2581 tgcgtaacca gctggctttt gaccctacaa caactactgc actacgtcct tttaccagcg
     2641 aagaagagtt cgttgacaac tacccgtttg tcccgtggca ctatcagatt ctgcaaaaag
     2701 tgtttgaatc tattcggacg aaaggtgcag cgggtaaaca gttggccatg ggtgagcgtt
     2761 ctcagctgga ggcattccag actgcggcgc agcaaatctc agcgcaaggg ctggattctc
     2821 tggtgccttt ctggcgcttc tatgccgcca ttgagagctt cctggaacct gccgttagcc
     2881 gcaccatcac tcaggcttgc cagaatggca ttcttgatga gttcgatggc aacctgctta
     2941 aaacgctgtt cctgatccgc tatgtggaaa cgctgaaaag caccctggat aacctggtca
     3001 cattgtctat cgataggatc gatgccgata aagttgagtt gcgccgccgg gtcgaaaaaa
     3061 gtctgaacac gcttgaacgc ctgatgctca ttgcgcgcgt tgaagataaa tatgtgttcc
     3121 tgaccaacga agagaaagag atcgaaaacg agatccgtaa cgttgatgtc gatttctctg
     3181 cgatcaacaa aaaactggca tcgatcatct ttgatgacat tctgaaaagc cgtaaatatc
     3241 gttatccggc taacaagcaa gactttgata tcagtcgctt cctgaacggg cacccattag
     3301 acggcgcagt gcttaacgat ctggtggtga agatcctgac ccctaaagat ccgacttatt
     3361 cgttctataa cagcgatgcg acctgtcgcc cttatacgtc agaaggcgac ggctgtattt
     3421 tgattcgtct gcccgaagag ggccgtacct ggagcgatat tgatttagtc gtccagactg
     3481 aaaagttcct caaagataac gccgggcaac gtccggaaca ggctaccctg ctctcagaaa
     3541 aagcgcgtga aaacagcaac cgggaaaaat tactccgtgt tcagttggaa tcactacttg
     3601 cagaagcaga tgtctgggcg attggcgagc gcttaccgaa aaaatcctcc acgccatcga
     3661 acattgtcga tgaagcctgc cgttacgtga ttgaaaacac cttcggcaag ctgaagatgc
     3721 tgcggccttt taacggtgac atctcccgtg aaattcatgc attactgacg gttgagaacg
     3781 acaccgaact ggatctcggt aacctcgaag agtccaaccc cgacgccatg cgcgaggtag
     3841 aaacctggat cagcatgaat atcgaataca ataaaccggt gtatttacgc gatattctga
     3901 accatttcgc gcgtcgccct tatggctggc ccgaagacga agtgaaactg ctggtagccc
     3961 gtctggcctg caagggtaag tttagcttca gccagcaaaa caacaacgtc gagcgaaaac
     4021 aggcgtggga gttatttaat aacagccgcc gccatagcga attgcgtctg cataaagttc
     4081 gccgtcatga tgaagcgcag gtgcgtaaag ccgcgcaaac catggctgac atcgctcagc
     4141 agccgtttaa cgaacgggaa gagccggcgc tggttgaaca tattcgtcag gtatttgaag
     4201 agtggaagca agagctgaac gtattccgcg ccaaggcaga gggcggaaac aatccgggga
     4261 aaaacgagat tgaatccggt ctgcgcctgc ttaatgccat tcttaatgag aaagaagatt
     4321 ttgccctgat cgaaaaagta tcatcgctga aagatgaact tctggatttc agcgaagatc
     4381 gtgaagattt ggtcgatttc taccgtaagc aattcgccac ctggcaaaaa ctgggggctg
     4441 cgctgaatgg cagctttaaa tctaaccgca gcgcgctgga aaaagacgcc gcggcggtta
     4501 aagcgctggg cgagctggaa agcatctggc aaatgcagga accttataag catctaaatc
     4561 gtatcacgcc gttggttgaa caggtccaga acgtcaacca tcagttagtc gaacagcacc
     4621 gccagcacgc cctcgaacgc attgacgccc gcattgagga aagtcgtcaa cgcttgctgg
     4681 aagcgcacgc cacgtcagag ctgcaaaaca gcgttctgct gccgatgcaa aaagccagaa
     4741 aacgcgctga agtcagccag tcgattccgg aaattttggc ggaacagcaa gagacaaaag
     4801 cgctgcaaat ggatgcagat aaaaagatta acctgtggat cgacgagctg cgtaaaaagc
     4861 aagaagcaca actccgggca gcaaatgaag ccaaacgcgc tgccgagtca gaacagactt
     4921 atgttgtggt agaaaaaccc gttatccaac cggtgccgaa aaaaacgcat ctggtgaatg
     4981 ttgccagtga gatgcgtaat gccaccggtg gtgaggttct ggaaacgacc gaacaggtgg
     5041 aaaaggcgct cgacacgtta cgcacaacgc tgctggccgc cattaaagca ggcgatcgca
     5101 ttcgccttca gtaactccca tttcagggca gcactctgct gccctttgca ggattttcta
     5161 tgaataccaa taacatcaaa aaatatgccc cacaggcccg taacgatttc cgcgatgcgg
     5221 tgatccagaa gctaacgacg cttgggatca cttcagataa aaaaggcaat ttgcagattg
     5281 ccgaggccga agccattggc gagaccgtgc gttacggtca gtttgattac ccgttatcga
     5341 cccttccccg ccgcgaacgg ctggtaaaac gcgcccgtga gcagggtttt gaggtgctgg
     5401 ttgagcactg cgcctacacc tggtttaacc gcttatgtgc aattcgctat atggagctgc
     5461 acggttatct tgatcacggc ttccgtatgt tatcccaccc ggaaaccccg gccgcgtttg
     5521 aggtgctgga tcatgtaccg gaagtggcag aagctctgct gccggaaaat aaagcgcagc
     5581 tggttgaaat gaagctttcc ggtaatcagg atgaagttct gtaccgtgaa ctgctgctgg
     5641 ggcagtgcca cgccctgcac cacgcgatgc cgttcctgtt tgaagcggta gatgacgaag
     5701 cggaactgct gctgccggat aacctgaccc gtaccgactc cattctgcgt gggttggttg
     5761 atgatattcc ggaagaagac tgggagcagg tagaggttat cggctggctg tatcagttct
     5821 atatttcgga aaagaaagat gccgtgattg gcaaagtggt gaagagcgaa gatattcctg
     5881 ccgccaccca gctgtttacg ccaaactgga ttgtgcagta tctggtacag aactccgttg
     5941 gccgccagtg gttgcagacc tacccggact cgccgctgaa agacaaaatg gagtactaca
     6001 ttgagcctgc ggagcaaacg ccggaagtgc aggcgcagct ggcggcgatt accccagcca
     6061 gcattgaacc cgaaagtatt aaagtgctcg acccggcctg cggttccggt catattttga
     6121 ttgaagccta taatgtgctg aaaaatatct acgaagagcg tggttatcgc gggcgtgata
     6181 ttccacaact gattctggaa aataatattt ttggtcttga tatcgacgat cgagcggcac
     6241 agctttccgg ctttgcatta ttaatgatgg cgcgtcagga tgaccgcaga atatttaccc
     6301 gcgatgtacg tctgaatatt gtctctttgc aggaaagcct gcatctggat atcgccaaac
     6361 tctggcagca gctcaatttc caccagcagg tgcaaaccgg cagtatgggg gatatgtttg
     6421 ctgaaaatac cgcgttaacc caaactgaca gcgcagaata tcagctgctg atgcgcacgt
     6481 tgaaacgctt tgtgaatgca aaaacgctgg gctcactgat tcaggtacct caggaagaag
     6541 aagcggaact gaaggtattt ctggacgcgc tgtatcgcct ggaacaggaa ggcgacttcc
     6601 aacagaaagc ggcagcgaag gcgtttattc cgtttattca gcaagcgtgg attctggcgc
     6661 agcgatatga tgcggtggtg gcaaatccgc cgtatatggg cggcaaaggg atgaatggcg
     6721 agctgaaaga gtttgccaaa aataatttcc cggatagtaa agctgatttg tttgcaatgt
     6781 ttatgcagca tgcattttct ttacttaaag aaaatgggtt taatgcacaa gtcaatatgc
     6841 aatcatggat gttcttgtcg agctacgaag cgcttcgcgg ttggttatta aataataaaa
     6901 catttatcac aatggctcat ttaggagctc gagcttttgg gcaaatttca ggtgaggttg
     6961 tacagacaac tgtatgggta gttaataata accatactga gttttaccgc cccgtatttt
     7021 tccgcttaat caatgggagt gaagaggaaa aaaaaagtgc actaatttcg cgcaaaaata
     7081 tgtttaatca caccttacaa aacgacttca aaaaaatacc cggttatcct atagcttatt
     7141 ggcttccaaa tttaagtatt ttcaataata tgaaagcatc cgatttatgt aaatcaggag
     7201 ggagatgtaa aacccataat gacagtaagt atgtaagata tttttgggag gtcgatatga
     7261 atagtagtaa atggcgacc
//
LOCUS       DAPHKZ010000183         7265 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.184, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000183 DAPHKZ010000000
VERSION     DAPHKZ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7265
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.184"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..115
                     /locus_tag="RH288_004276"
     ncRNA           <1..115
                     /ncRNA_class="other"
                     /locus_tag="RH288_004276"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(299..976)
                     /gene="narI"
                     /locus_tag="RH288_004277"
     CDS             complement(299..976)
                     /gene="narI"
                     /locus_tag="RH288_004277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDV4033260.1"
                     /translation="MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCL
                     IGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QLVRARH"
     gene            complement(976..1686)
                     /gene="narJ"
                     /locus_tag="RH288_004278"
     CDS             complement(976..1686)
                     /gene="narJ"
                     /locus_tag="RH288_004278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDV4033261.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQEMFEAIAASKNLSKEDAHALG
                     IFLRDLTAMDPLDAQAQYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLLAQYEQHG
                     LQLNSRELPDHLPLYLEYLSQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVMFDL
                     LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            complement(1683..3221)
                     /gene="narH"
                     /locus_tag="RH288_004279"
     CDS             complement(1683..3221)
                     /gene="narH"
                     /locus_tag="RH288_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDV4033262.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNV
                     ETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYE
                     PFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
                     FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCR
                     GWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYD
                     ADAIERAASTENEKDLYQRQLEVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMA
                     MEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLAN
                     LLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIA
                     NYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT
                     EPHP"
     gene            complement(3218..6961)
                     /locus_tag="RH288_004280"
     CDS             complement(3218..6961)
                     /locus_tag="RH288_004280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HDV4033263.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELEN
                     VLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWA
                     EQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVD
                     YTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQ
                     GKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVIGQKSNGNQEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLGIADNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
                     LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK"
BASE COUNT         1625 a         2046 c         1886 g         1708 t
ORIGIN      
        1 aaggatgaga agcttcgacc aaggttcgac ttgagcgcca gcgagagagc gttgccgcag
       61 gcaacgaccc gaagggcgaa gcgcgcagcg ctgagtaatc cttcccccac caccatcgct
      121 tccttaaata atcaaaacct gttactccga gctaattttg cccgatggca ccacgtttac
      181 cgggcctaca atatcctccc ctgtaggtcg gataagcgaa gcgcatccga caactcaccc
      241 cgcaccgtgc ccataaaaaa accccgccga agcagggtct atgtgaacta aaattcgctt
      301 agtgacgagc gcgcaccagc tggtacttac gtgtcagata ctccaccggt acgctccaga
      361 tgtgtaccag acgcgagaac gggaacagca ggaataacgt catccccagc accaggtgca
      421 gacggaagat aaacgccaca ccatcgaggt gttgagaagc gccaccgtgg aaggtcacca
      481 ccgactgcgc ccagccaacc agtttcatca tctcgctacc gtccatatgc tgagcggaga
      541 acggaatggt caacaggccc agcgcgcact ggataacgag cagcgacagg atcaggatat
      601 ccgctccggt agtggttgca cgcacgcgtg ggctgaacag acgacgcttc agcaacagca
      661 cgccgccaat cagacacagc acgccgctgg caccaccagc aaacatcgcc attttctgtt
      721 tcacttcaat cggcagccag gcttcataca tccagtgcgg cgtcagcata ccgaagaagt
      781 gaccaacaaa aatccccaga ataccgatat ggaacaggtt cgacgccagg ttcatccctt
      841 tgcgatccag catctggctg gacgccgcgc gccaggtgta ctgcccgtag tcataacgca
      901 gccagctacc aatcaggaag accgccccgg ctatgtacgg gtagatatca aagaagaaca
      961 tattcaggaa ttgcattagt gctgtcctcc ggtggtgata ttcagatatt gcggcgcgac
     1021 ggcaccggca aagcgacgct gatgagcagt gattgctgaa tcaccgcagc ctttgtcagc
     1081 aaagaattta acctgctctt cttcccagac agcatccagc gcctgcggcg tatcatcgcg
     1141 cgcttcgtcg gcaatttttt ccgccacttt gtcgctgtcg atagcggtat tggccaattt
     1201 cagcagcaga tcaaacatca cggcataacg gctttcacgc tgttgcagac gcgcgctcag
     1261 caatgccaga atcggcgcga tatctttcaa accttccacg gcttcgcttt gcggcagctg
     1321 cgacaggtac tccagataca gcggcagatg gtccggtaat tcgcggctgt ttaactgcaa
     1381 gccgtgctgc tcgtactgcg ccagcaggtc caccatcgcc tggccgcggt cacgggattc
     1441 accgtgaaca tgttcaaata gcaacagtga cgtggcgcgg ccacggtcga acagttcgct
     1501 gtactgggcc tgggcatcga gcggatccat cgccgttaaa tcgcgcagga aaatgcccag
     1561 cgcatgggca tcttctttcg acagattttt cgacgcagca atcgcctcaa acatctcttg
     1621 ttgatgctgc cataaggcag catccggata ttcaaggaga cgcgatacaa tcacgagttc
     1681 gatcatggat gcggctccgt tttgctggtc acatcgatgg catcgatacg acggctgttg
     1741 aacagattga atttggtatc tgaaccgtgg cagccatcac caaaggtaaa gccgcagcca
     1801 tttttctccg ggaaggcttc ccgtgccagt tcacgatgac tactcggcac cacaaagcga
     1861 tcttcgtagt tagcaatcgc cagataacgg tacatctcct gtgcctgggc ttcggtcaga
     1921 ccgacctctt ccagcgcacg ggtatcaact ttaccgtcaa cggtttcagc acgtttgtaa
     1981 tgacgcatcg ccagcatacg tttcagtgcg cgcagtaccg gtttggtatc accggcggtc
     2041 agcagattcg ccagatactg taccggaata cgcaagcttt cgacgtctgg cagaatgccg
     2101 ttgctaccca gctcacccgc gtctgctgca gactgaatcg gagacagagg cggcacgtac
     2161 cagaccatcg gcagtgtgcg atattctgga tgcagcggca gcgccagttt ccattccatt
     2221 gccattttat aaaccggcga ctgctgtgcg gcttcaataa cgctcagcgg aataccgtct
     2281 ttaatcgcct gctcgatgac tttcggatcg ttcggatcga ggaacacctc cagctgacgc
     2341 tggtaaagat ctttctcgtt ctcggtgctg gctgcacgtt caatcgcgtc ggcatcgtac
     2401 agcagcacgc caagataacg gatacgaccg acacaggttt ctgagcacac ggtcggctga
     2461 cccgcttcaa tacgcggata gcagaagatg cacttctcag acttaccgct cttccagttg
     2521 aagtagattt ttttgtacgg gcatccggtg atgcacatac gccagccacg gcatttatcc
     2581 tggtcgatca ggacgatgcc atcttcttca cgcttgtaaa tcgcaccgct cgggcaggtc
     2641 gccacacatg ccgggttcag gcagtgttcg cacaggcgcg gcaaatacat catgaaggtg
     2701 ttttcgaact ggctatacat cgccttctgg atgttgtcga agttcttgtc tttcgccagt
     2761 ttgtcaaact caccacccag gtcatcttcc cagttcggcc ctttttcgat tttcgccatc
     2821 cgttccccgg taatcagcga acgcggacgg gcaatcggct gcgatttgct gccttccggc
     2881 gcggtatgca ggttctgata gtcaaaatcg aacggctcgt aataatcgtc gatccccggc
     2941 agatgcgggt tagcgaagat tttacccagc aacatggcac ggttacccat gcgcggctgc
     3001 agtttgccgt tgattttacg gatccagccg cctttgtatt tttcctggtt ttcccagtca
     3061 gtcgggaagc cctgacccgg cttggtttcc acgttgttga accacgcgta ttccacgcct
     3121 tcacggctgg tccagacgtt tttacaggta actgaacagg tgtggcagcc gatgcactta
     3181 tcgagattca gcaccatgcc gacttgtgaa cgaattttca ttttacgctc tcctgtacct
     3241 ggtcattgcc ttcgccatct aaccagtcaa tgttcttcat cttacgcact acaacaaact
     3301 catcgcggtt agaacctacg gtgccgtagt agttaaagcc gtatgccaga tgggcatagc
     3361 cgccgatcat atgcgtcggt ttcggcgtga tacgggtgac cgagttatgg ataccaccac
     3421 gctgttgggt aatttccgaa ccaggcaggt taacgatacg ttcctgcgcg tggtacatca
     3481 tggtcatccc tgccggaaca cgctggctga caaccgcacg ggcagtcaga gcaccgttgc
     3541 tgttgaatac ttcaatccag tcgttatcgg cgatacccag atctttggca tcggcttcac
     3601 tcaaccagac caccggacca ccgcgaccta aagtcagcat cagcaggttg tcgctgtagg
     3661 tggagtggat accccacttc tggtgcggcg tcaggaagtt gagcgctttt tcctggttgc
     3721 cgttggattt ctggcctatc acttctttca ccgaacgggt gtcgatcggc ggacgataaa
     3781 ccagcaggct ttcaccgaaa tcacgcatcc actggtgatc ctgatacagt tgctgacgac
     3841 cagagagcgt acgccatggg atcagctcgt gaacgttggt gtaaccggcg ttgtaagaaa
     3901 cgtgttcatc ttccagacca gaccaggtcg ggctggagat aattttgcgc ggctgtgcct
     3961 gaatatcgcg gaagcggatc ttctcgtctt ctttattcag cgccagatgc gtatggtcac
     4021 gaccggtaaa ttcgctcagg gcagcccagg ctttcacggc tacctgaccg ttggtttccg
     4081 gtgccagtgt caggatcatc tctgccgcat caattgcggt gttcagcatc ggctggcctt
     4141 tcgccggacc ttccgctttg gtgtagttga gcttacgcag cagatccatc tcgctctggg
     4201 tgttccaggc aatcccttta ccgccattac cgattttctc catcagcggg ccgatagagg
     4261 taaagcgttc gtaagtcgcc ggataatcgc gctctacgac cataatgtgt ggcgcggttt
     4321 tacctgggat caggtcgcac tcgccttttt tccagtcttt cacatccagc ggctgcgcca
     4381 gttcagcggc agagtcatgc tggataggca gcgtgacgat gtcggtttct ttacccagat
     4441 ggccgacgca cacttcggag aatttcttcg cgatggcttt gtagatttcc cagtcgcttt
     4501 tcgcttccca ggccggatcg accgccgcag acagcgggtg aataaacgga tgcatatccg
     4561 aagtattcat gtcgtctttt tcgtaccagg tcgccgtcgg caaaatgatg tcggaataga
     4621 gacaggtgct cgacagacgg aagtccagcg taaccaccag atccagcttg ccttccagac
     4681 cattgtcctg ccagtccact tcttccggct tcacgccgcc ctgttgcccc agatctttac
     4741 cctggatacc gtgctccgtc cccagcaggt acttgagcat aaactcatga cctttaccgg
     4801 aagaaccgag caggttagaa cgccagatga acaggttgcg cgggtggttt ttaccgtttt
     4861 ctggttgttc tgccgcaaaa cggatggaac cctctttcag ggatttcacc gtatagtcca
     4921 ccggattcat cccggctttt tccgcttcgc cagcgatagt cagcgggtta gtgcctaact
     4981 gcggtgcaga cggcagccag cccatgcgtt ccgcacggac gttaaagtcg atcaagtgtc
     5041 cggtatagcg ggatttgtcc gccatcggtg acagcaactc ttccgccgtg acggtttcat
     5101 aacgccactg gctggagtgg ttatagaaat aagaagtgct gttcatgtga cgcgccggac
     5161 gctgccagtc aagggcaaac gccagcggct gccagccggt ttgcggacgc agtttttcct
     5221 gacctacata gtgcgcccag ccgcccccgc tctgaccgac acagccgcag aaaatcagca
     5281 tgttgatcag accacgatag ttcatatcga ggtgatacca gtggttcagc cccgcaccga
     5341 cgataatcat cgaacgaccg tgcgttttat cagcgttatc ggcaaattca cgggcgatgc
     5401 gaataatctg gctgcgagaa acgccggtaa tctgctcggc ccaggccggg gtataagctt
     5461 tcacatcgtc atagctggtt gcacagttaa cgtcgttcag gccacgttcc agaccgtagt
     5521 ttgccagcgt cagatcataa acggtggtca ccagggcggt gctgccatca gccagttgca
     5581 ggcgtttcac cggcagtttg tgcagcagca cgttttccag ttccactttg ttgaagtgtt
     5641 ccgtgccgtc gccaccaaag tacgggaagc ctacctcagc gatctcatcc tggctaccca
     5701 gcaggctcag ttgcagctcg gtttcttcgc cagttttgcc gtcgcgctgc tcaagattcc
     5761 atttgccctt ctcgccccag cggaagccaa tagaaccgtt cggcgcaacc atttcgccat
     5821 tggtattaaa ggcgacagtt ttccattccg gattgttttc ctggcccagc gcatcaacca
     5881 gatcagcagc gcgcagcata cgacctgcag cgtagtaacc gtcgcgttct tccagcatca
     5941 ccagcatcgg catgtcggtg tagcgacgca catagtcggt gaaatactgg cttgggttgt
     6001 cgaggtggaa ttcacgcagc attacgtggc ccatcgccag cgccattgcc gcatcggtgc
     6061 cctgtttcgg tgccagccac agatcgcaca gtttggcgat ttcagcgtag tctggtgtga
     6121 cggcaacagt tttggtccct ttgtaacgca cttcagtaaa gaagtgagca tccggggtac
     6181 gcgtctgcgg cacgtttgac ccccaggcga tgatgtagct ggagttgtac cagtcagcag
     6241 attccggtac gtcagtttgc tcgccccagg tttgcggaga cgcaggaggc aagtcgcagt
     6301 accagtcgta gaagcttaag caagtaccgc caatcagcga gagatagcgt gcacccgatg
     6361 cgtaagaaac catcgacatt gccggaattg gcgagaaacc agcaacacgg tccgggccgt
     6421 agtttttgat ggtgtaaacg ttagatgcgg cgatcagttc gttcacctcc tgccaggaag
     6481 aacgaacaaa tccaccgcgt ccacgcgcct gcttaaagct tttcgcttta tcggcgtctt
     6541 caatgataga agcccatgcc tcaaccggat cgctatgcag cgccttcgct tcacgccaca
     6601 ttttcatcag gcgtttgcgc atcatcgggt atttcaggcg gttggcactg taaagatacc
     6661 aggagtagct ggcaccgcgc gggcagccgc gaggttcatg gtttggcaga tccggacggg
     6721 tacgcggata gtcagtctgc tgggtttccc aggtgaccag accgtttttg acgtagattt
     6781 tccagctgca ggagccggtg cagtttaccc cgtgggtaga gcggacgatt ttgtcatgct
     6841 gccaacgctg gcgatatcca tcctcccagt cacggttggt attgagaagc tggccatgcc
     6901 catcggcaaa ggtttcaccc ttctgtttga agtagcgaaa ccggtccagg aatttactca
     6961 tcggttttct cctgtgggag cctgtcggcc ctctgataaa tcgacattgc taatgtttaa
     7021 gggcaaggta acgctctgaa acagcgtggg aattgataac gatcaagagt gatggggatg
     7081 aaaaataaag taaattccta agatacccct ttaggataat taacagccac cacataacag
     7141 actgtaaatt aagacgtttt atacctgtag ttatttaaac tattaagatt tttatgcaga
     7201 tgggtattaa ggagtattcc ccatgggtaa catattaatg gctcttaatg aaatccggcg
     7261 aaata
//
LOCUS       DAPHKZ010000184         7263 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.185, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000184 DAPHKZ010000000
VERSION     DAPHKZ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7263
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.185"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1104
                     /locus_tag="RH288_004281"
     CDS             <1..1104
                     /locus_tag="RH288_004281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhiJ/YhiL family protein"
                     /protein_id="HDV4033264.1"
                     /translation="MIKPQFADRIYFSNCLPVDPTSTRPTYFGDTDGSVGAVLFALFA
                     TGHLGIMAEGENFLSQLLNIEDEVLNVLLRENFNEQLNTNVNTIISILNRRDIILESL
                     QPYLVINKDAVTPCTFLGDQTGDRFSNICGDQFIIDLLKRIMSINENVHVLAGNHETN
                     CNGNYMQNFTRMKPLDEDTYSGIKDYPVCFYDPKYKIMANHHGITFDDQRKRYIIGPI
                     TVSIDEMTNALDPVELAAIINKKHHAIINGKKFKTSRAISCRSFNRYFSVSTDYRPKL
                     EALLACSQMLGINQVVAHNGNGGRERIGETGTVLGLNARDSKHAGRMFSMHNCQINPG
                     AGPEITTPWKSYQHEKNRNGLMPLIRRRTMLQL"
     gene            1470..2537
                     /locus_tag="RH288_004282"
     CDS             1470..2537
                     /locus_tag="RH288_004282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDV4033265.1"
                     /translation="MDKSKRHLAWWVVGLLAVAAIVAWWLLRPAGVPEGFAVSNGRIE
                     ATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDTRVLQEQRLEAIAQIKEAQSAVA
                     AAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHTRSRSLAQRGAISAQQLDDDRAAA
                     ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPR
                     DGRVQYRVAEPGEVLAAGGRVLNMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAP
                     DLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELLQQHLEYVKTGLPGV
                     AWVRVNEELPWPDDLVVRLPQ"
     gene            2534..5269
                     /gene="rbbA"
                     /locus_tag="RH288_004283"
     CDS             2534..5269
                     /gene="rbbA"
                     /locus_tag="RH288_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HDV4033266.1"
                     /translation="MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLI
                     GPDGVGKSSLLSLISGARVIEQGNVMVLGGDMRDPKHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDPLSRSQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWL
                     VAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIA
                     IEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAW
                     LFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMS
                     ERFKLNDVEDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFI
                     AYLQEAAGQSNEAEAPPVVHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALM
                     GTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDEL
                     DRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWL
                     QDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVR
                     EKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCGLSVFVFGVPHKGSFLTL
                     TLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGR
                     WIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG"
     gene            5269..6393
                     /locus_tag="RH288_004284"
     CDS             5269..6393
                     /locus_tag="RH288_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV4033267.1"
                     /translation="MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTP
                     GSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIP
                     PNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
                     LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF
                     EIMMAKIWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIF
                     MGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAI
                     LYRGAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA"
     gene            complement(6558..>7263)
                     /locus_tag="RH288_004285"
     CDS             complement(6558..>7263)
                     /locus_tag="RH288_004285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1-like element ISEc1 family transposase"
                     /protein_id="HDV4033268.1"
                     /translation="TDEKSNEITAIPELLNMLDIKGKIITTDAMGCQKDIAEKIQKQG
                     GDYLFAVKGTQGRLNKAFEEKFPLKELNNPEHDSYAISEKSHGREEIRLHIVCDVPDE
                     LIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSADLTAEKFATAIRNHWH
                     VENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMRKAA
                     MDRNYLASVLAGSGLS"
BASE COUNT         1700 a         1814 c         1943 g         1806 t
ORIGIN      
        1 atgataaaac cccagttcgc tgacagaatc tatttctcca attgtttacc cgttgatccc
       61 acaagtacca gaccaaccta ttttggtgat accgatggct cagtcggtgc agttttgttc
      121 gcgcttttcg caacgggaca tttgggaatc atggctgaag gagaaaattt ccttagccag
      181 ttgcttaata tagaagatga agttctcaac gtattgctaa gggagaactt taatgagcaa
      241 cttaacacta atgttaatac aataatcagt atcctgaaca gaagagacat tattttagaa
      301 agtcttcagc cttatttagt tattaataaa gacgctgtga cgccatgtac gtttctgggc
      361 gaccaaaccg gcgatcgatt tagcaatatc tgtggtgatc aatttatcat cgatttgtta
      421 aaacgcataa tgagtatcaa tgaaaatgtt catgtattag ctggaaatca tgaaacgaat
      481 tgcaatggta actatatgca gaacttcacg cgtatgaaac cactcgatga ggatacctac
      541 tctgggataa aagattatcc tgtatgtttc tatgacccca aatacaaaat aatggcaaat
      601 catcatggga taacttttga tgatcagcga aaacgttaca ttataggacc gataacagtc
      661 tctattgatg aaatgaccaa tgctctcgat ccggtcgaat tagcggcaat tatcaataaa
      721 aagcatcatg ctataattaa tggcaaaaag tttaaaacta gccgggctat ctcttgtcga
      781 tcctttaatc gttatttttc tgtttcgaca gattacagac ctaaacttga agcactatta
      841 gcatgttcac aaatgttagg tataaatcaa gttgttgcac ataacggaaa tggtggaaga
      901 gaacgcatag gcgaaacggg gacagtttta ggtcttaacg cccgtgacag taaacatgct
      961 ggaagaatgt tcagcatgca taattgccaa attaaccctg gtgcagggcc tgagataacc
     1021 actccctgga agtcttacca gcatgaaaaa aacagaaatg gacttatgcc tttgattaga
     1081 aggcgcacaa tgttacagct ctgaaccata gacaacatga atattaatgt tactatctgg
     1141 ttgagactgt tgataaaacg taaaaaggaa tgctctgttc ctgcaactga acaggcgtga
     1201 aacgctatcc aacaggatgg ataccgtttt gtcagccagt tttatagatc acacttatga
     1261 gtatgcgtgt ttcatttacg gccaggaatg ctgatgatga caacattact acccgttttc
     1321 actaagcctt ccccgttggc gctcaatgct ctgcgcgctg gtcgtatttg ccgtttcctt
     1381 cttatcccgg atggaagaat ccgctgaacg tcgttcggcg gcagttgtaa cacgcgtcgt
     1441 ttgcttacag ggattatggc gggtcgatta tggataagag taagcgccat ctggcgtggt
     1501 gggttgtcgg gttactggcg gtggcggcta tcgtggcgtg gtggctgttg cgcccggcag
     1561 gtgtgccgga aggctttgct gtcagtaatg ggcgcattga agcgacggaa gtggatattg
     1621 ccagcaaaat tgccgggcgt atcgacacca ttctggtgaa agaaggccag tttgttcgcg
     1681 aaggtgaagt gctggcgaag atggatactc gcgtgttgca ggaacagcga ctggaagcca
     1741 tcgcgcaaat caaagaggca caaagcgccg ttgctgccgc gcaggctttg ctggagcaac
     1801 gacaaagcga aactcgtgcc gcacagtcgc tggttaatca acgccaggca gaactggact
     1861 ccgtagcaaa acgtcatacg cgttcccgtt cactggccca acgaggggct atttctgcgc
     1921 aacagctgga tgacgatcgc gccgccgctg agagcgcccg agctgcgctg gaatcggcga
     1981 aagctcaggt atcggcttct aaagcggcta tagaagcggc acgcaccaat atcattcagg
     2041 cgcaaacccg cgtcgaagcg gcacaagcca ctgaacggcg cattgccgca gatatcgatg
     2101 acagcgaact gaaagccccg cgtgacggac gcgtgcagta tcgggttgcc gagccaggcg
     2161 aagtgctggc ggcaggcggt cgggtgctga atatggtcga tctcagcgac gtctatatga
     2221 ctttcttcct gccaaccgaa caggcgggca cgctgaaact gggcggtgaa gcccggctga
     2281 tcctcgatgc cgcgccagat ctgcgtattc ctgcaaccat cagttttgtc gccagtgtcg
     2341 cccagttcac gccaaaaacc gtcgaaacca gcgatgaacg gctgaaactg atgttccgcg
     2401 tcaaagcgcg tatcccaccg gaattactcc agcagcatct ggaatatgtc aaaaccggtt
     2461 tgccgggcgt agcgtgggtg cgggtgaatg aagaacttcc gtggcctgac gacctcgtgg
     2521 tgaggttgcc gcaatgacgc atctggaact ggttcccgtc ccgcctgtcg cgcaactggc
     2581 gggcgtgagc cagcattatg gaaaaaccgt tgcgctgaac aatatcactc tcgatattcc
     2641 ggcccgctgt atggtcgggc tgattggccc ggacggcgtc gggaagtcga gcttgttgtc
     2701 gttgatttcc ggtgcccgcg tcattgaaca gggcaatgtg atggtgctgg gcggcgatat
     2761 gcgcgacccg aagcatcgcc gcgacgtctg cccgcgcatc gcctggatgc cgcaggggct
     2821 gggcaaaaac ctctaccaca ccttgtcggt gtatgaaaac gtcgattttt tcgctcgcct
     2881 gttcggtcac gacaaagcgg agcgggaagt gcgaatcaat gagctgctga ccagcaccgg
     2941 gttagcaccg tttcgcgatc gtccggcagg gaaactctcc ggcgggatga agcaaaaact
     3001 tgggctgtgc tgcgcgttaa tccacgaccc ggaactgttg atccttgatg agccaacaac
     3061 gggggttgac ccgctctccc gctcccagtt ctgggatctg atcgacagta ttcgccagcg
     3121 gcagagcaat atgagcgtgc tggtcgccac cgcctatatg gaagaggccg aacgcttcga
     3181 ctggctggta gcgatgaatg ccggagaagt gctggcaact ggcagcgccg aagagctacg
     3241 gcagcaaacg caaagcgcta cgctggaaga agcatttata aatctgttac cgcaagcgca
     3301 acgccaggcg catcaggcgg tagtgatccc accgtatcaa cctgaaaacg cagagattgc
     3361 catcgaagcg cgcgatctga ccatgcgttt tggttccttc gttgccgttg atcacgttaa
     3421 tttccgcatt ccacgcgggg agatttttgg ttttcttggt tcgaacggct gcggtaaatc
     3481 caccaccatg aaaatgctca ccggactgct gcccgccagc gaaggtgagg cgtggctgtt
     3541 cgggcaaccg gttgatccaa aagatatcga tacccgccgt cgggtgggct atatgtcgca
     3601 ggcgttttcg ctctataacg aactcaccgt gcggcaaaac cttgagttac atgcccgttt
     3661 gtttcacatc ccggaagcgg aaattcccgc aagagtggct gaaatgagcg agcgttttaa
     3721 gctcaacgac gttgaagata ttctgccgga gtcattgccg ctcggcattc gccagcggct
     3781 ttcgctggcg gtggcggtga ttcatcgccc ggagatgtta atcctcgatg agcctacttc
     3841 tggtgtcgat ccggtggcga gggatatgtt ctggcagttg atggtcgatc tctcgcgcca
     3901 ggacaaagtg actatcttca tctccaccca ctttatgaac gaagcggaac gttgcgaccg
     3961 catctcactg atgcacgccg gaaaagtgct tgccagcggt acaccgcagg aactggttga
     4021 gaaacgcgga gccgccagtc tggaagaggc atttatcgcc tatttgcagg aagcggcagg
     4081 gcagagcaac gaagccgaag cgccgcccgt ggtacacgac accacccacg cgccgcgtca
     4141 gggatttagc ctgcgccgtc tgtttagcta cagccgccgc gaagcgctgg aactgcgacg
     4201 cgatccagta cgttcgacgc tggcgctgat gggaacggtg atcctgatgc tgataatggg
     4261 ttacggcatc agtatggatg tggaaaacct gcgctttgcg gtgctcgacc gcgaccagac
     4321 cgtcagtagc caggcgtgga cactcaacct ctccggttcc cgttacttta tcgaacagcc
     4381 gccgctcacc agttatgacg agcttgatcg tcggatgcgt gcgggcgata tcacggtggc
     4441 gattgagatc ccgcccaatt tcgggcgcga tatcgcgcgt ggtacgcctg tggaactcgg
     4501 cgtctggatc gacggagcga tgccgagccg tgctgaaacg gtaaaaggtt acgtgcaggc
     4561 catgcaccag agctggttac aggatgtggc gagccgacaa tcgacacccg ccagccaaag
     4621 cgggctgatg aatattgaga cgcgctatcg ctataacccg gacgtaaaaa gcctgccagc
     4681 gattgttccg gcggtgatcc cgcttctgct gatgatgatc ccgtcaatgc taagcgccct
     4741 tagcgtggtg cgggaaaaag agcttgggtc gattatcaac ctttacgtga cccccaccac
     4801 gcgtagtgaa tttttgcttg gtaaacagtt gccatacatc gcgctgggga tgctgaactt
     4861 tttcctgctc tgcggcctgt cggtgtttgt gtttggcgta ccgcataaag gcagtttcct
     4921 gacgctcacc ctggcggcgc tgctgtatat catcattgcc accggaatgg ggctgctgat
     4981 ctccaccttt atgaaaagcc agattgccgc cattttcgga acggcgatta tcacgttgat
     5041 cccggcgaca cagttttccg ggatgatcga tccggtagct tcgctggaag ggcctggacg
     5101 ttggatcggc gaggtttacc cgaccagtca ttttctgact atcgcccgcg ggacgttctc
     5161 gaaagcgctg gatctgactg atttgtggca actttttatc ccgttgctga tagccatccc
     5221 gctggtgatg ggcttaagta tcctgctgct gaaaaaacag gagggatgat gcgccattta
     5281 cgcaatattt ttaatctggg tatcaaagag ttgcgcagtc tgctcggtga taaagcgatg
     5341 ctgacgctga ttgtcttctc gtttacggtg tcggtgtatt cgtcagcgac cgttacgcca
     5401 ggatcgttga acctcgcgcc gatcgccatt gccgatatgg atcaatcgca gttatcgaac
     5461 cggatcgtta acagcttcta tcgtccgtgg tttttgccac cggagatgat caccgccgat
     5521 gagatggatg ccggactgga cgccggacgc tataccttcg cgataaatat tccgcctaat
     5581 tttcagcgtg atgtcctcgc cggacgccag ccggatattc aggtgaacgt cgatgccacg
     5641 cgcatgagcc aggcatttac cggcaatggg tatatccaga atattatcaa cggtgaagtg
     5701 aacagctttg tcgcgcgcta ccgtgataac agcgaaccgt tggtatcgct ggaaacccgg
     5761 atgcgcttta acccgaacct cgatcccgcg tggtttggcg gggtgatggc gatcatcaac
     5821 aacattacca tgctggcgat tgtattgacc ggatcggcgc tgatccgcga gcgtgaacac
     5881 ggcacggtgg aacacttact ggtgatgccg ataacgccgt ttgagatcat gatggcgaag
     5941 atctggtcga tggggctggt ggtgctggtg gtatcgggat tatcgctggt gctgatggtg
     6001 aaaggtgtac tgggcgtacc gattgaaggc tcgatcccgc tgtttatgct gggcgtggcg
     6061 ctcagtctgt ttgccaccac gtcaatcggc atttttatgg ggacgatagc gcgttcaatg
     6121 ccgcaactgg ggctgctggt gattctggtg ctgctgccgc tgcaaatgct ttccggtggt
     6181 tccacgccgc gcgaaagtat gccgcagatg gtgcaggaca ttatgctgac catgccgacg
     6241 acacactttg ttagcctcgc gcaggccatc ctctaccggg gtgccggatt cgaaatcgtc
     6301 tggccgcagt ttctgacgct gatggcaatt ggcggcgcat ttttcaccat tgcgctgctg
     6361 cgattcagga agacgattgg gacaatggcg taaatacaat tgcccgatgc gtaagcttat
     6421 agggactacg catcggtgca atttattgaa ttttagttgt ttttaggccg gataaggcgt
     6481 ttatgaactg acccccaaaa cctggacagt ttcagttaac cggctttttg atactcagtc
     6541 ctgtattcag ggcaagatta cgaaagcccg ctccccgcaa ggactgacgc cagatagttt
     6601 ctgtccatgg ctgcttttcg catcttacgt cttaaccctg ccttgaatac cttatcattc
     6661 gtcaaaatat taatagcaat gtgccgtatc cctgaaaata attctgctgc atttcctctt
     6721 cttattttgc agtcgtcttc attcattacc acgtccagac gccagtgcag cttattctcc
     6781 acgtgccagt gatttcggat cgctgtggcg aatttctcag cggttaaatc agcagaactg
     6841 atataatatc tgaccgtcat ttctggctct ttcttttgtt ctgctattat ggaccgaaag
     6901 gagactgcca cgcataattt cttcagccct ttccattcaa acgtgaaatc aataagttca
     6961 tcagggacat cgcaaacaat atgaagacgg atttcttctc tgccgtgact cttttcactg
     7021 attgcgtaac tgtcatgctc tggattattt aattctttca gcggaaattt ttcctcaaag
     7081 gctttattta gccgcccctg ggttcctttt accgcgaata aataatcacc tccctgtttt
     7141 tgtatcttct ctgcaatatc tttctggcaa cccatcgcat cagttgtgat gatttttcct
     7201 ttaatatcca gcatgttaag aagttctggg atagctgtaa tctcattaga tttctcatcc
     7261 gtc
//
LOCUS       DAPHKZ010000185         7243 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.186, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000185 DAPHKZ010000000
VERSION     DAPHKZ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7243
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.186"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..205)
                     /locus_tag="RH288_004286"
     CDS             complement(<1..205)
                     /locus_tag="RH288_004286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV4033269.1"
                     /translation="MSLKHSDEFKRDAVRIALTSGLTRRQVASDLSIGLSTLGKWIAS
                     ISDETKIPTQDTDLLRENERLRKE"
     gene            complement(236..859)
                     /locus_tag="RH288_004287"
     CDS             complement(236..859)
                     /locus_tag="RH288_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDV4033270.1"
                     /translation="MLIGYARVSKADGSQSLDLQHDALRAAGVERDNIYDDLASGGRD
                     DRPGLTACLKSLRDGDVLVVWKLDRLGRSLAHLVNTVKELSDRKIGLRVLTGKGAQID
                     TTTASGRMVFGIFATLAEFERDLIRERTMAGLASARARGRKGGRKFALTKAQVRLAQA
                     AMAQRDTSVSDLCKELGIERVTLYRYVGPKGELRDHGGLASVSFRSF"
     gene            985..3870
                     /locus_tag="RH288_004288"
     CDS             985..3870
                     /locus_tag="RH288_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDV4033271.1"
                     /translation="MPRRVTLTDRQKDALLRLPTSQTDLLKHYTLSDEDLGHIRLRRR
                     AHNRFGFALQLCVLRYPGRVLAPGELIPAEVIEFIGAQLGLGADDLVDYAAREETRHE
                     HLAELRGLYGFRTFSGRGASELKEWLFREAEMAVSNEDIARRFVAECRRTRTVLPATS
                     TIERLCAAALVDAERRIETRIASRLPMSIREQLLALLEETADDRVTRFVWLRQFEPGS
                     NSSSANRLLDRLEYLQRIDLPEDLLAGVPAHRVTRLRRQGERYYADGMRDLPEDRRLA
                     ILAVCVSEWQAMLADAVVETHDRIVGRLYRASERICHAKVADEAGVVRDTLKSFAEIG
                     GALVDAQDDGQPLGDVIASGSGWDGLKTLVAMATRLTATMADDPLNHVLDGYHRFRRY
                     APRMLRLLDLRAAPVALPLLEAVTALRTGLNDAAMTSFLRPSSKWHRHLRAQRAGDAR
                     LWEIAVLFHLRDAFRSGDVWLTRSRRYGDLKHALVPAQSIAEGGRLAVPLRPEEWLAD
                     RQARLDMRLRELGRAARAGTIPGGSIENGVLHIEKLEAAAPTGAEDLVLDLYKQIPPT
                     RITDLLLEVDAATGFTEAFTHLRTGAPCADRIGLMNVILAEGINLGLRKMADATNTHT
                     FWELIRIGRWHVEGEAYDRALAMVVEAQAALPMARFWGMGTSASSDGQFFVATEQGEA
                     MNLVNAKYGNTPGLKAYSHVSDQYAPFATQVIPATASEAPYILDGLLMNDAGRHIREQ
                     FTDTGGFTDHVFAACAILGYRFAPRIRDLPSKRLYAFNPSAAPAHLRALIGGKVNQAM
                     IERNWPDILRIAATIAAGTVAPSQILRKLASYPRQNELATALREVGRVERTLFMIDWI
                     LDAELQRRAQIGLNKGEAHHALKRAISFHRRGEIRDRSAEGQHYRIAGMNLLAAIIIF
                     WNTMKLGEVVANQKRDGKLLSPDLLAHVSPLGWEHINLTGEYRWPKP"
     gene            3937..4110
                     /locus_tag="RH288_004289"
     CDS             3937..4110
                     /locus_tag="RH288_004289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001406132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV4033272.1"
                     /translation="MNGQTVGREGARNLGEVRTGVEAKVNNNLSLWGNVGVQLGDKGY
                     SDTQGMLGVKYSW"
     gene            4333..4599
                     /gene="hipB"
                     /locus_tag="RH288_004290"
     CDS             4333..4599
                     /gene="hipB"
                     /locus_tag="RH288_004290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HipB"
                     /protein_id="HDV4033273.1"
                     /translation="MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISN
                     FENNPDNTTLTTFFKILQSLELSMTLCDAKNASPESTEQQNLEW"
     gene            4599..5921
                     /gene="hipA"
                     /locus_tag="RH288_004291"
     CDS             4599..5921
                     /gene="hipA"
                     /locus_tag="RH288_004291"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system serine/threonine
                     protein kinase toxin HipA"
                     /protein_id="HDV4033274.1"
                     /translation="MPKLVTWMNNQRVGELTKLANGAHTFKYAPEWLASRYARPLSLS
                     LPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVT
                     LIPEDETVTHPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTAL
                     LRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVP
                     DAEIIKAGNVRALAVERFDRRWNAERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIA
                     RIMAFLMGSSEALKDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDII
                     SAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKIYPRHFLATAKVLRFPEVQMHEIL
                     SDFARMIPAALDNVKTSLPTDFPENVVTAVESNVLRLHGRLSREYGSK"
     gene            6233..6441
                     /locus_tag="RH288_004292"
                     /pseudo
     CDS             6233..6441
                     /locus_tag="RH288_004292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226947.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6696..7243
                     /locus_tag="RH288_004293"
                     /pseudo
     CDS             6696..7243
                     /locus_tag="RH288_004293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
BASE COUNT         1739 a         1905 c         1949 g         1650 t
ORIGIN      
        1 tctctttgcg taaacgttca ttctcacgca gaagatcagt gtcttgggta ggaattttag
       61 tttcatcgga aattgatgcg atccatttcc caagcgtgga aagcccaata cttaaatctg
      121 acgcaacttg acggcgtgtt aagccactag tgagtgctat gcgaactgca tcacgcttaa
      181 attcatcact atgctttaat gacatatatg gtctccttga taacaaataa tgctctcaaa
      241 aagaccggaa cgaaaccgag gcaagaccac catggtctct gagctcgcct ttgggaccga
      301 catatcggta gagagtgacg cgctcgatgc cgagttcctt gcagagatcg gaaactgaag
      361 tatcgcgctg ggccatggcg gcttgcgcga gacgcacctg agctttggtg agcgcgaatt
      421 ttcgtccgcc cttgcgaccg cgcgctctcg cggaggcgag acccgccatg gtgcgctctc
      481 ggatcagatc ccgctcgaac tcggccaagg tggcgaagat tccgaacacc atgcgaccgg
      541 acgcagtcgt ggtgtcgatc tgagcgccct ttccagtcag aacccgcagg ccgatcttgc
      601 ggtctgacag ctccttcacc gtgttgacca gatgggcaag cgatcgtccg aggcgatcga
      661 gcttccagac caccagcaca tcgccgtcac gcaatgactt gaggcaggca gtcaagccag
      721 ggcgatcatc acgaccgccg gaagcaagat catcatagat attgtcccgt tcgacacctg
      781 cggcgcgcaa ggcgtcgtgc tgcaggtcga gagactgcga gccatcggct ttggagacgc
      841 gggcatatcc gatcagcatg tatcacaaac gttggtttga ggcggcgctt cggccacgat
      901 tgcattgacc tctggaaatg tatctcaacc agcttcataa acaaagcgtc ttgaacgcta
      961 tcagattttg aaaaaggaac atgtatgccg cgtcgcgtca ctctaaccga tcggcagaaa
     1021 gacgcgctgt tgcgcttgcc gacttcacag acggatttgc tcaagcacta tacgctgagt
     1081 gatgaagacc ttgggcatat caggctgcgt cggcgcgctc acaacaggtt cggcttcgcc
     1141 ctgcaattgt gtgtcctgcg ctatcccggc cgggtgctgg ctccaggcga actgatccct
     1201 gcagaggtca tcgaatttat cggagcgcag cttggcctgg gtgccgacga tctcgtagac
     1261 tatgctgccc gcgaggaaac acggcacgag catcttgccg agttacgggg gctctacggc
     1321 ttccgcacct tctccggacg tggtgcgagc gagctgaagg aatggttgtt ccgagaagcc
     1381 gagatggcgg tgtcgaacga ggatatcgcc cgtcgcttcg tagccgagtg ccgacgcacc
     1441 cgcactgtcc ttcccgcgac atccacgatc gagcggcttt gtgccgcggc tctcgtcgat
     1501 gccgagcgac gcatcgagac gaggatcgcc agtcggctgc ctatgtcgat ccgagaacag
     1561 ttgctggcat tgctcgagga gacggctgat gatcgggtga cccgttttgt gtggctgcgc
     1621 cagttcgagc ctggctcgaa ctcttcgtcg gccaaccggc tgctcgaccg gctcgaatat
     1681 ctgcaacgca tcgatctccc cgaggatctg cttgccggcg ttcctgccca tcgggtgact
     1741 cgtctgcgca ggcagggtga acggtattat gccgacggca tgcgcgatct cccggaggac
     1801 aggcggcttg cgatcttggc tgtttgcgtc tcggaatggc aggcgatgtt ggccgacgca
     1861 gtggtcgaaa cccacgaccg gatcgtcggc cgtctctacc gtgcttcgga gcgtatttgc
     1921 catgcaaagg tcgcagacga agcgggggtg gtgcgtgaca ccctgaaatc cttcgccgag
     1981 atcgggggcg ccctggtcga tgcacaggat gatggccagc cgctgggcga tgtcatcgcg
     2041 agtgggtcag ggtgggacgg cttaaaaacc cttgttgcaa tggcaaccag gctgaccgcc
     2101 accatggccg acgatccgct caatcatgtg ctcgacggtt atcaccgctt ccgccgatac
     2161 gctccacgca tgttgcgcct gctcgatctg cgagctgcgc ccgttgcact gccgcttctg
     2221 gaagcggtga cggcccttcg taccggtttg aacgatgccg cgatgaccag cttcttgcgg
     2281 cccagctcga aatggcatcg ccaccttcgg gcccagaggg ctggcgacgc tcgcctatgg
     2341 gagatcgcgg tgctgttcca tctgcgcgat gcgttccgct ccggagatgt ctggcttact
     2401 aggtcccggc gctatggcga tctgaaacac gcactcgttc cggcacaatc catcgcggaa
     2461 ggcggtcgtc tcgctgtgcc attgcggccg gaggaatggc tggcagaccg gcaagctcgc
     2521 ctcgacatgc ggttgcgcga gcttggccgt gccgctcgcg caggcacgat cccgggcggg
     2581 tcgattgaaa acggcgttct gcatatcgag aaactcgaag ccgccgcgcc gacaggcgcc
     2641 gaagatctgg tgctcgatct ctacaagcag atcccgccca cgcgcatcac cgatctcctg
     2701 ctggaggtgg atgcggcgac cggcttcacc gaagcgttca cccatctgcg cacaggagca
     2761 ccctgcgctg accggatcgg gctaatgaac gttatcttgg cggaagggat caacctcggc
     2821 ttgcgcaaaa tggcggatgc gacaaacacc cacaccttct gggaattgat ccgcattgga
     2881 cggtggcatg tcgagggcga agcctatgac cgggcgctgg ccatggtggt cgaggcacag
     2941 gcagcgttac ccatggcccg gttctggggc atgggcacgt cggcttcgag cgacggacag
     3001 ttcttcgtcg ctacagagca aggtgaggcc atgaacctgg tcaacgcgaa atatggcaat
     3061 accccgggcc tgaaagccta tagccacgtc tccgaccaat atgcgccgtt cgcaacccag
     3121 gtgattcctg caacggcaag cgaagcgcct tacatcctcg atggcctgct gatgaacgat
     3181 gctggacgcc atatccgcga gcagttcacc gacacgggcg gcttcaccga tcacgtcttt
     3241 gccgcatgtg ccattctcgg ctaccggttc gctccgcgca tccgcgacct gccatccaaa
     3301 cggctctacg cgttcaatcc gtcggccgcc ccggcgcacc tgcgagcgtt gatcggcgga
     3361 aaggtcaacc aagccatgat cgagcgcaat tggcccgaca tcctgcgcat cgccgccacc
     3421 attgctgccg ggaccgtcgc gccaagccag attctgcgga aactcgcctc ctatccgcgg
     3481 cagaacgagc tcgcgacagc cctgcgggaa gtcggtcgcg tcgagcgcac cctgttcatg
     3541 atcgactgga ttctggatgc cgaactccaa cggcgtgccc agatcgggct caacaaaggc
     3601 gaagctcatc atgcgctgaa gcgggcaatc agcttccacc gccgcggtga aatccgcgac
     3661 cgttccgccg aaggccagca ttaccgcatc gccggcatga atctgctcgc cgccatcatc
     3721 atcttctgga acaccatgaa gctcggcgag gtcgttgcaa accagaaacg cgatggaaag
     3781 ctgctatcgc ccgatctctt ggcccatgtt tcgccgctcg gatgggaaca catcaatctc
     3841 accggagaat atcgctggcc aaagccttag cgtaggattc cgccccctcc cgcaaacgac
     3901 ccctggatca acaatagcaa agtctacgcc gtgaagatga atggtcaaac cgtaggccgt
     3961 gaaggtgcgc gtaatctcgg tgaagtacgt accggggttg aggcgaaagt aaataacaac
     4021 cttagcctgt gggggaatgt cggtgtgcaa ctaggtgata aaggctatag cgatactcag
     4081 ggcatgctgg gagtgaaata tagctggtaa accgtataag ccgcatgtcg agatggcatg
     4141 cggcttaata ttgccgactt caaacggcgc atcaacgcct tatttaaatc ctccttttta
     4201 tccgcgatcg cggatatcgc agcgtttatc ccgtagagcg gataagatgt gtttccagat
     4261 tgacttatcc tcactaaagg ataaaactta taatatcccc ttaagcggat aaacttgctg
     4321 tggacgtatg acatgatgag ctttcagaag atctatagcc caacgcaatt ggcgaatgca
     4381 atgaaactgg ttcgccagca aaatggctgg acgcagagcg agctggcgaa aaaaattggt
     4441 attaagcagg cgacgatttc caatttcgaa aacaaccctg acaataccac gctcacgaca
     4501 ttttttaaga ttttacagtc gcttgaactc tcaatgacgc tatgcgacgc gaaaaatgcc
     4561 tcgccagaat caacagaaca gcaaaatctg gagtggtaat gcctaaactt gtcacttgga
     4621 tgaacaacca gcgggtaggc gagttaacga agttagccaa cggcgcgcac acctttaagt
     4681 atgcaccgga gtggttagca agccgttatg ccagaccgtt gtcactttcg ctgccattgc
     4741 agagggggaa tatcacctct gatgccgtat ttaacttctt cgataacctg ttacccgata
     4801 gcccgattgt acgtgaccgg atcgttaaac gttatcatgc caaatccaga caaccgtttg
     4861 atttattgtc agaaataggg cgagacagcg ttggtgccgt gacgttaata cccgaagacg
     4921 aaaccgtaac gcatccgata atggcatggg aaaagcttac tgaagccaga cttgaagaag
     4981 tattaacggc ttataaagca gatatcccgc taggcatgat tagagaagaa aatgactttc
     5041 gcatctcggt tgctggcgca caggagaaga cagcactgct cagaataggc aatgactggt
     5101 gcattccgaa aggaataacg ccgacgacgc acatcattaa attaccgatt ggcgaaatca
     5161 ggcagcccaa tgcgacgctc gatctcagcc aaagcgttga taatgagtat tactgtctgc
     5221 tgctggcgaa agaacttggg ttgaatgttc cggacgcaga aatcattaaa gcgggaaatg
     5281 tgcgcgcgtt agcggtcgaa cgttttgaca ggcgttggaa tgctgagcga acggttttac
     5341 ttcgcttgcc acaggaggat atgtgtcaga cattcggttt accttcatcg gtgaaatatg
     5401 aatcagatgg aggcccaggc atcgcgcgga tcatggcttt tttgatgggg tccagcgagg
     5461 cgctgaaaga tcgctatgat tttatgaaat tccaggtctt ccagtggttg attggcgcaa
     5521 cggacggtca tgcaaaaaac ttctccgtat ttattcaggc tggcggcagt tatcgactca
     5581 cgccatttta cgacatcatt tcagcatttc cggtccttgg cggtacggga atacacatca
     5641 gcgatctcaa actggcaatg gggcttaacg catccaaagg caaaaaaacg gcaatcgata
     5701 aaatttatcc gcgacatttt ttggcgacag caaaggtgct gagattcccg gaagtgcaga
     5761 tgcatgaaat cctgagtgac tttgccagaa tgattccagc agcactggat aacgtgaaga
     5821 cttcattacc gacagatttt ccggagaacg tggtgacggc agttgaaagc aatgtgttga
     5881 ggttgcatgg acggttaagc cgagaatacg gtagtaagtg agatatgggg tttggtcatt
     5941 gttaatgagc atgacaatca tgaccgccaa cgactggatt cttccttggt ttatattggt
     6001 gcgcataatg tatattatgt taaatcatgt ctgagtgatg cgaagtgctt ttctggtagt
     6061 cgttattcgt tcagggttca agaacttaag cctctcctct ttcataattg gcctgtgcat
     6121 ggagaaatag cctggttatt ccctgcccca tgctaagagc gcagtgtctg tcgcatagac
     6181 actgcatacg aaaacaccag agggtgctgt tacttattta aggacggatc aagcgggaat
     6241 gagtccactc cggtatcaga aatggctacg tctcaatgaa gtcaggcgac agatgctgaa
     6301 tgaacattac gatgtcacca cagcagccta tgctgtcggt tacgaaagct atcccatttc
     6361 agtcgggaat attcgcggat gtttggagag tcacccaaga gagatattac caggttaaga
     6421 aagtctgtcg gacagcttta ataaaccctg cacttatctg tttagagcaa ttcggtgtta
     6481 gtttcagcaa gcaaacatta accatagcta atgatttata gccatattaa ccattggtag
     6541 ctcttgacct ttcctgacac ttcccttgtt cgcaataata ttctgtttag tcacggttta
     6601 taaataacat gcataatgaa atcgtcatgt tatttagcga cataaaatgt ttttgcaaat
     6661 actctcttca acaagtgcag caataaactt gttgtggaac caatatccag gtcgcaggat
     6721 atcgctattc tacgcaaggt ttttataact tatccgacag tgcctacagt cgaatgagtg
     6781 gttacaccgt caagcctcct accggagaca gcaacgagca gacacaattt attgattatt
     6841 ttaatctgtt ctacagtaag cgtggtcagg aacaaataag catctctcag cagcttggaa
     6901 attacggtac gacatttttc agtgccagtc gccaaagtta ctggaacacg tcacgcagcg
     6961 accagcaaat atcatttgga ttaaatgtgc cgtttggtga tattacgact tcgctgaatt
     7021 acagctattc caataatata tggcaaaacg atcgggatca tttacttgct tttacgctta
     7081 atgttccctt cagtcattgg atgcgtacag acagtcagtc ggcatttcgt aattcaaacg
     7141 ccagttacag tatgtcaaac gatttgaaag gcggcatgac caatttatcg ggggtttatg
     7201 gcactctgct gccggataat aacctgaatt atagcgttca ggt
//
LOCUS       DAPHKZ010000186         7126 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.187, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000186 DAPHKZ010000000
VERSION     DAPHKZ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7126
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.187"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(100..2883)
                     /locus_tag="RH288_004294"
     CDS             complement(100..2883)
                     /locus_tag="RH288_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310126.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDV4033275.1"
                     /translation="MRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMI
                     YPHAHPKDQVNLWLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMG
                     LRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVI
                     TEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQP
                     NNMTFIVVGDIDSKEALALIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRV
                     NGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVK
                     IAPDYQSLFFRVNARDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAV
                     DQQAERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQKITVQSLAEKWQQLRKNQ
                     DAFWEQMVNNEVAAKKALSPAAILALEKEYANKKLAAYIFPGRNLSLTVDADPQAEIS
                     SKETLADNLTSLTLSNGARVILAKSAGEEQKLQIIAVSNKGDLSFPAQQKSLIALANK
                     AVSGSGVGEHSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARANNPEPGFQLINQRIT
                     HSTINDNIWASLQNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQEKQIAQFTA
                     ADALAADRQLFSSPADITFVIVGNVAEDKLVALITRYLGSIKHSDSPLAAGKPLTRAT
                     DNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMALDAFNVALAKDLRVNIREQASG
                     AYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQ
                     QNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLS
                     HPVDTYTGVLLPK"
     gene            complement(2940..5312)
                     /locus_tag="RH288_004295"
     CDS             complement(2940..5312)
                     /locus_tag="RH288_004295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HDV4033276.1"
                     /translation="MKRVLIPGVILCGADVAQAVDDKNMYMHFFEEMTVYAPVPVPVN
                     GNTHYTSESIERLPTGNGNISDLLRTNPAVRMDSTQSTSLNQGDIRPEKISIHGASPY
                     QNAYLIDGISATNNLNPANESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFG
                     RFNGGVIDAKIKRFNADDSSVKLGYRTTRSDWLTSHIDENNKSAFNQGSSGSTYYSPD
                     FKKNFYTLSFNQELAENFGVTAGLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALS
                     KFTWYASDRFTHDLTLKYTGSSRDYNTSTFPQSDREMGNKSYGLAWDMDTQLAWAKLR
                     TTVGWDHISDYTRHDHDIWYTELSCTYGDITGRCTRGGLGHISQAVDNYTFKTRLDWQ
                     KFAVGNVSHQPYFGAEYIYSDAWTERHNQSESYVINAAGKKTNHTIYHKGKGSLGIDN
                     YTLYMADRISWRNVSLMPGVRYDYDNYLSNHNISPRFMTEWDIFADQTSMITAGYNRY
                     YGGNILDMGLRDIRNSWTESVSGNKTLTRYQDLKTPYNDELAMGLQQKIGKNVIARAN
                     YVYREAHDQISKSSRTDSATKTTITEYNNDGKTKTHSFNLSFELAEPLHISQVDINPQ
                     IVFSYIKSKGNLSLNNGYEESNTGDNQVVYNGNLVSYDSVPVADFNNPLKISLNMDFT
                     HQPSGLVWANTLAWQEARKARIILGKTNAQYISEYSDYKQYVDEKLDSSLTWDTRLSW
                     TPQFLKQQNLTISADILNVLDSKTAVDTTNTGVATYASGRTFWLDVSMKF"
     gene            complement(5350..7035)
                     /locus_tag="RH288_004296"
     CDS             complement(5350..7035)
                     /locus_tag="RH288_004296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HDV4033277.1"
                     /translation="MITIPITFCMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILG
                     VVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPALLGIFVLISVNKTWLIKLLTIR
                     WREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
                     SLSMLITFTVILWQSAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRP
                     LNVEKQRSEATFRTNLVQHNKQAELIALSNAESLQRQELSDNFHTIKENWHRLMNRQR
                     WLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFMLVSNNLSWFIYKYDE
                     LAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADASIRTPDNKIILENLNFHVSP
                     GKWLLLKGYSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKTGLLKEIICK
                     ALPLPVDDKSLSEVLHQVGLGKLAARIHDHDRWGDILSSGEKQRIALARLILRRPKWI
                     FLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAVL"
BASE COUNT         1850 a         1626 c         1587 g         2063 t
ORIGIN      
        1 agtacttggt tattattttg aacgcattta taaaattatt acataaaaat agcgaatatt
       61 gctaaaatcc ccgccaacga tgtgttgacg gggctgttat tattttggca ataatactcc
      121 agtataagta tctaccggat gagaaagata ttgtttaacg gcagtgttaa cattctctac
      181 cgtcatttgt ttcaacaatt gctcctgctc agtccatgct gcaggatcgt catattgaat
      241 aagactattt acaatagtgt tcgctaattg ttgaacgcta cgctgttgga tatcgaggct
      301 gcgctgaacg ttttgctggt attcattcag ttcttgctca ctgatccctt tagccagacg
      361 cttaaccatc acttcattcg ctaacgttaa cagttcatca tgtcgttctg gttgacaagt
      421 aaaagccagc aaatgactga tatctttggc ctgaggatca accgagaggc gagaagaaac
      481 gctgtatgct ccagatgcct gttcacgaat attaacgcgt agatcttttg ccagtgcgac
      541 gttaaaagca tcgagcgcca tacgcgtcgc cagattaaca ggtgtccggg aatcataacg
      601 cttccactgt gaaacctgtg ccacaggttc attttgttct tttacagtaa ccgatgcgtt
      661 gtccgtcgcg cgagttaatg gtttacctgc ggctaatggc gaatcagagt gtttgattga
      721 tcctaagtaa cgcgtaatta acgccacgag tttgtcttct gcgacattac cgacaatgac
      781 aaacgtgata tccgctggag atgaaaacaa ctggcgatcg gcagccagcg catctgcggc
      841 agtaaactgt gcaatctgtt tttcttgcag taatttcgtg cggtcatcag catagcgcgt
      901 ctcatacatc tgctgggcga atttctccgc tggacgctgg tcgagcgttt tcaacgcctg
      961 aatttgagca ttttgtagcg atgcccaaat attgtcgtta atcgtgctgt gggtgattcg
     1021 ctggttaatt aactggaaac caggttcagg gttattagcc cgcgcgctaa cggagagcaa
     1081 cgtattcatg ccactgactt tactgctcat ggttaccgag ttttccgcac tccagcgttt
     1141 caggctggaa gaggagtgtt caccaacgcc gcttccgctt actgctttat ttgccagcgc
     1201 gatcagtgat ttttgctgcg cagggaaact taaatcgcct ttattcgata cggcaataat
     1261 ttgtagcttt tgctcttcac ccgcggattt tgccagaata accctggcac cattagaaag
     1321 tgttaatgat gtcagattat cagccagcgt ttctttgctg ctaatttccg cctgtgggtc
     1381 agcgtctact gttaacgata aatttctgcc tgggaatatg taagccgcca gctttttgtt
     1441 ggcgtactct ttttccagcg ccaggatagc cgcaggagac aatgcttttt tggcggcaac
     1501 ctcattgttt accatttgct cccaaaatgc gtcctggttc tttcttaact gctgccattt
     1561 ttccgccaga ctttgcacgg taattttctg ccacagacgt ttcgaaagtt gatatgtctc
     1621 ttccggcgac aagaacggcg tattatttaa tgagctggat gccaggcgac tggtcagcat
     1681 acgtaaatca cgttcagctt gctgatcaac cgcatttttc agccaggtga ggcgggtaga
     1741 tttgacatca tcgagttctt cagcagaaaa accatgctga tcaatggttg ccaactccgc
     1801 cattaatgca ttcgcagcat cctgcatatt atcgtctcgt gcatttacac ggaaaaacag
     1861 cgactgataa tcgggtgcaa ttttaacgct gcgcgcagtg ccgccagaaa tagtcttcaa
     1921 ctcgcccgac tgtatgcgtt cctgcagacg ttgattgaac agctgaacta acatgctcca
     1981 ttcagcttgt tcgataaagc tttgctcatc gttcacttgt accattggca ggcgataata
     2041 gagtgcgatg ccgttcaccc ggttttcttt atcattaatg atattaaagc gcaggtgatt
     2101 ttcggctttt gtcggccaga cgcgattttc agctgctttg ttagccggaa gcttacttaa
     2161 attatccttt atcagcgcca gcgcttcttt actgtcgata tcgccgacca cgataaaggt
     2221 catattattt ggttgatacc agcgttgata aaattggcgc aattgtgccg gtgtgaccgt
     2281 ggcgacagta tccatcaggc cgataggttc acggtctaaa ttacgggtat ttgccagcag
     2341 gaaagggcgg cgcgcctgag aggtgcgcca tttcgcatcc tgatgggcac gccattcctc
     2401 agtaattacg ccgcgttcag cgtctacttc gagtttttca aaggttgcgg cattactcca
     2461 ttcactgaag attgccatca cttgttgcag attttgtttc tgcgtagtcg gcaaactcac
     2521 ctgatacacc gtttcgtcat agctggtata ggcattaaca tcgcgaccaa aacgcaggcc
     2581 cattgactca aatgtttcga tgactttatt acccggccat gtttttgtgc cgttaaacat
     2641 catatgttct acaaaatgag ccacgccgcg ctcattgtct tcttcctgca atgaaccggt
     2701 atgaatttgc agccataaat ttacctgatc ctttggatga gcatgcggat aaatcatata
     2761 tcgcaagcca ttgtccagtt gcccggtaat taacttttca tcctgcggta aggcggcggc
     2821 aatcagccgc cctgggagca acagagttgc cactaacgtc agtaagaaac agaggtttct
     2881 cataattatc tccatgcgaa aaccgggcga atttacccgg ttaagtaaaa tccgaactat
     2941 taaaatttca tgctgacatc aagccagaaa gtacggccac tggcgtaggt cgccacaccg
     3001 gtattcgttg tatcaacagc ggttttgcta tccagtacat tgagaatatc ggcactgatc
     3061 gtcaggtttt gttgtttcag aaattgtggc gtccaggaca agcgggtgtc ccaggtcagg
     3121 ctgctatcca gtttttcgtc aacatactgc ttgtaatctg aatattcgct gatgtattgc
     3181 gcattcgtct tacccaggat aatgcgagct ttacgcgctt cttgccaggc cagcgtattc
     3241 gcccacacta acccgctcgg ttgatgcgtg aaatccatgt ttaaggagat ctttaatggg
     3301 ttattaaaat ctgccactgg aacactatcg taagaaacca gattaccgtt ataaaccacc
     3361 tggttatcac cggtattgct ctcctcataa ccattgttta acgacaagtt gcccttgctc
     3421 ttgatatagc taaagacaat ttgcgggtta atatctacct ggctgatatg caggggttcg
     3481 gccagttcaa aactgaggtt gaacgaatgc gttttggttt tgccgtcgtt gttatattca
     3541 gtaatggtgg ttttagtcgc gctgtcggta cgactgcttt tgctgatttg atcatgcgct
     3601 tcacggtaaa catagtttgc gcgcgcaata acgttcttac cgattttctg ctgcaatccc
     3661 attgccagtt catcgttata aggcgttttc aaatcctgat aacgcgtcag ggttttatta
     3721 cctgataccg attccgtcca gctattgcgg atatcacgta atcccatatc aagaatattc
     3781 ccgccatagt aacggttata acctgctgta atcattgagg tttgatcagc aaaaatatcc
     3841 cattccgtca taaagcgcgg ggagatattg tggtttgaca gatagttgtc atagtcatac
     3901 cgcacgccgg gcattaatga cacattacgc cagctaatgc gatccgccat atacagcgtg
     3961 tagttgtcaa ttcccaggct gcctttacct ttatggtaaa tggtatggtt agttttcttt
     4021 ccggcagcat taatcacata ggattcagac tggttatggc gttcagtcca cgcatcggaa
     4081 tagatgtatt ccgcgccgaa gtagggttga tgcgaaacat tacccacggc gaatttttgc
     4141 cagtccaggc gtgttttgaa ggtgtaatta tctacagcct gggaaatgtg tcctaatccg
     4201 ccacgggtgc aacgccctgt aatatcacca tatgtacatg aaagttcggt gtaccagatg
     4261 tcatgatcgt gacgggtata atcactaata tgatcccaac caacggtggt acgtagtttg
     4321 gcccatgcga gttgcgtatc catatcccat gccagaccat aggatttatt acccatttcg
     4381 cgatcagact gcgggaaggt gctggtatta taatcacggc tggagccggt atattttaag
     4441 gttaaatcgt gggtaaagcg gtcgctggca taccaggtaa atttgctcaa tgcagtatcg
     4501 ataacgtttt tatactgtgc ccgaccggcg acaatgccgt cattcgaaac ataatccgcg
     4561 cgggtgatat cagactggcg gcgcgataaa ccggcggtaa cgccaaagtt ttcagcgagt
     4621 tcctgattaa acgacaaggt ataaaagttc tttttaaaat ctggagagta ataagtactt
     4681 cctgaagaac cttgattaaa tgcgctcttg ttattctcat cgatatgcga tgttaaccag
     4741 tccgaacgcg tagtgcgata acccagtttc acgctgctat catcagcgtt gaagcgtttg
     4801 atctttgcat caattacccc gccattgaag cgaccgaatt caaccggcac aaaactgtca
     4861 taaagcgtca cattgtccag taagctgaca tcaagataat acccctgtga catcccgcta
     4921 atattggttg cactactggc atcggactca ttcgctggat tcaggttgtt agttgcacta
     4981 ataccgtcaa tcaaataggc attctgatag ggcgacgcac cgtgaataga gattttctcc
     5041 gggcgaatat ctccctggtt caacgaggta ctttgcgttg aatccatgcg taccgcaggg
     5101 ttggttctca gcagatcgct gatattgcca ttcccggtcg gtaaacgctc gatgctttca
     5161 ctggtgtaat gcgtgttgcc gtttacgggt acagggacag gagcatagac cgtcatctct
     5221 tcaaaaaaat gcatgtacat gtttttgtca tcgacggcct gcgccacatc agcgccacat
     5281 aaaatgacgc caggaataag aactcgcttc atttatttat atctccgtac agcagggctt
     5341 ttattgtttt tataaaaccg cgctaatgtc acaaatatca tctgccaggt tccagacacc
     5401 gggttgatgt gtaaccataa tgacgccgct tgtgggtagt ttttcacgca ctaaacgcag
     5461 taagcggata gcctcttgtt cctcaagatg agaggtagtt tcgtcaagaa atatccattt
     5521 cggacgtcgt aaaattaatc gcgccagggc gatacgttgt ttttcgccgc tggaaagaat
     5581 atctccccag cgatcgtggt catgaatacg cgcagccaat ttccccagac caacctgatg
     5641 cagtacttcg ctcaacgatt tatcgtctac gggcagggga agtgctttac aaataatctc
     5701 tttcagtaag ccggttttga ttaacggtgt ttgtgacaca taccaactgt cagcaggaga
     5761 agaaatatca cctttaaacc acggccagca gtgggataat gttttaagca gtgtggtttt
     5821 tcccgcacca gagtaacctt tcagtaatag ccatttgcct ggcgaaacat gaaagttcag
     5881 gttctctaat atgatcttat tatcaggagt acgaatactc gcgtcagcca cttgtaccgc
     5941 atgttggcaa tttttaggct tattcgtagg gcgctgttcg gtgagttgat ggaactcata
     6001 caagcgatcg ataaccgcag ccagttcagc aagttcatca tatttataaa taaaccagct
     6061 taaattgttc gataccagca taaatgcctg gcgcgatttc atcagtccgc ccaaattgat
     6121 ctgcccgcta ataaactgcg gcaataacag aaagtaggga agaacgctaa gcgagcgcga
     6181 ataaatattc tgccagtaat caagccaccg ctgacgattc attaaacgat gccagttctc
     6241 tttaatggta tgaaaattgt cgctcaactc ctggcgttgt agagactcag cattgcttag
     6301 cgcaatcagt tctgcctgct tattatgctg cacaagattt gttcgaaatg tcgcttcgct
     6361 acgttgtttt tccacattaa gcggacgaat acgtttaccc accttatggg taaataaagt
     6421 tccaccgatc acaatgagca caacggtata gaccatatac ccctggatat tccattctgt
     6481 tccaccaaca gtgaatgaga gcgtacccgc gctttgccaa agaataacgg taaaggtgat
     6541 cagcatgcta agtgactgga tgaagccaaa tgaaaggctg agcgttttgc tgatcagtaa
     6601 gagaatgtct tcagcgatac gttggtcagg gttatctgta tttttatgct caccgtagat
     6661 ctgcgtgaag tagtagtttt tatctgcaaa ccagcgatta aggtagtaat ctgttaacca
     6721 ttcgcgccag cgaatagtca gtagtttaat taaccatgtt ttgtttacgg atattaatac
     6781 aaagatcccc agcagggcag ggaaccaaag gacaagctgc caaagcttat cggtttcttt
     6841 ctggcttagc gcattgaaaa aatcattatt ccagtcgttt aaccagacct gaattttaac
     6901 cacgccaagg atcatggcga ggataataat gattaacaac actgaagttt tattattctt
     6961 acgcagccaa aagggcttca gcagacagag atactttgct atcaacatac aaaacgtaat
     7021 gggaatggtt atcattagcg aaaattgatt gtgccatcca atgattatct atggcaatga
     7081 tttactgatg aaatttattt aagtatcatt taacaatatg aaatat
//
LOCUS       DAPHKZ010000187         7100 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.188, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000187 DAPHKZ010000000
VERSION     DAPHKZ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7100
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.188"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            39..224
                     /locus_tag="RH288_004297"
     CDS             39..224
                     /locus_tag="RH288_004297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033278.1"
                     /translation="MSRRYSSATITLVILFCRRPHCRKISVRQYYQKRVIFYPTTLQR
                     TACKKCLFLMRDIIISS"
     gene            185..304
                     /locus_tag="RH288_004298"
     CDS             185..304
                     /locus_tag="RH288_004298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDV4033279.1"
                     /translation="MPLSYAGYHHFIMMSLVSGEHNTPALSLQDESPGLVPAG"
     gene            339..682
                     /locus_tag="RH288_004299"
                     /pseudo
     CDS             339..682
                     /locus_tag="RH288_004299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(1054..1320)
                     /gene="minE"
                     /locus_tag="RH288_004300"
     CDS             complement(1054..1320)
                     /gene="minE"
                     /locus_tag="RH288_004300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDV4033280.1"
                     /translation="MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK"
     gene            complement(1324..2136)
                     /gene="minD"
                     /locus_tag="RH288_004301"
     CDS             complement(1324..2136)
                     /gene="minD"
                     /locus_tag="RH288_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDV4033281.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGV
                     AKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            complement(2160..2855)
                     /gene="minC"
                     /locus_tag="RH288_004302"
     CDS             complement(2160..2855)
                     /gene="minC"
                     /locus_tag="RH288_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDV4033282.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLK
                     HAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGK
                     EKAPRPAPTPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIAD
                     GNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARL
                     QLVENALTVQPLN"
     gene            3375..3743
                     /locus_tag="RH288_004303"
     CDS             3375..3743
                     /locus_tag="RH288_004303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgJ family protein"
                     /protein_id="HDV4033283.1"
                     /translation="MNMMRIFYIGLSGVGMMFSSMASGNDAGGLQSPACGVVCDPYIC
                     VNSDGISPELTRKYLGEKAAENLQSLQGYDPSEFTFANGVFCDVKEKLCRDDRYFGVD
                     GKRSGKINQTTTKMLFMCRE"
     gene            complement(3846..4247)
                     /locus_tag="RH288_004304"
     CDS             complement(3846..4247)
                     /locus_tag="RH288_004304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inhibitor of g-type lysozyme"
                     /protein_id="HDV4033284.1"
                     /translation="MKIKSIRKAVLLLALLTSTSFAAGKNVNVEFRKGHSSAQYSGEI
                     KGYDYDTYTFYAKKGQKVHVSISNEGADTYLFGPGIDDSVDLSRYSPELDSHGQYSLP
                     ASGKYELRVLQTRNDARKNKTKKYNVDIQIK"
     gene            4489..4782
                     /locus_tag="RH288_004305"
     CDS             4489..4782
                     /locus_tag="RH288_004305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HDV4033285.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMIL
                     PLDGRKKLVNADIEKVKQALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK"
     gene            4854..5513
                     /locus_tag="RH288_004306"
     CDS             4854..5513
                     /locus_tag="RH288_004306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDV4033286.1"
                     /translation="MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLF
                     IKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDL
                     TLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLSLSVNGEQRQQG
                     TTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRV
                     L"
     gene            5605..6051
                     /locus_tag="RH288_004307"
     CDS             5605..6051
                     /locus_tag="RH288_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HDV4033287.1"
                     /translation="MSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKDL
                     PAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ"
     gene            complement(6258..>7100)
                     /gene="hlyE"
                     /locus_tag="RH288_004308"
     CDS             complement(6258..>7100)
                     /gene="hlyE"
                     /locus_tag="RH288_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin HlyE"
                     /protein_id="HDV4033288.1"
                     /translation="LDLYNKYLDQVIPWQTFDETIKELSRFKQEYSQAASVLVGDIKT
                     LLMDSQDKYFEATQTVYEWCGVATQLLAAYILLFDEYNEKKASAQKDILIKVLDDGIT
                     KLNEAQKSLLVSSQSFNNASGKLLALDSQLTNDFSEKSSYFQSQVDKIRKEAYAGAAA
                     GVVAGPFGLIISYSIAAGVVEGKLIPELKNKLKSVQNFFTTLSNTVKQANKDIDAAKL
                     KLTTEIAAIGEIKTETETTRFYVDYDDLMLSLLKEAAKKMINTCNEYQKRHGKKTLFE
                     VPEV"
BASE COUNT         1829 a         1565 c         1686 g         2020 t
ORIGIN      
        1 gataatctga tttatcaata ttattgtgtg atttttatgt gagcagaaga tattcatcag
       61 caacgattac attagtcatt ttattttgcc gacggcctca ttgtcgaaag ataagcgtac
      121 gacagtatta tcagaaaaga gtgatttttt atccaactac acttcagcgc actgcgtgta
      181 aaaaatgcct ctttcttatg cgggatatca tcatttcatc atgatgtctt tggtgagcgg
      241 tgaacacaat acacctgcgc tgtctcttca ggatgaatcc cctggtctgg tgcctgcggg
      301 ctgatgttgc agcagagctt aggtcactta gacgctacta tcatttatcc aatggcatgg
      361 aatcgaaatc agtcgatacc cgcagtatat atcgtgaact gggtgcaacg ctgagttaca
      421 acatgcgcct ggggaacggt atggaaatga accctggctg aaggcggctg tgcgcaaaga
      481 atttgtcgat gataaccggg tgaaggtgaa taatgacggt aatttcgtca atgatttgtc
      541 gggcagacgt ggaatatacc aggcagctat taaagcctca ttcagcagta cgtttagcgg
      601 acatctcggg gtggggtata gccatggtgc cggtgtggaa tccccgtgga acgcggtggc
      661 tggtgtgaac tggtcgttct gaccatcaac gattaaactg cgcttcggcg cagttttcgt
      721 ttacaggatg ttgaaaggga aaattctggg gcaaaaaaag cccgccagtt acggcgggaa
      781 acctcatcct atgggagaac aatgaataat gaaattgcgg ggttatcatc tcccagtata
      841 tccatactaa caataaggtt atttactcaa ccaggcataa acattttgtt ttgtgcgtgg
      901 gaacagcctt aaggtgtaaa gggggaggtg gaaatagcaa tgaggagtat cagcaagaat
      961 actcgccgct ttaccacaac gtggatgaga gggatgaaaa actcaaggca gagataactc
     1021 tgccttgaag ataaatgcgc ttttacagcg ggcttatttc agctcttctg cttccggtaa
     1081 ggtcacgttc agctcaagaa tagaaatatc gccatctttt tgctcaagct gtacggttac
     1141 catctcagga tcaatttgta cgtatttaca aatgacctca agaatatctt tacgcaactg
     1201 cggcagataa tgcggttctg catcgctgcg acggcgttca gcaacaataa tctgcagccg
     1261 ttcttttgca atgttggctg tgtttttctt ccgcgagaga aagaaatcga gtaatgccat
     1321 aacttatcct ccgaacaagc gtttgaggaa gcctttcttc tcttcttcaa tgaagcggaa
     1381 aggacgttct tctcccaaca gacgttctac ggtatctgcg taggctttac ccgcatcggc
     1441 gttaatgtcg agaatgaccg gttcaccctg gttagaggcg cgcaatactg attgatcctc
     1501 tgggatcacg ccgacgagtt tgatgcgcag gatctccagc acatcttcca tgctcagcat
     1561 gtcacctctg cttacgcggc ctgggttata gcgcgttaac agcaggtgct ctttaatagg
     1621 ctcttcgcca ttttctgcgc ggcgtgattt cgacgccaga atgcctaaaa tacggtcaga
     1681 gtcgcgtact gaggagactt ccgggttggt ggtaataatg gcttcgtctg caaaatagag
     1741 tgccattaac gcaccggttt caatccctgc cggggagtca caaacgataa attcaaaatc
     1801 catcgctttc agatcatcaa gaactttggc gaccccttca cgggtgaggg catctttatc
     1861 gcgtgtttgc gatgccggca gaatatagag attttcagta cgcttatctt taattaacgc
     1921 ctgatttagc gttgcatcgc cctgaatgac gttgacgaaa tcgtaaacga cccggcgttc
     1981 acaacccata atcaggtcga gattacgcag gccgatatca aaatctatca cgacagtttt
     2041 ctttcccttc tgggccaaac cagtggcgat ggccgcgctg gaggttgtct taccaacacc
     2101 ccctttgccc gaagtaacaa caataatgcg tgccatagaa attccttgtt aaaaagggat
     2161 caatttaacg gttgaacggt caaagcgttt tcgactaact gcagtcgcgc cgctttgcca
     2221 taaaattctg ctgggatttg atcactcagc cagtattcac ctgcgatgga caccagttcc
     2281 gccatcaggt tcgtacaaaa tatttgcgtt tcccggtcac cacttgcccc tgccagcgca
     2341 cgaccgcgca tcatgccata gacatgaatg ttcccatcgg caatcaattc ggccccagcg
     2401 ctaacgtggc ttgtaacaat cagatcacat tgtggagcat aaatacgctg accggaacgc
     2461 accggggtat ctattaaacg cgtttttgtg accggcgttg tattttgcgc tggagcctgc
     2521 ggtgtgggag ctggacgtgg cgctttttcc tttccttccg tcaggatagg cagccccatc
     2581 ttttcaattt cggctttaag ttgcgcatct ttgcagccac ttacgccaat aacccgcaaa
     2641 ccggttgccg aaaccgcctt atgcatcgct gaccagttta ccgggtcttc cagtgcactg
     2701 acgttgagta caacgggggc atgttttaaa aatgcggggg cctgagcgat tttgtcttcc
     2761 agcgcctgat ggataacctt aggttctgcc tcatgcagat gaaccacaga taaagtgaag
     2821 ctactgcctt taagctcgat tggcgtgttt gacatcctgg ccttactcaa ttagctatta
     2881 atcatcgcca gcgcgcgatg atgttccgaa gactataagg catgttatag tctggattat
     2941 attgaggcaa gtcaccctcc catttattca gagtaaaagt ctattctgtg ataaatggcg
     3001 ctgattcata gcttaaaaaa tacccttgtc aatcaaccca ttgccgtcgt acttttgatt
     3061 gttcttattt acgcttcctt tttccgcacc ctaatcgtga cagcatctcc agacctgttt
     3121 aaatatccag tattgaggca agtgtatttt ttcaccacgc caggctttct taactttcca
     3181 ttttttgcgg catcattaaa gaacagatac ccgttatctt aatatccgcc acagaattgc
     3241 tctatcatag aaaccgcaga agacgtctga tacttctgtc aggtcatcgt aactcgtcca
     3301 ggtcagcggt tttgattacg gattgatgat gaaatgagca taagtgttgt acggttggat
     3361 tatcaggatg tgctatgaat atgatgcgta ttttttatat cggattgtca ggtgtgggga
     3421 tgatgttctc atcaatggcg tctggaaatg acgctggcgg acttcaatct ccggcgtgcg
     3481 gcgttgtttg cgacccgtat atttgtgtga actcagatgg catttcccca gagttaacaa
     3541 ggaaatatct cggcgaaaaa gccgctgaaa acttacaatc attacaaggc tacgatccca
     3601 gcgaatttac attcgctaac ggtgtatttt gcgatgttaa agaaaaatta tgtcgtgatg
     3661 atcgttattt tggtgtggat ggtaagcgga gtggaaaaat caatcaaacc accacaaaga
     3721 tgttatttat gtgtcgtgag tgatgtcttg tttacattat gttctattcg tcattaacct
     3781 cttgagcgac agagaggagt ggggcattaa cgtttatgac ggggagagtc cccgtcggtt
     3841 gacatttact taatttgaat atcgacgtta tattttttag ttttgttttt acgggcgtcg
     3901 tttcgggttt gcaacactcg cagctcatat ttgccagaag cagggagtga gtattgtccg
     3961 tgactatcga gttctgggga atatctggat aaatcaactg aatcatcgat tcctggcccg
     4021 aagaggtaag tatcagcgcc ttcattagag atactcacat gcactttctg accttttttg
     4081 gcatagaagg tatatgtatc gtaatcgtat ccctttattt cgccggagta ctgagcgctg
     4141 ctatggcctt ttctgaactc aacattgaca ttcttacccg cagcaaagct cgtggaggtt
     4201 agcagtgcaa gcagcaatac agccttcctg atgctcttga ttttcattgg tagtctcctg
     4261 ttcagaatga gtacgatgaa ctgttataat ataacaatcc ctaacgggag aattccagtg
     4321 gctttcctgc gttcggtaaa atcacgttgc ggcatttttg ccggggggat tacttataaa
     4381 gggggcatgg actcaacaaa ccgtagaaat ctacagctgg ctggcttgtg gcgcgggttt
     4441 cattgatgtt agcttatgcc aaaacctggc atcttaaaga gtaaaagtat gttttgtgtg
     4501 atttatcgaa gcagcaagcg tgaccagacc tatttatatg tcgaaaaaaa agacgatttt
     4561 tcgcgtgttc ctgaggaact gatgaaaggt tttggtcagc ctcagttagc gatgattctg
     4621 ccgctggatg ggcggaagaa actggtcaat gccgatattg aaaaggttaa acaggcatta
     4681 accgagcaag gttactattt gcagttaccg ccaccacccg aagatttgct gaagcaacat
     4741 ctttccgtca tggggcagaa aacagacgac actaacaaat aaccgatatc cggcggtggc
     4801 attatctttg tcggcgcggg ttttcatatc cacgataagg tgaggggaac gttatgtatc
     4861 aacatcacaa ctggcaaggt gcgctgctgg attatccggt gagtaaagta gtctgtgttg
     4921 gcagtaacta tgccaaacat attaaagaga tgggcagcgc agtgcccgaa gagccagtgc
     4981 tgtttattaa accagaaacg gcactgtgcg atctgcggca gccattggcg atcccatccg
     5041 atttcggttc agttcatcat gaagtcgaac tggcggtgtt gattggcgcg acactgcgtc
     5101 aggctacgga agagcatgtc cgcaaagcca ttgccggtta tggcgtggcg ctcgatctga
     5161 cattgcgtga tgttcaggga aaaatgaaga aagccgggca gccgtgggaa aaggctaaag
     5221 cgtttgataa ctcttgtccg ctttccgggt ttattcccgc ggcggaattt accggcgacc
     5281 cgcaaaatac aacgctgagc ctgagcgtaa acggcgaaca acgccagcaa ggtacgactg
     5341 cggacatgat ccataaaatc gttccgctga tcgcttatat gagcaagttt tttaccctca
     5401 aggccggtga cgttgtgttg acaggcacgc ctgatggcgt cggcccgttg caaagcggtg
     5461 atgagctgac agtcactttc gatgggcatt ctttgacaac tcgcgttttg taatactttt
     5521 tgccgcctga aagcggcggc aaaacttgca tcgctgtgcc agactggtta taaggtgcgt
     5581 tttaacgtaa tggcggaaca cctgatgagc gatgtacctt tctggcaaag taaaaccctg
     5641 gacgaaatga gcgatgcgga atgggagtcg ttgtgtgatg gttgcggtca gtgttgcctg
     5701 cataaactga tggatgaaga caccgacgaa atctacttca ctaacgtcgc ctgtcgccag
     5761 ctcaatatta aaacctgtca atgtcggaac tacgaacgtc gtttcgagtt tgaacccgac
     5821 tgcattaaat taacccgtga aaatctgcca acattcgaat ggctgccaat gacctgcgct
     5881 tatcgtttgc tggcggaagg taaagattta cctgcgtggc atccgctact tactggttcg
     5941 aaagcggcaa tgcatggtga acgtatctct gtgcgtcata tcgcagtgaa agaatcagaa
     6001 gtgattgact ggcaggatca tatcttaaat aaacctgact gggcgcagtg ataaatttaa
     6061 tagatgctga tgggggcttt cttaatatac gtctggatgc tcgccatttc gtagccctgt
     6121 ttttgaaagc gctctgtcat aatgagagtt acccgatacc ttattatcaa caggtaactc
     6181 tcaatcttta aaaaacgtct gtgtttttaa atgtgataaa ccttatacct tgagtacatg
     6241 gagagaataa tcgcttatca gacttcaggc acctcaaaga gtgtcttttt accgtgtctt
     6301 ttctgatact cattacaggt gttaatcatt tttttggccg cttcttttag caaagaaagc
     6361 attaaatcat cataatcaac gtagaatctg gttgtttcag tttccgtttt tatctcaccg
     6421 atggcggcta tttcggtggt taatttcaat ttggcggcat cgatatcttt attcgcttgt
     6481 ttaaccgtgt tagacagggt ggtaaagaaa ttctgcacag attttaactt gttcttcaat
     6541 tctggaatca gttttccttc aactacgccc gcagcaatag aataggaaat gattaatcca
     6601 aatggaccgg cgacgacacc ggctgcggca ccggcatatg cttccttcct gattttatct
     6661 acctgtgact ggaaatagct gcttttttct gaaaaatcat tggttaactg gctatctaac
     6721 gccagcagtt tcccggaagc gttgttgaaa ctttgtgagc ttaccagcag ggatttttgc
     6781 gcttcattca gcttcgtgat gccgtcatcc agtaccttaa tgagaatgtc tttctgggcg
     6841 gatgctttct tctcattgta ctcatcaaat agcaaaatat acgctgcgag caattgcgtc
     6901 gcaacaccac accattcata cactgtttgg gttgcttcaa aatacttatc ctggctatcc
     6961 ataagtaagg ttttaatatc gccgactaaa acggaggctg cctgtgaata ctcctgttta
     7021 aagcgactta actcttttat ggtttcatca aaggtctgcc aggggatgac ctgatcgaga
     7081 tatttattat aaagatctaa
//
LOCUS       DAPHKZ010000188         7091 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.189, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000188 DAPHKZ010000000
VERSION     DAPHKZ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7091
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.189"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(241..726)
                     /gene="sixA"
                     /locus_tag="RH288_004309"
     CDS             complement(241..726)
                     /gene="sixA"
                     /locus_tag="RH288_004309"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HDV4033289.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQKVE
                     IERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVSAYLQALTNEGVAS
                     VLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGNGTFNWQMSPCNLKMAKA
                     I"
     gene            complement(929..3073)
                     /gene="fadJ"
                     /locus_tag="RH288_004310"
     CDS             complement(929..3073)
                     /gene="fadJ"
                     /locus_tag="RH288_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HDV4033290.1"
                     /translation="MEMTSAFTLNVRLDNIAVITIDVPGEKMNTLKAEFASQVRAIIK
                     QLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEALARQGQQLMAEIHALPI
                     QVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIG
                     VSTALEMILTGKQLRAKQALKLGLVDDVVPHSILLEAAVELAKKERPSSRPLPVRERI
                     LAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGEL
                     AMTPQSQALRSIFFASTDVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGIP
                     VRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYRGFAHRDLI
                     IEAVFENLELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSP
                     VEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIR
                     MLTQGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVV
                     SSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGTQGQGRISAPQVAERCVM
                     LMLNEAVRCVDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLA
                     TQYGSRFTPCERLVEMGARGESFWKTTATDLQ"
     gene            complement(3073..4383)
                     /gene="fadI"
                     /locus_tag="RH288_004311"
     CDS             complement(3073..4383)
                     /gene="fadI"
                     /locus_tag="RH288_004311"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HDV4033291.1"
                     /translation="MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
                     SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWS
                     DGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLT
                     DGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     SDLTLIDMHEAFAAQTLANIQLLGSERFAREALGRAHATGEVDDSKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE"
     gene            complement(4564..4848)
                     /locus_tag="RH288_004312"
     CDS             complement(4564..4848)
                     /locus_tag="RH288_004312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HDV4033292.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTL
                     AALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR"
     gene            5220..6560
                     /gene="fadL"
                     /locus_tag="RH288_004313"
     CDS             5220..6560
                     /gene="fadL"
                     /locus_tag="RH288_004313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416846.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HDV4033293.1"
                     /translation="MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSGRSLKADNIAPTA
                     WVPNMHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYR
                     LNNAWSFGLGFNAVYARAKIERFAGDLGQLVAGQIMQSPAGQTQQGQALAATANGIDS
                     NTKIAHLNGNQWGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLNRAFNNYG
                     LPIPTATGGATQSGYLTLNLPEMWEVSGYNRVDPQWAIHYSLAYTSWSQFQQLKATST
                     SGDTLFQKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRF
                     WLSAGTTYAFNKDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF"
     gene            6926..>7091
                     /locus_tag="RH288_004314"
     CDS             6926..>7091
                     /locus_tag="RH288_004314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033294.1"
                     /translation="MLPSISINNTSAAYPESINENNNDEVNGLVQEFKNLFNGKEGIS
                     TCIKHLLELIK"
BASE COUNT         1802 a         1881 c         1656 g         1752 t
ORIGIN      
        1 ttttctccat tatctgtatt aataaatgat aatgagtgtc aaacagacat tattcatttc
       61 aacatgtaac tttgggcaaa atcaagatac gcgcagaaga atactttccg aatgaaagtt
      121 aaaggtgttt tatttataga tggggagagt cttcgatagt agtgaggttg acagatatcc
      181 gctgcctgat gagcaattat gcccaatgaa tctacctcat tgggcataat ttggaactca
      241 tcagatagct tttgccatct tcagattaca cgggctcatc tgccagttga atgtgccgtt
      301 tccgctttca tcaagcgtta cgctggcaat ggccgaggtg gtaaacatag gcggcgtttc
      361 gcccggacat aactcggcaa ccagataccc gactaacggt aagtgagaga tcaccagtac
      421 cgaagcaaca ccttcattgg tcaacgcctg caaataggca ctgaccagac caacatcgcc
      481 gcagggcgtt aactccggca gaacttctgc actggaaggc aggttcagac aatcccctac
      541 ttcttccagt gtttgctcgg ctcgcaggaa cgggctcacc agaacgcgtt cgatttccac
      601 tttttgacct ttcagccagt tcgccatcag gcgagattcg tcacaaccat tagtggtcag
      661 aggacgaacg gaatcactgg cggcatcgag ggctgcgtcg ccgtgacgca tgataaaaac
      721 ttgcatattg caccgctttt gttaaccaga ttcgcccgtt ttctttcatc tgaaaccaga
      781 gaaagaaaac ggtggccggc attgtgcctt atccattcac cgaatgaaac gctgtttttt
      841 acctcaatgg cgtaagtata gtcaatatgc gtttacattt tgaccaacac tccgccattc
      901 agcgcggatt catatagctt tgaccttctt attgcaggtc agttgcagtt gttttccaaa
      961 aactttcccc acgcgcgccc atctcgacca aacgctcgca aggggtaaaa cgggaaccat
     1021 actgcgtggc aagtcgttgc attattgcaa ccacttcgcc cgcgccgaga gaatcgatat
     1081 agcggaacgg tccaccgaga aatggcggaa aaccaatgcc aaataccgcg ccaatatccc
     1141 cgtcacgcac gctacggata acctgctcat caacacaacg tactgcttca ttcagcatca
     1201 acatcacaca ccgttcagca acctgcggtg cggagattcg cccctgccct tgtgtgccaa
     1261 tcagcgggta aatggcggga tcgacctgtt ttttgctttt acgccctttc tgaccataaa
     1321 gatagaaacc ccggccattt tttctgcctt tgcgatcgtc gttcaaaatt gaagaaacaa
     1381 catttgcagg cgcgctaaaa cgttctccat aagcggcttc cagtacagga ataattttag
     1441 tcccggtgtc gattcctacc tcatccaaaa gttggattgg gcctaccgga aaaccaaatt
     1501 tcactagcgc ggcatcaatg tgctctaccc gttcaccttg ggtcaacatg cggatagctt
     1561 cattaatgta aggcgctaag atgcgattga cgtaaaaacc ggctttgtca cgcacgacaa
     1621 ttggcgtttt accctgtttt ttcgccagtt ttactgtggt agcgatggtt tgcgccgatg
     1681 tccccgcatg aggaataatc tccaccagcg gcattttttc caccggactg aagaaatgca
     1741 ggccgataac ttgctcaggt cgcgtggcgt gagcggcgat atcaccaatc ggtaaagatg
     1801 acgtattcga agcaaagatg gtatgagcgg cgcaattttg ctcaacttcc gccaccatct
     1861 gttgtttcaa ttcgagattt tcaaacaccg cttcaataat cagatcgcga tgggcaaagc
     1921 cgcgatagtc cgtcgttccg gagattaatg ccagctgttt gtcacgttcg ctggctttga
     1981 gatgacgacg gcgaactttg ccctccagct gatcccaact gtacttcagc gcatgattta
     2041 tgccctgcgg gttgatatct ttaattctga ccggaatccc cgctttacaa gcagtgacat
     2101 aagcaatacc gccgcccatc aagccaccac ctaaaatccc cacgctgttt aatggcgcag
     2161 gcggcgcatc actgccggga tctttcttca cgtccgtact ggcaaaaaag atactacgca
     2221 gcgcctgcga ttgtggcgtc atcgccagtt cgccaaacgc ccgagcttcg gcgtcataac
     2281 cgctgctggt gccctgcgct aatcccgttt caacaacctc caggatgcgt tctgtcgccg
     2341 gataattgcc ttgagttttg tgttctgttt tcttgccgac cattttgaac agcagcgcac
     2401 gacctaacgg ccccgccaga atacgctcgc gtacaggtag agggcgggaa gatgggcgct
     2461 ccttctttgc cagctcaaca gcggcttcca gcagaatgga gtgcggaaca acgtcatcca
     2521 ccagccccag ctttaatgcc tgtttcgccc gaagttgttt tccggtgagg atcatctcta
     2581 atgctgtgct gacgcctatc agacgcggta aacgctgggt gccgcctgaa ccgggtaaca
     2641 atccaagttg tacttcaggc aaaccgagca ccgttttagg atcgtcagta caaacgcgac
     2701 cgtggcacgc cagcgccaac tccagcccac cacccaggca agcgccatga atagccgcga
     2761 taacctgaat gggcaaagca tgaatctccg ccatcaactg ttggccctgc cgcgccagag
     2821 cttccgcttc ttgcgccgtt ttgcagttgc cgatcatgtt gatgtctgcg ccagcaatga
     2881 agttgtccgg tttagcggag acaaacacca cgcctcgcaa ctctttgttt tcacggagtt
     2941 gcttaataat ggcgcgcacc tgcgaggcaa actccgcctt cagggtattc attttctcac
     3001 ccggtacgtc gatggtgata acggcaatgt tgtccagacg aacattaagg gtaaacgctg
     3061 atgtcatttc cattattccg cctccagaac cattgccgcg ccaagcccac cggcagcaca
     3121 ggcggtaact aaaccaaatc caccgccgcg acggcgaagt tcatgcaatg tctgggtaat
     3181 catccgcgcg ccggtcgccg cgaagggatg cccgtaagca atcgaaccgc caagcacgtt
     3241 aaatttgcta tcgtccactt cgccagtggc atgtgcacgc cccagtgctt cacgagcaaa
     3301 acgttcacta cccagcaact gaatattcgc cagcgtctga gctgcaaagg cttcgtgcat
     3361 atcgatcaat gtcagatcgc tcatcgtcaa accggcacgc tccagcgcca gcggtgttga
     3421 ccaggctgga ccgagcaaca tgtcctgcca gacatcaatc gcagtaaatg cgtagctgcg
     3481 cagatacccc agcggcacca gccctaattc tttcgcccgg gattcagtca tcaggatcac
     3541 cgctgccgcg ccatcggtca gcggcgtact gtttgccgcc gttaccgttc cgtgtttgcg
     3601 atcaaacgcc gggcgcagct ttgcgtaatc ggcaagcgag gaattaccgc gaatattgtt
     3661 gtcttcgaca agcggttgtt tataaggagg gataaaggca gtcatcacct cttctttgag
     3721 ttttccgtct gaccatgcct gagcggcacg ctgatgcgaa cggtgcgcta atgcatcttg
     3781 ctgttctcgg gtgatgccgt aggttttcgc catttgctct gcggtgtcgc ccatccgcaa
     3841 gccggtagaa tattctgcta ccgcaggtgg tacgggcatt aagtcgcgca aacgcaggcg
     3901 agagaagagt ttcagtcgct ggctcatggt acgagctttg ttgacatcaa ccagcacgcg
     3961 cgccagtttt ttactgacgc caattggcaa taccgaagag gaatctgccc caccggcaat
     4021 ccccgctcga atagttcccg ccatcaggct ttctgcgacg tttgcaactg cctggaaact
     4081 ggtagcgcaa gcgcggctga cgctgtaagc atcggtatgt acattcattc ccgtaccgag
     4141 aacaatttca cgcgcaatgt tgggggcttc aggcatttgt acgacctgac caaagaccag
     4201 ttgttcaatc acttcggcgg ggatctcgct gcgtgccagc agttcgccta ccaccatctt
     4261 ccctaaatca accgcgggaa tgccatgaaa agccgtcgcc tgacgggcaa aaggcgtacg
     4321 taaaccgcta acaatggcga tacgatcgcc ctggcgggta accagcggta aaacctgacc
     4381 cataacactc ccctgtaaaa aaataaataa agtggtctga cctgatcata gtcttaacca
     4441 tttttttaca tttagccaag tggagaaaag ggaaagtggg agctatgaca cagagagaaa
     4501 agaagaagag aaaagaaaac gcccctgcca gcaactgaca ggggcgtacg tacccgagag
     4561 gaattaacgc agacccagct ggaaaatcag catttcagct tcgcaggcaa aagtgaaatc
     4621 gatatccagg cgcacaccgt cagactcttc agtgaaagtc ggggtgattt tgcaaggttc
     4681 agattccacg ctacgggctt tttcagtcag cgccgccagc gtttgctctg cttctgcgcg
     4741 gtttgcaaac acgcggctgt aagacgcggt gcagtcggag ttgtccataa tggtgccaac
     4801 atccatacag cagcaaaccg gggtttcatc agcactacat ttactcatcg ttgatttcct
     4861 ctgtatgtgc acccaaggtg ccagataaac gttgtggata ttttacgctt ccggaaagtg
     4921 ctgctccagt tgttaattct gcaaaatcgg ataagtgacc gaaatcacac ttaaaaatga
     4981 tctaaaacaa aattcacccg aatccatgag tgcgccacct ccaaattttg ccagctggat
     5041 cgcgtttctt agatcatatt tgaaaaaaga tagaaacata cttgcagcat tccagctggt
     5101 ccgacctata ctctcgccac tggtctgatt tctaagatgt acctcagacc ctacacttcg
     5161 cgctcctgtt acagcacgta acatagtttg tataaaaata aatcattgag gttatggtca
     5221 tgagccagaa aaccctgttt acaaagtctg ctctcgcagt cgcagtggca cttatctcca
     5281 cccaggcctg gtcggcaggc tttcagttaa acgaattttc ttcctctggc ctgggccggg
     5341 cttattcagg ggaaggcgca attgccgatg atgcaggtaa cgtcagccgt aaccccgcat
     5401 tgattactat gtttgaccgc ccgacatttt ctgcgggtgc ggtttatatt gacccggatg
     5461 taaatatcag cggaacgtct ccatctggtc gtagcctgaa agccgataac atcgcgccta
     5521 cggcatgggt tccgaacatg cactttgttg caccgattaa cgaccaattt ggttggggcg
     5581 cttctattac ctctaactat ggtctggcta cagagtttaa cgatacttat gcaggcggct
     5641 ctgtcggggg tacaaccgac cttgaaacca tgaacctgaa cttaagcggt gcgtatcgct
     5701 taaataatgc atggagcttt ggtcttggtt tcaacgccgt ctacgctcgc gcgaaaattg
     5761 aacgtttcgc aggcgatctg gggcagttgg ttgctggcca aattatgcaa tctcctgctg
     5821 gccaaactca gcaagggcaa gcattggcag ctaccgccaa cggtattgac agtaatacca
     5881 aaatcgctca tctgaacggt aaccagtggg gctttggctg gaacgccgga atcctgtatg
     5941 aactggataa aaataaccgc tatgcactga cctaccgttc tgaagtgaaa attgacttca
     6001 aaggtaacta cagcagcgat cttaatcgtg cgtttaataa ctacggtttg ccaattccta
     6061 ccgcgacagg tggcgcaacg caatcgggtt atctgacgct gaacctgcct gaaatgtggg
     6121 aagtgtcagg ttataaccgt gttgatccac agtgggcgat tcactatagc ctggcttaca
     6181 ccagctggag tcagttccag cagctgaaag cgacctcaac cagtggcgac acgctgttcc
     6241 agaaacatga aggctttaaa gatgcttacc gcatcgcgtt gggtaccact tattactacg
     6301 atgataactg gaccttccgt accggtatcg cctttgatga cagcccagtt cctgcacaga
     6361 atcgttctat ctccattccg gaccaggacc gtttctggct gagtgcaggt acgacttacg
     6421 catttaataa agatgcttca gtcgacgttg gtgtttctta tatgcacggt cagagcgtga
     6481 aaattaacga aggcccatac cagttcgagt ctgaaggtaa agcctggctg ttcggtacta
     6541 actttaacta cgcgttctga taacgcgttc gcctggataa agtcacctgc atagcaggtg
     6601 actttaactc ccccacttca ccgaaagtag tgtcctcatt gcttacctcc tgagttttgc
     6661 aaacagcctg ttggcagctt gccctttcaa atcaataagc ggtatccaca gacaaacctg
     6721 aagggaaagg catattttca ggcgttctgc tcgtccttct caaagagttt acttttctgc
     6781 atttccagga tactcccccc ccctggctat tgtgcgctca tacactcaaa ttaaagatag
     6841 gttctaaata aatgagcgtt ttttgatagt ctatttcatt aggtaatata tatttgtaac
     6901 aaatcaatca aaatggaata aaatcatgct accatctatt tcaatcaaca ataccagcgc
     6961 agcttaccca gaatccatca atgaaaataa caatgatgaa gttaatggat tagtacaaga
     7021 gttcaaaaac ctttttaatg gtaaggaagg aataagcacc tgtattaaac atctacttga
     7081 gcttataaaa a
//
LOCUS       DAPHKZ010000189         7079 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.190, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000189 DAPHKZ010000000
VERSION     DAPHKZ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7079
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.190"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            587..1576
                     /gene="araF"
                     /locus_tag="RH288_004315"
     CDS             587..1576
                     /gene="araF"
                     /locus_tag="RH288_004315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter substrate-binding
                     protein AraF"
                     /protein_id="HDV4033295.1"
                     /translation="MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEW
                     KFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKAR
                     GYDMKVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAV
                     MAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPE
                     VKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLL
                     PSPDVHGYKSSEMLYNWVAKDVEPPKFTEVTDVVLITRDNFKEELEKKGLGGK"
     gene            1646..3160
                     /gene="araG"
                     /locus_tag="RH288_004316"
     CDS             1646..3160
                     /gene="araG"
                     /locus_tag="RH288_004316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter ATP binding protein
                     AraG"
                     /protein_id="HDV4033296.1"
                     /translation="MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGA
                     GKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAEN
                     IYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
                     NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKD
                     GRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPIS
                     LAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMM
                     LCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPG
                     AEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGV
                     AVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA"
     gene            3175..4161
                     /gene="araH"
                     /locus_tag="RH288_004317"
     CDS             3175..4161
                     /gene="araH"
                     /locus_tag="RH288_004317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter permease AraH"
                     /protein_id="HDV4033297.1"
                     /translation="MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPN
                     FATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESL
                     WIGVAAGLLLGVLCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
                     SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVV
                     RTKIIIFVLSGLVSAIAGIILASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKI
                     SYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYKQKAKRTV"
     gene            4328..5128
                     /gene="otsB"
                     /locus_tag="RH288_004318"
     CDS             4328..5128
                     /gene="otsB"
                     /locus_tag="RH288_004318"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HDV4033298.1"
                     /translation="MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDNILQG
                     LQLLATASDGALALISGRSMVELDALAKPYRFPLAGVHGAERRDINGKTHIVHLPDAI
                     ARDISVQLHTVIAQYPGAELEAKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
                     QGKCVVEIKPRGTSKGEAIAAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVK
                     IGTGATQASWRLAGVPDVWSWLEMITTALQQKRENNRSDDYESFSRSI"
     gene            5103..6527
                     /gene="otsA"
                     /locus_tag="RH288_004319"
     CDS             5103..6527
                     /gene="otsA"
                     /locus_tag="RH288_004319"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HDV4033299.1"
                     /translation="MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSG
                     ETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPA
                     WDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
                     PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKA
                     FRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLA
                     YEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLY
                     YLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAA
                     NELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISD
                     LKQIVPRSAESQQRDKVATFPKLA"
     gene            complement(6534..6962)
                     /gene="uspC"
                     /locus_tag="RH288_004320"
     CDS             complement(6534..6962)
                     /gene="uspC"
                     /locus_tag="RH288_004320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HDV4033300.1"
                     /translation="MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPE
                     MYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHH
                     FDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD"
BASE COUNT         1797 a         1644 c         1833 g         1805 t
ORIGIN      
        1 caatgtaact gcaatgaatt ttaatgatag tgctttttgt atcttgttga tattaatcaa
       61 tgaatttgaa ttcatgatga agtgatgatt ttataaaacg ttttttcatt tttgcgagat
      121 ggctctcatt atacgtgttc tgttaattaa tgagcacagt gataattaat gacgaaatga
      181 atgacgtgca ttttccacat ctttgagttg cggttattac accatttcaa aaactcaacg
      241 ccaggtaatg cggcctattg actggttaaa aagaagacat cccgcatggg taccaaagac
      301 aacaaggatt tccaggctaa tcttatggat taatctgctg tgcattcgac aatttgtctg
      361 acaaattggc tttcccttat gtcttttccc gctaaattta tgcacgttct cactgtaatt
      421 ctgcgatgtg atattgctct cctatggaga attaatttct cgctaaaact atgtcaacac
      481 agtcacttat cttttagtta aaaggtaatg ctttgttttc cgattaattt aacgaatgtc
      541 attcgttttt gccctacaca aaacgacact aaagctggag agaaccatgc acaaatttac
      601 taaagccctg gcagccattg gtctggcagc cgttatgtca caatccgcta tggcggagaa
      661 cctgaagctc ggttttctgg tgaagcaacc ggaagagccg tggttccaga ccgaatggaa
      721 gtttgccgat aaagccggga aggatttagg gtttgaggtt attaagattg ccgtgccgga
      781 tggcgaaaaa acattgaacg cgatcgacag cctggctgcc agtggcgcaa aaggtttcgt
      841 tatttgtact ccggacccca aactcggctc tgccatcgtc gcgaaagcgc gtggctacga
      901 tatgaaagtc attgccgtgg atgaccagtt tgttaacgcc aaaggtaagc caatggatac
      961 cgttccgctg gtgatgatgg cggcgactaa aattggcgaa cgtcagggcc aggaactgta
     1021 taaagagatg cagaaacgtg gctgggatgt caaagaaagc gcggtgatgg cgattaccgc
     1081 caacgaactg gataccgccc gccgccgtac tacgggatct atggatgcgc tgaaagcggc
     1141 cggattcccg gaaaaacaaa tttatcaggt acctaccaaa tctaacgaca tcccgggggc
     1201 atttgacgct gccaactcaa tgctggttca acatccggaa gttaaacatt ggctgatcgt
     1261 cggtatgaac gacagcaccg tgctgggcgg cgtacgcgcg acggaaggtc agggctttaa
     1321 agcggccgat atcatcggca ttggcattaa cggtgtggat gcggtgagcg aactgtctaa
     1381 agcacaggca accggcttct acggttccct gctgccaagc ccggacgtac atggctataa
     1441 atccagcgaa atgctttaca actgggtagc aaaagacgtt gaaccgccaa aatttaccga
     1501 agttaccgac gtggtactga tcacgcgtga caactttaaa gaagaactgg agaaaaaagg
     1561 tttaggcggt aagtaatttg ccggaaaaat tcccctctgc atgatgcaga gggggtgtga
     1621 acgaccagtg attcacggag acgttatgca acagtctacc ccgtatctct catttcgcgg
     1681 catcggtaaa acgtttcccg gcgttaaggc gctgacggat attagttttg actgctatgc
     1741 cggtcaggtt catgcgttga tgggtgaaaa tggcgcagga aaatcaactc tcttaaaaat
     1801 cctcagcggc aactatgcgc caaccacggg ttctgtagtg attaatgggc aggaaatgtc
     1861 cttttccgac acgaccgcag cacttaacgc gggcgtggcg attatttacc aggaactgca
     1921 tctcgtgccg gaaatgaccg tcgcggaaaa catctatctc ggccagctgc cgcataaagg
     1981 cggcattgtg aatcgctcat tgctgaatta tgaggcgggt ttacaactta aacatcttgg
     2041 tatggatatt gacccggaca cgccgctgaa atatctctcc attggtcagt ggcagatggt
     2101 tgaaatcgcc aaagcgctgg cgcgtaacgc caaaattatc gcctttgatg agccaaccag
     2161 ctccctctct gcccgtgaaa tcgacaatct tttccgcgtt attcgtgaac tgcgaaaaga
     2221 ggggcgggta atcttatacg tttctcaccg tatggaagaa atatttgccc tcagcgatgc
     2281 cattactgtc tttaaagatg gacgttatgt caaaaccttt accgatatgc agcaggttga
     2341 ccacgacgcg ctggtgcagg cgatggtcgg gcgcgacatt ggcgatatct acggctggca
     2401 accgcgtagt tatggcgagg agcgcctacg tcttgatgct gtgaaagcac caggcgtgcg
     2461 tacgccaata agtctggcgg ttcgcagtgg tgaaattgtt gggctgtttg gtctggtagg
     2521 ggcggggcgt agcgaattaa tgaaaggcat gtttggcggg acgcaaatca ccgccggtca
     2581 ggtttatatc gaccaacagc cgatcgatat tcgtaaaccg agccacgcca ttgccgcagg
     2641 catgatgctc tgcccggaag atcgcaaagc ggaaggcatt attcccgtgc actccgttcg
     2701 cgacaatatc aacatcagtg ccagacgtaa acatgtgctc ggcggttgtg taatcaacaa
     2761 cggttgggaa gaaaacaatg ccgatcacca cattcgttcg ctcaacatca aaacgccggg
     2821 cgcggagcaa ctgatcatga atctctcagg cggaaatcag caaaaagcca ttctgggccg
     2881 ctggttatcg gaagagatga aggtcatttt gctggatgaa cctacgcgcg gcattgatgt
     2941 tggcgctaag cacgaaatat ataacgtaat ttatgcgctg gcggcgcagg gcgtggcggt
     3001 gctgtttgcc tccagcgact tacctgaagt cctcggcgtt gccgaccgga ttgtggtgat
     3061 gcgggaaggt gaaatcgccg gtgaattgtt acacgagcag gcagatgagc gtcaggcact
     3121 gagccttgcg atgcctaaag tcagccaggc tgttgcctga gtaaggagag tatgatgtct
     3181 tctgtttcta catcggggtc tggcgcacct aagtcgtcat tcagcttcgg gcgtatctgg
     3241 gatcagtacg gcatgctggt ggtgtttgcg gtgctcttta tcgcctgtgc catttttgtc
     3301 ccaaattttg ccaccttcat taatatgaaa gggttgggcc tggcaatttc catgtcgggg
     3361 atggtggctt gtggcatgtt gttctgcctc gcttccggtg actttgacct ttctgtcgcc
     3421 tccgtaattg cctgtgcggg tgtcaccacg gcggtggtta ttaacctgac tgaaagcctg
     3481 tggattggcg tggcagcggg gttgttgctg ggcgttctct gtggcctggt caatggcttt
     3541 gttatcgcca aactgaaaat aaatgctctg atcacgacat tggcaacgat gcagattgtt
     3601 cgaggtctgg cgtacatcat ttcagacggt aaagcggtcg gtatcgaaga tgaaagcttc
     3661 tttgcccttg gttacgccaa ctggttcggt ctgcctgcgc caatctggct caccgtcgcg
     3721 tgtctgatta tctttggttt gctgctgaat aaaaccacct ttggtcgtaa caccctggcg
     3781 attggcggga acgaagaggc cgcgcgtctg gcgggtgtac cggttgttcg caccaaaatt
     3841 attatctttg ttctctcagg cctggtatca gcgatagccg gaattattct ggcttcacgt
     3901 atgaccagtg ggcagccaat gacgtcgatt ggttatgagc tgattgttat ctccgcctgc
     3961 gttttaggtg gcgtttctct gaaaggtggc atcggaaaaa tctcatatgt ggtggcgggt
     4021 atcttaattt taggcaccgt ggaaaacgcc atgaacctgc ttaatatttc tcctttcgcg
     4081 cagtacgtgg ttcgcggctt aatcctgctg gcagcggtga tcttcgaccg ttacaagcaa
     4141 aaagcgaaac gcactgtctg atgctttttt ctgcaacaat ttagcgtttt ttcccaccat
     4201 agccaaccgc cataacggtt ggctgttctt cgttgcaaat ggcgaccccc gtcacactgt
     4261 ctatacttac atgtctgtaa agcgcgttct gcgcaacaca ataagaaaag agaaggagga
     4321 gaaccgggtg acagaaccgt taaccgaaac ccctgaacta tccgcgaaat atgcctggtt
     4381 ttttgatctt gatggaacgc tggcggaaat caaaccgcat cccgatcagg tcgtcgtgcc
     4441 tgacaatatt ctgcaaggac tacagctact ggcaaccgca agtgatggtg cattggcatt
     4501 gatatcaggg cgctcaatgg tggagcttga cgcactggca aaaccttatc gcttcccgtt
     4561 agcgggcgtg catggggcgg agcgccgtga catcaatggt aaaacacata tcgttcatct
     4621 gccggatgcg attgcgcgtg atattagcgt gcaactgcat acagtcatcg ctcagtatcc
     4681 cggcgcggag ctggaggcga aagggatggc ttttgcgctg cattatcgtc aggctccgca
     4741 gcatgaagac gcattaatga cattagcgca acgtattact cagatctggc cacaaatggc
     4801 gttacagcag ggaaagtgtg ttgtcgagat caaaccgaga ggtaccagta aaggtgaggc
     4861 aattgcagct tttatgcagg aagctccctt tatcgggcga acgcccgtat ttctgggcga
     4921 tgatttaacc gatgaatctg gcttcgcagt cgttaaccga ctgggcggaa tgtcagtaaa
     4981 aattggcaca ggtgcaactc aggcatcatg gcgactggcg ggtgtgccgg atgtctggag
     5041 ctggcttgaa atgataacca ccgcattaca acaaaaaaga gaaaataaca ggagtgatga
     5101 ctatgagtcg tttagtcgta gtatctaacc ggattgcacc accagacgag cacgccgcca
     5161 gtgccggtgg ccttgccgtt ggcatactgg gggcactgaa agccgcaggc ggactgtggt
     5221 ttggctggag tggtgaaaca gggaatgagg atcagccgct aaaaaaggtg aaaaaaggta
     5281 acattacgtg ggcctctttt aacctcagcg aacaggacct tgacgaatac tacaaccaat
     5341 tctccaatgc cgttctctgg cccgcttttc attatcggct cgatctggtg caatttcagc
     5401 gtcctgcctg ggacggctat ctacgcgtaa atgcgttgct ggcagataaa ttactgccgc
     5461 tgttgcaaga cgatgacatt atctggatcc acgattatca cctgttgcca tttgcgcatg
     5521 aattacgcaa acggggagtg aataatcgca ttggtttctt tctgcatatt cctttcccga
     5581 caccggaaat cttcaacgcg ctgccgacat atgacacctt gcttgaacag ctttgtgatt
     5641 atgatttgct gggtttccag acagaaaacg atcgtctggc gttcctggat tgtctttcta
     5701 acctgacccg cgtcacgaca cgtagcgcaa aaagccatac agcctggggc aaagcatttc
     5761 gaacagaagt ctacccgatc ggcattgaac cgaaagaaat agccaaacag gctgccgggc
     5821 cactgccgcc aaaactggcg caacttaaag cggaactgaa aaacgtacaa aatatctttt
     5881 ctgtcgaacg gctggattat tccaaaggtt tgccagagcg ttttctcgcc tatgaagcgt
     5941 tgctggaaaa atatccgcag catcatggta aaattcgtta tacccagatt gcaccaacgt
     6001 cgcgtggtga tgtgcaagcc tatcaggata ttcgtcatca gctcgaaaat gaagctggac
     6061 gaattaatgg taaatacggg caattaggct ggacgccgct ttattatttg aatcagcatt
     6121 ttgaccgtaa attactgatg aaaatattcc gctactctga cgtgggctta gtgacgccac
     6181 tgcgtgacgg gatgaacctg gtagcaaaag agtatgttgc tgctcaggac ccagccaatc
     6241 cgggcgttct tgttctttcg caatttgcgg gagcggcaaa cgagttaacg tcggcgttaa
     6301 ttgttaaccc ctacgatcgt gacgaagttg cagctgcgct ggatcgtgca ttgactatgt
     6361 cgctggcgga acgtatttcc cgtcatgcag aaatgctgga cgttatcgtg aaaaacgata
     6421 ttaaccactg gcaggagtgc ttcattagcg acctaaagca gatagttccg cgaagcgcgg
     6481 aaagccagca gcgcgataaa gttgctacct ttccaaagct tgcgtaggag cggttaatct
     6541 cccgtaagtg gaactaacag cacatcgacc tcacttgagg caataactct tttcgccgag
     6601 caggatgctc gcgaaaagaa actgtgattg tgattaccgc aaatcaccaa atcgaaatga
     6661 tgcttgtgac atacttccag aatatgttcg cttaactcac cgtaggcaat aaacgtcttg
     6721 tcaacgggat accccgcatc ctgaattaac ttatcaagaa agctttgcgt ttcttcctgc
     6781 atcacgctgc gtaaatcttc aagcatcggc gcagctaatt gattgtacat ttccgggtcg
     6841 gaagcgagag taattaaact gatgtgtccc tttactggcc tggcgataga taccgctttt
     6901 gccagcagtt gctgactttc cggtgtaacc gcaacagcga caagaatatt gctatagctc
     6961 ataacctgtt ccttattctg tgaacttcag gtgacattaa agctttactc ctaatggaga
     7021 aacgacgcaa tcccaactcg gtcaaacagg taaatattag tctgattatt agtaaagac
//
LOCUS       DAPHKZ010000190         6951 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.191, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000190 DAPHKZ010000000
VERSION     DAPHKZ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6951
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.191"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(119..733)
                     /locus_tag="RH288_004321"
     CDS             complement(119..733)
                     /locus_tag="RH288_004321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HDV4033301.1"
                     /translation="MNIFEQTLPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNAAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     gene            1151..1840
                     /gene="paoA"
                     /locus_tag="RH288_004322"
     CDS             1151..1840
                     /gene="paoA"
                     /locus_tag="RH288_004322"
                     /EC_number="1.2.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase iron-sulfur subunit"
                     /protein_id="HDV4033302.1"
                     /translation="MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAATAVVYPH
                     STLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRTTLLDTLRENLHLIGTKKGCDHG
                     QCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGY
                     CTSGQICSSVAVLKEIQDGIPSHVTVDLVSAPETTADEIRERMSGNICRCGAYANILA
                     AIEDAAGEIKS"
     gene            1837..2793
                     /gene="paoB"
                     /locus_tag="RH288_004323"
     CDS             1837..2793
                     /gene="paoB"
                     /locus_tag="RH288_004323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidoreductase FAD-binding subunit
                     PaoB"
                     /protein_id="HDV4033303.1"
                     /translation="MKAFTYERVNTPAEAALSAQRVPGAKFIAGGTNLLDLMKLEIET
                     PTHLIDVNGLGLDKIEVTDAGGLRIGALVRNTDLAAHERVRRDYAVLSRALLAGASGQ
                     LRNQATTAGNLLQRTRCPYFYDTNQPCNKRLPGSGCAALEGFSRQHAVVGVSEACIAT
                     HPSDMAVAMRLLDAVVETITPEGKTRSITLADFYHPPGKTPHIETALLPGELIVAVTL
                     PPPLGGKHIYRKVRDRASYAFALVSVAAIIQPDGSGRVALGGVAHKPWRIEAADAQLS
                     QGAQAVYDTLFASAHPTAENTFKLLLAKRTLASVLAEARAQA"
     gene            2790..4988
                     /gene="paoC"
                     /locus_tag="RH288_004324"
     CDS             2790..4988
                     /gene="paoC"
                     /locus_tag="RH288_004324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidoreductase molybdenum-binding
                     subunit PaoC"
                     /protein_id="HDV4033304.1"
                     /translation="MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEE
                     APNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLGG
                     PTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
                     NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRT
                     DLAKTLKVPVENVRIISPYIGGGFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIP
                     NNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAVQQSELLYAGANRHT
                     GLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADP
                     TRCFSRRQLIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGAR
                     VHLEQNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSFPVSAGSGG
                     QWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEATAGGRL
                     TAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARS
                     QVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPIS
                     SPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPITLDKLLDKLPDVV"
     gene            4998..5954
                     /gene="paoD"
                     /locus_tag="RH288_004325"
     CDS             4998..5954
                     /gene="paoD"
                     /locus_tag="RH288_004325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor insertion chaperone PaoD"
                     /protein_id="HDV4033305.1"
                     /translation="MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAVLV
                     TLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGRDREIRYGE
                     GSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPVGLRYDPQAQSLVCLPTQ
                     TRTGWNLNGFEVGFRPCVRLMIYGRSLEAQATASLAAATGYDSHIFDLFPASASAQID
                     TDTAVILLCHDLNWELPVLQAAREAKPFYLGALGSYRTHTLRLQKLHELGWSREETTQ
                     IRAPVGIFPKARDAHTLALSVLAEVASVRLHQEEDSCLPPSS"
     gene            6005..6343
                     /locus_tag="RH288_004326"
                     /pseudo
     CDS             6005..6343
                     /locus_tag="RH288_004326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308332.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
BASE COUNT         1656 a         1915 c         1877 g         1503 t
ORIGIN      
        1 tacatcatcc tgaagtagcg cgatatactc actgactatc tgcatcagaa tataaaaagc
       61 aatgttttta acctataaaa atggcgctgt atttgcgcca tttttatcat tcaatgcatt
      121 atctgtttga gcctaaaggg atctcagggt ctggctcatg agtaattctg tttcgtaaat
      181 ctctgcgaat aatttcaata gaccagaacc agactaaatg tccaaaaatt tcagaaacat
      241 tctcatacca cgggagatca aacagaggtg gcgtcagtcc catgagaggg aatgaaatca
      301 tatgaacaaa aagttgggct aaagcacctg ccagtaagcc ctgccagagt ttaatttttg
      361 gaaatacttc agcgaccaca caataaccga cagcaaacac tatcgaaaag ataatgtgcg
      421 taacaccaac ccagttaaag acatgcccgg caaaggtata aacagccgca ttgggatctg
      481 tcagccccaa ccagtctcga agaaaaatat acggtggatt gagaaaatta cgcgagcaat
      541 caatttggcc tgcagccctg attaatgatt ccgggccaca cgctgcatta aacatatcca
      601 ccgggctacg tggcggcaat ggaacttcag ccccccactt cacgaatgcg gaaacaacgc
      661 cagcaatcag cccaatgaat gcagcaagac cataacgtct gcggttcggt agagtttgtt
      721 caaatatatt catatctacc ctgcttgtac cattatgtta tacacctctt caggagtatt
      781 cataaaacaa ggcaaatgta aagaactgta ttgttttgta taacaagata gtttcctaat
      841 cgccaatgaa tataagctcc atcatttctc cctattttta tattagaagt gacagagatt
      901 tgcagggtga tgtagagctg aaaatcacag gtttccttat tggtttttgc atcgtacaac
      961 taaagcaata aaccagctcc catcatcatc aacatcccgg cgaacatgaa tttattagcc
     1021 gggctcatag ctgcattcgc gttttaagaa taatcctcct gctgtcgccg actatgctta
     1081 acgtttaaaa aagcatcagc actctcgcaa cgcactctta ttttcccctt tagaataccg
     1141 gaggcctggt atgagcaacc aaggcgaata ccccgaagat aatcgggttg ggaagcacga
     1201 gccgcacgat ttaagtttga cccgtcgcga tctgattaaa gtgagcgccg caacagcggc
     1261 gaccgccgtg gtttatcctc attctacgct ggcggcaagc gttccggcag ctacacccgc
     1321 gccagagata atgcccctga cactgaaggt gaacggcaaa accgagcagc ttgaggtgga
     1381 tacccgaacc acgctactgg acactttgcg tgaaaatctg catttgatcg gtaccaagaa
     1441 aggttgcgat cacggacagt gcggagcctg taccgtgctg gtcaatggtc gcaggcttaa
     1501 tgcctgcctg acgcttgcag tcatgcatca gggggccgag atcaccacca ttgaaggcct
     1561 gggttcgcca gataatcttc accccatgca ggcggccttt atcaagcatg atggcttcca
     1621 gtgcggctac tgcacctccg ggcaaatttg ctcatcagta gcggtgctaa aagagattca
     1681 ggacggcatt cccagtcacg tcacggtcga tttggtttcc gctccagaaa caactgccga
     1741 tgagatccgt gaacgtatga gcggcaacat ctgtcgctgt ggtgcatacg ctaacatcct
     1801 tgccgccatt gaagatgctg cgggggagat aaaatcatga aggcgtttac ctatgaacga
     1861 gtgaataccc cagccgaggc ggcacttagc gctcagcgcg tacccggcgc aaaatttatc
     1921 gcgggcggga ccaatctgct ggacctgatg aagctggaaa ttgaaacgcc cacccacctt
     1981 atcgatgtga acggcctcgg gctcgataag attgaagtga ccgacgcggg tgggctgcgc
     2041 atcggcgcac tggtacggaa caccgacctg gcggctcacg agcgcgtgcg tcgtgattac
     2101 gcggtactct cccgcgccct gctcgctggc gcgtctggtc agttacgtaa tcaggcaacc
     2161 accgcaggta atctgctcca gcgcacgcgc tgcccctatt tttacgacac caatcagccc
     2221 tgcaataagc gcctgcccgg gagcggctgc gcggcgcttg aaggctttag ccgtcagcac
     2281 gcggtggtag gcgtaagcga agcctgcatt gccacccatc cgagcgatat ggcggtcgca
     2341 atgcggttgc tggatgcggt ggtggaaacc atcacgccgg agggaaagac tcgcagtatc
     2401 acactggctg atttttatca ccctccggga aaaacgccgc acattgaaac cgccctgctt
     2461 cccggtgagc ttatcgttgc ggtgacgtta cctccaccgc tcggcggaaa acatatctac
     2521 cgtaaggtgc gcgatcgcgc ctcctacgcc tttgccctgg tatcggtcgc ggcgattatt
     2581 cagcctgacg gcagcgggcg cgtcgcgctg ggcggagtag cacataagcc ctggcgcatt
     2641 gaggctgcgg atgctcagct atcccagggg gcgcaggccg tatatgacac gctgttcgcc
     2701 agcgcccatc ccaccgctga aaacaccttt aaactcctgt tggcgaagcg aacgcttgcc
     2761 tccgtactgg ctgaagcgag ggcacaggca tgaaatttga taaacccgca ggggaaaacc
     2821 cgatcgatca gctgaaggtt gtcggtcgtc cccatgaccg catcgacgga ccgctgaaaa
     2881 ctaccggcac ggcacgctac gcctacgaat ggcatgaaga agcccccaac gccgcctatg
     2941 gctatatcgt cggttccgcc attgccaaag gacgcctcac cgcccttgat acggacgccg
     3001 cgcaaaaagc gccgggcgta ctggctgtca ttaccgccag taacgccggg gcactcggca
     3061 aaggcgacaa aaacaccgcc aggctgttag gcggccccac tattgagcac tatcatcagg
     3121 ccattgcgct ggtagtggcc gagaccttcg aacaggcgcg agcggcggcc tcgctggtgc
     3181 aggcacacta tcgccgtaat aaaggagctt actccctggc ggacgaaaaa caggccgtca
     3241 atcagccgcc ggaagacacg cccgacaaaa acgtcggtga ctttgacggg gctttcacct
     3301 ccgctgcggt gaagattgat gctacctaca cgaccccgga ccagagccat atggcgatgg
     3361 agccgcatgc ctcgatggcc gtctgggatg gaaataagct taccctctgg acctcaaatc
     3421 agatgattga ctggtgccgc accgatctgg caaaaacgct gaaagttccc gtggagaatg
     3481 tgcgtattat ctccccgtat atcggcggag ggtttggcgg caagctgttc ctgagaagcg
     3541 atgcgctgct ggcggccctc gccgcccgag cggtgaaacg tccggttaaa gtgatgctcc
     3601 cccgcccctc tattcccaat aacaccacgc accgccccgc cacccttcag cacttgcgta
     3661 tcggtgccga ccagagcggg aaaatcaccg ctatctcaca tgaaagctgg tctggaaacc
     3721 tgcccggcgg cacgccggaa acggcggtac agcaaagcga attactctac gccggggcga
     3781 atcgtcatac cggcctgcgg ctcgccacgc ttgatttgcc ggaagggaac gccatgcgtg
     3841 cgcccggcga agcccccggt ctgatggcgc tcgaaatcgc gatcgacgaa ctggcggaaa
     3901 aagcgggcat cgatcccgtc gagtttcgca tcctgaatga cactcaggtt gaccccgccg
     3961 acccgacgcg ctgcttctct cgccgtcagc ttatcgagtg cttgcgcacc ggagcggata
     4021 aatttggctg gaagcagcgc aacgccacac ccggacaggt gcgcgacggg gagtggctag
     4081 tcggccacgg tgttgcggcg ggctttcgca ataatctgct ggaaaaatcg ggtgctcggg
     4141 ttcacctcga acaaaacggc accgttaccg tagaaacgga catgaccgac attggcaccg
     4201 gcagctacac cattctggcc cagacggcag cggaaatgct tggcgtaccg ctggagcagg
     4261 ttgcggttca cctcggcgat tccagtttcc cggtttctgc gggttctggt ggacaatggg
     4321 gcgcgaatac ctccacctcc ggcgtttacg ccgcctgtat gaagcttcgc gaaatgattg
     4381 cctcggcagt cgggtttgat cctgagcagt cgcagtttgc cgacggcaag attaccaacg
     4441 gtacccgaag cgccacgcta catgaagcca ccgcaggcgg cagactgaca gcggaagaga
     4501 gcattgaatt cggaacactg agcaaagagt accagcagtc gacctttgcc gggcattttg
     4561 tggaggtcgg cgtgcatagc gcgacgggag aagttcgggt ccggcgtatg ctcgctgtgt
     4621 gtgctgcagg acgcatcctg aatccgaaaa ctgcgcgcag ccaggtcatt ggcgcaatga
     4681 ctatgggcat gggcgcggca ctgatggagg agctggcggt ggatgaccgt ttgggctact
     4741 tcgttaatca cgatatggcg gggtatgagg tgccggttca tgcggatatc ccaaaacagg
     4801 aggtgatttt cctggatgat accgacccca tatcctcccc gatgaaggcc aaaggtgtcg
     4861 gtgagctggg cctgtgcggc gtgagcgcgg ctatcgccaa cgcggtgtat aacgccaccg
     4921 gtattcgggt acgggattat cccatcactc tggataagct gctcgataag ctgccggatg
     4981 tggtttaagg aggaacaatg tcatacccgc tttttgacaa agacgaacac tggcataagc
     5041 cagagcaggc gtttctcacc gatgaccacc ggaccattct gcgcttcgcc gtagaggcgc
     5101 taatgtccgg taaaggagcg gtgctggtga cgctggtgga gatacgcggc ggcgcggcgc
     5161 gcccgctcgg ggcgcagatg gtggtgcgcg aagatggtcg ttactgcggt tttgtctctg
     5221 gcggctgcgt ggaggccgct gccgcttttg aagcgctgga gatgatgggc tcaggccgcg
     5281 atcgcgaaat tcgctatggc gaaggttcgc cgtggtttga catcgttctg ccctgcggcg
     5341 gtgggatcac gctgacgctc cataaactac gctcggcaca gcctctgctc gccgtgctga
     5401 accgcctgga acagagaaaa ccggtggggc tgcgctacga tccgcaagca caatcgctgg
     5461 tgtgcctgcc cacgcaaacc cggacgggct ggaatctcaa tggctttgag gtggggttca
     5521 ggccatgcgt caggctgatg atttacggac gttctcttga ggcgcaggca accgcgagtc
     5581 ttgcagcagc cacaggctat gacagccata tcttcgatct ttttccggcc tcagccagcg
     5641 ctcagatcga taccgatacg gcggtcattt tgctgtgcca tgatctcaac tgggagctgc
     5701 cagtgttgca ggccgcgcga gaagcaaaac ccttttatct cggcgcattg ggcagctatc
     5761 gaacccacac gttacgtctg caaaagctcc acgagctggg atggtccagg gaggaaacaa
     5821 cgcaaatccg ggcacccgtc gggatattcc ccaaagcccg ggatgcgcat actctggcac
     5881 tctccgtgct ggcagaagtc gcctctgtac gtctccatca ggaggaggat tcatgcctgc
     5941 ccccgtcgtc ctgatccttg cggccgggcg tggagagcgc tttctcgcct ccgggggaaa
     6001 tacccataag tgtatcggct ggcgtcagtc cccggaggtt gcgccttatc gctggccatt
     6061 tgaagaaaac gggagaactt tcgaccttgc gattgaaccg cagattacga ctaatgatct
     6121 gcgtctgatg ttgaggctgg ctcttgccgg cggaggaata acaattgcca ctcaggaaac
     6181 tttcaggcca tatattgaaa gcggtaagct tgtatcgctg cttgatgact ttcttccaca
     6241 atttccgggc ttctatctgt atttcccaca gcgtcgcaat attgcaccaa agctccgcgc
     6301 cctgattgac tacgtcaaag aatggcggca gcaattggct taaatgtctg cacctgcact
     6361 gcctgatgtc agaacagtat tttgatgaat tgccaaggtt acaatggcac aaatacggca
     6421 caggaggaaa cgtggtgtat ttaaatatgg ggtaactctt tgattttaat ggtgcgataa
     6481 taggagtcga acctacgacc ttcgcattac gaattataag aatccgcttc taattcaaat
     6541 cattacccca tcaacactgc gctcacacgt cccaccaaat caaaacatgt aaagccttgc
     6601 aagccattgc gaggccttat gtgtctcagt tttgtcccac cttgtattac gacttgcata
     6661 gccaatgaag ataaacgtga cgacaaacgg cgcagcggtc ttcttttcct ttatactttc
     6721 cccacccagc atgcatacct tctaccataa ctgtagtgaa tgtctgttat gggcgaagag
     6781 cggaaaaagc atactgagat cgcccggaat atgtcccata cttttgatga gctaattgtg
     6841 tacctcaagg tggatgtcga ggcttaacct cgtagttatc atctgcgcgt accttttcaa
     6901 acagtttgtt atcgctagca aataacatct aaggcttcag ggccaataga t
//
LOCUS       DAPHKZ010000191         6929 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.192, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000191 DAPHKZ010000000
VERSION     DAPHKZ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6929
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.192"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            457..984
                     /locus_tag="RH288_004327"
     CDS             457..984
                     /locus_tag="RH288_004327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDV4033306.1"
                     /translation="MSARGINKVILVGRLGNDPEVRYIPNGGAVANLQVATSESWRDK
                     QTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEIL
                     VKTTGTMQMLGSAPQQNAQAQPKPQQNGQPQSADATKKGGVKTKGRGRKAAQPEPQPQ
                     PPEGEDYGFSDDIPF"
     gene            1042..1275
                     /locus_tag="RH288_004328"
     CDS             1042..1275
                     /locus_tag="RH288_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDV4033307.1"
                     /translation="MSEYFRILQGLPDGSFTREQAEAVAAQYRNVFIEDDHGEHFRLV
                     VRNNGALVWRTWNFEDGAGYWMNHAIRDFGILK"
     gene            1334..3292
                     /locus_tag="RH288_004329"
     CDS             1334..3292
                     /locus_tag="RH288_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDV4033308.1"
                     /translation="MPVTKCEPETTRKASRKSAKTQETVLSALLAQTEEVSVPLASLI
                     KSPLNVRTVPYSAESVSELAESIKGVGLLQNLVVHALPGDRYGVAAGGRRLAALNMLA
                     ERNILPADWPVRVKIIPQELATAASMTENGHRRDMHPAEQIAGFRAMAQEGKTPAQTG
                     DLLGYSPRHVQRMLKLADLAPVILDALAEDRITTEHCQALALENDTARQVQVFEAACQ
                     SGWGGKPDVRVIRNLITESEVAVAGNSKFRFVGADAFSPDELRTDLFSDDEGGYVDCV
                     ALDAALLEKLQAVAEHLREAEGWEWCAGRMEPVGECREDAGTYRCLPEPEAVLTEAEE
                     ERLNELMTRYDALENQCEESDLLEAEMKLMRCMAKVRAWTPEMRTGSGVVVSWRYGNV
                     CVQRGVQLRSEDDAADDADRTEQVQEKASVEEISLPLLTKMSSERTLAVQAALMQQPD
                     KSLALLAWTLCLNVFGSGAYSKPAQISLECKHYSLTSDAPSGKEGAAFMALMAEKARL
                     AALLPEGWSRDMTTFLSLSQEVLLSLLSFCTACSIHGVQTRECGHTSRSPLDTLESAI
                     GFHMRDWWQPTKANFFGHLKKPQIIAALNEAGLSGAARDAEKMKKGDAAEHAEHHMKD
                     NRWVPGWMCAPHPQTDATERTDNLADAA"
     gene            3347..3781
                     /gene="psiB"
                     /locus_tag="RH288_004330"
     CDS             3347..3781
                     /gene="psiB"
                     /locus_tag="RH288_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HDV4033309.1"
                     /translation="MKTELTLNALQSMNAQEYEDIRAAGSDMRRNLTHEVMREVDAPA
                     NWMMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQLWMLVLVNCGGQPFAVV
                     QVQHIFTPVAISHTLALAATLDAQGYSVNDIIHILMAEGGQA"
     gene            3778..4497
                     /locus_tag="RH288_004331"
     CDS             3778..4497
                     /locus_tag="RH288_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001723065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HDV4033310.1"
                     /translation="MSARSRALIPLSAEQQAAMQAVAVTEQRRRQGRTLSAWPYASAF
                     FRCLNGSRRISLTDLRFFAPALTKEEFHGNRLLWLAAVDKLIESFGEVCVLPLPSDAG
                     HRLFPSVPFREGERRRQKTTLTEQKYSRQREREAERRELEYQTCFAQAQIDLAFHTPA
                     TVGSWLSRWSGVVEEHDLETIFWGWCGRFPSLSSFDRFFWQEEPLWRLIFEAGEAGRG
                     APVQIRALEQWMIPNKLENAI"
     gene            4627..5802
                     /locus_tag="RH288_004332"
     CDS             4627..5802
                     /locus_tag="RH288_004332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV4033311.1"
                     /translation="MLRATKIRIYPTPEQAAFLNAQFGAVRFAYNKALHIKKHAYQRH
                     GVNLSPRNDLKPLLSVAKKSRKYAWLKEFDSMALQQAVINIDVAFSNFFNPKLKARFP
                     TFKRKHGKQSSYHCVGIKVLDNAIKIPKLAPIEARLHRELHGKLKSITVTRSATGKYY
                     ASILCDDGASAPEKPTYLKEEKITGLDMGLEHYAITSDAVKVPNPRHLINVSRNLRRK
                     QKALSRKQKGSANRKKARIRLAALHERVANARADFQHKLSRAIVDENQAVIVETLKTA
                     NMMKNHNLARAIGDAGWHSFITKLEYKAATKGVHLVKLDQWFASSKTCHCCGYKMPEM
                     PLHKRIWRCPECGAEHDRDINAALNIRQKGILELKAAGLVVSAHGGQRKSVAQTVAA"
     gene            6249..6749
                     /locus_tag="RH288_004333"
     CDS             6249..6749
                     /locus_tag="RH288_004333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDV4033312.1"
                     /translation="MSVVAPAVYVGTWHKYNCGSIAGRWFDLTTFDDERDFFAACRAL
                     HQDEADPELMFQDYEGFPGNMASECHINWAWVEGFRLARDEGCEEAYRLWVEDTGETD
                     FDTFRDAWWGEADSEEAFAVEFASDTGLLADVPETVALYFDYEAYARDLFLDSFTFID
                     GHVFRR"
BASE COUNT         1547 a         1871 c         2082 g         1429 t
ORIGIN      
        1 cgctacggtc cgatgcgtga aaacccgggc ttgcagcgac cgttccggtc gcgccgcccc
       61 tgtcgcgccg tgacctgcgc tccctgcaca cctgacggtg tgtgaggaaa ctgcgcctga
      121 tggcgcagca gtcttccctc ctgccgccac ctctgcggcc tgtttcccgc tgtggacttt
      181 ccggggggca gacgtaaccc cctcccgttc catctgtcca gggtgagatg caccggccac
      241 aaaattttta gccatgaacc cggcaaaaaa ttttgcgtcc gcccccggac agctgtcccg
      301 tgaggcggta aacgggcccc catcggaaag gtccactgcg gggagaaacc cctgtgaagt
      361 ggacggcagg aggagctttc gctcctctga aggggcacat gaacgtcccg tcgccggtat
      421 ccggtttatc tcacatcttt cagtcaggag gttcttatga gtgcacgtgg tatcaacaag
      481 gtcatcctcg tcgggcgtct gggcaatgat ccggaagtcc gttacatccc caacgggggc
      541 gcagtggcaa acctgcaggt ggctacgtca gaaagctggc gcgacaaaca gacgggggag
      601 atgcgggagc agacggaatg gcaccgcgtg gtgctgttcg gcaagctcgc ggaagtggct
      661 ggtgaatatc tgcgcaaggg cgcgcaggtc tacatcgagg ggcaactccg tacccgtagc
      721 tgggaagata acggtatcac ccgttacgtc actgaaattc ttgttaagac cacgggcacc
      781 atgcagatgc tggggagtgc accacagcag aacgctcagg cgcaaccgaa gcctcagcag
      841 aatgggcagc cacagagtgc tgacgcgacg aaaaaaggtg gcgtgaaaac gaaaggccgt
      901 ggacgtaagg ccgcgcagcc cgagcctcag ccgcaaccgc cggaggggga ggattacggg
      961 ttttcagacg atatcccgtt ctgactggcc tgactgtgat aaccgccccg ccctgcgcgg
     1021 ggcatcaccg gagatatgag gatgagcgaa tatttcagaa tacttcaggg gctgcctgac
     1081 ggctccttta cccgcgaaca ggcggaagcc gttgccgcac agtaccggaa cgtctttatc
     1141 gaggatgacc acggggaaca ttttcgcctg gttgtccgca ataacggtgc cctggtctgg
     1201 cgtacctgga attttgagga cggtgccggg tactggatga atcatgccat cagggatttc
     1261 gggattctta agtaagagag gtgccggacg cgcgaacgtc cggcaggaca taagcaatta
     1321 taaggggatg attatgcctg taacgaagtg tgaaccagaa accacccgca aagcaagccg
     1381 taaatctgca aaaacgcagg aaacagtcct gtctgccctg ctggcgcaga cggaggaagt
     1441 gagcgtgccg ctggcctcac tgattaagtc accgctgaat gtgcgcacgg tgccgtattc
     1501 tgcggagtcc gtcagcgaac tggctgagtc cattaagggc gttggcctgc tgcagaatct
     1561 ggtcgtgcat gccctgccag gtgaccgtta cggtgtcgcc gcaggcggtc gccgactggc
     1621 agcactcaac atgctggcag agcgcaacat ccttccggct gactggcctg tccgcgtgaa
     1681 aattattccg caggaactgg cgacggctgc atcgatgacc gagaacggtc atcgtcggga
     1741 tatgcaccca gccgaacaga ttgccggatt ccgcgcaatg gcgcaggaag gcaaaacacc
     1801 tgcgcagact ggcgacctgc tgggctattc accccgccac gtccagcgaa tgctgaaact
     1861 ggcagacctt gcacccgtca tccttgatgc gctggcagaa gaccgcatca ccaccgaaca
     1921 ctgtcaggcg ctggcgctgg agaacgacac cgcgcgtcag gtgcaggtgt ttgaagccgc
     1981 ctgccagtca ggatggggcg gtaaaccgga tgtgcgggtt atccgcaacc tgattaccga
     2041 aagtgaagtg gcggtggcgg ggaacagtaa attccgcttc gtgggggctg atgccttctc
     2101 gccagacgaa ctgcgcaccg atttgttcag cgacgacgag ggtggctatg tggactgcgt
     2161 ggcgctcgat gccgccctgc tggaaaaact ccaggctgtc gctgaacacc ttcgggaagc
     2221 cgaaggctgg gaatggtgcg ccgggcgcat ggagcctgtc ggtgagtgcc gtgaggatgc
     2281 cggaacatac cgctgtctgc cggagccgga agcggtgctg acggaggcag aagaagaacg
     2341 cctgaacgaa ctgatgacgc gttacgacgc gctggaaaac cagtgtgagg aatccgacct
     2401 gctggaagca gaaatgaagc tgatgcgctg catggcgaag gtcagagcgt ggacgccgga
     2461 gatgcgtacc ggaagcggtg tggtggtgtc ctggcgttac ggtaatgtgt gtgtccagcg
     2521 tggtgtgcag ttgcgcagtg aagatgacgc ggctgacgac gctgaccgca cggaacaggt
     2581 gcaggaaaaa gcgtcagtgg aggaaatcag tctgccactg ctgacgaaaa tgtcttccga
     2641 acgcacgctg gcagtccagg cggcactcat gcagcaaccg gacaaatctc tggcactgct
     2701 ggcatggacg ctctgcctga atgtgtttgg cagcggagcg tacagtaaac cagcacaaat
     2761 cagcctggaa tgtaaacatt attcgctgac cagcgatgcg ccgtcaggga aggaaggtgc
     2821 cgcgttcatg gcgctgatgg cagaaaaagc ccgtcttgcg gccctgttac cggagggatg
     2881 gtcacgggac atgacgacgt tcctgtcgct cagccaggag gtgctgttat ccctgctcag
     2941 tttctgcacc gcgtgcagca tccacggcgt tcagacccgc gagtgtggtc acacgtcacg
     3001 cagcccgctg gatacgctgg agagcgccat cggttttcac atgcgcgact ggtggcagcc
     3061 gacaaaagca aacttcttcg gacacctgaa aaagccacaa attatcgcag ccctgaatga
     3121 ggccggactg tccggtgccg cacgggacgc ggagaagatg aagaaaggtg atgcggctga
     3181 acatgcagag caccatatga aagacaaccg ctgggttcca ggctggatgt gtgctccaca
     3241 tccacagaca gatgccactg aacgcaccga taacctggct gatgccgcct gatgaacaac
     3301 cacaccgccc cgccggagac ggggcggcag caagggagat accgtgatga aaactgaact
     3361 gaccctgaat gccctgcagt ccatgaacgc acaggaatat gaagatatcc gtgctgcggg
     3421 aagcgatatg cgccgtaatc tcactcacga ggtgatgcgt gaagtggacg caccggctaa
     3481 ctggatgatg aatggcgagt atggcagtga gttcgggggc tttttccccg tccaggttcg
     3541 tttcacgcca gcccacgaac gtttccacct ggcattatgt tcgccgggag acgtctctca
     3601 gctctggatg ctggttctgg tgaattgtgg tggacagcct ttcgccgtcg ttcaggtgca
     3661 acatatcttc acgcctgtcg ctatcagtca cacgctggcg cttgccgcga cacttgatgc
     3721 gcaggggtac agtgttaacg acatcatcca tatcctgatg gcagaaggag gtcaggcatg
     3781 agcgcacgtt cacgggcact gatccccctc agcgcagagc aacaggccgc catgcaggct
     3841 gtggctgtca cagaacaacg tcgtcgtcag ggacgcacac tttcagcatg gccttatgcc
     3901 agcgctttct ttcgctgcct gaatggcagc cgccggattt cgctgaccga tctccgcttt
     3961 tttgctcctg cgctgacgaa ggaggaattt catggcaacc gtctcctgtg gctggctgcc
     4021 gtggataaac tgattgaaag ttttggtgaa gtctgtgttc ttcccctgcc atccgatgct
     4081 gggcatcgtc tgttcccgtc cgttcctttt cgtgaaggtg agcggcgtcg tcagaaaacc
     4141 acgctgacag agcagaaata cagccgccag cgggaacgtg aggcagaacg acgggaactg
     4201 gaataccaga catgttttgc tcaggcgcag attgaccttg cgtttcatac tcccgccacg
     4261 gtcggaagct ggttgtcccg ctggtctggt gttgttgagg agcatgatct ggaaacgatt
     4321 ttctgggggt ggtgcgggcg ttttccatca ctgtcatcat ttgaccggtt tttctggcag
     4381 gaggaaccac tctggcggct gatttttgaa gccggtgagg ccggtcgtgg tgcaccggta
     4441 cagatacgtg cacttgagca gtggatgatc ccgaacaagc tggagaacgc aatatgatga
     4501 aatcagcgaa aagccgccga gaaccctcgc ccaatgcggg tggggaggaa aggcggaaaa
     4561 gcccgaaggg ctttaaaaat attattacgg tgttagcata aaaacctgta ccaatgagcg
     4621 gtgactatgt taagagcaac aaaaatacgc atctatccta ctcctgaaca ggctgcattt
     4681 ctcaacgccc agttcggtgc ggtacgtttt gcgtacaaca aagctcttca catcaaaaaa
     4741 cacgcttacc agagacacgg agtaaattta agtccgcgta acgatctgaa accgttgttg
     4801 tctgtggcca aaaagtcccg taaatatgcc tggctcaaag aatttgactc aatggcattg
     4861 caacaggcgg taatcaatat tgatgtggca ttttccaact tttttaatcc gaagctgaaa
     4921 gcgcggttcc cgacgtttaa acgcaaacac ggaaaacaat cgagctatca ctgtgtcggg
     4981 attaaggtgc tggataatgc catcaaaatc cccaaactgg ccccgataga agcacgcctt
     5041 catcgtgaac ttcatggaaa gctgaaaagc atcactgtca cccgttctgc aacggggaaa
     5101 tactacgctt ccattctttg tgacgatggc gcttccgcac cagagaaacc cacgtacctg
     5161 aaggaagaaa agattacagg tctggatatg ggactggagc actatgccat cacttctgat
     5221 gctgtaaaag ttccgaatcc tcgccatctt atcaatgtaa gtcgtaatct gcgacgcaaa
     5281 caaaaagcat tatcccgtaa gcaaaaggga agcgcgaatc gtaaaaaggc cagaatccgt
     5341 cttgcggcct tacacgaacg ggtggcgaat gcccgtgctg attttcaaca caagctctct
     5401 cgcgcgattg tcgacgaaaa ccaagcggta attgtggaga cgctgaaaac agccaacatg
     5461 atgaaaaacc acaatctggc aagagcgata ggtgatgctg gctggcacag cttcatcaca
     5521 aagctggagt acaaggcagc gacaaaaggc gttcacctgg taaaactcga ccagtggttt
     5581 gccagttcga aaacgtgcca ttgttgtggt tacaaaatgc cggaaatgcc acttcataaa
     5641 cgcatctggc gatgccctga gtgtggagca gagcacgacc gcgatatcaa tgcggcactc
     5701 aacatccggc aaaaaggaat actggaacta aaggcggcgg gactcgtcgt ctctgcccat
     5761 ggaggccagc gtaaatccgt cgcacagacg gttgcggcct gagaagtggg aagcctcgcc
     5821 cgacagggcg gggagcagtc acgggtggtc tggaggtcat gcggcgtgtc ctctgcactc
     5881 gccggaataa ggaagtcgcc ggcggctccg cttttacccg gccatgcggg gcatggcctt
     5941 gtggggtttc agctctgtgg cctcagcgtc gtgtgcgggc tgtgccgtgc ctccatctta
     6001 gccgggctgg cagggatgca agggtacgct tcgccgctgc ggtcacccgg tccctccttc
     6061 ccgtctgccg tgattttccg gtcgttcgtc cgctcaggtt tcgcggcctc accctgcaac
     6121 tcccgtcagc cgtgtgcgtc aggctgcggc ttcccttgcg cccctgcatc cccgccttat
     6181 cgcccggctt ttatggaggc acggcaccgc ccggtgtcgc agaacatgtg actatggagg
     6241 attcgggaat gtctgttgtt gcacctgctg tatacgttgg aacctggcac aaatacaact
     6301 gtggaagcat cgccggacgc tggtttgacc tgaccacgtt tgatgatgag cgcgactttt
     6361 tcgccgcctg ccgtgctctt caccaggatg aagccgatcc tgaactgatg tttcaggatt
     6421 atgagggatt cccggggaat atggcctctg aatgccatat caactgggcc tgggttgaag
     6481 gcttccgcct ggcacgggat gaaggctgcg aagaggctta tcgtctctgg gtggaggata
     6541 ccggtgagac ggattttgac accttccgcg atgcctggtg gggcgaggct gacagtgagg
     6601 aggcttttgc ggttgagttc gccagtgata ccggcctgct ggctgacgtg ccggagacgg
     6661 tggcgctcta ttttgactat gaggcgtatg cgcgggattt attcctggac tccttcacct
     6721 ttattgacgg tcatgtgttc cgtcggtgat ttactccccc gctccggcgg gggtatggcc
     6781 tgccaggccg ccggaaaacc ctggcaggct tacgcctgcc tgaaatgcag gagggccgcg
     6841 cctgcggcgc tgcccttcct gcccgtcatg gtgtgaggca tttttctgtt atgtcgtttc
     6901 tgttgttctg atttccggag gcggggaca
//
LOCUS       DAPHKZ010000192         6769 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.193, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000192 DAPHKZ010000000
VERSION     DAPHKZ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6769
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.193"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(189..497)
                     /locus_tag="RH288_004334"
     CDS             complement(189..497)
                     /locus_tag="RH288_004334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone GroEL"
                     /protein_id="HDV4033313.1"
                     /translation="MSKAKFSAQAEKLKNLVDSARLQTSSSAVTATAPSQPNEGAEEV
                     SGRPVAARTKAKNLKAIPLSYFEAHAELKATSKTSLDFSSYIIEAIREKLERDGAIGQ
                     "
     gene            complement(584..1228)
                     /locus_tag="RH288_004335"
     CDS             complement(584..1228)
                     /locus_tag="RH288_004335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDV4033314.1"
                     /translation="MPVIANTHPKGGVGKTTSSVNIVGEMKSDTVDLDTHTGLSIILG
                     LRPEGKEISVKVPKTVDELIEIMTPYKNSDKTLLIDCGGFDSDLTRTAIAFADCVIVP
                     SKDSLTERIGLMHFDGVLDEISSIMGTDITAHLYLCKVNPNKKKFPKLDAILPSFKHL
                     KLMKSRISARAEFEDVIETGMGITESVHGRYSAGGKEVIALIEEINHLIENNKQ"
     gene            complement(1408..2214)
                     /locus_tag="RH288_004336"
     CDS             complement(1408..2214)
                     /locus_tag="RH288_004336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HDV4033315.1"
                     /translation="MSGSVIHSQSAAMVPAVYSAGQSAQLPVAIDYPAALALRQMSMV
                     HDELPKYLLAPEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPF
                     VQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNKR
                     TGRTEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPITPHTFRHSYAMHMLYAGIP
                     LKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFSMPESDAVSMLKRIP"
     gene            complement(2215..2520)
                     /gene="ccdB"
                     /locus_tag="RH288_004337"
     CDS             complement(2215..2520)
                     /gene="ccdB"
                     /locus_tag="RH288_004337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="HDV4033316.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD
                     KVSRELYPVVHVGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     gene            complement(2522..2740)
                     /gene="ccdA"
                     /locus_tag="RH288_004338"
     CDS             complement(2522..2740)
                     /gene="ccdA"
                     /locus_tag="RH288_004338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="HDV4033317.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTLQNEARRLRAERW
                     QAENQEGMAEVARFIEMNGSFADENRDW"
     gene            3298..4224
                     /locus_tag="RH288_004339"
     CDS             3298..4224
                     /locus_tag="RH288_004339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033318.1"
                     /translation="MSEKEHDMTNDGGESVTYTLRNIPADTDRVITDLASHARKPKAT
                     FLREFLEDSFRDVIDSFALKNPLIASLDEELASYLDAKVMEQRYQSHFITRWNQEYQK
                     LLGISTEEELRRLVLNNTPFLQVRADQVLKGWKNIPRGISLTFSLFAEIAGRDRETID
                     QAWKNIFYSQLREKKHRFYQDIEAIRALKKLPALTGDSWTRDGITVRIYRPENYARGA
                     WRVTLSLPENYATQMWNIPFPELEYRLFTADPGYSALISAEPDRWDKAFRFVDGVCEL
                     HLYTNGVEEDHNPTPLGDVAQALINVVEENLL"
     gene            4269..4523
                     /locus_tag="RH288_004340"
     CDS             4269..4523
                     /locus_tag="RH288_004340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033319.1"
                     /translation="MKGRQSRYVTGGESFAEIARLPSGAVVRLCLNTGLEDALREASK
                     SLKSAFTRSGRKCRLSAGTAQGPFTGRRQGVATHLFVSVL"
     gene            5022..5366
                     /locus_tag="RH288_004341"
     CDS             5022..5366
                     /locus_tag="RH288_004341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HDV4033320.1"
                     /translation="MKNLLDTEGTVLFPFQTEIHFIWTIFSTVKRLVIGTRDHICQKQ
                     YWSACLCILLLMAYVGLCAAVVWFVVPWLKAFIVSKFAVSALWVTPVKRGLLWGIGKV
                     VTATCRRFTLLK"
     gene            complement(5542..6543)
                     /locus_tag="RH288_004342"
     CDS             complement(5542..6543)
                     /locus_tag="RH288_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4238 domain-containing protein"
                     /protein_id="HDV4033321.1"
                     /translation="MADPFNLQTDVVRQHTVPRFLLKHFSTPGKGKRQRLYAFDKAAG
                     RAYATTPDDATVRNTFYNLDNHPDRLSLEPLLGIYEHHAAPVIAALLAHRDIRRLTDD
                     ERYRLAVFVAVQRARTFGELERISGMISVLTDKMEAIGSTKEQAMETLGLSSGGDTKD
                     IFLRQLVQQVSHIDLLLKKDWYLLETRPERPFYVSDNPVVLKNSNDFGPYGNLGLAVS
                     GIQIYLPLSSTLMLAMYCPSIREQMVRQKQHLQHLLARAPHLIPRHIRPFERLEHIRR
                     YTDYLLMPLTPEHVTHYNSLQVEFAEQYVFCGEKDFSLVERMLADSERYRTGPRFTF"
BASE COUNT         1743 a         1744 c         1688 g         1594 t
ORIGIN      
        1 atcgtggaca tcatggttca ggttaaggga aaaggaatga aatggtgaaa ctgagaggaa
       61 aggaaagcgg tgacgaatca tgtcaccata aacagaaaga tgtctaatgg ggactcttta
      121 ggtacgtgaa gaatccccat aacgcattta aaagacacac atcagatacc cttaaggtat
      181 ccgatagttt attgacctat tgcaccatca cgttcaagct tctctcttat agcctcaata
      241 atatatgagc taaaatccag agatgtttta ctggtcgctt taagttccgc atgagcttca
      301 aaatacgaca gcggtatggc cttaagattc ttagccttcg tcctggcagc cacgggacga
      361 cctgaaactt cctctgcacc ttcatttggc tgagacgggg ctgttgctgt tacggcagaa
      421 gaagaagttt gtaatctggc agaatccacc aggtttttca gtttttcagc ctgtgcacta
      481 aatttcgctt tgctcatgag ataacccagg atgtttgtta gatacttaaa agatatccat
      541 taaaagccca aaggatacta tatggatacc caatagacac accttactgt ttgttatttt
      601 caatcagatg attgatttct tcgatcaggg caataacttc cttacctcct gccgaatagc
      661 gcccatgaac agactcagtg attcccatcc cagtctcaat gacatcctca aattctgcac
      721 gagcagaaat gcggctcttc atcagcttca gatgtttgaa cgatggcagg attgcatcaa
      781 gcttagggaa tttcttcttg ttaggattaa ctttacagag atacaggtga gcagttatat
      841 cggtccccat gatagagctg atttcgtcca gtactccatc aaaatgcatc aaaccaatac
      901 gttcagtcag ggagtctttt gaaggaacaa taacgcagtc tgcaaaggca atcgcagtac
      961 gggtaagatc tgagtcaaat cccccacagt caataagtaa cgtcttatcg ctgttcttgt
     1021 agggagtcat aatttcgatt aactcatcca ctgttttggg tactttcacg gaaatttctt
     1081 ttccttcagg tctcagcccc agaatgatag aaagcccggt atgagtatcc agatcaactg
     1141 tatcagactt catttcacca acaatgttta cggatgaagt tgtcttaccc acaccacctt
     1201 tgggatgcgt attagcaata acaggcatag tgtatctcca gaatccacat gtaataccca
     1261 taaagacccc ataagacacc tttcggatat ccaagaggta ctcaatagat gtttttttac
     1321 tctataccgg tcctgcatgt caacagaata tgaaataccg ataatatatc catgagatat
     1381 ccgaaaggga tttaaaaaag tcagagctta tggaattctt ttgagcatag acaccgcatc
     1441 ggactcaggc atcgaaaact gcacccggtg ccgtgcagcc acatccagcg caaatacctt
     1501 cgtgtagacc tccgttgagc tgatggactt atgccccatc aggctctgca ggaccttcag
     1561 cggtataccg gcatacagca tgtgcatcgc ataggaatgg cggaacgtat gtggcgtgat
     1621 cgggacagag aacgtcacac catcagcggc agcggcggca accgcttccc caatccaggt
     1681 cctgaccgtt ctgtccgtca cttcccagat ccgcgctttc tctgtcctgc ctgttcgttt
     1741 attacgccgt tccatgggga ttttcagtgt tgccaccatc gtctgcagct ggctgacgta
     1801 ccaggagtcg gagagcggga ccagccggtg agtctgctga ccggctggca ttcttcctgc
     1861 cgtcctggcg gctttttcgg tccgttgttt cagggtcgca agctgcacaa acggatacgg
     1921 aggcgtgagc gaaaaatccc cccgcgtcag cgctagtgct tcattaatac gcgcgccggt
     1981 gttccacaga gtggccagca gcatcttgcg gcgcagatcc gggacataat gaagcagggc
     2041 actcacctcg ggagccagca gatatttcgg cagttcatca tgaaccatcg acatctggcg
     2101 gagtgccaga gctgccggat aatcaatggc aacaggaagt tgtgcagact gtccggcaga
     2161 atacactgcc ggtaccatgg ctgcagactg gctgtgtata acggagcctg acatttatat
     2221 tccccagaac atcaggttaa tggcattttt gatgtcattt tctcggtggc tgagatcagc
     2281 cacttcctcc ccgataacgg agaccggcac actggccata tcggtggtca tcatgcgcca
     2341 gctttcatcc ccgacatgca ccaccgggta aagctcacgg gagaccttat ctgacaacag
     2401 acgtgcactg gccaggggga tcaccatccg tcgcccgggc gtgtcaataa tgtcactctg
     2461 gacatccaca aacagacgat aacggctctc tcttttatag gtgtaaacct taaactgcat
     2521 ttcaccagtc cctgttctcg tcggcaaaag agccgttcat ttcaataaac cgggcgacct
     2581 cagccatccc ttcctgattt tctgcctgcc agcgttcggc acgcagacga cgggcttcat
     2641 tctgcagggt ggtgcttacc agcccggaga tattgacatc atatgccttg agcaactgat
     2701 agctgtcact gtcgacggtg actgtaatgc gctgcttcat aatgcacctc atcttacata
     2761 ctctctgtac accattaagt atacaccagt attacgctat aacatgcctc cggcaacgga
     2821 atattgttat ccagctatta ttaacaccac catcaataac tgacctgaaa agtaatcatg
     2881 acaataataa cctgcaatgt agtaaccatg ataaattaca ggatgactgt ttttctatga
     2941 tccgattttt atcggattca ggattttccg gaagtgaatc aggatcagtg aataagcgaa
     3001 gcgatctttt ctgccgctga tgactggctc gggaacacgg gaagaaacac aacatacagt
     3061 gtcatgtcag cggagcggga caccacatcc tgtgaaagcg gaccagcggg cggcagcgaa
     3121 ggatccgcgg atccgtaacc tggggttttc ggatctcaga aaaggaagtg aacagaaaac
     3181 agacagcgaa gcatacgaat tataaaaacg tatgcttcgc agtatttaaa gacactcaaa
     3241 accaggatag agtataagta ttgcagcaat gccccctcac atgaaaaggt acgcgggatg
     3301 agtgaaaaag aacatgacat gacaaacgac ggtggagaga gcgtaacgta taccctgcgg
     3361 aacatccccg ctgacaccga ccgggtgatc accgacctgg caagccacgc ccgtaagcca
     3421 aaggcgacgt ttctgcgtga gttcctggaa gacagcttcc gcgacgtcat cgacagcttt
     3481 gccctgaaga acccgctcat cgcctccctg gatgaggagc tggccagtta tctggacgct
     3541 aaggtcatgg agcagcgcta ccagagccat tttatcaccc gctggaatca ggaataccag
     3601 aagctgctgg ggatctcgac ggaagaggag ctccgccggt tggtactgaa caacaccccc
     3661 ttcctgcagg tccgtgccga ccaggtgctt aaggggtgga aaaatatccc gcgcgggatc
     3721 tccctgacct tctccctgtt tgccgagatc gccggccggg acagggaaac catcgaccag
     3781 gcctggaaaa atatcttcta ctcgcaactg agggaaaaaa aacaccgctt ttaccaagat
     3841 atcgaggcca tccgcgccct gaaaaaactg cctgccctca ccggcgacag ctggacgcgg
     3901 gatggcatca cggtgcgtat ctaccgcccg gaaaattacg cccgcggcgc atggcgcgtt
     3961 acactgagcc tcccggaaaa ttacgccacc cagatgtgga acatcccgtt cccggagctt
     4021 gaataccgcc tctttaccgc cgatccgggc tacagcgccc tgatcagcgc cgaacccgac
     4081 aggtgggaca aggccttccg ttttgtggac ggggtgtgtg agcttcacct ttacaccaac
     4141 ggtgtggaag aagatcacaa tcccaccccg ctcggggatg tcgctcaggc gctgatcaac
     4201 gtggtggaag aaaacctgct gtaacggacc cggatctgcg ggcacaactg catcatcagg
     4261 aggatgcaat gaaaggacga cagagccgct atgttaccgg cggagagagt ttcgcggaga
     4321 ttgcccgtct cccttcaggg gcggtggtga ggctctgtct gaacaccggt cttgaggatg
     4381 cgctgcggga ggcctccaaa tcgctcaagt cagccttcac ccgttccggg cgaaaatgcc
     4441 ggctgtcagc gggtacggcg caggggccgt ttaccggacg ccggcagggc gtggccacac
     4501 atctcttcgt ctcggtactc tgagggggca gggggcaaaa aaagtaaaaa tgtattcgcc
     4561 aggttgcccg gaggtgaagg aaaatagaca tacagcagaa cgacggatag cactttttgc
     4621 taaatggaca tcagtattac tatgctatag ttgctttaat ggataagtgc gccttgacaa
     4681 aggcggtgat ttctgttaac attactctca tagtattgtt ccgtcccgct ccaccccaac
     4741 aagatccgtt tatttcccgc cagactggtt atcaccattc aggcccggat ttttttggat
     4801 ttttttccgg ggagcccccg gaacgagctt aaaatcggta tgacaaacag gaggatgcga
     4861 atgaacacat cataacagag ctgaaagata aaacattctg tacggcatta acagcgttca
     4921 cgtgtgtgag gcgccgggtg ccttttgact taaaaacgag gttattgaga tgaccaaaat
     4981 caagacagtt acttttgtaa atacttaccc gggagggttc tatgaaaaac ttgttagaca
     5041 ccgagggaac ggttctattc ccattccaga ctgaaatcca ttttatttgg acgattttct
     5101 ccaccgttaa acgcctggtt atcggaacca gggaccatat ttgccagaag caatactgga
     5161 gcgcctgtct ctgtattttg cttcttatgg cctatgtggg tctctgtgct gcggtggtct
     5221 ggtttgtagt gccctggctg aaggccttta tagtgtcgaa atttgcggtt tcggcactat
     5281 gggtcacgcc agtaaagcgc ggactactct ggggtatcgg taaagtggtt accgccactt
     5341 gccgaagatt tactctgcta aagtaagtag ccgcaacgct acacgaactg atggtgaatg
     5401 tcaacagata ctcaccatct ccttacggcg gtggtccctg tgaccactgc cgctttcgcg
     5461 tgggtgcaac acggcaaaac tcctctgtac aacaggggct cccgccgtca ttttccggca
     5521 caggtgaggc cggaattcgg actaaaacgt aaaccgcggg ccagtccggt agcgttcact
     5581 atcggccagc attctctcaa ccagagagaa atccttttca ccgcagaaca cgtactgctc
     5641 cgcgaactcc acctgcaggg aattgtaatg cgtgacatgc tccggggtaa gcggcataag
     5701 aagatagtcc gtatacctcc ggatatgttc cagtctttca aaaggccgaa tgtgacgggg
     5761 gataagatgc ggcgccctgg cgagcagatg ttgaagatgc tgcttttgac gaaccatctg
     5821 ttcacggatg gaggggcaat acatggccag catcagcgtc gatgacaggg ggaggtaaat
     5881 ctgtatcccg ctaacggcca gaccaagatt accgtacgga ccgaagtcat tgctgttctt
     5941 aagcactacg ggattgtctg atacgtaaaa cggacgttct ggcctggttt ccagaaggta
     6001 ccagtccttt ttcagcagga gatcaatatg tgacacctgc tggacgagct gccgcagaaa
     6061 aatatccttg gtatcgcccc cggacgacag gcccagggtt tccatggcct gctctttagt
     6121 cgagccgatg gcctccatct tatcggtaag caccgaaatc atgcctgaga tacgctccag
     6181 ttcaccgaag gttcgtgcgc gctgcacggc aacaaacacg gccagcctgt agcgttcatc
     6241 atctgtcagc ctgcgaatat ccctgtgcgc cagcagggct gcaattaccg gtgccgcgtg
     6301 gtgctcgtaa atccccagca gtggttcaag actcagacgg tccgggtgat tatcgaggtt
     6361 gtagaacgtg ttgcggacgg tcgcgtcatc cggcgtggtg gcataggcgc gcccggcagc
     6421 cttgtcaaag gcgtataagc gctgccgctt accctttccc ggcgtactga aatgcttcag
     6481 taaaaaacgg ggaaccgtat gctgcctgac cacatcggtc tgcagattga atggatcggc
     6541 cataacttta tctccctgaa aagccacgca agcgcatcgg tgcatctgta ttgacggcat
     6601 gggcagctgg tttgcagctt agcattagaa aacagaaccg ttcgataata cctgtgttta
     6661 acgccctgtc agtaccgatg gaatttaaat ctccggaatc gccggaaacc ggatctgcac
     6721 gacgggaaac gggcaactga tatgataatt tagcaataca cataaaatc
//
LOCUS       DAPHKZ010000193         6605 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.194, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000193 DAPHKZ010000000
VERSION     DAPHKZ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6605
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.194"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            300..902
                     /locus_tag="RH288_004343"
     CDS             300..902
                     /locus_tag="RH288_004343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proQ/FINO family protein"
                     /protein_id="HDV4033322.1"
                     /translation="MGKNQEERKTPVIVVKKRRTFSPPSLSEKTDIIAPVFTEQTAES
                     APAGINSSAVETHIPEAPARKKKKKRHRFPRPSHWTREYTHECVEKIKALFPHLRAEG
                     GGFIPLKIGISNDISAFLAEHPETELTMDEWLCAVSCITSRRVYLQRTAVAGVPRYGL
                     DGHPKGQVSDSEAQSAGRRLATLEQKWLRTQAQQENISGQ"
     gene            958..1452
                     /locus_tag="RH288_004344"
     CDS             958..1452
                     /locus_tag="RH288_004344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001582574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033323.1"
                     /translation="MCDSEAEKILFILNKHERAYRRLIPVYIFLAIVLWILPILLIVY
                     LYFCIVDNEFLRIGFCIAWTAYYFLSLFKYFVKYFFPLDREDLLNLMDLAKDSPDAKQ
                     ELLERLLSGKRMTGRDEMDIKRILKTKEALDNIRNFIDKQQLTNSDTPKKSTVPNEDK
                     KGIR"
     gene            1452..1718
                     /locus_tag="RH288_004345"
     CDS             1452..1718
                     /locus_tag="RH288_004345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033324.1"
                     /translation="MLTGNGINTVTVNGKVKHITELDDITLCLEWTKLREENNRLYEI
                     NNQANRGWRGFILRLIGVNLPDKRTEFTQRLLLTRKISGSVMKK"
     gene            complement(2195..2668)
                     /locus_tag="RH288_004346"
     CDS             complement(2195..2668)
                     /locus_tag="RH288_004346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033325.1"
                     /translation="MRDKTREAMRLFLGGRCYTAEKLEKDYLAEVANYSNDRWEAPQR
                     ASRLAASVKRYKTSEMLRFIFATIAYDPDPDLTPLTVRRLCKALFGRTGSQWLVVEVF
                     GEKGRQHRSADSNPEMVEKMAARYRHAAELHWSATLAEIERVKRLYQTKIKKSKK"
     gene            complement(2785..3633)
                     /locus_tag="RH288_004347"
     CDS             complement(2785..3633)
                     /locus_tag="RH288_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001057990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDV4033326.1"
                     /translation="MNNDELATRRAQAIAEDRCFSKGRLRDEFRMKPAPGAEPVKWYK
                     NTYGGRFAVYRIADCVPMREKCPLTSKQQLAGQRLSVLSRLNSTSGRMARQAYDWLSL
                     APLFLDTETTGLDNTAEALEIGLTDAAGQVVFETRLKPTVAIGAQAAAVHGISEQALC
                     GAPSWTDVARQLRHAIGDRPVIIFNARFDIRILKQTAAAHSDPADWLEELTVYCAMEL
                     AAGYYGATYRYGTISLACAASQAGLTWEGQAHSAIADARMTAGVVNAIAAYHLELLQE
                     QARLKI"
     gene            complement(3673..3954)
                     /locus_tag="RH288_004348"
     CDS             complement(3673..3954)
                     /locus_tag="RH288_004348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001585073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDV4033327.1"
                     /translation="MMEIFWTMLASQDRKRIRKYIAEQNLMAAIELDERIGYSASSLA
                     GQPYKGRNGRVEGTRELVIHPHFVLVYEVDSQWGKVYILRVLHTAQKWP"
     gene            complement(3951..4220)
                     /locus_tag="RH288_004349"
     CDS             complement(3951..4220)
                     /locus_tag="RH288_004349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033328.1"
                     /translation="MAQVNMSLRIDAELKDAFMAAAKSMDRNGSQLIRDFMRQTVERQ
                     HNTWFRDQVEAGRQQLERGDVLPHDMVESSAAAWRDEMSRKVAGK"
     gene            complement(4275..4433)
                     /locus_tag="RH288_004350"
     CDS             complement(4275..4433)
                     /locus_tag="RH288_004350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001700046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033329.1"
                     /translation="MAESGYGLAGLGMGKVKSINQYRLTPGFGGFTPVSHVTTACRLP
                     CRWRGISW"
     gene            complement(5129..6160)
                     /locus_tag="RH288_004351"
     CDS             complement(5129..6160)
                     /locus_tag="RH288_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDV4033330.1"
                     /translation="MAGLKNTPYNAVHWSQLAPEEQIRFWEDYEAGRATTFLVEPERK
                     RTKRRRGEHSTKPKCENPSWYRPERYKALSGQLGHAYNRLVKKDPVTGEQSLRMHMSL
                     HPFYVQKRTYAGRKYAFRPEKQRLLDAVWPVLVSFSDAGTHTVGMSVSRLAREISPKD
                     SKGKVIPELEVTVSRLSRLLAEQVRFGVLGVSEETLWDRETRQRLPRYVWITPAGWQM
                     LGVDMVKLHEQQQKRLRESEIRQQLIREGVLREDEDISVHAARKRWYLQRSQDALKHR
                     RAKAAASKRARRLKKLPADQQIHEMAEYLRKRLPPDEAYFCSDDHLKRMAIRELRQLE
                     LTLAAPPPH"
BASE COUNT         1651 a         1658 c         1570 g         1726 t
ORIGIN      
        1 ccccccatga aacaaaggca gagatgaact gtgcgccccg atatcttctt ctgatatcct
       61 ttcaaatgaa ttgtttttat ttatatcatg acaacattaa agtgagagaa tatatcaacc
      121 atgtttctgt cagggttcag tagaatatca attcgactgt cacgccataa ctgtaactac
      181 ctcgagtata aatattcaga gaatggactt attagccatg aaaaatcacc tgatgggaaa
      241 tttactaatt tatggattgt gatattatta aagagtaaaa ccagccagcc gaggtattta
      301 tgggaaaaaa tcaggaagaa aggaaaactc ccgtcattgt ggtgaaaaaa cgtcgtactt
      361 tttcgccacc gtccttatcc gaaaaaacag atattatcgc acctgtattt actgaacaga
      421 cggcagaatc agcccccgcc ggaataaatt catctgccgt cgaaacacat atccccgaag
      481 cgccagccag gaagaagaaa aagaaaagac accgttttcc acgtccctcc cactggaccc
      541 gtgagtatac tcacgagtgc gtggaaaaaa taaaggccct gtttcctcat cttcgtgctg
      601 aaggtggtgg atttattccc ctgaaaattg gcataagcaa tgatatttcg gcatttctgg
      661 cagaacaccc ggagacagaa ctgaccatgg acgaatggct ctgtgcagtg tcctgcatca
      721 catcccgccg cgtatatctg cagcggacag ctgtcgccgg cgtcccacgt tatggcctgg
      781 atggtcaccc caaagggcag gtctcagact ctgaagcaca gagtgccggt cgcagactgg
      841 cgacattaga acaaaagtgg ctcaggacgc aggcacagca ggagaatatt tctgggcaat
      901 aaacactcct gataacaggt ggacattacg tatcagaaaa aatgggaaga gaatgttatg
      961 tgtgattcag aagcggagaa gattttattc atcctgaata aacatgaacg ggcatacaga
     1021 cgcctgatcc ccgtatatat ttttttagct atagtattat ggattttacc tattctcctg
     1081 attgtatacc tgtatttctg tatagttgac aatgagtttc tcagaatcgg tttctgtatt
     1141 gcatggacag catactactt tctttcgctt ttcaagtatt ttgtaaaata cttctttcct
     1201 ctcgatcgtg aagatttgct taacctgatg gatctcgcca aagattctcc tgatgcgaaa
     1261 caggagcttc ttgagcgtct tttgtccgga aaaagaatga ccgggcggga tgaaatggat
     1321 atcaagcgca ttctaaaaac aaaggaagca cttgataaca tcaggaattt tattgataaa
     1381 cagcagttaa cgaatagtga tactccgaag aaaagcacgg tcccaaatga agataaaaaa
     1441 ggcataagat gatgctcaca ggaaatggaa taaacactgt aactgtcaat ggaaaagtga
     1501 aacacatcac agaactggat gatataacac tttgtttaga gtggacaaaa ctacgagagg
     1561 aaaacaatcg tctttatgaa attaataacc aggcaaacag aggatggcgt ggtttcatcc
     1621 taagattgat aggggttaac ctgccagata aaaggactga gtttacacaa cgtctcttat
     1681 tgacgcgcaa aatttcgggt tcggtcatga aaaagtaaca aaaccgcgca acagacataa
     1741 atatgacagt agccatgaaa aagcagagag agacagggtg atacagaaaa gtaactattt
     1801 tttagctata gtattattgg ttttacctat ttttgtgatt ttatttctgt atatttgaca
     1861 atgagtctct cagaatcggt ttctcgaagt gacgagcgat cagaatggag acaaataaat
     1921 tcgggaaacg aaccttcacg gtaagttttg tcacatttat catccctaaa catgagaatt
     1981 atcaccaaaa ctaaccaccc aaccaacagc agcgccggga gcagcattat aaaatcatgt
     2041 acagagttgc gtgacgacat gataagttct cattctcaat atgttcttta ccagattata
     2101 ccagtgatac tttaacgcac catcattaat gctaatgtat gcatacatta acattaatga
     2161 tgaaggagaa gaacaacaat ggcagtcaac ccacttattt tttggatttc ttaattttcg
     2221 tctgataaag ccgctttacc cgttcaattt ctgccagcgt tgcggaccag tgtagttcgg
     2281 cggcatgacg atatctggca gccatttttt ccaccatctc cggattgctg tccgcgctgc
     2341 ggtgctgacg ccccttctcc ccaaaaactt caacaaccag ccactggctt ccggttctgc
     2401 cgaacaatgc cttgcacaaa cgtctcacag ttagcggggt taaatctgga tcgggatcgt
     2461 aggcaatggt agcaaaaata aagcgcagca tttctgatgt cttgtaacgc tttacgctgg
     2521 cagccaggcg tgaggcacgt tgcggtgctt cccagcggtc gttactgtaa ttagccactt
     2581 cagccagata atccttttca agtttttcag ccgtgtagca cctgccgcct aaaaaaagcc
     2641 gcatggcctc cctggttttg tctctcacat atcatccctc attaatgcta atgtacacat
     2701 acattagcat taacatgctg acagcaacaa gcggcggatt tacgtctgga taacgtaaat
     2761 gattgcggta tacaggccag gcggtcagat tttcagccgt gcctgttcct gcagcagttc
     2821 cagatgatat gcagcaatag cgtttaccac ccctgccgtc atccgtgcgt cggcgatcgc
     2881 tgagtgtgcc tgcccttccc aggtcagtcc ggcctgactg gcagcacagg ccagtgaaat
     2941 cgtgccatag cggtaggtgg ccccataata tcctgcagcc agctccatcg cacaatatac
     3001 cgtcagttct tccagccagt cagccggatc gctatgtgcg gcagcagtct gtttcagaat
     3061 gcggatgtcg aaccgggcat taaagataat tactggtcgg tccccgattg catgacgcag
     3121 ttgccgcgcc acatctgtcc atgatggtgc gccgcagaga gcctgctcgc tgataccatg
     3181 cacagcggcg gcctgcgccc cgatggcgac cgtgggcttc agcctggttt caaataccac
     3241 ctgaccggcc gcatcggtca ggccgatttc cagggcttcc gcggtattat ccagtcctgt
     3301 cgtttcagta tccagaaaga gcggtgccag actcagccag tcatatgcct gccgtgccat
     3361 ccggccactg gtgctgttaa gtctggataa aacggaaagt cgctggccag ccagctgttg
     3421 tttactcgtc agagggcatt tctcacgcat cggaacacag tctgcaattc ggtatacagc
     3481 gaacctgcca ccataagtgt ttttatacca cttaaccggc tcagcaccgg gggctggttt
     3541 cattctgaat tcatcgcgca aacgtccttt cgagaaacac ctgtcttcgg caatcgcctg
     3601 cgcacgtctg gtggccagct catcattatt catggttatt gcatctcctt tccttatatc
     3661 cggacagccc ctctatggcc acttctgtgc agtatgcaac acgcgcagga tatacacttt
     3721 tccccactgg ctgtcgacct cataaaccag aacaaaatgc gggtgaataa ccagttcccg
     3781 ggtaccttcc acacgaccgt tgcggccttt atacggctgc ccggccaggc tgctggctga
     3841 ataaccaatc cgttcgtcca gttcaatggc ggccatcagg ttctgctccg caatgtactt
     3901 acgaatgcgc ttcctgtcct ggctggccag catggtccag aatatctcca tcatttaccg
     3961 gcaaccttcc tgctcatttc atcccgccat gcagcagcgg aagattcgac catgtcatgg
     4021 ggaagcacat cgccgcgctc gagttgctga cgtcctgcct caacctggtc acggaaccag
     4081 gtattatgct gccgttcaac ggtctggcgc ataaaatccc gaattaactg agagccatta
     4141 cggtccatgc tttttgcagc ggccataaaa gcatccttca gttcagcgtc gattcttaaa
     4201 ctcatattaa cctgtgccat ttatcacctc gtcattacta cgtatataca cagtatataa
     4261 cgattcagat atcgtcacca ggatatgccg cgccagcggc atggaaggcg gcacgctgtg
     4321 gttacatgtg ataccggagt aaaaccgccg aagcccggcg tcagccggta ctgattgata
     4381 gatttcacct tacccatccc cagccctgct aagccatacc cgctttcagc catgagagag
     4441 tttctgtgcg cggtcggagt ggtcccgacg agggtttacc cgaagtcggg gcgtatctcc
     4501 gcgttagcgg gccgtcaggg ccgcttacga gcgtgtactg agaacatcca gccagaagac
     4561 tgacagcgat gataatgtag ttacaacatt cataattaaa agcgatgttg ttcccgccct
     4621 ttgggcgggg gcggcctcgc ttttcagtta tgaggggtgg gcacggtgct gcgtttgtgt
     4681 ggtgttttta ttcctgatgt ctttttgttg tggtttcaga acggtgaggt tcggggcccg
     4741 cgcgtcagcg tgggaggtgc ttttagattc tgagcggcgc ggccttggcc gctgcaagcg
     4801 aaggcctctt tgtatttgtt cacagtggtc tcagagataa agattttccc tgcggcgaag
     4861 caacgcaggg gattaaataa tggggttaag actatattgc aggtttgctg tttcaggttt
     4921 gcagcttctt aaagttcttt gtttgcggat ttatgtggat aactgaaaca acgtggccat
     4981 gttctgatga ctgatgcgtg gttttatggg cagatatgcc cctctgaggg gatttaaggt
     5041 gattactgcg gattttgggc tgagcggaac cagcgccgaa agccccggag gggctggtga
     5101 tgattcagtg ctgagggaat ggtgctgtct agtgcggtgg cggggcagcc agcgtcagtt
     5161 caagctgacg caactccctg atggccattc gcttcagatg gtcatcggaa caaaaatagg
     5221 cttcatccgg aggcagacgc ttcctgagat actctgccat ctcatgaatc tgctggtcgg
     5281 caggcagttt cttcaggcgt ctggcgcgct tactggctgc tgctttcgca cgacggtgtt
     5341 tcagcgcatc ctgactgcgc tgcagatacc agcgttttct ggccgcatgt acggagatat
     5401 cttcatcctc acgcagaaca ccttcccgaa tgagctgctg gcggatttca ctttcacgca
     5461 gtcgtttctg ctgctgttcg tgaagtttta ccatgtcgac gcccagcatc tgccagcctg
     5521 ccggtgttat ccagacgtaa cgtggcagac gctggcgggt ttcacggtcc cacagggttt
     5581 cctctgaaac acccagcaca ccaaaacgta cctgttcggc cagcaaacgg gaaaggcggg
     5641 agaccgtcac ttccagttcc ggaataacct tccccttgct gtctttcggg ctgatttctc
     5701 tggccagacg ggaaacactc atgcctacgg tatgtgtgcc cgcatcactg aagctgacca
     5761 gaaccggcca gacggcatcg aggaggcgtt gtttttccgg acggaaagca tatttgcgac
     5821 cggcatacgt tcgtttctgc acgtaaaaag gatgcagaga catgtgcatg cgcaggctct
     5881 gctcgccggt caccgggtcc tttttcacca gacggttgta ggcgtgcccg agctgcccgc
     5941 tcagcgcctt atagcgctca ggacgatacc aggacggatt ttcgcatttg ggtttggtgg
     6001 agtgctcacc acgacgacgc ttcgtgcgct tcctttccgg ttcaaccagg aaagtggtcg
     6061 cccttcccgc ttcatagtct tcccagaaac ggatctgctc ttcgggtgct aactgactcc
     6121 agtgtactgc gttatatgga gtattcttca gacctgccac aagctgtcgc ttatggcgga
     6181 gcgattgtgc cgtgtattta tacactgcac agggttgaat ctctggtacg gtttcattat
     6241 actttacccg tattctgtga ggcccccact atctttcgtc gttccgccaa gttcgtaaga
     6301 aagatagtgg gggttttcct tttatggctt ccggaacatc ttcagtcttc tgacttactg
     6361 cccgtacatg ccatctctcc tgaatgcctt atggcgcatt ctgccgtccg gctttcgccg
     6421 ctttgctcca cagagtgcca ccctctgcac agctaataac agccgaaata tacccgcttt
     6481 acgttaattt gaaaagcatt acaacgatct cttctcttcc agtgcctcct cactgatacc
     6541 tctaataagt taatcttgac ctgcgtcaaa aaaataaaat ctatttttaa aagcagattt
     6601 ttctg
//
LOCUS       DAPHKZ010000194         6462 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.195, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000194 DAPHKZ010000000
VERSION     DAPHKZ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6462
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.195"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..464
                     /locus_tag="RH288_004352"
     CDS             <1..464
                     /locus_tag="RH288_004352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416244.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033331.1"
                     /translation="TSVFRPEKMTNLISIKNRLVIHYLRTIYYEQNYIHPVGSIFAAI
                     QKNESLLKFPSIISMLNINLLFNPLNLPGMGSGVLEDIMSIPDSSLRKRLGYEVLSFS
                     LQAHSLSQECIDKLDIFFADDLFKYESVCIAAMEHLKSKATAPIQNGPLPA"
     gene            complement(468..1859)
                     /gene="tcyP"
                     /locus_tag="RH288_004353"
     CDS             complement(468..1859)
                     /gene="tcyP"
                     /locus_tag="RH288_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HDV4033332.1"
                     /translation="MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
                     LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLAA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFA
                     VHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKA
                     ILDSEDDAELAHH"
     gene            complement(1992..2582)
                     /locus_tag="RH288_004354"
     CDS             complement(1992..2582)
                     /locus_tag="RH288_004354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707386.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDV4033333.1"
                     /translation="MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLL
                     PDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLAVFALLATFYLKVPEGWFIPADA
                     LQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
                     WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY"
     gene            complement(2745..3413)
                     /gene="hxpB"
                     /locus_tag="RH288_004355"
     CDS             complement(2745..3413)
                     /gene="hxpB"
                     /locus_tag="RH288_004355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HDV4033334.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRN
                     ELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVIARAISLVEETRPLLPGVREAVA
                     LCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLADVKLSSLTELTAK
                     DLLG"
     gene            3560..4096
                     /locus_tag="RH288_004356"
     CDS             3560..4096
                     /locus_tag="RH288_004356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HDV4033335.1"
                     /translation="MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENKE
                     GINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQ
                     DSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
                     PVICIAAGYVFFSLLGFI"
     gene            complement(4137..4997)
                     /locus_tag="RH288_004357"
     CDS             complement(4137..4997)
                     /locus_tag="RH288_004357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDV4033336.1"
                     /translation="MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFV
                     KCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHS
                     AFILGQQIARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTEQPPQIYDGYQSVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIA
                     QQSLDRLLAA"
     gene            complement(5103..5393)
                     /gene="ghoS"
                     /locus_tag="RH288_004358"
     CDS             complement(5103..5393)
                     /gene="ghoS"
                     /locus_tag="RH288_004358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HDV4033337.1"
                     /translation="MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDEG
                     NIHELGTNTFGLISTQSEEEIRELVSGLTQSATGKDPEITITAWEEWNSNRK"
     gene            complement(5494..6423)
                     /gene="pfkB"
                     /locus_tag="RH288_004359"
     CDS             complement(5494..6423)
                     /gene="pfkB"
                     /locus_tag="RH288_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416237.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HDV4033338.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINV
                     ARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGE
                     QYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQG
                     IRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKA
                     KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR"
BASE COUNT         1679 a         1610 c         1571 g         1602 t
ORIGIN      
        1 tcacttctgt atttcgccca gaaaaaatga ccaatttgat cagtataaaa aacaggttgg
       61 ttattcacta tttaaggact atatactatg aacaaaatta tatacatcct gtcgggagca
      121 tttttgctgc gattcaaaaa aatgagagtc tcctaaagtt tccttcgata atatcaatgc
      181 ttaatatcaa tcttcttttt aatccactaa atcttccggg aatgggaagt ggtgtgcttg
      241 aagatattat gagtattcca gatagttcac ttagaaaacg tctcgggtat gaggttttaa
      301 gcttctcgct acaggcacat tcattgagcc aggaatgtat tgataagttg gacatttttt
      361 tcgctgacga tctgtttaaa tatgagtcag tatgcatcgc cgcgatggaa catttaaaaa
      421 gtaaggcaac ggcccctata caaaacggac cgttgccagc ataagaatta atggtgtgcc
      481 agttcggcgt cgtcttcgct atccagaatg gctttatcgg tttgcttcag ccactggctg
      541 gtcagcgtgc cagctgtcat cgagccacta acgtttaacg ccgtacggcc catgtcgata
      601 agcggttcaa cggagattaa cagcgccacc agggttactg gcaggcccat cgcaggcagt
      661 acaatcagtg cggcgaaagt tgcaccacca ccgacaccgg caacgcctgc ggaactaacg
      721 gtaacaatac cgaccagcgt cgcaatccac atcgggtcca gcgggttaat gccaaccgta
      781 ggcgcaacca tcaccgccag cattgccgga tacaaaccgg cgcagccgtt ctgaccaatg
      841 gttgcaccga aagaggcggc gaaactggcg atggattcag gaacgcccag acgacgcgtt
      901 tgtgcttcca cattcagtgg gatagacgca gcactggaac ggctggtaaa ggcaaacgtc
      961 agcacaggcc ataccttacg gaagtacttc agcggactca cgccattaat gcccagcaga
     1021 atgccatgca ctgcaaacat aatcagcaga ccgaggtagg acgcgacaac gaaacttccc
     1081 agtttgatga tgtcttgcaa gttagaacct gcaaccactt tggtcattag agccagaacg
     1141 ccgtaagggg tcaactgcat gaccaggcga accagtttca tcacccagct ttgtagggta
     1201 tcgatagcgg ctaagacgcg ttcacctttc ggcgcatcat ccttcagcag tttcaatgca
     1261 gctacgccga ggaatgcggc aaaaattacc acgctgataa ttgacgtcgg attggctccg
     1321 gtaagatcgg caaacgggtt tttcgggata aaggacaaga ccagctgcgg aacgctcaga
     1381 tcagagactt taccaacata gttactttca atggcgttca gacgtgcagt ttctgcacca
     1441 ccctgaacca gaccttcagc cgtcaaacca aacaggttgg tgaccagcac accgaccagc
     1501 gccgcaatca gcgtggtaaa caaaagcgta ccgatggtca gaaaactgat tttgcctaac
     1561 tgagatgcgt tatgcagacg ggcaaccgcg ctcagaatag aggcgaagac taacggcata
     1621 acgatcattt gcagcagttg aacatagccg ttaccaacga tgttaaacca ctgtacagaa
     1681 tctttaagta cctggctgtc agaaccataa atggtatgca gggcaaggcc aaaaaccaca
     1741 cccatcacca gacccaccag cacttttttc gccagactcc actgtttatg gcgggtctga
     1801 gccagcgcaa acagcagtac aacgaacacc acgatgttcg caattaatgg aaagttcatc
     1861 cccgttctcc tgatcttatt atttctatca ctgcgtagca gtcatagtgt tggcgcaaga
     1921 ttaacagaac tgtgagctgg ctcttatatt caaatggaat tgcttattcc agaaaggtga
     1981 tttttgcctt tttagtattc aacctgatgc ttaataagcc gatgaaactg gatctgcaag
     2041 gtattgatca tttgcgatga ccaacgaaca gcgctgttct cgggtaatga atggggcatc
     2101 cataccgacc agacaaataa tgccatgcag ataaaacgtt ccagttggtt gcccttttgg
     2161 ggaaccagga taggcaagcg gaaacgccag cggcatggcc agagcagggg aacaccggcg
     2221 ggtgtcagca tatcggcaag tatgtggctc aaataaccca gcaccattcc ttgtagcgca
     2281 tcagccggaa tgaaccagcc ttccggaacc ttaaggtaaa aggttgccag cagcgcaaat
     2341 accgccagca gactgtgggt aaaaccacga tgcccaaaag cgcgggcgat cggttttgat
     2401 atccatttta atcgctgccc aagaaacgac tttgggtgat cgatgtccgg taacaaacac
     2461 gtcaggattg cggaagggac aatatgccac cagtcaccct gtgccagcac gggcgtcagc
     2521 tcggcatttt tggcaaatac cgcacaagca atagaaaaga gaaggtgacc ttccgccgtc
     2581 atgataaaac tcactaaact gtcgatacgt acagtatagg atttttatac agtgcacgga
     2641 agtggtgacg gtgtaactct ttctcttaaa ttgacgatta atccgtcagt tgaatgcaat
     2701 ttcagataaa gaaccagggg cagcgagatc actgcccctg gtcattaacc gagaaggtct
     2761 tttgcggtga gttctgtcag cgatgagagt ttgacgtctg ctaatacaaa acgtggatca
     2821 ttttgcgctt ctggcgcagg aacgacgatg gaacgcatgc gggctgcttt agaggcgatc
     2881 atgccattta ccgaatcttc cagcgctacg caggtcagag ggtcaacgcc cagttttgct
     2941 gcgcagtcga gatatacttg cggatgcggc ttgctgtaag gcagtttttc ggccgaggcg
     3001 agggcatcga aactgtcgcg taagtcaaac atggtcaaca ctttttccag catatgtagt
     3061 ggtgacgcgg aggccagtcc caccaataaa ccttgttctt tgcataacgc aacggcttcg
     3121 cgcacgcctg gtaataatgg acgtgtctct tcaaccagtg aaatggcacg ggcaataacc
     3181 cgttctacta cttcctgacg gcttggccca ttccacggtt gccgggcgta ccaaagatcg
     3241 accaccatat cgatgcgtaa acctaaggtg tccggcagct cgttacgacg ggagatatcc
     3301 acccccaggc ttgccatcac atccagttcg gctcgatccc ataaaggttc tgagtcgata
     3361 agtaatccat ccatatcaaa aattgcagca agaatctgac gcggggttga cattacaacc
     3421 tctcctttag agcattatgt gtaaggtatt aagccgtgct tatgattaag cgcctatcat
     3481 atcgccttta aagaatgggc gaaaacagat atctacaggt aaactaagtg aaacgacgcg
     3541 tcttaatcaa ggagaactca tgacgtatca acaagctgga cgcattgctg ttttgaaaag
     3601 gattttgggt tgggtgattt ttatacctgc attgatctct acattgattt ctttgctgaa
     3661 atttatgaat acccggcagg aaaacaagga aggcattaat gcggtcatgc tcgactttac
     3721 tcatgtcatg atcgatatga tgcaggcgaa tacgcctttt ttgaatctat tctggtataa
     3781 ctccccgacg cccaatttta atggtggcgt gaacgttatg ttctgggtga ttttcatcct
     3841 gatttttgtc ggactggcgt tgcaggattc cggtgcccgg atgagtcgcc aggcgcgctt
     3901 cttgcgggaa ggtgttgaag atcaactcat tctggaaaaa gccaaagggg aagaggggct
     3961 aacgcgtgaa caaattgagt cccgtattgt tgttccgcac catactattt tcctgcagtt
     4021 tttctcactg tatatcctgc cggttatttg tattgctgca ggttatgtgt tcttttctct
     4081 gcttgggttt atttaatcaa aaggccgcac ggagcggcca ttatcctcaa cccatatcat
     4141 gctgctaata atctatccaa tgactgctga gcaataacca aatgctgacc gccaaataac
     4201 cttgcacgat ttaacagcgt gtagagttgg taaaccggtt gacgttcaag gaaatcggca
     4261 ggtagcgggg atactgactg atagccgtca tagatttgtg gcggctgttc agtatgcagc
     4321 ggtaacatcg ccaggtcgca ctctcggtca ccccagtagc aggccgggtc gaaaatgtac
     4381 gggccatccg gacccagtgc acagttgccg gaccataaat cgccgtgcaa cagagaaggc
     4441 tgcggttgat gtgaggccag acgctgctga atatgctcga cgatggcgtc gatattgccg
     4501 aaagcgatcc ctttttctgc agccagttcc aactgccagc caatccgttg ttcagcaaaa
     4561 aacgttgacc agcgacgttg ccaggtgttg ggctgtggag ttgtggagag cgcgttatcg
     4621 aaatcaaggc caaattgtgg ttggtcgctc cattgatgta aacgcgcaat ttgctgacca
     4681 agaataaatg cgctatgcgc atccagcgga cgaggtggga gataatccat caccagaaaa
     4741 ctgtagtcac ggtcagcgcc aactgcccaa accttaggca cggtgacggt tttactacgc
     4801 gacagtaact ccagttggtc ggcttcggcg gtaaaaccgg gaagcagttc cctttcatca
     4861 catttgacga aaaaatcatg tcctgcatag cgcaaatgcc atgcggcatg gacttctccg
     4921 ccaggcagtt cattacgcag ttcgatttcg ccttcaccta actgctcgct caaaagacga
     4981 ctgattgcct gccacatgat gtctctccca tgttgtctgc cagatcataa ggttagcgca
     5041 agaatgcggt gtaaaaacac gagctaacgc acaccacaga ctgattattg cccaaaaacc
     5101 atttattttc tgttgctatt ccattcctcc caggccgtga tggtgatttc aggatctttg
     5161 ccggttgcac tttgggtaag ccccgaaacc agttctctaa tttcttcttc actttgggta
     5221 ctgataagtc caaaagtgtt agttcccagc tcatggatat ttccctcatc atccgtcata
     5281 gtgagcaaaa aaccgtcgcg agtcaggtaa ttattcaact cgttaatttc agtcaatgta
     5341 tcctcatgca acatgacggt tatgacataa cggacaagat cgccactggc catagttcac
     5401 ccctttgtta tcacatgact tttgagcata gtcggagaaa cgcgttgccg acaggttggt
     5461 gatgattccc ccaatgctgg gggaatgttt ttgttagcgg gaaaggtaag cgtaaatttt
     5521 ttgcgtatcg tcatgggagc acagacgtgt tccctgattg agtgtggctg cactccccgc
     5581 agctacgcca aaacgaacca tctcttcaag agaggcattt tctgccagtt tcagtgtcat
     5641 cgcgccgacc atgctgtcac cagcgccaac ggtactctgg cttttcaccg gtggtggcac
     5701 cacctgaata cagttttcac tatcaacacc cagcgctcct tgtggaccca gggaaacgac
     5761 aacccgtttg gccttgccgc tattaacgat ttcctgcgcg gctttgcgga catcgtccgg
     5821 ctgggtgagt tcgcgattca ccagcgcact gagttctttt tggttaggct taaccaactc
     5881 gatgttacca attgccagtg ctgcacttaa cgcttcgcca gaactgtcga cgatgcagcg
     5941 gatcccttgt ttttgcgcag cggaaatcag ttgggttaat ttttccagct tcacacctgg
     6001 cggcaggctt ccgcttatga ccaggatggc cccggattca atttccagaa cttgctcttc
     6061 aagctggcga aactcatctt catttaatgc cgcgcctggc ataacaaaac gatactgctc
     6121 accgcttgct tccacatgta cgtgtaaatt ctgccgggtc cagtctttgg cttctacagt
     6181 agcgacgggg acattttcat ccgccaacag tgaaaccagg tgttcgccgg tcgcgccacc
     6241 cgccgggaag atcgctgtgg cactgcctcc aagatgggca atggcgcggg cgacgttgat
     6301 gccgccgccc ccgggttcga acaccggtgc ggtacagcgc agttttcctt cgggataaat
     6361 ttgcggggta attgttgcgc tatcgagaga gggcgcaagt gtcaacgtat agatacgtac
     6421 catcatttcc tcctataggc tgatttcagt ctggcaccga at
//
LOCUS       DAPHKZ010000195         6341 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.196, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000195 DAPHKZ010000000
VERSION     DAPHKZ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6341
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.196"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(256..1926)
                     /gene="betA"
                     /locus_tag="RH288_004360"
     CDS             complement(256..1926)
                     /gene="betA"
                     /locus_tag="RH288_004360"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HDV4033339.1"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDMGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKK"
     gene            complement(1940..3412)
                     /gene="betB"
                     /locus_tag="RH288_004361"
     CDS             complement(1940..3412)
                     /gene="betB"
                     /locus_tag="RH288_004361"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HDV4033340.1"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWASMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTE
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
                     MSILTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     gene            complement(3426..4013)
                     /gene="betI"
                     /locus_tag="RH288_004362"
     CDS             complement(3426..4013)
                     /gene="betI"
                     /locus_tag="RH288_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414847.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BetI"
                     /protein_id="HDV4033341.1"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPREQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKTRANSLTRHFITQHLPTD"
     gene            4142..6175
                     /gene="betT"
                     /locus_tag="RH288_004363"
     CDS             4142..6175
                     /gene="betT"
                     /locus_tag="RH288_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HDV4033342.1"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
BASE COUNT         1302 a         1743 c         1751 g         1545 t
ORIGIN      
        1 aaatctcaat cagatcgata tcctgtttga tttgttcacg cataatatat ccagagaata
       61 aaatctgtcg cagataaggt tgtattaata gtctgtatca ggaatgttcg ggttaaatat
      121 cagcaaaaag cccgcatcat gaatactgga tatgaagcat gagagttacc tcagtgttta
      181 tataaggatt cggtccccct ctctggaacg gtaactctca atctgatcgg ttcctgcgtt
      241 agttcacatc acgactcatt ttttcgctct caccggcatc ccatttgcca caaaatatcc
      301 cgccgtgctc ctcggcagcg cttcctgtcc acgaatcata tccgctattt tctcgccaat
      361 cataattgtc gtggcgttca aattcccggt gataatctgc ggcataatcg acgcatccac
      421 cacacgcagg ccttctaacc cgtgtacgcg gccttcgccg tcaaccacgg acatctcgtc
      481 gtaacccatt ttgcaggtac cgcacggatg gaaggcggtt tcggcgtggt tacgcacgaa
      541 ctcatcgagc tgttcatccg tctggcattc gacaccgggg ctgatttcgc ggccacgata
      601 ctgatccagc gcgggttgat gcatgatctc gcgggtgatg cgaattgcgt cgcggaactc
      661 ctgccagtcc tgctcgtgcg acatgtagtt aaacagaatc gccggatgct ggtgcgggtc
      721 gcgggattta atccgcacat gcccacggct tggcgagcgc attgagccga cgtggcactg
      781 gaaaccgtgc tctttcactg cattcgagcc gttatagtta atcgctactg gcaggaaatg
      841 gtactgaata ttcggccacg caaattcctc acggctgcga ataaatccac ctgcttcaaa
      901 gtggttgctg gcaccaacgc cagtgccgcc aaacagccac tccgcaccga ttttcggctg
      961 gttccaccac tgcagggcag ggtagaggga aaccggttct ttgcactcat attgcagata
     1021 catctccaga tgatcctgaa gattttcgcc gacgccgggt aattcatgca ccagcggaat
     1081 atcaaactcc gccagcagtt cagcgttgcc gacgccggag cgttgcagga tctgcggtga
     1141 ggcaatcgcg cctgcacata acagcacttc tttgttggcc gttgcgcggg ttgggatggt
     1201 gctgtcgcct tccagccatt cgacgcccac cgcgcgtttg ccgtcaaaaa tgatgtgatc
     1261 ggtcatagcg tgagtacgaa tggtcaggtt aggacgcgat ttggcctgat cgagatagcc
     1321 acgcgcggtg ctggcgcgac ggccctgcgg cgtgacggtg cgatccatcg gaccaaaacc
     1381 ttcctgctga taaccgttga gatcgtccgt gcgcgggtag cccgcctgca cgcccgcttc
     1441 aatcatcgct tcaaacagcg gattgacgcc gggtttggag gtagtgacgc tcaccgggcc
     1501 atcaccgccg tgatagtcgt tttcacccat atcgcgagtc tcggccttgc ggtagtaggg
     1561 caggcagtcg aggtagctcc agttctccag accgggttct tgcgcccagt tatcgagatc
     1621 cagcgcattg ccacggatgt agcacatgcc gttgatcagc gacgatccac ccagaccttt
     1681 accgcgtccg cactccatgc ggcggttatt cataaacggt tcaggttccg tttcataggc
     1741 ccagttgtag cgtttaccct gtagcgggaa tgccagggca gcgggcatct gggtgcggaa
     1801 gtcaaagcga tagtccgggc cgcccgcttc aagcagcagc acggaggtat tcggatcttc
     1861 agtcagacgg gtagcgagaa cgttgccggc tgagccggca ccaataatga tgtagtcaaa
     1921 ttgcaaataa acctcctggt tagaatatgg actggaattt agccatctca acctggatgg
     1981 acttcacctg ggtgtaactc tggagcgtca tcacgccgtt ctcgcgacca atgccggagt
     2041 gtttgtagcc gccaacgggc atctctgccg gggattcgcc ccaggtgttg atccagcaaa
     2101 tacccgcttc cagctgatga atgacgcgat gcgcgcggtt caggtccgct gtcacgatgc
     2161 ccgccgccag gccgtagtcg gtatcgttag cgcggcgaat gacttcgtct tccgactcgt
     2221 aggtcagaat ggacatcact ggcccgaaga tctcttcacg cacgatggtc atatcgtcgc
     2281 tgcaatcggt gaacactgtc ggtgcaaccc atgcgccgtt atcgaagcca tcgcctttca
     2341 gtacatcgcc gccgcacagt acgcgcgcgc cttcctcttt gcctttggcg atatagcgca
     2401 gcacgttatc gcgatgcggg aagctgacca gcgggccgaa gttagtttgc ggatcgaaaa
     2461 cgtcgcccgc gcgaatgcgc tcaacgcgcg ccagaatttt ctgctcaaat gcggctttgc
     2521 atttcgccgg aacgaagacg cgggtgccat tggtacacac ctgaccggag ctgaagaagt
     2581 ttgccatcat ggcgatatcg gcggcgagat cgagatccgc atcatcgaaa acgatcagcg
     2641 gtgatttacc gcccagttcc atggtcactt ctttcaggga agaggccgcc gagttagcca
     2701 tcactttttt gccgctggcg acaccgccgg taaatgacac tttggcaatg cccggatgct
     2761 cggtcagata ttgcccggtc tccgcgccca cgcccggcaa cacgttaaat acgccgtccg
     2821 gcaggcccgc ttcgctgtaa atttcagcca gctttaacgc ggtaagcggg gtaacttcgc
     2881 tcggtttgaa aatcattgcg ttgcctgccg ccagcgccgg ggcggatttc cacagggcaa
     2941 tctggatcgg gtagttccat gcgccaatcc ctgccactac gcccagcggt tcgcggcggg
     3001 tatacacaaa ggacgtttca cgcaacggga tctggctgcc ttccagcgcc gggatcagcc
     3061 cggcgtagta ctccagcacg tccgcaccgg taacgatatc gacggttgag gtttccgaat
     3121 atgcttttcc ggtgtcgagg gtttccagtt ttgcgagttc gtcattgcgt tcacgcagaa
     3181 tatcaacggc ccgacgcaga atacgcgagc gctccatggc ggtcatcgac gcccagattt
     3241 tttgcccctg ctgggcgctt ttcacggcgc gatcgacatc ctcgcgcccg gcggcctgca
     3301 cggtcgccag cacgttaccg ttggccgggt taatggtctc gaaggtgcga ccgctggtgg
     3361 cggaggtata accaccatgt atataaagct gctgttctgc cattcgggac atcacgtctc
     3421 ctcggttaat cggtgggtag atgctgagtg ataaagtggc gggtcaggga attagcgcgg
     3481 gttttatcca gcggtttgcc gctcagagcc gcgcgcagcc ataatccatc aatcagcgcg
     3541 gccaggccgt agcccgcttc ctgtgcctgt tcgcgcggca attcgcgacg aaactcgctc
     3601 accagattcg acagcaagcg gcggctgctg acctgctgta aacgatagag catcggctga
     3661 tgcatactgc tggcccagaa cgccagccag gctttcatcg ccgcactgct cacctgcgtt
     3721 tcatcgaagt ttccgccaac aatcgcctgt aatcgctgct ctgcactgcc ctgcggaagt
     3781 gcatgtaatc gattcaaaac cgcgtcacgc agctgactgg tgatatcgcg catggttgct
     3841 tccagcagac catttttgtc cctgaaatag tggctgatga tccccgtaga aacgcctgca
     3901 cggcgggcga tctgcgcgat cgttgcatcg tgcatgccca cttcatttat tgcttccagt
     3961 gtggcgtcga tcagttgtct gcgccggatc gactgcatcc ccaatttggg cattttcgcc
     4021 actccattca tcagcggtgt ttatctatta aagcggttat tgattggacg ttcaatataa
     4081 aatgtgtctt aattgttacg aatttgattt taaatagtaa caataacagt ggggatactg
     4141 gatgacagac ctttcacaca gcagggaaaa ggacaaaatc aatccggtgg tgttttacac
     4201 ctccgccgga ctgattttgt tgttttccct gacaacgatc ctgtttcgcg acttctcggc
     4261 cctgtggatt ggccgcacgc tggactgggt ttctaaaacc ttcggttggt actatctgct
     4321 ggcggcaacg ctctatattg tctttgtggt ctgtatcgct tgttcgcgtt ttggttcggt
     4381 gaagctcggg ccagaacaat ccaaaccgga attcagcctg ctgagttggg cggcgatgct
     4441 gtttgctgcc gggatcggta tcgacctgat gttcttctcc gtagccgaac cggtaacgca
     4501 gtatatgcag ccgccggaag gcgcgggaca gacgattgag gccgcgcgtc aggcgatggt
     4561 ctggacgctg tttcactacg gcttaaccgg ctggtcgatg tatgcgctga tgggcatggc
     4621 gctcggatac tttagctatc gttataattt gccgctcacc atccgctcgg cgctgtaccc
     4681 gatcttcggt aaacggatta acgggccgat aggtcactca gtggatattg cagcggtgat
     4741 cggcactatc ttcggtattg ccactacgct cggtatcggt gtggtgcagc ttaactatgg
     4801 cttgagcgta ctgtttgata ttcccgattc gatggcggcg aaagcggcac tgatcgcctt
     4861 gtcggtgata atcgccacga tctctgtcac ctccggtgtc gataagggca ttcgcgtgtt
     4921 atcggagctt aatgtcgcgc tggcgctggg attgatcctg ttcgtattgt ttatgggcga
     4981 cacttcgttc ctgcttaatg cactggtgct gaatgttggc gactatgtga atcgctttat
     5041 gggcatgacg ctcaacagtt ttgccttcga ccgtccggtt gagtggatga ataactggac
     5101 gctcttcttc tgggcatggt gggtggcatg gtcgccgttt gtcggcttgt tcctggcgcg
     5161 tatctcgcgt gggcgtacca ttcgccagtt cgtgctgggc acgttgatta ttccgtttac
     5221 cttcacgctg ttatggctct cggtgttcgg caatagcgcg ctgtatgaaa tcatccacgg
     5281 cggcgcggca tttgccgagg aagcgatggt ccatccggag cgcggcttct acagcctgct
     5341 ggcgcagtat ccggcgttta cctttagcgc ctccgtcgcc accattactg gcctgctgtt
     5401 ttatgtgacc tcggcggact ccggggcgct ggtgctgggg aatttcacct cgcagcttaa
     5461 agatatcaac agcgacgccc ccggctggct gcgcgtcttc tggtcggtgg cgattggcct
     5521 gctgacgctc ggcatgctga tgactaacgg gatatccgcg ctgcaaaaca ccacggtgat
     5581 tatggggctg ccgttcagct ttgtgatctt cttcgtgatg gcggggttgt ataaatctct
     5641 gaaggtagaa gattaccgcc gtgaaagtgc caaccgcgat accgcaccgc gaccgctggg
     5701 gcttcaggat cgcctgagct ggaaaaaacg tctctcgcgc ctgatgaatt atccgggcac
     5761 gcgttacact aaacagatga tggagacggt ctgttacccg gcaatggaag aagtggcgca
     5821 ggagttgcgg ttgcgcggcg cgtacgtgga gctaaaaagc ctgccaccgg aagagggaca
     5881 gcagttgggt catctggatt tgttggtgca tatgggcgaa gagcaaaact ttgtctatca
     5941 gatttggccg cagcaatatt cggtgccggg ctttacctac cgcgcacgca gcggtaaatc
     6001 gacctactac cggctggaaa ccttcctgtt agaaggcagc cagggcaacg acctgatgga
     6061 ctacagcaaa gagcaggtga tcaccgatat tcttgaccag tacgagcggc accttaactt
     6121 tattcatctc catcgtgaag cgccgggcca tagcgtgatg ttcccggacg cgtgattgtt
     6181 attgcataaa accgcgccat gtctgcatat ggcgctgttt ctcctacctc ttgatacgtt
     6241 atatctatac ggttaagccc ttagtatcta ttgatgatta ccagacaaca gataataaaa
     6301 aagaaaagaa ctattgcagc ccaaaaccta catttgggct g
//
LOCUS       DAPHKZ010000196         6187 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.197, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000196 DAPHKZ010000000
VERSION     DAPHKZ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6187
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.197"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(175..537)
                     /gene="queD"
                     /locus_tag="RH288_004364"
     CDS             complement(175..537)
                     /gene="queD"
                     /locus_tag="RH288_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708563.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HDV4033343.1"
                     /translation="MKTTLYKDFTFEAAHRLPNVPDGHKCGRLHGHSFVVRLEITGEV
                     DKHTGWIIDFAELKAIFKPTLDRLDHYYLNDIPGLENPTSEVLAEWIWKQIKSQLPHL
                     TAVMVKETCTAGCIYRGE"
     gene            complement(631..1798)
                     /locus_tag="RH288_004365"
                     /pseudo
     CDS             complement(631..1798)
                     /locus_tag="RH288_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1872..3416
                     /locus_tag="RH288_004366"
                     /pseudo
     CDS             1872..3416
                     /locus_tag="RH288_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001710491.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KAP family P-loop domain protein"
     gene            3416..4168
                     /locus_tag="RH288_004367"
     CDS             3416..4168
                     /locus_tag="RH288_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033344.1"
                     /translation="MGTSQSSKGPGGGSPLVPPWADDQPQQPLPSPQERRFAPFRESL
                     GNAVSNGNRADFRKAIGHYARKASGGSSNAARRLGSVTQAGAELFGALVGMPSAPGEP
                     SIDLGSLAGLPCEIAISTIAQALTSQDGDSEKICAAMNHALVEALDGVEIFDPQKITD
                     GVIVDTMIGYLAESIFLQMVMDSNRAWNKADTPSKAIHAEIELRELIKVVVDKHMAPK
                     LAGNIRSFTRNQMVKIERQAIIEAWQEWEAYQ"
     gene            4150..5469
                     /locus_tag="RH288_004368"
     CDS             4150..5469
                     /locus_tag="RH288_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011076665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDV4033345.1"
                     /translation="MGGIPVTQLVFHHKHHHLPPASEKVLPVQLYGLSGQRRGDISVI
                     GNPAIDRIRRLGVQLPAKVMDFLSVALAVTAADTFVQRESSEDGWTRQLSLRLPLHEP
                     SRWISLKKELESALHFLSGDIWDFEFCDDGYAPPEPYSQHSRHRLIKLKGLDCVSLFS
                     GGLDSAIGAIDLLAAGRAPLLVSHAYKGDKSRQDQIAEKLSGQFSRFEINADPHIYQG
                     VTDITMRTRSLNFLAFAAVGACAVQEISQQEKIDLFVPENGFISLNAPLTPRRIGSLS
                     TRTTHPHFITSIQKIFDALGISCQIINPYQFKTKGKMISECSNKQLLSKIVESTVSCS
                     HWKRMGQQCGVCIPCIIRRASLHAGGISRDVEYIFQSLAKVMNEIDRRDDLIALRIAI
                     TQKSTLKIGTWIAKSGPLPTAEFDNFKQVFKDGLDEVESYLLSENIV"
     gene            5466..>6187
                     /locus_tag="RH288_004369"
     CDS             5466..>6187
                     /locus_tag="RH288_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDV4033346.1"
                     /translation="MSIDMHCHLDLYPRPDLVAEESKRRGTYILSVTTTPKAWHGTSL
                     LAKESQRIRTALGLHPQIAHQRSHELDLFDSLLSETKYVGEIGLDGGQGFKEHWDIQL
                     KVFRHILNSVNRAGGKIMTIHSRGSASAVLDEIENIDGVAILHWFTGTPKQLERAIDL
                     GCWFSVGPAMLDTIKGKALVLKIPKSRILTETDGPFAKFRNDPLMPWDSGIAEKQLAA
                     LWGISQMEVNAQLVDNFKVLCTS"
BASE COUNT         1699 a         1317 c         1469 g         1702 t
ORIGIN      
        1 ttgttaagta ataataaaat gatcaccatc gaatattaaa tattcatatc aacgccacta
       61 aggaaaacat aaactgccga gaattgtgat gcaagttata aaatggaagg ttgtttgttg
      121 ccatcgacta aggaatgtga ctggttttat ccaaaccagt catcgggtcg gatatcattc
      181 accgcgataa atgcaacccg ctgtgcaggt ttctttcacc attacagcgg tcaggtgtgg
      241 caactgtgat ttaatctgct tccaaatcca ttctgccagt acttcgctgg tcgggttttc
      301 cagaccagga atatcgttga ggtagtagtg atccagtcgg tctagcgtgg gtttgaaaat
      361 cgccttcaac tcggcaaaat cgattatcca accggtgtgt ttatcgacct ctccggtaat
      421 ttccagacgt accacaaaag agtgtccgtg caaacgccca catttatgcc catcaggcac
      481 gtttgggagt cggtgtgcgg cttcaaaggt gaaatctttg tacaatgttg ttttcatagc
      541 gacctcgttt tttgttatat agtaacaaca agaagcaaga cttcctagaa tttatgactt
      601 agtgattaac actactgtat tgtgtagtgg tcaacaaaaa ctggtcacaa tttcagattt
      661 tttccagtat ctattttccg attcgttcgg aggtaatcca ccgttatatt catgaggccg
      721 gagtgcactt aatattcaat tatatactct gttattgtat ggacaccttc gttaaggcta
      781 aagtaaccag tcactggtgc ccactcgttc ttcagacttc tgaagaaacg taccattagg
      841 ctaatatccc agcagtttcc ccgacgactc atactctcct tgatccgata acgccacatc
      901 acctgcctga actgcctgct cgtataatga ctaccctgat cgctgtggaa catcaccccg
      961 ccgggtttac cacgggtttc ccatgccatt tccagcgctt tcatggtgag cctgctgtcc
     1021 ggcgagaacg acatggccca gcccactggt tttcttgcga acaggtcgag aacaacggcg
     1081 aggtacgccc agcgcttacc cgtccagata taggtcacat caccgcacca cacctgattt
     1141 ggctcggtca cggcgaactg ccgttcaagg tagttaggga tagcaacatg ttcatgacca
     1201 ccacgtttat accggtgagt cggctgctga cagctgacca gccccagctc tttcatgagc
     1261 ctgccagcaa gccagcgtcc catctggtag cctctccggg ttgccattgt ggcaatgctt
     1321 cttgctccgg ccgaaccgtg gctgatgcca tgtagctcaa gtacctgact gcgtaataca
     1381 gcccgtctgc cgtctggttt ttcaggacgg tttttccagt atctgtagct gctgcgatga
     1441 accccgaaca catggcagag tgtggccaca ggataatgcg ctctgagttt cccgattatc
     1501 gagaactgtt cagggagtct gacatcaaga gcgcggtagc cttttttaat atttcatttt
     1561 ccatttcaat acgttgtagc tttttcctca gctcacggat ttcaatttgt tccggggtaa
     1621 tgggggaggc ttttggtgtt ttgccctgac gctcatcacg cagttgtttg acccatcttg
     1681 tcattgtgga aaggccaaca tccatagctt tggcggcatc tgccaccgtg tagttctggt
     1741 caacaaccag ttgagcggat tcgcgtttaa actctgcgct gaaatttctt tttttcattg
     1801 gagcacctgt gttgttctga ggtgagcata tcacctctgt tcaggtggcc aaattcagtg
     1861 tgccacttca tgccgcactt cttgaagtca tcgctacaga attgacaaaa gctgctgaag
     1921 gtaattctac ccttatatca aaaactaaga gactccttag tcgagttgat ggttttagag
     1981 ctatgggatt actagctgag ggtacagctt taatggcagg attacctact ggcggtttgc
     2041 tttctagggg gattggtgca ttaagaaata tcaccgatgg catccagagc caggaagagt
     2101 atgaggcttt aggcaatata gctaaagaag gtaaagaaac tgcttgtggt ttgattaaac
     2161 cacaaacaaa aaaaagcccc cctcagcaga ttgatgcctt tcgtaaggaa tatggggaaa
     2221 ttctagaaga acttggaaag ccactcattg tggtaataga taacctagac cgctgtctcc
     2281 ctgccaatgc tatccataca cttgaagcta tcaggctatt ccttttcttg actaatacag
     2341 cctttattat tgcagcagat gaggacatga ttcgctcttc tgtggctgat tacttcaaag
     2401 gggcatcaca gcgccatcaa atagattatc tggataagct aatccaggtt cctattcggg
     2461 tgcctaaggc tggggtccgt gagatccgtt cgtatctgtt catgctttat gccattgaac
     2521 atggcttaga aggcgaaaaa ataactatgc tccgtgaggg cttagagaag gcgttacagc
     2581 aatcctggaa agatgaacca atctcacgtc aggaggcctt aaaaatgact ggtgaagcgg
     2641 atgatagcaa cctcgcgctg gcgtttgcgc gtgctgaccg tattgctccc attttagcca
     2701 actctccaat tattcatggt aatcccagga tcgttaaacg cttgttgaat gttgtgaaaa
     2761 tgcgatctca aattgcgaag cgacgagcaa tgcctttgga tgaagcaatt attactaagc
     2821 tagtaatttt tgaacgctgt gttggagtgg atggcaccgc tgatttatat catctcgtgg
     2881 atattgaaca aggtgttccc cagatactta aacagcttga cgataatggc ggtcaaatac
     2941 ctactgatgc accaaagaca tggactgata gtccaacgac taaatctttc atcagtcaat
     3001 gggcccaact tgaacctcgt cttggtggga ttgacttaag ggccgccata tatctgtccc
     3061 gagaaactat gccaataggt gcatatgtgg ttggtttatc gccatctgga cgggaagtac
     3121 taaatgcact aattgaattg aaaaacacta gttctcctac agcagaaaac cttttgaaag
     3181 cacttcctcg tgaggagcaa atacctgtaa tggaaggttt aattaaccag ttacggcagg
     3241 tatcagattg ggatcgtaag cccagaggct tttccggcgc atgtctgttg gcccgctact
     3301 caacagatgc agccagcata ttaattcgtt atctacagga attacagttg gggatgaaac
     3361 gaccagcgtg gatgactgca gcattaaaag atgaacaatg gaataaggac gcttaatggg
     3421 aacatcacaa tcaagtaaag gtccaggagg tggctctccg ctggttccac catgggctga
     3481 tgatcagcca cagcaaccgt taccctcgcc gcaagaaagg aggtttgcgc catttcgaga
     3541 atcgttggga aatgcggtat caaatggaaa tcgagcagat ttcagaaaag ccatagggca
     3601 ctacgcgcga aaagcctccg gagggagcag taacgctgct cggcgattag ggagtgtcac
     3661 gcaagctggg gccgaattat ttggggcttt agtgggaatg ccttcggctc ccggagaacc
     3721 aagcatcgat ttgggcagtt tggcaggcct tccatgcgaa atagcaatat caactattgc
     3781 tcaagcttta acatcacagg atggtgactc agaaaagatc tgtgcggcca tgaaccatgc
     3841 tttagtggag gctcttgatg gcgtagaaat tttcgatcct caaaaaataa ctgatggtgt
     3901 gattgttgac acaatgattg gttatctagc ggaaagtatt ttccttcaga tggtaatgga
     3961 ttctaatagg gcatggaaca aagcagatac accttcaaag gcaattcatg cagaaattga
     4021 actccgggaa ttgattaaag ttgttgttga taaacatatg gcaccaaaac ttgccggtaa
     4081 cataagatcg ttcacacgaa accaaatggt aaaaattgaa cgtcaggcca ttattgaggc
     4141 ctggcaagaa tgggaggcat accagtgaca caattagttt tccatcataa acatcaccat
     4201 ttgccgccag caagtgagaa agtgttacct gttcagctat atggattaag tggtcagagg
     4261 cgcggagata tatctgttat cgggaatcct gcgattgatc ggatcagacg tttgggagta
     4321 cagcttccag ctaaggtcat ggattttctg agtgttgcat tagcagtaac tgcagcagat
     4381 actttcgttc agcgtgaaag ttccgaggat ggttggaccc gccaattgtc gttacgactc
     4441 ccccttcatg aaccatccag atggattagt ctaaagaaag aacttgagag tgctttgcat
     4501 tttcttagtg gagacatctg ggatttcgaa ttttgtgacg atggttatgc accgccagag
     4561 ccttatagcc agcattcaag gcatcgtctg attaagctaa aagggcttga ctgtgtcagc
     4621 ttattttcag gaggtctgga ttcagctatt ggtgcaatag atcttctggc tgcagggcgc
     4681 gctccacttt tggttagtca tgcttataag ggggataagt ctcgtcaaga tcagattgct
     4741 gaaaaattaa gtggccaatt ttcgcgcttt gagattaatg ctgacccaca catttatcaa
     4801 ggcgtgactg atattacgat gcgaactcgt agcctcaatt ttcttgcctt tgcggccgta
     4861 ggtgcttgtg ccgtacaaga gatatctcaa caagaaaaga ttgatttgtt cgtacctgaa
     4921 aatggattta tctcattaaa tgcaccactt actccacggc ggataggttc gctgagcaca
     4981 cgaacaacac atccacattt tattacgagc atacaaaaga tctttgatgc gctcggtatt
     5041 tcttgtcaaa taatcaatcc atatcagttt aagacaaaag gaaaaatgat ctccgaatgt
     5101 tcaaataagc agctcttatc taaaattgtg gaaagtacag tatcctgcag tcattggaaa
     5161 cgaatggggc agcaatgtgg ggtatgtata ccgtgtatca ttcgacgagc atcacttcat
     5221 gcagggggaa ttagtagaga tgttgaatat attttccagt ccttagctaa agtaatgaat
     5281 gaaatagatc gcagggacga cctgatcgcc cttaggattg cgatcacgca gaaatcgact
     5341 ttgaaaatag gtacatggat tgccaaaagt ggccctttgc ctacggcaga atttgataat
     5401 ttcaagcaag tatttaagga tggcctggat gaggttgaaa gctatttact gagtgagaac
     5461 atagtatgag catcgatatg cactgtcatc tcgacttata tcctcggcca gacctcgtgg
     5521 ctgaagaaag taaacgtcga gggacttata ttctgtcggt gacaacaaca cctaaagcat
     5581 ggcatggtac ttctttattg gctaaagaaa gtcaacgaat ccgaactgct cttgggctac
     5641 atcctcaaat cgcgcatcaa agatcgcatg agttagacct gtttgattca ttgctttcgg
     5701 aaactaagta tgtaggggaa atagggcttg atggtggaca gggatttaaa gaacattggg
     5761 atattcaatt gaaagtgttc cgacacattc tcaacagtgt aaatcgggct ggtggcaaga
     5821 ttatgactat ccatagtcgg ggaagtgcat cagcggtgct tgatgagatt gaaaatatcg
     5881 atggggtggc aatattgcat tggttcactg gaacacctaa gcagcttgaa agggcaattg
     5941 atttaggatg ctggttctca gtggggcctg ctatgctcga tacaataaag ggtaaggcct
     6001 tagttttgaa aatacccaaa tcacgcattc ttacagaaac agatgggcca tttgctaagt
     6061 ttcgtaatga cccactaatg ccatgggata gtgggattgc agagaaacag ttagccgcat
     6121 tatgggggat tagtcagatg gaggttaatg ctcagctagt tgataatttt aaggtattat
     6181 gtacatc
//
LOCUS       DAPHKZ010000197         6109 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.198, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000197 DAPHKZ010000000
VERSION     DAPHKZ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6109
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.198"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            247..1377
                     /gene="ompC"
                     /locus_tag="RH288_004370"
     CDS             247..1377
                     /gene="ompC"
                     /locus_tag="RH288_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HDV4033347.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNKSEDGDQTYVRLGFKGETQVTDQLTGYGQWEYQIQGNTSEDNKENSWTRVAFAGL
                     KFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFG
                     LVDGLNFAVQYQGKNGSVSGEGMTNNGRGALRQNGDGVGGSITYDYEGFGIGAAVSSS
                     KRTDDQNGSYTSNGVVRNYIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSL
                     GWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGVINGRNYDDEDILKYVDVGATY
                     YFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF"
     gene            1489..2544
                     /gene="apbE"
                     /locus_tag="RH288_004371"
     CDS             1489..2544
                     /gene="apbE"
                     /locus_tag="RH288_004371"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HDV4033348.1"
                     /translation="MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGT
                     FWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEA
                     MADIVTTSLRIGARTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
                     LTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALNSR
                     GMNGEGQPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQ
                     TGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVYMITKEGDSF
                     KTWMSPQFKSFLVSEKN"
     gene            2618..3682
                     /gene="ada"
                     /locus_tag="RH288_004372"
     CDS             2618..3682
                     /gene="ada"
                     /locus_tag="RH288_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HDV4033349.1"
                     /translation="MKKATCLTDDQRWQSVLARDPNADGEFVFAVRTTGIFCRPSCRA
                     RHALRENVSFYANASEALAAGFRPCKRCQPDKANPRQHRLDKITHACRLLEQETPVTL
                     EALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRESLAKGESVTTSILNAGFP
                     DSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDD
                     DATLISELQQMFPAADNAPADLMFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVW
                     QALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIVIPCHRVVRGDGSLSGY
                     RWGVSRKAQLLRREAENEER"
     gene            3682..4332
                     /gene="alkB"
                     /locus_tag="RH288_004373"
     CDS             3682..4332
                     /gene="alkB"
                     /locus_tag="RH288_004373"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HDV4033350.1"
                     /translation="MLDLFADGEPWQEPLAAGAVILRRFAFNAAEQLIRDINDVASQS
                     PFRQMVTPGGYTMSVAMTNCGHLGWTSHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQR
                     AATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
                     RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTTDCRYNLTFRQAGKKE"
     gene            4408..6051
                     /gene="yojI"
                     /locus_tag="RH288_004374"
     CDS             4408..6051
                     /gene="yojI"
                     /locus_tag="RH288_004374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin J25 efflux ABC transporter YojI"
                     /protein_id="HDV4033351.1"
                     /translation="MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETA
                     DTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAIT
                     IWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDA
                     QEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFSYQD
                     NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQP
                     EDYRKLFSAVFTDVWLFDQLLGPEGKPANPQLVEKWLAQLKMAHKLELSNGRIVNLKL
                     SKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA"
BASE COUNT         1461 a         1528 c         1648 g         1472 t
ORIGIN      
        1 attattattg cttgatgtta ggtgcttatt tcgccattcc gcaataatct taaaaagttc
       61 ccttgcattt acattttgaa acatctatag cgataaatga aacatcttaa aagttttagt
      121 atcatattcg tgttggatta ttctgcattt ttggggagaa tggacttgcc gactgattaa
      181 tgagggttaa tcagtatgca gtggcataaa aaagcaaata aaggcatata acagagggtt
      241 aataacatga aagttaaagt actgtccctc ctggtcccag ctctgctggt agcaggcgca
      301 gcaaacgctg ctgaagttta caacaaagac ggcaacaaat tagatctgta cggtaaagta
      361 gacggcctgc actatttctc tgacaacaag tcagaagacg gcgaccagac ctatgtacgt
      421 cttggtttca aaggcgaaac tcaggttact gaccagctga ccggttacgg ccagtgggaa
      481 tatcagatcc agggcaatac ctctgaagac aacaaagaaa actcctggac ccgtgtggca
      541 ttcgcaggtc tgaaattcca ggatgtaggt tctttcgact acggtcgtaa ctacggcgtt
      601 gtttacgatg taacttcctg gaccgacgta ctgccagaat tcggtggcga cacctacggt
      661 tctgacaact tcatgcagca gcgtggtaac ggcttcgcga cctaccgtaa caccgacttc
      721 ttcggtctgg ttgacggtct gaactttgct gttcagtacc agggcaaaaa cggtagcgta
      781 agcggcgaag gcatgaccaa caatggtcgt ggtgctctgc gtcagaatgg cgacggtgtc
      841 ggcggatcta tcacttatga ttacgaaggc ttcggtatcg gtgctgcagt ttccagctcc
      901 aaacgtactg atgatcaaaa tggtagctac accagcaatg gtgtagttcg taactacatc
      961 ggtactggcg accgtgctga aacctacact ggtggtctga aatacgacgc taacaacatc
     1021 tacctggctg ctcagtacac ccagacctac aacgcaactc gcgtaggttc cctgggttgg
     1081 gcgaacaaag cacagaactt cgaagctgtt gctcagtacc agttcgactt tggtctgcgt
     1141 ccgtccctgg cttacctgca gtctaaaggt aaaaacctgg gtgtcatcaa tggtcgtaac
     1201 tacgacgacg aagatatcct gaaatatgtt gatgttggtg cgacctacta cttcaacaaa
     1261 aacatgtcca cctacgttga ctacaaaatc aacctgctgg acgacaacca gttcactcgt
     1321 gacgctggca tcaacactga taacatcgta gctctgggtc tggtttacca gttctaatct
     1381 cgattgatat cgaacaaagg gcctgcgggc ccttttttca ttgttttcag cgtacaaaca
     1441 cagttttttg gtgtactctt gcgaccgttc gcatgaggat aatcacgtat ggaaataagc
     1501 tttacccgcg tggcactgct ggctgccgcg ctcttctttg ttggttgcga tcaaaaacca
     1561 caacccgcca aaacccacgc tactgaagtt accgttcttg aaggcaaaac catgggtacc
     1621 ttctggcgtg ccagcatccc gggcattgat gccaaacgca gtgccgaact taaagaaaag
     1681 attcagaccc agctggacgc cgacgatcag ctgctttcga cctataaaaa agattccgcg
     1741 ctgatgcgct ttaacgactc gcaaagtttg tcgccgtggc cggtaagtga agcgatggcc
     1801 gatatcgtca ccacctcgct gcgcattggc gcaaggaccg atggtgcgat ggatataacc
     1861 gtcgggccac tggtgaatct gtggggtttt ggcccggaac aacagccggt acaaatcccg
     1921 agccaggaac agattgatgc gatgaaagcc aaaaccggct tacagcacct gacggtcatt
     1981 aatcagtcgc atcagcaata tctgcaaaaa gacctgccgg atttatatgt cgatctctcc
     2041 accgtcggtg aaggttatgc ggcggatcac ctggcacgct tgatggagca ggaagggatt
     2101 tcccgctatc tggtgtcggt gggcggcgcg ctgaacagcc gtggtatgaa cggtgaaggc
     2161 cagccgtggc gggtagcgat tcaaaaacca accgataaag aaaacgcggt tcaggctgtg
     2221 gtggatatca acggtcatgg gattagcacc tctggcagct accgtaacta ttacgaactg
     2281 gacggcaaac gtctttccca tgttatcgat ccgcaaaccg ggcgtcccat cgaacacaat
     2341 ctggtatccg tgacggtgat tgctccgacg gcgctggaag ccgatgcctg ggatactggc
     2401 ttgatggtac tcgggccgga gaaagccaaa gaggttgttc gccgggaagg gctggcggtt
     2461 tatatgatca ccaaagaagg cgatagcttt aaaacctgga tgtcaccaca gtttaaaagc
     2521 ttccttgtca gcgaaaaaaa ttaaagcgca agattgttgg tttttgcgtg atggtgaccg
     2581 ggcagactaa aggctatcct taaccaggga gctgattatg aaaaaagcca catgcttaac
     2641 tgacgatcaa cgctggcaat ctgtcttagc ccgcgacccg aatgccgacg gcgaattcgt
     2701 tttcgccgtg cgtaccacag gcatcttttg ccgtccgtct tgccgcgcca gacatgcttt
     2761 gcgggaaaac gtctccttct acgcaaatgc cagtgaggca ctcgccgctg gctttcgccc
     2821 ctgcaaacgt tgtcagccag acaaagccaa tccccggcaa catcggttgg ataaaatcac
     2881 ccacgcgtgt cgactgctgg aacaggaaac gcctgtaacg ctggaagcct tagccgacca
     2941 ggtggcgatg agtccatttc atctacatcg gttgtttaaa gcgactaccg gaatgacgcc
     3001 taaagcctgg caacaggcct ggcgcgctcg ccgtttgcgc gaatcgctgg cgaaagggga
     3061 gagcgtgacg acgtctattc ttaacgccgg attccccgac agcagcagtt actaccgcaa
     3121 agccgatgaa acgctgggca tgacggctaa acaattccgt cacggtggcg aaaatctggc
     3181 ggtgcgttac gcgctggctg attgtgagct gggtcgttgc ctggtggcag aaagcgagcg
     3241 ggggatttgc gcgatattgc tgggcgatga tgacgccaca ttaatcagcg agttgcaaca
     3301 aatgtttccc gctgccgaca acgcgcctgc cgatctgatg tttcagcaac atgtgcgtga
     3361 agtgatcgcc agcctcaatc aacgcgatac gccgctgacg ttaccgctgg acattcgcgg
     3421 cactgctttt cagcaacaag tctggcaggc actgcgcacg ataccttgcg gtgaaaccgt
     3481 cagttatcag caactggcta acgccatcgg caaaccgaaa gcggtacggg ccgttgcaag
     3541 tgcctgtgcc gccaacaagc tggctatcgt tataccctgt catcgggtag tacgcggtga
     3601 tggatcgctt tcaggttacc gctggggcgt gtcgcgtaaa gcgcaactgc tgcgccgcga
     3661 agctgaaaat gaggagaggt aatgttggat ctgtttgccg atggtgaacc gtggcaagag
     3721 ccactggcgg ctggagcggt aattttacgg cgttttgctt ttaacgctgc ggagcaacta
     3781 atccgcgata ttaatgacgt tgccagccag tcgccgtttc gccagatggt cacccccggg
     3841 ggatatacca tgtcggtggc gatgaccaac tgtgggcatc tgggctggac gagccatcgg
     3901 caaggttatc tctattcgcc cattgatccg caaacaaata aaccgtggcc cgccatgcca
     3961 cagagttttc ataatttatg tcaacgtgcg gctacggcgg cgggctatcc agatttccag
     4021 ccagatgctt gtcttatcaa ccgctacgct cctggcgcga aactgtcgct gcatcaggat
     4081 aaagacgaac cggatctgcg cgcgccaatt gtttctgttt ctctgggctt acccgcgatt
     4141 tttcaatttg gcggcctgaa acgtaatgat ccgctcaaac gtttgttgtt ggaacatggc
     4201 gatgtggtgg tatggggcgg tgaatcgcgg ctgttttatc acggtattca accgttgaaa
     4261 gcggggtttc atccactcac caccgactgc cgctacaacc tgacattccg tcaggcaggt
     4321 aaaaaagaat aaaaataaga attattattg ctgtgcgcgc gaagatgttt aaactgcggg
     4381 ctgtaattca ttgtccgggt tttctgcatg gaacttcttg tacttgtctg gcggcagtat
     4441 cgctggccat ttatcagtgt gatggcgcta agcctcgcca gtgcggcatt aggcattggc
     4501 ttaattgctt ttatcaatca gcgccttatc gaaacggcgg ataccagtct gctggtgttg
     4561 ccggagtttc ttggattatt actgctgttg atggcagtca ctctcggatc gcaactggcg
     4621 ctcaccactt tggggcatca cttcgtttac cgactgcgta gtgaatttat caagcggatt
     4681 ctggataccc acgtcgagcg cattgaacaa ctcggtagcg cctcgttgct ggcgggatta
     4741 accagcgatg tgcgcaatat caccattgct tttgtgcgtc ttccggaact ggtgcagggg
     4801 atcattctca ctatcggttc cgcggcgtat ctgtggatgc tgtcgggcaa aatgttgctg
     4861 gtaacggcta tctggatggc gatcaccatc tggggtggtt ttgtactggt ggcgcgggtg
     4921 tacaaacata tggcgaccct gcgtgaaacc gaagacaagc tgtacacgga ttttcaaacc
     4981 gtactcgaag ggcgcaaaga gctgactctg aaccgggaac gcgccgagta tgtgtttaac
     5041 aacctctaca tccccgatgc gcaagagtat cgccatcata ttattcgcgc agacaccttc
     5101 catcttagcg ccgtgaactg gtcaaacatc atgatgctgg gcgctatcgg cctggtgttc
     5161 tggatggcga acagtctcgg ttgggctgat accaacgttg ctgcgaccta ttcgttgacg
     5221 ctgttattcc tgcgtacgcc gctgctttcg gcggttggcg cattgccgac gctgctgacg
     5281 gcgcaggtgg cgtttaacaa gctgaacaaa ttcgcgctcg cgcctttcaa agctgagttt
     5341 ccgcgcccgc aggcgtttcc caactggcaa acgctggagc tgcgtaacgt gacgtttagc
     5401 tatcaggata acgcgttttc cgttgggccg attaacctca ccattaaacg tggcgagctg
     5461 ctgtttctga ttggtggcaa cggtagtgga aaatcgacgc tggcgatgtt gctgacgggc
     5521 ttgtaccagc cacaaagcgg cgaaatcttg ctggatggca aacctgtcag tggcgaacaa
     5581 ccggaagatt atcgcaaact gttttcggca gtgtttaccg atgtctggct gtttgatcaa
     5641 ctgctggggc cggagggtaa acccgctaac ccgcaactgg ttgagaagtg gctggcgcag
     5701 ctgaaaatgg ctcataagct tgagttaagc aacgggcgta ttgttaacct gaagttatca
     5761 aaagggcaga aaaaacgcgt ggcgctgttg ctggcgctgg cagaagaacg cgatattatc
     5821 ctgctggatg aatgggcggc ggatcaggat ccacacttcc gtcgtgagtt ttatcaggtg
     5881 ttgctgccgc tgatgcagga gatgggtaaa actattttcg ctatcagtca tgatgatcat
     5941 tactttatcc acgccgaccg cctgctggaa atgcgcaatg ggcaacttag cgagctgacg
     6001 ggcgaagagc gcgatgccgc ttcgcgtgat gccgttgccc ggacggcata atattacgac
     6061 gctgacctgg cggactgctg ccgtcaggtc aatatgctaa aaatccctt
//
LOCUS       DAPHKZ010000198         6065 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.199, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000198 DAPHKZ010000000
VERSION     DAPHKZ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6065
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.199"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(1..865)
                     /locus_tag="RH288_004375"
                     /pseudo
     CDS             complement(1..865)
                     /locus_tag="RH288_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element ISVsa5 family transposase"
     gene            complement(900..3905)
                     /locus_tag="RH288_004376"
     CDS             complement(900..3905)
                     /locus_tag="RH288_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="HDV4033352.1"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSR
                     GDHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTR
                     REHAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILP
                     GATTLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGP
                     VTISGPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQK
                     RMAVLVAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALA
                     SACSYLLKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRV
                     RRFLPHLLNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVIN
                     KEKHITRRGYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRS
                     LGHPTDPQEAIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPD
                     SLKRLSKMISDLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMA
                     EACNIGLEPLIRSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGG
                     GEVASADGMRFVTPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDS
                     IFVLEGLLEQETGLNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDH
                     DADYGVLNDIARGQSDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLKSERPSGLT
                     QAIIEVGRINKTLYLLNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYT
                     DGQEDQLGTLGLVTNAVVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINML
                     GHYSFTLAELVTKGHLRPLKEASEAENVA"
     gene            4069..4626
                     /locus_tag="RH288_004377"
     CDS             4069..4626
                     /locus_tag="RH288_004377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDV4033353.1"
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTD
                     REGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGD
                     MGQMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTG
                     ATEIAHQLSIARSTVYKILEDERAS"
     gene            4809..5045
                     /locus_tag="RH288_004378"
                     /pseudo
     CDS             4809..5045
                     /locus_tag="RH288_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="hydrolyzes the beta-lactam bond in antibiotics such
                     as the penicillins and cephalosporins; incomplete; partial
                     in the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase LEN-27"
     gene            5062..6030
                     /locus_tag="RH288_004379"
     CDS             5062..6030
                     /locus_tag="RH288_004379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS903B family transposase"
                     /protein_id="HDV4033354.1"
                     /translation="MKDQITHLPDNADRSVAKQKFKITNWPTYNKALINRGSITFWLD
                     DEAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFSLMNVP
                     LRCPDYSCVSRRAKSVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRI
                     WRKLHLAVDSKTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRSAAADGAYDTRLCHD
                     ELRRKKISALIPPRKGAGYWPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETA
                     MYRVKQLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
BASE COUNT         1511 a         1502 c         1524 g         1528 t
ORIGIN      
        1 agccagaatg ccgcaaaact tccatgccta agcgaactgt tgagagtacg tttcgatttc
       61 tgactgtgtt agcctggaag tgcttgtccc aaccttgttt ctgagcatga acgcccgcaa
      121 gccaacatgt tagttgaagc atcagggcga ttagcagcat gatatcaaaa cgctctgagc
      181 tgctcgttcg gctatggcgt aggcctagtc cgtaggcagg acttttcaag tctcggaagg
      241 tttcttcaat ctgcattcgc ttcgaataga tattaacaag ttgtttgggt gttcgaattt
      301 caacaggtaa gttagttgct agaatccatg gctcctttgc cgacgctgag tagattttag
      361 gtgacgggtg gtgacaatga gtccgtgtcg agcgctgatt ttttcggcct ttagagcgag
      421 atttatacaa tagaatttgg catgagattg gattgctttt agtcagcctc ttatagccta
      481 aagtctttga gtgactagat gacatatcat gtaagttgct gataggtttc cagttttccg
      541 ctcctaggtc tgcatattgt acttttcctc ttactcgact taaccagtac caacccagct
      601 tctcaacgga tttataccat ggcactttaa agccagcatc actgacaatg agcggtgtgg
      661 tgttactcgg tagaatgctc gcaaggtcgg ctagaaattg gtcatgagct ttctttgaac
      721 attgctctga aagcgggaac gctttctcat aaagagtaac agaacgaccg tgtagtgcga
      781 ctgaagctcg caataccata agtcgttttt gctcacgaat atcagaccag tcaacaagta
      841 caatgggcat cgtattgccc gaacaggggg tctgacgctc agtggaacga aaactcacgt
      901 taagcaacgt tttctgcctc tgacgcctct tttaatggtc tcagatgtcc tttggtcacc
      961 agttctgcca gcgtgaagga ataatggccg agcatattga tatgtccgtg gcaaagcggg
     1021 gagaggcgtg cgatatcttc atcattcagt gtttcaccct gcgcccggag atgatccagg
     1081 gctgcctgca tataaatagt gttccataac acgacggcgt tagtgaccag ccccagtgtg
     1141 cccagttgat cttcctgacc gtcggtatat cgttttctta tctcaccttt ttgaccgtga
     1201 cagatggctc tggcaacggc atggcgactt tctccccgat taagctgggt cagaatgcgc
     1261 cggcggtaat cttcatcatc aatataatta agcagataca gcgttttgtt gatgcgcccc
     1321 acttcaatga ttgcctgagt cagtccggaa ggacgttcac ttttcagcaa tgaacggacc
     1381 agcactgaaa cctgtacttt gcccagcttc agggagccag cggtccggat catttcgtcc
     1441 cactgaagga ctatttttcg gggatctgat tgccctctgg caatatcatt cagcacgcca
     1501 tagtcggcat catggtccat tcgccagaaa accgaagcac cggcatcagc caggcgtgga
     1561 gaaaactggt atcccagcag ccagaaaagg ccaaagacaa gttcgctggc acctgctgta
     1621 tcggtcataa tttcggttgg attcagcccg gtctcctgtt ccagaagacc ttccagcaca
     1681 aagatagagt ccctcagcgt ccccggtata acgatgccat gaaagccgga atactgatcg
     1741 gacacaaagt tgtaccaggt gatccctctg ttattaccaa agtatttgcg gttcggtccg
     1801 gcattgattg ttctgactgg cgtaacaaag cgcattccat ctgcagatgc cacttctcct
     1861 ccaccccata tctgtgccag tggcagcgtt gcctgaaaat caaccagtct ggcattagcg
     1921 ctggtgatag tttcagcccg cagatagttc gcttttgtcc agttcagccg gtgtcgggtc
     1981 agtgcaggaa catttgatct gatcagtggt tccagaccga tattgcaggc ttcagccatc
     2041 agcacggcgc tgatgctgac gggcagatca tcaactctgg cactggcttc actagcatgg
     2101 aaaaactcat cagcaaatcc ggtatgggcg ttaatttcga gcagcaactc cgttaaatcc
     2161 accggaggga gtagatcact gatcattttg ctcagtcgtt tcagactgtc cggctcatca
     2221 agactggcga ggggagaaat tgtcaaccgg ggcttcgggc cagaaacatc gagttcgaca
     2281 gcctcatttt cgcaaagacg tgcagcaacc tgtctgtaac gactatcaag ctgatgaccc
     2341 agagatttta ttgcttcctg cgggtctgtc gggtgcccca aagaacgata aaccttaatc
     2401 cggtttgcct gccagtcagc accctgtagt aatcttgcac gaggatctcc ccaccggtta
     2461 ctgccggtaa cgtagacatc cctccgcctc agactatcct gcagtttact gagaaagcag
     2521 agcgtgtatc ccctgcgggt gatatgtttt tccttgttaa tcaccagccg tttccatgac
     2581 cgactgataa tttccgttgg tgcgtcgtca aaaaactgcc gccgtgagct gaactcccgg
     2641 ctgaggtagt cacaggcatt cagagtggta accccggcag gtgcggatga aaatttaacg
     2701 gtattcagca gatggggcag gaaacgacga acgcgcccgt actgctccac catttcttca
     2761 tgaaaattat cgtctgaggg ccgggcaatt tcacggacaa gcgtgatgat ttcagccagc
     2821 ttttgccttg ggatgtagct gaacacctca gcacgaatcg attcgtccgg tgtttcttct
     2881 ttcagcaggt acgaacatgc gctggcgagc gccaatgcag atttatccag atccttcagc
     2941 gagcggagcc gttttttctg cccaatcttt ctggcgtcac ggatgataac ggccagcatg
     3001 gcgtccagaa cgtccaatgc atcatccagc gccagcgttt cccatgcaag gacaaaggca
     3061 accagaaccg ccatcctttt ctgcggtgac atcctggcaa tattgaacac cgaagtcata
     3121 ccagcataac gtgcgagatt tttcaggcgc acagccggga gtgtactcag gttttcagca
     3181 tgcaggccaa aatcgttcag agttttccag cgttcaattg cttcattaaa cgccggacca
     3241 ctgatggtca cagggccctt tttcagtgat tccagtaaag acaggcggct gcaatcagtt
     3301 ggccccagca gcatctccag ctgtgaacgc tgttcggctg acggtatcag tgccagtttg
     3361 ttccacaggc gcaacgtcgc cttttccctt acctctgaaa tcaaccgggt cagcgtagtg
     3421 gctccgggga gaataatacg atgttgcata agccaccctg tcgccagatc gaaaagcagg
     3481 ccaggacgtt cgttgcttat ccagctccgg gtatataaaa gacgggtaag gcgaaatgtc
     3541 cagggccagg caaattcacg atactgatag tgctgacgta tcagcgctgc atgctcacgg
     3601 cgggtatttt ccctctgacc gtattctgca agaacggtga tatcacgaat cccgagctgt
     3661 ctggcggtaa aatgccggac gccggaagga atatgattca tatcggtgag gaaggtgccc
     3721 agaaaacgga cacatccaat ttgcagggca atgcccagac ggttgtgatc acctctgctt
     3781 tttccgataa attccttgtc tgcttcatca aggtgaaaat atcgtgccag ctgaagctca
     3841 tccggttcac cggtgaatct gccatagctt tcagtctgct cagtggtcag aaagtcaacg
     3901 ggcatatcgg cctccctgcc tgacgggcat ttagtaacat ttttccaacc gtacgaaatg
     3961 ttataaatta tcggacatcg taaaactgtt acattaatat gtctattaaa tcgtaaattt
     4021 gtaataatag acatgagttg tccgatattc gatttaaggt acatttttat gcgacttttt
     4081 ggttacgctc gggtctcaac cagtcagcag tctcttgatc ttcaggtcag agcactcaaa
     4141 gacgcaggtg tgaaagcaaa ccgtatattt accgataagg catccggcag ttcaacagac
     4201 cgggaagggc tggatttgct gaggatgaag gtggaggaag gtgatgtcat tctggttaag
     4261 aagctcgacc gtcttggccg cgacactgcc gatatgatcc aactgataaa ggaatttgac
     4321 gctcagggcg tggcagtccg gttcattgat gacgggatca gtaccgacgg tgatatgggg
     4381 caaatggtgg tcaccatcct gtcggctgtg gcacaggctg aacgccggag gatcctagaa
     4441 cgcacgaatg agggccgaca ggaagcaaag ctgaaaggaa tcaaatttgg ccgcaggcgt
     4501 accgtggaca ggaacgtcgt gctgacgctt catcagaagg gcactggtgc aacggaaatt
     4561 gctcatcagc tcagtattgc ccgctccacg gtttataaaa ttcttgaaga cgaaagggcc
     4621 tcgtgatacg cctattttta taggttaatg tcatgataat aatggtttct tagacgtcag
     4681 gtggcacttt tcggggaaat gtgcgcggaa cccctatttg tttatttttc taaatacatt
     4741 caaatatgta tccgctcatg agacaataac cctggtaaat gcttcaataa tattgaaaaa
     4801 ggaagagtat gagtattcaa cattttcgtg tcgcccttat tccctttttt gcggcatttt
     4861 gccttcctgt ttttgctcac ccagaaacgc tggtgaaagt aaaagatgct gaagatcagt
     4921 tgggtgcacg agtgggttac atcgaactgg atctcaacag cggtaagatc cttgagagtt
     4981 ttcgccccga agaacgtttt ccaatgatga gcacttttaa agttctgctg gctttgttga
     5041 ataaatcgaa cttttgctga gttgaaggat cagatcacgc atcttcccga caacgcagac
     5101 cgttccgtgg caaagcaaaa gttcaaaatc accaactggc ccacctacaa taaagccctc
     5161 atcaaccgtg gctccataac tttctggctg gatgatgaag ctattcaggc ctggtatgag
     5221 tcagcaacac cttcttcacg aggcagacct cagcgctatt ctgaccttgc catcacgact
     5281 gtgctggtca ttaaacgcgt attcaggctg accctgcgcg ctgcgcaggg ctttattgat
     5341 tccatttttt ctctgatgaa cgttccgcta cgctgcccgg attacagctg tgtcagcagg
     5401 cgggcaaagt cggttaatgt cagtttcaaa acgcccaccc ggggtgaaat cgcacacctg
     5461 gtaattgatt ccaccgggct gaaggtcttc ggtgaaggcg agtggaaagt caaaaagcat
     5521 ggccaggaac gccgccgtat ctggcgtaag ctgcatctcg ccgttgacag taaaacacat
     5581 gaaatcatct gcgctgacct gtcgctgaac aacgttacgg actcagaggc cttccccggg
     5641 ttaatccggc aaacccaccg gaaaatcagg tcagccgccg ccgatggcgc ttacgatacc
     5701 cggctatgtc acgatgaact gcggcgtaag aaaatcagcg cgcttatccc tccccgaaaa
     5761 ggtgcgggtt actggcccgg tgaatatgca gaccgtaacc gtgcagtggc taatcagcga
     5821 atgaccggga gtaatgcgcg gtggaaatgg acaacagatt acaaccgtcg ctcgatagcg
     5881 gaaacggcga tgtaccgggt aaaacagctg ttcgggggtt cactgacgct gcgtgactac
     5941 gatggtcagg ttgcggaggc tatggccctg gtacgagcgc tgaacaaaat gacgaaagca
     6001 ggtatgcctg aaagcgtgcg tattgcctga aaacacaacc cgctacgggg gagacttacc
     6061 cgaaa
//
LOCUS       DAPHKZ010000199         6027 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.200, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000199 DAPHKZ010000000
VERSION     DAPHKZ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6027
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.200"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            129..1262
                     /gene="ompN"
                     /locus_tag="RH288_004380"
     CDS             129..1262
                     /gene="ompN"
                     /locus_tag="RH288_004380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpN"
                     /protein_id="HDV4033355.1"
                     /translation="MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGL
                     KFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFF
                     GLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAY
                     TSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADIGATY
                     YFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF"
     gene            1403..1837
                     /gene="uspF"
                     /locus_tag="RH288_004381"
     CDS             1403..1837
                     /gene="uspF"
                     /locus_tag="RH288_004381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415894.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HDV4033356.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEEEAKIDDAEVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILEL
                     AKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
     gene            2014..2949
                     /gene="ttcA"
                     /locus_tag="RH288_004382"
     CDS             2014..2949
                     /gene="ttcA"
                     /locus_tag="RH288_004382"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDV4033357.1"
                     /translation="MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGD
                     LAFDREEIPLQPACWQPEEDENQLDELRLNVVEVK"
     gene            complement(3078..4451)
                     /gene="dbpA"
                     /locus_tag="RH288_004383"
     CDS             complement(3078..4451)
                     /gene="dbpA"
                     /locus_tag="RH288_004383"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HDV4033358.1"
                     /translation="MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVR
                     VQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
                     ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
                     MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQ
                     QFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLE
                     QRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTAR
                     AGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKK
                     AKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
                     CRVRLLK"
     gene            complement(4929..5912)
                     /gene="zntB"
                     /locus_tag="RH288_004384"
     CDS             complement(4929..5912)
                     /gene="zntB"
                     /locus_tag="RH288_004384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HDV4033359.1"
                     /translation="MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLH
                     LNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPD
                     QLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
                     FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMV
                     FLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL"
BASE COUNT         1597 a         1514 c         1424 g         1492 t
ORIGIN      
        1 atttgattaa ggttttactt aaggcgtaac aaatgatatt tatcggctaa ctgaacttct
       61 cctttaggat gttttcactc cccgaaatgg ggataaaagg caaataaaat aactaaagga
      121 tttattcaat gaaaagcaaa gtactggcac ttttaattcc tgccctgctc gccgcaggtg
      181 ctgcacatgc agccgaagtt tataataaag acggcaacaa attagatctg tatggcaaag
      241 ttgatggcct gcattatttt tctgataatt cagcgaaaga tggcgaccag agctatgcgc
      301 gtctgggttt taaaggcgaa acccaaatta acgatcaact cactggctac ggtcaatggg
      361 aatacaatat tcaggcaaac aacactgaat cttcaaaaaa ccagtcatgg acccgtctgg
      421 catttgccgg gctgaaattt gcagattacg gttctttcga ttacggacgt aattatggcg
      481 taatgtacga catcgaaggc tggaccgata tgctgcctga atttggcggt gactcttata
      541 ccaatgcaga caactttatg actggtcgag ccaatggcgt cgcgacttat cgtaatactg
      601 atttcttcgg tctggtaaat ggtctgaact tcgcggtgca gtatcaaggt aacaacgaag
      661 gagccagtaa tggtcaggaa ggcaccaaca acggacgtga tgttcgccat gaaaacggtg
      721 acggctgggg tctttccaca acatatgatt taggcatggg ctttagcgct ggtgcggcat
      781 acacctcttc tgaccgcacc aatgaccagg ttaaccatac tgcggcgggt ggtgataaag
      841 cagacgcgtg gactgctggg ctaaaatacg atgctaacaa tatttacctg gcaaccatgt
      901 attcagaaac gcgtaatatg accccgtttg gcgacagcga ttatgctgtg gcaaacaaaa
      961 cccagaattt tgaagtcact gcacagtacc agtttgattt tggtctgcgt ccggcagtct
     1021 ctttcctgat gtctaaaggc cgtgacctgc acgctgcggg tggtgcagac aacccggcag
     1081 gtgttgatga taaagatctg gttaaatacg ccgatattgg cgcgacttac tatttcaata
     1141 aaaacatgtc cacctacgtt gactataaaa tcaacctgtt ggatgaagat gacagcttct
     1201 acgctgccaa tggcatctct accgatgata ttgtcgcttt aggtctggtt tatcagttct
     1261 aaatcctcct gcccgctgtt atggcgggct ttttctgctt attcttcctc ctttgatcta
     1321 aattaaaaat gtgaactccg tcattacaca aaaagtgtca tctggcgtta cactttatgc
     1381 ggatactaaa acaggaggtt ttatgaacag aacgattctt gtccctatcg atatttccga
     1441 ttcagaatta actcaacgcg tgattagcca cgttgaggaa gaggcaaaga ttgatgatgc
     1501 agaggttcat ttcctgacgg taataccttc actgccctac tatgcctctc tgggtttagc
     1561 gtattccgca gaattaccgg caatggatga cctgaaagcg gaagccaaat cgcaactgga
     1621 agagatcatt aaaaaattta aactgccaac cgacagagtg catgtccatg ttgaggaagg
     1681 ctcgcccaaa gaccgcattc tggaattggc gaagaagatc cccgctcata tgatcatcat
     1741 tgcttcccat cgaccggata tcaccactta tctgctcggt tccaacgccg cagctgtagt
     1801 gcgtcacgca gagtgctccg tgctggttgt gcgctgacac taacgcccgc acattgctgc
     1861 gggctttttg attcatttcg caaatgtgct gacattttcc cctctaatcc gtaccataca
     1921 cgccacagtt ttttatatca gatttcttat gctgggcgtt ccggcatgac gcatactctt
     1981 ctgatgccat ataacgaatt gagtcgcttt taaatgtcgc aaaatcaaga aattagtaag
     2041 aaagaacaat acaacctgaa caaattacaa aaacgtctgc gtcgtaacgt gggcgaagcc
     2101 attgctgact tcaatatgat tgaagaaggc gatcgcatca tggtttgcct ctccgggggt
     2161 aaagacagct ataccatgct ggagattctg cgcaatttgc agcaaagcgc gccaatcaat
     2221 ttttcgctgg tggctgttaa cctcgatcaa aagcaaccgg gcttcccgga acacgttctg
     2281 cccgagtatc ttgaaaagct gggcgttgag tacaagattg ttgaagagaa tacttacggt
     2341 atcgtgaaag agaagattcc agagggcaaa accacttgct cactgtgttc tcgccttcgt
     2401 cgcggtatcc tttatcgtac cgcaacggaa ctgggggcga cgaagatcgc gttgggtcac
     2461 catcgtgacg atatcctgca aacgttgttc ttaaatatgt tctacggcgg taagatgaaa
     2521 ggtatgcctc cgaaactgat gagcgatgat ggcaaacata tcgttattcg tccgctggcc
     2581 tactgccgcg agaaagatat tcagcgattt gccgatgcaa aagcgttccc gattattccg
     2641 tgcaacctgt gcggttcaca gcctaacctg caacgtcagg tgattgctga catgttgcgt
     2701 gactgggata aacgttatcc agggcgtatc gagacgatgt tcagcgcgat gcagaatgtg
     2761 gtgccgtcgc atctgtgcga taccaacctg ttcgatttca aaggcatcac ccacggttct
     2821 gaagtggtta acgggggtga tctggcgttt gatcgcgaag agatcccact acaaccggcg
     2881 tgctggcagc cagaagaaga tgaaaatcag ttggatgagt tacggctgaa tgtggttgaa
     2941 gtgaaataac caggatagcg cccgatgcgc aagcgtatcg ggctactctt atggaggccg
     3001 gataagacgc ggccagcgtc gcatccggca atcccgaata agatgtttac tcttgcaccc
     3061 ggcaattcaa catttcatta ttttaataac cgcacccggc acgtttttcc tttaatcttc
     3121 ccgccctgta actgtttcca tgctttatga gcaacagcct gacggaccgc gacatagaca
     3181 tgcgccggat gcacggcgat tttgccaata tctgcgccat caagcccgat atctcctgtc
     3241 agtgcaccta atacatcacc cgggcgcatt ttggcttttt tcccgccatc gatacacaac
     3301 gttgccattt ctgcttccag cgtcgcaatg gaactattag ctggcggcgt ttgccagtta
     3361 agttttatct gcaacatgtc agaaatgata ttggcccgct gtgcttcttc cggagcacag
     3421 aaactgatcg ccagaccgct atttcctgca cgagctgtac gaccgatgcg atgtacatga
     3481 acttcagggt cccacgccag ctcaaagttc accaccagct caagcgattt aatatccaga
     3541 ccacgcgcag caacatcagt cgcgaccagt acacgggcgc taccgttagc aaaacgtacc
     3601 agggtctgat cgcgatcgcg ttgctccaaa tcgccgtgta atgacaatgc actttgccct
     3661 acttcattca gcgcgtcgca gacagcctgg caatcttttt tggtattgca aaacaccacg
     3721 caagaggatg gctgatgcaa gcttaataac cgttgcaaca gaggaatttt gcctttgctg
     3781 gatgtctcat aaaattgttg ttcaatgggt ggcaaagcat ctgttgagtc aatttcaatc
     3841 gccaaaggat cgcgttgcac tcgtccgctg attgcagcga tggcttccgg ccaggttgcc
     3901 gaaaacagaa gcgtctgtcg agatgcaggc gcaaaacgga tgacatcatc aatggcatcg
     3961 ctaaatccca tatccagcat gcggtcggcc tcatccatca ccagcgtatt caacgcatcc
     4021 agtgataccg tgcctttttg caggtgatcc agcaaacgcc ccggcgttgc cacgataata
     4081 tgcggcgcat gttgcaacga atcacgctgc ataccgaacg gttgaccacc gcacaacgtc
     4141 aaaattttgg tatttggcag aaaacgcgcc agccgacgca attcacctgc cacctgatcc
     4201 gccagttcac gcgtaggaca cagcactaaa gcctgggttt gaaatagcga cgcatcaatt
     4261 tgctgtaaca agccgaggcc aaaagccgcc gttttgccgc tgccggtttt cgcctgcacg
     4321 cgaacatctt ttccggcaag gatcgccgga agcgcggcgg cctgcaccgg cgtcatggtt
     4381 aaataaccca actcattaag gttcgtgagt tgggcgggag gcaaaacatt cagggtagaa
     4441 aaagcggtca caatctattc tcgtggtcat cgacgcaaag ttagcaggcg cgtatcctcg
     4501 cagatctacg ctcacgatgc gacaatttaa tcggttcttc atcgggtggt gggtcaggca
     4561 tgggttgcgg gcgagggatc ggatcgggca ctggaacagg atcgccagga atcggttcag
     4621 ggacaggaat ttgcaaataa ataagtgtcg tcatatttcc ctctggtcat tgggtggact
     4681 cttaaagggt agacgctgat aaataacagg caaaaaaaag ccgactcatc aaagtcggcg
     4741 tcgtacgaat caattgtgct atgcagtaat tcaaaaaagg aagtaagaca atatggagcg
     4801 caacgcccat cgcttgacgt tgcattcacc tgcaagagag atattgccct gaatgggtag
     4861 agagtttatt gacttcgctc aaactttgcg gcgtttttgt atacagacag ccggaaaaat
     4921 tgcttttgtt acaaccattt actacgatgc aaccataaag caacaccacc aataagaaca
     4981 actaacagaa tacaaaaaat tgaaaatccg aattgccacc cgccgccagg gatcccacca
     5041 aggttgacgc caaataaccc ggtcagaaag gtactgggta aaaagaccat tgccatcaac
     5101 gacattgtat aggtacgacg agctaaattt tcctgcatca cctgagcgat ttcatccgcc
     5161 atcacgccag tccgtgctat acaggcgtcg atttcgtcaa ggccgcgccc aaggcgatcg
     5221 gcaatatcct gcatccgacg gcgttggtca tcgctcatcc acggcaaacg ttcactggca
     5281 agacgagcat aaacatcacg ttgcggtgcc atatagcgac gcatcacaat taattgtttg
     5341 cgcagcagag ccaggaatcc acgcggtgga atttgctgat caaggagatt atcttcaagg
     5401 tcgataattt tatcgtgcag ctgctcgata aattcactgg aatgatcggt caacgcatcg
     5461 cacacatcca ccagccatcc cccgcaatcg gtcggacccg tgccctcttc cagatcgctc
     5521 accacatcgt ccagcgccag cactttgcgt tgtcgggtcg aaacaattaa ccgcccgtcc
     5581 atatatacac gcatggcgac cagttgatcg gggcgttcat cggtgctgcc gtttatacag
     5641 cgcaatgtaa tcagcgtgcc ttcaccgaga cggctgactc ggggacgcgt gctctcgccc
     5701 gccagcgcat cacgtacgtt attgggaagc agcggtgttg tcgccagcca ttgggcgcta
     5761 tcatggtgta cataattaag gtggagccaa cagggatgcg cttcatcaat cacatctgta
     5821 ttttccagcg gtttaacgcc gcctctacca tccagcatcc aggcaaatac tgcatccggg
     5881 acattaacgt ccgatccctt aatcgcttcc acagtgcctc catcatcaac gcattatttt
     5941 gtagtctagc cttctggccc tgttacgcaa catctcatca ccccattacc ctgaaatgat
     6001 taataaaatt ctgtctaaat tgaatac
//
LOCUS       DAPHKZ010000200         5886 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.201, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000200 DAPHKZ010000000
VERSION     DAPHKZ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5886
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.201"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1055
                     /locus_tag="RH288_004385"
     CDS             <1..1055
                     /locus_tag="RH288_004385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HDV4033360.1"
                     /translation="KRNLLSSAIIVAIMSLGLTGCDDKKAETETLPPANSQPAAPAPE
                     AKPTEAPVAKAEAKPETPAQPVVDEQAVFDEKMDVYIKCYNKLQIPVQRSLARYADWL
                     KDFKQGPTGEERTVYGIYGISESNLAECEKGVKSAVALTPALQPIDGVAVSYIDAAVA
                     LGNTINEMDKYYTQENYKDDAFAKGKTLHQTFLKNLEAFEPVAESYHAAIQEINDKRQ
                     LAELKNIEEREGKTFHYYSLAVMISAKQINNLISQDKFDAEAAMKKVSELETLVAQAK
                     EADKGGMNFSFINSAGQYQLEAKKYVRRIRDKVPYSDWDKEQLQDANSSWMVEDSFPR
                     ALREYNEMVDNYNSLR"
     gene            complement(1105..2853)
                     /locus_tag="RH288_004386"
     CDS             complement(1105..2853)
                     /locus_tag="RH288_004386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative frv operon regulatory protein"
                     /protein_id="HDV4033361.1"
                     /translation="MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFT
                     LNGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALN
                     LPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
                     GITRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIV
                     EHSGLFLGDNAVRTLTGLIEKQHQQAQVISADNVQGLLQRVPGIASLNIIDAQLVENI
                     TGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLREQLDIPLFDSDLIG
                     LYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLHCRVIIARSLSELVAIREE
                     IEPLLIINNSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGS
                     FHYSNVRGESWQHITRQICAQLVAQHHITADEAQRIIAREGEGENLIVNRLAIPHCWS
                     EQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASVLCQHPAEVI
                     AGLTGYEAFMELLHKG"
     gene            complement(2853..3923)
                     /locus_tag="RH288_004387"
     CDS             complement(2853..3923)
                     /locus_tag="RH288_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDV4033362.1"
                     /translation="MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGS
                     FVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRFTTIGGWWNQSMLNHRVTIRTHK
                     GVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEVEKRGVEIGNFISPEAN
                     FACWGEDKVVGKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEH
                     IKPDVVIVLDTAVAGDVPGIDNIKYPLKLGQGPGLMLFDKRYFPNQKLVAALKSCAAH
                     NDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSGMISKADYEALLTLI
                     RGFLTTLTAEKVNAFSQFRQVD"
     gene            complement(3913..5364)
                     /locus_tag="RH288_004388"
     CDS             complement(3913..5364)
                     /locus_tag="RH288_004388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIBC"
                     /protein_id="HDV4033363.1"
                     /translation="MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQG
                     SSGVENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISQALKNIDQIFSE
                     LPTNSQLFAADSGVKLGKQEVQSGSVMSHLMAGVSAALPFVIGGGILVALANMLVQFG
                     LPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLAND
                     KALLGTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVL
                     TYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSL
                     LEKHIYDWYAIVGVVALMPPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAI
                     PYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLA
                     IGLALNISFIIVLKGLWLRRKAKAAQQELVHEH"
     gene            complement(5375..5821)
                     /locus_tag="RH288_004389"
     CDS             complement(5375..5821)
                     /locus_tag="RH288_004389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDV4033364.1"
                     /translation="MAALTASCIDLNIQGNGAYSVLKQLATIALQNGFITDSHQFLQT
                     LLLREKMHSTGFGSGVAVPHGKSACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGV
                     PQSGEEDQVKIIGTLCRKIIHKEFIHQLQQGDTDQVLALLNQTLSS"
BASE COUNT         1521 a         1521 c         1493 g         1351 t
ORIGIN      
        1 tgaaaaggaa tttattatct tccgctatta tagtcgccat catgtccctc ggtctgacgg
       61 gttgtgatga taaaaaagcc gaaacagaaa cgctcccgcc tgccaatagt caacctgccg
      121 caccagctcc tgaagcgaaa cctactgaag ctcccgttgc aaaagcagaa gctaaacctg
      181 aaacacctgc gcaaccggtg gtcgatgaac aagcggtttt cgacgaaaaa atggatgtct
      241 atatcaagtg ctacaacaag ttacagatcc cggtacagcg cagtctggcg cgttatgctg
      301 actggctgaa agattttaaa caggggccta ccggtgaaga gcgtactgtt tatggcatct
      361 acggcattag tgaatccaac ctcgctgagt gtgaaaaagg cgtaaaaagt gctgtggcgt
      421 taacgcctgc gctgcaacca attgatggcg tggcggtgag ttatatcgat gctgccgtgg
      481 cgttgggtaa taccattaac gaaatggata aatattacac ccaggaaaat tataaagacg
      541 atgcgtttgc gaaagggaaa acgctgcacc agacattctt aaaaaatctg gaagcctttg
      601 aacctgtagc cgaatcttat catgcggcga ttcaggaaat taatgataag cgtcagcttg
      661 cggaactgaa aaatattgaa gaaagagaag ggaaaacatt ccactactac tctctggcag
      721 tcatgatttc agcgaaacaa attaataacc tgatatcgca agataagttt gatgcagaag
      781 cggcaatgaa gaaagtgtct gaactggaaa cgctggtggc gcaggccaaa gaagcggata
      841 aaggcggcat gaatttctcg tttattaatt cggcaggcca gtatcaactc gaggctaaaa
      901 aatacgttcg ccgcatcaga gataaagtcc cgtactctga ctgggataaa gagcaacttc
      961 aggacgcaaa ctcaagctgg atggtcgaag actctttccc gagagcatta cgcgagtaca
     1021 acgaaatggt tgataactat aatagcctgc gttaaacgtt tttgatgata aatgcagtgt
     1081 cggatgcggc gcatccgaca cagttcaccc cttgtgaagt aactccataa atgcctcata
     1141 tcctgttaac ccggcaataa cctctgccgg atgctgacac aatacgcttg ccagatagct
     1201 gaatattttc aactcgtgac gcgcatcggc ggcggcgcag gcgatcaaga catggttaat
     1261 gacttcgtta ttcacctcaa ctggttgggc gagggtaata aaaaatccac gaaaacgtcg
     1321 ctcctgttcg ctccagcaat gtgggatggc gaggcgatta acaatcaggt tttcaccttc
     1381 gccttcgcgg gcgatgatcc gttgcgcttc atcggcggta atatggtgtt gtgccactaa
     1441 ttgcgcacaa atttgccggg taatatgttg ccagctttca ccgcgtacat tcgaataatg
     1501 aaaacttccg ggggcagaga aaaaacgctc cggttgctgg cgaataaatg ccgtcgccag
     1561 aaaatgtttt atttgttcga taccggcagc cgtaatgata ttttttacgg tgatgtaatt
     1621 attgaccgcg tcatccagta aataatggct gttgttaatg atcaataacg gctcaatctc
     1681 ttcgcgaatg gcaacaagtt cgcttaagct acgggcaata atcacccgac aatgtaaaac
     1741 atcgcgctca atggcgagct gattaatggt ggcaatcgcg ttctggtccg agagcaaaat
     1801 gatcggctgg cgttcgtttt gatgccgctc cagcgcacag gcaaaataca aaccgatcag
     1861 atcgctgtcg aaaaggggaa tatcgagctg ttcacgcagt agcgtaataa agtgcagact
     1921 catatcaaag gccgcaggcc aggcggcttt caggttattc atgctgctct ggcggtgctc
     1981 agcaatccac actggtgcgg caaggcaacg taataaatgc ccggtaatat tctcaaccag
     2041 ctgcgcatca ataatattca atgacgcgat gcccggcacc ctttgcagca acccctgcac
     2101 attatcggct gaaattacct gcgcttgctg atgctgtttc tctatcaaac ccgtcagggt
     2161 tcttacagcg ttatcaccaa gaaacagacc gctatgttca acgatttgtt ttatctcgtc
     2221 accgggatat tgcggccact catcggtcag ttgattacgc agggcgtaaa tcgccagaat
     2281 caggctggag agataatcac cctgcatgag cggccagcgg tgttggttgt cgcaggccgt
     2341 ggataaatgc tgaaggttgt ctcgtgttat gcccgccagc ggaattaaaa acggatcttt
     2401 gcgcagcaag ttcgccagca agataacgcg tttctcttct gtctcatcaa tgaaatggcc
     2461 caaaccaggg cggctggcca ggcaacaagt gcgttcataa cgctgtttta accggggcag
     2521 acgctctgct acccacgttt ctggcaaatt aagcgccgag gcgagttgcg cacggggagt
     2581 gaaagtattc agtaataaca gcgccagcag ccgatcgtcg ttatcgtgct tttgcagcaa
     2641 ctgaaaaaag ctgcggcgct cgaagatttc cagctgatag cccgcactgc cactggcgaa
     2701 aatgcgggct ttgccgttaa gggtgaagtt gagatagtca atatcacgca ggatggtcct
     2761 gcctgaaacg ccagtctgtt gcgccagctc gccaggcgtg cgcggctgtt gctccagcag
     2821 atcgacaatc tttaactggc gttcgtttag cattaatcca cctgacggaa ctggctaaac
     2881 gcgttgactt tctccgcagt taaggtcgtc agaaaacccc gtatcagcgt gagcagagct
     2941 tcgtaatcgg cttttgaaat cataccgctg ttggcgtgca gataacgagt tggcagacac
     3001 agcgcgacaa ccggacgccc gccgcccatc acgttgtagc gcccgccatc cgtcgcaccg
     3061 gttttcatgg tggaaaattg cagcggtaaa tcgttatgtg cggcacagct ttttaacgct
     3121 gctaccagtt tctggttggg gaagtagcgc ttgtcaaaca gcatcagccc cggcccctgg
     3181 cccagtttca gcgggtattt aatgttatca atgcccggaa catcgcccgc tacggcggta
     3241 tccaacacga tcacgacgtc cggtttaatg tgttccgccg aggtttgcgc cccgcgtagc
     3301 ccaacttctt cttccacact gccaacgcca tacagcgtaa tttcgggatt attcaccgtc
     3361 tgcaatagtt cagccatcat tgcgcagccg atgcggttat ccaacgcctt gccgaccact
     3421 ttatcttcgc cccagcaggc aaaattggct tccgggctaa taaaattacc aatttccacg
     3481 ccgcgctttt ccacctcttc gcgactgttc gcgccaatat caatgaacat ctcatcaaat
     3541 gacagcggtt gttgcttttg cttttccgtt aacgcatgag gcgcgacgga accaatcaca
     3601 ccagggattt tcactccctt gtgtgtgcgt atggttaccc ggtggttgag catcgactga
     3661 ttccaccagc cgccaatggt ggtaaaacgc agaaaaccgc tctcgtcgat gtgggtgacc
     3721 ataaagccga cttcatccat atgtccgaca acggcaactt ttggaccttt attcccctta
     3781 cgggcaacaa agctgcccag accatcgaag gtgatttcat tcacgcaagg ttccagcgtg
     3841 tttatcagaa tgtcgcgaac ttcctgttca tcgccgctga cggcgctggc ttcgcacaac
     3901 tgttgcagta actcaatgtt catggacaag ctcctgttgc gcggctttcg ctttgcggcg
     3961 taaccacaat cctttcagga cgataatgaa tgaaatgttc agcgcgaggc caatcgccag
     4021 caccagataa aacgaaccca ccggcgacat caggccgatc agcgggtcaa agatacccaa
     4081 accaggtgcc agacgtttga ttccgaaagc gatcaccagc acgccggtaa tgccgcccgc
     4141 cagcgtattg gcggtaatca tcggcaacgg agctgccaga gcgtaaggaa tagccggttc
     4201 ggttgcgact gtggcaccga ccacaatggc actactggca gcctcttttt cctgtcgggt
     4261 aaacagtttg ggcgcaatga acgtcgcaag acccgccgcg acgggcggca tcagcgcgac
     4321 aacgccgacg atggcgtacc agtcataaat gtgtttttcc agcagtgaga agcagaagaa
     4381 ccaggcggtt ttattgatgg ggccgcccat atcgaacgcc agcatcgcac cgaccagaaa
     4441 cgctgccgca aacttcattg atggaggaat ggtattcagg aagtggagca gcccgcccat
     4501 gaggtcggac atcaccggcc cgataacgta gtaagtgagc acgccgaaaa ccagcagagt
     4561 aacgaacggg atcagcattg aaccgagcag cggttgtaat gctttgccaa ggcgcacttt
     4621 gcggaaccag aagacgaaat agccaatcgc cagccccagc accaccgcgc cgaggaatcc
     4681 cgcacccgac tgggtgccga gcagcgcttt gtcgttcgcc agatagcaaa ccagaaacgc
     4741 cggagcgaaa gccggtttat cggcaatcga cgaggcaata taagcgccca tgatggggat
     4801 cataaaggtg aagccaaggt aaccgatgga ttcaactacc caggtaaacg acggcgcgcc
     4861 tttcgacata tcggtatacg gcaaaccgaa ctgcaccagc atgttggcaa gcgccaccag
     4921 gataccaccg ccgatgacaa acggcagcgc cgcagagacg cccgccatca ggtggctcat
     4981 cacgctaccg ctttgcactt cctgtttgcc aagcttcacg ccgctatctg cggcaaaaag
     5041 ctgcgagttt gtcggtaatt cgctgaaaat ctggtcgata tttttcaacg cctgggagat
     5101 ggcaatctca taaactttct tcccggcaaa ccgcgcgcga tcatcaccgc tcaggccacg
     5161 cccggtagcg agaatgacgt aatcggcagc ggcaatctct tcgctggata agcggttttc
     5221 aacgccactg gacccttgag tttccacttt tatggtatga ccgagagaac gggctttctg
     5281 ttccagggct tccgccacca tgtaggtgtg agcgatcccg gcggggcagt tggtgatcgc
     5341 gacaatacgt aaggatgact ccatcgccac ttccttatga gctgagggtt tgatttaaca
     5401 aggcaagcac ctggtcggta tcgccctgtt gcagttgatg aataaattcc ttgtgaataa
     5461 ttttgcgaca cagtgtgccg atgattttga cctgatcctc ttcgccgctt tgcggcacgc
     5521 cgaggcagat ccagcaattg acgtcttcgc catcgctggc tttccagtca atagcctgcg
     5581 ctttgcgggc gaataatacg aacggttgtt taacgcaggc gcttttaccg tgcggcacgg
     5641 cgacaccgga accaaatcca gtagagtgca ttttttcgcg cagcagcagg gtttgcagga
     5701 actggtgtga gtcggtgata aaaccgtttt gtaacgctat tgtcgccaac tgcttcagaa
     5761 cggaataagc gccattgccc tgaatattca ggtcaataca gcttgcagta agagctgcca
     5821 ttaatcggac tccataaaat atattttaat caattgtaat ggtggagcga ttaagtgatg
     5881 agaggc
//
LOCUS       DAPHKZ010000201         5764 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.202, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000201 DAPHKZ010000000
VERSION     DAPHKZ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5764
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.202"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(68..400)
                     /locus_tag="RH288_004390"
     CDS             complement(68..400)
                     /locus_tag="RH288_004390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein FlxA"
                     /protein_id="HDV4033365.1"
                     /translation="MSVTIQGNTSTVISNNSAPEGTSEIAKITRQIQVLTEKLGKISS
                     EEGMTTQQKKEMAALVQKQIESLWAQLEQLLRQQAEKKNEDATVQPDKKEEKKDDTNT
                     AGTIDIYV"
     gene            complement(603..908)
                     /locus_tag="RH288_004391"
     CDS             complement(603..908)
                     /locus_tag="RH288_004391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033366.1"
                     /translation="MSLQVSHYNMLRASHEGSQKVVVRTVITVRFVPGAAIAKSILYC
                     AGQLVFKESGHHLTGTDTIYFVTVRLHMHNSTYSSIFCFSMSVLLSRRRVSGDLTCR"
     gene            933..1172
                     /gene="relB"
                     /locus_tag="RH288_004392"
     CDS             933..1172
                     /gene="relB"
                     /locus_tag="RH288_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin RelB"
                     /protein_id="HDV4033367.1"
                     /translation="MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERL
                     PFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL"
     gene            1172..1459
                     /gene="relE"
                     /locus_tag="RH288_004393"
     CDS             1172..1459
                     /gene="relE"
                     /locus_tag="RH288_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     RelE"
                     /protein_id="HDV4033368.1"
                     /translation="MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKL
                     RGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKRIL"
     gene            1531..1686
                     /gene="hokD"
                     /locus_tag="RH288_004394"
     CDS             1531..1686
                     /gene="hokD"
                     /locus_tag="RH288_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HDV4033369.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVF
                     TAYEPEE"
     gene            1903..2154
                     /locus_tag="RH288_004395"
     CDS             1903..2154
                     /locus_tag="RH288_004395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033370.1"
                     /translation="MMNIEELRKIFCEDGLYAVCVENGNLVSHYRIMCLRKNGAALIN
                     FVDARVTDGFILREGEFVTSLQALKEIGIKAGFSAFSGE"
     gene            2221..2499
                     /locus_tag="RH288_004396"
     CDS             2221..2499
                     /locus_tag="RH288_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033371.1"
                     /translation="MARNAKYYNSDNSPVLACTHGRYSHAFKSEWFQHPPCTAEQAEW
                     LIHSYRRRGFEVKKALSLDYRHWIISVRLPYSERPPRAPRTFQQRIWR"
     gene            2501..3549
                     /locus_tag="RH288_004397"
                     /pseudo
     CDS             2501..3549
                     /locus_tag="RH288_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416078.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
     gene            3563..4315
                     /locus_tag="RH288_004398"
     CDS             3563..4315
                     /locus_tag="RH288_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416077.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HDV4033372.1"
                     /translation="MNLEALPKYYSPKSPKLSDDAPATGTGCLTITDVMAAQGMVQSK
                     APLGLALFLAKVGVQDPQFAIEGLLNYAMALDNPTLNKLSEEIRLQIIPYLVSFAFAD
                     YSRSAASKARCEHCSGTGFYNVLREVVKHYRRGESVIKEEWVKELCQHCHGKGEASTA
                     CRGCKGKGIVLDEKRTRFHGVPVYKICGRCNGNRFSRLPTTLARRHVQKLVPDLTDYQ
                     WYKGYADVIGKLVTKCWQEEAYAEAQLRKVTR"
     gene            complement(4593..4682)
                     /locus_tag="RH288_004399"
     CDS             complement(4593..4682)
                     /locus_tag="RH288_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033373.1"
                     /translation="MNNPVCLDDWLIGFKSLCCTLAVIALLII"
     gene            complement(4737..4949)
                     /gene="cspF"
                     /locus_tag="RH288_004400"
     CDS             complement(4737..4949)
                     /gene="cspF"
                     /locus_tag="RH288_004400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspF"
                     /protein_id="HDV4033374.1"
                     /translation="MSRKMTGIVKTFDGKSGKGLITPSDGRIDVQLHVSALNLRDAEE
                     ITTGLRVEFCRINGLRGPSAANVYLS"
     gene            5250..5465
                     /gene="cspB"
                     /locus_tag="RH288_004401"
     CDS             5250..5465
                     /gene="cspB"
                     /locus_tag="RH288_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspB"
                     /protein_id="HDV4033375.1"
                     /translation="MSNKMTGLVKWFNADKGFGFISPVDGSKDVFVHFSAIQNDNYRT
                     LFEGQKVTFSIESGAKGPAAANVIITD"
BASE COUNT         1551 a         1220 c         1441 g         1552 t
ORIGIN      
        1 aatatgtctt taaagaaaag gctgatggcg aaaagtggcc cgatgagggc cacaatacgg
       61 ctgtcactta gacgtaaata tcaatggtgc cagcggtatt tgtatcgtct tttttctctt
      121 cttttttatc aggctgaact gtcgcgtctt cattcttttt ctctgcctgc tgccttaaca
      181 actgctccag ttgagcccag aggctttcaa tttgcttctg taccaatgca gccatttctt
      241 ttttctgctg tgtcgtcatc ccctcttccg atgagatttt cccaagcttt tcagtcagca
      301 cctgaatttg tcttgtgatt ttggctattt ctgatgttcc ttccggggcg gagttgtttg
      361 aaataacggt tgaggtattt ccctgaattg tgacagacat agatttctcc ttttaaaaaa
      421 gcactatcgg catgcacaaa aaaatcttta atcgtatttc ttgtgtcatt aattgtttga
      481 tgttcagatt gttttcctcg cgggctggcg cgcctcagaa agtaaagctt gttgacaggg
      541 gtaaacgttc ggcaataatt ttctgccgca tgcgggtgtt gcataaaacg tgttacgttc
      601 ctttatcgac aggtcaggtc accgctcacc cgccgacgag aaagcaacac tgacatgcta
      661 aagcaaaaaa tagatgaata agttgagttg tgcatatgta gcctgaccgt cacaaagtat
      721 atggtgtctg taccagtaag atgatggccg gactctttaa aaacgagctg acctgcacaa
      781 tacaggatgg acttagcaat ggctgctcct ggcacaaagc ggacagtgat caccgttctt
      841 acgactactt tctgacttcc ttcgtgactt gccctaagca tgttgtagtg cgatacttgt
      901 aatgacattt gtaattacaa gaggtgtaag acatgggtag cattaacctg cgtattgacg
      961 atgaacttaa agcgcgttct tacgccgcgc ttgaaaaaat gggtgtaact ccttctgaag
     1021 cgcttcgtct catgctcgag tatatcgctg acaatgaacg cttgccgttc aaacagacac
     1081 tcctgagtga tgaagatgct gaacttgtgg agatagtgaa agaacggctt cgtaatccta
     1141 agccagtacg tgtgacgctg gatgaactct gatggcgtat tttctggatt ttgacgagcg
     1201 ggcactaaag gaatggcgaa agctgggctc gacggtacgt gaacagttga aaaagaagct
     1261 ggttgaagta cttgagtcac cccggattga agcaaacaag ctccgtggta tgcctgattg
     1321 ttacaagatt aagctccggt cttcaggcta tcgccttgta taccaggtta tagacgagaa
     1381 agttgtcgtt ttcgtgattt ctgttgggaa aagagaacgc tcggaagtat atagcgaggc
     1441 ggtcaaacgc attctctgaa ccaaagcatg acatctctgt ttcgcaccga aggtgacact
     1501 tctgctttgc gttgacagga gaagcaggct atgaagcagc aaaaggcgat gttaatcgcc
     1561 ctgatcgtca tctgtttaac cgtcatagtg acggcactgg taacgaggaa agacctctgc
     1621 gaggtacgaa tccgaaccgg ccagacggag gtcgctgtct tcacagctta cgaacctgag
     1681 gagtaagaga cccggcgggg gagaaatccc tcgccacctc tgatgtggca ggcatcctca
     1741 acgcacccgc acttaacccg cttcggcggg tttttgtttt tattttcaac gcgtttgaag
     1801 ttctggacgg tgccggaata gaatcaaaaa tacttaagta gcgcgcaggg ataagaggga
     1861 tggtccctta aaggggagag ctaattatcc ggaaggattc tgatgatgaa catcgaagaa
     1921 ctgcgtaaaa ttttttgtga agatggcctc tatgctgtgt gcgttgaaaa tggaaatctt
     1981 gttagtcatt accgcattat gtgtttgcga aagaatgggg ctgcgttaat taattttgtg
     2041 gatgctcggg tcacggacgg atttatcttg cgcgaaggtg agtttgtcac ttcattacag
     2101 gcattgaaag agatcggaat aaaagctggc ttttctgctt tttcaggaga ataaactcat
     2161 ctacaatctt gcgcggggct gaactcccgc tgagtaacac cgtgccaccg gagaaaaccg
     2221 atggcacgca acgcaaaata ttacaattct gataattcgc ccgttcttgc ctgcacgcac
     2281 gggcggtatt ctcacgcatt caagtctgaa tggttccagc accctccatg cactgcagaa
     2341 caggccgaat ggctgattca ttcttaccgc aggcgcgggt tcgaggttaa gaaagctctc
     2401 agtctcgact atcggcactg gataatctct gtcaggctgc cttattccga acgcccacca
     2461 cgtgcgcccc gcactttcca gcaacggatc tggaggtaac gtgcgggtat tacttagacc
     2521 tgttctggtg cctgagcttg ggctggtggt ccttaagccg ggccgtgaat ccatacagat
     2581 atttcataat cctcgagtgc tggtggaacc ggaaccaaaa agcatgcgta atctgccatc
     2641 cggagtcgtt cctgccgttc gccagccgct ggcggaagac aaaacattgc tgccgttttt
     2701 tagtaacgaa cgggtgattc gtgctgctgg cggcgttggc gcattgtccg actggctatt
     2761 acgtcatgtt acatcctgcc agtggcctaa tggcgattac catcacactg aaacagtcat
     2821 tcaccgttat ggtaccggcg caatggtgtt gtgctggcac tgcgacaacc aactgcgtga
     2881 ccagacatcg gaatcactgg agctgcttgc tcaacaaaat ctgacagcat gggtgattga
     2941 cgtcatccgt cacgcaataa gcggtacgca ggagcgggaa ttatctttgg ctgaattatc
     3001 ctggtgggcg gtctgcaatc aggtggtgga tgcactacct gaggctgtat cgcgtcgttc
     3061 gctgggatta ccagcggaaa aaatctgctc ggtgtaccgc gaaagcgaca tcgtaccggg
     3121 agagcagacc gccaccagca tattgaaaca acgcacaaaa aatcttgcac cgttgcctta
     3181 cgcccaccag caacaaaaat caccacagga aatacggtgg taagcatcac cgttgatcca
     3241 gagtctccgg aatctttcat gaagctgcct aaacgtcgcc gctgggttaa ggagaaatac
     3301 acacgttggg ttaagacaca gccgtgtgct tgctgcggta tgccagccga cgatccgcat
     3361 catctgattg gtcacgggca gggcggaatg ggaacaaaag cacatgatct ctttgtgttg
     3421 cctttgtgca gaaagcatca caacgagctg catacggata cagtggcatt tgaagataag
     3481 tatggctccc aactggagct gatatttcgt tttatcgatc gcgcgctggc aattggcgta
     3541 ctggcgtaag tggagaacga gcatgaacct tgaagcctta ccaaaatatt actccccaaa
     3601 atctccaaaa ttgagcgatg acgctccagc gacaggcacc ggttgtttaa caattacgga
     3661 tgtaatggca gcgcagggga tggtgcagtc gaaagcacca cttgggttgg ccttatttct
     3721 ggcaaaagtt ggtgttcagg accctcagtt tgcgattgaa ggcctgctaa attacgcgat
     3781 ggcactggat aacccgacat tgaacaaatt gagtgaagaa atccggttac agattattcc
     3841 ttacctcgtg agttttgcct ttgctgatta ctccaggtct gcggcaagta aggctcgctg
     3901 tgagcattgt tcaggtacgg gattttataa tgtattgcgc gaagtggtga aacactacag
     3961 acgcggggaa tctgtaatca aggaagaatg ggtgaaggaa ctatgtcagc attgccatgg
     4021 taagggcgaa gccagcacag cgtgcagagg gtgtaagggt aaagggattg ttctggatga
     4081 aaaaagaacc cggtttcatg gcgtaccggt atataagatt tgtgggcgtt gtaatggaaa
     4141 ccggtttagt cgtttaccga ccacgctggc acgacgtcat gtccagaagc tggtaccaga
     4201 cctgaccgat tatcagtggt ataaggggta tgcggacgtc attggtaaac tggtaacaaa
     4261 gtgctggcag gaagaagcat acgcggaagc gcaattgagg aaggtgacga gataaatgat
     4321 ttttgctgaa gatggcgaca tgatgtttgc atttttcaaa aaatatggat aaaatttttt
     4381 caacgatggg ctttgtatac ccgacgttaa gaaaaagtag aaaacccgct gatgagcggg
     4441 ttttgtgctt taaatggggc aatggtaatg ttgaatctca tcccgggact catgtctgtt
     4501 aacttattat ttagctggtg acttggttat ttgcctgatg tttaaaatgt tttcttccag
     4561 tacaatgtcc ctaaacacaa tgagtctgct tattatatta ttagcagagc tattacggcc
     4621 aaagtacagc ataagctttt aaagccaatc aaccagtcat caagacagac ggggttattc
     4681 ataaaaactc tccatgtgtg atccgatggg gcctgaaatt aaagctttaa tatagctcat
     4741 gaaaggtaaa cattggcagc tgaagggcca cgcagaccat ttatccggca aaattccacg
     4801 cgtaatccgg tggtaatttc ttctgcatcg cggagattga gcgctgaaac atgaagctgg
     4861 acatcgatac gaccatcgga tggggtgata agacccttgc cgcttttgcc gtcaaaggtt
     4921 ttgacaattc ctgtcatttt acgggacaaa aaaattcctt aatactgata acttggcgca
     4981 ctatacacac gttcctgaag aaagctatag ttttttgatg gggttgaaga tggctggatg
     5041 tctaaaataa acattgcttc atatgttcaa ctatgcgtta atgattgcgt cggtttgaag
     5101 aacagacgat atacgaagta gtttactaaa gcagttctca tttcaggtgt tattcactta
     5161 ttccttcttt gagtctctcc aattaagtac gaagtcgttt ctgttatgca aaccatttat
     5221 gccgaaaggc tcaagttaag gaatgtagaa tgtcaaataa aatgactggt ttagtaaaat
     5281 ggtttaacgc tgataaaggt ttcggcttta tttctcctgt tgatggtagt aaagatgtgt
     5341 ttgtgcattt ttctgcgatt cagaatgata attatcgaac cttatttgaa ggtcaaaagg
     5401 ttaccttctc tatagagagt ggtgctaaag gtcctgcagc agcaaatgtc atcattactg
     5461 attaaaattc atcgctcgtc tgtatacgat aacgaagaag gctgatgcct gagtagagat
     5521 acggacagag tagtgaatat tggatctctt taataaaaag taaggaggtc caatacatga
     5581 aacaatggct agcatatttg gcaaaatctt aatcaggaaa agtatgctaa ccattgtggt
     5641 gaagtgcagg tttgctgcat gaatagtttt acagcagaag ctaactgctg gcatggcaaa
     5701 acaaagtgcg taagtggatg actcccacaa aaagcaccac aatctcaaac ccgctcaggc
     5761 gggt
//
LOCUS       DAPHKZ010000202         5723 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.203, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000202 DAPHKZ010000000
VERSION     DAPHKZ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5723
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.203"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(303..4883)
                     /gene="ypjA"
                     /locus_tag="RH288_004402"
     CDS             complement(303..4883)
                     /gene="ypjA"
                     /locus_tag="RH288_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417134.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin-like autotransporter YpjA/EhaD"
                     /protein_id="HDV4033376.1"
                     /translation="MNRTSPYYCRRSVLSLLISALIYAPPGMAAFTTNVIGVVNDETV
                     DGNQKVDERGTTNNTHIINHGQQNVHGGVSNGSLIESGGYQDIGSHNNFVGQANNTTI
                     NGGRQSIHDGGISTGTTIESGNQDVYKGGISNGTTIKGGASRVEGGSANGILIDGGSQ
                     IVKVQGHADGTTINKSGSQDVVQGSLATNTTINGGRQYVEQSTVETTTIKNGGEQRVY
                     ESRALDTTIEGGTQSLNSKSTAKNTHIYSGGTQIVDNTSTSDVIEVYSGGVLDVSGGT
                     ATNVTQHDGAILKTNTNGTTVSGTNSEGAFSIHNHVADNVLLENGGHLDINAYGSANK
                     TIIKDKGTMSVLTNAKADATRIDNGGVMDVAGNATNTIINGGTQNINNYGIATGTNIN
                     SGTQNIKSGGKADTTIISSGSRQVVEKDGTAIGSNISAGGSLIVYTGGIAHGVNQETG
                     SALVANTGAGTDIEGYNKLSHFTITGGEANYVVLENTGELTVVAKTSAKNTTIDTGGK
                     LIVQKEAKTDSTRLNNGGVLEVQDGGEAKHVEQQSGGALIASTTSGTLIEGTNSYGDA
                     FYIRNSEAKNVVLENAGSLTVVTGSRAVDTIINANGKMDVYGKDVGTVLNSAGTQTIY
                     ASATSDKANIKGGKQTVYGLATEANIESGEQIVDGGSTEKTHINGGTQTVQNYGKAIN
                     TDIVSGLQQIMANGTAEGSIINGGSQVVNEGGLAENSVLNDGGTLDVREKGSATGIQQ
                     SSQGALVATTRATRVTGTRADGVAFSIEQGAANNILLANGGVLTVESDTSSDKTQVNM
                     GGREIVKTKATATGTTLTGGEQIVEGVANETTINDGGIQTVSANGEAIKTKINEGGTL
                     TVNDNGKATDIVQNSGAALQTSTANGIEISGTHQYGTFSISGNLATNMLLENGGNLLV
                     LAGTEARDSTVGKGGAMQNLGQDSATKVNSGGQYTLGRSKDEFQALARAEDLQVAGGT
                     AIVYAGTLADASVSGATGSLSLMTPRDNVTPVKLEGAVRITDSATLTLGNGVDTTLAD
                     LTAASRGSVWLNSNNSCAGTSNCEYRVNSLLLNDGDVYLSAQTAAPATTNGIYNTLTT
                     NELSGSGNFYLHTNVAGSRGDQLVVNNNATGNFKIFVQDTGVSPQSDDAMTLVKTGGG
                     DASFTLGNTGGFVDLGTYEYVLKSDGNSNWNLTNDVKPNPDPIPNPKPDPKPDPKPDP
                     NPKPDPTPDPTPTPVPEKRITPSTAAVLNMAATLPLVFDAELNSIRERLNIMKASPHN
                     NNVWGATYNTRNNVTTDAGAGFEQTLTGMTVGIDSRNDIPEGITTLGAFMGYSHSHIG
                     FDRGGHGSVGSYSLGGYASWEHESGFYLDGVVKLNRFKSNVAGKMSSGGAANGSYHSN
                     GLGGHIETGMRFTDGNWNLTPYASLTGFTADNPEYHLSNGMKSKSVDTRSIYRELGAT
                     LSYNMRLGNGMEVEPWLKAAVRKEFVDDNRVKVNSDGNFVNYLSGRRGIYQAGIKASF
                     SSTLSGHLGVGYSHSAGVESPWNAVAGVNWSF"
     gene            complement(4948..5067)
                     /locus_tag="RH288_004403"
     CDS             complement(4948..5067)
                     /locus_tag="RH288_004403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDV4033377.1"
                     /translation="MPHSYAEYHHFIMMSLMSGEHNTLALSLQDESPGLVPVG"
     gene            complement(5222..5440)
                     /locus_tag="RH288_004404"
     CDS             complement(5222..5440)
                     /locus_tag="RH288_004404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDV4033378.1"
                     /translation="MKKLVRTSSAGNALLVCKLNRLGRSMWHLVVLLEELCERGINFR
                     ALAQSIFAQQWGDECCKSKTICDLKVIV"
BASE COUNT         1355 a         1505 c         1245 g         1618 t
ORIGIN      
        1 gcagagcatt aaaaacgcgt aagacgagca aatacaaaat aacactaaca cattgttttc
       61 aaacataatc tactgttttt actataataa aaatggtatg taggaatttc ggacgcgggt
      121 tcaactcccg ccagctccac caatcatgat tggacggtgt aaggacaaca ccaacaaaaa
      181 caggaagtta gaagtctcag caaaacaccg accagacggt gaggagacat aaaaggatac
      241 gcaaaggagc cgcggctcct ggtaacatga aagcccacag atgtgggctt tttcgttgat
      301 ggtcagaacg accagttcac accagctacc gcgttccacg gggattccac accggcacta
      361 tggctatacc ccaccccaag atgcccgctt aacgtactgc tgaatgaggc tttaatacct
      421 gcctggtata ttccacgtct gcccgacaaa taattgacga aattaccgtc actattcact
      481 ttcacccggt tatcatcgac aaattctttg cgcacagccg ccttcagcca cggctcaact
      541 tccataccgt tccccagacg catgttgtaa ctcagcgttg cgcccagttc acgatatata
      601 ctgcgggtat cgactgattt cgatttcatg ccattggata aatgatattc ggggttatca
      661 gcggtgaacc ccgttaacga tgcatacggc gtcaggttcc agttaccatc ggtaaatcgc
      721 atcccggttt caatgtgacc gcccagcccg ttgctgtggt aactgccatt ggcggctcca
      781 ccgctgctca ttttacctgc tacgttactt ttaaaacggt tcagcttcac gacaccgtcc
      841 agatagaaac cactttcatg ttcccaactg gcatagccgc ccagagaata actgcccaca
      901 ctgccatgtc ctccgcgatc aaaaccgata tgtgaatggg aatagcccat aaaagcgcct
      961 agcgtggtaa ttccttcagg aatatcatta cggctgtcga tccccactgt cattccggtc
     1021 agcgtctgct caaacccggc acccgcatcg gtggtgacat tattacgggt gttatacgtc
     1081 gccccccaga cattattgtt gtgtggactc gctttcatta tgttcaaccg ctcgcgaata
     1141 ctgtttagct cagcatcaaa taccaacggt aatgttgctg ccatattgag tacggctgcc
     1201 gtagaaggcg taatgcgttt ctccggaacg ggtgtcggcg ttggatcggg agtagggtct
     1261 ggttttggat ttgggtctgg ctttggatcg ggttttgggt ctggctttgg atttgggatg
     1321 gggtccgggt tgggtttgac atcattggtc aggttccagt tgctgttgcc gtcacttttc
     1381 aggacatact cataggtccc aagatcaacg aaaccgccgg tattgcccag cgtaaacgaa
     1441 gcatcccctc cccctgtttt caccagcgtc atcgcgtcgt cagactgtgg gctgacgccg
     1501 gtatcctgaa caaagatttt aaaattacca gtggcgttgt tgttgacgac cagttgatcg
     1561 ccccgggagc ctgcaacgtt ggtatgcagg tagaaattac cgctaccgga aagttcattg
     1621 gttgtcagcg tattgtagat accgttagtt gtggcaggcg ctgctgtttg tgctgacaaa
     1681 taaacatcac cgtcgttgag tagcaaactg tttactctat attcgcagtt gctggtacct
     1741 gcacaggaat tattgctgtt aagccagaca ctgccccggc tggcagccgt caggtcggca
     1801 agcgtggtat cgacgccatt tcccagagtc aatgtcgcgc tatcggtaat ccggaccgcc
     1861 ccttcgagtt taactggcgt aacattatcc cgtggcgtca ttaacgacag gcttcctgtc
     1921 gcgccactga ccgatgcatc cgccagcgta cctgcgtaga cgattgccgt accgccagcg
     1981 acctggagat cttctgcccg ggccagagcc tgaaactcat cttttgaccg cccaagggta
     2041 tattgcccgc cagagttaac ctttgtggcg gagtcctgac ccaggttttg cattgcccca
     2101 cccttgccaa ccgtggagtc gcgagcttcg gtacctgcta ataccaataa attaccgcca
     2161 ttttccagca acatattggt cgctaaattg ccggaaatgg aaaaagtacc gtactggtga
     2221 gtaccgctga tttcaatacc gttagccgtg ctcgtctgga gagcggcacc gctgttctgg
     2281 acgatatctg tcgctttgcc attatcgttg actgtcagcg taccgccttc attgatcttt
     2341 gtttttattg cctctccgtt agctgaaact gtttgtattc cgccgtcgtt aattgttgtc
     2401 tcattcgcca caccctcgac aatttgttca ccgccggtga gcgtcgtgcc tgtcgcagtg
     2461 gcttttgttt tgacgatctc ccgtccgccc atattgacct gtgttttgtc agaagaggtg
     2521 tctgactcca cggttaacac gccgccattt gccagcagga tattgttcgc cgcaccctgc
     2581 tcgatgctga acgcgacgcc atccgcgcgt gttcctgtga cccgcgtcgc cctggtggtt
     2641 gcaaccaaag cgccctggct actctgctgt atccccgttg cgctgccttt ctcccgcaca
     2701 tcgagtgtgc cgccgtcatt aagcaccgag ttttcagcca gaccgccctc attaactacc
     2761 tgtgaacccc cattaataat ggaaccttcc gctgtcccgt ttgccataat ttgttgtagg
     2821 ccagagacga tatcggtatt gattgcctta ccataattct gaacggtttg cgtgccacca
     2881 ttgatgtgtg ttttctctgt tgacccacca tcaacaattt gttcaccact ttcgatattt
     2941 gcttcagtgg ctaaaccata taccgtttgc ttgccacctt tgatatttgc tttatcagaa
     3001 gtggcactgg catatattgt ttgggtgcca gcactattga gtacagtgcc aacatctttt
     3061 ccataaacat ccattttgcc gttggcatta ataatcgtgt caactgcgcg ggaaccagtg
     3121 acgactgtta atgagccagc gttttccagc actacatttt tagcttctga attcctgatg
     3181 tagaaagcat caccataact gttggttcct tcgataagtg ttccggaggt cgtggaagca
     3241 attaatgcgc cgccggattg ttgctcaaca tgcttagcct caccaccgtc ctgaacctcc
     3301 agaacgccgc cattattaag tctggtgcta tctgttttag cctccttctg gacaatcagc
     3361 ttaccgccag tatcaatggt agtatttttc gccgaggttt tagccactac cgtcagttcg
     3421 ccggtatttt ccagcacaac ataattagcc tcccctccgg taatagtgaa gtgagagagc
     3481 ttgttgtatc cttcgatatc agtccctgca cccgtgttgg caactaaagc actgcccgtc
     3541 tcctggttaa ccccatgtgc aataccgccg gtatagacaa tcagcgagcc tccggcgcta
     3601 atattgctgc caattgccgt accatctttc tcaacaacct gccggctccc ggaggatata
     3661 attgttgtgt cagctttccc gccgcttttg atattttgcg ttccgctgtt gatattggtg
     3721 cctgtggcta tgccataatt attaatattc tgtgtgccac cattaattat ggtatttgtc
     3781 gcgtttcctg caacatccat aaccccgcca ttatctattc gggtcgcatc agctttagca
     3841 ttggttaaaa ctgacattgt tcctttatct ttaataatcg tcttgtttgc cgaaccatat
     3901 gcgtttatgt ctaaatgacc accgttttcc agcaacacat tgtctgccac gtgattgtgg
     3961 atggagaatg caccttcact attcgtaccg ctcaccgtcg taccgttagt gttagttttt
     4021 aaaattgcac catcgtgctg ggtaacattt gttgccgtac caccactaac atcaagcacg
     4081 ccaccagaat aaacttcaat aacatccgag gtgctggtgt tatcaacaat ttgcgtgcca
     4141 ccagaataga tatgcgtatt ttttgccgtt gacttactat tcagagactg agttccgcct
     4201 tcaatcgtcg tgtccagcgc acggctctca tatactcttt gctcaccgcc atttttaatg
     4261 gttgttgttt ctactgtgct ctgttcaaca tactgtcgac caccatttat ggttgtgttc
     4321 gttgccagac ttccttgtac tacgtcctga gagccagact tatttatcgt tgtaccatca
     4381 gcatgccctt gaacttttac tatctggcta ccaccatcaa tgagtattcc attcgcactc
     4441 cctccctcta cgcgtgaagc accgccctta attgtcgttc cattgctgat acccccttta
     4501 taaacgtcct gattgccact ctcgattgtc gtacctgtgg aaataccccc gtcatgaatt
     4561 gactgtctgc caccgttaat ggttgtatta ttagcctgcc ccacaaaatt gttatgactt
     4621 cctatatctt gatatccacc agattcaata agacttccat tagatacccc gccatgaaca
     4681 ttctgctggc catggttgat aatatgagtg ttatttgttg tacctcgttc atccactttt
     4741 tggttgccat ctacagtctc atcgtttacc acaccaataa cattagtagt gaaggcagcc
     4801 atcccgggcg gggcatatat caaggcagat atcaataagg aaagtactga gcggcgacaa
     4861 taatagggac tggtcctgtt cataaatttc atcctctgaa aagtgaatac tgagtagcgt
     4921 ttaagcgacc ttagctttgc tgcaacatca gcccacaggc accagaccag gggattcatc
     4981 ctgaagagac agcgcaagtg tattgtgttc accgctcatc aaagacatca tgatgaaatg
     5041 atgatattcc gcataagaat gaggcatttt ttaaacgcag tgcgctgaag tgtggttgga
     5101 taaaaaagtc aatccattca ggaaatacgg gcgtattctt ttctttcgac aatgaggccg
     5161 ttggcaaaat aaaatgattt acataatcgt ttctgatgaa tatcttctgc tcacataaaa
     5221 atcacacaat aactttgaga tcgcagattg ttttactttt acagcattcg tccccccatt
     5281 gttgggcaaa tatagattgg gccagagcac gaaagttaat accacgttcg cacagctcct
     5341 ccaacagcac gacaagatgc cacatactgc gccccagtcg gttcagttta cagactagca
     5401 gtgcgttccc tgccgatgat gtcctgacca gttttttcag tccggacctc ctgccacggt
     5461 tttacgttga agtggtaacc ctgagcacgc agttcttcag tcaggcgtgg tgcaccgtaa
     5521 cgctgttatt gctgggtaag atcaaaaaac tttcaggcag ctaaggaaag ttgaaccaga
     5581 cattagatga aatatttcaa ccaattacag caccaattca gtcactgcca gcccaccaaa
     5641 taaatcaagg ggttacatga aaacgtagcc cctttttctt tggtagtgac actaaaatgg
     5701 atgtagtgtg aagaataatc ccg
//
LOCUS       DAPHKZ010000203         5664 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.204, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000203 DAPHKZ010000000
VERSION     DAPHKZ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5664
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.204"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..320
                     /locus_tag="RH288_004405"
     CDS             <1..320
                     /locus_tag="RH288_004405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033379.1"
                     /translation="GNPENFKEDFQEKLNKVIKTLNVSKKKDEEKVSLDNLSVIEESK
                     LELVSAVRYSAQYVPMFTLTLDKKEITMPKNTVIFPFASDETAKYLNEQQQKYKDSLF
                     LTR"
     gene            382..1710
                     /locus_tag="RH288_004406"
     CDS             382..1710
                     /locus_tag="RH288_004406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA circularization N-terminal domain-containing
                     protein"
                     /protein_id="HDV4033380.1"
                     /translation="MTWKDRLQDASFRGVPFKVEEESAGTGRRVETHEYPNRDKPYTE
                     DLGKITFRPSITAYVVGDDCFDQRDRLIDALNKPGPGTLVHPTYGELKVCVDGEVRVS
                     TSKSEGRIVRFDLKFVEAGELSYPTSGAATAQTLMSSCSALDDCISDSFSGFSIDGVA
                     DFVQNDVVGNASTMLGYVSDAMKVVDSAVSDAARLLQGDISVLLPPPSSGKNFVEQVQ
                     KMWRTGKRLYGNASDLVTMIKTLSGVSLGSDLQPRGVWKTDSKTTATATQQRNVVAST
                     LRTTAISEAAYAVTRLPAPTTSAVMQNSAVGQATTPAQSTGWPSVTHPALNNAPAVKN
                     TVDLPTWEELTDIRDTLNTAIDKELSRTTSDALFLALRRVKADLNADINTRLEQSARI
                     IQRTPDEILPALVLAATWFDNAARDADIIRRNAITHPGFVPVIPLKVPVQ"
     gene            1707..2786
                     /locus_tag="RH288_004407"
     CDS             1707..2786
                     /locus_tag="RH288_004407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate protein"
                     /protein_id="HDV4033381.1"
                     /translation="MNDNVTLRVNGREWNGWTSVRIGAGIERLARDFSVEITRQWPGD
                     EGITTLQPRIKNGSKVEVLIGDELVITGWVEATPVRYDARSVSTGIAGRSLTADLIDC
                     AAEPTQFNGRSLVQIAQALAAPFGIEVVNSGAPSGVIPDVQPDHGETVIEVINKILGQ
                     QQALAYDDPHGRLVIGGIGSTRAHTALVLGENILSCDTEKSIRERFSVYQVAGQRAGN
                     DDDFGEVTTTALRARTEDAFIARYRPMYIRQTGQATGAGCIARADFEARQRAARTDET
                     TYVVQGWRQGNGTLWQPNQRVIVFDPVCGFDNTELLVSEVTFTQDQNGTLTEIRVGPP
                     DAYLPEPEAPGARKKKKARVQEDPF"
     gene            2786..3334
                     /locus_tag="RH288_004408"
     CDS             2786..3334
                     /locus_tag="RH288_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015364403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein"
                     /protein_id="HDV4033382.1"
                     /translation="MRTIEAMQRQLLGLIARAVVKSISAATKCQTVDVSLIAGEPKAG
                     VEHLEPYGFTARANSGAEAVVLFPDGDRSHAVVVTVSDRRYRLKGLQTGEVAVYDDQG
                     QSVTLTREGIVVDGAGKTITFRNSPKARFEMDLEVTGQVKDLCDSSGTTMSAMRLAYN
                     GHRHRENGQGSNTDKPDKAMEA"
     gene            3334..3759
                     /locus_tag="RH288_004409"
     CDS             3334..3759
                     /locus_tag="RH288_004409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage GP46 family protein"
                     /protein_id="HDV4033383.1"
                     /translation="MELWLTVNGKRTCASAPLDPLTRAVVISLFTWRRAEPDDNADVP
                     MGWWGDTWPAVQNDRYGSRLWLLQRSKLTNQLVQTVRGYIRECLQWMIDDGVVSRIDL
                     DIRRTGINELGNSITLWRRDGPVMISFDDLWSAITHGGQ"
     gene            3746..4804
                     /locus_tag="RH288_004410"
     CDS             3746..4804
                     /locus_tag="RH288_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDV4033384.1"
                     /translation="MADSEFQRPTLAENISMLRNDLFARLDVSDTLRRMDEDVRAKVY
                     AAALHTVYGYIDYLAMNMLPDLCDEFWLARHAAMKRCPRKGATAASGYMRWEGVSDGL
                     KVTAGSVIQRDDLVQYTATADATSSGGVLRVPIACSSSGAVGNADDGTSLILVTPVNG
                     LPSSGVADTLTGGFDTEDLETWRARIIERYYWTPQGGADVDYVVWAKEVPGITRAWTY
                     RHWMGTGTVGVMIASSDLINPIPEESTETAARQHIEPLAPVAGSDLYVFRPVAHKVDF
                     HIRVTPDTPEIRAAITAELRSFLLRDGYPQGELKVSRISEAISGANGEYSHQLLAPAD
                     NISIAKNELAVLGTISWT"
     gene            4795..5379
                     /locus_tag="RH288_004411"
     CDS             4795..5379
                     /locus_tag="RH288_004411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HDV4033385.1"
                     /translation="MDVTNDDYIRLLSALLPPGPAWSASDPAIAGAAPSLTRVHQRAD
                     ALMRELDPRTTTELINRWERLCGLPDECIPAGTQTLRQRQQRLDAKVNLAGGINEDFY
                     LAQLAALGRPDATITRYDKSTFTCSSACTDAVNAPEWRYYWQVNMPAATNTTWMTCGD
                     PCDSALRIWGDTVVECVLNKLCPSHTYVIFKYPE"
     gene            5383..>5664
                     /locus_tag="RH288_004412"
     CDS             5383..>5664
                     /locus_tag="RH288_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033386.1"
                     /translation="MHRIDTKTAQKDKFGAGKNGFTRGNPQTGTPATDLDDDYFDMLQ
                     EELCSVVEASGASLEKGRHDQLLTALRALLLSRKNPFGDIKSDGTVKTAL"
BASE COUNT         1299 a         1441 c         1709 g         1215 t
ORIGIN      
        1 acggcaatcc tgaaaacttt aaggaggatt ttcaggagaa attaaataaa gtaataaaaa
       61 ctttaaatgt gtcaaagaaa aaagatgaag agaaagttag cctggataat ttaagtgtta
      121 ttgaagagtc taaactagag ctcgtttctg cggtgcgtta ctctgctcag tatgttccta
      181 tgtttactct gacgctggac aaaaaagaaa ttaccatgcc taaaaatacg gtaatatttc
      241 catttgccag cgatgaaaca gctaagtatt taaatgaaca acagcaaaag tataaagatt
      301 cgttgtttct gactcgctaa ttaataaaat tcattacaag gccaccttct aataggtggc
      361 tttttaattt tcggagtata tatgacgtgg aaagacagac ttcaggacgc gtcatttcgc
      421 ggtgtgccgt ttaaggttga agaagaaagt gcgggaaccg gtcgtcgtgt ggaaacacat
      481 gaatacccga accgcgacaa gccctatacc gaagacctgg ggaaaatcac tttccgcccg
      541 tccatcacgg cttatgtggt gggagatgac tgctttgacc agcgcgatcg cctgattgac
      601 gcactgaata aacccggtcc cggcacgctt gtccatccga cttacggtga gctgaaagtc
      661 tgtgttgacg gagaggttcg ggtcagcaca tcgaagagtg aagggcgtat tgtccgcttt
      721 gacctgaagt ttgtcgaagc gggagaactc tcttacccca catcaggtgc ggcgacggcg
      781 cagacgctga tgtcatcctg ttctgcactg gatgactgca tcagtgacag cttcagcggt
      841 ttcagtatcg atggcgtggc ggattttgtg cagaacgacg tcgtcggtaa tgccagcaca
      901 atgcttgggt atgtttctga tgcgatgaaa gtggtggatt ctgccgtatc ggatgctgcc
      961 aggctgttgc agggggatat ctcggtactt ctgccgccac catcgtcagg caaaaatttc
     1021 gttgagcagg tgcagaaaat gtggcgtacc gggaaacgcc tttatggtaa cgccagcgac
     1081 ctggtcacca tgatcaaaac gctttccggt gtcagcctcg gcagcgatct gcaaccgcgc
     1141 ggcgtctgga aaacggacag taaaaccact gccacggcga cgcagcagcg taacgtggtt
     1201 gccagcaccc ttcgtacgac cgcaatcagc gaagcggcgt atgccgtcac ccgattgcct
     1261 gcgccaacaa cttccgcggt gatgcagaat tccgcagtgg ggcaggcaac aacacccgcg
     1321 cagagcactg gctggccttc cgtcacgcat ccggcactga acaatgcacc ggcggtgaaa
     1381 aacacggttg acctgccgac gtgggaagaa ctgactgaca ttcgcgacac actgaatacg
     1441 gcaattgata aggagttgtc ccgtacaacc agcgatgcgc tgtttctggc gctgcgccgg
     1501 gtgaaagcag atctgaatgc ggatatcaac acgcgccttg aacagtctgc acggatcatt
     1561 cagcgcacac cggatgagat tttacccgcg ctggtgctgg cggcgacctg gtttgataac
     1621 gcggcgcgtg acgcggacat tatccggcgt aatgccatta cgcatcccgg ctttgtgccg
     1681 gtgatccctc tgaaggtgcc agtgcaatga acgacaatgt cacgctacgg gtaaatggcc
     1741 gggagtggaa tggctggaca tcggtccgca tcggtgccgg tattgaacgg ctggcgcggg
     1801 atttcagtgt ggagatcact cgccagtggc cgggagatga gggtatcacc acgcttcagc
     1861 cgcgcattaa aaacggttca aaagtggaag tgctgattgg tgatgagctg gtgatcaccg
     1921 gctgggtgga ggcgactccc gttcgttacg atgcccgttc ggtcagcacc ggtattgccg
     1981 gacgtagtct gacggctgac ctgattgact gtgcagccga accgacacag tttaacggac
     2041 gctcgctggt gcagattgcg caggcgcttg ctgcgccttt cggcattgag gtggtgaaca
     2101 gcggtgcgcc gtcgggtgtt attcctgatg ttcagcctga tcacggtgaa acggtgattg
     2161 aggttatcaa caaaatactc ggtcagcagc aggcgctggc ttacgacgat ccgcacggca
     2221 ggctggtgat tggcggtatt ggctcaacgc gggcacatac cgcgctggta cttggggaaa
     2281 acatcctttc ctgtgatacg gagaagagta tccgggagcg gttttctgtt taccaggtgg
     2341 cggggcagcg tgccggaaac gacgatgatt tcggtgaggt caccaccacc gcgctgcggg
     2401 cccgcacaga ggacgcattt attgcccgtt accgtccgat gtatatcagg cagacagggc
     2461 aggccacggg ggcaggctgt attgcgcgtg ctgactttga agcccgacaa cgggcggcgc
     2521 ggacggatga aaccacctat gtggtgcagg gctggcgaca gggtaacggt acgctgtggc
     2581 agcccaacca gcgggtgatt gtcttcgatc cagtctgtgg tttcgacaat accgaactgc
     2641 ttgtctcgga agtcacgttt actcaggacc agaacggcac cctgacggaa atccgtgtcg
     2701 gcccgcctga tgcttatctg cctgaacccg aagcccccgg cgcgcggaaa aagaaaaaag
     2761 ccagagtaca ggaggacccg ttctgatgag gacgattgaa gccatgcagc gacaacttct
     2821 cggcctgatt gcgcgggcag tggtgaaaag catcagtgcc gccacgaaat gtcagaccgt
     2881 ggatgtgtcc ctgattgccg gtgaacccaa agccggggtt gaacatcttg aaccctacgg
     2941 ttttaccgca agggcaaaca gcggcgcgga agcggtggtg ttgtttccgg atggcgaccg
     3001 ttctcatgcg gtggttgtta cggtgtcgga ccggcgctac cgcctgaaag ggttgcagac
     3061 gggtgaggtg gctgtctatg acgatcaggg gcagtctgtg acgctgaccc gggaggggat
     3121 cgtggtggac ggtgcaggta aaacgatcac gtttcgcaat tcacctaaag cacgttttga
     3181 aatggacctg gaagtgacag gacaggtgaa agacctgtgc gactccagcg gcactaccat
     3241 gtcagcgatg cggcttgcct ataacgggca tcgtcacaga gagaacggtc agggcagtaa
     3301 caccgacaaa ccggataaag cgatggaggc atgatggaac tgtggctgac ggtgaacggt
     3361 aaacgcacct gcgccagcgc accgctggat ccgctgaccc gcgccgtggt gatttccctg
     3421 tttacctggc ggcgggcgga gcctgatgac aacgccgacg tcccgatggg atggtggggg
     3481 gatacctggc ctgcggtaca gaatgaccgt tacggctcac gactgtggct gcttcagcgc
     3541 agcaaactga ccaatcagct ggtgcagaca gtaagggggt atatccgcga atgcctgcaa
     3601 tggatgattg atgacggcgt ggtgtcccgt attgatctgg atatccgccg caccgggatt
     3661 aatgagctgg gtaacagtat caccctctgg cgtcgtgacg gaccggtaat gatttctttt
     3721 gatgatctgt ggagtgcgat aacgcatggc ggacagtgaa tttcagcgcc cgacgctggc
     3781 agaaaatatc agtatgctcc gtaacgattt attcgccagg ctggacgtca gcgacacgct
     3841 ccggcgcatg gatgaagacg tgcgggcaaa ggtgtatgcg gcggcgctgc atacggttta
     3901 cgggtacatc gattatctgg caatgaacat gctgcctgac ctgtgcgatg agttctggct
     3961 ggcgcgacat gctgcgatga aacggtgtcc acgcaagggg gccacggctg ccagcgggta
     4021 tatgcgctgg gaaggtgtca gcgatggcct gaaggtgacc gccgggagtg ttattcagcg
     4081 cgatgacctg gttcagtaca cggcaactgc cgatgcaacc agctccggtg gtgtcctgcg
     4141 cgtgccgatc gcctgctcaa gttcaggcgc ggtcggtaac gctgacgacg gtacgtcatt
     4201 aatcctggtc acgccggtga atggtctgcc gtcttccggt gtggctgaca ccctgacagg
     4261 cggatttgat actgaagatc tggaaacgtg gcgcgcccgc atcattgagc ggtattactg
     4321 gacgccgcag ggcggggctg acgtggacta tgtcgtctgg gctaaagaag tgcccggcat
     4381 tacccgcgca tggacatacc gtcactggat gggaacggga actgtcggtg tgatgattgc
     4441 cagcagtgac ctgattaatc ccattccgga agaatcaacg gaaacggcgg caagacaaca
     4501 cattgagcca ctggccccgg tggcaggctc tgatttgtat gtattcaggc cggtggcgca
     4561 taaagtggat tttcatatcc gcgtgacgcc ggacacaccg gaaatacggg ctgccatcac
     4621 cgcagagttg cgttcgttcc tgctgcgtga tggttatcct cagggagaac tgaaggtatc
     4681 gcgtatcagt gaggcgattt ccggtgcgaa cggggaatac agccatcagt tgcttgcccc
     4741 ggcggacaat atctccattg caaaaaatga actggcggtt ctggggacga tttcatggac
     4801 gtgacaaacg atgattacat ccgcctgtta tcggcactgt tgccgcccgg tcctgcatgg
     4861 tcagccagcg atccggcgat tgccggtgcg gcaccttcat taacccgcgt tcatcagcgt
     4921 gcggatgccc tgatgcggga gctggatccg cgcaccacca ctgaactgat aaaccgctgg
     4981 gagcgtctgt gcggtctgcc ggatgaatgt attcccgcag ggacacagac ccttcgccag
     5041 cgtcagcaac ggctggatgc gaaggttaat ctggcgggcg gcatcaatga ggatttttac
     5101 cttgcacagc ttgctgccct gggcagacca gacgctacta tcacgcgata cgataaaagc
     5161 acgttcacct gctcatcggc ctgtactgac gcagtgaatg cgccggaatg gcggtattac
     5221 tggcaggtca acatgccagc cgccaccaac accacctgga tgacatgtgg cgatccctgt
     5281 gattccgcac tgcgtatctg gggcgacacc gttgtcgagt gcgtgcttaa caaactctgc
     5341 ccttcgcata cctacgtaat ttttaaatat ccggagtaat ccatgcatcg tatagacacg
     5401 aaaaccgcgc agaaggataa gttcggcgcg ggtaagaacg gttttacccg tggtaacccc
     5461 cagaccggca cacctgccac cgatctggat gatgactact ttgacatgtt gcaggaagaa
     5521 ctttgtagcg tggtggaggc ctccggtgcc agcctggaga aagggcggca tgaccagcta
     5581 cttaccgcgc ttcgcgcgct gctgttaagc cgcaagaatc cgtttggcga tatcaaatcg
     5641 gatggcacgg tgaaaacggc tctc
//
LOCUS       DAPHKZ010000204         5598 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.205, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000204 DAPHKZ010000000
VERSION     DAPHKZ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5598
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.205"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..529
                     /locus_tag="RH288_004413"
     CDS             <1..529
                     /locus_tag="RH288_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV4033387.1"
                     /translation="HADGITFGQPLGDTMVLVKAPGADNVKIENQTGIHTDWRGYAIL
                     PFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQIGGKVLMTLKYG
                     NKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGKDKNSNCIVEYKLPE
                     VSPGTLLNQQTAICR"
     gene            543..1073
                     /locus_tag="RH288_004414"
     CDS             543..1073
                     /locus_tag="RH288_004414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4033388.1"
                     /translation="MKYNNIIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDS
                     LNFTVDLQKNSARQFPTTGSTSPAVPFQITLSECSKGTTGVRVAFNGIEDAENNTLLK
                     LDEGSNTASGLGIEILDGNMRPVKLNDLHAGMQWIPLVPEQNNILPYSARLKSTQKSV
                     NPGLVRASATFTLEFQ"
     gene            1086..1589
                     /locus_tag="RH288_004415"
     CDS             1086..1589
                     /locus_tag="RH288_004415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV4033389.1"
                     /translation="MKRLHKRFLLATFCALFTATLQAADVTITVNGRVVAKPCTIQTK
                     EANVNLGDLYTRNLQQPGSASGWHNITLSLTDCPVETSAVTAIVTGSTDNTGYYKNEG
                     TAENIQIELRDDQDATLKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALI
                     NVIYTWQ"
     gene            1649..2563
                     /locus_tag="RH288_004416"
     CDS             1649..2563
                     /locus_tag="RH288_004416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4033390.1"
                     /translation="MGKTISMKLLFGIYLLLMAGKVFAFSCNVDGGSSIGAGTTSVYV
                     NLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNN
                     VTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKAGEVIARIHMYKIATL
                     GSGNPRNFTWNIISNNSVVMPTGGCTVDSRNVTVNLPDFPGSAEIPLGVYCSSEQKLS
                     FYLSGATTDSARQVFANTAPDATKASGVGVSLMRNGKILATGENISLGTVNKSKVPLG
                     LSATYGQTGNKVSAGTVQSVIGVTFIYE"
     gene            2897..5176
                     /gene="ydeP"
                     /locus_tag="RH288_004417"
     CDS             2897..5176
                     /gene="ydeP"
                     /locus_tag="RH288_004417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance putative oxidoreductase YdeP"
                     /protein_id="HDV4033391.1"
                     /translation="MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKP
                     EGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHE
                     LEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
                     FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHN
                     PGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYY
                     NVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEW
                     KDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNI
                     GKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPHAPGHAAIASMQA
                     ICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILP
                     VLGRSEIDMQKNGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQAALPQS
                     VVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANF
                     ITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAK
                     ICRVKNGERVNLVALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHD
                     PLSGIPGYKSIPVELEPSN"
     gene            5424..>5598
                     /gene="safA"
                     /locus_tag="RH288_004418"
     CDS             5424..>5598
                     /gene="safA"
                     /locus_tag="RH288_004418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system connector SafA"
                     /protein_id="HDV4033392.1"
                     /translation="MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLG
                     ISEMGRIARDLTHF"
BASE COUNT         1574 a         1234 c         1311 g         1479 t
ORIGIN      
        1 tcatgctgat ggcatcacct ttggacagcc gctgggcgac acaatggttc tggttaaggc
       61 tcctggcgct gataatgtca aaatagagaa ccagaccgga attcataccg actggcgtgg
      121 ctatgccata ttaccatttg cgacagaata tagagaaaat cgtgtcgctc ttaacgcgaa
      181 ttcccttgca gataatgttg aactggatga aaccgtggtc actgtcatcc caactcacgg
      241 tgctattgcc agagcaacat ttaatgcaca aatcggcggg aaagtattaa tgacgttgaa
      301 gtacggtaat aagagcgttc cattcggtgc aattgtcaca catggagaga ataaaaatgg
      361 cagcattgtc gcggaaaacg gtcaggttta tctgactgga cttccacagt cagggaaatt
      421 acaggtttca tggggcaagg ataaaaactc aaactgtatt gtcgagtaca agcttcctga
      481 agtttctcct ggtaccttac tgaaccagca gacagcaatc tgtcgctaag gaacaataga
      541 ttatgaaata caataacatt attttcctcg gtttatgtct ggggttaacc acctattctg
      601 ctttatccgc agatagcgtt attaaaatta gcgggcgcgt cctcgattat ggctgcacag
      661 tctcatcgga ttcgcttaat tttaccgtag atctccaaaa aaacagtgcc agacaatttc
      721 caacgaccgg tagcacaagt ccagccgtcc cttttcagat tacgttaagt gaatgcagta
      781 aagggacaac gggggttcgg gttgcattta acggtattga ggatgcagaa aataatactc
      841 tgttgaaact ggatgaagga agcaatacgg cctccggttt gggtatagaa atactggacg
      901 gaaatatgcg tccggtgaaa ttgaatgacc ttcatgccgg gatgcagtgg atcccactgg
      961 taccagaaca gaacaatatt ttgccttact ccgctcgtct gaagtcaact cagaagtccg
     1021 tcaatccggg actggtgagg gcttcggcaa cctttaccct tgaatttcaa taatcagagt
     1081 cagatatgaa aagacttcac aagaggttcc tgttagctac gttttgcgcg ttattcacag
     1141 caactctcca ggccgccgat gtcactatca ctgttaatgg tcgggtagtc gctaaaccct
     1201 gcactattca aaccaaagaa gctaacgtta atctcgggga tctttatacg cgcaatctgc
     1261 aacaacctgg ttctgcatca ggctggcaca atattacttt gtcattaacc gattgtccgg
     1321 ttgaaacaag tgcagtgacg gcaatcgtga caggttcaac tgacaatacg ggttattaca
     1381 aaaatgaagg tactgccgaa aatattcaga tagagctaag ggatgaccag gatgcgacgt
     1441 taaaaaatgg cgatagcaaa acggttattg ttgatgagat cactcgtaat gcacagtttc
     1501 cacttaaggc aagagctatc acggtgaatg gaaacgcaag ccagggaacg atcgaggcgc
     1561 taatcaatgt gatctacacc tggcaataac gtcgattcga ttttcttagc ctccttttta
     1621 aatcaatttt ttaaccttag gatatatcat gggtaaaaca ataagtatga agcttctgtt
     1681 cggtatttat cttctattaa tggcaggcaa agtttttgcc ttcagttgta atgtcgatgg
     1741 cgggtcaagt attggagcag gtacaacctc tgtttatgtt aatctcgacc ctgtaataca
     1801 accgggccag aatctggttg tagacttgtc tcagcatatc agttgctgga atgattacgg
     1861 cggctggtac gacactgatc atataaacct ggtacaaggc tcagctttcg caggctctct
     1921 acagtcatat aaaggatcgc tgtactggaa taatgtgacc taccccttcc cgttgacgac
     1981 aaatactaat gtattagata ttggtgataa gacaccgatg ccattaccgt taaaactcta
     2041 tatcacccca gttggggcgg ccggtggagt tgtcataaaa gcgggggaag tcattgcccg
     2101 tattcatatg tataaaattg caacattagg aagcggaaat ccgcgtaatt ttacgtggaa
     2161 tattatttca aataacagtg ttgttatgcc aacaggcggc tgcactgttg atagtcgtaa
     2221 tgtcaccgtg aatctcccgg actttcctgg aagcgcagaa ataccccttg gcgtatattg
     2281 ctcaagcgaa caaaagctct cattttatct ttcgggtgcc accactgaca gtgcccgaca
     2341 agtgtttgct aacacagcac ctgatgcgac aaaagcatcg ggagtgggtg tctctctgat
     2401 gcgtaatgga aaaatactgg ctacgggaga aaatatctcc ctggggacag taaataaaag
     2461 caaagtacct ctgggtttaa gcgcaaccta tggacaaaca ggaaacaagg tttcagccgg
     2521 aaccgtccag tcagtcattg gtgtcacttt tatctatgaa taattgtgat tttgacctta
     2581 gtctatgcgc tccattcacg aaaattgcgc ggataattat tttgtgaagg ctattatcct
     2641 acacctgtaa gaatatccgc gcaaaattga agccagaatc ttatttttta tattgaaaaa
     2701 catgttaatt taaacactat gagagatgat gcttaactta tcgtatttaa tctattgttt
     2761 aacgataata gagtaaaaat agaaagagag tagtccccta ctcttatata tccaggttga
     2821 cgataaaccc tttgtatata ctgtgcatca tcgctattac aaatcctaat aattcatttc
     2881 cacacaggat aagcagatga agaaaaaaat tgaatcctac cagggagctg ccggtggttg
     2941 gggtgctgtt aaatccgtag caaatgcagt acgtaagcag atggatatac gccaggatgt
     3001 tattgccatg tttgacatga ataagccaga gggctttgac tgtccgggtt gtgcatggcc
     3061 agatcctaag cacagtgcgt cattcgacat ttgtgaaaac ggcgcaaaag caatcgcctg
     3121 ggaagtcacg gataagcagg taaatgcctc tttctttgct gagaatacgg ttcaatcatt
     3181 acttacctgg ggagatcacg agcttgaggc tgcgggacgt ctcactcagc ctttgaaata
     3241 tgatgctgtc agcgactgtt acaagccatt aagctggcaa caagctttcg acgaaattgg
     3301 cgcacgcctt caaagctata gtgatcccaa tcaggttgaa ttctatactt cgggccgcac
     3361 ttccaatgaa gctgcctttc tttatcagct ttttgcccgt gaatacggga gcaataactt
     3421 tcccgactgc tccaacatgt gccatgaacc gaccagtgtg ggtttggcag cgagtatcgg
     3481 tgtgggtaaa gggactgtgt tgctggaaga ctttgagaag tgcgatttag tcatttgcat
     3541 tgggcataac cctggtacaa accacccccg catgctgact tcgttgcgcg ctttagtgaa
     3601 acggggagcg aaaatgatcg ccatcaatcc tctacaggaa cgtggcctgg agcgatttac
     3661 cgcaccgcaa aacccatttg aaatgctgac gaactctgag actcagttgg ctagtgccta
     3721 ctataacgtg cgcattggtg gcgatatggc gttgctcaag gggatgatgc gcctgttaat
     3781 tgagcgcgat gatgctgcaa gcgccgcagg tcggccctca ttgctggatg acgaatttat
     3841 tcaaacgcat accgtcggct ttgacgagct acgccgtgac gttctcaatt ccgagtggaa
     3901 agatatcgaa cgtatttctg gattaagtca gactcaaatc gccgaactgg ctgacgcata
     3961 tgccgctgcc gaacgcacca ttatctgtta cggaatgggg atcactcagc acgaacatgg
     4021 tacccagaat gtacagcaac tggtcaattt gctgttgatg aaaggtaaca ttggcaagcc
     4081 tggtgcgggt atctgcccac tacgtggtca ctctaatgta cagggcgacc gaaccgtcgg
     4141 tatcaccgag aaaccgtctg cagagtttct ggctcgcctg ggtgagcgct atggcttcac
     4201 cccacctcat gcacctggac atgctgcaat tgccagcatg caagcaatat gtacggggca
     4261 ggctcgagca ttgatctgca tggggggcaa ttttgcgctg gcaatgccag atcgggaagc
     4321 gagcgctgta ccgttaacgc aattagatct ggcggtacac gtagccacta agcttaaccg
     4381 ctctcatctg ttgaccgcac ggcatagcta tattctgccg gttctgggac gtagcgagat
     4441 tgacatgcaa aaaaacggtg cgcaggcggt aaccgttgag gattcaatgt cgatgattca
     4501 tgcctcgcgt ggcgtgttaa aacccgccgg tgtaatgctg aaatcagagt gtgcagtggt
     4561 cgcgggaatc gcgcaggcag cactacccca gagcgtggta gcctgggagt atctggtgga
     4621 agattatgat cgcattcgca atgacattga agctgtgtta ccagagttcg ccgactataa
     4681 ccagcgcatc cgacatcctg gaggttttca cctgataaat gcagctgctg aaaggcgctg
     4741 gatgacgccg tcaggtaagg ctaatttcat taccagcaaa gggctgttag aagatccctc
     4801 ttcagcgttt aacagtaagc tggtcatggc gacagtacgc agccacgatc agtacaacac
     4861 gacgatttat ggtatggatg atcgctatcg aggggtattc ggtcaacgag atgtggtctt
     4921 tatgagtgct aaacaagcta aaatttgccg tgtaaaaaac ggcgaaagag ttaatcttgt
     4981 tgcgcttacg ccagacggta agcgcagctc acgccgcatg gatagattaa aagtggtcat
     5041 ttaccctatg gctgaccgct cactggtgac ctattttcca gaatcgaatc acatgctaac
     5101 acttgataac cacgatccat taagtggcat tcctggctat aaaagtattc cggttgaatt
     5161 agaaccatca aattaatgcc tcttctcatt tcttctgctg tcatccgcac agcagaagaa
     5221 tccctcattg actattatcg cgcaatttgc tcacatggat taaattaaac tacatactat
     5281 aagatataaa cttctgccta cagctgtaag aaaccccgct cagtactgaa gtgccagtcc
     5341 tatttcctct tttctccagc ctgttatatt aagcatactg attaacgatt tttaacgtta
     5401 tccgctaaat aaatatattt gaaatgcatg cgaccacagt gaaaaacaaa atcacacaaa
     5461 gagacaacta taaagaaatc atgtctgtaa ttgtggttgt cttattactg acccttacgt
     5521 tgatagccat tttttcggca attgatcagc tgggtatttc agaaatgggt cgcattgcaa
     5581 gagatcttac acatttca
//
LOCUS       DAPHKZ010000205         5595 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.206, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000205 DAPHKZ010000000
VERSION     DAPHKZ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5595
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.206"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(96..2165)
                     /gene="glyS"
                     /locus_tag="RH288_004419"
     CDS             complement(96..2165)
                     /gene="glyS"
                     /locus_tag="RH288_004419"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDV4033393.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLDAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDK
                     LEPYFTEGRYQDALVALAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRV
                     ADISLLQ"
     gene            complement(2175..3086)
                     /gene="glyQ"
                     /locus_tag="RH288_004420"
     CDS             complement(2175..3086)
                     /gene="glyQ"
                     /locus_tag="RH288_004420"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDV4033394.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            complement(3181..3480)
                     /locus_tag="RH288_004421"
     CDS             complement(3181..3480)
                     /locus_tag="RH288_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YsaB family lipoprotein"
                     /protein_id="HDV4033395.1"
                     /translation="MMMNAFFPAMALMVLVGCSIPSPVQKAQRVKVDPLRSLNMEALC
                     KDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR"
     gene            3655..4650
                     /gene="wecH"
                     /locus_tag="RH288_004422"
     CDS             3655..4650
                     /gene="wecH"
                     /locus_tag="RH288_004422"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase WecH"
                     /protein_id="HDV4033396.1"
                     /translation="MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIAN
                     VLNSASRVSVPLFFMISGYLFFGERSAQPRHFLRIGLCLIFYSAIALLYIALFTSINM
                     ELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMAVIGIIANPNTV
                     PQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFII
                     SRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLDTRTIRGLGLISRHSLG
                     IYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSMLVQRIDRNRLVS"
     gene            complement(4692..5129)
                     /locus_tag="RH288_004423"
     CDS             complement(4692..5129)
                     /locus_tag="RH288_004423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiaB family inner membrane protein"
                     /protein_id="HDV4033397.1"
                     /translation="MDNKISTYSPAFSIVSWIALVGGIVTYLLGLWNAEMQLNEKGYY
                     FAVLVLGLFSAASYQKTVRDKYEGIPTTSIYYMTCLTVFIISVALLMVGLWNATLLLS
                     EKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKETQVTQEEYSE"
     gene            complement(5175..5516)
                     /locus_tag="RH288_004424"
     CDS             complement(5175..5516)
                     /locus_tag="RH288_004424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033398.1"
                     /translation="MKTSKTVAKLLFVVGALVYLVGLWISCPLLSGKGYFLGVLMTAT
                     FGNYAYLRAEKLGQLDDFFTHICQLVALITIGLLFIGVLNAPINTYEMVIYPIAFFVC
                     LFGQMRLFRSA"
BASE COUNT         1376 a         1439 c         1365 g         1415 t
ORIGIN      
        1 ataatcttta ttcagcagaa gattattaaa ggttgctgta ttatttagcg ataaaaaaag
       61 cctgccagat ggcaggctat ttaataacgg cgttattatt gcaacagcga aatatccgca
      121 acgcgcagga acagttcgcg cagtttctcc agcatggtca gacggttgat acgcaattct
      181 ttgtcatcaa ccatgaccat cactttatcg aagaaagcat caaccggttc acgcagctca
      241 gccagtgcga ccagcgcatc ctggtaacga ccttccgtaa agtacggctc cagcttgtca
      301 cgtagcacca caacctgcat cgccagttta atttcttccg gctctttcag ggtagaggca
      361 ttcacgcggt cgctcagcac ttcgtcagat ttcgccagaa tgttagatac acgtttgttc
      421 gccgccgcca gtgcagcagc tgcatccagg gtacggaaat gcgataccgc tttcatacgg
      481 gcatcgaaat cagccggacg agtcggacga cgcgccagta ccgcctggat ggtgtcaacg
      541 gtataacctt cgtcctgata ccaggcgcgg aagcgaccga gcataaagtc gataacatca
      601 tcaactacgt tggcattagt cagcttatcg ccatacagac gcaccgcttc ttcggtcagc
      661 gtttgcagat caaggttgag gttcttctca acgataattc gcagcacgcc aagcgcggca
      721 cgacgcagcg caaacgggtc tttgtcgcct ttcggatgct gaccgatacc gaagataccc
      781 gccagggtat ccatcttgtc agcaatcgcc agcgcacaag ctactgggtt ggacggcagg
      841 tcatcaccag caaaacgcgg ctgatactgc tcattcagcg ccaccgcgac atcttccgct
      901 tcgccatcgt gacgcgcata gtgcatcccc ataacgccct gggtgtcggt gaactcgaag
      961 accatgttgg tcatcaggtc gcacttagac agcagacccg cacgggtagc gtggttaacg
     1021 tcagcgccaa tctgttcagc aatccagcca gccagcgcct ggatgcggtc agttttgtcg
     1081 cgcagcgtcc ccaactgttg ctggaacaac acggtttgca ggcgcggcag gttatcttca
     1141 agacgttttt tacggtcggt gttgaagaag aactcggcat ccgccagacg cggacgaacg
     1201 actttctcgt taccggagat aatctgctgc ggatctttcg attcgatgtt ggcaacgaag
     1261 ataaagttcg gcagcagttt gccgtcgttc gcatacaccg ggaagtattt ctggtcacct
     1321 ttcatggtgt aaaccagcgc ttcagccggc accgcgagga atttctcttc gaattttgcg
     1381 gtcagaacga ccggccactc caccagcgaa gccacttctt ccagcaggct ttcgcttaag
     1441 tcagcgttac cgccaatctt acgcgctgct tcttcggcat cggctttaat cttcgcctta
     1501 cgttcttcgt aatcggcgat gactttccca cgctcacgca gaatttccgg atactgatcg
     1561 gcgttatcga tggtgaattc cggctcgccc ataaagcggt ggccgcgaat cacgcgatcg
     1621 gactgaatgc ccagaatggt tgccggaatg actttgtcgc ccagcagcag ggtcacggtg
     1681 tgcaccggac gcacgaagtg cacgtcgctt gcgccccaac gcatcagttt cgggatcggc
     1741 agtttcgcca gagaagtcgc aaccatattc ggcagcagtg cttcggtgct ttcgcccttc
     1801 acatgggcgc gatacagcag ccattcgcct ttatcggtag tcagacgctc agcctggtca
     1861 acggtaatac cgcaaccacg cgcccaacct tctgccgctt tgctcggttt gccttcagcg
     1921 tcgaacgcct gggcaatcgc cgggccgcgt ttttcgattt cacgatccgg ttgcgcttcc
     1981 gccaggttag ctactttcag cgccagacga cgcggagcag caaaccattg aacggtgccg
     2041 tgtgcgaggc cagcgttatc cagctccgca gtaaagttcg cagcaaagga ctcagccagg
     2101 ctgcgcagtg cttttggtgg cagctcttca gtgccgattt ccaccagaaa agttttctca
     2161 gacatagccg cctcttactt atctttgttg cacatcggga agccgagggc ttcacgggaa
     2221 gcgtagtatg cttctgccac tgctttggtc agggtgcgaa tgcgcagaat gtagcgctga
     2281 cgctcggtga cggagatggc tttacgcgca tccagcaggt tgaagctgtg ggcggctttc
     2341 agaatacgct cgtaggctgg cagcggcagc ggattttcca gcgccagcag ctgctgcgct
     2401 tctttctcgt actgctcgaa gcaggtgaac aggaagtcca catccgcgta ttcgaagttg
     2461 taagtggact gctccacttc gttctgatgg aacacgtcgc cgtaggtggt tttacccagc
     2521 gggccgtcgc tccagaccag gtcgtaaacg ctgtctacgc cctgaatgta catggccaga
     2581 cgttccagac cgtaggtgat ctcgccggta accggtttac actccagacc accaacctgc
     2641 tggaagtaag tgaactgcgt cacttccatg ccgttcagcc acacttccca gcccagtccc
     2701 caggcaccca gcgtcgggtt ttcccagtta tcttccacga aacggatgtc gtgaatagtc
     2761 gggtccatgc ccagctcttt cagagaaccg aggtacagct cctgaatatt gtccggcgat
     2821 ggcttaatga ccacctggaa ctgatagtag tgctgtaaac ggttggggtt ttcgccgtag
     2881 cgaccatcgg tcgggcgacg agaaggctga acataagcag ccgccatcgg ttctggcccc
     2941 agcgcgcgca gacaggtcat tgggtgagag gttcccgcgc cgacttccat gtccaatggt
     3001 tgaacaatgg tgcagccctg gcgagcccag taatcctgta aggtcaggat caagccctgg
     3061 aaggtcctgg tatcaaactt ttgcatatta tttcgtgctg gatacgtgtg gatttaaagg
     3121 aagggatcag tatacccgct ggatggaaga tatacagtac gaaacgggaa aaagcagggc
     3181 ttaacgcatg gaaagatgca aaaaatggcc atccgcgtca aaagaacaga caaactgctc
     3241 tttacggaag gtataaccgc gcatttcata gcttccctgg aactgttcga aggcggtgac
     3301 gtcgattttt tgctcgccgg tgttataacg ttttgccgcc tgatccttgc ataacgcttc
     3361 catattcaac gaacgcagag gatcaacctt tacccgttgt gctttctgca cgggtgacgg
     3421 tatagaacaa cccactagca ccataagcgc cattgccgga aagaaagcgt tcatcatcat
     3481 taaattaccg tctggtttgc aggtgagtct tattatttat atcggtatag tggctgatat
     3541 cttacgaatt tccttaagcc tctataagct gtagtgataa aactcagatt attccagtgc
     3601 gccaaccaaa tgatttatcg gtcagacttt ttttaaccag atacagagac acagatgcag
     3661 cccaaaattt actggattga taacctgcga gggatagcgt gtttaatggt ggtgatgatt
     3721 cacaccacta cctggtatgt gaccaatgct catagtgtta gccccgtcac atgggatatc
     3781 gccaatgttc tgaattctgc ctctcgtgtc agcgtgccgc tatttttcat gatttccggc
     3841 tatctctttt ttggcgaacg cagcgcccag ccgcgccatt tcttgcgtat cggcttatgt
     3901 ctgatttttt atagcgcaat cgcactgctc tacattgcgc tgtttacctc catcaatatg
     3961 gagttagcgc tgaaaaacct gctgcaaaag ccagtgtttt accacttgtg gtttttcttc
     4021 gcgattgcgg tgatttatct ggtttcaccg ctgattcagg tgaagaacgt cggcggaaaa
     4081 atgttgctgg tgctaatggc ggtgattggc attatcgcta acccaaacac agtgccgcag
     4141 aaaattgacg gttttgaatg gctgccaatt aacttatata tcaatggcga tactttttac
     4201 tacattctgt atggcatgtt gggccgcgct atagggatga tggacacaca gcataaagca
     4261 ctgtcgtggg tgagcgccgc gctgtttgcg acgggggttt ttattatctc tcgcgggaca
     4321 ttatatgaat tgcagtggcg cggaaatttt gccgatacct ggtatcttta ctgtgggccg
     4381 atggttttta tctgcgcaat cgcgctattg actctggtta aaaacacgct ggatacgcgt
     4441 accattcgcg gacttggctt aatctcccgc cattcattgg gtatatacgg attccacgcc
     4501 ttgattatcc atgcgctgcg cacccgggga attgagctta aaaattggcc aatactggat
     4561 attatttgga tcttttgcgc gacgttggca gcgagtttgt tactttctat gctggtacaa
     4621 cgaatcgaca gaaacagatt agtgagttaa gtaaaagccc ggtcacattg gactgaccgg
     4681 gcttacgtga gttattcgct gtattcttcc tgggtaacct gtgtttcttt tggtgggttt
     4741 attccggcat cacgaatatt tttctgcacc gctactgcac caaacaagct taagaagaaa
     4801 gccagtccat aaaaaccttt ttcgctgagt aataatgtcg cattccacag acctaccatc
     4861 agtaatgcaa cagagataat aaagacagtc aggcaggtca tataataaat ggaagtggtc
     4921 ggtatgcctt catacttgtc ccgaacggtc ttttgataag acgccgcaga aaacagtcct
     4981 aataccagta cggcaaaata atatcctttt tcatttaact gcatctctgc attccatagc
     5041 cctaacagat aggtaacgat accaccaacg agagctatcc atgacacaat actaaaggcc
     5101 ggtgaatagg ttgatatttt gttgtccatc acagtattcc tttcattcct gaatatgtaa
     5161 gagctttatg ttgctcatgc cgagcgaaac aaacgcattt gaccaaacaa gcagacaaaa
     5221 aaggcgatgg gatagatcac catttcataa gtattgatag gtgcgtttaa aacaccgata
     5281 aacaagagac cgatagtgat taacgcaact aactggcaga tatgggtaaa aaaatcatcc
     5341 agttgcccga gtttttctgc gcgaagatat gcatagttgc caaaagttgc tgtcattaac
     5401 acgccaagaa aatagccttt tccacttaac aatgggcatg agatccatag cccaaccaga
     5461 taaaccagcg ccccgacaac aaataatagt tttgccacag tctttgaggt tttcataacg
     5521 atctccatat ctaccagcga tacattacga gtaaccaacg aaagacaaaa ctgaaaaatg
     5581 ccattaacaa atgat
//
LOCUS       DAPHKZ010000206         5580 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.207, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000206 DAPHKZ010000000
VERSION     DAPHKZ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5580
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.207"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            117..1469
                     /locus_tag="RH288_004425"
                     /pseudo
     CDS             117..1469
                     /locus_tag="RH288_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308049.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
     gene            1482..2441
                     /locus_tag="RH288_004426"
     CDS             1482..2441
                     /locus_tag="RH288_004426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial family protein"
                     /protein_id="HDV4033399.1"
                     /translation="MKWLLLITLSLYSFIVQSAPCALTNVGEQRGTYILKPLSMKGNL
                     TAEKIENTGNIIECTDLQETTNAIKVHFLTQNALRFKVGSRHYIINSPFEYDGKKIEL
                     PGKSSYNLEEMLSAINFTIPYSIASVSDSSNTADIFPGTPFPLLFEIEVSSCTGNNTN
                     CNSVRFNYNLNTILQVNLMTCGFEDQSIDTGRFVLSRINNENYQFHHIRFDCIQGEQG
                     ELVFEPSDVEYYFEPVTIQESGTSILKNELENSEDGAGQVGFQLSNDGTNEIQYGKSN
                     YYSFQHPHEGSNQIPLFIRPRTYGNNVSSGQIMSRVKIVVMYN"
     gene            complement(2479..3378)
                     /gene="nhaR"
                     /locus_tag="RH288_004427"
     CDS             complement(2479..3378)
                     /gene="nhaR"
                     /locus_tag="RH288_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705976.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HDV4033400.1"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADA
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSALFSPAAR"
     gene            complement(3444..4610)
                     /gene="nhaA"
                     /locus_tag="RH288_004428"
     CDS             complement(3444..4610)
                     /gene="nhaA"
                     /locus_tag="RH288_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HDV4033401.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAILAMMMANSGATSGWYHDFLET
                     PVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     gene            5196..5348
                     /gene="mokC"
                     /locus_tag="RH288_004429"
     CDS             5196..5348
                     /gene="mokC"
                     /locus_tag="RH288_004429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin MokC"
                     /protein_id="HDV4033402.1"
                     /translation="MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVF
                     TAYESE"
     gene            5426..>5580
                     /locus_tag="RH288_004430"
     CDS             5426..>5580
                     /locus_tag="RH288_004430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HDV4033403.1"
                     /translation="MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLL
                     RLGLAYGP"
BASE COUNT         1690 a         1255 c         1188 g         1447 t
ORIGIN      
        1 ctcactctaa taatggcacc ttgctcttct tataaagaag ggaataatta agaatattaa
       61 actttcatca acttcacatc aagaaattaa aaaatttaaa cattaatcta aataataaca
      121 acctgatcac ataatcgggt acgattttat ccgataacta taatgctata actctgggaa
      181 atggttggaa tacaccgctg ggtgccatct ctttttacgc tgcccgatcg agtagtaagt
      241 taaataatga taccagacac gaaggtacga gctatcaggt cgcctataat aaatatctag
      301 tacaaacagc cactcgattt agcgtggccg cctggcgtta tgcttcgcag gattacagga
      361 cattcagcga ccatctttac gaaaatgata aacactatca tcagagtgat tataatgatt
      421 tttatgatat tggcagaaaa aatagccttt ctgccaatat tatgcaacct ttatccaata
      481 atctgggaaa tgtatcatta agtgcgcttt ggcggaatta ctgggggcga agtggaaatg
      541 ctaaagatta ccaattcagt tactccaata actggcaaca cattagttat actttctctg
      601 ccagccaatc ttatgatgaa aataataaag aagaggagcg ttttaatctg tttatctcca
      661 ttcctttcta ctggggggat gatattgcca aaacacgtca ccaaattaac ttatcgaatt
      721 cgacctcatt ttccaaagat ggctattcct ccaacaatac tggaattact ggcatagccg
      781 gtgaacatga tcagttaaat tatggtatat atgttaatca gcaacaacaa aataatgata
      841 cctcgcttgg tacgaattta agctggagaa ctcccatcgc cataatagat ggcagctata
      901 gtcattctaa aaacgcctgg caaagtggtg gaagtattag tagtggatta gttgtctggt
      961 ccggtggtat taatatcact aaccagttat ccgatacatt tgcaattctg gatgcgcctg
     1021 gattagaagg cgcgcatatt aatggacaaa aatacaaccg aacaaacagc aaaggccagg
     1081 ttgtttacga cccgattata cctcatcgtg aaaaccatct ggtacttgat atagcaaaca
     1141 gtgaaagtga aacagaattg cagggcaatc gtcaaattat tgcgccttac cgtggagcag
     1201 tttcttatgt gcagtttaca actgaccaac gtaagccttg gtatatacag gcactgcgtc
     1261 ccgatggttc gccattaacc tttggctatg acgtactgga tctccaggaa aacaatattg
     1321 gagtcgttgg ccagggtagt cgccttttta ttcgcgtaga tgaaattcca actggcataa
     1381 aagttgctct caatgatgaa cagaatttat tctgtactat tacttttcaa cacgttattg
     1441 atgaaaacaa aacatatata tgccagtaaa aggagtttac tatgaagtgg cttttattaa
     1501 tcaccttgag tctatattct tttattgtgc aaagtgctcc ctgtgcattg accaatgtcg
     1561 gtgaacaacg tggaacatat atactcaagc cactgagtat gaaaggtaat ctcaccgccg
     1621 aaaaaattga aaacaccgga aatatcattg agtgtacaga cttgcaagag acaaccaacg
     1681 ccattaaagt tcatttttta acacagaacg ctttaaggtt taaagtcgga agtcgtcatt
     1741 atattattaa ttcccccttt gaatatgacg gtaaaaaaat agagcttcca gggaagtcat
     1801 cttataattt agaagaaatg ctatctgcga taaatttcac cattccatat tctatcgcat
     1861 ctgtatcaga tagttctaac accgcagaca tttttccagg aactcctttt cctttgttgt
     1921 tcgaaattga agtgagttca tgtacaggga ataatactaa ttgtaatagc gtccgcttta
     1981 attataattt aaatactatt ttacaggtaa atttaatgac ctgtggtttt gaagatcaat
     2041 ccatcgacac tggacgattt gtactgtctc gtatcaataa tgaaaattat cagtttcatc
     2101 atataagatt tgactgcatc cagggcgagc aaggtgaatt agtttttgaa cccagtgatg
     2161 ttgaatatta ctttgaacca gtgacgatac aggagtcagg aaccagcata ttaaaaaatg
     2221 agttagaaaa cagtgaggac ggtgcgggtc aagtaggctt tcaactctcg aatgatggta
     2281 cgaatgaaat ccagtatggt aaaagcaatt actactcttt tcagcatccc catgaaggaa
     2341 gtaatcagat tcctctattt attcgcccgc gtacatatgg aaataatgtc tcaagcgggc
     2401 aaataatgag ccgagtcaaa atcgtggtta tgtacaacta atctatctcc tccactttaa
     2461 ctttggggga gctgccgatt aacgcgccgc tggactaaaa agcgcagaat aatccgtatt
     2521 gcagattcgc tgtaccgccg ggtgctgaat catccgctca gcaaaaatag catggtactc
     2581 ttccatcaca ttctcgacgc gaccaatttc tacgacagtt ttatcggcat aaaagtcata
     2641 tgcataaagc gttggggcaa cgaagattgc attgtgcatt gcaccaaaag ctttcatcaa
     2701 cgcggcatca tcaaactcgc cgaggatttc tacgtttaat ccctgggagt taaaccagtt
     2761 aagcaatttg cgccctaaca ttgaacgtcg cccaggaatc aaaagtcgcc gttcttccag
     2821 acaagccggg aacggttttt ctggtggtgg atttgtacac cagaaactca caccacattc
     2881 gccaattctc acggagaaca ggccttcctg ctgcgtagag tctatcggac agtcggaaat
     2941 gatcatatcc agtttatgct ggcttaattg ctccagtagc atttcgtggg tggattcgaa
     3001 gcagcgaaga tgaatcggct cgccttctac cactgcagca ttcagcacgc tactgaccag
     3061 gcgtttggaa agtgcatcag ccacgccaac gtcaaacaat aaattggatt ctttgcgata
     3121 gttcacaata tccagcattt cctggcttaa ggtgaacatt ttatcggcat agcgatagac
     3181 cagttctccc agctcgctgg gttcgagacc acgtcccttg cgcttaaata atttgccttg
     3241 caggcgctct tccagagccc ggatctgtcc ggtaatggtt tgtggtgtca aataaagcgc
     3301 ctccgctgcg ccaaccacgg aaccttcttt atagacatgc cagaagtaat acaagtggtt
     3361 gtaattgata tgagacatgc tcatttctct ccctgataac aatgaaaagg gagccgttta
     3421 tggctccccg gtaaaccgtc ctgtcaaact gatggacgca aacgaacgcg taaccaactg
     3481 tatccaatta ccgccgaaga gatagaaccg accaggatac cgagtttcgc ccagttaatc
     3541 agttctggat ctacgctacc aaaggccagg ctggcaataa agatagacat agtaaaaccg
     3601 ataccgcaca ggatccccac cgccataatt tgctgataag tcgttccctc aggcagatgc
     3661 gccagtttca aacgcagcgc caaccagcag aacagactaa tccccagcgg tttgccaatc
     3721 agcaagccag cgatgatccc caatggcaga atggaggtca agccatccag cgtgacgcct
     3781 tgcagagaaa cgccagcatt agcgaatgca aacagcggca aaatcagata cgccacccac
     3841 gggtgcaaca catgctccag tcgcttcgct ggagaacgcc catgcttctc tttcaaagga
     3901 ataaagaagc cgacaattac ccccgccaga gttgcgtgaa cccccgattt caacaccgca
     3961 gtccacaaca ctacgccaac cagaatatag acgcccgtgc ggcgtacacc acacagattc
     4021 aataccgcga gtaccgcaat tgctacagcc gcgacgccaa gagaggccat cgataagtca
     4081 ttagtgtaga acaatgcgat gataatgatg gccccaagat cgtcgataat agccagagcc
     4141 atcaaaaaga tcttcagcgc taacggaaca cgacttccca atagcgccag cacaccaagt
     4201 gcaaaggcaa tgtcagtagc cgccgggatc gcccaccctt cgcgggtaat cggatcggca
     4261 tagttaaaag ccagatagag taatgccggc acaatcatcc caccaatagc ggcgataact
     4321 ggaaatgcgg cctggcgtaa gctggctagc gatccttgca tcagttcacg tttaacttcc
     4381 agaccgacta acaggaaaaa taccgccatc agcgcgtcat ttatccataa cagcatgttt
     4441 ttgttgattt cgagtgaacc aacccggagc tgaaccggcg tctccagaaa gtcgtgatac
     4501 catccactgg ttgcgccgct gttggccatc atcatcgcca ggatagcggc aatgataaga
     4561 ataatgcctc ccgaggcatc actgctaaag aatcgatgca gatgtttcac tttttatttc
     4621 tctttcaggt gaatagatcg tttttactat tttaccccgc acgaatcatc gttaaaatca
     4681 gattatagtg taggaataat tcgtttttta cgagccattg aagaatttgc gccatcagcg
     4741 gtgagatgcg tttttgacgg ctgtaagcgc tgacgagtga ccctaagccc tgataatcat
     4801 agcttaaggt gaggatttct gagggattaa ttaggaaaag taataattaa tttgttgtca
     4861 gtcggcgatg tttgttaggc caatatttca aaaataatcc agcttgtcgt caataattgc
     4921 gatgaagaga taaattaaag ttaaataatt aaatcattaa aaaattacgc catcaaaatg
     4981 cgaggcgtct tcaggattag aatcgataaa acagaatgag ttaaagagag cgatataata
     5041 gcggcgggtg cttgaggcta tctgtctcag gcattagctg aacggcagat agagaaaagc
     5101 cccgagtgat attttactat caacccgagg ccccctatat gcagaacaca tgtagagtgc
     5161 ctcttactta ccgtaaggtc aaggagaaga gagcaatgaa gcagcataag gcgatgattg
     5221 tcgccctgat cgtcatctgt atcaccgccg tagtggcggc gctggtaacg agaaaagacc
     5281 tctgtgaggt tcacatccga actggccaga cggaggttgc tgttttcacg gcttacgaat
     5341 ccgagtaaga gcaacggcgg ggagtgatcc cataagcgct aacttaaggg ttgtggtatt
     5401 acgcctgata tgatttaacg tgccgatgaa ttactctcac gataactggt cagcaattct
     5461 ggcccatatt ggtaagcccg aagaactgga tacttcggca cgtaatgccg gggctctaac
     5521 ccgccgccgc gaaattcgtg atgctgcaac tctgctacgt ctggggctgg cttacggccc
//
LOCUS       DAPHKZ010000207         5547 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.208, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000207 DAPHKZ010000000
VERSION     DAPHKZ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5547
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.208"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..838)
                     /gene="yeaE"
                     /locus_tag="RH288_004431"
     CDS             complement(<1..838)
                     /gene="yeaE"
                     /locus_tag="RH288_004431"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal reductase YeaE"
                     /protein_id="HDV4033404.1"
                     /translation="MQQKMIQFSGDVSLPAVGQGTWYMSEDASQRKTEVAALRAGIEL
                     GLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRL
                     NTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
                     CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHA
                     HNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVLEVELSSAELAMLDKAYPAPK
                     GKT"
     gene            complement(928..1674)
                     /gene="mipA"
                     /locus_tag="RH288_004432"
     CDS             complement(928..1674)
                     /gene="mipA"
                     /locus_tag="RH288_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein MipA"
                     /protein_id="HDV4033405.1"
                     /translation="MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDT
                     DVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHL
                     DDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
                     GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTAR
                     YTRLSDEVTDSPMVDKSWTGLISTGITYKF"
     gene            2110..4044
                     /gene="yeaG"
                     /locus_tag="RH288_004433"
     CDS             2110..4044
                     /gene="yeaG"
                     /locus_tag="RH288_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HDV4033406.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLM
                     AIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            4157..5440
                     /locus_tag="RH288_004434"
     CDS             4157..5440
                     /locus_tag="RH288_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HDV4033407.1"
                     /translation="MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQ
                     GQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
                     PANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAE
                     LRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILL
                     YLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNP
                     AQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHL
                     QSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKG"
BASE COUNT         1448 a         1382 c         1351 g         1366 t
ORIGIN      
        1 cagtttttcc ttttggtgcc ggatatgcct tatccagcat agctaattcc gctgaagaaa
       61 gttcgacctc aagcacagcc gcattttgtt ggacatgggc aatcgtggcc gcttttggaa
      121 tcgccatcac accctgatga ctgatcaccc acgccaacaa tacttgtgcc gcgctgatat
      181 tgtgagcatg tgcaatttcg ttgactaccg cgttttttaa cagtccattg cgcaaccgcc
      241 cggcctgggc taacggactg taagccatca ccggcatctg ctgttgctgg caccagggga
      301 gtagatcgta ctcaattcct cgtgaaccga gatggtaaag cacctgatta gtggcacact
      361 gatttccccc cggcagctgc cagagttcct gcatatcagc ataatcaagg ttagaaacgc
      421 cccagcggcg gatttttccc tgggcgatca atttttccat cgctgcgaca gtctcttcaa
      481 aagcgaaact gccagaccag tgtaataagt aaagatcgag ataatcagta ttgagacggc
      541 gtaaactggc ttcgcatgca tttatcgctt tttgcccgcc agcattccac ggatagactt
      601 tagagacgag aaagaccttc tctcgcagac cggttaatgc ttccccaacc accttttcgg
      661 caccgccatc ggcatacatt tcggcggtat caatgagggt taaaccgagt tcaatgcccg
      721 cgcgtagtgc agcaacttct gttttgcgct gactggcatc ttcgctcata taccatgttc
      781 cctgccctac ggctggcagt gagacatcgc cactaaattg aatcattttt tgttgcattg
      841 tttcctccca ggtattgcac caccgtaatg caaaacaggg cgtgacgccc tgtttttatg
      901 cacaaaatgc cctggaaaga tgcattatca gaatttgtag gtgatcccgg tagaaatcag
      961 gccagtccag gatttatcca ccatcgggct gtcagtaact tcatcagaca gacgggtgta
     1021 gcgtgcggta ccgtaaacac tccagtcgcc gaggaagttg tagctggcgc tcagctccag
     1081 gtaagggctc cagctgtcgt tcgggttata gccacgcaga ccgctgcgag cggactcttt
     1141 gcgcgatacg ccataatagt attcgttctg gttttcgctg ttccactgca caccaatacc
     1201 cggagtcacg gtcaggccac cgttggtgta acgatacaac caggccatat cccagacgat
     1261 gccgttgctg ttatccaggg tatcgccagc cagggtggta cgcaggtaac cgtactgggt
     1321 aaagtgagca taagacagac cagccatcat ggtgctctta cggtcatcca ggtgacgcat
     1381 ttggtgatcg ccactgtctt tcgctttgaa gtaaagcggc gaccagtaag cggtaattga
     1441 aagtttatcc gttgcgtcat tccacaggta gtaaccacca cctaagccac ggaaccagaa
     1501 gttatcgcct tcatagttga ttaccggtac tgggtaaaca tcggtatcgt aatctttata
     1561 tgggtgttca acgacaccta cgcctgcgcc cagggaaaat ttaccttcag cgtgcgctac
     1621 gcctgcagac gttgcgataa gcactccaag tgccagaagt ttgagtttgg tcacaattaa
     1681 tcattcctta aacaaatgtt tagcgggcga caaagtttac ccgtcaatac atcgaaaccc
     1741 aaccttttta cgttttcatt ttttaaagta actgtttaat tttcctgacg cggatgacac
     1801 cgcgcttaca gccaaatgaa tttagcgtta ctggcgagcc tggtctttac attaattatg
     1861 caaaatttat ggatgagttg ttgatatgcc attgaaatta agaaagccgt gcaggcaagt
     1921 tttccatttg ccatctacgc ttaattttga aggtgtatca ccgggcacgt tgttctcatc
     1981 gtcgataaaa tggcatgaga gttgctgtgt tttagcaaga gacgtcgttc agtttacctc
     2041 ttccgggagc ctctactatt catatgaacg gctcttaacc tgtgctaaaa aacgaaagga
     2101 cggcatacca tgaatatatt cgatcactat cgccagcgat atgaagctgc caaggacgaa
     2161 gagttcacac tgcaggagtt tcttaccact tgtcggcaag atcgcagtgc ttatgccaac
     2221 gcggctgagc ggctattgat ggctatcggt gagcctgtca tggtcgatac agcccaggaa
     2281 cccagacttt ctcgactctt ttctaaccgg gtcattgcac gttatccggc gtttgaagag
     2341 ttttacggca tggaagacgc gattgaacag attgtctctt atctgaaaca cgcggctcag
     2401 gggctggaag agaagaaaca aatcctgtat ctgctggggc ctgtgggtgg gggtaaatca
     2461 tcgcttgctg agcgactgaa atcattaatg cagctcgtac cgatttatgt attgagcgcc
     2521 aacggtgagc gtagcccggt caacgatcat ccgttctgtc ttttcaatcc gcaggaagat
     2581 gcgcagattc tggaaaaaga gtatggcatt cctcgccgtt atctcggcac catcatgtcg
     2641 ccgtgggcgg caaaacgcct gcatgaattt ggtggcgata tcactaagtt ccgggtagtg
     2701 aaggtctggc cgtcaattct gcaacaaatt gctatcgcca aaacggaacc cggcgatgag
     2761 aacaaccagg acatctccgc gctggttggg aaagtcgata ttcgtaaact cgaacactac
     2821 gcgcagaatg acccggacgc ctacggctat tccggtgcgc tgtgccgcgc caatcagggg
     2881 atcatggaat tcgttgagat gtttaaagca ccgattaaag tgctgcatcc cttgttaacc
     2941 gccactcagg aaggtaacta caacgggacg gaaggtatct ccgccctgcc gttcaacggg
     3001 attattctcg cacactcgaa cgagtccgaa tgggtcactt tccgtaataa caaaaacaac
     3061 gaagccttcc tcgatcgtgt ttacatcgtg aaggtgccgt attgcttgcg catttccgaa
     3121 gagatcaaaa tctacgagaa attgcttaat cacagtgaat tgactcacgc cccatgcgcc
     3181 cctggcacgc tcgaaacact gtcacgtttt tccattcttt cgcgcctgaa agagccagaa
     3241 aactccagca tttattcaaa gatgcgggtt tatgatggcg aaagtctgaa agacaccgat
     3301 cccaaagcca agtcgtatca ggaatatcgt gactacgccg gtgtcgatga agggatgaac
     3361 ggtctgtcga cgcgttttgc gtttaagatc ctctcccgcg tgttcaactt cgatcatgta
     3421 gaagtggcag caaacccggt ccatctgttc tacgtcctgg aacagcagat tgagcgcgag
     3481 cagttcccac aagagcaggc agaacgctat ctggagttcc tgaaaggtta tctgatcccg
     3541 aaatatgccg agtttatcgg caaagagatc cagacggcct accttgaatc ctattccgaa
     3601 tatgggcaaa acattttcga ccgttatgtt acctacgcgg atttctggat tcaggatcag
     3661 gagtatcgcg atccggatac cgggcagctg tttgaccgcg agtctcttaa cgccgagctg
     3721 gagaaaatcg agaaaccggc ggggatcagt aatccaaaag atttccgcaa cgagattgtt
     3781 aacttcgtac tgcgcgccag agcgaataac agcggacgca atccgaactg gaccagctat
     3841 gaaaaactgc gcacggtcat cgagaagaaa atgttctcca ataccgagga gctgttgccg
     3901 gttatctcgt ttaacgccaa aacgtcaacc gacgagcaga agaaacacga cgactttgtc
     3961 gaccgtatga tggaaaaagg ctacacccgt aaacaggtgc gtttactgtg cgaatggtat
     4021 ttgcgcgtac gtaaatcgtc ttaacaaccc tggcccggta cacatgttac cgggcctaca
     4081 acgacagcga accgtgggcc tgagaagcgg caacacaggc gtagcataca gttggcaaat
     4141 gtagtacggg gggcatatga cctggtttat tgaccggcgt ctgaacggca aaaacaaaag
     4201 catggtgaat cgccagcgtt ttttacgccg ttataaagcg caaattaaac agtcgatctc
     4261 cgaggccatt aataagcgtt cggtgactga cgtcgacagc ggcgaatccg tatccattcc
     4321 cacggaagat attagcgaac cgatgtttca tcaggggcgt ggcggtctgc gccaccgcgt
     4381 gcatccgggc aatgaccatt tcgtccagaa cgaccgaatt gaacgtcccc agggtggcgg
     4441 cggaggttcc ggcagtggtc agggccaggc cagccaggat ggtgaaggtc aggatgaatt
     4501 tgtctttcag atttcgaaag atgagtatct tgatctgctc tttgaagatt tggccttacc
     4561 gaatctgaaa caaaaccaac aacgccagct gaccgaatat aaaacgcatc gggcgggtta
     4621 taccgctaac ggcgttccgg ccaatatcag cgttgtgcgt tcattgcaga actcactggc
     4681 gcgacgcaca gccatgacgg caggcaagcg gcgggaactt catgcactgg aagagaattt
     4741 ggccatcatc agcaacagtg aacctgcgca actgctggaa gaggaacgtc tgcgcaaaga
     4801 aattgcagaa ttacgtgcca aaattgaacg cgtccctttt attgacacct tcgatttacg
     4861 ttacaagaac tacgagaagc ggcccgatcc ctccagccag gcagtgatgt tttgcctgat
     4921 ggacgtttcc ggttcaatgg atcaatccac taaagatatg gctaagcgtt tttatattct
     4981 gctgtatctg ttcctcagca gaacgtataa gaacgtggaa gtcgtataca tccgccatca
     5041 tacccaggcg aaagaagtcg atgaacatga gtttttctac tcgcaggaaa caggcggcac
     5101 cattgtttcc agcgccctga aactgatgga tgaggtagtg aaagagcgtt ataacccggc
     5161 acagtggaat atttacgctg cacaagcatc ggacggcgat aactgggccg atgactctcc
     5221 gctttgccat gaaatcctgg cgaaaaaatt attacctgtt gttcgttatt acagctatat
     5281 cgaaattacc cgtcgtgcac atcagacatt gtggcgagaa tatgagcatc tgcaatctac
     5341 tttcgacaac tttgcgatgc agcacatccg cgaccaggat gatatttatc cggtgttccg
     5401 tgaactgttt cataaacaaa atgcaacagc taaaggctaa aactatcagc caggtcatta
     5461 tcgcctggct gatttttagc ttactgtaaa ttatctcatt tattacatac attagcttac
     5521 aatcgcttta aatatgacag cataacc
//
LOCUS       DAPHKZ010000208         5426 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.209, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000208 DAPHKZ010000000
VERSION     DAPHKZ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5426
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.209"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            198..1256
                     /gene="citC"
                     /locus_tag="RH288_004435"
     CDS             198..1256
                     /gene="citC"
                     /locus_tag="RH288_004435"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415151.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HDV4033408.1"
                     /translation="MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTR
                     DEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYE
                     ALFRQCGFSTLTSVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIVMNANPFTNG
                     HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISR
                     ATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMR
                     YWLETPTISAPPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQ
                     NLLEHSRQDAAARQKTPA"
     gene            1271..1567
                     /gene="citD"
                     /locus_tag="RH288_004436"
     CDS             1271..1567
                     /gene="citD"
                     /locus_tag="RH288_004436"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HDV4033409.1"
                     /translation="MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDA
                     IRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ"
     gene            1564..2472
                     /gene="citE"
                     /locus_tag="RH288_004437"
     CDS             1564..2472
                     /gene="citE"
                     /locus_tag="RH288_004437"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HDV4033410.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE
                     DSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNG
                     KMVDGPVIDRARLVLSRAELSGIREE"
     gene            2483..4015
                     /gene="citF"
                     /locus_tag="RH288_004438"
     CDS             2483..4015
                     /gene="citF"
                     /locus_tag="RH288_004438"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HDV4033411.1"
                     /translation="MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDR
                     KLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSD
                     CHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
                     DVAFLGVPSCDEFGNANGYTGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASI
                     EQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQT
                     GTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSHAA
                     QSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRG
                     ASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPAR
                     PELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQV
                     KE"
     gene            4019..4570
                     /gene="citX"
                     /locus_tag="RH288_004439"
     CDS             4019..4570
                     /gene="citX"
                     /locus_tag="RH288_004439"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HDV4033412.1"
                     /translation="MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFT
                     VVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPAR
                     DLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKT
                     HQLTDLLNRMEALLNDVDACNVN"
     gene            4545..5423
                     /gene="citG"
                     /locus_tag="RH288_004440"
     CDS             4545..5423
                     /gene="citG"
                     /locus_tag="RH288_004440"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HDV4033413.1"
                     /translation="MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDR
                     INCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDM
                     FRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
                     NSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLL
                     LMAINGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSP
                     GGSADLLILTWFLAQI"
BASE COUNT         1256 a         1536 c         1429 g         1205 t
ORIGIN      
        1 aaaaaccact aactctatgt gaaataaatc aaaatttcac gccgaaatac tccttaggat
       61 gtatagcgaa aggagaaaaa gatatacctc gatcaccccc tttctcccaa gtgaaaataa
      121 aaggttatca gtttgcaaca ttgaacaaca ttcgttgcaa atcgataaca acatgcacct
      181 tcaggatact atttattatg ttcggcaatg atattttcac ccgcgtaaaa cgttcagaaa
      241 ataaaaaaat ggcggaaatc gcccaattcc tgcatgaaaa tgatttgagc gttgacacca
      301 cagtcgaagt atttattacc gtaacccgcg atgaaaagct tatcgcgtgc ggtggaattg
      361 ccggaaatat tattaaatgc gttgctatca gtgaatccgt ccgcggtgaa ggactggcgc
      421 tgacattagc cactgaattg ataaacctcg cctatgagcg gcacagcacg catctgttta
      481 tttataccaa aaccgaatac gaggcgctgt tccgccagtg cggtttttcc acgctgacca
      541 gcgtacccgg cgtgatggtg ctgatggaaa acagcgccac gcgactgaaa cgctatgccg
      601 aatcgctgaa aaaatttcgt catccaggga acaagattgg ctgcattgtg atgaacgcca
      661 atccctttac gaatggtcac cgttatctga ttcaacaggc tgcggcacag tgcgactggt
      721 tgcatctgtt tttagtcaaa gaagattctt cacgcttccc ctatgaagac cggctggatt
      781 tggtgttaaa aggcaccgcc gatattccac gcctgactgt gcatcgtggc tccgaataca
      841 tcatctcccg cgctacgttc ccttgctact tcattaaaga acagagcgtc attaaccatt
      901 gttacaccga aattgatctg aagattttcc gtcagtacct cgctcccgcg ctgggtgtaa
      961 ctcaccgctt tgtcggtact gaaccctttt gtcgcgttac cgcccagtac aaccaggata
     1021 tgcgctactg gctggaaacg ccgactatct ccgcaccgcc catcgaactg gttgaaattg
     1081 agcggctgcg ttaccaggag atgccgatat ccgcttcccg ggtacgtcaa ctgctggcga
     1141 aaaacgatct cacggctatc gcgccgctgg tccctgcagt cacgctgcat tatttgcaga
     1201 acctgcttga gcactcccgc caggacgcgg cagctcgtca aaagaccccc gcatgagaaa
     1261 caggtgaaaa atgaaaataa accagcccgc cgttgcaggc acccttgagt ctggggatgt
     1321 gatgatacgc atcgccccac tcgatacgca ggatatcgac ctgcaaatca atagcagcgt
     1381 tgagaaacag tttggcgatg caattcgcac caccattctg gacgttctcg cccgctacaa
     1441 cgtgcgcggc gtacagctga atgtcgatga caaaggcgca ctggactgca ttttacgtgc
     1501 acgactggaa gccctgctgg cacgcgccag cggtatcccg gctctgccat gggaggattg
     1561 ccaatgattt ccgcttcgct gcaacaacgt aaaactcgca cccgccgcag catgttgttt
     1621 gtgcctggtg ccaatgccgc gatggtcagc aactccttca tctacccggc tgatgccctg
     1681 atgtttgacc tcgaagactc cgtagcattg cgtgaaaaag acaccgcccg ccgcatggtt
     1741 taccacgcgc tgcaacatcc gctgtatcgc gatattgaaa ccattgtgcg tgtcaacgcg
     1801 ctggattccg aatggggtgt taacgacctg gaagccgtcg ttcgcggtgg tgcggacgtt
     1861 gtgcgtctgc cgaaaaccga taccgctcag gatgttctgg atattgaaaa agagatcctg
     1921 cgtatcgaaa aagcctgtgg tcgtgaaccc ggcagcaccg gcctgctggc ggcgattgaa
     1981 tctccgctgg ggattacccg cgcagtggaa atcgctcacg cttccgagcg tttgatcggt
     2041 atcgccctcg gtgcagaaga ctatgtgcgc aacctgcgta cagaacgctc cccggaagga
     2101 actgaactgc tgttcgcacg ctgttccatt ttgcaggccg cgcgctctgc gggtattcag
     2161 gcgttcgata ccgtctattc cgacgctaac aacgaagccg gatttctgca agaagccgcc
     2221 cacatcaaac agctgggctt tgacggcaaa tcgctgatca acccgcgtca gattgatctg
     2281 ctgcacaacc tctacgcacc gacccagaaa gaagtggatc acgcccgccg cgtcgtagaa
     2341 gccgctgaag ccgccgctcg cgaaggcctc ggcgtggttt ccctgaacgg caagatggtg
     2401 gacggtccgg ttatcgatcg cgcccgtctg gtgctctccc gtgcagaact ttccggcatc
     2461 cgcgaagaat aaggcaatca aaatgacgca gaaaattgaa caatctcaac gacaagaacg
     2521 ggtagcggcc tggaatcgtc gcgctgaatg cgatcttgcc gctttccaga actcgccaaa
     2581 gcaaacctac caggctgaaa aagcgcgcga tcgcaaactg tgcgccaacc tggaagaagc
     2641 gattcgtcgc tctggtttac aggacggcat gacggtttcc ttccatcacg ctttccgtgg
     2701 cggtgacctg accgtcaata tggtgatgga cgtcatcgcg aagatgggct ttaaaaacct
     2761 gaccctggcg tccagctccc tgagtgattg ccatgcgccg ctggtagaac acattcgcca
     2821 gggcgtggtt acccgcattt atacctccgg cctgcgtggt ccactggcgg aagagatctc
     2881 ccgtggtctg ctggcagaac cggtgcagat ccactctcac ggcggtcgtg tgcatctggt
     2941 acagagcggc gaactgaata tcgacgtggc tttcctcggc gtcccgtcct gtgatgaatt
     3001 cggtaatgcc aacggctaca ccggtaaagc ctgctgcggc tccctcggct atgcaatggt
     3061 tgatgccgac aacgcaaaac aggtcgtgat gcttaccgaa gaactgctgc cttatccgca
     3121 taatccggca agcattgagc aagatcaggt tgatttgatc gtcaaagttg accgcgttgg
     3181 cgatgctgca aaaatcggcg ctggcgcgac ccgtatgacc actaacccgc gcgaactgct
     3241 tattgcccgt agcgctgcgg atgtgattgt caactctggc tacttcaaag aaggtttctc
     3301 catgcaaacc ggcaccggcg gcgcatcgct ggcggtaacc cgtttcctgg aagacaaaat
     3361 gcgtagccgc gatattcgcg ccgacttcgc ccttggcggt attaccgcga cgatggttga
     3421 cctgcacgaa aaaggtctga tccgcaaact gctggatgtg cagagctttg acagccatgc
     3481 tgcgcaatcg ctggcccgta accccaatca catcgaaatc agcgccaacc agtacgctaa
     3541 ctggggttcg aaaggcgcat cggttgatcg tctcgacgtg gtggtactga gcgcgctgga
     3601 aattgacacc cagttcaacg ttaacgtgct gaccggctct gacggcgtac tgcgtggtgc
     3661 ttccggtggt cactgcgata ccgcgattgc ctctgcgctt tccatcatcg tcgcgccgct
     3721 ggtacgcggt cgtattccga ctctggtgga taacgtactg acctgcatca ccccaggctc
     3781 cagtgtcgat attctggtca cagaccacgg tatcgcagtt aacccggcac gtccggaact
     3841 ggcagaacgt ctgcaggaag cgggcattaa agtggtttcc attgagtggc tgcgcgaacg
     3901 tgcgcgtctg ctgaccggtg aaccacagcc gattgaattc acagaccgcg tcgttgccgt
     3961 tgtgcgttac cgcgatggct cggtgatcga tgttgtgcat caggtgaagg aataagccat
     4021 gcacctgctt cctgaactcg ccagccacca tgcggtatca attcccgagc tgctcgtcag
     4081 ccgggatgaa aggcaagcac ggcaacacgt ctggctcaag cgccatcctg ttccactggt
     4141 ctcctttacc gtggttgcgc ctgggccgat taaagacagc gaggtcacac gccgaatttt
     4201 taatcatggc gtgacagcct tgcgtgcctt agccgcaaaa cagggctggc aaattcagga
     4261 gcaggctgca ctggtttccg ccagcgggcc ggagggcatg ttgagcattg ccgccccggc
     4321 tcgcgacctc aagctcgcca ccattgagct tgaacatagt catcctctcg ggcggttatg
     4381 ggatatcgat gtcctgacgc ccgaaggcga aattctctcc cgccgcgact attcactgcc
     4441 gcctcgccgc tgcctgttgt gcgagcaaag cgcagccgtc tgcgcgcgtg gaaaaaccca
     4501 tcaactgacc gatttactca accgcatgga ggcactgctg aacgatgtcg atgcctgcaa
     4561 cgtcaactaa aaccacaaag cttgcgacgt cattaatcga tgagtacgcc ctgctgggct
     4621 ggcgcgccat gctgactgaa gtcaatctgt caccgaaacc aggcctcgtg gatcgcatta
     4681 actgcggtgc gcacaaagat atggcgctgg aagatttcca ccgcagcgcg ctggcgattc
     4741 agggctggct accccgtttc attgaatttg gtgcctgtag tgcggaaatg gcaccagaag
     4801 cggtactcca cggattacgc ccaattggta tggcttgcga aggtgatatg ttccgcgcca
     4861 ctgcgggcgt aaacacgcat aaaggcagca ttttttcttt agggctgcta tgtgcggcaa
     4921 ttggccgttt gcttcaactc aaccaaccgg taacgccaac aaccgtttgt tctacggcgg
     4981 caagtttctg ccgtggcctg accgatcgcg aactgcgtac caataattca caactgacgg
     5041 caggtcaacg gttgtaccaa cagcttggcc ttaccggcgc acgcggtgaa gccgaagcgg
     5101 gttatccact ggtgatcaat cacgccttgc cgcattacct cactctgctg gatcaggggt
     5161 tagatcctga actggcattg ctcgatacct tgctcctact gatggcgatc aacggcgata
     5221 ccaacgttgc atcgcgcggt ggcgaggggg gcctgcgctg gctacagcgc gaggcgcaaa
     5281 cattattgca aaaagggggc attcgaaccc ccgccgatct cgattatctc cggcagttcg
     5341 acagggagtg tatcgaacga aatctcagtc caggcggcag tgctgaccta ctgatcctta
     5401 cctggttttt agcacagatt taatta
//
LOCUS       DAPHKZ010000209         5325 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.210, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000209 DAPHKZ010000000
VERSION     DAPHKZ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.210"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..473)
                     /locus_tag="RH288_004441"
     CDS             complement(<1..473)
                     /locus_tag="RH288_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4033414.1"
                     /translation="MAIKGLEQAVENLSRISRTAVPGAAAMAINRVASSAISQSVAQV
                     ARETKVRRKLVKERARLKRATVKNPQARIRVNRGDLPVIRLGNARVVLSRRRRRKKGQ
                     RSSLKGGGSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAEPL"
     gene            complement(485..838)
                     /locus_tag="RH288_004442"
     CDS             complement(485..838)
                     /locus_tag="RH288_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HDV4033415.1"
                     /translation="MADFDNLFDAAIARADETIRGYMGTSATMTSGEQSGAVIRGVFD
                     DPENISYAGQGVRVEGSSPSLFVRTDDVRQLRRGDTLTIGEENFWIDRISPDDGGSCH
                     LWLGRGVPPAVNRRR"
     gene            complement(850..1245)
                     /locus_tag="RH288_004443"
     CDS             complement(850..1245)
                     /locus_tag="RH288_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HDV4033416.1"
                     /translation="MTKDELIARLRSLGEQLNRDVSLTGTKEELALRVAELEEELDDK
                     DDAAGQDTSVSPENALTGHENEVVSAQTDTVTDTAVLVTVVALVTLHTDALHATRDEA
                     VAFVLPGTAFRVSAGVAAEMTARGLARMQ"
     gene            complement(1287..2312)
                     /locus_tag="RH288_004444"
     CDS             complement(1287..2312)
                     /locus_tag="RH288_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HDV4033417.1"
                     /translation="MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQI
                     PGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLA
                     DPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSEEN
                     NITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVREKL
                     DTRRGSHSELETAVKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGN
                     TQARGLRTYGCIQDADAQREGINASARYPKNWVTSGDPAREFTMIQSAPLMLLADPDE
                     FVSVQLA"
     gene            complement(2368..2700)
                     /locus_tag="RH288_004445"
     CDS             complement(2368..2700)
                     /locus_tag="RH288_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HDV4033418.1"
                     /translation="MTSKETFTHYQPLGNSDPAHTATAPGGLSAKAPAMTPLMLDSST
                     RKLVVWDGTTDGAAVGILAVAADQTSTKLTFYKSGTFRYEDVLWPEDASDETKKRTAF
                     AGTAISIV"
     gene            complement(2710..4029)
                     /locus_tag="RH288_004446"
     CDS             complement(2710..4029)
                     /locus_tag="RH288_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HDV4033419.1"
                     /translation="MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLT
                     DAVSGDSLTAGEAPATLALSGNDDGPRQARSYQVMNGIAVLPVSGTLVSRTRALQPYS
                     GMTGYNSIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
                     NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHK
                     VDGNPYSHLPDDVRETLQSRMDATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAID
                     AGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSATASQADITSMEPAK
                     EGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVETAR
                     RILAAAPQSAQARSDTALDRLMQGAPAPLAAGNPASDAVNDLLNTPV"
     gene            complement(4010..>5325)
                     /locus_tag="RH288_004447"
     CDS             complement(4010..>5325)
                     /locus_tag="RH288_004447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV4033420.1"
                     /translation="LGIGEEEARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIRE
                     GVAMHAFNGELFVQATWDTSPSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDS
                     GAALGYYVSEDGYPGWMPQKWTWIPRELPGGRASFIHVFEPVEDGQTRGANVFYSVME
                     QMKMLDTLQNTQLQSAIVKAMYAATIESELDTQSAMDFILGANSQEQRERLTGWIGEI
                     AAYYAAAPVRLGGAKVPHLMPGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQ
                     LSRNYAQMSYSTARASANESWAHFMGRRKFVASRQASQMFLCWLEEAIVRRVVTLPSK
                     ARFSFQEARSAWGNCDWIGSGRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQE
                     IFAQQVRETMERREAGLKPPAWAAAAFESGLRQSTEEEKSDSRAA"
BASE COUNT         1049 a         1684 c         1427 g         1165 t
ORIGIN      
        1 agcggctccg ccatcgggat tttcaccaca tcaatggggt aacggttttt cccggccaca
       61 cgctgcatga catgccaccg gccatttttc agttgctgaa taaacgcgcc gggaatacga
      121 cggtttccca ccacaagcac gctgccgcca cctttcaggg atgaacgctg ccccttttta
      181 cgacgtctgc ggcgggaaag gacaacccgc gcgttaccca gcctgattac gggcaaatcc
      241 ccccggttaa ccctgattct ggcctgcgga tttttgaccg tggccctttt cagcctggcc
      301 ctttccttta ccagtttccg gcgtaccttt gtctcacggg caacctgtgc caccgactgc
      361 gatatcgcgg atgaagcaac gcggttaatg gccattgcgg cggcaccggg caccgccgtt
      421 ctgctgatac ggctgaggtt ttcaacggcc tgctcaagac cttttatggc catacatccc
      481 cctttcagcg gcgacggtta acggcaggcg gtacgccccg cccaagccag agatgacagc
      541 tcccgccatc atccggcgaa atccggtcta tccagaagtt ttcctcaccg atggtcagcg
      601 tgtcgccgcg ccgcagctgc cgcacatcat cagtccggac aaacagggac gggctggagc
      661 cttcaacgcg cacgccctgt ccggcatagc tgatattttc agggtcatca aaaacaccac
      721 gtattactgc gccggactgc tcaccggatg tcatggtggc tgacgttccc atgtacccgc
      781 gtatcgtttc atcggcgcgg gcaatggcag catcgaacag gttatcgaaa tcagccacag
      841 cgcctcccgt tattgcattc tggccaggcc gcgcgctgtc atttcagctg ccacaccggc
      901 agagacacgg aacgccgttc ccggcagcac aaatgccaca gcctcatccc gcgtggcgtg
      961 aagtgcatcg gtatgcagcg tcaccagtgc cacaaccgtg accagaacag ccgtatcagt
     1021 cacggtatcc gtctgtgctg ataccacctc attttcatgt ccggtcagcg cattttccgg
     1081 gctgacagac gtgtcctgac cggctgcgtc atccttgtca tcaagctcct cttccagctc
     1141 tgccacacgg agcgccagtt cttctttcgt ccccgtcagg ctgacatcac ggttcagttg
     1201 ctcacccagc gaccggagac gggcaatcag ttcatctttc gtcatggact cctccacaga
     1261 gagaaaatgg ccccgaaggg ccatgattac gccagttgaa cggacacgaa ctcatcagga
     1321 tcagccagca gcatcagcgg tgctgactga atcatggtga actcacgcgc cggatcgccg
     1381 ctggtcaccc agtttttcgg gtagcgggca gaagcgttaa taccttcgcg ctgtgcgtcc
     1441 gcatcctgaa tgcagccata ggtgcgcaga ccgcgagcct gagtgttacc cagcaccatc
     1501 gtgttgtccg gcagaaagtt ctttttgacg ccgttttcca cgtactgtcc ggaatacacg
     1561 acgatggcca catcgccata catcccctta taggacaccg ctttacccag gtctttcacc
     1621 gctgtctcca gctcggaatg agagccacga cgggtatcca gcttctccct gacggctttg
     1681 aaggaacgga acagcgccca gcctttcgga tcgaacacga tgatattcac cacaccgctg
     1741 gcgttcagcg cgtaggcttc gatatcgtcg gtcgggtcat acgtggactt gtcacgcttg
     1801 ctccactccg tgccgccgga ctgcgtgatg ttattctcct cactgcggcc catatccacc
     1861 tcaaccggat cgaaggcttc accggtcatg gtgtatttgc ccttaagcac ggcagaaact
     1921 gcctgcatct cttcgacctg agcaatggcc agctcttcgt cacgcatgtt ctgcatgatg
     1981 atgcgacggc ggcggtaagc cgggtccgcc agattctgcg gatcttcatc cggcaggcga
     2041 cgcagggtca tctgcggatt cacttcatgc ttcggcttga catatcccgg cgtaaattca
     2101 gaggtggagc cgccacggga acggataacc tcaccggaaa caatcggcga aacgtacagc
     2161 gccatgttta ccagtcccgg aatttgtgag agatagactt tctccgtggt gaagggatag
     2221 ctctcacgga aaaagagacg cagaaacagc ggatcaaact taaatttctg ctcatttgcc
     2281 gccagcagct gggcggttgt gtacatcgac ataaaaaaat cccgtaaaaa aagccgcaca
     2341 ggcggccttt agtgatgaag ggtaaagtta aacgatgctg attgccgttc cggcaaacgc
     2401 ggtccgtttt ttcgtctcgt cgctggcatc ctccggccag agcacatcct cataacggaa
     2461 cgtgccggac ttgtagaacg tcagcttggt gctggtctgg tcagcagcaa ccgccagaat
     2521 gccaacggca gcaccgtcgg tggtgccatc ccacacaacc agcttacggg tggagctatc
     2581 cagcatcagc ggggtcattg caggcgcttt cgcactcaat ccgccaggcg cggttgccgt
     2641 atgtgccggg tcactgttgc ccagcggctg gtaatgggta aaggtttctt tgctcgtcat
     2701 aaacatccct tacactggtg tgttcagcaa atcgttaacg gcatcagatg ccgggttacc
     2761 tgcagccagc ggtgccggtg ccccctgcat cagacgatcc agcgcagtgt cactgcgcgc
     2821 ctgtgcactc tgtggtgctg cggccagaat gcggcgggcc gtttccacgg tcataccggg
     2881 ggtttctgcc agcacgcggg cctgttcttc gcgtccgtga gcctcctcac aattgaggat
     2941 ccccataatg cggctgtttt ctgccgcaac cgctgcggtg atctgcgcgt tcacgtccgg
     3001 ctgcgccgcg gatgcgttct cgccctcctt cgctggctcc atgctggtga tgtcagcctg
     3061 cgaagcagtg gctgaaacag ttgttgattg agtctctttg gtcattcgcc ctcctgagag
     3121 tcgggattta cgtgcatcca gtgcatcacg catgacggtg atcgcatcgg tgctgttgac
     3181 aagttcatca gccagtccgg catcaatggc ctcctgaccg ctgtacactg cagcctcggt
     3241 atccagcaca gcctgcacgg acaggccggt atatgccgac accttctgtg caaacatccg
     3301 gcgggttgca tccatccggg actgcagtgt ttcccggacg tcatctggta gatggctgta
     3361 ggggttgcca tccaccttat ggctgccgct gtaaatcagc gtgatttcca cgccctgttt
     3421 ctccagcgca gcgccgtaat tactgtgagc catcatgacg ccgatggagc ctgtccgggc
     3481 ggtctgcgtg accagacgcc gggaggcggc gctggcaagc agctgacctg cactgcagtt
     3541 catgtcgttg gccagcgccc ataccggttt tatgtcacgc acacgggcaa tgatgtcagc
     3601 gcagtcaaat gcccccgcca ccatcccgcc tggcgtgtcc atatcgagca gaatgccgtc
     3661 caccatcggg tcgctggcag cctgttgcag acgggcgata atgctgttgt aaccggtcat
     3721 ccccgaatac ggctgcagcg cccgcgtccg gctgaccagc gtgccggaca ccggcagcac
     3781 ggcgatgccg ttcatgacct gataactgcg ggcctgtcgt ggcccgtcat cattaccgga
     3841 taacgccagc gtcgcgggtg cctctccggc agtcaggctg tcaccggaca ccgcatccgt
     3901 caggcggctg atccccagct ggcctgcaag cgcacaaaag aaaacccgcg cataggcggg
     3961 ttcaagcatc agcggctcat taaaagccat actggcaata tgcgggagat tacgcagctc
     4021 tgctgtcact cttctcctcc tctgttgatt gtcgcagccc ggattcaaat gccgctgccg
     4081 cccaggcggg cggtttaaga ccggcttcgc ggcgctccat cgtttcacgg acctgctggg
     4141 caaaaatttc ctgatagtcg tcgccgcgtt ttgcgcactc tttctcgtag gtgctcagtc
     4201 cggcttctat cagcatcacc gcttcctgta cttctttcag accatcgata gccatacgac
     4261 cggagcctat ccagtcacag ttcccccagg cgctgcgggc ttcctgaaag ctgaagcgcg
     4321 cttttgaagg taacgtcacc acgcggcgaa cgatggcctc ttccagccag cacagaaaca
     4381 tctggctcgc ctgacgggat gcgacgaatt ttcgccgccc cataaagtgc gcccacgact
     4441 cgttcgcgct ggcccgtgcc gtggagtagc tcatctgggc gtaattccgg gaaagctgct
     4501 catacgagac acccagcccg gcagcgatat accgcagcag tgactgctca aacacggagt
     4561 agccgttatc cgtgtcctga gccgtctgca ggttcagtga gtcccccggc atcaggtgcg
     4621 gcacttttgc gcctcccaga cggaccggtg ctgcggcgta atacgcggca atttcaccaa
     4681 tccagcccgt cagcctttcc cgctgctcct gactgttcgc gcccagaata aaatccatcg
     4741 ctgactgcgt atccagctca ctttcaatgg tggcggcata catcgccttc acaatggcgc
     4801 tctgcagctg cgtgttctgc agcgtgtcga gcatcttcat ctgctccatt acgctgtaaa
     4861 acacatttgc accgcgggtc tgcccgtcct ccacgggttc aaaaacgtga atgaacgagg
     4921 cgcgcccgcc gggtaactca cggggtatcc atgtccattt ctgcggcatc cagccaggat
     4981 agccgtcctc gctgacgtaa tatcccagcg ccgcgccgct gtcattaatc tgcacaccgg
     5041 cacggcagtt ccggctgtcg ccggtattgt tcgggttgct gatacgcttc ggactgacca
     5101 tccggaactg tgtccggaac agtcgcgacg ggctggtatc ccaggtggcc tgaacgaaca
     5161 gttcaccgtt aaaggcgtgc atggccacac cttcccgaat catcatggta aacgtgcgtt
     5221 ttcgctcaac gtcaatgcag cagcagtcat cctcggcaaa ctctttccat gccgcttcaa
     5281 cctcgcggga aaaggcacgg gcttcttcct ccccgatgcc cagat
//
LOCUS       DAPHKZ010000210         5163 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.211, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000210 DAPHKZ010000000
VERSION     DAPHKZ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5163
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.211"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(65..973)
                     /gene="galU"
                     /locus_tag="RH288_004448"
     CDS             complement(65..973)
                     /gene="galU"
                     /locus_tag="RH288_004448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDV4033421.1"
                     /translation="MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNTLGTEFKAWLEEEMGIKK"
     gene            complement(1175..2188)
                     /gene="rssB"
                     /locus_tag="RH288_004449"
     CDS             complement(1175..2188)
                     /gene="rssB"
                     /locus_tag="RH288_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HDV4033422.1"
                     /translation="MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDAL
                     ELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
                     QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALL
                     LRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLI
                     LVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLML
                     SAE"
     gene            complement(2280..3185)
                     /gene="rssA"
                     /locus_tag="RH288_004450"
     CDS             complement(2280..3185)
                     /gene="rssA"
                     /locus_tag="RH288_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HDV4033423.1"
                     /translation="MRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGS
                     LVGAAYACDRLSALEDWVTSFSYWDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEI
                     ENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVAHNGYWLVDGAVVN
                     PIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLG
                     SITTRRAVTAPTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAH
                     AAIAAGQLAVERKMDELLPLVRTNI"
     gene            3298..3756
                     /locus_tag="RH288_004451"
     CDS             3298..3756
                     /locus_tag="RH288_004451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HDV4033424.1"
                     /translation="MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQ
                     DADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTE
                     GGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ"
     gene            3806..4648
                     /gene="purU"
                     /locus_tag="RH288_004452"
     CDS             3806..4648
                     /gene="purU"
                     /locus_tag="RH288_004452"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HDV4033425.1"
                     /translation="MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLTRNEHDQKMADAIDAYQ
                     PDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNR
                     TIIL"
     gene            4808..4892
                     /locus_tag="RH288_004453"
     tRNA            4808..4892
                     /locus_tag="RH288_004453"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4842..4844,aa:Tyr,seq:gta)
     gene            4936..5060
                     /locus_tag="RH288_004454"
     ncRNA           4936..5060
                     /ncRNA_class="other"
                     /locus_tag="RH288_004454"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
BASE COUNT         1351 a         1310 c         1168 g         1334 t
ORIGIN      
        1 ataagctata aaaaaacggc gtcgattgct caacgccgtt tcgtggataa caccgatacg
       61 gatgttactt cttaatgccc atctcttctt caagccaggc tttaaattcc gtgccaaggg
      121 tgttatgacg aataccgtat tcaacgaagg cctgcatgta acctaattta ttaccgcagt
      181 catggctctt ccctttcata tgataggctt ccaccgtttc tttttcgatc agcatatcaa
      241 ttgcgtcggt gagctgaatt tcatcaccag ctcccggagg ggtttttgcc agcaacggcc
      301 aaatatccgc gctaagtacg taacgaccca caatagcgag attagacggc gcaacatccg
      361 ctttcggttt ttctaccaca ccaaccatcg gtacgctttc acccggcgct aattcaacgc
      421 ctttgcaatc cacaacgcca tatgcggtca catcagcaac cggttcaacc atgatctggc
      481 tatgacccgt ttcatcaaag cggcggatca tctctgccag gttatcctgt gacaaatcgg
      541 attcatattc atccagaata acatcaggca aaataacagc taccggttca tcacccacta
      601 ccgggtgagc acacaatacc gcgtgtccca ggcctttcgc cagaccctga cgaacttgca
      661 taatagtcac gtgcggtgga caaatagact gcacttcatc aagcagttga cgttttacac
      721 gtttttccag cattgcttcc agttcaaaac tggtatcaaa gtggttttca atagagtttt
      781 tagatgagtg tgtaaccagc acaatttcag taatgccagc cgcaatacat tcattcacga
      841 cgtattgaat taatggctta tcgacaagtg gcagcatctc tttcgggatg gctttcgtcg
      901 ccggcaacat cctggttcct aatcccgcaa cggggataac ggcttttttg actttcgtat
      961 taatggcagc catttaaatt ctcctggact gttcgtgttt tgaacgtgtt catatttctg
     1021 tatcgcatcc cagtatatca gcaccccgaa ggggctaagt tctgaaaagg aggcgagtta
     1081 gcataattaa gacaattact tatacgaatg gcgacgatag taccaccagc cgacattagc
     1141 aggtaatgca aatttagccc gcgttatcgt ttgctcattc tgcagacaac atcaagcgca
     1201 gtcgaccacc ggttccccat atttggcatt gccaggcatc gcatcgctgg ctcaattgat
     1261 tcaaataagc gttacctaaa gtgcctaacg gaacaccatt actgatttgc acctggtgtt
     1321 cgccggtatt taacgtcgca ttcagacccg cagaaaccag aatgagattt ttcagttcgc
     1381 gatgataata gccaactaat agcggaaact gccccggcag attggcctga cgaagtaaat
     1441 ggtttacctg cttcaataac gcgcccaact ctggcaaccg ttgattttgg tgtgcaagct
     1501 gttcctgtaa taatccgtta aacaatgcgc gtaataacaa ggcagcaagt acgccattat
     1561 gtccagctcg ggtgacatca aggcaataaa atgccagatc gttttccgaa agtgcggcaa
     1621 tatcaagcac caggccgggt ttgtccgcgg caaccaattg acgataatta acccggcaat
     1681 gggaaatcac ctgctgaacc ggcggttgta gttcctgtaa taatttcgcc gctgcggcag
     1741 ggttatcaac cattgcatcc cagtcgcgaa aaagcctttc ctcttcctca acgcgcgaat
     1801 taaacatgct gggatagaga caggcaaaaa ccatctcgcg caagcgattc agatctttaa
     1861 ctggtttcag caaaacatct tcaacgccca gacgtaacgc tttggcaata tctgccatat
     1921 tttcagtggc agatatcacc agaactgggg tctggtcgcc tctgttacgt atatgctcca
     1981 gcagtttaag cccgttcatt cgtggcatcg cgatatcaca tatcatcagg tctggagtga
     2041 aacctcccag caactcaagg gcatccaccc catcagccgc cagtaccgtt gtcgctccca
     2101 atgaggaaaa ccatgaatcc agaagcgagc gaaatacctg ctcatcttca acaatgagaa
     2161 tctgttttcc gaccaatggc tgcgtcatgt tctctcccct gactggcttt actcaatagt
     2221 ggcatgctat tgccacctgc gcctgtcaga attaacttaa gtgtagataa aaattctggt
     2281 caaatgttgg tgcgtaccaa cggcaaaagt tcgtccattt tcctttccac tgccagctgt
     2341 ccggccgcaa tggcagcgtg cgcgcgatgg aaatcaagcg tagatatttg cgggcaaaca
     2401 ggttgaatca gaatatcggg cggatcacct gccatgcggt tccttttaag gcggttctcc
     2461 agcacctgga tagaagtggt cataatctct gttgccgttg gcgctgtcac cgcccgacgt
     2521 gtcgttatgc tgcctaacct ttctttcaga cgcgcatgcc acggcagaga atcaccattc
     2581 tcgctatttt cttcactgac attaaaggag agcaaatctt gttgcatcaa atgagcatcg
     2641 tgctgcaggt caaccgctat cacaatatca gcccccaatg cacgcgtgag ggaaatagga
     2701 attgggttaa cgactgctcc atcaaccagc cagtagccgt tatgtgcaac aggtgccatg
     2761 agtcctggaa tactgcatga tgcgcgaata gcaagatgga gatcgccttc agtaaaccat
     2821 aattcacgtc ccgtacttaa attggtggca acagccgcaa agcgacggga acaattttcg
     2881 atctctgttt ccggcattat ttcgcggtat tgattgaaga cacgctcgcc gcgcagtaac
     2941 ccaccgcgct gccaggagag atccatcagg cgtaaaacat cccaataact gaaagaggtc
     3001 acccaatctt ccagcgcaga taatcgatcg catgcatagg cagcgcccac cagcgaacca
     3061 attgaacatc ctgcaacgat atcaatttca atacccactt tttttagcgc attaataacg
     3121 ccaatatgcg accaacctct cgccgcgcca gatcccagcg ccagccctat ttttatcttt
     3181 ctcattattc ccgcaagatt cccctggaat gcaatcgtag ccacatcgct actgctcggt
     3241 taacatagtg ctactcaggc ggttaatacg ccgttattgt ttccagggag attatttgtg
     3301 tctcagcttt gtccctgtgg tagtgctgtc gagtatagcc tatgttgcca cccttatgtg
     3361 tctggtgaaa aggttgcacc tgatccagaa catctcatgc gttcgcgtta ctgcgctttt
     3421 gtgatgcaag acgcagatta tttaataaag acctggcatc cctcttgtgg agcagcggcg
     3481 ttacgtgccg aattgatggc cggatttgcg catactgaat ggttgggatt gaccgtattt
     3541 gaacattgtt ggcaggacgc cgacaatatc ggatttgtca gttttgttgc tcgatttacc
     3601 gaaggtggta aaacaggtgc aataattgaa cgttcgcgat ttttgaaaga aaacggtcaa
     3661 tggtactata ttgacggtac acgtccgcag tttggtcgca acgatccctg cccttgtggt
     3721 tcaggtaaaa aatttaaaaa gtgctgcggc caataatggt tgacggtacg gtttagcaaa
     3781 cactctcaac aaggtttttc cagcaatgca ttcactccaa cgtaaagttc tgcgtactat
     3841 ttgtccggac caaaaaggtc tgatcgcacg tattaccaat atttgctaca agcacgagtt
     3901 aaatatcgta cagaacaatg aatttgttga tcaccgtacc gggcgctttt ttatgcgcac
     3961 ggaactggaa gggattttta atgattccac cctgctggcg gatctcgata gcgcattgcc
     4021 agaaggctcc gtgcgtgagc tgaatcctgc cggtcgtcgc cggatagtga ttctggtcac
     4081 taaagaagcg cattgccttg gcgatttgtt gatgaaagcc aattacggcg gcctggatgt
     4141 cgaaatcgcg gcagttattg gtaaccacga tactttacgt tctctggttg agcgttttga
     4201 tattccgttt gagctggtaa gccatgaagg gttaacccgc aacgagcacg atcaaaagat
     4261 ggcggatgcc attgatgctt atcaacctga ctacgtggtg ctggcgaagt atatgcgggt
     4321 attaacgccg gaatttgtgg cacgcttccc gaataagatc atcaatattc accattcatt
     4381 cctgccagcg tttattggcg cacgtcctta tcaccaggcc tatgaacgtg gtgtgaagat
     4441 tattggcgca accgctcact atgtgaatga caatctggac gaaggcccaa tcatcatgca
     4501 ggacgttatt catgtcgatc atacctacac agctgaagat atgatgcgcg caggtcgtga
     4561 cgtcgagaaa aacgtcttaa gtcgtgcact atacaaagta ctggcacagc gcgtctttgt
     4621 ttacggtaat cgaacgatta ttctttaatc gccagcaaaa ataactggtt acctttaatc
     4681 cgttacggat gaaaattacg caaccagttc atttttctca acgtaacact ttacagcggc
     4741 gcgtcatttg atatgatgcg ccccgcttcc cgataaggga gcaggccagt aaaaagcatt
     4801 accccgtggt ggggttcccg agcggccaaa gggagcagac tgtaaatctg ccgtcatcga
     4861 cttcgaaggt tcgaatcctt cccccaccac cataattcac cacagcgatg tggtaacttc
     4921 ggtgagattg tgaaagtttg cactcatcgg ggaagggtga gaaccttcga ctaaggttcg
     4981 attcgagcga aagcgagaga acgttgccac aggcaacgac ccgaagggcg aagcgacgaa
     5041 taatccttcc cccaccacca tctcaagcat tacctcaaaa tttgaattac ccctggtggg
     5101 gttcccgagc ggccaaaggg agcagactgt aaatctgccg tcatcgactt cgaaggttcg
     5161 aat
//
LOCUS       DAPHKZ010000211         5129 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.212, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000211 DAPHKZ010000000
VERSION     DAPHKZ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5129
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.212"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            37..990
                     /locus_tag="RH288_004455"
     CDS             37..990
                     /locus_tag="RH288_004455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415162.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HDV4033426.1"
                     /translation="MDSNNQIEPCLSRKSSEGKPQIFTTLRNIDLNLLTIFEAVYVHK
                     GIVNAAKVLNLTPSAISQSIQKLRVIFPDPLFIRKGQGVTPTAFAMHLHEYISQGLES
                     ILGALDIEGSYDKQRTITIATTPSVGALVHPVIYRAIKTHYPQLLLRNPPISDAENQL
                     SQFQTDLIIDNMFCTNRTVQHHVLFTDNMVLICREGNPLLSLEDDRETIDNAAHVLLL
                     PEEQNFSGLRQRVQEMFPDRQINFTSYNILTIAALVANSDMLAIIPSRFYNLFSRCWP
                     LEKLPFPSLNEEQIDFSIHYNKFSLRDPILHGVIDVIRNAF"
     gene            1199..2164
                     /gene="lipA"
                     /locus_tag="RH288_004456"
     CDS             1199..2164
                     /gene="lipA"
                     /locus_tag="RH288_004456"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HDV4033427.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKS
                     PQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(2265..2468)
                     /gene="tatE"
                     /locus_tag="RH288_004457"
     CDS             complement(2265..2468)
                     /gene="tatE"
                     /locus_tag="RH288_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HDV4033428.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMN
                     DDDAAAKKGADVDLQAEKLSHKE"
     gene            complement(2597..3385)
                     /locus_tag="RH288_004458"
     CDS             complement(2597..3385)
                     /locus_tag="RH288_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
                     /protein_id="HDV4033429.1"
                     /translation="MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLA
                     RDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG
                     NIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
                     LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPF
                     GVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL"
     gene            3478..3861
                     /gene="crcB"
                     /locus_tag="RH288_004459"
     CDS             3478..3861
                     /gene="crcB"
                     /locus_tag="RH288_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HDV4033430.1"
                     /translation="MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLTANLIG
                     AFIIGIGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VFVNLLGSFAMTALAFWLFSASTAH"
     gene            complement(3915..4124)
                     /gene="cspE"
                     /locus_tag="RH288_004460"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(3915..4124)
                     /gene="cspE"
                     /locus_tag="RH288_004460"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HDV4033431.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVIAL"
     gene            complement(4299..4859)
                     /gene="pagP"
                     /locus_tag="RH288_004461"
     CDS             complement(4299..4859)
                     /gene="pagP"
                     /locus_tag="RH288_004461"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HDV4033432.1"
                     /translation="MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRENIAQTWQQ
                     PEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKGNWHGLYAMAFKDS
                     WNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
                     VTFQMTYIPGTYNNGNVYFAWMRFQF"
BASE COUNT         1399 a         1270 c         1127 g         1333 t
ORIGIN      
        1 atattatttt tccatgaata aaattggagt aagtgcgtgg atagtaataa tcaaattgaa
       61 ccctgtttaa gcagaaagtc gtcagaaggt aaaccacaaa tatttacaac cttacgaaat
      121 attgatctta accttctgac tatttttgaa gctgtatatg tacataaagg gatcgttaat
      181 gcagcgaaag tgcttaatct gaccccctcg gcaatcagtc agtctattca gaaactgcgc
      241 gttatattcc ctgacccatt gtttattcgc aaaggccagg gtgtcactcc taccgcattt
      301 gcgatgcatc tacatgagta tatcagtcag ggccttgagt ccattcttgg cgcgctggat
      361 atcgaaggaa gctatgataa gcaacgaacg ataactattg cgaccactcc ctcggtcgga
      421 gcactggtcc atcctgtcat ctatcgggcg attaaaactc actatccgca gcttttactg
      481 cgcaacccgc ccatcagcga cgcggaaaac caactcagtc agtttcaaac cgatctcatc
      541 atcgataaca tgttttgcac caatcgtacg gtgcaacatc atgttctgtt caccgacaat
      601 atggtgttaa tttgccgcga gggaaatcca ctactctctt tagaagatga cagagagact
      661 atcgacaacg ctgcgcatgt acttctgtta ccggaagagc aaaatttcag cggtctgcgg
      721 cagagagttc aagaaatgtt tccggaccgg caaatcaatt tcaccagcta caacattttg
      781 acaatcgctg cactggttgc caacagtgac atgttagcga ttattcccag ccgtttttat
      841 aacctgttta gccgctgctg gccgctggaa aaactgcctt ttccgtcctt aaatgaggag
      901 caaatagatt tctctatcca ctacaacaaa ttcagcctgc gtgatcccat cctgcacgga
      961 gtaatagatg ttatccgtaa tgcattttga aaaagtattg ttacagccag atcacagcgc
     1021 agaacgataa aatggcacaa tccaacaaca attttacatt ttcgcgaccg ctttggctgc
     1081 tttcaggtcc gtttcaatga tatactgcca gtcgttaatt caaaaatagt tgataattac
     1141 aacaatctat tgaattgaaa cgctttcctt cgtaattcgc aactggaaca cgcacgctat
     1201 gagtaaaccc attgtgatgg aacgcggtgt taaataccgc gatgccgata agatggccct
     1261 tatcccggtt aaaaacgtgg caacagagcg cgaagccctg ctgcgcaagc cggaatggat
     1321 gaaaatcaag cttccagcgg actctacacg tatccagggc atcaaagccg caatgcgcaa
     1381 aaatggcctg cattctgtct gcgaggaagc ctcctgccct aacctggcgg aatgcttcaa
     1441 ccacggcaca gcaacgttta tgatcctcgg cgctatttgt acccgccgtt gtccgttctg
     1501 tgatgttgcc cacggtcgcc cggtagctcc tgatgccaat gaaccagtga aactggcgca
     1561 gaccattgcc gatatggcgc tgcgttatgt ggttatcacc tccgttgacc gtgatgacct
     1621 gcgcgatggc ggtgcccagc actttgcgga ttgcattact gccattcggg aaaaaagccc
     1681 gcaaatcaaa attgaaactc tggtgccgga tttccgcggt cgtatggatc gtgctctgga
     1741 tattctgact gcaacgccac cagatgtgtt caaccataac ctggaaaacg taccgcgtat
     1801 ttaccgtcag gtacggcctg gtgcagatta caactggtcg ctgaagctgc tggaacgctt
     1861 taaagaagcg catccggaaa tcccgaccaa gtctggtctg atggtgggac tgggtgaaac
     1921 caatgaagaa attattgagg taatgcgcga cctgcgccgt catggtgtga cgatgttaac
     1981 gctggggcaa tatttgcagc caagccgcca tcacctgccg gttcaacgtt acgttagccc
     2041 ggatgagttc gacgaaatga aagccgaagc gctggcgatg ggctttaccc atgctgcatg
     2101 cggtccgttt gtccgctctt cttaccacgc cgatttgcag gcgaaaggga tggaagttaa
     2161 gtaatcctgt aataattact tacatctgtc tgataaaaaa cccgcttttt gaagcgggtt
     2221 ttttgtatcg aacaagatat tgagggagcg tcctgctcgc cacgtcactc tttatgagag
     2281 agcttttcag cctgaagatc aacgtctgcg ccttttttcg ccgcagcatc gtcatcattc
     2341 atcgccttct tgaacccttt aatggccgct ccaaggtctc cgcccagcgt acgtaacttc
     2401 ttagtcccaa acagcagaac gaccagcgcc gcaactacca gcagtttggt aatactaatc
     2461 tcacccatag ataccttctt gacatataac cggcaacaga acgcgcctta aaaaccagag
     2521 aatattaacg gtcattcgac gcgcgcacac aatagcaatc tgtaacaagg tgaatcaagc
     2581 gccgagtaaa aaaacatcat aataattgcg gcggcgcaaa gcgacggttg tttaagacgg
     2641 gcagttgcgc gcgcacctga cgcacacgtt cgggcgtcac ttccgccata atgagtgcag
     2701 gcatttctga cgctgccgca atggtgacgc caaagggatc tataatccgg ctttgaccga
     2761 tatttttgtt cccgcactcc cccgccgcca ccatataaca ggtggtatcc agcgcacgag
     2821 cggcaagcaa cgttgaccag tgatgctctt tgagcggccc gcgaacccag gcggcaggaa
     2881 gtaccaggat ttcagctccc tgtaatgcct gtgccagcgc cagctctgga aagcgtaagt
     2941 cataacaggt catcagaccg accttcatcc cttccacctc cagtaacgga gcgatttcat
     3001 taccagcatc aacacggcgt gattcctgaa tggcaaatgc atcatagaga tgcagtttgg
     3061 cataacgggc gacgatgttt cctgcctgaa gtgccaccag catattccat gcgcgccccg
     3121 gcgttgaagg aacatgaatc gtcagaattg tcgtcatcat gttacgttta ctttctcgcc
     3181 gtaaacgtcc gaggaattcg ccttccagca gctgtgctga tttaaccgat agatctgcat
     3241 catgatcatc gcgcgccagc aatgcttccg gcaggacaaa cagcgatacg tcgttttccg
     3301 ccgcctgcgc catcaacgag gcacaaatct cagcgttctt ttcccacaca gatgtaacag
     3361 caaactgtcc tgcggcaacc agcattgcca cctcctgtca gagtcgtaaa attcgccaac
     3421 gacgattatt cggcgttaca cttatcactc atacaaatca aatagcagga ttttgcagtg
     3481 ttacaacttc ttttagcagt ttttattggc ggtggtacgg gaagcgtggc gagatggctg
     3541 ttaagtatgc gatttaaccc actgcatcag gcgattccgt tggggacgct gacagcaaac
     3601 ctgattgggg cattcatcat aggaatagga ttcgcatggt tcagcaggat gacgaacatt
     3661 gatccagtgt ggaaagtatt aatcaccacc ggattttgtg gcggtctaac aaccttctca
     3721 acattttcgg cagaagtggt gtttttgtta caagagggcc gctttggctg ggcattactg
     3781 aacgttttcg tcaaccttct ggggtctttt gccatgaccg cactggcatt ctggctgttt
     3841 tcggcctcaa ccgcacacta aagaccaaaa aaaacccgct gattaagcgg gttttgaatt
     3901 cttgctgacg tatcttacag agcgattacg tttgcagcag aagggccttt ggcaccgtta
     3961 gtgatttcga actctacgcg ctgaccttca gcaagagttt taaaaccatt agtctggatt
     4021 gcagagaagt gtacgaacac gtctttgctg ccgtcttccg gagtaatgaa accgaatcct
     4081 ttggactcat taaaccactt aacgttacct ttaatcttag acatcaaaat tacctttaca
     4141 tgaaaaatag acacaaatgc tgtgtcggtt accagtacac caattgtggt acgctttgtc
     4201 cagtgtaact ttactaaaaa gtgataaaag tcgcgttatt tttgatgtta cttattttag
     4261 ctattgattt taaagaagtt actaaaactt catttgtctc aaaactgaaa gcgcatccag
     4321 gcaaagtaca cattgccatt gttgtaggta cccggaatgt aggtcatctg aaaagtcact
     4381 gggccataac ccacggaggc caatggcagt agaaccggga gagggatgta attccagtta
     4441 tcgcgtgccg ttacgccagc ggtgaatccc agacctaaat gaaaattttc atccgccagc
     4501 ggtcgccagg tactttccca tccgtatccg gcaatcggtt cccatttgtt ccacgagtcc
     4561 ttaaatgcca tggcatacag gccatgccag tttccttttt catcccaacg cgacaggcca
     4621 aaaccgccac cccacggtcg ctcgttatag cgatcggttt tttctttgtc gtaagcgaaa
     4681 cgtgcatgcc aggtgatggc aggaatatat aaatcataat gttcaggctg ttgccaggtt
     4741 tgtgcaatat tttctctaaa cgttgtcatc cactcatctg cgttagcaaa aactttacca
     4801 acgctgatta actgaataaa aacaaaggaa aagatagcga catatttact cacgttcatt
     4861 tgtgaccata aaacatttat caaaaatcta ctactagcat agcaaagcta caattaacat
     4921 aaccttaata gacccaacat aaagaataat ctgaatagct gctctattta tttccgcttg
     4981 ttcaagttaa atatttccgc gcatcgatta aagatgatgc gtcgttttct gcgatgggaa
     5041 tagtcaaaaa agaaaaacca agtctttttt gatgacaaaa tgcaatcaag gaaaaattat
     5101 tttatttttt aacgagatac aacaatcat
//
LOCUS       DAPHKZ010000212         4987 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.213, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000212 DAPHKZ010000000
VERSION     DAPHKZ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4987
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.213"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1255
                     /gene="tssI"
                     /locus_tag="RH288_004462"
     CDS             <1..1255
                     /gene="tssI"
                     /locus_tag="RH288_004462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDV4033433.1"
                     /translation="SAQIRPSSVVTKDYTFKRPGWAGRFEQEGQHQDYQRTQYEVYDY
                     PGRFKSAHGQNFARWQMDGWRNNAETARGMSRSPEIWPGRRIVLTGHPQANLNREWQV
                     VASELHGEQPQAVPGRQGAGTALENHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPA
                     GEEIFCDEHGRVRVKFNWDRYNPADQDSSCWIRVAQAWAGTGFGHLAIPRVGQEVIVD
                     FLNGDPDQPIIMGRTYHQENRTPGSLPGTKTQMTIRSKTYMGSGFNELKFDDATVREQ
                     VYIHAQKNMDTEVLNDRTTTVKHDHRETVKNDQTVTIQEGNRLLTVEKGHKITGVLKG
                     SLSEDVFQDRGTIAGSVHVDAVNNGGEGDGIQAYTAIKEILLAVEESKIALTPDGIQL
                     QVGESTVIRLSKDGITIVGGSVFIN"
     gene            1283..1744
                     /locus_tag="RH288_004463"
     CDS             1283..1744
                     /locus_tag="RH288_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcrB-related protein"
                     /protein_id="HDV4033434.1"
                     /translation="MQFTFNEGHIQLPSQWQDQSMQVLVSTDNSGINLVITREAVPQG
                     TLTPELYQETLALYQGKLDGYTEHACREITLAEAPAWLLDYSWNGPEDEGNQGRISQI
                     AVFQRRGDTLLTFTFSTSLSLKNSQKTMLLEVIKSFTPLPPENDIQKDQPR"
     gene            1764..>4987
                     /locus_tag="RH288_004464"
     CDS             1764..>4987
                     /locus_tag="RH288_004464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HDV4033435.1"
                     /translation="MSEGPGGPQGATAGGTLAMRMLSQQAMVASQMKRAANDKAIAQM
                     LAAKKSGPPAARLGDEIQHKSFLGALAGAVLGAIVTIAEGCLIMAACATGPYALVLVP
                     ALMYASYKASDYVEEKQNQLESWINSFCDTDGAINTGSENVNINGKPAARAAVTLPPP
                     PPPGAIPEIPQGEPSWGDIATDLLESAAEKAVPLAKAWGNAVITLTESNAGFMDRVSA
                     GASLLFPAGPVLMEFATMVGGRGEIKKDVDFPEAGEDTALCDKENKPPRIAQGSSNVF
                     INNQPAARKGDKLECSAAIVEGSPDVFIGGEQVTYLDIQPEFPPWQRMILGGITIASY
                     LLPPAGLLGKLGNLAKLGKLGNLLGKSGKLLGAKLGALLGKTGKSLKSIANKVIRWVT
                     DPVDPVTGAYCDERTDFTLGQTLPLSFTRFHSSVLPLHGLTGVGWSDSWSEYAWVREQ
                     GNRVDIISLGATLNFAFDGESDTAVNPYHAQYILRRRDDYLELFDRDALSSRFFYDAF
                     PGMRLRHPVTDDTSDDRLAHSPADRMYMLGGMSDTASNRITFERDSQYRITGVSHTDG
                     IRLKLTYHASGYLKAIHRTDNGIQTLATYEQDARGRLTEADARLDYHLFYEYDAADRI
                     IRWSDNDQTWSRFTYDAQGRCVTVTGAEGYYNATLDYGDGCTTVTDGKGIHCYYYDPD
                     GNILREAAPDGSTTTYEWDEFHHLLARHSPAGRVEKFEYNAAHGQLSRYTAADGAEWL
                     YRYDERGLLSNITDPAGQTWTQLCDERGLPVSLVSPQGEETRLAYTAQGLLSGIFRQD
                     ERRLGIEYDHHNRPETLTDVMGREHHTEYSGHDLPVKMRGPGGQSVRLQWQQHHKLSG
                     LERAETGAEGFRYDRHGNLLAYTDGNGVVWTMEYGPFDLPVARTDGEGHRWQYRYDKD
                     TLQLTEVINPQGESYLYVLDNCGRVTEEHDWGGVVWRYRYDADGLCTARVNGLEETIL
                     YSRDAAGRLAEIITPEGKTQYAYDKSGRLTGIFSPDGTSQRTGYDERGRVNVTTQGRR
                     AIEYHYPDEHTVIRCILPPEDERDRHPDESLLKTTYRYNAAGELT"
BASE COUNT         1206 a         1389 c         1523 g          869 t
ORIGIN      
        1 cagcgcacaa atccgccctt cttccgtggt gaccaaagac tacaccttta aacgccccgg
       61 ctgggccgga cgttttgaac aggaaggcca gcaccaggac taccagcgca cgcagtatga
      121 agtgtatgac taccccggac gtttcaagag cgcccacggg cagaactttg cccgctggca
      181 gatggacggc tggcgaaaca acgcagaaac cgcgcgggga atgagccgct cgccggagat
      241 atggccggga cggcgaattg tgctgacggg gcatccgcag gcgaacctga accgggaatg
      301 gcaggtggtg gcaagtgaac tgcacggcga acagccacag gcggtgccag gacggcaggg
      361 agcggggacg gcgctggaga accattttgc ggtgatcccg gcagacagaa catggcgacc
      421 acagccgttg ctgaaaccgc tggtcgacgg cccgcagagc gctgtcgtga caggaccggc
      481 aggcgaggaa atcttctgcg acgaacatgg tcgcgtgcgg gtgaagttca actgggaccg
      541 ttataacccg gcagaccaag acagttcgtg ctggatccgt gtggcacagg cgtgggcagg
      601 caccggtttt ggccacctgg cgataccgcg tgtgggtcag gaggtgattg tagacttcct
      661 caacggcgat ccggaccagc cgatcattat ggggcgcacc taccaccagg aaaaccgcac
      721 ccccggcagc ctgccgggaa caaagacgca gatgaccatc cgctccaaaa cgtacatggg
      781 cagcggattt aatgagctga agtttgatga tgcgacagtg agagaacagg tctacatcca
      841 cgcgcagaag aacatggata ccgaagtgct caacgaccgt accaccaccg taaaacacga
      901 tcaccgcgaa accgtaaaaa atgaccagac ggtcacgatc caggaaggta accgccttct
      961 tacggtggaa aaaggccaca agatcaccgg agtactgaaa gggtctttat ctgaggatgt
     1021 ctttcaggac agaggcacga ttgccggttc ggtgcatgtt gacgctgtaa acaatggtgg
     1081 cgaaggcgac ggtatacagg cttatacggc gattaaggaa attttgctgg ctgtggagga
     1141 aagcaaaatt gcgctgacgc cggatggcat tcagctacag gtcggggaat cgacggtaat
     1201 caggctgtcg aaggatggca tcaccatcgt gggcggttct gttttcatca actgattcac
     1261 tcagattatc agggagtatt ttatgcagtt cacttttaat gaaggccaca ttcaactgcc
     1321 gtctcaatgg caggatcagt caatgcaggt cctggtgtcc acagataaca gtggcatcaa
     1381 cctggtcatt acccgcgaag ccgttccaca gggaaccctg acaccagagc tgtaccagga
     1441 aacgctggcg ctgtaccagg gcaaacttga tgggtacacc gaacatgcct gccgggaaat
     1501 cactctggca gaggccccgg cctggctgct ggattattcc tggaacggtc cggaagatga
     1561 ggggaatcag gggcggatta gccagatagc cgtattccag cggcgtggag atacgctgct
     1621 gaccttcact ttcagcacct ccttatccct gaagaacagt caaaagacga tgctgctgga
     1681 ggtgataaag agcttcaccc cgttgccacc ggagaatgac atccaaaagg accagccgcg
     1741 ctgacataaa cgagggataa cacatgagtg aaggaccagg cgggccacag ggagcgaccg
     1801 caggcggtac gctggcaatg cgaatgctgt cacagcaggc gatggtcgcc agccagatga
     1861 aacgggcagc caacgacaaa gccattgcac agatgctggc agcaaagaag tccggcccac
     1921 ctgccgccag gctgggcgat gaaattcagc ataaaagttt tctgggggca ctggcagggg
     1981 ccgtgctggg ggcgatagtg accatcgcag aaggttgcct gattatggcc gcctgcgcca
     2041 ccggccctta tgcgctggtt ctggtgcctg cgctgatgta tgccagctat aaggcgagtg
     2101 attatgtgga ggagaaacag aaccagcttg aatcatggat aaacagcttt tgtgacacgg
     2161 acggcgccat caataccggt tctgaaaatg taaacattaa cggaaagccc gctgcaaggg
     2221 ccgccgtcac ccttccccct cctcccccac ctggagcaat acctgaaatc ccacaggggg
     2281 aaccctcatg gggtgatatt gccactgacc tgcttgaatc ggcagcggaa aaagcagtac
     2341 cactggcgaa ggcctggggg aacgctgtta tcaccctgac ggaaagcaat gccggtttta
     2401 tggatcgcgt cagcgccggc gcatcgcttc tgtttcccgc cggtccggta ttaatggagt
     2461 ttgccaccat ggtgggcggg cgtggcgaaa tcaaaaaaga tgtggatttc ccggaagccg
     2521 gtgaggacac ggcgctctgc gacaaggaga acaaaccacc gaggatagcc cagggcagta
     2581 gcaacgtctt tatcaacaat cagcctgccg cgcgcaaggg cgacaaactg gagtgcagtg
     2641 cggcgatcgt ggaaggttcg ccggacgtct ttattggggg tgagcaggtc acctatctgg
     2701 atatccagcc ggagttcccg ccatggcaga gaatgatcct gggaggaata acgatagcca
     2761 gctatcttct gccgccagca ggactgctgg gaaaactggg gaatctggcg aaactgggca
     2821 aactgggaaa cctgctgggg aaaagcggga agctgctggg cgcaaagctc ggcgcgttgc
     2881 tggggaaaac aggtaagtcg ttaaaaagta ttgccaataa agtcatcaga tgggtaacag
     2941 atcctgtcga tccggtaacc ggcgcgtact gcgacgaacg taccgacttc accctgggcc
     3001 agaccctccc cctctccttc acccgtttcc acagttcggt actgccactg catggcctga
     3061 cgggcgtggg ctggagtgac tcctggagcg aatacgcctg ggtgcgtgaa cagggaaacc
     3121 gggtggatat catcagcctg ggagccacgc tgaacttcgc cttcgacggt gaaagtgata
     3181 cggcggttaa cccgtatcac gcccagtaca ttctgcgccg ccgtgatgat tatctggagc
     3241 tgttcgacag ggatgcactg agcagccgct tcttttatga cgcctttccg ggaatgcgtc
     3301 tgcgccaccc ggtgactgac gataccagcg atgaccgcct ggcacacagc cccgcagacc
     3361 ggatgtacat gctgggcggg atgagcgaca ccgccagcaa ccgcatcacg tttgagcgcg
     3421 acagccagta ccggatcacg ggtgtcagtc acaccgacgg gatccggctt aaactgacgt
     3481 accacgccag cggctacctg aaagccattc accgcacgga taacggcata cagacgctgg
     3541 cgacctacga acaggatgcg cgggggcggc tgacagaagc ggatgcgcgg ctggactacc
     3601 acctgtttta tgagtacgac gctgcggacc ggatcatccg ctggtccgat aacgaccaga
     3661 cgtggagccg tttcacctac gatgcacagg gccggtgcgt gaccgtcacc ggggcggagg
     3721 gctattacaa cgccacgctg gactatggtg acggctgcac caccgtgacg gacggcaagg
     3781 gcattcactg ttattactat gatcctgacg gcaatattct gcgggaagca gcgccggacg
     3841 gcagcaccac cacgtatgaa tgggatgaat tccatcacct gctggcccgc cactcccctg
     3901 ccgggcgggt ggagaagttt gaatacaacg ccgcacacgg tcagttaagc cgttacacgg
     3961 cggcagacgg cgcggagtgg ttgtaccgct atgatgagcg cggcctgctc agcaacatca
     4021 ccgaccctgc cgggcagacg tggacacagc tgtgcgatga acgcggcctg ccggtaagcc
     4081 tggtgtcgcc acagggcgaa gagacccggc tggcgtacac cgctcagggg ctgttgtcgg
     4141 gaatattccg ccaggatgaa cggcgtctgg gcatagagta cgaccaccac aaccggccgg
     4201 aaacactcac cgacgtgatg ggccgtgaac accataccga atacagcggt cacgacctgc
     4261 cggtgaagat gcgcggcccc ggcggtcagt cagtgcggtt acagtggcag cagcaccata
     4321 aactgagcgg ccttgagcgg gcagaaaccg gcgcagaagg attccgctat gaccgccacg
     4381 gcaacctgct ggcgtacacg gacggtaacg gcgttgtctg gacaatggaa tacggcccgt
     4441 tcgatttgcc ggtggcgcga acggacggtg aaggccaccg ctggcagtac cgctacgata
     4501 aagacacgct gcaactgaca gaagtcatta acccgcaggg cgaatcatac ctttatgttc
     4561 tggataactg tggccgggtg acggaagagc atgactgggg cggcgtggtc tggcgttacc
     4621 gctatgacgc cgatggcctg tgtaccgcca gggttaacgg cctggaggaa actatcctct
     4681 acagccggga cgccgcaggc cgcctggcag aaatcatcac gccggaaggc aaaacgcagt
     4741 atgcgtatga caaatccggc aggctgacgg gtatcttcag cccggacggt acatcacagc
     4801 gcaccggcta tgatgaacgc gggcgggtga atgtcaccac tcagggccga cgggccattg
     4861 aataccacta ccccgatgaa cacaccgtta tccgctgtat cctgccaccg gaagatgaac
     4921 gcgacagaca ccccgatgaa tccctgctga aaaccacgta ccgctacaac gccgccggag
     4981 aactgac
//
LOCUS       DAPHKZ010000213         4936 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.214, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000213 DAPHKZ010000000
VERSION     DAPHKZ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4936
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.214"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            33..797
                     /locus_tag="RH288_004465"
     CDS             33..797
                     /locus_tag="RH288_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1120 domain-containing protein"
                     /protein_id="HDV4033436.1"
                     /translation="MFFKKNLTTAAICAALSVAAFSAMATDSTDTELTIIGEYTPGAC
                     TPVVTGGGIVDYGKHHNSALNPTGKSNKLVQLGRKNSTLNITCTAPTLIAVTSKDNRQ
                     STIVALNDTSYIEKAYDTLVDMKGTKNAFGLGSAPNGQKIGAASIGIDRSNGGIHAAD
                     DTGEIPVDLIQTDHWSAATPTWKASSNGAFCSLTSCSAIERGYSVAKTGELTPVAITA
                     VTFPLLIDAAVNDNTILGSDETIKLDGNVTISVQYL"
     gene            969..1643
                     /locus_tag="RH288_004466"
     CDS             969..1643
                     /locus_tag="RH288_004466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV4033437.1"
                     /translation="MLRHITFTVFITTSMNTLATGMVPETSVLLVDEKRGEASINIKN
                     TDDHPSLLYTTIVDLPESNKSIRLIPTQPVIRVEAGQVQQVRFLLQATVPLQSEELKR
                     VTFEGIPPKDDKSSRVTVSIRQDLPVLIHPASLPEERETWKFLEWRKNGDQIEISNPS
                     NYVVRMTLQFKTLPSGKTGAINKTYFLPHTSTTTALTNATDTKVEFYPASRYGYRGNK
                     YVTDLK"
     gene            1664..4045
                     /locus_tag="RH288_004467"
     CDS             1664..4045
                     /locus_tag="RH288_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HDV4033438.1"
                     /translation="MLKKTLLAYTIGFAFSPPANADGIEIAAVDFDRETLKSLGVDPN
                     ISHYFSRSARFLPSEYSLIVSVNGEKKGNIATRFDENGDICLDQAFLQQAGLKIPSEE
                     KNGCYDYILSYPGTTITPLPNQEALDIIVSPQAIIPIGLDLTNAATGGTAALLNYSLM
                     SSRAEFSNGSSDYSQAALEGGININDWMLRSHQFLTQTNGTFSNQNSSTYLQRTFTDL
                     KTLMRAGEVNLNNSVLEGASIYGIEIAPDNALQTSGSGVQVTGIANTSQARVEIRQQG
                     VLIHSILVPAGAFTIPDVPVRNGNSDLNVTVVETDGSSHNYIVPSTLFNQHVESFQGY
                     RFAIGRVDDDYDESPWVISASSGWNLTRWSAMNGGVIVAENYQAASIRSSLVPLPDLT
                     VSSQISTSQDTKDSLQGQKYRLDANYNLPFSLGLTTSLTRSDRHYRELSEAIDDDYTD
                     PTKSTYALGLNWSNSILGGFNISGYKTYSYDGDNDSSNLNINWNKAFKHATVSVNWQH
                     QLSASENNEDDGDLFYVNISIPFGRSNTATLYTRHDDHKTHYGTGVMGVVSDEMSYYV
                     NAERDHDERETSLNGSISSNLHYTQVSLAAGASGSDSRTYNGTMSGGIAVHDQGVTFS
                     PWTINDTFAIAKMDNNIAGVRITSQAGPVWTDFRGNAVIPSIQPWRTSGVEIDTASLP
                     KNVDIGNGTKMIKQGRGAVGKVGFSAITQRRALLNITLSDGKKLPRGVAIEDSEGNYL
                     TTSVDDGVVFLNNIKPDMVLDIKDEQQSCRIHLTFPEDAPKDVFYETATGECQ"
     gene            4042..4587
                     /locus_tag="RH288_004468"
     CDS             4042..4587
                     /locus_tag="RH288_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033439.1"
                     /translation="MKRIITGCLLLNFAMAAQAECNISSSIQNIDYGKRSAAMRQVDR
                     GKTTQLADRTITLVMQCDQDAHIRVQLNTANISNNGFGFGPNGSLNLIASDAFSGSNN
                     LDLALASGKNDNPGSTGTASISTSPNNWLVFMQNGQEVVIDSGKSVSLTLTMAPAFKD
                     EGELTDMTDITGNLTVLVEAK"
     gene            4584..>4936
                     /locus_tag="RH288_004469"
     CDS             4584..>4936
                     /locus_tag="RH288_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1120 domain-containing protein"
                     /protein_id="HDV4033440.1"
                     /translation="MNNVKLLIAGSAFFAMSAQAADRVSIDVKVTLEAAACTPILSNG
                     GVVNFGSHSVNRLSTQHYTQIGTRNINMTITCESATGIAITARDTRMDSMTTGKDSGG
                     QSGVKYTLNGGGYIS"
BASE COUNT         1488 a         1109 c         1072 g         1267 t
ORIGIN      
        1 aaaaataaat ttgttattaa ggatatgttc atatgttttt caaaaagaac ctcacaacag
       61 ctgctatttg tgcagcactt tctgttgcag cattcagtgc catggcaaca gattcaactg
      121 atacagaatt aactatcatc ggcgagtata cccctggtgc atgtacccca gttgttacgg
      181 gcggcggcat tgttgactat gggaaacatc ataacagtgc gctgaatccg accggtaaaa
      241 gtaataaact ggttcaactg ggccgcaaaa acagcacatt aaatataacc tgcacagcac
      301 caacgctaat tgctgtaacc tccaaggata accgtcagtc gaccattgta gcgttaaacg
      361 acacatccta tattgaaaaa gcttatgata ctctcgtaga tatgaaggga acgaaaaacg
      421 cctttggttt aggttctgcg cctaatggac aaaaaattgg cgctgcatcc attggtattg
      481 acaggtctaa tggtgggatt cacgcggcgg acgatacagg tgaaattcct gtcgacctga
      541 ttcaaactga ccactggtca gcagcgaccc ccacatggaa agcctcatct aatggcgcat
      601 tctgctcgct gacaagttgc tcagcaatcg agcgcggtta ttctgttgca aaaacagggg
      661 aactgacacc tgttgccatt acagcggtca ccttcccgtt actgattgat gctgcggtaa
      721 atgacaatac tattcttggt tctgatgaaa cgatcaaact ggatggtaac gtcactatca
      781 gcgttcagta tttataagaa cttgtaatac agtttttatt tttacgcatt aaccagttag
      841 ctataactcg gacagattat gccctatgac atggtctgtc ttaatcaatc tcatcgcaaa
      901 cagtgcataa catatattaa caatatgttt ctgcgttatt tatcattatt acaggagttt
      961 taatttaaat gctcagacac attacattca ctgtatttat aacaacatca atgaatacct
     1021 tagccacagg gatggttcct gaaacatcag tattgctggt tgatgaaaag cgtggtgaag
     1081 ctagtattaa tattaagaat acagatgatc atccttcatt gctttacacc accattgttg
     1141 atttgcctga aagcaataaa tcaattcgtt taatcccgac tcagcccgtt attcgtgttg
     1201 aagccggtca agtacaacag gttcgatttt tacttcaggc gactgttcct ctgcaatcag
     1261 aagagctgaa acgcgtaacg ttcgaaggta ttccaccaaa agatgacaag agcagcagag
     1321 ttactgtttc aattcgtcag gatctacctg tactgatcca cccggcttcc ctgccggaag
     1381 agcgagagac ctggaaattc ctggaatggc gtaaaaatgg cgaccaaatt gagattagca
     1441 accccagtaa ttatgtcgtt cgtatgacct tacaatttaa aacgctccct tcaggaaaaa
     1501 cgggggctat aaataagacc tattttctac cacacaccag tacaactact gcattaacaa
     1561 acgctacgga tacaaaagtc gagttttacc cagccagccg atatggttat cgcggtaata
     1621 aatatgtcac tgacttaaaa taactttgcc tggagcgaca aggatgttaa aaaaaacgtt
     1681 actggcctac accattggtt ttgccttttc tcccccagcc aatgcagatg gtatagagat
     1741 tgccgctgtt gattttgatc gggaaacatt aaaatcacta ggtgtagatc ctaatatatc
     1801 gcattatttt tcccgttcag cccgtttttt gccaagtgaa tattcactga tagtatcagt
     1861 aaatggcgaa aaaaaaggca acattgctac gcgctttgat gaaaatggcg acatttgtct
     1921 tgatcaggca tttctgcaac aagccggttt aaaaattcct tctgaagaaa aaaatggctg
     1981 ttacgactat atattgtcct acccgggtac cacaatcaca ccattaccta accaggaagc
     2041 gttagatatt atcgtttcac cacaggcgat cattcccata gggttggatc tcacaaacgc
     2101 agcaactggt ggaacagctg cgctgctaaa ctactctctg atgagcagcc gtgcagaatt
     2161 ttctaatggg agttcggact actcccaggc tgcacttgaa ggcgggatta atattaatga
     2221 ctggatgtta cgcagccatc agttccttac acaaacaaat ggcacattca gtaaccagaa
     2281 ctcgtcaacc taccttcaac gtacctttac agatcttaaa acactcatgc gagcaggtga
     2341 agttaacctc aataatagcg tgttggaagg agccagtatt tacggtatcg aaatcgcacc
     2401 ggacaacgca ttgcaaacca gcggcagtgg tgtgcaagtt actggtatag ccaacacctc
     2461 tcaggctcgt gtcgagattc gtcaacaagg agttttaatt cattccattc tggttcctgc
     2521 gggcgcattc actatccctg atgtacctgt tcgcaatggt aatagtgatc ttaatgtcac
     2581 cgttgtcgaa acagacggta gttcgcacaa ctatattgtt ccctccaccc tgtttaatca
     2641 gcatgtagaa agcttccagg gttatcgctt cgcgataggg cgggtagacg atgactatga
     2701 cgaatcacct tgggtaatta gtgcatcgag cggatggaat ctgacacgct ggagtgcaat
     2761 gaacggcggc gttatcgtag cagaaaatta tcaggcggca tcaatccggt cgagtctggt
     2821 tcccctgccc gatttaacag tgagcagcca aattagtaca tcgcaggata cgaaagactc
     2881 actgcaagga cagaaatatc gtcttgacgc gaactacaat ctcccatttt cacttgggct
     2941 aacaaccagc ctcactcgat ctgatcgcca ttatcgcgaa ctgtctgaag cgattgatga
     3001 tgattatacc gatccgacta aaagcactta tgcgcttggt ttaaactggt ctaactccat
     3061 tctgggtggt ttcaacatca gtggctataa aacatatagt tacgacggtg acaatgactc
     3121 aagcaacctt aatattaact ggaacaaagc gttcaaacac gccacggttt ccgtcaactg
     3181 gcagcatcaa cttagtgctt cagaaaataa tgaagacgat ggtgatctgt tctacgtcaa
     3241 catcagtatt ccatttggca gatcaaacac cgccacactg tatactcgcc atgacgatca
     3301 taaaacccac tatggtactg gtgtcatggg agtcgtctca gatgagatgt cctactatgt
     3361 gaatgctgaa cgagatcacg acgaacgtga aacgagcttg aacggcagta tcagttccaa
     3421 tctccattac acccaagtca gccttgccgc aggagcaagc ggcagtgata gccgtactta
     3481 caacggtacg atgtcaggtg gtattgccgt acatgatcag ggagtgacct tttcaccgtg
     3541 gactatcaat gacactttcg ccatcgcaaa aatggataac aatattgcag gtgtcagaat
     3601 tacatctcag gcaggcccag tatggacaga ttttcggggt aatgccgtca ttccatcaat
     3661 ccagccgtgg cgaacatcag gagttgagat cgataccgcc agcttgccaa aaaatgtcga
     3721 tatcggtaac ggcacaaaaa tgatcaaaca aggccgtggt gcagtaggga aagtcggatt
     3781 cagtgcgata acacaacgcc gtgcattact caatatcaca ctttccgacg gcaaaaaact
     3841 gcccagaggc gttgcgattg aagatagtga aggcaactat ctgacaacat cagtggatga
     3901 cggtgttgta ttcctcaata acatcaaacc ggacatggtg ctagatataa aagatgagca
     3961 gcaatcatgc cgtattcacc ttacattccc agaagatgca ccaaaagatg tgttctatga
     4021 gacagcaaca ggagagtgcc aatgaaacgg ataataacag gatgcctgct gctgaacttc
     4081 gccatggccg ctcaggcaga gtgtaatatc tccagtagca tacaaaatat cgactatggc
     4141 aaacgaagtg ctgccatgcg ccaagttgac cggggtaaaa caacacaatt agcagacaga
     4201 acaatcacgc tggtaatgca atgcgatcag gacgctcata ttcgtgttca gttgaatacc
     4261 gctaatattt ccaacaacgg atttggattt ggcccgaatg gttcattaaa tctgatcgcc
     4321 agcgatgcat tttcaggtag taacaatctc gacctggcgt tagccagtgg caaaaatgac
     4381 aatccgggca gcacaggaac agcatcaatt agtacttccc ccaataattg gctggtgttt
     4441 atgcaaaatg gtcaagaagt ggtaattgat agcggtaaaa gcgttagcct cacactgaca
     4501 atggctccag cttttaagga tgaaggggaa ctaaccgaca tgacagatat tacaggcaat
     4561 ctgacggtcc tggtggaggc aaaatgaaca atgtaaaatt actgattgcc ggaagtgcct
     4621 tttttgccat gtcagcgcaa gccgctgata gagtatcaat tgacgttaag gtgactctgg
     4681 aagctgcagc ttgtactcca atactaagca acggcggagt tgttaacttc ggtagtcatt
     4741 cagtcaatag actttcaacg cagcactaca cacagattgg aacacgtaat attaatatga
     4801 ctataacttg cgaatccgct accggcattg cgattaccgc tcgtgataca cgaatggata
     4861 gtatgaccac cggaaaagat agtgggggtc agagtggtgt aaaatatacc ttaaatggcg
     4921 gaggttatat tagcca
//
LOCUS       DAPHKZ010000214         4909 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.215, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000214 DAPHKZ010000000
VERSION     DAPHKZ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4909
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.215"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(61..939)
                     /gene="glxR"
                     /locus_tag="RH288_004470"
     CDS             complement(61..939)
                     /gene="glxR"
                     /locus_tag="RH288_004470"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDV4033441.1"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     SVETARQVTEASDIIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
     gene            complement(1039..1815)
                     /gene="hyi"
                     /locus_tag="RH288_004471"
     CDS             complement(1039..1815)
                     /gene="hyi"
                     /locus_tag="RH288_004471"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HDV4033442.1"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKHVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPAGFSSEQIHATLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYDYLFKVIENSDYNGWVGCEYKPQTTTEAGLRWMDPYR"
     gene            complement(1828..3609)
                     /gene="gcl"
                     /locus_tag="RH288_004472"
     CDS             complement(1828..3609)
                     /gene="gcl"
                     /locus_tag="RH288_004472"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HDV4033443.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINAD
                     AAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIADNAVDAPTETCFMHYE"
     gene            complement(3699..4514)
                     /gene="allR"
                     /locus_tag="RH288_004473"
     CDS             complement(3699..4514)
                     /gene="allR"
                     /locus_tag="RH288_004473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HDV4033444.1"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHP"
     gene            complement(4592..>4909)
                     /locus_tag="RH288_004474"
     CDS             complement(4592..>4909)
                     /locus_tag="RH288_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HDV4033445.1"
                     /translation="INRAQLANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDK
                     PDLSTLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQEL
                     CFA"
BASE COUNT         1247 a         1356 c         1109 g         1197 t
ORIGIN      
        1 ttctttttta atattgctgg ccgattcatt ttctgatatc ggccattttt attgcgggta
       61 tcaggccagt ttatggttag ccattaattc cagcgcctgc actaacgcag agtgatccaa
      121 ctggctgcca ccgtttgccg cacaggtatt aaataactcc tggcaggtcg cagtgtttgg
      181 caggttcagc gcaagtgctt tcgcactttg cagtgccagg ttgagatctt tctggtgcag
      241 agcgattttg aagcccggat taaaggtgcg tttaatcata cgctcgccat gaacttccag
      301 aatacgtgag gaagcaaagc cgcccatcag cgcctggcgc acacgtaccg ggtccgcacc
      361 ggcttttgaa gcaaatagca gggcttcaga aaccgcttca atattgagcg ccacgataat
      421 ctgatttgcc actttgcagg tttgaccatc gccgttaccg cccacgaggg tgatattttt
      481 accgagcagt tcaaacagcg gtttaacacg ttcaaatacc gcttcatcac cgccaaccat
      541 aatcgacaac gtcccttcac gcgcaccgat ttcaccgccg gagactggcg catcgagata
      601 atcgccgccc agttcattca cctgacgagc gaaacgctta gtttcaatcg gggaaatgga
      661 gctcatatca acaatggttt tgcccttcag cgaggctttg gtacaaccat tttcaccgaa
      721 cagaacttct tcaacctgag gtgtgtccgg caccataata aaaatgatgt ccgatgcttc
      781 cgttacctgg cgagcagttt caacactgac ggcacccagt gacagtaatt catcagcaac
      841 cggtccaatg gtcgtgacat gtaattgatg accggcacgc gccagattaa tggccatcgg
      901 tgtacccata atgcctaagc caataaatcc cagtttcata attaacctct tttaaatttc
      961 gcttttcctg aattcagaca acacgatccc ctgccaactt agcggcctaa aaaagcattg
     1021 tctgaatagc gttacgtttt aacggtacgg atccatccag cgtaaaccgg cttccgtggt
     1081 ggtttggggt ttatattcac acccaaccca accgttgtag tcagaatttt cgattacctt
     1141 aaagagataa tcataattaa tttctccggt tcccggttcg ccgcgatgcg gattatcggc
     1201 aatttgcagg tgaccaattt tatcagccca ctgagtcatg gtgttggtta attcaccttc
     1261 catccgctgc atatgataaa tgtcatactg aattttcaaa ttgcagcaac caacatcatc
     1321 aatcaatttc agcgcctgcc gagttccggt gagatggaaa ccaggaatat caaaatggtt
     1381 aataggttca atcagtaata aaatatcttc tttcatcagc atattcgcgg cataacgcag
     1441 gttttctaca agcgttgcgt gaatctgttc actgctgaaa ccagccggcg ttttaccgac
     1501 cagacagtta atttttttat tacccagcgc acgggcataa cgaatcgctg ctgctacgcc
     1561 atcccgaaac tcttcttcac ggccaggaat acaggcaata ccgcgctccc ccgccgccca
     1621 gtcacccgcc ggtaaattgt gcagcgtatg ttcgagttta ttactcgcca gcacatgttt
     1681 taattcttca atgtcgtagt cataaggaaa cataaattca acgccgcgaa aaccacactg
     1741 cgcagctttc tcaaaacggg cgagaaaatc atattctcca aataacatcg ataaattagc
     1801 agagaaacgt aacattattt atctccctta ttcatagtgc atgaagcagg tttcagtcgg
     1861 tgcgtccact gcgttatcgg cgatatcttc aaattccatg acgttatcca gttcgctgcc
     1921 catcgaaata ttggtcacac gctcgagaat aacttccacg actaccggta cccgatattg
     1981 cgccattaag gctttcgcct gttcaaaggc tggcgcaata tcttccggtt tgaagacccg
     2041 aatagcttta caacctaaac cttccgctac ttttacgtgg tcaacaccgt agccattcac
     2101 ttcactggag ttgatattct cgaaagcgag ttgcacgcag tagtccatgt caaaagcgcg
     2161 ttgtgactga cgaatcagcc ccagataagc gttgttgacc agcacatgga tgtacggaat
     2221 gttgaactgc gcgccaacag ctaactcttc aatcaggaac tggaagtcaa agtcgccaga
     2281 aatcgccacc acattgcgtt tcggatcagc ggcacaaacc cctagcgcag ccggaatcgt
     2341 ccagcctaac ggaccagcct gaccacagtt gatccagtgg cggtctttaa agacatgcag
     2401 catttgtgcc gcagcgattt gtgacagacc aatggtggtg acataacaaa catcgcgacc
     2461 aaaggctttg ttcatctctt catacacgcg ctgcggtttc accggcacgt tgtcgaagtg
     2521 ggttttgcgc agcaaagtgc gtttacgctg ctggcagtcg gcgacccatt ctttacgaca
     2581 cggcagacga cccgcttttt gcatctcctg cgccacttca accagcagtg tcagcgccgc
     2641 tttagcatca gagacaatac cgagatccgg acacagcacg cgaccaattt gcgtcggctc
     2701 aatatcaata tgaacgattt tgcgcccttc ggtgtatttc tctaccgagc cggtatgacg
     2761 gttagcaaaa cggttaccga taccaaacac catgtcagac gccagcagcg ttgcgttacc
     2821 gtaacgatgc gcggtttgca gacccaccat cccggccatc agttcatgat cgtccgggat
     2881 acagccccag cccattagcg ttgggatcac cggaacgctg gtcagttcag caaactgttg
     2941 taacagtgca gctgcgtcag cattaattac cccgcccccg gcaacaatca ccggacgttc
     3001 ggcctggatt aacatttcta cagctttttc gatctgcata cggctggcag caggtttgta
     3061 gaccggcagc ggttcgtaca tgtcaggatc aaactcgatt tccgcaacct gaacgtcgaa
     3121 cggtaaatcc accagtaccg gacccggacg accagaacgc atcaggtgaa atgcctgttg
     3181 cagcacgcga ggcaccagcg ccgcttcacg aactgtaacc gccattttgc tgaccggttt
     3241 agcaattgct tcaatatcta cggcctgaaa atcttcttta tgcagacggg cgcgcggtgc
     3301 ctggccggta atgcacagaa taggaatgga atcagcagaa gcggaataga gcgcggtgat
     3361 catgtccgtg cccgcaggac cggaagtccc cagacatacg ccgatattcc ctgccgttgc
     3421 gcgggtataa ccttccgcca tgtgcgaagc accttccaca tgacgcgcca gaatgtgacg
     3481 aataccgccg tgcttacgca tcgctgagta gaacggattg attgcagctc ccggaacacc
     3541 gaaggcggta gtgatacctt ctttctccag cacatacatt gccgcgtcaa cggctctcat
     3601 ttttgccatt ttattcctac ctctatttat tggaaaattt ttccaacttt caaattttgt
     3661 caaaaaaacc cgctccgcag agcgggatgc gacagacatt atggatgtgc tttcagtccc
     3721 aacgccgtgc tgatatcgcg ggcggtgtct ctgaccagct caccctgact gacaaaacga
     3781 tcttctgtca gtcttgatga aggcccggag atggagatag cggcaacaac actaccgaca
     3841 tcatcgtaaa ttgctgaagc tatgcaattc agacctacaa catgctcttc tttatctacg
     3901 gtatagccca gttcacgcgc ttgttccagg tccttcagca aggtgggcat atccacaagc
     3961 gtagttggcg taaactgctg caaaccggtt tgcagaatga tgctcatcaa ctcctcttcc
     4021 gccagcggat aaagcagcgc tttgcccgca ccggaagcat gcagtggcag acgactgccc
     4081 agtggcgcac acatcctgac catcgattta cactctaact gaccaattaa taccgcttca
     4141 ttgccgttac ggatcgcgac attgaccgtt tcgccggaaa gtaacatcag gcggcgcata
     4201 aacggcccgg cgacggagag gacatcgcgg ttatggatgt acgccgcacc gacgttaaag
     4261 acacctaatc ctatatgcca ccagcctaat tgactgtcct gatagacaaa atccgctgcc
     4321 tgtaaaacct tcagcaagcg aaaggtcgtg gagagcggca aatccagatt gagagaaata
     4381 tcgctaaccg acgaacttcc cccacttttt tccaaatatt gcagaatcgc aattccccgc
     4441 tctaacgcct gtgcgccctt ctgtgccaca ggctccgcct gtcctggcct gccgcgccgt
     4501 ctaacttccg tcatacctac gttaactccg acctacaagt gagcataaac aatgaacaat
     4561 tagtttatct tatgcaagtc ggttgcaggc gtcacgcaaa acagagttcc tgttcaggaa
     4621 tactttcaac atcacagttg tcactgccgc cgcgatcgat ggtcagaaaa tcggtgacgc
     4681 gctgccaggc gaaaagtggg tgatgccaga cgttacgatg gtaattcact ccctgttcgc
     4741 cgttggtgat aaacgcccgc agcgttgaca ggtctggttt gtcgtcacct aacgccacga
     4801 ccaccacaaa cacctcacct ttcatcggga taaaggcctg agtacccagc ggatgacgtt
     4861 cgagttcgtg aatggtcagc ggcagattcg ccagttgcgc gcggttaat
//
LOCUS       DAPHKZ010000215         4853 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.216, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000215 DAPHKZ010000000
VERSION     DAPHKZ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4853
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.216"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..2032)
                     /gene="rhsD"
                     /locus_tag="RH288_004475"
     CDS             complement(<1..2032)
                     /gene="rhsD"
                     /locus_tag="RH288_004475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhs element protein RhsD"
                     /protein_id="HDV4033446.1"
                     /translation="MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMT
                     SGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSSYRTKTPAPVGVFGPGWKAPSDI
                     RLQLRDDGLILNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLARLWG
                     ALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLPPYRVLTGMADRFGR
                     TLTYRREAAGDLAGEITGVTDGAGREFRLVLTTQAQRAEEARTSSLSSSDSSRPLSAS
                     AFPDTLPGTEYGPDRGIRLSAVWLMHDPAYPESLPAAPLVRYTYTEAGELLAVYDRSN
                     TQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGLSYRYLYEQDRIT
                     VTDSLNRREVLHTEGGAGLKRVVKKELADGSVTRSGYDAAGRLTAQTDAAGRRTEYGL
                     NVVSGDITDITTPDGRETKFYYNDGNQLTAVVSPDGLESRREYDEPGRLVSETSRSGE
                     TVRYRYDDAHSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGYQTRYEYDRFGQMTA
                     VHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQYDAW
                     GKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGR"
     gene            complement(2099..4207)
                     /locus_tag="RH288_004476"
     CDS             complement(2099..4207)
                     /locus_tag="RH288_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDV4033447.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTIWQGDEVQRRVKGVVTWFELGENDKNQMLYSMKVHPPLWRA
                     GLRQNFRIFQNEDIKSILGTMLQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAYKSTDQSLVLCDTVRHLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFEQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAETARGMSSSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGR
                     QGAGTALENHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKF
                     NWDRYNPSNQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HHENRTPGSLPGTKTQMTIRSKTYKGSGFNELKFDDATGKEQVYIHAQKNMNTEVLNN
                     RTTDVINNHAETIGNNQMIAVTNNQIQTVGVNQIETVGSNQIIKVGSVQVETIGLVRA
                     LTVGVAYQTTVGGIMNTSVALMQSSQIGLHKSLRVGLGYDVKVGNNVTFTVGKTKKDD
                     TGQTAIYSAGEHLELCCGKARLVLTKDGQIFLNGTKIHLQGKEQVNGDSLLINWNCAA
                     SKSPPKTPDEKQDTPDMREY"
BASE COUNT          963 a         1497 c         1275 g         1118 t
ORIGIN      
        1 tccgcccgtc aaagccgccc tgctgtacca gccggtccag cgcatcgtaa ctgaagacgc
       61 tgtggctgcc gttctcgttg gtcaggctga tgacacgtcc ggcagcatcg tactccatac
      121 tgcgcgtcag cccgccctgc gtggtgctga ccgcctttcc ccacgcatcg tactgtgtct
      181 cgctccggtt gccgtccggg gtgataacgg cagtcaggtc gcctgcggcg ttgtattcat
      241 accgcgtttc acggccctgt gcgtctttca ccgaggttaa ccggccacgg ttgtcatagc
      301 ggcggtaaag gctgatgcct tcctcgcggt ggaccgccgt catctggccg aagcggtcgt
      361 attcataacg ggtctggtag cccgagcagt cggtgaacgc cagcaactgc ccgtagcggc
      421 tccaggtcat ctgccgggtg ctgcccgtcg catccgttgt cgtcgccggt aactcactgt
      481 gcgcgtcatc gtagcggtag cgtactgtct ccccgctgcg cgatgtctcc gataccagcc
      541 tgcccggttc atcatattcc cggcggctct ccagcccgtc cggggacacc accgccgtca
      601 gctggttccc gtcgttatag taaaatttcg tctcccgccc gtccggtgtg gtgatgtccg
      661 tgatatcgcc ggacaccaca ttcagaccgt actctgtcct ccgtcccgcc gcgtccgtct
      721 gcgccgtgag ccttcctgcc gcgtcatacc cgctgcgcgt gacgctgccg tccgccagtt
      781 cttttttcac cacccgtttc agcccggccc cgccttctgt atgcagcacc tcacgccggt
      841 tcaggctgtc ggtgacggtg atgcggtcct gctcataaag atagcggtag cttaaccctg
      901 ccgggttcag ttgctccacc acccgccccg tatcgtcgta gcggtagcgc atctccggcc
      961 ttcccgcgta acggtgcgcc accatccggc ccgggtgctg cgcgtcatac gtgaaagcgc
     1021 gcacctgcgt attgctgcgg tcatataccg ccagcagttc accggcttcc gtatacgtgt
     1081 accgcaccag tggcgcagcg ggcaggctct ccgggtatgc cgggtcgtgc atcagccaca
     1141 ccgccgaaag gcggataccc ctgtcggggc cgtattcggt accgggcagt gtgtcgggga
     1201 acgctgaggc tgagagaggg cgggaactgt cagaagaaga tagcgaagag gtgcgggcct
     1261 cttccgcacg ctgcgcctgc gtggtcagca ccagacggaa ctcccgcccg gcaccgtccg
     1321 tcacgccggt gatttccccg gccaggtcac cggcggcctc acgccggtac gtcagcgtcc
     1381 gcccgaagcg gtccgccatc ccggtaagca cccggtacgg cggcagcggc gctggcagta
     1441 cgtcctcagc acccggcacc cgctcagacc accccagtat ccaccacggc ccctgtgcgc
     1501 tgttggtcgc caggtaaaga tgcgggctta accggatatc cggcggcagc gccccccaca
     1561 gccgcgccag cgtatggccg tccggctgtg ctgccttacc accgcgcacc agccacattg
     1621 actcactgcg gctgtacacc gcctcccccg gcagcagcgg ctcaaagtga atgctccgcc
     1681 cgccgttgtc gttgagtatc agtccgtcat cacgtagctg taagcggata tcagaaggcg
     1741 ctttccagcc ggggccgaaa acgcccaccg gtgcaggcgt cttcgtccgg tagctgctgt
     1801 aggtgcggga gagaatgaac ggcagcgggc cgggcagcgc aaggtccgtc tcgccgggca
     1861 gcaccttcgc ccccagcagc ggatttaccg ggttgcccga agtcatcccg cccggacaca
     1921 ccgagcacgc cacgccggtg ggcgcgccaa ttcttacacc tgccgaaccc tggacaatgg
     1981 gaccgccata ctgagtcata tctccctgac gcgccgctgg ttttccgctc atgattcaat
     2041 tccttcttct gtttattttt aatgctggtt tgttactgaa taccgaacag gtacgggatc
     2101 agtactctct catatccggc gtatcctgct tttcatcagg ggtcttcggt ggggatttcg
     2161 aggctgcaca gttccagtta atcaacagtg agtcaccatt aacctgctcc ttaccctgca
     2221 aatgaatttt tgtgccgttg agaaaaattt gtccgtcctt cgtcagcacc agccttgcct
     2281 taccacagca gagctccaga tgctcaccgg cggagtaaat cgcggtctgc ccggtatcat
     2341 cctttttcgt tttaccaacg gtgaaggtaa cgttatttcc gactttgacg tcataaccca
     2401 gcccgaccct caacgattta tgcaaaccga tctgcgagga ctgcatcaga gccaccgaag
     2461 tgttcataat gccacctacc gtcgtctggt acgccacgcc cacggtcagc gcacgaacaa
     2521 gtccaatcgt ttccacctga acagaaccca ctttaattat ctggttactg cccaccgtct
     2581 ctatctggtt gacacccacc gtctgtatct gattgttggt aaccgcaatc atctgattgt
     2641 tgccaatggt ttcagcatgg ttgtttatca catcagtggt gcggttattc agcacctcgg
     2701 tgttcatgtt cttctgcgcg tggatgtaga cctgttcttt ccctgtcgca tcgtcaaact
     2761 tcagttcatt aaacccgctg cccttatagg ttttcgaacg aatggtcatc tgcgtcttcg
     2821 tccccggcag gctgccgggt gtgcggtttt catggtggta ggtacgcccc ataataatcg
     2881 gctggtccgg gtcgccgttg aggaagtcca caatcacctc ctgacccact cgcggtatcg
     2941 ccaggttgcc aaagccggtg cctgcccacg cctgtgccac acggatccag catgaactgt
     3001 cctggtttga cgggttatag cggtcccagt taaatttcac ccgcacgcgg ccatgttcat
     3061 cacagaagat ttcctcgcct gccggtcccg tcacgacggc gctctgcggg ccgtcgacca
     3121 gcggtttcag caacggctgt ggtcgccatg ttctgtctgc cgggatcacc gcaaaatggt
     3181 tctccagcgc cgtccccgct ccctgccgtc ctggcaccgc ctgtggctgt tcgccgtgca
     3241 gttcacttgc caccacctgc cattcccggt tcaggttcgc ctgcggatgc cccgtcagca
     3301 caattcgtcg tcccggccat atctccggcg agctactcat tccccgcgcg gtttctgcat
     3361 tgtttcgcca gccgtccatc tgccagcggg caaagttctg cccgtgggca cccttgaaac
     3421 gtccggggta gtcatacact tcatactgcg tgcgctggta gtcctggtgc tggccttcct
     3481 gttcaaaacg tccggcccag ccggggcgtt taaaggtgta gtctttggtc accacggaag
     3541 aagggcggat ttgtgcgctg tagcggaact ggctgatgca gagggtgctc acctcggtac
     3601 gggtgttcgg gttccatggg atttcaaaag attcgggcag atggcggact gtgtcgcaca
     3661 gcaccaggct ctggtcggta cttttgtaag catgctcctc ataaaagaag atgccttcct
     3721 ccgccgccat ccggcacagg aaatcgtaat cagtctcacc gtactggaca caaaactcac
     3781 gggaaggatg cggctcgctg aacagcggac tccattcggt caccccgttt tcctgcaaca
     3841 tcgtgccgag gatgcttttg atgtcctcgt tctggaagat acggaagttc tggcgcagac
     3901 cggcacgcca cagcggcggg tgcaccttca tgctgtacag catctggttt ttgtcgttct
     3961 ccccgagttc aaaccaggtc accacgcctt tcacccggcg ctgtacttca tcgccctgcc
     4021 atatcgtcag gtaggccatt ttgtccagca cctgcgcaaa ttcaagggag agaaactgct
     4081 ggctgaccag ggagagatcg agggaaaaga gcgaagagag tgactggttc agatgaaagg
     4141 aaaccaccgc aaaagcatcc ggcggcaggc cgtccacttc cagtgtgaaa cgtaatccgg
     4201 ttgacatagc aacctccgtg aaaatgaata ataatccgca catattgcat gtacaacatg
     4261 tcgggcggat gagataagcg agtcgacatc tggcgttacc ggggaatatc agaaaaatgt
     4321 catggttatg tgatgattta gtctgggatt ttacttcaga gaaacgggtg tctgtttagt
     4381 caacaaaata atcacaaacg caacggatgg gttctcgacg ttattcacga caggctcgta
     4441 cattacagcg agtaataaaa aacctgatat gcaaagtcaa accaatattc ataatgtctt
     4501 tttattcaca acaataaata attcaataac aatcattgaa atgaatgatg gtttgtataa
     4561 ggaatatacg ctaccgcccc accctgataa catgatctgc acattgccat cttaacgtcg
     4621 ttaaacacta gcttaatagt ggatatttca aattaggaat ttattaaatt cacctgatga
     4681 atataataag caaatagcat agaaaataat gacaactccc ccgaggggac catttccaaa
     4741 gcactgcacc accacctggt gccggatgat cttgcttcag tggtaagagt acctgatgca
     4801 ttgttcccaa aatggtgttt tcccctgccc ctccaataat gtgtagctct cac
//
LOCUS       DAPHKZ010000216         4827 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.217, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000216 DAPHKZ010000000
VERSION     DAPHKZ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4827
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.217"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            129..1103
                     /gene="hemB"
                     /locus_tag="RH288_004477"
     CDS             129..1103
                     /gene="hemB"
                     /locus_tag="RH288_004477"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDV4033448.1"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     gene            complement(1210..2061)
                     /gene="tauD"
                     /locus_tag="RH288_004478"
     CDS             complement(1210..2061)
                     /gene="tauD"
                     /locus_tag="RH288_004478"
                     /EC_number="1.14.11.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="HDV4033449.1"
                     /translation="MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKES
                     EALLGFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     KPFYRAG"
     gene            complement(2058..2885)
                     /gene="tauC"
                     /locus_tag="RH288_004479"
     CDS             complement(2058..2885)
                     /gene="tauC"
                     /locus_tag="RH288_004479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease TauC"
                     /protein_id="HDV4033450.1"
                     /translation="MSVLINEKLHSHRLKWRWPLSRQVTLSIGTLAVLLTVWWAVAAL
                     QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVVIGIPVG
                     IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGENSKILLIYLAIFAPVAMS
                     ALAGVKSVQQVRIRAARSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     gene            complement(2882..3649)
                     /gene="tauB"
                     /locus_tag="RH288_004480"
     CDS             complement(2882..3649)
                     /gene="tauB"
                     /locus_tag="RH288_004480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATP-binding subunit"
                     /protein_id="HDV4033451.1"
                     /translation="MLQISHLYANYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQNNVAFGLQLAGIEK
                     MQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     gene            complement(3662..4624)
                     /gene="tauA"
                     /locus_tag="RH288_004481"
     CDS             complement(3662..4624)
                     /gene="tauA"
                     /locus_tag="RH288_004481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV4033452.1"
                     /translation="MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWALAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFAKSAIDAQQPYIANPDAWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
BASE COUNT         1100 a         1403 c         1242 g         1082 t
ORIGIN      
        1 tctattacaa cgatgtcctg gtctctcttt cattctcttc ttgtcaacat cgcgacaact
       61 ttcgtaaaac actcctgccc cgcttcaggt atactgtgca ccttaattcc acaaacatca
      121 ggcagaccat gacagactta atccaacgcc ctcgtcgcct gcgcaaatct cctgcgctgc
      181 gcgctatgtt tgaagagaca acacttagcc ttaacgacct ggtgttgccg atctttgttg
      241 aagaagaaat tgacgactac aaagccgttg aagccatgcc aggcgtgatg cgcattccag
      301 agaaacatct ggcacgcgaa attgaacgca tcgccaacgc cggtattcgt tccgtgatga
      361 cttttggcat ctctcaccat accgatgaaa ccggcagcga tgcctggcgg gaagatggac
      421 tggtggcgcg tatgtcgcgc atctgcaagc agaccgtgcc agaaatgatc gtcatgtcag
      481 acacctgctt ctgtgaatac acttctcacg gtcactgcgg tgtgctgtgc gagcatggcg
      541 tcgacaacga cgcgactctg gaaaatttag gcaagcaagc cgtggttgca gctgctgcag
      601 gcgcagactt catcgcccct tccgccgcga tggatggcca ggtacaggct attcgccagg
      661 cgctggacgc tgcaggcttt aaagatacgg cgattatgtc gtattcgacc aagttcgcct
      721 cttcctttta tggtccgttc cgtgaagctg ccggaagcgc attaaaaggc gaccgcaaaa
      781 gctatcagat gaacccaatg aaccgtcgcg aggcgattcg tgaatcactg ctggatgaag
      841 cccagggcgc agactgcctg atggttaaac ctgctggagc atacctcgac atcgtgcgtg
      901 agctgcgtga acgtactgaa ttgccgattg gcgcgtatca ggtgagcggt gagtatgcga
      961 tgattaagtt cgccgcgctg gcgggtgcta tagatgaaga gaaagtcgtg ctcgaaagct
     1021 taggttcgat taagcgtgcg ggtgcggatc tgattttcag ctactttgcg ctggatttgg
     1081 ctgagaagaa gattctgcgt taattttgtt tcctctcaga aagggggagt taacctgttg
     1141 aaagtacagt gaacgccccc tcaccctaac cctctcccca agggggcgag gggaccgtcc
     1201 actctcgtat taccccgccc gataaaacgg tttatcccca agaatcgtcg cccgatgcat
     1261 aatccgccgc tgtggcaggt aatccgcatt agcatagtgc tgagtcacgc ggttatccca
     1321 aatcgcaata tcattcggtt gccagcgcca gcgcacctga aactccggtt tagtgatatg
     1381 ggcgaataaa aagcctaaca aggcttcgct ctctttctcg ctcacatcaa caattcgcgt
     1441 agtaaagcct tcattcacaa acagcgcctg tttaccgctc accggatgcg ttcgcaccac
     1501 cggatgtagc aacggcggat ttttcgcgac cgcctcgcgc cagcgttgat gttcctcctc
     1561 ggttttgcgg tatttgtatt ccgggaacga tttacggaaa tcatgctccg cacgcagccc
     1621 gctcagcagc tggcggaagg gaacagagag cgcctcatag gccgcaatac cactggtcca
     1681 gagcgtatca ccgccggtcg aaggcaactc tttcgcagcc agaatcgccc ctgcgggtgg
     1741 cgtttcaata aatgtcacat cggtatgcca gttgtcgtta tccggcggat tatcgttatg
     1801 ggtatccagc acgatgatct cgtcaacccc ttcggcatga gggtaaacag ggtgaatatg
     1861 caattcgcca aaacgctggg ccagcgcgcg ttgctgctgc ggcgtaatag cttgatcgcg
     1921 cagaaacacc acctgatgac gcagcaccgc atggtaaagc tgttcaaact gattatcgct
     1981 taacgggcgc gtcaggtcgg cacccgaaat ttgtgcgccg atatacggcc ccagcggggt
     2041 aatgctcaga cgttcactca ttgtacttct ccatgccagg gcgtcaggcg gcgctgtaac
     2101 gcgcgcagac ccagttctaa aagaaaggcg ataatcgcaa tcaccgcgat ccccgccagc
     2161 accacgtcag ttgcgaggaa ctcccccgct gactgaacca taaaacctaa accgcgcgtt
     2221 gcggcaatca gctccgccgc caccagcgta gaccagccca cacccagacc aatgcgtaat
     2281 ccggtgagga tttccggcag cgcgccgggc aaaatgacaa accacagcac ctgcgcacgg
     2341 ctggcaccca gcgaccgggc ggcacgaatg cgaacctgct gcacgctttt cacccccgcc
     2401 agcgccgaca tcgccaccgg tgcaaaaatc gctaaataga tcagtaagat cttcgagttt
     2461 tcgccaatac caaaccagat caccatcagc ggcaaataag ccagcggcgg caccggacga
     2521 taaagctcga ttatcggatc cagaatgccg cgcaccgtcg ggcttagccc catggcgatc
     2581 ccgaccggaa taccgattac caccgccgcg agtagcgcca gcacaatgcg cgtcaggctg
     2641 gcggccagat gctgccacag cgtggcgtcc ataaatccct gcggcccggc aatggtgagc
     2701 agttttgcca gtacctgttg cggtggcggc aaaaacagcg ggctaatcag ttgcagcgct
     2761 gcgactgccc accatacagt gagcaaaacc gctaacgtgc caatgcttaa ggtcacctga
     2821 cgcgagagcg gccagcgcca tttcagccga tgcgaatgca gtttttcatt aatgagcaca
     2881 ctcatgagaa cgcctcccgc tgctcaaata cgcggcttaa aacatattcg cgcatggcga
     2941 tgaattgtgg atcggacttg atgctgcggc tcgactctcc cgcaacaaag cggcgagcaa
     3001 agttgagcgg cagccgctcc agcacgcggc cagggccggg tgaaagcaga accagttcag
     3061 tcgccataaa caccgcttct tctatatcgt gggtaatcaa cagcacctgc ttgcccgtct
     3121 cctgccagag tttcagcagc agggtttgca tctggtcgcg ggtgaaggca tccagcgcac
     3181 caaacggttc gtcgagtaat aacagctggg gatttgccgc cagcgcgcga gcaatgccca
     3241 cccgctgacg ttgaccgccg gagagctgcc agatgtagcg tttttctgct ccttccagcc
     3301 ccactttttt cagcatctgg tgcgcgattt ccagtcgctg cattttctct atacctgcca
     3361 gttgcaggcc gaacgccacg ttgttctgga cattgcgcca cggtagcagc ccttcattct
     3421 gaaaaaccac gccgcgctct gctcccggcc cctcaatacg cttacccgcc agttgaatgc
     3481 tgccgtgctg ataaggcaca aaaccggcaa tcagattcag cagggtggtt ttaccgcagc
     3541 cggacggccc cagcaccacc agtagctcac cgctttccag cgtcaggttg atatcttcca
     3601 gtgccggttt gccgccataa ttggcgtaaa gatgagagat ttgcagcatc tgcgcctcct
     3661 tttattgcac gaagcgcgag gtaacgtact ggctgtaatc attcgctaca gccgggacct
     3721 tgccctgctc tttcaaaaac tgcgcggtgt cgatgatcgc tttgttcacc ggtccggtca
     3781 gttctgccgt ttgttgctgc ggcgtcagat aggtattccc cttcaccagc cccggaacgt
     3841 caccttcagg cacgccgctt aaccgcgcca gtttgctgat gttttccggc tgtttcagcc
     3901 acgcgtctgg gttagcaatg tacggttgct gagcatcgat ggcgcttttg gcgaacgctt
     3961 tcaccacctc aggatgtttc tcggcaaaat ctttgcgcac cacccagacg tccagcgttg
     4021 gcgcacccca ctgcccgacc tgttcagaat cggtcagcac tttgccgtct ttttccaggg
     4081 cgttaaccgc cagtgcccag acataagcac catcaatatc tccccgctgc catgcagcga
     4141 taatcgcggg cggctgcagg ttcacaatct ccacttgccc aggtttaatg ccccagtgtt
     4201 tcagcgctgc cagcaggctg tagtgggtgg tagagataaa cggtacggcg atgcgtttgc
     4261 caatcagatc ctcgggtttg ctgatagttt tctttaccac cagcgcttct gagttaccca
     4321 gttttgacgc cagcaagaag acttcaatcg gcacctgttg gctggctgca accgctaacg
     4381 ggctggaacc aaggttgccg atttgcacgt cgccagaagc cagcgcccgc acgatgctgg
     4441 ctccgctgtc aaacttacgc cagtccacgg ttgctccgct ttctttagca aaggtgttgt
     4501 cggcctgagc cactttcgcc ggttcggctg aggtttgata cgccacggtg acgttcaccg
     4561 cctgtgcctg aaaagcgatg aatgccagtg cggcaagaag tgtgtttcgc gatgaaattg
     4621 ccatgattgt ctgctcccct gtcttgttat gggagcagta ttcaggaata aaaacattca
     4681 ttaaaagaat tagtcgttat cgcacagatg attttattct tagcaaaaaa acggctaagg
     4741 aaagattaaa tatgcaatta ctccgttcta acaattggga aaattactac acttcatttt
     4801 agtgatgcat aaacaaccac attacga
//
LOCUS       DAPHKZ010000217         4760 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.218, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000217 DAPHKZ010000000
VERSION     DAPHKZ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4760
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.218"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(134..1453)
                     /locus_tag="RH288_004482"
     CDS             complement(134..1453)
                     /locus_tag="RH288_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HDV4033453.1"
                     /translation="MDICSRNKKLTIRRPAILVALALLLCSCKSTPPESMVTPPAGSK
                     PPATTQQSSQPMRGIWLATVSRLDWPPVSSVNISNPTSRARVQQQAMIDKLDHLQRLG
                     INTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWF
                     NPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITS
                     IVAEVVSRYPVDGVQFDDYFYTESPGSRLNDNETYRKYGGAFASKADWRRNNTQQLIA
                     KVSHTIKSIKPGVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLD
                     YIAPQIYWPFSRSAARYDVLAKWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMING
                     GVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQSRWGS"
     gene            complement(1584..3119)
                     /gene="gadC"
                     /locus_tag="RH288_004483"
     CDS             complement(1584..3119)
                     /gene="gadC"
                     /locus_tag="RH288_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance gamma-aminobutyrate antiporter
                     GadC"
                     /protein_id="HDV4033454.1"
                     /translation="MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVF
                     FLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIG
                     FIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
                     FAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVE
                     ASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFT
                     VLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNK
                     NGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVL
                     VLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLV
                     VSFLVVLALPFILYAVHDRKGKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMND
                     KKH"
     gene            complement(3275..4675)
                     /locus_tag="RH288_004484"
     CDS             complement(3275..4675)
                     /locus_tag="RH288_004484"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDV4033455.1"
                     /translation="MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCG
                     PVQICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYE
                     FPQPLHDALDKFQADTGIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHK
                     FGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRL
                     GREGYTKVQNASYQVATYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTL
                     YDLSERLRLRGWQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSD
                     HPKLQGIAQQNSFKHT"
BASE COUNT         1220 a         1185 c         1207 g         1148 t
ORIGIN      
        1 attagggatt tatggctgtt taactaagtg tggttaattt gacttaagta agcatgatta
       61 ttagtgggat agtttaagag ggtaacaagc cggtgggtaa agcaccggct tgttacaaag
      121 taagaatggg agtttaactg ccccagcgac tttgcagata gctgaccgct tgttgagtct
      181 gcggtttatt cagatagtcc tcacggaaca agatggtgcc gctaatttcg ggcacagcat
      241 cgttaagatc gagctgcttt ttcagttccg gtacgccgcc gttaatcatc cagtctggct
      301 ctatctttga aggttcaccc actttataga aggcgatacc gatatacagg cgggtcctgg
      361 tcggtttaac gacatccgcc caccattttg ccaacacgtc ataacgcgcg gcactccgtg
      421 agaacggcca gtaaatttgg ggagcaatgt aatccagcaa tccttgttcc acccatcgac
      481 gggtgtcagc gtaggattcg tcataggctg ccgcgcctcg ggtatcggaa ccgagcggat
      541 cgtgtgatcg gttacgccac acgcctgccg ggctaacacc aaattcgact cccggcttaa
      601 tgcttttaat ggtgtgcgat acctttgcaa ttaactgctg agtattgttg cgccgccagt
      661 ctgcttttga cgcaaatgcg cctccgtatt tacggtacgt ttcgttatca tttagccgtg
      721 aacccggtga ctccgtatag aaatagtcgt caaactgcac gccatctacg ggatagcggg
      781 aaaccacttc tgcgactatt gatgtgatcc agtcctgaac ctcagggatg cccgggtcga
      841 ggacaaagcg atcgccagac gttctgatcc agtcgcggtg ttgcacatag acgctcgccg
      901 gttgttgaga cagagtgcta ttcagttccc tgatagtacc gggcttcgta ttaaccgata
      961 cgcgataggg gttaaaccag gcgtgtactt tcatcccacg cttgtgggct tcgtcgagca
     1021 taaattgcag cggatcgtaa cccggatttt caccaatctt accggtcata agatcggacc
     1081 acggcaaaat tttcgatggc cacagggcgg taccgtccgg cttgacctgg aaaaagaccg
     1141 tgtttatgcc gagacgttgc agatgatcca gtttgtcgat catcgcctgt tgttgtacac
     1201 gggcccggct ggtggggtta ctaatgttaa ccgaggaaac cggtggccag tcgagccgag
     1261 aaaccgtggc cagccagatg ccacgcatcg gttgtgacga ttgttgcgtc gtggctggtg
     1321 gctttgaacc tgctggtggt gtcaccatgg actctggagg cgtgctttta caactacaca
     1381 gtaaaagtgc cagtgcaact agtatcgctg gtcttctaat cgttaatttc ttgtttcggg
     1441 agcagatatc catatgtgct ggtttccggt aaacagatgt gcgctcattc tcgtacttat
     1501 ccccgttaag tcaatacgac agcaagcacg aaaaagggag cgatgaatta tcgctccctt
     1561 gtcttataac cattcagaca tggttagtgt ttcttgtcat tcatcacaat atagtgtggt
     1621 gaacgtgcac gcgggtgcag gaagaagtga ccttttggtg cgttctgact gttgattggc
     1681 tccagagtga cgccggtatt tgctttgcct ttacgatcat gaacagcata gagaataaag
     1741 ggcagggcaa gtaccaccag gaaactaaca accagtaatt caacatacat atcggtagaa
     1801 tcaccctgga tgttatccgg cggcaggaag gaaacaataa acgccataat tgaagtcagc
     1861 agaccgacaa ttgccacgac cagtttcacc cctttaccac cagggatatt aaatgtgcgt
     1921 tttaagtcag gatgtttaag aaccaacaca atgtagccaa taaacagcat gaaataagca
     1981 cacagataaa tcaccaccgt cagcgccagt gcgatcagga aggacatgtt gttaccgcca
     2041 ccggtattag tgaggatgat caacgcgata gaagtaatca ccagctgcga aatgaccagc
     2101 gttaccggta cgccattttt gttcatttta gcgaatgccg ctggcagcag gtttttctgc
     2161 gctgtgacat acatcccgcg agaaggacca acaatccagg aggcgatttc cgccagaaca
     2221 cccagcaaca gcagtgcgga gatcacgcga accgtccact caatttccgg tgccacatgg
     2281 gacatcagaa cggtaaaggt ttgcattacc cctgcggaga ggttgatttc attacccgga
     2341 atgaccatcg caatagacaa accaccaaca gagcttaagc agattgccgc caccatcagc
     2401 agtaacatag ccaacggata gtcgcgccct gggttgctca tttcattgac gtgggttgcg
     2461 gatgcttcta cgcccatata actcaaaatg aaggcaacaa atactaccaa ggtgcccact
     2521 ttagagaagt cagggaagaa ggtcttcgaa tccatttcga tagcaacggg ggcaccggag
     2581 tgcagataaa tagccgctaa tgcgatcaaa ataaatgcag gtaacaggat accggcgaag
     2641 aagccaactt tagcaattcg cgccgtgtat ttcgtgccac caaactgcgt taatgccagc
     2701 gcccaaagaa tgatgagtgc tgcaatagtt ttggtaatgg ggtcttcatt cagcgctggc
     2761 catttcagga tgtaggagag tgcccctaac acgaaataga gcatcggaat aaaaccaatg
     2821 gcgatttgca gatagccaaa tgagatcgct gcaaatcccc atctcggccc cagagtattt
     2881 gatacccagg cgaagacacc accttcttcc cagccgtcga cggtggccat ttccgcagca
     2941 caaagtccca cgggaataaa ccataaaatc ccgcctaata gcaggaagaa gactaatgaa
     3001 aagcccgatg ttgcgaaggt agggtattca taaacagcca ttaccatcga tgccgttatg
     3061 gcaaaaaagc cgagtaatgt gagctgctta gctttacctg tctgtactga tgtagccata
     3121 ttatccccct aaaacggtat tcctgtcgga accgcacctg ttttgttctg aagcgtattc
     3181 agaacaatat tttccgttgc taatgccagt gaacagactt tggaaattgt cccgaaacgg
     3241 gtgcgtttcg ggacaccgtt accgttaaac gttatcaggt atgtttaaag ctgttctgct
     3301 gggcaatacc ctgcagtttc gggtgatcgc tgagatattt cagggaggct ttgtagtctt
     3361 ccagcaacag ttcagcaaag tccatttcga agccgcgacg acacataatg cgcatcacca
     3421 cgatgtcggt ggcttcaccg ccgagagtga aggccggaac ctgccagccg cgcagacgca
     3481 gacgttcaga gaggtcgtac agggtgtatc ccggatcttc accatctttc agtttgaagc
     3541 aaaccgccgg gatgccttcg tccgggcgac cggtacagat gaactcatac ggccccagtt
     3601 tggcgatctc atccgccaga taggtagcga cctgataaga ggcgttctgt actttggtat
     3661 agccttcacg accgaggcgc aggaattcat agtactgtgc aatcacctga cctgccgggc
     3721 gggagaagtt gatggcgaaa gtcccaatct gaccaccgag atagtcaacg ttgaacacca
     3781 gttcctgcgg cagcgcttct tcgtcacgcc agataaccca gccgcagccc agcggagcca
     3841 gaccgaattt atggcctgaa gcactgatcg atttcacacg cggcaggcgg aagtcccaga
     3901 cgatatccgg ggcgacgaac ggtgccagga agccaccgct ggcggcgtcg atgtgcatgt
     3961 cgatgtcgat accggtgtcg gcctggaatt tatccagcgc atcgtgcagc ggctgcggga
     4021 actcatagtt accggtgtag gtcacgccga aagtcggcac cacgccgatg gtgttttcgt
     4081 cgcaggcttc aatcatgcgt ttcgggtcca taaacaactg accggggcgc atagggatct
     4141 cacgcagctc cacatcccag tagcgagcga atttatgcca gcagatttgc accggaccgc
     4201 acaccaggtt tggtttatcc gttggtttgc ctgcagcttc catacgcttg cgccaacgcc
     4261 atttcatcgc catcccgcca agcatacagg cctcggaaga accaatggtg ttggtgccaa
     4321 cggcctgacc atttttcggc gcaggcgcat gccacagatc ggcaaccata tttacgcaac
     4381 gcaggtcgat ggctgcggat tgtggatatt cttctttgtc gatccagttt ttgttaatgg
     4441 ataaatccat caatttgtgg acattttcgt cgtcccaggt ctggcagaaa gtggccaggt
     4501 tctgacgagc gttgccatca agatataatt cgtcattgat aatctggaat gcgacatcgt
     4561 cgcgcatttc gtgcagcgga aaacgttttg attctgcgat agtggaaata gacttcgccc
     4621 caaaacgtga atcgagtagt tccgacctta aatccgttac ttgcttctta tccattttaa
     4681 actccttaaa atgattggat cgcattaaaa aagtaggatt tatcgataaa gtaagcaagt
     4741 gcaaaggact cgtgtttaaa
//
LOCUS       DAPHKZ010000218         4614 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.220, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000218 DAPHKZ010000000
VERSION     DAPHKZ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4614
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.220"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            647..898
                     /locus_tag="RH288_004485"
     CDS             647..898
                     /locus_tag="RH288_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001315600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDV4033456.1"
                     /translation="MKTTNSILRVIASVIAAGQNQISITELVSLSGISRQSVKRAIQI
                     LEQTGQITVTRTTTNGKREANTYYLPDQDLGGGCRSTLS"
     gene            complement(1294..1449)
                     /locus_tag="RH288_004486"
                     /pseudo
     CDS             complement(1294..1449)
                     /locus_tag="RH288_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219394.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(1790..2737)
                     /locus_tag="RH288_004487"
     CDS             complement(1790..2737)
                     /locus_tag="RH288_004487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004215186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV4033457.1"
                     /translation="MRRMTILVLFLLVVLTWGTTWLAMRIAAETIPPVFATGMRFMFA
                     APFLISIAWLRKIPILFPPGQRLFQLVICIFYFSIPFSLMIYGETYVSSGLASLIFAN
                     MPVAVLIASSLFLKEKTNSMQIMGLTIAIVALAGILLEESKTSAESHWQGIIALVSAV
                     IIHAIIYTQCKKRSCTVSVVTFNALPCFLAGLILSATGWFFERPEVSTFSVYSILATL
                     YLGAFAGVFGILCYFALQQKASAFQASLVFLIFPLIAVSLESCIYGYGISTQSMLFII
                     PLVIGLFLTLFLRRVPVTNGHRDSSSQKANEIAEHAENS"
     gene            complement(3138..3211)
                     /locus_tag="RH288_004488"
     tRNA            complement(3138..3211)
                     /locus_tag="RH288_004488"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            complement(3538..4552)
                     /locus_tag="RH288_004489"
                     /pseudo
     CDS             complement(3538..4552)
                     /locus_tag="RH288_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611477.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1374 a         1068 c          991 g         1181 t
ORIGIN      
        1 atggctgaaa gcaggtatgg cttagcaggg ctggggatag gtaaggtgaa atctatcaat
       61 cagtaccggc tgacgccggg cttcggcggt tttacttcgg tatcatatgc aacaacggag
      121 tgccgccttc catgccgcta gcgcggcata tgttggtggc tgtgtctgaa aggttatata
      181 ctctgcataa aaccagacaa cacgcagatt accaggcgaa tatcgatact ctgactcgtt
      241 atacccatgc gtgcggcatc ataaaacctg caattgtcct ttattgaatg aaaggggggg
      301 gcatgtatag gaaattgaaa aaacaagcga tactgcggtc tggttaaatg gcgtgatgaa
      361 taattgagca atcctgcagc attaggagcg ctaatatgca gctattttta tttattggcg
      421 tcaaaaatta tatagggaaa tttcccccat ataataccct gagagccgca tcacgtctgg
      481 cctgagcgac atccttaaga tgttaataag aattaaaatc ttaaggagaa aaagaacgcg
      541 cgttgctcga tatctttttc tttgaactac aattcgatga ccttcggacg acatccagac
      601 agccgcaaga aaaaacatgg cctagcagag ataaggggcg ctgacattga aaacgacaaa
      661 ttcaatccta cgtgtaatcg ccagcgtcat tgctgccgga caaaatcaaa tctcaatcac
      721 tgaactggta agcctctccg gtattagtcg acagagtgtt aagcgggcaa ttcagatact
      781 ggaacagaca gggcaaatca ccgttaccag aacaaccacc aacggcaagc gcgaagccaa
      841 cacctattac ctgccagacc aggatttggg aggcggttgc cgttcaacat tatcttaacc
      901 acggctgctg cctggagttt acggggtctg aagcccaacc gtacgaaaac gtactataag
      961 ggcttccccg gcatgtcaac gccagttttt atgtttttgc ctgcttgacg tataggaatt
     1021 tgaaaaacca ggcgtcctca ttaaaaataa agggaaaaga ctgcggtact ataaacggtc
     1081 ataatgaatc gtcatcgatt cggcccctga tgaaagacgc ttgtgaggtt cttgttcgct
     1141 aagcggatat gtatatcctg tacgttttgc agatattcct cacggggtat aaccctttat
     1201 catcaacgag ttgcaggtca aatggtcata ctgttgcagc gtgctttagc tggctgaata
     1261 cagtctgaaa tcataaccgt aatacaatga tgctcagtac agccttgcat ttttggcggc
     1321 gatggccaca actgcgcgcc agtatcctct gcgctcgacc agtgaacagt cccaacgact
     1381 gaatgagtca gtccttttct cagcaccagt cagtactgaa cgagccccct gtaccagaag
     1441 cgttcgcagc ttgccgaaat aaccttgcct ggttgtgagc ttcggaacat gcctccatcc
     1501 cgataacaca gggctgcaaa tcagcaatca gctcaggaag cccaattcgt gatattctgg
     1561 tgttaaccaa agccgtttac catcctggtc aataccgtga acagtaagca tatttttagc
     1621 tagatcgaca cgatagtagc aatagtcata acgaatccat ccggactatg cttaccctca
     1681 taattgcaca agagttaacc tggtgcatat tcaggggaag ccccttccat ccgttaagtg
     1741 taatggccta cattaacaac tgaaaacgaa aagtcttttc ttcaagtttt caggaattct
     1801 ccgcatgttc agcaatttca ttagcttttt gtgatgaact atctctatgt ccgttggtta
     1861 caggcactcg acgtaagaac agagtcagaa atagccctat aactagcggt ataataaaca
     1921 gcattgattg agttgaaatt ccatatccat atatacagct ttcaaggctt accgcaatca
     1981 atggaaaaat aaggaaaaca agagaagcct gaaaggcact ggccttttgc tgaagggcaa
     2041 agtagcacaa tattccaaaa actccggcaa aagcaccgag atacaaggtg gctaatattg
     2101 agtacacaga gaaggtcgat acctcgggtc tttcgaagaa ccatcctgtc gcagaaagta
     2161 tcaatcctgc cagaaagcac gggagcgcat taaacgttac cacagagaca gtacaacttc
     2221 ttttcttaca ttgagtatat attatggcat gaatgattac cgcagaaaca agagcaataa
     2281 tcccctgcca gtgactctct gcacttgttt tcgattcctc aagaaggatg cccgccagtg
     2341 caactattgc gatagttaaa cccataattt gcattgagtt cgttttttcc ttcaaaaaca
     2401 aagatgaagc tatcaaaaca gctacaggca tattcgcaaa tataagggat gcgagtccgg
     2461 aactgacata ggtttcacca taaatcatta atgagaaagg aatggaaaaa taaaaaatac
     2521 aaattacaag ctggaataag cgttgtccgg gtggaaataa aattggtatt tttcttaacc
     2581 atgcaatact gattaagaat ggtgcagcaa acataaacct catcccggtt gcaaaaactg
     2641 gggggatagt ttcagcggct attcgcatag ccagccatgt ggtcccccaa gtcagtacaa
     2701 caagcaggaa taataccaaa atcgtcattc tgcgcataag attcctctac tatagaagat
     2761 aaaaaaaacc gccgagacgg cggttaactg catgagatta caggtattga taatctgaga
     2821 tgtcgggtgc ctcccgaaga atatctgatt ggttacagat attctgtggt tttcccgcca
     2881 aacaattcta caaaccaccc tcgcactgag gaacatctct tttcgttata ttaacaacat
     2941 tgagatagtg catcactggc acctccagga aattgctaca ccctccagca atgcactatc
     3001 ctcatattga taaaaaataa gcactggaac tgtagttaac aaatataagt tatcacagaa
     3061 caggatgata tagggtaatg aaaatatccc acacaatttg tgtcagtgcc caaaaacacg
     3121 tccaactgct tttctttagc gggtggtggg aatcgaaccc acatcatcag tcagaaaaaa
     3181 actgaggtga ttaccattat acgatacccg cacaacatat taaaaatgaa catattattt
     3241 atatgtcaat cagcattatc cttgccttcc cggcaatcca ctctcaaggt ttgtaaaaca
     3301 taaaaaaaag ctggtttcac acttccattt tatgaacgtg ctcatgattt tctctttgga
     3361 gcacgtgctt gcgcaaccag cattaaaata aaatgcaagc gtcggtatag ccaagttggc
     3421 atcggggatg aatgccatga actttcgtaa agaagattaa atcaatgtac atttgtgttg
     3481 tttgctaatt gtgcacaagt ctgccaccag atgaccagcc cccaggatta gatgcagcta
     3541 tctgttagta atgtcgccat tccaccacca tgctgcaaac tttgatggca tctgataatt
     3601 cagtactgaa tgtggatgat actcgttata attctgtcgc cagccataat gactttcctt
     3661 agcaaacgac atccctgaac ctgtgctcat tcagacattc atcgcgaaat agcccgttaa
     3721 agcgctcagg aaatatgttc tgcgttagtt tgtccgactg gattctgttc aggtcttatc
     3781 gtcaccggat agccttgaaa cagtgcaatg cagtccagaa tacgcgtgac ctgaacacct
     3841 gaaatcccga atactgtggt tattgttaaa cactccttcg taaatgtcgt ccacgcaggt
     3901 caggcatttg attctgcgac cagtaaccag cgtgtccatg gcaaaatcca tcgacttggt
     3961 caggttttga acctccggac agagttacgg caagcgttct tgaccagccc tttacgacgt
     4021 catctgcatt tcacgccctg gcagctcaga tgataaagat ggtaaacgtg cttgcgatta
     4081 gcatgagccc cttcacggtg cagtactacc agatgtggcg gttgccaaaa cgtctgcgct
     4141 ttagtgacag catcaatgat gtgtcctgct caatacgtat cagaatacgt attgagcagg
     4201 actctgagtc tcatcgcgca gatcgacagg gacaagtcag cctgcagcaa gacgttgcgt
     4261 cagagcagcc gtatcacata taaaacggtg cctcgcttcg ggtctgccat cagtacttta
     4321 gccctggagt tacctgaagc gcgtccttat cgggatagct tgggtaagca acacctggag
     4381 tctgcgccct cttcctcaag cgacttcagg ggcttgacct cgggtatctc cataccacta
     4441 tacttcttac accaagtata aaagagtgca tcggacatgg atgcgcttgc tacagagctc
     4501 acgctcctcc ggctatactg atactctgtt tgccggaaaa atgctttttc atggggatgt
     4561 cctcatgtgg actatgaaga cattgctgac accaagatgc atcaatcaac gaag
//
LOCUS       DAPHKZ010000219         4496 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.221, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000219 DAPHKZ010000000
VERSION     DAPHKZ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4496
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.221"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            14..907
                     /locus_tag="RH288_004490"
     CDS             14..907
                     /locus_tag="RH288_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV4033458.1"
                     /translation="MNIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQALEQQ
                     IGARLLARTNRSVLLTAAGKQFLADSRQILSMVDDAAARAERLHQGEAGELRIGFTSS
                     APFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPESLEH
                     AVIVHEPLMAMIPHDHPLANNPNVTLAELAKEPFVFFDPHVGTGLYDDILGLMRRYHL
                     TPVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWP
                     KHHEQSPAARNFRIHLLNALR"
     gene            1042..2262
                     /gene="mlc"
                     /locus_tag="RH288_004491"
                     /gene_synonym="dgsA"
     CDS             1042..2262
                     /gene="mlc"
                     /locus_tag="RH288_004491"
                     /gene_synonym="dgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor Mlc"
                     /protein_id="HDV4033459.1"
                     /translation="MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALR
                     DLSSKLVVEESQELALKDDLPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTE
                     NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILE
                     LAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            2387..3082
                     /gene="bioD"
                     /locus_tag="RH288_004492"
     CDS             2387..3082
                     /gene="bioD"
                     /locus_tag="RH288_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HDV4033460.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGS
                     KETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANL
                     TEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLA
                     MLRSVLAVDRVTV"
     gene            complement(3035..4327)
                     /gene="clcB"
                     /locus_tag="RH288_004493"
                     /pseudo
     CDS             complement(3035..4327)
                     /gene="clcB"
                     /locus_tag="RH288_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296088.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
BASE COUNT         1138 a         1113 c         1212 g         1033 t
ORIGIN      
        1 agatgtttta aatatgaata ttgaacttcg tcatctgcgt tactttgttg ctgttgcgga
       61 agagctgcat ttcgggcgcg ccgctgcccg cctgaatatt tcgcaaccgc cgctaagtca
      121 gcagattcag gcgctggagc aacaaattgg tgcccgactg ctggcacgaa ccaatcgcag
      181 tgtattgctg acggcagcag gaaaacagtt tcttgcagat agtcggcaaa tcctgtctat
      241 ggtggatgac gctgccgctc gcgctgaaag gctgcatcag ggtgaagcgg gggagttgcg
      301 cattggtttt acttcgtcgg ctccttttat tcgggcggtg tccgatacgt tatcgctgtt
      361 tcgccgtgat tatcctgatg tccatttaca aacccgcgaa atgaacactc gcgagcaaat
      421 cgctccgctc attgaaggaa cgctggatat gggattgctg cgtaacacag cgttaccgga
      481 gtcgcttgaa cacgcagtca tcgtccatga accgcttatg gcgatgatcc cgcacgatca
      541 tcccctggca aataacccga atgtaacgct ggctgaactg gcgaaagaac cctttgtctt
      601 ttttgatccg cacgtcggga cagggctgta tgacgatatt ctcgggctga tgcgacgtta
      661 ccatttgacg cccgtcatca ctcaggaggt gggcgaggca atgaccatca tcggtctggt
      721 ttccgccggt ctgggtgttt caattttgcc tgcgtcattt aaacgtgttc agctcaacga
      781 aatgcgctgg gtgccgattg ctgaagagga tgcggtttct gaaatgtggt tggtctggcc
      841 gaaacatcat gaacaaagtc cggctgcgcg taactttcgt attcatctgc tgaatgctct
      901 caggtgaggg aaatttcagc gaaaaagccc gaaaaatgtg ctgttaatca catgcctaag
      961 taaaaatttg acgacacgta ttgaagtgct tcaccatagc ctacagatta tttcggagcg
     1021 cgaaaatata gggagtatgc ggtggttgct gaaaaccagc ctgggcacat tgatcaaata
     1081 aagcagacca acgcgggcgc ggtttatcgc ctgattgatc agcttggtcc agtctcgcgt
     1141 atcgatcttt cccgtctggc gcaactggct cctgccagta tcactaaaat tgtccgtgag
     1201 atgctcgaag cacacctggt gcaagagctg gaaatcaaag aagcggggaa ccgtggccgt
     1261 ccggcggtgg ggctggtggt tgaaactgaa gcctggcact atctttctct gcgcattagt
     1321 cgcggggaga ttttccttgc tctgcgcgat ctgagcagca aactggtggt ggaagagtcg
     1381 caggaactgg cgttaaaaga tgacttgcca ttgctggatc gtattatttc ccatatcgat
     1441 cagtttttta tccgccacca gaaaaaactt gagcgtctaa cttcgattgc cataaccttg
     1501 ccgggaatta ttgatacgga aaatggtatt gtacatcgca tgccgttcta cgaggatgta
     1561 aaagagatgc cgctcggcga ggcgctggag cagcataccg gcgttccggt ttatattcag
     1621 catgatatca gcgcatggac gatggcagag gccttgtttg gtgcctcacg cggggcgcgc
     1681 gatgtgattc aggtggttat cgatcacaac gtgggggcgg gcgtcattac cgatggtcat
     1741 ctgctacacg caggcagcag tagtctcgtg gaaataggcc acacacaggt cgacccgtat
     1801 gggaaacgct gttattgcgg gaatcacggc tgcctcgaaa ccatcgccag cgtggacagt
     1861 attcttgagc tggcacagct gcgtcttaat caatccatga gctcgatgtt acatggacaa
     1921 ccgttaaccg tggactcatt gtgtcaggcg gcattgcgcg gcgatctact ggcaaaagac
     1981 atcattaccg gggtgggcgc gcatgtcggg cgcattcttg ccatcatggt gaatttattt
     2041 aacccacaaa aaatactgat tggctcaccg ttaagtaaag cggcagatat cctcttcccg
     2101 gtcatctcag acagcatccg tcagcaggcc cttcctgcgt atagtcagca catcagcgtt
     2161 gagagtactc agttttctaa ccagggcacg atggcaggcg ctgcactggt aaaagacgcg
     2221 atgtataacg gttctttgtt gattcgtctg ttgcagggtt aacatttttt aactgttcta
     2281 ccaaaatttg cgctatctca atttgggcca ggaaagcata acttagactt tcaaggttaa
     2341 ttattttcct ggtttatatt tgtgaagcat aacggtggag ttagtgatgc tgaagcgttt
     2401 ctttattacc ggtacagaca cttctgtagg gaaaacggtg gtttcccgcg cattgctaca
     2461 agcgttagcc tcccagggaa aaacggttgc gggatataaa cccgtagcga aggggagcaa
     2521 agagacaccc gaagggctgc gtaataaaga tgccctggtg ttgcagagtg tttcaaccat
     2581 cgaactgcct tatgaagcag ttaatcctat cgcgttaagc gaagaagaaa gtagcgtggc
     2641 gcacagttgc ccaatcaatt acaccctcat ttcaaacggc ctggcaaacc tgaccgaaaa
     2701 agtcgatcat gtcgtggtag aagggactgg cggctggcgc agtctgatga atgatttgcg
     2761 tccactctct gaatgggtag tgcaggaaca actgccggtg ttgatggttg tcggtattca
     2821 ggaaggttgc attaaccatg cactgctaac agctcaggcg atcgccaacg acgggctgcc
     2881 gctcattggc tgggtggcta accgaatcaa cccaggactg gcgcattatg cggaaatcat
     2941 tgatgtgctg ggtaaaaaac ttccggcacc gctcattggt gaactgcctt atctgccgcg
     3001 cgccgaacag cgtgaactgg ggcaatacat ccgcttagct atgctgcgca gtgtgctggc
     3061 ggtagataga gtcacggtgt aacgtccgcg aaattaccga cgcaattacg caggcaatca
     3121 ataaaccggg gagtagctga tactccccgg tcatttcaca tatcatcaac gtcgacataa
     3181 tcggcgcgtg cgtggtcgcc gccaacagtg tcgccatccc ggtcaatccg agtaaaagtg
     3241 taatttcttc gccatcaggg aaccataatc ccaggctacg accatacaac atgccaatgg
     3301 caagaccgat aaatagcgtc ggtgtaaaga ccccaccggg tgcgccggaa ccgctactcg
     3361 ccagcacggc acacagttta caaaggaaga tcccggcaat gatcattaac agtggtgggg
     3421 cggttaaaaa ggattgtacg gtgctatagc cgttgcccca cactgcaggt gtgaacaggg
     3481 aaagcagacc cacgatcaac ccgcctagtg ccagttgcta gggcggcgca agtttgagac
     3541 tcacaaatcc acgatgacag gcgttcatta acgttaacaa cagtggtccg cacagacctg
     3601 ccagcacacc tgtactgata atcagcgcat agtcacgagc ctgaaccgtc actgagagtt
     3661 gtacgttgta gagtaacgcg tcgctatgat taatcagatt gctaaccagc aatgccacga
     3721 cggcggaaat aatcaccggg ccgagagagg ccaacatcat agtgccaaac agcacttcgg
     3781 ctataaataa actgccagca agcggggcac gataggccgc agccattccc gccgcggccc
     3841 cacaggcgat ccataatttc cactcctggc gtggcgtaaa acgttgggca aaacaggagg
     3901 cggcaagggc agctaaaaga atcatcgcac cttcgcgacc aattgcactg ccgctggtta
     3961 ctaccagcag agaggcaagc gatttaacca ggcttgctgc gtaatcgaac tgtccatcgg
     4021 tttgcaacgc ttccatataa tcggtcggcg catgagggcg ttgttgggta aatttctgcc
     4081 agcccatcag caacaaaccc gccgccagtc cgccgagcgc cggagttagc aaccgtcgcc
     4141 agggggaaag gtttgtcgct gcattgacca gactgccgga gtcattattg aggaacaacc
     4201 actccagtag cagcatcgca tgacgaaacc cggcaacggc aaaggccgcg agaataccga
     4261 cgactgttgc gataagcaga cggcggaaca tagtgcgcag atccggatag atgtgtagat
     4321 gatgcatgag cagaaatggg caatgaaaca cgggcgacta ttttgcggca aaagaggcca
     4381 gccgcaaaag cagtgcgtgc tttaagagat aaaaaaacgt gacactgtaa cctattattg
     4441 ccggattgcg cgtaatcgtc accatccggc aatattacgg tgatcctatc gaaaca
//
LOCUS       DAPHKZ010000220         4494 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.222, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000220 DAPHKZ010000000
VERSION     DAPHKZ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4494
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.222"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            377..640
                     /locus_tag="RH288_004494"
     CDS             377..640
                     /locus_tag="RH288_004494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HDV4033461.1"
                     /translation="MPYHKDRNLYFLSSSMVAQAGQALAWPVSDDAGIPTPVWAITNE
                     RRNSVIAFLVVIGDLCYVTSTDTETPGHHSVGRHVSRAINKPA"
     gene            558..845
                     /locus_tag="RH288_004495"
     CDS             558..845
                     /locus_tag="RH288_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HDV4033462.1"
                     /translation="MSPQLIQKLPAITLLEGMFPELSTNQLKVCVFYAMGVPYDAIAQ
                     NCRLSPETVRTYLKRSLKNLNLEGYDALRSAVLMRTFVFMISNTAKENEKM"
     gene            1287..1820
                     /locus_tag="RH288_004496"
     CDS             1287..1820
                     /locus_tag="RH288_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001303319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusG"
                     /protein_id="HDV4033463.1"
                     /translation="MNIEHLNNRNWYLAQYNTAGKNRESLFSWLNEQNVVPWTPLITR
                     KIRRADSRCCYRERIFAIFPGYFFILANFDIHPVSALRRHSAFIDFVKFGGEIKPVNK
                     DIVDGLMKIYPDPVLNPGAREELNAASSIWLTKAQYQYLLRMENTLQPESRISLLLEL
                     VSNAEHHGFMERLVNIP"
     gene            2074..2757
                     /locus_tag="RH288_004497"
     CDS             2074..2757
                     /locus_tag="RH288_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraC"
                     /protein_id="HDV4033464.1"
                     /translation="MTTTEHPVRQLLWCALNALKTAQENHNITSETGLRHYLLEWLSG
                     ASRHPEFRSLPGEIMALKALTEKDRNIPIIGTLNTLFLSSATVGECPLFRFRAALGKL
                     QKAGWRTYVCPWPERVFNESIERACSGKRHLLQLSRTEECFLPTGDMRAPVTLQLITP
                     LHRKTMQLLEAAELIFSDEGFQVVRGYEHQFGIERRETLFHTLFIGLPSLPEDVWGAT
                     QEQTTITLH"
     gene            2771..3337
                     /locus_tag="RH288_004498"
     CDS             2771..3337
                     /locus_tag="RH288_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraD"
                     /protein_id="HDV4033465.1"
                     /translation="MKLQYRIPLAIYSVWCIIAILLCKDGLYQMNIWTLVEILGMIAL
                     PLLVRPFFILLRIIFRKNSFKTKDMSDNHTVCVFLSALADTSSKKAIKKHFKQLLEKL
                     PPLLRQKKRIYMKSHLLTEARTQKLICSLRRKGLDVTAERRESAMNSVMFRILIVSRI
                     LSQWKVPHINPRCGIVILTLKNDSGNRE"
     gene            3605..3859
                     /locus_tag="RH288_004499"
     CDS             3605..3859
                     /locus_tag="RH288_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilI type IV pilus biogenesis protein"
                     /protein_id="HDV4033466.1"
                     /translation="MPQQHPGRLQVLVVDTHCKRKLFSTKTQTDPDELARRFCTPDNC
                     LVVVLCNNRFLFRLERAPGSHCRWRKGSRSRHQHLQDWLS"
     gene            3902..4354
                     /locus_tag="RH288_004500"
     CDS             3902..4354
                     /locus_tag="RH288_004500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pili assembly chaperone"
                     /protein_id="HDV4033467.1"
                     /translation="MSFLFKLTIAILIVFAILFPILISSDNKLSALFWKIPKDFWVFL
                     IIMYGAIITVVFIESSEQARIRRQQYLQQYKMPNEIHENVVIENSIISRETTDDESDI
                     NTLYLDSFKSKNNCKSFETNSNLLDKNGKPVEIMVCDVQELHFFVPKN"
BASE COUNT         1248 a         1074 c          977 g         1195 t
ORIGIN      
        1 atcgtaaata gaatgattct tagatgataa aaccatttgt tacacaaccc gccaattgtg
       61 taacaacagc ctctacaaga gcatatttgt tcatatgttc gtcagaactg cggattgtct
      121 ggacgagggt cagacaccgt ttcgtgcata tggaccagca tgttcgaacg ccacaaagca
      181 gaagcatcat gcctggatcg cttcggcgcg gagcgttaag ttttgacgct tttttgtatg
      241 ttttttaagc tgttagttga ctcggtgcgt tatactaagt accctttact ggtcacaggc
      301 aaaactgtga tcgggcgtag gaacccgcgt agtcatcgtc ggcgcagaag ttaatttctt
      361 catttggcgt cgttttttgc cataccataa agacaggaac ttgtatttct tgtcgtcatc
      421 tatggtagct caggcggggc aggcattagc ctggccggtt tccgatgacg ccggtattcc
      481 tacccccgtc tgggctatca ccaatgagcg taggaactcg gtgatagcgt ttttagttgt
      541 catcggagac ctttgctatg tcacctcaac tgatacagaa actcccggcc atcactctgt
      601 tggaaggcat gtttcccgag ctatcaacaa accagcttaa agtctgcgtt ttttacgcaa
      661 tgggtgttcc ttacgacgcc attgctcaga actgtcggct ttctcccgaa acggtacgaa
      721 cctacctgaa gcgaagcctg aagaatttaa atctggaagg atatgatgca cttcgctctg
      781 ctgtgctgat gcgaactttc gttttcatga ttagcaatac agctaaagaa aacgaaaaaa
      841 tgtgaacagg tgtccccatt aaaggggaca ctttcatgga aattgcattt tgcactttac
      901 aggcgatccc aaattgataa acataaacac caagcacaag ttactttaat aaagcaaatc
      961 acttcagacg gtgtcccagt tatttgtatc tggctcatgc ccgatatatg gcgaccttac
     1021 tctgaactga cgtgctgatg ttttatttcg cgtatcacaa tactgtgcca ctgtattgct
     1081 gatattagtg cttagccgtt ctttatctgt gagttcgcca aatcaccgat acagaacgta
     1141 ctagagtctg ctggttatat gcctgtcaga actgcagttt atccagatat gggctggaca
     1201 ctgcttcaga catatgattt agcatattcg cctgacatcg caaaatcgtc catcatggat
     1261 cggttttgcg cggagcgttg aacttcgtga atatagaaca cctgaataac cggaactggt
     1321 atcttgcgca atataataca gccggcaaaa acagagaatc tttattctca tggctgaatg
     1381 agcaaaacgt cgtaccatgg actccattaa taacaagaaa gataagacgg gcagactcca
     1441 ggtgctgtta ccgtgaaaga atattcgcta tttttccagg gtactttttt attctggcta
     1501 attttgacat tcacccagta tcagcattac gtcgacatag cgccttcatt gatttcgtga
     1561 agtttggcgg tgaaataaaa cccgtcaata aagatattgt tgatggatta atgaagattt
     1621 acccggaccc tgtgctaaat ccgggagcca gggaagagct gaatgcggct tccagcatat
     1681 ggctgacaaa agcacaatat cagtatctcc tcagaatgga aaatactctc cagcctgagt
     1741 cgaggatatc cctgctcctg gaactggtat caaatgccga acatcacggc tttatggagc
     1801 gccttgtaaa catcccatag ccagtatttc ccggccttcg ggccgggctt ttttcaattc
     1861 aagagaatat tccggagtga agcctgcacg aagccatccc caccatggac tccccctgtc
     1921 ttttgatgga accgtgtatt tcttaatggc gaaagaaata aaaggcttca ccccagagta
     1981 ttgattcgtt ttatcaaagg ccggcccgtg ccatcacgtg tggcggagag aacggatacc
     2041 ggtcttcttt tcatctcaca gtaggacatt cgcatgacca cgacagaaca tcccgtgcgc
     2101 cagttgctct ggtgtgcact gaatgccctg aaaacggcac aggaaaacca caatataacc
     2161 agtgaaaccg gattacggca ttacctgctt gaatggcttt ctggtgccag cagacatcct
     2221 gagttccgta gtctccctgg cgaaatcatg gcgttaaaag cattgaccga aaaagatcgc
     2281 aatattccca tcatcggaac gctgaatacg ctctttctca gctctgccac tgtcggggaa
     2341 tgtccgttgt ttcgttttcg ggctgcactg ggtaaattac agaaagcagg ctggcgcaca
     2401 tatgtctgcc catggcctga gagggtgttc aatgaatcca ttgaacgggc ctgttccggg
     2461 aaacgtcatc tgctacaact aagtcgcacc gaagagtgtt ttctaccgac aggcgatatg
     2521 agggcaccag ttacgttgca gctgatcact ccactacacc gcaaaactat gcagcttctg
     2581 gaagcggcag agttaatatt ctccgacgaa ggatttcagg tggtgagagg atacgaacat
     2641 caattcggga tcgaacgcag agaaaccctc tttcacacct tatttatcgg gctgcccagc
     2701 ctgccagaag atgtctgggg tgcaacacag gagcagacga ctatcacatt acactgagga
     2761 agagcaatac atgaaactcc aatatcgtat tccattagct atatatagcg tctggtgcat
     2821 tatagcgatt ttgctctgca aggatggctt gtaccagatg aacatatgga cgctagtaga
     2881 gatattgggg atgatagctc tcccgctgtt agtccgtccg tttttcattc tgcttagaat
     2941 aatatttagg aaaaatagtt ttaaaaccaa agacatgtct gacaatcaca cagtatgtgt
     3001 tttcctgagc gcactcgcag atacttcctc aaagaaggcg ataaaaaaac acttcaagca
     3061 attactcgaa aagctgcccc ccttattacg ccagaagaaa cgtatctaca tgaaatccca
     3121 tcttctgact gaagccagga cacaaaagct gatttgctct ctgcgccgaa aagggctgga
     3181 tgtaacagcg gaacgaaggg aatccgccat gaatagcgtc atgttccgca tcctcatcgt
     3241 cagcagaatc ttatctcagt ggaaagtgcc tcacataaat ccccgctgtg gtattgtcat
     3301 tctgaccctg aaaaacgatt ctggaaacag ggaataacag ttataagagc accacgattt
     3361 ccgacaggaa aacatacatg aaaatcaacg tagatgaccc tggcaaaaag agcttcgctc
     3421 tcattacgcc tcacgtgcgt taattcccga cacaccccgt gacccgtctt cgcagcctgt
     3481 accacccttt ctgccgttcc cgggattctt tctgtcacta ctcgcttgtg ccgttttttc
     3541 gcaaccggta cgtgcagtta cgacggtaca gctgcttctt ttcccgttcc gaaaggagtc
     3601 tttgatgcca cagcaacatc ccggacgact acaggtactg gtcgtcgaca cgcactgcaa
     3661 acgcaagctg ttttcaacga aaacacagac agatcccgat gagcttgccc gacgcttctg
     3721 cacgccggat aactgccttg tggtggtact atgcaacaac cgatttctgt tccgcctgga
     3781 acgtgcaccc ggtagccact gccgctggcg caagggtagc cgctcccgcc atcagcacct
     3841 gcaggactgg ctgtcgtaaa aacaacaaaa acaaaagacc tcgtcaaaac aggaggggac
     3901 catgtcgttt ttatttaaat taaccatcgc gattttgatt gtctttgcaa tcctttttcc
     3961 gattttaatt tcatcagata acaaactgtc cgcacttttt tggaagatac caaaagattt
     4021 ctgggttttc ctgattatca tgtacggggc aatcatcacg gtggtgttca tagaaagcag
     4081 tgaacaggca cgcatccgcc gccaacaata tttgcaacag tacaaaatgc caaatgagat
     4141 acatgaaaat gtggtgatag aaaacagtat tatttcaaga gaaacaacag atgacgaatc
     4201 tgacattaac accctgtacc ttgattcatt taaaagtaaa aacaactgca aatcttttga
     4261 aaccaattca aatttactgg ataaaaatgg taagcctgtg gaaataatgg tgtgtgatgt
     4321 tcaggaactg cattttttcg ttccaaagaa ttaaacagtt aatccccctt actctgttat
     4381 cttagtcgcc ggcatcaact aacatgaaaa ataataacgt accattatat ctatggttac
     4441 tttggtgtac gttttgcctg tacatcacta ccccgtggca atacttccgt tatc
//
LOCUS       DAPHKZ010000221         4405 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.224, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000221 DAPHKZ010000000
VERSION     DAPHKZ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4405
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.224"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            41..583
                     /gene="fimA"
                     /locus_tag="RH288_004501"
     CDS             41..583
                     /gene="fimA"
                     /locus_tag="RH288_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HDV4033468.1"
                     /translation="MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVN
                     TDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAIND
                     NLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
                     GTSASAGQANADATFIMRYE"
     gene            803..1495
                     /gene="fimC"
                     /locus_tag="RH288_004502"
     CDS             803..1495
                     /gene="fimC"
                     /locus_tag="RH288_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HDV4033469.1"
                     /translation="MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAKQTA
                     VWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAAD
                     RESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSR
                     SGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGNLKFQTVNDY
                     GSVTPVREVNLN"
     gene            1526..4135
                     /locus_tag="RH288_004503"
     CDS             1526..4135
                     /locus_tag="RH288_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HDV4033470.1"
                     /translation="MKIPTTTDIPQRYTWCLAGICYSSLAILPSFLSYAESYFNPAFL
                     LENGTSVADLSRFERGNHQPAGVYRVDLWRNDEFIGSQDIVFESTTENTGDKSGGLMP
                     CFNQVLLERIGLNSSAFPELAQQQNNKCINLLKAVPDATINFDFAAMRLNITIPQIAL
                     LSSAHGYIPPEEWDEGIPALLLNYNFTGNRGNGNDSYFFSELSGINIGPWRLRNNGSW
                     NYFRGNGYHSEQWNNIGTWVQRAIIPLKSELVMGDGNTGSDIFDGVGFRGVRLYSSDN
                     MYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSYVSPGAFEITDLHPTSSNGDLDV
                     TIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFRSGNSQQSSPFFFQGTALGGL
                     PQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHARSQLADDSRHEGDSIRFL
                     YAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGYEYDYDYDGEHRDEPIIVNYH
                     NLRFSRKDRLQLNISQSLNDFGSLYISGTHQKYWNTSDSDTWYQVGYTSSWVGISYSL
                     SFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASFNANRNSNGQNSW
                     LAGVGGTLLEGHNLSYHVSQGDTSNNGYTGSATANWQAAYGTLGVGYNYDRDQHDVNW
                     QLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDWRGYAVMPYATVY
                     RYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALITVTQGGKPVPF
                     GSLVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVLPKQSLQQA
                     VTVISAVCTHPSS"
     gene            4171..>4405
                     /gene="fimH"
                     /locus_tag="RH288_004504"
     CDS             4171..>4405
                     /gene="fimH"
                     /locus_tag="RH288_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415066.2"
                     /note="involved in the regulation of fimbriae length and
                     mediates adhesion of type 1 fimbriae; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrin D-mannose specific adhesin FimH"
                     /protein_id="HDV4033471.1"
                     /translation="MAMACLCLANISWATVCANSTGVAEDEHYDLSNIFNSTNNQPGQ
                     IVVLPEKSGWVGVSAICPPGTLVNYTYRSYVTNF"
BASE COUNT         1180 a          951 c         1041 g         1233 t
ORIGIN      
        1 tacggatgtg gagtcgataa atgagattga aggaatatat atgaaattaa gatttatttc
       61 gtctgcgctg gctgccgcac tattcgccgc tacgggtagt tatgctgccg ttgtagatgg
      121 cggtacaatt cactttgaag gcgaactggt gaatgctgcc tgttcagtga atactgactc
      181 ggcagaccag gttgtcacac tcggtcaata tcgtaccgat attttcaatg ctgttggtaa
      241 tacctctgca ttaattccat tcaccattca gttgaacgac tgcgatcctg ttgttgccgc
      301 taatgctgcc gttgcatttt ctggtcaggc tgatgcaatc aatgataatt tattggccat
      361 tgcatccagt accaatacaa caacagcaac gggtgtcggt attgaaatac ttgataatac
      421 atccgcaatt ctcaaacctg atgggaatag cttctcaacc aaccagaact tgatccccgg
      481 gaccaacgtt cttcattttt ctgcacgtta taaaggcacc ggtacaagtg catcagcagg
      541 gcaagcaaat gctgacgcga cttttattat gagatatgaa taatcaaaac cacgttgttt
      601 tgaattatat atcacgtctt ataacaaagt aatgtaccgg ttgtctgaag cggtatggtg
      661 gcaatgtaaa tcgaaatcat gttcactttg tatcatgccg ctttattaaa tgaaaaggga
      721 atgatgtgtt gtaagaaacc aaagcaatca tttctttata ttccttattt ttgccgtcag
      781 gaatacacaa ggcgtattaa ctatgatgac taaaataaag ttattgatgc tcattatatt
      841 ttatttaatc atttcggcca gcgcccatgc tgccggaggg atcgcattag gtgccacgcg
      901 tattatttat cccgctgatg ctaaacagac tgcggtatgg attagaaata gccataccaa
      961 tgagcgcttt ctggtcaatt cgtggattga aaacagcagc ggtgtaaaag aaaagtcatt
     1021 catcattaca ccgccactgt ttgttagtga acccaaaagc gaaaatactt tgcgtattat
     1081 ttacaccggt ccaccgctgg cagcagatcg tgagtctctg ttctggatga atgttaagac
     1141 gatcccttcg gtagataaaa atgcattgaa cggcaggaat gttttgcaac tggcgatttt
     1201 atcgcgcatg aaattatttc tccgtccaat tcaattacaa gaattacccg cagaagcgcc
     1261 ggacacactc aagttttcgc gatccggtaa ctatatcaat gttcataatc catcaccttt
     1321 ttatgtcacc ctggttaact tacaagtggg cagccaaaag ttggggaatg ctatggctgc
     1381 acccagagtt aattcacaaa ttcccttacc ctcaggagtg cagggaaatc tgaaatttca
     1441 gaccgttaat gattatggtt cagtaactcc ggtcagagaa gtgaacttaa actaaccgaa
     1501 tcatctgaca atatcagagc taattatgaa aatacccact actacggata ttccgcagag
     1561 gtatacctgg tgtctggccg gaatttgtta ttcatctctt gccattttac cctccttttt
     1621 aagctatgcg gaaagttatt tcaacccggc atttttatta gagaatggca catccgttgc
     1681 tgatttatcg cgctttgaga gaggtaatca tcaacctgcg ggcgtgtatc gggtggatct
     1741 ctggcgtaat gatgagttca ttggttcgca ggatatcgta tttgaatcga caacagaaaa
     1801 tacaggtgat aaatcaggtg ggttaatgcc ctgttttaac caggtacttc ttgaacgaat
     1861 tggccttaat agcagtgcat ttcccgagtt agcccagcag caaaacaata aatgcatcaa
     1921 tttactgaaa gctgtacctg atgccacaat taactttgat tttgcagcga tgcgcctgaa
     1981 catcactatt cctcagatag cgttgttgag tagcgctcac ggttacattc cgcctgaaga
     2041 gtgggatgaa ggtattcctg ctttactcct gaattataat ttcaccggta acagaggtaa
     2101 tggtaacgat agctattttt ttagtgagct cagcgggatt aatattggcc cgtggcgttt
     2161 acgcaacaat ggttcctgga actattttcg cggaaatgga tatcattcag aacagtggaa
     2221 taatattggc acctgggtac agcgcgccat tattccgctg aaaagtgaac tggtaatggg
     2281 agacggcaat acaggaagtg atattttcga tggcgttgga tttcgtggtg tacggcttta
     2341 ttcttctgat aatatgtatc ctgatagcca gcaagggttt gccccaacgg tacgtgggat
     2401 tgcccgtacg gcggcccagc taacgattcg gcaaaatggt tttattatct atcaaagcta
     2461 tgtttccccc ggcgcttttg aaattacaga tttgcacccg acatcttcaa atggcgatct
     2521 ggacgtcacc atcgacgagc gcgatggcaa tcagcagaat tacacaattc cgtattcaac
     2581 agtgccaatt ttacaacgcg aagggcgttt caaatttgat ctgacggcgg gcgattttcg
     2641 tagcggtaat agtcagcaat catcaccttt cttttttcag ggcacggcac tcggtggttt
     2701 accacaggaa tttactgcct acggcgggac gcaattatct gccaattaca ccgccttttt
     2761 gttagggctg gggcgcaacc tcgggaactg gggcgcagtg tcgctggatg taacgcatgc
     2821 gcgcagtcag ttagccgacg acagtcgtca tgagggggat tccattcgct tcctctatgc
     2881 gaaatcaatg aacaccttcg gcaccaattt tcagttaatg ggttaccgct attcgacaca
     2941 aggtttttat acccttgatg atgttgcgta tcgtcgaatg gaggggtacg aatatgatta
     3001 cgattacgac ggtgagcatc gcgatgaacc gataatcgtg aattaccaca atttacgctt
     3061 tagccgtaaa gaccgtttgc agttaaatat ttcacaatca cttaatgact ttggctcgct
     3121 ttatatctct ggtacccatc aaaaatactg gaatacttcg gattcagata cgtggtatca
     3181 ggtggggtat accagcagct gggttggcat cagttattcg ctctcatttt cgtggaatga
     3241 atctgtaggg atccccgata acgaacgtat tgtcggactt aatgtttcag tgcctttcaa
     3301 tgttttgacc aaacgtcgct acacccggga aaatgcgctc gaccgcgctt atgcctcctt
     3361 taacgccaac cgtaacagca acgggcaaaa tagctggctg gcaggtgtag gtgggacctt
     3421 actggaaggc cacaacctga gttatcacgt aagccagggt gatacctcga ataatgggta
     3481 cacgggcagc gccacggcaa actggcaggc cgcttacggt acgctggggg tcgggtataa
     3541 ctacgaccgc gatcaacatg acgttaactg gcagctgtct ggcggtgtgg tcgggcatga
     3601 aaatggcata acgctgagcc agcctttagg ggataccaat gttttgatta aagcgcctgg
     3661 cgcaggcggt gtacgcattg aaaatcaaac tggcatttta accgactggc gcggctatgc
     3721 ggtgatgccg tatgccacgg tttatcggta taaccgtatc gcgcttgata ccaatacgat
     3781 ggggaattcc atcgatgttg aaaaaaatat tagcagcgtt gtgccgacgc aaggcgcgtt
     3841 ggttcgtgcc aattttgata cccgcatagg cgtgcgggcg ctcattaccg ttacccaggg
     3901 cggaaaaccg gtgccgtttg gatcactggt acgggaaaac agtaccggaa taaccagtat
     3961 ggtgggtgat gacgggcaag tttatttaag tggtgcgcca ttgtctggtg aattactggt
     4021 tcagtgggga gacggcgcga actcacgctg cattgcgcac tatgtattgc cgaagcaaag
     4081 cttacagcaa gccgtcactg ttatttcggc agtttgcaca catcctagct cataaaggaa
     4141 attatcaata agataatctg cagattatta ttggcgatgg catgtttgtg tctggcaaac
     4201 atatcctggg ctactgtttg tgcaaatagt actggcgtag cagaagatga acactatgat
     4261 ctctcaaata tctttaatag caccaataac cagccagggc agattgttgt tttaccggaa
     4321 aaatccggct gggtaggtgt ctcagcaatt tgtccacccg gtacgctggt gaattataca
     4381 taccgtagtt atgtcaccaa cttta
//
LOCUS       DAPHKZ010000222         4267 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.225, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000222 DAPHKZ010000000
VERSION     DAPHKZ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4267
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.225"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..290)
                     /gene="tuf"
                     /locus_tag="RH288_004505"
     CDS             complement(<1..290)
                     /gene="tuf"
                     /locus_tag="RH288_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDV4033472.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAA"
     gene            complement(405..480)
                     /locus_tag="RH288_004506"
     tRNA            complement(405..480)
                     /locus_tag="RH288_004506"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(445..447),aa:Thr,seq:ggt)
     gene            complement(487..561)
                     /locus_tag="RH288_004507"
     tRNA            complement(487..561)
                     /locus_tag="RH288_004507"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(526..528),aa:Gly,seq:tcc)
     gene            complement(678..762)
                     /locus_tag="RH288_004508"
     tRNA            complement(678..762)
                     /locus_tag="RH288_004508"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(726..728),aa:Tyr,seq:gta)
     gene            complement(771..846)
                     /locus_tag="RH288_004509"
     tRNA            complement(771..846)
                     /locus_tag="RH288_004509"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(811..813),aa:Thr,seq:tgt)
     gene            1208..2158
                     /gene="coaA"
                     /locus_tag="RH288_004510"
                     /gene_synonym="panK"
     CDS             1208..2158
                     /gene="coaA"
                     /locus_tag="RH288_004510"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDV4033473.1"
                     /translation="MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT
                     LWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK"
     gene            complement(2187..3152)
                     /locus_tag="RH288_004511"
     CDS             complement(2187..3152)
                     /locus_tag="RH288_004511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HDV4033474.1"
                     /translation="MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELK
                     SGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
                     LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESV
                     VNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPV
                     KLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK"
     gene            complement(3149..4177)
                     /gene="murB"
                     /locus_tag="RH288_004512"
     CDS             complement(3149..4177)
                     /gene="murB"
                     /locus_tag="RH288_004512"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDV4033475.1"
                     /translation="MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVL
                     ILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMP
                     GLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRD
                     SIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKG
                     MQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGE
                     VSAVETIS"
BASE COUNT         1102 a         1053 c          960 g         1152 t
ORIGIN      
        1 gcagcaccgg tgatcatgtt tttaacatag tcggcgtgcc ccgggcagtc tacgtgtgcg
       61 tagtgacggg tcggggtgtc gtattcaacg tgagaagtgt tgatggtgat accacgagct
      121 ttttcttccg gcgcgttatc gatctggtcg aatgcgcgag cagcaccgcc gtaggtttta
      181 gccagtacgg tagtgattgc agcggtcagc gttgttttac catggtcaac gtggccgata
      241 gtaccgacgt taacgtgcgg ttttgtacgt tcaaactttt ctttagacat cgattgtccc
      301 tctaagacac ggataaatcg gtgatatcac cacatcaacc aggcaacatg cccgacttgt
      361 tgaatgcaat aaacagaagg aaaaaacagg gaggagaaaa gaagtggtgc tgataggcag
      421 attcgaactg ccgacctcac ccttaccaag ggtgcgctct accaactgag ctatatcagc
      481 acatcttgga gcgggcagcg ggaatcgaac ccgcatcatc agcttggaag gctgaggtaa
      541 tagccattat acgatgcccg catcctggaa ctcggctacc tgattttcat tctgcactga
      601 atatcgagag aagctctctt tattcgagcc ggtaagcgaa cttatcgtct cgggctacgc
      661 catcgcgtgg ccgaaattgg tggtggggga aggattcgaa ccttcgaagt ctgtgacggc
      721 agatttacag tctgctccct ttggccgctc gggaacccca ccggacttga tggtgccgac
      781 taccggaatc gaactggtga cctactgatt acaagtcagt tgctctacct actgagctaa
      841 gtcggcatca agtagcgcgc attctatgga gacatgcgag ttcatgcaac taaaaaattg
      901 cataatttgt tttattggtc acattttatg cgacacgatg aagaaacagc cgaacggagg
      961 gcagattagc acactttttc aacatcattg tgctcaacaa tgcgctcctg ctaaaccata
     1021 attcttttta tcagatggaa tatctgtcac attgcttttc aacgatagct tcctggcaga
     1081 gattttttct tattattcct ccccatctgg tgttaccctc ctgcccatta acccattcaa
     1141 cagaactgtg acgcgccatg gcaaatatcg ctttgccgat agagctatga ccgccagaaa
     1201 catgcttatg agtataaaag agcaaacgtt aatgacgcct tacctacagt ttgaccgcaa
     1261 ccagtgggca gctctgcgtg attccgtacc tatgacgtta tcggaagatg agatcgcccg
     1321 tctcaaaggt attaatgaag atctctcgtt agaagaagtt gccgagatct atttaccttt
     1381 gtcacgtttg ctgaacttct atataagctc gaatctgcgc cgtcaggcag ttctggaaca
     1441 gtttcttggt accaacgggc aacgcattcc ttacattatc agtattgctg gcagtgtcgc
     1501 ggtggggaaa agtacaaccg cccgtgtatt gcaggcgcta ttaagccgtt ggccggaaca
     1561 tcgtcgtgtt gaactgatca ctacagatgg cttccttcac cctaatcagg ttctgaaaga
     1621 acgtggtctg atgaagaaga aaggcttccc ggaatcgtat gatatgcatc gcctggtgaa
     1681 gtttgtttcc gatctcaaat ccggcgtgcc aaacgttaca gcacctgttt actcacatct
     1741 tatttatgat gtgatcccgg atggagataa aacggttgtt cagcctgata ttttaattct
     1801 tgaagggtta aatgtcttac agagcgggat ggattatcca cacgatccac atcatgtatt
     1861 tgtttctgat tttgtcgatt tttcgatata tgttgatgca ccggaagact tacttcagac
     1921 atggtatatc aaccgttttc tgaaattccg cgaaggggct tttaccgacc cggattccta
     1981 ttttcataac tacgcgaaat taactaaaga agaagcgatt aagactgcca tgacattgtg
     2041 gaaagagatc aactggctga acttaaagca aaatattcta cctactcgtg agcgcgccag
     2101 tttaatcctg acgaaaagtg ctaatcatgc ggtagaagag gtcagactac gcaaataatt
     2161 tgcaggggag cgaatactcc cctttcttat ttttctgcac tacgcaggga tatttcaccg
     2221 cccatccagg gttttattat tccatcctgc tcaagtaata aagccccctg tttgtctatt
     2281 ccgcgtgaaa tgccaaatat ttctttatca ccaatgataa gtttcactgg gcgattaata
     2341 aaattatcca gcttttccca gcgcgacaga taaggtgcca atccttcttg ttcgaagagt
     2401 tccaacgcag cacgtaattc acgtattagc atggccgcca acgtattacg atcgagattg
     2461 atccccgctt cctgcagcgt gatccacccc tgattaacga cactctcttc aacacggcgc
     2521 attgccatgt tgatcccggc tccaatgact atttgcgccg catcgccagt tttgccagtc
     2581 agctccacaa gaatgcctgc cagcttgcga tcctgcagat agaggtcatt aggccattta
     2641 acacgaactt tatctgcacc cagcttgcgt aatacttccg ccatcacgat accgataacc
     2701 agacttaaac caatcgccgc cgccgggcct tgttccagac gccagaacat cgacaaatat
     2761 aagtttgcgc caaaaggcga aaaccatttc cgaccccggc gaccacggcc agcctgctgg
     2821 tattctgcaa tgcaagcatc gcccgattta agctctccga tacgatcaag aaggtactga
     2881 ttcgtggagt caatcactgg cagcacggct acactaccgc catccagctg acccaatatc
     2941 tgtttagcat taagtaactg gataggctca ggcaggctgt atcctttacc cggaacggta
     3001 aagacatcaa cgccccagtc acgcagtgtc tgaatgtgtt tattaatagc cgcccggctc
     3061 attcccagcg tttcacccaa ctgctcgcca gagtgaaatt caccgttcgc taacagggca
     3121 atcaatttca gtggcacggt gttatccttc atgaaattgt ctccactgcg ctcacttcac
     3181 ctgatgcacc aataaagcgg acttcaggct caagccagac attaaatttt tcaccaactt
     3241 tctgtcttac atgatgcgcc agctgtacaa catcttcgct ttttgcattg tcttcattaa
     3301 tgagaactaa cgcctgttga cggtgcaccg cagccccacc tatttgcatc ccttttagct
     3361 ggcactgatc gataagccaa cctgctgcca gttttactga accatccgcc tgggggtaat
     3421 ttggtgctgt tggaaattgt gacagtaatg ctttagccgt ttcggcagat acaacagggt
     3481 ttttgaagaa actaccggca ttgccattca cttttggatc agggagtttg gtggtgcgca
     3541 tatgacacac cgcattaaat acttgctgtg gcgttactgt tgtaggatcc agacgagtta
     3601 agtcaccata cgttagtaca ggttgccact cttttggcag acgcagacct acggctacaa
     3661 tagcgaagcg gtcctggtat tcatgtttaa aaatactgtc gcgatagcca aaacggcact
     3721 ctttggcagt taagcgcact tgcttgcctg tcgccagttc aacagaatca acataagcgc
     3781 aaactcgctg taattctacg ccataagcac caatattctg gataggtgat gagccgacac
     3841 aaccaggaat taatgccaga ttttccagac caggcatacc ttcctgcaaa gtgtatttta
     3901 ccagacgatg ccagttttct ccggctccta catgtaaata ccacgcatca ggttcatcat
     3961 gaatttcgat acctttgatc cggttgatga tcaccgtgcc gcgatagtcc tccagaaaaa
     4021 gtacattact tccttcaccc agaataagaa cgggttgtcc ttctgcggtt gcatactgcc
     4081 aggcattgag taattgttgt tcgtcttcgg cacatacaat gtgctgagca ttatgatcaa
     4141 tgccaaatgt gttccagggt tttaaggagt ggttcatagc tgctttcctg atgcaaaaac
     4201 gaggctagtt taccgtatct gtggggggat ggcttgtaga tatgacgaca ggaagagttt
     4261 gtagaaa
//
LOCUS       DAPHKZ010000223         4073 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.226, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000223 DAPHKZ010000000
VERSION     DAPHKZ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4073
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.226"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..591
                     /locus_tag="RH288_004513"
     CDS             <1..591
                     /locus_tag="RH288_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001448734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033476.1"
                     /translation="KKNPSMANTKIIAPHDDIIAHTDFYTWQAVLSDAFHTQSRSEAS
                     RALWPRLTYRVLKGLDRSKDEGTARIDFLNELNEIRNYRNRLSHNDCIWIKIHSKNLQ
                     SAVETIREKINKIEGLIKTINPQVHLSLTKWGSFYHAKRICSQKEAELHLGKGIINST
                     TDEMNTILDQLYALTADGKLTGVVKRNTNNIAFHKF"
     gene            1185..1778
                     /locus_tag="RH288_004514"
     CDS             1185..1778
                     /locus_tag="RH288_004514"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDV4033477.1"
                     /translation="MSGRKFGRLPNWWARSSWLVNNVRSNEIGGGIASMKCLLALSVL
                     IDFHSRTASVSFTGMERLTGLSRPMIVKGVAKLEKDGLIKIDREMFVNSYELTVQPND
                     DRWAKVPVDTIRKKLNTISNRGMAPFVALKLYLTIISLRYQSNNTVKVTHETLRSYTG
                     VQPNQIRFGLDVLYCSRLIHLQPKEDRESNIYEIIGL"
     gene            2551..2745
                     /locus_tag="RH288_004515"
     CDS             2551..2745
                     /locus_tag="RH288_004515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="HDV4033478.1"
                     /translation="MNKQQQTALNMARFIKSQSLTLLEKLDALDADEQAAMCERLHEL
                     AEELQNSIQVRFETESETGT"
BASE COUNT         1331 a          925 c          871 g          946 t
ORIGIN      
        1 aaaaaaaacc catcaatggc aaataccaaa ataattgcac ctcatgatga catcattgca
       61 cacacagatt tttacacatg gcaagcggtt ttgagcgatg cttttcatac acaatcaaga
      121 tctgaagcat caagagcctt atggcccagg ctcacctaca gagtactgaa gggattagat
      181 agaagcaaag atgaaggcac agccagaatt gatttcttaa acgagctgaa tgagatcaga
      241 aactacagaa ataggttatc gcataatgat tgcatatgga taaaaataca ctctaaaaat
      301 ttgcaatctg cagtagaaac aataagagaa aaaataaaca aaatagaagg actgataaaa
      361 acgataaacc cacaggtaca cctatcatta acgaagtggg gttcctttta tcacgccaaa
      421 agaatatgtt ctcaaaaaga ggccgaattg catctaggca aaggaataat caatagcaca
      481 acagatgaga tgaacacaat tctagatcaa ctatacgcac taactgctga cggaaagcta
      541 acgggtgttg taaaacgaaa taccaacaat atcgcatttc acaagtttta gatcacaaaa
      601 tagaaaaggc ccgacagttt cctgtcgagc ctcatccaaa tctcttgcca ttatcacctt
      661 tcggtggagc gtggccttaa tgtcattgtg aatctataaa aatttcacaa tgcattaaag
      721 cgaaagctca aggcttcact gccatacatg atacatcatc atcaggaaaa agagcaaact
      781 atttcccatg atcacgccaa agcttaccat ccaccattta ccaatagatc aaaaaataca
      841 caacaaaaat aactaaaaac gccgattaaa ccagcattat caaatttaca tttaccagtt
      901 aaaaaacgat aaaaacaaga taacatcatg ttttatatgg gaaaacaagc agccaccaaa
      961 tattgcttta tctagattta ttctaataag cgtatataaa gttaaaacac aacaacttag
     1021 tatgcgactg gaggaccaat tggaaaccct caacaatttg ctggtaacgc taacttccgc
     1081 aaagccggag gttttggttt ctgttgtatc tttaggtgca atggttttca tgtatatgat
     1141 aataaagcta tttatatctc tccttgaccg aaaatggggt aaaaatgagc ggtagaaaat
     1201 ttggcaggct tccaaactgg tgggcccgaa gctcatggct tgtaaacaat gttcgttcaa
     1261 atgagatagg gggcggcatt gcatcaatga aatgcttgtt agctctatcc gtcttgattg
     1321 atttccattc aagaacagcc tcagtatcat ttaccggaat ggaaagactg actggactaa
     1381 gccgccccat gatagtgaaa ggagtagcca aacttgagaa agatggtctt ataaagatag
     1441 atagagagat gtttgttaac tcctatgaat taacagtaca gccaaatgat gataggtggg
     1501 caaaagtacc agtagatact atcaggaaaa aactaaacac catatcgaac agggggatgg
     1561 ccccatttgt ggcattaaaa ctatatttaa caattataag ccttcgttat cagtcaaata
     1621 atactgttaa ggtgacacat gaaacactga gaagctatac aggtgtccag ccaaaccaga
     1681 ttaggttcgg cttagatgta ctgtactgta gtcgcctgat acatctgcaa ccaaaagaag
     1741 atagagagtc aaacatctat gaaataatcg gcctatgagg aaatgcattt accataacgt
     1801 cgcattacgc gcaccgctaa aacgcactga acgcgattct gacgcagata ccgcaaaaag
     1861 agatgtttta cccagtgaaa accgaaaaaa tgcgtcagga tcgttttcag cccactgcat
     1921 agctatgcat gaaaatgaat gacgaacggt ttgggcgcat acggtgccca tgagacacat
     1981 tttcggacat tttcagttcg tgaatccctg actcattgct acatatctga acagacaccc
     2041 ctggcagcgc ccccaggggc gtcctgtaaa aaaacacacc gcgccgctag cagcacccct
     2101 gatataaaat gatgtttttt ataaaaatag tcagtaccac ccctacaaag cggtgtcggc
     2161 gcggtgttgt agctgcgccg gcaccgcttt tttaaatatc gcaaagagag caagagaaac
     2221 taatttttca taactctcta tttataaaga aaaatcagca aaaacttgtt tttgcgtggg
     2281 gtgtgggcat ttcaggaatg agaacagact cgcgtttttc cggagtatca gcggaattat
     2341 tgattaagaa acactcgacg cagagcgaaa ttttatgcaa cagcggctgc actgcacagg
     2401 gattatttat cagttgatat gctgtgccat gatacgtcct aaaaaaatag gacaggatgt
     2461 gcaattgtaa taccgtcgcc cgcaacgtct tacaattacc agctgctcag ggtccccccg
     2521 acacccggaa ctgacggaga acaacggaag gtgaacaaac aacaacaaac tgcgctgaat
     2581 atggcgcgat ttatcaaaag ccagagcctg acactgcttg aaaaactgga tgctctggat
     2641 gccgacgaac aggcagccat gtgcgaacga ctgcacgaac tcgcggaaga actccagaac
     2701 agcatccagg ttcgctttga gaccgaaagt gaaacaggaa cataacgaag ctgacggagg
     2761 cgctcacggc ttgtccgcga gcgttttcgg cagcagacaa gcccgtcagg gcgcgtcagg
     2821 gggttttagc gggtgtcggg gcgcagccat gacccagtca cgtagcgata gcggagtgta
     2881 tactggctta accatgcggc atcagtgcgg attgtatgaa aagtgcccca tgccgggtgt
     2941 gaaatgccgc acagatgcgt aaggagaaaa tgcacgtcca ggcgcttttc cgcttcctcg
     3001 ctcactgact cgctacgctc ggtcgttcgg ctgcggcgag cggtactgac tcacacaaaa
     3061 acggtaacac agttatccac agaatcaggg gataagaccg gaaagaacat gtgagcaaca
     3121 aggcaaagcc aggacaaaag gccgcgccgc tggcgttttt ccataggctc cgcccccctg
     3181 acgagcatca aaaaaaccga cgctcaagtc agaggtggcg aaacccgaca ggactataaa
     3241 gataccaggc gtttccccct ggaagctccc tcgtgcgctc tcctgttccg accctgccgc
     3301 ttaccggata cctgtccgcc tttctccctt cgggaagcgt ggcgctttct catagctcac
     3361 gctgttggta tctcagttcg gtgtaggtcg ttcgctccaa gctgggctgt gtgcacgaac
     3421 cccccgttca gcccgaccgc tgcgccttat ccggtaacta tcgtcttgag tccaacccgg
     3481 taaggcacgc cttaacgcca ctggcagcag ccactggtaa ctgatttaga ggagtttgtc
     3541 ttgaagttat gcacctgtta aggctaaact gaaagaacag attttggtga ctgcgctcct
     3601 ccaagccagt taccttggtt cacagagcgc caactctttg aaccttcgaa aaaccgcccg
     3661 ccaaggcggt tttttcgttt aacactctac aactatccat acgtgtatgg caacatccaa
     3721 tcaccactaa gtgtatgata gagatggata tgccaaatac aattcattac cctcatgtaa
     3781 taccatttat atcccaagga aaaataaatg ctataaaaag cacgtttggt aataacctgt
     3841 ctgataggga gtgctacggg atatatatat ggagccagaa agcctcatct gccatatatc
     3901 cattactgca acaactcgaa gttactttga gaaactcgat tgataaagaa gcgacaaaac
     3961 taataggcca aaaatggtgg gataatgtat acaccgacac atcaaaaagc aaacacggtg
     4021 acttcataca taatataaac aaagcaaaaa gaagatatga gaatgaattc aag
//
LOCUS       DAPHKZ010000224         4060 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.227, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000224 DAPHKZ010000000
VERSION     DAPHKZ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4060
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.227"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            144..752
                     /locus_tag="RH288_004516"
     CDS             144..752
                     /locus_tag="RH288_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HDV4033479.1"
                     /translation="MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFN
                     PLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMD
                     AGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA"
     gene            850..2241
                     /gene="selA"
                     /locus_tag="RH288_004517"
     CDS             850..2241
                     /gene="selA"
                     /locus_tag="RH288_004517"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDV4033480.1"
                     /translation="MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQML
                     DEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAE
                     AAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNEN
                     TALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEP
                     MPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLS
                     QIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRC
                     LEDEQRFLEMLLK"
     gene            2238..>4060
                     /gene="selB"
                     /locus_tag="RH288_004518"
     CDS             2238..>4060
                     /gene="selB"
                     /locus_tag="RH288_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDV4033481.1"
                     /translation="MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLT
                     GNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGMDALREH
                     LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRV
                     RALHAQNQPTETANAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHT
                     PLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRLVLRDISARNTLAG
                     ARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGE
                     GMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMAL
                     PMEDEALVLLLIEKMRESGDILSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWW
                     VRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGS
                     TCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDA"
BASE COUNT          910 a         1037 c         1200 g          913 t
ORIGIN      
        1 atcagataga aacaattagg aaaatattta tatcaccatg ataaatatgt gatttatttg
       61 gaagtaacaa accatcaaca ttttctgccc tttttcccat caccaggcca tactgatatt
      121 tttcctcgca caaaggactc ggcatgaaac tcgtcggtag ctacaccagc ccgtttgtac
      181 gcaaactttc tattctgttg ttagaaaagg gcataacttt cgaatttatt aatgaactgc
      241 cctataacgc ggacaacggc gtggcgcaat ttaacccgtt aggaaaagtg ccggtgctgg
      301 tgaccgaaga gggcgaatgt tggtttgatt cgccgatcat cgctgaatat attgaattaa
      361 tgaatgtcgc tccggcgatg ttgccgcgcg atccgctgga gtcgttgcgg gtgcgcaaaa
      421 ttgaggcact ggcggatggc attatggatg ccgggctggt atcggtgcgt gaacaggcgc
      481 gtccagcggc gcagcagtct gaagatgaat tgttacgcca gcgggagaaa atcaaccgca
      541 gtctggatgt gctggaagga tatctggtcg atggcacact caaaaccgat acggtcaatc
      601 tggcgactat cgccattgcc tgtgccgtcg gatatctcaa tttccgccgc gttgcgccag
      661 gttggtgtgt cgaccgccca cacttagtca aactggtcga aaacctgttt agccgcgaaa
      721 gttttgctcg caccgaaccg ccaaaggctt gatgcgcgat atgtcctcct gacccatctc
      781 acgttacaat ccgtggttat gttaaacgcc cttctccgtg tgagagggcc ttgatcagcc
      841 aggtttccta tgacaaccga aacgcgttcc ctctatagtc aacttccggc tattgatcgc
      901 ttattgcgcg atagctcctt cctttctttg cgtgatactt atggtcacac ccgcgtggtg
      961 gaattgttgc gtcagatgct cgacgaagcg cgagaagtga ttcgtggcag ccagacgctg
     1021 cctgcgtggt gtgaaaactg ggcgcaagaa gtcgatgccc ggttgacgaa agaagcgcag
     1081 agcgcgctgc gtccggtgat caacctgacg ggaaccgtgc tgcataccaa ccttgggcga
     1141 gctttacagg cggaagccgc ggtggaagcc gttgcgcagg ctatgcgttc gccagtgacc
     1201 ctcgagtatg atctggacga cgccggacgc ggacatcgcg atcgggcgct ggcgcagctg
     1261 ctgtgccgta ttacgggggc ggaagatgcc tgtatcgtca ataacaatgc ggcggcggtg
     1321 ttattgatgt tggcggccac tgccagcgga aaagaggtgg tggtatctcg cggcgaactg
     1381 gtggagattg gcggcgcgtt tcgtattccc gatgttatgc gtcaggcagg ctgcacccta
     1441 cacgaagtag ggaccaccaa ccgcacgcac gcgaatgatt atcgtcaggc ggtgaatgaa
     1501 aataccgcac tgttgatgaa agtacatacc agtaactaca gcattcaggg gttcaccaaa
     1561 gcgatagatg aagcggaact ggtggcgctc ggcaaagagc tggatgttcc cgtagtgact
     1621 gatttaggca gtggctcgct ggtcgatctt agccagtacg gtttgccgaa agagccaatg
     1681 ccgcaggagt tgattgcggc gggcgtcagt ctggtgagtt tctccggcga caagttgtta
     1741 ggcgggccgc aggcaggaat tattgttggt aaaaaagaga tgatcgcccg cctgcaaagc
     1801 cacccgctga agcgtgcatt acgcgcggat aaaatgaccc tcgcggcgct ggaagccacg
     1861 ttgcgtcttt atttacaccc tgaagctctg agtgaaaaat taccgaccct gcgcctgctt
     1921 acccgcagcg cagaggtcat tcaaatccag gcacaacgtt tacaggcccc ccttgccgca
     1981 cattacggcg cggagtttgc ggtacaggtt atgccatgtc tttcgcagat tggcagtggt
     2041 tcgctgccgg ttgatcgcct gccgagcgcg gcattaacgt ttacacccca tgatggacgc
     2101 ggtagccacc ttgagtcatt agccgcccgc tggcgtgaat tgccagtgcc ggtgattggt
     2161 cgtatttatg acggacgatt gtggctggat ttacgctgcc ttgaagatga gcaacggttt
     2221 ttggagatgt tgttgaaatg attattgcga ctgccggaca cgttgaccac ggcaaaacaa
     2281 ccttattgca ggcgattact ggcgtaaatg ctgaccgtct gccggaagaa aaaaagcgcg
     2341 gcatgaccat cgatctcggc tatgcctact ggccgcagcc ggatggtcgc gtgcctggtt
     2401 ttatcgacgt tcccggtcat gaaaagtttc tttccaacat gctggcgggc gttggtggta
     2461 tcgatcacgc gctgttggtg gtggcgtgcg atgacggcgt gatggcacag acccgtgagc
     2521 atctggcgat tttgcagctg accggtaacc cgatgctgac agtggcgctg accaaagccg
     2581 atcgcgtgga cgaagcgcgt gttgatgagg ttgaacgcca ggtaaaggag gttctgcggg
     2641 aatacggttt tgctgaggca aaactgttta tcaccgcagc aaccgaaggt cggggaatgg
     2701 atgccctgcg cgagcatctg cttcagttgc cggaacgcga gcacgccagc caacatagtt
     2761 tccgcctcgc gattgaccgc gcatttaccg taaaaggtgc cgggctggtc gtcaccggta
     2821 cggcgttaag cggggaagtg aaggtaggcg attcactctg gctgactggt gtaaataaac
     2881 cgatgcgtgt acgtgcgctg catgcgcaaa accagccaac agaaaccgcc aatgccgggc
     2941 agcgtatcgc gcttaacatc gcgggtgatg cggaaaaaga gcagattaac cgtggcgact
     3001 ggctgcttgc cgatgtgccg ccagagccgt tcacacgggt gattgtcgag cttcaaaccc
     3061 atacaccgct gacccagtgg cagccgctgc atattcacca cgccgccagc cacgtcacgg
     3121 gacgcgtttc actgctggaa gataaccttg ctgaactggt cttcgacacc ccgttatggc
     3181 tggcagataa cgaccgcctg gtattgcgcg atatctctgc ccgcaacacg ctggccggag
     3241 cgcgcgtcgt gatgcttaac ccgccgcgtc gcggtaaacg taagccggaa tatctgcaat
     3301 ggctggcgtc tcttgcacgg gcgcagagcg atgccgatgc gttatctgtt catctggaac
     3361 gcggcgcggt taaccttgcg gatttcgcct gggcgcgcca gctcaacggc gaagggatgc
     3421 gcgaattgct gcaacagcct ggttatattc aggctggtta tagcttgttg aatgcgccgg
     3481 ttgccgcccg ctggcagcgg aaaattctcg acacattagc gacttatcat gagcaacatc
     3541 gcgatgaacc tggtcctggg cgcgaacgtc tgcgacgtat ggcgttgcca atggaagatg
     3601 aagcgctggt actgttgctg attgaaaaga tgcgcgaaag cggcgacatc ctcagtcatc
     3661 acggttggct gcatctgcca gatcacaaag cgggcttcag cgaagagcag caggccatct
     3721 ggcaaaaagc agagccgctg tttggtgacg agccgtggtg ggtgcgtgac ctggcaaaag
     3781 agacgggaac cgacgagcag gcaatgcgcc tgacgctgcg ccaggcggcg cagcaaggaa
     3841 taattaccgc gatcgtcaaa gatcgttatt accgtaacga tcggattgtc gaatttgcca
     3901 atatgatccg cgatctcgat caggagtgtg gttcaacctg cgcggcggat ttccgcgatc
     3961 gcttaggcgt aggccgaaag ctggcaattc agattctgga atattttgac cgcattggct
     4021 ttacgcgtcg tcgtggaaat gatcatttat tgcgcgacgc
//
LOCUS       DAPHKZ010000225         4041 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.228, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000225 DAPHKZ010000000
VERSION     DAPHKZ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4041
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.228"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            51..1709
                     /gene="dpiB"
                     /locus_tag="RH288_004519"
     CDS             51..1709
                     /gene="dpiB"
                     /locus_tag="RH288_004519"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HDV4033482.1"
                     /translation="MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTAS
                     FEDYLTLHVRDMAMNQAKIIASNDSVISAVKTRDYKRLATIANKLQRDTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKQGALEKGESYFITGKGSMGMAMRAKTPIFDDDGKVI
                     GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIVEVVRPA
                     DFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFAD
                     RQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLR
                     SDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLY
                     LIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR"
     gene            1678..2358
                     /gene="dpiA"
                     /locus_tag="RH288_004520"
                     /gene_synonym="citB"
     CDS             1678..2358
                     /gene="dpiA"
                     /locus_tag="RH288_004520"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HDV4033483.1"
                     /translation="MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARM
                     MIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVF
                     DYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
                     PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGR
                     PQRIYHSG"
     gene            complement(2399..3784)
                     /gene="dcuC"
                     /locus_tag="RH288_004521"
     CDS             complement(2399..3784)
                     /gene="dcuC"
                     /locus_tag="RH288_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HDV4033484.1"
                     /translation="MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAI
                     MGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLIASILEFLRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELM
                     VPGTAAAVTGK"
BASE COUNT         1105 a          950 c         1045 g          941 t
ORIGIN      
        1 attttaatta catccgtcaa agaggctcgg gacaacccgc aaggaaaaca atgttgcagc
       61 ttaacgagaa taaacagttt gcatttttcc aaagactggc atttccgctg cgtatctttt
      121 tgctgattct ggtgttctca atatttgtca ttgcagccct ggcgcaatat tttacggcca
      181 gttttgagga ctatttaacg cttcatgtac gcgacatggc aatgaatcag gcgaaaatta
      241 ttgcctccaa tgacagtgtc atctctgcgg tgaaaacgcg tgactacaaa cggctggcga
      301 ccatcgctaa caaattacaa agagataccg attttgatta tgtggtgatt ggggaccggc
      361 actcgatccg cctttaccat cctaatccgg agaaaattgg ttatcctatg cagttcacca
      421 aacagggcgc gctggagaaa ggggagagct acttcattac cgggaaaggg tcaatgggga
      481 tggcgatgcg cgccaaaacg ccaatctttg atgacgatgg aaaagtcatc ggcgtggtgt
      541 cgattggcta cctggtgagt aaaatcgata gctggcgggc tgagttttta ttaccgatgg
      601 caggtgtgtt tgtcgtgctg ttagggattc tgatgttgct gtcgtggttc ctggccgcgc
      661 atatccgtcg gcagatgatg ggcatggagc caaagcaaat cgcacgcgtg gtccgtcagc
      721 aagaggcgct gtttagttcg gtttatgaag ggctgattgc ggtggatccg catggttaca
      781 ttaccgccat caatcgtaac gcaagaaaga tgctggggct gagttccccc ggacggcaat
      841 ggttgggtaa acccattgtt gaagtggtca ggcccgccga tttctttacc gaacagattg
      901 atgaaaaacg tcaggatgtg gtggcgaact ttaacggtct gagcgttatt gccaaccggg
      961 aagctattcg ttcaggtgat gatttgctgg gggccattat cagctttcgt agtaaagacg
     1021 aaatttccac cctcaatgcg caactgacgc aaataaaaca atacgttgag agccttcgta
     1081 cattgcgaca cgagcatctc aattggatgt cgacgctcaa tggtctgttg cagatgaaag
     1141 agtatgatcg cgtgctggcg atggtgcagg gggagtctca ggcccagcaa cagcttattg
     1201 acagcctgcg cgaggcgttt gccgatcgcc aggtggcggg gctgcttttt ggtaaagtgc
     1261 agcgcgcccg ggaactgggg ctaaaaatga tcattgtccc cggtagccag ctttcgcaac
     1321 tgccgccagg actggatagc accgagtttg cagccattgt gggcaattta cttgataacg
     1381 ccttcgaagc cagcctgcgt agcgatgaag gaaacaagat cgttgaatta ttcctcagcg
     1441 atgaaggcga tgatgtggtg attgaagtcg ccgatcaggg ctgcggcgtt ccagagtctc
     1501 tacgagacaa aatatttgag cagggggtca gtacgcgtgc tgacgagccc ggtgaacatg
     1561 gcattgggtt gtacttgatt gccagctacg taacgcgctg cggtggtgtt atcactctcg
     1621 aagataatga tccctgcggt accttatttt caatctatat tccgaaagtg aaacctaatg
     1681 acagctccat taaccctatt gatcgttgag gacgaaacgc cgctggcaga gatgcatgcg
     1741 gaatatattc gtcacattcc cggattcagt cagatattac tggcgggaaa tctggcgcag
     1801 gcccgaatga tgatcgagcg ttttaagccg gggctaatct tgctcgataa ctatcttcct
     1861 gacggtagag ggattaattt actgcatgaa ctggtgcagg cgcattatcc cggcgacgtg
     1921 gtgtttacca ctgcagccag cgatatggaa acggtgtctg aagccgtacg ttgtggtgta
     1981 tttgattatc tcattaagcc cattgcctat gaacggctgg ggcaaacgct aacccgtttc
     2041 cgccagcgta aacatatgct ggaaagtatt gatagcgcca gccagaagca aattgatgag
     2101 atgtttaatg cttatgctcg cggtgaacct aaggacgagc taccgaccgg cattgacccc
     2161 ttgacgctaa acgcggtgcg aaaactgttt aaagagcctg gtgtgcaaca tacggcagaa
     2221 acggtggcgc aggcactgac catcagccgc accactgcca ggcgttatct tgaatattgc
     2281 gccagccgcc atctgattat tgctgaaatt gttcacggca aagttggcag accacaacgc
     2341 atataccaca gtgggtgaca tgataaagcc ggaggaaact tgcctccggc attactattt
     2401 acttgcctgt gaccgctgct gccgttcctg gcaccatcag ctctgtagca acgataacaa
     2461 tcaccaaacc aacaagcacc ggtaccgagg tgcgttttac gacttcaaac ggcgagatct
     2521 tcgccatccc ggcaaccgca acgactacgc cagaaacggg cgaaagggta cggccaaggt
     2581 ttgacgcctg cagcatcggg atagtcaaat acgccgggtt aatgccggaa gagtgcgcca
     2641 gtttcgggat catctcaaca aacgcataaa acggcgcatt gcctgaaccg gtcgtgactg
     2701 ccgccagcat tgtcagaatc accaatacca gcatcaggat gatactcgcc gaaccaaacg
     2761 aggtagcgat agaaatcaga ctttgaataa agccgatggt gctaagcccc tgagcgaata
     2821 ccccagcggc aaccagcagc atcaccacgt tagcaaacgc atctgccatc ccgcgataag
     2881 ccacttccag accagagaaa actttctggg tattaaagct gcggaggaac tccagaatgg
     2941 aggcaatcag catacaaatc accagaatag tgatgatgtg taattgcgga ccccatttac
     3001 cgtcaaaaat cagtacaccg atgatcggcg tgaacggcaa aatggcataa aacgcaggag
     3061 cagtggtggt gatttcactg acatctaaca tttcatgaga gatgtgctct tttttatcca
     3121 gataacgttg ccagaagaag tgggcgatcg ccatgccgat aattgcagca attgagatag
     3181 gcagcgtcgt tttgaaggcg aagtcaatca gcgacatttc ggaagcttgc gccgccagca
     3241 ccacatcccc tgaagtcggt gcgagaataa tcgccgccgg ggaggcacaa atggcagcag
     3301 ctgcgccacg actgatacca acgtttacca tcaccggaaa tagggttgcc atcagcaaaa
     3361 cacccagacc ggttgcggaa gagacggcca gagacatcag acaggcgaca aaataggcgg
     3421 caatcatcag caggtaaggg gagttaatat actgcaatgg ttttgacgcc agcttgacca
     3481 ccatatcatt cgcgccgata tgggtcatgt aagcggcaaa tccacacagc atcataatca
     3541 tcatgccgag gtcgccgccg cggctcatta gtaatatttt aacgtattca acgatatccg
     3601 tggcgctgta gcctgttgaa gcctggctgg acggtaacac tttgtgcccc ataatggcac
     3661 tgataatcag caataacagg ccaccgacaa ataacacacc agtggcggaa taccctttaa
     3721 tgatgtagcg agctacaccc acaataacca caaccccaat aaggagctca atgaatgtca
     3781 gcataatttt tcctgtctcc aggccccaaa gtaaataata aaaaattcct aaagcttaag
     3841 gaaaaaatat gcccaataaa ttggcgatga atgctgatta aaatcaagaa aaactgccat
     3901 taagacattg aagttgctgt ttttatacat agataacaaa acgcatattt agcggttggc
     3961 aattatcaca taataatgtg tgcaaattga tggtggattg atgcaaattt gttaattgca
     4021 atggtgttag ctgcggctgt g
//
LOCUS       DAPHKZ010000226         3989 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.229, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000226 DAPHKZ010000000
VERSION     DAPHKZ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3989
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.229"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            148..3894
                     /locus_tag="RH288_004522"
                     /pseudo
     CDS             148..3894
                     /locus_tag="RH288_004522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
BASE COUNT          979 a         1084 c         1235 g          691 t
ORIGIN      
        1 aaatcctgtc aattaattct tcccgttgat atcagtcaaa aaaataaatg taaaaaagcg
       61 tatttcgttt catacagtaa cgttatttat cattttgtcc ggtgccgcca gcatcaggcc
      121 agatgaacca taaaaaggat atcagcgatg agcggaaaac cagcggcacg tcagggagac
      181 atgacccagt acggcggccc gatagtccag gggtcggcag gcgtgagaat tggcgcgcca
      241 accggcgtgg cctgttcagt atgtcccggc ggagtcactt ccggcaaccc ggtgaatccg
      301 ctgctcggtg caaaggtgct gcccggcgaa accgatttcg cgctacccgg cccgttaccg
      361 ttcattcttt cccgcaccta cagcagctac cggacgaaaa cccctgcgcc cgtcggtatc
      421 ttcggtcccg gctggaaagc gccctctgat atccacttac agttacgcga taacgaactg
      481 atactcaatg ataacggtgg cagaagcatt cattttgagc acctgtttcc cggtgaggat
      541 ggcttcagcc gcagcgaatt attctggctg gtgcgcggcg gcgtggcgaa actgaatgaa
      601 agtcaccgtc ttgccccact ctggcaggct ctgccggaag aactccgcct gagtccgcat
      661 atttatctgg cgacgaacag tccgcagggg ccgtggtgga tactcggctg gagtgagcgg
      721 gtaccgggtg tggatgagat gctgcctgct ccgctgccgc cgtaccgggt actgaccggc
      781 ctggtggacc gcttcgggcg cacactgacc ttccggcgtg aggccgcagg cgaatttacc
      841 ggggaaatca ccggcgtgac cgatggcgcc ggccgtcagt tccgtctggt gctgaccacg
      901 caggcacaac gggcagaaaa cgcccggcag caggccatcg ccgcaggaac gaaaggatcg
      961 gatatcccgg attcactgcc ggactatacg gagtatggcc gggataacgg tatccgcctg
     1021 tcaggggtgt ggctgacgca cgacccggaa tacccggaga atctgcccgc cgcccccctg
     1081 gtacgctacg actggacggc acgcggtgag ctggcggcgg tgtatgaccg cagcggtact
     1141 cagatgcgcc actttactta cgatgataaa taccggggcc ggatggtggc gcaccgttac
     1201 gcaggcaggc cggagatgcg ttaccgctac gacgacatag gtcgcgtgac ggagcagttt
     1261 aatccggcag gcttaagcta cgcctatcag tatgagaaaa accgtatcac catcaccgac
     1321 agcctgaacc ggcgggaggt gctgcacacg gaaggtgaag ccgggctgaa acgtgtggtg
     1381 aaaaaggaat tcgcggatgg cagcatcacc cgaagtaaat ttgactatat ggggcgactc
     1441 cagtcacaga cggatgcagc aggccggaca acagaataca gtccgaatgt ggtgacggga
     1501 ctcgtcacgt gcatcaccac gccggacggc aggaaatcgg aattttacta taacaatcaa
     1561 aaccagttaa cctcagccac cgggcctgac ggactggaaa tgcgccggaa atatgatgag
     1621 tacgggcgtc tgacgcagga aacagcacgc aacggcgatg tcacccgcta cagttatgat
     1681 aatccacaca gtgaattacc ctctgtaaca gaagatgcga cgggtagccg caagcagatg
     1741 acgtggagcc gctacgggca gttacagacc ttcaccgact gctcaggcta tgaaacccgt
     1801 tatgaatatg accgcttcgg gcaaatgacg gcggttcacc gtgaggaaag catcagcctt
     1861 taccgcagtt acgacaaccg tggccagtta atctcggtga aagatacgca gggccgtgaa
     1921 acgcagtatg aatacaacgc cgcaggcgac ctgaccgccg tcatcacccc ggacggcaac
     1981 cggagtgaga cactgtacga tgcgtgggga aaggccgtca gcaccacaca gggtggtctg
     2041 acgcgcagca tggaatacga tgcagcggga cgtgtcatca gcctgaccaa cgagaacggt
     2101 agccatacag aatttagctg ggatgtgctt gaccgcctga tacagcagcg cggctttgac
     2161 gggcggacgc agcgttaccg ttatgacctg accgggaaac tcacgcagag cgaggatgag
     2221 gggcttatca ccctctggca ctacgatgca tcggaccgta tcacacaccg cacggtgaac
     2281 ggcgaaccgg cagagcagtg gcggtataac gaccacggct ggctgacaga aatcagccat
     2341 ctcagcgaag gccaccgggt ggcggtgcat tacggttata accgtaaggg acgtctcaca
     2401 ggcgagcgcc agacggtaca tcacccggag acgggggaac tgctctggca gcatgagacg
     2461 aaacacactt acaacgagca ggggctggca aaccgctttc aggcagacag cctgccaccg
     2521 gtggagtggc taacgtatgg cagcggttac ctggcgggaa tgaaactggg cgacacgccg
     2581 ctggtggagt acacacggga cagactgcac cgggaaacgg tgcgcagctt cggcaataat
     2641 gcatatgaac tgaccagcac atacactcac gcaggccggt tacagaatca gcacctgaac
     2701 agcctggtgt atgaccgtga ctatggctgg aatgacaatg gcgacctggt gcgcatcagc
     2761 ggcccgcggc agacgcggga atacggctac agtgccacgg gcaggctgga gagtgtgcgc
     2821 accctcgcac cggacctgga tatccgcatc ccgtatgcct ccgacccggc gggaaaccgc
     2881 ctgccggacc cggagctgca cccggacagt acactcacgg cgtggccgga taaccgaatc
     2941 accgaagacg cgcactacct gtaccgctat gacaggtatg gcaggctgac ggagaagacg
     3001 gaccgcatcc cgacgggtgt gatacggacg gacgacgagc ggacccacca ctaccactac
     3061 gacagccagc accggctggt gttttatacg cggatacagc atgaggagcc actggtcgag
     3121 agccgctatc tctacgaccc gctgggccgc cggacgggga aacgggtgtg gcgtcgcgag
     3181 cgtgatctga caggatggat gtcgctgtcg cgtaaaccgg aggtgacgtg gtacggatgg
     3241 gacggcgacc ggctgacgac ggtacagacc gacaccacgc gtatccagac ggtatatcag
     3301 ccggggagct tcgcgccgct catccgcatc gagacagaga acggcgaact ggataaagcg
     3361 cagcggcgca gcctggtgga gaagttacag caggaaggga gtgaggacgg tcacggtgtg
     3421 gtgttcccgg tggaactggt gaggatgctg gacaggctgg agggggaaat ccgggcagac
     3481 cgcgtgagca gtgagagccg ggcgtggctg gcgcagtgcg ggctgacggt ggagcggctg
     3541 gcggcacaga tagagccggt ttatttacct gagcgaaaag ttcaccttta tcactgcgac
     3601 caccggggac tgccgctggc gctcatcagc gaagacggca atacgatgtg gagcgcggag
     3661 tatgatgagt ggggaaacct gttgaatgag gagaacccgc atcacctgta ccagccgtac
     3721 cgcctgccgg ggcagcagta cgatgatgaa tcggggctgt gctataaccg taaccggtac
     3781 tacgatccgt tgcagggacg gtatatcacc caggatccga ttgggctgag tggtgggctg
     3841 aatacatatt cgtatccatt aaatccaata aatgaaatag atcctttagg attaaaagtg
     3901 atcgttgtag ctagtgatcc taatgaggca aaattattac aggaggcata tgcacaatta
     3961 aatacaacaa agagaggaca agaaataac
//
LOCUS       DAPHKZ010000227         3939 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.230, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000227 DAPHKZ010000000
VERSION     DAPHKZ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3939
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.230"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            359..1261
                     /locus_tag="RH288_004523"
     CDS             359..1261
                     /locus_tag="RH288_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HDV4033485.1"
                     /translation="MYFSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLL
                     QITENIRSEQCPGVTAAGRGAVSTENIAFTRWLTHLQNGVLLDEQNCLMLHELWLQSG
                     TGQRRWEGLPDDVRETITVHFTAKRGDWCDIWGSEDVSVWWNRLCDNVVPEKTMPFDL
                     LTVLPTRLDVEVNGFNGGVLNGVPSAYHWYTERYGVKWPCGYDLNISSQGDNCIQVDF
                     DTPWCQPESDVVAALSRRFGCTLEHWYAEQGCNFCGWQLYERGELVDVLWGELEWSSP
                     TDDDELPEVTGPAWIVDKVAHYGG"
     gene            1258..1569
                     /locus_tag="RH288_004524"
     CDS             1258..1569
                     /locus_tag="RH288_004524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033486.1"
                     /translation="MKYDGDGRATARFFSDKGCRRAPLFTAPADAARHKRCLWSVSRV
                     RRARDGRFYRSRLASVTVYASLSPFSDERPSSRFRGIFSPSKRRRLRYSTVGLTRYRT
                     R"
     gene            1646..2329
                     /locus_tag="RH288_004525"
     CDS             1646..2329
                     /locus_tag="RH288_004525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HDV4033487.1"
                     /translation="MSRFVLGNCIDVMARIPDNGIDFILTDPPYLVGFRDRQGRTIAG
                     DKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMAAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYVLAKGRPALPQKPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DDWFMPEAA"
     gene            2330..2551
                     /locus_tag="RH288_004526"
     CDS             2330..2551
                     /locus_tag="RH288_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033488.1"
                     /translation="MNYAGHEKLRAEVAEVANAMCDLRTTMNEMERRYSFNADTLPER
                     LVRQTLFRANRLLMEAYTEILELDSCFKD"
     gene            2563..2997
                     /locus_tag="RH288_004527"
     CDS             2563..2997
                     /locus_tag="RH288_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HDV4033489.1"
                     /translation="MYGTCEILCRELAAKYPADTPLMLVVWSPEEIQALADGMDISLS
                     DHEIRTVLARLEDIPEDQRIESGISSGVAMEIISNVRENRQVTVPAELLASLIQTAEQ
                     ALWKREWAARDNGLAVPECVTRRQAVINQARTLLKNNTHENN"
     gene            3048..3818
                     /locus_tag="RH288_004528"
     CDS             3048..3818
                     /locus_tag="RH288_004528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001523829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033490.1"
                     /translation="MNKTLNALVCRHARNLLLAQGWPEETDVDQRNPNYPGWISIYVR
                     LDAPRLATLLINRHGGVLPPLLASAIQRLTGTGAELVLSGSQWQSLPVLPADGTQVSF
                     PYAGEWLTEDEIRAVLDAVHDAVRSICYQVAEDARRIRAALTTTGQTLLTRQTRRFRL
                     VVKESDHPCWLDEDDENLPVVLDAIVNRGARFSSVEMYLVSDCIEHILSSGLACDVLR
                     IPDEPPRRWFDRGVLREVVREARAEIRSMADALAKIRK"
BASE COUNT          822 a         1071 c         1197 g          849 t
ORIGIN      
        1 cacacagtca aatgtcattg ttgtgactaa aaaacgctca attctctgag tgtgtggctg
       61 tatgcctgct gtgggctgct gtgtccagct tatccacagc attttgtgca cggttctgtg
      121 gacaaaatac ctggttaccc aggccgtgcc ggcacgttaa ccgggctgca tccgatgcaa
      181 gtgtgtcgct gtcgccggcc tcctcacccg gtcacgtttc gtcgttcctc ctccacgcgc
      241 tgcggcttcg gggccgcacc tgcattcgta tgcggtcgcc cggtaacagg tgcggcacgg
      301 cctgatggag gccgcatgtg agaggagaat tcccatgcca aactggtgct cgaatcgtat
      361 gtatttttct ggtgaaccgg cacagatcgc tgagattaaa cgactggcca gcggtgcagt
      421 tacaccgctt tatcgccgcg ccacaaatga aggtattcag ctgtttctgg ccggaagtgc
      481 cggacttctg cagatcactg aaaatatccg ctctgaacag tgccccggag tgacggctgc
      541 cggacgtggt gctgtatcga cggaaaatat cgcgttcacc cgctggctga cacacctgca
      601 gaacggtgta ctgctggatg agcaaaactg cctgatgctg catgaactct ggctgcagag
      661 tggtactgga cagcgtcgct gggaaggatt accggatgat gtcagggaaa ccatcactgt
      721 gcatttcacc gcaaaaagag gtgactggtg tgacatctgg ggtagcgagg atgtatcggt
      781 gtggtggaac cgtctgtgtg acaacgtagt gccggaaaaa accatgccgt ttgacctgct
      841 gacggttctg ccgacccgcc tggatgttga agtgaatggc tttaatggtg gtgttctgaa
      901 cggtgttcct tctgcatatc actggtatac agaacggtat ggcgtgaagt ggccttgtgg
      961 gtatgacctg aatatcagta gtcagggaga caactgcatt caggtggatt tcgacacgcc
     1021 gtggtgtcag ccggaaagcg acgttgttgc agcattaagc cgccgtttcg gctgcacgct
     1081 ggagcactgg tacgccgaac agggctgcaa tttctgtggc tggcagttgt atgagcgcgg
     1141 agagctcgtt gatgtgctct ggggggaact ggaatggtct tccccgacag atgacgatga
     1201 gctgccggaa gtcaccggac ctgcgtggat agtcgacaag gtggcgcatt acgggggatg
     1261 aagtatgacg gagacgggcg ggcaaccgcc cgtttctttt ccgacaaagg atgtcgccgt
     1321 gctcctctgt ttactgcgcc ggctgatgcg gcgcggcata aacgctgcct gtggtcagtg
     1381 tcccgcgtcc ggcgggcacg ggacgggcgc ttttaccgct cccggctggc gtcggtgaca
     1441 gtgtacgcca gcctgtcgcc cttttctgat gaacgccctt caagccgctt tcgcggcata
     1501 ttctcgccgt caaaaagacg acggctgcga tattccacgg tcggcctgac ccgttaccgg
     1561 acgcggtgaa cagcccacag gcagcgggga acgggcacca caggggtgcc ctcccggtgc
     1621 cctctgagaa agaaggagtg ttgttatgtc ccgttttgtc ctcggtaact gcattgatgt
     1681 tatggcgcgt attcctgata acggcattga tttcatactg actgacccgc catacctcgt
     1741 cggttttcgt gaccgacagg ggcgtaccat cgccggcgat aaaaccgatg aatggctgca
     1801 accagcctgt aatgaaatgt atcgcgtact caaaaaagat gcgctgatgg tcagcttcta
     1861 cggctggaac cgcgtcgatc gctttatggc cgcctggaaa aatgcgggat tcagtgtggt
     1921 tgggcacctg gtcttcacca aaaactacac atcgaaggcc gcatatgtgg gttatcgcca
     1981 cgaatgcgcc tacgttctgg caaaaggccg tccggcgctg cctcagaagc cattacccga
     2041 cgtgctgggc tggaaatatt caggcaatcg tcatcacccg acggaaaagc ctgttaccag
     2101 cctgcaacca ctgattgaga gcttcacaca tccgaacgcg attgtgctgg acccgtttgc
     2161 aggcagcggc tcaacctgcg tggctgccct tcagtccgga cgccggtata tcggtatcga
     2221 gctgcttgag cagtatcacc gtgccggaca gcaacgtctg gctgccgtac agcgggccat
     2281 gcagcagggg gccgcaaatg atgactggtt tatgccggag gctgcgtaaa tgaactatgc
     2341 cggacatgaa aaacttcgcg ccgaagtggc ggaggtggcc aatgccatgt gcgacctgcg
     2401 tacaaccatg aatgagatgg agcggcggta cagctttaat gctgacaccc tgccggaacg
     2461 tctggtgcgt cagacgttgt ttcgcgcaaa ccgcctcctg atggaggcat ataccgaaat
     2521 tctggaactg gattcctgct tcaaagattg aggggagaga gtatgtacgg aacatgcgaa
     2581 atactctgcc gggagctggc agcaaagtat ccggcagaca cgccactgat gctggttgtc
     2641 tggtcccctg aagagattca ggccctcgct gacggaatgg atatttccct gtccgatcat
     2701 gaaatcagga ccgtcctggc gcgcctggag gacatcccgg aagaccagcg gattgagtcc
     2761 ggtatttctt ccggcgtggc gatggagatt atcagcaacg tgagagaaaa ccgccaggtg
     2821 accgtccctg ctgaactgct ggcgtccctg attcagaccg ctgaacaggc actgtggaaa
     2881 cgtgaatggg ccgcccgtga taacggcctt gccgtcccgg aatgtgttac ccgccgtcag
     2941 gcagtgatta atcaggcccg caccctgctg aaaaacaaca cacacgaaaa caactgatgt
     3001 tatcgccgcc tgccctgcgg gcggcgatac agggagaacg cttaatcatg aacaaaacgc
     3061 tgaatgcact ggtttgtcgt cacgcccgta acctgctgct ggcgcagggc tggccggaag
     3121 agacggatgt tgaccagcga aatccgaact atccgggctg gatcagcatt tacgtgcggc
     3181 tggatgcgcc ccggctggcg acgttactta tcaaccgtca cggcggcgta ctgccgccgc
     3241 tcctggcctc cgccattcag agactgaccg gaaccggggc ggaactggta ctgtccggca
     3301 gtcagtggca gtcgctgccg gtacttccgg cagacggaac gcaggtgtct ttcccgtatg
     3361 ccggagaatg gctgaccgaa gacgaaatca gggctgttct tgatgcggtg cacgatgcgg
     3421 tacgaagcat ctgttaccag gtggcagaag atgcgcggcg tatccgtgcg gcgctgacca
     3481 ccaccggtca gacgttgctg acccgccaga cgcgccgctt tcgcctggtc gtgaaggaaa
     3541 gcgatcaccc ctgctggctc gatgaagatg acgaaaacct gcccgtggtg ctcgatgcca
     3601 tcgtgaaccg gggagcacgt ttttcgtcgg tggaaatgta cctggtcagc gattgtattg
     3661 agcatatcct gtccagtggg ctggcctgcg atgtgctgcg tataccggat gaaccgcccc
     3721 gccgctggtt tgaccgtggt gttctgcggg aggtggtccg ggaagcccgg gccgaaatcc
     3781 gcagcatggc ggatgccctg gcaaaaatcc ggaaatgatg acactggcgg ggtaaatccc
     3841 cgcctttttc ctgccggtcc ccggacagag cacaaaggaa gtcgccgccg gctccgcttt
     3901 acccggccat gcagggcatg gccttgtggt ttttcagtt
//
LOCUS       DAPHKZ010000228         3797 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.232, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000228 DAPHKZ010000000
VERSION     DAPHKZ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3797
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.232"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..2440)
                     /locus_tag="RH288_004529"
     CDS             complement(<1..2440)
                     /locus_tag="RH288_004529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HDV4033491.1"
                     /translation="MSKFNSITLAILSVLATSHTWAKGETFDTNFMIGGLNGEKISNY
                     HIDSDKPMPGIYAMDVYLNNQWRGHYDIDIKDDPNATCLSMEQLKQIGILTEGISIDK
                     GVECVPLRDAVQGGSVDYDIGHFNLKLSVPQAYVLEYEHGYVPPEAWDRGINALYTSY
                     YASQYYSDYKNGGDDKSSYLNLNSGLNLLGWQLHSNANYTKSDENSGKWKSNTLYLER
                     GIPQILGTFRAGEMYTGSDVFDSVRFRGVRLWRDMQMLPNSKQNFTPVVRGVAQSNAL
                     VTIEQNGFVVYQKEVPPGPFAIDDLQLSNGGADLEVIVKEADGSTSYYRVPYSSVPNM
                     LQPGVSKYEFSAGRSHIEGASNQSDFIQGSYQHGFNNLLTGYGGTLLSDNYSSFVLGT
                     GWNTPIGAISVDFTHSYSKQDNGDVFNGQSYQIAWNKYLSQSGTQFSLAAWRYSSRGY
                     RTFNDHVWANNKNRYNREDNSGYDIANYYQYDFGRKNSFSLNINQSLPENWGYLAISG
                     QWRDYWERSGTGKNYQLSYTNSWERLSYTLSVSQTYDEDNSEDRRINLFFSIPFSWGD
                     NITEKRRDLFISNSTTFDKDGYQSNTTSLSGVAGNRDQFSYGANFSHQQQDSEATAGG
                     NLIWRAPVATIGGSYSQSKKYQQISGNIQGGLVAWSDGIALAPRLSDTFAIVHAPGLD
                     GAAVQGYRYLSTDSRGYAIYDSLTPYRKNTLMLDTSDSQSDVALLGNRKSTAPYRGAV
                     VMTQFDTDKRKPWYFLAQRPDGSPLSFGYEVEDESGKNVGLVGQGSRIFIRTDDVPAS
                     IRVSVNKQQEQFCTI"
     gene            complement(2458..3138)
                     /locus_tag="RH288_004530"
     CDS             complement(2458..3138)
                     /locus_tag="RH288_004530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial assembly chaperone"
                     /protein_id="HDV4033492.1"
                     /translation="MKKLIAFLLTVTVPSAWGGIYIYGTRVIYPEQKKEITVQLMNEG
                     ERSALVQSWIDDGDASLPPEKISVPFVLTPPVVHVSKGEGQQLKIKQLANTLPKDRES
                     LFFLNVLDIPPNSEKYEGKNLIKFAMQNRIKFIYRPKGITRVDKESFSRINIRPVDRG
                     INIKNNSANWITIPELAGNAKINKETLLLAPWSDQTVKTTSVVNYYNITLIDDHGNYL
                     SEKIKTAK"
     gene            complement(3194..3742)
                     /gene="yehD"
                     /locus_tag="RH288_004531"
     CDS             complement(3194..3742)
                     /gene="yehD"
                     /locus_tag="RH288_004531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001603503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein YehD"
                     /protein_id="HDV4033493.1"
                     /translation="MKRSVIAATVLASLFMSAGSFAAEGSTEGQLTINGKVTGTTCQF
                     LSGSENTTISMSEIGRDQFENVEVGSPVTTYSNTTSLPLKVKCPGEKEPRITFSSTQF
                     EGTGSNVTRNTGDASGVGFAVFLGKGTDSSNRISGNSPIKLTPATNGEYELHFTAQYA
                     KAADDVGTGEVSSAITMTVVTD"
BASE COUNT         1052 a          887 c          739 g         1119 t
ORIGIN      
        1 taatagtaca gaattgttcc tgctgtttat taaccgagac gcgaatcgat gcgggaacat
       61 catcagtgcg aataaatatc cgacttccct gtcctaccaa gcccacattc ttaccgcttt
      121 catcttcaac ttcataaccg aacgataatg gagaaccatc cgggcgctga gcaaggaaat
      181 accagggttt acgtttgtca gtatcaaact gcgtcatcac aacggcccca cgataaggag
      241 cggtgctttt acggttgccc agtagtgcca catcgctttg actgtcagaa gtatccagca
      301 tcaacgtgtt tttacgatac ggcgtcaggc tgtcataaat agcgtaacct cggctatccg
      361 tgctcaggta acgatacccc tgtaccgcag ccccatccag ccccggagca tggacgatgg
      421 caaatgtatc tgaaagtctg ggagccagtg ctatcccgtc tgaccacgcg actaaaccac
      481 cttgaatatt accacttatc tgttgatatt ttttcgactg gctatagctg ccaccaatgg
      541 tagccactgg cgcacgccaa atcagatttc cacctgctgt tgcttcgctg tcctgttgtt
      601 gatggctaaa gttagccccg tagctgaact gatcacggtt cccagctaca ccactgaggc
      661 tggtagtatt tgactggtag ccgtctttat caaatgtggt cgagttagag ataaataaat
      721 ctcgtcgttt ttcggtgata ttatcacccc acgagaaggg gattgagaaa aataagttaa
      781 tgcgtctgtc ttcgctgtta tcctcatcgt atgtctggct aaccgacaag gtataactta
      841 gacgttccca tgagttcgta tagcttagtt ggtaattttt ccctgtcccg ctacgttccc
      901 agtaatctcg ccattgaccg ctgatcgcca gataccccca attttccggt aatgactggt
      961 tgatatttaa agaaaagcta ttcttgcgac caaaatcata ctggtagtag ttggcaatgt
     1021 catagcctga gttgtcttct cgattgtatc tatttttgtt atttgcccat acatgatcgt
     1081 taaaagtacg ataaccccga gaggaataac gccaggccgc cagagaaaat tgtgttccgc
     1141 tctgagagag atatttattc caggcaatct gataactttg accgttaaac acatcaccgt
     1201 tgtcttgctt gctgtatgaa tgggtaaaat caaccgatat agcaccaata ggtgtattcc
     1261 atcctgttcc aagaacaaac gatgagtaat tatcagataa cagcgtgccg ccataacctg
     1321 tcagcaaatt gttgaaacca tgctgatagc ttccctggat aaaatcagat tgattgctgg
     1381 ctccttcaat atgactacgt ccggctgaaa attcatattt agaaacgcca ggttgcaaca
     1441 tatttggcac cgatgaataa ggcacccgat agtacgacgt tgaaccatca gcttctttga
     1501 cgataacttc caaatctgcc ccaccattag aaagttgcaa atcatcaatg gcgaatgggc
     1561 ctggcggtac ttctttctgg taaaccacaa aaccattttg ttctatggtg acgagtgcgt
     1621 tactctgggc aacgccgcgt accacaggag taaaattctg tttagagttc ggtaacatct
     1681 gcatatcgcg ccaaaggcgc acgccgcgaa aacgcacgga gtcaaaaaca tcagaaccag
     1741 tatacatttc acctgcgcga aacgtgccga gaatttgtgg aattccacgt tccagatata
     1801 gcgtgttact cttccattta ccgctgtttt cgtcgctttt cgtataattg gcatttgaat
     1861 gcagctgcca gcccaggaga tttaacccac tgttcagatt tagatagcta cttttatcat
     1921 ctccgccgtt tttataatca ctgtaatact gactggcata ataagatgta tataatgcgt
     1981 taatcccgcg atcccatgct tcaggcggaa catagccatg ttcatattcc agaacatagg
     2041 cttggggcac gcttaatttt aggttaaaat gcccaatatc atagtcgacg ctgcctccct
     2101 ggacagcatc ccgaagtggt acacattcta cgcctttatc gatactaatt ccttcagtga
     2161 ggatcccaat ttgctttaat tgctccatgg ataaacatgt tgcattaggg tcatctttaa
     2221 tatcaatatc atagtggcca cgccattgat tattcagata aacatccata gcgtagatac
     2281 ccggcatcgg cttatcacta tcaatatggt agttagaaat tttctcccca tttaaaccac
     2341 caatcataaa attggtatca aacgtttcac ccttagccca tgtatgcgaa gtcgctaata
     2401 ctgacagaat agccagtgta atagaattaa actttgacat aaccaatccc tgataatcta
     2461 tttggcagtt tttatttttt cactcaaata gtttccatga tcatcaatca gagtaatatt
     2521 gtaatagtta acaacggatg tcgttttgac agtctgatct gaccagggtg ccagcagtag
     2581 tgtctcctta ttaattttcg cattcccggc taattcagga atggttatcc agttcgctga
     2641 attatttttt atgttaatgc ctctatcaac gggtctgata ttaatccggg aaaaactctc
     2701 tttatcgact cttgttatac cctttgggcg ataaataaat ttgatacgat tttgcatcgc
     2761 gaatttaatc agattcttgc cttcatattt ctcactatta ggtggaatat ccagtacatt
     2821 aaggaagaac agactttcgc gatctttagg tagagtgttc gccagttgtt taattttcag
     2881 ttgctgtcct tcacccttac taacatgaac taccggtgga gtcagcacaa aaggtacact
     2941 aatcttttcc ggaggaaggc tggcatcgcc atcatcaatc cacgactgaa caagagcact
     3001 acgctcacct tcattcatta actgaactgt aatctctttt ttctgttccg gataaataac
     3061 gcgagtgccg taaatataga taccgcccca cgcagatggg accgttacgg ttagtaagaa
     3121 ggctattaat tttttcatga taacaatcct tgtgattgaa aatcggcgac cgaagccgcc
     3181 gataaacatc atgttaatct gttacaacgg tcattgttat cgcagaacta acttcgccag
     3241 tacccacatc atcagctgct tttgcgtatt gcgccgtaaa atgcaactca tattcaccat
     3301 tagtagctgg tgttaactta ataggactat taccagaaat ccggttgcta gaatcagtac
     3361 ctttccccaa aaaaacagcg aaaccgacac cgctagcatc accagtattg cgagtaacat
     3421 ttgaacccgt tccttcaaat tgggtgctgg agaaggtaat tcttggttct ttttctccgg
     3481 gacatttaac ttttagtggt aaagatgttg tatttgaata agtggtaacg ggggagccaa
     3541 cttctacatt ttcaaattga tcacgaccaa tttcgctcat cgaaattgtt gtattctcac
     3601 taccgctcag gaactgacat gtagtccctg tgactttacc gttaatagtt aactgaccct
     3661 ctgtactccc ttctgctgca aatgatcctg cgctcataaa aagagatgct aatacagtag
     3721 ccgcaataac tgaacgtttc atagtctaat ccttaactaa tttgctttac ctaaaaaaga
     3781 gatcgcaatc tcttgct
//
LOCUS       DAPHKZ010000229         3673 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.233, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000229 DAPHKZ010000000
VERSION     DAPHKZ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3673
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.233"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            320..640
                     /locus_tag="RH288_004532"
     CDS             320..640
                     /locus_tag="RH288_004532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDV4033494.1"
                     /translation="MIAVIFEVQIQPDQQTRYLTLAEELRPLLSHVAGFISIERFQSL
                     ATEGKMLSLSWWENEYAVLQWKNHVLHAKAQQEGRESIFDFYKISIAHITREYSFKKD
                     KDNV"
     gene            633..1019
                     /locus_tag="RH288_004533"
     CDS             633..1019
                     /locus_tag="RH288_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HDV4033495.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKQEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            1027..1713
                     /locus_tag="RH288_004534"
     CDS             1027..1713
                     /locus_tag="RH288_004534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDV4033496.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(1691..2314)
                     /gene="tetR(B)"
                     /locus_tag="RH288_004535"
     CDS             complement(1691..2314)
                     /gene="tetR(B)"
                     /locus_tag="RH288_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HDV4033497.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQTIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            2396..3601
                     /gene="tet(B)"
                     /locus_tag="RH288_004536"
     CDS             2396..3601
                     /gene="tet(B)"
                     /locus_tag="RH288_004536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HDV4033498.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
BASE COUNT         1044 a          658 c          807 g         1164 t
ORIGIN      
        1 taatagggtc ataattttag tgtgatctta atcatgaaat attaaaaaga ttaaaataac
       61 aacaatggta tttaatgatg ggtaaaccta aataccatgc gggatccgca ctattttcgg
      121 tgatagcaaa aaataaaaaa gtataaataa taaacaaaat tataagagaa ggagaacatg
      181 ataagcgcag gccgagcaat ttaaagaagt gtgatataca acataaaaca gcagcatgac
      241 ctttctatat ttcgttgctt atcgaagtgt taattttcgg gtggattact ctgtttgttg
      301 attaataacg gagaaaaata tgattgctgt aatatttgag gtgcaaatac aacccgacca
      361 acaaactcgc tatttgactt tagctgagga gttaagacca ctattaagtc atgtagctgg
      421 ttttatttca attgaacgtt ttcaaagtct agctacagaa ggaaaaatgt tatcgctatc
      481 ttggtgggaa aacgaatacg cagttctgca atggaaaaat catgttttac atgcgaaagc
      541 tcaacaagaa gggcgagagt caatatttga tttttacaaa attagtattg ctcatattac
      601 tcgcgaatat tcatttaaaa aggacaagga taatgtttga tgttcacgtt gttttagata
      661 atcaaatagg acaattagca ttactaggaa aaacattagg taataaaggt attggattgg
      721 aagggggagg gatatttacg gttggtgatg aatgccatgc tcattttctt gttgaacaag
      781 gaaaggaagc taaaatagcg ctagagcaag ctggactgtt agtacttgcg atccggacac
      841 cattaattcg taagttaaaa caggaaaaac cgggggaact tggcgaaata gcacgagtat
      901 tggcggagaa taacattaat attttagtgc aatacagtga ccatgctaac caactgatat
      961 taataacgga caatgatagt atggctgcat ctgttacgct cccttgggca ataaagtgaa
     1021 cttgcgatgg ctaatttaat acgaaaagag gttacctttg agtcctcaat agccgcgata
     1081 ggggcggcta tgtctgacat ttcacgagtt aaaatactca gtgctttgat ggatgggcga
     1141 gcttggacgg ccactgagct aagttctgtg gcgaatatat cagcttcaac ggcgagcagt
     1201 catttatcta aattattaga ttgccagcta atcacagtag tagctcaagg caagcatcgt
     1261 tattttcggc tagcaggaaa agatattgct gaattgatgg aaagtatgat ggggatctcc
     1321 ttaaaccatg gcgtacatgc caaagtttcc acgccagtgc atttacgaaa agcacgtact
     1381 tgctatgatc atttagctgg cgaagttgcc gttaagatct atgattccct ttgtcaacag
     1441 caatggatca ctgaaaatgg ttcaatgatc acattaagtg gtattcaata ttttcatgaa
     1501 atgggaattg acgttccttc caaacattca cgtaaaatct gttgtgcgtg tttagattgg
     1561 agtgaacgcc gtttccattt aggtgggtac gttggagccg cattattttc gctttatgaa
     1621 tctaaagggt ggttaactcg acatcttggt taccgtgaag ttaccatcac ggaaaaaggt
     1681 tatgctgctt ttaagaccca ctttcacatt taagttgttt ttctaatccg catatgatca
     1741 attcaaggcc gaataagaag gctggctctg caccttggtg atcaaataat tcgatagttt
     1801 gtcgtaataa tggcggcata ctatcagtag taggtgtttc cctttcttct ttagcgactt
     1861 gatgctcttg atcttccaat acgcaaccta aagtaaaatg ccccacagcg ctgagtgcat
     1921 ataatgcatt ctctagtgaa aaaccttgtt ggcataaaaa ggctaattga ttttcgagag
     1981 tttcatactg tttttctgta ggccgtgtac ctaaatgtac ttttgctcca tcgcgatgac
     2041 ttagtaaagc acatctaaaa cttttagcgt tattacgtaa aaaatcttgc cagctttccc
     2101 cttctaaagg gcaaaagtga gtatggtgcc tatctaacat ctcaatggct aaggcgtcga
     2161 gcaaagcccg cttatttttt acatgccaat acaatgtagg ctgctctaca cctagcttct
     2221 gggcgagttt acgggttgtt aaaccttcga ttccgacctc attaagcagc tctaatgcgc
     2281 tgttaatcac tttactttta tctaatctag acatcattaa ttcctaattt ttgttgacac
     2341 tctatcattg atagagttat tttaccactc cctatcagtg atagagaaaa gtgaaatgaa
     2401 tagttcgaca aagatcgcat tggtaattac gttactcgat gccatgggga ttggccttat
     2461 catgccagtc ttgccaacgt tattacgtga atttattgct tcggaagata tcgctaacca
     2521 ctttggcgta ttgcttgcac tttatgcgtt aatgcaggtt atctttgctc cttggcttgg
     2581 aaaaatgtct gaccgatttg gtcggcgccc agtgctgttg ttgtcattaa taggcgcatc
     2641 gctggattac ttattgctgg ctttttcaag tgcgctttgg atgctgtatt taggccgttt
     2701 gctttcaggg atcacaggag ctactggggc tgtcgcggca tcggtcattg ccgataccac
     2761 ctcagcttct caacgcgtga agtggttcgg ttggttaggg gcaagttttg ggcttggttt
     2821 aatagcgggg cctattattg gtggttttgc aggagagatt tcaccgcata gtcccttttt
     2881 tatcgctgcg ttgctaaata ttgtcgcttt ccttgtggtt atgttttggt tccgtgaaac
     2941 caaaaataca cgtgataata cagataccga agtaggggtt gagacgcaat cgaattcggt
     3001 atacatcact ttatttaaaa cgatgcccat tttgttgatt atttattttt cagcgcaatt
     3061 gataggccaa attcccgcaa cggtgtgggt gctatttacc gaaaatcgtt ttggatggaa
     3121 tagcatgatg gttggctttt cattagcggg tcttggtctt ttacactcag tattccaagc
     3181 ctttgtggca ggaagaatag ccactaaatg gggcgaaaaa acggcagtac tgctcggatt
     3241 tattgcagat agtagtgcat ttgccttttt agcgtttata tctgaaggtt ggttagtttt
     3301 ccctgtttta attttattgg ctggtggtgg gatcgcttta cctgcattac agggagtgat
     3361 gtctatccaa acaaagagtc atcagcaagg tgctttacag ggattattgg tgagccttac
     3421 caatgcaacc ggtgttattg gcccattact gtttgctgtt atttataatc attcactacc
     3481 aatttgggat ggctggattt ggattattgg tttagcgttt tactgtatta ttatcctgct
     3541 atcgatgacc ttcatgttaa cccctcaagc tcaggggagt aaacaggaga caagtgctta
     3601 gttatttcgt caccaaatga tgttattccg cgaaatataa tgaccctctt gataacccaa
     3661 gagggcattt ttt
//
LOCUS       DAPHKZ010000230         3636 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.234, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000230 DAPHKZ010000000
VERSION     DAPHKZ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3636
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.234"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..141
                     /locus_tag="RH288_004537"
     CDS             <1..141
                     /locus_tag="RH288_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033499.1"
                     /translation="HVKNIIPIITATLILNYLNNSERSLVKQILIEDEIIVCATYLIP
                     DI"
     gene            143..487
                     /locus_tag="RH288_004538"
     CDS             143..487
                     /locus_tag="RH288_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415690.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper family protein"
                     /protein_id="HDV4033500.1"
                     /translation="MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNG
                     VNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVI
                     GGTGGAILGKMK"
     gene            491..826
                     /locus_tag="RH288_004539"
     CDS             491..826
                     /locus_tag="RH288_004539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmgD family protein"
                     /protein_id="HDV4033501.1"
                     /translation="MMMKKFALLAGLFVFAPMTWAQDYNIKNGLPSETYITCAEANEM
                     AKTDSAQVAEIVAVMGNASVASRDLKIEQSPELSAKVVEKLNQVCAKDPQMLLITAID
                     DTMRAIGKK"
     gene            complement(883..3531)
                     /locus_tag="RH288_004540"
                     /pseudo
     CDS             complement(883..3531)
                     /locus_tag="RH288_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768542.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
BASE COUNT          994 a          845 c          743 g         1054 t
ORIGIN      
        1 cacgtaaaaa acataattcc tatcatcaca gccacgctca ttttgaatta tctgaataat
       61 agcgagcgtt ctttagttaa gcagatctta attgaagacg aaattattgt gtgtgcaact
      121 tacttaatac cggacatcta agttgaagaa aaaaatactt gccttcgggc ttatctcagc
      181 attgttctgc tccacgccag cgatggcgga tatgaaccgc accacgaaag gtgcattgct
      241 aggcgcaggc gttggtttac ttactggcaa tggtgttaat ggcgtactga aaggtgcagc
      301 tgttggcgct ggtgttggtg cagtaacaga aaaaggccgc gacggtaaaa atgcgcgtaa
      361 aggtgcaaaa gtgggtgccg ccgttggtgc tgtcactggc gttctgaccg gcaatggcct
      421 cgaaggggcg attaaaggtg ccgtgattgg cggtacgggt ggtgcaattc tgggtaaaat
      481 gaaataagga atgatgatga aaaaatttgc tttactggcg ggcctgtttg ttttcgcacc
      541 aatgacctgg gcgcaggact acaatattaa aaacggtttg ccgtcagaaa cctatattac
      601 ttgcgcagaa gccaacgaaa tggcaaaaac tgacagcgca caagttgcag aaattgttgc
      661 ggtaatgggt aatgccagcg ttgccagccg tgatttaaaa attgagcaat ctccggaact
      721 gagcgccaaa gtggtagaaa aactgaatca ggtttgcgct aaagacccgc aaatgctgtt
      781 gatcacggca attgatgaca ccatgcgtgc tatcggcaaa aaataatatt tcatatgtac
      841 cgcgtcgatg aatacgacgc ggttttttag ctaacggcgg gatcagaact tatatttcag
      901 gcccaccatc actgcggtgt cattgtagcc attatcaccc agctgcacgc ccacattccc
      961 cagacgctgg ccgctggatt caggttgcca tttacgccaa gtttaatttc ccccaaatta
     1021 ctcgccccat cttgttcgac tttcacaccg ttcattgaga cagcaaaatc tttactgtta
     1081 tggatccagt tcatttcaac aaaaggttca aagtcgtcac cgtgcggacc gctgtttttc
     1141 tcctgagtac gaataaaggt gcggaagccg agtcgggtct ggatgttgtt atttgcgtca
     1201 ttctcaatac gtgagccatt ggcttccgtg tgcgcattat gatcgacgcc catccagata
     1261 gcctgtgcct gtggctggaa gatccacgta tatttcgccg cttccagacc aaaggattta
     1321 ttcagggcaa aaccgtaacc cgcttccagc gagacggttg cacctttcgc gctataggat
     1381 tcataggcta attcatcccc tttcaccgag tttttaaacc agctatattg cgcccaggag
     1441 tcaatgtatg cgcctttttt actgatgtca tcggcaaacc aggtggcata cagccctgcg
     1501 ctatagcctc tgacactccc tttcgaacga taatccgaca cgctggaatg agttaagttg
     1561 tagtcgcggg cataaccagc catcactccc aaacgccaac tgtcactatc ggtaaaacca
     1621 ccggttaaca gatcgccccc taactgcgag acgtagcgat gcgaggtcgt tctcaactgt
     1681 ccgttgctgt cacgccaggc attatgcccg ccaatttgac gtagccaaag tcggcttgaa
     1741 cgctcctgtt cagttacagg atcgatgtag cgcgtttcac ccgcacggtc gttcagacgc
     1801 ataacaaaaa gagtgttagc agctgccagg ttagcgacgt aacttccagc ttcggggcgc
     1861 aggacggggg taggcgtttc tgttgattct gaatttccct ctgagctgtt atcctcctca
     1921 ttcactgact gataacttgt caaataccag tttttgcctt gttgttttag ttgatattcg
     1981 aaagctccag ctgcaatcct tgcatcacct tatctgaagg catctgctgg agattcatcg
     2041 ccattcacag ttatgagttc gatcccgttt agcgtggccg cgccgcttcc tccagcattt
     2101 ttcacataga cggtagttga acccgaagta ttaccctcaa caataagtct gtccgtagcc
     2161 gatttatcat cacctaatac ggtgcggata ttaagctgac cattattacc gacataatta
     2221 ccttttacgg ttaatgtttt tccttgggta aatgtttgac catcatcata cgaaagattg
     2281 ataatactgt ctgaattagt cagatgggta acaacggagt catctttcat attccagatt
     2341 gtattttctg aaagcttcag cgtggttgtg ccgctgacga gtttagtcgc tccatttaga
     2401 atagagtcgg acgaaattat gtttaagtca cctccagtat tattaaccag aacattatta
     2461 ccaggtgtga taatacttcg attaaggata cttacatccg ttgtagtttt gttaacatca
     2521 atactatcca aagcacttga aagttcaaca cttaatagtg ctattttggc ttgagaatcg
     2581 atatttgatg catcaattga tattccttta tcttgttttg ataccgcgat gacattggaa
     2641 aaaaaataac tctccaccat tgtatatttt tgcaatgggg gctttagtgc ctgttgttgt
     2701 aatagaacta ttttttatat caatgttacc ttgtcgaata gcaactgcat aacttccatc
     2761 agccacagtt tcaagtgcca cataatctaa attaatatat gcttttttcc cattagcata
     2821 agcaccatag ctattaatgc cattagttgt tatggaacca ccattcattt ttaaatcagc
     2881 acggctaata acttcgtaac tgttagaatc actaacttca tcatctacag catcgacaca
     2941 tgttcgagac tctccaggac ttgaacatgc aagaacacct actgcatttt ccccagaggt
     3001 aacaatgttc gttttatctg tggtttcaag acgggtgtta tttaccatct tttcagaatc
     3061 attaacctgg cttaaaagtc ccgctgaata tgccccaccc gactcgactg aattatcacc
     3121 attcataaag atggtgccac caaattcact gactactgcg ctggctgtta tccctccatt
     3181 ttctttgtca gatacgcttc cagaggtctt aatatcgcta tcgcttatat ataatacttt
     3241 gttttgacta tcaacagaaa taccataaga tccatcacca ctagtcatca cactggcatt
     3301 atttatatat ccagttacac cgtcatccac tttcacagca tggctttcgt cttcagtggt
     3361 tagatactct ccattactta tcggattatt atctttgatt tcaatcggcg attcttcatc
     3421 agtcatatag gaaattatac tataatcatc caacaattgt gttgcatatg cattacccac
     3481 cgccagagca ataagtccca aactaaaccc ggggagtttt ttcagtttca tagattaacc
     3541 atccattcat tggattaaca aacattcctg gtcaaataac ctatgagctc agattaccaa
     3601 aacggagggt aaagacaaaa acaaaagcac aaaaaa
//
LOCUS       DAPHKZ010000231         3616 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.235, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000231 DAPHKZ010000000
VERSION     DAPHKZ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3616
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.235"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..819)
                     /locus_tag="RH288_004541"
     CDS             complement(<1..819)
                     /locus_tag="RH288_004541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001691087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4033502.1"
                     /translation="MTVKYYAILTNQGAARLANATMLGSKLNLTQMAVGDANGVLPTP
                     DPAQTKLINQKRIAPLNLLSVDPNNQSQIIAEQIIPENEGGFWIREIGLYDDEGVLIA
                     VANCPETYKPQLQEGSGRTQTIRMILVVTNTEAITLKIDPSVVLATRKYVDDEVLELR
                     LYVDDQMRNHIAAQDPHTQYAQKHNPTFTGEPKAPTPTAGNNTTRIATTAFVQDAITA
                     LINGAPATMDTLKEIAAAINNDPKFSTTINNALEGKQPLDNTLTNLSGKDVPSLL"
     gene            complement(816..1427)
                     /locus_tag="RH288_004542"
     CDS             complement(816..1427)
                     /locus_tag="RH288_004542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HDV4033503.1"
                     /translation="MSDSRLLPTGSSLLEVAAAKACAEIEKTPVSIRELWNPDTCPAN
                     LLPWLAWSFSVDRWDDKWPEATKRAVIRDAYFIHCHKGTIGAIRRVVEPLGYLIEVRE
                     WWQLNEEPGTFRIVVGVLEQGITEEMYQELERLVADAKPASRHLTGLAISLSTTGNIF
                     AGAGCYHGDALTVYPYTPEAIIVGGDYFPASAIHLIDNLRVNA"
     gene            complement(1420..2328)
                     /locus_tag="RH288_004543"
     CDS             complement(1420..2328)
                     /locus_tag="RH288_004543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001121472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate assembly protein"
                     /protein_id="HDV4033504.1"
                     /translation="MLIIDLNQLPAPDVVEELDFETILAERKATLISLYPEDQQEAVA
                     RTLTLESEPLVKLLEENAYRELIWRQRVNEAARAVMLACAAGNDLDVIGANYNTTRLI
                     ITPADDSTIPPTPAVMESDTDYRLRIQQAFEGLSVAGSVGAYQYHGRSADGRVADISV
                     TSPSPACVTISVLSRENNGVASEDLLAVVRNALNGEDVRPVADRVTVQSAAIVEYQIN
                     ATLYLYPGPESEPIRAAAVKKLEAYITAQHRLGRDIRLSAIYAALHVEGVQRVELTAP
                     LADIVLNSTQASFCTEYSVVTGGSDE"
     gene            complement(2333..2680)
                     /locus_tag="RH288_004544"
     CDS             complement(2333..2680)
                     /locus_tag="RH288_004544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HDV4033505.1"
                     /translation="MTARYLGMNRSDGLTVTDLEHISQSIGDILRTPVGSRVMRRDYG
                     SLLASMIDQPQTPALELQIKVACYMAVLKWEPRVTLSSVTTERSFDGRMTVMLTGQHN
                     DTGQPLSLTIPVS"
     gene            complement(2677..3312)
                     /locus_tag="RH288_004545"
     CDS             complement(2677..3312)
                     /locus_tag="RH288_004545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HDV4033506.1"
                     /translation="MKTLANIQELARALRNMIRPGIIVETDLNAGRCRVQTGGMCTDW
                     LQWLTHRAGRSRTWWAPSVGEQVLILAVGGELDTAFVLPGIYSGDNPAPSASADALHI
                     RFPDGAVIEYEPETSALTVSGIKTASVTASDSVTATVPVVMVKASTRITLDTPEVVCT
                     NRLITGTLEVQKGGTMRGNIEHTGGELSSNGKVLHTHKHPGDSGGTTGGPL"
BASE COUNT          821 a          991 c          955 g          849 t
ORIGIN      
        1 gagaagacta ggtacatcct ttccactcaa attagtcagc gtattgtcca gcggttgttt
       61 accttccagc gcattgttaa tggtggtgct gaatttcggg tcattgttaa tggctgcggc
      121 aatttctttc agtgtatcca tcgtggcagg cgcaccgtta atcagagcgg taatagcgtc
      181 ctgaacaaac gcagtagtcg caatccgcgt ggtgttattt cctgcggtag gtgtcggcgc
      241 ttttggttct ccggtaaatg tcggattatg tttctgtgca tactgggtat gaggatcctg
      301 tgcggcaatg tggtttctca tctggtcatc cacatacagc cttaattcca ggacttcatc
      361 atccacgtat ttacgggtcg ccagtaccac cgacgggtca attttcagcg taatagcttc
      421 ggtattcgtg acaaccagaa tcatgcggat agtctgggta cgaccgctgc cttcctgcaa
      481 ctgcggtttg tacgtttccg ggcagttcgc caccgcaatg agtacgcctt catcatcgta
      541 aagcccaatc tcacggatcc agaatcctcc ctcgttctca ggaataattt gctccgcaat
      601 aatctggctc tggttgttcg ggtcaacact cagaagattc agcggcgcga tgcgtttctg
      661 gttaatcagt tttgtctgtg ccgggtctgg tgtcggcaag acaccattcg catcaccaac
      721 ggccatttgc gtcagattca gcttactgcc gagcatcgtc gcgttagcca gccgtgctgc
      781 gccctgatta gtcagaatgg cgtagtattt cactgtcatg cgtttactct caggttatca
      841 attaaatgaa tggccgaggc cgggaaataa tcccctccga caataatggc ctccggggtg
      901 tagggataaa ccgtcagggc gtcgccgtga tagcatcccg caccggcaaa aatgttgccg
      961 gttgtactta aactgatagc cagtcccgtc agatggcggc ttgccggttt tgcatcagca
     1021 acgaggcgct ccagctcctg atacatttct tcggtgatac cctgctcaag cacgccaaca
     1081 acgatacgga acgtccccgg ctcctcgttg agctgccacc actccctcac ctcaatcaga
     1141 tagccgagcg gctccaccac acgccggatt gcacctatag tgcctttatg acagtgaatg
     1201 aaatacgcat cgcggataac agcgcgtttt gtcgcttccg gccacttatc atcccagcgg
     1261 tcaaccgaaa atgaccacgc cagccacggc agcagatttg ccgggcaggt atccgggttc
     1321 cacagctcac gaatactgac cggcgttttt tcaatttccg cacaggcttt tgcggcggca
     1381 acttcaagca gtgatgagcc ggtcggcagc agtcgcgaat cactcatccg agcctccggt
     1441 cacgacgctg tattcggtgc agaaagacgc ctgcgtactg ttgagcacga tgtcagccag
     1501 cggtgcagtc agttcgacac gctgcacgcc ttccacatgc aaagcggcat aaatggcaga
     1561 cagacggatg tcgcgcccca gccggtgctg tgccgtgatg tatgcttcca gttttttcac
     1621 ggcggccgcg cggatgggtt cgctttcggg accagggtaa aggtaaagcg tggcgtttat
     1681 ctggtattca acgatggcgg cagactgcac ggtcacgcgg tcggcaaccg gcctgacgtc
     1741 ctcgccatta agggcgttac gcaccacagc cagcaggtct tcggatgcga cgccgttatt
     1801 ttcacgtgac agcacagaga tagtgacaca ggcaggagac ggactggtga cagaaatatc
     1861 ggcgacacgc ccgtcagcac tgcgaccatg atactgatag gctcccactg acccggcgac
     1921 gcttaagccc tcaaaagcct gctgaatacg cagacgataa tcggtgtcag attccatcac
     1981 tgccggtgtc ggcggaatgg tcgaatcatc tgccggggtg ataatcaggc gcgtggtgtt
     2041 gtaattggca ccaattacat caaggtcatt accggcagca caggccagca tcaccgcccg
     2101 tgcggcctca ttcacacgct gacgccagat aagctcacga taagcatttt cctccagcag
     2161 tttaacgaga ggctcagatt ccagcgtcag ggtacgggcg accgcctcct gctggtcttc
     2221 cgggtaaagg gaaatcagtg tcgccttgcg ttcggcaaga atggtttcaa agtccagctc
     2281 ctcgaccaca tccggtgcgg gtagctggtt caggtcgata atcagcatgg tttcaactca
     2341 cagggatggt taacgaaagt ggctggccgg tgtcgttgtg ctggccggtt aacatgaccg
     2401 tcattcgccc gtcaaaactg cgctcagtgg tgacggatga cagggtgacg cggggttccc
     2461 atttcagcac cgccatgtaa caggcgacct taatctgcaa ctcaagcgcc ggggtctgcg
     2521 gctggtcaat cattgatgcc agcaacgagc cgtaatcacg acgcatcacc cgtgaaccga
     2581 ccggtgtgcg caggatatcg ccgatactct ggctgatatg ctcaaggtca gtgacagtca
     2641 ggccatcact gcgattcatt ccgagataac gcgctgtcat agaggtcccc ctgttgtgcc
     2701 gccactgtcg ccggggtgtt tatgggtatg cagtacctta ccgtttgatg agagttcacc
     2761 gccggtgtgt tcaatgttgc cgcgcatcgt cccgcccttc tgcacttcca gcgtgccggt
     2821 aatcagcctg ttggtgcaga ctacctccgg tgtgtccagg gtgatgcggg ttgacgcttt
     2881 caccatgacc accggcaccg tggcagtaac agaatcagaa gccgtcacgc tggccgtttt
     2941 aattccgctt accgtaagtg cactggtttc gggttcatac tcaatcaccg ccccgtcagg
     3001 gaaacggata tgcagggcat ccgccgacgc agacggcgcg gggttatcgc cggaataaat
     3061 ccccggcaga acgaacgccg tgtcgagttc accgcccacg gccagaatca gcacctgctc
     3121 ccccacggaa ggtgcccacc atgtgcgcga acgtccggca cgatgggtca gccactgaag
     3181 ccagtcggtg cacatgccgc cggtctgcac acggcagcga ccggcgttaa ggtcggtttc
     3241 gacgataatg ccggggcgta tcatgttgcg cagtgcgcgc gcgagttcct ggatatttgc
     3301 gagtgttttc ataagatcta gcatgctgct gagaactgat gagaacaata aaagagtgtt
     3361 tttctaaggt tgacacaaca ctccatttga agtgaatata atgattactt aactggcaaa
     3421 aaaacatcct cactaattgg agccaatgga tacacgcatg tcagacattc taattactta
     3481 tgatgaacgg aaagataaat ttgagtccta tgcccttact cttaaatcgt tattaaccac
     3541 gttaattcgc aatgaaaaaa tttcaattca ctcacttgaa tcaagagtta aaacaaaaaa
     3601 aagccttgaa ggtaag
//
LOCUS       DAPHKZ010000232         3551 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.236, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000232 DAPHKZ010000000
VERSION     DAPHKZ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3551
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.236"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..243)
                     /locus_tag="RH288_004546"
     CDS             complement(<1..243)
                     /locus_tag="RH288_004546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YmgA"
                     /protein_id="HDV4033507.1"
                     /translation="MKTSDNERIKYEITGQAVLQILRMKINFSLQTLIKQLLVMKSAE
                     EDAFRRDLIDSIIRDFSNSDSGGPNRRTATADNKSMF"
     gene            complement(286..522)
                     /locus_tag="RH288_004547"
     CDS             complement(286..522)
                     /locus_tag="RH288_004547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YcgZ"
                     /protein_id="HDV4033508.1"
                     /translation="MHQNSVTLDSAGAITRYFAKANLHTQQETLGEIVTEILKDGRNL
                     SRKSLCAKLLCRLEHATGEEEQKHYNALIGLLFE"
     gene            836..2047
                     /gene="bluF"
                     /locus_tag="RH288_004548"
     CDS             836..2047
                     /gene="bluF"
                     /locus_tag="RH288_004548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blue light-responsive regulator BluF"
                     /protein_id="HDV4033509.1"
                     /translation="MLTTLIYRSHIRDDEPVKKIEEMVSIANRRNMQSDVTGILLFNG
                     SHFFQLLEGPEEQVKMIYRAICQDPRHYNIVELLCDYAPARRFGKAGMELFDLRLHER
                     DDVLQAVFDKGTSKFQLTYDDRALQFFRTFVLATEQSTYFEIPAEDSWLFIADGSDKE
                     LDSCALSPTINDHFAFHPIVDPLSRRIIAFEAIVQKNEDSPSAIAVGQRKDGEIYTAD
                     LKSKALAFTMAHALELGDKMISINLLPMTLVNEPDAVSFLLNEIKANALVPEQIIVEF
                     TESEVISRFDEFAEAIKSLKAAGISVAIDHFGAGFAGLLLLSRFQPDRIKISQELITN
                     VHKSGPRQAIIQAIIKCCTSLEIQVSAMGVATPEEWMWLESAGIEMFQGDLFAKAKLN
                     GIPSIAWPEKK"
     gene            2252..2983
                     /gene="bluR"
                     /locus_tag="RH288_004549"
     CDS             2252..2983
                     /gene="bluR"
                     /locus_tag="RH288_004549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor BluR"
                     /protein_id="HDV4033510.1"
                     /translation="MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDE
                     EDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRA
                     RIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAATSLFEMRRK
                     PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPHPELFPTQTLIVWTGM
                     APTRRQNELLQHWGEQGYKVIFHAP"
     gene            3204..>3551
                     /locus_tag="RH288_004550"
     CDS             3204..>3551
                     /locus_tag="RH288_004550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 family protein"
                     /protein_id="HDV4033511.1"
                     /translation="MDQVVVFQKMFEQVRKEQNFSWFYSELKHHRIAHYIYYLATDNI
                     RIITHDDTVLLLRGTRNLLKVSTTKNPAKIKEAALLHICGKSTFREYCSTLAGAGVFR
                     WVTDVNHNKRSYYA"
BASE COUNT         1037 a          754 c          737 g         1023 t
ORIGIN      
        1 gaacatactt ttattgtcag ctgtcgctgt tcttcggttt ggccctcctg aatcactatt
       61 gctaaaatca cgaattatgc tgtcaattaa atcgcgtcgg aaagcatctt cctcagccga
      121 tttcattacg agtaattgct taataagagt ctgcaatgaa aaatttatct tcatgcgcag
      181 tatctggagc accgcctggc cagtaatttc atattttata cgttcattat cagatgtctt
      241 cataacgact tcatagctaa cctgttaaat aatcaggctg ttgcattatt caaaaagcaa
      301 cccaattagt gcattataat gtttctgttc ctcttcccca gtcgcgtgtt ccagtcggca
      361 aagaagtttg gcacaaagcg actttcgact cagattacgt ccatctttca aaatctcagt
      421 cacaatttcc ccgagagttt cctgctgagt atgcaagtta gcttttgcaa agtaacgagt
      481 gattgctccc gcagaatcta aagtcactga attttgatgc atgctacgcc tctgttaaaa
      541 atgttaatca atgttaagtg aagtaacaat agcaaacttg tacgaaatat gtgtacagaa
      601 tgataaatta attttttgca attagtgcta atgcatataa aacaatgtgt tatgataaaa
      661 catattgcat catttaactg acaatctata caagattttt cgccaactag tgttcaactt
      721 tttccatttt ttatcaatgt aaagaaacgg ttatgttttg gtattaaaag aaagacacaa
      781 gaagatatgt ctgttaccgt cttactctcg cctcacccat taccctggat tgttaatgct
      841 taccaccctt atttatcgta gccatatacg tgacgacgaa cctgtcaaaa aaatcgaaga
      901 aatggtttcg atagcaaatc gcaggaacat gcagtctgac gtaacaggga tcttactgtt
      961 taatggttct cattttttcc agcttctgga aggtccggaa gaacaggtta aaatgatata
     1021 tcgggctata tgccaggatc cacggcacta taatattgtt gagctgctgt gcgattacgc
     1081 gcctgctcgc cgttttggca aagcgggaat ggaattattt gatttgcgcc tgcacgagcg
     1141 agatgacgtt ttacaggccg tattcgacaa aggcacatca aaatttcagc taacttatga
     1201 tgacagagcg ctacaatttt ttcgtacttt tgtccttgca accgaacaat caacctattt
     1261 cgagatccct gccgaagact cctggctttt tatcgctgac ggatctgata aagaacttga
     1321 ttcctgtgcc ctttcaccaa ctataaacga ccactttgcc tttcatccta ttgtcgatcc
     1381 cttatcgcgg cggataatcg cttttgaagc cattgtgcaa aaaaatgaag atagcccatc
     1441 agccatagcg gttgggcagc gtaaagacgg ggaaatctac acagcggatc tcaaaagtaa
     1501 ggcgcttgca ttcacgatgg cacacgcact tgagctcggt gataaaatga tttcaatcaa
     1561 tctattacct atgaccctgg ttaacgaacc tgacgcagtc tcttttttac ttaatgaaat
     1621 aaaggccaat gctctggtgc ctgaacaaat catcgttgaa tttactgaaa gtgaagtcat
     1681 atctcggttt gatgagtttg ccgaagcgat taaatcgcta aaggctgctg gtatcagtgt
     1741 agcaattgat cattttggcg caggttttgc tggtttgtta ctcctgtcac gcttccagcc
     1801 tgacagaatt aaaatcagtc aggaattgat taccaatgtt cataaaagtg ggccacggca
     1861 ggcaattatt caggcgatca taaaatgctg tacatcactt gaaattcaag tcagtgctat
     1921 gggcgtggca acaccagaag agtggatgtg gcttgaatcc gcaggaattg agatgtttca
     1981 gggagatctg tttgctaaag ctaaattgaa tggtatccct tccatagcgt ggccagagaa
     2041 aaaataattt tcagcacatt ctttcacatg atttcagtaa atcatcgtga aaatgaatac
     2101 gttacgttta aatttaatcc acattaaaaa taatgtttca tccaatttag ctgaaatctt
     2161 atttatactt tgtacaattt tagcgtatat tgtacaaagt attattgggt cgtgtacagg
     2221 cgacggagat ttgtgaccgc aaggaggaat tgtggcttat tacagcattg gtgatgttgc
     2281 tgaacgttgc gggattaatc ctgtcactct ccgggcctgg caacgccgct acggtttgtt
     2341 aaaaccacag cgcagtgaag gcggacaccg actctttgat gaagaagaca tacaacgcat
     2401 cgaagagatc aagcgttgga taagtaatgg cgtccctgta ggcaaagtta aagcattact
     2461 ggaaaccacc agccaggata cggaagatga ctggagccgc ctgcaagaag agatgatgtc
     2521 aattcttcgc atggctaatc ctgccaaact acgcgcgaga attatttcac tgggtcgaga
     2581 gtacccagta gatcaattga ttaatcatgt ttaccttcct gttcgccagc gtctcgtgct
     2641 tgatcacaac acctcccgca ttatgagcag tatgtttgac ggcgcattaa ttgaatacgc
     2701 agcaacctcg cttttcgaaa tgcgccgtaa gcccggtaaa gaagccattc tgatggcgtg
     2761 gaatgttgaa gagagagcac gattgtggct ggaagcatgg cgtttatcat tgtcaggatg
     2821 gcacatttct gttcttgctg atcccattga atcgccgcac ccggaactgt tcccgacgca
     2881 aacattgatt gtctggacag gcatggcacc aacgagaagg caaaacgaac ttttacaaca
     2941 ctggggtgag caaggttata aagtcatctt tcatgccccc taatttcacc tttatcccgc
     3001 cccttagaca gaatgttata atctgaaccc acaacagcgt ttgtaccgga gctggtccgt
     3061 tgcaaaatgc tcaccgggag aattcagata ttccctctat cacactctgt acatatcaca
     3121 gccaaaggac agaccagatt gaagtggtaa aaccgatcgt gcacactacg cagtctcaca
     3181 actaacaaga ggttattatc ctgatggatc aggtcgttgt ttttcaaaag atgtttgagc
     3241 aagtgagaaa agagcaaaac ttctcctggt tttattcaga attaaaacat caccgtattg
     3301 cacattacat ttattatctg gctacggata acatcagaat tattactcac gatgatacgg
     3361 ttttgttatt aagaggaacc aggaacctgt taaaagttag tacgaccaag aaccctgcta
     3421 aaataaaaga ggccgcattg cttcatattt gcggaaaatc tacatttcgg gaatactgtt
     3481 caacactggc aggcgcgggc gttttccggt gggttactga tgttaatcat aacaaacgca
     3541 gttactacgc c
//
LOCUS       DAPHKZ010000233         3532 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.238, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000233 DAPHKZ010000000
VERSION     DAPHKZ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3532
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.238"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(567..932)
                     /locus_tag="RH288_004551"
                     /pseudo
     CDS             complement(567..932)
                     /locus_tag="RH288_004551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014543172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(1048..2142)
                     /gene="mnmH"
                     /locus_tag="RH288_004552"
     CDS             complement(1048..2142)
                     /gene="mnmH"
                     /locus_tag="RH288_004552"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDV4033512.1"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEHGAMPAAINLPLMN
                     NDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQ
                     RSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDES
                     RMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKAR"
     gene            complement(2211..3137)
                     /gene="allS"
                     /locus_tag="RH288_004553"
     CDS             complement(2211..3137)
                     /gene="allS"
                     /locus_tag="RH288_004553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HDV4033513.1"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS"
     gene            3367..>3532
                     /locus_tag="RH288_004554"
     CDS             3367..>3532
                     /locus_tag="RH288_004554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HDV4033514.1"
                     /translation="MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALV
                     EILEQDRTLIS"
BASE COUNT          878 a          901 c          847 g          906 t
ORIGIN      
        1 tataacaaat attggagctg gattgcctga tgcttgtgca gagtaattgc ttgaattaag
       61 agtctatccc atatcgaagt cgtcaacttc gtagtgagga aaagtaaaat tcctgactga
      121 gaaaagacat gtcggctatt gtgtaaagcc atatagctca gacgatgaat atctactcgt
      181 attcagttgt ttattgaggg tgagttccga ccctgaaaca acaaataaaa tgaacagtca
      241 gagagtttac atagaattgc actggtcttt tacgatatct gacattgtgt aatacatatt
      301 cagccatgca ttaattaaaa tgttacgtgt ttaatgtgag tccctatctg aaaataaata
      361 atccttccgg attaaaataa attcttgccg ggaaagaaag aggaaataaa ccattagcgg
      421 aaaaccagcg gcacgccagg gtgacatgcc ccagttcggc ggcccgatag tccagggttc
      481 agcgggggta ctgatagtcg cgccgactgc atcgagaact ccatacaact ttttacggaa
      541 cgtcacctga taaaatttgt tcagtatcgt cttttgagat tctcaaggtt atggagtaac
      601 cagacagaac ggacaccact gtcggagata aaaaccccct gtttacgcag ctcgttgctg
      661 gcccggtgct gaccatgtgt cgggaaagcg acggcgtaat caacaacagc ctgttcagtt
      721 gcctcatcgg tacggttctt aaggttagga gcgcggcgac tacgattaat ctgcgcatcc
      781 acaccgcctt cagcgaccag ttcgcggtaa cgataaaacg tatcacgcga aacgcccatg
      841 attttacagg cttttgatac gttgctgagt tcttcagcca gattgagcaa accggctttg
      901 tgtttgatga cgggattggc agtatgaagc atgagagtta cctcttgttt tggataagga
      961 ttcgacactc atatcaaaac cggtaactct caacctttca aggccatgtg tcagatcaag
     1021 tcgcgactaa tacaaatacg tccctcatta ccgcgcctta acccattccg ccacttccgc
     1081 ccactcaccg cgaaagacaa ctttttccgc ttttttctca agctgatagc gatacatcgg
     1141 gtcgtaatat tcttcaagta acggcaccag ccaggccaga tgaccgtcgg tgctgccggt
     1201 ggtgagttgc gttgtcagtg ctgcatccag ccttgcagcc agttcgttat agcgctgtag
     1261 ccccagccga cgcttaatcg ccgaaagtcc gtgatgcagg tattcgcaat actcctgcca
     1321 gccctgttcg tcgccgtacg cgtgggtaaa atcatgatgc atacgcaaga aatactcttc
     1381 gttcaggcgc tcaagacgga tctcaaacgg atcttctacc accgcaatcg ccgcctgagt
     1441 cattcgctcg cgcaggcatt ccggcaggtg attcgaaccg atcatccggc tttcgtcttc
     1501 cagcacccac aggcgcaaat tctgacgggc gtcggttttt agcatttcgg cagccagcag
     1561 gttttcaaaa ctcgcctggc taagttgtgg ttgtaacgtg cgaccaaacg ccgaaccgcg
     1621 atgacgcgcc aacccttcca gatcaacacc gttcggctgt tgctgcacta acagcgtttt
     1681 accgctgccg gtacaaccgc caatcagcac tatcggtttt tgtgccagtt caatagtcgc
     1741 ctgaatcgcg gtctggcgca gtgccttata accgccttcc accagcggat aatcaatccc
     1801 cgctgcatgc aaccagcttt gcacaatatg tgagcgctga ccgccacggg cgcagcagag
     1861 aataccttgc ggattttgca ggcacgctgc ccgccaggcg tccatgcgct gctgacgaat
     1921 ttcacccgcc accagtttat gtcccagcgc cagcgctgcg tctgagcctt gctgtttata
     1981 gcaggtgcca acggcggcgc gttcatcgtt attcattaac ggcagattga tagcggcggg
     2041 cattgcgccg tgctcaaact cgataggggc gcgaacatca ataatgggcg tatcagcaat
     2101 cagcagggca cgatagtcct gttccgtgtg tctctcttgc atagttaaaa gtgaacctca
     2161 aatcagcttg cgcgctattt tacgcgccaa cgcgcaagga aacttgattt ttaactgcgt
     2221 gggttgccga aaatttctaa aaatccgctg atttccggcc tgcgctgggt aaacaaggtc
     2281 acaatatctt ctaccgcttt gccgctgcca aatttgcgcc atgccagact caatggcgaa
     2341 ggagggcgca tcgttgggat tacccggctg accagttgtt gattatcgat cattgactgg
     2401 caaagcgatt ttggcaaaaa accaatgcca acgcccgcca gatgggcggc gattttcgtt
     2461 tccatatcgg gaacaataat ctctttttgc cctggcaatc gccaggcgac gcgtttggtt
     2521 aaggtacggg cgctgtcttc aatattgacc gccggaaagc gccgcaactg cgcttctgtt
     2581 agcggctctt caacgttcgc cagcggatga tccgccgcca tgacaaagcg ccattgcacc
     2641 gatcctaagg gatcaagact aaaggtattt gccagcgcct cagttcccgt gacgccgata
     2701 gccagcgaaa aaccttcgta caatagcgag tcccagacgc ccatatagat ttgtcgggag
     2761 atgtgaaact gggtaaaggg gtaacgctca ttcagccacg ccagcaactg ggcgacggcc
     2821 tgggggttgt agagcaggtt gttgatgaca atattcacct ggcgttccac gccatcattc
     2881 acctgttgca gctcgcttgg catactttcc agccagctca gccagtctct ggcctgggaa
     2941 agtagatgct cgccagccgc tgtcaacgtc acgctgcgag tcgtacggaa aaacagcgct
     3001 actccggtat tctcttccag aagtttaatg cgataactga tcgtcgccgt ggttttacat
     3061 aatcgttctg ccgcttttga aaaacttcct gtttcagcaa ccgcaatgaa agtccgcaag
     3121 gtttctggat cgaacatctt caggtatccc cttttaaatc cgcaagttgc gtgattttct
     3181 tatcctctga tttatcagta tttttacatg ataaccctgt tcaatttgtg gactaaatct
     3241 agttttggaa aaatattcca acttttgtat tgatgttgtt ctcttaaggt tttagattgc
     3301 ctgttattga aaccaagctg accggtcggc ggtggttgaa cggaattatg ttacaaggac
     3361 aaaaagatga aacttcaggt attaccgtta agtcaggaag cctttagtgc ttatggcgac
     3421 gtaatcgaaa cgcagcaacg ggattttttc catattaaca atggcctggt ggagcgttac
     3481 cacgatttgg cgctggttga gattcttgag caagaccgta cgcttatcag ca
//
LOCUS       DAPHKZ010000234         3483 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.239, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000234 DAPHKZ010000000
VERSION     DAPHKZ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3483
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.239"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..127)
                     /locus_tag="RH288_004555"
     CDS             complement(<1..127)
                     /locus_tag="RH288_004555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 family protein"
                     /protein_id="HDV4033515.1"
                     /translation="MDQVVIFKQIFDKVRNDLNYQWFYSELKRHNVSHYIYYLATE"
     gene            complement(185..418)
                     /locus_tag="RH288_004556"
     CDS             complement(185..418)
                     /locus_tag="RH288_004556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HDV4033516.1"
                     /translation="MSTKNRTRRTTTRNIRFPNQMIEQINIALEQKGSGNFSAWVIEA
                     CRRRLCSEKRVSSEANKEKSDITELLRKQVRPD"
     gene            807..1352
                     /locus_tag="RH288_004557"
     CDS             807..1352
                     /locus_tag="RH288_004557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HDV4033517.1"
                     /translation="MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSA
                     AVIRWYAERDAEIENEKLRREVEELRQASETDLQPGTIEYERHRLTRAQADAQELKNA
                     RDSAEVVETAFCTFVLSRIAGEIASILDGIPLSVQRRFPELENRHVDFLKRDIIKAMN
                     KAAALDELIPGLLSEYIEQSG"
     gene            1327..3252
                     /locus_tag="RH288_004558"
     CDS             1327..3252
                     /locus_tag="RH288_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HDV4033518.1"
                     /translation="MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADANYYLPKES
                     AYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTL
                     IWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFSNGRGFWCLG
                     GKAAKNYREKSVDVAGYDELAAFDEDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVR
                     GTCQIERAASESPHFMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEH
                     NACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFT
                     TWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDR
                     VAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYT
                     RRNGAEMSISRICWDTGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNK
                     NGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQV
                     EKWVDGRKKIRWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAAT
                     NKKTLADYARALSGEDE"
     gene            3249..3455
                     /locus_tag="RH288_004559"
     CDS             3249..3455
                     /locus_tag="RH288_004559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gpW family protein"
                     /protein_id="HDV4033519.1"
                     /translation="MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTATSVSDLK
                     KYIAELEVQTGMTQRRRGPAGFYV"
BASE COUNT          856 a          808 c          974 g          845 t
ORIGIN      
        1 tctctgtggc taaatagtaa atgtaatgtg agacattgtg acgttttagc tcagaataaa
       61 accattgata gtttaaatcg tttcgaactt tatcaaatat ttgtttaaaa atgactacct
      121 gatccataga taaaccttcc atgtgatatg agggggcgta gtctgcacga ttatctaaat
      181 tgcttcaatc tggtctgacc tgttttctga gcaattcagt aatgtcactc ttttctttgt
      241 ttgcttcaga agaaactctt ttttctgagc acagtctccg gcggcaggct tcaatgaccc
      301 aggctgagaa attcccggac cctttttgct caagagcgat gttaatttgt tcaatcattt
      361 ggttaggaaa gcggatgttg cgggttgttg ttctgcgggt tctgttcttc gttgacatga
      421 ggttgccccg tattcagtgt cgctgatttg tattgtctga agttgttttt acgttaagtt
      481 gatgcagatc aattaatacg atacctgcgt cataattgat tatttgacgt ggtttgatgg
      541 cctccacgca cgttgtgata tgtagatgat aatcattatc actttacggg tcctttccgg
      601 tgatccgaca ggttacgggg cggcgacctc gcgggttttc gctatttatg aaaattttcc
      661 ggtttaaggt gtttccgttc ttcttcgtcg taacttaatg tttttattta aaataccccc
      721 tgaaaagaaa ggaaacgaca ggtgctgaaa acgggctttt tggcctctgt cgtttccttt
      781 ctctgttttt gtccgtggaa tgaacaatgg aagtcaacaa aaagcagctg gctgacattt
      841 tcggtgcgag tatccgtacc attcagaact ggcaggaaca gggaatgccc gttctgcgag
      901 gcggtggcaa gggtaatgag gtgctttatg actctgccgc cgttataaga tggtatgccg
      961 aaagggatgc tgaaattgag aacgaaaagc tgcgccggga agttgaagaa ctgcggcagg
     1021 ccagcgagac agatctccag ccagggacta ttgagtacga acgccatcga cttacgcgtg
     1081 cgcaggccga cgcacaggaa ctgaaaaatg ccagagactc cgctgaagtg gtggaaaccg
     1141 cattctgtac tttcgtgctg tcgcggatcg caggtgaaat tgccagtatt ctcgacggga
     1201 tccccctgtc ggtgcagcgg cgttttccgg aactggaaaa ccgacatgtt gatttcctga
     1261 aacgggatat catcaaagcc atgaacaaag cagccgcgct ggatgaactg ataccggggt
     1321 tgctgagtga atatatcgaa cagtcaggtt aacaggctgc ggcattttgt ccgcgccggg
     1381 cttcgctcac tgttcaggcc ggagccacag accgccgttg aatgggcgga tgctaattac
     1441 tatctcccga aagaatccgc ataccaggaa gggcgctggg aaacactgcc ctttcagcgg
     1501 gccatcatga atgcgatggg cagcgactac atccgtgagg tgaatgtggt gaagtctgcc
     1561 cgtgtcggtt attccaaaat gctgctgggt gtttatgcct actttataga gcataagcag
     1621 cgcaacacac ttatctggtt gccgacggat ggtgatgccg agaactttat gaaaacccac
     1681 gttgagccga ccatccgcga tattccgtcg ctgctggcgc tggctccgtg gtatggcaaa
     1741 aagcaccggg ataacacgct cactatgaag cgtttttcca atggtcgtgg cttctggtgc
     1801 ctgggcggta aagcggcaaa aaactaccgt gaaaagtcgg tggatgtggc gggttatgat
     1861 gaacttgctg cctttgatga ggatattgaa caggaaggct ctccgacgtt ccttggcgac
     1921 aaacgtattg aaggctcggt ctggccaaag tccatccgtg gctccacgcc caaagtgaga
     1981 ggcacctgcc agattgagcg tgcagccagt gaatccccgc attttatgcg ttttcatgtt
     2041 gcctgcccgc actgcgggga ggagcagtat cttaaatttg gcgacaaaga gacgccgttt
     2101 ggcctcaaat ggacgccgga tgacccctcc agcgtgtttt atctctgcga gcataatgcc
     2161 tgcgtcatcc gccagcagga gctggacttt actgatgccc gttatatctg cgaaaagacc
     2221 gggatctgga cccgtgatgg cattctctgg ttttcgtcat ccggtgaaga gattgagccg
     2281 ccggacagtg tgacctttca catctggaca gcgtacagcc cgttcaccac ctgggtgcag
     2341 attgtcaaag actggatgaa aacgaaaggg gatacgggaa aacgtaaaac cttcgtgaac
     2401 accacgctcg gtgagacgtg ggaggcgaaa attggcgaac gtccggatgc tgaggtgatg
     2461 gcagagcgga aagagcatta ttcagcgccc gttcctgacc gtgtggctta cctgaccgcc
     2521 ggtatcgact cccagctgga tcgctacgaa atgcgcgtat ggggatgggg gccgggtgag
     2581 gaaagctggc tgattgatcg gcagattatt atgggccgcc acgacgatga acagacgctg
     2641 ctgcgtgtgg atgaggccat caataaaacc tatacccgcc ggaatggtgc agaaatgtcg
     2701 atatcccgta tctgctggga tactggcggg attgacccga ccattgtgta tgaacgctcg
     2761 aaaaagcatg ggctgttccg ggtgatcccc attaaagggg catccgtcta cggaaagcca
     2821 gtggccagca tgcctcgtaa gcgaaacaaa aacggggttt accttaccga aatcggtacg
     2881 gataccgcga aagagcagat ttataaccgc ttcacactga cgccggaagg ggatgaaccg
     2941 cttcccggtg ccgttcactt cccgaataac ccggatattt ttgatctgac cgaagcgcag
     3001 cagctgactg ctgaagagca ggtcgaaaaa tgggtggatg gcaggaaaaa aatacggtgg
     3061 gacagcaaaa agcgacgcaa tgaggcgctc gactgcttcg tttatgcgct ggcggcgctg
     3121 cgcatcagta tttcccgctg gcagctggat ctcagtgcac tgctggcgag cctgcaggaa
     3181 gaggatggtg cagcaaccaa caagaaaaca ctggcagatt acgcccgtgc cttatccgga
     3241 gaggatgaat gacgcgacag gaagaacttg ccgctgcccg tgcggcactg catgacctga
     3301 tgacaggaaa acgggtggca acggtacaga aagacggacg gagagtggag tttacggcca
     3361 cttccgtgtc tgacctgaaa aaatacattg cggagctgga agtgcagacc ggcatgacac
     3421 agcgacgcag gggacctgca ggattttatg tatgaaaacg tccaccattc ccatccttct
     3481 ggg
//
LOCUS       DAPHKZ010000235         3348 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.240, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000235 DAPHKZ010000000
VERSION     DAPHKZ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3348
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.240"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            340..1656
                     /gene="shiA"
                     /locus_tag="RH288_004560"
     CDS             340..1656
                     /gene="shiA"
                     /locus_tag="RH288_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate transporter"
                     /protein_id="HDV4033520.1"
                     /translation="MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGIT
                     AALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVW
                     MMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKA
                     FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNG
                     MEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAYALNY
                     STQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGALIGTLSAFPFF
                     MALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVG
                     GGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDSQRA"
     gene            1758..3212
                     /gene="amn"
                     /locus_tag="RH288_004561"
     CDS             1758..3212
                     /gene="amn"
                     /locus_tag="RH288_004561"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HDV4033521.1"
                     /translation="MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDE
                     NARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLT
                     LLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
                     GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
BASE COUNT          764 a          830 c          810 g          944 t
ORIGIN      
        1 gtctcaacaa tgatgctaaa aacataccta acctcgcctc cctactggtt ataatgcatt
       61 gcagtctatc agactcatca tggcgcaatt ttgtgcatat gcggactttt atgtttcata
      121 tctcgaacct gtgggtcctc tgcttaatcc ttaaacaaca ccagcaactc ctgcgctttc
      181 atcttccagc gaatttttca tgttgccgtt aatcggccat aaaatcattt gcagatgcgc
      241 tctgtcgagg tagtctcata aggttcgttt atagatcgac ggcaatgtga gttacctttt
      301 ccatactaat tataaaaaga cagtacaaac aggatcatta tggactccac gctcatctcc
      361 actcgtcccg atgaagggac gctttcgtta agtcgcgccc gacgagctgc gttaggcagt
      421 ttcgctggtg ccgtcgtcga ctggtatgat tttttactct atggcattac cgccgcactg
      481 gtgtttaatc gcgagttttt cccgcaagta agcccggcga tgggaacgct cgccgcattt
      541 gccacctttg gcgtcggatt ccttttccgt ccgctcggcg gtgtcatttt cggtcacttt
      601 ggcgaccgac tgggacgtaa gcgcatgtta atgctgaccg tctggatgat gggcatcgcg
      661 acagccttga ttggtattct tccttccttc tcgaccattg ggtggtgggc acctatttta
      721 ctggtgacgc tgcgtgccat tcagggattt gccgtcggcg gcgaatgggg aggcgcggcg
      781 ttgctttccg ttgaaagtgc accgaaaaat aaaaaagcct tttacagtag cggtgtacaa
      841 gttggctacg gtgtaggttt actgctttca accggactgg tttcattgat cagtatgatg
      901 acgactgacg aacagttttt aagctggggc tggcgcattc ctttcctgtt tagcatcgta
      961 ctggtactgg gagcattgtg ggtgcgcaat ggcatggagg agtccgcgga atttgaacaa
     1021 cagcaacatt atcaagctgc cgcgaaaaaa cgcatcccgg ttatcgaagc gctgttacga
     1081 catcccggtg ctttcctgaa gattattgcg ctacgactgt gcgaattgct gacgatgtac
     1141 atcgttactg cctacgcact taattattca acccagaata tggggttacc gcgcgaactt
     1201 ttcctcaata ttggtttgct ggtaggtgga ttaagctgcc tgacaattcc ctgttttgcc
     1261 tggcttgccg atcgttttgg tcgccgcagg gtttatatca caggcgcgtt aatcggaacg
     1321 ttgagcgcat ttcctttctt tatggcgctt gaagcacaat ctattttctg gatagttttc
     1381 ttctccataa tgctggcaaa cattgcgcat gacatggtgg tgtgtgtgca acaaccgatg
     1441 tttaccgaaa tgtttggtgc cagttatcgc tatagtggcg ctggagtcgg ttatcaggtt
     1501 gccagtgtgg ttggcggtgg atttacacct tttattgccg ctgcactcat cacttacttt
     1561 gccgggaact ggcatagcgt cgccatttat ttgctggctg gatgcctgat ttccgcaatg
     1621 accgctttgt tgatgaaaga cagtcaacgc gcttgatagc ctggcgaaga tcatccgatc
     1681 ttcgccttac acttttgttt cacatttctg tgacatacta tcggatgtgc ggtaattgta
     1741 tggaacagga gacacacatg aataataagg gctccggtct gaccccagct caggcactgg
     1801 ataaactcga cgcgctgtat gagcaatctg tagtcgcatt acgcaacgcc attggcaact
     1861 atattacaag tggcgaatta cctgatgaaa acgcccgcaa acaaggtctt tttgtctatc
     1921 catcactgac cgtaacctgg gacggtagca caaccaatcc ccccaaaacg cgcgcatttg
     1981 gtcgctttac ccacgcaggc agctacacca ccacgattac tcgccctact ctctttcgtt
     2041 cgtatcttaa tgaacaactt acgttgctgt atcaggatta tggtgcgcat atctcagtgc
     2101 aaccctcgca gcatgaaatc ccttatcctt atgtcatcga tggctctgaa ttgacacttg
     2161 atcgctcaat gagcgctggg ttaactcgct acttcccgac aacagaactg gcgcaaattg
     2221 gcgatgaaac tgcagacggc atttatcatc caactgaatt ctccccgcta tcgcattttg
     2281 atgcgcgccg cgtcgatttt tccctcgcac ggttgcgcca ttataccggt acgccagttg
     2341 aacattttca gccgttcgtc ttgtttacca actacacacg ttatgtggat gaattcgttc
     2401 gttggggatg cagccagatc ctcgatcctg atagtcccta cattgccctt tcttgtgctg
     2461 gcgggaactg gatcaccgcc gaaaccgaag cgccagaaga agccatttcc gaccttgcat
     2521 ggaaaaaaca tcagatgcca gcatggcatt taattaccgc cgatggtcag ggtattactc
     2581 tggtgaatat tggcgtggga ccatccaatg ctaaaaccat ctgcgatcat ctggcagtgc
     2641 tacgcccgga tgtctggttg atgattggtc actgtggcgg attacgtgaa agtcaggcca
     2701 ttggcgatta tgtacttgca cacgcttatt tacgcgatga ccacgttctt gatgcggttc
     2761 tgccgcccga tattcctatt ccgagcattg ctgaagtgca acgtgcgctt tatgacgcca
     2821 ccaagctggt gagtggcagg cccggtgagg aagtcaaaca gcggctacgt acaggtactg
     2881 tggtaaccac agatgacagg aactgggaat tacgttactc agcttctgca cttcgtttta
     2941 acttaagccg ggccgtagca attgatatgg aaagtgcaac cattgccgcg caaggatatc
     3001 gtttccgcgt gccatacggg acactactgt gtgtttcaga taaaccgttg catggcgaga
     3061 ttaaacttcc cggtcaggct aaccgttttt atgaaggtgc tatttccgaa cacctgcaaa
     3121 ttggcattcg ggcgatcgat ttgctgcgcg cagaaggcga ccgactgcat tcgcgtaaat
     3181 tacgaacctt taatgagccg ccgttccgat aataagttct gaaccttctc atcagaaata
     3241 gatgtgaagg attaagtaag acatctggca aatagcctgc aatcaacgcg ggctgtttgc
     3301 ttccttgggc agatgcgagt ttcattatcg tcttaatgat ttccgcat
//
LOCUS       DAPHKZ010000236         3346 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.241, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000236 DAPHKZ010000000
VERSION     DAPHKZ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3346
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.241"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..2154)
                     /locus_tag="RH288_004562"
     CDS             complement(<1..2154)
                     /locus_tag="RH288_004562"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024418.1,HMM:NF027494.1,HMM:TIGR04415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HDV4033522.1"
                     /translation="MNKIYNIVWNESSGMWVVTSELTRKGGQRHRKIKRTMLAGLIAG
                     LMLPTVPALAQVFNDEILDYSSSMSLSAGDSAFNTTIDGGEQYVSSGGSAISTTINDG
                     AQIIFNGGTASTTTINGGYQDISSGGSVTNTLISGGEQNISSGGSAVDTTIEEGLQTV
                     LNGGNVSGTHISGGEQYISDGGSATNTVIDGGTQYISSGGNAIETTIENGFQEVSNGG
                     SATSTVINAGFQYISSGGSATSTIINAGFQDVSSGGSATSTTINGGFQLISSGGSAVD
                     TTIQGGIQIGEGGSASGTTINNSGIQFISSGGSATATTINSGGWQEISSGGSATETAI
                     NGGIQWIYDGGSASDSTINSGYQVISSGGSVTSTTIYRGGEQSIHNAGLATGTIISGG
                     EQLVSSGGSAVDTTIEGGLQTILNGGNVSGTLISGGVQRVSSGGSAVDTTVEEGLQTV
                     LNGGNVSGTLISGGEQNISSGGSAVDTTIEVGLQTVFDGGSVNGTIIDGGEQHISSGG
                     SAINTTLDGYQTVFNGGNATGTTINGGFQDISSGGSATSTVINAGFQTLYDNSIASGT
                     VINSGFQLISSGGSSVDTTIQGGIQEVGEGGSASATTINDGFQFISSGGNATSTTINS
                     GWQEISSGGSATETVINGGIQTIYDGGSASEITINSGYQVISSGGSVTTTTIYHGGEQ
                     SITNAGLATGSIIRGGEQRVSSGGSAVDTTIEGGLQ"
     gene            complement(2147..3340)
                     /locus_tag="RH288_004563"
     CDS             complement(2147..3340)
                     /locus_tag="RH288_004563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter strand-loop-strand
                     O-heptosyltransferase"
                     /protein_id="HDV4033523.1"
                     /translation="MTPPEKPTQSGPEGIRYDFNDGARVLLPEGKWHVRLMDADSGNI
                     LFSCDADNGWVRSCKKYFIRFRIQVFHRGNDTPLMDETLNLKNQPVLISFPTGTLGDL
                     LGWFPYAERFQTLHKCQLECTMAQEIIELLAPQYPQIQFSTPDNPHTITPYATYRVGL
                     YFGGDTTNQPIDFRQVGFHRSAGYILGVDPRESPVRLNLSAPRSINEPYVCIATQSTC
                     QAKYWNNGTGWSEVVAHLKSLGYRVLCIDLHAHYGQGFVWNHIPWGAEDFTGKIPLQE
                     RVNLLHHASFFIGLSSGLSWLAWATHIPVVLISGFTLPVSEFYTPWRIFSSHGCNGCW
                     DDTSLNFDHKDFLWCPRHKNTPRQFECTRLITGKQVNGVIDKLHASLAEQSSIGMNHS
                     RWSNE"
BASE COUNT          877 a          897 c          696 g          876 t
ORIGIN      
        1 ctgcagtccc ccctcaatgg tggtgtcaac ggcactgcca ccgctggaaa ctcgctgctc
       61 cccgccacga atgatggatc cggtcgcaag acctgcattg gtaatactct gctccccacc
      121 atggtaaatg gtcgtagtgg ttacactgcc gccgctggag atgacctgat agccactgtt
      181 gattgtgatc tccgaagctg agcctccatc gtaaatcgtc tggatacctc cgttaatgac
      241 cgtttcagtt gcagatccac cactggatat ttcctgccag ccactattga tagtggtact
      301 tgtggcattt cctccactgc tgatgaactg aaaaccatca tttatagtcg tagcacttgc
      361 acttcccccc tcaccaactt cctgaatccc accttgaata gtggtgtcaa cagaactgcc
      421 accactggaa atgagctgga agccactatt aataacggtg ccgcttgcaa tactgttatc
      481 gtagagagtc tggaatccgg cattaataac ggtgctggta gcactgccac cactggaaat
      541 atcctggaac ccgccattaa tagtggtgcc tgttgcgttg ccaccattga aaactgtctg
      601 atagccatcc agtgtagtgt taatcgcact tcccccactg gaaatgtgct gctccccacc
      661 atcaatgatc gtgccattaa cacttccgcc atcaaaaaca gtctgtagtc ccacctcaat
      721 ggtggtgtct acagcactac caccgctgga aatattctgc tcacctccgc taatgagtgt
      781 cccggagaca tttccgccat tgagaacagt ctgaagcccc tcctccacgg tggtgtctac
      841 agcactacca ccgctggaaa ctcgctgcac tcctccgcta atgagtgtcc ctgatacatt
      901 tccgccattg agaatggtct gcagcccccc ctcaatggtt gtatctacgg cactaccacc
      961 gctggagact agctgctccc cgccactgat gatggttccg gtcgcaagac ctgcattgtg
     1021 aatactctgc tccccaccac ggtaaattgt ggtagaagtt acactgccgc cgctggagat
     1081 gacctggtaa ccactgttga tggtactatc tgaagctgag cctccatcgt aaatccactg
     1141 aatgcctcca tttatggccg tctcagttgc agagccacca ctggatattt cctgccaacc
     1201 gccactatta atagtggttg ctgtagcact tcctccactg ctgatgaact ggataccaga
     1261 attatttata gtggtaccac ttgcacttcc cccctcacca atttgaatcc cgccttgaat
     1321 agtggtgtca acagcactgc caccgctgga aatgagctgg aagccaccat taatagtggt
     1381 gctggtagca ctgccaccac tggaaacatc ttggaatccg gcattaataa tggtgctggt
     1441 agcactacca ccacttgaaa tgtactggaa tccggcatta ataacggtac tagtagcact
     1501 gccaccattg gaaacctcct ggaacccatt ttcaatagtg gtttcaatag cattgcctcc
     1561 actggatata tattgagttc ccccatcgat aacggtatta gtcgcactgc caccatcgga
     1621 aatatactgt tctcctccgc taatgtgagt cccggagaca tttccgccat tgagaacagt
     1681 ctgaagcccc tcctcaatgg tggtgtccac ggcactgcca ccgctggaaa tgttctgctc
     1741 acctccgcta attagtgtat tagtgacact tccaccactc gaaatatctt ggtaaccacc
     1801 attaatggtt gtcgttgaag cggtaccacc attgaaaatt atctgtgccc catcattgat
     1861 agtcgtgctt atagcgctgc caccactgga tacgtattgc tctccgccat caatggtggt
     1921 attaaatgcg gaatcacctg ctgataaaga cattgagcta ctataatcaa gtatttcatc
     1981 attaaatact tgggcaagag caggtacggt tggcaacata agccccgcaa ttagtccggc
     2041 taacattgtt ctctttattt ttcgatgccg ttgcccacct ttgcgggtta gctcagaagt
     2101 caccacccac ataccagaag attcattcca tacaatatta tagattttat tcattactcc
     2161 accttgaatg attcatacca atactacttt gttctgccag agaggcatga agtttgtcga
     2221 tgacgccgtt tacctgcttc cccgtaatca ggcgtgtaca ttcaaattgt ctgggggtgt
     2281 ttttatgtct cggacaccac agaaaatctt tatgatcaaa attcagtgaa gtatcatccc
     2341 agcatccgtt acatccatgg gaactaaata ttctccatgg ggtataaaat tcactgacag
     2401 gaagcgtaaa accacttatt agtacaacag ggatatgagt tgcccatgcc agccaggaga
     2461 gcccgctgga taaaccaata aaaaaactgg catgatgtaa cagattcacc cgttcctgca
     2521 gaggtatttt ccctgtaaag tcttctgctc cccacggaat atggttccag acaaagccct
     2581 gaccataatg agcatgcaga tcaatacaca gtacccgata ccccagcgat ttgagatggg
     2641 ctacaacctc actccagcca gtaccgttgt tccagtattt cgcctgacaa gtggattgtg
     2701 tcgcgataca tacataaggc tcattaatgc ttctgggggc tgaaagatta agtcggactg
     2761 gtgattcccg gggatccact cccagaatgt atccagcgga acgatgaaaa ccgacctggc
     2821 gaaaatcaat tggctggtta gttgtatcgc caccaaaata cagtcctaca cgataagttg
     2881 catatggcgt aatcgtatga ggattatctg gagtagaaaa ttgaatctgc ggatattgcg
     2941 gtgccagtag ttcaataatc tcctgtgcca tagtgcattc cagttgacac ttatgcagcg
     3001 tctgaaacct ttcagcataa ggaaaccatc cgagtaaatc acctaatgta ccggtaggaa
     3061 acgaaatcag cacaggctga ttttttaaat tcaacgtttc atccattaag ggcgtgtcgt
     3121 ttcccctatg gaatacctga atacgaaaac gaatgaagta ttttttacag ctccttaccc
     3181 agccattatc tgcatcgcag ctaaaaagaa tgttccccga atcagcatcc atcagacgaa
     3241 catgccattt cccctcaggg agcagtacac gcgccccatc attaaaatca tatcggatac
     3301 cctcaggtcc ggactgagtc ggtttctctg gcggagtaat aaaata
//
LOCUS       DAPHKZ010000237         3304 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.242, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000237 DAPHKZ010000000
VERSION     DAPHKZ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3304
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.242"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(127..1086)
                     /gene="rfaC"
                     /locus_tag="RH288_004564"
     CDS             complement(127..1086)
                     /gene="rfaC"
                     /locus_tag="RH288_004564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HDV4033524.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQI
                     PSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAAL
                     VTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
                     GDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWG
                     APHEEERAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TVYGPTDPGLIGGYGKNQMVCRAPRENLINLNSQAVLEKLSSL"
     gene            complement(1090..2136)
                     /gene="rfaF"
                     /locus_tag="RH288_004565"
     CDS             complement(1090..2136)
                     /gene="rfaF"
                     /locus_tag="RH288_004565"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HDV4033525.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKRYDRAYVLPNSFKSALVPFFAGI
                     PHRTGWRGEMRYGLLNDVRVLDKEAWPLMVERYIALAYDKGIMRTAQDLPQPLLWPQL
                     QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVL
                     FGSAKDHEAGNEILAALNTEQQAWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVA
                     AALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAAEGYHQSLIDITPQR
                     VLEELNALLLQEEA"
     gene            complement(2146..3078)
                     /gene="rfaD"
                     /locus_tag="RH288_004566"
     CDS             complement(2146..3078)
                     /gene="rfaD"
                     /locus_tag="RH288_004566"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HDV4033526.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     DVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFT
                     QADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA"
BASE COUNT          804 a          866 c          792 g          842 t
ORIGIN      
        1 atcgacgaat gcaattatca ttgaaaaaaa acataatata taagttatta tctctaaaat
       61 cattgatgat ttcagagtgt aaggtttcaa tgaatgaagt ttaaaggatg ttagcatgtt
      121 ttacctttat aatgatgata acttttccaa aactgcttga ctgttgaggt taattaaatt
      181 ttctcttgga gccctacata ccatctgatt cttcccatac ccaccaatta atcccggatc
      241 ggttggtcca taaaccgtga tattgggtct atccagtgcc gccgttaaat ggcttaaccc
      301 cgtatccacc gacactacaa atttagcccc ggccagcacg cgggcaacgc cttccagact
      361 catcttcggc aatacttcaa cataagcaaa tccttccgcc agtcgtttcg cccgttcttc
      421 ctcatgcggc gcgccccacg gaagtttaat ccgtattcct gaatcagcca gtaaaccaat
      481 caattctcgc cagtgttctt ccggccagtg tttatcatca cgggtcgtcg catgaagaaa
      541 tacggcatat tcgccagcat ctgtaggcag gttcgtcaga aaatgctgtg cgatagcata
      601 atcgccctgg gtttgcggtt tgctatagcc caaacttttg gcaaacagtt cgcgggtgcg
      661 ttctacggcg tgctgctgtt ttgcaatatg atgcttacga ttgtaaaaca ggctggctaa
      721 aggttcgcga gcggtttgcc agtccatgcc atgctttacg ccatgcgcca gacgcgtcac
      781 cagcgccgcg ctttttacca gcccctgagc gtcgataact gcgtcatagt tctctgcttg
      841 tagcgcttca cgaaacgctt tgcgttccgc ttttatgggg gccgagaacc aggctttacg
      901 ccagcgacgt attgccacag gaataactcg ctcaacggca gcgtgccagg aaggaatctg
      961 tgcgaaccct tcttccacca cccagtcaaa cttaatccct gggattgcct gctgggcatc
     1021 agtgagtgcg ggcaacgtat ggagaacatc gcccatcgac gatgttttaa cgatcaaaac
     1081 ccgcatccgt caggcttcct cttgtaacaa tagcgcgttg agttcttcca gtacgcgctg
     1141 gggagtaatg tcgattaagc tctggtgata accctccgca gcgtcacctt tacgcacttt
     1201 gtgatagccg gtaatcaaac ggatcacgcg cgctttatgg gatagcggcg gtgtgaagtc
     1261 cgggctactc ggaccataca gggcaaccag cggacgattg agcgccgccg caacatgcat
     1321 caggccagaa tcgttagtga caatggcttt acaggctgca atcaggataa ccgcttgatc
     1381 aagctgtgtt tcccccgcca ggttccgaca ccatgcctgc tgctcggtat tcaaagcggc
     1441 aagaatctca ttgcccgctt catgatcttt cgccgagcca aacagaacca cctgataacc
     1501 ttcatcaatc agctgctttg ccagctccgc atagtggtag tgtggccagc gttttgccgg
     1561 accaaactcc gcacccgggc aaaaaccaat catcggacgt tctgatgaaa gcgaaaattg
     1621 attacaggta tatgattttt caccttcgct cacctgcaac tgcggccata acaatggctg
     1681 cggcagatct tgtgctgtgc gcataatgcc tttgtcatag gccagcgcta tatagcgttc
     1741 caccattagc ggccaggctt ctttatcgag cacgcgtaca tcgttgagta aaccgtagcg
     1801 catctcgccg cgccagccgg tgcgatgagg aatacccgcg aagaaaggca ctaatgcaga
     1861 tttgaaggag ttgggtaaga cgtaggcgcg gtcgtagcgc ttttcacgca ggctatgacc
     1921 cagtttgcgg cgttcgccga tttccagcgc tccgtgaccg agaggcatag gaatagcttc
     1981 gttaacttcc ggcatccgcg ataataatgg acggcaccat gccggtgcca tcacatcgat
     2041 tatcgcctgg ggatagcgcg cctggagcgt gcgatagaga ctttgcgaca tcatcatgtc
     2101 gccaacccaa gacgggccga tcaccagtat tttcatgcag agctcttatg cgtcgcgatt
     2161 cagccaggcc atgtattccg ttacaccttc agcaacggtt ttgaacggtt tgtcgtaacc
     2221 cgccgcgcgc agatttgtca gatctgcctg agtgaacgcc tgatagcggc ctttcagttt
     2281 atccgggaac ggaatgtatt cgatctggcc tttcttgtga taagccagcg tagcatcagc
     2341 taccgcctgg aaggattccg cacgaccagt accgagattg aagatgccgg aaacgccatt
     2401 ttccaggaac cacagattca catcagccac gtcgcccaca tagacgaagt cgcgtttgaa
     2461 gttctcgcta ccttcaaaca gcttcggtga ttcaccgttg ttaagctggg tgttgagatg
     2521 gaaagcgacg ctcgccatgc tgcctttatg gccttcacgc ggtccataaa cgttgaaata
     2581 acggaagcca acaatctgcg agttcgcttc aggcaggatt tgacgaacat attcatcaaa
     2641 caggaatttt gagtaaccgt agacgttcaa cggtttttcg tactcgcggg attcaataaa
     2701 gtcggaggtg cgtccgccgt aggtggctgc ggaagaagcg tacaggaacg ggatttcacg
     2761 ctccaggcag tagtgcagca gctccttgga gtattgatag ttgttatcca tcatatactt
     2821 gccgtcccac tcggtggtgg aagagcacgc gccttcgtgg aaaatcgctt cgacatcgcc
     2881 gaactcttcg ccagccataa tctggatcag gaagtcttcc ttatccatat agtctgcgat
     2941 attcagatcc accaggttca caaacttggt gccgtctttc aggttgtcca ccaccagaat
     3001 atcggtgatg cctttatcat tcagggcttt aacgatgttg ctgccgataa agcccgcgcc
     3061 gccggtaacg atgatcataa ctgtaacctt cgaattatgg agtcagagac aatctcagac
     3121 acgaatgtct gtaatcatac catcacatcc gaatcccttc agccctttac atagaggtgc
     3181 aaggatgcta attgcaacaa actagtttgg gttttagcta gtccttcatg gcggatgttg
     3241 gttttgcatg tgaatagtgc tttagtatca atattccgat gtatgataaa taacggaagc
     3301 attt
//
LOCUS       DAPHKZ010000238         3187 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.243, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000238 DAPHKZ010000000
VERSION     DAPHKZ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3187
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.243"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            148..1830
                     /locus_tag="RH288_004567"
     CDS             148..1830
                     /locus_tag="RH288_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310130.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HDV4033527.1"
                     /translation="MKSALKKSVVSTSISLILASGMAAFAAHAADDVKLKATKTNVAF
                     SDFTPTEYSTQGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAI
                     EAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGI
                     PLTETFLPELFQNHGYYTAAVGKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQ
                     NRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPF
                     MLYLAYNAPHLPNDNPAPEQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQ
                     YDNTIILFTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKL
                     ISAMDFYPTALDAADISIPKDLKLDGVSLLPWLQDKKQGEPHKNLTWITSYSHWFDEE
                     NIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTD
                     LQQKDNLAAANPQVVKEMQGVVREFIDSSQPPLSEVNQEKFNNIKKALSEAK"
     gene            1882..3039
                     /locus_tag="RH288_004568"
     CDS             1882..3039
                     /locus_tag="RH288_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HDV4033528.1"
                     /translation="MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIK
                     QYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEW
                     CAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFNTLTVI
                     NNVNVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAY
                     GKFMSTIFMQWVKNDVGKIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIY
                     ECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRISAKCLKCAYKPICNGGCPKHRIT
                     KVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN"
     gene            complement(3005..3127)
                     /locus_tag="RH288_004569"
     CDS             complement(3005..3127)
                     /locus_tag="RH288_004569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033529.1"
                     /translation="MTKHPTGIYVGCLVKVIRRRLRMELKESVINYSPFVLQHP"
BASE COUNT          970 a          687 c          637 g          893 t
ORIGIN      
        1 gaaagtaatg tcaacgcttt atggactgtt atttcccttt ctttagctaa atctgctatc
       61 tatttatgtg actaacttca cttacatcca cttatttctc ttcgtaaaat tactttggaa
      121 ttaagtacaa taagaagagg aacatttatg aagtctgcat taaagaaaag tgtcgtaagt
      181 acctcgatat ctttgatact ggcatctggt atggctgcat ttgctgctca tgcggcagat
      241 gatgtaaagc tgaaagcaac caaaacaaac gttgctttct cagactttac gccgactgaa
      301 tacagtaccc aaggaaagcc aaatattatc gtactaacca tggatgatct tggttatgga
      361 caacttcctt ttgataaggg atcttttgac ccaaaaacaa tggaaaatcg tgaagttgtc
      421 gatacctaca aaatagggat agataaagcc attgaagctg cacaaaaatc aacgccgacg
      481 ctcctttcat taatggatga aggcgtacgt tttactaacg gctatgtggc acacggtgtt
      541 tccggcccct cccgtgccgc aataatgacc ggtcgagcgc ccgcccgctt tggtgtctat
      601 tccaatactg atgctcagga tggtattccg ctaacagaaa ctttcttgcc tgaattattc
      661 cagaatcatg gttattacac tgcagcagta ggtaaatggc acttgtcaaa aatcagtaat
      721 gtgccggtac cggaagataa acaaacacgt gactatcatg acaacttcac cacattttct
      781 gcggaagaat ggcaaccgca aaaccgtggc tttgattact ttatgggatt ccacgctgca
      841 ggaacggcat attacaactc cccttcactg ttcaaaaatc gtgaacgcgt cccagcaaaa
      901 ggttatatca gcgatcagtt aaccgatgag gcaattggcg ttgttgatcg tgccaaaaca
      961 cttgaccagc cttttatgct ttacctggct tataatgctc cgcacctgcc aaatgataat
     1021 cctgcaccgg agcaatatca gaagcaattt aataccggta gtcaaacagc agataactac
     1081 tacgcttccg tttattctgt tgatcaaggt gtaaaacgca ttctcgaaca actgaagaaa
     1141 aacggacagt atgataatac tattattctc tttacctccg ataatggtgc ggttatcgat
     1201 ggtcctctgc cgctgaacgg ggcgcaaaaa ggctataaga gtcagaccta tcctggcggt
     1261 actcacaccc caatgtttat gtggtggaaa ggaaaacttc aacccggtaa ttatgacaag
     1321 ctgatttccg caatggattt ctacccgaca gctcttgatg cagccgatat cagcattcca
     1381 aaagacctta agctggatgg tgtttccttg ctgccctggt tgcaagataa gaaacaaggc
     1441 gagccacata aaaatctgac ctggataacc tcttattctc actggtttga cgaggaaaat
     1501 attccattct gggataatta ccacaaattt gttcgccatc agtcagacga ttacccgcat
     1561 aaccccaaca ctgaggactt aagccaattc tcttatacgg tgagaaataa cgattattcg
     1621 cttgtctata cagtagaaaa caatcagtta ggtctctaca aactgacgga tctacagcaa
     1681 aaagataacc ttgccgccgc caatccgcag gtcgttaaag agatgcaagg cgtggtaaga
     1741 gagtttatcg acagcagcca gccaccgctt agcgaagtaa atcaggagaa gtttaacaat
     1801 atcaagaaag cactaagcga agcgaaataa ctaaaccttc atgcggcgga attttccgcc
     1861 gccttattga gcgagatagc gatgcacgtt acagccaagc cctccagttt tcaatgtaat
     1921 ctcaaatgtg attactgttt ttaccttgaa aaagagtcgc agtttactca tgaaaaatgg
     1981 atggatgaca gcactctgaa agagttcatc aaacaatata tcgcagcgtc tggcaatcag
     2041 gtctatttta cctggcaagg cggtgaaccc actctggctg gcctggattt tttccgtaaa
     2101 gttattcact atcaacaacg ctatgcaggc caaaaacgta tttttaatgc attacaaacg
     2161 aatggcattt tattgaataa tgaatggtgt gcctttctca aagaacatga gtttctggtt
     2221 ggtatctcga tcgatggccc ccaggagcta catgaccgtt acagacgcag taattcaggc
     2281 aacggtactt ttgcaaaagt gatagcagcc atcgagcgtc tgaaatcata tcaagtagag
     2341 tttaatacgt taaccgtcat taataacgtt aatgtccatt accctcttga ggtttatcat
     2401 tttttaaaat ctatcggcag taaacatatg caatttatcg aattgctaga aaccgggacg
     2461 ccgaatattg atttcagtgg tcatagtgag aacacattcc gtatcattga tttttctgtg
     2521 cctcccacgg cttatggcaa gtttatgtca accattttta tgcaatgggt taaaaacgat
     2581 gtgggtaaaa ttttcatccg tcagtttgaa agctttgtca gccgtttttt ggggaatgga
     2641 cataccagtt gtattttcca ggagtcctgc aaggataatc tggttgttga aagtaatgga
     2701 gacatttacg aatgcgacca ttttgtctat ccacagtaca aaattggaaa cattaataaa
     2761 tctgaactca aaacgatgaa cagtgtacaa ctgacagcgc aaaaaaaacg gatttcagcg
     2821 aaatgtctga aatgtgcata taaacctatc tgcaatggcg gttgtcctaa gcatcgtatt
     2881 actaaagtaa acaatgagac tgtttcttat ttttgcgaag gttataaaat ccttttttca
     2941 accatggtac cttatatgaa cgccatggtg gagttagcta agaacagagt accgctttac
     3001 cacattatgg atgttgcaaa acaaatggag aataattaat aacgctctct tttaactcca
     3061 ttcttagcct ccttcttatg accttaacaa ggcacccgac ataaattcct gtcgggtgtt
     3121 tcgtcatcat catcttccct tacgaaaatc ctggcttacg tggtatgcgt cagggcatta
     3181 gcaatac
//
LOCUS       DAPHKZ010000239         3103 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.244, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000239 DAPHKZ010000000
VERSION     DAPHKZ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3103
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.244"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            94..>3103
                     /locus_tag="RH288_004570"
     CDS             94..>3103
                     /locus_tag="RH288_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HDV4033530.1"
                     /translation="MQRKTLLSACIALALSGQGWAADITEVETTTGEKKNTNVTCPAD
                     PGKLSPEELKRLPSECSPLVEQNLMPWLSTGAAALITALAVVELNDDDDHHHRNNSPL
                     PPTPPDDESDDTPVPPTPGGDEIIPDDPDDTPTPPKPVSFNNDVILDKTEKTLTIRDS
                     VFTYTENADGTISLQDSNGRKATINLWQIDEANNTVALEGVSADGATKWQYNHNGELV
                     ITGDNATVNNNGKTTVDGKDSTGTEINGNNGKVIQDGDLDVSGGGHGIDITGDSATVD
                     NKGTMTVTDPESMGIQIDGDKAIVNNEGESTITNGGTGTQINGDDATANNNGKTTVDG
                     KDSTGTEINGNNGKVIQDGDLDVSGGGHGIDITGDSATVDNKGTMTVTDPESIGIQID
                     GDQAIVNNEGESTITNGGTGTQINGNDATANNSGKTTVDGKDSTGTKIAGNIGIVNLD
                     GSLTVTGGAHGVENIGDNGTVNNKGDIVVSDTGSIGVLINGEGATVSNTGDVNVSNEA
                     TGFSITTNSGKVSLAGSMQVGDFSTGVDLNGNNNSVTLAAKDLKVVGQKATGINVSGD
                     ANTVNITGNVLVDKDKTADNAAEYFFDPSVGINVYGSDNNVTLDGKLTVVSDSEVTSR
                     QSNLFDGSAEKTSGLVVIGDGNTVNMNGGLELIGEKNALADGSQVTSLRTGYSYTSVI
                     VVSGESSVYLNGDTTISGEFPLGFAGVIRVQDKALLEIGSGATLTMQDIDSFEHHGTR
                     TPELTYADSGAKIVNKGTVEIQNLGFAFVTGENTTGINSGTISLLQNGKDPAPSPIVL
                     LATNGGSATNAGTITGKVTEQHSVFNKYSTGTSNSFIFNNDVSSITGLVAQSNSTIIN
                     TDSGIIDLYGRGSVGMLAIADSTAENQGKITLDSMWVDANDTTAMRDIASNSAIDFGT
                     GVGVGTDSYSGAGKNATAINQLGGVITIYNAGAGMAAYGASNTVINQGTINLEKNGNY
                     DDSLAANTLVGMAVYEHGTAINDQTGVININ"
BASE COUNT          913 a          649 c          810 g          731 t
ORIGIN      
        1 tactggcaat attggatgtc ttctatgttt taaataacta attggtcggg ttagtgcatc
       61 cggctttctt tatattcgcc agaaggattt attatgcaaa ggaaaactct attgtcggcc
      121 tgtattgcat tagctctgag tggtcagggt tgggcggcag atatcacaga ggtagaaacc
      181 accacaggtg aaaagaaaaa taccaatgtg acttgtccgg cagacccagg aaaactcagt
      241 ccggaagagc ttaaacgctt accctctgaa tgctctcctt tagtcgaaca aaacctgatg
      301 ccatggcttt ccacaggcgc tgctgcgtta atcacggcct tagccgtagt ggaactaaac
      361 gacgatgatg atcatcatca tcgcaacaat tctccactcc caccgacacc ccctgatgat
      421 gaatcagacg acactccagt tcccccaact cctggcggag atgagataat accggacgat
      481 ccggatgata cgcctacacc tcccaaaccg gtttcgttta ataatgacgt tattctcgat
      541 aaaacagaaa aaacgttaac tattcgcgat tcagttttta cttataccga gaatgctgac
      601 gggactatat ctctgcaaga tagcaatggt cgtaaggcaa cgattaatct ttggcagatt
      661 gatgaagcga ataacactgt tgcccttgaa ggggtgagcg cagatggcgc aacgaagtgg
      721 caatataatc acaacggtga gcttgttatt acgggtgata atgccacagt aaacaacaat
      781 ggcaaaacca ccgttgacgg taaagattcc accggtacgg aaatcaacgg taataacggg
      841 aaagtgattc aggacggcga tctggatgtc agcggcggcg gtcacggtat tgatatcacc
      901 ggtgacagcg cgacggtgga taacaagggc accatgaccg tcaccgatcc ggagtccatg
      961 ggtatccaga tcgacggtga caaggccatc gtcaataacg aaggcgagag caccatcacc
     1021 aacggtggca ccggcaccca gattaatggt gatgacgcca cggcaaacaa caacggcaaa
     1081 accaccgttg acggcaagga ttccaccggt acggaaatca acggtaataa cggaaaagtt
     1141 attcaggacg gcgatctgga tgtcagcggc ggcggtcacg gtattgatat caccggcgac
     1201 agcgcaacgg tggataacaa gggcaccatg accgtcaccg atccggagtc catcggtatc
     1261 cagattgacg gcgaccaggc catcgtcaat aacgaaggcg agagcactat caccaatggc
     1321 ggcaccggca ctcagatcaa cggtaacgac gccaccgcga ataacagtgg aaaaaccact
     1381 gttgatggaa aagattccac gggtaccaaa atcgcgggca atatcggcat tgtaaatctg
     1441 gatggtagcc tgactgttac aggcggtgcg catggtgttg agaacattgg tgacaacggc
     1501 acggttaaca acaaaggaga tattgttgtt tccgatactg gatcgattgg cgtgctcatc
     1561 aacggtgagg gggcaacagt atccaatacg ggtgatgtta acgttagcaa tgaagcgaca
     1621 gggttcagca tcacaaccaa cagtgggaag gtttcgctgg caggcagtat gcaggttggc
     1681 gatttctcga ccggggtaga tcttaatggc aacaataaca gcgtgacgct ggcggcaaaa
     1741 gatctaaaag tggtcgggca gaaagcgacg ggcataaacg tttctggcga tgcgaataca
     1801 gtgaatatca ctggtaacgt tctggttgat aaggataaaa ccgcagacaa tgcggcggaa
     1861 tatttcttcg atccatccgt gggtatcaac gtttacggca gtgataataa cgtgacgctg
     1921 gatggaaagt taactgttgt atcagacagt gaggttactt ctcgtcagag taatttattt
     1981 gatggcagcg cagagaaaac gtcaggtctg gttgtgattg gcgatggcaa taccgttaat
     2041 atgaatggtg gacttgaact gattggagag aaaaacgcgc ttgcagatgg gtcgcaggtt
     2101 acttccttgc gcacaggata tagttatacc agcgttattg tcgttagtgg tgagtcgtcg
     2161 gtatatctga atggagatac gacaatcagc ggagaattcc ctctggggtt tgccggggtt
     2221 attcgggtac aggataaagc tttgctggaa attggcagtg gcgctacgct aacaatgcag
     2281 gatattgaca gttttgaaca tcatgggaca agaaccccag aacttactta tgctgattcc
     2341 ggtgcgaaaa ttgttaataa aggtactgtt gaaattcaga atttaggttt tgcttttgtt
     2401 actggtgaaa atacaacagg tataaatagt ggcacgatct cgttattaca aaatggtaaa
     2461 gatccggcac cgtctcccat tgttttactg gctactaacg gagggagcgc cactaatgca
     2521 ggtacgatca caggtaaagt gacggaacaa catagcgtat ttaacaagta ttcaacgggc
     2581 acatcgaatt catttatttt taataacgat gtcagtagca taacagggtt agtcgctcaa
     2641 tcgaatagca caattatcaa tactgacagc ggcatcattg atttgtatgg tcgtggtagt
     2701 gtcggcatgc ttgctatagc agattcaaca gcagaaaatc agggtaaaat tacactggat
     2761 tctatgtggg tagatgcaaa tgacactacc gcaatgcgag atatagctag caacagcgcc
     2821 attgacttcg gtacaggtgt gggagttggt actgatagtt atagtggtgc agggaaaaat
     2881 gcaacagcaa ttaaccaatt gggcggtgtt ataactattt ataacgccgg cgcaggtatg
     2941 gcggcctatg gcgccagcaa tacagttatt aaccagggga cgattaacct cgaaaaaaat
     3001 ggtaattatg acgatagtct ggcagcaaat actctggtag ggatggctgt ttatgagcat
     3061 ggtactgcta tcaacgacca gacgggtgtt atcaatatca atg
//
LOCUS       DAPHKZ010000240         2915 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.245, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000240 DAPHKZ010000000
VERSION     DAPHKZ010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2915
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.245"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            419..799
                     /locus_tag="RH288_004571"
     CDS             419..799
                     /locus_tag="RH288_004571"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDV4033531.1"
                     /translation="MQKNVTPGRRKGCPNYPPEFKQQLVAASCEPGISISKLALENGI
                     NANLLFKWRQQWREGKLLLPSSESPQLLPVTLDADAEQPESLAEDPETLSISCEVTFR
                     HGTLRFNGNVSEKLLTLLIQELKR"
     gene            796..1143
                     /gene="tnpB"
                     /locus_tag="RH288_004572"
     CDS             796..1143
                     /gene="tnpB"
                     /locus_tag="RH288_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019104956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDV4033532.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTELKDDPMSGHVF
                     IFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTQAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            1193..2730
                     /locus_tag="RH288_004573"
                     /pseudo
     CDS             1193..2730
                     /locus_tag="RH288_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc8 family transposase"
BASE COUNT          695 a          781 c          792 g          647 t
ORIGIN      
        1 tacgtctgga ctgctatttc agttgttttc ggtacgcaac cttcccatac tggcactaat
       61 catggggctt tcatttgcat tatacggact gataagaaaa ttcattcact atgatgctat
      121 aacctcagtc acgcttgaaa cattctggtc attacctgtt tcacttatcc tttttatata
      181 taccgacccg gatgtaacca cgccctctga gatcccatgt attctgtaca ttatgactgc
      241 accagtcact gttatcccgt tggtgctgtt tgctgttgca ctgaatcata catcacttat
      301 cgtaaccggc cttgcccaat atatcggtaa gcgtacagcc tgaaccgtct ggtcagaatc
      361 tgacgaatta gacaaagtgg tgtccaccaa ataagtagtg ggaaccaaag tatcagatat
      421 gcagaaaaat gtgactcccg gcaggcgaaa aggctgccct aattatcctc ccgaatttaa
      481 acagcagctc gttgctgcct cctgtgaacc cgggatatcc atctcaaaac ttgctcttga
      541 aaatggcatt aacgccaatc tgttgttcaa atggcgacaa caatggcgcg agggaaagct
      601 gctattacct tcttcagaga gcccccagct acttcctgtg actctcgatg cagatgccga
      661 acagccagaa tcgctcgcag aggacccgga aaccctcagt atcagctgtg aggtaacgtt
      721 ccggcacggg acgctccgct tcaatggcaa tgtcagcgaa aagctcctga ctctgctgat
      781 acaggaactg aagcgatgat cccgttacct tccgggacca aaatttggct ggttgccggt
      841 atcaccgata tgagaaatgg cttcaacggc ctggctgcga aagtacaaac ggagctgaaa
      901 gacgatccca tgtccggcca tgttttcatt ttccggggcc gcagcggcag tcaggttaaa
      961 ctgctgtggt ccaccggtga cggactgtgc ctcctgacca aacggctgga gcgtgggcgc
     1021 ttcgcctggc cgtcagcccg tgatggcaaa gtgttcctta cgcaggcgca gctggcgatg
     1081 ctgctggaag gtatcgactg gcgacagcct aagcggctgc tgacctccct gaccatgctg
     1141 taaatctctt tatcctggtt gtcacagaat aagcccggta aaatacaggc ttatgaacga
     1201 catttcttct gacgacatct tcctgctgaa acagcgcctg gccgaacagg aagcgctgat
     1261 ccacgccctg caggaaaagc tgagcaaccg ggagcgcgaa atagaccatc tgcaggcgca
     1321 gttggataaa ctccgccgga tgaacttcgg cagtcgttcc gaaaaagtct cccgccgtat
     1381 cgcacaaatg gaagccgatc tgaaccggct tcagaaagag agcgatacgc tgactggtag
     1441 ggtgtatgac ccggcagtac agcgtccgtt gcgtcagacc cgcacccgta agccgttccc
     1501 tgaatcacta ccccgtgacg aaaagcgact gtagcctgcg gcgccgtgct gcccgaactg
     1561 cggcggttca ctgagctatc tgggcgagga taccgccgaa cagctggagt tgatgcgtag
     1621 cgccttccgg gttatccgga cggtacggga aaacatgcct gtactcagcg cgatgccatc
     1681 gtgcaggcac ctgcaccttc gcggcccatc gagcggggta tcgccggacc ggggctgctg
     1741 gcccgcgtgc tgacctcgaa gtatgcagag cacaccccgc tgtatcgcca gtcagaaata
     1801 tacggccggc aaggtgtgga gctgaggcgt tcactgctgt cgggctgggt ggatgcatgc
     1861 tgccggctgc tgtctccgct ggaagaggcg cttcatggct atgtcatgac tgacggcaaa
     1921 ctccatgcct atgatacccc ggtccaggta ctgctgccgg gtaataagaa gacgaagacc
     1981 gggcggttgt gggcgtatgt tcgtgatgac cgcaatgccg ggtcagcgtt ggcacctgca
     2041 gtgtggttcg cttacagccc ggacagaaaa ggcatccatc cgcagactca tcttgcttgc
     2101 ttcagcggtg tgctgcaagc ggatgcgtac gccgggttca acgagctgta tcgcaatggt
     2161 gggataacgg aagctgcctg ctgggctcat gcccgccgaa agatccacga tgtgcacgtc
     2221 cgcatcccgt cagcactgac ggaagaagcc ctggagcaga tcggtcagtt gtacgccata
     2281 gaggcggata taaggggaat gccggcagag cagcggcttg ctgaacgtca gcgaaaaacg
     2341 aaaccgctgt tgaaatccct ggaaagctgg ttgcgtgaaa agatgaagac cctgtcgcga
     2401 cactcagagt tggcgaaggc gttcgcgtac gcacttaacc agtggccggc actgacgtac
     2461 tatgcgaacg atggctgggt ggaaatcgac aacaacatcg ctgaaaatgc cctgcgggcg
     2521 gtcagtctgg atcgtaaaaa cttcctgttc ttcggctctg accatggtgg tgagcgggga
     2581 gcgctactgt acagcctgat cgggacgtgc aaactgaatg acgtggatcc agaaagctac
     2641 cttcgccatg tgcttggcgt catagcagac tggccggtca accgggtcag cgaactgctt
     2701 ccgtggcgca tagcactgcc agctgaataa cacatccccg tcaatacggc cctcgctgta
     2761 cgcttattac gcagcaagtg cacaataagc taacgagact gtggattatt gttcaataat
     2821 aaacaattta gacattagca cacttgcgtc caggcagttt tagtggtgtg tacattatgg
     2881 gtataagaat aagatatcct ttcaggaact gttta
//
LOCUS       DAPHKZ010000241         2909 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.246, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000241 DAPHKZ010000000
VERSION     DAPHKZ010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.246"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(10..1172)
                     /locus_tag="RH288_004574"
     CDS             complement(join(10..911,911..1172))
                     /locus_tag="RH288_004574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS3 family transposase"
                     /protein_id="HDV4033533.1"
                     /translation="MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYES
                     QLYNWRSKQQNQQTSSERELEMSTEIARLKRQLAERDEELAILPKGRDILREAPEMKY
                     VFIEKHQAEFSIKAMCRVLRVARSGWYTWCQRRTRISTRQQFRQHCDSVVLAAFTRSK
                     QRYGAPRLTDELRAQGYPFNVKTVAASLRRQGLRAKASRKFSPVSYRAHGLPVSENLL
                     EQDFYASGPNQKWAGDITYLRTDEGWLYLAVVIDLWSRAVIGWSMSPRMTAQLACDAL
                     QMALWRRKRPRNVIVHTDRGGQYCSADYQAQLKRHNLRGSMSAKGCCYDNACVESFFH
                     SLKVECIHGEHFISREIMRATVFNYIECDYNRWRRHSWCGGLSPEQFENKNLA"
     gene            1240..1581
                     /locus_tag="RH288_004575"
                     /pseudo
     CDS             1240..1581
                     /locus_tag="RH288_004575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309324.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
     gene            1578..2564
                     /locus_tag="RH288_004576"
     CDS             1578..2564
                     /locus_tag="RH288_004576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033534.1"
                     /translation="MIPDYLTFIRFQDKRNLIYIYAIGLILIGFYWKNAGFTFPSEDI
                     GVVSGILALVLYNFIFDLKAYWAYKCVTKNIDFSWFKKKQNHKIELFLTQPLVAGFLS
                     LIMLSAMSWGLYQLLPSLYALFLISLLGPLVIFLLFRMIRTSYVKQVAISVAKKVKYK
                     SLTRYVLLSVCISTVVNLLTISPLRNSDSFVTEGQWLTFKSIIALLILCGVVLAINLF
                     FLRFSKRYAFLGRLFLQEIDLFFSSENALSTFFAKPLWLRLFILLVIEVMWITLVSVL
                     ATLVEWRIWFEAYFLLCYVPCLIYYFFYCRFLWHNDFMMACDMYFRWGHFNK"
     gene            complement(2757..2893)
                     /locus_tag="RH288_004577"
     ncRNA           complement(2757..2893)
                     /ncRNA_class="other"
                     /locus_tag="RH288_004577"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
BASE COUNT          651 a          679 c          719 g          860 t
ORIGIN      
        1 gacacaggcc taagcgaggt tcttgttttc aaattgttcc ggactgaggc cgccacacca
       61 actgtgccgc cgccaccgat tgtaatcaca ttcgatataa ttaaacaccg ttgcccgcat
      121 tatttcccgg ctgataaagt gttctccatg gatacattcc actttcagcg aatgaaagaa
      181 gctttccacg caggcattat cgtagcagca accttttgcg ctcatacttc cacgcagatt
      241 atgccgcttc agttgcgcct gataatctgc tgaacagtac tggcctccac ggtccgtgtg
      301 aacgataacg ttccggggcc tcttacgccg ccacagcgcc atctgcaggg catcgcaggc
      361 cagttgcgcc gtcatgcgtg gcgacattga ccagccaata acggcacgtg accacaggtc
      421 aatgaccact gccagataca gccagccttc atctgtacgt aagtacgtga tgtctcctgc
      481 ccacttctgg ttcgggccac tggcgtaaaa atcctgctcc aacagatttt ctgacacagg
      541 caggccgtgt gcgcggtagc tgaccgggct gaacttccgg gaggcctttg ccctcagtcc
      601 ctgacggcgc aggcttgccg ccacggtttt tacgttaaag gggtaaccct gagcacgcag
      661 ttcatccgtc aggcgtgggg caccgtaacg ctgttttgac cgggtaaaag ccgcgaggac
      721 aacgctgtcg cagtgttggc ggaactgctg acgcgtgctt atccttgtcc gccgctgaca
      781 ccacgtatac cagccgctgc gggccacccg gagcacgcgg cacattgctt tgatgctgaa
      841 ctcagcctga tgtttttcaa taaagacata cttcatttca ggcgcttcgc gaagtatgtc
      901 gcggcctttt ggaggatagc cagctcttca tcccgttctg ccagctggcg tttgagacgt
      961 gcaatctcgg tagacatctc cagttcacgt tcagaagacg tctgctgatt ttgctgttta
     1021 ctgcgccagt tgtagagttg tgattcatac aggctgagtt cacgggctgc ggcagtaaca
     1081 ccgatgcgtt cagcaagctt cagggcttca ctgcgaaatt caggcgaatg ctgtttacgg
     1141 ggttttttac tggttgatac tgtttttgtc atgtgagtca cctctgactg agagtttact
     1201 cacttagccg cgtgtccact attgctgggt aagatcagtg cctggcacac gcgtttgatg
     1261 gaagacggcg ttcaggcaat gcgcgattat cttgccggac tggatatcgc ttcgccagag
     1321 catcaggttc tgatgaacgt aacagcaaaa agcgaggtcg ctccgtcaat tatcaaagaa
     1381 aatctctcat tacacttaac tcatacggtg aaatggactg aatctctcga tacatttctg
     1441 aatatgccaa ccccggtagc tttccttgaa ataagtaata agccctattt ggggaatatg
     1501 ttaaatgatt ttgctggcgt ggatcagcaa cgagttatgc attgtcgtaa agcatttagt
     1561 gatgcaaagg tattcaaatg attcctgatt atttaacttt tattcgcttt caggataaac
     1621 gaaatctgat atacatttat gctattggac ttattctgat aggcttttat tggaagaatg
     1681 cagggtttac ttttccatca gaggatattg gtgtagttag tgggattctg gctctggtgc
     1741 tgtataattt tatttttgat ctcaaggcgt actgggctta taaatgcgtc acgaagaata
     1801 tcgatttttc gtggtttaag aaaaagcaga accacaaaat agaattattt cttacacaac
     1861 ctctggtggc aggatttctg tcgttaatca tgttgagtgc aatgagttgg gggctatacc
     1921 agcttctacc ctcgttatat gcgctgttcc tgatttcgtt acttgggccg ttggtcatct
     1981 ttctgctgtt tcggatgatc cgcaccagtt atgtcaagca ggtcgctatt tcagtagcga
     2041 aaaaagtaaa atataaaagt ctgactcgct atgtgctgct ttcggtgtgc atctcaacgg
     2101 ttgttaacct gcttactatc agcccgttgc gtaacagtga ttcttttgtg acagaggggc
     2161 agtggttaac gtttaaatcg ataattgcat tgctcattct ttgtggcgta gtgttggcga
     2221 ttaatctgtt ttttctgcgc ttctccaagc ggtacgcttt tctgggcagg ctttttttgc
     2281 aggaaatcga tctgtttttc tccagtgaaa atgcgttgtc gacctttttt gccaagccgc
     2341 tttggcttcg gttattcata ttgctggtta ttgaagtgat gtggattacg ctggtgtcgg
     2401 tattggcaac gcttgtagaa tggcggattt ggtttgaagc ctatttttta ctctgctatg
     2461 taccgtgctt aatttactat tttttctatt gtcgattcct ctggcataac gattttatga
     2521 tggcatgtga catgtatttc cgttgggggc attttaataa gtgaggaagt gataggaagt
     2581 gaccagataa tacatatatg ttctgtactc tcttgcgcat tttgattgtt gactgagtaa
     2641 ccagacagtt gatgtgcacg atttcccctc gccctaacag acgtgggcgg gggcacccgg
     2701 tgtgtgcaat atacgaaaaa aaagcccgta ctttcgtacg agctcttctt taaatatggc
     2761 ggtgaggggg ggattgactc gcttcgctcg ccctgcgggc agcccgctca ctgcgttcac
     2821 ggtctgtcca actggctgtc gccagttgtc gaaccccggt cggggcttct catccccccg
     2881 gtgtgtgcaa tatacgaaaa aaaagcccg
//
LOCUS       DAPHKZ010000242         2866 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.247, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000242 DAPHKZ010000000
VERSION     DAPHKZ010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2866
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.247"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            7..483
                     /gene="agaB"
                     /locus_tag="RH288_004578"
     CDS             7..483
                     /gene="agaB"
                     /locus_tag="RH288_004578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HDV4033535.1"
                     /translation="MTSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDD
                     IQQKLMGITAETYGFGIRFFTIEKTINVIGKAAPHQKIFLICRTPQTVRKLVEGGIDL
                     KDVNVGNMHFSEGKKQISSKVYVDDQDLTDLRFIKQRGVNVFIQDVPGDQKEQIPD"
     gene            522..1324
                     /gene="agaC"
                     /locus_tag="RH288_004579"
                     /pseudo
     CDS             522..1324
                     /gene="agaC"
                     /locus_tag="RH288_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIC"
     gene            1314..2105
                     /gene="agaD"
                     /locus_tag="RH288_004580"
     CDS             1314..2105
                     /gene="agaD"
                     /locus_tag="RH288_004580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IID"
                     /protein_id="HDV4033536.1"
                     /translation="MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKK
                     IYKDDKPGLSAAMKDNLEFINTHPNLVGFQMGLLISMEEKGENRDTIKGLKVALFGPI
                     AGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
                     KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDNTHSVALQQDFFDK
                     VFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL"
     gene            2106..2861
                     /locus_tag="RH288_004581"
     CDS             2106..2861
                     /locus_tag="RH288_004581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HDV4033537.1"
                     /translation="MERGTASGGASLLKEFHPVQTLQQVENYTALSERASEYLLAVIR
                     SKPNAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETF
                     LQQHIVQPLGLREDQLISFRSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLN
                     EPGESLQPACHISQLDARTQQHEMLKTAGRPVTRGITLGLKDILNAREVLLLVTGEGK
                     QDATDRFLTAKVSTAIPASFLWLHSNFICLINT"
BASE COUNT          696 a          680 c          724 g          766 t
ORIGIN      
        1 tacacaatga ccagtccaaa tattctctta acccgtattg ataaccgtct ggttcacggt
       61 caggttggcg tgacctggac atccaccatc ggtgcaaatc tgctggtagt cgtggatgat
      121 gttgtcgcta acgatgatat tcaacagaaa ttaatgggta ttaccgcgga aacctacggc
      181 tttggcattc gtttctttac tatcgaaaaa accattaacg tcatcggcaa agctgcacca
      241 catcagaaga tcttcctgat ttgccgtacg ccacaaacgg tacgtaaatt ggtagaaggt
      301 ggtattgacc tgaaagatgt caacgtcggc aatatgcatt tctcggaagg gaaaaagcaa
      361 atcagcagta aagtttatgt cgatgaccag gatctcacgg acttacgttt tattaaacaa
      421 cgtggcgtga atgttttcat tcaggacgtc cctggcgatc aaaaagaaca aatccctgac
      481 taaatctaaa atcgccttaa tattggtttg aggtaataaa aatgcatgaa ataaccctac
      541 ttcagggatt atccctggcg gcgttagttt ttgttctggg gattgatttt tggctggaag
      601 ccttattttt attccgcccg ataatcgttt gtaccctaac tggcgctatt ctcggtgata
      661 ttcagactgg cttaattacc ggtggtctga cagagttggc tttcgccgga ttaacccctg
      721 caggtggtgt tcagccgccc aacccgatta tggcgggtct gatgaccacc gtcattgcat
      781 ggtctacggg cgttgatgcc aaaacagcaa ttggtcttgg cctgccgttt agtttgttaa
      841 tgcagtacgt cattctgttc ttctattccg ctttctcatt atttatgacc aaagccgata
      901 aatgcgcgaa agaggcggat acggcagcgt tttcccggct taactggaca acgatgctca
      961 tcgtcgcttc agcgtatgcg gtgattgctt tcctctgtac ttacctggca cagggggcga
     1021 tgcaggcgct ggtgaaagcg atgcccgcct ggctgaccca cggctttgaa gtggctggcg
     1081 gtattctgcc tgccgttggt tttggcttgc tgctgcgcgt aatgttcaaa gcgcaatata
     1141 tcccttacct gatcgccggt ttcctgtttg tttgctacat ccaggtcagc aacctgttgc
     1201 cggttgccgt actgggcgca ggctttgcgg tgtatgagtt ttcaatgcga aatcccggca
     1261 gcaagcgcaa ccgcagcccg ttgccagtaa aaatgaagaa gaggactaca gcaatgggat
     1321 ctgaaatcag taaaaaagat atcacccgtc tgggctttcg ttcgtcgctg ctgcaagcga
     1381 gctttaacta cgaaaggatg caggcgggcg gttttacctg ggcgatgttg ccgatcctga
     1441 aaaagattta taaggacgac aaaccgggct taagcgcggc gatgaaagat aacctcgaat
     1501 ttattaatac ccacccgaat ctggtcggat tccagatggg gttattaatt tcgatggaag
     1561 aaaaaggaga aaaccgcgac accattaaag gcctcaaagt ggcactgttt ggcccaatcg
     1621 ccgggattgg cgatgcgatt ttctggttta ctttgttgcc gattatggcg ggaatttgct
     1681 catcatttgc cagccaggga aacctgctgg ggccgattct atttttcgcc gtttacctgc
     1741 ttatcttttt cctgcgcgtc ggctggaccc acgtcggtta ttcagtcggc gtgaaggcga
     1801 tcgataaagt gcgagagaac tcgcagatga ttgcccgttc ggcaaccatc ctcgggatca
     1861 cggtaatcgg cgggctgatc gcttcgtatg tgcatattaa cgtggtgaca tcgtttgcca
     1921 tcgacaatac ccacagcgtt gcgctgcagc aggatttctt cgataaagtc ttcccgaaca
     1981 ttttaccgat ggcctacacc ctgctgatgt attacttcct gcgggtgaaa aaagcgcatc
     2041 cggtgctgtt aatcggcgtg acttttgtgc tctctattgt ttgttccgca ttcggcattt
     2101 tgtaaatgga acgaggcact gcgtctggtg gtgcctcttt acttaaggaa tttcatcctg
     2161 tgcaaaccct tcagcaagtt gaaaactata cggcgttaag tgaacgtgcc agcgaatatt
     2221 tattggccgt gatccgtagc aaaccgaatg ccgtgatttg cctggcgacc ggagccacgc
     2281 cattactgac gtatcattat ctggtagaaa aaatccacca gcagcaggtt gatgtcagcc
     2341 agctcacctt cgtgaagctc gacgaatggg tggatctgcc attaacgatg ccaggcacct
     2401 gcgaaacttt cctgcaacag catatcgtgc agccgctggg gctacgtgaa gaccagctca
     2461 tcagctttcg ctccgaagag ataaatgaga cagagtgcga acgggtaacg aacctgattg
     2521 cgcgcaaagg cggtctggat ttatgcgttc tcggattggg gaaaaacggt catcttgggc
     2581 tgaacgaacc gggagaaagc ctgcaaccgg cctgccatat cagtcaactt gatgccagaa
     2641 cacagcaaca tgagatgtta aaaaccgcgg gtcgccccgt gactcgtggg atcaccttag
     2701 gcctgaagga tattctcaat gcccgcgaag ttttgttact ggtgactggc gaaggaaagc
     2761 aggatgcgac agatcgtttt ctcacggcta aagtctctac cgctatcccg gcttcatttt
     2821 tatggctgca cagtaacttt atttgtttaa ttaacaccta accaga
//
LOCUS       DAPHKZ010000243         2839 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.248, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000243 DAPHKZ010000000
VERSION     DAPHKZ010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2839
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.248"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            72..704
                     /gene="comR"
                     /locus_tag="RH288_004582"
     CDS             72..704
                     /gene="comR"
                     /locus_tag="RH288_004582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415629.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HDV4033538.1"
                     /translation="MATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFA
                     AIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
                     IPPHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK"
     gene            complement(766..1305)
                     /locus_tag="RH288_004583"
     CDS             complement(766..1305)
                     /locus_tag="RH288_004583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HDV4033539.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
                     PGTQIPLDSNGQLILNNKV"
     gene            complement(1515..2819)
                     /gene="ndh"
                     /locus_tag="RH288_004584"
     CDS             complement(1515..2819)
                     /gene="ndh"
                     /locus_tag="RH288_004584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HDV4033540.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGE
                     RILPALPPRISAAAHNELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGI
                     KAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
BASE COUNT          675 a          781 c          704 g          679 t
ORIGIN      
        1 ctggactggt gaacggaggt gattattttt ataataacct ttcattcaca gtcaccaggt
       61 acaacggcat catggcaact gactcaacac aatgtgtaaa aaaaagccgt ggccgcccaa
      121 aagtgttcga cagggatgcc gcgcttgata aggccatgaa attgttctgg caacacggtt
      181 atgaagcgac ttctcttgcg gacctcgtcg aagcgaccgg agccaaagcg cccacgctat
      241 acgcggaatt taccaacaaa gaggggttat ttcgtgccgt tctcgaccgc tatatcgatc
      301 gttttgccgc taagcatgaa gcacagctgt tttgtgaaga gaaaagcgtg gagtctgcgc
      361 tggctgacta ttttgctgcc atcgccaact gctttaccag caaagacacc ccggcaggct
      421 gcttcatgat caacaactgc accaccctct ccccagattc aggagatatc gccaatacgt
      481 tgaaatcacg ccatgcgatg caagagcgca ctttgcagca gtttttatgt caacgacaag
      541 cgcgcgggga aatcccgccc cactgtgacg tgacacatct ggcagaattc cttaattgta
      601 ttattcaggg gatgtcgatc agcgcacgcg aaggtgcatc gctggaaaaa ctgatgcaga
      661 ttgccggaac gactttgcgt ttatggcccg aactggtgaa ataagtcgca aaaaaagccc
      721 ctcagcctga gcgaatgagg ggccaaattg cagagtacag ccttgttata ctttgttatt
      781 caaaatcagt tgcccgttgc tatctagcgg gatctgcgta cccggatcgc ggtccatgcg
      841 gattttgccc tgctgatcgc caatcttata ggtcacatca taaccgagca ttttttctga
      901 cttgtcatac accgttttac aacgctgttg cgtagtcgtg taagtatcgc tttcctggag
      961 agagccctgg atctggttac cggcatatcc accacccagc gcccccacaa cagtggcgac
     1021 atctttaccg cgaccaccac caaactgatg ccctatcacg ccgccagcaa cagcgccgag
     1081 caccgacccg gtaatgcgat tttcatcctg caccggtcga cgatgggtca ctgtgacgtt
     1141 gcgacactcc tgacgcggtg ttttaaccgt ttccttgatt ggggttgcag aaacaacctg
     1201 agcgtattgc gggccccgtt caaacacgtt cagactggcc actgccgcta cgcccagcgc
     1261 agctgcgaca ccaatcccga tacccgccaa cattgattta ttcacgggaa cacctccttc
     1321 tttgcagtta tgccaatcat gcaagcgaag gagaaaagca gctatcagac agaagatgaa
     1381 aagcgcggga atggctggaa atacttaagg attcggagga gtctgaaagg atgcctgata
     1441 caacgcggct gccgatcgcg ctgttcctca agggcggatg aggcgtttat gccacatccg
     1501 ccagtgtacg tcgattaatg caacttcaaa cgcggacgga taacgcggtt aatactcccc
     1561 accagcatca ttaatccggt tttaaagtaa ccatgcagcg caatctgatg cattcggtat
     1621 agcgagatat atacaaagcg cgcaattcgt ccttcaatca tcattgagcc gcgcgtcagg
     1681 ttacccatca ggctaccgac ggtggagaag ttcgacagcg ataccagcga accatgatct
     1741 ttatactgat aatttttcag cggcttaccg ttcatctgcg ccagaatgtt gttcattgcg
     1801 caagtcgcca tctggtgtgc agcctgagca cgcggcggaa caaagccccc ttccggacgc
     1861 gggcatgacg cgcagtcgcc aatagcgtaa atgtctggat cgcgggtggt ttgcagcgtc
     1921 ggttccacca ccagctggtt gatacggtta gtttcaagac caccgatatc tttcaggaag
     1981 tctggcgctt tgatcccggc tgcccatacc atcagatcag cctcaatata ttcgccatct
     2041 ttagtgtgca ggccgccttc atcagcactg gtgaccatgg tttgcgtcag cacgcgaacg
     2101 ccaagtttcg ttagctcgtt gtgggccgca gcagagatac gtggcggtaa cgcaggcaaa
     2161 atacgttctc ccgcttctac cagcgttacg ttcagggctt cgttggtcag gcctttgtaa
     2221 ccgtagctgt gcagttgctt gaccgcgttg tgcaattcag cggagagttc tacacccgtc
     2281 gcgccgccgc cgacaatcgc aatgttcact ttgccattcg cgcccaggtt ggcggagtat
     2341 ttcaggaaca aattcagcat ctcctggtgg aagcgacgcg cctggtgcgg gttatcgagg
     2401 aaaatgcagt tctctttgac acctggcgta ttgaaatcgt tagaggtgct acccagcgcc
     2461 attaccaggg tgtcataggc gattttacgt tccggaacca gcagttcacc tttctcgtcg
     2521 cgcagttctg caatagtgat tgttttcgct tcacgatcaa tatcaatgac ggaacccagc
     2581 tggaactgga aaccatgatt gcgcgcatgg gccagatagc tcaacgcatc gacgccttca
     2641 tcaagcgagc cagtcgccac ttcgtgcagc agcggtttcc acaggtggct gtggttacga
     2701 tcgaccagcg taattttggc ttttttcttg cgtcccagct tatgccccag ctgtgttgcc
     2761 atttccagcc caccagcacc gccgccgaca atcacaatct ttttcaatgg cgtagtcaac
     2821 gtgaccccct taaatttat
//
LOCUS       DAPHKZ010000244         2833 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.249, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000244 DAPHKZ010000000
VERSION     DAPHKZ010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2833
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.249"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            113..1060
                     /gene="ompP"
                     /locus_tag="RH288_004585"
     CDS             113..1060
                     /gene="ompP"
                     /locus_tag="RH288_004585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease OmpP"
                     /protein_id="HDV4033541.1"
                     /translation="MQTKLLAIMLAAPVVFSSQEASASDFFGPEKISTEINLGTLSGK
                     TKERVYEPEEGGRKVSQLNWKYSNAAILKGAVNWELNPWLSVGAAGWTTLNSRGGNMV
                     DQDWMDSGTPGTWTDESRHPDTRLNYANEFDLNVKGWFLKESDYRLAIMAGYQESRYS
                     FNATGGTYIYSENGGFRNETGALPDKIKVIGYKQHFKIPYVGLTGNYRYDNFEFGGAF
                     KYSGWVRGSDNDEHYVRQTTFRSKVKNQNYYSVAVNAGYYITPEAKVYIEGVWSRLTN
                     KKGDTSLYDRSDNTSEHNNNGAGIENYNFITTAGLKYTF"
     gene            1165..2652
                     /locus_tag="RH288_004586"
     CDS             1165..2652
                     /locus_tag="RH288_004586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV4033542.1"
                     /translation="MKPLRRTLVLFIFSVFLCGTVSARQIEWQSCMTSPYSDWFGTES
                     PSPELLCGYLSVPLKYTDTGGDMSDENIPLVRLAMTKLPAKSKRKGSIIIISGGPGLP
                     GINPYINFDWPVTNLRESWDIIGFDPRGVGQSFPAINCQQPNQERSVNVSEKQLILQK
                     INACIHNTGAEVIRHIGSHEAVYDIERIRQALGDKQLTAVAYSYGTQIAALYAERFPS
                     SIRSIVFDGVVDIDDLNDNFSWKLRQAHSYQETFDRFAAWCARTKSCPLSSDRNQAIH
                     QFHQLLLKLHNSPLTDSRGESISSDDLISLTTELLLWRSSWPTLATAVRQFSQGIVSN
                     EIETALNSSIASEKVSDALGVILCVDQSDEQLSQEQRKSRKKALADAFPAVNFEREQS
                     DLPEFCELWPIHRDLQQTRLKNTVLPSGLLFVAHKYDPTTPWINARKMADKFSAPLLT
                     INGDGHTLALAGSNLCVDEAVVRHLLFPGKSEDITCQGSGTGDTN"
BASE COUNT          868 a          535 c          644 g          786 t
ORIGIN      
        1 aaacaattag gttaaacaaa agctaaacaa attaagtact gataattgac ttaccggtgt
       61 acatcaaaag aatcatatac atatgtagaa gtgacagaag ggagtcattg ttatgcaaac
      121 taagcttctg gcaattatgc ttgcagcacc tgtggtattc agttctcagg aagcttctgc
      181 ttctgatttc ttcggcccgg agaaaataag tacagagatt aatttaggta cactgagtgg
      241 caaaacaaaa gaacgggttt atgagcctga agaaggtgga cgtaaagtca gccaactgaa
      301 ctggaaatac agtaacgccg ccattcttaa aggcgccgtt aactgggagc tgaatccatg
      361 gttatctgtt ggtgcagctg gctggaccac tctcaatagt cgggggggga atatggttga
      421 tcaggactgg atggattccg ggactcccgg aacatggaca gatgaaagca ggcatcctga
      481 tacacgtctt aattatgcca acgaatttga tttgaacgtt aaaggctggt ttttaaaaga
      541 atctgattat cgccttgcta ttatggcagg ttatcaggaa agccgttaca gttttaatgc
      601 tacaggagga acttatattt acagtgagaa tggtggtttc cggaatgaaa cgggagcgtt
      661 acctgataaa ataaaagtga ttggttataa acaacatttt aaaattcctt atgtcggtct
      721 gacaggaaac taccgttacg ataattttga gtttggtggt gcatttaaat acagcgggtg
      781 ggtcagggga tctgataatg atgagcatta tgtaagacaa actacattcc gaagcaaagt
      841 aaaaaaccag aattactatt ctgttgcagt taatgccggt tactatatca ccccagaggc
      901 aaaagtgtac atcgagggtg tatggagtcg tctcacaaat aaaaaagggg atacatctct
      961 ttacgaccgt agtgataata cttcagagca taataataac ggggctggaa ttgaaaatta
     1021 caacttcatt acgacggccg gtctgaagta cacgttttaa caactttaac tgtcatcatc
     1081 tccggtgaga attataccgc cggagattct gtctgttggt cagcgtaata atttaccaat
     1141 gcaggagatg caatgcgtgt gataatgaag cctttaagaa ggactttagt attatttatc
     1201 ttttctgttt ttctttgcgg aactgtgtct gccagacaga tcgagtggca atcctgtatg
     1261 accagcccat acagtgactg gtttggtaca gaaagccctt cacctgagtt gttatgcgga
     1321 tatctatctg taccgctaaa atataccgac acaggtgggg atatgtcaga tgaaaatata
     1381 ccacttgtca gactggcgat gacaaagttg ccggcaaaaa gtaaacgtaa agggagtatt
     1441 attataataa gtggcggacc tggattaccc ggaattaatc cttatatcaa ttttgactgg
     1501 ccggtcacaa atcttcggga atcatgggac attatcggtt ttgatccacg aggtgtcggt
     1561 cagtcctttc ctgccataaa ctgccagcaa cccaatcaag aaagatcggt gaatgtaagc
     1621 gaaaagcaac taattttaca gaaaattaat gcctgtatcc ataatacagg agctgaagtc
     1681 attcgccata ttggatctca tgaggctgta tatgatattg aacgcatcag acaagctctg
     1741 ggagataaac aactgacagc tgtagcatat tcatacggta cacagattgc agccttatat
     1801 gccgaacgct ttccatccag tatcagatct atagtttttg acggtgtcgt tgatattgat
     1861 gatttaaatg ataatttttc atggaaactc aggcaggccc acagttatca ggaaacgttt
     1921 gatcgttttg ctgcatggtg tgccaggaca aaaagttgtc cactttcttc agacaggaat
     1981 caggcaatac atcagttcca tcagctttta ttaaaattac ataattctcc tttaacagac
     2041 agcagggggg aaagtatatc ttcagatgat ctcatatcat taacgacaga gcttctgtta
     2101 tggcgctcat catggccaac acttgcaacg gccgtacgtc agttctctca gggtattgtc
     2161 agcaatgaaa ttgaaactgc acttaattct tccatagcat cggaaaaagt cagtgatgct
     2221 ctgggtgtaa tattatgtgt tgatcagagt gatgaacaat tatcacagga acaacgaaaa
     2281 tcgcgcaaaa aagcccttgc tgacgcattt ccggccgtta attttgagag ggaacagtcc
     2341 gatttacctg aattttgtga attatggcca attcatcgcg atctgcaaca gacacgcctg
     2401 aagaatactg ttttaccatc cggtttactg tttgtggcac acaaatatga tccgacaact
     2461 ccctggataa atgcccgtaa aatggcagat aaattttcag ctccgttact gactattaac
     2521 ggtgacgggc atacgctggc gctagctggc tctaatttat gtgtggatga ggctgttgtt
     2581 cgtcacctcc tgtttccggg gaaatctgaa gatataacgt gtcagggaag tggtaccgga
     2641 gacactaact gatattaaat aaaatattac tcccgacatt aaataacatc agtgctttga
     2701 tgtcggggcc tgctaaccct cttttgatat cagttgagcg caggaaatgc cagttcagag
     2761 gggacaggac ttaggataaa taagagagtc gcaatcatga gtaagattca tgtacatgca
     2821 ggttacggaa aga
//
LOCUS       DAPHKZ010000245         2791 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.250, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000245 DAPHKZ010000000
VERSION     DAPHKZ010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2791
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.250"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            35..826
                     /locus_tag="RH288_004587"
     CDS             35..826
                     /locus_tag="RH288_004587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033543.1"
                     /translation="MTTRITFNMTSDETLRIVDEYCHTHKLSRSKVIDALLSATAPVL
                     NDINCYYQLAGELQSRLLNGVYQRDLPRKRNVVSAEKYCLEIWENKLFTRRVLEFDSS
                     NGVLYALKHKRHYRRDKMIGRVESRYIKDICEYQMQLSGEKTKYACFIYIERTIYNHD
                     NPSGETPVKAAVGNAVILLAKDVIYDEYFFDLRQSFFVSVKDLMASGAKGIPETQKYP
                     DVYCWIPLFSINSGVVITPVYKIDPRKPVTVKKPDQITVVCNYRE"
     gene            1209..1415
                     /locus_tag="RH288_004588"
     CDS             1209..1415
                     /locus_tag="RH288_004588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDV4033544.1"
                     /translation="MKTPVSLMDDQMVDMAFITQLTGLTDKWFYKLIKDGAFPAPIKL
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            1501..2073
                     /locus_tag="RH288_004589"
     CDS             1501..2073
                     /locus_tag="RH288_004589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033545.1"
                     /translation="MQKLENRCDLLLIQHQKWMASVTRFIVAHGMGSPHLHGYHRLTL
                     AHFFLPEKGTIISVAPQGLYQVVNPGTPPFIPAIQEGLMTSIQTHEIMLLTHFNLGGV
                     LLSELHRLGESRLANRLNSLLRRFEDRDLYHTLIWLCWYDLMCAHSMQPWTEELKHKS
                     HAELESWAVARKREKRELELMIDEYLLYAC"
     gene            complement(2075..2359)
                     /locus_tag="RH288_004590"
     CDS             complement(2075..2359)
                     /locus_tag="RH288_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033546.1"
                     /translation="MEVLNAPGKYQYDLRNHLLVDLFPIALDAEITTSNVNKHQLHRS
                     NIPATLSGNSGITGYVPFSAERNAARVIWRTATDSRPVVCNDEEGIPGAL"
     gene            2330..2476
                     /locus_tag="RH288_004591"
                     /pseudo
     CDS             2330..2476
                     /locus_tag="RH288_004591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT          780 a          679 c          590 g          742 t
ORIGIN      
        1 atatcaacca atatgattaa cagaaaactt catcatgaca acacgtataa ctttcaatat
       61 gaccagtgat gagacgctgc gaattgtgga tgagtactgt catacccaca aactttcgcg
      121 ctctaaggta atcgacgcat tactcagcgc cacagcacct gtccttaacg atattaactg
      181 ttattatcaa cttgcaggcg aactgcagtc acgcttatta aatggagtgt atcaacggga
      241 tcttcctcgc aaacgcaatg tcgtcagtgc agagaagtat tgtctggaaa tctgggaaaa
      301 caaacttttc accagaagag tcctggagtt tgacagttca aatggtgttc tgtacgcgct
      361 gaaacataaa agacactatc gccgagataa gatgattgga agggttgaaa gtcggtatat
      421 caaagacatt tgcgaatacc agatgcagct atccggggag aagacgaaat atgcctgttt
      481 tatttatatc gaaagaacaa tatacaatca cgataatcca tccggtgaaa cacctgtaaa
      541 agcggctgtt ggtaatgcag tcatcctgct ggcaaaagac gtgatatatg acgagtactt
      601 ttttgatctg cggcagtcat ttttcgtgag cgttaaagat ctgatggcct ctggcgcaaa
      661 aggtattccg gagacacaga aatatccgga cgtttattgc tggatcccgc ttttctccat
      721 aaattccggc gtggtcatta ccccggtcta taaaattgat ccccggaaac ccgtaacggt
      781 aaaaaaaccg gatcagatca ctgttgtttg taattacaga gaataatttc agtcttctcc
      841 gttcaccgca acagtgttta cctctgcttt atcttccttt cagtaaatac aaaccacagc
      901 tctggcaggt acagggcgtg gtttatctcc gatactcccc tgcgcagtaa taatcatcac
      961 tgaaaatact gattccgtca cggcaaaacg ccatcccata ttccggcaac acaaaatcat
     1021 cttccgttta taccggcttc actgacaaaa cagacaacct gtattgcctg tacacaacag
     1081 tttctctcct ggcaggaata ttcctcaact tttttacgtt tctccccggt tgttatgccg
     1141 gtgaaggtgg tgcgtcgttt tcatcaccaa cgccggttga gattaacaac atccggagga
     1201 acattttcat gaagacccca gtttcgctga tggatgacca gatggtcgac atggcgttta
     1261 tcactcaact gaccggctta accgataagt ggttttataa gctcatcaaa gatggtgcct
     1321 ttccggcccc catcaaactc ggccgcagct cccgatggct gaaaagtgaa gtggaagcct
     1381 ggttgcaggc gcgtattgca caatcccgtc cgtaattcct gaccgttatc cgttcaaccg
     1441 cagcgaatac actatccggc ctccggaggc attctgctgc gtgctaaagg agagaatatt
     1501 atgcaaaaac ttgaaaaccg atgtgatctg ctgctaattc agcatcagaa atggatggca
     1561 agtgtaaccc ggtttattgt cgctcatgga atgggctctc cgcatcttca tggttatcac
     1621 cgcctgaccc tggcccactt ttttctaccg gaaaaaggca ccatcatctc agtggcacca
     1681 cagggactct atcaggtcgt caacccggga acgccaccgt tcattcctgc cattcaggaa
     1741 gggttaatga ccagcattca gacccatgaa atcatgctgc ttacgcattt taatctgggc
     1801 ggcgttttac tcagtgagct acatcgtctg ggcgaaagcc ggctggcaaa caggctgaac
     1861 agtctgctcc ggcgtttcga agatcgcgat ctctaccaca cgctgatatg gctgtgctgg
     1921 tatgatctga tgtgtgccca ctccatgcag ccctggactg aagagttaaa gcataaatca
     1981 cacgcagagc ttgaaagctg ggctgtggcg cgcaaacggg aaaagcgcga gcttgaactg
     2041 atgattgacg agtatctgtt atacgcctgt tgattcataa cgctcccggg attccttcct
     2101 catcgttgca cacaaccgga cggctatctg tggcagtccg ccaaatgacc ctcgccgcat
     2161 ttcgttctgc tgaaaacggt acgtagccag tgataccgga atttccggag agggtcgcag
     2221 gtatattgct tctgtgcaat tgatgcttat ttacattgga tgtggttatt tctgcatcca
     2281 atgctatcgg aaagagatca accagcaaat ggttcctcaa atcgtattga tatttacccg
     2341 gtgcattgag cacctccatc tgacactccg ttcccgcatc aaacggctga accggaaaac
     2401 gatttgcttt tcacgctccg tggaaattca cgaaaaagtt attgggtcat tcatcgaaaa
     2461 acacatgttc tgctgactgg agccatcacc cggaaatata cgtcaactga acaataatga
     2521 ttttttcttt atgggatccc atacactttc ccatacccct ctgaaaatca gtcatcaact
     2581 caccaacaca tcttctgaaa tctgtattaa acttattgct taaatagatg atataacaca
     2641 tcttccattg cacggactca gcaaaaactg tcgttctggc aatcttaaca agatcactta
     2701 tcggttaatt tcatcagtaa acaatggaat atcacactga taaaatgaac actcagggtg
     2761 agatgataat atttacataa ataacattgc t
//
LOCUS       DAPHKZ010000246         2774 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.251, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000246 DAPHKZ010000000
VERSION     DAPHKZ010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2774
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.251"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(230..448)
                     /locus_tag="RH288_004592"
     CDS             complement(230..448)
                     /locus_tag="RH288_004592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033547.1"
                     /translation="MNNSNNLDYFTLYIIFSIAFMLITLLVILIAKPSTGLGEVLVTI
                     NLLNALVWLAINLVNRLRERLVNHRDQQ"
     gene            complement(580..2103)
                     /locus_tag="RH288_004593"
     CDS             complement(580..2103)
                     /locus_tag="RH288_004593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415686.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDV4033548.1"
                     /translation="MRNTLIPILVAICLFITGVAILNIQLWYSAKAEYLAGARYAANN
                     INHILEEASQATQTAVNIAGKECNLEEQYQLGTEAALKPHLRTIIILKQGIVWCTSLP
                     GNRVLLSRIPVFPDSNLLLAPAIDTVNRLPILLYQNQFADTRILVTISDQHIRGALNV
                     PLKGVRYVLRVADDIIGPTGDVMTLNGHYPYTEKVHSTKYHFTIIFNPPPLFSFYRLI
                     DKGFGILIFILLIACAAAFLLDRYFNKSATPEEILRRAINNGEIVPFYQPVVNGREGT
                     LRGVEVLARWKQPHGGYISPAAFIPLAEKSGLIVPLTQSLMNQVARQMNAIASKLPEG
                     FHIGINFSASHIISPTFVDECLNFRDSFTRRDLNLVLEVTEREPLNVDESLVQRLNIL
                     HENGFVIALDDFGTGYSGLSYLHDLHIDYIKIDHSFVGRVNADPESTRILDCVLDLAR
                     KLSISIVAEGVETKEQLDYLNQNNITFQQGYYFYKPVTYIDLVKIILSKPKVKVVVE"
     gene            complement(2435..2683)
                     /locus_tag="RH288_004594"
     CDS             complement(2435..2683)
                     /locus_tag="RH288_004594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033549.1"
                     /translation="MNNSIPERFIFQCALFKNLEREVFMTHGYVDSHIIDQALRLRLK
                     DETSVILSDLYLQILQYIEMHKTTLTDIIINDRESVLS"
BASE COUNT          859 a          586 c          568 g          761 t
ORIGIN      
        1 attttcatga cattgatcac tttgaggtga cgattttgtt taacaaataa ctcttcgaca
       61 tcaaaattgt taatagttgc gatgaggatt atttcggtga tatataaaaa caaccgtgat
      121 aacaccaggg ttgacaacta tttgcgcaat aatgcctttc cttcaatgat ccaggcgttc
      181 actgccagca acccattcag ccgcatactg acagtgagaa actgaaagat tattgctgat
      241 ccctgtggtt gacgagtctt tctcttaatc gattaaccag attgatcgcc agccaaacaa
      301 gggcattaag caaatttatc gtcacaagca cttctcccag cccggtactg ggttttgcaa
      361 taaggatgac caggagggtg atcagcataa atgcaatgga aaatatgata tagagagtga
      421 aataatccag attattacta ttgttcatgc tactaatggc aatcctgtca aaactttcaa
      481 acaattatag caaacaaaat aatgaacaat agtaacaaga ggcaacgagc taattagctg
      541 tctataatta caccgcacta tggccttact gatcaatttt cactcaacca caaccttcac
      601 cttcggttta gaaaggataa ttttgaccag gtcgatgtat gtaacaggtt tatagaaata
      661 ataaccctgc tgaaatgtga tattattttg gttcagatag tcaagttgtt ctttcgtttc
      721 gacaccttca gcgacgatac tgatcgaaag tttacgcgcc agatccaata cacaatccag
      781 aattcgggtt gattctgggt ctgcgtttac gcggccaacg aaactgtgat caattttgat
      841 ataatcaata tgcaggtcat gaagataaga aagccctgag tagccagtac cgaaatcatc
      901 cagtgcgatg acaaaaccat tttcatgcag tatgttcaac cgctgaacca gactttcatc
      961 aacattcaat ggctcacgct cggtgacttc cagaacaagg tttaaatcgc ggcgggtaaa
     1021 actgtcacgg aaatttaaac actcgtcgac aaacgtcggc gaaataatat gcgaagcgct
     1081 aaaattaatt ccaatatgaa aaccttccgg caatttactc gcgatagcgt tcatctgtct
     1141 ggcaacctga ttcatcaggc tttgcgtaag cggaacgatt aatccggatt tttcagcaag
     1201 tggaataaat gccgcgggtg atatatatcc accgtgaggt tgtttccagc gggctaacac
     1261 ctcaactccc cgcaatgtcc cttcccgacc atttaccaca ggttggtaaa aagggacgat
     1321 ctccccatta tttattgccc gtcgcaggat ctcttcaggc gttgcgcttt tattgaaata
     1381 tctatcaagc aggaaggcag cggcgcaggc gattaacaga ataaatatta aaatcccaaa
     1441 gcctttatcg ataagtctgt agaagctaaa gagtggcggc gggttaaaga taatagtgaa
     1501 atgatatttt gtggagtgaa ccttctcggt atagggataa tgtccattaa gcgtcatcac
     1561 atcacccgtt ggtccaataa tgtcatccgc cacgcgtaat acatacctta cccctttcaa
     1621 gggtacatta agtgccccac gaatatgctg atcgcttatc gtaaccaaaa tgcgcgtatc
     1681 tgcaaattgg ttctgataga gcaggatagg taatctatta acggtgtcga ttgctggagc
     1741 caacagtaaa ttactgtccg ggaaaacagg aatacgagac aacaggaccc gattcccagg
     1801 cagggatgta caccagacta ttccctgttt gagaatgatg attgtgcgca ggtgaggttt
     1861 cagagctgct tcagtgccaa gctgatattg ctcctcgagg ttgcattcct tcccggcaat
     1921 gttaaccgct gtttgagtcg cttgtgacgc ttcttcaagt atatgattga tattgttggc
     1981 ggcatatctc gctcccgcca ggtactctgc ttttgcggaa taccagagct ggatgttcaa
     2041 aatagcgaca ccggtaataa acaagcatat cgcaacgagg atgggtatga gtgtattgcg
     2101 catttgcttg tcccggccaa agggtttaat acatgaaaat gccattcatt cgctcgcgct
     2161 ggcatctaca gagagcatgg tagagagcat aagaaatatc cacgccgaag ataaaatttt
     2221 ctccatcttg atctaaccca ttaattattg agcataatgt aggcagtaca aaataagtta
     2281 ggcgggatat caggcgtcaa gaatggagag cgagaactct ccattcttga cacctgatat
     2341 tgcggacata ataagaaagc ataacgcctg aaatgctcac tttgcatcag catggtgata
     2401 cagctgatgt ttattctaaa accttactca agttctaaga gagcacggat tccctgtcat
     2461 taataatgat atccgttagt gtagtcttat gcatttcaat gtactgcaat atttgcagat
     2521 agagatcaga aagaatcaca ctggtttcat cttttaaacg caagcgtaaa gcctgatcaa
     2581 taatatgact atcaacatac ccatgcgtca tgaacacctc cctctcgaga tttttaaaca
     2641 aagcacattg aaaaataaat ctctctggga ttgaattatt catgtcagcc tcgtagaaat
     2701 attaacccaa taaaattatg ctgtgtatag tctaaagcga cagacaaaaa taagatgaat
     2761 gagttttcta taaa
//
LOCUS       DAPHKZ010000247         2612 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.252, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000247 DAPHKZ010000000
VERSION     DAPHKZ010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2612
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.252"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            11..751
                     /locus_tag="RH288_004595"
     CDS             11..751
                     /locus_tag="RH288_004595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HDV4033550.1"
                     /translation="MFFNTKHTTALCFVTCMAFSSSSIADIVISGTRVIYKSDQKSVN
                     VRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTAST
                     SLPKDRESVFWFNVLEVPPKPDAEKVANQSLLQLAFRTRIKLFYRPDGLKGNPSEAPL
                     ALKWFWSGSEGKASLRVTNPTPYYVSFSSGDLEASGKRYPIDVKMIAPFSDEVMKVNG
                     LNGKANSAKVHFYAINDFGGAIEGNARL"
     gene            786..>2612
                     /gene="htrE"
                     /locus_tag="RH288_004596"
     CDS             786..>2612
                     /gene="htrE"
                     /locus_tag="RH288_004596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Yad fimbria usher protein HtrE"
                     /protein_id="HDV4033551.1"
                     /translation="MTIEYTKNYHHLTRIATFCALLYCNTAFSAELVEYDHTFLMGQN
                     ASNIDLSRYSEGNPAIPGVYDVSVYVNDQPIINQSITFVAIEGKKNAQACITLKNLLQ
                     FHINSPDINNEKAVLLARDETLGNCLNLTEIIPQASVRYDVNDQRLDIDVPQAWVMKN
                     YQNYVDPSLWENGINAAMLSYNLNGYHSETPGRKNESIYAAFNGGMNLGAWRLRASGN
                     YNWMTDSGSNYDFKNRYVQRDIASLRSQLILGESYTTGETFDSVSIRGIRLYSDSRML
                     PPTLASFAPIIHGVANTNAKVTITQGGYKIYETTVPPGAFVIDDLSPSGYGSDLIVTI
                     EESDGSKRTFSQPFSSVVQMLRPGVGRWDISGGQVLKDDIQDEPNLFQASYCYGLNNY
                     LTGYTGIQITDNNYTAGLLGLGLNTSVGAFSFDVTHSNVHIPDDKTYQGQSYRVSWNK
                     LFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPEQDLEPKSMRNYSRMKNQVTV
                     SINQPLKFEKKDYGSFYLSGSWSDYWASGQNRSNYSIGYSNSTSWGSYSVSAQRSWNE
                     DGDTDDSVYLSFTIPIEKLLGTEQRTSGFQSIDTQISSDFKGN"
BASE COUNT          746 a          564 c          573 g          729 t
ORIGIN      
        1 gggatggttt atgtttttca acaccaaaca tacaacagct ttatgcttcg taacctgtat
       61 ggcttttagt tcatcgtcta ttgcggacat tgtcatttcg ggtactcgcg taatatataa
      121 aagcgatcaa aaaagtgtca acgtacgtct ggaaaataaa gggaataacc cgttgcttgt
      181 ccagagttgg ttagatactg gcgatgacaa cgctgagcct ggcagtatta cagtcccttt
      241 tactgctacg ccgccagtat cgcgtattga tgccaaacgt gggcaaacaa tcaaattaat
      301 gtacacagcc agcacctcac tgcctaaaga cagagagagc gtgttctggt ttaacgtact
      361 ggaagttcca ccaaaaccag atgcagaaaa ggtcgcgaat caaagcctgc tgcaactggc
      421 atttcgcaca cgtataaaac ttttctatcg cccggatgga ttgaagggaa atccctctga
      481 agccccgtta gccctgaagt ggttctggtc aggttcagaa ggtaaggcgt cattacgagt
      541 gaccaatcca accccttact acgtctcttt tagcagtggt gatttagaag ctagcggtaa
      601 acgctatccg attgatgtga aaatgattgc accatttagt gatgaggtca tgaaagtcaa
      661 tggccttaat ggcaaagcga attctgcaaa agtgcatttt tacgccatta atgactttgg
      721 tggcgcaatt gaaggtaatg ccaggctgta atcaggcaag gatataattc cgcaggaagc
      781 atagcgtgac tatagaatat actaaaaatt atcatcatct gacccgtatc gccacgtttt
      841 gcgcgctgct gtattgcaat actgctttca gtgctgaact cgttgaatat gaccatacct
      901 tcctgatggg gcagaatgca tctaatattg atctcagccg gtacagtgaa ggtaaccccg
      961 ctataccggg tgtttacgac gtcagtgttt atgtaaacga ccaaccaatc attaaccaaa
     1021 gtattacatt tgtcgcaatt gaaggaaaaa agaacgccca ggcttgtatc acattaaaga
     1081 atttattgca gtttcatatt aattctcccg atataaataa cgaaaaagcc gttctgcttg
     1141 ccagggatga aacgctcggc aattgcctca atttgacgga aattatccct caggcttctg
     1201 ttcgttatga cgttaacgat caacgtctgg atatagacgt tcctcaagcc tgggtaatga
     1261 aaaattacca aaactatgtt gatccatcgt tatgggaaaa cggcattaat gcggccatgt
     1321 tgtcatacaa cctcaacgga tatcatagtg aaacccctgg tcgaaaaaat gaaagcattt
     1381 atgctgcatt taacggtggg atgaatttag gtgcatggcg actgcgtgcc tcgggcaact
     1441 acaactggat gaccgattct ggcagtaatt atgattttaa gaatcggtat gttcagcgtg
     1501 atatcgcctc gctgcgttct caactcattc ttggtgagtc ttatacgacg ggcgaaacct
     1561 ttgattccgt cagtatccga ggcattcgtt tatacagtga cagccgcatg ttgcctccga
     1621 ctttagccag ctttgcgcct atcattcatg gcgttgccaa taccaacgcc aaagtcacta
     1681 ttacgcaagg tggctataag atttatgaaa cgacggtgcc gccaggcgct ttcgtcattg
     1741 atgatctgag tccgtcaggg tacggcagcg atcttattgt taccatcgaa gaatccgatg
     1801 gctcaaagcg gacattctcg caacctttct catccgttgt tcaaatgtta cgccctggcg
     1861 ttggacgttg ggatattagc ggcggtcagg tcttaaaaga tgatattcag gatgagccta
     1921 atttatttca agcaagctac tgctacggcc tgaataacta tctgacgggt tataccggta
     1981 ttcagataac cgataataac tataccgctg gtttgttagg tcttggtctg aatacttcag
     2041 ttggtgcatt ttctttcgat gtgactcatt ccaatgttca tatcccggat gataaaacat
     2101 accaggggca aagttatcgt gtttcctgga acaagttatt cgaagaaaca agtacttcac
     2161 tgaatatcgc ggcctatcgc tattcgacac agaattacct tggtcttaat gatgcactaa
     2221 ctctaattga tgaagtgaaa catcccgaac aagatcttga accgaaatcc atgcgtaatt
     2281 actcacgcat gaaaaatcag gttacggtca gtattaacca accgttgaaa tttgagaaaa
     2341 aagattacgg ttcattttat ctttccggaa gttggtccga ttactgggct tccggacaaa
     2401 atcgtagcaa ttactctatt ggctacagta acagtacatc ctggggcagc tacagtgtca
     2461 gtgcccagcg ttcatggaat gaagacggcg acactgacga tagcgtttat cttagtttca
     2521 ccattccaat tgaaaaatta cttggcactg aacaacgtac ttcaggtttc cagagtattg
     2581 atactcaaat aagcagtgac tttaagggta at
//
LOCUS       DAPHKZ010000248         2597 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.253, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000248 DAPHKZ010000000
VERSION     DAPHKZ010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.253"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            364..507
                     /locus_tag="RH288_004597"
     CDS             364..507
                     /locus_tag="RH288_004597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HDV4033552.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAK
                     KTI"
     gene            520..729
                     /gene="cspE"
                     /locus_tag="RH288_004598"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             520..729
                     /gene="cspE"
                     /locus_tag="RH288_004598"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HDV4033553.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            895..1704
                     /gene="rlmA"
                     /locus_tag="RH288_004599"
     CDS             895..1704
                     /gene="rlmA"
                     /locus_tag="RH288_004599"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HDV4033554.1"
                     /translation="MSFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRERLDDKATAVLDIGCGEGYYTHA
                     FADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCK
                     AEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQQSAELCY
                     PMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRSY"
     gene            complement(1701..2267)
                     /gene="mntP"
                     /locus_tag="RH288_004600"
     CDS             complement(1701..2267)
                     /gene="mntP"
                     /locus_tag="RH288_004600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HDV4033555.1"
                     /translation="MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRR
                     HGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGS
                     IIGKKAEILGGLVLIGIGVQILWTHFHG"
BASE COUNT          694 a          603 c          622 g          678 t
ORIGIN      
        1 ctctttaggg taattgatag ccgttaactg actgttttat gagaaaaagt gatataactt
       61 tttattcatt gcatagcaaa aaatgtgata ttgcacgcac tatgtaataa cttctcccac
      121 tggcctggaa caactgaact tattgaacta tgttagaaac tacgccagtt taagtatctg
      181 cctgaactgg caaggttaag cacaatgata tatcggcgcg tattccgttg cataagtgtg
      241 caaaaaaagt ggaagacgta tcgagatttg tgcgtctgat cgagacatgt ttaaaaatgg
      301 cttgccataa ttaacgttgt atgtgataac agatttcggg ttaaacgagg tacagttctg
      361 tttatgtgtg gcattttcag taaagaagtc ctgagtaaac acgttgacgt tgaataccgc
      421 ttctctgccg agccttatat tggtgcctca tgcagtaatg tgtcagtttt atctatgtta
      481 tgcctgcggg cgaagaaaac aatctaagga atttttcaaa tggcaaagat taaaggtcag
      541 gttaagtggt tcaacgagtc taaaggtttt ggcttcatta ctccggctga tggcagcaaa
      601 gacgtgttcg tacacttctc cgctatccag ggtaatggct tcaaaactct ggctgaaggt
      661 cagaacgttg agttcgaaat tcaggacggc cagaaaggtc cggcagctgt taacgtaaca
      721 gctatctgat cgaatccact gatctgaagt gtgaatacgc ttcaatctcg ctataaagcc
      781 tcgtcgaatg cgaggctttt tactatgctt tatcttcgct cctggcgttc ggatatttgc
      841 ccgccgcgtg attcgcgtta cacttgcggc ctttagtatc ctgccggagt tgtcatgtct
      901 ttttcctgtc cactttgcca tcagcctctt tcgcgtgaaa aaaacagcta tatctgtccc
      961 cagcgacatc agtttgatat ggcgaaagaa gggtatgtca atctgctgcc cgttcagcat
     1021 aaacggtctc gtgatccggg cgacagcgcg gaaatgatgc aagcacgccg cgcattctta
     1081 gatgccggac attatcagcc gctgcgtgat gcaattgtcg cccaactgag ggaacggctt
     1141 gatgataagg ccacggcggt gctggatatt ggctgtggtg aagggtatta cacacacgca
     1201 tttgccgatg cgttgcccga aatcaccacg tttggtctgg atgtttcgaa ggtagcgata
     1261 aaagcggcgg cgaaacgcta tccgcaggtc actttttgtg tcgcttccag ccaccgtttg
     1321 ccgttttccg ataccagtat ggacgccata atacgtattt acgcgccgtg taaagcagaa
     1381 gaattagcac gagtagtgaa gcccggcggc tgggtcatta ctgccacgcc gggaccgcga
     1441 catttgatgg agctgaaggg gctgatttac aatgaagtac atcttcatgc acctcatgca
     1501 gaacaactgg aaggttttac attacagcag agtgcggagt tgtgttatcc gatgcgtctt
     1561 cgcggtgatg aagccgtcgc attattgcag atgacgccgt ttgcctggcg tgcgaagcca
     1621 gaagtctggc aaacactggc agcaaaagaa gtgttcgact gccagacgga ctttaatatt
     1681 cacctctggc agcgttctta ttaaccgtgg aagtgcgtcc agaggatctg gacgccgatg
     1741 ccgatcagca ccagcccgcc gagaatttcc gcttttttcc caataattga gccgataaag
     1801 cgaccaacca tcatccctaa tgttgacata atcaaggttg cacaaccaat ggccaatgcg
     1861 gtcgcgataa tgttgacctg caggaaagca agaccaacac ccacagccat ggcatccagg
     1921 ctggtggcaa tcgcggtggt taccagtagc cagaaaccgt gtcgacggcg cggctcttca
     1981 tcttcatcat ctgcgccacg aaaaccctca ataatcattc gcccgccgag gaatatcagc
     2041 agcacaaacg caatccagtg gttccattcg aggacaaacc ggctggctaa catgcccatt
     2101 ccccagccga tcagcggcgt cagggtttcg acggcaccaa aaataaggcc ggttcgcaat
     2161 gcttcagaaa atttcggttt atggagggtg gcacctttac cgattgatgc agcaaatgca
     2221 tccatcgaca taccaaacgc aagaagaaca gtagcagtga tattcatgac aatgtcctga
     2281 ccggggtatc cataaaacac atcatcgccc ccagcaaaca tgcatacatg aacaacaagc
     2341 cgtgatggtt ttcgcgttca tgcaggcata gcgattgatg tgcatatggt ctcgcctgac
     2401 tgaaagtatt cagtccgtac gtgccacgtt ttgcaacgag tatgttgaca cgtacatttc
     2461 cggaatctgg aaatcggcta ctccccaaat gagggcgcaa ccttaacata ttttgagaat
     2521 ataaaacaac tgttggaata tattatttca ttgctttatt gataacgatt ttcatttaga
     2581 tttatatatc aatgaaa
//
LOCUS       DAPHKZ010000249         2550 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.254, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000249 DAPHKZ010000000
VERSION     DAPHKZ010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2550
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.254"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>2550
                     /gene="rhsC"
                     /locus_tag="RH288_004601"
     CDS             <1..>2550
                     /gene="rhsC"
                     /locus_tag="RH288_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhs element protein RhsC"
                     /protein_id="HDV4033556.1"
                     /translation="RYGWTPRGELAAVYDRSNTQVRSFTYDDKYRGRMVAHRHTGRPE
                     ICYRYDSDGRVTEQLNPAGLSYTYQYEKDRITITDSLNRREVLHTQGEGGLKRVVKKE
                     HADGSVTQSQFDAVGRLRAQTDAAGRTTEYSPDVVTGLITRITTPDGRASAFYYNHHS
                     QLTSATGPDGLEIRREYDEWGRLIQETAPDGDITRYRYDNPHSDLPCATEDATGSRKT
                     MTWSRYGQLLSFTDCSGYVTRYDHDRFGQVTAVHREEGLSQYRAYDSRGQLIAVKDTQ
                     GHETRYEYNAAGDLTTVIAPDGSRNGTQYDAWGKAICTTQGGLTRSMEYDAAGRVIRL
                     TSENGSHTTFRYDVLDRLIQETGFDGRTQRYHHDLTGKLIRSEDEGLVTHWHYDEADR
                     LTHRTVNGETAERWQYDERGWLTDISHISEGHRVTVHYGYDSKGRLASEHLTVHHPQT
                     NELLWQHETRHAYNAQGLANRCIPDSLPAVEWLTYGSGWLSGMKLGDTPLVEYTRDRL
                     HRETLRSFGRYELTTAYTPAGQLQSQHLNSLLSDRDYTWNDNGELIRISSPRQTRSYS
                     YSTTGRLTGVHTTAANLDIRIPYTTDPAGNRLPDPELHPDSALSMRPDNRIARDAHYL
                     YRYDRHGRLTEKTDLIPEGVIRTDDERTHRYHYDSQHRLVHYTRTQYAEPLVESRYLY
                     DPLGRRVAKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGS
                     FTPLIRVETATGELAKTQRRSLADTLQQSGGEDGGSVVFPPVLVQMLDRLESEILADR
                     VSEESRRWLASCGLTVEQMQNQMDPVYTPARKIHLYHCDHRGLPLALVSTEG"
BASE COUNT          605 a          779 c          776 g          390 t
ORIGIN      
        1 cgctatggct ggacgccccg cggcgaactg gcggcggtgt atgaccgcag caatacacag
       61 gtgcgcagct ttacttacga tgataaatac cggggccgga tggtggcgca ccgtcacacg
      121 ggccgaccgg aaatctgtta ccgttacgac agcgacgggc gggtgacaga acagctaaac
      181 ccggcaggct taagttacac gtatcagtat gagaaggacc gcatcaccat caccgacagc
      241 ctgaaccgcc gtgaagtcct gcacacgcag ggtgaaggcg ggctgaagcg ggtggtgaaa
      301 aaggaacacg cggacggcag cgtcacgcag agtcagtttg acgcggtggg caggctcagg
      361 gcacagacgg atgccgcagg caggacaaca gaatacagtc cggatgtggt gacgggcctc
      421 atcacgcgca tcaccacgcc ggatggcagg gcatcggcgt tttactataa ccaccacagc
      481 cagttaacgt cagccaccgg gcctgacggg ctggaaatac gccgggaata tgatgaatgg
      541 ggccgtctga ttcaggaaac tgcccctgac ggcgatatca cccgctaccg ttatgataat
      601 ccacacagtg acttaccctg cgcaacggaa gatgccaccg gcagccggaa aaccatgacg
      661 tggagccgtt acggtcagtt gctgagcttc actgactgtt ccggttatgt aacccgctat
      721 gaccatgacc gttttggtca ggtgacggcg gtgcaccgcg aggaagggct gagtcagtac
      781 cgcgcatacg acagccgtgg acagttaatt gccgtgaaag acacgcaggg ccatgaaacg
      841 cggtatgaat acaacgccgc cggtgacctg accaccgtca ttgccccgga cggcagcaga
      901 aacgggacac agtacgatgc gtggggaaaa gccatctgta ccacgcaggg cggtctgacg
      961 cgcagtatgg aatacgatgc tgccggacgg gtcatccgcc tgaccagtga aaacggcagc
     1021 cacaccacct tccgttacga tgtactcgac cggctgatac aggaaaccgg ctttgacggc
     1081 cgcacacagc gttatcacca cgacctgacc ggcaaactta tccgcagcga ggatgagggg
     1141 ctggtcaccc actggcacta tgacgaagca gaccgcctca cgcaccgcac cgtgaatggc
     1201 gaaaccgcag agcggtggca gtatgacgaa cgcggctggc tgacagacat cagccatatc
     1261 agcgaagggc accgggtgac ggtgcactat ggttatgaca gtaaaggccg cctcgccagt
     1321 gaacacctga cggtgcatca tccgcagacg aatgaactgc tctggcagca tgagaccaga
     1381 catgcgtaca acgcacaggg actggcgaac cgctgtatac cggacagcct gcccgccgtg
     1441 gaatggctga cctacggcag cggctggctg tcaggcatga aactcggcga cacaccgctg
     1501 gtggagtaca cccgcgaccg cctgcaccgg gaaacgctgc gcagcttcgg ccgttatgaa
     1561 ctcaccaccg cttatacccc tgccgggcag ttacagagcc agcacctgaa cagcctgctg
     1621 tctgaccgcg attacacctg gaacgacaac ggcgaactca tccgcatcag cagcccgcgc
     1681 cagacccgga gttacagcta cagcaccacc ggcaggctga ccggcgttca caccaccgca
     1741 gcgaatctgg atatccgcat cccgtatacc acagacccgg caggtaaccg cctgcccgac
     1801 ccggagctgc acccggacag cgccctcagc atgcggccgg ataaccgtat cgcccgtgac
     1861 gcgcactatc tttaccggta tgaccgtcac ggcaggctga cagagaaaac cgacctcatc
     1921 ccggaagggg ttatccgcac ggatgatgag cgcacccacc ggtaccatta cgacagtcag
     1981 caccggctgg tgcactacac gcggacacaa tatgcagagc cgctggtcga aagtcgctat
     2041 ctttacgacc cgctgggccg cagggtggca aaacgggtat ggcggcgtga acgggacctg
     2101 acgggctgga tgtcgctgtc acggaaaccg caagtgacct ggtacggctg ggacggcgac
     2161 cgcctgacca cgatacaaaa cgacagaacc cgcatccaga cgatttatca gccggggagc
     2221 ttcacgccac tcatcagggt tgaaaccgcc accggtgagc tggcgaaaac gcagcgccgc
     2281 agcctggcgg atacccttca gcagtccggc ggcgaagacg gtggcagtgt ggtgttcccg
     2341 ccggtgctgg tgcagatgct cgaccggctg gaaagtgaaa tcctggctga ccgggtgagt
     2401 gaggaaagcc gccgctggct ggcatcgtgc ggcctgacgg tggagcagat gcaaaaccag
     2461 atggacccgg tgtacacgcc ggcgcgaaaa atccacctgt accactgcga ccatcgcggc
     2521 ctgccgctgg cgcttgtcag cacggaaggg
//
LOCUS       DAPHKZ010000250         2547 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.255, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000250 DAPHKZ010000000
VERSION     DAPHKZ010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2547
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.255"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..255)
                     /locus_tag="RH288_004602"
     CDS             complement(<1..255)
                     /locus_tag="RH288_004602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HDV4033557.1"
                     /translation="MVKKPSQQALNRAAVTVEQAEALAQRLADKPYGAPEKPEPEKQC
                     RTTISLGESMLVTIEDLALRNKRNGKDPKNVSAIVRVALEQ"
     gene            complement(249..893)
                     /locus_tag="RH288_004603"
     CDS             complement(249..893)
                     /locus_tag="RH288_004603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDV4033558.1"
                     /translation="MITVVGGNKGGSGKTTIASNLAIALANKGREVCLLNGDLQRTAA
                     KHHAEREAAGLLPAITLVEKFDNLTQTLQALNEKFDDVIVDVAGRNSKEFITSGVVAH
                     QIIAPLQCSQPDLDTLTELEQQIDAMRNLNPELKVYCLQSMATTNPVLRGNERKEFLE
                     YLEEFPTIQVLDSVICFRKVYRDCMSNGTGVVETNNTAAKAEIEHLMNEVFGPW"
     gene            1122..2093
                     /locus_tag="RH288_004604"
     CDS             1122..2093
                     /locus_tag="RH288_004604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein parM"
                     /protein_id="HDV4033559.1"
                     /translation="MNVYCDDGSTTIKLAWNDNGKICKSLSQNSFRHGWKVDGLGIRQ
                     TFNYELDGKKYTYDEVSNQSILTTHIEYQYTDVNLLAVHHALLNSGLAPQPVSLTVTL
                     PISEFYTKECQKNELNIQRKIENLMRPIRLNKGDVFTIEHVDVMPESLPAVFSRLVVD
                     KVGQFEKSLVVDIGGTTLDVGVIVGQFDSVSAIHGNSGIGVSSVTKAAMSALRMASSD
                     TSFLVADELIKRRNDPDFVRQVINDETKTDLVLNTIEGAIASLGEQVVNELGDFHHVN
                     RVYVVGGGAPLIYDSIKTAWHHLGQKVVMMESPQTALVEAIAAFKEE"
     gene            2098..2490
                     /locus_tag="RH288_004605"
     CDS             2098..2490
                     /locus_tag="RH288_004605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HDV4033560.1"
                     /translation="MDDERKRKKYTLYLHPEKAADFQTLEAIESVPRSERGELFRNAF
                     ISGMALHQLDPRLPVLLTAILSEEFSADQVVTLLSQTTGWKPSQADIRAVLTELGASQ
                     SVEKMPPSATDSVQEAMNDVRLKMKKLF"
BASE COUNT          664 a          489 c          583 g          811 t
ORIGIN      
        1 ttgctcaagg gctactctga cgatggcact tacatttttt ggatctttac cattgcgttt
       61 attcctcaat gccagatctt ctattgtgac aagcatgctt tcaccaagag agattgtcgt
      121 ccgacattgt ttttctggtt cgggtttttc cggcgcgccg tatggtttat ccgcaaggcg
      181 ctgagccaga gcctctgctt gttctaccgt aactgcagct ctgtttaatg cttgctggct
      241 gggtttcttc accatgggcc aaatacctca ttcattaaat gttcaatttc tgctttggct
      301 gctgtattgt tcgtttctac tacaccggtg ccgttgctca tgcaatcgcg atagactttt
      361 ctgaaacaaa taactgaatc aaggacttga attgttggga attcttcaag atattcaagg
      421 aattcttttc tctcatttcc cctcaaaacc ggattggttg ttgccatact ttgtaaacaa
      481 taaaccttaa gttccgggtt aaggttacgc attgcgtcta tctgttgttc tagttctgta
      541 agagtatcca gatctggttg agaacactgt agtggcgcaa ttatttgatg tgcgacaact
      601 ccactcgtta tgaattcctt tgagtttctt cctgcgacat ccactattac atcatcgaac
      661 ttttcattca gagcctgtag tgtttgtgtc aggttatcaa atttctcaac aagggttatt
      721 gctggtaaca gtcctgcagc ttctcgttcc gcatgatgtt ttgcggctgt tcgttgtaga
      781 tctccgttta acaggcagac ttcccttcct ttatttgcga gagcaatagc caggtttgat
      841 gcaatggtag ttttccctga accacctttg ttcccaccaa ctacagtaat cattgcaacc
      901 tcataaatgt gatatgtgaa gtatgatgat attttgacac ggtaacctga ggtgtcaata
      961 tgtgttcata tttatgaagt atgaaatatg aagtgcgtta tgtgatgtaa taaataatac
     1021 ttgtgttttg tgatttcata actatgatag tgctcaaatt gagtattacc ttgcaactag
     1081 aaacaatgat ttactcagat tgagtattta aggggctata gatgaacgta tactgcgatg
     1141 atggttcaac aacaatcaag ttggcatgga atgataatgg aaaaatctgt aagtcgttgt
     1201 cgcaaaactc atttcgtcat ggatggaagg ttgacgggtt aggaattcgc cagacattta
     1261 actatgaact ggatggtaaa aaatacacgt atgatgaagt tagcaaccaa tctattctta
     1321 cgactcatat tgagtatcaa tatacggatg ttaacctgtt agctgtgcat cacgctttac
     1381 tgaatagtgg attagcgcct cagcctgtat cattgactgt gactttgcct atcagtgagt
     1441 tctatacgaa agagtgtcaa aaaaatgaac tcaacattca gcgtaaaatt gagaatttaa
     1501 tgaggccgat tcgtcttaat aaaggcgatg ttttcaccat tgaacacgtt gatgtgatgc
     1561 ctgaatcatt gccagctgtg ttttctcgtc tggtcgtgga taaagttggt cagttcgaaa
     1621 aatcgctggt agttgatatt ggcggcacta cgcttgatgt tggtgttatc gttggtcaat
     1681 ttgactctgt aagtgccatt catggtaatt ctggcattgg tgtgtcttca gttacgaaag
     1741 ctgcaatgag tgcattgcgc atggcatcca gtgataccag tttcctcgtt gcagatgaat
     1801 tgattaaacg tcgtaatgac ccggactttg ttcggcaggt tataaatgac gaaacaaaaa
     1861 ctgatctggt ccttaatacc attgaggggg ctattgccag tttgggggag caagtagtca
     1921 atgagctcgg tgatttccat catgtgaatc gtgtttatgt tgtcggtggt ggggccccgt
     1981 tgatctatga ttcgataaaa acggcatggc accatcttgg gcaaaaagta gtgatgatgg
     2041 agtcgccaca gacagcactg gttgaagcta tcgcggcttt caaagaggag taatattgtg
     2101 gacgatgaac ggaaaaggaa aaaatacaca ctttatctgc atccggaaaa agctgcagac
     2161 tttcaaactt tggaagcgat agagtccgtt ccgcgttctg agcgtggtga gctgttccgg
     2221 aatgcattta tttctggaat ggcgttacac caacttgatc ctcgcctgcc tgtattgctg
     2281 acagccattt tgagcgagga gttttcagca gatcaggttg taaccttact cagtcagacg
     2341 actggatgga agccttctca ggccgatatc agagctgtgt tgactgaact cggtgcttcg
     2401 caatctgttg aaaaaatgcc tccttctgct actgattcgg tgcaggaggc aatgaatgat
     2461 gtgcgtctta aaatgaaaaa attattctga tatatcagaa tgaagcaatg gggatctcag
     2521 tccattgtgt tgtatacgaa ggcgata
//
LOCUS       DAPHKZ010000251         2528 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.256, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000251 DAPHKZ010000000
VERSION     DAPHKZ010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2528
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.256"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            131..442
                     /locus_tag="RH288_004606"
     CDS             131..442
                     /locus_tag="RH288_004606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033561.1"
                     /translation="MIIDKEYALVNATARLNTDLRDYEYEINNAAIITFGNDLIEVIV
                     YQFSFVISIRAEGEKIKHGLLVNFGKNIARQVSSLCASAMRVYPNEKHKPSRQLFHCI
                     N"
     gene            516..2381
                     /locus_tag="RH288_004607"
     CDS             516..2381
                     /locus_tag="RH288_004607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDV4033562.1"
                     /translation="MAGQYEKAITIKQAIDSINLRHYLLPAIQRKFVWSSSQICLLFD
                     SIMRDYPINSFMMWDIRSASIKNDYKFYEFLKEYCQRFNEENPCVATNAGFHDFKAVI
                     DGQQRLTSLYIGLCGTYAYKQPRMWWPSAQDDRILPPRKLYVDLTAPLKSDDELMMKY
                     NFRFLTEKQYTDSLADNKHHWFCLHEIFKYEQHDSPDDILFNVVVPELEKRDLISSEF
                     SRKTLLKLYTKIRTENLIHYFNESSQDIDHVLDVFIRTNSGGTKLEFSDLLMSIAVAH
                     WQGDFRRELDELTKNIYQNNEMGFYIERDWFLKTSLMLIDSDVRFKVKNFTSEEVGKI
                     QQQWSEIKSCIKETFILIRRFGINPQSLISKNAVIPVVYWLYKKQTSGHPLYTTINLL
                     NKNHNERSVISQWFYMVLLKGIFGSQADALLTSIRDVMKNSLSDIHFPLEKIIDRYKG
                     SNKDLRFDDEYIESLLNIRYGEGRCRALLHLLFPEMNPTEVFHIDHLHPRNHFSKKYL
                     EKLDYVANTPENLSFYENPEHWDTIPNLHLLNHSQNISKQDTSLKQWLSHSSNNYTPS
                     MLLVSDDNIEFSRFPEFYNERRNALKQRLLNRVFLTSKIDSSPSTMDTDEEILTD"
BASE COUNT          839 a          513 c          495 g          681 t
ORIGIN      
        1 gggccagtct acatgaacat tattcatcag ataatgcatt acgggagtaa acagacgaat
       61 aatcgtaatt aaaatcacaa catattatta gtgatgatta aatcacatta acatgataag
      121 tgagaaagtt atgattatcg ataaagaata cgcacttgta aatgcaacag caagacttaa
      181 cactgacctg agggattatg aatatgaaat aaacaacgcc gccatcataa catttggcaa
      241 tgacctcatt gaggtaatcg tatatcagtt cagctttgtc atcagcatca gggcagaggg
      301 tgaaaaaata aagcacggcc tacttgttaa cttcggtaaa aatatagcaa gacaggtttc
      361 atcactttgt gcatccgcaa tgcgagtcta cccgaatgaa aaacacaaac cgagccgtca
      421 gcttttccat tgcataaatt agtttgtgca aagactgtac taccgacacg caataaatta
      481 aaataggcca gctaatataa catatgaggt ttatgatggc tggccagtat gaaaaagcaa
      541 taacgataaa acaagcgata gattcaatta atttacgcca ctatcttctg cctgcaattc
      601 agagaaagtt cgtctggagc agcagtcaga tatgtttgct gtttgattcc atcatgcgag
      661 actacccgat aaactctttc atgatgtggg atatccgtag tgccagtatt aaaaatgatt
      721 acaaattcta tgagttcctg aaagaatact gtcagcgatt taatgaagaa aacccctgcg
      781 tagcaacaaa tgctgggttt catgatttca aggccgtgat tgatggtcag cagcgtctca
      841 catcattata tattggattg tgtggaacgt atgcgtataa acagccccgg atgtggtggc
      901 cttcggcaca ggatgatcgc atcctgccac ccagaaagct ttacgtcgat ttaacagcgc
      961 cacttaagtc agacgatgag ctcatgatga agtataactt caggttcctg accgagaagc
     1021 aatatactga ttcacttgcc gataacaaac atcactggtt ctgcctgcac gaaatattca
     1081 aatacgagca acatgattcg cctgatgata ttttatttaa cgttgtcgta ccagaacttg
     1141 aaaaaagaga tctcatttcc agtgaatttt ccagaaaaac tctgcttaaa ctttatacca
     1201 agataagaac tgagaatctt atccactact tcaatgagag cagtcaggac attgatcatg
     1261 tgctggatgt tttcatccgc acgaacagcg gggggacaaa acttgagttt tcagacttac
     1321 tgatgtcaat agcggtagcg cactggcagg gtgatttcag aagagaactg gatgaactga
     1381 caaaaaatat ttatcagaac aacgagatgg ggttttatat tgaaagagac tggttcttaa
     1441 aaaccagcct gatgcttatt gactctgacg tccggttcaa agtaaaaaac ttcacttcag
     1501 aggaggtcgg taagatacaa cagcaatggt ctgaaataaa atcctgtatc aaggagactt
     1561 ttattcttat caggcgattc ggcatcaatc cacagtcttt gatatctaaa aatgcagtca
     1621 ttcctgtggt ctactggctt tacaaaaagc aaaccagtgg acatccatta tatacaacga
     1681 ttaatctcct gaataagaac cacaatgaac gctcagtaat tagccagtgg ttttacatgg
     1741 tacttctgaa agggatcttt ggaagccagg ccgatgcgct actcacgagc atcagagatg
     1801 taatgaaaaa tagtctttca gatattcatt ttcctcttga gaagattatt gacagatata
     1861 aaggctcgaa taaggacctc agatttgacg acgaatacat cgaaagcctt ctcaatatca
     1921 gatatggcga aggtcgttgc cgtgcactat tgcatcttct gttccctgaa atgaatccga
     1981 ccgaggtgtt tcatattgat caccttcacc caagaaatca tttttcaaag aaatatcttg
     2041 aaaaattaga ttatgttgcg aatacaccag agaacctcag cttttatgaa aatccggagc
     2101 actgggacac catacctaat cttcatttac tgaatcactc tcagaatata agtaaacagg
     2161 atacatccct gaaacaatgg ctatctcatt catcaaacaa ctatacgcca tcaatgttgt
     2221 tagtttcaga tgacaatatt gagttcagtc gcttcccgga attctacaat gagcgaagaa
     2281 acgccctgaa gcaaagactg ctgaatcggg tatttcttac atcaaaaata gattcatcac
     2341 catccacaat ggatacggat gaagaaattc tcaccgactg aacgttcagc cccgatagta
     2401 ttggggcttc agtatttatc gtcagcacaa cgtttctact ggcctgactg aaagagcgct
     2461 gcttacacaa tcgggcaaac tgtagtggtc aacaaagcct gtcatccata tgaaattgcg
     2521 ataaaatc
//
LOCUS       DAPHKZ010000252         2526 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.257, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000252 DAPHKZ010000000
VERSION     DAPHKZ010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2526
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.257"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..191
                     /gene="hemP"
                     /locus_tag="RH288_004608"
     CDS             <1..191
                     /gene="hemP"
                     /locus_tag="RH288_004608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HDV4033563.1"
                     /translation="RYTDSRKLTPETDANHKTASPQPIRRISSQTLLGPDGKLIIDHD
                     GQEYLLRKTQAGKLLLTK"
     gene            complement(195..1631)
                     /locus_tag="RH288_004609"
     CDS             complement(195..1631)
                     /locus_tag="RH288_004609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HDV4033564.1"
                     /translation="MTLSFITRWRDELPATYTTLSPTPLNNARLIWHNAELANTLGIP
                     SSLFKNGAGVWGGETLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQRLADGTTM
                     DWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
                     TVEPGAMLMRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWSHLADDEDKYRLW
                     FTDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSD
                     HQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLG
                     FMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDW
                     FARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEAL
                     RNPFSDRDDDYVSRPPDWGKRLEVSCSS"
     gene            complement(1694..2407)
                     /gene="ydiV"
                     /locus_tag="RH288_004610"
     CDS             complement(1694..2407)
                     /gene="ydiV"
                     /locus_tag="RH288_004610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor"
                     /protein_id="HDV4033565.1"
                     /translation="MKIFLENLYHSDCYFLPIRDNQQVLVGVELITHFSSEDGTVRIP
                     TSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLERDNYAG
                     ELLKYPFIELLINENYPHLNEGKDNRGLLSLSQVYPLVLGNLGAGNSTMKAVFDGLFT
                     RVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTAEILAQITPFDFHAL
                     QGCLWPAVPVNQITTLVQR"
BASE COUNT          683 a          652 c          584 g          607 t
ORIGIN      
        1 tgcgttatac ggatagcaga aaactcacgc ctgaaacgga tgccaatcac aagaccgctt
       61 ccccgcagcc tattcggcga atttccagcc agacactgtt aggtccggat ggcaaactga
      121 ttatcgatca tgacgggcaa gaatatctgc tccgtaaaac tcaggctggc aagctgctgt
      181 tgaccaagta gcctttaact cgagcagctg acttccagcc gtttacccca gtcaggtgga
      241 cgactgacat agtcatcatc tctgtcgctg aaaggatttc gcaacgcctc atgcaggcgg
      301 tgcaattccg tcatatcacc cttttctgcc gcttcaatcg cccgttgcgc caaccagttg
      361 cgcaatacca gagcggggtt aacgctttgc atcagttgct gacgctcact atcgctaacc
      421 tcgtcttgtt gcaaacgccc ccgataacgg gcaaaccagt catcaaatgc cgcacgatca
      481 ataaactcat cacgtagcgg tgacgccgcg ctgtgctgct cggtcagact cagcatgcgg
      541 aatgtgcggg tataatcgct gcgctctcgc gccatcagac tgaataattc attcagtagc
      601 gcgttatcct ctttttgctc cgtcatgaag cccagtttct gccgcatccg ttgtccataa
      661 tgcgtcaaca aaacctgctg atagctgtcc agggcctcat tcagggcatc tacggcaaca
      721 aatggtgaca atgtctgcgc cagacgctgt aaattccaca atgcgacggc aggttgattg
      781 tcaaagctgt aacgcccttg gtgatccgag tgattacaaa taaaaccggg ttcgtaatca
      841 tcaagaaaac caaacggccc gtaatcaagc gtcagcccca gcagcgacat gttgtcggta
      901 ttcatcaccc catgagcaaa gccgaccgtc tgccattggg caattaacga tgcggtacgt
      961 gcgacaacat cggtaaacca gagacggtat ttgtcctcat catctgcaag atgtgaccag
     1021 taatgacgaa tggcaaagtc agctaactga cgaacctttt ccggctcgcg gcgatagtaa
     1081 aaatgttcga aatgaccaaa gcgcagatga cttggtgcca cacgcatcag catcgcgcct
     1141 ggctccaccg tttcccgata cactggcgaa tcgctggtga cgatacttaa agcgcgggtc
     1201 gtcggaatgc ccagataatg catcgcctca ctggcgagac tttctcgtat cgtcgaacgt
     1261 aaaaccgccc gtccatcacc cattcgcgaa taaggcgtca ggccagcacc tttcagatgc
     1321 cagtccattg tagtgccatc agcaagccgt tgttcgccga gtaaaatgcc gcgcccatca
     1381 cccagttggc ccgcccagac gccgaactga tgaccactgt aaacctgcgc cagtggtgac
     1441 ataccaggca gtagggtttc gccaccccag acacctgcgc catttttaaa cagtgacgat
     1501 ggaataccca gcgtgttagc cagttcggca ttatgccaaa tcagccgggc attatttaaa
     1561 ggcgtagggg aaagtgttgt ataggttgct ggcaattcat cgcgccaacg ggtaataaaa
     1621 gacagggtca tagatcctcc tgtttgatag tgtagacggt tactctcgtc ttaaacacca
     1681 gcaaacagga gggttatcgc tgaaccaacg tcgttatctg atttacagga acggcaggcc
     1741 acaggcatcc ctggagagca tggaaatcga agggggtaat ctgtgccaat atttctgccg
     1801 tatcaatgcc tcccgcaatg atgcaattgc aacaagggga aatttgcgcc tggatcgcac
     1861 gaataaacgg ttcgaaggag cggtgcgtga tttgttgctg aataaaactt ttatccagca
     1921 tgacgcgggt gaaaagacca tcaaaaaccg ctttcattgt gctattgcct gctcccaaat
     1981 tacctaacac aaggggatac acttgcgata aggataaaag accgcgatta tcttttcctt
     2041 cattgagatg cgggtaattc tcattaatca acagttcaat aaacggatat tttaatagtt
     2101 cgcctgcgta attatccctc tctaataata atgtagccac ttgtggcgtt aaattaagcc
     2161 aggcaaagag tttatgttga ataaaaaaat gttggcatga ttttagtaat tccaactgct
     2221 ctgaaaataa ttgccaatgt tgctcctcgg taagttgcgc tataacccga ctcgtcggga
     2281 tacgcaccgt gccatcttca ctggagaaat gggtaattaa ctcaacgccg acaaggactt
     2341 gctggttgtc tcttatcggc aggaaatagc aatcagaatg ataaagattc tccaaaaaaa
     2401 tcttcatggt aaccgtccct ctcgaaggat gtttttcagt atccggctaa aagggatgag
     2461 gccataagac ataacaatta cagaaggagt aactttcatt tgttccatgt taaccacttt
     2521 ttcagg
//
LOCUS       DAPHKZ010000253         2497 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.258, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000253 DAPHKZ010000000
VERSION     DAPHKZ010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2497
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.258"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            170..1150
                     /locus_tag="RH288_004611"
     CDS             170..1150
                     /locus_tag="RH288_004611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HDV4033566.1"
                     /translation="MKIFIDDGSTNIKLAWLEDGDVKTLISPNSFKPEWSFSLLDDAA
                     PANYEIDGEKFSFDPLSADAVVTTETRYQYSDVNVVAIQHALQQTGLKAQPVDVIVTL
                     PISEYLDANNQKNKQNIERKKKNVMREVRVQGSDAFVIRSVSVLPESIPAGFSVLAGL
                     EDDESLLIVDLGGTTLDVSHVRSKMTGITKTWCDPNIGVSLITSGVKEQMAVHANTRV
                     SSFQADNIIVHRNEPDYLSRRIYNAEQRESIINVINERQKLLIKRVNDVISRFTDYTH
                     VMCVGGGAEIVAEAVKNLTKVPDERFYLSSSPQFDLVMGMIKMKGGVTNE"
     gene            1143..1559
                     /locus_tag="RH288_004612"
     CDS             1143..1559
                     /locus_tag="RH288_004612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HDV4033567.1"
                     /translation="MSDENKSRRCSFELFPDERTGDKIADELIANEKLKERGRFMRAM
                     LVTGAAFAAIDKRLPLLISELLTENTTLDDINKVISSVIPGAFSVEKKLLELLEKQSG
                     LHTSVDCSTPLTEQSLSRNDGEDQTRRNAENMFGDD"
     gene            complement(1561..>2497)
                     /gene="umuC"
                     /locus_tag="RH288_004613"
     CDS             complement(1561..>2497)
                     /gene="umuC"
                     /locus_tag="RH288_004613"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V subunit
                     UmuC"
                     /protein_id="HDV4033568.1"
                     /translation="ISPEFFGHQLREQVKSWTGLTMGVGIAPTKTLAKSAQWATKQWP
                     QFSGVVALTAENRNRILKLLGLQPVGEVWGVGHRLTEKLNALGINTALQLAQTNTAFI
                     RKNFSVILERTVRELNGESCISLEEAPPAKQQIVCSRSFGERITDKDAMHQAVVQYAE
                     RAAEKLRGERQYCRQVTTFVRTSPFAVKEPCYSNAAVEKLPLPTQDSRDIIAAACRAL
                     NHVWREGYRYMKAGVMLADFTPSGIAQPGLFDEIQPRKNSEKLMKTLDELNQSGKGKV
                     WFAGRGTAPEWQMKREMLSQCYTTKWRDIPLARLG"
BASE COUNT          626 a          552 c          596 g          723 t
ORIGIN      
        1 gatttcctct ggtcttaaag ttgtgtgtac aatgtacatg caatttatcg tgtttttatg
       61 ttgcatttgt cctttcaaaa agaccgtttt ttcattataa ttgaatatac attgcatgta
      121 tgaagtatgt ttgttttttc tatttgttta tgagcaacgg agactggtta tgaaaatctt
      181 tattgatgat ggttctacca acattaaact tgcctggttg gaggatggtg acgtgaaaac
      241 gttaatcagc cctaacagct ttaaaccgga atggtctttt agtttactgg atgatgctgc
      301 tccggctaat tacgagatcg acggcgagaa gttttcattt gatccattaa gtgctgatgc
      361 tgtcgtaacg actgaaacac gctatcagta cagtgatgtg aatgttgtgg ccattcagca
      421 tgcgctacag cagaccggcc tgaaagcgca gcctgttgat gtcatcgtca cattgccgat
      481 ctctgaatac cttgacgcca acaatcagaa aaataagcaa aacattgaaa gaaagaaaaa
      541 aaatgtgatg cgtgaagtac gggtgcaggg gagtgatgca tttgttattc gcagtgtttc
      601 cgttcttcct gaaagtattc ccgctggttt cagtgttctt gcggggcttg aggatgatga
      661 atcccttttg atcgtagatc tcggtggtac aactcttgat gtgtcgcatg ttcgtagcaa
      721 aatgacaggg attacaaaaa cctggtgtga tccgaatatc ggcgtgtccc tgattacatc
      781 cggggttaag gaacagatgg ctgtacatgc taatacaaga gtgagctcat tccaggctga
      841 caatatcatt gtgcaccgta atgaacctga ctacctttcc cgtcgcattt ataatgctga
      901 acagcgtgag tctatcatta atgttatcaa tgaacggcag aagttgctta ttaaacgagt
      961 taatgatgtc atcagccgtt tcaccgacta tacacatgta atgtgtgttg gtggtggggc
     1021 tgaaattgtg gccgaggctg tgaagaacct gactaaggtt cctgatgagc gcttttatct
     1081 gagctcatcc ccgcagtttg atttagtcat gggaatgata aaaatgaaag gtggtgtgac
     1141 taatgagtga tgaaaataaa tccagacgct gctcatttga acttttcccg gatgaacgga
     1201 caggagataa gatagcagat gagctcattg caaatgaaaa actgaaggag cggggacgtt
     1261 tcatgcgcgc gatgttagtt actggtgcgg cgtttgcagc tatagataaa cgtcttcctt
     1321 tgctgatatc ggagttactg acagaaaata cgactctgga tgatattaat aaggtgattt
     1381 ccagcgtaat accaggtgct ttttcggttg aaaagaaatt gcttgaatta ctggaaaaac
     1441 aatctggtct ccatacgtct gtggattgca gtactcctct tacagagcag agtctgtcga
     1501 gaaatgacgg tgaagaccag accagaagaa acgctgaaaa tatgttcgga gatgactgaa
     1561 ctaacccagc ctggccaggg gaatatctcg ccatttagtt gtataacact gactcaacat
     1621 ttcccgtttc atttgccatt caggggcggt tcctcgcccc gcaaaccaca ctttcccttt
     1681 tcccgactgg ttcagttcat cgagtgtttt cattaacttt tcactgtttt tacggggctg
     1741 gatttcatca aataatcccg gctgcgctat acccgatggt gtgaaatcag ccagcatgac
     1801 acctgccttc atatagcggt acccttcacg ccagacatgg tttaaggctc tgcatgcggc
     1861 ggcaataatg tcccggctgt cctgtgtggg caatggaagc ttttccacag cggcattgct
     1921 gtaacagggt tcttttactg caaagggtga tgtccgtaca aatgtcgtca cctgccggca
     1981 atactgacgc tccccacgta gtttctctgc ggcccgctct gcatactgaa caacagcctg
     2041 gtgcatggca tctttgtctg tgattcgttc accaaaactg cgactacaga caatctgctg
     2101 ttttgccggt ggtgcttctt ccagggatat gcaggactcg ccgttgagtt cgcgtaccgt
     2161 acgctcaaga atgacgctga agtttttccg gatgaatgcc gtgttagtct gcgccagctg
     2221 cagtgctgtg ttaataccca gcgcattcag cttttccgtc agtctgtgtc ctactcccca
     2281 gacctcacca actggctgca gccccagtag cttcaagatc cgattacggt tttctgccgt
     2341 cagcgcgacc actccggaaa actgtggcca ttgctttgtt gcccactgtg cacttttagc
     2401 cagcgttttt gtaggcgcaa tgcccacccc catggtgagt cctgtccagc tctttacctg
     2461 ttccctgagc tgatgaccaa aaaactccgg agagatg
//
LOCUS       DAPHKZ010000254         2490 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.259, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000254 DAPHKZ010000000
VERSION     DAPHKZ010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2490
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.259"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(176..2443)
                     /gene="adiA"
                     /locus_tag="RH288_004614"
     CDS             complement(176..2443)
                     /gene="adiA"
                     /locus_tag="RH288_004614"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418541.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HDV4033569.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     FAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQ
                     DLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQD
                     CWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPD
                     TYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPVAEVTPREAYNAIVDNNVELVSI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEG
                     TEIIDGIYHVMCVKA"
BASE COUNT          574 a          609 c          680 g          627 t
ORIGIN      
        1 gtacatattt ttttacagga taaataacag gcaaaaaaag cgcggggtgg ggccgcgcaa
       61 aaagtatgac atttttgttt gcagcaattt ttatgaaaac gttgccatac tcaaaaggcc
      121 taaggccagg cggcgtaatg ttatttaaac aattacgcct tcagcggaat agtggttacg
      181 ctttcacgca cataacgtgg taaataccgt caataatttc agtcccttca gtttcgtgtt
      241 caaatccagg gaaatggtgg tcccaggatt gcagcgagcg taaataactt acttgcggac
      301 tgtttttatc gccgaagttt tcaccagaca gcagcatcgg gattcctggc ggatacggga
      361 taactgagtt tgccgcgatg cgtcctggca gattttcaat ggataccagt tcgacattgt
      421 tgtcgacaat cgcgttgtac gcttcacgcg gggtgacttc cgccaccggc aggccggaat
      481 aggcttcgtt caaccgtgcg ccagggttgt tttctttcag ccaggcaaac atggtgtcac
      541 ccagatcgtg aatccccatg ttcgcgtaag tgtcaggata ttgttcaaca agttccggca
      601 tcacctgcgc cagcggtgtg ttggcgtcat agtggcgttt gaaggagcaa agggtgttaa
      661 ccagagttcc ccatttccca cgggttacgc ccatagagaa caggaacata atttggaagt
      721 cagtggtgcg ggtaggtaca atgccgtggc gaccaagcca ggcagtgacc agcgccgccg
      781 gaacaccggt ttcttccagt tcaccatctt cacccattcc cggagcaagg atgctgactt
      841 taatcgggtc gagcatactc cagttatccg gaatatcttt gaagccgtgc cagctttcgc
      901 ccggatgcat tacccagcag tcctgaacgg tggtcagcag tttggttggt gcgtcagcaa
      961 agtcataggt tttgccggtt tgtgggtcgg tgacgacttc tttgttccac ggtttgaaga
     1021 accagctacc gtcagcggtg aactctttat atagccgcgc catcgcctga cggaaatcaa
     1081 ccgcttcgtc aatcacttcc tgtgtcagtg acaggccgct gttgccgtcc atcatcgaca
     1141 ccgccacgtc gttggatgcg cagatggcat acagcgggga ggtggtggca tgcatcatgt
     1201 aggcctggtt gaagcgggag aagttaatcg ccccacgacc ttcacgtaca tgaatataag
     1261 aagcctgtga cagcgcattc agcagtttgt gggtggagtg ggtggcgaaa acggtaggac
     1321 cgttgtgatc gccaggttcg ccgcgcatgg catagtgatc ggcatagatc gggttgaaac
     1381 gtgcatagcc gtaccaggct tcgtcaaagt gcagacgatc ggaggttttt tccagcagat
     1441 cctgcgcttc tttagcgtta taacacacgc cgtcataggt gcagttggtc accacgcagt
     1501 aagacggttt ttgcccggct ttgtctttgg tcagcgggct ttcactgatt ttcttctgca
     1561 aggtttcagg ttgcatttcc tgcggataga ttggcccgat aatgccgtag cggttgcggc
     1621 ttggcaccat atagaccggt ttcgcgcctg tcagcatcaa accttgttcg atggatttat
     1681 ggcagttacg gtcaacgacc acgacatcgt tatcggtcat gcaagcctgc atgatggtgc
     1741 ggttagagcc ggaagtaccg acgactaccg accaggagcg atcggcacca aatacgcgtg
     1801 cggcatattt ttcgctttcg ccaaatgcgc cagtatggtc aagcaaagaa ccgagggaag
     1861 ttcgttcgat gcccatgtcg gtgcggaaca gattttcacc atagtagtca tggtagaaac
     1921 gtccggcggg tgttttggta aaaccaacgc cgccctggtg gcctggcgct gcccaggaat
     1981 attcatggat gtcactatat ttcatcagcg cgctgaacag tggcggcaac agctgctggc
     2041 ggtagcgggt catcgcggca acggcgcgtc cggcgataaa gtcggcggta tcttccagaa
     2101 tccaggcgaa ttcatcgaca agctccagca ggtcgcgatc cattgcggcg agggcttttt
     2161 cccgatcgcc caacaggaag accggcacgt tttgttggcg ctcatgaagc ttaccgatca
     2221 attgtctgac gttttgatgt tcgtccggat gttccatttg atagctgaac atcaggcagt
     2281 caatggcttc gtttgaagag agaatggcaa aaccatcatc aaaggaggtg gatttaatca
     2341 cggtaacatt ttgctggctt aaagcatctg ccagacgctc aacggcgtta ccgacccagg
     2401 tgtcttgatg gagaaactcg ctttcaacaa ttaatacttt catcattgct tacccggtta
     2461 tgaaggaatc ttcgttgcgg gcaagtatct
//
LOCUS       DAPHKZ010000255         2409 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.260, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000255 DAPHKZ010000000
VERSION     DAPHKZ010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2409
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.260"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            144..1808
                     /gene="asnB"
                     /locus_tag="RH288_004615"
     CDS             144..1808
                     /gene="asnB"
                     /locus_tag="RH288_004615"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HDV4033570.1"
                     /translation="MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNA
                     ILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEV
                     ILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
                     EMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALED
                     SVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLP
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFEAYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPL
                     PSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK"
     gene            2188..2264
                     /locus_tag="RH288_004616"
     tRNA            2188..2264
                     /locus_tag="RH288_004616"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2222..2224,aa:Met,seq:cat)
     gene            2274..2358
                     /locus_tag="RH288_004617"
     tRNA            2274..2358
                     /locus_tag="RH288_004617"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2308..2310,aa:Leu,seq:tag)
BASE COUNT          622 a          588 c          619 g          580 t
ORIGIN      
        1 agaccttttt tcaccaatcg acaatcacca ttacgttttt tattttttca ccgccaaatc
       61 gcttgcgcac agtgctgctt tgcggcattt ttttaaacaa gcaaacacaa caagcaacaa
      121 ataccaggtt aacggagaag gttatgtgtt caatttttgg cgtattcgat atcaaaacag
      181 acgcagttga gctgcgtaag aaagccctcg agctgtcacg cctgatgcgt catcgtggcc
      241 cggactggtc cggtatttat gccagcgata acgccattct cgcccacgaa cgtctgtcaa
      301 ttgttgacgt taacgcgggg gcgcaacctc tctacaacca acaaaaaacc cacgtactgg
      361 cggtaaacgg tgaaatctac aaccaccagg cattgcgcgc cgaatatggc gatcgttacc
      421 agttccagac cgggtctgac tgtgaagtga tcctcgcgct gtatcaggaa aaagggccgg
      481 aatttctcga cgacttgcag ggcatgtttg cctttgcact gtacgacagc gaaaaagatg
      541 cctacctgat tggtcgcgac catctgggga tcatcccact gtatatgggg tatgacgaac
      601 acggtcagct gtatgtggcc tcagaaatga aagcgctggt gccagtttgc cgcacgatta
      661 aagagttccc ggcggggagc tatttgtgga gccaggacgg cgaaatccgt tcttactatc
      721 atcgcgactg gttcgactac gatgcggtga aagataacgt gaccgacaaa aacgagctgc
      781 gtcaggcact ggaagattca gttaaaagcc atctgatgtc tgatgtgcct tacggtgtgc
      841 tgctttctgg tggtctggat tcctcaatta tttccgctat caccaagaaa tacgcagccc
      901 gtcgcgtgga agatcaggaa cgctctgaag cctggtggcc gcagttacac tcctttgctg
      961 taggtctgcc gggttcaccg gatctgaaag cagcccagga agtggcaaac catctgggca
     1021 cggtgcatca cgaaattcac ttcactgtac aggaaggtct ggatgccatc cgcgacgtga
     1081 tttaccacat cgaaacttat gatgtgacca ctattcgcgc ttcaacaccg atgtatttaa
     1141 tgtcgcgtaa gatcaaggcg atgggcatta aaatggtgct gtccggtgaa ggttctgatg
     1201 aagtgttcgg cggttatctt tacttccaca aagcaccgaa tgccaaagaa ctgcatgaag
     1261 agacggtgcg taaactgctg gccctgcata tgtatgactg cgcgcgtgcc aacaaagcga
     1321 tgtcagcctg gggcgtggaa gcacgcgttc cgttcctcga caaaaaattc cttgatgtgg
     1381 cgatgcgtat taacccacag gataaaatgt gcggtaacgg caaaatggaa aaacacatcc
     1441 tgcgtgaatg ttttgaagcg tatctgcctg caagcgtggc ctggcggcag aaagagcagt
     1501 tctccgatgg cgtcggttac agttggatcg acaccctgaa agaagtggct gcgcagcagg
     1561 tttctgatca gcaactggaa actgcccgct tccgcttccc gtacaacacg ccaacctcta
     1621 aagaagcgta cttgtatcgg gagatctttg aagaactatt cccgcttcct agcgccgctg
     1681 agtgcgtgcc gggcggtcct tccgtcgctt gttcttccgc taaagcgatc gaatgggatg
     1741 aagcgttcaa gaaaatggac gatccgtctg gtcgcgcggt tggtgttcac cagtcggcgt
     1801 ataagtaaga aatgcgaaac agccccggtg aaatccgggg ctgtttcagt tattgaggtg
     1861 cttgttgatt ctgatatgca gtaaggaaat gttccgggtt tgccacatca ctgtttgaca
     1921 actcatcact gtaggccagt atttcataga ttaatttccc accactattg ttaaattccg
     1981 aatttcatcc tgtatgacaa aagaatggct gtagggtggg aaaaaacaca aagtaaacaa
     2041 taattgacga atatagcgcc acgctgttcg caacctaacc aaacagtcac tttcgagcaa
     2101 ttttccttga aaaagaggtt gacgctgcaa ggctctatac gcataatgcg ccccgcaacg
     2161 ccgataaggt atcgcgaaaa aaaagatggc tacgtagctc agttggttag agcacatcac
     2221 tcataatgat ggggtcacag gttcgaatcc cgtcgtagcc accatctttt tttgcgggag
     2281 tggcgaaatt ggtagacgca ccagatttag gttctggcgc cgcaaggtgt gcgagttcaa
     2341 gtctcgcctc ccgcaccatt caccagaaag cgttgtacgg atggggtatc gccaagcggt
     2401 aaggcaccg
//
LOCUS       DAPHKZ010000256         2393 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.261, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000256 DAPHKZ010000000
VERSION     DAPHKZ010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2393
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.261"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            236..493
                     /gene="repA"
                     /locus_tag="RH288_004618"
     CDS             236..493
                     /gene="repA"
                     /locus_tag="RH288_004618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HDV4033571.1"
                     /translation="MSQTENAVTSSSGTKRTYRKGNPVPARERQRASLARRSNTHKAF
                     HAVIQARLKDRLSELADEEGITQAQMLEKLIESELKRRATS"
     gene            725..799
                     /gene="tap"
                     /locus_tag="RH288_004619"
     CDS             725..799
                     /gene="tap"
                     /locus_tag="RH288_004619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001442103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HDV4033572.1"
                     /translation="MPGKVQDFFLCSLLLCIVSAGWCG"
     gene            792..1274
                     /locus_tag="RH288_004620"
     CDS             792..1274
                     /locus_tag="RH288_004620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033573.1"
                     /translation="MANHETHSVIAGGIESDLHIDSSKYPHPFCSLLQKRAHFDSFKH
                     LIFIRGLLAIAHGKRKNKISASMVSFYVSLVQVMCAHYIPDTNKVNLSVKELSVCSGG
                     SYTRVWRALKTLDNDLHLIAFDGGTIWFRPDMFETLRVGPDELVTARRRGNSVGGGHG
                     "
     gene            1267..2124
                     /gene="repA"
                     /locus_tag="RH288_004621"
     CDS             1267..2124
                     /gene="repA"
                     /locus_tag="RH288_004621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HDV4033574.1"
                     /translation="MADLLQKYYSQVKNPNPVFTPREGARTLKFCEKLMEKAVGFTSR
                     FDFAIHVAHARSKGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECG
                     LATESAAGKLSITRASRALTFLAELGLITYQTEYDPLIGCYIPTDITFTPALFAALDV
                     SEDAVVAARRSRVEWENRQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIK
                     RARARRDANRERQDIVTLVKRQLTREISEGRFTANREAVKREVERRVKERMILSRNRN
                     YSRLATASP"
BASE COUNT          614 a          597 c          604 g          578 t
ORIGIN      
        1 ttcaggggca gacaccctat ataccagaaa cagccggtcc cgcccggggc cggcaccctg
       61 gctaaggcat ttccagcttt tcagtcattt cattatcaaa atcacattaa acggtcgtaa
      121 tcagacatga tttgtgcgcc aacacagatc atcgtcacaa ctttcaagtc gctgatttca
      181 aaaaactgta gtattctctg cgaaacgatc cctgtttgag aattgaggag gcgagatgtc
      241 gcagacagaa aatgcagtga cttcctcatc aggcaccaag cgtacatacc ggaaaggtaa
      301 ccctgttccg gccagagaga ggcaaagagc ttctctggct cgcagaagca acactcataa
      361 ggcttttcat gcggttattc aggcccggtt aaaagacagg ctgagtgaac tggcggatga
      421 ggaaggtatt actcaggcgc agatgcttga aaaactgatt gaatcagagc tgaaacgcag
      481 agcgacttcg taaatattca cattcttgct tatctcagga gtgagtggta gattgctgat
      541 cgtttaagga attttgtggc tggccacgcc gtaaggtggc agggaactgg ttctgatgtg
      601 gatttacagg agccagaaaa gcgaaaaccc cgataatctt cttcaagttt ggcgactaga
      661 aagattaccg gggccccata aaaccgcata gccaacaatt cagctatgcg gggagtatag
      721 ttatatgccc ggaaaagttc aagacttctt tctgtgctca ctccttctgt gcattgtaag
      781 tgcaggatgg tgtggctaat catgaaacac attcagtaat agcgggtggg attgaatcag
      841 atcttcacat tgattccagc aagtatcctc acccgttttg cagccttctc cagaaaaggg
      901 ctcattttga ctccttcaag catctgatct tcatcagagg tttgcttgca atagcgcatg
      961 gcaaacgtaa aaataaaatc agcgcgtcga tggttagttt ttatgtttcc ctcgtacaag
     1021 taatgtgcgc acactacatc cctgatacga acaaagttaa cttatctgtt aaagagcttt
     1081 cagtttgtag tggaggttca tacactcgtg tttggagagc cctcaaaact cttgataatg
     1141 atcttcatct catcgctttt gatggaggaa ccatctggtt cagaccagat atgttcgaaa
     1201 ctttacgtgt cggcccagac gagctagtta ccgcccgtag gagggggaat agtgttggag
     1261 ggggacatgg ctgatctcct tcaaaaatac tattcacagg ttaaaaatcc gaatccggtg
     1321 ttcacacccc gtgaaggtgc cagaacgctg aagttctgcg aaaaactgat ggaaaaggcg
     1381 gtgggcttca cctcccgttt tgatttcgcc attcatgtgg cacatgcccg ttcgaaggga
     1441 ctgcgtcggc gcatgccacc ggtactgcgt cgccgggcta ttgatgcgct gctgcagggg
     1501 ctgtgttttc actatgaccc gctggccaac cgcgtccagt gctccatcac tacgctggcc
     1561 attgagtgcg gactggcgac ggagtctgct gccggaaaac tctccatcac ccgggcctcc
     1621 cgagccttga cgttccttgc agagctggga ctgattacct accagacgga atatgatccg
     1681 cttatcgggt gctacattcc gaccgatatc acgttcacac cggcgttatt tgccgccctt
     1741 gatgtgtctg aggatgcagt ggttgctgcg cgccgcagtc gtgttgaatg ggaaaacaga
     1801 cagcgcaaaa agcaggggct ggataccctg ggtatggatg aactgatagc gaaagcctgg
     1861 cgttttgtgc gtgagcgttt ccgcagttac cagacagagc ttaagtcccg tggaataaag
     1921 cgtgcccgtg cgcgtcgtga tgcgaacagg gaacgtcagg atatcgtcac cctggtgaaa
     1981 cggcagctga cgcgtgaaat ctcggaaggg cgcttcactg ccaatcgtga ggcggtaaaa
     2041 cgcgaagtgg agcgtcgtgt gaaagagcgc atgattctgt cacgtaaccg taattacagc
     2101 cggctggcca cagcttcccc ctgaaagtga cctcttctga ataatccggc ccgcaccgga
     2161 ggcattcgca cgcctgaagc ctgccagcga acaaaaaagc agcacctcat acaaaaaaca
     2221 acctcatcat ccaccttctg gtgcatctgg ccccccctgt ttttgataca aaacacgcct
     2281 cacagacggg gaattttgct tatccacatt taactgcaat ggacttcccc ataaggttac
     2341 aaccgttcat gtcataaagc gccatccgcc agccttacag ggtgcaatgt atc
//
LOCUS       DAPHKZ010000257         2366 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.262, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000257 DAPHKZ010000000
VERSION     DAPHKZ010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2366
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.262"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..231
                     /locus_tag="RH288_004622"
     CDS             <1..231
                     /locus_tag="RH288_004622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4033575.1"
                     /translation="DTWQAELHIEVFLPAQVPDSELDSWMESRIYPVMSDVPALSDLI
                     TSMVASGYDYRRDDDAGLWSSADLTYVITYEM"
     gene            239..979
                     /locus_tag="RH288_004623"
     CDS             239..979
                     /locus_tag="RH288_004623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4033576.1"
                     /translation="MPVPNPVMPVKGAGTTLWVYKGNGDPYANPLSDVDWSRLAKVKD
                     LTPGELTAESYDDSYLDDEDADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNE
                     GDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTA
                     ATGMTVTPASTSVVKGQSTTLTVAFQPEGVTDKSFRAVSADKTKATVSVSGMTITVNG
                     VAAGKVNIPVVSGNGEFAAVAEITVTAS"
     gene            995..1417
                     /locus_tag="RH288_004624"
     CDS             995..1417
                     /locus_tag="RH288_004624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HDV4033577.1"
                     /translation="MFLKTESFEHNGVTVTLSELSALQRIEHLALMKRQAEQAESDSN
                     RKFTVEDAIRTGAFLVAMSLWHNHPQKTQMPSMNEAVKQIEQEVLTTWPTEAISHAEN
                     VVYRLSGMYEFVVNNAPEQTEDAGPAEPVSAGKCSTVS"
     gene            1399..1833
                     /locus_tag="RH288_004625"
     CDS             1399..1833
                     /locus_tag="RH288_004625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HDV4033578.1"
                     /translation="MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHY
                     FHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLNRREADEEPEDDVLMQKAAGLAG
                     GVRFGPDGNEVIPASPDVADMTEDDVMLMTVSEGIAGGVRYG"
     gene            1826..>2366
                     /locus_tag="RH288_004626"
     CDS             1826..>2366
                     /locus_tag="RH288_004626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail length tape measure family protein"
                     /protein_id="HDV4033579.1"
                     /translation="MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTESDAKKTAAVV
                     EQSLSRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQS
                     GLTADRMLVLSRAGQAAGLT"
BASE COUNT          513 a          600 c          756 g          497 t
ORIGIN      
        1 gatacctggc aggcggagct gcatattgaa gttttcctgc ctgctcaggt gccggattca
       61 gagctggatt cgtggatgga gtcccggatt tatccggtga tgagcgatgt cccggcactg
      121 tcagatttga tcaccagtat ggtggccagt ggctatgact accggcgcga cgatgatgcg
      181 ggcctgtgga gttcagccga tctgacttat gtcattacct atgaaatgtg aggacgatat
      241 gcctgtacca aatccagtaa tgccggtgaa aggggccggg accacactgt gggtttataa
      301 ggggaacggt gacccttatg cgaacccgct ttcagacgtt gactggtcgc gtctggctaa
      361 agttaaagac ctgacgcccg gcgaactgac cgctgagtcc tatgacgaca gctatctcga
      421 tgatgaagat gcggactgga ctgcgaccgg gcaggggcag aaatctgccg gagataccag
      481 cttcacgctg gcgtggatgc ccggagagca ggggcagcag gcgctgctgg cgtggtttaa
      541 tgaaggcgat acccgtgcct ataaaatccg cttcccgaac ggcacggtcg atgtgttccg
      601 cggctgggtc agcagtatcg gtaaggcggt gacggcgaag gaagtgatca cccgcacggt
      661 gaaagtcacc aatgtgggac gtccgtcgat ggcagaagat cgcagcacgg taacagcggc
      721 aaccggcatg accgtgacgc ctgccagcac ctcggtggtg aaagggcaga gcaccacgct
      781 gaccgtggcc ttccagccgg agggcgtaac cgacaagagc tttcgtgcgg tgtctgcgga
      841 taaaacaaaa gccaccgtgt cggtcagtgg tatgaccatc accgtgaacg gcgttgctgc
      901 aggcaaggtc aacattccgg ttgtatccgg taatggtgag tttgctgcgg ttgcagaaat
      961 taccgtcacc gccagttaat ccggagagtc agcgatgttc ctgaaaaccg aatcatttga
     1021 acataacggt gtgaccgtca cgctttctga actgtcagcc ctgcagcgca ttgagcatct
     1081 cgccctgatg aaacggcagg cagaacaggc ggagtcagac agcaaccgga agtttactgt
     1141 ggaagacgcc atcagaaccg gcgcgtttct ggtggcgatg tccctgtggc ataaccatcc
     1201 gcagaagacg cagatgccgt ccatgaatga agccgttaaa cagattgagc aggaagtgct
     1261 taccacctgg cccacggagg caatttctca tgctgaaaac gtggtgtacc ggctgtctgg
     1321 tatgtatgag tttgtggtga ataatgcccc tgaacagaca gaggacgccg ggcccgcaga
     1381 gcctgtttct gcgggaaagt gttcgacggt gagctgagtt ttgccctgaa actggcgcgt
     1441 gagatggggc gacccgactg gcgtgccatg cttgccggga tgtcatccac ggagtatgcc
     1501 gactggcacc gcttttacag tacccattat tttcatgatg ttctgctgga tatgcacttt
     1561 tccgggctga cgtacaccgt gctcagcctg tttttcagcg atccggatat gcatccgctg
     1621 gatttcagtc tgctgaaccg gcgcgaggct gacgaagagc ctgaagatga tgtgctgatg
     1681 cagaaagcgg cagggcttgc cggaggtgtc cgctttggcc cggacgggaa tgaagttatc
     1741 cccgcttccc cggatgtggc ggacatgacg gaggatgacg taatgctgat gacagtatca
     1801 gaagggatcg caggaggagt ccggtatggc tgaaccggta ggcgatctgg tcgttgattt
     1861 aagtctggat gcggccagat ttgacgagca gatggccaga gtcaggcgtc atttttccgg
     1921 tacggaaagt gatgcgaaaa aaacagcggc agtcgttgaa cagtcgctga gccggcaggc
     1981 gctggctgca cagaaagcgg ggatttccgt cgggcagtat aaagccgcca tgcgtatgct
     2041 tcctgcacag ttcaccgacg tggccacgca gcttgcaggc gggcaaagtc cgtggctgat
     2101 cctgctgcaa cagggtggtc aggttaagga ctccttcggc gggatgatcc ccatgttcag
     2161 ggggcttgcc ggtgcaatca ccctgccgat ggtcggggcc acctcgctgg cggtggcgac
     2221 cggtgcgctg gcgtatgcct ggtatcaggg caactcaacc ctgtccgatt tcaacaaaac
     2281 gctggtcctt tccggcaatc agtcggggct gacggcagat cgtatgctgg tcctgtccag
     2341 agccgggcag gcggcagggc tgacgt
//
LOCUS       DAPHKZ010000258         2366 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.263, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000258 DAPHKZ010000000
VERSION     DAPHKZ010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2366
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.263"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            99..410
                     /locus_tag="RH288_004627"
     CDS             99..410
                     /locus_tag="RH288_004627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033580.1"
                     /translation="MKYDGDGRATARFFSDKGCRRAPLFTAPADAARQERCLWSVSRV
                     RRARDGRFYCSRLVPVTVYASLSPFSDERPSSRFRGIFSPSKRRRLRYSTVGLTRYRT
                     R"
     gene            487..1170
                     /locus_tag="RH288_004628"
     CDS             487..1170
                     /locus_tag="RH288_004628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HDV4033581.1"
                     /translation="MSRFVLGNCIDVMTRIPDNAIDFILTDPPYLVGFRDRSGRTIAG
                     DKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFIAAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYILAKGRPRLPQNPPPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DDWFMPEAA"
     gene            1171..1392
                     /locus_tag="RH288_004629"
     CDS             1171..1392
                     /locus_tag="RH288_004629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033582.1"
                     /translation="MNYAGHEKLRAEVAEVANAMCDLRTTMNEMERRYSFNADTLPER
                     LVRQTLFRANRLLMEAYTEILELDACFKD"
     gene            1406..1840
                     /locus_tag="RH288_004630"
     CDS             1406..1840
                     /locus_tag="RH288_004630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HDV4033583.1"
                     /translation="MYGTCETLCRELAAKYPGYTPLMLVIWSPEEIQALADGMEISLT
                     DHEIRTVLARMEDIPEDQRTESGISSAAVMEIISNVSENRQVTVPAELLASLIQTAEQ
                     ALWKREWAARDNGLVVPECVTRRLAVVNQARALLKNNTREND"
     gene            1885..>2366
                     /locus_tag="RH288_004631"
     CDS             1885..>2366
                     /locus_tag="RH288_004631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033584.1"
                     /translation="MNETLNALICRHARNLLLAQGWPEETDVDQRNPNHPGWISIYVR
                     LDTPRLATLLINRHGGVLPPHLASAIQKLTGTGAELVLSGSQWQSLPVLPADGTQVSF
                     PYAGEWLAEDEIRAVLAAVRDAIRSICYQAADDARRIRAALTTTGQTLLTRQTRRFRL
                     V"
BASE COUNT          502 a          680 c          715 g          469 t
ORIGIN      
        1 tggggggaac tggaatgctc ttccccgaca gatgacgatg agctgccgga agtcaccgga
       61 cctgcgtgga tagtcgacaa tgtggcgcat tatggcggat gaagtatgac ggagacgggc
      121 gggcaaccgc ccgtttcttt tccgacaaag gatgtcgccg tgctcctctt tttactgcgc
      181 cggctgacgc ggcgcggcag gaacgctgcc tgtggtcagt gtcccgcgtc cggcgggcac
      241 gggacgggcg cttttactgc tcccggctgg taccggtgac agtgtacgcc agcctgtcgc
      301 ccttttctga tgaacgccct tcaagccgct ttcgcggcat attctcgccg tcaaaaagac
      361 gacggctgcg atattccacg gtcggcctga cccgttaccg gacgcggtga acagcccaca
      421 ggcagcgggg aacgggcacc acaggggtgc cctcccggtg ccctctgtaa gagaaggagc
      481 gttattatgt cccgttttgt tcttggtaac tgcatcgatg ttatgacgcg tatccctgat
      541 aacgccattg atttcatatt aactgacccg ccatatctcg tcggctttcg tgaccgttcc
      601 gggcgcacca tcgccggaga taaaaccgat gaatggctgc aaccggcctg taatgagatg
      661 taccgcgtgc tgaaaaaaga cgcgttaatg gtgagcttct atggctggaa ccgcgtcgat
      721 cgctttattg ccgcctggaa aaatgcggga ttcagcgttg ttggtcacct ggtcttcacc
      781 aaaaactaca catcgaaggc cgcatatgtg ggctatcgcc acgaatgcgc ctacatcctg
      841 gcaaaaggcc gtccacgtct gccacaaaac ccgccgccgg acgtgctggg ctggaaatat
      901 tcgggcaatc gccatcaccc gacggaaaag cccgttacca gcctgcaacc gctgattgag
      961 agcttcacac acccgaacgc aattgtgctg gacccgtttg caggcagcgg ctcaacctgc
     1021 gtcgccgccc tccagtccgg acgccggtat atcggtatcg agctgcttga gcagtatcac
     1081 cgtgccgggc agcaacgcct tgccgccgtg caacgggcca tgcagcaggg ggccgcgaat
     1141 gatgactggt ttatgccgga ggctgcgtaa atgaactatg ccggacacga aaaacttcgc
     1201 gccgaagtgg cggaggtggc caatgccatg tgcgacctgc gtacaaccat gaatgagatg
     1261 gagcggcggt acagctttaa tgctgacacc ctgccggaac gtctggtgcg tcagacgttg
     1321 tttcgcgcaa accgcctcct gatggaggca tataccgaaa ttctggaact ggatgcgtgc
     1381 tttaaagatt gagaaggaga cgagaatgta cggaacatgc gaaacgctct gccgggagct
     1441 ggcagcaaag tatccgggat acacgccgct gatgctggtt atctggtctc cggaagagat
     1501 tcaggcactg gctgacggta tggaaatttc tctgaccgat catgaaatca ggaccgtcct
     1561 ggcgcgcatg gaggacatcc cggaagacca gaggactgaa tccggtattt cttccgccgc
     1621 ggtgatggag attatcagca acgtgagcga aaaccgccag gtgaccgtcc ctgctgaact
     1681 gctggcgtcc ctgattcaga ccgctgaaca ggcactgtgg aaacgtgagt gggccgcccg
     1741 tgataacggc ctcgtcgtcc cggaatgcgt cacccgccga ctggcggtgg ttaatcaggc
     1801 ccgcgccctg ctgaaaaaca acacacgcga aaacgactga tgttatcgcc gcctgcgggc
     1861 ggcgattcag ggagaccatg aatcatgaac gaaacgctga atgcactgat ttgtcgccac
     1921 gcccgtaacc tgctgctggc gcagggctgg ccggaagaga cggatgttga ccagcgaaat
     1981 ccgaaccatc cgggctggat cagcatttac gtgcggctgg atacgccccg gctggcgacg
     2041 ttacttatca accgtcacgg cggcgtactg ccgccgcacc tggcctctgc cattcagaaa
     2101 ctgaccggaa ccggggcgga acttgttctg tccggcagtc agtggcagtc gctgccggta
     2161 cttccggcag acggaacgca ggtgtctttc ccgtatgccg gtgagtggct ggcagaagac
     2221 gaaatcaggg ctgtacttgc ggcggtgcgc gatgcaatac gaagcatctg ttaccaggcg
     2281 gcagacgatg cgcggcgtat ccgggcggcg ctgaccacca ccggtcagac gttgctgacc
     2341 cgccagacgc gccgctttcg tctggt
//
LOCUS       DAPHKZ010000259         2209 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.264, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000259 DAPHKZ010000000
VERSION     DAPHKZ010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2209
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.264"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            15..518
                     /locus_tag="RH288_004632"
     CDS             15..518
                     /locus_tag="RH288_004632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV4033585.1"
                     /translation="MNNIAPQSPVMRRLTQQDNPAIARVIRQVSAEYGLTADKGYTVA
                     DPNLDELYQVYSQPGHAYWVVEYDGEVVGGGGIAPLTGSESDICELQKMYFLPAIRGK
                     GLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIGLYEHLGFQHIDYALGCTGHVDCE
                     VRMLREL"
     gene            complement(564..980)
                     /gene="rraB"
                     /locus_tag="RH288_004633"
     CDS             complement(564..980)
                     /gene="rraB"
                     /locus_tag="RH288_004633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HDV4033586.1"
                     /translation="MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLE
                     TLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAE
                     KFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH"
     gene            1142..2146
                     /gene="argF"
                     /locus_tag="RH288_004634"
     CDS             1142..2146
                     /gene="argF"
                     /locus_tag="RH288_004634"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDV4033587.1"
                     /translation="MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLT
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTED
                     VAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLP
                     AFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
                     "
BASE COUNT          561 a          533 c          562 g          553 t
ORIGIN      
        1 tattgggtta aactatgaat aacattgcgc cgcaatcacc tgtaatgcgt cgcctgacgc
       61 agcaggataa tcccgccatc gcccgcgtca ttcgtcaggt atccgccgaa tacggtctta
      121 ccgctgataa aggctacacc gtcgccgatc cgaacctgga cgagttgtat caagtgtata
      181 gtcagccggg tcatgcatat tgggtggttg agtacgatgg tgaagtggtc ggcggcggtg
      241 ggattgcgcc attaaccggg agtgagtcgg acatttgcga actgcagaag atgtattttc
      301 ttccggctat tcgcggtaaa gggctggcga aaaaactggc cttaatggcg atggagcagg
      361 cacgagagat gggcttcaaa cgctgctatc tggaaacgac cgcttttttg aaagaagcga
      421 ttggtttgta tgaacattta ggttttcaac atatcgacta tgcacttggc tgcacgggcc
      481 atgtagattg tgaagtgcgg atgctacgcg aactctaaaa aaatgcccgc tagtgtgtgc
      541 tatcgggcat tttaatcaat taattagtgg cgaaccccgt catcgtcttc atcgacaaaa
      601 tcttcatcgt cgccgtcttc gccgttagga tcttcaaagt aagtgcccca accgtcgtac
      661 tcaacgtcaa atttctccgc cagcgtcatc agttgttcaa cctgggcatc gatcagatcg
      721 gcattcaacg cgcactcgct gaggatgtcg cagcaaatca cgatatcacc atcttcaact
      781 tccagctctt ctggatcggt cacttcgtaa ccgagtttaa acgcttcaac tgctgctttt
      841 tccagggttt ccagatcgtc tgcggaaaga tggtgttcga tggtgtacag cgcgtccgga
      901 tcgctgccat cttccagtaa ttcttcaata atcaaacgtg tttcttcacg ctgttcttcc
      961 agttgttccg ggtttgccat ggctcattcc tcttaatgtc ctgccgatac tcttattgtc
     1021 acacaccact gacattgcct ccacctttgt gacaaagatt tatgctttag acttgcaaat
     1081 gaataatcat ccatataaat tgaattttaa ttcattaagg cgttagccac aggagggatc
     1141 tatgtccggg ttttatcata agcatttcct gaaattactc gatttcacgc cagctgaact
     1201 caacagcctg ctgcagttag ccgcgaagct gaaagccgat aagaaaagcg gcaaagaaga
     1261 agccaaactc actggtaaaa acatcgcgct catcttcgaa aaagactcga cccgtacccg
     1321 atgctctttc gaagttgccg catatgacca gggtgctcgc gttacttatc tcggcccaag
     1381 cggcagtcaa attggtcata aagagtcgat taaagacact gcccgcgtgc tgggtcgcat
     1441 gtatgacggt attcagtatc gcggctatgg tcaggagatt gtcgaaacac tggcggaata
     1501 cgctggcgtg ccggtatgga acggcctgac caatgagttt caccccacgc agttgctggc
     1561 ggatctcctc accatgcagg agcatttacc cggtaaagca ttcaacgaaa tgacgctggt
     1621 ctatgcaggt gacgcacgta acaacatggg caattcgatg ctcgaagctg cggcgcttac
     1681 cggtctggat ttgcgtctgg tcgcgccaca ggcatgctgg ccggaagctg cgctggttac
     1741 ggaatgccgc gccctggcac agcaaaatgg cgggaatatt acgctgacgg aagatgtagc
     1801 caaaggagtt gaaggtgctg actttatcta taccgatgta tgggtgtcga tgggggaagc
     1861 aaaagagaaa tgggcagaac ggattgcatt actgcgtgat tatcaggtga acagcaagat
     1921 gatgcagttg accggtaacc cggaggtcaa attcctccac tgcctgcccg cgtttcatga
     1981 cgaccagacg acgcttggta agaaaatggc ggaagagttt ggcctacatg gcggaatgga
     2041 agtgactgat gaggtcttcg aatctgccgc cagcattgtt tttgatcagg cggaaaaccg
     2101 catgcatacc atcaaagcgg tgatggtcgc gacgctcagt aaataattga tatcgctata
     2161 aagatgccgg gaaatacaaa aacatcccgg catcacatta ttttatgca
//
LOCUS       DAPHKZ010000260         2100 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.265, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000260 DAPHKZ010000000
VERSION     DAPHKZ010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.265"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            17..1744
                     /locus_tag="RH288_004635"
     CDS             17..1744
                     /locus_tag="RH288_004635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDV4033588.1"
                     /translation="MRNKNIIMLLMSSLILSGCGPQPENKESQQQQPSTPTEQQVLAA
                     QQAAIKEAEQSAAAAKALAQQEVQQYSDKQALQGRLQEAPTFARAAKAKATHIANPGT
                     ARYQQFDDNPVKQVAQNPLATFSLDVDTGSYANVRRFLNQGLLPPPDAVRVEEIVNYF
                     PSDWDIKDKQSIPASKPIPFAMRYELAPAPWNEQRTLLKVDILAKDRKSEELPASNLV
                     FLIDTSGSMISDERLPLIQSSLKLLVKELREQDNIAIVTYAGDSRIALPSISGSHKAE
                     INAAIDSLDAEGSTNGGAGLELAYQQATKGFIKGGINRILLATDGDFNVGIDDPKSIE
                     SMVKKQRESGVTLSTFGVGNSNYNEAMMVRIADVGNGNYSYIDTLSEAQKVLNSEMRQ
                     MLITVAKDVKAQIEFNPAWVTEYRQIGYEKRQLRVEHFNNDNVDAGDIGAGKHITLLF
                     ELTLNGQKASIDKLRYAPDNKLAKSDKTKELAWLKIRWKYPQGKESQLVEFPLGPTIN
                     APSEDMRFRAAVAAYGQKLRGSEYLNNTSWQQIKQWAQQAKGEDPQGYRAEFIRLIEL
                     ADGVTDISQ"
     gene            complement(1815..>2100)
                     /locus_tag="RH288_004636"
     CDS             complement(1815..>2100)
                     /locus_tag="RH288_004636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416772.1"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="deubiquitinase"
                     /protein_id="HDV4033589.1"
                     /translation="SQSCGAFVCMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAE
                     EQYEIDFQHRLANRNCYLDKYGDANINHYYRNLEIKHSQPKNRASGKRVS"
BASE COUNT          607 a          441 c          507 g          545 t
ORIGIN      
        1 tttaaaagga ttttatatgc gaaataaaaa tataatcatg ttgcttatga gtagtttgat
       61 tttgtcagga tgtgggccgc aacctgagaa taaggaaagt cagcaacaac aacccagtac
      121 tcccacagag cagcaagtgc ttgccgcgca gcaagctgca ataaaagagg ctgagcaaag
      181 cgccgccgcc gcgaaagcct tggcccagca agaagtgcaa caatattcag acaaacaggc
      241 tttacagggg cgattgcagg aagcgccaac atttgcaaga gcggctaaag caaaagctac
      301 acatatcgca aatccaggaa ccgctcgcta ccagcagttc gatgataatc cggttaagca
      361 ggtagcgcaa aatccgttgg cgacgtttag tcttgacgtt gacactggca gttatgcgaa
      421 tgtaaggcgt ttcctcaatc aagggctgtt acctccgcca gacgctgtgc gggtggagga
      481 gatagtcaat tatttcccgt ctgattggga tatcaaagac aaacaatcta ttccggcctc
      541 taagccaata cctttcgcta tgcgctacga attggcacct gcaccatgga atgaacagcg
      601 aacattgctg aaagttgata tcctggcgaa agatcgcaaa agtgaagagt taccagcttc
      661 taatctggtc tttcttatcg acacttctgg ttcaatgatt tctgatgaac gtttgccact
      721 tatccagtct tcgttgaaat tattggtcaa agaacttcgt gagcaggata acattgccat
      781 cgtgacctac gctggcgact cccgtattgc attgccttct atctccggga gtcataaggc
      841 ggaaattaat gccgcaattg attcgctgga tgccgaaggc agtaccaatg gcggtgccgg
      901 gctggaactg gcttatcagc aggcgacgaa ggggtttatt aagggcggca tcaatcgcat
      961 tttattagcc actgacggtg actttaacgt tggcattgac gatccaaaat cgattgaatc
     1021 aatggtcaaa aaacagcggg agtctggtgt tactctgtcg acgtttggcg tggggaatag
     1081 caattacaac gaggcaatga tggtgcgaat tgccgatgtt ggtaacggca actacagcta
     1141 cattgatacc ctctctgaag cgcagaaagt attgaatagt gaaatgcggc agatgttgat
     1201 taccgtagca aaagatgtca aagcgcaaat tgagtttaac cccgcgtggg taacggaata
     1261 ccgtcagatt ggttatgaaa agcgccaact tcgggtggaa cattttaata acgacaacgt
     1321 tgatgcaggg gatataggcg caggcaaaca tataacgttg ttattcgaat taacgctgaa
     1381 cgggcaaaaa gcatcaattg ataagttacg ctatgccccg gataacaaat tagcgaaatc
     1441 ggacaaaacg aaagaactgg cctggttaaa aattcgctgg aaatacccgc agggaaaaga
     1501 aagtcagtta gttgaattcc cgctggggcc aacaataaac gcgccctctg aagatatgcg
     1561 ttttcgcgca gcagtagctg catatgggca aaagttacgc ggttctgaat acctgaacaa
     1621 tacctcctgg cagcagatca aacagtgggc tcagcaggca aaaggggaag atccacaggg
     1681 ttacagggcg gaatttattc gcctgattga actggcggat ggtgtgactg acatcagtca
     1741 gtgatgactg tttagcaaac tatgttcgac cagtcagcat atttgctgac tggtcgaatt
     1801 aattaacaat gatgttaact cactcttttg ccggatgctc tatttttggg ttgtgagtgt
     1861 tttatttcta agtttctata ataatgattg atatttgcat cgccatattt atctaaataa
     1921 caatttctgt ttgccagtcg atgttgaaaa tcaatttcgt actgctcttc tgctgaatat
     1981 tttttaaatc tgtcagcata gttttttaat aacgtatagg gggcgctgtc agaattgctt
     2041 tccctttgtt caatcacttc ctgggctgcc atgcacacaa atgcaccgca actttggctt
//
LOCUS       DAPHKZ010000261         2086 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.266, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000261 DAPHKZ010000000
VERSION     DAPHKZ010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2086
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.266"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(67..>2086)
                     /locus_tag="RH288_004637"
     CDS             complement(67..>2086)
                     /locus_tag="RH288_004637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV4033590.1"
                     /translation="NGEQRVSSGGSAIDTTINNGGTMSIAAGGSGTGIIQNNGGAIRA
                     NTSAILSGTNVNGSFSITNGSARNMLLENGGLLMVLQGHQAIDTQVSKGGELQVESGS
                     ELLGTTLIKDDGKLSGNQITNNGVLHFLDNSSANYSGTLDGTGSLNLDGGKLTLSGNF
                     SQDSGIFIQNHGTMIMDNLRAMANVTIEPDATLRLENGSLLAGRITGDGKKGGNLIVA
                     DSVWKLSGDSTINSLDMSNGTVDFHSIQSPQFKTKLEGVTLNIGQLSGNGTFLMNTDI
                     ASYTGDKLNITGNANGNFVLNIKNTGQEPVSPGNPLPVVYTGGGDAVFTVNGGKVDAG
                     VWEYYLSKDNTNWYLKSDTTQPGNPEPGIPNPPVRHTTKSTDAVLNMASAPTYIFNSE
                     LQGLRFRNSEKSENSRTSGGVWGHYIGSDKHISSKGAGYSLTQYGIVTGGDKRFDLSD
                     GVLSLGAFVSFSDNNIRHNRGGKSSIDSKSVGLYMTYDTHGYYIDGVLKFNRFKNELR
                     THMSDGTMVSGDYHQNGFGGSLEVGKYFSLNENTWLLPYARTTALAVNDDNISLSNGM
                     KAEINTTHSFQGEVGVNLGMDLDVGKTKIRPYLTAGVSHEFSNHNKVKINKAYDFTND
                     ISGTTGKYGLGMDVQLTSNASIWGEANYLKGNNVESPVTGTVGFKINF"
BASE COUNT          548 a          514 c          374 g          650 t
ORIGIN      
        1 cttttctaat aattagtaat tcagatgccc aaccgatatg gtcgggcatc tgatgcacat
       61 caggcgttaa aagtttatct tgaagccaac agtccctgtt accggtgact ctacattgtt
      121 accttttaaa taattagcct ctccccatat actggcattt gatgttagct gaacatccat
      181 acccaaaccg tactttccgg ttgtcccgga tatgtcgtta gtaaaatcat aggctttatt
      241 gattttaacc ttattatgat ttgaaaattc atgactgact cctgcggtca ggtagggcct
      301 tattttggtt ttaccaacat caaggtccat ccctaaatta acaccaacct caccctggaa
      361 agaatgtgtt gtgtttattt cagccttcat tccattagat agactgatat tgtcatcatt
      421 cacagcaaga gctgttgttc gggcataagg aagtaaccag gtattctcat tcagagaaaa
      481 atacttgccc acctccaggc taccaccgaa accattttga tgataatctc ccgaaaccat
      541 agttccatca ctcatatggg tacgcaactc atttttgaaa cggttgaatt tgagtacacc
      601 atctatatag tatccgtgag tatcatacgt catgtacaag ccaacacttt tactatcaat
      661 agaacttttc cctcctcgat tatgcctgat attgttatca gagaaggaaa caaatgcccc
      721 taatgacaac accccatcgc ttaggtcaaa acgcttatct ccgcccgtca ctattccgta
      781 ttgggtcagg gagtaacccg ctcctttgct gctgatgtgt ttatctgatc ctatatagtg
      841 cccccatact cccccagaag tacgtgagtt ttctgatttt tcactgttac ggaatcgcag
      901 cccttgtaat tcactgttaa agatatatgt cggagcgctt gccatattca gtacagcatc
      961 agtcgacttt gtggtgtgcc gtactggagg attgggtata cccggttccg gattacctgg
     1021 ttgcgtagta tcagatttta gataccagtt agtattatct ttactcagat aatattccca
     1081 aactcctgca tccacttttc ctccgtttac tgtaaataca gcatctcctc caccggtata
     1141 aaccactggt aatgggttac ccggggatac aggctcctga ccggtatttt tgatattcaa
     1201 aacaaaatta ccgtttgcat tccctgtgat gtttaattta tcaccagtat atgatgcaat
     1261 atcagtattc atcaagaagg tgccatttcc tgataactgt ccgatattta acgttactcc
     1321 ctcaagtttt gttttaaact gaggggactg tattgaatga aaatccacgg ttccattact
     1381 catgtctaat gagttaatag tagagtctcc ggataatttc cagacagagt cagccactat
     1441 cagatttcca cctttcttcc catccccagt aatgcgccca gccaggaggc taccattctc
     1501 taagcgcaga gttgcatcag gctcgattgt cacatttgcc atagcccgta gattatccat
     1561 tatcattgtt ccatgatttt ggataaaaat accgctatcc tgagaaaaat taccactgag
     1621 tgttaatttt cccccatcca gattcagact accggtacca tccagtgttc cgctatagtt
     1681 tgctgaacta ttgtcgagaa aatgcagaac cccattattg gttatctggt tgccagacag
     1741 tttgccatcg tctttaatca aggttgtacc caatagctca gaaccgctct caacctgtaa
     1801 ttcaccacct ttagagacct gggtatctat agcctgatgg ccttgcagaa ccatcaggag
     1861 tccaccattt tctaacaaca tatttctggc gctaccatta gtaatgctga agctaccatt
     1921 tacgttcgtt ccactcagga tggccgatgt gttcgctctg atagcgccac cattgttttg
     1981 aattattccc gttccactac cacctgcggc aatactcatt gtccctccat tgttaatggt
     2041 tgtgtcaata gcactgccac cactggagac tcgctgctca ccgtta
//
LOCUS       DAPHKZ010000262         1983 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.267, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000262 DAPHKZ010000000
VERSION     DAPHKZ010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1983
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.267"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            113..1759
                     /gene="mqo"
                     /locus_tag="RH288_004638"
     CDS             113..1759
                     /gene="mqo"
                     /locus_tag="RH288_004638"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDV4033591.1"
                     /translation="MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSA
                     TLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISI
                     EKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
                     QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIAS
                     LQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLL
                     QESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLD
                     GKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVML
                     SEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIA
                     ALLGASPGASTAAPIMLDLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
                     LQYTSEVLGLKYDKPQAADSTPKPQLKPKPVQKEVADIAL"
BASE COUNT          487 a          475 c          584 g          437 t
ORIGIN      
        1 aaattagaat ataatttata aacattattt aaatgttgtt acttaagtgt taccgttgat
       61 gccgcgcaaa tctcacctgc aataaagcga ctaaaagtaa ggcattaaca agatgaaaaa
      121 agtgactgcc atgctcttct cgatggccgt ggggcttaat gccgtttcga tggcggcaaa
      181 agcgaaagcg tctgaggagc aggaaactga tgtactgttg attggcggcg gcattatgag
      241 cgccacgttg gggacctatt tacgcgagct ggagcctgaa tggtcgatga ccatggtgga
      301 gcgcctggag ggtgtcgcgc aggagagttc gaacggctgg aataacgccg gaaccgggca
      361 ttctgcactg atggaactga actacacccc gcaaaacgcc gatggcagca tcagtattga
      421 aaaagcagtc gccattaacg aagcatttca gatttcccgc cagttctggg cgcaccaggt
      481 tgagcgcggc gtgctgcgta ctccgcgttc atttatcaat accgttccgc atatgagctt
      541 tgtctggggc gaggataacg ttaatttcct gcgcgcccgt tacgccgcgt tgcaacaaag
      601 ctcgctgttt cgcggtatgc gttactctga agatcacgcg cagatcaaag agtgggcacc
      661 gttagtgatg gaagggcgcg atccgcaaca gaaagtggca gccacgcgta cggaaattgg
      721 taccgatgtg aactacggcg agatcacccg ccagttaatt gcttccttgc agaagaaatc
      781 taacttctcg ctgcaactca gcagcgaagt ccgcgcccta aagcgtaatg acgataacac
      841 ctggaccgtt accgttgccg atctgaaaaa tggcactgca cagaacattc gtgccaaatt
      901 tgtctttatc ggcgcgggcg gtgcggcgct gaagctgtta caggaatcgg ggattccgga
      961 agcgaaagac tacgccggtt tcccggtggg cggacagttc cttgtttcgg aaaacccgga
     1021 cgtggttaat caccatctgg cgaaggttta cggtaaagca tccgttggcg caccaccgat
     1081 gtcggttccg catatcgata cccgcgttct ggacggtaaa cgcgtagtgc tgtttgggcc
     1141 atttgccacc ttctcaacca aattcctcaa aaacggttca ttgtgggatc tgatgagttc
     1201 caccaccacc tctaacgtga tgccgatgat gcacgtcggg ctggataatt tcgatctggt
     1261 gaaatatctg gtgagtcagg tgatgttgag tgaagaggat cgttttgaag cgttgaaaga
     1321 gtactatccg caggcgaaaa aagaggactg gcgtttgtgg caagcggggc agcgcgtgca
     1381 gattatcaag cgtgatgccg agaaaggtgg cgtactgcgt ctgggtactg aagtcgtcag
     1441 tgaccagcaa gggaccattg ccgcgctcct gggggcatcg ccaggggcgt caaccgccgc
     1501 gccgattatg ttggatctgc tggaaaaagt atttggcgat cgcgtttcca gcccgcaatg
     1561 gcaggctacg ttgaaagcga tcgttccgtc ttatggacgc aagctgaacg gtgatgtagc
     1621 ggcaacagaa cgcgagttgc agtacaccag cgaagtgctg gggctgaaat acgacaagcc
     1681 gcaggcagca gatagtacgc cgaaaccgca gttgaaaccg aaacccgttc aaaaagaagt
     1741 ggcggatatt gcgttgtaat gatgtgccac atccggcatg gtatgccggg gatgtggcgt
     1801 atgctgataa gacgcgccag cgtcttatca ggcaaccggc tcgggcgtta gatgtcggat
     1861 gcggcgtaac cgccttatcc aatctacggg gtggagcact tcacagcggt gtaggcctga
     1921 taagacgcgc cagcgtcgca tcaggcaacc ggcttgggcg ttagatgtcg gatgcggcgt
     1981 aac
//
LOCUS       DAPHKZ010000263         1971 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.268, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000263 DAPHKZ010000000
VERSION     DAPHKZ010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1971
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.268"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..401
                     /locus_tag="RH288_004639"
     CDS             <1..401
                     /locus_tag="RH288_004639"
                     /inference="COORDINATES: protein motif:HMM:NF024700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDV4033592.1"
                     /translation="EDGSKFELPFAFESAGTQSAFIRLHNIMQCLKKGTACFIDELGD
                     DLHPHMVKPILELFISKETNPLHAQLIFTCHKPELINYLGKYRVLITEKKFNRSECYR
                     LDDFPSSEARVDDNIAAKYLAGAFGGVPDL"
     gene            398..931
                     /locus_tag="RH288_004640"
     CDS             398..931
                     /locus_tag="RH288_004640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033593.1"
                     /translation="MMKPRRVKRGVERTKLLMCEGITDKRFADCLKRLLTTRTAGFSV
                     RLDDAGGGGPKSAIMAAINHAGSFDKRVVFIDSDLAIPTDALSAARNRDIQIIQSSPF
                     CLEGFLMRLMGHNQQFVNSQEAKESFHRLYNLKNVVTQEWYEEYITLQHINSVLSDHR
                     HVCREVLSDLCDVFTVF"
     gene            complement(1541..>1971)
                     /locus_tag="RH288_004641"
     CDS             complement(1541..>1971)
                     /locus_tag="RH288_004641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033594.1"
                     /translation="ARAILEKYIPFIITGNKNKNVDSIILSLLIVTSANMVNLETGKH
                     EEPLEPYLLRSASIGGLNLNPNNYIVRMVAFNSFWFFLLIPKRPVTSKVKKEFWDEFK
                     RKNHLHGVLLKRNNTSIKITKDKTTYLHPDLIEKMWRKIK"
BASE COUNT          554 a          323 c          404 g          690 t
ORIGIN      
        1 aagaagatgg ttccaagttt gagttaccct ttgcattcga atctgctgga acacaaagtg
       61 catttatcag attgcataat attatgcaat gtctgaaaaa aggaacagca tgctttattg
      121 atgaacttgg tgatgatttg cacccacata tggttaaacc tatattagag ttgtttatca
      181 gtaaagaaac aaacccgtta catgcacagt taatttttac ttgtcataaa cccgaattga
      241 taaattattt gggtaagtac cgtgtgttga ttactgagaa aaaattcaat agaagtgaat
      301 gttatcgact tgatgatttt ccatccagtg aggcgcgagt cgacgataat attgcggcta
      361 aatatttagc tggtgctttt ggaggagtac cagacttatg atgaagccca gacgtgtaaa
      421 gcgtggagtt gaacgaacta agcttttgat gtgcgaagga attactgaca aaagatttgc
      481 tgattgttta aaacgactct taacaactag gactgcaggg tttagtgtta ggttagatga
      541 tgccggcggt ggaggaccga aatcagctat aatggctgct ataaaccatg ctggtagttt
      601 tgataaaaga gttgttttta ttgactcaga ccttgcaata cctactgatg ctctatctgc
      661 tgctagaaat agagacatac aaatcattca atcctcacca ttttgtttgg aggggttttt
      721 aatgaggtta atggggcata atcaacaatt tgttaattcg caggaggcaa aagagtcatt
      781 tcacaggctc tataatttga aaaatgttgt aacacaagaa tggtatgaag agtatataac
      841 acttcagcat ataaactctg tgctcagcga tcataggcat gtttgtcgag aagttttatc
      901 ggacctgtgt gatgtattca ccgtatttta aaactgccct tgaggcaata tcgttaactt
      961 aaacaaagta gtactgtgtt tcagcggata acgggttttt gatattttaa cagtcttctg
     1021 ctttgatggt ctgggctttc atattactag ggagctgcgg ctcctttgcg tatcctcatt
     1081 tgtttcatca tcggttgact ggcgtctttt ttattgttgt aacttgatgt ttttttgttt
     1141 ttatttttgt tttttggctc tatctgatta tgattgatgg aggggggggg cgcagacacg
     1201 tgtatgcgag aacgtgctgt ggcaggttgg ttaacttccg atagtgcgag tattgaaagg
     1261 tctcttgccg ttatcgattt tacgtattta ttgtatgaga ggattttcac tacctcccac
     1321 cgaccatcta tgactgtgtg ctcctatctc tagggctgct atgtgccaga tgcggacata
     1381 ctcagcaata tagtgaataa attagtaggg gctaggttac agtaatgaac acattgaaca
     1441 ttaataccat taattttctt ctctggtgag tttgttccac tgcgtcattt aacctagtcc
     1501 ccattaatta tttttggtat tgtcaactgg aaaatttgtt ctactttatt tttcgccaca
     1561 tcttttctat taagtcagga tgcaaatatg tcgttttatc ttttgtgatc tttattgacg
     1621 tgttgtttct ttttaacaaa actccatgca gatgattttt tcttttaaat tcatcccaaa
     1681 attctttttt cactttggat gtaactggcc tctttggaat taacaaaaaa aaccaaaagc
     1741 tattaaatgc aaccatccta acaatataat tgttagggtt gaggtttaaa ccaccaatcg
     1801 atgcgcttct taatagatat ggttctaaag gctcttcatg tttaccagtt tccagattaa
     1861 ccatatttgc agaagttaca attagaaggg aaagaattat actatctaca tttttgtttt
     1921 tattgccagt gattatgaat ggtatgtatt tttctaaaat ggctctggca t
//
LOCUS       DAPHKZ010000264         1951 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.269, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000264 DAPHKZ010000000
VERSION     DAPHKZ010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1951
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.269"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1767
                     /locus_tag="RH288_004642"
     CDS             <1..1767
                     /locus_tag="RH288_004642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV4033595.1"
                     /translation="AGALQAANEAATKGFDDQTRRLKENMGTLETWADRTARAFKSMW
                     DAVLDIGRPDTAQEMLIKAEAAFKKADDIWNLRKDDYFVNDEARARYWDDREKARLAL
                     EAARKKAEQQTQQDKNAQQQSDTEASRLKYTEEAQKAYERLQTPLEKYTARQEELNKA
                     LKDGKILQADYNTLMAAAKKDYEATLKKPKQSGVKVSAGDRQEDSAHAALLTLQAELR
                     TLEKHAGANEKISQQRRDLWKAESQFAVLEEAAQRRQLSAQEKSLLAHKDETLEYKRQ
                     LAALGDKVTYQERLNALAQQADKFAQQQRAKRAAIDAKSRGLTDRQAEREATEQRLKE
                     QYGDNPLALNNVMSEQKKTWAAEDQLRGSWMAGLKSGWSEWEESATDSMSQVKSAATQ
                     TFDGIAQNMAAMLTGSEQNWRSFTRSVLSMMTEILLKQAMVGIVGSIGSAIGGAVGGG
                     ASASGGTAIQAAAAKFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYR
                     LMRGYATGGYVGGTGSPAQMRRSEGIRFEQNNNVVIQNDGTNGLPGPQMMKAVYDMAR
                     KGARDEIQTQMRDGGLFSGGGR"
     gene            1764..>1951
                     /locus_tag="RH288_004643"
     CDS             1764..>1951
                     /locus_tag="RH288_004643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4033596.1"
                     /translation="MKTFRWKVKPGMDVASVPSVRKVRFGDGYSQRAPAGLNANLKTY
                     SVTLSVPREEATVLESFL"
BASE COUNT          495 a          469 c          652 g          335 t
ORIGIN      
        1 gccggggcat tgcaggcggc gaacgaggcc gcaacgaaag ggtttgatga ccagacccgc
       61 cgcctgaaag agaacatggg cacgctggag acctgggcag acaggacagc gcgggccttc
      121 aaatccatgt gggatgcggt gctggatatt ggtcgtcctg ataccgcgca ggagatgctg
      181 attaaggcag aggctgcgtt taagaaagca gacgacatct ggaatctgcg caaggatgat
      241 tattttgtta acgatgaagc gcgggcgcgt tactgggatg atcgtgaaaa ggcccgtctt
      301 gcgcttgaag ccgcccgaaa gaaggctgag cagcagactc aacaggacaa aaatgcgcag
      361 cagcagagcg ataccgaagc gtcacggctg aaatataccg aagaggcgca gaaggcttac
      421 gaacggctgc agacgccgct ggagaaatat accgcccgtc aggaagaact gaacaaggca
      481 ctgaaagacg ggaaaatcct gcaggcagat tacaacacgc tgatggcggc ggcgaaaaag
      541 gattatgaag cgacgctgaa aaagccgaaa cagtccggcg tgaaggtgtc tgcgggcgat
      601 cgtcaggaag acagtgctca tgctgccctg ctgacgcttc aggcagaact ccggacgctg
      661 gagaagcatg ccggagcgaa tgagaaaatc agccagcagc gccgggattt gtggaaggca
      721 gaaagtcagt tcgcggtact ggaggaggcg gcacaacgtc gccagctgtc cgcacaggag
      781 aaatccctgc tggcgcataa agatgagacg ctggagtaca aacgccagct ggctgcactt
      841 ggcgacaagg ttacgtatca ggagcgcctg aacgcgctgg cgcagcaggc ggataaattc
      901 gcacagcagc aacgggcaaa acgggccgcc attgatgcga aaagccgggg gctgactgac
      961 cggcaggcag aacgggaagc cacggaacag cgcctgaagg aacagtatgg cgataatccg
     1021 ctggcgctga ataacgtcat gtcagagcag aaaaagacct gggcggctga agaccagctt
     1081 cgcgggagct ggatggcagg cctgaagtcc ggctggagtg agtgggaaga gagcgccacg
     1141 gacagtatgt cgcaggtaaa aagtgcagcc acgcagacct ttgatggtat tgcacagaat
     1201 atggcggcga tgctgaccgg cagtgagcag aactggcgca gcttcacccg ttccgtgctg
     1261 tccatgatga cagaaattct gcttaagcag gcaatggtgg ggattgtcgg gagtatcggc
     1321 agcgccattg gcggggctgt tggtggcggc gcatccgcgt caggcggtac agccattcag
     1381 gccgctgcgg cgaaattcca ttttgcaacc ggaggattta cgggaaccgg cggcaaatat
     1441 gagccagcgg ggattgttca ccgtggtgaa tttgtcttca cgaaggaggc aaccagccgg
     1501 attggcgtgg gaaatctcta ccggctgatg cgcggctatg ccaccggcgg ttatgtcggt
     1561 ggcaccggaa gtccggcgca aatgcggcgt tcagagggta tcaggtttga gcagaacaac
     1621 aacgtggtga ttcagaacga cggtacgaat ggtctgccag gtccacagat gatgaaagca
     1681 gtgtatgaca tggcccgcaa gggtgcccgt gatgaaattc agacacagat gcgtgatggt
     1741 ggcctgttct ccggaggtgg acgatgaaga ccttccgctg gaaagtgaaa cccggtatgg
     1801 atgtggcttc ggtcccttct gtaagaaagg tgcgctttgg tgatggctat tcccagcgag
     1861 cgcctgccgg gctgaatgcc aacctgaaaa cgtacagcgt gacgctttct gtcccccgtg
     1921 aggaggccac ggtactggag tcgtttctgg a
//
LOCUS       DAPHKZ010000265         1916 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.270, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000265 DAPHKZ010000000
VERSION     DAPHKZ010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1916
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.270"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..527
                     /locus_tag="RH288_004644"
     CDS             <1..527
                     /locus_tag="RH288_004644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HDV4033597.1"
                     /translation="GQKSAGDTSFTLAWMPGEQGQQALLAWFNEGDTRAYKIRFPNGT
                     VDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTAATGMTVTPASTSVV
                     KGQSTTLTVAFQPEGATDKSFRAVSADKTKATVSVSGMTITVKGVAAGKVNIPVVSGN
                     GELAVVAEITVTDS"
     gene            543..965
                     /locus_tag="RH288_004645"
     CDS             543..965
                     /locus_tag="RH288_004645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HDV4033598.1"
                     /translation="MFLKTESFEYNGVSVTLSELSALQRIEHLALLKRQAEQAGSSLN
                     RQVSVEDLVKTGAFLVAMSLWHSHPQKTKMPSMNEAVKQIEQEVLTTWPTEAIAQAEN
                     VVMRLSGMSEFVVNDAPEQADDAGPAEPVSAGKCSTVS"
     gene            947..1381
                     /locus_tag="RH288_004646"
     CDS             947..1381
                     /locus_tag="RH288_004646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HDV4033599.1"
                     /translation="MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHY
                     FHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLNRREADEEPEDDVLMQKAAGLAG
                     GVRFGPDGNEVIPASPDVADMTEDDVMLMTVSEGIAGGVRYG"
     gene            1374..>1916
                     /locus_tag="RH288_004647"
     CDS             1374..>1916
                     /locus_tag="RH288_004647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail length tape measure family protein"
                     /protein_id="HDV4033600.1"
                     /translation="MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTESDAKKTAAVV
                     EQSMNRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQS
                     GLTADRMLVLSRAGQAAGLTF"
BASE COUNT          425 a          484 c          611 g          396 t
ORIGIN      
        1 aggggcagaa atctgccgga gataccagct tcacgctggc gtggatgccc ggagagcagg
       61 ggcagcaggc gctgctggcg tggtttaatg aaggggatac ccgtgcctat aaaatccgct
      121 tcccgaacgg cacggtcgat gtgttccgcg gctgggtcag cagtatcggt aaggcggtga
      181 cggcgaagga agtgatcact cgcacggtga aagtcaccaa cgtgggacgt ccgtcgatgg
      241 cagaagatcg cagcacggta acagcggcaa ccggcatgac cgtgacgcct gccagcactt
      301 cggtggtgaa agggcagagc accacgctga ccgtggcatt ccagccggaa ggcgcaaccg
      361 acaagagctt ccgtgcggtg tctgcggata aaacaaaagc caccgtgtcg gtcagtggta
      421 tgaccatcac cgtgaaaggt gttgctgcag gcaaggtcaa cattccggtt gtatccggta
      481 atggtgaact tgctgtggtt gcagaaatca ccgtcaccga cagttaatcc ggagagtcag
      541 cgatgttcct gaaaaccgaa tcatttgaat ataacggtgt gagcgtcacg ctttctgaac
      601 tgtcagccct gcagcgaatt gagcatctcg ccctgctgaa acgacaggca gaacaggcgg
      661 gatccagtct caatcgacag gtgagcgtgg aagatctcgt caaaaccggt gcttttctgg
      721 tggcgatgtc cctgtggcat agccatccgc agaagacaaa gatgccgtcc atgaatgaag
      781 ccgttaaaca aattgagcag gaagtgctta ccacctggcc cacagaggca attgctcagg
      841 ctgaaaatgt ggtaatgcgt ctgtccggta tgtctgagtt tgttgtgaat gatgcacctg
      901 aacaggcaga tgacgccggg ccagcagagc ctgtttctgc gggaaagtgt tcgacggtga
      961 gctgagtttt gccctgaaac tggcgcgtga gatggggcga cccgactggc gcgccatgct
     1021 tgccgggatg tcatccacgg agtatgccga ctggcaccgc ttttacagta cccattattt
     1081 tcatgatgtt ctgctggata tgcacttttc cgggctgacg tacaccgtac tcagcctgtt
     1141 tttcagcgat ccggatatgc atccgctgga tttcagtctg ctgaaccggc gcgaggctga
     1201 cgaagagcct gaagatgatg tgctgatgca gaaagcggca gggcttgccg gaggcgtccg
     1261 ctttggcccg gacgggaatg aagttatccc cgcttccccg gatgtggcgg acatgacgga
     1321 ggatgacgta atgctgatga cagtatcaga agggatcgca ggaggagtca ggtatggctg
     1381 aaccggtagg cgatctggtc gttgatttga gtctggatgc ggccagattt gacgagcaga
     1441 tggccagagt caggcgtcat ttttccggta cggaaagtga tgcgaaaaaa acagcggcag
     1501 tcgttgaaca gtcaatgaac cggcaggcgc tggctgcaca gaaagcgggg atttccgtcg
     1561 gacagtataa agccgccatg cgtatgctgc ctgcacagtt caccgacgtg gccacgcagc
     1621 ttgcaggcgg gcaaagtccg tggctgatcc tgctgcaaca gggtggtcag gttaaggact
     1681 ccttcggcgg gatgatcccc atgttcaggg ggcttgccgg tgcgatcacc ctgccgatgg
     1741 tcggggccac ctcgctggcg gtggcgaccg gtgcgctggc gtatgcctgg tatcagggca
     1801 actcaaccct gtccgatttc aacaaaacgc tggtcctttc cggcaatcag tcgggtctga
     1861 cggcagatcg catgctggtc ctgtccagag ccgggcaggc ggcagggctg acgttt
//
LOCUS       DAPHKZ010000266         1908 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.271, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000266 DAPHKZ010000000
VERSION     DAPHKZ010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1908
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.271"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            61..168
                     /locus_tag="RH288_004648"
     CDS             61..168
                     /locus_tag="RH288_004648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033601.1"
                     /translation="MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV"
     gene            374..1657
                     /gene="gltA"
                     /locus_tag="RH288_004649"
     CDS             374..1657
                     /gene="gltA"
                     /locus_tag="RH288_004649"
                     /EC_number="2.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HDV4033602.1"
                     /translation="MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYD
                     EFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWSEMHSDGMKIARPRQLYTGYEKRDFKSDIKR"
BASE COUNT          519 a          458 c          427 g          504 t
ORIGIN      
        1 tcatctaatt tgacaatcat tcaacaaagt tgttacaaac attaccagga aaagcatata
       61 atgcgtaaaa gttatgaagt cggtatttca cctaagatta acttatgtaa cagtgtggaa
      121 gtattgacca attcattcgg gacagttatt agtggtagac aagtttaata attcggattg
      181 ctaagtactt gattcgccat ttattcgtca tcaatggatc ctttacctgc aagcgcccag
      241 agctctgtac ccaggttttc ccctctttca cagagcggcg agccaaataa caaacgggta
      301 aagccaggtt gatgtgcgaa ggcaaattta agttccggca gtcttacgca ataaggcgct
      361 aaggagacct taaatggctg atacaaaagc aaaactcacc ctcaacgggg acacagctgt
      421 tgaactggat gtgctgaaag gcacgctggg tcaagatgtt attgatatcc gtactctcgg
      481 ttcaaaaggt gtgttcacct ttgaccctgg cttcacttca accgcatcct gcgaatctaa
      541 aattactttt attgatggtg atgaaggtat tttgctgcac cgcggtttcc cgatcgatca
      601 gctggcgacc gattctaact acctggaagt ttgttacatc ctgctgaatg gtgaaaaacc
      661 gactcaggaa cagtatgacg aatttaaaac tacggtgacc cgtcatacca tgatccacga
      721 gcagattacc cgtctgttcc acgctttccg tcgcgactca catccaatgg cagtcatgtg
      781 tggtattacc ggcgcgctgg cggcgttcta tcacgactcg ctggatgtta acaatcctcg
      841 tcatcgtgaa attgccgcgt tccgcctgct gtcgaaaatg ccgaccatgg cagcgatgtg
      901 ttacaagtat tccattggtc agccatttgt ttacccgcgc aacgatctct cctacgccgg
      961 taacttcctg aatatgatgt tctctacgcc gtgcgaaccg tatgaagtta atccgattct
     1021 ggaacgtgct atggaccgta ttttgatcct gcacgctgac catgaacaga acgcctccac
     1081 ctccaccgtg cgtaccgctg gctcttcggg tgcgaacccg tttgcctgta tcgcagcagg
     1141 tattgcttca ctgtggggac ctgcgcacgg tggtgctaac gaagcagcgc tgaaaatgct
     1201 ggaagaaatc agctccgtta aacacattcc ggaatttgtt cgtcgtgcga aagataaaaa
     1261 tgattctttc cgcctgatgg gcttcggtca ccgcgtgtac aaaaattacg acccgcgcgc
     1321 caccgtaatg cgtgaaacct gccatgaagt gctgaaagag ctgggcacga aggatgacct
     1381 gctggaagtg gctatggagc tggaaaacat cgcgctgaac gacccgtact ttatcgagaa
     1441 gaaactgtac ccgaacgtcg atttctactc tggtatcatc ctgaaagcga tgggtattcc
     1501 gtcttccatg ttcaccgtca ttttcgcaat ggcacgtacc gttggctgga tcgcccactg
     1561 gagcgagatg cacagtgacg gtatgaagat tgcccgtccg cgtcagctgt atacaggata
     1621 tgaaaaacgc gactttaaaa gcgatatcaa gcgttaatga ttgattgcta agccgtttac
     1681 tttccggacc cgcctttaat agagcgggtt cttttttata tggctgaaca taaaaaattg
     1741 taaaaattaa accagatgca aatacccatt aataaggtga aaaaatgaga caagtcacat
     1801 actgagcaga atgataagtt tatttttata cttccctgcc ggtaacattg ttaacccaat
     1861 gaaaattatg catatccatc ccaccccatc cttcatctca ttaaacaa
//
LOCUS       DAPHKZ010000267         1902 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.272, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000267 DAPHKZ010000000
VERSION     DAPHKZ010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1902
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.272"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            260..1291
                     /locus_tag="RH288_004650"
                     /pseudo
     CDS             260..1291
                     /locus_tag="RH288_004650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1606..>1902
                     /locus_tag="RH288_004651"
     CDS             1606..>1902
                     /locus_tag="RH288_004651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV4033603.1"
                     /translation="MTHSTIKQLTIKAILEYIEDNIEVKSIDIESIVCFSGYSRRYLQ
                     SLFKSHMGVPIGRYIQLRRVSRAAVLLRLTSLSLASIAGKLCYDSQQTFTREFKK"
BASE COUNT          556 a          418 c          442 g          486 t
ORIGIN      
        1 atacccaaac gacagctagt accccatcaa tctgcatata aaattgctgg ccacgctaca
       61 tcctgttagc gaaagtactg attagtactt caatggccag tgcaaaactg aaaatccaat
      121 tcaggcaaat aagggatgat gataccgtaa gtaaatcgtg atatcgcgtt aaatatattg
      181 ccacatccac acacgttgag tttgcttatt gtgcactgat ttctatgatg taccctgatc
      241 ttagtcagag gtgactcaca tgacaaaaac agtatcaacc agtaaaaaaa ccgtaaacag
      301 cattcgcctg aatttcgcag tgaagcacta aagcttgcgg aacgcatcgg tgttgctgcc
      361 gcaggccgtg gactcagctt gtatgaatca cagctctaca actggcgcag taaacagaaa
      421 aatcagcaga cttcctctga acgtgagctg ccggaacagg atgaagagct ggccatactc
      481 caaaaggtag cgacatactt cgcgaaacgc cagaaatgaa gtatgtcttt attgaaaaac
      541 atcaggctga gttcagcata caggcaatgt gccgcgtgcc cgcagcggcg ggtatatgtg
      601 gtatcggcgg cgggcaagga taaaagcaca cgtcagcagt tccgtcagta ctgcaacagc
      661 gttgtccacg ctgtttttac cctgtcaaaa ccgcgttacg gtgcactaag cctgcgccgt
      721 tagggactga gggcaaaagc ttcccggaag ttcagcctgg tcagtcaccg cgcacacagc
      781 ctgcctgtgt cagaaaatct gcttgagcag gatttttacg ctgttggccc gaaccagaag
      841 tggtcgggag acatcacgta cttacgtacg tgatgaaggc tggcagtatc tggcagtggt
      901 cattgacctg gggtcacgtg ccgctattgg ctggtcaatg tcaccacgca tgacagcgca
      961 aatagcctgc gatgccctgc agatggagct gtagcggcgt aagagaccac agaacgatat
     1021 cattcggagg ccagtactgc tctgcagatt atcaggcatt gctgaagcgg cataatctgc
     1081 gtggcagtat gatcgcaaaa gactgctgtt tcgatcatgc ctgcgaggaa atcttctttc
     1141 attcactgaa agtggaatgt atccacggag aactctttat tagctgggaa acaatatggg
     1201 caacagtgtt tagtgtttac aatcgctggc gacggcacag tggatgtggc gccttagtcc
     1261 tgaacaattt gaaaaccaga acctcgctta gggcggtcca tattacgtgg gtaagatcac
     1321 ccctcctgac catgagtggg aggaaggaaa cagaactcat ttaacgcact tgcaccacct
     1381 tcatatcaaa aaatacactt ttccaacgaa acttagtgtt aagtttatgt tgccttttgt
     1441 ctgtcacctc ttttaattta attgttatga atacctgatt tctgaagcca tacaaaaaac
     1501 gcgattttgt tggcttattg tgcattgtgt gctgcttgcg cacaataagc taatgcgaac
     1561 gtatagtaac cacattagac tttatgcgtc taaatgaggt taatgatgac gcacagcaca
     1621 attaagcaat tgacaataaa agcaattctc gaatacatcg aagacaatat tgaggttaaa
     1681 agtatcgata ttgaatcgat agtctgtttt tctggttaca gtaggagata tttgcaatct
     1741 ctgtttaagt ctcacatggg agtacccata gggaggtata tacaactcag aagagtttca
     1801 agggctgcgg tattattacg attgacatca ttatcattgg ccagtattgc aggcaaactc
     1861 tgttatgatt ctcaacaaac atttacaaga gagtttaaaa aa
//
LOCUS       DAPHKZ010000268         1884 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.273, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000268 DAPHKZ010000000
VERSION     DAPHKZ010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1884
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.273"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            135..1652
                     /gene="lysS"
                     /locus_tag="RH288_004652"
     CDS             135..1652
                     /gene="lysS"
                     /locus_tag="RH288_004652"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDV4033604.1"
                     /translation="MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDH
                     TSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     SLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG
                     DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK"
     gene            complement(1771..>1884)
                     /gene="ghoT"
                     /locus_tag="RH288_004653"
     CDS             complement(1771..>1884)
                     /gene="ghoT"
                     /locus_tag="RH288_004653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system toxin GhoT"
                     /protein_id="HDV4033605.1"
                     /translation="IIWFISHEKTHIRLLSAFLVGITWPMSLPVALLFSLF"
BASE COUNT          521 a          412 c          458 g          493 t
ORIGIN      
        1 agtgatatca acttgaggta agcgttagtt tcgataagat aaactgagtt actaatagtc
       61 gaggcagata atacagtgta ccgatctgtc tctttatcta cgctaaattg aaagctggat
      121 ttagaggaac caaaatgtct gaacaagaaa cacggggagc caatgaggct attgatttta
      181 acgatgaact gagaaatcgc cgcgaaaaac tggcggcact acgtcagcaa ggtgtggcgt
      241 ttcccaatga ttttcgccgc gaccatacct ctgaccagtt gcacgaagag tttgatgcga
      301 aggataacca ggaactggaa tccttaaaca ttgaagtctc ggttgctggc cgaatgatga
      361 cccgtcgtat catggggaaa gcctcctttg taacgttgca ggatgtcggt ggccgtattc
      421 aactgtacgt tgcaagagat agcctgccag aaggtgttta taacgatcag tttaaaaaat
      481 gggatctggg tgacattatc ggtgcccgcg gtacgctgtt taagacgcaa acgggtgagc
      541 tttccattca ctgtactgag ctgcgcctgc tgactaaagc actacgtcct ttaccagata
      601 aattccatgg tctgcaggat caggaagtcc gttatcgtca acgttatctg gacctcatcg
      661 ctaacgataa atcccgtcaa acgtttgttg tccgttcaaa aattctggcc gctatccgtc
      721 aattcatggt cgcgcgcggc tttatggaag tagaaacccc gatgatgcag gtaattccag
      781 gtggggcatc tgctcgcccg tttattaccc atcataatgc tctggattta gatatgtatc
      841 tgcgtatcgc gccggagctg tatctgaaac gtctggttgt aggcggtttt gaacgggtat
      901 tcgaaatcaa ccgtaacttc cgtaatgaag gtatttctgt tcgccataat cctgagttca
      961 caatgatgga actctacatg gcgtatgcgg attaccacga tttgattgaa ctgacagagt
     1021 cactgttccg caccctggca caagaggttc tgggtaccac taaagtcact tatggcgagc
     1081 atgtgtttga tttcggcaaa ccgtttgaaa aactcaccat gcgcgaagca atcaaaaaat
     1141 atcgtccaga aaccgatatg gccgacctgg ataattttga tgctgctaaa gcattagctg
     1201 aatctatcgg tattacggta gagaaaagct gggggttggg acgtattgtc acagagatct
     1261 ttgatgaagt ggcagaagca catctgattc agccaacctt tattacggaa tatccggcag
     1321 aagtgtcccc gctggcacgc cgtaatgatg ttaacccgga aatcaccgac cgttttgaat
     1381 tcttcatcgg tggtcgtgaa atcggtaatg gttttagcga attaaacgac gcagaagatc
     1441 aggctgaacg tttccaggaa caggttaatg ctaaagctgc aggtgacgac gaagccatgt
     1501 tctatgacga agattacgtg actgcgctgg aatatggtct gccgccaacc gctggtctgg
     1561 gtattggtat cgaccgaatg attatgctgt ttactaacag ccatactatt cgcgacgtta
     1621 ttctcttccc ggcgatgcgc ccacagaaat aaatttcact ttaatgaacg aagcagtcag
     1681 gcgactgctt cgttcatcgt tccgcaaatc cagttttgag gagagacgct tcgtttcacg
     1741 ataaccagcg ggtccactca actacagctc ctaaaagaga gaaaaaagta atgccacagg
     1801 cagactcatt ggccaggtta ttccgaccag gaatgcacta agtaaacgaa tatgtgtttt
     1861 ctcatgtgag ataaaccaga taat
//
LOCUS       DAPHKZ010000269         1864 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.274, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000269 DAPHKZ010000000
VERSION     DAPHKZ010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1864
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.274"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1180
                     /locus_tag="RH288_004654"
     CDS             <1..1180
                     /locus_tag="RH288_004654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YhiJ/YhiL family protein"
                     /protein_id="HDV4033606.1"
                     /translation="SDIIYKVDGLSIIARNFFTLLSGNFKPDWRWDVSKETFTKEKFD
                     SYVKSVFSKIDFYKQCGVINPQNANTAYFGDTDGRVGAVLYALLVSGHIGIREKGWSL
                     LCELLKHEEMASSAYKHKNNKVLYDLLNTRDMILNELHQHVFLKDDAITPCIFLGDHT
                     GDRFSTIFGDKYILTLLNSMRNMEGNKDSRINKNVVVLAGNHEINFNGNYTARLANHK
                     LSAGDTYNLIKTLDVCNYDSERQVLTSHHGIIRDEEKKCYCLGALQVPFNQMKNPTDP
                     EELANIFNKKHKEHMDDPLFHLIRSNTLKPTPVYANYFDNTTDFRPARERIFICGETL
                     KGEDPSKYIRQKYGHHGPGVDHNQQFDNGIMGLNSLKEARDKNNKIIYSSGLSCFQPH
                     "
     gene            1442..>1864
                     /locus_tag="RH288_004655"
     CDS             1442..>1864
                     /locus_tag="RH288_004655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033607.1"
                     /translation="MKIGTVAGTNDSTTTIATNDMVQEHVTNFTKELFGYIANGIGDD
                     ISSIARTMLGEVVEKIDDWQIERFQQSIQDDKISFTIQTDHSEKYSMLSGMRAHILRR
                     NNNYQFIVTINSKNYGCSLDNTDVNWCSIVYLLNNMTVN"
BASE COUNT          634 a          292 c          358 g          580 t
ORIGIN      
        1 atcagatata atttataaag ttgatgggct ttctatcata gcgagaaatt tctttactct
       61 tcttagtggt aatttcaaac ctgactggcg ttgggatgtc tctaaagaga cgtttactaa
      121 ggaaaagttt gatagctatg ttaaatctgt gttttcaaaa atagacttct ataaacagtg
      181 tggtgtgatt aacccacaaa atgccaacac ggcttatttt ggcgatacag atggaagagt
      241 aggcgctgta ctttatgcat tgctcgtttc agggcatata ggcatcaggg aaaagggttg
      301 gagtttatta tgtgaattat taaaacacga agagatggct tcatctgcat acaaacataa
      361 aaataataaa gtgctctacg atttattaaa tacgagagac atgatcttga atgagttgca
      421 tcaacatgtt tttttaaagg acgatgcgat aaccccttgt atcttccttg gggatcatac
      481 aggcgataga tttagtacta tttttggtga taaatatatc cttactttgc taaattctat
      541 gcgaaatatg gagggtaata aagatagccg tattaataaa aatgtcgtcg ttctggctgg
      601 aaatcatgaa atcaatttta atggtaacta tactgcacga ctagcaaatc ataaactctc
      661 tgccggtgat acgtataact taattaaaac gctcgatgtt tgtaattatg actcagaaag
      721 gcaagtttta accagtcatc acggaataat aagagatgaa gaaaaaaaat gttattgtct
      781 cggtgctttg caggttccat ttaatcagat gaaaaatcct actgatcctg aggaattagc
      841 caatattttt aataaaaaac ataaagaaca catggatgat cctctattcc atctaatccg
      901 aagcaatact ttgaaaccca cacctgtata tgctaattat tttgataaca ctactgattt
      961 cagaccagca cgtgaacgta tcttcatatg tggggagaca ctcaaaggtg aagaccccag
     1021 caaatacatt agacaaaaat atgggcatca tgggcccggg gtagatcata atcaacaatt
     1081 tgataatggt attatggggc taaattccct gaaggaagca cgtgataaaa ataataaaat
     1141 aatttattcc tcagggctta gttgttttca accacattaa aactccatga atacggtggt
     1201 atgtcttttt aatcctgcca gtatttcata ggttttctta atcgattgta gaggcatgtt
     1261 ctgatgacgc ctctacaatc tttagggact ttctctgcta tgagataaga aatttcatat
     1321 tatgctttga ggctgaatga tttgtgcaaa atataattat tttcccatcg aacatgaggt
     1381 gtatgtcata agataaaatg ttaactatgt attcctcgcg gtaaataata tgaggtaaaa
     1441 tatgaaaatt ggaactgtgg caggcactaa cgacagtaca acgacaatcg caacaaatga
     1501 tatggtgcaa gagcatgtta ccaacttcac taaagaactg tttgggtata ttgcaaatgg
     1561 tataggtgat gatatatcaa gtattgccag gacaatgctc ggtgaggttg tggaaaaaat
     1621 agatgattgg caaatagaac ggttccaaca atctattcaa gatgacaaaa tttcatttac
     1681 catacaaacg gatcattcag aaaaatatag tatgctatcg ggcatgcgtg ctcatattct
     1741 acgtaggaat aataattatc agtttattgt gacaattaat agcaaaaatt acggttgctc
     1801 tcttgataat accgatgtta attggtgcag tattgtttat ttacttaata atatgacagt
     1861 aaat
//
LOCUS       DAPHKZ010000270         1848 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.275, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000270 DAPHKZ010000000
VERSION     DAPHKZ010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1848
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.275"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..1848
                     /locus_tag="RH288_004656"
                     /pseudo
     CDS             1..1848
                     /locus_tag="RH288_004656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439272.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family protein"
BASE COUNT          650 a          357 c          351 g          490 t
ORIGIN      
        1 taccgagagt tgaataaagc agcacagcgt agcattacag cgccagacag gataggagaa
       61 agaaaaacat aggtttatca acgagataca atgattgaaa gaggtgataa cagcggtgtt
      121 tatcagtatg gtcgtgctga acatttcacc cacattatat ctgacaaacc ttccccaaaa
      181 gataaatatg ttgcatatgc tattaacatt cctgactatg agctggcagc cgatgtatat
      241 aatattaacg tgacgtcacc ttccggacag caagaaacat ttaaaatatt aatcaatcta
      301 gaacatctac ggcaaacact tgagcgtaaa tctcttactg ctgttcagaa atcacaatgt
      361 gaaatcatca cccccaaaaa acctggcgaa gcgattcttc atgcttttaa tgccacctac
      421 cagcagatca gagaaaatat gtctgaattt gcacgttgcc attatgggta tatacaaatc
      481 cctccagtga caactttccg cgccgacgga ccagaaactc ccgaagaaga aaagggttac
      541 tggtttcatg cttatcaacc cgaagatctt tgtaccatcc ataatccaat gggagatttg
      601 caggatttta ttgcattggt taaagatgct aaaaaatttg gtatcgatat cattcctgat
      661 tataccttta actttatggg aattgggggt agtggtaaaa atgacctgga ttatccctct
      721 gctgatatac gagcgaagat cagtaaagat atagaaggtg gtatccctgg ctattagcaa
      781 ggtcaggttt tgattccatt cattaaagat ccagtaacaa aagaacgtaa acaaatccat
      841 ccagaagata tacatctcac tgcaaaagac ttcgaagcaa gtaaagataa catctctaag
      901 gatgaatggg aaaacctcca tgcattaaaa gaaaagcgtt taaatggaat gcctaaaaca
      961 acacccaaaa gtgaccaggt tattatgttg caaaatcaat acgttcgtga aatgcgaaaa
     1021 tatggcgtac gaggtttacg ttatgatgcg gcaaaacact caaaacatga acaaatagaa
     1081 agatcaataa ccccaccgct taaaaattat aatgagcggt tacacaatac taacttattt
     1141 aacccaaaat atcataaaaa agccgttatg aattacatgg aatatctggt aacttgtcag
     1201 ttggatgaac aacaaatgtc atcactgctt tatgaaagag atgatttaag cgccattgat
     1261 ttttcattgc tcatgaaaac gataaaagcc ttttcatttg gtggagatct tcaaaccctt
     1321 gcatcaaaac cgggttccac aatctcaagt atcccatcag aaagacggat attgattaac
     1381 attaaccacg attttcctaa caatggtaat cttttcaatg actttctatt taaccatcaa
     1441 caagatgaac aattagcaat ggcatatata gccgctctgc cgttcagcag gcctttagtt
     1501 tactgggatg gccaagtatt aaaatcaacg actgaaatta aaaattatga tgggtccacg
     1561 cgtgtcggcg gtgaggcgta gcttaataaa ggttgctcta cctatcagca gctctacaat
     1621 gaattccacg cattatatat agataaagca ggaatatgga gcgcatttga gggtgtatct
     1681 gcaactaaaa acgttctggc ctttagtcgt ggggattctg tgaacattaa tcactctcct
     1741 catgatggac tagttataat aaataaagga aacgaagaag ttgaaggtac ctggcctaac
     1801 aaattgcaac ctggaatata caaaaacatg gggagtaata gcgttaac
//
LOCUS       DAPHKZ010000271         1805 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.276, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000271 DAPHKZ010000000
VERSION     DAPHKZ010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.276"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            112..327
                     /gene="essD"
                     /locus_tag="RH288_004657"
     CDS             112..327
                     /gene="essD"
                     /locus_tag="RH288_004657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416074.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HDV4033608.1"
                     /translation="MKSMDKLTTGVAYGTSAGNAGFWALQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDRRKAARGE"
     gene            332..643
                     /locus_tag="RH288_004658"
     CDS             332..643
                     /locus_tag="RH288_004658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdfR family protein"
                     /protein_id="HDV4033609.1"
                     /translation="MTQDYELVVKGVRNFENKVTVTVALQDKERFDGEIFDLDVAMDR
                     VEGAALEFYEAAARRSVRQVFLEVAEKLSEKVESYLQHQYSFKIENPANKHERPHHKY
                     L"
     gene            640..1173
                     /locus_tag="RH288_004659"
     CDS             640..1173
                     /locus_tag="RH288_004659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HDV4033610.1"
                     /translation="MNTKIRYGLSAAVLALIGAGASAPQILDQFLDEKEGNHTMAYRD
                     GSGIWTICRGATVVDGKTVFPNMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQK
                     AGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
                     VIRRDQESALTCWGIEQ"
     gene            1170..1667
                     /locus_tag="RH288_004660"
     CDS             1170..1667
                     /locus_tag="RH288_004660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2514 domain-containing protein"
                     /protein_id="HDV4033611.1"
                     /translation="MNQIFMVIFLVLSGFIVGNVWSDRGWQKKWAERDAAALSQEVNA
                     QFAARIIEQGRTIARDEAVKDAQQKSAEISARAAYLSDSVNQLRAEAKKYAIRLDAAK
                     HTADLAAAVRGKTTKTAEGMLTNMLGDIAAEAQLYAEIADERYIAGVTCQQIYESLRD
                     KKHQM"
BASE COUNT          529 a          363 c          460 g          453 t
ORIGIN      
        1 atgtgtatgt ttttttagcg ccgttgagaa caacgtgtgc tgtcaaaact accccgtaga
       61 ctccgatctt ttcaaacata ttgcaccatc cgtgtacatc ggggtgagga tatgaaatca
      121 atggataagt taacaacagg tgttgcctat ggcacatcgg cgggtaatgc tggtttctgg
      181 gcattgcagt tactcgataa agtaactccg tcacagtggg ctgcaatcgg tgtgctgggt
      241 agcctggttt ttggcctgct gacgtatctg acaaatcttt atttcaagat taaagaagac
      301 aggcgtaagg ctgcgagagg agagtaatcc aatgactcaa gactatgaac tggttgtgaa
      361 aggagtccgt aattttgaga ataaagttac ggtaactgta gccttacagg acaaagaacg
      421 ctttgacggt gaaatttttg acctggatgt cgccatggac cgtgttgaag gagctgcgct
      481 ggagttttat gaggcagcag ccagaaggag cgtccggcaa gtcttcctgg aagtagcaga
      541 aaaattgtca gaaaaagttg agtcttatct gcagcatcag tactccttta agattgaaaa
      601 tcctgccaat aagcacgagc gtcctcatca taaatatcta tgaacacaaa aatcagatac
      661 ggcctgtcgg ctgccgttct ggcgctgatt ggtgctggcg catctgctcc tcagatactt
      721 gaccagtttc tggacgaaaa agaaggtaac cacacaatgg cataccgcga tggttctggc
      781 atatggacca tctgtcgggg tgccacagtg gtggatggaa aaaccgtttt tcccaatatg
      841 aaactgtcga aggaaaaatg cgaccaggtc aacgccattg agcgtgataa ggcgctggca
      901 tgggtggagc gcaatattaa agtaccactg accgaaccac aaaaagcggg tatcgcgtca
      961 ttttgtccct ataacattgg ccccggtaag tgtttcccgt cgacgtttta taagcggctg
     1021 aatgctggtg atcgtaaagg tgcatgcgaa gcgattcgct ggtggattaa ggatggcgga
     1081 cgcgattgcc gcattcgttc aaataactgt tacggtcagg ttattcgtcg tgaccaggag
     1141 agcgcattaa cctgctgggg gatagaacag tgaatcagat attcatggtg atttttctcg
     1201 tgttgtcagg atttatcgtc ggaaatgtct ggagcgaccg aggatggcaa aaaaaatggg
     1261 cggaacgtga tgctgccgca ttatcacaag aggtaaatgc tcaatttgct gctcgaataa
     1321 ttgaacaggg gcgaactata gcccgtgatg aggctgttaa agatgcgcaa cagaaatctg
     1381 ctgaaatttc tgccagggct gcttatctgt ctgatagtgt taaccagttg cgtgccgaag
     1441 caaaaaaata tgccatacgc cttgacgcag cgaagcatac cgcagatctt gccgctgccg
     1501 tcagaggcaa aacaaccaaa accgccgaag gaatgctcac caacatgctc ggagatattg
     1561 cagcagaagc tcagctttat gctgaaattg ctgacgaacg ctacatcgca ggagtgactt
     1621 gtcaacagat ctatgaatct ttaagagata aaaagcatca aatgtagggt aatattaaat
     1681 cggaacattt acatcgcgga atgtaaaatt taaataaaaa ggactcttcc atgagccaaa
     1741 attcctgaaa tcttaagggt aagataaaag gtcttaatca gaatgacacg ttttattaat
     1801 aaata
//
LOCUS       DAPHKZ010000272         1796 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.277, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000272 DAPHKZ010000000
VERSION     DAPHKZ010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1796
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.277"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            164..667
                     /locus_tag="RH288_004661"
     CDS             164..667
                     /locus_tag="RH288_004661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HDV4033612.1"
                     /translation="MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLR
                     AQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLA
                     QLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
                     VVSHQLH"
     gene            complement(746..997)
                     /locus_tag="RH288_004662"
     CDS             complement(746..997)
                     /locus_tag="RH288_004662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2766 domain-containing protein"
                     /protein_id="HDV4033613.1"
                     /translation="MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQ
                     LKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH"
     gene            complement(1112..1198)
                     /gene="azuC"
                     /locus_tag="RH288_004663"
     CDS             complement(1112..1198)
                     /gene="azuC"
                     /locus_tag="RH288_004663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein AzuC"
                     /protein_id="HDV4033614.1"
                     /translation="MKLRKILKSMFNNYCKTFKDVPPGNMFR"
     gene            1461..1784
                     /locus_tag="RH288_004664"
     CDS             1461..1784
                     /locus_tag="RH288_004664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecR-like lipofamily protein"
                     /protein_id="HDV4033615.1"
                     /translation="MRLLILTLSLITLAGCTVTRQAHVSEVDAATGIVRLVYDQAFLQ
                     HAHTDRYVSRGIADRACQQEGYTHAVPFGQPVGNCSLFAGSLCLNTEFTLSYQCHHSA
                     FPVFL"
BASE COUNT          467 a          428 c          391 g          510 t
ORIGIN      
        1 ttttcttata cccgttcaga cgttattctt atttcagatc atcgtcagaa ttgactccac
       61 gatcacattt cggaccggca gaaaggaatt attctgcaaa cagtaattat ggtgttttga
      121 tttatcttgc acctctccac ttctggatat aaggatatta ggtatggcaa ccgctggaat
      181 gcttctcaaa ctcaactctc aaatgaaccg cgagttttac gcatccaatc tctaccttca
      241 cctgagtaac tggtgttctg aacagagtct gaacggcacc gccactttcc ttcgcgccca
      301 ggcacagagt aatgtgaccc aaatgatgcg catgtttaac tttatgaaga gtgtcggcgc
      361 tacccccatc gttaaagcca ttgatgttcc cggtgaaaaa ctgaactctc tggaagaact
      421 gttccaaaaa acgatggaag aatacgagca acgttctagt acgttggcac agttagccga
      481 tgaagcgaaa gaactgaatg atgattcaac cgtcaatttc ctgcgcgatc tggaaaaaga
      541 acagcagcat gatggtctgt tgctgcaaac cattcttgat gaagtgcgca gtgcgaaact
      601 tgcgggtatg tgccctgtgc agaccgacca acatgttctg aatgtcgtgt cacaccagct
      661 gcattgatca tcatcggcgc taatgcattg cgccgatgaa ggttttgaga aaccgctgcc
      721 tcatctgttt gaagcagcgg tttttttaat gggattcacc ctgtggggta aacttgagtt
      781 caataagcgc gatggctttt tggattgccc gcatggtgac cgggtctgcg gcggcgggat
      841 ggttagtaaa gtcgatattc ttcagctgac tggacatttt ttcacgaact tcaacgggcg
      901 cgattacatc gagaacatcc agaatttgtt tgataaccaa ctggcaagca accacatcag
      961 aaaccaattc ctgatcggca ttcagcggct gggacatcgt aaactcctga tagcattttg
     1021 aaagccgtta tagtagcgac ttcacatctt cagcgatagt cacatccacc gtcatcagga
     1081 cacaaaaaaa cctgccggag caggtttttt gttatcggaa catattgcct ggcggtacgt
     1141 ctttgaacgt cttgcaatag ttattgaaca tacttttcag gattttgcgc agtttcatcg
     1201 cggcactccg accatttgtt atacaggtgt tattgtcttt gcgcttataa tatgacaacc
     1261 atcacaaaaa tcaatcttta tgtgatacaa atcacataaa taccccttta atgttataaa
     1321 aatgataatc aaaaaacagc ccccctattt ctgacaccta cagatggcaa gaaatagcgc
     1381 ctgccaggcg tcttttccgg ccattgtcgc agcactgtaa cgcgtaaaat agtgctttct
     1441 cttactcttc tggctggacc atgagacttc tgattctgac tctttcatta ataacgctgg
     1501 cggggtgtac ggttactcgc caagcccatg tgagcgaagt tgacgcggca acaggtattg
     1561 tacggttagt ttatgaccag gcttttttgc agcatgccca taccgatcgt tatgtcagtc
     1621 gcgggatcgc cgatcgcgca tgccagcagg aaggctatac ccacgcggtc ccctttggtc
     1681 agccagtagg caactgtagc ctttttgcgg gttccttatg tttgaatacg gaattcactt
     1741 tgtcatatca gtgccatcat tccgccttcc ctgtctttct ctaaatattt taatca
//
LOCUS       DAPHKZ010000273         1762 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.278, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000273 DAPHKZ010000000
VERSION     DAPHKZ010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1762
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.278"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            57..356
                     /locus_tag="RH288_004665"
     CDS             57..356
                     /locus_tag="RH288_004665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV4033616.1"
                     /translation="MTELAQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGEL
                     TRITGLSASATSQHLARMRDEGLIDSQRDAQRILYSIKNEAVNAIIATLKNVYCP"
     gene            366..890
                     /gene="ygaP"
                     /locus_tag="RH288_004666"
     CDS             366..890
                     /gene="ygaP"
                     /locus_tag="RH288_004666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YgaP"
                     /protein_id="HDV4033617.1"
                     /translation="MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLS
                     VLEQSGLPAKLRHEQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKKAGLP
                     VAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSGFFLLSGFVGAGLLFAGISGFCG
                     MARLLDKMPWNQRA"
     gene            complement(937..1341)
                     /gene="stpA"
                     /locus_tag="RH288_004667"
     CDS             complement(937..1341)
                     /gene="stpA"
                     /locus_tag="RH288_004667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HDV4033618.1"
                     /translation="MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEE
                     EQQQRELAERQEKISTWLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFTDV
                     NGETKTWTGQGRTPKPIAQALAEGKSLDDFLI"
BASE COUNT          482 a          400 c          386 g          494 t
ORIGIN      
        1 tatatgttgc atttttagtt tagagtttac ttaatttaga aaatacttaa ataaatatga
       61 ctgaactcgc gcaattacag gccagtgccg aacaggcagc ggccttattg aaagcaatga
      121 gccaccctaa acgattgctg attctgtgca tgcttagcgg ttcccccggc accagcgcgg
      181 gagagctgac gcgcattacc ggactgagtg cctctgcgac atcacagcat ctcgctcgta
      241 tgcgggacga agggcttatc gacagccaac gggatgccca acgcattcta tattccatta
      301 aaaatgaggc ggtaaatgcc attatcgcca ccctgaaaaa tgtctattgt ccgtaaggag
      361 tcactatggc tttgacaacc atttcgccgc atgatgcaca agaattaatc gcacgcggcg
      421 caaagttaat cgatattcgt gatgctgatg aatatcttcg tgaacatatt cctgaagcag
      481 atctggctcc attatccgtg ctggaacagt caggtcttcc ggctaaatta cgtcacgagc
      541 aaattatatt ccactgccag gcaggtaaac gcaccagtaa taatgccgat aaattagcag
      601 cgattgccgc ccccgcagaa atctttttac tcgaagatgg gattgatggc tggaaaaaag
      661 caggattgcc agtagcggta aataaatctc aacccttgcc gttaatgcgc caggtgcaga
      721 tcgctgcggg tggtttaata ttaatcggcg ttgtactggg ttataccgta aatagcggtt
      781 tcttcttatt aagtggcttt gttggtgccg ggttactgtt tgcaggaatc agcggttttt
      841 gtggaatggc aaggttgtta gataagatgc cgtggaacca acgagcttga gaagcgacgc
      901 cggacgcgcc ctagcagcga catccggcct cagtaattag atcaggaaat cgtcgagaga
      961 tttaccttct gccagcgcct gagcaattgg cttcggtgta cggccctgac cggtccaggt
     1021 tttagtttca ccgttaacat cggtgaattt atatttcgcc ggacgcggct ggcgtttttt
     1081 accagcgcgt ggtgcagcag cagagctatt acccaataac tcttccgggt taattccgtc
     1141 agctttcatc agctccagcc aggtgctaat tttttcctgg cgctctgcca gttcacgctg
     1201 ctgctgttct tcttcttcac gtctttcttt agtgacaacc ctgaattttt cgagcatttc
     1261 ttcaagaacg tcaatggaga attcgcgagc catcgcacgg agggtgcgaa tgttatttaa
     1321 actttgtaac attacggaca taataaagaa aaccttttaa cgccaaaaca aaaaaagtat
     1381 ttcgtcgcgt agtgtaagcg atcacttatt atatttccac aaaatttaat ctatttacag
     1441 tcctgcgcga gattatttca gctgttattt tctgaaactc tcagaataat ttcaagatta
     1501 tatattagcc attttgatga gtaatttaga ttattggtga acagagcggc gctctctgct
     1561 cgctaattcc gcaagcctga caaaatcaaa gtgaataaaa atgcaatata acagaataaa
     1621 agaaaacatc catcactggt gctttctgct gttaatgtac attgtctggc ataaaaaatg
     1681 ctgaaaatga cccagctact acatacaccg aattctctac gcttatagcg ttacctcacc
     1741 cccaaacttt cattagtgat at
//
LOCUS       DAPHKZ010000274         1743 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.279, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000274 DAPHKZ010000000
VERSION     DAPHKZ010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.279"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..113)
                     /locus_tag="RH288_004668"
     CDS             complement(<1..113)
                     /locus_tag="RH288_004668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033619.1"
                     /translation="MSEENKENGFNHVKTFTKIIFIFSVLVFNDNEYKITDA"
     gene            252..923
                     /gene="queE"
                     /locus_tag="RH288_004669"
     CDS             252..923
                     /gene="queE"
                     /locus_tag="RH288_004669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HDV4033620.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     EKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLL
                     PLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKH
                     PVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHK
                     YLNIA"
     repeat_region   1263..1656
                     /inference="COORDINATES: alignment:crt:1.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1263..1290
                     /rpt_unit_seq="gtgttccccgcgccagcggggataaacc"
BASE COUNT          469 a          377 c          408 g          489 t
ORIGIN      
        1 gcatcggtaa ttttatattc gttatcatta aaaactaata cagaaaaaat aaatataatt
       61 ttggtgaatg ttttgacatg attaaatcca ttttctttat tttcttctga cataatacgt
      121 tactcccttt aattattaac gatatgtttc gcatttttct ttaaacctgc ctgtaacaga
      181 atgttaataa gacatgattg ttgtggcagg atctgcaata attaacaatt atccacttca
      241 cagagaatgc tatgcagtac ccgattaacg agatgttcca gaccctgcaa ggtgagggtt
      301 actttaccgg cgttcccgcc atttttattc gtttacaggg atgcccggtt ggctgtgcct
      361 ggtgcgacac caaacacacc tgggaaaagc ttgaggatcg ggaagtctcc cttttcagca
      421 ttctggcgaa gaccaaagag agtgataagt ggggggctgc gagcagtgaa gatttgctgg
      481 ctgtcattgg tcgccaggga tacaccgcgc ggcatgtggt gattacgggt ggtgagcctt
      541 gcattcatga tttgctgcca ctgactgatc tgctcgaaaa gaacggtttt agctgccaga
      601 tcgaaaccag tggtactcat gaggtacgct gcacaccgaa tacctgggtt accgtatcgc
      661 caaagctgaa catgcgcggc ggctatgaag tgttgtcaca ggcactggag cgagccaacg
      721 aaatcaagca tccagtgggg cgcgtacgcg atattgaagc actggatgaa ctactggcaa
      781 cgctgaccga tgataaaccg cgagtcattg cactgcagcc gattagccaa aaggatgatg
      841 ccacacgttt gtgcattgaa acctgcattg cgcgtaattg gcgtttgtcg atgcaaacac
      901 ataaatatct aaatattgcc tgattaaaca tttataagcg ttataaatgg gtggaacctg
      961 taaagacttc tactcattta tattgtttgt cgcctctgaa aactcctcca ttttacccat
     1021 ccagggctaa tcattagcat tctctacaaa ttctgtggca ttaatttttc gctggagtga
     1081 aaattattgc ggtaaagttt ggtagatttt agtttgtata gagttatttt aaatatttac
     1141 ctttttaatc aatggattaa gtgctcttta acataatgga tgtgttgttt gtgtgatact
     1201 ataaagttgg tagattgtga ctggcttaaa aaatcattaa ttaataatag gttatgttta
     1261 gagtgttccc cgcgccagcg gggataaacc ggcaaaaacc gggcaatcgc aaaaaggcgt
     1321 aatgtgttcc ccgcgccagc ggggataaac ctgtgtttgc ggcattaacg ctcaccagca
     1381 tttcgtgttc cccgcgccag cggggataaa ccgacgtggt catgggtgct gctgttgcag
     1441 agccagtgtt ccccgcgcca gcggggataa accgagcaga tacacggctt tgtattccgt
     1501 gcgcccgtgt tccccgcgcc agcggggata aaccgaatag caatagtcca tagatttgcg
     1561 aaaacaggtg ttccccgcgc cagcggggat aaaccggagc ctgacgagac tactgaggcc
     1621 gttctgtcga gttccccgcg ccagcgggga taaaccacca tataacccgt tatctctttc
     1681 tcaagttttt atattagcag tacttgtaat aagcaacata tccacgtaac acctcatgtt
     1741 caa
//
LOCUS       DAPHKZ010000275         1743 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.280, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000275 DAPHKZ010000000
VERSION     DAPHKZ010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.280"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..561
                     /locus_tag="RH288_004670"
     CDS             <1..561
                     /locus_tag="RH288_004670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDV4033621.1"
                     /translation="LNNMALNDKSACVRATAIESTAQRCKKNPIYSPKIVEQSQITAF
                     DKSTNVRRATAFAISVINDKATIPLLINLLKDPNGDVRNWAAFAININKYDNSDIRDC
                     FVEMLQDKNEEVRIEAIIGLSYRKDKRVLSVLCDELKKNTVYDDIIEAAGELGDKTLL
                     PVLDTMLYKFDDNEIITSAIDKLKRS"
     gene            589..1547
                     /locus_tag="RH288_004671"
                     /pseudo
     CDS             589..1547
                     /locus_tag="RH288_004671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312497.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            1559..>1743
                     /locus_tag="RH288_004672"
     CDS             1559..>1743
                     /locus_tag="RH288_004672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDV4033622.1"
                     /translation="MKACLLLFFYFSFICQLHGADVKIKQNESMMGSTAMTYDLSEEK
                     LMKLKYKSQHGDSEASFR"
BASE COUNT          544 a          324 c          412 g          463 t
ORIGIN      
        1 ttgaacaata tggcattgaa tgataagagc gcttgcgttc gagctacggc aatcgagtca
       61 acggctcagc gatgcaagaa aaacccaatt tattcaccta aaatagtaga acaatctcaa
      121 attactgctt ttgataaatc gactaatgtc agacgtgcta cagcatttgc tatttctgtt
      181 atcaatgata aagcaacaat tccactattg attaatctgt taaaagatcc aaatggagat
      241 gtcagaaact gggccgcatt tgcaataaat atcaataaat atgataatag tgatattagg
      301 gattgttttg tggagatgct tcaggataaa aatgaggaag tccgtattga agcaataatc
      361 ggactttcct acagaaaaga taaaagggtt ttatctgttt tatgcgatga gttaaaaaaa
      421 aatactgttt atgatgatat cattgaagct gcgggtgaat taggtgataa aacgctactt
      481 cctgttttag atactatgtt gtacaagttt gatgacaatg aaattataac ttccgctatt
      541 gataagctga agcgttcata gcgtgagttg cctatgcaca gtgggggatt cccgccggca
      601 cggtgcagat gctcgaccgg ctggaaagtg aaatcctggc tgaccgggtg agtgaggaaa
      661 gccgccgctg gctggcatcg tgcggcctga ccgtggagca gatgaaaaac cagatggacc
      721 cggtgtacac gccggcgcga aaaatccacc tgtaccactg cgaccatcgc ggcctgccgc
      781 tggcgctcat cagcacggaa ggggcaacag cgtggtgcgc agaatatgat gaatggggca
      841 acctgctgag tgatgagaac ccgcatcatc tgcagcagct cattcgcctg ccgggtcagc
      901 agtatgatga ggagtccggc ctgtattaca accgccaccg ctattatgac ccgctgctgg
      961 ggcggtatat cactcaggat ccgattggac tgaagggggg atggaatttt tatcagtatc
     1021 cgttgaatcc ggtcataaat gtagatccgc aaggtttggt tgatataaat ttataccccg
     1081 aaagtgatct tatccattct gtagctgatg agattaatat cccaggcgtt ttcacaatcg
     1141 gggggcatgg tacccccaca tctattgaat ccgcaacgcg cagtatcatg acagctaaag
     1201 atctagcata tctaattaaa tttgatggga attataaaga tgggatgaca gtttggttat
     1261 tttcttgtaa tacaggtaaa ggacaaaatt catttgctag ccaattagct aaagagttac
     1321 atacaaatgt aataggacct gacacgctat ggacgtggtg ggggcgagga actaatggta
     1381 agttaaaaat ggatacagtg ctaacagcac caacgaacct taattcaaat aaggatctaa
     1441 tggctataac aacaaaagac cttggtaatt ggataacata taggccatct gggcacccca
     1501 tttctaatat gcaaggtacg ccagaaaaac ccagtgatat aagataggtt gtagatgtat
     1561 gaaagcatgc ttgttactat ttttttattt ctcttttatt tgtcaattgc atggtgctga
     1621 tgtgaaaata aaacaaaacg aaagtatgat ggggtctaca gcaatgacct atgatttaag
     1681 tgaagaaaag ttgatgaaac tgaagtataa atcacaacat ggtgattcag aggcatcatt
     1741 tcg
//
LOCUS       DAPHKZ010000276         1688 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.281, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000276 DAPHKZ010000000
VERSION     DAPHKZ010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1688
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.281"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..588
                     /locus_tag="RH288_004673"
     CDS             1..588
                     /locus_tag="RH288_004673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HDV4033623.1"
                     /translation="MRTTNLLSLFVEWVKLFTDKVTRGGKMKKWMLAICLMFINEICH
                     ATDCFDLAGRDYKIDPDLLRAISWKESRYRVNAIGINPVTGYGSGLMQVDSQHFNELA
                     RYGIKPEHLTTDPCMNIYTGAYYLAIAFKKWGVSWEAVGAYNAGFRKTERQNQRRLAY
                     ASDVYRIYTGIKSSKGIRIPATKKSLPEINSVQNN"
     gene            complement(884..>1688)
                     /locus_tag="RH288_004674"
     CDS             complement(884..>1688)
                     /locus_tag="RH288_004674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV4033624.1"
                     /translation="FGRYNSIRRERPLTDDELMQFVPSVFSGDKHESRSERYTYIPTI
                     NIINKLRDEGFQPFFACQSRVRDLGRREYSKHMLRLRREGHINGQEVPEIILLNSHDG
                     SSSYQMIPGIFRFVCTNGLVCGNNFGEIRVPHKGDIVEQVIEGAYEVLGIFDKVTDNM
                     EAMKEIHLNSDEQHLFGRAALMVRYEDENKTPVTPEQIITPRRWEDKQNDLWTTWQRV
                     QENMIKGGLSGRSASGKNTRTRAITGIDGDIRINKALWVIAEQFRKWKS"
BASE COUNT          492 a          399 c          352 g          445 t
ORIGIN      
        1 gtgagaacca ccaacctgtt gagccttttt gtggagtggg ttaaattatt tacggataaa
       61 gtcaccagag gtggaaaaat gaaaaaatgg atgttagcca tctgcctgat gtttataaat
      121 gagatctgcc atgccactga ttgctttgat cttgcaggcc gggattacaa aatagatcct
      181 gatttactga gagcaatatc atggaaagaa tcccgttacc gggttaatgc catcggtatt
      241 aatccggtaa cgggatatgg cagcggactg atgcaggtag attcccagca ttttaacgaa
      301 ctggcccgct atggaattaa gccggaacat ctgacaacag atccctgcat gaacatttat
      361 accggtgctt attatctggc aatagccttt aaaaaatggg gcgtctcctg ggaggccgtt
      421 ggtgcataca atgccggatt caggaagacc gaacgccaga accagagacg tcttgcctac
      481 gcatcagatg tttaccggat ttataccggg ataaaaagca gtaaaggtat ccggattccg
      541 gccacgaaga aatcacttcc ggaaattaac agcgtgcaga acaattaatc ttacagacat
      601 tgtcagatac cggttatgcc gcaaaagcgg catggaaggc cacacacaaa aatatcatat
      661 gagtgacaat actgactggc cgaagccccg cgaagcggga acccatctta tatatacccg
      721 gtaactgcgc agcctcctgc cagaccattt ttcgcgggca caatatttac agacaaccgg
      781 aaagccagtt gatgaaattg aggtatatca gacgacacag cgatgccgaa gaatgataat
      841 ataagtaaag ccccgaaaat ttttcggggc tttacttata ttatcatgac ttccactttc
      901 tgaactgttc ggcaatcacc cataacgcct tgttgattct tatatcacca tcaatacctg
      961 taatggctct tgtcctagta tttttcccgg aggcacttcg ccccgataat ccacctttta
     1021 tcatattctc ctgaacccgc tgccaggttg tccagagatc gttctgttta tcctcccaac
     1081 gacggggagt aattatctgt tcaggcgtca ctggcgtttt attttcatct tcatacctga
     1141 ccatcagtgc agctctgcca aataaatgtt gctcgtcact gttaagatga atttctttca
     1201 tcgcctccat attatcagtg accttatcaa agataccgag tacttcatac gctccctcga
     1261 taacctgctc gacaatatca cctttatgtg gaacgcggat ttcgccaaaa ttatttccgc
     1321 acaccaggcc atttgtgcag acaaaacgaa aaattccggg gatcatctga taactggatg
     1381 aaccatcatg tgaattaagc aggataattt caggaacttc ctgcccgtta atatgccctt
     1441 ccctgcgaag acgtaacata tgtttactgt attcgcgacg tcccaaatca cgaacccgac
     1501 tctgacaggc aaagaatggc tggaaacctt catcacgtaa cttattgatg atattgattg
     1561 ttggaatata cgtataacgt tcactccggg actcatgttt atcaccggaa aataccgaag
     1621 gcacgaactg cattaattca tcatccgtta aaggacgttc acggcggatg gaattatacc
     1681 gaccaaaa
//
LOCUS       DAPHKZ010000277         1581 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.282, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000277 DAPHKZ010000000
VERSION     DAPHKZ010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1581
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.282"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..1581
                     /gene="espL1"
                     /locus_tag="RH288_004675"
                     /pseudo
     CDS             1..1581
                     /gene="espL1"
                     /locus_tag="RH288_004675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="type III secretion system effector EspL1"
BASE COUNT          496 a          328 c          299 g          458 t
ORIGIN      
        1 tattactgga aaccacgcct attaaagcta accatttgcg aagcatactg gattatattg
       61 aacaggaaca gttaactgct gaagatcgta accattgtat gaaactgtct aaaaaaatcc
      121 atagagaaaa aaactataca cccaacagta aatctcaatg gtagtgcatg ttttttgcaa
      181 tctccttctg acgctatttt ttgtcgccat ctgtcattgc aatacgccct tgattcattg
      241 agaaatggaa aaggcaaagt caacctgatt aaacattact cctccgttga atccatacag
      301 cagcatgtcc ccttagtccg ggacgcggag ttcagagcat tacttcgcca tcctcctgca
      361 gggagtcgcg ttatcgcgag taaggatttt ggcttcgctt tagatatttt cttttgtcga
      421 atgatggcaa acaatgtcag tcatatgtcc gcgattttat atatagacaa tcatactttg
      481 tcagtaaggc tacgaataaa gcagtcagtg tatggacaat taaattatgt tgtgtccgtt
      541 tacgacccga acgataccaa cgttgccgtc agagacaccc acaggacagc acggggcttt
      601 ctttcgcttg ataagttcat cagttcaggt cccgatgctc agacctgggc tgatagatat
      661 gttcgcaact gtgcaattgc tattctgccc ctattacctg tgggagttcc aggggctatt
      721 ttcgcgggta ttgcatcacg aatgccattt gcccctatac atccatcggc aatgttgtta
      781 ataatggcta caggccagac tcaacagctt attacattat tcaaacagtt gcccatactc
      841 cctgaaaaag aaattattga aataataact gcgcagaata gcgttggtac acctgcttta
      901 tttttggcta tgatgaacgg acatactgac aacgtgaaaa tatttatgca agaaattcag
      961 tcactggtag ataatcacat cattcatgaa gataatctgg ttaaattact gcaaactaaa
     1021 agtgctaacg aaacacctgg actttatatc tccatgttgt atggattcga tgaaataatc
     1081 gatatctttc tgaatgcatt aaccactcca atagcacaag agcttttaaa caaaaaactg
     1141 gtgatgagta ttttagccat gaaaatacat gatggtgagc caggattata cgccgcaatg
     1201 gaaaataatc accctttgtg tgtcacacgg ttcctctcta aaattaatgg catcgccttt
     1261 aaatacaagt tgagcaaagc taacatcatg gatttattaa aaggagctac agcacaggga
     1321 acccctgcat tatacatcgc catgagcaag ggtaatgaag acgtcgtgtt atcttatata
     1381 tcgacgctgg gtgcttttgc aaaaaaacat tcttttagtc aacatcagtt atttacacta
     1441 ttggccgcta aaaatcatga caacatgtca gctgttcata tagccattca tcataagcat
     1501 tataaaactg tagaaacata ttatgctgct attaatgcaa tcagccaaag cctgagtttt
     1561 agtgctgatg aaataaagac g
//
LOCUS       DAPHKZ010000278         1569 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.283, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000278 DAPHKZ010000000
VERSION     DAPHKZ010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1569
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.283"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..291
                     /locus_tag="RH288_004676"
     CDS             <1..291
                     /locus_tag="RH288_004676"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein"
                     /protein_id="HDV4033625.1"
                     /translation="HKQERNGKKRKRKKKRKRKKKKKKKKKKKKNNNKHGNHRKITSE
                     KNIPDTSQTGRVTGDASAWPASLPAGVSLPGVFARADRRPPPPALYHLFLLP"
     gene            complement(270..461)
                     /locus_tag="RH288_004677"
     CDS             complement(270..461)
                     /locus_tag="RH288_004677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033626.1"
                     /translation="MNISTETREILRNYKAVINARRREMGQKPLTTAQIVDEICDFVA
                     NQQAVFLGGQYILQGSRNR"
     gene            complement(461..880)
                     /locus_tag="RH288_004678"
     CDS             complement(461..880)
                     /locus_tag="RH288_004678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HDV4033627.1"
                     /translation="MYCTVKEIIRDVLDTDVPDSECVFAVVLTRGDVRHIAQDWSLTD
                     DELETVMQRLDDAFVYGACDRVVSDIVNELMEEKRVNRLVTVPAVLLEKVMVMAGSEI
                     YRLHAVGSENGGDGDAFVREEREIMRVMRQALDGENG"
     gene            complement(927..1229)
                     /locus_tag="RH288_004679"
     CDS             complement(927..1229)
                     /locus_tag="RH288_004679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV4033628.1"
                     /translation="MMPEYEGGFWHFIRLPDGGGYMMPDGDRFHMVNGANWFDRTVSA
                     DAAGVILTSLVINRQLWLYHDSGDAGLTQLYRMRDVQLWRHIEFHPECNAIYAALD"
BASE COUNT          417 a          448 c          395 g          309 t
ORIGIN      
        1 cataaacagg agaggaacgg aaagaagagg aagaggaaaa agaagaggaa gaggaaaaag
       61 aaaaagaaga agaagaagaa gaagaagaag aacaataaca agcacggtaa ccacagaaaa
      121 ataacatcag aaaaaaacat tccggacaca tcacaaacag gaagggtaac gggcgacgcg
      181 tcagcgtggc ccgcttccct tccggcaggc gtcagcctgc caggggtttt cgcgcgggct
      241 gacaggcggc ctccaccgcc tgccctgtat cacctgtttc tgctgccctg aaggatgtac
      301 tgaccgccga ggaatacagc ctgctgattc gccacaaaat cgcagatttc atcaacaatc
      361 tgcgccgtgg tgagcggttt ctgccccatt tcacgacgtc gtgcattaat cacagctttg
      421 taattacgca gaatttcgcg ggtttccgtg ctgatattca ttacccgttc tccccgtcca
      481 gcgcctgacg catcacccgc ataatctcac gttcttccct gacaaatgcg tcaccgtcgc
      541 ccccgttctc gctcccgaca gcatggaggc gataaatttc actaccagcc atcaccatca
      601 ctttttccag cagcaccgca gggactgtta caagacggtt tacgcgcttt tcctccatca
      661 gttcattgac aatatcggaa acaactctgt cacatgcgcc atatacaaaa gcatcgtcca
      721 gccgctgcat gacggtttcc agctcatcgt ctgtcagact ccagtcctgg gctatgtgac
      781 gcacatcccc acgggtcagc accacggcaa aaacgcattc actgtccggc acgtctgtat
      841 ccagtacatc gcgaatgatt tctttaacag tacagtacat gttctcgtct cctttacagg
      901 ggcggcattg ccgccccgtc cgttaatcag tccagtgccg cgtaaatcgc gttgcattca
      961 gggtgaaatt cgatgtgacg ccacaactgc acatcacgca tccggtaaag ctgagtcagc
     1021 cccgcatcac cgctgtcgtg gtacagccac aactgacggt taatcacaag ggaagtcaga
     1081 atgacacctg cggcatcagc actcacagta cggtcaaacc agtttgcacc gttcaccatg
     1141 tggaaacggt cgccatccgg catcatgtaa ccgccaccgt ccggcaggcg gatgaagtgc
     1201 cagaatccgc cttcatattc cggcatcatt tttttcgcca gcgcgtatac agacgcttcg
     1261 gcatacagaa aatcctggcc aaacaggtaa ggcagaaaag acagacggtc gcactcttca
     1321 acgttcagag tgacagattt cgcatattgc atgatgtttt cctccgttgt tcacatattc
     1381 cgcgacaccg ggcggtgccg tgcctccata aaagccgggc gataaggcgg ggatgcaggg
     1441 gcgcaaggga agccgcagcc tgacgcacac ggctgacggg agttggaggg tgagaccgcg
     1501 aaatctgagc gggtgaacga ccggaaaatc acggcagacg ggaagaaagg accgggtgac
     1561 cgcagcggc
//
LOCUS       DAPHKZ010000279         1563 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.284, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000279 DAPHKZ010000000
VERSION     DAPHKZ010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.284"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            103..540
                     /locus_tag="RH288_004680"
     CDS             103..540
                     /locus_tag="RH288_004680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV4033629.1"
                     /translation="MFYSPSLNIFVNPALKDDYINANSWPDDALAVSDDVYNEFAINT
                     PPDDKIRVAGKNGLPTWALIPPPSHEELIQQAESERQLLLNQANEYMNSKQWPGKAAI
                     GRLKGEELAQYNSWLDYLDALELVDTTGAPDIEWPTPPAVQAR"
     gene            complement(512..1114)
                     /locus_tag="RH288_004681"
     CDS             complement(512..1114)
                     /locus_tag="RH288_004681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV4033630.1"
                     /translation="MYNAILNNKFIATKAGEITVYNYDSETREYISASTEYLAVGVGI
                     PAYSCLDAPGTHKVGYAICRSADLNSWEYVPDHRGEVVYNTETGESKEITVPGDYPEN
                     TTTIVPLTPYDKWDGEKWVTDTEAQHSAAVDAAEAQRQSLIDAAMASISLIQLKLQAG
                     RKLTQAETTRLNAVLDYIDAVAATDTSTAPDVIWPELPEA"
     gene            complement(1114..>1563)
                     /locus_tag="RH288_004682"
     CDS             complement(1114..>1563)
                     /locus_tag="RH288_004682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001388200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV4033631.1"
                     /translation="GAAFSAEEYPELTKAYPTNKLPDLRGEFIRGWDDGRGVDAGRAL
                     LSLQNDSFEAHRHESFFYAGISRNETPLKNLPSSDEMLTLSSTTNALSPDSIDATNSL
                     IGNDDYNCLIEGNKNNKRTATGLSTSIVGAAETRPRNISFNYIVRAA"
BASE COUNT          413 a          366 c          341 g          443 t
ORIGIN      
        1 tgtcggcttc tgcaattaca tcaaatcagt tccgcggttt ttcaagcata gcgactgctg
       61 caaacgctgt attaggtcgt tatatcgcta taggggtgta atatgtttta tagtccatct
      121 ttaaacattt ttgtgaatcc tgcacttaag gatgattaca ttaatgcaaa ttcatggcca
      181 gatgatgctc ttgctgtcag tgatgatgtt tataatgaat ttgcaatcaa tacgcctcca
      241 gatgacaaaa ttcgtgttgc aggaaaaaat ggattaccca catgggcact aatacctcca
      301 ccatcacatg aagaacttat tcaacaggca gaatcagaaa ggcaattatt gcttaatcag
      361 gccaacgaat acatgaacag taaacaatgg cccggtaaag ccgctattgg tcgtctgaaa
      421 ggcgaggaac tggcgcaata taattcgtgg ctggattatc tggacgcact ggagctagtc
      481 gatactaccg gtgcgccaga tattgaatgg cctacgcctc cggcagttca ggccagatga
      541 catccggcgc ggtgctggta tctgttgccg ccaccgcgtc aatgtaatcc agcacggcgt
      601 taagtcgggt tgtttctgcc tgcgtcagct tccgcccggc ctgtaatttc agttgaatca
      661 gactgatgga agccattgca gcatcaatca gcgactggcg ctgtgcttct gccgcgtcta
      721 ctgcggcact atgctgtgcc tcagtatctg tcacccattt ctcaccatcc catttatcgt
      781 atggcgttaa cgggacgata gtggttgtat tttcagggta atcacccgga actgtgattt
      841 cttttgattc tcccgtttcg gtgttataga caacttcacc gcgatggtct ggcacatatt
      901 cccatgagtt taaatctgcc gaacggcaga ttgcataacc aaccttatgt gtgccaggag
      961 catctaaaca ggaatatgca gggataccga cacccacagc aagatattca gttgatgcag
     1021 aaatatactc ccgtgtctca ctgtcatagt tataaacggt aatctctcct gcctttgtgg
     1081 caataaattt attatttaag atggcgttat acatcatgca gccctcacaa tgtaattaaa
     1141 tgaaatatta cgtgggcgtg tctctgctgc accgacaata ctggtactca accccgttgc
     1201 cgttcgtttg ttatttttat ttccttcaat cagacagttg taatcatcat taccaattaa
     1261 cgaattggtg gcatcaatac tgtccgggga caaggcatta gttgtggaac ttaaagtcag
     1321 catctcgtct gaacttggaa gattttttaa tggtgtttca ttgcgtgaaa tacccgcgta
     1381 aaaaaaggac tcatgcctgt gagcttcaaa agagtcattc tgaagactta gcaaggctcg
     1441 ccccgcatcc actccacgtc catcatccca gccacgaata aattcaccgc gtaaatcagg
     1501 caatttattg gtcgggtaag cctttgtcag ttccgggtat tcttcagcag aaaaagccgc
     1561 acc
//
LOCUS       DAPHKZ010000280         1470 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.285, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000280 DAPHKZ010000000
VERSION     DAPHKZ010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1470
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.285"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>1470
                     /gene="rhsB"
                     /locus_tag="RH288_004683"
     CDS             <1..>1470
                     /gene="rhsB"
                     /locus_tag="RH288_004683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhs element protein RhsB"
                     /protein_id="HDV4033632.1"
                     /translation="RYGWTPRGELAVVYDRSGKQVRSFTYDDKYRGRMVAHRHTGRPE
                     IRYRYDSDGRVTEQLNPAGLSYTYQYEKDRITITDSLNRREVLHTQGEAGLKRVVKKE
                     HADGSVTQSQFDAVGRLKAQTDTAGRTTEYSPDVVTGLITRITTPDGRASAFYYNHHS
                     QLTSATGPDGLEMRRKYDESGRLIQETAPDGDITRYRYDNPHSDLPYATEDATGSRKT
                     MTWSRYGQLLSFTDCSGYVTRYDHDRFGQVTAVHREEGLSQYRAYDSRGQLIAVKDTQ
                     GHETRYEYNAAGDLTTVIAPDGSRNGTQYDAWGKAICTTQGGLTRSMEYDAAGRVIRL
                     TSENGSHTTFRYDVLDRLIQETGFDGRTQRYHHDLTGKLIRSEDEGLVTHWYYDEADR
                     LTHRTVKGETAERWRYDERGWLTDISHISEGHRVAVYYGYDEKGRLTGERQTVHHPQT
                     EALLWQHETRHAYNAQGLANRCIPDSLPAVEWLTYGSGYL"
BASE COUNT          360 a          422 c          460 g          228 t
ORIGIN      
        1 cgctatggct ggacgccgcg cggcgaactg gcggtggtgt atgaccgtag tggcaaacag
       61 gtgcgcagct ttacttacga tgataaatac cggggccgga tggtggcgca ccgtcacacg
      121 ggccggccgg aaatccgtta ccgttacgac agcgacgggc gggtgacaga acagctaaac
      181 ccggcaggct taagttacac gtatcagtat gagaaggacc gcatcaccat caccgacagc
      241 ctgaaccgcc gtgaagtgct gcacacgcag ggcgaagccg ggctgaagcg ggtggtgaaa
      301 aaggaacacg cggacggcag cgtcacgcag agtcagtttg atgcggtggg caggcttaag
      361 gcacagacag atacggcagg caggacaaca gagtacagcc cggatgtggt gacgggcctc
      421 atcacgcgca tcaccacgcc ggatggcagg gcatcggcgt tttactataa ccaccacagc
      481 cagttaacgt cagccaccgg gccagacggg ctggaaatgc gccgcaaata tgatgaatcc
      541 ggccgtctga ttcaggaaac tgcccctgac ggcgatatca cccgctaccg ttatgataat
      601 ccacacagtg acttacccta cgcaacggaa gatgccaccg gcagccggaa aaccatgacg
      661 tggagccgtt acggccagtt gctgagcttc accgactgtt ccggttatgt aacccgttat
      721 gaccatgacc gttttggtca ggtgacggcg gtgcaccgcg aggaagggct gagccagtac
      781 cgcgcatacg acagccgtgg acagttaatt gccgtgaaag acacgcaggg ccatgaaacg
      841 cggtatgaat acaacgccgc cggtgacctg accaccgtca ttgccccgga cggcagcaga
      901 aacgggacac agtacgatgc gtggggaaag gccatctgta ccacgcaggg cgggctgacg
      961 cgcagtatgg aatacgatgc tgccggacgg gtcatccgcc tgaccagtga aaacggcagc
     1021 cacaccacct tccgttacga tgtactcgac cggctgatac aggaaaccgg ctttgacggc
     1081 cgcacacagc gttatcacca cgacctgacc ggcaaactta tccgcagcga ggatgagggg
     1141 ctggtcaccc actggtacta tgacgaagca gaccgcctca ctcaccgcac cgtgaagggc
     1201 gaaaccgcag agcggtggcg gtatgacgaa cgcggctggc tgacagacat cagccatatc
     1261 agcgaagggc accgggtggc ggtgtattac ggatatgatg agaaaggccg gctgaccggt
     1321 gagcgtcaga cggtgcatca cccgcagacg gaagcactgc tctggcagca tgagaccaga
     1381 catgcgtaca acgcgcaggg gctggcgaac cgctgtatac cggacagcct gcccgccgtg
     1441 gaatggctga cctacggcag cggttacctg
//
LOCUS       DAPHKZ010000281         1452 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.286, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000281 DAPHKZ010000000
VERSION     DAPHKZ010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1452
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.286"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            827..1429
                     /gene="fimB"
                     /locus_tag="RH288_004684"
     CDS             827..1429
                     /gene="fimB"
                     /locus_tag="RH288_004684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimB"
                     /protein_id="HDV4033633.1"
                     /translation="MKNKADNKKRNFLTHSEIESLLKAANTGPHAARNYCLTLLCFIH
                     GFRASEICRLRISDIDLKAKCIYIHRLKKGFSTTHPLLNKEVQALKNWLSIRTSYPHA
                     ESEWVFLSRKGNPLSRQQFYHIISTSGGNAGLSLEIHPHMLRHSCGFALANMGIDTRL
                     IQDYLGHRNIRHTVWYTASNAGRFYGIWDRARGRQRHAVL"
BASE COUNT          426 a          258 c          327 g          441 t
ORIGIN      
        1 gagctttgca agctaactca gtgagcttgg tgaaaatcag tgtttacccg ccatcaggct
       61 gagcataatt ctcatcatga aatatgtttc ctggtttgtg gcttgtaact ggtcacttct
      121 gaagtcgatc tggagaggct tgttgatgtt ggtgttttca ggatgatgtt tcacttagtt
      181 tgtttgccgt atcgcccggc gaatggctgt gattgaggaa ggtttaagtc gtagtgacca
      241 aagctatatt taccaacgaa tgtagatgaa aaaatcatct cctgcgttcc cccatatctc
      301 caggataaaa aggaatgtaa caatctcatg gcgtaagctg acgaatcagc aggaataatc
      361 gctagggacc taagaattag catgataata gccactaaga aattactgcg ctccatgaaa
      421 tagccatttt gtggcaaatg gagttgacta ataatgtcat atgtgagacg gctagttgaa
      481 cgaatattaa attttgctga attttttatg ttgattttac ttgttacaga acatatcaca
      541 tgatatatag ataagattag ttgcattaat gatgagggtt attattagat tcgtatccga
      601 ttgataaata tataaaggta catagcatgc aagagcatgg cgtttgtatg gcaacgttat
      661 tataattaac agttgctact ccatttaagt tcactcagaa gaactggtcc acttacgtta
      721 gttattaagc aaacgttcgc ttttataaac ataatcagga taaaaatgtt ggattattgc
      781 taacccagca cagctagtgc gcgtctgtaa ttataaggga aaaacgatga agaataaggc
      841 tgataacaaa aaaaggaact tcctgaccca tagtgaaatc gaatcactcc ttaaagcagc
      901 aaataccggg cctcatgcag cacgtaatta ttgtctgact ttgctttgtt ttattcatgg
      961 tttccgggcg agtgaaattt gtcgattgag gatttcggat attgatctta aggcaaagtg
     1021 tatatatatc catcgattaa aaaaaggctt ttcaacaacg cacccgctat tgaataaaga
     1081 agttcaggct ttaaaaaact ggttgagtat ccgtacttcg tacccgcatg ctgagagcga
     1141 gtgggtattt ttatcacgta aggggaatcc gctttctcgg caacagtttt accatattat
     1201 ctcgacttcc ggtggtaatg ccgggttgtc actggagatt catccgcaca tgttacgcca
     1261 ttcgtgtggt tttgctttgg cgaatatggg aatagatacg cgacttatcc aggattatct
     1321 tgggcatcgc aatattcgtc atactgtctg gtataccgcc agcaatgcag ggcgttttta
     1381 cggcatctgg gatagagcca gaggacgaca gcgtcacgct gttttataga gatagttgag
     1441 ataccaggga tg
//
LOCUS       DAPHKZ010000282         1360 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.287, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000282 DAPHKZ010000000
VERSION     DAPHKZ010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1360
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.287"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..308
                     /locus_tag="RH288_004685"
     CDS             <1..308
                     /locus_tag="RH288_004685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV4033634.1"
                     /translation="PPDGKIRVAGENGLPTWALIPPPSYEELIQQAESERQLLLNQAN
                     EYMNSKQWPGKAAIGRLKGEELAQYNLWLDYLDALELVDTASAPDIEWPTPPAVQAR"
     gene            complement(280..882)
                     /locus_tag="RH288_004686"
     CDS             complement(280..882)
                     /locus_tag="RH288_004686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV4033635.1"
                     /translation="MNNAELNSELIATMAGEITVYNFDVMSREYISASTEYLAIGVGI
                     PAYSCLDAPGTYKAGYAICRSADFNSWEYVPDHRGEIVFSTETGESKEITAPGDYPDN
                     TTTIAPLTPYDKWDGEKWVTDTEAQHSAAVDAAEAQRQSLIDTAMASISLIQLKLQAG
                     RKLTQAETTSLNAVLDYIDAVTATDTSTALDVIWPELPEA"
     gene            complement(882..1340)
                     /locus_tag="RH288_004687"
     CDS             complement(882..1340)
                     /locus_tag="RH288_004687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HDV4033636.1"
                     /translation="MPVPWPSATPPTGWLKCNGAAFSAEEYPELAKAYPTNKLPDLRG
                     EFIRGWDDGRGVDNGRGLLTLQDGAIVSHNHYWGIWTSRTNDQTLESFTGTTILKQIT
                     PLSPSIDFDNYPIPNPAITEGGVVAATTKPAGANETRPRNVAFNYIVRAA"
BASE COUNT          346 a          327 c          324 g          363 t
ORIGIN      
        1 cgcccccaga tggcaaaatt cgtgttgcag gagaaaatgg attacccaca tgggcactaa
       61 tacctccacc atcatatgaa gaacttattc aacaggcaga atcagaaagg caattattgc
      121 ttaatcaggc caacgaatac atgaacagta aacaatggcc tggtaaagca gctattggtc
      181 gtctgaaagg tgaggaactg gcacaatata atttgtggct ggattatctg gacgcactgg
      241 agctggtcga taccgccagt gcgccagata ttgaatggcc tacgcctccg gcagttcagg
      301 ccagatgaca tccagcgcgg tgctggtatc tgttgccgtc accgcgtcaa tgtaatccag
      361 cacagcgtta aggctggttg tttctgcctg cgtcagttta cgtccggcct gcaatttcag
      421 ctgaatcaga ctgattgaag ccattgcagt atcaatcagt gactggcgct gtgcttctgc
      481 tgcatctact gcggcgctat gctgtgcttc ggtatccgtc acccatttct caccatccca
      541 tttatcgtat ggcgttaacg gggcgatagt ggttgtatta tcagggtaat cacccggagc
      601 tgtgatttct tttgattctc ctgtttcggt gctaaagacg atttcaccgc gatggtctgg
      661 tacatattcc catgagttaa aatctgcaga tcggcagatt gcataaccag ctttgtatgt
      721 gcctggggca tctaaacagg aatatgccgg aatgccgaca ccaatagcaa gatattcagt
      781 tgaagctgaa atatattccc gactcatgac atcaaagtta taaacagtaa tttctcctgc
      841 catagtggca attaattcac tgtttaattc tgcgttattc attatgcagc cctcacaata
      901 tagttaaaag cgacatttcg tgggcgtgtt tcattcgcac ctgcaggttt agtcgttgcc
      961 gcaacaacac caccctctgt aatagccggg ttgggaattg ggtaattatc gaagtcaata
     1021 gacggagaca ggggcgtgat ttgttttaaa atcgtggtgc ctgtaaaact ttccagagtc
     1081 tggtcgttag ttcgtgaagt ccagattccc caatagtggt tatgactgac aatagcaccg
     1141 tcctgaagcg ttaataatcc ccttccgtta tccactccac gcccgtcatc ccagccccga
     1201 ataaactcac cgcgtaaatc aggtaattta tttgtcgggt aagcctttgc cagttccggg
     1261 tattcttcag cagaaaaagc cgcaccgttg catttcagcc agcctgttgg cggagtggcg
     1321 gaaggccacg gaacaggcac gccaacgggt aatgctgagc
//
LOCUS       DAPHKZ010000283         1302 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.288, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000283 DAPHKZ010000000
VERSION     DAPHKZ010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1302
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.288"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            182..1302
                     /locus_tag="RH288_004688"
                     /pseudo
     CDS             182..1302
                     /locus_tag="RH288_004688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027427.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT          476 a          184 c          306 g          336 t
ORIGIN      
        1 tgaacaacac cagaaagaga aaaatataaa atacatacag aaagacatga gagcaaggga
       61 cggggcaggg caagatcatg aaaattgtga tgtaaatcac gattttcatc tttgctttaa
      121 cgcctacagg tgatcaaaat ttaacctttg gaataactaa aaagataaaa aaggacgcca
      181 ggtgagtatt caaagtttgc ttgattatat ttcagtgacc cctgatatac gacaacaagg
      241 aaaggttaaa cataaattat ctgctatttt gtttctcacc gtatgtgcag taattgcagg
      301 tgccgatgag tggcaggaaa ttgaagattt tggacatgaa agacttgaat ggctaaagaa
      361 atatggtgat tttgataatg gcattccggt cgatgacacc attgcacgcg ttgtgagtaa
      421 cattgacagt ttggcctttg aaaagatgtt tattgaatgg atgcaggagt gccatgaaat
      481 cactgatggt gaaattatag caatagatgg aaagaccata agaggctcct ttgataaggg
      541 aaaaagaaaa ggagcaatcc atatggtgag tgcattctcg aacgaaaatg gtgttgtact
      601 ggggcaggtg aaaacggaag ccaaaagtaa tgagattaca gccattccag agttgcttaa
      661 cctactgtat ttaaagaaaa atttgataac cattgatgct atgggctgtc agaaagatat
      721 cgcttcgaag atcaaagata aaaaagcaga ttatcttctg gcagtaaaag gcaatcaggg
      781 gaaattacat catgcattcg aggaaaaatt tcctgtaaat gtgttttcta attataaagg
      841 cgattcgttt agtacgcagg agataagtca tggaagaaaa gaaacacgtt tgcatattgt
      901 cagtaacgta acgcctgaac ttttgtgatt ttgaattcga atggaaggga ttaaaaaagc
      961 tttgtgtagc attgtcattc aggcagaaga aagaagataa atcagcagaa ggtgtaagca
     1021 tccgatatta tatttcatca aaggatatgg atgctaaaga atttgcacat gctatcagag
     1081 cgcactggct gatcgagcac agtcttcatt gggtgttaga tgtaaaaatg aatgaagatg
     1141 ccagccggat aagaagagga aacgcagcct aaataatatc tggaataaag aagatggcac
     1201 tgaatttatt aagagattgc aaagacatta agggtgaaga ggaaaagaaa gaaggctgcg
     1261 ttaaacacag ggaaagatca tcagaagttc actttttgta ct
//
LOCUS       DAPHKZ010000284         1289 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.289, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000284 DAPHKZ010000000
VERSION     DAPHKZ010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1289
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.289"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            71..>1289
                     /locus_tag="RH288_004689"
     CDS             join(71..395,395..>1289)
                     /locus_tag="RH288_004689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612175.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS2 family transposase"
                     /protein_id="HDV4033637.1"
                     /translation="MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAAS
                     QLFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVE
                     YGRAKKLDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWMDGRRSRHTDDTDV
                     LLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRVYRIMRQNALLLERKPAVP
                     PSKRAHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHWAVTTGGFN
                     SETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRS
                     PESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREY
                     LRQRACNGLSDNRCL"
BASE COUNT          327 a          307 c          379 g          276 t
ORIGIN      
        1 cagacaacca atatcactta aataagtgat agtcttaata ctagttttta gactagtcat
       61 tggagaacag atgattgatg tcttagggcc ggagaaacgc agacggcgta ccacacagga
      121 aaagatcgca attgttcagc agagctttga accggggatg acggtctccc tcgttgcccg
      181 gcaacatggt gtagcagcca gccagttatt tctctggcgt aagcaatacc aggaaggaag
      241 tcttactgct gtcgccgccg gagaacaggt tgttcctgcc tctgaacttg ctgccgccat
      301 gaagcagatt aaagaactcc agcgcctgct cggcaagaaa acgatggaaa atgaactcct
      361 caaagaagcc gttgaatatg gacgggcaaa aaagtggata gcgcacgcgc ccttattgcc
      421 cggggatggg gagtaagctt agtcagccgt tgtctccggg tgtcgcgtgc gcagttgcac
      481 gtcattctca gacgaaccga tgactggatg gatggccgcc gcagtcgtca cactgatgat
      541 acggatgtgc ttctccgtat acaccatgtt atcggagagc tgcccacgta tggttatcgt
      601 cgggtatggg cgctgcttcg cagacaggca gaacttgatg gtatgcctgc gatcaatgcc
      661 aaacgtgttt accggatcat gcgccagaat gcgctgttgc ttgagcgaaa acctgctgta
      721 ccgccatcga aacgggcaca tacaggcaga gtggccgtga aagaaagcaa tcagcgatgg
      781 tgctctgacg ggttcgagtt ctgctgtgat aacggagaga gactgcgtgt cacgttcgcg
      841 ctggactgct gtgatcgtga ggcactgcac tgggcggtca ctaccggcgg cttcaacagt
      901 gaaacagtac aggacgtcat gctgggagcg gtggaacgcc gcttcggcaa cgatcttccg
      961 tcgtctccag tggagtggct gacggataat ggttcatgct accgggctaa tgaaacacgc
     1021 cagttcgccc ggatgttggg acttgaaccg aagaacacgg cggtgcggag tccggagagt
     1081 aacggaatag cagagagctt cgtgaaaacg ataaagcgtg actacatcag tatcatgccc
     1141 aaaccagacg ggttaacggc agcaaagaac cttgcagagg cgttcgagca ttataacgaa
     1201 tggcatccgc atagtgcgct gggttatcgc tcgccacggg aatatctgcg gcagcgggct
     1261 tgtaatgggt taagtgataa cagatgtct
//
LOCUS       DAPHKZ010000285         1276 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.290, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000285 DAPHKZ010000000
VERSION     DAPHKZ010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1276
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.290"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            128..730
                     /locus_tag="RH288_004690"
     CDS             128..730
                     /locus_tag="RH288_004690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDV4033638.1"
                     /translation="MLAFCRSSLKSKKYIIILLALAAIAGLGTHAAWSSNGLPHIDNK
                     TLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFD
                     LYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNH
                     CLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH"
     gene            complement(769..1194)
                     /gene="nudI"
                     /locus_tag="RH288_004691"
     CDS             complement(769..1194)
                     /gene="nudI"
                     /locus_tag="RH288_004691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HDV4033639.1"
                     /translation="MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWAISGGGVEPGE
                     RIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSAN
                     REVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL"
BASE COUNT          355 a          286 c          267 g          368 t
ORIGIN      
        1 aaaattttga ggcattttgc cgacatcgta ggatttttaa tattacacca actgcgaatt
       61 atcgccagaa atgtagctca atttcacggt aattgtctgg ttgcgcttgt ctataggtgg
      121 agtttacgtg ttagcttttt gccgctcttc gttgaagtca aaaaaatata tcatcatttt
      181 actggcgctc gctgcaattg ccggactggg tactcatgcc gcctggagta gcaatggttt
      241 gccacatatc gacaataaaa cactggccag actggcacag cagcacccgg ttgtcgtttt
      301 gtttcgtcat gctgaacgtt gcgaccgttc aaccaatcaa tgcttgtcag ataaaacagg
      361 tattacggtt aaaggtaccc aggatgcccg tgaactgggc aacgctttta gtgctgatat
      421 ccctgatttc gatctttatt ccagtaatac cgtccggacc attcagtcgg ctacctggtt
      481 ttcagcgggt aaaaaattga cggtagataa acgacttctt cagtgcggta atgagattta
      541 tagtgcaatt aaggacttac aaagcaaagc gcctgataaa aatatcgtta ttttcaccca
      601 taatcattgc ctgacatata ttgctaaaga taagcgtgac gcgacattta aacctgatta
      661 tctggatggt ttagtcatgc atgtggaaaa aggcaaagtt tatctggatg gggaattcgt
      721 taaccactaa attttcaatc tgacagccag taatggctgt catcattgtt acagaagacc
      781 tttcaaacgt aacgtttttc gggtggcgac attcaaatca taatgcacca gatcttcagg
      841 ttttacccac gcgtagtcct gaaactcttc gtttattttc acttctcggt tggcagaaac
      901 gcagtcaaaa atcaggtaaa tcatataaat ctcttccttg cgaccatctg catacgtctt
      961 ggtgcgaata tcatcgctga aggtccacgg cgtgatttct gtcaaaagca gctgttctcc
     1021 cagttcttcg cgaatttcgc ggcgtagtgc ctcttcaatt cgttcgccag gctccacgcc
     1081 gccacccgaa atcgcccatt gaccggggaa aacgccgcga tcgtcggcca ttttacacag
     1141 caaataagca ccatcatttt gaatcaaagg gcatacaata gtccgttgtc gcacagggat
     1201 attccttata aataaaaaga aaccatgaga atacggtaac tcacaaatat gtgaaagtga
     1261 cagtaatctc ttttgc
//
LOCUS       DAPHKZ010000286         1270 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.291, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000286 DAPHKZ010000000
VERSION     DAPHKZ010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1270
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.291"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            59..1138
                     /gene="waaB"
                     /locus_tag="RH288_004692"
                     /gene_synonym="rfaB"
     CDS             59..1138
                     /gene="waaB"
                     /locus_tag="RH288_004692"
                     /gene_synonym="rfaB"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,6-galactosyltransferase"
                     /protein_id="HDV4033640.1"
                     /translation="MKIAFIGEAVSGFGGMETVIRDVITTFRQQHIQSEMFFFCRNDK
                     MDKGWLEGIKYSCSFSNIRLGFLRRAKHIHALSKWLQEYQPDIVICIDVISCLFAAKA
                     RKKSGIDMPVFSWPHFSLDHKKHAEYITCADYHLAISSGIKQQMINRGVAESTINVIF
                     NPVETKDSVIPAPEEGETATFIYVGRMKFEGQKRVKDLLDGLSQAKGNWKLHVLGDGS
                     DFEKCQAYGRELNIDDRIVWYGWQQYPWELVQQDIEKVSALLLTSSFEGFPMTLLEAL
                     SWGIPCISADCVSGPADIIQPDVNGHLYQPGDIAGFVTLLNKYIAGEIHIEHEKIPAS
                     IDEFYQSKYYDRLHKVIISAISRRK"
     gene            1138..>1270
                     /locus_tag="RH288_004693"
     CDS             1138..>1270
                     /locus_tag="RH288_004693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,3-galactosyltransferase"
                     /protein_id="HDV4033641.1"
                     /translation="MQQVFFQETEFLNSVIDYDHKVETENLCLDIAYGTDKNFLFGCG
                     "
BASE COUNT          384 a          219 c          269 g          398 t
ORIGIN      
        1 tttatagaca aataaaaccg ttaaaacagt gagttttact caattaatga gagtttctat
       61 gaaaatagcg tttatcggcg aagctgtttc tggatttggc ggcatggaaa ctgtcattcg
      121 tgatgttatt actaccttca ggcaacaaca tatccaaagt gaaatgtttt tcttttgtcg
      181 taatgacaaa atggataagg gatggctgga aggtattaaa tactcatgtt cattttccaa
      241 tattcgttta ggttttttgc gtcgggcgaa acatattcat gctctaagta aatggcttca
      301 ggagtaccaa ccagatatcg ttatttgtat tgatgtgatc tcctgcctgt ttgccgcaaa
      361 agcacgtaaa aaatcaggaa ttgatatgcc agtattttca tggccacatt tttctttaga
      421 tcacaaaaaa catgctgaat atatcacctg tgccgactat catttagcaa tcagctctgg
      481 cattaaacag caaatgatta atcgaggtgt agcagaatcg acgataaatg ttatttttaa
      541 tcccgtcgaa actaaagact cagtcattcc cgcgcccgag gaaggtgaaa cggcaacgtt
      601 tatttatgtt gggcgtatga aatttgaagg ccagaaaaga gttaaagacc tgcttgatgg
      661 cttatcacaa gcgaaaggta actggaaact ccatgtattg ggtgatggct ccgatttcga
      721 aaaatgccag gcttatggta gagaattaaa tattgatgat cgaattgtct ggtatggttg
      781 gcaacaatat ccctgggaat tggtccagca agatattgaa aaagtgagtg cgttattgct
      841 cacgtcatct tttgaaggtt tcccaatgac cctacttgaa gccttgtcgt gggggattcc
      901 ttgtatcagt gccgattgtg tctccgggcc tgctgacatt attcaacctg atgtcaatgg
      961 ccatctgtat caaccgggag atattgctgg ttttgtaact cttctaaata aatatatagc
     1021 aggtgaaatt catatcgaac atgaaaaaat tcctgcgtcg atcgatgaat tttaccaatc
     1081 gaagtattac gatagattac ataaggtaat tatttctgct atttcccgga ggaaataatg
     1141 cagcaggtgt ttttccagga aactgagttt cttaattcag ttattgatta tgatcataaa
     1201 gtagaaacag aaaatctttg tctggacatc gcttatggaa ctgacaaaaa ctttctattt
     1261 ggttgcggaa
//
LOCUS       DAPHKZ010000287         1232 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.292, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000287 DAPHKZ010000000
VERSION     DAPHKZ010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.292"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>1232
                     /locus_tag="RH288_004694"
     rRNA            <1..>1232
                     /locus_tag="RH288_004694"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          310 a          284 c          390 g          248 t
ORIGIN      
        1 aggatgacca gccacactgg aactgagaca cggtccagac tcctacggga ggcagcagtg
       61 gggaatattg cacaatgggc gcaagcctga tgcagccatg ccgcgtgtat gaagaaggcc
      121 ttcgggttgt aaagtacttt cagcggggag gaagggagta aagttaatac ctttgctcat
      181 tgacgttacc cgcagaagaa gcaccggcta actccgtgcc agcagccgcg gtaatacgga
      241 gggtgcaagc gttaatcgga attactgggc gtaaagcgca cgcaggcggt ttgttaagtc
      301 agatgtgaaa tccccgggct caacctggga actgcatctg atactggcaa gcttgagtct
      361 cgtagagggg ggtagaattc caggtgtagc ggtgaaatgc gtagagatct ggaggaatac
      421 cggtggcgaa ggcggccccc tggacgaaga ctgacgctca ggtgcgaaag cgtggggagc
      481 aaacaggatt agataccctg gtagtccacg ccgtaaacga tgtcgacttg gaggttgtgc
      541 ccttgaggcg tggcttccgg agctaacgcg ttaagtcgac cgcctgggga gtacggccgc
      601 aaggttaaaa ctcaaatgaa ttgacggggg cccgcacaag cggtggagca tgtggtttaa
      661 ttcgatgcaa cgcgaagaac cttacctggt cttgacatcc acggaagttt tcagagatga
      721 gaatgtgcct tcgggaaccg tgagacaggt gctgcatggc tgtcgtcagc tcgtgttgtg
      781 aaatgttggg ttaagtcccg caacgagcgc aacccttatc ctttgttgcc agcggtccgg
      841 ccgggaactc aaaggagact gccagtgata aactggagga aggtggggat gacgtcaagt
      901 catcatggcc cttacgacca gggctacaca cgtgctacaa tggcgcatac aaagagaagc
      961 gacctcgcga gagcaagcgg acctcataaa gtgcgtcgta gtccggattg gagtctgcaa
     1021 ctcgactcca tgaagtcgga atcgctagta atcgtggatc agaatgccac ggtgaatacg
     1081 ttcccgggcc ttgtacacac cgcccgtcac accatgggag tgggttgcaa aagaagtagg
     1141 tagcttaacc ttcgggaggg cgcttaccac tttgtgattc atgactgggg tgaagtcgta
     1201 acaaggtaac cgtaggggaa cctgcggttg ga
//
LOCUS       DAPHKZ010000288         1232 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.293, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000288 DAPHKZ010000000
VERSION     DAPHKZ010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.293"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            167..802
                     /locus_tag="RH288_004695"
     CDS             167..802
                     /locus_tag="RH288_004695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HDV4033642.1"
                     /translation="MKRLIMATMVTAILASSTVWAADNAPVAAQQQTQQVQQTQKTAA
                     AAERISEQGLYAMRDVQVARLALFHGDPEKAKELTNEASALLSDDSTEWAKFAKPGKK
                     TNLNDDQYIVINASVGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVM
                     ENQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN"
BASE COUNT          392 a          256 c          261 g          323 t
ORIGIN      
        1 gacaggaagc atattcctac aattgtaaga ctaaaatact tcttgcgata ataactacaa
       61 ctgtaagata accctttcaa aatgaccgtt gctctctgat ttctcatttc atgctcaccc
      121 aatatgatgg cggcgttttc taaaactgtt aaagaatgag gtaagtatga aacgtttaat
      181 tatggccacg atggtcacag caattctggc atcttcaact gtatgggctg ctgataatgc
      241 tccggtagcg gcacaacagc aaactcagca agttcagcaa acccagaaaa cggcagcggc
      301 agcagagcgt atctctgaac aaggtttata tgcgatgcgt gacgtgcagg tagcgcgcct
      361 ggctctgttt catggcgatc cagaaaaggc aaaagaactg accaatgaag cttccgcttt
      421 gctgtcagat gacagtaccg aatgggcaaa gttcgctaag ccaggtaaaa agaccaatct
      481 caatgatgac caatatattg tcattaatgc atctgtcgga atttctgaga gttatgtagc
      541 aactcccgaa aaagaagccg cgataaaaat tgccaatgaa aaaatggcga aaggggataa
      601 aaagggcgca atggaagagc ttcgcctggc cggtgttggc gtaatggaaa accaatatct
      661 gatgccactt aaacagactc gtaatgcact tgctgatgcg cagaaactgc ttgataaaaa
      721 gcaatactac gaggcaaacc tggcgcttaa aggtgcggaa gatggaatca tcgtcgatag
      781 cgaagcactg tttgtgaact aatgctgaca ggcagtatat tgaggtaaag gatttaactc
      841 cctccagccg acaatttttt atgaccacaa tacgacaggt tgtggtcaaa aaattatttg
      901 gcgctcgcgg tgctataaac tcgcatttta tattcctcaa agtaaaccgc aataatcccg
      961 tgtcatcaca aatcatttat tatgttatgt tttatggtac gctttaaaaa gcgtaatcat
     1021 acccttgctt gtaaatcacc ggcgcttctt acagttgtaa gaataacatc acaaatgtcg
     1081 cgactctctc tgattaccac gaatcaatat ttatcatatt cttcttttcg tcctcactac
     1141 ttaccatgca gaaaggaatt ggaagtggcg atgaaatgat tttcagcact tgatacagga
     1201 ttttaaaaat atcgagtgca gctacgacga ta
//
LOCUS       DAPHKZ010000289         1222 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.294, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000289 DAPHKZ010000000
VERSION     DAPHKZ010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.294"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            286..588
                     /locus_tag="RH288_004696"
     CDS             286..588
                     /locus_tag="RH288_004696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV4033643.1"
                     /translation="MMPEYQGGFWHFIRLPDGGGYMMPDGDRFHMVNGANWFDRTVSA
                     DAAGIILTSLVINRQLWLYHDSGDAGLTQLYRMRDAQLWRHIEFHPECNAIYAALD"
     gene            635..1057
                     /locus_tag="RH288_004697"
     CDS             635..1057
                     /locus_tag="RH288_004697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HDV4033644.1"
                     /translation="MYCTVKEIIREVLDTDVPDSECVFAVVLTRGDVRHIAQDWNLPD
                     DELETVMQRLDDAFEHGADVSVVHDVVRELMEEKRVSRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLQALDGEHMS"
     gene            1054..>1222
                     /locus_tag="RH288_004698"
     CDS             1054..>1222
                     /locus_tag="RH288_004698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033645.1"
                     /translation="MNISTETREILRNYKAVINARRREMGQKPLTTAQIVDEICDFVV
                     NQQAVFLGGHYI"
BASE COUNT          269 a          311 c          372 g          270 t
ORIGIN      
        1 cccgctcaga tttcgcggtc tcaccctcca actcccgcca gccgtgtgcg tcaggctgcg
       61 gcttcccttg cgccctgtgc atccccgcct tatcgcccgg cttttatgga ggcacggcac
      121 cgcccggtgt cgcggaatat gtgaacaacg gaggaaaaca tcatgcaata tgcgaaacct
      181 gtcactctga acgttgaaga gtgcgaccgt ctctcctttc taccgtatct gtttggcaac
      241 gattttctgt atgccgaggc gtatgtgtac gcgctggcgc aaaaaatgat gccggaatat
      301 cagggaggct tctggcactt catccgcctg ccggacggtg gcggttacat gatgccggat
      361 ggcgaccgtt tccacatggt gaacggtgca aactggtttg accgtaccgt gagtgctgat
      421 gccgcaggca tcattctgac ttcccttgtg attaaccgcc agttgtggct gtaccacgac
      481 agcggtgatg caggactgac ccagctttac cggatgcgcg atgcgcagtt gtggcgtcac
      541 atcgaatttc accctgaatg caacgcgatt tacgcggctc tggactgatt aacggacggg
      601 gcggcaatgc cgcccctgta aaggagacga gaaaatgtac tgtactgtta aagaaattat
      661 ccgcgaagtg ctggatacag acgtgccgga cagtgaatgc gtttttgccg tggtgctgac
      721 ccgtggggat gtgcgtcaca tagcccagga ctggaacctg ccagacgatg agctggaaac
      781 cgtcatgcag cggctggacg atgcctttga gcatggtgcg gatgtcagcg ttgttcacga
      841 cgttgttcgt gaactgatgg aagaaaagcg cgtcagccgt caggtgacag tcccggcggt
      901 gatgctggaa aaagtgatgg cgctggcagg cagtgaaatg aagcgcctgt atgccgtcgg
      961 gagtgagaac gggggcgacg gtgacgcatt cgtcagggaa gaacgcgaag cgatggacgt
     1021 tgtgttacag gcgctggacg gggagcacat gtcatgaata tcagcacaga aacccgcgaa
     1081 attctgcgca attacaaagc cgtgattaat gcgcggcgtc gtgaaatggg gcagaaaccg
     1141 ctcaccactg cgcagattgt tgatgaaatc tgcgattttg tggtgaacca gcaggcggtt
     1201 ttcctcggtg gtcactatat cc
//
LOCUS       DAPHKZ010000290         1209 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.295, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000290 DAPHKZ010000000
VERSION     DAPHKZ010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1209
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.295"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            30..>1209
                     /locus_tag="RH288_004699"
     CDS             join(30..354,354..>1209)
                     /locus_tag="RH288_004699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612175.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDV4033646.1"
                     /translation="MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAAS
                     QLFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVE
                     YGRAKKLDSARALIARRWGVSLVSRCLRVSRAQLHVILRRTDDWKDGRRSRHSDDTDV
                     LLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRIYRIMRQNALLLERKPAVP
                     PSKRAHTGRVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHWAVTTGGFN
                     SETVQDVMLGAVERRFGNELPASPVEWLTDNGSCYRANETRQFARMLGLEPKSTAVRS
                     PESNGIAESFVKTIKRDYISVMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREY
                     LR"
BASE COUNT          302 a          290 c          362 g          255 t
ORIGIN      
        1 tagtttttag actagtcatt ggagagcaga tgattgatgt cttaggaccg gagaaacgca
       61 gacggcgtac tacacaggaa aagatcgcta ttgttcagca gagttttgaa ccgggaatga
      121 cggtctccct tgttgcccgg caacacggtg tggcagccag ccagttattt ctctggcgca
      181 agcaatacca ggagggaagt cttactgctg tggccgcagg agaacaggtc gttcctgcct
      241 ctgaacttgc tgctgccatg aagcagatta aagaactcca gcgcctgctc ggcaaaaaaa
      301 cgatggaaaa tgaactcctt aaagaagccg ttgaatatgg gcgtgcaaaa aagtggatag
      361 cgcacgcgcc cttattgccc ggcgatgggg agtaagctta gtcagccgtt gtctccgggt
      421 gtcgcgtgcg cagttgcacg tcattctcag acgaaccgat gactggaaag atggtcgccg
      481 cagccgtcac tcagatgata cggatgtgct tctccgtata caccatgtta tcggagagct
      541 gcccacgtat ggttatcgtc gggtatgggc gctgcttcgc agacaggccg aacttgatgg
      601 tatgcctgcg atcaatgcca aacgtattta ccggatcatg cgccagaatg cgctgttgct
      661 tgagcgaaaa cctgctgtac cgccatcgaa acgggcacat acaggcagag tggctgtgaa
      721 agaaagtaat cagcgatggt gctctgacgg gttcgagttc cgctgtgata acggagaaaa
      781 actgcgagtc acgttcgcgc tggactgctg tgaccgtgag gcactgcact gggcggtcac
      841 tacgggcggc ttcaacagtg aaacagtaca ggacgtcatg ctgggagcgg tggaacgccg
      901 cttcggcaac gagcttccgg cgtctccagt agagtggctg acggataatg gttcatgcta
      961 ccgggctaat gaaacacggc agtttgcccg gatgttgggg cttgaaccga agagcacggc
     1021 ggtgcggagt ccggagagta acggcatagc agagagcttc gtgaaaacga taaagcgtga
     1081 ctacatcagt gtcatgccca aaccagacgg gttaacggca gcaaagaacc ttgcagaggc
     1141 gttcgagcat tataacgaat ggcatccgca tagtgcactg ggttatcgct cgccacggga
     1201 atatctacg
//
LOCUS       DAPHKZ010000291         1209 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.296, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000291 DAPHKZ010000000
VERSION     DAPHKZ010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1209
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.296"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            138..245
                     /locus_tag="RH288_004700"
     CDS             138..245
                     /locus_tag="RH288_004700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033647.1"
                     /translation="MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG"
     gene            complement(298..1056)
                     /locus_tag="RH288_004701"
     CDS             complement(298..1056)
                     /locus_tag="RH288_004701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HDV4033648.1"
                     /translation="MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTTMTWYGHTTAWSLWGNASNTSSNDERSSEKYAAGG
                     RSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DKYTDNASETQPLGYASGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHF
                     GLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM"
BASE COUNT          339 a          291 c          279 g          300 t
ORIGIN      
        1 tatttttttc ataaaacgca gaaacagtga ccatgtgcac aacgccaccc gacggctgta
       61 ataacaaaaa atcccttgat gcctgtccct tttgttacac tccgttatca cgcacaagag
      121 atatgcagga cactggtatg ccgactaaac gctttgataa aaaacactgg aagatggtgg
      181 tggtgctact ggcaatctgt ggcgctatgt tgttgctacg ttgggcagca atgatttggg
      241 gctgagcagt gacaaacgaa gacagccaga ccgcataaca cggtccggca gataatttta
      301 catgctgtag cccagcgata aggttgtccg acggtcggta tgttccggtg cagactctgg
      361 aggttcagag ttccatgtga cgttgtaagc caccttcagt ccaaaatgtt cattaatagc
      421 aacatttaat gcgctttcgg agttcagcgt tgtgtcttcc gcgccaaaga ccgaaacacc
      481 ctgcgtaaat ttagcgttgt cagtcaactg ccatgcataa gccccggagg catagcccag
      541 cggctgggtt tcactggcat tgtcggtata tttgtcgtaa cgcacacctg gaccgaattc
      601 aaagcggaaa ctgtgtaccg ggccattcaa aaactgacga ccataacccg cggtcaacac
      661 atcgcgctct cgatagccgt tataacggtc tgtcagccag cttgcctgac caaataaata
      721 gtcataatca gttaaattaa aacggctacg cccgcccgcc gcatattttt ctgaagaacg
      781 ctcatcatta gaagaagtat tactggcgtt cccccacagc gaccaggcag tggtgtgtcc
      841 ataccaggtc atggtggtgt cagccgtaag tgaggagctt ttcgtattgc ctgattgtgc
      901 aagatatcct gcgttcagat taccttcgaa aggtttttta gcgctggcag gatcatccat
      961 gacagtaaaa acggaatcat cggcagctgc attcagtgac gcaaacatgc cccccgccaa
     1021 cataacgatg gcaggaactg tcttcaaaag cttcatttat caagagtccg tacaacaaaa
     1081 aaagagacca tcgcggtccc ggaaactttc ttaaggatca aagattagcg tccctggaaa
     1141 ggtaacgaat tataaaaagg cgcgaataac ttagcaatgt attcttattt cattttttga
     1201 ataagcatg
//
LOCUS       DAPHKZ010000292         1208 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.297, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000292 DAPHKZ010000000
VERSION     DAPHKZ010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1208
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.297"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            23..>1208
                     /gene="gltS"
                     /locus_tag="RH288_004702"
     CDS             23..>1208
                     /gene="gltS"
                     /locus_tag="RH288_004702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDV4033649.1"
                     /translation="MILDASYTLLVACIALLIGMFVVKFTPFLQKNHIPEAVVGGFIV
                     AIVLLIIDKTSGYSFTFDASLQSLLMLTFFSSIGLSSDFSRLIKGGKPLVLLTIAVTI
                     LIAIQNTVGMSMAVMMNESPFIGLIAGSITLTGGHGNAGAWGPILADKYGVTGAVELA
                     MACATLGLVLGGLVGGPVARHLLKKVSIPKTTEQERDTIVEAFEQPSVKRKINANNVI
                     ETISMLIICIVVGGYISALFKDTFLQLPTFVWCLFVGIIIRNTLTHVFKHEVFEPTVD
                     VLGSVALSLFLAMALMSLKFGQLASMAGPVLIIIAVQTVVMVLFACFVTFKMMGKDYD
                     AVVISAGHCGFGMGATPTAIANMQTVTKAFGPSHKAFLVVPMVGAFIVDISNSILIKI
                     FIE"
BASE COUNT          330 a          222 c          253 g          403 t
ORIGIN      
        1 gtaaactaat agaggtaaaa aaatgatcct agatgccagt tatacattat tagtcgcatg
       61 tatcgcgcta ctcataggaa tgtttgtcgt aaaatttacc ccgttcctac aaaaaaacca
      121 cataccagaa gccgtcgttg gtggctttat tgttgcaatt gttctgttaa ttattgataa
      181 aacatcaggt tattcgttta cttttgatgc ttcattgcaa agtttattaa tgctcacatt
      241 cttttcctct atcgggctaa gttctgactt ttctcgactg attaaaggag gaaagccgtt
      301 agttctatta actattgcag taacgatcct aatcgccatt caaaatactg tcggcatgag
      361 tatggctgtc atgatgaatg aaagtccatt tattggctta attgcaggtt caattactct
      421 aacaggtggt catggtaatg ccggagcatg gggccctatt ctcgctgata aatatggtgt
      481 aacaggcgcc gttgaattag cgatggcttg tgcaacactt ggattagtgt tgggtggttt
      541 agttggcggc cctgttgccc gtcatctttt gaaaaaggtc tctattccta aaacaaccga
      601 gcaagagcgc gacactatcg ttgaagcttt tgagcaacca agcgtcaaaa gaaaaatcaa
      661 tgcaaataac gttattgaaa ccatttcaat gctgattatc tgtattgttg ttggtggcta
      721 tatcagtgca ttgtttaaag atacttttct gcaactgcct acttttgtct ggtgtttatt
      781 tgtcggtatt attatccgta atacactgac tcatgtattt aaacacgaag tgtttgagcc
      841 gaccgtcgat gtattaggta gcgttgcttt atcgcttttc ttggcaatgg cgttaatgtc
      901 attaaaattt ggtcaattgg caagcatggc agggccagta ttaattatca ttgctgtaca
      961 aactgttgtc atggtgctat ttgcctgctt tgtcaccttc aaaatgatgg gcaaagatta
     1021 tgatgctgtc gtgatcagcg cgggtcactg tggctttggt atgggagcaa caccaacagc
     1081 aattgcgaat atgcaaacag tcacaaaagc atttggacca tcacataaag ctttccttgt
     1141 cgttcctatg gtcggtgcct ttattgttga tatttcaaac agtatcttaa ttaaaatatt
     1201 tattgaaa
//
LOCUS       DAPHKZ010000293         1205 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.298, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000293 DAPHKZ010000000
VERSION     DAPHKZ010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1205
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.298"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>1205
                     /locus_tag="RH288_004703"
     CDS             <1..>1205
                     /locus_tag="RH288_004703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HDV4033650.1"
                     /translation="IEPTAKELMGKDINYEVLVSKDGLYSWRRITLINPLYYVYFCRK
                     ITAPATWEIITEKFKSFESNDLFTCSSIPVRKDNSSNIAASVMNWWEDFEQKSLALAL
                     EYEFMFSTDISNFYPSIYTHSFEWVFISKEEAKKKKSKNNPGGLIDSHIQMMMNNQTN
                     GIPLGSTLMDTFAELILGQIDIELRKKTNELKIINYKVVRYRDDYRIFSNSKDDLDII
                     SKCLVNVLGDFGLDLNSKKTELYEDIILHSLKQAKKDYIKEKRHKSLQKMLYSIYLFS
                     LKHPNSKTTVRYLNDFLRNLFKRKTIKDNGQQVDAMLGIISSIMAKNPTTYPVGTAIF
                     SKLLSFLYGDDTQKKLTKLEQLHKKLDKQPNTEMLDIWFQRTQAKINLEWNKSYKSAL
                     CVRINDELT"
BASE COUNT          469 a          227 c          192 g          317 t
ORIGIN      
        1 attgaaccaa ccgccaagga gctgatgggt aaagatatca attatgaggt gcttgtcagt
       61 aaagatggtc tatatagctg gcgtaggata acacttatca atccccttta ttatgtctac
      121 ttctgtagaa aaatcacagc accagcaacc tgggaaatca taacagaaaa attcaaatct
      181 tttgaatcaa acgacctttt tacatgttca agcatccccg tcagaaaaga caactcgtca
      241 aacattgctg catctgtaat gaattggtgg gaagattttg aacaaaaaag ccttgccctt
      301 gctcttgaat acgaattcat gttcagcact gacatctcaa acttctaccc atcaatatat
      361 actcatagtt ttgaatgggt attcatatca aaagaagagg caaagaagaa aaaaagcaaa
      421 aataacccag gaggattaat tgacagccac attcaaatga tgatgaacaa ccagacaaat
      481 ggtattccac tcggcagcac attgatggat acatttgctg agcttatctt gggtcaaatc
      541 gatatagaat taagaaaaaa aactaacgaa ctcaaaataa taaactacaa ggtagtacgc
      601 taccgtgatg attaccggat cttctctaat agcaaagatg atttagacat aatatcaaaa
      661 tgtttagtca atgtattggg cgattttggt ttagatctaa actcaaaaaa aactgaacta
      721 tatgaagaca tcatacttca ttcgttgaaa caagctaaaa aagactacat caaagaaaaa
      781 agacataagt cactccagaa aatgctctat tcaatatatt tattttcact taaacatcca
      841 aactcgaaaa caaccgttag atatctaaat gattttctta ggaatttatt taagcgaaag
      901 acaattaaag ataacggcca acaggttgat gctatgcttg gtattatttc aagcatcatg
      961 gcaaaaaacc ctacaacgta cccagtagga acggcaattt tctcaaaact cctcagtttt
     1021 ctttatggtg atgacaccca aaaaaaatta acaaagctag aacaactcca taaaaaactg
     1081 gataaacaac ccaatacaga aatgcttgac atatggtttc agcgaactca agcaaaaata
     1141 aacctagagt ggaataaatc ttataagtca gctctatgcg tccgtataaa tgatgaactc
     1201 acaaa
//
LOCUS       DAPHKZ010000294         1197 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.299, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000294 DAPHKZ010000000
VERSION     DAPHKZ010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1197
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.299"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..165)
                     /locus_tag="RH288_004704"
     CDS             complement(<1..165)
                     /locus_tag="RH288_004704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5507 domain-containing protein"
                     /protein_id="HDV4033651.1"
                     /translation="MLVSKSNGFNASAVLGSGSYNENKSSKHMELLAHSILKLICKEA
                     ASETYRGALET"
     gene            complement(915..990)
                     /locus_tag="RH288_004705"
     tRNA            complement(915..990)
                     /locus_tag="RH288_004705"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(955..957),aa:Ile,seq:cat)
BASE COUNT          364 a          251 c          208 g          374 t
ORIGIN      
        1 agtttcaaga gcaccgcgat acgtctctga tgcagcttcc ttacaaatta attttaaaat
       61 actatgagct agtagctcca tgtgtttaga agatttattt tcattataac ttccactacc
      121 caaaactgcg ctagcgttaa atccgttgct tttactaact aacattgtct attcctcaat
      181 taatgtctac atggctattt ttaatgttat tactgtttgt cactataaaa aaacgctcat
      241 ttgagacaat tactgacatt aactgcttca cttgctacgc atggaacttt taattaaatt
      301 agcacaggaa tgttaaattt aataaacaaa aggttatttc gctgtatgat aaaaaaaccg
      361 ttataattta ttagtgaaaa tcgtttttca agtgttagaa atttatatct caatagcgtt
      421 ggttaatgag catagccacg ctcctgtaac gctcacaaaa ctcatctgcc tgcggcgggt
      481 gttctggtca gtagtagatg tttaaggcgt ggcagagaca tttcatcctt actctacggc
      541 attgttctac atacattggt tgtggtactc acttatcatc agtgagcgaa cagagaatag
      601 ttcagtgatt tgagtaatta acctgattaa atgaaggggt ataataaatg ataatactct
      661 ggctttatcg ttaattactt aattccacat gtaagcaatt tgcccgcttg gcatagcagg
      721 cattttttcc aggtactttt gaatgagtac tgatggataa atacattgca gtggcgtgcc
      781 acgtaccaaa acaccagccc tcattcgaaa ccacccaccg cacttcttcc ttgaaatggc
      841 gttagtcatg aaatatagac cgccatcgag taccccttgt acccttaact cttcctgata
      901 cgtaaataat gatttggtgg cccttgctgg acttgaacca gcgaccaagc gattatgagt
      961 cgcctgctct aaccactgag ctaaagggcc ttgagtgtgc aataacaata cttataaacc
     1021 acgcaataaa catgatgatc atatgatgta aataacagat ttttatgcgt tcccattcac
     1081 cttgggtcgt gattacacgc gacataaaac ccgacaccgc ctccattcgc aaagtcgata
     1141 ctcgcagtca acaagcaaat gttaataatt agcactatct atagttatca tcgattc
//
LOCUS       DAPHKZ010000295         1196 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.300, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000295 DAPHKZ010000000
VERSION     DAPHKZ010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1196
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.300"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..505)
                     /gene="sfmF"
                     /locus_tag="RH288_004706"
     CDS             complement(<1..505)
                     /gene="sfmF"
                     /locus_tag="RH288_004706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria assembly protein"
                     /protein_id="HDV4033652.1"
                     /translation="MRRVLFSCFCGLLWSSIGWAADPLGTININLHGNVVDFSCTVNT
                     ADIDKTVDLGRWPTTQLLNAGDTTALVPFSLRLEGCPPGSVAILFTGTPASDTNLLAL
                     DDPAMAQTVAIELRNSDRSRLALGEASPTEEVDANGNVTLNFFANYRALASGVRPGVA
                     KADAIFMI"
     gene            complement(516..>1196)
                     /gene="fimH"
                     /locus_tag="RH288_004707"
     CDS             complement(516..>1196)
                     /gene="fimH"
                     /locus_tag="RH288_004707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415066.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrin D-mannose specific adhesin FimH"
                     /protein_id="HDV4033653.1"
                     /translation="LVDSVMDIQFPPQNYIRMGTDPNVSQNLPFGVMDSRLIFRLKVI
                     RPFINMVEIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQIVEFDF
                     GDIGASLFSAAGPGNRPAGVMPQTKSIAVKCTNVAAQAYLTMRLEASAVSGQAMVSDN
                     QDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPTEGPFSAL
                     GYLRVDYQ"
BASE COUNT          326 a          321 c          269 g          280 t
ORIGIN      
        1 tgatcataaa tatcgcatcc gctttcgcca cacctggccg aacaccgctg gctaacgctc
       61 gataattggc aaaaaagttt agtgtgacat tgccatttgc atctacttcc tcagtcgggc
      121 tcgcctcccc cagtgcgagc cgggagcgat cgctattacg taattcgatg gcgacggttt
      181 gtgccattgc gggatcatcc agagccagca ggttggtatc ggatgccggc gttcccgtaa
      241 ataaaatcgc aactgaaccc ggaggacatc cctccagccg caggctaaaa gggacgagtg
      301 ccgtggtatc gccagcgttc agtaattgtg tcgtaggcca tctgcctaaa tctaccgtct
      361 tatcaatatc cgctgtgttt acggtacagg agaaatcaac aacgttaccg tgcaaattga
      421 tattaatcgt tcctaaaggg tcagctgccc atccaatgga actccacagt aacccgcaga
      481 aacagctaaa gagtactctt ctcattctcc gtacctcatt gataatcgac gcgtaaatac
      541 cccagcgcgc taaacggccc ctcggtcggt ttttgaccgg taatactgat aggccaggcg
      601 cgaagtgtga cattggctgc cgcagctgca tccagacgga aaggaataac gctattgaga
      661 tcgttaggcg taatcggcgt atcgttctga tcggcgacaa taaaacctaa atcctgattg
      721 tccgacacca tcgcctgacc agaaacggca ctggcttcca gacgcattgt taaataagcc
      781 tgcgcagcaa cattcgtaca tttgaccgca atgctcttgg tttgcggcat gacgccagct
      841 ggtcgattcc ccggccctgc cgcactaaat aacgatgcgc cgatatcacc aaaatcaaat
      901 tcaacaatct gcccggcatt taattcgcag ttttgcggca cttcaacccg gccaccaaaa
      961 ctaatggtat aaacaggtgt aaccaacgga tcgtaaggcg ttgatgtcac atacacggta
     1021 aacatcacct gtctggggat ctccaccatg ttaataaagg gacgaataac ctttaaacga
     1081 aatattaaac gagaatccat caccccgaat ggaaggtttt gcgaaacgtt aggatctgtt
     1141 cccatcctaa tataattttg cggggggaac tgaatatcca tcacactatc aaccag
//
LOCUS       DAPHKZ010000296         1156 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.301, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000296 DAPHKZ010000000
VERSION     DAPHKZ010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.301"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..892)
                     /gene="tdcA"
                     /locus_tag="RH288_004708"
     CDS             complement(<1..892)
                     /gene="tdcA"
                     /locus_tag="RH288_004708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HDV4033654.1"
                     /translation="MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIIND
                     IEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFG
                     FPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
                     QDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAV
                     WSKNYRIKKAASVLVELAKEY"
BASE COUNT          369 a          252 c          213 g          322 t
ORIGIN      
        1 aatactcttt ggctaattcc accaaaaccg atgctgcttt tttaatacga taatttttcg
       61 accataccgc ggcatattgt gccacaggta atgtttcttc aaccggaata gtaataaatt
      121 gattagaacc aaaaggtgac gtcatatcac aaggaattac agttaagaaa tcagcattga
      181 gaacaagatt ataaattgtc acgactgagt cggttttaac gatgttttca atactgatgc
      241 catttctttg taacgtagta agcagttcgc tgtagtaccc catattagtt tgtggcaaca
      301 cccactgttc gttcttcaac gactccagcg tggtggtgcc ggtgcatgtt cgggacttac
      361 tggctaccag cacaaactcg gactcgaaca gcggctcaac atgtaaatcc tgaagcttca
      421 tttctgcact taacgtacca atcgcaaaat ccagtcgacc gtcgcggatt gccggtaaga
      481 acgaagacag ttgcgcttca tacatagaaa cctgcgcttt cgggaacacc tctttgaact
      541 tgttgatcat ccctgacata aaagtaaaac caatcaatga aggaaaacca aatgagactt
      601 ccaccaccgc ctcagaagac ataccgctta tctcattaac catatttttc atttcacggg
      661 taatggattc ggaacgggag agtaacaatt gaccggcagg tgttaatgtt acaccggtat
      721 ttttccgcac cactaattcc acaccaaaat aatcttcaat atcgttaatg attttactga
      781 cggccggttg agttaaccct aattcttttg cagccgagcc gatagaacca cttctaatga
      841 cttcctgaaa gactaccagg tgctgcgttt tcggaagaag aatagtgctc ataacgacct
      901 acgttaatta cctcattgac ggcatgaagt gtatcaaaat gaaatgaaca ggatatgtgc
      961 gaccactcac aaattaactt tcaatacttt ccagagtatc gttattacaa ttaaatacct
     1021 ttaaatatca acaagttaaa gtataaaaat cagcataaac cctgattttt gtcaaaaaaa
     1081 atgacgggga taaccatatt ttatggcgat aacatcattc gttatgtggt taatacaaaa
     1141 aaggggctga gaccat
//
LOCUS       DAPHKZ010000297         1147 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.302, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000297 DAPHKZ010000000
VERSION     DAPHKZ010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1147
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.302"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..1117
                     /locus_tag="RH288_004709"
                     /pseudo
     CDS             1..1117
                     /locus_tag="RH288_004709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961353.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="DUF5507 domain-containing protein"
BASE COUNT          392 a          164 c          224 g          367 t
ORIGIN      
        1 agttggtgaa aataacttaa aggtattcaa cgtacacttt aataataatc acgagttagt
       61 tagttctggt gagcctgacg taatatgttt aagcaagcag gtctgggaaa atcttctcat
      121 taaactaaag ctggaaaaca atgaaaatgt gttttctgaa actaaaaaat tatcgaataa
      181 aaataatgcc gatcagtttt ttgaatgcgc taaaagaaat gaatagaacc ttttcgataa
      241 tataagaaaa agtgattttc atgttggttt acttaagcca agtagtacgc gtagtgttat
      301 tttagaaacg ccgccaaatg tctgtatgga atcacgtaat tcatatgaaa acaaaataga
      361 tgagatttca tctttgtcag agtcaaagga acaccccata gatattcaag aaaaaaaaga
      421 tgcgtttgtg aatgagttca agggggtatt atttgataaa aatacaaggt cttcagagct
      481 tctgtttaat ttttatgagt gttgctataa gtttttacca agagctcagc ctcaagataa
      541 aatcgatagc tataattcag cactgcaagc tttttccatt ttttgttcat ctacgttgac
      601 acataataat ataggctttg atttcaaatt atttcctgaa gtcaagctgt ctggagaaca
      661 tcttgaaacg gtattcaaat acaaaaatgg cgatgatgtc cgggagatag ccaaaattaa
      721 cattactctc caaaaagaag agggtggttt atataattta cgtggattgg attttaaggg
      781 gtgcttcttt tctggacaga acttcagtaa ctatgatatt caatatgtga actggggaac
      841 gtcattgttt gatgttgata ctccgtgtat ttttaatgcg cctgcttaca acaagagtaa
      901 tgaaaaatca ttaaaacctg tgagcgaaaa cggtttaagt ggagtattga ctgatcgtaa
      961 taataaaata aaactcatca cgggcgtggc accattcgat gatattttat ttatggatga
     1021 tgactttgat gatagttcct ctgaggatga tcccgttgag aatagtcctg ttgtgactag
     1081 tcccgttgta tcaagttcta aaagcagttt tcaatgatta ataaatggca atttttacaa
     1141 agagata
//
LOCUS       DAPHKZ010000298         1133 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.303, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000298 DAPHKZ010000000
VERSION     DAPHKZ010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.303"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..329)
                     /locus_tag="RH288_004710"
     CDS             complement(<1..329)
                     /locus_tag="RH288_004710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033655.1"
                     /translation="MADKAILWALISASTKEGRKACSLSYFACKAAEAELGLAYMAAN
                     DNKEFLTSLSNIMRYKIDAGLSESYTCYLLSKGKIIRPYLKNLNPLQLAADCIETVNK
                     IKDKNKK"
     gene            complement(1036..>1133)
                     /locus_tag="RH288_004711"
     CDS             complement(1036..>1133)
                     /locus_tag="RH288_004711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDV4033656.1"
                     /translation="AVNNGNIDAKSKLQELKKLKRMDRRKNKENP"
BASE COUNT          321 a          234 c          194 g          384 t
ORIGIN      
        1 ttttttttat tcttatcttt tattttattt actgtttcaa tgcaatcagc ggcaagttgg
       61 agtggattta gatttttcag atatggtctt atgatctttc ccttacttaa taaatagcat
      121 gtataggatt cggaaagtcc agcatctatt ttgtacctca ttatattaga taaggatgtg
      181 agaaattcct tgttatcatt cgcagccata tatgccagtc cgagttcagc ctctgcggcc
      241 ttacaggcaa aatagcttag tgaacacgct tttcgtccct ctttagtact ggctgatatt
      301 agtgcccata atattgcttt gtctgccaaa tctaactctc tctgaaattg tcttgcagta
      361 actgcactcg cagaaataga gaaaaaaata caattgttaa taaccttgcc atatttttta
      421 gtccgtaact gttaatgtgc tatctggctc tgaaaatatt aactcattta atttttgcat
      481 gtcattagat aaaccagtta tacaaccctc ggaacagaat cgaggtccta aagacggacc
      541 aaaagcgttt aaacaactat gtattgaaaa tccattgcga ttataagttc ctgtattaac
      601 tgacggtact aatcgtatgc cgtcaggttt tctattgctt gctcccgggt cattaacatt
      661 ccaactccat aggccttgag gtattggcca tctatttata aatgtgtaca acggggatta
      721 tttttacatt gcatattatt accagaagcg actggaatac taagcacatc ataaaaatta
      781 tcatcacatg gtatatctga aacacacgaa agcataccta aagttatgct gtataaacag
      841 gtggctaatc ccaaggggat cgattccaga aatcgggttc aacggatact gataaaaatt
      901 ccacctacct tccagcccaa tcggagcctg agtgttatac cgcccctgct gcggttaatg
      961 ttaccgataa tagttatagt acagccctga ttcatcatca tactactgct gcggcagtct
     1021 gatgaactat tgcttttacg gattctcctt attcttcctt ctatccattc gctttagctt
     1081 tttgagctct tgaagtttgc tctttgcatc aatattaccg ttatttacag cga
//
LOCUS       DAPHKZ010000299         1131 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.304, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000299 DAPHKZ010000000
VERSION     DAPHKZ010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1131
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.304"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>1131
                     /locus_tag="RH288_004712"
     rRNA            <1..>1131
                     /locus_tag="RH288_004712"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          309 a          242 c          361 g          219 t
ORIGIN      
        1 tataatgggt cagcgactta tattctgtag caaggttaac cgaatagggg agccgaaggg
       61 aaaccgagtc ttaactgggc gttaagttgc agggtataga cccgaaaccc ggtgatctag
      121 ccatgggcag gttgaaggtt gggtaacact aactggagga ccgaaccgac taatgttgaa
      181 aaattagcgg atgacttgtg gctgggggtg aaaggccaat caaaccggga gatagctggt
      241 tctccccgaa agctatttag gtagcgcctc gtgaattcat ctccgggggt agagcactgt
      301 ttcggcaagg gggtcatccc gacttaccaa cccgatgcaa actgcgaata ccggagaatg
      361 ttatcacggg agacacacgg cgggtgctaa cgtccgtcgt gaagagggaa acaacccaga
      421 ccgccagcta aggtcccaaa gtcatggtta agtgggaaac gatgtgggaa ggcccagaca
      481 gccaggatgt tggcttagaa gcagccatca tttaaagaaa gcgtaatagc tcactggtcg
      541 agtcggcctg cgcggaagat gtaacggggc taaaccatgc accgaagctg cggcagcgac
      601 gctgatgcgt tgttgggtag gggagcgttc tgtaagcctg cgaaggtgtg ctgtgaggca
      661 tgctggaggt atcagaagtg cgaatgctga cataagtaac gataaagcgg gtgaaaagcc
      721 cgctcgccgg aagaccaagg gttcctgtcc aacgttaatc ggggcagggt gagtcgaccc
      781 ctaaggcgag gccgaaaggc gtagtcgatg ggaaacaggt taatattcct gtacttggtg
      841 ttactgcgaa ggggggacgg agaaggctat gttggccggg cgacggttgt cccggtttaa
      901 gcgtgtaggc tggttttcca ggcaaatccg gaaaatcaag gctgaggcgt gatgacgagg
      961 cactacggtg ctgaagcaac aaatgccctg cttccaggaa aagcctctaa gcatcaggta
     1021 acatcaaatc gtaccccaaa ccgacacagg tggtcaggta gagaatacca aggcgcttga
     1081 gagaactcgg gtgaaggaac taggcaaaat ggtgccgtaa cttcgggaga a
//
LOCUS       DAPHKZ010000300         1099 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.305, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000300 DAPHKZ010000000
VERSION     DAPHKZ010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.305"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            27..554
                     /locus_tag="RH288_004713"
     CDS             27..554
                     /locus_tag="RH288_004713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV4033657.1"
                     /translation="MKGGWNFYQYPLNPVQYIDSMGLASKYGHLNNGGYGARPNKPPT
                     PDPSKLPDIAKQLRLPYPIDQASSAPNVFKTFFRALSPYDYTLYCRKWVKPNLTCTPQ
                     DDSQYPGMDTKTASDYLPQTNWPTTQLPPGYTCAEPYLFPDINKPDGPATAGIDDLGE
                     ILAKMKQRTSRGIRK"
     gene            551..>1099
                     /locus_tag="RH288_004714"
     CDS             551..>1099
                     /locus_tag="RH288_004714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033658.1"
                     /translation="MKRVLFFLLMIFVSFGVIADCEIQAKDHDCFTIFAKGTIFSAFP
                     VLNNKAMWRWYQNEDIGEYYWQTELGTCKNNKFTPSGARLLIRVGSLRLNENHAIKGT
                     LQELINTAEKTAFLGDRFRSYIRAGIYQKKSSDPVQLLAVLDNSIMVKYFKDEKPTYA
                     RMTAHLPNKNESYECLIKIQHEL"
BASE COUNT          369 a          204 c          239 g          287 t
ORIGIN      
        1 ggtatatcac tcaggatccg attgggctga aggggggatg gaatttttat cagtatccgc
       61 tgaatccggt tcagtatata gattcaatgg gactggcatc aaaatatgga cacttaaata
      121 atggcggata tggagcgaga cccaacaaac cgcctacgcc cgatccaagt aaattgccgg
      181 acatagcgaa acaattaaga ctgccatatc ctattgacca ggccagtagt gcgcctaatg
      241 ttttcaaaac attcttcaga gcattaagcc cttacgacta cacactgtat tgcaggaagt
      301 gggtaaaacc aaatctgact tgtacgccac aggatgattc ccagtatcca gggatggata
      361 caaagacagc aagtgattac ctgccacaga caaattggcc aacaactcaa ttaccaccag
      421 gatatacttg tgcagaaccc tatttattcc cagacattaa taaacccgat gggccagcaa
      481 cagcagggat agatgatttg ggtgaaattt tagctaagat gaaacagaga acatcgagag
      541 gaataagaaa atgaaaagag ttttgttctt tttgctgatg atatttgtta gttttggtgt
      601 tatagctgat tgcgaaatac aagctaaaga tcatgattgt tttactattt tcgctaaggg
      661 tactattttt tccgcgtttc ctgtcttaaa taataaagcc atgtggagat ggtatcagaa
      721 tgaggacatc ggtgagtatt attggcaaac agaactgggt acatgtaaaa ataataaatt
      781 cacaccaagc ggggcgagac tcttaattcg cgtcgggtca ctacgcctta atgaaaatca
      841 tgccatcaaa ggaacgttgc aggagttgat aaatacagca gaaaaaacgg cgtttctcgg
      901 cgatcggttt agaagttata taagagcggg tatctatcaa aaaaagagca gtgatccagt
      961 tcagttgttg gcagtccttg ataattcaat catggtaaaa tattttaaag atgagaaacc
     1021 aacttatgct cgaatgacag cacatctccc gaacaaaaat gagtcttacg aatgtttaat
     1081 aaagatacag catgaacta
//
LOCUS       DAPHKZ010000301         1083 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.306, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000301 DAPHKZ010000000
VERSION     DAPHKZ010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1083
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.306"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..936
                     /locus_tag="RH288_004715"
     CDS             <1..936
                     /locus_tag="RH288_004715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element IS421 family transposase"
                     /protein_id="HDV4033659.1"
                     /translation="VTAWAQLHDVATLSDVALLKRLRNAADWFGILAAQTLAVRAAVT
                     GCTSGKRLRLVDGTAISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFAQ
                     TADEIRIADRGFGSRPECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGLD
                     CGKNGETTVMIGNSGNKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQAE
                     TLEAAGHVLLLTSLPEDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPELA
                     KAWIFANLLAAFLIDDIIQPSLDFPPRSAGSEKKN"
BASE COUNT          277 a          260 c          295 g          251 t
ORIGIN      
        1 gtcactgcat gggctcagct ccatgacgtt gcaacattat ctgacgtggc tctcctgaag
       61 cggctgcgga atgccgccga ctggtttggc atacttgccg cacaaacact tgctgtacgc
      121 gccgcagtta cgggttgtac aagcggaaag agattgcgtc ttgtcgatgg aacagcaatc
      181 agtgcgcccg ggggcggcag cgctgaatgg cgactacata tgggatatga tcctcatacc
      241 tgtcagttca ctgattttga gctaaccgac agcagagacg ctgaacggct ggaccgattt
      301 gcgcaaacgg cagacgagat acgcattgct gaccggggat tcggttcgcg tcccgaatgt
      361 atccgctcac ttgcttttgg agaagctgat tatatcgtcc gggttcactg gcgaggattg
      421 cgctggttaa ctgcagaagg aatgcgcttt gacatgatgg gttttctgcg cgggctggat
      481 tgcggtaaga acggtgaaac cactgtaatg ataggcaatt caggtaataa aaaagccgga
      541 gctccctttc cggcacgtct cattgccgta tcacttcctc ccgaaaaagc attaatcagt
      601 aaaacccgac tgctcagcga gaatcgtcga aaaggacgag tagttcaggc ggaaacgctg
      661 gaagcagcgg gccatgtgct attgctaaca tcattaccgg aagatgaata ttcagcagag
      721 caagtggctg attgttaccg tctgcgatgg caaattgaac tggcttttaa gcggctcaaa
      781 agtttgctgc acctggatgc tttgcgtgca aaggaacctg aactcgcgaa agcgtggata
      841 tttgctaatc tactcgccgc atttttaatt gacgacataa tccagccatc gctggatttc
      901 ccccccagaa gtgccggatc cgaaaagaag aactaactcg ttgtggagaa taacaaaaat
      961 ggtcatctgg agcttacagg tggccattcg tgggacagta tccctgacag cctacaaaac
     1021 gcaattgaag aacgcgaggc atcgtcttaa cgaggcaccg aggcgtcgca ttcttcagat
     1081 ggt
//
LOCUS       DAPHKZ010000302         1068 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.307, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000302 DAPHKZ010000000
VERSION     DAPHKZ010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1068
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.307"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(190..345)
                     /locus_tag="RH288_004716"
     CDS             complement(190..345)
                     /locus_tag="RH288_004716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033660.1"
                     /translation="MREYPNGEKTHLTVMAAGFPSLTGDHKVIYVAADRHVTSEEILE
                     AAIRLLS"
     gene            complement(425..490)
                     /locus_tag="RH288_004717"
     CDS             complement(425..490)
                     /locus_tag="RH288_004717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033661.1"
                     /translation="MKAPSGAFLLGVYSMDTHILR"
     gene            complement(493..681)
                     /locus_tag="RH288_004718"
     CDS             complement(493..681)
                     /locus_tag="RH288_004718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDV4033662.1"
                     /translation="MTNHIHFRCPCCHGSQYRTSSFDVSDMNPFGAKCIFCKSMMITF
                     DNISQYLNASRLSLDLKK"
     gene            complement(692..904)
                     /gene="cspI"
                     /locus_tag="RH288_004719"
     CDS             complement(692..904)
                     /gene="cspI"
                     /locus_tag="RH288_004719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspI"
                     /protein_id="HDV4033663.1"
                     /translation="MSNKMTGLVKWFNPEKGFGFITPKDGSKDVFVHFSAIQSNDFKT
                     LTENQEVEFGIENGPKGPAAVHVVAL"
BASE COUNT          362 a          212 c          181 g          313 t
ORIGIN      
        1 taagttttca atattcatca tttcctcttt tagtctgtta tgactttcca gttacacagt
       61 aagtcgatta tatggtgcaa acgtgtaaaa gataagatga aacatcgcaa taatcaacat
      121 acgatagtct aaattttaca caaacagaca aagagaattt tcctgaatta tcaatgcaat
      181 agcatcaaat caactcaaga gccttattgc tgcttccaga atttcttctg aagtaacatg
      241 tcgatccgcg gctacataaa tgactttatg atctccggtc agagatggaa accctgcggc
      301 cattacagta aggtgtgttt tttcgccatt tggatattca cgcatgatgg tgttaactcc
      361 agtcatcgct ggcactacca ctgctggttc agagttaaaa aaaactatga tttttttcat
      421 gatgttaccg tagtatgtga gtatccatcg aatagacacc aagcaaaaaa gctcccgaag
      481 gagccttcat tttcactttt tcaaatccaa cgacagacgg ctggcattta agtattgtga
      541 aatattatca aatgtaatca tcattgattt acaaaagata cattttgccc cgaaaggatt
      601 catgtcagaa acatcaaaag atgatgttct atactgggaa ccatgacaac acgggcatct
      661 aaagtgaata tggtttgtaa tattgtctac ctcaaagcgc cactacatga acagcggcag
      721 gacctttagg tccgttctca ataccaaatt caacttcctg attctcagtt aatgttttga
      781 aatcgttgct ctgaattgct gagaaatgga caaacacatc tttgctgcca tctttcggcg
      841 tgatgaaacc aaaacctttt tcagggttaa accatttcac taaaccagtc attttgttag
      901 acataattat taccttttga agaaattagc ccttgggcag aatggtccga aaaaaaatct
      961 cagagagaaa aaccaacaag gaaatctcaa gaggtacaaa taataaaatt ataacaatga
     1021 ctgcttcaga taaatttgta acaaaccaga acaccattaa cgcatgat
//
LOCUS       DAPHKZ010000303         1049 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.308, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000303 DAPHKZ010000000
VERSION     DAPHKZ010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.308"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(72..956)
                     /gene="xapR"
                     /locus_tag="RH288_004720"
     CDS             complement(72..956)
                     /gene="xapR"
                     /locus_tag="RH288_004720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XapR"
                     /protein_id="HDV4033664.1"
                     /translation="MERVYRTDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKE
                     LENQLGTQLFIRHSRSVVLTHAGKILMEESRRLLVNANNVLARIEQIGRGEAGRIELG
                     VVGTAMWGRMRPVMRRFLRENPNVDVLFREKMPAMQMALLERRELDAGIWRMATEPPT
                     GFTSLRLHESAFLVAMPEEHHLSSFSTVPLEALRDEYFVTMPPVYTDWDFLQRVCQQV
                     GFSPVVIREVNEPQTVLAMVSMGIGITLIADSYAQMNWPGVIFRPLKQRIPADLYIVY
                     ETQQVTPAMVKLLAALTQ"
BASE COUNT          282 a          281 c          227 g          259 t
ORIGIN      
        1 tgcgatttgc gaaattgcct gatgcgcttc acttagcaga ctactatttc cggcaattcc
       61 tgtctcctca cctactgtgt caatgcagcc aacagcttaa ccatcgcggg cgtcacctgc
      121 tgtgtttcat aaacaatata taaatctgca gggatgcgct gtttgagcgg acggaaaatg
      181 acacctggcc agttcatttg tgcgtagctg tccgctatca atgtgatacc aatgcccata
      241 ctgaccatag cgagtaccgt ttgcggttca ttaacttcgc gaataacaac cggtgaaaat
      301 cccacctgct ggcaaactcg ctgcaaaaaa tcccagtcag tgtaaacggg cggcattgta
      361 acaaaatact cgtcacgtag cgcttccagc gggacggtgg aaaatgatga gagatgatgc
      421 tcttcaggca tcgccaccag aaacgccgat tcatgcaacc gtaagctggt aaaaccagtc
      481 ggtggttctg tcgccattcg ccagatcccg gcatcaagtt cgcggcgttc cagcaaggcc
      541 atttgcatcg cgggcatctt ttcgcgaaaa agaacgtcaa cgttaggatt ttccctaagg
      601 aatcgccgca taaccgggcg catccgtccc cacattgccg ttcccactac gccgagttca
      661 atccgccctg cttctccccg acctatttgt tcaatccgag ccaatacatt attagcattc
      721 accagcaatc gacgcgattc ttccatcaag attttgcccg cgtgtgtcag tacgacgctg
      781 cgcgaatggc gaataaaaag ctgcgtgccg agttgatttt ccagctcttt aatatgaatg
      841 ctgagcggag gctgagacat atttaaacgc gctgctgcgc ggccaaaatg caactcttcc
      901 gctacggcaa gaaaataacg gagcaactta agatctgttc tgtatacgcg ttccataatt
      961 aagtgctcca tataataaat acatcgtatt aaattatcat ggcataaagt atttcaccac
     1021 cagatatccg acatacataa acacaatgg
//
LOCUS       DAPHKZ010000304          925 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.309, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000304 DAPHKZ010000000
VERSION     DAPHKZ010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..925
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.309"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>925
                     /locus_tag="RH288_004721"
     CDS             <1..>925
                     /locus_tag="RH288_004721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HDV4033665.1"
                     /translation="IQNDRTRIQTIYQPGSFTPLIRVETATGELAKTQRRSLADALQQ
                     SGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVEQMQNQMDPVYT
                     PARKIHLYHCDHRGLPLALISTEGATAWCAEYDEWGNLLNEENPHQLQQLIRLPGQQY
                     DEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLYGYQLNPISDIDPLGLSMWEDAK
                     SGACTNGLCGTLSAMIGPDKFDSIDSTAYDALNKINSQSICEDKEFAGLICKDNSGRY
                     FSTAPNRGERKGSYPFNSPCPNGTEKVSAYHT"
BASE COUNT          247 a          230 c          261 g          187 t
ORIGIN      
        1 atacagaacg acagaacccg catccagacg atttatcagc cggggagctt cacgccactc
       61 atcagagttg aaaccgccac cggtgagctg gcgaaaacgc agcgccgcag cctggcggat
      121 gcgcttcagc agtccggcgg cgaagacggt ggcagtgtgg tgttcccgcc ggtgctggtg
      181 cagatgctcg accggctgga aagtgaaatc ctggctgacc gggtgagtga ggaaagccgc
      241 cgctggctgg catcgtgcgg cctgaccgtg gagcagatgc aaaaccagat ggacccggtg
      301 tacacgccgg cgcgaaaaat ccacctgtac cactgcgacc atcgcggcct gccgctggcg
      361 ctcatcagca cggaaggggc aacagcgtgg tgcgcagaat atgatgaatg gggcaacctg
      421 ctgaatgaag agaacccgca tcagctgcag cagcttatcc ggctgccggg gcagcagtat
      481 gatgaggagt ccggcctgta ttacaaccgc caccgctatt atgacccgct gcaggggcga
      541 tatatcactc aggatccgat tggactgaag gggggatgga acctgtatgg atatcaattg
      601 aatccgatat cagacatcga ccccctgggt ttatctatgt gggaggatgc aaaatcgggg
      661 gcatgtacta atggtctttg cggcacacta tccgctatga taggtccaga taaatttgat
      721 tctatagata gcaccgcata tgacgcctta aataaaataa atagccaatc tatttgcgaa
      781 gataaagagt tcgctggttt aatatgtaag gataatagtg gcagatattt ctcaacagca
      841 cctaaccgag gagaaagaaa aggatcatat ccattcaata gcccttgccc taatggtact
      901 gagaaagtat cagcttatca tactc
//
LOCUS       DAPHKZ010000305          917 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.310, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000305 DAPHKZ010000000
VERSION     DAPHKZ010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.310"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..171
                     /locus_tag="RH288_004722"
     CDS             <1..171
                     /locus_tag="RH288_004722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB family protein"
                     /protein_id="HDV4033666.1"
                     /translation="VSRELYPVVHVGDESWRMMTTDMASVPVSVIGEEVADLSHREND
                     IKNAINLMFWGI"
     gene            172..>917
                     /locus_tag="RH288_004723"
     CDS             172..>917
                     /locus_tag="RH288_004723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HDV4033667.1"
                     /translation="MSGSVIHSQSAARVPAVYSAGQSPQLPVVIDYPAALALRQMSMV
                     HDELPKYLLAPEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLAPPYPF
                     VQLATLKQRTEKAARTAGRTPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPLERRNKR
                     TGRTEKARIWEVTDRTVRTWIGEAVAAAATDGVTFSVPVTPHTFRHSHAMHMLYAGIP
                     LKVLQSLMGHKSISSTEVYTKVFALDVAAR"
BASE COUNT          200 a          251 c          272 g          194 t
ORIGIN      
        1 gtctcccgtg agctttaccc ggtggtgcat gtcggggatg aaagctggcg catgatgacc
       61 accgatatgg ccagtgtgcc ggtctccgtt atcggggaag aagtggctga tctcagtcac
      121 cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct ggggaatata aatgtcaggc
      181 tccgttatac acagccagtc tgcagccagg gtaccggcag tgtattctgc cggacagtct
      241 ccacaacttc ctgttgtcat tgattatccg gcagctctgg cacttcgcca gatgtcgatg
      301 gttcatgatg aactgccgaa atatctgctg gctccggaag tgagtgccct gctccattac
      361 gtcccggatc tgcgccgcaa gatgctgctg gccacactgt ggaacaccgg tgcgcgcatt
      421 aatgaagcac tggcgctgac gcggggggat ttttcgcttg cgcctccgta tccgtttgtg
      481 cagctggcca ctctgaagca gcggaccgaa aaagccgcca ggacggcagg aagaacgcct
      541 gccggacagc agactcaccg gctggttccg ctctccgact cctggtacgt cagtcagctg
      601 cagacgatgg tggcaacact gaaaattcct ctggaacggc gtaataaacg aacaggcagg
      661 acagagaaag cgcggatctg ggaagtgacg gacagaacgg tcaggacctg gattggggag
      721 gcggttgccg ccgctgctac tgacggtgtg acgttctctg tcccggtcac gccacatacg
      781 ttccgccatt cccatgcgat gcacatgctg tatgccggta taccactgaa ggtcctgcag
      841 agcctgatgg ggcataagtc catcagctca acggaggtct acacgaaggt gtttgcgctg
      901 gatgtggctg cacggca
//
LOCUS       DAPHKZ010000306          912 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.311, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000306 DAPHKZ010000000
VERSION     DAPHKZ010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..912
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.311"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..221
                     /locus_tag="RH288_004724"
     CDS             <1..221
                     /locus_tag="RH288_004724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YbbC/YhhH family protein"
                     /protein_id="HDV4033668.1"
                     /translation="KTETMAIQLAEIYVRYRYGERIAEEEKPYLITELPDSWVVEGAK
                     LPYEVAGGVFIIEINKKNGCVLNFLHSK"
     gene            221..502
                     /locus_tag="RH288_004725"
                     /pseudo
     CDS             221..502
                     /locus_tag="RH288_004725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001434876.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS domain-containing protein"
     gene            590..>912
                     /locus_tag="RH288_004726"
     CDS             590..>912
                     /locus_tag="RH288_004726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001448399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033669.1"
                     /translation="MKRLNLGGTDQFFHCMAFCRVSKLNDAGVSRSAKGLGYEKEIRD
                     YGLNLFGMYGRKVKLSHSEMIEDNKKDLAVNDHGLTCPSTTDCSDRCSDYINPEHKKT
                     IKALQ"
BASE COUNT          298 a          139 c          243 g          232 t
ORIGIN      
        1 taaaaactga aacaatggcg atacaattag ctgaaatata tgttaggtat cgctatggcg
       61 aacggattgc agaagaagaa aaaccatatt taattacgga actaccagat agttgggttg
      121 ttgagggagc aaagttacct tatgaagttg cgggtggtgt atttattata gaaattaata
      181 agaaaaatgg atgtgttttg aatttcctac atagtaaata atgctggcgc tgatggatgc
      241 ggatggaaac attgcgtgga gcggggagta tgatgagtgg ggcaaccagc tgaatgaaga
      301 gaacccgcat cacctgcacc agccgtaccg gctgccgggg cagcagtatg ataaggagtc
      361 ggggctgtac tacaaccgga accggtacta cgatccgttg caggggcggt atatcactca
      421 ggacccgata gggctggagg ggggatggag tctgtatgcg tatccgctga atccggtgaa
      481 tggtattgat ccattagggt taagtcccgc agatgtagcg ctaataagaa gaaaagatca
      541 actaaaccat caaagagcat gggatatatt atctgatact tatgaagata tgaagagatt
      601 aaatttaggt gggactgatc aatttttcca ttgtatggca ttttgtcgag tgtctaaatt
      661 aaatgacgct ggtgttagcc gatcggcgaa agggctgggt tatgaaaaag agattagaga
      721 ttacgggtta aatctgttcg gtatgtacgg cagaaaagta aagctatccc attctgaaat
      781 gattgaagat aataaaaaag acttggctgt aaatgaccat gggttgacat gtccatcaac
      841 aacagattgc tcagatagat gtagtgatta tattaatcca gagcataaaa aaacgataaa
      901 ggctttacaa ga
//
LOCUS       DAPHKZ010000307          902 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.312, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000307 DAPHKZ010000000
VERSION     DAPHKZ010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.312"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(140..>902)
                     /locus_tag="RH288_004727"
     CDS             complement(140..>902)
                     /locus_tag="RH288_004727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV4033670.1"
                     /translation="HFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNEENPHHLHQ
                     PYRLPGQQHDEESGLYYNRHRHYDPLQGRYITPDPIGLRGGWNMYQYPLNPIQVIDPM
                     GLDAIENMTSGGLIYAVSGVPGLIAANSITNSAYQFGYDMDAIVGGAHNGAADAMRHC
                     YLMCRMTKTFGSTIADVIGKNHEAAGDRQGQPAKERIMDLKNNTVGIACGDFSAKCSD
                     ACIEKYNTGQLFGLDGIKADNPIKAKQGSSDASNY"
BASE COUNT          238 a          229 c          173 g          262 t
ORIGIN      
        1 atttttttca gaaagatata tctcaacgct ctttggtgtt ttatgtccat aaaatacgat
       61 gtcagaattt gaattgttat caaacccaag gtaaacaaca aataaacaaa gggtaattaa
      121 aaaaatgaca agtttgcctc taataatttg aagcatctga actcccttgc tttgctttta
      181 ttggattatc tgcttttata ccatctaacc cgaagagttg cccagtgtta tatttttcaa
      241 tacatgcatc gctacatttg gcagaaaaat cgccacaagc aataccgaca gtgttatttt
      301 taagatccat gattctttct ttagctggct gaccttgtct atcccctgcc gcctcatgat
      361 ttttacctat cacgtcagct attgttgatc caaatgtctt agtcattcga cacatcaagt
      421 aacaatgtct cattgcatcg gcggccccat tatgagctcc gccaacaata gcatccatat
      481 cataaccgaa ctggtaagca ctgttagtaa tgctgtttgc agcaatcaat ccaggtacac
      541 cagatacggc ataaattagt ccacctgatg tcatattctc aatcgcatct aaccccattg
      601 ggtctatcac ttgtatggga ttcaacggat actgatacat attccatcca cctctcaacc
      661 caatcgggtc cggggtgata taccgcccct gcaacggatc gtagtgccgg tgacggttat
      721 agtacagccc cgactcctca tcatgctgct gccctggcag acggtacggc tggtgcaggt
      781 gatgcgggtt ctcctcatta agctggttgc cccattcatc atactccccg cgccacgccg
      841 tattgccgtc ttcgctgatg agcgccagcg gcaggccccg gtggtcgcag tggtaaaaat
      901 ga
//
LOCUS       DAPHKZ010000308          897 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.313, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000308 DAPHKZ010000000
VERSION     DAPHKZ010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.313"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            69..>897
                     /locus_tag="RH288_004728"
     CDS             69..>897
                     /locus_tag="RH288_004728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDV4033671.1"
                     /translation="MLNGGGILFKANHVPVLMYHHVSHCPGLVTLSPETFRKQMKWLA
                     ENNWKTLSSDELEFFYRGGKLPRKSVMLTFDDGYLDNWFQVYPLLNEFNLKAHIFLIT
                     SFIGNGPVRHSPGKEYSHRDCEHQIATGNADNVMLRWSEVNEMLQSGLVEFHVHTHTH
                     TRWDKKFTSREEQCKHLRQDLLSGREYLKKMTGKCSKHLCWPEGYYNKDYIQIAEELG
                     FHYLYTTERRMNAPTKGTTRIGRISTKERENCVWLKRRLFYYTTPFFSSLLALHKGPR
                     "
BASE COUNT          286 a          159 c          186 g          266 t
ORIGIN      
        1 tatataaagt tcaccaactt tattaggctt tccttttatc tctacttact gggtgccaga
       61 aactttaaat tttaaacgga gggggcattt tgtttaaagc aaatcatgtt ccggtattaa
      121 tgtatcatca tgtcagccat tgcccaggac tggttacact ttctcccgag acattccgga
      181 aacaaatgaa atggttggct gaaaacaact ggaaaacact gtcatcagat gaactggagt
      241 ttttttatcg gggcggaaaa cttccccgta aaagcgttat gttgacattt gatgatggat
      301 accttgacaa ctggtttcag gtatatcctt tattaaacga gtttaatctc aaggcacata
      361 tttttttaat taccagtttt attggaaatg gtccggttcg tcactctcct ggaaaggaat
      421 attctcatcg cgattgcgaa catcaaatag caaccgggaa tgctgataat gttatgcttc
      481 gctggtctga agtgaacgaa atgttgcaat ctggtctggt cgaatttcat gttcatacac
      541 atactcatac acgttgggat aaaaagttca cttcacgaga agaacagtgt aaacatcttc
      601 ggcaggactt attgagcggg agagaatatt taaaaaaaat gacaggaaaa tgcagtaaac
      661 atttgtgttg gccggaaggt tattataaca aggattatat tcagatcgct gaagaacttg
      721 gattccatta tttatataca acagaaagaa gaatgaatgc tccaactaaa ggaactacac
      781 ggataggaag aataagcacc aaggaacggg aaaattgcgt atggctgaaa agacgacttt
      841 tttattatac aacaccgttt ttttcatcgt tgctggccct tcataagggg ccaagat
//
LOCUS       DAPHKZ010000309          888 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.314, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000309 DAPHKZ010000000
VERSION     DAPHKZ010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..888
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.314"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..715
                     /gene="ydeO"
                     /locus_tag="RH288_004729"
     CDS             <1..715
                     /gene="ydeO"
                     /locus_tag="RH288_004729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acid stress response transcriptional regulator
                     YdeO"
                     /protein_id="HDV4033672.1"
                     /translation="NILDKDYAFSDGEILMVDNAVRTHFEPYKRHFKEIGFNENTIKK
                     YLQCTNIQTVTMPVPAKFLRASNVPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIF
                     AACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCLYISESLLKKKLKQEQT
                     TFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYAFRKHFGNSPKRVSKEY
                     RCQRHTGMNTGNTMSALAI"
BASE COUNT          276 a          173 c          171 g          268 t
ORIGIN      
        1 taacatttta gataaagatt acgccttctc tgacggcgag atcctgatgg tagataacgc
       61 tgttcgtaca cattttgaac cttataagcg gcattttaaa gaaatcggat ttaatgaaaa
      121 taccattaaa aaatatctac aatgcactaa catccagaca gtgacgatgc ctgttcctgc
      181 gaagttttta cgtgcttcaa atgtaccgac tggattgctt aatgaaatga ttgcttatct
      241 caactcggaa gaacgcaatc atcataattt ttcagaactt ttgctttttt cttgcctgtc
      301 tatttttgcc gcatgcaaag gtttcattac actattaact aacggtgtgc tatccgtttc
      361 cgggaaagtg agaaatattg tcaacatgaa gctggcgcac ccatggaagc tgaaagatat
      421 ttgtgactgc ctgtacatca gtgaaagcct gttgaagaaa aaacttaagc aagagcaaac
      481 gacattctca cagattcttt tagatgccag aatgcagcat gcaaaaaatt tgatacgcgt
      541 agaaggttca gtcaataaaa ttgccgaaca atgtggttat gccagtacat cttattttat
      601 ttatgcgttc cgcaaacatt tcggcaacag tccgaagaga gtttctaagg agtaccgttg
      661 tcaaaggcac acgggtatga atacgggcaa cacgatgagt gctttagcta tttgattatt
      721 tgctaacgag tagtcaacca cgcacgctac gtaaaaatta aaatggggca gccattccct
      781 gccccgcgtt gtttttaggc gatatattta ttgaaataaa taagtgacat ccatcacata
      841 tttatgcact tgcataacct gttgcatgat tatttatgat ctcaattc
//
LOCUS       DAPHKZ010000310          858 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.315, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000310 DAPHKZ010000000
VERSION     DAPHKZ010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.315"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..585
                     /gene="rfaY"
                     /locus_tag="RH288_004730"
     CDS             <1..585
                     /gene="rfaY"
                     /locus_tag="RH288_004730"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II) kinase RfaY"
                     /protein_id="HDV4033673.1"
                     /translation="FRSIDDTKVMLIDTDYGKLILKVFSPKVKRNERFFKSLLKGDYY
                     ERLFEQTQKVRNEGLNTLNDFYLLAERKTLRFVHTYIMIIEYIDGIELCDMPDIDDAL
                     KNKIQQSINALHQHGMVSGDPHRGNFIIKNGEVRIIDLSGKRASAQRKAKDRIDLERH
                     YGIKNEIRDLGYYLLVYRKKMRNFMRRLKGKPAR"
     gene            656..>858
                     /locus_tag="RH288_004731"
     CDS             656..>858
                     /locus_tag="RH288_004731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-oct-2-ulosonate III transferase
                     WaaZ"
                     /protein_id="HDV4033674.1"
                     /translation="MKNIRYIDKKDVENLIENKTSDDVIIFLSGPTSQKTPLSVLRTK
                     DIIAVNGSAQYLLSNNIVPFIYVL"
BASE COUNT          281 a          141 c          158 g          278 t
ORIGIN      
        1 tttcgttcta ttgatgatac aaaagttatg cttattgata ccgattacgg taaattgatt
       61 cttaaggttt tttctccgaa agttaagcgt aacgaacgtt tctttaagtc tctgttaaaa
      121 ggtgattatt acgaacgcct ttttgagcaa acccaaaaag tacgaaatga agggttaaat
      181 acactcaatg acttttattt attggctgaa cggaaaacct tacgttttgt ccatacttat
      241 atcatgatca tcgagtatat tgatggcata gagttgtgtg atatgcccga tattgatgat
      301 gcgctaaaaa ataaaattca gcaatcaatt aatgccttac atcaacatgg catggtttct
      361 ggcgaccccc atcgtggtaa cttcattata aaaaatggtg aggttcgaat tatcgatctc
      421 tccggaaagc gtgcttcagc gcagcgtaaa gcgaaagatc gtattgactt agagcgtcat
      481 tacggtatta aaaatgagat tagagatcta ggctattatc ttttagtata tcgtaaaaaa
      541 atgcgcaatt ttatgcggcg tttgaaaggg aaaccagcgc gctaaaaaaa atcccacaat
      601 tacatgtctt caccaggaca gttttaagcg gagttattta tttcacaggt ttatcatgaa
      661 gaatattaga tacattgaca aaaaagatgt tgaaaacctg attgaaaata aaacatctga
      721 tgatgttatt atttttcttt cgggccctac atcgcaaaaa acacctttgt cagtattacg
      781 aacaaaggat attattgctg tcaatggttc tgcgcaatat ctgttaagta ataatatcgt
      841 tccttttata tatgtact
//
LOCUS       DAPHKZ010000311          831 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.316, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000311 DAPHKZ010000000
VERSION     DAPHKZ010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..831
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.316"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..831
                     /locus_tag="RH288_004732"
                     /pseudo
     CDS             1..831
                     /locus_tag="RH288_004732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT          276 a          143 c          187 g          225 t
ORIGIN      
        1 ttaaaaaatt gatggaacat atttctatta ttcccgatta cagataagcc tggaaagtag
       61 agcataaatt gtcaggcatc ctactattga ctatttttgc cgttatttct ggtgcagaaa
      121 gttgggaaga tatagaggat ttcggggaaa cacatctcga tttcttgaag caatatggtg
      181 attttgaaaa tggtattcct gttcacgata ctattgccag agttgtatcc tgtatcagtc
      241 ctgcaaaatt tcacgagtgc tttattaact ggatgcgtga ttgccattca tcaaatgata
      301 aagacgtcat tgcaattgat ggaaaaacgc tccggcactc ttatgacaag agtcgccgca
      361 ggggagcgat tcatgtcatt agtgcgttct caacaatgca cagtctggtc atcgggcaga
      421 tcaagacgga taagaaatcc aatgagatca cagctatccc tgaacttctt aacatgctgg
      481 atattaaagg aaaaatcatc acaactgatg cgatgggttg ccagaaagat attgcagaga
      541 agatacaaaa acagggaggt gattatttat tcgctgtaaa aggaaaccag gggcggctta
      601 ataaagcctt tgaggaaaaa tttccgctga aagaattaaa taatccagag catgacagtt
      661 acgcaatgag tgaaaagagt cacggcagag aagaaatccg tcttcatatt gtttgcgatg
      721 tccctgatga acttattgat ttcacgtttg aatggaaagg actgaagaaa ttatgcgtgg
      781 cagtctcctt tcggtcaata atagcagaac aaaagaaaga gccagaaatg a
//
LOCUS       DAPHKZ010000312          831 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.317, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000312 DAPHKZ010000000
VERSION     DAPHKZ010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..831
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.317"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            714..815
                     /locus_tag="RH288_004733"
     CDS             714..815
                     /locus_tag="RH288_004733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033675.1"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
BASE COUNT          264 a          181 c          145 g          241 t
ORIGIN      
        1 ttcatcggac tgtaaattgc ggagatatcg aacttgcact acccatcgca acactcaaac
       61 agatttatga atttcgttca taacccctga caaattctgc cgtctaatcg agcttttccc
      121 tttacgttat gcttctcatg aacgataaca caacttgttc atgaattaac cattccggat
      181 aaactatggg atcaaattca ggcatcgaaa ggaactggct ggtttccgtt aatggattaa
      241 atatctatta ttctcccgag agtaaaacta tcaaatcaat gagtaaccga tacagcctca
      301 caaattcttt cagataatta ccccgtcact gcggcacgtt ctctcataag gcgtgcctgc
      361 agtgtaatcc agtatgtatc cggcatagtt gacggtttaa tagaactcaa ttcctctccc
      421 aggtcaccaa caacgatatc ttgtataaca ccccaggaga tacgacatta tgatgagatg
      481 cgatatgctc ctcagcacca atcaacgccc ggactgggcc agtcttgaga tcagactcat
      541 tcccggaact gacttcaggc gacatatatc aatgacgttg gtgcaataaa agatagttga
      601 tgtaatacat ctattcaaat ttgtgataca tgtcaaaaaa ttggttgacc aaactcgtta
      661 tttatataag ggcacttacg aagtgcactc ttttttaaag cgaggaagta ccaatgaaag
      721 agaataaagt acagcaaatc agtcataaac tgattaatat cgttgttttt gtcgcaattg
      781 tagaatacgc ctatttattt ctccatttct attaataacg gaaataaact g
//
LOCUS       DAPHKZ010000313          819 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.318, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000313 DAPHKZ010000000
VERSION     DAPHKZ010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..819
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.318"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..488)
                     /locus_tag="RH288_004734"
     CDS             complement(<1..488)
                     /locus_tag="RH288_004734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417590.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033676.1"
                     /translation="MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTN
                     DVNKIYSISNELRRVLSAITALNFYHGDVPSVMIRIQPENMSPFIIDISTGEHDDYII
                     QTLDVGTFAPFGEQCTCSAVNKKELECIKETISKYCAKFTRKEAILTPLVHFNKTSIT
                     SD"
     gene            complement(744..>819)
                     /locus_tag="RH288_004735"
     CDS             complement(744..>819)
                     /locus_tag="RH288_004735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417589.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TdcR"
                     /protein_id="HDV4033677.1"
                     /translation="LEQLINVNFFSSDRTSFCECNRFP"
BASE COUNT          240 a          157 c          160 g          262 t
ORIGIN      
        1 caatctgaag taatgctggt tttattaaag tgcacaaggg gggttaagat ggcttctttt
       61 cgggtgaatt ttgcacaata cttagaaatc gtctccttaa tacattccag ctctttttta
      121 ttgacggctg agcaagtaca ttgttcacca aaaggtgcaa aagtgcctac atctaatgtt
      181 tgtatgatat aatcatcatg ttctcctgta gaaatatcta taatgaatgg actcatattt
      241 tccggttgga ttcggatcat gacagaagga acatcgccat gatagaaatt caatgcagtt
      301 attgcagata atactctccg cagttcatta cttatactgt aaattttatt aacgtcattg
      361 gtggagacaa tttctgcaaa ctttcttttt accgtccaat aatcaatatt tctattgtga
      421 ttgttaacca ctgcgtgcat tggcgggatt gaagggtgaa aaatatgcgc aattgggaag
      481 cctttcattg atgcctgcct tgtcatcatg acaaacaata atagatgctt attttcctcg
      541 cagggttctt tcgcactatc aaaaaacgct catttacccg gcgttacagt aaacgaagca
      601 acatcctgtg gcctacgccg atcaaaagct ctgtgaaaat ttcccttgtt gtctttgtct
      661 gaccttatcg cggcgatcag caattattcg ttttgtgatc ctcaacacaa aatgctattc
      721 gtcgcctatg aggggagaag aatttatgga aaacgattgc attcacaaaa tgacgtcctg
      781 tcagaagaga aaaagttgac gttaatcaat tgttcgaga
//
LOCUS       DAPHKZ010000314          815 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.319, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000314 DAPHKZ010000000
VERSION     DAPHKZ010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..815
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.319"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..331)
                     /locus_tag="RH288_004736"
     CDS             complement(<1..331)
                     /locus_tag="RH288_004736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033678.1"
                     /translation="MNVYLIRHDVDNFKFYLQDESDFFSVAAFDFCGESLFNGWKPYK
                     IELFKGKTKAERSLKGDFNSSCFSSGLLYVEHSLADVLSRQVNNIELLKVITSDDRDF
                     YYANVVGK"
     gene            complement(345..710)
                     /locus_tag="RH288_004737"
     CDS             complement(345..710)
                     /locus_tag="RH288_004737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AHH domain-containing protein"
                     /protein_id="HDV4033679.1"
                     /translation="MKRANRNLAKSAGYMNRAWYKFKGSAAHHIVAWDDPRALGARKI
                     LEKYGIHIDSAENGIFLKHVDPNSLQPGSYHRVIHTNKYYADVEARLADAAKANGKQG
                     VLDELDAIRDDLLFNRLIY"
BASE COUNT          247 a          189 c          133 g          246 t
ORIGIN      
        1 tttttcctac cacgtttgca taataaaaat cacgatcatc actggtgatt acttttaaca
       61 actcaatatt atttacctga cgagataata catctgcgag agaatgttcg acgtataata
      121 atcctgagct aaaacatgat gaattaaaat cgccttttaa tgatctctca gctttagttt
      181 ttcctttaaa tagctctatt ttgtatggtt tccatccatt aaatagagac tctccacaaa
      241 aatcaaaagc agcaactgaa aaaaaatcac tctcgtcttg caagtaaaac ttgaagttgt
      301 ccacatcatg ccgaattaaa taaacattca ttactatgcc cttattaata aattagtcta
      361 ttaaaaagca ggtcatccct gatagcatct aactcatcaa gaacaccttg tttcccatta
      421 gccttagctg cgtctgcgag tcgtgcctca acatcagcat aatatttgtt cgtatgaata
      481 acacgatgat aagaccctgg ctgaagagag tttggatcta catgtttcaa aaatattcca
      541 ttttctgcgg aatcaatgtg tataccatat ttttccagaa tttttcttgc gcctaaagca
      601 cgggggtcat cccaggcaac aatatgatgg gcggcagaac ctttgaattt ataccaagct
      661 cgattcatgt atccggcact cttagctagg tttctgttag cccgtttcat tgcccttgcc
      721 agagctctgg ggcaaccagc aagtccatac tggtcaatcc aacccagagg attaggcaca
      781 taccggtaag tctgctcccc tccctgcaac cccag
//
LOCUS       DAPHKZ010000315          809 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.320, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000315 DAPHKZ010000000
VERSION     DAPHKZ010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.320"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>809
                     /locus_tag="RH288_004738"
     CDS             <1..>809
                     /locus_tag="RH288_004738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033680.1"
                     /translation="SAECRIIVIANPKPDKAIITKISVEEGIPITFSVQTMFSDTNFI
                     AEQRADLPTNIKDIQSLYQKMTKLYIEHSENKNRMKVFAGTNFIDFNMTGQNLSGFVL
                     TLSRFYFEDLLNINFTDANLGDTIFLHKEHPTPKLYKDGQYLDKQIEGLFSTLLTIND
                     NLLRAKAEIASTIIKFLEARITNLSYNDILKYQQEFQKQCYKQVKAFTTLSRYNKIQT
                     WAEMSEYQFEVFQYETLNPKKMSHTPYLKRPLPNEKDINYGVEIEIPSGKR"
BASE COUNT          318 a          148 c          122 g          221 t
ORIGIN      
        1 aagtgctgaa tgtcgaatca ttgttatcgc taatcctaaa cccgacaagg caatcataac
       61 taaaattagc gtagaagagg gaatacccat aacattcagt gtccaaacca tgttttcaga
      121 tactaatttt attgctgaac aacgagctga cttaccaact aatataaaag atattcaaag
      181 cctgtatcaa aaaatgacga agttatatat tgagcacagt gaaaataaaa acaggatgaa
      241 agtctttgcc ggaaccaact ttattgattt caatatgaca ggacagaacc tgtccgggtt
      301 cgttctaacc ttgtcaaggt tttatttcga agatctactt aatataaatt tcactgacgc
      361 aaatttaggt gacactattt ttttacataa agaacaccct acccccaaat tatataaaga
      421 tggacaatat cttgacaaac aaatcgaagg tttattttca acattattaa ccattaatga
      481 caacctttta cgagcaaaag cggaaattgc ttcgacaata attaaatttt tagaggccag
      541 gataaccaat ctttcataca atgacatatt aaaatatcag caagaattcc aaaaacaatg
      601 ttataagcaa gttaaagcct ttacgacact ctcccgatac aataaaattc aaacatgggc
      661 agaaatgtct gaatatcaat tcgaagtatt tcaatacgag acgcttaacc caaaaaaaat
      721 gtcacacacg ccttatttaa agaggccact gcctaatgaa aaagatataa attatggggt
      781 ggaaatagaa ataccatctg gtaaaagaa
//
LOCUS       DAPHKZ010000316          796 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.321, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000316 DAPHKZ010000000
VERSION     DAPHKZ010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.321"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            57..>796
                     /locus_tag="RH288_004739"
     CDS             57..>796
                     /locus_tag="RH288_004739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033681.1"
                     /translation="MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTP
                     QQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLNSPVILVQSGNRAPETIMQEEMR
                     KYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVASAENMNWMQALRFVAAKGHQKAIIV
                     YQDMLQTGKYDSALKSTVWSDYKNDKLTDAISLRYLVRFTLVDVATGEWATWSPVNYE
                     YKVLPPLPDKNEASTTDMTEQQIMQLKQ"
BASE COUNT          255 a          166 c          175 g          200 t
ORIGIN      
        1 tccgttatca atgctaaata ttctaatcat tatgacaggc gagggagtgt ccaattatga
       61 attcaaaaaa gctttgttgc atatgtgtgt tattctcgct gcttgcagga tgtgcctctg
      121 aatcttctat tgatgaaaag aagaaaaaag ctcaagtcac acaaagtaat attaataaaa
      181 acactcccca gcaactgaca gacaaagatt tattcggtaa tgaaaccact ctggccgtat
      241 ccgaagagga tattcaagct gcgcttgatg gagatgagtt ccgcgttccc cttaattctc
      301 ctgtaatact tgttcaatcc ggcaaccgcg caccggaaac cattatgcag gaggagatgc
      361 gaaaatatta tactgtttcc acattctctg gtatcccgga caggcaaaag cctctgactt
      421 gtaacaaaaa caaagataaa aatgagaacg aggatgttgc cagtgctgag aatatgaact
      481 ggatgcaggc actgcgtttt gtggctgcaa aaggacatca gaaagcgatt attgtttacc
      541 aggatatgtt gcagacagga aaatatgact ctgcgctgaa atcaacagta tggtccgact
      601 ataaaaatga caaactcact gacgctatct ccctgcgcta cctggtacgt ttcacgctgg
      661 tggatgtggc aacaggtgag tgggctacct ggtcgccggt gaattatgaa tataaagtgc
      721 ttccaccatt gcccgacaag aatgaagcca gtacgactga tatgacagag cagcaaatca
      781 tgcaacttaa gcaaaa
//
LOCUS       DAPHKZ010000317          789 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.322, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000317 DAPHKZ010000000
VERSION     DAPHKZ010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.322"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>789
                     /locus_tag="RH288_004740"
     CDS             <1..>789
                     /locus_tag="RH288_004740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV4033682.1"
                     /translation="ISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYATDPAGNRLP
                     DPELHPDSTLTVWPDNRIAEDAHYVYRHDEYGRLTEKTDRIPAGVIRTDDERTHHYHY
                     DSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDLTGWMSLSRKPEVTWY
                     GWDGDRLTTVQTDTTRIQTVYEPGSFTPLIRVETENGEREKAQRRSLAETLQQEGSEN
                     GHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLA"
BASE COUNT          173 a          234 c          284 g           98 t
ORIGIN      
        1 atcagcggcc cgcgacagac gcgggaatac ggctacagcg ccacgggcag gctggagagt
       61 gtgcgcaccc tcgcaccaga cctggacatc cgcatcccgt atgccacgga cccggcgggc
      121 aaccggctgc cggacccgga gctgcacccg gacagtacac tcacagtgtg gccggataac
      181 cgcatcgcgg aggatgcgca ctatgtctac cgccacgatg aatacggcag gctgacggag
      241 aagacggacc gcatcccggc gggtgtgata cggacggacg acgagcggac ccaccactac
      301 cactacgaca gccagcaccg cctggtgttc tacacgcgga tacagcatgg cgagccactg
      361 gtcgagagcc gctacctcta cgacccgctg ggacggcgaa tggcaaaacg ggtctggcgg
      421 cgggagcgtg acctgacggg gtggatgtcg ctgtcgcgta aaccggaggt gacgtggtat
      481 ggctgggacg gagacaggct gacgacggtg cagactgaca ccacacgtat ccagacggta
      541 tacgagccgg gaagcttcac gccgctcatc cgggtcgaga cagagaacgg cgagcgggaa
      601 aaagcgcagc ggcgcagcct ggcagagacg ctccagcagg aagggagtga gaacggccac
      661 ggcgtggtgt tcccggctga actggtgcgg ctgctggaca ggctggagga agaaatccgg
      721 gcagaccgcg tgagcagtga aagccgggcg tggcttgcgc agtgcgggct gacggtggag
      781 caactggcc
//
LOCUS       DAPHKZ010000318          759 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.323, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000318 DAPHKZ010000000
VERSION     DAPHKZ010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.323"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
BASE COUNT          221 a          157 c          159 g          222 t
ORIGIN      
        1 tagcaaaaaa aaataacacc catcattatt aatgtttgta aagagcccac gttttcagtg
       61 ggctgattag tccaaaagct gaagttcttg gtgctgaata aatcctgaat gaattttcct
      121 tgtagtggtc aataaaaacc gaactccatt ttatttttta tttctctgca cacctcagtc
      181 agtttgatca gctgctgaaa aaactcagcg ttgaagccgc tttcaatgca gaaatggcac
      241 accatctcgg gtatgaaaaa aatcagcccc gtattaccgg gacggataac tgcaagtatc
      301 ccgcataatc gtgccattca tatttagaaa tcatccggca taatcaatct gccaacgaag
      361 gagatcgcta tgcgtacagc ccgttttact gagcatcaga tcatcgctgt gattaagtcg
      421 attgaagccg gacgaattgt taaagatgtt tgctgacctg agcctggaga accgagtgct
      481 gaaggatgtt atcgaaaaag ctttaaaaca agcctgtaag cgtgagttgg ttactcatct
      541 gataacgaca ttcgggctca gcatccgtca ggcctgccag agtttgaacc tgagcagaac
      601 ggcttaccat taccgcccag ataccacgcg tgatgaaccc gttataaacg gggctattta
      661 tatgcttacc ttttgtgtat taccctcaat attaaattaa tgttgagggt atttgggtgc
      721 gatattgttt ttttgaggcg taattttaca gtattattt
//
LOCUS       DAPHKZ010000319          758 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.324, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000319 DAPHKZ010000000
VERSION     DAPHKZ010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.324"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
BASE COUNT          185 a          155 c          168 g          250 t
ORIGIN      
        1 atttcataga aaaatattaa tgacgtcctg tggcgtatgc atgatgcaag gttgaacgca
       61 tgtaatatga tatttatcac gtaaatgcag tgtaatcttc ttgcattgtt tttaggttgc
      121 tattccgttt atctgaggac tgctggctat tgttgtgcag ttttcctgat acagctttat
      181 gcaggttttc cagcattaca gtaaaacccg ggaacatcag tgctgctcgt ttctttctcc
      241 tgtatccact cccgcttatg gatacttcct taaatattct ctcgtctgac taaagcatat
      301 atacccgctc atgggatgtt ggctgtaatg attttcctga gcggattatt actgatgacc
      361 ataagtatgt ctcagcacag tcatcgtaac gtgctggtta acctggccat ggtagccaaa
      421 tcatcatcct gtatattctg ttgagggagg cactggtgat tgttcagaat acggctgatg
      481 cgaaaaagtg taggctgttt cctttattgg tgtgatgtac agcctcttta cgctctactc
      541 ttccggggaa gaagccatgc tgtagcactt tattgttact tttcctggct ggacactgta
      601 tggtctggta tccccccacg ttttgaacgg aaaaaacaga tttaaagttg ccagtagtct
      661 gtaagtttct gcatcccatt tccccacaga cagtattctc ctgcaatgtg atgaatggtt
      721 tcctggaaca ggaaaggaac taagtcagat agtgggga
//
LOCUS       DAPHKZ010000320          758 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.325, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000320 DAPHKZ010000000
VERSION     DAPHKZ010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.325"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..>758)
                     /gene="rfaJ"
                     /locus_tag="RH288_004741"
     CDS             complement(<1..>758)
                     /gene="rfaJ"
                     /locus_tag="RH288_004741"
                     /EC_number="2.4.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide 1,2-glucosyltransferase RfaJ"
                     /protein_id="HDV4033683.1"
                     /translation="PAIEIDKVKAWDFRLANINTSECLNVAYGVDANYLDGVGVSITS
                     IVLNNRHINLDFYIIADVYNDGFFQKIAKLAEQNQLRITLYRINTDKLQCLPCTQVWS
                     RAMYFRLFAFQLLGLTLDRLLYLDADVVCKGDISQLLHLGLNGAVAAVVKDVEPMQEK
                     AVSRLSDPELLGQYFNSGVVYLDLKKWADAKLTEKALSILMSKDNVYKYPDQDVMNVL
                     LKGMTLFLPREYNTIYTIKSELKDKTHQNYKKLI"
BASE COUNT          259 a          146 c          112 g          241 t
ORIGIN      
        1 taatcagctt tttatagttt tgatgtgttt tgtcttttaa ttcactttta attgtataaa
       61 ttgtattgta ctcacgaggc aaaaataatg tcatcccttt cagtaagaca ttcataacat
      121 cctgatcagg gtatttataa acattatctt tactcataag aatagacaac gctttttctg
      181 ttagttttgc gtcagcccat ttttttaagt ctaaataaac gacaccggaa ttaaagtact
      241 gcccaagtaa ttcaggatca gacaacctgg ataccgcctt ttcttgcatt ggctcaacat
      301 ctttaacaac agcagcaacc gctccattta aacccagatg taatagttgg ctaatatcgc
      361 ctttacaaac aacatctgca tcaagataaa gcaaacgatc aagcgttaaa cccaataatt
      421 gaaatgcaaa taaacggaag tacattgctc ttgaccagac ctgtgtacaa ggcaagcact
      481 ggagcttatc agtgttaatt ctatataacg tgattcttaa ttggttttgc tctgcaagct
      541 ttgcaatttt ttgaaaaaaa ccatcattat aaacatcagc aataatataa aaatcaagat
      601 taatatgtcg attatttagg acaattgatg tgatggaaac acctacacca tcaagataat
      661 tagcatcgac accataggca acatttaaac attcagaagt atttatatta gctagccgaa
      721 aatcccaggc tttaacttta tctatctcta tggcagga
//
LOCUS       DAPHKZ010000321          757 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.326, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000321 DAPHKZ010000000
VERSION     DAPHKZ010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.326"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..267
                     /locus_tag="RH288_004742"
     CDS             <1..267
                     /locus_tag="RH288_004742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HDV4033684.1"
                     /translation="VVTGLLAANVAHAAEVYNKDGNKLDLYGKVTALRYFTDDKRDDG
                     DKTYARLGFKGETQINDQMIGFGHWEYDFKGYNDEANGSRGKNL"
     gene            291..>757
                     /locus_tag="RH288_004743"
     CDS             291..>757
                     /locus_tag="RH288_004743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HDV4033685.1"
                     /translation="MITDLILHNHPRMKTITLNDNHIAHLNAKNTTKLEYLNLSNNNL
                     LPTNDIDQLISSKHLWHVLVNGINNDPLAQMQYWTAVRNIIDDTNEVTIDLSGLNLTT
                     QPPGLQNFTSINLDNNQLTHFDATNYDRLVKLSLNSNALESINFPQGRNVSIT"
BASE COUNT          269 a          156 c          128 g          204 t
ORIGIN      
        1 gttgtaactg gtttgttagc tgcgaacgta gcacacgctg ccgaagtcta taacaaggat
       61 ggtaataaac tcgaccttta tggcaaggtt accgctctac gttattttac tgatgataag
      121 cgtgacgatg gtgataaaac ttatgcccgt ctcggcttta aaggagaaac gcaaatcaat
      181 gatcaaatga ttggttttgg tcactgggaa tatgatttta aaggctataa cgatgaagcc
      241 aacggctcgc gcggcaagaa tctctgattg agttaagtgc ccatcacaat atgatcactg
      301 accttatatt acacaatcat cccaggatga aaacaatcac tttaaacgac aaccatattg
      361 cacatttaaa cgccaaaaac actacaaaac tggaatattt aaacttaagc aataacaatt
      421 tactgccaac caatgacatt gatcaactaa tatcatcaaa acatctttgg catgtattag
      481 ttaacggcat caacaatgat ccacttgcac aaatgcagta ctggactgca gtaagaaata
      541 taattgatga cactaatgaa gtgaccattg atttatcagg acttaattta accactcaac
      601 caccagggct gcaaaacttc acatctatca atcttgataa taaccaactc acacattttg
      661 atgcaaccaa ctacgataga ctcgtaaagc taagtctgaa tagtaatgct cttgagtcaa
      721 taaattttcc tcaaggcaga aatgtaagta ttacaca
//
LOCUS       DAPHKZ010000322          751 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.327, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000322 DAPHKZ010000000
VERSION     DAPHKZ010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.327"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>751
                     /locus_tag="RH288_004744"
     CDS             <1..>751
                     /locus_tag="RH288_004744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HDV4033686.1"
                     /translation="IVYLTVTGEQQGSISAGCGTSESTGNRWQSGHEDEIFTFSLLNN
                     INNTGLGSQFHGITFCKLIDKSTPLFINSINNNEQLFMGFDFYRINRFGRLEKYYYIQ
                     LRGAFLSAIHHQIIENQLDTETITISYEFILCQHLIANTEFSYLALPENYNRLFLPNS
                     KNQTNNRFKTLNSKAIGRLLAAGGVYNGNIEGFRDTAEKLGGDAIKGYDQILNEKTAG
                     IAIATASILLTKRSNVDTYTEINSYLGKLRGQ"
BASE COUNT          269 a          124 c          137 g          221 t
ORIGIN      
        1 tattgtttac ctgacagtaa cgggagaaca acaaggaagc atctccgcag gttgtgggac
       61 ttctgagtct acaggtaatc gttggcagag cgggcatgag gatgaaatat ttacattctc
      121 actcttaaat aatattaata atacggggct tggttcacag ttccatggta taacattttg
      181 taaattaatt gataaaagca ctccattatt tattaattcc attaacaata atgaacaatt
      241 atttatggga tttgacttct atcgaataaa tagatttggt agattggaaa agtattatta
      301 tatacaacta agaggcgctt ttttatcggc tattcatcac cagatcattg aaaaccaact
      361 ggatacagaa acaataacta ttagttatga atttatcctc tgtcaacatc ttatcgcaaa
      421 taccgagttc agctatttgg cactccctga aaattataac cgtttgtttt taccaaattc
      481 aaaaaaccaa acaaataatc gtttcaaaac gttaaacagc aaagctattg gcaggctact
      541 tgctgctggt ggcgtataca atgggaacat tgaaggattc agagatactg cggaaaaact
      601 gggtggagat gcaataaaag gctatgatca aatactaaat gaaaaaacag cgggcatagc
      661 gatagcaaca gcatctattc ttttaacaaa gcgttctaat gttgatacat atacagaaat
      721 aaatagttac ttaggcaaac ttagaggtca a
//
LOCUS       DAPHKZ010000323          746 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.328, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000323 DAPHKZ010000000
VERSION     DAPHKZ010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.328"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>746
                     /locus_tag="RH288_004745"
     CDS             <1..>746
                     /locus_tag="RH288_004745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide 1,3-galactosyltransferase"
                     /protein_id="HDV4033687.1"
                     /translation="FTDYFGDDDRKYFDALALQYKTRIKIYLINGDRLRSLPSTKNWT
                     HAIYFRFVIADYFINKAPKVLYLDADIICQGTIEPLINFSFPDDKVAMVVTEGQADWW
                     EKRAHSLGVAGIAKGYFNSGFLLINTAQWAAQQVSARAIAMLNEPEIIKKITHPDQDV
                     LNMLLADKLIFADIKYNTQFSLNYQLKESFINPVTNDTIFIHYIGPTKPWHDWAWDYP
                     VSQAFMEAKNASPWKNTALLKPNNSNQLRY"
BASE COUNT          229 a          137 c          150 g          230 t
ORIGIN      
        1 ttttactgat tattttggtg atgatgatcg taagtatttt gatgccctgg cgttgcagta
       61 taaaaccaga attaaaatat atctgattaa tggtgatcga ctgcgctcat tgcctagcac
      121 taagaattgg actcatgcaa tatattttcg ttttgttatt gcagattact ttattaataa
      181 ggcgcctaaa gtcctttatc tggatgcaga tatcatttgt caggggacta ttgagccact
      241 aattaatttc tcatttcctg acgataaagt cgcaatggtt gttacagaag ggcaagctga
      301 ctggtgggaa aaacgcgccc attcgttagg tgttgcggga attgctaaag gttactttaa
      361 ctccggtttt ttattgatta atactgccca atgggcggct cagcaggttt ctgcacgagc
      421 tattgcaatg ctaaatgagc cagaaataat caaaaaaata acacatcctg atcaggatgt
      481 gttaaatatg ttgctggcgg ataaacttat tttcgctgat attaaatata acacccagtt
      541 cagcttaaat tatcaactca aagaaagctt tataaaccca gtaaccaacg atactatttt
      601 tatccattat atcgggccaa ccaagccctg gcatgattgg gcctgggatt atcctgtatc
      661 acaagccttt atggaggcaa aaaatgcttc gccatggaag aatacggcgt tgctgaaacc
      721 gaacaatagc aatcaattaa gatata
//
LOCUS       DAPHKZ010000324          744 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.329, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000324 DAPHKZ010000000
VERSION     DAPHKZ010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.329"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
BASE COUNT          212 a          146 c          156 g          230 t
ORIGIN      
        1 aattatacga acttgaatat tgcactgata aacataatga acttggcata aaaagagtaa
       61 gtaaaccaga aaagggatat cagccacatg ttcttcaata tatgattggc aactgtacaa
      121 tatatttcgt tccggactgt caggataatt actcattact ggtacggaat tcatcttttg
      181 gccgtttacg tctgttccgt tatcctgatg atacgatgtt ctgcacgttc tgccgggaag
      241 atgcagatga tccgcttaaa agtattatga cccatctctg ggagctggat gcagagatga
      301 cagatcctgt catagctatg tttaatcacg tctgagtgcc gtgagtgatt tctgtctttt
      361 atgcaacagt gccaagatat tgtaatcaaa aaaaagcatt aatgcatttt ggacagtaat
      421 ctattttaat tgatgacata gaggcattaa tctttctttt tcttcaggaa gatccgaaaa
      481 ctcctggtca cggatcttcc tctcccgccg cacagcgcca tcttcccatc agcacaacat
      541 gtagttctga attcagctgc taatgacact atatgttgtg tcatctccct gacctgtgat
      601 gcgccgcgca ggggcggaaa acagtgatat gatgattttc tcagcgtggt acacttccgg
      661 aaagttgtga tattcatgaa agtcggatct gacagaaacg ggaatgcgat aattacggtt
      721 tgtttttata agtcagattt tgat
//
LOCUS       DAPHKZ010000325          733 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.330, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000325 DAPHKZ010000000
VERSION     DAPHKZ010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.330"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..560
                     /locus_tag="RH288_004746"
     CDS             <1..560
                     /locus_tag="RH288_004746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HDV4033688.1"
                     /translation="GQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNFYQYPL
                     NPVTNTDPLGLEVFPRPFPLPIPWPKSPAQQQADDNAAKALTKWWNDTASQRIFDSLI
                     LNNPGLALDITMIASRGNVADTGITDRVNDIINDRFWSDGKKPDRCDVLQELIDCGDI
                     SAKDAKSTQKAWNCRHSRQSNDKKR"
     gene            581..>733
                     /locus_tag="RH288_004747"
     CDS             581..>733
                     /locus_tag="RH288_004747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lyase"
                     /protein_id="HDV4033689.1"
                     /translation="MSNTYQKRKASKEYGLYNQCKKLNDDELFRLLDDHNSLKRISSA
                     RVLQLRG"
BASE COUNT          246 a          137 c          167 g          183 t
ORIGIN      
        1 cggggcagca gtatgatgag gagtccggcc tgtattacaa ccgccaccgc tattatgacc
       61 cgctgcaggg gcggtatatc actcaggatc cgattgggct gaagggggga tggaattttt
      121 atcagtatcc gttgaatcca gttacgaata cagatcctct ggggttagaa gtttttccta
      181 gaccattccc cttgccaatt ccatggccca aaagccctgc acagcagcaa gcagatgata
      241 atgctgcaaa agcattgaca aaatggtgga acgatacagc atcacaaaga atatttgact
      301 ctctaatatt gaataatccg ggactagcat tagatataac aatgatagct tctcgtggaa
      361 atgttgcaga cacagggata actgatcgtg tcaatgacat aataaatgac agattctgga
      421 gtgatgggaa aaaacccgac agatgtgacg tacttcagga actaattgat tgtggtgata
      481 ttagtgctaa agatgcaaaa agcacgcaga aagcctggaa ttgtcgtcac tccagacagt
      541 caaacgataa aaaaagatag cccttgtgga ggttcctgca atgtcaaata cataccagaa
      601 aagaaaggca agtaaagagt atggtttata taatcaatgt aagaaactaa atgatgatga
      661 attatttcgc ttacttgatg atcacaattc cttgaaaaga atttcatctg ccagagtatt
      721 acagttaaga ggt
//
LOCUS       DAPHKZ010000326          728 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.331, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000326 DAPHKZ010000000
VERSION     DAPHKZ010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.331"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            41..>728
                     /locus_tag="RH288_004748"
     CDS             41..>728
                     /locus_tag="RH288_004748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV4033690.1"
                     /translation="MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELN
                     TSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMIIAETLTSN
                     VNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGSDPDHIFEILLEAEVDVRD
                     VTEEEGNIVIYTEPTDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGL
                     VDALEDDDDVQ"
BASE COUNT          239 a          128 c          163 g          198 t
ORIGIN      
        1 ttaccagtaa tgtaaataaa ttttcgagga gatcattcca gtgggacgta aatgggccaa
       61 tattgttgct aaaaaaacgg ctaaagacgg tgcaacgtct aaaatttatg caaaattcgg
      121 tgtagaaatc tatgctgctg ctaaacaagg tgaacccgat ccagaattaa acacatcttt
      181 aaaattcgtt attgaacgtg caaagcaggc acaagttcca aagcacgtta ttgataaagc
      241 aattgataaa gccaaaggcg gcggagatga aacgttcgtg cagggccgtt atgaaggctt
      301 tggtcctaat ggctcaatga ttatcgccga gacattgact tcaaatgtta accgtacgat
      361 tgctaacgtt cgcacaattt tcaataaaaa aggcggcaat atcggagcgg caggttctgt
      421 cagctatatg tttgacaata cgggtgtgat tgtatttaaa ggatcagacc ctgaccatat
      481 ttttgaaatt ttacttgaag ctgaagttga tgttcgtgat gtgactgaag aagaaggtaa
      541 cattgttatt tataccgaac ctactgacct tcataaagga atcgcggctc taaaagcagc
      601 tggaatcact gagttctcaa caacagaatt agaaatgatt gcgcaatctg aagttgagct
      661 ttccccagaa gatttagaaa tctttgaagg gcttgttgat gcccttgaag atgacgacga
      721 tgtacaaa
//
LOCUS       DAPHKZ010000327          682 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.332, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000327 DAPHKZ010000000
VERSION     DAPHKZ010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..682
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.332"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..581)
                     /gene="fimE"
                     /locus_tag="RH288_004749"
     CDS             complement(<1..581)
                     /gene="fimE"
                     /locus_tag="RH288_004749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418733.1"
                     /note="upgraded from regulatory protein to switch DNA
                     invertase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimE"
                     /protein_id="HDV4033691.1"
                     /translation="MSKRRYLTGKEVQAMMQAVCYGATGARDYCLILLAYRHGMRISE
                     LLDLHYQDLDLNEGRINIRRLKNGFSTVHPLRFDEREAVERWTQERANWKGADRTDAI
                     FISRRGSRLSRQQAYRIIRDAGIEAGTVTQTHPHMLRHACGYELAERGADTRLIQDYL
                     GHRNIRHTVRYTASNAARFAGLWERNNLINEKL"
BASE COUNT          204 a          172 c          136 g          170 t
ORIGIN      
        1 tttaattttt cgtttatgag attatttctt tcccataatc cggcaaaacg agcagcatta
       61 ctggcggtat aacgcacagt atggcgaata tttcgatgcc cgagataatc ctgaattaaa
      121 cgagtatctg caccacgctc cgccaattca taaccgcaag catgccttaa catatgagga
      181 tgagtctgcg ttacggttcc agcttcaata ccggcatcgc gaataatgcg ataggcctgc
      241 tggcgagaaa gccgactccc gcggcgagaa ataaatatag cgtcagtccg gtcagcgcct
      301 ttccagttag cacgttcctg ggtccagcgt tccacggctt cacgctcatc aaaacgtaac
      361 gggtgaacgg tagaaaatcc gttcttcagt cggcgaatat ttattctacc ttcattaagg
      421 tcaaggtcct gataatgcag atcaagcagt tcactaatac gcatcccatg ccgatatgcc
      481 aacagaataa gacaataatc tctggctccc gttgccccgt aacaaaccgc ctgcatcatg
      541 gcctgaactt ctttaccggt aagataacga cgtttactca caatagtagt actcctaact
      601 gagatatatt tgaatgaata cctataggaa acctcaatcg gtcaaaatta gcccaataga
      661 taaaaagata accacacacg ga
//
LOCUS       DAPHKZ010000328          672 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.333, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000328 DAPHKZ010000000
VERSION     DAPHKZ010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.333"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>672
                     /locus_tag="RH288_004750"
     CDS             <1..>672
                     /locus_tag="RH288_004750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HDV4033692.1"
                     /translation="LTLCKHLRDLQFDIVLDPFETMPSFKHSLILSSLKDSYILGFDH
                     WYKRYYSFYHPHDECLKEHMSTRAIEILKHIYGEGKFSTNYDLHLPVDVEDKIKEFIG
                     DTRIVIINPLGAKKICRLTFEQIKVIYQEVKTHFENYRIIFTGLPQDLLTIPILEIET
                     LPFDEFIYTVALTKYSDFVISVDTALVHIAAAYHKPTLAFYPNSRTPEYPSHLIWSPN
                     HHKSI"
BASE COUNT          222 a          121 c          106 g          223 t
ORIGIN      
        1 gcttactcta tgtaagcatc tgcgggattt acagttcgat attgtattag acccctttga
       61 aactatgccc tcatttaagc atagcttaat attatcaagt ttaaaagatt cttacattct
      121 gggttttgat cattggtata agcgttacta ttcattttac catccccacg atgaatgttt
      181 aaaagaacat atgagtacac gagcaataga aatactgaag catatttatg gtgagggtaa
      241 attttccacc aactacgact tgcatttacc agtagatgtt gaagataaaa taaaagaatt
      301 tattggagat acaagaatag tcattattaa tccattaggt gcaaaaaaaa tatgccgtct
      361 tacgtttgag caaataaaag ttatatatca agaagtgaaa acacactttg aaaattatcg
      421 gattatattt accgggttac cgcaagattt attgacaata ccaatacttg aaatcgaaac
      481 actaccattt gatgagttta tttataccgt tgcgttgacc aagtatagtg attttgtcat
      541 ttctgttgat acagctcttg ttcatatcgc tgcggcttat cataaaccaa cgcttgcatt
      601 ttaccctaat tcacgtactc cggaatatcc ctcgcattta atttggtccc cgaatcatca
      661 taaatctata ca
//
LOCUS       DAPHKZ010000329          665 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.334, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000329 DAPHKZ010000000
VERSION     DAPHKZ010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..665
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.334"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            112..600
                     /gene="eco"
                     /locus_tag="RH288_004751"
     CDS             112..600
                     /gene="eco"
                     /locus_tag="RH288_004751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HDV4033693.1"
                     /translation="MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQV
                     IQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENKTLEGWGYDYYVFDKVSSPVS
                     TMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAV
                     VR"
BASE COUNT          201 a          146 c          170 g          148 t
ORIGIN      
        1 tctgaatgtt ctttaagtta ttcataaagc aaattaataa atctgatgaa tatgttaacc
       61 ttcagcgaca tcatcggtga aaacctataa atgaagaagg aaagcaaaaa aatgaagacc
      121 attctacctg cagtattgtt tgccgctttc gctaccactt ccgcctgggc ggcagaaagc
      181 gtccagccac tggaaaaaat cgcgccttat ccacaagctg aaaaagggat gaagcgtcag
      241 gtgattcagt taaccccgca agaagatgaa tctaccctga aagtagaact gttaatcggt
      301 cagacgctgg aagtcgattg caatttgcat cgtctcggcg ggaagctgga aaacaaaacg
      361 ctggaaggct ggggctatga ttattatgtc tttgataaag tcagttcccc ggtttcgacg
      421 atgatggcct gcccagatgg caagaaagag aagaaatttg tcaccgcgta tctgggcgat
      481 gctggaatgc tgcgttacaa cagcaagctg ccgatcgtgg tgtatacgcc agacaatgta
      541 gatgtgaagt accgcgtctg gaaggcggaa gagaaaattg acaacgcggt agttcgctaa
      601 actgccgtga agtgcggcac cccgtaggtc agacaaggcg gtcacgccgc atccgacatc
      661 caacg
//
LOCUS       DAPHKZ010000330          660 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.335, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000330 DAPHKZ010000000
VERSION     DAPHKZ010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..660
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.335"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            3..660
                     /locus_tag="RH288_004752"
                     /pseudo
     CDS             3..660
                     /locus_tag="RH288_004752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT          153 a          170 c          188 g          149 t
ORIGIN      
        1 ccgtggcttc catctccatc agttgtccct cctgctcagc tactgaaggc gtggtgcgta
       61 acggtaaaag tactgccgga catcagcgct atctctgctc tcactgccgt aaaacatggc
      121 agctacagtt cacttacacc gcctctcagc ccggtacaca ccagaaaatt attgatatgg
      181 ccatgaatgg cgtcggatgt cgcgccagtg cacgcattat gggcgttggc ctcaacacga
      241 ttttacgaca cttaaaaaac tcaggccgca gtcggtaaac tcacgcatac aaccgggcag
      301 tgacgtcatt gtttgcgcgg aaatggacga acagtggggt tacgtcggcg ctaaatcacg
      361 ccagcgctgg ttgttttacg cgtatgacag gatacggagg acggttgtgg cgcatgtatt
      421 cggtgaacgc acgttggcca cgctggagcg tcttctgagc ctgctgtcgg cctttgaggt
      481 cgtggtatgg atgacggatg gctggccgct gtatgaatca cgcctgaagg gagaactgca
      541 cgttatcagc aagcgatata cgcagcgcat tgagcggcat aacctgaatc tgaggcagca
      601 tctggcaagg ctgggcagga agtcactgtc gttctcaaaa tcggtggagc tgcatgacaa
//
LOCUS       DAPHKZ010000331          631 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.336, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000331 DAPHKZ010000000
VERSION     DAPHKZ010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.336"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>631
                     /locus_tag="RH288_004753"
     CDS             <1..>631
                     /locus_tag="RH288_004753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HDV4033694.1"
                     /translation="IPLYRRATNEGIQLFLAGSAGLLQTTEDVQFEPCPGLTAAGRGV
                     VSPENIAFTRWLTYLQDGVLLDEQNCLMLHELWLQSGTGQRRWEGLPDEVRETITVHF
                     TAKRGDWCGFWSNEDVSVWWNRLCDNVLPEKTMPFDLLTVLPTRLDVEVNGFNGGVLN
                     GVPSAYHWYTEQYGVKWPVGYEVNISRQGDNFIQVDFDTPWCQPESNVVA"
BASE COUNT          138 a          147 c          196 g          150 t
ORIGIN      
        1 ataccgcttt atcgccgcgc cacaaatgaa ggtattcagc tatttctggc cggaagtgcc
       61 ggacttctgc agaccactga agatgtgcag tttgaaccgt gccccggact gacggctgcc
      121 ggacgtggtg ttgtatcgcc ggagaatatc gcgttcaccc gctggctgac atacctgcag
      181 gacggtgtac tgctggatga gcaaaactgc ctgatgctgc atgaactctg gctgcagagt
      241 ggtactggcc agcgtcgctg ggaaggatta ccggatgagg tcagagaaac catcaccgtg
      301 catttcaccg ccaaaagagg tgactggtgt ggcttctgga gtaacgagga tgtatcggtg
      361 tggtggaacc gtctgtgtga caatgtactg ccggaaaaaa ccatgccgtt tgacctgctg
      421 acggttctgc ccacccgcct ggatgttgaa gtgaatggct ttaacggtgg tgttctgaac
      481 ggtgttcctt ctgcgtatca ctggtatacg gaacagtatg gcgtgaagtg gcctgtgggg
      541 tatgaggtga atatcagccg tcagggagac aacttcattc aggtggattt cgacacgccg
      601 tggtgtcagc cggaaagcaa cgttgttgca g
//
LOCUS       DAPHKZ010000332          625 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.337, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000332 DAPHKZ010000000
VERSION     DAPHKZ010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.337"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(1..625)
                     /locus_tag="RH288_004754"
                     /pseudo
     CDS             complement(1..625)
                     /locus_tag="RH288_004754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613747.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          159 a          143 c          130 g          193 t
ORIGIN      
        1 cttctctgta atgtttatct ttttccagat aacctgggga ttctccccct aaatcaagct
       61 gtaacgttat tctttcataa cctttatcta tgaggtggtt caacctcgtt gttgaaagag
      121 tttcatccag ttcattgact ttagcttcgc gtagtaaatc agagacaaaa acagagtctt
      181 tcttcgagag taggtttgac aaacgttcca gtccagaggt caccagtgca acggaagatg
      241 tgtttaatcg ggcatcttct tcccatgctc aggaatcttc cataacatag aaattggctt
      301 tatccagata agcaatcagc agcgcaaccg actttaatcg gtcacctttt tgccaatctt
      361 cagcgttaat agtaccagtg ttgattgctt gtataaggag atcaaggtaa agacctaaag
      421 catcattttg tttatggttc cacagctgcg gcttgccttc ttcctgcaca tctgccatca
      481 cgggggagtt gctgtcaaat cggatatgca cagcattcat ttgcacggga attccatcca
      541 gtcgttttgg gttgctaatg acgtcctgca tccgcttaat ctggtcgggc gtagacatat
      601 aatcccacag ggtgagcaga acctt
//
LOCUS       DAPHKZ010000333          600 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.338, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000333 DAPHKZ010000000
VERSION     DAPHKZ010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..600
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.338"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            118..212
                     /locus_tag="RH288_004755"
     tRNA            118..212
                     /locus_tag="RH288_004755"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:152..154,aa:Sec,seq:tca)
BASE COUNT          144 a          153 c          133 g          170 t
ORIGIN      
        1 ataatgcttt cgtgataata cgctgcgtgt attaggcgga aaaaactgat ctgggggatg
       61 tagaaactca aggaagtagc tataatgcgc cccgcctcca tgtagcaatc gaggcgcgga
      121 agatcgtcgt ctccggtgag gcggctggac ttcaaatcca gttggggccg ccagcggtcc
      181 cgggcaggtt cgactcctgt gatcttccgc caaaatgcct ctcctgacgt tctccaaccc
      241 cttgtaatac tgtcaatcca gatattttct actgctcaat attcaatcgg cttcaggaat
      301 acctggtcta aggttttgtg atggacgatg agcggctgaa gaatccgcct gtcggttctt
      361 ctgtcctcga acgcatccgc gatattcacg ccagtatgcg ccgtgtttat ttgcaggtga
      421 tttgcccccc tgctgactct cagccaactg tatcgccatt aaggtgaaga tgttgtttta
      481 ctcgccccag aacacccttt tttatacgac tattctattt ctttaaccgc tggcgaaaaa
      541 aactgactat aaacttcacc aataatcaga ctgccatcaa gattaatttg ttcatttaat
//
LOCUS       DAPHKZ010000334          599 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.339, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000334 DAPHKZ010000000
VERSION     DAPHKZ010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.339"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            216..476
                     /locus_tag="RH288_004756"
     CDS             216..476
                     /locus_tag="RH288_004756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033695.1"
                     /translation="MLEHFGAEASVLDMTIIVRSNPSKVAILEEFLHGTQEKLGIAEK
                     LGRYGLGSAETHVKDFMIRHKKMLGLSDEDVAILKILKDKGL"
BASE COUNT          196 a           95 c          140 g          168 t
ORIGIN      
        1 ctggggttgc agggagggga gcagacttac cggtatgtgc cgaatccttt aagatggata
       61 gatcccttag gattaaataa aggagcttca ttatctaaaa tgatgaatag ctccagtgat
      121 ctcatggggt tgagaaggca gccccagaac ttctggcggc tatatcgcgg aaaagacatt
      181 taataatagc attaccaggc tcagatgaat tcagaatgct tgaacatttt ggagccgaag
      241 cttcggtatt agacatgacg attattgttc gttcaaatcc gagtaaagtc gctattcttg
      301 aagagttttt acatggtaca caagagaaac taggaatagc tgaaaaatta ggacgttatg
      361 gactagggag tgcagaaacg cacgttaagg atttcatgat aagacacaaa aaaatgcttg
      421 ggttatctga tgaggatgta gcaatactca aaatattgaa agacaagggg ttgtgatgaa
      481 tataattctg ccgataaaag atatatttat tattgcggga aacatagttt ttagcgtttt
      541 atacaatgaa catcttgagt tcccatgccg ctgccaatta ctatcttcaa attctgaag
//
LOCUS       DAPHKZ010000335          580 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.340, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000335 DAPHKZ010000000
VERSION     DAPHKZ010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..580
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.340"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            73..>580
                     /locus_tag="RH288_004757"
     CDS             73..>580
                     /locus_tag="RH288_004757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415458.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV4033696.1"
                     /translation="MKKSVLTAFITVVCATSSVMAADDNAITDGSVTFNGKVIAPACT
                     LVAATKDSVVTLPDVSATKLQTNGQVSGVQIDVPIELKDCDTTVTKNATFTFNGTADT
                     TQITAFANQASSDAATNVALQMYMNDGTTAITPDTETGNILLQDGDQTLTFKVDYIAT
                     GKATSGNVN"
BASE COUNT          174 a          105 c          136 g          165 t
ORIGIN      
        1 attattgtta ttattaagtc taatgtcatt taaaggcatt atcatattta cgaagagatc
       61 aggatgataa cgatgaaaaa aagtgtattg acggcgttta taactgtggt atgtgcaacg
      121 tccagcgtta tggctgctga tgataatgct atcacggatg gctcagtaac atttaatggt
      181 aaagttattg ctccagcttg taccctggta gctgcgacga aagattccgt ggtgactttg
      241 ccagatgtta gtgccacgaa gttgcaaacc aatggtcagg tttctggcgt gcaaattgat
      301 gtgccaattg aattaaaaga ttgtgatact accgtaacaa aaaatgcaac gttcaccttt
      361 aatggcactg cggatactac tcagattaca gcgtttgcta accaggcctc atctgatgct
      421 gctacaaacg tggccctgca aatgtatatg aatgatggta caacggccat cacgccagac
      481 acagaaaccg ggaacatttt gttgcaggat ggagatcaga cgttgacttt taaagttgat
      541 tatatcgcta cggggaaagc gacttcaggt aatgtgaatg
//
LOCUS       DAPHKZ010000336          578 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.341, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000336 DAPHKZ010000000
VERSION     DAPHKZ010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.341"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(111..446)
                     /locus_tag="RH288_004758"
     CDS             complement(111..446)
                     /locus_tag="RH288_004758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HDV4033697.1"
                     /translation="MSLPHCPKCNSEYTYEDNGMYICPECAYEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
BASE COUNT          134 a          139 c          142 g          163 t
ORIGIN      
        1 ggtgcgggaa tttgtaggcc tgataagacg cgcaagcgtc gcatcaggca tctggcaccg
       61 ttgccggatg cggcgcgagc gccttatccg gcttaccgat cacaatacaa tcagttcttt
      121 ttcacaaact cagatttcag tttcatcgga ccaaaaccgt cgattttgca atcgatgtta
      181 tggtcgcctt caaccaggcg gatgtttttc actttggtgc caattttcag catcgaagag
      241 ctacctttca ccttcagatc tttaatgatg gtaacgctgt cgccgtcagc cagcagattg
      301 ccgttagcat ctttaacgat cagctcgtcg ctttcctgtg caggttctgc gtcgttccat
      361 tcgtaggcac attccgggca gatgtacatg ccgttatctt cgtaggtgta ttcggagttg
      421 cattttgggc agtgtggtaa tgacatgtgg atttcctcaa aagtcagcag ggcaaaagcg
      481 ccaaaaaacg gcagattgcc gaaaaaggcc gcaattatac acaaaatccc tgagtttgtc
      541 gggggtactg ctgattttag acgacgatcg ttttcatt
//
LOCUS       DAPHKZ010000337          575 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.342, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000337 DAPHKZ010000000
VERSION     DAPHKZ010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.342"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..232
                     /locus_tag="RH288_004759"
     CDS             <1..232
                     /locus_tag="RH288_004759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033698.1"
                     /translation="ENAYLVVPQINYTMDLNIEDSSSEELLSDNTLEKDENSPDNGFE
                     VGEYNTYEAYNSEKQYFTREDYTYDYDLLNAI"
BASE COUNT          183 a          124 c          110 g          158 t
ORIGIN      
        1 agaaaatgct tatctggtcg tcccccaaat taattatact atggatttaa acatagaaga
       61 ctctagctca gaagagttac tttcagataa taccctcgag aaagacgaaa attctccgga
      121 caatggcttt gaggtcgggg aatataacac atatgaagca tataactcag agaagcaata
      181 ttttaccaga gaggactata cgtatgatta cgacctttta aatgcaatat agacttaata
      241 acttcttaca aagtctatta ttaataccgt agatatttat tcatcttacc ctgtgcacca
      301 aaagcaaaaa ctcactgacg cgggtttgaa actgatggca accgcaaaaa tgcctgatgc
      361 gctacgctta tcaggcctac gccatctctg caatatattg aatttgcgtg cttttgtagg
      421 caggataagg cgttcacgcc gcatccggca tgaataaagc gcactcaaca atctgaaacc
      481 cgccggaacg gtttattacg tacatcaggt aaaactgacc gataagccgc tttcttttgg
      541 gtatagtgtc gtggacagtc attcatcttt ctgcc
//
LOCUS       DAPHKZ010000338          575 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.343, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000338 DAPHKZ010000000
VERSION     DAPHKZ010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.343"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            38..409
                     /locus_tag="RH288_004760"
     CDS             38..409
                     /locus_tag="RH288_004760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004924490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV4033699.1"
                     /translation="MQLRYDDKQFHTTVIKDVLLWIEHNLDQSLLLDDVANKAGYTKW
                     YFQRLFKKVTGVTLASYIRARRLTKAAVELRLTKKTILEIALKYQFDSQQSFTRRFKY
                     IFKVTPSYYRRNKLWELEAMH"
     gene            complement(419..>575)
                     /locus_tag="RH288_004761"
     CDS             complement(419..>575)
                     /locus_tag="RH288_004761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HDV4033700.1"
                     /translation="TVRNRNVLSTVRLGMEVLRHSGYTITREDLLVAATLLAQNLFTH
                     GYALGKL"
BASE COUNT          177 a          103 c          120 g          175 t
ORIGIN      
        1 tgaacagcat tctcgctatc aaaataaagc taataacatc caattaagat atgatgataa
       61 gcagtttcat acaacggtta tcaaagatgt tctattatgg attgaacata atttagatca
      121 gtctttactg cttgatgatg tggcgaataa agcgggttat accaagtggt attttcagcg
      181 gctgttcaaa aaagtaacag gggtcacact ggctagctat attcgtgctc gtcgtttgac
      241 gaaagcggct gttgagttga ggttgacgaa aaaaactatc cttgagatcg cattaaaata
      301 tcaatttgat tcccaacaat cttttacacg tcgatttaag tacattttta aggttacacc
      361 aagttattat cggcgtaata aattatggga attggaggca atgcactgag agatcccctc
      421 ataatttccc caaagcgtaa ccatgtgtga ataaattttg agctagtagg gttgcagcca
      481 cgagtaagtc ttcccttgtt attgtgtagc cagaatgccg caaaacttcc atgcctaagc
      541 gaactgttga gagtacgttt cgatttctga ctgtg
//
LOCUS       DAPHKZ010000339          557 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.344, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000339 DAPHKZ010000000
VERSION     DAPHKZ010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.344"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..>557)
                     /locus_tag="RH288_004762"
     CDS             complement(<1..>557)
                     /locus_tag="RH288_004762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS domain-containing protein"
                     /protein_id="HDV4033701.1"
                     /translation="HLYHCDHRGLPLALISEDGNTAWSAEYDEWGNQLNEENPHHVYQ
                     PYRLPGQQHDEESGLYYNRHRYYDPLQGRYITQDPMGLKGGWNLYQYPLNPLQQIDPM
                     GLLQTWDDARSGACTGGVCGVLSRIIGPSKFDSTADAALDALKETQNRSLCNDMEYSG
                     IVCKDTNGKYFASKAETDNLRKESY"
BASE COUNT          143 a          149 c          104 g          161 t
ORIGIN      
        1 gatatgactc ctttcttaaa ttatcagttt ctgccttaga tgcaaaatat tttccattag
       61 tatctttaca gacaatacca gagtattcca tatcattaca tagagatcta ttctgcgttt
      121 ctttcaaagc atctaacgca gcatctgcag tactatcaaa tttacttggt cctattatac
      181 gtgaaagaac accacaaact ccccccgtac atgctccaga tctggcatca tcccaagtct
      241 gcaataatcc catagggtca atttgttgta gtggatttaa aggatactga tataaattcc
      301 atcccccttt caaccccatc gggtcctgag taatataccg cccctgcaac ggatcgtagt
      361 accggtgacg gttatagtac agccctgatt cctcatcatg ctgctgccct ggcagacggt
      421 acggctgata cacatgatgc gggttctcct cattaagctg gttgccccat tcatcatatt
      481 ccgcgctcca cgccgtattg ccgtcttcgc tgataagcgc cagcggcagt ccccggtggt
      541 cgcagtgata aagatga
//
LOCUS       DAPHKZ010000340          532 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.345, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000340 DAPHKZ010000000
VERSION     DAPHKZ010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..532
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.345"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            86..334
                     /locus_tag="RH288_004763"
     CDS             86..334
                     /locus_tag="RH288_004763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001349157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033702.1"
                     /translation="MFIYASGGNGGSAGGACANTSRLQGYVGGTLISVNASNNPAYGK
                     TAFISFAVPAGTSYQITSYPTENTSCGAGVFSVFGYQT"
     gene            complement(331..>532)
                     /locus_tag="RH288_004764"
     CDS             complement(331..>532)
                     /locus_tag="RH288_004764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012565250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033703.1"
                     /translation="TIGGKLKVTQLSTTGYLGQFDFCAIARMGNAEDAHYCQVVESPA
                     GSRKWYKYEHKTGCIASCVTLN"
BASE COUNT          135 a          118 c          126 g          153 t
ORIGIN      
        1 gacttctggt tcgctcaatg gttcttacac aaacttaggt tcacatagag gttcattctc
       61 agggcggaat tcagggggca gtacattgtt tatttatgca tctggaggta atggaggatc
      121 tgccggaggt gcatgtgcaa atacatcccg actgcaggga tatgttggtg ggacgctaat
      181 tagcgtgaat gccagcaata accctgcata tggaaaaaca gcctttatca gctttgctgt
      241 acctgcaggt acttcctatc agataacatc ctatccaaca gaaaatacat catgtggtgc
      301 cggggtattt tcagtatttg gatatcaaac ttaattgagc gttacacacg acgcaataca
      361 acctgtctta tgctcgtatt tgtaccattt gcgtgaacct gctgggctct caactacctg
      421 gcagtagtgg gcatcctctg cgttgcccat tctggcaatg gcacagaagt cgaattgccc
      481 cagataacct gtggtggaaa gctgagtaac tttgagtttt ccacctattg tc
//
LOCUS       DAPHKZ010000341          522 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.346, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000341 DAPHKZ010000000
VERSION     DAPHKZ010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.346"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..>522)
                     /locus_tag="RH288_004765"
     CDS             complement(<1..>522)
                     /locus_tag="RH288_004765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SopA family protein"
                     /protein_id="HDV4033704.1"
                     /translation="CACDFLMDKDAQGYIDLSDLDLTSCHFKGDVISKVSFLSSNLQH
                     VTFECKEIGDCNFTTATVDNVIFKCRRLHNVIFIKASGECVDFSKNILDTVDFSRSQL
                     THSNFRECQIRNSNFDNCYLYASHFTRAEFLSDKEISFIKSNLTAVMFDHVRISTGNF
                     KDSVTQLMVLSID"
BASE COUNT          185 a           99 c           78 g          160 t
ORIGIN      
        1 taatcaatag ataataccat tagttgtgta acgctgtctt taaaattccc tgtcgatatt
       61 cgcacatgat caaacataac agctgtcaaa ttcgatttaa taaatgatat ttctttgtca
      121 gaaagaaatt ctgctctggt gaagtgcgaa gcataaagat aacaattatc gaagtttgaa
      181 tttctaatct gacattcgcg aaaattacta tgagtaagct ggctccgcga gaagtcaact
      241 gtatcaagaa tatttttgct aaaatcgaca cattcaccac tcgctttgat aaaaatcaca
      301 ttgtgtaaac gtcgacattt aaatatgaca ttatcaactg ttgcagtagt aaaattgcaa
      361 tccccaattt ctttacattc gaatgttaca tgttgtagat tagatgataa aaaagacacc
      421 ttcgatataa cgtcaccttt aaaatgacaa cttgttaaat ccaaatcaga caggtcgata
      481 tacccctgcg cgtctttatc catcagaaaa tcacaagcac at
//
LOCUS       DAPHKZ010000342          518 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.347, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000342 DAPHKZ010000000
VERSION     DAPHKZ010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.347"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>518
                     /locus_tag="RH288_004766"
     CDS             <1..>518
                     /locus_tag="RH288_004766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV4033705.1"
                     /translation="QSEDEGLITLWHYDASDRITHRTVNGDPAEQWQYDEHGWLTTLS
                     HTSEGHRVSVHYGYDDKGRLTGERQTVENPETGELLWHHETGHAYNEQGLANRVTPDS
                     LPPVEWLTYGSGYLAGMKLGGTPLLEFTRDRLHRETVRSFGSMAGSNAAYKLTSTYTP
                     AGQLQSQHLNSLV"
BASE COUNT          118 a          158 c          170 g           72 t
ORIGIN      
        1 cagagtgaag atgaggggct tatcaccctc tggcactacg atgcgtcgga ccgcatcacg
       61 caccggacgg tgaacggcga cccggcagag cagtggcagt atgatgagca cgggtggtta
      121 accaccctca gccataccag tgaaggccac cgcgtgtcgg tccactacgg ctatgacgat
      181 aaaggccgcc tgaccggcga acgccagacg gtggagaacc cggagacggg ggaactgctg
      241 tggcaccatg agaccggaca tgcgtacaac gaacaggggc tggcaaaccg cgtcacgccg
      301 gacagtctgc cgccggtgga gtggctgacc tacggcagcg gctatcttgc gggcatgaag
      361 ctgggcggga cgccgctgct ggagttcacg cgcgaccgcc tgcaccgtga gacggtgcgc
      421 agcttcggca gcatggcagg cagtaatgcc gcatataaac tgaccagcac atacaccccc
      481 gcaggccagt tacagagcca gcacctgaac agcctggt
//
LOCUS       DAPHKZ010000343          518 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.348, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000343 DAPHKZ010000000
VERSION     DAPHKZ010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.348"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>518
                     /locus_tag="RH288_004767"
     CDS             <1..>518
                     /locus_tag="RH288_004767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV4033706.1"
                     /translation="QSEDEGLVILWYYDESDRITHRTVNGEPAEQWQYDGHGWLTDIS
                     HLSEGHRVAVHYGYDDKGRLTGECQTVENPETGELLWQHETKHAYNEQGLANRVTPDS
                     LPPVEWLTYGSGYLAGMKLGGTPLLEFTRDRLHRETVRSFGSMAGSNAAYELTSTYTP
                     AGQLQSQHLNSLV"
BASE COUNT          120 a          153 c          170 g           75 t
ORIGIN      
        1 cagagtgagg atgagggact tgtcatcctc tggtactacg atgaatcgga ccgtatcact
       61 caccgcacgg tgaacggcga accggcagag cagtggcagt atgatggcca cggctggctg
      121 acagacatca gccacctgag cgaaggccac cgtgttgccg tccactatgg ctatgacgat
      181 aaaggccgcc tgaccggcga atgccagacg gtggagaacc cggagacggg ggaactgctg
      241 tggcagcatg agacgaaaca cgcatacaac gagcaggggc tggcaaaccg cgtcacgccg
      301 gacagtctgc cgccggtgga gtggctgacc tacggcagcg gctatcttgc gggcatgaag
      361 ctgggcggga cgccgctgct ggagttcacg cgcgaccgcc tgcaccgtga gacggtgcgc
      421 agcttcggca gcatggcagg cagtaatgcc gcatacgaac tgaccagcac atacaccccc
      481 gcaggccagt tacagagcca gcacctgaac agcctggt
//
LOCUS       DAPHKZ010000344          516 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.349, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000344 DAPHKZ010000000
VERSION     DAPHKZ010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.349"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
BASE COUNT          145 a          117 c          116 g          138 t
ORIGIN      
        1 tggaaatcat catcagcgtc gatatggacg aatataaaaa catttacgtt atatcccaaa
       61 aacacacagg tcttagggag gtttaaactg tgtattaaca cctatcgtat tgacgggcgt
      121 gaaatggcag aaacagaagt cgttcctatt gacatgcctg actctaacgg cgagatgact
      181 tggcaagcca aaaactacac acagtattcg tcctacttta tgaagattac ttgcttgaaa
      241 tagcttattg gcaaatggca tatacagtta ttgaaccatt ctgatcttcg gttgtatcgc
      301 acgcagccga ccatgagtta ttggctgatg ggaatgacct ggtaagccat atgtaaccag
      361 ttcgtgaggt gcatattccg ccgccacctg taacacgttt tccagttgga caagtagctg
      421 ttgctccagg aaagcgccaa cctgtggcct gtgctgtagc aatttgaagc tcaccagatc
      481 ctacctttct ccaggtaccg gattggcacg taggcc
//
LOCUS       DAPHKZ010000345          516 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.350, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000345 DAPHKZ010000000
VERSION     DAPHKZ010000345.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.350"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..234)
                     /locus_tag="RH288_004768"
     CDS             complement(<1..234)
                     /locus_tag="RH288_004768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033707.1"
                     /translation="MTASGTGLGYGEGDESYGYDSCGYLKAQSAGRHRISEETDQYAG
                     GHRLKQAGNTQYDYDAAGRMVSRTRHRDGYRPET"
BASE COUNT           77 a          181 c          144 g          114 t
ORIGIN      
        1 tgtttccggg cggtagccgt cacggtgtct ggtgcggctg accatccggc ctgcggcgtc
       61 atagtcatac tgcgtgtttc cggcctgttt cagccggtgg cctccggcat actggtcagt
      121 ctcttcactt atccggtgcc tgcccgcaga ctgcgccttc aggtagccac aactgtcata
      181 gccataggac tcatcgcctt cgccatagcc cagcccggtg cctgaggctg tcaccgccgt
      241 gacctggccg ttccggtcca gccggtattc ccgccgtgtt tcccgtccgt aatcttcccg
      301 gctggtgaca gccgacacat tgcccgcgct gtcgtaacgg tactcccgta ccagtgaggg
      361 gagcagcccg ccccatgtgg tttcctccgg gaaaaatccg gcgcgctggg tgacaagctg
      421 gctggctgca ttccagccct gctcacaggc aaaaccccgg ttactgtgcc ggaacacttc
      481 acgtcccgcc tcatcacggc tgaacgtcag cgtctc
//
LOCUS       DAPHKZ010000346          508 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.351, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000346 DAPHKZ010000000
VERSION     DAPHKZ010000346.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.351"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>508
                     /locus_tag="RH288_004769"
     CDS             <1..>508
                     /locus_tag="RH288_004769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV4033708.1"
                     /translation="SAQGEQWEYRHDASGRRTEKRCDRKKIRFTYLWDGDSIAEIREY
                     RDDKLYSVRHLVFNGFELISQQFSRVRQAHPSVAPQWVTRTNHAVSDLTGRPLMLFNS
                     EGKTVWRPGQTSLWGLALSLPADTGYPDPRGELDPEAAPGLLYAGQWQDAESGLCYNR
                     FRYYEPETG"
BASE COUNT          113 a          147 c          173 g           75 t
ORIGIN      
        1 gcagcgcaca gggggagcag tgggaatacc gccacgacgc cagcggcaga cgaacagaga
       61 aacgctgcga ccggaagaaa atccgcttca cgtacctgtg ggacggcgac agtattgcgg
      121 aaatccggga ataccgcgat gataaactgt acagcgtacg gcacctggtg tttaacggct
      181 ttgagctgat aagccagcag ttcagccggg tacggcaggc gcatccgtcg gtggccccgc
      241 agtgggtgac gcggacgaat catgcggtga gcgacctgac gggccgcccg ctgatgctct
      301 ttaacagtga aggtaaaacc gtctggcgac cgggacagac cagcctgtgg gggctggcac
      361 tcagcctgcc cgcagacacc ggctacccgg acccgcgcgg ggaactggac ccggaagccg
      421 cccctggcct gctgtatgca ggacagtggc aggatgcgga atccgggctg tgctataacc
      481 ggttccggta ttacgagccg gaaaccgg
//
LOCUS       DAPHKZ010000347          503 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.352, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000347 DAPHKZ010000000
VERSION     DAPHKZ010000347.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.352"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            21..>503
                     /locus_tag="RH288_004770"
     CDS             21..>503
                     /locus_tag="RH288_004770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033709.1"
                     /translation="MFPVSSIGNDISSDLVRRKMNDLPESPTGNNLEALAPGIEKLKQ
                     TSIEMVTLLNTLQPGGKCIITGDFQKELAYLQNVILYNVSSLRLDFLGYNAQIIQRSD
                     NTCELTINEPLKNQEISTGNININCPLKDIYNEIRRLNVIFSCGTGDIVDLSSLDLRN
                     V"
BASE COUNT          176 a           87 c           83 g          157 t
ORIGIN      
        1 tatttataaa ggataaaata atgttccctg tttcatcaat tggtaatgat attagtagtg
       61 atttagtccg tcgaaaaatg aatgaccttc ctgaaagccc aacaggaaat aacctcgaag
      121 cactagcacc aggtatagaa aaactaaaac agacctctat tgaaatggtc actttactta
      181 acacgttaca acctggtgga aaatgcatta tcactggtga ttttcaaaaa gaattagcgt
      241 acttacaaaa tgtaattctt tataatgtct cgtctcttcg tctggatttt ttaggttata
      301 acgcccaaat tattcaacga tcggacaata cttgtgaact taccattaat gaaccgttaa
      361 aaaaccagga aatatccaca ggtaatatca atattaattg cccattaaaa gatatttaca
      421 atgaaatcag gaggttaaac gtaattttta gttgtgggac tggagatatc gttgatctat
      481 cctctctgga cttacgtaat gtc
//
LOCUS       DAPHKZ010000348          475 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.353, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000348 DAPHKZ010000000
VERSION     DAPHKZ010000348.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.353"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..466
                     /locus_tag="RH288_004771"
     CDS             <1..466
                     /locus_tag="RH288_004771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDV4033710.1"
                     /translation="ELTVQSASAQKTPYCVMIMDIDHFKKVNDTWGHPVGDQVIKTVV
                     NIIGKSIRPDDLLARVGGEEFGVLLTDIDTERAKALAERIRENVERLTGDNPEYAIPQ
                     KVTISIGAVVTQENALNPNEIYRLADNALYEAKETGRNKVVVRDVVNFCESP"
BASE COUNT          143 a           91 c          129 g          112 t
ORIGIN      
        1 tgaactgaca gttcaatcag catcagccca aaaaacgcct tattgcgtca tgattatgga
       61 tatcgaccac ttcaaaaaag tcaacgacac ctgggggcat ccggttggcg atcaggtgat
      121 aaaaacagtg gtgaatatca ttgggaaaag catacgacca gatgaccttt tagcgcgcgt
      181 cggcggcgaa gagtttggcg tcttgctgac ggacatcgat actgaacgtg cgaaagcttt
      241 agcggaaagg attcgggaaa atgttgagcg tttaactggc gataatcctg aatacgctat
      301 accacaaaaa gtgacgatta gtattggcgc tgttgtgact caggaaaatg cgttaaaccc
      361 aaatgagatc tatcgactgg ctgataacgc actttacgag gcgaaagaga ccgggcgtaa
      421 taaggtggtt gtgagggatg tggtgaattt ttgtgagtca ccataaagcg gcatt
//
LOCUS       DAPHKZ010000349          474 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.354, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000349 DAPHKZ010000000
VERSION     DAPHKZ010000349.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.354"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..306)
                     /locus_tag="RH288_004772"
     CDS             complement(<1..306)
                     /locus_tag="RH288_004772"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV4033711.1"
                     /translation="MANAILWYEIKNIGSFEDEGGFVDLTTTAKDKKKELWVDVDGHK
                     VNLITAIMGANASGKTTLLKPMSFLSWFFWSIPAKVTDYLYLNINRPFTKPGMIKICF
                     "
BASE COUNT          156 a          107 c           75 g          136 t
ORIGIN      
        1 aaaacatatt ttaatcatac ctggttttgt aaaaggccga ttaatgttta aatacagata
       61 atcagttact tttgctggta tagaccaaaa aaaccaactc aagaaagaca ttggtttaag
      121 gagtgttgtc ttaccggagg cgttcgcccc catgatagca gtaatcagat tgaccttgtg
      181 tccatctaca tctacccaca gttctttttt cttatcttta gctgtagtag ttaggtctac
      241 gaacccacct tcatcttcaa agctaccgat attcttaatc tcataccaaa gtatagcgtt
      301 agccataacc cctcttttta tacaaaaaaa tgttcaaaat cgccacatgc tgagtttata
      361 gcaggaagcg tatatagcaa gcaaaaaaac atagacacga tttagttaaa tcgataacgg
      421 ccggaaatca ttcaattccc gcactatcga acgttcacca gccaaccgca gcac
//
LOCUS       DAPHKZ010000350          468 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.355, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000350 DAPHKZ010000000
VERSION     DAPHKZ010000350.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.355"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            94..>468
                     /locus_tag="RH288_004773"
     CDS             94..>468
                     /locus_tag="RH288_004773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome protein TraM"
                     /protein_id="HDV4033712.1"
                     /translation="MAKVNLYISNDAYEKINAIIEKRRQEGAREKDVSFSATASMLLE
                     LGLRVHEAQMERKESAFNQTEFNKLLLECVVKTQSSVAKILGIESLSPHVSGNPKFEY
                     ANMVEDIREKVSSEMERFFPKND"
BASE COUNT          146 a           72 c          109 g          141 t
ORIGIN      
        1 taggggcgct gctagcggtg cgtccctgtt tgcattatga attttagtgt ttcgaaatta
       61 actttatttt atgttcaaaa aaggtaatct ctaatggcta aggtgaacct gtatatcagc
      121 aatgatgcct atgaaaaaat aaatgcgatt attgagaagc gtcgacagga aggggcaagg
      181 gaaaaagatg tcagtttttc agcaacagct tcaatgcttc ttgaactggg gcttcgtgta
      241 catgaggctc agatggagcg taaagagtct gcatttaatc agactgagtt taataaattg
      301 cttcttgaat gcgttgtaaa aacacaatca tcagtagcga aaattttggg tattgagtct
      361 ctcagtcctc atgtctccgg aaatccaaag tttgaatatg ccaatatggt tgaagatatc
      421 agggagaagg tatcatctga gatggaacga ttttttccaa aaaatgat
//
LOCUS       DAPHKZ010000351          458 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.356, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000351 DAPHKZ010000000
VERSION     DAPHKZ010000351.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.356"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..87
                     /locus_tag="RH288_004774"
     CDS             <1..87
                     /locus_tag="RH288_004774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001697964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI-like family protein"
                     /protein_id="HDV4033713.1"
                     /translation="GARNDKDKERILSLLEEIWQDDSWLPAA"
     gene            84..>458
                     /gene="umuD"
                     /locus_tag="RH288_004775"
     CDS             84..>458
                     /gene="umuD"
                     /locus_tag="RH288_004775"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HDV4033714.1"
                     /translation="MSTVYHRPADPSGDDSYVRPLFADRCQAGFPSPATDYAEQELDL
                     NSYCISRPAATFFLRASGESMNQSGVQNGDLLVVDRAEKPQHGDIVIAEIDGEFTVKR
                     LLLRPRPALEPVSDSPEFRTLYP"
BASE COUNT          100 a          131 c          130 g           97 t
ORIGIN      
        1 ggagcccgca acgacaagga taaagaacgt atcctgtctc tgctggaaga aatctggcag
       61 gacgacagct ggctgcctgc agcatgagta ccgtttatca ccgtccggct gacccttcag
      121 gcgatgacag ttacgtgcga ccgttgtttg ccgatcgttg ccaggccggt tttccttcgc
      181 ctgccactga ttatgctgag caggaactgg atctgaacag ctattgcatc agcagacctg
      241 cagccacctt ctttctgcgc gccagcggtg aatcgatgaa ccagtctggc gtgcagaatg
      301 gtgatctgct ggtagtggac agggccgaaa aaccacaaca cggggacatc gttatcgctg
      361 agatcgacgg tgagttcacc gtcaaacgac tgctgttgcg cccacgcccg gcactggagc
      421 cggtttcaga cagcccggag ttccgcacac tgtatccg
//
LOCUS       DAPHKZ010000352          451 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.357, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000352 DAPHKZ010000000
VERSION     DAPHKZ010000352.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.357"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>451
                     /locus_tag="RH288_004776"
     CDS             <1..>451
                     /locus_tag="RH288_004776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CHASE9 sensor domain-containing protein"
                     /protein_id="HDV4033715.1"
                     /translation="IQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQE
                     QVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSWNPAYNCFDRPGKKCISFTLHIN
                     GKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKN"
BASE COUNT          134 a           83 c          102 g          132 t
ORIGIN      
        1 agattcaacg cgccgtgatt cttaaaatgg aaatgatgcc atttttagac tcggtgggac
       61 tggtacttga tgataataaa tattatcttt tttcgcggag ggcgaatgat aaaatcgttg
      121 tttatcatca ggaacaagta aatggaccgc ttgtcgacga gtcagggcgg gttatttttg
      181 ccgattttaa cccatcgaaa cgaccgtggt cggtggcttc agatgactct aacaacagct
      241 ggaatccggc atacaattgc tttgatcgtc cgggtaaaaa atgtatctct tttacgctac
      301 acatcaacgg caaagatcac gatttgttag cggtggataa aattcatgtc gatttaaact
      361 ggcgatatct gaacgagtat cttgatcaaa tcagcgctaa tgatgaagtt ctatttttga
      421 aacaaggcca tgagatcatt gccaagaatc a
//
LOCUS       DAPHKZ010000353          448 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.358, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000353 DAPHKZ010000000
VERSION     DAPHKZ010000353.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.358"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..403)
                     /locus_tag="RH288_004777"
     CDS             complement(<1..403)
                     /locus_tag="RH288_004777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV4033716.1"
                     /translation="MYWIINDNIEFWPEHRKLISVHNADLNVVLTTPASRCLSLLLEA
                     FPDVVAQQDFFTRVWEEEGMRVPTNTLYQNISIIRRGFRAVGDTTHSLIATVPRRGFK
                     IHNDINIQNHVINSSTDAHTHNAPPAIKVNAG"
BASE COUNT          126 a           86 c           99 g          137 t
ORIGIN      
        1 atcccgcatt aacttttatg gcaggtgggg cattgtgtgt atgtgcgtct gttgacgagt
       61 ttattacatg attttgtatg ttaatgtcat tatggatctt gaatcctctt ctcggcacgg
      121 ttgcaattag cgagtgggta gtatcaccaa cagcgcgaaa tccgcgtctg ataatggata
      181 tgttctgata taacgtgtta gtaggcacac gcataccttc ttcttcccag actctggtga
      241 aaaaatcttg ttgtgcaacc acatcaggaa aagcttcaag tagaagtgat aaacatcgac
      301 tggctggcgt tgtcagaacg acgttaagat cggcgttatg taccgatatt aattttcggt
      361 gctcaggcca gaactcgata ttatcgttaa taatccagta catacgtcaa taaacactaa
      421 atcaatcgaa atggagatca catagttt
//
LOCUS       DAPHKZ010000354          447 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.359, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000354 DAPHKZ010000000
VERSION     DAPHKZ010000354.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.359"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>447
                     /locus_tag="RH288_004778"
     CDS             <1..>447
                     /locus_tag="RH288_004778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001507563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDV4033717.1"
                     /translation="HFTPNIVPDTLLSQGRTKYILYVSRFEPYKNHLNLLRAYASLPD
                     SLKKKYHLVLVGESMEPAYSECQQFVEENNLQGQVIFKGKVAYEDLPSVYKSAALFVY
                     PSSCENCPNILLEAIGCGLPVIASKTEPMPEFAKDSALYFDENDYN"
BASE COUNT          141 a           81 c           77 g          148 t
ORIGIN      
        1 acattttact cctaacattg tacctgatac attattaagc caaggtagga caaaatacat
       61 cctttatgta tctcgctttg aaccatataa gaatcatttg aatctattaa gggcatatgc
      121 atccttgcct gattctctga aaaaaaaata tcatctggtt cttgttggtg aatcaatgga
      181 acccgcttat tctgaatgcc aacaatttgt tgaagaaaat aaccttcaag gtcaggttat
      241 ttttaaaggg aaagtagcat atgaggatct tccgtctgtg tataaatctg ctgcattatt
      301 tgtctaccct tcctcttgtg agaattgtcc taatatactc ctagaagcta ttggatgcgg
      361 gcttccagta atagcatcta aaactgaacc aatgcctgaa tttgcgaaag attcggcatt
      421 atatttcgat gaaaatgatt ataatga
//
LOCUS       DAPHKZ010000355          441 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.360, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000355 DAPHKZ010000000
VERSION     DAPHKZ010000355.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.360"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(17..373)
                     /locus_tag="RH288_004779"
     CDS             complement(17..373)
                     /locus_tag="RH288_004779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDV4033718.1"
                     /translation="MQWYLSVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLIL
                     GLELPYLSMLYLLATFLPVLALAIRRLHDTDRSGAWALLFFVPFIGWLVLLVFFCTEG
                     TSGSNRYGNDPKFGSN"
BASE COUNT          158 a           95 c           94 g           94 t
ORIGIN      
        1 cgtcccaatt ctaagattaa tttgaaccaa acttcggatc gtttccgtaa cgattgctgc
       61 cagaagtacc ttctgtgcag aaaaaaacca gaagcacgag ccagccaata aacggaacaa
      121 aaaagagcaa ggcccaggca cctgaacggt cggtatcgtg taagcgacgg atagcaagcg
      181 caaggacggg aaggaaggtt gccagcaaat aaagcataga cagatatgga agctccagac
      241 ctaaaatcaa ttgaatgaca ttgataatag cgccgacgat ggcgttaatc agagtaaaca
      301 tccagtactc tttacgacgt gcgcgaccag agaaaccaac ataatttttt aatacggaca
      361 aataccactg cataaaaaca tccctttaat taaaagtgac gaaagtctat tccgggtatt
      421 gtgtaaatgc tattcgtatc t
//
LOCUS       DAPHKZ010000356          428 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.361, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000356 DAPHKZ010000000
VERSION     DAPHKZ010000356.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.361"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..347)
                     /gene="traJ"
                     /locus_tag="RH288_004780"
     CDS             complement(<1..347)
                     /gene="traJ"
                     /locus_tag="RH288_004780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer transcriptional regulator
                     TraJ"
                     /protein_id="HDV4033719.1"
                     /translation="MYPMDRIQQKHARQIDLLENLTAVIQDYPNPACIRDETGKFIFC
                     NTLFHESFLTQDQSAEKWLLSQRDFCELISVTEMEAYRNEHTHLNLVEDVFIQNRFWT
                     ISVQSFLNGHRNI"
BASE COUNT          132 a           88 c           80 g          128 t
ORIGIN      
        1 ataatatttc tgtgtccatt aagaaatgac tggacagata ttgtccagaa tctgttctga
       61 ataaaaacat cctctacaag attaagatgc gtatgctcat tcctgtatgc ttccatctct
      121 gtgacagaga tcaattcaca aaaatctctc tgcgacagaa gccatttttc agcactttga
      181 tcttgtgtaa gaaatgactc atgaaacagc gtattgcaaa aaataaattt tccagtttcg
      241 tccctgatac aggctggatt tggataatcc tgaataactg ccgtcagatt ttccagcaga
      301 tctatttgac gagcatgttt ttgttgaata cgatccatcg gatacatagg aacctcctca
      361 caaaggattc tatggacagt cgatgcaggg aggagagaac tccctgcatc ggcgattttc
      421 aaattcaa
//
LOCUS       DAPHKZ010000357          426 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.362, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000357 DAPHKZ010000000
VERSION     DAPHKZ010000357.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.362"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..>426)
                     /locus_tag="RH288_004781"
     CDS             complement(<1..>426)
                     /locus_tag="RH288_004781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HDV4033720.1"
                     /translation="AALWQALPEELRLSPHRYLATNSPQGPWWLLGWCERVPEADEVL
                     PAPLPPYRVLTGLVDRFGRTQTFHREAAGEFSGEITGVTDGAGRHFRLVLTTQAQRAE
                     EARQQAISGGTEPSAFPDTLPGYTEYGRDNGIRLSAVWLT"
BASE COUNT           71 a          151 c          134 g           70 t
ORIGIN      
        1 gtcagccaca cggcagacag acggatgccg ttgtcccggc catattcggt gtaacccggc
       61 agggtatcag gaaaagcgga cggttccgtc ccgccggaaa tggcctgctg ccgggcttct
      121 tctgcccgct gcgcctgcgt ggtcagtacc agccggaagt gacgcccggc accatccgtc
      181 acgccggtga tttcgccgct gaattcaccg gcggcttcgc ggtggaacgt ctgtgtgcgc
      241 ccgaagcggt ccaccagccc ggtcagtacc cggtacggcg gcagcggcgc aggcagcacc
      301 tcatccgctt ccggcacccg ctcacaccag ccgagcagcc accacggccc ctgcggactg
      361 tttgtcgcca gataacgatg cggacttaag cggagttctt ccggcagcgc ctgccagagt
      421 gcggcc
//
LOCUS       DAPHKZ010000358          416 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.denovo.363, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000358 DAPHKZ010000000
VERSION     DAPHKZ010000358.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.denovo.363"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            106..>416
                     /locus_tag="RH288_004782"
     CDS             106..>416
                     /locus_tag="RH288_004782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001581562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidylate deaminase"
                     /protein_id="HDV4033721.1"
                     /translation="MKEKKFVSELFLENGQFILVGLTGRTGSGCTTTANILENEKTVF
                     PDVSKLQGFYKGLDVHRYNIVKKFAENHWENFYSIKVSDLISAYLLMLTVEEASEFIL
                     SS"
BASE COUNT          138 a           66 c           80 g          132 t
ORIGIN      
        1 gctctgccgc caaagtgccg ccattacatc aagcatctag aataaaatta gttaataaat
       61 tataattaat atgctaattg ttcttgcatt cataagtggg acgtgatgaa agaaaaaaaa
      121 ttcgttagtg agcttttcct tgaaaatggg cagtttattt tagtcggttt gacaggtcga
      181 actggttctg gttgcacaac aacagctaat attcttgaaa acgaaaaaac agtcttccct
      241 gatgtaagta aattacaggg gttttacaag ggattggatg tccatcgtta taatatagtt
      301 aaaaaattcg cagaaaatca ctgggaaaat ttttactcaa ttaaggtgag tgacctaatc
      361 tcagcgtatc ttctgatgtt aacagttgag gaagcttctg aattcattct atcatc
//
LOCUS       DAPHKZ010000359         9970 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.guided.149, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000359 DAPHKZ010000000
VERSION     DAPHKZ010000359.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9970
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.guided.149"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..422)
                     /locus_tag="RH288_004783"
     CDS             complement(<1..422)
                     /locus_tag="RH288_004783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV4033722.1"
                     /translation="MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVA"
     gene            complement(641..1618)
                     /gene="epmA"
                     /locus_tag="RH288_004784"
     CDS             complement(641..1618)
                     /gene="epmA"
                     /locus_tag="RH288_004784"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HDV4033723.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            1943..3751
                     /gene="frdA"
                     /locus_tag="RH288_004785"
     CDS             1943..3751
                     /gene="frdA"
                     /locus_tag="RH288_004785"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HDV4033724.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERSATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            3744..4478
                     /gene="frdB"
                     /locus_tag="RH288_004786"
     CDS             3744..4478
                     /gene="frdB"
                     /locus_tag="RH288_004786"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HDV4033725.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            4489..4884
                     /gene="frdC"
                     /locus_tag="RH288_004787"
     CDS             4489..4884
                     /gene="frdC"
                     /locus_tag="RH288_004787"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDV4033726.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            4895..5254
                     /gene="frdD"
                     /locus_tag="RH288_004788"
     CDS             4895..5254
                     /gene="frdD"
                     /locus_tag="RH288_004788"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDV4033727.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            5317..6450
                     /locus_tag="RH288_004789"
     CDS             5317..6450
                     /locus_tag="RH288_004789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDV4033728.1"
                     /translation="MFKTTLCALLITASCSTFAAPQKINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPATKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAETYGVKSTIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSGNKIALAARPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNALQ"
     gene            6539..7072
                     /gene="blc"
                     /locus_tag="RH288_004790"
     CDS             6539..7072
                     /gene="blc"
                     /locus_tag="RH288_004790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HDV4033729.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDREMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(7069..7386)
                     /gene="sugE"
                     /locus_tag="RH288_004791"
     CDS             complement(7069..7386)
                     /gene="sugE"
                     /locus_tag="RH288_004791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDV4033730.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(7568..7714)
                     /gene="ecnB"
                     /locus_tag="RH288_004792"
     CDS             complement(7568..7714)
                     /gene="ecnB"
                     /locus_tag="RH288_004792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HDV4033731.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            complement(7825..7950)
                     /gene="ecnA"
                     /locus_tag="RH288_004793"
     CDS             complement(7825..7950)
                     /gene="ecnA"
                     /locus_tag="RH288_004793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HDV4033732.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            complement(8002..8568)
                     /gene="efp"
                     /locus_tag="RH288_004794"
     CDS             complement(8002..8568)
                     /gene="efp"
                     /locus_tag="RH288_004794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDV4033733.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            8610..9638
                     /gene="epmB"
                     /locus_tag="RH288_004795"
     CDS             8610..9638
                     /gene="epmB"
                     /locus_tag="RH288_004795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HDV4033734.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQDEFVVASGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITDALVERFSHSTL
                     QILLVNHINHANEIDETFRQAMAKLRRVGVTLLNQSVLLRDVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
BASE COUNT         2555 a         2565 c         2524 g         2326 t
ORIGIN      
        1 catgccacag ccagcagacc aaccacctgc gtaggctcca gtccggcaat acgccagtgc
       61 tgggtcatgt cgctaccata gaggaatgtt gagaacggta cccaaacttt cgcggaggta
      121 ctcaccatcc agatgatata agaggaaaac cacataaacg taccaatgaa ggcaaaacgt
      181 ggtccgacac tattattcat ccaggaatag ataccgcctt cttctttgcg ataagcagct
      241 cccatttcag ccatcattaa ggcgaatgga ataaagaata acaatgcaga aaatatataa
      301 aagggaatcg cactataacc cattaagtaa taagccgatg ggctattggc aaatccaaat
      361 acggaagtaa agatcatcaa tatgagtcct atcagactca tcttttttat cgtgtgaggc
      421 atgaaaccat ccttcatttc agcgcgtgta taacacgtgc ccactgaact gcactgcgca
      481 acattgagca ggcagcgtaa aaaccaatac agaattgata cctggatgat atcaaatatc
      541 cagtcttaaa ttgtggcctt taacggaaaa atgaaaacat atgctacaga atggcgctta
      601 tcacgccatt cttcgctgtt aattcagtaa tttttcagaa ttatgcccgg tcaacgctaa
      661 aggcgatgac ttcagccagt gtctccgcgc ccagcgccaa catcaccaga cgatcaacac
      721 ctaatgccac gccggaacag tcaggcatac cgactttcaa ggcttcaatc agattctggt
      781 caatggggtg ctgcggcaaa ccgcgcgccg cgcgcttacg gttatcttgt tcaaagcgtt
      841 gttgctgctc acgggcatcc gtcaattcat ggaaaccatt cgccagctca atacctttat
      901 aataaacctc aaagcgttca gcgacccgat gatcttcggt actgatttgc gccagtgatg
      961 cctggctggc tggaaagtgg tacacaaagg tcggtttttc tttgccaata tttggctcta
     1021 cgccaaaggt aaacagcaat tgtagcagcg tgtcgcggtc ttcttcggta tcagcaacat
     1081 tgctcaaatc cagtttcgct gcgacttccc gcagttgcgt tttgtcggca gagagcgggt
     1141 caatttccag ataacgcaag aaagcttgtt gataagaaag gctttctgct gccgggcagt
     1201 ccagcacctg ttgtaagaga tcgtccacct cgttcatcaa ccggtacata tcatagtgcg
     1261 gtcgatacca ctccagcata gtgaactcag ggttgtgata acgccccatc tcttcattac
     1321 ggaagctgcg gcacagctgg aataccggcc cacaaccggc aaccagcagg cgtttcatat
     1381 ggtattccgg gctggtcatt aaccagagat tcatcccctg cgaatgcccg gggcctacga
     1441 aacgtgtctc aaacgggacc aaatgaatat cggttaccgt cgcctggctc atacaaggcg
     1501 tctccacctc cagcactcca cgatcggcaa agaaacgacg gatctccgcc ataatcgccg
     1561 cgcgttttaa taagttagga atggatgcgc tcggctgcca ggatgccgtt tcgctcatag
     1621 ttaaatctcc agtttttgac aagggcacga agtctactcg caacgcgacg gcgagacaaa
     1681 ttttacgcag gaatcaaaca gcggtgggca gtgactaaaa aaagcacgat ctgatggttt
     1741 agtaattaaa ttaatcatct tcagtgataa tttagccctc ttgcgcacta aaaaaatcga
     1801 tctcgtcaaa tttcagactt atccatcaga ctatactgtt gtacctataa aggagcagtg
     1861 gaatagcgtt cgcagaccgt aactttcagg tacttaccct gaagtacgtg gctgtgggat
     1921 aaaaacaatc tggaggaatg tcgtgcaaac ctttcaagcc gatcttgcca ttgtaggcgc
     1981 cggtggcgcg ggattacgtg ctgcaattgc tgccgcgcag gcaaatccga atgcaaaaat
     2041 cgcactaatc tcaaaagtat acccgatgcg tagccatacc gttgctgcag aagggggctc
     2101 cgccgctgtc gcgcaggatc atgacagctt cgaatatcac tttcacgata cagtagcggg
     2161 tggcgactgg ttgtgtgagc aggatgtcgt ggattatttc gtccaccact gcccaaccga
     2221 aatgacccaa ctggaactgt ggggatgccc atggagccgt cgcccggatg gtagcgtcaa
     2281 cgtacgtcgc ttcggcggca tgaaaatcga gcgcacctgg ttcgccgccg ataagaccgg
     2341 cttccatatg ctgcacacgc tgttccagac ctctctgcaa ttcccgcaga tccagcgttt
     2401 tgacgaacat ttcgtgctgg atattctggt tgatgatggt catgttcgcg gcctggtagc
     2461 aatgaacatg atggaaggca cgctggtgca gatccgtgct aacgcggtcg ttatggctac
     2521 tggcggtgcg ggtcgcgttt atcgttacaa caccaacggc ggcatcgtta ccggtgacgg
     2581 tatgggtatg gcgctaagcc acggcgttcc gctgcgtgac atggaattcg ttcagtatca
     2641 cccaaccggt ctgccaggtt ccggtatcct gatgaccgaa ggctgccgcg gtgaaggcgg
     2701 tattctggtc aacaaaaatg gctaccgtta tctgcaagat tacggcatgg gcccggaaac
     2761 tccgctgggc gagccgaaaa acaaatatat ggaactgggt ccacgcgaca aagtttctca
     2821 ggccttctgg cacgaatggc gtaaaggcaa caccatctcc acgccgcgtg gcgatgtggt
     2881 ttatctcgac ctgcgtcacc tcggcgagaa aaaactgcat gaacgtctgc cgttcatctg
     2941 cgaactggcg aaagcgtacg ttggcgtcga tccggttaaa gaaccgattc cggtacgtcc
     3001 gaccgcacac tacaccatgg gcggtatcga aaccgatcag aactgtgaaa cccgcattaa
     3061 aggtctgttc gccgtgggtg aatgttcctc tgttggtctg cacggtgcaa accgtctggg
     3121 ctccaactcc ctggcggaac tggtggtctt cggccgtctg gccggtgaac aagcgacaga
     3181 gcgttcagca actgccggta atggcaacga agcggcaatt gaagcgcagg cagctggcgt
     3241 tgaacaacgt ctgaaagatc tggttaacca ggatggcggc gaaaactggg cgaagatccg
     3301 cgacgaaatg ggcctggcaa tggaagaagg ttgcggtatc taccgtacgc cggaactgat
     3361 gcagaaaacc atcgacaagc tggcagaact gcaggaacgc ttcaagcgcg tgcgcatcac
     3421 cgacacctcc agcgtgttca acaccgacct gctctacacc attgaactgg gccacggtct
     3481 gaacgttgct gaatgtatgg cgcactccgc aatggcacgt aaagagtccc gcggcgcaca
     3541 ccagcgtctg gacgaaggtt gcaccgagcg tgacgacgtc aacttcctca aacacaccct
     3601 cgccttccgc gatgctgatg gcacgactcg cctggagtac agcgacgtga agattactac
     3661 gctgccgcca gctaaacgcg tttacggtgg cgaagcggat gcagccgata aggcggaagc
     3721 agccaataag aaggagaagg cgaatggctg agatgaaaaa cctgaaaatt gaggtggtgc
     3781 gctataaccc ggaagtcgat accgcaccgc atagcgcatt ctatgaagtg ccttatgacg
     3841 caactacctc attactggat gcgctgggct acatcaaaga caacctggca ccggacctga
     3901 gctaccgctg gtcctgccgt atggcgattt gtggttcctg cggcatgatg gttaacaacg
     3961 tgccaaaact ggcatgtaaa accttcctgc gtgattacac cgacggtatg aaggttgaag
     4021 cgttagctaa cttcccgatt gaacgcgatc tggtggtcga tatgacccac ttcatcgaaa
     4081 gtctggaagc gatcaaaccg tacatcatcg gcaactcccg caccgcggat cagggtacta
     4141 acatccagac cccggcgcag atggcgaagt atcaccagtt ctccggttgc atcaactgtg
     4201 gtctgtgcta cgccgcgtgc ccgcagtttg gcctgaaccc agagttcatc ggtccggctg
     4261 ccattacgct ggcgcatcgt tataacgaag atagccgcga ccacggtaag aaggagcgta
     4321 tggcgcagtt gaacagccag aacggcgtat ggagctgtac tttcgtgggc tattgctccg
     4381 aagtctgccc gaaacacgtc gatccggctg cggccattca gcagggcaaa gtagaaagtt
     4441 cgaaagactt tcttatcgcg accctgaaac cacgctaagg agtgcaacat gacgactaaa
     4501 cgtaaaccgt atgtacggcc aatgacgtcc acctggtgga aaaaattgcc gttttatcgc
     4561 ttttacatgc tgcgcgaagg cacggcggtt ccggctgtgt ggttcagcat tgaactgatt
     4621 ttcgggctgt ttgccctgaa aaatggcccg gaagcctggg cgggattcgt cgacttttta
     4681 caaaacccgg ttattgtgat cattaacctg atcactctgg cggcagctct gctgcatacc
     4741 aaaacctggt ttgaactggc accgaaagcg gccaatatca ttgtaaaaga cgaaaaaatg
     4801 ggtccagagc caattatcaa aagtctctgg gcggtaactg tggttgccac catcgtaatc
     4861 ctgtttgttg ccctgtactg gtaaggagcc tgagatgatc aatccaaatc caaagcgttc
     4921 tgacgaaccg gtattctggg gcctcttcgg ggccggtggt atgtggagcg caattattgc
     4981 gccggtgatg atcctgctgg tgggtattct gctgccgctg gggctgtttc cgggtgatgc
     5041 actgagctac gagcgcgttc tggcgttcgc gcagagcttc attggtcgcg tattcctgtt
     5101 cctgatgatc gttctgccgc tgtggtgtgg tttacaccgt atgcaccacg cgatgcacga
     5161 tctgaaaatc cacgtacctg cgggcaaatg ggttttctac ggtctggctg ctatcctgac
     5221 agttgtcacg ctgattggtg tcgttacaat ctaacgcatc gccaatgtaa atccggcccg
     5281 cctatggcgg gccgttttgt atggaaacca gaccctatgt tcaaaacgac gctctgcgcc
     5341 ttattaatta ccgcctcttg ctccacattt gctgcccccc aaaaaatcaa cgatattgtg
     5401 catcgcacaa ttaccccgct tatagagcaa caaaagatcc ccggtatggc ggtggcggta
     5461 atttatcagg gtaaacctta ttactttacc tggggctatg cggacatcgc caaaaagcag
     5521 cccgtcacac agcaaacgtt gtttgagtta ggttcggtca gcaaaacatt tacgggcgtg
     5581 cttggtggcg acgctattgc tcgaggggaa atcaagttaa gcgatcccgc aacaaaatac
     5641 tggcctgaac ttaccgctaa acagtggaac gggatcacac tattacatct cgcaacctac
     5701 accgctggcg gcctgccatt gcaggtgccg gatgaggtga aatcctcaag cgacttgctg
     5761 cgcttctatc aaaactggca gcctgcatgg gctccaggaa cacaacgtct gtatgccaac
     5821 tccagtatcg gtttgttcgg cgcactggct gtgaagccgt ctggtttgag ttttgagcag
     5881 gcgatgcaaa cacgtgtctt ccagccactc aaactcaacc atacgtggat taatgtaccg
     5941 cccgcagaag aaaagaatta cgcctgggga tatcgcgaag gcaaggcagt tcatgtttcg
     6001 ccaggggcgt tagatgctga aacttatggt gtgaagtcga ccattgaaga tatggcctgc
     6061 tgggtacgaa gcaatatgaa tccccgtgat atcaacgaca aaacacttca gcaagggata
     6121 caactggcac aatctcgcta ctggcaaacc ggcgatatgt atcagggcct gggctgggaa
     6181 atgctggact ggccggtaaa tcctgacagc atcattaacg gcagtggcaa taaaattgca
     6241 ctggcagcac gccccgtaaa agcgattacg cccccaactc ctgcagtacg cgcatcatgg
     6301 gtacataaaa caggggcaac cggcggattt ggtagctatg tcgcgtttat tccagaaaaa
     6361 gagctgggta tagtgatgct ggctaacaaa aactatccca atccagcgag agtcaccgcc
     6421 gcctggcaga ttctcaacgc tctacagtaa aatttcatcg ggtccgaatt ttcggacctt
     6481 ttctgcgctt ttccttgctg tcatctacac ttagaaaaaa accagtaagg aaacatttat
     6541 gcgcctgctc cctctcgttg ccgcagcgac agctgcattt ctggtcgttg cctgcagttc
     6601 tcctacgccg ccgcgtggcg tgacagtagt gaataatttc gacgctaaac gctatctcgg
     6661 tacctggtat gagattgccc gttttgatca ccgttttgaa cgtggactgg aaaaagtcac
     6721 cgcaacatac agtctgcgtg atgacggcgg cctgaatgtc atcaataaag gctataaccc
     6781 tgacagagaa atgtggcagc agagtgaagg gaaagcgtac tttaccggcg caccaacacg
     6841 cgctgcgctg aaagtgtcat tctttggtcc tttctatggc ggttataacg tcattgcact
     6901 tgatcgggaa taccgccatg cgctggtttg cggcccggac cgcgactacc tgtggatact
     6961 ctcccgcacg ccaaccattt ctgacgaagt gaaacaggag atgctggcag tcgcgacccg
     7021 ggaagggttt gatgtcagta agtttatttg ggtacagcag cccggtagtt agtgagtgct
     7081 gagtttcaga ccaataatcc ccaatacgat taacgccaga ctcgccaggc gcatcgggtt
     7141 agcggactca ccgagcagta caatgccggt gatagccgcg ccgactgcgc caatacccgt
     7201 ccacacggca taagccgtcc ctactggtaa cgatttcatc gcccaggcaa gtagcgccat
     7261 actgacaatc atcgccgtca cggtaataac actcggcgtc aaacgactaa agccgtgggt
     7321 atatttcagg ccaacggccc ataccacttc cagcagacca gcaataacta agataatcca
     7381 ggacatatca ggctccggag aattggggcc gtccccggtg aaaagacgcg tttgcaggtc
     7441 gtcctgcaaa gctgatggtt gaacggatat tttgccaggt ggcaggggaa tttcaactat
     7501 taccttagtg actatcgcag aaaaaacaaa cggcacgaca cagctgtcgt accgttattg
     7561 cttattgcta ttgctgcgct ttcgttgctg cgccagaaat cgcgttaccg ccatcagaaa
     7621 tgtcttcacc aacgccacgc gtggtgttgc aggcagttaa tactgttgaa agcaccagaa
     7681 cagaaaagat cgctgcaatt gtcttcttca ccataacgtc ttccttttag gtaatgttat
     7741 ttatgtttgc ctatagcaaa ttaataatag acaacatcgc caaaaatgac ggaaatctga
     7801 tgatttttcg gaagagaaga aaaattagct ggcagcgcga gagatggagt tgccgagatg
     7861 tttgatgtct tcgccgaaac cgcgagcggt gttacagccc gtgagcagcg tgctggcaag
     7921 caaaacaaga acgataaggc gtttcatcat ctctgacctg aataagtgat ggtgcagcct
     7981 gcaggccgca ccacaaccgc attacttcac gcgagagacg tattcaccag agcgggtatc
     8041 cactttgatg acttcgccga tttgtacgaa cagcggaacc ttaaccacag cgccagtaga
     8101 cagggtagcc ggtttgccgc cagtacctgc ggtatcacct ttcaggcccg gatcggtatc
     8161 aacgatttcc agttcaacga agttcggcgg agtaacggag atcggctgac cattccacag
     8221 agttacgata cactctgcct gatccagcag ccatttagcg ttatcgccaa ttgcttttgc
     8281 atcagcagac agctgctcga aagtttcgtt gttcatgaag tgccagaact caccgtcgtt
     8341 gtacaggtaa gtcaggttca tatcgacaac atcagcgcct tcagcggaat cagtagattt
     8401 gaaggttttt tctacgcgag taccggtcag cagacgacgc agtttaacgc gagcaaatgc
     8461 ctggccttta cccggtttta cgaattcact cgcttcaacc gcgtaaggtt cgccgtctaa
     8521 catgatttta agaccagcac gaaaatcgtt gctatagtac gttgccataa ggccctctga
     8581 aatttgttaa ttggtagcta agccacaaaa tggcgcatat tgtaacccta aataccccat
     8641 ccagagaaga ttggttaacg caacttgccg atgttgtgac cgatcctgat gaacttctgc
     8701 gtcttttgaa tatagacgcg gacgaaaaac tgttggccgg acgcagcgcc aaaaagctgt
     8761 ttgccctgcg tgtgccccgc tcatttatcg atcgcatgga gaaaggcaat ccggacgatc
     8821 ctcttttgcg tcaggtactt acctcgcaag atgagtttgt cgtcgcgtcc ggattctcca
     8881 ccgacccact ggaagaacag cacagcgtag tgcctggttt gttgcataaa taccacaacc
     8941 gggcgctttt gctggtcaaa ggcggctgcg cggtaaattg ccgctattgc ttccgtcgcc
     9001 acttccccta tgccgaaaat cagggcaaca agcgtaactg gcagactgca cttgagtatg
     9061 ttgctgcgca tccggaactg gacgagatga ttttctctgg cggcgatccg ctgatggcga
     9121 aagatcacga gctggactgg ttgctcacac aactggaagc catcccgcat atcaaacgtc
     9181 tgcggattca cagccgtctg ccgattgtga tcccggcacg catcacagat gcgctggttg
     9241 aacgcttttc acattctacg ctgcaaatct tgctggtgaa tcacatcaac catgccaatg
     9301 agatagatga aacattccgt caggcgatgg ctaagttgcg ccgggtaggc gttactttgc
     9361 tgaaccagag cgttctgtta cgtgatgtga acgataacgc acaaacgctg gcaaacctga
     9421 gtaatgcgtt gttcgatgcc ggcgtgatgc cgtattacct gcatgtgctc gataaagtac
     9481 agggcgcggc gcattttatg gtgagtgatg acgaagcacg gcagattatg cgtgagttgc
     9541 tgacattggt gtcgggatat ctggtgccga aactggcgcg agaaattggc ggcgaaccca
     9601 gcaaaacgcc gctggatctc cagctacgcc agcagtaact gattaaacag ggaagttaaa
     9661 cattaaaatt gcctgatgcg ctacgcttat caggcctaca tcatgcattg aaattgaatg
     9721 gatttgcaat gaactgtagg ccggataagg cgtttacgcc gcatccggca agagcaacaa
     9781 acgcaagtac agcaacctgt cattaaactg agaaatttaa tctttgcacg ttgcataacc
     9841 tttaattatt catatgcatt gctgttgtta ctttttatat agctaacacc aataattaac
     9901 ctttcttttc tgtttatata gagtgagcac ggctatttat gttattttaa caactattac
     9961 taccaagccc
//
LOCUS       DAPHKZ010000360         4713 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.guided.219, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000360 DAPHKZ010000000
VERSION     DAPHKZ010000360.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4713
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.guided.219"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..985)
                     /gene="pepD"
                     /locus_tag="RH288_004796"
     CDS             complement(<1..985)
                     /gene="pepD"
                     /locus_tag="RH288_004796"
                     /EC_number="3.4.13.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-Ala-His dipeptidase"
                     /protein_id="HDV4033735.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDAL
                     KSLVNTYQDILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATP"
     gene            1246..1704
                     /gene="gpt"
                     /locus_tag="RH288_004797"
     CDS             1246..1704
                     /gene="gpt"
                     /locus_tag="RH288_004797"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDV4033736.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            1796..3040
                     /gene="frsA"
                     /locus_tag="RH288_004798"
     CDS             1796..3040
                     /gene="frsA"
                     /locus_tag="RH288_004798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HDV4033737.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            3098..3499
                     /gene="crl"
                     /locus_tag="RH288_004799"
     CDS             3098..3499
                     /gene="crl"
                     /locus_tag="RH288_004799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HDV4033738.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(3538..4593)
                     /gene="phoE"
                     /locus_tag="RH288_004800"
     CDS             complement(3538..4593)
                     /gene="phoE"
                     /locus_tag="RH288_004800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HDV4033739.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
BASE COUNT         1156 a         1152 c         1166 g         1239 t
ORIGIN      
        1 tcggggtggc gttcagcaga cgaataaagg tatcgcgaga tttcgcaatc agagcagctt
       61 tatcgttcgc tacagagtcc agcaacaagg ccagattctt ctctttctct gccagctcgt
      121 ttttcaggat gtcctgatag gtattcacca gagatttcag ggcgtcgact ttatcagctg
      181 cgacagcaat ggtcgcaaag gcttcacgcg ggatggcgtt acgcagtgtg ccaccgttga
      241 aatcgataag gcgcaggtcc agctcttccg catgacccgc caggaagcgc accagcagtt
      301 tgttggcatt acccaggcca acgtggattt caccgccgga gtgaccgcct tttagacctt
      361 ttaaggttaa cttgaaggtt tcaaagccag ctggaaccgc ttcacgatcc aaatgcaggt
      421 tggaggtgaa gtcgataccc cccgcgcaac ccatgtagat ttcaccttct tcttcggagt
      481 cggtgttaat cagaatatca gcctgcaacc agttgctctg taagccgaac gcaccgtcca
      541 taccggcttc ttcggtcatg gtcagcagca cttccagcgg gccgtgaacc acgttttcgt
      601 cagccagaac cgccagcgca gacgccatac caatgccgtt atctgcaccc agcgtggtgc
      661 cgcgcgcttt aacccattcg ccatcaatat aaggctggat aggatctttc gtgaagtcat
      721 gcacggtgtc gttatttttc tgcggcacca tatcgaggtg ggcctgcaag acgaccggtt
      781 tacgattttc catacctgcg gtggcaggtt tacgaatcag gatattacct acctgatcgc
      841 gttcgacatg gaaacctttc tcttttgccc aaccaacaat gtattcagcg agttgctctt
      901 catgatagga cgggtgagga atagaacaga ttttggcaaa aatatcccac agcggctgtg
      961 gagataattg agacagttca gacacgttaa gtctccttgt cgatcacccg caaaacagta
     1021 ttgcaggtca cagggttagc agaaaatgtt gtcaacacaa gacaggcttg cgagatatgt
     1081 ttgagaatac cactttatcc cgcgtcaggg agaggcagtg cgtaaaaaga cgcggactca
     1141 tgtgaaatac tggtttttag tgcgccagat ctctataatc tcgcgcaacc tattttcccc
     1201 tcgaacactt tttaagccgt agataaacag gctgggacac ttcacatgag cgaaaaatac
     1261 atcgtcacct gggacatgtt gcagatccat gcacgtaaac tcgcaagccg actgatgcct
     1321 tctgaacaat ggaaaggcat tattgccgta agccgtggcg gtctggtacc gggtgcgtta
     1381 ctggcgcgtg aactgggtat tcgtcatgtc gataccgttt gtatttccag ctacgatcac
     1441 gacaaccagc gcgagcttaa agtgctgaaa cgcgcagaag gcgatggcga aggcttcatc
     1501 gttattgatg acctggtgga taccggtggt actgcggttg cgattcgtga aatgtatcca
     1561 aaagcgcact ttgtcaccat cttcgcaaaa ccggctggtc gtccgctggt tgatgactat
     1621 gttgttgata tcccgcaaga tacctggatt gaacagccgt gggatatggg cgtcgtattc
     1681 gtcccgccaa tctccggtcg ctaatctttt caacgcctgg cactgccggg cgttgttctt
     1741 tttaacttca ggcgggttac aatagtttcc agtaagtatt ctggaggctg catccatgac
     1801 acaggcaaac ctgagcgaaa ccctgttcaa accccgcttt aaacatcctg aaacctcgac
     1861 gctagtccgc cgctttaatc acggcgcaca accgcctgtg cagtcggctc ttgatggtaa
     1921 aaccatccct cactggtatc gcatgattaa ccgtctgatg tggatctggc gcggtattga
     1981 cccacgtgaa atcctcgacg tccaggcacg tattgtgatg agcgatgctg aacgtaccga
     2041 cgatgattta tacgatactg tgattggcta ccgtggtggc aactggattt atgagtgggc
     2101 cacccaggcg atggtgtggc aacaaaaagc ctgtgcggaa gaagatccgc aactcagtgg
     2161 tcgtcactgg ctgcatgcgg ctacgttgta taacattgct gcctatcctc atctgaaagg
     2221 agatgacctg gccgagcaag cgcaggcttt gtcaaaccgc gcctatgaag aggccgctca
     2281 gcgtctgccg ggcacgatgc ggcagatgga gtttaccgta cccggcggtg cgcccatcac
     2341 cggctttttg catatgccga aaggcgatgg cccgttcccg acagtattaa tgtgtggtgg
     2401 tctggatgcg atgcagacgg actattacag cctgtacgaa cgttattttg cgccgcgcgg
     2461 cattgcgatg ctgactattg atatgccgtc ggtgggcttt tcttcaaaat ggaagctgac
     2521 ccaggactcc agcctgttgc atcagcacgt cttaaaggcg ctgcctaacg taccgtgggt
     2581 ggatcacact cgcgtcgcgg cctttggttt ccgtttcggc gctaacgttg ccgtgcgtct
     2641 ggcatacctt gaatcgccgc gtctgaaagc ggttgcctgt cttggtccgg tagttcatac
     2701 cctgttgagt gattttaagt gccagcaaca ggtgccggaa atgtatcttg acgttctggc
     2761 gagtcgtttg gggatgcatg atgcttccga cgaagcgttg cgcgtggagc tgaatcgcta
     2821 ttcattaaaa gtgcaaggat tgctgggacg tcgctgccca acgccaatgt tatcgggcta
     2881 ctggaagaac gatccgttca gcccggaaga ggactcacgc ttaatcacct catcatctgc
     2941 tgacggtaaa ttattagaga tcccatttaa cccggtgtat cggaattttg acaaaggtct
     3001 tcaggaaatc acagactgga tcgaaaaacg tttgtgttaa aaatttgcta aaatttgcca
     3061 atttggtaaa acagttgcat cacaacagga gattgcaatg acgttaccga gtggacaccc
     3121 gaagagcaga ttgatcaaaa aatttaccgc actaggcccg tatattcgtg aaggtaagtg
     3181 cgaagataat cgattctttt tcgattgtct ggctgtatgc gtcaacgtga aaccggcacc
     3241 ggaagtgcgt gagttctggg gctggtggat ggagcttgaa gcgcaggaat cccgttttac
     3301 ctacagttac cagtttggtc tgttcgataa agcaggcgac tggaagagtg ttccggtaaa
     3361 agacactgaa gtggttgaac gactggagca caccctacgt gagtttcacg agaagctgcg
     3421 tgaactgctg acgacgctga atctgaagct ggaaccggcg gatgattttc gtgatgaacc
     3481 ggtgaagtta acggcgtgag tgaaatgtgc cggatgtatc acatccggca atatccatta
     3541 aaactgatag gtcatgccaa ccgcgacaat atcatcatta ttaatattca atttgttatc
     3601 gctatccagt tggttgattt tataatcaac aaacgctgac atatttttgt tgaaataata
     3661 cgtagcaccg acgtcgatat aattgaccag atcttcatca ccgatacctt caatatcttt
     3721 ccctttcgat aagacataac ccagcgatgg acgcagacca aagtcaaact ggtattgagc
     3781 gaccgcttca aagttctgtg tcttattggc aaagccgcca gttattggcg tcattttgcg
     3841 tgtttcagaa tagaaagttg ccagataaat attattggca tcgtatttca gacctgttgc
     3901 ccatgcttct gcacgcttgc ctgtgccacg gctttgcagg ttctgctcgt tggtgcgatc
     3961 tgagttggta taggccccac taatggcgaa atcgctgccg ccaaagtcat atgtcaatga
     4021 cgtgccgaag ccatcgccgt tttgcttttt aacgtcgcgg ttttcgtttt tcccttgata
     4081 ttgcagggtt aagttcaggc catcgataac gccgaagaag tcggtgttcc gatacgtcgc
     4141 cagaccgctg gcgcgtttgg tcataaagtt gtcggtctgc gccgaggaat cgccaccaaa
     4201 ttccgggaac atatcggtcc aggcttccac gtcatacaac gcccccaggt tacgaccata
     4261 atcgaaagaa cccaaatctt tatatttcaa cccggcaaaa gcgagacgcg ttttttgctg
     4321 tgcagtatca ctctctgctt tattaccggc aaactctgct tcccaacgac cataaccagt
     4381 cagttgatcg ttaatttgtg tttcgccttt aaaaccaaaa cggatataac tctggtcgcc
     4441 atctttactg gcgttatcac tcatataatg catggcttta actttgccat agacatccag
     4501 tttattaccg tctttattat atatttctgc agcctgtaca gatgcagatg ccacaatgcc
     4561 catcaccact aatgccagag tgctcttttt cattttcatt cctgatttta attaacgcgc
     4621 gaatattcag cgggagagtc ccgttgaaaa caggaaagtt tttaacctga gattgttaaa
     4681 gatatattac agattaataa tattcttaaa atg
//
LOCUS       DAPHKZ010000361         4468 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.guided.223, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000361 DAPHKZ010000000
VERSION     DAPHKZ010000361.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4468
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.guided.223"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..294)
                     /locus_tag="RH288_004801"
     CDS             complement(<1..294)
                     /locus_tag="RH288_004801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HDV4033740.1"
                     /translation="MCELDILHDSLYQFCPELHLKRLNSLTLACHALLDCKTLTLTEL
                     GRNLPTKARTKHNIKRIDRLLGNRHLHKERLAVYRWHASFICSGNTMPIVLVDW"
     gene            580..1383
                     /locus_tag="RH288_004802"
                     /note="aph(3'')-Ib"
     CDS             580..1383
                     /locus_tag="RH288_004802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="HDV4033741.1"
                     /translation="MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASR
                     RGELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAW
                     PSMGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLL
                     ARVERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLA
                     LMIANAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
     gene            1383..2219
                     /locus_tag="RH288_004803"
     CDS             1383..2219
                     /locus_tag="RH288_004803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="HDV4033742.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLK
                     PIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATE
                     IAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMM
                     SNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDP
                     RRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQT
                     SY"
     gene            complement(2289..>4468)
                     /locus_tag="RH288_004804"
     CDS             complement(2289..>4468)
                     /locus_tag="RH288_004804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001475310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV4033743.1"
                     /translation="NTVRQVSLSNGQNDYQGATYVQMGTLRTDADGALGNTRELNISN
                     AAIVDLNGSTQTVETFTGQMGSTVLFKEGALTVNKGGISQGELTGGGNLNVTGGTLAI
                     EGLNARYNALTSISPNAEVSLDNTQGLGRGNIANDGLLTLKNVTGELRNSISGKGIVS
                     ATARTDVELDGDNSRFVGQFNIDTGSALSVNEQKNLGDASVINNGLLTISTERSWAMT
                     HSISGSGDVTKLGTGILTLNNDSAAYQGTTDIVGGEIAFGSDSAINMASQHINIHNSG
                     VMSGNVTTAGDMNVMPGGALRVAKTTIGGNLENGGTVQMNSEGGKPGNVLTVNGNYTG
                     NNGLMTFNATLGGDNSPTDKMNVKGDTQGNTRVRVDNIGGVGAQTVNGIELIEVGGNS
                     AGNFALTTGTVEAGAYVYTLAKGKGNDEKNWYLTSKWDGVTPADTPDPINNPPVVDPE
                     GPSVYRPEAGSYISNIAAANSLFSHRLHDRLGEPQYTDSLHSQGSASSMWMRHVGGHE
                     RSRAGDGQLNTQANRYVLQLGGDLAQWSSNAQDRWHLGVMAGYANQHSNTQSNRVGYK
                     SDGRISGYSAGLYATWYQNDANKTGAYVDSWALYNWFDNSVSSDNRSADDYDSRGVTA
                     SVEGGYTFEAGTFSGSEGTLNTWYVQPQAQITWMGVKDSDHTRKDGTRIETEGDGNVQ
                     TRLGVKTYLNSHHQRDDGKQREFQPYIEANWMGSFAGEGEILR"
BASE COUNT          957 a         1225 c         1147 g         1139 t
ORIGIN      
        1 ccagtcaaca agtacaatgg gcatcgtatt gcccgaacag ataaagctag catgccaacg
       61 gtatacagcg agtcgctctt tgtggaggtg acgattacct aacaatcggt cgattcgttt
      121 gatgttatgt tttgttctcg ctttggttgg caggttacgg ccaagttcgg taagagtgag
      181 agttttacag tcaagtaagg cgtggcaagc caacgttaag ctgttgagtc gttttaagtg
      241 taattcgggg cagaattggt aaagagagtc gtgtaaaata tcgagttcgc acattttgtt
      301 gtctgattat tgatttttgg cgaaaccatt tgatcatatg acaagatgtg tatctacctt
      361 aacttaatga ttttgataaa aatcattagg ggattcatca gcactcggct ggaaatcgcc
      421 ggtggcattt gagaaaaaag ccgcttaaaa tgagagatag accggaacac aaccggtgca
      481 agaccatgga aagcatgttc tcggacttac gtagcaactc gtttcttttc gcaggttgag
      541 ccacctccgc gcttcatcag aaaactgaag gaacctccat tgaatcgaac taatattttt
      601 tttggtgaat cgcattctga ctggttgcct gtcagaggcg gagaatctgg tgattttgtt
      661 tttcgacgtg gtgacgggca tgccttcgcg aaaatcgcac ctgcttcccg ccgcggtgag
      721 ctcgctggag agcgtgaccg cctcatttgg ctcaaaggtc gaggtgtggc ttgccccgag
      781 gtgatcaact ggcaggagga acaggagggt gcatgcttgg tgataacggc aattccggga
      841 gtaccggcgg ctgatctgtc tggagcggat ttgctcaaag cgtggccgtc aatggggcag
      901 caacttggcg ctgttcacag cctatcggtt gatcaatgtc cgtttgagcg caggctgtcg
      961 cgaatgttcg gacgcgccgt tgatgtggtg tcccgcaatg ccgtcaatcc cgacttctta
     1021 ccggacgagg acaagagtac gccgcagctc gatcttttgg ctcgtgtcga acgagagcta
     1081 ccggtgcggc tcgaccaaga gcgcaccgat atggttgttt gccatggtga tccctgcatg
     1141 ccgaacttca tggtggaccc taaaactctt caatgcacgg gtctgatcga ccttgggcgg
     1201 ctcggaacag cagatcgcta tgccgatttg gcactcatga ttgctaacgc cgaagagaac
     1261 tgggcagcgc cagatgaagc agagcgcgcc ttcgctgtcc tattcaatgt attggggatc
     1321 gaagcccccg accgcgaacg ccttgccttc tatctgcgat tggaccctct gacttggggt
     1381 tgatgttcat gccgcctgtt tttcctgctc attggcacgt ttcgcaacct gttctcattg
     1441 cggacacctt ttccagcctc gtttggaaag tttcattgcc agacgggact cctgcaatcg
     1501 tcaagggatt gaaacctata gaagacattg ctgatgaact gcgcggggcc gactatctgg
     1561 tatggcgcaa tgggagggga gcagtccggt tgctcggtcg tgagaacaat ctgatgttgc
     1621 tcgaatatgc cggggagcga atgctctctc acatcgttgc cgagcacggc gactaccagg
     1681 cgaccgaaat tgcagcggaa ctaatggcga agctgtatgc cgcatctgag gaacccctgc
     1741 cttctgccct tctcccgatc cgggatcgct ttgcagcttt gtttcagcgg gcgcgcgatg
     1801 atcaaaacgc aggttgtcaa actgactacg tccacgcggc gattatagcc gatcaaatga
     1861 tgagcaatgc ctcggaactg cgtgggctac atggcgatct gcatcatgaa aacatcatgt
     1921 tctccagtcg cggctggctg gtgatagatc ccgtcggtct ggtcggtgaa gtgggctttg
     1981 gcgccgccaa tatgttctac gatccggctg acagagacga cctttgtctc gatcctagac
     2041 gcattgcaca gatggcggac gcattctctc gtgcgctgga cgtcgatccg cgtcgcctgc
     2101 tcgaccaggc gtacgcttat gggtgccttt ccgcagcttg gaacgcggat ggagaagagg
     2161 agcaacgcga tctagctatc gcggccgcga tcaagcaggt gcgacagacg tcatactaga
     2221 tatcaagcga cttctcctat cccctgggaa cacatcaatc ttaccggaga atatcgttgg
     2281 ccaaagcctt agcgtaggat ttcgccctct cccgcaaacg accccatcca gttcgcttca
     2341 atgtaaggct ggaactcacg ctgtttacca tcgtcacgct ggtgatggct gttcaggtag
     2401 gttttcaccc caagtcgcgt ttgcacattt ccgtcgcctt ccgtttcaat gcgcgttccg
     2461 tctttccggg tatggtcgga atctttcaca cccatccagg tgatttgcgc ctgtggctgg
     2521 acgtaccagg tattcagcgt cccttcgctg ccgctaaatg ttcccgcttc aaaggtatac
     2581 ccaccctcaa cagaggccgt cacaccgcga gaatcatagt cgtcagcaga acggttatcg
     2641 gaactgacgc tgttatcaaa ccagttatac agcgcccagc tgtcaacata agcgccggtc
     2701 ttattcgcat cgttctgata ccaggtcgcg tacagcccag cgctgtaacc gctgatgcgc
     2761 ccatccgatt tataacccac acgattactc tgagtattac tgtgctgatt ggcgtagcct
     2821 gccatcacgc caagatgcca gcgatcctgc gcgttgctac tccactgcgc caaatcgccg
     2881 cctagctgca atacatagcg gttagcctga gtatttagct gaccgtcacc ggcccttgaa
     2941 cgttcgtgcc ctccgacatg acgcatccac atactgcttg ccgacccctg agagtgcagt
     3001 gaatctgtat actgcggctc acccagacgg tcgtgtaaac gatggctaaa cagcgagttg
     3061 gctgcggcaa tgttgctgat atagcttccg gcctccgggc gataaactga tgggccttcc
     3121 ggatccacaa cagggggatt attgatggga tcgggtgtat ccgctggcgt tacgccgtcc
     3181 catttactgg tcagatacca gtttttctcg tcattcccct tccctttagc cagcgtgtag
     3241 acgtaagccc cagcttcgac agttccggtg gtcagcgcga agttacctgc agaattaccg
     3301 ccaacctcaa tgagttcaat accgttgacc gtttgtgcac cgacgccgcc aatgttatca
     3361 acccgaacgc gagtgttccc ttgggtatcg cctttcacgt tcatcttatc ggtgggcgaa
     3421 ttatcgccgc ccagcgtcgc gttgaacgtc atcaggccat tgtttccggt atagttgccg
     3481 ttaacggtca gtacattccc cggtttcccc ccttcgctat tcatttgaac cgtgccgcca
     3541 ttctccaggt tgccgccgat agtggtttta gcgacacgca gtgccccccc aggcataacg
     3601 ttcatatcac ctgcagtggt gacatttccc gacatcacac cgctgttatg gatattaatg
     3661 tgttgacttg ccatattaat ggcagagtcg gaaccgaaag caatttcccc ccccacgata
     3721 tccgtcgtac cctgatacgc cgcggaatcg ttgttaagag tcaggatccc ggtacccagt
     3781 tttgtcacat caccgctacc gctgatactg tgcgtcatcg cccagctacg ctcagtggag
     3841 atggtgagca ggccattatt gataacggaa gcatcaccca ggtttttctg ctcgttgacg
     3901 ctgagcgcgc tgcctgtatc aatgttgaat tgccccacaa agcggctatt atcgccatcc
     3961 aactctacat ctgtcctggc ggttgcgctc acgataccct tcccgcttat gctattacgc
     4021 agttcgccag tcacgttttt tagcgttaac agaccgtcat tggcaatatt tcctctgcct
     4081 aacccctgag tattatcgag gctgacttcc gcatttgggc taatgctggt taacgcattg
     4141 tagcgtgcat taagcccctc gatagccagc gttccccctg taacattcag gtttccgcca
     4201 cctgtcagtt caccctgact gatcccacct ttatttaccg tcagcgcccc ctctttgaac
     4261 aaaacagtcg aacccatctg cccggtgaat gtctctaccg tctgcgtcga tccattaaga
     4321 tcgacgatgg ccgcgttgct gatgttcagt tcccgggtgt tgccaagtgc accatccgca
     4381 tcggtacgta atgtccccat ctgaacgtag gttgccccct gatagtcgtt ctgaccgttg
     4441 gaaagcgaaa cctgtcgcac cgtattga
//
LOCUS       DAPHKZ010000362         3820 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.guided.231, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000362 DAPHKZ010000000
VERSION     DAPHKZ010000362.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3820
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.guided.231"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..894
                     /locus_tag="RH288_004805"
     CDS             <1..894
                     /locus_tag="RH288_004805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEc9 family transposase"
                     /protein_id="HDV4033744.1"
                     /translation="LTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYNIQFAFCD
                     ELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSDDLEILFRMDSGYFDEKIIETIES
                     LGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRETTELYTKLVKWEKDRRFVVSRVLK
                     PEKERAQLSLLEGSEYDYFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGHL
                     LLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTAR
                     YVIMKLSENYPYKGVYEKCLV"
     gene            1218..2363
                     /locus_tag="RH288_004806"
     CDS             1218..2363
                     /locus_tag="RH288_004806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C beta-lactamase CMY-2"
                     /protein_id="HDV4033745.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQA
                     IPGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGE
                     IKLSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQP
                     QWTPGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKD
                     YAWGYREGKPVHVSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQ
                     SRYWRIGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVH
                     KTGSTGGFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
     gene            2457..2990
                     /locus_tag="RH288_004807"
     CDS             2457..2990
                     /locus_tag="RH288_004807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HDV4033746.1"
                     /translation="MRILPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLDKVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGDPSRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEMKQQMLAIAT
                     REGFEVNKLIWVKQPGA"
     gene            complement(2987..3304)
                     /gene="sugE"
                     /locus_tag="RH288_004808"
     CDS             complement(2987..3304)
                     /gene="sugE"
                     /locus_tag="RH288_004808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDV4033747.1"
                     /translation="MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIA
                     MLSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKL
                     STH"
     gene            3356..3820
                     /locus_tag="RH288_004809"
                     /pseudo
     CDS             3356..3820
                     /locus_tag="RH288_004809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632353.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1113 a          856 c          915 g          936 t
ORIGIN      
        1 ttgacatcca ttacgattga tattgatagt agtgtaatta acgtagaagg tcatcaagaa
       61 ggtgcgtcaa aaggatataa tcctaagaaa ctgggaaacc gatgctacaa tatccaattt
      121 gcattttgcg acgaattaaa agcatatgtt accggatttg taagaagtgg caatacttac
      181 actgcaaacg gtgctgcgga aatgatcaaa gaaattgttg ctaacatcaa atcagacgat
      241 ttagaaattt tatttcgaat ggatagtggc tactttgatg aaaaaattat cgaaacgata
      301 gaatctcttg gatgcaaata tttaattaaa gccaaaagtt attctacact cacctcacaa
      361 gcaacgaatt catcaattgt attcgttaaa ggagaagaag gtagagaaac tacagaactg
      421 tatacaaaat tagttaaatg ggaaaaagac agaagatttg tcgtatctcg cgtactgaaa
      481 ccagaaaaag aaagagcaca attatcactt ttagaaggtt ccgaatacga ctactttttc
      541 tttgtaacaa atactacctt gctttctgaa aaagtagtta tatactatga aaagcgtggt
      601 aatgctgaaa actatatcaa agaagccaaa tacgacatgg cggtgggtca tctcttgcta
      661 aagtcatttt gggcgaatga agccgtgttt caaatgatga tgctttcata taacctattt
      721 ttgttgttca agtttgattc cttggactct tcagaataca gacagcaaat aaagaccttt
      781 cgtttgaagt atgtatttct tgcagcaaaa ataatcaaaa ccgcaagata tgtaatcatg
      841 aagttgtcgg aaaactatcc gtacaaggga gtgtatgaaa aatgtctggt ataataagaa
      901 tatcatcaat aaaattgagt gttgctctgt ggataacttg cagagtttat taagtatcat
      961 tgcagcaaag atgaaatcaa tgatttatca aaaatgattg aaaggtggtt gtaaataatg
     1021 ttacaatgtg tgagaagcag tctaaattct tcgtgaaata gtgatttttg aagctaataa
     1081 aaaacacacg tggaatttag gaaaaactta tatctgctgc taaatttaac cgtttgtcaa
     1141 cacggtgcaa atcaaacaca ctgattgcgt ctgacgggcc cggacacctt tttgctttta
     1201 attacggaac tgatttcatg atgaaaaaat cgttatgctg cgctctgctg ctgacagcct
     1261 ctttctccac atttgctgcc gcaaaaacag aacaacagat tgccgatatc gttaatcgca
     1321 ccatcacccc gttgatgcag gagcaggcta ttccgggtat ggccgttgcc gttatctacc
     1381 agggaaaacc ctattatttc acctggggta aagccgatat cgccaataac cacccagtca
     1441 cgcagcaaac gctgtttgag ctaggatcgg ttagtaagac gtttaacggc gtgttgggcg
     1501 gcgatgctat cgcccgcggc gaaattaagc tcagcgatcc ggtcacgaaa tactggccag
     1561 aactgacagg caaacagtgg cagggtatcc gcctgctgca cttagccacc tatacggcag
     1621 gcggcctacc gctgcagatc cccgatgacg ttagggataa agccgcatta ctgcattttt
     1681 atcaaaactg gcagccgcaa tggactccgg gcgctaagcg actttacgct aactccagca
     1741 ttggtctgtt tggcgcgctg gcggtgaaac cctcaggaat gagttacgaa gaggcaatga
     1801 ccagacgcgt cctgcaacca ttaaaactgg cgcatacctg gattacggtt ccgcagaacg
     1861 aacaaaaaga ttatgcctgg ggctatcgcg aagggaagcc cgtacacgtt tctccgggac
     1921 aacttgacgc cgaagcctat ggcgtgaaat ccagcgttat tgatatggcc cgctgggttc
     1981 aggccaacat ggatgccagc cacgttcagg agaaaacgct ccagcagggc attgcgcttg
     2041 cgcagtctcg ctactggcgt attggcgata tgtaccaggg attaggctgg gagatgctga
     2101 actggccgct gaaagctgat tcgatcatca acggcagcga cagcaaagtg gcattggcag
     2161 cgcttcccgc cgttgaggta aacccgcccg cccccgcagt gaaagcctca tgggtgcata
     2221 aaacgggctc cactggtgga tttggcagct acgtagcctt cgttccagaa aaaaaccttg
     2281 gcatcgtgat gctggcaaac aaaagctatc ctaaccctgt ccgtgtcgag gcggcctggc
     2341 gcattcttga aaagctgcaa taactgacga tgaggcccag gatattgggc ctcctttctt
     2401 tctctttttt tcctgttgtc atctacactt aacaaaaata cagcaaggaa aatcccatgc
     2461 gcattttgcc cgtcgttgct gcagttacgg ctgcattcct ggttgtcgcg tgtagctccc
     2521 cgacaccgcc gaaaggcgtt accgtggtaa ataactttga tgccaaacgc tatctgggaa
     2581 cctggtatga aattgcgcgc ttcgaccatc gtttcgagcg cggattggat aaagtgaccg
     2641 caacatacag cttgcgcgac gacggcggca tcaacgttat taacaagggc tataaccctg
     2701 acagggagat gtggcagaaa acggaaggga aagcctattt caccggcgac ccaagcagag
     2761 ccgcgcttaa ggtttctttt ttcggcccct tctatggcgg gtataacgta attgcactcg
     2821 accgggaata tcgtcacgcg ctggtttgtg gtccggatcg cgactacctg tggatccttt
     2881 cacggacccc tactatttca gatgaaatga aacagcaaat gttagccatc gcgacccggg
     2941 aagggtttga agtgaataaa ctgatttggg tgaaacagcc tggcgcttag tgagtgctca
     3001 gcttcagacc aataatgcca gcaacgatca gcccaaggct cagcaaacgt gccgggctgg
     3061 cagactcacc cagcagcaaa atccctgtaa tggccgcccc aacagcgcca ataccggtcc
     3121 agaccgcata agcggttcct acaggcaacg tgcgcattgc ccaagagagc atggcgatac
     3181 tgacgatcat cgccgcaata gtgataatgc ttggcgtaag acgcgtaaaa ccgtgggtgt
     3241 atttcaggcc aatcgcccag acaacttcga gcaaacctgc aattaataaa acgatccagg
     3301 acatatcagg ctccagaaca atggggccgt ccccggtgaa agaagcgttt gcaggtgggt
     3361 tattcttgct ttttgccgga gtgccgatgg cagaatcatc tgcagtgaag ggtatgctca
     3421 tgctctttat caactgacat gtccggtgcc tgtggacagc aaactggaac gaaacacgct
     3481 cactgctctt ctgaatgtgg ccagctggct taaaagaaag ccaggtacgc cggaattaag
     3541 tctggaaagg cccctgtttg atacagaagt ttatgttaat ggtgaaaaga aatatgtact
     3601 gccggatttc attgtcacag caagggctcc tgacggaaag acggccagag tggtcatcga
     3661 aacgatggga tatgaagaca gtgattactg cgcgagaaaa tccaggcagc ataccggcat
     3721 gaagcagatt ggtgttctgc ataccgatcc accgaaatgg ctggataacg atcatccccc
     3781 ttttaagaaa catatgtacg gtgtttttat gcatctcagg
//
LOCUS       DAPHKZ010000363         3550 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16140
            SAMN37211428-rid19350533.guided.237, whole genome shotgun sequence.
ACCESSION   DAPHKZ010000363 DAPHKZ010000000
VERSION     DAPHKZ010000363.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211428
            Sequence Read Archive: SRR25824434
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875158.1
            Genome Coverage       :: 58x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 03:09:13
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,814
            CDSs (total)                      :: 4,745
            Genes (coding)                    :: 4,639
            CDSs (with protein)               :: 4,639
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 41 of 106
            Pseudo Genes (incomplete)         :: 51 of 106
            Pseudo Genes (internal stop)      :: 38 of 106
            Pseudo Genes (multiple problems)  :: 22 of 106
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3550
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211428-rid19350533.guided.237"
                     /isolate="ARS-CC16140"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            166..486
                     /locus_tag="RH288_004810"
     CDS             166..486
                     /locus_tag="RH288_004810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDV4033748.1"
                     /translation="MIAVIFEVQIQPDQQTRYLTLAEELRPLLSHVAGFISIERFQSL
                     ATEGKMLSLSWWENEYAVLQWKNHVLHAKAQQEGRESIFDFYKISIAHITREYSFKKD
                     KDNV"
     gene            479..865
                     /locus_tag="RH288_004811"
     CDS             479..865
                     /locus_tag="RH288_004811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HDV4033749.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKQEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            873..1559
                     /locus_tag="RH288_004812"
     CDS             873..1559
                     /locus_tag="RH288_004812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDV4033750.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(1537..2160)
                     /gene="tetR(B)"
                     /locus_tag="RH288_004813"
     CDS             complement(1537..2160)
                     /gene="tetR(B)"
                     /locus_tag="RH288_004813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HDV4033751.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQTIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            2242..3447
                     /gene="tet(B)"
                     /locus_tag="RH288_004814"
     CDS             2242..3447
                     /gene="tet(B)"
                     /locus_tag="RH288_004814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HDV4033752.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
BASE COUNT          991 a          646 c          787 g         1126 t
ORIGIN      
        1 caaaattata agagaaggag aacatgataa gcgcaggccg agcaatttaa agaagtgtga
       61 tatacaacat aaaacagcag catgaccttt ctatatttcg ttgcttatcg aagtgttaat
      121 tttcgggtgg attactctgt ttgttgatta ataacggaga aaaatatgat tgctgtaata
      181 tttgaggtgc aaatacaacc cgaccaacaa actcgctatt tgactttagc tgaggagtta
      241 agaccactat taagtcatgt agctggtttt atttcaattg aacgttttca aagtctagct
      301 acagaaggaa aaatgttatc gctatcttgg tgggaaaacg aatacgcagt tctgcaatgg
      361 aaaaatcatg ttttacatgc gaaagctcaa caagaagggc gagagtcaat atttgatttt
      421 tacaaaatta gtattgctca tattactcgc gaatattcat ttaaaaagga caaggataat
      481 gtttgatgtt cacgttgttt tagataatca aataggacaa ttagcattac taggaaaaac
      541 attaggtaat aaaggtattg gattggaagg gggagggata tttacggttg gtgatgaatg
      601 ccatgctcat tttcttgttg aacaaggaaa ggaagctaaa atagcgctag agcaagctgg
      661 actgttagta cttgcgatcc ggacaccatt aattcgtaag ttaaaacagg aaaaaccggg
      721 ggaacttggc gaaatagcac gagtattggc ggagaataac attaatattt tagtgcaata
      781 cagtgaccat gctaaccaac tgatattaat aacggacaat gatagtatgg ctgcatctgt
      841 tacgctccct tgggcaataa agtgaacttg cgatggctaa tttaatacga aaagaggtta
      901 cctttgagtc ctcaatagcc gcgatagggg cggctatgtc tgacatttca cgagttaaaa
      961 tactcagtgc tttgatggat gggcgagctt ggacggccac tgagctaagt tctgtggcga
     1021 atatatcagc ttcaacggcg agcagtcatt tatctaaatt attagattgc cagctaatca
     1081 cagtagtagc tcaaggcaag catcgttatt ttcggctagc aggaaaagat attgctgaat
     1141 tgatggaaag tatgatgggg atctccttaa accatggcgt acatgccaaa gtttccacgc
     1201 cagtgcattt acgaaaagca cgtacttgct atgatcattt agctggcgaa gttgccgtta
     1261 agatctatga ttccctttgt caacagcaat ggatcactga aaatggttca atgatcacat
     1321 taagtggtat tcaatatttt catgaaatgg gaattgacgt tccttccaaa cattcacgta
     1381 aaatctgttg tgcgtgttta gattggagtg aacgccgttt ccatttaggt gggtacgttg
     1441 gagccgcatt attttcgctt tatgaatcta aagggtggtt aactcgacat cttggttacc
     1501 gtgaagttac catcacggaa aaaggttatg ctgcttttaa gacccacttt cacatttaag
     1561 ttgtttttct aatccgcata tgatcaattc aaggccgaat aagaaggctg gctctgcacc
     1621 ttggtgatca aataattcga tagtttgtcg taataatggc ggcatactat cagtagtagg
     1681 tgtttccctt tcttctttag cgacttgatg ctcttgatct tccaatacgc aacctaaagt
     1741 aaaatgcccc acagcgctga gtgcatataa tgcattctct agtgaaaaac cttgttggca
     1801 taaaaaggct aattgatttt cgagagtttc atactgtttt tctgtaggcc gtgtacctaa
     1861 atgtactttt gctccatcgc gatgacttag taaagcacat ctaaaacttt tagcgttatt
     1921 acgtaaaaaa tcttgccagc tttccccttc taaagggcaa aagtgagtat ggtgcctatc
     1981 taacatctca atggctaagg cgtcgagcaa agcccgctta ttttttacat gccaatacaa
     2041 tgtaggctgc tctacaccta gcttctgggc gagtttacgg gttgttaaac cttcgattcc
     2101 gacctcatta agcagctcta atgcgctgtt aatcacttta cttttatcta atctagacat
     2161 cattaattcc taatttttgt tgacactcta tcattgatag agttatttta ccactcccta
     2221 tcagtgatag agaaaagtga aatgaatagt tcgacaaaga tcgcattggt aattacgtta
     2281 ctcgatgcca tggggattgg ccttatcatg ccagtcttgc caacgttatt acgtgaattt
     2341 attgcttcgg aagatatcgc taaccacttt ggcgtattgc ttgcacttta tgcgttaatg
     2401 caggttatct ttgctccttg gcttggaaaa atgtctgacc gatttggtcg gcgcccagtg
     2461 ctgttgttgt cattaatagg cgcatcgctg gattacttat tgctggcttt ttcaagtgcg
     2521 ctttggatgc tgtatttagg ccgtttgctt tcagggatca caggagctac tggggctgtc
     2581 gcggcatcgg tcattgccga taccacctca gcttctcaac gcgtgaagtg gttcggttgg
     2641 ttaggggcaa gttttgggct tggtttaata gcggggccta ttattggtgg ttttgcagga
     2701 gagatttcac cgcatagtcc cttttttatc gctgcgttgc taaatattgt cgctttcctt
     2761 gtggttatgt tttggttccg tgaaaccaaa aatacacgtg ataatacaga taccgaagta
     2821 ggggttgaga cgcaatcgaa ttcggtatac atcactttat ttaaaacgat gcccattttg
     2881 ttgattattt atttttcagc gcaattgata ggccaaattc ccgcaacggt gtgggtgcta
     2941 tttaccgaaa atcgttttgg atggaatagc atgatggttg gcttttcatt agcgggtctt
     3001 ggtcttttac actcagtatt ccaagccttt gtggcaggaa gaatagccac taaatggggc
     3061 gaaaaaacgg cagtactgct cggatttatt gcagatagta gtgcatttgc ctttttagcg
     3121 tttatatctg aaggttggtt agttttccct gttttaattt tattggctgg tggtgggatc
     3181 gctttacctg cattacaggg agtgatgtct atccaaacaa agagtcatca gcaaggtgct
     3241 ttacagggat tattggtgag ccttaccaat gcaaccggtg ttattggccc attactgttt
     3301 gctgttattt ataatcattc actaccaatt tgggatggct ggatttggat tattggttta
     3361 gcgttttact gtattattat cctgctatcg atgaccttca tgttaacccc tcaagctcag
     3421 gggagtaaac aggagacaag tgcttagtta tttcgtcacc aaatgatgtt attccgcgaa
     3481 atataatgac cctcttgata acccaagagg gcatttttta cgataaagaa gatttagctt
     3541 caaataaaac
//
